# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF2946 PF11162.3 CBZ22984.1 - 9.1e-14 51.7 0.3 1.8e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Rhabdo_glycop PF00974.13 CBZ22984.1 - 0.00016 20.0 0.8 0.00027 19.3 0.5 1.3 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Shisa PF13908.1 CBZ22984.1 - 0.0004 20.5 0.1 0.0022 18.2 0.0 2.0 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator RCR PF12273.3 CBZ22984.1 - 0.0054 17.2 0.6 0.0089 16.5 0.0 1.7 2 0 0 2 2 1 1 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.11 CBZ22984.1 - 0.01 14.1 0.9 0.011 14.1 0.0 1.4 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 CBZ22984.1 - 0.035 14.5 0.9 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Hum_adeno_E3A PF05393.6 CBZ22984.1 - 0.086 12.5 1.9 0.26 10.9 1.3 1.8 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein TMEM154 PF15102.1 CBZ22984.1 - 0.14 11.9 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family LRR19-TM PF15176.1 CBZ22984.1 - 0.14 11.8 0.1 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Tweety PF04906.8 CBZ22984.1 - 0.37 9.1 3.6 0.2 10.0 0.3 1.8 2 0 0 2 2 2 0 Tweety ATP1G1_PLM_MAT8 PF02038.11 CBZ22984.1 - 4.3 6.4 7.4 0.26 10.3 0.9 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Exo_endo_phos PF03372.18 CBZ22985.1 - 7.2e-11 42.4 0.3 1.2e-10 41.7 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kinesin PF00225.18 CBZ22986.1 - 1.9e-94 316.1 0.0 2.6e-94 315.6 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain ALMS_motif PF15309.1 CBZ22986.1 - 0.029 14.2 0.4 0.029 14.2 0.3 1.8 2 0 0 2 2 2 0 ALMS motif SAM_1 PF00536.25 CBZ22986.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) GYF PF02213.11 CBZ22987.1 - 0.0014 18.1 0.3 0.0024 17.3 0.2 1.4 1 0 0 1 1 1 1 GYF domain Rotamase_3 PF13616.1 CBZ22987.1 - 0.077 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain Rotamase PF00639.16 CBZ22987.1 - 0.093 13.4 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain CPSase_L_D2 PF02786.12 CBZ22988.1 - 6.6e-77 257.5 0.5 1.2e-76 256.6 0.3 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBZ22988.1 - 8.2e-40 135.3 0.8 3.2e-39 133.4 0.1 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBZ22988.1 - 1.9e-34 117.8 0.0 5.7e-34 116.3 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBZ22988.1 - 6.8e-18 64.0 3.7 6.8e-18 64.0 2.6 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CBZ22988.1 - 6e-14 52.1 0.0 4.5e-13 49.3 0.1 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBZ22988.1 - 1.7e-10 40.1 0.5 2.6e-10 39.5 0.3 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CBZ22988.1 - 2.3e-08 33.5 0.7 7.7e-08 31.8 0.2 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CBZ22988.1 - 3.2e-08 33.1 1.0 5.1e-05 22.8 0.0 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 CBZ22988.1 - 2.9e-06 26.8 0.3 7.2e-06 25.5 0.2 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CBZ22988.1 - 0.00041 20.2 0.1 0.00073 19.4 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 CBZ22988.1 - 0.00071 19.8 1.8 0.11 12.8 0.1 2.7 2 1 1 3 3 2 1 HlyD family secretion protein ATPgrasp_ST PF14397.1 CBZ22988.1 - 0.0029 16.7 0.0 0.0061 15.6 0.0 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GARS_A PF01071.14 CBZ22988.1 - 0.0039 16.7 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 CBZ22988.1 - 0.042 13.5 1.1 0.1 12.3 0.8 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein Remorin_C PF03763.8 CBZ22989.1 - 1.1 8.8 13.3 2.8 7.5 9.1 1.7 1 1 0 1 1 1 0 Remorin, C-terminal region BSD PF03909.12 CBZ22990.1 - 5.9e-10 38.7 0.0 1.1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 BSD domain Thymidylate_kin PF02223.12 CBZ22992.1 - 1.2e-33 116.0 0.0 1.4e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 CBZ22992.1 - 9.3e-06 25.5 0.1 2.1e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ22992.1 - 0.0016 18.1 0.4 0.0016 18.1 0.3 2.3 3 1 0 3 3 3 1 Part of AAA domain AAA_18 PF13238.1 CBZ22992.1 - 0.0016 18.7 0.2 0.012 15.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 CBZ22992.1 - 0.0037 16.8 0.0 0.0069 16.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 CBZ22992.1 - 0.0049 16.8 0.2 0.0092 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBZ22992.1 - 0.0065 16.6 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CBZ22992.1 - 0.016 14.1 0.0 0.022 13.7 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CBZ22992.1 - 0.017 14.7 2.1 0.031 13.8 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 CBZ22992.1 - 0.024 15.4 0.1 0.042 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CBZ22992.1 - 0.053 13.7 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Glyco_transf_11 PF01531.11 CBZ22993.1 - 1.4e-11 44.0 0.1 5.3e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 11 Glutaredoxin PF00462.19 CBZ22994.1 - 1.8e-17 63.0 0.3 4e-17 61.9 0.1 1.7 2 0 0 2 2 2 1 Glutaredoxin LSM PF01423.17 CBZ22999.1 - 3.2e-08 33.0 0.0 4e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain Voltage_CLC PF00654.15 CBZ23001.1 - 1.6e-88 297.0 35.2 2.7e-88 296.3 20.5 2.2 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 CBZ23001.1 - 8e-07 28.7 0.0 0.0012 18.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain cwf21 PF08312.7 CBZ23002.1 - 0.0036 17.1 0.1 0.0036 17.1 0.1 2.5 2 0 0 2 2 2 1 cwf21 domain Stathmin PF00836.14 CBZ23002.1 - 0.56 9.8 7.9 0.047 13.3 1.8 1.9 2 1 0 2 2 2 0 Stathmin family LMWPc PF01451.16 CBZ23003.1 - 2.8e-09 37.4 0.0 4.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF1771 PF08590.5 CBZ23004.1 - 1.8e-15 56.7 0.2 1.8e-15 56.7 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.11 CBZ23004.1 - 9.3e-12 44.2 0.1 0.00019 20.8 0.0 4.2 4 0 0 4 4 4 3 CUE domain Smr PF01713.16 CBZ23004.1 - 3.9e-10 39.7 0.6 1e-09 38.4 0.4 1.8 1 0 0 1 1 1 1 Smr domain UBA PF00627.26 CBZ23004.1 - 4.6e-09 35.8 0.1 1.2e-05 24.9 0.1 3.0 3 0 0 3 3 3 2 UBA/TS-N domain zf-CCCH PF00642.19 CBZ23004.1 - 9.9 5.9 22.2 0.81 9.4 0.6 4.1 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pro_isomerase PF00160.16 CBZ23005.1 - 6.4e-36 123.8 0.0 9.5e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SNF2_N PF00176.18 CBZ23007.1 - 1.1e-50 172.1 0.0 1.7e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ23007.1 - 5.2e-13 48.6 0.0 1.2e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ23007.1 - 0.00018 21.0 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ23007.1 - 0.0024 17.7 0.0 0.033 14.0 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CBZ23007.1 - 0.28 9.9 0.0 2.2 7.0 0.0 2.1 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Beta_helix PF13229.1 CBZ23008.1 - 1.4e-11 44.3 0.4 2.8e-11 43.4 0.3 1.5 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 CBZ23008.1 - 2.2e-06 27.0 0.0 3.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Enkurin PF13864.1 CBZ23009.1 - 6.3e-20 71.1 8.6 6.3e-20 71.1 6.0 1.7 2 0 0 2 2 2 1 Calmodulin-binding TBPIP PF07106.8 CBZ23009.1 - 0.25 10.8 3.2 0.48 9.9 2.2 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Thioredoxin PF00085.15 CBZ23010.1 - 5.7e-21 74.1 0.0 6.2e-21 74.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CBZ23010.1 - 2.2e-05 24.6 0.3 0.00013 22.1 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ23010.1 - 6.8e-05 22.9 0.3 0.0029 17.6 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 CBZ23010.1 - 0.023 14.4 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family HyaE PF07449.6 CBZ23010.1 - 0.026 14.3 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 CBZ23010.1 - 0.045 13.7 0.1 0.076 13.0 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.11 CBZ23010.1 - 0.063 11.9 0.0 0.066 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin DPM3 PF08285.6 CBZ23010.1 - 0.079 12.8 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Glutaredoxin PF00462.19 CBZ23010.1 - 0.15 12.0 0.2 0.32 11.0 0.2 1.6 1 0 0 1 1 1 0 Glutaredoxin PseudoU_synth_2 PF00849.17 CBZ23011.1 - 5.3e-21 75.1 0.0 1.8e-20 73.4 0.0 1.8 2 0 0 2 2 2 1 RNA pseudouridylate synthase Cmc1 PF08583.5 CBZ23012.1 - 7.7e-06 25.5 2.8 1.2e-05 24.9 2.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like 4F5 PF04419.9 CBZ23013.1 - 3.8e-13 49.9 8.7 3.8e-13 49.9 6.1 1.8 2 0 0 2 2 2 1 4F5 protein family WLM PF08325.5 CBZ23013.1 - 0.93 9.3 4.1 0.93 9.3 2.8 1.0 1 0 0 1 1 1 0 WLM domain DHHA2 PF02833.9 CBZ23014.1 - 4.2e-22 78.6 0.0 1.6e-21 76.7 0.0 1.9 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.15 CBZ23014.1 - 1.2e-11 44.3 0.0 9.6e-11 41.5 0.0 2.1 1 1 0 1 1 1 1 DHH family WD40 PF00400.27 CBZ23016.1 - 6.2e-11 41.7 12.8 8.2e-06 25.5 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat SPC25 PF06703.6 CBZ23017.1 - 0.043 13.4 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) MPC PF03650.8 CBZ23018.1 - 7.1e-14 51.7 0.4 8.3e-14 51.5 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Mst1_SARAH PF11629.3 CBZ23019.1 - 0.3 10.9 1.7 0.51 10.2 0.1 1.9 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 MCPVI PF02993.9 CBZ23019.1 - 0.46 10.6 3.3 0.62 10.1 2.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Activator-TraM PF11657.3 CBZ23020.1 - 2.6 7.5 5.6 2.2 7.7 2.2 2.0 1 1 1 2 2 2 0 Transcriptional activator TraM DUF605 PF04652.11 CBZ23020.1 - 6 6.1 11.2 8.6 5.6 7.8 1.2 1 0 0 1 1 1 0 Vta1 like DUF788 PF05620.6 CBZ23022.1 - 4.4e-36 124.3 0.0 5.2e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Dymeclin PF09742.4 CBZ23023.1 - 4.4e-63 213.5 0.0 5.8e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.2 CBZ23023.1 - 0.0046 14.7 0.1 0.92 7.1 0.0 2.2 2 0 0 2 2 2 2 High-temperature-induced dauer-formation protein DUF1664 PF07889.7 CBZ23024.1 - 0.13 12.0 0.8 0.29 10.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_S7e PF01251.13 CBZ23026.1 - 5.1e-70 234.8 4.7 5.9e-70 234.6 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e zf-UBP PF02148.14 CBZ23027.1 - 6.7e-11 42.1 9.6 6.7e-11 42.1 6.6 2.2 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 CBZ23027.1 - 7.2e-08 32.1 8.9 7.2e-08 32.1 6.2 3.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBZ23027.1 - 4.4e-05 23.0 16.7 0.00021 20.9 2.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ23027.1 - 7.2e-05 22.8 1.3 7.2e-05 22.8 0.9 2.6 3 0 0 3 3 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBZ23027.1 - 0.0028 17.3 7.1 0.0028 17.3 4.9 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBZ23027.1 - 0.0029 17.5 8.5 0.0029 17.5 5.9 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2852 PF11014.3 CBZ23027.1 - 0.0042 17.0 1.1 3.3 7.7 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF2852) zf-C3HC4 PF00097.20 CBZ23027.1 - 0.013 15.1 8.3 0.013 15.1 5.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RecR PF02132.10 CBZ23027.1 - 0.033 13.6 3.2 0.97 8.9 0.4 3.1 2 0 0 2 2 2 0 RecR protein Baculo_PP31 PF05311.6 CBZ23027.1 - 1.9 7.7 5.2 0.23 10.6 0.6 1.6 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) zf-C3HC4_4 PF15227.1 CBZ23027.1 - 7.3 6.5 21.3 7 6.6 7.5 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF791 PF05631.9 CBZ23028.1 - 4.1e-12 45.4 8.4 3.7e-07 29.1 0.8 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF791) Isochorismatase PF00857.15 CBZ23029.1 - 2.1e-23 83.1 0.0 2.5e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AMP-binding PF00501.23 CBZ23031.1 - 7.4e-85 284.8 0.1 1.1e-84 284.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Beta_elim_lyase PF01212.16 CBZ23032.1 - 1.6e-39 135.8 0.0 2e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CBZ23032.1 - 3.9e-09 35.7 0.0 5.4e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CBZ23032.1 - 1.8e-08 33.7 0.0 2.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II AMP-binding PF00501.23 CBZ23033.1 - 4.7e-91 305.2 0.0 6.8e-91 304.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 CBZ23034.1 - 7.9e-76 255.0 0.4 1.4e-75 254.2 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding PF00501.23 CBZ23036.1 - 4.4e-87 292.1 0.2 6.7e-87 291.5 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF4476 PF14771.1 CBZ23036.1 - 0.036 14.0 0.1 0.073 13.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) PGDYG PF14083.1 CBZ23036.1 - 0.051 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 PGDYG protein AMP-binding PF00501.23 CBZ23037.1 - 1.8e-40 138.6 1.6 9.1e-23 80.3 0.1 3.7 3 1 0 3 3 3 3 AMP-binding enzyme eIF3g PF12353.3 CBZ23039.1 - 0.0019 18.0 4.4 0.25 11.2 0.4 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.1 CBZ23039.1 - 0.0026 17.4 9.3 0.0049 16.5 1.0 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.18 CBZ23039.1 - 0.14 12.1 14.5 0.13 12.2 1.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zinc-ribbons_6 PF07191.7 CBZ23039.1 - 0.46 10.3 4.9 11 5.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbons PRP3 PF08572.5 CBZ23040.1 - 7e-26 90.9 0.0 1.2e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CBZ23040.1 - 1.3e-17 63.6 0.0 2.3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Mtc PF03820.12 CBZ23041.1 - 3.3e-115 383.9 0.1 3.7e-115 383.8 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier RNA_ligase PF09414.5 CBZ23043.1 - 4.2e-36 124.4 0.0 6.7e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 RNA ligase RabGAP-TBC PF00566.13 CBZ23044.1 - 5.5e-30 104.4 0.0 2.1e-14 53.5 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Asp_protease PF09668.5 CBZ23045.1 - 2.1e-56 188.8 0.3 2.8e-56 188.4 0.2 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CBZ23045.1 - 3.8e-09 36.2 0.0 8.1e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CBZ23045.1 - 1e-07 32.3 0.0 3e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Aspartyl protease UBA_4 PF14555.1 CBZ23045.1 - 4.1e-05 23.0 0.1 7.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain RVP_2 PF08284.6 CBZ23045.1 - 5.5e-05 23.1 0.0 8.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CBZ23045.1 - 0.0003 20.6 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease EF-hand_8 PF13833.1 CBZ23046.1 - 0.0023 17.4 0.0 0.0052 16.3 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair HSP70 PF00012.15 CBZ23048.1 - 1.2e-28 99.4 0.4 2.2e-24 85.3 0.1 4.0 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 CBZ23048.1 - 0.0032 16.1 1.4 0.0056 15.3 1.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein DUF3087 PF11286.3 CBZ23048.1 - 0.26 10.5 0.0 0.49 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) Peptidase_M16 PF00675.15 CBZ23049.1 - 1e-42 145.4 0.0 3.8e-42 143.5 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBZ23049.1 - 2e-17 63.4 0.0 7.1e-16 58.4 0.0 3.0 3 1 0 3 3 3 1 Peptidase M16 inactive domain ORC2 PF04084.9 CBZ23050.1 - 0.13 11.0 0.0 1.4 7.6 0.0 2.2 2 1 0 2 2 2 0 Origin recognition complex subunit 2 PLAC8 PF04749.12 CBZ23053.1 - 1.5e-13 51.1 8.6 2.6e-13 50.4 6.0 1.4 1 0 0 1 1 1 1 PLAC8 family ThiF PF00899.16 CBZ23055.1 - 2.8e-34 117.8 0.0 7.8e-34 116.4 0.0 1.8 1 1 0 1 1 1 1 ThiF family UBACT PF02134.16 CBZ23055.1 - 8.8e-18 63.6 0.0 3.2e-16 58.6 0.0 2.5 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CBZ23055.1 - 6.6e-07 28.6 0.8 1.2e-06 27.8 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CBZ23055.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 CBZ23055.1 - 0.015 14.3 0.1 0.19 10.6 0.1 2.1 1 1 1 2 2 2 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 CBZ23055.1 - 0.017 14.9 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CBZ23055.1 - 0.029 14.6 0.0 0.084 13.1 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 CBZ23055.1 - 0.056 13.8 0.3 0.12 12.7 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CC2D2AN-C2 PF15625.1 CBZ23057.1 - 9.7e-34 116.2 0.0 2.5e-33 114.9 0.0 1.8 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain DUF4478 PF14793.1 CBZ23057.1 - 0.025 14.1 0.0 0.071 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) C2 PF00168.25 CBZ23057.1 - 0.085 12.7 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 C2 domain DUF4336 PF14234.1 CBZ23058.1 - 0.17 11.0 0.7 1.5 7.9 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4336) Spt5_N PF11942.3 CBZ23058.1 - 3.7 8.2 14.7 0.22 12.1 3.7 2.3 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Pkinase PF00069.20 CBZ23059.1 - 1.2e-21 77.0 0.0 3.4e-10 39.5 0.0 3.8 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23059.1 - 0.011 14.8 0.0 0.062 12.3 0.0 2.1 3 0 0 3 3 3 0 Protein tyrosine kinase DEAD PF00270.24 CBZ23061.1 - 1.7e-39 135.0 0.1 6.4e-39 133.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ23061.1 - 5.6e-27 93.4 0.3 4.3e-26 90.5 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CBZ23061.1 - 4.9e-05 22.5 0.2 0.00015 20.9 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 CBZ23061.1 - 0.048 13.7 0.3 0.25 11.4 0.2 2.3 1 1 0 1 1 1 0 AAA domain DUF3128 PF11326.3 CBZ23062.1 - 0.0017 18.4 0.0 0.0033 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) zf-RING_3 PF14369.1 CBZ23063.1 - 0.054 13.4 1.6 0.17 11.9 1.1 1.8 1 0 0 1 1 1 0 zinc-finger Nudix_N_2 PF14803.1 CBZ23063.1 - 0.061 13.0 0.7 0.2 11.4 0.5 1.8 1 0 0 1 1 1 0 Nudix N-terminal zf-C2H2_6 PF13912.1 CBZ23063.1 - 0.068 13.0 0.7 0.068 13.0 0.5 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger CpXC PF14353.1 CBZ23063.1 - 0.14 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 CpXC protein zf-C2H2_4 PF13894.1 CBZ23063.1 - 0.43 11.0 3.5 1.8 9.1 2.4 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger BK_channel_a PF03493.13 CBZ23064.1 - 3.5e-20 71.8 0.0 6.8e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 CBZ23064.1 - 9.4e-12 44.4 5.6 9.4e-12 44.4 3.9 2.1 2 0 0 2 2 2 1 Ion channel Ion_trans_2 PF07885.11 CBZ23065.1 - 5.7e-11 41.9 5.7 1.9e-10 40.2 3.9 1.9 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.13 CBZ23065.1 - 2.2e-08 33.9 0.0 1.1e-05 25.3 0.0 2.6 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Peptidase_M3 PF01432.15 CBZ23066.1 - 6e-26 91.4 0.0 7e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Cyt-b5 PF00173.23 CBZ23069.1 - 3.6e-43 145.2 1.5 4.3e-21 74.5 0.1 2.4 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Xpo1 PF08389.7 CBZ23076.1 - 4.2e-25 88.3 0.4 2.6e-23 82.5 0.1 2.9 2 0 0 2 2 2 2 Exportin 1-like protein PI3_PI4_kinase PF00454.22 CBZ23077.1 - 4.8e-37 127.6 0.0 1e-36 126.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CBZ23077.1 - 2.3e-06 26.9 0.0 5.3e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 FATC domain zf-met PF12874.2 CBZ23078.1 - 0.00021 21.3 0.2 0.00047 20.2 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBZ23078.1 - 0.0036 17.3 0.2 0.0087 16.1 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Ank_4 PF13637.1 CBZ23079.1 - 3.9e-09 36.7 0.1 0.00012 22.5 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBZ23079.1 - 8.8e-08 32.3 0.0 5.7e-07 29.7 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) zf-C3HC4_3 PF13920.1 CBZ23079.1 - 2.3e-06 27.1 7.2 4.4e-06 26.2 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_5 PF13857.1 CBZ23079.1 - 5.2e-06 26.5 0.0 4.4e-05 23.5 0.0 2.7 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 CBZ23079.1 - 0.0014 18.3 2.1 0.095 12.5 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 CBZ23079.1 - 0.013 15.7 0.1 0.17 12.1 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeat Vps51 PF08700.6 CBZ23080.1 - 1.6e-09 37.4 0.1 5.4e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Galactosyl_T PF01762.16 CBZ23081.1 - 0.017 14.7 0.1 0.053 13.1 0.0 1.9 2 0 0 2 2 2 0 Galactosyltransferase Galactosyl_T PF01762.16 CBZ23082.1 - 0.013 15.1 0.0 0.047 13.2 0.0 1.9 2 0 0 2 2 2 0 Galactosyltransferase Galactosyl_T PF01762.16 CBZ23083.1 - 0.16 11.5 0.0 0.16 11.5 0.0 2.8 4 0 0 4 4 4 0 Galactosyltransferase Galactosyl_T PF01762.16 CBZ23084.1 - 0.0055 16.3 0.1 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 Galactosyltransferase MscS_TM PF12794.2 CBZ23084.1 - 0.38 9.3 0.9 0.42 9.1 0.0 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 GlcNAc PF11397.3 CBZ23085.1 - 6.3e-117 390.5 0.0 8.5e-117 390.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) GlcNAc PF11397.3 CBZ23086.1 - 5.7e-07 28.9 0.1 0.007 15.5 0.0 2.8 3 0 0 3 3 3 2 Glycosyltransferase (GlcNAc) Ras PF00071.17 CBZ23087.1 - 2.5e-53 179.7 0.1 2.9e-53 179.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ23087.1 - 2.7e-22 79.5 0.0 4.2e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ23087.1 - 8e-15 54.5 0.0 1e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ23087.1 - 1.8e-06 27.2 0.1 2.3e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ23087.1 - 1.6e-05 24.4 0.1 4.1e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBZ23087.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBZ23087.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ23087.1 - 0.026 13.8 0.0 1.5 8.1 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.12 CBZ23087.1 - 0.034 13.6 0.0 0.08 12.4 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CBZ23087.1 - 0.077 12.4 0.2 7.7 5.9 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2464 PF10240.4 CBZ23089.1 - 0.00082 18.7 0.2 0.001 18.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2464) K_channel_TID PF07941.6 CBZ23089.1 - 1.9 8.7 16.5 1 9.5 10.0 1.6 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Pkinase PF00069.20 CBZ23090.1 - 1.2e-47 162.2 0.0 6.2e-47 159.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23090.1 - 1.5e-29 102.8 0.0 2e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23090.1 - 2.9e-08 33.0 0.0 4.8e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CBZ23090.1 - 0.23 10.2 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ABC2_membrane_3 PF12698.2 CBZ23091.1 - 1.1e-56 192.4 30.3 2.7e-35 122.0 6.8 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 CBZ23091.1 - 2.3e-50 170.4 0.0 1.4e-25 90.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBZ23091.1 - 1.3e-18 67.9 0.1 1.8e-05 24.8 0.0 5.3 4 1 0 4 4 4 3 AAA domain AAA_23 PF13476.1 CBZ23091.1 - 1.4e-07 32.0 0.1 0.00052 20.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBZ23091.1 - 2.4e-06 26.9 0.1 0.0036 16.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CBZ23091.1 - 0.00029 20.1 0.0 5.6 6.1 0.1 3.5 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBZ23091.1 - 0.00031 19.9 0.0 0.0075 15.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane PF01061.19 CBZ23091.1 - 0.00045 19.4 49.9 0.01 15.0 15.3 3.7 4 1 0 4 4 4 2 ABC-2 type transporter AAA_25 PF13481.1 CBZ23091.1 - 0.0032 16.8 0.6 10 5.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 CBZ23091.1 - 0.0047 16.3 0.2 2.7 7.3 0.3 2.9 3 0 0 3 3 3 1 AAA-like domain AAA_15 PF13175.1 CBZ23091.1 - 0.014 14.4 0.0 5.9 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain UPF0079 PF02367.12 CBZ23091.1 - 0.034 13.7 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 CBZ23091.1 - 0.049 13.0 0.7 0.59 9.5 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Dynamin_N PF00350.18 CBZ23091.1 - 0.12 12.1 0.0 7.5 6.3 0.0 2.9 3 0 0 3 3 3 0 Dynamin family Miro PF08477.8 CBZ23091.1 - 0.13 12.7 0.0 8.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 CBZ23091.1 - 0.16 11.9 0.1 1.3 8.9 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.12 CBZ23091.1 - 0.22 11.3 1.2 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 CBZ23091.1 - 0.24 11.5 0.2 32 4.7 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.1 CBZ23091.1 - 1.6 8.6 7.1 12 5.8 0.0 4.1 4 0 0 4 4 4 0 AAA domain AAA_13 PF13166.1 CBZ23091.1 - 5.1 5.4 1.6 21 3.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain SNAP PF14938.1 CBZ23092.1 - 1.3e-12 47.4 16.0 6.1e-10 38.7 5.2 3.1 3 0 0 3 3 3 2 Soluble NSF attachment protein, SNAP Epimerase PF01370.16 CBZ23092.1 - 0.052 12.9 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TPR_2 PF07719.12 CBZ23092.1 - 0.84 9.7 0.0 0.84 9.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ23092.1 - 1.1 9.2 15.5 1.7 8.6 1.2 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat RNase_PH PF01138.16 CBZ23093.1 - 9.4e-18 64.7 0.0 1.9e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 CBM_19 PF03427.8 CBZ23093.1 - 0.19 11.4 5.7 0.043 13.5 1.2 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) Glyco_transf_10 PF00852.14 CBZ23094.1 - 4e-08 32.2 0.0 7.7e-08 31.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) UAA PF08449.6 CBZ23095.1 - 3.8e-17 62.1 15.0 1.3e-11 43.9 3.4 3.9 4 0 0 4 4 4 2 UAA transporter family TPT PF03151.11 CBZ23095.1 - 2.2e-07 30.6 5.8 2.2e-07 30.6 4.0 2.5 3 0 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 CBZ23095.1 - 0.0007 19.6 3.8 0.0007 19.6 2.6 2.7 4 0 0 4 4 4 1 EamA-like transporter family TMEM173 PF15009.1 CBZ23095.1 - 0.26 10.0 0.0 0.56 8.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 173 Pkinase PF00069.20 CBZ23097.1 - 8.1e-53 179.2 0.0 1e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23097.1 - 3.8e-20 72.0 0.0 5e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ23097.1 - 2.5e-06 27.3 1.6 0.00033 20.4 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ23097.1 - 0.00081 18.7 0.1 0.0013 18.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family PCI PF01399.22 CBZ23098.1 - 1.5e-11 44.5 0.2 4e-11 43.1 0.1 1.8 1 0 0 1 1 1 1 PCI domain TPR_19 PF14559.1 CBZ23098.1 - 0.0011 19.3 0.6 3.4 8.0 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DDRGK PF09756.4 CBZ23098.1 - 0.1 12.0 0.1 0.1 12.0 0.1 2.0 2 0 0 2 2 2 0 DDRGK domain TPR_16 PF13432.1 CBZ23098.1 - 0.77 10.5 0.0 0.77 10.5 0.0 4.3 5 1 1 6 6 6 0 Tetratricopeptide repeat FtsJ PF01728.14 CBZ23099.1 - 1.3e-62 210.9 0.0 1.7e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.21 CBZ23100.1 - 2.5e-40 137.1 0.0 2.9e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ23100.1 - 0.00013 21.7 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Gly-zipper_OmpA PF13436.1 CBZ23102.1 - 0.013 15.1 2.0 0.013 15.1 1.4 7.9 7 2 2 9 9 9 0 Glycine-zipper containing OmpA-like membrane domain zf-met PF12874.2 CBZ23102.1 - 0.17 12.1 3.5 0.3 11.3 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBZ23102.1 - 0.31 11.2 2.6 0.48 10.6 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4131 PF13567.1 CBZ23103.1 - 0.018 14.4 0.3 0.018 14.4 0.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) ESSS PF10183.4 CBZ23103.1 - 0.046 14.1 0.0 0.62 10.4 0.0 2.8 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PSI PF01437.20 CBZ23103.1 - 3.4 7.9 10.3 0.72 10.0 2.9 2.6 2 1 0 2 2 2 0 Plexin repeat Rhomboid PF01694.17 CBZ23104.1 - 7.4e-08 32.5 6.9 0.00018 21.5 0.5 2.7 3 0 0 3 3 3 2 Rhomboid family NodS PF05401.6 CBZ23106.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) Porin_3 PF01459.17 CBZ23107.1 - 1.4e-07 31.0 0.0 2.6e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic porin SLX9 PF15341.1 CBZ23109.1 - 0.00039 20.8 9.9 0.0065 16.8 6.9 2.5 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 Gly_kinase PF02595.10 CBZ23111.1 - 8.1e-27 93.9 18.6 1.5e-06 27.1 0.1 7.2 7 0 0 7 7 7 7 Glycerate kinase family Kinocilin PF15033.1 CBZ23115.1 - 0.081 12.4 1.0 0.26 10.8 0.3 2.0 2 0 0 2 2 2 0 Kinocilin protein Pkinase PF00069.20 CBZ23118.1 - 3.3e-58 196.8 0.0 1.1e-57 195.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23118.1 - 1.1e-35 122.9 0.0 1.6e-30 106.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23118.1 - 3.4e-05 22.9 0.0 0.00017 20.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CBZ23118.1 - 0.00073 18.9 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBZ23118.1 - 0.0025 17.6 1.6 0.0066 16.2 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ23118.1 - 0.039 13.0 0.1 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HemY_N PF07219.8 CBZ23118.1 - 1.1 8.8 3.9 0.38 10.3 0.3 2.0 2 0 0 2 2 2 0 HemY protein N-terminus Snf7 PF03357.16 CBZ23119.1 - 0.011 15.1 4.3 0.019 14.3 3.0 1.3 1 0 0 1 1 1 0 Snf7 DUF2317 PF10079.4 CBZ23119.1 - 1.3 7.5 0.6 2.2 6.7 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) TPR_11 PF13414.1 CBZ23120.1 - 1e-14 53.9 7.5 4.6e-07 29.3 0.9 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBZ23120.1 - 8.9e-09 34.5 3.5 1.8e-07 30.4 0.5 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ23120.1 - 4.2e-07 29.3 9.1 1.4e-06 27.7 0.7 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ23120.1 - 2.6e-06 26.8 0.6 8.1e-06 25.2 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ23120.1 - 0.00022 20.7 3.2 0.13 12.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ23120.1 - 0.011 15.5 0.5 0.011 15.5 0.4 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ23120.1 - 0.012 16.3 1.2 0.012 16.3 0.9 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ23120.1 - 0.029 14.9 6.9 0.16 12.6 0.1 4.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ23120.1 - 2.1 8.3 9.4 4.5 7.2 2.1 3.2 2 1 2 4 4 4 0 Tetratricopeptide repeat ARPC4 PF05856.7 CBZ23121.1 - 7.6e-59 197.9 0.0 8.4e-59 197.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UBN2 PF14223.1 CBZ23122.1 - 0.24 11.2 7.7 0.19 11.5 0.4 2.6 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF940 PF06082.6 CBZ23122.1 - 0.26 9.8 2.7 0.33 9.4 1.9 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) DUF3584 PF12128.3 CBZ23122.1 - 0.39 7.9 21.8 0.51 7.6 15.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Nsp1_C PF05064.8 CBZ23122.1 - 1.1 8.9 15.0 0.068 12.8 1.4 3.0 2 1 0 2 2 2 0 Nsp1-like C-terminal region FlaC_arch PF05377.6 CBZ23122.1 - 3.4 7.6 5.9 5.1 7.0 1.7 2.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 CBZ23122.1 - 3.4 7.2 21.4 0.066 12.7 2.8 3.3 2 2 0 2 2 2 0 Septum formation initiator CENP-H PF05837.7 CBZ23122.1 - 3.5 7.8 18.7 0.78 9.9 4.5 2.4 2 1 0 2 2 2 0 Centromere protein H (CENP-H) LMBR1 PF04791.11 CBZ23122.1 - 3.9 5.9 7.9 1.8 7.0 3.8 1.5 1 1 1 2 2 2 0 LMBR1-like membrane protein DUF3373 PF11853.3 CBZ23122.1 - 6.2 5.2 5.6 7 5.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) Syntaxin PF00804.20 CBZ23122.1 - 6.8 6.9 16.2 5.3e+02 0.8 11.3 2.4 1 1 0 1 1 1 0 Syntaxin LLC1 PF14945.1 CBZ23122.1 - 8.6 6.7 7.6 6 7.1 0.3 3.1 2 1 1 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Spc7 PF08317.6 CBZ23122.1 - 9.5 4.7 20.4 0.63 8.6 3.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein WD40 PF00400.27 CBZ23123.1 - 0.0051 16.6 13.8 0.0096 15.7 0.7 4.8 5 1 0 5 5 5 3 WD domain, G-beta repeat Aldedh PF00171.17 CBZ23124.1 - 0.00064 18.1 1.1 0.084 11.1 0.0 2.5 3 0 0 3 3 3 2 Aldehyde dehydrogenase family LRR_4 PF12799.2 CBZ23125.1 - 4.4e-10 38.9 0.0 0.2 11.3 0.0 8.1 9 0 0 9 9 9 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ23125.1 - 1.3e-08 34.4 0.0 2.4 7.9 0.0 5.8 6 1 1 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 CBZ23125.1 - 0.00013 21.6 2.6 1.3e+02 3.1 0.0 8.4 9 1 1 10 10 10 0 Leucine Rich repeat LRR_7 PF13504.1 CBZ23125.1 - 7.1 7.3 18.0 89 3.9 0.0 8.3 10 0 0 10 10 10 0 Leucine rich repeat Nop14 PF04147.7 CBZ23127.1 - 1.5e-42 145.5 21.4 1.1e-30 106.3 0.4 3.0 2 1 1 3 3 3 3 Nop14-like family Mito_carr PF00153.22 CBZ23128.1 - 1.7e-29 101.3 3.0 2.6e-15 55.8 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein HR1 PF02185.11 CBZ23130.1 - 0.043 13.5 1.2 0.14 11.8 0.8 1.9 1 0 0 1 1 1 0 Hr1 repeat Reo_sigmaC PF04582.7 CBZ23131.1 - 1.1 8.3 26.7 0.4 9.7 2.4 4.7 2 1 3 6 6 6 0 Reovirus sigma C capsid protein AAA_2 PF07724.9 CBZ23132.1 - 2.6e-51 173.9 0.0 1.1e-48 165.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBZ23132.1 - 1.6e-24 86.6 0.5 4.1e-14 52.9 0.0 3.5 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CBZ23132.1 - 6.2e-22 77.3 0.8 1.8e-21 75.8 0.0 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CBZ23132.1 - 1.8e-17 63.3 0.1 5.3e-11 42.4 0.0 3.9 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ23132.1 - 2.2e-12 47.3 2.0 0.00027 20.9 0.0 4.5 3 3 0 4 4 4 3 AAA ATPase domain AAA_22 PF13401.1 CBZ23132.1 - 3e-10 40.3 3.7 0.00035 20.7 0.0 4.8 4 2 1 5 5 4 2 AAA domain AAA_17 PF13207.1 CBZ23132.1 - 1.5e-07 32.2 1.9 0.0077 17.0 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CBZ23132.1 - 2.9e-06 27.5 2.7 0.071 13.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 CBZ23132.1 - 1.4e-05 24.5 0.0 0.027 13.8 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein DNA_pol3_delta2 PF13177.1 CBZ23132.1 - 1.5e-05 24.7 0.4 0.0035 17.0 0.0 3.9 3 2 0 3 3 3 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 CBZ23132.1 - 1.9e-05 23.9 0.0 1 8.4 0.0 3.6 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBZ23132.1 - 3.4e-05 23.7 0.2 0.27 11.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 CBZ23132.1 - 4.3e-05 23.6 0.0 0.7 10.0 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_3 PF07726.6 CBZ23132.1 - 0.00021 20.8 0.0 0.4 10.2 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBZ23132.1 - 0.00022 20.6 0.0 2.3 7.6 0.0 3.8 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CBZ23132.1 - 0.00025 20.5 0.0 0.16 11.4 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 CBZ23132.1 - 0.00041 19.4 0.2 0.86 8.5 0.0 3.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CBZ23132.1 - 0.00049 19.8 0.1 0.049 13.2 0.0 3.4 3 0 0 3 3 3 1 NACHT domain MobB PF03205.9 CBZ23132.1 - 0.00064 19.4 0.0 0.23 11.1 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CBZ23132.1 - 0.00084 19.0 0.0 0.098 12.4 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain Ribosomal_S7 PF00177.16 CBZ23132.1 - 0.00091 18.8 0.0 0.0038 16.8 0.0 2.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e AAA_28 PF13521.1 CBZ23132.1 - 0.004 17.1 0.5 1.4 8.8 0.0 3.3 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.7 CBZ23132.1 - 0.0052 15.8 0.0 0.6 9.1 0.0 2.9 2 1 0 2 2 2 1 Zeta toxin SRP54 PF00448.17 CBZ23132.1 - 0.0055 16.1 0.1 0.93 8.8 0.0 3.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain DUF815 PF05673.8 CBZ23132.1 - 0.0082 15.0 0.3 0.2 10.5 0.0 3.2 4 1 0 4 4 4 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 CBZ23132.1 - 0.012 15.2 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CBZ23132.1 - 0.013 14.6 0.0 2.3 7.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DEAD PF00270.24 CBZ23132.1 - 0.017 14.6 0.2 8.6 5.8 0.0 3.4 3 0 0 3 3 3 0 DEAD/DEAH box helicase NTPase_1 PF03266.10 CBZ23132.1 - 0.019 14.6 0.3 3.7 7.2 0.0 3.2 4 0 0 4 4 3 0 NTPase ABC_tran PF00005.22 CBZ23132.1 - 0.02 15.1 1.1 7.9 6.7 0.0 3.4 3 1 0 3 3 3 0 ABC transporter ResIII PF04851.10 CBZ23132.1 - 0.022 14.6 3.7 3.7 7.3 0.0 3.8 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit Torsin PF06309.6 CBZ23132.1 - 0.027 14.3 0.0 0.087 12.7 0.0 1.8 2 0 0 2 2 1 0 Torsin AAA_29 PF13555.1 CBZ23132.1 - 0.028 13.9 0.0 5.2 6.6 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.1 CBZ23132.1 - 0.032 14.0 0.0 7.1 6.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CBZ23132.1 - 0.045 14.2 0.2 0.43 11.0 0.0 2.7 3 0 0 3 3 2 0 Miro-like protein UPF0079 PF02367.12 CBZ23132.1 - 0.062 12.9 0.0 13 5.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 CBZ23132.1 - 0.076 12.9 0.0 1.9 8.4 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CBZ23132.1 - 0.093 12.2 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein V_ATPase_I PF01496.14 CBZ23132.1 - 0.24 9.2 7.4 0.34 8.7 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 CBZ23132.1 - 2.9 8.1 14.9 31 4.8 0.0 3.2 2 1 0 2 2 1 0 AAA domain Peptidase_M3 PF01432.15 CBZ23135.1 - 1.6e-135 452.7 0.0 2.1e-135 452.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 CBZ23135.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like LRR_4 PF12799.2 CBZ23136.1 - 2.6e-67 221.5 1.8 0.00044 19.7 0.0 16.9 13 3 4 18 18 18 18 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ23136.1 - 8.7e-18 63.8 21.4 0.025 14.3 0.1 11.9 8 3 4 13 13 13 7 Leucine rich repeat LRR_1 PF00560.28 CBZ23136.1 - 2.1e-17 60.4 30.8 4.5 7.6 0.0 22.8 28 0 0 28 28 28 3 Leucine Rich Repeat LRR_5 PF13306.1 CBZ23136.1 - 0.0001 22.0 6.1 7.2 6.3 0.0 6.1 5 1 1 6 6 6 2 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBZ23136.1 - 0.00015 21.3 26.2 9.3 6.9 0.2 14.7 18 0 0 18 18 18 1 Leucine rich repeat HJURP_mid PF12346.3 CBZ23136.1 - 0.016 15.3 0.0 9.7 6.3 0.0 3.4 2 1 0 2 2 2 0 Holliday junction recognition protein-associated repeat zf-RING_2 PF13639.1 CBZ23136.1 - 2.8 7.8 19.0 16 5.4 13.2 2.5 1 0 0 1 1 1 0 Ring finger domain 2-Hacid_dh_C PF02826.14 CBZ23138.1 - 1.7e-54 183.6 0.1 2.4e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CBZ23138.1 - 1.7e-32 111.7 0.0 2.1e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CBZ23138.1 - 1.6e-06 28.0 0.3 6e-06 26.2 0.2 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 CBZ23138.1 - 0.00076 19.3 0.6 0.0016 18.3 0.4 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 CBZ23138.1 - 0.0033 16.8 0.1 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 ACT domain IlvN PF07991.7 CBZ23138.1 - 0.021 14.2 0.1 0.051 12.9 0.0 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 CBZ23138.1 - 0.03 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.9 CBZ23138.1 - 0.49 9.7 2.9 0.96 8.7 1.7 1.7 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aminotran_5 PF00266.14 CBZ23139.1 - 1.6e-19 69.9 0.0 1.8e-19 69.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Met_10 PF02475.11 CBZ23140.1 - 6.2e-41 140.1 0.0 1.3e-37 129.4 0.0 2.1 2 0 0 2 2 2 2 Met-10+ like-protein Methyltransf_26 PF13659.1 CBZ23140.1 - 3.7e-08 33.4 0.1 1.3e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ23140.1 - 1.4e-05 25.6 0.0 2.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ23140.1 - 2.3e-05 23.8 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 CBZ23140.1 - 3.4e-05 23.4 0.0 5.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 CBZ23140.1 - 0.0001 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CBZ23140.1 - 0.0032 16.2 0.0 0.0055 15.4 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase UPF0020 PF01170.13 CBZ23140.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ATLF PF07737.6 CBZ23140.1 - 0.15 11.3 0.0 0.35 10.2 0.0 1.5 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain Acyltransferase PF01553.16 CBZ23142.1 - 5.8e-14 51.6 0.0 2.9e-13 49.3 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase HopW1-1 PF15457.1 CBZ23142.1 - 0.18 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA DNA_primase_lrg PF04104.9 CBZ23143.1 - 1.3e-77 260.6 0.0 1.7e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit FAM220 PF15487.1 CBZ23143.1 - 0.007 15.7 0.7 0.053 12.8 0.1 2.1 2 0 0 2 2 2 1 FAM220 family CtaG_Cox11 PF04442.9 CBZ23144.1 - 1.4e-41 141.8 0.0 1.5e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 CH PF00307.26 CBZ23145.1 - 0.059 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Calponin homology (CH) domain LRR_4 PF12799.2 CBZ23146.1 - 7.3e-17 60.5 12.6 5.1e-06 25.9 0.3 4.6 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ23146.1 - 1.5e-10 40.6 14.1 0.00023 20.8 1.1 3.7 4 0 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 CBZ23146.1 - 2.6e-06 27.1 3.2 0.00025 20.6 0.3 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 CBZ23146.1 - 0.00034 20.2 16.8 0.79 9.9 0.1 6.8 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 CBZ23146.1 - 0.0013 18.6 14.6 0.33 11.3 0.0 6.5 7 0 0 7 7 6 1 Leucine rich repeat DUF4530 PF15039.1 CBZ23146.1 - 0.0044 16.9 2.6 0.021 14.7 1.8 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4530) LRR_6 PF13516.1 CBZ23146.1 - 0.062 13.3 9.3 12 6.3 0.0 5.5 5 0 0 5 5 5 0 Leucine Rich repeat LMP PF04778.7 CBZ23146.1 - 0.1 12.3 0.2 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 LMP repeated region Filament PF00038.16 CBZ23146.1 - 0.28 10.5 12.2 0.76 9.1 8.4 1.7 1 1 0 1 1 1 0 Intermediate filament protein CR6_interact PF10147.4 CBZ23146.1 - 0.37 10.0 6.9 0.35 10.1 3.5 1.8 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 TMF_TATA_bd PF12325.3 CBZ23146.1 - 0.43 10.3 9.7 1 9.1 6.7 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Tup_N PF08581.5 CBZ23146.1 - 0.51 10.5 5.5 3.7 7.7 0.7 2.5 2 0 0 2 2 2 0 Tup N-terminal Spc7 PF08317.6 CBZ23146.1 - 0.78 8.3 6.6 1.3 7.6 4.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Prefoldin_2 PF01920.15 CBZ23146.1 - 2.9 7.7 7.5 0.59 9.9 1.1 2.4 2 0 0 2 2 2 0 Prefoldin subunit APG6 PF04111.7 CBZ23146.1 - 8.7 5.2 10.5 14 4.5 7.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Acetyltransf_1 PF00583.19 CBZ23147.1 - 1.2e-08 34.9 0.0 1.8e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ23147.1 - 6e-06 26.3 0.1 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ23147.1 - 0.00061 19.6 0.0 0.0012 18.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4257 PF14074.1 CBZ23147.1 - 0.025 14.2 0.0 0.057 13.0 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4257) DUF4558 PF15104.1 CBZ23148.1 - 8.8e-06 25.5 3.0 1.2e-05 25.1 2.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4558) ABC_tran PF00005.22 CBZ23150.1 - 8.7e-47 158.8 4.8 1.4e-22 80.4 0.0 3.7 4 0 0 4 4 3 2 ABC transporter ABC_tran_2 PF12848.2 CBZ23150.1 - 4.2e-24 84.1 4.1 4.2e-24 84.1 2.9 3.1 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 CBZ23150.1 - 6.8e-19 68.9 6.8 0.0001 22.4 0.3 4.6 4 1 1 5 5 5 4 AAA domain SMC_N PF02463.14 CBZ23150.1 - 4.2e-11 42.4 1.5 0.0035 16.5 0.1 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBZ23150.1 - 2.7e-08 33.2 0.3 0.0025 17.3 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CBZ23150.1 - 5.3e-08 33.7 0.0 0.00036 21.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBZ23150.1 - 5.1e-07 29.0 0.1 0.0058 15.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBZ23150.1 - 1.5e-06 28.3 1.4 0.015 15.2 0.1 3.1 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 CBZ23150.1 - 2e-06 27.7 0.0 0.1 12.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 CBZ23150.1 - 2.3e-06 26.9 8.2 0.52 9.2 0.0 5.1 3 1 1 5 5 5 2 AAA ATPase domain Miro PF08477.8 CBZ23150.1 - 7e-06 26.5 0.1 0.08 13.4 0.0 3.0 3 0 0 3 3 2 2 Miro-like protein AAA_33 PF13671.1 CBZ23150.1 - 3.3e-05 23.7 4.0 0.07 13.0 0.0 3.7 4 1 0 4 4 3 2 AAA domain NACHT PF05729.7 CBZ23150.1 - 5.8e-05 22.8 0.0 0.43 10.2 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.1 CBZ23150.1 - 0.00015 22.1 11.5 0.078 13.2 0.0 4.3 5 0 0 5 5 4 2 AAA domain AAA_28 PF13521.1 CBZ23150.1 - 0.00016 21.6 5.7 0.022 14.6 0.1 3.6 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 CBZ23150.1 - 0.00021 20.7 0.4 1.1 8.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CBZ23150.1 - 0.00022 21.3 1.5 0.26 11.4 0.1 3.5 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ23150.1 - 0.00061 20.0 2.0 0.11 12.8 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 CBZ23150.1 - 0.00068 19.2 1.2 0.92 9.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 CBZ23150.1 - 0.00077 19.6 0.1 0.76 9.9 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CBZ23150.1 - 0.001 18.7 0.2 0.92 9.2 0.0 3.1 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CBZ23150.1 - 0.0011 18.5 0.0 0.06 12.8 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 CBZ23150.1 - 0.0013 18.5 4.6 0.6 9.9 0.0 4.1 4 1 0 4 4 4 1 Dynamin family SbcCD_C PF13558.1 CBZ23150.1 - 0.0017 18.2 0.1 0.4 10.6 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 CBZ23150.1 - 0.0018 18.1 0.0 4.8 7.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 CBZ23150.1 - 0.0018 18.4 0.0 0.6 10.3 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 CBZ23150.1 - 0.0025 17.5 0.1 2.3 7.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) cobW PF02492.14 CBZ23150.1 - 0.012 15.0 0.1 0.34 10.3 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 CBZ23150.1 - 0.012 15.1 0.1 0.52 9.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 CBZ23150.1 - 0.013 15.0 1.6 1.9 7.9 0.0 3.0 2 1 1 3 3 3 0 FtsK/SpoIIIE family SRP54 PF00448.17 CBZ23150.1 - 0.019 14.3 0.2 4.9 6.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arch_ATPase PF01637.13 CBZ23150.1 - 0.022 14.4 0.4 4.7 6.8 0.0 3.3 3 0 0 3 3 3 0 Archaeal ATPase FeoB_N PF02421.13 CBZ23150.1 - 0.032 13.5 0.1 1.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Arf PF00025.16 CBZ23150.1 - 0.037 13.2 1.6 1.7 7.8 0.0 3.2 4 0 0 4 4 4 0 ADP-ribosylation factor family ATP_bind_1 PF03029.12 CBZ23150.1 - 0.72 9.3 4.1 17 4.8 0.1 3.2 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CBZ23150.1 - 0.73 9.2 8.7 3.2 7.0 0.1 3.7 4 1 0 4 4 4 0 AAA-like domain Septin PF00735.13 CBZ23150.1 - 2.6 6.9 8.6 2.4 7.0 0.0 3.3 4 0 0 4 4 4 0 Septin zf-C2H2_3 PF13878.1 CBZ23152.1 - 1.3e-11 43.8 0.0 3.4e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO zf-CCCH PF00642.19 CBZ23153.1 - 5e-08 32.4 8.7 7.9e-05 22.2 0.8 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 CBZ23153.1 - 2.7e-06 26.9 0.0 3.4e-05 23.3 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_UL87 PF03043.9 CBZ23153.1 - 0.063 11.6 0.1 0.085 11.2 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family zf-CCCH_2 PF14608.1 CBZ23153.1 - 2.4 8.3 8.9 6 7.0 1.5 2.8 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Aldedh PF00171.17 CBZ23154.1 - 7e-106 354.3 0.0 8.3e-106 354.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.20 CBZ23155.1 - 2.4e-41 141.6 0.0 3.2e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23155.1 - 1.3e-19 70.2 0.0 2.5e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ23155.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBZ23155.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 CBZ23155.1 - 0.084 11.8 0.0 0.19 10.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like AMP-binding PF00501.23 CBZ23157.1 - 1.2e-82 277.5 0.0 1.5e-82 277.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_L38e PF01781.13 CBZ23159.1 - 6.2e-31 105.9 3.8 7.4e-31 105.7 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Viral_Beta_CD PF04530.7 CBZ23160.1 - 0.041 14.0 0.3 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 Viral Beta C/D like family DUF3609 PF12259.3 CBZ23160.1 - 0.089 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Apolipoprotein PF01442.13 CBZ23161.1 - 5.4e-70 235.0 231.9 1e-24 87.2 38.7 9.2 2 1 6 8 8 8 4 Apolipoprotein A1/A4/E domain DUF3618 PF12277.3 CBZ23161.1 - 1.1e-22 79.7 196.5 0.0093 15.9 5.8 15.2 3 1 10 13 13 13 11 Protein of unknown function (DUF3618) Flg_hook PF02120.11 CBZ23161.1 - 1.6e-13 50.0 136.9 0.25 11.0 3.5 13.0 3 1 10 13 13 13 11 Flagellar hook-length control protein FliK FYVE PF01363.16 CBZ23161.1 - 8.1e-11 41.6 9.6 2e-10 40.4 6.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger GAS PF13851.1 CBZ23161.1 - 0.002 17.3 140.6 0.0081 15.3 10.6 9.2 2 1 8 11 11 11 7 Growth-arrest specific micro-tubule binding DUF1492 PF07374.6 CBZ23161.1 - 0.0047 17.0 51.4 17 5.5 0.2 12.2 2 1 10 12 12 12 0 Protein of unknown function (DUF1492) Borrelia_lipo_1 PF05714.6 CBZ23161.1 - 0.43 9.6 11.6 24 3.9 0.1 4.6 1 1 6 7 7 7 0 Borrelia burgdorferi virulent strain associated lipoprotein IBR PF01485.16 CBZ23161.1 - 0.68 9.8 5.4 2.3 8.1 3.8 1.9 1 0 0 1 1 1 0 IBR domain Myosin_tail_1 PF01576.14 CBZ23161.1 - 1.1 6.8 207.2 0.0042 14.9 84.1 4.2 2 1 2 4 4 4 0 Myosin tail Prefoldin_2 PF01920.15 CBZ23161.1 - 5 6.9 127.9 2.8 7.7 0.7 16.4 5 1 0 16 16 16 0 Prefoldin subunit DUF4206 PF13901.1 CBZ23162.1 - 2.7e-10 40.1 2.6 0.1 12.1 0.0 4.7 4 1 0 4 4 4 3 Domain of unknown function (DUF4206) DDRGK PF09756.4 CBZ23167.1 - 4.4e-26 91.4 24.9 1.7e-17 63.4 0.0 2.2 2 0 0 2 2 2 2 DDRGK domain FAM117 PF15388.1 CBZ23167.1 - 0.92 8.6 5.6 2 7.5 3.9 1.6 1 0 0 1 1 1 0 Protein Family FAM117 Pkinase PF00069.20 CBZ23168.1 - 6.1e-34 117.3 0.8 2.3e-24 85.9 0.0 4.4 5 0 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23168.1 - 1e-14 54.2 0.0 6.9e-13 48.2 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23168.1 - 0.00016 20.7 0.0 0.00032 19.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CBZ23168.1 - 0.43 9.3 0.0 0.73 8.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Grp1_Fun34_YaaH PF01184.14 CBZ23170.1 - 7.3e-37 126.7 15.0 9.6e-37 126.3 10.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Zn_Tnp_IS91 PF14319.1 CBZ23170.1 - 0.052 13.0 1.7 0.086 12.3 1.2 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain Grp1_Fun34_YaaH PF01184.14 CBZ23171.1 - 1.4e-56 191.1 17.3 1.9e-56 190.6 12.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Grp1_Fun34_YaaH PF01184.14 CBZ23173.1 - 8.8e-56 188.5 17.0 1.2e-55 188.0 11.8 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.11 CBZ23174.1 - 7.7e-29 100.4 17.4 1.8e-18 66.4 0.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 CBZ23174.1 - 4.3e-06 25.0 0.1 0.0001 20.5 0.0 2.4 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CoA_binding_3 PF13727.1 CBZ23174.1 - 0.017 14.9 1.9 2 8.2 1.0 2.6 2 0 0 2 2 2 0 CoA-binding domain ResB PF05140.9 CBZ23174.1 - 0.018 13.6 0.0 0.028 12.9 0.0 1.2 1 0 0 1 1 1 0 ResB-like family DUF1228 PF06779.9 CBZ23174.1 - 5.3 7.1 12.1 0.22 11.5 0.5 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) Ribosomal_60s PF00428.14 CBZ23176.1 - 1.5e-19 70.1 10.9 1.7e-19 70.0 7.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1180 PF06679.7 CBZ23176.1 - 0.15 11.9 0.4 0.18 11.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Ribosomal_60s PF00428.14 CBZ23177.1 - 2.2e-19 69.6 10.9 2.6e-19 69.3 7.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TLD PF07534.11 CBZ23178.1 - 7.4e-15 55.1 0.0 1.2e-13 51.2 0.0 2.2 2 0 0 2 2 2 1 TLD Ank_2 PF12796.2 CBZ23181.1 - 2.5e-61 204.0 0.0 3.3e-18 65.8 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ23181.1 - 2.6e-35 118.4 3.5 2e-08 33.6 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CBZ23181.1 - 3.5e-31 107.0 4.4 9.2e-10 38.7 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ23181.1 - 1.5e-30 104.5 4.0 7e-10 38.8 0.0 5.6 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ23181.1 - 3.3e-23 79.4 2.8 0.00026 20.9 0.0 6.9 7 0 0 7 7 7 4 Ankyrin repeat zf-DHHC PF01529.15 CBZ23181.1 - 1.1e-07 31.4 0.1 3.1e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase PHO4 PF01384.15 CBZ23183.1 - 1.7e-90 302.9 14.1 2e-90 302.7 9.8 1.0 1 0 0 1 1 1 1 Phosphate transporter family DSPc PF00782.15 CBZ23184.1 - 0.029 13.9 0.3 0.066 12.7 0.2 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RRM_1 PF00076.17 CBZ23185.1 - 2.3e-11 43.1 0.5 0.00012 21.6 0.0 4.8 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23185.1 - 2.5e-05 24.1 0.2 0.14 12.1 0.0 5.0 6 0 0 6 6 6 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ23185.1 - 0.022 14.5 0.1 25 4.8 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.13 CBZ23186.1 - 0.071 11.7 0.0 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) AAA PF00004.24 CBZ23187.1 - 6.6e-45 152.5 0.0 1.2e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBZ23187.1 - 9.6e-08 32.1 0.0 2.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CBZ23187.1 - 8.4e-07 28.7 0.1 7.3e-06 25.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ23187.1 - 2.2e-06 27.8 0.1 0.0046 17.1 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ23187.1 - 2.2e-06 27.8 0.0 0.00015 21.8 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CBZ23187.1 - 3.3e-06 26.6 0.4 0.00058 19.3 0.1 2.4 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBZ23187.1 - 6.3e-06 25.4 0.0 1.6e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBZ23187.1 - 0.00013 21.6 0.1 0.00027 20.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 CBZ23187.1 - 0.0002 20.3 0.0 0.00044 19.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CBZ23187.1 - 0.0007 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBZ23187.1 - 0.00093 18.0 0.0 0.0018 17.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 CBZ23187.1 - 0.0011 18.3 0.8 0.0021 17.5 0.1 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 CBZ23187.1 - 0.0013 19.5 0.9 0.0025 18.5 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CBZ23187.1 - 0.0014 18.8 0.2 0.006 16.8 0.0 2.1 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CBZ23187.1 - 0.0015 17.7 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CBZ23187.1 - 0.0015 18.6 0.0 0.0044 17.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Parvo_NS1 PF01057.12 CBZ23187.1 - 0.0042 16.0 0.0 0.0072 15.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CBZ23187.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBZ23187.1 - 0.012 15.3 1.1 1 9.0 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase ABC_tran PF00005.22 CBZ23187.1 - 0.015 15.5 0.1 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_3 PF07726.6 CBZ23187.1 - 0.016 14.8 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBZ23187.1 - 0.017 14.6 0.1 0.093 12.2 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 CBZ23187.1 - 0.017 14.3 0.1 0.042 13.0 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 CBZ23187.1 - 0.019 14.0 2.4 0.14 11.2 0.0 2.6 2 1 1 3 3 3 0 KaiC AAA_28 PF13521.1 CBZ23187.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CBZ23187.1 - 0.022 14.4 0.1 0.24 11.0 0.0 2.1 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.7 CBZ23187.1 - 0.028 13.5 0.1 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CBZ23187.1 - 0.031 14.1 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CBZ23187.1 - 0.091 12.3 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 CBZ23187.1 - 0.12 11.8 0.2 0.58 9.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CBZ23187.1 - 0.37 11.0 2.2 3.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain GpcrRhopsn4 PF10192.4 CBZ23188.1 - 0.021 14.0 3.1 0.44 9.6 1.1 2.5 2 0 0 2 2 2 0 Rhodopsin-like GPCR transmembrane domain PIP49_N PF14875.1 CBZ23188.1 - 6.7 6.3 4.2 1.8 8.1 0.0 2.0 2 0 0 2 2 2 0 N-term cysteine-rich ER, FAM69 ADH_zinc_N PF00107.21 CBZ23190.1 - 8.5e-22 77.0 0.1 1.7e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBZ23190.1 - 1.1e-19 71.5 0.0 3.3e-19 70.0 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBZ23190.1 - 1.2e-10 41.0 0.4 2.4e-10 40.1 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 CBZ23190.1 - 0.059 13.3 0.8 0.11 12.4 0.6 1.6 1 1 0 1 1 1 0 NADH(P)-binding Helicase_C_2 PF13307.1 CBZ23192.1 - 4.9e-41 140.4 0.0 8.5e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBZ23192.1 - 2.3e-19 69.4 0.2 1.6e-06 27.6 0.0 4.3 4 0 0 4 4 4 4 DEAD_2 Methyltransf_31 PF13847.1 CBZ23193.1 - 3.7e-09 36.3 0.0 5.5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ23193.1 - 2e-07 31.5 0.0 6.2e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ23193.1 - 0.00014 22.1 0.0 0.00035 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ23193.1 - 0.00071 20.0 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ23193.1 - 0.00081 18.8 0.0 0.0019 17.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBZ23193.1 - 0.0013 18.7 0.4 0.0033 17.4 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 CBZ23193.1 - 0.0029 16.7 0.0 0.0058 15.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 CBZ23193.1 - 0.0044 17.4 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CBZ23193.1 - 0.0057 15.3 0.0 0.009 14.7 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_9 PF08003.6 CBZ23193.1 - 0.006 15.3 0.0 0.011 14.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.14 CBZ23193.1 - 0.081 12.9 0.0 0.24 11.3 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase ArgK PF03308.11 CBZ23194.1 - 2.6e-72 242.8 0.0 3.3e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 CBZ23194.1 - 8.2e-09 35.1 0.0 3.6e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CBZ23194.1 - 0.0012 18.2 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 CBZ23194.1 - 0.0018 18.0 0.1 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain GTP_EFTU PF00009.22 CBZ23194.1 - 0.0033 16.8 0.0 0.18 11.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CBZ23194.1 - 0.0042 17.0 0.1 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.18 CBZ23194.1 - 0.006 16.0 0.0 0.0094 15.3 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SMC_N PF02463.14 CBZ23194.1 - 0.0071 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CBZ23194.1 - 0.022 14.1 0.0 0.033 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 CBZ23194.1 - 0.041 13.3 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 CBZ23194.1 - 0.1 11.8 0.0 1.9 7.6 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_24 PF13479.1 CBZ23194.1 - 0.22 11.0 1.2 5.6 6.4 0.1 2.4 1 1 1 2 2 2 0 AAA domain DUF3285 PF11688.3 CBZ23198.1 - 1.6 8.3 5.6 0.2 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) EmrE PF13536.1 CBZ23199.1 - 1.5e-05 25.1 26.4 2.3e-05 24.5 5.5 3.7 3 1 0 3 3 3 3 Multidrug resistance efflux transporter AAA_16 PF13191.1 CBZ23200.1 - 0.00057 19.9 0.5 0.002 18.1 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CBZ23200.1 - 0.012 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain RecA PF00154.16 CBZ23200.1 - 0.013 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Arch_ATPase PF01637.13 CBZ23200.1 - 0.056 13.1 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 CBZ23200.1 - 0.067 12.9 0.2 0.067 12.9 0.1 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 CBZ23200.1 - 0.077 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain HEM4 PF02602.10 CBZ23201.1 - 6.8e-59 198.9 0.8 7.8e-59 198.7 0.6 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DEAD PF00270.24 CBZ23202.1 - 9.6e-20 70.7 0.0 1.9e-18 66.5 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ23202.1 - 3.5e-06 26.9 0.0 1.2e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBZ23202.1 - 0.00062 19.5 0.3 0.0014 18.4 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Beta_helix PF13229.1 CBZ23203.1 - 0.002 17.9 6.3 7.4 6.2 0.0 5.8 5 2 0 5 5 5 2 Right handed beta helix region NosD PF05048.8 CBZ23203.1 - 3.5 6.7 0.1 28 3.7 0.0 2.5 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) tRNA_edit PF04073.10 CBZ23204.1 - 4e-20 71.8 0.1 2.4e-19 69.3 0.1 1.9 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Mqo PF06039.10 CBZ23206.1 - 0.21 9.7 0.0 0.31 9.1 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) COX17 PF05051.8 CBZ23207.1 - 1.7e-19 69.5 7.1 2.1e-19 69.2 4.9 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) TatD_DNase PF01026.16 CBZ23208.1 - 1.5e-57 194.7 0.0 2.3e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase DUF3783 PF12646.2 CBZ23208.1 - 0.08 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Fmp27_WPPW PF10359.4 CBZ23208.1 - 2.4 6.4 8.7 3.6 5.8 6.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF572 PF04502.8 CBZ23208.1 - 3.1 6.9 21.4 5.2 6.1 14.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) LRR_4 PF12799.2 CBZ23210.1 - 1.2e-12 47.0 9.4 0.00017 21.1 0.4 4.2 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.1 CBZ23210.1 - 4.3e-09 36.4 0.0 8.3e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_8 PF13855.1 CBZ23210.1 - 2.1e-07 30.5 6.5 0.0062 16.2 1.5 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 CBZ23210.1 - 3.9e-06 26.3 0.9 2 8.7 0.0 5.6 5 0 0 5 5 5 1 Leucine Rich repeat ubiquitin PF00240.18 CBZ23210.1 - 8.9e-06 25.0 0.2 0.0002 20.6 0.2 2.4 1 1 0 1 1 1 1 Ubiquitin family LRR_9 PF14580.1 CBZ23210.1 - 2.2e-05 24.1 0.5 0.39 10.2 0.0 3.6 3 1 0 3 3 3 2 Leucine-rich repeat LRR_7 PF13504.1 CBZ23210.1 - 0.00026 20.6 15.5 0.93 9.9 0.1 6.3 6 0 0 6 6 6 1 Leucine rich repeat LRR_1 PF00560.28 CBZ23210.1 - 0.0012 18.6 9.8 8.2 6.8 0.0 5.9 7 0 0 7 7 7 2 Leucine Rich Repeat Pkinase PF00069.20 CBZ23211.1 - 3.9e-54 183.5 0.0 6.7e-32 110.6 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23211.1 - 8.8e-23 80.6 0.1 6.3e-11 41.8 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23211.1 - 0.0046 15.9 0.0 0.0087 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CBZ23211.1 - 4.8 5.8 0.0 7.2 5.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNA_pol_Rpb4 PF03874.11 CBZ23212.1 - 0.043 13.8 0.0 0.72 9.8 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb4 6PF2K PF01591.13 CBZ23213.1 - 1.3e-64 217.3 0.0 1.9e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank_2 PF12796.2 CBZ23213.1 - 1.2e-14 54.4 0.2 2.9e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ23213.1 - 9.4e-14 50.4 0.3 7.5e-09 34.9 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CBZ23213.1 - 6.5e-13 48.4 1.8 8.4e-10 38.5 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBZ23213.1 - 7.2e-13 48.6 1.4 2e-09 37.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ23213.1 - 1.1e-08 34.4 0.1 0.00099 19.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat AAA_33 PF13671.1 CBZ23213.1 - 1e-06 28.6 0.4 3e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBZ23213.1 - 0.0042 17.8 0.0 0.008 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain USP7_C2 PF14533.1 CBZ23213.1 - 1.5 8.2 0.0 2.6 7.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Apc5 PF12862.2 CBZ23215.1 - 0.28 11.0 4.7 1.3 8.9 3.2 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 YebO PF13974.1 CBZ23215.1 - 1.7 8.4 5.5 13 5.6 3.8 2.4 2 0 0 2 2 2 0 YebO-like protein DUF3800 PF12686.2 CBZ23215.1 - 9 5.8 0.1 15 5.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) CDP-OH_P_transf PF01066.16 CBZ23216.1 - 1.3e-19 70.3 0.3 1.3e-19 70.3 0.2 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase zf-MYND PF01753.13 CBZ23218.1 - 0.047 13.5 6.5 0.099 12.5 4.5 1.6 1 0 0 1 1 1 0 MYND finger LRR_4 PF12799.2 CBZ23221.1 - 3.6e-12 45.6 5.6 0.00085 18.8 0.1 5.1 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ23221.1 - 1.1e-06 28.3 14.6 0.00044 19.9 0.4 3.5 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CBZ23221.1 - 0.00054 19.6 11.7 7.3 7.0 0.2 6.7 6 1 1 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.1 CBZ23221.1 - 0.00069 19.4 7.4 13 6.2 0.0 6.4 6 1 1 7 7 7 1 Leucine Rich repeat NIF PF03031.13 CBZ23223.1 - 1.4e-27 96.3 0.0 8.2e-20 71.0 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Brix PF04427.13 CBZ23224.1 - 9.2e-44 149.3 0.1 1.4e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 Brix domain Pyrophosphatase PF00719.14 CBZ23225.1 - 9.1e-45 151.8 0.0 1.1e-44 151.5 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Got1 PF04178.7 CBZ23226.1 - 5.3e-29 100.7 20.1 7.6e-29 100.2 13.9 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Polysacc_synt_3 PF13440.1 CBZ23226.1 - 0.41 10.0 17.0 0.28 10.6 8.6 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein DUF3816 PF12822.2 CBZ23226.1 - 1.6 8.6 17.8 0.12 12.2 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) Peptidase_U4 PF03419.8 CBZ23226.1 - 3 6.8 11.6 3.6 6.5 7.8 1.3 1 1 0 1 1 1 0 Sporulation factor SpoIIGA SdpI PF13630.1 CBZ23226.1 - 5.1 6.8 12.4 4.5 7.0 1.3 2.5 2 0 0 2 2 2 0 SdpI/YhfL protein family PalH PF08733.5 CBZ23226.1 - 5.6 5.7 11.0 20 3.8 7.6 1.9 1 1 0 1 1 1 0 PalH/RIM21 Amidohydro_3 PF07969.6 CBZ23227.1 - 1e-51 176.4 0.7 8.5e-26 91.0 3.0 2.2 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 CBZ23227.1 - 7.1e-11 42.3 2.9 3.4e-06 26.9 0.0 3.1 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 CBZ23227.1 - 1.6e-08 34.2 0.2 1.3e-07 31.2 0.1 2.6 2 1 0 2 2 2 1 Amidohydrolase CENP-W PF15510.1 CBZ23228.1 - 0.045 13.7 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Centromere kinetochore component W Cu-oxidase_2 PF07731.9 CBZ23229.1 - 6.3e-17 61.3 3.5 6.3e-17 61.3 2.4 3.6 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 CBZ23229.1 - 2.5e-09 36.8 6.2 2e-06 27.5 0.6 3.8 3 1 1 4 4 4 2 Multicopper oxidase MORN PF02493.15 CBZ23231.1 - 9.2e-24 81.7 37.6 1.5e-06 27.5 0.9 7.2 7 1 0 7 7 7 6 MORN repeat EIF_2_alpha PF07541.7 CBZ23232.1 - 3.4e-24 84.7 0.0 2.1e-22 78.9 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CBZ23232.1 - 3e-11 43.2 0.4 6.1e-11 42.2 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 CBZ23232.1 - 0.0035 17.2 0.4 0.0076 16.1 0.3 1.6 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 E1-E2_ATPase PF00122.15 CBZ23233.1 - 6.5e-66 221.6 2.0 6.5e-66 221.6 1.4 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBZ23233.1 - 2.7e-43 147.5 6.1 2.7e-43 147.5 4.2 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBZ23233.1 - 4.8e-31 108.8 0.0 5.1e-30 105.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ23233.1 - 8e-18 64.1 0.0 2e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBZ23233.1 - 1e-15 56.9 0.0 4e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBZ23233.1 - 2.5e-13 50.6 0.1 9.7e-13 48.7 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBZ23233.1 - 3.4e-07 30.1 1.3 8.9e-06 25.4 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBZ23233.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase BT1 PF03092.11 CBZ23234.1 - 2.1e-141 471.5 12.7 2.6e-141 471.2 8.8 1.0 1 0 0 1 1 1 1 BT1 family PDEase_I PF00233.14 CBZ23235.1 - 1.4e-10 41.3 0.2 2.2e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Phosphoprotein PF00922.12 CBZ23235.1 - 0.0089 15.2 1.8 0.023 13.9 1.2 1.7 1 0 0 1 1 1 1 Vesiculovirus phosphoprotein Topo_C_assoc PF14370.1 CBZ23240.1 - 1.1e-28 98.7 0.4 1.5e-28 98.2 0.2 1.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain BUD22 PF09073.5 CBZ23240.1 - 0.03 13.4 1.6 0.033 13.2 1.1 1.1 1 0 0 1 1 1 0 BUD22 RAP1 PF07218.6 CBZ23240.1 - 0.086 10.9 12.2 0.11 10.5 8.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AF-4 PF05110.8 CBZ23240.1 - 0.44 8.3 23.5 0.56 8.0 16.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF2217 PF10265.4 CBZ23240.1 - 0.63 8.7 5.2 0.79 8.4 3.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 CBZ23240.1 - 1 7.5 5.2 1.3 7.2 3.6 1.1 1 0 0 1 1 1 0 Transmembrane protein CAF-1_p150 PF11600.3 CBZ23240.1 - 1.9 7.8 5.5 2.7 7.3 3.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Secretin_N_2 PF07655.8 CBZ23240.1 - 6.1 7.3 17.1 12 6.4 11.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Golgin_A5 PF09787.4 CBZ23240.1 - 8.4 4.7 8.6 11 4.3 6.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Methyltransf_31 PF13847.1 CBZ23241.1 - 0.00025 20.6 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ23241.1 - 0.0024 18.4 0.1 0.0048 17.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ23241.1 - 0.0075 16.6 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Takusan PF04822.8 CBZ23242.1 - 0.024 14.3 0.8 0.043 13.5 0.5 1.4 1 0 0 1 1 1 0 Takusan Hemerythrin PF01814.18 CBZ23242.1 - 0.025 14.7 1.8 0.038 14.1 1.2 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Apt1 PF10351.4 CBZ23242.1 - 0.044 12.6 0.0 0.048 12.5 0.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CorA PF01544.13 CBZ23242.1 - 0.056 12.4 0.3 0.069 12.1 0.2 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DASH_Dam1 PF08653.5 CBZ23242.1 - 0.12 12.1 0.2 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 WXG100 PF06013.7 CBZ23242.1 - 0.14 12.2 0.2 0.14 12.2 0.2 1.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Osmo_CC PF08946.5 CBZ23242.1 - 0.21 11.6 0.8 0.38 10.8 0.6 1.4 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF3584 PF12128.3 CBZ23244.1 - 0.012 12.9 5.9 0.018 12.4 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) eIF3_N PF09440.5 CBZ23244.1 - 0.16 12.1 2.4 0.41 10.8 0.1 2.1 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain BRE1 PF08647.6 CBZ23244.1 - 1.1 9.3 4.5 15 5.6 0.6 3.0 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase TMF_TATA_bd PF12325.3 CBZ23244.1 - 8.6 6.1 8.3 0.81 9.4 1.0 2.4 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Mnd1 PF03962.10 CBZ23245.1 - 3.4 7.2 7.5 1.2 8.8 2.5 2.1 3 0 0 3 3 3 0 Mnd1 family YlbE PF14003.1 CBZ23248.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 YlbE-like protein HALZ PF02183.13 CBZ23248.1 - 0.16 11.7 0.7 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper VSP PF03302.8 CBZ23250.1 - 1.1e-06 27.5 151.0 0.00066 18.4 7.9 7.6 1 1 6 8 8 8 6 Giardia variant-specific surface protein VSP PF03302.8 CBZ23251.1 - 0.00014 20.6 121.8 0.0029 16.3 9.2 7.5 2 1 6 8 8 8 6 Giardia variant-specific surface protein VSP PF03302.8 CBZ23252.1 - 0.16 10.6 23.1 0.053 12.1 12.6 2.2 2 1 0 2 2 2 0 Giardia variant-specific surface protein GBP_PSP PF02425.10 CBZ23252.1 - 0.52 9.8 6.8 0.29 10.7 0.8 2.8 2 1 0 2 2 2 0 Paralytic/GBP/PSP peptide cEGF PF12662.2 CBZ23252.1 - 0.8 9.4 9.2 2.5 7.7 0.4 2.8 2 0 0 2 2 2 0 Complement Clr-like EGF-like VSP PF03302.8 CBZ23253.1 - 0.023 13.3 41.5 0.019 13.5 4.2 3.9 1 1 2 4 4 4 0 Giardia variant-specific surface protein Med3 PF11593.3 CBZ23253.1 - 3.3 6.8 23.0 4.4 6.4 16.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Shisa PF13908.1 CBZ23255.1 - 0.00038 20.7 1.3 0.00038 20.7 0.9 1.8 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator RP-C_C PF11800.3 CBZ23255.1 - 0.01 15.5 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Orthoreo_P10 PF07204.6 CBZ23255.1 - 0.023 14.4 0.1 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 TMEM52 PF14979.1 CBZ23255.1 - 0.19 11.6 1.0 0.35 10.7 0.7 1.5 1 1 0 1 1 1 0 Transmembrane 52 Sporozoite_P67 PF05642.6 CBZ23255.1 - 0.97 7.2 3.9 1.6 6.5 2.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen GRAM PF02893.15 CBZ23256.1 - 2.9e-05 23.4 0.0 6.3e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 GRAM domain PseudoU_synth_2 PF00849.17 CBZ23257.1 - 2.1e-41 141.4 0.0 3.6e-41 140.7 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TPR_11 PF13414.1 CBZ23258.1 - 5.7e-07 29.0 13.0 0.0068 16.0 0.1 3.8 2 1 0 4 4 4 3 TPR repeat TPR_10 PF13374.1 CBZ23258.1 - 0.00021 21.1 3.0 0.00024 20.9 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ23258.1 - 0.00031 20.4 13.2 0.003 17.3 0.0 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ23258.1 - 0.00036 20.0 10.5 0.0022 17.5 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ23258.1 - 0.0034 17.2 0.2 0.0034 17.2 0.1 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ23258.1 - 0.01 15.6 0.1 0.03 14.2 0.1 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat ATG16 PF08614.6 CBZ23258.1 - 0.14 11.9 1.3 1 9.1 0.3 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) TPR_7 PF13176.1 CBZ23258.1 - 0.16 11.8 5.3 0.22 11.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MRP-L47 PF06984.8 CBZ23259.1 - 4.1e-29 100.3 0.2 7.8e-29 99.4 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) A_deaminase PF00962.17 CBZ23260.1 - 4e-80 269.2 0.4 1.5e-55 188.4 0.0 3.2 3 0 0 3 3 3 2 Adenosine/AMP deaminase Syntaxin PF00804.20 CBZ23260.1 - 0.12 12.5 3.8 2.4 8.3 1.8 2.4 2 0 0 2 2 2 0 Syntaxin DUF2730 PF10805.3 CBZ23260.1 - 0.17 11.6 0.5 0.36 10.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) ERM PF00769.14 CBZ23260.1 - 0.86 9.0 8.2 1.6 8.1 5.7 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ADH_N PF08240.7 CBZ23261.1 - 7e-07 28.9 0.5 1.4e-06 28.0 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBZ23261.1 - 0.00017 21.1 0.0 0.00032 20.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4164 PF13747.1 CBZ23262.1 - 0.0044 17.1 0.1 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) TRCF PF03461.10 CBZ23262.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 TRCF domain Glyco_hydro_32N PF00251.15 CBZ23263.1 - 5.5e-60 203.3 8.6 7.3e-60 202.9 5.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CBZ23263.1 - 5.1e-05 23.5 0.0 0.014 15.7 0.0 2.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal PAN_1 PF00024.21 CBZ23263.1 - 5.7e-05 22.7 0.4 0.00012 21.7 0.3 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 CBZ23263.1 - 0.012 15.2 1.5 0.037 13.7 1.1 1.8 1 0 0 1 1 1 0 PAN domain Glyco_hydro_32N PF00251.15 CBZ23264.1 - 1.4e-18 67.3 0.1 2e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CBZ23264.1 - 7.1e-06 26.3 0.0 0.0044 17.3 0.0 3.0 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 C terminal PAN_1 PF00024.21 CBZ23264.1 - 2.9e-05 23.7 0.4 6.1e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 CBZ23264.1 - 0.0072 16.0 1.5 0.021 14.5 1.1 1.8 1 0 0 1 1 1 1 PAN domain RNB PF00773.14 CBZ23265.1 - 4.2e-57 193.8 0.0 9.7e-57 192.6 0.0 1.5 2 0 0 2 2 2 1 RNB domain Arf PF00025.16 CBZ23266.1 - 5.5e-54 182.0 0.0 6.5e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CBZ23266.1 - 5.2e-15 55.1 0.0 6e-15 54.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ23266.1 - 9.7e-12 45.4 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CBZ23266.1 - 1.3e-10 40.8 0.0 1.6e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBZ23266.1 - 3.2e-09 36.2 0.0 3.8e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CBZ23266.1 - 8e-08 31.3 0.2 1.7e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CBZ23266.1 - 4.4e-06 26.6 0.0 6.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 CBZ23266.1 - 0.071 12.7 0.1 0.1 12.2 0.0 1.4 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 CBZ23266.1 - 0.13 12.2 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain Ecl1 PF12855.2 CBZ23267.1 - 5.7 6.3 6.0 14 5.0 4.2 1.6 1 0 0 1 1 1 0 Life-span regulatory factor LTXXQ PF07813.7 CBZ23268.1 - 0.19 12.1 6.8 0.14 12.6 3.4 1.8 2 0 0 2 2 2 0 LTXXQ motif family protein PhyH PF05721.8 CBZ23269.1 - 6.5e-43 147.2 0.0 8.7e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3243 PF11588.3 CBZ23269.1 - 0.016 15.1 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) Shisa PF13908.1 CBZ23270.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator CcoS PF03597.10 CBZ23270.1 - 0.0021 17.4 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase maturation protein cbb3-type DUF3481 PF11980.3 CBZ23270.1 - 0.0064 16.2 0.4 0.024 14.4 0.0 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3481) Epiglycanin_C PF14654.1 CBZ23270.1 - 0.017 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region m04gp34like PF12216.3 CBZ23270.1 - 0.025 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Immune evasion protein EphA2_TM PF14575.1 CBZ23270.1 - 0.07 13.5 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain L6_membrane PF05805.7 CBZ23270.1 - 0.21 11.1 1.9 0.79 9.2 0.1 2.1 2 0 0 2 2 2 0 L6 membrane protein APC10 PF03256.11 CBZ23271.1 - 5e-73 244.8 0.0 4e-66 222.3 0.0 2.0 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) TPR_1 PF00515.23 CBZ23273.1 - 1.5e-08 33.8 3.9 0.00094 18.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ23273.1 - 3.4e-08 32.9 7.2 0.0018 17.8 0.1 3.8 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 CBZ23273.1 - 1.1e-06 28.0 13.1 8.3e-05 22.2 0.2 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ23273.1 - 3.8e-06 26.2 0.2 0.0028 17.3 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ23273.1 - 1.8e-05 24.9 2.9 0.003 18.0 0.0 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat SNAP PF14938.1 CBZ23273.1 - 0.0034 16.5 1.0 0.049 12.7 0.3 2.3 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.1 CBZ23273.1 - 0.0049 16.5 4.5 0.27 11.1 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ23273.1 - 0.016 15.0 6.4 0.97 9.3 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ23273.1 - 0.017 15.5 0.1 3 8.4 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ23273.1 - 0.031 14.1 13.6 0.61 10.0 0.1 4.7 2 1 3 5 5 5 0 Tetratricopeptide repeat Spore_SspJ PF09575.5 CBZ23273.1 - 0.097 12.8 1.3 0.35 11.1 0.9 1.9 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) TipAS PF07739.8 CBZ23273.1 - 0.16 12.2 1.6 0.35 11.1 0.1 2.4 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain TPR_19 PF14559.1 CBZ23273.1 - 0.3 11.4 0.1 0.3 11.4 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ23273.1 - 2.8 8.7 23.5 1.3 9.8 0.9 5.1 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 CBZ23273.1 - 3 7.7 17.7 0.55 10.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat EMP24_GP25L PF01105.19 CBZ23274.1 - 4.1 7.0 0.0 71 3.0 0.0 2.7 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 CBZ23275.1 - 3.9e-43 147.4 0.0 1.5e-35 122.5 0.0 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23275.1 - 9.6e-33 113.3 0.0 8.2e-16 57.8 0.0 4.2 4 0 0 4 4 4 4 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBZ23275.1 - 1.2 7.8 0.0 1.8 7.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_C2 PF00648.16 CBZ23276.1 - 1.6e-47 161.9 0.0 2.4e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ23276.1 - 1.7e-34 117.9 0.1 4.4e-34 116.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Lyase_1 PF00206.15 CBZ23277.1 - 1.8e-48 165.3 0.0 2.5e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.6 CBZ23277.1 - 8.6e-45 151.2 0.0 1.5e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal N_Asn_amidohyd PF14736.1 CBZ23278.1 - 0.00084 18.2 0.0 0.19 10.5 0.0 3.0 4 0 0 4 4 4 2 Protein N-terminal asparagine amidohydrolase Fes1 PF08609.5 CBZ23278.1 - 0.23 11.9 0.0 0.67 10.4 0.0 1.8 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 Ribosomal_L5_C PF00673.16 CBZ23279.1 - 2.5e-22 78.4 0.0 4.1e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CBZ23279.1 - 9.2e-17 60.5 0.4 3.2e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 Arf PF00025.16 CBZ23280.1 - 5.3e-58 195.1 0.0 6e-58 194.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBZ23280.1 - 6.9e-13 48.2 0.0 8e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBZ23280.1 - 1e-10 41.2 0.0 1.2e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBZ23280.1 - 6.5e-10 38.2 0.0 1.8e-09 36.8 0.0 1.6 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 CBZ23280.1 - 5.7e-07 30.0 0.0 7.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CBZ23280.1 - 9.8e-07 28.1 0.0 1.1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ23280.1 - 0.00044 20.1 0.0 0.00059 19.7 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 CBZ23280.1 - 0.0035 17.0 0.2 0.034 13.8 0.1 2.0 1 1 0 1 1 1 1 NACHT domain GTP_EFTU PF00009.22 CBZ23280.1 - 0.0043 16.5 0.0 0.024 14.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 CBZ23280.1 - 0.014 14.9 0.0 0.053 13.0 0.0 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Macoilin PF09726.4 CBZ23281.1 - 2.5 6.2 6.2 3.2 5.9 4.3 1.2 1 0 0 1 1 1 0 Transmembrane protein NTP_transf_2 PF01909.18 CBZ23282.1 - 1.9e-06 28.0 0.0 3.6e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CBZ23282.1 - 0.0001 22.1 0.1 0.0002 21.2 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF2852 PF11014.3 CBZ23282.1 - 0.36 10.8 4.5 0.13 12.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) Ank_2 PF12796.2 CBZ23284.1 - 6.6e-28 96.8 1.1 4.4e-15 55.7 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ23284.1 - 5.4e-23 80.9 3.3 3.4e-10 40.1 0.0 5.9 4 2 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 CBZ23284.1 - 9.8e-23 78.7 15.7 3.2e-11 42.4 0.0 6.0 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 CBZ23284.1 - 9.1e-20 70.2 8.1 3.3e-12 46.2 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ23284.1 - 5e-18 63.4 3.4 1.2e-06 28.1 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat zf-DHHC PF01529.15 CBZ23284.1 - 5.1e-14 52.0 0.1 5.1e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase OmpH PF03938.9 CBZ23285.1 - 0.035 14.0 1.1 0.081 12.8 0.8 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) EF-hand_6 PF13405.1 CBZ23286.1 - 2.5e-08 33.1 0.0 0.97 9.4 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain zf-RING_2 PF13639.1 CBZ23286.1 - 2.5e-06 27.2 7.7 8e-06 25.5 5.3 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ23286.1 - 3.5e-06 26.9 7.2 3.5e-06 26.9 5.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) EF-hand_7 PF13499.1 CBZ23286.1 - 4.8e-06 26.6 1.2 0.014 15.5 0.5 2.7 1 1 1 2 2 2 2 EF-hand domain pair zf-RING_5 PF14634.1 CBZ23286.1 - 8.7e-06 25.3 5.2 2.7e-05 23.7 3.6 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBZ23286.1 - 1.9e-05 24.1 6.2 7.5e-05 22.3 4.3 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ23286.1 - 2.8e-05 23.8 7.9 2.8e-05 23.8 5.5 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CBZ23286.1 - 0.00052 19.6 4.8 0.00052 19.6 3.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) EF-hand_1 PF00036.27 CBZ23286.1 - 0.00057 18.9 0.0 1.1 8.7 0.0 3.6 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 CBZ23286.1 - 0.0059 16.1 0.1 0.15 11.7 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair WBP-1 PF11669.3 CBZ23286.1 - 0.011 15.8 0.2 0.044 13.8 0.1 2.0 1 0 0 1 1 1 0 WW domain-binding protein 1 zf-RING_6 PF14835.1 CBZ23286.1 - 0.058 13.1 2.4 0.2 11.4 1.6 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBZ23286.1 - 0.13 11.9 4.6 0.082 12.6 1.1 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Rad50_zn_hook PF04423.9 CBZ23286.1 - 0.13 11.7 1.7 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif TPR_19 PF14559.1 CBZ23287.1 - 2.2e-37 127.2 58.4 1.6e-05 25.1 0.2 15.0 8 5 8 16 16 16 10 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ23287.1 - 2e-30 104.7 87.3 1.9e-06 28.3 5.4 16.2 12 4 6 19 19 19 10 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ23287.1 - 6.6e-29 99.3 50.2 1.6e-06 27.6 1.7 13.9 10 5 8 18 18 17 11 TPR repeat TPR_2 PF07719.12 CBZ23287.1 - 4.2e-28 94.9 51.8 0.0034 17.1 0.1 20.4 22 0 0 22 22 22 5 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ23287.1 - 4.9e-24 82.6 94.2 9e-05 22.7 0.7 22.3 11 7 13 24 24 23 7 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ23287.1 - 8.3e-21 72.6 28.4 0.0011 18.5 0.2 13.7 15 0 0 15 15 13 4 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ23287.1 - 1.5e-18 66.4 66.7 0.00065 19.5 0.1 16.9 14 6 5 19 19 19 6 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ23287.1 - 1.6e-14 52.7 17.2 3.4 8.1 0.1 13.7 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ23287.1 - 1.7e-13 49.2 14.0 0.24 11.2 0.1 11.4 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ23287.1 - 1.7e-12 46.1 36.0 0.16 11.8 0.0 13.8 16 0 0 16 16 14 5 Tetratricopeptide repeat Apc3 PF12895.2 CBZ23287.1 - 1e-10 41.6 42.7 0.05 13.7 0.6 10.8 9 3 3 12 12 11 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBZ23287.1 - 4e-07 30.0 67.3 0.048 14.1 0.1 19.1 23 0 0 23 23 20 2 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ23287.1 - 2.8e-06 27.2 47.2 0.04 14.3 0.2 13.4 14 0 0 14 14 11 2 Tetratricopeptide repeat ChAPs PF09295.5 CBZ23287.1 - 0.0062 15.3 0.2 0.16 10.6 0.0 2.7 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.13 CBZ23287.1 - 0.0069 16.2 13.6 5.2 7.0 0.2 6.3 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain NARP1 PF12569.3 CBZ23287.1 - 0.016 14.0 9.3 0.42 9.3 0.0 4.8 6 2 1 7 7 7 0 NMDA receptor-regulated protein 1 PPR PF01535.15 CBZ23287.1 - 0.18 11.8 4.7 8.6 6.5 0.0 5.7 6 0 0 6 6 5 0 PPR repeat Y_phosphatase2 PF03162.8 CBZ23288.1 - 4.2e-51 172.5 0.0 5.5e-51 172.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CBZ23288.1 - 2.8e-08 34.1 0.0 6.6e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CBZ23288.1 - 0.0069 15.7 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBZ23288.1 - 0.051 13.1 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DENN PF02141.16 CBZ23289.1 - 1.9e-10 40.7 0.9 7.1e-10 38.8 0.6 1.9 1 0 0 1 1 1 1 DENN (AEX-3) domain Pox_P4A PF03395.9 CBZ23289.1 - 0.59 7.6 0.0 0.85 7.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4A protein Spermine_synth PF01564.12 CBZ23290.1 - 2.8e-66 222.9 0.0 3.5e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 CBZ23290.1 - 0.0021 18.1 0.0 0.005 16.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ23290.1 - 0.15 12.5 0.1 0.75 10.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain MMgT PF10270.4 CBZ23291.1 - 0.016 15.6 0.0 0.075 13.4 0.0 2.0 2 0 0 2 2 2 0 Membrane magnesium transporter Vma12 PF11712.3 CBZ23291.1 - 0.14 11.8 0.5 0.31 10.7 0.4 1.7 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Glyco_trans_1_2 PF13524.1 CBZ23291.1 - 0.99 9.7 3.2 0.97 9.7 0.6 2.1 2 1 0 2 2 2 0 Glycosyl transferases group 1 Ank_2 PF12796.2 CBZ23292.1 - 2e-18 66.5 2.2 2.4e-05 24.5 0.0 5.1 6 0 0 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ23292.1 - 2.2e-13 50.2 2.5 0.018 15.5 0.0 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 CBZ23292.1 - 9.3e-13 47.2 11.6 0.00058 19.5 0.1 6.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 CBZ23292.1 - 1e-12 47.8 16.1 0.0012 18.9 0.1 6.6 7 0 0 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ23292.1 - 1e-07 31.4 3.6 0.062 13.5 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat MRAP PF15183.1 CBZ23292.1 - 1.2 8.8 0.4 2.9 7.5 0.3 1.6 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF1168 PF06658.7 CBZ23293.1 - 0.0084 15.6 14.5 0.011 15.2 10.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Cwf_Cwc_15 PF04889.7 CBZ23293.1 - 0.014 15.0 12.9 0.016 14.9 8.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cu-oxidase_4 PF02578.10 CBZ23293.1 - 0.049 12.7 0.4 0.061 12.3 0.3 1.1 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase Vir_act_alpha_C PF10400.4 CBZ23293.1 - 0.14 12.5 7.5 0.32 11.3 4.7 2.0 1 1 1 2 2 2 0 Virulence activator alpha C-term DUF4603 PF15376.1 CBZ23293.1 - 0.34 8.0 11.5 0.42 7.7 7.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) RNA_pol_3_Rpc31 PF11705.3 CBZ23293.1 - 0.87 9.4 6.8 1.3 8.9 4.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 ECM11 PF15463.1 CBZ23294.1 - 0.05 13.8 0.2 0.05 13.8 0.1 2.6 3 0 0 3 3 3 0 Extracellular mutant protein 11 PolyA_pol_RNAbd PF12627.2 CBZ23295.1 - 0.077 12.5 0.2 0.21 11.1 0.1 1.7 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Y1_Tnp PF01797.11 CBZ23296.1 - 0.015 15.1 0.2 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Transposase IS200 like HCNGP PF07818.8 CBZ23296.1 - 0.016 15.2 0.1 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 HCNGP-like protein TFIID-18kDa PF02269.11 CBZ23296.1 - 0.033 14.0 0.4 0.067 13.0 0.3 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF600 PF04634.7 CBZ23296.1 - 0.033 14.2 1.5 0.092 12.7 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF600 DUF334 PF03904.8 CBZ23296.1 - 0.085 12.1 3.6 0.56 9.4 2.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF334) zf-C3HC4_3 PF13920.1 CBZ23297.1 - 5.9e-09 35.4 8.8 1.1e-08 34.6 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ23297.1 - 1e-06 28.2 9.7 1.9e-06 27.4 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ23297.1 - 5.8e-06 26.2 12.2 1e-05 25.4 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ23297.1 - 6.2e-05 22.7 13.1 0.00012 21.7 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBZ23297.1 - 0.0015 18.2 10.2 0.0034 17.0 7.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain TMEM154 PF15102.1 CBZ23297.1 - 0.0093 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family DAP10 PF07213.6 CBZ23297.1 - 0.03 14.0 0.6 0.22 11.3 0.1 2.4 2 0 0 2 2 2 0 DAP10 membrane protein zf-C3HC4_4 PF15227.1 CBZ23297.1 - 0.12 12.2 10.3 0.31 10.9 7.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 CBZ23297.1 - 0.56 9.9 4.1 1.1 8.9 2.8 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 CBZ23297.1 - 1.5 8.4 8.3 3.2 7.4 5.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.20 CBZ23298.1 - 6.8e-39 133.5 0.9 4.3e-13 49.0 0.0 5.7 5 2 0 5 5 5 4 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23298.1 - 1.2e-12 47.5 0.0 3.6e-08 32.7 0.0 3.9 4 0 0 4 4 4 2 Protein tyrosine kinase FHA PF00498.21 CBZ23298.1 - 1.3e-11 44.4 0.2 3.2e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 FHA domain TGS PF02824.16 CBZ23298.1 - 0.061 13.1 0.2 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 TGS domain DUF2076 PF09849.4 CBZ23299.1 - 1.9e-06 28.1 3.1 2.2e-06 27.9 2.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CBZ23299.1 - 5.2e-05 23.0 1.9 7e-05 22.6 1.3 1.2 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 CBZ23300.1 - 1.6e-06 28.3 3.7 1.8e-06 28.2 2.6 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CBZ23300.1 - 5.3e-05 23.0 1.9 7.4e-05 22.5 1.3 1.2 1 0 0 1 1 1 1 CHCH domain UQ_con PF00179.21 CBZ23301.1 - 7.1e-46 155.1 0.1 8e-46 154.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ23301.1 - 0.00043 20.0 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CBZ23301.1 - 0.0049 16.5 0.2 0.011 15.3 0.1 1.6 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 CBZ23301.1 - 0.045 13.6 0.6 0.055 13.3 0.4 1.5 1 1 0 1 1 1 0 RWD domain Ax_dynein_light PF10211.4 CBZ23302.1 - 4.5e-10 39.6 7.6 8.4e-09 35.5 3.0 2.6 2 0 0 2 2 2 2 Axonemal dynein light chain CesT PF05932.8 CBZ23304.1 - 1.1e-09 38.1 0.1 2.9e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family PDZ_2 PF13180.1 CBZ23304.1 - 1.2e-08 34.7 0.0 4.5e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 PDZ domain DUF974 PF06159.8 CBZ23306.1 - 1.5e-07 31.1 0.0 2.7e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF974) WASH_WAHD PF11945.3 CBZ23307.1 - 0.0003 20.1 0.0 0.00046 19.5 0.0 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex Spt5_N PF11942.3 CBZ23307.1 - 0.067 13.8 6.2 0.21 12.2 4.3 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Ribosomal_L16 PF00252.13 CBZ23308.1 - 3.4e-27 94.8 0.3 4.3e-27 94.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e NAC PF01849.13 CBZ23309.1 - 2.6e-18 65.3 0.4 5.7e-18 64.1 0.0 1.7 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CBZ23309.1 - 0.0064 16.3 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain NCD2 PF04905.8 CBZ23309.1 - 0.056 13.2 0.2 0.056 13.2 0.1 1.9 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) NAC PF01849.13 CBZ23310.1 - 8.4e-19 66.8 0.6 2.3e-18 65.4 0.0 1.9 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CBZ23310.1 - 0.0028 17.4 0.1 0.0057 16.4 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF2722 PF10846.3 CBZ23310.1 - 0.1 11.5 1.6 0.12 11.3 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NCD2 PF04905.8 CBZ23310.1 - 0.38 10.5 4.0 0.31 10.8 0.2 2.0 2 0 0 2 2 2 0 NAB conserved region 2 (NCD2) Myc_N PF01056.13 CBZ23310.1 - 1.1 8.3 4.3 1.4 7.9 3.0 1.5 1 1 0 1 1 1 0 Myc amino-terminal region Tmemb_185A PF10269.4 CBZ23311.1 - 0.21 11.1 15.8 1.7 8.1 4.6 3.0 3 1 0 3 3 3 0 Transmembrane Fragile-X-F protein Pex14_N PF04695.8 CBZ23311.1 - 7.5 6.6 6.6 60 3.6 0.1 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pescadillo_N PF06732.6 CBZ23314.1 - 5e-111 370.4 5.5 1.1e-110 369.3 3.8 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.21 CBZ23314.1 - 2.5e-07 30.7 0.0 1e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Pep_deformylase PF01327.16 CBZ23315.1 - 4.5e-26 91.1 0.0 6.9e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Polypeptide deformylase DUF1523 PF07509.6 CBZ23315.1 - 0.092 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) Med1 PF10744.4 CBZ23315.1 - 0.2 10.4 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Y_phosphatase2 PF03162.8 CBZ23317.1 - 1.8e-55 186.8 0.0 2.4e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CBZ23317.1 - 0.0022 18.2 0.0 0.0039 17.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Rhomboid PF01694.17 CBZ23318.1 - 7.2e-06 26.0 4.2 7.2e-06 26.0 2.9 2.1 2 1 0 2 2 2 1 Rhomboid family Ribosomal_L30 PF00327.15 CBZ23319.1 - 0.00034 20.1 0.1 0.0013 18.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e TPR_12 PF13424.1 CBZ23321.1 - 1.3e-05 25.0 2.7 0.061 13.2 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ23321.1 - 0.0037 16.9 0.6 0.0086 15.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ23321.1 - 0.018 14.9 0.5 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ23321.1 - 0.018 14.6 0.1 0.061 12.9 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat IQ PF00612.22 CBZ23321.1 - 0.029 14.0 0.1 0.076 12.7 0.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif TPR_11 PF13414.1 CBZ23321.1 - 0.044 13.4 1.0 0.058 13.0 0.0 1.7 2 0 0 2 2 2 0 TPR repeat CaMBD PF02888.11 CBZ23321.1 - 0.13 12.0 1.5 0.59 9.9 0.2 2.4 2 0 0 2 2 2 0 Calmodulin binding domain AAA_30 PF13604.1 CBZ23323.1 - 0.044 13.3 1.7 0.085 12.4 0.5 1.8 2 0 0 2 2 2 0 AAA domain Cmc1 PF08583.5 CBZ23324.1 - 2.3e-05 24.0 2.2 3.3e-05 23.5 1.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 CBZ23324.1 - 0.016 15.2 1.4 0.029 14.3 0.8 1.5 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CTDII PF01556.13 CBZ23325.1 - 4.5e-28 96.9 3.9 3.4e-22 78.1 0.1 3.3 3 0 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 CBZ23325.1 - 5.4e-22 77.2 0.6 1.7e-21 75.6 0.5 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CBZ23325.1 - 2.3e-08 33.9 26.1 4.1e-08 33.1 18.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Ribosomal_L16 PF00252.13 CBZ23326.1 - 3.4e-27 94.8 0.3 4.3e-27 94.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e ADK PF00406.17 CBZ23327.1 - 8.2e-39 132.8 0.0 9.9e-39 132.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 CBZ23327.1 - 1.6e-07 31.3 0.0 3.7e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ23327.1 - 1.6e-07 31.6 0.0 2.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ23327.1 - 9.2e-06 26.4 0.1 1.7e-05 25.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 CBZ23327.1 - 0.035 14.0 0.2 0.76 9.6 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_28 PF13521.1 CBZ23327.1 - 0.036 14.0 0.0 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Nop14 PF04147.7 CBZ23331.1 - 0.00027 19.0 31.9 0.00038 18.5 22.1 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.5 CBZ23331.1 - 0.0031 16.6 24.5 0.0043 16.1 17.0 1.2 1 0 0 1 1 1 1 BUD22 Caldesmon PF02029.10 CBZ23331.1 - 0.0033 15.9 11.3 0.0042 15.5 7.8 1.1 1 0 0 1 1 1 1 Caldesmon Daxx PF03344.10 CBZ23331.1 - 0.0054 15.2 22.6 0.0074 14.8 15.6 1.2 1 0 0 1 1 1 1 Daxx Family DUF2201_N PF13203.1 CBZ23331.1 - 0.053 12.6 6.2 0.079 12.1 4.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain SDA1 PF05285.7 CBZ23331.1 - 0.059 12.6 29.5 0.089 12.0 20.5 1.2 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.2 CBZ23331.1 - 0.063 10.9 3.8 0.076 10.6 2.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIF_alpha PF05793.7 CBZ23331.1 - 0.32 9.3 24.8 0.44 8.8 17.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mpp10 PF04006.7 CBZ23331.1 - 1.9 6.7 28.1 2.7 6.2 19.5 1.1 1 0 0 1 1 1 0 Mpp10 protein Astro_capsid PF03115.9 CBZ23331.1 - 2 6.5 8.9 2.2 6.4 6.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF1510 PF07423.6 CBZ23331.1 - 3 7.1 22.3 4.7 6.5 15.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SGT1 PF07093.6 CBZ23331.1 - 3.8 5.7 18.1 5 5.3 12.5 1.2 1 0 0 1 1 1 0 SGT1 protein SAPS PF04499.10 CBZ23331.1 - 4.9 5.6 9.5 6.3 5.3 6.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Na_trans_assoc PF06512.8 CBZ23331.1 - 9.6 6.0 15.0 13 5.6 10.4 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Voltage_CLC PF00654.15 CBZ23332.1 - 7.1e-86 288.4 29.8 7.1e-86 288.4 20.6 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CBZ23332.1 - 6.2e-09 35.5 2.2 0.00049 19.8 0.0 3.6 3 0 0 3 3 3 2 CBS domain TAT_signal PF10518.4 CBZ23332.1 - 0.019 14.9 0.1 0.019 14.9 0.0 4.0 3 0 0 3 3 3 0 TAT (twin-arginine translocation) pathway signal sequence LRR19-TM PF15176.1 CBZ23332.1 - 0.47 10.1 1.7 3.4 7.4 0.8 2.6 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF947 PF06102.7 CBZ23333.1 - 1.5e-10 41.1 9.0 4.3e-10 39.6 6.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF947) DUF1660 PF07874.6 CBZ23333.1 - 0.22 11.8 1.4 0.44 10.8 1.0 1.5 1 0 0 1 1 1 0 Prophage protein (DUF1660) COPI_assoc PF08507.5 CBZ23334.1 - 9.6e-14 51.2 7.6 1.1e-13 51.0 5.3 1.1 1 0 0 1 1 1 1 COPI associated protein DUF4131 PF13567.1 CBZ23334.1 - 0.48 9.8 9.6 2.7 7.3 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Neurensin PF14927.1 CBZ23334.1 - 1.7 7.9 8.6 0.82 9.0 0.1 2.6 1 1 1 2 2 2 0 Neurensin Acyltransferase PF01553.16 CBZ23336.1 - 2.7e-10 39.7 0.1 3.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF2905 PF11146.3 CBZ23336.1 - 0.082 12.8 0.2 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) ERM PF00769.14 CBZ23337.1 - 0.076 12.5 0.3 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family FliG_C PF01706.11 CBZ23338.1 - 0.019 14.9 0.3 0.025 14.5 0.2 1.2 1 0 0 1 1 1 0 FliG C-terminal domain Glyco_transf_21 PF13506.1 CBZ23338.1 - 0.054 12.7 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 Tcf25 PF04910.9 CBZ23339.1 - 1.1e-65 222.0 0.0 1.8e-65 221.2 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 ERM PF00769.14 CBZ23340.1 - 4.1e-05 23.2 16.0 4.1e-05 23.2 11.1 5.5 2 2 3 5 5 5 1 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.3 CBZ23340.1 - 0.0047 16.6 6.1 0.0047 16.6 4.2 7.6 5 3 3 8 8 8 3 TATA element modulatory factor 1 DNA binding Muted PF14942.1 CBZ23341.1 - 0.055 13.3 0.8 0.06 13.2 0.6 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein BTV_NS2 PF04514.7 CBZ23341.1 - 0.058 12.2 0.1 0.063 12.1 0.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 AF0941-like PF14591.1 CBZ23341.1 - 0.17 11.9 1.3 0.22 11.5 0.9 1.2 1 0 0 1 1 1 0 AF0941-like ATP-synt_DE PF00401.15 CBZ23341.1 - 1.6 8.6 5.8 9 6.2 0.7 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain E1-E2_ATPase PF00122.15 CBZ23342.1 - 3.9e-20 71.8 0.7 8.8e-20 70.7 0.5 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CBZ23342.1 - 6.7e-18 65.8 0.0 1.6e-17 64.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ23342.1 - 0.00022 21.4 0.0 0.00049 20.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1664 PF07889.7 CBZ23343.1 - 3.6 7.3 7.0 0.46 10.2 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 CBZ23343.1 - 4.1 5.7 17.3 6 5.2 12.0 1.1 1 0 0 1 1 1 0 AAA domain SCO1-SenC PF02630.9 CBZ23344.1 - 3.1e-41 140.8 0.0 4.2e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 CBZ23344.1 - 0.0089 15.7 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Phage_T4_Ndd PF06591.6 CBZ23346.1 - 0.0096 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 T4-like phage nuclear disruption protein (Ndd) FBPase PF00316.15 CBZ23347.1 - 1.1e-106 356.4 0.1 1.3e-106 356.1 0.1 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase NdhM PF10664.4 CBZ23347.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M DUF3733 PF12534.3 CBZ23347.1 - 0.07 12.4 0.1 0.39 10.0 0.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 RRM_5 PF13893.1 CBZ23349.1 - 3.8e-22 77.8 0.1 7.3e-10 38.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ23349.1 - 2.8e-13 49.2 0.0 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23349.1 - 9.3e-13 47.9 0.0 3.1e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CDC48_2 PF02933.12 CBZ23349.1 - 0.00036 20.0 0.0 0.00067 19.2 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Calcipressin PF04847.7 CBZ23349.1 - 0.0081 15.7 0.4 0.24 10.9 0.1 2.3 2 0 0 2 2 2 1 Calcipressin PolyA_pol PF01743.15 CBZ23351.1 - 1.9e-28 99.2 0.0 3.4e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CBZ23351.1 - 2.2e-07 30.3 0.1 5.5e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A LRR_6 PF13516.1 CBZ23352.1 - 6.1e-07 28.8 0.0 1.9 8.7 0.0 3.6 3 0 0 3 3 3 3 Leucine Rich repeat LRR_4 PF12799.2 CBZ23352.1 - 4.9e-06 26.0 0.0 0.0013 18.2 0.1 2.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ23352.1 - 0.01 15.7 0.1 15 6.1 0.0 4.2 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_8 PF13855.1 CBZ23352.1 - 0.019 14.6 0.1 0.28 10.9 0.1 2.5 2 1 1 3 3 3 0 Leucine rich repeat ExoD PF06055.7 CBZ23352.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD Pkinase PF00069.20 CBZ23353.1 - 4.4e-32 111.2 0.0 5.8e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23353.1 - 9.6e-18 64.1 0.0 1.4e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ23353.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.14 CBZ23355.1 - 4.4e-143 476.4 0.0 5e-143 476.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CBZ23355.1 - 0.011 16.0 0.1 0.064 13.6 0.0 2.1 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) EcoRII-C PF09019.6 CBZ23355.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 EcoRII C terminal Arf PF00025.16 CBZ23358.1 - 3.1e-54 182.8 0.0 3.5e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CBZ23358.1 - 1.5e-08 33.8 0.9 4.2e-06 25.6 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 CBZ23358.1 - 2.2e-08 33.5 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ23358.1 - 5.8e-08 33.2 0.0 7.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CBZ23358.1 - 2.3e-07 30.3 0.0 2.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CBZ23358.1 - 3.4e-06 27.0 0.0 6.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBZ23358.1 - 1.8e-05 24.0 0.0 2.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ23358.1 - 2.7e-05 23.6 0.1 0.0061 16.0 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBZ23358.1 - 0.043 13.0 0.0 0.26 10.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B cobW PF02492.14 CBZ23358.1 - 0.043 13.2 0.1 4 6.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 CBZ23358.1 - 0.048 13.0 0.2 0.1 11.9 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 CBZ23358.1 - 0.094 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Bacillus_HBL PF05791.6 CBZ23359.1 - 0.0052 16.1 2.9 0.0052 16.1 2.0 5.4 3 1 3 6 6 6 1 Bacillus haemolytic enterotoxin (HBL) Flu_NS2 PF00601.14 CBZ23360.1 - 0.0092 16.1 1.2 6.5 7.0 0.2 3.8 1 1 1 2 2 2 2 Influenza non-structural protein (NS2) MVP_shoulder PF11978.3 CBZ23361.1 - 2.1e-50 169.5 0.1 4e-50 168.6 0.1 1.5 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.13 CBZ23361.1 - 5.9e-47 157.4 8.2 1.2e-11 44.4 0.1 6.2 6 0 0 6 6 6 5 Major Vault Protein repeat DUF3601 PF12208.3 CBZ23361.1 - 0.0078 16.1 0.0 5.3 7.0 0.0 3.5 2 1 1 3 3 3 1 Domain of unknown function (DUF3601) Dynein_light PF01221.13 CBZ23362.1 - 2e-31 107.8 0.4 2.2e-31 107.6 0.3 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Vasohibin PF14822.1 CBZ23362.1 - 0.037 13.0 0.2 0.044 12.8 0.1 1.2 1 1 0 1 1 1 0 Vasohibin Rrp15p PF07890.7 CBZ23363.1 - 3.8e-07 30.2 15.5 6.4e-07 29.4 10.7 1.4 1 1 0 1 1 1 1 Rrp15p NUDIX PF00293.23 CBZ23364.1 - 6.5e-14 51.7 0.0 9.1e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.23 CBZ23365.1 - 1.2e-29 103.1 0.1 1.9e-29 102.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Plus-3 PF03126.13 CBZ23365.1 - 0.0003 20.8 0.0 0.00063 19.7 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain Metallophos_2 PF12850.2 CBZ23365.1 - 0.0005 19.9 0.0 0.00093 19.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Methyltransf_4 PF02390.12 CBZ23367.1 - 0.0039 16.2 0.0 0.0055 15.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase GspL_C PF12693.2 CBZ23367.1 - 0.11 12.2 0.3 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 GspL periplasmic domain NAD_binding_7 PF13241.1 CBZ23367.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding Pkinase PF00069.20 CBZ23368.1 - 1.3e-54 185.1 0.1 2.8e-54 183.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23368.1 - 3e-29 101.8 0.0 2.5e-27 95.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ23368.1 - 0.0002 21.1 0.0 0.002 17.8 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ23368.1 - 0.00088 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBZ23368.1 - 0.0082 15.4 0.1 0.013 14.8 0.1 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 CBZ23368.1 - 0.016 14.6 0.9 0.032 13.5 0.7 1.5 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 CBZ23368.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DEAD PF00270.24 CBZ23369.1 - 8.5e-39 132.7 0.0 1.9e-37 128.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase GUCT PF08152.7 CBZ23369.1 - 4.8e-27 93.7 0.0 9.7e-27 92.8 0.0 1.5 1 0 0 1 1 1 1 GUCT (NUC152) domain Helicase_C PF00271.26 CBZ23369.1 - 3.3e-24 84.5 0.0 1e-23 83.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ23369.1 - 0.0034 17.2 0.1 0.069 12.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit LRR_6 PF13516.1 CBZ23370.1 - 4.5e-31 103.3 18.5 0.00074 19.3 0.2 10.2 9 1 1 10 10 10 8 Leucine Rich repeat LRR_4 PF12799.2 CBZ23370.1 - 9.8e-12 44.2 10.6 8.8e-06 25.2 0.0 6.1 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ23370.1 - 3e-11 41.7 5.4 0.12 12.5 0.0 7.4 7 0 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 CBZ23370.1 - 3.3e-05 23.3 13.5 5.8 7.5 0.0 7.8 8 0 0 8 8 8 2 Leucine rich repeat LRR_8 PF13855.1 CBZ23370.1 - 4e-05 23.2 10.5 0.058 13.1 0.2 4.8 4 2 1 5 5 5 3 Leucine rich repeat 2H-phosphodiest PF08975.5 CBZ23371.1 - 0.021 14.5 0.4 0.066 12.9 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) TEX12 PF15219.1 CBZ23371.1 - 0.035 14.0 0.5 0.035 14.0 0.4 2.4 3 0 0 3 3 3 0 Testis-expressed 12 Lebercilin PF15619.1 CBZ23371.1 - 0.52 9.6 46.7 0.3 10.4 13.9 2.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease 2-oxoacid_dh PF00198.18 CBZ23373.1 - 6.1e-80 267.8 0.2 7.7e-80 267.4 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CBZ23373.1 - 6.8e-16 57.6 2.6 7.1e-16 57.6 0.2 2.2 3 0 0 3 3 3 1 Biotin-requiring enzyme E3_binding PF02817.12 CBZ23373.1 - 7.1e-15 54.3 0.1 2e-14 52.9 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CBZ23373.1 - 0.014 15.0 2.2 7.3 6.3 0.1 3.3 3 0 0 3 3 3 0 Biotin-lipoyl like Fip1 PF05182.8 CBZ23374.1 - 3.1e-21 74.3 0.2 5e-21 73.7 0.1 1.3 1 0 0 1 1 1 1 Fip1 motif zf-CCCH PF00642.19 CBZ23374.1 - 6.3e-11 41.6 2.9 1.3e-10 40.7 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 CBZ23375.1 - 6e-16 58.4 0.0 4.7e-14 52.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ23375.1 - 9.3e-06 24.9 0.0 3.2e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.11 CBZ23375.1 - 0.00022 20.3 0.0 0.00045 19.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 CBZ23375.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 CBZ23375.1 - 0.023 15.1 0.0 0.14 12.6 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 CBZ23375.1 - 0.13 12.0 0.7 0.38 10.5 0.0 2.2 2 0 0 2 2 2 0 Dynamin family GTP_EFTU PF00009.22 CBZ23375.1 - 0.15 11.4 0.1 6.7 6.1 0.0 3.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DSPc PF00782.15 CBZ23377.1 - 8.9e-34 115.9 0.1 1.4e-33 115.2 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ23377.1 - 4.5e-05 22.9 0.1 9.3e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 CBZ23377.1 - 0.00065 19.0 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 CBZ23377.1 - 0.0017 17.3 0.1 0.0026 16.7 0.1 1.2 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase CDKN3 PF05706.7 CBZ23377.1 - 0.044 13.2 0.0 0.5 9.7 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Myotub-related PF06602.9 CBZ23377.1 - 0.056 12.2 0.1 0.086 11.5 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Fe_hyd_lg_C PF02906.9 CBZ23378.1 - 1.9e-61 207.8 0.0 3e-60 203.9 0.0 2.2 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain DUF742 PF05331.6 CBZ23378.1 - 0.047 13.2 0.7 1.6 8.3 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF742) PDZ_2 PF13180.1 CBZ23379.1 - 0.0027 17.5 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBZ23379.1 - 0.004 17.2 0.0 0.0084 16.2 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) MAD PF05557.8 CBZ23379.1 - 2.2 6.2 87.2 0.62 8.0 8.5 6.4 1 1 5 6 6 6 0 Mitotic checkpoint protein FtsK_SpoIIIE_N PF12538.3 CBZ23380.1 - 2.5e-05 24.3 0.0 93 3.1 0.0 9.2 1 1 11 15 15 15 0 DNA transporter PDZ_2 PF13180.1 CBZ23380.1 - 0.0036 17.1 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBZ23380.1 - 0.005 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ank PF00023.25 CBZ23382.1 - 6.4e-07 28.8 0.0 1.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 CBZ23382.1 - 5e-06 26.7 0.3 5.2e-05 23.5 0.0 2.6 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBZ23382.1 - 3.3e-05 23.7 0.1 0.00016 21.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CBZ23382.1 - 0.0002 21.4 0.0 0.00067 19.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBZ23382.1 - 0.0021 18.4 0.1 0.0052 17.2 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) SPX PF03105.14 CBZ23382.1 - 1.5 8.5 4.4 1.1 9.0 2.2 1.4 1 1 0 1 1 1 0 SPX domain PTPLA PF04387.9 CBZ23384.1 - 1.5e-57 193.5 6.9 2e-57 193.2 4.8 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Lig_chan PF00060.21 CBZ23384.1 - 1.1 8.9 4.5 2.7 7.7 0.3 2.2 1 1 0 2 2 2 0 Ligand-gated ion channel P16-Arc PF04699.9 CBZ23385.1 - 1.1e-05 25.4 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Mito_carr PF00153.22 CBZ23386.1 - 5.3e-46 154.2 6.3 6.6e-15 54.5 0.0 4.9 5 1 0 5 5 5 3 Mitochondrial carrier protein Glutaredoxin PF00462.19 CBZ23388.1 - 1.8e-15 56.6 0.0 2.5e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Pil1 PF13805.1 CBZ23388.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.3 1 1 0 1 1 1 0 Eisosome component PIL1 MCM PF00493.18 CBZ23390.1 - 1e-89 300.6 0.0 1.7e-79 267.0 0.0 2.1 2 0 0 2 2 2 2 MCM2/3/5 family AAA_5 PF07728.9 CBZ23390.1 - 1e-08 34.9 0.0 1.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBZ23390.1 - 0.0002 20.5 0.2 0.067 12.3 0.1 2.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBZ23390.1 - 0.00081 18.9 0.0 0.0022 17.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBZ23390.1 - 0.0094 15.4 0.1 0.04 13.3 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 CBZ23390.1 - 0.042 14.0 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBZ23390.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Ribosomal_S11 PF00411.14 CBZ23391.1 - 0.0042 17.2 0.0 0.016 15.3 0.0 2.0 1 0 0 1 1 1 1 Ribosomal protein S11 Pyr_redox_2 PF07992.9 CBZ23392.1 - 2.2e-33 115.8 4.0 3.8e-32 111.8 2.8 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBZ23392.1 - 3.2e-28 97.9 0.1 6.2e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBZ23392.1 - 1.4e-19 70.3 0.2 4.6e-16 58.9 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBZ23392.1 - 7.3e-09 35.9 0.4 4.3e-05 23.6 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBZ23392.1 - 2.5e-06 26.2 0.6 0.045 12.2 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 CBZ23392.1 - 6.7e-05 21.9 3.1 0.00055 18.8 1.2 2.5 2 1 1 3 3 3 1 FAD binding domain GIDA PF01134.17 CBZ23392.1 - 0.0044 15.9 0.7 0.0074 15.1 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 CBZ23392.1 - 0.012 14.4 2.6 0.9 8.3 0.0 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CBZ23392.1 - 0.03 14.0 0.2 0.093 12.4 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding PALP PF00291.20 CBZ23392.1 - 0.032 13.4 0.1 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DEAD PF00270.24 CBZ23393.1 - 6.5e-40 136.3 0.0 1.1e-39 135.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ23393.1 - 5.5e-22 77.4 0.0 1.1e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ23393.1 - 8.6e-05 22.4 0.0 0.00059 19.7 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit YaeQ PF07152.7 CBZ23394.1 - 0.0034 16.7 0.1 2.4 7.4 0.0 2.2 2 0 0 2 2 2 2 YaeQ protein Pkinase PF00069.20 CBZ23396.1 - 3.2e-67 226.4 0.0 4e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23396.1 - 3.3e-49 167.3 0.0 4.8e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MORN PF02493.15 CBZ23396.1 - 8.4e-43 141.6 47.7 3.5e-10 38.9 2.6 8.6 8 0 0 8 8 8 8 MORN repeat Kinase-like PF14531.1 CBZ23396.1 - 0.00081 18.4 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBZ23396.1 - 0.052 12.8 0.0 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 RIO1 family ABC1 PF03109.11 CBZ23396.1 - 0.2 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 ABC1 family SMC_N PF02463.14 CBZ23397.1 - 3e-59 199.9 0.0 5.1e-59 199.1 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBZ23397.1 - 3.8e-15 56.6 0.1 5.1e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CBZ23397.1 - 6.5e-13 49.4 12.7 6.5e-13 49.4 8.8 6.4 2 2 1 3 3 3 1 AAA domain SMC_hinge PF06470.8 CBZ23397.1 - 1.3e-11 44.4 0.1 8.3e-11 41.9 0.1 2.5 1 1 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 CBZ23397.1 - 4.5e-05 22.8 0.0 0.00011 21.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CBZ23397.1 - 0.00055 19.0 0.2 0.0016 17.5 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 CBZ23397.1 - 0.027 14.7 17.3 1.3 9.3 2.2 5.8 3 2 0 3 3 3 0 ABC transporter TPR_2 PF07719.12 CBZ23398.1 - 4.7e-20 69.8 19.2 0.00047 19.8 0.1 10.1 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ23398.1 - 6.5e-18 64.1 23.7 1.2e-07 31.3 0.1 7.5 4 1 3 8 8 8 4 TPR repeat TPR_1 PF00515.23 CBZ23398.1 - 1.4e-14 52.9 9.2 0.022 14.3 0.1 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ23398.1 - 4.2e-14 52.7 49.3 0.00031 21.3 0.3 9.2 6 1 4 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ23398.1 - 4.5e-14 51.6 37.4 0.00012 22.4 0.1 10.8 7 2 4 11 11 10 5 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ23398.1 - 1e-11 44.5 26.8 0.0078 16.1 0.2 8.4 5 1 4 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ23398.1 - 2.3e-10 40.6 33.6 6.4e-07 29.6 0.2 8.1 7 2 1 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 CBZ23398.1 - 2.6e-10 40.2 23.4 0.00068 19.7 0.1 6.1 5 1 1 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBZ23398.1 - 2.8e-10 39.5 6.7 0.00067 19.6 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ23398.1 - 1.8e-06 27.2 0.0 0.58 10.0 0.0 6.9 8 0 0 8 8 8 1 Tetratricopeptide repeat BTAD PF03704.12 CBZ23398.1 - 0.00015 22.1 3.1 0.00015 22.1 2.1 4.6 4 1 0 4 4 4 1 Bacterial transcriptional activator domain TPR_9 PF13371.1 CBZ23398.1 - 0.00021 21.1 0.8 0.00021 21.1 0.5 7.1 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ23398.1 - 0.0047 17.3 26.2 1.7 9.2 0.1 9.1 11 0 0 11 11 8 1 Tetratricopeptide repeat NARP1 PF12569.3 CBZ23398.1 - 0.0099 14.6 1.3 0.73 8.5 0.1 2.4 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 CBZ23398.1 - 0.052 13.4 7.4 0.13 12.1 0.1 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Tctex-1 PF03645.8 CBZ23399.1 - 1.4e-25 89.1 1.0 1.5e-25 88.9 0.7 1.0 1 0 0 1 1 1 1 Tctex-1 family Metallophos PF00149.23 CBZ23400.1 - 0.00018 20.9 0.0 0.00064 19.1 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Skp1 PF01466.14 CBZ23402.1 - 0.00058 19.8 0.0 0.00089 19.2 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain NGP1NT PF08153.7 CBZ23403.1 - 6.9e-45 152.1 1.0 6.9e-45 152.1 0.7 2.3 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CBZ23403.1 - 1.2e-19 70.4 1.6 3.9e-16 59.0 0.0 3.0 3 1 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ23403.1 - 2.8e-05 23.4 0.1 0.00018 20.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBZ23403.1 - 0.00038 19.9 0.0 0.27 10.6 0.0 3.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CBZ23403.1 - 0.0021 18.5 0.4 0.56 10.7 0.0 3.5 3 0 0 3 3 3 1 Miro-like protein DUF258 PF03193.11 CBZ23403.1 - 0.0033 16.6 0.0 0.0071 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBZ23403.1 - 0.0093 15.8 12.7 0.44 10.3 0.0 5.0 3 2 1 4 4 4 2 Dynamin family AAA_16 PF13191.1 CBZ23403.1 - 0.019 14.9 2.6 0.053 13.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain MobB PF03205.9 CBZ23403.1 - 0.22 11.2 3.3 0.57 9.8 0.1 2.7 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MFS_1 PF07690.11 CBZ23405.1 - 2.4e-25 88.9 43.0 7.2e-19 67.7 7.2 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily ATP-synt_G PF04718.10 CBZ23406.1 - 0.14 12.8 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit DUF2755 PF10954.3 CBZ23406.1 - 0.2 11.4 1.0 0.32 10.7 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) ATP-synt_ab PF00006.20 CBZ23407.1 - 6.5e-69 231.7 0.1 9.6e-69 231.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain His_kinase PF06580.8 CBZ23407.1 - 0.064 13.1 2.0 6 6.8 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase ATP-synt_ab_C PF00306.22 CBZ23407.1 - 0.096 13.1 0.0 0.31 11.5 0.0 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab PF00006.20 CBZ23408.1 - 9e-69 231.2 0.1 1.3e-68 230.6 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain His_kinase PF06580.8 CBZ23408.1 - 0.079 12.8 1.8 7.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase ATP-synt_ab_C PF00306.22 CBZ23408.1 - 0.13 12.6 0.0 0.44 11.0 0.0 1.9 1 1 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain ADH_zinc_N PF00107.21 CBZ23409.1 - 4.8e-07 29.3 0.1 1e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBZ23409.1 - 0.0039 16.9 0.1 0.011 15.5 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain LSM PF01423.17 CBZ23411.1 - 2.8e-06 26.7 0.1 2e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 LSM domain Pkinase PF00069.20 CBZ23412.1 - 5.1e-70 235.5 0.0 5.9e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23412.1 - 7.6e-32 110.3 0.0 1e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ23412.1 - 0.00031 19.8 0.0 0.00052 19.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ23412.1 - 0.0042 16.8 0.0 0.022 14.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBZ23412.1 - 0.099 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Motile_Sperm PF00635.21 CBZ23413.1 - 0.00093 18.8 0.0 0.0046 16.5 0.0 2.0 2 0 0 2 2 2 1 MSP (Major sperm protein) domain NDUF_B5 PF09781.4 CBZ23414.1 - 0.098 11.9 1.4 0.18 11.0 1.0 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit DUF4064 PF13273.1 CBZ23415.1 - 0.048 13.7 0.7 6.2 6.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF2106 PF09879.4 CBZ23415.1 - 0.15 11.3 0.3 0.68 9.2 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2106) DEAD PF00270.24 CBZ23416.1 - 8e-30 103.5 0.1 1.5e-15 57.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ23416.1 - 2.5e-21 75.3 0.1 4.7e-21 74.4 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ23416.1 - 5.6e-05 23.0 0.0 0.00022 21.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PBP1_TM PF14812.1 CBZ23416.1 - 3.7 7.9 13.4 0.75 10.1 5.4 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal COG4 PF08318.7 CBZ23417.1 - 1.7e-36 125.6 0.1 1.8e-32 112.4 0.0 2.8 3 0 0 3 3 3 2 COG4 transport protein RINT1_TIP1 PF04437.8 CBZ23417.1 - 0.027 13.0 1.7 0.097 11.2 0.2 2.4 2 1 0 2 2 2 0 RINT-1 / TIP-1 family STAT_alpha PF01017.15 CBZ23417.1 - 0.036 13.8 1.3 1.1 8.9 0.0 2.9 2 1 1 3 3 3 0 STAT protein, all-alpha domain Surp PF01805.15 CBZ23418.1 - 1.5e-08 34.1 0.0 2.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Surp module ubiquitin PF00240.18 CBZ23419.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family Kinesin PF00225.18 CBZ23420.1 - 2.5e-87 292.7 0.0 4.2e-87 291.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Ank_2 PF12796.2 CBZ23421.1 - 1.1e-48 163.5 13.2 2.9e-10 40.3 0.0 11.1 8 4 5 14 14 13 10 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ23421.1 - 4.8e-32 109.7 19.2 2.3e-06 27.9 0.1 14.5 12 3 2 15 15 15 8 Ankyrin repeats (many copies) Ank PF00023.25 CBZ23421.1 - 5.3e-32 108.0 39.4 7.6e-06 25.4 0.0 16.7 18 0 0 18 18 18 12 Ankyrin repeat Ank_5 PF13857.1 CBZ23421.1 - 1.8e-28 97.9 31.0 4.9e-06 26.6 0.1 13.1 13 1 1 14 14 14 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ23421.1 - 7.6e-26 87.5 24.4 0.00023 21.0 0.0 15.8 17 0 0 17 17 17 7 Ankyrin repeat LRR_4 PF12799.2 CBZ23422.1 - 0.00029 20.3 0.3 0.00082 18.9 0.2 1.8 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBZ23422.1 - 0.00054 19.7 1.3 2.7 8.5 0.0 4.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_8 PF13855.1 CBZ23422.1 - 0.00091 18.9 0.3 0.0022 17.6 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_6 PF13516.1 CBZ23422.1 - 0.0067 16.3 0.3 6.9 7.0 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.28 CBZ23422.1 - 0.024 14.5 2.7 1.2 9.3 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat Nitroreductase PF00881.19 CBZ23423.1 - 7.6e-31 107.1 0.0 1.1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Mtc PF03820.12 CBZ23425.1 - 3.5e-71 239.3 0.1 3.9e-71 239.2 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SHIPPO-rpt PF07004.7 CBZ23426.1 - 9.7e-50 165.0 180.0 0.0085 16.9 0.7 37.3 38 0 0 38 38 38 30 Sperm-tail PG-rich repeat Cyclin PF08613.6 CBZ23428.1 - 3.5e-18 66.4 0.0 1.3e-17 64.6 0.0 2.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBZ23428.1 - 0.0014 18.1 0.0 0.0042 16.6 0.0 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain DSPc PF00782.15 CBZ23429.1 - 2.9e-19 68.9 0.0 1.3e-06 28.0 0.0 3.3 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain DUF605 PF04652.11 CBZ23431.1 - 3.1e-78 263.8 25.2 4.8e-78 263.1 17.5 1.3 1 1 0 1 1 1 1 Vta1 like DUF2413 PF10310.4 CBZ23431.1 - 0.04 12.7 0.2 0.086 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PAT1 PF09770.4 CBZ23431.1 - 1.4 7.0 19.7 1.7 6.8 13.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Wyosine_form PF08608.7 CBZ23432.1 - 2.2e-21 75.7 1.5 3.3e-15 55.9 0.0 3.1 3 0 0 3 3 3 2 Wyosine base formation Radical_SAM PF04055.16 CBZ23432.1 - 1.7e-20 73.8 0.0 2.9e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.20 CBZ23432.1 - 1.6e-11 44.3 0.1 5.1e-10 39.4 0.0 2.4 1 1 1 2 2 2 1 Flavodoxin FEZ PF07763.8 CBZ23432.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 FEZ-like protein Kinesin PF00225.18 CBZ23433.1 - 4.2e-80 268.9 0.0 5e-53 179.9 0.3 2.2 2 0 0 2 2 2 2 Kinesin motor domain MAM33 PF02330.11 CBZ23436.1 - 1.5e-08 34.6 0.0 3.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF3446 PF11928.3 CBZ23436.1 - 0.074 13.2 4.1 4.5 7.5 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) zf-MYND PF01753.13 CBZ23437.1 - 1.1e-10 41.1 12.1 1.1e-10 41.1 8.4 1.9 2 0 0 2 2 2 1 MYND finger DUF1688 PF07958.6 CBZ23437.1 - 0.011 14.3 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) DUF957 PF06117.6 CBZ23437.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 Enterobacterial protein of unknown function (DUF957) Got1 PF04178.7 CBZ23438.1 - 1.6e-31 108.8 13.6 1.9e-31 108.6 9.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family 7tm_3 PF00003.17 CBZ23438.1 - 0.00011 21.6 7.7 0.00011 21.6 5.3 1.4 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR AgrB PF04647.10 CBZ23438.1 - 0.1 11.6 5.9 0.13 11.2 4.1 1.2 1 0 0 1 1 1 0 Accessory gene regulator B PrgI PF12666.2 CBZ23438.1 - 2.8 8.1 8.8 49 4.1 5.5 2.5 1 1 0 1 1 1 0 PrgI family protein DUF454 PF04304.8 CBZ23438.1 - 7.7 6.6 13.1 10 6.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DUF4064 PF13273.1 CBZ23438.1 - 9.6 6.3 9.3 18 5.5 5.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) PNP_UDP_1 PF01048.15 CBZ23440.1 - 5.4e-36 123.7 0.4 6.6e-36 123.4 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily zf-C2HC_2 PF13913.1 CBZ23442.1 - 3.5e-14 52.0 9.5 7.3e-09 35.0 1.6 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Cys_rich_CPXG PF14255.1 CBZ23442.1 - 0.094 12.5 0.6 15 5.5 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-C2H2 PF00096.21 CBZ23442.1 - 0.15 12.4 1.6 7.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-RING_3 PF14369.1 CBZ23442.1 - 0.36 10.8 1.8 1 9.4 0.2 2.3 2 0 0 2 2 2 0 zinc-finger Sgf11 PF08209.6 CBZ23442.1 - 0.53 9.6 4.1 0.25 10.7 0.3 2.1 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) CPSF_A PF03178.10 CBZ23446.1 - 1.9e-18 66.6 0.0 7.3e-13 48.2 0.0 3.3 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 CBZ23446.1 - 1.7e-07 29.7 0.0 0.006 14.7 0.0 4.3 5 1 0 5 5 5 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term NOA36 PF06524.7 CBZ23446.1 - 1.8 7.7 5.1 2.9 7.0 3.5 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 CBZ23446.1 - 1.9 8.7 9.2 4.1 7.6 6.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LRR_8 PF13855.1 CBZ23447.1 - 9.9e-08 31.6 4.8 0.00017 21.2 0.4 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CBZ23447.1 - 9.5e-06 25.1 0.4 0.00018 21.0 0.3 2.6 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ23447.1 - 0.00012 21.6 1.3 12 6.4 0.0 5.4 6 0 0 6 6 6 1 Leucine Rich Repeat LRRNT_2 PF08263.7 CBZ23448.1 - 0.049 13.6 0.7 0.1 12.6 0.5 1.5 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Flagellar_rod PF05149.7 CBZ23449.1 - 2.9e-99 331.9 31.9 2.9e-99 331.9 22.1 2.2 3 0 0 3 3 3 1 Paraflagellar rod protein DUF3456 PF11938.3 CBZ23449.1 - 0.24 11.4 7.7 0.025 14.5 1.2 2.4 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP UQ_con PF00179.21 CBZ23450.1 - 1.5e-13 50.3 0.0 2.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PAT1 PF09770.4 CBZ23450.1 - 7 4.7 17.6 9.4 4.3 12.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kinesin-relat_1 PF12711.2 CBZ23451.1 - 0.0015 18.8 0.2 0.27 11.6 0.0 2.5 2 0 0 2 2 2 2 Kinesin motor Peptidase_M28 PF04389.12 CBZ23452.1 - 2.2e-17 63.3 0.9 0.0001 22.0 0.2 3.5 3 0 0 3 3 3 3 Peptidase family M28 Peptidase_M49 PF03571.10 CBZ23453.1 - 6.8e-215 714.3 0.0 8.4e-215 714.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF1930 PF09122.5 CBZ23454.1 - 2e-36 123.6 0.1 3.6e-36 122.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) Rhodanese PF00581.15 CBZ23454.1 - 5.1e-17 62.2 0.0 2.1e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Complex1_51K PF01512.12 CBZ23455.1 - 5.4e-45 152.8 0.0 1e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 CBZ23455.1 - 2e-18 65.2 0.1 4.1e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 CBZ23455.1 - 5.5e-08 32.5 0.0 1.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 SLBB domain zf-C3HC4_3 PF13920.1 CBZ23457.1 - 0.00024 20.7 6.7 0.00041 19.9 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C2HC5 PF06221.8 CBZ23457.1 - 0.0016 18.1 3.6 0.0016 18.1 2.5 1.7 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type zf-RING_5 PF14634.1 CBZ23457.1 - 0.0019 17.8 7.4 0.0032 17.1 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBZ23457.1 - 0.66 9.8 10.5 1.6 8.6 7.3 1.6 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ23457.1 - 2.9 8.0 10.3 5.4 7.1 7.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0020 PF01170.13 CBZ23458.1 - 5.6e-13 48.8 0.0 2.5e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CBZ23458.1 - 5.7e-10 39.2 0.0 1.5e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 CBZ23458.1 - 0.0021 17.1 0.0 0.015 14.3 0.0 2.2 3 0 0 3 3 3 1 N-6 DNA Methylase N6_N4_Mtase PF01555.13 CBZ23458.1 - 0.0046 16.4 0.0 0.037 13.4 0.0 2.1 2 0 0 2 2 2 1 DNA methylase PsiA PF06952.6 CBZ23459.1 - 0.0097 14.9 1.9 0.017 14.1 1.3 1.3 1 0 0 1 1 1 1 PsiA protein Cren7 PF11520.3 CBZ23459.1 - 0.025 14.1 0.1 0.056 13.0 0.1 1.5 1 0 0 1 1 1 0 Chromatin protein Cren7 Band_7 PF01145.20 CBZ23461.1 - 1.8e-27 96.4 0.1 1.8e-27 96.4 0.1 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBZ23461.1 - 0.056 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF3498 PF12004.3 CBZ23462.1 - 0.00019 20.7 0.8 0.00019 20.7 0.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3498) IncA PF04156.9 CBZ23462.1 - 2.3 7.7 5.3 1.7 8.2 1.3 2.0 2 0 0 2 2 2 0 IncA protein AFG1_ATPase PF03969.11 CBZ23463.1 - 4.6e-79 265.8 0.3 1.9e-72 244.0 0.0 3.0 2 1 1 3 3 3 3 AFG1-like ATPase AAA_22 PF13401.1 CBZ23463.1 - 0.0035 17.4 0.0 0.0067 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CBZ23463.1 - 0.033 13.1 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CBZ23463.1 - 0.066 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AFG1_ATPase PF03969.11 CBZ23464.1 - 3.8e-60 203.6 0.0 1e-54 185.7 0.0 2.0 1 1 1 2 2 2 2 AFG1-like ATPase Lectin_leg-like PF03388.8 CBZ23465.1 - 3.7e-11 42.5 0.0 7.4e-06 25.2 0.0 3.2 2 1 0 2 2 2 2 Legume-like lectin family MORN PF02493.15 CBZ23466.1 - 3.9e-26 89.1 32.6 7.9e-08 31.5 1.2 7.4 7 0 0 7 7 7 5 MORN repeat Rad21_Rec8_N PF04825.8 CBZ23467.1 - 4.9e-30 103.7 0.1 1.1e-29 102.6 0.1 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CBZ23467.1 - 2.3e-07 29.8 0.4 2.5e-06 26.5 0.0 2.6 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CBZ23467.1 - 0.0001 22.0 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 2 ScpA/B protein Methyltransf_31 PF13847.1 CBZ23468.1 - 6.5e-11 42.0 0.0 7.5e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ23468.1 - 3.9e-09 37.0 0.0 3.1e-08 34.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ23468.1 - 2.4e-08 34.3 0.0 7e-08 32.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ23468.1 - 8.1e-07 29.4 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 CBZ23468.1 - 9.8e-06 25.0 0.0 1.7e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_8 PF05148.10 CBZ23468.1 - 1.2e-05 25.1 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase TPMT PF05724.6 CBZ23468.1 - 2.5e-05 23.8 0.0 0.00062 19.2 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 CBZ23468.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ23468.1 - 0.00083 19.6 0.0 0.0018 18.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBZ23468.1 - 0.002 17.2 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 CBZ23468.1 - 0.0023 17.0 0.0 0.0078 15.3 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 CBZ23468.1 - 0.0034 17.0 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ23468.1 - 0.0092 15.3 0.0 0.037 13.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBZ23468.1 - 0.015 15.3 0.0 0.096 12.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 CBZ23468.1 - 0.02 13.9 0.0 0.03 13.4 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Pox_MCEL PF03291.11 CBZ23468.1 - 0.033 13.0 0.0 0.064 12.1 0.0 1.5 1 1 0 1 1 1 0 mRNA capping enzyme EutQ PF06249.7 CBZ23468.1 - 0.039 13.4 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Spermine_synth PF01564.12 CBZ23468.1 - 0.042 12.7 0.0 0.086 11.7 0.0 1.4 1 1 0 1 1 1 0 Spermine/spermidine synthase RRM_1 PF00076.17 CBZ23469.1 - 1.1e-08 34.6 0.0 0.014 15.0 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23469.1 - 1.7e-05 24.7 0.0 0.078 12.9 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) UPF0104 PF03706.8 CBZ23470.1 - 0.031 13.5 0.2 0.035 13.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) vATP-synt_AC39 PF01992.11 CBZ23472.1 - 4.1e-62 210.2 0.1 4.6e-62 210.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit LRR_4 PF12799.2 CBZ23473.1 - 3.8e-13 48.7 3.6 0.00094 18.7 0.0 5.6 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ23473.1 - 2.7e-07 29.6 12.8 1.6 9.0 0.0 6.7 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.1 CBZ23473.1 - 1.4e-06 27.9 5.2 0.12 12.1 0.0 5.6 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.1 CBZ23473.1 - 6.2e-05 22.6 12.6 0.23 11.6 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich repeat ATG16 PF08614.6 CBZ23473.1 - 0.012 15.4 6.7 0.024 14.4 4.7 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) LRR_9 PF14580.1 CBZ23473.1 - 0.014 14.9 2.5 0.016 14.7 0.1 2.0 2 0 0 2 2 2 0 Leucine-rich repeat Golgin_A5 PF09787.4 CBZ23473.1 - 0.041 12.4 6.1 0.079 11.4 4.2 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 IncA PF04156.9 CBZ23473.1 - 0.049 13.2 6.6 0.089 12.3 4.6 1.3 1 0 0 1 1 1 0 IncA protein Pox_A11 PF05061.8 CBZ23473.1 - 0.099 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein LRR_7 PF13504.1 CBZ23473.1 - 0.11 12.7 19.4 12 6.5 0.0 6.6 7 0 0 7 7 6 0 Leucine rich repeat Atg14 PF10186.4 CBZ23473.1 - 0.5 9.2 7.7 0.76 8.6 5.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 CBZ23473.1 - 0.85 9.5 10.9 1.7 8.5 7.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CorA PF01544.13 CBZ23473.1 - 2.3 7.1 7.4 3.6 6.5 5.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PEHE PF15275.1 CBZ23473.1 - 2.4 8.6 5.1 0.51 10.8 0.7 2.0 2 0 0 2 2 2 0 PEHE domain Spc7 PF08317.6 CBZ23473.1 - 3.8 6.0 6.6 5.8 5.4 4.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ELO PF01151.13 CBZ23474.1 - 2.9e-47 161.0 28.2 4.2e-47 160.5 19.5 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family DUF346 PF03984.8 CBZ23475.1 - 0.018 14.5 0.8 0.018 14.5 0.6 2.1 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) Med3 PF11593.3 CBZ23476.1 - 0.0015 17.8 1.7 0.0015 17.8 1.2 3.8 4 1 0 4 4 4 1 Mediator complex subunit 3 fungal Prefoldin_2 PF01920.15 CBZ23477.1 - 2.7e-19 68.8 4.2 4.3e-19 68.2 2.7 1.5 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 CBZ23477.1 - 0.54 9.9 5.9 0.21 11.2 1.1 2.3 2 1 1 3 3 3 0 Prefoldin subunit ATG16 PF08614.6 CBZ23477.1 - 0.91 9.3 11.3 4.6 7.0 3.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 CBZ23477.1 - 0.92 9.0 8.2 2 7.9 5.7 1.6 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 CBZ23477.1 - 0.92 8.4 7.7 3.8 6.4 1.9 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 NAP PF00956.13 CBZ23477.1 - 0.97 8.5 4.6 0.72 8.9 1.5 1.8 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) DUF3847 PF12958.2 CBZ23477.1 - 1.2 8.9 12.1 0.22 11.2 3.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3847) DUF972 PF06156.8 CBZ23477.1 - 1.3 9.3 7.5 3.7 7.9 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 CBZ23477.1 - 2.4 7.8 7.8 3.5 7.3 1.7 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Osmo_CC PF08946.5 CBZ23477.1 - 3 7.9 12.6 1.3 9.1 3.2 3.6 2 2 0 2 2 2 0 Osmosensory transporter coiled coil OmpH PF03938.9 CBZ23477.1 - 4.1 7.3 14.1 12 5.7 9.8 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) LRR_4 PF12799.2 CBZ23478.1 - 2.7e-32 109.8 16.8 1.3e-07 31.0 1.0 6.7 4 1 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ23478.1 - 5.8e-21 74.0 24.7 1.6e-08 34.1 0.6 5.9 4 3 2 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 CBZ23478.1 - 1.1e-14 52.2 22.4 0.34 11.1 0.1 10.3 9 1 1 10 10 10 5 Leucine Rich Repeat LRR_9 PF14580.1 CBZ23478.1 - 2.1e-14 53.4 5.1 1.3e-05 24.7 0.3 3.7 1 1 2 4 4 4 2 Leucine-rich repeat LRR_7 PF13504.1 CBZ23478.1 - 1.3e-07 30.6 23.0 0.7 10.3 0.1 10.0 10 1 0 10 10 10 3 Leucine rich repeat LRR_6 PF13516.1 CBZ23478.1 - 1.9e-07 30.4 23.6 0.22 11.6 0.1 9.6 5 2 5 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.28 CBZ23479.1 - 9.1e-05 21.9 0.1 1.9 8.8 0.0 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.2 CBZ23479.1 - 0.0055 16.3 0.0 0.28 10.8 0.0 3.1 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Chlorovi_GP_rpt PF06598.6 CBZ23479.1 - 0.012 15.4 1.6 2.8 7.8 0.0 3.1 3 0 0 3 3 3 0 Chlorovirus glycoprotein repeat Histone PF00125.19 CBZ23480.1 - 9.5e-14 51.2 0.6 1.1e-13 51.0 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ23480.1 - 0.00027 20.9 0.1 0.0005 20.0 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CBZ23480.1 - 0.00034 20.4 0.1 0.00058 19.7 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CBZ23480.1 - 0.0014 18.3 0.0 0.0019 17.8 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CBZ23480.1 - 0.0015 18.3 0.0 0.0016 18.2 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF2423 PF10338.4 CBZ23480.1 - 0.089 12.7 2.0 1 9.4 2.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) PCP_red PF08369.5 CBZ23480.1 - 0.12 12.2 0.8 0.35 10.7 0.1 2.1 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit FbpA PF05833.6 CBZ23480.1 - 0.13 10.7 0.0 0.15 10.5 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) LRR_4 PF12799.2 CBZ23481.1 - 4.5e-22 77.2 0.0 0.024 14.2 0.0 8.7 6 3 3 10 10 10 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ23481.1 - 2.9e-10 39.7 10.1 0.072 12.8 0.0 6.7 4 2 5 9 9 9 8 Leucine rich repeat LRR_6 PF13516.1 CBZ23481.1 - 4.7e-05 23.0 23.0 4.8 7.5 0.0 9.4 11 1 0 11 11 11 3 Leucine Rich repeat LRR_9 PF14580.1 CBZ23481.1 - 0.036 13.6 1.1 1 8.8 0.0 3.2 2 1 1 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.28 CBZ23481.1 - 3.4 8.0 24.0 57 4.3 0.1 9.8 10 3 1 11 11 11 0 Leucine Rich Repeat LRR_7 PF13504.1 CBZ23481.1 - 9.7 6.9 27.5 19 6.0 0.1 9.9 12 0 0 12 12 12 0 Leucine rich repeat WD40 PF00400.27 CBZ23482.1 - 2.8e-65 214.0 26.8 3.8e-11 42.4 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBZ23482.1 - 8.4e-05 20.9 11.9 0.062 11.4 0.3 4.8 1 1 2 4 4 4 3 Nucleoporin Nup120/160 PB1 PF00564.19 CBZ23482.1 - 0.01 15.4 0.1 0.036 13.7 0.0 1.9 1 0 0 1 1 1 0 PB1 domain MRP-L46 PF11788.3 CBZ23483.1 - 2.8e-11 44.0 0.0 6.9e-11 42.7 0.0 1.7 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 PUF PF00806.14 CBZ23484.1 - 1.6e-23 80.8 6.6 2.1e-05 23.7 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Glycolytic PF00274.14 CBZ23484.1 - 0.16 10.3 0.0 0.25 9.6 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I CCDC155 PF14662.1 CBZ23485.1 - 0.011 15.2 5.3 0.011 15.2 3.7 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DivIC PF04977.10 CBZ23485.1 - 0.076 12.5 7.0 0.73 9.3 0.1 3.2 3 0 0 3 3 3 0 Septum formation initiator HTH_5 PF01022.15 CBZ23485.1 - 0.088 12.4 2.3 8.2 6.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family DUF2353 PF09789.4 CBZ23485.1 - 0.1 11.8 12.5 0.46 9.7 5.7 2.7 1 1 3 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) Nnf1 PF03980.9 CBZ23485.1 - 0.11 12.4 7.6 5.3 7.0 0.2 3.3 2 1 0 2 2 2 0 Nnf1 bZIP_1 PF00170.16 CBZ23485.1 - 0.16 11.9 9.3 0.22 11.4 0.2 3.2 3 0 0 3 3 3 0 bZIP transcription factor Pox_A_type_inc PF04508.7 CBZ23485.1 - 0.18 11.6 8.6 0.26 11.1 0.3 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF4600 PF15372.1 CBZ23485.1 - 0.54 10.4 6.7 0.37 11.0 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) FlaC_arch PF05377.6 CBZ23485.1 - 1.5 8.7 5.5 16 5.5 0.1 3.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DMPK_coil PF08826.5 CBZ23485.1 - 3.3 7.6 9.7 2.3 8.1 0.1 3.3 3 0 0 3 3 3 0 DMPK coiled coil domain like HisKA PF00512.20 CBZ23485.1 - 4.6 7.3 13.7 2.7 8.0 0.2 4.0 3 2 1 5 5 5 0 His Kinase A (phospho-acceptor) domain APG6 PF04111.7 CBZ23485.1 - 5 6.0 9.9 1.3 8.0 4.5 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 SlyX PF04102.7 CBZ23485.1 - 5.5 7.4 8.2 0.82 10.0 0.6 3.0 3 0 0 3 3 2 0 SlyX DUF972 PF06156.8 CBZ23485.1 - 6.7 7.1 8.3 7.6 6.9 2.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DivIVA PF05103.8 CBZ23485.1 - 7.7 6.5 12.2 0.9 9.5 2.7 2.7 3 0 0 3 3 3 0 DivIVA protein TSC22 PF01166.13 CBZ23485.1 - 8.6 6.4 8.8 7.5 6.6 0.4 3.6 2 1 2 4 4 4 0 TSC-22/dip/bun family Striatin PF08232.7 CBZ23485.1 - 9.9 6.4 12.8 3.7 7.8 2.8 2.7 1 1 2 3 3 3 0 Striatin family Mito_fiss_reg PF05308.6 CBZ23486.1 - 0.12 11.7 1.7 0.24 10.7 1.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator ABC2_membrane PF01061.19 CBZ23487.1 - 7.7e-33 113.4 17.4 7.7e-33 113.4 12.1 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CBZ23487.1 - 1.6e-20 73.8 0.0 2.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ23487.1 - 2.4e-06 27.7 0.0 0.0034 17.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBZ23487.1 - 0.00089 18.5 0.0 0.097 11.8 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBZ23487.1 - 0.0014 18.6 0.1 0.0028 17.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 CBZ23487.1 - 0.0043 16.7 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 NACHT domain FtsK_SpoIIIE PF01580.13 CBZ23487.1 - 0.0089 15.5 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_17 PF13207.1 CBZ23487.1 - 0.0099 16.6 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 CBZ23487.1 - 0.01 15.6 0.3 0.018 14.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_25 PF13481.1 CBZ23487.1 - 0.013 14.9 0.1 0.032 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBZ23487.1 - 0.013 14.6 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 CBZ23487.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBZ23487.1 - 0.022 14.2 0.1 0.051 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 CBZ23487.1 - 0.022 14.4 0.1 0.065 12.9 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 CBZ23487.1 - 0.042 13.3 0.4 0.089 12.3 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CBZ23487.1 - 0.051 13.7 0.2 0.32 11.1 0.0 2.2 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 CBZ23487.1 - 0.1 12.2 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 NTPase cobW PF02492.14 CBZ23487.1 - 0.12 11.8 0.2 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 CBZ23487.1 - 0.19 11.5 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.18 CBZ23487.1 - 0.21 11.5 0.1 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane PF01061.19 CBZ23488.1 - 8.9e-35 119.7 17.4 8.9e-35 119.7 12.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 CBZ23488.1 - 5.5e-21 75.3 0.0 8.1e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ23488.1 - 1.1e-06 28.9 0.0 0.0034 17.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBZ23488.1 - 0.00038 19.7 0.0 0.099 11.8 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBZ23488.1 - 0.0019 18.5 0.0 0.0029 17.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CBZ23488.1 - 0.0031 17.1 0.1 0.0078 15.8 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 CBZ23488.1 - 0.004 17.1 0.1 0.0081 16.1 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CBZ23488.1 - 0.0066 17.2 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 CBZ23488.1 - 0.0072 16.1 0.3 0.012 15.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF87 DUF258 PF03193.11 CBZ23488.1 - 0.0082 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBZ23488.1 - 0.0085 15.5 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CBZ23488.1 - 0.019 14.4 0.1 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 CBZ23488.1 - 0.021 14.3 0.3 0.045 13.2 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBZ23488.1 - 0.024 14.0 0.0 0.054 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 CBZ23488.1 - 0.038 13.7 0.3 0.1 12.3 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 CBZ23488.1 - 0.047 13.8 0.2 0.34 11.0 0.0 2.3 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 CBZ23488.1 - 0.061 13.0 0.1 0.61 9.7 0.0 2.2 2 0 0 2 2 2 0 NTPase cobW PF02492.14 CBZ23488.1 - 0.085 12.3 0.2 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 CBZ23488.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_15 PF13175.1 CBZ23488.1 - 0.33 9.9 0.0 21 4.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain CytochromB561_N PF09786.4 CBZ23490.1 - 0.00079 18.0 0.0 0.0023 16.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome B561, N terminal Pro_isomerase PF00160.16 CBZ23491.1 - 1.9e-48 164.5 0.2 2.2e-48 164.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1768 PF08719.6 CBZ23492.1 - 4e-33 114.3 0.0 4.7e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Proteasome PF00227.21 CBZ23493.1 - 5.6e-30 104.0 0.0 7.8e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit VKOR PF07884.9 CBZ23494.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Vitamin K epoxide reductase family HD PF01966.17 CBZ23495.1 - 6.1e-14 52.0 1.5 7.8e-14 51.7 0.2 1.8 2 0 0 2 2 2 1 HD domain HDOD PF08668.7 CBZ23495.1 - 0.00045 19.5 0.0 0.0008 18.7 0.0 1.3 1 0 0 1 1 1 1 HDOD domain Trm112p PF03966.11 CBZ23496.1 - 2e-07 31.2 0.0 1.3e-06 28.6 0.0 1.9 1 1 0 1 1 1 1 Trm112p-like protein zinc_ribbon_5 PF13719.1 CBZ23496.1 - 0.13 11.8 0.2 0.13 11.8 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBZ23496.1 - 0.2 11.4 0.1 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Kinesin PF00225.18 CBZ23497.1 - 2.6e-71 240.0 0.0 3.4e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain PdxJ PF03740.8 CBZ23497.1 - 0.098 11.7 0.0 0.25 10.4 0.1 1.5 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ FHA PF00498.21 CBZ23500.1 - 1.1e-10 41.4 0.0 1e-08 35.1 0.0 2.5 2 0 0 2 2 2 2 FHA domain DUF4490 PF14892.1 CBZ23501.1 - 0.027 14.1 0.2 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) zf-NADH-PPase PF09297.6 CBZ23501.1 - 0.1 12.1 0.1 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Leu_zip PF15294.1 CBZ23504.1 - 1.8e-09 37.1 11.0 1.1e-05 24.7 1.3 2.2 1 1 1 2 2 2 2 Leucine zipper UPF0449 PF15136.1 CBZ23504.1 - 0.035 14.3 0.7 0.035 14.3 0.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Atg14 PF10186.4 CBZ23504.1 - 0.053 12.4 9.2 0.055 12.4 5.9 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CBZ23504.1 - 0.69 9.4 7.3 1 8.9 5.1 1.4 1 0 0 1 1 1 0 IncA protein HAUS-augmin3 PF14932.1 CBZ23504.1 - 1.1 8.4 11.6 2.8 7.0 0.4 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 ATG16 PF08614.6 CBZ23504.1 - 1.3 8.8 14.5 0.16 11.7 2.4 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FliJ PF02050.11 CBZ23504.1 - 1.5 8.8 18.4 1.2e+02 2.7 11.8 2.7 1 1 1 2 2 2 0 Flagellar FliJ protein Occludin_ELL PF07303.8 CBZ23504.1 - 3.8 8.2 6.7 16 6.3 1.1 2.4 1 1 0 2 2 2 0 Occludin homology domain Mnd1 PF03962.10 CBZ23504.1 - 4.6 6.8 10.0 41 3.7 7.3 1.9 1 1 0 1 1 1 0 Mnd1 family SpaB_C PF14028.1 CBZ23504.1 - 7.2 6.0 13.4 15 5.0 8.7 1.9 1 1 1 2 2 2 0 SpaB C-terminal domain XRN_N PF03159.13 CBZ23505.1 - 5.8e-91 304.0 0.0 9.7e-91 303.3 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus ORC2 PF04084.9 CBZ23505.1 - 0.012 14.4 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 2 Neisseria_TspB PF05616.8 CBZ23505.1 - 3.6 5.8 7.5 8.4 4.6 5.2 1.5 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein FHA PF00498.21 CBZ23507.1 - 0.0025 17.9 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain RNase_H PF00075.19 CBZ23508.1 - 9e-23 81.0 0.3 2.2e-20 73.3 0.2 2.9 1 1 0 1 1 1 1 RNase H zf-MYND PF01753.13 CBZ23509.1 - 2.5e-12 46.4 15.1 2.5e-12 46.4 10.5 1.9 3 0 0 3 3 3 1 MYND finger zf-Mss51 PF13824.1 CBZ23509.1 - 0.5 10.2 6.4 1.2 9.0 4.4 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 BT1 PF03092.11 CBZ23510.1 - 2.9e-145 484.2 9.9 3.4e-145 484.0 6.9 1.0 1 0 0 1 1 1 1 BT1 family TPR_11 PF13414.1 CBZ23512.1 - 9e-06 25.2 7.0 3e-05 23.5 3.7 2.5 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 CBZ23512.1 - 0.00079 19.1 10.0 0.65 10.0 0.6 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ23512.1 - 0.011 16.3 4.5 0.011 16.3 3.1 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ23512.1 - 0.091 13.4 16.8 2.5 8.9 0.6 5.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ23512.1 - 0.33 10.6 4.4 2 8.1 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Sel1 PF08238.7 CBZ23512.1 - 0.36 11.5 7.3 0.52 11.0 0.2 3.0 3 0 0 3 3 3 0 Sel1 repeat Mnd1 PF03962.10 CBZ23512.1 - 4.8 6.8 7.0 8.1 6.0 4.9 1.3 1 0 0 1 1 1 0 Mnd1 family Peptidase_S9 PF00326.16 CBZ23513.1 - 3.3e-34 117.9 0.0 7.1e-34 116.8 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 CBZ23513.1 - 8.6e-26 90.4 0.0 1.8e-25 89.3 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain 3Beta_HSD PF01073.14 CBZ23514.1 - 4.2e-28 97.8 0.0 5.2e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CBZ23514.1 - 6.4e-20 71.6 0.0 8.4e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CBZ23514.1 - 1.6e-10 40.3 0.0 2.2e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CBZ23514.1 - 1.1e-07 32.0 0.0 1.5e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CBZ23514.1 - 1.6e-05 23.9 0.0 2.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CBZ23514.1 - 0.00059 18.8 0.0 0.00092 18.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CBZ23514.1 - 0.0012 18.1 0.0 0.0018 17.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Gln-synt_C PF00120.19 CBZ23516.1 - 5e-47 160.2 0.0 6.4e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CBZ23516.1 - 2.6e-16 58.9 0.0 5e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain zf-CCCH PF00642.19 CBZ23517.1 - 6.9e-07 28.7 1.5 1.5e-06 27.7 1.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ23517.1 - 0.011 15.7 1.9 0.011 15.7 1.3 2.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_L19e PF01280.15 CBZ23520.1 - 2.2e-59 199.4 12.9 2.2e-59 199.4 9.0 2.1 1 1 1 2 2 2 1 Ribosomal protein L19e Menin PF05053.8 CBZ23520.1 - 0.19 9.8 5.9 0.27 9.3 4.1 1.2 1 0 0 1 1 1 0 Menin Opi1 PF08618.5 CBZ23520.1 - 0.56 9.0 10.5 0.76 8.6 7.3 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 APG6 PF04111.7 CBZ23520.1 - 1.8 7.5 8.0 2.4 7.1 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 OrfB_Zn_ribbon PF07282.6 CBZ23521.1 - 0.07 12.7 0.5 0.17 11.5 0.3 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L19e PF01280.15 CBZ23522.1 - 2.2e-59 199.4 12.9 2.2e-59 199.4 9.0 2.1 1 1 1 2 2 2 1 Ribosomal protein L19e Menin PF05053.8 CBZ23522.1 - 0.19 9.8 5.9 0.27 9.3 4.1 1.2 1 0 0 1 1 1 0 Menin Opi1 PF08618.5 CBZ23522.1 - 0.56 9.0 10.5 0.76 8.6 7.3 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 APG6 PF04111.7 CBZ23522.1 - 1.8 7.5 8.0 2.4 7.1 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinesin PF00225.18 CBZ23524.1 - 2.1e-10 39.8 5.8 0.00013 20.8 0.0 3.1 3 0 0 3 3 3 2 Kinesin motor domain AAA_13 PF13166.1 CBZ23524.1 - 0.011 14.2 7.0 0.016 13.7 4.9 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBZ23524.1 - 0.029 14.6 1.1 0.049 13.9 0.7 1.3 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.6 CBZ23524.1 - 0.074 12.9 2.1 0.64 9.9 0.0 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 CBZ23524.1 - 0.083 12.7 13.5 0.049 13.4 6.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Effector_1 PF04518.7 CBZ23524.1 - 0.4 9.6 14.2 0.056 12.4 5.1 2.1 1 1 1 2 2 2 0 Effector from type III secretion system Mnd1 PF03962.10 CBZ23524.1 - 0.87 9.2 24.9 1.1 8.8 5.7 2.6 1 1 2 3 3 3 0 Mnd1 family DUF1664 PF07889.7 CBZ23524.1 - 1.9 8.3 11.6 0.17 11.6 2.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2730 PF10805.3 CBZ23524.1 - 5.1 6.8 8.1 1.6 8.4 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TPR_11 PF13414.1 CBZ23525.1 - 1.5e-06 27.7 1.9 9.6e-06 25.1 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 CBZ23525.1 - 1e-05 25.3 0.3 0.00044 20.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ23525.1 - 0.001 18.6 2.6 0.028 14.0 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ23525.1 - 0.0019 18.0 3.8 0.011 15.6 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ23525.1 - 0.005 16.5 0.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ23525.1 - 0.0091 15.8 0.0 0.055 13.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat HrpF PF06266.7 CBZ23525.1 - 0.11 12.5 1.2 0.89 9.7 0.0 2.9 2 1 0 2 2 2 0 HrpF protein NAD_kinase PF01513.16 CBZ23527.1 - 1.8e-13 49.9 0.0 3.6e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase Cnd2 PF05786.9 CBZ23528.1 - 2.8e-21 75.7 10.2 3.8e-13 48.8 0.4 3.1 3 0 0 3 3 3 2 Condensin complex subunit 2 DUF3870 PF12986.2 CBZ23528.1 - 0.18 12.0 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) SpoU_methylase PF00588.14 CBZ23531.1 - 8.9e-16 58.0 0.0 1.2e-09 38.1 0.0 3.1 3 0 0 3 3 3 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 CBZ23531.1 - 6.3e-05 23.0 0.0 0.00049 20.2 0.0 2.2 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding K_channel_TID PF07941.6 CBZ23531.1 - 0.021 15.0 0.1 0.021 15.0 0.1 3.1 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain U-box PF04564.10 CBZ23532.1 - 3.5e-12 46.1 0.0 8e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 U-box domain LRR_4 PF12799.2 CBZ23533.1 - 2.5e-16 58.8 1.0 0.044 13.4 0.0 8.6 8 1 0 8 8 8 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBZ23533.1 - 1.2e-05 24.8 18.2 4.9 7.5 0.0 10.0 12 0 0 12 12 12 3 Leucine Rich repeat LRR_8 PF13855.1 CBZ23533.1 - 0.00024 20.7 9.4 19 5.0 0.6 7.3 7 1 0 7 7 7 3 Leucine rich repeat Maf_N PF08383.6 CBZ23534.1 - 0.13 11.8 0.2 0.13 11.8 0.1 2.4 2 0 0 2 2 2 0 Maf N-terminal region dUTPase_2 PF08761.6 CBZ23537.1 - 4.3e-39 134.2 0.0 6.2e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 dUTPase Mvb12 PF09452.5 CBZ23537.1 - 0.092 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 Ribosomal_L23 PF00276.15 CBZ23538.1 - 8.1e-21 73.7 2.7 8.1e-21 73.7 1.9 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 CBZ23538.1 - 9.2e-12 44.8 13.6 9.2e-12 44.8 9.4 2.2 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Late_protein_L2 PF00513.13 CBZ23538.1 - 0.00021 20.2 2.0 0.00026 20.0 1.4 1.0 1 0 0 1 1 1 1 Late Protein L2 TusA PF01206.12 CBZ23538.1 - 0.023 14.3 1.0 0.036 13.6 0.1 1.8 2 0 0 2 2 2 0 Sulfurtransferase TusA P2 PF07194.6 CBZ23538.1 - 0.038 13.8 0.4 0.071 12.9 0.3 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain Pyridox_oxase_2 PF12766.2 CBZ23538.1 - 3.7 7.9 5.4 11 6.3 3.7 2.0 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Ribosomal_L23 PF00276.15 CBZ23539.1 - 8.1e-21 73.7 2.7 8.1e-21 73.7 1.9 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 CBZ23539.1 - 9.2e-12 44.8 13.6 9.2e-12 44.8 9.4 2.2 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Late_protein_L2 PF00513.13 CBZ23539.1 - 0.00021 20.2 2.0 0.00026 20.0 1.4 1.0 1 0 0 1 1 1 1 Late Protein L2 TusA PF01206.12 CBZ23539.1 - 0.023 14.3 1.0 0.036 13.6 0.1 1.8 2 0 0 2 2 2 0 Sulfurtransferase TusA P2 PF07194.6 CBZ23539.1 - 0.038 13.8 0.4 0.071 12.9 0.3 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain Pyridox_oxase_2 PF12766.2 CBZ23539.1 - 3.7 7.9 5.4 11 6.3 3.7 2.0 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase PHD PF00628.24 CBZ23541.1 - 0.00022 20.8 0.9 0.00022 20.8 0.6 1.9 2 0 0 2 2 2 1 PHD-finger DUF4206 PF13901.1 CBZ23541.1 - 0.17 11.3 0.6 0.3 10.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) zf-RING_2 PF13639.1 CBZ23541.1 - 2.5 7.9 7.4 1.1 9.1 1.9 2.3 2 0 0 2 2 2 0 Ring finger domain Pro_CA PF00484.14 CBZ23542.1 - 3.6e-40 137.4 1.4 1.5e-39 135.4 1.0 1.9 1 1 0 1 1 1 1 Carbonic anhydrase Rsc14 PF08586.5 CBZ23542.1 - 0.018 15.5 0.0 0.58 10.6 0.0 2.3 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DUF89 PF01937.14 CBZ23543.1 - 3.8e-40 137.7 0.1 1.2e-21 76.9 0.0 4.5 4 0 0 4 4 4 4 Protein of unknown function DUF89 Put_Phosphatase PF06888.7 CBZ23543.1 - 4.6e-33 114.3 0.9 8.3e-15 54.5 0.0 3.4 3 0 0 3 3 3 3 Putative Phosphatase HAD PF12710.2 CBZ23543.1 - 0.033 14.3 0.1 0.49 10.5 0.1 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 CBZ23545.1 - 1.2e-46 158.9 0.0 3.3e-46 157.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23545.1 - 5.7e-31 107.5 0.0 1.6e-22 79.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 CBZ23545.1 - 3e-09 36.8 0.0 5.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain PAS_9 PF13426.1 CBZ23545.1 - 0.00011 22.4 0.0 0.87 9.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain Kinase-like PF14531.1 CBZ23545.1 - 0.00082 18.4 0.1 0.0019 17.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like PAS PF00989.19 CBZ23545.1 - 0.0035 17.1 0.0 0.27 11.0 0.0 2.7 2 0 0 2 2 2 1 PAS fold Kdo PF06293.9 CBZ23545.1 - 0.22 10.5 0.0 0.43 9.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBZ23545.1 - 0.49 9.7 0.0 0.79 9.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Prenyltrans_1 PF13243.1 CBZ23546.1 - 1.4e-20 73.3 1.9 1.1e-05 25.4 0.0 4.8 4 1 1 5 5 5 3 Prenyltransferase-like Prenyltrans_2 PF13249.1 CBZ23546.1 - 1.3e-19 70.6 0.6 3.1e-10 40.4 0.1 5.0 3 1 2 5 5 5 4 Prenyltransferase-like Prenyltrans PF00432.16 CBZ23546.1 - 6.5e-19 67.1 11.0 3.8e-08 32.7 0.0 5.6 5 1 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.5 CBZ23546.1 - 6.2e-06 25.5 0.1 0.19 10.8 0.0 4.0 3 1 2 5 5 5 3 Pectic acid lyase Cmc1 PF08583.5 CBZ23549.1 - 0.00051 19.7 3.8 0.00087 19.0 2.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 CBZ23549.1 - 0.0015 17.8 3.8 0.0027 17.0 2.6 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 CBZ23549.1 - 0.38 10.7 4.7 0.62 10.0 3.3 1.4 1 0 0 1 1 1 0 CHCH domain Ctf8 PF09696.5 CBZ23550.1 - 6.4e-06 25.9 0.0 0.031 14.0 0.0 3.2 3 0 0 3 3 3 3 Ctf8 zf-CCHC_2 PF13696.1 CBZ23551.1 - 0.14 11.6 7.6 4 7.0 2.7 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-ribbon_3 PF13248.1 CBZ23551.1 - 3.5 6.9 7.1 6.5 6.1 1.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Ank_5 PF13857.1 CBZ23552.1 - 1.5e-10 40.9 2.6 0.00099 19.2 0.1 3.9 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBZ23552.1 - 2.4e-09 37.3 0.0 1.2e-08 35.1 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ23552.1 - 1.7e-08 33.8 0.1 0.0039 16.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat C2 PF00168.25 CBZ23552.1 - 1.9e-08 34.0 0.0 3.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain Ank_4 PF13637.1 CBZ23552.1 - 4.3e-07 30.2 0.4 0.0023 18.3 0.0 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ23552.1 - 3.4e-05 23.6 0.0 0.14 12.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat YEATS PF03366.11 CBZ23554.1 - 1.2e-15 56.9 0.0 4.3e-15 55.2 0.0 1.8 1 1 0 1 1 1 1 YEATS family Daxx PF03344.10 CBZ23554.1 - 0.74 8.2 10.4 1.7 7.0 7.2 1.5 1 0 0 1 1 1 0 Daxx Family PALP PF00291.20 CBZ23555.1 - 1.5e-56 191.8 0.4 1.7e-56 191.6 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HlyIII PF03006.15 CBZ23557.1 - 1.5e-21 76.8 0.0 1.1e-13 51.0 0.0 2.5 2 1 0 2 2 2 2 Haemolysin-III related RRM_1 PF00076.17 CBZ23559.1 - 1.9e-26 91.4 0.0 8.2e-14 51.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23559.1 - 4.8e-20 71.3 0.0 7.2e-09 35.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ23559.1 - 4.6e-07 29.5 0.0 0.033 14.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3951 PF13131.1 CBZ23559.1 - 0.1 12.3 0.1 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) RNA_bind PF08675.6 CBZ23559.1 - 0.29 11.1 0.0 16 5.5 0.0 2.8 3 0 0 3 3 3 0 RNA binding domain Glyoxalase PF00903.20 CBZ23563.1 - 0.012 15.5 0.0 0.035 14.0 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3166 PF11365.3 CBZ23563.1 - 0.024 15.0 8.1 0.49 10.8 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3166) Phage_tail_T PF06223.7 CBZ23563.1 - 0.042 14.2 1.8 0.15 12.4 0.1 2.2 2 0 0 2 2 2 0 Minor tail protein T Cwf_Cwc_15 PF04889.7 CBZ23563.1 - 0.043 13.5 5.5 0.072 12.7 3.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyoxalase_2 PF12681.2 CBZ23563.1 - 0.074 13.6 0.2 0.26 11.9 0.0 2.1 2 1 0 2 2 2 0 Glyoxalase-like domain CENP-Q PF13094.1 CBZ23563.1 - 0.088 12.8 7.5 0.45 10.5 0.7 2.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit RmuC PF02646.11 CBZ23563.1 - 0.1 11.4 2.5 0.083 11.7 0.1 1.9 3 0 0 3 3 3 0 RmuC family ADIP PF11559.3 CBZ23563.1 - 0.3 10.9 11.4 3.1 7.7 2.7 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 CBZ23563.1 - 0.81 8.8 4.8 3.8 6.6 0.1 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding SNARE PF05739.14 CBZ23563.1 - 0.85 9.3 10.3 0.13 11.9 3.2 2.3 2 0 0 2 2 2 0 SNARE domain YlqD PF11068.3 CBZ23563.1 - 2.9 7.9 6.6 2 8.4 0.2 2.7 3 0 0 3 3 3 0 YlqD protein COG2 PF06148.6 CBZ23563.1 - 4.2 7.2 7.3 0.5 10.2 0.5 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 CBZ23563.1 - 7.6 5.3 11.8 0.33 9.8 3.2 2.2 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 CBZ23563.1 - 7.7 6.4 16.6 0.56 10.1 1.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) LNS2 PF08235.8 CBZ23564.1 - 2.6e-53 179.7 0.0 4e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CBZ23564.1 - 1.7e-17 63.0 0.0 3.6e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 CBZ23564.1 - 0.041 13.2 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DHquinase_II PF01220.14 CBZ23564.1 - 0.21 10.9 0.0 0.44 9.8 0.0 1.4 1 0 0 1 1 1 0 Dehydroquinase class II EF-hand_1 PF00036.27 CBZ23566.1 - 0.043 13.1 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 CBZ23566.1 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 CBZ23566.1 - 0.46 10.4 0.0 1.2 9.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain NARP1 PF12569.3 CBZ23566.1 - 0.71 8.5 4.8 1.2 7.7 3.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GBP_C PF02841.9 CBZ23566.1 - 8.6 5.4 9.7 17 4.4 6.7 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Thymidylat_synt PF00303.14 CBZ23567.1 - 5e-109 363.4 0.0 6.4e-109 363.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.14 CBZ23567.1 - 3.4e-25 88.4 0.0 3e-24 85.4 0.0 2.4 1 1 0 1 1 1 1 Dihydrofolate reductase Spo12 PF05032.7 CBZ23567.1 - 0.089 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Spo12 family Methyltransf_18 PF12847.2 CBZ23568.1 - 2.9e-10 40.6 0.0 6e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBZ23568.1 - 1e-08 34.6 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CBZ23568.1 - 7.9e-06 25.3 0.0 2.2e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 CBZ23568.1 - 9.2e-06 25.2 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 CBZ23568.1 - 4.2e-05 23.5 0.0 0.0001 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CBZ23568.1 - 8.6e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.11 CBZ23568.1 - 0.0002 21.0 0.0 0.00033 20.3 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 CBZ23568.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 CBZ23568.1 - 0.0026 16.8 0.0 0.004 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 CBZ23568.1 - 0.0031 17.0 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 CBZ23568.1 - 0.0091 14.9 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 CBZ23568.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ23568.1 - 0.014 15.8 0.1 0.081 13.4 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain CMAS PF02353.15 CBZ23568.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CBZ23568.1 - 0.032 14.5 0.0 0.073 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 CBZ23568.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Acyl-CoA_dh_1 PF00441.19 CBZ23569.1 - 4.5e-49 166.4 3.2 6.9e-49 165.8 2.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBZ23569.1 - 3.4e-27 95.2 0.3 9.2e-27 93.8 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBZ23569.1 - 7.9e-22 76.5 1.0 2.3e-21 75.0 0.3 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBZ23569.1 - 8.1e-21 74.6 0.9 1.3e-20 73.9 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 CBZ23569.1 - 7.3e-05 22.2 0.3 0.00033 20.1 0.2 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PcrB PF01884.12 CBZ23569.1 - 0.089 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 PcrB family PP2C PF00481.16 CBZ23571.1 - 3.5e-26 92.1 0.1 9e-17 61.2 0.0 3.5 4 0 0 4 4 4 3 Protein phosphatase 2C SpoIIE PF07228.7 CBZ23571.1 - 0.0081 15.8 0.0 0.03 14.0 0.0 2.0 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PTH2 PF01981.11 CBZ23572.1 - 2.4e-48 162.6 0.2 3.4e-48 162.1 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Oxidored_FMN PF00724.15 CBZ23574.1 - 1.4e-47 162.3 0.0 1.8e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.9 CBZ23574.1 - 3.6e-10 40.0 0.0 1.1e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ23574.1 - 6.1e-10 38.9 0.0 2.1e-09 37.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CBZ23574.1 - 4.2e-08 32.4 0.0 9.3e-08 31.3 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CBZ23574.1 - 8e-08 32.5 0.3 0.00043 20.4 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBZ23574.1 - 9.6e-08 31.2 0.0 1.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CBZ23574.1 - 1.1e-06 28.9 0.4 0.0004 20.7 0.4 3.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBZ23574.1 - 3.1e-06 25.9 1.6 4.6e-06 25.3 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 CBZ23574.1 - 3.3e-06 26.4 1.7 1.7e-05 24.1 1.2 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CBZ23574.1 - 0.0004 19.5 0.1 0.00091 18.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 CBZ23574.1 - 0.001 18.0 0.3 0.0015 17.4 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 CBZ23574.1 - 0.0032 16.6 0.0 0.005 15.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 CBZ23574.1 - 0.0092 15.0 0.1 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 CBZ23574.1 - 0.01 15.2 0.5 0.029 13.8 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 CBZ23574.1 - 0.011 15.3 0.1 0.026 14.1 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 CBZ23574.1 - 0.017 14.8 0.1 0.039 13.6 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 CBZ23574.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 CBZ23574.1 - 0.068 13.4 0.1 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 CBZ23574.1 - 0.084 12.6 0.1 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding FMO-like PF00743.14 CBZ23574.1 - 0.09 10.9 0.1 1.8 6.6 0.0 2.1 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like ThiF PF00899.16 CBZ23574.1 - 0.097 12.4 0.1 0.9 9.3 0.0 2.6 3 0 0 3 3 3 0 ThiF family NAD_binding_10 PF13460.1 CBZ23574.1 - 0.17 11.8 2.9 0.52 10.2 0.3 2.7 3 0 0 3 3 3 0 NADH(P)-binding TLD PF07534.11 CBZ23575.1 - 9.3e-09 35.3 0.0 6.8e-05 22.8 0.0 3.2 3 0 0 3 3 3 3 TLD SIS PF01380.17 CBZ23576.1 - 3.9e-50 168.8 0.9 1.4e-25 89.3 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 CBZ23576.1 - 7.1e-17 61.6 0.0 4.3e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CBZ23576.1 - 8.1e-17 60.9 0.4 7.9e-12 44.5 0.1 2.4 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 CBZ23576.1 - 1.4e-10 40.9 0.0 3.7e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain SIS_2 PF13580.1 CBZ23576.1 - 7.6e-05 22.4 0.1 0.016 14.9 0.0 2.7 3 0 0 3 3 3 1 SIS domain GATase_4 PF13230.1 CBZ23576.1 - 0.0001 21.0 0.1 0.0002 20.1 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II LuxQ-periplasm PF09308.5 CBZ23576.1 - 0.024 13.9 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 LuxQ, periplasmic DUF2529 PF10740.4 CBZ23576.1 - 0.084 12.2 0.1 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2529) Mob1_phocein PF03637.12 CBZ23577.1 - 6e-64 214.9 0.3 7e-64 214.6 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF3883 PF13020.1 CBZ23578.1 - 1.1e-15 57.1 0.0 2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) LRR_8 PF13855.1 CBZ23579.1 - 3.2e-25 87.6 8.2 2.2e-06 27.3 0.3 4.7 4 0 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.2 CBZ23579.1 - 2.9e-24 84.1 8.1 1.3e-06 27.8 0.0 8.0 3 3 5 9 9 9 6 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBZ23579.1 - 4.9e-14 50.0 4.7 3.1 8.3 0.0 11.4 12 0 0 12 12 12 2 Leucine rich repeat LRR_1 PF00560.28 CBZ23579.1 - 1.9e-09 36.2 20.2 0.59 10.3 0.1 10.8 10 2 0 10 10 10 3 Leucine Rich Repeat LRR_6 PF13516.1 CBZ23579.1 - 5e-05 22.9 12.4 46 4.5 0.0 9.0 11 0 0 11 11 11 0 Leucine Rich repeat DUF1399 PF07173.7 CBZ23579.1 - 0.00069 19.9 5.6 0.05 13.8 0.1 3.6 3 1 1 4 4 4 2 Protein of unknown function (DUF1399) LRR_9 PF14580.1 CBZ23579.1 - 0.0036 16.8 1.0 4.9 6.6 0.1 3.8 3 1 1 4 4 4 1 Leucine-rich repeat DUF3024 PF11225.3 CBZ23579.1 - 0.069 13.0 0.6 0.19 11.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) WD40 PF00400.27 CBZ23580.1 - 0.00011 21.9 0.3 0.083 12.8 0.0 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Claudin_2 PF13903.1 CBZ23581.1 - 0.067 12.8 4.7 0.29 10.8 0.5 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SET PF00856.23 CBZ23582.1 - 2.4e-12 47.4 0.0 4e-11 43.4 0.0 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 CBZ23582.1 - 9.9e-05 22.1 9.8 9.9e-05 22.1 6.8 2.9 3 1 0 3 3 3 1 MYND finger G-patch PF01585.18 CBZ23584.1 - 1.1e-12 47.5 1.1 1.8e-12 46.8 0.8 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBZ23584.1 - 5.5e-08 32.5 0.6 1.3e-07 31.3 0.4 1.6 1 0 0 1 1 1 1 DExH-box splicing factor binding site Adeno_E1B_55K_N PF04623.7 CBZ23584.1 - 7.1 7.2 7.5 0.99 9.9 0.3 2.5 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus Kinesin PF00225.18 CBZ23585.1 - 3.4e-63 213.3 0.0 8.5e-63 212.0 0.0 1.6 1 1 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 CBZ23585.1 - 0.094 12.8 0.4 0.47 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CBZ23585.1 - 0.14 12.0 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 Thioredoxin PF00085.15 CBZ23587.1 - 2.1e-27 94.8 0.0 2.5e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 CBZ23587.1 - 8.2e-08 32.1 0.0 1.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBZ23587.1 - 4e-07 30.2 0.1 4.1e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ23587.1 - 0.00015 21.8 0.1 0.0034 17.4 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_5 PF13743.1 CBZ23587.1 - 0.0059 16.1 0.1 0.42 10.1 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin LPAM_1 PF08139.7 CBZ23587.1 - 0.011 15.9 3.3 0.023 14.9 2.3 1.6 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site TraF PF13728.1 CBZ23587.1 - 0.053 13.0 0.0 0.086 12.3 0.0 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein LPAM_2 PF13627.1 CBZ23587.1 - 2.2 8.0 5.3 3.3 7.5 3.7 1.3 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site 2OG-FeII_Oxy_2 PF13532.1 CBZ23588.1 - 2.4e-08 34.0 0.0 6e-08 32.7 0.0 1.5 1 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DeoC PF01791.4 CBZ23589.1 - 5.2e-45 153.5 7.2 6.2e-45 153.3 5.0 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase PilX_N PF14341.1 CBZ23589.1 - 0.051 13.2 0.0 0.18 11.4 0.0 2.0 1 0 0 1 1 1 0 PilX N-terminal SNase PF00565.12 CBZ23590.1 - 1.4e-18 67.0 0.0 2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Med9 PF07544.8 CBZ23591.1 - 0.039 13.6 16.5 0.43 10.3 2.2 4.3 3 2 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Reo_sigmaC PF04582.7 CBZ23591.1 - 0.88 8.6 17.7 0.64 9.1 0.3 3.6 2 1 1 4 4 4 0 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 CBZ23591.1 - 6 4.4 49.0 0.006 14.3 4.2 2.7 2 1 0 2 2 2 0 Myosin tail ATG16 PF08614.6 CBZ23591.1 - 8.7 6.1 51.9 1.4 8.6 2.6 4.7 2 2 3 5 5 5 0 Autophagy protein 16 (ATG16) TraC PF07820.7 CBZ23592.1 - 0.57 10.4 0.0 0.57 10.4 0.0 2.3 3 0 0 3 3 3 0 TraC-like protein PIG-X PF08320.7 CBZ23594.1 - 0.003 16.8 0.0 0.071 12.3 0.0 2.6 2 1 0 2 2 2 1 PIG-X / PBN1 WD40 PF00400.27 CBZ23595.1 - 6.7e-07 28.9 5.3 5.8e-06 25.9 0.1 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat DisA_N PF02457.11 CBZ23596.1 - 0.11 11.6 0.6 0.3 10.2 0.4 1.7 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding DUF4379 PF14311.1 CBZ23597.1 - 1.7e-27 94.9 24.4 3.4e-10 39.5 0.2 4.8 4 0 0 4 4 4 3 Domain of unknown function (DUF4379) SprT-like PF10263.4 CBZ23597.1 - 0.00036 20.2 7.1 0.32 10.6 0.1 3.5 3 0 0 3 3 3 2 SprT-like family HypA PF01155.14 CBZ23597.1 - 0.16 11.6 19.1 0.58 9.8 0.0 4.5 3 2 0 4 4 4 0 Hydrogenase expression/synthesis hypA family NTF2 PF02136.15 CBZ23599.1 - 4.3e-15 56.1 0.0 4.9e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Pkinase PF00069.20 CBZ23600.1 - 2.3e-59 200.6 0.0 9.9e-38 129.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23600.1 - 2e-32 112.3 0.0 2.4e-23 82.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBZ23600.1 - 5.5e-05 23.0 0.0 0.12 12.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ23600.1 - 0.00032 19.7 0.0 0.00074 18.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBZ23600.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 CBZ23600.1 - 0.074 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Thioredoxin PF00085.15 CBZ23601.1 - 1e-10 41.2 0.0 1.3e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 CBZ23601.1 - 0.071 12.9 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ23601.1 - 0.13 12.3 0.5 1.6 8.9 0.2 2.0 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.1 CBZ23601.1 - 0.13 12.4 0.1 0.24 11.6 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DUF1637 PF07847.7 CBZ23605.1 - 6e-49 166.1 0.0 7.3e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) CDO_I PF05995.7 CBZ23605.1 - 0.033 13.3 0.0 1.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Cysteine dioxygenase type I Cupin_2 PF07883.6 CBZ23605.1 - 0.078 12.4 0.0 2.9 7.4 0.0 2.9 3 0 0 3 3 3 0 Cupin domain FAD_binding_3 PF01494.14 CBZ23606.1 - 1.5e-09 37.4 0.0 6.6e-09 35.2 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 CBZ23606.1 - 0.019 13.8 0.0 0.034 12.9 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Hpt PF01627.18 CBZ23606.1 - 0.053 13.5 0.4 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Hpt domain EnY2 PF10163.4 CBZ23607.1 - 6.8e-05 22.7 0.0 8.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Transcription factor e(y)2 Phage_head_chap PF11113.3 CBZ23607.1 - 0.019 14.8 0.1 0.84 9.5 0.0 2.3 2 0 0 2 2 2 0 Head assembly gene product DUF3899 PF13038.1 CBZ23608.1 - 0.0052 16.9 6.0 0.27 11.3 0.0 3.3 2 1 1 3 3 3 1 Domain of unknown function (DUF3899) WTF PF03303.8 CBZ23608.1 - 0.11 11.9 2.5 0.2 11.0 1.7 1.5 1 0 0 1 1 1 0 WTF protein RE_SinI PF09570.5 CBZ23608.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 SinI restriction endonuclease DUF4191 PF13829.1 CBZ23608.1 - 0.28 10.2 0.0 0.28 10.2 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) DFF-C PF09033.5 CBZ23608.1 - 0.63 9.8 3.3 1.1 9.0 2.3 1.3 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain V_ATPase_I PF01496.14 CBZ23608.1 - 0.92 7.2 8.2 0.021 12.6 0.4 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family BT1 PF03092.11 CBZ23609.1 - 2.2e-142 474.7 9.3 2.6e-142 474.5 6.4 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 CBZ23609.1 - 0.023 13.4 42.4 0.04 12.6 5.9 3.4 1 1 1 2 2 2 0 Major Facilitator Superfamily p53-inducible11 PF14936.1 CBZ23609.1 - 0.06 13.2 0.5 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 Coprogen_oxidas PF01218.13 CBZ23610.1 - 8.8e-142 470.9 0.1 9.9e-142 470.7 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Flavodoxin_5 PF12724.2 CBZ23611.1 - 1.3e-47 161.3 0.1 1.7e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.2 CBZ23611.1 - 0.00043 19.7 0.1 0.00056 19.3 0.1 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_1 PF00258.20 CBZ23611.1 - 0.013 15.4 0.1 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin Cyt-b5 PF00173.23 CBZ23612.1 - 9.7e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1583 PF07622.6 CBZ23612.1 - 0.027 12.9 0.1 0.038 12.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1583) ThiF PF00899.16 CBZ23613.1 - 1.6e-29 102.4 0.0 3.1e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CBZ23613.1 - 6.3e-06 26.3 0.1 0.00085 19.4 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 CBZ23613.1 - 0.0028 17.6 4.1 1.1 9.1 0.1 2.5 2 0 0 2 2 2 2 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 CBZ23613.1 - 0.031 13.4 0.0 7.1 5.7 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Isy1 PF06246.7 CBZ23614.1 - 3.7e-11 42.9 8.7 4.8e-09 35.9 6.0 2.8 1 1 0 1 1 1 1 Isy1-like splicing family DOT1 PF08123.8 CBZ23615.1 - 1.2e-21 76.9 0.0 2.1e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 CBZ23615.1 - 2.1e-07 31.5 0.0 3.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ23615.1 - 4.3e-06 26.3 0.0 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ23615.1 - 7.4e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ23615.1 - 0.00031 21.0 0.0 0.00051 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CBZ23615.1 - 0.0021 17.7 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ23615.1 - 0.0037 17.7 0.0 0.007 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBZ23615.1 - 0.0072 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CBZ23615.1 - 0.031 14.7 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ23615.1 - 0.046 13.4 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.8 CBZ23615.1 - 0.056 13.5 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MTS PF05175.9 CBZ23615.1 - 0.097 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 CBZ23615.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Adaptin_N PF01602.15 CBZ23618.1 - 3.1e-85 286.5 9.8 3.9e-85 286.1 6.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CBZ23618.1 - 0.00036 20.7 0.1 0.19 12.0 0.0 3.7 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 CBZ23618.1 - 0.095 12.8 0.1 1.4 9.1 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat Cytochrom_C1 PF02167.10 CBZ23619.1 - 5.3e-66 222.4 0.0 6.5e-66 222.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family S-methyl_trans PF02574.11 CBZ23622.1 - 7.1e-94 314.5 0.0 1.3e-93 313.6 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.12 CBZ23622.1 - 8.9e-65 217.8 0.5 2.8e-64 216.1 0.1 2.0 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 CBZ23622.1 - 1.1e-35 122.8 0.0 4.7e-35 120.8 0.0 2.1 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.12 CBZ23622.1 - 5.5e-22 77.5 0.1 3.3e-21 75.0 0.0 2.5 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.14 CBZ23622.1 - 2.7e-21 75.6 1.3 1e-20 73.7 0.4 2.4 2 0 0 2 2 2 1 B12 binding domain OKR_DC_1_N PF03709.10 CBZ23622.1 - 0.061 13.3 0.0 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Peptidase_M16_C PF05193.16 CBZ23623.1 - 6.2e-26 91.1 0.0 2.7e-14 53.2 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain M16C_assoc PF08367.6 CBZ23623.1 - 3e-21 75.4 0.0 5.3e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16 PF00675.15 CBZ23623.1 - 1.7e-15 57.1 2.7 4.2e-12 46.0 0.0 2.9 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) DUF1542 PF07564.6 CBZ23623.1 - 0.13 12.2 5.4 0.55 10.2 1.1 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Shugoshin_C PF07557.6 CBZ23623.1 - 0.18 11.2 0.1 0.18 11.2 0.0 2.3 2 0 0 2 2 2 0 Shugoshin C terminus EF-hand_1 PF00036.27 CBZ23624.1 - 1e-24 83.8 3.8 6.2e-07 28.2 0.0 5.0 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CBZ23624.1 - 2.4e-21 75.0 0.2 1.5e-06 27.7 0.0 4.5 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CBZ23624.1 - 2.4e-21 73.6 0.4 0.00015 21.3 0.0 5.6 6 0 0 6 6 6 4 EF-hand domain EF-hand_7 PF13499.1 CBZ23624.1 - 2.7e-21 75.4 0.0 5.5e-08 32.8 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBZ23624.1 - 2.1e-15 55.2 2.9 9.7e-06 24.6 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CBZ23624.1 - 0.0022 17.7 0.0 3.4 7.4 0.0 3.2 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBZ23624.1 - 0.052 13.5 0.0 2.8 8.0 0.0 2.9 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CBZ23624.1 - 0.15 11.9 0.2 7.6 6.5 0.0 3.1 3 1 0 3 3 3 0 EF-hand domain Sec7 PF01369.15 CBZ23625.1 - 7.3e-36 123.6 0.0 1.5e-35 122.6 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain tRNA_Me_trans PF03054.11 CBZ23626.1 - 7.4e-42 143.1 0.0 2.3e-28 98.7 0.0 4.5 3 1 0 3 3 3 3 tRNA methyl transferase Asn_synthase PF00733.16 CBZ23626.1 - 0.014 14.9 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.12 CBZ23626.1 - 0.02 13.8 0.1 0.035 13.0 0.1 1.3 1 0 0 1 1 1 0 NAD synthase DUF1751 PF08551.5 CBZ23627.1 - 0.01 16.1 0.4 0.033 14.5 0.1 2.0 1 1 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Med3 PF11593.3 CBZ23627.1 - 0.52 9.4 7.1 0.78 8.9 4.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF747 PF05346.6 CBZ23628.1 - 2.3e-60 204.4 2.6 3.1e-60 203.9 1.8 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Pkinase PF00069.20 CBZ23629.1 - 4.7e-49 166.8 0.0 8.3e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23629.1 - 1.5e-31 109.3 0.0 2.9e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23629.1 - 7.1e-07 28.4 0.0 1.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 CBZ23629.1 - 0.3 9.8 0.0 0.48 9.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 CBZ23630.1 - 7e-51 172.8 0.0 7e-31 107.3 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23630.1 - 1.2e-34 119.5 0.0 3.3e-20 72.2 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23630.1 - 0.00084 18.3 0.0 0.21 10.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like CinA PF02464.12 CBZ23630.1 - 0.018 14.4 0.1 0.044 13.2 0.1 1.5 1 0 0 1 1 1 0 Competence-damaged protein Kdo PF06293.9 CBZ23630.1 - 0.083 11.9 3.0 0.58 9.1 0.2 2.6 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTPA PF03095.10 CBZ23632.1 - 3.1e-104 348.3 0.0 3.7e-104 348.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF3329 PF11808.3 CBZ23632.1 - 0.064 13.3 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) PLDc_2 PF13091.1 CBZ23633.1 - 5e-09 35.9 0.0 6.7e-05 22.6 0.0 3.3 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 CBZ23633.1 - 4.3e-06 26.3 0.8 2.5e-05 23.8 0.0 2.6 3 0 0 3 3 3 1 Phospholipase D Active site motif CIAPIN1 PF05093.8 CBZ23636.1 - 2.7e-16 59.4 16.9 5.6e-15 55.2 11.7 2.1 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pkinase PF00069.20 CBZ23638.1 - 1.6e-35 122.5 0.0 1.9e-14 53.4 0.0 3.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23638.1 - 2.7e-15 56.1 0.0 2.4e-10 39.9 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23638.1 - 0.0014 17.6 0.0 0.0074 15.2 0.0 2.1 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 CBZ23638.1 - 0.56 9.2 0.0 1.1 8.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CBZ23638.1 - 2.4 6.9 0.0 3.7 6.3 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Homoserine_dh PF00742.14 CBZ23639.1 - 6.6e-66 221.3 0.0 9.1e-66 220.9 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CBZ23639.1 - 4.4e-10 39.9 0.1 8.6e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Peptidase_M20 PF01546.23 CBZ23640.1 - 3.1e-33 114.8 0.0 4.2e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ23640.1 - 5.7e-19 67.9 0.0 9.1e-19 67.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain HECT PF00632.20 CBZ23641.1 - 1.3e-87 293.9 0.0 1.9e-87 293.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF2413 PF10310.4 CBZ23641.1 - 0.013 14.3 5.3 0.052 12.3 3.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) ZZ PF00569.12 CBZ23641.1 - 0.038 13.5 9.2 0.084 12.4 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF4557 PF15101.1 CBZ23641.1 - 0.2 11.4 8.5 0.47 10.2 5.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DASH_Spc34 PF08657.5 CBZ23641.1 - 0.41 10.2 5.0 0.86 9.2 3.5 1.4 1 0 0 1 1 1 0 DASH complex subunit Spc34 Spore_coat_CotO PF14153.1 CBZ23641.1 - 0.7 9.2 6.8 3.2 7.1 4.7 2.1 1 0 0 1 1 1 0 Spore coat protein CotO Peptidase_S49_N PF08496.5 CBZ23641.1 - 2.3 8.0 6.8 5.4 6.7 4.7 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF972 PF06156.8 CBZ23641.1 - 5.4 7.4 7.5 62 3.9 5.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Ycf1 PF05758.7 CBZ23641.1 - 6.3 4.3 1.8 9.5 3.7 1.2 1.1 1 0 0 1 1 1 0 Ycf1 FadA PF09403.5 CBZ23641.1 - 7.7 6.5 13.5 5.7 6.9 7.4 2.2 2 0 0 2 2 2 0 Adhesion protein FadA Raftlin PF15250.1 CBZ23641.1 - 9.1 4.6 2.0 31 2.9 1.4 1.8 1 0 0 1 1 1 0 Raftlin UPF0172 PF03665.8 CBZ23642.1 - 2.1e-73 246.0 0.0 2.5e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) LRR_4 PF12799.2 CBZ23643.1 - 5.3e-07 29.1 0.2 5e-05 22.8 0.3 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ23643.1 - 0.0011 18.6 0.2 0.0024 17.5 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CBZ23643.1 - 0.015 15.2 2.1 0.23 11.5 0.9 3.0 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_7 PF13504.1 CBZ23643.1 - 0.031 14.4 0.6 9.6 6.9 0.3 3.9 3 0 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 CBZ23643.1 - 0.27 11.4 1.7 6.7 7.1 1.1 3.0 3 0 0 3 3 3 0 Leucine Rich repeat Flagellar_rod PF05149.7 CBZ23644.1 - 7.1e-13 48.4 13.6 7.1e-13 48.4 9.4 2.1 2 0 0 2 2 2 1 Paraflagellar rod protein DUF3275 PF11679.3 CBZ23644.1 - 0.0057 16.3 8.8 2 8.0 0.6 3.6 3 0 0 3 3 3 3 Protein of unknown function (DUF3275) FH2 PF02181.18 CBZ23644.1 - 0.011 14.6 0.8 0.43 9.4 0.1 2.8 2 1 1 3 3 3 0 Formin Homology 2 Domain ABA_GPCR PF12430.3 CBZ23646.1 - 4.6e-39 133.5 0.4 4.6e-39 133.5 0.3 1.7 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CBZ23646.1 - 9.6e-11 41.5 0.0 3.2e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) Lentivirus_VIF PF05851.6 CBZ23646.1 - 0.17 10.5 0.0 0.4 9.3 0.0 1.6 2 0 0 2 2 2 0 Lentivirus virion infectivity factor (VIF) NUDIX PF00293.23 CBZ23647.1 - 1.8e-10 40.5 0.0 3.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DEAD PF00270.24 CBZ23648.1 - 1.1e-42 145.3 0.0 4.5e-42 143.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ23648.1 - 3.8e-21 74.7 0.1 3.7e-20 71.5 0.1 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CBZ23648.1 - 0.0023 17.8 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 CBZ23648.1 - 0.0077 16.0 0.0 0.042 13.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UPF0506 PF11703.3 CBZ23649.1 - 0.068 13.1 2.0 0.13 12.2 1.4 1.4 1 0 0 1 1 1 0 UPF0506 DUF1674 PF07896.7 CBZ23650.1 - 7e-15 54.9 0.2 1e-14 54.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) zf-C3HC4 PF00097.20 CBZ23651.1 - 8.2e-08 31.7 6.8 1.9e-07 30.6 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ23651.1 - 1.1e-07 31.7 7.2 1.1e-07 31.7 5.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ23651.1 - 4.1e-07 29.7 8.0 4.1e-07 29.7 5.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 CBZ23651.1 - 7.7e-07 28.8 6.0 2e-06 27.5 4.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 CBZ23651.1 - 2.5e-06 27.0 6.0 2.5e-06 27.0 4.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ23651.1 - 4e-05 23.2 6.8 9.7e-05 22.0 4.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBZ23651.1 - 0.00023 20.7 5.9 0.00055 19.5 4.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 CBZ23651.1 - 0.00032 20.7 2.8 0.0012 18.9 2.0 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-TRAF PF02176.13 CBZ23651.1 - 0.0011 19.3 0.5 0.0034 17.7 0.3 1.9 1 0 0 1 1 1 1 TRAF-type zinc finger zf-Nse PF11789.3 CBZ23651.1 - 0.0075 15.7 1.8 0.031 13.7 1.3 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Sina PF03145.11 CBZ23651.1 - 0.016 14.8 0.4 0.044 13.4 0.3 1.6 1 0 0 1 1 1 0 Seven in absentia protein family U-box PF04564.10 CBZ23651.1 - 0.017 15.0 0.0 0.094 12.6 0.0 2.3 2 0 0 2 2 2 0 U-box domain DUF1244 PF06844.6 CBZ23651.1 - 0.13 12.1 0.4 0.37 10.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf-Apc11 PF12861.2 CBZ23651.1 - 7.6 6.4 10.6 1 9.2 3.1 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rav1p_C PF12234.3 CBZ23652.1 - 2.8e-34 118.2 0.2 6.2e-25 87.4 1.4 3.4 3 1 0 3 3 3 3 RAVE protein 1 C terminal EamA PF00892.15 CBZ23654.1 - 1.9e-10 40.8 24.4 8.1e-09 35.5 0.2 3.2 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 CBZ23654.1 - 6.4e-07 29.5 20.0 1.5e-05 25.1 0.0 3.8 3 1 1 4 4 4 2 Multidrug resistance efflux transporter UAA PF08449.6 CBZ23654.1 - 0.00055 18.9 3.1 0.00097 18.1 2.1 1.3 1 0 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 CBZ23654.1 - 0.03 13.1 9.6 0.0068 15.2 4.3 1.6 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 CBZ23654.1 - 0.35 10.4 0.0 0.35 10.4 0.0 3.0 3 1 0 3 3 3 0 Triose-phosphate Transporter family SIN1 PF05422.7 CBZ23655.1 - 0.0016 17.0 0.0 0.0023 16.5 0.0 1.2 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) MaoC_dehydratas PF01575.14 CBZ23657.1 - 4.6e-25 87.3 0.0 7.1e-25 86.7 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CBZ23657.1 - 7.8e-10 38.6 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 CBZ23657.1 - 0.021 14.9 0.0 0.055 13.5 0.0 1.7 2 0 0 2 2 2 0 Thioesterase superfamily MaoC_dehydratas PF01575.14 CBZ23658.1 - 4.6e-23 80.9 0.0 8.2e-23 80.1 0.0 1.4 1 1 1 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CBZ23658.1 - 9.1e-13 48.1 0.0 2.9e-12 46.5 0.0 1.7 1 1 1 2 2 2 1 N-terminal half of MaoC dehydratase 4HBT PF03061.17 CBZ23658.1 - 0.00034 20.6 0.0 0.00064 19.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily NOT2_3_5 PF04153.13 CBZ23659.1 - 0.028 14.3 0.6 0.031 14.1 0.4 1.2 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family Acyl-CoA_dh_N PF02771.11 CBZ23660.1 - 7.7e-11 42.5 0.0 2e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBZ23660.1 - 4.6e-06 26.0 0.3 1.1e-05 24.8 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Fascin PF06268.8 CBZ23660.1 - 0.073 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Fascin domain Acyl-CoA_dh_2 PF08028.6 CBZ23660.1 - 0.076 13.2 2.4 1.1 9.4 0.9 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain DUF663 PF04950.7 CBZ23661.1 - 4.2e-79 265.6 0.0 7e-79 264.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CBZ23661.1 - 5.4e-20 70.7 0.0 1.1e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DHC_N2 PF08393.8 CBZ23663.1 - 1.4e-32 112.6 0.0 2.8e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 LRRNT_2 PF08263.7 CBZ23663.1 - 4.2 7.4 8.8 33 4.5 3.5 3.5 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Nucleoplasmin PF03066.10 CBZ23664.1 - 0.061 12.8 1.4 0.1 12.1 1.0 1.3 1 0 0 1 1 1 0 Nucleoplasmin Gly-zipper_OmpA PF13436.1 CBZ23664.1 - 0.54 9.9 11.4 1.1 8.9 7.9 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain PBP1_TM PF14812.1 CBZ23664.1 - 0.89 9.8 10.5 0.04 14.2 2.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L7Ae PF01248.21 CBZ23665.1 - 4.7e-20 70.8 0.4 9.3e-20 69.9 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBZ23665.1 - 0.00011 22.0 0.1 0.00017 21.4 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF1743 PF08489.6 CBZ23665.1 - 0.15 11.7 1.4 0.25 11.1 0.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1743) Ribosomal_L7Ae PF01248.21 CBZ23666.1 - 5.2e-20 70.7 0.3 1.1e-19 69.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CBZ23666.1 - 0.00015 21.6 0.1 0.00023 21.0 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF1743 PF08489.6 CBZ23666.1 - 0.28 10.9 1.9 0.31 10.8 0.3 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1743) Sec20 PF03908.8 CBZ23667.1 - 0.00018 21.1 0.8 0.00049 19.7 0.5 1.9 1 1 0 1 1 1 1 Sec20 V-SNARE_C PF12352.3 CBZ23667.1 - 0.011 15.7 1.6 0.028 14.5 1.1 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus CcmD PF04995.9 CBZ23667.1 - 0.13 11.9 0.5 0.13 11.9 0.3 3.4 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) ADIP PF11559.3 CBZ23667.1 - 0.46 10.3 9.7 0.097 12.5 4.0 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.1 CBZ23667.1 - 0.8 8.6 10.5 1.2 8.0 7.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC-167 PF15188.1 CBZ23667.1 - 9.3 6.2 10.9 3.4 7.6 2.7 2.6 2 2 0 2 2 2 0 Coiled-coil domain-containing protein 167 Mito_carr PF00153.22 CBZ23668.1 - 2.3e-34 116.9 5.3 1.7e-13 50.0 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CP_ATPgrasp_1 PF04174.8 CBZ23668.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Ras PF00071.17 CBZ23671.1 - 8.1e-55 184.6 0.0 9.6e-55 184.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ23671.1 - 7.6e-15 55.4 0.0 1.2e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ23671.1 - 8.3e-11 41.4 0.0 1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ23671.1 - 0.00011 21.6 0.0 0.0017 17.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ23671.1 - 0.0013 18.6 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBZ23671.1 - 0.0015 17.7 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MobB PF03205.9 CBZ23673.1 - 1.6e-08 34.3 0.0 3.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Clp1 PF06807.9 CBZ23673.1 - 0.035 13.8 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 AAA_22 PF13401.1 CBZ23673.1 - 0.12 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBZ23673.1 - 0.22 11.6 0.0 0.49 10.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Nop14 PF04147.7 CBZ23673.1 - 9.9 3.9 9.6 20 2.9 6.6 1.4 1 0 0 1 1 1 0 Nop14-like family Sel1 PF08238.7 CBZ23674.1 - 4.7e-21 74.7 43.0 4.1e-08 33.6 0.0 9.7 10 0 0 10 10 10 8 Sel1 repeat ETF_QO PF05187.8 CBZ23675.1 - 1.1e-39 134.8 0.0 1.8e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CBZ23675.1 - 1.7e-09 37.0 1.4 0.00024 20.1 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBZ23675.1 - 1.2e-08 34.2 2.3 0.00047 19.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CBZ23675.1 - 7.8e-07 29.0 0.2 2.9e-06 27.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CBZ23675.1 - 8.6e-06 25.0 0.1 0.018 14.1 0.2 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.1 CBZ23675.1 - 0.00016 21.4 0.2 0.00031 20.5 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CBZ23675.1 - 0.00037 20.4 0.0 0.0009 19.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ23675.1 - 0.0013 19.0 0.2 0.45 10.9 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBZ23675.1 - 0.0045 15.5 0.3 0.0069 14.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 CBZ23675.1 - 0.0079 14.8 0.4 0.074 11.6 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 CBZ23675.1 - 0.01 14.7 0.1 0.015 14.2 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 CBZ23675.1 - 0.028 13.4 0.9 0.038 13.0 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 CBZ23675.1 - 0.029 14.4 0.2 0.055 13.5 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBZ23675.1 - 0.035 13.1 0.4 0.055 12.5 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fer4_7 PF12838.2 CBZ23675.1 - 0.077 13.3 0.8 0.21 11.9 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_13 PF13166.1 CBZ23678.1 - 0.01 14.3 9.6 0.014 13.8 6.6 1.1 1 0 0 1 1 1 0 AAA domain Cytochrom_B562 PF07361.6 CBZ23678.1 - 0.12 12.7 8.7 1.7 9.0 0.8 3.0 1 1 2 3 3 3 0 Cytochrome b562 Ax_dynein_light PF10211.4 CBZ23678.1 - 0.14 11.9 11.1 0.04 13.7 1.8 3.4 2 1 2 4 4 4 0 Axonemal dynein light chain Bacillus_HBL PF05791.6 CBZ23678.1 - 0.2 10.9 1.1 4.1 6.7 0.2 2.5 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) THOC7 PF05615.8 CBZ23678.1 - 0.36 11.0 18.2 0.44 10.8 3.6 3.3 2 1 1 3 3 3 0 Tho complex subunit 7 Syntaxin PF00804.20 CBZ23678.1 - 0.4 10.8 6.0 3.7 7.7 4.2 2.7 1 1 0 1 1 1 0 Syntaxin DUF1192 PF06698.6 CBZ23678.1 - 0.67 9.8 28.1 0.86 9.4 2.0 5.2 4 1 1 5 5 5 0 Protein of unknown function (DUF1192) FlaC_arch PF05377.6 CBZ23678.1 - 0.82 9.6 3.3 10 6.0 0.0 3.8 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 CBZ23678.1 - 1.3 9.4 15.1 3.8 7.8 0.3 4.7 3 1 2 5 5 5 0 Protein of unknown function (DUF972) Pox_A_type_inc PF04508.7 CBZ23678.1 - 2.1 8.3 0.0 2.1 8.3 0.0 5.7 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat TBPIP PF07106.8 CBZ23678.1 - 2.6 7.5 11.1 0.97 8.9 0.9 3.1 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 CBZ23678.1 - 2.7 7.6 21.6 0.59 9.7 6.0 3.0 2 1 1 3 3 3 0 Mnd1 family Syntaxin-6_N PF09177.6 CBZ23678.1 - 3.5 8.0 9.1 1.1 9.6 1.5 3.1 1 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF812 PF05667.6 CBZ23678.1 - 6.8 5.0 18.1 22 3.3 12.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Kinesin-relat_1 PF12711.2 CBZ23678.1 - 7.5 7.0 19.4 5.7 7.4 1.2 4.4 3 1 1 4 4 4 0 Kinesin motor Kinetocho_Slk19 PF12709.2 CBZ23678.1 - 8.7 6.4 18.6 5.2 7.2 0.3 4.7 3 1 2 5 5 5 0 Central kinetochore-associated E1-E2_ATPase PF00122.15 CBZ23679.1 - 4.8e-54 182.8 0.1 4.8e-54 182.8 0.0 2.0 2 1 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBZ23679.1 - 1.8e-38 131.8 5.0 4.2e-38 130.6 3.5 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBZ23679.1 - 2.8e-23 83.4 0.0 1.6e-22 81.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBZ23679.1 - 4.4e-15 54.8 0.0 9.9e-15 53.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CBZ23679.1 - 5.2e-11 42.3 0.0 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBZ23679.1 - 5.6e-11 42.9 0.0 1.8e-10 41.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBZ23679.1 - 1.3e-05 24.9 0.1 0.0004 20.0 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase JAB PF01398.16 CBZ23680.1 - 0.028 14.1 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3539 PF12058.3 CBZ23680.1 - 0.035 13.9 0.2 0.39 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3539) E1-E2_ATPase PF00122.15 CBZ23681.1 - 2.1e-54 184.0 0.6 4.9e-54 182.8 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBZ23681.1 - 3.6e-38 130.9 3.8 8.1e-38 129.7 2.7 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBZ23681.1 - 2.9e-23 83.4 0.0 1.6e-22 81.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBZ23681.1 - 4.8e-15 54.7 0.0 1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBZ23681.1 - 4.4e-11 43.2 0.0 1.8e-10 41.3 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ23681.1 - 5.3e-11 42.3 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBZ23681.1 - 7e-06 25.7 0.0 0.0004 20.0 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase V-SNARE_C PF12352.3 CBZ23683.1 - 3.1e-08 33.5 4.0 4.8e-08 32.9 2.7 1.2 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.6 CBZ23683.1 - 0.036 11.6 0.3 0.048 11.2 0.2 1.1 1 0 0 1 1 1 0 Prominin ATG16 PF08614.6 CBZ23683.1 - 0.037 13.8 0.2 0.046 13.5 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Synaptobrevin PF00957.16 CBZ23683.1 - 0.43 10.2 2.5 1.7 8.3 1.7 1.9 1 1 0 1 1 1 0 Synaptobrevin FAM163 PF15069.1 CBZ23683.1 - 2.4 8.7 6.8 2.6 8.5 0.8 2.3 2 1 0 2 2 2 0 FAM163 family Adeno_PIX PF03955.9 CBZ23683.1 - 4.3 7.9 6.1 1.8 9.1 1.0 2.0 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Ribosomal_S4 PF00163.14 CBZ23684.1 - 7.2e-29 100.0 0.4 1.5e-28 99.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CBZ23684.1 - 5.8e-14 51.2 0.4 1.3e-13 50.1 0.3 1.6 1 0 0 1 1 1 1 S4 domain Pkinase PF00069.20 CBZ23685.1 - 3.7e-42 144.2 0.0 1.2e-26 93.4 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23685.1 - 2.7e-22 79.1 0.0 4.8e-16 58.6 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase NTP_transf_2 PF01909.18 CBZ23686.1 - 0.0027 17.9 0.1 0.0059 16.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CBZ23686.1 - 0.0049 16.7 0.0 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 Cid1 family poly A polymerase OmpW PF03922.9 CBZ23686.1 - 0.15 11.6 0.1 0.28 10.8 0.1 1.3 1 0 0 1 1 1 0 OmpW family EF-hand_1 PF00036.27 CBZ23687.1 - 8.2e-27 90.4 9.0 4.9e-09 34.8 0.5 4.4 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 CBZ23687.1 - 1.9e-22 79.1 4.5 3.1e-12 46.4 0.6 2.9 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ23687.1 - 2.5e-22 76.6 3.1 5.1e-09 35.2 0.1 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 CBZ23687.1 - 1.3e-18 66.3 9.7 1.7e-13 49.9 0.7 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBZ23687.1 - 4.7e-17 60.4 10.2 4.5e-06 25.7 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CBZ23687.1 - 9.3e-10 38.2 0.1 5.3e-05 23.0 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.2 CBZ23687.1 - 1.4e-06 27.9 0.6 0.0081 15.8 0.0 2.6 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand HEAT_2 PF13646.1 CBZ23689.1 - 4.2e-13 49.3 26.7 3.1e-05 24.1 0.0 9.5 6 4 2 8 8 8 3 HEAT repeats HEAT PF02985.17 CBZ23689.1 - 4e-11 42.0 22.5 0.0021 17.9 0.2 10.7 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 CBZ23689.1 - 9.1e-07 29.1 40.3 0.028 14.8 0.2 12.1 11 1 1 12 12 12 3 HEAT-like repeat CLASP_N PF12348.3 CBZ23689.1 - 2.7e-05 23.6 0.3 0.21 10.9 0.1 3.6 3 1 0 3 3 3 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 CBZ23689.1 - 0.0055 17.0 0.1 1.8 8.9 0.0 4.3 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 CBZ23689.1 - 0.0067 16.3 0.2 0.062 13.2 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3554 PF12074.3 CBZ23689.1 - 0.02 14.3 0.0 0.21 10.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3554) MMS19_C PF12460.3 CBZ23689.1 - 0.023 13.4 0.1 0.1 11.2 0.0 2.1 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 CBZ23689.1 - 0.025 12.9 0.1 5.1 5.2 0.0 3.2 3 0 0 3 3 3 0 Adaptin N terminal region Arm PF00514.18 CBZ23689.1 - 0.26 11.1 7.6 3.2 7.7 0.0 5.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat MCD PF05292.6 CBZ23690.1 - 2.9e-55 187.3 0.0 4.5e-34 117.6 0.0 2.8 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase (MCD) PPI_Ypi1 PF07491.6 CBZ23692.1 - 1.8e-17 62.6 4.0 4.5e-17 61.4 2.8 1.7 1 1 0 1 1 1 1 Protein phosphatase inhibitor SR-25 PF10500.4 CBZ23692.1 - 0.052 13.0 1.5 0.085 12.3 1.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IgaA PF07095.6 CBZ23693.1 - 0.15 9.7 0.0 0.2 9.3 0.0 1.1 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA His_Phos_1 PF00300.17 CBZ23694.1 - 5.3e-27 94.8 0.1 1.1e-26 93.8 0.1 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.13 CBZ23694.1 - 2.9e-16 59.2 0.6 3.6e-09 36.0 0.0 3.4 3 0 0 3 3 3 3 6-phosphofructo-2-kinase AAA_33 PF13671.1 CBZ23694.1 - 0.0025 17.7 0.0 0.15 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBZ23694.1 - 0.11 13.3 0.0 0.36 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF739 PF05339.6 CBZ23694.1 - 0.24 11.2 0.0 0.42 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF739) DnaJ PF00226.26 CBZ23695.1 - 1.1e-07 31.4 0.0 3.8e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain Med3 PF11593.3 CBZ23695.1 - 8.8 5.4 9.9 12 4.9 6.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAD_binding_2 PF00890.19 CBZ23698.1 - 3.2e-75 253.5 8.4 4.2e-75 253.1 5.8 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 CBZ23698.1 - 3.7e-20 71.5 0.0 1.6e-19 69.4 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 CBZ23698.1 - 4.8e-10 38.8 3.5 1.4e-07 30.7 0.5 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CBZ23698.1 - 6.3e-09 35.4 7.4 9.3e-09 34.8 3.3 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBZ23698.1 - 1.3e-07 31.4 1.9 6.1e-07 29.3 1.3 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CBZ23698.1 - 3.6e-07 29.0 3.6 0.00033 19.2 0.2 3.1 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 CBZ23698.1 - 2.4e-06 27.5 2.4 0.00075 19.4 0.1 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBZ23698.1 - 3.4e-05 22.8 1.3 0.0021 16.9 0.5 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 CBZ23698.1 - 0.00024 21.2 0.1 0.00068 19.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBZ23698.1 - 0.02 13.9 3.5 1.1 8.3 0.0 2.8 3 0 0 3 3 3 0 Thi4 family GMC_oxred_N PF00732.14 CBZ23698.1 - 0.094 11.8 0.4 0.23 10.5 0.0 1.7 2 0 0 2 2 2 0 GMC oxidoreductase RRM_6 PF14259.1 CBZ23699.1 - 0.00016 21.5 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ23699.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tox-HNH-HHH PF15637.1 CBZ23699.1 - 0.29 10.9 3.4 0.3 10.8 1.4 1.7 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif PGM_PMM_I PF02878.11 CBZ23700.1 - 1.2e-12 47.4 0.0 8.6e-09 34.9 0.0 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 CBZ23700.1 - 1.3e-07 31.4 0.1 3.3e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 CBZ23700.1 - 1.5e-07 31.6 0.0 6.3e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CBZ23700.1 - 0.0039 17.2 0.1 0.0078 16.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III UQ_con PF00179.21 CBZ23705.1 - 4.5e-38 129.8 0.0 6.1e-38 129.4 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ23705.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RRM_5 PF13893.1 CBZ23707.1 - 0.0013 18.5 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CBZ23708.1 - 2.3e-56 190.8 0.0 3.6e-56 190.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23708.1 - 1e-35 123.0 0.0 6.5e-35 120.4 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase PX PF00787.19 CBZ23708.1 - 0.0065 16.2 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 PX domain RuvA_N PF01330.16 CBZ23708.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 RuvA N terminal domain Kinase-like PF14531.1 CBZ23708.1 - 0.17 10.8 0.0 0.36 9.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 CBZ23710.1 - 2e-76 256.6 0.0 2.2e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23710.1 - 3e-39 134.6 0.0 3.6e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23710.1 - 2.2e-09 36.7 0.0 6.5e-08 31.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CBZ23710.1 - 0.0029 17.3 0.1 0.21 11.3 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ23710.1 - 0.003 16.6 0.1 0.0054 15.8 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBZ23710.1 - 0.0048 16.2 0.1 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family PKD_channel PF08016.7 CBZ23711.1 - 0.0033 15.9 15.2 0.005 15.3 10.5 1.1 1 0 0 1 1 1 1 Polycystin cation channel DUF3608 PF12257.3 CBZ23712.1 - 1.7e-16 59.9 0.4 1e-10 41.0 0.0 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF3608) Radial_spoke PF04712.7 CBZ23713.1 - 3.6e-08 32.6 3.6 2.7e-05 23.1 0.0 2.7 2 1 0 2 2 2 2 Radial spokehead-like protein CENP-B_dimeris PF09026.5 CBZ23713.1 - 0.0012 19.0 3.9 0.0021 18.2 2.7 1.4 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Myc_N PF01056.13 CBZ23713.1 - 0.03 13.5 4.7 0.041 13.0 3.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region BNR PF02012.15 CBZ23713.1 - 0.034 13.9 0.9 0.078 12.8 0.6 1.7 1 0 0 1 1 1 0 BNR/Asp-box repeat PBP1_TM PF14812.1 CBZ23713.1 - 0.17 12.1 4.2 0.32 11.3 2.9 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 CBZ23713.1 - 0.24 10.9 6.9 0.36 10.3 4.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin Mis14 PF08641.7 CBZ23713.1 - 0.25 11.4 5.3 0.38 10.8 3.7 1.2 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Sigma70_ner PF04546.8 CBZ23713.1 - 0.38 10.3 8.8 0.54 9.8 6.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 CBZ23713.1 - 0.65 9.7 2.8 1.2 8.9 2.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.1 CBZ23713.1 - 0.68 9.6 2.8 1.1 8.8 2.0 1.3 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.8 CBZ23713.1 - 2.8 5.6 10.9 3.6 5.2 7.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi Ribosomal_60s PF00428.14 CBZ23713.1 - 3.7 7.9 16.0 6.4 7.2 11.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein TRAP_alpha PF03896.11 CBZ23713.1 - 4.5 6.1 5.5 6.2 5.7 3.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3437 PF11919.3 CBZ23714.1 - 7.6e-21 73.6 0.0 3.5e-20 71.4 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Nucleoplasmin PF03066.10 CBZ23718.1 - 4.4e-06 26.2 0.1 5e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Nucleoplasmin Nucleoplasmin PF03066.10 CBZ23719.1 - 4.8e-06 26.1 0.7 4.8e-06 26.1 0.5 4.2 1 1 2 3 3 3 1 Nucleoplasmin DUF59 PF01883.14 CBZ23721.1 - 1e-08 35.0 0.0 2.3e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF59 Glyco_hydro_1 PF00232.13 CBZ23721.1 - 0.077 11.1 0.0 0.077 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 PIF1 PF05970.9 CBZ23722.1 - 1.4e-43 149.3 0.0 8.1e-35 120.4 0.0 3.1 3 0 0 3 3 3 2 PIF1-like helicase Herpes_Helicase PF02689.9 CBZ23722.1 - 6.6e-12 44.0 1.8 8.7e-07 27.0 0.1 2.1 2 0 0 2 2 2 2 Helicase AAA_30 PF13604.1 CBZ23722.1 - 2.3e-11 43.6 0.0 5.8e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ23722.1 - 3.9e-07 29.7 0.3 2.3e-06 27.2 0.2 2.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CBZ23722.1 - 7.2e-07 29.4 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CBZ23722.1 - 3e-05 23.6 0.1 0.00076 19.0 0.0 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CBZ23722.1 - 0.00018 20.4 0.0 0.00042 19.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_5 PF07728.9 CBZ23722.1 - 0.00024 20.8 0.0 0.00068 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ23722.1 - 0.0012 18.8 0.3 0.0064 16.5 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 CBZ23722.1 - 0.003 17.1 0.1 1.8 8.1 0.0 3.3 2 1 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.1 CBZ23722.1 - 0.0075 16.3 0.0 0.031 14.4 0.0 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AFG1_ATPase PF03969.11 CBZ23722.1 - 0.012 14.5 0.0 0.022 13.5 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase NACHT PF05729.7 CBZ23722.1 - 0.015 15.0 0.1 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 CBZ23722.1 - 0.035 13.8 0.3 1.3 8.6 0.3 2.4 2 0 0 2 2 2 0 NTPase PhoH PF02562.11 CBZ23722.1 - 0.071 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 CBZ23722.1 - 0.076 13.3 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 CBZ23722.1 - 0.1 11.5 0.2 0.2 10.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 CBZ23722.1 - 0.16 11.4 0.1 0.43 10.0 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 CBZ23722.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 CBZ23722.1 - 0.31 10.6 0.0 0.58 9.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Rotamase PF00639.16 CBZ23723.1 - 1.4e-23 83.3 0.0 1.6e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CBZ23723.1 - 5.2e-16 58.9 0.0 5.9e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CBZ23723.1 - 0.0015 19.1 0.0 0.002 18.7 0.0 1.2 1 1 0 1 1 1 1 PPIC-type PPIASE domain Exonuc_VII_S PF02609.11 CBZ23723.1 - 0.007 16.1 0.2 0.087 12.6 0.0 2.1 2 0 0 2 2 2 1 Exonuclease VII small subunit DSX_dimer PF08828.5 CBZ23723.1 - 0.078 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Doublesex dimerisation domain Sel1 PF08238.7 CBZ23725.1 - 5e-09 36.4 5.4 0.0096 16.5 3.5 3.9 3 1 0 3 3 3 2 Sel1 repeat Phytoreo_Pns PF05451.6 CBZ23725.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 E1-E2_ATPase PF00122.15 CBZ23726.1 - 4.1e-24 84.8 0.1 6.3e-23 81.0 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CBZ23726.1 - 5e-22 79.0 0.0 1e-21 78.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBZ23726.1 - 2.7e-18 67.1 0.0 3.8e-17 63.4 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ23726.1 - 6.7e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBZ23726.1 - 0.017 14.7 0.3 0.054 13.0 0.1 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Dpy-30 PF05186.8 CBZ23727.1 - 8.2e-12 44.4 0.0 1.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif BPL_LplA_LipB PF03099.14 CBZ23728.1 - 3.7e-19 68.9 0.0 7.4e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family zf-C2H2 PF00096.21 CBZ23729.1 - 2.9e-07 30.4 7.0 0.0012 19.0 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBZ23729.1 - 4.1e-05 23.6 7.4 0.12 12.8 1.3 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CBZ23729.1 - 0.001 19.1 1.2 0.2 11.8 0.1 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 CBZ23729.1 - 0.0023 18.0 1.2 0.77 9.9 0.3 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.2 CBZ23729.1 - 0.0028 17.5 5.1 0.0047 16.8 0.8 2.5 2 0 0 2 2 2 1 Zinc-binding DUF629 PF04780.7 CBZ23729.1 - 0.012 14.2 0.2 0.62 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.1 CBZ23729.1 - 0.013 15.4 2.6 1.5 8.8 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 CBZ23729.1 - 0.034 14.3 1.1 0.034 14.3 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type TFIIS_C PF01096.13 CBZ23729.1 - 0.054 13.1 3.4 0.38 10.4 0.4 2.6 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) CpXC PF14353.1 CBZ23729.1 - 0.095 12.6 0.2 6.8 6.6 0.0 2.2 2 0 0 2 2 2 0 CpXC protein zinc_ribbon_5 PF13719.1 CBZ23729.1 - 0.58 9.7 4.0 17 5.1 0.2 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_jaz PF12171.3 CBZ23729.1 - 0.67 10.1 3.1 0.44 10.7 0.6 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CBZ23729.1 - 0.82 10.0 8.9 3.6 8.0 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain DUF1601 PF07671.6 CBZ23730.1 - 0.0064 16.1 0.1 0.025 14.1 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1601) Reo_sigmaC PF04582.7 CBZ23730.1 - 0.24 10.5 4.4 0.19 10.8 1.9 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein ERM PF00769.14 CBZ23730.1 - 0.62 9.5 32.7 1.5 8.3 22.6 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Macoilin PF09726.4 CBZ23730.1 - 0.75 8.0 22.7 1.5 6.9 15.8 1.5 1 0 0 1 1 1 0 Transmembrane protein AAA_13 PF13166.1 CBZ23730.1 - 2 6.7 10.9 2.8 6.2 7.6 1.2 1 0 0 1 1 1 0 AAA domain XkdW PF09636.5 CBZ23730.1 - 10 6.0 6.5 1 9.2 0.9 2.1 2 0 0 2 2 2 0 XkdW protein FA_desaturase PF00487.19 CBZ23731.1 - 7.5e-46 156.6 20.6 7.5e-46 156.6 14.3 1.5 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 CBZ23731.1 - 0.037 13.8 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain DUF4140 PF13600.1 CBZ23734.1 - 0.67 10.4 4.3 11 6.4 0.8 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) VWA_2 PF13519.1 CBZ23735.1 - 2.1e-10 41.0 0.2 2.1e-10 41.0 0.2 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 CBZ23735.1 - 0.00013 21.2 14.0 0.0047 16.3 1.7 3.6 3 0 0 3 3 3 2 Ubiquitin interaction motif Miro PF08477.8 CBZ23736.1 - 0.0053 17.2 0.0 0.009 16.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PMSR PF01625.16 CBZ23737.1 - 5.3e-57 192.0 0.3 7e-57 191.6 0.2 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Chorein_N PF12624.2 CBZ23738.1 - 2.3e-06 27.1 0.0 5.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Aa_trans PF01490.13 CBZ23739.1 - 1.6e-57 194.8 22.0 1.8e-57 194.6 15.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ23739.1 - 4.7e-11 42.1 10.4 4.7e-11 42.1 7.2 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family EVC2_like PF12297.3 CBZ23739.1 - 1.2 7.7 2.1 2.1 6.8 0.2 1.9 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Galactosyl_T PF01762.16 CBZ23740.1 - 0.00033 20.3 0.2 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase Ribosomal_S19e PF01090.14 CBZ23742.1 - 3.6e-45 152.8 0.0 4.2e-45 152.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF1738 PF08401.6 CBZ23744.1 - 0.036 13.7 0.0 8.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) RRM_1 PF00076.17 CBZ23745.1 - 6.5e-18 64.1 0.0 9.4e-18 63.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23745.1 - 5e-12 45.6 0.0 8.8e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ23745.1 - 7.3e-10 38.5 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_6 PF13516.1 CBZ23747.1 - 1.9e-30 101.4 23.7 0.0054 16.6 0.3 13.1 13 0 0 13 13 13 7 Leucine Rich repeat LRR_1 PF00560.28 CBZ23747.1 - 2.6e-14 51.0 11.6 2.1 8.6 0.0 10.6 10 1 0 10 10 10 3 Leucine Rich Repeat LRR_4 PF12799.2 CBZ23747.1 - 5.3e-13 48.2 13.9 0.064 12.9 0.1 7.2 5 2 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ23747.1 - 2.9e-07 30.1 19.2 0.28 10.9 0.6 6.7 4 2 3 7 7 7 6 Leucine rich repeat SPX PF03105.14 CBZ23747.1 - 0.0078 16.0 0.7 0.011 15.5 0.5 1.3 1 0 0 1 1 1 1 SPX domain LRR_7 PF13504.1 CBZ23747.1 - 0.016 15.3 26.6 12 6.6 0.0 9.5 10 0 0 10 10 10 0 Leucine rich repeat Occludin_ELL PF07303.8 CBZ23747.1 - 0.46 11.2 6.4 0.18 12.5 2.3 2.0 2 0 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.7 CBZ23747.1 - 2 8.2 8.6 5.5 6.7 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4337 PF14235.1 CBZ23747.1 - 8.5 6.1 9.1 42 3.9 0.1 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) IU_nuc_hydro PF01156.14 CBZ23748.1 - 3.3e-50 171.0 0.1 3.9e-50 170.8 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Tim17 PF02466.14 CBZ23749.1 - 0.047 13.7 2.7 0.098 12.6 1.8 1.6 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family DUF4131 PF13567.1 CBZ23749.1 - 0.14 11.5 1.1 3 7.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Mito_carr PF00153.22 CBZ23750.1 - 5.5e-62 205.5 0.8 6.4e-22 77.0 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Trypsin_2 PF13365.1 CBZ23751.1 - 0.011 15.7 0.8 0.026 14.5 0.6 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S29 PF02907.10 CBZ23751.1 - 0.082 12.4 0.2 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_C4 PF00863.14 CBZ23751.1 - 0.098 11.5 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C4 TPR_19 PF14559.1 CBZ23752.1 - 2e-13 50.4 2.8 0.0031 17.8 0.1 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ23752.1 - 1.1e-10 41.8 3.0 0.0061 17.2 0.0 4.4 4 1 1 5 5 4 4 Tetratricopeptide repeat Apc3 PF12895.2 CBZ23752.1 - 1.2e-08 34.9 15.2 0.11 12.6 0.6 5.0 2 2 3 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CBZ23752.1 - 6.7e-08 31.8 21.8 0.045 13.6 0.0 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ23752.1 - 1.1e-06 28.1 1.8 1.1e-06 28.1 1.3 4.3 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.1 CBZ23752.1 - 5.2e-05 23.5 6.4 0.86 10.4 0.1 5.2 5 1 1 6 6 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ23752.1 - 0.00058 19.3 17.2 0.11 12.1 0.2 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ23752.1 - 0.01 16.2 10.9 11 6.7 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ23752.1 - 0.015 15.0 5.0 0.28 11.0 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ23752.1 - 0.025 14.4 0.5 4.5 7.2 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ23752.1 - 0.23 11.4 14.8 3.4 7.6 0.0 5.3 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ23752.1 - 0.55 10.5 3.2 8.8 6.8 0.0 4.0 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ23752.1 - 0.84 9.5 14.9 4.3 7.3 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ATP-synt_DE PF00401.15 CBZ23753.1 - 0.41 10.5 3.8 0.64 9.9 2.7 1.3 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Actin PF00022.14 CBZ23754.1 - 2.4e-18 65.7 0.0 1.5e-12 46.7 0.0 2.3 2 0 0 2 2 2 2 Actin START PF01852.14 CBZ23755.1 - 4e-25 88.3 0.0 6.2e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 START domain Pkinase PF00069.20 CBZ23756.1 - 2.3e-33 115.4 0.0 4.2e-31 108.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23756.1 - 2.1e-17 63.0 0.0 2.9e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ23756.1 - 0.0015 17.6 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBZ23756.1 - 0.046 13.0 0.0 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Beta_helix PF13229.1 CBZ23757.1 - 6.6e-19 68.1 0.6 1.1e-17 64.2 0.5 2.1 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 CBZ23757.1 - 4.9e-12 45.4 0.0 7e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.2 CBZ23757.1 - 0.00034 20.8 0.5 0.0013 18.8 0.3 2.2 1 1 0 1 1 1 1 Pectate lyase superfamily protein DUF1565 PF07602.6 CBZ23757.1 - 0.0081 15.3 0.0 1.6 7.7 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF1565) Phage_Coat_A PF05357.8 CBZ23759.1 - 4.2 7.0 11.8 1.7 8.2 0.1 3.0 3 0 0 3 3 3 0 Phage Coat Protein A PDEase_I PF00233.14 CBZ23760.1 - 2.6e-35 122.2 0.0 6.8e-35 120.9 0.0 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.16 CBZ23760.1 - 1.6e-08 34.3 13.3 4e-08 33.0 9.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger TMF_DNA_bd PF12329.3 CBZ23760.1 - 0.0058 16.4 3.7 0.0058 16.4 2.6 8.0 6 2 1 8 8 8 3 TATA element modulatory factor 1 DNA binding XLF PF09302.6 CBZ23760.1 - 4.2 7.1 13.7 0.08 12.7 0.4 3.7 2 1 2 4 4 4 0 XLF (XRCC4-like factor) Pkinase PF00069.20 CBZ23761.1 - 3.5e-64 216.4 0.0 4.9e-64 215.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23761.1 - 5.3e-41 140.4 0.0 7.7e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23761.1 - 2.6e-06 26.5 0.0 1.9e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBZ23761.1 - 0.00047 19.9 0.1 0.41 10.3 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family KdpD PF02702.12 CBZ23761.1 - 0.034 13.2 0.1 0.075 12.1 0.1 1.5 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Helicase_C_2 PF13307.1 CBZ23762.1 - 7.4e-50 169.1 0.0 2.3e-49 167.5 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBZ23762.1 - 3.1e-42 143.9 0.1 1.3e-41 141.8 0.0 1.9 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.24 CBZ23762.1 - 0.00012 21.5 0.0 0.0085 15.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ23762.1 - 0.00015 21.6 0.0 0.005 16.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2017 PF09438.5 CBZ23762.1 - 0.0035 16.9 0.1 0.0084 15.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2017) PhoH PF02562.11 CBZ23762.1 - 0.011 15.0 0.0 28 3.8 0.0 4.0 4 0 0 4 4 4 0 PhoH-like protein AAA_11 PF13086.1 CBZ23762.1 - 0.035 13.6 0.0 0.27 10.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain SNF2_N PF00176.18 CBZ23762.1 - 0.057 12.1 0.0 0.32 9.7 0.0 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain Cnd3 PF12719.2 CBZ23763.1 - 2.3e-42 145.0 0.7 2.3e-42 145.0 0.5 2.3 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 CBZ23763.1 - 5.5e-06 26.0 9.9 4.8 7.5 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 CBZ23763.1 - 1.5e-05 25.2 13.0 0.0017 18.5 0.1 6.1 4 3 1 6 6 6 2 HEAT repeats DUF3458 PF11940.3 CBZ23763.1 - 0.042 12.6 6.8 0.27 10.0 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Neurochondrin PF05536.6 CBZ23764.1 - 0.00061 18.2 1.1 0.0076 14.6 0.0 2.6 3 0 0 3 3 3 1 Neurochondrin Proteasom_PSMB PF10508.4 CBZ23764.1 - 0.0074 14.6 0.3 0.1 10.8 0.0 2.7 2 1 0 3 3 3 1 Proteasome non-ATPase 26S subunit Arm PF00514.18 CBZ23764.1 - 0.011 15.5 6.0 2.3 8.1 0.3 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat SAM_1 PF00536.25 CBZ23765.1 - 9e-05 22.5 0.0 0.00032 20.8 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBZ23765.1 - 0.0015 18.3 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CAP_N PF01213.14 CBZ23765.1 - 0.013 14.8 0.7 0.093 11.9 0.1 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MIT PF04212.13 CBZ23765.1 - 0.014 15.2 0.1 0.082 12.7 0.1 2.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain CBF PF03914.12 CBZ23765.1 - 0.16 11.3 1.3 0.37 10.2 0.0 2.2 3 0 0 3 3 3 0 CBF/Mak21 family DnaB_bind PF10410.4 CBZ23765.1 - 0.22 11.5 5.5 2.2 8.3 0.0 4.0 3 1 1 4 4 4 0 DnaB-helicase binding domain of primase Lge1 PF11488.3 CBZ23767.1 - 0.042 14.0 12.1 0.25 11.5 0.2 4.6 5 0 0 5 5 5 0 Transcriptional regulatory protein LGE1 GAS PF13851.1 CBZ23767.1 - 0.045 12.9 8.4 0.057 12.6 3.7 2.7 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3571 PF12095.3 CBZ23767.1 - 2 8.7 6.0 3.9 7.7 0.6 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3571) PAP_central PF04928.12 CBZ23768.1 - 6.7e-43 146.3 0.0 9e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CBZ23768.1 - 1.6e-05 24.4 0.0 2.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CBZ23768.1 - 0.0024 18.1 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DCX PF03607.12 CBZ23769.1 - 2.1e-05 24.0 0.1 6.4e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Doublecortin Pkinase PF00069.20 CBZ23771.1 - 5.8e-64 215.7 0.0 8.9e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23771.1 - 1.5e-44 152.0 0.0 2.8e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23771.1 - 1.7e-06 27.1 0.0 2.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ23771.1 - 0.072 12.8 0.1 7.3 6.2 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF4586 PF15239.1 CBZ23772.1 - 1.7e-67 228.1 12.4 2.1e-67 227.8 8.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) TPR_19 PF14559.1 CBZ23773.1 - 6.2e-21 74.5 19.8 3.5e-05 24.0 0.6 9.2 7 3 3 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ23773.1 - 1.8e-19 68.4 32.1 0.00069 20.0 0.1 10.2 8 1 2 10 10 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ23773.1 - 8.1e-14 51.8 42.5 4.4e-05 24.0 1.6 10.7 10 2 2 12 12 11 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ23773.1 - 2.3e-13 49.5 21.5 0.014 15.0 0.0 9.5 9 1 1 10 10 10 5 TPR repeat TPR_17 PF13431.1 CBZ23773.1 - 9.3e-08 31.6 5.2 9.4 6.7 0.1 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ23773.1 - 1.5e-06 28.2 16.0 0.061 13.4 0.0 6.1 6 1 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBZ23773.1 - 2.8e-06 27.1 30.3 0.02 14.7 0.5 8.5 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ23773.1 - 2.9e-05 23.6 26.7 0.14 12.1 0.0 10.1 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ23773.1 - 0.00015 21.2 3.3 0.52 10.0 0.0 6.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ23773.1 - 0.0022 18.3 16.0 0.18 12.3 0.0 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat Topoisom_bac PF01131.15 CBZ23773.1 - 0.0034 16.2 0.3 0.0064 15.3 0.2 1.4 1 0 0 1 1 1 1 DNA topoisomerase TPR_20 PF14561.1 CBZ23773.1 - 0.0041 17.2 7.3 0.0081 16.2 0.3 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ23773.1 - 0.043 14.2 40.9 3.4 8.3 0.1 9.9 9 0 0 9 9 9 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 CBZ23773.1 - 0.88 9.0 18.0 0.074 12.5 0.4 4.7 4 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.1 CBZ23773.1 - 4.2 7.2 17.7 1.9 8.4 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Nol1_Nop2_Fmu PF01189.12 CBZ23774.1 - 1.4e-32 113.1 0.0 2.9e-29 102.3 0.0 2.1 2 0 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CBZ23774.1 - 5.6e-06 26.4 0.0 1.4e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CBZ23774.1 - 0.0086 15.6 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain zf-MIZ PF02891.15 CBZ23776.1 - 4.1e-09 35.8 1.8 2e-08 33.6 0.0 2.7 3 0 0 3 3 3 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CBZ23776.1 - 0.059 12.8 0.1 0.13 11.7 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Glucodextran_B PF09136.5 CBZ23776.1 - 2.4 8.3 6.1 6.8 6.9 0.2 3.2 3 0 0 3 3 3 0 Glucodextranase, domain B PFK PF00365.15 CBZ23777.1 - 1.4e-37 129.1 1.2 2.1e-37 128.6 0.8 1.2 1 0 0 1 1 1 1 Phosphofructokinase NAD_kinase PF01513.16 CBZ23777.1 - 0.00011 21.0 0.0 0.00022 20.1 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DUF3813 PF12758.2 CBZ23777.1 - 0.13 12.3 0.1 0.37 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) AAA PF00004.24 CBZ23778.1 - 2.9e-40 137.5 0.0 6.9e-40 136.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBZ23778.1 - 4.9e-27 93.6 0.2 1.3e-26 92.2 0.2 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CBZ23778.1 - 6.2e-20 70.8 2.8 9.4e-20 70.2 1.0 2.1 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 CBZ23778.1 - 1.9e-06 28.6 0.3 1.1e-05 26.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CBZ23778.1 - 5e-06 26.5 0.0 1.2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBZ23778.1 - 1.4e-05 25.1 0.5 0.00031 20.9 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CBZ23778.1 - 2.1e-05 24.6 0.1 0.00018 21.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CBZ23778.1 - 3.2e-05 23.4 0.6 0.19 11.1 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 CBZ23778.1 - 8.1e-05 22.3 0.0 0.00043 20.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CBZ23778.1 - 0.00018 21.0 0.0 0.00034 20.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 CBZ23778.1 - 0.00031 20.4 0.2 0.0074 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBZ23778.1 - 0.00032 20.5 0.0 0.00094 19.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBZ23778.1 - 0.0004 19.3 0.0 0.00068 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CBZ23778.1 - 0.00065 19.5 0.0 0.002 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ23778.1 - 0.00068 18.7 0.0 0.0014 17.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CBZ23778.1 - 0.002 16.9 0.0 0.0031 16.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus USP8_dimer PF08969.6 CBZ23778.1 - 0.0067 16.3 3.2 0.017 15.0 2.2 1.6 1 0 0 1 1 1 1 USP8 dimerisation domain RNA_helicase PF00910.17 CBZ23778.1 - 0.0079 16.3 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 CBZ23778.1 - 0.0089 16.3 0.1 0.031 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBZ23778.1 - 0.012 15.3 1.8 0.71 9.5 0.0 2.8 2 2 1 3 3 3 0 Archaeal ATPase PPV_E1_C PF00519.12 CBZ23778.1 - 0.018 13.7 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_19 PF13245.1 CBZ23778.1 - 0.018 14.8 0.0 0.062 13.0 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain Viral_helicase1 PF01443.13 CBZ23778.1 - 0.02 14.3 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 CBZ23778.1 - 0.021 13.9 0.0 0.049 12.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.10 CBZ23778.1 - 0.03 14.1 0.0 0.18 11.6 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 CBZ23778.1 - 0.037 13.1 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.7 CBZ23778.1 - 0.047 13.3 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.12 CBZ23778.1 - 0.048 12.5 0.0 0.095 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 CBZ23778.1 - 0.071 12.3 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_21 PF13304.1 CBZ23778.1 - 0.082 12.8 0.9 2.8 7.7 0.0 2.7 2 1 1 3 3 2 0 AAA domain NACHT PF05729.7 CBZ23778.1 - 0.085 12.5 0.0 0.65 9.6 0.0 2.1 1 1 2 3 3 3 0 NACHT domain AFG1_ATPase PF03969.11 CBZ23778.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Pkinase PF00069.20 CBZ23779.1 - 1.1e-44 152.5 0.0 1.5e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23779.1 - 3.6e-35 121.2 0.0 4.5e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase zf-B_box PF00643.19 CBZ23779.1 - 0.0043 16.9 4.6 0.0043 16.9 3.2 3.9 3 1 0 3 3 3 1 B-box zinc finger APH PF01636.18 CBZ23779.1 - 0.0084 15.8 0.2 0.017 14.8 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBZ23779.1 - 0.0085 14.9 0.1 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CBZ23779.1 - 0.032 13.2 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBZ23779.1 - 0.16 11.5 0.1 0.36 10.3 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L13e PF01294.13 CBZ23781.1 - 1.5e-54 184.2 5.3 1.5e-54 184.2 3.7 1.4 1 1 0 1 1 1 1 Ribosomal protein L13e PTPS PF01242.14 CBZ23781.1 - 0.051 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Ribosomal_L13e PF01294.13 CBZ23782.1 - 1.5e-54 184.2 5.3 1.5e-54 184.2 3.7 1.4 1 1 0 1 1 1 1 Ribosomal protein L13e PTPS PF01242.14 CBZ23782.1 - 0.051 13.2 0.0 0.073 12.7 0.0 1.2 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase HSP20 PF00011.16 CBZ23783.1 - 3.4e-17 62.1 0.0 4.2e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family PapC_N PF13954.1 CBZ23783.1 - 0.01 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 PapC N-terminal domain PDEase_I PF00233.14 CBZ23784.1 - 1e-61 208.7 1.7 1.4e-61 208.2 1.2 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Acyltransferase PF01553.16 CBZ23787.1 - 6.6e-11 41.7 0.0 1.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase NIF PF03031.13 CBZ23788.1 - 2.2e-29 102.1 0.0 3.2e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.7 CBZ23788.1 - 0.00052 19.0 0.1 0.00074 18.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Kinesin PF00225.18 CBZ23789.1 - 6.6e-93 311.0 0.0 9.6e-93 310.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain C2 PF00168.25 CBZ23789.1 - 3e-05 23.7 0.1 0.0002 21.1 0.0 2.3 2 0 0 2 2 2 1 C2 domain Kinesin PF00225.18 CBZ23790.1 - 8.7e-93 310.6 0.0 1.1e-92 310.2 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Ribosomal_L39 PF00832.15 CBZ23791.1 - 2.3e-19 68.5 14.3 2.6e-19 68.3 9.9 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Methyltransf_FA PF12248.3 CBZ23791.1 - 0.081 12.9 0.0 0.089 12.8 0.0 1.1 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase Peptidase_M18 PF02127.10 CBZ23792.1 - 5.7e-156 519.3 0.0 6.5e-156 519.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CBZ23792.1 - 2.9e-09 36.0 0.1 2e-05 23.5 0.0 2.2 1 1 0 2 2 2 2 M42 glutamyl aminopeptidase COQ7 PF03232.8 CBZ23793.1 - 9.6e-62 207.4 0.3 1.1e-61 207.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 NAP PF00956.13 CBZ23794.1 - 5.5e-18 64.9 1.8 2.6e-17 62.7 0.0 1.9 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DUF948 PF06103.6 CBZ23795.1 - 0.28 11.0 1.7 0.85 9.5 0.0 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.20 CBZ23796.1 - 7.3e-54 182.6 0.0 1e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23796.1 - 8.2e-35 120.1 0.0 1.4e-34 119.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ23796.1 - 0.00019 21.2 0.0 0.14 11.8 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBZ23796.1 - 0.09 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ECH PF00378.15 CBZ23797.1 - 2.2e-69 233.2 1.0 2.8e-69 232.9 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CBZ23797.1 - 0.0022 17.8 0.0 0.026 14.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 ECH_C PF13766.1 CBZ23797.1 - 0.044 13.9 0.2 0.097 12.8 0.1 1.6 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region UCH PF00443.24 CBZ23798.1 - 3.2e-48 164.1 0.0 1.6e-47 161.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CBZ23798.1 - 9.2e-16 57.7 8.1 9.2e-16 57.7 5.6 3.7 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 CBZ23798.1 - 1.1e-14 54.5 0.0 4e-14 52.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 CBZ23798.1 - 3.2e-06 26.8 0.2 9.2e-06 25.3 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 CBZ23798.1 - 0.14 11.6 0.0 0.41 10.1 0.0 1.8 1 0 0 1 1 1 0 CUE domain Acyltransferase PF01553.16 CBZ23800.1 - 2.1e-09 36.9 0.0 3.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Sld5 PF05916.6 CBZ23802.1 - 3.6e-06 27.2 0.0 6.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Tropomyosin PF00261.15 CBZ23803.1 - 0.0073 15.4 2.2 0.0073 15.4 1.5 3.2 3 0 0 3 3 3 2 Tropomyosin MCC-bdg_PDZ PF10506.4 CBZ23803.1 - 0.014 15.2 0.2 0.014 15.2 0.1 4.2 5 1 0 5 5 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ADIP PF11559.3 CBZ23803.1 - 0.021 14.7 28.0 0.2 11.5 2.1 3.5 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Filament PF00038.16 CBZ23803.1 - 0.023 14.1 21.7 0.04 13.3 2.6 3.4 3 0 0 3 3 3 0 Intermediate filament protein DUF2067 PF09840.4 CBZ23803.1 - 0.032 13.7 1.1 0.11 11.9 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2067) Atg14 PF10186.4 CBZ23803.1 - 0.04 12.8 16.0 0.11 11.3 2.6 3.4 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4600 PF15372.1 CBZ23803.1 - 0.047 13.8 11.5 0.34 11.1 0.9 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF4600) ATG16 PF08614.6 CBZ23803.1 - 0.056 13.2 24.5 3.4 7.4 5.9 3.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.6 CBZ23803.1 - 0.59 10.5 12.5 5.2 7.5 0.5 4.4 4 0 0 4 4 4 0 Syntaxin 6, N-terminal BBP1_C PF15272.1 CBZ23803.1 - 0.66 9.4 13.6 0.056 12.9 0.6 3.1 3 0 0 3 3 3 0 Spindle pole body component BBP1, C-terminal Mnd1 PF03962.10 CBZ23803.1 - 0.78 9.3 19.0 0.88 9.1 2.6 3.4 3 0 0 3 3 3 0 Mnd1 family DUF4407 PF14362.1 CBZ23803.1 - 1.5 7.7 18.4 0.15 11.0 7.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HALZ PF02183.13 CBZ23803.1 - 1.6 8.4 13.7 4 7.2 0.0 4.6 5 0 0 5 5 5 0 Homeobox associated leucine zipper SPX PF03105.14 CBZ23803.1 - 2.5 7.7 6.4 5.1 6.7 4.4 1.4 1 0 0 1 1 1 0 SPX domain Fib_alpha PF08702.5 CBZ23803.1 - 3.8 7.6 10.0 1.6 8.8 0.4 3.3 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 CBZ23803.1 - 5.1 7.4 17.1 3.7 7.9 1.6 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Myosin_tail_1 PF01576.14 CBZ23803.1 - 5.5 4.5 26.8 12 3.4 13.4 3.1 2 1 0 2 2 2 0 Myosin tail TPR_MLP1_2 PF07926.7 CBZ23803.1 - 8 6.2 34.9 3 7.5 2.8 3.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.3 CBZ23803.1 - 8.7 5.6 29.8 0.049 12.9 6.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) IncA PF04156.9 CBZ23803.1 - 8.8 5.8 32.8 0.047 13.2 4.4 4.2 5 0 0 5 5 5 0 IncA protein Peptidase_M1 PF01433.15 CBZ23804.1 - 1.3e-93 314.1 0.0 1.8e-93 313.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CBZ23804.1 - 4.1e-20 72.2 0.0 5.4e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CBZ23804.1 - 7.4e-13 48.6 0.1 1.6e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily ApbA PF02558.11 CBZ23805.1 - 0.022 14.1 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 CBZ23805.1 - 0.025 14.3 0.3 0.21 11.3 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus LRR_9 PF14580.1 CBZ23807.1 - 4.5e-14 52.3 0.4 7.3e-14 51.7 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CBZ23807.1 - 5.2e-11 41.9 3.8 0.00018 21.0 0.1 3.8 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ23807.1 - 5.5e-07 29.2 5.6 1.1e-06 28.2 0.8 2.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 CBZ23807.1 - 0.00098 18.8 3.0 17 5.9 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 CBZ23807.1 - 0.002 18.0 4.5 2.1 8.6 0.1 4.1 3 1 1 4 4 4 1 Leucine Rich repeat Dynamin_M PF01031.15 CBZ23808.1 - 4.8e-92 307.9 0.5 1e-91 306.7 0.3 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CBZ23808.1 - 3e-51 173.5 0.3 2.6e-50 170.5 0.0 2.3 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 CBZ23808.1 - 5.3e-24 83.9 1.9 1.3e-23 82.6 0.5 2.3 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CBZ23808.1 - 0.00023 21.0 0.6 0.0022 17.9 0.2 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase p450 PF00067.17 CBZ23808.1 - 0.0098 14.4 0.6 0.019 13.5 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 FeoB_N PF02421.13 CBZ23808.1 - 0.017 14.3 0.2 3.7 6.8 0.0 2.8 2 0 0 2 2 2 0 Ferrous iron transport protein B cIII PF08134.6 CBZ23808.1 - 0.023 14.3 0.9 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 cIII protein family Miro PF08477.8 CBZ23808.1 - 0.028 14.9 0.0 0.069 13.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF1546 PF07571.8 CBZ23808.1 - 0.12 12.5 0.0 0.51 10.4 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) DUF4379 PF14311.1 CBZ23810.1 - 2.1e-40 136.3 15.8 2.8e-14 52.6 0.3 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF4379) Lar_restr_allev PF14354.1 CBZ23810.1 - 0.024 14.9 9.2 0.52 10.6 0.2 4.5 4 0 0 4 4 4 0 Restriction alleviation protein Lar Zn_Tnp_IS91 PF14319.1 CBZ23810.1 - 0.035 13.6 0.2 0.035 13.6 0.2 3.2 3 2 0 3 3 3 0 Transposase zinc-binding domain SprT-like PF10263.4 CBZ23810.1 - 0.13 11.9 4.1 8.8 5.9 0.1 3.2 3 0 0 3 3 3 0 SprT-like family DUF2072 PF09845.4 CBZ23810.1 - 1.7 8.5 7.4 0.13 12.1 0.6 2.4 2 1 0 3 3 3 0 Zn-ribbon containing protein (DUF2072) DTW PF03942.10 CBZ23811.1 - 3.3e-16 59.1 0.4 1.3e-15 57.2 0.2 2.0 1 1 0 1 1 1 1 DTW domain GDI PF00996.13 CBZ23812.1 - 2.4e-175 583.0 0.1 2.7e-175 582.8 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor YodL PF14191.1 CBZ23812.1 - 0.031 14.7 0.1 0.39 11.2 0.0 2.4 2 0 0 2 2 2 0 YodL-like Pkinase PF00069.20 CBZ23813.1 - 4.2e-41 140.8 0.0 7.5e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23813.1 - 2.9e-15 56.0 0.0 7.5e-15 54.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23813.1 - 0.14 11.0 0.0 0.78 8.6 0.0 2.0 2 0 0 2 2 2 0 Kinase-like ERG2_Sigma1R PF04622.7 CBZ23814.1 - 1.5e-69 233.5 0.6 1.8e-69 233.2 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein LRR_4 PF12799.2 CBZ23815.1 - 3.3e-12 45.7 16.2 0.0013 18.2 0.2 7.0 3 2 5 8 8 8 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ23815.1 - 2.9e-10 39.7 10.2 0.00018 21.2 0.9 4.9 2 2 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CBZ23815.1 - 9e-09 34.1 13.1 1.8 8.8 0.2 8.9 7 3 1 8 8 8 3 Leucine Rich Repeat LRR_7 PF13504.1 CBZ23815.1 - 1.1e-06 27.8 13.9 11 6.7 0.0 9.6 10 0 0 10 10 10 2 Leucine rich repeat LRR_6 PF13516.1 CBZ23815.1 - 2.3e-05 23.9 12.9 5.6 7.3 0.0 7.8 8 1 0 8 8 8 1 Leucine Rich repeat FNIP PF05725.7 CBZ23815.1 - 9.7e-05 22.2 6.0 0.32 10.9 0.1 4.7 5 0 0 5 5 5 2 FNIP Repeat Dynactin_p62 PF05502.8 CBZ23815.1 - 0.051 12.3 0.3 0.083 11.6 0.2 1.2 1 0 0 1 1 1 0 Dynactin p62 family VIT1 PF01988.14 CBZ23816.1 - 5.2e-14 52.2 14.9 5.3e-13 48.9 9.8 2.6 1 1 0 1 1 1 1 VIT family UDP-g_GGTase PF06427.6 CBZ23817.1 - 1.9e-63 213.5 0.1 6.4e-62 208.5 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 CBZ23817.1 - 1.5e-05 24.4 0.2 3e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 UCH_1 PF13423.1 CBZ23817.1 - 0.26 10.7 0.0 0.46 9.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF4139 PF13598.1 CBZ23818.1 - 3.6e-66 223.6 0.1 5.4e-66 223.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) AAA_12 PF13087.1 CBZ23819.1 - 3.5e-33 114.6 0.0 6.8e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBZ23819.1 - 1.2e-18 67.6 0.0 8.3e-18 64.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBZ23819.1 - 1.3e-08 34.6 0.8 0.0027 17.2 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CBZ23819.1 - 4.2e-05 23.2 0.3 0.00077 19.1 0.0 3.2 3 0 0 3 3 3 1 Part of AAA domain PhoH PF02562.11 CBZ23819.1 - 0.0026 17.0 0.0 0.13 11.5 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.1 CBZ23819.1 - 0.0042 17.2 0.5 0.46 10.6 0.0 3.6 4 0 0 4 4 4 1 AAA domain DUF2075 PF09848.4 CBZ23819.1 - 0.012 14.6 0.1 0.034 13.1 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 CBZ23819.1 - 0.013 15.0 0.9 4.5 6.7 0.0 3.2 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 CBZ23819.1 - 0.015 16.0 0.1 0.048 14.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain CSD PF00313.17 CBZ23819.1 - 0.28 10.9 0.1 0.63 9.8 0.1 1.6 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain adh_short PF00106.20 CBZ23820.1 - 4.5e-07 29.9 0.1 8.6e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Gpi1 PF05024.10 CBZ23825.1 - 3.2e-31 108.4 5.5 4.6e-21 75.3 3.1 2.4 2 0 0 2 2 2 2 N-acetylglucosaminyl transferase component (Gpi1) Pkinase PF00069.20 CBZ23826.1 - 1.4e-74 250.5 0.0 1.9e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23826.1 - 4.7e-40 137.2 0.0 6.8e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23826.1 - 2.1e-06 26.8 0.0 9.9e-06 24.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CBZ23826.1 - 8e-06 25.3 0.3 0.00024 20.4 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 CBZ23826.1 - 0.00042 19.4 0.0 0.00077 18.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ23826.1 - 0.00083 19.1 0.3 0.073 12.7 0.1 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBZ23826.1 - 0.12 11.8 0.1 0.47 9.9 0.1 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase PPR_2 PF13041.1 CBZ23827.1 - 4.3e-06 26.6 0.1 0.078 12.9 0.0 4.4 3 1 2 5 5 5 2 PPR repeat family PPR PF01535.15 CBZ23827.1 - 0.00014 21.5 0.0 3.3 7.8 0.0 4.4 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.1 CBZ23827.1 - 0.0012 18.9 5.3 29 5.2 0.0 6.1 6 1 0 6 6 6 1 Pentatricopeptide repeat domain BTAD PF03704.12 CBZ23827.1 - 0.032 14.5 5.5 0.32 11.2 1.2 3.6 3 1 0 3 3 3 0 Bacterial transcriptional activator domain Nol1_Nop2_Fmu PF01189.12 CBZ23828.1 - 1.9e-15 57.0 0.0 2e-05 24.1 0.0 3.6 4 0 0 4 4 4 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CBZ23828.1 - 0.00015 21.7 2.6 0.0015 18.5 0.2 3.2 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 CBZ23828.1 - 0.096 12.6 0.0 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase dCMP_cyt_deam_1 PF00383.17 CBZ23829.1 - 2.8 7.6 7.7 30 4.3 5.4 2.3 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region LcrG PF07216.7 CBZ23830.1 - 0.1 12.6 0.2 0.32 11.0 0.2 1.9 1 0 0 1 1 1 0 LcrG protein BatA PF07584.6 CBZ23831.1 - 1.4 9.1 6.2 2.1 8.5 2.9 2.5 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal Fumerase PF05681.9 CBZ23833.1 - 1.7e-40 138.8 0.0 2.1e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fer4_21 PF14697.1 CBZ23833.1 - 0.063 13.1 0.8 12 5.8 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain PPTA PF01239.17 CBZ23834.1 - 9.3e-19 65.9 20.7 1.9e-08 33.3 0.2 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat R3H-assoc PF13902.1 CBZ23834.1 - 0.27 11.2 1.9 0.87 9.5 0.0 2.7 3 0 0 3 3 3 0 R3H-associated N-terminal domain EF-hand_7 PF13499.1 CBZ23836.1 - 2.3e-08 34.0 0.0 0.6 10.2 0.0 4.1 3 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CBZ23836.1 - 0.00066 19.3 0.1 3.3 7.8 0.0 4.1 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 CBZ23836.1 - 0.0038 16.4 0.6 0.44 9.9 0.1 3.5 4 0 0 4 4 4 1 EF hand Zn_ribbon_recom PF13408.1 CBZ23839.1 - 0.035 14.3 0.4 0.071 13.3 0.2 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.1 CBZ23839.1 - 0.1 12.1 0.3 0.25 10.8 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DnaJ PF00226.26 CBZ23840.1 - 1.8e-08 34.0 0.0 3.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain zf-met2 PF12907.2 CBZ23842.1 - 0.00085 19.2 0.3 0.0021 18.0 0.2 1.7 1 1 0 1 1 1 1 Zinc-binding Lipase_3 PF01764.20 CBZ23843.1 - 0.11 12.0 0.0 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) PIH1 PF08190.7 CBZ23844.1 - 1.5e-11 44.3 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Rhabdo_ncap PF00945.13 CBZ23845.1 - 0.028 13.0 0.0 0.045 12.3 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein DUF2730 PF10805.3 CBZ23845.1 - 0.067 12.9 7.0 1.7 8.4 0.1 3.6 2 2 0 4 4 4 0 Protein of unknown function (DUF2730) XPG_N PF00752.12 CBZ23845.1 - 0.087 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 XPG N-terminal domain Snapin_Pallidin PF14712.1 CBZ23845.1 - 0.11 12.7 22.2 0.21 11.9 0.4 4.6 2 2 2 4 4 4 0 Snapin/Pallidin IncA PF04156.9 CBZ23845.1 - 0.23 11.0 30.4 0.13 11.8 4.3 2.4 2 0 0 2 2 2 0 IncA protein DUF1664 PF07889.7 CBZ23845.1 - 1.4 8.7 13.5 0.59 9.9 1.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 CBZ23845.1 - 1.8 6.8 12.7 1.2 7.4 0.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF342) Baculo_PEP_C PF04513.7 CBZ23845.1 - 2.1 8.1 11.9 0.11 12.3 0.2 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 CBZ23845.1 - 3.7 7.6 15.3 0.46 10.5 1.2 3.7 2 1 2 4 4 4 0 Proteins of 100 residues with WXG Bacillus_HBL PF05791.6 CBZ23845.1 - 4.8 6.5 13.0 0.11 11.8 2.0 2.6 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.5 CBZ23845.1 - 5.9 7.0 20.0 5.3 7.1 3.6 3.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Pyr_redox_2 PF07992.9 CBZ23846.1 - 5.3e-27 95.0 0.1 8.5e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ23846.1 - 1.6e-20 73.2 1.5 6.3e-17 61.7 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBZ23846.1 - 1.3e-19 70.1 0.0 3.6e-19 68.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.1 CBZ23846.1 - 1.9e-11 44.3 0.6 2e-09 37.8 0.1 2.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBZ23846.1 - 3.8e-10 39.4 0.1 8.5e-10 38.2 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CBZ23846.1 - 8.2e-07 27.8 1.4 0.00031 19.3 0.4 3.2 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.14 CBZ23846.1 - 1.3e-06 27.7 0.1 0.026 13.5 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain GIDA PF01134.17 CBZ23846.1 - 2.7e-06 26.5 2.1 0.012 14.4 0.2 3.3 4 0 0 4 4 4 2 Glucose inhibited division protein A K_oxygenase PF13434.1 CBZ23846.1 - 1.9e-05 23.7 0.0 0.00017 20.6 0.0 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 CBZ23846.1 - 3.2e-05 23.1 1.0 0.0037 16.4 0.1 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 CBZ23846.1 - 6.2e-05 22.0 8.1 0.0052 15.7 0.6 3.2 2 2 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBZ23846.1 - 0.00014 20.8 1.7 0.00014 20.8 1.2 2.9 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 CBZ23846.1 - 0.0005 20.0 5.4 0.022 14.7 0.7 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 CBZ23846.1 - 0.0013 18.5 0.0 0.0041 16.9 0.0 1.8 1 0 0 1 1 1 1 ThiF family 3HCDH_N PF02737.13 CBZ23846.1 - 0.0014 18.3 0.0 0.0028 17.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CBZ23846.1 - 0.0014 18.1 0.1 0.36 10.3 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 CBZ23846.1 - 0.005 16.0 0.0 0.03 13.4 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CBZ23846.1 - 0.12 12.4 2.0 0.86 9.7 0.1 2.7 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 CBZ23846.1 - 0.16 10.8 1.3 1.2 7.9 0.1 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein Bac_surface_Ag PF01103.18 CBZ23847.1 - 1e-18 67.9 0.5 1.4e-18 67.4 0.3 1.3 1 1 0 1 1 1 1 Surface antigen Folliculin PF11704.3 CBZ23848.1 - 5e-08 32.7 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Ribosomal_S8 PF00410.14 CBZ23849.1 - 2e-23 82.6 0.0 2.9e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 BRCT PF00533.21 CBZ23850.1 - 6.4e-11 42.2 0.0 0.0039 17.3 0.0 4.9 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBZ23850.1 - 9.7e-08 31.7 1.4 0.048 13.5 0.0 5.2 5 1 0 5 5 5 3 twin BRCT domain Diphthamide_syn PF01866.12 CBZ23851.1 - 5.7e-114 380.4 0.0 7e-114 380.1 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Flagellar_rod PF05149.7 CBZ23852.1 - 8.8e-105 350.0 29.3 8.8e-105 350.0 20.3 2.8 2 1 1 3 3 3 1 Paraflagellar rod protein DUF1120 PF06551.7 CBZ23852.1 - 0.13 12.5 1.0 0.38 11.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Flagellar_rod PF05149.7 CBZ23853.1 - 8.8e-105 350.0 29.3 8.8e-105 350.0 20.3 2.8 2 1 1 3 3 3 1 Paraflagellar rod protein DUF1120 PF06551.7 CBZ23853.1 - 0.14 12.5 1.0 0.38 11.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Histone PF00125.19 CBZ23854.1 - 2.4e-16 59.5 0.0 3.5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ23854.1 - 0.027 14.5 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBZ23855.1 - 2.4e-16 59.5 0.0 3.5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ23855.1 - 0.027 14.5 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBZ23856.1 - 2.4e-16 59.5 0.0 3.5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ23856.1 - 0.027 14.5 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MutS_V PF00488.16 CBZ23857.1 - 1.7e-24 86.5 0.0 1.2e-16 60.9 0.0 2.5 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.13 CBZ23857.1 - 1.6e-21 77.0 0.0 4.3e-21 75.6 0.0 1.7 1 1 0 1 1 1 1 MutS domain III AAA_29 PF13555.1 CBZ23857.1 - 0.0061 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 CBZ23857.1 - 0.28 10.3 0.0 0.53 9.4 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain MORN PF02493.15 CBZ23858.1 - 6.1e-46 151.4 105.9 1.4e-06 27.6 1.3 21.7 22 0 0 22 22 22 18 MORN repeat 4HBT PF03061.17 CBZ23859.1 - 1.4e-14 53.9 7.2 1.3e-09 38.0 0.5 2.9 3 0 0 3 3 3 2 Thioesterase superfamily 4HBT_2 PF13279.1 CBZ23859.1 - 0.0067 16.8 2.6 2.8 8.3 1.8 3.2 1 1 0 1 1 1 1 Thioesterase-like superfamily DUF3232 PF11554.3 CBZ23860.1 - 0.023 14.5 0.4 0.06 13.2 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3232) CENP-F_leu_zip PF10473.4 CBZ23860.1 - 0.1 12.4 3.4 0.18 11.6 2.3 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Thioredoxin PF00085.15 CBZ23861.1 - 2.3e-07 30.4 0.0 2.9e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin ABC_tran PF00005.22 CBZ23862.1 - 1e-26 93.8 0.0 1.8e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ23862.1 - 9.9e-10 38.8 0.4 5.1e-07 29.9 0.0 2.2 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBZ23862.1 - 0.00047 19.4 0.1 0.0022 17.2 0.1 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CBZ23862.1 - 0.0037 16.7 0.3 1.3 8.3 0.2 2.1 1 1 1 2 2 2 2 AAA-like domain SbcCD_C PF13558.1 CBZ23862.1 - 0.0083 16.0 0.7 0.074 12.9 0.2 2.5 2 1 0 2 2 1 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 CBZ23862.1 - 0.014 15.1 0.0 0.23 11.2 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 CBZ23862.1 - 0.02 14.3 0.0 0.41 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CBZ23862.1 - 0.022 13.9 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 CBZ23862.1 - 0.059 12.2 0.2 0.098 11.5 0.1 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein DUF770 PF05591.7 CBZ23862.1 - 0.077 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF770) AAA_29 PF13555.1 CBZ23862.1 - 0.085 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 CBZ23862.1 - 0.095 11.7 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 CBZ23862.1 - 0.096 11.9 0.1 1.4 8.0 0.0 2.5 3 0 0 3 3 3 0 PhoH-like protein NACHT PF05729.7 CBZ23862.1 - 0.099 12.3 0.9 0.34 10.5 0.1 2.1 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.12 CBZ23862.1 - 0.11 11.9 0.0 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 CBZ23862.1 - 0.16 12.8 0.1 0.31 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RINGv PF12906.2 CBZ23863.1 - 2.5e-11 43.4 10.0 2.7e-11 43.3 6.1 1.8 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 CBZ23863.1 - 0.00059 19.6 7.5 0.0014 18.3 5.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING-like PF08746.6 CBZ23863.1 - 0.46 10.5 6.5 0.82 9.7 4.5 1.4 1 0 0 1 1 1 0 RING-like domain dsrm PF00035.20 CBZ23864.1 - 1.2e-07 32.1 0.0 1.6 9.3 0.0 5.8 5 0 0 5 5 5 3 Double-stranded RNA binding motif SYS1 PF09801.4 CBZ23865.1 - 8.5e-21 74.4 1.6 2.3e-18 66.5 0.3 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network EMP70 PF02990.11 CBZ23867.1 - 6.4e-133 443.9 14.5 7.9e-133 443.6 10.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 XPC-binding PF09280.6 CBZ23870.1 - 8.5e-07 28.3 2.9 1.6e-06 27.4 2.0 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 CBZ23870.1 - 1e-05 25.1 0.0 3.5e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain DUF4404 PF14357.1 CBZ23870.1 - 2.5 8.5 6.5 3.6 8.0 1.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) CENP-B_dimeris PF09026.5 CBZ23870.1 - 2.6 8.3 16.3 3.1 8.1 4.3 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain WD40 PF00400.27 CBZ23871.1 - 8.3e-06 25.4 0.0 0.0083 15.9 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat Peptidase_M20 PF01546.23 CBZ23872.1 - 3.9e-36 124.3 0.1 5.1e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ23872.1 - 6e-19 67.8 0.0 1e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain RabGAP-TBC PF00566.13 CBZ23873.1 - 3.9e-43 147.4 0.0 5.4e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3135 PF11333.3 CBZ23873.1 - 0.039 14.0 1.9 0.067 13.3 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) MRF_C2 PF13888.1 CBZ23874.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 MFS_1 PF07690.11 CBZ23877.1 - 7.8e-17 61.0 34.7 1.2e-13 50.4 12.2 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CBZ23877.1 - 9.1e-13 48.0 22.3 9.9e-13 47.9 12.4 2.6 2 1 0 2 2 2 1 Nodulin-like DUF2371 PF10177.4 CBZ23877.1 - 0.3 10.9 1.3 5.4 6.8 0.1 3.5 3 2 1 4 4 4 0 Uncharacterised conserved protein (DUF2371) Nodulin-like PF06813.8 CBZ23878.1 - 1.2e-08 34.5 12.6 1.2e-08 34.5 8.7 3.1 3 1 0 3 3 3 1 Nodulin-like DUF819 PF05684.7 CBZ23878.1 - 0.0013 17.6 5.2 0.0048 15.7 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF819) Asn_synthase PF00733.16 CBZ23879.1 - 1.7e-35 122.7 0.1 4.7e-18 65.6 0.0 3.3 3 0 0 3 3 3 3 Asparagine synthase Ank_4 PF13637.1 CBZ23881.1 - 0.0007 20.0 0.5 0.0022 18.4 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBZ23881.1 - 0.0028 17.9 0.8 0.0056 16.9 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBZ23881.1 - 0.013 15.7 0.3 0.35 11.2 0.1 2.6 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.25 CBZ23881.1 - 0.013 15.2 4.4 1.8 8.5 0.1 3.4 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.1 CBZ23881.1 - 0.049 13.8 3.2 0.99 9.8 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeat PI3_PI4_kinase PF00454.22 CBZ23883.1 - 2.3e-31 109.0 0.0 4.5e-30 104.8 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CBZ23883.1 - 3.8e-16 58.8 0.3 1.7e-15 56.7 0.1 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) MIP-T3 PF10243.4 CBZ23883.1 - 0.68 8.3 2.9 1 7.7 2.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Clat_adaptor_s PF01217.15 CBZ23884.1 - 2.9e-45 153.4 1.0 3.5e-45 153.2 0.7 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-LYAR PF08790.6 CBZ23887.1 - 2.9e-14 52.4 2.5 2.9e-14 52.4 1.8 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Spo0A_C PF08769.6 CBZ23887.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal RRM_1 PF00076.17 CBZ23888.1 - 1.2e-20 72.8 0.3 8.5e-14 50.9 0.1 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23888.1 - 1.4e-16 60.1 0.3 1.6e-09 37.5 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Septum_form PF13845.1 CBZ23888.1 - 0.014 14.8 0.5 0.014 14.8 0.3 2.0 2 0 0 2 2 2 0 Septum formation RRM_5 PF13893.1 CBZ23888.1 - 0.05 13.4 0.2 3.5 7.5 0.1 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CBZ23888.1 - 0.065 13.2 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA binding domain RRM_1 PF00076.17 CBZ23890.1 - 4.3e-25 87.1 0.0 4.1e-14 51.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23890.1 - 8.1e-20 70.5 0.5 8.2e-10 38.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ23890.1 - 5.7e-07 29.2 0.0 5.6e-05 22.9 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ23891.1 - 2.7e-23 81.4 0.0 4.7e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23891.1 - 7.2e-14 51.5 0.0 5e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ23891.1 - 4.7e-07 29.5 0.0 6.3e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ23892.1 - 3.1e-23 81.1 0.0 9.4e-11 41.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23892.1 - 1.7e-14 53.5 0.0 9.1e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ23892.1 - 0.00021 21.0 0.0 0.01 15.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ23893.1 - 1.4e-32 111.1 0.0 7e-20 70.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23893.1 - 1.1e-24 86.1 0.0 1.8e-13 50.2 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ23893.1 - 3.4e-18 65.2 0.0 9.3e-12 44.6 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBZ23893.1 - 0.0088 15.7 0.3 0.061 13.0 0.0 2.4 3 0 0 3 3 3 1 Limkain b1 RRM_3 PF08777.6 CBZ23893.1 - 0.014 15.2 0.0 2.7 7.8 0.0 2.7 2 1 0 2 2 2 0 RNA binding motif Pkinase PF00069.20 CBZ23895.1 - 7.3e-60 202.3 0.0 2e-59 200.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23895.1 - 6e-33 114.0 0.0 8.4e-24 84.0 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 CBZ23895.1 - 0.0004 19.5 0.0 0.00073 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBZ23895.1 - 0.016 14.2 0.0 0.66 8.8 0.0 2.7 2 1 1 3 3 3 0 Kinase-like APH PF01636.18 CBZ23895.1 - 0.083 12.6 4.0 0.25 11.0 2.8 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family RNA_pol_Rpc34 PF05158.7 CBZ23896.1 - 4.9e-51 173.8 0.1 1.1e-49 169.3 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TFIIE_alpha PF02002.12 CBZ23896.1 - 0.014 14.8 0.0 0.03 13.8 0.0 1.6 1 1 0 1 1 1 0 TFIIE alpha subunit RPA_C PF08784.6 CBZ23896.1 - 0.34 11.3 1.6 1.1 9.7 0.2 2.5 2 2 0 2 2 2 0 Replication protein A C terminal Carn_acyltransf PF00755.15 CBZ23897.1 - 1.4e-88 297.5 0.0 1.6e-88 297.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Utp21 PF04192.7 CBZ23897.1 - 0.078 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain DUF4034 PF13226.1 CBZ23898.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4034) PRA-PH PF01503.12 CBZ23898.1 - 0.074 13.3 0.0 1.5 9.1 0.0 2.5 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DSS1_SEM1 PF05160.8 CBZ23899.1 - 0.00035 20.2 2.2 0.00035 20.2 1.5 1.8 2 0 0 2 2 2 1 DSS1/SEM1 family Lipase_3 PF01764.20 CBZ23900.1 - 3.2e-26 91.6 0.0 6.7e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) MIG-14_Wnt-bd PF06664.7 CBZ23900.1 - 2.5e-07 29.8 4.2 2.5e-07 29.8 2.9 2.2 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion DUF2304 PF10066.4 CBZ23900.1 - 1.5 8.7 4.2 0.63 9.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) AAA_2 PF07724.9 CBZ23901.1 - 1.6e-56 190.9 0.1 6.5e-54 182.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBZ23901.1 - 8e-28 97.2 0.0 1.8e-15 57.3 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CBZ23901.1 - 1.1e-20 73.2 0.1 1.1e-20 73.2 0.0 3.2 3 0 0 3 3 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CBZ23901.1 - 7.6e-15 54.8 0.5 2.5e-10 40.2 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 CBZ23901.1 - 1.3e-12 47.4 2.9 1e-05 25.3 0.9 3.1 2 0 0 2 2 2 2 Clp amino terminal domain AAA_16 PF13191.1 CBZ23901.1 - 6.5e-12 45.8 2.6 0.0013 18.7 0.0 4.5 3 2 2 5 5 4 2 AAA ATPase domain AAA_22 PF13401.1 CBZ23901.1 - 4e-10 39.9 0.9 0.00032 20.8 0.0 4.0 3 2 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 CBZ23901.1 - 3.5e-08 33.1 0.0 2.4e-05 23.8 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 CBZ23901.1 - 5.6e-08 32.7 0.0 0.0099 15.7 0.0 3.4 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 CBZ23901.1 - 2.1e-07 30.5 0.0 0.016 14.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 CBZ23901.1 - 2.3e-07 31.6 1.4 0.017 15.9 0.0 3.6 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CBZ23901.1 - 3.3e-06 26.3 1.0 0.0016 17.5 0.0 4.3 5 0 0 5 5 5 1 Zeta toxin NACHT PF05729.7 CBZ23901.1 - 9.6e-05 22.0 0.2 0.092 12.3 0.0 3.9 4 1 0 4 4 4 1 NACHT domain AAA_19 PF13245.1 CBZ23901.1 - 0.00011 21.9 0.2 0.11 12.2 0.0 3.2 2 1 1 3 3 3 1 Part of AAA domain AAA_18 PF13238.1 CBZ23901.1 - 0.00011 22.4 3.5 0.48 10.7 0.0 4.0 3 1 1 4 4 4 2 AAA domain RuvB_N PF05496.7 CBZ23901.1 - 0.00016 20.8 3.7 0.2 10.6 0.0 3.7 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CBZ23901.1 - 0.00033 20.1 2.5 1.2 8.5 0.0 4.4 3 1 1 4 4 4 1 AAA domain Arch_ATPase PF01637.13 CBZ23901.1 - 0.00036 20.3 8.7 0.9 9.1 0.0 4.5 3 3 2 5 5 5 1 Archaeal ATPase RNA_helicase PF00910.17 CBZ23901.1 - 0.0008 19.5 0.2 1.3 9.2 0.0 3.3 4 0 0 4 4 2 1 RNA helicase Mg_chelatase PF01078.16 CBZ23901.1 - 0.001 18.3 0.1 2.6 7.1 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CBZ23901.1 - 0.0012 18.6 0.1 0.56 10.0 0.0 3.7 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 CBZ23901.1 - 0.0014 17.3 0.1 0.2 10.3 0.0 3.0 2 1 1 3 3 3 1 TIP49 C-terminus AAA_3 PF07726.6 CBZ23901.1 - 0.0023 17.5 0.1 1.1 8.8 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CBZ23901.1 - 0.0029 17.4 0.0 0.2 11.4 0.0 3.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_29 PF13555.1 CBZ23901.1 - 0.0041 16.6 0.0 4 7.0 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBZ23901.1 - 0.0054 16.2 0.3 1.8 7.8 0.0 3.5 2 2 0 3 3 3 1 AAA-like domain DUF258 PF03193.11 CBZ23901.1 - 0.007 15.5 0.0 2.9 7.0 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CBZ23901.1 - 0.0073 16.0 0.4 3.2 7.4 0.0 3.5 3 0 0 3 3 3 1 NTPase ABC_tran PF00005.22 CBZ23901.1 - 0.016 15.4 1.8 11 6.2 0.0 3.9 4 1 0 4 4 3 0 ABC transporter AAA_28 PF13521.1 CBZ23901.1 - 0.021 14.8 0.0 9.6 6.1 0.0 3.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CBZ23901.1 - 0.03 14.2 0.1 0.88 9.5 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 CBZ23901.1 - 0.031 14.7 0.1 3.3 8.2 0.0 3.4 4 0 0 4 4 2 0 Miro-like protein AAA_23 PF13476.1 CBZ23901.1 - 0.041 14.2 16.6 9 6.5 0.0 3.9 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 CBZ23901.1 - 0.043 13.5 0.0 4.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 CBZ23901.1 - 0.047 13.3 0.1 14 5.2 0.0 2.9 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 Tetrabrachion PF11401.3 CBZ23901.1 - 0.066 13.0 0.6 0.5 10.1 0.0 2.5 2 0 0 2 2 2 0 Tetrabrachion DUF4524 PF15025.1 CBZ23901.1 - 0.089 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) DUF4140 PF13600.1 CBZ23901.1 - 0.64 10.4 11.2 16 5.9 0.0 4.4 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 CBZ23901.1 - 1.2 8.6 12.7 3.9 7.0 8.8 1.8 1 1 0 1 1 1 0 IncA protein APG6 PF04111.7 CBZ23901.1 - 2.9 6.8 9.8 5.5 5.9 6.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CBZ23901.1 - 7.1 4.3 7.1 11 3.6 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lipase_3 PF01764.20 CBZ23902.1 - 2.5e-27 95.2 0.0 1.8e-19 69.7 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_5 PF12695.2 CBZ23902.1 - 0.016 14.9 0.0 0.051 13.3 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 CBZ23902.1 - 0.02 14.2 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) HSP70 PF00012.15 CBZ23904.1 - 7.1e-27 93.5 3.2 2.2e-24 85.3 0.0 2.4 1 1 1 2 2 2 2 Hsp70 protein TPR_11 PF13414.1 CBZ23904.1 - 7.2e-15 54.3 4.7 1.7e-08 33.9 0.4 3.0 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBZ23904.1 - 2.2e-10 39.6 0.3 1.9e-06 27.2 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ23904.1 - 9.6e-09 34.5 1.1 2.4e-05 23.8 0.2 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ23904.1 - 7.3e-07 28.5 0.2 0.00034 20.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ23904.1 - 8.4e-06 25.5 0.3 0.00013 21.7 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ23904.1 - 1.2e-05 24.7 1.7 0.15 11.9 0.0 3.2 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ23904.1 - 1.5e-05 24.8 6.8 1.6e-05 24.7 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ23904.1 - 7.3e-05 23.0 2.6 0.00038 20.7 0.9 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ23904.1 - 0.00054 20.0 1.6 0.0013 18.7 1.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBZ23904.1 - 0.001 19.7 0.2 0.0083 16.7 0.1 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ23904.1 - 0.0027 17.7 0.1 0.012 15.7 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc5 PF12862.2 CBZ23904.1 - 0.0059 16.4 1.1 0.083 12.7 0.1 3.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.1 CBZ23904.1 - 0.01 16.3 0.5 0.01 16.3 0.4 3.0 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ23904.1 - 1.1 9.9 7.4 0.57 10.7 0.9 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Sec16_C PF12931.2 CBZ23905.1 - 1.1e-09 38.4 0.0 2.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 DUF572 PF04502.8 CBZ23906.1 - 1.3e-15 57.4 16.8 6.8e-15 55.1 11.7 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF4557 PF15101.1 CBZ23906.1 - 0.05 13.4 0.4 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) EI24 PF07264.6 CBZ23909.1 - 6.4e-09 35.5 22.4 7.4e-09 35.3 2.2 3.1 2 1 1 3 3 3 2 Etoposide-induced protein 2.4 (EI24) Thioredoxin_8 PF13905.1 CBZ23910.1 - 2.2e-05 24.4 0.0 0.26 11.4 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like EF-hand_7 PF13499.1 CBZ23911.1 - 1.1e-09 38.2 1.2 8.2e-05 22.6 0.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBZ23911.1 - 1.2e-05 24.8 0.1 4.7e-05 22.9 0.0 2.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ23911.1 - 3.6e-05 22.7 0.1 0.00015 20.8 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CBZ23911.1 - 0.00037 20.1 0.1 0.0013 18.4 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_9 PF14658.1 CBZ23911.1 - 0.02 14.7 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Thioredoxin_8 PF13905.1 CBZ23912.1 - 8.1e-25 86.7 0.0 1.1e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBZ23912.1 - 2.7e-08 33.5 0.0 4.7e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 CBZ23912.1 - 6.9e-08 32.6 0.0 9.4e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 CBZ23912.1 - 2.8e-07 30.1 0.0 3.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.15 CBZ23912.1 - 2.9e-07 30.1 0.1 2.9e-05 23.6 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 CBZ23912.1 - 0.00031 20.6 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 CBZ23912.1 - 0.00052 19.5 0.0 0.0011 18.4 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 CBZ23912.1 - 0.001 18.6 0.0 0.036 13.6 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin DUF953 PF06110.6 CBZ23912.1 - 0.059 12.8 0.1 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_8 PF13905.1 CBZ23913.1 - 1e-23 83.2 0.0 1.3e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBZ23913.1 - 5.6e-08 32.5 0.0 8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBZ23913.1 - 5.6e-08 32.4 0.0 5.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.15 CBZ23913.1 - 4.8e-06 26.1 0.0 4.2e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CBZ23913.1 - 2.3e-05 24.5 0.0 3.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 CBZ23913.1 - 3.8e-05 23.2 0.0 0.00019 21.0 0.0 1.8 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 CBZ23913.1 - 0.00082 19.3 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.6 CBZ23913.1 - 0.015 14.7 0.0 5.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 CBZ23913.1 - 0.025 14.1 0.0 0.093 12.2 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_8 PF13905.1 CBZ23914.1 - 8.5e-22 77.0 0.0 4.5e-17 61.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 CBZ23914.1 - 2.3e-12 46.6 0.0 4.2e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBZ23914.1 - 9.8e-12 44.6 0.0 2.3e-11 43.4 0.0 1.5 2 0 0 2 2 2 1 Redoxin Thioredoxin PF00085.15 CBZ23914.1 - 1.1e-07 31.5 0.0 3.4e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CBZ23914.1 - 1.8e-06 28.1 0.0 4.8e-06 26.7 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like domain TraF PF13728.1 CBZ23914.1 - 6.2e-05 22.5 0.0 9.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.1 CBZ23914.1 - 0.00013 21.9 0.0 0.00029 20.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CBZ23914.1 - 0.00017 21.1 0.0 0.00045 19.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin DUF4234 PF14018.1 CBZ23914.1 - 6.6 6.5 9.5 13 5.6 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Thioredoxin_8 PF13905.1 CBZ23915.1 - 2.7e-10 40.2 0.0 5.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBZ23915.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBZ23915.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_2 PF13098.1 CBZ23915.1 - 0.11 12.7 0.0 0.54 10.4 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain PSP1 PF04468.7 CBZ23916.1 - 8.9e-10 38.4 0.1 1.6e-09 37.5 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Ank_2 PF12796.2 CBZ23918.1 - 1.1e-31 108.9 1.1 5.5e-11 42.6 0.0 4.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ23918.1 - 4e-26 89.4 0.1 2.1e-05 24.0 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 CBZ23918.1 - 1.9e-25 88.7 0.3 1.2e-10 41.5 0.0 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ23918.1 - 5.9e-23 78.6 0.1 0.00074 19.5 0.0 6.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 CBZ23918.1 - 6e-19 67.6 0.8 6e-06 26.3 0.0 6.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) zf-HC2 PF13490.1 CBZ23918.1 - 0.037 13.9 0.4 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Putative zinc-finger Ribosomal_L4 PF00573.17 CBZ23919.1 - 3e-39 134.4 0.1 4.7e-39 133.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBZ23919.1 - 6.3e-15 54.8 7.8 8e-15 54.4 4.0 2.1 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L4 PF00573.17 CBZ23920.1 - 1.9e-39 135.0 0.1 3.1e-39 134.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CBZ23920.1 - 2.9e-15 55.9 7.3 4.3e-15 55.3 3.6 2.2 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ku PF02735.11 CBZ23922.1 - 1.7e-18 66.7 0.0 4.2e-18 65.4 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CBZ23922.1 - 1.4e-16 60.6 0.0 1e-10 41.4 0.0 2.8 3 0 0 3 3 3 2 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 CBZ23922.1 - 0.00054 20.4 0.3 0.65 10.5 0.1 2.4 2 0 0 2 2 2 2 Ku70/Ku80 C-terminal arm cNMP_binding PF00027.24 CBZ23923.1 - 2.1e-14 53.1 0.0 1.6e-09 37.4 0.0 3.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain EcoRII-N PF09217.5 CBZ23924.1 - 0.13 11.8 1.7 0.22 11.0 0.1 1.9 1 1 1 2 2 2 0 Restriction endonuclease EcoRII, N-terminal DUF4120 PF13496.1 CBZ23924.1 - 0.14 12.1 1.9 0.25 11.4 0.2 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4120) LMBR1 PF04791.11 CBZ23924.1 - 0.23 10.0 6.1 0.25 9.8 4.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Nexin_C PF08628.7 CBZ23924.1 - 1.1 9.3 5.9 0.25 11.4 0.4 2.3 1 1 1 2 2 2 0 Sorting nexin C terminal Band_3_cyto PF07565.8 CBZ23924.1 - 1.4 8.3 7.3 1.9 7.9 5.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Fumble PF03630.9 CBZ23924.1 - 1.9 7.2 5.8 6 5.6 1.3 2.1 1 1 1 2 2 2 0 Fumble PYC_OADA PF02436.13 CBZ23924.1 - 5.3 6.4 6.9 4.2 6.7 3.5 1.7 1 1 1 2 2 2 0 Conserved carboxylase domain Exonuc_VII_L PF02601.10 CBZ23924.1 - 5.8 6.0 9.7 6.5 5.8 6.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DltD_M PF04918.7 CBZ23924.1 - 9.6 6.3 8.5 10 6.3 4.8 1.8 1 1 1 2 2 2 0 DltD central region SseB PF07179.7 CBZ23925.1 - 4.2e-06 26.5 0.0 0.012 15.3 0.0 2.9 2 0 0 2 2 2 2 SseB protein N-terminal domain ADH_N PF08240.7 CBZ23926.1 - 4.1e-12 45.8 1.4 2.8e-11 43.1 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CBZ23926.1 - 5.3e-12 46.7 0.0 1.4e-11 45.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CBZ23926.1 - 4.8e-11 42.3 0.0 4.8e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Reo_sigmaC PF04582.7 CBZ23927.1 - 6.5e-05 22.2 3.6 0.2 10.8 0.7 3.0 3 0 0 3 3 3 2 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 CBZ23927.1 - 7.5e-05 22.5 7.2 0.09 12.5 1.4 2.9 3 1 1 4 4 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 CBZ23927.1 - 0.0019 16.9 2.5 0.0019 16.9 1.7 2.9 3 0 0 3 3 3 1 Spc7 kinetochore protein BLOC1_2 PF10046.4 CBZ23927.1 - 0.01 15.9 8.4 0.16 12.1 0.3 3.6 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG5 PF10392.4 CBZ23927.1 - 0.015 15.2 0.3 0.015 15.2 0.2 3.2 3 0 0 3 3 3 0 Golgi transport complex subunit 5 bZIP_2 PF07716.10 CBZ23927.1 - 0.051 13.4 0.5 0.051 13.4 0.3 5.4 6 1 0 6 6 5 0 Basic region leucine zipper Fib_alpha PF08702.5 CBZ23927.1 - 0.092 12.8 11.9 0.28 11.2 0.4 4.6 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family HALZ PF02183.13 CBZ23927.1 - 0.11 12.1 0.3 0.11 12.1 0.2 4.2 5 0 0 5 5 4 0 Homeobox associated leucine zipper GAS PF13851.1 CBZ23927.1 - 0.12 11.5 23.9 0.13 11.4 2.1 3.9 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Herpes_U30 PF04523.8 CBZ23927.1 - 0.18 9.2 7.0 0.011 13.2 0.4 2.1 3 0 0 3 3 3 0 Herpes virus tegument protein U30 DUF972 PF06156.8 CBZ23927.1 - 0.22 11.8 18.2 0.52 10.6 2.8 4.6 4 2 0 4 4 3 0 Protein of unknown function (DUF972) AAA_23 PF13476.1 CBZ23927.1 - 0.45 10.7 7.3 3.7 7.8 0.1 3.1 3 0 0 3 3 3 0 AAA domain LPP PF04728.8 CBZ23927.1 - 0.62 9.9 5.6 3.7 7.4 0.0 3.2 3 0 0 3 3 2 0 Lipoprotein leucine-zipper Acetyltransf_11 PF13720.1 CBZ23927.1 - 0.65 10.2 2.5 8.4 6.6 0.2 3.0 2 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 NPV_P10 PF05531.7 CBZ23927.1 - 1.1 9.5 6.8 4 7.7 0.5 3.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein AATF-Che1 PF13339.1 CBZ23927.1 - 1.1 9.3 18.6 0.51 10.4 1.5 4.0 3 1 0 4 4 4 0 Apoptosis antagonizing transcription factor TBPIP PF07106.8 CBZ23927.1 - 1.2 8.6 14.4 0.022 14.2 1.2 3.3 4 0 0 4 4 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GP20 PF06810.6 CBZ23927.1 - 1.8 7.9 12.5 0.35 10.2 2.6 3.1 3 0 0 3 3 3 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.3 CBZ23927.1 - 1.9 8.2 15.9 0.15 11.7 0.3 3.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.6 CBZ23927.1 - 2.2 8.7 10.9 0.44 10.9 0.9 3.4 3 2 0 3 3 3 0 Syntaxin 6, N-terminal DUF501 PF04417.7 CBZ23927.1 - 2.7 7.8 9.3 1.1 9.0 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF501) CCDC155 PF14662.1 CBZ23927.1 - 3.6 7.1 25.8 0.23 11.0 2.3 3.3 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 DUF2075 PF09848.4 CBZ23927.1 - 5.8 5.7 8.2 0.11 11.4 1.1 1.5 2 0 0 2 2 1 0 Uncharacterized conserved protein (DUF2075) DUF342 PF03961.8 CBZ23927.1 - 6 5.1 10.4 0.51 8.6 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF342) Syntaxin PF00804.20 CBZ23927.1 - 6.5 6.9 16.9 1.2 9.3 3.1 4.0 3 2 0 3 3 3 0 Syntaxin Seryl_tRNA_N PF02403.17 CBZ23927.1 - 8 6.5 21.5 0.18 11.8 1.2 4.7 3 2 1 5 5 5 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 CBZ23927.1 - 9.7 5.1 21.9 0.073 12.1 3.0 3.0 3 0 0 3 3 3 0 Autophagy protein Apg6 AA_synth PF06684.6 CBZ23928.1 - 0.0017 17.7 0.0 0.0054 16.1 0.0 1.8 1 0 0 1 1 1 1 Amino acid synthesis Kinesin PF00225.18 CBZ23930.1 - 2.8e-83 279.4 0.0 5e-82 275.2 0.0 2.9 2 0 0 2 2 2 1 Kinesin motor domain ZYG-11_interact PF05884.7 CBZ23930.1 - 6.8 5.6 4.0 24 3.8 2.8 2.1 1 0 0 1 1 1 0 Interactor of ZYG-11 FGE-sulfatase PF03781.11 CBZ23933.1 - 2.7e-22 79.3 0.9 5.8e-22 78.2 0.6 1.6 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Methyltransf_25 PF13649.1 CBZ23933.1 - 3.3e-17 62.7 0.0 8.5e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DinB_2 PF12867.2 CBZ23933.1 - 7.6e-06 26.2 0.0 1.8e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_18 PF12847.2 CBZ23933.1 - 2.9e-05 24.6 0.0 0.00013 22.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ23933.1 - 0.0002 21.0 0.0 0.00062 19.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ23933.1 - 0.00045 19.8 0.0 0.04 13.5 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ23933.1 - 0.022 15.2 0.0 0.092 13.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ23933.1 - 0.13 12.7 0.0 2.1 8.8 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain ABC2_membrane PF01061.19 CBZ23935.1 - 9.8e-06 24.8 19.0 1.7e-05 24.1 13.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBZ23935.1 - 0.0075 16.5 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter LETM1 PF07766.8 CBZ23936.1 - 4.8e-39 134.0 4.3 3.1e-30 105.1 0.1 2.9 3 0 0 3 3 3 2 LETM1-like protein Dpoe2NT PF12213.3 CBZ23936.1 - 0.04 13.8 0.5 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal FBP PF07299.6 CBZ23936.1 - 0.048 12.9 0.1 0.088 12.1 0.1 1.4 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) Peptidase_A22B PF04258.8 CBZ23937.1 - 6e-57 193.3 16.7 1.8e-55 188.5 8.7 2.1 1 1 1 2 2 2 2 Signal peptide peptidase DUF1119 PF06550.6 CBZ23937.1 - 0.057 12.5 14.2 0.3 10.1 9.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1119) IPPT PF01715.12 CBZ23938.1 - 6.7e-12 44.9 0.0 8.9e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.2 CBZ23938.1 - 0.0001 22.3 0.4 0.00017 21.6 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3449 PF11931.3 CBZ23938.1 - 0.028 13.9 0.3 0.049 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 CBZ23938.1 - 0.05 13.7 0.3 0.092 12.9 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF914 PF06027.7 CBZ23939.1 - 3.4e-63 213.5 26.5 4.5e-49 167.1 4.0 2.0 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 CBZ23939.1 - 6.9e-07 29.3 37.0 0.00018 21.5 8.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 CBZ23939.1 - 7e-05 22.5 23.3 0.014 15.0 2.9 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family PhyH PF05721.8 CBZ23940.1 - 3.8e-05 23.8 0.0 9.6e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) C1_1 PF00130.17 CBZ23940.1 - 0.00047 19.8 3.8 0.00047 19.8 2.6 2.2 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CBZ23940.1 - 0.0069 16.0 4.0 0.0069 16.0 2.8 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.24 CBZ23940.1 - 0.057 13.1 9.2 0.15 11.7 6.4 1.8 1 1 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 CBZ23940.1 - 2.2 8.1 11.9 3.1 7.7 7.3 2.0 1 1 0 1 1 1 0 Ring finger domain Arf PF00025.16 CBZ23941.1 - 8.6e-64 213.9 0.0 9.6e-64 213.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBZ23941.1 - 5.9e-15 54.9 0.0 7.1e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBZ23941.1 - 1.4e-14 53.8 0.0 1.6e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBZ23941.1 - 3.1e-12 45.8 0.3 2.8e-09 36.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBZ23941.1 - 3e-11 42.9 0.0 3.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBZ23941.1 - 2.9e-10 40.6 0.0 3.7e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBZ23941.1 - 2.5e-09 37.0 0.0 3.5e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBZ23941.1 - 4e-05 23.1 0.0 0.00037 19.9 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain cobW PF02492.14 CBZ23941.1 - 0.0029 17.0 0.0 0.064 12.6 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 CBZ23941.1 - 0.017 15.0 0.1 0.042 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 CBZ23941.1 - 0.057 13.1 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase PduV-EutP PF10662.4 CBZ23941.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 CBZ23941.1 - 0.063 14.1 0.0 0.095 13.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain PhdYeFM_antitox PF02604.14 CBZ23941.1 - 0.22 11.1 0.7 0.4 10.2 0.5 1.4 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system Cyt-b5 PF00173.23 CBZ23943.1 - 7e-09 35.3 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Amidohydro_1 PF01979.15 CBZ23944.1 - 9.3e-35 120.8 0.0 1.2e-34 120.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CBZ23944.1 - 5.6e-09 35.6 0.0 1.3e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 CBZ23944.1 - 2.1e-05 24.7 0.0 0.00022 21.3 0.0 2.6 2 1 0 2 2 2 1 Amidohydrolase RRM_5 PF13893.1 CBZ23945.1 - 7.9e-10 38.4 0.1 1.1e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23945.1 - 1.3e-08 34.6 0.0 1.7e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ23945.1 - 6.2e-07 28.9 0.0 9.8e-07 28.3 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG_box PF00505.14 CBZ23947.1 - 9.3e-34 115.5 11.1 3.7e-21 75.1 0.9 2.9 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CBZ23947.1 - 9.2e-24 83.6 16.8 1.4e-13 50.9 0.5 2.9 3 0 0 3 3 3 2 HMG-box domain DEK_C PF08766.6 CBZ23947.1 - 1.1e-07 31.4 0.0 1.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 DEK C terminal domain HMG_box_5 PF14887.1 CBZ23947.1 - 1.7e-06 27.7 15.7 6.2e-05 22.7 0.5 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box 5 DUF1074 PF06382.6 CBZ23947.1 - 0.00027 20.9 12.7 0.00061 19.8 1.9 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1074) PDCD9 PF07147.7 CBZ23947.1 - 0.00072 18.4 0.6 0.00086 18.1 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S30 (PDCD9) DUF736 PF05284.7 CBZ23947.1 - 0.0018 18.0 0.9 1.3 8.8 0.1 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF736) YABBY PF04690.8 CBZ23947.1 - 0.011 16.0 0.7 0.022 15.0 0.5 1.5 1 0 0 1 1 1 0 YABBY protein DUF2582 PF10771.4 CBZ23947.1 - 0.3 10.9 2.5 6.3 6.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2582) DUF1634 PF07843.6 CBZ23948.1 - 0.096 12.3 5.1 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) Peptidase_C1 PF00112.18 CBZ23950.1 - 2.1e-60 204.3 5.3 2.5e-60 204.0 3.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 CBZ23950.1 - 1.4e-05 23.8 1.5 0.0011 17.5 0.4 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.8 CBZ23950.1 - 0.031 13.9 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase family C1 propeptide DUF4203 PF13886.1 CBZ23951.1 - 0.03 13.7 0.3 0.051 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Phage_F PF02305.12 CBZ23953.1 - 0.015 13.8 0.0 0.034 12.6 0.0 1.5 2 0 0 2 2 2 0 Capsid protein (F protein) U-box PF04564.10 CBZ23955.1 - 3e-12 46.3 0.0 2.5e-11 43.3 0.0 2.5 3 0 0 3 3 3 1 U-box domain zf-Nse PF11789.3 CBZ23955.1 - 9.5e-06 25.0 0.0 2.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit VESA1_N PF12785.2 CBZ23955.1 - 0.048 12.6 0.1 5.1 5.9 0.0 2.1 2 0 0 2 2 2 0 Variant erythrocyte surface antigen-1 DUF3752 PF12572.3 CBZ23956.1 - 1.6 8.7 6.1 0.35 10.9 2.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) HSP90 PF00183.13 CBZ23957.1 - 1.9e-145 485.3 8.8 2.4e-145 484.9 6.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CBZ23957.1 - 2.5e-10 40.1 0.0 6.3e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ23957.1 - 8.7e-05 22.2 0.0 0.00023 20.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GSH-S_ATP PF02955.11 CBZ23957.1 - 0.02 14.0 0.1 0.26 10.4 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain Mpp10 PF04006.7 CBZ23958.1 - 1.8e-55 188.4 49.5 4.5e-54 183.8 34.3 2.9 1 1 0 1 1 1 1 Mpp10 protein WD40 PF00400.27 CBZ23959.1 - 9.8e-31 104.5 13.1 6e-06 25.9 0.0 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Apt1 PF10351.4 CBZ23960.1 - 0.11 11.3 2.3 0.16 10.7 1.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain EF_TS PF00889.14 CBZ23961.1 - 1.2e-17 63.9 0.0 3.7e-17 62.3 0.0 1.6 1 1 1 2 2 2 1 Elongation factor TS UBA PF00627.26 CBZ23961.1 - 0.0027 17.4 0.0 0.0061 16.3 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain FG-GAP PF01839.18 CBZ23962.1 - 0.00044 19.8 2.4 0.0088 15.7 1.2 2.7 2 0 0 2 2 2 1 FG-GAP repeat BBS2_Mid PF14783.1 CBZ23962.1 - 0.00064 19.4 0.2 0.55 10.0 0.1 2.5 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.1 CBZ23962.1 - 0.023 15.0 0.1 0.074 13.4 0.1 1.9 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_C PF14782.1 CBZ23962.1 - 0.03 12.8 0.3 0.19 10.2 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal CLAMP PF14769.1 CBZ23963.1 - 0.0016 18.5 0.0 0.49 10.5 0.0 2.5 2 0 0 2 2 2 2 Flagellar C1a complex subunit C1a-32 RRM_1 PF00076.17 CBZ23965.1 - 2.2e-21 75.2 0.0 1.5e-12 46.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23965.1 - 7.3e-17 61.1 0.0 8.8e-08 32.0 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ23965.1 - 1.6e-14 53.4 0.0 0.00037 20.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIE-A_C-term PF11521.3 CBZ23965.1 - 1.7 8.6 8.9 0.47 10.4 0.2 4.1 4 0 0 4 4 4 0 C-terminal general transcription factor TFIIE alpha Radial_spoke PF04712.7 CBZ23967.1 - 9.4e-144 479.8 0.0 1.2e-143 479.4 0.0 1.0 1 0 0 1 1 1 1 Radial spokehead-like protein PHO4 PF01384.15 CBZ23968.1 - 2.1e-24 85.8 0.0 2.1e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Phosphate transporter family DcpS_C PF11969.3 CBZ23969.1 - 3.8e-23 81.9 0.7 1.3e-22 80.1 0.7 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CBZ23969.1 - 7.8e-13 48.7 0.8 1.8e-12 47.6 0.2 1.8 2 0 0 2 2 2 1 HIT domain zf-C2H2_2 PF12756.2 CBZ23969.1 - 0.075 13.1 0.2 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) SNARE PF05739.14 CBZ23970.1 - 1.2e-07 31.2 1.6 1.8e-07 30.7 1.1 1.2 1 0 0 1 1 1 1 SNARE domain YukC PF10140.4 CBZ23970.1 - 0.0066 15.0 0.1 0.0086 14.6 0.1 1.3 1 1 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Treslin_N PF15292.1 CBZ23970.1 - 0.052 11.4 0.0 0.052 11.4 0.0 1.0 1 0 0 1 1 1 0 Treslin N-terminus DUF919 PF06034.6 CBZ23970.1 - 0.057 13.0 0.4 0.095 12.3 0.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF2976 PF11190.3 CBZ23970.1 - 0.15 11.5 0.4 0.3 10.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) ABC2_membrane_3 PF12698.2 CBZ23971.1 - 2.4e-55 187.9 55.5 3.9e-35 121.4 16.0 3.5 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.22 CBZ23971.1 - 1.7e-54 183.8 0.0 7.8e-27 94.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBZ23971.1 - 2.8e-12 47.1 1.0 0.00053 20.0 0.0 4.5 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 CBZ23971.1 - 4.8e-10 39.0 0.0 2.1e-05 23.8 0.1 3.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBZ23971.1 - 6.7e-06 25.5 1.4 0.0024 17.3 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CBZ23971.1 - 0.0014 18.9 0.4 0.29 11.4 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBZ23971.1 - 0.003 16.9 0.7 1.5 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBZ23971.1 - 0.004 16.3 0.3 0.52 9.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 CBZ23971.1 - 0.0076 16.1 0.0 1.8 8.5 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 CBZ23971.1 - 0.014 14.9 1.8 0.59 9.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBZ23971.1 - 0.069 13.3 0.0 5.2 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 CBZ23971.1 - 0.15 11.9 0.9 22 4.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 CBZ23971.1 - 0.63 10.2 2.5 3.9 7.6 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 CBZ23971.1 - 1.2 8.5 5.2 1.1 8.6 0.4 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 CBZ23971.1 - 3.3 6.0 0.9 17 3.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain zf-CCHC_2 PF13696.1 CBZ23972.1 - 5.5e-06 25.7 0.7 2e-05 23.9 0.5 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_jaz PF12171.3 CBZ23972.1 - 2.2e-05 24.4 1.1 6.4e-05 22.9 0.6 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding eIF3g PF12353.3 CBZ23972.1 - 0.0036 17.2 0.1 0.013 15.4 0.1 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-LITAF-like PF10601.4 CBZ23972.1 - 0.019 14.7 1.0 0.022 14.6 0.0 1.5 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain NUFIP1 PF10453.4 CBZ23972.1 - 0.027 13.9 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-C2H2_6 PF13912.1 CBZ23972.1 - 0.036 13.9 0.7 0.036 13.9 0.5 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 CBZ23972.1 - 0.056 13.6 0.3 0.15 12.3 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CBZ23972.1 - 0.079 13.3 0.2 0.079 13.3 0.1 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBZ23972.1 - 0.14 12.5 0.3 0.14 12.5 0.2 3.5 2 1 1 3 3 3 0 C2H2-type zinc finger zf-CCHC_5 PF14787.1 CBZ23972.1 - 0.2 11.1 6.7 0.027 13.9 1.2 2.0 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-NF-X1 PF01422.12 CBZ23973.1 - 3.3e-05 23.7 61.3 0.00014 21.7 8.3 14.5 14 2 1 15 15 15 5 NF-X1 type zinc finger ResIII PF04851.10 CBZ23974.1 - 6.5e-13 48.9 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBZ23974.1 - 1.9e-08 34.0 0.0 5.1e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.1 CBZ23974.1 - 7.5e-07 28.9 0.3 1.8e-06 27.7 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ23974.1 - 0.00037 20.0 0.1 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AF1Q PF15017.1 CBZ23975.1 - 0.016 15.0 0.1 0.087 12.7 0.0 2.1 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Ank_2 PF12796.2 CBZ23976.1 - 9.6e-11 41.8 0.1 2.8e-10 40.4 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ23976.1 - 9.8e-10 37.7 2.1 0.073 12.9 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 CBZ23976.1 - 1.5e-09 38.0 0.9 0.002 18.5 0.2 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ23976.1 - 5.7e-08 32.2 1.0 0.31 11.3 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CBZ23976.1 - 9.5e-06 25.6 2.0 0.064 13.5 0.2 3.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) RNase_T PF00929.19 CBZ23977.1 - 3.4e-24 85.9 0.0 5.3e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RNase_T PF00929.19 CBZ23979.1 - 5.2e-24 85.3 0.0 7.3e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease RNase_T PF00929.19 CBZ23980.1 - 7.6e-25 88.0 0.0 2.2e-22 80.0 0.0 2.2 1 1 0 1 1 1 1 Exonuclease LIN37 PF15306.1 CBZ23980.1 - 0.18 11.7 1.2 0.3 11.0 0.0 2.0 2 0 0 2 2 2 0 LIN37 Phage_int_SAM_2 PF12834.2 CBZ23980.1 - 0.39 11.1 1.6 0.43 11.0 0.2 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal Cofilin_ADF PF00241.15 CBZ23983.1 - 1.1e-31 109.3 0.2 1.2e-31 109.2 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CaATP_NAI PF12515.3 CBZ23984.1 - 1.9e-15 56.0 1.6 2.6e-15 55.6 0.1 2.1 2 0 0 2 2 2 1 Ca2+-ATPase N terminal autoinhibitory domain DUF3505 PF12013.3 CBZ23984.1 - 0.27 11.5 3.1 0.35 11.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) Gly-zipper_OmpA PF13436.1 CBZ23987.1 - 0.023 14.3 0.4 0.023 14.3 0.3 2.4 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 CBZ23987.1 - 0.091 12.4 11.3 0.037 13.6 5.7 1.9 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.10 CBZ23987.1 - 0.9 9.2 15.1 0.33 10.6 8.3 1.9 2 0 0 2 2 2 0 Glycine zipper 2TM domain Hydrolase_3 PF08282.7 CBZ23988.1 - 0.14 11.6 0.1 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Rad51 PF08423.6 CBZ23989.1 - 6.6e-13 48.1 0.8 2.4e-06 26.6 0.1 3.6 4 0 0 4 4 4 3 Rad51 RecA PF00154.16 CBZ23989.1 - 3.6e-08 32.8 2.5 1.1e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 CBZ23989.1 - 2.7e-07 29.9 0.0 4.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KaiC DUF2075 PF09848.4 CBZ23989.1 - 0.033 13.1 0.0 0.052 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 CBZ23989.1 - 0.058 12.7 6.8 1.5 8.1 1.2 2.8 3 1 0 3 3 3 0 AAA domain Metallophos PF00149.23 CBZ23990.1 - 0.0027 17.1 0.0 0.027 13.8 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBZ23990.1 - 0.0063 16.3 0.0 0.011 15.6 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PPR_3 PF13812.1 CBZ23991.1 - 5e-05 23.2 0.6 0.18 12.1 0.0 4.8 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 CBZ23991.1 - 0.016 15.2 0.0 0.099 12.6 0.0 2.4 2 1 0 2 2 2 0 PPR repeat family PPR_1 PF12854.2 CBZ23991.1 - 0.016 14.6 0.1 0.045 13.2 0.0 1.8 2 0 0 2 2 2 0 PPR repeat PPR PF01535.15 CBZ23991.1 - 0.058 13.3 0.0 11 6.2 0.0 3.3 3 0 0 3 3 3 0 PPR repeat zf-CCCH PF00642.19 CBZ23992.1 - 0.031 13.9 0.4 0.048 13.3 0.3 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RNA_pol_Rpb4 PF03874.11 CBZ23994.1 - 1e-05 25.5 0.0 3.3e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb4 Prolamin_like PF05617.6 CBZ23994.1 - 0.022 14.9 0.1 0.04 14.0 0.1 1.4 1 0 0 1 1 1 0 Prolamin-like Chlam_OMP3 PF03503.8 CBZ23994.1 - 0.079 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 RRM_1 PF00076.17 CBZ23995.1 - 2.4e-15 55.9 0.1 1.8e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ23995.1 - 1.1e-09 38.1 0.2 7.4e-05 22.6 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ23995.1 - 1.1e-06 28.3 0.3 0.00071 19.3 0.1 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ23995.1 - 0.022 14.5 0.2 0.86 9.4 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF3451 PF11933.3 CBZ23996.1 - 5.5e-37 127.7 1.5 1.3e-36 126.5 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3451) DUF3250 PF11618.3 CBZ23996.1 - 0.0069 16.5 0.0 0.0069 16.5 0.0 3.6 4 1 0 4 4 4 1 Protein of unknown function (DUF3250) Pkinase PF00069.20 CBZ23997.1 - 2.3e-40 138.3 0.0 9.7e-20 70.8 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ23997.1 - 8.5e-22 77.4 0.0 6.3e-13 48.3 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ23997.1 - 0.00021 20.3 0.0 0.23 10.3 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CBZ23997.1 - 0.0041 16.8 0.4 0.037 13.7 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBZ23997.1 - 0.012 14.3 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 CBZ23997.1 - 0.31 10.3 0.0 0.82 8.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 CBZ23997.1 - 0.35 9.9 0.0 0.66 9.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-met PF12874.2 CBZ23998.1 - 0.01 16.0 0.4 0.019 15.1 0.3 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CBZ23998.1 - 0.039 13.8 0.4 0.075 12.9 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger AKAP95 PF04988.7 CBZ23998.1 - 0.068 12.9 0.1 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) DUF766 PF05571.7 CBZ23999.1 - 0.15 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF766) UBA_4 PF14555.1 CBZ24000.1 - 1.5e-06 27.5 0.1 3.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 CBZ24000.1 - 0.0011 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like ArfGap PF01412.13 CBZ24001.1 - 1.8e-38 130.8 0.0 1.8e-38 130.8 0.0 1.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf RRN7 PF11781.3 CBZ24001.1 - 0.096 12.2 3.8 0.24 10.9 2.7 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 FGF-BP1 PF06473.7 CBZ24001.1 - 0.13 11.8 8.4 0.22 11.0 5.8 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) FAM176 PF14851.1 CBZ24001.1 - 1.1 8.9 5.6 33 4.1 3.4 2.3 2 0 0 2 2 2 0 FAM176 family TPR_11 PF13414.1 CBZ24002.1 - 1.3e-11 43.9 3.8 1e-08 34.7 1.6 2.7 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.1 CBZ24002.1 - 2.1e-05 24.3 0.9 0.1 12.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ24002.1 - 6.5e-05 22.3 0.9 0.025 14.1 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ24002.1 - 0.0001 22.1 0.4 0.0001 22.1 0.2 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ24002.1 - 0.00031 21.3 7.9 0.0051 17.4 0.9 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ24002.1 - 0.00098 18.8 13.3 1.3 9.1 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF2999 PF11212.3 CBZ24002.1 - 0.042 13.8 2.9 5.1 7.2 2.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2999) PAT1 PF09770.4 CBZ24002.1 - 0.058 11.6 8.5 0.086 11.0 5.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FHA PF00498.21 CBZ24003.1 - 4.9e-08 32.9 0.0 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 2 FHA domain zf-C2HC_2 PF13913.1 CBZ24004.1 - 3.7e-17 61.4 8.4 7.2e-11 41.4 1.3 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-FPG_IleRS PF06827.9 CBZ24004.1 - 0.0002 20.9 5.8 0.029 13.9 1.5 2.5 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS zf-C2H2 PF00096.21 CBZ24004.1 - 0.00032 20.8 3.6 0.081 13.2 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type TerY-C PF15616.1 CBZ24004.1 - 0.0012 18.8 0.7 0.06 13.2 0.0 2.7 3 0 0 3 3 3 1 TerY-C metal binding domain zf-Di19 PF05605.7 CBZ24004.1 - 0.0044 17.1 6.1 0.12 12.4 0.8 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Sgf11 PF08209.6 CBZ24004.1 - 0.0085 15.3 9.4 0.017 14.3 0.7 2.5 2 1 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zinc_ribbon_2 PF13240.1 CBZ24004.1 - 0.012 15.0 3.2 2.6 7.6 0.0 2.8 2 1 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 CBZ24004.1 - 0.017 15.4 1.2 3.3 8.1 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain DUF164 PF02591.10 CBZ24004.1 - 0.023 14.5 0.8 5 7.0 0.1 2.6 2 0 0 2 2 2 0 Putative zinc ribbon domain zf-ribbon_3 PF13248.1 CBZ24004.1 - 0.033 13.4 5.5 2.3 7.5 0.1 3.1 2 1 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.1 CBZ24004.1 - 0.039 14.2 3.2 1.3 9.3 1.1 2.9 2 1 1 3 3 3 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 CBZ24004.1 - 0.053 13.4 2.1 7.9 6.5 0.1 2.7 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.14 CBZ24004.1 - 0.057 13.1 1.2 8.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Amnionless PF14828.1 CBZ24004.1 - 0.063 11.7 0.0 0.095 11.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless zf-RING_3 PF14369.1 CBZ24004.1 - 0.065 13.2 5.4 3.6 7.6 0.3 2.8 3 0 0 3 3 2 0 zinc-finger zf-CHCC PF10276.4 CBZ24004.1 - 0.11 12.4 0.6 4.5 7.2 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger domain DZR PF12773.2 CBZ24004.1 - 0.13 12.1 1.9 11 5.9 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon Nairovirus_M PF07948.6 CBZ24004.1 - 0.19 9.7 3.8 0.75 7.8 0.2 2.0 2 0 0 2 2 2 0 Nairovirus M polyprotein-like Chorion_2 PF03964.10 CBZ24004.1 - 0.2 12.2 0.2 0.2 12.2 0.1 3.4 2 1 0 3 3 3 0 Chorion family 2 zf-C2H2_4 PF13894.1 CBZ24004.1 - 0.2 12.0 5.4 5.1 7.6 1.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Prok-RING_1 PF14446.1 CBZ24004.1 - 0.35 10.6 2.7 2.9 7.6 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF329 PF03884.9 CBZ24004.1 - 1.1 8.8 3.9 4 7.0 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF329) Zn_Tnp_IS1595 PF12760.2 CBZ24004.1 - 1.2 9.0 3.7 9.9 6.0 0.7 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.1 CBZ24004.1 - 9.5 6.3 6.9 26 4.9 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 FAD-oxidase_C PF02913.14 CBZ24005.1 - 5.1e-43 147.1 0.4 8.4e-43 146.4 0.3 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CBZ24005.1 - 5.3e-37 126.3 0.7 1.2e-36 125.2 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain CPSF_A PF03178.10 CBZ24005.1 - 0.15 11.0 0.0 0.41 9.6 0.0 1.6 2 0 0 2 2 2 0 CPSF A subunit region DUF605 PF04652.11 CBZ24006.1 - 0.76 9.1 29.8 0.91 8.8 20.7 1.0 1 0 0 1 1 1 0 Vta1 like TTL PF03133.10 CBZ24007.1 - 5.8e-43 146.8 0.0 4e-19 68.6 0.0 3.2 2 1 1 3 3 3 3 Tubulin-tyrosine ligase family HCV_NS5a_C PF12941.2 CBZ24007.1 - 0.062 12.8 2.7 2.9 7.3 0.5 2.3 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region ATP-grasp_4 PF13535.1 CBZ24007.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain DIOX_N PF14226.1 CBZ24008.1 - 2.4e-33 115.1 0.0 3.6e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CBZ24008.1 - 3.1e-24 85.1 0.0 5e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBZ24009.1 - 1e-33 116.3 0.0 1.7e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 CBZ24009.1 - 9e-25 86.8 0.0 1.6e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RIO1 PF01163.17 CBZ24010.1 - 2.6e-65 219.3 0.2 8.9e-65 217.5 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CBZ24010.1 - 0.016 14.9 0.1 0.13 11.9 0.1 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sigma70_ner PF04546.8 CBZ24010.1 - 2.3 7.8 11.0 4.9 6.7 7.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 CBZ24010.1 - 3.4 5.5 10.3 4.8 5.0 7.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Sec23_trunk PF04811.10 CBZ24012.1 - 2.8e-42 144.7 0.0 5e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CBZ24012.1 - 5e-21 75.0 0.0 1e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CBZ24012.1 - 3e-16 58.6 1.9 3e-16 58.6 1.3 2.0 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 CBZ24012.1 - 3.8e-08 32.6 0.0 8.4e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sen15 PF09631.5 CBZ24012.1 - 0.12 12.5 0.0 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 Sen15 protein DUF605 PF04652.11 CBZ24012.1 - 2.4 7.4 34.7 4.3 6.6 24.0 1.4 1 0 0 1 1 1 0 Vta1 like TPPII PF12580.3 CBZ24013.1 - 0.099 11.9 0.1 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II DUF217 PF02697.9 CBZ24013.1 - 1.5 9.0 4.2 1.6 9.0 0.0 2.9 2 1 1 3 3 3 0 Uncharacterized ACR, COG1753 DctQ PF04290.7 CBZ24013.1 - 2.4 7.9 11.3 9.2 6.0 6.1 2.1 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Remorin_C PF03763.8 CBZ24013.1 - 2.9 7.4 9.4 0.3 10.6 3.1 1.9 2 1 0 2 2 2 0 Remorin, C-terminal region SNF2_N PF00176.18 CBZ24014.1 - 9.3e-32 110.0 0.0 2.2e-31 108.8 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ24014.1 - 1.3e-06 28.1 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ24014.1 - 1.7e-05 24.6 0.0 0.031 14.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBZ24014.1 - 0.064 13.3 0.0 0.24 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 CBZ24014.1 - 0.087 12.3 0.2 0.82 9.1 0.1 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.4 CBZ24014.1 - 0.44 9.4 0.0 0.82 8.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pox_P4B PF03292.9 CBZ24015.1 - 0.14 10.0 1.3 0.2 9.5 0.9 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein DivIVA PF05103.8 CBZ24015.1 - 2 8.4 12.5 3.5 7.6 5.3 2.6 2 0 0 2 2 2 0 DivIVA protein zf-RanBP PF00641.13 CBZ24016.1 - 0.0037 16.3 7.9 0.0037 16.3 5.5 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 CBZ24016.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ24016.1 - 0.026 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IPP-2 PF04979.9 CBZ24017.1 - 9.5e-10 38.8 4.9 1.8e-09 37.9 3.4 1.4 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) TPR_19 PF14559.1 CBZ24019.1 - 4.3e-16 59.0 16.7 0.00085 19.6 0.3 6.2 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ24019.1 - 4.3e-16 58.3 21.7 2.2e-06 27.2 0.4 6.4 4 2 2 6 6 6 5 TPR repeat TPR_12 PF13424.1 CBZ24019.1 - 1.5e-13 50.4 13.9 0.00016 21.5 0.1 7.1 5 3 3 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ24019.1 - 4e-11 41.9 23.0 0.00033 20.3 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 CBZ24019.1 - 2.2e-10 40.5 21.1 1.1e-06 28.7 2.9 5.2 3 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CBZ24019.1 - 3.6e-10 40.2 17.6 7.8e-07 29.5 0.0 6.0 6 2 1 7 7 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ24019.1 - 1.4e-08 34.5 8.0 0.086 13.5 0.1 7.4 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ24019.1 - 1.7e-08 33.6 16.1 0.13 11.8 0.0 7.8 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ24019.1 - 3.2e-05 23.3 6.3 4.8 7.2 0.0 7.0 7 0 0 7 7 6 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 CBZ24019.1 - 0.0013 18.7 1.0 2.2 8.4 0.2 2.8 1 1 1 2 2 2 2 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_6 PF13174.1 CBZ24019.1 - 0.0015 18.8 24.8 0.31 11.5 0.0 8.3 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ24019.1 - 0.0027 17.6 11.5 5 7.1 0.1 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_3 PF07720.7 CBZ24019.1 - 0.0036 17.0 0.0 0.0036 17.0 0.0 3.9 6 0 0 6 6 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ24019.1 - 0.0065 16.2 4.2 0.099 12.5 0.4 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 CBZ24019.1 - 0.019 15.0 3.4 14 5.8 0.0 4.4 4 1 1 5 5 4 0 Tetratricopeptide repeat PPR PF01535.15 CBZ24019.1 - 0.024 14.5 6.9 16 5.7 0.1 4.9 5 0 0 5 5 4 0 PPR repeat HrpB1_HrpK PF09613.5 CBZ24019.1 - 0.14 11.6 2.7 0.23 10.9 0.0 2.7 3 1 0 3 3 2 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR_3 PF13812.1 CBZ24019.1 - 0.18 12.1 4.1 54 4.4 0.0 5.2 5 0 0 5 5 3 0 Pentatricopeptide repeat domain NARP1 PF12569.3 CBZ24019.1 - 0.2 10.3 12.9 0.11 11.2 0.5 3.4 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.1 CBZ24019.1 - 0.59 10.0 15.9 6.7 6.6 0.1 5.2 3 1 2 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 CBZ24019.1 - 1.1 9.2 15.4 16 5.5 0.0 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 CBZ24019.1 - 3.6 6.9 12.2 0.085 12.3 0.9 3.4 2 2 0 3 3 3 0 Foie gras liver health family 1 TPR_17 PF13431.1 CBZ24019.1 - 9.2 6.7 9.0 17 5.9 0.2 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat RNA_pol_A_bac PF01000.21 CBZ24020.1 - 1.5e-19 70.2 0.0 2.8e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CBZ24020.1 - 3.2e-14 51.7 0.0 4.4e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.1 CBZ24020.1 - 0.013 15.7 2.0 0.013 15.7 1.4 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBZ24020.1 - 0.047 14.0 1.2 0.047 14.0 0.8 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain IQ PF00612.22 CBZ24021.1 - 0.0015 18.0 2.0 0.0015 18.0 1.4 3.4 3 0 0 3 3 3 2 IQ calmodulin-binding motif PC_rep PF01851.17 CBZ24022.1 - 6.8e-23 79.5 17.0 3.1e-05 23.9 0.0 9.1 10 0 0 10 10 10 4 Proteasome/cyclosome repeat TipAS PF07739.8 CBZ24022.1 - 0.028 14.7 0.1 0.099 12.9 0.1 1.9 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain HEAT_EZ PF13513.1 CBZ24022.1 - 0.15 12.5 6.9 3.3 8.3 0.1 5.1 4 1 1 5 5 5 0 HEAT-like repeat DOCK-C2 PF14429.1 CBZ24023.1 - 1.3e-31 109.6 0.0 2.6e-31 108.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Fibrinogen_BP PF08017.6 CBZ24023.1 - 5.4e-09 34.7 109.2 5.4e-09 34.7 75.7 4.1 1 1 2 3 3 3 2 Fibrinogen binding protein WD40 PF00400.27 CBZ24024.1 - 9.7e-10 37.9 6.1 0.098 12.5 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat tify PF06200.9 CBZ24024.1 - 0.0011 18.1 0.2 1.3 8.3 0.1 2.6 2 0 0 2 2 2 2 tify domain Ras PF00071.17 CBZ24025.1 - 4.4e-35 120.4 0.2 5e-35 120.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ24025.1 - 4e-14 53.1 0.1 5.8e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ24025.1 - 9.5e-12 44.4 0.0 1.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ24025.1 - 1.9e-07 30.4 0.1 2.5e-07 30.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ24025.1 - 1.2e-05 24.7 0.1 5.3e-05 22.7 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CBZ24025.1 - 0.0024 17.3 0.0 0.092 12.2 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CBZ24025.1 - 0.0032 17.4 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CBZ24025.1 - 0.031 12.9 0.0 0.16 10.5 0.0 1.9 1 1 1 2 2 2 0 G-protein alpha subunit SNARE PF05739.14 CBZ24027.1 - 1.8e-12 46.7 6.1 1.8e-12 46.7 4.2 2.5 2 1 0 2 2 2 1 SNARE domain DUF4238 PF14022.1 CBZ24027.1 - 0.00044 19.6 0.9 0.00044 19.6 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4238) RmuC PF02646.11 CBZ24027.1 - 0.0074 15.1 2.0 0.0074 15.1 1.4 2.5 2 1 0 2 2 2 1 RmuC family Mac PF12464.3 CBZ24027.1 - 0.032 14.2 4.1 2.5 8.1 0.0 3.0 3 0 0 3 3 3 0 Maltose acetyltransferase DUF1664 PF07889.7 CBZ24027.1 - 0.045 13.5 4.9 0.71 9.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3708 PF12501.3 CBZ24027.1 - 0.078 12.8 1.4 0.21 11.3 0.2 2.1 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter Synaptobrevin PF00957.16 CBZ24027.1 - 0.2 11.2 6.4 0.085 12.4 1.5 2.2 2 0 0 2 2 2 0 Synaptobrevin Syntaxin-6_N PF09177.6 CBZ24027.1 - 0.76 10.2 10.0 2.3 8.6 1.1 2.8 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.1 CBZ24027.1 - 0.79 9.7 14.6 0.027 14.4 1.7 2.5 3 0 0 3 3 3 0 Syntaxin-like protein MCPsignal PF00015.16 CBZ24027.1 - 0.93 9.0 9.8 0.63 9.5 1.3 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain RhoGAP PF00620.22 CBZ24027.1 - 3.1 7.4 6.8 0.77 9.3 0.9 2.6 1 1 1 2 2 2 0 RhoGAP domain V_ATPase_I PF01496.14 CBZ24027.1 - 6.5 4.4 17.1 0.42 8.4 6.4 2.3 1 1 2 3 3 3 0 V-type ATPase 116kDa subunit family TMPIT PF07851.8 CBZ24027.1 - 8.4 5.3 8.0 1 8.3 0.4 2.2 2 1 0 2 2 2 0 TMPIT-like protein tRNA-synt_1b PF00579.20 CBZ24028.1 - 4.2e-21 75.3 0.0 1.8e-20 73.2 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_L3 PF00297.17 CBZ24031.1 - 6.7e-13 48.6 0.1 1.2e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_2 PF07719.12 CBZ24031.1 - 0.21 11.5 1.3 0.58 10.2 0.9 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat SPT16 PF08644.6 CBZ24032.1 - 7.1e-36 123.3 2.8 1.7e-35 122.1 0.0 2.3 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.7 CBZ24032.1 - 1.5e-15 56.8 0.1 1.7e-14 53.5 0.0 2.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 CBZ24032.1 - 9.5e-15 54.7 0.0 2.2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 Nop14 PF04147.7 CBZ24032.1 - 2.3 6.0 17.7 3.9 5.2 12.3 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CBZ24032.1 - 6.9 5.8 22.0 14 4.8 15.3 1.4 1 0 0 1 1 1 0 SDA1 ECH PF00378.15 CBZ24033.1 - 9e-40 136.3 0.0 1.2e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CLP_protease PF00574.18 CBZ24033.1 - 0.066 12.8 0.1 0.52 9.9 0.0 2.2 2 0 0 2 2 2 0 Clp protease SMC_N PF02463.14 CBZ24034.1 - 2.1e-62 210.2 1.4 3.1e-62 209.6 1.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBZ24034.1 - 1.6e-26 92.6 0.1 6.1e-26 90.7 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBZ24034.1 - 3.4e-15 56.7 0.1 3.6e-06 27.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CBZ24034.1 - 2.8e-07 31.0 33.6 2.8e-07 31.0 23.3 5.1 2 2 0 2 2 2 1 AAA domain AAA_15 PF13175.1 CBZ24034.1 - 5.4e-06 25.7 11.5 0.087 11.8 8.3 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CBZ24034.1 - 8.6e-05 21.9 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CBZ24034.1 - 0.41 10.9 25.3 0.27 11.5 0.1 6.0 4 3 0 4 4 4 0 ABC transporter MMR_HSR1 PF01926.18 CBZ24034.1 - 0.57 10.1 2.5 31 4.5 0.2 3.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase LsmAD PF06741.8 CBZ24034.1 - 1.7 8.8 10.9 2.1 8.5 1.9 3.9 2 0 0 2 2 2 0 LsmAD domain DASH_Dam1 PF08653.5 CBZ24034.1 - 2.3 8.0 4.9 70 3.2 0.0 3.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 Siva PF05458.7 CBZ24035.1 - 8.7 5.8 17.9 15 5.1 12.4 1.3 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Synaptobrevin PF00957.16 CBZ24036.1 - 3.9e-30 103.3 5.1 6.6e-30 102.5 3.5 1.4 1 0 0 1 1 1 1 Synaptobrevin EMP24_GP25L PF01105.19 CBZ24036.1 - 0.0064 16.2 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Longin PF13774.1 CBZ24036.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain LRR19-TM PF15176.1 CBZ24036.1 - 0.093 12.4 0.8 14 5.3 0.4 2.3 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF912 PF06024.7 CBZ24036.1 - 0.34 10.9 1.8 0.65 10.0 1.2 1.6 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Baculo_11_kDa PF06143.6 CBZ24036.1 - 1.7 8.0 7.2 3.6 7.0 4.7 1.7 1 1 0 1 1 1 0 Baculovirus 11 kDa family His_Phos_1 PF00300.17 CBZ24039.1 - 9.7e-31 106.9 0.0 1.1e-30 106.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ASCH PF04266.9 CBZ24040.1 - 1e-16 61.2 0.0 5.7e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 ASCH domain zf-C2HC5 PF06221.8 CBZ24040.1 - 1.6e-11 43.7 7.5 3.3e-11 42.7 5.2 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF4236 PF14020.1 CBZ24040.1 - 0.11 12.5 3.7 0.24 11.5 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) DEAD PF00270.24 CBZ24041.1 - 4.5e-34 117.3 0.0 7.4e-34 116.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ24041.1 - 1.4e-19 69.6 0.0 3.3e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ24041.1 - 0.00077 19.3 0.0 0.0036 17.1 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBZ24041.1 - 0.0011 19.1 0.0 0.0038 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain SNF2_N PF00176.18 CBZ24041.1 - 0.0068 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 CBZ24041.1 - 0.011 15.0 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain Adaptin_N PF01602.15 CBZ24042.1 - 2.6e-80 270.2 0.0 3.4e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CBZ24042.1 - 2e-05 24.7 2.3 0.13 12.5 0.2 4.0 2 2 2 4 4 4 2 HEAT repeats Cnd1 PF12717.2 CBZ24042.1 - 0.0028 17.5 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CBZ24042.1 - 0.015 15.3 9.4 1.3 9.2 0.1 5.3 4 0 0 4 4 4 0 HEAT repeat Vac14_Fab1_bd PF12755.2 CBZ24042.1 - 0.071 13.5 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 CBZ24042.1 - 0.083 12.7 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) Proteasom_PSMB PF10508.4 CBZ24042.1 - 0.15 10.2 0.9 0.44 8.7 0.1 1.8 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 CBZ24042.1 - 1.5 9.4 10.2 3.5 8.2 0.3 4.8 4 1 0 4 4 4 0 HEAT-like repeat DSPc PF00782.15 CBZ24043.1 - 2.3e-28 98.3 0.0 4.8e-28 97.3 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 CBZ24043.1 - 0.0021 17.4 0.1 1.3 8.3 0.0 2.9 3 0 0 3 3 3 2 Tyrosine phosphatase family Y_phosphatase PF00102.22 CBZ24043.1 - 0.025 13.9 0.1 0.049 12.9 0.0 1.5 2 0 0 2 2 2 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CBZ24043.1 - 0.036 14.1 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.7 CBZ24043.1 - 0.064 12.1 0.0 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase SCP-1 PF05483.7 CBZ24044.1 - 0.0021 15.9 7.0 0.0031 15.3 4.8 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) Phage_GP20 PF06810.6 CBZ24044.1 - 0.033 13.6 8.4 0.065 12.6 5.9 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 CENP-Q PF13094.1 CBZ24044.1 - 0.047 13.7 17.9 0.09 12.7 11.1 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TBPIP PF07106.8 CBZ24044.1 - 0.097 12.2 9.5 0.17 11.4 3.2 2.6 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 CBZ24044.1 - 0.13 11.8 19.2 0.71 9.4 11.9 2.9 2 1 0 2 2 2 0 IncA protein BLOC1_2 PF10046.4 CBZ24044.1 - 0.2 11.8 10.1 0.14 12.3 1.0 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT57 PF10498.4 CBZ24044.1 - 0.43 9.2 9.0 0.8 8.3 0.6 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.7 CBZ24044.1 - 0.55 10.0 9.3 1.9 8.3 1.4 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) COG2 PF06148.6 CBZ24044.1 - 1.6 8.6 10.4 0.38 10.6 0.2 3.3 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.8 CBZ24044.1 - 3.2 8.5 9.0 42 4.9 0.5 3.9 2 1 2 4 4 4 0 Occludin homology domain DUF342 PF03961.8 CBZ24044.1 - 3.7 5.8 5.4 4.4 5.5 3.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 CBZ24044.1 - 5.2 7.4 13.5 13 6.2 0.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) GAS PF13851.1 CBZ24044.1 - 5.4 6.1 14.4 3.7 6.7 6.7 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.8 CBZ24044.1 - 7.1 6.6 16.4 10 6.1 5.3 3.6 2 1 2 4 4 4 0 DivIVA protein FYVE_2 PF02318.11 CBZ24046.1 - 0.0014 18.5 3.5 0.0025 17.6 2.4 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger EF-hand_6 PF13405.1 CBZ24047.1 - 0.0056 16.4 0.3 0.028 14.2 0.0 2.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 CBZ24047.1 - 0.22 11.6 0.0 1.1 9.3 0.0 2.1 3 0 0 3 3 3 0 EF-hand domain pair ERCC4 PF02732.10 CBZ24048.1 - 6.2e-15 55.2 0.0 3.4e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain PIG-H PF10181.4 CBZ24049.1 - 2.9e-15 55.6 0.1 4.5e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component LRR_8 PF13855.1 CBZ24051.1 - 6e-11 41.9 0.8 0.02 14.6 0.0 5.3 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 CBZ24051.1 - 2.5e-09 36.5 0.2 0.00022 20.7 0.0 5.2 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBZ24051.1 - 0.061 13.5 14.3 1.7 9.1 0.0 6.5 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 CBZ24051.1 - 0.092 12.8 4.1 13 6.2 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.28 CBZ24051.1 - 0.14 12.2 14.3 2.8 8.3 0.1 6.7 7 3 0 7 7 7 0 Leucine Rich Repeat Hexapep PF00132.19 CBZ24052.1 - 1.7e-14 52.5 5.7 7.3e-06 25.2 0.0 3.4 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBZ24052.1 - 0.53 9.8 9.3 6.5 6.4 0.0 3.2 2 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Exo_endo_phos PF03372.18 CBZ24054.1 - 2.1e-16 60.6 0.0 3.1e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBZ24054.1 - 0.01 15.4 0.0 0.041 13.5 0.0 2.0 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase TOMM6 PF15184.1 CBZ24054.1 - 0.35 10.2 2.8 0.37 10.1 0.1 2.5 3 0 0 3 3 3 0 Mitochondrial import receptor subunit TOM6 homolog ThiF PF00899.16 CBZ24056.1 - 2.5e-31 108.2 0.2 1.4e-30 105.8 0.2 2.2 1 1 0 1 1 1 1 ThiF family UAE_UbL PF14732.1 CBZ24056.1 - 5.2e-23 80.9 0.0 8.8e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBACT PF02134.16 CBZ24056.1 - 1.8e-21 75.4 0.4 4.7e-21 74.1 0.3 1.8 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CBZ24056.1 - 7.1e-16 57.3 2.0 1.5e-15 56.2 1.4 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CBZ24056.1 - 0.006 16.6 0.0 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ABC1 PF03109.11 CBZ24057.1 - 1.3e-27 96.0 0.0 5e-27 94.2 0.0 2.0 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 CBZ24057.1 - 0.00014 21.7 2.8 0.00046 20.0 0.4 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 CBZ24057.1 - 0.11 11.5 0.1 0.52 9.3 0.0 1.9 2 0 0 2 2 2 0 Ecdysteroid kinase Ribosomal_L9_N PF01281.14 CBZ24058.1 - 5.7e-06 25.4 0.0 1.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Endothelin PF00322.12 CBZ24059.1 - 0.18 11.0 1.1 0.32 10.2 0.8 1.4 1 0 0 1 1 1 0 Endothelin family DUF4591 PF15261.1 CBZ24060.1 - 3.9e-05 23.9 10.1 0.0011 19.2 0.0 3.7 2 2 1 3 3 3 2 Domain of unknown function (DUF4591) Ribosomal_L2_C PF03947.13 CBZ24062.1 - 6.9e-19 67.9 0.1 1.1e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Sod_Fe_C PF02777.13 CBZ24063.1 - 1.6e-37 127.5 0.3 2.9e-37 126.7 0.0 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBZ24063.1 - 5.3e-19 68.2 0.0 1.3e-18 67.0 0.0 1.7 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Isochorismatase PF00857.15 CBZ24064.1 - 7.9e-15 55.2 0.0 4.1e-14 52.8 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.15 CBZ24065.1 - 1.3e-11 44.7 0.3 3.1e-11 43.5 0.2 1.6 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.15 CBZ24066.1 - 1.2e-12 48.1 0.3 5.8e-12 45.8 0.2 1.8 1 1 0 1 1 1 1 Isochorismatase family zf-Tim10_DDP PF02953.10 CBZ24067.1 - 8.5e-18 63.4 0.1 1.1e-17 63.0 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CBZ24067.1 - 0.0044 16.4 0.2 0.0065 15.9 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Defensin_big PF14862.1 CBZ24070.1 - 0.028 14.4 0.8 0.18 11.8 0.0 2.6 2 0 0 2 2 2 0 Big defensin FWWh PF14922.1 CBZ24072.1 - 0.00064 19.2 0.5 0.005 16.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function APG6 PF04111.7 CBZ24074.1 - 1.3e-15 57.2 0.0 1.7e-05 24.0 0.0 4.2 4 0 0 4 4 4 4 Autophagy protein Apg6 WD40 PF00400.27 CBZ24075.1 - 8.6e-34 114.2 27.6 3.2e-10 39.4 0.0 10.7 11 0 0 11 11 11 7 WD domain, G-beta repeat PQQ_2 PF13360.1 CBZ24075.1 - 9.7e-06 25.2 3.1 0.00026 20.5 0.4 4.0 2 2 1 3 3 3 2 PQQ-like domain BBS2_Mid PF14783.1 CBZ24075.1 - 0.00052 19.7 0.3 3.1 7.6 0.0 5.0 4 3 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 CBZ24075.1 - 0.0097 15.6 0.0 5.6 6.6 0.0 3.5 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Linker_histone PF00538.14 CBZ24077.1 - 0.00025 21.0 0.4 0.0033 17.4 0.1 2.7 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF4552 PF15089.1 CBZ24078.1 - 2.5 6.8 5.0 4.9 5.9 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) Peptidase_S24 PF00717.18 CBZ24079.1 - 3.5e-11 42.5 0.0 6.9e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like ABA_GPCR PF12430.3 CBZ24079.1 - 0.047 12.8 0.2 0.67 9.0 0.0 2.0 2 0 0 2 2 2 0 Abscisic acid G-protein coupled receptor Rad60-SLD PF11976.3 CBZ24081.1 - 9.7e-25 86.0 0.1 1.2e-24 85.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBZ24081.1 - 2.5e-08 33.2 0.0 3.1e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family DUF4407 PF14362.1 CBZ24082.1 - 0.06 12.3 0.5 0.082 11.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IZUMO PF15005.1 CBZ24082.1 - 0.13 12.2 0.1 0.71 9.9 0.0 2.0 1 1 0 2 2 2 0 Izumo sperm-egg fusion TMEM247 PF15444.1 CBZ24082.1 - 2.9 7.6 6.4 5.9 6.6 1.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 247 Fz PF01392.17 CBZ24083.1 - 0.03 14.6 0.1 0.053 13.8 0.1 1.3 1 0 0 1 1 1 0 Fz domain Pribosyl_synth PF14572.1 CBZ24085.1 - 4.6e-21 75.4 4.0 5.5e-21 75.1 0.3 2.6 3 0 0 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CBZ24085.1 - 6.3e-19 67.8 1.4 2.6e-17 62.6 0.0 2.9 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase SPX PF03105.14 CBZ24085.1 - 0.00016 21.5 3.4 0.0011 18.8 0.6 2.4 1 1 0 2 2 2 1 SPX domain Pribosyltran PF00156.22 CBZ24085.1 - 0.038 13.7 0.0 0.36 10.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Pkinase PF00069.20 CBZ24086.1 - 4.7e-07 29.2 0.0 0.0078 15.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24086.1 - 2.2e-06 26.9 0.0 0.0033 16.5 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kelch_1 PF01344.20 CBZ24086.1 - 0.011 15.2 0.0 2.1 7.9 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Pkinase PF00069.20 CBZ24087.1 - 5.2e-39 133.9 0.0 5.6e-27 94.5 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24087.1 - 4.1e-16 58.8 0.0 5.5e-06 25.6 0.0 3.4 3 1 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 CBZ24087.1 - 0.0033 17.1 0.1 0.01 15.5 0.1 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2312 PF10073.4 CBZ24087.1 - 0.62 9.4 0.0 1.1 8.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Complex1_LYR PF05347.10 CBZ24088.1 - 0.00032 20.4 0.5 0.0067 16.1 0.6 2.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBZ24088.1 - 0.011 15.8 0.7 0.011 15.8 0.5 1.9 2 0 0 2 2 2 0 Complex1_LYR-like CMAS PF02353.15 CBZ24089.1 - 3.1e-76 256.0 0.0 4.2e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CBZ24089.1 - 1.2e-12 47.8 0.0 2.3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ24089.1 - 8.2e-11 42.2 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ24089.1 - 2.7e-10 40.5 0.0 5.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ24089.1 - 3e-09 37.2 0.0 9.6e-09 35.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ24089.1 - 1.8e-08 34.9 0.0 4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ24089.1 - 4.9e-07 29.4 0.0 9.3e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ24089.1 - 2.6e-06 26.9 0.0 7.9e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBZ24089.1 - 2.7e-05 24.1 0.0 0.00021 21.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 CBZ24089.1 - 0.0012 18.3 0.0 0.0037 16.6 0.0 1.8 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW PCMT PF01135.14 CBZ24089.1 - 0.0033 16.9 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 CBZ24089.1 - 0.004 16.3 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 CBZ24089.1 - 0.006 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CBZ24089.1 - 0.0077 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 CBZ24089.1 - 0.0078 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.14 CBZ24089.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase eIF-5_eIF-2B PF01873.12 CBZ24090.1 - 4e-24 84.6 0.8 6.8e-24 83.9 0.5 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TFIIA PF03153.8 CBZ24090.1 - 0.33 10.7 11.1 0.42 10.4 7.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAPA-1 PF04795.7 CBZ24090.1 - 0.75 10.5 8.7 0.39 11.4 1.4 2.6 2 0 0 2 2 2 0 PAPA-1-like conserved region Cytochrom_c3_2 PF14537.1 CBZ24090.1 - 1.3 9.4 5.1 0.26 11.6 0.2 2.3 4 0 0 4 4 4 0 Cytochrome c3 CDC37_N PF03234.9 CBZ24090.1 - 2.2 8.5 8.2 0.11 12.7 1.7 1.9 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding Img2 PF05046.9 CBZ24091.1 - 0.00038 20.6 0.0 0.00069 19.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ASFV_J13L PF05568.6 CBZ24093.1 - 0.0018 17.8 0.2 0.0024 17.4 0.2 1.2 1 0 0 1 1 1 1 African swine fever virus J13L protein FtsX PF02687.16 CBZ24095.1 - 0.012 15.3 1.6 0.019 14.6 1.1 1.3 1 0 0 1 1 1 0 FtsX-like permease family 7tm_1 PF00001.16 CBZ24095.1 - 0.013 14.6 0.1 0.017 14.2 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) MFS_2 PF13347.1 CBZ24095.1 - 0.016 13.6 0.2 0.02 13.3 0.1 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein DUF2208 PF09973.4 CBZ24095.1 - 0.017 14.4 0.1 0.022 13.9 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Prominin PF05478.6 CBZ24095.1 - 0.028 11.9 0.1 0.033 11.7 0.0 1.0 1 0 0 1 1 1 0 Prominin YMF19 PF02326.10 CBZ24095.1 - 0.034 14.7 0.0 0.045 14.3 0.0 1.3 1 0 0 1 1 1 0 Plant ATP synthase F0 DUF1049 PF06305.6 CBZ24095.1 - 0.037 13.4 1.8 0.082 12.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) OATP PF03137.15 CBZ24095.1 - 0.048 11.7 0.0 0.058 11.4 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family WBP-1 PF11669.3 CBZ24095.1 - 0.059 13.4 0.1 0.079 13.0 0.0 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 UPF0370 PF13980.1 CBZ24095.1 - 0.084 12.7 0.3 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Tmemb_9 PF05434.6 CBZ24095.1 - 0.086 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 TMEM9 DUF4131 PF13567.1 CBZ24095.1 - 0.1 11.9 1.1 0.15 11.4 0.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Spore_YhaL PF14147.1 CBZ24095.1 - 0.35 10.3 1.9 0.53 9.7 1.3 1.2 1 0 0 1 1 1 0 Sporulation protein YhaL DUF1469 PF07332.6 CBZ24095.1 - 0.91 9.2 6.5 25 4.6 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) Amastin PF07344.6 CBZ24098.1 - 4.4e-06 26.3 7.0 8.8e-06 25.4 4.8 1.5 1 0 0 1 1 1 1 Amastin surface glycoprotein DnaJ PF00226.26 CBZ24099.1 - 1.4e-17 63.1 0.3 2e-17 62.6 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 CBZ24100.1 - 7.4e-19 67.8 0.0 1.6e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24100.1 - 1.2e-12 47.4 0.0 2.7e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CBZ24100.1 - 0.0092 14.8 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 HAMP PF00672.20 CBZ24100.1 - 0.35 11.0 3.0 1.5 9.0 2.1 2.2 1 1 0 1 1 1 0 HAMP domain AAA_16 PF13191.1 CBZ24101.1 - 6.1e-07 29.5 0.1 2.1e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 CBZ24101.1 - 7.9e-05 22.4 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 CBZ24101.1 - 0.0017 18.4 0.0 0.0057 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBZ24101.1 - 0.0018 18.1 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 CBZ24101.1 - 0.008 15.7 0.9 0.0099 15.4 0.0 1.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Miro PF08477.8 CBZ24101.1 - 0.021 15.2 0.0 0.043 14.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein DUF815 PF05673.8 CBZ24101.1 - 0.022 13.6 0.0 0.057 12.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) Adeno_IVa2 PF02456.10 CBZ24101.1 - 0.086 11.4 0.0 0.17 10.4 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein SMC_N PF02463.14 CBZ24101.1 - 0.16 11.1 0.0 3.2 6.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBZ24102.1 - 4.3e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 CBZ24102.1 - 0.0092 15.6 0.0 0.026 14.2 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 CBZ24102.1 - 0.015 14.4 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 CBZ24102.1 - 0.019 15.0 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ub-Mut7C PF14451.1 CBZ24102.1 - 0.036 13.5 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Mut7-C ubiquitin AAA_14 PF13173.1 CBZ24102.1 - 0.037 13.9 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CBZ24102.1 - 0.042 12.9 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC Amastin PF07344.6 CBZ24104.1 - 5.3e-52 175.5 15.9 6.4e-52 175.2 11.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ24104.1 - 1.9 8.1 18.7 0.051 13.2 8.1 1.8 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MMPL PF03176.10 CBZ24104.1 - 5.5 5.5 6.3 9.5 4.8 4.4 1.3 1 0 0 1 1 1 0 MMPL family Amastin PF07344.6 CBZ24105.1 - 4.1e-43 146.6 7.9 5e-43 146.3 5.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ24105.1 - 0.33 10.6 13.5 0.48 10.0 9.3 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Adeno_E3_CR2 PF02439.10 CBZ24105.1 - 3.3 7.3 8.6 9.4 5.8 0.1 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Amastin PF07344.6 CBZ24106.1 - 1.2e-49 167.8 7.1 1.5e-49 167.5 4.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein CD20 PF04103.10 CBZ24106.1 - 0.00016 21.6 0.0 0.017 15.0 0.0 2.2 1 1 1 2 2 2 2 CD20-like family Claudin_2 PF13903.1 CBZ24106.1 - 0.0011 18.6 4.6 0.0011 18.6 3.2 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF975 PF06161.6 CBZ24106.1 - 0.053 13.2 0.1 0.053 13.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF975) Amastin PF07344.6 CBZ24107.1 - 2.2e-52 176.7 13.0 2.6e-52 176.5 9.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ24107.1 - 1.8 8.2 21.2 5.1 6.7 13.5 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBZ24108.1 - 9.6e-53 177.9 7.6 1.1e-52 177.7 5.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ24108.1 - 1.2e-05 25.1 6.9 1.2e-05 25.1 4.8 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF4525 PF15027.1 CBZ24108.1 - 0.1 12.1 2.1 0.37 10.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DUF1440 PF07274.7 CBZ24108.1 - 0.19 11.7 1.9 0.18 11.7 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1440) Amastin PF07344.6 CBZ24109.1 - 2.7e-52 176.4 12.2 4.7e-52 175.7 8.4 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.6 CBZ24110.1 - 5.6e-49 165.7 9.1 6.6e-49 165.4 6.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein CD20 PF04103.10 CBZ24110.1 - 0.0026 17.7 0.5 0.12 12.3 0.0 2.6 1 1 1 2 2 2 1 CD20-like family Claudin_2 PF13903.1 CBZ24110.1 - 0.018 14.7 13.9 0.053 13.2 8.7 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction zf-DHHC PF01529.15 CBZ24110.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4525 PF15027.1 CBZ24110.1 - 2.5 7.6 4.6 9.3 5.7 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4525) Amastin PF07344.6 CBZ24112.1 - 8.5e-32 109.9 15.1 1e-31 109.6 10.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4337 PF14235.1 CBZ24112.1 - 0.064 13.1 0.2 0.17 11.7 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF4293 PF14126.1 CBZ24112.1 - 0.35 10.7 8.3 0.74 9.7 5.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF3307 PF11750.3 CBZ24112.1 - 0.54 10.0 6.6 1 9.0 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3307) Claudin_2 PF13903.1 CBZ24112.1 - 1.6 8.4 18.3 2.2 7.9 12.7 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBZ24113.1 - 1.4e-56 190.3 13.5 1.7e-56 190.1 9.3 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ24113.1 - 0.00065 19.4 16.0 0.00098 18.8 10.5 1.7 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBZ24114.1 - 9.3e-54 181.2 10.7 1.1e-53 180.9 7.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1517 PF07466.6 CBZ24115.1 - 4.2 6.2 4.7 1.1 8.1 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) CotJB PF12652.2 CBZ24116.1 - 0.036 14.1 7.7 0.22 11.6 0.7 4.0 3 1 1 4 4 4 0 CotJB protein DUF2408 PF10303.4 CBZ24116.1 - 0.04 14.0 0.8 0.11 12.5 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) HCMV_UL139 PF12507.3 CBZ24116.1 - 0.043 13.9 0.7 1.6 8.8 1.8 2.3 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Toxin_44 PF15523.1 CBZ24116.1 - 0.1 12.5 1.6 0.34 10.8 1.1 1.9 1 0 0 1 1 1 0 Putative toxin 44 BAR PF03114.13 CBZ24116.1 - 0.11 11.9 8.1 0.079 12.4 3.5 2.1 2 0 0 2 2 2 0 BAR domain SET PF00856.23 CBZ24117.1 - 2.7e-09 37.5 0.2 1.3e-07 32.0 0.6 2.9 2 2 0 2 2 2 1 SET domain DNA_pol_B_thumb PF14791.1 CBZ24118.1 - 7.4e-20 70.4 0.1 2.3e-19 68.8 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 CBZ24118.1 - 1.9e-17 63.3 0.0 4.1e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 CBZ24118.1 - 2.8e-15 55.6 0.1 1.1e-14 53.7 0.0 2.1 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 CBZ24118.1 - 1.1e-13 51.1 0.2 9e-12 45.0 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 CBZ24118.1 - 0.0032 17.5 0.0 0.22 11.6 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.1 CBZ24119.1 - 4.6e-26 91.0 0.0 1.1e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 CBZ24119.1 - 5.6e-19 67.5 0.4 1.3e-09 37.5 0.0 3.1 3 0 0 3 3 3 2 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 CBZ24119.1 - 1.1e-10 40.8 0.0 3.9e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 CBZ24119.1 - 0.0019 18.4 0.0 0.0057 16.9 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.1 CBZ24119.1 - 0.0052 16.9 0.0 0.19 11.9 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_8 PF14716.1 CBZ24119.1 - 0.0054 16.8 0.6 17 5.6 0.0 3.9 4 0 0 4 4 4 1 Helix-hairpin-helix domain HHH PF00633.18 CBZ24119.1 - 0.018 14.7 0.1 0.3 10.8 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Lactamase_B_2 PF12706.2 CBZ24120.1 - 1.6e-17 63.7 0.0 2e-15 56.8 0.0 3.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CBZ24120.1 - 2.3e-05 23.7 0.0 6.3e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 CBZ24120.1 - 0.00085 19.0 0.0 0.0042 16.7 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Pkinase PF00069.20 CBZ24122.1 - 5.9e-64 215.7 0.0 2.4e-63 213.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24122.1 - 9.4e-45 152.6 0.0 1.4e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ24122.1 - 1.6e-07 30.6 0.0 1e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Dpy-30 PF05186.8 CBZ24125.1 - 1.2e-06 27.8 0.1 2.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Dpy-30 motif DUF2453 PF10507.4 CBZ24126.1 - 1.2e-37 128.1 2.0 3.4e-37 126.6 1.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) DUF4611 PF15387.1 CBZ24127.1 - 1.4 9.1 7.8 6.6 6.9 4.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DnaJ PF00226.26 CBZ24128.1 - 1.1e-17 63.5 2.5 1.1e-07 31.4 0.3 2.8 2 1 0 2 2 2 2 DnaJ domain DUF3854 PF12965.2 CBZ24128.1 - 0.039 13.6 0.0 0.27 10.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3854) AAA_5 PF07728.9 CBZ24129.1 - 2e-81 270.5 0.0 8.5e-32 109.7 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 CBZ24129.1 - 6.4e-09 36.1 0.0 2e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_16 PF13191.1 CBZ24129.1 - 1.7e-06 28.1 12.5 0.00054 20.0 0.0 5.7 6 1 1 7 7 5 2 AAA ATPase domain AAA PF00004.24 CBZ24129.1 - 4.3e-06 26.9 0.0 0.02 15.0 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBZ24129.1 - 4.3e-05 23.4 0.0 0.078 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBZ24129.1 - 7.2e-05 22.2 0.0 0.31 10.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CBZ24129.1 - 9.9e-05 22.4 0.3 0.036 14.2 0.0 3.6 2 2 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CBZ24129.1 - 0.00033 20.2 0.0 0.14 11.7 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CBZ24129.1 - 0.0012 18.8 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.13 CBZ24129.1 - 0.0028 17.2 0.0 0.039 13.4 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 CBZ24129.1 - 0.0033 16.8 0.1 0.26 10.6 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein VWA PF00092.23 CBZ24129.1 - 0.0043 16.7 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Sigma54_activat PF00158.21 CBZ24129.1 - 0.0068 15.8 0.0 4.7 6.6 0.0 3.3 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_17 PF13207.1 CBZ24129.1 - 0.0085 16.9 0.0 0.92 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBZ24129.1 - 0.011 15.5 0.0 0.62 9.9 0.0 3.1 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CBZ24129.1 - 0.014 14.3 0.0 2 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 CBZ24129.1 - 0.018 14.1 1.9 0.68 9.0 0.1 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 CBZ24129.1 - 0.024 14.9 0.0 0.45 10.7 0.0 2.8 2 0 0 2 2 2 0 ABC transporter DUF615 PF04751.9 CBZ24129.1 - 0.025 14.2 1.3 0.07 12.7 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF615) UPF0079 PF02367.12 CBZ24129.1 - 0.037 13.6 0.1 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 CBZ24129.1 - 0.066 12.3 0.0 5.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Rad17 PF03215.10 CBZ24129.1 - 0.078 11.6 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 CBZ24129.1 - 0.089 12.4 0.0 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 CBZ24129.1 - 0.11 12.7 0.0 0.89 9.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.14 CBZ24129.1 - 0.12 11.5 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 CBZ24129.1 - 0.17 12.2 0.0 2.9 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Lon_2 PF13337.1 CBZ24129.1 - 0.22 9.8 0.0 0.36 9.1 0.0 1.2 1 0 0 1 1 1 0 Putative ATP-dependent Lon protease G-alpha PF00503.15 CBZ24129.1 - 1.7 7.2 0.0 3.4 6.2 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_23 PF13476.1 CBZ24129.1 - 1.9 8.7 0.0 4.7 7.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_C1 PF00112.18 CBZ24130.1 - 1.4e-71 240.8 0.9 1.9e-71 240.4 0.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBZ24130.1 - 5.1e-12 45.8 1.0 8.1e-12 45.2 0.7 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBZ24130.1 - 4.6e-06 25.4 0.2 0.00037 19.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.18 CBZ24131.1 - 7.6e-72 241.7 0.7 7.6e-72 241.7 0.5 1.9 2 0 0 2 2 2 1 Papain family cysteine protease DUF3586 PF12131.3 CBZ24131.1 - 1.4e-27 95.4 6.8 3.2e-27 94.4 4.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.7 CBZ24131.1 - 6.3e-12 45.5 1.0 1.1e-11 44.8 0.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBZ24131.1 - 7.7e-06 24.6 0.2 0.00049 18.7 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.18 CBZ24132.1 - 9.6e-72 241.4 0.8 1.2e-71 241.0 0.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBZ24132.1 - 5e-12 45.8 1.0 7.9e-12 45.2 0.7 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBZ24132.1 - 1e-06 27.5 0.2 3.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Hist_deacetyl PF00850.14 CBZ24133.1 - 1.5e-60 205.1 0.0 2.2e-60 204.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain zf-RING_2 PF13639.1 CBZ24134.1 - 2.2e-08 33.8 22.0 4.8e-08 32.7 3.7 4.0 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ24134.1 - 2.1e-05 24.4 5.9 2.1e-05 24.4 4.1 4.5 4 2 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ24134.1 - 0.00019 21.0 3.5 0.00019 21.0 2.5 4.7 4 3 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ24134.1 - 0.00027 20.5 6.3 0.00027 20.5 4.3 5.0 4 2 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) SnAC PF14619.1 CBZ24135.1 - 0.1 12.8 0.4 0.1 12.8 0.3 2.6 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex cwf21 PF08312.7 CBZ24135.1 - 2.8 7.8 9.3 0.095 12.5 0.8 2.8 3 0 0 3 3 3 0 cwf21 domain TPR_11 PF13414.1 CBZ24136.1 - 2.3e-66 219.3 27.0 5.8e-19 67.5 0.4 6.4 5 1 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 CBZ24136.1 - 3.7e-52 171.8 34.7 4e-08 32.5 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ24136.1 - 9.8e-43 140.6 34.8 1.1e-05 24.9 0.0 9.9 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ24136.1 - 1.1e-27 96.0 6.8 2.9e-05 24.6 0.1 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ24136.1 - 7.2e-21 73.9 23.1 2.9e-08 33.5 0.1 6.5 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ24136.1 - 3.9e-19 68.7 7.9 0.0019 18.4 0.0 6.7 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ24136.1 - 4.9e-18 63.9 7.0 0.058 14.0 0.0 9.4 5 3 5 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ24136.1 - 9.2e-16 56.3 26.4 0.029 14.1 0.0 8.8 8 1 1 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 CBZ24136.1 - 3.9e-15 55.7 21.0 2.8e-07 30.5 2.2 5.1 3 3 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBZ24136.1 - 6e-15 54.1 15.1 0.11 12.7 0.2 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ24136.1 - 1.8e-11 43.7 0.4 0.00028 20.6 0.0 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ24136.1 - 5.2e-11 41.4 11.5 0.1 12.4 0.0 8.8 8 0 0 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ24136.1 - 2.4e-07 30.5 3.6 1.1 9.1 0.0 6.0 7 0 0 7 7 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 CBZ24136.1 - 0.00039 20.4 0.3 1.6 8.8 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 CBZ24136.1 - 0.0013 18.5 24.1 2.1 8.2 0.0 7.2 6 1 0 7 7 7 2 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 CBZ24136.1 - 0.0023 17.8 13.8 34 4.5 0.0 7.8 9 0 0 9 9 7 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBZ24136.1 - 0.012 14.8 11.6 0.53 9.5 0.0 5.6 7 0 0 7 7 7 0 SHNi-TPR DUF3856 PF12968.2 CBZ24136.1 - 0.074 12.8 7.6 5.7 6.7 0.1 4.9 3 3 2 5 5 5 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 CBZ24136.1 - 0.1 13.1 25.4 7.8 7.2 0.1 8.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_3 PF07720.7 CBZ24136.1 - 1.7 8.5 27.6 3.2 7.6 0.2 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.4 CBZ24136.1 - 2.5 7.4 8.1 0.82 9.0 0.6 3.3 1 1 1 3 3 3 0 26S proteasome subunit RPN7 DUF1126 PF06565.7 CBZ24137.1 - 4.1e-16 58.1 0.0 5e-11 41.8 0.0 3.7 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_1 PF00036.27 CBZ24137.1 - 0.0034 16.5 0.0 0.011 14.9 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CBZ24137.1 - 0.024 14.7 0.0 5 7.3 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 CBZ24137.1 - 0.033 14.0 0.0 0.57 10.2 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.1 CBZ24137.1 - 0.041 13.5 0.0 0.16 11.6 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.1 CBZ24137.1 - 0.055 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 EF hand Pribosyltran_N PF13793.1 CBZ24138.1 - 6.2e-35 119.4 0.0 1.4e-34 118.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CBZ24138.1 - 5.8e-24 84.8 0.3 2.1e-23 83.0 0.1 1.8 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBZ24138.1 - 1.7e-13 50.3 1.7 5e-13 48.8 1.2 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBZ24138.1 - 0.0049 16.0 0.1 0.0089 15.2 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Sec3_C PF09763.4 CBZ24140.1 - 4.6e-76 256.4 1.5 1.2e-37 129.4 0.2 2.1 2 0 0 2 2 2 2 Exocyst complex component Sec3 DUF2450 PF10475.4 CBZ24140.1 - 0.0098 14.8 4.8 0.027 13.4 3.4 1.7 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF812 PF05667.6 CBZ24140.1 - 0.018 13.6 5.8 0.016 13.7 2.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) DUF2203 PF09969.4 CBZ24140.1 - 0.13 12.4 0.9 0.41 10.8 0.6 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) IncA PF04156.9 CBZ24140.1 - 0.39 10.2 8.3 0.93 9.0 5.8 1.6 1 0 0 1 1 1 0 IncA protein TPMT PF05724.6 CBZ24141.1 - 4.6e-16 58.9 0.0 9.6e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 CBZ24141.1 - 0.0026 17.4 0.0 0.0043 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ24141.1 - 0.053 14.1 0.0 0.13 12.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain FAST_1 PF06743.10 CBZ24142.1 - 0.031 13.9 0.3 1.3 8.8 0.0 3.3 3 1 1 4 4 4 0 FAST kinase-like protein, subdomain 1 PhageMin_Tail PF10145.4 CBZ24142.1 - 1.4 8.5 6.9 4.1 6.9 0.1 3.6 3 1 0 4 4 4 0 Phage-related minor tail protein Slu7 PF11708.3 CBZ24143.1 - 0.0012 18.6 4.4 0.007 16.1 3.2 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_3 PF13917.1 CBZ24143.1 - 0.0056 16.3 0.6 0.017 14.8 0.4 1.8 1 0 0 1 1 1 1 Zinc knuckle tRNA-synt_1c PF00749.16 CBZ24143.1 - 0.061 11.9 0.8 0.11 11.0 0.1 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain zf-CCHC_5 PF14787.1 CBZ24143.1 - 0.084 12.3 1.4 0.16 11.4 1.0 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Coatomer_WDAD PF04053.9 CBZ24144.1 - 1.1e-10 40.8 3.1 0.00023 20.1 0.1 4.3 5 0 0 5 5 5 2 Coatomer WD associated region WD40 PF00400.27 CBZ24144.1 - 2.7e-07 30.2 10.2 0.65 9.9 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat TPR_7 PF13176.1 CBZ24144.1 - 2.3e-05 23.8 6.1 0.042 13.6 0.3 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat Clathrin PF00637.15 CBZ24144.1 - 0.00031 20.3 1.8 1.2 8.6 0.1 4.0 2 1 1 3 3 3 2 Region in Clathrin and VPS eIF2A PF08662.6 CBZ24144.1 - 0.0062 16.2 0.0 0.2 11.3 0.0 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A zf-RanBP PF00641.13 CBZ24144.1 - 0.0087 15.1 10.7 0.01 14.8 1.9 2.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Vps39_1 PF10366.4 CBZ24144.1 - 0.03 14.3 0.2 0.11 12.5 0.2 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 TPR_12 PF13424.1 CBZ24144.1 - 0.085 12.8 16.2 0.41 10.6 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ24144.1 - 0.09 13.4 14.1 0.087 13.5 0.5 5.2 4 1 0 4 4 4 0 Tetratricopeptide repeat DZR PF12773.2 CBZ24144.1 - 1.2 9.0 13.0 8.7 6.2 9.0 2.5 1 1 0 1 1 1 0 Double zinc ribbon TPR_2 PF07719.12 CBZ24144.1 - 1.3 9.1 20.6 0.81 9.7 0.7 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ24144.1 - 2.3 7.9 11.4 0.96 9.1 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ24144.1 - 3.5 7.3 20.0 0.3 10.7 0.3 5.0 5 0 0 5 5 5 0 TPR repeat zf-C3HC4_2 PF13923.1 CBZ24147.1 - 1.8e-10 40.6 8.9 4.6e-10 39.3 6.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ24147.1 - 3e-09 36.4 8.3 3e-09 36.4 5.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ24147.1 - 1.8e-08 34.1 8.1 5.1e-08 32.6 5.6 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBZ24147.1 - 2.1e-08 33.8 8.8 5.5e-08 32.5 6.1 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBZ24147.1 - 1.2e-07 31.2 7.6 1.2e-07 31.2 5.3 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ24147.1 - 8.2e-07 28.5 7.5 8.2e-07 28.5 5.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBZ24147.1 - 2.6e-05 23.8 8.0 9.2e-05 22.0 5.5 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 CBZ24147.1 - 0.0024 17.9 4.9 0.0099 15.9 3.4 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBZ24147.1 - 0.037 13.8 2.7 0.086 12.6 1.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 CBZ24147.1 - 0.04 13.8 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 U-box domain zf-Nse PF11789.3 CBZ24147.1 - 0.45 10.0 6.7 0.93 9.0 4.7 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.16 CBZ24147.1 - 1.1 9.1 4.6 3.1 7.7 1.7 2.4 2 0 0 2 2 2 0 FYVE zinc finger KduI PF04962.7 CBZ24149.1 - 0.0046 16.0 0.1 0.0051 15.9 0.1 1.1 1 0 0 1 1 1 1 KduI/IolB family GBA2_N PF12215.3 CBZ24149.1 - 0.014 14.5 0.2 0.016 14.4 0.2 1.0 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal Amidinotransf PF02274.12 CBZ24151.1 - 3.1e-20 72.4 0.0 4.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Amidinotransferase Pkinase PF00069.20 CBZ24152.1 - 1.4e-49 168.6 0.0 2e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24152.1 - 1.4e-33 116.0 0.0 2.4e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ24152.1 - 7.6e-06 25.0 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBZ24152.1 - 0.0031 16.9 0.0 0.0067 15.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBZ24152.1 - 0.058 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tubulin PF00091.20 CBZ24153.1 - 7e-70 235.2 0.0 1.1e-69 234.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ24153.1 - 1.7e-48 163.7 0.0 2.6e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBZ24153.1 - 5e-05 23.3 0.0 9.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBZ24153.1 - 0.0071 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 CBZ24154.1 - 2.8e-70 236.5 0.0 4.5e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ24154.1 - 6.5e-48 161.9 0.1 9.7e-48 161.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBZ24154.1 - 5.8e-05 23.1 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBZ24154.1 - 0.0078 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF3138 PF11336.3 CBZ24155.1 - 0.0098 14.1 0.5 0.012 13.8 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) YliH PF10799.3 CBZ24155.1 - 0.024 14.3 0.2 0.036 13.7 0.1 1.3 1 1 0 1 1 1 0 Biofilm formation protein (YliH/bssR) Birna_VP5 PF03042.9 CBZ24155.1 - 0.088 12.3 0.7 0.4 10.1 0.0 2.0 1 1 1 2 2 2 0 Birnavirus VP5 protein PP2C_C PF07830.8 CBZ24155.1 - 0.11 12.6 0.4 0.25 11.4 0.3 1.5 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF2381 PF09544.5 CBZ24155.1 - 0.24 10.4 3.4 0.26 10.3 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2381) bZIP_Maf PF03131.12 CBZ24155.1 - 0.5 10.7 5.2 12 6.2 0.7 2.9 2 1 1 3 3 3 0 bZIP Maf transcription factor SlyX PF04102.7 CBZ24155.1 - 0.81 10.1 4.7 11 6.5 0.3 2.3 2 0 0 2 2 2 0 SlyX DUF1192 PF06698.6 CBZ24155.1 - 0.95 9.3 8.6 7.8 6.3 1.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF4200 PF13863.1 CBZ24155.1 - 1.2 9.0 7.9 0.54 10.2 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Med9 PF07544.8 CBZ24155.1 - 2 8.1 4.9 2.7 7.7 0.1 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF2415 PF10313.4 CBZ24156.1 - 0.1 12.2 0.4 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 CBZ24156.1 - 0.16 11.9 8.3 2.4 8.1 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat PEX11 PF05648.9 CBZ24159.1 - 9.9e-09 34.7 5.9 1.7e-06 27.4 4.1 2.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PIG-L PF02585.12 CBZ24160.1 - 9.8e-25 87.5 0.0 1.4e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HhH-GPD PF00730.20 CBZ24161.1 - 1.6e-20 73.4 0.0 2.5e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CBZ24161.1 - 2.3e-05 23.8 0.0 5.9e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 CBZ24161.1 - 0.00011 22.2 4.1 0.00021 21.3 2.8 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III CRS1_YhbY PF01985.16 CBZ24161.1 - 0.059 13.3 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 CRS1 / YhbY (CRM) domain RRM_1 PF00076.17 CBZ24162.1 - 2.2e-21 75.2 0.0 2.7e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ24162.1 - 9.5e-17 60.7 0.0 1.5e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ24162.1 - 5.3e-09 35.8 0.0 8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CBZ24162.1 - 0.063 13.2 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 RNA binding domain Rogdi_lz PF10259.4 CBZ24162.1 - 0.07 12.2 0.0 0.081 12.0 0.0 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein HA2 PF04408.18 CBZ24163.1 - 1.4e-18 66.7 0.7 7e-18 64.5 0.0 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBZ24163.1 - 3.5e-12 46.1 0.0 1.6e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBZ24163.1 - 1.5e-11 44.0 0.1 3.7e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ24163.1 - 1.3e-10 41.0 0.3 1.2e-09 37.9 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 CBZ24163.1 - 2.6e-05 23.2 0.0 5.9e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein RWD PF05773.17 CBZ24163.1 - 3.2e-05 23.7 0.0 0.00011 22.0 0.0 2.0 1 0 0 1 1 1 1 RWD domain zf-CCHC PF00098.18 CBZ24163.1 - 0.00018 21.2 1.8 0.00018 21.2 1.2 2.7 2 0 0 2 2 2 1 Zinc knuckle AAA_22 PF13401.1 CBZ24163.1 - 0.00026 21.1 0.3 0.0015 18.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBZ24163.1 - 0.056 12.9 0.2 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 CBZ24163.1 - 0.074 13.1 0.0 0.65 10.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 CBZ24163.1 - 0.082 12.0 0.1 0.2 10.7 0.0 1.6 1 0 0 1 1 1 0 KaiC ResIII PF04851.10 CBZ24163.1 - 0.1 12.4 0.1 3.7 7.3 0.1 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 CBZ24163.1 - 0.13 12.5 0.0 0.37 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 CBZ24163.1 - 0.28 11.5 1.8 0.5 10.6 0.1 2.3 3 0 0 3 3 3 0 AAA domain RRM_1 PF00076.17 CBZ24164.1 - 7.6e-19 67.1 0.0 1.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ24164.1 - 2.2e-14 53.1 0.0 3.7e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ24164.1 - 1.6e-08 34.2 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lactonase PF10282.4 CBZ24164.1 - 0.0066 15.5 0.1 0.0099 14.9 0.1 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Limkain-b1 PF11608.3 CBZ24164.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 Limkain b1 RRM_1 PF00076.17 CBZ24165.1 - 2.2e-16 59.2 0.0 3.4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ24165.1 - 2.6e-09 36.9 0.0 4.2e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ24165.1 - 1.9e-06 27.6 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_7 PF13499.1 CBZ24166.1 - 1.1e-08 35.0 5.5 1.2e-08 34.9 2.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ24166.1 - 6.2e-06 25.1 3.9 0.0056 15.8 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBZ24166.1 - 1.9e-05 24.1 0.5 0.0014 18.2 0.3 2.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ24166.1 - 0.0045 16.7 2.5 1.4 9.0 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBZ24166.1 - 0.037 13.3 0.0 0.12 11.7 0.0 2.0 1 0 0 1 1 1 0 EF hand DUF3584 PF12128.3 CBZ24166.1 - 5 4.3 63.3 0.32 8.2 23.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 CBZ24166.1 - 6.2 5.9 9.1 12 4.9 1.2 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Tropomyosin PF00261.15 CBZ24166.1 - 7.1 5.6 66.3 1.3 8.0 10.2 3.5 1 1 1 2 2 2 0 Tropomyosin Fib_alpha PF08702.5 CBZ24166.1 - 7.3 6.7 23.1 1.9 8.5 0.5 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Kinesin PF00225.18 CBZ24169.1 - 5.3e-78 262.0 0.1 6.5e-46 156.5 0.0 3.0 2 1 0 2 2 2 2 Kinesin motor domain AAA_22 PF13401.1 CBZ24169.1 - 0.048 13.8 2.9 0.07 13.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 CBZ24169.1 - 0.095 12.5 0.0 0.095 12.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 FHA PF00498.21 CBZ24170.1 - 4.9e-15 55.4 0.2 9.9e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CBZ24170.1 - 1.2e-07 31.3 13.6 1.2e-07 31.3 9.4 3.2 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ24170.1 - 2.5e-07 30.2 12.3 2.5e-07 30.2 8.5 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ24170.1 - 3.6e-06 26.8 14.4 3.6e-06 26.8 10.0 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ24170.1 - 6.3e-06 25.8 12.0 6.3e-06 25.8 8.3 3.3 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ24170.1 - 9.9e-06 25.3 13.1 9.9e-06 25.3 9.1 3.3 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CBZ24170.1 - 0.00093 18.9 6.8 0.00093 18.9 4.7 3.1 2 1 1 3 3 3 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 CBZ24170.1 - 0.003 17.0 6.1 0.0083 15.6 4.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 CBZ24170.1 - 0.0057 16.7 7.5 0.0057 16.7 5.2 2.8 3 0 0 3 3 3 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBZ24170.1 - 0.0098 15.5 11.2 0.031 13.9 7.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Atg8 PF02991.11 CBZ24171.1 - 4.8e-06 26.5 0.0 8.1e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pox_Ag35 PF03286.9 CBZ24171.1 - 0.071 12.6 0.3 0.092 12.2 0.2 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Atg8 PF02991.11 CBZ24172.1 - 5.5e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like NRDE PF05742.7 CBZ24174.1 - 1.1e-15 57.7 0.0 3.5e-12 46.2 0.0 3.3 3 0 0 3 3 3 3 NRDE protein DUF4586 PF15239.1 CBZ24175.1 - 5.7e-36 124.6 2.7 7.3e-36 124.2 1.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) VTC PF09359.5 CBZ24176.1 - 1.9e-76 256.7 0.2 2.9e-76 256.1 0.1 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.10 CBZ24176.1 - 0.00014 21.9 0.7 0.00014 21.9 0.5 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MASE1 PF05231.9 CBZ24176.1 - 0.0066 15.5 0.6 0.012 14.6 0.4 1.4 1 0 0 1 1 1 1 MASE1 Ferric_reduct PF01794.14 CBZ24176.1 - 0.027 14.5 1.3 0.074 13.1 0.9 1.7 1 0 0 1 1 1 0 Ferric reductase like transmembrane component RinB PF06116.7 CBZ24176.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional activator RinB AAA_2 PF07724.9 CBZ24177.1 - 5.6e-42 143.5 0.2 1.3e-33 116.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBZ24177.1 - 9.9e-13 48.4 0.5 6.8e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CBZ24177.1 - 1.7e-06 27.8 0.1 8.6e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CBZ24177.1 - 3.4e-06 26.8 0.1 7.4e-05 22.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ24177.1 - 2.2e-05 24.5 0.0 0.0021 18.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBZ24177.1 - 4.5e-05 24.2 0.0 0.0011 19.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ24177.1 - 0.00026 21.0 2.0 0.006 16.5 1.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CBZ24177.1 - 0.00091 19.5 0.0 0.038 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain MCM PF00493.18 CBZ24177.1 - 0.0015 17.3 0.1 0.069 11.9 0.0 2.4 2 0 0 2 2 2 1 MCM2/3/5 family ATP-synt_ab PF00006.20 CBZ24177.1 - 0.0018 17.8 0.1 0.0033 16.9 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 CBZ24177.1 - 0.014 14.5 1.1 0.083 11.9 0.3 2.3 1 1 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 CBZ24177.1 - 0.015 14.7 0.0 0.18 11.2 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.7 CBZ24177.1 - 0.019 14.0 0.0 0.33 9.9 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CBZ24177.1 - 0.047 13.5 0.1 0.24 11.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CBZ24177.1 - 0.047 12.8 2.9 0.053 12.6 0.0 2.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CBZ24177.1 - 0.051 13.4 0.7 9.8 6.0 0.0 2.8 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.22 CBZ24177.1 - 0.072 13.3 0.0 0.49 10.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 CBZ24177.1 - 0.074 12.7 0.0 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 CBZ24177.1 - 0.077 12.8 0.1 0.96 9.2 0.0 2.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit G-alpha PF00503.15 CBZ24177.1 - 0.092 11.4 0.1 0.19 10.3 0.0 1.6 1 1 0 1 1 1 0 G-protein alpha subunit UCH PF00443.24 CBZ24178.1 - 2e-38 132.0 0.0 1.2e-37 129.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ24178.1 - 0.00024 20.6 0.0 0.02 14.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Lipid_DES PF08557.5 CBZ24178.1 - 0.051 12.8 0.1 0.15 11.3 0.0 1.8 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) MCM PF00493.18 CBZ24179.1 - 6.6e-120 399.8 0.0 2.6e-119 397.9 0.0 1.9 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBZ24179.1 - 7.6e-12 45.7 0.0 4.1e-11 43.4 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 CBZ24179.1 - 4.8e-09 36.0 0.0 9.7e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBZ24179.1 - 5.8e-08 32.1 0.0 1.2e-05 24.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CBZ24179.1 - 0.001 18.5 0.0 0.042 13.3 0.0 2.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 CBZ24179.1 - 0.0028 17.2 0.0 0.007 15.9 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) G10 PF01125.12 CBZ24180.1 - 1.8e-51 173.5 1.4 2.9e-47 159.8 0.8 2.1 2 0 0 2 2 2 2 G10 protein MFS_1 PF07690.11 CBZ24181.1 - 1.3e-23 83.2 35.8 4.1e-18 65.2 10.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.18 CBZ24183.1 - 8.1e-32 110.2 0.0 7.4e-11 41.3 0.0 3.9 3 1 0 3 3 3 3 Kinesin motor domain WD-3 PF09765.4 CBZ24184.1 - 0.037 13.3 0.1 0.05 12.8 0.1 1.1 1 0 0 1 1 1 0 WD-repeat region Pkinase PF00069.20 CBZ24185.1 - 1e-48 165.7 0.0 2.1e-48 164.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24185.1 - 3e-20 72.3 0.2 2.8e-19 69.1 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ24185.1 - 1.4e-06 27.4 0.0 3.6e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBZ24185.1 - 0.00022 21.0 0.0 0.00022 21.0 0.0 2.3 2 2 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ24185.1 - 0.077 12.3 0.1 0.54 9.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family DUF1500 PF07389.7 CBZ24188.1 - 0.032 14.2 0.2 0.077 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1500) Tmemb_9 PF05434.6 CBZ24188.1 - 0.18 11.5 1.7 15 5.2 0.2 2.4 2 0 0 2 2 2 0 TMEM9 EphA2_TM PF14575.1 CBZ24188.1 - 0.24 11.8 1.7 12 6.4 0.0 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-RING_2 PF13639.1 CBZ24190.1 - 1.5e-09 37.4 10.9 3.4e-09 36.3 5.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBZ24190.1 - 9.2e-08 32.0 2.6 2.3e-07 30.8 0.7 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBZ24190.1 - 8.8e-05 22.4 8.2 8.8e-05 22.4 5.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ24190.1 - 0.00015 21.3 6.4 0.00015 21.3 4.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ24190.1 - 0.0003 20.3 2.8 0.0003 20.3 2.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBZ24190.1 - 0.00054 19.7 1.8 0.0015 18.3 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CBZ24190.1 - 0.0019 17.8 5.5 0.0019 17.8 3.8 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ24190.1 - 3.9 7.4 9.6 0.87 9.5 3.7 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FAD_binding_7 PF03441.9 CBZ24191.1 - 4.6e-44 150.6 0.3 7.1e-44 150.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CBZ24191.1 - 1.3e-19 70.5 0.3 7.3e-19 68.1 0.1 2.3 2 0 0 2 2 2 1 DNA photolyase Ank_2 PF12796.2 CBZ24192.1 - 3.5e-08 33.6 0.0 6.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ24192.1 - 1.3e-07 31.9 0.0 4.7e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBZ24192.1 - 2.3e-05 23.9 0.0 0.00075 19.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CBZ24192.1 - 3.9e-05 23.4 0.2 0.00072 19.5 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 CBZ24192.1 - 0.0037 17.4 0.0 0.014 15.6 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Cmc1 PF08583.5 CBZ24193.1 - 0.03 14.0 2.3 0.098 12.4 1.2 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CBZ24193.1 - 0.033 14.1 1.6 3.6 7.6 0.1 2.2 2 0 0 2 2 2 0 CHCH domain UPF0203 PF05254.7 CBZ24193.1 - 0.13 12.1 1.8 8.2 6.3 0.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) NDUF_B7 PF05676.8 CBZ24193.1 - 0.8 9.1 6.0 3.5 7.1 0.8 2.4 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Het-C PF07217.6 CBZ24195.1 - 0.029 12.6 0.1 0.041 12.0 0.1 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DUF755 PF05501.6 CBZ24195.1 - 2.2 8.3 8.2 3.4 7.7 3.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF755) Pox_G7 PF05503.7 CBZ24196.1 - 0.58 8.7 0.0 1.1 7.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus G7-like Pkinase PF00069.20 CBZ24197.1 - 3.1e-50 170.7 0.0 3.9e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24197.1 - 1.3e-16 60.4 0.0 1.9e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ24197.1 - 0.011 15.4 0.3 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CBZ24197.1 - 0.056 12.4 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSPn PF14671.1 CBZ24198.1 - 3.4e-21 75.7 0.0 4.6e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CBZ24198.1 - 3e-08 33.3 0.1 5.6e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ24198.1 - 0.00024 20.4 0.1 0.00041 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CBZ24198.1 - 0.31 11.0 0.2 0.64 10.0 0.2 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate zf-C3HC4_3 PF13920.1 CBZ24199.1 - 1.4e-10 40.6 15.6 2.2e-10 40.0 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Plus-3 PF03126.13 CBZ24199.1 - 1e-07 31.9 0.0 2.5e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_2 PF13923.1 CBZ24199.1 - 0.51 10.4 18.2 0.93 9.5 12.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ24199.1 - 2.8 7.8 16.5 6.1 6.7 11.5 1.6 1 0 0 1 1 1 0 Ring finger domain TPR_11 PF13414.1 CBZ24200.1 - 5.9e-24 83.4 14.5 1.9e-07 30.6 0.0 6.8 4 1 1 7 7 7 6 TPR repeat TPR_14 PF13428.1 CBZ24200.1 - 1.6e-15 56.2 9.3 0.023 15.2 0.0 6.8 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ24200.1 - 1.8e-15 55.7 16.6 0.002 17.6 0.0 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ24200.1 - 4.6e-13 48.0 17.5 0.058 13.3 0.0 8.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ24200.1 - 6.9e-11 41.1 0.2 0.67 9.8 0.0 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ24200.1 - 1.5e-09 38.2 19.3 0.011 16.3 0.3 6.3 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ24200.1 - 3.6e-09 36.4 18.0 0.005 16.7 0.0 6.3 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ24200.1 - 9.1e-09 35.0 10.7 9.4e-05 22.1 0.3 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ24200.1 - 6.9e-05 23.1 14.2 0.41 11.0 1.0 5.6 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ24200.1 - 0.00011 22.0 8.7 13 6.2 0.0 7.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ24200.1 - 0.00089 19.5 10.8 8.5 7.0 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ24200.1 - 0.032 14.0 11.9 0.33 10.8 0.0 4.9 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 CBZ24200.1 - 0.48 10.3 6.6 74 3.5 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ24200.1 - 1.3 9.0 11.2 30 4.7 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat P-mevalo_kinase PF04275.9 CBZ24201.1 - 0.039 13.6 0.2 9 6.0 0.1 2.6 2 0 0 2 2 2 0 Phosphomevalonate kinase DUF1981 PF09324.5 CBZ24202.1 - 0.11 12.0 0.1 2.4 7.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Metallophos PF00149.23 CBZ24203.1 - 5.1e-23 81.5 1.3 7.3e-23 81.0 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Herpes_BLRF2 PF05812.7 CBZ24203.1 - 0.078 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF1192 PF06698.6 CBZ24203.1 - 0.16 11.8 0.5 0.32 10.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) IRK PF01007.15 CBZ24204.1 - 0.00029 19.7 2.3 0.061 12.1 0.0 3.0 3 0 0 3 3 3 3 Inward rectifier potassium channel Acyltransferase PF01553.16 CBZ24205.1 - 0.0067 15.8 0.1 0.065 12.6 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase LRR_6 PF13516.1 CBZ24209.1 - 0.0015 18.3 3.1 1.9 8.7 0.0 4.8 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.28 CBZ24209.1 - 0.0018 18.0 2.1 1.5 9.0 0.0 5.1 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_4 PF12799.2 CBZ24209.1 - 0.0066 16.0 4.0 4 7.1 0.0 5.1 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24209.1 - 0.038 13.7 11.2 3 7.6 0.0 5.2 3 2 2 5 5 5 0 Leucine rich repeat LRR_7 PF13504.1 CBZ24209.1 - 0.45 10.9 13.8 11 6.7 0.0 6.9 6 0 0 6 6 6 0 Leucine rich repeat Cep57_CLD_2 PF14197.1 CBZ24209.1 - 6.6 6.7 11.3 0.9 9.5 0.1 3.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DSPc PF00782.15 CBZ24211.1 - 1.3e-07 31.2 0.0 6.2e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ24211.1 - 0.065 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase His_Phos_1 PF00300.17 CBZ24212.1 - 6.2e-13 49.1 0.0 1.3e-12 48.0 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CBZ24212.1 - 0.033 13.5 0.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) LRR_8 PF13855.1 CBZ24214.1 - 3.8e-06 26.5 0.1 0.022 14.4 0.0 2.7 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CBZ24214.1 - 0.033 13.8 0.4 4 7.1 0.2 3.1 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) UvrD-helicase PF00580.16 CBZ24215.1 - 5.2e-39 134.3 0.0 3.6e-20 72.5 0.0 2.4 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.1 CBZ24215.1 - 4.2e-27 95.5 0.0 9.9e-13 48.2 0.0 2.4 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CBZ24215.1 - 1.7e-13 50.0 0.8 6.6e-13 48.2 0.5 2.1 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 CBZ24215.1 - 1.5e-09 37.9 0.0 6.1e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 CBZ24215.1 - 5.9e-08 32.5 0.1 2.2e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CBZ24215.1 - 0.0018 17.8 0.0 2.5 7.5 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Peptidase_S51 PF03575.12 CBZ24216.1 - 1.2e-18 67.2 0.0 1.3e-16 60.7 0.0 2.1 1 1 0 1 1 1 1 Peptidase family S51 PRKCSH-like PF12999.2 CBZ24217.1 - 1.5e-08 34.4 0.2 4.8e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like Ldl_recept_a PF00057.13 CBZ24217.1 - 0.41 10.5 3.1 11 6.0 0.7 2.5 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF2360 PF10152.4 CBZ24217.1 - 0.57 10.4 3.0 1.3 9.2 1.1 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PH PF00169.24 CBZ24219.1 - 4.5e-10 39.6 0.0 7.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 CBZ24219.1 - 0.18 11.8 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain zf-DHHC PF01529.15 CBZ24220.1 - 4.9e-29 100.9 4.8 4.9e-29 100.9 3.3 2.2 2 2 0 2 2 2 1 DHHC palmitoyltransferase AAA_33 PF13671.1 CBZ24221.1 - 1.1e-07 31.7 0.3 3e-06 27.1 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ24221.1 - 2.1e-07 31.7 0.0 2.3e-06 28.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ24221.1 - 5.5e-06 25.6 0.0 1.3e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 CBZ24221.1 - 9.7e-05 22.4 0.3 0.00079 19.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CBZ24221.1 - 0.00024 21.3 0.0 0.0012 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CBZ24221.1 - 0.0016 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_28 PF13521.1 CBZ24221.1 - 0.015 15.2 0.0 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CBZ24221.1 - 0.033 14.3 0.0 0.32 11.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.22 CBZ24221.1 - 0.047 13.9 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Helicase_RecD PF05127.9 CBZ24221.1 - 0.069 12.7 0.0 0.69 9.5 0.0 2.2 2 0 0 2 2 2 0 Helicase AAA_29 PF13555.1 CBZ24221.1 - 0.07 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBZ24221.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 CBZ24221.1 - 0.08 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PRK PF00485.13 CBZ24221.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 CBZ24221.1 - 0.1 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CBZ24221.1 - 0.15 11.7 0.0 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 CBZ24221.1 - 0.23 11.1 0.0 0.46 10.1 0.0 1.5 1 0 0 1 1 1 0 NTPase TYW3 PF02676.9 CBZ24222.1 - 5.4e-42 143.2 0.0 1.7e-20 73.0 0.0 2.0 2 0 0 2 2 2 2 Methyltransferase TYW3 Prefoldin_2 PF01920.15 CBZ24223.1 - 3.9e-18 65.1 2.7 5e-18 64.8 1.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.5 CBZ24223.1 - 0.0034 17.0 2.5 0.0071 16.0 0.5 2.0 2 0 0 2 2 2 1 DASH complex subunit Dad3 DUF939_C PF11728.3 CBZ24223.1 - 0.03 14.1 1.5 0.084 12.6 0.1 1.9 2 0 0 2 2 2 0 DUF939 C-terminal domain Spc24 PF08286.6 CBZ24223.1 - 0.1 12.3 4.5 2.8 7.6 0.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FliD_C PF07195.7 CBZ24223.1 - 0.1 11.8 0.8 0.75 9.0 0.0 2.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF2011 PF09428.5 CBZ24223.1 - 0.11 12.3 1.6 0.91 9.4 1.1 2.0 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) TBPIP PF07106.8 CBZ24223.1 - 0.2 11.1 4.9 0.51 9.8 0.3 2.3 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Microtub_bind PF13931.1 CBZ24223.1 - 0.28 11.3 4.7 0.47 10.6 0.8 2.0 1 1 1 2 2 2 0 Kinesin-associated microtubule-binding NTR2 PF15458.1 CBZ24223.1 - 0.43 9.7 4.5 6.8 5.8 0.1 2.1 2 0 0 2 2 2 0 Nineteen complex-related protein 2 DUF3835 PF12927.2 CBZ24223.1 - 0.45 11.5 4.1 0.37 11.7 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) SlyX PF04102.7 CBZ24223.1 - 0.99 9.8 5.2 1.8 9.0 0.1 2.4 2 1 0 2 2 2 0 SlyX APG6 PF04111.7 CBZ24223.1 - 1.8 7.4 5.2 1.2 8.1 0.7 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 zf-CCCH PF00642.19 CBZ24228.1 - 4e-16 58.2 30.8 0.00025 20.6 0.2 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 CBZ24228.1 - 6.7e-07 28.9 6.1 0.00014 21.6 0.4 3.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 CBZ24228.1 - 2.9e-05 23.4 11.0 0.00032 20.1 0.6 3.2 2 0 0 2 2 2 2 Zinc knuckle zf-CCCH_2 PF14608.1 CBZ24228.1 - 0.033 14.1 0.1 0.033 14.1 0.1 6.2 6 1 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type zf-UBR PF02207.15 CBZ24230.1 - 1.1e-16 60.2 12.9 1.1e-16 60.2 9.0 2.8 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Rtf2 PF04641.7 CBZ24230.1 - 5.6 6.0 10.2 0.93 8.6 0.5 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger ACBP PF00887.14 CBZ24231.1 - 5.9e-24 83.5 0.3 1.1e-23 82.6 0.2 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4486 PF14858.1 CBZ24232.1 - 0.0011 17.3 0.0 0.0019 16.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) Peptidase_S9_N PF02897.10 CBZ24233.1 - 4.8e-122 407.4 0.4 6.2e-122 407.1 0.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CBZ24233.1 - 4.4e-66 222.1 0.0 7.4e-66 221.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 CBZ24233.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF4464 PF14713.1 CBZ24234.1 - 1.6e-82 276.4 0.3 1.8e-82 276.2 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) MT PF12777.2 CBZ24236.1 - 4.1e-07 29.0 0.0 4.1e-07 29.0 0.0 3.5 4 0 0 4 4 4 2 Microtubule-binding stalk of dynein motor FlaC_arch PF05377.6 CBZ24236.1 - 6.1 6.8 8.8 33 4.4 0.1 4.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.12 CBZ24237.1 - 3.5e-09 36.3 0.2 2.5e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit AAA PF00004.24 CBZ24238.1 - 8.5e-05 22.7 0.0 0.00025 21.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CBZ24238.1 - 0.0096 15.0 0.0 0.031 13.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 CBZ24238.1 - 0.015 15.4 0.0 0.059 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CBZ24238.1 - 0.035 14.1 1.8 0.54 10.2 0.1 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 CBZ24238.1 - 0.13 13.0 0.0 0.31 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 CBZ24239.1 - 5.8e-25 87.7 0.1 1e-24 86.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ24239.1 - 2.3e-18 65.8 0.0 1.1e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ24239.1 - 8.6e-05 22.4 0.0 0.00015 21.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UPF0160 PF03690.8 CBZ24240.1 - 1.7e-120 402.2 0.0 1.9e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ras PF00071.17 CBZ24241.1 - 3.2e-35 120.9 0.0 3.6e-11 42.7 0.0 3.0 3 0 0 3 3 3 3 Ras family Miro PF08477.8 CBZ24241.1 - 7.7e-09 36.0 0.0 3.7e-08 33.8 0.0 2.1 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBZ24241.1 - 0.00028 20.1 0.0 1.5 8.0 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family AAA_22 PF13401.1 CBZ24241.1 - 0.048 13.7 0.0 0.088 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain GPP34 PF05719.6 CBZ24242.1 - 0.036 14.1 0.1 0.039 14.0 0.1 1.1 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Hydrolase PF00702.21 CBZ24245.1 - 1.6e-12 48.2 0.1 0.00016 22.1 0.0 3.8 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ24245.1 - 7.4e-09 36.0 0.0 1e-05 25.8 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBZ24245.1 - 4.3e-08 32.4 0.0 1.1e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.7 CBZ24245.1 - 0.017 14.7 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase ubiquitin PF00240.18 CBZ24246.1 - 5.7e-34 115.3 0.3 7.8e-34 114.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CBZ24246.1 - 3.1e-32 109.9 13.9 5e-32 109.2 9.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CBZ24246.1 - 2.1e-20 72.1 0.2 3e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ24246.1 - 8.2e-06 25.9 0.1 3.2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBZ24246.1 - 0.00031 20.4 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBZ24246.1 - 0.0094 15.8 0.1 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 CBZ24246.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) DUF2407 PF10302.4 CBZ24246.1 - 0.11 12.7 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain EF-hand_7 PF13499.1 CBZ24247.1 - 9e-05 22.5 0.2 0.00033 20.7 0.1 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ24247.1 - 0.0014 18.3 0.1 0.012 15.4 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 CBZ24247.1 - 0.002 17.6 1.6 0.056 13.0 0.7 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ24247.1 - 0.0023 17.0 5.5 0.0046 16.1 0.0 3.1 3 0 0 3 3 3 1 EF hand EFhand_Ca_insen PF08726.5 CBZ24247.1 - 0.11 12.4 0.5 0.75 9.8 0.1 2.3 2 1 0 2 2 2 0 Ca2+ insensitive EF hand YokU PF14122.1 CBZ24247.1 - 0.32 10.7 3.7 2.5 7.8 0.7 2.5 1 1 0 2 2 2 0 YokU-like protein EF-hand_5 PF13202.1 CBZ24247.1 - 2.2 7.7 0.0 2.2 7.7 0.0 2.9 3 0 0 3 3 3 0 EF hand EF-hand_1 PF00036.27 CBZ24248.1 - 5.9e-43 140.9 12.3 2e-10 39.2 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ24248.1 - 2.5e-38 130.0 4.2 2.2e-21 75.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBZ24248.1 - 2.2e-33 113.6 11.2 2.3e-16 59.1 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBZ24248.1 - 2e-31 105.0 6.7 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBZ24248.1 - 2.9e-29 99.0 8.0 1.7e-07 30.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CBZ24248.1 - 8.6e-15 54.4 0.1 7.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBZ24248.1 - 1.1e-09 37.9 0.9 4.5e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBZ24248.1 - 3e-08 33.6 0.0 0.00049 20.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CBZ24248.1 - 1.9e-06 27.3 1.8 0.18 11.4 0.0 3.9 4 1 1 5 5 5 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CBZ24248.1 - 4.8e-06 26.4 1.2 5.9e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 CBZ24248.1 - 0.00022 20.9 0.3 0.082 12.6 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 CBZ24248.1 - 0.00025 20.6 0.1 0.013 15.0 0.1 2.5 1 1 0 1 1 1 1 Caleosin related protein EF-hand_like PF09279.6 CBZ24248.1 - 0.00033 20.6 1.2 0.0031 17.5 0.1 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_Rpb4 PF03874.11 CBZ24248.1 - 0.0038 17.2 0.5 1.7 8.6 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.6 CBZ24248.1 - 0.0051 16.2 1.1 0.0059 16.0 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) MotA_activ PF09114.5 CBZ24248.1 - 0.021 14.5 0.1 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 CBZ24248.1 - 0.042 13.6 0.2 11 5.8 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein LNS2 PF08235.8 CBZ24248.1 - 0.045 13.3 0.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 CBZ24248.1 - 0.064 12.8 0.1 0.95 8.9 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 CBZ24248.1 - 0.065 13.5 0.8 14 6.0 0.3 2.6 1 1 2 3 3 3 0 Toprim-like SpoVIF PF14069.1 CBZ24248.1 - 0.077 12.7 0.8 1.6 8.5 0.1 2.6 3 0 0 3 3 3 0 Stage VI sporulation protein F DUF1880 PF08976.6 CBZ24248.1 - 0.13 12.3 0.0 0.84 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) EF-hand_1 PF00036.27 CBZ24249.1 - 5.9e-43 140.9 12.3 2e-10 39.2 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ24249.1 - 2.5e-38 130.0 4.2 2.2e-21 75.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBZ24249.1 - 2.2e-33 113.6 11.2 2.3e-16 59.1 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBZ24249.1 - 2e-31 105.0 6.7 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBZ24249.1 - 2.9e-29 99.0 8.0 1.7e-07 30.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CBZ24249.1 - 8.6e-15 54.4 0.1 7.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBZ24249.1 - 1.1e-09 37.9 0.9 4.5e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBZ24249.1 - 3e-08 33.6 0.0 0.00049 20.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CBZ24249.1 - 1.9e-06 27.3 1.8 0.18 11.4 0.0 3.9 4 1 1 5 5 5 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CBZ24249.1 - 4.8e-06 26.4 1.2 5.9e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 CBZ24249.1 - 0.00022 20.9 0.3 0.082 12.6 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 CBZ24249.1 - 0.00025 20.6 0.1 0.013 15.0 0.1 2.5 1 1 0 1 1 1 1 Caleosin related protein EF-hand_like PF09279.6 CBZ24249.1 - 0.00033 20.6 1.2 0.0031 17.5 0.1 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_Rpb4 PF03874.11 CBZ24249.1 - 0.0038 17.2 0.5 1.7 8.6 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.6 CBZ24249.1 - 0.0051 16.2 1.1 0.0059 16.0 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) MotA_activ PF09114.5 CBZ24249.1 - 0.021 14.5 0.1 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 CBZ24249.1 - 0.042 13.6 0.2 11 5.8 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein LNS2 PF08235.8 CBZ24249.1 - 0.045 13.3 0.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 CBZ24249.1 - 0.064 12.8 0.1 0.95 8.9 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 CBZ24249.1 - 0.065 13.5 0.8 14 6.0 0.3 2.6 1 1 2 3 3 3 0 Toprim-like SpoVIF PF14069.1 CBZ24249.1 - 0.077 12.7 0.8 1.6 8.5 0.1 2.6 3 0 0 3 3 3 0 Stage VI sporulation protein F DUF1880 PF08976.6 CBZ24249.1 - 0.13 12.3 0.0 0.84 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) EF-hand_1 PF00036.27 CBZ24250.1 - 5.9e-43 140.9 12.3 2e-10 39.2 0.7 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ24250.1 - 2.5e-38 130.0 4.2 2.2e-21 75.7 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CBZ24250.1 - 2.2e-33 113.6 11.2 2.3e-16 59.1 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 CBZ24250.1 - 2e-31 105.0 6.7 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBZ24250.1 - 2.9e-29 99.0 8.0 1.7e-07 30.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CBZ24250.1 - 8.6e-15 54.4 0.1 7.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBZ24250.1 - 1.1e-09 37.9 0.9 4.5e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBZ24250.1 - 3e-08 33.6 0.0 0.00049 20.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CBZ24250.1 - 1.9e-06 27.3 1.8 0.18 11.4 0.0 3.9 4 1 1 5 5 5 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 CBZ24250.1 - 4.8e-06 26.4 1.2 5.9e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 CBZ24250.1 - 0.00022 20.9 0.3 0.082 12.6 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 CBZ24250.1 - 0.00025 20.6 0.1 0.013 15.0 0.1 2.5 1 1 0 1 1 1 1 Caleosin related protein EF-hand_like PF09279.6 CBZ24250.1 - 0.00033 20.6 1.2 0.0031 17.5 0.1 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like RNA_pol_Rpb4 PF03874.11 CBZ24250.1 - 0.0038 17.2 0.5 1.7 8.6 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF1103 PF06513.6 CBZ24250.1 - 0.0051 16.2 1.1 0.0059 16.0 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) MotA_activ PF09114.5 CBZ24250.1 - 0.021 14.5 0.1 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 CBZ24250.1 - 0.042 13.6 0.2 11 5.8 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein LNS2 PF08235.8 CBZ24250.1 - 0.045 13.3 0.1 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) Tenui_NCP PF04876.7 CBZ24250.1 - 0.064 12.8 0.1 0.95 8.9 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 CBZ24250.1 - 0.065 13.5 0.8 14 6.0 0.3 2.6 1 1 2 3 3 3 0 Toprim-like SpoVIF PF14069.1 CBZ24250.1 - 0.077 12.7 0.8 1.6 8.5 0.1 2.6 3 0 0 3 3 3 0 Stage VI sporulation protein F DUF1880 PF08976.6 CBZ24250.1 - 0.13 12.3 0.0 0.84 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF3441 PF11923.3 CBZ24251.1 - 2.1e-32 111.0 1.9 5.1e-31 106.5 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 CBZ24251.1 - 6.9e-32 110.5 6.1 2.5e-23 82.3 0.0 2.6 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 CBZ24251.1 - 9.6e-06 25.3 0.0 0.0002 21.1 0.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF814) SLA_LP_auto_ag PF05889.8 CBZ24252.1 - 1.9e-92 309.7 0.0 1.6e-52 178.3 0.0 3.6 3 1 0 3 3 3 3 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 CBZ24252.1 - 3.6e-05 23.0 0.0 7.2e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Beta-eliminating lyase DUF3783 PF12646.2 CBZ24252.1 - 0.05 13.3 0.1 10 5.9 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3783) DUF3854 PF12965.2 CBZ24252.1 - 0.14 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Reo_sigma1 PF01664.11 CBZ24253.1 - 0.066 12.2 0.2 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Reovirus viral attachment protein sigma 1 EF1G PF00647.14 CBZ24254.1 - 2.6e-46 155.7 0.1 8.8e-46 154.0 0.1 1.9 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CBZ24254.1 - 2.2e-12 46.8 1.0 7.7e-12 45.0 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CBZ24254.1 - 8.9e-09 35.4 0.0 2.7e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CBZ24254.1 - 1.7e-05 24.9 0.0 4.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CBZ24254.1 - 4.4e-05 23.2 0.1 0.00015 21.5 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBZ24254.1 - 0.00013 22.3 0.1 0.00013 22.3 0.1 2.7 3 1 1 4 4 4 1 Glutathione S-transferase, C-terminal domain Chorein_N PF12624.2 CBZ24256.1 - 1.4e-21 76.2 0.0 2.7e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter PUB PF09409.5 CBZ24257.1 - 1.3e-12 47.3 0.0 2.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 PUB domain CDC50 PF03381.10 CBZ24259.1 - 4.4e-80 268.8 0.1 6.4e-80 268.2 0.1 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Retinal PF15449.1 CBZ24259.1 - 0.39 8.3 9.0 0.48 8.0 6.3 1.1 1 0 0 1 1 1 0 Retinal protein Cep57_CLD_2 PF14197.1 CBZ24260.1 - 0.42 10.5 19.0 0.18 11.7 4.1 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 CDC37_N PF03234.9 CBZ24260.1 - 0.76 10.0 4.4 1.8 8.8 2.4 2.1 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4140 PF13600.1 CBZ24260.1 - 1.1 9.7 17.6 5.2 7.5 0.4 3.4 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 CBZ24260.1 - 2.3 7.7 15.8 0.3 10.6 5.3 2.3 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 CBZ24260.1 - 5.2 6.1 9.8 24 4.0 0.1 2.6 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 CBZ24260.1 - 5.8 6.7 10.3 32 4.3 4.2 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Speriolin_N PF15058.1 CBZ24260.1 - 9.8 6.0 12.5 1.1 9.0 0.4 2.9 2 1 0 2 2 2 0 Speriolin N terminus LCAT PF02450.10 CBZ24261.1 - 1.2e-44 152.9 0.0 4.7e-32 111.4 0.1 2.1 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CBZ24261.1 - 4.6e-05 23.4 0.4 0.00011 22.1 0.3 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ24261.1 - 0.004 16.9 0.1 0.0072 16.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Motile_Sperm PF00635.21 CBZ24262.1 - 3.8e-11 42.5 0.0 6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain SHS2_Rpb7-N PF03876.12 CBZ24263.1 - 1.6e-24 85.8 0.0 2.6e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 CBZ24263.1 - 2.6e-11 43.7 0.0 6.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 RNA polymerase III subunit Rpc25 GTP_EFTU PF00009.22 CBZ24264.1 - 3.6e-35 121.1 0.0 6.3e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CBZ24264.1 - 2.6e-29 101.1 0.6 6.5e-29 99.8 0.1 2.0 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal MMR_HSR1 PF01926.18 CBZ24264.1 - 9.9e-05 22.2 0.0 0.00052 19.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CBZ24264.1 - 0.00047 20.2 3.5 0.00078 19.5 1.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu domain 2 Dynamin_N PF00350.18 CBZ24264.1 - 0.022 14.5 0.1 0.55 10.0 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Zn-ribbon_8 PF09723.5 CBZ24264.1 - 0.075 12.9 4.6 0.17 11.8 3.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain NOB1_Zn_bind PF08772.6 CBZ24264.1 - 0.23 11.2 1.7 0.61 9.9 1.2 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like GTP_EFTU PF00009.22 CBZ24265.1 - 1.4e-35 122.3 0.0 2.3e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CBZ24265.1 - 8.7e-12 44.9 0.1 1.9e-10 40.6 0.0 2.8 3 0 0 3 3 3 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CBZ24265.1 - 0.00023 21.2 1.3 0.0033 17.5 0.9 2.5 1 1 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ24265.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zn-ribbon_8 PF09723.5 CBZ24265.1 - 0.11 12.4 4.6 0.22 11.4 3.2 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Dynamin_N PF00350.18 CBZ24265.1 - 0.11 12.2 0.0 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Myosin_tail_1 PF01576.14 CBZ24266.1 - 0.00024 18.9 13.5 0.00033 18.5 9.3 1.1 1 0 0 1 1 1 1 Myosin tail DUF4201 PF13870.1 CBZ24266.1 - 0.00053 19.4 10.7 0.04 13.3 1.5 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) WEMBL PF05701.6 CBZ24266.1 - 0.0075 14.7 17.2 0.0087 14.5 11.5 1.2 1 1 0 1 1 1 1 Weak chloroplast movement under blue light CALCOCO1 PF07888.6 CBZ24266.1 - 0.02 13.1 8.3 0.025 12.8 5.7 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Acyl_transf_1 PF00698.16 CBZ24266.1 - 0.027 13.7 0.4 0.037 13.3 0.3 1.2 1 0 0 1 1 1 0 Acyl transferase domain HR1 PF02185.11 CBZ24266.1 - 0.035 13.8 9.2 0.17 11.6 1.0 2.9 3 0 0 3 3 3 0 Hr1 repeat CCDC-167 PF15188.1 CBZ24266.1 - 0.086 12.7 5.8 2.5 8.1 0.2 2.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 HALZ PF02183.13 CBZ24266.1 - 0.12 12.0 9.0 27 4.5 0.1 4.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 CBZ24266.1 - 0.15 11.1 8.0 0.17 11.0 3.8 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Scaffolding_pro PF11418.3 CBZ24266.1 - 0.19 12.0 5.6 1.7 8.9 3.2 2.3 2 1 0 2 2 2 0 Phi29 scaffolding protein DivIVA PF05103.8 CBZ24266.1 - 0.39 10.7 14.6 10 6.1 4.6 3.2 2 1 1 3 3 3 0 DivIVA protein Cep57_CLD_2 PF14197.1 CBZ24266.1 - 0.5 10.3 14.6 0.11 12.5 2.4 3.4 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 IncA PF04156.9 CBZ24266.1 - 0.53 9.8 14.9 0.6 9.6 9.4 1.8 1 1 0 1 1 1 0 IncA protein Spectrin PF00435.16 CBZ24266.1 - 0.54 10.5 14.1 8 6.8 1.9 3.0 2 1 1 3 3 3 0 Spectrin repeat Kinetocho_Slk19 PF12709.2 CBZ24266.1 - 0.6 10.2 8.4 3.6 7.7 0.2 3.7 2 1 2 4 4 4 0 Central kinetochore-associated Microtub_assoc PF07989.6 CBZ24266.1 - 0.91 9.3 6.4 3.6 7.4 0.5 2.8 3 0 0 3 3 2 0 Microtubule associated DUF1151 PF06625.6 CBZ24266.1 - 0.94 9.2 12.6 0.77 9.5 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1151) TBPIP PF07106.8 CBZ24266.1 - 1.2 8.7 12.1 1.2 8.6 1.6 3.2 2 2 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) V_ATPase_I PF01496.14 CBZ24266.1 - 1.3 6.7 6.4 1.5 6.5 4.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ERM PF00769.14 CBZ24266.1 - 1.8 8.0 19.4 2.1 7.7 3.3 3.0 2 1 1 3 3 3 0 Ezrin/radixin/moesin family SlyX PF04102.7 CBZ24266.1 - 1.9 8.9 10.2 27 5.2 0.8 3.6 2 1 2 4 4 4 0 SlyX Exonuc_VII_L PF02601.10 CBZ24266.1 - 1.9 7.5 8.9 2.6 7.1 6.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.2 CBZ24266.1 - 2.7 7.8 16.9 21 4.9 10.8 2.5 2 1 0 2 2 2 0 Tropomyosin like FliD_N PF02465.13 CBZ24266.1 - 3.8 7.9 13.8 1.8 8.9 2.3 3.1 1 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Occludin_ELL PF07303.8 CBZ24266.1 - 4.7 8.0 8.5 15 6.4 2.4 2.7 2 1 0 2 2 2 0 Occludin homology domain AAA_13 PF13166.1 CBZ24266.1 - 5.8 5.2 10.9 10 4.4 6.6 1.6 1 1 0 1 1 1 0 AAA domain Fzo_mitofusin PF04799.8 CBZ24266.1 - 6.1 6.1 9.1 12 5.2 1.2 2.9 1 1 2 3 3 3 0 fzo-like conserved region Seryl_tRNA_N PF02403.17 CBZ24266.1 - 6.2 6.8 14.2 0.55 10.2 1.7 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.6 CBZ24266.1 - 6.3 6.7 8.0 11 5.9 0.4 2.9 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Nup54 PF13874.1 CBZ24266.1 - 6.6 6.3 11.7 4.9 6.8 2.0 2.6 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Atg14 PF10186.4 CBZ24266.1 - 8.1 5.2 14.8 3.6 6.4 2.0 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4570 PF15134.1 CBZ24266.1 - 8.4 6.2 10.4 10 6.0 1.4 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4570) DUF2681 PF10883.3 CBZ24266.1 - 8.7 6.6 10.8 0.44 10.7 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) DUF2315 PF10231.4 CBZ24267.1 - 0.39 10.5 3.5 2.4 8.0 2.4 2.1 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2315) MRP PF09387.5 CBZ24268.1 - 2.3e-73 246.0 2.8 2.8e-73 245.7 2.0 1.1 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Tim17 PF02466.14 CBZ24269.1 - 5.8e-17 61.9 9.0 7.2e-17 61.6 6.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cytochrom_B_N PF00033.14 CBZ24269.1 - 0.011 15.0 0.9 0.014 14.7 0.6 1.1 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB CENP-H PF05837.7 CBZ24271.1 - 4.6 7.4 6.8 24 5.1 0.2 3.1 3 1 1 4 4 4 0 Centromere protein H (CENP-H) PTH2 PF01981.11 CBZ24272.1 - 0.015 15.0 0.5 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase PTH2 RRM_1 PF00076.17 CBZ24272.1 - 0.12 12.0 0.2 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Skp1 PF01466.14 CBZ24273.1 - 0.00054 19.9 3.6 0.0034 17.3 2.5 2.1 1 1 0 1 1 1 1 Skp1 family, dimerisation domain Skp1 PF01466.14 CBZ24274.1 - 0.085 12.8 0.1 0.27 11.3 0.1 1.8 1 1 0 1 1 1 0 Skp1 family, dimerisation domain Ank_2 PF12796.2 CBZ24276.1 - 9e-05 22.7 0.2 0.0096 16.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBZ24276.1 - 0.00013 22.0 1.3 0.0081 16.3 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 CBZ24276.1 - 0.0021 17.7 0.1 0.0021 17.7 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CBZ24276.1 - 0.0056 17.1 1.4 0.081 13.4 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ24276.1 - 0.02 15.0 0.5 0.67 10.3 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeat zf-C3HC4_3 PF13920.1 CBZ24277.1 - 4.5e-10 39.0 24.6 4.5e-10 39.0 17.0 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA PF00004.24 CBZ24278.1 - 2.7e-32 111.7 0.0 5.6e-22 78.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ24278.1 - 1.1e-08 35.3 0.3 7.8e-05 22.8 0.0 3.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ24278.1 - 2.6e-08 33.5 0.0 0.00016 21.3 0.0 3.5 2 0 0 2 2 2 2 Part of AAA domain Zot PF05707.7 CBZ24278.1 - 9.2e-07 28.5 0.9 0.038 13.4 0.0 4.0 2 2 0 2 2 2 2 Zonular occludens toxin (Zot) AAA_33 PF13671.1 CBZ24278.1 - 1e-06 28.7 0.0 0.0055 16.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 CBZ24278.1 - 1.1e-06 28.7 5.9 5.3e-06 26.5 0.0 3.8 3 2 1 4 4 4 1 AAA ATPase domain AAA_14 PF13173.1 CBZ24278.1 - 2e-06 27.7 0.0 0.00015 21.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CBZ24278.1 - 7.7e-05 22.1 0.0 0.0048 16.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 CBZ24278.1 - 7.9e-05 23.4 0.0 0.013 16.2 0.0 3.1 3 0 0 3 3 2 1 AAA domain DUF2075 PF09848.4 CBZ24278.1 - 0.0001 21.4 0.1 0.62 8.9 0.0 3.3 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 CBZ24278.1 - 0.00013 21.6 0.0 0.0082 15.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CBZ24278.1 - 0.00014 20.7 0.1 0.037 12.7 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus RNA_helicase PF00910.17 CBZ24278.1 - 0.00023 21.2 0.0 0.046 13.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 CBZ24278.1 - 0.00087 18.9 0.1 0.037 13.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Bac_DnaA PF00308.13 CBZ24278.1 - 0.0014 18.3 0.1 0.0052 16.4 0.0 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_30 PF13604.1 CBZ24278.1 - 0.002 17.7 0.1 0.13 11.7 0.1 2.9 2 0 0 2 2 2 1 AAA domain Torsin PF06309.6 CBZ24278.1 - 0.0046 16.8 0.2 0.12 12.2 0.1 2.5 2 0 0 2 2 2 1 Torsin AAA_25 PF13481.1 CBZ24278.1 - 0.0059 16.0 0.0 0.36 10.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 CBZ24278.1 - 0.0066 15.9 0.6 0.61 9.5 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CBZ24278.1 - 0.0074 15.4 0.2 0.049 12.7 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CBZ24278.1 - 0.0081 15.2 0.0 0.085 11.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 CBZ24278.1 - 0.0086 16.3 0.4 0.12 12.7 0.0 2.8 3 0 0 3 3 2 1 ABC transporter AAA_18 PF13238.1 CBZ24278.1 - 0.01 16.1 0.0 0.76 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CBZ24278.1 - 0.014 14.5 1.2 0.1 11.8 0.0 2.7 2 1 0 3 3 3 0 PhoH-like protein AAA_2 PF07724.9 CBZ24278.1 - 0.033 14.0 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) APS_kinase PF01583.15 CBZ24278.1 - 0.035 13.7 0.1 0.34 10.5 0.0 2.5 3 0 0 3 3 2 0 Adenylylsulphate kinase DUF3135 PF11333.3 CBZ24278.1 - 0.037 14.1 0.3 0.19 11.9 0.1 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF3135) DUF258 PF03193.11 CBZ24278.1 - 0.043 13.0 0.1 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DEAD PF00270.24 CBZ24278.1 - 0.052 13.0 0.1 2 7.8 0.0 2.7 3 0 0 3 3 2 0 DEAD/DEAH box helicase AAA_10 PF12846.2 CBZ24278.1 - 0.1 12.0 4.6 6.3 6.1 0.1 3.5 2 2 2 4 4 4 0 AAA-like domain KaiC PF06745.8 CBZ24278.1 - 0.1 11.6 0.2 3.7 6.5 0.0 2.5 2 0 0 2 2 2 0 KaiC SRP54 PF00448.17 CBZ24278.1 - 0.1 11.9 0.2 0.69 9.3 0.0 2.4 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain MobB PF03205.9 CBZ24278.1 - 0.11 12.1 0.0 0.34 10.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 CBZ24278.1 - 0.13 11.1 0.0 0.29 9.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Guanylate_kin PF00625.16 CBZ24278.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase ResIII PF04851.10 CBZ24278.1 - 0.13 12.0 0.0 0.5 10.1 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UPF0079 PF02367.12 CBZ24278.1 - 0.17 11.5 0.5 0.66 9.6 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 CBZ24278.1 - 0.18 11.3 1.0 5.6 6.5 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CBZ24278.1 - 0.58 10.4 0.3 1.8 8.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain zf-CCHC_4 PF14392.1 CBZ24279.1 - 0.28 10.9 0.9 0.51 10.0 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle AAA_12 PF13087.1 CBZ24280.1 - 1.7e-49 167.9 0.0 2.7e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CBZ24280.1 - 1e-35 123.4 0.2 5.4e-35 121.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ24280.1 - 4.6e-07 29.4 0.7 4.6e-07 29.4 0.5 4.0 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 CBZ24280.1 - 0.0022 18.1 0.0 0.025 14.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CBZ24280.1 - 0.09 12.5 0.0 0.91 9.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 CBZ24280.1 - 0.21 10.8 0.0 0.21 10.8 0.0 2.7 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain Bromodomain PF00439.20 CBZ24282.1 - 1.6e-19 69.6 0.0 5.8e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 Bromodomain Mito_carr PF00153.22 CBZ24283.1 - 6.2e-45 150.8 6.8 6.8e-17 60.9 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Orthopox_C10L PF07020.6 CBZ24283.1 - 1.2 9.7 7.1 0.74 10.3 2.0 2.2 2 0 0 2 2 2 0 Orthopoxvirus C10L protein DZR PF12773.2 CBZ24284.1 - 0.0047 16.7 2.7 0.14 11.9 0.0 3.2 2 1 1 3 3 3 1 Double zinc ribbon HypA PF01155.14 CBZ24284.1 - 0.028 14.0 0.7 1.6 8.4 0.0 2.6 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-DNL PF05180.7 CBZ24284.1 - 0.21 11.3 0.8 21 4.9 0.6 2.9 2 1 0 2 2 2 0 DNL zinc finger zf-FPG_IleRS PF06827.9 CBZ24284.1 - 0.46 10.1 3.8 17 5.1 0.1 3.0 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DUF2296 PF10058.4 CBZ24284.1 - 0.88 9.3 5.2 7.4 6.4 0.1 3.8 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) zf-ribbon_3 PF13248.1 CBZ24284.1 - 0.97 8.7 4.8 40 3.6 0.0 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Kelch_4 PF13418.1 CBZ24285.1 - 1.8e-11 43.6 1.2 0.75 9.6 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ24285.1 - 5.7e-06 26.1 7.3 0.17 11.8 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBZ24285.1 - 0.00076 19.1 2.1 12 5.8 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_1 PF01344.20 CBZ24285.1 - 0.0025 17.3 0.5 32 4.1 0.0 4.6 5 0 0 5 5 5 0 Kelch motif Kelch_6 PF13964.1 CBZ24285.1 - 0.004 17.2 0.0 59 4.0 0.0 4.7 5 0 0 5 5 5 0 Kelch motif Kelch_3 PF13415.1 CBZ24285.1 - 0.074 13.2 22.1 0.69 10.1 0.0 6.5 6 1 0 6 6 6 0 Galactose oxidase, central domain Peptidase_C97 PF05903.9 CBZ24286.1 - 9.7e-25 87.1 0.1 4.3e-24 85.0 0.0 1.7 1 1 1 2 2 2 1 PPPDE putative peptidase domain LRAT PF04970.8 CBZ24286.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Peptidase_C97 PF05903.9 CBZ24287.1 - 5.9e-21 74.8 0.0 8.1e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF2629 PF10945.3 CBZ24288.1 - 0.43 9.9 2.0 12 5.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2629) Flagellar_rod PF05149.7 CBZ24289.1 - 1.7e-96 322.8 20.0 1.7e-96 322.8 13.9 1.8 2 0 0 2 2 2 1 Paraflagellar rod protein Glutaredoxin2_C PF04399.8 CBZ24289.1 - 0.17 11.4 5.4 0.17 11.4 0.5 3.0 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Tweety PF04906.8 CBZ24289.1 - 1.3 7.3 4.5 4.9 5.4 0.7 2.4 2 0 0 2 2 2 0 Tweety Histone PF00125.19 CBZ24291.1 - 2.7e-16 59.4 0.9 3.8e-16 58.9 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ24291.1 - 0.0022 18.0 0.2 0.0048 16.9 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DNA_photolyase PF00875.13 CBZ24291.1 - 0.0023 17.7 0.1 0.0027 17.4 0.1 1.0 1 0 0 1 1 1 1 DNA photolyase GMP_synt_C PF00958.17 CBZ24291.1 - 0.057 13.1 0.9 0.1 12.3 0.3 1.5 1 1 1 2 2 2 0 GMP synthase C terminal domain Glyco_hydro_47 PF01532.15 CBZ24297.1 - 5.3e-06 25.3 0.0 1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 InaF-motif PF15018.1 CBZ24297.1 - 2.6 7.5 6.6 5 6.6 4.5 1.4 1 0 0 1 1 1 0 TRP-interacting helix SET PF00856.23 CBZ24298.1 - 7.6e-08 32.8 0.0 2.7e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 SET domain CENP-N PF05238.8 CBZ24299.1 - 0.0013 17.8 6.3 0.0015 17.6 4.3 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Trigger_C PF05698.9 CBZ24299.1 - 0.0084 15.9 3.7 0.0084 15.9 2.6 2.0 1 1 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus DUF1318 PF07027.7 CBZ24299.1 - 0.046 13.9 0.9 0.046 13.9 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1318) SurA_N PF09312.6 CBZ24299.1 - 0.075 12.8 1.9 0.12 12.2 1.3 1.4 1 1 0 1 1 1 0 SurA N-terminal domain Med8 PF10232.4 CBZ24299.1 - 0.19 11.1 6.8 0.23 10.9 4.7 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 DUF1128 PF06569.6 CBZ24299.1 - 0.28 10.9 3.7 1.7 8.4 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1128) DUF4168 PF13767.1 CBZ24299.1 - 0.45 11.1 3.5 1.1 9.9 2.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4168) DUF1664 PF07889.7 CBZ24299.1 - 0.46 10.2 5.6 0.66 9.7 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) EURL PF06937.6 CBZ24299.1 - 0.51 9.6 5.6 0.8 9.0 3.3 1.5 1 1 0 1 1 1 0 EURL protein L31 PF09784.4 CBZ24299.1 - 0.71 9.9 5.8 0.43 10.6 2.8 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 DDHD PF02862.12 CBZ24299.1 - 1.9 8.2 5.1 2.4 7.8 3.5 1.2 1 0 0 1 1 1 0 DDHD domain GAS PF13851.1 CBZ24299.1 - 2.3 7.3 14.2 0.069 12.3 5.6 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.1 CBZ24299.1 - 3.1 6.6 9.3 4 6.3 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Coq4 PF05019.8 CBZ24300.1 - 4.9e-54 182.5 0.0 5.5e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DnaJ PF00226.26 CBZ24301.1 - 9.6e-13 47.6 0.1 1.8e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain GcrA PF07750.6 CBZ24301.1 - 0.0052 17.0 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 GcrA cell cycle regulator Rhodanese PF00581.15 CBZ24302.1 - 2.1e-05 24.7 0.0 2.7e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.15 CBZ24303.1 - 1.8e-14 54.0 0.0 2.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.15 CBZ24304.1 - 1.4e-18 67.2 0.0 1.6e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Tet_JBP PF12851.2 CBZ24305.1 - 2.6e-23 82.1 0.0 5.5e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Cyt-b5 PF00173.23 CBZ24306.1 - 2.8e-19 68.6 0.3 3.6e-19 68.3 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Laminin_G_3 PF13385.1 CBZ24309.1 - 4.9e-07 30.1 0.0 0.0027 17.9 0.0 2.3 2 0 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.19 CBZ24309.1 - 9.1e-05 22.4 0.0 0.27 11.2 0.0 3.0 3 0 0 3 3 3 2 Laminin G domain IQ PF00612.22 CBZ24309.1 - 0.014 14.9 0.9 0.083 12.5 0.0 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif LRR_6 PF13516.1 CBZ24310.1 - 2e-14 51.9 0.5 0.029 14.4 0.1 7.2 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 CBZ24310.1 - 0.029 14.0 0.0 3.9 7.2 0.0 3.4 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) EF-hand_6 PF13405.1 CBZ24311.1 - 0.003 17.3 0.0 0.51 10.3 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain RIIa PF02197.12 CBZ24311.1 - 0.037 13.4 0.0 0.084 12.3 0.0 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit EF-hand_7 PF13499.1 CBZ24311.1 - 0.11 12.7 0.0 0.19 11.8 0.0 1.5 1 1 0 1 1 1 0 EF-hand domain pair ADIP PF11559.3 CBZ24312.1 - 0.13 12.1 92.0 0.053 13.4 7.4 7.7 2 2 4 7 7 7 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 CBZ24312.1 - 0.18 12.0 0.2 0.18 12.0 0.1 8.9 4 2 1 5 5 5 0 Protein of unknown function (DUF904) PHO4 PF01384.15 CBZ24314.1 - 1.2e-103 346.2 9.2 2.3e-103 345.3 6.4 1.4 1 1 0 1 1 1 1 Phosphate transporter family Gryzun PF07919.7 CBZ24315.1 - 1.5e-48 165.4 0.0 2e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi MMS19_N PF14500.1 CBZ24316.1 - 5.9e-32 110.9 4.3 1.9e-31 109.2 1.5 2.5 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.3 CBZ24316.1 - 0.0023 17.3 1.6 0.007 15.7 0.1 2.5 3 0 0 3 3 3 1 CLASP N terminal Thymidylate_kin PF02223.12 CBZ24317.1 - 2e-14 53.3 0.0 7.3e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 Thymidylate kinase CbiD PF01888.12 CBZ24317.1 - 0.12 11.2 0.1 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 CbiD Ribosomal_L35Ae PF01247.13 CBZ24318.1 - 3.4e-35 119.7 1.6 4.6e-35 119.2 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CBZ24318.1 - 7.3e-05 22.6 0.7 0.097 12.6 0.1 2.6 2 1 0 2 2 2 2 RimM N-terminal domain adh_short PF00106.20 CBZ24320.1 - 2.2e-16 60.2 0.1 5.5e-16 58.9 0.1 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CBZ24320.1 - 1.9e-07 30.7 0.0 2.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CBZ24320.1 - 1.7e-06 27.8 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBZ24320.1 - 1.4e-05 25.0 0.0 2.1e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CBZ24320.1 - 0.0013 18.8 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding SRP40_C PF05022.7 CBZ24321.1 - 8.7e-07 29.3 0.3 1.6e-06 28.4 0.2 1.5 1 0 0 1 1 1 1 SRP40, C-terminal domain WD40 PF00400.27 CBZ24322.1 - 1.1e-45 151.9 29.1 2.1e-10 40.0 0.7 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat PSP1 PF04468.7 CBZ24323.1 - 5e-25 87.2 0.3 7.7e-25 86.7 0.2 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Seryl_tRNA_N PF02403.17 CBZ24324.1 - 0.0047 16.9 6.1 0.0047 16.9 4.2 3.1 2 1 1 3 3 3 1 Seryl-tRNA synthetase N-terminal domain CCDC155 PF14662.1 CBZ24324.1 - 0.043 13.3 11.2 0.1 12.2 7.8 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 BLOC1_2 PF10046.4 CBZ24324.1 - 0.045 13.8 7.6 1.4 9.1 1.5 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 STAT_alpha PF01017.15 CBZ24324.1 - 0.078 12.6 6.5 0.19 11.4 4.5 1.6 1 0 0 1 1 1 0 STAT protein, all-alpha domain FlxA PF14282.1 CBZ24324.1 - 0.21 11.5 12.7 0.64 9.9 4.3 2.8 1 1 1 2 2 2 0 FlxA-like protein AAA_13 PF13166.1 CBZ24324.1 - 0.98 7.7 5.8 1.3 7.4 4.0 1.2 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 CBZ24324.1 - 1.1 8.2 5.9 2 7.3 4.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Spectrin PF00435.16 CBZ24324.1 - 1.9 8.8 14.0 6.4 7.1 2.0 3.3 2 1 1 3 3 3 0 Spectrin repeat NPV_P10 PF05531.7 CBZ24324.1 - 2.3 8.5 7.0 4.8e+02 1.0 4.8 2.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 CBZ24324.1 - 2.7 7.5 9.2 0.92 9.0 3.8 2.0 2 0 0 2 2 2 0 IncA protein DEAD PF00270.24 CBZ24325.1 - 1.8e-16 60.0 0.2 1.5e-12 47.3 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ24325.1 - 2.4e-12 46.5 0.0 5.7e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CBZ24325.1 - 2.9e-05 22.6 0.0 0.011 14.1 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1253) DUF4250 PF14056.1 CBZ24327.1 - 0.028 14.1 1.2 0.14 11.9 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) Ribosomal_S15 PF00312.17 CBZ24327.1 - 0.12 12.1 7.6 0.3 10.8 5.1 1.8 1 1 0 1 1 1 0 Ribosomal protein S15 CTP_synth_N PF06418.9 CBZ24327.1 - 0.38 9.7 1.5 0.6 9.1 1.1 1.2 1 0 0 1 1 1 0 CTP synthase N-terminus Cupin_8 PF13621.1 CBZ24327.1 - 1.6 8.1 4.1 0.62 9.5 0.5 1.9 2 0 0 2 2 2 0 Cupin-like domain APG6 PF04111.7 CBZ24327.1 - 1.6 7.6 33.5 0.4 9.6 12.5 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 NPV_P10 PF05531.7 CBZ24327.1 - 2.2 8.6 11.8 1 9.6 3.2 3.3 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Sin3_corepress PF08295.7 CBZ24327.1 - 8.6 6.1 10.6 1 9.1 2.8 2.6 2 1 1 3 3 3 0 Sin3 family co-repressor Spc7 PF08317.6 CBZ24327.1 - 9.7 4.7 29.5 0.24 10.0 12.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein GDA1_CD39 PF01150.12 CBZ24328.1 - 2.2e-57 194.4 0.0 2.1e-56 191.2 0.0 2.0 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CBZ24328.1 - 0.011 14.9 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family LRR_4 PF12799.2 CBZ24329.1 - 2.3e-15 55.8 11.4 8e-06 25.3 2.1 3.5 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24329.1 - 5.7e-15 54.8 34.9 9.7e-07 28.4 4.9 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBZ24329.1 - 8.5e-11 40.3 9.6 0.52 10.5 0.1 6.1 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 CBZ24329.1 - 5.4e-07 28.7 11.1 7 7.3 0.3 5.8 5 0 0 5 5 5 4 Leucine rich repeat LRR_6 PF13516.1 CBZ24329.1 - 4.9e-05 22.9 7.5 8.3 6.8 0.1 5.4 5 0 0 5 5 5 2 Leucine Rich repeat PDZ_2 PF13180.1 CBZ24331.1 - 7.2e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBZ24331.1 - 0.00042 20.4 0.0 0.00089 19.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) MORN PF02493.15 CBZ24332.1 - 3.8e-18 64.0 14.2 2.1e-05 23.9 0.6 4.7 4 0 0 4 4 4 4 MORN repeat Pkinase PF00069.20 CBZ24333.1 - 1.9e-58 197.6 0.0 2.5e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24333.1 - 1.3e-27 96.5 0.0 2.2e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ24333.1 - 5e-06 25.7 0.7 1.1e-05 24.6 0.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ24333.1 - 0.00054 19.7 1.1 0.00054 19.7 0.8 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ24333.1 - 0.044 13.1 0.7 0.17 11.2 0.3 2.0 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 CBZ24333.1 - 0.1 12.1 0.2 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nop PF01798.13 CBZ24334.1 - 8e-56 187.5 0.2 1.4e-55 186.6 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CBZ24334.1 - 3.3e-22 78.0 0.0 6.9e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CBZ24334.1 - 1.2e-20 73.3 0.0 3.1e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Amastin PF07344.6 CBZ24337.1 - 9.6e-43 145.4 23.6 3e-27 95.1 4.3 2.2 2 0 0 2 2 2 2 Amastin surface glycoprotein DUF2165 PF09933.4 CBZ24337.1 - 0.12 12.0 16.6 0.046 13.4 5.3 2.9 2 1 1 3 3 3 0 Predicted small integral membrane protein (DUF2165) Amastin PF07344.6 CBZ24338.1 - 2.6e-60 202.5 19.3 1.7e-33 115.4 6.0 2.1 2 0 0 2 2 2 2 Amastin surface glycoprotein DUF1625 PF07787.7 CBZ24338.1 - 4.9 6.3 11.9 0.047 12.9 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1625) Pterin_4a PF01329.14 CBZ24340.1 - 8.9e-10 38.1 0.0 3.1e-08 33.2 0.0 2.2 1 1 1 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase HrpB_C PF08482.5 CBZ24340.1 - 0.043 13.9 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal COPI_assoc PF08507.5 CBZ24341.1 - 5.3e-06 26.1 19.4 6.9e-06 25.7 13.4 1.1 1 0 0 1 1 1 1 COPI associated protein RNase_T PF00929.19 CBZ24342.1 - 4.8e-19 69.2 0.0 7.9e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Iso_dh PF00180.15 CBZ24344.1 - 4.5e-73 246.2 0.0 5.1e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase LPP PF04728.8 CBZ24345.1 - 0.011 15.5 0.6 0.03 14.0 0.4 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Spc24 PF08286.6 CBZ24345.1 - 0.16 11.7 5.1 0.33 10.6 3.5 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 V_ATPase_I PF01496.14 CBZ24345.1 - 0.17 9.7 4.8 0.27 9.0 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.7 CBZ24345.1 - 0.23 11.8 13.7 0.31 11.4 5.8 3.2 3 0 0 3 3 3 0 SlyX Ead_Ea22 PF13935.1 CBZ24345.1 - 0.53 10.6 10.2 1.5 9.1 7.1 1.8 1 1 0 1 1 1 0 Ead/Ea22-like protein IncA PF04156.9 CBZ24345.1 - 0.74 9.3 8.8 1.4 8.4 6.1 1.4 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 CBZ24345.1 - 0.77 7.0 15.4 1.1 6.5 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DASH_Spc34 PF08657.5 CBZ24345.1 - 2.3 7.8 9.9 1.7 8.2 5.2 1.8 1 1 1 2 2 2 0 DASH complex subunit Spc34 Sugarporin_N PF11471.3 CBZ24345.1 - 2.7 7.7 9.5 2.2 7.9 4.6 2.2 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension Mnd1 PF03962.10 CBZ24345.1 - 3.9 7.0 10.5 7 6.2 7.3 1.3 1 0 0 1 1 1 0 Mnd1 family Atg14 PF10186.4 CBZ24345.1 - 5.6 5.8 11.1 10 4.9 7.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sec23_trunk PF04811.10 CBZ24346.1 - 1.7e-40 138.9 0.0 6e-20 71.6 0.0 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CBZ24346.1 - 1.9e-25 88.2 0.0 4.4e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CBZ24346.1 - 7.6e-19 68.0 0.0 1.4e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CBZ24346.1 - 5.4e-07 29.2 0.0 1.1e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 CBZ24346.1 - 0.045 13.3 9.2 0.1 12.1 6.3 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger ThiC PF01964.13 CBZ24346.1 - 0.073 11.5 3.1 0.31 9.4 0.0 2.1 2 0 0 2 2 2 0 ThiC family Abhydrolase_1 PF00561.15 CBZ24347.1 - 9.7e-05 22.0 0.0 0.00031 20.3 0.0 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAF1_ABF1 PF04684.8 CBZ24347.1 - 0.11 11.2 3.6 0.24 10.2 2.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor BT1 PF03092.11 CBZ24349.1 - 3.8e-149 497.1 8.4 4.5e-149 496.8 5.8 1.1 1 0 0 1 1 1 1 BT1 family BT1 PF03092.11 CBZ24350.1 - 1.3e-195 650.2 3.2 1.5e-195 650.0 2.3 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.11 CBZ24351.1 - 1.6e-189 630.1 5.3 1.8e-189 629.9 3.7 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.11 CBZ24352.1 - 1.7e-198 659.7 5.0 2e-198 659.4 3.4 1.0 1 0 0 1 1 1 1 BT1 family Dak1 PF02733.12 CBZ24353.1 - 8.7e-85 284.1 1.5 8.7e-85 284.1 1.0 1.6 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.12 CBZ24353.1 - 2.8e-36 124.8 4.1 6.9e-36 123.5 2.9 1.7 1 0 0 1 1 1 1 DAK2 domain POTRA_2 PF08479.6 CBZ24353.1 - 0.091 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type zf-C3HC4_3 PF13920.1 CBZ24355.1 - 7.8e-09 35.0 11.6 1.7e-08 34.0 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ24355.1 - 0.19 11.4 11.3 0.46 10.2 7.8 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBZ24355.1 - 0.99 9.4 12.2 3.5 7.7 8.6 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ24356.1 - 4.4e-10 39.0 10.9 6.8e-10 38.4 7.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ24356.1 - 0.01 15.5 11.5 0.02 14.6 8.0 1.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBZ24356.1 - 0.021 14.8 12.6 0.045 13.7 8.7 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) 4F5 PF04419.9 CBZ24357.1 - 6.5e-10 39.5 8.0 9.1e-10 39.1 5.6 1.2 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.2 CBZ24357.1 - 1.6e-07 31.2 0.3 1.6e-07 31.2 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding zf-C2H2_4 PF13894.1 CBZ24357.1 - 0.0062 16.7 1.1 0.038 14.3 0.2 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CBZ24357.1 - 0.0067 16.6 3.0 0.1 12.9 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-H2C2_5 PF13909.1 CBZ24357.1 - 1.3 9.3 4.8 0.66 10.3 0.7 2.3 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Peptidase_M8 PF01457.11 CBZ24358.1 - 1.2e-263 875.1 5.3 1.4e-263 874.9 3.7 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1025 PF06262.6 CBZ24358.1 - 0.0034 17.1 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 Possibl zinc metallo-peptidase Peptidase_M8 PF01457.11 CBZ24359.1 - 9.2e-258 855.7 3.4 1.1e-257 855.5 2.3 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1025 PF06262.6 CBZ24359.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Peptidase_M8 PF01457.11 CBZ24360.1 - 2.9e-258 857.4 5.3 3.3e-258 857.2 3.6 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1025 PF06262.6 CBZ24360.1 - 0.065 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Peptidase_M8 PF01457.11 CBZ24361.1 - 1.2e-259 861.9 7.7 1.4e-259 861.7 5.3 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1025 PF06262.6 CBZ24361.1 - 0.0034 17.1 0.0 0.0075 16.0 0.0 1.6 1 0 0 1 1 1 1 Possibl zinc metallo-peptidase Peptidase_M8 PF01457.11 CBZ24362.1 - 1.6e-259 861.6 3.8 1.8e-259 861.3 2.6 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1025 PF06262.6 CBZ24362.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Pkinase PF00069.20 CBZ24365.1 - 4e-65 219.5 0.0 4.7e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24365.1 - 6.4e-28 97.5 0.0 3.8e-27 94.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ24365.1 - 0.0064 15.4 0.0 0.0098 14.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBZ24365.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Baculo_11_kDa PF06143.6 CBZ24366.1 - 0.43 9.9 2.4 1 8.7 1.7 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Sarcoglycan_2 PF05510.8 CBZ24366.1 - 1.1 7.4 0.0 1.9 6.6 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF912 PF06024.7 CBZ24366.1 - 2.9 8.0 0.0 7.1 6.7 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) NAD_Gly3P_dh_N PF01210.18 CBZ24367.1 - 2.6e-50 170.1 0.0 4.2e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CBZ24367.1 - 6.8e-49 165.4 0.7 1.1e-48 164.7 0.5 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.9 CBZ24367.1 - 2e-05 24.0 0.0 3.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 CBZ24367.1 - 0.00036 20.9 0.0 0.00077 19.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CBZ24367.1 - 0.0019 18.0 0.0 0.0082 15.9 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1188 PF06690.6 CBZ24367.1 - 0.016 14.3 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) 3HCDH_N PF02737.13 CBZ24367.1 - 0.09 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ilar_coat PF01787.11 CBZ24368.1 - 0.063 12.8 0.2 0.17 11.4 0.1 1.7 1 0 0 1 1 1 0 Ilarvirus coat protein DUF4551 PF15087.1 CBZ24370.1 - 2.6 6.2 4.6 3.8 5.7 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Amidinotransf PF02274.12 CBZ24371.1 - 0.00017 20.8 0.0 0.00026 20.2 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase ADH_zinc_N PF00107.21 CBZ24372.1 - 6.6e-16 58.0 0.0 1.1e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBZ24372.1 - 4e-11 42.6 0.1 5.6e-10 38.9 0.1 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CBZ24372.1 - 4e-08 34.2 0.0 7.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 CBZ24372.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N PF00107.21 CBZ24373.1 - 6.1e-19 67.8 0.0 1.1e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBZ24373.1 - 8.7e-12 46.0 0.1 2.1e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBZ24373.1 - 5.2e-07 29.3 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CAF1A PF12253.3 CBZ24374.1 - 3.9e-08 33.3 1.4 3.9e-08 33.3 1.0 3.2 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 CBZ24374.1 - 0.041 13.2 31.5 0.013 14.8 18.0 2.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 CBZ24374.1 - 0.41 8.3 6.7 0.73 7.4 4.7 1.3 1 0 0 1 1 1 0 Ycf1 ABC1 PF03109.11 CBZ24376.1 - 1.2e-22 80.1 0.0 2.4e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 CBZ24376.1 - 0.078 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain APH PF01636.18 CBZ24376.1 - 0.13 11.9 0.1 0.28 10.8 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Endonuclease_NS PF01223.18 CBZ24377.1 - 5.8e-47 160.0 0.0 1.2e-46 159.0 0.0 1.5 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.1 CBZ24377.1 - 0.11 12.5 0.1 0.37 10.8 0.1 1.8 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease AF-4 PF05110.8 CBZ24379.1 - 5 4.8 24.9 6.7 4.4 17.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.6 CBZ24379.1 - 9.4 4.1 13.8 13 3.7 9.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-CCCH PF00642.19 CBZ24380.1 - 0.0008 19.0 2.5 0.0013 18.3 1.8 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1751 PF08551.5 CBZ24383.1 - 0.00047 20.4 0.8 0.0019 18.4 0.2 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Neuregulin PF02158.10 CBZ24383.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Neuregulin family DUF2201_N PF13203.1 CBZ24383.1 - 0.84 8.7 3.8 1.2 8.1 2.6 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain HEAT PF02985.17 CBZ24385.1 - 2.7e-05 23.8 38.0 0.0025 17.7 0.1 9.5 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 CBZ24385.1 - 0.012 15.8 38.3 0.037 14.3 0.1 8.7 7 2 1 8 8 8 0 HEAT repeats HEAT_EZ PF13513.1 CBZ24385.1 - 9.7 6.8 30.0 0.083 13.4 0.2 7.7 7 0 0 7 7 7 0 HEAT-like repeat RRM_1 PF00076.17 CBZ24386.1 - 3e-39 132.4 0.7 1.7e-15 56.3 0.0 5.4 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ24386.1 - 2.1e-37 126.8 0.0 7.3e-14 51.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ24386.1 - 1.4e-21 76.0 0.1 8.3e-08 31.9 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ24386.1 - 0.049 13.4 0.0 1.3 8.8 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Aa_trans PF01490.13 CBZ24387.1 - 3.6e-06 25.7 1.2 4.3e-06 25.4 0.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bet_v_1 PF00407.14 CBZ24387.1 - 0.12 12.0 0.2 0.25 10.9 0.2 1.5 1 1 0 1 1 1 0 Pathogenesis-related protein Bet v I family Aa_trans PF01490.13 CBZ24388.1 - 1.9e-39 135.3 38.2 4.7e-39 134.0 26.5 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1206 PF06724.6 CBZ24388.1 - 4.7 7.0 13.3 1.1 9.0 0.1 3.7 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1206) dCMP_cyt_deam_1 PF00383.17 CBZ24389.1 - 5.2e-14 51.7 0.0 9.6e-09 34.8 0.0 2.6 1 1 1 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CBZ24389.1 - 0.0018 18.1 1.6 0.3 10.9 0.1 2.3 2 0 0 2 2 2 2 Bd3614-like deaminase MTHFR PF02219.12 CBZ24392.1 - 0.00079 18.6 0.1 0.36 9.8 0.0 3.2 3 0 0 3 3 3 2 Methylenetetrahydrofolate reductase TMEM171 PF15471.1 CBZ24392.1 - 0.38 9.4 3.8 7.4 5.2 2.4 2.4 2 0 0 2 2 2 0 Transmembrane protein family 171 MTHFR PF02219.12 CBZ24393.1 - 0.012 14.7 0.3 10 5.1 0.0 3.5 4 0 0 4 4 4 0 Methylenetetrahydrofolate reductase WD40 PF00400.27 CBZ24394.1 - 5.5e-84 273.3 17.4 1.2e-10 40.8 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 CBZ24394.1 - 3.6e-06 25.3 13.3 0.17 9.9 0.0 5.9 2 1 4 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBZ24394.1 - 0.0031 16.3 0.1 1.9 7.1 0.0 2.7 1 1 2 3 3 3 2 Nup133 N terminal like CEP19 PF14933.1 CBZ24394.1 - 0.024 14.9 0.0 0.037 14.3 0.0 1.3 1 0 0 1 1 1 0 CEP19-like protein BetaGal_dom3 PF13363.1 CBZ24397.1 - 0.034 13.5 0.1 0.1 11.9 0.1 1.8 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 TPR_11 PF13414.1 CBZ24398.1 - 6.6e-06 25.6 0.9 7.5e-05 22.2 0.9 2.5 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 CBZ24398.1 - 4.1e-05 23.1 0.3 1.4 9.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ24398.1 - 0.0064 16.4 4.7 0.032 14.1 2.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ24398.1 - 0.036 13.6 0.4 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2153 PF09921.4 CBZ24398.1 - 0.038 13.5 0.1 0.094 12.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) TPR_9 PF13371.1 CBZ24398.1 - 0.27 11.1 4.1 5 7.0 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ24398.1 - 0.72 10.6 7.2 0.1 13.3 1.8 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Mnd1 PF03962.10 CBZ24398.1 - 7.1 6.2 6.6 0.46 10.1 0.1 2.3 3 0 0 3 3 3 0 Mnd1 family Pkinase PF00069.20 CBZ24399.1 - 1.2e-21 77.0 0.0 1.1e-17 64.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24399.1 - 5.1e-06 25.7 0.0 5.7e-05 22.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase A_deaminase PF00962.17 CBZ24400.1 - 1.2e-08 34.2 1.5 0.00032 19.7 0.1 3.2 3 0 0 3 3 3 3 Adenosine/AMP deaminase NTF2 PF02136.15 CBZ24401.1 - 2.8e-27 95.4 0.7 3e-27 95.3 0.5 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 CBZ24401.1 - 0.00096 19.3 0.0 0.0012 19.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.2 CBZ24401.1 - 0.0011 19.4 0.1 0.0014 19.1 0.1 1.4 1 1 0 1 1 1 1 Putative lumazine-binding SnoaL_2 PF12680.2 CBZ24401.1 - 0.018 15.4 0.1 0.023 15.1 0.1 1.1 1 0 0 1 1 1 0 SnoaL-like domain Nop16 PF09420.5 CBZ24402.1 - 7.5e-27 94.4 5.4 2e-26 93.0 3.7 1.6 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 YpjP PF14005.1 CBZ24402.1 - 0.019 14.7 0.1 0.028 14.1 0.1 1.2 1 0 0 1 1 1 0 YpjP-like protein Glyco_hydro_4C PF11975.3 CBZ24402.1 - 0.024 14.4 0.2 0.033 13.9 0.2 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain DUF3435 PF11917.3 CBZ24402.1 - 0.024 13.3 0.5 0.029 13.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Histone PF00125.19 CBZ24403.1 - 8e-27 93.1 0.6 8e-27 93.1 0.4 2.1 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ24403.1 - 1.3e-05 25.1 0.2 1.3e-05 25.1 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CBZ24403.1 - 2.2e-05 24.5 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 CBZ24403.1 - 0.0098 15.6 0.1 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated RC-P840_PscD PF10657.4 CBZ24404.1 - 0.32 10.8 0.1 2.1 8.1 0.0 2.3 3 0 0 3 3 3 0 Photosystem P840 reaction centre protein PscD Tmemb_cc2 PF10267.4 CBZ24404.1 - 2 6.8 3.9 1.3 7.5 0.2 2.1 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein FKBP_C PF00254.23 CBZ24405.1 - 2.5e-25 88.3 0.0 3.5e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IQ PF00612.22 CBZ24406.1 - 0.055 13.1 64.0 0.13 12.0 1.8 9.9 9 0 0 9 9 9 0 IQ calmodulin-binding motif Ras PF00071.17 CBZ24407.1 - 2.2e-59 199.4 0.1 2.6e-59 199.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ24407.1 - 1.2e-18 67.7 0.0 1.9e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ24407.1 - 7.7e-15 54.5 0.1 9.8e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ24407.1 - 1e-06 28.2 0.1 2.7e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ24407.1 - 6e-06 26.1 0.0 1.1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.1 CBZ24407.1 - 0.00047 19.3 0.1 0.00061 18.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 CBZ24407.1 - 0.0011 18.2 0.3 0.0019 17.4 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CBZ24407.1 - 0.0017 17.5 0.0 0.002 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CBZ24407.1 - 0.0021 18.1 0.0 0.0035 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBZ24407.1 - 0.0024 17.0 0.2 0.0068 15.6 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 CBZ24407.1 - 0.011 15.0 0.0 0.024 13.9 0.0 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Septin PF00735.13 CBZ24407.1 - 0.022 13.8 0.1 0.036 13.0 0.1 1.3 1 0 0 1 1 1 0 Septin AAA_5 PF07728.9 CBZ24407.1 - 0.043 13.5 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Amidase02_C PF12123.3 CBZ24407.1 - 0.077 12.6 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AAA_24 PF13479.1 CBZ24407.1 - 0.084 12.4 0.1 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBZ24407.1 - 0.11 11.9 0.1 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CBZ24407.1 - 0.14 12.4 0.1 0.19 11.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter DUF1119 PF06550.6 CBZ24408.1 - 0.18 10.9 9.8 0.08 12.0 4.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1119) IF-2B PF01008.12 CBZ24413.1 - 5.7e-41 140.3 0.0 4.1e-39 134.2 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family PBP_sp32 PF07222.7 CBZ24414.1 - 0.99 8.5 7.5 0.94 8.6 3.0 2.3 2 0 0 2 2 2 0 Proacrosin binding protein sp32 Histone PF00125.19 CBZ24415.1 - 8e-27 93.1 0.6 8e-27 93.1 0.4 2.1 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ24415.1 - 1.3e-05 25.1 0.2 1.3e-05 25.1 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CBZ24415.1 - 2.2e-05 24.5 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 CBZ24415.1 - 0.0098 15.6 0.1 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 CBZ24417.1 - 8e-27 93.1 0.6 8e-27 93.1 0.4 2.1 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ24417.1 - 1.3e-05 25.1 0.2 1.3e-05 25.1 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CBZ24417.1 - 2.2e-05 24.5 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 CBZ24417.1 - 0.0098 15.6 0.1 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated PNP_UDP_1 PF01048.15 CBZ24419.1 - 1.5e-41 141.8 0.3 1.8e-41 141.6 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Mito_carr PF00153.22 CBZ24420.1 - 1.6e-24 85.3 0.8 2.8e-09 36.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NDUF_B12 PF08122.7 CBZ24420.1 - 0.068 12.9 0.0 8.5 6.1 0.0 2.6 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family RRM_1 PF00076.17 CBZ24421.1 - 2.9e-10 39.6 0.0 6.1e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ24421.1 - 1.1e-09 38.1 0.0 2.6e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ24421.1 - 2.7e-06 27.1 0.8 7.1e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MSP1_C PF07462.6 CBZ24421.1 - 2.1 6.6 11.2 4 5.7 7.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1042 PF06294.6 CBZ24422.1 - 1.3e-14 54.0 0.0 2.4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 CBZ24422.1 - 0.0033 17.0 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain DnaJ PF00226.26 CBZ24423.1 - 4e-08 32.8 0.1 7.4e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1491 PF07372.7 CBZ24424.1 - 0.028 14.3 0.3 0.06 13.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) YABBY PF04690.8 CBZ24424.1 - 0.076 13.2 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 YABBY protein IncA PF04156.9 CBZ24425.1 - 0.00045 19.8 0.6 0.00045 19.8 0.4 5.8 3 1 1 4 4 4 1 IncA protein ELFV_dehydrog_N PF02812.13 CBZ24425.1 - 0.079 12.5 0.0 0.43 10.1 0.0 2.1 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF972 PF06156.8 CBZ24425.1 - 1.6 9.1 22.7 0.48 10.8 3.9 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF972) DUF2458 PF10454.4 CBZ24425.1 - 4.2 7.2 24.7 0.1 12.4 4.8 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF2458) MIF4G PF02854.14 CBZ24426.1 - 7.8e-15 54.8 1.3 3.1e-14 52.8 0.4 2.2 2 0 0 2 2 2 1 MIF4G domain DUF4041 PF13250.1 CBZ24426.1 - 0.013 15.0 0.0 0.043 13.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) Herpes_BLRF2 PF05812.7 CBZ24426.1 - 0.026 14.3 1.0 0.064 13.0 0.7 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TetR_C_8 PF14278.1 CBZ24426.1 - 0.04 14.2 0.5 20 5.6 0.0 3.9 4 0 0 4 4 4 0 Transcriptional regulator C-terminal region Corona_S2 PF01601.11 CBZ24426.1 - 0.39 8.7 2.2 0.29 9.1 0.0 1.8 2 0 0 2 2 2 0 Coronavirus S2 glycoprotein MIG-14_Wnt-bd PF06664.7 CBZ24428.1 - 0.036 12.8 4.2 0.016 14.0 1.1 1.6 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion 7TMR-DISM_7TM PF07695.6 CBZ24428.1 - 0.3 10.7 8.6 0.5 10.0 6.0 1.3 1 0 0 1 1 1 0 7TM diverse intracellular signalling COX15-CtaA PF02628.10 CBZ24428.1 - 0.38 9.5 9.6 0.57 8.9 6.7 1.3 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein ABC2_membrane_2 PF12679.2 CBZ24428.1 - 6.1 5.6 13.7 8.6 5.1 9.5 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein Tetraspannin PF00335.15 CBZ24428.1 - 7.8 5.6 7.5 2 7.6 2.7 1.6 1 1 0 1 1 1 0 Tetraspanin family Ferric_reduct PF01794.14 CBZ24428.1 - 8.6 6.4 9.5 0.95 9.5 2.4 2.0 1 1 0 2 2 2 0 Ferric reductase like transmembrane component LsmAD PF06741.8 CBZ24430.1 - 1.2e-22 79.7 2.2 3.1e-22 78.4 1.5 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 CBZ24430.1 - 1.7e-12 47.1 0.0 4.6e-12 45.6 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain TPR_2 PF07719.12 CBZ24432.1 - 0.041 13.7 1.6 3.3 7.8 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 CBZ24433.1 - 5.6e-16 57.9 9.6 1.1e-15 57.0 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ24433.1 - 1.9e-08 34.1 14.0 3.5e-08 33.3 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ24433.1 - 4.5e-05 23.1 13.1 0.0001 22.0 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 CBZ24433.1 - 0.021 14.3 5.0 0.049 13.1 3.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 CBZ24433.1 - 0.11 12.2 11.8 0.24 11.1 8.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 CBZ24433.1 - 0.54 9.8 9.0 1 8.9 6.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 CBZ24433.1 - 2.4 7.6 9.9 5.6 6.5 6.8 1.6 1 0 0 1 1 1 0 P-11 zinc finger Trichoplein PF13868.1 CBZ24434.1 - 3.4e-68 229.6 153.4 3.4e-68 229.6 106.4 2.0 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin Ras PF00071.17 CBZ24435.1 - 2.3e-54 183.1 0.1 2.9e-54 182.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ24435.1 - 9.7e-17 61.5 0.0 2.9e-16 60.0 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CBZ24435.1 - 4.3e-11 42.3 0.0 5.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ24435.1 - 1.6e-08 34.2 0.0 3.5e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ24435.1 - 3.2e-06 27.0 0.0 4.7e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBZ24435.1 - 1.2e-05 24.5 0.1 1.8e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_18 PF13238.1 CBZ24435.1 - 0.00057 20.2 0.0 0.0013 19.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ24435.1 - 0.00066 19.7 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CBZ24435.1 - 0.0022 17.1 0.0 0.0086 15.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 CBZ24435.1 - 0.0042 16.5 0.0 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 CBZ24435.1 - 0.0089 15.5 0.3 0.76 9.2 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 CBZ24435.1 - 0.015 14.5 0.0 0.023 13.9 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 CBZ24435.1 - 0.022 15.0 0.1 0.085 13.1 0.1 2.0 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 CBZ24435.1 - 0.023 15.4 0.1 0.034 14.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain IIGP PF05049.8 CBZ24435.1 - 0.026 13.3 0.0 0.15 10.8 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.1 CBZ24435.1 - 0.031 13.8 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBZ24435.1 - 0.048 13.8 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Paramyxo_NS_C PF02725.9 CBZ24435.1 - 0.052 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Non-structural protein C AAA_22 PF13401.1 CBZ24435.1 - 0.063 13.4 0.1 0.16 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 CBZ24435.1 - 0.08 11.9 0.1 0.17 10.8 0.0 1.5 2 0 0 2 2 2 0 Septin PRK PF00485.13 CBZ24435.1 - 0.08 12.4 0.2 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 CBZ24435.1 - 0.1 12.1 0.1 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 CBZ24435.1 - 0.11 12.1 0.0 0.38 10.4 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 CBZ24435.1 - 0.13 12.0 0.3 2.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 Ras PF00071.17 CBZ24436.1 - 4.6e-45 152.9 0.0 5.3e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ24436.1 - 2.9e-13 50.3 0.0 4.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ24436.1 - 6.7e-07 28.7 0.0 8.1e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ24436.1 - 7.7e-06 25.2 0.0 8.9e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ24436.1 - 1.9e-05 24.1 0.0 0.00067 19.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ24436.1 - 0.024 14.5 0.0 0.049 13.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase MerC PF03203.9 CBZ24437.1 - 0.026 14.8 1.6 0.049 13.9 1.1 1.5 1 1 0 1 1 1 0 MerC mercury resistance protein AA_permease PF00324.16 CBZ24437.1 - 0.11 10.7 5.0 0.13 10.5 3.5 1.0 1 0 0 1 1 1 0 Amino acid permease DUF4131 PF13567.1 CBZ24437.1 - 0.69 9.2 6.5 5.1 6.4 4.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) WzyE PF06899.6 CBZ24437.1 - 2.9 6.4 8.4 21 3.6 5.9 1.9 1 1 0 1 1 1 0 WzyE protein DUF3099 PF11298.3 CBZ24437.1 - 7.5 6.3 8.1 0.82 9.4 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) RIB43A PF05914.7 CBZ24438.1 - 2.1e-115 385.3 61.6 2.6e-115 385.0 42.7 1.0 1 0 0 1 1 1 1 RIB43A GldM_C PF12080.3 CBZ24438.1 - 0.46 10.4 2.1 0.98 9.3 1.4 1.5 1 0 0 1 1 1 0 GldM C-terminal domain zf-RanBP PF00641.13 CBZ24439.1 - 2.6e-09 36.0 25.1 0.0011 18.0 4.1 3.6 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.2 CBZ24439.1 - 3.7e-07 29.8 19.1 0.0007 19.3 8.1 2.5 1 1 1 2 2 2 2 Double zinc ribbon zf-RING_3 PF14369.1 CBZ24439.1 - 0.11 12.5 0.8 0.11 12.5 0.6 3.5 3 1 0 3 3 3 0 zinc-finger DUF3279 PF11682.3 CBZ24439.1 - 1.3 8.5 17.9 0.42 10.1 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3279) zf-ribbon_3 PF13248.1 CBZ24439.1 - 1.9 7.8 24.4 0.28 10.4 2.7 3.5 3 0 0 3 3 3 0 zinc-ribbon domain Atx10homo_assoc PF09759.4 CBZ24442.1 - 3.6e-30 103.7 0.0 6.5e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain zf-CHY PF05495.7 CBZ24444.1 - 0.051 13.7 0.2 0.099 12.8 0.1 1.4 1 0 0 1 1 1 0 CHY zinc finger Methyltransf_23 PF13489.1 CBZ24445.1 - 6.8e-26 90.9 0.1 9e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ24445.1 - 4.5e-06 27.0 0.1 0.00025 21.4 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ24445.1 - 2e-05 25.0 0.0 0.00083 19.7 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ24445.1 - 0.0041 16.7 0.0 0.023 14.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain c-SKI_SMAD_bind PF08782.5 CBZ24445.1 - 0.058 13.5 0.6 0.18 11.9 0.1 1.9 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Methyltransf_18 PF12847.2 CBZ24445.1 - 0.068 13.7 0.0 0.54 10.8 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain NMD3 PF04981.8 CBZ24445.1 - 0.11 11.6 0.1 0.2 10.7 0.0 1.4 1 1 0 1 1 1 0 NMD3 family Ubie_methyltran PF01209.13 CBZ24445.1 - 0.12 11.4 0.0 0.45 9.5 0.0 1.7 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CBZ24445.1 - 0.16 12.3 0.6 15 5.9 0.1 3.2 2 2 1 3 3 3 0 Methyltransferase domain DUF1861 PF08950.5 CBZ24446.1 - 2.4e-140 466.5 0.4 2.8e-140 466.3 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 CBZ24447.1 - 1.7e-136 453.8 0.2 2e-136 453.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) Phage_hub_GP28 PF11110.3 CBZ24447.1 - 0.089 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Baseplate hub distal subunit DUF1861 PF08950.5 CBZ24448.1 - 2.4e-141 469.8 0.1 2.7e-141 469.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) TylF PF05711.6 CBZ24448.1 - 0.032 13.3 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) DUF1861 PF08950.5 CBZ24449.1 - 3.8e-139 462.5 0.0 4.4e-139 462.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 CBZ24450.1 - 1.4e-139 464.0 0.0 1.6e-139 463.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 CBZ24451.1 - 6.7e-143 474.9 0.0 7.7e-143 474.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.5 CBZ24452.1 - 6.5e-139 461.8 0.1 7.4e-139 461.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) PHO4 PF01384.15 CBZ24453.1 - 2.1e-108 361.8 15.2 3.4e-108 361.1 10.5 1.3 1 1 0 1 1 1 1 Phosphate transporter family BT1 PF03092.11 CBZ24454.1 - 3.3e-149 497.2 11.7 4.1e-149 496.9 8.1 1.0 1 0 0 1 1 1 1 BT1 family FA_desaturase PF00487.19 CBZ24455.1 - 1.3e-27 96.9 26.4 1.3e-27 96.9 18.3 1.9 1 1 1 2 2 2 1 Fatty acid desaturase DUF2530 PF10745.4 CBZ24455.1 - 3.4 7.7 7.1 3.5 7.6 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) ATG16 PF08614.6 CBZ24456.1 - 0.015 15.1 9.2 0.02 14.7 6.2 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 CBZ24456.1 - 0.11 12.3 14.0 0.096 12.5 3.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC155 PF14662.1 CBZ24456.1 - 0.11 12.0 15.2 0.65 9.5 10.6 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 CENP-H PF05837.7 CBZ24456.1 - 0.11 12.6 6.2 0.03 14.5 2.2 1.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) CALCOCO1 PF07888.6 CBZ24456.1 - 0.2 9.9 9.4 0.24 9.6 6.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like GAS PF13851.1 CBZ24456.1 - 0.32 10.1 10.3 0.5 9.5 7.1 1.4 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 CBZ24456.1 - 0.36 10.6 12.7 2.2 8.1 5.0 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding V_ATPase_I PF01496.14 CBZ24456.1 - 1 7.1 6.1 1.2 6.9 4.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HisKA PF00512.20 CBZ24456.1 - 1.4 9.0 5.1 11 6.1 3.6 2.2 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DivIC PF04977.10 CBZ24456.1 - 1.4 8.4 4.5 1.5 8.3 1.0 1.8 1 1 1 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CBZ24456.1 - 1.7 9.0 8.7 4.4 7.6 5.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atrophin-1 PF03154.10 CBZ24456.1 - 3.4 5.6 8.2 4 5.4 5.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family HAUS6_N PF14661.1 CBZ24456.1 - 5.2 6.3 11.4 1.5 8.1 4.2 1.9 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus COPIIcoated_ERV PF07970.7 CBZ24457.1 - 7.1e-54 182.7 0.0 9.9e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CBZ24457.1 - 1.8e-19 69.4 0.0 3.2e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Lant_dehyd_N PF04737.8 CBZ24457.1 - 0.082 12.9 0.1 2.7 8.0 0.1 2.3 2 0 0 2 2 2 0 Lantibiotic dehydratase, N terminus Hexapep PF00132.19 CBZ24458.1 - 1.4e-12 46.5 3.9 5.7e-05 22.4 0.1 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBZ24458.1 - 0.052 13.1 2.2 8.5 6.0 0.1 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase ABC_tran PF00005.22 CBZ24459.1 - 5.5e-28 97.9 0.1 1.1e-27 96.9 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CBZ24459.1 - 9.4e-07 29.0 1.1 0.0013 18.8 0.0 2.1 1 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CBZ24459.1 - 0.00041 19.8 0.8 0.26 10.6 0.3 2.4 2 0 0 2 2 2 2 AAA-like domain SMC_N PF02463.14 CBZ24459.1 - 0.0017 17.6 0.3 0.021 14.0 0.0 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBZ24459.1 - 0.0048 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CBZ24459.1 - 0.0049 16.3 0.2 0.011 15.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CBZ24459.1 - 0.0059 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBZ24459.1 - 0.052 12.9 0.5 0.21 10.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CBZ24459.1 - 0.07 13.2 2.1 0.77 9.8 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CBZ24459.1 - 0.079 13.2 0.1 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CBZ24459.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.8 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 CBZ24459.1 - 0.14 11.7 0.2 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 CBZ24459.1 - 0.2 12.4 1.2 0.51 11.1 0.2 2.1 2 1 0 2 2 2 0 AAA domain SNF2_N PF00176.18 CBZ24460.1 - 4.2e-26 91.4 0.0 6.6e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HNH PF01844.18 CBZ24460.1 - 1.4e-08 34.4 0.3 1.4e-08 34.4 0.2 2.8 2 0 0 2 2 2 1 HNH endonuclease Helicase_C PF00271.26 CBZ24460.1 - 0.00037 20.3 0.0 0.00075 19.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tenui_NS3 PF05310.7 CBZ24460.1 - 0.092 12.6 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Tenuivirus movement protein ResIII PF04851.10 CBZ24460.1 - 0.12 12.2 0.0 1.5 8.6 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit ArgJ PF01960.13 CBZ24460.1 - 0.35 9.2 0.0 0.55 8.5 0.0 1.2 1 0 0 1 1 1 0 ArgJ family Pkinase PF00069.20 CBZ24461.1 - 3.3e-41 141.1 0.0 7.6e-28 97.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24461.1 - 3.7e-17 62.2 0.0 4.7e-10 38.9 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase NCD1 PF04904.8 CBZ24461.1 - 0.018 14.7 0.1 0.043 13.5 0.1 1.6 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) APH PF01636.18 CBZ24461.1 - 0.025 14.3 0.0 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family GRIP PF01465.15 CBZ24462.1 - 1.6e-14 53.1 0.0 3.6e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 GRIP domain Cep57_CLD_2 PF14197.1 CBZ24462.1 - 4.1e-08 33.0 266.5 0.02 14.8 8.2 17.3 10 3 7 18 18 18 11 Centrosome localisation domain of PPC89 Imm42 PF15601.1 CBZ24462.1 - 8.1 5.8 44.3 5.1 6.5 0.7 7.7 7 0 0 7 7 7 0 Immunity protein 42 RRM_1 PF00076.17 CBZ24463.1 - 1e-05 25.0 0.1 4.4e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4636 PF15468.1 CBZ24463.1 - 0.0017 17.8 2.3 0.0023 17.4 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4636) MORN PF02493.15 CBZ24464.1 - 1.5e-22 77.9 29.4 7.6e-07 28.4 0.4 6.4 6 0 0 6 6 6 6 MORN repeat RNase_H PF00075.19 CBZ24464.1 - 0.085 13.2 0.1 0.3 11.4 0.1 1.9 1 0 0 1 1 1 0 RNase H tRNA-synt_2b PF00587.20 CBZ24465.1 - 1.5e-32 112.5 0.0 2.7e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CBZ24465.1 - 2e-14 53.5 4.8 1.1e-13 51.1 0.5 2.3 1 1 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Filo_VP35 PF02097.10 CBZ24465.1 - 0.098 11.8 0.6 0.15 11.2 0.4 1.2 1 0 0 1 1 1 0 Filoviridae VP35 Pkinase PF00069.20 CBZ24466.1 - 5.1e-50 170.0 0.0 6.3e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24466.1 - 1.8e-26 92.7 0.0 2.7e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ24466.1 - 1e-09 37.7 0.0 2e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ24466.1 - 8.9e-05 22.3 0.7 0.00047 19.9 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBZ24466.1 - 0.0023 16.8 0.2 0.0036 16.1 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 CBZ24466.1 - 0.007 15.4 0.1 0.015 14.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBZ24466.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 CBZ24466.1 - 0.024 14.2 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NIF3 PF01784.13 CBZ24468.1 - 1.2e-63 214.8 0.0 1.5e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) PSP1 PF04468.7 CBZ24469.1 - 1.7e-30 104.8 0.1 3e-30 104.0 0.1 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region RAP1 PF07218.6 CBZ24470.1 - 0.18 9.8 9.7 0.25 9.4 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S64 PF08192.6 CBZ24470.1 - 6 5.0 15.5 9.9 4.3 10.7 1.2 1 0 0 1 1 1 0 Peptidase family S64 Period_C PF12114.3 CBZ24470.1 - 6.6 6.2 22.8 17 4.9 15.8 1.7 1 0 0 1 1 1 0 Period protein 2/3C-terminal region 3-PAP PF12578.3 CBZ24472.1 - 2.9e-30 104.9 0.4 1.3e-29 102.8 0.3 2.2 1 0 0 1 1 1 1 Myotubularin-associated protein Dzip-like_N PF13815.1 CBZ24472.1 - 0.0075 16.0 0.0 0.0075 16.0 0.0 3.2 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal PUA PF01472.15 CBZ24473.1 - 2.1e-15 56.1 1.2 3.4e-15 55.5 0.8 1.4 1 0 0 1 1 1 1 PUA domain DUF4160 PF13711.1 CBZ24473.1 - 0.0098 15.7 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4160) FumaraseC_C PF10415.4 CBZ24473.1 - 0.072 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Fumarase C C-terminus FIST PF08495.5 CBZ24473.1 - 0.16 11.0 0.8 0.3 10.2 0.1 1.7 2 0 0 2 2 2 0 FIST N domain RPAP1_N PF08621.5 CBZ24473.1 - 0.59 9.7 3.1 1.4 8.5 0.6 2.1 2 0 0 2 2 2 0 RPAP1-like, N-terminal DEAD PF00270.24 CBZ24474.1 - 2.1e-22 79.3 0.1 3.8e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ24474.1 - 6.8e-09 35.4 0.1 2e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ24474.1 - 2e-05 24.4 0.0 4.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 CBZ24474.1 - 0.061 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Pyrophosphatase PF00719.14 CBZ24476.1 - 5.1e-50 168.9 0.1 8e-50 168.3 0.1 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase EF-hand_7 PF13499.1 CBZ24476.1 - 0.0019 18.3 0.3 0.0091 16.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair Pterin_4a PF01329.14 CBZ24477.1 - 1.4e-30 104.8 0.1 1.6e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Rad51 PF08423.6 CBZ24478.1 - 8.7e-16 57.5 0.0 1.6e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBZ24478.1 - 1.3e-12 47.5 0.6 2.1e-12 46.8 0.4 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CBZ24478.1 - 1.3e-06 27.6 0.0 8.6e-06 25.0 0.0 1.9 2 0 0 2 2 2 1 KaiC DnaB_C PF03796.10 CBZ24478.1 - 3.4e-06 26.1 0.1 0.025 13.4 0.1 2.1 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA PF00004.24 CBZ24478.1 - 4.5e-05 23.6 0.1 0.00019 21.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ24478.1 - 0.00021 21.4 0.0 0.00041 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ24478.1 - 0.0012 18.4 3.5 0.003 17.2 0.2 2.6 1 1 1 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 CBZ24478.1 - 0.0019 18.2 1.5 0.0039 17.1 1.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 CBZ24478.1 - 0.012 15.5 0.5 0.035 13.9 0.3 2.0 1 1 0 1 1 1 0 AAA domain RecA PF00154.16 CBZ24478.1 - 0.013 14.6 0.1 0.026 13.5 0.0 1.5 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_17 PF13207.1 CBZ24478.1 - 0.048 14.4 0.1 0.094 13.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CBZ24478.1 - 0.087 12.5 0.0 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.1 CBZ24478.1 - 0.22 11.8 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.21 CBZ24479.1 - 5.5e-58 195.3 0.1 7.6e-58 194.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ24479.1 - 8.3e-15 53.7 0.2 1.4e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature EF-hand_like PF09279.6 CBZ24479.1 - 0.003 17.5 2.0 0.17 11.9 1.4 2.5 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF365 PF04033.7 CBZ24479.1 - 0.014 15.3 0.6 0.028 14.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Pkinase PF00069.20 CBZ24480.1 - 2.2e-49 167.9 0.0 1.7e-43 148.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24480.1 - 1.3e-28 99.7 0.0 2.7e-23 82.3 0.0 3.3 3 1 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 CBZ24480.1 - 1.1e-07 31.1 0.0 0.00055 18.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CBZ24480.1 - 0.068 12.9 0.1 0.068 12.9 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBZ24480.1 - 0.28 10.4 0.0 0.58 9.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL PEPCK_ATP PF01293.15 CBZ24481.1 - 0.00025 19.6 0.0 0.00037 19.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase FAD_binding_6 PF00970.19 CBZ24482.1 - 2.9e-08 33.7 0.0 7.3e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CBZ24482.1 - 0.0051 17.3 0.0 0.11 13.1 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4551 PF15087.1 CBZ24483.1 - 0.28 9.4 3.3 0.49 8.7 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CCDC74_C PF14917.1 CBZ24484.1 - 0.038 14.0 0.2 0.038 14.0 0.1 3.0 4 0 0 4 4 4 0 Coiled coil protein 74, C terminal SlyX PF04102.7 CBZ24484.1 - 0.24 11.8 2.8 0.31 11.4 0.4 2.3 2 0 0 2 2 2 0 SlyX Sec20 PF03908.8 CBZ24485.1 - 1.4e-08 34.3 2.9 1.4e-08 34.3 2.0 2.0 2 1 0 2 2 2 1 Sec20 Cast PF10174.4 CBZ24485.1 - 0.0019 16.3 6.1 0.0022 16.1 4.2 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF2562 PF10814.3 CBZ24485.1 - 0.019 14.8 1.1 0.019 14.8 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2562) Adeno_PIX PF03955.9 CBZ24485.1 - 8.2 7.0 9.9 0.53 10.8 0.6 2.6 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) PIF1 PF05970.9 CBZ24487.1 - 1.2e-30 106.7 0.8 7.4e-24 84.3 0.6 3.5 3 1 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 CBZ24487.1 - 1.1e-17 64.2 0.0 2.5e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ24487.1 - 0.00022 21.3 0.9 0.0014 18.8 0.3 2.6 2 1 0 2 2 2 1 AAA domain DUF853 PF05872.7 CBZ24487.1 - 0.00036 19.0 1.4 0.00067 18.1 1.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_19 PF13245.1 CBZ24487.1 - 0.00098 18.8 0.9 0.0053 16.4 0.6 2.3 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 CBZ24487.1 - 0.0012 16.7 0.4 0.19 9.4 0.0 2.5 3 0 0 3 3 3 2 Helicase UvrD_C_2 PF13538.1 CBZ24487.1 - 0.023 14.8 0.0 0.11 12.5 0.0 2.2 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain ABC_tran PF00005.22 CBZ24487.1 - 0.18 12.1 0.4 0.54 10.5 0.3 1.8 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.12 CBZ24487.1 - 0.26 11.0 0.2 3 7.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 PIF1 PF05970.9 CBZ24488.1 - 5.9e-36 124.1 0.4 2.5e-28 99.0 0.1 3.4 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 CBZ24488.1 - 1.6e-13 50.6 0.2 2.5e-12 46.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CBZ24488.1 - 2.8e-05 24.2 0.0 9.4e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ24488.1 - 5.8e-05 22.7 3.5 0.00051 19.7 2.4 2.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CBZ24488.1 - 0.0027 17.7 1.7 0.0098 15.8 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 CBZ24488.1 - 0.0036 16.5 0.2 0.01 14.9 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBZ24488.1 - 0.0036 17.0 0.0 0.012 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 CBZ24488.1 - 0.0043 16.6 0.1 4.1 6.8 0.0 2.9 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA PF00004.24 CBZ24488.1 - 0.0046 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Herpes_Helicase PF02689.9 CBZ24488.1 - 0.0069 14.1 0.3 0.038 11.7 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA_11 PF13086.1 CBZ24488.1 - 0.012 15.1 0.1 0.8 9.2 0.0 2.7 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 CBZ24488.1 - 0.013 14.7 0.1 0.04 13.1 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.1 CBZ24488.1 - 0.028 14.5 0.0 0.1 12.7 0.0 2.0 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain NACHT PF05729.7 CBZ24488.1 - 0.1 12.2 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 CBZ24488.1 - 0.15 11.7 0.3 0.34 10.6 0.2 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 CBZ24488.1 - 0.21 11.2 1.2 0.65 9.6 0.1 2.1 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.4 CBZ24488.1 - 0.29 10.0 0.2 0.61 8.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 CBZ24488.1 - 0.29 10.3 0.0 0.48 9.6 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain 14-3-3 PF00244.15 CBZ24490.1 - 5.1e-92 307.2 2.5 6e-92 307.0 1.8 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 CBZ24490.1 - 0.12 12.3 1.6 5 7.1 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat OPA3 PF07047.7 CBZ24491.1 - 1.4e-16 60.4 0.4 1.7e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 Optic atrophy 3 protein (OPA3) Macoilin PF09726.4 CBZ24491.1 - 0.05 11.8 0.4 0.065 11.5 0.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Sporozoite_P67 PF05642.6 CBZ24491.1 - 0.22 9.3 9.5 0.34 8.7 6.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_UL25 PF01499.11 CBZ24491.1 - 0.52 8.5 4.4 0.32 9.2 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family rve_3 PF13683.1 CBZ24492.1 - 1.3 8.6 7.6 0.61 9.6 0.1 3.3 3 0 0 3 3 3 0 Integrase core domain DUF2779 PF11074.3 CBZ24493.1 - 9.4e-44 148.6 0.0 1.9e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) DUF3450 PF11932.3 CBZ24493.1 - 0.19 10.9 10.6 0.5 9.5 7.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Hamartin PF04388.7 CBZ24494.1 - 0.4 9.2 2.2 0.71 8.4 1.5 1.3 1 0 0 1 1 1 0 Hamartin protein TTL PF03133.10 CBZ24495.1 - 7.7e-68 228.5 0.1 1.3e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ24495.1 - 6.6e-07 28.3 0.1 0.00025 19.9 0.0 3.0 2 1 0 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.9 CBZ24495.1 - 0.032 14.0 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain KfrA_N PF11740.3 CBZ24495.1 - 0.18 12.2 1.9 0.42 11.0 0.1 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term BOP1NT PF08145.7 CBZ24496.1 - 7.1e-89 297.9 7.9 1.2e-88 297.2 5.4 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CBZ24496.1 - 9.5e-26 88.7 0.8 1.4e-10 40.6 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CBZ24496.1 - 0.14 11.6 0.0 29 4.2 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CD24 PF14984.1 CBZ24496.1 - 1.5 8.7 15.1 4.2 7.2 10.5 1.7 1 0 0 1 1 1 0 CD24 protein YqzH PF14164.1 CBZ24496.1 - 9 6.2 6.9 7.8 6.4 0.1 3.5 3 1 1 4 4 4 0 YqzH-like protein RCC1 PF00415.13 CBZ24497.1 - 1.3e-19 70.1 19.1 8.1e-05 22.7 0.0 8.8 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ24497.1 - 4.1e-11 42.1 18.9 3.1e-06 26.6 0.3 5.8 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat LRR_4 PF12799.2 CBZ24499.1 - 1.3e-17 62.9 15.5 2.8e-06 26.8 0.1 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24499.1 - 5.7e-12 45.1 19.5 0.00034 20.3 1.4 3.4 3 0 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBZ24499.1 - 2.7e-07 29.7 19.0 1.4 9.2 0.2 6.7 6 1 1 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.1 CBZ24499.1 - 0.00023 20.8 19.0 0.54 10.4 0.1 6.4 6 1 1 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 CBZ24499.1 - 0.0004 20.1 26.4 0.75 10.2 0.1 7.0 7 0 0 7 7 7 3 Leucine rich repeat LRR_9 PF14580.1 CBZ24499.1 - 0.052 13.0 2.8 2.7 7.5 0.1 2.2 1 1 1 2 2 2 0 Leucine-rich repeat Orthopox_F8 PF05886.6 CBZ24499.1 - 0.11 12.3 2.0 0.27 11.0 1.4 1.6 1 0 0 1 1 1 0 Orthopoxvirus F8 protein CorA PF01544.13 CBZ24499.1 - 0.21 10.5 1.2 0.42 9.5 0.8 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DNA_ligase_A_M PF01068.16 CBZ24500.1 - 0.0024 17.2 0.0 2.6 7.3 0.0 3.2 3 0 0 3 3 3 2 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 CBZ24500.1 - 0.019 14.6 0.0 0.074 12.7 0.0 2.0 2 0 0 2 2 2 0 DNA ligase OB-like domain PUF PF00806.14 CBZ24502.1 - 1.7e-09 36.5 0.0 1.9 8.1 0.0 5.8 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat Pox_MCEL PF03291.11 CBZ24504.1 - 1.6e-14 53.5 0.0 2.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_11 PF08241.7 CBZ24504.1 - 4.1e-06 27.2 0.0 0.00015 22.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ24504.1 - 1.3e-05 25.4 0.0 6.7e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ24504.1 - 1.5e-05 24.8 0.0 3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ24504.1 - 1.9e-05 25.0 0.0 6.1e-05 23.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ24504.1 - 0.0001 22.8 0.0 0.00077 20.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain NSP13 PF06460.7 CBZ24504.1 - 0.0033 16.3 0.1 0.0057 15.5 0.0 1.2 1 0 0 1 1 1 1 Coronavirus NSP13 PAM2 PF07145.10 CBZ24504.1 - 0.035 13.6 0.8 0.1 12.1 0.6 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region TPMT PF05724.6 CBZ24504.1 - 0.12 11.8 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 CBZ24504.1 - 0.19 11.3 0.0 0.49 9.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 CBZ24504.1 - 0.21 10.5 0.0 0.45 9.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) MTS PF05175.9 CBZ24504.1 - 0.23 10.8 0.0 0.45 9.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PHF5 PF03660.9 CBZ24504.1 - 0.24 11.4 4.5 0.073 13.1 0.8 1.8 2 0 0 2 2 2 0 PHF5-like protein TPR_11 PF13414.1 CBZ24505.1 - 1.6e-24 85.3 16.6 2e-09 36.9 0.0 5.4 3 1 4 7 7 7 6 TPR repeat TPR_2 PF07719.12 CBZ24505.1 - 1.4e-17 62.1 8.9 9.7e-06 25.1 0.0 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ24505.1 - 4.5e-17 60.8 10.3 0.00012 21.4 0.1 6.4 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ24505.1 - 6.2e-13 49.0 7.7 2.2e-06 28.1 0.1 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ24505.1 - 3e-10 39.8 11.4 0.00056 19.7 0.6 4.2 3 2 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ24505.1 - 1.9e-09 36.9 8.5 0.018 15.1 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ24505.1 - 1.6e-08 33.7 6.3 0.0024 17.5 0.4 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ24505.1 - 6.4e-08 32.5 1.7 0.22 12.0 0.0 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ24505.1 - 9.7e-07 28.8 5.6 0.13 13.0 0.0 5.3 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ24505.1 - 1.4e-06 28.5 9.9 0.78 10.1 0.6 4.6 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ24505.1 - 5.2e-06 25.8 4.8 0.021 14.6 0.0 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ24505.1 - 0.0012 18.9 6.9 0.3 11.2 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Sel1 PF08238.7 CBZ24505.1 - 0.023 15.3 10.2 0.37 11.4 0.2 3.9 4 0 0 4 4 4 0 Sel1 repeat DUF3808 PF10300.4 CBZ24505.1 - 0.028 13.0 0.1 0.12 10.9 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3808) PPTA PF01239.17 CBZ24505.1 - 0.033 13.5 0.1 0.81 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat MIT PF04212.13 CBZ24505.1 - 0.14 12.0 12.9 0.9 9.4 0.2 4.5 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 CBZ24505.1 - 0.35 10.8 6.3 0.75 9.8 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Pkinase PF00069.20 CBZ24507.1 - 7.7e-34 117.0 0.0 1.4e-33 116.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24507.1 - 1.2e-13 50.7 0.0 4.2e-11 42.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBZ24507.1 - 0.0016 17.2 0.1 0.0025 16.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 CBZ24507.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ24507.1 - 0.019 14.3 0.4 0.039 13.2 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.1 CBZ24507.1 - 0.23 10.4 0.0 0.51 9.2 0.0 1.6 2 0 0 2 2 2 0 Kinase-like AA_permease_2 PF13520.1 CBZ24508.1 - 4.7e-20 71.5 39.1 6.5e-20 71.0 27.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBZ24508.1 - 2.8e-06 25.9 35.7 6.7e-06 24.7 24.7 1.6 1 1 0 1 1 1 1 Amino acid permease DUF563 PF04577.9 CBZ24510.1 - 8.5e-12 45.4 0.2 2.9e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Nucleoside_tran PF01733.13 CBZ24511.1 - 2.7e-32 112.1 16.1 3.5e-25 88.7 0.1 2.6 3 0 0 3 3 3 2 Nucleoside transporter Tex_N PF09371.5 CBZ24512.1 - 2.9e-45 153.9 0.2 6.1e-45 152.9 0.1 1.5 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HHH_3 PF12836.2 CBZ24512.1 - 3.7e-10 39.5 0.0 7.1e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 CBZ24512.1 - 7.5e-06 25.5 0.0 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 CBZ24512.1 - 0.00037 20.5 0.0 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.18 CBZ24512.1 - 0.016 15.2 0.0 0.04 14.0 0.0 1.7 1 0 0 1 1 1 0 S1 RNA binding domain Cyt-b5 PF00173.23 CBZ24514.1 - 9e-20 70.2 0.1 1.4e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1653 PF07866.6 CBZ24514.1 - 0.12 12.6 0.4 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1653) Carboxyl_trans PF01039.17 CBZ24515.1 - 1.5e-144 482.0 0.0 1.8e-144 481.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBZ24515.1 - 8.4e-08 31.6 0.0 0.0016 17.7 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) zf-C4H2 PF10146.4 CBZ24516.1 - 0.078 12.9 0.1 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein Peptidase_M17 PF00883.16 CBZ24518.1 - 8.3e-75 251.5 0.1 9.3e-75 251.3 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF3132 PF11330.3 CBZ24518.1 - 0.018 14.8 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) Peptidase_M17 PF00883.16 CBZ24519.1 - 2.8e-83 279.3 0.1 3.9e-83 278.8 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain DUF3132 PF11330.3 CBZ24519.1 - 0.048 13.5 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) MFS_1 PF07690.11 CBZ24521.1 - 1.7e-21 76.3 26.6 1.4e-19 70.0 9.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CBZ24521.1 - 1.3e-08 34.4 11.4 7.6e-08 31.9 7.9 2.3 1 1 0 1 1 1 1 Nodulin-like SPC12 PF06645.8 CBZ24521.1 - 1.2 9.0 0.0 1.2 9.0 0.0 3.6 5 0 0 5 5 5 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MFS_1 PF07690.11 CBZ24522.1 - 2.7e-15 55.9 26.8 7.3e-12 44.6 11.6 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CBZ24522.1 - 2.1e-07 30.4 12.6 2.1e-07 30.4 8.7 2.8 2 2 1 3 3 3 1 Nodulin-like MFS_1 PF07690.11 CBZ24523.1 - 5.3e-14 51.7 40.7 2.6e-11 42.8 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CBZ24523.1 - 7.5e-07 28.6 20.4 7.5e-07 28.6 14.1 3.4 2 2 1 3 3 3 1 Nodulin-like DUF1129 PF06570.6 CBZ24523.1 - 0.26 10.5 12.7 0.68 9.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) COX8 PF02285.10 CBZ24523.1 - 4.1 7.0 6.5 0.62 9.6 0.3 2.8 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIII MFS_1 PF07690.11 CBZ24524.1 - 0.00043 19.1 3.9 0.00047 18.9 2.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_2 PF12796.2 CBZ24525.1 - 2.4e-33 114.3 1.6 7.2e-11 42.2 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ24525.1 - 1.4e-27 94.0 3.7 6.7e-07 28.8 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CBZ24525.1 - 5.1e-23 80.5 6.0 3.5e-08 33.4 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBZ24525.1 - 7.9e-22 77.2 5.5 6.9e-09 35.9 0.0 4.4 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ24525.1 - 5.6e-20 69.4 1.5 0.00015 21.6 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat ArsA_ATPase PF02374.10 CBZ24526.1 - 1.4e-87 293.6 0.1 1.6e-50 171.8 0.0 2.2 2 0 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.18 CBZ24526.1 - 9e-11 41.5 2.3 7.4e-10 38.5 0.8 2.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 CBZ24526.1 - 0.00086 18.7 0.1 0.0025 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.1 CBZ24526.1 - 0.0037 17.2 0.0 0.021 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 CBZ24526.1 - 0.035 13.5 0.2 1.9 7.8 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.17 CBZ24526.1 - 0.05 12.4 0.1 0.093 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Fer4_NifH PF00142.13 CBZ24526.1 - 0.12 11.4 0.0 0.66 9.1 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AIPR PF10592.4 CBZ24527.1 - 2.3 7.4 7.0 1.7 7.8 3.7 1.5 1 1 0 1 1 1 0 AIPR protein Peptidase_C11 PF03415.9 CBZ24528.1 - 4e-06 26.0 0.0 5.9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Clostripain family MIT PF04212.13 CBZ24531.1 - 0.025 14.4 0.8 0.049 13.5 0.5 1.5 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain Ribosomal_S21e PF01249.13 CBZ24532.1 - 2.1e-33 114.1 0.1 2.7e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e Ribosomal_S21e PF01249.13 CBZ24533.1 - 1.9e-33 114.2 0.1 2.4e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e COX6B PF02297.12 CBZ24534.1 - 0.00069 19.5 8.0 0.16 12.0 0.6 2.8 1 1 0 2 2 2 2 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 CBZ24534.1 - 0.19 11.5 8.5 11 6.0 0.2 3.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0203) EF-hand_6 PF13405.1 CBZ24536.1 - 1.1e-13 49.7 0.1 0.076 12.9 0.0 7.0 7 0 0 7 7 7 3 EF-hand domain EF-hand_7 PF13499.1 CBZ24536.1 - 6.8e-11 42.1 0.0 0.15 12.1 0.0 6.0 6 0 0 6 6 6 4 EF-hand domain pair EF-hand_1 PF00036.27 CBZ24536.1 - 3.7e-06 25.8 0.0 1.3 8.5 0.0 5.6 7 1 1 8 8 8 2 EF hand EF-hand_8 PF13833.1 CBZ24536.1 - 0.0084 15.6 0.0 32 4.2 0.0 4.8 5 0 0 5 5 5 1 EF-hand domain pair DUF3552 PF12072.3 CBZ24537.1 - 0.00015 21.0 13.8 0.00021 20.5 9.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) V_ATPase_I PF01496.14 CBZ24537.1 - 1.1 7.0 7.4 1.3 6.7 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DLIC PF05783.6 CBZ24537.1 - 1.7 7.1 6.3 2.4 6.7 4.4 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) APG6 PF04111.7 CBZ24537.1 - 2.2 7.2 14.0 3 6.7 9.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3584 PF12128.3 CBZ24537.1 - 2.5 5.3 20.3 2.9 5.1 14.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4351 PF14261.1 CBZ24538.1 - 0.23 11.3 3.0 12 5.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) TMF_DNA_bd PF12329.3 CBZ24538.1 - 0.31 10.8 24.9 0.016 14.9 10.1 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2203 PF09969.4 CBZ24538.1 - 0.77 9.9 3.1 1.8 8.7 2.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) AAA_13 PF13166.1 CBZ24538.1 - 1 7.7 7.7 1.4 7.2 5.3 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 CBZ24538.1 - 1.6 7.3 11.6 2.8 6.5 8.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Sas10_Utp3 PF04000.10 CBZ24538.1 - 2.1 8.5 6.1 7.2 6.8 4.2 2.0 1 0 0 1 1 1 0 Sas10/Utp3/C1D family DUF342 PF03961.8 CBZ24538.1 - 2.2 6.5 7.3 3.4 5.9 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMCO5 PF14992.1 CBZ24538.1 - 2.4 7.2 8.1 3.7 6.6 5.6 1.2 1 0 0 1 1 1 0 TMCO5 family APG6 PF04111.7 CBZ24538.1 - 8 5.3 12.0 13 4.7 8.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Abhydrolase_6 PF12697.2 CBZ24539.1 - 4.6e-11 43.0 0.2 6.8e-11 42.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ24539.1 - 0.00078 19.2 0.0 0.0012 18.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ24539.1 - 0.027 14.0 0.0 0.15 11.6 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CBZ24540.1 - 2e-12 47.4 0.4 5.1e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ24540.1 - 9.3e-06 25.4 0.0 1.5e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ24540.1 - 0.00037 20.1 0.0 0.075 12.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CBZ24540.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase HEAT PF02985.17 CBZ24541.1 - 0.042 13.9 13.1 4.9 7.5 0.0 6.7 7 0 0 7 7 7 0 HEAT repeat Phage_antitermQ PF06530.7 CBZ24541.1 - 0.047 13.2 0.2 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 Phage antitermination protein Q Kinesin PF00225.18 CBZ24542.1 - 2.7e-86 289.3 0.7 6.3e-85 284.8 0.5 2.5 1 1 0 1 1 1 1 Kinesin motor domain IncA PF04156.9 CBZ24542.1 - 3.8 7.0 17.5 9.3 5.7 4.3 3.4 3 0 0 3 3 3 0 IncA protein START PF01852.14 CBZ24543.1 - 6.5e-21 74.5 0.0 1.4e-20 73.5 0.0 1.5 1 1 0 1 1 1 1 START domain LRR_6 PF13516.1 CBZ24544.1 - 1.1e-24 83.6 11.9 0.11 12.5 0.0 12.3 13 0 0 13 13 13 8 Leucine Rich repeat LRR_4 PF12799.2 CBZ24544.1 - 6.1e-18 64.0 9.5 0.00011 21.7 0.2 8.9 9 2 1 10 10 10 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ24544.1 - 7e-13 46.6 10.0 4 7.8 0.1 11.8 13 0 0 13 13 13 2 Leucine Rich Repeat LRR_8 PF13855.1 CBZ24544.1 - 1.3e-08 34.4 19.8 0.0092 15.7 1.8 7.7 8 3 0 8 8 8 3 Leucine rich repeat LRR_7 PF13504.1 CBZ24544.1 - 9.4e-05 22.0 22.7 9.7 6.9 0.0 10.6 12 0 0 12 12 12 1 Leucine rich repeat Oxidored_nitro PF00148.14 CBZ24544.1 - 0.069 11.7 0.0 1.2 7.6 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Ribosomal_L24e PF01246.15 CBZ24545.1 - 3.7e-30 103.5 1.8 3.7e-30 103.5 1.2 2.5 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.9 CBZ24545.1 - 0.00096 18.7 7.0 0.0016 18.0 4.8 1.3 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif DUF581 PF04570.9 CBZ24545.1 - 0.47 9.7 3.5 1.2 8.4 2.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF581) zf-MYND PF01753.13 CBZ24545.1 - 4.1 7.3 6.6 40 4.1 4.6 2.4 1 1 0 1 1 1 0 MYND finger AAA PF00004.24 CBZ24546.1 - 7.4e-40 136.1 0.0 2.3e-39 134.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ24546.1 - 3.5e-06 27.1 0.0 1.7e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CBZ24546.1 - 1.2e-05 25.2 0.0 2.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CBZ24546.1 - 0.00066 19.5 0.0 0.005 16.7 0.0 2.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ24546.1 - 0.0013 18.7 1.1 0.0013 18.7 0.7 4.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CBZ24546.1 - 0.0018 18.0 0.1 0.013 15.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CBZ24546.1 - 0.0088 15.4 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CBZ24546.1 - 0.0097 16.7 0.1 0.053 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2913 PF11140.3 CBZ24546.1 - 0.021 14.1 0.5 0.049 12.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) AAA_18 PF13238.1 CBZ24546.1 - 0.029 14.6 0.0 0.078 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBZ24546.1 - 0.045 12.9 0.1 0.087 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CBZ24546.1 - 0.066 12.2 0.0 0.16 10.9 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF1792 PF08759.6 CBZ24546.1 - 0.32 10.5 0.1 0.52 9.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) RNA_helicase PF00910.17 CBZ24546.1 - 0.34 11.1 0.0 0.8 9.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 CBZ24546.1 - 0.37 9.6 0.2 0.88 8.3 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PUB PF09409.5 CBZ24547.1 - 3.7e-14 52.2 0.0 7.4e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 PUB domain SHOCT PF09851.4 CBZ24547.1 - 0.00011 21.4 0.5 0.00011 21.4 0.4 2.1 2 0 0 2 2 2 1 Short C-terminal domain DUF1675 PF07897.6 CBZ24547.1 - 1.9 8.2 13.0 0.41 10.4 5.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) DUF1682 PF07946.9 CBZ24547.1 - 2.2 7.0 11.2 3.1 6.5 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Surp PF01805.15 CBZ24548.1 - 0.057 13.0 1.7 0.16 11.6 0.2 2.4 2 0 0 2 2 2 0 Surp module DUF4311 PF14188.1 CBZ24549.1 - 0.52 9.7 0.6 0.87 9.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) SPT6_acidic PF14632.1 CBZ24550.1 - 0.044 13.9 0.1 0.044 13.9 0.1 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_S7 PF00177.16 CBZ24551.1 - 3.5e-38 130.5 0.4 4.1e-38 130.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.16 CBZ24552.1 - 3.5e-38 130.5 0.4 4.1e-38 130.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e zf-HIT PF04438.11 CBZ24553.1 - 9.6e-08 31.5 6.5 1.7e-07 30.7 4.5 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 CBZ24553.1 - 0.014 15.2 4.1 0.025 14.4 2.8 1.4 1 0 0 1 1 1 0 MYND finger zf-FPG_IleRS PF06827.9 CBZ24553.1 - 0.26 10.9 2.8 1.7 8.3 0.1 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Adaptin_N PF01602.15 CBZ24554.1 - 2.4e-83 280.2 0.0 3.2e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CBZ24554.1 - 9.3e-07 29.0 8.9 0.0061 16.8 0.5 5.4 3 2 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 CBZ24554.1 - 0.0028 18.1 14.8 2 9.0 0.2 6.3 6 1 1 7 7 7 2 HEAT-like repeat HEAT PF02985.17 CBZ24554.1 - 0.026 14.5 0.9 17 5.8 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat PEP-utilizers_C PF02896.13 CBZ24555.1 - 3e-101 338.2 0.0 4.7e-101 337.5 0.0 1.3 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.14 CBZ24555.1 - 9.3e-59 199.0 0.0 1.8e-58 198.1 0.0 1.4 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.18 CBZ24555.1 - 2.5e-22 78.2 0.3 6.3e-22 76.9 0.2 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HTH_24 PF13412.1 CBZ24555.1 - 0.0027 17.0 0.1 0.0065 15.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 CBZ24555.1 - 0.006 16.0 0.2 0.018 14.5 0.1 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain Sigma70_r4 PF04545.11 CBZ24555.1 - 0.017 14.4 0.1 0.064 12.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_11 PF08279.7 CBZ24555.1 - 0.053 13.1 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 HTH domain Ovate PF04844.8 CBZ24555.1 - 0.14 11.9 0.1 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Transcriptional repressor, ovate Exo_endo_phos PF03372.18 CBZ24556.1 - 1.6e-05 24.9 0.1 8.9e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Med3 PF11593.3 CBZ24556.1 - 3.8 6.6 7.3 5.8 6.0 4.3 1.8 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Acetone_carb_G PF08882.6 CBZ24558.1 - 0.0062 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Acetone carboxylase gamma subunit RRM_1 PF00076.17 CBZ24559.1 - 0.29 10.7 0.0 19 4.9 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SecY PF00344.15 CBZ24560.1 - 9.9e-87 291.0 9.1 1.2e-86 290.7 6.3 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CBZ24560.1 - 1.9e-16 59.2 0.1 4e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Plug domain of Sec61p TMEM237 PF15383.1 CBZ24560.1 - 0.00085 18.5 0.2 0.0014 17.7 0.2 1.3 1 0 0 1 1 1 1 Transmembrane protein 237 zf-DHHC PF01529.15 CBZ24563.1 - 6.7e-26 90.7 14.5 6.7e-26 90.7 10.0 2.1 1 1 1 2 2 2 1 DHHC palmitoyltransferase Mating_C PF12737.2 CBZ24563.1 - 1.5 7.6 21.9 3.2 6.5 15.2 1.5 1 1 0 1 1 1 0 C-terminal domain of homeodomain 1 zf-DHHC PF01529.15 CBZ24564.1 - 9.5e-22 77.2 18.1 9.5e-22 77.2 12.6 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF3754 PF12576.3 CBZ24564.1 - 2.9 7.5 4.9 14 5.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) p450 PF00067.17 CBZ24565.1 - 2.8e-65 220.6 0.0 3.4e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2267 PF10025.4 CBZ24565.1 - 0.1 12.6 0.1 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) Ribosomal_L28e PF01778.12 CBZ24566.1 - 8.1e-20 71.3 0.5 1.5e-19 70.5 0.1 1.5 1 1 0 1 1 1 1 Ribosomal L28e protein family bPH_6 PF10756.4 CBZ24566.1 - 0.025 14.4 0.9 0.039 13.8 0.7 1.4 1 0 0 1 1 1 0 Bacterial PH domain WD40 PF00400.27 CBZ24567.1 - 3.6e-14 52.0 14.8 8.2e-06 25.5 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Sec16_C PF12931.2 CBZ24567.1 - 1.4e-05 24.9 0.0 3.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 TPR_1 PF00515.23 CBZ24567.1 - 0.036 13.6 0.5 0.92 9.2 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ24567.1 - 0.12 12.0 2.8 0.73 9.5 0.0 2.7 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.12 CBZ24567.1 - 0.63 10.1 7.8 1.5 8.9 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 CBZ24568.1 - 1.5e-43 148.4 0.0 4.3e-43 146.9 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ24568.1 - 9.6e-21 73.8 0.0 9.6e-21 73.8 0.0 2.1 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 CBZ24568.1 - 0.00022 21.1 0.0 0.00054 19.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CBZ24568.1 - 0.00081 19.4 0.4 0.0055 16.8 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 G-alpha PF00503.15 CBZ24568.1 - 0.00093 17.9 0.8 0.00093 17.9 0.6 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.18 CBZ24568.1 - 0.35 10.6 4.2 6.9 6.4 0.0 3.4 3 1 0 3 3 3 0 Dynamin family 60KD_IMP PF02096.15 CBZ24569.1 - 2e-27 96.1 0.1 2.6e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Ribosomal_S8 PF00410.14 CBZ24570.1 - 2e-23 82.6 0.0 2.9e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Solute_trans_a PF03619.11 CBZ24571.1 - 9.6e-84 280.9 19.2 1.2e-83 280.6 13.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Prok-RING_2 PF14445.1 CBZ24571.1 - 0.084 12.8 0.6 0.21 11.5 0.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Skp1 PF01466.14 CBZ24572.1 - 1.2e-33 114.9 2.4 1.8e-33 114.4 1.7 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CBZ24572.1 - 2.3e-11 43.5 0.0 1.4e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 CBZ24572.1 - 0.037 14.0 0.0 0.54 10.2 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain ABC2_membrane_3 PF12698.2 CBZ24573.1 - 1.2e-47 162.5 67.9 3e-35 121.8 18.2 3.0 3 1 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.22 CBZ24573.1 - 1.2e-44 151.9 0.0 1.4e-28 99.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBZ24573.1 - 6e-09 36.2 0.0 0.0053 16.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 CBZ24573.1 - 5.9e-05 22.2 0.1 0.01 15.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ24573.1 - 0.00011 21.6 0.2 0.096 12.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CBZ24573.1 - 0.00017 21.9 4.6 0.038 14.3 0.0 2.6 3 0 0 3 3 2 2 AAA domain SRP54 PF00448.17 CBZ24573.1 - 0.0022 17.4 0.5 0.46 9.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain cobW PF02492.14 CBZ24573.1 - 0.009 15.4 0.2 0.89 8.9 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 CBZ24573.1 - 0.024 14.2 0.2 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 CBZ24573.1 - 0.029 13.7 0.1 4.4 6.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 CBZ24573.1 - 0.032 14.7 0.1 6.8 7.2 0.0 2.8 3 0 0 3 3 2 0 Miro-like protein AAA_15 PF13175.1 CBZ24573.1 - 0.053 12.5 0.0 2.8 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_16 PF13191.1 CBZ24573.1 - 0.054 13.4 0.1 2.1 8.3 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.14 CBZ24573.1 - 0.068 12.3 1.3 11 5.1 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 CBZ24573.1 - 0.097 12.2 0.1 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBZ24573.1 - 0.1 12.5 0.3 17 5.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CBZ24573.1 - 0.11 12.6 0.1 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CBZ24573.1 - 0.12 12.1 0.2 4.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CBZ24573.1 - 0.17 11.5 0.1 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_13 PF13166.1 CBZ24573.1 - 0.18 10.2 0.1 3.6 5.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CBZ24573.1 - 0.19 11.6 0.0 9.4 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CBZ24573.1 - 0.19 10.7 0.0 7.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 CBZ24573.1 - 0.32 10.9 0.2 9.7 6.1 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF3584 PF12128.3 CBZ24573.1 - 6.1 4.0 3.1 19 2.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ABC2_membrane_3 PF12698.2 CBZ24575.1 - 1.1e-52 179.1 36.5 2e-32 112.6 9.5 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 CBZ24575.1 - 4.1e-52 176.1 0.0 9.9e-28 97.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBZ24575.1 - 1.8e-16 60.9 0.0 6.3e-08 32.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 CBZ24575.1 - 2.3e-05 23.7 0.0 0.46 9.6 0.0 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBZ24575.1 - 0.00024 20.5 0.4 0.26 10.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 CBZ24575.1 - 0.00033 20.5 0.0 0.31 10.9 0.0 3.6 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CBZ24575.1 - 0.00034 19.7 0.0 2.5 7.0 0.0 3.6 4 0 0 4 4 4 1 AAA ATPase domain AAA_23 PF13476.1 CBZ24575.1 - 0.00051 20.4 1.7 0.11 12.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 CBZ24575.1 - 0.0011 18.5 0.6 0.24 10.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DUF258 PF03193.11 CBZ24575.1 - 0.004 16.3 0.4 0.052 12.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_2 PF12679.2 CBZ24575.1 - 0.0053 15.6 24.1 0.073 11.9 9.4 2.8 2 0 0 2 2 2 2 ABC-2 family transporter protein UPF0079 PF02367.12 CBZ24575.1 - 0.024 14.2 0.4 5.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 CBZ24575.1 - 0.03 14.4 0.2 5.4 7.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CBZ24575.1 - 0.05 13.1 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CBZ24575.1 - 0.052 12.9 0.1 9 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBZ24575.1 - 0.055 12.9 0.0 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 CBZ24575.1 - 0.059 13.3 0.0 4.5 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 CBZ24575.1 - 0.15 11.4 0.8 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.7 CBZ24575.1 - 0.57 9.2 0.0 8.9 5.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_13 PF13166.1 CBZ24575.1 - 1.9 6.8 0.9 11 4.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CBZ24576.1 - 1.2e-52 177.8 0.0 1.7e-28 99.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CBZ24576.1 - 3.8e-47 161.0 68.3 2.7e-35 122.0 17.8 2.8 3 1 0 3 3 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBZ24576.1 - 1.4e-13 51.4 0.0 0.002 18.1 0.0 4.2 4 0 0 4 4 4 3 AAA domain DUF258 PF03193.11 CBZ24576.1 - 1.8e-05 23.9 0.1 0.013 14.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ24576.1 - 7.7e-05 22.1 0.5 0.12 11.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 CBZ24576.1 - 0.0011 18.8 0.0 1.1 9.2 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 CBZ24576.1 - 0.0028 17.6 0.7 2.6 7.9 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain RCC1_2 PF13540.1 CBZ24576.1 - 0.0029 17.2 0.2 10 5.8 0.0 3.7 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat AAA_25 PF13481.1 CBZ24576.1 - 0.012 15.0 0.1 5.4 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 CBZ24576.1 - 0.013 14.9 0.4 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_15 PF13175.1 CBZ24576.1 - 0.015 14.4 0.0 3.5 6.5 0.0 3.2 4 0 0 4 4 4 0 AAA ATPase domain MobB PF03205.9 CBZ24576.1 - 0.016 14.9 0.2 0.55 9.9 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CBZ24576.1 - 0.02 14.0 0.2 9.7 5.2 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin Miro PF08477.8 CBZ24576.1 - 0.024 15.1 0.0 8.5 6.8 0.0 3.0 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 CBZ24576.1 - 0.033 14.0 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CBZ24576.1 - 0.04 14.7 0.0 1 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CBZ24576.1 - 0.047 13.9 0.0 0.047 13.9 0.0 3.0 4 0 0 4 4 2 0 AAA domain AAA_22 PF13401.1 CBZ24576.1 - 0.06 13.4 0.0 11 6.1 0.0 3.2 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 CBZ24576.1 - 0.062 12.5 0.1 14 4.7 0.0 2.7 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 CBZ24576.1 - 0.073 12.7 0.2 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CBZ24576.1 - 0.073 12.7 0.2 2.4 7.8 0.0 2.8 3 0 0 3 3 2 0 NACHT domain AAA PF00004.24 CBZ24576.1 - 0.083 13.0 0.1 2.1 8.5 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 CBZ24576.1 - 0.094 12.1 4.2 1.1 8.6 0.0 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 CBZ24576.1 - 0.095 12.2 0.0 2.7 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBZ24576.1 - 0.1 12.5 0.4 15 5.5 0.1 2.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CBZ24576.1 - 0.1 11.4 0.1 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.12 CBZ24576.1 - 0.11 12.2 0.2 0.32 10.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 CBZ24576.1 - 0.16 11.8 0.1 12 5.8 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 CBZ24576.1 - 0.19 11.1 0.1 19 4.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain G-alpha PF00503.15 CBZ24576.1 - 0.44 9.1 0.0 7.3 5.1 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_13 PF13166.1 CBZ24576.1 - 2.4 6.5 0.0 4.4 5.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 CBZ24578.1 - 4.9e-59 200.0 65.2 2.5e-42 145.1 13.0 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 CBZ24578.1 - 2.2e-51 173.7 0.0 2e-25 89.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBZ24578.1 - 2.4e-19 70.4 0.0 6.8e-08 32.8 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CBZ24578.1 - 4.3e-06 26.0 0.0 1.6 7.6 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain SMC_N PF02463.14 CBZ24578.1 - 1.5e-05 24.3 0.0 1.1 8.4 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBZ24578.1 - 2.5e-05 24.6 0.4 0.1 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 CBZ24578.1 - 4.4e-05 23.3 0.0 0.087 12.7 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 CBZ24578.1 - 0.00017 21.0 0.6 0.26 10.8 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain SRP54 PF00448.17 CBZ24578.1 - 0.00039 19.9 0.4 0.09 12.2 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DUF258 PF03193.11 CBZ24578.1 - 0.00082 18.5 0.0 0.052 12.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 CBZ24578.1 - 0.0022 17.6 0.7 1.9 8.1 0.0 2.9 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 CBZ24578.1 - 0.012 14.7 0.0 9.1 5.3 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.1 CBZ24578.1 - 0.023 14.0 0.0 8.3 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CBZ24578.1 - 0.029 14.2 0.0 20 5.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 CBZ24578.1 - 0.037 13.6 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 CBZ24578.1 - 0.087 12.0 0.1 4.2 6.5 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 CBZ24578.1 - 0.088 12.2 0.3 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain COX4 PF02936.9 CBZ24578.1 - 0.11 12.1 0.1 0.38 10.4 0.0 1.9 2 0 0 2 2 1 0 Cytochrome c oxidase subunit IV AAA_17 PF13207.1 CBZ24578.1 - 0.12 13.2 0.0 3.4 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CBZ24578.1 - 0.12 12.8 0.0 24 5.4 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 CBZ24578.1 - 0.15 12.0 0.2 8.5 6.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBZ24578.1 - 0.2 11.0 0.0 7 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 CBZ24578.1 - 0.33 10.6 0.7 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_13 PF13166.1 CBZ24578.1 - 0.43 8.9 0.2 11 4.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain TatD_DNase PF01026.16 CBZ24579.1 - 2.1e-44 151.6 0.0 3e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase CBP PF12192.3 CBZ24579.1 - 0.021 14.7 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Fungal calcium binding protein Amidohydro_2 PF04909.9 CBZ24579.1 - 0.021 14.3 0.1 0.11 11.9 0.1 2.2 1 1 0 1 1 1 0 Amidohydrolase ABC2_membrane_3 PF12698.2 CBZ24580.1 - 1.5e-54 185.3 46.1 6.4e-38 130.6 11.6 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 CBZ24580.1 - 1.6e-50 170.9 0.0 1.7e-25 89.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBZ24580.1 - 3.2e-21 76.5 0.0 2.7e-08 34.1 0.0 4.2 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBZ24580.1 - 9.5e-09 34.8 0.0 0.019 14.1 0.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CBZ24580.1 - 4.4e-06 26.0 0.0 1.2 8.1 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain AAA_23 PF13476.1 CBZ24580.1 - 2.1e-05 24.9 0.1 0.11 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBZ24580.1 - 0.00027 20.3 0.3 0.28 10.7 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CBZ24580.1 - 0.00035 19.7 0.0 0.055 12.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRP54 PF00448.17 CBZ24580.1 - 0.001 18.5 1.1 0.26 10.6 0.0 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 CBZ24580.1 - 0.0013 18.5 0.0 2.3 8.1 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 CBZ24580.1 - 0.035 13.1 0.3 9.7 5.2 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.1 CBZ24580.1 - 0.043 13.3 0.0 1.7 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CBZ24580.1 - 0.084 12.3 0.3 4.7 6.6 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 CBZ24580.1 - 0.11 11.7 0.1 4.5 6.4 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family UPF0079 PF02367.12 CBZ24580.1 - 0.12 12.0 0.1 6.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CBZ24580.1 - 0.12 12.2 0.1 22 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBZ24580.1 - 0.12 12.2 0.1 8 6.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CBZ24580.1 - 0.14 12.6 0.0 42 4.6 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_13 PF13166.1 CBZ24580.1 - 0.44 8.9 0.4 11 4.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain GCHY-1 PF02649.9 CBZ24581.1 - 0.031 13.5 0.1 0.06 12.5 0.1 1.5 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 GCOM2 PF15328.1 CBZ24581.1 - 0.13 12.0 2.5 0.17 11.6 1.7 1.4 1 1 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Arm PF00514.18 CBZ24582.1 - 0.00018 21.2 2.1 0.014 15.1 0.0 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 CBZ24582.1 - 0.0026 17.7 6.2 12 6.2 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 CBZ24582.1 - 0.0074 16.5 15.4 0.12 12.7 2.4 4.2 1 1 3 4 4 4 2 HEAT repeats Adaptin_N PF01602.15 CBZ24582.1 - 0.027 12.8 3.1 1.4 7.1 0.0 2.4 2 1 0 2 2 2 0 Adaptin N terminal region Tmemb_170 PF10190.4 CBZ24582.1 - 0.063 13.3 1.6 0.14 12.2 0.8 1.7 1 1 0 1 1 1 0 Putative transmembrane protein 170 Frigida PF07899.6 CBZ24583.1 - 0.007 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Frigida-like protein PapD-like PF14874.1 CBZ24584.1 - 9.3e-46 153.9 0.3 2.1e-45 152.8 0.2 1.6 1 0 0 1 1 1 1 Flagellar-associated PapD-like Nodulin-like PF06813.8 CBZ24585.1 - 9.7e-16 57.7 8.0 9.7e-16 57.7 5.5 2.9 3 0 0 3 3 3 1 Nodulin-like MFS_1 PF07690.11 CBZ24585.1 - 2.3e-10 39.7 46.8 2.5e-07 29.7 29.8 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Wzz PF02706.10 CBZ24585.1 - 1.2 8.9 2.3 2.3 8.0 0.0 2.5 3 0 0 3 3 3 0 Chain length determinant protein CCDC155 PF14662.1 CBZ24586.1 - 0.003 17.1 4.3 0.004 16.7 3.0 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 DUF3450 PF11932.3 CBZ24586.1 - 0.0076 15.5 0.6 0.01 15.1 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) IncA PF04156.9 CBZ24586.1 - 0.023 14.3 0.0 0.027 14.0 0.0 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 CBZ24586.1 - 0.071 12.6 0.6 0.071 12.6 0.4 2.1 1 1 1 2 2 2 0 Septum formation initiator BLOC1_2 PF10046.4 CBZ24586.1 - 0.1 12.7 1.8 0.15 12.1 1.3 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HAUS-augmin3 PF14932.1 CBZ24586.1 - 0.13 11.4 3.1 0.17 11.0 2.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4175 PF13779.1 CBZ24586.1 - 0.14 9.8 4.1 0.17 9.5 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NYD-SP28_assoc PF14775.1 CBZ24586.1 - 0.19 11.4 1.3 7.4 6.3 0.9 2.5 1 1 1 2 2 2 0 Sperm tail C-terminal domain FUSC PF04632.7 CBZ24586.1 - 0.31 9.4 2.1 0.38 9.1 1.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HR1 PF02185.11 CBZ24586.1 - 0.33 10.7 3.9 0.7 9.6 2.4 1.8 2 0 0 2 2 2 0 Hr1 repeat Spc7 PF08317.6 CBZ24586.1 - 0.43 9.1 3.6 0.59 8.7 2.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FliT PF05400.8 CBZ24586.1 - 1.7 9.1 8.1 8.1 6.9 5.6 1.9 1 1 0 1 1 1 0 Flagellar protein FliT DUF904 PF06005.7 CBZ24586.1 - 3.7 7.9 8.4 2.1 8.6 4.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Ribosomal_L4 PF00573.17 CBZ24587.1 - 4.7e-10 39.1 0.0 1.3e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family TruD PF01142.13 CBZ24588.1 - 4.9e-07 28.7 0.0 2.4e-06 26.4 0.0 2.1 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) SH3_9 PF14604.1 CBZ24589.1 - 1.2e-10 40.8 0.0 2.2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBZ24589.1 - 6.5e-09 35.0 0.0 1.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBZ24589.1 - 9e-09 34.6 0.0 1.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF507 PF04368.8 CBZ24589.1 - 0.26 10.9 1.5 0.79 9.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF507) Fzo_mitofusin PF04799.8 CBZ24589.1 - 0.4 10.0 2.4 0.35 10.2 0.1 2.0 2 1 0 2 2 2 0 fzo-like conserved region Siah-Interact_N PF09032.6 CBZ24589.1 - 0.53 10.3 5.5 0.21 11.6 1.5 1.9 2 0 0 2 2 2 0 Siah interacting protein, N terminal IF-2B PF01008.12 CBZ24590.1 - 3.4e-23 82.0 0.7 2.6e-21 75.8 0.5 2.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family ALIX_LYPXL_bnd PF13949.1 CBZ24590.1 - 0.019 13.9 0.1 0.027 13.4 0.1 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV PITH PF06201.8 CBZ24591.1 - 2.1e-32 111.9 0.0 2.6e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain Proteasome PF00227.21 CBZ24592.1 - 3.5e-42 143.8 1.0 4.2e-42 143.5 0.7 1.1 1 0 0 1 1 1 1 Proteasome subunit DAP3 PF10236.4 CBZ24593.1 - 4.2e-28 98.1 0.0 6.5e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.1 CBZ24593.1 - 0.009 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 CBZ24593.1 - 0.039 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 CBZ24593.1 - 0.041 13.5 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Sulfate_tra_GLY PF13792.1 CBZ24594.1 - 0.039 13.6 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif Metallophos PF00149.23 CBZ24595.1 - 0.0085 15.5 0.0 0.021 14.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Isochorismatase PF00857.15 CBZ24596.1 - 2.8e-17 63.1 0.2 4.6e-17 62.4 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family DUF3024 PF11225.3 CBZ24599.1 - 0.04 13.7 1.0 5.7 6.8 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3024) PPR_3 PF13812.1 CBZ24600.1 - 4.3 7.8 5.3 19 5.8 0.0 4.1 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Plus-3 PF03126.13 CBZ24601.1 - 4.9e-12 45.8 0.0 9.9e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_3 PF13920.1 CBZ24601.1 - 1.5e-08 34.1 17.1 2.4e-08 33.5 11.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SelB-wing_1 PF09105.5 CBZ24601.1 - 0.099 12.3 0.4 0.19 11.4 0.3 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix zf-C3HC4_2 PF13923.1 CBZ24601.1 - 0.12 12.3 18.0 0.24 11.4 12.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 CBZ24601.1 - 0.91 9.7 9.2 2.1 8.5 6.4 1.7 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Tropomyosin_1 PF12718.2 CBZ24603.1 - 1.8e-06 27.8 4.8 1.8e-06 27.8 3.3 5.8 3 1 2 5 5 5 2 Tropomyosin like CENP-F_leu_zip PF10473.4 CBZ24603.1 - 0.0072 16.1 3.1 0.0072 16.1 2.1 6.9 3 2 5 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 CBZ24603.1 - 0.22 11.6 42.1 2 8.4 2.0 6.7 1 1 6 8 8 8 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 CBZ24603.1 - 1.6 7.0 32.7 0.029 12.8 6.3 3.5 1 1 3 4 4 4 0 AAA domain Pkinase PF00069.20 CBZ24604.1 - 1e-37 129.6 0.0 9.3e-18 64.3 0.0 3.6 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24604.1 - 1.5e-16 60.2 0.0 1.4e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBZ24604.1 - 0.0084 15.8 0.6 1.3 8.7 0.4 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family LRR_4 PF12799.2 CBZ24606.1 - 1e-12 47.3 1.3 0.00014 21.3 0.1 4.1 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24606.1 - 2.7e-11 43.0 1.0 0.00018 21.2 0.0 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBZ24606.1 - 2.4e-09 35.9 0.8 6.3 7.2 0.0 6.6 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ24606.1 - 6.9e-08 31.4 5.5 8.2 7.1 0.1 6.6 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 CBZ24606.1 - 2.6e-05 23.8 3.9 7.4 6.9 0.0 5.5 4 1 1 5 5 5 3 Leucine Rich repeat Glyco_transf_22 PF03901.12 CBZ24607.1 - 1.6e-52 178.9 28.8 2.5e-41 142.0 13.8 3.1 3 0 0 3 3 3 3 Alg9-like mannosyltransferase family UCH PF00443.24 CBZ24610.1 - 4.7e-25 88.2 0.0 3e-24 85.5 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ24610.1 - 0.00051 19.5 0.0 0.77 9.1 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.24 CBZ24612.1 - 2.6e-45 153.8 0.1 1.1e-44 151.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ24612.1 - 7.8e-09 35.3 0.1 2.8e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ24612.1 - 5.4e-07 29.7 0.2 3.3e-05 23.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CBZ24612.1 - 6.1e-07 29.5 0.2 2.9e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBZ24612.1 - 7e-06 26.2 1.5 0.00019 21.6 0.2 2.7 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 CBZ24612.1 - 7e-05 21.8 0.0 0.00013 20.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CBZ24612.1 - 0.00021 21.2 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ24612.1 - 0.00032 20.3 0.1 0.00073 19.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 CBZ24612.1 - 0.00046 19.8 1.6 0.035 13.7 0.0 3.6 3 1 1 4 4 4 1 NACHT domain RuvB_N PF05496.7 CBZ24612.1 - 0.00057 19.0 0.0 0.0013 17.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBZ24612.1 - 0.00059 20.6 0.0 0.0014 19.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ24612.1 - 0.00065 19.6 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBZ24612.1 - 0.00099 18.5 0.7 0.038 13.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 CBZ24612.1 - 0.0022 17.5 0.0 0.0081 15.7 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 CBZ24612.1 - 0.0025 17.5 0.1 0.0095 15.6 0.0 2.1 2 0 0 2 2 1 1 NTPase AAA_33 PF13671.1 CBZ24612.1 - 0.004 17.0 0.0 0.009 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBZ24612.1 - 0.0049 16.4 0.0 0.012 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ24612.1 - 0.0054 15.8 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 CBZ24612.1 - 0.0063 15.6 0.1 0.018 14.2 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 CBZ24612.1 - 0.0079 15.9 0.6 0.12 12.1 0.0 2.4 2 1 1 3 3 3 1 Archaeal ATPase AAA_24 PF13479.1 CBZ24612.1 - 0.0094 15.5 0.1 0.026 14.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ24612.1 - 0.0096 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CBZ24612.1 - 0.012 14.7 2.9 0.86 8.6 0.0 2.9 3 0 0 3 3 3 0 KaiC TIP49 PF06068.8 CBZ24612.1 - 0.013 14.2 0.0 0.032 12.9 0.0 1.5 1 1 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 CBZ24612.1 - 0.014 14.7 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 CBZ24612.1 - 0.018 14.5 0.1 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 CBZ24612.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein RNA_helicase PF00910.17 CBZ24612.1 - 0.021 15.0 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 CBZ24612.1 - 0.021 14.2 0.1 0.91 8.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 CBZ24612.1 - 0.031 13.1 0.6 0.44 9.3 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain DUF465 PF04325.8 CBZ24612.1 - 0.031 13.9 1.4 0.065 12.9 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) ABC_tran PF00005.22 CBZ24612.1 - 0.041 14.1 0.1 0.17 12.1 0.0 2.3 2 2 0 2 2 2 0 ABC transporter Histone PF00125.19 CBZ24612.1 - 0.058 13.5 0.0 0.24 11.5 0.0 2.1 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 cobW PF02492.14 CBZ24612.1 - 0.064 12.7 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ins_P5_2-kin PF06090.7 CBZ24612.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Robl_LC7 PF03259.12 CBZ24612.1 - 0.066 12.7 0.2 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Roadblock/LC7 domain UPF0079 PF02367.12 CBZ24612.1 - 0.095 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Lactamase_B PF00753.22 CBZ24613.1 - 4.9e-12 45.8 3.0 7.2e-12 45.3 2.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBZ24613.1 - 0.00037 20.1 0.1 0.00055 19.5 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GST_N_2 PF13409.1 CBZ24613.1 - 0.15 12.0 0.0 9 6.3 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain tRNA-synt_1e PF01406.14 CBZ24616.1 - 1.7e-113 378.7 0.0 2.6e-113 378.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CBZ24616.1 - 9.7e-05 21.1 4.4 0.0022 16.7 0.0 3.5 4 0 0 4 4 4 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBZ24616.1 - 0.00027 19.0 0.1 0.015 13.3 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.16 CBZ24616.1 - 0.00085 18.0 1.6 0.012 14.2 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain HA2 PF04408.18 CBZ24617.1 - 6.1e-06 26.1 0.0 1.8e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBZ24617.1 - 7.3e-06 25.7 0.1 1.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ24617.1 - 2.4e-05 23.8 0.0 0.00021 20.8 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-met PF12874.2 CBZ24617.1 - 0.0044 17.1 4.4 0.012 15.7 3.1 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CBZ24617.1 - 0.019 15.1 2.2 0.039 14.1 1.5 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 CBZ24617.1 - 1 9.1 0.2 2 8.1 0.2 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) SET PF00856.23 CBZ24618.1 - 4.1e-06 27.1 3.4 0.011 16.0 0.0 3.2 1 1 1 2 2 2 2 SET domain Orn_Arg_deC_N PF02784.11 CBZ24619.1 - 5.5e-76 255.0 0.0 7.3e-76 254.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CBZ24619.1 - 2.1e-37 127.4 0.0 4.2e-37 126.4 0.0 1.6 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Glycoprotein_G PF00802.14 CBZ24619.1 - 0.16 11.0 0.1 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Pneumovirus attachment glycoprotein G KxDL PF10241.4 CBZ24620.1 - 2e-05 24.4 8.1 2e-05 24.4 5.6 6.4 6 1 1 7 7 7 2 Uncharacterized conserved protein SAC3_GANP PF03399.11 CBZ24621.1 - 1.9e-05 24.3 0.1 0.0021 17.6 0.1 2.3 2 0 0 2 2 2 2 SAC3/GANP/Nin1/mts3/eIF-3 p25 family LrgB PF04172.11 CBZ24622.1 - 0.02 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 LrgB-like family NYD-SP28_assoc PF14775.1 CBZ24622.1 - 0.81 9.4 2.7 3.8 7.2 0.9 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain Myotub-related PF06602.9 CBZ24623.1 - 4.1e-53 180.3 0.0 1.4e-27 96.4 0.1 3.9 3 1 0 3 3 3 2 Myotubularin-like phosphatase domain NOT2_3_5 PF04153.13 CBZ24626.1 - 1.1e-31 109.5 0.3 1.1e-31 109.5 0.2 3.6 3 1 0 3 3 3 1 NOT2 / NOT3 / NOT5 family DUF3499 PF12005.3 CBZ24626.1 - 8.3 6.6 22.0 0.14 12.3 0.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3499) GST_N_3 PF13417.1 CBZ24627.1 - 4.5e-11 42.8 0.0 1e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 CBZ24627.1 - 4.2e-09 36.4 0.0 1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBZ24627.1 - 4.3e-08 33.0 0.0 8.2e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBZ24627.1 - 0.016 15.6 0.1 0.25 11.8 0.0 2.5 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBZ24627.1 - 0.13 12.2 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ETRAMP PF09716.5 CBZ24628.1 - 0.074 13.0 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PUF PF00806.14 CBZ24629.1 - 6.3e-35 116.6 7.3 7.6e-06 25.1 0.1 7.6 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat DapB_N PF01113.15 CBZ24630.1 - 0.0011 18.9 0.1 0.0026 17.6 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus SCP2_2 PF13530.1 CBZ24630.1 - 0.043 13.1 0.0 3.9 6.7 0.0 2.1 2 0 0 2 2 2 0 Sterol carrier protein domain S1-P1_nuclease PF02265.11 CBZ24631.1 - 2.3e-55 187.9 0.0 2.8e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF866 PF05907.8 CBZ24633.1 - 1.5e-25 89.5 0.0 1.8e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Elf1 PF05129.8 CBZ24633.1 - 0.018 14.7 0.2 0.064 12.9 0.0 1.9 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like TK PF00265.13 CBZ24633.1 - 0.053 13.0 0.4 0.15 11.5 0.2 1.7 2 0 0 2 2 2 0 Thymidine kinase Ribosomal_L37ae PF01780.14 CBZ24633.1 - 0.082 12.7 0.7 0.16 11.8 0.1 1.7 1 1 1 2 2 2 0 Ribosomal L37ae protein family DUF581 PF04570.9 CBZ24633.1 - 0.13 11.5 0.1 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF581) Bromodomain PF00439.20 CBZ24635.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 Bromodomain DUF1876 PF08962.6 CBZ24642.1 - 0.0052 16.5 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1876) WW PF00397.21 CBZ24643.1 - 1.9e-07 30.8 0.1 4e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 WW domain ATP-synt_F PF01990.12 CBZ24644.1 - 1e-34 118.7 0.0 1.3e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PGI PF00342.14 CBZ24645.1 - 1.4e-241 802.0 2.5 1.7e-241 801.8 1.7 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.1 CBZ24645.1 - 0.075 13.2 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) OsmC PF02566.14 CBZ24646.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.4 1 1 0 1 1 1 0 OsmC-like protein BssC_TutF PF08201.6 CBZ24647.1 - 0.071 12.5 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 BssC/TutF protein TPR_11 PF13414.1 CBZ24648.1 - 1.4e-05 24.5 18.3 0.0032 17.0 1.8 6.3 6 1 1 7 7 7 2 TPR repeat Fis1_TPR_C PF14853.1 CBZ24648.1 - 0.0061 16.4 0.7 0.044 13.6 0.3 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.12 CBZ24648.1 - 0.0076 16.0 1.5 0.0076 16.0 1.0 8.1 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ24648.1 - 0.0094 16.2 26.4 0.034 14.4 0.9 7.1 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ24648.1 - 0.023 14.3 9.6 2.2 8.0 0.4 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat FUSC_2 PF13515.1 CBZ24649.1 - 1.5e-13 50.8 23.3 1e-11 44.8 6.6 3.3 3 0 0 3 3 3 2 Fusaric acid resistance protein-like Rhabdo_ncap PF00945.13 CBZ24649.1 - 0.011 14.3 0.3 0.02 13.5 0.2 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Activator-TraM PF11657.3 CBZ24649.1 - 0.044 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Transcriptional activator TraM STIL_N PF15253.1 CBZ24649.1 - 0.41 9.2 3.6 0.69 8.5 2.5 1.2 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus FUSC_2 PF13515.1 CBZ24650.1 - 9.1e-09 35.3 4.6 9.1e-09 35.3 3.2 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 CBZ24650.1 - 0.0068 15.1 4.2 0.014 14.1 0.1 2.5 2 0 0 2 2 2 1 Aluminium activated malate transporter Sulfatase PF00884.18 CBZ24651.1 - 3.3e-06 26.5 0.1 2.7e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 CBZ24651.1 - 0.00012 21.5 0.0 0.53 9.5 0.0 2.7 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase TPR_11 PF13414.1 CBZ24652.1 - 7.4e-20 70.3 16.8 1.5e-11 43.7 0.4 5.4 4 1 3 7 7 7 5 TPR repeat TPR_1 PF00515.23 CBZ24652.1 - 4.2e-17 60.9 13.5 5.9e-05 22.5 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ24652.1 - 2.4e-16 58.2 24.4 0.0014 18.3 0.1 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ24652.1 - 2.4e-13 49.4 18.5 7e-05 23.1 0.2 7.0 6 2 2 8 8 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ24652.1 - 7.3e-13 48.8 22.0 0.00028 21.4 0.8 6.0 3 1 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ24652.1 - 3.7e-12 45.0 3.8 0.0049 16.5 0.0 6.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ24652.1 - 4.4e-12 46.1 6.4 4.4e-05 23.7 0.1 5.0 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ24652.1 - 1.4e-07 31.3 29.8 0.0004 20.2 1.1 6.5 3 1 3 7 7 7 4 Tetratricopeptide repeat APC8 PF04049.8 CBZ24652.1 - 2.2e-05 24.2 0.0 9.4e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_15 PF13429.1 CBZ24652.1 - 5.8e-05 22.2 7.3 5.8e-05 22.2 5.1 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ24652.1 - 0.00032 20.2 17.1 0.11 12.3 0.2 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ24652.1 - 0.00046 20.2 18.2 0.018 15.1 0.8 5.9 6 1 1 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBZ24652.1 - 0.0026 17.8 8.4 0.11 12.7 0.2 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ24652.1 - 0.019 14.7 15.0 0.52 10.2 0.1 4.8 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ24652.1 - 0.053 13.4 11.6 0.19 11.6 0.6 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ24652.1 - 0.079 13.4 8.9 0.96 10.0 0.0 5.2 6 1 0 6 6 5 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 CBZ24654.1 - 3.8e-32 111.6 0.0 4.9e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ribonuc_red_lgN PF00317.16 CBZ24654.1 - 0.051 13.3 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain PriCT_2 PF08707.6 CBZ24655.1 - 1.2e-15 57.0 0.2 3.5e-15 55.6 0.1 1.8 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) Trp_syntA PF00290.15 CBZ24655.1 - 0.16 10.5 0.0 0.24 9.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain BTV_NS2 PF04514.7 CBZ24656.1 - 4.2 6.1 12.5 6.3 5.5 8.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2956 PF11169.3 CBZ24656.1 - 8.6 6.3 7.9 19 5.2 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) U79_P34 PF03064.11 CBZ24656.1 - 8.6 5.7 16.9 16 4.9 11.7 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Metallophos PF00149.23 CBZ24657.1 - 8.6e-36 123.2 0.0 1.9e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-TRAF PF02176.13 CBZ24657.1 - 0.00016 22.0 3.1 0.00016 22.0 2.2 3.0 1 1 2 3 3 3 1 TRAF-type zinc finger EF-hand_1 PF00036.27 CBZ24657.1 - 0.00048 19.2 0.0 0.039 13.2 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 CBZ24657.1 - 0.0013 18.2 0.2 0.35 10.5 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.1 CBZ24657.1 - 0.0055 16.8 0.1 0.51 10.5 0.1 3.5 2 1 2 4 4 4 2 EF-hand domain pair zinc_ribbon_2 PF13240.1 CBZ24657.1 - 0.0065 15.9 2.9 0.0065 15.9 2.0 2.5 2 0 0 2 2 2 1 zinc-ribbon domain Metallophos_2 PF12850.2 CBZ24657.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain EF-hand_6 PF13405.1 CBZ24657.1 - 0.02 14.7 0.2 1.5 8.9 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain zf-ribbon_3 PF13248.1 CBZ24657.1 - 0.044 13.0 6.4 2 7.7 0.0 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-tcix PF14952.1 CBZ24657.1 - 1.8 7.9 10.2 32 3.9 1.5 3.8 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding DUF1448 PF07289.6 CBZ24659.1 - 4.6e-147 489.3 0.0 5.3e-147 489.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1448) Vps36_ESCRT-II PF11605.3 CBZ24659.1 - 0.018 14.8 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Voldacs PF03517.8 CBZ24659.1 - 0.034 13.9 0.1 5.1 6.9 0.0 2.5 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling bPH_3 PF14470.1 CBZ24659.1 - 0.15 12.3 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial PH domain Viral_env_E26 PF11050.3 CBZ24660.1 - 0.021 13.9 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 DUF2333 PF10095.4 CBZ24660.1 - 0.066 11.8 0.0 0.072 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) LRR_6 PF13516.1 CBZ24661.1 - 6.8e-20 68.8 7.6 0.088 12.9 0.0 11.3 10 1 1 11 11 11 4 Leucine Rich repeat LRR_4 PF12799.2 CBZ24661.1 - 3.1e-13 48.9 0.2 0.15 11.7 0.0 6.8 6 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ24661.1 - 1.3e-09 36.7 7.0 9.5 6.6 0.0 8.0 8 0 0 8 8 8 3 Leucine Rich Repeat LRR_7 PF13504.1 CBZ24661.1 - 0.0033 17.3 20.9 14 6.4 0.0 8.5 9 0 0 9 9 9 2 Leucine rich repeat LRR_8 PF13855.1 CBZ24661.1 - 0.0083 15.8 11.4 0.24 11.1 0.2 5.8 6 0 0 6 6 6 1 Leucine rich repeat Glyco_hydro_4C PF11975.3 CBZ24661.1 - 1.8 8.2 7.2 3 7.5 5.0 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Sipho_Gp157 PF05565.6 CBZ24661.1 - 7.9 6.0 16.1 0.69 9.4 5.5 2.4 1 1 1 2 2 2 0 Siphovirus Gp157 TPR_MLP1_2 PF07926.7 CBZ24661.1 - 8.1 6.1 27.6 0.55 9.9 15.2 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF962 PF06127.6 CBZ24662.1 - 3.9e-24 84.3 0.2 4.4e-24 84.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Gly-zipper_OmpA PF13436.1 CBZ24662.1 - 0.037 13.6 0.1 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 CBZ24662.1 - 0.066 12.7 6.5 0.095 12.2 4.5 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper UCR_Fe-S_N PF10399.4 CBZ24662.1 - 1.1 8.4 7.7 0.4 9.8 0.3 2.3 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal LRR_4 PF12799.2 CBZ24663.1 - 4.9e-25 86.6 1.3 6.2e-05 22.5 0.0 7.4 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24663.1 - 5.7e-19 67.6 3.1 0.0021 17.7 0.0 5.4 5 0 0 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 CBZ24663.1 - 1.6e-11 42.5 0.0 2.6 8.4 0.0 9.0 11 0 0 11 11 11 2 Leucine Rich Repeat LRRNT_2 PF08263.7 CBZ24663.1 - 0.012 15.5 0.6 0.054 13.4 0.4 2.2 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 CBZ24663.1 - 0.078 13.0 6.3 36 4.8 0.0 6.1 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.2 CBZ24664.1 - 2.4e-07 30.2 0.1 0.0004 19.9 0.2 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24664.1 - 5.7e-06 25.9 0.0 8.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CBZ24664.1 - 1.6e-05 24.2 0.0 0.76 10.0 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich Repeat Retinal PF15449.1 CBZ24664.1 - 0.85 7.1 24.7 1 6.9 17.1 1.0 1 0 0 1 1 1 0 Retinal protein TFIIA PF03153.8 CBZ24664.1 - 1.4 8.7 13.7 1.8 8.4 9.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 CBZ24664.1 - 5.2 6.3 23.0 6.8 5.9 16.0 1.1 1 0 0 1 1 1 0 Vta1 like SOG2 PF10428.4 CBZ24664.1 - 5.6 5.4 25.1 7 5.1 17.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein LRR_4 PF12799.2 CBZ24665.1 - 4.2e-10 39.0 0.0 0.0045 16.5 0.0 3.2 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24665.1 - 1.6e-06 27.7 0.1 0.01 15.6 0.0 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBZ24665.1 - 5.5e-05 22.6 0.0 0.59 10.3 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich Repeat cEGF PF12662.2 CBZ24665.1 - 0.052 13.1 0.9 0.13 11.8 0.6 1.7 1 0 0 1 1 1 0 Complement Clr-like EGF-like RTX PF02382.10 CBZ24665.1 - 0.69 8.1 2.9 2.9 6.0 0.9 1.9 2 0 0 2 2 2 0 RTX N-terminal domain LRR_4 PF12799.2 CBZ24666.1 - 2.2e-07 30.3 0.1 0.017 14.7 0.0 3.3 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24666.1 - 8.8e-06 25.3 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBZ24666.1 - 0.00085 19.0 0.0 0.97 9.7 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich Repeat LRRNT_2 PF08263.7 CBZ24666.1 - 0.0081 16.1 1.0 0.021 14.7 0.1 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.2 CBZ24667.1 - 3.8e-10 39.1 0.1 0.01 15.4 0.1 4.1 1 1 4 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24667.1 - 2.7e-07 30.2 0.0 0.023 14.4 0.0 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBZ24667.1 - 0.00048 19.7 0.0 1.2 9.4 0.0 4.8 5 0 0 5 5 5 1 Leucine Rich Repeat LRRNT_2 PF08263.7 CBZ24667.1 - 0.012 15.5 1.1 0.026 14.5 0.1 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_4 PF12799.2 CBZ24668.1 - 4.3e-25 86.8 1.3 6e-05 22.5 0.0 7.4 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24668.1 - 5.2e-19 67.7 3.1 0.002 17.8 0.0 5.4 5 0 0 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 CBZ24668.1 - 1.4e-11 42.7 0.0 2.5 8.4 0.0 9.0 11 0 0 11 11 11 2 Leucine Rich Repeat LRRNT_2 PF08263.7 CBZ24668.1 - 0.012 15.5 0.6 0.054 13.4 0.4 2.2 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 CBZ24668.1 - 0.071 13.2 6.3 35 4.8 0.0 6.2 8 0 0 8 8 8 0 Leucine Rich repeat LRR_4 PF12799.2 CBZ24669.1 - 2.9e-28 96.9 13.2 0.00045 19.7 0.0 8.6 3 1 6 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24669.1 - 1.5e-22 79.1 11.5 4e-06 26.4 0.6 6.6 1 1 6 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 CBZ24669.1 - 2.2e-16 57.3 0.6 1.2 9.4 0.0 10.9 12 0 0 12 12 12 4 Leucine Rich Repeat LRRNT_2 PF08263.7 CBZ24669.1 - 0.0029 17.5 0.3 0.0029 17.5 0.2 2.8 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.1 CBZ24669.1 - 0.6 10.3 19.3 3.7 7.9 0.0 8.0 9 0 0 9 9 9 0 Leucine Rich repeat HJURP_C PF12347.3 CBZ24669.1 - 4.1 7.0 5.3 64 3.2 0.0 4.8 6 0 0 6 6 6 0 Holliday junction regulator protein family C-terminal repeat LRR_4 PF12799.2 CBZ24671.1 - 6e-08 32.1 0.0 0.017 14.7 0.0 3.5 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24671.1 - 1.3e-05 24.8 0.0 0.021 14.5 0.0 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBZ24671.1 - 0.0022 17.7 0.0 1.1 9.5 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich Repeat LRRNT_2 PF08263.7 CBZ24671.1 - 0.0068 16.3 1.1 0.015 15.2 0.1 2.2 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain RTX PF02382.10 CBZ24671.1 - 0.54 8.4 2.8 4.4 5.4 0.7 2.1 2 0 0 2 2 2 0 RTX N-terminal domain LRR_4 PF12799.2 CBZ24672.1 - 1.5e-09 37.2 0.1 0.013 15.1 0.1 4.1 1 1 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24672.1 - 2.5e-07 30.3 0.0 0.018 14.8 0.0 2.6 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBZ24672.1 - 0.0027 17.5 0.0 4.2 7.7 0.0 4.6 5 0 0 5 5 5 1 Leucine Rich Repeat LRRNT_2 PF08263.7 CBZ24672.1 - 0.014 15.3 1.1 0.028 14.3 0.1 2.2 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Mucin PF01456.12 CBZ24672.1 - 0.58 9.9 30.9 0.064 13.0 16.9 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein LRR_7 PF13504.1 CBZ24672.1 - 2.3 8.7 5.4 12 6.5 0.0 4.5 5 0 0 5 5 5 0 Leucine rich repeat DnaJ PF00226.26 CBZ24675.1 - 4.2e-13 48.8 0.0 7.8e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain zf-C3HC4_3 PF13920.1 CBZ24675.1 - 0.11 12.2 10.5 0.21 11.2 7.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PDZ_2 PF13180.1 CBZ24676.1 - 0.0088 15.9 0.0 0.034 14.0 0.0 2.0 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBZ24676.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Oxidored_FMN PF00724.15 CBZ24677.1 - 3.9e-81 272.6 0.0 9e-81 271.5 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.16 CBZ24677.1 - 0.028 13.6 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Oxidored_FMN PF00724.15 CBZ24678.1 - 1.9e-141 471.0 0.0 1.5e-77 260.8 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family DUF2404 PF10296.4 CBZ24680.1 - 1.2e-19 70.2 0.0 2.2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF2404 PF10296.4 CBZ24681.1 - 3.7e-23 81.4 0.0 7.8e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) CSD PF00313.17 CBZ24682.1 - 0.00025 20.7 0.0 0.01 15.6 0.0 2.5 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain ABC_tran PF00005.22 CBZ24683.1 - 1.2e-11 45.0 0.0 4.1e-10 40.1 0.0 2.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ24683.1 - 3e-05 24.1 0.0 0.051 13.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ24683.1 - 0.0024 17.9 0.4 0.0074 16.2 0.3 1.8 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CBZ24683.1 - 0.007 15.5 0.1 0.014 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ24683.1 - 0.048 13.1 0.2 0.048 13.1 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CBZ24683.1 - 0.1 12.0 0.2 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 CBZ24683.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ24683.1 - 0.18 11.9 0.0 1 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 CBZ24683.1 - 0.3 10.4 0.1 0.71 9.2 0.0 1.6 2 0 0 2 2 2 0 Guanylate kinase AAA_17 PF13207.1 CBZ24683.1 - 0.61 10.9 1.7 2 9.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 CBZ24683.1 - 1.3 7.9 0.0 13 4.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SlyX PF04102.7 CBZ24685.1 - 0.058 13.7 0.4 0.18 12.1 0.3 1.8 1 0 0 1 1 1 0 SlyX DUF3639 PF12341.3 CBZ24686.1 - 2.1e-08 33.9 0.2 7.7e-08 32.1 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) WD40 PF00400.27 CBZ24686.1 - 1.2e-05 25.0 0.4 0.17 11.8 0.0 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF2121 PF09894.4 CBZ24686.1 - 0.25 10.6 0.0 0.52 9.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) SNARE_assoc PF09335.6 CBZ24687.1 - 3.4e-20 72.4 5.9 3.4e-20 72.4 4.1 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4117 PF13491.1 CBZ24687.1 - 8.3 5.8 11.1 2.4 7.5 3.8 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4117) zf-C3HC4_2 PF13923.1 CBZ24688.1 - 2.6e-08 33.7 8.4 1.1e-07 31.7 4.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ24688.1 - 1.3e-05 24.6 3.8 1.3e-05 24.6 2.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ24688.1 - 0.00079 19.1 7.9 0.00079 19.1 5.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ24688.1 - 0.0015 18.3 4.6 0.0015 18.3 3.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBZ24688.1 - 0.002 17.7 3.2 0.0047 16.6 2.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 CBZ24688.1 - 0.0037 17.0 10.2 0.0037 17.0 7.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 CBZ24688.1 - 0.66 9.7 11.7 0.28 10.9 5.8 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Peptidase_M1 PF01433.15 CBZ24689.1 - 4.1e-71 240.1 0.0 3.8e-51 174.3 0.0 2.9 2 1 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBZ24689.1 - 2.7e-11 43.6 0.0 5.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily zf-RanBP PF00641.13 CBZ24690.1 - 0.15 11.2 2.4 0.29 10.2 1.6 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Methyltransf_31 PF13847.1 CBZ24691.1 - 6.4e-14 51.7 0.0 8.8e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ24691.1 - 3.3e-12 46.9 0.1 5.7e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBZ24691.1 - 1.3e-11 44.1 0.0 2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 CBZ24691.1 - 8e-11 41.5 0.0 1e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_26 PF13659.1 CBZ24691.1 - 3.9e-09 36.5 0.0 1e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ24691.1 - 3e-08 34.0 0.0 6.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ24691.1 - 3.3e-08 33.3 0.1 8.5e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBZ24691.1 - 1e-07 31.5 0.2 1.6e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CBZ24691.1 - 5.3e-07 29.9 0.1 1.4e-06 28.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ24691.1 - 2.4e-06 27.9 0.0 5.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CBZ24691.1 - 8.3e-06 24.7 0.1 1.2e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 CBZ24691.1 - 3.3e-05 23.1 0.6 7.5e-05 21.9 0.4 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 CBZ24691.1 - 7.7e-05 21.8 0.1 0.00012 21.2 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 CBZ24691.1 - 0.003 17.5 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 CBZ24691.1 - 0.0061 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CBZ24691.1 - 0.0066 16.0 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_4 PF02390.12 CBZ24691.1 - 0.01 14.9 0.0 0.019 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 CBZ24691.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 CBZ24691.1 - 0.048 13.0 0.1 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) SET PF00856.23 CBZ24694.1 - 8.7e-09 35.8 0.8 3.1e-08 34.0 0.2 2.1 3 0 0 3 3 3 1 SET domain zf-MYND PF01753.13 CBZ24694.1 - 0.0097 15.7 12.6 0.0097 15.7 8.7 2.7 2 1 0 2 2 2 1 MYND finger TPR_2 PF07719.12 CBZ24694.1 - 0.032 14.1 1.0 0.24 11.3 0.6 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ24694.1 - 0.1 12.2 1.7 0.21 11.2 0.2 2.3 2 0 0 2 2 2 0 TPR repeat FAM91_C PF14648.1 CBZ24695.1 - 3.6e-160 533.6 0.1 4.5e-160 533.3 0.0 1.1 1 0 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.1 CBZ24695.1 - 2.4e-113 378.2 0.2 3.3e-113 377.8 0.1 1.1 1 0 0 1 1 1 1 FAM91 N-terminus Vps39_2 PF10367.4 CBZ24696.1 - 5.9e-26 90.7 0.2 1.3e-25 89.6 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 CBZ24696.1 - 1.4e-08 34.7 0.1 1.2e-07 31.6 0.0 2.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 CBZ24696.1 - 5.1e-05 22.8 0.0 9.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 CBZ24696.1 - 0.00022 20.8 0.0 0.0021 17.6 0.0 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS Rad50_zn_hook PF04423.9 CBZ24696.1 - 0.12 11.8 0.1 0.33 10.4 0.1 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif Abhydrolase_5 PF12695.2 CBZ24697.1 - 4.4e-11 42.7 0.0 9.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ24697.1 - 3.8e-05 23.6 0.2 0.0011 18.9 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ24697.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family MAP65_ASE1 PF03999.7 CBZ24698.1 - 2.2 6.7 11.0 3.2 6.2 7.6 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) WD40 PF00400.27 CBZ24699.1 - 1.4e-09 37.4 3.7 0.45 10.4 0.6 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat LisH PF08513.6 CBZ24699.1 - 0.16 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 LisH Prenyltransf PF01255.14 CBZ24700.1 - 7.8e-53 178.8 1.2 2.5e-50 170.7 0.1 2.2 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Maf1 PF09174.5 CBZ24700.1 - 0.0003 20.6 0.0 0.00065 19.5 0.0 1.5 2 0 0 2 2 2 1 Maf1 regulator IL13 PF03487.8 CBZ24700.1 - 0.082 12.6 0.3 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Interleukin-13 BicD PF09730.4 CBZ24701.1 - 0.0041 15.5 0.3 0.0051 15.2 0.2 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Laminin_I PF06008.9 CBZ24701.1 - 0.05 12.9 0.6 0.067 12.5 0.4 1.2 1 0 0 1 1 1 0 Laminin Domain I DUF3086 PF11285.3 CBZ24701.1 - 0.054 12.3 0.3 0.07 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) PilJ PF13675.1 CBZ24701.1 - 0.084 13.1 0.5 0.21 11.9 0.2 1.6 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term GTPase_Cys_C PF12631.2 CBZ24701.1 - 0.11 12.8 0.3 0.33 11.3 0.1 1.8 1 1 1 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Toxin_52 PF15605.1 CBZ24702.1 - 0.017 15.0 0.1 0.27 11.1 0.0 2.7 2 1 1 3 3 3 0 Putative toxin 52 ACR_tran PF00873.14 CBZ24702.1 - 0.13 9.6 0.1 0.16 9.3 0.1 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF3847 PF12958.2 CBZ24702.1 - 6.6 6.5 10.7 12 5.7 3.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) RNase_HII PF01351.13 CBZ24703.1 - 2.4e-19 69.7 0.1 6.4e-17 61.8 0.1 2.3 1 1 0 1 1 1 1 Ribonuclease HII YopJ PF03421.11 CBZ24704.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase DNA_pol_A PF00476.15 CBZ24706.1 - 8.9e-28 96.9 0.0 2.9e-27 95.3 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase family A RNase_T PF00929.19 CBZ24706.1 - 6.3e-16 59.0 0.0 2e-15 57.4 0.0 2.0 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.1 CBZ24706.1 - 0.019 14.7 0.0 0.098 12.4 0.0 2.2 2 0 0 2 2 2 0 RNase_H superfamily Peptidase_M32 PF02074.10 CBZ24707.1 - 3.2e-126 421.8 0.0 3.5e-126 421.7 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase SURF1 PF02104.10 CBZ24709.1 - 1.7e-27 96.6 0.0 4.2e-27 95.3 0.0 1.6 1 1 0 1 1 1 1 SURF1 family DUF1471 PF07338.8 CBZ24709.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) F_actin_bind PF08919.5 CBZ24710.1 - 0.0012 18.5 0.5 0.002 17.8 0.3 1.6 1 1 0 1 1 1 1 F-actin binding Atg14 PF10186.4 CBZ24710.1 - 0.011 14.7 5.1 0.015 14.2 3.6 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Myosin_tail_1 PF01576.14 CBZ24710.1 - 0.015 13.0 7.3 0.015 13.0 5.1 1.0 1 0 0 1 1 1 0 Myosin tail Exc PF07825.6 CBZ24710.1 - 0.024 14.3 0.1 0.088 12.5 0.0 1.8 2 0 0 2 2 2 0 Excisionase-like protein Zwint PF15556.1 CBZ24710.1 - 0.029 13.6 4.6 0.032 13.4 3.2 1.0 1 0 0 1 1 1 0 ZW10 interactor DUF2075 PF09848.4 CBZ24710.1 - 0.032 13.2 1.3 0.037 13.0 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CRF PF00473.12 CBZ24710.1 - 0.05 13.6 4.0 0.18 11.9 2.8 2.0 1 0 0 1 1 1 0 Corticotropin-releasing factor family TSKS PF15358.1 CBZ24710.1 - 0.06 11.5 2.5 0.066 11.3 1.7 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate ResIII PF04851.10 CBZ24710.1 - 0.07 12.9 0.6 0.087 12.6 0.4 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Troponin PF00992.15 CBZ24710.1 - 0.13 12.3 5.7 0.16 12.0 4.0 1.2 1 0 0 1 1 1 0 Troponin DUF972 PF06156.8 CBZ24710.1 - 0.14 12.5 5.4 1.7 9.0 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3166 PF11365.3 CBZ24710.1 - 0.14 12.5 7.0 0.24 11.8 4.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3166) Spc24 PF08286.6 CBZ24710.1 - 0.28 10.8 2.3 0.33 10.6 1.6 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4472 PF14739.1 CBZ24710.1 - 0.54 10.7 7.1 0.54 10.7 4.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) Jnk-SapK_ap_N PF09744.4 CBZ24710.1 - 0.9 9.5 9.5 0.49 10.3 1.2 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 IncA PF04156.9 CBZ24710.1 - 1.2 8.6 7.8 1.3 8.5 5.4 1.1 1 0 0 1 1 1 0 IncA protein TSC22 PF01166.13 CBZ24710.1 - 1.6 8.7 7.8 1.1 9.2 3.0 2.2 1 1 0 2 2 2 0 TSC-22/dip/bun family Kinesin PF00225.18 CBZ24711.1 - 1.1e-88 297.2 0.0 1.5e-88 296.7 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain zf-TRAF PF02176.13 CBZ24711.1 - 3.8e-18 65.5 40.1 3.8e-07 30.3 5.6 5.2 5 0 0 5 5 5 4 TRAF-type zinc finger zf-Di19 PF05605.7 CBZ24711.1 - 0.0089 16.1 22.4 0.018 15.1 0.4 4.5 3 1 2 5 5 5 4 Drought induced 19 protein (Di19), zinc-binding Herpes_UL35 PF04496.7 CBZ24712.1 - 0.027 14.6 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL35 family cNMP_binding PF00027.24 CBZ24714.1 - 2.3e-33 113.8 0.4 2.4e-19 68.9 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 CBZ24714.1 - 0.011 15.7 1.9 4.5 7.6 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich repeat COX17 PF05051.8 CBZ24714.1 - 0.055 13.5 0.1 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) W2 PF02020.13 CBZ24714.1 - 0.1 12.5 0.1 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon MOZ_SAS PF01853.13 CBZ24715.1 - 4.8e-22 78.1 0.0 2.3e-12 46.5 0.0 2.3 2 0 0 2 2 2 2 MOZ/SAS family TPR_12 PF13424.1 CBZ24716.1 - 5.1e-14 51.9 15.4 2.7e-06 27.2 0.1 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ24716.1 - 6.9e-07 29.0 15.9 0.05 13.5 0.2 6.0 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ24716.1 - 1.7e-05 24.3 10.1 0.24 11.3 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ24716.1 - 0.0069 15.9 1.4 3.2 7.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ24716.1 - 0.022 15.4 19.7 1.3 9.7 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ24716.1 - 0.026 14.1 4.5 2.1 8.0 0.1 4.3 6 0 0 6 6 6 0 TPR repeat TPR_8 PF13181.1 CBZ24716.1 - 0.13 12.1 0.6 37 4.4 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ24716.1 - 0.36 11.3 9.2 30 5.3 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ24716.1 - 0.51 10.5 2.6 7.3 6.8 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CBZ24716.1 - 0.93 9.4 10.4 1.9 8.5 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat Reprolysin_3 PF13582.1 CBZ24717.1 - 0.0087 16.5 0.1 0.016 15.7 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Lipase_3 PF01764.20 CBZ24718.1 - 1.8e-14 53.5 0.0 3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CBZ24718.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.7 CBZ24718.1 - 0.19 11.4 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) FYVE PF01363.16 CBZ24718.1 - 8.2 6.4 28.9 0.28 11.0 15.1 2.3 2 1 0 2 2 2 0 FYVE zinc finger Lipase_3 PF01764.20 CBZ24719.1 - 2.5e-15 56.3 0.0 4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Ras PF00071.17 CBZ24720.1 - 4.8e-53 178.8 0.3 5.8e-53 178.6 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ24720.1 - 2.4e-17 63.5 0.0 3.4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ24720.1 - 2.1e-13 49.8 0.0 2.7e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ24720.1 - 1.3e-09 37.5 0.1 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ24720.1 - 2.3e-06 27.5 0.0 3.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBZ24720.1 - 0.00022 21.3 0.0 0.00035 20.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBZ24720.1 - 0.00027 20.1 0.4 0.00062 18.9 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBZ24720.1 - 0.00035 20.6 0.0 0.0005 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 CBZ24720.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.9 CBZ24720.1 - 0.004 16.8 0.0 0.0072 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) G-alpha PF00503.15 CBZ24720.1 - 0.0042 15.8 0.5 0.054 12.1 0.1 2.1 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 CBZ24720.1 - 0.0056 16.1 0.0 0.038 13.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBZ24720.1 - 0.0085 15.3 0.0 0.072 12.3 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B PRK PF00485.13 CBZ24720.1 - 0.01 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SRPRB PF09439.5 CBZ24720.1 - 0.016 14.3 0.0 0.021 14.0 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.17 CBZ24720.1 - 0.02 15.0 0.1 0.034 14.3 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_32 PF13654.1 CBZ24720.1 - 0.034 12.8 0.2 0.1 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 CBZ24720.1 - 0.036 14.0 0.0 0.083 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 CBZ24720.1 - 0.037 14.3 0.0 0.049 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 CBZ24720.1 - 0.037 12.9 0.2 0.064 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 CBZ24720.1 - 0.037 13.4 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 CBZ24720.1 - 0.046 13.3 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 CBZ24720.1 - 0.049 12.5 0.1 0.086 11.7 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ATP_bind_1 PF03029.12 CBZ24720.1 - 0.057 12.9 0.1 0.22 11.0 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 CBZ24720.1 - 0.061 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CBZ24720.1 - 0.062 12.8 0.2 0.15 11.5 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Torsin PF06309.6 CBZ24720.1 - 0.068 13.0 0.1 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Torsin VirE PF05272.6 CBZ24720.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E Septin PF00735.13 CBZ24720.1 - 0.077 11.9 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_33 PF13671.1 CBZ24720.1 - 0.097 12.5 0.1 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.11 CBZ24720.1 - 0.13 11.3 0.3 0.19 10.8 0.2 1.6 1 1 0 1 1 1 0 AIG1 family zf-C3HC4_3 PF13920.1 CBZ24721.1 - 8.6e-06 25.3 9.4 2e-05 24.1 6.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ24721.1 - 1.5e-05 24.5 9.6 3.1e-05 23.5 6.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF1848 PF08902.6 CBZ24721.1 - 0.006 16.1 0.4 0.0083 15.6 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1848) HAUS-augmin3 PF14932.1 CBZ24721.1 - 0.0095 15.1 4.6 0.014 14.5 3.2 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 zf-C3HC4_2 PF13923.1 CBZ24721.1 - 0.01 15.8 11.4 0.021 14.8 7.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF972 PF06156.8 CBZ24721.1 - 0.011 16.0 2.2 0.021 15.1 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) zf-RING_2 PF13639.1 CBZ24721.1 - 0.025 14.4 11.2 0.09 12.6 7.9 1.9 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 CBZ24721.1 - 0.029 14.0 9.0 0.061 12.9 6.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CENP-F_leu_zip PF10473.4 CBZ24721.1 - 0.039 13.7 1.9 0.058 13.2 1.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-P11 PF03854.9 CBZ24721.1 - 0.059 12.8 9.2 0.11 11.9 6.4 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.1 CBZ24721.1 - 0.069 12.9 7.4 0.066 13.0 3.0 2.4 2 1 0 2 2 2 0 zf-RING of BARD1-type protein Peptidase_S46 PF10459.4 CBZ24721.1 - 0.071 11.5 3.0 0.094 11.1 2.0 1.0 1 0 0 1 1 1 0 Peptidase S46 IncA PF04156.9 CBZ24721.1 - 0.1 12.1 5.2 0.16 11.5 3.6 1.2 1 0 0 1 1 1 0 IncA protein zf-RING_4 PF14570.1 CBZ24721.1 - 0.23 11.0 8.5 0.44 10.1 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF724 PF05266.9 CBZ24721.1 - 0.27 10.8 2.5 0.4 10.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.4 CBZ24721.1 - 0.72 8.7 10.0 1.1 8.1 7.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 CBZ24721.1 - 1.1 8.1 4.0 1.6 7.6 2.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Prok-RING_4 PF14447.1 CBZ24721.1 - 3.7 7.1 8.3 13 5.4 5.7 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4200 PF13863.1 CBZ24722.1 - 3.6e-28 98.0 26.7 3.6e-28 98.0 18.5 3.3 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) Bromodomain PF00439.20 CBZ24722.1 - 0.073 12.9 1.5 0.16 11.9 0.1 2.3 2 1 1 3 3 3 0 Bromodomain HTH_26 PF13443.1 CBZ24722.1 - 0.2 11.8 2.1 2.7 8.2 0.4 2.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain Reo_sigmaC PF04582.7 CBZ24722.1 - 0.24 10.5 4.6 0.16 11.0 1.1 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DASH_Spc34 PF08657.5 CBZ24722.1 - 0.43 10.2 22.9 0.24 11.0 1.1 2.6 2 1 0 2 2 2 0 DASH complex subunit Spc34 Ribosomal_60s PF00428.14 CBZ24722.1 - 1.3 9.5 7.7 0.12 12.7 1.7 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Acetyltransf_1 PF00583.19 CBZ24724.1 - 2.5e-15 56.2 0.0 5e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CBZ24724.1 - 2.1e-07 30.5 0.0 4.8e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 CBZ24724.1 - 5.5e-05 23.2 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBZ24724.1 - 0.0021 18.0 0.1 0.0029 17.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBZ24724.1 - 0.0022 17.9 0.2 0.0032 17.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBZ24724.1 - 0.0078 16.3 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBZ24724.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ24724.1 - 0.019 14.8 0.8 0.029 14.2 0.1 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Tubulin PF00091.20 CBZ24726.1 - 3.3e-67 226.4 0.0 4.6e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ24726.1 - 6.6e-50 168.3 0.0 1.1e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBZ24726.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Tubulin PF00091.20 CBZ24727.1 - 3.3e-67 226.4 0.0 4.6e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ24727.1 - 6.6e-50 168.3 0.0 1.1e-49 167.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBZ24727.1 - 0.01 15.3 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 0 Tubulin domain Nipped-B_C PF12830.2 CBZ24728.1 - 4.4e-33 114.4 0.0 1.8e-32 112.5 0.0 2.1 1 1 0 1 1 1 1 Sister chromatid cohesion C-terminus AMP-binding PF00501.23 CBZ24730.1 - 3.3e-56 190.4 0.3 3.3e-56 190.4 0.2 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ24730.1 - 0.00071 20.4 0.4 0.0039 18.1 0.3 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain FeoA PF04023.9 CBZ24730.1 - 0.1 12.5 0.0 0.4 10.6 0.0 2.0 1 0 0 1 1 1 0 FeoA domain Radial_spoke PF04712.7 CBZ24731.1 - 2.4e-151 504.8 17.7 2.3e-114 382.8 4.5 2.0 1 1 1 2 2 2 2 Radial spokehead-like protein Pkinase PF00069.20 CBZ24732.1 - 1.9e-82 276.3 0.0 3.7e-82 275.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24732.1 - 8.9e-46 156.0 0.0 1.8e-45 155.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 CBZ24732.1 - 1.2e-11 44.7 0.1 5.1e-05 23.4 0.1 3.7 2 1 1 3 3 3 2 HEAT repeats Arm PF00514.18 CBZ24732.1 - 1.3e-10 40.6 5.0 9.5e-05 22.0 0.0 6.4 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 CBZ24732.1 - 5e-09 36.3 4.7 0.023 15.1 0.0 5.5 4 1 0 5 5 4 2 HEAT-like repeat HEAT PF02985.17 CBZ24732.1 - 9.4e-09 34.6 1.7 1.3 9.3 0.0 5.6 5 0 0 5 5 4 2 HEAT repeat Kinase-like PF14531.1 CBZ24732.1 - 3.2e-06 26.3 0.0 1.7e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CBZ24732.1 - 0.00015 21.1 1.1 0.0016 17.8 0.4 2.2 1 1 1 2 2 2 1 RIO1 family Arm_2 PF04826.8 CBZ24732.1 - 0.00042 19.4 0.2 0.0026 16.8 0.0 2.1 2 0 0 2 2 2 1 Armadillo-like YrbL-PhoP_reg PF10707.4 CBZ24732.1 - 0.00077 18.8 0.1 0.0015 17.8 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 CBZ24732.1 - 0.0039 16.9 0.0 0.041 13.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Proteasom_PSMB PF10508.4 CBZ24732.1 - 0.0075 14.5 1.6 0.011 13.9 0.1 2.0 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 CBZ24732.1 - 0.0088 15.9 1.0 0.11 12.3 0.0 2.9 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Seadorna_VP7 PF07387.6 CBZ24732.1 - 0.012 14.4 0.0 0.027 13.3 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 CBZ24732.1 - 0.014 14.4 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3361 PF11841.3 CBZ24732.1 - 0.025 14.3 0.2 2.3 7.9 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.3 CBZ24732.1 - 0.067 13.1 0.1 5.4 6.9 0.0 2.9 2 0 0 2 2 2 0 V-ATPase subunit H RIX1 PF08167.7 CBZ24732.1 - 0.085 12.5 1.3 1.1 8.8 0.0 3.3 3 1 1 4 4 3 0 rRNA processing/ribosome biogenesis Alba PF01918.16 CBZ24733.1 - 9.9e-14 50.7 0.4 9.9e-14 50.7 0.3 1.6 2 0 0 2 2 2 1 Alba Rpp20 PF12328.3 CBZ24733.1 - 0.0098 15.5 1.7 0.013 15.1 1.2 1.3 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Sigma_1_2 PF03084.9 CBZ24733.1 - 0.05 12.2 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 Reoviral Sigma1/Sigma2 family DUF4262 PF14081.1 CBZ24733.1 - 0.11 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) C2 PF00168.25 CBZ24734.1 - 0.0027 17.5 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 C2 domain DUF3773 PF12608.3 CBZ24734.1 - 0.033 14.2 0.1 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3773) TMF_TATA_bd PF12325.3 CBZ24736.1 - 1.2e-06 28.2 2.6 1.2e-06 28.2 1.8 5.6 2 1 3 5 5 5 2 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.4 CBZ24736.1 - 1.9e-05 24.5 55.4 0.3 10.9 1.1 6.1 3 1 3 6 6 6 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 CBZ24736.1 - 0.00053 19.5 55.6 0.0012 18.4 27.5 4.8 1 1 1 3 3 3 1 Intermediate filament protein Myosin_tail_1 PF01576.14 CBZ24736.1 - 0.0019 16.0 58.9 0.027 12.2 19.2 4.3 2 1 2 4 4 4 2 Myosin tail MscS_porin PF12795.2 CBZ24736.1 - 0.002 17.4 9.5 0.002 17.4 6.6 4.8 2 2 2 4 4 4 1 Mechanosensitive ion channel porin domain GAS PF13851.1 CBZ24736.1 - 0.0024 17.0 50.5 0.11 11.6 0.4 4.2 2 1 2 4 4 4 3 Growth-arrest specific micro-tubule binding RILP PF11461.3 CBZ24736.1 - 0.0047 17.0 2.6 0.0047 17.0 1.8 2.6 2 0 0 2 2 1 1 Rab interacting lysosomal protein LPP PF04728.8 CBZ24736.1 - 0.0054 16.4 3.2 2.1 8.2 0.4 4.0 4 0 0 4 4 3 1 Lipoprotein leucine-zipper Rootletin PF15035.1 CBZ24736.1 - 0.016 15.1 61.5 0.25 11.2 7.3 5.4 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 CBZ24736.1 - 0.028 13.6 20.1 0.18 10.9 0.8 3.3 1 1 1 3 3 3 0 Reovirus sigma C capsid protein Mnd1 PF03962.10 CBZ24736.1 - 0.067 12.8 50.4 0.13 11.8 7.5 5.1 2 1 3 5 5 5 0 Mnd1 family DivIC PF04977.10 CBZ24736.1 - 0.098 12.1 0.1 0.098 12.1 0.0 7.9 3 2 5 9 9 9 0 Septum formation initiator Atg14 PF10186.4 CBZ24736.1 - 0.16 10.9 53.9 0.022 13.7 9.4 3.7 2 1 2 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 CBZ24736.1 - 0.21 11.4 56.5 2.4 7.9 10.9 5.0 2 2 2 5 5 5 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.7 CBZ24736.1 - 0.22 11.3 21.0 1.6 8.5 3.8 4.0 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 CBZ24736.1 - 0.38 10.8 29.4 0.54 10.3 2.5 4.2 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 CBZ24736.1 - 0.53 10.3 40.2 2.6 8.1 0.2 6.3 2 1 4 7 7 7 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 CBZ24736.1 - 0.64 9.9 25.3 0.92 9.4 0.2 7.0 6 2 1 7 7 7 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 CBZ24736.1 - 0.93 9.7 19.6 4.2 7.7 1.1 5.3 4 2 1 5 5 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 CBZ24736.1 - 2.4 7.9 25.2 1.3 8.8 2.2 5.2 2 1 3 6 6 6 0 Protein of unknown function (DUF1664) IncA PF04156.9 CBZ24736.1 - 2.7 7.5 68.7 0.58 9.7 0.9 5.1 2 1 4 6 6 6 0 IncA protein DUF1045 PF06299.7 CBZ24736.1 - 7.2 6.2 13.4 0.14 11.7 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1045) DUF3972 PF13118.1 CBZ24736.1 - 8.2 6.5 21.5 1.4 9.0 2.9 4.0 3 2 1 4 4 4 0 Protein of unknown function (DUF3972) His_Phos_1 PF00300.17 CBZ24737.1 - 0.0039 17.2 0.0 0.0095 16.0 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sec63 PF02889.11 CBZ24738.1 - 7.2e-155 514.9 2.2 4.3e-91 305.4 0.6 2.8 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 CBZ24738.1 - 5.3e-53 178.9 0.0 2.8e-28 98.5 0.0 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CBZ24738.1 - 6.2e-22 78.3 0.0 8.6e-13 48.5 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBZ24738.1 - 1.3e-16 60.2 0.0 8.5e-08 31.9 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_19 PF13245.1 CBZ24738.1 - 7.9e-05 22.3 0.0 0.1 12.3 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_10 PF12846.2 CBZ24738.1 - 0.00012 21.6 0.4 1.4 8.2 0.0 4.5 4 1 0 5 5 5 1 AAA-like domain AAA_22 PF13401.1 CBZ24738.1 - 0.0003 20.9 1.2 0.13 12.4 0.1 3.7 3 2 0 3 3 2 1 AAA domain PhoH PF02562.11 CBZ24738.1 - 0.0011 18.2 0.1 0.092 11.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 CBZ24738.1 - 0.0023 16.9 0.0 2.5 6.9 0.0 2.9 3 0 0 3 3 3 2 Type II/IV secretion system protein DUF2075 PF09848.4 CBZ24738.1 - 0.016 14.2 0.0 0.047 12.6 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 CBZ24738.1 - 0.056 12.8 0.0 14 5.0 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF1014 PF06244.7 CBZ24740.1 - 3.8e-15 56.1 13.3 2e-14 53.8 7.7 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) DUF4355 PF14265.1 CBZ24740.1 - 0.23 11.4 23.7 0.53 10.2 16.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) F-protein PF00469.15 CBZ24740.1 - 0.52 9.6 7.0 0.92 8.8 4.9 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF3435 PF11917.3 CBZ24740.1 - 0.57 8.8 12.8 0.87 8.2 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Med5 PF08689.5 CBZ24740.1 - 3.8 5.0 5.3 5.1 4.6 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 DnaB_bind PF10410.4 CBZ24740.1 - 6.9 6.7 6.9 5.8 6.9 0.9 2.3 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase DUF3464 PF11947.3 CBZ24740.1 - 8.4 5.8 9.2 16 4.9 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) DUF179 PF02622.10 CBZ24743.1 - 2.7e-26 92.1 0.0 4.8e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Ribosomal_L18e PF00828.14 CBZ24744.1 - 1.5e-20 73.9 0.1 1.5e-20 73.9 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Ribosomal_L7Ae PF01248.21 CBZ24745.1 - 8.3e-23 79.7 1.4 1.1e-22 79.3 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Msg2_C PF12373.3 CBZ24745.1 - 0.053 12.7 0.2 0.15 11.2 0.1 1.8 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal Phage_NinH PF06322.6 CBZ24745.1 - 0.071 12.7 0.6 6.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Phage NinH protein DUF607 PF04678.8 CBZ24748.1 - 2.9e-14 53.4 0.2 3.8e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 Acetyltransf_1 PF00583.19 CBZ24749.1 - 3e-08 33.5 0.0 6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ24749.1 - 3.1e-05 24.0 0.0 6.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBZ24749.1 - 0.067 13.3 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 CBZ24749.1 - 0.11 13.0 0.4 7.8 7.1 0.0 2.7 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain APG6 PF04111.7 CBZ24750.1 - 0.26 10.2 4.1 0.43 9.5 2.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 NAD_binding_7 PF13241.1 CBZ24750.1 - 0.69 10.1 3.3 19 5.5 0.3 2.3 1 1 0 2 2 2 0 Putative NAD(P)-binding IBN_N PF03810.14 CBZ24752.1 - 0.00093 19.0 0.0 0.049 13.5 0.0 3.3 2 1 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 CBZ24752.1 - 0.0081 14.7 0.0 0.022 13.3 0.0 1.7 1 0 0 1 1 1 1 Cse1 SDA1 PF05285.7 CBZ24752.1 - 0.15 11.3 14.6 0.21 10.8 10.1 1.1 1 0 0 1 1 1 0 SDA1 HEAT PF02985.17 CBZ24752.1 - 0.18 11.9 4.1 0.28 11.3 0.3 3.6 3 0 0 3 3 3 0 HEAT repeat Daxx PF03344.10 CBZ24752.1 - 0.66 8.4 12.4 1 7.7 8.6 1.2 1 0 0 1 1 1 0 Daxx Family BSP_II PF05432.6 CBZ24752.1 - 2.1 7.5 14.0 3.6 6.7 9.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3138 PF11336.3 CBZ24752.1 - 6.6 4.7 7.5 0.21 9.7 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) zf-DHHC PF01529.15 CBZ24753.1 - 1.6e-37 128.6 1.4 1.9e-37 128.3 0.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase U-box PF04564.10 CBZ24754.1 - 9.9e-06 25.4 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain Lectin_leg-like PF03388.8 CBZ24755.1 - 1.5e-47 161.6 0.0 2.5e-47 160.9 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family PAT1 PF09770.4 CBZ24755.1 - 0.0034 15.7 55.4 0.0043 15.3 38.4 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CBZ24755.1 - 0.0074 16.2 38.8 0.01 15.7 26.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.3 CBZ24755.1 - 0.014 14.7 41.8 0.024 13.9 29.0 1.3 1 0 0 1 1 1 0 SprA-related family DUF605 PF04652.11 CBZ24755.1 - 0.046 13.1 31.1 0.066 12.5 21.6 1.2 1 0 0 1 1 1 0 Vta1 like Pox_A_type_inc PF04508.7 CBZ24755.1 - 0.071 12.9 2.5 0.16 11.7 1.7 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Med15 PF09606.5 CBZ24755.1 - 0.52 8.4 70.3 0.67 8.0 48.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Herpes_TAF50 PF03326.8 CBZ24755.1 - 2.1 7.1 36.0 2.9 6.7 25.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) V_ATPase_I PF01496.14 CBZ24755.1 - 2.6 5.7 14.6 3.1 5.5 10.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0560 PF10577.4 CBZ24755.1 - 6.2 4.9 24.1 13 3.8 16.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 AvrE PF11725.3 CBZ24755.1 - 8.4 3.2 27.3 11 2.9 19.0 1.0 1 0 0 1 1 1 0 Pathogenicity factor CRT10 PF08728.5 CBZ24755.1 - 8.5 4.2 10.9 12 3.7 7.6 1.2 1 0 0 1 1 1 0 CRT10 Peptidase_M24 PF00557.19 CBZ24756.1 - 3.8e-22 78.8 0.5 1.6e-21 76.8 0.3 2.2 1 1 0 1 1 1 1 Metallopeptidase family M24 PSP1 PF04468.7 CBZ24757.1 - 1.4e-24 85.8 0.0 3e-24 84.7 0.0 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Kinesin PF00225.18 CBZ24758.1 - 1e-34 119.7 0.0 2.1e-09 36.5 0.0 5.3 4 1 0 4 4 4 4 Kinesin motor domain ArfGap PF01412.13 CBZ24759.1 - 1.1e-28 99.3 0.1 1.8e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ADH_zinc_N PF00107.21 CBZ24760.1 - 7e-18 64.4 0.0 1.3e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBZ24760.1 - 2.4e-12 46.5 0.1 1.1e-11 44.4 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ubiquitin PF00240.18 CBZ24761.1 - 3.8e-08 32.5 0.0 8.4e-08 31.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ24761.1 - 0.00048 19.7 0.0 0.0013 18.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CBZ24761.1 - 0.0023 17.7 1.2 0.039 13.8 0.0 3.2 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBZ24761.1 - 0.017 15.3 0.0 0.076 13.2 0.0 2.1 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 CBZ24761.1 - 0.11 12.8 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Anoctamin PF04547.7 CBZ24762.1 - 6.6e-94 315.1 0.0 8e-94 314.8 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel C2 PF00168.25 CBZ24764.1 - 1.2e-16 60.2 0.2 4.1e-16 58.5 0.1 2.0 2 0 0 2 2 2 1 C2 domain YbjQ_1 PF01906.12 CBZ24764.1 - 0.00013 22.3 0.0 0.4 11.1 0.0 3.9 3 0 0 3 3 3 1 Putative heavy-metal-binding DSPc PF00782.15 CBZ24765.1 - 4.2e-08 32.8 0.1 8.7e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ24765.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Pkinase PF00069.20 CBZ24766.1 - 3.3e-41 141.1 0.0 2e-34 118.9 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24766.1 - 8.5e-17 61.0 0.0 8e-16 57.8 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ24766.1 - 0.0028 16.6 0.0 0.0067 15.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like DUF2392 PF10288.4 CBZ24767.1 - 9e-07 29.1 0.0 2.1e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) Complex1_LYR_2 PF13233.1 CBZ24770.1 - 5.3e-06 26.8 0.1 1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like DUF533 PF04391.7 CBZ24770.1 - 0.03 13.7 0.7 0.045 13.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Peptidase_M16 PF00675.15 CBZ24775.1 - 2.1e-07 30.8 1.4 0.0032 17.2 0.0 2.7 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBZ24775.1 - 3.8e-06 26.6 0.0 1.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Peptidase M16 inactive domain SpoIIID PF12116.3 CBZ24775.1 - 0.093 12.6 0.6 0.24 11.3 0.3 1.7 1 1 0 1 1 1 0 Stage III sporulation protein D LRR_6 PF13516.1 CBZ24779.1 - 1.1e-06 28.0 0.0 0.03 14.3 0.0 4.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 CBZ24779.1 - 2.8e-05 23.6 9.5 0.00012 21.6 1.4 2.0 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ24779.1 - 0.0017 18.1 2.9 0.1 12.6 0.4 2.9 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_8 PF13855.1 CBZ24779.1 - 0.13 12.0 3.2 0.62 9.8 2.0 2.3 1 1 1 2 2 2 0 Leucine rich repeat Ax_dynein_light PF10211.4 CBZ24780.1 - 4.9e-05 23.2 4.2 4.9e-05 23.2 2.9 2.4 2 0 0 2 2 2 1 Axonemal dynein light chain DUF4201 PF13870.1 CBZ24780.1 - 0.006 16.0 4.2 0.015 14.7 2.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) LRR19-TM PF15176.1 CBZ24780.1 - 0.033 13.8 0.1 0.12 12.0 0.1 1.9 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4557 PF15101.1 CBZ24780.1 - 0.04 13.7 1.0 0.092 12.5 0.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Spc7 PF08317.6 CBZ24780.1 - 0.055 12.1 1.8 0.1 11.2 1.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 CBZ24780.1 - 1.6 8.6 13.0 0.66 9.8 2.8 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Glyco_transf_25 PF01755.12 CBZ24781.1 - 7.9e-19 68.0 0.0 1.2e-17 64.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) TRM PF02005.11 CBZ24782.1 - 2.9e-93 312.7 0.0 8.6e-45 153.2 0.0 3.1 3 0 0 3 3 3 3 N2,N2-dimethylguanosine tRNA methyltransferase Actin PF00022.14 CBZ24783.1 - 5.5e-112 374.0 0.0 5.8e-111 370.6 0.0 1.9 1 1 0 1 1 1 1 Actin AAA PF00004.24 CBZ24784.1 - 2.2e-37 128.1 0.0 3.9e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ24784.1 - 6.6e-06 26.2 0.9 0.00027 21.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBZ24784.1 - 1.4e-05 24.2 0.0 2.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 CBZ24784.1 - 0.00013 21.4 0.3 0.13 11.6 0.2 2.5 1 1 1 2 2 2 2 AAA domain Vps4_C PF09336.5 CBZ24784.1 - 0.0004 20.2 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 CBZ24784.1 - 0.00085 18.1 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 CBZ24784.1 - 0.0012 18.5 0.2 0.0049 16.5 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain IstB_IS21 PF01695.12 CBZ24784.1 - 0.0013 18.1 0.1 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CBZ24784.1 - 0.0014 18.9 0.0 0.0056 16.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ24784.1 - 0.0024 17.8 0.4 0.014 15.4 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 CBZ24784.1 - 0.0052 17.5 0.0 0.012 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ24784.1 - 0.0054 16.4 0.0 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBZ24784.1 - 0.0097 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CBZ24784.1 - 0.011 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CBZ24784.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CBZ24784.1 - 0.018 14.1 0.1 0.55 9.3 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_24 PF13479.1 CBZ24784.1 - 0.021 14.4 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBZ24784.1 - 0.027 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain LisH PF08513.6 CBZ24784.1 - 0.027 14.2 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 LisH RNA_helicase PF00910.17 CBZ24784.1 - 0.032 14.4 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 CBZ24784.1 - 0.032 14.1 0.2 0.079 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CBZ24784.1 - 0.037 13.2 0.1 0.095 11.9 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein Mesothelin PF06060.7 CBZ24784.1 - 0.058 11.4 0.0 0.098 10.6 0.0 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) AAA_11 PF13086.1 CBZ24784.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain A_deaminase PF00962.17 CBZ24786.1 - 1.9e-76 257.1 0.0 2.1e-71 240.5 0.0 2.5 2 1 0 2 2 2 2 Adenosine/AMP deaminase Casein PF00363.13 CBZ24787.1 - 0.18 12.4 0.8 0.4 11.3 0.5 1.5 1 0 0 1 1 1 0 Casein ANTH PF07651.11 CBZ24787.1 - 0.52 8.9 3.8 1.5 7.4 0.4 2.3 2 0 0 2 2 2 0 ANTH domain BRCA2 PF00634.13 CBZ24788.1 - 0.04 13.2 0.3 0.084 12.1 0.2 1.5 1 0 0 1 1 1 0 BRCA2 repeat CAP59_mtransfer PF11735.3 CBZ24790.1 - 2.1e-75 253.0 0.0 3.4e-74 249.1 0.0 2.1 2 0 0 2 2 2 2 Cryptococcal mannosyltransferase 1 Peptidase_S8 PF00082.17 CBZ24792.1 - 1.5e-22 80.1 0.6 4.3e-22 78.5 0.4 1.8 1 0 0 1 1 1 1 Subtilase family RYDR_ITPR PF01365.16 CBZ24792.1 - 1.2 8.3 0.0 2.2 7.4 0.0 1.3 1 0 0 1 1 1 0 RIH domain Dpy-30 PF05186.8 CBZ24793.1 - 3.6e-08 32.7 0.4 6.6e-08 31.8 0.3 1.5 1 0 0 1 1 1 1 Dpy-30 motif NAD_binding_1 PF00175.16 CBZ24794.1 - 4.6e-28 97.9 0.0 6.3e-27 94.3 0.0 2.5 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBZ24794.1 - 1.2e-27 95.8 0.0 1.8e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CBZ24794.1 - 0.0012 18.8 0.0 0.025 14.4 0.0 2.2 1 1 0 2 2 2 1 Ferric reductase NAD binding domain AAA PF00004.24 CBZ24797.1 - 1.4e-42 144.9 0.0 2.4e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ24797.1 - 1.9e-06 28.0 0.2 0.00032 20.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ24797.1 - 2.6e-06 27.2 0.1 8.9e-06 25.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBZ24797.1 - 2.8e-06 27.3 0.0 5.5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBZ24797.1 - 3.5e-05 23.8 0.1 0.0014 18.6 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CBZ24797.1 - 0.0005 20.8 0.3 0.002 18.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 CBZ24797.1 - 0.00053 18.9 0.0 0.00083 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CBZ24797.1 - 0.0015 17.5 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBZ24797.1 - 0.004 16.8 0.4 0.0087 15.7 0.3 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CBZ24797.1 - 0.0049 17.1 0.1 0.011 16.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ24797.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ24797.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CBZ24797.1 - 0.0076 15.8 0.0 0.019 14.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBZ24797.1 - 0.017 15.1 0.1 0.039 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 CBZ24797.1 - 0.021 14.2 0.1 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 CBZ24797.1 - 0.021 14.9 0.0 0.059 13.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase KaiC PF06745.8 CBZ24797.1 - 0.029 13.5 0.3 0.26 10.3 0.1 2.1 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 CBZ24797.1 - 0.029 14.0 0.1 0.69 9.5 0.1 2.4 1 1 1 2 2 2 0 NACHT domain AAA_25 PF13481.1 CBZ24797.1 - 0.034 13.5 0.6 1.9 7.8 0.1 2.4 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CBZ24797.1 - 0.035 13.2 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 CBZ24797.1 - 0.047 12.5 0.0 0.093 11.5 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 CBZ24797.1 - 0.055 12.4 0.0 0.098 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 CBZ24797.1 - 0.069 12.7 1.2 0.33 10.5 0.1 2.5 4 0 0 4 4 4 0 AAA domain TIP49 PF06068.8 CBZ24797.1 - 0.081 11.6 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 CBZ24797.1 - 0.092 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI tRNA-synt_1 PF00133.17 CBZ24798.1 - 1.2e-26 92.9 0.0 1.7e-08 32.9 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CBZ24798.1 - 1.9e-21 76.1 0.0 5.3e-10 38.5 0.0 3.2 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CBZ24798.1 - 2.5e-12 46.8 0.9 4.3e-12 46.0 0.2 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CBZ24798.1 - 3.9e-07 29.4 0.0 1.7e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Pex19 PF04614.7 CBZ24798.1 - 0.25 10.9 1.2 3.2 7.2 0.2 2.3 2 0 0 2 2 2 0 Pex19 protein family P53 PF00870.13 CBZ24799.1 - 0.49 9.9 4.7 0.36 10.3 0.6 2.3 2 0 0 2 2 2 0 P53 DNA-binding domain RNA_pol_N PF01194.12 CBZ24800.1 - 7.9e-26 89.8 1.1 9.6e-26 89.5 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF155 PF02582.9 CBZ24801.1 - 6.8e-38 130.2 0.0 1e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF1664 PF07889.7 CBZ24801.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Abhydrolase_6 PF12697.2 CBZ24802.1 - 3.5e-24 85.9 4.6 9.6e-23 81.2 3.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ24802.1 - 1.9e-09 37.4 0.3 1.4e-08 34.6 0.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ24802.1 - 1e-08 35.0 0.0 0.0016 18.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.15 CBZ24802.1 - 5.3e-05 22.7 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 CBZ24802.1 - 0.027 14.0 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 CBZ24802.1 - 0.055 12.7 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydro_lipase PF04083.11 CBZ24802.1 - 0.063 12.6 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF2305 PF10230.4 CBZ24802.1 - 0.063 12.6 0.0 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 CBZ24802.1 - 0.065 12.1 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Endonuc-BglII PF09195.6 CBZ24803.1 - 0.085 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease BglII EF-hand_7 PF13499.1 CBZ24804.1 - 9.9e-16 57.6 0.2 8.3e-08 32.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ24804.1 - 7.4e-14 49.9 3.9 1.5e-07 30.1 0.0 3.7 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 CBZ24804.1 - 1.7e-12 46.7 2.0 5.7e-05 22.6 0.0 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 CBZ24804.1 - 9.6e-10 37.5 0.5 1.5e-05 24.5 0.1 3.8 2 1 2 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 CBZ24804.1 - 1e-07 30.9 0.6 7.4e-05 21.9 0.2 3.4 2 1 1 3 3 3 2 EF hand EF-hand_9 PF14658.1 CBZ24804.1 - 0.0031 17.3 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain DUF4192 PF13830.1 CBZ24804.1 - 0.014 15.0 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) EF-hand_4 PF12763.2 CBZ24804.1 - 0.076 12.7 0.1 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand MAM33 PF02330.11 CBZ24805.1 - 0.0009 19.0 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tctex-1 PF03645.8 CBZ24806.1 - 7.2e-26 90.0 0.0 8.6e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family QueF PF14489.1 CBZ24806.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein Rio2_N PF09202.6 CBZ24806.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Rio2, N-terminal Adenylsucc_synt PF00709.16 CBZ24807.1 - 2.1e-126 422.0 0.0 2.5e-126 421.7 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ribosomal_L27 PF01016.14 CBZ24808.1 - 0.039 13.7 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Ribosomal L27 protein Nucleoside_tran PF01733.13 CBZ24809.1 - 5.8e-31 107.7 0.6 2.4e-19 69.6 0.0 2.3 2 0 0 2 2 2 2 Nucleoside transporter Ribosomal_S4e PF00900.15 CBZ24810.1 - 1.2e-24 85.8 0.1 2.1e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 CBZ24810.1 - 1.9e-18 65.9 4.4 4.2e-18 64.9 3.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CBZ24810.1 - 8.9e-06 25.0 0.0 1.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CBZ24810.1 - 8.9e-05 22.0 0.3 0.0003 20.3 0.2 1.9 1 0 0 1 1 1 1 KOW motif Ribosomal_S4e PF00900.15 CBZ24811.1 - 5.7e-25 86.7 0.1 9.6e-25 86.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 CBZ24811.1 - 1e-18 66.8 3.4 2.3e-18 65.7 2.4 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CBZ24811.1 - 4.3e-06 26.0 0.0 9e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 CBZ24811.1 - 5.1e-05 22.8 0.3 0.00017 21.1 0.2 1.9 1 0 0 1 1 1 1 KOW motif TPK_catalytic PF04263.11 CBZ24812.1 - 1.5e-08 34.2 0.1 0.011 15.3 0.0 3.3 3 0 0 3 3 3 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 CBZ24812.1 - 2.6e-07 30.2 0.0 1.1e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF624 PF04854.9 CBZ24813.1 - 0.027 14.3 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF624 RDD PF06271.7 CBZ24813.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RDD family DUF4381 PF14316.1 CBZ24814.1 - 0.0015 18.6 0.2 0.0026 17.8 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) Herpes_gE PF02480.11 CBZ24814.1 - 0.0024 16.2 0.0 0.0033 15.7 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1510 PF07423.6 CBZ24814.1 - 0.027 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Shisa PF13908.1 CBZ24814.1 - 0.032 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 CBZ24814.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Pox_A9 PF04835.7 CBZ24814.1 - 0.15 11.9 0.4 0.25 11.2 0.3 1.2 1 0 0 1 1 1 0 A9 protein conserved region CDC45 PF02724.9 CBZ24814.1 - 2.5 6.0 5.8 3 5.7 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Endonuclease_NS PF01223.18 CBZ24815.1 - 3.1e-17 62.9 0.0 5.6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease ATP_bind_1 PF03029.12 CBZ24816.1 - 4.6e-63 212.9 0.0 1.7e-62 211.0 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 CBZ24816.1 - 2.8e-06 26.8 0.1 4.9e-06 26.0 0.0 1.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 CBZ24816.1 - 5.8e-06 25.8 0.0 0.00066 19.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 CBZ24816.1 - 1.8e-05 24.2 0.0 0.00035 20.0 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CBZ24816.1 - 8.6e-05 22.5 0.0 0.00028 20.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain ArgK PF03308.11 CBZ24816.1 - 0.00014 20.7 0.5 0.0053 15.5 0.0 3.1 2 2 0 2 2 2 1 ArgK protein MobB PF03205.9 CBZ24816.1 - 0.00029 20.5 0.1 0.00052 19.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CBZ24816.1 - 0.00039 20.3 0.1 0.00077 19.3 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.1 CBZ24816.1 - 0.00059 19.4 0.5 0.0013 18.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.1 CBZ24816.1 - 0.00071 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ24816.1 - 0.00092 18.9 0.1 0.0037 16.9 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain cobW PF02492.14 CBZ24816.1 - 0.001 18.5 0.3 0.21 11.0 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 CBZ24816.1 - 0.002 17.4 0.0 0.17 11.0 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Zeta_toxin PF06414.7 CBZ24816.1 - 0.0022 17.1 0.0 0.0046 16.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 CBZ24816.1 - 0.003 17.7 0.0 0.0071 16.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain Miro PF08477.8 CBZ24816.1 - 0.0038 17.7 0.3 0.11 13.0 0.2 2.4 1 1 0 1 1 1 1 Miro-like protein AAA_33 PF13671.1 CBZ24816.1 - 0.0039 17.0 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CBZ24816.1 - 0.0064 15.3 0.1 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 CBZ24816.1 - 0.0068 16.0 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 CBZ24816.1 - 0.007 17.1 0.0 0.014 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 CBZ24816.1 - 0.018 14.0 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SRPRB PF09439.5 CBZ24816.1 - 0.021 14.0 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 CBZ24816.1 - 0.022 13.9 0.1 0.43 9.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF258 DLIC PF05783.6 CBZ24816.1 - 0.025 13.2 0.1 0.52 8.9 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) MipZ PF09140.6 CBZ24816.1 - 0.035 13.2 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ NTPase_1 PF03266.10 CBZ24816.1 - 0.035 13.8 0.1 0.12 12.0 0.1 1.9 1 1 0 1 1 1 0 NTPase IstB_IS21 PF01695.12 CBZ24816.1 - 0.035 13.5 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein APS_kinase PF01583.15 CBZ24816.1 - 0.036 13.7 0.1 0.082 12.5 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase Torsin PF06309.6 CBZ24816.1 - 0.041 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Torsin Ras PF00071.17 CBZ24816.1 - 0.052 12.9 0.2 3.7 6.9 0.0 2.6 3 1 0 3 3 2 0 Ras family G-alpha PF00503.15 CBZ24816.1 - 0.058 12.0 0.0 1.9 7.1 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_35 PF14516.1 CBZ24816.1 - 0.061 11.9 0.0 0.13 10.8 0.0 1.4 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 CBZ24816.1 - 0.075 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 CBZ24816.1 - 0.079 13.1 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CBZ24816.1 - 0.083 12.3 0.1 0.48 9.9 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 CBZ24816.1 - 0.093 11.7 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain DUF2075 PF09848.4 CBZ24816.1 - 0.094 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 CBZ24816.1 - 0.11 11.9 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.13 CBZ24816.1 - 0.14 11.1 0.3 0.84 8.5 0.2 2.2 1 1 0 1 1 1 0 Septin Complex1_LYR PF05347.10 CBZ24818.1 - 4e-07 29.7 0.1 9.9e-07 28.4 0.1 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBZ24818.1 - 1.7e-06 28.1 0.3 4.1e-06 26.9 0.2 1.8 1 1 0 1 1 1 1 Complex1_LYR-like DUF3733 PF12534.3 CBZ24819.1 - 0.12 11.7 0.1 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 DUF3753 PF12575.3 CBZ24819.1 - 0.3 10.9 0.1 0.3 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Conotoxin PF02950.12 CBZ24819.1 - 0.31 11.8 1.8 0.31 11.8 0.1 1.8 2 0 0 2 2 2 0 Conotoxin Shisa PF13908.1 CBZ24820.1 - 0.00014 22.0 0.3 0.00028 21.1 0.2 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4492 PF14899.1 CBZ24820.1 - 0.016 14.6 0.8 0.03 13.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) GP41 PF00517.12 CBZ24820.1 - 0.031 13.8 0.9 0.052 13.1 0.6 1.2 1 0 0 1 1 1 0 Retroviral envelope protein DUF1183 PF06682.7 CBZ24820.1 - 0.039 13.5 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Rhabdo_glycop PF00974.13 CBZ24820.1 - 0.068 11.3 1.1 0.1 10.8 0.8 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF3753 PF12575.3 CBZ24820.1 - 1.7 8.4 5.2 3.2 7.6 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) SOBP PF15279.1 CBZ24821.1 - 0.046 14.1 0.8 10 6.3 0.1 2.2 2 0 0 2 2 2 0 Sine oculis-binding protein MIF4G_like_2 PF09090.6 CBZ24822.1 - 1 8.5 4.2 0.96 8.6 0.4 2.1 2 0 0 2 2 2 0 MIF4G like NPV_P10 PF05531.7 CBZ24822.1 - 3.9 7.7 7.0 15 5.8 3.0 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Dpy-30 PF05186.8 CBZ24823.1 - 6.6e-13 47.9 0.6 1.5e-12 46.7 0.4 1.7 1 0 0 1 1 1 1 Dpy-30 motif AAA_17 PF13207.1 CBZ24823.1 - 1.7e-08 35.3 0.0 7.7e-08 33.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ24823.1 - 0.017 15.0 0.0 0.34 10.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CBZ24823.1 - 0.18 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sin_N PF04801.8 CBZ24825.1 - 7e-61 206.3 0.0 1.4e-60 205.3 0.0 1.4 2 0 0 2 2 2 1 Sin-like protein conserved region Botulinum_HA-17 PF05588.6 CBZ24825.1 - 0.19 11.5 0.0 9.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Clostridium botulinum HA-17 protein EMP70 PF02990.11 CBZ24826.1 - 3.2e-91 306.3 24.1 3.2e-91 306.3 16.7 2.2 2 1 0 2 2 2 1 Endomembrane protein 70 Lactamase_B_2 PF12706.2 CBZ24827.1 - 7e-28 97.4 0.5 1.1e-27 96.8 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CBZ24827.1 - 2e-13 50.3 0.1 2e-12 47.1 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBZ24827.1 - 0.0095 15.6 0.0 0.05 13.2 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily WD40 PF00400.27 CBZ24828.1 - 0.00015 21.4 0.8 0.37 10.7 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF2217 PF10265.4 CBZ24829.1 - 2.2 6.9 7.8 3.9 6.1 5.4 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Utp12 PF04003.7 CBZ24830.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family Peptidase_M32 PF02074.10 CBZ24830.1 - 0.13 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase LRR_4 PF12799.2 CBZ24831.1 - 1.6e-11 43.5 1.1 6.3e-07 28.8 0.2 3.3 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24831.1 - 4.9e-07 29.4 15.2 8.2e-05 22.2 1.2 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CBZ24831.1 - 0.00034 20.3 5.3 0.3 11.3 0.3 4.0 3 1 1 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 CBZ24831.1 - 0.0009 18.9 7.3 6.8 7.1 0.0 4.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 CBZ24831.1 - 0.0011 18.7 5.2 0.99 9.8 0.0 4.0 3 0 0 3 3 3 2 Leucine rich repeat EF-hand_1 PF00036.27 CBZ24833.1 - 8.5e-20 68.4 0.2 0.001 18.1 0.0 5.5 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 CBZ24833.1 - 3e-19 68.9 3.5 7.9e-11 41.9 0.0 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CBZ24833.1 - 4.9e-16 57.1 6.3 0.0016 18.1 0.0 5.3 5 0 0 5 5 5 5 EF-hand domain EF-hand_5 PF13202.1 CBZ24833.1 - 1.8e-15 55.4 1.1 0.00023 20.3 0.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CBZ24833.1 - 1.4e-11 43.8 1.5 0.00039 19.9 0.0 5.1 3 1 1 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.27 CBZ24834.1 - 8e-24 81.0 0.1 1.3e-05 24.1 0.0 5.2 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.1 CBZ24834.1 - 4.6e-21 72.7 0.7 0.00023 20.7 0.0 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 CBZ24834.1 - 4.6e-21 74.7 0.1 2.2e-09 37.2 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 CBZ24834.1 - 3.5e-17 61.7 0.2 9.9e-07 28.2 0.0 4.7 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.1 CBZ24834.1 - 5.4e-14 50.7 0.4 9.1e-06 24.7 0.0 4.0 4 0 0 4 4 4 3 EF hand Phage_T4_Ndd PF06591.6 CBZ24834.1 - 0.028 13.9 0.2 0.039 13.5 0.2 1.3 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) TerB PF05099.8 CBZ24834.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB HECT PF00632.20 CBZ24835.1 - 2.4e-45 155.0 0.0 5.1e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CBZ24835.1 - 3e-23 82.2 1.8 2.5e-09 37.2 0.0 3.7 3 0 0 3 3 3 3 SPRY domain Ran_BP1 PF00638.13 CBZ24836.1 - 5.1e-26 91.1 1.3 6.8e-26 90.7 0.9 1.1 1 0 0 1 1 1 1 RanBP1 domain Polyketide_cyc2 PF10604.4 CBZ24836.1 - 0.014 15.5 0.2 0.017 15.2 0.2 1.2 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport WH1 PF00568.18 CBZ24836.1 - 0.03 14.0 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 WH1 domain Lactamase_B_2 PF12706.2 CBZ24837.1 - 7.8e-05 22.2 0.1 0.00093 18.7 0.1 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DRMBL PF07522.9 CBZ24837.1 - 0.0026 17.7 0.0 0.0081 16.1 0.0 1.8 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 CBZ24837.1 - 0.0048 16.5 0.6 0.045 13.4 0.4 2.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily PIN_4 PF13638.1 CBZ24838.1 - 2.1e-18 66.7 0.0 3.7e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 PIN domain Metallophos PF00149.23 CBZ24839.1 - 1.1e-27 96.7 0.0 1.6e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AAA PF00004.24 CBZ24840.1 - 3.7e-18 65.9 0.0 9.6e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBZ24840.1 - 0.0037 16.6 0.1 0.11 11.9 0.1 2.6 1 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ24840.1 - 0.0062 16.2 2.0 0.1 12.3 0.0 3.5 3 1 0 3 3 3 1 Part of AAA domain RuvB_N PF05496.7 CBZ24840.1 - 0.0067 15.5 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBZ24840.1 - 0.013 15.5 0.0 0.06 13.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBZ24840.1 - 0.017 15.8 0.1 0.095 13.5 0.0 2.4 2 1 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CBZ24840.1 - 0.026 14.0 1.5 0.08 12.4 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_16 PF13191.1 CBZ24840.1 - 0.04 13.9 0.0 0.04 13.9 0.0 4.2 4 1 1 5 5 5 0 AAA ATPase domain AAA_5 PF07728.9 CBZ24840.1 - 0.077 12.7 0.0 0.31 10.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBZ24840.1 - 0.088 12.9 0.0 0.55 10.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 CBZ24840.1 - 0.16 11.9 0.0 0.79 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain FoP_duplication PF13865.1 CBZ24840.1 - 9.1 6.8 9.7 0.93 9.9 2.3 2.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 E1-E2_ATPase PF00122.15 CBZ24841.1 - 1.7e-21 76.3 0.0 5.9e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CBZ24841.1 - 5.7e-13 49.7 0.0 7.1e-12 46.1 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ24841.1 - 8.1e-13 48.9 0.0 2.7e-12 47.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ24841.1 - 3.1e-10 39.8 0.0 1.3e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBZ24841.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NIF PF03031.13 CBZ24842.1 - 0.025 14.2 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Gtr1_RagA PF04670.7 CBZ24844.1 - 1.7e-90 302.2 0.0 2.3e-90 301.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CBZ24844.1 - 4.7e-05 22.8 0.0 0.00011 21.5 0.0 1.6 2 0 0 2 2 2 1 Ras family Arf PF00025.16 CBZ24844.1 - 0.00014 21.1 0.0 0.00086 18.5 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 CBZ24844.1 - 0.0068 16.8 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein RuvB_N PF05496.7 CBZ24844.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 CBZ24844.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Metallophos PF00149.23 CBZ24845.1 - 2.1e-27 95.8 0.0 3.3e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UQ_con PF00179.21 CBZ24846.1 - 1.7e-14 53.4 0.0 1.9e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBZ24846.1 - 0.0018 18.1 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain Tcp10_C PF07202.8 CBZ24847.1 - 1.4e-28 99.6 0.1 2.8e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 T-complex protein 10 C-terminus HALZ PF02183.13 CBZ24847.1 - 0.0041 16.7 3.5 0.0098 15.5 0.3 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper MORN_2 PF07661.8 CBZ24847.1 - 0.046 13.7 0.0 3.4 7.9 0.0 3.1 2 0 0 2 2 2 0 MORN repeat variant CAF-1_p150 PF11600.3 CBZ24847.1 - 0.99 8.7 40.2 0.76 9.1 11.5 2.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Kinesin PF00225.18 CBZ24849.1 - 8.8e-93 310.6 0.0 1.2e-92 310.2 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain SAM_1 PF00536.25 CBZ24849.1 - 8.1e-05 22.7 3.3 0.00017 21.6 0.2 2.4 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 CBZ24849.1 - 0.063 13.1 0.2 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SE PF08491.5 CBZ24850.1 - 3.6e-61 206.4 0.0 5.3e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 CBZ24850.1 - 3.4e-08 32.9 0.0 5.8e-07 28.8 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 CBZ24850.1 - 0.00076 18.4 0.1 0.95 8.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CBZ24850.1 - 0.0044 16.9 0.4 0.014 15.2 0.1 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ24850.1 - 0.014 15.4 0.1 0.043 13.8 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GDI PF00996.13 CBZ24850.1 - 0.026 12.8 0.0 0.038 12.3 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_oxidored PF12831.2 CBZ24850.1 - 0.1 11.6 0.1 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBZ24850.1 - 0.11 11.3 0.1 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 CBZ24850.1 - 0.12 11.2 0.1 0.27 10.0 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 CBZ24850.1 - 0.13 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DNA_pol_A PF00476.15 CBZ24851.1 - 4.6e-32 111.0 0.4 1.2e-31 109.6 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 CBZ24851.1 - 0.002 17.6 0.0 0.0058 16.1 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease Pkinase PF00069.20 CBZ24852.1 - 7.4e-52 176.0 0.0 1.3e-48 165.4 0.0 3.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24852.1 - 3.1e-21 75.6 0.0 1.8e-17 63.3 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ24852.1 - 0.00018 20.5 0.0 0.00061 18.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBZ24852.1 - 0.0046 16.7 0.1 0.019 14.6 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Dynein_heavy PF03028.10 CBZ24853.1 - 3.3e-233 775.8 0.0 9.1e-174 579.3 0.0 2.4 2 0 0 2 2 2 2 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CBZ24853.1 - 1e-114 381.8 0.1 3.7e-114 380.0 0.1 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N2 PF08393.8 CBZ24853.1 - 2.8e-108 362.0 2.0 8.1e-108 360.5 0.1 3.0 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CBZ24853.1 - 1.1e-106 357.4 0.1 1.1e-106 357.4 0.0 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.2 CBZ24853.1 - 2.1e-93 312.1 0.3 5.8e-93 310.7 0.1 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 CBZ24853.1 - 7.3e-87 291.3 11.2 1.7e-86 290.1 7.8 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBZ24853.1 - 1.1e-86 290.3 0.7 3e-86 288.8 0.5 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 CBZ24853.1 - 9.1e-85 283.1 0.1 2.1e-84 281.9 0.1 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CBZ24853.1 - 7.2e-22 77.6 0.0 1.4e-07 31.3 0.0 5.6 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ24853.1 - 6.3e-09 36.0 0.0 0.084 12.8 0.0 6.0 5 0 0 5 5 5 2 AAA ATPase domain AAA PF00004.24 CBZ24853.1 - 2.6e-06 27.6 0.0 0.13 12.4 0.0 3.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ24853.1 - 1.1e-05 25.6 0.3 3.8 7.6 0.0 5.7 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 CBZ24853.1 - 0.00019 21.7 0.1 6.4 7.0 0.0 5.7 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 CBZ24853.1 - 0.00044 19.9 1.9 11 5.8 0.0 3.9 4 0 0 4 4 3 0 Part of AAA domain AAA_17 PF13207.1 CBZ24853.1 - 0.0023 18.7 0.1 0.68 10.7 0.0 5.1 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.16 CBZ24853.1 - 0.0036 16.4 0.3 0.59 9.2 0.0 3.9 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 CBZ24853.1 - 0.012 15.2 0.4 26 4.4 0.0 3.7 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Reo_sigmaC PF04582.7 CBZ24853.1 - 0.055 12.6 9.3 0.11 11.6 0.1 3.8 4 0 0 4 4 4 0 Reovirus sigma C capsid protein MutS_III PF05192.13 CBZ24853.1 - 0.92 9.2 11.8 6.1 6.5 0.0 6.4 5 3 0 5 5 4 0 MutS domain III Cpn60_TCP1 PF00118.19 CBZ24854.1 - 4e-146 487.4 3.3 4.5e-146 487.2 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L44 PF00935.14 CBZ24855.1 - 2.8e-31 107.3 8.9 4.4e-31 106.7 6.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 RPA_interact_C PF14768.1 CBZ24855.1 - 0.11 12.9 0.7 0.66 10.4 0.5 1.9 1 1 0 1 1 1 0 Replication protein A interacting C-terminal P5CR_dimer PF14748.1 CBZ24856.1 - 1.8e-37 127.6 1.5 2.8e-37 126.9 1.0 1.3 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CBZ24856.1 - 3.8e-16 59.2 0.0 7.9e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CBZ24856.1 - 9.1e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 CBZ24856.1 - 0.00027 20.3 0.0 0.00049 19.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 CBZ24856.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 CBZ24856.1 - 0.0021 17.8 1.6 0.037 13.7 1.1 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 CBZ24856.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PDH PF02153.12 CBZ24856.1 - 0.038 12.8 0.1 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase IlvN PF07991.7 CBZ24856.1 - 0.041 13.2 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain MFS_1 PF07690.11 CBZ24857.1 - 3.4e-17 62.2 35.5 8.1e-15 54.3 18.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CBZ24857.1 - 1e-09 38.0 16.8 1e-09 38.0 11.6 2.8 2 1 0 2 2 2 1 Nodulin-like LRR_4 PF12799.2 CBZ24858.1 - 3.5e-14 52.0 0.0 0.0022 17.5 0.0 6.3 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ24858.1 - 0.00033 20.3 0.5 0.66 9.7 0.0 4.8 3 2 2 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 CBZ24858.1 - 0.0006 19.6 1.8 6.6 7.1 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.28 CBZ24858.1 - 0.0043 16.8 2.0 7.9 6.9 0.2 4.4 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ24858.1 - 0.026 14.6 4.2 60 4.5 0.1 5.0 3 1 1 4 4 4 0 Leucine rich repeat YlbD_coat PF14071.1 CBZ24859.1 - 0.0039 17.2 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Putative coat protein EXOSC1 PF10447.4 CBZ24859.1 - 0.1 12.5 0.1 1.1 9.2 0.1 2.3 1 1 1 2 2 2 0 Exosome component EXOSC1/CSL4 PI3Ka PF00613.15 CBZ24860.1 - 2.4e-46 157.2 2.1 4.5e-46 156.3 1.5 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CBZ24860.1 - 2.1e-45 155.0 0.0 3.5e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CBZ24860.1 - 2.1e-09 37.2 0.0 4.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 CBZ24860.1 - 2.4e-09 37.0 0.0 1.8e-08 34.2 0.0 2.3 3 0 0 3 3 3 1 PI3-kinase family, ras-binding domain Tet_JBP PF12851.2 CBZ24862.1 - 6.3e-24 84.1 0.4 1.2e-23 83.2 0.1 1.7 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily SNF2_N PF00176.18 CBZ24862.1 - 9.9e-24 83.6 0.0 1.8e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ24862.1 - 5.2e-13 48.6 0.1 1e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ24862.1 - 8.3e-06 25.7 0.0 3.2e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBZ24862.1 - 0.0067 15.9 0.0 0.018 14.5 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF2095 PF09868.4 CBZ24862.1 - 0.033 13.9 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) cNMP_binding PF00027.24 CBZ24863.1 - 9.9e-06 25.2 0.0 0.18 11.6 0.0 3.8 3 2 0 3 3 3 2 Cyclic nucleotide-binding domain Arf PF00025.16 CBZ24864.1 - 5.2e-05 22.5 0.0 0.00012 21.3 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_28 PF13521.1 CBZ24864.1 - 0.0083 16.1 0.3 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 AAA domain zf-DHHC PF01529.15 CBZ24865.1 - 2.2e-25 89.0 11.1 2.2e-25 89.0 7.7 1.7 2 1 0 2 2 2 1 DHHC palmitoyltransferase TAT_signal PF10518.4 CBZ24865.1 - 0.73 9.9 0.0 0.73 9.9 0.0 3.1 4 0 0 4 4 4 0 TAT (twin-arginine translocation) pathway signal sequence Yip1 PF04893.12 CBZ24865.1 - 5.7 6.4 17.3 0.75 9.2 3.2 2.8 2 1 1 3 3 3 0 Yip1 domain PRP1_N PF06424.7 CBZ24866.1 - 0.025 14.8 0.1 0.025 14.8 0.0 1.8 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DnaJ PF00226.26 CBZ24867.1 - 1.8e-05 24.3 0.0 4.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain CH PF00307.26 CBZ24868.1 - 0.0034 17.4 0.0 0.012 15.6 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain DivIC PF04977.10 CBZ24868.1 - 1.5 8.3 9.5 0.71 9.3 4.1 2.4 2 0 0 2 2 2 0 Septum formation initiator DnaJ PF00226.26 CBZ24869.1 - 2.1e-14 52.9 0.6 3.7e-14 52.2 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain IU_nuc_hydro PF01156.14 CBZ24871.1 - 2.9e-70 236.9 0.1 3.4e-70 236.7 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase CAP59_mtransfer PF11735.3 CBZ24871.1 - 0.11 11.6 0.1 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 MOZ_SAS PF01853.13 CBZ24872.1 - 3.4e-63 212.3 0.0 4.9e-63 211.7 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CBZ24872.1 - 1.2e-08 34.5 0.0 2.9e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 CBZ24872.1 - 0.011 15.7 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF4286 PF14114.1 CBZ24872.1 - 0.034 14.4 0.3 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) zf-Di19 PF05605.7 CBZ24872.1 - 1 9.5 5.9 4.5 7.4 0.6 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L12 PF00542.14 CBZ24873.1 - 7.5e-17 61.1 2.5 1.4e-16 60.1 1.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 CBZ24873.1 - 0.018 15.4 6.8 0.018 15.4 4.7 2.3 1 1 1 2 2 2 0 60s Acidic ribosomal protein Chromo PF00385.19 CBZ24874.1 - 0.0068 16.0 0.2 0.0068 16.0 0.2 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Thioredoxin_8 PF13905.1 CBZ24877.1 - 1.4e-07 31.5 0.1 2.2e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBZ24877.1 - 3.2e-05 23.5 0.1 4.2e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBZ24877.1 - 0.00036 20.0 0.1 0.00045 19.7 0.1 1.1 1 0 0 1 1 1 1 Redoxin BBIP10 PF14777.1 CBZ24878.1 - 1e-13 50.4 0.9 1.6e-13 49.8 0.6 1.3 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 Pol_alpha_B_N PF08418.5 CBZ24878.1 - 3.5 7.1 10.5 7.6 5.9 7.3 1.6 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF4201 PF13870.1 CBZ24879.1 - 2.8e-31 108.3 10.4 2.8e-31 108.3 7.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) K_channel_TID PF07941.6 CBZ24879.1 - 0.05 13.8 0.3 0.05 13.8 0.2 3.2 4 0 0 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain DivIVA PF05103.8 CBZ24879.1 - 0.22 11.5 21.5 0.045 13.7 3.5 3.3 3 0 0 3 3 3 0 DivIVA protein DUF1675 PF07897.6 CBZ24879.1 - 0.52 10.1 5.2 0.19 11.5 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1675) TACC PF05010.9 CBZ24879.1 - 5.9 6.5 16.8 0.025 14.3 0.8 2.6 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) TMF_DNA_bd PF12329.3 CBZ24879.1 - 8.1 6.3 12.1 1.9 8.3 1.7 3.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Rho_Binding PF08912.6 CBZ24879.1 - 9.9 6.5 14.5 4.5 7.6 1.8 4.2 3 1 1 4 4 4 0 Rho Binding PX PF00787.19 CBZ24880.1 - 3.1e-10 39.8 0.0 3.6e-09 36.4 0.0 2.4 2 0 0 2 2 2 1 PX domain Sec5 PF15469.1 CBZ24881.1 - 4.9e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 DUF1510 PF07423.6 CBZ24881.1 - 0.16 11.3 5.5 0.33 10.2 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HIT PF01230.18 CBZ24882.1 - 2.7e-22 79.1 0.1 3.5e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CBZ24882.1 - 1.6e-15 57.3 0.0 2e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CBZ24882.1 - 0.054 13.1 5.6 0.094 12.3 2.5 2.3 2 1 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 TRAP-gamma PF07074.7 CBZ24883.1 - 1.3e-07 31.3 2.8 0.003 17.0 0.1 2.1 2 0 0 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) OPT PF03169.10 CBZ24883.1 - 0.048 12.0 0.8 0.069 11.5 0.5 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein MARVEL PF01284.18 CBZ24883.1 - 0.085 12.6 2.7 0.14 11.9 1.9 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF4386 PF14329.1 CBZ24883.1 - 0.095 12.1 2.0 0.3 10.5 1.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4386) Cytochrom_B_N PF00033.14 CBZ24883.1 - 0.11 11.8 1.3 0.18 11.1 0.9 1.4 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF2721 PF11026.3 CBZ24883.1 - 0.23 11.1 2.3 0.23 11.0 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) VWA_3 PF13768.1 CBZ24884.1 - 3.1e-09 36.7 0.3 7.6e-09 35.4 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 CBZ24884.1 - 2.2e-05 24.6 0.8 3.6e-05 23.9 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Na_Ca_ex PF01699.19 CBZ24885.1 - 1.5e-08 34.3 22.9 6.5e-05 22.5 7.2 3.0 2 1 1 3 3 3 2 Sodium/calcium exchanger protein adh_short PF00106.20 CBZ24887.1 - 0.0048 16.8 0.3 0.0096 15.8 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase DUF4404 PF14357.1 CBZ24887.1 - 0.047 14.1 0.3 0.91 9.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) RmlD_sub_bind PF04321.12 CBZ24887.1 - 0.053 12.3 0.7 0.37 9.6 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Proteasome PF00227.21 CBZ24889.1 - 2.2e-50 170.6 0.0 2.9e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ24889.1 - 8.5e-14 50.5 0.4 1.5e-13 49.7 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2064 PF09837.4 CBZ24889.1 - 0.15 11.6 0.7 0.75 9.4 0.0 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2064) AA_permease_2 PF13520.1 CBZ24890.1 - 2.7e-34 118.4 41.0 3.9e-34 117.9 28.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CBZ24890.1 - 5.2e-14 51.4 36.5 1.5e-13 49.9 25.3 1.7 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 CBZ24891.1 - 1.1e-20 73.5 20.7 1.6e-20 73.0 14.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IPK PF03770.11 CBZ24892.1 - 7.1e-43 146.5 0.2 1.2e-42 145.8 0.1 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Thr_synth_N PF14821.1 CBZ24893.1 - 8.9e-14 51.2 0.4 4e-13 49.1 0.0 2.4 4 0 0 4 4 4 1 Threonine synthase N terminus PALP PF00291.20 CBZ24893.1 - 7.9e-12 45.0 0.0 1.9e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-CW PF07496.10 CBZ24894.1 - 0.00016 21.2 2.1 0.00038 20.1 1.4 1.6 1 0 0 1 1 1 1 CW-type Zinc Finger Bromodomain PF00439.20 CBZ24894.1 - 0.25 11.3 0.0 6.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Bromodomain Adeno_hexon PF01065.14 CBZ24894.1 - 0.3 9.8 0.0 0.57 8.9 0.0 1.4 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain zf-DNL PF05180.7 CBZ24894.1 - 0.46 10.2 2.0 0.55 9.9 0.4 1.8 1 1 1 2 2 2 0 DNL zinc finger Choline_transpo PF04515.7 CBZ24896.1 - 8.1e-73 245.0 42.0 8.1e-73 245.0 29.1 2.0 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF1253 PF06862.7 CBZ24901.1 - 6.9e-124 413.6 0.1 9.6e-124 413.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Dzip-like_N PF13815.1 CBZ24902.1 - 1.2e-37 128.2 3.2 1.2e-37 128.2 2.2 2.6 3 0 0 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-Di19 PF05605.7 CBZ24902.1 - 0.00022 21.3 0.2 0.00043 20.3 0.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CBZ24902.1 - 0.048 14.0 1.0 0.11 12.8 0.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CBZ24902.1 - 0.054 13.8 1.5 0.1 12.9 1.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 CBZ24902.1 - 0.09 12.8 0.6 0.51 10.4 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF2972 PF11186.3 CBZ24902.1 - 0.21 11.4 0.4 0.35 10.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) APC_CDC26 PF10471.4 CBZ24902.1 - 0.28 11.9 0.0 0.28 11.9 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit 1 mRNA_triPase PF02940.10 CBZ24903.1 - 6.1e-11 42.4 0.0 3.4e-09 36.7 0.0 2.7 2 1 0 2 2 2 1 mRNA capping enzyme, beta chain Pyr_redox_2 PF07992.9 CBZ24904.1 - 5.5e-11 42.7 0.0 1.5e-06 28.2 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ24904.1 - 3.4e-10 40.1 0.0 1.2e-06 28.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CBZ24904.1 - 1.6e-06 27.3 0.0 0.005 15.8 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 CBZ24904.1 - 1.5e-05 24.0 0.0 0.024 13.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CBZ24904.1 - 1.7e-05 24.9 0.0 0.00042 20.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CBZ24904.1 - 2.2e-05 24.2 0.1 0.088 12.5 0.0 3.7 4 0 0 4 4 4 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 CBZ24904.1 - 0.00012 22.0 0.0 0.73 9.9 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CBZ24904.1 - 0.00066 18.7 0.0 0.0028 16.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 CBZ24904.1 - 0.0051 17.0 0.0 1.2 9.4 0.0 2.6 3 0 0 3 3 2 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 CBZ24904.1 - 0.0085 15.8 0.0 0.022 14.4 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 CBZ24904.1 - 0.015 14.9 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 CBZ24904.1 - 0.058 12.4 0.1 0.81 8.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 CBZ24904.1 - 0.06 12.4 0.0 1.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 CBZ24904.1 - 0.094 12.0 0.0 4.9 6.4 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 CBZ24904.1 - 0.12 11.1 0.0 11 4.7 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A TrkA_N PF02254.13 CBZ24904.1 - 0.14 12.1 0.0 11 6.0 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Nudc_N PF14050.1 CBZ24905.1 - 5.4e-19 67.8 0.3 1.5e-18 66.4 0.2 1.8 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. CS PF04969.11 CBZ24905.1 - 4.6e-17 62.3 0.1 8.4e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 CS domain KTI12 PF08433.5 CBZ24905.1 - 0.25 10.5 6.0 0.58 9.3 0.1 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Carboxyl_trans PF01039.17 CBZ24905.1 - 0.55 8.5 7.9 0.87 7.8 5.5 1.3 1 0 0 1 1 1 0 Carboxyl transferase domain DUF4407 PF14362.1 CBZ24905.1 - 0.74 8.7 12.5 1.2 8.0 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spore_coat_CotO PF14153.1 CBZ24905.1 - 2.9 7.3 15.8 0.081 12.3 5.8 1.9 2 0 0 2 2 2 0 Spore coat protein CotO BSMAP PF12280.3 CBZ24905.1 - 4.4 7.1 10.5 2.1 8.1 3.5 2.4 2 1 0 2 2 2 0 Brain specific membrane anchored protein FUSC PF04632.7 CBZ24905.1 - 9.5 4.5 7.9 14 3.9 5.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Cys_Met_Meta_PP PF01053.15 CBZ24906.1 - 6.2e-115 383.5 0.0 7.6e-115 383.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CBZ24906.1 - 0.00025 19.8 0.1 0.00038 19.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CBZ24906.1 - 0.00087 18.3 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Amastin PF07344.6 CBZ24908.1 - 5.5e-06 26.0 12.4 5.5e-06 26.0 8.6 2.3 1 1 1 2 2 2 1 Amastin surface glycoprotein Vac7 PF12751.2 CBZ24908.1 - 0.16 10.7 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Abhydrolase_9_N PF15420.1 CBZ24908.1 - 0.47 10.1 8.1 0.1 12.3 0.4 2.4 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus PAP2 PF01569.16 CBZ24908.1 - 5.5 6.6 8.3 1.6 8.4 3.3 2.1 1 1 1 2 2 2 0 PAP2 superfamily Amastin PF07344.6 CBZ24909.1 - 5.6e-06 26.0 12.4 5.6e-06 26.0 8.6 2.3 1 1 1 2 2 2 1 Amastin surface glycoprotein Abhydrolase_9_N PF15420.1 CBZ24909.1 - 0.08 12.6 5.3 0.1 12.3 0.4 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus PAP2 PF01569.16 CBZ24909.1 - 2.6 7.7 7.3 1.2 8.7 3.0 2.1 2 1 0 2 2 2 0 PAP2 superfamily FA_desaturase PF00487.19 CBZ24911.1 - 1.4e-16 60.6 22.8 1.4e-16 60.6 15.8 2.3 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 CBZ24911.1 - 7.4e-12 44.9 0.0 1.4e-07 31.1 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Voltage_CLC PF00654.15 CBZ24911.1 - 0.19 10.6 8.0 0.6 9.0 5.5 1.6 1 1 0 1 1 1 0 Voltage gated chloride channel FemAB PF02388.11 CBZ24912.1 - 0.083 11.5 1.8 0.088 11.4 1.2 1.0 1 0 0 1 1 1 0 FemAB family IclR PF01614.13 CBZ24912.1 - 0.084 12.5 1.7 0.11 12.2 1.2 1.1 1 0 0 1 1 1 0 Bacterial transcriptional regulator DUF2336 PF10098.4 CBZ24912.1 - 0.12 11.6 6.8 0.12 11.5 4.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) FANCF PF11107.3 CBZ24912.1 - 0.13 11.5 1.0 0.14 11.3 0.7 1.0 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) LPP20 PF02169.11 CBZ24912.1 - 0.22 11.6 1.3 0.32 11.1 0.9 1.4 1 0 0 1 1 1 0 LPP20 lipoprotein Atg14 PF10186.4 CBZ24912.1 - 0.25 10.2 1.9 0.28 10.0 1.3 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 VlpA_repeat PF04649.7 CBZ24912.1 - 0.29 10.8 1.4 0.58 9.8 0.9 1.4 1 0 0 1 1 1 0 Mycoplasma hyorhinis VlpA repeat Wbp11 PF09429.5 CBZ24912.1 - 5 7.1 8.6 11 6.0 5.9 1.5 1 1 0 1 1 1 0 WW domain binding protein 11 Ion_trans_2 PF07885.11 CBZ24913.1 - 3.5e-09 36.2 6.8 1.1e-08 34.6 4.7 1.8 1 0 0 1 1 1 1 Ion channel DUF2768 PF10966.3 CBZ24913.1 - 0.061 13.4 3.1 2.2 8.5 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Ion_trans_2 PF07885.11 CBZ24914.1 - 3.5e-11 42.6 8.1 3.5e-11 42.6 5.6 2.1 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.21 CBZ24914.1 - 2.9e-05 23.8 1.1 8.5e-05 22.3 0.7 1.7 1 1 0 1 1 1 1 Ligand-gated ion channel Ion_trans PF00520.26 CBZ24914.1 - 0.00026 20.3 13.3 0.0016 17.7 9.2 2.4 1 1 0 1 1 1 1 Ion transport protein FliT PF05400.8 CBZ24914.1 - 0.039 14.3 0.2 0.039 14.3 0.1 2.2 3 0 0 3 3 3 0 Flagellar protein FliT IncA PF04156.9 CBZ24916.1 - 0.0041 16.7 0.2 0.0041 16.7 0.1 1.7 1 1 1 2 2 2 1 IncA protein T2SM PF04612.7 CBZ24916.1 - 0.036 13.8 0.3 0.036 13.8 0.2 1.8 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M WD40 PF00400.27 CBZ24917.1 - 3.2e-29 99.7 21.3 6.5e-06 25.8 0.1 10.7 11 0 0 11 11 11 5 WD domain, G-beta repeat Utp12 PF04003.7 CBZ24917.1 - 1.7e-05 24.6 0.1 3.1e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family BAF1_ABF1 PF04684.8 CBZ24917.1 - 0.013 14.4 0.6 0.025 13.4 0.4 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nup160 PF11715.3 CBZ24917.1 - 0.017 13.3 8.1 0.27 9.3 0.1 2.8 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CBZ24917.1 - 0.046 12.4 0.0 14 4.2 0.0 3.1 3 1 1 4 4 4 0 Nup133 N terminal like Complex1_LYR PF05347.10 CBZ24918.1 - 0.0068 16.1 1.2 0.012 15.3 0.9 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBZ24918.1 - 0.031 14.4 0.2 0.049 13.8 0.2 1.4 1 0 0 1 1 1 0 Complex1_LYR-like YLP PF02757.12 CBZ24918.1 - 0.14 11.8 0.2 0.33 10.7 0.1 1.7 1 0 0 1 1 1 0 YLP motif SpoU_methylase PF00588.14 CBZ24920.1 - 1.9e-09 37.5 0.0 0.0016 18.2 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family Spt5_N PF11942.3 CBZ24921.1 - 0.69 10.5 7.5 0.2 12.3 2.3 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal zf-LSD1 PF06943.7 CBZ24923.1 - 2.8e-07 29.9 9.9 2.8e-07 29.9 6.8 2.6 2 1 0 2 2 2 1 LSD1 zinc finger zinc_ribbon_4 PF13717.1 CBZ24923.1 - 0.017 14.8 0.5 0.017 14.8 0.3 3.4 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBZ24923.1 - 0.017 14.6 0.5 0.017 14.6 0.4 3.3 3 1 1 4 4 4 0 zinc-ribbon domain PHD PF00628.24 CBZ24923.1 - 0.038 13.6 1.1 0.038 13.6 0.8 2.3 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.17 CBZ24923.1 - 3.2 7.5 11.0 4.1 7.2 1.4 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ELO PF01151.13 CBZ24924.1 - 2.1e-34 118.9 12.9 2.6e-34 118.6 9.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MCR_alpha PF02249.12 CBZ24924.1 - 1.4 8.9 5.0 0.34 10.9 0.4 2.2 3 0 0 3 3 3 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain ELO PF01151.13 CBZ24925.1 - 2.7e-65 220.1 10.4 2.7e-65 220.1 7.2 1.6 2 0 0 2 2 2 1 GNS1/SUR4 family ELO PF01151.13 CBZ24926.1 - 1.2e-60 204.9 15.3 1.4e-60 204.7 10.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CBZ24927.1 - 1e-59 201.8 15.8 1.2e-59 201.6 10.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CBZ24929.1 - 2e-67 227.1 5.5 2.3e-67 226.9 3.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Bestrophin PF01062.16 CBZ24929.1 - 0.051 12.5 1.1 0.084 11.8 0.7 1.3 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel ELO PF01151.13 CBZ24930.1 - 1.3e-77 260.5 20.4 1.5e-77 260.2 14.1 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CBZ24931.1 - 2.7e-79 265.9 22.9 3.2e-79 265.7 15.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CBZ24932.1 - 1.2e-75 254.0 19.5 1.4e-75 253.8 13.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Sdh_cyt PF01127.17 CBZ24932.1 - 5.2 6.9 12.9 0.6 9.9 5.7 2.0 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit ELO PF01151.13 CBZ24933.1 - 1e-73 247.7 8.8 1.3e-73 247.4 6.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4199 PF13858.1 CBZ24933.1 - 5.4 6.9 9.4 0.18 11.7 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) ELO PF01151.13 CBZ24934.1 - 1.9e-80 269.7 17.8 2.4e-80 269.4 12.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Vma12 PF11712.3 CBZ24934.1 - 0.15 11.7 2.2 4.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ELO PF01151.13 CBZ24935.1 - 2e-69 233.7 20.9 2.8e-69 233.2 14.5 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CBZ24936.1 - 1.2e-73 247.5 21.9 1.4e-73 247.3 15.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Vma12 PF11712.3 CBZ24936.1 - 0.25 11.0 0.9 0.6 9.8 0.6 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ras PF00071.17 CBZ24938.1 - 9.2e-36 122.6 0.0 1.2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ24938.1 - 1.4e-16 61.0 0.0 2.1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ24938.1 - 1e-08 34.5 0.0 1.5e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ24938.1 - 1.6e-05 24.1 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ24938.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBZ24938.1 - 0.0085 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ24938.1 - 0.021 14.8 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 CBZ24938.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ24938.1 - 0.091 12.3 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3373 PF11853.3 CBZ24938.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) NACHT PF05729.7 CBZ24938.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 CBZ24938.1 - 0.21 11.1 0.0 0.34 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Ribosomal_L21p PF00829.16 CBZ24940.1 - 5.6e-19 68.0 0.0 7.8e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF1682 PF07946.9 CBZ24942.1 - 0.22 10.3 1.8 0.31 9.8 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) PAT1 PF09770.4 CBZ24942.1 - 0.94 7.6 13.1 1.3 7.1 9.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kinesin PF00225.18 CBZ24943.1 - 2e-91 306.2 0.2 3.6e-91 305.3 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain V_ATPase_I PF01496.14 CBZ24943.1 - 4 5.1 2.4 5.7 4.6 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4201 PF13870.1 CBZ24944.1 - 4e-30 104.5 15.9 4e-30 104.5 11.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) KxDL PF10241.4 CBZ24944.1 - 0.0043 16.9 1.5 0.0043 16.9 1.1 3.1 3 1 0 3 3 3 1 Uncharacterized conserved protein DUF948 PF06103.6 CBZ24944.1 - 0.073 12.9 8.5 3.1 7.7 0.1 3.8 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.20 CBZ24945.1 - 4.3e-44 150.6 0.0 2.7e-24 85.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24945.1 - 2.8e-13 49.5 0.0 3.3e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBZ24945.1 - 7.3e-05 22.6 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBZ24945.1 - 0.054 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SNF2_N PF00176.18 CBZ24946.1 - 3.8e-61 206.5 0.0 5.9e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ24946.1 - 6.3e-13 48.4 0.0 2e-12 46.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ24946.1 - 1.1e-06 28.2 0.0 3.3e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CBZ24946.1 - 0.17 10.6 0.0 0.89 8.3 0.0 2.0 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 V_ATPase_I PF01496.14 CBZ24946.1 - 1.1 7.0 2.3 2.1 6.1 1.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1935 PF09149.5 CBZ24947.1 - 1.7e-38 130.7 0.2 1.9e-38 130.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CBZ24948.1 - 1.7e-38 130.7 0.2 1.9e-38 130.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) ATG16 PF08614.6 CBZ24950.1 - 0.32 10.7 1.5 0.9 9.3 1.1 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PP2C PF00481.16 CBZ24952.1 - 6.7e-49 166.5 0.0 3.6e-48 164.1 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ24952.1 - 1.1e-07 31.4 0.1 6.1e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C GSH_synth_ATP PF03917.12 CBZ24953.1 - 2.7e-56 190.7 0.0 2.1e-54 184.5 0.0 3.0 1 1 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CBZ24953.1 - 2e-35 121.0 0.4 5.1e-35 119.7 0.3 1.7 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DNA_pol_A PF00476.15 CBZ24954.1 - 9.3e-28 96.9 0.0 1.5e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A AAA_13 PF13166.1 CBZ24955.1 - 1.9 6.8 6.8 3.8 5.8 4.0 1.8 1 1 0 1 1 1 0 AAA domain Ribosomal_L16 PF00252.13 CBZ24957.1 - 6.9e-23 80.8 0.0 8.8e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PAP_assoc PF03828.14 CBZ24958.1 - 5.4e-16 58.2 0.0 2.9e-11 43.1 0.0 2.8 3 0 0 3 3 3 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBZ24958.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain PRK PF00485.13 CBZ24959.1 - 1.2e-07 31.5 0.0 0.00012 21.7 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 CBZ24959.1 - 4.1e-07 30.3 0.0 0.032 14.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CBZ24959.1 - 0.00066 20.4 0.0 0.0012 19.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ24959.1 - 0.00093 18.9 0.0 0.0032 17.1 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain AAA_25 PF13481.1 CBZ24959.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBZ24959.1 - 0.0029 17.2 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ24959.1 - 0.028 13.5 0.7 0.094 11.8 0.1 2.2 2 1 1 3 3 3 0 Zeta toxin ABC_tran PF00005.22 CBZ24959.1 - 0.03 14.6 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 CBZ24959.1 - 0.033 14.1 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 CBZ24959.1 - 0.037 12.7 0.0 0.059 12.1 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.1 CBZ24959.1 - 0.038 13.8 0.0 0.48 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBZ24959.1 - 0.04 13.4 0.0 0.093 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KTI12 PF08433.5 CBZ24959.1 - 0.042 13.0 0.0 0.084 12.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 CBZ24959.1 - 0.048 13.8 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CBZ24959.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 CBZ24959.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CBZ24959.1 - 0.08 12.9 0.0 0.18 11.7 0.0 1.6 2 0 0 2 2 1 0 50S ribosome-binding GTPase T2SE PF00437.15 CBZ24959.1 - 0.092 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 CBZ24959.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase Na_H_Exchanger PF00999.16 CBZ24960.1 - 1.4e-19 69.9 21.9 2.7e-19 68.9 15.2 1.5 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Mito_carr PF00153.22 CBZ24961.1 - 4.6e-27 93.5 0.0 1.1e-12 47.5 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 CBZ24962.1 - 3.8e-10 39.3 0.2 0.0018 17.9 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF202 PF02656.10 CBZ24966.1 - 2.6e-15 56.3 1.0 4e-14 52.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Abhydrolase_9_N PF15420.1 CBZ24966.1 - 0.095 12.4 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF4293 PF14126.1 CBZ24966.1 - 0.27 11.1 3.9 0.89 9.4 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) COQ9 PF08511.6 CBZ24968.1 - 7.5e-07 28.5 0.0 2.4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 COQ9 Dynein_heavy PF03028.10 CBZ24969.1 - 1.5e-138 462.9 0.0 3.9e-136 454.9 0.0 3.7 2 1 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ24969.1 - 1.9e-120 402.1 0.1 1.9e-120 402.1 0.1 2.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ24969.1 - 5e-95 317.4 0.0 9.2e-95 316.5 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ24969.1 - 9.8e-62 208.3 0.0 2.1e-61 207.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 CBZ24969.1 - 1.5e-44 152.1 4.0 1.5e-44 152.1 2.7 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CBZ24969.1 - 4.9e-42 143.3 0.5 9.7e-42 142.3 0.4 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBZ24969.1 - 1.5e-37 129.1 0.1 5.1e-37 127.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBZ24969.1 - 5.3e-21 74.8 2.1 1.6e-06 27.9 0.0 5.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ24969.1 - 5.3e-06 26.5 10.6 0.0059 16.7 0.0 6.9 6 1 1 7 7 6 1 AAA domain T2SE PF00437.15 CBZ24969.1 - 0.00031 19.7 1.6 0.014 14.2 0.1 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.1 CBZ24969.1 - 0.001 18.5 1.9 1.8 8.1 0.1 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA PF00004.24 CBZ24969.1 - 0.0015 18.7 1.2 2 8.6 0.0 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ24969.1 - 0.019 15.7 0.5 32 5.3 0.0 4.2 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.16 CBZ24969.1 - 0.038 13.1 3.2 3.9 6.5 0.1 4.3 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CBZ24969.1 - 0.14 12.3 0.3 15 5.7 0.0 4.2 4 0 0 4 4 4 0 RNA helicase Pkinase PF00069.20 CBZ24970.1 - 7e-45 153.1 0.0 1.3e-44 152.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24970.1 - 2e-17 63.1 0.0 2.7e-16 59.4 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase PQ-loop PF04193.9 CBZ24972.1 - 2.1e-26 91.2 6.5 3.5e-13 48.8 0.2 2.4 2 0 0 2 2 2 2 PQ loop repeat Kinesin PF00225.18 CBZ24973.1 - 1.7e-102 342.5 0.0 7.1e-102 340.5 0.0 2.3 1 0 0 1 1 1 1 Kinesin motor domain Kinesin PF00225.18 CBZ24974.1 - 2.3e-99 332.2 0.0 2.3e-99 332.2 0.0 2.8 3 0 0 3 3 2 1 Kinesin motor domain Myosin_tail_1 PF01576.14 CBZ24974.1 - 2.4e-48 164.5 345.1 1.8e-16 59.0 35.6 11.0 1 1 7 8 8 6 6 Myosin tail Spc7 PF08317.6 CBZ24974.1 - 3e-19 68.8 268.7 0.0017 17.0 6.0 16.8 1 1 13 17 17 16 13 Spc7 kinetochore protein ATG16 PF08614.6 CBZ24974.1 - 2.3e-15 56.9 322.6 0.033 14.0 4.3 18.8 1 1 19 20 20 18 15 Autophagy protein 16 (ATG16) Flagellin_C PF00700.16 CBZ24974.1 - 2.5e-14 53.1 86.7 9 6.5 0.1 23.4 10 2 21 32 32 32 4 Bacterial flagellin C-terminal helical region CALCOCO1 PF07888.6 CBZ24974.1 - 6.3e-13 47.8 272.5 0.012 13.9 6.5 16.1 1 1 16 17 17 16 14 Calcium binding and coiled-coil domain (CALCOCO1) like E2R135 PF11570.3 CBZ24974.1 - 2.9e-09 37.1 148.2 0.18 11.8 1.1 22.5 3 3 16 23 23 22 15 Coiled-coil receptor-binding R-domain of colicin E2 LigT_PEase PF02834.11 CBZ24974.1 - 2.6e-05 24.1 55.6 2.2 8.2 0.7 11.1 7 2 3 10 10 10 5 LigT like Phosphoesterase GAS PF13851.1 CBZ24974.1 - 0.00022 20.4 313.4 0.051 12.7 6.9 19.9 1 1 22 23 23 20 15 Growth-arrest specific micro-tubule binding APG6 PF04111.7 CBZ24974.1 - 0.00074 18.6 340.0 0.057 12.4 8.2 18.2 1 1 22 23 23 20 12 Autophagy protein Apg6 Reo_sigmaC PF04582.7 CBZ24974.1 - 0.0014 17.9 72.5 0.89 8.6 1.2 13.6 2 2 15 18 18 18 6 Reovirus sigma C capsid protein DUF4047 PF13256.1 CBZ24974.1 - 0.0093 15.9 111.3 0.1 12.5 0.9 14.2 4 4 7 16 16 14 9 Domain of unknown function (DUF4047) Scaffolding_pro PF11418.3 CBZ24974.1 - 2.9 8.2 185.4 3.9 7.8 3.9 29.4 3 3 17 22 22 20 0 Phi29 scaffolding protein DUF3584 PF12128.3 CBZ24974.1 - 3.2 4.9 347.7 0.011 13.1 31.5 9.2 1 1 9 10 10 9 0 Protein of unknown function (DUF3584) Kinesin PF00225.18 CBZ24975.1 - 3.7e-102 341.4 0.0 1e-101 340.0 0.0 1.9 1 0 0 1 1 1 1 Kinesin motor domain Cast PF10174.4 CBZ24975.1 - 1.8e-32 112.3 472.2 3e-12 45.4 88.0 9.1 3 3 4 8 8 8 6 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 CBZ24975.1 - 5.4e-14 52.2 470.8 0.0076 15.8 15.3 18.9 3 3 16 21 21 21 17 IncA protein CENP-F_leu_zip PF10473.4 CBZ24975.1 - 1.1e-06 28.4 497.6 0.71 9.7 8.8 26.1 4 4 20 25 25 25 16 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 CBZ24975.1 - 5.3e-06 24.4 25.8 5.3e-06 24.4 17.9 9.7 3 3 5 9 9 9 7 Myosin tail MscS_porin PF12795.2 CBZ24975.1 - 0.0024 17.2 442.0 0.038 13.3 25.0 14.3 4 3 9 14 14 14 10 Mechanosensitive ion channel porin domain DUF1049 PF06305.6 CBZ24975.1 - 0.022 14.1 7.2 3.2e+02 0.8 0.3 11.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) COG5 PF10392.4 CBZ24975.1 - 2.2 8.2 119.9 15 5.5 1.0 24.6 4 3 33 37 37 37 0 Golgi transport complex subunit 5 WD40 PF00400.27 CBZ24976.1 - 8.7e-05 22.2 8.3 0.0069 16.2 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat CSD PF00313.17 CBZ24977.1 - 1.6e-10 40.6 0.7 2.6e-05 23.9 0.2 3.7 3 0 0 3 3 3 2 'Cold-shock' DNA-binding domain S1-like PF14444.1 CBZ24977.1 - 0.017 14.8 3.1 0.056 13.1 0.0 2.7 3 0 0 3 3 3 0 S1-like Tub PF01167.13 CBZ24978.1 - 5.3e-29 100.9 0.0 4.7e-27 94.5 0.0 2.6 3 0 0 3 3 3 2 Tub family Enolase_C PF00113.17 CBZ24980.1 - 3.5e-129 430.0 0.0 4.7e-129 429.5 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CBZ24980.1 - 6.1e-58 194.4 0.1 1.1e-57 193.5 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CBZ24980.1 - 3.1e-05 23.9 0.0 9.5e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 CBZ24980.1 - 0.0003 19.7 1.1 0.00036 19.5 0.0 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus FYVE PF01363.16 CBZ24981.1 - 6.9e-16 57.9 19.6 2.7e-15 56.0 9.7 3.4 2 1 0 2 2 2 1 FYVE zinc finger Ras PF00071.17 CBZ24981.1 - 3.6e-09 36.2 0.0 5.7e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ24981.1 - 1.8e-05 25.1 0.0 3.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein F-box-like PF12937.2 CBZ24981.1 - 0.0039 16.8 0.1 0.0039 16.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CBZ24981.1 - 0.042 13.5 0.1 0.14 11.8 0.1 1.9 1 0 0 1 1 1 0 F-box domain PAP_central PF04928.12 CBZ24982.1 - 2.9e-81 272.0 0.0 3.9e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CBZ24982.1 - 2.3e-28 98.6 0.0 3.8e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CBZ24982.1 - 0.00074 19.7 0.0 0.0017 18.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 CBZ24982.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm YjeF_N PF03853.10 CBZ24983.1 - 3.4e-47 160.1 0.0 9.6e-47 158.7 0.0 1.8 2 0 0 2 2 2 1 YjeF-related protein N-terminus Carb_kinase PF01256.12 CBZ24983.1 - 7.2e-47 159.7 7.6 1.2e-46 159.0 5.2 1.3 1 0 0 1 1 1 1 Carbohydrate kinase PSS PF03034.10 CBZ24984.1 - 1.8e-109 365.4 13.0 2.6e-109 364.9 9.0 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF4381 PF14316.1 CBZ24984.1 - 0.25 11.4 7.7 4.1 7.5 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) NIF PF03031.13 CBZ24985.1 - 2.2e-15 56.6 0.0 1.4e-06 28.0 0.1 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CBZ24985.1 - 0.0032 17.6 0.1 0.12 12.5 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Reo_sigmaC PF04582.7 CBZ24986.1 - 0.0026 16.9 16.3 0.6 9.2 1.4 4.5 2 1 3 5 5 5 3 Reovirus sigma C capsid protein DUF1635 PF07795.6 CBZ24986.1 - 0.082 12.2 1.9 0.31 10.3 1.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) COG2 PF06148.6 CBZ24986.1 - 3.6 7.4 20.8 0.97 9.3 0.7 5.4 3 2 3 6 6 6 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 CBZ24986.1 - 8.5 6.7 10.8 16 5.8 0.1 5.2 6 0 0 6 6 6 0 Nucleopolyhedrovirus P10 protein Bap31 PF05529.7 CBZ24986.1 - 9.8 5.5 16.1 6.5 6.1 0.3 4.3 4 1 0 4 4 4 0 B-cell receptor-associated protein 31-like HTH_1 PF00126.22 CBZ24987.1 - 0.36 10.6 0.1 0.36 10.6 0.1 3.1 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family FAP PF07174.6 CBZ24988.1 - 4.1 6.6 19.7 0.5 9.6 6.1 2.1 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) Ribosomal_S27 PF01599.14 CBZ24991.1 - 1.5e-20 72.7 3.5 3.1e-20 71.7 2.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CBZ24991.1 - 3.8e-07 29.6 0.0 3.9e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBZ24991.1 - 9.6e-06 24.9 0.0 0.00026 20.3 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin family IBR PF01485.16 CBZ24991.1 - 0.0023 17.7 0.8 0.0037 17.1 0.6 1.4 1 0 0 1 1 1 1 IBR domain F420_oxidored PF03807.12 CBZ24992.1 - 2.5e-06 27.8 0.0 9.6e-06 25.9 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.12 CBZ24992.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Pkinase PF00069.20 CBZ24994.1 - 9.6e-63 211.7 0.0 2.2e-62 210.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ24994.1 - 6.7e-35 120.4 0.0 2.1e-32 112.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBZ24994.1 - 0.058 13.1 0.1 0.54 9.9 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CBZ24994.1 - 0.089 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBZ24994.1 - 0.096 11.6 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SHMT PF00464.14 CBZ24997.1 - 2.4e-173 576.0 0.0 2.8e-173 575.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CBZ24997.1 - 0.033 13.3 0.0 0.081 12.0 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase WD40 PF00400.27 CBZ24997.1 - 0.071 13.0 0.0 0.2 11.5 0.0 1.9 1 1 0 1 1 1 0 WD domain, G-beta repeat DnaJ PF00226.26 CBZ24998.1 - 4.3e-20 71.2 3.7 4.3e-20 71.2 2.6 2.6 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 CBZ24998.1 - 2.2e-11 43.2 10.3 1.4e-05 24.6 0.1 4.8 4 0 0 4 4 4 4 TPR repeat TPR_19 PF14559.1 CBZ24998.1 - 4.4e-10 39.7 22.8 0.012 15.9 1.9 6.0 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ24998.1 - 6.8e-09 36.1 23.9 0.00072 20.1 0.9 5.3 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ24998.1 - 0.00046 20.0 13.2 0.012 15.5 1.2 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ24998.1 - 0.00061 19.2 3.7 0.58 9.8 0.6 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ24998.1 - 0.0021 17.7 1.9 2.9 7.9 0.2 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ24998.1 - 0.0026 17.5 12.9 0.55 10.2 1.4 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ24998.1 - 0.0094 16.5 29.0 3.9 8.3 1.0 8.0 6 3 3 9 9 8 1 Tetratricopeptide repeat Mhr1 PF12829.2 CBZ24998.1 - 0.034 13.9 2.7 1.3 8.9 0.2 3.1 3 0 0 3 3 3 0 Transcriptional regulation of mitochondrial recombination Fis1_TPR_C PF14853.1 CBZ24998.1 - 0.14 12.0 1.7 2.2 8.2 0.1 2.8 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 CBZ24998.1 - 0.18 11.7 18.8 0.36 10.7 0.1 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ24998.1 - 0.24 11.9 14.4 18 6.0 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ24998.1 - 0.69 10.2 6.3 50 4.4 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat GRP PF07172.6 CBZ24998.1 - 3.1 8.3 7.4 6.7 7.2 5.1 1.5 1 0 0 1 1 1 0 Glycine rich protein family FA_desaturase PF00487.19 CBZ24999.1 - 3e-37 128.4 10.8 3e-37 128.4 7.5 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 CBZ24999.1 - 6.5e-05 22.6 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA_17 PF13207.1 CBZ25000.1 - 0.15 12.9 0.0 0.32 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NAD_binding_5 PF07994.7 CBZ25002.1 - 3.2e-115 384.6 0.0 3.7e-115 384.4 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CBZ25002.1 - 1.1e-44 150.7 0.0 1.9e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase tRNA-synt_1b PF00579.20 CBZ25003.1 - 4.7e-54 183.5 0.0 2e-48 165.0 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) EMP24_GP25L PF01105.19 CBZ25005.1 - 1.2e-20 73.9 0.0 1.5e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3142 PF11340.3 CBZ25005.1 - 0.027 14.1 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) LPAM_1 PF08139.7 CBZ25006.1 - 0.087 13.0 0.1 0.087 13.0 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site DUF3784 PF12650.2 CBZ25006.1 - 0.1 12.5 1.4 0.14 12.0 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) Pkinase PF00069.20 CBZ25007.1 - 4.3e-67 225.9 0.0 5.5e-67 225.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25007.1 - 5.6e-45 153.4 0.0 7.6e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25007.1 - 6e-09 35.2 0.1 1.8e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PAT1 PF09770.4 CBZ25007.1 - 1.2 7.2 8.3 1.6 6.8 5.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.27 CBZ25009.1 - 7e-07 28.8 15.2 0.046 13.6 0.0 6.9 8 0 0 8 8 8 3 WD domain, G-beta repeat Reo_sigmaC PF04582.7 CBZ25009.1 - 0.031 13.4 2.2 0.42 9.7 0.4 2.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein C2 PF00168.25 CBZ25010.1 - 0.036 13.8 0.0 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 C2 domain Vac14_Fig4_bd PF11916.3 CBZ25011.1 - 6.3e-53 178.6 1.0 1.4e-52 177.5 0.7 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CBZ25011.1 - 1.1e-08 35.2 0.0 2.1e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CBZ25011.1 - 0.0015 18.4 7.4 0.057 13.5 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat MPC PF03650.8 CBZ25012.1 - 7.3e-11 42.0 0.3 9.7e-11 41.6 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Ten_N PF06484.7 CBZ25013.1 - 0.029 13.4 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Teneurin Intracellular Region GST_N_3 PF13417.1 CBZ25014.1 - 4.7e-08 33.1 0.0 9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 CBZ25014.1 - 1.6e-07 31.2 0.8 4.1e-07 29.8 0.2 1.8 2 0 0 2 2 2 1 Glutaredoxin GST_N_2 PF13409.1 CBZ25014.1 - 0.009 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBZ25014.1 - 0.071 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Syja_N PF02383.13 CBZ25015.1 - 5.8e-19 68.0 0.0 9.6e-19 67.2 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Histone PF00125.19 CBZ25016.1 - 7.3e-14 51.6 0.5 8.8e-14 51.3 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 CBZ25016.1 - 0.0003 20.6 0.1 0.0005 19.9 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 CBZ25016.1 - 0.00044 20.2 0.9 0.00046 20.1 0.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CBZ25016.1 - 0.00061 19.4 0.0 0.00084 19.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CBZ25016.1 - 0.0011 18.7 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 CBZ25016.1 - 0.11 12.3 0.5 0.35 10.7 0.1 2.0 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit GDA1_CD39 PF01150.12 CBZ25018.1 - 1.6e-75 254.2 0.0 3e-75 253.3 0.0 1.3 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CBZ25018.1 - 0.00045 19.4 0.0 0.00066 18.9 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Lysine_decarbox PF03641.9 CBZ25019.1 - 2.6e-24 85.5 0.0 4.9e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase HAD_2 PF13419.1 CBZ25019.1 - 0.072 13.2 0.2 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase NAD_binding_1 PF00175.16 CBZ25020.1 - 2e-26 92.6 0.0 3.2e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBZ25020.1 - 6.5e-24 83.9 0.0 9.5e-24 83.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CBZ25020.1 - 3.5e-07 30.2 0.0 3.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CBZ25020.1 - 0.0035 17.2 0.0 0.006 16.5 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF1191 PF06697.7 CBZ25020.1 - 0.067 11.9 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) MIF4G PF02854.14 CBZ25021.1 - 5.7e-25 87.9 1.2 1.1e-24 87.0 0.9 1.5 1 0 0 1 1 1 1 MIF4G domain CRM1_C PF08767.6 CBZ25021.1 - 0.00031 19.7 0.1 0.0016 17.4 0.0 2.2 2 0 0 2 2 2 1 CRM1 C terminal IMS PF00817.15 CBZ25021.1 - 0.028 14.2 0.1 1 9.1 0.1 2.5 1 1 0 1 1 1 0 impB/mucB/samB family RNA12 PF10443.4 CBZ25022.1 - 0.05 12.0 0.1 0.5 8.8 0.0 2.3 2 1 1 3 3 3 0 RNA12 protein AAA_2 PF07724.9 CBZ25024.1 - 7.6e-40 136.6 1.8 2.8e-31 108.7 0.5 2.7 1 1 1 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 CBZ25024.1 - 1.3e-13 51.2 0.0 5.4e-06 26.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ25024.1 - 7.9e-09 35.3 0.4 2e-05 24.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ25024.1 - 4.1e-06 26.9 0.0 0.00055 20.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBZ25024.1 - 6.1e-06 27.0 0.1 3.1e-05 24.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ25024.1 - 3.4e-05 24.1 0.3 0.00013 22.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain ClpB_D2-small PF10431.4 CBZ25024.1 - 4.1e-05 23.4 0.7 0.00024 20.9 0.0 2.5 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 CBZ25024.1 - 6.9e-05 22.9 0.1 0.00033 20.7 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 CBZ25024.1 - 8.4e-05 21.8 0.1 0.002 17.3 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MCM PF00493.18 CBZ25024.1 - 0.00024 20.0 0.8 0.01 14.6 0.0 2.6 2 1 0 2 2 2 1 MCM2/3/5 family TIP49 PF06068.8 CBZ25024.1 - 0.00041 19.1 0.0 0.0011 17.8 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 CBZ25024.1 - 0.0014 18.3 0.7 0.52 9.9 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.1 CBZ25024.1 - 0.0018 18.1 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 CBZ25024.1 - 0.0022 17.0 0.1 0.019 14.0 0.0 2.3 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 CBZ25024.1 - 0.0034 16.5 0.0 0.0096 15.0 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin DEAD PF00270.24 CBZ25024.1 - 0.004 16.6 0.0 0.36 10.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_33 PF13671.1 CBZ25024.1 - 0.0056 16.5 0.0 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CBZ25024.1 - 0.014 14.7 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 CBZ25024.1 - 0.015 15.2 0.1 0.091 12.7 0.0 2.3 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.21 CBZ25024.1 - 0.017 14.5 0.0 0.053 12.9 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain CPT PF07931.7 CBZ25024.1 - 0.025 14.1 0.2 0.21 11.1 0.0 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 CBZ25024.1 - 0.043 14.1 0.1 0.096 12.9 0.1 1.6 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 CBZ25024.1 - 0.046 12.8 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 UPF0079 PF02367.12 CBZ25024.1 - 0.047 13.3 0.0 0.34 10.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CBZ25024.1 - 0.072 12.7 0.0 2.5 7.7 0.0 2.6 2 1 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.20 CBZ25024.1 - 0.087 12.3 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 CBZ25024.1 - 0.11 12.7 0.0 0.72 10.0 0.0 2.3 2 1 0 2 2 2 0 RNA helicase FMO-like PF00743.14 CBZ25025.1 - 3.9e-27 94.6 0.1 1.5e-22 79.5 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CBZ25025.1 - 4.1e-17 62.9 0.0 1.2e-16 61.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBZ25025.1 - 1.2e-10 41.6 0.0 5.2e-09 36.2 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CBZ25025.1 - 5.3e-09 35.4 0.4 1.3e-06 27.5 0.2 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CBZ25025.1 - 4.7e-05 23.3 0.0 0.00021 21.2 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CBZ25025.1 - 0.00072 19.9 0.1 1.8 8.9 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CBZ25025.1 - 0.00077 19.2 0.2 0.0028 17.4 0.0 2.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding DUF1490 PF07371.7 CBZ25025.1 - 0.0022 17.9 1.7 0.012 15.4 0.1 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1490) IlvN PF07991.7 CBZ25025.1 - 0.0033 16.7 0.0 0.45 9.8 0.0 2.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain HI0933_like PF03486.9 CBZ25025.1 - 0.021 13.3 0.1 0.032 12.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 CBZ25025.1 - 0.022 13.7 0.0 0.042 12.7 0.0 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 CBZ25025.1 - 0.055 12.3 0.3 0.48 9.2 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CBZ25025.1 - 0.087 11.6 1.9 0.15 10.9 0.2 2.3 1 1 0 2 2 2 0 FAD binding domain Acetyltransf_2 PF00797.12 CBZ25026.1 - 0.2 11.2 0.2 0.42 10.1 0.0 1.6 2 0 0 2 2 2 0 N-acetyltransferase Mito_carr PF00153.22 CBZ25027.1 - 3e-44 148.6 0.6 3e-17 62.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 CBZ25028.1 - 1.6e-41 141.5 0.1 3.2e-41 140.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ25028.1 - 3.5e-21 74.8 0.0 1.7e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-CCCH PF00642.19 CBZ25029.1 - 1.7e-05 24.3 6.7 1.7e-05 24.3 4.6 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) oligo_HPY PF08352.7 CBZ25029.1 - 2.3 8.6 10.6 0.46 10.8 0.6 2.8 2 1 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCCH PF00642.19 CBZ25031.1 - 8.6e-05 22.1 4.1 0.00015 21.3 2.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ25031.1 - 0.1 12.6 2.4 0.23 11.5 1.7 1.7 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type PP2C PF00481.16 CBZ25032.1 - 4.1e-63 213.1 0.0 7.4e-63 212.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ25032.1 - 0.00021 20.7 0.1 0.00067 19.1 0.0 1.9 2 1 0 2 2 2 1 Protein phosphatase 2C Pkinase PF00069.20 CBZ25033.1 - 9.5e-47 159.3 0.0 1.5e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25033.1 - 1.4e-14 53.7 0.0 3.3e-14 52.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBZ25033.1 - 0.00028 20.7 0.2 0.0013 18.5 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBZ25033.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CBZ25033.1 - 0.13 11.0 0.1 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PIP49_C PF12260.3 CBZ25033.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Cyt-b5 PF00173.23 CBZ25035.1 - 1.2e-05 24.9 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Adeno_E3_CR2 PF02439.10 CBZ25035.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ribosomal_L13 PF00572.13 CBZ25037.1 - 3.8e-22 78.7 0.7 5.3e-22 78.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 alpha-hel2 PF14456.1 CBZ25037.1 - 0.11 11.2 1.7 0.17 10.6 1.1 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 Metallophos PF00149.23 CBZ25039.1 - 1.5e-29 102.8 0.0 2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 CBZ25041.1 - 1.9e-11 43.3 7.4 7e-06 25.7 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat tRNA-synt_2 PF00152.15 CBZ25042.1 - 3.5e-86 289.0 0.0 5.9e-86 288.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBZ25042.1 - 7.8e-13 48.0 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBZ25042.1 - 1.2e-06 27.9 0.0 0.0093 15.1 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CBZ25042.1 - 0.0024 17.4 0.1 0.11 12.0 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF4404 PF14357.1 CBZ25042.1 - 0.15 12.4 0.8 0.44 10.9 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) FAE1_CUT1_RppA PF08392.7 CBZ25043.1 - 0.059 12.4 0.0 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein RPA_C PF08784.6 CBZ25046.1 - 8.6e-16 58.2 0.4 2.4e-15 56.7 0.3 1.8 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 CBZ25046.1 - 2.4e-08 33.7 0.0 4.1e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain GntR PF00392.16 CBZ25046.1 - 0.081 12.3 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family PPR_2 PF13041.1 CBZ25047.1 - 1.2e-06 28.3 0.2 0.044 13.7 0.0 2.4 2 0 0 2 2 2 2 PPR repeat family RPM2 PF08579.6 CBZ25047.1 - 0.037 14.1 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Prefoldin_2 PF01920.15 CBZ25047.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit PPR_2 PF13041.1 CBZ25048.1 - 1.2e-06 28.3 0.2 0.044 13.7 0.0 2.4 2 0 0 2 2 2 2 PPR repeat family RPM2 PF08579.6 CBZ25048.1 - 0.037 14.1 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Prefoldin_2 PF01920.15 CBZ25048.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Prefoldin subunit Ecotin PF03974.8 CBZ25050.1 - 3.4e-39 133.4 0.0 4e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Ecotin Abhydrolase_3 PF07859.8 CBZ25052.1 - 2.9e-12 46.6 0.0 1e-11 44.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 CBZ25052.1 - 4.1e-11 42.3 0.0 8.6e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 CBZ25052.1 - 6.8e-11 42.1 0.0 1.9e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ25052.1 - 9.3e-08 32.2 0.0 9.3e-08 32.2 0.0 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ25052.1 - 5.8e-06 25.6 1.3 0.0082 15.3 0.1 3.0 3 1 0 3 3 3 2 Prolyl oligopeptidase family DUF4566 PF15130.1 CBZ25052.1 - 0.088 11.9 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) Abhydrolase_3 PF07859.8 CBZ25053.1 - 3.4e-11 43.1 0.0 7.7e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBZ25053.1 - 4.8e-10 39.3 0.0 2.8e-09 36.8 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 CBZ25053.1 - 6.3e-10 38.3 0.0 9.9e-10 37.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 CBZ25053.1 - 1.6e-06 27.5 0.1 0.01 15.0 0.1 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 CBZ25053.1 - 0.029 13.2 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Ribosomal_60s PF00428.14 CBZ25055.1 - 1.6 9.2 5.5 3.9 7.9 3.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PseudoU_synth_2 PF00849.17 CBZ25056.1 - 3.3e-18 66.0 1.4 3.2e-08 33.5 0.2 3.4 3 0 0 3 3 3 3 RNA pseudouridylate synthase DUF3049 PF11250.3 CBZ25056.1 - 1.4 8.7 8.2 0.12 12.1 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3049) Ribosomal_60s PF00428.14 CBZ25057.1 - 1.1e-19 70.6 14.6 1.3e-19 70.3 10.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein 3HBOH PF10605.4 CBZ25057.1 - 0.0091 14.1 6.8 0.0097 14.0 4.7 1.0 1 0 0 1 1 1 1 3HB-oligomer hydrolase (3HBOH) Arg_repressor_C PF02863.13 CBZ25057.1 - 0.019 14.4 0.2 0.019 14.4 0.1 1.8 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain Ribosomal_60s PF00428.14 CBZ25058.1 - 1.1e-19 70.6 14.6 1.3e-19 70.3 10.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein 3HBOH PF10605.4 CBZ25058.1 - 0.0091 14.1 6.8 0.0097 14.0 4.7 1.0 1 0 0 1 1 1 1 3HB-oligomer hydrolase (3HBOH) Arg_repressor_C PF02863.13 CBZ25058.1 - 0.019 14.4 0.2 0.019 14.4 0.1 1.8 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain Asparaginase PF00710.15 CBZ25059.1 - 5.8e-66 222.4 0.0 4.8e-60 203.0 0.0 2.0 2 0 0 2 2 2 2 Asparaginase DUF282 PF03380.9 CBZ25059.1 - 0.0032 17.1 1.0 1.8 8.3 0.0 3.1 3 0 0 3 3 3 2 Caenorhabditis protein of unknown function, DUF282 PPR_2 PF13041.1 CBZ25061.1 - 0.0012 18.7 0.0 0.083 12.8 0.0 2.5 1 1 1 2 2 2 1 PPR repeat family PPR_3 PF13812.1 CBZ25061.1 - 2.9 8.4 7.2 15 6.1 0.0 4.7 5 1 0 5 5 5 0 Pentatricopeptide repeat domain SLBB PF10531.4 CBZ25064.1 - 1e-30 105.4 50.9 28 4.6 0.0 28.4 1 1 25 27 27 27 25 SLBB domain GFO_IDH_MocA PF01408.17 CBZ25064.1 - 7e-13 49.1 29.9 45 4.5 0.0 15.5 8 3 5 15 15 15 1 Oxidoreductase family, NAD-binding Rossmann fold LMP PF04778.7 CBZ25064.1 - 0.00029 20.6 23.2 74 3.0 0.0 12.4 6 5 11 19 19 19 0 LMP repeated region AAA PF00004.24 CBZ25066.1 - 6.6e-39 133.1 0.2 1.4e-38 132.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CBZ25066.1 - 3.5e-06 26.8 0.0 1.2e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 CBZ25066.1 - 6e-06 26.4 0.4 0.0014 18.7 0.0 3.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CBZ25066.1 - 1.2e-05 24.4 0.0 2.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CBZ25066.1 - 1.4e-05 24.8 0.2 0.00012 21.8 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ25066.1 - 0.00021 22.0 1.1 0.00031 21.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CBZ25066.1 - 0.00084 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 CBZ25066.1 - 0.00089 19.2 0.9 0.018 15.0 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 CBZ25066.1 - 0.0013 18.2 0.2 0.084 12.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ25066.1 - 0.0019 17.9 0.0 0.0019 17.9 0.0 3.5 3 1 0 3 3 3 1 Part of AAA domain TIP49 PF06068.8 CBZ25066.1 - 0.0026 16.5 0.0 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 CBZ25066.1 - 0.0027 17.6 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CBZ25066.1 - 0.0049 16.0 0.1 0.011 14.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CBZ25066.1 - 0.026 13.6 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 CBZ25066.1 - 0.026 14.4 2.8 0.034 14.0 0.0 2.7 3 1 0 3 3 3 0 AAA domain DUF815 PF05673.8 CBZ25066.1 - 0.035 13.0 0.0 0.074 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 CBZ25066.1 - 0.043 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CBZ25066.1 - 0.057 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CBZ25066.1 - 0.079 12.6 0.0 0.5 10.0 0.0 2.1 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.17 CBZ25066.1 - 0.095 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 CBZ25066.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 CBZ25066.1 - 0.15 12.3 1.3 0.16 12.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 CBZ25066.1 - 0.29 10.5 0.0 1.5 8.2 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Ecotin PF03974.8 CBZ25068.1 - 1.5e-35 121.6 0.1 2.9e-35 120.7 0.1 1.4 1 0 0 1 1 1 1 Ecotin RasGAP_C PF03836.10 CBZ25072.1 - 0.24 11.0 6.8 0.25 11.0 1.3 2.9 3 0 0 3 3 3 0 RasGAP C-terminus SPC22 PF04573.7 CBZ25074.1 - 6.8e-09 35.2 0.0 3e-06 26.5 0.0 2.9 3 0 0 3 3 3 2 Signal peptidase subunit MDH PF02315.11 CBZ25075.1 - 0.034 14.0 0.1 0.069 13.0 0.1 1.5 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit LLC1 PF14945.1 CBZ25075.1 - 1.1 9.6 4.9 2.2 8.6 0.0 2.5 2 1 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein IncA PF04156.9 CBZ25076.1 - 0.018 14.6 6.6 1.3 8.6 1.0 2.4 2 0 0 2 2 2 0 IncA protein TBPIP PF07106.8 CBZ25076.1 - 6.6 6.2 5.6 1.5 8.2 0.4 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CRAL_TRIO PF00650.15 CBZ25078.1 - 1.6e-16 60.2 0.0 5.1e-15 55.3 0.0 2.6 2 1 0 2 2 2 1 CRAL/TRIO domain DUF842 PF05811.8 CBZ25080.1 - 0.023 14.1 2.0 0.043 13.2 1.4 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) FKBP_N PF01346.13 CBZ25080.1 - 0.69 9.9 3.1 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Kelch_4 PF13418.1 CBZ25081.1 - 2.3e-25 88.1 7.7 1.1e-08 34.6 0.1 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ25081.1 - 1.2e-19 69.7 1.5 0.00027 20.8 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 CBZ25081.1 - 9.4e-18 63.8 14.1 0.00012 22.1 0.0 7.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 CBZ25081.1 - 6.7e-15 54.5 1.5 1.2e-06 28.3 0.1 4.3 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 CBZ25081.1 - 2.2e-12 46.2 4.9 0.00019 21.0 0.0 4.7 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 CBZ25081.1 - 3.5e-09 36.0 4.5 0.0021 17.5 0.1 4.1 4 0 0 4 4 4 2 Kelch motif CDC45 PF02724.9 CBZ25081.1 - 6 4.7 6.8 13 3.6 4.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Ipi1_N PF12333.3 CBZ25084.1 - 5.3e-08 32.7 3.8 3.1e-05 23.8 0.4 3.3 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 CBZ25084.1 - 0.033 14.2 0.7 0.38 10.9 0.1 3.0 2 0 0 2 2 2 0 HEAT repeat V-ATPase_H_C PF11698.3 CBZ25084.1 - 0.077 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 V-ATPase subunit H Arm PF00514.18 CBZ25084.1 - 0.099 12.5 1.8 4.7 7.1 0.3 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Cmc1 PF08583.5 CBZ25085.1 - 0.0024 17.6 1.7 0.0024 17.6 1.2 2.2 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like RseA_C PF03873.8 CBZ25085.1 - 0.018 14.9 0.1 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain UPF0203 PF05254.7 CBZ25085.1 - 0.062 13.1 0.6 0.062 13.1 0.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) tRNA-synt_2c PF01411.14 CBZ25086.1 - 0.0054 15.0 0.0 0.0076 14.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CBZ25086.1 - 0.007 16.2 0.1 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DAO PF01266.19 CBZ25089.1 - 2.5e-06 26.6 0.0 1.7e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CBZ25089.1 - 0.00014 21.0 2.2 1.1 8.2 0.0 3.8 3 1 1 4 4 4 2 FAD binding domain Pyr_redox PF00070.22 CBZ25089.1 - 0.0013 19.1 0.0 0.0028 18.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CBZ25089.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 CBZ25089.1 - 0.16 11.6 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CBZ25089.1 - 0.2 11.2 0.1 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_16 PF10294.4 CBZ25090.1 - 6.4e-09 35.4 0.2 7.7e-06 25.4 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CBZ25090.1 - 5.6e-06 26.9 0.1 9.7e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ25090.1 - 0.058 13.4 0.4 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ25090.1 - 0.087 13.2 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 CBZ25090.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2871 PF11070.3 CBZ25091.1 - 7e-48 162.1 11.3 7.9e-48 161.9 7.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2871) Plant_vir_prot PF01307.12 CBZ25091.1 - 0.042 13.5 0.0 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 Plant viral movement protein Na_Ca_ex PF01699.19 CBZ25091.1 - 0.15 11.6 2.6 0.18 11.4 1.8 1.2 1 0 0 1 1 1 0 Sodium/calcium exchanger protein DUF981 PF06168.6 CBZ25091.1 - 0.16 11.7 4.4 0.067 12.9 1.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF981) TrbC PF04956.8 CBZ25091.1 - 0.18 11.8 2.4 0.41 10.6 1.6 1.7 1 1 0 1 1 1 0 TrbC/VIRB2 family DUF2628 PF10947.3 CBZ25091.1 - 1.4 8.7 4.7 2.6 7.8 3.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) ABC_tran PF00005.22 CBZ25093.1 - 3.2e-54 182.9 0.0 3.5e-29 101.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CBZ25093.1 - 8.7e-39 133.5 61.4 2.9e-26 92.3 19.9 3.6 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 CBZ25093.1 - 2.8e-20 73.4 0.1 1.1e-08 35.3 0.0 4.1 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 CBZ25093.1 - 2.1e-06 27.1 0.0 0.16 11.1 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBZ25093.1 - 1.9e-05 24.0 0.3 0.017 14.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CBZ25093.1 - 0.00042 20.7 0.4 0.054 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CBZ25093.1 - 0.0018 17.5 0.0 0.28 10.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 CBZ25093.1 - 0.0019 17.6 0.1 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain SbcCD_C PF13558.1 CBZ25093.1 - 0.0079 16.0 0.0 2.1 8.3 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF1049 PF06305.6 CBZ25093.1 - 0.032 13.7 3.5 0.12 11.8 2.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Mg_chelatase PF01078.16 CBZ25093.1 - 0.037 13.1 0.4 2.7 7.0 0.0 3.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_15 PF13175.1 CBZ25093.1 - 0.04 12.9 0.0 20 4.0 0.0 3.3 4 0 0 4 4 4 0 AAA ATPase domain Pkinase PF00069.20 CBZ25094.1 - 1.3e-29 103.1 0.0 1.9e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25094.1 - 3.1e-13 49.4 0.0 4.3e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25094.1 - 2.6e-05 23.3 0.0 3.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ25094.1 - 0.034 13.8 0.0 6.4 6.4 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pex16 PF08610.5 CBZ25097.1 - 1.2e-23 83.6 0.3 7.1e-20 71.2 0.0 2.3 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) DPM2 PF07297.7 CBZ25098.1 - 1.9e-17 63.2 1.1 2.6e-17 62.8 0.7 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) GDI PF00996.13 CBZ25099.1 - 1.9e-33 115.4 0.0 1.8e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor Methyltransf_16 PF10294.4 CBZ25099.1 - 3.2e-13 49.5 0.0 5.3e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase MTS PF05175.9 CBZ25099.1 - 0.099 12.0 0.1 0.57 9.5 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 CBZ25099.1 - 0.21 10.6 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DUF566 PF04484.7 CBZ25100.1 - 0.15 11.5 9.4 0.22 10.9 1.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF566) Nuc_sug_transp PF04142.10 CBZ25102.1 - 1.5e-25 89.7 12.6 1.9e-20 72.9 2.6 3.3 2 1 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 CBZ25102.1 - 1.6e-06 28.1 23.9 0.0007 19.6 0.5 3.8 3 1 1 4 4 4 2 EamA-like transporter family TPT PF03151.11 CBZ25102.1 - 0.00051 19.7 17.0 0.067 12.8 4.8 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family Tmemb_18A PF09771.4 CBZ25102.1 - 7.2 6.5 6.9 0.29 11.1 0.2 2.2 3 0 0 3 3 3 0 Transmembrane protein 188 DUF3613 PF12266.3 CBZ25104.1 - 2.7 7.5 9.9 0.065 12.7 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) PAT1 PF09770.4 CBZ25104.1 - 5.8 5.0 8.9 7.7 4.6 6.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MFS_1 PF07690.11 CBZ25105.1 - 4.8e-12 45.2 44.4 5.1e-08 32.0 7.2 3.9 2 2 2 4 4 4 4 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ25105.1 - 2.2e-07 29.8 1.9 2.2e-07 29.8 1.3 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1228 PF06779.9 CBZ25105.1 - 0.014 15.4 4.7 0.076 13.0 1.2 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Inositol_P PF00459.20 CBZ25106.1 - 2.1e-42 145.3 3.0 3.1e-23 82.4 0.4 2.2 2 0 0 2 2 2 2 Inositol monophosphatase family Kdo_hydroxy PF11004.3 CBZ25106.1 - 0.0025 16.8 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase ABC2_membrane PF01061.19 CBZ25107.1 - 8.5e-37 126.3 19.9 1.3e-36 125.7 13.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBZ25107.1 - 1.4e-19 70.7 0.0 2.2e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 CBZ25107.1 - 0.00052 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 CBZ25107.1 - 0.00055 19.9 0.1 0.34 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CBZ25107.1 - 0.0049 16.0 0.0 0.0081 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBZ25107.1 - 0.0052 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CBZ25107.1 - 0.0072 15.8 0.3 0.014 14.8 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 CBZ25107.1 - 0.022 15.0 0.0 0.035 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CBZ25107.1 - 0.032 13.8 0.1 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PRK PF00485.13 CBZ25107.1 - 0.034 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 CBZ25107.1 - 0.034 12.9 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 CBZ25107.1 - 0.054 13.2 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CBZ25107.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 CBZ25107.1 - 0.061 12.9 0.5 0.11 12.0 0.4 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBZ25107.1 - 0.066 13.4 0.0 0.5 10.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 CBZ25107.1 - 0.069 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBZ25107.1 - 0.071 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_15 PF13175.1 CBZ25107.1 - 0.093 11.7 0.0 2.4 7.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_A8 PF01252.13 CBZ25107.1 - 0.094 12.3 3.6 0.2 11.2 2.5 1.5 1 0 0 1 1 1 0 Signal peptidase (SPase) II AAA_25 PF13481.1 CBZ25107.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBZ25107.1 - 0.12 13.2 0.2 0.38 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.14 CBZ25107.1 - 0.13 11.4 0.0 10 5.2 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.14 CBZ25107.1 - 0.15 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CBZ25107.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBZ25107.1 - 0.22 11.8 0.0 0.49 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 CBZ25107.1 - 0.28 10.9 0.2 0.51 10.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_24 PF13479.1 CBZ25107.1 - 0.56 9.7 1.3 1 8.9 0.9 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.2 CBZ25107.1 - 3.9 6.4 20.1 7.8 5.4 14.0 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein HEAT_2 PF13646.1 CBZ25110.1 - 9.7e-22 77.0 14.6 1.8e-09 37.7 0.1 7.5 5 1 3 8 8 8 6 HEAT repeats HEAT PF02985.17 CBZ25110.1 - 9e-21 72.0 22.9 0.0018 18.1 0.0 10.5 10 0 0 10 10 10 8 HEAT repeat Adaptin_N PF01602.15 CBZ25110.1 - 0.00035 19.0 4.9 0.029 12.6 0.1 3.4 2 2 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 CBZ25110.1 - 0.0017 17.7 3.7 0.39 10.0 0.1 4.1 3 2 2 5 5 5 1 CLASP N terminal Cnd1 PF12717.2 CBZ25110.1 - 0.011 15.6 0.6 0.41 10.4 0.0 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.2 CBZ25110.1 - 0.016 14.8 0.1 4.8 6.7 0.0 3.1 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Arm PF00514.18 CBZ25110.1 - 0.032 14.0 3.0 6.6 6.7 0.1 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 CBZ25110.1 - 0.066 13.6 1.5 44 4.5 0.0 5.2 3 2 3 6 6 6 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CBZ25110.1 - 0.096 13.2 24.7 17 6.0 1.8 7.6 8 1 1 9 9 9 0 HEAT-like repeat EF-hand_8 PF13833.1 CBZ25111.1 - 3.6e-09 36.0 0.0 0.0049 16.4 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 CBZ25111.1 - 5.6e-09 35.7 0.0 0.029 14.2 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBZ25111.1 - 8.8e-09 35.3 0.0 2.7e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ25111.1 - 1.7e-05 24.2 0.1 0.78 9.7 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CBZ25111.1 - 0.0002 20.4 0.0 3.4 7.2 0.0 3.4 3 0 0 3 3 3 2 EF hand DUF2087 PF09860.4 CBZ25111.1 - 0.0063 16.2 0.0 0.99 9.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2087) DUF2267 PF10025.4 CBZ25111.1 - 0.017 15.2 0.3 5.2 7.1 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) UBN2 PF14223.1 CBZ25111.1 - 0.037 13.8 0.0 4.5 7.0 0.0 2.3 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type MAP65_ASE1 PF03999.7 CBZ25112.1 - 5e-08 32.0 1.8 5e-08 32.0 1.2 2.4 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Ribosomal_S3_C PF00189.15 CBZ25113.1 - 9.8e-16 57.7 1.0 9.8e-16 57.7 0.7 1.7 2 1 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CBZ25113.1 - 6.2e-09 35.2 0.2 1.5e-08 34.0 0.1 1.6 2 0 0 2 2 2 1 KH domain Evr1_Alr PF04777.8 CBZ25114.1 - 4.8e-24 84.0 0.7 9.8e-24 83.0 0.5 1.5 1 0 0 1 1 1 1 Erv1 / Alr family LINES_C PF14695.1 CBZ25114.1 - 0.13 11.5 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Lines C-terminus ThiF PF00899.16 CBZ25115.1 - 1e-33 116.0 0.0 1.8e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CBZ25115.1 - 7.5e-07 28.6 0.4 2e-06 27.3 0.1 1.9 2 0 0 2 2 2 1 MoeZ/MoeB domain 2-Hacid_dh_C PF02826.14 CBZ25115.1 - 0.0046 16.1 0.0 0.0096 15.0 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CBZ25115.1 - 0.0072 16.4 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 CBZ25115.1 - 0.0092 15.4 0.1 0.033 13.6 0.1 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 CBZ25115.1 - 0.079 12.3 0.1 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rad9 PF04139.8 CBZ25116.1 - 4.6e-09 35.7 0.0 1.9e-06 27.1 0.0 2.3 2 1 0 2 2 2 2 Rad9 Fer4_17 PF13534.1 CBZ25117.1 - 7.3e-08 32.6 0.6 1.5e-07 31.6 0.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CBZ25117.1 - 2.5e-07 30.6 0.8 4.5e-07 29.7 0.6 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBZ25117.1 - 3.9e-06 27.0 0.5 0.0035 17.5 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 CBZ25117.1 - 4.3e-06 27.0 4.7 0.00035 20.9 0.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBZ25117.1 - 0.00012 21.8 0.4 0.00025 20.7 0.3 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CBZ25117.1 - 0.014 15.7 2.9 0.048 14.0 2.0 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 CBZ25117.1 - 0.015 15.6 5.0 0.082 13.2 0.7 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.2 CBZ25117.1 - 3 7.9 6.4 1.2 9.2 0.8 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Ribosomal_L6e PF01159.14 CBZ25118.1 - 8.6e-34 116.0 0.8 3.9e-33 113.9 0.6 1.9 1 1 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.24 CBZ25118.1 - 0.001 18.6 0.0 0.0037 16.9 0.0 1.9 1 1 1 2 2 2 1 KOW motif ELFV_dehydrog PF00208.16 CBZ25119.1 - 1.5e-44 152.4 0.0 2.6e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CBZ25119.1 - 2.4e-19 68.4 0.0 1.2e-10 39.5 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase polyprenyl_synt PF00348.12 CBZ25120.1 - 3.4e-50 170.3 0.0 5e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase SQS_PSY PF00494.14 CBZ25120.1 - 0.012 14.8 0.2 0.036 13.3 0.2 1.8 1 1 0 1 1 1 0 Squalene/phytoene synthase DUF3609 PF12259.3 CBZ25120.1 - 0.1 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) SKIP_SNW PF02731.10 CBZ25121.1 - 1.2e-07 31.3 3.0 1.2e-07 31.3 2.1 3.0 2 1 1 3 3 3 1 SKIP/SNW domain AhpC-TSA PF00578.16 CBZ25122.1 - 5.3e-36 123.0 0.0 6.7e-36 122.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBZ25122.1 - 1.8e-16 59.9 0.0 2.1e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBZ25122.1 - 5e-14 51.6 0.0 1.1e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.16 CBZ25125.1 - 1.3e-37 128.1 0.0 1.7e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBZ25125.1 - 8.9e-18 64.2 0.0 1.1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBZ25125.1 - 5e-14 51.6 0.0 1.1e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin TF_Zn_Ribbon PF08271.7 CBZ25126.1 - 1.5e-05 24.2 1.0 2.6e-05 23.4 0.7 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding DUF2387 PF09526.5 CBZ25126.1 - 0.051 13.5 0.8 0.11 12.3 0.5 1.5 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) cNMP_binding PF00027.24 CBZ25128.1 - 7.2e-10 38.5 0.0 1.7e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pkinase PF00069.20 CBZ25129.1 - 9.5e-56 188.8 0.0 1.6e-55 188.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25129.1 - 1.5e-40 138.8 0.0 2.7e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 CBZ25129.1 - 1.7e-27 95.0 0.4 2.5e-13 49.6 0.1 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain PAS PF00989.19 CBZ25129.1 - 2e-07 30.7 0.0 7.5e-07 28.9 0.0 2.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 CBZ25129.1 - 4.8e-07 30.1 0.0 2.3e-06 27.8 0.0 2.3 1 0 0 1 1 1 1 PAS domain Kinase-like PF14531.1 CBZ25129.1 - 5.9e-07 28.7 0.0 4.2e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CBZ25129.1 - 0.22 10.8 0.0 0.49 9.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Ribosomal_60s PF00428.14 CBZ25130.1 - 1.5e-22 79.7 12.4 1.9e-22 79.4 8.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_60s PF00428.14 CBZ25131.1 - 1.5e-22 79.7 12.4 1.9e-22 79.4 8.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Exo_endo_phos PF03372.18 CBZ25132.1 - 5.5e-20 72.3 0.0 1.4e-19 70.9 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 CBZ25132.1 - 7.5e-12 45.1 0.0 1.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain DnaJ PF00226.26 CBZ25133.1 - 8.3e-26 89.5 1.8 1.3e-25 88.8 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CBZ25133.1 - 9.7e-10 38.3 11.9 1.8e-09 37.5 8.3 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 CBZ25133.1 - 9.1e-07 28.6 0.0 0.0039 17.0 0.0 3.5 2 1 0 2 2 2 2 DnaJ C terminal domain Nucleoside_tran PF01733.13 CBZ25134.1 - 1e-34 120.1 14.1 3.6e-34 118.3 6.2 2.9 2 1 0 2 2 2 2 Nucleoside transporter Nucleoside_tran PF01733.13 CBZ25135.1 - 2e-34 119.1 12.6 8.2e-34 117.1 5.7 2.8 2 1 0 2 2 2 2 Nucleoside transporter UFC1 PF08694.6 CBZ25136.1 - 2.2e-81 271.0 0.1 2.5e-81 270.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.21 CBZ25136.1 - 0.0007 19.0 0.5 0.00095 18.6 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBZ25136.1 - 0.023 14.5 0.4 0.038 13.8 0.3 1.4 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 CBZ25136.1 - 0.047 13.4 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B DUF2510 PF10708.4 CBZ25136.1 - 0.87 9.0 4.6 19 4.7 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) SET PF00856.23 CBZ25137.1 - 7.1e-08 32.9 0.2 3.1e-07 30.8 0.0 2.1 3 0 0 3 3 3 1 SET domain DUF433 PF04255.9 CBZ25137.1 - 0.13 11.6 0.6 20 4.6 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF433) DNA_topoisoIV PF00521.15 CBZ25140.1 - 1.3e-105 353.7 0.0 2.2e-105 352.9 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CBZ25140.1 - 3e-12 46.0 0.0 9e-12 44.5 0.0 1.8 1 1 1 2 2 2 1 DNA gyrase B Toprim PF01751.17 CBZ25140.1 - 1.8e-11 43.9 0.0 5.3e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CBZ25140.1 - 2.4e-07 30.4 0.0 5.5e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBZ25140.1 - 0.00011 21.8 0.1 0.00031 20.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAB PF04382.8 CBZ25140.1 - 0.018 14.7 0.1 0.05 13.2 0.1 1.7 1 0 0 1 1 1 0 SAB domain DUF3045 PF11243.3 CBZ25140.1 - 0.064 13.4 0.3 0.2 11.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3045) UCH PF00443.24 CBZ25141.1 - 5.1e-36 124.1 0.0 8.2e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ25141.1 - 6.9e-13 48.6 0.0 1.4e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 CBZ25141.1 - 4.3e-12 45.8 0.0 9.1e-05 21.8 0.0 3.1 2 1 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 CBS PF00571.23 CBZ25141.1 - 0.34 10.7 1.2 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 CBS domain CorA PF01544.13 CBZ25142.1 - 5.4e-25 88.0 8.9 2.7e-22 79.1 1.2 2.5 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein SHOCT PF09851.4 CBZ25142.1 - 3e-05 23.3 0.0 5.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Short C-terminal domain Macoilin PF09726.4 CBZ25142.1 - 0.0032 15.8 4.4 0.0039 15.5 3.0 1.2 1 0 0 1 1 1 1 Transmembrane protein DMAP_binding PF06464.6 CBZ25142.1 - 0.71 10.4 10.2 2.3 8.8 6.5 2.4 2 1 0 2 2 2 0 DMAP1-binding Domain MIF4G PF02854.14 CBZ25143.1 - 2.9e-10 39.9 0.0 6.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain Actin PF00022.14 CBZ25144.1 - 2.7e-100 335.5 0.0 3.1e-100 335.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBZ25144.1 - 0.0092 14.6 0.0 0.13 10.8 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein EF-hand_7 PF13499.1 CBZ25145.1 - 0.1 12.7 0.1 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair NIF PF03031.13 CBZ25146.1 - 0.084 12.5 0.0 0.84 9.2 0.0 2.2 2 1 0 2 2 2 0 NLI interacting factor-like phosphatase RabGAP-TBC PF00566.13 CBZ25148.1 - 4.3e-06 26.3 0.4 8.2e-06 25.4 0.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain 2OG-FeII_Oxy PF03171.15 CBZ25149.1 - 1.8e-10 40.9 0.0 4.3e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily KCl_Cotrans_1 PF03522.10 CBZ25149.1 - 1.3 8.5 2.9 4.1 6.9 0.4 2.2 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) Actin PF00022.14 CBZ25150.1 - 1.1e-73 247.9 0.0 1.5e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBZ25150.1 - 9.5e-09 34.2 0.0 3.1e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein Stomoxyn PF11585.3 CBZ25150.1 - 3.1 7.6 6.9 4.7 7.1 0.1 3.1 3 0 0 3 3 3 0 Insect antimicrobial peptide, stomoxyn DUF1796 PF08795.5 CBZ25151.1 - 4.4e-49 166.3 0.0 9.1e-49 165.2 0.0 1.5 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Nop PF01798.13 CBZ25152.1 - 1.6e-53 180.0 0.8 1.6e-53 180.0 0.5 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 CBZ25152.1 - 1.3e-26 92.1 0.0 2.5e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CBZ25152.1 - 4.2e-05 23.6 1.0 0.13 12.4 0.1 2.7 1 1 1 2 2 2 2 NOP5NT (NUC127) domain DUF3306 PF11748.3 CBZ25152.1 - 0.18 12.4 1.9 0.57 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) TMEM164 PF14808.1 CBZ25153.1 - 1.8e-09 37.1 3.0 2.4e-09 36.7 2.1 1.2 1 0 0 1 1 1 1 TMEM164 family EBV-NA3 PF05009.7 CBZ25154.1 - 0.055 12.7 0.5 0.087 12.0 0.3 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Whib PF02467.11 CBZ25154.1 - 0.062 13.6 1.0 0.42 10.9 0.1 2.4 2 0 0 2 2 2 0 Transcription factor WhiB Alkyl_sulf_dimr PF14863.1 CBZ25154.1 - 0.082 13.1 0.1 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation End3 PF12761.2 CBZ25154.1 - 0.11 12.0 1.2 0.17 11.5 0.8 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF3568 PF12092.3 CBZ25154.1 - 0.22 11.2 1.1 0.37 10.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) zf-RING_2 PF13639.1 CBZ25155.1 - 8.3e-13 47.9 8.6 1.8e-12 46.8 5.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ25155.1 - 6.5e-08 32.4 8.0 1.2e-07 31.6 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ25155.1 - 4.2e-07 29.9 5.4 1e-06 28.7 3.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBZ25155.1 - 1.8e-06 27.4 5.4 3.4e-06 26.6 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ25155.1 - 0.00015 21.4 5.6 0.00027 20.6 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBZ25155.1 - 0.00015 21.3 6.1 0.00028 20.4 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBZ25155.1 - 0.00042 19.9 3.1 0.00089 18.9 2.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 CBZ25155.1 - 0.013 15.4 7.3 0.29 11.1 5.1 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 CBZ25155.1 - 0.021 14.6 4.6 0.051 13.4 3.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CBZ25155.1 - 0.19 11.3 6.8 0.4 10.3 4.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MutS_V PF00488.16 CBZ25156.1 - 1.5e-57 194.7 0.0 4e-57 193.3 0.0 1.6 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CBZ25156.1 - 1.5e-27 96.7 0.1 2.3e-27 96.1 0.1 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CBZ25156.1 - 9.5e-19 67.4 0.0 1.6e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 CBZ25156.1 - 0.00027 21.0 0.0 0.00047 20.2 0.0 1.3 1 0 0 1 1 1 1 MutS family domain IV tRNA-synt_1c PF00749.16 CBZ25158.1 - 6.3e-100 333.8 0.0 8.3e-100 333.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CBZ25158.1 - 1.5e-40 138.7 0.0 2.3e-40 138.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PCNA_N PF00705.13 CBZ25159.1 - 1.1e-41 141.2 1.5 1.7e-41 140.6 0.7 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CBZ25159.1 - 5.4e-38 129.8 0.1 1.2e-19 70.5 0.1 2.3 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 CBZ25159.1 - 5.6e-08 32.2 0.0 7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 CBZ25159.1 - 7.5e-05 21.6 0.2 0.0016 17.2 0.1 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 CBZ25159.1 - 0.0031 16.5 0.0 0.12 11.3 0.0 2.2 2 0 0 2 2 2 1 Hus1-like protein GHMP_kinases_N PF00288.21 CBZ25160.1 - 1.9e-12 47.0 0.7 6.9e-12 45.2 0.5 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBZ25160.1 - 6.1e-06 26.3 0.3 0.00012 22.1 0.1 2.5 2 0 0 2 2 2 1 GHMP kinases C terminal ICE2 PF08426.5 CBZ25161.1 - 0.054 12.1 0.0 0.067 11.7 0.0 1.1 1 0 0 1 1 1 0 ICE2 Ribosomal_L7Ae PF01248.21 CBZ25162.1 - 5.7e-25 86.6 0.1 6.7e-25 86.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 CBZ25162.1 - 0.00052 19.7 0.0 0.00072 19.2 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.6 CBZ25162.1 - 0.0012 18.7 0.2 0.0013 18.6 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PDEase_I PF00233.14 CBZ25163.1 - 6.9e-60 202.7 0.1 1.6e-59 201.5 0.0 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 CBZ25163.1 - 3.2e-41 140.9 0.2 2.3e-20 73.3 0.0 3.4 3 1 0 3 3 3 2 GAF domain GAF_3 PF13492.1 CBZ25163.1 - 1.1e-20 74.0 0.2 5.4e-10 39.4 0.0 3.5 3 0 0 3 3 3 3 GAF domain GAF_2 PF13185.1 CBZ25163.1 - 3.7e-18 66.4 0.0 1.8e-06 28.4 0.0 3.5 3 0 0 3 3 3 3 GAF domain PDEase_I PF00233.14 CBZ25164.1 - 2.9e-60 203.9 0.4 6e-60 202.9 0.0 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.21 CBZ25164.1 - 7.9e-40 136.4 0.0 1.8e-19 70.3 0.0 2.6 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.1 CBZ25164.1 - 4e-18 65.7 0.1 6.8e-09 35.9 0.0 3.5 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.1 CBZ25164.1 - 8.5e-15 55.5 0.1 7e-06 26.5 0.0 3.3 3 0 0 3 3 3 2 GAF domain DUF58 PF01882.13 CBZ25164.1 - 0.029 14.4 0.8 4.5 7.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function DUF58 Sld5 PF05916.6 CBZ25167.1 - 0.027 14.7 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 GINS complex protein Presenilin PF01080.12 CBZ25169.1 - 1.9e-51 175.1 32.2 6.5e-37 127.3 12.9 2.0 1 1 1 2 2 2 2 Presenilin Wyosine_form PF08608.7 CBZ25170.1 - 2.7e-19 69.0 0.0 7.2e-19 67.6 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.16 CBZ25170.1 - 9.9e-18 64.8 0.0 1.6e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Pkinase PF00069.20 CBZ25172.1 - 1.4e-59 201.4 0.0 1.6e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25172.1 - 9.3e-27 93.7 0.0 6.7e-26 90.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.16 CBZ25172.1 - 2.1e-15 56.3 3.8 5.1e-15 55.1 2.6 1.7 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.18 CBZ25172.1 - 0.00026 20.8 0.1 0.0018 18.0 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FYVE_2 PF02318.11 CBZ25172.1 - 0.00049 19.9 2.7 0.00049 19.9 1.9 2.0 2 0 0 2 2 2 1 FYVE-type zinc finger Kinase-like PF14531.1 CBZ25172.1 - 0.0077 15.2 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 CBZ25172.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cnd1 PF12717.2 CBZ25173.1 - 2.7e-40 138.1 2.7 1.4e-34 119.5 0.0 4.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CBZ25173.1 - 3.3e-05 23.5 5.2 5.1 7.4 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat Cnd1_N PF12922.2 CBZ25173.1 - 0.0026 17.3 0.0 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_EZ PF13513.1 CBZ25173.1 - 0.012 16.0 0.1 33 5.1 0.0 4.5 3 0 0 3 3 3 0 HEAT-like repeat PAT1 PF09770.4 CBZ25174.1 - 1.2 7.2 7.3 4 5.5 5.1 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 zf-C2H2_4 PF13894.1 CBZ25174.1 - 3.3 8.2 5.7 2.7 8.5 1.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger ASF1_hist_chap PF04729.8 CBZ25175.1 - 8.1e-32 109.9 0.0 9.6e-32 109.7 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone Ribosomal_L18e PF00828.14 CBZ25176.1 - 0.039 14.3 0.0 0.083 13.2 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L18e/L15 ADK PF00406.17 CBZ25177.1 - 1.2e-10 41.4 0.2 1.2e-05 25.1 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.1 CBZ25177.1 - 1e-08 36.0 0.1 4.4e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ25177.1 - 9.9e-07 28.7 0.2 8e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ25177.1 - 3.2e-05 23.0 0.2 6.6e-05 22.0 0.1 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBZ25177.1 - 4.4e-05 23.1 0.3 9.4e-05 22.0 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 CBZ25177.1 - 6.7e-05 22.9 0.3 0.00039 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ25177.1 - 0.00021 21.3 0.0 0.00031 20.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CBZ25177.1 - 0.00033 20.9 0.1 0.00091 19.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ25177.1 - 0.0013 18.8 0.0 0.0036 17.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CBZ25177.1 - 0.0017 18.0 0.0 0.0055 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CBZ25177.1 - 0.0031 17.1 0.4 0.0093 15.5 0.1 1.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 CBZ25177.1 - 0.0043 16.5 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CBZ25177.1 - 0.0068 15.8 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBZ25177.1 - 0.0074 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Thymidylate_kin PF02223.12 CBZ25177.1 - 0.0091 15.3 0.1 2.7 7.3 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase AAA PF00004.24 CBZ25177.1 - 0.0091 16.1 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 CBZ25177.1 - 0.01 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 CBZ25177.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 CBZ25177.1 - 0.013 15.2 0.2 0.028 14.1 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 CBZ25177.1 - 0.014 14.6 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_10 PF12846.2 CBZ25177.1 - 0.015 14.7 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 CBZ25177.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit T2SE PF00437.15 CBZ25177.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 CBZ25177.1 - 0.021 13.8 0.0 0.09 11.8 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 CBZ25177.1 - 0.029 13.8 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 CBZ25177.1 - 0.03 14.2 0.1 0.087 12.7 0.0 1.7 1 1 1 2 2 2 0 AAA domain Guanylate_kin PF00625.16 CBZ25177.1 - 0.033 13.6 0.0 2.6 7.4 0.0 2.2 1 1 1 2 2 2 0 Guanylate kinase UPF0079 PF02367.12 CBZ25177.1 - 0.034 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 CBZ25177.1 - 0.04 13.4 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 CBZ25177.1 - 0.042 13.8 0.0 0.08 12.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 CBZ25177.1 - 0.043 13.4 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CBZ25177.1 - 0.058 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 CBZ25177.1 - 0.059 12.8 0.1 0.15 11.5 0.1 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.10 CBZ25177.1 - 0.061 13.1 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GTP_EFTU PF00009.22 CBZ25177.1 - 0.076 12.4 0.1 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Mg_chelatase PF01078.16 CBZ25177.1 - 0.085 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.12 CBZ25177.1 - 0.094 12.2 0.4 0.17 11.4 0.1 1.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CobU PF02283.11 CBZ25177.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase PrmA PF06325.8 CBZ25178.1 - 1.1e-05 24.6 0.1 1.7e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CBZ25178.1 - 0.00066 19.6 0.1 0.0011 19.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ25178.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CBZ25178.1 - 0.0038 17.7 0.0 0.0067 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBZ25178.1 - 0.075 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase 2OG-FeII_Oxy_3 PF13640.1 CBZ25179.1 - 2.6e-12 47.1 0.1 6e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 CBZ25179.1 - 1e-07 31.4 0.4 3e-07 29.9 0.3 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 CBZ25179.1 - 8.6e-05 22.6 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy PF03171.15 CBZ25179.1 - 0.043 14.1 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 CBZ25179.1 - 0.047 12.4 0.0 0.12 11.1 0.0 1.7 1 1 0 1 1 1 0 Poxvirus C4/C10 protein TPR_6 PF13174.1 CBZ25179.1 - 0.093 13.2 0.1 0.31 11.5 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DEAD PF00270.24 CBZ25180.1 - 1.5e-16 60.3 0.0 1.9e-14 53.4 0.0 2.3 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ25180.1 - 3.4e-15 55.6 0.0 1.1e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1491 PF07372.7 CBZ25180.1 - 0.019 14.8 0.1 0.06 13.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) ResIII PF04851.10 CBZ25180.1 - 0.049 13.4 0.0 0.16 11.7 0.0 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBZ25180.1 - 0.07 13.2 0.1 8.7 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CBZ25181.1 - 1.9e-45 154.2 0.0 4.4e-45 153.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBZ25181.1 - 1.2e-06 27.7 0.0 2.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBZ25181.1 - 0.00018 21.5 0.0 0.00038 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBZ25181.1 - 0.00039 20.4 2.8 0.011 15.7 0.0 3.6 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 CBZ25181.1 - 0.00051 20.1 0.0 0.018 15.1 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 CBZ25181.1 - 0.00052 19.7 0.0 0.0019 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ25181.1 - 0.00062 20.5 0.0 0.0019 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ25181.1 - 0.00093 19.1 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Vps4_C PF09336.5 CBZ25181.1 - 0.00095 19.0 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_33 PF13671.1 CBZ25181.1 - 0.0025 17.6 0.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 CBZ25181.1 - 0.0026 16.6 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 CBZ25181.1 - 0.0039 16.3 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 CBZ25181.1 - 0.0043 17.2 0.0 0.0097 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 CBZ25181.1 - 0.0043 16.4 0.0 0.0094 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBZ25181.1 - 0.017 14.2 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CBZ25181.1 - 0.018 13.7 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus ABC_tran PF00005.22 CBZ25181.1 - 0.021 15.1 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 CBZ25181.1 - 0.024 14.0 0.2 0.17 11.3 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA_28 PF13521.1 CBZ25181.1 - 0.03 14.2 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CBZ25181.1 - 0.042 13.0 0.1 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 CBZ25181.1 - 0.051 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC SKI PF01202.17 CBZ25181.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.1 CBZ25181.1 - 0.1 12.1 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 CBZ25181.1 - 0.13 11.0 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 CBZ25181.1 - 0.24 11.6 0.0 0.47 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Kelch_4 PF13418.1 CBZ25183.1 - 1.9e-34 117.1 0.5 1.8e-08 34.0 0.0 6.8 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 CBZ25183.1 - 2.5e-32 110.2 3.3 4.6e-08 32.9 0.0 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ25183.1 - 2.7e-28 97.4 1.4 0.00048 20.0 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBZ25183.1 - 3.2e-23 80.8 3.9 9.1e-05 22.4 0.0 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 CBZ25183.1 - 4.5e-21 74.1 0.0 3.2e-06 26.5 0.0 5.4 5 0 0 5 5 5 4 Kelch motif DUF4110 PF13422.1 CBZ25183.1 - 8.6e-21 73.5 12.5 8.6e-21 73.5 8.7 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.10 CBZ25183.1 - 6.1e-16 57.4 2.7 0.0032 17.1 0.0 6.3 6 0 0 6 6 6 4 Kelch motif MORN PF02493.15 CBZ25185.1 - 3.1e-13 48.5 8.1 3e-08 32.8 0.6 4.6 4 0 0 4 4 4 2 MORN repeat APH PF01636.18 CBZ25186.1 - 2.9e-13 50.1 0.0 6.7e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family eIF-1a PF01176.14 CBZ25190.1 - 3.5e-18 64.7 0.4 4.9e-18 64.2 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 YL1 PF05764.8 CBZ25190.1 - 0.17 11.5 3.4 0.28 10.7 2.3 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Ribosomal_L17 PF01196.14 CBZ25192.1 - 6.4e-15 55.5 0.1 9.3e-15 54.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 CD52 PF15116.1 CBZ25194.1 - 0.064 13.0 0.9 0.15 11.8 0.3 1.9 2 0 0 2 2 2 0 CAMPATH-1 antigen Las1 PF04031.8 CBZ25195.1 - 8.3e-41 139.2 0.0 1.2e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Las1-like Mito_carr PF00153.22 CBZ25196.1 - 2.2e-63 210.0 0.5 4.3e-21 74.4 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 CBZ25197.1 - 3.2e-53 177.4 4.2 4.7e-19 67.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DSPc PF00782.15 CBZ25199.1 - 6.5e-08 32.2 0.0 7.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ25199.1 - 9.8e-06 25.0 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Radical_SAM PF04055.16 CBZ25200.1 - 8.9e-14 51.9 0.0 3e-13 50.2 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CBZ25200.1 - 1.7e-08 34.3 0.2 1.8e-07 31.0 0.1 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CBZ25200.1 - 0.053 13.6 0.2 0.18 11.9 0.1 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPc PF00782.15 CBZ25201.1 - 1.2e-08 34.5 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ25201.1 - 1.6e-06 27.6 0.0 4.2e-06 26.2 0.0 1.5 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Abhydrolase_5 PF12695.2 CBZ25202.1 - 1e-25 90.2 0.0 1.5e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ25202.1 - 4.9e-18 65.8 0.0 8.5e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_5 PF13857.1 CBZ25202.1 - 3.6e-11 42.9 0.1 9.7e-09 35.2 0.0 2.9 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBZ25202.1 - 1.8e-09 37.7 0.1 1.3e-07 31.8 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ25202.1 - 6.5e-08 32.8 1.0 7.8e-05 23.0 0.1 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ25202.1 - 1.6e-07 30.8 0.1 1e-05 25.2 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Peptidase_S9 PF00326.16 CBZ25202.1 - 9.9e-07 28.1 0.2 4e-05 22.9 0.1 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family Ank PF00023.25 CBZ25202.1 - 6.1e-06 25.7 0.1 0.00012 21.7 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat AXE1 PF05448.7 CBZ25202.1 - 6.7e-05 21.5 0.6 0.22 9.9 0.2 2.3 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 CBZ25202.1 - 0.00084 19.1 0.6 0.0029 17.4 0.1 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 CBZ25202.1 - 0.00086 18.9 0.3 0.37 10.3 0.2 2.5 2 1 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CBZ25202.1 - 0.013 14.9 0.0 0.075 12.4 0.0 2.0 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2424 PF10340.4 CBZ25202.1 - 0.017 13.7 0.0 3.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) BAAT_C PF08840.6 CBZ25202.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF3447 PF11929.3 CBZ25202.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) Abhydro_lipase PF04083.11 CBZ25202.1 - 0.11 11.8 0.0 15 4.9 0.0 2.4 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ins145_P3_rec PF08709.6 CBZ25204.1 - 1.9e-38 131.6 0.0 6.3e-36 123.4 0.0 3.2 2 1 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.6 CBZ25204.1 - 4.1e-23 81.1 0.2 4.1e-23 81.1 0.2 2.4 2 0 0 2 2 2 1 RyR and IP3R Homology associated Rhabdo_M1 PF03342.8 CBZ25204.1 - 0.081 12.0 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) MIR PF02815.14 CBZ25204.1 - 0.089 12.3 0.1 0.82 9.1 0.0 2.1 2 0 0 2 2 2 0 MIR domain Ion_trans PF00520.26 CBZ25204.1 - 0.18 11.0 12.3 0.54 9.4 8.5 1.9 1 0 0 1 1 1 0 Ion transport protein GRASP55_65 PF04495.9 CBZ25205.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.7 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 CBZ25205.1 - 0.042 13.7 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DUF1266 PF06889.6 CBZ25205.1 - 0.063 13.0 1.3 0.098 12.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) PDZ PF00595.19 CBZ25205.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Herpes_UL25 PF01499.11 CBZ25205.1 - 1.9 6.7 11.8 1.1e+02 0.8 8.2 2.0 1 1 0 1 1 1 0 Herpesvirus UL25 family Pkinase PF00069.20 CBZ25206.1 - 1.2e-67 227.7 0.0 1.6e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25206.1 - 1e-48 165.7 0.0 1.3e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25206.1 - 0.0016 17.4 0.0 0.0035 16.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like CT47 PF15623.1 CBZ25206.1 - 0.006 16.3 3.1 0.014 15.1 2.1 1.6 1 0 0 1 1 1 1 Cancer/testis gene family 47 FMN_bind PF04205.9 CBZ25206.1 - 1.2 9.3 5.1 4 7.6 0.9 2.6 1 1 1 2 2 2 0 FMN-binding domain Met_10 PF02475.11 CBZ25207.1 - 5.2e-48 163.3 0.0 5.5e-35 120.7 0.0 2.2 2 0 0 2 2 2 2 Met-10+ like-protein PrmA PF06325.8 CBZ25207.1 - 0.0012 17.9 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.11 CBZ25207.1 - 0.054 12.4 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase FHA PF00498.21 CBZ25208.1 - 7.7e-14 51.5 0.0 2.5e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 FHA domain DUF1073 PF06381.6 CBZ25209.1 - 0.068 11.6 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1073) Oxidored_q6 PF01058.17 CBZ25209.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit EBP PF05241.7 CBZ25210.1 - 2.1e-29 101.9 3.4 2.5e-29 101.6 2.4 1.1 1 0 0 1 1 1 1 Emopamil binding protein 2OG-FeII_Oxy_2 PF13532.1 CBZ25211.1 - 5.8e-54 182.8 0.1 7.5e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IncA PF04156.9 CBZ25213.1 - 0.0023 17.5 0.2 0.0033 17.0 0.2 1.2 1 0 0 1 1 1 1 IncA protein Beta_helix PF13229.1 CBZ25213.1 - 0.035 13.8 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 Right handed beta helix region NosD PF05048.8 CBZ25213.1 - 0.04 13.0 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) End3 PF12761.2 CBZ25213.1 - 0.13 11.9 0.9 0.2 11.3 0.6 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DivIVA PF05103.8 CBZ25213.1 - 0.16 12.0 1.2 0.26 11.3 0.8 1.3 1 0 0 1 1 1 0 DivIVA protein FlaC_arch PF05377.6 CBZ25213.1 - 0.23 11.3 0.2 0.42 10.5 0.2 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) TTL PF03133.10 CBZ25214.1 - 2.6e-76 256.3 0.0 1.7e-75 253.7 0.0 2.1 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ25214.1 - 0.00037 19.3 0.0 0.16 10.7 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 CBZ25214.1 - 0.0039 16.9 0.0 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_ST PF14397.1 CBZ25214.1 - 0.018 14.1 0.0 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp XRN_N PF03159.13 CBZ25215.1 - 8.7e-18 64.5 0.3 6.2e-13 48.6 0.1 3.3 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus Pyridoxal_deC PF00282.14 CBZ25218.1 - 2e-20 72.5 0.1 7.9e-14 50.8 0.0 2.3 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain GHMP_kinases_N PF00288.21 CBZ25220.1 - 5.2e-07 29.6 0.3 3.3e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBZ25220.1 - 0.00081 19.5 0.1 0.004 17.3 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal Fucokinase PF07959.7 CBZ25221.1 - 3.6e-22 78.5 0.0 3.1e-20 72.1 0.0 2.1 1 1 1 2 2 2 2 L-fucokinase Ribosomal_L21e PF01157.13 CBZ25223.1 - 1.9e-35 120.6 2.9 2.8e-35 120.1 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Ribosomal_S10 PF00338.17 CBZ25223.1 - 0.13 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e Amastin PF07344.6 CBZ25224.1 - 8.2e-06 25.5 11.7 1.1e-05 25.0 8.1 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein Cation_efflux PF01545.16 CBZ25224.1 - 0.092 11.8 7.8 0.075 12.0 1.0 2.2 1 1 1 2 2 2 0 Cation efflux family MR_MLE_C PF13378.1 CBZ25224.1 - 0.19 11.7 2.1 0.3 11.0 1.5 1.3 1 0 0 1 1 1 0 Enolase C-terminal domain-like VIT1 PF01988.14 CBZ25224.1 - 0.21 11.0 6.3 0.051 13.0 2.1 1.9 1 1 1 2 2 2 0 VIT family TMEM192 PF14802.1 CBZ25224.1 - 0.28 10.0 7.5 0.27 10.0 4.5 1.6 1 1 1 2 2 2 0 TMEM192 family Fucokinase PF07959.7 CBZ25225.1 - 2.3e-28 98.9 0.0 2.1e-19 69.4 0.0 3.1 2 1 0 2 2 2 2 L-fucokinase GHMP_kinases_N PF00288.21 CBZ25225.1 - 3e-06 27.2 0.8 1e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBZ25225.1 - 0.003 17.7 0.0 0.014 15.5 0.0 2.2 1 0 0 1 1 1 1 GHMP kinases C terminal Amastin PF07344.6 CBZ25227.1 - 0.00062 19.3 15.2 0.00062 19.3 10.6 2.3 2 1 0 2 2 2 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ25227.1 - 0.28 10.8 20.4 0.014 15.1 9.9 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3481 PF11980.3 CBZ25227.1 - 1.5 8.6 0.0 1.5 8.6 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3481) RLL PF10036.4 CBZ25229.1 - 0.056 12.8 0.1 0.096 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative carnitine deficiency-associated protein Iso_dh PF00180.15 CBZ25229.1 - 0.12 11.3 1.5 1.4 7.8 0.1 2.1 2 0 0 2 2 2 0 Isocitrate/isopropylmalate dehydrogenase DHO_dh PF01180.16 CBZ25230.1 - 4.1e-68 229.5 0.0 4.6e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase PcrB PF01884.12 CBZ25230.1 - 0.023 13.9 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 PcrB family FMN_dh PF01070.13 CBZ25230.1 - 0.068 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase F_bP_aldolase PF01116.15 CBZ25230.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II OTCace_N PF02729.16 CBZ25231.1 - 1.2e-41 141.7 0.2 1.7e-41 141.2 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 CBZ25231.1 - 1.4e-36 125.7 0.2 7.1e-35 120.2 0.0 2.1 2 0 0 2 2 2 2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OMPdecase PF00215.19 CBZ25232.1 - 7.2e-38 130.2 0.0 1.1e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 CBZ25232.1 - 2.9e-18 65.7 2.1 1.4e-17 63.5 1.5 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 CBZ25232.1 - 0.00018 20.8 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase UPRTase PF14681.1 CBZ25232.1 - 0.001 18.3 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Whirly PF08536.6 CBZ25232.1 - 0.091 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Whirly transcription factor AAA_17 PF13207.1 CBZ25233.1 - 0.00029 21.6 0.0 0.0012 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ25233.1 - 0.015 15.6 0.0 0.045 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 CBZ25233.1 - 0.038 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Histone PF00125.19 CBZ25234.1 - 8e-27 93.1 0.6 8e-27 93.1 0.4 2.1 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ25234.1 - 1.3e-05 25.1 0.2 1.3e-05 25.1 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CBZ25234.1 - 2.1e-05 24.5 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 CBZ25234.1 - 0.0097 15.6 0.1 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 CBZ25235.1 - 8e-27 93.1 0.6 8e-27 93.1 0.4 2.1 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ25235.1 - 1.3e-05 25.1 0.2 1.3e-05 25.1 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CBZ25235.1 - 2.1e-05 24.5 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 CBZ25235.1 - 0.0097 15.6 0.1 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Amidohydro_4 PF13147.1 CBZ25236.1 - 9.5e-21 75.0 8.9 3.2e-20 73.3 6.2 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CBZ25236.1 - 0.00027 20.6 0.1 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CBZ25236.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase Amidohydro_2 PF04909.9 CBZ25236.1 - 0.033 13.7 0.3 2.8 7.4 0.2 2.3 2 1 0 2 2 2 0 Amidohydrolase DHOase PF12890.2 CBZ25236.1 - 0.11 12.1 0.0 0.81 9.3 0.0 2.1 1 1 0 1 1 1 0 Dihydro-orotase-like CPSase_L_D2 PF02786.12 CBZ25237.1 - 9.1e-102 338.7 0.3 1.6e-76 256.2 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CBZ25237.1 - 1.7e-44 150.4 0.0 3.9e-44 149.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CBZ25237.1 - 6.6e-43 146.4 0.0 1.6e-42 145.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ATP-grasp_4 PF13535.1 CBZ25237.1 - 1.2e-35 122.9 1.2 9.1e-22 77.6 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 CBZ25237.1 - 2.1e-35 121.1 0.0 7.5e-20 71.0 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 CBZ25237.1 - 2.8e-35 120.7 0.0 5.5e-35 119.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.17 CBZ25237.1 - 3.2e-21 75.4 0.3 5e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBZ25237.1 - 3.9e-21 75.1 0.0 7.6e-16 57.7 0.0 3.4 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Arginosuc_synth PF00764.14 CBZ25237.1 - 3.7e-13 49.2 0.0 1e-12 47.8 0.0 1.7 1 0 0 1 1 1 1 Arginosuccinate synthase MGS PF02142.17 CBZ25237.1 - 2.1e-12 46.8 0.0 9.5e-12 44.7 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 CBZ25237.1 - 9.7e-12 44.7 0.4 6.9e-06 25.5 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus Peptidase_C26 PF07722.8 CBZ25237.1 - 1.8e-07 30.8 0.1 6.9e-06 25.6 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 CBZ25237.1 - 9.9e-06 25.5 0.2 0.00065 19.6 0.0 2.7 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 CBZ25237.1 - 3.1e-05 23.6 0.3 0.12 11.9 0.0 3.2 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.13 CBZ25237.1 - 0.0098 15.8 0.0 0.078 12.9 0.0 2.6 3 0 0 3 3 2 1 TrkA-N domain GSH-S_ATP PF02955.11 CBZ25237.1 - 0.019 14.0 0.0 0.053 12.6 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DJ-1_PfpI PF01965.19 CBZ25237.1 - 0.039 13.4 0.0 0.095 12.1 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Histone PF00125.19 CBZ25238.1 - 8e-27 93.1 0.6 8e-27 93.1 0.4 2.1 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ25238.1 - 1.3e-05 25.1 0.2 1.3e-05 25.1 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CBZ25238.1 - 2.1e-05 24.5 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 CBZ25238.1 - 0.0097 15.6 0.1 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 CBZ25239.1 - 8e-27 93.1 0.6 8e-27 93.1 0.4 2.1 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ25239.1 - 1.3e-05 25.1 0.2 1.3e-05 25.1 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 CBZ25239.1 - 2.1e-05 24.5 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 CBZ25239.1 - 0.0097 15.6 0.1 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TP6A_N PF04406.9 CBZ25241.1 - 1.1e-11 44.2 0.9 2.5e-11 43.0 0.6 1.7 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.5 CBZ25241.1 - 0.0091 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) RRM_1 PF00076.17 CBZ25242.1 - 1.7e-13 49.9 0.0 3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ25242.1 - 2.3e-08 33.9 0.0 4.2e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ25242.1 - 3.2e-08 33.2 0.1 5.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 CBZ25242.1 - 4.8e-07 30.1 0.0 0.035 14.3 0.0 2.4 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-rbx1 PF12678.2 CBZ25243.1 - 1.1e-17 63.8 7.0 1.4e-17 63.5 4.9 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBZ25243.1 - 8.2e-15 54.4 7.3 1e-14 54.1 5.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBZ25243.1 - 5.5e-09 35.7 17.3 1.1e-07 31.5 12.2 2.1 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CBZ25243.1 - 4.4e-06 26.3 13.4 2.9e-05 23.7 6.4 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBZ25243.1 - 7.1e-05 22.7 13.6 0.0064 16.5 9.4 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ25243.1 - 9.5e-05 21.9 14.1 0.0039 16.8 6.4 2.5 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBZ25243.1 - 0.0001 22.0 5.1 0.0001 22.0 3.5 1.9 1 1 1 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 CBZ25243.1 - 0.0036 16.9 13.2 0.017 14.7 9.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CBZ25243.1 - 0.01 15.7 13.7 0.032 14.2 2.7 3.1 1 1 2 3 3 3 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 CBZ25243.1 - 0.022 14.4 11.0 0.2 11.3 7.4 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-Di19 PF05605.7 CBZ25243.1 - 0.084 13.0 9.9 0.24 11.5 3.5 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 CBZ25243.1 - 0.086 12.4 9.7 2.7 7.6 4.8 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Tax PF02959.11 CBZ25243.1 - 0.3 10.5 3.5 0.42 10.0 2.4 1.2 1 0 0 1 1 1 0 HTLV Tax DUF2162 PF09930.4 CBZ25243.1 - 0.44 9.6 2.4 0.52 9.4 1.6 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) zf-Nse PF11789.3 CBZ25243.1 - 0.63 9.6 7.2 1.9 8.0 5.0 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF1272 PF06906.6 CBZ25243.1 - 0.88 9.4 10.4 25 4.8 7.2 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) C1_1 PF00130.17 CBZ25243.1 - 1.1 9.0 11.4 0.69 9.6 6.1 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rad50_zn_hook PF04423.9 CBZ25243.1 - 3 7.3 5.1 30 4.1 0.1 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.1 CBZ25243.1 - 6.2 6.7 14.0 16 5.4 1.6 3.5 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING DUF948 PF06103.6 CBZ25244.1 - 2.8 7.8 22.0 1.8 8.4 0.2 5.7 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 CBZ25244.1 - 4.5 6.3 26.2 0.34 10.0 3.1 3.7 1 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF1738 PF08401.6 CBZ25245.1 - 2e-05 24.3 0.1 0.014 15.0 0.0 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF1738) Exo_endo_phos PF03372.18 CBZ25246.1 - 2.8e-24 86.4 0.1 3.7e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pap_E4 PF02711.9 CBZ25246.1 - 0.88 10.4 4.4 1.7 9.5 3.0 1.5 1 0 0 1 1 1 0 E4 protein Mucin PF01456.12 CBZ25246.1 - 5.5 6.7 18.7 13 5.4 13.0 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein eIF2A PF08662.6 CBZ25247.1 - 7.1e-38 130.2 0.0 2.3e-34 118.8 0.0 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A LysM PF01476.15 CBZ25248.1 - 3.2e-08 33.3 0.0 0.00028 20.7 0.0 2.6 2 0 0 2 2 2 2 LysM domain LRR_6 PF13516.1 CBZ25250.1 - 3.8e-10 38.7 12.4 0.027 14.4 0.2 6.5 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 CBZ25250.1 - 1.9e-06 27.3 7.1 0.0027 17.2 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ25250.1 - 4.5e-05 22.9 10.4 8.5 6.8 0.1 5.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_8 PF13855.1 CBZ25250.1 - 0.00021 20.9 4.1 0.031 14.0 0.1 4.1 4 0 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 CBZ25250.1 - 1.7 9.1 15.8 25 5.6 0.1 5.8 5 0 0 5 5 5 0 Leucine rich repeat UCH PF00443.24 CBZ25251.1 - 9.8e-40 136.3 0.0 1.5e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ25251.1 - 8e-21 74.7 0.0 3.5e-20 72.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.13 CBZ25251.1 - 0.0039 16.2 1.1 0.0039 16.2 0.8 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Transaldolase PF00923.14 CBZ25254.1 - 1.2e-95 319.9 0.1 1.3e-95 319.7 0.1 1.0 1 0 0 1 1 1 1 Transaldolase Pirin PF02678.11 CBZ25254.1 - 0.031 14.1 0.2 0.082 12.7 0.0 1.8 2 0 0 2 2 2 0 Pirin SH3BGR PF04908.10 CBZ25255.1 - 0.0014 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Chorein_N PF12624.2 CBZ25256.1 - 1.3e-16 60.2 0.1 6e-10 38.6 0.1 2.6 2 0 0 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CBZ25256.1 - 9.9e-07 28.2 0.0 0.19 10.9 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF1162) Glyco_hydro_18 PF00704.23 CBZ25257.1 - 3.8e-55 187.6 0.0 4.8e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mem_trans PF03547.13 CBZ25258.1 - 3.4e-14 51.9 18.0 1.1e-11 43.6 0.0 3.6 4 1 0 4 4 4 2 Membrane transport protein Methyltransf_18 PF12847.2 CBZ25259.1 - 0.014 16.0 0.0 0.037 14.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain EF-hand_1 PF00036.27 CBZ25260.1 - 0.073 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 EF hand Fe-S_biosyn PF01521.15 CBZ25261.1 - 5.7e-08 32.6 0.0 2.7e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis JAB PF01398.16 CBZ25263.1 - 3.4e-19 68.6 0.0 5.8e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CBZ25263.1 - 0.00083 18.8 0.0 0.002 17.6 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.20 CBZ25265.1 - 5.7e-35 120.7 0.0 1e-34 119.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25265.1 - 8.9e-25 87.2 0.0 1.5e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-H2C2_5 PF13909.1 CBZ25265.1 - 0.055 13.7 2.1 0.13 12.5 1.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Nop52 PF05997.7 CBZ25267.1 - 6.7e-44 149.9 0.3 5e-37 127.4 0.1 3.4 3 0 0 3 3 3 3 Nucleolar protein,Nop52 EF-hand_1 PF00036.27 CBZ25270.1 - 1.1e-10 39.9 1.9 5.1e-05 22.2 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBZ25270.1 - 1.2e-09 37.2 0.4 0.00057 19.5 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 CBZ25270.1 - 1.1e-08 35.0 0.1 3.9e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBZ25270.1 - 1.4e-06 27.3 0.6 3e-05 23.1 0.0 3.1 2 1 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBZ25270.1 - 1.6e-05 24.4 5.7 5e-05 22.8 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBZ25270.1 - 0.0084 16.1 0.0 0.017 15.1 0.0 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 PF13499.1 CBZ25271.1 - 4.2e-12 46.0 0.2 6.1e-08 32.6 0.0 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ25271.1 - 7.6e-12 44.0 2.1 0.00081 19.0 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 CBZ25271.1 - 1.3e-10 39.8 4.3 7.2e-05 21.8 0.0 4.4 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 CBZ25271.1 - 5.9e-06 25.8 5.6 7.5e-05 22.2 0.0 3.7 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 CBZ25271.1 - 4.2e-05 22.6 0.1 4.2e-05 22.6 0.0 3.5 4 1 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 CBZ25271.1 - 0.0057 16.6 0.2 0.02 14.8 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Snf7 PF03357.16 CBZ25272.1 - 3.8e-26 91.4 8.3 3.8e-26 91.4 5.8 1.5 2 0 0 2 2 2 1 Snf7 DUF3801 PF12687.2 CBZ25272.1 - 0.0001 21.9 1.8 0.0001 21.9 1.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3801) IFT46_B_C PF12317.3 CBZ25272.1 - 0.73 9.1 4.8 3 7.1 1.1 2.2 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Dynein_light PF01221.13 CBZ25273.1 - 1.4e-26 92.2 0.6 1.6e-26 92.0 0.4 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 YsaB PF13983.1 CBZ25273.1 - 0.092 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 YsaB-like lipoprotein Glycos_transf_1 PF00534.15 CBZ25274.1 - 1.8e-28 99.1 0.0 2.9e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBZ25274.1 - 3.2e-13 50.0 0.0 7.1e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBZ25274.1 - 0.00051 20.2 0.0 0.0015 18.7 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Methyltransf_11 PF08241.7 CBZ25275.1 - 5.6e-15 55.6 0.0 2.5e-13 50.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ25275.1 - 3.2e-13 49.6 0.0 3e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ25275.1 - 9.6e-12 44.5 0.0 1.4e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CBZ25275.1 - 1.1e-06 28.3 0.0 0.00012 21.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ25275.1 - 6.6e-06 26.5 0.0 0.0012 19.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ25275.1 - 0.0093 16.3 0.0 0.083 13.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ25275.1 - 0.049 14.2 0.2 0.38 11.3 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Reo_sigmaC PF04582.7 CBZ25277.1 - 0.005 16.0 36.1 0.038 13.1 0.7 5.9 1 1 5 7 7 7 6 Reovirus sigma C capsid protein Pkinase PF00069.20 CBZ25278.1 - 1.4e-59 201.3 0.0 2e-58 197.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25278.1 - 1.9e-28 99.2 0.0 3.3e-19 68.9 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25278.1 - 0.053 12.4 0.0 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DUF3184 PF11380.3 CBZ25279.1 - 0 1113.5 32.5 1.2e-168 562.1 15.8 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CBZ25280.1 - 0 1070.9 33.8 7.3e-166 553.0 1.5 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CBZ25282.1 - 0 1110.2 32.3 1.6e-167 558.5 16.1 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CBZ25283.1 - 0 1064.0 29.9 1.3e-164 548.8 0.2 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3184) DUF1275 PF06912.6 CBZ25283.1 - 0.04 13.1 0.1 0.077 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DUF3184 PF11380.3 CBZ25284.1 - 0 1221.2 2.3 0 1220.9 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3184) GCFC PF07842.7 CBZ25284.1 - 0.25 10.6 0.4 0.5 9.6 0.0 1.6 2 0 0 2 2 2 0 GC-rich sequence DNA-binding factor-like protein DUF3184 PF11380.3 CBZ25285.1 - 0 1150.4 2.4 0 1150.1 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3184) Ufm1 PF03671.9 CBZ25286.1 - 5.3e-27 93.3 0.1 6.6e-27 93.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Polyketide_cyc PF03364.15 CBZ25290.1 - 0.01 15.8 0.7 0.01 15.8 0.5 2.0 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 CBZ25291.1 - 7.1e-12 45.4 2.8 5.3e-11 42.6 1.9 2.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 CBZ25292.1 - 8.9e-10 38.6 2.5 7e-09 35.7 1.7 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport tRNA_bind PF01588.15 CBZ25294.1 - 7.8e-23 80.1 0.0 1.5e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain WW PF00397.21 CBZ25295.1 - 4e-44 148.0 41.2 4.7e-13 48.7 1.2 5.9 6 0 0 6 6 6 4 WW domain Toxin_57 PF15535.1 CBZ25295.1 - 0.079 13.0 9.5 13 5.8 0.0 4.6 4 1 1 5 5 5 0 Putative toxin 57 Mcp5_PH PF12814.2 CBZ25295.1 - 0.17 11.8 0.8 34 4.3 0.0 3.4 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology Tbf5 PF06331.7 CBZ25296.1 - 0.14 11.9 0.0 1.4 8.7 0.0 2.0 1 1 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 DUF763 PF05559.6 CBZ25297.1 - 0.27 10.1 2.2 0.48 9.3 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Ribosomal_L39 PF00832.15 CBZ25299.1 - 2.3e-19 68.5 14.3 2.6e-19 68.3 9.9 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Methyltransf_FA PF12248.3 CBZ25299.1 - 0.081 12.9 0.0 0.089 12.8 0.0 1.1 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase Adap_comp_sub PF00928.16 CBZ25300.1 - 5.9e-13 48.5 0.0 9.2e-13 47.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBZ25300.1 - 0.00026 20.7 0.1 0.00048 19.8 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF221 PF02714.10 CBZ25301.1 - 1.9e-30 105.8 8.5 3.6e-30 104.9 5.9 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF4590 PF15257.1 CBZ25301.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) DUF3675 PF12428.3 CBZ25301.1 - 0.14 12.3 2.9 0.14 12.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Pro_isomerase PF00160.16 CBZ25302.1 - 1.8e-30 106.1 0.0 2.7e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD dsrm PF00035.20 CBZ25303.1 - 0.00026 21.5 0.1 3.7 8.1 0.0 4.3 4 0 0 4 4 4 2 Double-stranded RNA binding motif Cullin PF00888.17 CBZ25304.1 - 7.3e-32 110.6 0.0 4.3e-18 65.1 0.0 4.5 5 0 0 5 5 5 4 Cullin family Cullin_Nedd8 PF10557.4 CBZ25304.1 - 7.5e-19 67.3 0.0 1.3e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain LSM PF01423.17 CBZ25307.1 - 0.00015 21.2 0.0 0.00035 20.0 0.0 1.7 1 1 0 1 1 1 1 LSM domain CIA30 PF08547.7 CBZ25310.1 - 0.09 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) DAGK_acc PF00609.14 CBZ25311.1 - 8.9e-21 74.6 0.0 3.4e-20 72.8 0.0 1.9 1 1 1 2 2 2 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CBZ25311.1 - 9.6e-07 28.2 0.0 4.2e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cytochrom_C PF00034.16 CBZ25313.1 - 1.3e-09 38.7 0.0 1.7e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CBZ25313.1 - 1.2e-05 25.4 0.7 8.3e-05 22.6 0.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CBZ25314.1 - 1.3e-09 38.7 0.0 1.7e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CBZ25314.1 - 1.2e-05 25.4 0.7 8.3e-05 22.6 0.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III LRR_4 PF12799.2 CBZ25315.1 - 1.8e-28 97.6 26.7 4.3e-05 23.0 0.5 12.2 10 2 4 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ25315.1 - 3.2e-09 36.4 35.7 0.00076 19.1 2.1 8.8 7 2 1 8 8 8 4 Leucine rich repeat LRR_6 PF13516.1 CBZ25315.1 - 9.5e-09 34.4 30.9 19 5.7 0.0 14.8 13 3 3 16 16 16 1 Leucine Rich repeat LRR_9 PF14580.1 CBZ25315.1 - 0.0017 17.9 15.0 0.42 10.1 0.2 4.7 3 2 1 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.28 CBZ25315.1 - 1.3 9.3 30.1 24 5.5 0.1 11.2 12 1 0 12 12 12 0 Leucine Rich Repeat Crl PF07417.7 CBZ25316.1 - 0.4 10.4 0.0 0.86 9.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Crl RNA_pol_Rpb1_5 PF04998.12 CBZ25317.1 - 2.5e-61 207.3 0.0 5.1e-61 206.3 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CBZ25317.1 - 4.8e-46 156.7 0.0 8.5e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CBZ25317.1 - 8.3e-31 106.8 0.0 1.8e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CBZ25317.1 - 1.2e-14 53.9 0.3 3.5e-14 52.4 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF2786 PF10979.3 CBZ25317.1 - 0.84 9.3 9.7 3 7.6 1.8 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) Amidase PF01425.16 CBZ25318.1 - 1.1e-56 192.5 0.0 4.9e-56 190.4 0.0 1.8 1 1 0 1 1 1 1 Amidase LSM PF01423.17 CBZ25319.1 - 0.00064 19.2 0.0 0.00082 18.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain Arf PF00025.16 CBZ25320.1 - 1.4e-47 161.1 0.0 1.6e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ25320.1 - 3.3e-10 39.7 0.2 2.9e-08 33.3 0.0 2.0 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBZ25320.1 - 3.6e-10 39.3 0.0 4.6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBZ25320.1 - 1.2e-08 34.9 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CBZ25320.1 - 2.2e-08 33.6 0.0 2.6e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBZ25320.1 - 1.6e-07 30.4 1.6 0.00049 18.9 0.2 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBZ25320.1 - 1.6e-06 27.4 0.1 2e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBZ25320.1 - 2.5e-06 27.9 0.0 3.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 CBZ25320.1 - 0.00085 18.6 0.4 0.0026 17.0 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 CBZ25320.1 - 0.0053 16.9 0.0 0.046 13.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 CBZ25320.1 - 0.019 14.3 0.0 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 CBZ25320.1 - 0.025 14.4 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 CBZ25320.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.12 CBZ25320.1 - 0.15 11.6 0.4 1.5 8.2 0.1 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein OTU PF02338.14 CBZ25321.1 - 2.9e-15 56.9 0.0 5.4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CBZ25321.1 - 0.041 13.2 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase C65 Otubain EMG1 PF03587.9 CBZ25322.1 - 7.4e-75 250.6 0.0 9e-75 250.4 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase TRAPP PF04051.11 CBZ25323.1 - 7.4e-29 100.2 0.0 9.4e-29 99.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.5 CBZ25323.1 - 0.09 12.5 0.1 0.7 9.7 0.0 2.2 1 1 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) IFP_35_N PF07334.8 CBZ25324.1 - 0.051 13.5 1.5 0.19 11.6 1.1 2.0 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4407 PF14362.1 CBZ25324.1 - 0.15 10.9 19.0 0.29 10.0 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3140 PF11338.3 CBZ25324.1 - 0.3 11.2 0.0 0.3 11.2 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3140) FlxA PF14282.1 CBZ25324.1 - 3 7.8 12.5 0.68 9.9 2.7 2.8 1 1 1 2 2 2 0 FlxA-like protein RloB PF13707.1 CBZ25325.1 - 0.0077 15.8 0.6 0.014 15.0 0.4 1.4 1 0 0 1 1 1 1 RloB-like protein PucR PF07905.6 CBZ25325.1 - 0.081 12.5 0.1 4 7.0 0.0 2.3 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family Flagellar_rod PF05149.7 CBZ25326.1 - 3.3e-61 207.0 5.2 4.5e-61 206.5 3.6 1.2 1 0 0 1 1 1 1 Paraflagellar rod protein Apolipoprotein PF01442.13 CBZ25326.1 - 0.011 15.2 2.2 0.011 15.2 1.5 3.0 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain DDE_Tnp_1 PF01609.16 CBZ25326.1 - 0.034 13.6 0.4 0.034 13.6 0.3 1.4 2 0 0 2 2 2 0 Transposase DDE domain Med30 PF11315.3 CBZ25326.1 - 0.62 10.1 6.3 0.16 12.1 0.8 2.0 2 0 0 2 2 2 0 Mediator complex subunit 30 Flagellar_rod PF05149.7 CBZ25327.1 - 3.8e-112 374.2 24.7 3.8e-112 374.2 17.1 2.1 2 0 0 2 2 2 1 Paraflagellar rod protein DUF1136 PF06582.7 CBZ25327.1 - 0.21 11.3 2.8 0.31 10.7 0.5 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF1136) OsmC PF02566.14 CBZ25327.1 - 5.3 7.2 7.2 2.4 8.4 0.3 3.5 3 1 0 3 3 3 0 OsmC-like protein PAPS_reduct PF01507.14 CBZ25327.1 - 8.2 6.2 10.6 8.6 6.1 2.1 3.1 2 1 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Kinesin PF00225.18 CBZ25330.1 - 2.8e-81 272.8 0.0 1.3e-78 264.0 0.0 3.6 2 0 0 2 2 2 1 Kinesin motor domain Laminin_I PF06008.9 CBZ25330.1 - 4.1e-53 180.3 466.4 0.0017 17.7 12.5 24.8 3 2 24 28 28 26 25 Laminin Domain I Spc7 PF08317.6 CBZ25330.1 - 5.6e-22 77.8 428.4 0.016 13.8 16.5 17.9 2 2 19 21 21 21 16 Spc7 kinetochore protein Laminin_II PF06009.7 CBZ25330.1 - 2.6e-19 69.3 389.8 0.75 9.5 9.0 28.0 5 1 30 35 35 33 26 Laminin Domain II DUF3552 PF12072.3 CBZ25330.1 - 1.9e-16 59.8 457.9 0.92 8.6 9.9 29.6 1 1 30 34 34 32 14 Domain of unknown function (DUF3552) Tropomyosin PF00261.15 CBZ25330.1 - 1.8e-15 56.7 534.6 0.004 16.2 35.0 14.1 2 2 8 12 12 10 8 Tropomyosin Reo_sigmaC PF04582.7 CBZ25330.1 - 9e-13 48.1 311.3 1.3 8.1 6.3 20.2 3 2 18 24 24 24 18 Reovirus sigma C capsid protein COG2 PF06148.6 CBZ25330.1 - 5.5e-11 42.4 287.7 5.5 6.8 0.5 31.6 3 2 39 43 43 43 14 COG (conserved oligomeric Golgi) complex component, COG2 V-SNARE_C PF12352.3 CBZ25330.1 - 2.9e-09 36.8 218.0 5.9 7.0 1.6 29.5 2 1 25 33 33 33 12 Snare region anchored in the vesicle membrane C-terminus IFT57 PF10498.4 CBZ25330.1 - 1e-06 27.7 374.0 0.54 8.9 10.0 22.2 2 1 26 29 29 28 18 Intra-flagellar transport protein 57 TMF_DNA_bd PF12329.3 CBZ25330.1 - 5.8e-05 22.8 600.2 0.0056 16.4 10.4 32.5 7 1 35 42 42 42 36 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 CBZ25330.1 - 0.0004 20.3 436.7 0.33 10.9 13.5 28.0 3 2 26 30 30 27 3 Domain of unknown function (DUF4200) IncA PF04156.9 CBZ25330.1 - 0.0011 18.5 524.9 11 5.5 16.7 18.7 1 1 7 11 11 7 0 IncA protein PRP38_assoc PF12871.2 CBZ25330.1 - 0.058 13.9 4.1 1.6e+02 2.9 2.8 7.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Atg14 PF10186.4 CBZ25330.1 - 0.78 8.6 367.4 0.73 8.7 15.4 16.8 2 2 17 19 19 15 0 UV radiation resistance protein and autophagy-related subunit 14 Kinesin PF00225.18 CBZ25331.1 - 8.5e-80 267.9 0.3 3.1e-79 266.1 0.0 2.1 2 0 0 2 2 1 1 Kinesin motor domain Laminin_I PF06008.9 CBZ25331.1 - 6.9e-09 35.4 105.6 0.00085 18.7 11.1 7.5 2 1 4 7 7 6 5 Laminin Domain I Spc7 PF08317.6 CBZ25331.1 - 6.4e-07 28.3 95.6 0.0032 16.1 14.9 5.3 1 1 4 5 5 5 5 Spc7 kinetochore protein Laminin_II PF06009.7 CBZ25331.1 - 0.00014 21.5 82.2 0.81 9.4 5.5 8.3 3 1 4 8 8 8 4 Laminin Domain II Reo_sigmaC PF04582.7 CBZ25331.1 - 0.0002 20.6 62.2 0.17 11.0 8.5 6.1 2 1 4 7 7 7 5 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 CBZ25331.1 - 0.00044 20.0 132.3 0.0067 16.2 10.5 9.8 4 1 6 10 10 10 8 TATA element modulatory factor 1 DNA binding APG17 PF04108.7 CBZ25331.1 - 0.00056 18.8 25.6 0.00056 18.8 17.7 4.4 2 1 3 5 5 5 1 Autophagy protein Apg17 Tropomyosin PF00261.15 CBZ25331.1 - 0.00084 18.5 47.0 0.00084 18.5 32.6 5.3 2 1 4 6 6 5 1 Tropomyosin V-SNARE_C PF12352.3 CBZ25331.1 - 0.0092 16.0 38.8 2.6 8.1 2.1 7.5 3 1 5 8 8 8 5 Snare region anchored in the vesicle membrane C-terminus IFT57 PF10498.4 CBZ25331.1 - 0.011 14.4 82.3 0.36 9.5 10.3 6.4 2 1 6 8 8 8 0 Intra-flagellar transport protein 57 COG2 PF06148.6 CBZ25331.1 - 0.065 13.1 68.0 0.68 9.8 1.3 9.2 2 1 6 9 9 9 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 CBZ25331.1 - 0.11 12.0 123.4 8.8 5.8 22.0 5.4 1 1 2 3 3 2 0 IncA protein DUF4200 PF13863.1 CBZ25331.1 - 0.13 12.2 104.3 0.75 9.7 13.5 8.2 2 1 5 7 7 7 0 Domain of unknown function (DUF4200) Filament PF00038.16 CBZ25331.1 - 0.55 9.6 110.7 0.037 13.4 17.1 5.8 2 1 3 5 5 4 0 Intermediate filament protein Atg14 PF10186.4 CBZ25331.1 - 0.59 9.0 82.7 0.32 9.9 15.0 4.9 1 1 4 5 5 5 0 UV radiation resistance protein and autophagy-related subunit 14 Cast PF10174.4 CBZ25331.1 - 2.7 5.9 107.5 0.27 9.2 27.9 3.2 1 1 2 3 3 3 0 RIM-binding protein of the cytomatrix active zone AAA_13 PF13166.1 CBZ25331.1 - 3.7 5.9 77.8 0.055 11.9 9.7 3.6 2 1 3 5 5 5 0 AAA domain FtsH_ext PF06480.10 CBZ25332.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 FtsH Extracellular Phage_term_sma PF07141.6 CBZ25333.1 - 0.07 12.6 0.1 0.11 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit PhageMin_Tail PF10145.4 CBZ25334.1 - 0.2 11.2 6.1 0.36 10.4 4.3 1.4 1 0 0 1 1 1 0 Phage-related minor tail protein zf-met2 PF12907.2 CBZ25335.1 - 2 8.4 4.2 24 5.0 0.7 2.4 2 0 0 2 2 2 0 Zinc-binding ERO1 PF04137.10 CBZ25337.1 - 7.4e-95 317.9 0.0 8.7e-95 317.7 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DNA_pol_B PF00136.16 CBZ25338.1 - 1.8e-121 406.2 0.0 2.5e-121 405.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBZ25338.1 - 5e-34 117.6 0.0 8.2e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 CBZ25338.1 - 0.088 12.1 4.5 0.24 10.7 1.3 2.4 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger WD40 PF00400.27 CBZ25339.1 - 7.1e-24 82.7 2.4 0.00012 21.7 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat gpW PF02831.10 CBZ25339.1 - 0.019 14.5 0.8 0.53 9.8 0.1 3.3 1 1 1 2 2 2 0 gpW KIP1 PF07765.7 CBZ25339.1 - 0.049 13.4 1.9 0.16 11.8 0.4 2.6 2 0 0 2 2 2 0 KIP1-like protein Reo_sigmaC PF04582.7 CBZ25339.1 - 9.6 5.2 12.0 0.41 9.7 0.8 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein PPR_3 PF13812.1 CBZ25340.1 - 0.031 14.5 2.0 30 5.2 0.0 4.8 5 0 0 5 5 5 0 Pentatricopeptide repeat domain RRN3 PF05327.6 CBZ25340.1 - 0.074 11.1 0.0 3.2 5.7 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 FAD_binding_8 PF08022.7 CBZ25340.1 - 0.13 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 FAD-binding domain Kinesin PF00225.18 CBZ25342.1 - 1.6e-70 237.4 0.0 4.9e-69 232.5 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Mcp5_PH PF12814.2 CBZ25342.1 - 0.013 15.3 0.0 0.075 12.9 0.0 2.3 1 1 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology AAA_10 PF12846.2 CBZ25342.1 - 0.27 10.6 2.6 0.51 9.7 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 CBZ25342.1 - 0.74 9.9 2.6 30 4.7 0.2 2.6 2 0 0 2 2 2 0 AAA domain RRM_6 PF14259.1 CBZ25343.1 - 1.3e-15 57.1 0.1 2e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ25343.1 - 2.2e-13 49.6 0.0 3.3e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ25343.1 - 1.9e-06 27.5 0.1 3.2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIF4G PF02854.14 CBZ25344.1 - 2.2e-30 105.6 3.3 3.2e-30 105.1 2.3 1.2 1 0 0 1 1 1 1 MIF4G domain Band_7 PF01145.20 CBZ25345.1 - 4.2e-22 78.9 1.7 4.2e-22 78.9 1.2 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF4200 PF13863.1 CBZ25345.1 - 0.019 14.9 2.8 0.019 14.9 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) WD40 PF00400.27 CBZ25346.1 - 0.00041 20.1 12.2 0.022 14.6 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nop PF01798.13 CBZ25347.1 - 6.4e-12 45.0 1.3 2.5e-11 43.1 0.9 2.0 1 1 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 CBZ25347.1 - 0.0062 16.9 2.9 0.0062 16.9 2.0 1.7 2 0 0 2 2 2 1 Prp31 C terminal domain TipAS PF07739.8 CBZ25347.1 - 4.1 7.7 7.8 16 5.8 1.1 3.0 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain TPR_12 PF13424.1 CBZ25348.1 - 3.9e-09 36.3 8.7 0.16 11.9 0.0 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ25348.1 - 5.1e-06 26.0 1.7 2.1 8.0 0.0 5.7 5 2 2 7 7 7 2 TPR repeat eIF3_p135 PF12807.2 CBZ25348.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 IQ PF00612.22 CBZ25348.1 - 0.18 11.5 15.5 1.8 8.4 1.6 4.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif TPR_2 PF07719.12 CBZ25348.1 - 5.7 7.1 11.1 78 3.5 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat CLU PF13236.1 CBZ25349.1 - 3.5e-09 36.4 0.2 3e-07 30.1 0.2 2.7 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 CBZ25349.1 - 0.00049 20.0 0.0 0.00083 19.3 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 IucA_IucC PF04183.7 CBZ25350.1 - 3.5e-12 46.1 75.6 7.4 5.7 0.1 18.4 18 0 0 18 18 18 18 IucA / IucC family CLU PF13236.1 CBZ25350.1 - 3.9e-09 36.2 0.1 3.9e-08 32.9 0.1 2.3 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 CBZ25350.1 - 0.0039 17.1 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 DUF2518 PF10726.4 CBZ25350.1 - 0.42 10.1 0.0 1.3 8.5 0.0 1.8 1 0 0 1 1 1 0 Protein of function (DUF2518) DUF318 PF03773.8 CBZ25350.1 - 3.7 6.4 0.0 6.2 5.7 0.0 1.2 1 0 0 1 1 1 0 Predicted permease Swi5 PF07061.6 CBZ25351.1 - 0.13 12.0 6.6 1.1 9.1 3.6 2.9 2 0 0 2 2 2 0 Swi5 DUF3522 PF12036.3 CBZ25352.1 - 2.2e-58 197.1 13.6 2.6e-58 196.8 9.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF3522 PF12036.3 CBZ25353.1 - 2.2e-57 193.8 2.5 2.2e-57 193.8 1.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3522) 7TMR-DISM_7TM PF07695.6 CBZ25353.1 - 0.042 13.5 9.2 0.054 13.1 0.3 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling BatA PF07584.6 CBZ25353.1 - 0.24 11.6 0.2 0.24 11.6 0.1 2.3 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal zf-RING_2 PF13639.1 CBZ25354.1 - 1.4e-11 43.9 7.8 3.6e-11 42.7 5.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ25354.1 - 5.1e-09 36.0 6.9 1.1e-08 34.9 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ25354.1 - 5.8e-08 32.7 6.0 5.8e-08 32.7 4.2 2.3 2 2 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBZ25354.1 - 7.9e-08 31.8 6.7 1.6e-07 30.8 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ25354.1 - 8.5e-08 31.7 3.7 2.4e-07 30.3 2.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ25354.1 - 6.4e-06 25.7 4.9 1.7e-05 24.4 3.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ25354.1 - 2.4e-05 24.1 6.4 5.5e-05 22.9 4.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBZ25354.1 - 2.5e-05 24.0 1.3 2.5e-05 24.0 0.9 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CBZ25354.1 - 6.5e-05 22.5 5.4 0.00012 21.6 3.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger CpXC PF14353.1 CBZ25354.1 - 0.0024 17.8 0.4 0.0045 16.9 0.3 1.5 1 0 0 1 1 1 1 CpXC protein zf-RING_6 PF14835.1 CBZ25354.1 - 0.022 14.5 2.8 0.1 12.3 1.5 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 CBZ25354.1 - 0.091 12.3 5.0 2.9 7.4 0.2 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.3 CBZ25354.1 - 0.12 11.9 2.9 0.3 10.6 2.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 CBZ25354.1 - 0.17 11.8 8.6 2.5 8.1 4.1 3.0 1 1 1 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 CBZ25354.1 - 0.21 11.6 4.1 0.77 9.8 2.8 2.1 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 CBZ25354.1 - 9.8 6.2 8.1 7.7 6.6 4.0 2.1 2 1 0 2 2 1 0 RING-like domain DnaJ PF00226.26 CBZ25355.1 - 9.6e-08 31.6 0.0 1.6e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain UPF0258 PF06789.7 CBZ25355.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF4160 PF13711.1 CBZ25356.1 - 0.07 12.9 0.4 0.18 11.7 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) GCR1_C PF12550.3 CBZ25356.1 - 0.48 10.3 3.8 0.23 11.3 0.9 1.7 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Pkinase PF00069.20 CBZ25357.1 - 1.1e-68 231.2 0.0 1.4e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25357.1 - 1.5e-39 135.6 0.0 2.1e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.1 CBZ25357.1 - 8.8e-06 25.2 1.5 0.25 11.5 0.1 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 CBZ25357.1 - 2.2e-05 23.9 0.2 6.9e-05 22.3 0.1 1.9 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) Kinase-like PF14531.1 CBZ25357.1 - 6.5e-05 22.0 0.0 0.0001 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_1 PF00560.28 CBZ25357.1 - 0.0019 17.9 2.4 2 8.7 0.1 3.5 3 1 0 3 3 3 2 Leucine Rich Repeat RIO1 PF01163.17 CBZ25357.1 - 0.0092 15.3 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBZ25357.1 - 0.018 14.7 0.0 1.4 8.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PACT_coil_coil PF10495.4 CBZ25357.1 - 0.053 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein LRR_8 PF13855.1 CBZ25357.1 - 0.064 13.0 0.8 0.2 11.4 0.6 1.8 1 1 0 1 1 1 0 Leucine rich repeat Arf PF00025.16 CBZ25358.1 - 1.6e-69 232.6 0.0 1.9e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBZ25358.1 - 3.3e-11 42.7 0.0 3.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CBZ25358.1 - 3.3e-10 39.1 0.3 6.1e-08 31.7 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBZ25358.1 - 1.6e-09 37.2 0.0 1.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CBZ25358.1 - 2e-09 37.0 0.0 2.4e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ25358.1 - 2.4e-07 31.2 0.0 3.7e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBZ25358.1 - 2.4e-06 27.4 0.0 3.5e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ25358.1 - 0.021 14.1 0.7 0.13 11.5 0.5 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBZ25359.1 - 3.1e-54 183.2 0.0 5.5e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ25359.1 - 5.6e-36 122.6 0.1 3.6e-35 120.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ25359.1 - 6.3e-18 64.6 0.4 6.3e-18 64.6 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ25359.1 - 1.8e-05 24.2 0.2 5.4e-05 22.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBZ25359.1 - 3.9e-05 23.5 0.0 0.00014 21.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ25359.1 - 0.0047 16.1 0.1 0.032 13.4 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ25359.1 - 0.006 17.0 0.3 0.07 13.6 0.2 2.4 1 1 0 1 1 1 1 Miro-like protein Semialdhyde_dhC PF02774.13 CBZ25359.1 - 0.018 14.8 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.22 CBZ25360.1 - 3.1e-54 183.2 0.0 5.5e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ25360.1 - 5.6e-36 122.6 0.1 3.6e-35 120.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ25360.1 - 6.3e-18 64.6 0.4 6.3e-18 64.6 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ25360.1 - 1.8e-05 24.2 0.2 5.4e-05 22.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBZ25360.1 - 3.9e-05 23.5 0.0 0.00014 21.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ25360.1 - 0.0047 16.1 0.1 0.032 13.4 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ25360.1 - 0.006 17.0 0.3 0.07 13.6 0.2 2.4 1 1 0 1 1 1 1 Miro-like protein Semialdhyde_dhC PF02774.13 CBZ25360.1 - 0.018 14.8 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.22 CBZ25361.1 - 3.1e-54 183.2 0.0 5.5e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ25361.1 - 5.6e-36 122.6 0.1 3.6e-35 120.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ25361.1 - 6.3e-18 64.6 0.4 6.3e-18 64.6 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ25361.1 - 1.8e-05 24.2 0.2 5.4e-05 22.7 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBZ25361.1 - 3.9e-05 23.5 0.0 0.00014 21.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ25361.1 - 0.0047 16.1 0.1 0.032 13.4 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ25361.1 - 0.006 17.0 0.3 0.07 13.6 0.2 2.4 1 1 0 1 1 1 1 Miro-like protein Semialdhyde_dhC PF02774.13 CBZ25361.1 - 0.018 14.8 0.1 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU PF00009.22 CBZ25362.1 - 3.8e-54 182.9 0.2 4.7e-54 182.6 0.1 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ25362.1 - 5.6e-06 26.2 0.0 2.1e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ25362.1 - 0.00079 18.6 0.3 0.0056 15.9 0.1 2.4 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ25362.1 - 0.00094 19.6 0.8 0.015 15.8 0.3 2.4 2 1 0 2 2 2 1 Miro-like protein FlpD PF02662.11 CBZ25362.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Dynamin_N PF00350.18 CBZ25362.1 - 0.083 12.6 0.0 6.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Dynamin family GTP_EFTU_D3 PF03143.12 CBZ25363.1 - 6.3e-37 125.7 0.1 7.5e-36 122.2 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ25363.1 - 1.2e-18 66.9 1.3 1.8e-18 66.4 0.3 1.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ25363.1 - 9.4e-06 25.1 0.2 2.6e-05 23.7 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Semialdhyde_dhC PF02774.13 CBZ25363.1 - 0.0064 16.3 0.2 0.039 13.7 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain 5HT_transporter PF03491.8 CBZ25363.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus GTP_EFTU PF00009.22 CBZ25364.1 - 2.6e-54 183.5 0.0 4.4e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ25364.1 - 7.1e-26 90.2 0.1 5.5e-25 87.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ25364.1 - 5.5e-18 64.8 0.4 5.5e-18 64.8 0.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CBZ25364.1 - 1.8e-05 24.3 0.2 4.7e-05 22.9 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CBZ25364.1 - 3.5e-05 23.7 0.0 0.00012 22.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ25364.1 - 0.0039 16.4 0.1 0.022 13.9 0.0 2.3 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ25364.1 - 0.0048 17.3 0.3 0.06 13.8 0.2 2.4 1 1 0 1 1 1 1 Miro-like protein FlpD PF02662.11 CBZ25364.1 - 0.11 12.2 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit GTP_EFTU PF00009.22 CBZ25365.1 - 9e-38 129.5 0.3 9.6e-38 129.4 0.2 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ25365.1 - 1.1e-05 25.3 0.1 4e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ25365.1 - 0.00027 21.4 0.4 0.0041 17.5 0.3 2.0 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CBZ25365.1 - 0.0017 17.5 0.1 0.0081 15.4 0.0 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CBZ25365.1 - 0.026 14.3 0.2 3.7 7.3 0.1 2.1 1 1 0 2 2 2 0 Dynamin family Guanylate_cyc PF00211.15 CBZ25366.1 - 6.7e-39 133.1 0.0 1.9e-38 131.7 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.15 CBZ25367.1 - 9.2e-38 129.4 0.0 1.5e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.1 CBZ25367.1 - 4.9e-10 39.2 0.6 2.4e-07 30.4 0.0 2.7 2 0 0 2 2 2 2 Periplasmic binding protein Guanylate_cyc PF00211.15 CBZ25368.1 - 2.9e-38 131.0 0.0 6.8e-38 129.8 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Guanylate_cyc PF00211.15 CBZ25369.1 - 4.1e-38 130.5 0.0 7e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.1 CBZ25370.1 - 5.8e-05 22.6 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Guanylate_cyc PF00211.15 CBZ25371.1 - 5.9e-39 133.3 0.0 1e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_MLP1_2 PF07926.7 CBZ25373.1 - 0.0062 16.2 11.5 0.0062 16.2 8.0 2.0 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF1640 PF07798.6 CBZ25373.1 - 0.51 10.3 18.2 0.025 14.6 5.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1640) SlyX PF04102.7 CBZ25373.1 - 1.9 8.9 24.3 5.8 7.3 0.7 4.7 3 2 1 4 4 4 0 SlyX DUF972 PF06156.8 CBZ25373.1 - 2.8 8.3 16.8 0.73 10.2 0.1 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF972) TPR_2 PF07719.12 CBZ25374.1 - 8.7e-17 59.6 0.4 0.00023 20.8 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ25374.1 - 1.4e-13 50.2 0.4 3.9e-07 29.6 0.4 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 CBZ25374.1 - 3.1e-10 39.8 3.0 0.00036 20.3 0.7 4.1 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ25374.1 - 1.5e-09 36.9 1.9 0.02 14.6 0.5 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ25374.1 - 7.4e-09 34.8 2.8 0.0097 15.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ25374.1 - 2.9e-07 30.1 0.2 1.3 9.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ25374.1 - 5.8e-06 26.8 0.1 0.12 13.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ25374.1 - 7.5e-06 26.1 0.2 0.0011 19.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ25374.1 - 1.1e-05 25.6 0.4 5.3 7.9 0.0 4.3 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ25374.1 - 1.2e-05 25.3 0.3 0.16 12.4 0.0 5.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ25374.1 - 0.00012 21.5 3.6 0.67 9.8 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ25374.1 - 0.0007 19.6 3.9 0.13 12.3 0.0 3.2 1 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CBZ25374.1 - 0.0015 18.3 0.7 1.2 9.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 CBZ25374.1 - 0.039 13.9 0.9 1.7 8.5 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat SLT PF01464.15 CBZ25374.1 - 0.11 11.9 0.3 0.31 10.5 0.1 1.7 2 0 0 2 2 2 0 Transglycosylase SLT domain Peptidase_M20 PF01546.23 CBZ25376.1 - 2.7e-12 46.6 0.1 4.5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ25376.1 - 2.4e-08 33.7 0.0 5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 CBZ25376.1 - 7.4e-06 24.9 0.1 6.5e-05 21.8 0.1 2.1 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 CBZ25376.1 - 6e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 DUF3508 PF12018.3 CBZ25377.1 - 0.00035 19.6 0.2 0.13 11.1 0.1 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF3508) Kinesin PF00225.18 CBZ25378.1 - 4.5e-39 134.0 0.0 1.9e-22 79.4 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Glyco_hydro_77 PF02446.12 CBZ25378.1 - 0.044 12.3 0.0 0.07 11.7 0.0 1.2 1 0 0 1 1 1 0 4-alpha-glucanotransferase AAA_22 PF13401.1 CBZ25378.1 - 0.16 12.1 0.0 0.55 10.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 CBZ25379.1 - 2e-34 116.2 17.9 6.8e-10 38.4 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 CBZ25379.1 - 9.7e-06 23.9 1.9 0.0059 14.8 0.1 3.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 CBZ25379.1 - 5.4e-05 22.7 0.0 0.51 10.0 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 CBZ25379.1 - 0.0037 15.5 0.0 0.013 13.8 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3312) PQQ_2 PF13360.1 CBZ25379.1 - 0.084 12.3 0.1 13 5.1 0.0 2.7 2 1 0 2 2 2 0 PQQ-like domain Cytochrom_D1 PF02239.11 CBZ25379.1 - 0.12 10.6 0.0 0.35 9.1 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 CBZ25379.1 - 0.15 11.4 0.3 5.9 6.3 0.1 2.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature RCC1 PF00415.13 CBZ25380.1 - 2.5e-49 165.2 43.3 1.1e-13 51.1 0.7 8.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ25380.1 - 7.1e-34 114.6 43.9 5.8e-12 44.8 2.8 8.1 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat BTB_2 PF02214.17 CBZ25380.1 - 6.6e-06 26.2 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain CBM_X PF06204.6 CBZ25380.1 - 0.59 9.6 2.6 33 4.0 0.3 3.6 3 0 0 3 3 3 0 Putative carbohydrate binding domain PALP PF00291.20 CBZ25381.1 - 9.3e-61 205.7 0.1 1.1e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2Fe-2S_thioredx PF01257.14 CBZ25383.1 - 1.5e-48 164.1 0.0 2.2e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Histone PF00125.19 CBZ25384.1 - 5.5e-15 55.2 0.1 8.4e-15 54.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_2 PF13923.1 CBZ25385.1 - 6.3e-08 32.5 16.6 6.3e-08 32.5 11.5 3.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ25385.1 - 9.9e-08 31.5 17.5 9.9e-08 31.5 12.1 3.5 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ25385.1 - 3.9e-05 23.2 14.2 3.9e-05 23.2 9.8 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ25385.1 - 0.00014 21.6 14.9 0.00014 21.6 10.3 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBZ25385.1 - 0.00065 19.4 19.2 0.00065 19.4 13.3 3.8 5 0 0 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.1 CBZ25385.1 - 0.0066 16.1 12.4 0.017 14.7 8.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger LSM PF01423.17 CBZ25386.1 - 4.8e-05 22.8 0.0 0.00019 20.9 0.0 1.8 1 1 0 1 1 1 1 LSM domain SPRR2 PF14820.1 CBZ25388.1 - 1.5 8.7 8.7 0.72 9.7 1.7 2.5 2 0 0 2 2 2 0 Small proline-rich 2 dsrm PF00035.20 CBZ25389.1 - 0.0066 16.9 0.0 10 6.8 0.0 3.0 3 0 0 3 3 3 2 Double-stranded RNA binding motif Cadherin_2 PF08266.7 CBZ25390.1 - 0.022 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Cadherin-like Dus PF01207.12 CBZ25391.1 - 3.9e-49 167.1 1.8 5.3e-49 166.7 0.0 2.0 3 0 0 3 3 3 1 Dihydrouridine synthase (Dus) DUF4105 PF13387.1 CBZ25391.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Neur_chan_memb PF02932.11 CBZ25391.1 - 0.87 9.4 3.0 1.5 8.6 2.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mucin PF01456.12 CBZ25391.1 - 1.6 8.4 16.1 3.4 7.4 7.7 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein dCMP_cyt_deam_1 PF00383.17 CBZ25392.1 - 2.2e-12 46.5 3.7 3.1e-12 46.0 2.5 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CBZ25392.1 - 4.4e-08 33.1 0.4 5.8e-06 26.3 0.4 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 CBZ25392.1 - 0.0024 17.2 5.6 0.0049 16.2 3.8 1.7 1 1 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases Thioredoxin PF00085.15 CBZ25392.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Dockerin_1 PF00404.13 CBZ25393.1 - 0.35 10.6 1.0 0.88 9.3 0.7 1.7 1 0 0 1 1 1 0 Dockerin type I repeat Sec20 PF03908.8 CBZ25394.1 - 2e-06 27.4 0.4 2e-06 27.4 0.2 2.0 3 0 0 3 3 3 1 Sec20 DUF883 PF05957.8 CBZ25394.1 - 0.0029 17.9 0.3 0.0029 17.9 0.2 2.9 2 2 0 2 2 2 1 Bacterial protein of unknown function (DUF883) V-SNARE_C PF12352.3 CBZ25394.1 - 0.0037 17.3 1.9 0.0037 17.3 1.3 1.8 2 0 0 2 2 1 1 Snare region anchored in the vesicle membrane C-terminus Prominin PF05478.6 CBZ25394.1 - 0.0091 13.5 0.6 0.016 12.7 0.4 1.3 1 0 0 1 1 1 1 Prominin Spore_III_AB PF09548.5 CBZ25394.1 - 0.033 13.9 1.3 3.1 7.5 0.1 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) V-SNARE PF05008.10 CBZ25394.1 - 0.035 14.2 4.9 0.085 13.0 0.1 2.6 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Med11 PF10280.4 CBZ25394.1 - 0.039 13.9 2.2 0.061 13.3 0.0 2.1 2 1 0 2 2 2 0 Mediator complex protein DUF2216 PF10226.4 CBZ25394.1 - 0.06 12.8 0.2 0.06 12.8 0.1 2.3 2 1 1 3 3 3 0 Uncharacterized conserved proteins (DUF2216) Baculo_11_kDa PF06143.6 CBZ25394.1 - 0.082 12.2 0.1 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Spc7 PF08317.6 CBZ25394.1 - 0.085 11.5 3.9 0.17 10.5 0.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Synaptobrevin PF00957.16 CBZ25394.1 - 0.12 12.0 4.0 0.39 10.3 2.5 2.1 1 1 0 1 1 1 0 Synaptobrevin HR1 PF02185.11 CBZ25394.1 - 0.16 11.7 0.0 0.16 11.7 0.0 3.3 5 0 0 5 5 5 0 Hr1 repeat Transcrip_act PF04949.8 CBZ25394.1 - 0.62 9.6 3.8 0.63 9.6 0.4 2.2 2 1 0 2 2 2 0 Transcriptional activator DUF3450 PF11932.3 CBZ25394.1 - 0.76 9.0 9.8 0.27 10.4 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) CENP-H PF05837.7 CBZ25394.1 - 2.7 8.2 7.5 0.79 9.9 1.5 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FliJ PF02050.11 CBZ25394.1 - 3.2 7.8 15.5 2.5 8.1 1.7 2.6 3 0 0 3 3 3 0 Flagellar FliJ protein MTBP_C PF14920.1 CBZ25394.1 - 3.9 6.8 8.6 0.25 10.7 1.6 1.9 1 1 0 2 2 2 0 MDM2-binding KxDL PF10241.4 CBZ25394.1 - 5 7.0 7.2 0.68 9.8 1.5 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein Pkinase PF00069.20 CBZ25395.1 - 9.6e-59 198.6 0.0 2.2e-58 197.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25395.1 - 1e-39 136.1 0.0 2.4e-38 131.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25395.1 - 2e-07 30.2 0.0 4e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ25395.1 - 0.0055 16.4 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ25395.1 - 0.0097 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ANTH PF07651.11 CBZ25395.1 - 0.034 12.8 0.0 0.077 11.6 0.0 1.5 1 0 0 1 1 1 0 ANTH domain zf-RING_2 PF13639.1 CBZ25396.1 - 1.1e-10 41.1 8.1 1.1e-10 41.1 5.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CBZ25396.1 - 0.00075 19.1 6.3 0.00075 19.1 4.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBZ25396.1 - 0.0028 17.6 8.2 0.012 15.6 5.7 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ25396.1 - 0.0029 17.2 6.7 0.0029 17.2 4.6 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ25396.1 - 0.004 17.2 2.5 0.004 17.2 1.7 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBZ25396.1 - 0.0077 15.8 5.2 0.0077 15.8 3.6 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) CbiN PF02553.10 CBZ25396.1 - 0.025 14.5 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 Cobalt transport protein component CbiN zf-Nse PF11789.3 CBZ25396.1 - 0.14 11.7 3.1 0.36 10.3 2.2 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 CBZ25396.1 - 0.71 9.7 13.9 0.22 11.3 5.8 3.0 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING N6-adenineMlase PF10237.4 CBZ25398.1 - 3.5e-43 147.0 1.2 5.5e-43 146.4 0.9 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase SoxD PF04267.7 CBZ25398.1 - 0.03 14.1 0.2 0.37 10.6 0.1 2.5 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family Methyltransf_26 PF13659.1 CBZ25398.1 - 0.084 12.9 0.7 0.26 11.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Ammonium_transp PF00909.16 CBZ25399.1 - 6.8 5.0 5.3 11 4.3 3.7 1.2 1 0 0 1 1 1 0 Ammonium Transporter Family IncA PF04156.9 CBZ25400.1 - 0.057 13.0 0.2 0.057 13.0 0.1 3.6 4 0 0 4 4 4 0 IncA protein Atg14 PF10186.4 CBZ25400.1 - 1.3 7.9 9.9 64 2.3 8.2 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CASP_C PF08172.7 CBZ25401.1 - 0.13 11.2 0.4 8.5 5.3 0.1 2.3 2 0 0 2 2 2 0 CASP C terminal DnaJ PF00226.26 CBZ25402.1 - 5.3e-12 45.2 0.0 9.9e-12 44.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Selenoprotein_S PF06936.6 CBZ25402.1 - 0.38 10.2 2.6 0.69 9.4 1.8 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) AAA_27 PF13514.1 CBZ25403.1 - 0.16 9.5 11.2 0.3 8.7 7.8 1.3 1 0 0 1 1 1 0 AAA domain PhzC-PhzF PF02567.11 CBZ25404.1 - 8.5e-36 123.6 3.3 7.9e-14 51.5 0.0 4.9 4 1 0 4 4 4 4 Phenazine biosynthesis-like protein Sigma70_r4 PF04545.11 CBZ25404.1 - 0.0058 15.9 0.0 0.015 14.6 0.0 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 Pkinase PF00069.20 CBZ25405.1 - 1.3e-57 194.9 0.0 1.7e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25405.1 - 3.3e-39 134.5 0.0 6.4e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIF_alpha PF05793.7 CBZ25405.1 - 0.0066 14.8 16.5 0.011 14.1 11.4 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Kinase-like PF14531.1 CBZ25405.1 - 0.03 13.2 0.0 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.11 CBZ25405.1 - 0.13 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 ABC1 family BUD22 PF09073.5 CBZ25405.1 - 0.13 11.2 29.8 0.21 10.6 20.7 1.2 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.8 CBZ25405.1 - 0.45 10.3 20.8 0.017 15.0 9.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 CBZ25405.1 - 0.76 8.1 23.0 1.4 7.2 16.0 1.4 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CBZ25405.1 - 1 7.2 26.4 1.5 6.6 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 CBZ25405.1 - 3.7 6.7 24.3 5.9 6.0 16.8 1.2 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.4 CBZ25405.1 - 7.8 5.1 30.4 1.4 7.5 18.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 CBZ25405.1 - 8.3 4.3 18.2 15 3.4 12.6 1.4 1 0 0 1 1 1 0 CDC45-like protein IncA PF04156.9 CBZ25409.1 - 0.00012 21.7 13.9 0.00012 21.7 9.6 3.6 3 0 0 3 3 3 1 IncA protein Uds1 PF15456.1 CBZ25409.1 - 0.067 13.1 58.8 0.043 13.8 7.7 6.2 5 1 2 7 7 7 0 Up-regulated During Septation Sirohm_synth_C PF14823.1 CBZ25409.1 - 0.071 12.4 0.2 0.46 9.8 0.0 2.2 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal zf-ZPR1 PF03367.8 CBZ25409.1 - 0.091 11.9 2.7 0.22 10.6 0.2 2.4 2 0 0 2 2 2 0 ZPR1 zinc-finger domain DUF3439 PF11921.3 CBZ25409.1 - 0.41 10.4 13.8 0.11 12.2 0.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) AAA_13 PF13166.1 CBZ25409.1 - 4.8 5.5 16.4 0.44 8.9 8.2 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CBZ25410.1 - 1.9e-09 37.8 0.0 7.3e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBZ25410.1 - 8.5e-07 28.0 0.1 0.0037 16.0 0.0 2.8 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CBZ25410.1 - 7.3e-06 26.8 0.0 2.2e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ25410.1 - 8.8e-06 25.8 0.2 5.3e-05 23.3 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 CBZ25410.1 - 2.2e-05 24.1 3.5 2.2e-05 24.1 2.4 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 CBZ25410.1 - 9.8e-05 22.1 0.0 0.0034 17.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CBZ25410.1 - 0.00022 21.2 0.1 0.00022 21.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ25410.1 - 0.00038 20.7 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ25410.1 - 0.00042 20.3 0.0 0.00042 20.3 0.0 2.8 4 0 0 4 4 2 1 AAA ATPase domain AAA_33 PF13671.1 CBZ25410.1 - 0.0013 18.5 1.9 0.0033 17.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBZ25410.1 - 0.0016 17.5 0.1 0.0029 16.7 0.1 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 CBZ25410.1 - 0.002 17.3 0.0 0.0043 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CBZ25410.1 - 0.0021 17.7 0.1 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 NTPase AAA_25 PF13481.1 CBZ25410.1 - 0.005 16.2 0.0 0.026 13.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBZ25410.1 - 0.022 14.6 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CBZ25410.1 - 0.092 12.1 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 CBZ25410.1 - 0.14 11.8 0.0 0.38 10.4 0.0 1.8 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 CBZ25410.1 - 0.22 11.6 0.0 0.64 10.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 CBZ25410.1 - 0.27 10.7 0.0 0.48 9.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Polyoma_lg_T_C PF06431.6 CBZ25410.1 - 0.37 9.4 0.0 0.59 8.7 0.0 1.2 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus Arch_ATPase PF01637.13 CBZ25410.1 - 0.38 10.3 0.0 0.71 9.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase RRM_1 PF00076.17 CBZ25411.1 - 1.7e-13 49.9 0.9 6.7e-10 38.4 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ25411.1 - 1.7e-11 43.8 0.1 2.2e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ25411.1 - 3.7e-11 42.8 0.4 4e-07 29.9 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AsnC_trans_reg PF01037.16 CBZ25411.1 - 0.082 12.6 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 AsnC family ELF PF03317.8 CBZ25412.1 - 0.14 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 ELF protein Cep57_MT_bd PF06657.8 CBZ25413.1 - 0.48 10.3 12.1 0.9 9.5 3.9 3.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Syntaxin PF00804.20 CBZ25413.1 - 3.3 7.9 8.0 6.3 7.0 1.2 2.9 3 0 0 3 3 3 0 Syntaxin Metallophos PF00149.23 CBZ25414.1 - 4.2e-05 23.0 0.0 7.2e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBZ25414.1 - 0.038 13.8 0.1 0.062 13.1 0.1 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FliT PF05400.8 CBZ25415.1 - 3.4 8.1 14.6 0.32 11.4 5.2 2.8 2 0 0 2 2 2 0 Flagellar protein FliT E1-E2_ATPase PF00122.15 CBZ25416.1 - 4.4e-55 186.2 1.5 8.2e-55 185.3 1.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBZ25416.1 - 2.7e-39 134.5 5.4 2.7e-39 134.5 3.7 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBZ25416.1 - 2.2e-24 87.0 1.5 7.1e-19 69.0 0.1 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ25416.1 - 9.9e-16 57.4 0.0 2.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CBZ25416.1 - 8.2e-14 50.8 0.0 2e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 CBZ25416.1 - 1.4e-09 38.3 0.0 5.4e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBZ25416.1 - 0.00011 21.9 0.6 0.00019 21.0 0.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3667 PF12412.3 CBZ25416.1 - 0.18 11.1 0.0 0.39 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) ACBP PF00887.14 CBZ25417.1 - 4.7e-32 109.5 0.5 1.3e-19 69.6 0.0 3.0 2 1 0 2 2 2 2 Acyl CoA binding protein ACBP PF00887.14 CBZ25418.1 - 4.5e-29 99.9 0.2 5.4e-29 99.6 0.1 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Attacin_C PF03769.10 CBZ25418.1 - 0.055 13.6 0.1 0.15 12.2 0.1 1.6 1 1 1 2 2 2 0 Attacin, C-terminal region Ldl_recept_b PF00058.12 CBZ25419.1 - 0.089 13.1 0.1 15 5.9 0.0 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor repeat class B ACBP PF00887.14 CBZ25420.1 - 5.6e-30 102.8 0.4 6.3e-30 102.6 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4123 PF13503.1 CBZ25420.1 - 0.13 12.2 0.1 0.22 11.4 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4123) Abhydrolase_6 PF12697.2 CBZ25422.1 - 5.8e-09 36.1 1.7 7.8e-09 35.7 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ25422.1 - 0.00085 18.9 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CBZ25422.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CBZ25422.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CBZ25422.1 - 0.072 12.6 0.3 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 Serine hydrolase EF-hand_7 PF13499.1 CBZ25423.1 - 5.8e-15 55.1 0.0 1.3e-10 41.1 0.0 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ25423.1 - 7.5e-07 28.5 0.5 0.00096 18.8 0.0 3.4 3 1 1 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 CBZ25423.1 - 3.3e-05 23.0 0.1 0.00016 20.8 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.27 CBZ25423.1 - 6.2e-05 22.0 0.0 0.0011 18.1 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 CBZ25423.1 - 0.05 13.2 1.4 1.7 8.3 0.0 3.1 4 0 0 4 4 4 0 EF-hand domain pair DUF3767 PF12597.3 CBZ25424.1 - 0.06 13.0 0.3 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) GRAM PF02893.15 CBZ25425.1 - 3.7e-09 35.9 1.2 2.3e-06 27.0 0.1 2.5 2 0 0 2 2 2 2 GRAM domain Pkinase PF00069.20 CBZ25427.1 - 8e-67 225.1 0.0 1e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain POLO_box PF00659.13 CBZ25427.1 - 2.2e-43 146.0 0.0 1.4e-26 92.2 0.0 2.6 2 0 0 2 2 2 2 POLO box duplicated region Pkinase_Tyr PF07714.12 CBZ25427.1 - 3.9e-38 131.0 0.0 5.3e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25427.1 - 4.6e-10 38.9 0.0 2.6e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF4520 PF15016.1 CBZ25427.1 - 0.026 14.0 0.1 0.62 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) APH PF01636.18 CBZ25427.1 - 0.033 13.9 0.0 0.033 13.9 0.0 3.6 3 2 1 4 4 4 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBZ25427.1 - 0.09 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4404 PF14357.1 CBZ25427.1 - 0.69 10.3 3.0 0.67 10.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) VID27 PF08553.5 CBZ25428.1 - 9e-30 103.5 0.0 1.6e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 VID27 cytoplasmic protein DUF1922 PF09082.5 CBZ25429.1 - 0.18 11.9 0.1 0.45 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) Pkinase PF00069.20 CBZ25431.1 - 6.5e-22 77.9 0.0 3.2e-10 39.5 0.0 4.2 4 0 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25431.1 - 0.00049 19.2 0.0 0.19 10.7 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase NT5C PF06941.7 CBZ25432.1 - 0.0071 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Tudor-knot PF11717.3 CBZ25432.1 - 0.026 14.2 0.1 0.057 13.1 0.1 1.5 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF1284 PF06935.6 CBZ25433.1 - 0.24 11.5 1.0 17 5.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1284) Syntaxin-6_N PF09177.6 CBZ25433.1 - 1.9 8.9 6.6 0.39 11.1 0.4 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Methyltransf_16 PF10294.4 CBZ25434.1 - 3.4e-19 68.9 0.0 3.7e-14 52.5 0.0 2.6 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CBZ25434.1 - 0.00016 22.2 0.0 0.00036 21.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ25434.1 - 0.059 12.7 0.5 0.15 11.4 0.1 1.8 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 CBZ25434.1 - 0.063 13.3 0.2 0.19 11.7 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ25434.1 - 0.14 12.6 0.0 23 5.5 0.0 3.0 2 1 1 3 3 3 0 Methyltransferase domain Myb_DNA-binding PF00249.26 CBZ25435.1 - 3e-18 65.5 4.5 1.7e-10 40.7 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBZ25435.1 - 3e-14 52.8 10.7 2.8e-09 36.9 0.4 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain RNA_pol_Rpb2_7 PF04560.15 CBZ25435.1 - 0.069 13.4 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 Myb_DNA-bind_4 PF13837.1 CBZ25435.1 - 0.83 9.8 8.0 0.54 10.4 0.1 3.5 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain DUF2953 PF11167.3 CBZ25436.1 - 0.082 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) IMPDH PF00478.20 CBZ25437.1 - 4.4e-133 443.5 2.9 6.3e-133 443.0 2.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CBZ25437.1 - 2.2e-12 46.5 0.1 4.2e-06 26.4 0.0 2.9 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 CBZ25437.1 - 7.2e-08 31.6 7.2 1.4e-07 30.6 5.0 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 CBZ25437.1 - 3.8e-06 26.2 11.1 0.016 14.3 5.2 2.8 2 1 1 3 3 3 2 Nitronate monooxygenase PcrB PF01884.12 CBZ25437.1 - 0.0007 18.9 6.3 0.0076 15.5 0.1 3.0 2 1 0 2 2 2 1 PcrB family His_biosynth PF00977.16 CBZ25437.1 - 0.00092 18.5 2.8 0.014 14.6 0.1 2.3 1 1 1 2 2 2 1 Histidine biosynthesis protein DHO_dh PF01180.16 CBZ25437.1 - 0.0035 16.3 5.5 0.019 13.9 0.4 2.3 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.9 CBZ25437.1 - 0.0036 16.4 0.6 0.0036 16.4 0.4 2.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 CBZ25437.1 - 0.0054 15.6 4.2 0.0097 14.8 2.9 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Beta_elim_lyase PF01212.16 CBZ25437.1 - 0.0095 15.1 0.4 0.018 14.2 0.3 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase ParA PF10609.4 CBZ25437.1 - 0.015 15.1 1.4 2.9 7.8 0.0 3.3 3 0 0 3 3 3 0 ParA/MinD ATPase like Lysine_decarbox PF03641.9 CBZ25438.1 - 5.4e-28 97.4 0.1 8.5e-28 96.8 0.1 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase ABM PF03992.11 CBZ25438.1 - 4.6e-08 32.9 0.0 9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Kinesin PF00225.18 CBZ25439.1 - 1.6e-103 345.9 0.2 1.6e-103 345.9 0.1 2.2 2 1 1 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 CBZ25439.1 - 4.2 6.4 29.5 0.58 9.2 3.5 5.0 2 1 2 5 5 5 0 Reovirus sigma C capsid protein LPP PF04728.8 CBZ25440.1 - 0.091 12.5 0.6 2.8 7.8 0.1 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper G-patch PF01585.18 CBZ25441.1 - 2.7e-13 49.4 0.3 5.5e-13 48.4 0.2 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CBZ25441.1 - 0.00098 18.9 0.4 0.00098 18.9 0.3 1.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site Macoilin PF09726.4 CBZ25441.1 - 0.29 9.3 7.1 0.32 9.2 5.0 1.0 1 0 0 1 1 1 0 Transmembrane protein FLO_LFY PF01698.11 CBZ25441.1 - 1.2 7.9 5.8 1.5 7.5 4.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DBR1 PF05011.8 CBZ25443.1 - 6.7e-06 26.0 0.0 1.5e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CBZ25443.1 - 0.00095 18.6 0.1 0.0038 16.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBZ25443.1 - 0.0091 15.8 0.0 0.031 14.1 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ATP-synt_10 PF05176.9 CBZ25444.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 ATP10 protein DUF1935 PF09149.5 CBZ25447.1 - 3.7e-34 116.8 0.0 8.6e-34 115.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) META PF03724.11 CBZ25447.1 - 3.1e-24 84.7 0.5 1.2e-08 34.6 0.0 3.3 3 0 0 3 3 3 3 META domain META PF03724.11 CBZ25449.1 - 1.9e-11 43.6 0.0 2.2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 META domain LRR_6 PF13516.1 CBZ25450.1 - 4.4e-14 50.9 1.7 0.37 11.0 0.0 7.0 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.2 CBZ25450.1 - 8.6e-11 41.2 0.1 0.016 14.7 0.0 4.0 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ25450.1 - 1.7e-07 30.3 0.0 12 6.3 0.0 6.4 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ25450.1 - 0.00042 20.0 7.8 27 5.5 0.0 6.5 7 0 0 7 7 7 1 Leucine rich repeat LRR_8 PF13855.1 CBZ25450.1 - 0.00062 19.4 1.2 7.2 6.4 0.3 3.8 2 1 1 3 3 3 3 Leucine rich repeat Acyltransferase PF01553.16 CBZ25451.1 - 6.4e-13 48.2 0.0 1.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Sec63 PF02889.11 CBZ25452.1 - 5.5e-65 219.6 0.0 1.4e-57 195.3 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CBZ25452.1 - 7.2e-36 123.2 0.6 6e-27 94.1 0.4 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ25452.1 - 2.2e-08 33.8 0.0 6e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ25452.1 - 2.9e-08 33.7 0.0 1.9e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 CBZ25452.1 - 0.2 10.8 0.0 0.66 9.2 0.0 1.8 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain FH2 PF02181.18 CBZ25453.1 - 7.6e-51 173.1 0.0 1.1e-50 172.5 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Med9 PF07544.8 CBZ25453.1 - 2.1e-06 27.3 0.2 6.5e-06 25.8 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 CUE PF02845.11 CBZ25453.1 - 0.0041 16.5 0.0 0.0081 15.6 0.0 1.5 1 0 0 1 1 1 1 CUE domain CorA PF01544.13 CBZ25453.1 - 0.029 13.4 0.1 0.065 12.2 0.1 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FAM163 PF15069.1 CBZ25453.1 - 0.48 11.0 4.3 0.34 11.4 1.1 2.2 2 0 0 2 2 2 0 FAM163 family PCIF1_WW PF12237.3 CBZ25454.1 - 1.3e-34 119.0 0.1 4.1e-33 114.1 0.1 2.8 2 1 0 2 2 2 1 Phosphorylated CTD interacting factor 1 WW domain PDEase_I PF00233.14 CBZ25455.1 - 1.6e-10 41.1 0.5 2.5e-07 30.6 0.2 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase BTB PF00651.26 CBZ25456.1 - 0.017 15.0 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Mak10 PF04112.8 CBZ25457.1 - 1.1e-07 31.2 0.0 4.6e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase PI3_PI4_kinase PF00454.22 CBZ25458.1 - 0.00089 18.7 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF2126 PF09899.4 CBZ25458.1 - 0.012 13.7 0.0 0.019 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Abhydrolase_6 PF12697.2 CBZ25460.1 - 1.1e-21 77.8 0.9 1.7e-21 77.1 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ25460.1 - 2.8e-13 49.9 0.3 5.7e-12 45.6 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBZ25460.1 - 1.7e-11 44.0 0.0 2.5e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CBZ25460.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.8 CBZ25460.1 - 0.0022 17.4 0.6 0.0028 17.1 0.0 1.4 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 CBZ25460.1 - 0.011 14.9 0.1 0.071 12.3 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CBZ25460.1 - 0.03 13.7 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.15 CBZ25460.1 - 0.085 12.2 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase GlcNAc PF11397.3 CBZ25461.1 - 4.1e-135 450.3 0.0 5e-135 450.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) TFR_dimer PF04253.10 CBZ25462.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain DLIC PF05783.6 CBZ25462.1 - 3.9 6.0 4.7 8 4.9 3.2 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Abhydrolase_6 PF12697.2 CBZ25463.1 - 2.6e-23 83.0 5.4 9.4e-23 81.2 3.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ25463.1 - 1.4e-15 57.4 1.0 8e-15 55.0 0.7 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBZ25463.1 - 6.7e-12 45.3 0.1 7e-11 42.0 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 CBZ25463.1 - 6.6e-06 25.5 0.6 0.09 12.0 0.0 2.5 2 0 0 2 2 2 2 Esterase PHB depolymerase Abhydrolase_4 PF08386.5 CBZ25463.1 - 2.6e-05 24.0 0.0 7.2e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein Ndr PF03096.9 CBZ25463.1 - 5.3e-05 21.8 0.0 8.9e-05 21.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.8 CBZ25463.1 - 0.00059 19.4 0.0 0.13 11.7 0.0 2.8 3 0 0 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.15 CBZ25463.1 - 0.0015 17.9 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.8 CBZ25463.1 - 0.0027 17.3 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase FSH1 PF03959.8 CBZ25463.1 - 0.02 14.3 0.0 0.081 12.3 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF2048 PF09752.4 CBZ25463.1 - 0.022 13.6 0.1 0.48 9.2 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Patatin PF01734.17 CBZ25463.1 - 0.051 13.4 2.1 0.083 12.7 1.1 1.5 1 1 0 1 1 1 0 Patatin-like phospholipase Peptidase_S9 PF00326.16 CBZ25463.1 - 0.051 12.7 0.0 4.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 CBZ25464.1 - 6.4e-31 107.9 1.6 8.3e-31 107.6 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ25464.1 - 1.2e-17 64.2 0.0 2e-17 63.5 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBZ25464.1 - 2.7e-14 53.1 0.0 8e-14 51.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 CBZ25464.1 - 0.00015 21.0 0.1 0.035 13.3 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Esterase PF00756.15 CBZ25464.1 - 0.00017 21.0 0.0 0.00033 20.1 0.0 1.5 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.9 CBZ25464.1 - 0.00034 19.1 0.0 0.002 16.6 0.0 1.9 2 0 0 2 2 2 1 Ndr family Abhydrolase_4 PF08386.5 CBZ25464.1 - 0.00083 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 CBZ25464.1 - 0.0021 17.8 0.0 0.0049 16.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 CBZ25464.1 - 0.0035 16.8 0.0 0.28 10.6 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 CBZ25464.1 - 0.022 14.0 0.0 0.57 9.4 0.0 2.4 3 0 0 3 3 3 0 Dienelactone hydrolase family FIST PF08495.5 CBZ25464.1 - 0.023 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 FIST N domain Acyl_transf_2 PF02273.10 CBZ25464.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Acyl transferase Thioesterase PF00975.15 CBZ25464.1 - 0.13 12.4 0.1 0.27 11.4 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S9 PF00326.16 CBZ25464.1 - 0.15 11.2 0.0 6.4 5.9 0.0 2.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2048 PF09752.4 CBZ25464.1 - 0.16 10.8 0.7 0.24 10.2 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 CBZ25465.1 - 2e-23 83.4 3.3 2e-23 83.4 2.3 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ25465.1 - 3.8e-13 49.5 0.0 1.7e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBZ25465.1 - 6e-12 45.5 0.1 2.3e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 CBZ25465.1 - 0.002 18.3 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.5 CBZ25465.1 - 0.02 14.7 0.0 0.064 13.1 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.15 CBZ25465.1 - 0.06 12.7 0.0 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative esterase ThiG PF05690.9 CBZ25465.1 - 0.3 10.1 6.2 3.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PLAC8 PF04749.12 CBZ25466.1 - 1 9.9 15.2 0.99 9.9 8.6 2.3 2 1 0 2 2 2 0 PLAC8 family DUF4570 PF15134.1 CBZ25467.1 - 0.063 13.1 1.1 0.13 12.0 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Tropomyosin_1 PF12718.2 CBZ25467.1 - 0.064 13.0 3.9 0.11 12.3 2.7 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF4201 PF13870.1 CBZ25467.1 - 0.13 11.6 1.5 0.2 11.1 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) ADIP PF11559.3 CBZ25467.1 - 4.8 7.0 6.5 10 6.0 4.5 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding UCH PF00443.24 CBZ25468.1 - 1.7e-18 66.7 0.0 3.3e-18 65.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ25468.1 - 5.4e-09 35.9 0.0 6.1e-08 32.4 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Steroid_dh PF02544.11 CBZ25469.1 - 1.7e-24 86.3 1.3 7.7e-10 38.7 0.0 4.3 4 0 0 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase Kinesin PF00225.18 CBZ25470.1 - 5.5e-86 288.3 0.1 7.9e-86 287.7 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Calpain_III PF01067.17 CBZ25470.1 - 3.1e-27 95.0 0.3 4.2e-21 75.1 0.0 3.2 3 0 0 3 3 3 2 Calpain large subunit, domain III Arm PF00514.18 CBZ25470.1 - 1e-08 34.6 1.5 0.49 10.3 0.1 5.9 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat CDC14 PF08045.6 CBZ25470.1 - 0.0042 16.2 0.0 0.08 12.0 0.0 2.4 1 1 0 2 2 2 1 Cell division control protein 14, SIN component HEAT_2 PF13646.1 CBZ25470.1 - 0.0058 16.8 5.1 0.016 15.4 0.6 3.4 2 1 2 4 4 4 2 HEAT repeats PepSY_2 PF13670.1 CBZ25471.1 - 0.035 13.9 0.1 0.066 13.1 0.1 1.4 1 1 0 1 1 1 0 Peptidase propeptide and YPEB domain Nol1_Nop2_Fmu PF01189.12 CBZ25472.1 - 1.9e-24 86.5 0.0 4.7e-15 55.7 0.0 3.1 2 1 0 2 2 2 2 NOL1/NOP2/sun family WW PF00397.21 CBZ25473.1 - 1.8e-09 37.2 0.2 5e-09 35.8 0.2 1.8 1 0 0 1 1 1 1 WW domain XRN_N PF03159.13 CBZ25474.1 - 5.3e-63 212.5 0.0 2.7e-31 108.7 0.0 2.1 2 0 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus zf-RanBP PF00641.13 CBZ25474.1 - 2.9e-06 26.2 1.7 5.9e-06 25.2 1.2 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others UDPGP PF01704.13 CBZ25475.1 - 1e-07 30.8 0.0 1.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Golgin_A5 PF09787.4 CBZ25476.1 - 0.0052 15.3 0.1 0.0052 15.3 0.0 1.9 2 0 0 2 2 2 1 Golgin subfamily A member 5 Striatin PF08232.7 CBZ25477.1 - 0.031 14.5 0.9 0.031 14.5 0.7 1.6 2 0 0 2 2 2 0 Striatin family Cast PF10174.4 CBZ25479.1 - 0.00067 17.8 1.7 0.13 10.2 0.0 2.1 2 0 0 2 2 2 2 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.6 CBZ25479.1 - 0.00089 19.1 9.5 0.012 15.4 1.0 2.8 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) SlyX PF04102.7 CBZ25479.1 - 0.031 14.6 2.7 7.3 7.0 0.2 2.8 2 0 0 2 2 2 0 SlyX DUF904 PF06005.7 CBZ25479.1 - 0.11 12.8 3.8 0.73 10.1 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Atg14 PF10186.4 CBZ25479.1 - 0.17 10.7 3.7 0.57 9.0 2.5 1.8 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CBZ25479.1 - 0.24 10.9 0.9 3.9 7.0 0.0 2.2 2 0 0 2 2 2 0 IncA protein Sugarporin_N PF11471.3 CBZ25479.1 - 0.4 10.3 3.6 0.35 10.5 0.8 2.2 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF4200 PF13863.1 CBZ25479.1 - 0.47 10.4 8.0 0.38 10.7 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.3 CBZ25479.1 - 0.71 9.7 8.8 0.56 10.0 0.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 CBZ25479.1 - 6.7 6.2 7.8 0.77 9.2 0.5 2.4 2 0 0 2 2 2 0 Septum formation initiator Motile_Sperm PF00635.21 CBZ25480.1 - 2.2e-10 40.1 0.0 4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Histone PF00125.19 CBZ25481.1 - 1.2e-15 57.3 0.8 1.7e-15 56.8 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DNA_photolyase PF00875.13 CBZ25481.1 - 0.0073 16.0 0.1 0.0085 15.8 0.1 1.0 1 0 0 1 1 1 1 DNA photolyase CBFD_NFYB_HMF PF00808.18 CBZ25481.1 - 0.047 13.7 0.2 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ArsA_ATPase PF02374.10 CBZ25481.1 - 0.087 11.8 0.2 0.093 11.7 0.1 1.0 1 0 0 1 1 1 0 Anion-transporting ATPase Ribosomal_L28 PF00830.14 CBZ25481.1 - 2.2 8.1 4.8 8.5 6.2 3.3 2.0 1 1 0 1 1 1 0 Ribosomal L28 family DUF4661 PF15576.1 CBZ25482.1 - 0.0068 16.0 0.3 0.0068 16.0 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4661) TPR_11 PF13414.1 CBZ25483.1 - 2.3e-09 36.7 2.5 0.0021 17.6 0.0 4.8 4 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 CBZ25483.1 - 4.2e-08 32.4 3.7 0.076 12.9 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ25483.1 - 4.8e-05 23.6 18.1 1.2 9.9 0.0 7.7 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ25483.1 - 9.3e-05 22.3 0.0 3 8.2 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ25483.1 - 0.00067 19.1 0.0 0.5 10.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ25483.1 - 0.00089 19.8 7.8 0.03 14.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ25483.1 - 0.059 13.1 0.0 16 5.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat GNAT_acetyltr_2 PF13718.1 CBZ25484.1 - 1.8e-70 236.2 0.0 1.1e-69 233.7 0.0 2.1 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CBZ25484.1 - 1.1e-59 201.0 0.0 3.8e-59 199.2 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 CBZ25484.1 - 4.3e-35 119.2 0.3 1.3e-34 117.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CBZ25484.1 - 3.2e-16 59.2 0.0 1.1e-15 57.5 0.0 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 CBZ25484.1 - 0.057 13.5 0.0 0.22 11.7 0.0 2.0 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Oscp1 PF10188.4 CBZ25485.1 - 1.8e-60 203.7 0.2 2.3e-60 203.3 0.1 1.1 1 0 0 1 1 1 1 Organic solute transport protein 1 Sterol-sensing PF12349.3 CBZ25485.1 - 0.058 12.8 0.9 0.11 12.0 0.6 1.4 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation eIF2A PF08662.6 CBZ25488.1 - 2.5e-13 50.1 0.0 6.9e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A DUF3846 PF12957.2 CBZ25488.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) DUF2252 PF10009.4 CBZ25488.1 - 2.3 7.0 7.3 3.6 6.3 5.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Methyltransf_32 PF13679.1 CBZ25490.1 - 1.2e-13 50.9 0.2 3.3e-07 30.0 0.1 2.5 2 0 0 2 2 2 2 Methyltransferase domain CTP_transf_2 PF01467.21 CBZ25494.1 - 1.8e-19 70.3 0.0 2.4e-19 69.9 0.0 1.3 1 1 0 1 1 1 1 Cytidylyltransferase Cyt-b5 PF00173.23 CBZ25495.1 - 2.1e-16 59.4 0.0 3.7e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Xol-1_N PF09108.5 CBZ25495.1 - 0.08 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Switch protein XOL-1, N-terminal DUF4178 PF13785.1 CBZ25495.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4178) ALO PF04030.9 CBZ25496.1 - 2.5e-70 237.0 2.3 5.3e-67 226.1 0.2 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CBZ25496.1 - 9.9e-21 73.6 0.7 1.6e-20 72.9 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain SDA1 PF05285.7 CBZ25497.1 - 6.2e-94 314.8 60.2 4.6e-93 312.0 38.6 3.0 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 CBZ25497.1 - 5.4e-16 58.6 0.1 1.4e-15 57.2 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain IQ PF00612.22 CBZ25499.1 - 1.2e-10 40.0 53.5 0.012 15.1 1.4 7.8 7 0 0 7 7 7 6 IQ calmodulin-binding motif Inositol_P PF00459.20 CBZ25500.1 - 2.7e-51 174.4 0.1 3.2e-51 174.2 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_C65 PF10275.4 CBZ25501.1 - 1e-57 195.2 0.0 1.2e-57 195.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 CBZ25501.1 - 4.8e-06 27.1 0.4 0.0046 17.5 0.3 2.7 2 1 0 2 2 2 1 OTU-like cysteine protease zf-ZPR1 PF03367.8 CBZ25502.1 - 1.5e-105 349.3 0.0 2.3e-54 182.9 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DUF2387 PF09526.5 CBZ25502.1 - 0.2 11.6 0.1 0.2 11.6 0.1 3.5 3 0 0 3 3 3 0 Probable metal-binding protein (DUF2387) LLC1 PF14945.1 CBZ25503.1 - 0.66 10.2 3.8 5.4 7.3 0.0 2.8 1 1 1 3 3 3 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DltD_M PF04918.7 CBZ25503.1 - 0.85 9.7 6.9 1.7 8.8 4.7 1.6 1 1 0 1 1 1 0 DltD central region MFS_1 PF07690.11 CBZ25504.1 - 2.8e-23 82.2 46.6 3.2e-21 75.4 29.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ion_trans PF00520.26 CBZ25505.1 - 3.4e-62 209.2 55.6 1.5e-25 89.5 5.2 4.6 5 0 0 5 5 5 4 Ion transport protein RabGAP-TBC PF00566.13 CBZ25506.1 - 5.8e-17 61.8 0.4 1.1e-16 61.0 0.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ferrochelatase PF00762.14 CBZ25507.1 - 8.2e-69 231.9 0.1 7.4e-54 182.8 0.0 2.1 2 0 0 2 2 2 2 Ferrochelatase PPR_2 PF13041.1 CBZ25509.1 - 4.9e-48 160.9 13.1 5.5e-08 32.6 0.0 13.5 9 4 6 15 15 15 10 PPR repeat family PPR PF01535.15 CBZ25509.1 - 1.4e-39 131.3 23.0 0.00035 20.3 0.0 17.2 19 0 0 19 19 19 10 PPR repeat PPR_3 PF13812.1 CBZ25509.1 - 3e-33 111.2 15.1 0.29 11.5 0.0 18.8 20 1 0 20 20 20 8 Pentatricopeptide repeat domain PPR_1 PF12854.2 CBZ25509.1 - 3e-15 55.3 15.4 0.064 12.7 0.0 11.8 13 0 0 13 13 13 4 PPR repeat TPR_14 PF13428.1 CBZ25509.1 - 2e-05 24.8 4.9 3 8.7 0.2 7.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ25509.1 - 2.6e-05 24.7 0.2 0.13 12.9 0.3 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat RNA_pol_Rpb4 PF03874.11 CBZ25509.1 - 0.00063 19.7 0.0 1 9.3 0.0 3.8 4 0 0 4 4 4 1 RNA polymerase Rpb4 TPR_12 PF13424.1 CBZ25509.1 - 0.00069 19.5 3.5 5.1 7.1 0.1 5.5 5 1 0 6 6 6 1 Tetratricopeptide repeat ECSIT PF06239.6 CBZ25509.1 - 0.01 14.7 0.0 1.4 7.7 0.0 3.5 2 1 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway AHS1 PF02682.11 CBZ25509.1 - 0.047 13.1 0.0 4.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Allophanate hydrolase subunit 1 GHMP_kinases_N PF00288.21 CBZ25510.1 - 6.6e-07 29.3 2.3 1.8e-06 27.9 1.5 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBZ25510.1 - 0.094 12.9 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 GHMP kinases C terminal RRM_1 PF00076.17 CBZ25511.1 - 7.2e-07 28.7 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ25511.1 - 1.5e-06 27.9 0.1 3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ25511.1 - 0.0033 17.3 0.0 0.0086 16.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 CBZ25512.1 - 5.5e-20 71.3 50.7 7.2e-20 70.9 34.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ25512.1 - 1.9e-09 36.6 17.1 1.9e-09 36.6 11.8 2.5 1 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 CBZ25512.1 - 3.2e-06 25.5 19.6 0.00068 17.8 1.8 3.5 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family zf-C2HC_2 PF13913.1 CBZ25515.1 - 6.3e-40 134.0 65.7 1.5e-09 37.3 1.7 9.4 9 2 2 11 11 11 6 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.1 CBZ25515.1 - 9.4e-17 59.6 46.7 3e-05 23.0 1.1 9.1 9 0 0 9 9 9 5 zinc-ribbon domain DZR PF12773.2 CBZ25515.1 - 3.9e-14 52.2 62.0 6.3e-11 41.9 7.7 8.7 7 2 0 7 7 7 3 Double zinc ribbon zinc_ribbon_2 PF13240.1 CBZ25515.1 - 2.5e-10 39.5 46.7 0.0029 17.0 1.1 8.8 8 0 0 8 8 8 4 zinc-ribbon domain NOB1_Zn_bind PF08772.6 CBZ25515.1 - 0.0003 20.5 27.9 0.0065 16.2 0.3 5.7 4 1 1 5 5 5 3 Nin one binding (NOB1) Zn-ribbon like zinc-ribbons_6 PF07191.7 CBZ25515.1 - 0.01 15.6 0.6 0.01 15.6 0.4 8.0 9 1 0 9 9 9 2 zinc-ribbons Cript PF10235.4 CBZ25515.1 - 4.8 7.5 25.1 6.7 7.1 0.9 5.8 5 1 1 6 6 6 0 Microtubule-associated protein CRIPT Rad50_zn_hook PF04423.9 CBZ25515.1 - 9.7 5.7 20.5 1.8 8.0 0.2 5.4 6 0 0 6 6 6 0 Rad50 zinc hook motif 3Beta_HSD PF01073.14 CBZ25516.1 - 1.9e-10 39.9 0.0 2.7e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CBZ25516.1 - 1.8e-07 31.3 0.0 3.2e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 CBZ25516.1 - 1.9e-05 24.9 0.0 5e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 CBZ25516.1 - 0.00017 20.5 0.0 0.13 11.1 0.0 3.1 2 1 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 CBZ25516.1 - 0.0013 18.7 0.0 0.0033 17.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 CBZ25516.1 - 0.0019 17.4 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 CBZ25516.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 CBZ25516.1 - 0.039 13.3 0.0 0.086 12.2 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.5 CBZ25516.1 - 0.084 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 KR domain Glyco_hydro_31 PF01055.21 CBZ25517.1 - 5.1e-148 493.5 1.2 6.7e-148 493.1 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CBZ25517.1 - 8.9e-18 63.9 0.1 3.6e-17 61.9 0.1 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Peptidase_C21 PF05381.7 CBZ25518.1 - 0.17 12.0 0.9 0.67 10.0 0.1 2.2 2 0 0 2 2 2 0 Tymovirus endopeptidase DUF726 PF05277.7 CBZ25519.1 - 4.5e-53 180.3 22.9 5.5e-51 173.4 0.0 3.2 2 1 0 2 2 2 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 CBZ25519.1 - 0.00057 19.8 0.3 0.0027 17.6 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family VIT1 PF01988.14 CBZ25519.1 - 0.0044 16.5 6.9 0.0044 16.5 4.8 1.8 1 1 1 2 2 2 1 VIT family Abhydrolase_5 PF12695.2 CBZ25519.1 - 0.025 14.3 3.5 0.078 12.7 0.0 2.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family MHC2-interact PF09307.5 CBZ25519.1 - 0.08 12.7 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 CLIP, MHC2 interacting VirJ PF06057.6 CBZ25519.1 - 0.12 12.1 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) DUF21 PF01595.15 CBZ25521.1 - 6.2e-28 97.3 1.5 1.2e-27 96.3 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CBZ25521.1 - 1.1e-08 34.6 0.8 0.00018 21.2 0.0 3.8 4 0 0 4 4 4 2 CBS domain cNMP_binding PF00027.24 CBZ25521.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DUF21 PF01595.15 CBZ25522.1 - 9.5e-35 119.5 0.1 1.7e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CBZ25522.1 - 0.0025 17.5 0.2 4.8 7.0 0.0 3.3 3 0 0 3 3 3 2 CBS domain Metallophos PF00149.23 CBZ25523.1 - 8.7e-39 132.9 0.2 1.3e-38 132.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 CBZ25523.1 - 8.2e-24 83.4 1.2 1.3e-23 82.7 0.1 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 CBZ25523.1 - 7.4e-20 70.3 4.1 1.9e-14 53.0 0.6 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBZ25523.1 - 5.1e-17 60.6 2.9 5.5e-05 22.5 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ25523.1 - 1.4e-14 52.7 4.3 0.00038 20.1 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ25523.1 - 3.6e-06 26.7 0.4 0.00016 21.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ25523.1 - 7.8e-06 25.3 2.5 0.53 10.1 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ25523.1 - 7.4e-05 23.2 3.7 0.0018 18.8 1.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ25523.1 - 0.00014 22.1 0.9 0.067 13.8 0.1 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ25523.1 - 0.00051 20.3 0.8 0.0067 16.7 0.5 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ25523.1 - 0.0013 18.6 2.5 0.084 12.8 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Paf67 PF10255.4 CBZ25523.1 - 0.068 12.0 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_9 PF13371.1 CBZ25523.1 - 0.075 12.8 0.2 2.4 8.0 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ25523.1 - 0.092 12.5 0.1 24 5.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ25523.1 - 0.17 12.4 1.6 3.2 8.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ25523.1 - 0.47 10.6 4.5 11 6.1 0.2 2.6 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Lipase_3 PF01764.20 CBZ25524.1 - 6.7e-13 48.4 0.0 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CBZ25524.1 - 0.00022 21.1 0.4 0.00082 19.3 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ25524.1 - 0.004 16.9 0.0 0.0095 15.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CBZ25524.1 - 0.18 11.3 0.3 0.33 10.5 0.2 1.3 1 0 0 1 1 1 0 PGAP1-like protein RRM_1 PF00076.17 CBZ25525.1 - 3.7e-28 96.9 0.0 7e-17 60.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ25525.1 - 2.2e-23 81.9 0.0 1.8e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ25525.1 - 1.6e-13 50.2 0.0 1e-08 34.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 CBZ25525.1 - 0.0018 17.9 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Calcipressin Nup35_RRM_2 PF14605.1 CBZ25525.1 - 0.0064 16.2 0.0 0.67 9.7 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBZ25525.1 - 0.0074 16.0 0.0 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Limkain b1 RRM_1 PF00076.17 CBZ25526.1 - 2.9e-28 97.2 0.0 7e-17 60.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ25526.1 - 2.1e-23 82.0 0.0 1.8e-11 43.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ25526.1 - 2.4e-13 49.7 0.0 1e-08 34.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 CBZ25526.1 - 0.0019 17.8 0.0 0.016 14.7 0.0 2.1 2 0 0 2 2 2 1 Calcipressin Nup35_RRM_2 PF14605.1 CBZ25526.1 - 0.0058 16.3 0.0 0.67 9.7 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBZ25526.1 - 0.0074 16.0 0.0 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Limkain b1 RRM_1 PF00076.17 CBZ25527.1 - 7.2e-31 105.6 0.0 1e-18 66.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ25527.1 - 1.2e-20 73.2 0.1 1e-10 41.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ25527.1 - 7.4e-11 41.7 0.0 6e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ25527.1 - 0.0015 18.2 0.0 0.43 10.3 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Amino_oxidase PF01593.19 CBZ25528.1 - 4e-10 39.3 0.0 0.00035 19.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CBZ25528.1 - 4.4e-09 36.2 1.9 9.8e-09 35.1 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CBZ25528.1 - 0.0015 18.3 0.6 0.018 14.8 0.1 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CBZ25528.1 - 0.0022 18.0 0.0 0.0055 16.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBZ25528.1 - 0.0093 14.9 0.1 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CBZ25528.1 - 0.055 13.3 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1651 PF07864.6 CBZ25528.1 - 0.13 12.3 0.2 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1651) HI0933_like PF03486.9 CBZ25528.1 - 0.22 9.9 0.1 0.34 9.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.16 CBZ25528.1 - 0.36 10.6 1.6 0.67 9.7 0.1 2.3 3 0 0 3 3 3 0 ThiF family Aha1_N PF09229.6 CBZ25529.1 - 2.6e-32 111.5 0.7 3.6e-32 111.0 0.5 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CBZ25529.1 - 9.6e-19 67.7 0.0 3.1e-18 66.0 0.0 1.8 2 1 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Ribosomal_60s PF00428.14 CBZ25529.1 - 0.047 14.0 1.0 0.047 14.0 0.7 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein RRM_1 PF00076.17 CBZ25530.1 - 5.3e-12 45.1 0.0 8.4e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ25530.1 - 8e-12 44.9 0.0 1.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ25530.1 - 2.2e-06 27.4 0.0 5.1e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vfa1 PF08432.5 CBZ25530.1 - 0.94 9.4 9.6 1.3 8.9 6.7 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Metal_resist PF13801.1 CBZ25530.1 - 4.6 7.2 13.3 0.49 10.3 0.1 3.0 3 1 0 3 3 3 0 Heavy-metal resistance Ribosomal_L30 PF00327.15 CBZ25531.1 - 0.0027 17.2 0.0 0.0059 16.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DICT PF10069.4 CBZ25534.1 - 0.052 13.0 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Sensory domain found in DIguanylate Cyclases & Two-component systems Pkinase PF00069.20 CBZ25535.1 - 5.6e-55 186.2 0.0 6.6e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25535.1 - 2.2e-23 82.6 0.0 4e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ25535.1 - 0.0014 18.4 0.2 0.0079 15.9 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBZ25535.1 - 0.0031 17.1 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 CBZ25535.1 - 0.071 12.1 0.0 0.15 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_int_SAM_1 PF02899.12 CBZ25536.1 - 1.4 9.1 4.1 5.6 7.1 0.1 3.7 5 0 0 5 5 5 0 Phage integrase, N-terminal SAM-like domain CoaE PF01121.15 CBZ25537.1 - 3.5e-22 78.6 0.5 1.2e-06 28.1 0.3 4.1 4 0 0 4 4 4 4 Dephospho-CoA kinase AAA_18 PF13238.1 CBZ25537.1 - 0.041 14.1 0.2 0.46 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 CBZ25537.1 - 0.14 11.5 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RRM_6 PF14259.1 CBZ25538.1 - 2.6e-05 24.1 0.0 6.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ25538.1 - 0.13 11.9 0.0 0.51 9.9 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4379 PF14311.1 CBZ25540.1 - 2.3e-18 65.7 11.0 2.7e-11 43.0 0.6 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF4379) SprT-like PF10263.4 CBZ25540.1 - 0.0049 16.5 5.4 0.78 9.3 0.4 2.7 2 1 1 3 3 3 2 SprT-like family Elf1 PF05129.8 CBZ25540.1 - 0.0051 16.4 1.4 1.2 8.8 0.1 3.0 3 0 0 3 3 3 1 Transcription elongation factor Elf1 like zf-ZPR1 PF03367.8 CBZ25540.1 - 0.011 14.8 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 ZPR1 zinc-finger domain Zn_Tnp_IS1595 PF12760.2 CBZ25540.1 - 0.12 12.1 9.2 2 8.2 1.6 3.5 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 CBZ25540.1 - 0.17 11.8 5.5 9.6 6.2 0.3 3.3 3 0 0 3 3 3 0 Zinc ribbon domain DUF2296 PF10058.4 CBZ25540.1 - 0.21 11.3 2.7 22 4.9 0.2 3.1 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_ribbon_recom PF13408.1 CBZ25540.1 - 0.69 10.2 6.7 6.8 7.0 1.3 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C4_ClpX PF06689.8 CBZ25540.1 - 0.84 9.1 3.5 1.4 8.5 0.5 2.4 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-NADH-PPase PF09297.6 CBZ25540.1 - 1.4 8.5 10.2 0.4 10.2 0.4 3.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.1 CBZ25540.1 - 1.9 8.1 9.9 4.5 6.8 0.0 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_3 PF13920.1 CBZ25540.1 - 4.8 6.9 7.1 1.1 9.0 0.2 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DnaJ PF00226.26 CBZ25541.1 - 1.2e-16 60.1 0.0 2.1e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF446 PF04287.7 CBZ25541.1 - 0.056 13.2 0.1 0.099 12.4 0.1 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase C DUF4475 PF14753.1 CBZ25542.1 - 1.1e-15 57.7 11.7 4.5e-13 49.1 1.4 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF4475) NOB1_Zn_bind PF08772.6 CBZ25542.1 - 0.011 15.6 1.0 0.011 15.6 0.7 2.7 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like DUF2616 PF11077.3 CBZ25542.1 - 0.12 11.8 4.8 0.3 10.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) stn_TNFRSF12A PF12191.3 CBZ25542.1 - 0.34 10.9 7.5 0.81 9.7 0.1 2.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Cript PF10235.4 CBZ25542.1 - 0.59 10.5 0.1 0.59 10.5 0.0 3.2 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT ATP12 PF07542.6 CBZ25543.1 - 3.4e-27 94.8 0.0 5.7e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Peptidase_C13 PF01650.13 CBZ25544.1 - 9.6e-40 136.4 0.1 1.3e-39 136.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family TTL PF03133.10 CBZ25545.1 - 5.7e-76 255.2 0.0 7.8e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ25545.1 - 0.00019 20.3 0.0 0.0079 15.0 0.0 2.8 3 0 0 3 3 3 1 YheC/D like ATP-grasp DUF3884 PF13024.1 CBZ25545.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) Nuc_sug_transp PF04142.10 CBZ25548.1 - 6.1e-59 199.0 5.5 6.1e-59 199.0 3.8 2.2 2 1 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 CBZ25548.1 - 1.5e-07 31.1 2.0 1.5e-07 31.1 1.4 3.3 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 CBZ25548.1 - 4.6e-07 29.9 4.7 4.6e-07 29.9 3.2 3.0 3 0 0 3 3 3 1 EamA-like transporter family EmrE PF13536.1 CBZ25548.1 - 0.00016 21.8 3.8 0.00016 21.8 2.7 2.9 3 0 0 3 3 3 1 Multidrug resistance efflux transporter PAP2 PF01569.16 CBZ25551.1 - 6.1e-15 55.0 0.5 9.2e-15 54.4 0.3 1.2 1 0 0 1 1 1 1 PAP2 superfamily DUF2407_C PF13373.1 CBZ25551.1 - 0.059 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain Peptidase_M50B PF13398.1 CBZ25551.1 - 0.082 12.2 0.4 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 Peptidase M50B-like PAP2 PF01569.16 CBZ25552.1 - 1.8e-17 63.2 4.9 1.8e-17 63.2 3.4 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CBZ25552.1 - 0.018 14.6 1.9 0.099 12.1 1.3 2.1 1 1 0 1 1 1 0 PAP2 superfamily Peptidase_S10 PF00450.17 CBZ25553.1 - 9.1e-109 364.3 0.3 1.1e-108 364.0 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CBZ25553.1 - 0.0005 20.0 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ubiquitin_2 PF14560.1 CBZ25554.1 - 2e-23 82.4 0.0 3.6e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.20 CBZ25554.1 - 1.6e-22 78.9 0.4 3.8e-22 77.7 0.2 1.7 2 0 0 2 2 2 1 CAP-Gly domain ubiquitin PF00240.18 CBZ25554.1 - 0.007 15.7 0.0 0.046 13.1 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin family WD40 PF00400.27 CBZ25555.1 - 4.1e-55 181.8 22.0 1.2e-10 40.8 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBZ25555.1 - 0.0024 16.1 2.4 0.5 8.4 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 IncA PF04156.9 CBZ25555.1 - 0.096 12.2 7.8 0.16 11.5 5.4 1.3 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 CBZ25555.1 - 1.3 6.7 2.6 1.8 6.3 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 CBZ25555.1 - 1.4 8.7 20.5 2.5 7.9 14.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CDC37_N PF03234.9 CBZ25555.1 - 5.3 7.3 7.3 8.6 6.6 5.0 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding UDG PF03167.14 CBZ25556.1 - 9.2e-22 77.1 0.0 1.4e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily BTB_2 PF02214.17 CBZ25557.1 - 1.7e-13 50.5 0.0 2.7e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PPR_2 PF13041.1 CBZ25558.1 - 0.0035 17.2 0.0 1.1 9.3 0.0 3.1 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.1 CBZ25558.1 - 0.04 14.2 2.4 38 4.9 0.0 4.4 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR_1 PF12854.2 CBZ25558.1 - 0.11 12.0 0.1 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 PPR repeat PPR PF01535.15 CBZ25558.1 - 0.88 9.6 2.6 9.1 6.5 0.0 3.2 5 0 0 5 5 5 0 PPR repeat Aconitase PF00330.15 CBZ25559.1 - 1.7e-141 471.9 0.0 2.4e-141 471.4 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CBZ25559.1 - 5e-42 143.1 0.0 1.2e-41 141.8 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain CASP_C PF08172.7 CBZ25560.1 - 0.00016 20.7 7.8 0.00016 20.7 5.4 2.1 2 0 0 2 2 2 1 CASP C terminal DUF4482 PF14818.1 CBZ25560.1 - 0.019 15.5 3.5 0.019 15.5 2.4 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4482) DUF4066 PF13278.1 CBZ25560.1 - 0.3 10.3 3.4 0.72 9.1 2.3 1.6 1 0 0 1 1 1 0 Putative amidotransferase DUF4391 PF14335.1 CBZ25560.1 - 1.4 8.3 4.8 7.1 5.9 1.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4391) Mnd1 PF03962.10 CBZ25560.1 - 2.1 7.9 29.7 0.69 9.5 1.7 3.2 3 0 0 3 3 3 0 Mnd1 family LemA PF04011.7 CBZ25560.1 - 3 6.8 11.1 0.052 12.6 2.6 1.7 2 0 0 2 2 2 0 LemA family Lectin_N PF03954.9 CBZ25560.1 - 4.3 6.7 5.8 4.2 6.7 0.0 3.0 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain EMP24_GP25L PF01105.19 CBZ25560.1 - 5.6 6.6 7.4 0.54 9.9 0.6 2.2 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD TBCC PF07986.7 CBZ25561.1 - 1.6e-33 114.6 0.1 2.3e-33 114.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C FOP_dimer PF09398.5 CBZ25561.1 - 0.00044 20.1 0.0 0.00078 19.3 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain CAP_C PF08603.6 CBZ25561.1 - 0.18 11.1 0.2 0.33 10.2 0.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Ring_hydroxyl_A PF00848.14 CBZ25563.1 - 0.034 13.7 0.2 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 Ring hydroxylating alpha subunit (catalytic domain) FAM176 PF14851.1 CBZ25563.1 - 0.2 11.3 2.2 0.19 11.3 0.4 1.7 1 1 0 1 1 1 0 FAM176 family Atrophin-1 PF03154.10 CBZ25563.1 - 0.66 8.0 3.7 0.7 7.9 2.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF4337 PF14235.1 CBZ25563.1 - 8.7 6.1 6.7 15 5.4 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) V-ATPase_C PF03223.10 CBZ25564.1 - 5.2e-91 305.3 0.1 6.4e-91 305.0 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C PapD-like PF14874.1 CBZ25565.1 - 5.6e-10 39.0 5.0 0.0065 16.4 0.1 4.8 4 0 0 4 4 4 3 Flagellar-associated PapD-like Motile_Sperm PF00635.21 CBZ25565.1 - 1.8e-05 24.3 0.3 0.0041 16.7 0.0 4.0 4 0 0 4 4 4 1 MSP (Major sperm protein) domain PapD_N PF00345.15 CBZ25565.1 - 0.0003 20.5 2.0 2.2 8.0 0.0 4.8 6 1 0 6 6 6 2 Pili and flagellar-assembly chaperone, PapD N-terminal domain MYCBPAP PF14646.1 CBZ25565.1 - 0.05 12.3 0.0 0.47 9.1 0.0 2.3 2 0 0 2 2 2 0 MYCBP-associated protein family ECH PF00378.15 CBZ25566.1 - 1e-32 113.1 1.4 2.5e-30 105.4 0.3 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family ATP_Ca_trans_C PF12424.3 CBZ25566.1 - 0.06 13.7 0.1 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Plasma membrane calcium transporter ATPase C terminal RRM_1 PF00076.17 CBZ25567.1 - 3.9e-17 61.6 0.0 8.2e-17 60.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ25567.1 - 5.5e-12 45.4 0.0 9.8e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ25567.1 - 4.5e-10 39.2 0.0 8.6e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ25567.1 - 0.049 13.3 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FYVE PF01363.16 CBZ25569.1 - 1.1e-19 70.0 8.6 1.1e-19 70.0 5.9 4.7 3 2 1 4 4 4 1 FYVE zinc finger zf-RanBP PF00641.13 CBZ25569.1 - 8.2e-17 60.0 62.3 1.4e-07 30.4 1.2 6.8 7 0 0 7 7 7 5 Zn-finger in Ran binding protein and others DZR PF12773.2 CBZ25569.1 - 2e-05 24.3 46.1 0.038 13.8 5.1 5.7 3 2 3 6 6 6 5 Double zinc ribbon Peptidase_M41 PF01434.13 CBZ25570.1 - 4.5e-48 163.5 1.9 6.8e-48 162.9 1.3 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBZ25570.1 - 1.3e-39 135.4 0.0 2.4e-39 134.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ25570.1 - 9.4e-06 25.7 1.0 0.00042 20.3 0.6 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ25570.1 - 9.8e-05 22.5 0.1 0.0016 18.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ25570.1 - 0.00035 20.2 0.1 0.0016 18.1 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CBZ25570.1 - 0.00091 18.9 0.2 0.0062 16.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBZ25570.1 - 0.0013 18.6 0.2 0.0065 16.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CBZ25570.1 - 0.0014 19.4 0.4 0.004 17.9 0.1 2.0 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CBZ25570.1 - 0.0038 16.6 1.7 0.048 13.0 0.2 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CBZ25570.1 - 0.0077 15.2 0.9 0.044 12.8 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CBZ25570.1 - 0.01 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CBZ25570.1 - 0.016 14.7 0.1 0.064 12.7 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain Peptidase_M50B PF13398.1 CBZ25570.1 - 0.018 14.3 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like IstB_IS21 PF01695.12 CBZ25570.1 - 0.019 14.4 0.2 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CBZ25570.1 - 0.02 13.9 0.2 0.26 10.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 CBZ25570.1 - 0.036 13.7 0.2 0.73 9.4 0.1 2.7 3 0 0 3 3 3 0 NACHT domain DUF2075 PF09848.4 CBZ25570.1 - 0.05 12.5 0.1 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 CBZ25570.1 - 0.051 12.2 0.0 0.12 11.0 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus KaiC PF06745.8 CBZ25570.1 - 0.085 11.9 0.1 0.23 10.5 0.0 1.7 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.10 CBZ25570.1 - 0.14 11.8 0.1 0.83 9.3 0.0 2.1 2 0 0 2 2 2 0 NTPase Ribosomal_L1 PF00687.16 CBZ25571.1 - 5.3e-47 159.9 3.2 6.2e-47 159.7 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pkinase PF00069.20 CBZ25573.1 - 5.1e-74 248.7 0.0 5.7e-74 248.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25573.1 - 2.7e-39 134.7 0.0 3.3e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25573.1 - 1.1e-10 40.9 0.0 1.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ25573.1 - 5.8e-06 26.2 0.1 0.046 13.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBZ25573.1 - 0.0043 16.1 0.1 0.0066 15.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBZ25573.1 - 0.031 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF421 PF04239.7 CBZ25573.1 - 0.06 12.8 1.8 0.15 11.6 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF421) YukC PF10140.4 CBZ25573.1 - 0.074 11.6 0.0 0.097 11.2 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Phosducin PF02114.11 CBZ25573.1 - 0.077 11.7 0.1 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosducin Choline_kinase PF01633.15 CBZ25573.1 - 0.093 12.2 0.0 0.2 11.2 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 CBZ25573.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PA26 PF04636.8 CBZ25574.1 - 6.7e-30 104.1 1.9 1.6e-11 43.5 0.0 3.1 3 0 0 3 3 3 3 PA26 p53-induced protein (sestrin) HEAT PF02985.17 CBZ25575.1 - 7e-22 75.4 17.1 0.00087 19.1 0.0 10.7 11 0 0 11 11 11 7 HEAT repeat HEAT_2 PF13646.1 CBZ25575.1 - 6.2e-19 68.0 16.1 2.8e-06 27.4 0.0 6.9 3 2 2 7 7 7 6 HEAT repeats HEAT_EZ PF13513.1 CBZ25575.1 - 1.4e-05 25.4 13.7 0.0076 16.7 0.0 7.0 8 0 0 8 8 8 2 HEAT-like repeat Adaptin_N PF01602.15 CBZ25575.1 - 0.0023 16.3 0.3 2.2 6.5 0.1 3.5 1 1 0 5 5 5 2 Adaptin N terminal region CLASP_N PF12348.3 CBZ25575.1 - 0.0037 16.6 0.1 11 5.2 0.0 3.8 2 1 2 4 4 4 2 CLASP N terminal Leuk-A4-hydro_C PF09127.6 CBZ25575.1 - 0.064 12.8 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal Citrate_synt PF00285.16 CBZ25577.1 - 4.3e-103 344.7 0.1 8.1e-103 343.8 0.0 1.4 2 0 0 2 2 2 1 Citrate synthase Cyclin_C PF02984.14 CBZ25577.1 - 0.021 14.7 2.2 0.086 12.7 0.0 2.6 2 0 0 2 2 2 0 Cyclin, C-terminal domain Citrate_synt PF00285.16 CBZ25578.1 - 8.5e-101 337.2 0.0 1e-100 336.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Cyclin_C PF02984.14 CBZ25578.1 - 0.031 14.2 2.2 0.064 13.1 0.1 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain AAA_16 PF13191.1 CBZ25580.1 - 0.01 15.8 0.1 0.01 15.8 0.1 3.3 3 0 0 3 3 3 0 AAA ATPase domain Spc7 PF08317.6 CBZ25580.1 - 0.15 10.7 0.4 0.23 10.0 0.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 CBZ25580.1 - 0.17 11.8 0.3 0.37 10.8 0.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3827 PF12877.2 CBZ25580.1 - 0.24 9.4 0.1 0.41 8.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Tctex-1 PF03645.8 CBZ25581.1 - 3.1e-21 75.1 0.1 8.5e-21 73.7 0.0 1.6 2 0 0 2 2 2 1 Tctex-1 family AF1Q PF15017.1 CBZ25581.1 - 0.62 10.0 8.8 1.4 8.8 6.1 1.8 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator Daxx PF03344.10 CBZ25581.1 - 1.1 7.6 5.9 1.2 7.4 4.1 1.2 1 0 0 1 1 1 0 Daxx Family Cwf_Cwc_15 PF04889.7 CBZ25581.1 - 4.5 6.9 8.2 6 6.5 5.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRN9 PF10680.4 CBZ25581.1 - 4.9 6.9 5.2 1.2 8.8 0.2 2.4 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor GTP_EFTU PF00009.22 CBZ25582.1 - 7.8e-55 185.2 0.1 1.3e-54 184.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ25582.1 - 7e-20 71.0 0.3 2.9e-18 65.8 0.0 2.9 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ25582.1 - 1.1e-07 31.8 0.8 2.8e-07 30.5 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ25582.1 - 0.0023 17.8 0.0 0.0047 16.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CBZ25582.1 - 0.014 14.9 0.4 0.014 14.9 0.3 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Miro PF08477.8 CBZ25582.1 - 0.036 14.5 0.0 0.12 12.8 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein PduV-EutP PF10662.4 CBZ25582.1 - 0.049 13.1 1.1 2.7 7.4 0.8 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 CBZ25582.1 - 0.11 12.0 0.1 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-C2H2_jaz PF12171.3 CBZ25584.1 - 9.3e-08 32.0 0.3 1.8e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBZ25584.1 - 3.2e-05 23.9 0.2 5e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBZ25584.1 - 0.041 13.9 0.3 0.052 13.6 0.2 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Fer4_18 PF13746.1 CBZ25584.1 - 0.084 13.3 0.1 0.1 13.0 0.1 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain PDZ_2 PF13180.1 CBZ25585.1 - 0.004 17.0 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBZ25585.1 - 0.17 12.0 0.0 0.44 10.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) RNA_pol_Rpb5_C PF01191.14 CBZ25586.1 - 1.2e-31 108.0 0.6 2.3e-31 107.2 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CBZ25586.1 - 4.6e-13 49.4 0.0 2e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 CBZ25587.1 - 3.8e-24 84.0 0.0 6.8e-24 83.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CBZ25587.1 - 8.6e-08 32.4 0.0 0.00016 22.0 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb5, N-terminal domain Ribosomal_S8 PF00410.14 CBZ25588.1 - 1.9e-11 43.8 0.0 2.7e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 CDP-OH_P_transf PF01066.16 CBZ25589.1 - 6.7e-26 90.5 0.6 6.7e-26 90.5 0.4 3.0 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase HEAT PF02985.17 CBZ25590.1 - 8.1e-09 34.8 2.7 0.09 12.9 0.1 8.6 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 CBZ25590.1 - 0.0011 19.3 30.2 0.014 15.8 1.0 9.8 9 1 1 10 10 10 3 HEAT-like repeat Cnd1 PF12717.2 CBZ25590.1 - 0.0015 18.3 2.1 2.9 7.7 0.1 4.9 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CBZ25590.1 - 0.017 15.4 0.5 68 3.9 0.0 5.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Cnd2 PF05786.9 CBZ25590.1 - 1.7 7.0 0.4 2.4 6.5 0.3 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 WD40 PF00400.27 CBZ25591.1 - 3.4e-30 102.8 23.3 5.9e-10 38.6 0.1 12.1 13 0 0 13 13 13 5 WD domain, G-beta repeat Utp12 PF04003.7 CBZ25591.1 - 1.6e-06 27.9 0.0 4.1e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Dip2/Utp12 Family DUF1513 PF07433.6 CBZ25591.1 - 0.0029 16.5 1.0 0.39 9.5 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1513) Sorting_nexin PF03700.8 CBZ25595.1 - 0.032 14.3 0.2 0.077 13.1 0.2 1.7 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain Pro_isomerase PF00160.16 CBZ25596.1 - 5.2e-35 120.9 0.0 2.5e-33 115.4 0.0 2.2 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.17 CBZ25597.1 - 7.9e-54 181.3 1.4 1.2e-52 177.5 0.9 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBZ25597.1 - 3.6e-21 75.8 0.1 7.3e-21 74.8 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CBZ25597.1 - 2.6e-12 46.3 0.0 3.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ25597.1 - 6.1e-09 35.3 0.0 8e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ25597.1 - 3.3e-05 23.8 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBZ25597.1 - 3.4e-05 23.3 0.1 0.00064 19.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CBZ25597.1 - 0.0017 18.5 0.0 0.0035 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 CBZ25597.1 - 0.0021 17.7 0.0 0.012 15.2 0.0 2.0 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CBZ25597.1 - 0.0022 18.0 0.1 0.0035 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 CBZ25597.1 - 0.0069 15.9 0.1 0.015 14.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CBZ25597.1 - 0.0077 15.9 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 NTPase Arch_ATPase PF01637.13 CBZ25597.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase cobW PF02492.14 CBZ25597.1 - 0.016 14.6 0.1 3.2 7.1 0.0 2.3 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CBZ25597.1 - 0.024 13.8 0.1 0.045 12.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 CBZ25597.1 - 0.025 14.0 0.1 0.048 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain NACHT PF05729.7 CBZ25597.1 - 0.029 14.0 0.0 0.047 13.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 CBZ25597.1 - 0.035 13.8 0.0 0.066 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 CBZ25597.1 - 0.067 12.6 0.1 0.2 11.1 0.0 1.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CBZ25597.1 - 0.071 13.2 0.0 0.29 11.3 0.0 2.0 1 1 0 1 1 1 0 RNA helicase PRK PF00485.13 CBZ25597.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Glyco_trans_1_4 PF13692.1 CBZ25598.1 - 3.5e-09 36.9 0.0 1.6e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 T2SE_Nter PF05157.10 CBZ25598.1 - 0.055 13.5 0.4 0.84 9.7 0.0 2.9 3 1 1 4 4 4 0 Type II secretion system (T2SS), protein E, N-terminal domain PPR_2 PF13041.1 CBZ25599.1 - 0.00041 20.2 0.0 0.22 11.5 0.0 3.2 2 1 1 3 3 3 2 PPR repeat family PPR_3 PF13812.1 CBZ25599.1 - 0.0092 16.1 13.7 4.1 7.9 0.1 7.3 7 1 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 CBZ25599.1 - 0.12 12.4 0.1 19 5.5 0.0 3.5 4 0 0 4 4 4 0 PPR repeat WD40 PF00400.27 CBZ25600.1 - 6.3e-12 44.8 10.5 0.0018 18.0 0.5 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat PD40 PF07676.7 CBZ25600.1 - 0.011 15.3 0.0 0.78 9.4 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Myosin_TH1 PF06017.8 CBZ25601.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Myosin tail GAS PF13851.1 CBZ25601.1 - 5.5 6.1 15.6 0.15 11.2 1.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 CBZ25601.1 - 8.4 4.1 4.9 12 3.5 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nrap PF03813.9 CBZ25602.1 - 1.5e-68 231.3 0.0 4.4e-68 229.7 0.0 1.6 2 1 0 2 2 2 1 Nrap protein Zn-ribbon_8 PF09723.5 CBZ25603.1 - 0.025 14.5 1.9 0.19 11.7 0.5 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Mannosyl_trans2 PF04188.8 CBZ25604.1 - 2.4e-36 125.5 28.0 2.7e-22 79.2 8.2 4.1 4 0 0 4 4 4 4 Mannosyltransferase (PIG-V)) TPR_MLP1_2 PF07926.7 CBZ25606.1 - 0.11 12.2 11.2 0.023 14.4 5.5 1.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 CBZ25606.1 - 0.16 10.9 8.5 0.25 10.3 5.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CBZ25606.1 - 0.75 7.5 4.1 0.85 7.3 2.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 CBZ25606.1 - 1.9 8.5 16.2 1.6 8.8 8.4 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 CBZ25606.1 - 5.9 6.4 15.4 9.5 5.7 10.6 1.4 1 1 0 1 1 1 0 IncA protein Plasmid_RAQPRD PF09686.5 CBZ25606.1 - 6.2 6.9 7.2 4 7.5 0.6 2.7 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) UDPGP PF01704.13 CBZ25607.1 - 3.7e-88 295.8 0.0 5.5e-88 295.2 0.0 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Sigma70_ECF PF07638.6 CBZ25607.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 ECF sigma factor Mito_carr PF00153.22 CBZ25608.1 - 8.4e-19 67.0 5.0 3.4e-09 36.2 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Robl_LC7 PF03259.12 CBZ25609.1 - 9.8e-22 76.3 0.0 1.1e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain IncA PF04156.9 CBZ25610.1 - 0.0021 17.7 1.0 0.0021 17.7 0.7 3.3 4 0 0 4 4 4 2 IncA protein SlyX PF04102.7 CBZ25610.1 - 3.6 8.0 15.9 0.074 13.4 1.2 3.9 3 1 0 4 4 4 0 SlyX DUF342 PF03961.8 CBZ25610.1 - 4.7 5.5 5.5 2.4 6.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) PhoD PF09423.5 CBZ25611.1 - 1.1e-09 37.4 0.2 1.4e-08 33.7 0.2 2.5 1 1 0 1 1 1 1 PhoD-like phosphatase Hydantoinase_B PF02538.9 CBZ25612.1 - 5e-171 569.4 0.0 1.3e-168 561.5 0.0 2.1 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 CBZ25612.1 - 1.8e-86 289.8 0.7 5e-86 288.4 0.5 1.8 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CBZ25612.1 - 2.7e-49 167.0 0.7 1.1e-47 161.7 0.1 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Peptidase_M15_3 PF08291.6 CBZ25612.1 - 0.041 13.7 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Peptidase M15 DUF3157 PF11355.3 CBZ25613.1 - 0.041 13.1 0.1 0.084 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) DnaJ PF00226.26 CBZ25613.1 - 0.23 11.2 0.0 0.52 10.0 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain Peptidase_C2 PF00648.16 CBZ25614.1 - 3.7e-13 49.1 0.0 2.9e-12 46.2 0.0 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease SRP14 PF02290.10 CBZ25614.1 - 0.01 15.7 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle 14kD protein Vps16_C PF04840.7 CBZ25615.1 - 2.4e-24 85.8 0.2 3.4e-12 45.9 0.0 2.4 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.8 CBZ25615.1 - 2.3e-22 79.1 0.0 1.7e-20 72.9 0.0 2.7 2 1 0 2 2 2 2 Vps16, N-terminal region DUF169 PF02596.10 CBZ25615.1 - 0.028 13.8 0.0 0.83 8.9 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised ArCR, COG2043 Pkinase PF00069.20 CBZ25616.1 - 3.4e-72 242.7 0.0 3.9e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25616.1 - 2.1e-36 125.3 0.0 2.6e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25616.1 - 1.1e-06 27.7 0.0 2.5e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBZ25616.1 - 0.04 13.6 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CBZ25616.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PDEase_I PF00233.14 CBZ25617.1 - 3.1e-67 226.7 1.0 5.3e-67 226.0 0.0 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Ank_5 PF13857.1 CBZ25618.1 - 3.1e-24 84.4 3.7 8.3e-10 38.5 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CBZ25618.1 - 1.9e-23 81.0 0.2 1.2e-09 37.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 CBZ25618.1 - 6.4e-22 77.6 0.3 1.9e-14 53.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CBZ25618.1 - 2.2e-18 64.5 0.2 4e-06 26.5 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 CBZ25618.1 - 4.3e-17 62.1 0.4 1.5e-10 41.2 0.0 4.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Pheromone PF08015.6 CBZ25618.1 - 0.57 11.0 3.0 14 6.5 2.1 2.4 1 1 0 1 1 1 0 Fungal mating-type pheromone Nol1_Nop2_Fmu PF01189.12 CBZ25619.1 - 6.6e-26 91.3 0.0 5.6e-25 88.2 0.0 2.3 1 1 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 CBZ25619.1 - 0.00017 21.6 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 CBZ25619.1 - 0.0032 17.4 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain zf-AN1 PF01428.11 CBZ25620.1 - 1.8e-18 66.1 27.1 6.5e-10 38.7 6.6 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CBZ25620.1 - 0.00039 20.5 17.1 0.0075 16.4 1.3 2.8 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain IBR PF01485.16 CBZ25620.1 - 7.6 6.4 25.9 0.079 12.8 2.5 3.2 4 0 0 4 4 4 0 IBR domain Ras PF00071.17 CBZ25621.1 - 7.7e-52 174.9 0.0 1.9e-51 173.6 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBZ25621.1 - 1.2e-13 51.5 0.0 3e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ25621.1 - 1.4e-10 40.7 0.0 2.7e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ25621.1 - 0.00011 21.4 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ25621.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 CBZ25621.1 - 0.016 15.3 0.0 0.05 13.7 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CBZ25621.1 - 0.034 13.6 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF1327 PF07041.6 CBZ25621.1 - 0.054 13.4 0.1 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) ABC_tran PF00005.22 CBZ25621.1 - 0.069 13.4 0.1 0.097 12.9 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 CBZ25621.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CBZ25621.1 - 0.1 11.7 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 CBZ25621.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Hpr_kinase_C PF07475.7 CBZ25621.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain MSG PF02349.10 CBZ25622.1 - 0.012 15.5 3.5 0.095 12.6 2.4 2.6 1 0 0 1 1 1 0 Major surface glycoprotein zf-C3HC4_3 PF13920.1 CBZ25623.1 - 7.3e-17 60.7 11.4 1.3e-16 59.9 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ25623.1 - 4.1e-09 36.3 14.9 8.8e-09 35.2 10.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ25623.1 - 7.2e-06 25.7 13.2 1.4e-05 24.7 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBZ25623.1 - 0.013 15.1 12.0 0.029 14.1 8.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_2 PF13240.1 CBZ25623.1 - 0.093 12.2 0.5 0.21 11.1 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-P11 PF03854.9 CBZ25623.1 - 0.11 12.0 10.0 0.25 10.8 6.9 1.7 1 1 0 1 1 1 0 P-11 zinc finger SOG2 PF10428.4 CBZ25623.1 - 0.19 10.3 3.7 0.32 9.5 2.5 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein PAT1 PF09770.4 CBZ25623.1 - 0.58 8.3 9.6 0.68 8.1 6.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 CBZ25623.1 - 1.5 8.1 13.3 2.5 7.4 9.3 1.3 1 0 0 1 1 1 0 Vta1 like Pex14_N PF04695.8 CBZ25623.1 - 1.7 8.6 8.0 4.2 7.4 5.2 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Prok-RING_4 PF14447.1 CBZ25623.1 - 3.8 7.1 9.7 13 5.3 6.7 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TPR_7 PF13176.1 CBZ25624.1 - 0.066 13.0 0.1 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ25624.1 - 0.15 12.5 0.3 0.37 11.3 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Cmc1 PF08583.5 CBZ25625.1 - 0.0059 16.3 2.6 0.013 15.2 1.8 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NPV_P10 PF05531.7 CBZ25626.1 - 0.33 11.2 5.9 0.22 11.8 0.8 2.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Complex1_LYR PF05347.10 CBZ25628.1 - 1.3e-09 37.7 1.8 1.3e-09 37.7 1.3 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBZ25628.1 - 1.5e-08 34.7 3.1 3.5e-08 33.5 1.3 2.0 2 0 0 2 2 2 1 Complex1_LYR-like ProRS-C_1 PF09180.6 CBZ25629.1 - 6.4e-25 86.8 2.8 6.4e-25 86.8 1.9 2.1 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.10 CBZ25629.1 - 6.9e-18 64.6 0.1 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.20 CBZ25629.1 - 6.4e-16 58.4 0.1 1.9e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBZ25629.1 - 4.5e-15 55.3 0.0 2.2e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain ProRS-C_1 PF09180.6 CBZ25630.1 - 6.2e-25 86.9 2.8 6.2e-25 86.9 1.9 2.1 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA_edit PF04073.10 CBZ25630.1 - 4.5e-21 74.9 0.1 8.7e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2b PF00587.20 CBZ25630.1 - 9.7e-16 57.8 0.0 1.8e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBZ25630.1 - 1.7e-11 43.8 0.0 6.6e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain SET PF00856.23 CBZ25631.1 - 2.8e-08 34.2 0.0 1.4e-07 31.9 0.0 2.1 1 1 0 1 1 1 1 SET domain HTH_Tnp_1 PF01527.15 CBZ25631.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Transposase SAF PF08666.7 CBZ25631.1 - 0.12 12.7 0.0 27 5.2 0.0 2.7 2 0 0 2 2 2 0 SAF domain PIH1 PF08190.7 CBZ25632.1 - 2.2e-32 112.7 0.9 1.9e-21 76.9 0.0 4.8 3 2 1 5 5 5 3 pre-RNA processing PIH1/Nop17 MCRS_N PF13325.1 CBZ25633.1 - 0.00015 21.3 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 N-terminal region of micro-spherule protein Mito_carr PF00153.22 CBZ25634.1 - 1.2e-36 124.2 4.8 1.1e-15 57.1 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein NSs PF11073.3 CBZ25634.1 - 0.11 11.7 0.1 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Rift valley fever virus non structural protein (NSs) like DmpG_comm PF07836.6 CBZ25634.1 - 0.16 11.4 0.4 22 4.5 0.0 3.3 3 0 0 3 3 3 0 DmpG-like communication domain Mito_carr PF00153.22 CBZ25635.1 - 2.6e-35 120.0 6.0 1e-14 54.0 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DmpG_comm PF07836.6 CBZ25635.1 - 0.16 11.3 0.6 21 4.6 0.0 3.3 3 0 0 3 3 3 0 DmpG-like communication domain Acetyltransf_1 PF00583.19 CBZ25636.1 - 3.6e-10 39.7 0.1 5.6e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ25636.1 - 2.8e-05 24.1 0.1 0.0051 16.9 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBZ25636.1 - 0.003 17.6 0.3 0.023 14.8 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Phytochelatin PF05023.9 CBZ25637.1 - 6.8e-05 21.9 0.1 0.63 8.9 0.0 3.6 3 0 0 3 3 3 3 Phytochelatin synthase CTP_transf_2 PF01467.21 CBZ25638.1 - 4e-11 43.2 0.0 6.7e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase CDP-OH_P_transf PF01066.16 CBZ25638.1 - 5e-05 23.5 2.4 5e-05 23.5 1.6 3.7 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FAD_syn PF06574.7 CBZ25638.1 - 0.073 12.6 0.6 0.23 11.0 0.1 2.1 2 1 0 2 2 2 0 FAD synthetase zf-CCCH PF00642.19 CBZ25639.1 - 0.00074 19.1 9.8 0.46 10.2 0.0 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 CBZ25640.1 - 0.0017 17.9 10.1 0.031 13.9 1.4 2.7 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tropomyosin_1 PF12718.2 CBZ25641.1 - 3.7 7.3 121.4 0.11 12.3 14.1 7.9 3 1 5 8 8 8 0 Tropomyosin like HSP70 PF00012.15 CBZ25642.1 - 3.7e-107 358.7 1.6 9.3e-101 337.5 0.0 2.9 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 CBZ25642.1 - 0.00048 18.8 0.5 0.005 15.4 0.0 2.7 2 1 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CBZ25642.1 - 0.0016 18.0 0.0 0.0033 17.0 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain E1_dh PF00676.15 CBZ25643.1 - 6.2e-101 337.0 0.4 7.2e-101 336.8 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CBZ25643.1 - 0.00039 19.4 0.4 0.0016 17.3 0.0 1.8 1 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase RRF PF01765.14 CBZ25643.1 - 0.14 11.6 7.0 0.21 11.0 4.9 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Ribosomal_L34e PF01199.13 CBZ25645.1 - 1.3e-27 95.8 4.0 1.3e-27 95.8 2.8 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e NARP1 PF12569.3 CBZ25645.1 - 0.38 9.4 8.9 0.42 9.3 6.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PUF PF00806.14 CBZ25647.1 - 1e-45 150.6 0.4 1.1e-05 24.6 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DnaJ PF00226.26 CBZ25648.1 - 7.2e-17 60.8 2.1 7.5e-17 60.8 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain CAF-1_p150 PF11600.3 CBZ25648.1 - 0.12 11.6 47.0 0.23 10.7 12.4 3.8 3 0 0 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal EF-hand_7 PF13499.1 CBZ25649.1 - 4e-12 46.1 1.4 2.3e-08 34.0 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ25649.1 - 6.7e-09 34.8 0.7 9.4e-05 21.9 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CBZ25649.1 - 2.3e-08 32.7 2.1 0.004 16.3 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBZ25649.1 - 0.00058 19.4 3.8 0.56 9.8 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBZ25649.1 - 0.00089 18.4 1.9 0.005 16.1 0.1 3.0 3 0 0 3 3 3 1 EF hand DUF3648 PF12364.3 CBZ25650.1 - 8.6e-53 178.1 2.7 8.6e-53 178.1 1.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3648) PAP_assoc PF03828.14 CBZ25650.1 - 0.74 9.8 0.9 1.7 8.6 0.6 1.5 1 0 0 1 1 1 0 Cid1 family poly A polymerase WD40 PF00400.27 CBZ25651.1 - 4.7e-07 29.4 1.2 0.0029 17.4 0.2 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat CTP_transf_2 PF01467.21 CBZ25652.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase NADH-G_4Fe-4S_3 PF10588.4 CBZ25653.1 - 5.7e-17 60.6 0.3 5.7e-17 60.6 0.2 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 CBZ25653.1 - 9.7e-13 47.7 0.1 2.4e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 CBZ25653.1 - 8.8e-08 31.7 0.2 2.3e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.1 CBZ25653.1 - 0.23 11.9 6.3 0.11 12.9 2.2 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBZ25653.1 - 2 8.7 6.8 0.72 10.1 1.7 2.5 3 0 0 3 3 3 0 4Fe-4S dicluster domain zf-C3HC4_3 PF13920.1 CBZ25653.1 - 4 7.1 9.2 15 5.3 0.0 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Fer4_7 PF12838.2 CBZ25653.1 - 5.7 7.4 11.8 1.1e+02 3.3 7.5 3.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain DnaJ PF00226.26 CBZ25654.1 - 1.8e-12 46.7 0.0 3e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 CBZ25654.1 - 8.8e-06 25.1 3.2 2.9e-05 23.4 2.2 1.8 1 1 0 1 1 1 1 CSL zinc finger E1-E2_ATPase PF00122.15 CBZ25656.1 - 1.1e-26 93.3 2.4 5.3e-26 91.0 1.8 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CBZ25656.1 - 3.7e-12 47.1 0.0 6.1e-11 43.1 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ25656.1 - 9e-09 35.7 0.0 3.6e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ25656.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 CBZ25657.1 - 8.8e-58 195.0 1.7 8.8e-58 195.0 1.2 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CBZ25657.1 - 7.3e-25 88.6 0.0 1.5e-23 84.3 0.0 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ25657.1 - 6.4e-14 52.5 0.1 2.5e-13 50.6 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBZ25657.1 - 1.5e-13 49.9 0.0 3.5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CBZ25657.1 - 8.9e-06 25.4 0.1 0.00018 21.2 0.1 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ25657.1 - 0.036 14.0 0.0 0.081 12.8 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit YrvL PF14184.1 CBZ25657.1 - 7.8 6.3 17.7 2.4 7.9 5.4 2.5 2 0 0 2 2 2 0 Regulatory protein YrvL Kinesin PF00225.18 CBZ25658.1 - 3.4e-48 164.0 0.1 6e-48 163.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 CBZ25658.1 - 0.014 15.5 0.3 0.069 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CBZ25658.1 - 0.069 13.3 0.0 0.29 11.3 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CBZ25658.1 - 0.15 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.12 CBZ25658.1 - 0.22 11.3 1.2 1.8 8.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 UAA PF08449.6 CBZ25659.1 - 1.3e-49 168.7 7.1 2.2e-49 168.0 4.9 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CBZ25659.1 - 1.6e-05 24.5 13.8 2.8e-05 23.8 3.1 2.6 2 2 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 CBZ25659.1 - 0.013 14.6 3.2 0.02 14.0 0.3 2.2 2 0 0 2 2 2 0 Nucleotide-sugar transporter EamA PF00892.15 CBZ25659.1 - 0.57 10.2 18.5 0.45 10.5 4.6 3.8 3 1 1 4 4 4 0 EamA-like transporter family DUF1056 PF06341.6 CBZ25659.1 - 1.7 8.7 5.3 5.6 7.0 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1056) BTB PF00651.26 CBZ25660.1 - 0.00022 21.1 0.0 0.00088 19.2 0.0 1.9 1 1 0 2 2 2 1 BTB/POZ domain Vhr1 PF04001.8 CBZ25661.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Transcription factor Vhr1 Inhibitor_G39P PF11417.3 CBZ25661.1 - 0.14 12.1 0.0 24 5.0 0.0 2.6 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P zf-C3HC4_3 PF13920.1 CBZ25662.1 - 1.9e-14 53.0 13.8 2.5e-14 52.6 9.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ25662.1 - 4.9e-07 29.6 17.3 7.2e-07 29.1 12.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ25662.1 - 0.0028 17.4 16.2 0.0041 16.9 11.2 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 CBZ25662.1 - 0.054 13.0 9.2 0.11 12.0 6.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 IU_nuc_hydro PF01156.14 CBZ25663.1 - 1.2e-96 323.6 1.5 1.3e-96 323.4 1.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Kinesin PF00225.18 CBZ25665.1 - 2.3e-63 213.9 0.1 4e-63 213.1 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Noc2 PF03715.8 CBZ25666.1 - 5.1e-97 324.3 1.8 8.3e-97 323.6 1.2 1.3 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.7 CBZ25666.1 - 0.0074 14.2 15.6 0.47 8.3 10.2 2.2 2 0 0 2 2 2 2 Nop14-like family Potyvirid-P3 PF13608.1 CBZ25666.1 - 0.22 10.6 5.8 0.093 11.8 1.8 2.0 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein DUF4441 PF14536.1 CBZ25666.1 - 0.24 11.3 2.6 0.73 9.8 1.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) Got1 PF04178.7 CBZ25667.1 - 1.3e-15 57.5 15.9 1.4e-15 57.3 11.0 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF872 PF05915.7 CBZ25667.1 - 0.91 9.4 3.3 0.69 9.7 0.9 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) ATP1G1_PLM_MAT8 PF02038.11 CBZ25667.1 - 2.1 7.4 5.7 0.52 9.3 0.1 2.7 2 1 1 3 3 3 0 ATP1G1/PLM/MAT8 family Rtf2 PF04641.7 CBZ25669.1 - 0.94 8.6 4.7 0.4 9.8 0.2 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger DUF4023 PF13215.1 CBZ25669.1 - 5 6.9 5.6 3.8 7.3 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4023) DnaJ PF00226.26 CBZ25671.1 - 3e-14 52.4 0.3 2.8e-13 49.3 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain TPR_12 PF13424.1 CBZ25671.1 - 0.0011 18.8 14.7 0.27 11.1 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ25671.1 - 0.061 13.2 12.7 15 5.7 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat GCS PF03074.11 CBZ25672.1 - 3.1e-165 549.7 0.2 3.9e-165 549.3 0.2 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase SNARE PF05739.14 CBZ25674.1 - 2.7e-11 42.9 1.3 2.7e-11 42.9 0.9 2.9 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.6 CBZ25674.1 - 0.013 15.9 4.0 0.044 14.1 0.7 2.9 3 1 0 3 3 3 0 Syntaxin 6, N-terminal DUF4142 PF13628.1 CBZ25674.1 - 0.025 14.5 1.9 0.084 12.8 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) Laminin_II PF06009.7 CBZ25674.1 - 0.047 13.4 0.4 0.047 13.4 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II Baculo_PEP_C PF04513.7 CBZ25674.1 - 0.12 12.1 2.0 0.21 11.3 0.3 2.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LOH1CR12 PF10158.4 CBZ25674.1 - 0.83 9.4 5.9 5.5 6.7 1.1 3.0 2 1 1 3 3 3 0 Tumour suppressor protein Syntaxin PF00804.20 CBZ25674.1 - 3.1 8.0 17.0 0.82 9.8 1.0 2.8 2 1 0 2 2 2 0 Syntaxin Histone PF00125.19 CBZ25676.1 - 1.6e-16 60.1 1.0 2.2e-16 59.7 0.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ25676.1 - 0.0016 18.4 0.2 0.0033 17.4 0.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DNA_photolyase PF00875.13 CBZ25676.1 - 0.019 14.7 0.1 0.022 14.4 0.1 1.0 1 0 0 1 1 1 0 DNA photolyase Ribosomal_L28 PF00830.14 CBZ25676.1 - 2.3 8.1 4.8 8.5 6.2 3.3 2.0 1 1 0 1 1 1 0 Ribosomal L28 family Histone PF00125.19 CBZ25677.1 - 1.6e-16 60.1 1.0 2.2e-16 59.7 0.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ25677.1 - 0.0016 18.4 0.2 0.0033 17.4 0.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DNA_photolyase PF00875.13 CBZ25677.1 - 0.019 14.7 0.1 0.022 14.4 0.1 1.0 1 0 0 1 1 1 0 DNA photolyase Ribosomal_L28 PF00830.14 CBZ25677.1 - 2.3 8.1 4.8 8.5 6.2 3.3 2.0 1 1 0 1 1 1 0 Ribosomal L28 family Ribosomal_S5_C PF03719.10 CBZ25678.1 - 2.5e-24 84.3 0.0 4.2e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 CBZ25678.1 - 2.7e-21 75.0 0.3 4.6e-21 74.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain FXR1P_C PF12235.3 CBZ25678.1 - 0.12 12.4 2.3 0.21 11.6 1.6 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal SH3_9 PF14604.1 CBZ25679.1 - 6e-09 35.3 0.0 1.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBZ25679.1 - 3.6e-08 32.6 0.0 6.8e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBZ25679.1 - 0.00012 21.4 0.0 0.00027 20.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Sporozoite_P67 PF05642.6 CBZ25679.1 - 2 6.1 4.2 2.7 5.7 2.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DnaJ PF00226.26 CBZ25680.1 - 1.4e-20 72.7 0.5 1.4e-20 72.7 0.3 2.6 2 0 0 2 2 2 1 DnaJ domain DUF865 PF05906.6 CBZ25680.1 - 0.0036 16.8 0.8 0.0064 16.0 0.6 1.4 1 0 0 1 1 1 1 Herpesvirus-7 repeat of unknown function (DUF865) DnaJ PF00226.26 CBZ25681.1 - 0.11 12.2 3.8 3.9 7.2 0.3 3.5 3 1 0 3 3 3 0 DnaJ domain Fibrillarin PF01269.12 CBZ25682.1 - 4.6e-102 339.8 0.0 5.3e-102 339.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CBZ25682.1 - 7.5e-07 28.8 0.0 1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Clathrin_lg_ch PF01086.12 CBZ25683.1 - 5.5e-07 29.7 2.8 6.3e-07 29.5 2.0 1.1 1 0 0 1 1 1 1 Clathrin light chain PAP_central PF04928.12 CBZ25683.1 - 0.099 11.4 0.4 0.11 11.2 0.3 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain Pet127 PF08634.5 CBZ25683.1 - 0.39 9.8 3.0 0.31 10.1 1.2 1.4 1 1 0 2 2 2 0 Mitochondrial protein Pet127 DUF2992 PF11208.3 CBZ25683.1 - 0.99 9.3 7.9 1.4 8.7 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) SNARE PF05739.14 CBZ25684.1 - 1.4e-08 34.2 4.7 8.2e-08 31.8 2.8 2.5 2 0 0 2 2 2 1 SNARE domain PspA_IM30 PF04012.7 CBZ25684.1 - 0.00027 20.3 1.9 0.00049 19.5 0.5 1.9 1 1 1 2 2 2 1 PspA/IM30 family Med9 PF07544.8 CBZ25684.1 - 0.0053 16.4 6.2 0.08 12.6 0.5 2.4 2 0 0 2 2 2 2 RNA polymerase II transcription mediator complex subunit 9 Methyltransf_28 PF02636.12 CBZ25684.1 - 0.016 14.6 0.1 0.021 14.2 0.1 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Vac_Fusion PF02346.11 CBZ25684.1 - 0.061 12.7 2.0 4.6 6.7 0.1 3.1 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Cep57_MT_bd PF06657.8 CBZ25684.1 - 0.063 13.2 8.0 0.43 10.5 1.2 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Sec2p PF06428.6 CBZ25684.1 - 0.12 12.2 0.4 0.12 12.2 0.3 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF87 PF01935.12 CBZ25684.1 - 0.13 12.0 1.0 0.17 11.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 MIF4G_like_2 PF09090.6 CBZ25684.1 - 0.85 8.7 5.2 0.2 10.8 0.7 1.8 1 1 0 2 2 2 0 MIF4G like TPR_MLP1_2 PF07926.7 CBZ25684.1 - 1.1 8.9 9.8 4.5 7.0 1.2 2.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.8 CBZ25684.1 - 3.3 7.2 7.9 3.3 7.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DER1 PF04511.10 CBZ25685.1 - 1.5e-30 106.2 5.8 1.7e-30 106.0 4.0 1.0 1 0 0 1 1 1 1 Der1-like family Pkinase PF00069.20 CBZ25686.1 - 8e-54 182.5 0.0 1.3e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25686.1 - 5.9e-25 87.8 0.0 3e-20 72.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.20 CBZ25686.1 - 9.1e-17 60.5 0.7 1.7e-16 59.6 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.1 CBZ25686.1 - 5.5e-06 25.5 0.0 0.0054 15.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.20 CBZ25687.1 - 5e-57 193.0 0.0 5.7e-57 192.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25687.1 - 8.1e-34 116.8 0.0 9.6e-34 116.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 CBZ25687.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Peptidase_M24 PF00557.19 CBZ25688.1 - 3.8e-29 101.7 1.4 5e-29 101.3 0.9 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pkinase PF00069.20 CBZ25690.1 - 1.9e-71 240.2 0.0 2.3e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25690.1 - 1.4e-32 112.7 0.1 2.9e-31 108.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ25690.1 - 0.052 13.2 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HTH_3 PF01381.17 CBZ25691.1 - 4.5e-11 42.4 0.2 8.6e-11 41.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 CBZ25691.1 - 7.7e-07 29.0 3.3 7.7e-07 29.0 2.3 2.0 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_31 PF13560.1 CBZ25691.1 - 0.0012 18.9 0.6 0.0023 18.0 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 CBZ25691.1 - 0.0017 18.3 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2152 PF10222.4 CBZ25691.1 - 0.026 12.7 0.4 0.031 12.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Mito_carr PF00153.22 CBZ25692.1 - 1.3e-67 223.4 3.5 2e-23 81.9 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 CBZ25693.1 - 1.3e-67 223.4 3.5 2e-23 81.9 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein polyprenyl_synt PF00348.12 CBZ25694.1 - 3.6e-37 127.6 0.0 5.1e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase CrtC PF07143.6 CBZ25694.1 - 4e-26 92.0 0.0 1e-23 84.1 0.0 2.1 2 0 0 2 2 2 2 Hydroxyneurosporene synthase (CrtC) DUF2804 PF10974.3 CBZ25694.1 - 0.084 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) Complex1_LYR PF05347.10 CBZ25695.1 - 1.7e-07 30.9 0.5 2.2e-06 27.3 0.0 2.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBZ25695.1 - 2.2e-05 24.5 0.2 0.00028 21.0 0.0 2.8 2 1 0 2 2 2 1 Complex1_LYR-like GN3L_Grn1 PF08701.6 CBZ25696.1 - 0.00062 19.6 14.7 0.0014 18.4 10.2 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase UVR PF02151.14 CBZ25697.1 - 9e-08 31.3 13.2 0.00017 20.9 0.8 2.8 2 0 0 2 2 2 2 UvrB/uvrC motif zf-Di19 PF05605.7 CBZ25697.1 - 1.7 8.8 24.1 0.079 13.0 4.2 3.1 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Kinesin PF00225.18 CBZ25698.1 - 9.9e-101 336.7 0.6 1.5e-100 336.1 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain VHS PF00790.14 CBZ25698.1 - 2.8e-05 23.7 0.2 0.00011 21.8 0.0 2.2 2 0 0 2 2 2 1 VHS domain Dor1 PF04124.7 CBZ25698.1 - 0.00046 18.7 2.2 0.00091 17.7 1.5 1.4 1 0 0 1 1 1 1 Dor1-like family TPR_MLP1_2 PF07926.7 CBZ25698.1 - 0.048 13.3 18.2 0.22 11.2 6.3 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein EAP30 PF04157.11 CBZ25698.1 - 0.15 11.1 7.8 0.66 9.0 5.4 2.0 1 0 0 1 1 1 0 EAP30/Vps36 family HAUS6_N PF14661.1 CBZ25698.1 - 0.63 9.3 8.9 0.42 9.9 3.5 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Spc24 PF08286.6 CBZ25698.1 - 0.82 9.3 7.3 2.8 7.6 5.0 1.9 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 CBZ25698.1 - 0.86 9.5 5.8 3 7.8 1.5 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Tup_N PF08581.5 CBZ25698.1 - 1.1 9.4 14.4 0.67 10.1 3.8 3.1 3 0 0 3 3 3 0 Tup N-terminal Dynamin_N PF00350.18 CBZ25700.1 - 2.1e-18 66.6 0.0 1.5e-16 60.6 0.0 2.5 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CBZ25700.1 - 2.4e-07 30.7 0.0 5.9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBZ25700.1 - 0.042 13.9 0.1 0.82 9.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain U-box PF04564.10 CBZ25702.1 - 0.0018 18.1 0.0 0.0072 16.2 0.0 2.0 2 0 0 2 2 2 1 U-box domain WEMBL PF05701.6 CBZ25702.1 - 0.023 13.1 0.9 0.034 12.5 0.6 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light UCR_hinge PF02320.11 CBZ25702.1 - 0.03 14.2 3.9 0.074 13.0 2.7 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein zf-CCCH PF00642.19 CBZ25703.1 - 4e-05 23.1 7.0 0.0019 17.8 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) U-box PF04564.10 CBZ25703.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain UPF0016 PF01169.14 CBZ25704.1 - 5.3e-44 148.2 20.5 2.6e-23 81.9 2.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Abhydrolase_9_N PF15420.1 CBZ25704.1 - 0.00059 19.6 2.2 0.00086 19.1 0.1 2.0 1 1 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus Ion_trans PF00520.26 CBZ25704.1 - 0.041 13.1 3.4 0.12 11.5 2.4 1.8 1 1 0 1 1 1 0 Ion transport protein MttA_Hcf106 PF02416.11 CBZ25704.1 - 0.86 8.7 3.8 5.1 6.2 0.1 2.4 2 0 0 2 2 2 0 mttA/Hcf106 family ABC_transp_aux PF09822.4 CBZ25705.1 - 2e-07 30.7 0.0 3.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 ABC-type uncharacterized transport system PDZ_assoc PF10600.4 CBZ25705.1 - 0.11 12.8 0.5 0.26 11.5 0.4 1.6 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors WD40 PF00400.27 CBZ25706.1 - 3.1e-20 71.2 10.6 1e-05 25.2 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBZ25706.1 - 0.0058 15.4 0.0 0.018 13.8 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region DUF1143 PF06608.6 CBZ25707.1 - 0.00043 20.2 0.9 0.82 9.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1143) Radical_SAM PF04055.16 CBZ25708.1 - 1.1e-09 38.7 0.2 1.8e-09 37.9 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DUF2870 PF11069.3 CBZ25708.1 - 0.027 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Pkinase PF00069.20 CBZ25709.1 - 2.4e-30 105.5 0.0 2.7e-16 59.4 0.0 4.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25709.1 - 1.9e-06 27.1 0.2 0.027 13.5 0.1 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.17 CBZ25709.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.27 CBZ25711.1 - 2.3e-17 62.1 0.6 0.00039 20.1 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat PDZ_2 PF13180.1 CBZ25711.1 - 3.6e-06 26.7 0.0 9.3e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBZ25711.1 - 0.27 11.4 0.0 1 9.5 0.0 1.9 1 1 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) PQQ_3 PF13570.1 CBZ25711.1 - 6.8 7.1 7.4 22 5.5 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain Ribosomal_S13_N PF08069.7 CBZ25712.1 - 2.1e-24 85.1 1.7 2.1e-24 85.1 1.2 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CBZ25712.1 - 9.4e-22 76.5 0.4 1.4e-21 75.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 Synaptobrevin PF00957.16 CBZ25713.1 - 7.8e-12 44.6 0.0 1.5e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CBZ25713.1 - 0.023 14.2 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Regulated-SNARE-like domain UMP1 PF05348.6 CBZ25714.1 - 1.6e-06 28.1 0.0 2.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 TFIIS_C PF01096.13 CBZ25715.1 - 5e-19 67.6 2.3 5e-19 67.6 1.6 3.0 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CBZ25715.1 - 0.00046 19.8 1.3 0.00085 18.9 0.1 2.0 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.3 CBZ25715.1 - 0.018 14.4 0.2 0.018 14.4 0.2 2.4 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain DUF2387 PF09526.5 CBZ25715.1 - 0.064 13.1 1.6 2 8.3 0.3 2.5 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) DUF2296 PF10058.4 CBZ25715.1 - 0.067 12.9 4.0 4.9 6.9 0.1 3.3 3 0 0 3 3 3 0 Predicted integral membrane metal-binding protein (DUF2296) TF_Zn_Ribbon PF08271.7 CBZ25715.1 - 0.075 12.3 0.8 3.8 6.9 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-PHD-like PF15446.1 CBZ25715.1 - 0.087 12.1 1.4 0.13 11.5 1.0 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain PhnA_Zn_Ribbon PF08274.7 CBZ25715.1 - 0.13 12.0 6.8 1.5 8.6 0.1 3.0 2 1 1 3 3 3 0 PhnA Zinc-Ribbon DUF4379 PF14311.1 CBZ25715.1 - 0.27 11.0 1.7 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4379) Zn_Tnp_IS1595 PF12760.2 CBZ25715.1 - 0.38 10.6 0.1 0.38 10.6 0.1 3.0 2 1 1 3 3 3 0 Transposase zinc-ribbon domain RRN7 PF11781.3 CBZ25715.1 - 0.48 9.9 5.5 5.1 6.6 0.4 3.3 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Tmemb_55A PF09788.4 CBZ25715.1 - 3.1 6.8 7.8 2.3 7.2 1.2 2.1 1 1 0 2 2 2 0 Transmembrane protein 55A DZR PF12773.2 CBZ25715.1 - 6 6.7 6.7 5.5 6.8 0.1 2.7 2 1 0 2 2 2 0 Double zinc ribbon Ank_4 PF13637.1 CBZ25716.1 - 0.031 14.7 0.0 5.3 7.6 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) NAP PF00956.13 CBZ25717.1 - 1.6e-60 204.2 0.2 1.6e-60 204.2 0.2 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Osteoregulin PF07175.6 CBZ25717.1 - 0.0079 16.0 0.1 0.023 14.5 0.0 1.8 1 1 0 1 1 1 1 Osteoregulin PBP1_TM PF14812.1 CBZ25717.1 - 0.048 13.9 5.4 1.9 8.8 0.4 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 CBZ25717.1 - 0.18 10.2 2.7 0.29 9.5 1.9 1.2 1 0 0 1 1 1 0 Daxx Family Nucleoplasmin PF03066.10 CBZ25717.1 - 0.27 10.7 8.9 2.7 7.4 2.4 2.6 2 0 0 2 2 2 0 Nucleoplasmin DUF2360 PF10152.4 CBZ25719.1 - 1.8e-52 177.5 0.0 2.8e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 CBZ25719.1 - 0.03 13.7 1.8 0.037 13.4 1.3 1.1 1 0 0 1 1 1 0 Vta1 like T6SS_Vgr PF13296.1 CBZ25720.1 - 0.053 13.3 0.1 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 Putative type VI secretion system Rhs element Vgr Lipoprotein_20 PF13942.1 CBZ25723.1 - 0.027 14.0 0.9 0.053 13.0 0.0 1.9 2 0 0 2 2 2 0 YfhG lipoprotein Cep57_MT_bd PF06657.8 CBZ25723.1 - 0.23 11.4 2.5 3.6 7.5 0.4 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 MSP1_C PF07462.6 CBZ25724.1 - 9.5 4.4 3.9 34 2.6 2.7 1.9 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus IQ PF00612.22 CBZ25725.1 - 4.8 7.1 35.1 0.13 11.9 3.9 6.5 6 1 1 7 7 7 0 IQ calmodulin-binding motif LRR_4 PF12799.2 CBZ25726.1 - 3.7e-07 29.5 0.0 0.028 14.0 0.0 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ25726.1 - 0.00086 19.0 0.2 0.13 12.0 0.0 2.5 1 1 0 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 CBZ25726.1 - 3.6 8.1 5.4 29 5.4 0.1 4.4 5 0 0 5 5 5 0 Leucine rich repeat Peptidase_M24 PF00557.19 CBZ25727.1 - 1.8e-42 145.2 0.0 2.3e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 CBZ25727.1 - 8.6e-05 22.3 3.9 0.00018 21.2 2.7 1.6 1 0 0 1 1 1 1 MYND finger IR1-M PF12185.3 CBZ25727.1 - 1.2 8.9 3.8 3 7.6 2.6 1.6 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain DUF1042 PF06294.6 CBZ25728.1 - 2.6e-05 23.8 0.0 4.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1042) G-gamma PF00631.17 CBZ25729.1 - 0.042 13.5 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 GGL domain DUF3481 PF11980.3 CBZ25729.1 - 0.068 12.9 11.4 0.59 9.9 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function (DUF3481) Neurensin PF14927.1 CBZ25729.1 - 3.7 6.9 11.4 3 7.2 0.4 3.5 4 1 0 4 4 4 0 Neurensin IncA PF04156.9 CBZ25729.1 - 4.1 6.9 15.1 5.7 6.4 2.6 4.2 5 0 0 5 5 5 0 IncA protein DUF3481 PF11980.3 CBZ25730.1 - 0.022 14.5 10.3 0.61 9.9 0.0 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3481) G-gamma PF00631.17 CBZ25730.1 - 0.041 13.6 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 GGL domain Prominin PF05478.6 CBZ25730.1 - 6.6 4.1 25.6 0.017 12.7 2.3 2.5 1 1 0 2 2 2 0 Prominin TBCC PF07986.7 CBZ25731.1 - 5.2e-27 93.6 9.3 4.7e-10 38.9 0.0 3.4 3 0 0 3 3 3 3 Tubulin binding cofactor C CAP_C PF08603.6 CBZ25731.1 - 0.26 10.6 0.2 0.59 9.4 0.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Phage-A118_gp45 PF10653.4 CBZ25731.1 - 0.55 10.1 0.0 1.2 8.9 0.0 1.5 1 0 0 1 1 1 0 Protein gp45 of Bacteriophage A118 Pkinase PF00069.20 CBZ25731.1 - 1.3 8.1 0.0 27 3.7 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Pkinase PF00069.20 CBZ25732.1 - 3.3e-42 144.4 0.0 2.3e-33 115.4 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25732.1 - 8e-15 54.6 0.0 4.6e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Cep57_CLD_2 PF14197.1 CBZ25733.1 - 0.18 11.7 2.3 0.38 10.7 1.6 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF2749 PF10907.3 CBZ25734.1 - 0.04 13.7 1.8 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) DUF2975 PF11188.3 CBZ25734.1 - 0.4 10.3 2.5 0.5 10.0 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) CYTH PF01928.16 CBZ25735.1 - 4.1e-12 46.1 0.1 0.00018 21.2 0.0 3.7 4 0 0 4 4 4 3 CYTH domain Histone PF00125.19 CBZ25736.1 - 2.5e-23 81.9 0.5 4e-23 81.3 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ25736.1 - 2.7e-06 27.3 0.0 5.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Gene66 PF02053.10 CBZ25736.1 - 0.0034 16.8 0.3 0.0039 16.6 0.2 1.1 1 0 0 1 1 1 1 Gene 66 (IR5) protein CENP-T PF15511.1 CBZ25736.1 - 0.016 14.4 0.4 0.016 14.4 0.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CENP-S PF15630.1 CBZ25736.1 - 0.044 13.9 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S TAF PF02969.12 CBZ25736.1 - 0.094 12.6 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 TATA box binding protein associated factor (TAF) Ribosomal_L28e PF01778.12 CBZ25736.1 - 3.5 8.0 5.8 8.9 6.7 3.2 2.0 1 1 1 2 2 2 0 Ribosomal L28e protein family ANF_receptor PF01094.23 CBZ25737.1 - 2.5e-27 95.6 8.1 2.2e-21 76.0 1.6 3.4 3 1 0 3 3 3 3 Receptor family ligand binding region Peripla_BP_6 PF13458.1 CBZ25737.1 - 2.4e-05 23.8 5.2 0.00022 20.7 0.5 2.9 2 1 0 2 2 2 2 Periplasmic binding protein Surp PF01805.15 CBZ25738.1 - 0.0023 17.5 0.1 0.0053 16.3 0.0 1.6 1 0 0 1 1 1 1 Surp module RNA_pol_A_bac PF01000.21 CBZ25739.1 - 8.5e-21 74.2 0.0 1.3e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CBZ25739.1 - 2e-10 39.6 0.0 2.7e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_7 PF12838.2 CBZ25739.1 - 0.005 17.1 0.5 0.013 15.8 0.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CBZ25739.1 - 0.057 13.2 0.4 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_9 PF13187.1 CBZ25739.1 - 0.08 13.2 0.6 0.2 11.9 0.4 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4 PF00037.22 CBZ25739.1 - 0.13 11.9 1.2 0.85 9.3 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Utp11 PF03998.8 CBZ25740.1 - 9.8e-54 182.7 26.3 9.8e-54 182.7 18.2 2.0 1 1 1 2 2 2 1 Utp11 protein Kinesin PF00225.18 CBZ25741.1 - 1.1e-90 303.7 2.6 1.1e-90 303.7 0.0 2.4 4 0 0 4 4 4 1 Kinesin motor domain AAA_22 PF13401.1 CBZ25741.1 - 0.13 12.3 1.3 1.2 9.2 0.1 2.9 2 0 0 2 2 2 0 AAA domain Kinesin PF00225.18 CBZ25742.1 - 2e-93 312.7 0.1 1.6e-92 309.7 0.0 2.5 4 0 0 4 4 4 1 Kinesin motor domain Kinesin PF00225.18 CBZ25743.1 - 7.6e-95 317.4 0.8 2e-76 256.8 0.1 4.5 3 0 0 3 3 3 3 Kinesin motor domain Ldh_1_N PF00056.18 CBZ25744.1 - 7.4e-35 119.8 0.5 1.1e-34 119.2 0.4 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBZ25744.1 - 1.4e-31 109.5 0.0 1.9e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CBZ25744.1 - 0.011 14.5 0.0 0.089 11.4 0.0 2.0 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 CBZ25744.1 - 0.029 14.2 0.7 0.052 13.4 0.5 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Reo_sigmaC PF04582.7 CBZ25745.1 - 9.6e-05 21.7 1.2 0.0091 15.2 0.6 2.1 1 1 1 2 2 2 1 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 CBZ25745.1 - 0.00035 20.4 4.7 2.3 8.0 0.4 3.5 1 1 3 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 CBZ25745.1 - 0.00071 19.3 10.2 0.0016 18.1 1.1 3.3 2 2 1 3 3 3 1 Protein of unknown function (DUF1664) Spc7 PF08317.6 CBZ25745.1 - 0.0013 17.4 6.9 0.02 13.5 1.5 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein Prefoldin_2 PF01920.15 CBZ25745.1 - 0.0038 16.9 4.6 0.49 10.1 0.0 3.5 3 1 0 3 3 3 1 Prefoldin subunit Syntaxin_2 PF14523.1 CBZ25745.1 - 0.0064 16.5 0.6 1.7 8.7 0.0 3.1 1 1 2 3 3 3 1 Syntaxin-like protein RmuC PF02646.11 CBZ25745.1 - 0.011 14.5 8.1 0.51 9.1 0.1 3.2 1 1 1 3 3 3 0 RmuC family TPR_MLP1_2 PF07926.7 CBZ25745.1 - 0.013 15.2 7.4 0.29 10.8 0.0 3.7 1 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 CBZ25745.1 - 0.018 14.8 5.6 0.14 11.9 0.0 3.3 1 1 2 4 4 4 0 Laminin Domain II DUF948 PF06103.6 CBZ25745.1 - 0.027 14.3 1.4 6.7 6.6 0.0 3.8 3 2 2 5 5 4 0 Bacterial protein of unknown function (DUF948) Bacillus_HBL PF05791.6 CBZ25745.1 - 0.037 13.3 2.9 0.19 11.1 0.3 2.7 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) LXG PF04740.7 CBZ25745.1 - 0.051 13.3 6.1 0.27 10.9 0.3 2.8 1 1 2 3 3 3 0 LXG domain of WXG superfamily DDE_Tnp_ISL3 PF01610.12 CBZ25745.1 - 0.076 12.5 3.1 0.13 11.7 2.1 1.3 1 0 0 1 1 1 0 Transposase Tropomyosin_1 PF12718.2 CBZ25745.1 - 0.094 12.5 10.4 6.1 6.6 6.8 2.7 1 1 1 2 2 2 0 Tropomyosin like TMP_2 PF06791.8 CBZ25745.1 - 0.11 12.1 1.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 Prophage tail length tape measure protein DUF4208 PF13907.1 CBZ25745.1 - 0.15 12.3 3.1 1.3 9.2 0.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) DUF892 PF05974.7 CBZ25745.1 - 0.24 11.2 9.3 3.9 7.2 3.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Pex19 PF04614.7 CBZ25745.1 - 0.28 10.7 8.5 0.48 10.0 3.6 2.1 1 1 1 2 2 2 0 Pex19 protein family COG2 PF06148.6 CBZ25745.1 - 0.28 11.0 10.2 2.4 8.0 1.5 3.8 1 1 2 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2730 PF10805.3 CBZ25745.1 - 0.3 10.8 0.1 0.3 10.8 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2730) BLOC1_2 PF10046.4 CBZ25745.1 - 0.3 11.2 6.1 32 4.7 0.1 3.8 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MAT1 PF06391.8 CBZ25745.1 - 0.34 10.4 8.5 0.043 13.3 3.0 1.6 2 0 0 2 2 1 0 CDK-activating kinase assembly factor MAT1 AAA_13 PF13166.1 CBZ25745.1 - 0.48 8.8 3.2 0.51 8.7 1.2 1.5 1 1 0 1 1 1 0 AAA domain DUF552 PF04472.7 CBZ25745.1 - 0.69 9.8 4.4 0.81 9.6 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF552) ALIX_LYPXL_bnd PF13949.1 CBZ25745.1 - 0.83 8.5 15.1 0.078 11.9 3.8 2.8 1 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV APG6 PF04111.7 CBZ25745.1 - 0.89 8.5 8.2 0.21 10.6 3.0 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 DASH_Dad3 PF08656.5 CBZ25745.1 - 0.95 9.2 4.6 17 5.1 0.1 3.5 3 1 0 3 3 3 0 DASH complex subunit Dad3 ApoLp-III PF07464.6 CBZ25745.1 - 1.3 9.0 8.1 0.28 11.1 1.1 2.8 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Fmp27_WPPW PF10359.4 CBZ25745.1 - 1.5 7.1 9.2 4.9 5.4 4.1 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4618 PF15397.1 CBZ25745.1 - 1.7 7.9 10.8 0.65 9.2 3.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) V_ATPase_I PF01496.14 CBZ25745.1 - 2.1 6.0 7.0 2.1 6.1 3.0 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CBZ25745.1 - 5.1 6.6 15.8 13 5.3 1.7 3.1 1 1 2 3 3 3 0 IncA protein CENP-H PF05837.7 CBZ25745.1 - 9.4 6.4 11.5 0.65 10.2 2.7 2.6 2 2 0 2 2 2 0 Centromere protein H (CENP-H) DUF2721 PF11026.3 CBZ25745.1 - 9.5 5.8 8.9 1.8 8.1 0.0 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2721) Methyltransf_11 PF08241.7 CBZ25746.1 - 2.1e-10 40.9 0.0 1.2e-09 38.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ25746.1 - 7.9e-10 39.1 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ25746.1 - 1.7e-08 34.3 0.0 4.9e-08 32.8 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ25746.1 - 5.5e-06 26.0 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ25746.1 - 0.00055 20.2 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CBZ25746.1 - 0.0028 17.3 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 CBZ25746.1 - 0.0044 16.1 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 CBZ25746.1 - 0.028 15.0 0.0 0.068 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain EAP30 PF04157.11 CBZ25747.1 - 5.4e-40 136.9 0.1 7.2e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CBZ25747.1 - 4.4e-24 84.1 0.0 7.3e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 WWbp PF10349.4 CBZ25747.1 - 0.0023 18.8 0.5 0.0043 17.9 0.3 1.4 1 0 0 1 1 1 1 WW-domain ligand protein IRS PF02174.12 CBZ25747.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) Mem_trans PF03547.13 CBZ25749.1 - 4.7e-28 97.5 4.1 6.9e-27 93.7 2.9 2.2 1 1 0 1 1 1 1 Membrane transport protein V-SNARE_C PF12352.3 CBZ25750.1 - 3.8e-08 33.2 2.0 3.8e-08 33.2 1.4 2.7 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBZ25750.1 - 2.7e-06 26.9 0.0 9.7e-06 25.2 0.0 1.9 2 0 0 2 2 2 1 Sec20 IncA PF04156.9 CBZ25750.1 - 0.0011 18.6 0.1 0.0011 18.6 0.1 1.7 2 0 0 2 2 2 1 IncA protein MCPsignal PF00015.16 CBZ25750.1 - 0.068 12.7 1.1 0.19 11.2 0.2 2.0 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Poty_PP PF08440.5 CBZ25750.1 - 0.099 11.6 2.0 0.28 10.2 0.4 2.0 1 1 0 2 2 2 0 Potyviridae polyprotein Rabaptin PF03528.10 CBZ25750.1 - 0.23 11.3 3.2 0.11 12.4 0.7 1.6 2 0 0 2 2 2 0 Rabaptin SLT_2 PF13406.1 CBZ25750.1 - 0.23 10.3 2.6 5.9 5.7 0.0 2.4 2 1 0 2 2 2 0 Transglycosylase SLT domain SRP72 PF08492.7 CBZ25752.1 - 1.6e-07 31.6 1.0 1.6e-07 31.6 0.7 2.3 2 0 0 2 2 1 1 SRP72 RNA-binding domain Apc3 PF12895.2 CBZ25752.1 - 2.9e-07 30.5 17.9 1.6e-06 28.1 4.5 5.2 4 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBZ25752.1 - 1.1e-06 28.8 33.7 0.00012 22.3 0.2 7.8 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ25752.1 - 0.0002 21.3 3.3 1.9 8.9 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ25752.1 - 0.0011 19.5 37.4 0.03 14.9 5.4 7.7 7 1 2 9 9 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ25752.1 - 0.017 14.7 17.4 0.6 9.8 0.1 5.0 5 1 0 6 6 6 0 TPR repeat TPR_8 PF13181.1 CBZ25752.1 - 0.081 12.7 6.1 12 5.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ25752.1 - 0.089 13.4 51.4 0.5 11.1 2.2 9.6 7 3 3 10 10 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ25752.1 - 0.18 11.7 0.0 0.18 11.7 0.0 5.9 6 1 2 8 8 8 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ25752.1 - 0.22 11.4 23.9 3 7.9 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ25752.1 - 0.24 11.2 0.1 0.24 11.2 0.0 6.0 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ25752.1 - 0.31 11.6 23.3 18 6.0 1.2 7.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ25752.1 - 1.2 9.7 33.9 4 8.1 0.0 8.8 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ25752.1 - 2.4 7.9 12.0 19 5.0 1.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.22 CBZ25753.1 - 4.1e-43 146.9 0.0 1.1e-20 74.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CBZ25753.1 - 2.8e-23 83.3 0.1 1.9e-08 34.6 0.0 4.2 3 1 0 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 CBZ25753.1 - 5.6e-22 77.3 6.6 5.1e-21 74.3 2.2 2.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 CBZ25753.1 - 3.4e-11 42.8 3.2 0.0019 17.4 0.0 4.9 4 1 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CBZ25753.1 - 4e-09 37.3 0.1 0.0018 19.0 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.1 CBZ25753.1 - 5.5e-07 29.6 0.0 0.015 15.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CBZ25753.1 - 1.1e-06 28.8 0.0 0.0069 16.5 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CBZ25753.1 - 2e-06 28.1 0.1 0.018 15.3 0.0 3.2 4 0 0 4 4 2 2 AAA domain RNA_helicase PF00910.17 CBZ25753.1 - 2.3e-06 27.7 0.2 0.016 15.3 0.0 3.5 4 0 0 4 4 3 1 RNA helicase AAA_29 PF13555.1 CBZ25753.1 - 3.4e-06 26.4 0.1 0.096 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 CBZ25753.1 - 3.6e-06 26.9 0.0 0.1 12.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 CBZ25753.1 - 4.4e-06 27.1 7.8 0.1 12.9 0.0 3.6 4 0 0 4 4 3 2 AAA domain NACHT PF05729.7 CBZ25753.1 - 7.6e-06 25.6 0.0 0.031 13.9 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.1 CBZ25753.1 - 1.2e-05 25.3 2.7 0.027 14.4 0.0 3.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 CBZ25753.1 - 2.3e-05 24.2 0.0 0.81 9.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_13 PF13166.1 CBZ25753.1 - 2.5e-05 22.9 0.2 0.67 8.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 CBZ25753.1 - 3.7e-05 23.4 0.0 0.04 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ25753.1 - 4.7e-05 23.5 0.0 0.086 12.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CBZ25753.1 - 6.5e-05 22.1 0.0 0.31 10.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 CBZ25753.1 - 8.1e-05 22.1 0.0 0.36 10.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 CBZ25753.1 - 0.00017 22.0 0.0 0.26 11.7 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 CBZ25753.1 - 0.00019 21.1 0.1 0.09 12.4 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CBZ25753.1 - 0.00023 20.6 0.1 0.5 9.7 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain UPF0079 PF02367.12 CBZ25753.1 - 0.0004 19.9 0.2 0.01 15.4 0.0 3.0 2 1 1 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 CBZ25753.1 - 0.00068 19.1 0.0 0.26 10.7 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 CBZ25753.1 - 0.0008 19.1 0.0 0.27 10.9 0.0 2.8 3 0 0 3 3 3 1 Archaeal ATPase MMR_HSR1 PF01926.18 CBZ25753.1 - 0.0019 18.1 0.0 1.9 8.4 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.1 CBZ25753.1 - 0.0019 18.0 0.1 0.44 10.4 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 CBZ25753.1 - 0.003 17.2 0.0 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 CBZ25753.1 - 0.0037 16.3 0.0 0.084 11.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 CBZ25753.1 - 0.011 14.8 0.0 4.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 CBZ25753.1 - 0.018 13.8 0.6 0.66 8.6 0.0 2.6 3 0 0 3 3 3 0 ArgK protein Rad17 PF03215.10 CBZ25753.1 - 0.02 13.6 0.1 0.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ATP-synt_ab PF00006.20 CBZ25753.1 - 0.022 14.2 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 CBZ25753.1 - 0.029 14.0 0.0 0.77 9.4 0.0 2.4 2 0 0 2 2 2 0 NTPase SRP54 PF00448.17 CBZ25753.1 - 0.031 13.7 0.1 0.66 9.3 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.14 CBZ25753.1 - 0.032 13.6 0.1 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 CBZ25753.1 - 0.036 13.4 0.0 2.5 7.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.17 CBZ25753.1 - 0.038 12.8 0.0 6.1 5.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 CBZ25753.1 - 0.04 13.4 1.4 1.2 8.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain VirE PF05272.6 CBZ25753.1 - 0.04 13.3 0.0 14 5.0 0.0 3.1 3 0 0 3 3 3 0 Virulence-associated protein E Sigma54_activ_2 PF14532.1 CBZ25753.1 - 0.04 13.9 0.0 1.1 9.2 0.0 2.8 3 0 0 3 3 2 0 Sigma-54 interaction domain RuvB_N PF05496.7 CBZ25753.1 - 0.049 12.6 0.1 0.34 9.9 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 CBZ25753.1 - 0.07 11.8 0.0 2.4 6.7 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain Vps53_N PF04100.7 CBZ25754.1 - 6.8e-65 219.3 10.6 9.4e-65 218.8 7.3 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal COG2 PF06148.6 CBZ25754.1 - 0.0034 17.2 1.0 0.0099 15.7 0.7 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 CBZ25754.1 - 0.049 12.8 1.7 0.098 11.8 1.2 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein XhlA PF10779.4 CBZ25754.1 - 0.31 10.9 3.5 0.78 9.7 0.2 2.6 2 0 0 2 2 2 0 Haemolysin XhlA Atg8 PF02991.11 CBZ25755.1 - 6.6e-11 42.1 0.0 8.5e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.11 CBZ25755.1 - 0.021 14.8 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR APG5 PF04106.7 CBZ25755.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 Atg8 PF02991.11 CBZ25756.1 - 6.6e-11 42.1 0.0 8.5e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.11 CBZ25756.1 - 0.021 14.8 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR APG5 PF04106.7 CBZ25756.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 Atg8 PF02991.11 CBZ25757.1 - 6.6e-11 42.1 0.0 8.5e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.11 CBZ25757.1 - 0.021 14.8 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR APG5 PF04106.7 CBZ25757.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 Atg8 PF02991.11 CBZ25758.1 - 7.4e-11 41.9 0.0 9.5e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.11 CBZ25758.1 - 0.023 14.6 0.0 0.026 14.5 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR APG5 PF04106.7 CBZ25758.1 - 0.17 11.3 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 Atg8 PF02991.11 CBZ25759.1 - 6.6e-11 42.1 0.0 8.5e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.11 CBZ25759.1 - 0.021 14.8 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR APG5 PF04106.7 CBZ25759.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 Atg8 PF02991.11 CBZ25761.1 - 1.1e-11 44.6 0.0 1.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.11 CBZ25761.1 - 0.08 12.9 0.0 0.092 12.7 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Atg8 PF02991.11 CBZ25762.1 - 6.4e-11 42.1 0.0 8.3e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.11 CBZ25762.1 - 0.017 15.1 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR APG5 PF04106.7 CBZ25762.1 - 0.15 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 BT1 PF03092.11 CBZ25763.1 - 1.4e-166 554.5 13.4 1.6e-166 554.3 9.3 1.0 1 0 0 1 1 1 1 BT1 family DUF4044 PF13253.1 CBZ25763.1 - 1.7 7.8 6.2 7 5.8 4.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) CAP_GLY PF01302.20 CBZ25765.1 - 4.9e-19 67.8 0.2 7.3e-19 67.2 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF1878 PF08963.5 CBZ25765.1 - 2.7 8.2 10.5 0.55 10.4 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1878) Dynein_light PF01221.13 CBZ25767.1 - 2.3e-29 101.2 0.3 2.8e-29 100.9 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 FKBP_C PF00254.23 CBZ25768.1 - 2.8e-12 46.4 0.0 4.2e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cytochrom_B561 PF03188.11 CBZ25768.1 - 0.15 11.8 0.1 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 FYVE PF01363.16 CBZ25769.1 - 5.2e-13 48.6 10.8 2.9e-12 46.2 7.5 2.1 1 1 0 1 1 1 1 FYVE zinc finger AMP-binding PF00501.23 CBZ25770.1 - 4.2e-85 285.6 3.0 5.2e-85 285.3 2.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ25770.1 - 9.8e-10 39.2 0.3 3.4e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 CBZ25771.1 - 1e-84 284.3 2.9 1.3e-84 284.0 2.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ25771.1 - 9.7e-10 39.2 0.3 3.3e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HSP33 PF01430.14 CBZ25771.1 - 0.061 12.4 0.0 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Hsp33 protein AMP-binding PF00501.23 CBZ25772.1 - 7.9e-77 258.3 0.1 1e-76 258.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ25772.1 - 8.1e-10 39.5 0.0 3.5e-09 37.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 CBZ25773.1 - 6e-22 76.6 0.1 6.3e-07 29.0 0.1 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat eIF2A PF08662.6 CBZ25773.1 - 0.0056 16.4 0.0 0.1 12.3 0.0 2.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PseudoU_synth_1 PF01416.15 CBZ25774.1 - 1.6e-11 44.5 0.6 9.1e-09 35.6 0.0 3.5 4 0 0 4 4 4 1 tRNA pseudouridine synthase Filaggrin PF03516.8 CBZ25774.1 - 5.8 7.4 11.0 1.6 9.2 0.9 3.3 2 1 1 3 3 3 0 Filaggrin Cir_N PF10197.4 CBZ25775.1 - 8.1 6.5 15.7 0.083 12.9 3.8 3.1 3 1 1 4 4 4 0 N-terminal domain of CBF1 interacting co-repressor CIR B3_4 PF03483.12 CBZ25776.1 - 1.7e-18 66.6 0.0 3.4e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CBZ25776.1 - 1.7e-18 66.1 0.0 2e-15 56.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain Prominin PF05478.6 CBZ25778.1 - 0.51 7.8 1.5 0.95 6.9 1.0 1.3 1 0 0 1 1 1 0 Prominin DAGK_cat PF00781.19 CBZ25779.1 - 1.2e-10 40.8 0.2 1.1e-07 31.3 0.2 3.2 2 1 0 2 2 2 2 Diacylglycerol kinase catalytic domain Hum_adeno_E3A PF05393.6 CBZ25781.1 - 0.16 11.6 1.9 3.4 7.3 0.1 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein DUF1515 PF07439.6 CBZ25782.1 - 0.33 10.7 3.3 1.5 8.7 2.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) Mto2_bdg PF12808.2 CBZ25782.1 - 0.84 9.7 8.2 0.11 12.5 1.0 3.1 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Mito_carr PF00153.22 CBZ25783.1 - 1.9e-55 184.5 5.8 1.1e-18 66.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PCI PF01399.22 CBZ25784.1 - 1.6e-08 34.8 0.0 6.1e-08 32.9 0.0 2.1 2 0 0 2 2 2 1 PCI domain DUF1843 PF08898.5 CBZ25784.1 - 0.01 15.8 0.0 0.51 10.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Ank_2 PF12796.2 CBZ25785.1 - 4.3e-30 103.8 20.0 6.5e-06 26.3 0.1 12.0 11 2 2 13 13 13 6 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ25785.1 - 7.5e-21 72.8 36.4 0.00068 19.3 0.1 14.9 16 0 0 16 16 16 6 Ankyrin repeat Ank_3 PF13606.1 CBZ25785.1 - 3.4e-16 57.7 29.2 0.064 13.5 0.1 15.8 16 0 0 16 16 16 3 Ankyrin repeat Ank_4 PF13637.1 CBZ25785.1 - 6.4e-12 45.6 16.9 0.029 14.8 0.0 10.8 11 1 3 14 14 14 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ25785.1 - 1.4e-11 44.2 28.9 0.018 15.3 0.2 12.7 13 1 1 14 14 14 4 Ankyrin repeats (many copies) DUF1501 PF07394.7 CBZ25786.1 - 0.079 11.7 1.7 0.15 10.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF1675 PF07897.6 CBZ25788.1 - 0.055 13.3 7.8 0.12 12.1 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Ycf1 PF05758.7 CBZ25788.1 - 0.8 7.3 3.7 0.77 7.3 2.6 1.1 1 0 0 1 1 1 0 Ycf1 Pox_Ag35 PF03286.9 CBZ25788.1 - 2.8 7.4 11.6 0.33 10.4 5.1 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Lzipper-MIP1 PF14389.1 CBZ25789.1 - 0.16 12.0 5.7 6.9 6.8 0.0 3.4 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CHCH PF06747.8 CBZ25791.1 - 8.6e-07 28.7 1.5 1.4e-06 28.0 1.0 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CBZ25791.1 - 0.0057 16.3 1.3 0.013 15.3 0.9 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 CBZ25791.1 - 0.033 14.2 2.3 0.24 11.4 0.6 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF1903 PF08991.5 CBZ25791.1 - 0.064 13.4 0.2 0.087 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Pet191_N PF10203.4 CBZ25791.1 - 0.27 11.2 1.7 0.67 10.0 1.2 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Actin PF00022.14 CBZ25792.1 - 1.9e-85 286.6 0.0 2.4e-85 286.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CBZ25792.1 - 0.0099 14.4 0.0 2.6 6.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Fcf1 PF04900.7 CBZ25793.1 - 1.7e-35 121.1 1.8 1.7e-35 121.1 1.3 1.7 2 0 0 2 2 2 1 Fcf1 NPFF PF15085.1 CBZ25793.1 - 0.078 13.2 0.2 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Neuropeptide FF Apc3 PF12895.2 CBZ25794.1 - 0.0081 16.2 2.7 0.02 14.9 1.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 CBZ25794.1 - 0.037 14.4 1.1 0.072 13.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.15 CBZ25794.1 - 0.038 13.6 0.1 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin NMD3 PF04981.8 CBZ25794.1 - 0.093 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 NMD3 family TPR_12 PF13424.1 CBZ25794.1 - 0.31 11.0 3.7 0.093 12.6 0.5 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat LEA_3 PF03242.8 CBZ25795.1 - 0.46 10.7 6.0 0.77 10.0 0.5 3.0 2 1 1 3 3 3 0 Late embryogenesis abundant protein Pex2_Pex12 PF04757.9 CBZ25797.1 - 5.3e-39 133.9 0.1 8.1e-39 133.3 0.0 1.3 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CBZ25797.1 - 0.00052 19.9 4.3 0.00087 19.2 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ25797.1 - 0.0051 16.6 3.5 0.0089 15.8 2.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBZ25797.1 - 0.05 13.2 5.2 0.13 11.9 3.6 1.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Surp PF01805.15 CBZ25799.1 - 1e-08 34.6 2.3 1e-08 34.6 1.6 2.0 2 1 0 2 2 2 1 Surp module Band_7 PF01145.20 CBZ25800.1 - 7.6e-28 97.6 0.2 6.3e-27 94.6 0.0 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 CBZ25800.1 - 0.0086 15.6 0.3 0.021 14.3 0.0 1.8 2 0 0 2 2 2 1 SPFH domain-Band 7 family V_ATPase_I PF01496.14 CBZ25800.1 - 0.042 11.7 0.6 0.044 11.6 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Band_7 PF01145.20 CBZ25801.1 - 1.9e-23 83.3 0.0 2.6e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Pkinase PF00069.20 CBZ25802.1 - 2.8e-05 23.4 0.0 0.00018 20.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25802.1 - 0.0012 17.9 0.0 0.051 12.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SH3_4 PF06347.8 CBZ25803.1 - 0.03 13.8 0.0 0.086 12.3 0.0 1.8 1 0 0 1 1 1 0 Bacterial SH3 domain Calsequestrin PF01216.12 CBZ25803.1 - 0.039 12.7 0.2 0.055 12.2 0.2 1.1 1 0 0 1 1 1 0 Calsequestrin MBOAT PF03062.14 CBZ25805.1 - 1.3e-31 109.9 15.2 2.1e-31 109.2 10.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 CBZ25806.1 - 8e-31 107.3 18.6 1.6e-30 106.3 12.9 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT PF03062.14 CBZ25807.1 - 1.1e-30 106.8 29.7 1.5e-29 103.1 14.3 3.7 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PAP2 PF01569.16 CBZ25808.1 - 6.7e-20 71.0 2.7 6.7e-20 71.0 1.9 2.3 2 1 0 2 2 2 1 PAP2 superfamily Mtp PF03821.11 CBZ25808.1 - 0.013 14.9 4.2 0.013 14.9 1.0 1.9 2 0 0 2 2 2 0 Golgi 4-transmembrane spanning transporter PAP2_3 PF14378.1 CBZ25808.1 - 0.014 14.9 0.3 0.014 14.9 0.2 2.2 2 0 0 2 2 2 0 PAP2 superfamily DUF4051 PF13260.1 CBZ25808.1 - 0.058 12.7 0.2 0.18 11.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) RDD PF06271.7 CBZ25808.1 - 1.4 8.8 7.7 0.5 10.2 2.1 2.1 2 0 0 2 2 2 0 RDD family DUF4131 PF13567.1 CBZ25808.1 - 2 7.7 9.1 3.1 7.1 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PAP2 PF01569.16 CBZ25809.1 - 3e-20 72.1 2.7 4.3e-20 71.6 1.9 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 CBZ25809.1 - 0.0055 16.2 0.3 0.0099 15.4 0.2 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF898 PF05987.8 CBZ25810.1 - 0.0076 15.1 0.2 0.01 14.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) BatA PF07584.6 CBZ25810.1 - 0.11 12.7 1.5 0.39 10.9 0.7 2.1 2 1 1 3 3 3 0 Aerotolerance regulator N-terminal DUF202 PF02656.10 CBZ25810.1 - 0.12 12.6 1.4 0.88 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF2970 PF11174.3 CBZ25810.1 - 0.2 11.2 2.8 2.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) PDZ_2 PF13180.1 CBZ25812.1 - 0.019 14.8 0.0 0.084 12.7 0.0 2.0 2 0 0 2 2 2 0 PDZ domain Matrilin_ccoil PF10393.4 CBZ25812.1 - 0.035 13.4 3.8 0.073 12.4 0.3 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin PDZ PF00595.19 CBZ25812.1 - 0.064 13.4 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) YlbD_coat PF14071.1 CBZ25812.1 - 0.31 11.1 1.6 0.56 10.2 0.2 2.0 2 0 0 2 2 2 0 Putative coat protein BBP1_C PF15272.1 CBZ25812.1 - 0.53 9.7 3.9 0.92 9.0 0.4 2.2 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Cation_efflux PF01545.16 CBZ25813.1 - 1.2e-32 113.1 8.8 5.3e-31 107.7 4.8 2.6 1 1 1 2 2 2 1 Cation efflux family TBP PF00352.16 CBZ25814.1 - 1.2e-32 111.0 0.1 4.7e-18 64.3 0.0 2.6 2 1 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) TPR_17 PF13431.1 CBZ25815.1 - 7.3e-08 32.0 0.6 0.035 14.3 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ25815.1 - 1.9e-07 30.3 1.2 0.001 18.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ25815.1 - 2.4e-07 30.1 6.6 0.0027 17.5 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ25815.1 - 1.7e-06 27.5 2.6 0.44 10.2 0.1 4.4 2 2 1 4 4 4 2 TPR repeat TPR_12 PF13424.1 CBZ25815.1 - 2.7e-05 24.0 1.5 0.0013 18.6 0.2 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ25815.1 - 0.00011 22.3 1.6 0.16 12.5 0.0 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ25815.1 - 0.00029 21.1 0.0 2 9.2 0.0 4.2 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ25815.1 - 0.001 18.6 1.4 0.04 13.6 0.0 4.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Sel1 PF08238.7 CBZ25815.1 - 0.0021 18.6 3.0 0.61 10.7 0.1 3.4 3 1 0 3 3 3 1 Sel1 repeat TPR_16 PF13432.1 CBZ25815.1 - 0.0029 18.2 0.5 9 7.1 0.1 3.8 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 CBZ25815.1 - 0.037 13.9 0.1 0.037 13.9 0.1 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ25815.1 - 0.057 13.2 0.2 0.39 10.6 0.1 2.6 2 1 0 2 2 1 0 Tetratricopeptide repeat Lambda_Kil PF06301.6 CBZ25815.1 - 0.085 12.2 0.1 0.2 11.1 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein PAP_assoc PF03828.14 CBZ25816.1 - 2.4e-14 52.9 0.2 5.4e-14 51.8 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Peptidase_C1 PF00112.18 CBZ25817.1 - 1.4e-68 231.0 1.4 2e-68 230.5 1.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBZ25817.1 - 7.3e-08 32.5 0.3 1.3e-07 31.8 0.2 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBZ25817.1 - 1.1e-05 24.1 1.2 0.0013 17.3 0.0 2.5 2 1 0 3 3 3 2 Peptidase C1-like family PIH1 PF08190.7 CBZ25818.1 - 1.1e-15 57.9 0.0 2.8e-14 53.3 0.0 2.0 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Pkinase PF00069.20 CBZ25819.1 - 1.6e-66 224.1 0.0 1.8e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25819.1 - 1.8e-33 115.7 0.0 2.6e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25819.1 - 7.2e-07 28.4 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ25819.1 - 0.0018 18.0 1.2 0.0024 17.6 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ25819.1 - 0.027 13.5 0.5 0.059 12.4 0.3 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_1 PF00175.16 CBZ25820.1 - 1.9e-11 44.4 0.0 3.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Oxidored-like PF09791.4 CBZ25820.1 - 2.3e-11 42.9 1.3 4.8e-11 41.9 0.9 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal FAD_binding_1 PF00667.15 CBZ25820.1 - 2.7e-07 30.2 0.0 0.0035 16.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain COX6B PF02297.12 CBZ25821.1 - 0.011 15.7 1.8 0.024 14.6 1.2 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.20 CBZ25822.1 - 8e-40 136.6 0.0 1.9e-26 92.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25822.1 - 8e-17 61.1 0.0 1.4e-14 53.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase IF4E PF01652.13 CBZ25823.1 - 3.6e-42 143.7 0.0 4.9e-42 143.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DNA_pol_E_B PF04042.11 CBZ25823.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B TPT PF03151.11 CBZ25825.1 - 2.2e-25 89.0 9.9 2.2e-25 89.0 6.9 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CBZ25825.1 - 9.3e-05 21.4 25.9 0.00036 19.5 17.9 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBZ25825.1 - 0.00061 19.8 9.3 0.00061 19.8 6.4 2.8 1 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CBZ25825.1 - 0.081 13.1 23.6 0.041 14.0 4.9 3.1 2 1 2 4 4 4 0 Multidrug resistance efflux transporter DUF4131 PF13567.1 CBZ25825.1 - 0.32 10.3 9.3 7.4 5.9 0.1 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4131) IF3_N PF05198.11 CBZ25826.1 - 0.021 14.7 0.3 0.071 13.0 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor IF-3, N-terminal domain Peptidase_S13 PF02113.10 CBZ25826.1 - 0.14 10.6 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family FKBP_C PF00254.23 CBZ25827.1 - 1.1e-30 105.5 0.0 1.2e-29 102.1 0.0 2.5 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 CBZ25827.1 - 8.1e-14 51.0 0.9 3.5e-08 32.9 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBZ25827.1 - 1.9e-11 42.9 0.5 0.00019 21.0 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ25827.1 - 1.4e-09 37.1 0.4 0.015 14.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ25827.1 - 2.1e-08 34.5 3.0 0.0046 17.5 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ25827.1 - 6e-08 32.9 1.6 4.6e-06 26.8 1.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ25827.1 - 9.2e-08 31.9 0.3 0.0015 18.3 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ25827.1 - 5.2e-07 29.7 3.8 0.00082 19.8 0.4 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ25827.1 - 6.7e-05 22.7 2.1 0.0038 17.2 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ25827.1 - 0.00011 22.2 0.1 0.00021 21.3 0.1 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CBZ25827.1 - 0.00038 20.2 0.0 0.0034 17.2 0.0 2.3 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 CBZ25827.1 - 0.00042 20.1 0.9 0.98 9.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ25827.1 - 0.00056 19.4 0.1 1.6 8.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ25827.1 - 0.0026 17.4 0.7 0.11 12.3 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ25827.1 - 0.0061 16.9 1.1 0.1 13.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ25827.1 - 0.016 15.6 0.3 28 5.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Carn_acyltransf PF00755.15 CBZ25828.1 - 2.5e-125 418.8 0.0 2e-90 303.5 0.0 2.1 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase WD40 PF00400.27 CBZ25829.1 - 6.2e-14 51.2 3.6 4.3e-06 26.4 0.0 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 CBZ25829.1 - 0.15 10.9 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IMPDH PF00478.20 CBZ25830.1 - 1.9e-131 438.1 3.3 2.2e-131 437.9 2.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CBZ25830.1 - 1.3e-14 53.6 0.1 5.9e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 CBZ25830.1 - 1.4e-09 37.2 0.2 1.4e-09 37.2 0.2 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 CBZ25830.1 - 8.2e-07 28.4 2.1 0.011 14.8 0.5 2.5 3 0 0 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 CBZ25830.1 - 0.026 13.7 0.1 0.4 9.9 0.0 2.2 1 1 0 2 2 2 0 Histidine biosynthesis protein ELMO_CED12 PF04727.8 CBZ25831.1 - 8e-29 100.3 0.0 1.1e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Peptidase_M41 PF01434.13 CBZ25833.1 - 9.3e-45 152.7 0.4 1.5e-44 152.0 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBZ25833.1 - 2e-40 138.0 0.0 2.4e-39 134.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ25833.1 - 2e-05 24.7 0.5 0.0006 19.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ25833.1 - 0.00028 20.9 9.5 0.0091 15.9 0.1 4.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 CBZ25833.1 - 0.00029 20.5 1.4 0.0017 18.0 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 CBZ25833.1 - 0.00034 21.4 0.0 0.0011 19.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ25833.1 - 0.00073 19.2 0.0 0.0031 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBZ25833.1 - 0.0034 16.4 0.0 0.0083 15.1 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CBZ25833.1 - 0.0048 15.6 0.0 0.01 14.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 CBZ25833.1 - 0.0048 16.3 3.4 0.01 15.2 0.1 2.6 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBZ25833.1 - 0.011 15.1 0.1 0.027 13.8 0.1 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 CBZ25833.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_M50B PF13398.1 CBZ25833.1 - 0.029 13.7 0.7 0.044 13.1 0.0 1.6 2 0 0 2 2 1 0 Peptidase M50B-like DUF2075 PF09848.4 CBZ25833.1 - 0.035 13.0 0.0 0.063 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.9 CBZ25833.1 - 0.042 13.7 0.0 0.18 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 CBZ25833.1 - 0.091 12.8 0.2 5.4 7.0 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 CBZ25833.1 - 0.092 12.4 0.1 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 CBZ25833.1 - 0.12 12.6 0.1 0.3 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 CBZ25833.1 - 0.15 11.1 0.1 0.47 9.5 0.1 1.8 1 0 0 1 1 1 0 KaiC NTPase_1 PF03266.10 CBZ25833.1 - 0.15 11.7 0.4 0.63 9.7 0.1 2.1 1 1 1 2 2 2 0 NTPase SRP19 PF01922.12 CBZ25834.1 - 5.1e-28 97.4 0.1 1.2e-27 96.2 0.1 1.6 1 1 0 1 1 1 1 SRP19 protein COMPASS-Shg1 PF05205.7 CBZ25834.1 - 0.043 14.1 0.0 0.072 13.3 0.0 1.3 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 RuvA_C PF07499.8 CBZ25834.1 - 0.13 12.4 0.0 0.86 9.8 0.0 2.2 2 1 1 3 3 3 0 RuvA, C-terminal domain Pkinase PF00069.20 CBZ25835.1 - 5.5e-18 65.0 0.0 7e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25835.1 - 1e-05 24.7 0.0 2.5e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase BTB_2 PF02214.17 CBZ25836.1 - 7.7e-13 48.4 0.0 2.1e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Atg8 PF02991.11 CBZ25837.1 - 1.7e-38 130.7 0.0 2e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CBZ25837.1 - 9.1e-08 32.1 0.0 1.2e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Galactosyl_T PF01762.16 CBZ25840.1 - 0.00027 20.6 0.2 0.00079 19.0 0.0 1.8 2 0 0 2 2 2 1 Galactosyltransferase Histone PF00125.19 CBZ25841.1 - 1.1e-13 51.1 0.7 1.3e-13 50.8 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ25841.1 - 6.6e-05 22.8 0.8 7.1e-05 22.7 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CBZ25841.1 - 0.0003 20.6 0.2 0.00048 20.0 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CBZ25841.1 - 0.00065 19.3 0.0 0.00083 19.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CBZ25841.1 - 0.0016 18.1 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 CBZ25841.1 - 0.086 12.7 1.0 0.17 11.7 0.2 2.0 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit FbpA PF05833.6 CBZ25841.1 - 0.086 11.3 0.0 0.1 11.1 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Amidohydro_4 PF13147.1 CBZ25843.1 - 1.1e-22 81.3 0.0 1.4e-22 81.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 CBZ25843.1 - 3.9e-07 30.0 2.4 9.2e-06 25.5 1.6 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CBZ25843.1 - 4.2e-06 26.2 0.1 0.031 13.5 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 CBZ25843.1 - 0.0013 18.4 0.0 0.0034 17.1 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase PUF PF00806.14 CBZ25844.1 - 4.9e-33 110.7 11.4 6.4e-06 25.3 0.1 7.4 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat NatB_MDM20 PF09797.4 CBZ25844.1 - 0.00061 18.6 0.3 0.0011 17.7 0.2 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit CYTH PF01928.16 CBZ25844.1 - 0.044 13.4 0.0 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 CYTH domain FGGY_C PF02782.11 CBZ25845.1 - 2.4e-36 125.2 0.1 4.2e-36 124.4 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CBZ25845.1 - 3.5e-09 36.3 0.0 7.8e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain SAP PF02037.22 CBZ25846.1 - 1.9e-12 46.3 0.4 3e-12 45.7 0.3 1.4 1 0 0 1 1 1 1 SAP domain EGF_alliinase PF04863.8 CBZ25846.1 - 0.028 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain TPR_11 PF13414.1 CBZ25847.1 - 3.5e-54 180.3 19.0 1.8e-16 59.5 0.1 4.1 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 CBZ25847.1 - 1.9e-38 128.5 15.9 4.7e-07 29.1 0.4 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ25847.1 - 3.5e-33 110.8 11.0 2.4e-07 30.1 0.0 6.3 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ25847.1 - 1e-18 65.6 10.6 4.6e-06 26.0 0.0 6.2 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ25847.1 - 9.4e-18 63.9 6.8 2e-05 24.4 0.1 4.2 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ25847.1 - 7.9e-16 56.5 1.6 0.0003 20.3 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ25847.1 - 2.4e-15 56.6 2.7 0.014 16.0 0.0 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ25847.1 - 5.4e-15 54.5 1.7 0.003 18.0 0.0 5.7 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ25847.1 - 2e-13 49.3 6.4 0.014 15.5 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ25847.1 - 6.2e-11 42.0 9.2 0.0015 18.8 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ25847.1 - 5.7e-10 39.3 6.9 0.0089 16.3 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ25847.1 - 7.4e-10 38.5 0.4 0.0012 18.5 0.1 3.7 3 1 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBZ25847.1 - 2e-08 33.3 3.4 0.013 14.7 0.0 4.6 5 0 0 5 5 5 3 SHNi-TPR MIT PF04212.13 CBZ25847.1 - 3.1e-07 30.1 11.0 0.045 13.6 0.1 4.4 4 0 0 4 4 4 3 MIT (microtubule interacting and transport) domain Apc3 PF12895.2 CBZ25847.1 - 4.5e-07 29.9 7.4 0.00023 21.2 0.1 3.1 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CBZ25847.1 - 0.00012 21.9 1.8 0.54 10.2 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat SPO22 PF08631.5 CBZ25847.1 - 0.00026 20.1 1.1 0.19 10.7 0.1 3.1 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_3 PF07720.7 CBZ25847.1 - 0.0028 17.4 7.1 0.028 14.2 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.2 CBZ25847.1 - 0.0057 16.4 1.7 1.2 8.9 0.1 3.1 2 2 0 2 2 2 1 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 CBZ25847.1 - 0.0087 15.9 1.6 0.43 10.4 0.0 4.1 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat Glyoxalase_2 PF12681.2 CBZ25847.1 - 0.03 14.9 0.1 4.5 7.9 0.0 2.5 2 2 0 2 2 2 0 Glyoxalase-like domain Porph_ging PF09697.5 CBZ25847.1 - 0.046 13.8 0.4 6.8 6.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (Porph_ging) Egg_lysin PF01303.12 CBZ25847.1 - 0.11 12.5 0.3 0.3 11.0 0.1 1.7 2 0 0 2 2 2 0 Egg lysin (Sperm-lysin) DUF3560 PF12083.3 CBZ25847.1 - 0.19 11.7 2.5 4.2 7.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3560) DUF2225 PF09986.4 CBZ25847.1 - 0.59 9.5 5.4 9.8 5.5 0.6 3.1 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Sel1 PF08238.7 CBZ25847.1 - 3 8.6 13.2 7.3 7.3 0.3 4.6 4 1 1 5 5 4 0 Sel1 repeat LCM PF04072.9 CBZ25848.1 - 3.1e-27 95.3 0.0 3.9e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase IMS PF00817.15 CBZ25850.1 - 6e-34 116.9 0.1 1.3e-33 115.8 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CBZ25850.1 - 3e-06 27.1 0.0 1.5e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 impB/mucB/samB family C-terminal domain Pox_MCEL PF03291.11 CBZ25852.1 - 9e-31 106.9 0.0 8.6e-30 103.7 0.0 1.9 1 1 0 1 1 1 1 mRNA capping enzyme NNMT_PNMT_TEMT PF01234.12 CBZ25852.1 - 0.0081 15.1 0.1 0.16 10.9 0.1 2.1 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.1 CBZ25852.1 - 0.0089 15.7 0.0 0.046 13.4 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain PUB PF09409.5 CBZ25853.1 - 9e-17 60.6 0.0 1.9e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 PUB domain HEAT PF02985.17 CBZ25854.1 - 0.13 12.3 2.4 0.24 11.5 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat His_Phos_1 PF00300.17 CBZ25855.1 - 1.1e-28 100.3 0.0 5.1e-28 98.1 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CBZ25855.1 - 0.094 12.0 0.0 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) GTP_EFTU PF00009.22 CBZ25858.1 - 2.4e-61 206.4 0.3 3.7e-61 205.8 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CBZ25858.1 - 1e-35 121.9 0.0 2.6e-35 120.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CBZ25858.1 - 6.4e-21 74.0 0.0 2.8e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 CBZ25858.1 - 7.7e-14 51.3 0.1 3.5e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CBZ25858.1 - 3e-13 49.6 0.1 8.8e-13 48.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Peptidase_S24 PF00717.18 CBZ25859.1 - 2.7e-06 26.8 0.0 4.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CBZ25859.1 - 0.0014 18.1 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 DUF551 PF04448.7 CBZ25859.1 - 0.028 15.1 0.7 0.13 12.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF551) SET PF00856.23 CBZ25860.1 - 5.6e-08 33.2 0.1 9.2e-07 29.3 0.1 2.2 1 1 0 1 1 1 1 SET domain RimK PF08443.6 CBZ25860.1 - 0.00049 19.6 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Propep_M14 PF02244.11 CBZ25860.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Glycos_transf_2 PF00535.21 CBZ25861.1 - 1.2e-30 106.4 0.0 1.5e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CBZ25861.1 - 4.1e-05 23.5 0.0 4.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 FKBP_C PF00254.23 CBZ25862.1 - 9.7e-27 92.8 0.0 1.1e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ADIP PF11559.3 CBZ25863.1 - 2.1e-06 27.7 12.3 2.1e-06 27.7 8.5 1.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF4164 PF13747.1 CBZ25863.1 - 1.5e-05 25.0 7.1 1.5e-05 25.0 4.9 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4164) HAP1_N PF04849.8 CBZ25863.1 - 0.00045 19.2 6.0 0.00045 19.2 4.2 1.5 2 0 0 2 2 2 1 HAP1 N-terminal conserved region Fib_alpha PF08702.5 CBZ25863.1 - 0.028 14.5 8.0 0.5 10.4 3.8 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3840 PF12944.2 CBZ25863.1 - 0.031 14.1 1.6 0.056 13.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3840) Stonin2_N PF12016.3 CBZ25863.1 - 0.035 13.2 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Stonin 2 bZIP_1 PF00170.16 CBZ25863.1 - 0.061 13.2 1.9 0.061 13.2 1.3 3.5 2 2 0 3 3 3 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 CBZ25863.1 - 0.12 12.2 22.6 0.14 11.9 13.4 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4446 PF14584.1 CBZ25863.1 - 0.15 11.8 7.9 0.16 11.7 1.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) APG6 PF04111.7 CBZ25863.1 - 0.19 10.7 11.7 0.12 11.3 5.8 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 AAA_13 PF13166.1 CBZ25863.1 - 0.24 9.8 5.0 0.39 9.1 3.5 1.3 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 CBZ25863.1 - 0.28 9.5 7.0 0.52 8.6 4.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) GAS PF13851.1 CBZ25863.1 - 0.38 9.9 18.4 2.2 7.4 11.6 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 CBZ25863.1 - 0.56 9.7 10.9 0.63 9.5 6.0 2.0 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 CBZ25863.1 - 0.83 9.1 20.1 7.4 6.1 0.1 3.7 2 1 2 4 4 4 0 Septum formation initiator TPR_MLP1_2 PF07926.7 CBZ25863.1 - 2.1 8.0 17.8 1.4 8.6 2.0 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 CBZ25863.1 - 2.4 8.5 13.5 17 5.8 4.7 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 CBZ25863.1 - 3.2 6.9 16.5 0.045 13.0 2.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Ly49 PF08391.5 CBZ25863.1 - 3.8 7.6 5.4 1.9 8.6 1.2 2.2 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region IncA PF04156.9 CBZ25863.1 - 4.1 6.9 22.9 36 3.8 12.9 2.9 2 1 0 2 2 2 0 IncA protein GrpE PF01025.14 CBZ25863.1 - 5.2 6.5 14.3 18 4.8 0.0 2.6 2 1 0 2 2 2 0 GrpE Kinetocho_Slk19 PF12709.2 CBZ25863.1 - 6 7.0 12.2 1.3 9.1 1.9 3.1 2 1 0 3 3 3 0 Central kinetochore-associated Paf67 PF10255.4 CBZ25864.1 - 2.8e-81 273.4 0.0 3.9e-81 273.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 FGGY_N PF00370.16 CBZ25865.1 - 6.1e-77 258.2 0.0 8.3e-77 257.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CBZ25865.1 - 1.4e-31 109.6 0.3 2.5e-31 108.8 0.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 CBZ25865.1 - 0.0034 16.7 0.0 1.1 8.5 0.0 2.9 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family DUF1609 PF07753.6 CBZ25865.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) CH PF00307.26 CBZ25866.1 - 0.0096 15.9 0.0 39 4.3 0.0 3.3 3 0 0 3 3 3 3 Calponin homology (CH) domain TFIIS_M PF07500.9 CBZ25867.1 - 0.001 19.1 1.6 0.002 18.1 1.1 1.5 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Pkinase_C PF00433.19 CBZ25867.1 - 0.54 10.8 3.0 0.91 10.0 1.3 2.0 2 0 0 2 2 2 0 Protein kinase C terminal domain NUDIX PF00293.23 CBZ25869.1 - 1.4e-14 53.9 0.0 3.8e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain DUF260 PF03195.9 CBZ25869.1 - 0.003 17.7 0.0 0.0072 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function DUF260 ESCRT-II PF05871.7 CBZ25870.1 - 6.9e-13 48.7 0.0 3.5e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 ESCRT-II complex subunit DUF3223 PF11523.3 CBZ25870.1 - 0.047 13.9 0.1 1.3 9.3 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3223) Proteasome PF00227.21 CBZ25871.1 - 3.2e-26 91.7 0.0 3.8e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RNase_HII PF01351.13 CBZ25873.1 - 2.3e-24 86.1 0.0 4.1e-15 55.9 0.0 3.0 1 1 0 2 2 2 2 Ribonuclease HII Nop10p PF04135.7 CBZ25874.1 - 1.6e-20 72.5 0.3 1.7e-20 72.4 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family IQ PF00612.22 CBZ25875.1 - 1.1 9.1 5.3 1.3 8.8 2.0 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif DUF106 PF01956.11 CBZ25876.1 - 4.1e-46 156.5 4.6 4.1e-46 156.5 3.2 1.4 2 0 0 2 2 2 1 Integral membrane protein DUF106 PIP5K PF01504.13 CBZ25877.1 - 7.8e-61 205.3 0.0 1.2e-60 204.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase ELK PF03789.8 CBZ25878.1 - 0.51 10.2 2.3 0.96 9.3 1.6 1.5 1 0 0 1 1 1 0 ELK domain Macoilin PF09726.4 CBZ25879.1 - 0.54 8.4 8.1 0.75 8.0 5.6 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF605 PF04652.11 CBZ25879.1 - 0.58 9.4 11.1 0.97 8.7 7.7 1.4 1 0 0 1 1 1 0 Vta1 like CDC45 PF02724.9 CBZ25879.1 - 6 4.7 7.0 8.1 4.3 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PDZ_2 PF13180.1 CBZ25880.1 - 5.4e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBZ25880.1 - 0.00017 21.6 0.1 0.00049 20.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) ING PF12998.2 CBZ25880.1 - 0.046 14.0 0.2 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Cor1 PF04803.7 CBZ25880.1 - 0.42 10.3 3.4 0.46 10.2 0.2 2.2 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF3391 PF11871.3 CBZ25880.1 - 0.77 9.9 6.5 0.13 12.4 0.9 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) TerB-C PF15615.1 CBZ25881.1 - 0.056 13.6 2.2 0.1 12.8 1.5 1.4 1 0 0 1 1 1 0 TerB-C domain Aa_trans PF01490.13 CBZ25882.1 - 2.3e-61 207.5 17.8 2.7e-61 207.2 12.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ25882.1 - 1.5e-06 27.2 12.5 1.5e-06 27.2 8.7 2.1 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family TFIIA_gamma_C PF02751.9 CBZ25883.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit W2 PF02020.13 CBZ25884.1 - 0.1 12.5 0.2 1.1 9.2 0.0 2.6 2 0 0 2 2 2 0 eIF4-gamma/eIF5/eIF2-epsilon FAST_1 PF06743.10 CBZ25884.1 - 0.16 11.6 1.0 7.3 6.3 0.0 3.7 4 0 0 4 4 4 0 FAST kinase-like protein, subdomain 1 YPEB PF14620.1 CBZ25885.1 - 0.17 10.8 0.2 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 YpeB sporulation Sec1 PF00995.18 CBZ25886.1 - 9.4e-130 433.9 0.2 1.1e-129 433.6 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Dus PF01207.12 CBZ25887.1 - 5.9e-36 123.8 0.7 8.6e-32 110.1 0.1 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-Apc11 PF12861.2 CBZ25888.1 - 0.018 14.8 0.8 0.032 14.0 0.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.1 CBZ25889.1 - 9e-16 57.0 6.4 2.8e-10 39.5 0.9 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 CBZ25889.1 - 0.0022 18.1 0.6 0.99 9.8 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CBZ25889.1 - 0.23 11.8 4.3 15 6.2 0.9 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CBZ25889.1 - 0.46 10.4 5.1 2.2 8.3 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CBZ25889.1 - 0.47 10.9 4.4 8.7 6.9 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Sgf11 PF08209.6 CBZ25889.1 - 1.3 8.3 4.3 2.8 7.3 0.8 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) TPR_11 PF13414.1 CBZ25890.1 - 3.5e-37 125.8 21.5 7e-19 67.2 1.8 5.4 3 2 2 5 5 5 4 TPR repeat DnaJ PF00226.26 CBZ25890.1 - 2.2e-21 75.3 2.6 5.3e-21 74.1 0.4 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 CBZ25890.1 - 7.7e-20 69.1 19.7 0.00022 20.8 0.0 8.2 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ25890.1 - 2.2e-11 43.3 20.7 0.11 13.2 0.0 7.6 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ25890.1 - 7.7e-11 42.1 15.9 0.00072 19.8 0.8 6.5 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ25890.1 - 7.8e-11 41.0 22.5 0.0019 17.7 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ25890.1 - 1.4e-10 41.5 20.3 1.6e-06 28.6 1.2 6.2 4 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ25890.1 - 2.1e-08 33.6 8.9 0.00061 19.7 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ25890.1 - 8.2e-07 28.7 13.4 0.006 16.4 0.4 5.7 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ25890.1 - 1.4e-05 24.5 13.8 0.053 13.3 0.1 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ25890.1 - 1.6e-05 24.7 17.1 0.00031 20.6 0.7 4.9 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ25890.1 - 0.00053 19.5 8.1 2.5 8.1 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat Cir_Bir_Yir PF06022.6 CBZ25890.1 - 0.054 12.7 0.3 0.1 11.7 0.2 1.5 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir DASH_Dad3 PF08656.5 CBZ25890.1 - 0.07 12.8 0.2 0.07 12.8 0.1 2.3 3 0 0 3 3 3 0 DASH complex subunit Dad3 Phage_term_smal PF05944.7 CBZ25890.1 - 0.076 12.6 2.2 2 8.0 0.2 2.7 2 0 0 2 2 2 0 Phage small terminase subunit DUF45 PF01863.12 CBZ25890.1 - 0.11 12.2 4.6 0.16 11.7 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF45 Fis1_TPR_C PF14853.1 CBZ25890.1 - 0.17 11.8 3.7 1 9.2 0.2 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 CBZ25890.1 - 1.9 7.7 6.6 15 4.9 0.2 3.4 4 0 0 4 4 4 0 SHNi-TPR Mito_carr PF00153.22 CBZ25891.1 - 3.5e-90 295.8 21.8 1.5e-21 75.8 0.0 6.4 5 1 1 6 6 6 6 Mitochondrial carrier protein PP2C PF00481.16 CBZ25893.1 - 3.3e-69 233.1 1.3 4.1e-69 232.7 0.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ25893.1 - 0.00016 21.1 0.0 0.00037 19.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CBZ25893.1 - 0.0015 18.2 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) LSM PF01423.17 CBZ25894.1 - 1.9e-07 30.5 0.1 3.1e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBZ25894.1 - 0.0018 18.1 0.9 0.0041 17.0 0.0 2.1 3 0 0 3 3 3 1 Ataxin 2 SM domain ODV-E18 PF10717.4 CBZ25895.1 - 1.1 8.7 4.1 3.9 6.9 2.1 2.1 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 ubiquitin PF00240.18 CBZ25896.1 - 8.1e-13 47.5 0.0 1.7e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 CBZ25896.1 - 2.6e-07 30.2 0.3 7.1e-07 28.8 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 CBZ25896.1 - 2.3e-05 23.9 0.1 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RNA_pol_Rpb5_C PF01191.14 CBZ25896.1 - 0.0033 16.9 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain ComX PF05952.7 CBZ25896.1 - 0.0042 16.5 1.2 0.012 15.1 0.9 1.8 1 0 0 1 1 1 1 Bacillus competence pheromone ComX XPC-binding PF09280.6 CBZ25896.1 - 0.02 14.3 18.2 0.066 12.6 12.6 1.9 1 0 0 1 1 1 0 XPC-binding domain DUF2407 PF10302.4 CBZ25896.1 - 0.029 14.5 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 CBZ25896.1 - 0.035 13.9 0.1 0.082 12.7 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ25896.1 - 0.064 13.5 0.0 0.19 11.9 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain TFIIA PF03153.8 CBZ25896.1 - 7.8 6.2 8.5 9.1 6.0 5.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.20 CBZ25897.1 - 2.5e-78 262.8 0.0 2.8e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25897.1 - 1.6e-35 122.4 0.0 3.5e-35 121.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBZ25897.1 - 0.00084 19.1 0.2 0.014 15.1 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ25897.1 - 0.068 12.5 0.0 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 CBZ25897.1 - 0.11 11.3 0.0 10 4.9 0.0 2.3 2 0 0 2 2 2 0 Kinase-like DUF641 PF04859.7 CBZ25898.1 - 0.37 10.5 13.0 0.064 13.0 2.7 2.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF972 PF06156.8 CBZ25898.1 - 0.46 10.8 21.9 0.27 11.5 1.8 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF972) PfUIS3 PF11567.3 CBZ25898.1 - 0.66 10.1 7.7 0.64 10.2 0.9 3.1 2 1 1 3 3 3 0 Plasmodium falciparum UIS3 membrane protein Reo_sigmaC PF04582.7 CBZ25898.1 - 0.68 9.0 2.6 1.5 7.9 1.7 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 CBZ25898.1 - 1.4 8.4 21.0 2.5 7.6 0.4 3.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Glutaredoxin2_C PF04399.8 CBZ25898.1 - 2 7.9 5.9 4.9 6.7 0.1 3.1 1 1 2 3 3 3 0 Glutaredoxin 2, C terminal domain ADIP PF11559.3 CBZ25898.1 - 2.4 8.0 32.3 3.7 7.4 0.8 4.3 1 1 4 5 5 5 0 Afadin- and alpha -actinin-Binding GTP_EFTU PF00009.22 CBZ25899.1 - 1.1e-59 201.0 0.0 2e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CBZ25899.1 - 2e-23 81.9 0.0 4.8e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CBZ25899.1 - 1.7e-20 72.6 0.0 4.2e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 CBZ25899.1 - 7.6e-16 57.7 0.0 1.8e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 CBZ25899.1 - 4.3e-07 29.9 0.2 2.4e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 AIG1 PF04548.11 CBZ25899.1 - 0.014 14.4 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 AIG1 family MMR_HSR1 PF01926.18 CBZ25899.1 - 0.023 14.6 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF442 PF04273.8 CBZ25899.1 - 0.041 13.7 0.0 2.3 8.1 0.0 2.9 3 0 0 3 3 3 0 Putative phosphatase (DUF442) FeoB_N PF02421.13 CBZ25899.1 - 0.063 12.5 0.1 0.75 9.0 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B WD40 PF00400.27 CBZ25900.1 - 8.2e-13 47.7 5.6 7.5e-05 22.4 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat CRAL_TRIO PF00650.15 CBZ25901.1 - 4.1e-25 88.1 0.0 6.8e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CAP_GLY PF01302.20 CBZ25901.1 - 1.5e-12 47.0 0.5 2.6e-12 46.2 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain IF4E PF01652.13 CBZ25902.1 - 1.7e-08 34.1 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S27 PF01599.14 CBZ25903.1 - 1.5e-20 72.7 3.5 3.1e-20 71.7 2.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CBZ25903.1 - 1.1e-07 31.4 0.0 1.1e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBZ25903.1 - 4.8e-07 29.0 0.0 1.3e-05 24.4 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin family IBR PF01485.16 CBZ25903.1 - 0.0022 17.7 0.8 0.0037 17.1 0.6 1.4 1 0 0 1 1 1 1 IBR domain DnaJ PF00226.26 CBZ25904.1 - 7e-23 80.1 0.6 1.4e-22 79.1 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain ATP-synt_Eps PF04627.8 CBZ25905.1 - 3.7e-06 26.3 0.1 5.2e-06 25.9 0.1 1.5 1 1 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF3592 PF12158.3 CBZ25906.1 - 5.8e-13 48.8 0.7 6.7e-13 48.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) RNase_HII PF01351.13 CBZ25907.1 - 5.1e-32 111.1 0.0 6.6e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII PIG-U PF06728.8 CBZ25908.1 - 6.9e-06 25.1 21.2 4e-05 22.6 14.7 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Cys_rich_FGFR PF00839.12 CBZ25909.1 - 0.32 10.9 1.6 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 Cysteine rich repeat EamA PF00892.15 CBZ25910.1 - 1.1e-06 28.6 30.0 0.00015 21.8 4.0 4.5 5 0 0 5 5 5 2 EamA-like transporter family Nuc_sug_transp PF04142.10 CBZ25910.1 - 0.00099 18.2 0.3 0.00099 18.2 0.2 2.2 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 CBZ25910.1 - 0.011 15.8 5.1 0.011 15.8 3.5 3.9 5 0 0 5 5 5 0 Multidrug resistance efflux transporter TPT PF03151.11 CBZ25910.1 - 0.066 12.8 22.0 0.027 14.1 6.5 2.8 2 2 0 2 2 2 0 Triose-phosphate Transporter family SSB PF00436.20 CBZ25913.1 - 1.8e-05 24.5 0.0 2.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.20 CBZ25913.1 - 0.046 13.5 0.0 0.095 12.5 0.0 1.6 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain LRR_4 PF12799.2 CBZ25914.1 - 1.8e-13 49.7 0.2 1.6e-05 24.4 0.0 3.1 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBZ25914.1 - 1.1e-08 34.8 0.0 2.2e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CBZ25914.1 - 2.5e-07 30.3 1.1 2.3e-05 24.0 0.1 2.6 1 1 1 2 2 2 2 Leucine rich repeat BBIP10 PF14777.1 CBZ25914.1 - 0.033 13.5 1.2 0.081 12.3 0.8 1.6 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 LRR_1 PF00560.28 CBZ25914.1 - 0.055 13.5 0.3 47 4.5 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 CBZ25914.1 - 0.059 13.5 2.0 1.3e+02 3.4 0.0 4.9 5 0 0 5 5 5 0 Leucine rich repeat tRNA_bind_2 PF13725.1 CBZ25914.1 - 0.084 12.9 0.3 0.51 10.4 0.0 2.2 2 1 1 3 3 3 0 Possible tRNA binding domain DUF1180 PF06679.7 CBZ25914.1 - 0.13 12.1 1.4 0.2 11.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pkinase PF00069.20 CBZ25915.1 - 4.7e-71 238.9 0.0 5.8e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25915.1 - 1.7e-34 119.1 0.0 2.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25915.1 - 0.00066 18.7 0.0 0.0012 17.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ25915.1 - 0.02 14.6 0.1 0.048 13.3 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CBZ25915.1 - 0.033 13.2 1.2 0.065 12.2 0.8 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH_2 PF14608.1 CBZ25916.1 - 0.0032 17.4 2.3 1 9.4 0.2 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 CBZ25916.1 - 0.1 12.2 17.0 0.11 12.2 0.2 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH PF00642.19 CBZ25917.1 - 3.2 7.5 6.9 0.18 11.5 0.7 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) XPC-binding PF09280.6 CBZ25918.1 - 0.0059 16.0 0.0 0.0059 16.0 0.0 2.1 3 0 0 3 3 3 1 XPC-binding domain BUD22 PF09073.5 CBZ25918.1 - 2.1 7.3 6.6 3.5 6.6 4.6 1.3 1 0 0 1 1 1 0 BUD22 TPR_11 PF13414.1 CBZ25919.1 - 2.2e-22 78.4 7.8 3.1e-12 45.9 0.1 6.2 4 3 2 7 7 7 3 TPR repeat TPR_1 PF00515.23 CBZ25919.1 - 4.8e-13 48.1 10.9 1.4e-05 24.4 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ25919.1 - 1e-11 43.8 28.6 0.0015 18.3 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat DnaJ PF00226.26 CBZ25919.1 - 5.2e-09 35.7 0.7 1.4e-08 34.2 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_7 PF13176.1 CBZ25919.1 - 1.1e-05 24.8 5.1 0.31 10.9 0.1 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ25919.1 - 9.3e-05 22.2 26.1 0.28 11.0 0.3 6.0 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ25919.1 - 0.00011 22.0 19.1 0.014 15.2 2.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ25919.1 - 0.00047 19.7 1.3 9.2 6.3 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ25919.1 - 0.00092 19.6 38.2 0.032 14.8 0.1 7.8 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ25919.1 - 0.0074 16.4 7.2 8.3 6.8 0.0 4.9 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ25919.1 - 1 10.1 38.4 0.53 11.0 0.7 6.1 3 2 3 6 6 6 0 Tetratricopeptide repeat TFIIE-A_C-term PF11521.3 CBZ25920.1 - 1.1 9.2 4.4 0.86 9.5 0.5 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Peptidase_C2 PF00648.16 CBZ25921.1 - 8.1e-19 67.7 0.0 1.6e-18 66.7 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease Tfb2 PF03849.9 CBZ25923.1 - 2.1e-20 72.6 0.0 4.7e-20 71.5 0.0 1.5 1 1 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CBZ25923.1 - 5.4e-09 35.8 0.1 9.8e-07 28.5 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Arf PF00025.16 CBZ25925.1 - 3.3e-30 104.6 0.0 4.7e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CBZ25925.1 - 2.3e-09 36.4 0.0 1.2e-08 34.0 0.0 2.1 2 1 1 3 3 3 1 G-protein alpha subunit Ras PF00071.17 CBZ25925.1 - 2.3e-08 33.6 0.0 3.5e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Ras family SRPRB PF09439.5 CBZ25925.1 - 1.2e-05 24.5 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cNMP_binding PF00027.24 CBZ25926.1 - 1.3e-21 76.1 0.0 1.3e-12 47.3 0.0 4.0 3 1 0 3 3 3 2 Cyclic nucleotide-binding domain C2 PF00168.25 CBZ25926.1 - 6e-08 32.4 0.0 0.00011 21.9 0.0 3.2 3 0 0 3 3 3 2 C2 domain zf-CCCH PF00642.19 CBZ25927.1 - 0.019 14.6 11.0 0.3 10.8 0.2 3.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mvb12 PF09452.5 CBZ25927.1 - 0.096 12.8 0.2 0.19 11.9 0.2 1.4 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 LRV_FeS PF05484.6 CBZ25927.1 - 0.2 11.2 7.2 0.61 9.7 0.9 2.6 2 0 0 2 2 2 0 LRV protein FeS4 cluster C2 PF00168.25 CBZ25928.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 C2 domain DivIC PF04977.10 CBZ25928.1 - 1.4 8.4 7.7 0.94 9.0 0.2 2.7 2 1 0 2 2 2 0 Septum formation initiator Pkinase PF00069.20 CBZ25929.1 - 4.3e-54 183.3 0.0 5.6e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25929.1 - 1.6e-31 109.3 0.0 2.2e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ25929.1 - 0.018 14.7 0.1 0.22 11.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ25929.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HA2 PF04408.18 CBZ25930.1 - 2.7e-18 65.8 0.0 6.4e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBZ25930.1 - 2.6e-15 56.0 0.0 9.1e-15 54.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ25930.1 - 4.3e-09 36.1 0.0 1.5e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ25930.1 - 0.00053 20.1 0.4 0.0061 16.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CBZ25930.1 - 0.0019 17.1 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 CBZ25930.1 - 0.014 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 CBZ25930.1 - 0.016 14.8 0.1 0.33 10.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 CBZ25930.1 - 0.017 14.8 2.5 0.058 13.1 0.0 3.1 3 1 0 3 3 3 0 Part of AAA domain AAA_23 PF13476.1 CBZ25930.1 - 0.026 14.8 0.1 0.065 13.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CBZ25930.1 - 0.034 14.2 0.0 0.23 11.5 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain PhoH PF02562.11 CBZ25930.1 - 0.056 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 CBZ25930.1 - 0.059 13.6 0.1 0.18 12.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain ResIII PF04851.10 CBZ25930.1 - 0.075 12.8 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_10 PF12846.2 CBZ25930.1 - 0.077 12.4 0.0 2.9 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain Sigma54_activat PF00158.21 CBZ25930.1 - 0.082 12.3 0.0 0.66 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain OB_NTP_bind PF07717.11 CBZ25930.1 - 0.083 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 CBZ25930.1 - 0.099 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CBZ25930.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 CBZ25930.1 - 0.12 11.2 0.0 0.97 8.2 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain Miro PF08477.8 CBZ25930.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein HTH_32 PF13565.1 CBZ25930.1 - 0.16 12.7 1.3 33 5.3 0.0 3.1 2 0 0 2 2 2 0 Homeodomain-like domain NifU PF01106.12 CBZ25931.1 - 9.2e-20 70.1 0.1 2.5e-19 68.8 0.1 1.8 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 CBZ25931.1 - 1.8e-07 30.6 0.0 5.9e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal eIF-6 PF01912.13 CBZ25932.1 - 4e-81 270.8 0.8 4.5e-81 270.7 0.2 1.3 2 0 0 2 2 2 1 eIF-6 family Pkinase PF00069.20 CBZ25933.1 - 3.4e-71 239.4 0.0 4.7e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25933.1 - 9.7e-39 132.9 0.0 1.4e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25933.1 - 3.5e-07 29.4 0.0 5.7e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBZ25933.1 - 0.00021 20.6 0.2 0.00035 19.9 0.2 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CBZ25933.1 - 0.0012 17.9 0.1 0.0024 16.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ25933.1 - 0.0025 17.6 0.1 1.2 8.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ25933.1 - 0.0091 15.3 0.1 0.016 14.5 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 CBZ25934.1 - 1.6e-51 175.0 0.0 2.5e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25934.1 - 3.4e-30 104.9 0.0 5.4e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ25934.1 - 0.0015 18.2 0.0 0.004 16.9 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family ETRAMP PF09716.5 CBZ25934.1 - 0.041 13.8 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ribonuclease_3 PF00636.21 CBZ25935.1 - 0.038 14.4 0.0 0.58 10.6 0.0 2.5 1 1 0 1 1 1 0 Ribonuclease III domain Ribosomal_S13 PF00416.17 CBZ25936.1 - 4.2e-31 107.5 0.2 5e-31 107.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF4004 PF13171.1 CBZ25936.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) Ribosomal_S13 PF00416.17 CBZ25937.1 - 4.2e-31 107.5 0.2 5e-31 107.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DUF4004 PF13171.1 CBZ25937.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) Dynein_heavy PF03028.10 CBZ25938.1 - 2.9e-214 713.1 0.0 2.9e-214 713.1 0.0 3.6 4 0 0 4 4 3 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ25938.1 - 1.7e-125 418.7 12.9 1.7e-125 418.7 8.9 3.6 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ25938.1 - 2.2e-91 305.4 0.1 1.2e-90 303.0 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ25938.1 - 1.2e-69 234.2 0.1 2.8e-69 233.0 0.1 1.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ25938.1 - 1.5e-54 184.2 0.1 3.2e-54 183.1 0.1 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CBZ25938.1 - 4.4e-44 150.6 11.4 8.8e-44 149.6 7.9 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBZ25938.1 - 2.9e-37 128.2 0.0 5.5e-37 127.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBZ25938.1 - 4.2e-15 55.6 0.6 0.0001 22.0 0.0 7.3 7 2 0 7 7 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ25938.1 - 1.3e-09 38.2 0.0 1.6e-05 25.0 0.0 4.3 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 CBZ25938.1 - 8e-06 25.9 0.0 0.07 13.3 0.0 4.0 4 0 0 4 4 3 2 RNA helicase AAA PF00004.24 CBZ25938.1 - 1.8e-05 24.9 0.0 0.34 11.0 0.0 3.7 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CBZ25938.1 - 5.9e-05 22.7 0.0 0.015 14.9 0.0 3.6 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 CBZ25938.1 - 0.00072 19.5 9.9 0.52 10.2 0.0 5.9 6 1 1 7 7 5 2 AAA ATPase domain AAA_10 PF12846.2 CBZ25938.1 - 0.00084 18.8 2.8 0.17 11.3 0.0 4.2 5 0 0 5 5 4 1 AAA-like domain AAA_14 PF13173.1 CBZ25938.1 - 0.0009 19.1 0.0 2.2 8.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CBZ25938.1 - 0.0081 15.8 1.0 0.66 9.7 0.1 3.5 3 0 0 3 3 3 1 Part of AAA domain AAA_18 PF13238.1 CBZ25938.1 - 0.018 15.3 0.0 4.1 7.7 0.0 4.2 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 CBZ25938.1 - 0.024 14.1 2.5 3.4 7.0 0.0 3.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_17 PF13207.1 CBZ25938.1 - 0.034 14.9 0.0 7.4 7.4 0.0 3.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CBZ25938.1 - 0.12 11.9 0.0 13 5.1 0.0 2.9 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IncA PF04156.9 CBZ25938.1 - 1 8.8 37.6 0.0096 15.5 2.7 4.3 3 0 0 3 3 3 0 IncA protein AAA_25 PF13481.1 CBZ25938.1 - 3.7 6.9 10.4 5 6.4 0.0 4.4 5 0 0 5 5 5 0 AAA domain Gp58 PF07902.6 CBZ25938.1 - 5.2 5.1 6.2 0.24 9.5 0.4 1.5 2 0 0 2 2 2 0 gp58-like protein Claudin_2 PF13903.1 CBZ25939.1 - 0.89 9.2 18.2 3.5 7.2 2.8 3.6 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction CBM_4_9 PF02018.12 CBZ25940.1 - 0.051 13.5 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain S10_plectin PF03501.10 CBZ25941.1 - 3e-34 116.7 0.0 3.8e-34 116.4 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain API5 PF05918.6 CBZ25941.1 - 4 5.8 15.3 5.9 5.2 10.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) S10_plectin PF03501.10 CBZ25942.1 - 3.1e-34 116.6 0.0 3.8e-34 116.4 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain API5 PF05918.6 CBZ25942.1 - 4 5.8 15.3 5.9 5.2 10.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.27 CBZ25943.1 - 4.2e-17 61.3 16.8 5.5e-11 41.8 0.3 8.0 9 0 0 9 9 9 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBZ25943.1 - 1.3e-06 27.4 0.0 0.00093 18.1 0.0 3.9 3 1 1 4 4 4 1 Coatomer WD associated region Clathrin PF00637.15 CBZ25943.1 - 1.3e-05 24.7 1.8 0.0098 15.4 0.0 3.6 2 1 2 4 4 4 2 Region in Clathrin and VPS TPR_7 PF13176.1 CBZ25943.1 - 0.019 14.7 3.5 5.7 6.9 0.0 4.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ25943.1 - 0.056 13.3 9.8 9.5 6.4 0.2 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat CPSF_A PF03178.10 CBZ25943.1 - 0.11 11.5 0.2 26 3.7 0.1 3.4 3 1 0 3 3 3 0 CPSF A subunit region TPR_14 PF13428.1 CBZ25943.1 - 1.1 10.0 12.5 25 5.8 0.4 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ25943.1 - 4.7 6.9 9.6 38 4.1 0.2 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat LOH1CR12 PF10158.4 CBZ25944.1 - 0.0078 16.0 1.1 0.02 14.7 0.8 1.7 1 0 0 1 1 1 1 Tumour suppressor protein DUF3330 PF11809.3 CBZ25944.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) CLAMP PF14769.1 CBZ25947.1 - 3.6e-29 100.8 1.8 7e-29 99.9 1.2 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Ribonuclease_3 PF00636.21 CBZ25948.1 - 0.01 16.2 0.0 0.065 13.6 0.0 2.2 1 1 0 1 1 1 0 Ribonuclease III domain DDT PF02791.12 CBZ25949.1 - 9.8e-05 22.0 0.1 0.00022 20.9 0.1 1.6 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 CBZ25949.1 - 0.0011 18.8 0.1 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Neur_chan_memb PF02932.11 CBZ25949.1 - 3.1 7.6 5.3 27 4.5 0.1 2.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_L24e PF01246.15 CBZ25950.1 - 8e-15 54.4 0.5 8e-15 54.4 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e DUF4189 PF13827.1 CBZ25952.1 - 0.011 15.9 1.2 0.029 14.5 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4189) Ribosomal_L24e PF01246.15 CBZ25953.1 - 8e-15 54.4 0.5 8e-15 54.4 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e HORMA PF02301.13 CBZ25954.1 - 4e-47 160.4 0.0 5.2e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 HORMA domain IL22 PF14565.1 CBZ25956.1 - 0.11 12.5 0.0 5.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor 3HCDH_N PF02737.13 CBZ25957.1 - 1.2e-56 191.2 1.7 1.5e-56 190.9 1.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 CBZ25957.1 - 2.9e-34 117.3 0.0 7.4e-34 116.0 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBZ25957.1 - 0.0065 16.3 1.3 0.07 12.9 0.9 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 CBZ25957.1 - 0.0084 15.8 1.5 0.019 14.7 1.1 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 CBZ25957.1 - 0.076 13.4 0.1 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Memo PF01875.12 CBZ25959.1 - 2.4e-61 207.0 0.0 3.3e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein CorA PF01544.13 CBZ25960.1 - 0.00021 20.4 0.1 0.00074 18.6 0.0 1.8 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Abhydrolase_9 PF10081.4 CBZ25962.1 - 0.026 13.2 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family COQ7 PF03232.8 CBZ25962.1 - 0.078 12.4 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 OTCace PF00185.19 CBZ25962.1 - 0.11 12.3 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Glyco_transf_22 PF03901.12 CBZ25963.1 - 1.3e-70 238.4 25.5 1.7e-70 238.1 17.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PP2C PF00481.16 CBZ25966.1 - 2.4e-09 36.9 0.0 4.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Ribosomal_S4 PF00163.14 CBZ25968.1 - 7.2e-29 100.0 0.4 1.5e-28 99.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CBZ25968.1 - 5.8e-14 51.2 0.4 1.3e-13 50.1 0.3 1.6 1 0 0 1 1 1 1 S4 domain Glycolytic PF00274.14 CBZ25969.1 - 2.4e-144 480.0 0.0 2.7e-144 479.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I eIF-3_zeta PF05091.7 CBZ25969.1 - 0.19 10.3 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Amastin PF07344.6 CBZ25971.1 - 1.4e-51 174.1 12.1 1.8e-51 173.8 8.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ25971.1 - 0.58 9.8 20.8 0.023 14.3 9.0 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 CBZ25971.1 - 5.8 7.0 10.6 14 5.8 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3094 PF11293.3 CBZ25972.1 - 0.013 14.9 1.2 0.91 9.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) SIP1 PF04938.7 CBZ25973.1 - 0.0025 17.2 0.0 0.0055 16.0 0.0 1.6 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) APG6 PF04111.7 CBZ25974.1 - 0.051 12.6 6.0 0.075 12.0 4.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 SOBP PF15279.1 CBZ25974.1 - 0.18 12.1 2.1 0.23 11.8 1.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2948 PF11164.3 CBZ25974.1 - 0.79 9.3 4.2 1.4 8.5 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2948) GAS PF13851.1 CBZ25974.1 - 2.5 7.2 9.1 3.6 6.7 6.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CorA PF01544.13 CBZ25974.1 - 4.7 6.1 5.9 7.5 5.4 4.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RdRP PF05183.7 CBZ25975.1 - 0.078 11.6 0.0 0.099 11.3 0.0 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase Filament PF00038.16 CBZ25975.1 - 0.83 9.0 4.2 1.6 8.0 1.0 2.4 3 0 0 3 3 3 0 Intermediate filament protein Harakiri PF15196.1 CBZ25975.1 - 3.6 7.9 10.1 1.3 9.2 0.7 3.7 3 1 1 4 4 4 0 Activator of apoptosis harakiri DnaJ PF00226.26 CBZ25976.1 - 5.6e-10 38.8 0.0 1.1e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3278 PF11683.3 CBZ25976.1 - 0.26 11.2 1.2 0.41 10.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) NARP1 PF12569.3 CBZ25977.1 - 7.7e-87 292.1 15.8 2.4e-83 280.6 7.9 2.4 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 CBZ25977.1 - 2e-18 65.7 15.5 2.8e-05 23.6 0.0 6.2 6 1 0 6 6 6 3 TPR repeat TPR_2 PF07719.12 CBZ25977.1 - 1.4e-12 46.5 18.3 0.00026 20.6 0.0 8.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ25977.1 - 2.2e-10 40.1 19.6 0.13 13.0 0.0 8.0 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ25977.1 - 3.8e-10 38.9 11.2 7.3e-05 22.2 0.0 6.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ25977.1 - 2.2e-08 34.5 21.4 0.0014 19.2 0.0 7.2 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ25977.1 - 6.7e-08 32.7 12.9 0.024 14.9 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ25977.1 - 1.4e-07 31.2 4.0 0.00059 19.6 0.0 4.5 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ25977.1 - 2.3e-07 30.4 6.4 0.92 9.8 0.0 6.5 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ25977.1 - 8.8e-07 28.2 1.4 0.32 10.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ25977.1 - 4e-06 26.6 14.8 0.073 13.0 1.3 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ25977.1 - 0.0037 17.1 0.9 18 5.2 0.0 4.4 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 CBZ25977.1 - 0.0085 15.8 13.0 1.4 8.8 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat DUF1771 PF08590.5 CBZ25977.1 - 9.7 6.2 11.7 0.95 9.5 1.9 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1771) zf-PARP PF00645.13 CBZ25978.1 - 1.6e-21 76.3 0.9 1.6e-21 76.3 0.6 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.4 CBZ25978.1 - 1.3e-12 47.2 5.7 2.1e-12 46.6 3.9 1.3 1 0 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif ADK PF00406.17 CBZ25979.1 - 1.9e-42 144.6 0.0 3e-42 144.0 0.0 1.3 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.1 CBZ25979.1 - 2.3e-11 44.5 0.0 6.9e-11 43.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ25979.1 - 2.7e-11 43.8 0.2 2.7e-10 40.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 CBZ25979.1 - 1.8e-06 27.8 0.8 0.00011 22.0 0.5 2.8 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.9 CBZ25979.1 - 3.7e-05 23.3 0.0 7.7e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA PF00004.24 CBZ25979.1 - 0.0043 17.2 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CBZ25979.1 - 0.011 14.8 0.2 0.021 13.9 0.0 1.8 2 1 0 2 2 2 0 Zeta toxin SKI PF01202.17 CBZ25979.1 - 0.037 13.9 0.8 7.5 6.3 0.5 3.0 2 1 0 2 2 2 0 Shikimate kinase RuvB_N PF05496.7 CBZ25979.1 - 0.039 12.9 0.3 0.09 11.8 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Thymidylate_kin PF02223.12 CBZ25979.1 - 0.077 12.3 1.0 3.7 6.8 0.4 2.8 2 1 0 2 2 2 0 Thymidylate kinase ABC_tran PF00005.22 CBZ25979.1 - 0.089 13.0 0.2 3.2 8.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA PF00004.24 CBZ25980.1 - 4.1e-96 318.2 0.0 5.2e-47 159.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CBZ25980.1 - 4.3e-22 77.8 0.2 1.9e-21 75.7 0.1 2.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.1 CBZ25980.1 - 5e-14 53.1 0.0 4.6e-05 24.2 0.0 3.8 3 1 0 3 3 3 2 AAA domain RuvB_N PF05496.7 CBZ25980.1 - 2.8e-13 49.4 0.0 1.3e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBZ25980.1 - 8.6e-13 48.6 0.1 4.5e-05 23.5 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain AAA_2 PF07724.9 CBZ25980.1 - 3.6e-12 46.5 0.0 2e-06 27.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CBZ25980.1 - 4.7e-12 45.9 0.0 5.2e-06 26.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CBZ25980.1 - 9.8e-12 45.1 0.3 0.00034 20.7 0.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBZ25980.1 - 7.5e-11 41.9 0.2 5.9e-05 22.8 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.12 CBZ25980.1 - 6.8e-10 38.4 0.0 1.5e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 CBZ25980.1 - 2.8e-09 36.9 0.0 0.0007 19.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CBZ25980.1 - 3.9e-09 35.8 0.0 0.0018 17.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 CBZ25980.1 - 9.6e-09 34.4 0.1 0.00029 19.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 CBZ25980.1 - 7.5e-08 32.7 0.0 0.006 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CBZ25980.1 - 1.7e-07 31.4 0.0 0.0041 17.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 CBZ25980.1 - 1.7e-07 30.8 2.8 0.02 14.3 0.1 4.0 2 2 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBZ25980.1 - 2.5e-07 30.2 0.0 0.012 15.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 CBZ25980.1 - 4.5e-07 29.2 0.2 0.027 13.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 CBZ25980.1 - 5.5e-07 29.5 0.2 1.2 8.7 0.0 3.5 2 2 1 3 3 3 3 Archaeal ATPase AAA_19 PF13245.1 CBZ25980.1 - 1.4e-06 27.9 1.0 0.035 13.8 0.2 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 CBZ25980.1 - 3.7e-06 26.9 0.0 0.16 11.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 CBZ25980.1 - 4.9e-06 26.5 0.0 0.0014 18.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.7 CBZ25980.1 - 7.5e-06 25.6 0.1 0.15 11.6 0.0 3.7 3 1 0 4 4 4 2 NACHT domain Sigma54_activ_2 PF14532.1 CBZ25980.1 - 7.7e-06 25.9 0.0 0.028 14.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 CBZ25980.1 - 1.4e-05 25.3 0.0 0.044 14.0 0.0 3.0 2 1 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.12 CBZ25980.1 - 3e-05 23.0 0.0 0.046 12.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Vps4_C PF09336.5 CBZ25980.1 - 4e-05 23.4 0.0 0.00045 20.0 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Bac_DnaA PF00308.13 CBZ25980.1 - 5e-05 23.0 0.0 0.083 12.5 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein KaiC PF06745.8 CBZ25980.1 - 5.7e-05 22.3 1.3 1.5 7.9 0.0 3.6 2 1 1 3 3 3 1 KaiC AAA_24 PF13479.1 CBZ25980.1 - 6.2e-05 22.6 0.0 0.33 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CBZ25980.1 - 6.6e-05 22.4 0.0 0.4 10.1 0.0 3.3 2 1 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CBZ25980.1 - 0.00011 21.8 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 CBZ25980.1 - 0.00026 19.9 0.1 0.57 8.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_3 PF07726.6 CBZ25980.1 - 0.00026 20.5 0.0 0.91 9.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CBZ25980.1 - 0.0012 18.1 0.2 0.71 9.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein NTPase_1 PF03266.10 CBZ25980.1 - 0.0018 17.9 1.1 2.6 7.7 0.0 3.8 3 1 1 4 4 4 0 NTPase Cytidylate_kin2 PF13189.1 CBZ25980.1 - 0.0025 17.7 0.0 0.26 11.2 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family DUF2075 PF09848.4 CBZ25980.1 - 0.0031 16.5 0.0 0.89 8.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) SKI PF01202.17 CBZ25980.1 - 0.0039 17.0 0.0 3.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.1 CBZ25980.1 - 0.0058 16.9 0.1 5.6 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Molydop_binding PF01568.16 CBZ25980.1 - 0.0082 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain UPF0079 PF02367.12 CBZ25980.1 - 0.011 15.3 0.4 6.4 6.4 0.0 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 CBZ25980.1 - 0.011 15.1 0.3 4.1 6.7 0.0 3.4 3 1 0 4 4 4 0 AAA-like domain DUF815 PF05673.8 CBZ25980.1 - 0.016 14.1 0.0 4.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) T2SE PF00437.15 CBZ25980.1 - 0.017 14.0 0.0 9.2 5.0 0.0 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein DEAD PF00270.24 CBZ25980.1 - 0.02 14.3 0.3 9.1 5.7 0.0 3.4 3 1 1 4 4 3 0 DEAD/DEAH box helicase Zot PF05707.7 CBZ25980.1 - 0.042 13.3 0.3 4.1 6.8 0.1 3.3 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) KTI12 PF08433.5 CBZ25980.1 - 0.047 12.8 0.1 8.5 5.4 0.0 2.5 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 CBZ25980.1 - 0.053 13.0 0.0 8.9 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain TEX19 PF15553.1 CBZ25980.1 - 0.054 13.3 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 KAP_NTPase PF07693.9 CBZ25980.1 - 0.058 12.3 0.2 3.4 6.5 0.0 3.1 2 2 1 3 3 3 0 KAP family P-loop domain AAA_21 PF13304.1 CBZ25980.1 - 0.064 13.2 0.5 25 4.7 0.4 3.1 2 1 0 2 2 2 0 AAA domain CPT PF07931.7 CBZ25980.1 - 0.084 12.4 0.0 3.1 7.4 0.0 2.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ATP-synt_ab PF00006.20 CBZ25980.1 - 0.086 12.3 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 CBZ25980.1 - 0.097 12.2 0.0 7.3 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain eIF-1a PF01176.14 CBZ25980.1 - 0.1 12.0 1.2 2.3 7.7 0.0 2.9 3 0 0 3 3 2 0 Translation initiation factor 1A / IF-1 AAA_30 PF13604.1 CBZ25980.1 - 0.14 11.7 0.0 20 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 CBZ25980.1 - 0.17 10.6 0.0 11 4.7 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase DAP3 PF10236.4 CBZ25980.1 - 0.22 10.4 0.0 17 4.2 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Trypsin_2 PF13365.1 CBZ25981.1 - 4.3e-06 26.7 0.0 7.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF3819 PF12842.2 CBZ25981.1 - 0.063 12.9 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3819) DUF755 PF05501.6 CBZ25982.1 - 0.01 15.8 5.2 0.032 14.2 3.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF755) TMF_TATA_bd PF12325.3 CBZ25982.1 - 0.038 13.7 6.8 0.88 9.3 1.5 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding zf-Dof PF02701.10 CBZ25982.1 - 0.075 12.9 1.6 0.18 11.7 1.1 1.6 1 0 0 1 1 1 0 Dof domain, zinc finger ARL2_Bind_BART PF11527.3 CBZ25984.1 - 3.5e-36 123.6 1.8 3.5e-36 123.6 1.2 1.8 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART UIM PF02809.15 CBZ25984.1 - 0.0028 17.0 0.0 0.0028 17.0 0.0 4.3 5 0 0 5 5 5 1 Ubiquitin interaction motif UBA PF00627.26 CBZ25984.1 - 0.03 14.1 0.1 0.095 12.5 0.1 1.9 1 0 0 1 1 1 0 UBA/TS-N domain zf-RanBP PF00641.13 CBZ25986.1 - 1e-16 59.7 83.3 8.3e-09 34.4 2.0 9.3 9 0 0 9 9 9 7 Zn-finger in Ran binding protein and others DZR PF12773.2 CBZ25986.1 - 3.8e-06 26.6 72.7 0.0032 17.2 4.6 7.2 3 2 5 8 8 8 8 Double zinc ribbon EF1_GNE PF00736.14 CBZ25987.1 - 1.9e-29 101.1 1.3 3.1e-29 100.5 0.9 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Chorein_N PF12624.2 CBZ25988.1 - 2.4e-24 85.1 0.1 5.4e-11 42.0 0.0 2.5 2 0 0 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF2051 PF09738.4 CBZ25988.1 - 6.8 5.8 1.4 12 5.0 1.0 1.3 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) TraE PF05309.6 CBZ25989.1 - 0.0083 15.2 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 TraE protein HECT PF00632.20 CBZ25989.1 - 0.051 12.7 0.0 0.064 12.3 0.0 1.1 1 0 0 1 1 1 0 HECT-domain (ubiquitin-transferase) DUF2968 PF11180.3 CBZ25990.1 - 0.74 9.1 5.6 0.88 8.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Kelch_1 PF01344.20 CBZ25991.1 - 1.7e-18 65.8 0.6 2.7e-07 30.0 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBZ25991.1 - 1e-15 57.2 2.4 3e-07 30.0 0.0 5.7 6 1 1 7 7 7 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CBZ25991.1 - 1.1e-15 57.3 0.4 7.5e-07 29.1 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBZ25991.1 - 8.7e-14 51.0 2.2 1.3e-05 25.1 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBZ25991.1 - 9.8e-10 37.8 0.3 7.7e-06 25.4 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CBZ25991.1 - 3.6e-09 36.3 4.8 0.0022 17.8 0.0 4.5 4 0 0 4 4 4 2 Kelch motif TetR_C PF02909.12 CBZ25994.1 - 0.082 12.5 0.1 11 5.6 0.0 3.0 3 0 0 3 3 3 0 Tetracyclin repressor, C-terminal all-alpha domain DUF4392 PF14336.1 CBZ25995.1 - 0.0057 15.4 0.2 0.0089 14.8 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4392) DUF4515 PF14988.1 CBZ25995.1 - 0.037 13.7 2.9 0.051 13.2 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Fib_alpha PF08702.5 CBZ25995.1 - 0.054 13.6 0.7 0.088 12.9 0.5 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PilJ PF13675.1 CBZ25995.1 - 0.059 13.6 0.3 0.097 12.9 0.2 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4363 PF14276.1 CBZ25995.1 - 0.067 12.8 0.7 0.13 12.0 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4363) Spectrin PF00435.16 CBZ25995.1 - 0.092 13.0 3.8 0.12 12.6 0.4 2.4 1 1 1 2 2 2 0 Spectrin repeat PIG-P PF08510.7 CBZ25995.1 - 0.13 11.9 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 PIG-P Allexi_40kDa PF05549.6 CBZ25995.1 - 0.3 10.3 1.9 0.65 9.2 0.0 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein Tup_N PF08581.5 CBZ25995.1 - 0.73 10.0 3.6 1.6 8.9 2.5 1.8 1 1 0 1 1 1 0 Tup N-terminal Pkinase PF00069.20 CBZ25996.1 - 1.7e-54 184.7 0.0 2.5e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25996.1 - 3.3e-35 121.4 0.0 5.4e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25996.1 - 2e-06 26.9 0.0 3.8e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like PH PF00169.24 CBZ25996.1 - 6.1e-05 23.1 0.1 0.00013 22.1 0.1 1.6 1 1 0 1 1 1 1 PH domain PH_9 PF15410.1 CBZ25996.1 - 0.029 14.5 0.2 0.11 12.6 0.1 2.0 2 1 0 2 2 2 0 Pleckstrin homology domain PH_4 PF15404.1 CBZ25996.1 - 0.034 13.6 0.1 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain PH_2 PF08458.5 CBZ25996.1 - 0.078 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_11 PF15413.1 CBZ25996.1 - 0.095 12.9 0.1 0.26 11.5 0.0 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.20 CBZ25997.1 - 3.8e-54 183.5 0.0 5.1e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ25997.1 - 2.5e-35 121.7 0.0 3.9e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ25997.1 - 1.8e-08 33.7 0.0 2.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 CBZ25997.1 - 0.00015 21.9 0.0 0.0013 18.9 0.0 2.3 1 1 0 1 1 1 1 PH domain ELMO_CED12 PF04727.8 CBZ25998.1 - 1.2e-38 132.3 0.0 1.7e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family zf-B_box PF00643.19 CBZ25999.1 - 4.7e-08 32.7 8.1 4.7e-08 32.7 5.6 3.9 4 0 0 4 4 4 2 B-box zinc finger LRR_4 PF12799.2 CBZ26000.1 - 5.3e-21 73.7 4.4 1.9e-05 24.1 0.0 5.5 4 2 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ26000.1 - 2.2e-16 59.3 8.2 3.2e-07 30.0 0.1 4.2 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 CBZ26000.1 - 6.9e-08 31.7 7.3 12 6.3 0.1 7.4 7 1 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.28 CBZ26000.1 - 1.9e-07 30.1 17.6 4.1 7.8 0.8 8.7 7 2 1 8 8 8 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ26000.1 - 4.6e-06 25.9 19.5 4.4 7.9 0.3 8.4 7 1 0 7 7 7 2 Leucine rich repeat LRR_9 PF14580.1 CBZ26000.1 - 0.00067 19.2 4.8 0.12 11.8 1.4 2.5 1 1 2 3 3 3 3 Leucine-rich repeat DUF743 PF05332.6 CBZ26001.1 - 0.25 11.3 4.9 0.077 12.9 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF743) STAG PF08514.6 CBZ26003.1 - 4.3e-18 65.1 0.3 4.3e-18 65.1 0.2 2.5 2 0 0 2 2 2 1 STAG domain DUF2435 PF10363.4 CBZ26003.1 - 0.11 12.3 3.9 9.3 6.2 0.0 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF2435) Proteasome PF00227.21 CBZ26005.1 - 1e-55 187.9 0.1 1.3e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ26005.1 - 9.6e-14 50.3 0.0 3.2e-13 48.7 0.0 2.0 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-CCHC PF00098.18 CBZ26006.1 - 2.3e-42 140.9 34.9 1.7e-09 37.1 0.7 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 CBZ26006.1 - 1.8e-13 49.9 30.6 0.00073 19.1 0.8 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 CBZ26006.1 - 1.7e-12 46.8 27.8 0.013 15.2 1.0 5.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.1 CBZ26006.1 - 2e-08 33.5 17.3 0.0021 17.5 0.1 4.9 2 2 3 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.1 CBZ26006.1 - 5.7e-05 22.7 28.4 0.025 14.2 1.2 5.1 2 2 3 5 5 5 3 Zinc knuckle Dermcidin PF15291.1 CBZ26006.1 - 0.12 12.6 0.6 1.1 9.4 0.1 2.2 1 1 1 2 2 2 0 Dermcidin, antibiotic peptide TNFR_c6 PF00020.13 CBZ26006.1 - 0.37 10.8 32.9 3.5 7.7 1.3 5.0 2 2 3 5 5 5 0 TNFR/NGFR cysteine-rich region RMF PF04957.7 CBZ26006.1 - 1.9 8.2 7.7 30 4.3 0.1 3.3 2 2 1 3 3 3 0 Ribosome modulation factor zf-C2HC_2 PF13913.1 CBZ26006.1 - 5.5 6.7 23.3 5.9 6.6 0.1 5.5 5 0 0 5 5 5 0 zinc-finger of a C2HC-type DUF2387 PF09526.5 CBZ26006.1 - 6.3 6.7 19.7 2.6 8.0 1.6 3.8 1 1 3 4 4 4 0 Probable metal-binding protein (DUF2387) zf-CCHC PF00098.18 CBZ26007.1 - 4.4e-41 136.9 36.3 2.6e-09 36.5 1.3 5.5 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.1 CBZ26007.1 - 3.1e-12 45.9 30.7 0.0015 18.1 0.8 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.1 CBZ26007.1 - 2.6e-11 43.0 28.4 0.02 14.5 0.8 5.2 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_2 PF13696.1 CBZ26007.1 - 1.5e-06 27.5 18.6 0.013 15.0 0.3 5.1 2 2 3 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.1 CBZ26007.1 - 0.00026 20.5 29.4 0.05 13.2 1.2 5.3 2 2 3 5 5 5 3 Zinc knuckle RMF PF04957.7 CBZ26007.1 - 3.3 7.4 6.9 31 4.3 0.1 3.5 2 1 1 3 3 3 0 Ribosome modulation factor TNFR_c6 PF00020.13 CBZ26007.1 - 7.6 6.6 33.2 6.7 6.8 1.4 5.2 2 2 3 5 5 5 0 TNFR/NGFR cysteine-rich region Clathrin PF00637.15 CBZ26008.1 - 2.3e-164 539.5 37.9 3.4e-28 98.0 0.1 8.6 9 0 0 9 9 9 8 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CBZ26008.1 - 4.6e-21 74.4 0.1 3.9e-20 71.5 0.0 2.8 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 CBZ26008.1 - 5.4e-15 54.5 1.4 0.3 11.4 0.0 6.8 7 0 0 7 7 7 5 Clathrin propeller repeat Clathrin-link PF09268.5 CBZ26008.1 - 1.3e-07 30.5 0.0 4.5e-07 28.7 0.0 2.1 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_1 PF00515.23 CBZ26008.1 - 0.0068 15.9 0.2 7.2 6.4 0.1 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ26008.1 - 0.0084 15.8 4.0 20 5.2 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat Egg_lysin PF01303.12 CBZ26008.1 - 0.089 12.8 4.9 1.1 9.2 0.4 3.5 3 0 0 3 3 3 0 Egg lysin (Sperm-lysin) DUF1626 PF07788.6 CBZ26008.1 - 0.091 12.5 0.6 3.4 7.5 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1626) zf-CCHC PF00098.18 CBZ26009.1 - 3.4e-39 130.9 51.0 2.9e-07 30.0 0.9 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_2 PF13696.1 CBZ26009.1 - 2.9e-09 36.2 34.7 0.0013 18.2 2.1 5.8 4 1 2 6 6 6 4 Zinc knuckle zf-CCHC_3 PF13917.1 CBZ26009.1 - 4.8e-08 32.5 31.9 0.019 14.6 0.6 5.0 3 2 2 5 5 5 4 Zinc knuckle zf-CCHC_4 PF14392.1 CBZ26009.1 - 7.2e-08 31.9 37.1 0.097 12.3 0.4 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.1 CBZ26009.1 - 5.2e-05 22.6 36.1 0.0021 17.5 0.9 5.2 4 1 1 5 5 5 4 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 CBZ26010.1 - 4.2e-84 272.7 91.8 4.7e-09 35.7 2.0 10.2 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_3 PF13917.1 CBZ26010.1 - 3.8e-27 93.7 60.4 0.0039 16.8 0.2 10.1 3 3 7 10 10 10 10 Zinc knuckle zf-CCHC_2 PF13696.1 CBZ26010.1 - 1.4e-11 43.7 52.1 0.11 12.0 0.3 10.2 10 0 0 10 10 10 10 Zinc knuckle zf-CCHC_4 PF14392.1 CBZ26010.1 - 1.8e-11 43.5 72.6 0.34 10.5 0.5 10.1 10 0 0 10 10 10 10 Zinc knuckle eIF3g PF12353.3 CBZ26010.1 - 0.015 15.2 0.9 0.015 15.2 0.6 9.5 5 3 5 10 10 10 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_6 PF15288.1 CBZ26010.1 - 8.6 6.1 79.7 1.2 8.8 0.5 10.2 10 0 0 10 10 10 0 Zinc knuckle Proteasome PF00227.21 CBZ26011.1 - 1.4e-49 167.9 0.2 1.7e-49 167.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit S4 PF01479.20 CBZ26012.1 - 1.6e-07 30.6 0.0 9.5e-07 28.1 0.0 2.2 2 0 0 2 2 2 1 S4 domain PseudoU_synth_2 PF00849.17 CBZ26012.1 - 2.6e-06 27.3 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF2419 PF10343.4 CBZ26013.1 - 2.2e-15 56.7 0.0 2.9e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) Peptidase_M76 PF09768.4 CBZ26015.1 - 1e-53 181.3 0.1 3.2e-52 176.4 0.1 2.0 1 1 0 1 1 1 1 Peptidase M76 family HTH_30 PF13556.1 CBZ26015.1 - 0.0052 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GPI2 PF06432.6 CBZ26017.1 - 1.9e-77 260.3 14.5 2.3e-77 260.1 10.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Sprouty PF05210.8 CBZ26017.1 - 0.0033 17.4 0.1 0.0082 16.1 0.1 1.7 1 0 0 1 1 1 1 Sprouty protein (Spry) DUF1634 PF07843.6 CBZ26017.1 - 0.012 15.2 1.5 0.11 12.1 0.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1634) DUF3488 PF11992.3 CBZ26017.1 - 3.3 6.2 12.1 0.73 8.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Beach PF02138.13 CBZ26018.1 - 3.2e-100 335.0 0.0 4.6e-100 334.5 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CBZ26018.1 - 1.9e-22 79.1 0.0 3.7e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 CBZ26018.1 - 0.00053 19.7 1.2 1.4 8.8 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Sec34 PF04136.10 CBZ26019.1 - 2.1e-05 24.2 1.0 3.5e-05 23.5 0.2 1.7 2 0 0 2 2 2 1 Sec34-like family Syntaxin-6_N PF09177.6 CBZ26019.1 - 2.9 8.3 7.3 4.7 7.6 0.5 3.1 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DLH PF01738.13 CBZ26021.1 - 0.075 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Aldedh PF00171.17 CBZ26022.1 - 4e-162 539.7 0.2 4.5e-162 539.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3253 PF11625.3 CBZ26022.1 - 0.037 13.9 0.4 0.11 12.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) DUF1487 PF07368.6 CBZ26022.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) TPR_11 PF13414.1 CBZ26024.1 - 5.1e-33 112.5 8.0 1.3e-08 34.3 0.0 6.5 4 2 3 7 7 7 5 TPR repeat TPR_2 PF07719.12 CBZ26024.1 - 4e-20 70.0 10.3 0.00011 21.8 0.1 9.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ26024.1 - 1.5e-16 59.1 8.8 4.5e-05 22.8 0.0 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ26024.1 - 1e-10 41.2 17.5 8.6e-08 31.9 0.4 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ26024.1 - 1.4e-10 40.9 12.3 0.024 14.5 0.1 6.9 4 2 4 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ26024.1 - 7.2e-10 39.0 16.5 0.021 15.1 0.2 7.3 4 2 4 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ26024.1 - 4.2e-09 36.2 19.6 0.88 10.3 0.3 9.5 5 3 5 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ26024.1 - 5.5e-06 26.1 5.5 3.6 8.0 0.0 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ26024.1 - 1.6e-05 24.3 18.2 0.037 13.8 0.1 7.3 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ26024.1 - 4.1e-05 24.1 29.2 0.06 14.0 0.1 7.5 8 2 1 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ26024.1 - 0.00021 20.8 0.1 13 5.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ26024.1 - 0.00049 20.1 12.6 6.8 6.9 0.1 5.9 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CBZ26024.1 - 0.0012 17.9 1.4 0.43 9.6 0.0 4.2 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 CBZ26024.1 - 0.064 13.3 2.9 0.2 11.7 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.13 CBZ26024.1 - 0.069 13.0 0.8 3.8 7.4 0.0 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 CBZ26024.1 - 3.5 8.3 9.6 34 5.2 0.0 6.4 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ26024.1 - 4.8 7.9 7.8 9.6 6.9 0.1 4.5 4 0 0 4 4 3 0 Tetratricopeptide repeat XRN_N PF03159.13 CBZ26025.1 - 5.5e-84 281.2 0.0 5.5e-84 281.2 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus MORN PF02493.15 CBZ26027.1 - 6.3e-56 182.9 86.4 4.1e-07 29.3 0.4 18.7 20 0 0 20 20 20 15 MORN repeat SM-ATX PF14438.1 CBZ26027.1 - 0.85 9.5 3.5 1.7e+02 2.2 0.0 4.9 6 0 0 6 6 6 0 Ataxin 2 SM domain DUF3048 PF11258.3 CBZ26027.1 - 2.5 7.1 7.0 0.71 8.9 0.2 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3048) Ras PF00071.17 CBZ26028.1 - 3.7e-14 52.4 0.0 6e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ26028.1 - 5.6e-13 49.4 0.0 1.6e-12 47.9 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 CBZ26028.1 - 0.012 15.7 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CBZ26028.1 - 0.028 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 CBZ26028.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Arf PF00025.16 CBZ26028.1 - 0.21 10.8 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family DEAD PF00270.24 CBZ26030.1 - 3.7e-39 133.9 0.0 8.5e-39 132.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ26030.1 - 7.7e-20 70.5 0.0 1.6e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBZ26030.1 - 6.6e-17 60.8 0.0 1.3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.24 CBZ26031.1 - 3.7e-43 146.9 0.2 8.8e-43 145.7 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ26031.1 - 1.2e-24 85.9 0.1 6.7e-24 83.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ26031.1 - 0.0005 19.9 0.1 0.0021 17.9 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Ribosomal_S5_C PF03719.10 CBZ26032.1 - 2.7e-15 55.3 0.1 4.8e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 CBZ26032.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain MVP_shoulder PF11978.3 CBZ26033.1 - 1.1e-47 160.7 0.0 1.9e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.13 CBZ26033.1 - 7.4e-23 80.3 0.0 2.1e-08 34.0 0.0 4.7 4 0 0 4 4 4 3 Major Vault Protein repeat CBF PF03914.12 CBZ26034.1 - 1.2e-38 132.2 2.6 1.5e-38 131.8 0.0 2.3 3 0 0 3 3 3 1 CBF/Mak21 family NOC3p PF07540.6 CBZ26034.1 - 0.00036 20.7 0.0 0.00036 20.7 0.0 2.0 2 0 0 2 2 2 1 Nucleolar complex-associated protein DUF607 PF04678.8 CBZ26034.1 - 0.057 13.3 1.2 0.18 11.7 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF607 GAS PF13851.1 CBZ26038.1 - 7.5e-62 208.1 27.9 7.5e-62 208.1 19.3 3.8 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding DUF3086 PF11285.3 CBZ26038.1 - 0.0039 16.0 3.1 0.0039 16.0 2.2 2.9 2 1 0 3 3 3 1 Protein of unknown function (DUF3086) FAM74 PF15026.1 CBZ26038.1 - 0.075 12.6 0.0 0.075 12.6 0.0 2.4 2 1 0 2 2 2 0 FAM74 protein Filament PF00038.16 CBZ26038.1 - 0.95 8.8 65.1 0.51 9.7 4.6 4.2 1 1 2 3 3 3 0 Intermediate filament protein Flavodoxin_NdrI PF07972.6 CBZ26039.1 - 0.053 13.4 0.0 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 NrdI Flavodoxin like DUF607 PF04678.8 CBZ26039.1 - 0.14 12.0 0.1 0.14 12.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF607 Baculo_PEP_C PF04513.7 CBZ26039.1 - 0.19 11.5 1.1 5.9 6.7 0.0 3.3 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 CBZ26039.1 - 1.1 8.8 20.2 1.9 8.0 3.6 3.6 2 2 1 3 3 3 0 IncA protein TPR_MLP1_2 PF07926.7 CBZ26039.1 - 3.2 7.5 21.1 0.98 9.1 2.4 4.4 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein CorA PF01544.13 CBZ26039.1 - 4.9 6.1 11.4 0.23 10.4 1.2 3.1 3 1 1 4 4 4 0 CorA-like Mg2+ transporter protein Ribosomal_L37ae PF01780.14 CBZ26040.1 - 2e-36 123.7 5.1 2.1e-36 123.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.17 CBZ26040.1 - 0.00075 19.1 2.1 0.0011 18.6 1.4 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 CBZ26040.1 - 0.024 14.1 1.2 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain UPF0547 PF10571.4 CBZ26040.1 - 0.046 13.4 1.1 7.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 NOB1_Zn_bind PF08772.6 CBZ26040.1 - 0.089 12.6 3.7 0.98 9.2 2.6 2.3 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Carla_C4 PF01623.12 CBZ26040.1 - 0.094 12.4 1.6 0.12 12.1 1.1 1.3 1 1 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Zn_Tnp_IS1595 PF12760.2 CBZ26040.1 - 0.12 12.2 2.5 0.18 11.6 1.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C4_ClpX PF06689.8 CBZ26040.1 - 6.6 6.3 7.0 1.2 8.7 2.1 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-RING_2 PF13639.1 CBZ26041.1 - 6.2e-12 45.1 9.3 9.7e-12 44.5 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ26041.1 - 2.3e-11 43.5 7.6 3.6e-11 42.8 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ26041.1 - 1.1e-10 41.0 5.9 1.6e-10 40.4 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ26041.1 - 2e-09 36.9 3.8 3.1e-09 36.3 2.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ26041.1 - 8.7e-08 31.7 5.9 1.3e-07 31.2 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CBZ26041.1 - 8.8e-08 31.7 2.3 1.4e-07 31.1 0.5 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBZ26041.1 - 1.1e-07 31.5 6.7 1.9e-07 30.8 4.6 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 CBZ26041.1 - 0.0018 17.7 5.6 0.0041 16.6 3.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 CBZ26041.1 - 0.0028 17.4 2.1 0.0049 16.6 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBZ26041.1 - 0.0057 16.7 7.7 0.014 15.4 5.4 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger Baculo_IE-1 PF05290.6 CBZ26041.1 - 0.0074 16.0 1.9 0.012 15.3 1.3 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.1 CBZ26041.1 - 0.0089 15.7 3.8 0.018 14.8 2.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF1244 PF06844.6 CBZ26041.1 - 0.041 13.7 0.2 0.15 11.8 0.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1244) zf-Nse PF11789.3 CBZ26041.1 - 0.049 13.1 2.0 0.089 12.3 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 CBZ26041.1 - 0.061 12.9 5.0 0.15 11.6 3.5 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 CBZ26041.1 - 0.19 11.2 5.7 0.31 10.6 3.9 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger IBR PF01485.16 CBZ26041.1 - 2.5 8.0 8.6 1.6 8.6 4.6 1.7 1 1 0 1 1 1 0 IBR domain Nucleoside_tran PF01733.13 CBZ26042.1 - 1.9e-26 92.9 7.3 1.9e-26 92.9 5.1 2.2 2 1 0 2 2 2 1 Nucleoside transporter MutS_V PF00488.16 CBZ26043.1 - 1.8e-63 214.1 0.1 7.1e-63 212.1 0.0 2.0 1 1 0 1 1 1 1 MutS domain V MutS_I PF01624.15 CBZ26043.1 - 7.7e-34 116.1 0.1 1.8e-33 114.9 0.1 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.13 CBZ26043.1 - 1.6e-26 93.4 0.0 6.1e-26 91.4 0.0 2.1 1 1 0 1 1 1 1 MutS domain III ABC_tran PF00005.22 CBZ26043.1 - 0.0027 18.0 0.0 0.0078 16.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CBZ26043.1 - 0.0027 17.1 3.5 0.0096 15.4 0.0 2.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CBZ26043.1 - 0.04 13.3 0.0 0.088 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBZ26043.1 - 0.39 10.6 5.4 0.51 10.3 0.0 3.5 4 1 0 4 4 4 0 AAA ATPase domain TLD PF07534.11 CBZ26044.1 - 2.3e-22 79.4 0.1 2.9e-21 75.9 0.1 2.1 1 1 0 1 1 1 1 TLD PMM PF03332.8 CBZ26045.1 - 4.6e-101 336.9 0.8 5.2e-101 336.8 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CBZ26045.1 - 3e-08 33.5 0.0 6e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CBZ26045.1 - 6.3e-06 25.6 0.0 0.027 13.7 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.2 CBZ26045.1 - 0.1 12.7 0.4 0.42 10.7 0.3 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase 2OG-FeII_Oxy_2 PF13532.1 CBZ26046.1 - 2.9e-08 33.7 0.0 5e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBZ26046.1 - 2e-06 28.0 0.0 3.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.23 CBZ26047.1 - 5.2e-21 74.9 0.0 7.1e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3900 PF13039.1 CBZ26048.1 - 0.036 13.6 0.1 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3900) FUSC PF04632.7 CBZ26050.1 - 0.37 9.1 15.1 0.43 8.9 10.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family tRNA_U5-meth_tr PF05958.6 CBZ26050.1 - 0.48 9.0 7.0 0.71 8.5 4.8 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase V_ATPase_I PF01496.14 CBZ26050.1 - 0.73 7.6 8.9 0.96 7.2 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fez1 PF06818.10 CBZ26050.1 - 1.8 8.5 26.2 0.88 9.5 4.0 2.3 1 1 1 2 2 2 0 Fez1 CHD5 PF04420.9 CBZ26050.1 - 2.6 7.7 5.1 1.2 8.7 0.6 2.3 2 1 1 3 3 3 0 CHD5-like protein Cpn60_TCP1 PF00118.19 CBZ26051.1 - 6.1e-116 387.8 10.7 7.3e-116 387.6 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.19 CBZ26052.1 - 7.4e-117 390.9 10.1 8.8e-117 390.6 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.27 CBZ26053.1 - 9.7e-06 25.2 12.2 0.0005 19.8 0.8 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ALG3 PF05208.8 CBZ26054.1 - 4.2e-111 371.7 14.9 5.1e-111 371.4 10.3 1.0 1 0 0 1 1 1 1 ALG3 protein DUF3146 PF11344.3 CBZ26054.1 - 0.32 10.4 2.4 0.29 10.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3146) Metallophos PF00149.23 CBZ26055.1 - 3.2e-20 72.3 0.0 1.3e-16 60.6 0.0 2.9 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase DUF3827 PF12877.2 CBZ26055.1 - 5.3 5.0 5.8 13 3.7 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) DUF72 PF01904.13 CBZ26056.1 - 1.5e-33 116.4 0.0 1.2e-32 113.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF72 CAP_N PF01213.14 CBZ26056.1 - 4.8 6.3 6.2 1.2 8.3 1.3 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal TPR_11 PF13414.1 CBZ26057.1 - 3.1e-18 65.1 2.8 6.6e-10 38.5 0.0 2.7 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBZ26057.1 - 4.5e-12 44.9 9.3 4.9e-07 29.1 0.5 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ26057.1 - 3e-10 39.2 7.0 2.1e-05 23.9 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ26057.1 - 6.9e-09 36.1 15.1 2e-05 25.0 2.4 4.4 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ26057.1 - 6.6e-06 26.3 9.3 1.8e-05 24.9 2.7 3.7 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ26057.1 - 0.0002 21.2 3.0 0.0037 17.1 0.6 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ26057.1 - 0.00046 19.7 0.0 0.0077 15.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ26057.1 - 0.00066 19.2 0.9 0.013 15.2 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ26057.1 - 0.027 14.3 2.1 0.15 12.0 0.5 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ26057.1 - 0.089 13.1 3.4 0.26 11.6 1.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ26057.1 - 0.26 11.8 3.8 0.5 10.9 0.0 3.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ26057.1 - 0.8 9.5 6.3 10 6.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SPA PF08616.5 CBZ26059.1 - 0.00021 20.9 0.0 0.0006 19.4 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CBZ26059.1 - 0.0068 14.9 0.0 0.012 14.0 0.0 1.4 1 0 0 1 1 1 1 Transport protein Avl9 Acetyltransf_10 PF13673.1 CBZ26060.1 - 7.9e-05 22.7 0.0 0.0018 18.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBZ26060.1 - 0.0029 17.5 0.0 0.0069 16.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CBZ26060.1 - 0.018 14.8 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CBZ26060.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaJ PF00226.26 CBZ26061.1 - 3.9e-21 74.5 0.5 5.8e-21 74.0 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 CBZ26061.1 - 7.9e-06 26.0 1.0 0.00013 22.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DEAD PF00270.24 CBZ26064.1 - 2.7e-45 153.9 0.0 1.2e-44 151.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ26064.1 - 3e-25 87.8 0.0 7.6e-25 86.5 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ26064.1 - 0.0025 17.6 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CBZ26064.1 - 0.015 14.9 0.0 0.12 11.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain HAD_2 PF13419.1 CBZ26065.1 - 9.3e-08 32.4 0.4 0.00021 21.5 0.0 3.4 4 0 0 4 4 4 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBZ26065.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 HAD-hyrolase-like EMP24_GP25L PF01105.19 CBZ26066.1 - 2.9e-28 98.8 0.0 4.2e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GPI-anchored PF10342.4 CBZ26066.1 - 0.054 13.9 0.1 8.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Dynein_light PF01221.13 CBZ26067.1 - 5.2e-22 77.6 0.0 6.6e-22 77.3 0.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 DUF523 PF04463.7 CBZ26067.1 - 0.072 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF523) DUF3646 PF12362.3 CBZ26067.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Nol1_Nop2_Fmu PF01189.12 CBZ26068.1 - 1.5e-23 83.6 0.0 2.4e-16 59.9 0.0 3.0 2 1 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CBZ26068.1 - 0.00081 19.4 0.0 0.0044 17.0 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Y_phosphatase PF00102.22 CBZ26069.1 - 3.5e-44 150.8 0.0 9.4e-44 149.4 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBZ26069.1 - 5.4e-05 22.7 0.1 0.00016 21.2 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain FAM220 PF15487.1 CBZ26069.1 - 0.84 8.9 3.1 0.56 9.5 0.2 1.9 1 1 1 2 2 2 0 FAM220 family Choline_transpo PF04515.7 CBZ26072.1 - 1.4e-86 290.2 34.1 1.4e-86 290.2 23.6 2.8 1 1 0 2 2 2 1 Plasma-membrane choline transporter PTCB-BRCT PF12738.2 CBZ26073.1 - 0.0024 17.6 0.1 1.9 8.3 0.0 2.9 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.21 CBZ26073.1 - 0.0067 16.5 0.0 0.74 10.0 0.0 2.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Sec1 PF00995.18 CBZ26074.1 - 4.5e-118 395.3 0.0 5.1e-118 395.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Spc97_Spc98 PF04130.8 CBZ26075.1 - 1.6e-15 56.4 0.0 3e-12 45.6 0.0 3.0 3 0 0 3 3 3 2 Spc97 / Spc98 family TGS PF02824.16 CBZ26076.1 - 3.3e-19 68.4 0.0 6.2e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CBZ26076.1 - 4.9e-17 61.9 0.0 1.1e-16 60.8 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ26076.1 - 2.4e-09 36.6 0.0 8.9e-09 34.8 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 CBZ26076.1 - 0.0024 16.7 0.1 0.0072 15.1 0.0 1.7 2 0 0 2 2 2 1 ArgK protein GTP_EFTU PF00009.22 CBZ26076.1 - 0.006 16.0 0.3 5.2 6.4 0.0 3.3 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 CBZ26076.1 - 0.011 16.1 0.0 0.057 13.9 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 CBZ26076.1 - 0.014 15.1 0.2 0.74 9.6 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Guanylate_kin PF00625.16 CBZ26077.1 - 8.2e-41 139.4 0.0 5.9e-23 81.2 0.0 2.9 2 1 0 2 2 2 2 Guanylate kinase AAA_33 PF13671.1 CBZ26077.1 - 6.1e-07 29.4 0.3 0.00011 22.1 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ26077.1 - 1.4e-05 25.2 0.0 2.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 CBZ26077.1 - 0.00027 19.7 0.0 0.00038 19.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CBZ26077.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBZ26077.1 - 0.0023 17.1 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CBZ26077.1 - 0.0032 17.7 0.0 0.084 13.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBZ26077.1 - 0.004 17.9 0.0 0.0087 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBZ26077.1 - 0.0041 17.2 0.0 0.036 14.2 0.0 2.2 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 CBZ26077.1 - 0.0065 16.7 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CBZ26077.1 - 0.0088 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CBZ26077.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 CBZ26077.1 - 0.021 14.8 0.2 0.091 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CBZ26077.1 - 0.023 14.9 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CBZ26077.1 - 0.032 13.9 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 CBZ26077.1 - 0.037 13.7 0.0 0.095 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 CBZ26077.1 - 0.041 13.5 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 CBZ26077.1 - 0.047 12.8 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 CBZ26077.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TPR_11 PF13414.1 CBZ26079.1 - 2.1e-43 145.7 5.0 6.1e-12 45.0 0.1 6.1 4 2 2 6 6 6 6 TPR repeat TPR_1 PF00515.23 CBZ26079.1 - 1.2e-34 116.4 1.2 0.00031 20.2 0.0 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ26079.1 - 8.7e-32 106.4 6.6 0.0013 18.4 0.1 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ26079.1 - 1.8e-24 85.4 15.0 1.9e-05 24.5 0.5 6.8 4 3 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ26079.1 - 2e-24 85.6 4.9 1.4e-05 25.6 0.1 6.7 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ26079.1 - 6e-23 79.0 3.5 0.00017 21.5 0.0 8.3 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ26079.1 - 7.4e-19 66.0 0.0 0.016 14.9 0.0 7.7 8 1 1 9 9 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ26079.1 - 2.1e-18 65.1 10.1 9.4e-05 22.7 0.2 8.0 4 3 3 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ26079.1 - 2.4e-17 63.0 1.7 8.1e-08 32.4 0.1 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ26079.1 - 1.2e-15 57.4 15.0 2.5e-06 27.5 0.0 6.1 2 2 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBZ26079.1 - 4.2e-14 51.9 4.3 0.83 10.2 0.0 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ26079.1 - 3.8e-13 49.0 12.2 2.4e-05 24.1 0.1 5.4 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ26079.1 - 8.4e-10 37.7 8.5 0.14 11.9 0.1 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.1 CBZ26079.1 - 1.3e-05 25.2 0.1 0.79 9.8 0.0 4.4 4 1 1 5 5 4 2 Tetratricopeptide repeat Paf67 PF10255.4 CBZ26079.1 - 0.00015 20.8 0.3 0.35 9.6 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase I-associated factor PAF67 TPR_4 PF07721.9 CBZ26079.1 - 0.00047 20.3 10.6 0.037 14.4 0.7 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ26079.1 - 0.0011 18.7 1.1 0.023 14.6 0.1 7.1 9 0 0 9 9 7 2 Tetratricopeptide repeat ChAPs PF09295.5 CBZ26079.1 - 0.0018 17.1 1.1 0.41 9.3 0.0 2.9 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.3 CBZ26079.1 - 0.022 13.5 0.1 4.4 5.9 0.0 3.4 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 CBZ26079.1 - 0.026 13.5 6.6 2 7.4 0.0 4.2 2 2 1 4 4 4 0 Tetratricopeptide repeat GM_CSF PF01109.12 CBZ26079.1 - 0.036 14.0 0.0 1.8 8.5 0.1 2.5 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor DUF3808 PF10300.4 CBZ26079.1 - 0.036 12.6 0.1 0.054 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.1 CBZ26079.1 - 0.041 13.7 5.5 13 5.7 0.1 5.7 6 1 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CBZ26079.1 - 0.048 13.8 0.2 43 4.3 0.0 3.3 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation DUF3856 PF12968.2 CBZ26079.1 - 0.11 12.2 3.4 5.3 6.8 0.0 3.5 5 0 0 5 5 4 0 Domain of Unknown Function (DUF3856) SNAP PF14938.1 CBZ26079.1 - 0.12 11.4 0.6 0.88 8.6 0.2 2.6 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP BTAD PF03704.12 CBZ26079.1 - 0.23 11.7 10.6 0.057 13.7 1.8 3.3 3 2 1 4 4 4 0 Bacterial transcriptional activator domain Apc5 PF12862.2 CBZ26079.1 - 0.45 10.3 2.5 17 5.3 0.0 3.5 3 1 0 3 3 2 0 Anaphase-promoting complex subunit 5 Pkinase PF00069.20 CBZ26080.1 - 6.1e-52 176.3 0.0 1.7e-51 174.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26080.1 - 6.7e-35 120.4 0.0 5.2e-34 117.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ26080.1 - 5.4e-07 28.8 0.0 7.4e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBZ26080.1 - 0.044 12.6 0.1 0.067 12.0 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 CBZ26080.1 - 0.072 11.8 0.0 0.15 10.7 0.0 1.4 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ribosomal_S18 PF01084.15 CBZ26082.1 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 Glucokinase PF02685.11 CBZ26083.1 - 1.7e-15 56.6 0.0 6.3e-15 54.7 0.0 1.8 1 1 0 1 1 1 1 Glucokinase Endonuclease_5 PF04493.9 CBZ26084.1 - 3.5e-42 144.1 0.0 5e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease V DUF99 PF01949.11 CBZ26084.1 - 0.082 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 adh_short PF00106.20 CBZ26085.1 - 4.5e-13 49.4 4.8 6.7e-12 45.6 3.3 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBZ26085.1 - 1.6e-06 27.8 2.8 3.7e-06 26.7 1.9 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CBZ26085.1 - 0.0017 18.1 0.0 0.0055 16.4 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 CBZ26085.1 - 0.0059 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.16 CBZ26085.1 - 0.043 13.2 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 CBZ26085.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_C PF02800.15 CBZ26086.1 - 2.8e-71 238.0 0.0 3.8e-71 237.6 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBZ26086.1 - 6.4e-60 201.4 0.0 1.1e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CBZ26086.1 - 0.00078 19.3 0.7 0.0049 16.7 0.5 2.3 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 CBZ26086.1 - 0.09 11.9 0.1 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_1_2 PF00155.16 CBZ26087.1 - 2.7e-60 204.2 0.0 3.3e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CBZ26087.1 - 0.0016 16.7 0.0 0.0026 16.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme COX4 PF02936.9 CBZ26087.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Sterol_MT_C PF08498.5 CBZ26089.1 - 1.3e-25 89.1 0.0 2.2e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 CBZ26089.1 - 1.3e-16 60.8 0.2 1.2e-15 57.7 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ26089.1 - 2e-12 46.9 0.1 4.6e-12 45.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CBZ26089.1 - 2.6e-09 36.5 0.0 4.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CBZ26089.1 - 2.6e-08 33.7 0.0 6.4e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ26089.1 - 1.4e-07 30.9 0.0 2.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CBZ26089.1 - 2e-07 31.3 0.7 2.4e-06 27.9 0.0 2.8 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ26089.1 - 2e-06 28.0 0.2 5.8e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ26089.1 - 1.2e-05 25.8 0.0 0.00017 22.1 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ26089.1 - 0.00046 20.2 0.0 0.0035 17.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 CBZ26089.1 - 0.0032 17.0 0.3 0.005 16.4 0.2 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 CBZ26089.1 - 0.072 12.4 0.1 0.36 10.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Sterol_MT_C PF08498.5 CBZ26090.1 - 1.3e-25 89.1 0.0 2.2e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 CBZ26090.1 - 1.3e-16 60.8 0.2 1.2e-15 57.7 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ26090.1 - 1.2e-12 47.6 0.1 2.9e-12 46.4 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CBZ26090.1 - 2.3e-09 36.7 0.0 3.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 CBZ26090.1 - 2.5e-08 33.8 0.0 6.1e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ26090.1 - 1.4e-07 30.8 0.0 2.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CBZ26090.1 - 1.9e-07 31.4 0.6 2.4e-06 27.9 0.0 2.8 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ26090.1 - 4e-06 27.1 0.1 1.2e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ26090.1 - 1.2e-05 25.9 0.0 0.00016 22.1 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ26090.1 - 0.00049 20.1 0.0 0.0037 17.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 CBZ26090.1 - 0.0019 17.7 0.3 0.003 17.1 0.2 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 CBZ26090.1 - 0.12 11.7 0.1 0.61 9.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain EF-hand_7 PF13499.1 CBZ26091.1 - 0.0024 17.9 0.0 0.0078 16.3 0.0 1.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ26091.1 - 0.0089 15.2 0.0 6.5 6.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CBZ26091.1 - 0.035 13.9 0.0 7.5 6.7 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain Cullin_Nedd8 PF10557.4 CBZ26092.1 - 1e-20 73.3 0.4 2.3e-20 72.1 0.3 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Peptidase_S9 PF00326.16 CBZ26093.1 - 2.9e-31 108.3 0.0 5.6e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 CBZ26093.1 - 1.4e-23 83.0 0.0 2.4e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_5 PF12695.2 CBZ26093.1 - 0.00024 20.8 0.0 0.00083 19.1 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CBZ26093.1 - 0.051 13.0 0.0 0.31 10.4 0.0 1.9 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) EF-hand_6 PF13405.1 CBZ26094.1 - 0.00014 21.4 0.0 0.031 14.1 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 CBZ26094.1 - 0.00082 19.4 0.0 0.32 11.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ26094.1 - 0.0013 17.9 0.0 0.0047 16.1 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 CBZ26094.1 - 0.016 14.7 0.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair DUF3228 PF11539.3 CBZ26094.1 - 0.051 12.6 0.2 0.079 12.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) EF-hand_5 PF13202.1 CBZ26094.1 - 0.076 12.3 0.0 0.21 10.9 0.0 1.8 1 0 0 1 1 1 0 EF hand FYVE PF01363.16 CBZ26095.1 - 4.3e-09 36.1 9.3 7.6e-09 35.3 6.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 CBZ26095.1 - 0.0052 16.6 4.4 0.012 15.5 3.1 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger zf-B_box PF00643.19 CBZ26095.1 - 1.2 9.1 9.5 1.9 8.4 3.7 2.4 2 0 0 2 2 2 0 B-box zinc finger zf-CCHC_6 PF15288.1 CBZ26095.1 - 1.6 8.4 6.1 0.2 11.3 1.0 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-RING_5 PF14634.1 CBZ26095.1 - 4.1 7.2 9.6 11 5.8 6.7 1.8 1 1 0 1 1 1 0 zinc-RING finger domain C1_1 PF00130.17 CBZ26095.1 - 5.9 6.6 11.1 1.3 8.7 4.2 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) His_Phos_2 PF00328.17 CBZ26098.1 - 7.4e-18 64.9 0.0 2.1e-12 47.0 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.17 CBZ26099.1 - 0.071 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP_N PF01213.14 CBZ26099.1 - 2.5 7.3 8.1 0.24 10.6 2.6 1.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal WD40 PF00400.27 CBZ26101.1 - 4.1e-25 86.6 19.3 1.8e-06 27.5 0.4 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nic96 PF04097.9 CBZ26102.1 - 1.4e-100 337.1 0.2 1.9e-100 336.8 0.1 1.1 1 0 0 1 1 1 1 Nup93/Nic96 SNAPc_SNAP43 PF09808.4 CBZ26103.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DEAD PF00270.24 CBZ26104.1 - 2.1e-25 89.1 0.0 7e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ26104.1 - 1.4e-17 63.3 0.0 3.6e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CBZ26104.1 - 0.00048 20.1 0.0 0.0065 16.4 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain NAD_binding_3 PF03447.11 CBZ26104.1 - 0.077 13.3 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain FA_hydroxylase PF04116.8 CBZ26105.1 - 3.1e-14 53.3 12.7 3.1e-14 53.3 8.8 3.1 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily HEAT_2 PF13646.1 CBZ26107.1 - 0.0018 18.5 0.7 1 9.6 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CBZ26107.1 - 0.029 14.4 7.8 1.3 9.2 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat SipA PF09052.5 CBZ26107.1 - 0.75 8.1 2.8 1.3 7.3 2.0 1.3 1 0 0 1 1 1 0 Salmonella invasion protein A HEAT_EZ PF13513.1 CBZ26107.1 - 4.1 8.0 11.0 9.6 6.8 0.1 4.8 4 0 0 4 4 4 0 HEAT-like repeat His_Phos_2 PF00328.17 CBZ26108.1 - 1.7e-24 86.8 0.1 6.2e-24 84.9 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GDPD PF03009.12 CBZ26109.1 - 2.4e-36 125.5 0.0 3.8e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family His_Phos_2 PF00328.17 CBZ26110.1 - 1.8e-19 70.2 0.0 1.4e-18 67.3 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RCC1 PF00415.13 CBZ26111.1 - 3e-22 78.5 11.2 3.4e-06 27.1 0.0 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ26111.1 - 5.8e-17 60.8 16.6 1.8e-06 27.3 0.1 4.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.1 CBZ26111.1 - 0.024 14.7 0.1 5.4 7.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4213) Mur_ligase_M PF08245.7 CBZ26112.1 - 1.2e-10 41.7 0.1 4e-10 40.0 0.1 1.8 1 1 0 1 1 1 1 Mur ligase middle domain VRR_NUC PF08774.6 CBZ26113.1 - 1.1e-16 60.6 0.0 2.6e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Pkinase PF00069.20 CBZ26114.1 - 7.4e-26 90.8 0.0 1.3e-09 37.5 0.0 3.6 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26114.1 - 1.5e-09 37.3 0.0 2.6e-08 33.2 0.0 2.7 4 0 0 4 4 4 1 Protein tyrosine kinase PCI PF01399.22 CBZ26115.1 - 0.00037 20.7 0.0 0.42 10.9 0.0 3.0 3 1 0 3 3 3 2 PCI domain Methyltransf_11 PF08241.7 CBZ26116.1 - 3.4e-11 43.4 0.0 1.1e-07 32.1 0.0 3.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ26116.1 - 4.1e-08 33.4 0.0 2e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ26116.1 - 3.4e-07 30.1 0.0 5.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ26116.1 - 4.8e-07 30.3 0.0 0.0016 19.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ26116.1 - 4.9e-05 23.3 0.1 9.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ26116.1 - 0.00046 20.6 0.0 0.014 15.8 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ26116.1 - 0.0047 16.5 0.0 5.6 6.5 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain 2-oxoacid_dh PF00198.18 CBZ26117.1 - 1.3e-77 260.2 0.0 1.8e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 CBZ26117.1 - 1.6e-11 43.6 0.6 5.6e-11 41.8 0.4 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.17 CBZ26117.1 - 5.4e-11 41.9 0.0 1.6e-10 40.4 0.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme DUF3597 PF12200.3 CBZ26117.1 - 3.8 7.9 12.2 13 6.2 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Metallophos_2 PF12850.2 CBZ26118.1 - 1.3e-06 28.2 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pentapeptide PF00805.17 CBZ26120.1 - 2.9e-12 45.5 9.3 0.00024 20.2 0.6 4.5 2 1 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 CBZ26120.1 - 2e-11 43.5 6.7 1.7e-09 37.3 5.0 2.8 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 CBZ26120.1 - 3.5e-11 42.8 10.2 5.2e-06 26.2 0.7 3.9 2 1 3 5 5 5 4 Pentapeptide repeats (9 copies) DUF2894 PF11445.3 CBZ26121.1 - 0.047 13.9 11.9 0.92 9.7 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Acyl-CoA_dh_C PF12806.2 CBZ26121.1 - 0.69 9.7 11.1 0.25 11.1 5.6 1.8 2 1 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Peptidase_M41 PF01434.13 CBZ26123.1 - 7e-64 215.2 0.4 9.8e-64 214.7 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBZ26123.1 - 1.9e-41 141.3 0.0 3.6e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBZ26123.1 - 4.2e-06 26.2 0.8 0.00077 18.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 CBZ26123.1 - 1.3e-05 24.9 0.0 4.3e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ26123.1 - 2.9e-05 24.2 0.2 0.00072 19.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ26123.1 - 4.8e-05 23.2 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CBZ26123.1 - 5.1e-05 23.3 0.1 0.0057 16.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CBZ26123.1 - 0.00012 22.8 0.0 0.00035 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ26123.1 - 0.00013 21.1 0.0 0.0003 19.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CBZ26123.1 - 0.00078 19.1 0.1 0.011 15.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 CBZ26123.1 - 0.00078 19.1 0.1 0.0026 17.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CBZ26123.1 - 0.00087 18.7 0.0 0.0023 17.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CBZ26123.1 - 0.00098 17.9 0.0 0.0023 16.7 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_28 PF13521.1 CBZ26123.1 - 0.0012 18.8 0.0 0.006 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ26123.1 - 0.0026 18.0 0.0 0.0072 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CBZ26123.1 - 0.0046 16.1 0.2 0.01 15.0 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CBZ26123.1 - 0.0047 16.0 0.0 0.0093 15.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Rad17 PF03215.10 CBZ26123.1 - 0.01 14.5 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 CBZ26123.1 - 0.011 15.8 0.0 0.098 12.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 CBZ26123.1 - 0.014 15.2 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 CBZ26123.1 - 0.016 15.0 0.0 0.062 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Reprolysin_4 PF13583.1 CBZ26123.1 - 0.026 14.0 0.0 0.058 12.9 0.0 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ABC_tran PF00005.22 CBZ26123.1 - 0.061 13.6 0.6 0.27 11.5 0.2 2.2 2 0 0 2 2 2 0 ABC transporter KaiC PF06745.8 CBZ26123.1 - 0.076 12.1 0.1 0.66 9.0 0.0 2.4 3 0 0 3 3 3 0 KaiC Arch_ATPase PF01637.13 CBZ26123.1 - 0.079 12.6 0.0 0.23 11.1 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase Parvo_NS1 PF01057.12 CBZ26123.1 - 0.2 10.5 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 HEAT_EZ PF13513.1 CBZ26124.1 - 2.4e-05 24.6 3.6 0.027 14.9 0.0 5.5 6 0 0 6 6 6 1 HEAT-like repeat B56 PF01603.15 CBZ26124.1 - 0.0069 15.0 0.1 0.03 12.9 0.0 2.1 4 0 0 4 4 4 1 Protein phosphatase 2A regulatory B subunit (B56 family) Alph_Pro_TM PF09608.5 CBZ26124.1 - 0.024 14.1 0.0 0.063 12.7 0.0 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) HEAT PF02985.17 CBZ26124.1 - 0.046 13.8 2.3 16 5.9 0.0 5.5 6 0 0 6 6 6 0 HEAT repeat IBN_N PF03810.14 CBZ26124.1 - 0.071 13.0 2.2 0.49 10.3 0.1 3.3 3 1 0 3 3 3 0 Importin-beta N-terminal domain Tyr_Deacylase PF02580.11 CBZ26125.1 - 3.2e-41 140.7 0.0 3.5e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase MFS_1 PF07690.11 CBZ26127.1 - 5.8e-14 51.5 40.8 2.5e-13 49.4 18.9 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CBZ26127.1 - 1.3e-11 44.3 11.8 1.3e-11 44.3 8.2 2.0 2 1 0 2 2 2 1 Nodulin-like FixQ PF05545.6 CBZ26127.1 - 4.7 6.9 7.0 12 5.5 0.6 3.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ SPC12 PF06645.8 CBZ26127.1 - 8.4 6.2 9.0 1.4 8.7 0.4 3.5 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2399 PF09664.5 CBZ26129.1 - 0.0021 17.9 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) TP6A_N PF04406.9 CBZ26129.1 - 0.0039 16.8 0.0 0.096 12.3 0.0 2.4 2 0 0 2 2 2 1 Type IIB DNA topoisomerase NDK PF00334.14 CBZ26130.1 - 0.0011 18.7 0.0 0.033 13.9 0.0 3.1 3 0 0 3 3 3 1 Nucleoside diphosphate kinase Sigma70_r1_1 PF03979.9 CBZ26130.1 - 0.2 11.6 0.0 0.67 9.9 0.0 1.9 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 OB_NTP_bind PF07717.11 CBZ26134.1 - 2.6e-24 85.2 0.0 2.8e-23 81.9 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBZ26134.1 - 7.5e-20 70.8 0.0 2.4e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBZ26134.1 - 9.8e-13 47.7 0.0 3.6e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ26134.1 - 6.1e-08 32.3 0.2 3e-07 30.0 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ26134.1 - 2e-06 27.9 0.7 1.1e-05 25.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ26134.1 - 0.0027 17.4 0.1 0.0096 15.6 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 CBZ26134.1 - 0.053 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zot PF05707.7 CBZ26134.1 - 0.057 12.8 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ABC_tran PF00005.22 CBZ26134.1 - 0.069 13.4 0.1 0.83 9.9 0.1 2.7 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 CBZ26134.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.3 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.1 CBZ26134.1 - 0.54 10.1 0.0 0.54 10.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain Phytochelatin PF05023.9 CBZ26135.1 - 0.051 12.5 0.0 3.5 6.5 0.0 3.5 4 0 0 4 4 4 0 Phytochelatin synthase Vps5 PF09325.5 CBZ26136.1 - 0.0013 18.0 1.9 0.0017 17.6 0.9 1.3 1 1 0 1 1 1 1 Vps5 C terminal like RasGAP_C PF03836.10 CBZ26136.1 - 0.011 15.4 0.4 0.011 15.3 0.3 1.2 1 0 0 1 1 1 0 RasGAP C-terminus DUF2968 PF11180.3 CBZ26136.1 - 0.013 14.8 3.7 0.014 14.8 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spc7 PF08317.6 CBZ26136.1 - 0.024 13.2 1.6 0.024 13.2 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 CBZ26136.1 - 0.032 13.4 1.4 0.035 13.2 1.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 CBZ26136.1 - 0.04 13.5 4.6 0.061 12.9 3.2 1.3 1 1 0 1 1 1 0 IncA protein DUF3294 PF07957.6 CBZ26136.1 - 0.044 13.3 2.0 0.09 12.2 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3294) FUSC PF04632.7 CBZ26136.1 - 0.044 12.2 3.6 0.048 12.0 2.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family OmpH PF03938.9 CBZ26136.1 - 0.044 13.7 3.4 0.045 13.6 2.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.7 CBZ26136.1 - 0.047 13.5 3.6 0.076 12.8 2.5 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc24 PF08286.6 CBZ26136.1 - 0.05 13.3 1.8 0.06 13.0 1.3 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Borrelia_lipo_1 PF05714.6 CBZ26136.1 - 0.053 12.6 0.2 0.062 12.4 0.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein CENP-F_leu_zip PF10473.4 CBZ26136.1 - 0.054 13.3 3.5 0.079 12.8 2.4 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 CBZ26136.1 - 0.089 12.6 0.8 0.15 11.9 0.4 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Herpes_BLRF2 PF05812.7 CBZ26136.1 - 0.1 12.4 1.3 1.2 8.9 0.9 2.1 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Wbp11 PF09429.5 CBZ26136.1 - 0.11 12.5 2.4 0.13 12.2 1.1 1.6 1 1 1 2 2 2 0 WW domain binding protein 11 Mu-like_Pro PF10123.4 CBZ26136.1 - 0.11 11.9 1.6 0.17 11.2 1.1 1.4 1 1 0 1 1 1 0 Mu-like prophage I protein DUF972 PF06156.8 CBZ26136.1 - 0.12 12.7 1.8 0.17 12.2 1.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Bacillus_HBL PF05791.6 CBZ26136.1 - 0.12 11.7 0.9 0.13 11.5 0.6 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF2894 PF11445.3 CBZ26136.1 - 0.15 12.3 2.8 0.18 12.0 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF904 PF06005.7 CBZ26136.1 - 0.16 12.2 3.0 1.4 9.2 2.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) LCD1 PF09798.4 CBZ26136.1 - 0.17 9.8 1.6 0.19 9.6 1.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4407 PF14362.1 CBZ26136.1 - 0.18 10.7 2.2 0.18 10.7 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Reo_sigmaC PF04582.7 CBZ26136.1 - 0.19 10.8 1.5 0.24 10.5 1.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein bZIP_Maf PF03131.12 CBZ26136.1 - 0.32 11.2 3.8 0.87 9.9 2.7 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor DivIC PF04977.10 CBZ26136.1 - 0.44 10.0 7.2 2.1 7.8 0.6 2.1 1 1 1 2 2 2 0 Septum formation initiator T2SM PF04612.7 CBZ26136.1 - 0.75 9.5 4.1 0.35 10.6 0.7 1.7 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M NPV_P10 PF05531.7 CBZ26136.1 - 0.99 9.7 4.0 2.9 8.2 2.5 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein bZIP_2 PF07716.10 CBZ26136.1 - 1.4 8.7 6.4 9.8 6.0 0.9 2.1 2 0 0 2 2 2 0 Basic region leucine zipper DASH_Dad2 PF08654.5 CBZ26136.1 - 1.7 8.7 4.6 0.95 9.4 1.7 1.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 DUF4404 PF14357.1 CBZ26136.1 - 2.6 8.5 5.5 4.2 7.8 3.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) M PF02370.11 CBZ26136.1 - 3.9 8.1 6.3 16 6.2 0.1 2.7 2 0 0 2 2 2 0 M protein repeat Chlorosome_CsmC PF11098.3 CBZ26137.1 - 0.12 12.1 0.2 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C Ribosomal_S24e PF01282.14 CBZ26138.1 - 2.6e-27 94.4 0.0 4.6e-27 93.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Ribosomal_S24e PF01282.14 CBZ26139.1 - 2.6e-27 94.4 0.0 4.6e-27 93.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Motile_Sperm PF00635.21 CBZ26140.1 - 1e-12 47.6 0.0 0.023 14.3 0.0 6.3 5 0 0 5 5 5 4 MSP (Major sperm protein) domain ABC2_membrane PF01061.19 CBZ26141.1 - 9.1e-37 126.2 19.5 1.6e-36 125.4 13.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CBZ26141.1 - 6.5e-22 78.2 0.0 1.1e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ26141.1 - 9.8e-08 32.2 0.1 0.0018 18.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ26141.1 - 0.0001 22.3 4.5 0.001 19.0 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CBZ26141.1 - 0.00021 20.7 0.0 0.0023 17.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CBZ26141.1 - 0.00072 19.7 0.0 0.0048 17.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBZ26141.1 - 0.0047 16.5 2.0 0.3 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CBZ26141.1 - 0.005 16.0 0.1 0.009 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 CBZ26141.1 - 0.013 15.2 0.2 0.081 12.6 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 CBZ26141.1 - 0.023 14.6 0.1 0.061 13.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBZ26141.1 - 0.024 14.0 0.1 0.058 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBZ26141.1 - 0.029 15.1 0.0 0.06 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBZ26141.1 - 0.03 13.7 0.3 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.7 CBZ26141.1 - 0.053 13.1 0.4 0.3 10.7 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 CBZ26141.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 CBZ26141.1 - 0.17 11.1 0.0 1.4 8.0 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Pox_A9 PF04835.7 CBZ26141.1 - 0.23 11.3 2.9 20 5.1 0.2 3.2 3 0 0 3 3 3 0 A9 protein conserved region AAA_23 PF13476.1 CBZ26141.1 - 0.33 11.2 0.0 0.55 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBZ26141.1 - 0.6 9.9 3.1 0.55 10.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain MCM PF00493.18 CBZ26142.1 - 0.00037 19.4 0.0 0.00056 18.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family AAA_16 PF13191.1 CBZ26142.1 - 0.0058 16.6 1.6 0.012 15.5 0.2 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ26142.1 - 0.11 12.6 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain PHF5 PF03660.9 CBZ26144.1 - 4.6e-35 119.9 9.4 5.2e-35 119.7 6.5 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 CBZ26144.1 - 0.036 13.9 5.1 0.036 13.9 3.6 2.0 1 1 2 3 3 3 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 CBZ26144.1 - 0.42 9.9 9.4 0.76 9.1 0.4 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding zf-C3HC4_2 PF13923.1 CBZ26144.1 - 0.45 10.5 7.4 3.3 7.8 4.3 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 CBZ26144.1 - 2.3 8.1 9.4 0.79 9.6 4.6 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger Spt4 PF06093.8 CBZ26144.1 - 3.9 7.4 7.4 4.3 7.2 0.8 2.5 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger zf-C3HC4_3 PF13920.1 CBZ26144.1 - 8.6 6.1 14.3 21 4.8 7.7 2.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ26145.1 - 3.2e-13 49.2 6.6 3.2e-13 49.2 4.6 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CBZ26145.1 - 3.3e-08 33.5 2.7 8e-08 32.2 1.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBZ26145.1 - 5.9e-08 32.5 6.5 5.9e-08 32.5 4.5 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ26145.1 - 1.9e-07 30.6 4.4 1.9e-07 30.6 3.0 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ26145.1 - 5.6e-07 29.1 3.8 5.6e-07 29.1 2.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ26145.1 - 1.7e-06 27.6 4.8 1.7e-06 27.6 3.3 1.8 2 0 0 2 2 1 1 zinc-RING finger domain PHD PF00628.24 CBZ26145.1 - 0.009 15.6 8.7 0.015 14.9 3.6 2.4 2 0 0 2 2 2 1 PHD-finger zf-Apc11 PF12861.2 CBZ26145.1 - 0.062 13.1 4.6 0.19 11.5 3.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 CBZ26145.1 - 0.24 11.1 2.9 0.61 9.8 2.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 CBZ26145.1 - 0.25 10.9 5.1 0.7 9.5 3.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CBZ26145.1 - 0.32 11.0 5.2 1.2 9.0 3.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 CBZ26145.1 - 0.79 9.4 8.2 3.8 7.3 5.7 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 PI3_PI4_kinase PF00454.22 CBZ26146.1 - 9.3e-24 84.1 0.0 2.8e-23 82.6 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.7 CBZ26146.1 - 1e-06 27.9 0.0 2.7e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 NUC194 domain FATC PF02260.15 CBZ26146.1 - 0.00075 18.8 0.0 0.003 16.9 0.0 2.1 2 0 0 2 2 2 1 FATC domain BpuJI_N PF11564.3 CBZ26146.1 - 4 6.3 0.0 6.7 5.5 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal ATP-grasp_2 PF08442.5 CBZ26147.1 - 2.9e-65 219.4 3.8 4.2e-65 218.9 2.6 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CBZ26147.1 - 2.6e-21 75.7 1.1 2.6e-21 75.7 0.8 2.5 3 0 0 3 3 3 1 CoA-ligase SID-1_RNA_chan PF13965.1 CBZ26148.1 - 0.038 12.1 1.2 0.035 12.2 0.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 5TM-5TMR_LYT PF07694.7 CBZ26148.1 - 0.13 11.5 2.1 1.4 8.2 2.4 1.8 1 1 1 2 2 2 0 5TMR of 5TMR-LYT Bax1-I PF01027.15 CBZ26149.1 - 0.028 14.0 0.6 0.032 13.8 0.4 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 YlaH PF14036.1 CBZ26149.1 - 0.17 12.0 2.8 0.18 11.8 0.6 1.9 2 0 0 2 2 2 0 YlaH-like protein Bromodomain PF00439.20 CBZ26150.1 - 5.6e-23 80.6 0.0 9e-23 80.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain GTP1_OBG PF01018.17 CBZ26151.1 - 4.2e-35 120.7 5.0 6e-35 120.1 3.5 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.18 CBZ26151.1 - 9.2e-17 61.0 0.0 1.4e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ26151.1 - 2.4e-06 26.9 0.0 0.00012 21.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B rRNA_proc-arch PF13234.1 CBZ26152.1 - 7.7e-53 179.3 0.5 2.5e-52 177.6 0.2 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 CBZ26152.1 - 1.3e-52 177.6 0.3 3.7e-52 176.1 0.2 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CBZ26152.1 - 8e-25 87.2 0.5 3.7e-24 85.1 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ26152.1 - 8.1e-07 28.8 0.0 2.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ26152.1 - 0.00047 20.0 0.0 0.0025 17.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBZ26152.1 - 0.0012 18.5 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 CBZ26152.1 - 0.0032 16.7 0.0 0.0071 15.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Zot PF05707.7 CBZ26152.1 - 0.0038 16.7 0.0 0.014 14.8 0.0 1.9 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) Arch_ATPase PF01637.13 CBZ26152.1 - 0.012 15.3 0.9 0.034 13.8 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 CBZ26152.1 - 0.031 13.1 0.0 0.077 11.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein CobA_CobO_BtuR PF02572.10 CBZ26152.1 - 0.059 12.9 0.2 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP RMMBL PF07521.7 CBZ26152.1 - 0.08 12.7 0.0 2.5 7.9 0.0 2.8 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase FlxA PF14282.1 CBZ26152.1 - 0.11 12.3 5.6 0.23 11.4 3.9 1.4 1 0 0 1 1 1 0 FlxA-like protein GSHPx PF00255.14 CBZ26153.1 - 1.4e-27 95.1 0.1 1.8e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CBZ26153.1 - 0.00074 19.2 0.0 0.00092 18.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBZ26153.1 - 0.0021 17.5 0.1 0.003 17.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin RNase_PH PF01138.16 CBZ26154.1 - 3.9e-30 104.8 0.3 5.6e-30 104.3 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBZ26154.1 - 3.1e-05 23.8 0.0 6.4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1623 PF07785.6 CBZ26154.1 - 0.039 13.8 0.6 0.072 13.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) Adap_comp_sub PF00928.16 CBZ26155.1 - 7.2e-55 185.9 0.0 9.1e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBZ26155.1 - 6.9e-05 22.5 0.3 0.00011 21.9 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RRM_1 PF00076.17 CBZ26156.1 - 5.4e-09 35.5 0.0 7.7e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ26156.1 - 2.3e-07 30.5 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ26156.1 - 0.00073 19.4 0.0 0.00097 19.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBZ26156.1 - 0.0067 16.2 0.1 0.0089 15.8 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif Phage_Gp23 PF10669.4 CBZ26156.1 - 0.031 14.3 1.5 0.044 13.8 1.1 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Cullin PF00888.17 CBZ26158.1 - 2.2e-48 165.2 0.6 2.8e-48 164.8 0.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBZ26158.1 - 1e-14 54.0 0.0 3.3e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain Fibrillarin PF01269.12 CBZ26159.1 - 1.2e-103 344.9 0.0 1.3e-103 344.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CBZ26159.1 - 0.0035 16.8 0.0 0.0053 16.2 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CBZ26159.1 - 0.039 13.4 0.1 0.061 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BPL_LplA_LipB PF03099.14 CBZ26160.1 - 2.6e-06 27.4 0.0 6e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Thioredoxin PF00085.15 CBZ26161.1 - 0.076 12.6 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin vATP-synt_E PF01991.13 CBZ26162.1 - 1.2e-40 138.9 7.6 1.4e-40 138.7 5.3 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF1778 PF08681.6 CBZ26162.1 - 0.037 13.8 5.6 0.11 12.2 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1778) Cons_hypoth95 PF03602.10 CBZ26162.1 - 0.051 12.9 1.3 0.081 12.3 0.8 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein 95 DUF932 PF06067.6 CBZ26162.1 - 1.8 7.8 9.6 1.6 7.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF932) EF-hand_8 PF13833.1 CBZ26164.1 - 1.2e-06 27.9 0.1 4.2e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.1 CBZ26164.1 - 0.0005 20.1 0.4 0.013 15.6 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ26164.1 - 0.023 13.9 0.3 9.8 5.7 0.0 3.6 4 0 0 4 4 4 0 EF hand Pro_isomerase PF00160.16 CBZ26165.1 - 1.6e-34 119.3 0.0 1.8e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArfGap PF01412.13 CBZ26167.1 - 1.5e-25 89.2 0.0 2.3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TBCC PF07986.7 CBZ26168.1 - 2.5e-26 91.4 0.8 4.8e-26 90.5 0.6 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CDC37_N PF03234.9 CBZ26168.1 - 0.25 11.6 3.9 0.4 10.9 2.7 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding cobW PF02492.14 CBZ26169.1 - 9.8e-46 155.4 0.1 1.5e-45 154.8 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 CBZ26169.1 - 0.00064 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 CBZ26169.1 - 0.0021 17.7 0.2 0.0093 15.7 0.1 2.2 2 1 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 CBZ26169.1 - 0.01 16.1 0.5 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBZ26169.1 - 0.027 14.0 0.1 0.085 12.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CBZ26169.1 - 0.031 14.4 0.1 0.079 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBZ26169.1 - 0.051 13.4 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CBZ26169.1 - 0.072 13.0 0.2 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 CBZ26169.1 - 0.11 12.2 0.2 0.28 10.8 0.1 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CBZ26169.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Guanylate_cyc PF00211.15 CBZ26170.1 - 9.9e-36 122.8 0.0 1.8e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1935 PF09149.5 CBZ26170.1 - 1.5e-28 98.7 0.0 3.6e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peripla_BP_6 PF13458.1 CBZ26170.1 - 4.6e-06 26.2 4.8 0.016 14.5 0.8 2.4 2 0 0 2 2 2 2 Periplasmic binding protein DUF2668 PF10873.3 CBZ26170.1 - 0.015 15.4 0.2 0.041 14.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) EphA2_TM PF14575.1 CBZ26170.1 - 2.2 8.7 4.5 0.33 11.3 0.1 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain zf-CCHC PF00098.18 CBZ26171.1 - 4.2e-21 73.8 79.1 0.00034 20.3 0.7 10.2 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.1 CBZ26171.1 - 0.00018 20.9 0.8 0.00018 20.9 0.5 7.5 4 2 3 7 7 7 4 Zinc knuckle NYN PF01936.13 CBZ26171.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.7 1 1 0 1 1 1 0 NYN domain Topoisom_bac PF01131.15 CBZ26172.1 - 1.3e-95 320.5 0.0 2e-95 320.0 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CBZ26172.1 - 2.1e-15 56.4 0.0 4.2e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-GRF PF06839.7 CBZ26172.1 - 3.3e-07 30.1 2.6 3.3e-07 30.1 1.8 2.7 2 0 0 2 2 2 1 GRF zinc finger zf-C4_Topoisom PF01396.14 CBZ26172.1 - 1.1e-05 24.8 0.7 1.1e-05 24.8 0.5 4.8 5 0 0 5 5 5 1 Topoisomerase DNA binding C4 zinc finger Lar_restr_allev PF14354.1 CBZ26172.1 - 0.00029 21.0 11.3 0.28 11.5 0.2 4.2 4 0 0 4 4 4 2 Restriction alleviation protein Lar HypA PF01155.14 CBZ26172.1 - 6.3 6.5 14.3 1.6 8.4 0.4 4.0 3 1 0 3 3 3 0 Hydrogenase expression/synthesis hypA family 14-3-3 PF00244.15 CBZ26173.1 - 1e-91 306.2 2.0 1.2e-91 306.0 1.4 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 CBZ26173.1 - 0.012 15.5 4.6 0.04 13.8 0.6 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ26173.1 - 7.7 6.7 6.6 5.4 7.1 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Matrilin_ccoil PF10393.4 CBZ26174.1 - 0.012 14.9 0.6 0.012 14.9 0.4 4.7 5 0 0 5 5 5 0 Trimeric coiled-coil oligomerisation domain of matrilin CbiG_mid PF11761.3 CBZ26174.1 - 0.04 14.1 0.6 0.22 11.7 0.4 2.3 1 0 0 1 1 1 0 Cobalamin biosynthesis central region GMC_oxred_N PF00732.14 CBZ26175.1 - 5.4e-48 163.6 0.0 9.4e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 CBZ26175.1 - 3.1e-20 72.9 0.0 6.2e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 CBZ26175.1 - 1.8e-09 37.0 0.1 0.00023 20.2 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBZ26175.1 - 2.2e-08 33.3 7.1 0.00041 19.3 1.4 3.1 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 CBZ26175.1 - 1e-05 25.5 0.0 0.00013 21.9 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ26175.1 - 0.0018 18.2 1.3 0.0084 16.1 0.9 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CBZ26175.1 - 0.0098 14.7 1.3 0.26 10.1 1.4 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 CBZ26175.1 - 0.014 14.3 0.8 0.014 14.3 0.5 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 CBZ26175.1 - 0.03 12.8 2.2 0.044 12.2 0.7 1.7 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 CBZ26175.1 - 0.091 12.8 0.0 0.91 9.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBZ26175.1 - 0.097 11.7 3.7 0.69 8.9 1.8 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1712 PF08217.6 CBZ26178.1 - 0.00014 20.3 0.0 0.0002 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Ribosomal_L22e PF01776.12 CBZ26180.1 - 1.3e-39 134.7 3.8 1.6e-39 134.4 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family ECH PF00378.15 CBZ26181.1 - 2.2e-12 46.6 0.0 1.3e-07 31.0 0.0 2.4 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CBZ26181.1 - 1.5e-10 41.2 0.0 5.3e-07 29.8 0.0 3.8 3 0 0 3 3 3 2 2-enoyl-CoA Hydratase C-terminal region UMP1 PF05348.6 CBZ26181.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 Macro PF01661.16 CBZ26182.1 - 0.00012 21.9 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Macro domain Equine_IAV_S2 PF06502.6 CBZ26183.1 - 0.23 11.3 1.3 0.66 9.8 0.9 1.7 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein Actin PF00022.14 CBZ26184.1 - 2.7e-99 332.2 0.0 3e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 Actin DUF3595 PF12166.3 CBZ26187.1 - 6.2e-117 390.9 0.0 9.1e-117 390.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) Bromodomain PF00439.20 CBZ26189.1 - 5e-14 51.9 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Bromodomain YtzH PF14165.1 CBZ26189.1 - 0.019 15.1 0.1 0.06 13.5 0.0 1.9 2 0 0 2 2 2 0 YtzH-like protein Ribosomal_L29e PF01779.12 CBZ26192.1 - 2.1e-17 62.6 7.4 2.1e-17 62.6 5.1 1.8 2 0 0 2 2 2 1 Ribosomal L29e protein family Tymo_45kd_70kd PF03251.8 CBZ26192.1 - 0.0009 18.0 0.1 0.00097 17.9 0.1 1.1 1 0 0 1 1 1 1 Tymovirus 45/70Kd protein Spo7_2_N PF15407.1 CBZ26192.1 - 0.065 12.7 0.3 0.095 12.1 0.2 1.5 1 1 0 1 1 1 0 Sporulation protein family 7 HTH_Tnp_Mu_2 PF09039.6 CBZ26192.1 - 0.094 12.4 0.1 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain YihI PF04220.7 CBZ26192.1 - 0.12 11.7 1.8 0.18 11.0 1.3 1.4 1 1 0 1 1 1 0 Der GTPase activator (YihI) Ribosomal_L29e PF01779.12 CBZ26193.1 - 2.1e-17 62.6 7.4 2.1e-17 62.6 5.1 1.8 2 0 0 2 2 2 1 Ribosomal L29e protein family Tymo_45kd_70kd PF03251.8 CBZ26193.1 - 0.0009 18.0 0.1 0.00097 17.9 0.1 1.1 1 0 0 1 1 1 1 Tymovirus 45/70Kd protein Spo7_2_N PF15407.1 CBZ26193.1 - 0.065 12.7 0.3 0.095 12.1 0.2 1.5 1 1 0 1 1 1 0 Sporulation protein family 7 HTH_Tnp_Mu_2 PF09039.6 CBZ26193.1 - 0.094 12.4 0.1 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Mu DNA binding, I gamma subdomain YihI PF04220.7 CBZ26193.1 - 0.12 11.7 1.8 0.18 11.0 1.3 1.4 1 1 0 1 1 1 0 Der GTPase activator (YihI) adh_short PF00106.20 CBZ26194.1 - 2.3e-23 82.9 0.1 5e-23 81.8 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBZ26194.1 - 1.7e-10 40.8 1.4 2.4e-09 37.1 1.0 2.2 1 1 0 1 1 1 1 KR domain Methyltransf_31 PF13847.1 CBZ26194.1 - 8.4e-05 22.2 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ26194.1 - 0.034 13.2 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family 3HCDH_N PF02737.13 CBZ26194.1 - 0.079 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CBZ26194.1 - 0.16 12.3 0.3 0.29 11.5 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Vps26 PF03643.10 CBZ26195.1 - 2.4e-53 180.7 0.7 2.9e-53 180.4 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CBZ26195.1 - 1.6e-05 24.7 1.3 0.0089 15.8 0.4 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CRAL_TRIO PF00650.15 CBZ26196.1 - 6.1e-29 100.5 0.0 8.7e-29 100.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CBZ26196.1 - 0.0009 19.1 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Snf7 PF03357.16 CBZ26197.1 - 1.7e-26 92.6 30.4 1.7e-26 92.6 21.1 2.0 1 1 1 2 2 2 2 Snf7 Glyco_transf_25 PF01755.12 CBZ26198.1 - 4.9e-13 49.1 0.0 1.2e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) NIPSNAP PF07978.8 CBZ26199.1 - 2.1e-14 53.3 0.0 3.6e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 NIPSNAP Transket_pyr PF02779.19 CBZ26200.1 - 7.1e-56 188.5 0.0 4.6e-55 185.8 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CBZ26200.1 - 4.2e-50 170.1 0.0 7.1e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component SMAP PF15477.1 CBZ26201.1 - 1.5e-12 47.5 4.7 1.5e-12 47.5 3.3 2.4 2 1 0 2 2 2 1 Small acidic protein family Bac_globin PF01152.16 CBZ26201.1 - 0.19 11.7 1.1 0.35 10.8 0.1 1.8 2 0 0 2 2 2 0 Bacterial-like globin DUF4200 PF13863.1 CBZ26201.1 - 0.51 10.2 4.1 0.21 11.5 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF2870 PF11069.3 CBZ26202.1 - 7.3e-29 99.7 0.0 1.6e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) DivIC PF04977.10 CBZ26203.1 - 0.027 13.9 0.1 0.027 13.9 0.1 3.0 3 0 0 3 3 3 0 Septum formation initiator HALZ PF02183.13 CBZ26203.1 - 0.035 13.8 2.7 0.081 12.6 0.1 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 CBZ26203.1 - 0.25 11.6 8.6 0.55 10.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Dscam_C PF12355.3 CBZ26204.1 - 0.08 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal DUF2150 PF09920.4 CBZ26205.1 - 0.15 11.6 0.1 0.49 9.9 0.0 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) ubiquitin PF00240.18 CBZ26206.1 - 1.6e-34 117.0 0.3 1.8e-34 116.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ26206.1 - 5.9e-18 64.3 0.1 6.7e-18 64.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ26206.1 - 2.8e-06 27.4 0.0 1.4e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBZ26206.1 - 0.007 16.0 0.0 0.0071 16.0 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBZ26206.1 - 0.007 16.2 0.0 0.016 15.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 CBZ26206.1 - 0.037 14.0 0.0 0.083 12.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 CBZ26206.1 - 0.071 13.0 0.0 0.088 12.7 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG DUF2407 PF10302.4 CBZ26206.1 - 0.083 13.0 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain SQS_PSY PF00494.14 CBZ26209.1 - 4.4e-13 49.1 0.0 7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase SRP54 PF00448.17 CBZ26210.1 - 2.3e-54 183.8 0.1 5.6e-54 182.5 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 CBZ26210.1 - 1.5e-21 77.0 0.2 2.5e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 CBZ26210.1 - 9e-06 25.7 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.1 CBZ26210.1 - 1.2e-05 25.4 0.1 6.2e-05 23.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBZ26210.1 - 8.7e-05 22.1 0.3 8.7e-05 22.1 0.2 1.7 2 0 0 2 2 1 1 AAA domain APS_kinase PF01583.15 CBZ26210.1 - 0.00041 20.0 0.1 0.0052 16.4 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase ETF PF01012.16 CBZ26210.1 - 0.00058 19.6 0.8 0.055 13.1 0.0 2.5 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ArgK PF03308.11 CBZ26210.1 - 0.0012 17.6 0.1 0.0036 16.1 0.0 1.7 2 0 0 2 2 2 1 ArgK protein DAP3 PF10236.4 CBZ26210.1 - 0.0016 17.4 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CBZ26210.1 - 0.0019 18.2 0.1 0.0076 16.2 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 CBZ26210.1 - 0.01 15.5 0.2 3.6 7.2 0.0 3.2 3 0 0 3 3 3 0 NACHT domain AAA_10 PF12846.2 CBZ26210.1 - 0.012 15.0 0.1 0.08 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 CBZ26210.1 - 0.013 14.5 0.0 0.067 12.2 0.0 2.2 2 1 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.18 CBZ26210.1 - 0.019 14.9 0.0 0.11 12.5 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 CBZ26210.1 - 0.019 14.6 0.0 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 NTPase CbiA PF01656.18 CBZ26210.1 - 0.031 13.6 0.1 0.3 10.4 0.1 2.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 CBZ26210.1 - 0.068 12.6 0.1 0.16 11.3 0.1 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ArsA_ATPase PF02374.10 CBZ26210.1 - 0.077 12.0 0.5 0.21 10.6 0.1 1.9 2 0 0 2 2 2 0 Anion-transporting ATPase ABC_tran PF00005.22 CBZ26210.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.12 CBZ26210.1 - 0.12 11.6 0.0 0.43 9.9 0.0 1.9 1 0 0 1 1 1 0 Thymidylate kinase Exo70 PF03081.10 CBZ26210.1 - 0.19 10.4 0.1 0.34 9.6 0.1 1.3 1 0 0 1 1 1 0 Exo70 exocyst complex subunit DUF2009 PF09418.5 CBZ26211.1 - 1.4e-112 376.8 2.4 1.3e-111 373.6 1.7 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2009) PALP PF00291.20 CBZ26212.1 - 1.1e-55 188.9 0.4 1.3e-55 188.8 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NuiA PF07924.6 CBZ26213.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein EF-hand_8 PF13833.1 CBZ26215.1 - 1.5e-08 34.1 0.4 0.003 17.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 CBZ26215.1 - 7.2e-07 29.2 1.1 4.4e-06 26.7 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ26215.1 - 0.00011 21.2 0.6 0.016 14.4 0.0 3.2 3 1 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CBZ26215.1 - 0.001 18.7 0.1 0.028 14.2 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 CBZ26215.1 - 0.021 14.1 0.0 0.055 12.8 0.0 1.7 1 0 0 1 1 1 0 EF hand TMEM51 PF15345.1 CBZ26216.1 - 0.001 18.8 1.2 0.001 18.8 0.8 1.4 2 0 0 2 2 2 1 Transmembrane protein 51 Shisa PF13908.1 CBZ26216.1 - 0.0014 18.7 0.2 0.0014 18.7 0.2 2.1 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator IncA PF04156.9 CBZ26216.1 - 0.0019 17.8 5.4 0.003 17.1 3.8 1.3 1 0 0 1 1 1 1 IncA protein Herpes_gE PF02480.11 CBZ26216.1 - 0.0025 16.1 0.1 0.0032 15.8 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E AJAP1_PANP_C PF15298.1 CBZ26216.1 - 0.0092 15.8 0.9 0.014 15.3 0.1 1.7 1 1 0 1 1 1 1 AJAP1/PANP C-terminus DUF4448 PF14610.1 CBZ26216.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.1 CBZ26216.1 - 0.017 14.8 0.0 0.033 13.8 0.0 1.6 1 1 0 1 1 1 0 TMEM154 protein family DAG1 PF05454.6 CBZ26216.1 - 0.023 13.8 0.8 0.033 13.3 0.0 1.6 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) BatD PF13584.1 CBZ26216.1 - 0.035 12.7 0.0 0.042 12.4 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance MAS20 PF02064.10 CBZ26216.1 - 0.039 13.8 2.0 0.064 13.1 1.4 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor TMEM52 PF14979.1 CBZ26216.1 - 0.048 13.5 1.7 0.078 12.8 0.0 2.1 2 0 0 2 2 2 0 Transmembrane 52 Adeno_E3_CR2 PF02439.10 CBZ26216.1 - 0.13 11.8 3.3 0.24 10.9 2.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF106 PF01956.11 CBZ26216.1 - 0.26 10.8 1.4 0.4 10.1 0.9 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Phage_int_SAM_5 PF13102.1 CBZ26216.1 - 1.5 8.8 4.6 2.5 8.0 3.2 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain DUF3157 PF11355.3 CBZ26217.1 - 0.061 12.5 0.0 0.066 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) WD40 PF00400.27 CBZ26218.1 - 2.6e-14 52.4 13.8 6e-05 22.7 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF1619 PF07773.6 CBZ26220.1 - 4.2e-80 269.6 1.5 8.7e-78 262.0 0.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) NUDIX PF00293.23 CBZ26221.1 - 1.7e-11 43.9 0.0 2.8e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain EF-hand_1 PF00036.27 CBZ26223.1 - 2.1e-26 89.1 6.4 4.6e-07 28.6 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CBZ26223.1 - 5.5e-25 87.2 2.2 4.9e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ26223.1 - 1.8e-21 73.9 4.3 7.4e-06 25.4 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CBZ26223.1 - 3.6e-19 68.1 6.7 1.8e-10 40.2 0.5 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBZ26223.1 - 4.7e-18 63.6 5.6 1.7e-05 23.9 0.6 4.5 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 CBZ26223.1 - 2.8e-07 30.3 0.5 0.028 14.3 0.0 2.9 2 2 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBZ26223.1 - 2.9e-05 23.7 1.6 0.013 15.2 0.1 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.20 CBZ26224.1 - 1.1e-53 182.0 0.0 1.4e-52 178.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26224.1 - 1.2e-29 103.2 0.0 4.9e-29 101.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ26224.1 - 0.00097 18.1 0.0 0.0032 16.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PAS PF00989.19 CBZ26224.1 - 0.0014 18.3 0.0 0.0058 16.4 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 CBZ26224.1 - 0.0019 18.5 0.0 0.0063 16.8 0.0 1.9 1 0 0 1 1 1 1 PAS domain RIO1 PF01163.17 CBZ26224.1 - 0.0035 16.7 0.0 0.032 13.5 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CBZ26224.1 - 0.017 14.8 0.0 0.044 13.5 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family PMP22_Claudin PF00822.15 CBZ26224.1 - 0.093 12.3 2.4 0.21 11.2 1.7 1.5 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family FtsK_SpoIIIE PF01580.13 CBZ26227.1 - 0.00024 20.6 0.0 0.0005 19.5 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Clp1 PF06807.9 CBZ26227.1 - 0.0037 17.0 0.0 0.0081 15.9 0.0 1.5 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 DUF498 PF04430.9 CBZ26228.1 - 5.1e-23 80.7 0.0 8.8e-23 79.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Pec_lyase_N PF04431.8 CBZ26228.1 - 0.14 12.2 1.3 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Pectate lyase, N terminus tRNA_int_endo PF01974.12 CBZ26229.1 - 1.1e-13 50.7 0.0 1.6e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Ribosomal_L34e PF01199.13 CBZ26230.1 - 1.3e-27 95.8 4.0 1.3e-27 95.8 2.8 2.3 2 1 0 2 2 2 1 Ribosomal protein L34e Mucin PF01456.12 CBZ26230.1 - 0.11 12.2 1.2 0.16 11.7 0.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein NARP1 PF12569.3 CBZ26230.1 - 0.4 9.3 8.2 0.44 9.2 5.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ribosomal_S27e PF01667.12 CBZ26231.1 - 8.4e-22 76.4 3.1 1.1e-21 76.1 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CBZ26231.1 - 0.0011 18.8 1.5 0.0015 18.3 1.0 1.2 1 0 0 1 1 1 1 IBR domain FYVE_2 PF02318.11 CBZ26231.1 - 0.0085 15.9 1.4 0.01 15.7 1.0 1.1 1 0 0 1 1 1 1 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.2 CBZ26231.1 - 0.0091 15.7 2.0 0.014 15.2 1.4 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Cbl_N3 PF02762.9 CBZ26231.1 - 0.047 13.3 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain HypA PF01155.14 CBZ26231.1 - 0.11 12.1 1.4 0.14 11.8 1.0 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 CBZ26231.1 - 0.18 11.5 4.4 3.2 7.5 3.1 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Elf1 PF05129.8 CBZ26231.1 - 0.19 11.4 2.9 0.27 10.9 2.0 1.2 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 CBZ26231.1 - 0.3 10.6 4.6 4.5 6.9 3.2 2.3 1 1 0 1 1 1 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 CBZ26231.1 - 0.32 10.5 7.8 2.2 7.8 5.4 2.2 1 1 0 1 1 1 0 InsA N-terminal domain Mu-like_Com PF10122.4 CBZ26231.1 - 0.39 9.7 6.7 0.36 9.9 0.1 2.3 1 1 1 2 2 2 0 Mu-like prophage protein Com OrfB_Zn_ribbon PF07282.6 CBZ26231.1 - 1.7 8.3 6.5 1.1 8.9 1.6 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L1 PF00687.16 CBZ26232.1 - 5.3e-47 159.9 3.2 6.2e-47 159.7 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NAC PF01849.13 CBZ26233.1 - 7.1e-19 67.0 0.0 9.5e-19 66.6 0.0 1.2 1 0 0 1 1 1 1 NAC domain MORN PF02493.15 CBZ26234.1 - 1.4e-16 59.1 61.0 4.9e-05 22.8 0.8 9.4 10 0 0 10 10 10 7 MORN repeat DUF448 PF04296.8 CBZ26234.1 - 0.0021 17.6 0.3 3.4 7.3 0.0 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF448) DUF2766 PF10964.3 CBZ26234.1 - 0.068 13.0 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2766) CH PF00307.26 CBZ26235.1 - 0.00021 21.3 0.0 0.00049 20.1 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain ADIP PF11559.3 CBZ26235.1 - 0.00062 19.6 5.4 0.00062 19.6 3.8 2.9 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding IMS PF00817.15 CBZ26235.1 - 0.0022 17.7 0.4 0.0057 16.4 0.3 1.6 1 0 0 1 1 1 1 impB/mucB/samB family Tropomyosin_1 PF12718.2 CBZ26235.1 - 0.0096 15.7 5.1 0.0096 15.7 3.5 2.6 3 0 0 3 3 3 1 Tropomyosin like GAS PF13851.1 CBZ26235.1 - 0.053 12.7 2.8 0.19 10.8 2.0 1.9 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CAMSAP_CH PF11971.3 CBZ26235.1 - 0.072 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain DNA_ligase_IV PF11411.3 CBZ26235.1 - 0.099 12.4 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 DNA ligase IV DUF2301 PF10063.4 CBZ26235.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) GCV_T PF01571.16 CBZ26236.1 - 2e-60 203.7 0.3 2.7e-60 203.3 0.2 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CBZ26236.1 - 8.5e-19 67.3 0.1 1.9e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CBZ26236.1 - 0.001 18.9 0.0 0.043 13.6 0.0 2.6 2 1 1 3 3 3 1 Sarcosine oxidase, gamma subunit family GCV_T PF01571.16 CBZ26237.1 - 1.6e-63 213.8 0.3 2.2e-63 213.4 0.2 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CBZ26237.1 - 8.4e-19 67.3 0.1 1.9e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CBZ26237.1 - 0.00043 20.1 0.0 0.022 14.5 0.0 2.6 2 1 1 3 3 3 1 Sarcosine oxidase, gamma subunit family AIP3 PF03915.8 CBZ26238.1 - 0.0058 15.5 0.1 0.0066 15.4 0.1 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 HisKA_3 PF07730.8 CBZ26238.1 - 0.03 14.6 0.7 0.058 13.7 0.5 1.5 1 0 0 1 1 1 0 Histidine kinase DUF1664 PF07889.7 CBZ26238.1 - 0.089 12.5 1.6 0.14 11.9 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 CBZ26238.1 - 0.091 11.6 0.2 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_1 PF00170.16 CBZ26238.1 - 0.13 12.2 3.2 3.4 7.6 0.9 2.2 2 0 0 2 2 2 0 bZIP transcription factor DUF3138 PF11336.3 CBZ26238.1 - 0.18 9.9 0.6 0.21 9.6 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) bZIP_2 PF07716.10 CBZ26238.1 - 0.23 11.3 7.2 1.4 8.8 1.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper zf-C3HC4_3 PF13920.1 CBZ26239.1 - 9.2e-18 63.6 31.4 4.8e-13 48.5 8.2 4.6 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ26239.1 - 2.4e-06 27.4 34.3 3.3e-05 23.8 9.8 4.3 4 1 1 5 5 5 3 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ26239.1 - 7.1e-05 22.4 40.2 0.00015 21.4 8.5 3.8 4 0 0 4 4 4 2 zinc-RING finger domain tRNA-synt_2b PF00587.20 CBZ26240.1 - 3.1e-54 183.1 0.2 5.4e-54 182.3 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBZ26240.1 - 1e-17 63.8 0.0 2.1e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Snf7 PF03357.16 CBZ26241.1 - 7.9e-30 103.4 30.8 7.9e-30 103.4 21.4 1.5 2 0 0 2 2 2 1 Snf7 ODR4-like PF14778.1 CBZ26241.1 - 0.011 14.4 5.0 0.016 13.9 3.4 1.4 1 1 0 1 1 1 0 Olfactory receptor 4-like Noc2 PF03715.8 CBZ26241.1 - 0.063 12.1 1.6 0.078 11.8 1.1 1.2 1 0 0 1 1 1 0 Noc2p family Mst1_SARAH PF11629.3 CBZ26241.1 - 0.069 12.9 0.8 0.069 12.9 0.6 2.7 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Atg14 PF10186.4 CBZ26241.1 - 8.2 5.2 11.9 12 4.6 8.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HAP2-GCS1 PF10699.4 CBZ26242.1 - 1.1e-16 60.5 0.0 1.1e-16 60.5 0.0 1.9 2 0 0 2 2 2 1 Male gamete fusion factor Gasdermin PF04598.7 CBZ26243.1 - 0.00018 20.4 1.8 0.00027 19.8 1.3 1.1 1 0 0 1 1 1 1 Gasdermin family LRR_6 PF13516.1 CBZ26243.1 - 0.071 13.2 0.1 17 5.8 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeat WD40 PF00400.27 CBZ26244.1 - 8.8e-20 69.7 3.1 7.8e-08 31.9 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF982 PF06169.7 CBZ26246.1 - 0.071 12.8 1.0 0.17 11.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF982) AdoHcyase PF05221.12 CBZ26247.1 - 1.8e-142 473.0 0.0 2e-142 472.8 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CBZ26247.1 - 1e-86 288.8 2.7 1.5e-86 288.3 1.9 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CBZ26247.1 - 9.1e-10 37.9 0.0 1.9e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CBZ26247.1 - 0.00012 21.4 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CBZ26247.1 - 0.00025 21.0 0.2 0.0015 18.5 0.1 2.4 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.1 CBZ26247.1 - 0.0017 18.5 0.1 0.004 17.3 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 CBZ26247.1 - 0.0084 15.7 0.1 0.016 14.7 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UDPG_MGDP_dh_N PF03721.9 CBZ26247.1 - 0.15 11.4 0.5 0.24 10.7 0.3 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4282 PF14110.1 CBZ26248.1 - 2.3 8.4 12.5 50 4.1 8.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4282) Telomerase_RBD PF12009.3 CBZ26249.1 - 2.9e-26 92.0 0.1 6e-26 90.9 0.0 1.6 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CBZ26249.1 - 2.3e-05 23.8 0.0 6.3e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Herpes_capsid PF06112.6 CBZ26249.1 - 2.7 8.0 8.7 2.3 8.2 1.4 3.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein TACC PF05010.9 CBZ26251.1 - 0.0003 20.6 8.8 0.0003 20.6 6.1 2.0 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC) Borrelia_REV PF03978.8 CBZ26251.1 - 0.022 14.4 1.8 0.036 13.7 1.3 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein GSCFA PF08885.6 CBZ26251.1 - 0.075 12.5 0.6 0.11 11.9 0.2 1.5 1 1 0 1 1 1 0 GSCFA family IFT46_B_C PF12317.3 CBZ26251.1 - 0.076 12.3 1.8 0.068 12.5 0.5 1.5 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal AAA_13 PF13166.1 CBZ26251.1 - 0.21 10.0 8.4 0.2 10.0 4.7 1.7 1 1 1 2 2 2 0 AAA domain OmpH PF03938.9 CBZ26251.1 - 1.3 8.9 7.8 1.1 9.2 0.0 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Prefoldin PF02996.12 CBZ26251.1 - 1.5 8.5 6.3 2.4 7.8 0.8 3.1 3 0 0 3 3 3 0 Prefoldin subunit Bacillus_HBL PF05791.6 CBZ26251.1 - 1.5 8.1 9.9 1 8.7 0.1 2.9 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CDC73 PF05179.9 CBZ26254.1 - 2e-26 93.0 0.0 2.6e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Proteasome PF00227.21 CBZ26255.1 - 1e-25 90.1 0.3 2.8e-25 88.7 0.2 1.6 1 1 0 1 1 1 1 Proteasome subunit NTP_transf_2 PF01909.18 CBZ26256.1 - 2.1e-07 31.1 0.0 3.5e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Rieske PF00355.21 CBZ26257.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.6 1 1 0 1 1 1 0 Rieske [2Fe-2S] domain V-SNARE_C PF12352.3 CBZ26259.1 - 1.7e-06 28.0 1.0 1.7e-06 28.0 0.7 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Peptidase_M14 PF00246.19 CBZ26260.1 - 3.5e-23 82.6 0.0 8.6e-23 81.3 0.0 1.5 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CBZ26260.1 - 5.8e-06 25.3 0.1 9e-06 24.7 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TPR_11 PF13414.1 CBZ26261.1 - 1.9e-05 24.1 5.2 0.0088 15.6 0.8 2.9 2 1 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 CBZ26261.1 - 6e-05 22.9 10.5 0.4 10.6 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ26261.1 - 0.00011 22.7 11.1 1.8 9.3 0.3 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBZ26261.1 - 0.0013 17.9 1.0 0.0031 16.7 0.7 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.12 CBZ26261.1 - 0.0056 16.5 13.8 0.49 10.4 0.3 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ26261.1 - 0.0067 15.9 4.0 4.1 7.1 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ26261.1 - 0.17 11.7 9.7 1.7 8.5 0.5 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SAPS PF04499.10 CBZ26261.1 - 1 7.9 3.9 1.4 7.4 2.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.11 CBZ26261.1 - 1.1 8.2 11.3 2 7.3 7.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RR_TM4-6 PF06459.7 CBZ26261.1 - 2.8 7.7 15.5 0.44 10.3 7.7 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Di19_C PF14571.1 CBZ26261.1 - 3.8 7.8 12.1 8.3 6.7 6.1 2.5 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal CDC45 PF02724.9 CBZ26261.1 - 5 5.0 14.0 7.6 4.4 9.7 1.2 1 0 0 1 1 1 0 CDC45-like protein TatD_DNase PF01026.16 CBZ26262.1 - 2.7e-28 98.8 0.0 3.3e-27 95.3 0.0 2.1 1 1 0 2 2 2 1 TatD related DNase RCC1 PF00415.13 CBZ26263.1 - 1e-37 128.0 11.1 3.5e-09 36.7 0.0 7.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ26263.1 - 2.1e-20 71.7 21.8 3.7e-06 26.4 2.0 7.2 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat His_Phos_1 PF00300.17 CBZ26264.1 - 1.5e-13 51.1 2.5 7.3e-12 45.6 1.7 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 3HCDH_N PF02737.13 CBZ26264.1 - 0.097 12.3 0.1 0.3 10.6 0.1 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IQ PF00612.22 CBZ26265.1 - 2.9e-12 45.0 14.4 0.00012 21.3 0.4 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif Apc15p PF05841.6 CBZ26266.1 - 1.6 9.4 7.0 2.8 8.6 0.9 2.3 2 0 0 2 2 2 0 Apc15p protein Glyco_hydro_31 PF01055.21 CBZ26267.1 - 1.5e-47 162.4 0.0 3.6e-32 111.7 0.0 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 31 Amastin PF07344.6 CBZ26270.1 - 4.7e-06 26.2 6.1 4.7e-06 26.2 4.2 1.9 2 0 0 2 2 2 1 Amastin surface glycoprotein Amastin PF07344.6 CBZ26271.1 - 1.5e-14 53.9 4.6 2.4e-14 53.2 3.2 1.3 1 1 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 CBZ26271.1 - 0.019 14.6 7.9 0.036 13.7 5.5 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.1 CBZ26271.1 - 0.038 13.6 8.6 0.071 12.7 5.7 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction OAD_gamma PF04277.8 CBZ26271.1 - 0.18 12.1 1.6 0.98 9.8 0.1 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4131 PF13567.1 CBZ26271.1 - 0.54 9.6 5.9 9.3 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SUR7 PF06687.7 CBZ26271.1 - 3 7.3 16.1 42 3.5 10.9 2.4 1 1 0 1 1 1 0 SUR7/PalI family TFIIS_C PF01096.13 CBZ26272.1 - 5.2e-11 41.9 8.4 5.2e-11 41.9 5.8 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF1451 PF07295.6 CBZ26272.1 - 0.004 16.9 0.4 0.004 16.9 0.2 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1451) RIG-I_C-RD PF11648.3 CBZ26272.1 - 0.017 14.9 1.6 9 6.1 0.0 2.9 3 0 0 3 3 3 0 C-terminal domain of RIG-I C1_1 PF00130.17 CBZ26272.1 - 0.028 14.1 0.5 0.028 14.1 0.4 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.1 CBZ26272.1 - 0.16 11.1 7.5 3.9 6.7 0.0 3.7 4 0 0 4 4 4 0 zinc-ribbon domain RNA_POL_M_15KD PF02150.11 CBZ26272.1 - 0.23 11.1 2.6 63 3.3 0.0 3.3 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Terminase_GpA PF05876.7 CBZ26272.1 - 1.1 7.5 4.7 7.9 4.6 0.0 2.1 1 1 0 2 2 2 0 Phage terminase large subunit (GpA) DZR PF12773.2 CBZ26272.1 - 1.5 8.7 12.2 1.5 8.7 0.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon Elf1 PF05129.8 CBZ26272.1 - 2.9 7.6 8.5 1.4 8.6 0.0 3.0 2 2 0 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.14 CBZ26272.1 - 3.3 7.4 9.3 0.82 9.3 0.2 2.5 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Stc1 PF12898.2 CBZ26272.1 - 3.8 7.6 11.7 5.7 7.0 6.0 2.7 1 1 1 2 2 2 0 Stc1 domain Baculo_LEF5_C PF11792.3 CBZ26272.1 - 6.7 6.1 9.2 0.81 9.1 2.8 2.2 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain CorA PF01544.13 CBZ26273.1 - 1.4 7.8 3.9 3.7 6.4 2.7 1.7 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ADH_zinc_N PF00107.21 CBZ26275.1 - 1.1e-36 125.1 0.1 2.9e-36 123.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBZ26275.1 - 4e-15 56.8 0.0 1.3e-14 55.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBZ26275.1 - 7.5e-15 54.6 1.7 1.5e-14 53.6 0.2 2.2 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cpn10 PF00166.16 CBZ26275.1 - 0.0097 15.8 0.8 0.23 11.3 0.0 2.8 3 0 0 3 3 3 1 Chaperonin 10 Kd subunit Semialdhyde_dh PF01118.19 CBZ26275.1 - 0.025 14.8 0.1 0.75 10.1 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 CBZ26275.1 - 0.048 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glycos_transf_4 PF00953.16 CBZ26276.1 - 7.3e-44 149.3 6.6 7.3e-44 149.3 4.5 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 4 Sld5 PF05916.6 CBZ26277.1 - 1.3e-24 86.5 0.0 2e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Arrestin_N PF00339.24 CBZ26278.1 - 2.5e-07 30.6 0.0 4.6e-05 23.2 0.0 3.3 2 1 1 3 3 3 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CBZ26278.1 - 2.7e-05 23.7 0.1 0.00016 21.2 0.0 2.2 3 0 0 3 3 3 1 Arrestin_N terminal like WD40 PF00400.27 CBZ26279.1 - 2.6e-22 77.7 5.4 1.6e-07 30.9 0.0 8.3 9 0 0 9 9 9 4 WD domain, G-beta repeat Utp21 PF04192.7 CBZ26279.1 - 6.6e-18 64.6 0.1 1e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain PQQ_2 PF13360.1 CBZ26279.1 - 1.4e-06 28.0 2.4 0.0012 18.3 0.3 3.1 3 1 0 3 3 3 2 PQQ-like domain Nup160 PF11715.3 CBZ26279.1 - 5.6e-05 21.4 3.7 0.0064 14.6 0.0 4.3 4 1 1 5 5 5 1 Nucleoporin Nup120/160 Utp12 PF04003.7 CBZ26279.1 - 0.079 12.8 0.1 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family LRR_6 PF13516.1 CBZ26281.1 - 1.5e-39 129.5 42.8 0.0042 17.0 0.0 20.7 22 0 0 22 22 22 12 Leucine Rich repeat LRR_4 PF12799.2 CBZ26281.1 - 2.6e-24 84.3 27.6 0.028 14.0 0.3 13.7 8 2 7 16 16 16 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ26281.1 - 2.2e-11 42.1 23.5 18 5.8 0.1 16.9 20 1 0 20 20 20 2 Leucine Rich Repeat LRR_8 PF13855.1 CBZ26281.1 - 2.7e-06 27.0 37.0 0.0095 15.6 0.2 12.6 9 5 5 14 14 14 4 Leucine rich repeat LRR_7 PF13504.1 CBZ26281.1 - 0.00016 21.3 13.7 53 4.6 0.0 11.6 14 0 0 14 14 14 0 Leucine rich repeat WD40 PF00400.27 CBZ26282.1 - 5.5e-11 41.8 6.6 0.00097 18.9 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.20 CBZ26283.1 - 1.7e-47 161.7 0.0 4.9e-24 84.8 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26283.1 - 4.4e-19 68.5 0.0 4.2e-12 45.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ26283.1 - 0.0057 15.6 0.0 0.16 10.8 0.0 2.7 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 CBZ26283.1 - 0.034 13.8 0.1 0.38 10.4 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family TPR_14 PF13428.1 CBZ26286.1 - 3.9e-09 36.3 49.3 0.022 15.3 0.7 12.4 11 2 3 14 14 14 5 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ26286.1 - 6.6e-07 29.5 12.5 0.00076 19.7 0.1 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat HAT PF02184.11 CBZ26286.1 - 1.1e-06 28.3 17.0 0.09 12.5 0.2 5.8 6 0 0 6 6 6 3 HAT (Half-A-TPR) repeat NRDE-2 PF08424.5 CBZ26286.1 - 6.4e-05 21.9 2.8 0.0013 17.6 0.2 3.6 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference DUF2063 PF09836.4 CBZ26286.1 - 0.024 14.6 0.2 0.1 12.6 0.1 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2063) CCP_MauG PF03150.9 CBZ26286.1 - 0.059 13.6 1.7 0.21 11.8 0.0 2.7 3 0 0 3 3 3 0 Di-haem cytochrome c peroxidase TPR_16 PF13432.1 CBZ26286.1 - 0.36 11.5 46.6 0.14 12.8 1.0 8.8 8 2 0 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ26286.1 - 2.4 8.5 6.7 60 4.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Arf PF00025.16 CBZ26287.1 - 1.1e-11 44.2 0.0 2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PH PF00169.24 CBZ26287.1 - 0.001 19.2 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 PH domain MMR_HSR1 PF01926.18 CBZ26287.1 - 0.0076 16.1 0.0 0.026 14.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PH_8 PF15409.1 CBZ26287.1 - 0.023 14.7 0.2 0.11 12.5 0.1 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain CHAP PF05257.11 CBZ26288.1 - 3.4e-13 49.3 0.3 8.3e-13 48.0 0.2 1.6 1 0 0 1 1 1 1 CHAP domain SET PF00856.23 CBZ26289.1 - 1.9e-09 38.0 0.0 1e-08 35.6 0.0 2.1 1 1 0 1 1 1 1 SET domain AWPM-19 PF05512.6 CBZ26289.1 - 0.22 11.5 2.0 14 5.6 0.5 2.6 1 1 1 2 2 2 0 AWPM-19-like family C2 PF00168.25 CBZ26290.1 - 1.3e-33 114.6 0.1 4.3e-10 39.2 0.0 5.7 6 0 0 6 6 6 4 C2 domain CEP76-C2 PF15627.1 CBZ26290.1 - 0.045 13.2 0.2 0.57 9.6 0.0 2.4 2 0 0 2 2 2 0 CEP76 C2 domain C2 PF00168.25 CBZ26291.1 - 2.6e-11 43.2 0.0 0.00066 19.4 0.0 4.5 4 0 0 4 4 4 4 C2 domain Adeno_PIX PF03955.9 CBZ26292.1 - 3.6 8.1 14.7 0.67 10.5 0.4 4.0 3 2 1 4 4 4 0 Adenovirus hexon-associated protein (IX) AAA PF00004.24 CBZ26294.1 - 4.8e-44 149.7 0.0 1e-43 148.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ26294.1 - 6.4e-08 32.4 0.1 2.4e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBZ26294.1 - 8.1e-07 29.1 0.0 2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBZ26294.1 - 1.3e-06 28.5 0.1 2.8e-05 24.2 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ26294.1 - 3.9e-06 27.0 0.9 0.00031 20.9 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ26294.1 - 1.5e-05 24.6 1.5 0.00038 20.1 0.2 2.7 2 1 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 CBZ26294.1 - 2.5e-05 23.4 0.0 5.8e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBZ26294.1 - 6.7e-05 23.6 0.1 0.00028 21.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBZ26294.1 - 0.00018 20.9 0.0 0.00049 19.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CBZ26294.1 - 0.00065 19.6 0.0 0.0028 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBZ26294.1 - 0.0014 18.4 0.1 0.0035 17.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CBZ26294.1 - 0.0017 17.7 0.6 0.14 11.5 0.0 2.8 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CBZ26294.1 - 0.0021 17.1 0.1 0.0054 15.8 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin KaiC PF06745.8 CBZ26294.1 - 0.0024 17.0 0.2 0.084 11.9 0.0 2.6 3 0 0 3 3 3 1 KaiC NB-ARC PF00931.17 CBZ26294.1 - 0.0025 16.7 0.0 0.055 12.3 0.0 2.3 1 1 1 2 2 2 1 NB-ARC domain TIP49 PF06068.8 CBZ26294.1 - 0.0032 16.2 0.0 0.011 14.5 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_28 PF13521.1 CBZ26294.1 - 0.0032 17.4 0.3 0.0071 16.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CBZ26294.1 - 0.0042 17.3 0.2 0.024 14.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CBZ26294.1 - 0.0058 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBZ26294.1 - 0.0064 15.9 0.9 0.051 13.0 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CBZ26294.1 - 0.0069 15.5 0.0 0.023 13.8 0.0 1.8 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CBZ26294.1 - 0.0071 16.3 0.1 0.13 12.3 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 CBZ26294.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 CBZ26294.1 - 0.011 15.3 0.1 0.033 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 CBZ26294.1 - 0.016 14.4 0.1 0.062 12.5 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.8 CBZ26294.1 - 0.022 13.6 0.2 0.048 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 CBZ26294.1 - 0.04 12.7 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 CBZ26294.1 - 0.044 13.4 0.0 0.59 9.7 0.0 2.3 1 1 0 2 2 2 0 NACHT domain ADIP PF11559.3 CBZ26294.1 - 0.051 13.4 2.2 0.1 12.5 1.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DASH_Dad2 PF08654.5 CBZ26294.1 - 0.069 13.1 0.5 0.19 11.7 0.3 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad2 DUF2968 PF11180.3 CBZ26294.1 - 0.23 10.8 1.8 0.48 9.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) HECT PF00632.20 CBZ26295.1 - 6.7e-63 212.7 0.0 9.4e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AOX PF01786.12 CBZ26296.1 - 1.2e-82 276.2 0.0 1.6e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase Spc97_Spc98 PF04130.8 CBZ26297.1 - 2e-85 287.1 0.0 2.6e-85 286.7 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF309 PF03745.9 CBZ26297.1 - 0.0078 15.6 0.2 0.042 13.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF309) Gemin7 PF11095.3 CBZ26297.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DEAD PF00270.24 CBZ26298.1 - 2.6e-34 118.1 0.2 2.4e-33 115.0 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ26298.1 - 9.7e-25 86.2 0.1 4.7e-24 84.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 CBZ26298.1 - 0.0039 16.5 0.0 2.6 7.2 0.0 2.7 2 0 0 2 2 2 2 SecA DEAD-like domain AAA_22 PF13401.1 CBZ26298.1 - 0.048 13.8 4.4 2.8 8.1 0.0 4.3 5 1 1 6 6 6 0 AAA domain ResIII PF04851.10 CBZ26298.1 - 0.075 12.8 2.9 0.1 12.4 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CAF-1_p150 PF11600.3 CBZ26299.1 - 0.0041 16.5 18.6 0.0051 16.2 12.9 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SET PF00856.23 CBZ26299.1 - 0.29 11.4 1.7 0.33 11.2 1.2 1.1 1 0 0 1 1 1 0 SET domain PBP_sp32 PF07222.7 CBZ26299.1 - 1.2 8.2 8.0 1.4 7.9 5.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 HAUS6_N PF14661.1 CBZ26299.1 - 5.1 6.3 12.6 6.5 6.0 8.7 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Ycf1 PF05758.7 CBZ26299.1 - 7.2 4.1 8.7 8.1 4.0 6.0 1.0 1 0 0 1 1 1 0 Ycf1 Ribosomal_L22e PF01776.12 CBZ26300.1 - 1.3e-39 134.7 3.8 1.6e-39 134.4 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family Asparaginase PF00710.15 CBZ26301.1 - 5.1e-66 222.6 0.0 5.7e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Asparaginase TPR_17 PF13431.1 CBZ26302.1 - 1.6e-06 27.8 5.1 0.00057 19.8 0.4 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ26302.1 - 2.5e-05 24.5 0.1 0.0081 16.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ26302.1 - 5.8e-05 22.6 0.3 0.0016 18.0 0.1 2.9 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 CBZ26302.1 - 0.00027 21.3 2.0 0.29 11.8 0.4 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ26302.1 - 0.00073 19.2 2.1 0.0016 18.2 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ26302.1 - 0.0047 17.5 0.2 0.078 13.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ26302.1 - 0.0077 15.8 1.7 0.042 13.4 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ26302.1 - 0.0091 15.9 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ26302.1 - 0.024 15.0 0.6 0.098 13.1 0.4 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ26302.1 - 0.031 14.7 0.4 0.12 12.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ26302.1 - 0.037 13.8 0.1 0.33 10.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ26302.1 - 0.065 13.0 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ26302.1 - 0.17 12.0 0.2 0.17 12.0 0.2 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_M3 PF01432.15 CBZ26303.1 - 2e-72 244.7 0.1 6.3e-58 196.9 0.1 2.0 2 0 0 2 2 2 2 Peptidase family M3 DnaJ PF00226.26 CBZ26305.1 - 6.1e-24 83.5 0.1 1.5e-23 82.2 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain ATP11 PF06644.6 CBZ26305.1 - 2.8 7.3 6.7 5.9 6.2 0.0 2.3 2 0 0 2 2 2 0 ATP11 protein Aa_trans PF01490.13 CBZ26306.1 - 1e-45 155.9 0.4 2.5e-37 128.3 0.0 2.5 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein Methyltransf_26 PF13659.1 CBZ26307.1 - 1.7e-14 53.8 0.0 3.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ26307.1 - 2e-12 46.8 0.0 3.5e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CBZ26307.1 - 1.3e-10 41.0 0.0 5.7e-10 38.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ26307.1 - 9.7e-09 35.7 0.0 2.6e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBZ26307.1 - 4.6e-07 29.2 0.0 9.8e-07 28.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 CBZ26307.1 - 0.00012 21.2 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 CBZ26307.1 - 0.00022 21.5 0.0 0.00045 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ26307.1 - 0.00028 21.3 0.0 0.0016 18.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 CBZ26307.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 CBZ26307.1 - 0.0053 16.3 1.1 2.9 7.4 0.0 2.5 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 CBZ26307.1 - 0.016 15.6 0.0 0.057 13.9 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 CBZ26307.1 - 0.028 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.1 CBZ26307.1 - 0.036 13.7 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 CBZ26307.1 - 0.042 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 CBZ26307.1 - 0.11 11.8 0.2 0.89 8.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical protein 95 TRM PF02005.11 CBZ26307.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_32 PF13679.1 CBZ26307.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2870 PF11069.3 CBZ26308.1 - 3.6e-37 126.3 0.1 7e-37 125.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Ribosomal_L18e PF00828.14 CBZ26309.1 - 7.6e-21 74.8 0.2 7.6e-21 74.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Alpha_kinase PF02816.13 CBZ26312.1 - 9.3e-57 191.7 0.1 1.2e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family Alpha_kinase PF02816.13 CBZ26313.1 - 4.3e-82 274.3 0.0 9.4e-44 149.3 0.0 3.2 3 0 0 3 3 3 3 Alpha-kinase family ERp29 PF07749.7 CBZ26313.1 - 0.14 12.8 0.0 0.36 11.4 0.0 1.6 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Alpha_kinase PF02816.13 CBZ26314.1 - 6.1e-66 221.6 0.2 7.6e-66 221.3 0.2 1.1 1 0 0 1 1 1 1 Alpha-kinase family PSP1 PF04468.7 CBZ26315.1 - 6.7e-30 102.9 0.6 6.7e-30 102.9 0.4 1.7 2 0 0 2 2 2 1 PSP1 C-terminal conserved region DASH_Spc34 PF08657.5 CBZ26315.1 - 0.12 12.0 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Spc34 BBS2_N PF14781.1 CBZ26317.1 - 0.0035 16.9 0.0 1.8 8.2 0.0 2.8 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal zf-HC5HC2H PF13771.1 CBZ26318.1 - 1.2e-07 31.7 9.7 1.2e-07 31.7 6.7 3.4 4 0 0 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CBZ26318.1 - 3.9e-06 26.8 10.7 3.9e-06 26.8 7.5 3.5 3 1 0 4 4 4 1 PHD-zinc-finger like domain Transmemb_17 PF09799.4 CBZ26319.1 - 6.1e-11 42.6 10.5 8.1e-11 42.2 7.3 1.2 1 0 0 1 1 1 1 Predicted membrane protein SNARE PF05739.14 CBZ26320.1 - 4.2e-05 23.1 1.3 0.00014 21.4 0.9 1.9 1 0 0 1 1 1 1 SNARE domain FliJ PF02050.11 CBZ26320.1 - 0.19 11.8 11.5 7.6 6.6 5.6 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein DUF1244 PF06844.6 CBZ26321.1 - 0.053 13.3 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Ham1p_like PF01725.11 CBZ26322.1 - 8.9e-55 184.9 0.0 1e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_S9 PF00326.16 CBZ26323.1 - 7.8e-09 35.0 0.5 9.9e-07 28.1 0.2 3.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CBZ26323.1 - 1.4e-08 34.4 0.0 4.5e-07 29.5 0.0 2.7 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBZ26323.1 - 2.6e-08 33.7 0.1 7.4e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 CBZ26323.1 - 2.6e-07 30.1 2.2 1.7e-06 27.4 1.5 2.2 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 CBZ26323.1 - 9.9e-07 28.8 1.5 0.00031 20.6 0.1 3.5 3 1 0 3 3 3 1 Alpha/beta hydrolase family Esterase PF00756.15 CBZ26323.1 - 1.4e-05 24.6 0.2 0.00013 21.5 0.1 2.1 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.8 CBZ26323.1 - 0.00013 21.4 0.0 0.00035 20.0 0.0 1.7 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 CBZ26323.1 - 0.0014 18.2 0.1 0.0053 16.3 0.1 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 CBZ26323.1 - 0.0018 17.8 0.5 0.0081 15.7 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 CBZ26323.1 - 0.059 12.6 0.6 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Macro_2 PF14519.1 CBZ26323.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Macro-like domain Ribosomal_L10 PF00466.15 CBZ26324.1 - 8.3e-19 67.3 0.2 1.2e-18 66.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 VPS9 PF02204.13 CBZ26325.1 - 7.1e-30 103.1 0.0 5.7e-29 100.2 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Prok-TraM PF09228.5 CBZ26325.1 - 0.045 13.8 0.5 10 6.3 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic Transcriptional repressor TraM HALZ PF02183.13 CBZ26326.1 - 0.0048 16.5 2.2 0.0099 15.5 0.1 2.4 2 1 0 2 2 2 1 Homeobox associated leucine zipper DUF904 PF06005.7 CBZ26326.1 - 0.0064 16.7 9.3 0.75 10.1 6.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF904) Transcrip_act PF04949.8 CBZ26326.1 - 0.0097 15.5 3.4 0.011 15.3 2.3 1.0 1 0 0 1 1 1 1 Transcriptional activator DUF1042 PF06294.6 CBZ26326.1 - 0.023 14.2 0.7 0.036 13.6 0.5 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1042) IncA PF04156.9 CBZ26326.1 - 0.036 13.6 6.0 0.047 13.2 4.1 1.1 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 CBZ26326.1 - 0.04 13.7 9.4 1.3 8.9 0.1 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3138 PF11336.3 CBZ26326.1 - 0.067 11.3 0.2 0.065 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FUSC PF04632.7 CBZ26326.1 - 0.18 10.1 2.8 0.2 10.0 1.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 CBZ26326.1 - 0.25 11.6 6.5 0.45 10.8 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4055 PF13264.1 CBZ26326.1 - 0.27 11.3 4.2 0.62 10.1 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4055) Toxin_44 PF15523.1 CBZ26326.1 - 0.42 10.5 2.5 0.34 10.8 0.6 1.7 1 1 1 2 2 2 0 Putative toxin 44 GAS PF13851.1 CBZ26326.1 - 0.45 9.6 6.6 0.6 9.2 4.6 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 CBZ26326.1 - 0.45 8.8 2.7 0.65 8.3 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlaC_arch PF05377.6 CBZ26326.1 - 0.51 10.2 1.9 4.8 7.1 0.0 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) ALMS_motif PF15309.1 CBZ26326.1 - 0.52 10.1 5.0 0.5 10.2 1.3 2.0 2 0 0 2 2 2 0 ALMS motif DUF4201 PF13870.1 CBZ26326.1 - 1.1 8.6 9.8 2.9 7.2 6.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) COG2 PF06148.6 CBZ26326.1 - 1.2 8.9 5.1 0.92 9.3 0.9 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 CBZ26326.1 - 1.3 8.7 7.0 3.4 7.4 4.4 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Enkurin PF13864.1 CBZ26326.1 - 1.3 9.2 7.3 0.16 12.2 0.8 2.0 1 1 1 2 2 2 0 Calmodulin-binding TSC22 PF01166.13 CBZ26326.1 - 1.7 8.6 5.3 2.3 8.2 1.2 2.5 2 1 0 2 2 2 0 TSC-22/dip/bun family APG6 PF04111.7 CBZ26326.1 - 2 7.3 6.5 2.6 7.0 4.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CCDC-167 PF15188.1 CBZ26326.1 - 2.2 8.2 9.7 1.2 9.1 0.2 2.3 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4140 PF13600.1 CBZ26326.1 - 2.3 8.6 7.7 2.5 8.5 1.2 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) XhlA PF10779.4 CBZ26326.1 - 3.6 7.5 5.2 15 5.6 0.4 2.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF2968 PF11180.3 CBZ26326.1 - 3.9 6.8 8.9 82 2.4 6.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) bZIP_2 PF07716.10 CBZ26326.1 - 4.6 7.1 12.5 1.5 8.7 0.4 2.9 2 1 1 3 3 3 0 Basic region leucine zipper Prefoldin_2 PF01920.15 CBZ26326.1 - 9.9 5.9 9.6 3 7.6 1.4 2.5 1 1 2 3 3 3 0 Prefoldin subunit Cyt-b5 PF00173.23 CBZ26327.1 - 1.7e-16 59.7 0.0 1.9e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MAGP PF05507.6 CBZ26328.1 - 0.1 12.4 5.1 5.8 6.7 0.0 3.4 3 0 0 3 3 3 0 Microfibril-associated glycoprotein (MAGP) Abhydrolase_6 PF12697.2 CBZ26329.1 - 9e-12 45.3 9.8 1.8e-07 31.3 3.3 3.5 2 2 1 3 3 3 2 Alpha/beta hydrolase family End_tail_spike PF12219.3 CBZ26329.1 - 0.072 12.9 0.2 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase WD40 PF00400.27 CBZ26330.1 - 1.8e-18 65.6 3.6 8.9e-05 22.2 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Flavodoxin_1 PF00258.20 CBZ26331.1 - 3.7e-26 91.8 0.0 1.1e-21 77.3 0.0 4.6 5 1 0 5 5 5 2 Flavodoxin FAD_binding_1 PF00667.15 CBZ26331.1 - 3e-19 69.3 0.0 6e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CBZ26331.1 - 8.1e-12 45.6 0.0 3.5e-11 43.6 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain RabGAP-TBC PF00566.13 CBZ26332.1 - 3.4e-05 23.4 0.1 0.0001 21.8 0.1 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PIG-P PF08510.7 CBZ26334.1 - 3.3e-32 110.7 1.2 3.9e-32 110.5 0.8 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.7 CBZ26334.1 - 2.9 8.2 9.7 10 6.4 6.7 1.9 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DNA_ligase_A_N PF04675.9 CBZ26335.1 - 0.083 12.7 0.5 5.8 6.6 0.0 3.1 3 0 0 3 3 3 0 DNA ligase N terminus FAST_1 PF06743.10 CBZ26336.1 - 0.00021 20.9 3.6 5 6.9 0.1 6.0 5 2 1 6 6 6 3 FAST kinase-like protein, subdomain 1 DUF1749 PF08538.5 CBZ26337.1 - 3e-13 49.3 0.0 4.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 CBZ26337.1 - 3.3e-08 33.6 2.7 5.3e-08 33.0 1.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_26 PF13659.1 CBZ26339.1 - 4.2e-06 26.7 0.5 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Spermine_synth PF01564.12 CBZ26339.1 - 0.00056 18.9 0.0 0.00084 18.3 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_24 PF13578.1 CBZ26339.1 - 0.0012 19.6 0.4 0.0068 17.2 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_30 PF05430.6 CBZ26339.1 - 0.0096 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 CBZ26339.1 - 0.043 14.3 0.0 0.092 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ26339.1 - 0.093 12.3 0.0 0.33 10.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain PPR_2 PF13041.1 CBZ26340.1 - 3.9e-42 142.0 7.0 3.4e-16 58.9 0.4 5.1 2 1 3 5 5 5 5 PPR repeat family PPR_3 PF13812.1 CBZ26340.1 - 6e-38 125.9 3.1 1.1e-08 34.7 0.1 6.3 6 0 0 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.15 CBZ26340.1 - 4.1e-35 117.3 1.3 2.6e-06 27.0 0.0 6.2 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.2 CBZ26340.1 - 8.1e-28 95.6 0.3 5.9e-09 35.2 0.0 6.2 6 0 0 6 6 6 5 PPR repeat TPR_14 PF13428.1 CBZ26340.1 - 2.3e-05 24.6 0.1 19 6.2 0.0 5.3 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ26340.1 - 0.009 16.3 0.0 22 5.4 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat WD40 PF00400.27 CBZ26341.1 - 2.4e-50 166.6 13.6 2.3e-09 36.7 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat SRPRB PF09439.5 CBZ26342.1 - 0.012 14.8 0.1 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Miro PF08477.8 CBZ26342.1 - 0.019 15.4 0.0 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 CBZ26342.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 CBZ26342.1 - 0.041 13.2 0.0 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 Ras family MobB PF03205.9 CBZ26342.1 - 0.057 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CBZ26342.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase LRR_4 PF12799.2 CBZ26343.1 - 2.2e-36 122.8 25.6 0.00039 19.9 0.1 13.8 8 5 6 14 14 14 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ26343.1 - 1.4e-23 82.3 46.5 1.2e-05 25.0 1.7 10.0 8 3 3 11 11 11 5 Leucine rich repeat LRR_6 PF13516.1 CBZ26343.1 - 1.3e-11 43.2 36.5 0.0033 17.3 0.1 15.2 17 1 1 18 18 18 3 Leucine Rich repeat LRR_1 PF00560.28 CBZ26343.1 - 0.0058 16.4 53.7 10 6.5 0.6 15.9 17 1 1 18 18 18 4 Leucine Rich Repeat LRR_9 PF14580.1 CBZ26343.1 - 1.4 8.4 6.0 2.9 7.4 0.2 3.7 2 1 1 3 3 3 0 Leucine-rich repeat DUF2365 PF10157.4 CBZ26344.1 - 0.089 12.6 2.2 44 3.9 0.1 3.9 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2365) 2_5_RNA_ligase2 PF13563.1 CBZ26345.1 - 0.00047 19.9 0.0 0.0013 18.4 0.0 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily MtN3_slv PF03083.11 CBZ26346.1 - 5.1e-24 83.9 20.6 2.7e-14 52.7 0.8 2.6 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange MotB_plug PF13677.1 CBZ26346.1 - 0.053 12.8 2.4 0.12 11.7 1.6 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB DUF2207 PF09972.4 CBZ26346.1 - 2 6.9 6.5 18 3.7 2.6 2.2 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) LRR_4 PF12799.2 CBZ26347.1 - 2.1e-13 49.5 7.7 1.1e-05 24.8 0.2 4.6 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ26347.1 - 2.2e-11 43.3 8.1 2.7e-06 27.0 0.3 2.9 2 2 1 3 3 3 2 Leucine rich repeat LRR_9 PF14580.1 CBZ26347.1 - 2.1e-09 37.1 0.3 7.1e-07 28.9 0.2 2.5 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.28 CBZ26347.1 - 1.6e-05 24.2 8.3 16 6.0 0.1 6.6 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_7 PF13504.1 CBZ26347.1 - 0.84 10.1 20.0 23 5.7 0.0 7.1 8 0 0 8 8 8 0 Leucine rich repeat LRR_6 PF13516.1 CBZ26347.1 - 1.6 8.9 15.3 36 4.8 0.5 5.9 5 2 1 6 6 6 0 Leucine Rich repeat RNase_PH PF01138.16 CBZ26348.1 - 2.5e-14 53.7 0.2 4.5e-14 52.8 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 LRRNT PF01462.13 CBZ26348.1 - 4 7.0 0.0 4 7.0 0.0 3.3 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain Clathrin PF00637.15 CBZ26349.1 - 4e-07 29.7 0.5 4e-07 29.7 0.4 2.8 4 0 0 4 4 4 1 Region in Clathrin and VPS Vps8 PF12816.2 CBZ26349.1 - 0.00067 18.9 0.0 1.5 7.9 0.0 3.5 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 zf-RING_2 PF13639.1 CBZ26349.1 - 0.00092 18.9 0.8 0.003 17.3 0.6 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBZ26349.1 - 0.0024 17.9 0.6 0.0024 17.9 0.4 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger DUF3533 PF12051.3 CBZ26350.1 - 2.4 6.7 4.6 3.5 6.2 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) CH PF00307.26 CBZ26351.1 - 4.9e-07 29.7 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain Es2 PF09751.4 CBZ26351.1 - 0.054 12.9 0.2 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Nuclear protein Es2 IF-2B PF01008.12 CBZ26352.1 - 2.5e-70 236.6 0.6 3.1e-70 236.3 0.4 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family UPF0029 PF01205.14 CBZ26353.1 - 1.1e-26 92.6 0.0 2.4e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 2OG-FeII_Oxy_2 PF13532.1 CBZ26354.1 - 3.9e-08 33.3 0.0 2.2e-07 30.9 0.0 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBZ26354.1 - 4e-06 27.0 0.1 9.3e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily START PF01852.14 CBZ26355.1 - 4.4e-06 26.1 0.0 0.0089 15.3 0.0 2.5 2 0 0 2 2 2 2 START domain PepSY_2 PF13670.1 CBZ26355.1 - 0.077 12.9 6.0 0.21 11.4 4.2 1.8 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DnaJ PF00226.26 CBZ26356.1 - 3.1e-07 30.0 0.0 1.4e-06 27.9 0.0 2.1 2 1 0 2 2 2 1 DnaJ domain HTH_38 PF13936.1 CBZ26356.1 - 0.0051 16.3 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 Helix-turn-helix domain KorB PF08535.5 CBZ26356.1 - 0.028 14.5 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 KorB domain Tubulin PF00091.20 CBZ26358.1 - 1.5e-35 122.9 0.0 8.1e-25 87.9 0.0 2.7 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 CBZ26358.1 - 0.025 13.5 0.1 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Ribosomal_S2 PF00318.15 CBZ26360.1 - 3.9e-44 150.3 0.2 6.1e-41 139.9 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 Sulfotransfer_1 PF00685.22 CBZ26360.1 - 0.018 14.3 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain DUF3113 PF11310.3 CBZ26361.1 - 0.0072 15.9 0.3 0.57 9.9 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3113) Cep57_CLD_2 PF14197.1 CBZ26361.1 - 0.011 15.6 7.1 0.011 15.6 4.9 10.8 8 3 1 9 9 9 0 Centrosome localisation domain of PPC89 Tho2 PF11262.3 CBZ26362.1 - 5.2 6.0 6.4 0.68 8.9 0.2 2.3 2 1 1 3 3 3 0 Transcription factor/nuclear export subunit protein 2 Baculo_PEP_C PF04513.7 CBZ26362.1 - 5.9 6.7 8.2 29 4.4 2.4 3.5 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 CBZ26362.1 - 6.2 7.0 12.8 0.71 10.0 1.8 3.1 1 1 1 2 2 2 0 Syntaxin DUF1664 PF07889.7 CBZ26362.1 - 8.3 6.2 12.8 0.72 9.6 0.8 3.4 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.4 CBZ26362.1 - 9.3 6.2 16.3 3.1 7.7 0.9 3.2 1 1 2 3 3 3 0 Zinc finger-containing protein Hexapep PF00132.19 CBZ26363.1 - 5e-10 38.4 13.7 0.00036 19.9 0.1 4.5 3 1 0 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NOB1_Zn_bind PF08772.6 CBZ26365.1 - 8e-29 99.2 0.2 1.7e-28 98.2 0.1 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DZR PF12773.2 CBZ26365.1 - 0.068 12.9 0.3 0.14 12.0 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF35_N PF12172.3 CBZ26365.1 - 0.72 9.8 3.7 5.3 7.0 2.6 2.2 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) AF1Q PF15017.1 CBZ26365.1 - 3.2 7.7 10.5 19 5.2 7.3 2.2 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator CK_II_beta PF01214.13 CBZ26368.1 - 1e-74 250.0 0.0 1.3e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CENP-B_dimeris PF09026.5 CBZ26369.1 - 0.0005 20.2 2.3 0.0017 18.5 0.1 2.2 2 0 0 2 2 2 1 Centromere protein B dimerisation domain DUF4496 PF14908.1 CBZ26370.1 - 6.8e-31 107.0 0.1 8.9e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4496) Ribosomal_S2 PF00318.15 CBZ26371.1 - 3.9e-44 150.3 0.2 6.1e-41 139.9 0.1 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 Sulfotransfer_1 PF00685.22 CBZ26371.1 - 0.018 14.3 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain Porin_3 PF01459.17 CBZ26372.1 - 0.0083 15.4 0.6 0.023 13.9 0.4 1.8 1 1 0 1 1 1 1 Eukaryotic porin DUF1869 PF08956.5 CBZ26372.1 - 0.03 13.9 0.5 0.37 10.4 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1869) VHS PF00790.14 CBZ26373.1 - 2.3e-12 46.7 0.2 1.1e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 VHS domain Kinesin PF00225.18 CBZ26374.1 - 2.4e-23 82.3 9.5 1.1e-16 60.4 0.0 3.5 4 0 0 4 4 4 2 Kinesin motor domain MIF4G PF02854.14 CBZ26375.1 - 2.6e-12 46.5 1.3 4.5e-12 45.8 0.0 2.0 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.12 CBZ26375.1 - 1.6e-11 43.9 1.0 1.6e-11 43.9 0.7 1.9 2 0 0 2 2 2 1 MA3 domain VPS28 PF03997.7 CBZ26376.1 - 3.3e-40 137.7 0.3 3.9e-40 137.4 0.2 1.0 1 0 0 1 1 1 1 VPS28 protein Phage_Mu_Gam PF07352.7 CBZ26376.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Aldedh PF00171.17 CBZ26377.1 - 1.5e-129 432.3 0.8 1.7e-129 432.2 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNF2_N PF00176.18 CBZ26378.1 - 1.4e-70 237.4 0.0 2.7e-70 236.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ26378.1 - 6.2e-14 51.6 0.0 1.5e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ26378.1 - 7.4e-06 25.9 0.0 2.9e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBZ26378.1 - 5.8e-05 22.6 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec8_exocyst PF04048.9 CBZ26378.1 - 0.046 13.3 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain AAA_22 PF13401.1 CBZ26378.1 - 0.049 13.7 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Apc4_WD40 PF12894.2 CBZ26378.1 - 0.13 11.7 0.4 2.2 7.8 0.1 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PDGF_N PF04692.8 CBZ26380.1 - 0.15 12.6 0.1 0.39 11.2 0.1 1.6 1 0 0 1 1 1 0 Platelet-derived growth factor, N terminal region PQQ_3 PF13570.1 CBZ26380.1 - 0.73 10.1 4.5 0.92 9.8 0.1 3.7 4 0 0 4 4 4 0 PQQ-like domain RskA PF10099.4 CBZ26382.1 - 0.0037 17.0 0.8 0.0084 15.8 0.5 1.7 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Glyco_hydro_65m PF03632.10 CBZ26383.1 - 1.8e-68 230.9 0.0 3.6e-68 229.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 CBZ26383.1 - 2.4e-17 63.1 0.0 6.4e-17 61.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain HAD_2 PF13419.1 CBZ26383.1 - 7.5e-08 32.7 0.8 8.6e-07 29.3 0.0 2.7 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Glyco_hydro_65C PF03633.10 CBZ26383.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain WXG100 PF06013.7 CBZ26384.1 - 0.11 12.4 0.0 0.11 12.4 0.0 11.7 13 0 0 13 13 13 0 Proteins of 100 residues with WXG Adaptin_N PF01602.15 CBZ26385.1 - 1.9e-78 264.1 0.0 2.4e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CBZ26385.1 - 2.1e-06 27.9 4.8 0.00047 20.3 1.0 4.1 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.17 CBZ26385.1 - 2.7e-05 23.8 3.0 0.53 10.5 0.1 4.2 3 0 0 3 3 3 3 HEAT repeat Exo_endo_phos PF03372.18 CBZ26386.1 - 2.6e-17 63.6 0.0 2.4e-14 53.8 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBZ26386.1 - 2.4e-06 27.1 0.0 0.00091 18.8 0.0 2.6 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase HEAT PF02985.17 CBZ26387.1 - 0.00029 20.6 7.2 0.12 12.5 0.0 5.6 5 1 1 6 6 6 2 HEAT repeat HNH_2 PF13391.1 CBZ26387.1 - 0.11 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease RdRP_4 PF02123.11 CBZ26388.1 - 0.0041 15.8 4.2 0.0078 14.9 2.4 1.5 1 1 1 2 2 2 1 Viral RNA-directed RNA-polymerase TSKS PF15358.1 CBZ26388.1 - 0.0046 15.2 2.0 0.42 8.7 0.4 2.1 1 1 1 2 2 2 2 Testis-specific serine kinase substrate HTH_22 PF13309.1 CBZ26388.1 - 0.077 12.7 1.8 1.2 8.8 0.0 3.3 3 1 1 4 4 4 0 HTH domain Cnl2_NKP2 PF09447.5 CBZ26388.1 - 0.12 12.0 8.3 2.3 7.9 0.1 3.0 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Pkinase PF00069.20 CBZ26389.1 - 0.25 10.4 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain GST_C_2 PF13410.1 CBZ26391.1 - 3.1e-09 36.5 0.1 1.2e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBZ26391.1 - 0.00029 21.2 0.0 0.00073 19.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CBZ26391.1 - 0.084 12.8 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pol_alpha_B_N PF08418.5 CBZ26392.1 - 0.24 10.9 8.7 0.5 9.8 6.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.20 CBZ26394.1 - 6.9e-58 195.8 0.0 1e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26394.1 - 1e-36 126.3 0.0 1.6e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ26394.1 - 2.6e-10 39.7 0.0 5.9e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CBZ26394.1 - 9.2e-05 22.2 0.0 0.11 12.2 0.0 3.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family zf-C2H2_jaz PF12171.3 CBZ26394.1 - 0.003 17.6 0.7 0.03 14.4 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Seadorna_VP7 PF07387.6 CBZ26394.1 - 0.018 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 CBZ26394.1 - 0.042 12.8 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FYVE_2 PF02318.11 CBZ26394.1 - 0.057 13.3 4.8 0.17 11.7 3.3 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger ZZ PF00569.12 CBZ26394.1 - 0.064 12.8 6.5 0.27 10.8 4.5 2.1 1 0 0 1 1 1 0 Zinc finger, ZZ type C1_3 PF07649.7 CBZ26394.1 - 0.55 10.3 10.9 0.31 11.1 5.5 2.1 2 0 0 2 2 2 0 C1-like domain Ubie_methyltran PF01209.13 CBZ26395.1 - 1.2e-110 368.1 0.0 1.4e-110 367.9 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 CBZ26395.1 - 1.6e-15 57.3 0.0 3.2e-15 56.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ26395.1 - 1.4e-11 44.2 0.0 1.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ26395.1 - 2.4e-11 43.8 0.0 4.5e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ26395.1 - 2.9e-07 30.8 0.0 4.6e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ26395.1 - 4.7e-07 29.6 0.0 6.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CBZ26395.1 - 0.0001 21.9 0.0 0.1 12.1 0.0 2.4 2 1 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_18 PF12847.2 CBZ26395.1 - 0.0011 19.4 0.1 0.0025 18.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CBZ26395.1 - 0.14 11.3 0.8 8.1 5.5 0.1 2.2 1 1 1 2 2 2 0 O-methyltransferase Y_phosphatase PF00102.22 CBZ26397.1 - 8.4e-67 224.9 0.0 1.1e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBZ26397.1 - 0.0011 18.5 0.1 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBZ26397.1 - 0.0011 19.2 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBZ26397.1 - 0.027 14.5 0.0 0.075 13.0 0.0 1.7 1 1 0 1 1 1 0 Inositol hexakisphosphate Pyr_redox_2 PF07992.9 CBZ26398.1 - 1.2e-29 103.6 0.0 7.2e-29 101.1 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ26398.1 - 2e-10 40.9 0.0 2.9e-07 30.7 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBZ26398.1 - 2.7e-05 24.3 0.0 0.00021 21.4 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBZ26398.1 - 6.6e-05 21.9 0.0 0.045 12.5 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 CBZ26398.1 - 0.00027 20.8 0.0 0.87 9.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CBZ26398.1 - 0.0068 15.3 0.2 1 8.1 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 CBZ26398.1 - 0.03 13.2 0.9 1.8 7.3 0.0 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Pribosyltran_N PF13793.1 CBZ26399.1 - 5.2e-39 132.5 0.3 2e-38 130.6 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CBZ26399.1 - 4.3e-29 101.5 3.8 1.3e-28 100.0 0.9 2.3 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBZ26399.1 - 5.5e-13 48.7 0.2 1.7e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBZ26399.1 - 9.1e-05 21.7 0.4 0.00018 20.7 0.1 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase DUF2745 PF10922.3 CBZ26399.1 - 0.13 12.1 0.1 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2745) BCS1_N PF08740.6 CBZ26400.1 - 8.2e-39 133.1 1.2 1.2e-38 132.6 0.9 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CBZ26400.1 - 4.7e-11 43.0 0.4 4.5e-05 23.6 0.3 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ26400.1 - 9e-05 23.2 0.0 0.00029 21.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ26400.1 - 0.00036 20.2 2.1 0.0038 16.9 0.0 3.2 2 1 0 3 3 3 1 Part of AAA domain AAA_5 PF07728.9 CBZ26400.1 - 0.0013 18.4 0.1 0.0051 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBZ26400.1 - 0.0021 17.1 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CBZ26400.1 - 0.0039 17.0 0.1 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CBZ26400.1 - 0.0081 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBZ26400.1 - 0.019 13.7 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 CBZ26400.1 - 0.019 14.9 1.9 0.14 12.0 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain KaiC PF06745.8 CBZ26400.1 - 0.071 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_3 PF07726.6 CBZ26400.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 CBZ26400.1 - 0.2 11.2 1.8 4.2 6.9 0.1 2.7 3 0 0 3 3 3 0 AAA domain AIRS_C PF02769.17 CBZ26401.1 - 1.2e-14 54.6 0.0 2.3e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CBZ26401.1 - 7.7e-08 32.4 0.0 1.7e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Extensin-like_C PF06904.7 CBZ26401.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Extensin-like protein C-terminus KH_1 PF00013.24 CBZ26402.1 - 1.1e-05 24.9 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBZ26402.1 - 0.0015 18.1 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 KH domain L27_1 PF09058.5 CBZ26402.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 L27_1 Ribosomal_60s PF00428.14 CBZ26402.1 - 2.1 8.8 14.2 5.3 7.5 9.8 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein TylF PF05711.6 CBZ26403.1 - 3.9e-17 62.1 0.5 1.2e-15 57.3 0.3 2.6 1 1 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.1 CBZ26403.1 - 2e-07 31.7 0.1 2.4e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain CmcI PF04989.7 CBZ26403.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase SEP PF08059.8 CBZ26404.1 - 1.8e-07 31.3 0.0 4.1e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 SEP domain IncA PF04156.9 CBZ26404.1 - 4.6e-05 23.1 3.7 0.00013 21.6 1.4 2.1 2 0 0 2 2 2 1 IncA protein UBX PF00789.15 CBZ26404.1 - 6.7e-05 22.8 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF664 PF04978.7 CBZ26404.1 - 0.026 14.7 1.0 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF664) Spc24 PF08286.6 CBZ26404.1 - 0.05 13.2 2.3 0.097 12.3 1.6 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TMF_TATA_bd PF12325.3 CBZ26404.1 - 0.14 11.8 6.3 0.34 10.6 4.3 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fmp27_WPPW PF10359.4 CBZ26404.1 - 0.16 10.3 2.5 0.22 9.9 1.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain APG6 PF04111.7 CBZ26404.1 - 0.17 10.8 6.7 0.26 10.2 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1700 PF08006.6 CBZ26404.1 - 0.22 10.7 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF342 PF03961.8 CBZ26404.1 - 0.25 9.7 2.3 0.39 9.0 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 CBZ26404.1 - 0.66 9.6 5.8 1.2 8.7 4.0 1.3 1 0 0 1 1 1 0 Mnd1 family TPR_MLP1_2 PF07926.7 CBZ26404.1 - 0.67 9.6 13.6 0.042 13.5 5.1 2.1 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DAO PF01266.19 CBZ26406.1 - 1.1e-40 139.6 0.0 1.4e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBZ26406.1 - 0.00057 19.8 0.1 0.0014 18.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBZ26406.1 - 0.00096 19.0 0.9 0.0036 17.1 0.1 2.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CBZ26406.1 - 0.0019 17.1 0.1 0.0035 16.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 CBZ26406.1 - 0.0024 16.9 0.5 0.063 12.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.13 CBZ26406.1 - 0.011 15.7 0.1 0.036 14.0 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.12 CBZ26406.1 - 0.011 14.7 0.3 0.17 10.9 0.0 2.7 3 0 0 3 3 3 0 Thi4 family Mqo PF06039.10 CBZ26406.1 - 0.018 13.2 0.0 0.058 11.5 0.0 1.7 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.1 CBZ26406.1 - 0.025 14.6 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ26406.1 - 0.048 14.0 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApoC-I PF04691.7 CBZ26409.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) DUF1363 PF07101.6 CBZ26409.1 - 0.046 13.7 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) HlyIII PF03006.15 CBZ26410.1 - 4.6e-52 176.6 24.6 5.9e-52 176.2 17.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.6 CBZ26410.1 - 0.0062 16.4 0.8 0.033 14.0 0.1 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) NfeD PF01957.13 CBZ26410.1 - 3.6 7.7 5.1 0.59 10.2 0.1 2.2 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding HlyIII PF03006.15 CBZ26411.1 - 2.2e-50 171.1 28.0 3.1e-50 170.6 19.4 1.2 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.15 CBZ26412.1 - 3.9e-55 186.6 28.3 4.9e-55 186.3 19.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related PCIF1_WW PF12237.3 CBZ26413.1 - 1.8e-36 125.0 0.2 3.2e-23 81.8 0.1 2.3 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain AAA_33 PF13671.1 CBZ26414.1 - 3e-06 27.1 4.7 6.9e-06 26.0 0.2 2.8 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 CBZ26414.1 - 0.0021 17.3 0.0 0.52 9.4 0.0 2.6 3 1 0 3 3 3 2 Chromatin associated protein KTI12 AAA_17 PF13207.1 CBZ26414.1 - 0.024 15.4 0.0 0.062 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBZ26414.1 - 0.06 13.1 0.6 0.26 11.0 0.1 2.4 3 0 0 3 3 3 0 Part of AAA domain AAA_29 PF13555.1 CBZ26414.1 - 0.088 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBZ26414.1 - 0.64 9.9 4.9 0.43 10.5 0.2 2.8 2 2 0 2 2 2 0 AAA ATPase domain Peptidase_M24 PF00557.19 CBZ26416.1 - 3.3e-34 118.3 0.0 6e-34 117.4 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CBZ26416.1 - 6.8e-10 38.4 0.0 1.9e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain EMP24_GP25L PF01105.19 CBZ26417.1 - 1e-11 44.9 0.0 1.3e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HrpB2 PF09487.5 CBZ26418.1 - 0.0019 18.3 0.0 0.0046 17.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB2) NERD PF08378.6 CBZ26420.1 - 7.8e-27 93.8 0.3 1.4e-26 92.9 0.2 1.5 1 0 0 1 1 1 1 Nuclease-related domain tRNA-synt_1 PF00133.17 CBZ26421.1 - 1.8e-215 716.5 0.2 1.8e-215 716.5 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CBZ26421.1 - 2.6e-21 75.9 0.1 7.2e-21 74.5 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CBZ26421.1 - 2.3e-16 59.4 2.3 1.2e-05 24.1 0.5 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CBZ26421.1 - 0.0041 16.2 0.7 0.18 10.9 0.0 3.1 2 1 1 3 3 3 1 tRNA synthetases class I (C) catalytic domain SWIM PF04434.12 CBZ26422.1 - 0.22 11.0 2.8 0.49 9.9 2.0 1.6 1 0 0 1 1 1 0 SWIM zinc finger Cyclin_N PF00134.18 CBZ26423.1 - 9.4e-05 21.9 0.1 0.0012 18.4 0.0 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain DAO PF01266.19 CBZ26425.1 - 1e-19 70.6 6.0 3.4e-18 65.7 4.2 2.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBZ26425.1 - 3.5e-08 33.3 0.3 2e-07 30.9 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBZ26425.1 - 1.5e-05 24.9 0.0 0.00039 20.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ26425.1 - 2.1e-05 24.8 2.1 3.4e-05 24.1 0.8 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CBZ26425.1 - 3.5e-05 23.0 0.2 6.9e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 CBZ26425.1 - 0.00031 20.8 0.1 0.00082 19.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBZ26425.1 - 0.00097 18.0 0.5 0.0016 17.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 CBZ26425.1 - 0.0024 16.8 0.8 0.0038 16.1 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 CBZ26425.1 - 0.012 15.3 0.8 0.027 14.1 0.5 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 CBZ26425.1 - 0.024 13.7 0.5 0.047 12.7 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CBZ26425.1 - 0.029 12.8 0.5 0.044 12.2 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 CBZ26425.1 - 0.042 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NolV PF06635.7 CBZ26425.1 - 0.067 12.3 0.3 0.14 11.3 0.2 1.4 1 0 0 1 1 1 0 Nodulation protein NolV NAD_binding_10 PF13460.1 CBZ26425.1 - 0.086 12.8 0.6 0.81 9.6 0.3 2.2 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_9 PF13454.1 CBZ26425.1 - 0.09 12.5 0.3 0.25 11.1 0.2 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 CBZ26425.1 - 0.19 11.8 0.0 0.44 10.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase OB_NTP_bind PF07717.11 CBZ26426.1 - 4.1e-23 81.3 0.0 8.3e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CBZ26426.1 - 1.3e-14 53.9 0.4 2.9e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBZ26426.1 - 6.3e-12 45.1 0.0 1.4e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ26426.1 - 1.2e-10 41.1 0.0 2.3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ26426.1 - 1.1e-05 25.6 0.1 3.7e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CBZ26426.1 - 0.006 15.8 0.2 0.058 12.6 0.0 2.6 3 0 0 3 3 3 1 PhoH-like protein T2SE PF00437.15 CBZ26426.1 - 0.0096 14.8 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 CBZ26426.1 - 0.0096 15.9 0.4 0.11 12.4 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain Kringle PF00051.13 CBZ26426.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Kringle domain KaiC PF06745.8 CBZ26426.1 - 0.055 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 CBZ26426.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.10 CBZ26426.1 - 0.14 11.9 0.1 9.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PPR PF01535.15 CBZ26428.1 - 7.8 6.7 5.8 1.1 9.3 0.1 2.6 3 0 0 3 3 3 0 PPR repeat CUE PF02845.11 CBZ26429.1 - 0.00024 20.5 0.0 0.011 15.2 0.0 2.9 3 0 0 3 3 3 1 CUE domain Cullin_binding PF03556.10 CBZ26430.1 - 2.1e-20 72.9 1.5 4.2e-20 72.0 1.0 1.4 1 0 0 1 1 1 1 Cullin binding Ribosomal_S26e PF01283.14 CBZ26431.1 - 0.072 13.3 0.9 0.072 13.3 0.6 1.6 2 1 0 2 2 2 0 Ribosomal protein S26e IcmF-related PF06761.7 CBZ26432.1 - 0.1 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Intracellular multiplication and human macrophage-killing TruD PF01142.13 CBZ26434.1 - 1e-47 162.6 0.0 3.2e-40 137.9 0.0 3.8 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) RAB3GAP2_N PF14655.1 CBZ26435.1 - 4.6e-11 42.3 0.1 1.1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus MS_channel PF00924.13 CBZ26436.1 - 1.9e-18 66.5 1.7 2.3e-18 66.2 1.2 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Gcd10p PF04189.8 CBZ26437.1 - 6.9e-74 248.6 0.0 9.2e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family LRR_4 PF12799.2 CBZ26438.1 - 5.3e-08 32.3 3.0 1.5e-05 24.4 0.1 2.5 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ26438.1 - 4e-07 29.6 0.1 3.5e-05 23.4 0.0 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 CBZ26438.1 - 0.00044 19.9 0.2 0.31 11.4 0.0 3.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 CBZ26438.1 - 0.00059 19.5 1.2 0.56 10.4 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_9 PF14580.1 CBZ26438.1 - 0.0084 15.6 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 CBZ26438.1 - 0.028 14.4 0.2 8.9 6.7 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeat DUF945 PF06097.6 CBZ26440.1 - 0.2 10.3 0.2 0.31 9.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Nitroreductase PF00881.19 CBZ26442.1 - 3.3e-12 46.5 0.3 4.1e-12 46.2 0.2 1.1 1 0 0 1 1 1 1 Nitroreductase family Picorna_P3A PF06363.6 CBZ26442.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Picornaviridae P3A protein GAGA_bind PF06217.7 CBZ26443.1 - 2.5 8.0 14.7 0.1 12.5 5.1 1.9 1 1 1 2 2 2 0 GAGA binding protein-like family HMG_box_2 PF09011.5 CBZ26444.1 - 1.2e-06 28.7 2.3 0.0034 17.7 0.1 2.4 2 1 0 2 2 2 2 HMG-box domain YABBY PF04690.8 CBZ26444.1 - 0.00019 21.7 0.4 0.00022 21.5 0.3 1.1 1 0 0 1 1 1 1 YABBY protein DUF3106 PF11304.3 CBZ26444.1 - 0.006 16.9 1.3 0.01 16.2 0.5 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3106) HMG_box PF00505.14 CBZ26444.1 - 0.01 16.0 5.1 0.21 11.8 0.5 3.0 2 2 0 2 2 2 0 HMG (high mobility group) box Ribosomal_L6 PF00347.18 CBZ26444.1 - 0.029 14.8 0.1 0.043 14.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L6 AAA PF00004.24 CBZ26446.1 - 3.3e-11 43.5 0.0 0.00014 22.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ26446.1 - 5e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 CBZ26446.1 - 0.0051 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 CBZ26446.1 - 0.012 15.5 1.9 0.021 14.8 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CBZ26446.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBZ26446.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 CBZ26448.1 - 2.5e-67 226.3 0.5 3.4e-67 225.9 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ26448.1 - 1.4e-06 28.2 0.0 2.8e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 CBZ26448.1 - 8.1e-06 25.1 0.0 1.6e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CBZ26448.1 - 0.0028 18.1 0.0 0.012 16.0 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein YliH PF10799.3 CBZ26448.1 - 0.0048 16.5 0.1 0.014 15.0 0.0 1.8 1 0 0 1 1 1 1 Biofilm formation protein (YliH/bssR) Ras PF00071.17 CBZ26448.1 - 0.0068 15.8 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Ras family ATP_bind_1 PF03029.12 CBZ26448.1 - 0.0087 15.6 0.2 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein DUF910 PF06014.6 CBZ26448.1 - 0.0091 15.8 0.1 0.042 13.7 0.0 2.2 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF910) SRPRB PF09439.5 CBZ26448.1 - 0.0092 15.2 0.0 0.024 13.8 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RPAP3_C PF13877.1 CBZ26448.1 - 0.069 13.1 1.9 0.14 12.1 1.3 1.5 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Pro-rich_19 PF15455.1 CBZ26448.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Proline-rich 19 CDP-OH_P_transf PF01066.16 CBZ26450.1 - 5.4e-18 65.1 2.2 5.4e-18 65.1 1.5 3.2 2 1 1 3 3 3 1 CDP-alcohol phosphatidyltransferase HAD_2 PF13419.1 CBZ26451.1 - 3.6e-10 40.3 0.0 2e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBZ26451.1 - 0.00087 19.7 0.1 0.0013 19.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3106 PF11304.3 CBZ26452.1 - 0.53 10.7 5.7 1 9.7 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3106) Taxilin PF09728.4 CBZ26453.1 - 0.00031 19.9 51.0 0.0004 19.5 35.4 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF4061 PF13270.1 CBZ26453.1 - 0.029 14.4 6.0 0.029 14.4 4.2 3.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4061) Orexin_rec2 PF03827.8 CBZ26453.1 - 0.12 12.4 0.4 2.9 8.0 0.0 3.0 2 0 0 2 2 2 0 Orexin receptor type 2 NPV_P10 PF05531.7 CBZ26453.1 - 9.6 6.5 18.0 12 6.2 0.0 4.6 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein LmjF365940-deam PF14421.1 CBZ26454.1 - 6e-43 146.4 0.0 1.8e-22 79.6 0.0 2.3 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases zf-CCCH_2 PF14608.1 CBZ26454.1 - 0.001 18.9 0.6 0.0031 17.4 0.4 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type Terminase_GpA PF05876.7 CBZ26455.1 - 0.027 12.8 0.5 0.04 12.2 0.3 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Ead_Ea22 PF13935.1 CBZ26455.1 - 0.062 13.6 0.5 0.12 12.6 0.3 1.5 1 1 0 1 1 1 0 Ead/Ea22-like protein GDPD PF03009.12 CBZ26456.1 - 9e-25 87.6 0.2 2.1e-24 86.4 0.1 1.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.14 CBZ26456.1 - 0.0098 15.3 0.1 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF975 PF06161.6 CBZ26457.1 - 0.0097 15.6 2.0 0.0097 15.6 1.4 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF975) DUF3377 PF11857.3 CBZ26457.1 - 0.29 10.7 3.6 1.4 8.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) TMEM156 PF15106.1 CBZ26457.1 - 0.3 10.2 1.6 0.4 9.8 0.0 1.9 2 0 0 2 2 2 0 TMEM156 protein family DUF2207 PF09972.4 CBZ26457.1 - 0.78 8.2 8.0 4.5 5.7 2.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) NfeD PF01957.13 CBZ26457.1 - 0.88 9.7 8.1 8.6 6.4 0.0 2.4 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Tmemb_185A PF10269.4 CBZ26457.1 - 8.5 5.8 25.3 0.069 12.7 0.3 3.1 1 1 1 3 3 3 0 Transmembrane Fragile-X-F protein RRM_1 PF00076.17 CBZ26458.1 - 0.039 13.5 0.0 0.084 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoV PF08183.6 CBZ26459.1 - 4.5e-08 32.6 0.0 8.2e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Stage V sporulation protein family OTU PF02338.14 CBZ26462.1 - 7.1e-12 45.9 0.1 1.8e-11 44.6 0.0 1.7 2 1 0 2 2 2 1 OTU-like cysteine protease AAA_17 PF13207.1 CBZ26463.1 - 3.5e-08 34.2 0.0 0.00092 20.0 0.0 3.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CBZ26463.1 - 0.00072 19.4 8.5 0.0055 16.5 0.0 4.5 4 0 0 4 4 4 1 AAA domain YHS PF04945.8 CBZ26463.1 - 0.0008 19.2 6.8 0.12 12.2 0.2 3.8 5 0 0 5 5 5 2 YHS domain ADK PF00406.17 CBZ26463.1 - 0.002 18.0 0.2 0.012 15.4 0.0 2.5 3 0 0 3 3 3 1 Adenylate kinase AAA PF00004.24 CBZ26463.1 - 0.004 17.3 0.0 0.012 15.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CBZ26463.1 - 0.0064 16.7 0.1 0.17 12.1 0.0 3.2 2 1 0 2 2 2 1 AAA domain DUF3508 PF12018.3 CBZ26463.1 - 0.027 13.4 1.3 12 4.7 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3508) AAA_5 PF07728.9 CBZ26463.1 - 0.11 12.1 0.4 0.65 9.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Hpr_kinase_C PF07475.7 CBZ26463.1 - 0.24 10.6 0.2 3.7 6.8 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.17 CBZ26463.1 - 0.56 10.3 0.0 7.8 6.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase COG2 PF06148.6 CBZ26464.1 - 8e-43 145.5 0.1 2.3e-42 143.9 0.0 1.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 CBZ26464.1 - 1.7e-19 70.1 0.0 5.2e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) MIF4G PF02854.14 CBZ26466.1 - 3.7e-23 82.0 0.0 7.2e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain RabGAP-TBC PF00566.13 CBZ26467.1 - 9e-56 188.7 0.0 1.2e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.13 CBZ26468.1 - 2.5e-59 200.3 0.1 3.3e-59 199.9 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_hydro_39 PF01229.12 CBZ26468.1 - 0.055 11.8 0.0 0.15 10.4 0.0 1.7 1 1 1 2 2 2 0 Glycosyl hydrolases family 39 ABC1 PF03109.11 CBZ26469.1 - 3.1e-28 98.1 0.0 6.7e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 CBZ26469.1 - 1.2e-06 27.8 0.3 0.044 12.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26469.1 - 1.4e-06 27.6 0.0 0.0064 15.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBZ26469.1 - 2.2e-05 24.3 0.0 8.6e-05 22.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ26469.1 - 0.00016 21.0 0.1 0.00091 18.6 0.0 2.0 2 0 0 2 2 2 1 RIO1 family NanE PF04131.9 CBZ26469.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Apc3 PF12895.2 CBZ26470.1 - 0.0018 18.3 15.8 0.79 9.8 0.2 5.2 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBZ26470.1 - 0.002 18.3 13.2 5.6 7.3 1.7 5.2 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ26470.1 - 0.0098 15.7 14.8 6 7.0 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ26470.1 - 0.018 15.6 20.4 1.1 10.1 0.2 6.3 4 2 1 5 5 5 0 Tetratricopeptide repeat PPR_3 PF13812.1 CBZ26470.1 - 0.069 13.4 3.1 37 4.9 0.0 5.0 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR PF01535.15 CBZ26470.1 - 0.093 12.7 0.2 14 5.9 0.0 3.0 2 0 0 2 2 2 0 PPR repeat TPR_8 PF13181.1 CBZ26470.1 - 0.18 11.6 4.6 3.3 7.7 0.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ26470.1 - 1.3 9.7 24.2 4.5 8.0 0.7 5.9 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ26470.1 - 9.6 6.2 23.0 2.8 7.9 0.6 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat EF-hand_7 PF13499.1 CBZ26471.1 - 9.7e-13 48.0 0.7 5.7e-05 23.1 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ26471.1 - 2.5e-10 39.3 4.2 0.0035 17.1 0.0 4.6 3 1 2 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 CBZ26471.1 - 7.4e-10 38.3 0.8 0.00015 21.3 0.3 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ26471.1 - 1.9e-08 33.0 1.6 0.011 15.0 0.0 4.8 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 CBZ26471.1 - 3.5e-06 26.8 0.1 0.0061 16.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CBZ26471.1 - 0.009 15.3 0.4 7 6.1 0.1 3.6 3 0 0 3 3 3 1 EF hand DUF3435 PF11917.3 CBZ26471.1 - 0.06 12.0 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) ATP_bind_3 PF01171.15 CBZ26472.1 - 1.3e-17 63.8 0.0 2.2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 CBZ26472.1 - 0.079 11.4 0.0 0.17 10.3 0.0 1.5 1 1 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.14 CBZ26472.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.4 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family TF_Zn_Ribbon PF08271.7 CBZ26472.1 - 0.58 9.5 3.3 0.67 9.3 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding S1-P1_nuclease PF02265.11 CBZ26473.1 - 0.00063 19.4 0.7 0.0015 18.2 0.3 1.8 1 1 1 2 2 2 1 S1/P1 Nuclease HrpB2 PF09487.5 CBZ26473.1 - 1.6 8.9 9.0 0.7 10.0 0.1 2.9 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Fis1_TPR_C PF14853.1 CBZ26475.1 - 0.00011 21.9 0.5 0.00027 20.7 0.4 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 CBZ26475.1 - 0.0031 17.1 0.1 0.0064 16.1 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CBZ26475.1 - 0.0057 16.2 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ26475.1 - 0.11 12.5 0.1 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Ran_BP1 PF00638.13 CBZ26476.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.5 1 1 0 1 1 1 1 RanBP1 domain Kelch_4 PF13418.1 CBZ26477.1 - 6.4e-16 57.8 4.5 0.0049 16.6 0.0 6.5 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ26477.1 - 1e-15 57.2 1.2 0.0058 16.5 0.0 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 CBZ26477.1 - 6.9e-14 51.5 18.9 0.00017 21.6 0.0 7.1 6 2 1 7 7 7 4 Galactose oxidase, central domain Kelch_1 PF01344.20 CBZ26477.1 - 3.6e-12 45.6 0.0 0.00075 18.9 0.0 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 CBZ26477.1 - 1.8e-06 27.8 4.9 0.24 11.6 0.1 5.8 6 1 1 7 7 7 2 Kelch motif Kelch_2 PF07646.10 CBZ26477.1 - 2.5e-05 23.8 0.3 1.2 9.0 0.2 5.4 5 1 0 5 5 5 1 Kelch motif Suc_Fer-like PF06999.7 CBZ26478.1 - 4.2e-25 89.1 0.2 5.9e-25 88.6 0.1 1.3 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Vps54 PF07928.7 CBZ26481.1 - 5.1e-34 117.3 4.1 3.2e-31 108.2 0.2 3.6 4 0 0 4 4 4 2 Vps54-like protein GCN5L1 PF06320.8 CBZ26481.1 - 0.019 14.8 0.0 0.079 12.7 0.0 2.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) COG2 PF06148.6 CBZ26481.1 - 0.042 13.7 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Arf PF00025.16 CBZ26483.1 - 1.2e-60 203.6 0.0 1.4e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ26483.1 - 6.6e-13 48.3 0.0 7.5e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBZ26483.1 - 1.7e-12 47.9 0.0 2.3e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CBZ26483.1 - 6.9e-12 45.0 0.0 8.1e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBZ26483.1 - 3.3e-11 42.5 0.0 1.8e-08 33.4 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CBZ26483.1 - 3.6e-11 43.0 0.0 5.4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ26483.1 - 3.5e-09 36.1 0.0 4.1e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CBZ26483.1 - 1.7e-05 24.3 0.0 0.00014 21.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CBZ26483.1 - 0.0046 16.4 0.1 0.016 14.7 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 CBZ26483.1 - 0.0083 15.4 0.2 0.14 11.4 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBZ26483.1 - 0.015 15.1 0.0 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 Dynamin family ArgK PF03308.11 CBZ26483.1 - 0.015 14.0 0.1 0.18 10.5 0.1 2.2 2 1 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 CBZ26483.1 - 0.034 14.9 0.3 0.92 10.3 0.2 2.2 1 1 0 1 1 1 0 AAA domain DSBA PF01323.15 CBZ26483.1 - 0.04 13.4 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AAA_18 PF13238.1 CBZ26483.1 - 0.057 13.7 0.0 0.083 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain CdhD PF03599.11 CBZ26483.1 - 0.12 10.7 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit AAA_28 PF13521.1 CBZ26484.1 - 0.00029 20.8 0.1 0.00058 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ26484.1 - 0.087 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 CBZ26484.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Miro PF08477.8 CBZ26484.1 - 0.21 12.1 0.0 1 9.8 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Ras PF00071.17 CBZ26485.1 - 1e-46 158.2 0.3 1.4e-46 157.8 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ26485.1 - 1e-14 55.0 0.0 2.1e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ26485.1 - 1.1e-06 27.9 0.1 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBZ26485.1 - 0.00077 19.4 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBZ26485.1 - 0.0054 15.8 0.3 0.035 13.2 0.0 2.0 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 CBZ26485.1 - 0.053 12.7 0.1 8.5 5.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B DnaJ PF00226.26 CBZ26487.1 - 2.3e-28 97.7 5.6 3.6e-28 97.0 3.9 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBZ26487.1 - 8.2e-24 83.3 0.3 4e-21 74.6 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain Sugar_tr PF00083.19 CBZ26488.1 - 3.5e-106 355.4 41.8 1.3e-104 350.3 29.0 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBZ26488.1 - 2.2e-17 62.8 32.6 5.4e-16 58.2 20.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1430 PF07242.6 CBZ26488.1 - 0.45 10.6 0.0 0.45 10.6 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1430) Sugar_tr PF00083.19 CBZ26489.1 - 3.8e-106 355.3 42.2 1.4e-104 350.2 29.2 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBZ26489.1 - 9.3e-17 60.7 34.1 8.3e-16 57.6 21.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1430 PF07242.6 CBZ26489.1 - 0.45 10.6 0.0 0.45 10.6 0.0 3.3 5 1 0 5 5 5 0 Protein of unknown function (DUF1430) Sugar_tr PF00083.19 CBZ26490.1 - 5.1e-106 354.9 40.7 1.7e-104 349.9 28.2 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBZ26490.1 - 3.8e-16 58.7 35.8 8.5e-15 54.3 23.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1430 PF07242.6 CBZ26490.1 - 0.49 10.4 0.0 0.49 10.4 0.0 3.2 5 0 0 5 5 5 0 Protein of unknown function (DUF1430) S-methyl_trans PF02574.11 CBZ26491.1 - 8.4e-74 248.6 0.0 9.4e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.20 CBZ26491.1 - 0.0052 16.3 1.1 0.012 15.1 0.0 2.0 2 0 0 2 2 2 1 Kelch motif AAA_33 PF13671.1 CBZ26491.1 - 0.091 12.6 0.1 2.9 7.7 0.0 2.2 1 1 0 2 2 2 0 AAA domain FAT PF02259.18 CBZ26492.1 - 6.3e-56 189.8 0.2 1.2e-55 188.8 0.1 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CBZ26492.1 - 2.1e-53 181.1 0.1 4.2e-53 180.2 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 CBZ26492.1 - 2.8e-35 121.6 0.2 1.4e-33 116.0 0.0 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 CBZ26492.1 - 9.5e-29 99.4 0.3 4.2e-28 97.3 0.2 2.3 1 0 0 1 1 1 1 Rapamycin binding domain FATC PF02260.15 CBZ26492.1 - 2.4e-16 58.8 0.1 2.4e-16 58.8 0.1 1.9 2 0 0 2 2 2 1 FATC domain HEAT_2 PF13646.1 CBZ26492.1 - 0.00049 20.3 16.1 0.33 11.2 0.1 7.7 9 0 0 9 9 9 2 HEAT repeats HEAT_EZ PF13513.1 CBZ26492.1 - 0.84 10.2 17.2 56 4.3 0.0 8.8 10 0 0 10 10 10 0 HEAT-like repeat PEX11 PF05648.9 CBZ26493.1 - 0.004 16.4 0.0 0.0076 15.5 0.0 1.5 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HECT PF00632.20 CBZ26494.1 - 2.2e-55 188.0 0.0 3.6e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CBZ26494.1 - 4.1e-39 133.5 0.0 2.9e-17 62.9 0.0 4.3 4 1 0 4 4 4 3 SPRY domain Laminin_G_3 PF13385.1 CBZ26494.1 - 1.6e-19 70.7 0.1 4.5e-09 36.7 0.0 4.2 5 0 0 5 5 5 2 Concanavalin A-like lectin/glucanases superfamily DUF2361 PF10153.4 CBZ26494.1 - 2.6 8.2 0.1 5.6 7.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) APP_E2 PF12925.2 CBZ26494.1 - 6.1 6.3 4.3 3.3 7.2 1.1 1.9 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein Syntaxin-6_N PF09177.6 CBZ26496.1 - 0.059 13.7 0.3 0.8 10.1 0.0 2.4 2 1 1 3 3 3 0 Syntaxin 6, N-terminal CAF1 PF04857.15 CBZ26497.1 - 1.3e-39 136.1 0.1 1.8e-39 135.6 0.1 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF2962 PF11176.3 CBZ26498.1 - 3.6e-33 114.3 0.2 3.6e-33 114.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2962) RabGAP-TBC PF00566.13 CBZ26499.1 - 6e-21 74.8 0.4 9.1e-21 74.3 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Nucleoporin_FG PF13634.1 CBZ26499.1 - 0.0014 18.8 28.2 0.0026 17.9 19.5 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeat region Takusan PF04822.8 CBZ26499.1 - 0.047 13.4 0.2 4.6 7.0 0.0 3.3 3 0 0 3 3 3 0 Takusan DUF1126 PF06565.7 CBZ26500.1 - 7.2e-37 124.5 0.2 6.5e-13 47.9 0.0 3.9 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_8 PF13833.1 CBZ26500.1 - 1.1e-06 28.1 0.6 0.005 16.4 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.1 CBZ26500.1 - 0.00034 20.6 0.2 0.0034 17.4 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ26500.1 - 0.032 14.1 0.5 8.1 6.6 0.1 3.9 4 0 0 4 4 4 0 EF-hand domain EF-hand_1 PF00036.27 CBZ26500.1 - 0.095 12.0 0.6 0.45 9.9 0.1 2.4 2 0 0 2 2 2 0 EF hand MTHFR PF02219.12 CBZ26501.1 - 2.2e-94 315.7 0.0 2.6e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Ribosomal_S8e PF01201.17 CBZ26502.1 - 1.7e-35 122.0 11.1 1.4e-34 119.1 7.7 2.1 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3746 PF12562.3 CBZ26502.1 - 0.12 12.2 0.7 0.69 9.8 0.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3746) DUF4496 PF14908.1 CBZ26503.1 - 6.7e-11 42.2 0.0 2.4e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4496) MarR_2 PF12802.2 CBZ26503.1 - 0.02 14.5 0.0 11 5.7 0.0 2.9 2 0 0 2 2 2 0 MarR family TB2_DP1_HVA22 PF03134.14 CBZ26504.1 - 0.04 13.6 1.3 0.057 13.1 0.9 1.3 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Sec23_trunk PF04811.10 CBZ26505.1 - 3.6e-50 170.6 0.0 6.8e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CBZ26505.1 - 2.4e-28 97.5 0.1 5.3e-28 96.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CBZ26505.1 - 3.9e-20 72.1 1.1 3.9e-20 72.1 0.7 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CBZ26505.1 - 2.1e-13 49.5 1.3 5.3e-13 48.3 0.9 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CBZ26505.1 - 3.3e-05 23.4 0.0 0.0001 21.9 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat DUF1539 PF07560.6 CBZ26506.1 - 0.013 15.3 0.3 0.13 12.0 0.0 2.0 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) His_Phos_2 PF00328.17 CBZ26508.1 - 1.6e-25 90.2 0.3 1e-24 87.5 0.2 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) UFD1 PF03152.9 CBZ26509.1 - 6.5e-51 171.9 0.0 7.9e-51 171.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 PCI PF01399.22 CBZ26511.1 - 0.00023 21.4 0.0 0.00049 20.3 0.0 1.6 1 0 0 1 1 1 1 PCI domain SdpI PF13630.1 CBZ26513.1 - 0.011 15.4 4.4 0.011 15.4 3.0 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family MFS_1 PF07690.11 CBZ26513.1 - 0.011 14.4 5.1 0.014 14.1 3.5 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily UbiA PF01040.13 CBZ26513.1 - 0.017 14.3 8.2 0.022 13.9 5.7 1.3 1 1 0 1 1 1 0 UbiA prenyltransferase family 7TMR-DISM_7TM PF07695.6 CBZ26513.1 - 0.64 9.6 12.2 0.34 10.5 7.0 1.4 1 1 0 1 1 1 0 7TM diverse intracellular signalling 2TM PF13239.1 CBZ26513.1 - 4.5 7.4 8.0 1.1 9.3 3.4 1.7 1 1 1 2 2 2 0 2TM domain Tetraspannin PF00335.15 CBZ26513.1 - 9.6 5.4 11.9 0.97 8.6 5.0 1.7 1 1 0 1 1 1 0 Tetraspanin family DUF904 PF06005.7 CBZ26514.1 - 0.33 11.2 3.1 0.33 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Myb_DNA-binding PF00249.26 CBZ26515.1 - 1.4e-05 25.0 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain ECM1 PF05782.6 CBZ26515.1 - 0.057 12.1 1.1 0.099 11.3 0.8 1.4 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) DUF1963 PF09234.5 CBZ26515.1 - 8.8 6.4 8.7 1.1 9.4 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1963) DLH PF01738.13 CBZ26516.1 - 2.4e-23 82.6 0.0 2.8e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CBZ26516.1 - 1.8e-08 34.2 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ26516.1 - 2.3e-06 27.6 0.4 4.2e-06 26.8 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 CBZ26516.1 - 0.023 14.4 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF72 PF01904.13 CBZ26516.1 - 0.095 12.4 0.1 0.41 10.3 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF72 Cys_rich_CWC PF14375.1 CBZ26516.1 - 0.15 11.9 1.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Cysteine-rich CWC Peptidase_S15 PF02129.13 CBZ26516.1 - 0.15 11.4 0.0 4 6.7 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PCMT PF01135.14 CBZ26517.1 - 1.1e-46 159.0 0.0 1.5e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 CBZ26517.1 - 4.3e-08 33.7 0.0 7.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF4491 PF14898.1 CBZ26517.1 - 0.00019 21.5 0.1 0.095 12.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4491) Methyltransf_32 PF13679.1 CBZ26517.1 - 0.00025 20.7 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ26517.1 - 0.0019 18.2 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ26517.1 - 0.0029 17.2 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CBZ26517.1 - 0.018 15.8 0.0 0.029 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 CBZ26517.1 - 0.024 13.6 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 CBZ26517.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_23 PF13489.1 CBZ26517.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain ACBP PF00887.14 CBZ26518.1 - 3e-16 58.8 0.1 5.7e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Flavoprotein PF02441.14 CBZ26519.1 - 0.014 15.0 0.2 0.014 15.0 0.2 1.9 2 0 0 2 2 2 0 Flavoprotein HEAT_EZ PF13513.1 CBZ26519.1 - 0.039 14.4 3.6 0.039 14.4 2.5 2.1 2 0 0 2 2 2 0 HEAT-like repeat DUF4449 PF14613.1 CBZ26519.1 - 0.067 13.1 2.1 0.1 12.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) HEAT PF02985.17 CBZ26519.1 - 0.073 13.1 0.2 0.27 11.4 0.1 2.1 1 0 0 1 1 1 0 HEAT repeat SRI PF08236.6 CBZ26519.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain FAA_hydrolase_N PF09298.6 CBZ26519.1 - 0.93 9.5 5.9 1.6 8.7 1.1 2.6 1 1 2 3 3 3 0 Fumarylacetoacetase N-terminal Macoilin PF09726.4 CBZ26519.1 - 9.7 4.3 13.0 12 4.0 9.0 1.0 1 0 0 1 1 1 0 Transmembrane protein NYD-SP28_assoc PF14775.1 CBZ26521.1 - 3e-22 78.0 3.6 3e-22 78.0 2.5 3.4 2 1 1 3 3 3 1 Sperm tail C-terminal domain NYD-SP28 PF14772.1 CBZ26521.1 - 5.9e-19 68.0 3.0 5.9e-19 68.0 2.1 5.6 5 2 2 7 7 7 2 Sperm tail Ovate PF04844.8 CBZ26521.1 - 0.0038 16.9 1.3 6.8 6.5 0.0 3.8 3 1 1 4 4 4 2 Transcriptional repressor, ovate OmpH PF03938.9 CBZ26521.1 - 0.012 15.5 5.9 0.012 15.5 4.1 5.2 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) FliD_C PF07195.7 CBZ26521.1 - 1.8 7.8 27.3 0.094 11.9 2.8 3.8 4 0 0 4 4 4 0 Flagellar hook-associated protein 2 C-terminus Mito_carr PF00153.22 CBZ26523.1 - 2.5e-33 113.6 3.9 1.3e-12 47.2 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein KASH PF10541.4 CBZ26524.1 - 0.044 13.6 0.0 0.044 13.6 0.0 4.2 6 1 0 6 6 6 0 Nuclear envelope localisation domain DUF3619 PF12279.3 CBZ26524.1 - 3.6 7.6 5.9 5.7 7.0 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) Pneumo_matrix PF03393.11 CBZ26526.1 - 0.071 12.0 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 Pneumovirus matrix protein CSD PF00313.17 CBZ26526.1 - 0.14 11.9 0.0 0.45 10.3 0.0 1.8 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Metalloenzyme PF01676.13 CBZ26527.1 - 3.9e-70 236.1 0.0 4.4e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 CBZ26527.1 - 1.8e-62 210.6 0.0 2.4e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 CBZ26527.1 - 3.2e-07 30.0 0.1 9e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase FtsJ PF01728.14 CBZ26528.1 - 4e-28 98.6 0.0 9.6e-28 97.3 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Cyt-b5 PF00173.23 CBZ26529.1 - 4.1e-12 45.7 0.0 5.5e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Thioredoxin_2 PF13098.1 CBZ26529.1 - 0.079 13.1 0.1 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain bZIP_2 PF07716.10 CBZ26530.1 - 0.012 15.4 2.7 0.012 15.4 1.8 3.7 3 1 1 4 4 4 0 Basic region leucine zipper MRP PF09387.5 CBZ26530.1 - 0.022 14.4 1.2 0.027 14.2 0.9 1.3 1 1 0 1 1 1 0 Mitochondrial RNA binding protein MRP EDR1 PF14381.1 CBZ26530.1 - 0.025 14.1 1.6 0.027 14.0 1.1 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Melibiase PF02065.13 CBZ26530.1 - 0.047 12.3 0.3 0.051 12.2 0.2 1.1 1 0 0 1 1 1 0 Melibiase DUF3810 PF12725.2 CBZ26530.1 - 0.11 11.3 0.9 3 6.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Val_tRNA-synt_C PF10458.4 CBZ26530.1 - 0.14 12.2 0.1 0.14 12.2 0.1 3.8 3 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm GAS PF13851.1 CBZ26530.1 - 0.2 10.8 14.8 0.29 10.3 10.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sec66 PF09802.4 CBZ26530.1 - 0.27 10.6 5.3 0.16 11.3 1.7 1.8 1 1 1 2 2 2 0 Preprotein translocase subunit Sec66 DUF4239 PF14023.1 CBZ26530.1 - 0.37 10.1 4.0 0.45 9.8 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF972 PF06156.8 CBZ26530.1 - 0.56 10.5 13.7 1.9 8.8 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 CBZ26530.1 - 0.69 7.6 7.1 0.75 7.5 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3847 PF12958.2 CBZ26530.1 - 1.1 9.0 11.6 1 9.1 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3847) DUF812 PF05667.6 CBZ26530.1 - 1.3 7.4 15.9 0.24 9.8 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4407 PF14362.1 CBZ26530.1 - 1.3 7.8 8.5 1.7 7.5 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.6 CBZ26530.1 - 1.7 7.2 12.6 0.056 12.1 2.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Utp11 PF03998.8 CBZ26530.1 - 2 8.1 10.4 2.4 7.9 7.2 1.2 1 1 0 1 1 1 0 Utp11 protein BBP1_C PF15272.1 CBZ26530.1 - 3.3 7.2 11.2 6.4 6.2 0.1 2.1 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal TPR_MLP1_2 PF07926.7 CBZ26530.1 - 3.3 7.4 17.0 4 7.1 0.7 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ACCA PF03255.9 CBZ26530.1 - 4.9 6.6 7.6 6.1 6.3 0.6 2.3 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GrpE PF01025.14 CBZ26530.1 - 6.4 6.2 14.6 0.51 9.8 0.3 2.3 1 1 1 2 2 2 0 GrpE Ax_dynein_light PF10211.4 CBZ26530.1 - 7.6 6.3 15.7 4.8 6.9 6.3 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain Solute_trans_a PF03619.11 CBZ26531.1 - 4e-85 285.4 16.5 5.3e-85 285.0 11.4 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha AAA_16 PF13191.1 CBZ26532.1 - 1.2e-05 25.3 0.5 9.6e-05 22.4 0.1 2.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ26532.1 - 6.9e-05 23.0 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ26532.1 - 0.0023 17.6 0.7 0.11 12.2 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 CBZ26532.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.1 CBZ26532.1 - 0.048 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DNA_primase_S PF01896.14 CBZ26532.1 - 0.077 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit AAA_25 PF13481.1 CBZ26532.1 - 0.089 12.1 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBZ26532.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBZ26532.1 - 0.14 12.9 0.8 0.68 10.7 0.5 2.2 1 1 0 1 1 1 0 AAA domain Rep_fac_C PF08542.6 CBZ26533.1 - 2.7e-19 68.9 0.0 5.4e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBZ26533.1 - 1.4e-15 57.3 0.0 1.9e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBZ26533.1 - 2e-07 31.2 0.0 6.6e-07 29.6 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CBZ26533.1 - 0.00048 20.1 0.0 0.6 10.1 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain Rad17 PF03215.10 CBZ26533.1 - 0.0016 17.2 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 CBZ26533.1 - 0.0022 17.7 0.1 0.023 14.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBZ26533.1 - 0.0037 16.4 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBZ26533.1 - 0.0052 16.7 0.1 0.14 12.1 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 CBZ26533.1 - 0.0094 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ26533.1 - 0.013 14.5 0.3 0.15 11.0 0.0 2.6 3 1 1 4 4 4 0 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBZ26533.1 - 0.016 15.3 0.1 0.077 13.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CBZ26533.1 - 0.031 13.7 0.0 2.8 7.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_10 PF12846.2 CBZ26533.1 - 0.048 13.0 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain BBIP10 PF14777.1 CBZ26533.1 - 0.061 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 ORC4_C PF14629.1 CBZ26536.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Peptidase_S9_N PF02897.10 CBZ26537.1 - 4.6e-95 318.6 5.3 5.8e-95 318.2 3.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 CBZ26537.1 - 1.5e-66 223.6 0.0 2.8e-66 222.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 CBZ26537.1 - 0.0002 20.8 0.0 0.00039 19.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CBZ26537.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CBZ26537.1 - 0.014 14.9 0.2 0.028 13.9 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF4019 PF13211.1 CBZ26537.1 - 0.04 14.1 0.4 11 6.3 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) OSCP PF00213.13 CBZ26538.1 - 2.8e-06 27.3 0.3 1.7e-05 24.7 0.2 2.2 1 1 0 1 1 1 1 ATP synthase delta (OSCP) subunit Adaptin_N PF01602.15 CBZ26539.1 - 4.8e-108 361.7 4.2 6.2e-108 361.4 2.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CBZ26539.1 - 3.1e-19 69.5 0.3 8e-19 68.1 0.2 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CBZ26539.1 - 8e-14 51.6 0.0 9.6e-08 32.2 0.0 4.4 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 CBZ26539.1 - 5.7e-08 32.1 1.5 0.025 14.6 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat VHS PF00790.14 CBZ26539.1 - 0.0097 15.5 0.1 0.027 14.0 0.1 1.8 1 0 0 1 1 1 1 VHS domain CAP18_C PF12153.3 CBZ26539.1 - 0.021 14.4 1.0 0.058 13.0 0.7 1.8 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) HEAT_EZ PF13513.1 CBZ26539.1 - 0.029 14.8 0.2 2.4 8.7 0.1 4.0 2 1 0 2 2 2 0 HEAT-like repeat DUF2435 PF10363.4 CBZ26539.1 - 0.029 14.2 0.0 5.6 6.9 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) NIF PF03031.13 CBZ26540.1 - 3e-31 108.2 0.0 4.1e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AFG1_ATPase PF03969.11 CBZ26542.1 - 1.2e-54 185.5 3.7 1.4e-53 181.9 0.0 2.6 3 0 0 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.1 CBZ26542.1 - 0.074 13.0 1.7 0.58 10.1 0.2 3.0 3 1 0 3 3 3 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 CBZ26542.1 - 0.12 12.4 0.0 4.1 7.4 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF2042 PF09743.4 CBZ26543.1 - 1.7e-87 293.1 0.1 3.1e-87 292.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2042) 4HBT PF03061.17 CBZ26544.1 - 7.1e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 CBZ26544.1 - 0.00038 20.4 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.1 CBZ26544.1 - 0.0086 15.8 0.1 0.13 11.9 0.0 2.0 2 0 0 2 2 2 1 Thioesterase-like superfamily SET PF00856.23 CBZ26545.1 - 1.5e-07 31.8 0.0 3.1e-05 24.3 0.0 2.3 1 1 0 1 1 1 1 SET domain Aa_trans PF01490.13 CBZ26546.1 - 1.3e-42 145.7 32.4 1.5e-42 145.5 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2453 PF10507.4 CBZ26547.1 - 2e-42 143.4 5.0 4e-42 142.5 3.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) EF-hand_1 PF00036.27 CBZ26547.1 - 5.2e-07 28.5 0.2 0.0038 16.4 0.0 3.2 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 CBZ26547.1 - 4.3e-06 26.7 1.5 0.043 13.9 0.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CBZ26547.1 - 0.00021 20.9 0.2 0.15 12.0 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 CBZ26547.1 - 0.061 12.6 0.6 3.9 6.9 0.0 3.2 3 0 0 3 3 3 0 EF hand AA_permease_2 PF13520.1 CBZ26547.1 - 0.68 8.4 5.3 6.2 5.2 0.0 2.2 2 0 0 2 2 2 0 Amino acid permease RNA_lig_T4_1 PF09511.5 CBZ26549.1 - 2.2e-15 56.7 0.0 9.1e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 RNA ligase AAA_33 PF13671.1 CBZ26549.1 - 1.3e-13 51.0 0.1 1.3e-13 51.0 0.1 1.9 2 0 0 2 2 1 1 AAA domain 6PF2K PF01591.13 CBZ26549.1 - 2.2e-07 30.1 0.0 3.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase NACHT PF05729.7 CBZ26549.1 - 3.7e-06 26.6 0.7 1.1e-05 25.1 0.4 2.0 1 1 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 CBZ26549.1 - 1.9e-05 24.9 0.0 3.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CBZ26549.1 - 7.8e-05 22.3 0.0 0.00032 20.3 0.0 2.2 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 CBZ26549.1 - 0.00022 20.3 0.0 0.00061 18.9 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 CBZ26549.1 - 0.00036 21.3 0.0 0.00088 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CBZ26549.1 - 0.00055 19.2 0.0 0.00099 18.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 CBZ26549.1 - 0.00062 20.0 0.0 0.0019 18.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter CPT PF07931.7 CBZ26549.1 - 0.0019 17.8 0.4 0.11 12.1 0.1 2.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.1 CBZ26549.1 - 0.014 15.1 0.1 0.088 12.5 0.1 2.5 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 CBZ26549.1 - 0.015 14.7 0.6 0.044 13.1 0.2 1.9 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 CBZ26549.1 - 0.022 14.8 0.0 0.09 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain tRNA_lig_CPD PF08302.6 CBZ26549.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain AAA_5 PF07728.9 CBZ26549.1 - 0.037 13.7 0.0 0.086 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CBZ26549.1 - 0.039 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CBZ26549.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase TIP49 PF06068.8 CBZ26549.1 - 0.15 10.7 0.0 0.25 10.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Ank_5 PF13857.1 CBZ26550.1 - 0.088 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) EVE PF01878.13 CBZ26551.1 - 4e-53 179.2 0.2 4.6e-53 179.1 0.2 1.0 1 0 0 1 1 1 1 EVE domain Phytoreo_S7 PF07236.6 CBZ26551.1 - 0.015 13.6 0.0 0.018 13.4 0.0 1.0 1 0 0 1 1 1 0 Phytoreovirus S7 protein UPF0236 PF06782.6 CBZ26551.1 - 0.049 12.0 0.0 0.071 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) Bromodomain PF00439.20 CBZ26552.1 - 2.7e-15 56.0 0.0 4.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Nucleoporin_N PF08801.6 CBZ26553.1 - 1e-43 149.7 0.0 1.6e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.9 CBZ26553.1 - 4.9e-07 28.6 4.0 5.2e-06 25.2 2.8 2.1 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal LRR_4 PF12799.2 CBZ26554.1 - 1.1e-05 24.9 0.1 0.00092 18.7 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ26554.1 - 0.0015 18.2 0.3 0.0053 16.4 0.2 2.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 CBZ26554.1 - 0.29 11.3 7.0 14 6.2 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat Cpn60_TCP1 PF00118.19 CBZ26555.1 - 5.5e-138 460.6 7.6 6.2e-138 460.4 5.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L1 PF00687.16 CBZ26556.1 - 6.6e-22 77.9 0.0 8.1e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3633 PF12315.3 CBZ26556.1 - 0.046 13.0 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) zf-C2H2_6 PF13912.1 CBZ26557.1 - 8.7e-05 22.2 8.7 0.00065 19.5 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CBZ26557.1 - 0.0058 16.8 7.3 0.027 14.7 0.5 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CBZ26557.1 - 0.0075 16.5 10.0 0.083 13.2 1.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 CBZ26557.1 - 0.024 14.8 5.8 1.4 9.2 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBZ26557.1 - 0.14 12.2 0.8 6.9 6.8 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CBZ26557.1 - 0.23 11.6 4.5 6.7 6.9 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.7 CBZ26557.1 - 0.46 8.9 0.5 12 4.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.1 CBZ26557.1 - 1.2 9.5 12.4 4.2 7.8 0.4 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Thioredoxin PF00085.15 CBZ26559.1 - 8e-63 208.6 0.3 1.5e-31 108.1 0.0 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CBZ26559.1 - 5.9e-28 97.9 0.0 7.3e-15 55.2 0.0 3.9 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBZ26559.1 - 4.6e-17 62.2 1.9 2.7e-07 30.7 0.1 4.1 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBZ26559.1 - 9.4e-14 51.2 0.1 8.2e-07 28.9 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 CBZ26559.1 - 2.1e-12 47.0 0.6 0.0041 17.1 0.0 4.7 3 2 2 5 5 5 3 Thioredoxin-like AhpC-TSA PF00578.16 CBZ26559.1 - 1.2e-09 37.9 0.9 0.0003 20.4 0.0 3.2 3 1 0 3 3 3 2 AhpC/TSA family Thioredoxin_9 PF14595.1 CBZ26559.1 - 1.9e-05 24.2 0.0 0.027 14.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 CBZ26559.1 - 4.6e-05 23.0 1.1 0.018 14.6 0.0 3.0 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 CBZ26559.1 - 0.00031 20.4 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_4 PF13462.1 CBZ26559.1 - 0.00071 19.6 0.2 8.9 6.2 0.0 4.5 4 1 1 5 5 5 1 Thioredoxin HyaE PF07449.6 CBZ26559.1 - 0.048 13.5 0.0 0.31 10.9 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Calsequestrin PF01216.12 CBZ26559.1 - 0.072 11.8 0.4 0.12 11.1 0.1 1.6 2 0 0 2 2 2 0 Calsequestrin FA_desaturase PF00487.19 CBZ26560.1 - 1.4e-33 116.4 11.6 2.2e-33 115.8 8.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CBZ26560.1 - 7.1e-11 41.7 0.0 1.6e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Methyltransf_23 PF13489.1 CBZ26562.1 - 0.0081 15.8 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF4080 PF13311.1 CBZ26562.1 - 0.085 12.8 0.4 2.9 7.8 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4080) eIF-3c_N PF05470.7 CBZ26563.1 - 1.8e-20 72.6 1.5 7.4e-16 57.3 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CBZ26563.1 - 0.013 15.7 0.1 0.065 13.5 0.0 2.2 2 0 0 2 2 2 0 PCI domain RRM_1 PF00076.17 CBZ26564.1 - 0.00013 21.5 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ26564.1 - 0.029 14.3 0.0 0.085 12.8 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HMA PF00403.21 CBZ26564.1 - 0.049 13.7 0.6 0.19 11.9 0.0 2.1 2 1 1 3 3 3 0 Heavy-metal-associated domain Limkain-b1 PF11608.3 CBZ26564.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Arg_repressor_C PF02863.13 CBZ26564.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain MOZ_SAS PF01853.13 CBZ26565.1 - 1.1e-45 155.1 0.0 1.5e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.1 CBZ26565.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBZ26565.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C4_ClpX PF06689.8 CBZ26565.1 - 0.041 13.3 0.1 0.082 12.4 0.1 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger FR47 PF08445.5 CBZ26565.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein zf-C2H2 PF00096.21 CBZ26565.1 - 0.28 11.6 3.2 0.6 10.5 2.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBZ26565.1 - 3.4 8.2 8.1 0.78 10.2 2.6 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger PSP1 PF04468.7 CBZ26567.1 - 3.4e-30 103.8 0.1 5.6e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region RNA_pol_Rpb2_6 PF00562.23 CBZ26568.1 - 4.5e-114 381.1 0.0 6.5e-114 380.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBZ26568.1 - 1.2e-45 154.9 1.4 1.8e-45 154.3 1.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 CBZ26568.1 - 1.6e-28 98.7 0.1 3.9e-28 97.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 CBZ26568.1 - 2e-20 73.0 0.1 4e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 CBZ26568.1 - 2.3e-19 68.9 1.2 2.3e-19 68.9 0.8 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CBZ26568.1 - 5.1e-19 67.8 0.0 1e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CBZ26568.1 - 8.3e-11 41.6 0.2 2.1e-10 40.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Chlorophyllase PF07224.6 CBZ26568.1 - 0.084 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase WD40 PF00400.27 CBZ26569.1 - 2.9e-18 64.9 14.9 1.3e-07 31.2 0.6 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat PQQ_2 PF13360.1 CBZ26569.1 - 0.01 15.3 0.1 1.1 8.6 0.0 2.6 1 1 1 2 2 2 0 PQQ-like domain Gmad1 PF10647.4 CBZ26569.1 - 0.024 14.0 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 CBZ26569.1 - 0.049 11.7 3.0 0.43 8.6 2.1 2.1 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Hira PF07569.6 CBZ26569.1 - 0.072 12.2 1.6 4.9 6.3 0.2 2.9 2 2 0 2 2 2 0 TUP1-like enhancer of split DOT1 PF08123.8 CBZ26570.1 - 6.1e-20 71.4 0.0 8e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 CBZ26570.1 - 6.2e-07 29.9 0.0 1.3e-06 29.0 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ26570.1 - 4.4e-06 26.7 0.0 6.1e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ26570.1 - 2.7e-05 24.4 0.0 4.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ26570.1 - 2.7e-05 23.8 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ26570.1 - 0.0011 19.3 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ26570.1 - 0.0035 17.0 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBZ26570.1 - 0.014 14.4 0.0 0.02 14.0 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CBZ26570.1 - 0.044 14.2 0.0 0.075 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 CBZ26570.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.8 CBZ26570.1 - 0.097 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PHO4 PF01384.15 CBZ26571.1 - 8.1e-99 330.3 16.3 1.4e-98 329.5 11.3 1.4 1 1 0 1 1 1 1 Phosphate transporter family DUF2986 PF11661.3 CBZ26572.1 - 0.086 13.1 0.3 0.23 11.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) ASF1_hist_chap PF04729.8 CBZ26573.1 - 1.5e-51 174.0 0.0 1.6e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone BRCA-2_OB1 PF09103.5 CBZ26574.1 - 3e-34 117.2 0.0 5.2e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.13 CBZ26574.1 - 5.6e-08 31.9 0.1 5.2e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 BRCA2 repeat zf-RanBP PF00641.13 CBZ26574.1 - 0.026 13.6 2.6 0.067 12.3 1.8 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others 7tm_7 PF08395.7 CBZ26575.1 - 0.0046 16.0 0.2 0.0054 15.7 0.1 1.1 1 0 0 1 1 1 1 7tm Chemosensory receptor BK_channel_a PF03493.13 CBZ26577.1 - 7.4e-24 83.6 0.0 1.5e-22 79.4 0.0 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 CBZ26577.1 - 4e-12 45.6 6.1 4e-12 45.6 4.2 2.5 2 1 0 2 2 2 1 Ion channel PGK PF00162.14 CBZ26578.1 - 1.7e-151 504.2 0.0 1.9e-151 503.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PGK PF00162.14 CBZ26579.1 - 1e-151 504.9 0.0 1.2e-151 504.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase NB-ARC PF00931.17 CBZ26580.1 - 6.7e-06 25.1 0.0 0.0076 15.1 0.0 2.2 1 1 1 2 2 2 2 NB-ARC domain AAA_16 PF13191.1 CBZ26580.1 - 5.8e-05 23.1 0.0 0.00018 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 CBZ26580.1 - 0.023 14.3 0.0 0.14 11.8 0.0 2.1 1 1 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 CBZ26580.1 - 0.028 14.3 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CBZ26580.1 - 0.031 14.4 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CBZ26580.1 - 0.039 13.1 0.0 0.083 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CBZ26580.1 - 0.041 13.5 0.0 0.44 10.1 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 CBZ26580.1 - 0.091 12.9 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA helicase MORN PF02493.15 CBZ26581.1 - 2e-14 52.3 9.8 1.4e-06 27.6 0.0 7.6 7 1 0 7 7 7 5 MORN repeat DUF1736 PF08409.6 CBZ26583.1 - 1.1e-22 79.4 1.9 1.7e-22 78.8 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) TPR_11 PF13414.1 CBZ26583.1 - 0.1 12.2 2.2 2 8.1 0.0 3.4 2 1 1 3 3 3 0 TPR repeat O-antigen_lig PF13425.1 CBZ26583.1 - 2.5 8.0 19.4 8.2 6.4 0.6 3.3 2 1 0 2 2 2 0 O-antigen ligase like membrane protein Atg14 PF10186.4 CBZ26584.1 - 0.001 18.0 8.1 0.0017 17.3 5.6 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 CBZ26584.1 - 0.0036 15.8 5.0 0.0054 15.2 3.4 1.3 1 0 0 1 1 1 1 AAA domain DUF812 PF05667.6 CBZ26584.1 - 0.044 12.3 12.0 0.069 11.6 8.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Phage_GP20 PF06810.6 CBZ26584.1 - 0.12 11.8 6.0 0.22 10.9 4.1 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 CBZ26584.1 - 0.82 9.2 27.5 1.6 8.2 0.4 3.1 2 1 0 2 2 2 0 IncA protein Ada3 PF10198.4 CBZ26584.1 - 0.83 9.4 7.9 0.29 10.9 3.2 2.0 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 Reo_sigmaC PF04582.7 CBZ26584.1 - 1.3 8.0 14.3 2.2 7.3 2.7 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CBZ26584.1 - 3.5 7.4 22.8 2.5 7.9 6.0 3.4 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3138 PF11336.3 CBZ26584.1 - 4.3 5.3 7.6 2.2 6.3 3.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) TMF_TATA_bd PF12325.3 CBZ26584.1 - 4.7 6.9 19.7 0.17 11.5 5.1 3.3 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 CBZ26584.1 - 5.2 6.8 18.9 0.21 11.3 6.9 2.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein LRR_6 PF13516.1 CBZ26585.1 - 0.0024 17.7 0.0 5.6 7.3 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeat PHY PF00360.15 CBZ26585.1 - 0.033 13.3 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 Phytochrome region Cas_Csd1 PF09709.5 CBZ26588.1 - 0.064 11.5 0.0 0.099 10.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) Kelch_1 PF01344.20 CBZ26589.1 - 2.3e-25 87.8 8.2 2.3e-07 30.2 0.0 5.8 5 1 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 CBZ26589.1 - 2.4e-24 84.4 9.8 2.5e-06 27.4 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.1 CBZ26589.1 - 3.8e-23 81.0 17.6 8.5e-07 28.9 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ26589.1 - 4.7e-21 74.3 17.0 3.3e-06 26.9 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.1 CBZ26589.1 - 1.2e-19 69.8 9.9 1.9e-06 27.5 0.0 5.9 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 CBZ26589.1 - 1.4e-11 43.7 22.1 0.0044 16.7 0.1 6.8 7 1 0 7 7 7 4 Kelch motif DUF4516 PF14990.1 CBZ26591.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) BNR_assoc_N PF14873.1 CBZ26592.1 - 0.041 13.6 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase RseC_MucC PF04246.7 CBZ26592.1 - 0.046 13.3 0.0 2.8 7.5 0.0 2.6 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DS PF01916.12 CBZ26593.1 - 1.2e-76 257.6 0.0 1.6e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Peptidase_S49_N PF08496.5 CBZ26593.1 - 0.02 14.6 0.4 0.68 9.7 0.2 2.1 1 1 1 2 2 2 0 Peptidase family S49 N-terminal AAA_5 PF07728.9 CBZ26594.1 - 6.7e-124 408.1 0.0 3.4e-23 81.8 0.0 8.7 7 1 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBZ26594.1 - 1.2e-25 89.6 0.0 0.0032 17.0 0.0 8.3 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ26594.1 - 7.6e-23 81.0 0.1 0.0018 18.4 0.0 8.1 7 0 0 7 7 7 6 AAA domain AAA PF00004.24 CBZ26594.1 - 5.7e-21 75.1 0.3 0.00083 19.5 0.0 7.4 6 1 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CBZ26594.1 - 5.1e-17 61.9 0.0 0.00021 21.1 0.0 6.7 7 0 0 7 7 5 3 AAA domain Sigma54_activ_2 PF14532.1 CBZ26594.1 - 1.1e-16 61.1 1.8 0.0001 22.3 0.0 7.0 7 0 0 7 7 6 3 Sigma-54 interaction domain Sigma54_activat PF00158.21 CBZ26594.1 - 1.5e-16 60.3 0.2 0.0088 15.5 0.0 6.5 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_17 PF13207.1 CBZ26594.1 - 3.5e-14 53.6 4.9 0.059 14.1 0.0 8.0 8 0 0 8 8 6 3 AAA domain AAA_16 PF13191.1 CBZ26594.1 - 1.2e-13 51.4 40.0 0.00052 20.0 0.0 11.5 12 1 0 12 12 11 4 AAA ATPase domain AAA_19 PF13245.1 CBZ26594.1 - 3.6e-11 42.6 1.9 1.5 8.6 0.0 7.3 6 0 0 6 6 6 3 Part of AAA domain AAA_29 PF13555.1 CBZ26594.1 - 1.3e-10 40.6 2.0 2.3 7.8 0.0 6.7 6 0 0 6 6 6 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 CBZ26594.1 - 4.1e-10 39.3 0.5 0.087 12.2 0.0 4.5 5 0 0 5 5 3 3 IstB-like ATP binding protein ABC_tran PF00005.22 CBZ26594.1 - 7e-10 39.3 13.3 0.23 11.7 0.0 7.3 8 0 0 8 8 6 4 ABC transporter T2SE PF00437.15 CBZ26594.1 - 9e-10 37.9 2.0 0.046 12.6 0.0 6.2 6 0 0 6 6 6 2 Type II/IV secretion system protein UPF0079 PF02367.12 CBZ26594.1 - 8.9e-09 35.0 4.4 0.071 12.7 0.0 6.3 6 0 0 6 6 6 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 CBZ26594.1 - 9.9e-09 34.4 3.0 0.13 11.1 0.0 5.3 6 0 0 6 6 5 2 Protein of unknown function (DUF815) AAA_18 PF13238.1 CBZ26594.1 - 1.5e-08 34.9 6.3 0.17 12.1 0.0 7.3 7 0 0 7 7 7 2 AAA domain DUF258 PF03193.11 CBZ26594.1 - 1.7e-08 33.7 1.4 0.41 9.8 0.0 5.4 5 0 0 5 5 5 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CBZ26594.1 - 1.6e-07 31.4 0.6 0.39 10.9 0.0 6.2 7 0 0 7 7 6 1 RNA helicase NACHT PF05729.7 CBZ26594.1 - 2.3e-05 24.1 4.0 0.96 9.0 0.0 5.9 6 0 0 6 6 6 1 NACHT domain RuvB_N PF05496.7 CBZ26594.1 - 5.4e-05 22.3 0.6 0.67 8.9 0.0 4.8 5 0 0 5 5 5 1 Holliday junction DNA helicase ruvB N-terminus Miro PF08477.8 CBZ26594.1 - 0.0002 21.8 0.2 7.3 7.1 0.0 4.6 4 0 0 4 4 4 0 Miro-like protein NTPase_1 PF03266.10 CBZ26594.1 - 0.0018 17.9 2.2 1.7 8.3 0.0 4.2 5 0 0 5 5 4 1 NTPase Rad17 PF03215.10 CBZ26594.1 - 0.0059 15.3 2.3 15 4.1 0.0 4.7 6 0 0 6 6 6 0 Rad17 cell cycle checkpoint protein ArgK PF03308.11 CBZ26594.1 - 0.0087 14.8 1.9 1.1 8.0 0.1 3.4 3 0 0 3 3 3 1 ArgK protein KaiC PF06745.8 CBZ26594.1 - 0.0098 15.0 0.2 20 4.2 0.0 4.5 5 0 0 5 5 5 0 KaiC PduV-EutP PF10662.4 CBZ26594.1 - 0.032 13.7 0.4 41 3.6 0.0 4.6 6 0 0 6 6 5 0 Ethanolamine utilisation - propanediol utilisation TIP49 PF06068.8 CBZ26594.1 - 0.036 12.7 0.2 7.2 5.2 0.0 3.8 4 0 0 4 4 4 0 TIP49 C-terminus DNA_pol3_delta2 PF13177.1 CBZ26594.1 - 0.058 13.0 0.0 16 5.1 0.0 3.7 3 0 0 3 3 3 0 DNA polymerase III, delta subunit PhoH PF02562.11 CBZ26594.1 - 0.12 11.6 7.6 5.5 6.1 0.0 4.5 5 0 0 5 5 4 0 PhoH-like protein AAA_6 PF12774.2 CBZ26594.1 - 0.17 11.3 0.0 62 3.0 0.0 3.9 5 0 0 5 5 4 0 Hydrolytic ATP binding site of dynein motor region D1 MMR_HSR1 PF01926.18 CBZ26594.1 - 0.61 10.0 0.0 1.4e+02 2.4 0.0 3.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_21 PF13304.1 CBZ26594.1 - 0.74 9.7 0.1 21 4.9 0.0 3.2 4 0 0 4 4 3 0 AAA domain Enkurin PF13864.1 CBZ26596.1 - 4.8e-26 90.8 4.9 7.8e-26 90.1 3.4 1.3 1 0 0 1 1 1 1 Calmodulin-binding BCDHK_Adom3 PF10436.4 CBZ26597.1 - 2.6e-34 118.1 0.1 4.2e-34 117.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CBZ26597.1 - 6.8e-15 54.7 0.0 6.3e-14 51.6 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBZ26597.1 - 4e-05 23.2 0.0 7.9e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ZZ PF00569.12 CBZ26598.1 - 9.4e-07 28.2 9.3 9.4e-07 28.2 6.4 2.8 2 0 0 2 2 2 1 Zinc finger, ZZ type LRR_6 PF13516.1 CBZ26599.1 - 5e-08 32.2 0.3 0.12 12.5 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 CBZ26599.1 - 0.00068 19.4 1.0 7.8 7.1 0.0 5.0 5 0 0 5 5 5 1 Leucine rich repeat LRR_1 PF00560.28 CBZ26599.1 - 0.00099 18.8 0.4 47 4.5 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.2 CBZ26599.1 - 0.011 15.3 0.6 9.2 6.0 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 CBZ26601.1 - 6.7e-19 67.0 13.5 2.2e-07 30.3 1.9 4.7 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ26601.1 - 2.2e-11 43.3 18.9 6.7e-05 22.5 0.2 4.2 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBZ26601.1 - 3.6e-10 38.4 13.7 0.48 10.6 0.0 8.8 8 1 1 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.1 CBZ26601.1 - 2.8e-08 32.9 11.5 0.37 11.0 0.1 7.5 6 1 1 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 CBZ26601.1 - 1.4e-07 30.5 22.8 0.032 14.4 0.2 7.9 8 0 0 8 8 8 3 Leucine rich repeat Herpes_LP PF03363.8 CBZ26603.1 - 0.012 15.2 0.2 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus leader protein Acetyltransf_13 PF13880.1 CBZ26605.1 - 2.9e-22 78.1 0.1 6.7e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_1 PF00583.19 CBZ26605.1 - 0.087 12.8 0.4 3.2 7.8 0.0 2.8 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family MFS_1 PF07690.11 CBZ26606.1 - 4.5e-21 74.9 31.2 1.2e-14 53.7 6.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ26606.1 - 4.3e-06 25.5 15.4 4.3e-06 25.5 10.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter DUF2946 PF11162.3 CBZ26608.1 - 2.6e-17 63.1 1.4 3.6e-17 62.6 0.0 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF2946) Vpu PF00558.14 CBZ26608.1 - 0.0041 16.6 0.4 0.011 15.3 0.3 1.6 1 0 0 1 1 1 1 Vpu protein DUF4381 PF14316.1 CBZ26608.1 - 0.0074 16.3 0.0 0.057 13.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) Shisa PF13908.1 CBZ26608.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 CBZ26608.1 - 0.016 15.5 0.2 0.058 13.8 0.1 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF4307 PF14155.1 CBZ26608.1 - 0.022 14.5 0.2 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) NVEALA PF14055.1 CBZ26608.1 - 0.022 14.4 0.9 0.058 13.1 0.0 2.2 2 0 0 2 2 2 0 NVEALA protein DUF3481 PF11980.3 CBZ26608.1 - 0.023 14.5 0.4 0.075 12.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) DUF4526 PF15029.1 CBZ26608.1 - 0.033 13.7 0.1 0.053 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) FAM163 PF15069.1 CBZ26608.1 - 0.048 14.2 0.0 0.084 13.4 0.0 1.4 1 0 0 1 1 1 0 FAM163 family TMEM154 PF15102.1 CBZ26608.1 - 0.06 13.0 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Chordopox_A13L PF05961.6 CBZ26608.1 - 0.066 13.1 0.3 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF4366 PF14283.1 CBZ26608.1 - 0.16 11.3 0.4 5.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) cobW PF02492.14 CBZ26608.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Metallophos PF00149.23 CBZ26609.1 - 7.4e-05 22.2 0.1 0.0035 16.7 0.0 2.5 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos PF00149.23 CBZ26610.1 - 0.0018 17.7 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NUDIX PF00293.23 CBZ26611.1 - 3.3e-11 42.9 0.0 1.7e-07 30.9 0.0 3.1 2 1 0 2 2 2 2 NUDIX domain Rad1 PF02144.11 CBZ26612.1 - 8.1e-07 28.0 0.0 0.00061 18.6 0.0 2.1 2 0 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 DUF3482 PF11981.3 CBZ26613.1 - 0.024 13.8 0.2 0.024 13.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Methyltransf_8 PF05148.10 CBZ26615.1 - 4.8e-53 180.0 0.0 6.4e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CBZ26615.1 - 1.1e-07 32.1 0.1 4.2e-07 30.3 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ26615.1 - 0.00042 20.0 0.0 0.0013 18.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ26615.1 - 0.0027 16.8 0.1 0.014 14.5 0.0 2.1 1 1 2 3 3 3 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 CBZ26615.1 - 0.014 14.6 0.0 0.038 13.1 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB B12-binding PF02310.14 CBZ26615.1 - 0.12 12.2 0.1 0.5 10.2 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain Methyltransf_31 PF13847.1 CBZ26615.1 - 0.15 11.6 0.1 7 6.2 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain DAO PF01266.19 CBZ26616.1 - 2.4e-18 66.1 0.0 4.7e-10 38.9 0.1 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBZ26616.1 - 4.8e-07 28.9 0.6 8.3e-07 28.1 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 CBZ26616.1 - 3.3e-06 26.2 0.5 1.4e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 CBZ26616.1 - 5.3e-06 25.7 0.6 9.6e-06 24.9 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBZ26616.1 - 0.00011 22.1 0.4 0.00029 20.7 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBZ26616.1 - 0.0002 21.2 0.0 0.00039 20.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBZ26616.1 - 0.00027 19.5 0.2 0.0004 18.9 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 CBZ26616.1 - 0.018 13.9 0.4 0.032 13.1 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CBZ26616.1 - 0.055 13.5 0.3 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ26616.1 - 0.06 13.7 0.3 0.06 13.7 0.2 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CBZ26616.1 - 0.15 11.7 0.3 0.35 10.5 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AIG2_2 PF13772.1 CBZ26617.1 - 3.7e-09 36.5 0.1 4.3e-08 33.1 0.0 2.6 3 0 0 3 3 3 1 AIG2-like family AIG2 PF06094.7 CBZ26617.1 - 1.8e-05 25.1 0.1 0.00065 20.1 0.0 2.8 2 1 0 2 2 2 1 AIG2-like family DUF2618 PF10940.3 CBZ26618.1 - 0.046 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) TM231 PF10149.4 CBZ26619.1 - 1.2e-10 40.8 3.3 6.8e-06 25.2 0.0 2.2 2 0 0 2 2 2 2 Transmembrane protein 231 EF-hand_1 PF00036.27 CBZ26619.1 - 0.071 12.4 0.3 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 EF hand Tubulin PF00091.20 CBZ26620.1 - 4.4e-74 248.9 0.0 5.8e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.1 CBZ26620.1 - 0.0074 15.2 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin like PPR_2 PF13041.1 CBZ26621.1 - 1.5e-12 47.2 0.5 0.0004 20.2 0.0 3.9 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.15 CBZ26621.1 - 4e-09 35.8 0.9 0.022 14.7 0.0 4.2 4 0 0 4 4 4 3 PPR repeat PPR_3 PF13812.1 CBZ26621.1 - 1.1e-07 31.5 3.2 9.3e-05 22.4 0.1 4.5 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 CBZ26621.1 - 0.014 14.8 0.0 0.42 10.1 0.0 2.9 2 0 0 2 2 2 0 PPR repeat DUF4567 PF15131.1 CBZ26621.1 - 0.085 13.0 0.1 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) A2L_zn_ribbon PF08792.5 CBZ26622.1 - 0.005 16.2 0.3 0.0088 15.4 0.2 1.3 1 0 0 1 1 1 1 A2L zinc ribbon domain GFA PF04828.9 CBZ26622.1 - 0.016 15.1 0.4 0.15 12.0 0.0 1.9 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DNA_RNApol_7kD PF03604.8 CBZ26622.1 - 0.024 14.0 1.7 0.044 13.2 1.1 1.5 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit PhnA_Zn_Ribbon PF08274.7 CBZ26622.1 - 0.042 13.6 1.1 5 6.9 0.0 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF2296 PF10058.4 CBZ26622.1 - 0.043 13.5 0.0 7.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C3HC4_3 PF13920.1 CBZ26622.1 - 0.094 12.4 0.4 0.15 11.7 0.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2318 PF10080.4 CBZ26622.1 - 0.095 12.4 0.1 0.099 12.4 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DZR PF12773.2 CBZ26622.1 - 0.12 12.2 0.2 0.18 11.6 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 CBZ26622.1 - 0.16 11.3 2.2 3.7 6.9 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding zf-RING_5 PF14634.1 CBZ26622.1 - 0.2 11.3 1.1 0.33 10.7 0.8 1.3 1 0 0 1 1 1 0 zinc-RING finger domain Nudix_N_2 PF14803.1 CBZ26622.1 - 1.5 8.5 5.8 16 5.2 4.0 2.2 1 1 0 1 1 1 0 Nudix N-terminal CTP_transf_2 PF01467.21 CBZ26623.1 - 9.2e-05 22.5 0.0 0.00052 20.0 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase CinA PF02464.12 CBZ26623.1 - 0.078 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Competence-damaged protein DUF4404 PF14357.1 CBZ26624.1 - 0.19 12.1 2.1 1.2 9.5 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) MORN PF02493.15 CBZ26625.1 - 1.1e-18 65.7 17.0 6.6e-06 25.5 0.0 7.0 7 0 0 7 7 7 4 MORN repeat WW PF00397.21 CBZ26625.1 - 0.008 16.0 0.3 0.021 14.6 0.2 1.7 1 0 0 1 1 1 1 WW domain RWD PF05773.17 CBZ26627.1 - 5.2e-10 39.2 0.5 9.1e-10 38.4 0.4 1.4 1 0 0 1 1 1 1 RWD domain CTDII PF01556.13 CBZ26628.1 - 3.1e-12 46.1 0.0 5.2e-07 29.4 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBZ26628.1 - 5.1e-10 39.2 10.4 1.1e-09 38.2 7.2 1.6 1 0 0 1 1 1 1 DnaJ central domain CTP_synth_N PF06418.9 CBZ26629.1 - 3.3e-109 364.2 0.0 4.5e-109 363.8 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CBZ26629.1 - 1.2e-42 145.5 0.0 2.5e-42 144.4 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CBZ26629.1 - 1.3e-08 34.5 0.1 5.9e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 CBZ26629.1 - 0.00035 20.0 0.0 0.00074 18.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MORN PF02493.15 CBZ26631.1 - 8.4e-23 78.6 37.4 1e-06 28.0 0.2 6.7 7 0 0 7 7 7 6 MORN repeat NTP_transf_2 PF01909.18 CBZ26633.1 - 0.025 14.8 0.0 0.047 14.0 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Kinesin PF00225.18 CBZ26636.1 - 3.1e-80 269.4 1.9 2.6e-73 246.6 0.0 3.0 3 0 0 3 3 3 2 Kinesin motor domain FtsA PF14450.1 CBZ26636.1 - 0.065 13.0 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 Cell division protein FtsA TBPIP PF07106.8 CBZ26636.1 - 0.78 9.2 11.4 3.4 7.1 0.8 3.5 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPR_14 PF13428.1 CBZ26637.1 - 2.1e-06 27.8 6.4 7.1 7.5 0.0 5.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ26637.1 - 0.0005 19.6 0.4 0.0069 16.0 0.5 2.6 2 1 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 CBZ26637.1 - 0.0045 17.2 0.4 0.3 11.4 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat Retro_M PF02813.9 CBZ26637.1 - 0.04 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral M domain Suf PF05843.9 CBZ26637.1 - 0.046 13.4 4.3 2.7 7.6 0.0 3.3 2 2 1 3 3 3 0 Suppressor of forked protein (Suf) TPR_2 PF07719.12 CBZ26637.1 - 0.34 10.9 3.6 39 4.4 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ26637.1 - 8.7 7.1 0.0 8.7 7.1 0.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat HEAT PF02985.17 CBZ26638.1 - 2.6e-25 86.1 43.3 0.002 18.0 0.1 13.3 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.1 CBZ26638.1 - 3.5e-25 88.1 24.7 2.8e-06 27.5 0.2 6.8 3 1 4 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 CBZ26638.1 - 1.2e-09 38.3 30.2 0.0072 16.7 0.0 9.5 6 3 6 12 12 12 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CBZ26638.1 - 7.9e-07 29.3 0.4 0.012 15.9 0.0 5.7 2 1 4 7 7 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CBZ26638.1 - 0.00034 20.0 3.6 0.082 12.2 0.5 4.2 1 1 3 5 5 5 1 CLASP N terminal Adaptin_N PF01602.15 CBZ26638.1 - 0.00062 18.2 8.2 0.094 11.0 3.9 3.3 2 1 1 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.2 CBZ26638.1 - 0.013 15.3 0.7 33 4.2 0.0 4.5 2 1 3 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Acyl-CoA_dh_C PF12806.2 CBZ26639.1 - 0.0005 19.9 1.0 0.00084 19.1 0.7 1.3 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Tfb2 PF03849.9 CBZ26639.1 - 0.0045 15.6 1.6 0.006 15.2 1.1 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 DUF2721 PF11026.3 CBZ26639.1 - 2.1 8.0 3.7 1.2 8.7 1.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF775 PF05603.7 CBZ26640.1 - 8.1e-37 126.7 0.0 9.9e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Pkinase PF00069.20 CBZ26644.1 - 4.7e-56 189.8 0.0 7.6e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26644.1 - 8.4e-37 126.6 0.0 1.3e-36 126.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.24 CBZ26644.1 - 6.5e-15 54.7 0.0 4.9e-06 26.2 0.0 3.8 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain PAS PF00989.19 CBZ26644.1 - 4.3e-07 29.7 0.3 1.4e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 PAS fold Kinase-like PF14531.1 CBZ26644.1 - 7e-06 25.1 0.0 0.00023 20.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PAS_9 PF13426.1 CBZ26644.1 - 0.00072 19.9 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 CBZ26644.1 - 0.0028 17.6 0.1 0.019 15.0 0.0 2.5 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.1 CBZ26644.1 - 0.2 11.6 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 PAS domain Tubulin_3 PF14881.1 CBZ26645.1 - 1.3e-05 24.7 0.0 3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CBZ26645.1 - 0.00095 19.2 0.0 0.0018 18.3 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain CDC45 PF02724.9 CBZ26645.1 - 1.9 6.4 5.3 2.8 5.8 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TTL PF03133.10 CBZ26646.1 - 3e-48 164.2 0.0 1.1e-45 155.7 0.0 2.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Snf7 PF03357.16 CBZ26647.1 - 0.0017 17.7 1.2 0.0017 17.7 0.8 4.4 2 2 2 4 4 4 2 Snf7 Leptin PF02024.10 CBZ26647.1 - 0.018 14.6 1.0 0.035 13.7 0.7 1.4 1 0 0 1 1 1 0 Leptin AAA_14 PF13173.1 CBZ26647.1 - 0.088 12.7 1.2 0.17 11.7 0.8 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CBZ26648.1 - 2.1e-49 167.1 0.0 1e-36 126.0 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ26648.1 - 3e-12 47.4 0.3 1.9e-05 25.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CBZ26648.1 - 3.8e-09 36.7 1.9 0.014 15.5 0.9 4.3 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CBZ26648.1 - 8e-09 35.1 0.4 0.0011 18.6 0.0 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_16 PF13191.1 CBZ26648.1 - 1.4e-07 31.6 0.1 0.0048 16.9 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CBZ26648.1 - 1.7e-07 31.0 0.0 0.002 17.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CBZ26648.1 - 3.3e-07 30.6 0.1 0.022 15.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.8 CBZ26648.1 - 3.4e-06 26.0 0.0 0.019 13.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Mg_chelatase PF01078.16 CBZ26648.1 - 1.2e-05 24.6 0.0 0.0026 16.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CBZ26648.1 - 0.00015 20.8 0.0 0.038 13.0 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CBZ26648.1 - 0.00017 21.4 0.0 1 9.2 0.0 3.2 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 CBZ26648.1 - 0.00019 21.5 0.0 0.19 11.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Sigma54_activ_2 PF14532.1 CBZ26648.1 - 0.00027 21.0 0.0 0.63 10.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 CBZ26648.1 - 0.00029 20.7 0.0 0.5 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CBZ26648.1 - 0.00033 20.3 0.1 0.26 10.9 0.0 3.7 3 1 0 3 3 3 1 NACHT domain AAA_3 PF07726.6 CBZ26648.1 - 0.00036 20.1 0.0 0.24 10.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBZ26648.1 - 0.00057 19.4 0.0 0.25 10.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 CBZ26648.1 - 0.0013 17.9 0.0 1.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 CBZ26648.1 - 0.0013 18.7 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CBZ26648.1 - 0.0013 18.2 0.0 0.047 13.0 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein DUF2075 PF09848.4 CBZ26648.1 - 0.0014 17.7 0.1 1.5 7.7 0.1 2.5 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_2 PF07724.9 CBZ26648.1 - 0.0026 17.6 0.0 0.014 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.1 CBZ26648.1 - 0.0049 16.4 0.0 4.1 6.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain KTI12 PF08433.5 CBZ26648.1 - 0.0065 15.7 0.1 4.8 6.3 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 T2SE PF00437.15 CBZ26648.1 - 0.0069 15.3 0.0 1.9 7.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_11 PF13086.1 CBZ26648.1 - 0.01 15.4 0.0 1.2 8.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CBZ26648.1 - 0.014 15.7 0.1 0.87 9.8 0.0 3.0 2 1 1 3 3 3 0 ABC transporter AAA_24 PF13479.1 CBZ26648.1 - 0.014 14.9 0.1 0.18 11.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CBZ26648.1 - 0.023 14.3 0.3 2.4 7.8 0.1 3.2 2 2 1 3 3 3 0 Archaeal ATPase KaiC PF06745.8 CBZ26648.1 - 0.026 13.6 0.1 1.5 7.8 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 CBZ26648.1 - 0.03 13.7 4.0 4.6 6.5 0.1 3.7 3 1 1 4 4 4 0 AAA domain PhoH PF02562.11 CBZ26648.1 - 0.033 13.4 0.0 0.92 8.7 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein CDC48_N PF02359.13 CBZ26648.1 - 0.074 12.9 0.0 0.4 10.6 0.0 2.2 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain CPT PF07931.7 CBZ26648.1 - 0.08 12.5 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.1 CBZ26648.1 - 0.083 12.4 0.2 6.4 6.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.10 CBZ26648.1 - 0.15 11.8 0.1 16 5.2 0.0 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit ACPS PF01648.15 CBZ26650.1 - 1.3e-10 41.0 0.0 2.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SCO1-SenC PF02630.9 CBZ26651.1 - 1.8e-30 105.7 0.1 1e-28 100.1 0.1 2.5 1 1 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 CBZ26651.1 - 0.0089 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBZ26651.1 - 0.08 12.6 0.2 1.4 8.6 0.2 2.3 1 1 0 1 1 1 0 AhpC/TSA family TruD PF01142.13 CBZ26652.1 - 3.4e-16 58.9 0.0 9.1e-15 54.1 0.0 2.9 3 1 0 3 3 3 1 tRNA pseudouridine synthase D (TruD) DEAD PF00270.24 CBZ26654.1 - 1.9e-28 99.0 1.5 4.5e-16 58.8 0.0 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ26654.1 - 1.5e-13 50.4 0.0 4.1e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ26654.1 - 1.3e-08 34.9 0.0 1.8e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBZ26654.1 - 0.08 13.0 0.1 5.2 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Elf1 PF05129.8 CBZ26655.1 - 1.4e-21 75.9 0.4 2.2e-21 75.3 0.2 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 CBZ26655.1 - 0.031 13.8 1.1 0.065 12.8 0.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Lar_restr_allev PF14354.1 CBZ26655.1 - 0.097 12.9 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar zinc_ribbon_4 PF13717.1 CBZ26655.1 - 0.11 12.1 1.0 0.24 11.1 0.7 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Elf1 PF05129.8 CBZ26656.1 - 1.3e-07 31.1 1.4 5.5e-07 29.1 0.9 1.9 1 1 0 1 1 1 1 Transcription elongation factor Elf1 like DUF2946 PF11162.3 CBZ26656.1 - 0.17 12.0 1.7 0.51 10.5 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Ribonuclease_3 PF00636.21 CBZ26657.1 - 0.00034 21.0 0.0 0.00099 19.5 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain AATF-Che1 PF13339.1 CBZ26659.1 - 9.2e-29 100.2 3.9 1.5e-28 99.5 0.0 3.3 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 CBZ26659.1 - 0.027 14.5 0.0 0.027 14.5 0.0 2.6 3 0 0 3 3 3 0 Apoptosis-antagonizing transcription factor, C-terminal DUF4379 PF14311.1 CBZ26662.1 - 8.1e-13 47.9 15.0 1.9e-07 30.7 6.3 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4379) SprT-like PF10263.4 CBZ26662.1 - 0.025 14.2 0.9 0.059 13.0 0.6 1.6 1 0 0 1 1 1 0 SprT-like family Pkinase PF00069.20 CBZ26663.1 - 1.5e-47 161.9 0.3 1.7e-31 109.2 0.1 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26663.1 - 1.1e-29 103.3 0.0 2.4e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ26663.1 - 0.0017 17.4 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like ARD PF03079.9 CBZ26664.1 - 3.5e-37 127.7 0.0 9.4e-37 126.3 0.0 1.7 2 0 0 2 2 2 1 ARD/ARD' family DUF953 PF06110.6 CBZ26664.1 - 2.7e-16 59.1 0.0 4.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Cupin_2 PF07883.6 CBZ26664.1 - 3.3e-09 36.1 0.0 6.1e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CBZ26664.1 - 5.4e-06 26.1 0.2 1.2e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 AraC-like ligand binding domain GPI PF06560.6 CBZ26664.1 - 0.022 13.8 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_1 PF00190.17 CBZ26664.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Cupin Glutaredoxin PF00462.19 CBZ26668.1 - 5.8e-12 45.4 0.0 8.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CBZ26668.1 - 0.013 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain SH3BGR PF04908.10 CBZ26668.1 - 0.067 13.1 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein BetaGal_dom4_5 PF13364.1 CBZ26668.1 - 0.094 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain zf-RING_2 PF13639.1 CBZ26676.1 - 0.00032 20.4 3.6 0.0009 19.0 2.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBZ26676.1 - 0.0069 16.4 12.2 0.019 15.0 8.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBZ26676.1 - 0.48 10.1 12.3 0.48 10.1 5.6 2.8 1 1 1 2 2 2 0 zinc-RING finger domain AAA_22 PF13401.1 CBZ26677.1 - 0.0013 18.8 0.1 0.0073 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CBZ26677.1 - 0.0048 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ26677.1 - 0.0072 17.1 0.0 0.022 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain MORN PF02493.15 CBZ26678.1 - 1.1e-11 43.6 14.7 0.00036 20.0 0.8 4.7 4 0 0 4 4 4 3 MORN repeat Phage_holin_6 PF10746.4 CBZ26678.1 - 0.16 11.7 0.1 0.57 9.9 0.0 2.0 1 0 0 1 1 1 0 Phage holin family 6 PI3_PI4_kinase PF00454.22 CBZ26680.1 - 2.3e-44 151.6 0.1 6.1e-44 150.2 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CBZ26680.1 - 9e-34 116.9 3.9 5.4e-33 114.4 2.0 2.5 2 0 0 2 2 2 1 FAT domain FATC PF02260.15 CBZ26680.1 - 1e-09 37.6 0.0 2.6e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 FATC domain TFCD_C PF12612.3 CBZ26680.1 - 8.9e-05 21.9 2.1 0.00046 19.6 0.1 3.3 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 CBZ26680.1 - 0.004 17.0 5.4 7.2 6.9 0.0 6.7 8 0 0 8 8 8 1 HEAT repeat V-ATPase_H_C PF11698.3 CBZ26680.1 - 0.067 13.1 0.9 3.6 7.5 0.0 3.1 3 0 0 3 3 3 0 V-ATPase subunit H DnaJ PF00226.26 CBZ26681.1 - 7.7e-19 67.2 1.9 9.4e-19 66.9 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.26 CBZ26681.1 - 0.0015 18.5 4.9 0.8 9.8 0.1 3.5 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CBZ26681.1 - 0.05 13.7 10.9 0.056 13.5 0.2 3.8 4 0 0 4 4 4 0 Myb-like DNA-binding domain DUF3138 PF11336.3 CBZ26681.1 - 4.8 5.2 6.6 0.5 8.4 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) YIF1 PF03878.10 CBZ26682.1 - 3.8e-30 104.8 11.2 4.5e-29 101.2 7.8 1.9 1 1 0 1 1 1 1 YIF1 Yip1 PF04893.12 CBZ26682.1 - 0.0018 17.8 18.7 0.0023 17.4 12.6 1.5 1 1 0 1 1 1 1 Yip1 domain PRP38 PF03371.10 CBZ26683.1 - 1.1e-11 44.6 0.0 1.7e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 PRP38 family Esterase PF00756.15 CBZ26685.1 - 9e-15 54.7 0.1 9.2e-14 51.4 0.0 2.1 1 1 0 1 1 1 1 Putative esterase CBM_48 PF02922.13 CBZ26685.1 - 0.065 13.2 0.2 0.24 11.4 0.1 2.0 1 1 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Peptidase_C2 PF00648.16 CBZ26687.1 - 4.1e-52 177.0 0.0 6.1e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ26687.1 - 4.7e-34 116.4 0.1 1e-33 115.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.17 CBZ26687.1 - 0.039 13.6 0.0 0.097 12.3 0.0 1.6 2 0 0 2 2 2 0 Calpain large subunit, domain III Peptidase_C2 PF00648.16 CBZ26688.1 - 7.4e-40 136.8 0.3 1.1e-39 136.1 0.2 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ26688.1 - 3.5e-22 78.3 0.1 8.9e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.17 CBZ26688.1 - 0.03 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Calpain large subunit, domain III Peptidase_C2 PF00648.16 CBZ26689.1 - 2e-46 158.3 0.0 3.3e-46 157.6 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ26689.1 - 7.2e-34 115.8 0.1 1.6e-33 114.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 CBZ26690.1 - 1.4e-40 139.1 0.0 2.1e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ26690.1 - 3.8e-25 87.8 0.0 7.8e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 CBZ26691.1 - 2.6e-27 95.5 0.0 3.8e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ26692.1 - 1.1e-23 83.2 0.0 1.4e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CBZ26693.1 - 4.4e-29 100.5 0.0 5e-29 100.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Raptor_N PF14538.1 CBZ26694.1 - 6.1e-10 39.1 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain DUF1935 PF09149.5 CBZ26695.1 - 7.6e-29 99.7 0.0 1.4e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CBZ26696.1 - 0.0027 17.6 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CBZ26697.1 - 1.4e-06 28.2 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CBZ26698.1 - 1.2e-30 105.5 0.1 1.5e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) NAP PF00956.13 CBZ26699.1 - 1.6e-19 70.0 0.5 2.1e-19 69.5 0.3 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Shadoo PF14999.1 CBZ26699.1 - 0.38 10.6 0.1 0.38 10.6 0.1 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Phage_Mu_Gam PF07352.7 CBZ26699.1 - 0.78 9.2 3.4 13 5.3 1.3 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Sipho_Gp157 PF05565.6 CBZ26699.1 - 3.8 7.0 7.9 11 5.5 1.7 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 DUF1935 PF09149.5 CBZ26700.1 - 2.7e-36 123.6 0.2 3.2e-36 123.4 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CBZ26701.1 - 3.4e-39 133.0 0.2 3.9e-39 132.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Pkinase PF00069.20 CBZ26703.1 - 5.6e-34 117.4 0.0 8.1e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26703.1 - 1.3e-17 63.7 0.0 2.2e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ26703.1 - 6.1e-05 22.1 0.0 0.00033 19.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Adaptin_N PF01602.15 CBZ26705.1 - 1.8e-62 211.3 6.6 2.4e-62 210.9 4.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 CBZ26705.1 - 3.6e-38 130.4 0.0 8.7e-38 129.1 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 CBZ26705.1 - 2.9e-37 127.2 0.2 1.1e-35 122.2 0.1 2.5 1 1 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 CBZ26705.1 - 3.1e-10 40.1 5.6 0.029 14.6 0.0 5.9 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.17 CBZ26705.1 - 1.8e-06 27.5 2.8 0.22 11.7 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.2 CBZ26705.1 - 0.00077 19.3 6.1 0.66 9.8 0.1 3.6 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 CBZ26705.1 - 0.041 13.7 0.3 12 5.8 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat RNase_PH PF01138.16 CBZ26706.1 - 0.016 15.5 0.2 0.13 12.5 0.0 2.2 2 1 0 2 2 2 0 3' exoribonuclease family, domain 1 PUF PF00806.14 CBZ26707.1 - 1.7e-17 61.8 0.1 0.0019 17.5 0.0 4.5 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat Striatin PF08232.7 CBZ26709.1 - 0.00012 22.3 7.2 0.0015 18.8 0.4 3.0 2 1 0 2 2 2 2 Striatin family Tropomyosin_1 PF12718.2 CBZ26709.1 - 0.0069 16.2 9.2 0.18 11.6 0.2 3.1 3 0 0 3 3 3 2 Tropomyosin like KLRAQ PF10205.4 CBZ26709.1 - 0.15 12.0 7.1 0.77 9.8 0.0 3.6 4 1 0 4 4 4 0 Predicted coiled-coil domain-containing protein Sipho_Gp157 PF05565.6 CBZ26709.1 - 0.28 10.7 3.2 0.56 9.7 0.5 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Ax_dynein_light PF10211.4 CBZ26709.1 - 0.42 10.4 10.1 2.2 8.0 0.4 3.1 3 0 0 3 3 3 0 Axonemal dynein light chain Spc24 PF08286.6 CBZ26709.1 - 0.82 9.3 7.6 6.4 6.5 0.2 3.1 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 DivIC PF04977.10 CBZ26709.1 - 1.4 8.4 13.1 0.12 11.9 0.2 3.2 3 0 0 3 3 3 0 Septum formation initiator BRE1 PF08647.6 CBZ26709.1 - 2.6 8.1 8.5 0.59 10.1 0.2 3.2 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase GCN5L1 PF06320.8 CBZ26709.1 - 3.2 7.6 11.9 0.75 9.6 0.4 3.5 2 1 1 3 3 3 0 GCN5-like protein 1 (GCN5L1) Arm PF00514.18 CBZ26710.1 - 9.5e-38 126.7 20.5 1e-06 28.3 0.0 9.1 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBZ26710.1 - 7.3e-25 87.0 14.8 1.3e-06 28.5 0.1 5.1 2 1 3 5 5 5 5 HEAT repeats HEAT PF02985.17 CBZ26710.1 - 7.9e-20 69.1 12.3 0.0042 17.0 0.0 8.3 9 0 0 9 9 9 6 HEAT repeat HEAT_EZ PF13513.1 CBZ26710.1 - 2e-16 59.9 21.3 0.00022 21.6 0.3 6.4 5 1 2 7 7 7 5 HEAT-like repeat Adaptin_N PF01602.15 CBZ26710.1 - 2.8e-11 42.4 0.9 2.1e-08 32.9 1.1 3.2 2 1 0 2 2 2 1 Adaptin N terminal region DNA_alkylation PF08713.6 CBZ26710.1 - 6.5e-09 35.6 0.1 0.0075 15.8 0.0 4.1 2 1 1 4 4 4 3 DNA alkylation repair enzyme Cnd1 PF12717.2 CBZ26710.1 - 7.2e-08 32.4 0.1 0.00018 21.4 0.0 3.3 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 CBZ26710.1 - 8.4e-08 30.9 3.5 0.0014 17.0 0.4 3.1 1 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 CBZ26710.1 - 3.6e-05 23.2 0.8 0.37 10.1 0.2 3.1 2 1 1 3 3 3 2 CLASP N terminal V-ATPase_H_C PF11698.3 CBZ26710.1 - 0.0017 18.2 0.6 0.5 10.2 0.2 3.9 3 2 2 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 CBZ26710.1 - 0.0025 18.1 13.1 0.68 10.5 1.5 6.0 5 1 0 5 5 5 1 PBS lyase HEAT-like repeat DUF3731 PF12531.3 CBZ26710.1 - 0.005 16.3 2.1 0.98 8.9 0.1 3.4 2 1 1 4 4 4 1 DNA-K related protein Vac14_Fab1_bd PF12755.2 CBZ26710.1 - 0.024 14.9 0.1 0.64 10.4 0.0 3.1 1 1 3 4 4 4 0 Vacuolar 14 Fab1-binding region OHCU_decarbox PF09349.5 CBZ26710.1 - 0.031 14.5 1.5 8.5 6.6 0.0 3.4 2 1 1 3 3 3 0 OHCU decarboxylase DUF3361 PF11841.3 CBZ26710.1 - 0.039 13.6 2.4 5.5 6.6 0.0 3.7 2 2 2 4 4 4 0 Domain of unknown function (DUF3361) XPC-binding PF09280.6 CBZ26710.1 - 0.054 12.9 0.0 37 3.8 0.0 3.9 3 0 0 3 3 3 0 XPC-binding domain SET PF00856.23 CBZ26713.1 - 0.019 15.2 0.0 0.19 12.0 0.0 2.0 1 1 0 1 1 1 0 SET domain ubiquitin PF00240.18 CBZ26715.1 - 7.4e-05 22.0 0.0 0.12 11.8 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin family DUF3450 PF11932.3 CBZ26715.1 - 0.0086 15.3 1.9 0.014 14.7 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) TBPIP PF07106.8 CBZ26715.1 - 0.092 12.2 1.0 0.15 11.6 0.7 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rabaptin PF03528.10 CBZ26715.1 - 0.12 12.2 4.0 0.29 11.0 2.8 1.6 1 0 0 1 1 1 0 Rabaptin Spc7 PF08317.6 CBZ26715.1 - 0.4 9.3 3.9 0.25 9.9 1.6 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2802 PF10975.3 CBZ26715.1 - 5.2 6.8 8.5 3.5 7.4 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) PPR_3 PF13812.1 CBZ26717.1 - 0.17 12.2 1.6 1 9.8 0.1 3.0 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Myotub-related PF06602.9 CBZ26718.1 - 3.8e-84 282.4 0.0 1.4e-83 280.5 0.0 1.8 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 CBZ26718.1 - 0.0031 17.7 0.0 0.0065 16.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family FYVE_2 PF02318.11 CBZ26718.1 - 0.01 15.6 4.6 0.027 14.3 3.2 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.16 CBZ26718.1 - 0.14 12.0 11.7 0.45 10.4 8.1 1.8 1 0 0 1 1 1 0 FYVE zinc finger C1_4 PF07975.7 CBZ26718.1 - 0.36 10.8 12.0 1.2 9.1 8.3 1.9 1 0 0 1 1 1 0 TFIIH C1-like domain HEAT_EZ PF13513.1 CBZ26719.1 - 0.018 15.4 1.5 0.24 11.9 0.0 3.7 3 1 1 4 4 4 0 HEAT-like repeat YwiC PF14256.1 CBZ26719.1 - 0.1 12.6 6.1 3.1 7.8 0.4 2.7 2 0 0 2 2 2 0 YwiC-like protein DNA_alkylation PF08713.6 CBZ26720.1 - 0.042 13.3 1.5 0.078 12.4 1.1 1.4 1 0 0 1 1 1 0 DNA alkylation repair enzyme PolyA_pol_RNAbd PF12627.2 CBZ26721.1 - 0.057 12.9 0.0 1.2 8.7 0.0 2.8 3 0 0 3 3 3 0 Probable RNA and SrmB- binding site of polymerase A DUF4456 PF14644.1 CBZ26722.1 - 1.6e-10 40.6 0.0 1.6e-10 40.6 0.0 3.6 5 0 0 5 5 5 1 Domain of unknown function (DUF4456) DUF4455 PF14643.1 CBZ26722.1 - 1.8e-08 33.5 0.5 1.8e-08 33.5 0.4 5.0 5 1 1 6 6 6 1 Domain of unknown function (DUF4455) V_ATPase_I PF01496.14 CBZ26722.1 - 9.9 3.8 6.5 29 2.3 4.4 1.7 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA PF00004.24 CBZ26723.1 - 5.3e-28 97.8 0.0 2.1e-26 92.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ26723.1 - 5.9e-05 23.2 0.0 0.0015 18.6 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ26723.1 - 0.0059 16.6 15.6 0.011 15.6 0.2 4.4 3 2 0 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 CBZ26723.1 - 0.0094 16.7 0.0 0.028 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBZ26723.1 - 0.014 15.6 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CBZ26723.1 - 0.024 14.1 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 CBZ26723.1 - 0.031 13.9 2.4 1.2 8.7 0.1 3.4 2 1 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 CBZ26723.1 - 0.035 13.9 0.5 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CBZ26723.1 - 0.051 12.6 0.2 1.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin TIP49 PF06068.8 CBZ26723.1 - 0.067 11.8 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus KAP_NTPase PF07693.9 CBZ26723.1 - 0.098 11.6 0.0 6 5.7 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain AAA_21 PF13304.1 CBZ26723.1 - 0.36 10.7 0.0 0.55 10.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.13 CBZ26725.1 - 3.3e-16 59.4 0.3 8.2e-16 58.1 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain SGS PF05002.10 CBZ26726.1 - 4e-30 103.4 0.4 6.1e-30 102.8 0.3 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.11 CBZ26726.1 - 3.6e-07 30.6 0.1 7.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 CS domain Ribosomal_S17 PF00366.15 CBZ26727.1 - 1.5e-26 92.2 1.0 2.6e-26 91.4 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 DnaB_2 PF07261.6 CBZ26728.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Replication initiation and membrane attachment Brix PF04427.13 CBZ26729.1 - 9.3e-33 113.4 0.0 1.3e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain CRA PF06589.6 CBZ26729.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Peptidase_C50 PF03568.12 CBZ26730.1 - 1.5e-29 102.8 0.0 2.5e-15 56.0 0.0 3.2 3 0 0 3 3 3 3 Peptidase family C50 CHAT PF12770.2 CBZ26730.1 - 4.8e-11 42.3 0.8 1.1e-05 24.7 0.1 2.6 2 0 0 2 2 2 2 CHAT domain SNAP PF14938.1 CBZ26731.1 - 1.1e-56 192.0 14.9 1.3e-56 191.8 10.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CBZ26731.1 - 1.1e-07 31.6 9.9 1.4e-06 28.1 1.2 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ26731.1 - 0.0017 17.9 12.6 0.016 14.8 2.1 3.1 3 1 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 CBZ26731.1 - 0.0068 16.1 9.4 0.031 14.0 0.4 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat DUF1033 PF06279.6 CBZ26731.1 - 0.013 15.2 1.2 0.013 15.2 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1033) TPR_7 PF13176.1 CBZ26731.1 - 0.015 15.0 2.4 4.7 7.2 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Kunitz_BPTI PF00014.18 CBZ26731.1 - 0.063 13.4 1.6 1.3 9.2 0.2 2.5 2 0 0 2 2 2 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Apc3 PF12895.2 CBZ26731.1 - 0.47 10.6 7.1 0.25 11.4 1.0 3.0 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CBZ26731.1 - 0.56 9.9 13.5 0.35 10.5 0.3 4.5 4 1 2 6 6 6 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 CBZ26731.1 - 0.64 9.4 4.3 0.4 10.1 0.4 2.5 2 1 0 2 2 2 0 Foie gras liver health family 1 TPR_16 PF13432.1 CBZ26731.1 - 1.1 9.9 11.4 6.8 7.4 0.5 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ26731.1 - 2.2 8.9 20.4 12 6.6 0.2 5.8 4 3 1 6 6 5 0 Tetratricopeptide repeat tRNA_U5-meth_tr PF05958.6 CBZ26733.1 - 8.6e-19 67.4 0.0 9.2e-18 64.0 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 CBZ26733.1 - 2.1e-13 50.1 0.0 4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ26733.1 - 4.7e-09 36.2 0.0 1.2e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ26733.1 - 5.8e-08 33.3 0.0 1.2e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ26733.1 - 3.4e-07 29.7 0.0 7.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CBZ26733.1 - 1.5e-06 28.5 0.0 3.4e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CBZ26733.1 - 1.8e-06 27.4 0.0 3.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.14 CBZ26733.1 - 4.9e-05 22.9 0.0 9.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 CBZ26733.1 - 0.00022 21.6 0.0 0.00059 20.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ26733.1 - 0.00041 19.5 0.2 0.001 18.2 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.5 CBZ26733.1 - 0.00068 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.12 CBZ26733.1 - 0.0026 16.8 0.0 0.005 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 CBZ26733.1 - 0.0074 15.4 0.1 0.012 14.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.8 CBZ26733.1 - 0.0093 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 TPMT PF05724.6 CBZ26733.1 - 0.022 14.1 0.0 0.084 12.3 0.0 1.8 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 CBZ26733.1 - 0.023 14.3 0.0 0.062 12.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.13 CBZ26733.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Peptidase_M16_C PF05193.16 CBZ26733.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase M16 inactive domain RNA_ligase PF09414.5 CBZ26735.1 - 3.6e-53 180.1 0.0 2.8e-52 177.2 0.0 2.0 2 0 0 2 2 2 1 RNA ligase OST-HTH PF12872.2 CBZ26736.1 - 0.012 15.3 0.0 0.031 14.1 0.0 1.6 2 0 0 2 2 2 0 OST-HTH/LOTUS domain Peptidase_M20 PF01546.23 CBZ26737.1 - 1.7e-24 86.4 0.0 2.1e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ26737.1 - 5.6e-10 38.9 0.0 1.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CBZ26737.1 - 0.048 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.23 CBZ26738.1 - 1.8e-29 102.5 0.1 2.2e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ26738.1 - 7.4e-10 38.5 0.0 2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CBZ26738.1 - 0.057 13.1 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.23 CBZ26739.1 - 4.2e-30 104.6 0.1 5.1e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ26739.1 - 7.8e-10 38.4 0.0 1.9e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CBZ26739.1 - 0.053 13.2 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 PPR_2 PF13041.1 CBZ26740.1 - 7.1e-15 54.7 7.2 1.7e-05 24.7 0.0 6.0 6 1 1 7 7 7 3 PPR repeat family PPR_3 PF13812.1 CBZ26740.1 - 8.1e-13 47.5 10.0 0.0031 17.6 0.0 8.1 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 CBZ26740.1 - 8.6e-05 21.9 0.0 0.12 11.8 0.0 4.5 5 0 0 5 5 5 1 PPR repeat PPR PF01535.15 CBZ26740.1 - 0.00014 21.5 8.1 0.82 9.7 0.6 5.7 7 0 0 7 7 7 2 PPR repeat YndJ PF14158.1 CBZ26741.1 - 0.057 12.4 2.2 0.07 12.1 1.5 1.1 1 0 0 1 1 1 0 YndJ-like protein Pkr1 PF08636.5 CBZ26741.1 - 0.078 13.0 8.9 0.1 12.6 6.2 1.1 1 0 0 1 1 1 0 ER protein Pkr1 DUF3730 PF12530.3 CBZ26742.1 - 0.039 13.8 0.1 0.27 11.1 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3730) CHORD PF04968.7 CBZ26744.1 - 1.8e-45 153.0 33.1 1.1e-22 80.0 8.5 2.3 2 0 0 2 2 2 2 CHORD Tetraspannin PF00335.15 CBZ26744.1 - 0.52 9.5 3.4 0.64 9.2 2.4 1.4 1 1 0 1 1 1 0 Tetraspanin family Histone PF00125.19 CBZ26745.1 - 8.9e-12 44.9 1.2 1.2e-11 44.5 0.8 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ26745.1 - 9.2e-06 25.6 0.2 1.2e-05 25.2 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CBZ26745.1 - 0.00042 19.9 0.0 0.00055 19.6 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated TAF PF02969.12 CBZ26745.1 - 0.0015 18.4 0.2 0.0022 17.9 0.1 1.2 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.10 CBZ26745.1 - 0.016 15.0 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sigma70_r4 PF04545.11 CBZ26745.1 - 0.072 12.4 0.6 0.13 11.5 0.4 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 CENP-S PF15630.1 CBZ26745.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S PCP_red PF08369.5 CBZ26745.1 - 2.3 8.1 6.4 1.4 8.8 0.8 2.4 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Methyltransf_12 PF08242.7 CBZ26746.1 - 2.6e-15 56.6 0.1 2.1e-13 50.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ26746.1 - 6.9e-13 48.6 0.0 9.9e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ26746.1 - 2.8e-12 46.9 0.0 2.3e-10 40.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ26746.1 - 4.7e-12 46.4 0.0 2.6e-11 44.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ26746.1 - 1.3e-11 44.2 0.0 6.1e-05 22.6 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ26746.1 - 4.6e-07 29.8 0.0 9.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ26746.1 - 2.3e-06 27.9 0.0 7.8e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CBZ26746.1 - 0.00072 20.3 0.0 0.002 18.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 CBZ26746.1 - 0.0016 17.8 0.0 0.0089 15.4 0.0 1.9 2 0 0 2 2 2 1 Nodulation protein S (NodS) DUF3419 PF11899.3 CBZ26746.1 - 0.021 13.5 0.0 0.042 12.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3419) zf-rbx1 PF12678.2 CBZ26747.1 - 3.1e-34 116.8 15.2 3.7e-34 116.6 10.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBZ26747.1 - 2.9e-17 62.2 11.6 3.5e-17 62.0 8.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBZ26747.1 - 5.3e-07 29.3 16.2 6.4e-06 25.8 11.2 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CBZ26747.1 - 0.00085 18.9 13.5 0.34 10.6 9.8 2.3 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ26747.1 - 0.0061 16.1 14.3 0.075 12.7 9.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ26747.1 - 0.093 12.7 15.5 1.8 8.6 10.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Bacteriocin_II PF01721.13 CBZ26747.1 - 0.1 12.1 2.2 0.18 11.3 1.5 1.4 1 0 0 1 1 1 0 Class II bacteriocin zf-HC5HC2H PF13771.1 CBZ26747.1 - 0.62 10.2 11.8 68 3.7 8.2 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 CBZ26747.1 - 0.64 9.7 14.6 8.9 6.1 10.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.1 CBZ26747.1 - 1.1 9.2 12.1 4.5 7.3 8.4 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 CBZ26747.1 - 2.9 7.9 12.7 16 5.5 8.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 CBZ26747.1 - 3.4 7.7 13.7 23 5.1 9.5 2.3 1 1 0 1 1 1 0 RING-like domain Baculo_PEP_C PF04513.7 CBZ26749.1 - 0.0026 17.5 0.5 1.6 8.5 0.0 2.4 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Rab5-bind PF09311.6 CBZ26749.1 - 0.01 15.7 3.0 1.6 8.6 1.0 2.1 1 1 1 2 2 2 0 Rabaptin-like protein DUF3450 PF11932.3 CBZ26749.1 - 0.017 14.4 6.8 1.1 8.4 1.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) Rootletin PF15035.1 CBZ26749.1 - 0.028 14.3 9.0 0.2 11.5 1.1 3.0 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.7 CBZ26749.1 - 0.039 13.7 4.6 3.1 7.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) AAA_9 PF12781.2 CBZ26749.1 - 0.041 12.7 0.6 0.32 9.7 0.2 2.1 2 1 0 2 2 2 0 ATP-binding dynein motor region D5 IncA PF04156.9 CBZ26749.1 - 0.042 13.4 7.3 0.048 13.2 3.4 1.9 1 1 0 2 2 2 0 IncA protein UPF0147 PF03685.8 CBZ26749.1 - 0.062 13.1 0.2 0.22 11.4 0.0 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0147) COG2 PF06148.6 CBZ26749.1 - 0.2 11.5 6.5 3 7.7 0.1 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.6 CBZ26749.1 - 0.22 11.4 3.6 6.6 6.7 0.1 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 CBZ26749.1 - 2.1 8.2 5.5 21 5.0 0.1 3.1 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.9 CBZ26749.1 - 2.8 7.8 9.7 1.7 8.6 5.1 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Syntaxin_2 PF14523.1 CBZ26749.1 - 5.3 7.1 7.5 41 4.2 1.4 3.2 2 1 1 3 3 3 0 Syntaxin-like protein BAR PF03114.13 CBZ26750.1 - 1.8e-06 27.6 5.9 2.5e-06 27.1 4.1 1.1 1 0 0 1 1 1 1 BAR domain OmpH PF03938.9 CBZ26750.1 - 0.0043 16.9 1.3 0.0043 16.9 0.9 1.7 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DivIVA PF05103.8 CBZ26750.1 - 0.0063 16.5 5.4 0.32 11.0 1.0 2.3 2 0 0 2 2 2 2 DivIVA protein DUF3584 PF12128.3 CBZ26750.1 - 0.031 11.6 4.0 0.074 10.3 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DGCR6 PF07324.6 CBZ26750.1 - 0.092 12.2 2.6 0.048 13.1 0.3 1.6 2 0 0 2 2 2 0 DiGeorge syndrome critical region 6 (DGCR6) protein GreA_GreB_N PF03449.10 CBZ26750.1 - 0.48 10.5 5.2 6.4 6.9 0.3 2.7 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal DegS PF05384.6 CBZ26750.1 - 0.64 9.2 9.1 0.63 9.2 0.1 2.6 2 1 0 2 2 2 0 Sensor protein DegS SNARE PF05739.14 CBZ26751.1 - 3.3e-08 33.0 3.5 5.3e-08 32.4 1.0 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin-6_N PF09177.6 CBZ26751.1 - 0.00073 19.8 1.1 0.0049 17.2 0.1 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal DUF1664 PF07889.7 CBZ26751.1 - 1.4 8.6 4.2 2.5 7.9 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.27 CBZ26753.1 - 2.2e-28 97.0 6.9 2.8e-11 42.8 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 CBZ26753.1 - 0.00072 17.8 4.2 0.035 12.2 0.3 3.0 2 1 1 3 3 3 2 Nucleoporin Nup120/160 VanZ PF04892.7 CBZ26754.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.7 1 1 0 1 1 1 0 VanZ like family DUF2189 PF09955.4 CBZ26754.1 - 0.044 13.7 1.1 0.11 12.4 0.3 1.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2189) Allexi_40kDa PF05549.6 CBZ26754.1 - 0.077 12.2 0.0 0.091 12.0 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Lysis_col PF02402.11 CBZ26754.1 - 9.2 5.9 6.1 0.65 9.6 0.3 1.9 2 0 0 2 2 2 0 Lysis protein MFS_1 PF07690.11 CBZ26755.1 - 3.2e-19 68.8 37.0 1.2e-18 66.9 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sigma_reg_N PF13800.1 CBZ26756.1 - 0.038 14.0 2.2 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF3043 PF11241.3 CBZ26756.1 - 0.2 11.2 0.1 0.2 11.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) UPF0542 PF15086.1 CBZ26756.1 - 0.29 10.8 4.1 0.21 11.3 1.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DUF2427 PF10348.4 CBZ26756.1 - 3.5 7.2 6.8 0.25 10.9 0.6 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) Calpain_III PF01067.17 CBZ26759.1 - 4.4e-55 185.3 0.0 3.3e-24 85.2 0.0 7.9 8 0 0 8 8 8 7 Calpain large subunit, domain III Peptidase_C2 PF00648.16 CBZ26759.1 - 3.6e-28 98.4 0.0 5.6e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF3876 PF12992.2 CBZ26759.1 - 0.11 12.4 0.0 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) Topoisom_bac PF01131.15 CBZ26760.1 - 3.2e-80 269.9 0.0 6.9e-80 268.8 0.0 1.5 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CBZ26760.1 - 2.1e-12 46.8 0.0 6.2e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 CBZ26760.1 - 0.006 16.5 0.0 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 Toprim domain FleQ PF06490.6 CBZ26760.1 - 0.015 15.4 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ ACDC PF14733.1 CBZ26760.1 - 0.14 12.3 0.0 1.3 9.2 0.0 2.4 3 0 0 3 3 3 0 AP2-coincident C-terminal Pkinase PF00069.20 CBZ26761.1 - 2.2e-54 184.3 0.0 3.4e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26761.1 - 4.6e-31 107.8 0.0 7.5e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ26761.1 - 0.00097 18.1 0.0 0.0026 16.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBZ26761.1 - 0.012 14.6 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Guanylate_cyc PF00211.15 CBZ26761.1 - 0.015 14.6 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain Pkinase PF00069.20 CBZ26763.1 - 1.4e-39 135.7 0.0 1.9e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26763.1 - 7e-14 51.5 0.0 1.6e-13 50.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ26763.1 - 0.00037 19.5 0.0 0.0006 18.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like LRR_6 PF13516.1 CBZ26764.1 - 1.2e-15 55.7 7.4 0.0047 16.8 0.0 10.1 12 0 0 12 12 12 4 Leucine Rich repeat LRR_8 PF13855.1 CBZ26764.1 - 1.4e-13 50.3 6.2 0.00036 20.2 0.0 7.0 6 1 1 7 7 7 3 Leucine rich repeat LRR_4 PF12799.2 CBZ26764.1 - 7e-13 47.8 3.8 0.022 14.3 0.0 7.5 6 2 0 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ26764.1 - 4e-07 29.1 9.5 16 6.0 0.0 9.9 11 0 0 11 11 11 1 Leucine Rich Repeat LRR_7 PF13504.1 CBZ26764.1 - 0.00078 19.2 19.1 7.8 7.1 0.0 10.5 11 0 0 11 11 11 1 Leucine rich repeat Neurensin PF14927.1 CBZ26764.1 - 0.037 13.4 0.2 0.11 11.8 0.1 1.9 2 0 0 2 2 2 0 Neurensin DUF1959 PF09218.5 CBZ26764.1 - 0.16 11.7 0.3 0.36 10.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1959) PUF PF00806.14 CBZ26765.1 - 0.0051 16.2 5.2 6.4 6.4 0.0 5.3 6 1 1 7 7 7 2 Pumilio-family RNA binding repeat CHAT PF12770.2 CBZ26766.1 - 3.4e-43 147.8 0.3 6.4e-43 146.9 0.2 1.5 1 0 0 1 1 1 1 CHAT domain LRR_6 PF13516.1 CBZ26766.1 - 4.4e-07 29.3 5.3 0.46 10.7 0.4 4.2 4 0 0 4 4 4 3 Leucine Rich repeat TPR_12 PF13424.1 CBZ26766.1 - 0.00091 19.1 3.5 0.00091 19.1 2.4 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ26766.1 - 0.44 10.4 4.0 6 6.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ26766.1 - 0.78 9.4 5.2 9.9 5.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_1 PF00560.28 CBZ26766.1 - 1 9.6 5.1 60 4.2 1.5 3.5 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.2 CBZ26766.1 - 1.1 9.0 7.5 5.7 6.6 1.6 2.8 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) TPR_11 PF13414.1 CBZ26766.1 - 7.2 6.3 17.3 1.4 8.6 0.3 4.6 3 2 2 5 5 5 0 TPR repeat MVP_shoulder PF11978.3 CBZ26768.1 - 2.6e-45 153.1 0.0 4.3e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.13 CBZ26768.1 - 3.5e-31 106.9 3.5 8.7e-12 44.8 0.1 5.5 5 0 0 5 5 5 3 Major Vault Protein repeat DUF3601 PF12208.3 CBZ26768.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) EF-hand_7 PF13499.1 CBZ26770.1 - 3e-13 49.7 0.1 1.6e-06 28.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ26770.1 - 1.2e-09 37.2 2.9 0.00075 19.1 0.0 3.2 3 1 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CBZ26770.1 - 1.6e-09 36.3 0.1 0.018 14.3 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 CBZ26770.1 - 1.6e-07 30.8 0.1 0.00047 19.7 0.1 3.2 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 CBZ26770.1 - 1.8e-05 24.5 0.2 0.0013 18.5 0.0 2.8 2 1 1 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 CBZ26770.1 - 0.0031 16.7 0.9 0.91 8.9 0.0 2.8 2 1 0 2 2 2 2 EF hand DUF3024 PF11225.3 CBZ26770.1 - 0.27 11.1 0.8 24 4.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) Actin PF00022.14 CBZ26771.1 - 2.2e-34 118.5 0.0 3.4e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Actin Hexokinase_1 PF00349.16 CBZ26772.1 - 2.4e-63 213.2 0.0 3.5e-63 212.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CBZ26772.1 - 6.5e-52 176.1 0.0 9.2e-52 175.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CBZ26773.1 - 1.6e-63 213.7 0.0 2.4e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CBZ26773.1 - 1.8e-52 177.9 0.0 2.7e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PPR_2 PF13041.1 CBZ26774.1 - 2.5e-14 52.9 0.4 2e-06 27.6 0.0 5.3 4 1 1 5 5 5 3 PPR repeat family PPR_3 PF13812.1 CBZ26774.1 - 1.9e-12 46.4 12.7 0.25 11.7 0.0 9.2 10 1 0 10 10 10 5 Pentatricopeptide repeat domain PPR PF01535.15 CBZ26774.1 - 1.3e-06 27.9 5.4 5.3 7.2 0.0 6.6 7 0 0 7 7 7 2 PPR repeat PPR_1 PF12854.2 CBZ26774.1 - 6.1e-05 22.4 1.5 0.11 11.9 0.0 4.5 4 0 0 4 4 4 1 PPR repeat Pkinase PF00069.20 CBZ26775.1 - 2.5e-46 157.9 0.0 4.1e-44 150.6 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26775.1 - 5.6e-30 104.2 0.0 4.7e-23 81.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 CBZ26775.1 - 2.3e-05 23.8 0.1 5.2e-05 22.6 0.1 1.5 2 0 0 2 2 2 1 RIO1 family LRR_4 PF12799.2 CBZ26777.1 - 0.0058 16.2 0.8 2.8 7.6 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) DUF2115 PF09888.4 CBZ26779.1 - 0.025 14.6 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF702 PF05142.7 CBZ26779.1 - 0.038 14.1 0.3 0.069 13.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) zf-U1 PF06220.7 CBZ26780.1 - 6.3e-05 22.4 5.2 0.00015 21.2 3.6 1.6 1 0 0 1 1 1 1 U1 zinc finger AKAP95 PF04988.7 CBZ26780.1 - 0.001 18.8 0.5 0.0016 18.2 0.3 1.3 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.3 CBZ26780.1 - 0.0052 16.9 1.4 0.014 15.5 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CBZ26780.1 - 0.11 12.8 1.9 2.3 8.7 1.3 2.5 1 1 0 1 1 1 0 C2H2-type zinc finger Vps51 PF08700.6 CBZ26781.1 - 4.1e-23 81.0 1.3 4.1e-23 81.0 0.9 2.2 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.1 CBZ26781.1 - 5.7e-11 42.4 2.0 3.3e-10 39.9 0.7 2.4 2 1 1 3 3 3 1 Exocyst complex component Sec5 Dor1 PF04124.7 CBZ26781.1 - 7.5e-07 27.9 2.3 1.5e-06 26.9 1.6 1.4 1 0 0 1 1 1 1 Dor1-like family Vps53_N PF04100.7 CBZ26781.1 - 2e-06 26.8 1.6 3.3e-06 26.1 1.1 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 CBZ26781.1 - 8.7e-05 21.5 3.7 0.00016 20.6 2.6 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 CBZ26781.1 - 0.0002 21.2 3.5 0.00027 20.7 1.0 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 CBZ26781.1 - 0.0044 16.9 2.5 0.0044 16.9 1.8 2.4 3 0 0 3 3 2 1 Golgi transport complex subunit 5 Prominin PF05478.6 CBZ26781.1 - 0.0083 13.7 0.7 0.014 12.9 0.5 1.3 1 0 0 1 1 1 1 Prominin Cluap1 PF10234.4 CBZ26781.1 - 0.065 12.4 4.7 0.26 10.4 0.6 2.3 2 0 0 2 2 2 0 Clusterin-associated protein-1 NPV_P10 PF05531.7 CBZ26781.1 - 0.35 11.1 3.4 1.4 9.2 0.4 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 CBZ26781.1 - 0.48 10.2 6.7 0.1 12.4 2.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PAT1 PF09770.4 CBZ26781.1 - 7.1 4.7 15.6 11 4.1 10.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_M16 PF00675.15 CBZ26782.1 - 1.1e-12 47.8 0.0 2.8e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBZ26782.1 - 2.2e-05 24.1 0.0 0.00032 20.4 0.0 2.6 2 1 0 2 2 2 1 Peptidase M16 inactive domain DUF607 PF04678.8 CBZ26783.1 - 1.8e-28 99.7 4.2 2e-28 99.5 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF607 CCDC92 PF14916.1 CBZ26784.1 - 0.023 14.2 0.1 0.052 13.1 0.1 1.6 1 0 0 1 1 1 0 Coiled-coil domain of unknown function RPAP2_Rtr1 PF04181.8 CBZ26785.1 - 3.1e-08 33.6 0.0 5.6e-07 29.5 0.0 2.3 1 1 0 1 1 1 1 Rtr1/RPAP2 family DUF667 PF05018.8 CBZ26786.1 - 2.7e-102 339.8 0.6 3e-102 339.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) PDDEXK_1 PF12705.2 CBZ26787.1 - 4.2e-05 23.0 0.0 8.4e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UCH PF00443.24 CBZ26788.1 - 7.1e-54 182.7 0.6 9.6e-54 182.2 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ26788.1 - 2.4e-21 76.4 1.9 5.3e-21 75.3 1.3 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alpha-2-MRAP_N PF06400.6 CBZ26788.1 - 0.00079 19.0 1.4 0.0015 18.1 1.0 1.4 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, N-terminal domain Piwi PF02171.12 CBZ26789.1 - 1.2e-07 31.0 0.0 1.9e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain Pyr_redox_3 PF13738.1 CBZ26790.1 - 7.8e-06 26.0 0.0 0.0087 16.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CBZ26790.1 - 8.7e-06 25.7 0.0 0.00015 21.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ26790.1 - 4.8e-05 23.2 0.0 0.0002 21.3 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CBZ26790.1 - 0.0011 19.3 0.0 0.23 11.8 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CBZ26790.1 - 0.0011 18.7 0.0 0.0027 17.4 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 CBZ26790.1 - 0.019 14.5 0.3 0.042 13.4 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 CBZ26790.1 - 0.05 12.5 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 CBZ26790.1 - 0.12 12.4 0.6 23 5.0 0.0 3.4 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase MRP-S31 PF15433.1 CBZ26791.1 - 0.088 12.2 1.3 0.13 11.6 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Kua-UEV1_localn PF10520.4 CBZ26792.1 - 2.9e-72 242.0 2.6 3.9e-72 241.6 1.8 1.1 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain FA_hydroxylase PF04116.8 CBZ26792.1 - 0.79 10.1 9.5 4.8 7.6 0.3 2.4 1 1 2 3 3 3 0 Fatty acid hydroxylase superfamily Vps35 PF03635.12 CBZ26795.1 - 3.9e-246 818.9 0.0 4.6e-246 818.7 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF4611 PF15387.1 CBZ26795.1 - 4.8 7.3 9.5 0.27 11.4 1.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF972 PF06156.8 CBZ26796.1 - 0.059 13.7 6.3 0.73 10.2 0.5 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF972) CALCOCO1 PF07888.6 CBZ26796.1 - 0.13 10.5 18.3 0.011 14.0 8.8 1.9 2 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin PF00261.15 CBZ26796.1 - 0.39 9.7 23.8 0.12 11.4 0.1 3.3 2 1 1 3 3 3 0 Tropomyosin GAS PF13851.1 CBZ26796.1 - 1.6 7.9 8.1 0.57 9.3 0.1 3.0 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ERM PF00769.14 CBZ26796.1 - 3.7 6.9 20.0 22 4.4 13.8 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DnaJ PF00226.26 CBZ26797.1 - 9.6e-27 92.5 1.2 1.7e-26 91.7 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBZ26797.1 - 3.9e-18 65.1 0.0 1.6e-15 56.7 0.0 3.1 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBZ26797.1 - 2.9e-14 52.8 13.5 5.4e-14 52.0 9.4 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CBZ26797.1 - 0.28 10.8 3.9 1.1 8.9 0.4 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 CBZ26797.1 - 1.8 8.4 10.8 26 4.7 1.0 2.4 1 1 1 2 2 2 0 Double zinc ribbon Herpes_UL21 PF03252.8 CBZ26799.1 - 0.0054 15.2 0.4 0.01 14.3 0.3 1.3 1 0 0 1 1 1 1 Herpesvirus UL21 PQQ_3 PF13570.1 CBZ26800.1 - 0.049 13.9 1.1 0.34 11.2 0.1 3.0 3 0 0 3 3 3 0 PQQ-like domain TPR_11 PF13414.1 CBZ26801.1 - 2.7e-15 55.7 10.3 2.1e-05 24.0 0.0 6.4 3 2 3 6 6 6 4 TPR repeat TPR_14 PF13428.1 CBZ26801.1 - 4.2e-15 54.8 21.1 0.0077 16.7 0.1 8.9 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ26801.1 - 3e-14 53.0 9.7 0.00036 20.7 0.0 6.1 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ26801.1 - 1.5e-10 40.1 15.5 0.0091 15.8 0.4 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ26801.1 - 4.9e-10 38.5 5.1 0.011 15.3 0.4 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ26801.1 - 1e-09 38.7 27.3 0.003 18.1 0.4 7.9 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ26801.1 - 1.1e-09 38.1 13.1 0.014 15.3 0.1 6.4 5 1 1 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 CBZ26801.1 - 1.4e-08 34.7 6.3 0.0091 16.1 0.1 4.8 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CBZ26801.1 - 9.2e-06 25.0 0.1 2.4 8.1 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ26801.1 - 3e-05 23.4 4.0 7.3 6.6 0.1 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ26801.1 - 0.0055 16.5 12.7 0.13 12.1 0.1 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ26801.1 - 0.06 13.8 12.7 7 7.3 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ26801.1 - 0.27 11.2 13.6 1.1 9.2 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat NARP1 PF12569.3 CBZ26801.1 - 0.36 9.5 0.0 17 4.0 0.0 2.3 1 1 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_17 PF13431.1 CBZ26801.1 - 0.87 9.9 16.3 36 4.8 0.0 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_20 PF14561.1 CBZ26801.1 - 1.4 9.0 4.5 5.7 7.1 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat La PF05383.12 CBZ26802.1 - 1.8e-21 75.6 0.1 4.3e-21 74.4 0.0 1.7 2 0 0 2 2 2 1 La domain RRM_6 PF14259.1 CBZ26802.1 - 3.2e-05 23.8 0.0 0.018 14.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ26802.1 - 9.1e-05 22.0 0.3 0.015 14.9 0.0 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ26802.1 - 0.015 15.1 0.1 5.3 6.9 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 CBZ26802.1 - 0.032 12.7 3.3 0.058 11.8 2.3 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Biotin_lipoyl PF00364.17 CBZ26803.1 - 6.3e-26 89.8 1.6 8.9e-12 44.4 0.1 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme DUF2118 PF09891.4 CBZ26803.1 - 0.0013 18.4 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2118) QRPTase_N PF02749.11 CBZ26803.1 - 0.0018 18.0 0.1 2.4 8.0 0.0 2.6 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, N-terminal domain E3_binding PF02817.12 CBZ26803.1 - 0.0048 16.4 0.2 0.031 13.8 0.2 2.5 1 1 0 1 1 1 1 e3 binding domain HlyD_3 PF13437.1 CBZ26803.1 - 0.0051 17.1 0.1 5.5 7.3 0.0 2.7 2 1 0 2 2 2 2 HlyD family secretion protein PYNP_C PF07831.8 CBZ26803.1 - 0.006 16.0 0.4 5.5 6.5 0.0 2.8 3 0 0 3 3 3 2 Pyrimidine nucleoside phosphorylase C-terminal domain DUF902 PF06001.8 CBZ26803.1 - 0.046 13.8 0.0 16 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF902) DUF2969 PF11184.3 CBZ26803.1 - 0.049 13.7 0.5 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2969) TALPID3 PF15324.1 CBZ26803.1 - 0.18 9.1 10.7 0.12 9.7 1.0 2.1 2 0 0 2 2 2 0 Hedgehog signalling target SNARE PF05739.14 CBZ26804.1 - 5.2e-08 32.4 5.6 6.3e-08 32.2 3.9 1.1 1 0 0 1 1 1 1 SNARE domain ocr PF08684.5 CBZ26804.1 - 0.071 13.1 0.6 1.2 9.1 0.0 2.1 1 1 1 2 2 2 0 DNA mimic ocr Synaptobrevin PF00957.16 CBZ26804.1 - 0.08 12.5 0.3 0.1 12.2 0.2 1.2 1 0 0 1 1 1 0 Synaptobrevin SlyX PF04102.7 CBZ26804.1 - 3.5 8.0 5.1 3.4 8.0 0.4 2.1 1 1 1 2 2 2 0 SlyX DEAD PF00270.24 CBZ26809.1 - 1.5e-15 57.0 0.0 6e-12 45.3 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ26809.1 - 3.6e-14 52.3 0.0 8.4e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ26809.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MSP1_C PF07462.6 CBZ26809.1 - 0.81 7.9 3.7 8.1 4.6 0.1 2.2 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Med3 PF11593.3 CBZ26809.1 - 0.9 8.7 9.7 7.8 5.6 3.6 2.4 2 1 0 2 2 2 0 Mediator complex subunit 3 fungal IMS PF00817.15 CBZ26810.1 - 3.1e-49 166.5 0.4 4.9e-49 165.9 0.3 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 CBZ26810.1 - 0.003 17.4 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif IMS_C PF11799.3 CBZ26810.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain PGM_PMM_I PF02878.11 CBZ26811.1 - 1.2e-31 109.0 0.1 2e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CBZ26811.1 - 8.6e-25 86.9 0.0 2e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CBZ26811.1 - 3.9e-11 42.8 0.0 9.2e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 CBZ26811.1 - 3e-10 40.3 0.3 4.2e-09 36.6 0.2 2.6 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ParA PF10609.4 CBZ26813.1 - 2e-33 114.1 0.0 4e-33 113.1 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CBZ26813.1 - 2.8e-18 66.0 0.0 3.8e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 CBZ26813.1 - 8.9e-07 28.9 0.0 2.3e-06 27.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 CBZ26813.1 - 1.1e-06 27.9 0.0 1.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 CBZ26813.1 - 0.002 17.2 2.6 0.0023 17.0 1.0 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 CBZ26813.1 - 0.0029 16.4 0.4 0.0046 15.7 0.2 1.2 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 CBZ26813.1 - 0.0043 17.8 0.0 0.0072 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBZ26813.1 - 0.0068 15.8 0.1 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 CBZ26813.1 - 0.0095 15.1 0.1 0.021 14.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBZ26813.1 - 0.013 15.5 0.1 0.022 14.7 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 CBZ26813.1 - 0.029 14.6 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CBZ26813.1 - 0.031 13.9 0.1 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CBZ26813.1 - 0.042 13.5 0.8 2.5 7.9 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain Fer4_NifH PF00142.13 CBZ26813.1 - 0.052 12.7 0.2 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.17 CBZ26813.1 - 0.068 12.0 0.2 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 CBZ26813.1 - 0.074 12.4 0.4 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 CBZ26813.1 - 0.16 11.4 0.7 0.45 9.9 0.2 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 CBZ26813.1 - 0.16 12.1 0.2 0.29 11.3 0.1 1.4 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 CBZ26813.1 - 0.19 11.2 1.8 0.24 10.9 0.3 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CBZ26813.1 - 0.19 11.3 0.6 0.33 10.5 0.4 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 CBZ26813.1 - 0.24 10.9 3.5 0.34 10.4 0.2 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain Lactamase_B PF00753.22 CBZ26814.1 - 1.4e-25 90.1 0.5 2.1e-25 89.5 0.1 1.5 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBZ26814.1 - 7.4e-06 25.6 0.1 4.3e-05 23.1 0.0 2.2 2 1 1 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CBZ26814.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Hist_deacetyl PF00850.14 CBZ26815.1 - 2.4e-65 220.8 0.1 3.2e-65 220.4 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DSPc PF00782.15 CBZ26817.1 - 1.8e-19 69.6 0.0 2.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ABC_tran PF00005.22 CBZ26818.1 - 9.4e-37 126.3 0.0 7.5e-18 65.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBZ26818.1 - 2.8e-15 57.0 1.0 0.011 15.7 0.0 4.7 4 1 1 5 5 5 3 AAA domain SMC_N PF02463.14 CBZ26818.1 - 9.6e-11 41.3 3.3 0.00088 18.5 0.2 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RLI PF04068.10 CBZ26818.1 - 2e-09 36.8 6.2 2e-09 36.8 4.3 1.8 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.22 CBZ26818.1 - 9.5e-08 31.3 4.4 9.7e-08 31.3 1.5 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.1 CBZ26818.1 - 8.9e-07 28.2 0.0 0.15 11.0 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 CBZ26818.1 - 2.4e-06 26.9 0.4 0.01 15.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CBZ26818.1 - 2.7e-05 24.5 0.9 0.0097 16.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ26818.1 - 3.1e-05 24.0 0.0 0.0094 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ26818.1 - 3.7e-05 23.8 0.5 0.0065 16.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 CBZ26818.1 - 7.5e-05 23.2 0.2 0.017 15.6 0.0 2.8 2 1 0 2 2 2 1 Miro-like protein UPF0079 PF02367.12 CBZ26818.1 - 7.8e-05 22.2 0.0 0.0009 18.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_6 PF12837.2 CBZ26818.1 - 8.6e-05 22.2 2.1 8.6e-05 22.2 1.5 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_17 PF13207.1 CBZ26818.1 - 0.00014 22.6 0.1 0.23 12.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 CBZ26818.1 - 0.00022 20.9 0.3 0.0072 16.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 CBZ26818.1 - 0.00025 20.5 0.0 0.56 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBZ26818.1 - 0.00025 20.2 0.0 0.1 11.7 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Fer4_21 PF14697.1 CBZ26818.1 - 0.00026 20.7 17.0 0.00063 19.5 11.8 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain AAA PF00004.24 CBZ26818.1 - 0.00032 20.8 0.2 0.024 14.8 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Fer4_7 PF12838.2 CBZ26818.1 - 0.00037 20.8 0.3 0.00037 20.8 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_28 PF13521.1 CBZ26818.1 - 0.00053 19.9 0.0 0.61 10.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 CBZ26818.1 - 0.00091 19.1 0.0 0.29 10.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 CBZ26818.1 - 0.0013 18.9 0.0 0.43 10.7 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_5 PF07728.9 CBZ26818.1 - 0.0013 18.4 0.3 0.45 10.2 0.0 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_10 PF13237.1 CBZ26818.1 - 0.0035 17.0 1.7 0.0035 17.0 1.2 2.3 1 1 1 2 2 2 1 4Fe-4S dicluster domain SRP54 PF00448.17 CBZ26818.1 - 0.0048 16.3 0.3 0.64 9.4 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 CBZ26818.1 - 0.0049 16.7 0.0 0.42 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ26818.1 - 0.0053 17.0 0.1 2.9 8.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.10 CBZ26818.1 - 0.0071 15.0 0.1 2.8 6.5 0.0 3.0 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein SbcCD_C PF13558.1 CBZ26818.1 - 0.0072 16.2 0.1 0.83 9.6 0.0 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 CBZ26818.1 - 0.0075 15.8 0.0 2.8 7.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 CBZ26818.1 - 0.0082 15.6 0.0 1.8 7.9 0.0 2.7 2 0 0 2 2 2 1 Virulence-associated protein E Fer4_2 PF12797.2 CBZ26818.1 - 0.0087 15.9 2.2 0.0087 15.9 1.5 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_3 PF12798.2 CBZ26818.1 - 0.014 15.9 4.7 0.014 15.9 3.2 2.6 2 0 0 2 2 1 0 4Fe-4S binding domain MobB PF03205.9 CBZ26818.1 - 0.022 14.4 0.6 1 9.0 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CBZ26818.1 - 0.045 13.5 0.4 4.4 7.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 CBZ26818.1 - 0.057 13.1 0.0 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 CBZ26818.1 - 0.059 13.3 0.2 5.5 6.9 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF815 PF05673.8 CBZ26818.1 - 0.14 11.0 0.1 5.6 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_13 PF13166.1 CBZ26818.1 - 0.14 10.6 2.8 0.37 9.1 0.0 2.4 3 0 0 3 3 2 0 AAA domain Fer4_9 PF13187.1 CBZ26818.1 - 0.14 12.4 14.2 0.75 10.1 10.0 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain NB-ARC PF00931.17 CBZ26818.1 - 0.15 10.9 0.4 4.5 6.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 CBZ26818.1 - 0.23 10.9 1.7 0.7 9.3 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_4 PF12800.2 CBZ26818.1 - 8.4 7.0 15.6 0.068 13.5 1.7 2.6 2 0 0 2 2 1 0 4Fe-4S binding domain Dabb PF07876.7 CBZ26819.1 - 0.013 15.8 0.0 0.45 11.0 0.0 2.5 3 0 0 3 3 3 0 Stress responsive A/B Barrel Domain Hpt PF01627.18 CBZ26819.1 - 0.051 13.5 1.4 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Hpt domain Leu_Phe_trans PF03588.9 CBZ26820.1 - 0.00015 20.9 0.0 0.0015 17.6 0.0 2.4 3 0 0 3 3 3 1 Leucyl/phenylalanyl-tRNA protein transferase Ribosomal_L36e PF01158.13 CBZ26821.1 - 7.5e-34 115.6 1.8 9.1e-34 115.3 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF543 PF04418.7 CBZ26822.1 - 2.4e-19 69.0 0.8 2.9e-19 68.7 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) DLH PF01738.13 CBZ26822.1 - 0.0054 16.0 0.1 0.0057 15.9 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family ATP-synt_C PF00137.16 CBZ26823.1 - 1.9e-16 59.6 13.1 1.9e-16 59.6 9.1 1.5 2 0 0 2 2 2 1 ATP synthase subunit C PCI PF01399.22 CBZ26825.1 - 8.3e-13 48.5 1.9 1.3e-12 47.9 0.2 2.3 2 0 0 2 2 2 1 PCI domain Vps39_1 PF10366.4 CBZ26825.1 - 1.1 9.3 8.6 6.4 6.8 1.6 3.3 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 Ras PF00071.17 CBZ26828.1 - 9.7e-46 155.1 0.0 1.2e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ26828.1 - 2.1e-19 70.1 0.0 2.9e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ26828.1 - 1.1e-10 41.0 0.0 2.2e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ26828.1 - 7e-07 28.8 0.0 1.6e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBZ26828.1 - 0.00025 20.2 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ26828.1 - 0.00038 20.4 0.0 0.00059 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CBZ26828.1 - 0.017 14.3 0.0 0.046 12.9 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CBZ26828.1 - 0.033 14.3 0.0 0.098 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF2617 PF10936.3 CBZ26828.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF2617 Not1 PF04054.10 CBZ26830.1 - 2.8e-111 372.0 8.4 5.3e-111 371.1 5.8 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CBZ26830.1 - 2.3e-30 105.2 0.3 8e-30 103.4 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) tRNA-synt_1g PF09334.6 CBZ26831.1 - 1.7e-114 382.5 0.3 2.3e-114 382.1 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CBZ26831.1 - 3.1e-18 65.1 2.8 1e-07 30.4 1.6 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CBZ26831.1 - 6e-08 32.1 0.1 0.0023 17.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 CBZ26831.1 - 0.042 12.6 0.9 0.35 9.6 0.3 2.4 2 1 1 3 3 3 0 tRNA synthetases class I (R) MKT1_N PF12247.3 CBZ26832.1 - 1.7e-21 76.3 0.0 3.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_C PF12246.3 CBZ26832.1 - 1.5e-14 53.5 0.0 2.6e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication vMSA PF00695.14 CBZ26832.1 - 0.12 11.5 0.0 0.12 11.5 0.0 2.5 3 0 0 3 3 3 0 Major surface antigen from hepadnavirus Pkinase PF00069.20 CBZ26833.1 - 7.5e-40 136.7 0.0 3.1e-39 134.7 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26833.1 - 1.5e-24 86.4 0.0 1.9e-14 53.4 0.0 3.6 4 0 0 4 4 4 3 Protein tyrosine kinase APH PF01636.18 CBZ26833.1 - 0.0085 15.8 0.1 0.032 13.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_M24 PF00557.19 CBZ26838.1 - 2.2e-43 148.2 0.1 3.3e-43 147.7 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 RCR PF12273.3 CBZ26839.1 - 0.002 18.6 1.7 0.061 13.8 0.0 2.4 2 0 0 2 2 2 2 Chitin synthesis regulation, resistance to Congo red Pribosyltran PF00156.22 CBZ26840.1 - 7.7e-13 48.2 0.0 1.1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.22 CBZ26841.1 - 2.3e-14 53.1 0.0 3e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pkinase PF00069.20 CBZ26842.1 - 3.7e-52 177.0 0.0 1.3e-36 126.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26842.1 - 2.5e-27 95.5 0.0 5.8e-18 64.8 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ26842.1 - 4.2e-09 35.7 0.0 8.1e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBZ26842.1 - 0.49 9.6 0.0 0.86 8.8 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL BAG PF02179.11 CBZ26843.1 - 0.00028 20.9 0.1 0.00063 19.7 0.1 1.6 1 0 0 1 1 1 1 BAG domain InaF-motif PF15018.1 CBZ26844.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 TRP-interacting helix HEAT PF02985.17 CBZ26847.1 - 0.00053 19.8 0.3 0.26 11.4 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 CBZ26847.1 - 0.096 13.2 8.4 5.8 7.5 0.3 4.3 4 0 0 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.1 CBZ26847.1 - 0.6 10.4 7.0 0.96 9.7 0.4 3.6 2 1 3 5 5 5 0 HEAT repeats HEAT_2 PF13646.1 CBZ26848.1 - 1.9e-10 40.8 0.4 0.00088 19.5 0.0 4.0 3 1 1 4 4 4 3 HEAT repeats DUF4042 PF13251.1 CBZ26848.1 - 4e-09 36.2 2.8 1.3e-05 24.6 0.2 4.8 4 1 0 4 4 4 2 Domain of unknown function (DUF4042) HEAT PF02985.17 CBZ26848.1 - 5.5e-07 29.1 3.3 0.49 10.6 0.0 6.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 CBZ26848.1 - 1.1e-05 25.7 17.5 0.0038 17.6 0.2 6.6 5 2 1 6 6 6 2 HEAT-like repeat Adaptin_N PF01602.15 CBZ26848.1 - 0.059 11.6 0.0 0.11 10.7 0.0 1.4 1 0 0 1 1 1 0 Adaptin N terminal region Ipi1_N PF12333.3 CBZ26848.1 - 0.079 12.9 0.1 1.1 9.2 0.0 3.0 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation ABC_tran PF00005.22 CBZ26849.1 - 2.6e-06 27.7 0.0 4.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 CBZ26849.1 - 7.7e-05 21.9 17.1 0.00012 21.2 11.8 1.3 1 0 0 1 1 1 1 ABC-2 type transporter PDR_CDR PF06422.7 CBZ26849.1 - 0.075 12.6 0.0 0.28 10.8 0.0 1.9 1 0 0 1 1 1 0 CDR ABC transporter zf-DHHC PF01529.15 CBZ26849.1 - 0.33 10.3 4.1 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase UPF0506 PF11703.3 CBZ26849.1 - 2.3 8.2 6.3 0.38 10.7 1.0 2.2 2 0 0 2 2 2 0 UPF0506 ATP1G1_PLM_MAT8 PF02038.11 CBZ26850.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF4499 PF14934.1 CBZ26851.1 - 1.3e-06 28.2 2.2 2.4e-06 27.4 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Ripply PF14998.1 CBZ26851.1 - 0.088 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcription Regulator MutS_V PF00488.16 CBZ26852.1 - 5.2e-34 117.6 0.0 1.2e-33 116.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CBZ26852.1 - 1.9e-16 60.4 0.0 5.9e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.12 CBZ26852.1 - 0.0014 18.6 0.1 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain II AAA_21 PF13304.1 CBZ26852.1 - 0.0042 17.0 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBZ26852.1 - 0.01 16.1 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 CBZ26852.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBZ26852.1 - 0.091 12.9 0.0 0.32 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain MutS_IV PF05190.13 CBZ26852.1 - 0.093 12.9 0.0 0.38 10.9 0.0 2.0 3 0 0 3 3 1 0 MutS family domain IV AAA PF00004.24 CBZ26852.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 CBZ26852.1 - 0.23 11.7 0.0 0.4 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBZ26852.1 - 0.26 12.0 0.0 0.59 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CBZ26852.1 - 0.27 10.9 0.0 0.49 10.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase tRNA-synt_2 PF00152.15 CBZ26854.1 - 1.7e-66 224.2 0.0 4.5e-66 222.9 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBZ26854.1 - 1.7e-09 37.4 0.0 3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBZ26854.1 - 2.6e-06 26.8 0.1 0.0075 15.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_edit PF04073.10 CBZ26857.1 - 1.1e-07 31.7 0.0 2.3e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Sugarporin_N PF11471.3 CBZ26857.1 - 0.12 12.0 0.3 0.27 10.9 0.2 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF3138 PF11336.3 CBZ26857.1 - 0.28 9.3 1.3 0.35 8.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Histone PF00125.19 CBZ26859.1 - 3.6e-17 62.2 0.0 5.2e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ26859.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1583 PF07622.6 CBZ26859.1 - 0.13 10.6 0.0 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1583) PDCD2_C PF04194.8 CBZ26861.1 - 1e-30 106.4 4.5 7.3e-24 84.2 0.1 2.7 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain DUF2620 PF10941.3 CBZ26861.1 - 0.051 13.6 0.6 0.2 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF2620 DUF4611 PF15387.1 CBZ26863.1 - 1.8 8.7 5.2 0.76 9.9 1.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Clathrin PF00637.15 CBZ26864.1 - 1.1e-12 47.8 21.7 0.019 14.5 0.0 10.4 5 3 6 12 12 12 3 Region in Clathrin and VPS WD40 PF00400.27 CBZ26864.1 - 3.6e-10 39.3 0.9 0.25 11.2 0.1 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat TPR_4 PF07721.9 CBZ26864.1 - 1.6e-06 27.9 5.5 0.86 10.2 0.0 8.1 7 1 1 8 8 8 1 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 CBZ26864.1 - 5.7e-06 25.3 11.6 0.00064 18.6 0.8 5.5 4 2 1 6 6 6 1 Coatomer WD associated region PPR PF01535.15 CBZ26864.1 - 0.00032 20.4 11.8 2.5 8.2 0.3 8.0 7 1 1 8 8 7 1 PPR repeat Apc3 PF12895.2 CBZ26864.1 - 0.0022 18.0 25.2 0.53 10.4 0.0 7.9 5 3 2 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CBZ26864.1 - 0.0026 17.4 26.8 1.1 9.2 0.0 11.4 12 3 2 14 14 14 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ26864.1 - 0.0054 16.6 38.4 0.72 9.8 0.2 10.3 10 1 1 11 11 11 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ26864.1 - 0.039 13.8 0.1 0.039 13.8 0.1 11.3 13 0 0 13 13 12 0 Tetratricopeptide repeat Apc4_WD40 PF12894.2 CBZ26864.1 - 0.092 12.2 0.0 2.7 7.5 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-ribbon_3 PF13248.1 CBZ26864.1 - 0.17 11.1 1.2 0.5 9.6 0.8 1.9 1 0 0 1 1 1 0 zinc-ribbon domain TPR_1 PF00515.23 CBZ26864.1 - 0.76 9.4 37.8 1 9.1 0.1 11.1 11 1 1 12 12 12 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ26864.1 - 0.91 10.3 47.1 9.1 7.2 0.0 15.5 14 6 3 18 18 15 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ26864.1 - 4 7.1 38.9 1.4 8.6 0.0 10.6 10 3 1 11 11 11 0 TPR repeat PPR_3 PF13812.1 CBZ26864.1 - 4.6 7.7 18.1 15 6.2 0.0 8.4 9 1 1 10 10 10 0 Pentatricopeptide repeat domain Tubulin PF00091.20 CBZ26867.1 - 1.5e-72 243.9 0.0 2.2e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ26867.1 - 2e-20 73.0 0.0 3.2e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.1 CBZ26867.1 - 0.0083 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Misat_Tub_SegII PF10644.4 CBZ26867.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Ax_dynein_light PF10211.4 CBZ26868.1 - 8.2e-50 169.2 2.4 1.2e-49 168.7 1.4 1.4 2 0 0 2 2 2 1 Axonemal dynein light chain CCDC66 PF15236.1 CBZ26869.1 - 0.00089 18.8 42.4 0.00089 18.8 29.4 1.7 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 66 Kinesin PF00225.18 CBZ26870.1 - 1.2e-85 287.2 0.3 2.1e-85 286.3 0.2 1.4 1 0 0 1 1 1 1 Kinesin motor domain Pox_A_type_inc PF04508.7 CBZ26870.1 - 3.8 7.5 10.0 27 4.9 1.0 4.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Ribosomal_L6 PF00347.18 CBZ26871.1 - 3.4e-28 97.9 3.4 7.3e-16 58.4 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Hormone_2 PF00123.15 CBZ26871.1 - 0.12 12.2 0.0 30 4.5 0.0 3.1 3 0 0 3 3 3 0 Peptide hormone Ribosom_S12_S23 PF00164.20 CBZ26872.1 - 2.6e-39 133.4 1.2 4e-39 132.8 0.8 1.3 1 1 0 1 1 1 1 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.20 CBZ26873.1 - 2.6e-39 133.4 1.2 4e-39 132.8 0.8 1.3 1 1 0 1 1 1 1 Ribosomal protein S12/S23 Pkinase PF00069.20 CBZ26874.1 - 1.4e-74 250.5 0.0 1.6e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26874.1 - 3.7e-34 117.9 0.0 4.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ26874.1 - 0.001 18.8 0.4 0.11 12.1 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ26874.1 - 0.0069 15.3 0.0 0.091 11.7 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 CBZ26874.1 - 0.0069 15.4 0.4 0.014 14.4 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn60_TCP1 PF00118.19 CBZ26875.1 - 3.6e-136 454.6 6.6 4.1e-136 454.4 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tau95 PF09734.4 CBZ26876.1 - 8.7e-83 278.1 0.0 1.1e-82 277.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit IQ PF00612.22 CBZ26877.1 - 7.9e-18 62.3 202.6 2.7e-05 23.4 0.1 26.2 25 1 2 27 27 27 16 IQ calmodulin-binding motif TPR_1 PF00515.23 CBZ26877.1 - 4.8e-05 22.7 0.0 0.81 9.3 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ26877.1 - 0.00072 19.4 21.5 0.0029 17.5 0.4 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat Ca_chan_IQ PF08763.6 CBZ26877.1 - 0.014 14.6 0.3 1.2 8.3 0.0 3.5 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain WD40 PF00400.27 CBZ26878.1 - 2.9e-15 55.4 10.6 0.00011 21.9 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CBZ26878.1 - 0.001 17.3 0.1 0.0032 15.6 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 CBZ26878.1 - 0.0037 16.4 0.0 0.11 11.5 0.0 2.3 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Reo_sigmaC PF04582.7 CBZ26879.1 - 0.0019 17.4 2.2 0.024 13.8 0.4 2.3 2 0 0 2 2 2 1 Reovirus sigma C capsid protein Peptidase_S64 PF08192.6 CBZ26879.1 - 6.1 5.0 5.3 9 4.4 3.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF342 PF03961.8 CBZ26879.1 - 8.1 4.7 6.8 2.4 6.4 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF342) LRR_8 PF13855.1 CBZ26883.1 - 4.3e-24 84.0 28.0 5.5e-07 29.2 1.0 5.3 3 2 5 8 8 8 7 Leucine rich repeat LRR_4 PF12799.2 CBZ26883.1 - 5.3e-18 64.2 9.2 1.6e-05 24.4 0.8 5.3 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ26883.1 - 4.1e-17 59.5 3.6 0.6 10.3 0.0 10.2 10 1 0 10 10 10 5 Leucine Rich Repeat LRR_6 PF13516.1 CBZ26883.1 - 0.007 16.3 11.4 33 4.9 0.0 7.8 10 0 0 10 10 10 0 Leucine Rich repeat LRRNT_2 PF08263.7 CBZ26883.1 - 0.016 15.2 0.2 0.047 13.6 0.1 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 CBZ26883.1 - 0.24 11.7 20.1 12 6.6 0.1 8.3 9 1 1 10 10 10 0 Leucine rich repeat Ribosomal_L1 PF00687.16 CBZ26884.1 - 8.4e-11 41.6 0.0 2.5e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family PIF1 PF05970.9 CBZ26885.1 - 7.9e-34 117.1 0.0 3.1e-23 82.2 0.0 3.7 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 CBZ26885.1 - 2.4e-09 37.0 2.5 1.2e-07 31.5 0.4 2.6 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 CBZ26885.1 - 4e-07 29.7 0.1 0.059 12.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CBZ26885.1 - 6.8e-07 28.9 3.7 7.6e-07 28.7 1.2 2.1 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 CBZ26885.1 - 0.00018 21.5 0.0 0.00045 20.3 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.16 CBZ26885.1 - 0.00029 20.0 0.3 0.00057 19.1 0.2 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DEAD PF00270.24 CBZ26885.1 - 0.00042 19.8 0.2 0.014 14.9 0.1 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_32 PF13654.1 CBZ26885.1 - 0.0036 16.0 0.0 0.0055 15.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 CBZ26885.1 - 0.0045 14.8 0.0 0.017 12.9 0.0 1.8 3 0 0 3 3 3 1 Helicase UvrD-helicase PF00580.16 CBZ26885.1 - 0.005 16.1 0.0 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 CBZ26885.1 - 0.0084 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_5 PF07728.9 CBZ26885.1 - 0.0093 15.7 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 CBZ26885.1 - 0.011 15.3 1.5 0.21 11.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 CBZ26885.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CBZ26885.1 - 0.018 13.9 0.0 0.064 12.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 CBZ26885.1 - 0.054 13.1 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 NTPase TK PF00265.13 CBZ26887.1 - 5.9e-62 208.3 0.7 7.3e-62 208.0 0.5 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.1 CBZ26887.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Cytochrome_C7 PF14522.1 CBZ26887.1 - 0.086 12.4 1.3 0.21 11.2 0.9 1.7 1 0 0 1 1 1 0 Cytochrome c7 Pox_A_type_inc PF04508.7 CBZ26888.1 - 0.037 13.8 14.5 0.23 11.3 0.6 5.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat WD40 PF00400.27 CBZ26889.1 - 1.7e-20 72.0 4.5 1.2e-07 31.3 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 CBZ26889.1 - 0.00079 19.1 0.0 3.4 7.4 0.0 3.6 4 1 0 4 4 4 2 Ciliary BBSome complex subunit 2, middle region DUF2974 PF11187.3 CBZ26889.1 - 0.042 13.1 0.2 0.078 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DivIC PF04977.10 CBZ26889.1 - 0.23 10.9 1.9 0.45 10.0 1.3 1.4 1 0 0 1 1 1 0 Septum formation initiator PQQ_3 PF13570.1 CBZ26889.1 - 0.54 10.6 0.1 0.54 10.6 0.1 5.3 7 0 0 7 7 7 0 PQQ-like domain WD40 PF00400.27 CBZ26890.1 - 1.8e-16 59.3 7.9 5.7e-08 32.3 0.0 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.1 CBZ26890.1 - 0.07 13.4 0.0 16 5.9 0.1 3.6 4 0 0 4 4 4 0 PQQ-like domain RasGAP PF00616.14 CBZ26890.1 - 0.54 9.8 6.1 4.1 7.0 0.1 2.7 1 1 1 2 2 2 0 GTPase-activator protein for Ras-like GTPase Rootletin PF15035.1 CBZ26890.1 - 0.78 9.6 61.5 0.56 10.1 2.9 5.4 4 1 1 5 5 5 0 Ciliary rootlet component, centrosome cohesion ADK PF00406.17 CBZ26891.1 - 4.3e-39 133.7 0.0 5.9e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CBZ26891.1 - 8.2e-06 26.1 0.0 5.5e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.9 CBZ26891.1 - 1.5e-05 24.5 0.0 3.8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CBZ26891.1 - 3.3e-05 24.6 0.0 9.4e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ26891.1 - 0.0013 18.6 0.0 0.0058 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CBZ26891.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CBZ26891.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain LRR_4 PF12799.2 CBZ26892.1 - 0.02 14.5 1.0 0.29 10.8 0.3 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBZ26892.1 - 0.02 14.9 0.6 18 5.8 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat DUF4124 PF13511.1 CBZ26892.1 - 0.11 12.5 2.3 1.2 9.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) LRR_8 PF13855.1 CBZ26892.1 - 1.1 9.0 3.2 4 7.2 0.6 2.5 1 1 1 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 CBZ26892.1 - 1.2 9.4 5.5 5.2 7.5 0.4 3.2 2 1 1 3 3 3 0 Leucine Rich Repeat Serine_rich PF08824.5 CBZ26893.1 - 0.014 15.0 0.0 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 Serine rich protein interaction domain SelR PF01641.13 CBZ26894.1 - 0.035 13.8 0.1 5.7 6.6 0.0 3.0 2 1 0 2 2 2 0 SelR domain Synaptobrevin PF00957.16 CBZ26895.1 - 1.7e-25 88.4 0.5 2.7e-25 87.7 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin zf-RING_2 PF13639.1 CBZ26896.1 - 1.5e-11 43.9 3.7 3.9e-09 36.2 0.9 2.5 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 CBZ26896.1 - 5.2e-09 36.0 0.4 7.7e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CBZ26896.1 - 3.9e-07 29.6 2.4 3.3e-06 26.6 0.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ26896.1 - 5.3e-05 23.1 5.8 7.7e-05 22.6 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBZ26896.1 - 0.00014 21.5 0.2 0.00027 20.6 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CBZ26896.1 - 0.00056 19.5 2.7 0.0023 17.5 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ26896.1 - 0.0052 16.4 1.7 0.02 14.6 0.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 CBZ26896.1 - 0.055 13.0 0.4 0.14 11.8 0.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBZ26896.1 - 1.5 8.7 5.9 0.5 10.2 0.8 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 CBZ26896.1 - 2.9 7.9 4.6 0.86 9.7 0.7 1.9 2 0 0 2 2 2 0 RING-variant domain RF-1 PF00472.15 CBZ26897.1 - 1.1e-10 41.2 0.5 1.1e-10 41.2 0.3 3.4 3 1 0 3 3 3 1 RF-1 domain CCDC155 PF14662.1 CBZ26897.1 - 0.00018 21.1 10.9 0.00018 21.1 7.5 3.4 3 0 0 3 3 3 1 Coiled-coil region of CCDC155 DUF4250 PF14056.1 CBZ26897.1 - 0.29 10.8 2.8 0.6 9.8 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4250) MxiH PF09392.5 CBZ26897.1 - 0.32 11.5 0.0 0.32 11.5 0.0 4.5 3 3 1 4 4 4 0 Type III secretion needle MxiH like Laminin_II PF06009.7 CBZ26897.1 - 1.5 8.5 13.7 1.9 8.2 6.9 3.1 2 1 1 3 3 3 0 Laminin Domain II DivIC PF04977.10 CBZ26897.1 - 6.3 6.3 19.7 1.1 8.7 1.1 4.5 3 1 1 4 4 4 0 Septum formation initiator EMP24_GP25L PF01105.19 CBZ26897.1 - 6.4 6.4 6.7 23 4.6 0.6 2.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD SMC_N PF02463.14 CBZ26900.1 - 5.1e-72 241.6 8.5 6.6e-71 238.0 5.9 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBZ26900.1 - 9.6e-22 77.2 0.0 3.9e-21 75.2 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBZ26900.1 - 5.7e-13 49.4 0.6 4.8e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBZ26900.1 - 6.4e-06 25.6 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CBZ26900.1 - 5.6e-05 22.3 0.1 0.0065 15.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain TIM21 PF08294.6 CBZ26900.1 - 0.062 12.9 1.1 0.21 11.2 0.8 1.9 1 0 0 1 1 1 0 TIM21 ABC_tran PF00005.22 CBZ26900.1 - 0.093 13.0 0.0 0.093 13.0 0.0 4.9 4 2 0 5 5 5 0 ABC transporter Reo_sigmaC PF04582.7 CBZ26900.1 - 1.5 7.9 4.9 13 4.7 0.1 2.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein V-ATPase_H_N PF03224.9 CBZ26901.1 - 2.7e-72 243.5 0.2 3.7e-72 243.0 0.1 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CBZ26901.1 - 3.1e-42 143.2 0.0 2e-41 140.6 0.0 2.2 2 0 0 2 2 2 1 V-ATPase subunit H PB1 PF00564.19 CBZ26902.1 - 5.3e-08 32.4 0.0 2e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 PB1 domain AA_permease_2 PF13520.1 CBZ26905.1 - 0.054 12.0 0.4 0.078 11.5 0.3 1.2 1 0 0 1 1 1 0 Amino acid permease zf-DHHC PF01529.15 CBZ26906.1 - 2.5e-32 111.6 0.7 2.5e-32 111.6 0.5 1.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF971 PF06155.7 CBZ26907.1 - 3.6e-17 62.5 0.0 2.3e-15 56.7 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF971) DUF393 PF04134.7 CBZ26908.1 - 0.00015 22.8 0.1 0.021 15.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF393 Toxin_22 PF08092.6 CBZ26908.1 - 0.032 14.0 2.7 0.07 12.9 1.2 2.0 2 0 0 2 2 2 0 Magi peptide toxin family E1_dh PF00676.15 CBZ26909.1 - 4.9e-79 265.1 0.0 6.3e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4440 PF14534.1 CBZ26909.1 - 0.067 13.4 0.0 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Cyt-b5 PF00173.23 CBZ26910.1 - 5.3e-09 35.7 0.0 8.5e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rad60-SLD PF11976.3 CBZ26910.1 - 0.0063 16.1 0.0 0.026 14.1 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like PRMT5 PF05185.11 CBZ26911.1 - 2.2e-71 241.0 0.0 3e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MIT PF04212.13 CBZ26913.1 - 0.00013 21.8 3.7 0.011 15.5 0.0 3.1 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 CBZ26913.1 - 0.00031 20.4 3.1 0.019 14.8 0.8 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ26913.1 - 0.00064 19.5 7.4 0.033 14.1 1.0 3.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ26913.1 - 0.0054 16.4 0.1 1.2 9.0 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ26913.1 - 0.029 14.0 5.0 0.38 10.4 2.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3529 PF12046.3 CBZ26913.1 - 0.034 13.1 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) Cas_DxTHG PF09455.5 CBZ26913.1 - 0.037 13.1 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family TPR_11 PF13414.1 CBZ26913.1 - 0.06 12.9 5.9 0.19 11.4 1.2 3.2 2 2 1 3 3 3 0 TPR repeat TPR_14 PF13428.1 CBZ26913.1 - 0.14 12.8 4.2 3.6 8.4 0.3 4.3 4 1 0 5 5 5 0 Tetratricopeptide repeat Hemerythrin PF01814.18 CBZ26913.1 - 0.16 12.1 1.6 0.69 10.0 0.0 2.7 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain TPR_6 PF13174.1 CBZ26913.1 - 1.5 9.4 5.1 14 6.3 0.5 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat HMG_box PF00505.14 CBZ26918.1 - 5.1e-08 33.0 3.1 0.025 14.8 0.9 4.1 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CBZ26918.1 - 1.3e-07 31.8 5.1 0.015 15.6 0.7 3.5 3 1 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.1 CBZ26918.1 - 0.061 13.1 0.5 0.97 9.2 0.1 2.6 3 0 0 3 3 3 0 HMG (high mobility group) box 5 DUF647 PF04884.9 CBZ26919.1 - 2.2e-78 262.9 0.5 3.1e-78 262.4 0.4 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Sec8_exocyst PF04048.9 CBZ26920.1 - 1e-10 41.4 0.1 2.4e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 CBZ26920.1 - 1.3e-05 24.2 0.3 2.2e-05 23.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Nucleoplasmin PF03066.10 CBZ26920.1 - 0.5 9.8 12.8 2.4 7.6 0.3 2.7 2 0 0 2 2 2 0 Nucleoplasmin Ribosomal_S17 PF00366.15 CBZ26921.1 - 1.5e-26 92.2 1.0 2.6e-26 91.4 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 DUF4018 PF13210.1 CBZ26922.1 - 0.00035 19.9 0.5 0.00057 19.3 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4018) DUF2232 PF09991.4 CBZ26922.1 - 0.0027 16.7 0.3 0.0055 15.7 0.2 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) DEAD PF00270.24 CBZ26923.1 - 3.1e-35 121.1 0.3 5.3e-34 117.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ26923.1 - 2.9e-22 78.3 0.5 1e-21 76.5 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ26923.1 - 4.3e-07 29.9 0.0 9.1e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CBZ26923.1 - 0.00044 19.4 0.2 0.003 16.6 0.0 2.4 3 1 1 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 CBZ26923.1 - 0.083 12.8 0.7 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Helicase C-terminal domain LETM1 PF07766.8 CBZ26924.1 - 1.8e-05 23.9 0.0 3.5e-05 22.9 0.0 1.4 2 0 0 2 2 2 1 LETM1-like protein Tn7_Tnp_TnsA_N PF08722.6 CBZ26924.1 - 0.0077 16.2 0.1 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 TnsA endonuclease N terminal GST_C_3 PF14497.1 CBZ26925.1 - 0.0032 17.9 0.0 0.0063 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GMC_oxred_C PF05199.8 CBZ26927.1 - 1.2e-12 48.3 0.1 1.6e-11 44.6 0.0 2.4 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 CBZ26927.1 - 4.2e-12 45.8 0.0 5.9e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 CBZ26927.1 - 2e-05 23.7 0.1 0.003 16.5 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 CBZ26927.1 - 5.3e-05 22.2 2.4 0.0012 17.8 0.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CBZ26927.1 - 0.0027 16.2 0.3 0.0041 15.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 CBZ26927.1 - 0.0049 15.7 0.0 0.012 14.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 CBZ26927.1 - 0.0057 16.6 0.3 0.0057 16.6 0.2 2.8 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CBZ26927.1 - 0.0067 15.5 0.7 0.0067 15.5 0.5 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 CBZ26927.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.20 CBZ26928.1 - 3.8e-68 229.4 0.0 7.4e-68 228.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26928.1 - 4.2e-45 153.8 0.0 7e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ26928.1 - 1.5e-06 27.4 0.0 4.3e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Kinase-like MIP-T3 PF10243.4 CBZ26929.1 - 3.2e-107 359.2 40.7 5e-69 233.2 5.0 2.1 1 1 1 2 2 2 2 Microtubule-binding protein MIP-T3 COMP PF11598.3 CBZ26929.1 - 4.5 7.4 5.7 1 9.4 0.9 2.1 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein CK2S PF15011.1 CBZ26930.1 - 0.044 13.5 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate peroxidase PF00141.18 CBZ26931.1 - 1.4e-09 37.7 0.0 6.8e-09 35.5 0.0 1.9 1 1 0 2 2 2 1 Peroxidase WD40 PF00400.27 CBZ26932.1 - 2.7 7.9 8.9 22 5.1 0.3 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Chordopox_A13L PF05961.6 CBZ26933.1 - 0.044 13.7 0.1 0.41 10.6 0.1 2.8 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Nodulin-like PF06813.8 CBZ26934.1 - 0.00036 19.8 8.1 0.00036 19.8 5.6 2.8 3 1 0 3 3 3 1 Nodulin-like MFS_1 PF07690.11 CBZ26934.1 - 0.13 10.8 58.4 0.0039 15.9 22.4 3.1 2 1 0 2 2 2 0 Major Facilitator Superfamily F-box-like PF12937.2 CBZ26935.1 - 5.9e-07 29.1 0.7 1.4e-06 27.9 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBZ26935.1 - 1.6e-06 27.6 1.1 4.6e-06 26.1 0.5 2.0 2 0 0 2 2 2 1 F-box domain TrbI_Ftype PF09677.5 CBZ26936.1 - 0.039 13.8 1.7 0.12 12.2 0.0 2.4 1 1 1 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF1507 PF07408.6 CBZ26936.1 - 0.046 13.4 2.4 5.9 6.7 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1507) GAS PF13851.1 CBZ26936.1 - 0.082 12.0 7.8 0.19 10.8 3.8 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Lge1 PF11488.3 CBZ26936.1 - 0.33 11.1 6.7 0.5 10.5 3.9 2.1 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF342 PF03961.8 CBZ26936.1 - 0.65 8.3 3.9 0.35 9.2 1.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DivIC PF04977.10 CBZ26936.1 - 0.82 9.1 4.2 11 5.5 2.4 2.7 3 1 0 3 3 3 0 Septum formation initiator SlyX PF04102.7 CBZ26936.1 - 2.1 8.8 5.3 5.6 7.4 1.1 3.1 3 1 0 3 3 3 0 SlyX DUF4140 PF13600.1 CBZ26936.1 - 2.3 8.7 5.7 35 4.9 0.0 2.7 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-Sec23_Sec24 PF04810.10 CBZ26937.1 - 0.015 14.8 0.2 0.015 14.8 0.2 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Lar_restr_allev PF14354.1 CBZ26937.1 - 1.6 9.0 5.6 0.7 10.2 1.2 2.2 2 1 1 3 3 3 0 Restriction alleviation protein Lar Rubredoxin PF00301.15 CBZ26937.1 - 2.2 8.2 5.8 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 Rubredoxin Rad60-SLD_2 PF13881.1 CBZ26938.1 - 1.3e-06 28.2 1.5 2.3e-05 24.2 1.1 2.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CBZ26938.1 - 0.001 19.2 0.0 0.0016 18.5 0.0 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain PPR_2 PF13041.1 CBZ26939.1 - 8.5e-09 35.2 0.1 2.2e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.1 CBZ26939.1 - 1.6e-05 24.7 2.8 6.8e-05 22.8 0.1 3.3 4 1 1 5 5 5 1 Pentatricopeptide repeat domain PPR PF01535.15 CBZ26939.1 - 6.4e-05 22.6 0.2 0.00025 20.7 0.0 2.1 2 0 0 2 2 2 1 PPR repeat EF-hand_7 PF13499.1 CBZ26940.1 - 7.5e-28 96.4 14.9 2.5e-11 43.5 1.4 2.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 CBZ26940.1 - 1.3e-23 80.4 7.1 1.5e-06 27.0 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CBZ26940.1 - 1.8e-17 61.5 7.6 0.00025 20.6 0.1 4.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 CBZ26940.1 - 3.2e-15 54.6 13.0 1.9e-06 26.9 0.2 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CBZ26940.1 - 9e-13 47.6 9.4 0.00012 21.6 0.9 4.3 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 CBZ26940.1 - 5.6e-08 32.4 1.9 0.049 13.3 0.1 3.5 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CBZ26940.1 - 4e-06 26.8 0.0 0.0027 17.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Capsule_synth PF05159.9 CBZ26940.1 - 0.0017 17.8 0.0 0.0025 17.3 0.0 1.1 1 0 0 1 1 1 1 Capsule polysaccharide biosynthesis protein DUF4447 PF14590.1 CBZ26940.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) Dockerin_1 PF00404.13 CBZ26940.1 - 2.3 8.0 10.3 2.1 8.1 0.2 3.5 3 0 0 3 3 3 0 Dockerin type I repeat VCBS PF13517.1 CBZ26940.1 - 3.8 7.9 6.6 23 5.4 0.1 3.1 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_8 PF13833.1 CBZ26941.1 - 0.04 13.5 0.0 8.3 6.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Pkinase PF00069.20 CBZ26942.1 - 1.5e-41 142.2 0.0 1.9e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ26942.1 - 1.7e-10 40.4 0.0 2.9e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase 5_3_exonuc PF01367.15 CBZ26943.1 - 6.6e-18 64.8 0.0 1.3e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 CBZ26943.1 - 3.9e-15 55.6 0.6 4.8e-12 45.5 0.5 3.0 1 1 1 2 2 2 2 5'-3' exonuclease, N-terminal resolvase-like domain zf-MYND PF01753.13 CBZ26945.1 - 0.0012 18.6 20.3 0.002 17.9 14.1 1.4 1 0 0 1 1 1 1 MYND finger PUF PF00806.14 CBZ26946.1 - 1.9e-48 159.2 4.0 8.4e-06 24.9 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HNOB PF07700.10 CBZ26946.1 - 0.012 15.1 0.1 2.4 7.6 0.1 3.3 2 1 0 2 2 2 0 Heme NO binding CPL PF08144.6 CBZ26946.1 - 0.14 12.0 0.1 16 5.3 0.0 3.5 3 1 1 4 4 4 0 CPL (NUC119) domain DUF607 PF04678.8 CBZ26947.1 - 1.1e-46 159.0 0.6 1.6e-46 158.5 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function, DUF607 Proteasome PF00227.21 CBZ26948.1 - 1.1e-64 217.2 0.0 1.6e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ26948.1 - 1e-09 37.5 0.7 5.5e-09 35.1 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RecA PF00154.16 CBZ26948.1 - 0.012 14.6 0.0 0.16 10.9 0.0 2.3 2 1 1 3 3 3 0 recA bacterial DNA recombination protein YadA_head PF05658.9 CBZ26948.1 - 0.42 10.9 4.7 1 9.6 0.6 2.3 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin Ribosomal_L32e PF01655.13 CBZ26950.1 - 1.7e-40 137.4 0.7 2.1e-40 137.1 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 PIG-S PF10510.4 CBZ26951.1 - 0.3 9.6 3.8 0.18 10.4 0.5 1.8 1 1 1 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein PEHE PF15275.1 CBZ26951.1 - 0.56 10.6 7.1 0.23 11.8 3.1 1.6 1 1 0 1 1 1 0 PEHE domain Wbp11 PF09429.5 CBZ26951.1 - 3.3 7.7 19.8 0.23 11.4 8.9 2.3 2 1 0 2 2 2 0 WW domain binding protein 11 PAP_assoc PF03828.14 CBZ26952.1 - 4.7e-05 23.2 0.6 0.00014 21.7 0.4 1.8 1 1 0 1 1 1 1 Cid1 family poly A polymerase SET PF00856.23 CBZ26953.1 - 1.5e-07 31.9 0.3 4e-05 23.9 0.1 2.7 2 1 0 2 2 2 1 SET domain PHD PF00628.24 CBZ26953.1 - 0.12 12.1 10.4 0.43 10.3 7.2 2.1 1 1 0 1 1 1 0 PHD-finger DUF2786 PF10979.3 CBZ26953.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) DKCLD PF08068.7 CBZ26954.1 - 4.7e-28 96.9 0.0 5e-27 93.5 0.0 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 CBZ26954.1 - 9e-23 81.0 2.5 1.2e-15 57.9 0.3 3.3 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CBZ26954.1 - 2.9e-20 71.7 0.9 5.7e-20 70.8 0.7 1.5 1 0 0 1 1 1 1 PUA domain ATP-synt PF00231.14 CBZ26955.1 - 3.9e-34 118.3 0.6 4.6e-34 118.1 0.4 1.1 1 0 0 1 1 1 1 ATP synthase Ribosomal_S6e PF01092.14 CBZ26956.1 - 8.5e-39 132.0 0.2 1.6e-38 131.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e WSK PF03832.8 CBZ26956.1 - 0.032 13.5 0.3 0.032 13.5 0.2 1.9 2 0 0 2 2 2 0 WSK motif RdRP_3 PF00998.18 CBZ26956.1 - 0.066 11.7 6.0 0.078 11.4 4.2 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase ATP-synt_C PF00137.16 CBZ26957.1 - 3.3e-25 87.7 26.7 1.3e-17 63.4 7.4 3.0 3 0 0 3 3 3 2 ATP synthase subunit C TF_Otx PF03529.8 CBZ26957.1 - 0.022 14.9 0.7 0.046 13.9 0.5 1.5 1 0 0 1 1 1 0 Otx1 transcription factor GerA PF03323.8 CBZ26957.1 - 0.18 9.8 3.4 1.8 6.6 0.3 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein ATP-synt_C PF00137.16 CBZ26958.1 - 3.3e-25 87.7 26.7 1.3e-17 63.4 7.4 3.0 3 0 0 3 3 3 2 ATP synthase subunit C TF_Otx PF03529.8 CBZ26958.1 - 0.022 14.9 0.7 0.046 13.9 0.5 1.5 1 0 0 1 1 1 0 Otx1 transcription factor GerA PF03323.8 CBZ26958.1 - 0.18 9.8 3.4 1.8 6.6 0.3 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Gaa1 PF04114.9 CBZ26959.1 - 1.9e-07 30.1 1.1 3.8e-07 29.1 0.7 1.5 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Ribosomal_L37ae PF01780.14 CBZ26960.1 - 2e-36 123.7 5.1 2.1e-36 123.6 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.17 CBZ26960.1 - 0.00075 19.1 2.1 0.0011 18.6 1.4 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 CBZ26960.1 - 0.024 14.1 1.2 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain UPF0547 PF10571.4 CBZ26960.1 - 0.046 13.4 1.1 7.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 NOB1_Zn_bind PF08772.6 CBZ26960.1 - 0.089 12.6 3.7 0.98 9.2 2.6 2.3 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Carla_C4 PF01623.12 CBZ26960.1 - 0.094 12.4 1.6 0.12 12.1 1.1 1.3 1 1 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Zn_Tnp_IS1595 PF12760.2 CBZ26960.1 - 0.12 12.2 2.5 0.18 11.6 1.7 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-C4_ClpX PF06689.8 CBZ26960.1 - 6.6 6.3 7.0 1.2 8.7 2.1 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger Proteasome PF00227.21 CBZ26961.1 - 2.5e-57 193.2 0.0 3.2e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ26961.1 - 3.1e-13 48.7 0.0 7.2e-13 47.5 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pex14_N PF04695.8 CBZ26962.1 - 2.1e-28 99.0 0.1 2.1e-28 99.0 0.1 3.5 2 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 CBZ26962.1 - 8.6e-05 22.2 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 IncA protein Rootletin PF15035.1 CBZ26962.1 - 9.5e-05 22.4 2.3 0.00016 21.6 1.6 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion ATG16 PF08614.6 CBZ26962.1 - 0.0014 18.4 0.2 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) LOH1CR12 PF10158.4 CBZ26962.1 - 0.0017 18.1 0.3 0.0028 17.4 0.2 1.2 1 0 0 1 1 1 1 Tumour suppressor protein HlyD_2 PF12700.2 CBZ26962.1 - 0.0036 16.5 0.1 0.0052 15.9 0.1 1.2 1 0 0 1 1 1 1 HlyD family secretion protein Macoilin PF09726.4 CBZ26962.1 - 0.0057 14.9 0.4 0.0081 14.5 0.3 1.1 1 0 0 1 1 1 1 Transmembrane protein HALZ PF02183.13 CBZ26962.1 - 0.01 15.5 4.5 0.25 11.1 0.1 2.4 2 1 0 2 2 2 0 Homeobox associated leucine zipper GAS PF13851.1 CBZ26962.1 - 0.011 14.9 4.5 0.017 14.3 3.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.6 CBZ26962.1 - 0.012 13.9 0.6 0.017 13.4 0.4 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ERM PF00769.14 CBZ26962.1 - 0.019 14.5 4.3 0.037 13.5 3.0 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Cast PF10174.4 CBZ26962.1 - 0.035 12.1 4.4 0.047 11.7 3.1 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone TMF_DNA_bd PF12329.3 CBZ26962.1 - 0.053 13.3 11.3 0.13 12.0 1.2 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.7 CBZ26962.1 - 0.053 13.3 0.8 0.09 12.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 CBZ26962.1 - 0.054 11.9 1.9 0.082 11.3 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Siah-Interact_N PF09032.6 CBZ26962.1 - 0.095 12.7 6.6 0.45 10.5 0.2 2.6 1 1 1 2 2 2 0 Siah interacting protein, N terminal DUF2968 PF11180.3 CBZ26962.1 - 0.098 12.0 5.2 0.25 10.7 3.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TMCO5 PF14992.1 CBZ26962.1 - 0.12 11.5 3.3 0.17 10.9 2.3 1.1 1 0 0 1 1 1 0 TMCO5 family AAA_13 PF13166.1 CBZ26962.1 - 0.17 10.3 2.4 0.23 9.8 1.7 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 CBZ26962.1 - 0.25 9.1 0.3 0.34 8.7 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MbeD_MobD PF04899.7 CBZ26962.1 - 0.27 11.1 1.2 0.63 9.9 0.8 1.7 1 1 0 1 1 1 0 MbeD/MobD like APG6 PF04111.7 CBZ26962.1 - 0.41 9.6 4.6 0.59 9.1 3.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ALIX_LYPXL_bnd PF13949.1 CBZ26962.1 - 0.49 9.2 7.1 1.7 7.5 4.9 1.8 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV Not3 PF04065.10 CBZ26962.1 - 0.61 9.3 4.7 13 4.9 3.3 2.0 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component FlxA PF14282.1 CBZ26962.1 - 0.66 9.9 7.4 5.7 6.9 5.3 2.2 1 1 0 1 1 1 0 FlxA-like protein DUF4140 PF13600.1 CBZ26962.1 - 0.97 9.9 10.6 0.6 10.5 1.9 2.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) bZIP_1 PF00170.16 CBZ26962.1 - 1.2 9.1 7.8 0.68 9.9 0.5 2.4 1 1 1 2 2 2 0 bZIP transcription factor Mnd1 PF03962.10 CBZ26962.1 - 1.5 8.4 7.7 2.1 7.9 5.4 1.2 1 0 0 1 1 1 0 Mnd1 family WXG100 PF06013.7 CBZ26962.1 - 1.6 8.7 5.4 2 8.4 0.8 2.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG DivIC PF04977.10 CBZ26962.1 - 1.9 8.0 11.0 0.12 11.8 2.0 2.2 1 1 1 2 2 2 0 Septum formation initiator ADIP PF11559.3 CBZ26962.1 - 2.6 7.9 9.4 8.5 6.2 6.5 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 CBZ26962.1 - 3.3 8.0 4.3 21 5.5 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Atg14 PF10186.4 CBZ26962.1 - 6.5 5.6 7.5 11 4.8 5.0 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 CBZ26963.1 - 0.00096 19.1 2.5 0.0023 17.8 1.7 1.7 1 1 0 1 1 1 1 Outer membrane protein (OmpH-like) BolA PF01722.13 CBZ26964.1 - 4.7e-20 71.3 0.0 5.3e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Tubulin PF00091.20 CBZ26965.1 - 7.4e-70 235.1 0.0 1.2e-69 234.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ26965.1 - 6.4e-48 161.9 0.1 9.7e-48 161.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBZ26965.1 - 2.7e-05 24.2 0.0 6.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBZ26965.1 - 0.0076 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Hist_deacetyl PF00850.14 CBZ26966.1 - 2.3e-78 263.6 0.5 2.9e-46 158.1 0.4 2.2 2 0 0 2 2 2 2 Histone deacetylase domain RAP1 PF07218.6 CBZ26966.1 - 0.98 7.4 3.5 1.4 6.9 2.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CLN3 PF02487.12 CBZ26967.1 - 1e-28 100.2 35.1 1.8e-14 53.3 8.2 3.2 2 1 1 3 3 3 3 CLN3 protein Cyt-b5 PF00173.23 CBZ26968.1 - 9.8e-05 22.0 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1583 PF07622.6 CBZ26968.1 - 0.029 12.8 0.1 0.042 12.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1583) Ribosomal_L5_C PF00673.16 CBZ26970.1 - 2.5e-22 78.4 0.0 4.1e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CBZ26970.1 - 9.2e-17 60.5 0.4 3.2e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L5 SET PF00856.23 CBZ26971.1 - 7.7e-05 23.0 0.0 0.00017 21.9 0.0 1.8 1 1 0 1 1 1 1 SET domain Pepsin-I3 PF06394.8 CBZ26972.1 - 0.3 10.7 3.5 0.39 10.4 0.4 2.7 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain R3H PF01424.17 CBZ26973.1 - 1.4e-10 40.6 0.0 2.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 CBZ26973.1 - 1.5e-07 31.2 225.9 0.00012 21.9 9.8 14.8 15 1 0 15 15 15 8 NF-X1 type zinc finger Pox_F17 PF04767.7 CBZ26974.1 - 0.053 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein An_peroxidase PF03098.10 CBZ26974.1 - 0.1 10.9 0.0 0.22 9.8 0.0 1.4 2 0 0 2 2 2 0 Animal haem peroxidase Shufflon_N PF04917.7 CBZ26974.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region CTDII PF01556.13 CBZ26975.1 - 3.7e-22 77.9 0.1 1.2e-20 73.1 0.0 2.9 4 0 0 4 4 4 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBZ26975.1 - 9.2e-14 51.2 13.9 1.6e-13 50.4 9.0 1.9 2 1 0 2 2 2 1 DnaJ central domain HypA PF01155.14 CBZ26975.1 - 0.00084 19.0 6.7 0.073 12.7 1.3 2.6 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family CART PF06373.6 CBZ26975.1 - 0.023 14.6 0.6 0.08 12.9 0.4 2.0 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) Lar_restr_allev PF14354.1 CBZ26975.1 - 0.042 14.1 5.2 0.16 12.2 0.9 3.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar DUF2777 PF10949.3 CBZ26975.1 - 0.12 11.9 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) PAAR_motif PF05488.8 CBZ26975.1 - 0.31 11.0 4.5 26 4.9 0.0 2.7 2 1 0 2 2 2 0 PAAR motif ZZ PF00569.12 CBZ26975.1 - 0.39 10.2 3.6 2.4 7.7 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type DZR PF12773.2 CBZ26975.1 - 1.3 8.9 8.2 1.5 8.6 0.6 2.6 1 1 1 2 2 2 0 Double zinc ribbon Pox_MCEL PF03291.11 CBZ26976.1 - 5.5e-43 147.0 0.0 6.4e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme mRNA_cap_C PF03919.10 CBZ26976.1 - 4.5e-07 30.1 0.0 1.5e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain mRNA_cap_enzyme PF01331.14 CBZ26976.1 - 9.4e-07 28.7 0.0 0.012 15.2 0.0 2.5 2 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain Methyltransf_18 PF12847.2 CBZ26976.1 - 0.00017 22.1 0.0 0.00093 19.7 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ26976.1 - 0.003 17.9 0.1 0.01 16.1 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ26976.1 - 0.0044 17.0 0.0 0.0044 17.0 0.0 3.3 3 1 0 3 3 3 1 Methyltransferase domain NUP PF06516.6 CBZ26976.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) Methyltransf_31 PF13847.1 CBZ26976.1 - 0.04 13.5 0.0 0.085 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GATase PF00117.23 CBZ26978.1 - 6.1e-39 133.4 0.0 1.1e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 CBZ26978.1 - 1.6e-28 98.2 0.4 1.7e-27 94.9 0.3 2.6 1 1 0 1 1 1 1 GMP synthase C terminal domain Peptidase_C26 PF07722.8 CBZ26978.1 - 1.5e-15 57.2 0.0 9.4e-15 54.6 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 CBZ26978.1 - 2.3e-09 36.4 0.1 0.00011 21.1 0.0 2.4 2 0 0 2 2 2 2 NAD synthase QueC PF06508.8 CBZ26978.1 - 3e-05 23.3 0.0 0.00015 21.1 0.0 2.0 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 CBZ26978.1 - 0.001 18.6 0.1 0.002 17.7 0.1 1.4 1 0 0 1 1 1 1 Asparagine synthase GATase_3 PF07685.9 CBZ26978.1 - 0.0012 18.4 0.1 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Arginosuc_synth PF00764.14 CBZ26978.1 - 0.0015 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase ThiI PF02568.9 CBZ26978.1 - 0.0023 17.4 0.1 0.0097 15.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 CBZ26978.1 - 0.0026 17.5 0.0 0.0046 16.8 0.0 1.5 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 CBZ26978.1 - 0.0056 16.1 0.1 0.028 13.9 0.1 2.0 2 0 0 2 2 2 1 PP-loop family tRNA_Me_trans PF03054.11 CBZ26978.1 - 0.012 14.2 0.1 0.044 12.3 0.1 1.8 2 0 0 2 2 2 0 tRNA methyl transferase Tup_N PF08581.5 CBZ26979.1 - 0.004 17.3 0.8 0.004 17.3 0.5 3.2 2 2 2 4 4 4 1 Tup N-terminal Med20 PF08612.6 CBZ26979.1 - 0.036 13.2 1.3 0.053 12.6 0.4 1.5 1 1 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF4206 PF13901.1 CBZ26979.1 - 0.13 11.8 0.9 0.25 10.8 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) AKNA PF12443.3 CBZ26979.1 - 0.14 12.1 16.0 0.046 13.7 4.8 2.6 2 1 1 3 3 2 0 AT-hook-containing transcription factor FlaC_arch PF05377.6 CBZ26979.1 - 0.26 11.2 5.1 9 6.2 0.7 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 CBZ26979.1 - 0.46 10.3 5.1 9.7 6.1 0.1 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3584 PF12128.3 CBZ26979.1 - 0.5 7.6 32.6 0.61 7.3 22.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 CBZ26979.1 - 0.73 9.3 32.1 0.3 10.6 9.1 2.5 1 1 1 2 2 2 0 IncA protein MAP7 PF05672.6 CBZ26979.1 - 1 8.6 37.5 0.3 10.4 19.9 2.2 1 1 1 2 2 2 0 MAP7 (E-MAP-115) family Hom_end_hint PF05203.11 CBZ26979.1 - 2.2 7.9 12.7 1.7 8.3 7.8 1.4 1 1 0 1 1 1 0 Hom_end-associated Hint Bacillus_HBL PF05791.6 CBZ26979.1 - 2.9 7.2 10.5 0.87 8.9 2.9 2.4 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Lectin_N PF03954.9 CBZ26979.1 - 3.6 6.9 7.3 0.76 9.1 1.4 2.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.7 CBZ26979.1 - 3.6 7.3 11.6 0.4 10.4 3.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Atg14 PF10186.4 CBZ26979.1 - 3.7 6.4 31.9 0.12 11.3 16.0 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PLRV_ORF5 PF01690.12 CBZ26979.1 - 5.2 6.1 12.8 6.3 5.8 8.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein BAG PF02179.11 CBZ26981.1 - 8.2e-05 22.6 0.2 0.00015 21.8 0.1 1.3 1 0 0 1 1 1 1 BAG domain DUF2036 PF09724.4 CBZ26982.1 - 1.2e-30 106.8 0.0 1.8e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) zf-CCCH PF00642.19 CBZ26983.1 - 1.6e-06 27.6 14.9 1.9e-05 24.1 1.1 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ26983.1 - 0.0083 16.0 5.9 0.66 10.0 0.2 2.9 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type LRV_FeS PF05484.6 CBZ26983.1 - 0.097 12.2 0.3 0.097 12.2 0.2 2.7 3 0 0 3 3 3 0 LRV protein FeS4 cluster DUF883 PF05957.8 CBZ26985.1 - 0.00036 20.8 15.8 0.0086 16.4 4.8 3.5 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 CBZ26985.1 - 0.0018 17.8 10.6 0.0018 17.8 7.3 2.1 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain RmuC PF02646.11 CBZ26985.1 - 0.006 15.4 2.0 0.006 15.4 1.4 2.7 2 1 1 3 3 3 1 RmuC family DUF4239 PF14023.1 CBZ26985.1 - 0.021 14.2 0.6 0.021 14.2 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4239) DUF357 PF04010.8 CBZ26985.1 - 0.034 13.8 0.9 1.5 8.5 0.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF357) ZYG-11_interact PF05884.7 CBZ26985.1 - 0.035 13.1 7.5 1.7 7.6 5.2 2.2 1 1 0 1 1 1 0 Interactor of ZYG-11 Dicistro_VP4 PF11492.3 CBZ26985.1 - 0.048 13.6 2.7 3.7 7.6 0.1 3.1 3 0 0 3 3 3 0 Cricket paralysis virus, VP4 ApoO PF09769.4 CBZ26985.1 - 0.049 13.3 6.0 0.089 12.5 1.1 2.6 1 1 1 2 2 2 0 Apolipoprotein O dUTPase_2 PF08761.6 CBZ26985.1 - 0.053 13.6 3.0 0.045 13.8 1.0 1.7 1 1 1 2 2 2 0 dUTPase Filament PF00038.16 CBZ26985.1 - 0.37 10.2 6.3 3.9 6.8 0.2 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF1451 PF07295.6 CBZ26985.1 - 0.89 9.3 3.5 6.6 6.5 0.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1451) ATP-synt_B PF00430.13 CBZ26985.1 - 1.1 9.0 17.4 0.14 11.9 1.8 2.8 2 1 1 3 3 3 0 ATP synthase B/B' CF(0) ATG_C PF09333.6 CBZ26985.1 - 1.1 9.4 15.8 44 4.3 0.2 3.6 1 1 1 2 2 2 0 ATG C terminal domain ERp29 PF07749.7 CBZ26985.1 - 2.9 8.6 7.9 3.6 8.2 1.4 2.8 1 1 1 2 2 2 0 Endoplasmic reticulum protein ERp29, C-terminal domain Phasin PF05597.6 CBZ26985.1 - 6.5 6.5 17.1 2.7 7.7 1.6 3.3 1 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) YtxH PF12732.2 CBZ26985.1 - 8.3 6.8 13.5 2.1e+03 -0.9 9.3 3.2 1 1 0 1 1 1 0 YtxH-like protein zf-C3HC4 PF00097.20 CBZ26986.1 - 0.00084 18.9 12.9 0.00084 18.9 9.0 2.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ26986.1 - 0.023 14.7 17.7 0.023 14.7 12.2 2.8 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBZ26986.1 - 0.068 12.9 14.0 0.16 11.7 9.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBZ26986.1 - 0.22 11.2 8.5 0.9 9.3 5.9 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 CBZ26986.1 - 0.47 10.2 23.6 0.048 13.4 12.7 2.2 2 0 0 2 2 2 0 zinc-RING finger domain DUF1736 PF08409.6 CBZ26988.1 - 6.2e-21 73.7 0.4 1.8e-20 72.2 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_11 PF13414.1 CBZ26988.1 - 5.3e-05 22.7 2.3 0.0076 15.8 0.4 2.7 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 CBZ26988.1 - 0.0025 17.8 0.4 0.22 11.8 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Aa_trans PF01490.13 CBZ26989.1 - 4.6e-60 203.2 32.6 5.4e-60 202.9 22.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ26989.1 - 2e-06 26.9 10.0 2e-06 26.9 6.9 2.1 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2937 PF11157.3 CBZ26989.1 - 0.13 11.5 1.0 3.9 6.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Y_phosphatase3 PF13350.1 CBZ26991.1 - 2.4e-39 135.1 0.0 3.1e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 CBZ26991.1 - 1.6e-11 44.0 0.2 4.8e-11 42.6 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 CBZ26991.1 - 0.003 16.9 0.0 0.0083 15.5 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBZ26991.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 CBZ26991.1 - 0.026 13.8 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 CBZ26991.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.5 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain TRAP_alpha PF03896.11 CBZ26992.1 - 6.1e-14 51.6 0.0 7.8e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Wzt_C PF14524.1 CBZ26992.1 - 0.078 12.6 0.0 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 Wzt C-terminal domain zf-Tim10_DDP PF02953.10 CBZ26993.1 - 4.3e-13 48.3 3.3 4.5e-13 48.2 2.3 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CBZ26993.1 - 0.0088 15.5 2.2 0.011 15.2 1.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Mito_carr PF00153.22 CBZ26996.1 - 8.1e-10 38.2 0.1 1e-07 31.5 0.0 3.3 3 0 0 3 3 3 1 Mitochondrial carrier protein VEK-30 PF12107.3 CBZ26997.1 - 0.16 11.6 3.3 0.62 9.8 2.3 2.0 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway Carn_acyltransf PF00755.15 CBZ26998.1 - 2.4e-70 237.2 0.0 6.5e-70 235.8 0.0 1.7 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase SEP PF08059.8 CBZ26999.1 - 3.1e-18 65.8 0.2 1.2e-17 63.9 0.0 2.1 2 1 1 3 3 3 1 SEP domain CUE PF02845.11 CBZ26999.1 - 0.00078 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 CBZ26999.1 - 0.012 15.1 0.1 0.03 13.8 0.1 1.7 1 0 0 1 1 1 0 UBA-like domain THF_DHG_CYH_C PF02882.14 CBZ27001.1 - 1.4e-31 108.7 0.5 1.4e-29 102.2 0.3 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CBZ27001.1 - 1.9e-29 102.1 0.0 2.7e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF463 PF04317.7 CBZ27001.1 - 0.042 12.4 0.0 0.062 11.8 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 APG6 PF04111.7 CBZ27002.1 - 0.043 12.8 1.5 0.056 12.4 1.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4329 PF14220.1 CBZ27002.1 - 0.068 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) Spc24 PF08286.6 CBZ27002.1 - 0.18 11.5 1.3 0.88 9.2 0.9 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Macoilin PF09726.4 CBZ27002.1 - 0.28 9.4 3.1 0.36 9.0 2.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Nup54 PF13874.1 CBZ27002.1 - 0.72 9.5 6.9 1.5 8.5 4.1 1.8 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 MscS_porin PF12795.2 CBZ27002.1 - 0.87 8.8 10.9 1.3 8.2 7.5 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain OPA3 PF07047.7 CBZ27003.1 - 0.00029 20.6 3.0 0.00049 19.8 2.1 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DNA_primase_S PF01896.14 CBZ27006.1 - 5.9e-39 133.1 0.1 9e-39 132.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit cNMP_binding PF00027.24 CBZ27007.1 - 2.8e-05 23.8 0.0 0.023 14.4 0.0 3.6 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain GCC2_GCC3 PF07699.8 CBZ27008.1 - 0.00027 20.4 4.1 0.00027 20.4 2.9 9.1 6 3 3 9 9 9 4 GCC2 and GCC3 NCD3G PF07562.9 CBZ27008.1 - 0.31 10.7 48.8 0.046 13.4 0.9 8.1 8 1 0 8 8 8 0 Nine Cysteines Domain of family 3 GPCR Serglycin PF04360.7 CBZ27008.1 - 0.93 9.2 7.8 2.8 7.6 5.4 1.8 1 0 0 1 1 1 0 Serglycin Ribosomal_S19 PF00203.16 CBZ27009.1 - 5.6e-27 93.1 0.2 9.8e-27 92.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.11 CBZ27009.1 - 0.0049 16.1 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase FlaC_arch PF05377.6 CBZ27010.1 - 0.057 13.3 0.4 0.44 10.4 0.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Acetyltransf_1 PF00583.19 CBZ27011.1 - 3.9e-13 49.2 0.0 6.5e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ27011.1 - 8.8e-07 29.0 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBZ27011.1 - 9.7e-05 22.0 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CBZ27011.1 - 0.00026 21.0 0.0 0.00087 19.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CBZ27011.1 - 0.029 14.2 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CBZ27011.1 - 0.099 12.8 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S19 PF00203.16 CBZ27012.1 - 5.6e-27 93.1 0.2 9.8e-27 92.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.11 CBZ27012.1 - 0.0049 16.1 0.0 0.0054 16.0 0.0 1.2 1 0 0 1 1 1 1 Putative modulator of DNA gyrase tRNA_bind PF01588.15 CBZ27013.1 - 9.4e-27 92.7 0.0 2.4e-26 91.3 0.0 1.7 2 0 0 2 2 2 1 Putative tRNA binding domain PNGaseA PF12222.3 CBZ27013.1 - 0.14 10.9 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Dynamin_N PF00350.18 CBZ27014.1 - 5.5e-15 55.5 0.0 1.9e-14 53.8 0.0 1.9 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CBZ27014.1 - 6.3e-11 42.2 0.0 1.7e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ27014.1 - 0.00081 18.6 0.1 0.26 10.5 0.0 2.7 3 0 0 3 3 3 2 Ferrous iron transport protein B DUF258 PF03193.11 CBZ27014.1 - 0.0027 16.9 0.2 0.013 14.6 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CBZ27014.1 - 0.0068 16.8 0.0 0.29 11.6 0.0 2.5 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBZ27014.1 - 0.017 14.5 0.1 1.2 8.5 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Lysine_decarbox PF03641.9 CBZ27014.1 - 0.025 14.4 0.0 0.069 12.9 0.0 1.6 1 1 0 1 1 1 0 Possible lysine decarboxylase Nup153 PF08604.5 CBZ27014.1 - 0.027 13.1 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup153-like ABC_tran PF00005.22 CBZ27014.1 - 0.062 13.5 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.15 CBZ27014.1 - 0.12 11.0 0.2 7.1 5.1 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Pkinase PF00069.20 CBZ27015.1 - 3.9e-45 154.0 0.0 6.5e-36 123.8 0.0 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27015.1 - 9.7e-18 64.1 0.0 3.2e-15 55.9 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.9 CBZ27015.1 - 0.00011 21.3 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ27015.1 - 0.00012 21.8 0.2 0.00023 20.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ27015.1 - 0.048 12.6 0.0 0.19 10.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.15 CBZ27015.1 - 0.048 13.2 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Med26 PF08711.6 CBZ27016.1 - 2e-06 27.1 5.6 1.3e-05 24.5 0.0 3.2 3 0 0 3 3 3 2 TFIIS helical bundle-like domain DUF727 PF05303.7 CBZ27016.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF727) RabGAP-TBC PF00566.13 CBZ27018.1 - 1.7e-33 115.9 0.0 2.6e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FHA PF00498.21 CBZ27019.1 - 1.3e-14 54.0 0.0 2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 FHA domain Rotamase PF00639.16 CBZ27019.1 - 1.1e-12 48.5 0.0 5.3e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CBZ27019.1 - 4.5e-08 33.3 0.0 1.3e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CBZ27019.1 - 0.00013 22.5 2.0 0.00054 20.5 0.0 2.6 3 0 0 3 3 3 1 PPIC-type PPIASE domain PPR PF01535.15 CBZ27020.1 - 0.0039 17.0 0.0 15 5.8 0.0 4.4 4 0 0 4 4 4 1 PPR repeat TPR_14 PF13428.1 CBZ27020.1 - 0.2 12.3 6.1 40 5.2 0.2 5.1 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ27020.1 - 0.41 11.2 5.9 0.43 11.1 2.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ27020.1 - 0.92 10.2 10.3 0.12 13.1 2.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat Kinesin PF00225.18 CBZ27021.1 - 7.4e-87 291.1 0.1 8.5e-48 162.7 0.0 2.5 2 0 0 2 2 2 2 Kinesin motor domain AAA_33 PF13671.1 CBZ27021.1 - 0.0049 16.7 0.3 0.045 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain TPR_MLP1_2 PF07926.7 CBZ27021.1 - 0.009 15.7 15.1 0.009 15.7 10.5 4.2 4 1 1 5 5 5 2 TPR/MLP1/MLP2-like protein CCDC155 PF14662.1 CBZ27021.1 - 6.8 6.2 39.0 0.46 10.0 10.8 3.8 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 AAA PF00004.24 CBZ27022.1 - 1.3e-43 148.3 0.1 3e-43 147.1 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ27022.1 - 7.1e-07 29.4 0.0 0.00056 20.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_5 PF07728.9 CBZ27022.1 - 1.5e-06 28.0 0.1 3.2e-05 23.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBZ27022.1 - 1.7e-05 24.8 0.0 4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CBZ27022.1 - 1.9e-05 24.7 0.0 8.4e-05 22.6 0.0 1.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 CBZ27022.1 - 0.0001 23.1 0.7 0.00029 21.6 0.1 2.2 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 CBZ27022.1 - 0.00018 20.5 0.0 0.00033 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CBZ27022.1 - 0.00033 19.7 0.0 0.00064 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Arch_ATPase PF01637.13 CBZ27022.1 - 0.00057 19.6 0.1 0.27 10.9 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase AAA_19 PF13245.1 CBZ27022.1 - 0.0007 19.3 0.1 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CBZ27022.1 - 0.0011 18.8 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ27022.1 - 0.0013 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ27022.1 - 0.0024 17.0 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 CBZ27022.1 - 0.0024 17.7 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBZ27022.1 - 0.0029 17.0 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CBZ27022.1 - 0.007 16.5 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 CBZ27022.1 - 0.0072 15.5 0.0 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CBZ27022.1 - 0.0083 15.7 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ27022.1 - 0.0085 16.3 0.4 0.022 15.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CBZ27022.1 - 0.0089 15.6 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 CBZ27022.1 - 0.0092 14.7 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Histone PF00125.19 CBZ27022.1 - 0.019 15.0 0.1 0.085 12.9 0.0 2.2 2 0 0 2 2 1 0 Core histone H2A/H2B/H3/H4 AAA_25 PF13481.1 CBZ27022.1 - 0.023 14.1 0.8 0.14 11.5 0.1 2.1 1 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CBZ27022.1 - 0.031 14.0 0.1 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.21 CBZ27022.1 - 0.049 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain PhoH PF02562.11 CBZ27022.1 - 0.063 12.4 0.2 0.15 11.2 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 CBZ27022.1 - 0.066 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 CBZ27022.1 - 0.089 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Rer1 PF03248.8 CBZ27023.1 - 8.1e-59 198.1 2.8 1e-58 197.8 1.9 1.0 1 0 0 1 1 1 1 Rer1 family DmsC PF04976.7 CBZ27023.1 - 0.011 15.0 0.4 0.016 14.5 0.3 1.3 1 1 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) UPF0066 PF01980.11 CBZ27024.1 - 1.3e-27 96.1 0.0 1e-23 83.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family UPF0066 PWWP PF00855.12 CBZ27024.1 - 1.1e-05 25.5 0.0 3.4e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 PWWP domain Acetyltransf_3 PF13302.1 CBZ27025.1 - 9.1e-12 45.3 0.0 1.3e-06 28.6 0.0 2.7 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBZ27025.1 - 8e-05 22.5 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CBZ27025.1 - 0.00062 19.6 0.0 0.0082 16.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBZ27025.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein SARA PF11409.3 CBZ27025.1 - 0.14 12.0 1.8 0.71 9.8 0.1 2.7 2 0 0 2 2 2 0 Smad anchor for receptor activation (SARA) Acetyltransf_4 PF13420.1 CBZ27025.1 - 0.16 11.8 0.0 0.92 9.4 0.0 2.1 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain UQ_con PF00179.21 CBZ27026.1 - 3e-42 143.3 0.0 3.8e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ27026.1 - 7.9e-06 25.6 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CBZ27026.1 - 0.029 14.2 0.0 0.089 12.6 0.0 1.5 1 1 0 1 1 1 0 RWD domain AAA PF00004.24 CBZ27027.1 - 2.5e-38 131.2 0.0 7.9e-38 129.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ27027.1 - 1.9e-05 24.4 0.1 0.00017 21.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ27027.1 - 3.9e-05 23.7 1.6 0.0085 16.0 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 CBZ27027.1 - 0.00033 19.7 0.0 0.001 18.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CBZ27027.1 - 0.00034 20.5 0.1 0.0033 17.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 CBZ27027.1 - 0.0015 17.4 0.3 0.0034 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 CBZ27027.1 - 0.0019 18.3 2.2 0.053 13.6 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 CBZ27027.1 - 0.0036 17.1 0.3 0.041 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ27027.1 - 0.0067 16.1 0.2 0.02 14.6 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 CBZ27027.1 - 0.0067 15.6 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CBZ27027.1 - 0.014 14.5 1.3 0.017 14.2 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 CBZ27027.1 - 0.02 14.3 0.7 0.041 13.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 CBZ27027.1 - 0.029 13.7 4.2 0.036 13.4 0.2 2.5 2 1 0 3 3 3 0 AAA domain AAA_17 PF13207.1 CBZ27027.1 - 0.042 14.6 2.3 0.13 13.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 CBZ27027.1 - 0.047 12.8 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 CBZ27027.1 - 0.049 12.8 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 CBZ27027.1 - 0.061 12.9 0.2 0.64 9.6 0.0 2.4 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 CBZ27027.1 - 0.067 12.6 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 CBZ27027.1 - 0.083 12.4 0.1 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Armet PF10208.4 CBZ27030.1 - 0.039 13.6 0.0 0.95 9.1 0.0 2.2 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding HeH PF12949.2 CBZ27030.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain Prefoldin PF02996.12 CBZ27032.1 - 4.5e-19 68.2 2.0 6.9e-19 67.6 0.7 1.6 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 CBZ27032.1 - 0.0027 17.4 1.0 0.025 14.3 0.5 2.1 2 0 0 2 2 2 1 Prefoldin subunit THF_DHG_CYH_C PF02882.14 CBZ27032.1 - 0.039 13.0 0.1 0.071 12.1 0.1 1.5 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sec20 PF03908.8 CBZ27032.1 - 0.2 11.3 1.7 20 4.9 1.1 2.4 3 0 0 3 3 3 0 Sec20 DUF1454 PF07305.7 CBZ27033.1 - 0.026 13.6 0.0 0.044 12.8 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1454) Herpes_gE PF02480.11 CBZ27034.1 - 0.0056 14.9 0.4 0.011 14.0 0.0 1.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Vpu PF00558.14 CBZ27034.1 - 0.19 11.2 0.2 0.46 10.0 0.1 1.5 1 0 0 1 1 1 0 Vpu protein Herpes_US9 PF06072.6 CBZ27034.1 - 9.2 6.1 7.1 3.5 7.5 0.0 3.0 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 PMG PF05287.7 CBZ27035.1 - 8.5e-25 87.6 110.2 0.00054 19.8 5.9 10.3 1 1 9 10 10 10 10 PMG protein Pentapeptide_2 PF01469.13 CBZ27035.1 - 0.0032 17.0 0.0 26 4.5 0.0 4.6 4 1 1 5 5 5 2 Pentapeptide repeats (8 copies) PMG PF05287.7 CBZ27036.1 - 3.2e-44 150.8 152.8 4.9e-05 23.2 5.5 12.9 1 1 12 13 13 13 13 PMG protein Pentapeptide_2 PF01469.13 CBZ27036.1 - 1.9e-07 30.6 0.0 39 4.0 0.0 8.4 8 0 0 8 8 8 2 Pentapeptide repeats (8 copies) YbaB_DNA_bd PF02575.11 CBZ27038.1 - 3.7e-05 23.5 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family HIF-1 PF11413.3 CBZ27038.1 - 0.022 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 MMR_HSR1 PF01926.18 CBZ27039.1 - 2.1e-15 56.6 0.0 1.8e-14 53.6 0.0 2.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBZ27039.1 - 5.8e-07 29.4 0.0 7e-05 22.7 0.0 2.4 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 CBZ27039.1 - 1.8e-05 24.2 0.0 0.00013 21.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBZ27039.1 - 0.023 13.8 0.0 0.05 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 CBZ27039.1 - 0.047 14.1 0.0 0.19 12.2 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein Septin PF00735.13 CBZ27039.1 - 0.078 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 CBZ27039.1 - 0.082 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 CBZ27039.1 - 0.1 12.0 0.0 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 CBZ27039.1 - 0.27 10.5 0.0 0.7 9.1 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AIG1 PF04548.11 CBZ27039.1 - 0.38 9.8 0.0 1.3 8.0 0.0 1.8 1 1 0 1 1 1 0 AIG1 family Sec34 PF04136.10 CBZ27040.1 - 0.006 16.2 1.9 0.006 16.2 1.3 2.6 3 0 0 3 3 3 1 Sec34-like family AAA_23 PF13476.1 CBZ27040.1 - 0.24 11.6 5.2 1.6 9.0 1.5 2.3 2 0 0 2 2 2 0 AAA domain UBN2 PF14223.1 CBZ27040.1 - 0.73 9.6 10.1 13 5.6 3.6 3.0 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type zf-CCCH PF00642.19 CBZ27041.1 - 0.0039 16.8 0.9 0.0039 16.8 0.6 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ27041.1 - 1.7 8.7 8.8 0.54 10.3 0.6 3.3 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 CBZ27042.1 - 0.00098 18.7 1.0 0.00098 18.7 0.7 3.6 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FAD_binding_6 PF00970.19 CBZ27044.1 - 1.1e-24 86.4 0.0 2e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CBZ27044.1 - 5.1e-24 84.9 0.0 7.6e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CBZ27044.1 - 1.1e-05 25.4 0.1 0.0011 18.8 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CBZ27044.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain GreA_GreB PF01272.14 CBZ27044.1 - 0.16 11.6 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term NAD_binding_1 PF00175.16 CBZ27045.1 - 2.9e-25 88.9 0.0 4.3e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBZ27045.1 - 2.6e-19 69.1 0.0 4e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CBZ27045.1 - 3.4e-07 30.2 0.0 1.9e-06 27.8 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SUI1 PF01253.17 CBZ27046.1 - 6.2e-11 41.9 0.0 1.6e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 CBZ27046.1 - 0.1 12.3 0.0 0.29 10.8 0.0 1.8 1 0 0 1 1 1 0 PUA domain DUF2296 PF10058.4 CBZ27047.1 - 0.0091 15.7 13.6 0.045 13.5 0.2 3.3 3 1 0 3 3 3 2 Predicted integral membrane metal-binding protein (DUF2296) Rpr2 PF04032.11 CBZ27047.1 - 0.03 14.1 0.5 0.03 14.1 0.4 3.1 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF4428 PF14471.1 CBZ27047.1 - 0.18 11.5 0.3 0.18 11.5 0.2 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4428) CCDC50_N PF15295.1 CBZ27047.1 - 0.2 11.6 2.2 3.9 7.4 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus Mu-like_Com PF10122.4 CBZ27047.1 - 0.23 10.5 16.6 0.085 11.9 0.5 4.7 3 2 1 4 4 4 0 Mu-like prophage protein Com Cytochrome_C7 PF14522.1 CBZ27047.1 - 0.47 10.1 12.4 0.14 11.7 3.0 2.9 1 1 1 2 2 2 0 Cytochrome c7 DZR PF12773.2 CBZ27047.1 - 0.71 9.7 12.8 8.3 6.3 3.2 3.9 1 1 2 3 3 3 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.6 CBZ27047.1 - 0.88 9.2 12.2 0.13 11.9 0.4 3.6 4 1 0 4 4 4 0 Putative transposase DNA-binding domain DUF3133 PF11331.3 CBZ27047.1 - 1.4 8.5 21.7 0.15 11.6 2.4 4.8 3 2 2 5 5 5 0 Protein of unknown function (DUF3133) Cytochrom_c3_2 PF14537.1 CBZ27047.1 - 2.1 8.7 16.5 0.15 12.3 5.4 2.7 2 1 1 3 3 3 0 Cytochrome c3 DNA_RNApol_7kD PF03604.8 CBZ27047.1 - 9.1 5.8 16.1 36 3.9 0.0 5.3 5 1 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit Pkinase PF00069.20 CBZ27048.1 - 2.1e-65 220.4 0.0 2.6e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27048.1 - 2.3e-33 115.3 0.0 3e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ27048.1 - 4.9e-06 25.7 0.0 6.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBZ27048.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ27048.1 - 0.064 12.9 0.1 0.47 10.1 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family MMR_HSR1 PF01926.18 CBZ27049.1 - 2.1e-15 56.6 0.0 1.4e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBZ27049.1 - 3.7e-07 30.1 0.0 5.5e-05 23.0 0.0 2.4 1 1 1 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 CBZ27049.1 - 1.1e-05 24.9 0.0 9.7e-05 21.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBZ27049.1 - 0.019 14.1 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Miro PF08477.8 CBZ27049.1 - 0.033 14.7 0.0 0.15 12.5 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein Septin PF00735.13 CBZ27049.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 CBZ27049.1 - 0.066 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 CBZ27049.1 - 0.068 12.6 0.0 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 CBZ27049.1 - 0.19 10.9 0.0 0.56 9.4 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AIG1 PF04548.11 CBZ27049.1 - 0.26 10.3 0.0 1 8.4 0.0 1.9 1 1 0 1 1 1 0 AIG1 family Herpes_gE PF02480.11 CBZ27050.1 - 0.0056 14.9 0.4 0.011 14.0 0.0 1.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E Vpu PF00558.14 CBZ27050.1 - 0.19 11.2 0.2 0.46 10.0 0.1 1.5 1 0 0 1 1 1 0 Vpu protein Herpes_US9 PF06072.6 CBZ27050.1 - 9.2 6.1 7.1 3.5 7.5 0.0 3.0 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF3184 PF11380.3 CBZ27051.1 - 1.2e-95 320.9 20.7 7.4e-53 179.5 5.8 5.0 3 1 1 4 4 4 4 Protein of unknown function (DUF3184) Ribosomal_L22 PF00237.14 CBZ27052.1 - 8.8e-13 48.1 0.0 1.2e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e IQ PF00612.22 CBZ27055.1 - 0.019 14.5 2.4 0.055 13.1 1.7 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Prp18 PF02840.10 CBZ27056.1 - 2.4e-10 40.4 0.1 2.4e-10 40.4 0.1 2.1 3 0 0 3 3 3 1 Prp18 domain Macoilin PF09726.4 CBZ27056.1 - 9.4 4.3 9.4 13 3.8 6.5 1.2 1 0 0 1 1 1 0 Transmembrane protein EF-hand_7 PF13499.1 CBZ27057.1 - 9.4e-11 41.6 0.1 3.1e-05 23.9 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ27057.1 - 9.5e-10 37.5 0.3 1.8 8.6 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CBZ27057.1 - 2.8e-06 26.8 0.0 0.2 11.2 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ27057.1 - 1.1e-05 24.4 0.0 0.87 9.0 0.0 4.2 4 0 0 4 4 4 2 EF hand RseA_N PF03872.8 CBZ27057.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain AAA PF00004.24 CBZ27058.1 - 1.5e-13 51.0 0.0 1.4e-07 31.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ27058.1 - 1.5e-05 24.7 0.0 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ27058.1 - 0.066 14.0 0.0 0.2 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBZ27058.1 - 0.069 13.1 0.2 0.2 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 CBZ27059.1 - 1.5e-13 51.1 0.0 1.4e-07 31.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ27059.1 - 1.3e-05 24.9 0.0 3.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ27059.1 - 0.063 14.1 0.0 0.18 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBZ27059.1 - 0.063 13.2 0.2 0.21 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 CBZ27060.1 - 5.1e-63 212.6 0.0 6e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27060.1 - 7e-43 146.5 0.0 8.6e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ27060.1 - 5.7e-08 32.0 0.0 7.6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBZ27060.1 - 0.0051 15.9 0.0 0.024 13.7 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4626 PF15422.1 CBZ27060.1 - 0.062 13.2 0.1 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4626) Kinesin PF00225.18 CBZ27061.1 - 6.2e-88 294.7 0.3 2.5e-87 292.7 0.2 2.1 1 0 0 1 1 1 1 Kinesin motor domain HALZ PF02183.13 CBZ27061.1 - 0.029 14.0 0.3 0.029 14.0 0.2 8.0 7 1 1 8 8 8 0 Homeobox associated leucine zipper NPR2 PF06218.6 CBZ27062.1 - 0.0045 15.7 0.0 0.05 12.2 0.0 2.1 2 0 0 2 2 2 1 Nitrogen permease regulator 2 WD40 PF00400.27 CBZ27063.1 - 8.7e-05 22.2 0.0 0.025 14.4 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat UAA PF08449.6 CBZ27066.1 - 7.4e-43 146.6 13.8 1.3e-39 135.8 7.8 3.1 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.15 CBZ27066.1 - 0.87 9.6 14.8 0.23 11.5 2.5 3.4 3 0 0 3 3 3 0 EamA-like transporter family Kelch_4 PF13418.1 CBZ27068.1 - 4.4e-21 74.3 18.6 0.00018 21.1 0.2 7.0 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ27068.1 - 7.3e-21 73.6 7.3 5.2e-05 23.1 0.1 7.3 6 1 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 CBZ27068.1 - 1.8e-18 66.1 25.7 2.2e-05 24.4 0.1 8.6 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_6 PF13964.1 CBZ27068.1 - 1.5e-16 59.7 10.1 0.00033 20.6 0.1 6.3 5 1 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CBZ27068.1 - 3.2e-15 55.3 7.4 0.00028 20.3 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CBZ27068.1 - 7.9e-09 34.9 13.0 0.00014 21.4 0.2 6.0 6 1 0 6 6 6 2 Kelch motif BTB PF00651.26 CBZ27068.1 - 0.00035 20.5 0.1 0.003 17.5 0.0 2.5 3 0 0 3 3 3 1 BTB/POZ domain CheY-binding PF09078.6 CBZ27068.1 - 0.021 14.8 0.5 1.7 8.7 0.0 2.8 3 0 0 3 3 3 0 CheY binding CTD_bind PF04818.8 CBZ27069.1 - 0.45 10.8 2.6 1.6 8.9 1.8 2.0 1 0 0 1 1 1 0 RNA polymerase II-binding domain. MFS_1 PF07690.11 CBZ27070.1 - 3.4e-24 85.2 22.8 3.4e-24 85.2 15.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ27070.1 - 2.9e-17 62.3 1.9 2.9e-17 62.3 1.3 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 CBZ27070.1 - 2.3e-13 49.1 10.5 1e-07 30.3 0.2 3.8 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family AphA_like PF14557.1 CBZ27070.1 - 0.24 10.9 0.4 0.49 9.9 0.0 1.6 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator LSM PF01423.17 CBZ27071.1 - 2.8e-13 49.2 0.1 3.7e-13 48.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain Med20 PF08612.6 CBZ27071.1 - 0.066 12.3 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF2782 PF11191.3 CBZ27071.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) CRAL_TRIO PF00650.15 CBZ27074.1 - 9.4e-13 47.9 0.0 3.1e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain zf-C3HC4_3 PF13920.1 CBZ27075.1 - 2e-09 36.9 10.8 2e-09 36.9 7.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ27075.1 - 3.6 7.3 17.0 0.1 12.3 7.0 1.9 2 0 0 2 2 2 0 zinc-RING finger domain DHC_N2 PF08393.8 CBZ27076.1 - 1.2e-87 294.1 0.1 1.1e-86 290.9 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 CBZ27076.1 - 4.4e-84 282.8 0.0 1.9e-83 280.7 0.0 2.1 1 1 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CBZ27076.1 - 7.6e-82 274.2 0.0 3.5e-81 272.1 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CBZ27076.1 - 1.3e-37 128.8 0.0 2.8e-37 127.7 0.0 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CBZ27076.1 - 1.1e-36 126.1 0.0 9.1e-26 90.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 MT PF12777.2 CBZ27076.1 - 1.2e-35 122.8 2.1 1.9e-35 122.2 1.4 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ27076.1 - 3.7e-29 101.2 0.0 2.9e-10 40.0 0.0 6.4 5 2 0 5 5 4 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ27076.1 - 2.3e-20 73.1 0.1 8.1e-06 26.0 0.0 5.2 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.2 CBZ27076.1 - 1.3e-18 67.0 0.0 7.3e-18 64.6 0.0 2.3 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 CBZ27076.1 - 9.1e-15 54.9 4.2 1.5e-05 25.1 0.0 6.8 7 0 0 7 7 5 3 AAA domain AAA_16 PF13191.1 CBZ27076.1 - 1.1e-13 51.5 14.9 0.025 14.5 0.0 8.3 7 0 0 7 7 5 4 AAA ATPase domain AAA_17 PF13207.1 CBZ27076.1 - 5.3e-10 40.1 0.0 0.37 11.6 0.0 5.5 4 0 0 4 4 4 3 AAA domain FtsK_SpoIIIE PF01580.13 CBZ27076.1 - 5e-08 32.6 0.6 0.0077 15.7 0.0 4.4 4 0 0 4 4 3 2 FtsK/SpoIIIE family AAA_18 PF13238.1 CBZ27076.1 - 2.5e-07 31.0 0.0 0.52 10.6 0.0 5.0 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 CBZ27076.1 - 2.3e-06 27.5 5.9 0.18 11.6 0.0 5.2 5 0 0 5 5 5 2 AAA domain AAA_14 PF13173.1 CBZ27076.1 - 1.2e-05 25.1 0.0 3.2 7.6 0.0 4.7 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 CBZ27076.1 - 0.00025 21.1 0.3 3.8 7.7 0.0 4.5 4 0 0 4 4 4 1 RNA helicase Mg_chelatase PF01078.16 CBZ27076.1 - 0.00042 19.5 5.0 0.17 10.9 0.0 3.8 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 CBZ27076.1 - 0.00045 19.4 0.3 8.8 5.4 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ27076.1 - 0.00046 19.6 0.1 1.6 8.3 0.0 3.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain Sigma54_activat PF00158.21 CBZ27076.1 - 0.00062 19.2 0.0 0.45 9.9 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_10 PF12846.2 CBZ27076.1 - 0.0016 17.9 1.4 13 5.1 0.0 4.2 3 0 0 3 3 3 0 AAA-like domain ABC_tran PF00005.22 CBZ27076.1 - 0.0035 17.6 3.2 2 8.7 0.0 4.4 4 0 0 4 4 3 1 ABC transporter DHC_N1 PF08385.7 CBZ27076.1 - 0.0039 15.6 0.1 0.0039 15.6 0.1 5.1 8 0 0 8 8 8 1 Dynein heavy chain, N-terminal region 1 MobB PF03205.9 CBZ27076.1 - 0.02 14.5 1.9 1.5 8.5 0.0 4.0 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 CBZ27076.1 - 0.077 12.7 0.3 71 3.0 0.0 3.7 3 0 0 3 3 3 0 NTPase DUF87 PF01935.12 CBZ27076.1 - 0.13 12.0 2.3 16 5.2 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function DUF87 Arch_ATPase PF01637.13 CBZ27076.1 - 0.17 11.5 0.0 7.1 6.2 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase ResIII PF04851.10 CBZ27076.1 - 0.19 11.5 0.1 28 4.4 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit TIP49 PF06068.8 CBZ27076.1 - 0.2 10.3 0.5 30 3.1 0.0 3.1 3 0 0 3 3 3 0 TIP49 C-terminus AAA_11 PF13086.1 CBZ27076.1 - 0.6 9.6 9.4 2.6 7.5 0.0 4.2 5 0 0 5 5 4 0 AAA domain MAD PF05557.8 CBZ27076.1 - 0.66 7.9 20.6 0.005 15.0 2.8 3.0 3 0 0 3 3 3 0 Mitotic checkpoint protein Rad17 PF03215.10 CBZ27076.1 - 1.5 7.3 0.3 15 4.1 0.0 2.6 4 0 0 4 4 4 0 Rad17 cell cycle checkpoint protein Myosin_tail_1 PF01576.14 CBZ27076.1 - 2.2 5.8 20.3 0.2 9.3 3.4 2.3 2 0 0 2 2 2 0 Myosin tail DUF4441 PF14536.1 CBZ27076.1 - 3 7.8 0.3 8.2 6.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) AAA_24 PF13479.1 CBZ27076.1 - 4.3 6.8 8.3 9.2 5.7 0.0 4.3 5 0 0 5 5 4 0 AAA domain ADIP PF11559.3 CBZ27076.1 - 5.3 6.9 22.5 0.0062 16.4 1.4 3.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Lactamase_B_2 PF12706.2 CBZ27077.1 - 3e-12 46.4 0.1 4.5e-12 45.9 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBZ27077.1 - 1.6e-07 31.2 0.1 2.9e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBZ27078.1 - 1e-08 35.0 0.0 6.1e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CBZ27078.1 - 2.5e-05 24.0 0.0 5.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Adap_comp_sub PF00928.16 CBZ27079.1 - 1e-82 277.1 0.4 1.4e-82 276.7 0.3 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBZ27079.1 - 0.00082 19.1 0.5 0.0015 18.2 0.4 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.20 CBZ27080.1 - 1.4e-13 50.6 0.0 1.3e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27080.1 - 0.003 16.6 0.0 0.083 11.9 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 CBZ27082.1 - 1e-26 93.6 0.0 3.9e-21 75.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27082.1 - 4.2e-08 32.5 0.0 7.1e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ27082.1 - 6.8e-06 25.2 0.0 1.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like CTP_transf_1 PF01148.15 CBZ27083.1 - 0.56 9.8 9.7 0.86 9.1 6.7 1.3 1 0 0 1 1 1 0 Cytidylyltransferase family ChaC PF04752.7 CBZ27084.1 - 9.7e-49 165.7 0.0 1.2e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein ChaC PF04752.7 CBZ27085.1 - 2.3e-44 151.4 0.1 3.5e-43 147.6 0.0 2.0 1 1 0 1 1 1 1 ChaC-like protein WD40 PF00400.27 CBZ27086.1 - 1.3e-12 47.0 2.2 1.5e-06 27.8 0.0 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat SHS2_Rpb7-N PF03876.12 CBZ27088.1 - 0.00048 20.1 0.0 0.013 15.5 0.0 2.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GTP_EFTU PF00009.22 CBZ27089.1 - 2.7e-36 124.7 2.3 2e-35 121.9 1.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ27089.1 - 6.1e-07 29.4 0.1 1.1e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ27089.1 - 1.9e-05 23.9 0.1 3.5e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CBZ27089.1 - 4.4e-05 23.9 0.0 0.0001 22.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CBZ27089.1 - 0.00011 21.7 0.1 0.00031 20.2 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CBZ27089.1 - 0.00026 20.2 0.0 0.00051 19.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit IF-2 PF11987.3 CBZ27089.1 - 0.0064 16.3 0.0 0.023 14.5 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 Dynamin_N PF00350.18 CBZ27089.1 - 0.0083 15.9 3.3 0.37 10.6 0.1 2.8 2 1 1 3 3 3 2 Dynamin family Arf PF00025.16 CBZ27089.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family WD40 PF00400.27 CBZ27090.1 - 1.3e-26 91.4 17.2 8.6e-05 22.2 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CBZ27090.1 - 0.032 13.7 0.0 0.069 12.6 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 CBZ27090.1 - 0.034 12.8 0.0 6.4 5.4 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like MORN PF02493.15 CBZ27092.1 - 6.4e-06 25.5 12.0 0.16 11.7 0.0 3.7 3 0 0 3 3 3 3 MORN repeat Ribonuc_red_sm PF00268.16 CBZ27094.1 - 3.3e-111 370.7 0.2 4.1e-111 370.5 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Atg8 PF02991.11 CBZ27095.1 - 1.7e-12 47.2 0.0 2e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CBZ27095.1 - 0.00043 20.4 0.0 0.00079 19.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Lebercilin PF15619.1 CBZ27097.1 - 4.8e-27 94.6 577.5 0.012 15.0 10.4 44.4 11 4 44 56 56 56 45 Ciliary protein causing Leber congenital amaurosis disease DUF641 PF04859.7 CBZ27097.1 - 1.9e-15 56.7 434.6 0.34 10.6 7.0 38.1 6 2 52 59 59 59 47 Plant protein of unknown function (DUF641) Myosin_tail_1 PF01576.14 CBZ27097.1 - 1.1e-08 33.3 488.2 2.2e-06 25.7 102.3 11.8 7 2 4 11 11 11 7 Myosin tail Reo_sigmaC PF04582.7 CBZ27097.1 - 6e-06 25.6 139.8 0.1 11.7 2.3 17.6 3 2 9 18 18 18 16 Reovirus sigma C capsid protein CALCOCO1 PF07888.6 CBZ27097.1 - 0.00099 17.5 2.5 0.00099 17.5 1.7 24.4 5 2 17 23 23 23 5 Calcium binding and coiled-coil domain (CALCOCO1) like Tap-RNA_bind PF09162.5 CBZ27097.1 - 1.1 8.9 0.1 2.3 7.8 0.1 1.4 1 0 0 1 1 1 0 Tap, RNA-binding COMP PF11598.3 CBZ27098.1 - 8.6e-57 188.9 372.5 3.1 7.9 0.2 66.4 66 0 0 66 66 66 65 Cartilage oligomeric matrix protein TMF_DNA_bd PF12329.3 CBZ27098.1 - 0.00051 19.7 437.0 0.27 11.0 1.9 63.0 51 14 15 66 66 66 37 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 CBZ27098.1 - 0.0013 18.5 430.4 0.35 10.6 1.2 28.3 4 2 24 34 34 34 27 Autophagy protein 16 (ATG16) Methyltransf_28 PF02636.12 CBZ27099.1 - 4.4e-34 118.0 0.1 6.2e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 CBZ27099.1 - 0.00034 19.7 0.0 0.00063 18.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 CBZ27099.1 - 0.00036 21.0 0.0 0.00099 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ27099.1 - 0.0006 19.4 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ27099.1 - 0.0031 17.9 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ27099.1 - 0.0059 16.6 0.1 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 CBZ27099.1 - 0.057 13.1 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.11 CBZ27099.1 - 0.077 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase zf-DHHC PF01529.15 CBZ27100.1 - 2e-28 98.9 5.4 2.5e-28 98.6 3.3 1.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase polyprenyl_synt PF00348.12 CBZ27101.1 - 4.7e-52 176.3 0.1 6e-52 176.0 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Spc7 PF08317.6 CBZ27102.1 - 0.15 10.6 56.8 0.13 10.9 12.2 3.4 1 1 1 3 3 3 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CBZ27102.1 - 0.4 9.7 20.7 1.5 7.9 2.1 4.1 1 1 4 5 5 5 0 Reovirus sigma C capsid protein DUF948 PF06103.6 CBZ27102.1 - 4.8 7.1 28.0 0.88 9.4 2.4 5.1 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Ribosomal_L28e PF01778.12 CBZ27103.1 - 4.6e-28 97.9 0.6 7.1e-28 97.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 CBZ27103.1 - 3.7e-12 46.2 24.5 3.7e-12 46.2 17.0 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region RNase_H2-Ydr279 PF09468.5 CBZ27103.1 - 0.4 9.8 7.6 0.55 9.3 5.3 1.3 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Exonuc_VII_L PF02601.10 CBZ27103.1 - 2.2 7.3 7.5 2.9 6.9 5.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit MORN PF02493.15 CBZ27105.1 - 4.8e-48 158.1 80.6 1.9e-05 24.0 0.2 12.9 13 0 0 13 13 13 12 MORN repeat EF-hand_1 PF00036.27 CBZ27106.1 - 1.3e-26 89.8 8.5 2.6e-08 32.5 0.3 4.5 4 1 1 5 5 5 4 EF hand EF-hand_7 PF13499.1 CBZ27106.1 - 2.8e-25 88.2 1.9 9.6e-13 48.0 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ27106.1 - 7.6e-21 72.0 5.8 8.4e-08 31.4 0.1 4.3 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CBZ27106.1 - 5.4e-20 70.7 8.9 1.8e-11 43.4 0.3 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBZ27106.1 - 1.4e-18 65.2 10.9 6e-06 25.3 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CBZ27106.1 - 3.3e-07 29.9 2.8 0.038 13.7 0.5 3.3 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CBZ27106.1 - 9.9e-07 28.5 0.0 9.2e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 CBZ27106.1 - 0.021 14.7 0.3 6.6 6.7 0.0 2.7 2 1 0 2 2 2 0 Ca2+ insensitive EF hand FliG_N PF14842.1 CBZ27106.1 - 0.049 13.7 0.5 2.7 8.1 0.1 2.3 2 0 0 2 2 2 0 FliG N-terminal domain SPARC_Ca_bdg PF10591.4 CBZ27106.1 - 0.073 13.0 0.0 0.19 11.7 0.0 1.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_L11 PF00298.14 CBZ27106.1 - 0.085 13.0 0.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain DUF3911 PF13050.1 CBZ27106.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3911) MIP PF00230.15 CBZ27107.1 - 4.3e-24 85.2 13.8 3.2e-23 82.3 9.5 1.9 1 1 0 1 1 1 1 Major intrinsic protein FKBP_C PF00254.23 CBZ27108.1 - 4.3e-29 100.3 0.0 4.9e-29 100.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-tcix PF14952.1 CBZ27109.1 - 0.082 12.2 1.4 0.17 11.2 1.0 1.5 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Pro_isomerase PF00160.16 CBZ27110.1 - 6.1e-37 127.2 0.0 7.7e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EF-hand_8 PF13833.1 CBZ27111.1 - 1.7e-08 33.9 0.2 5.2e-08 32.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EFhand_Ca_insen PF08726.5 CBZ27111.1 - 0.00026 20.8 0.2 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_6 PF13405.1 CBZ27111.1 - 0.026 14.3 0.1 0.2 11.6 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 CBZ27111.1 - 0.027 13.7 0.8 0.1 11.9 0.1 2.2 2 0 0 2 2 2 0 EF hand RNase_H2-Ydr279 PF09468.5 CBZ27111.1 - 3.3 6.8 11.4 14 4.7 0.0 2.1 1 1 1 2 2 2 0 Ydr279p protein family (RNase H2 complex component) TPR_11 PF13414.1 CBZ27112.1 - 0.025 14.2 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 TPR repeat MAM33 PF02330.11 CBZ27113.1 - 7e-15 55.3 0.5 1.9e-14 53.9 0.4 1.8 1 1 0 1 1 1 1 Mitochondrial glycoprotein Metallophos PF00149.23 CBZ27114.1 - 7.9e-07 28.6 0.0 0.00073 18.9 0.0 2.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBZ27114.1 - 0.018 14.8 0.1 0.27 11.0 0.1 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF4440 PF14534.1 CBZ27114.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) HA2 PF04408.18 CBZ27115.1 - 4.2e-17 62.0 0.1 9.7e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBZ27115.1 - 1.2e-12 47.4 0.0 2.9e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ27115.1 - 2.4e-09 36.8 0.0 4.3e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ27115.1 - 1e-05 25.6 0.0 2.9e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain R3H PF01424.17 CBZ27115.1 - 0.00056 19.5 0.1 0.0027 17.3 0.0 2.4 2 0 0 2 2 2 1 R3H domain T2SE PF00437.15 CBZ27115.1 - 0.022 13.6 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 CBZ27115.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Ribosomal_L14e PF01929.12 CBZ27117.1 - 1.8e-23 82.6 2.4 1.8e-23 82.6 1.7 2.2 2 1 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 CBZ27117.1 - 2.2e-05 23.9 0.6 4.5e-05 22.9 0.4 1.5 1 0 0 1 1 1 1 KOW motif CoaE PF01121.15 CBZ27118.1 - 9.6e-42 142.4 0.0 1.8e-41 141.4 0.0 1.4 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 CBZ27118.1 - 0.00018 21.8 0.1 0.065 13.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CBZ27118.1 - 0.00048 20.9 0.1 0.00085 20.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 CBZ27118.1 - 0.0088 15.6 0.1 0.025 14.1 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Cytidylate_kin2 PF13189.1 CBZ27118.1 - 0.016 15.1 0.0 7.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family UCR_Fe-S_N PF10399.4 CBZ27118.1 - 0.052 12.7 3.4 0.18 10.9 2.4 2.0 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal tRNA-synt_2c PF01411.14 CBZ27119.1 - 2.1e-192 640.3 0.0 2.6e-192 639.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CBZ27119.1 - 5.9e-11 42.0 0.0 1.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CBZ27119.1 - 0.0014 18.3 0.8 0.0041 16.7 0.6 1.8 1 0 0 1 1 1 1 DHHA1 domain SpoA PF01052.15 CBZ27120.1 - 0.025 14.1 0.0 0.057 13.0 0.0 1.6 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) PTEN_C2 PF10409.4 CBZ27120.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Ribosomal_L14e PF01929.12 CBZ27121.1 - 1.8e-23 82.6 2.4 1.8e-23 82.6 1.7 2.2 2 1 0 2 2 2 1 Ribosomal protein L14 KOW PF00467.24 CBZ27121.1 - 2.2e-05 23.9 0.6 4.5e-05 22.9 0.4 1.5 1 0 0 1 1 1 1 KOW motif PBP_sp32 PF07222.7 CBZ27122.1 - 0.18 10.9 4.1 0.16 11.1 1.6 1.7 2 0 0 2 2 2 0 Proacrosin binding protein sp32 RNase_PH PF01138.16 CBZ27123.1 - 5.1e-09 36.5 0.0 9.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBZ27123.1 - 0.00075 19.3 0.1 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Pribosyltran_N PF13793.1 CBZ27123.1 - 0.08 12.6 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 N-terminal domain of ribose phosphate pyrophosphokinase Metallophos PF00149.23 CBZ27125.1 - 1.6e-08 34.1 0.8 6.9e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBZ27125.1 - 4.6e-07 29.8 0.0 8.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Motile_Sperm PF00635.21 CBZ27127.1 - 3e-08 33.2 0.0 32 4.2 0.0 9.1 11 0 0 11 11 11 0 MSP (Major sperm protein) domain PapD-like PF14874.1 CBZ27127.1 - 0.00033 20.5 15.5 0.014 15.2 0.0 7.2 7 1 1 8 8 8 2 Flagellar-associated PapD-like Gryzun-like PF12742.2 CBZ27127.1 - 0.022 14.5 0.0 2.3 8.1 0.0 3.3 3 0 0 3 3 3 0 Gryzun, putative Golgi trafficking DUF1034 PF06280.7 CBZ27127.1 - 0.08 13.3 7.2 1.7 9.0 0.0 6.3 8 0 0 8 8 8 0 Fn3-like domain (DUF1034) MYCBPAP PF14646.1 CBZ27127.1 - 0.14 10.8 0.0 12 4.4 0.0 3.7 4 0 0 4 4 4 0 MYCBP-associated protein family CAF1 PF04857.15 CBZ27128.1 - 7.7e-62 208.9 0.3 1.1e-61 208.4 0.2 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease cobW PF02492.14 CBZ27130.1 - 4.4e-25 88.1 0.2 6.3e-25 87.6 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CBZ27130.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CBZ27130.1 - 0.0062 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ27130.1 - 0.0073 16.1 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ27130.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain CobW_C PF07683.9 CBZ27130.1 - 0.015 14.9 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.1 CBZ27130.1 - 0.036 14.0 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 CBZ27130.1 - 0.038 13.4 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain LAMTOR PF15454.1 CBZ27130.1 - 0.072 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator TrwB_AAD_bind PF10412.4 CBZ27130.1 - 0.13 10.8 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 CBZ27130.1 - 0.14 11.6 0.0 0.42 10.1 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF445 PF04286.7 CBZ27135.1 - 0.012 15.1 1.0 0.013 15.0 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF445) UTP15_C PF09384.5 CBZ27137.1 - 2.4e-37 127.9 1.0 3.9e-37 127.2 0.7 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CBZ27137.1 - 2.1e-20 71.7 0.6 9.1e-05 22.1 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat AhpC-TSA PF00578.16 CBZ27138.1 - 4.8e-40 136.1 0.0 6.2e-40 135.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CBZ27138.1 - 9.6e-17 60.8 0.0 1.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 CBZ27138.1 - 6.2e-09 35.3 0.1 1.6e-08 34.0 0.1 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin EIAV_GP90 PF00971.13 CBZ27138.1 - 0.1 11.0 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 EIAV coat protein, gp90 Pro_isomerase PF00160.16 CBZ27139.1 - 6.4e-46 156.3 0.0 1e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YscJ_FliF PF01514.12 CBZ27139.1 - 0.039 13.1 0.3 3.1 6.8 0.1 2.2 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family DUF4544 PF15077.1 CBZ27139.1 - 0.21 11.0 3.9 0.32 10.4 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) vATP-synt_E PF01991.13 CBZ27139.1 - 1.2 8.3 6.3 1.7 7.8 4.4 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Arginase PF00491.16 CBZ27141.1 - 1.4e-36 126.2 0.0 1.6e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family IspD PF01128.14 CBZ27141.1 - 0.045 13.2 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Tropomyosin_1 PF12718.2 CBZ27142.1 - 0.00033 20.5 1.8 0.00033 20.5 1.2 4.4 2 1 3 5 5 5 2 Tropomyosin like FliJ PF02050.11 CBZ27142.1 - 0.0086 16.1 5.5 0.0086 16.1 3.8 4.9 3 2 1 4 4 4 1 Flagellar FliJ protein KaiC PF06745.8 CBZ27142.1 - 0.15 11.1 4.4 0.43 9.6 3.0 1.9 1 1 0 1 1 1 0 KaiC ZYG-11_interact PF05884.7 CBZ27142.1 - 0.45 9.5 3.9 1.2 8.1 1.8 2.0 1 1 1 2 2 2 0 Interactor of ZYG-11 DUF1767 PF08585.7 CBZ27143.1 - 3.6e-13 49.6 0.0 6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Methyltransf_16 PF10294.4 CBZ27144.1 - 3e-17 62.6 0.0 4.1e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 CBZ27144.1 - 1.4e-09 37.7 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ27144.1 - 2.1e-08 34.5 0.0 5.8e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBZ27144.1 - 4.6e-07 29.3 0.1 6.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CBZ27144.1 - 1.3e-05 25.2 0.1 2e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ27144.1 - 1.6e-05 25.4 0.1 2.6e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ27144.1 - 0.00024 21.5 0.1 0.0008 19.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ27144.1 - 0.00062 20.0 0.1 0.0012 19.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 CBZ27144.1 - 0.0009 18.0 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_23 PF13489.1 CBZ27144.1 - 0.0056 16.4 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CBZ27144.1 - 0.0064 15.6 0.0 0.0081 15.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 CBZ27144.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) MethyltransfD12 PF02086.10 CBZ27144.1 - 0.05 13.0 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_9 PF08003.6 CBZ27144.1 - 0.054 12.1 0.0 0.082 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) NTP_transferase PF00483.18 CBZ27145.1 - 1.4e-44 152.3 0.0 2.1e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CBZ27145.1 - 3.4e-12 46.7 0.0 4.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 CBZ27145.1 - 1.4e-11 43.2 11.5 1e-06 27.9 2.0 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBZ27145.1 - 0.017 14.6 1.1 0.017 14.6 0.8 3.9 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 CBZ27145.1 - 0.033 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Beach PF02138.13 CBZ27146.1 - 6.8e-90 301.1 0.0 1.6e-89 299.9 0.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.1 CBZ27146.1 - 6.4e-07 29.7 0.1 2.3e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 CBZ27146.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Pro_isomerase PF00160.16 CBZ27147.1 - 4e-13 49.8 0.0 4.9e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_C PF00137.16 CBZ27148.1 - 1.2e-26 92.3 31.3 1.2e-15 57.1 6.9 2.2 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.8 CBZ27148.1 - 1.9 6.4 6.3 5.2 5.0 0.3 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Abhydrolase_6 PF12697.2 CBZ27149.1 - 4e-26 92.2 0.9 6.5e-26 91.6 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ27149.1 - 1.5e-12 47.4 0.1 2.5e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ27149.1 - 2.1e-10 40.5 0.1 4e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 CBZ27149.1 - 4.7e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.3 CBZ27149.1 - 0.00022 21.0 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 CBZ27149.1 - 0.0038 16.6 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) LRR_6 PF13516.1 CBZ27150.1 - 2.2e-10 39.4 14.5 0.23 11.6 0.0 9.3 10 1 0 10 10 10 5 Leucine Rich repeat LRR_8 PF13855.1 CBZ27150.1 - 1.6e-06 27.7 2.1 0.058 13.1 0.0 5.2 3 2 2 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 CBZ27150.1 - 8.1e-06 25.3 3.9 0.74 9.5 0.0 5.5 3 2 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBZ27150.1 - 0.039 14.1 10.9 71 4.3 0.0 8.0 9 1 0 9 9 9 0 Leucine rich repeat cNMP_binding PF00027.24 CBZ27151.1 - 5.2e-09 35.8 0.3 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF342 PF03961.8 CBZ27152.1 - 0.025 12.9 0.5 0.032 12.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3810 PF12725.2 CBZ27152.1 - 0.12 11.2 0.3 0.15 10.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DivIC PF04977.10 CBZ27152.1 - 0.13 11.7 7.9 0.057 12.9 1.3 2.3 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 CBZ27152.1 - 0.21 10.6 4.1 0.27 10.2 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 CBZ27152.1 - 0.23 11.2 7.9 0.1 12.4 1.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3584 PF12128.3 CBZ27152.1 - 0.98 6.6 11.3 1.3 6.2 7.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2205 PF10224.4 CBZ27152.1 - 3.1 7.4 9.3 5 6.7 1.6 2.5 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DOR PF14839.1 CBZ27152.1 - 5.3 6.7 8.1 7.1 6.3 5.6 1.3 1 0 0 1 1 1 0 DOR family YjgF_endoribonc PF14588.1 CBZ27155.1 - 1.5e-31 109.3 0.1 1.6e-31 109.2 0.1 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.16 CBZ27155.1 - 2.4e-19 69.2 0.1 3.8e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Herpes_U34 PF04541.8 CBZ27155.1 - 0.14 11.0 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus virion protein U34 ABC_membrane PF00664.18 CBZ27156.1 - 8.1e-52 176.3 30.3 1.7e-27 96.5 6.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ27156.1 - 6.8e-50 168.9 0.0 6e-26 91.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 CBZ27156.1 - 3.7e-09 35.9 0.1 0.0018 17.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CBZ27156.1 - 5.4e-09 35.6 0.4 0.15 11.2 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CBZ27156.1 - 8e-09 35.1 0.1 2.8e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 CBZ27156.1 - 2.8e-08 34.0 0.0 0.17 11.7 0.0 4.2 4 0 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.13 CBZ27156.1 - 8.9e-07 28.5 0.3 0.022 14.2 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 CBZ27156.1 - 3.1e-06 26.2 0.0 0.0041 16.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 CBZ27156.1 - 7.6e-06 26.0 0.1 0.002 18.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ27156.1 - 9.5e-06 25.7 0.1 0.02 15.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CBZ27156.1 - 1.2e-05 24.9 0.0 0.0027 17.2 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 CBZ27156.1 - 1.3e-05 25.6 0.0 0.023 15.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CBZ27156.1 - 1.5e-05 24.5 0.1 0.04 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 CBZ27156.1 - 1.9e-05 25.1 0.3 0.29 11.6 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 CBZ27156.1 - 6.2e-05 22.9 1.8 0.16 11.7 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 DUF258 PF03193.11 CBZ27156.1 - 0.00011 21.4 0.2 0.012 14.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CBZ27156.1 - 0.00018 21.4 0.4 0.66 9.9 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 CBZ27156.1 - 0.00018 21.1 0.9 0.078 12.6 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.1 CBZ27156.1 - 0.00049 20.8 0.2 2.3 9.0 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CBZ27156.1 - 0.00062 19.6 0.0 0.098 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 CBZ27156.1 - 0.00088 18.0 0.2 0.33 9.5 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 CBZ27156.1 - 0.0011 18.6 1.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CBZ27156.1 - 0.0014 18.9 0.0 2 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBZ27156.1 - 0.0039 17.0 0.1 0.61 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CBZ27156.1 - 0.0044 16.4 2.6 0.29 10.5 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CBZ27156.1 - 0.0054 16.4 0.0 0.42 10.2 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase CAP_GLY PF01302.20 CBZ27156.1 - 0.0072 16.0 0.0 0.056 13.1 0.0 2.3 2 0 0 2 2 2 1 CAP-Gly domain ArgK PF03308.11 CBZ27156.1 - 0.01 14.6 0.2 3.1 6.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 CBZ27156.1 - 0.013 15.6 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 CBZ27156.1 - 0.014 15.3 0.0 0.26 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CBZ27156.1 - 0.019 14.5 0.2 3.3 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 CBZ27156.1 - 0.02 14.2 1.0 4.1 6.6 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 CBZ27156.1 - 0.03 13.8 1.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 CBZ27156.1 - 0.03 13.4 0.1 7.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 CBZ27156.1 - 0.054 12.3 0.1 5.7 5.6 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain Adeno_IVa2 PF02456.10 CBZ27156.1 - 0.13 10.8 0.0 0.6 8.6 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein Dynamin_N PF00350.18 CBZ27156.1 - 0.19 11.5 2.7 2.2 8.0 0.4 2.6 3 0 0 3 3 2 0 Dynamin family ATP-synt_ab PF00006.20 CBZ27156.1 - 0.21 11.0 1.3 1.7 8.1 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.13 CBZ27156.1 - 0.46 9.4 0.2 5.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 CBZ27156.1 - 0.75 9.4 2.2 9.8 5.8 0.2 2.7 3 0 0 3 3 2 0 NTPase DAP3 PF10236.4 CBZ27156.1 - 1 8.2 2.2 6.7 5.5 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_membrane PF00664.18 CBZ27157.1 - 2.9e-54 184.3 30.6 9.9e-34 116.9 8.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ27157.1 - 6.4e-50 169.0 0.0 6e-26 91.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 CBZ27157.1 - 3.7e-09 35.9 0.1 0.0018 17.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 CBZ27157.1 - 6.3e-09 35.5 0.1 2.7e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBZ27157.1 - 1.5e-08 34.1 0.4 0.17 11.1 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBZ27157.1 - 7.6e-08 32.6 0.0 0.17 11.7 0.0 4.1 4 0 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.13 CBZ27157.1 - 8.5e-07 28.6 0.3 0.022 14.2 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 CBZ27157.1 - 1.5e-06 27.8 0.1 0.0027 17.2 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 CBZ27157.1 - 2.5e-06 26.6 0.0 0.0041 16.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 CBZ27157.1 - 3.5e-06 27.1 0.2 0.02 15.0 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CBZ27157.1 - 7.1e-06 26.1 0.0 0.0022 17.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 CBZ27157.1 - 1.3e-05 25.6 0.0 0.023 15.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CBZ27157.1 - 1.3e-05 24.7 0.1 0.04 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain Miro PF08477.8 CBZ27157.1 - 2e-05 25.0 0.3 0.29 11.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 CBZ27157.1 - 5.7e-05 23.0 1.8 0.16 11.7 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 DUF258 PF03193.11 CBZ27157.1 - 9.9e-05 21.5 0.2 0.012 14.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CBZ27157.1 - 0.00017 21.4 0.4 0.66 9.9 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 CBZ27157.1 - 0.00022 20.9 0.9 0.078 12.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 CBZ27157.1 - 0.00063 19.6 0.0 0.098 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBZ27157.1 - 0.00065 20.5 0.2 2.3 9.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.4 CBZ27157.1 - 0.00092 17.9 0.2 0.33 9.5 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 CBZ27157.1 - 0.0011 18.6 1.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CBZ27157.1 - 0.0015 18.8 0.0 2 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBZ27157.1 - 0.0038 17.0 0.1 0.61 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CBZ27157.1 - 0.0039 16.6 2.6 0.29 10.5 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CBZ27157.1 - 0.0061 16.2 0.0 0.42 10.2 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase ArgK PF03308.11 CBZ27157.1 - 0.011 14.5 0.2 3.1 6.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 CBZ27157.1 - 0.012 15.7 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 CBZ27157.1 - 0.014 15.3 0.0 0.26 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain CAP_GLY PF01302.20 CBZ27157.1 - 0.016 14.8 0.0 0.055 13.1 0.0 1.9 2 0 0 2 2 1 0 CAP-Gly domain AAA_30 PF13604.1 CBZ27157.1 - 0.016 14.7 0.7 3.3 7.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.7 CBZ27157.1 - 0.021 14.1 1.0 4.1 6.6 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein Zeta_toxin PF06414.7 CBZ27157.1 - 0.028 13.5 0.1 7.1 5.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 CBZ27157.1 - 0.044 12.6 0.1 5.8 5.6 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.20 CBZ27157.1 - 0.22 11.0 0.9 1.9 7.9 0.0 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 CBZ27157.1 - 0.27 10.7 5.1 2.6 7.4 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 CBZ27157.1 - 0.38 10.5 3.6 2.2 8.0 0.4 2.5 2 0 0 2 2 2 0 Dynamin family Septin PF00735.13 CBZ27157.1 - 0.47 9.4 0.2 5.9 5.8 0.0 2.1 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 CBZ27157.1 - 0.76 9.4 2.2 9.8 5.8 0.2 2.7 3 0 0 3 3 2 0 NTPase DAP3 PF10236.4 CBZ27157.1 - 0.99 8.2 2.2 6.7 5.5 0.1 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 WBP-1 PF11669.3 CBZ27160.1 - 0.0031 17.5 0.8 0.0054 16.7 0.6 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 DUF4381 PF14316.1 CBZ27160.1 - 0.007 16.4 2.1 0.0077 16.3 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) DUF3311 PF11755.3 CBZ27160.1 - 0.0094 15.4 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3311) Phage_B PF02304.10 CBZ27160.1 - 0.89 9.8 4.4 18 5.6 1.6 2.2 2 0 0 2 2 2 0 Scaffold protein B Yip1 PF04893.12 CBZ27161.1 - 1.3e-16 60.6 17.3 1.8e-16 60.1 11.9 1.3 1 1 0 1 1 1 1 Yip1 domain DUF2964 PF11177.3 CBZ27161.1 - 0.053 13.4 1.2 0.11 12.4 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) DUF1282 PF06930.7 CBZ27161.1 - 0.91 9.1 14.1 1.5 8.4 9.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) ABC_membrane PF00664.18 CBZ27162.1 - 5.9e-69 232.5 25.9 8.5e-39 133.6 2.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ27162.1 - 6.2e-50 169.0 0.0 6e-26 91.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 CBZ27162.1 - 3.4e-09 36.1 0.3 0.0014 18.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CBZ27162.1 - 1.2e-08 34.4 0.8 0.16 11.1 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 CBZ27162.1 - 1.5e-08 34.2 0.1 5.6e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain CAP_GLY PF01302.20 CBZ27162.1 - 1.8e-08 33.9 0.0 5.3e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 CAP-Gly domain AAA_21 PF13304.1 CBZ27162.1 - 7.4e-08 32.6 0.0 2 8.2 0.2 4.2 3 1 1 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.13 CBZ27162.1 - 4.6e-06 26.2 0.4 0.11 11.9 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family Miro PF08477.8 CBZ27162.1 - 1.1e-05 25.8 0.3 0.12 12.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 CBZ27162.1 - 2.3e-05 23.4 0.1 0.036 12.9 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 CBZ27162.1 - 4.8e-05 22.9 0.2 0.12 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 CBZ27162.1 - 7.6e-05 22.8 0.1 0.23 11.6 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CBZ27162.1 - 0.00011 22.9 0.2 0.57 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CBZ27162.1 - 0.00014 22.2 0.2 0.24 11.6 0.1 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CBZ27162.1 - 0.00018 20.7 0.4 0.018 14.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CBZ27162.1 - 0.00019 21.3 0.2 0.67 9.9 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 CBZ27162.1 - 0.00057 19.7 2.3 0.5 10.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_16 PF13191.1 CBZ27162.1 - 0.0007 19.6 0.0 0.27 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CBZ27162.1 - 0.0018 18.1 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CBZ27162.1 - 0.002 17.8 1.0 0.68 9.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain TrwB_AAD_bind PF10412.4 CBZ27162.1 - 0.0028 16.3 1.1 0.58 8.7 0.1 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 CBZ27162.1 - 0.003 17.8 0.0 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CBZ27162.1 - 0.0035 17.0 2.4 1.6 8.4 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 CBZ27162.1 - 0.0046 16.5 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 CBZ27162.1 - 0.0059 16.4 0.2 0.91 9.3 0.1 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CBZ27162.1 - 0.013 14.9 0.5 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 CBZ27162.1 - 0.021 14.9 0.0 2.8 8.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Dynamin_N PF00350.18 CBZ27162.1 - 0.023 14.5 0.6 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Septin PF00735.13 CBZ27162.1 - 0.1 11.6 0.3 1.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 CBZ27162.1 - 0.11 11.9 2.3 6.2 6.3 0.2 3.7 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 CBZ27162.1 - 0.15 11.5 2.5 4.3 6.8 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.7 CBZ27162.1 - 0.26 10.5 0.8 9.6 5.4 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ABC_ATPase PF09818.4 CBZ27162.1 - 0.31 9.5 1.2 0.71 8.3 0.2 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DLIC PF05783.6 CBZ27162.1 - 0.34 9.5 0.0 0.56 8.8 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Zeta_toxin PF06414.7 CBZ27162.1 - 1.1 8.2 3.6 7.1 5.6 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin KaiC PF06745.8 CBZ27162.1 - 1.2 8.1 3.0 18 4.3 0.1 2.7 3 0 0 3 3 3 0 KaiC Arginosuc_synth PF00764.14 CBZ27163.1 - 1.6e-148 494.8 0.0 1.9e-148 494.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase adh_short_C2 PF13561.1 CBZ27164.1 - 1.4e-18 67.5 0.0 1.3e-17 64.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CBZ27164.1 - 6.4e-10 39.1 1.6 1.6e-05 24.8 0.5 3.0 2 1 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.16 CBZ27164.1 - 0.027 13.8 0.1 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.5 CBZ27164.1 - 0.039 13.6 0.2 0.087 12.4 0.1 1.6 1 0 0 1 1 1 0 KR domain zf-C3HC4 PF00097.20 CBZ27165.1 - 1.3e-06 27.9 7.4 3.5e-06 26.5 5.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ27165.1 - 0.0018 17.9 7.4 0.0057 16.3 5.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ27165.1 - 0.0057 16.5 8.9 0.013 15.3 6.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TF_Zn_Ribbon PF08271.7 CBZ27165.1 - 0.067 12.5 5.4 0.18 11.1 3.7 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RING_6 PF14835.1 CBZ27165.1 - 0.29 10.9 5.4 2 8.2 3.8 2.3 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBZ27165.1 - 0.4 10.4 7.5 0.041 13.5 1.8 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBZ27165.1 - 0.56 10.2 16.3 0.05 13.6 7.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ27165.1 - 1.4 8.8 10.1 4.8 7.1 7.0 1.9 1 0 0 1 1 1 0 Ring finger domain Hus1 PF04005.7 CBZ27166.1 - 7.4e-82 274.5 0.0 8.3e-82 274.4 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein tRNA-synt_1b PF00579.20 CBZ27167.1 - 1.7e-18 66.8 0.0 3.3e-18 65.8 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF3729 PF12526.3 CBZ27167.1 - 0.47 11.8 3.4 0.92 10.8 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) AAA_16 PF13191.1 CBZ27168.1 - 0.00023 21.2 0.0 0.0008 19.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 CBZ27168.1 - 0.0048 17.2 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 CBZ27168.1 - 0.0085 15.9 1.5 0.014 15.2 0.0 2.2 2 1 0 2 2 1 1 AAA domain tRNA_lig_kinase PF08303.6 CBZ27168.1 - 0.0086 15.9 0.0 0.069 13.0 0.0 2.1 1 1 0 1 1 1 1 tRNA ligase kinase domain AAA_5 PF07728.9 CBZ27168.1 - 0.0089 15.7 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBZ27168.1 - 0.035 13.1 0.0 0.075 12.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CBZ27168.1 - 0.036 14.3 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 CBZ27168.1 - 0.042 13.0 0.0 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 CBZ27168.1 - 0.044 13.4 0.0 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 CBZ27168.1 - 0.052 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CBZ27168.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 CBZ27168.1 - 0.073 13.2 0.0 0.5 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CBZ27168.1 - 0.16 12.7 0.0 0.39 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Proteasom_PSMB PF10508.4 CBZ27168.1 - 0.65 8.2 0.0 0.98 7.6 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit AAA_21 PF13304.1 CBZ27168.1 - 1 9.2 0.0 1.5 8.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sporozoite_P67 PF05642.6 CBZ27168.1 - 5 4.8 9.9 4.2 5.1 0.2 2.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen V-ATPase_G PF03179.10 CBZ27171.1 - 8.1e-22 77.5 13.9 8.9e-22 77.3 9.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF4521 PF15021.1 CBZ27171.1 - 0.032 13.8 0.3 0.034 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Sigma70_r3 PF04539.11 CBZ27171.1 - 0.13 12.1 0.6 0.13 12.1 0.4 1.8 2 0 0 2 2 2 0 Sigma-70 region 3 Prp19_bind PF06991.6 CBZ27171.1 - 0.23 10.7 10.0 0.27 10.4 6.9 1.0 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain YlqD PF11068.3 CBZ27171.1 - 0.23 11.4 7.3 0.27 11.2 5.0 1.2 1 0 0 1 1 1 0 YlqD protein DUF2422 PF10337.4 CBZ27171.1 - 0.53 9.0 3.3 0.58 8.8 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) IncA PF04156.9 CBZ27171.1 - 0.62 9.6 6.5 0.75 9.3 4.5 1.1 1 0 0 1 1 1 0 IncA protein PKK PF12474.3 CBZ27171.1 - 0.73 9.5 11.1 3.1 7.5 7.7 1.9 1 1 0 1 1 1 0 Polo kinase kinase Rabaptin PF03528.10 CBZ27171.1 - 0.83 9.5 7.2 0.94 9.4 4.5 1.5 1 1 0 1 1 1 0 Rabaptin Frankia_peptide PF14407.1 CBZ27171.1 - 2.3 8.0 8.1 43 3.9 5.6 2.6 1 1 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF3154 PF11351.3 CBZ27171.1 - 2.5 7.8 8.5 0.53 10.0 1.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) DUF4407 PF14362.1 CBZ27171.1 - 3.3 6.5 12.0 4.1 6.2 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADH_N PF08240.7 CBZ27174.1 - 7.2e-27 93.3 8.4 7.2e-27 93.3 5.8 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBZ27174.1 - 4.8e-24 84.3 0.0 8.8e-24 83.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CBZ27174.1 - 2.3e-06 26.8 0.1 3.9e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CBZ27174.1 - 0.0001 22.3 0.2 0.00026 21.1 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 CBZ27174.1 - 0.00012 21.9 0.7 0.00023 21.0 0.5 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 CBZ27174.1 - 0.00029 20.4 0.3 0.00052 19.6 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.1 CBZ27174.1 - 0.00052 20.0 0.0 0.00085 19.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 CBZ27174.1 - 0.0044 16.6 0.4 0.0069 16.0 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 CBZ27174.1 - 0.018 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.13 CBZ27174.1 - 0.055 13.4 0.1 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 CBZ27174.1 - 0.09 13.2 0.2 0.17 12.3 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CBZ27174.1 - 0.12 11.8 1.0 0.18 11.2 0.2 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 CBZ27174.1 - 2.7 7.8 4.9 7.6 6.3 2.0 2.5 2 1 1 3 3 3 0 ThiF family ABC_tran PF00005.22 CBZ27176.1 - 4e-30 104.9 0.0 7.6e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 CBZ27176.1 - 1.7e-24 86.1 16.3 1.7e-24 86.1 11.3 2.9 3 0 0 3 3 3 1 ABC-2 type transporter AAA_21 PF13304.1 CBZ27176.1 - 2.2e-06 27.8 0.0 7.6e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ27176.1 - 0.00018 21.5 0.1 0.00041 20.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CBZ27176.1 - 0.00095 18.6 0.1 0.0026 17.2 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 CBZ27176.1 - 0.0011 18.1 15.9 0.0011 18.1 11.0 2.2 2 0 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 CBZ27176.1 - 0.002 17.3 0.1 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBZ27176.1 - 0.012 16.4 0.1 0.026 15.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBZ27176.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CBZ27176.1 - 0.027 14.2 0.2 0.2 11.3 0.2 2.5 2 0 0 2 2 1 0 Part of AAA domain AAA_22 PF13401.1 CBZ27176.1 - 0.027 14.6 0.1 0.085 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 CBZ27176.1 - 0.041 12.6 0.5 0.077 11.7 0.4 1.3 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 CBZ27176.1 - 0.051 13.8 0.4 0.11 12.7 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 CBZ27176.1 - 0.078 12.3 1.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CBZ27176.1 - 0.092 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 CBZ27176.1 - 0.097 12.6 0.3 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CBZ27176.1 - 0.13 12.1 0.0 0.78 9.6 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 CBZ27176.1 - 0.14 11.7 0.1 0.25 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CBZ27176.1 - 0.2 10.3 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF3678 PF12435.3 CBZ27179.1 - 9.1 5.9 12.5 1.3 8.6 5.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Aldose_epim PF01263.15 CBZ27180.1 - 4.7e-55 186.8 0.0 9.3e-54 182.5 0.0 2.0 1 1 0 1 1 1 1 Aldose 1-epimerase FtsX PF02687.16 CBZ27182.1 - 4.4e-25 87.7 35.7 5.9e-14 51.8 7.4 5.3 5 1 1 6 6 6 3 FtsX-like permease family CHAP PF05257.11 CBZ27183.1 - 3.9e-09 36.2 0.1 2.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 CHAP domain DUF3035 PF11233.3 CBZ27183.1 - 0.048 13.7 0.8 0.048 13.7 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) DUF1664 PF07889.7 CBZ27185.1 - 0.0012 18.6 6.3 0.0012 18.6 4.4 10.9 7 4 5 14 14 14 3 Protein of unknown function (DUF1664) AMPKBI PF04739.10 CBZ27186.1 - 1.8e-17 63.0 0.1 3.1e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain ABC_membrane_2 PF06472.10 CBZ27187.1 - 0.22 10.6 3.4 1.1 8.3 0.2 2.1 2 0 0 2 2 2 0 ABC transporter transmembrane region 2 SET PF00856.23 CBZ27189.1 - 6e-14 52.6 0.0 2.1e-13 50.9 0.0 1.8 1 1 0 1 1 1 1 SET domain SecG PF03840.9 CBZ27189.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase SecG subunit FtsJ PF01728.14 CBZ27190.1 - 2e-48 164.7 0.0 2.4e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 CBZ27190.1 - 0.0043 16.7 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AMP-binding PF00501.23 CBZ27191.1 - 7.8e-89 297.9 0.2 9.7e-89 297.6 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ27191.1 - 6.7e-15 55.8 0.3 1.6e-14 54.5 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_6 PF13405.1 CBZ27192.1 - 1.3e-08 34.0 0.1 0.0091 15.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 CBZ27192.1 - 1.1e-05 24.3 0.1 0.0056 15.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 CBZ27192.1 - 0.00011 21.7 0.4 0.11 12.1 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.1 CBZ27192.1 - 0.00013 22.0 0.0 0.0026 17.8 0.0 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CBZ27192.1 - 0.0014 17.8 0.1 0.57 9.6 0.0 2.5 2 0 0 2 2 2 2 EF hand XRN_N PF03159.13 CBZ27193.1 - 8.9e-46 156.1 0.0 2.1e-45 154.9 0.0 1.7 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Laminin_II PF06009.7 CBZ27194.1 - 0.64 9.7 4.4 2.8 7.6 1.8 2.3 1 1 1 2 2 2 0 Laminin Domain II GFO_IDH_MocA PF01408.17 CBZ27195.1 - 9.4e-14 51.9 1.5 1.4e-12 48.1 0.1 2.8 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 CBZ27195.1 - 0.018 15.4 1.3 0.038 14.4 0.1 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 CBZ27195.1 - 0.025 14.2 0.1 0.1 12.3 0.1 2.1 1 0 0 1 1 1 0 Rossmann-like domain Shikimate_DH PF01488.15 CBZ27195.1 - 0.11 12.6 0.3 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 CBZ27196.1 - 3e-16 60.0 0.2 5.2e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CAF1 PF04857.15 CBZ27199.1 - 7.3e-42 143.5 0.0 1e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Kelch_3 PF13415.1 CBZ27200.1 - 8.3e-14 51.2 11.7 2.2e-06 27.6 0.1 7.3 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.1 CBZ27200.1 - 1.2e-13 50.5 8.9 0.0017 18.1 0.0 6.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ27200.1 - 3.7e-10 39.5 14.2 0.0018 18.1 1.0 5.1 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 CBZ27200.1 - 5.5e-09 35.8 5.7 0.4 10.9 0.1 5.8 4 1 1 5 5 5 4 Kelch motif Kelch_1 PF01344.20 CBZ27200.1 - 5.7e-07 28.9 0.1 0.03 13.8 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 CBZ27200.1 - 2.2e-06 27.1 4.0 7.2 6.5 0.2 5.1 4 1 0 4 4 4 4 Kelch motif tRNA_bind PF01588.15 CBZ27201.1 - 6.3e-13 48.3 0.7 8e-13 48.0 0.5 1.1 1 0 0 1 1 1 1 Putative tRNA binding domain zf-RanBP PF00641.13 CBZ27201.1 - 7.2e-06 25.0 1.4 1.2e-05 24.2 1.0 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others GCC2_GCC3 PF07699.8 CBZ27201.1 - 0.002 17.6 0.4 0.0041 16.6 0.3 1.5 1 0 0 1 1 1 1 GCC2 and GCC3 DZR PF12773.2 CBZ27201.1 - 0.0058 16.4 1.0 0.012 15.4 0.7 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 CBZ27201.1 - 0.03 13.5 2.8 0.066 12.4 1.9 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Cache_1 PF02743.13 CBZ27201.1 - 0.14 11.7 0.2 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Cache domain zinc_ribbon_2 PF13240.1 CBZ27201.1 - 0.4 10.2 4.1 0.85 9.1 2.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Lactamase_B PF00753.22 CBZ27202.1 - 6.1e-11 42.3 2.2 3.8e-08 33.2 0.3 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily PAP2 PF01569.16 CBZ27203.1 - 2.9e-12 46.3 0.2 7.9e-12 44.9 0.0 1.8 1 1 1 2 2 2 1 PAP2 superfamily MspA PF09203.6 CBZ27203.1 - 0.083 12.3 0.1 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 MspA ThiF PF00899.16 CBZ27204.1 - 3.6e-48 162.8 0.9 1.7e-33 115.3 0.0 2.7 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 CBZ27204.1 - 5.2e-30 102.8 0.5 1.5e-21 75.7 0.0 2.9 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 CBZ27204.1 - 5.5e-29 100.8 0.0 9.8e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 CBZ27204.1 - 2.9e-24 84.1 0.9 6.7e-21 73.3 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CBZ27204.1 - 0.0059 16.6 1.0 1.9 8.6 0.0 2.8 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DUF3323 PF11796.3 CBZ27204.1 - 0.1 11.9 0.3 0.39 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) Kinesin PF00225.18 CBZ27205.1 - 3.1e-87 292.4 0.0 6.3e-87 291.3 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain CALCOCO1 PF07888.6 CBZ27205.1 - 3 6.0 24.4 1.6 6.9 1.3 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like UPF0184 PF03670.8 CBZ27205.1 - 7.3 6.8 8.1 5.1 7.3 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) FliD_N PF02465.13 CBZ27205.1 - 9.2 6.6 11.4 1.9 8.9 0.9 3.3 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus MYCBPAP PF14646.1 CBZ27206.1 - 4.4e-08 32.2 8.1 0.0005 18.9 0.0 3.5 4 0 0 4 4 4 3 MYCBP-associated protein family HemY_N PF07219.8 CBZ27209.1 - 0.0027 17.2 3.8 0.0036 16.8 0.7 2.2 2 0 0 2 2 2 1 HemY protein N-terminus DUF3784 PF12650.2 CBZ27209.1 - 0.19 11.6 2.2 1.3 9.0 1.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3784) TMEM192 PF14802.1 CBZ27209.1 - 0.67 8.7 2.3 0.99 8.2 1.6 1.2 1 0 0 1 1 1 0 TMEM192 family BING4CT PF08149.6 CBZ27211.1 - 2.8e-32 110.0 0.1 3e-31 106.7 0.0 2.4 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 CBZ27211.1 - 1.1e-09 37.7 0.3 5.4e-07 29.2 0.0 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat Sec10 PF07393.6 CBZ27212.1 - 1.3e-29 102.9 7.1 2.1e-26 92.3 0.1 3.2 3 0 0 3 3 3 3 Exocyst complex component Sec10 Staph_haemo PF05480.6 CBZ27213.1 - 0.00076 19.1 2.4 0.0012 18.5 1.1 1.7 2 0 0 2 2 2 1 Staphylococcus haemolytic protein DUF3357 PF11837.3 CBZ27213.1 - 0.11 12.3 0.2 0.11 12.3 0.2 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) Mucin PF01456.12 CBZ27213.1 - 0.29 10.8 4.7 1.6 8.4 0.5 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Shisa PF13908.1 CBZ27213.1 - 1.9 8.6 0.0 1.9 8.6 0.0 3.0 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Med15 PF09606.5 CBZ27213.1 - 2.6 6.1 16.7 3.2 5.8 11.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DIM1 PF02966.11 CBZ27214.1 - 5.4e-31 106.8 0.2 5.9e-27 93.7 0.1 2.1 2 0 0 2 2 2 2 Mitosis protein DIM1 GFO_IDH_MocA PF01408.17 CBZ27216.1 - 2.2e-15 57.2 0.1 3.7e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PriCT_2 PF08707.6 CBZ27217.1 - 6e-17 61.2 2.0 6e-17 61.2 1.4 1.9 2 0 0 2 2 2 1 Primase C terminal 2 (PriCT-2) DNA_primase_S PF01896.14 CBZ27217.1 - 0.0067 16.2 0.0 0.021 14.6 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Thiolase_C PF02803.13 CBZ27218.1 - 1.5e-12 46.9 0.1 9e-11 41.2 0.1 2.5 1 1 1 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 CBZ27218.1 - 5.2e-09 35.4 3.1 2.7e-08 33.1 0.6 2.6 2 1 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 CBZ27218.1 - 2.5e-07 30.4 0.9 5e-07 29.4 0.2 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CBZ27218.1 - 0.011 15.3 1.4 0.3 10.7 0.8 2.6 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.17 CBZ27218.1 - 5 6.9 6.9 11 5.9 0.0 3.5 3 1 0 4 4 4 0 Beta-ketoacyl synthase, C-terminal domain COX17 PF05051.8 CBZ27219.1 - 1.3e-05 25.0 0.3 2.1e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) AMP-binding PF00501.23 CBZ27220.1 - 1.1e-87 294.1 0.2 1.4e-87 293.8 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ27220.1 - 3.1e-16 60.0 0.2 7.6e-16 58.8 0.2 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.17 CBZ27221.1 - 6.6e-12 44.8 0.0 1.1e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27221.1 - 2.9e-09 36.7 0.0 1e-08 34.9 0.0 2.0 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27221.1 - 1.6e-07 31.0 0.0 2.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ27222.1 - 3.6e-13 48.9 0.0 5.7e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27222.1 - 9.6e-07 28.6 0.0 1.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27222.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.18 CBZ27223.1 - 6.8e-10 38.9 0.0 1.5e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBZ27223.1 - 2.5e-05 24.1 0.3 0.00011 22.0 0.1 1.9 1 1 1 2 2 2 1 Dynamin family AAA_29 PF13555.1 CBZ27223.1 - 0.00085 18.7 0.0 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 CBZ27223.1 - 0.00095 18.3 0.0 0.0019 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBZ27223.1 - 0.0024 17.3 0.0 1.1 8.7 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBZ27223.1 - 0.031 13.5 0.0 0.057 12.6 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B T2SE PF00437.15 CBZ27223.1 - 0.049 12.5 0.0 0.68 8.7 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Parvo_NS1 PF01057.12 CBZ27223.1 - 0.067 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 CBZ27223.1 - 0.093 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 CBZ27223.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1738 PF08401.6 CBZ27225.1 - 0.00021 21.0 1.7 0.094 12.4 0.2 3.2 2 1 1 3 3 3 2 Domain of unknown function (DUF1738) DUF676 PF05057.9 CBZ27227.1 - 1.3e-12 47.4 0.0 3.3e-10 39.6 0.0 2.7 2 1 0 2 2 2 2 Putative serine esterase (DUF676) SET PF00856.23 CBZ27228.1 - 5.5e-13 49.5 3.9 1.1e-08 35.5 0.3 3.3 3 0 0 3 3 3 2 SET domain zf-MYND PF01753.13 CBZ27228.1 - 0.00012 21.9 3.9 0.00012 21.9 2.7 3.3 5 0 0 5 5 5 1 MYND finger zf-Mss51 PF13824.1 CBZ27228.1 - 0.015 15.1 1.9 0.044 13.6 1.3 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Adeno_terminal PF02459.10 CBZ27228.1 - 0.032 12.4 2.5 0.046 11.8 1.7 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Peptidase_C2 PF00648.16 CBZ27229.1 - 0.095 11.6 0.1 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Calpain family cysteine protease FAD-oxidase_C PF02913.14 CBZ27230.1 - 7.5e-47 159.7 0.0 1.4e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CBZ27230.1 - 7.4e-31 106.4 0.4 1.8e-30 105.2 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain SET PF00856.23 CBZ27231.1 - 1.3e-08 35.3 0.0 3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 CBZ27231.1 - 5.3 7.0 16.7 0.38 10.6 7.3 2.4 2 0 0 2 2 2 0 MYND finger Na_H_Exchanger PF00999.16 CBZ27232.1 - 8.9e-46 156.1 44.4 1.2e-45 155.7 30.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF730 PF05325.6 CBZ27233.1 - 0.18 11.5 0.1 0.58 9.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF730) LSR PF05624.9 CBZ27233.1 - 9.4 6.0 15.0 0.36 10.5 5.5 2.1 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) TPR_19 PF14559.1 CBZ27235.1 - 0.0021 18.3 0.1 5.2 7.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Cornifin PF02389.10 CBZ27235.1 - 0.0032 17.2 4.9 0.0074 16.0 3.4 1.5 1 0 0 1 1 1 1 Cornifin (SPRR) family CO_deh_flav_C PF03450.12 CBZ27235.1 - 0.0071 16.2 2.4 2.4 8.1 0.2 3.1 2 0 0 2 2 2 2 CO dehydrogenase flavoprotein C-terminal domain TPR_17 PF13431.1 CBZ27235.1 - 0.0097 16.0 0.1 0.25 11.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ27235.1 - 0.076 12.9 1.5 2.2 8.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ27235.1 - 0.38 11.5 0.1 0.38 11.5 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat ADH_zinc_N_2 PF13602.1 CBZ27236.1 - 5e-14 53.2 0.1 2.5e-13 51.0 0.0 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CBZ27236.1 - 4e-10 39.3 0.1 1.9e-08 33.9 0.0 2.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CBZ27236.1 - 4.6e-09 36.0 0.4 1.9e-08 34.0 0.1 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_32N PF00251.15 CBZ27237.1 - 7.1e-91 304.7 1.4 8.1e-91 304.5 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.9 CBZ27237.1 - 5.9e-05 22.2 0.1 0.00011 21.4 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 BNR_2 PF13088.1 CBZ27237.1 - 0.023 14.0 1.2 0.041 13.1 0.8 1.4 1 0 0 1 1 1 0 BNR repeat-like domain Methyltransf_28 PF02636.12 CBZ27238.1 - 2.2e-59 200.9 0.0 2.9e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NIF PF03031.13 CBZ27239.1 - 0.037 13.6 0.0 0.097 12.3 0.0 1.6 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Peptidase_M17 PF00883.16 CBZ27242.1 - 5e-100 334.3 0.0 6.4e-100 334.0 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 CBZ27242.1 - 3.8e-06 26.6 0.2 3.8e-05 23.4 0.0 2.5 2 1 1 3 3 3 1 Cytosol aminopeptidase family, N-terminal domain CHB_HEX_C_1 PF13290.1 CBZ27243.1 - 8.1e-07 28.7 0.5 0.00059 19.5 0.1 3.4 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C PF03174.8 CBZ27243.1 - 3.9e-05 23.4 0.2 0.0074 16.0 0.1 3.4 4 0 0 4 4 4 1 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 CBZ27243.1 - 0.00019 21.4 0.2 0.35 11.0 0.0 3.5 3 0 0 3 3 3 2 Fn3 associated Adeno_E3_CR2 PF02439.10 CBZ27243.1 - 0.11 12.0 1.0 0.22 11.0 0.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ICEA PF05315.6 CBZ27245.1 - 0.015 14.5 1.4 0.029 13.6 0.1 1.9 2 0 0 2 2 2 0 ICEA Protein ALIX_LYPXL_bnd PF13949.1 CBZ27247.1 - 0.0049 15.8 1.5 0.0086 15.0 1.0 1.4 1 1 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF641 PF04859.7 CBZ27247.1 - 0.026 14.2 2.7 0.16 11.7 0.4 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) HeLo PF14479.1 CBZ27247.1 - 0.081 12.6 2.7 0.12 12.0 0.9 1.9 1 1 0 2 2 2 0 Prion-inhibition and propagation OmpH PF03938.9 CBZ27247.1 - 0.092 12.6 2.1 0.07 13.0 0.5 1.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3510 PF12022.3 CBZ27247.1 - 0.4 10.8 9.9 0.7 9.9 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3510) DUF4463 PF14703.1 CBZ27247.1 - 0.71 10.4 4.6 44 4.7 2.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) U79_P34 PF03064.11 CBZ27250.1 - 3.3 7.1 7.8 3.2 7.1 5.4 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 LEA_4 PF02987.11 CBZ27251.1 - 0.00037 20.2 0.3 0.00053 19.7 0.2 1.4 1 1 0 1 1 1 1 Late embryogenesis abundant protein YtxH PF12732.2 CBZ27251.1 - 0.0048 17.2 0.9 0.0059 16.9 0.6 1.1 1 0 0 1 1 1 1 YtxH-like protein DUF883 PF05957.8 CBZ27251.1 - 0.021 15.2 0.1 0.024 15.0 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.5 CBZ27251.1 - 0.17 11.8 0.7 2.3 8.2 0.3 1.8 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) FlgM PF04316.8 CBZ27251.1 - 0.26 11.2 1.4 9.6 6.2 0.1 2.2 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM LEA_4 PF02987.11 CBZ27253.1 - 0.00037 20.2 0.3 0.00053 19.7 0.2 1.4 1 1 0 1 1 1 1 Late embryogenesis abundant protein YtxH PF12732.2 CBZ27253.1 - 0.0048 17.2 0.9 0.0059 16.9 0.6 1.1 1 0 0 1 1 1 1 YtxH-like protein DUF883 PF05957.8 CBZ27253.1 - 0.021 15.2 0.1 0.024 15.0 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Tape_meas_lam_C PF09718.5 CBZ27253.1 - 0.17 11.8 0.7 2.3 8.2 0.3 1.8 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) FlgM PF04316.8 CBZ27253.1 - 0.26 11.2 1.4 9.6 6.2 0.1 2.2 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM KIAA1430 PF13879.1 CBZ27255.1 - 0.0013 19.0 0.8 0.0028 18.0 0.5 1.6 1 0 0 1 1 1 1 KIAA1430 homologue PI31_Prot_C PF08577.6 CBZ27255.1 - 5.5 7.7 11.3 1.4 9.6 4.8 2.2 2 0 0 2 2 2 0 PI31 proteasome regulator 5-FTHF_cyc-lig PF01812.15 CBZ27257.1 - 3.7e-13 49.6 0.5 2.4e-09 37.2 0.0 3.3 3 1 0 3 3 3 2 5-formyltetrahydrofolate cyclo-ligase family Adeno_E1B_55K_N PF04623.7 CBZ27257.1 - 0.046 14.2 0.0 0.3 11.5 0.0 2.4 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus HIT PF01230.18 CBZ27258.1 - 1.1e-10 41.9 0.0 2.7e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CBZ27258.1 - 0.00014 22.0 0.2 0.0016 18.6 0.1 2.3 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2410 PF10307.4 CBZ27259.1 - 1.1e-06 28.1 0.0 6.4e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Hypothetical protein (DUF2410) DUF3321 PF11968.3 CBZ27260.1 - 0.17 11.5 0.4 0.7 9.4 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase (DUF3321) LRR_4 PF12799.2 CBZ27261.1 - 5.3e-22 76.9 9.6 2.9e-05 23.5 0.0 7.7 4 2 1 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ27261.1 - 9.2e-09 34.9 18.5 0.075 12.7 0.1 6.9 3 2 4 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 CBZ27261.1 - 4.1e-05 23.0 12.4 9 6.7 0.0 8.4 7 3 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.1 CBZ27261.1 - 8.7e-05 22.2 13.4 14 6.1 0.0 9.0 9 2 1 10 10 10 1 Leucine Rich repeat LRR_7 PF13504.1 CBZ27261.1 - 0.0044 16.9 20.6 19 6.0 0.0 8.5 9 1 0 9 9 9 1 Leucine rich repeat LRR_5 PF13306.1 CBZ27261.1 - 0.013 15.1 3.8 0.93 9.2 0.0 3.4 2 1 2 4 4 4 0 Leucine rich repeats (6 copies) DUF3184 PF11380.3 CBZ27262.1 - 0.00075 17.5 0.6 0.0099 13.8 0.0 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CBZ27263.1 - 0.0014 16.7 0.1 0.015 13.2 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3184) CH PF00307.26 CBZ27264.1 - 0.0015 18.5 0.4 0.012 15.6 0.3 2.2 1 1 0 1 1 1 1 Calponin homology (CH) domain DUF3450 PF11932.3 CBZ27265.1 - 0.0053 16.0 4.8 0.0053 16.0 3.3 4.8 4 1 0 5 5 5 2 Protein of unknown function (DUF3450) DUF972 PF06156.8 CBZ27265.1 - 1.9 8.8 26.1 0.55 10.5 1.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 CBZ27265.1 - 2.3 7.3 8.4 1.3 8.1 0.4 3.3 3 0 0 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 CBZ27265.1 - 2.7 7.5 36.7 0.22 11.1 4.0 4.5 4 0 0 4 4 4 0 IncA protein HALZ PF02183.13 CBZ27265.1 - 3.2 7.5 12.2 0.32 10.7 0.8 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper GAS PF13851.1 CBZ27265.1 - 3.9 6.6 28.8 1.3 8.1 1.6 4.1 4 1 0 4 4 4 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 CBZ27265.1 - 10 5.7 31.7 0.11 11.9 1.5 5.6 5 1 0 5 5 5 0 Septum formation initiator IncA PF04156.9 CBZ27266.1 - 0.0038 16.8 17.5 0.0038 16.8 12.1 6.2 1 1 4 6 6 6 3 IncA protein Pox_A_type_inc PF04508.7 CBZ27266.1 - 0.093 12.5 0.1 0.093 12.5 0.1 6.3 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat HALZ PF02183.13 CBZ27266.1 - 0.5 10.1 32.2 0.24 11.1 0.6 7.3 7 1 1 8 8 8 0 Homeobox associated leucine zipper DUF948 PF06103.6 CBZ27266.1 - 6 6.8 18.8 0.99 9.3 0.2 4.8 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.6 CBZ27266.1 - 8.3 3.8 19.7 0.43 8.0 9.2 2.1 2 1 0 2 2 2 0 Prominin BRCA-2_OB3 PF09104.5 CBZ27267.1 - 0.0012 18.6 0.5 0.013 15.3 0.1 2.3 1 1 1 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 DUF2765 PF10963.3 CBZ27267.1 - 0.024 14.5 0.1 0.089 12.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2765) Prominin PF05478.6 CBZ27267.1 - 0.46 7.9 8.5 0.068 10.6 0.8 2.3 1 1 0 2 2 2 0 Prominin DUF4061 PF13270.1 CBZ27267.1 - 1.7 8.7 7.2 2.7 8.1 0.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) Amdo_NSP PF12475.3 CBZ27268.1 - 0.64 9.9 3.1 11 6.0 0.1 3.3 3 1 1 4 4 4 0 Amdovirus non-structural protein DUF1900 PF08954.6 CBZ27269.1 - 2e-37 127.7 0.0 3.4e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 CBZ27269.1 - 2e-12 46.4 2.4 0.00017 21.3 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 CBZ27269.1 - 3.3e-07 29.8 0.0 5.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Ribosomal_S9 PF00380.14 CBZ27270.1 - 0.0002 21.5 0.0 0.00039 20.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 IGR PF09597.5 CBZ27270.1 - 0.11 12.3 0.2 13 5.7 0.1 2.4 2 0 0 2 2 2 0 IGR protein motif UPF0546 PF10639.4 CBZ27271.1 - 1.1e-15 57.3 1.6 3.6e-15 55.7 0.2 1.9 1 1 1 2 2 2 1 Uncharacterised protein family UPF0546 His_Phos_2 PF00328.17 CBZ27272.1 - 2.9e-25 89.3 0.1 8.6e-25 87.7 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Methyltransf_5 PF01795.14 CBZ27273.1 - 3.8e-30 105.2 0.0 5.4e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family Methyltransf_26 PF13659.1 CBZ27273.1 - 6.2e-06 26.2 0.1 3.1e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ27273.1 - 0.0004 19.9 0.0 0.0076 15.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CBZ27273.1 - 0.01 15.1 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_18 PF12847.2 CBZ27273.1 - 0.019 15.5 0.0 0.44 11.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain SIR2 PF02146.12 CBZ27274.1 - 4e-35 121.1 0.1 6.8e-34 117.1 0.0 2.1 1 1 0 1 1 1 1 Sir2 family PHF5 PF03660.9 CBZ27274.1 - 0.017 15.1 0.6 0.061 13.3 0.0 2.2 3 0 0 3 3 3 0 PHF5-like protein Cpn60_TCP1 PF00118.19 CBZ27275.1 - 5.7e-150 500.1 2.9 6.5e-150 499.9 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Spore_coat_CotO PF14153.1 CBZ27276.1 - 0.029 13.8 0.3 0.035 13.5 0.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO PPR_2 PF13041.1 CBZ27277.1 - 9.2e-07 28.7 0.1 1.5e-05 24.8 0.0 2.1 2 1 1 3 3 3 2 PPR repeat family PPR_1 PF12854.2 CBZ27277.1 - 1.4e-05 24.5 0.0 3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 PPR repeat PPR_3 PF13812.1 CBZ27277.1 - 0.00034 20.6 0.0 0.0015 18.6 0.0 2.3 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.15 CBZ27277.1 - 0.00038 20.2 0.5 0.0013 18.5 0.1 2.2 2 0 0 2 2 2 1 PPR repeat DUF3250 PF11618.3 CBZ27278.1 - 3.6e-31 107.5 0.6 3.6e-31 107.5 0.4 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF3250) DUF972 PF06156.8 CBZ27278.1 - 0.36 11.1 29.7 0.59 10.4 0.2 4.9 2 1 1 4 4 4 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 CBZ27278.1 - 4.6 7.5 6.6 5.5 7.3 0.3 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein RICTOR_M PF14666.1 CBZ27279.1 - 2.2e-56 190.4 0.0 1.2e-55 188.0 0.0 2.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.1 CBZ27279.1 - 1.1e-14 53.8 1.1 3.8e-12 45.4 0.0 2.7 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.1 CBZ27279.1 - 1.4e-08 34.7 0.3 7.3e-08 32.3 0.2 2.3 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 CBZ27279.1 - 0.0023 17.8 0.2 0.045 13.6 0.0 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF4455 PF14643.1 CBZ27279.1 - 0.19 10.3 2.3 0.29 9.7 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) XPG_I PF00867.13 CBZ27282.1 - 6.2e-22 77.4 0.2 8.6e-19 67.3 0.1 2.8 2 0 0 2 2 2 2 XPG I-region XPG_N PF00752.12 CBZ27282.1 - 2.8e-14 53.1 0.0 2.7e-06 27.5 0.0 2.6 3 0 0 3 3 3 2 XPG N-terminal domain FA_hydroxylase PF04116.8 CBZ27285.1 - 4.1e-13 49.7 22.3 4.1e-13 49.7 15.5 2.7 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily DUF1673 PF07895.6 CBZ27285.1 - 4.7 6.6 8.5 0.25 10.8 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Dynein_heavy PF03028.10 CBZ27286.1 - 1.1e-198 661.7 0.0 2.8e-198 660.3 0.0 1.8 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ27286.1 - 6.4e-127 423.4 5.4 6.4e-127 423.4 3.7 4.5 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ27286.1 - 1.4e-96 322.5 0.0 4.8e-96 320.7 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N1 PF08385.7 CBZ27286.1 - 9.5e-82 275.2 7.2 2.8e-81 273.6 0.0 4.3 3 2 0 3 3 2 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.2 CBZ27286.1 - 1.1e-65 221.2 0.0 3.1e-65 219.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ27286.1 - 5e-51 172.7 0.4 1.5e-50 171.2 0.1 1.9 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBZ27286.1 - 1.4e-47 162.0 0.1 3.5e-47 160.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CBZ27286.1 - 1.8e-41 142.0 15.8 3.6e-41 141.0 11.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ27286.1 - 3.5e-25 88.3 0.0 3.9e-07 29.8 0.0 5.7 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ27286.1 - 6.5e-06 26.3 0.1 0.36 11.0 0.0 4.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ27286.1 - 0.00057 20.7 0.3 5.2 7.9 0.0 5.0 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 CBZ27286.1 - 0.0016 18.6 7.9 0.61 10.2 0.0 6.1 6 0 0 6 6 6 1 AAA domain AAA_18 PF13238.1 CBZ27286.1 - 0.0073 16.6 1.4 19 5.5 0.0 4.7 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.17 CBZ27286.1 - 0.017 15.2 0.1 7.1 6.8 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_19 PF13245.1 CBZ27286.1 - 0.39 10.5 7.0 3.7 7.3 0.4 3.4 3 0 0 3 3 3 0 Part of AAA domain SBP_bac_1 PF01547.20 CBZ27286.1 - 3.7 7.1 0.1 7.2 6.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein YceI PF04264.8 CBZ27287.1 - 7.3e-10 39.0 0.0 8.7e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 YceI-like domain DNA_pol_B PF00136.16 CBZ27288.1 - 3e-77 260.3 0.0 4.3e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.1 CBZ27288.1 - 0.00016 21.6 0.1 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.14 CBZ27288.1 - 0.0003 19.7 0.0 0.23 10.2 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain Radical_SAM PF04055.16 CBZ27290.1 - 9.2e-15 55.1 0.0 2.5e-14 53.8 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CBZ27290.1 - 6.6e-09 35.6 0.5 1.6e-08 34.4 0.3 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Hum_adeno_E3A PF05393.6 CBZ27291.1 - 0.18 11.4 0.1 0.34 10.5 0.1 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Mito_carr PF00153.22 CBZ27292.1 - 1.5e-36 123.9 0.6 3.4e-15 55.5 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Helicase_C PF00271.26 CBZ27293.1 - 4.9e-12 45.5 0.0 9.1e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ27293.1 - 1.2e-11 44.3 0.0 4.1e-10 39.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase HHH_5 PF14520.1 CBZ27293.1 - 0.00021 21.3 0.2 0.00077 19.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain Mog1 PF04603.7 CBZ27295.1 - 1.8e-24 86.2 0.0 4.4e-22 78.5 0.0 2.3 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Fer2_3 PF13085.1 CBZ27297.1 - 2.5e-31 107.7 0.2 6.4e-31 106.4 0.0 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 CBZ27297.1 - 0.0032 17.1 0.7 0.01 15.5 0.5 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain TPR_21 PF09976.4 CBZ27297.1 - 0.0049 16.8 1.8 0.0095 15.8 1.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ27297.1 - 0.025 14.9 2.0 0.025 14.9 1.4 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Acetone_carb_G PF08882.6 CBZ27297.1 - 0.051 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit TPR_14 PF13428.1 CBZ27297.1 - 0.077 13.6 2.2 0.11 13.1 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ27297.1 - 0.14 12.7 1.4 0.36 11.3 1.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ27297.1 - 0.42 11.1 2.8 0.28 11.7 0.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-DHHC PF01529.15 CBZ27298.1 - 1.1e-32 112.8 15.0 1.1e-32 112.8 10.4 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF1282 PF06930.7 CBZ27298.1 - 0.96 9.0 12.3 0.34 10.5 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) zf-DHHC PF01529.15 CBZ27299.1 - 2.7e-36 124.5 1.2 2.7e-36 124.5 0.8 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase zf-DHHC PF01529.15 CBZ27300.1 - 5.1e-22 78.0 24.8 6.3e-22 77.7 15.0 2.5 1 1 1 2 2 2 1 DHHC palmitoyltransferase PTPlike_phytase PF14566.1 CBZ27301.1 - 1.1e-106 353.2 0.3 9.8e-40 136.0 0.0 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CBZ27301.1 - 0.0012 19.1 0.2 3.1 8.0 0.0 3.0 2 0 0 2 2 2 2 Tyrosine phosphatase family ADK PF00406.17 CBZ27302.1 - 9.3e-08 32.0 0.0 0.0065 16.3 0.0 2.4 2 1 0 2 2 2 2 Adenylate kinase AAA_19 PF13245.1 CBZ27302.1 - 5.8e-05 22.7 0.2 0.00028 20.5 0.2 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CBZ27302.1 - 0.00022 21.1 0.0 0.00071 19.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ27302.1 - 0.0011 19.0 0.0 0.0028 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ27302.1 - 0.0027 18.5 0.0 0.0062 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ27302.1 - 0.0033 17.4 0.8 0.008 16.1 0.2 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 CBZ27302.1 - 0.0036 17.5 0.1 0.019 15.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CBZ27302.1 - 0.0064 15.5 0.1 0.017 14.2 0.1 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 CBZ27302.1 - 0.0071 16.4 0.1 0.044 13.9 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.1 CBZ27302.1 - 0.0079 15.6 0.1 0.052 12.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBZ27302.1 - 0.025 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KTI12 PF08433.5 CBZ27302.1 - 0.027 13.6 0.1 0.099 11.8 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 CBZ27302.1 - 0.046 12.8 0.1 0.083 12.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CBZ27302.1 - 0.05 13.2 0.0 0.38 10.3 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 CBZ27302.1 - 0.071 13.4 0.0 0.48 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 CBZ27302.1 - 0.096 11.6 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 RNA_helicase PF00910.17 CBZ27302.1 - 0.098 12.8 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.10 CBZ27302.1 - 0.5 8.9 1.7 0.61 8.6 0.1 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Methyltransf_26 PF13659.1 CBZ27303.1 - 0.0019 18.2 0.6 0.0036 17.3 0.4 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ27303.1 - 0.038 14.3 0.0 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain B9-C2 PF07162.6 CBZ27304.1 - 8.6e-25 87.4 0.0 1.7e-24 86.4 0.0 1.5 2 0 0 2 2 2 1 Ciliary basal body-associated, B9 protein zf-rbx1 PF12678.2 CBZ27307.1 - 1.1e-12 47.8 3.9 1.9e-12 47.0 2.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CBZ27307.1 - 3.9e-10 39.3 10.2 9.8e-09 34.9 7.0 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ27307.1 - 8.3e-07 28.5 5.0 1.7e-06 27.5 3.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ27307.1 - 2.2e-06 27.5 7.0 5.4e-06 26.3 3.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ27307.1 - 1.3e-05 24.8 5.0 3.2e-05 23.5 3.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBZ27307.1 - 0.00024 20.8 4.9 0.00066 19.4 3.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CBZ27307.1 - 0.00065 19.3 9.9 0.0028 17.3 6.1 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CBZ27307.1 - 0.13 11.7 3.9 0.14 11.7 1.7 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 CBZ27307.1 - 1.2 9.2 7.3 0.43 10.6 3.0 1.8 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.3 CBZ27307.1 - 1.7 8.6 6.0 4.5 7.3 2.9 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain V-SNARE PF05008.10 CBZ27308.1 - 6e-08 32.7 0.3 2e-05 24.6 0.0 3.2 3 1 1 4 4 4 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 CBZ27308.1 - 8.4e-06 25.3 1.4 1.9e-05 24.2 0.1 2.0 2 0 0 2 2 2 1 Sec20 V-SNARE_C PF12352.3 CBZ27308.1 - 0.004 17.1 3.0 0.004 17.1 2.1 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.6 CBZ27308.1 - 0.025 14.9 1.7 2.3 8.6 0.0 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF3391 PF11871.3 CBZ27308.1 - 0.065 13.4 1.9 1.6 8.9 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) DUF1664 PF07889.7 CBZ27308.1 - 0.24 11.1 1.5 3.3 7.5 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Laminin_I PF06008.9 CBZ27308.1 - 0.3 10.3 6.4 0.26 10.5 2.6 1.9 2 0 0 2 2 2 0 Laminin Domain I BRE1 PF08647.6 CBZ27308.1 - 0.34 10.9 2.3 2.1 8.3 0.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase V-SNARE PF05008.10 CBZ27309.1 - 9.6e-12 44.8 0.4 7.7e-11 41.9 0.0 2.6 2 2 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 CBZ27309.1 - 4.4e-07 29.8 1.8 6.1e-07 29.4 0.6 1.7 2 0 0 2 2 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CBZ27309.1 - 2.6e-05 23.8 3.9 2.8e-05 23.7 1.2 2.1 2 1 1 3 3 3 1 Sec20 Unstab_antitox PF09720.5 CBZ27309.1 - 0.0008 19.0 0.1 0.0022 17.6 0.1 1.8 1 0 0 1 1 1 1 Putative addiction module component CCDC155 PF14662.1 CBZ27309.1 - 0.0019 17.8 6.6 0.059 12.9 0.7 2.3 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 DUF4140 PF13600.1 CBZ27309.1 - 0.014 15.8 1.5 0.014 15.8 1.1 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) GCR PF02155.10 CBZ27309.1 - 0.031 13.0 0.1 0.038 12.7 0.0 1.3 1 0 0 1 1 1 0 Glucocorticoid receptor Baculo_11_kDa PF06143.6 CBZ27309.1 - 0.036 13.4 0.7 0.069 12.5 0.5 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family HXXSHH PF07586.6 CBZ27309.1 - 0.039 12.8 4.2 0.031 13.2 0.5 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1552) DUF2142 PF09913.4 CBZ27309.1 - 0.077 11.6 0.7 0.11 11.1 0.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2142) TMEM154 PF15102.1 CBZ27309.1 - 0.17 11.5 3.9 0.29 10.8 2.7 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF883 PF05957.8 CBZ27309.1 - 0.18 12.2 11.3 0.72 10.2 2.3 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) ATP-synt_8 PF00895.15 CBZ27309.1 - 0.2 11.8 1.3 0.37 11.0 0.9 1.4 1 0 0 1 1 1 0 ATP synthase protein 8 Muted PF14942.1 CBZ27309.1 - 0.22 11.3 5.1 0.42 10.4 0.2 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF1515 PF07439.6 CBZ27309.1 - 0.32 10.8 3.5 0.19 11.5 0.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) ODV-E18 PF10717.4 CBZ27309.1 - 0.32 10.4 1.7 0.63 9.5 1.2 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 OapA_N PF08525.6 CBZ27309.1 - 1.7 8.5 6.2 18 5.2 4.6 2.2 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif BRCT PF00533.21 CBZ27310.1 - 0.0039 17.3 0.0 0.0094 16.0 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain EXOSC1 PF10447.4 CBZ27311.1 - 9.4e-10 38.3 0.0 1.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 TRAM PF01938.15 CBZ27311.1 - 0.11 12.2 0.2 0.62 9.8 0.0 2.1 3 0 0 3 3 3 0 TRAM domain Trichoplein PF13868.1 CBZ27313.1 - 1.5e-13 49.9 125.6 1.5e-13 49.9 87.0 2.2 2 0 0 2 2 2 1 Tumour suppressor, Mitostatin Semialdhyde_dh PF01118.19 CBZ27313.1 - 6.3 7.1 6.8 3.7 7.8 0.9 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TIP41 PF04176.8 CBZ27314.1 - 2.4e-18 66.0 0.0 4.1e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 TIP41-like family GAF_2 PF13185.1 CBZ27314.1 - 1.1e-06 29.2 0.0 2.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 CBZ27314.1 - 9e-06 25.8 0.1 2.2e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.1 CBZ27314.1 - 0.00041 20.4 0.0 0.00082 19.4 0.0 1.4 1 0 0 1 1 1 1 GAF domain LRR_4 PF12799.2 CBZ27315.1 - 5.7e-06 25.8 0.8 0.011 15.3 0.0 3.0 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ27315.1 - 0.0024 17.5 0.2 0.99 9.2 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 CBZ27315.1 - 0.2 11.8 2.2 4.7 7.5 0.0 3.5 4 1 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 CBZ27315.1 - 0.23 11.7 3.7 11 6.7 0.0 4.2 4 2 2 6 6 6 0 Leucine rich repeat Nop14 PF04147.7 CBZ27315.1 - 4.6 5.0 12.4 5.2 4.8 8.6 1.0 1 0 0 1 1 1 0 Nop14-like family Ala_racemase_N PF01168.15 CBZ27316.1 - 9.6e-41 139.7 0.0 1.2e-40 139.4 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LRR_4 PF12799.2 CBZ27317.1 - 2.6e-12 46.0 10.1 0.00062 19.3 0.2 5.4 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ27317.1 - 1.1e-11 44.3 7.6 0.0045 16.7 0.4 4.7 3 2 1 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 CBZ27317.1 - 1.5e-09 36.5 7.0 0.2 11.8 0.1 7.1 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.1 CBZ27317.1 - 1.8e-05 24.3 9.5 0.44 10.7 0.1 6.0 5 1 1 6 6 6 2 Leucine Rich repeat LRR_7 PF13504.1 CBZ27317.1 - 0.076 13.2 19.3 5.9 7.5 0.2 6.7 7 1 0 7 7 7 0 Leucine rich repeat Co_AT_N PF12557.3 CBZ27317.1 - 0.12 12.2 0.9 0.22 11.4 0.6 1.4 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal V_ATPase_I PF01496.14 CBZ27319.1 - 1.6e-219 730.6 11.3 2.7e-203 676.9 6.3 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family BCDHK_Adom3 PF10436.4 CBZ27319.1 - 0.016 14.7 0.2 0.033 13.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase FIST_C PF10442.4 CBZ27319.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 FIST C domain DUF948 PF06103.6 CBZ27319.1 - 0.15 11.9 0.6 18 5.2 0.1 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF972 PF06156.8 CBZ27319.1 - 0.23 11.8 2.5 0.54 10.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF972) AAA_27 PF13514.1 CBZ27319.1 - 0.91 7.1 5.3 0.31 8.6 0.3 1.9 2 0 0 2 2 2 0 AAA domain DegS PF05384.6 CBZ27319.1 - 3.7 6.7 8.6 4.6 6.4 0.5 2.9 2 1 1 3 3 3 0 Sensor protein DegS UbiA PF01040.13 CBZ27320.1 - 1.3e-28 99.9 21.7 1.4e-28 99.7 14.7 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family NFRKB_winged PF14465.1 CBZ27322.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 NFRKB Winged Helix-like NRDE-2 PF08424.5 CBZ27323.1 - 2.2e-07 30.0 1.0 0.00096 18.1 0.1 3.2 2 1 1 3 3 3 3 NRDE-2, necessary for RNA interference Beach PF02138.13 CBZ27325.1 - 8.3e-86 287.7 0.0 1.1e-85 287.3 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PQQ_2 PF13360.1 CBZ27325.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 PQQ-like domain Nuc_deoxyrib_tr PF05014.10 CBZ27326.1 - 1.5e-26 92.4 0.0 2e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DUF4406 PF14359.1 CBZ27326.1 - 0.039 14.0 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) BCDHK_Adom3 PF10436.4 CBZ27327.1 - 2.8e-33 114.7 0.0 4.7e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CBZ27327.1 - 0.022 14.4 0.0 0.077 12.7 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FerB PF08150.7 CBZ27327.1 - 0.084 12.9 0.0 7.5 6.7 0.0 2.4 2 0 0 2 2 2 0 FerB (NUC096) domain ANTH PF07651.11 CBZ27328.1 - 1.2e-25 89.8 0.4 1.8e-25 89.2 0.3 1.3 1 1 0 1 1 1 1 ANTH domain ENTH PF01417.15 CBZ27328.1 - 0.014 15.2 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 ENTH domain Ribosomal_L22 PF00237.14 CBZ27330.1 - 2.7e-30 104.4 0.2 3.3e-30 104.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4616 PF15394.1 CBZ27331.1 - 0.041 12.9 0.0 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) DnaJ PF00226.26 CBZ27333.1 - 0.031 14.0 0.0 0.08 12.6 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain zf-RING_2 PF13639.1 CBZ27334.1 - 3.1e-10 39.7 4.5 3.1e-10 39.7 3.1 4.8 5 1 0 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ27334.1 - 3.1e-05 23.5 2.1 3.1e-05 23.5 1.5 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ27334.1 - 6.5e-05 22.8 2.3 6.5e-05 22.8 1.6 4.3 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ27334.1 - 0.00013 22.0 1.0 0.00013 22.0 0.7 3.0 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CBZ27334.1 - 0.0017 18.0 0.5 0.0046 16.6 0.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CBZ27334.1 - 0.0019 17.8 4.5 0.0019 17.8 3.1 4.6 4 1 1 5 5 5 1 zinc-RING finger domain Baculo_RING PF05883.6 CBZ27334.1 - 0.44 10.3 2.9 0.57 10.0 0.3 2.2 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF3592 PF12158.3 CBZ27335.1 - 7.8e-05 22.4 0.2 0.00011 22.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Enkurin PF13864.1 CBZ27336.1 - 3.3e-22 78.5 3.8 4.8e-22 78.0 2.6 1.2 1 0 0 1 1 1 1 Calmodulin-binding DUF3367 PF11847.3 CBZ27336.1 - 0.042 11.7 0.0 0.06 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) CK2S PF15011.1 CBZ27336.1 - 0.1 12.3 1.5 3 7.6 0.1 2.1 1 1 1 2 2 2 0 Casein Kinase 2 substrate PARP_regulatory PF01358.13 CBZ27337.1 - 2e-16 59.5 0.0 2.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit UPF0182 PF03699.8 CBZ27337.1 - 0.064 11.1 0.0 0.089 10.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) WD40 PF00400.27 CBZ27338.1 - 2.1e-09 36.8 15.8 0.0021 17.8 0.5 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Ank_2 PF12796.2 CBZ27339.1 - 3.8e-44 148.9 7.6 8.9e-16 58.0 0.6 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ27339.1 - 6e-40 133.1 4.4 8.3e-09 34.8 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 CBZ27339.1 - 1.7e-31 107.5 4.6 1.1e-09 38.1 0.1 4.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBZ27339.1 - 2.5e-30 104.3 5.7 2.2e-07 31.1 0.0 5.1 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ27339.1 - 1.2e-24 83.8 4.4 0.001 19.0 0.0 7.4 8 0 0 8 8 8 6 Ankyrin repeat TPR_11 PF13414.1 CBZ27339.1 - 1.2e-18 66.5 4.2 3.9e-14 52.0 0.4 2.8 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBZ27339.1 - 2.7e-09 36.2 2.5 0.0075 15.8 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ27339.1 - 2.6e-06 26.9 5.7 0.11 12.4 0.0 4.0 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ27339.1 - 4.4e-05 23.3 1.6 0.41 10.9 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ27339.1 - 0.00068 19.7 1.4 0.0019 18.2 1.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBZ27339.1 - 0.0071 16.1 0.1 0.15 11.8 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat PEX11 PF05648.9 CBZ27340.1 - 1.6e-10 40.6 1.0 1.6e-06 27.5 0.0 2.1 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) PalH PF08733.5 CBZ27340.1 - 0.06 12.1 0.0 0.076 11.8 0.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 Phosducin PF02114.11 CBZ27342.1 - 9.3e-07 27.8 0.0 1.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Phosducin MRC1 PF09444.5 CBZ27342.1 - 0.012 15.8 0.2 0.02 15.2 0.1 1.3 1 0 0 1 1 1 0 MRC1-like domain Cas_GSU0054 PF09609.5 CBZ27342.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) EF-1_beta_acid PF10587.4 CBZ27342.1 - 0.3 11.2 3.5 1.5 8.9 2.4 2.3 1 1 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Snurportin1 PF11538.3 CBZ27342.1 - 0.83 9.4 3.2 0.98 9.2 1.0 2.0 2 0 0 2 2 2 0 Snurportin1 AAA PF00004.24 CBZ27343.1 - 7.4e-30 103.8 0.0 3.2e-27 95.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ27343.1 - 7.7e-11 42.2 0.0 0.00033 20.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ27343.1 - 5.1e-09 36.3 15.4 7.2e-05 22.8 1.1 4.3 2 2 2 4 4 4 2 AAA ATPase domain NACHT PF05729.7 CBZ27343.1 - 2.2e-08 33.9 0.2 0.0062 16.2 0.2 3.4 2 2 1 3 3 3 2 NACHT domain RNA_helicase PF00910.17 CBZ27343.1 - 3.1e-05 24.1 0.0 0.022 14.8 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 CBZ27343.1 - 4e-05 23.5 0.0 0.022 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBZ27343.1 - 4.4e-05 23.2 0.1 0.0036 17.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ27343.1 - 5.3e-05 24.0 0.1 0.0089 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBZ27343.1 - 0.0001 21.7 0.1 0.15 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CBZ27343.1 - 0.00015 22.0 0.3 0.048 13.9 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 CBZ27343.1 - 0.00021 20.7 1.9 0.47 10.0 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CBZ27343.1 - 0.00091 18.9 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase TIP49 PF06068.8 CBZ27343.1 - 0.001 17.8 0.0 0.0038 15.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus AAA_19 PF13245.1 CBZ27343.1 - 0.0016 18.1 0.2 2.4 7.9 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 CBZ27343.1 - 0.0016 18.4 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CBZ27343.1 - 0.0019 18.6 0.0 0.45 11.0 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 CBZ27343.1 - 0.002 17.3 0.3 0.16 11.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NB-ARC PF00931.17 CBZ27343.1 - 0.0026 16.6 0.1 0.061 12.1 0.0 2.5 3 0 0 3 3 3 1 NB-ARC domain AAA_14 PF13173.1 CBZ27343.1 - 0.0032 17.3 0.0 0.32 10.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBZ27343.1 - 0.0034 16.8 1.4 0.03 13.7 0.1 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family Sigma54_activat PF00158.21 CBZ27343.1 - 0.0046 16.4 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 CBZ27343.1 - 0.0049 15.8 0.0 0.33 9.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 CBZ27343.1 - 0.008 15.7 0.1 0.28 10.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CBZ27343.1 - 0.01 15.3 0.1 2.8 7.4 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 CBZ27343.1 - 0.036 14.3 0.1 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 CBZ27343.1 - 0.055 13.1 0.1 2.8 7.6 0.2 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 CBZ27343.1 - 0.07 12.5 0.0 0.4 10.0 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CBZ27343.1 - 0.071 12.1 0.4 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.16 CBZ27343.1 - 0.074 12.1 0.1 0.39 9.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PRK PF00485.13 CBZ27343.1 - 0.15 11.6 0.1 2.4 7.6 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family UPF0079 PF02367.12 CBZ27343.1 - 0.21 11.2 0.2 2 8.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 CBZ27343.1 - 0.21 11.0 0.6 5.3 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 CBZ27343.1 - 0.22 11.8 0.1 23 5.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CBZ27343.1 - 0.25 10.9 0.0 8.5 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.6 CBZ27343.1 - 0.28 9.8 0.0 0.47 9.1 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain Rad17 PF03215.10 CBZ27343.1 - 0.29 9.7 0.4 0.95 8.0 0.1 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein HEAT PF02985.17 CBZ27344.1 - 3.3e-10 39.1 18.5 0.063 13.3 0.1 8.0 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.1 CBZ27344.1 - 1.8e-09 37.7 10.9 0.00092 19.4 0.0 4.9 4 2 2 6 6 6 5 HEAT repeats Adaptin_N PF01602.15 CBZ27344.1 - 0.00015 20.2 0.3 0.36 9.0 0.0 3.6 2 2 2 4 4 4 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 CBZ27344.1 - 0.0016 18.7 0.2 4.9 7.6 0.0 3.6 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 CBZ27344.1 - 0.032 14.0 1.1 13 5.5 0.0 3.5 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TFIIS_M PF07500.9 CBZ27345.1 - 0.00026 21.0 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain YqeY PF09424.5 CBZ27345.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Yqey-like protein Zn_Tnp_IS1595 PF12760.2 CBZ27345.1 - 0.26 11.1 6.2 2 8.2 4.8 2.1 2 1 0 2 2 2 0 Transposase zinc-ribbon domain TFIIS_C PF01096.13 CBZ27345.1 - 0.34 10.5 5.7 0.3 10.7 0.5 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) TFIIS_M PF07500.9 CBZ27346.1 - 4.7e-16 58.8 0.3 8.1e-16 58.1 0.2 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CBZ27346.1 - 9.8e-15 53.9 4.5 1.8e-14 53.0 3.1 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.3 CBZ27346.1 - 6.2e-05 22.2 0.6 0.00016 20.9 0.4 1.7 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain Elf1 PF05129.8 CBZ27346.1 - 0.11 12.2 1.4 0.2 11.3 1.0 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-DNL PF05180.7 CBZ27346.1 - 3.4 7.4 4.8 1.4 8.6 1.4 1.8 2 1 0 2 2 2 0 DNL zinc finger ubiquitin PF00240.18 CBZ27347.1 - 0.025 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Zfx_Zfy_act PF04704.8 CBZ27347.1 - 0.057 12.2 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Zfx / Zfy transcription activation region Pkinase PF00069.20 CBZ27348.1 - 2.4e-52 177.6 0.0 5.6e-52 176.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27348.1 - 3.9e-25 88.3 0.0 7e-20 71.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 CBZ27348.1 - 1.7e-15 56.8 0.2 4.8e-15 55.4 0.1 1.9 1 0 0 1 1 1 1 FHA domain APH PF01636.18 CBZ27348.1 - 0.0003 20.6 0.2 0.38 10.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family CAF1C_H4-bd PF12265.3 CBZ27349.1 - 6.4e-15 54.8 0.2 1.4e-14 53.7 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 CBZ27349.1 - 5.8e-10 38.6 11.1 0.00034 20.3 0.6 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CBZ27349.1 - 0.00068 18.5 0.0 0.00095 18.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region DEAD PF00270.24 CBZ27350.1 - 3.8e-33 114.3 2.1 4.8e-33 114.0 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ27350.1 - 3.8e-14 52.3 0.1 7.4e-08 32.1 0.1 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ27350.1 - 1.3e-05 25.0 0.0 0.00012 22.0 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CBZ27350.1 - 5.1e-05 22.2 0.6 8.1e-05 21.5 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain ATP-synt_D PF01813.12 CBZ27351.1 - 0.15 11.6 0.1 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 ATP synthase subunit D Metallophos PF00149.23 CBZ27352.1 - 2.7e-10 39.9 0.0 6.2e-10 38.7 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase WD40 PF00400.27 CBZ27353.1 - 3.7e-13 48.7 5.0 1.7e-07 30.8 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat tify PF06200.9 CBZ27353.1 - 0.01 15.0 2.5 1.6 8.0 0.2 2.6 2 0 0 2 2 2 0 tify domain NIF PF03031.13 CBZ27354.1 - 2.1e-32 111.9 0.4 2.9e-32 111.5 0.3 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.7 CBZ27354.1 - 0.067 12.1 0.2 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF705) zf-C3HC4 PF00097.20 CBZ27355.1 - 0.033 13.8 7.1 0.11 12.2 4.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CBZ27355.1 - 7.7 6.5 11.6 0.28 11.1 3.0 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain Fumerase PF05681.9 CBZ27357.1 - 4.6e-86 288.2 0.0 5.9e-86 287.9 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Fumerase_C PF05683.7 CBZ27357.1 - 1.7e-78 262.5 0.0 2.5e-78 261.9 0.0 1.3 1 0 0 1 1 1 1 Fumarase C-terminus Rsm22 PF09243.5 CBZ27358.1 - 5.1e-29 101.1 0.7 2.4e-16 59.6 0.1 3.1 3 0 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_18 PF12847.2 CBZ27358.1 - 0.013 16.0 0.2 3.3 8.3 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ27358.1 - 0.14 12.6 0.0 6.8 7.2 0.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain Phosphodiest PF01663.17 CBZ27359.1 - 2e-09 37.2 0.9 3.6e-09 36.4 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CBZ27359.1 - 0.05 12.9 0.2 0.083 12.2 0.2 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily PIRT PF15099.1 CBZ27359.1 - 0.43 9.7 6.6 2.9 7.1 0.1 2.8 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Nuc_sug_transp PF04142.10 CBZ27361.1 - 1.5e-50 171.5 7.2 1.5e-50 171.5 5.0 1.5 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 CBZ27361.1 - 0.00083 19.5 4.5 0.00083 19.5 3.1 3.1 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 CBZ27361.1 - 0.2 10.5 14.1 0.045 12.6 7.4 1.7 2 1 0 2 2 2 0 UAA transporter family TPT PF03151.11 CBZ27361.1 - 7.2 6.2 21.7 3.3 7.3 0.5 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 CBZ27362.1 - 1.3e-50 171.7 7.2 1.3e-50 171.7 5.0 1.4 2 0 0 2 2 2 1 Nucleotide-sugar transporter EmrE PF13536.1 CBZ27362.1 - 0.00053 20.1 3.8 0.00053 20.1 2.6 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 CBZ27362.1 - 0.0073 16.3 1.8 0.0073 16.3 1.2 3.5 3 1 1 4 4 4 1 EamA-like transporter family UAA PF08449.6 CBZ27362.1 - 0.0096 14.8 10.3 0.018 13.9 7.1 1.5 1 1 0 1 1 1 1 UAA transporter family Aminotran_1_2 PF00155.16 CBZ27363.1 - 2.9e-70 237.0 0.0 3.3e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1192 PF06698.6 CBZ27364.1 - 2.5 7.9 7.9 9.2 6.1 0.1 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) TPR_11 PF13414.1 CBZ27366.1 - 3.9e-07 29.6 0.1 1.4e-06 27.8 0.1 2.0 1 1 0 1 1 1 1 TPR repeat Peptidase_C12 PF01088.16 CBZ27368.1 - 2.9e-59 199.8 0.0 4.2e-59 199.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 RPAP2_Rtr1 PF04181.8 CBZ27369.1 - 0.00087 19.3 0.4 0.003 17.6 0.0 2.1 2 0 0 2 2 2 1 Rtr1/RPAP2 family DUF3184 PF11380.3 CBZ27370.1 - 2.8e-96 323.0 18.6 2.8e-54 184.2 4.6 4.9 3 1 0 4 4 4 4 Protein of unknown function (DUF3184) DUF3184 PF11380.3 CBZ27371.1 - 4.3e-95 319.1 18.2 1.1e-53 182.2 3.6 4.9 3 1 1 4 4 4 4 Protein of unknown function (DUF3184) ThiF PF00899.16 CBZ27372.1 - 7.7e-35 119.6 0.8 1.3e-34 118.9 0.6 1.3 1 0 0 1 1 1 1 ThiF family Response_reg PF00072.19 CBZ27372.1 - 3.5e-05 23.7 0.1 6.4e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Shikimate_DH PF01488.15 CBZ27372.1 - 0.016 15.3 0.5 0.033 14.2 0.4 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CBZ27372.1 - 0.023 15.1 0.2 0.088 13.2 0.0 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 CBZ27372.1 - 0.025 14.8 0.2 0.063 13.5 0.2 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding HHH_5 PF14520.1 CBZ27372.1 - 0.1 12.7 0.1 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain adh_short PF00106.20 CBZ27372.1 - 0.12 12.2 1.1 0.37 10.6 0.8 1.9 1 1 0 1 1 1 0 short chain dehydrogenase Saccharop_dh PF03435.13 CBZ27372.1 - 0.17 10.7 1.7 0.3 10.0 1.2 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NYD-SP28 PF14772.1 CBZ27372.1 - 4.3 7.4 7.9 8.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Sperm tail Kelch_4 PF13418.1 CBZ27374.1 - 1.5e-31 107.9 4.6 6.8e-09 35.3 0.0 7.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ27374.1 - 6.8e-23 80.1 0.4 2.3e-08 33.7 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 CBZ27374.1 - 1e-20 72.9 0.7 0.00011 22.2 0.0 7.0 5 1 2 7 7 7 4 Kelch motif Kelch_3 PF13415.1 CBZ27374.1 - 4.2e-14 52.2 22.6 4.9e-06 26.5 0.1 9.6 10 1 0 10 10 10 3 Galactose oxidase, central domain Kelch_2 PF07646.10 CBZ27374.1 - 5e-09 35.5 0.8 0.0013 18.3 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 CBZ27374.1 - 2.2e-07 30.2 1.6 7e-05 22.2 0.0 4.9 6 0 0 6 6 6 1 Kelch motif zf-CGNR PF11706.3 CBZ27374.1 - 1.7 8.2 11.5 0.11 12.0 0.1 3.7 3 0 0 3 3 3 0 CGNR zinc finger LRR_4 PF12799.2 CBZ27375.1 - 2.2e-63 209.0 62.5 4.9e-08 32.4 0.4 13.9 12 2 3 15 15 15 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ27375.1 - 8.4e-47 156.7 64.5 5.6e-09 35.6 0.9 10.0 8 2 1 9 9 9 7 Leucine rich repeat LRR_9 PF14580.1 CBZ27375.1 - 3.5e-22 78.7 18.2 6.1e-05 22.6 0.1 7.5 5 2 1 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.28 CBZ27375.1 - 4.9e-16 56.2 71.6 1.3 9.3 0.3 19.6 19 3 2 21 21 21 9 Leucine Rich Repeat LRR_7 PF13504.1 CBZ27375.1 - 6.8e-13 46.5 68.4 3.6 8.1 0.2 19.9 19 1 1 20 20 20 8 Leucine rich repeat LRR_6 PF13516.1 CBZ27375.1 - 1.4e-08 33.9 42.0 6.2 7.2 0.0 17.7 17 2 2 19 19 19 2 Leucine Rich repeat Spectrin PF00435.16 CBZ27377.1 - 0.0027 17.9 9.3 0.0027 17.9 6.5 5.4 4 2 2 6 6 6 1 Spectrin repeat DUF1664 PF07889.7 CBZ27377.1 - 1 9.1 12.5 0.03 14.1 1.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3595 PF12166.3 CBZ27377.1 - 1.7 7.3 6.8 0.17 10.6 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3595) ADIP PF11559.3 CBZ27377.1 - 3.6 7.4 41.9 0.3 10.9 11.5 3.9 4 0 0 4 4 4 0 Afadin- and alpha -actinin-Binding DnaJ PF00226.26 CBZ27378.1 - 4.7e-16 58.2 2.7 9.6e-16 57.2 1.9 1.6 1 0 0 1 1 1 1 DnaJ domain tRNA-synt_His PF13393.1 CBZ27378.1 - 0.026 13.6 1.1 0.033 13.2 0.1 1.6 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Metal_resist PF13801.1 CBZ27378.1 - 0.073 13.0 0.1 0.073 13.0 0.1 2.3 3 0 0 3 3 3 0 Heavy-metal resistance TRM13 PF05206.9 CBZ27380.1 - 1.5e-13 50.5 0.5 2.1e-06 27.1 0.2 2.2 2 0 0 2 2 2 2 Methyltransferase TRM13 Methyltransf_32 PF13679.1 CBZ27380.1 - 2.8e-07 30.3 0.1 1.7e-06 27.8 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 CBZ27380.1 - 0.044 12.9 0.2 0.077 12.1 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_23 PF13489.1 CBZ27380.1 - 0.048 13.3 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain TRM13 PF05206.9 CBZ27381.1 - 1.6e-19 70.1 0.0 2.4e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_32 PF13679.1 CBZ27381.1 - 1.5e-06 27.9 1.5 1.7e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 CBZ27381.1 - 0.048 12.8 0.2 0.09 11.9 0.1 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_23 PF13489.1 CBZ27381.1 - 0.066 12.9 0.0 0.19 11.4 0.0 1.7 1 1 1 2 2 2 0 Methyltransferase domain MAS20 PF02064.10 CBZ27382.1 - 0.0062 16.4 0.0 0.0079 16.1 0.0 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor WBP-1 PF11669.3 CBZ27382.1 - 0.0087 16.1 1.0 0.014 15.4 0.7 1.3 1 1 0 1 1 1 1 WW domain-binding protein 1 RSN1_TM PF13967.1 CBZ27382.1 - 0.065 12.7 0.0 0.084 12.4 0.0 1.1 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Protocadherin PF08374.6 CBZ27383.1 - 0.056 13.0 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Protocadherin Npa1 PF11707.3 CBZ27386.1 - 1.3e-06 27.6 0.0 3.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal MOR2-PAG1_N PF14222.1 CBZ27386.1 - 0.004 15.9 0.1 0.0074 15.0 0.1 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal SNF2_N PF00176.18 CBZ27387.1 - 3e-36 124.7 0.0 4.5e-36 124.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ27387.1 - 1.9e-09 37.2 0.0 2.8e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ27387.1 - 3.7e-07 29.7 0.0 7e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ27387.1 - 2.7e-05 24.0 0.0 0.00084 19.2 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 CBZ27387.1 - 0.013 15.2 0.3 0.15 11.8 0.0 2.6 2 0 0 2 2 2 0 Flavivirus DEAD domain UCH PF00443.24 CBZ27388.1 - 1.4e-47 162.1 0.0 2e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ27388.1 - 1.2e-11 44.5 0.0 3.1e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ATP-synt_C PF00137.16 CBZ27389.1 - 1e-16 60.5 13.5 1e-16 60.5 9.4 1.6 2 0 0 2 2 2 1 ATP synthase subunit C Kinesin PF00225.18 CBZ27390.1 - 1.8e-91 306.3 0.0 2.3e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_C97 PF05903.9 CBZ27391.1 - 3.2e-28 98.3 0.0 9.2e-28 96.9 0.0 1.7 2 0 0 2 2 2 1 PPPDE putative peptidase domain LRAT PF04970.8 CBZ27391.1 - 0.0086 16.0 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF2607 PF10795.4 CBZ27391.1 - 0.045 13.5 0.2 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2607) Pkinase PF00069.20 CBZ27393.1 - 9e-34 116.7 0.0 1.6e-33 115.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27393.1 - 1.2e-10 40.9 0.0 7.7e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sugar_tr PF00083.19 CBZ27394.1 - 1.8e-124 415.7 37.2 2e-124 415.6 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBZ27394.1 - 3.2e-29 101.7 78.4 1.2e-28 99.8 27.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CBZ27394.1 - 1.2e-06 27.2 33.0 7.7e-05 21.2 3.5 3.3 1 1 2 3 3 3 3 MFS/sugar transport protein DUF1019 PF06254.6 CBZ27396.1 - 0.1 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) DUF523 PF04463.7 CBZ27397.1 - 5.5e-15 55.3 0.0 1.2e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF523) zf-Tim10_DDP PF02953.10 CBZ27398.1 - 1.4e-05 24.3 0.7 1.7e-05 23.9 0.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger SRP54 PF00448.17 CBZ27399.1 - 2.7e-74 248.8 1.2 4.9e-74 248.0 0.8 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CBZ27399.1 - 3.2e-24 85.1 2.3 3.2e-24 85.1 1.6 4.9 3 1 0 4 4 2 1 Signal peptide binding domain SRP54_N PF02881.14 CBZ27399.1 - 6.5e-13 48.5 1.1 2e-12 46.9 0.8 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 CBZ27399.1 - 6.7e-09 35.4 0.3 2e-08 33.8 0.2 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CBZ27399.1 - 1e-06 28.7 0.1 2.9e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain CbiA PF01656.18 CBZ27399.1 - 1.5e-05 24.5 0.9 4.3e-05 22.9 0.1 2.1 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 CBZ27399.1 - 4.3e-05 23.6 0.3 0.001 19.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CBZ27399.1 - 7.7e-05 22.4 0.9 0.00082 19.1 0.1 2.7 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 CBZ27399.1 - 0.00035 19.7 0.1 0.00076 18.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_31 PF13614.1 CBZ27399.1 - 0.00045 20.1 0.0 1.5 8.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CBZ27399.1 - 0.0023 17.9 0.0 0.0049 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Methyltransf_24 PF13578.1 CBZ27399.1 - 0.0029 18.4 0.0 0.017 15.9 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain ArgK PF03308.11 CBZ27399.1 - 0.0031 16.3 0.0 0.015 14.0 0.0 2.1 1 1 0 1 1 1 1 ArgK protein SRPRB PF09439.5 CBZ27399.1 - 0.0049 16.1 0.4 2.8 7.1 0.1 2.5 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_17 PF13207.1 CBZ27399.1 - 0.006 17.4 0.0 0.014 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBZ27399.1 - 0.0086 15.6 0.3 0.0086 15.6 0.2 2.5 3 1 0 3 3 3 1 AAA domain APS_kinase PF01583.15 CBZ27399.1 - 0.0099 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP_bind_1 PF03029.12 CBZ27399.1 - 0.013 15.1 0.4 0.097 12.1 0.3 2.4 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 CBZ27399.1 - 0.021 14.2 0.0 0.069 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CBZ27399.1 - 0.12 12.2 1.2 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.10 CBZ27399.1 - 0.15 11.8 2.2 6.5 6.4 0.0 2.5 1 1 1 2 2 2 0 NTPase Response_reg PF00072.19 CBZ27399.1 - 0.22 11.5 2.2 0.27 11.2 0.0 2.4 3 0 0 3 3 2 0 Response regulator receiver domain CENP-F_leu_zip PF10473.4 CBZ27401.1 - 0.00078 19.3 4.0 0.00078 19.3 2.7 1.7 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 CBZ27401.1 - 0.0068 16.1 2.4 0.0068 16.1 1.7 1.6 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding PV-1 PF06637.6 CBZ27401.1 - 0.0075 14.8 2.8 0.011 14.3 1.9 1.2 1 0 0 1 1 1 1 PV-1 protein (PLVAP) DUF2984 PF11203.3 CBZ27401.1 - 0.079 13.0 2.5 1 9.4 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2984) Peptidase_S46 PF10459.4 CBZ27401.1 - 0.093 11.1 5.7 0.11 10.8 3.9 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF641 PF04859.7 CBZ27401.1 - 0.16 11.6 6.5 0.12 12.1 0.5 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 CBZ27401.1 - 0.81 9.2 5.8 1.6 8.2 4.0 1.5 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 CBZ27401.1 - 1.3 8.6 4.9 0.76 9.3 1.9 1.7 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CBZ27401.1 - 7.1 7.0 6.5 2.1 8.7 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) SNF2_N PF00176.18 CBZ27402.1 - 7.7e-61 205.4 0.0 1.3e-60 204.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ27402.1 - 1.9e-13 50.0 0.0 5.1e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ27402.1 - 1.5e-11 44.0 0.0 3.7e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ27402.1 - 0.00083 19.2 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Malic_M PF03949.10 CBZ27403.1 - 1.4e-75 254.1 0.3 1.8e-75 253.7 0.2 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CBZ27403.1 - 1.1e-66 223.9 0.0 3.4e-66 222.3 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Malic_M PF03949.10 CBZ27404.1 - 1.4e-74 250.8 0.1 2e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CBZ27404.1 - 2.3e-69 232.6 0.0 3.9e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain tRNA_edit PF04073.10 CBZ27404.1 - 0.054 13.3 0.1 0.099 12.4 0.1 1.4 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain Nop10p PF04135.7 CBZ27405.1 - 0.4 10.4 2.5 0.43 10.3 0.1 2.2 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family cIII PF08134.6 CBZ27407.1 - 0.087 12.4 0.1 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 cIII protein family PTS_2-RNA PF01885.11 CBZ27408.1 - 1.4e-51 174.4 0.1 2.1e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RNase_T PF00929.19 CBZ27408.1 - 1e-16 61.6 0.0 1.9e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Syja_N PF02383.13 CBZ27409.1 - 6.8e-69 232.0 0.0 9.6e-69 231.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain DUF547 PF04784.9 CBZ27409.1 - 0.038 13.8 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF547 Ax_dynein_light PF10211.4 CBZ27411.1 - 1.4e-78 263.1 4.9 1.6e-78 262.9 3.4 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Filament PF00038.16 CBZ27411.1 - 4e-05 23.2 9.2 0.00054 19.5 2.3 2.1 1 1 1 2 2 2 2 Intermediate filament protein ERM PF00769.14 CBZ27411.1 - 0.00031 20.3 9.4 0.00046 19.7 6.5 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family OmpH PF03938.9 CBZ27411.1 - 0.00043 20.2 3.1 0.0006 19.7 2.1 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) APG6 PF04111.7 CBZ27411.1 - 0.00051 19.2 5.4 0.00071 18.7 3.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 Syntaxin-6_N PF09177.6 CBZ27411.1 - 0.013 15.8 4.1 0.028 14.7 2.9 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal bZIP_1 PF00170.16 CBZ27411.1 - 0.018 14.9 3.0 0.018 14.9 2.0 2.1 2 0 0 2 2 2 0 bZIP transcription factor Spc24 PF08286.6 CBZ27411.1 - 0.041 13.5 4.4 0.069 12.8 3.1 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 HALZ PF02183.13 CBZ27411.1 - 0.053 13.2 3.8 0.43 10.3 0.9 3.0 3 0 0 3 3 3 0 Homeobox associated leucine zipper Fmp27_WPPW PF10359.4 CBZ27411.1 - 0.059 11.7 2.7 0.077 11.4 1.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Mei5 PF10376.4 CBZ27411.1 - 0.12 11.9 4.7 0.18 11.2 3.3 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF972 PF06156.8 CBZ27411.1 - 0.2 11.9 4.1 0.18 12.1 2.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF972) CENP-H PF05837.7 CBZ27411.1 - 0.23 11.6 4.9 0.41 10.8 3.4 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Mnd1 PF03962.10 CBZ27411.1 - 0.68 9.5 8.3 1.1 8.8 5.8 1.3 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 CBZ27411.1 - 2.8 7.5 9.8 0.4 10.1 2.9 2.3 2 1 1 3 3 3 0 Septum formation initiator Prefoldin PF02996.12 CBZ27411.1 - 2.9 7.5 7.6 1.5 8.4 0.6 2.5 2 1 1 3 3 2 0 Prefoldin subunit IncA PF04156.9 CBZ27411.1 - 3.4 7.2 15.2 0.86 9.1 7.9 1.7 1 1 1 2 2 2 0 IncA protein FlxA PF14282.1 CBZ27411.1 - 4.6 7.2 6.9 0.9 9.5 2.2 1.8 2 0 0 2 2 2 0 FlxA-like protein TIM PF00121.13 CBZ27412.1 - 3.9e-88 294.6 1.0 4.4e-88 294.4 0.7 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase EMP24_GP25L PF01105.19 CBZ27414.1 - 4.5e-14 52.5 0.0 5.5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ATG27 PF09451.5 CBZ27415.1 - 0.16 11.2 0.2 0.21 10.7 0.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 27 DNA_pol_A PF00476.15 CBZ27416.1 - 3.6e-36 124.6 0.0 4.4e-31 107.8 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family A P4Ha_N PF08336.6 CBZ27416.1 - 0.0073 16.1 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region MCM PF00493.18 CBZ27418.1 - 1.6e-118 395.3 0.0 2.8e-118 394.4 0.0 1.4 1 1 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBZ27418.1 - 5.7e-15 55.8 0.0 1.7e-14 54.3 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBZ27418.1 - 1.5e-07 30.8 0.0 3.6e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBZ27418.1 - 0.00032 20.2 0.0 0.00088 18.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ27418.1 - 0.00048 19.8 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PUA PF01472.15 CBZ27418.1 - 0.0037 16.9 1.7 0.85 9.3 0.1 2.6 2 0 0 2 2 2 2 PUA domain Sigma54_activat PF00158.21 CBZ27418.1 - 0.029 13.8 0.0 0.084 12.3 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain MTS PF05175.9 CBZ27419.1 - 0.0012 18.2 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CBZ27419.1 - 0.036 13.7 0.0 0.069 12.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ27419.1 - 0.047 14.0 0.1 0.27 11.6 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ27419.1 - 0.095 13.2 0.0 0.27 11.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ27419.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.13 CBZ27422.1 - 3e-09 36.6 2.0 1e-08 34.9 1.6 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain UCR_Fe-S_N PF10399.4 CBZ27422.1 - 1.2 8.3 5.1 5.5 6.2 0.7 2.4 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Phage_TAC PF06222.6 CBZ27424.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone RFC1 PF08519.7 CBZ27426.1 - 1.5e-47 161.1 0.0 4.5e-47 159.6 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 CBZ27426.1 - 1e-11 45.1 0.0 2.6e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBZ27426.1 - 1.9e-09 36.7 0.0 4.5e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CBZ27426.1 - 0.00027 21.7 0.0 0.0006 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ27426.1 - 0.00032 20.8 0.0 0.0011 19.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ27426.1 - 0.00082 19.2 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ27426.1 - 0.00095 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CBZ27426.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CBZ27426.1 - 0.0014 17.7 0.6 0.012 14.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 CBZ27426.1 - 0.0044 16.9 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ27426.1 - 0.016 15.5 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CBZ27426.1 - 0.019 14.8 0.3 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CBZ27426.1 - 0.023 14.7 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 CBZ27426.1 - 0.063 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 CBZ27426.1 - 0.089 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 NTPase Mnd1 PF03962.10 CBZ27428.1 - 9.5e-27 93.8 0.0 2.2e-26 92.6 0.0 1.6 1 1 0 1 1 1 1 Mnd1 family Kelch_4 PF13418.1 CBZ27429.1 - 8.7e-16 57.4 6.3 3.7e-07 29.7 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CBZ27429.1 - 9.5e-15 54.0 4.1 0.00014 21.8 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 CBZ27429.1 - 2.8e-12 45.9 2.1 8.6e-05 21.9 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CBZ27429.1 - 1.4e-09 37.6 1.3 0.00089 19.1 0.0 3.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 CBZ27429.1 - 4.2e-09 36.3 5.3 0.023 14.8 0.1 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain F-box-like PF12937.2 CBZ27429.1 - 1.4e-06 27.9 0.2 3.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CBZ27429.1 - 1.2e-05 24.8 0.1 3.1e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain Kelch_2 PF07646.10 CBZ27429.1 - 0.0014 18.3 0.3 0.63 9.9 0.0 3.3 3 0 0 3 3 3 1 Kelch motif LRR_4 PF12799.2 CBZ27430.1 - 1.4e-15 56.4 10.8 1.4e-07 30.9 0.5 3.3 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBZ27430.1 - 3e-09 36.7 6.2 6.1e-07 29.1 0.6 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.1 CBZ27430.1 - 4e-07 29.7 8.9 8e-06 25.5 0.7 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CBZ27430.1 - 0.00015 21.2 5.2 0.75 10.0 0.2 4.7 3 2 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ27430.1 - 0.00046 19.9 3.0 1.6 9.2 0.4 4.4 3 1 1 4 4 4 1 Leucine rich repeat LRR_6 PF13516.1 CBZ27430.1 - 0.0021 17.9 5.2 1.3 9.2 0.2 4.3 3 1 1 4 4 4 1 Leucine Rich repeat FNIP PF05725.7 CBZ27430.1 - 0.027 14.3 0.3 0.07 13.0 0.2 1.6 1 0 0 1 1 1 0 FNIP Repeat DUF3080 PF11279.3 CBZ27430.1 - 0.1 11.6 0.7 0.96 8.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) LRR_3 PF07725.7 CBZ27430.1 - 9.7 6.1 7.0 3.1 7.7 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat Rubredoxin PF00301.15 CBZ27431.1 - 0.45 10.4 0.0 0.45 10.4 0.0 3.2 4 0 0 4 4 4 0 Rubredoxin SNF2_N PF00176.18 CBZ27432.1 - 3.8e-36 124.4 0.0 1e-35 123.0 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ27432.1 - 1.9e-13 50.0 0.0 2.1e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ27432.1 - 0.033 14.0 0.0 0.88 9.3 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AKAP7_NLS PF10469.4 CBZ27433.1 - 8.4e-18 64.8 0.0 1.5e-17 63.9 0.0 1.4 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain zf-ribbon_3 PF13248.1 CBZ27433.1 - 0.2 10.9 0.8 0.38 10.0 0.6 1.5 1 0 0 1 1 1 0 zinc-ribbon domain TRAPPC10 PF12584.3 CBZ27434.1 - 0.0092 15.4 0.1 0.037 13.5 0.0 2.0 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 DUF169 PF02596.10 CBZ27434.1 - 0.11 11.8 0.2 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised ArCR, COG2043 DnaJ PF00226.26 CBZ27435.1 - 1.2e-15 56.9 0.1 1.3e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain Flavi_DEAD PF07652.9 CBZ27435.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF962 PF06127.6 CBZ27436.1 - 0.064 13.1 8.5 0.11 12.4 1.5 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF962) HA2 PF04408.18 CBZ27437.1 - 1.8e-16 59.9 0.0 6.4e-16 58.2 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBZ27437.1 - 1.1e-12 47.7 0.0 2.8e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBZ27437.1 - 4.5e-11 42.4 0.0 1.2e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ27437.1 - 8.6e-06 25.3 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ27437.1 - 0.00045 20.3 0.0 0.0015 18.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CBZ27437.1 - 0.017 15.4 0.2 0.18 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CBZ27437.1 - 0.017 14.8 0.3 0.017 14.8 0.2 2.2 2 0 0 2 2 2 0 Part of AAA domain cobW PF02492.14 CBZ27437.1 - 0.12 11.8 0.1 0.31 10.4 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CBZ27437.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter FH2 PF02181.18 CBZ27438.1 - 5.9e-51 173.4 0.0 7.6e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.4 CBZ27438.1 - 0.0067 16.1 0.0 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein EF-hand_6 PF13405.1 CBZ27439.1 - 0.12 12.2 0.0 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain IncA PF04156.9 CBZ27441.1 - 0.0043 16.6 5.8 0.0043 16.6 4.0 5.5 4 2 1 5 5 5 3 IncA protein TMF_TATA_bd PF12325.3 CBZ27441.1 - 0.01 15.5 3.6 0.01 15.5 2.5 6.9 5 2 2 7 7 7 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.6 CBZ27441.1 - 0.012 15.4 1.3 0.012 15.4 0.9 6.4 4 2 1 6 6 6 0 Autophagy protein 16 (ATG16) DUF869 PF05911.6 CBZ27441.1 - 6.2 4.9 44.6 0.044 12.0 14.2 3.8 3 1 0 4 4 4 0 Plant protein of unknown function (DUF869) RNA_pol PF00940.14 CBZ27443.1 - 3.5e-128 427.5 0.0 5.1e-128 427.0 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase Prominin PF05478.6 CBZ27444.1 - 0.21 9.0 3.1 0.36 8.3 2.1 1.3 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.1 CBZ27444.1 - 2.2 7.1 17.0 0.04 12.8 5.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Adaptin_binding PF10199.4 CBZ27445.1 - 0.00013 22.2 0.1 0.76 10.0 0.1 3.6 3 1 0 3 3 3 2 Alpha and gamma adaptin binding protein p34 SURF6 PF04935.7 CBZ27446.1 - 1.9e-13 50.2 12.0 3.2e-13 49.4 8.3 1.5 1 0 0 1 1 1 1 Surfeit locus protein 6 DUF29 PF01724.11 CBZ27446.1 - 3.7 7.3 6.0 5.2 6.9 3.4 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF29 Bax1-I PF01027.15 CBZ27447.1 - 6e-37 127.2 19.3 6e-37 127.2 13.3 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 YL1 PF05764.8 CBZ27448.1 - 8.4e-05 22.2 30.6 0.00036 20.2 21.2 1.9 1 1 0 1 1 1 1 YL1 nuclear protein HD_4 PF13328.1 CBZ27448.1 - 0.81 9.3 8.6 0.15 11.7 3.5 1.6 2 0 0 2 2 2 0 HD domain RNA_pol_3_Rpc31 PF11705.3 CBZ27448.1 - 7 6.5 21.5 1.2 8.9 9.3 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SUI1 PF01253.17 CBZ27449.1 - 3.1e-24 84.5 0.4 4.3e-24 84.1 0.3 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Acylphosphatase PF00708.13 CBZ27449.1 - 0.046 13.8 0.1 0.077 13.1 0.0 1.4 1 1 0 1 1 1 0 Acylphosphatase RIP PF00161.14 CBZ27449.1 - 0.067 12.3 0.2 0.076 12.1 0.1 1.1 1 0 0 1 1 1 0 Ribosome inactivating protein RRM_6 PF14259.1 CBZ27450.1 - 0.0038 17.1 0.0 0.008 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ27450.1 - 0.0069 15.9 0.0 0.018 14.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27450.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2520 PF10728.4 CBZ27450.1 - 0.075 12.4 1.2 0.22 11.0 0.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Spuma_A9PTase PF03539.9 CBZ27450.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) PHD PF00628.24 CBZ27451.1 - 1.4e-05 24.6 10.2 2.6e-05 23.8 7.0 1.5 1 0 0 1 1 1 1 PHD-finger Acetyltransf_7 PF13508.1 CBZ27451.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CBZ27451.1 - 0.052 13.5 1.3 0.35 10.9 0.2 2.6 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CBZ27451.1 - 0.16 11.7 0.6 1 9.2 0.4 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Amastin PF07344.6 CBZ27453.1 - 1.2e-35 122.4 10.6 1.5e-35 122.0 7.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_C7 PF01830.13 CBZ27453.1 - 0.0088 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C7 family Amastin PF07344.6 CBZ27454.1 - 4.2e-42 143.3 13.5 5.2e-42 143.0 9.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.6 CBZ27455.1 - 2.4e-41 140.9 17.7 2.9e-41 140.6 12.3 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.6 CBZ27456.1 - 1.2e-35 122.4 10.6 1.5e-35 122.0 7.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_C7 PF01830.13 CBZ27456.1 - 0.0088 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C7 family WASH-7_mid PF14744.1 CBZ27457.1 - 1.3e-139 464.9 0.1 2.1e-139 464.2 0.1 1.3 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.1 CBZ27457.1 - 8.8e-53 178.3 0.0 1.9e-52 177.2 0.0 1.6 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal WASH-7_N PF14745.1 CBZ27457.1 - 7.2e-44 149.9 0.0 3.9e-21 74.8 0.0 2.8 2 2 0 2 2 2 2 WASH complex subunit 7, N-terminal DnaJ PF00226.26 CBZ27458.1 - 7.6e-10 38.3 0.1 2.2e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain PAS PF00989.19 CBZ27458.1 - 0.076 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 PAS fold DUF4461 PF14688.1 CBZ27458.1 - 0.14 11.5 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) BLUF PF04940.7 CBZ27459.1 - 0.043 13.5 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 Sensors of blue-light using FAD Pro_isomerase PF00160.16 CBZ27460.1 - 2.5e-25 89.4 0.0 3.2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRAPP PF04051.11 CBZ27461.1 - 4e-06 26.4 0.0 4.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GTP_EFTU PF00009.22 CBZ27463.1 - 8.4e-24 84.0 0.8 2.5e-22 79.2 0.5 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ27463.1 - 1.5e-09 37.8 0.2 8e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CBZ27463.1 - 9.7e-06 25.1 0.1 0.00011 21.7 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CBZ27463.1 - 1.6e-05 25.3 0.0 5.4e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein IF-2 PF11987.3 CBZ27463.1 - 0.00016 21.5 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 Translation-initiation factor 2 Dynamin_N PF00350.18 CBZ27463.1 - 0.0033 17.2 0.1 0.041 13.7 0.0 2.5 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 CBZ27463.1 - 0.0086 15.3 0.0 0.019 14.2 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 CBZ27463.1 - 0.0094 15.1 0.0 0.04 13.1 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.14 CBZ27463.1 - 0.22 10.9 2.2 1.9 7.8 0.1 3.2 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain IQ PF00612.22 CBZ27464.1 - 3.7e-08 32.3 50.4 0.00048 19.5 1.0 7.9 6 1 1 7 7 7 4 IQ calmodulin-binding motif Hid1 PF12722.2 CBZ27465.1 - 9.7e-28 96.3 2.4 4.9e-14 51.0 0.1 3.4 3 1 0 3 3 3 3 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 CBZ27465.1 - 9.6e-23 80.1 0.0 7.3e-19 67.3 0.0 2.5 2 1 0 2 2 2 2 Dyggve-Melchior-Clausen syndrome protein ORC4_C PF14629.1 CBZ27465.1 - 0.34 10.2 1.9 13 5.0 0.2 2.4 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus Hist_deacetyl PF00850.14 CBZ27466.1 - 7.2e-69 232.4 0.6 9.4e-69 232.0 0.4 1.1 1 0 0 1 1 1 1 Histone deacetylase domain EF-hand_7 PF13499.1 CBZ27467.1 - 7.8e-20 70.7 5.6 1.4e-11 44.3 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ27467.1 - 4.9e-19 66.1 4.3 6.7e-05 21.9 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CBZ27467.1 - 5.3e-16 56.9 6.3 0.00073 19.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBZ27467.1 - 7.8e-16 56.6 5.0 9.1e-05 21.6 0.1 4.2 4 0 0 4 4 4 4 EF hand zf-C3HC4_3 PF13920.1 CBZ27467.1 - 2.9e-11 42.8 6.4 2.9e-11 42.8 4.5 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) EF-hand_8 PF13833.1 CBZ27467.1 - 1.6e-10 40.4 3.6 0.00012 21.6 0.1 4.0 3 1 1 4 4 4 2 EF-hand domain pair zf-C3HC4_2 PF13923.1 CBZ27467.1 - 4.1e-09 36.3 9.5 4.1e-09 36.3 6.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ27467.1 - 3.6e-08 33.0 6.4 3.6e-08 33.0 4.5 2.4 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBZ27467.1 - 5.2e-08 32.5 6.9 1.5e-07 31.0 4.8 1.9 1 0 0 1 1 1 1 Ring finger domain SPARC_Ca_bdg PF10591.4 CBZ27467.1 - 1.2e-07 31.6 0.1 2.8e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region zf-C3HC4 PF00097.20 CBZ27467.1 - 4.5e-07 29.4 7.0 4.5e-07 29.4 4.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBZ27467.1 - 3e-06 26.9 2.9 7.4e-06 25.6 2.0 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBZ27467.1 - 8.7e-05 22.1 5.8 0.00026 20.6 1.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBZ27467.1 - 9.7e-05 22.1 4.7 9.7e-05 22.1 3.3 2.6 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-C2HC5 PF06221.8 CBZ27467.1 - 0.0066 16.1 1.2 0.024 14.3 0.8 2.0 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type EF-hand_10 PF14788.1 CBZ27467.1 - 0.039 13.6 0.3 23 4.7 0.0 3.4 3 1 1 4 4 4 0 EF hand Prok-RING_4 PF14447.1 CBZ27467.1 - 0.053 13.0 3.6 0.16 11.5 2.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rtf2 PF04641.7 CBZ27467.1 - 0.061 12.5 0.4 0.085 12.0 0.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-Nse PF11789.3 CBZ27467.1 - 0.73 9.4 4.9 2.4 7.7 3.4 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cript PF10235.4 CBZ27467.1 - 2.2 8.7 9.3 0.32 11.3 0.7 2.8 2 1 1 3 3 3 0 Microtubule-associated protein CRIPT EF-hand_7 PF13499.1 CBZ27468.1 - 1.7e-20 72.9 6.3 3.5e-12 46.2 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ27468.1 - 1.4e-19 67.8 5.4 2.3e-05 23.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CBZ27468.1 - 8.9e-17 59.4 6.8 0.00028 20.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CBZ27468.1 - 1e-15 56.2 5.8 6.7e-05 22.0 0.1 4.2 4 0 0 4 4 4 4 EF hand zf-C3HC4_3 PF13920.1 CBZ27468.1 - 2.3e-11 43.1 6.4 2.3e-11 43.1 4.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) EF-hand_8 PF13833.1 CBZ27468.1 - 4.2e-11 42.2 4.8 5.3e-05 22.7 0.2 4.0 3 1 1 4 4 4 2 EF-hand domain pair zf-C3HC4_2 PF13923.1 CBZ27468.1 - 3.3e-09 36.6 9.5 3.3e-09 36.6 6.6 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ27468.1 - 2.8e-08 33.3 6.4 2.8e-08 33.3 4.5 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBZ27468.1 - 2.3e-07 30.3 6.5 2.3e-07 30.3 4.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ27468.1 - 2.4e-07 30.4 9.3 7.5e-07 28.8 6.5 1.9 1 1 0 1 1 1 1 Ring finger domain SPARC_Ca_bdg PF10591.4 CBZ27468.1 - 3.9e-07 30.1 1.9 1.1e-05 25.3 0.0 2.5 3 0 0 3 3 2 1 Secreted protein acidic and rich in cysteine Ca binding region zf-RING_6 PF14835.1 CBZ27468.1 - 2.1e-06 27.3 2.8 4.9e-06 26.2 1.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBZ27468.1 - 5.9e-05 22.6 5.8 0.00021 20.9 1.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBZ27468.1 - 8.4e-05 22.3 4.8 8.4e-05 22.3 3.4 2.6 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING EF-hand_10 PF14788.1 CBZ27468.1 - 0.014 15.0 0.5 18 5.0 0.0 3.4 3 1 1 4 4 4 0 EF hand zf-C2HC5 PF06221.8 CBZ27468.1 - 0.019 14.6 1.2 0.019 14.6 0.8 2.0 3 0 0 3 3 1 0 Putative zinc finger motif, C2HC5-type Prok-RING_4 PF14447.1 CBZ27468.1 - 0.049 13.1 3.6 0.13 11.8 2.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.3 CBZ27468.1 - 0.61 9.6 5.4 2.2 7.8 3.7 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DnaJ_CXXCXGXG PF00684.14 CBZ27468.1 - 2.1 8.4 9.1 0.84 9.7 4.3 1.8 2 1 0 2 2 1 0 DnaJ central domain Cript PF10235.4 CBZ27468.1 - 2.6 8.4 7.5 0.23 11.8 0.6 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT DUF641 PF04859.7 CBZ27469.1 - 0.34 10.6 18.5 0.29 10.9 3.6 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Cluap1 PF10234.4 CBZ27469.1 - 0.59 9.2 14.1 0.77 8.9 9.8 1.0 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4200 PF13863.1 CBZ27469.1 - 0.65 9.9 26.3 1.8 8.4 10.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.3 CBZ27469.1 - 1.1 8.9 20.7 0.14 11.9 8.6 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.14 CBZ27469.1 - 1.9 6.2 6.4 2.5 5.8 4.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF16 PF01519.11 CBZ27469.1 - 2.8 8.1 7.1 13 6.0 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF3584 PF12128.3 CBZ27469.1 - 4.7 4.4 19.2 6.3 3.9 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DNA_mis_repair PF01119.14 CBZ27471.1 - 2.4e-23 81.8 0.0 4.4e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CBZ27471.1 - 2.1e-09 37.1 0.0 4.3e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ27471.1 - 3.1e-08 33.3 0.0 6.9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kinesin PF00225.18 CBZ27472.1 - 6.2e-59 199.3 0.1 3.1e-40 137.9 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Effector_1 PF04518.7 CBZ27472.1 - 0.028 13.4 0.8 0.058 12.3 0.5 1.4 1 0 0 1 1 1 0 Effector from type III secretion system P4Ha_N PF08336.6 CBZ27472.1 - 0.17 11.6 2.3 0.41 10.4 1.6 1.5 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DivIC PF04977.10 CBZ27472.1 - 0.43 10.1 4.6 1.1 8.7 3.2 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF2450 PF10475.4 CBZ27472.1 - 4.4 6.1 0.6 7.2 5.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) DUF563 PF04577.9 CBZ27474.1 - 7.6e-13 48.8 0.0 1.3e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) HpcH_HpaI PF03328.9 CBZ27475.1 - 2.5e-19 69.0 0.0 1.1e-08 34.2 0.0 3.0 2 1 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 CBZ27475.1 - 3.8e-13 48.9 0.0 8.5e-07 28.1 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Pkinase PF00069.20 CBZ27476.1 - 4.9e-63 212.7 0.0 6.5e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27476.1 - 4e-41 140.8 0.0 5.9e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ27476.1 - 7.5e-05 21.8 0.0 0.00022 20.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-ribbon_3 PF13248.1 CBZ27476.1 - 0.00046 19.2 1.8 0.00088 18.3 1.3 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 CBZ27476.1 - 0.002 17.8 0.6 0.0041 16.8 0.4 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 CBZ27476.1 - 0.0041 16.5 2.3 0.0094 15.4 1.6 1.6 1 0 0 1 1 1 1 zinc-ribbon domain APH PF01636.18 CBZ27476.1 - 0.0059 16.3 0.0 0.32 10.7 0.1 2.9 1 1 2 3 3 3 1 Phosphotransferase enzyme family NOB1_Zn_bind PF08772.6 CBZ27476.1 - 0.0099 15.6 0.7 0.019 14.7 0.5 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF2931 PF11153.3 CBZ27476.1 - 0.063 12.6 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2931) Kinase-like PF14531.1 CBZ27476.1 - 0.071 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-NADH-PPase PF09297.6 CBZ27476.1 - 0.86 9.1 10.8 0.35 10.4 2.3 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ABC_tran PF00005.22 CBZ27477.1 - 4.9e-22 78.7 0.0 5.2e-08 33.2 0.0 4.6 4 0 0 4 4 4 4 ABC transporter ABC_membrane PF00664.18 CBZ27477.1 - 4.5e-14 52.5 12.3 2.9e-06 26.9 7.0 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region DUF258 PF03193.11 CBZ27477.1 - 0.18 10.9 0.4 2 7.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBZ27477.1 - 1 9.1 3.7 0.74 9.6 0.7 2.0 2 0 0 2 2 2 0 Dynamin family DUF2075 PF09848.4 CBZ27477.1 - 1.8 7.4 0.1 2.8 6.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) BatD PF13584.1 CBZ27477.1 - 4.4 5.7 0.0 6.6 5.2 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance WD40 PF00400.27 CBZ27479.1 - 0.00015 21.5 4.6 2.7 8.0 0.1 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat START PF01852.14 CBZ27480.1 - 0.00036 19.9 0.1 0.48 9.7 0.0 3.1 3 0 0 3 3 3 2 START domain DUF2921 PF11145.3 CBZ27480.1 - 0.00048 18.0 0.0 0.00068 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2921) Creb_binding PF09030.5 CBZ27480.1 - 0.72 10.0 6.8 0.09 12.9 1.0 2.3 2 0 0 2 2 2 0 Creb binding WD40 PF00400.27 CBZ27481.1 - 1.5e-15 56.4 3.0 7.5e-08 31.9 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat TRH PF05438.7 CBZ27481.1 - 0.056 12.8 0.2 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) TCTP PF00838.12 CBZ27482.1 - 1.7e-36 125.7 0.4 2e-36 125.4 0.3 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein Ribosomal_S20p PF01649.13 CBZ27482.1 - 0.022 15.1 0.6 0.045 14.1 0.4 1.5 1 0 0 1 1 1 0 Ribosomal protein S20 AlaDh_PNT_C PF01262.16 CBZ27482.1 - 0.089 12.3 0.7 0.28 10.7 0.2 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Trypan_glycop PF00913.14 CBZ27482.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) ERCC4 PF02732.10 CBZ27483.1 - 1.9e-10 40.6 0.0 4.8e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 ERCC4 domain SAP PF02037.22 CBZ27483.1 - 1.4e-05 24.4 0.1 3.7e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 SAP domain Helicase_C PF00271.26 CBZ27484.1 - 2.7e-15 55.9 0.0 1.8e-14 53.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ27484.1 - 3.5e-15 55.8 0.0 2e-14 53.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HRDC PF00570.18 CBZ27484.1 - 5.4e-05 22.8 0.0 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 HRDC domain Choline_kin_N PF04428.9 CBZ27484.1 - 0.082 12.3 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Choline kinase N terminus Clat_adaptor_s PF01217.15 CBZ27485.1 - 1.7e-44 150.9 0.8 2e-44 150.7 0.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain EF-hand_6 PF13405.1 CBZ27487.1 - 0.011 15.5 0.3 3.8 7.6 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 CBZ27487.1 - 0.049 12.9 0.7 16 5.1 0.0 3.1 3 0 0 3 3 3 0 EF hand RRM_1 PF00076.17 CBZ27488.1 - 3.6e-32 109.7 2.1 3.7e-22 77.7 0.0 3.3 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27488.1 - 1.8e-24 85.4 0.5 1.4e-14 53.8 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27488.1 - 4.2e-17 61.7 0.1 1.7e-10 40.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ27488.1 - 2.1e-05 24.1 0.1 0.018 14.8 0.0 2.7 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBZ27488.1 - 0.0029 17.3 0.0 0.0065 16.1 0.0 1.6 1 0 0 1 1 1 1 Limkain b1 RRM_3 PF08777.6 CBZ27488.1 - 0.24 11.2 0.1 1.5 8.6 0.0 2.2 3 0 0 3 3 3 0 RNA binding motif UBA PF00627.26 CBZ27489.1 - 3.3e-05 23.6 0.2 7.7e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CBZ27489.1 - 0.0046 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Rhomboid PF01694.17 CBZ27489.1 - 0.05 13.6 1.3 0.12 12.4 0.7 1.8 1 1 1 2 2 2 0 Rhomboid family Methyltrn_RNA_2 PF04013.7 CBZ27491.1 - 0.049 13.1 0.0 0.052 13.0 0.0 1.0 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase zf-rbx1 PF12678.2 CBZ27492.1 - 2e-22 79.0 8.7 2.8e-22 78.6 6.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CBZ27492.1 - 3.2e-12 46.1 10.3 5.1e-12 45.4 6.3 1.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CBZ27492.1 - 4.5e-08 32.7 15.2 8.4e-07 28.7 10.4 2.1 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ27492.1 - 2.6e-06 26.9 10.9 4e-05 23.1 7.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ27492.1 - 9.6e-06 25.5 5.3 9.6e-06 25.5 3.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ27492.1 - 1.1e-05 25.0 3.5 1.1e-05 25.0 2.4 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 CBZ27492.1 - 0.0028 17.6 4.5 0.0038 17.1 3.1 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING_5 PF14634.1 CBZ27492.1 - 0.07 12.8 13.4 0.77 9.5 9.3 2.1 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 CBZ27492.1 - 0.11 12.4 10.4 0.27 11.2 7.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.6 CBZ27492.1 - 0.36 10.6 5.5 1.3 8.8 3.8 1.8 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-HC5HC2H PF13771.1 CBZ27492.1 - 2 8.5 11.0 8.6 6.5 7.4 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain RINGv PF12906.2 CBZ27492.1 - 5.9 7.0 13.1 0.47 10.5 4.5 2.3 2 1 0 2 2 2 0 RING-variant domain zf-RING_UBOX PF13445.1 CBZ27492.1 - 7.8 6.3 10.5 0.073 12.8 1.8 1.9 2 1 0 2 2 2 0 RING-type zinc-finger GST_C_2 PF13410.1 CBZ27493.1 - 4.3e-06 26.5 0.0 1.3e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBZ27493.1 - 5.9e-05 23.4 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 CBZ27493.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin GST_N_3 PF13417.1 CBZ27493.1 - 0.065 13.4 0.1 0.69 10.1 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain FAD_binding_2 PF00890.19 CBZ27494.1 - 2.5e-117 392.2 2.9 1.8e-116 389.4 1.0 2.0 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.15 CBZ27494.1 - 6.3e-44 148.9 1.6 9.2e-44 148.4 1.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 CBZ27494.1 - 3.2e-05 23.0 0.2 0.02 13.7 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 CBZ27494.1 - 5.4e-05 22.3 0.1 0.033 13.2 0.1 2.7 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 CBZ27494.1 - 0.00036 20.4 0.0 0.01 15.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CBZ27494.1 - 0.017 13.5 0.1 0.028 12.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 CBZ27494.1 - 0.049 12.4 3.2 0.092 11.5 1.7 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 CBZ27494.1 - 0.21 10.4 2.6 1 8.2 0.4 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 CBZ27494.1 - 0.41 9.6 2.8 0.97 8.4 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_4 PF07993.7 CBZ27495.1 - 2.5e-64 216.5 0.0 3.6e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 CBZ27495.1 - 6.3e-09 35.6 0.0 4.7e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sterile PF03015.14 CBZ27495.1 - 1.1e-07 31.9 0.3 2.7e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CBZ27495.1 - 0.00072 18.5 0.0 0.2 10.5 0.0 3.0 3 0 0 3 3 3 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CBZ27495.1 - 0.012 14.3 0.3 0.84 8.2 0.1 2.7 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CBZ27495.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 CBZ27495.1 - 0.067 12.0 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TMF_TATA_bd PF12325.3 CBZ27496.1 - 0.011 15.4 13.5 0.011 15.4 9.3 4.2 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.6 CBZ27496.1 - 0.053 13.4 10.4 1.1 9.1 0.1 4.4 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF4515 PF14988.1 CBZ27496.1 - 0.72 9.4 49.0 0.17 11.5 18.4 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4515) DUF2935 PF11155.3 CBZ27496.1 - 4.8 7.2 17.5 9.2 6.3 0.2 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF2935) SpoU_methylase PF00588.14 CBZ27497.1 - 5.1e-14 52.3 0.0 1.2e-11 44.6 0.0 2.6 2 1 0 2 2 2 1 SpoU rRNA Methylase family BRF1 PF07741.8 CBZ27498.1 - 1.4 9.2 8.9 21 5.4 4.9 2.7 1 1 1 2 2 2 0 Brf1-like TBP-binding domain Ssl1 PF04056.9 CBZ27499.1 - 2.7e-18 66.2 0.2 4.8e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 Ssl1-like SET PF00856.23 CBZ27500.1 - 7.2e-10 39.3 0.0 3.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 SET domain TPR_1 PF00515.23 CBZ27500.1 - 0.00025 20.5 4.4 0.00043 19.7 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ27500.1 - 0.0094 15.7 4.0 0.015 15.1 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ27500.1 - 0.025 14.2 2.0 0.048 13.3 0.1 2.5 3 0 0 3 3 3 0 TPR repeat DUF2116 PF09889.4 CBZ27500.1 - 4.1 7.2 7.0 13 5.7 4.9 1.8 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) UQ_con PF00179.21 CBZ27502.1 - 8.7e-18 64.1 0.0 1.4e-17 63.4 0.0 1.3 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ27502.1 - 0.0081 15.9 0.0 0.025 14.3 0.0 1.7 1 1 0 2 2 2 1 Prokaryotic E2 family B WD40 PF00400.27 CBZ27503.1 - 1.4e-30 104.0 15.2 3.5e-08 33.0 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CBZ27503.1 - 4.4e-07 29.7 0.0 0.11 12.2 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CBZ27503.1 - 0.02 13.9 0.2 1.1 8.3 0.0 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 CBZ27503.1 - 0.09 10.5 0.9 1.4 6.5 0.0 2.5 2 1 0 2 2 2 0 IKI3 family Pkinase PF00069.20 CBZ27504.1 - 1.5e-48 165.2 0.0 2.2e-48 164.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27504.1 - 3.6e-25 88.5 0.0 9.2e-25 87.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ27504.1 - 2.3e-06 26.7 0.0 1.5e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like LRR_1 PF00560.28 CBZ27504.1 - 3e-06 26.5 1.2 0.33 11.1 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_8 PF13855.1 CBZ27504.1 - 7.2e-06 25.6 0.6 0.0005 19.7 0.1 3.0 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 CBZ27504.1 - 1.1e-05 24.8 1.3 0.021 14.4 0.0 3.7 3 1 0 4 4 4 1 Leucine Rich repeats (2 copies) C1_3 PF07649.7 CBZ27504.1 - 0.00025 20.9 9.7 0.00025 20.9 6.7 2.6 2 0 0 2 2 2 1 C1-like domain zf-B_box PF00643.19 CBZ27504.1 - 0.00029 20.6 20.2 0.0028 17.4 3.0 2.7 2 0 0 2 2 2 2 B-box zinc finger LRR_7 PF13504.1 CBZ27504.1 - 0.0063 16.5 3.3 1.8 9.1 0.0 4.1 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 CBZ27504.1 - 0.11 12.6 0.0 27 5.2 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat DisA-linker PF10635.4 CBZ27504.1 - 0.18 11.2 0.2 0.91 9.0 0.1 2.1 1 1 1 2 2 2 0 DisA bacterial checkpoint controller linker region DUF3751 PF12571.3 CBZ27504.1 - 0.21 11.3 0.0 0.54 10.0 0.0 1.6 1 0 0 1 1 1 0 Phage tail-collar fibre protein ZZ PF00569.12 CBZ27504.1 - 0.83 9.2 22.5 2.4 7.7 4.0 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-UBR PF02207.15 CBZ27504.1 - 6 6.6 16.6 0.079 12.6 1.8 3.2 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) GCV_T PF01571.16 CBZ27505.1 - 5.6e-17 61.8 0.0 7.9e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CBZ27505.1 - 1.2e-10 41.2 0.1 2.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SET PF00856.23 CBZ27506.1 - 1.7e-10 41.4 0.0 1.9e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 SET domain DUF568 PF04526.8 CBZ27507.1 - 0.044 14.0 0.0 0.11 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF568) Inhibitor_I42 PF09394.5 CBZ27508.1 - 7.7e-24 83.8 0.1 9e-24 83.6 0.0 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Inhibitor_I71 PF12628.2 CBZ27508.1 - 0.00062 19.4 0.2 0.67 9.5 0.0 2.0 1 1 1 2 2 2 2 Falstatin, cysteine peptidase inhibitor AMP-binding PF00501.23 CBZ27509.1 - 2.1e-19 69.2 3.8 4e-10 38.6 0.4 3.9 3 1 0 3 3 3 3 AMP-binding enzyme RRM_1 PF00076.17 CBZ27510.1 - 5.5e-16 57.9 0.1 1.1e-15 56.9 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27510.1 - 3.5e-13 49.3 0.0 5.9e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27510.1 - 3.3e-07 30.0 0.1 5.1e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 CBZ27510.1 - 3.6 5.7 38.4 4.6 5.3 26.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 adh_short PF00106.20 CBZ27512.1 - 1.1e-16 61.1 0.4 1.1e-16 61.1 0.3 2.4 4 0 0 4 4 4 1 short chain dehydrogenase KR PF08659.5 CBZ27512.1 - 2.5e-09 37.0 0.2 6e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBZ27512.1 - 0.006 16.0 0.1 0.0091 15.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 CBZ27512.1 - 0.014 15.6 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding dCMP_cyt_deam_1 PF00383.17 CBZ27512.1 - 0.018 14.6 0.5 0.15 11.6 0.3 2.3 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region NAD_binding_10 PF13460.1 CBZ27512.1 - 0.026 14.5 0.4 0.082 12.9 0.3 1.8 1 1 0 1 1 1 0 NADH(P)-binding ApbA PF02558.11 CBZ27512.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Eno-Rase_NADH_b PF12242.3 CBZ27512.1 - 7.1 6.4 7.6 0.38 10.5 0.1 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 CBZ27513.1 - 6.2e-16 58.7 2.1 1.4e-15 57.6 0.1 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CBZ27513.1 - 9.2e-08 31.9 0.2 3e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CBZ27513.1 - 0.00052 19.5 0.0 0.0011 18.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 CBZ27513.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase WVELL PF14043.1 CBZ27514.1 - 0.0041 16.7 0.4 0.0086 15.6 0.3 1.6 1 0 0 1 1 1 1 WVELL protein Amidase PF01425.16 CBZ27514.1 - 0.11 11.3 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Amidase Abhydrolase_2 PF02230.11 CBZ27515.1 - 1.8e-38 132.1 0.0 2.3e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CBZ27515.1 - 1.3e-10 41.2 0.1 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ27515.1 - 4.6e-06 26.6 0.6 0.011 15.6 0.2 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 CBZ27515.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 CBZ27515.1 - 0.054 12.7 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase_phd PF10503.4 CBZ27515.1 - 0.12 11.6 0.5 0.33 10.1 0.3 1.6 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_4 PF08386.5 CBZ27515.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF3770 PF12603.3 CBZ27517.1 - 0.1 11.6 0.3 0.18 10.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) SPRY PF00622.23 CBZ27518.1 - 0.0056 16.7 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 SPRY domain Cyclin PF08613.6 CBZ27519.1 - 3.9e-17 63.0 0.1 6.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBZ27519.1 - 7.5e-08 31.9 0.1 1.5e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CBZ27520.1 - 2.2e-19 70.3 0.0 3.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBZ27520.1 - 1.9e-06 27.4 0.1 3e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain WD40 PF00400.27 CBZ27521.1 - 2.2e-38 128.7 24.8 5e-09 35.6 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PFU PF09070.6 CBZ27521.1 - 1.9e-32 111.6 0.2 2.9e-32 111.0 0.1 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PPTA PF01239.17 CBZ27522.1 - 5.7e-05 22.2 10.4 0.049 12.9 0.1 3.7 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat DnaJ PF00226.26 CBZ27523.1 - 0.0021 17.7 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain HAP1_N PF04849.8 CBZ27524.1 - 0.11 11.3 20.1 0.027 13.4 8.0 2.4 2 0 0 2 2 2 0 HAP1 N-terminal conserved region ADIP PF11559.3 CBZ27524.1 - 1.2 8.9 26.5 1.1 9.1 4.8 3.3 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 CBZ27524.1 - 9.4 6.6 18.8 3 8.2 2.4 3.6 3 2 1 4 4 4 0 Protein of unknown function (DUF972) Ins134_P3_kin PF05770.6 CBZ27525.1 - 8.4e-06 25.0 0.5 0.013 14.5 0.0 3.9 4 0 0 4 4 4 2 Inositol 1, 3, 4-trisphosphate 5/6-kinase Seryl_tRNA_N PF02403.17 CBZ27528.1 - 0.61 10.1 23.4 0.037 14.0 0.8 3.7 2 2 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.1 CBZ27528.1 - 1.1 7.6 22.3 0.73 8.2 1.8 2.1 2 0 0 2 2 2 0 AAA domain STOP PF05217.7 CBZ27530.1 - 1.2e-08 34.9 16.3 8.8e-07 28.8 11.3 3.6 1 1 0 1 1 1 1 STOP protein TruB_C PF09142.6 CBZ27530.1 - 0.097 12.3 0.0 0.34 10.5 0.0 1.9 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal PCIF1_WW PF12237.3 CBZ27532.1 - 6.6e-08 32.0 0.0 1.9e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain PI3_PI4_kinase PF00454.22 CBZ27533.1 - 9.8e-43 146.2 0.0 1.4e-27 96.6 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CBZ27533.1 - 1.4e-22 79.7 0.0 2.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 CBZ27533.1 - 0.00011 21.9 0.0 0.00024 20.8 0.0 1.6 1 1 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4478 PF14793.1 CBZ27533.1 - 0.2 11.2 0.0 0.55 9.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) DUF4135 PF13575.1 CBZ27533.1 - 0.21 10.5 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TFCD_C PF12612.3 CBZ27534.1 - 2.1e-21 76.2 0.0 7.9e-21 74.3 0.0 2.0 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 CBZ27534.1 - 2.1e-08 34.3 17.8 0.036 14.3 0.1 7.5 7 0 0 7 7 7 4 HEAT repeats HEAT PF02985.17 CBZ27534.1 - 2e-06 27.3 31.6 0.32 11.1 0.0 11.3 11 1 1 12 12 12 4 HEAT repeat Cnd1 PF12717.2 CBZ27534.1 - 0.0091 15.8 2.1 5 6.9 0.0 4.7 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CBZ27534.1 - 1.5 9.3 42.5 0.31 11.5 1.3 10.2 9 1 1 10 10 10 0 HEAT-like repeat adh_short PF00106.20 CBZ27535.1 - 2.3e-25 89.4 4.9 3e-25 89.0 3.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBZ27535.1 - 1.1e-14 54.7 0.1 5.5e-14 52.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBZ27535.1 - 3.1e-11 43.2 3.7 6.5e-11 42.2 2.6 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CBZ27535.1 - 4.4e-06 26.2 0.3 6.9e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBZ27535.1 - 0.00057 19.9 0.7 0.00098 19.1 0.5 1.3 1 0 0 1 1 1 1 NADH(P)-binding DAO PF01266.19 CBZ27535.1 - 0.0019 17.2 0.1 0.0024 16.8 0.1 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase THF_DHG_CYH_C PF02882.14 CBZ27535.1 - 0.05 12.6 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 CBZ27535.1 - 0.062 12.4 0.4 0.13 11.4 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CBZ27535.1 - 0.071 12.7 0.4 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 CBZ27535.1 - 0.078 12.7 0.4 0.19 11.5 0.3 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_4 PF07993.7 CBZ27535.1 - 0.13 11.1 0.9 0.57 9.0 0.5 1.9 1 1 0 1 1 1 0 Male sterility protein BolA PF01722.13 CBZ27536.1 - 1.3e-16 60.2 0.0 1.7e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein KOW PF00467.24 CBZ27538.1 - 4.2e-07 29.4 0.9 1.1e-06 28.0 0.6 1.9 1 1 0 1 1 1 1 KOW motif Transketolase_N PF00456.16 CBZ27539.1 - 4.5e-136 453.0 0.0 5.9e-136 452.6 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CBZ27539.1 - 1.1e-42 145.4 0.0 1.8e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBZ27539.1 - 1.2e-10 41.4 0.1 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CBZ27539.1 - 0.00017 20.6 0.1 0.0022 16.9 0.0 2.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 CBZ27539.1 - 0.0007 19.1 0.6 0.0032 17.0 0.1 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 CBZ27539.1 - 0.0014 17.4 0.1 0.0023 16.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Terpene_synth PF01397.16 CBZ27539.1 - 0.16 11.3 0.0 0.45 9.8 0.0 1.6 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain Ribosomal_S8e PF01201.17 CBZ27540.1 - 2e-44 150.9 2.6 2.3e-44 150.7 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_S8e PF01201.17 CBZ27541.1 - 2e-44 150.9 2.6 2.3e-44 150.7 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Kelch_3 PF13415.1 CBZ27542.1 - 1.9e-48 161.6 8.8 2e-12 46.8 0.0 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 CBZ27542.1 - 4.5e-41 138.3 19.6 9.4e-08 31.7 0.0 7.0 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ27542.1 - 9.8e-31 105.2 15.4 2.7e-06 27.1 0.5 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 CBZ27542.1 - 1.3e-30 104.6 21.0 1.2e-06 27.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 CBZ27542.1 - 2.5e-30 103.3 12.1 6e-08 32.5 0.0 6.2 4 1 2 6 6 6 4 Kelch motif Kelch_2 PF07646.10 CBZ27542.1 - 7.4e-26 88.8 16.7 1.5e-06 27.6 0.3 6.6 6 1 0 6 6 6 6 Kelch motif HMG_CoA_synt_N PF01154.12 CBZ27544.1 - 4.8e-12 45.7 0.1 1.2e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 CBZ27544.1 - 1.2e-06 28.2 0.2 0.00061 19.3 0.0 2.6 3 0 0 3 3 3 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.5 CBZ27544.1 - 2.6e-05 23.8 0.2 0.0001 21.8 0.1 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.21 CBZ27546.1 - 3.9e-44 149.4 0.1 4.3e-44 149.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBZ27546.1 - 0.0002 21.2 0.1 0.00026 20.8 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 CBZ27546.1 - 0.00092 18.8 0.3 0.0015 18.2 0.2 1.4 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 CBZ27546.1 - 0.015 15.0 0.1 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UQ_con PF00179.21 CBZ27547.1 - 1.7e-07 30.7 0.1 3.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBZ27547.1 - 0.0028 17.5 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain GDPD PF03009.12 CBZ27549.1 - 1e-21 77.6 0.0 1.4e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF2450 PF10475.4 CBZ27550.1 - 1.3e-15 57.1 0.7 1.3e-15 57.1 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 CBZ27550.1 - 7.9e-07 29.0 0.6 1.5e-06 28.1 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.9 CBZ27550.1 - 0.0079 15.8 0.7 0.019 14.6 0.5 1.5 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF641 PF04859.7 CBZ27551.1 - 0.0027 17.4 4.5 0.0027 17.4 3.1 15.7 4 3 8 16 16 16 3 Plant protein of unknown function (DUF641) Reo_sigmaC PF04582.7 CBZ27551.1 - 0.0028 16.8 1.7 0.0028 16.8 1.2 9.5 2 2 5 10 10 10 7 Reovirus sigma C capsid protein FlxA PF14282.1 CBZ27551.1 - 0.0053 16.6 4.8 0.0053 16.6 3.3 14.8 6 3 8 15 15 15 2 FlxA-like protein PPR_3 PF13812.1 CBZ27553.1 - 1.3e-07 31.3 2.2 0.00012 22.0 0.0 4.2 4 1 0 4 4 4 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 CBZ27553.1 - 1.4e-07 31.3 0.0 0.0047 16.8 0.0 3.4 2 1 1 3 3 3 3 PPR repeat family PPR PF01535.15 CBZ27553.1 - 0.00064 19.5 0.1 2 8.5 0.0 3.8 4 0 0 4 4 4 1 PPR repeat Ribosomal_L11_N PF03946.9 CBZ27554.1 - 7.6e-15 54.1 0.2 1.3e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBZ27554.1 - 2.4e-11 43.6 0.5 4.5e-11 42.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain AAA_5 PF07728.9 CBZ27555.1 - 0.057 13.1 0.0 0.19 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ27555.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 CBZ27555.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Torsin DUF1516 PF07457.6 CBZ27556.1 - 0.55 10.3 4.0 0.38 10.8 0.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1516) DUF3671 PF12420.3 CBZ27556.1 - 0.83 9.6 3.8 4.1 7.4 2.6 1.9 1 1 0 1 1 1 0 Protein of unknown function 2TM PF13239.1 CBZ27556.1 - 7.1 6.7 8.0 2.2 8.4 2.0 2.1 2 0 0 2 2 2 0 2TM domain Wzz PF02706.10 CBZ27556.1 - 8.4 6.1 6.5 1.2 8.9 0.6 2.0 1 1 1 2 2 2 0 Chain length determinant protein Cob_adeno_trans PF01923.13 CBZ27557.1 - 9.9e-46 155.4 0.5 1.6e-45 154.8 0.3 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase FA_desaturase PF00487.19 CBZ27558.1 - 6e-14 52.1 22.6 9e-14 51.5 14.1 1.9 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.23 CBZ27558.1 - 1.9e-09 37.2 0.1 1.1e-06 28.3 0.1 3.2 2 1 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.27 CBZ27559.1 - 9.9e-79 256.6 26.3 6.1e-11 41.7 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 CBZ27559.1 - 1.6e-16 60.0 0.0 2.6e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 CBZ27559.1 - 1.6e-07 31.2 0.1 0.018 14.7 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CBZ27559.1 - 0.00021 20.8 2.3 2.9 7.6 0.1 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 CBZ27559.1 - 0.00054 19.1 0.6 0.47 9.5 0.0 3.7 3 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal zf-DHHC PF01529.15 CBZ27560.1 - 1.4e-14 53.8 9.0 1.4e-14 53.8 6.2 2.4 2 2 0 2 2 2 1 DHHC palmitoyltransferase DUF1227 PF06777.6 CBZ27561.1 - 1e-45 155.0 0.2 2.1e-45 153.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 CBZ27561.1 - 4.5e-40 137.3 0.0 9.7e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBZ27561.1 - 1.1e-37 129.1 0.0 2.2e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 CBZ27561.1 - 0.00024 20.6 0.7 0.052 13.0 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CBZ27561.1 - 0.0035 17.2 0.7 0.03 14.1 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Glyco_transf_21 PF13506.1 CBZ27561.1 - 0.017 14.4 0.1 0.39 9.9 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 21 Flavi_DEAD PF07652.9 CBZ27561.1 - 0.024 14.3 0.4 0.98 9.1 0.0 2.5 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_19 PF13245.1 CBZ27561.1 - 0.065 12.9 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain Cullin PF00888.17 CBZ27562.1 - 2.7e-69 234.2 0.0 3.6e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBZ27562.1 - 3e-26 91.0 0.2 9.8e-26 89.3 0.1 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain Vac_Fusion PF02346.11 CBZ27563.1 - 0.057 12.8 0.2 2.7 7.4 0.1 2.5 2 1 0 2 2 2 0 Chordopoxvirus fusion protein IncA PF04156.9 CBZ27564.1 - 0.0032 17.0 4.9 0.0032 17.0 3.4 2.1 1 1 0 2 2 2 1 IncA protein Pox_G5 PF04599.7 CBZ27564.1 - 0.035 12.7 0.3 0.04 12.6 0.2 1.1 1 0 0 1 1 1 0 Poxvirus G5 protein DUF4201 PF13870.1 CBZ27564.1 - 0.083 12.3 14.1 0.49 9.8 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) NurA PF09376.5 CBZ27564.1 - 0.1 12.0 0.6 0.11 11.9 0.4 1.1 1 0 0 1 1 1 0 NurA domain DUF2051 PF09738.4 CBZ27564.1 - 0.12 11.6 13.1 0.68 9.1 3.4 2.0 1 1 1 2 2 2 0 Double stranded RNA binding protein (DUF2051) FlgN PF05130.7 CBZ27564.1 - 0.18 12.0 14.3 0.18 12.0 7.8 2.0 1 1 1 2 2 2 0 FlgN protein DASH_Dad2 PF08654.5 CBZ27564.1 - 0.42 10.6 0.1 0.42 10.6 0.1 3.4 3 1 0 3 3 3 0 DASH complex subunit Dad2 Tup_N PF08581.5 CBZ27564.1 - 0.69 10.1 6.4 0.27 11.4 0.2 2.6 1 1 1 3 3 3 0 Tup N-terminal DivIC PF04977.10 CBZ27564.1 - 1.2 8.6 19.1 1.3 8.5 0.5 3.9 2 2 2 4 4 4 0 Septum formation initiator Snapin_Pallidin PF14712.1 CBZ27564.1 - 1.5 9.1 13.2 17 5.7 0.3 3.7 1 1 2 3 3 3 0 Snapin/Pallidin FlxA PF14282.1 CBZ27564.1 - 2.1 8.3 7.6 1.5 8.8 0.6 2.2 2 0 0 2 2 2 0 FlxA-like protein ADIP PF11559.3 CBZ27564.1 - 2.5 8.0 12.2 5.6 6.8 5.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.1 CBZ27564.1 - 2.5 6.9 8.2 4.2 6.2 5.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.11 CBZ27564.1 - 3.2 8.0 6.1 5.2 7.3 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 AAA_23 PF13476.1 CBZ27564.1 - 3.6 7.8 7.3 4.5 7.5 5.1 1.2 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 CBZ27564.1 - 4.5 6.8 12.1 22 4.6 8.4 1.9 1 1 0 1 1 1 0 Mnd1 family Prefoldin_2 PF01920.15 CBZ27564.1 - 6 6.6 13.2 11 5.8 5.3 3.0 1 1 1 2 2 2 0 Prefoldin subunit Pox_A_type_inc PF04508.7 CBZ27564.1 - 7.9 6.5 10.0 0.28 11.0 0.4 3.5 4 1 0 4 4 4 0 Viral A-type inclusion protein repeat Pkinase PF00069.20 CBZ27565.1 - 6.5e-58 195.9 0.0 7.6e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27565.1 - 1.7e-39 135.4 0.0 2.1e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ27565.1 - 9e-05 21.5 0.0 0.0003 19.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like GAGA_bind PF06217.7 CBZ27566.1 - 8 6.3 14.3 18 5.1 9.8 1.6 1 1 1 2 2 2 0 GAGA binding protein-like family SpoU_methylase PF00588.14 CBZ27567.1 - 2.1e-14 53.6 0.0 7.5e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family Glycos_transf_2 PF00535.21 CBZ27568.1 - 1.3e-07 31.4 0.0 3e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 CBZ27568.1 - 0.0035 16.4 0.1 0.91 8.5 0.1 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Acetyltransf_1 PF00583.19 CBZ27569.1 - 1.9e-08 34.2 0.0 3.5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CBZ27569.1 - 4e-07 29.6 0.1 6.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CBZ27569.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CBZ27569.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2431 PF10354.4 CBZ27570.1 - 3.6e-24 85.5 0.0 1.5e-18 67.3 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF2431) zf-C2H2_jaz PF12171.3 CBZ27570.1 - 4.7e-05 23.3 4.9 0.032 14.3 0.1 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CBZ27570.1 - 0.006 16.8 20.5 0.3 11.5 0.7 4.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBZ27570.1 - 0.0064 16.7 19.4 1.1 9.7 0.1 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 CBZ27570.1 - 0.078 13.2 0.1 0.078 13.2 0.1 3.2 3 1 0 3 3 3 0 Zinc-finger of C2H2 type Adeno_100 PF02438.11 CBZ27570.1 - 0.08 11.1 0.2 0.12 10.5 0.1 1.2 1 0 0 1 1 1 0 Late 100kD protein zf-C2H2_6 PF13912.1 CBZ27570.1 - 0.11 12.4 0.1 0.11 12.4 0.1 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger DUF972 PF06156.8 CBZ27571.1 - 0.1 12.9 0.2 0.1 12.9 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF972) HALZ PF02183.13 CBZ27571.1 - 0.1 12.3 0.1 0.1 12.3 0.1 3.5 5 0 0 5 5 5 0 Homeobox associated leucine zipper CEP44 PF15007.1 CBZ27572.1 - 0.00014 21.6 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Got1 PF04178.7 CBZ27573.1 - 3.9e-26 91.4 13.6 5.1e-26 91.1 9.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AzlD PF05437.7 CBZ27573.1 - 0.017 15.0 6.6 0.034 14.0 4.6 1.5 1 1 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) DUF3270 PF11674.3 CBZ27573.1 - 8.4 6.4 7.7 0.95 9.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) RRM_1 PF00076.17 CBZ27575.1 - 2.7e-65 215.9 0.4 6.6e-19 67.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27575.1 - 2.5e-48 161.9 0.3 5.9e-17 61.4 0.0 4.7 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27575.1 - 1.1e-32 111.6 0.6 1.4e-10 40.8 0.0 4.6 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CBZ27575.1 - 1.9e-18 65.8 0.2 4.1e-18 64.8 0.1 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CBZ27575.1 - 0.00066 19.5 1.3 1.9 8.3 0.3 4.2 3 1 1 4 4 4 1 RNA binding motif DUF4485 PF14846.1 CBZ27575.1 - 0.098 12.3 0.0 7.2 6.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4485) Phage_B PF02304.10 CBZ27575.1 - 0.13 12.5 0.1 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 Scaffold protein B SNARE PF05739.14 CBZ27576.1 - 4.3e-06 26.3 0.1 6.1e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 SNARE domain Ketoacyl-synt_C PF02801.17 CBZ27576.1 - 0.077 12.8 0.6 0.72 9.7 0.0 2.0 1 1 1 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain RPAP1_N PF08621.5 CBZ27576.1 - 0.34 10.5 4.6 2 8.0 3.2 2.0 1 1 0 1 1 1 0 RPAP1-like, N-terminal RAMP4 PF06624.7 CBZ27577.1 - 0.00099 18.6 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Telomerase_RBD PF12009.3 CBZ27577.1 - 0.03 14.2 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain ETF PF01012.16 CBZ27579.1 - 1.5e-38 132.0 1.9 2e-38 131.6 1.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF4468 PF14730.1 CBZ27579.1 - 0.11 12.2 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold GTP_EFTU PF00009.22 CBZ27580.1 - 6.6e-49 165.9 0.1 1e-48 165.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CBZ27580.1 - 9.2e-13 47.8 0.0 2.4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus Septin PF00735.13 CBZ27580.1 - 1.1e-05 24.5 0.1 1.9e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CBZ27580.1 - 0.0001 22.2 0.1 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ27580.1 - 0.0028 18.1 0.0 0.0059 17.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 CBZ27580.1 - 0.0034 17.4 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CBZ27580.1 - 0.023 14.5 0.0 0.081 12.7 0.0 2.0 1 0 0 1 1 1 0 Elongation Factor G, domain II RNA_pol_Rpb6 PF01192.17 CBZ27581.1 - 1.6e-09 37.3 0.0 2.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb6 TPR_MLP1_2 PF07926.7 CBZ27583.1 - 0.006 16.3 2.3 0.006 16.3 1.6 2.0 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF1192 PF06698.6 CBZ27583.1 - 0.16 11.7 0.2 0.16 11.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4570 PF15134.1 CBZ27583.1 - 0.49 10.2 3.9 0.51 10.2 0.1 2.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4570) DUF904 PF06005.7 CBZ27583.1 - 1.7 9.0 5.1 3.5 7.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF904) DivIC PF04977.10 CBZ27583.1 - 4.7 6.7 6.4 0.93 9.0 0.2 2.4 2 1 0 2 2 2 0 Septum formation initiator CPSF100_C PF13299.1 CBZ27584.1 - 6.6e-22 78.4 0.7 1.2e-21 77.5 0.0 1.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CBZ27584.1 - 1.8e-09 37.6 0.0 5.9e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 CBZ27584.1 - 0.00056 19.6 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Rotamase_2 PF13145.1 CBZ27584.1 - 0.072 13.7 3.6 0.16 12.5 2.5 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain Peptidase_C12 PF01088.16 CBZ27586.1 - 1.4e-58 197.5 0.0 1.6e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Clathrin PF00637.15 CBZ27587.1 - 9.2e-07 28.5 8.0 0.00018 21.1 0.2 4.7 5 1 1 6 6 6 2 Region in Clathrin and VPS TPR_7 PF13176.1 CBZ27587.1 - 0.41 10.5 10.8 1.3 8.9 0.5 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat DZR PF12773.2 CBZ27587.1 - 1.4 8.8 8.9 4.8 7.0 6.2 2.0 1 0 0 1 1 1 0 Double zinc ribbon Mito_carr PF00153.22 CBZ27588.1 - 4.5e-62 205.7 0.5 6.1e-21 73.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DSPc PF00782.15 CBZ27590.1 - 2.9e-17 62.4 0.1 4.7e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CBZ27590.1 - 7.3e-05 23.0 0.1 0.00019 21.7 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 CBZ27590.1 - 9.4e-05 21.8 0.3 0.00013 21.3 0.2 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CBZ27590.1 - 0.0001 21.8 0.0 0.00017 21.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 CBZ27590.1 - 0.0011 19.0 0.1 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF442 PF04273.8 CBZ27590.1 - 0.01 15.6 0.1 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Y_phosphatase2 PF03162.8 CBZ27590.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Bud13 PF09736.4 CBZ27591.1 - 2.9e-06 27.6 0.0 4.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex Dynein_light PF01221.13 CBZ27593.1 - 3.1e-37 126.4 0.1 3.3e-37 126.3 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 N_NLPC_P60 PF12912.2 CBZ27593.1 - 0.14 12.2 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term DUF972 PF06156.8 CBZ27594.1 - 0.014 15.7 1.6 0.014 15.7 1.1 7.6 5 2 2 8 8 8 0 Protein of unknown function (DUF972) DUF4650 PF15509.1 CBZ27595.1 - 0.028 13.3 1.4 0.044 12.7 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) V_ATPase_I PF01496.14 CBZ27595.1 - 0.17 9.7 4.1 0.25 9.1 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.4 CBZ27595.1 - 0.21 11.4 22.8 0.022 14.6 8.8 2.6 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 CBZ27595.1 - 1.1 9.0 4.1 36 4.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.6 CBZ27595.1 - 5.5 6.9 6.0 2.7 7.9 1.2 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CALCOCO1 PF07888.6 CBZ27595.1 - 7.7 4.6 19.1 0.14 10.4 7.7 1.8 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like RRM_1 PF00076.17 CBZ27596.1 - 3.5e-05 23.3 1.0 0.0016 18.0 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27596.1 - 0.012 15.5 0.0 0.058 13.3 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATP_bind_4 PF01902.12 CBZ27597.1 - 9.6e-29 100.2 0.0 6.7e-23 81.1 0.0 2.9 2 1 0 2 2 2 2 ATP-binding region FTR PF01913.13 CBZ27598.1 - 0.028 14.1 0.1 0.029 14.1 0.1 1.1 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase B9-C2 PF07162.6 CBZ27600.1 - 8.2e-47 159.0 0.1 9.3e-47 158.9 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SPRY PF00622.23 CBZ27601.1 - 0.00022 21.2 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain zf-RING_2 PF13639.1 CBZ27602.1 - 1.9e-10 40.3 11.5 5.5e-10 38.9 7.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CBZ27602.1 - 1.5e-05 24.9 5.8 1.5e-05 24.9 4.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CBZ27602.1 - 0.00016 21.3 8.8 0.00016 21.3 6.1 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 CBZ27602.1 - 0.00024 20.8 4.8 0.00057 19.6 3.3 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CBZ27602.1 - 0.0018 17.9 10.4 0.0043 16.6 7.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ27602.1 - 0.013 15.4 10.9 0.013 15.4 7.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1308 PF07000.6 CBZ27603.1 - 6.4e-132 439.5 0.0 7.8e-132 439.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) DUF3847 PF12958.2 CBZ27604.1 - 0.09 12.5 0.4 0.17 11.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) Fcf2 PF08698.6 CBZ27605.1 - 2e-21 75.8 1.2 2e-21 75.8 0.9 1.9 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing DUF2407_C PF13373.1 CBZ27605.1 - 0.24 11.3 1.1 0.3 10.9 0.5 1.5 1 1 0 1 1 1 0 DUF2407 C-terminal domain Lsr2 PF11774.3 CBZ27605.1 - 2.3 8.1 8.0 2.9 7.8 2.4 2.1 2 0 0 2 2 2 0 Lsr2 SUI1 PF01253.17 CBZ27609.1 - 6.5e-19 67.5 0.0 6.5e-19 67.5 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 DUF4630 PF15443.1 CBZ27609.1 - 1 9.1 7.2 0.074 12.8 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4630) Baculo_PEP_C PF04513.7 CBZ27610.1 - 0.96 9.2 43.3 0.15 11.8 7.3 6.9 4 1 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.27 CBZ27611.1 - 1.1e-50 167.8 14.9 7.7e-10 38.2 0.0 9.3 9 0 0 9 9 9 6 WD domain, G-beta repeat Utp13 PF08625.6 CBZ27611.1 - 7.7e-39 132.5 0.6 1.2e-38 131.8 0.4 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CBZ27611.1 - 0.016 13.3 7.8 1.4 6.9 0.3 4.0 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Utp12 PF04003.7 CBZ27611.1 - 0.017 15.0 0.2 0.05 13.5 0.1 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family Nucleoporin_N PF08801.6 CBZ27611.1 - 0.066 11.9 2.9 1.3 7.6 0.3 3.6 2 1 0 2 2 2 0 Nup133 N terminal like TFIIB PF00382.14 CBZ27612.1 - 3.5e-23 81.1 0.1 1.6e-11 43.8 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CBZ27612.1 - 0.0069 15.6 0.1 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding MMR_HSR1 PF01926.18 CBZ27613.1 - 2e-13 50.3 0.0 3.8e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ27613.1 - 7.2e-08 31.8 0.0 3.6e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 CBZ27613.1 - 3.8e-06 26.1 0.0 8.6e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBZ27613.1 - 0.00068 19.4 0.4 0.1 12.3 0.1 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 CBZ27613.1 - 0.003 16.6 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 CBZ27613.1 - 0.0043 16.2 0.0 0.0071 15.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 CBZ27613.1 - 0.073 13.0 0.6 0.48 10.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Kringle PF00051.13 CBZ27615.1 - 3.4e-12 46.2 0.1 2.1e-11 43.7 0.1 2.2 2 0 0 2 2 2 1 Kringle domain CHB_HEX_C_1 PF13290.1 CBZ27615.1 - 0.077 12.7 0.0 0.077 12.7 0.0 4.3 3 1 1 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain CHB_HEX_C PF03174.8 CBZ27615.1 - 0.5 10.2 10.6 0.088 12.6 0.7 4.2 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain Myosin_head PF00063.16 CBZ27616.1 - 0.00031 18.9 0.0 0.00065 17.8 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) RRM_1 PF00076.17 CBZ27617.1 - 1.1e-21 76.2 0.0 1.4e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27617.1 - 1.5e-15 56.8 0.0 2.2e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27617.1 - 3.2e-13 49.3 0.0 4.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ27618.1 - 9.7e-22 76.3 0.0 1.3e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27618.1 - 1.4e-15 57.0 0.0 2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27618.1 - 2.9e-13 49.4 0.0 4.5e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ27620.1 - 9.1e-19 66.8 0.6 2.2e-18 65.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27620.1 - 1e-10 41.4 0.0 2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27620.1 - 7e-09 35.3 0.5 1.2e-08 34.6 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.18 CBZ27621.1 - 1.8e-49 168.6 3.5 2.5e-49 168.1 2.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ27621.1 - 6.7e-33 113.8 0.0 1.2e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CBZ27621.1 - 2.4e-05 23.6 0.0 0.033 13.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CBZ27621.1 - 0.00026 21.0 0.3 0.00095 19.2 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 CBZ27621.1 - 0.0011 18.9 0.0 0.13 12.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ27621.1 - 0.0022 18.1 0.5 0.034 14.2 0.3 2.6 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 CBZ27621.1 - 0.0034 16.0 0.2 0.0064 15.1 0.1 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA PF00004.24 CBZ27621.1 - 0.0037 17.4 0.1 0.047 13.8 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ27621.1 - 0.0081 15.8 0.0 0.16 11.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBZ27621.1 - 0.016 14.6 0.1 0.38 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CBZ27621.1 - 0.019 14.1 0.0 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ27621.1 - 0.023 14.2 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.1 CBZ27621.1 - 0.025 14.5 0.1 0.093 12.6 0.1 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 CBZ27621.1 - 0.028 13.5 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 CBZ27621.1 - 0.051 14.3 0.0 0.11 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBZ27621.1 - 0.096 12.1 0.1 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 CBZ27621.1 - 0.13 12.0 0.2 0.35 10.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function DUF87 LSM14 PF12701.2 CBZ27622.1 - 8.9e-33 111.9 0.1 1.4e-32 111.3 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 CBZ27622.1 - 2.1e-05 24.9 18.6 0.0075 16.7 11.0 2.7 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.1 CBZ27622.1 - 3.9e-05 23.5 0.1 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain DnaJ PF00226.26 CBZ27624.1 - 0.00011 21.8 0.2 0.0002 20.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain AvrPphF-ORF-2 PF09143.5 CBZ27624.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AvrPphF-ORF-2 Y_phosphatase2 PF03162.8 CBZ27625.1 - 1.4e-35 122.0 0.0 3.2e-27 94.9 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CBZ27625.1 - 9.2e-05 22.7 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Ins_beta PF03488.9 CBZ27626.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type Seryl_tRNA_N PF02403.17 CBZ27627.1 - 0.057 13.4 0.1 0.067 13.2 0.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2475 PF10629.4 CBZ27628.1 - 0.0057 16.8 1.1 0.019 15.1 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2475) zf-C4H2 PF10146.4 CBZ27628.1 - 0.48 10.3 3.3 0.16 11.9 0.3 1.6 2 0 0 2 2 2 0 Zinc finger-containing protein Raptor_N PF14538.1 CBZ27629.1 - 1.3e-48 164.7 0.0 2.4e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 CBZ27629.1 - 1.3e-05 24.9 1.5 0.082 13.0 0.1 3.3 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.1 CBZ27629.1 - 0.00034 20.8 0.5 0.023 14.9 0.0 2.4 1 1 1 2 2 2 2 HEAT repeats DUF3554 PF12074.3 CBZ27629.1 - 0.26 10.6 0.4 0.45 9.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3554) RNA_pol_Rpb2_6 PF00562.23 CBZ27630.1 - 1.2e-94 317.2 0.0 1.7e-94 316.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpa2_4 PF06883.7 CBZ27630.1 - 1.9e-17 62.9 0.0 4.9e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 CBZ27630.1 - 7.7e-16 57.6 0.0 3.2e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 CBZ27630.1 - 2.9e-13 49.8 0.0 8.7e-13 48.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_1 PF04563.10 CBZ27630.1 - 4.3e-08 32.3 0.0 1.3e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase beta subunit zf-ribbon_3 PF13248.1 CBZ27630.1 - 0.14 11.3 0.4 0.49 9.6 0.3 2.0 1 0 0 1 1 1 0 zinc-ribbon domain PPR PF01535.15 CBZ27631.1 - 0.00011 21.8 0.3 0.00091 19.0 0.0 2.4 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.1 CBZ27631.1 - 0.0002 21.2 0.6 0.0016 18.4 0.0 2.7 2 1 1 3 3 3 1 PPR repeat family PPR_1 PF12854.2 CBZ27631.1 - 0.0047 16.3 0.1 0.015 14.7 0.1 2.0 1 0 0 1 1 1 1 PPR repeat GTSE1_N PF15259.1 CBZ27632.1 - 0.039 13.9 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 zf-AN1 PF01428.11 CBZ27633.1 - 0.013 15.3 27.8 0.039 13.8 6.7 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger ENTH PF01417.15 CBZ27635.1 - 7.2e-27 93.7 0.0 1.1e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Alpha_kinase PF02816.13 CBZ27636.1 - 1.8e-52 177.7 0.0 2.8e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family SpoIID PF08486.5 CBZ27636.1 - 1.6 9.0 5.8 3.3 8.0 4.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein SCAMP PF04144.8 CBZ27639.1 - 5.9e-25 88.1 7.9 1e-24 87.4 5.5 1.3 1 0 0 1 1 1 1 SCAMP family FtsL PF04999.8 CBZ27639.1 - 8.5 6.1 9.0 0.14 11.9 0.2 2.3 3 0 0 3 3 3 0 Cell division protein FtsL eIF-5a PF01287.15 CBZ27641.1 - 7.5e-25 86.6 0.0 1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 CBZ27641.1 - 0.0012 18.6 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 CBZ27641.1 - 0.054 13.2 0.4 0.054 13.2 0.3 1.8 2 0 0 2 2 2 0 KOW motif eIF-5a PF01287.15 CBZ27642.1 - 7.5e-25 86.6 0.0 1e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 CBZ27642.1 - 0.0012 18.6 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain KOW PF00467.24 CBZ27642.1 - 0.054 13.2 0.4 0.054 13.2 0.3 1.8 2 0 0 2 2 2 0 KOW motif SNF2_N PF00176.18 CBZ27643.1 - 3.9e-63 213.0 0.2 6.9e-33 113.7 0.0 3.0 2 1 0 2 2 2 2 SNF2 family N-terminal domain zf-PARP PF00645.13 CBZ27643.1 - 1.2e-15 57.4 0.2 3.6e-15 55.9 0.1 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.26 CBZ27643.1 - 5.3e-14 51.8 0.0 2.3e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CBZ27643.1 - 5.4e-08 32.5 4.3 5.4e-08 32.5 3.0 2.9 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ27643.1 - 0.0001 21.8 3.2 0.0001 21.8 2.2 3.5 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ27643.1 - 0.00045 20.2 1.1 0.0017 18.4 0.7 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger ResIII PF04851.10 CBZ27643.1 - 0.0038 17.0 0.0 4.3 7.1 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 CBZ27643.1 - 0.0059 16.3 4.0 0.0059 16.3 2.8 4.0 5 0 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CBZ27643.1 - 0.0077 16.2 3.9 0.0077 16.2 2.7 3.4 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBZ27643.1 - 0.0091 15.8 1.1 0.041 13.7 0.8 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DEAD_2 PF06733.10 CBZ27643.1 - 0.12 11.8 2.3 27 4.0 0.0 3.4 3 0 0 3 3 3 0 DEAD_2 PP2C PF00481.16 CBZ27644.1 - 1.4e-52 178.6 0.1 1.8e-52 178.2 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ27644.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CBZ27644.1 - 0.0015 18.2 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) TIP39 PF14980.1 CBZ27644.1 - 0.019 14.5 0.0 0.047 13.3 0.0 1.6 1 0 0 1 1 1 0 TIP39 peptide Luciferase_N PF05295.6 CBZ27644.1 - 0.031 14.0 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain Shisa PF13908.1 CBZ27646.1 - 1.1 9.4 9.9 0.13 12.4 3.6 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Shisa PF13908.1 CBZ27647.1 - 1.9 8.6 7.0 0.59 10.2 2.7 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ank_2 PF12796.2 CBZ27648.1 - 1.2e-08 35.2 0.3 0.00044 20.5 0.0 4.6 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ27648.1 - 7e-08 32.7 1.9 0.0036 17.7 0.0 4.7 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ27648.1 - 0.0005 20.0 0.4 0.035 14.3 0.0 4.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 CBZ27648.1 - 0.0012 19.0 5.7 0.0015 18.6 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 CBZ27648.1 - 0.0015 18.1 1.6 0.008 15.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Imm29 PF15575.1 CBZ27648.1 - 0.043 13.4 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 0 Immunity protein 29 zf-DNL PF05180.7 CBZ27649.1 - 5.6e-29 99.6 0.1 8.8e-29 99.0 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_5 PF13719.1 CBZ27649.1 - 0.052 13.1 0.2 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBZ27649.1 - 0.054 13.1 0.2 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 CBZ27649.1 - 0.074 12.6 0.3 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain HET-s_218-289 PF11558.3 CBZ27649.1 - 0.084 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Het-s 218-289 Cyclin_N PF00134.18 CBZ27650.1 - 1.1e-06 28.2 0.4 0.0018 17.8 0.0 3.4 3 0 0 3 3 3 2 Cyclin, N-terminal domain Prefoldin_2 PF01920.15 CBZ27651.1 - 8.7e-11 41.5 0.8 1.1e-10 41.2 0.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 CBZ27651.1 - 0.00012 21.7 2.5 0.026 14.1 0.2 2.1 2 0 0 2 2 2 2 Prefoldin subunit HR1 PF02185.11 CBZ27651.1 - 0.0049 16.5 1.1 0.39 10.4 0.0 2.2 2 0 0 2 2 2 1 Hr1 repeat FlaC_arch PF05377.6 CBZ27651.1 - 0.013 15.4 0.4 2.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 CBZ27651.1 - 0.05 12.0 0.2 0.06 11.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_13 PF13166.1 CBZ27651.1 - 0.065 11.6 0.2 0.08 11.3 0.1 1.0 1 0 0 1 1 1 0 AAA domain DUF4140 PF13600.1 CBZ27651.1 - 0.066 13.6 1.1 8.3 6.9 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tropomyosin_1 PF12718.2 CBZ27651.1 - 0.081 12.7 3.9 2.1 8.1 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin like Med9 PF07544.8 CBZ27651.1 - 0.084 12.6 1.2 10 5.9 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.7 CBZ27651.1 - 0.085 12.6 0.1 0.33 10.7 0.1 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.8 CBZ27651.1 - 0.11 13.2 0.2 1.4 9.6 0.0 2.0 2 0 0 2 2 2 0 Occludin homology domain DUF904 PF06005.7 CBZ27651.1 - 0.13 12.5 2.8 0.82 9.9 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Striatin PF08232.7 CBZ27651.1 - 0.18 12.0 2.3 7 6.9 1.5 2.0 1 1 1 2 2 2 0 Striatin family TBPIP PF07106.8 CBZ27651.1 - 0.2 11.1 2.7 1.2 8.6 0.3 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Ead_Ea22 PF13935.1 CBZ27651.1 - 0.22 11.8 1.4 0.29 11.4 0.9 1.3 1 1 0 1 1 1 0 Ead/Ea22-like protein Enkurin PF13864.1 CBZ27651.1 - 0.24 11.5 1.7 5.2 7.3 0.2 2.2 2 0 0 2 2 2 0 Calmodulin-binding IncA PF04156.9 CBZ27651.1 - 0.47 10.0 5.5 15 5.1 3.5 2.0 1 1 0 1 1 1 0 IncA protein CCDC-167 PF15188.1 CBZ27651.1 - 0.49 10.3 5.8 24 4.9 4.0 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Kdo PF06293.9 CBZ27656.1 - 3e-06 26.4 0.0 0.0032 16.5 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBZ27656.1 - 0.0006 19.2 0.0 0.88 8.8 0.0 2.2 1 1 1 2 2 2 2 RIO1 family APH PF01636.18 CBZ27656.1 - 0.00094 18.9 0.1 0.0039 16.9 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CBZ27656.1 - 0.0031 16.7 0.0 0.012 14.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27656.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase LRR_8 PF13855.1 CBZ27657.1 - 1e-17 63.5 5.6 1.2e-14 53.7 0.2 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CBZ27657.1 - 1.6e-12 46.7 3.3 1.5e-06 27.7 0.4 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ27657.1 - 2.9e-06 26.5 6.0 0.052 13.5 0.1 4.7 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 CBZ27657.1 - 9.6e-05 22.0 2.1 0.085 12.9 0.0 4.1 3 0 0 3 3 3 1 Leucine Rich repeat LRR_7 PF13504.1 CBZ27657.1 - 0.00046 19.9 5.2 2.1 8.8 0.2 5.1 5 0 0 5 5 5 2 Leucine rich repeat LRR_9 PF14580.1 CBZ27657.1 - 0.013 15.0 0.1 0.046 13.2 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat Ribosomal_L23 PF00276.15 CBZ27658.1 - 0.00056 19.7 0.4 0.00086 19.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 OAD_gamma PF04277.8 CBZ27659.1 - 0.033 14.5 0.1 5.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4293 PF14126.1 CBZ27659.1 - 0.095 12.6 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF4131 PF13567.1 CBZ27659.1 - 0.23 10.8 0.1 0.23 10.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Pro_isomerase PF00160.16 CBZ27660.1 - 1.5e-43 148.6 0.0 1.7e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SLBP_RNA_bind PF15247.1 CBZ27661.1 - 1.2e-13 50.5 0.1 5.9e-13 48.3 0.0 2.1 1 1 1 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain Ank_4 PF13637.1 CBZ27662.1 - 7.3e-24 83.7 0.5 1.1e-11 44.8 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CBZ27662.1 - 1.9e-20 71.5 3.5 6.4e-08 32.0 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 CBZ27662.1 - 1.7e-19 69.9 0.0 6.5e-10 39.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBZ27662.1 - 2.5e-19 68.8 8.2 1.3e-09 38.0 0.1 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ27662.1 - 3.4e-14 51.5 0.3 6e-05 22.9 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat zf-RVT PF13966.1 CBZ27662.1 - 0.078 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase TFIIA PF03153.8 CBZ27663.1 - 0.065 13.1 8.3 0.12 12.2 5.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PUB PF09409.5 CBZ27664.1 - 0.043 13.5 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 PUB domain Tubulin PF00091.20 CBZ27665.1 - 2.7e-72 243.1 0.0 3.8e-72 242.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ27665.1 - 2.7e-44 150.2 0.2 2.7e-44 150.2 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBZ27665.1 - 3.8e-06 26.9 0.0 1.4e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.1 CBZ27665.1 - 0.033 13.1 0.0 0.049 12.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin like EF-hand_7 PF13499.1 CBZ27666.1 - 5.1e-05 23.3 0.0 0.03 14.4 0.0 3.8 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.1 CBZ27666.1 - 0.018 14.6 0.0 0.093 12.3 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 CBZ27666.1 - 0.029 14.2 0.0 6.5 6.9 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 CBZ27666.1 - 0.14 11.4 0.0 1.1 8.7 0.0 2.4 3 0 0 3 3 3 0 EF hand Dynein_heavy PF03028.10 CBZ27667.1 - 7.9e-175 582.8 1.7 2.9e-174 580.9 0.0 2.7 2 1 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 CBZ27667.1 - 6.4e-127 424.3 13.0 6.4e-127 424.3 9.0 3.9 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CBZ27667.1 - 3.1e-116 388.2 0.7 3.1e-116 388.2 0.5 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ27667.1 - 7.1e-92 307.1 0.0 1.6e-91 305.9 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ27667.1 - 4.2e-72 242.3 0.0 8.5e-72 241.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ27667.1 - 7.4e-55 185.2 1.6 1.8e-54 183.9 1.1 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBZ27667.1 - 6.9e-41 140.1 0.0 1.6e-40 138.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CBZ27667.1 - 4.6e-38 130.8 8.8 4.6e-38 130.8 6.1 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ27667.1 - 3e-14 52.9 0.0 0.002 17.8 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ27667.1 - 1.5e-06 28.4 1.5 0.034 14.3 0.0 5.4 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ27667.1 - 0.0024 18.6 0.1 0.15 12.8 0.0 4.0 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 CBZ27667.1 - 0.023 14.8 3.1 10 6.2 0.0 5.5 6 0 0 6 6 5 0 AAA domain Complex1_LYR PF05347.10 CBZ27668.1 - 1.1e-05 25.1 0.0 2.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBZ27668.1 - 0.00017 21.7 0.1 0.00041 20.4 0.0 1.7 2 0 0 2 2 2 1 Complex1_LYR-like 2OG-FeII_Oxy PF03171.15 CBZ27670.1 - 9.6e-12 45.0 0.0 2.5e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 CBZ27670.1 - 0.011 16.2 0.0 0.64 10.5 0.0 2.5 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal SecE PF00584.15 CBZ27671.1 - 8.3e-14 50.9 0.6 9.5e-14 50.7 0.4 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CobD_Cbib PF03186.8 CBZ27671.1 - 0.014 14.4 0.0 0.015 14.3 0.0 1.0 1 0 0 1 1 1 0 CobD/Cbib protein NAD_binding_2 PF03446.10 CBZ27672.1 - 4.6e-32 111.1 0.1 7.4e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CBZ27672.1 - 6.7e-13 48.7 0.3 2e-11 44.0 0.1 2.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 CBZ27672.1 - 0.00083 19.7 0.2 0.0067 16.8 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Minor_capsid_1 PF10665.4 CBZ27672.1 - 0.0012 18.7 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Minor capsid protein GFO_IDH_MocA PF01408.17 CBZ27672.1 - 0.0094 16.4 0.0 0.78 10.2 0.0 2.8 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.13 CBZ27672.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NPV_P10 PF05531.7 CBZ27674.1 - 0.04 14.1 1.6 0.14 12.3 0.1 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 CBZ27674.1 - 2 7.9 12.1 0.23 11.0 0.4 2.3 2 0 0 2 2 2 0 IncA protein GAS PF13851.1 CBZ27674.1 - 3.1 6.9 8.3 1.2 8.3 0.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TEX13 PF15186.1 CBZ27674.1 - 7 6.2 9.6 0.39 10.2 0.7 2.4 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Frataxin_Cyay PF01491.11 CBZ27675.1 - 2e-28 98.3 0.0 2.5e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain DUF1886 PF09171.5 CBZ27676.1 - 0.00084 18.4 4.2 35 3.3 0.0 5.1 1 1 2 5 5 5 5 Domain of unknown function (DUF1886) Prefoldin_3 PF13758.1 CBZ27676.1 - 0.0068 16.1 25.5 24 4.7 0.1 10.8 2 1 13 15 15 15 5 Prefoldin subunit RRM_5 PF13893.1 CBZ27678.1 - 0.00017 21.3 0.0 0.00027 20.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2652 PF10851.3 CBZ27678.1 - 0.00039 20.4 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2652) RRM_6 PF14259.1 CBZ27678.1 - 0.00042 20.2 0.1 0.0011 18.9 0.0 1.7 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ27678.1 - 0.00051 19.6 0.1 0.00099 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CorA PF01544.13 CBZ27679.1 - 8.1e-19 67.7 0.0 1.9e-18 66.5 0.0 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CTDII PF01556.13 CBZ27680.1 - 1.3e-22 79.4 0.0 4.3e-22 77.7 0.0 1.9 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 CBZ27680.1 - 6.1e-18 64.3 0.4 1.2e-17 63.4 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CBZ27680.1 - 3.9e-16 58.8 12.8 6.3e-16 58.1 8.8 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF879 PF05947.7 CBZ27680.1 - 0.064 11.6 0.0 0.096 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) DZR PF12773.2 CBZ27680.1 - 0.5 10.2 11.8 9.4 6.1 8.2 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 CBZ27680.1 - 0.6 10.1 11.4 1.4 8.9 0.5 3.5 2 1 1 3 3 3 0 zinc-finger Prok-RING_1 PF14446.1 CBZ27680.1 - 2 8.2 11.4 0.21 11.3 1.1 2.5 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 Ogr_Delta PF04606.7 CBZ27680.1 - 2.2 8.0 6.5 9.6 5.9 0.0 3.3 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger HypA PF01155.14 CBZ27680.1 - 5.1 6.8 10.9 1.1 8.9 1.4 2.3 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-CCHC_5 PF14787.1 CBZ27680.1 - 9.9 5.7 12.2 0.081 12.4 2.2 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Kelch_4 PF13418.1 CBZ27681.1 - 2e-06 27.4 3.8 0.0002 21.0 0.0 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CBZ27681.1 - 0.013 15.0 0.0 0.2 11.2 0.0 2.6 2 0 0 2 2 2 0 Kelch motif DUF4197 PF13852.1 CBZ27681.1 - 1.6 8.2 0.0 3.1 7.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) Lebercilin PF15619.1 CBZ27681.1 - 3 7.2 1.8 5.3 6.4 1.3 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Angiomotin_C PF12240.3 CBZ27681.1 - 8 5.9 4.8 23 4.4 3.3 1.7 1 0 0 1 1 1 0 Angiomotin C terminal Aldedh PF00171.17 CBZ27682.1 - 9.5e-179 594.5 0.3 1.1e-178 594.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CBZ27682.1 - 0.061 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) SBP_bac_3 PF00497.15 CBZ27683.1 - 0.0027 16.9 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 SMI1_KNR4 PF09346.5 CBZ27684.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Mec-17 PF05301.6 CBZ27685.1 - 3.2e-33 114.2 0.0 4.6e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Touch receptor neuron protein Mec-17 Acetyltransf_1 PF00583.19 CBZ27685.1 - 0.0011 18.9 0.0 0.0034 17.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ27685.1 - 0.092 12.9 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain LMBR1 PF04791.11 CBZ27686.1 - 3.5e-27 95.1 26.7 1.2e-15 57.1 6.0 2.1 2 0 0 2 2 2 2 LMBR1-like membrane protein DUF2721 PF11026.3 CBZ27686.1 - 0.49 10.0 0.0 0.49 10.0 0.0 5.7 4 2 2 6 6 6 0 Protein of unknown function (DUF2721) Sigma_reg_N PF13800.1 CBZ27686.1 - 0.77 9.8 9.8 4.8 7.2 0.5 3.5 3 0 0 3 3 3 0 Sigma factor regulator N-terminal ATP-synt_ab PF00006.20 CBZ27687.1 - 1.2e-64 217.8 0.1 1.1e-63 214.5 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBZ27687.1 - 8.6e-22 77.7 0.3 1.5e-21 76.9 0.2 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBZ27687.1 - 1.6e-13 50.6 0.2 3.8e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 CBZ27687.1 - 0.0014 18.0 1.0 0.0059 16.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 CBZ27687.1 - 0.0042 17.2 0.1 0.029 14.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 CBZ27687.1 - 0.0047 16.0 0.1 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 KaiC DUF258 PF03193.11 CBZ27687.1 - 0.054 12.6 0.1 0.095 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 CBZ27687.1 - 0.22 10.3 0.5 0.36 9.6 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.20 CBZ27688.1 - 5.9e-64 215.5 0.0 1e-63 214.7 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 CBZ27688.1 - 1.7e-13 50.5 0.2 3.5e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 CBZ27688.1 - 3e-07 30.9 0.0 5.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain AAA_25 PF13481.1 CBZ27688.1 - 0.0022 17.4 0.1 0.0054 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 CBZ27688.1 - 0.0049 16.0 0.1 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 KaiC AAA PF00004.24 CBZ27688.1 - 0.013 15.7 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CBZ27688.1 - 0.051 12.7 0.1 0.088 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ribosomal_S25 PF03297.10 CBZ27689.1 - 2.9e-43 146.1 3.9 3.4e-43 145.9 2.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.3 CBZ27689.1 - 0.092 11.5 0.2 0.096 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) DNA_methylase PF00145.12 CBZ27690.1 - 6e-38 130.8 0.0 1.4e-29 103.2 0.0 3.6 2 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase WD40 PF00400.27 CBZ27691.1 - 0.00034 20.3 0.1 0.088 12.7 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_3 PF13570.1 CBZ27691.1 - 0.0042 17.2 1.2 1.2 9.5 0.1 4.6 4 0 0 4 4 4 1 PQQ-like domain Surfac_D-trimer PF09006.6 CBZ27696.1 - 0.17 11.6 0.5 1.6 8.5 0.5 2.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Cullin PF00888.17 CBZ27697.1 - 2.7e-40 138.5 0.0 3.5e-30 105.1 0.0 2.0 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 CBZ27697.1 - 2.5e-14 52.8 0.0 8e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain NPL4 PF05021.10 CBZ27698.1 - 6.2e-22 78.1 0.0 2.6e-21 76.0 0.0 1.8 1 1 0 1 1 1 1 NPL4 family PRP38 PF03371.10 CBZ27699.1 - 2.2e-05 24.1 0.0 3.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 PRP38 family MbeB_N PF04837.7 CBZ27699.1 - 0.034 14.2 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Spore_YtfJ PF09579.5 CBZ27699.1 - 3.2 7.6 0.0 3.2 7.6 0.0 3.1 3 0 0 3 3 3 0 Sporulation protein YtfJ (Spore_YtfJ) PPP4R2 PF09184.6 CBZ27700.1 - 0.0038 16.8 0.0 0.0064 16.0 0.0 1.3 1 0 0 1 1 1 1 PPP4R2 RNA_pol_N PF01194.12 CBZ27701.1 - 1.8e-28 98.3 0.7 2.2e-28 98.0 0.5 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Yippee-Mis18 PF03226.9 CBZ27701.1 - 0.12 12.4 0.5 0.13 12.2 0.2 1.3 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Metallophos PF00149.23 CBZ27702.1 - 1.8e-41 141.7 1.6 2.5e-41 141.3 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GIY-YIG PF01541.19 CBZ27703.1 - 1.2e-06 28.7 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.4 CBZ27703.1 - 0.052 13.9 0.0 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 T5orf172 domain Sec23_trunk PF04811.10 CBZ27704.1 - 1.7e-38 132.3 0.0 2.8e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 CBZ27704.1 - 4.7e-17 62.2 0.1 9.1e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 CBZ27704.1 - 1.4e-16 59.7 0.0 2.4e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CBZ27704.1 - 1.3e-13 50.2 1.9 4.5e-13 48.5 1.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger DUF1034 PF06280.7 CBZ27705.1 - 0.099 13.0 0.1 4.2 7.8 0.0 3.9 4 0 0 4 4 4 0 Fn3-like domain (DUF1034) PAT1 PF09770.4 CBZ27705.1 - 9.3 4.3 13.2 20 3.2 9.2 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TAP42 PF04177.7 CBZ27707.1 - 3.6e-28 98.5 14.7 7.7e-15 54.6 12.4 2.6 2 1 0 2 2 2 2 TAP42-like family DUF3682 PF12446.3 CBZ27707.1 - 0.027 14.7 1.2 0.027 14.7 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3682) ATP_bind_1 PF03029.12 CBZ27709.1 - 1.5e-60 204.7 0.0 1.7e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CBZ27709.1 - 1e-05 26.3 0.0 1.8e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBZ27709.1 - 0.00051 19.5 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 CBZ27709.1 - 0.00089 19.4 0.0 0.0014 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CBZ27709.1 - 0.0014 18.9 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.1 CBZ27709.1 - 0.0017 18.6 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CBZ27709.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CBZ27709.1 - 0.0022 17.4 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 CBZ27709.1 - 0.0027 17.4 0.0 0.0049 16.6 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CBZ27709.1 - 0.0042 16.5 0.2 0.023 14.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CBZ27709.1 - 0.0054 16.6 0.0 0.021 14.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CBZ27709.1 - 0.0064 15.9 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 CBZ27709.1 - 0.017 14.6 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 CBZ27709.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 CBZ27709.1 - 0.023 14.1 0.0 0.048 13.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 CBZ27709.1 - 0.035 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 CBZ27709.1 - 0.036 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CBZ27709.1 - 0.037 13.5 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBZ27709.1 - 0.039 14.1 0.1 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DUF258 PF03193.11 CBZ27709.1 - 0.055 12.6 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 CBZ27709.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBZ27709.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 CBZ27709.1 - 0.13 11.2 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain GTP_EFTU PF00009.22 CBZ27709.1 - 0.14 11.5 0.0 2.8 7.3 0.0 2.4 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.9 CBZ27709.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 CBZ27709.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Surp PF01805.15 CBZ27710.1 - 2.7e-14 52.5 1.9 7.8e-11 41.4 0.1 2.3 2 0 0 2 2 2 2 Surp module DUF2362 PF10154.4 CBZ27710.1 - 0.13 10.8 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) OHCU_decarbox PF09349.5 CBZ27710.1 - 0.24 11.6 2.5 0.44 10.8 0.2 2.4 2 1 1 3 3 3 0 OHCU decarboxylase DNA_pol_E_B PF04042.11 CBZ27711.1 - 2.5e-27 95.5 1.4 1.2e-24 86.7 1.0 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Ras PF00071.17 CBZ27712.1 - 1.5e-50 170.7 0.0 1.9e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ27712.1 - 6.4e-17 62.1 0.0 1.2e-16 61.2 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CBZ27712.1 - 4.4e-11 42.3 0.0 5.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 CBZ27712.1 - 0.00027 21.0 0.2 0.0017 18.4 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 CBZ27712.1 - 0.00037 19.6 0.0 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.14 CBZ27712.1 - 0.015 14.7 0.1 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 CBZ27712.1 - 0.026 13.1 1.6 1 7.9 0.1 2.9 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 CBZ27712.1 - 0.027 14.5 0.2 0.28 11.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.22 CBZ27712.1 - 0.033 13.6 0.6 0.3 10.5 0.4 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CBZ27712.1 - 0.037 13.9 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 CBZ27712.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein ATP_bind_1 PF03029.12 CBZ27712.1 - 0.12 11.8 0.4 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 CBZ27712.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Septin PduV-EutP PF10662.4 CBZ27712.1 - 0.14 11.6 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KaiC PF06745.8 CBZ27712.1 - 0.17 11.0 0.1 0.36 9.8 0.1 1.5 1 1 0 1 1 1 0 KaiC Cluap1 PF10234.4 CBZ27713.1 - 1.3e-100 336.0 12.9 1.7e-100 335.6 8.9 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lectin_N PF03954.9 CBZ27713.1 - 0.041 13.2 3.4 0.039 13.3 0.6 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain BRE1 PF08647.6 CBZ27713.1 - 1.5 8.8 22.2 0.037 14.0 6.6 2.9 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase She9_MDM33 PF05546.6 CBZ27713.1 - 6.8 6.1 16.6 1.6 8.2 9.0 1.7 2 0 0 2 2 2 0 She9 / Mdm33 family RNase_T PF00929.19 CBZ27714.1 - 4.1e-05 23.9 0.0 6.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF1295 PF06966.7 CBZ27716.1 - 2.3e-09 36.8 1.3 3.2e-09 36.4 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CBZ27716.1 - 6.3e-05 23.0 1.2 6.3e-05 23.0 0.8 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 CBZ27716.1 - 0.00071 19.3 1.8 0.00076 19.2 0.5 1.7 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Rod_cone_degen PF15201.1 CBZ27716.1 - 0.032 14.0 1.8 0.055 13.3 0.6 1.8 2 0 0 2 2 2 0 Progressive rod-cone degeneration RF-1 PF00472.15 CBZ27717.1 - 9.1e-32 109.2 0.4 1.7e-31 108.3 0.0 1.7 2 0 0 2 2 2 1 RF-1 domain PCRF PF03462.13 CBZ27717.1 - 4.2e-15 55.4 0.3 8.9e-15 54.4 0.2 1.5 1 0 0 1 1 1 1 PCRF domain SFTA2 PF15210.1 CBZ27717.1 - 0.012 15.1 0.1 7.9 6.1 0.1 2.7 2 0 0 2 2 2 0 Surfactant-associated protein 2 DUF1126 PF06565.7 CBZ27718.1 - 3.4e-31 106.4 0.1 4.2e-10 38.9 0.0 3.8 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_7 PF13499.1 CBZ27718.1 - 0.038 14.1 1.2 1.2 9.3 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain pair IncFII_repA PF02387.10 CBZ27718.1 - 0.25 10.4 4.6 4.6 6.3 0.9 2.2 2 0 0 2 2 2 0 IncFII RepA protein family Cyclin_N PF00134.18 CBZ27719.1 - 1.8e-38 131.0 0.4 2.5e-38 130.5 0.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBZ27719.1 - 5.2e-11 42.5 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain NfI_DNAbd_pre-N PF10524.4 CBZ27719.1 - 0.038 13.6 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Peptidase_C2 PF00648.16 CBZ27720.1 - 1.3e-51 175.3 0.1 2e-51 174.7 0.1 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ27720.1 - 7e-23 80.5 0.1 2.2e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) Leader_Trp PF08255.6 CBZ27720.1 - 9 6.2 7.3 54 3.8 1.5 3.7 3 0 0 3 3 3 0 Trp-operon Leader Peptide Rab3-GTPase_cat PF13890.1 CBZ27721.1 - 1.2e-45 154.8 0.1 2.1e-45 154.0 0.1 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit GEMIN8 PF15348.1 CBZ27723.1 - 0.039 14.0 0.3 2.8 7.9 0.3 2.4 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Carb_kinase PF01256.12 CBZ27723.1 - 0.05 12.8 0.1 0.11 11.7 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate kinase DUF1126 PF06565.7 CBZ27723.1 - 0.15 11.5 0.2 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF1126) PAT1 PF09770.4 CBZ27723.1 - 1.1 7.4 13.2 1.4 7.0 9.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 CBZ27724.1 - 1.8e-44 151.8 0.0 2.5e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27724.1 - 3.1e-30 105.0 0.0 4.3e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ27724.1 - 0.00038 19.5 0.0 0.00062 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ27724.1 - 0.0085 15.8 1.4 0.035 13.8 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family ABC_ATPase PF09818.4 CBZ27726.1 - 5.4e-168 559.2 0.0 7.1e-168 558.8 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 CBZ27726.1 - 0.035 14.4 0.0 0.055 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBZ27726.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain zf-Tim10_DDP PF02953.10 CBZ27727.1 - 1.5e-05 24.1 0.1 2.1e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Pkinase PF00069.20 CBZ27728.1 - 4.1e-29 101.5 0.0 5.2e-16 58.5 0.0 3.6 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27728.1 - 1.2e-06 27.7 0.0 0.21 10.6 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase RIO1 PF01163.17 CBZ27728.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 CBZ27728.1 - 0.17 10.6 0.1 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TRAPPC-Trs85 PF12739.2 CBZ27729.1 - 5.5e-32 110.9 1.8 9.4e-32 110.1 1.3 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_11 PF13414.1 CBZ27729.1 - 0.00013 21.5 2.4 0.0014 18.2 0.2 2.7 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 CBZ27729.1 - 0.019 14.8 5.6 0.27 11.1 0.8 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 CBZ27730.1 - 4.1e-34 117.8 0.1 2.9e-31 108.5 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27730.1 - 5.8e-12 45.2 0.0 1.7e-07 30.5 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBZ27730.1 - 0.014 15.1 0.0 0.088 12.5 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Scm3 PF10384.4 CBZ27730.1 - 0.032 13.7 0.1 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 Centromere protein Scm3 Kinase-like PF14531.1 CBZ27730.1 - 0.067 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like BRCT PF00533.21 CBZ27731.1 - 8.5e-05 22.6 0.0 0.0033 17.5 0.0 3.2 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CBZ27731.1 - 0.027 14.3 0.2 0.9 9.4 0.1 2.9 3 0 0 3 3 3 0 twin BRCT domain WD40 PF00400.27 CBZ27732.1 - 4.3e-18 64.4 12.8 0.088 12.7 0.0 9.9 11 0 0 11 11 11 6 WD domain, G-beta repeat JAB PF01398.16 CBZ27733.1 - 0.00014 21.6 0.0 0.00044 19.9 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DAGAT PF03982.8 CBZ27735.1 - 1.1e-77 260.7 0.1 1.4e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase KOW PF00467.24 CBZ27736.1 - 0.039 13.6 1.2 0.12 12.1 0.9 1.8 1 0 0 1 1 1 0 KOW motif DUF1016 PF06250.6 CBZ27736.1 - 0.067 12.1 0.7 0.11 11.4 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1016) Bclt PF15318.1 CBZ27736.1 - 0.28 11.1 6.3 0.45 10.4 3.7 1.7 1 1 1 2 2 2 0 Putative Bcl-2 like protein of testis COX6B PF02297.12 CBZ27737.1 - 0.0017 18.3 5.8 0.005 16.8 4.1 1.6 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 CBZ27737.1 - 0.0037 17.1 5.0 0.072 13.0 0.4 2.3 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 CBZ27737.1 - 0.36 10.6 3.9 1.8 8.3 0.3 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3716 PF12511.3 CBZ27737.1 - 0.43 10.2 3.2 1.2 8.7 2.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3716) UPF0203 PF05254.7 CBZ27737.1 - 0.7 9.7 6.4 2.3 8.1 4.4 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 CBZ27737.1 - 3.2 7.8 6.2 26 4.9 4.3 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 EFP_N PF08207.7 CBZ27738.1 - 1.9e-05 24.4 0.2 3.1e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain HORMA PF02301.13 CBZ27740.1 - 7.2e-38 130.1 0.0 8.3e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 HORMA domain TPR_12 PF13424.1 CBZ27741.1 - 4.7e-14 52.0 19.0 5.4e-05 23.0 1.7 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ27741.1 - 0.002 17.8 1.6 4.3 7.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ27741.1 - 0.13 12.7 3.2 0.89 10.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.26 CBZ27742.1 - 3.6e-06 26.6 4.9 0.00015 21.4 3.4 2.3 1 1 0 1 1 1 1 DnaJ domain DUF4407 PF14362.1 CBZ27742.1 - 0.00014 20.9 5.3 0.00071 18.6 3.7 1.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4407) HSCB_C PF07743.8 CBZ27742.1 - 0.00066 20.0 1.4 0.0043 17.4 0.0 2.5 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain LRR_4 PF12799.2 CBZ27743.1 - 6.7e-11 41.5 0.8 9.9e-08 31.4 0.2 2.9 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CBZ27743.1 - 3.5e-10 39.7 0.0 6.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 CBZ27743.1 - 3.8e-06 26.5 0.9 3.8e-06 26.5 0.7 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.1 CBZ27743.1 - 0.00051 19.8 0.4 6.1 7.2 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.28 CBZ27743.1 - 0.00051 19.7 2.2 1.4 9.2 0.0 4.2 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 CBZ27743.1 - 0.004 17.1 4.0 0.89 10.0 0.0 3.9 4 0 0 4 4 4 1 Leucine rich repeat LSM PF01423.17 CBZ27744.1 - 4.1e-13 48.6 0.0 5.5e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBZ27744.1 - 0.007 16.2 0.2 0.011 15.6 0.1 1.5 1 1 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 CBZ27744.1 - 0.0077 16.0 0.0 0.013 15.2 0.0 1.3 1 1 0 1 1 1 1 Scd6-like Sm domain Transket_pyr PF02779.19 CBZ27745.1 - 6.7e-44 149.4 0.0 9.6e-44 148.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBZ27745.1 - 2.6e-37 127.5 0.0 6.3e-37 126.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain YycC PF14174.1 CBZ27747.1 - 0.012 15.2 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 YycC-like protein DUF566 PF04484.7 CBZ27747.1 - 0.28 10.6 1.9 0.36 10.3 1.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF1935 PF09149.5 CBZ27749.1 - 2.2e-26 91.8 0.0 2.6e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Rep-A_N PF04057.7 CBZ27750.1 - 0.062 13.1 0.1 0.82 9.5 0.0 2.2 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain Steroid_dh PF02544.11 CBZ27751.1 - 1.5e-25 89.6 2.7 2.5e-25 88.9 1.8 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 CBZ27751.1 - 2.5e-05 23.6 1.1 4.2e-05 22.9 0.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CBZ27751.1 - 0.012 15.6 3.8 0.14 12.2 0.5 2.3 1 1 1 2 2 2 0 Phospholipid methyltransferase Peptidase_M50 PF02163.17 CBZ27751.1 - 0.094 11.6 0.1 4 6.3 0.0 2.7 2 1 1 3 3 3 0 Peptidase family M50 ATP-grasp_4 PF13535.1 CBZ27752.1 - 4e-15 56.0 0.0 1.1e-14 54.6 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CBZ27752.1 - 7.1e-15 54.9 0.0 1.6e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.23 CBZ27752.1 - 1.2e-05 25.6 1.0 3.8e-05 24.0 0.0 2.4 3 0 0 3 3 3 1 SET domain ATP-grasp_3 PF02655.9 CBZ27752.1 - 2.3e-05 24.3 0.0 7.9e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CBZ27752.1 - 0.0001 21.8 0.0 0.00032 20.2 0.0 1.7 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.1 CBZ27752.1 - 0.0028 16.4 0.0 0.53 8.9 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CBZ27752.1 - 0.0036 16.6 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.1 CBZ27752.1 - 0.12 11.4 0.1 0.44 9.5 0.0 1.9 3 0 0 3 3 3 0 Sugar-transfer associated ATP-grasp CHAP PF05257.11 CBZ27753.1 - 2.8e-06 27.0 1.6 0.00064 19.3 0.1 2.4 2 1 0 2 2 2 2 CHAP domain Thioredoxin PF00085.15 CBZ27755.1 - 0.00096 18.7 0.1 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DUF3042 PF11240.3 CBZ27756.1 - 0.81 9.5 5.3 5.1 6.9 3.7 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) SLBP_RNA_bind PF15247.1 CBZ27757.1 - 2.3e-22 78.5 2.6 5.5e-22 77.3 1.8 1.6 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Not3 PF04065.10 CBZ27758.1 - 6.5e-73 244.8 24.1 6.5e-73 244.8 16.7 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CBZ27758.1 - 3.5e-35 120.8 8.2 3.5e-35 120.8 5.7 2.5 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family SOG2 PF10428.4 CBZ27758.1 - 2.3 6.7 17.4 1.2 7.6 1.9 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein WD40 PF00400.27 CBZ27759.1 - 7.4e-21 73.2 1.0 0.0014 18.3 0.0 6.2 6 1 0 6 6 6 5 WD domain, G-beta repeat TPM PF04536.9 CBZ27760.1 - 3.5e-17 62.3 0.0 6.2e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase Thioredoxin_3 PF13192.1 CBZ27760.1 - 0.19 11.5 1.5 17 5.3 0.1 3.6 3 0 0 3 3 3 0 Thioredoxin domain zf-IS66 PF13005.2 CBZ27760.1 - 0.7 9.9 0.0 0.7 9.9 0.0 3.2 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 DUF2387 PF09526.5 CBZ27760.1 - 2.9 7.8 9.3 7.9 6.4 4.0 2.6 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Vps55 PF04133.9 CBZ27762.1 - 1.8e-28 98.7 2.0 2e-28 98.5 1.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2372 PF10178.4 CBZ27763.1 - 0.0024 17.9 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) DFP PF04127.10 CBZ27764.1 - 1.8e-20 73.3 0.0 3.1e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein DNA_repr_REX1B PF14966.1 CBZ27765.1 - 0.0076 16.5 2.9 0.12 12.7 0.4 2.3 2 0 0 2 2 2 1 DNA repair REX1-B Baculo_p24 PF05073.7 CBZ27765.1 - 0.015 14.8 0.1 0.023 14.2 0.1 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein DASH_Dad3 PF08656.5 CBZ27765.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad3 TPR_12 PF13424.1 CBZ27766.1 - 1.4e-12 47.3 22.7 2.4e-06 27.3 0.6 3.6 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ27766.1 - 0.00016 21.2 4.4 0.42 10.5 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ27766.1 - 0.0085 15.8 0.3 0.0085 15.8 0.2 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat Tcf25 PF04910.9 CBZ27766.1 - 0.025 13.5 0.5 0.04 12.8 0.3 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 TPR_11 PF13414.1 CBZ27766.1 - 0.063 12.9 18.1 0.58 9.8 0.3 4.5 2 2 1 3 3 3 0 TPR repeat TPR_1 PF00515.23 CBZ27766.1 - 0.065 12.8 0.0 0.065 12.8 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ27766.1 - 0.23 11.4 0.1 0.23 11.4 0.0 6.7 6 1 1 7 7 7 0 Tetratricopeptide repeat Apc5 PF12862.2 CBZ27766.1 - 2.3 8.1 11.6 0.86 9.4 0.2 3.5 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_14 PF13428.1 CBZ27766.1 - 3.4 8.5 29.8 2.4 9.0 0.0 6.8 6 1 1 7 7 7 0 Tetratricopeptide repeat RRM_1 PF00076.17 CBZ27767.1 - 0.042 13.4 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.18 CBZ27769.1 - 3.5e-79 265.9 0.1 3.5e-79 265.9 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF342 PF03961.8 CBZ27769.1 - 0.056 11.8 9.4 0.004 15.6 3.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) ResIII PF04851.10 CBZ27769.1 - 0.07 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 CBZ27769.1 - 0.27 11.1 8.9 2.5 8.0 0.0 4.1 3 2 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 CBZ27769.1 - 1.7 8.9 6.9 3.2 8.0 1.1 2.6 2 0 0 2 2 2 0 AAA domain Acylphosphatase PF00708.13 CBZ27770.1 - 1.2e-23 82.9 0.0 1.8e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Acylphosphatase Kinesin PF00225.18 CBZ27771.1 - 4.7e-101 337.8 0.0 7.2e-101 337.2 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Fib_alpha PF08702.5 CBZ27771.1 - 0.06 13.4 15.8 0.014 15.4 3.1 3.8 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family AAA_22 PF13401.1 CBZ27771.1 - 0.32 11.1 3.4 0.34 11.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain SlyX PF04102.7 CBZ27771.1 - 1.9 8.9 20.1 0.35 11.2 0.2 6.4 6 1 0 6 6 6 0 SlyX Pkinase PF00069.20 CBZ27773.1 - 8.7e-57 192.2 0.0 3.5e-42 144.3 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27773.1 - 2.8e-32 111.7 0.0 1.4e-23 83.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ27773.1 - 0.00046 19.2 0.0 0.033 13.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBZ27773.1 - 0.0075 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ27773.1 - 0.0086 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBZ27773.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Iso_dh PF00180.15 CBZ27773.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase Choline_kinase PF01633.15 CBZ27773.1 - 0.22 11.0 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase HpcH_HpaI PF03328.9 CBZ27775.1 - 3.2e-54 183.1 0.0 3.8e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DHQS PF01959.11 CBZ27775.1 - 0.01 14.5 0.0 0.015 13.9 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) rRNA_methylase PF06962.7 CBZ27775.1 - 0.058 13.1 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Putative rRNA methylase AAA_16 PF13191.1 CBZ27776.1 - 0.00016 21.7 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 CBZ27776.1 - 0.0032 16.2 0.1 0.0048 15.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 CBZ27776.1 - 0.0068 15.5 0.0 0.24 10.4 0.0 2.3 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 CBZ27776.1 - 0.011 16.5 0.1 0.037 14.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 CBZ27776.1 - 0.013 14.9 0.5 0.1 12.0 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF1456 PF07308.8 CBZ27776.1 - 0.021 14.8 1.2 0.21 11.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) AAA_30 PF13604.1 CBZ27776.1 - 0.033 13.7 0.0 0.078 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBZ27776.1 - 0.049 13.9 0.1 0.14 12.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain NIF PF03031.13 CBZ27777.1 - 7e-47 159.0 0.1 1.1e-46 158.4 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SNF2_N PF00176.18 CBZ27779.1 - 2.4e-46 157.8 0.1 3.7e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ27779.1 - 4.5e-11 42.4 0.0 1.1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.24 CBZ27779.1 - 2.7e-06 26.9 14.3 0.0019 17.8 2.7 2.5 2 0 0 2 2 2 2 PHD-finger HDA2-3 PF11496.3 CBZ27779.1 - 3.1e-05 22.9 0.0 7.4e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CBZ27779.1 - 9.5e-05 21.9 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CBZ27779.1 - 0.0015 18.3 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-PHD-like PF15446.1 CBZ27779.1 - 0.0073 15.6 7.9 0.056 12.7 0.7 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 CBZ27779.1 - 5.3 6.8 17.5 3.3 7.5 3.8 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 SpoIIE PF07228.7 CBZ27780.1 - 6.4e-16 58.6 0.2 7.6e-15 55.1 0.1 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CBZ27780.1 - 7.7e-06 25.4 0.0 1.8e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CBZ27780.1 - 7.8e-05 22.1 0.1 0.0014 18.0 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C Rieske_2 PF13806.1 CBZ27781.1 - 4.1e-07 29.6 0.0 7.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.21 CBZ27781.1 - 8.8e-07 28.4 0.4 1.9e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NAD_binding_1 PF00175.16 CBZ27781.1 - 5.2e-05 23.7 0.0 0.013 16.1 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain GTP_EFTU PF00009.22 CBZ27782.1 - 2.4e-47 160.8 0.0 3.9e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CBZ27782.1 - 1.5e-14 53.5 0.0 4.6e-14 52.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 CBZ27782.1 - 2e-08 33.8 0.0 4.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 CBZ27782.1 - 1.2e-06 28.5 0.0 2.8e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CBZ27782.1 - 0.00064 19.5 0.1 0.0027 17.4 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II Miro PF08477.8 CBZ27782.1 - 0.043 14.2 0.0 0.095 13.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 CBZ27782.1 - 0.068 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.17 CBZ27782.1 - 0.071 12.5 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Ras family SRPRB PF09439.5 CBZ27782.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit mRNA_triPase PF02940.10 CBZ27784.1 - 7.6e-33 114.0 0.0 1e-32 113.6 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain TPR_11 PF13414.1 CBZ27785.1 - 1.8e-19 69.0 17.9 5.5e-07 29.1 2.2 4.8 1 1 5 6 6 6 6 TPR repeat TPR_2 PF07719.12 CBZ27785.1 - 8.5e-16 56.5 24.9 0.007 16.2 0.1 7.1 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ27785.1 - 1.2e-11 43.7 18.7 0.00085 18.8 0.1 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ27785.1 - 3.7e-11 43.3 28.3 0.0038 17.8 0.7 4.6 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ27785.1 - 6.5e-08 32.3 16.7 0.00026 20.8 0.3 4.6 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ27785.1 - 8.9e-08 32.1 11.6 0.062 13.9 0.1 5.8 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ27785.1 - 1.1e-05 24.7 17.3 0.017 14.8 0.0 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ27785.1 - 8e-05 22.9 9.2 0.41 11.0 0.1 4.6 2 2 2 4 4 4 3 Tetratricopeptide repeat zf-CCHC PF00098.18 CBZ27785.1 - 0.0048 16.7 0.6 0.0088 15.9 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle Apc3 PF12895.2 CBZ27785.1 - 0.0049 16.9 16.4 0.22 11.6 0.8 4.4 3 2 3 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBZ27785.1 - 0.023 15.1 10.2 7 7.3 0.0 5.2 5 1 0 5 5 4 0 Tetratricopeptide repeat FAT PF02259.18 CBZ27785.1 - 0.027 13.4 1.3 0.52 9.2 0.1 2.3 1 1 1 2 2 2 0 FAT domain TPR_17 PF13431.1 CBZ27785.1 - 0.044 13.9 8.2 2.7 8.4 0.0 5.6 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ27785.1 - 0.094 12.6 3.4 11 6.0 0.0 3.5 3 1 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 CBZ27785.1 - 0.17 11.7 8.8 1.4 8.7 0.3 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ27785.1 - 0.57 10.2 8.5 1.4 8.9 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 CBZ27785.1 - 2.2 8.1 6.3 12 5.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat KBP_C PF12309.3 CBZ27786.1 - 1.7e-90 303.6 0.1 1.5e-89 300.6 0.0 2.2 2 0 0 2 2 2 1 KIF-1 binding protein C terminal TPR_7 PF13176.1 CBZ27786.1 - 0.055 13.2 3.6 2.8 7.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat NRN1 PF15056.1 CBZ27786.1 - 0.085 12.8 0.4 0.23 11.4 0.3 1.8 1 0 0 1 1 1 0 Neuritin protein family eIF3_subunit PF08597.5 CBZ27787.1 - 4.6e-05 23.0 16.4 0.00027 20.5 11.4 1.9 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit TTSSLRR PF12468.3 CBZ27787.1 - 1.5 8.3 7.0 5 6.7 4.9 1.8 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein CoA_binding PF02629.14 CBZ27788.1 - 1.4e-26 92.7 2.4 1.4e-26 92.7 1.7 2.1 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 CBZ27788.1 - 3.1e-23 82.0 0.7 4.9e-23 81.4 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 CBZ27788.1 - 6.5e-09 35.5 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBZ27788.1 - 0.00038 20.6 0.1 0.00078 19.5 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 CBZ27789.1 - 1.4e-26 92.7 2.4 1.4e-26 92.7 1.7 2.1 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 CBZ27789.1 - 3.1e-23 82.0 0.7 4.9e-23 81.4 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 CBZ27789.1 - 6.5e-09 35.5 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CBZ27789.1 - 0.00038 20.6 0.1 0.00078 19.5 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain BRO1 PF03097.13 CBZ27790.1 - 1.6e-25 89.6 0.0 2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain KIX PF02172.11 CBZ27790.1 - 0.066 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 KIX domain Med25_SD1 PF11235.3 CBZ27791.1 - 0.04 14.2 4.8 0.066 13.5 3.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 EMP24_GP25L PF01105.19 CBZ27791.1 - 0.09 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Fzo_mitofusin PF04799.8 CBZ27791.1 - 0.19 11.1 1.2 0.32 10.3 0.8 1.4 1 0 0 1 1 1 0 fzo-like conserved region Rad60-SLD PF11976.3 CBZ27792.1 - 9.8e-05 21.9 0.2 0.00016 21.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CBZ27792.1 - 0.00055 19.2 0.1 0.00096 18.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family MobB PF03205.9 CBZ27793.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Sec1 PF00995.18 CBZ27794.1 - 5.5e-80 269.6 0.0 6.8e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ATP-synt_F PF01990.12 CBZ27794.1 - 0.13 12.7 0.1 3.5 8.0 0.0 3.0 3 0 0 3 3 3 0 ATP synthase (F/14-kDa) subunit DnaJ PF00226.26 CBZ27795.1 - 1.3e-23 82.5 1.8 2.8e-23 81.4 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 CBZ27795.1 - 1.8e-09 37.4 4.9 3.6e-09 36.4 3.4 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBZ27795.1 - 4.4e-08 33.0 3.1 8e-08 32.2 2.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CBZ27795.1 - 5.3e-05 23.2 0.3 0.00017 21.6 0.1 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 CBZ27795.1 - 0.017 14.9 0.3 0.017 14.9 0.2 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 CBZ27795.1 - 0.039 14.2 1.3 0.13 12.6 0.9 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger CGGC PF08821.6 CBZ27795.1 - 0.11 12.5 0.5 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 CGGC domain Evr1_Alr PF04777.8 CBZ27795.1 - 0.17 11.7 2.1 6.5 6.7 0.1 2.5 2 0 0 2 2 2 0 Erv1 / Alr family zf-C2H2 PF00096.21 CBZ27795.1 - 0.32 11.4 4.3 0.15 12.4 1.2 1.9 2 0 0 2 2 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CBZ27795.1 - 0.67 9.9 3.2 0.24 11.3 0.3 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger Caldesmon PF02029.10 CBZ27795.1 - 1.2 7.4 26.3 0.048 12.0 14.3 1.4 2 0 0 2 2 2 0 Caldesmon CBP4 PF07960.6 CBZ27795.1 - 7.8 6.1 15.0 5.9 6.5 7.7 2.4 2 0 0 2 2 2 0 CBP4 ParcG PF10274.4 CBZ27796.1 - 4.8e-78 261.2 0.0 5.7e-78 261.0 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Totivirus_coat PF05518.6 CBZ27796.1 - 2.3 5.9 4.3 2.7 5.7 3.0 1.0 1 0 0 1 1 1 0 Totivirus coat protein PCI PF01399.22 CBZ27797.1 - 2.4e-06 27.7 0.1 8.5e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_1 PF00515.23 CBZ27797.1 - 0.001 18.6 2.4 0.075 12.6 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ27797.1 - 0.0058 16.5 11.7 1 9.3 0.0 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ27797.1 - 0.0074 15.9 6.5 0.38 10.4 0.9 4.0 3 1 1 4 4 4 2 TPR repeat TPR_9 PF13371.1 CBZ27797.1 - 0.041 13.7 4.9 1.3 8.9 0.6 3.6 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ27797.1 - 0.085 12.8 9.6 1.2 9.1 0.1 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ27797.1 - 0.09 13.4 14.9 4 8.3 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ27797.1 - 0.16 12.6 12.5 25 5.6 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ27797.1 - 3.9 7.5 8.1 13 5.8 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4160 PF13711.1 CBZ27798.1 - 0.043 13.6 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) Cluap1 PF10234.4 CBZ27798.1 - 0.067 12.3 7.9 0.12 11.5 5.5 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF1664 PF07889.7 CBZ27798.1 - 0.87 9.3 7.6 0.86 9.4 1.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4446 PF14584.1 CBZ27798.1 - 8.5 6.1 8.6 4.3 7.1 2.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Pex2_Pex12 PF04757.9 CBZ27799.1 - 5.5e-30 104.4 12.2 7.1e-30 104.1 8.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 CBZ27799.1 - 0.017 14.7 12.1 0.027 14.1 8.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ27799.1 - 0.024 14.6 11.0 0.047 13.7 7.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ27799.1 - 0.041 13.7 9.0 0.078 12.8 6.3 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Sp100 PF03172.8 CBZ27799.1 - 0.069 13.1 0.4 5.3 7.0 0.1 2.3 1 1 1 2 2 2 0 Sp100 domain zf-RING_5 PF14634.1 CBZ27799.1 - 0.096 12.4 11.9 0.15 11.7 8.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ27799.1 - 2.2 8.0 13.3 3.3 7.4 9.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ27799.1 - 4.4 7.2 12.0 10 6.0 8.3 1.6 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.24 CBZ27800.1 - 1.2e-05 24.8 7.9 1.2e-05 24.8 5.4 3.1 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 CBZ27800.1 - 0.03 13.6 0.8 0.03 13.6 0.5 2.8 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PepSY_TM_2 PF13703.1 CBZ27801.1 - 0.059 13.5 0.8 11 6.2 0.1 2.9 3 0 0 3 3 3 0 PepSY-associated TM helix TMEM190 PF15431.1 CBZ27803.1 - 0.06 13.2 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 190 zf-DHHC PF01529.15 CBZ27805.1 - 5.6e-38 130.0 0.5 2.6e-37 127.8 0.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.12 CBZ27805.1 - 0.022 14.2 0.2 0.022 14.2 0.1 2.2 2 0 0 2 2 2 0 Yip1 domain 4HBT_3 PF13622.1 CBZ27805.1 - 0.046 13.4 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily YjgP_YjgQ PF03739.9 CBZ27805.1 - 0.048 12.3 1.3 2.9 6.5 0.4 2.3 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family DUF1212 PF06738.7 CBZ27805.1 - 0.37 10.2 6.1 5.8 6.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Neur_chan_memb PF02932.11 CBZ27805.1 - 1 9.1 5.8 2.5 7.9 4.0 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4064 PF13273.1 CBZ27805.1 - 3.8 7.6 10.3 21 5.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) MFS_Mycoplasma PF07672.8 CBZ27805.1 - 8.9 5.3 8.7 11 5.0 0.7 2.4 2 1 0 2 2 2 0 Mycoplasma MFS transporter Pex2_Pex12 PF04757.9 CBZ27806.1 - 9.7e-15 54.6 0.1 2.8e-07 30.2 0.0 2.1 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CBZ27806.1 - 3.9e-09 36.3 9.1 6.4e-09 35.6 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ27806.1 - 4e-09 36.1 8.3 6.6e-09 35.4 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CBZ27806.1 - 4.4e-09 35.9 6.7 7.7e-09 35.1 4.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ27806.1 - 6.6e-09 35.3 7.0 1e-08 34.7 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ27806.1 - 7.4e-07 28.7 8.0 1.2e-06 28.0 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ27806.1 - 7.5e-07 28.9 7.9 1.4e-06 28.0 5.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBZ27806.1 - 1.5e-05 24.6 3.2 2.6e-05 23.9 2.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBZ27806.1 - 3.4e-05 23.8 3.5 6.1e-05 23.0 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger TerY-C PF15616.1 CBZ27806.1 - 0.00027 20.8 1.5 0.00044 20.1 1.0 1.2 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_UBOX PF13445.1 CBZ27806.1 - 0.00057 19.5 1.9 0.00085 18.9 0.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 CBZ27806.1 - 0.031 14.0 4.0 0.14 11.9 2.1 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Di19 PF05605.7 CBZ27806.1 - 0.066 13.3 1.0 0.31 11.2 0.1 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Rtf2 PF04641.7 CBZ27806.1 - 0.073 12.2 0.2 0.13 11.4 0.1 1.4 1 1 0 1 1 1 0 Rtf2 RING-finger zf-Nse PF11789.3 CBZ27806.1 - 0.097 12.2 2.7 0.22 11.0 1.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 CBZ27806.1 - 0.63 9.6 8.5 1.4 8.5 5.9 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.2 CBZ27806.1 - 1.3 8.9 5.9 11 5.9 4.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon FYVE PF01363.16 CBZ27806.1 - 1.5 8.7 6.5 4.3 7.3 4.5 1.8 1 1 0 1 1 1 0 FYVE zinc finger FANCL_C PF11793.3 CBZ27806.1 - 2 8.4 7.3 14 5.6 5.1 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 CBZ27806.1 - 2.1 7.9 7.2 14 5.2 5.0 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 IBR PF01485.16 CBZ27806.1 - 2.3 8.1 8.6 10 6.0 5.9 2.1 1 1 0 1 1 1 0 IBR domain zf-C2HC5 PF06221.8 CBZ27806.1 - 3.3 7.5 6.4 0.82 9.4 1.3 2.1 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type LRR_4 PF12799.2 CBZ27807.1 - 1.4e-09 37.3 3.9 2.1e-05 24.0 0.7 3.1 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ27807.1 - 1.7e-07 30.8 5.9 1.9e-06 27.5 1.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat EF-hand_7 PF13499.1 CBZ27807.1 - 6.6e-06 26.1 0.3 2.8e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ27807.1 - 0.00027 20.0 0.1 0.013 14.7 0.0 2.9 2 0 0 2 2 2 1 EF hand LRR_7 PF13504.1 CBZ27807.1 - 0.001 18.9 4.6 0.58 10.5 0.2 4.0 3 0 0 3 3 3 1 Leucine rich repeat EF-hand_8 PF13833.1 CBZ27807.1 - 0.0019 17.7 0.2 0.27 10.8 0.0 2.9 1 1 1 2 2 2 1 EF-hand domain pair LRR_1 PF00560.28 CBZ27807.1 - 0.002 17.9 4.6 0.66 10.2 0.5 3.6 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.1 CBZ27807.1 - 0.009 15.9 2.0 0.78 9.9 0.1 3.1 2 1 1 3 3 3 1 Leucine Rich repeat EF-hand_6 PF13405.1 CBZ27807.1 - 0.016 15.0 0.0 0.091 12.6 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain UPF0240 PF06784.6 CBZ27808.1 - 0.06 13.0 0.2 0.25 11.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) DUF4352 PF11611.3 CBZ27808.1 - 0.082 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) SPC12 PF06645.8 CBZ27809.1 - 8e-06 25.5 0.8 1.4e-05 24.7 0.5 1.4 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) COX14 PF14880.1 CBZ27809.1 - 0.041 13.4 0.4 0.13 11.8 0.3 1.8 1 1 0 1 1 1 0 Cytochrome oxidase c assembly VPS9 PF02204.13 CBZ27810.1 - 1.9e-13 50.2 0.0 3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.15 CBZ27810.1 - 1.6e-08 33.7 20.2 1.3e-05 24.6 0.9 6.0 6 0 0 6 6 6 2 MORN repeat Cellulase-like PF12876.2 CBZ27810.1 - 0.016 15.6 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 Sugar-binding cellulase-like Pkinase PF00069.20 CBZ27811.1 - 6.3e-69 232.0 0.0 9.5e-69 231.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27811.1 - 1.3e-38 132.5 0.0 1.8e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ27811.1 - 1.2e-06 27.6 0.0 2.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ27811.1 - 0.0086 15.8 0.0 0.26 11.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ27811.1 - 0.014 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_4 PF07721.9 CBZ27812.1 - 1.9 9.1 5.5 0.81 10.2 1.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ADK PF00406.17 CBZ27814.1 - 1.6e-34 118.9 0.0 1.9e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CBZ27814.1 - 1.4e-18 66.2 2.8 2.2e-18 65.6 2.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CBZ27814.1 - 1.9e-05 25.4 0.0 2.6e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain A2L_zn_ribbon PF08792.5 CBZ27814.1 - 0.002 17.5 0.5 0.46 10.0 0.0 2.4 2 0 0 2 2 2 2 A2L zinc ribbon domain AAA_18 PF13238.1 CBZ27814.1 - 0.034 14.4 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBZ27814.1 - 0.076 12.8 0.1 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain GSP_synth PF03738.9 CBZ27816.1 - 5.7e-24 84.1 0.0 1.1e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.11 CBZ27816.1 - 8e-20 70.7 0.0 1.5e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 CHAP domain CP_ATPgrasp_2 PF14403.1 CBZ27816.1 - 0.16 10.5 0.0 0.27 9.8 0.0 1.3 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 Arv1 PF04161.8 CBZ27817.1 - 8.4e-20 71.5 4.9 1.5e-19 70.7 3.4 1.6 1 1 0 1 1 1 1 Arv1-like family DUF2404 PF10296.4 CBZ27817.1 - 0.12 12.4 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) DUF360 PF04020.8 CBZ27817.1 - 1.3 9.3 12.0 0.94 9.8 2.1 2.5 1 1 1 2 2 2 0 Membrane protein of unknown function Histone PF00125.19 CBZ27822.1 - 1.1e-13 51.1 0.7 1.3e-13 50.8 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ27822.1 - 6.6e-05 22.8 0.8 7.1e-05 22.7 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CBZ27822.1 - 0.0003 20.6 0.2 0.00048 20.0 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CBZ27822.1 - 0.00065 19.3 0.0 0.00083 19.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CBZ27822.1 - 0.0016 18.1 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 CBZ27822.1 - 0.086 12.7 1.0 0.17 11.7 0.2 2.0 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit FbpA PF05833.6 CBZ27822.1 - 0.086 11.3 0.0 0.1 11.1 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Galactosyl_T PF01762.16 CBZ27823.1 - 0.00039 20.0 0.2 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 Galactosyltransferase LSM PF01423.17 CBZ27824.1 - 1.7e-11 43.5 0.2 2.7e-11 42.8 0.1 1.4 1 1 0 1 1 1 1 LSM domain Brix PF04427.13 CBZ27825.1 - 5.6e-37 127.2 0.0 1.8e-36 125.5 0.0 1.7 2 0 0 2 2 2 1 Brix domain Spc7 PF08317.6 CBZ27825.1 - 0.072 11.7 0.2 5.5 5.5 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Glyoxalase_4 PF13669.1 CBZ27826.1 - 1.6e-16 60.2 0.0 1.9e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CBZ27826.1 - 5.6e-05 23.1 0.0 6.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.2 CBZ27826.1 - 5.7e-05 23.6 0.0 9.6e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 CBZ27826.1 - 0.0023 17.9 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GDC-P PF02347.11 CBZ27827.1 - 1.1e-172 574.6 0.1 1.5e-156 521.3 0.0 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 CBZ27827.1 - 0.00073 18.7 0.2 0.0025 17.0 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 CBZ27827.1 - 0.06 11.6 0.0 0.67 8.1 0.0 2.1 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Det1 PF09737.4 CBZ27827.1 - 0.097 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Pkinase PF00069.20 CBZ27828.1 - 1.4e-55 188.3 0.0 1.5e-55 188.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27828.1 - 2e-23 82.8 0.0 2.1e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ27828.1 - 0.00014 20.9 0.0 0.00038 19.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Rhomboid PF01694.17 CBZ27834.1 - 0.0033 17.4 0.8 0.01 15.8 0.1 1.9 2 0 0 2 2 2 1 Rhomboid family Rhomboid PF01694.17 CBZ27835.1 - 0.0033 17.4 0.8 0.01 15.8 0.1 1.9 2 0 0 2 2 2 1 Rhomboid family Pribosyltran PF00156.22 CBZ27836.1 - 1.7e-15 56.8 0.0 2.6e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBZ27836.1 - 3.7e-05 23.0 0.0 5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 CBZ27836.1 - 0.016 14.5 0.0 0.04 13.2 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl transferase Racemase_4 PF13615.1 CBZ27837.1 - 1.8e-21 76.2 0.2 4.2e-21 75.1 0.1 1.7 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 CBZ27837.1 - 2.5e-13 49.6 0.0 4.6e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor NIF PF03031.13 CBZ27838.1 - 2.5e-48 163.7 0.4 4.4e-48 162.9 0.3 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_L30 PF00327.15 CBZ27839.1 - 1.7e-18 65.9 1.7 3.4e-18 64.9 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CBZ27839.1 - 4.3e-16 58.6 14.2 8.6e-16 57.7 9.8 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 CBZ27840.1 - 2.2e-18 65.5 1.7 4.3e-18 64.6 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CBZ27840.1 - 5.7e-16 58.3 14.2 1.1e-15 57.3 9.8 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DUF1453 PF07301.6 CBZ27841.1 - 0.23 11.3 4.6 2.8 7.8 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1453) Sm_multidrug_ex PF06695.6 CBZ27841.1 - 0.52 10.4 4.3 0.62 10.2 0.4 2.2 1 1 2 3 3 3 0 Putative small multi-drug export protein Nfu_N PF08712.6 CBZ27842.1 - 3.9e-23 80.8 0.0 6.6e-23 80.1 0.0 1.4 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 CBZ27842.1 - 2.6e-21 75.1 0.0 2.6e-21 75.1 0.0 2.3 3 0 0 3 3 3 1 NifU-like domain eRF1_1 PF03463.10 CBZ27843.1 - 3.1e-32 110.9 0.2 8.1e-32 109.5 0.0 1.7 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.10 CBZ27843.1 - 8.6e-20 71.4 0.1 1.4e-19 70.6 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CBZ27843.1 - 2.1e-14 53.7 0.0 7.2e-14 52.0 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 DUF334 PF03904.8 CBZ27843.1 - 0.0046 16.3 0.3 0.0072 15.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF334) VGCC_alpha2 PF08473.6 CBZ27843.1 - 0.11 12.2 0.1 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd SIR2 PF02146.12 CBZ27844.1 - 7.2e-57 191.9 0.0 9.9e-57 191.5 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zinc_ribbon_4 PF13717.1 CBZ27844.1 - 0.019 14.6 1.6 0.059 13.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBZ27844.1 - 0.033 13.7 1.6 0.08 12.5 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DUF2305 PF10230.4 CBZ27845.1 - 4.9e-60 203.1 0.0 5.7e-60 202.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 CBZ27845.1 - 5.9e-13 49.2 0.3 7.7e-13 48.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ27845.1 - 4.6e-11 42.6 0.0 6e-11 42.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBZ27845.1 - 0.0023 17.7 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 CBZ27845.1 - 0.0053 16.3 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 CBZ27845.1 - 0.019 15.2 0.1 0.032 14.4 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain Nodulin-like PF06813.8 CBZ27845.1 - 0.019 14.1 0.1 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 Nodulin-like DUF1057 PF06342.7 CBZ27845.1 - 0.021 13.6 0.0 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_1 PF00561.15 CBZ27845.1 - 0.043 13.3 0.1 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold IF4E PF01652.13 CBZ27847.1 - 8.5e-12 44.9 0.0 1.1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ANTAR PF03861.9 CBZ27848.1 - 0.013 15.0 0.6 0.033 13.7 0.4 1.8 1 0 0 1 1 1 0 ANTAR domain DUF440 PF04269.7 CBZ27848.1 - 0.2 11.6 0.3 0.44 10.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF440 MMR_HSR1 PF01926.18 CBZ27850.1 - 2.9e-42 143.2 0.1 7.6e-20 71.0 0.0 2.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CBZ27850.1 - 1.1e-26 93.4 0.6 4.3e-13 49.1 0.0 3.7 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBZ27850.1 - 2.6e-20 72.3 0.1 5e-09 35.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Miro PF08477.8 CBZ27850.1 - 1.2e-18 67.7 0.0 5e-08 33.4 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 CBZ27850.1 - 6.6e-17 61.8 0.1 0.0009 19.0 0.0 4.3 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.11 CBZ27850.1 - 4.8e-15 55.2 0.0 8.3e-07 28.3 0.0 2.6 2 0 0 2 2 2 2 AIG1 family KH_dom-like PF14714.1 CBZ27850.1 - 1.7e-14 53.5 0.3 3.4e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SRPRB PF09439.5 CBZ27850.1 - 4.1e-12 45.7 0.0 1.8e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.17 CBZ27850.1 - 9.7e-11 41.3 0.1 1.6e-06 27.6 0.1 2.7 2 1 0 2 2 2 2 Ras family MobB PF03205.9 CBZ27850.1 - 1.9e-06 27.6 0.0 0.011 15.3 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CBZ27850.1 - 7.5e-06 25.4 0.0 0.4 10.1 0.0 3.7 3 1 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CBZ27850.1 - 9.6e-06 24.8 0.0 0.01 14.8 0.0 2.4 2 0 0 2 2 2 2 Septin ABC_tran PF00005.22 CBZ27850.1 - 1.3e-05 25.4 0.0 0.23 11.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 CBZ27850.1 - 1.4e-05 24.3 0.0 0.12 11.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 CBZ27850.1 - 3.9e-05 23.9 0.0 0.064 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 CBZ27850.1 - 9.8e-05 21.8 1.2 0.5 9.7 0.2 4.0 3 1 1 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 CBZ27850.1 - 0.00013 21.2 0.8 0.088 12.0 0.1 3.3 2 2 0 2 2 2 1 ADP-ribosylation factor family GBP PF02263.14 CBZ27850.1 - 0.00019 20.5 0.0 0.4 9.6 0.0 2.4 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain AAA_17 PF13207.1 CBZ27850.1 - 0.00082 20.1 1.2 2.6 8.8 0.1 3.5 3 2 0 3 3 2 2 AAA domain IIGP PF05049.8 CBZ27850.1 - 0.00095 18.0 0.0 0.16 10.7 0.0 2.5 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Arch_ATPase PF01637.13 CBZ27850.1 - 0.0012 18.5 0.0 0.21 11.2 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase ATP_bind_1 PF03029.12 CBZ27850.1 - 0.0013 18.3 2.2 7.5 6.0 0.1 3.8 2 2 2 4 4 4 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CBZ27850.1 - 0.0022 17.4 0.0 1.4 8.2 0.0 2.7 2 1 0 2 2 2 2 AAA-like domain T2SE PF00437.15 CBZ27850.1 - 0.0075 15.2 0.0 0.025 13.4 0.0 2.0 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.1 CBZ27850.1 - 0.014 14.9 0.0 3.8 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 CBZ27850.1 - 0.015 15.4 0.0 2.3 8.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 CBZ27850.1 - 0.033 13.6 0.0 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 CBZ27850.1 - 0.078 13.2 0.0 23 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 CBZ27850.1 - 0.16 11.8 0.0 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ank_3 PF13606.1 CBZ27851.1 - 0.0072 16.4 0.0 14 6.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 CBZ27851.1 - 0.058 13.7 0.4 2.8 8.3 0.3 2.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) DUF1759 PF03564.10 CBZ27851.1 - 0.09 12.5 0.0 0.27 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) NUDIX_2 PF13869.1 CBZ27852.1 - 1.3e-41 141.9 0.0 1.3e-40 138.6 0.0 2.4 1 1 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.23 CBZ27852.1 - 0.0073 15.9 0.2 0.023 14.3 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain Peptidase_M1 PF01433.15 CBZ27853.1 - 4.4e-111 371.7 0.0 8.5e-111 370.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CBZ27853.1 - 2e-53 181.7 0.0 3.2e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CBZ27853.1 - 9.5e-19 67.7 0.9 3.1e-18 66.0 0.6 1.9 1 0 0 1 1 1 1 Peptidase MA superfamily DUF45 PF01863.12 CBZ27853.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF45 6PF2K PF01591.13 CBZ27854.1 - 1.9e-32 112.1 0.0 2.8e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank_2 PF12796.2 CBZ27854.1 - 2.2e-22 79.1 0.0 7.1e-12 45.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) His_Phos_1 PF00300.17 CBZ27854.1 - 1.4e-15 57.7 0.0 3.6e-15 56.4 0.0 1.7 2 0 0 2 2 1 1 Histidine phosphatase superfamily (branch 1) Ank_5 PF13857.1 CBZ27854.1 - 1.4e-13 50.5 0.1 3.7e-13 49.2 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CBZ27854.1 - 5e-12 44.9 0.1 5.3e-08 32.2 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CBZ27854.1 - 1.8e-11 44.2 0.0 1.5e-07 31.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ27854.1 - 1e-07 31.4 0.1 2.9e-06 27.0 0.0 3.3 4 0 0 4 4 2 1 Ankyrin repeat AAA_33 PF13671.1 CBZ27854.1 - 2.5e-06 27.4 0.2 4.9e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CBZ27854.1 - 0.00017 20.9 0.1 0.00034 19.9 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CBZ27854.1 - 0.006 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 CBZ27854.1 - 0.013 15.2 0.2 0.079 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ27854.1 - 0.028 14.5 0.0 0.083 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBZ27854.1 - 0.061 14.1 0.0 0.16 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain THF_DHG_CYH_C PF02882.14 CBZ27855.1 - 1e-61 206.7 0.4 1.7e-61 206.0 0.3 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CBZ27855.1 - 4e-39 133.2 0.6 5.4e-39 132.8 0.4 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Cyclin_N PF00134.18 CBZ27856.1 - 8.7e-14 51.1 0.5 3.1e-13 49.4 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF2637 PF10935.3 CBZ27856.1 - 0.031 14.2 0.5 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2637) Cyclin_C PF02984.14 CBZ27856.1 - 0.051 13.5 2.0 0.13 12.2 0.4 2.3 1 1 1 2 2 2 0 Cyclin, C-terminal domain IU_nuc_hydro PF01156.14 CBZ27857.1 - 7.8e-29 100.8 2.2 1.8e-26 93.0 0.8 2.0 1 1 1 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase MIG-14_Wnt-bd PF06664.7 CBZ27857.1 - 0.009 14.8 0.1 0.011 14.5 0.1 1.2 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion FGGY_C PF02782.11 CBZ27857.1 - 0.02 14.5 0.5 0.09 12.3 0.2 2.0 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Vps52 PF04129.7 CBZ27858.1 - 5.8e-51 173.5 0.4 1e-17 63.8 0.0 3.6 3 1 0 3 3 3 3 Vps52 / Sac2 family DASH_Duo1 PF08651.5 CBZ27858.1 - 0.013 15.0 0.3 1.7 8.2 0.2 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 Sec3_C PF09763.4 CBZ27858.1 - 0.096 10.7 1.9 1.5 6.8 0.1 2.7 3 0 0 3 3 3 0 Exocyst complex component Sec3 TPR_11 PF13414.1 CBZ27860.1 - 1.8e-35 120.4 19.5 0.00039 20.0 0.0 9.9 6 3 2 10 10 10 8 TPR repeat TPR_2 PF07719.12 CBZ27860.1 - 2.7e-30 101.8 32.4 0.00088 19.0 0.0 15.0 16 1 0 16 16 15 6 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ27860.1 - 4.7e-22 76.6 21.5 0.00016 21.1 0.0 11.3 14 0 0 14 14 12 5 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ27860.1 - 4.9e-21 74.4 37.9 1.8e-05 24.5 1.9 11.4 8 2 4 12 12 12 8 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ27860.1 - 1.4e-19 68.3 10.7 0.0007 19.2 0.0 11.2 15 0 0 15 15 13 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ27860.1 - 2e-15 56.9 47.6 0.0094 16.6 2.7 11.2 9 2 4 13 13 13 6 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ27860.1 - 1.2e-13 50.6 45.8 0.074 12.9 0.3 11.2 5 3 6 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ27860.1 - 1.3e-08 34.7 46.7 0.45 11.2 0.0 12.1 10 2 3 13 13 12 4 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ27860.1 - 2.3e-07 30.4 12.9 4 7.8 0.0 9.3 10 0 0 10 10 10 1 Tetratricopeptide repeat NARP1 PF12569.3 CBZ27860.1 - 1.8e-06 27.0 0.1 0.83 8.3 0.0 4.3 4 0 0 4 4 4 2 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 CBZ27860.1 - 6.7e-06 26.3 27.3 0.037 14.3 0.0 8.1 9 1 1 10 10 8 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ27860.1 - 3e-05 24.0 16.3 1.1 9.4 0.8 7.0 3 3 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CBZ27860.1 - 0.0004 19.5 4.1 14 4.6 0.2 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Apc5 PF12862.2 CBZ27860.1 - 0.0044 16.8 6.9 9.4 6.1 0.0 6.4 4 2 3 7 7 7 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.1 CBZ27860.1 - 0.023 15.1 27.5 37 5.0 0.0 10.6 13 0 0 13 13 10 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBZ27860.1 - 0.068 12.4 3.0 0.96 8.7 0.0 4.3 5 0 0 5 5 5 0 SHNi-TPR Fis1_TPR_C PF14853.1 CBZ27860.1 - 0.072 12.9 8.2 1.3 8.9 0.0 5.2 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Ist1 PF03398.9 CBZ27861.1 - 8.2e-60 200.9 0.1 1e-59 200.6 0.1 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway PAP_assoc PF03828.14 CBZ27862.1 - 1.9e-15 56.5 0.1 4e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBZ27862.1 - 6e-06 26.4 0.0 1.6e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyltransferase domain 2OG-FeII_Oxy_2 PF13532.1 CBZ27863.1 - 2.3e-13 50.4 0.0 3.9e-13 49.6 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBZ27863.1 - 2.2e-07 31.0 0.0 4.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nfu_N PF08712.6 CBZ27863.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal Pan_kinase PF03309.9 CBZ27863.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Type III pantothenate kinase zf-trcl PF13451.1 CBZ27864.1 - 0.004 16.7 0.7 0.004 16.7 0.5 2.5 2 0 0 2 2 2 1 Probable zinc-binding domain DUF1091 PF06477.8 CBZ27864.1 - 0.03 14.7 0.0 0.04 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) zf-RING_4 PF14570.1 CBZ27864.1 - 0.1 12.1 0.2 0.1 12.1 0.2 3.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-4CXXC_R1 PF10497.4 CBZ27864.1 - 0.2 11.7 8.6 0.55 10.3 6.0 1.7 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PyrI_C PF02748.10 CBZ27864.1 - 0.71 9.3 7.8 5.4 6.5 0.1 3.2 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C3HC4_3 PF13920.1 CBZ27864.1 - 10 5.9 13.0 6.9 6.4 0.1 3.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PseudoU_synth_1 PF01416.15 CBZ27865.1 - 1.3e-12 48.0 0.0 5.4e-08 33.2 0.0 3.1 2 1 0 2 2 2 2 tRNA pseudouridine synthase ParA PF10609.4 CBZ27866.1 - 2.5e-36 123.3 0.0 5.2e-36 122.3 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CBZ27866.1 - 1.2e-15 57.4 0.0 2.1e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 CBZ27866.1 - 6.9e-08 31.8 0.1 3.9e-06 26.1 0.1 2.8 3 0 0 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.1 CBZ27866.1 - 1.3e-06 28.3 0.1 7.5e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 CBZ27866.1 - 6.3e-06 25.4 0.1 0.00034 19.7 0.1 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.1 CBZ27866.1 - 0.00017 21.0 0.2 0.00037 19.9 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CBZ27866.1 - 0.001 18.7 3.2 0.18 11.5 1.5 3.0 2 1 1 3 3 3 1 Part of AAA domain Fer4_NifH PF00142.13 CBZ27866.1 - 0.0024 17.1 0.0 0.0051 16.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NACHT PF05729.7 CBZ27866.1 - 0.013 15.1 0.3 0.025 14.2 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_26 PF13500.1 CBZ27866.1 - 0.051 13.1 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CBZ27866.1 - 0.056 14.2 0.2 0.12 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.7 CBZ27866.1 - 0.06 12.6 0.2 0.2 10.9 0.2 1.8 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF258 PF03193.11 CBZ27866.1 - 0.069 12.3 0.1 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 CBZ27866.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.1 CBZ27866.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-C4_ClpX PF06689.8 CBZ27866.1 - 0.11 11.9 2.4 0.26 10.8 1.7 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger RNA_helicase PF00910.17 CBZ27866.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 CBZ27866.1 - 0.17 10.6 0.1 0.29 9.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.12 CBZ27866.1 - 0.2 11.0 0.4 0.36 10.2 0.3 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1358 PF07096.6 CBZ27867.1 - 0.0014 18.2 0.0 0.0037 16.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) ATP-synt_C PF00137.16 CBZ27869.1 - 1e-16 60.5 13.5 1e-16 60.5 9.4 1.6 2 0 0 2 2 2 1 ATP synthase subunit C DUF2474 PF10617.4 CBZ27870.1 - 0.01 15.4 0.5 0.028 13.9 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) ATP_bind_1 PF03029.12 CBZ27871.1 - 1.7e-48 165.2 0.0 3.4e-47 160.9 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CBZ27871.1 - 0.0017 19.1 2.4 0.03 15.1 0.2 2.7 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CBZ27871.1 - 0.005 16.7 0.0 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CBZ27871.1 - 0.02 15.0 0.2 0.14 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CBZ27871.1 - 0.053 13.7 0.1 0.35 11.0 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CBZ27871.1 - 0.088 12.5 0.2 0.47 10.2 0.0 2.3 3 0 0 3 3 3 0 Part of AAA domain AAA_18 PF13238.1 CBZ27871.1 - 0.54 10.5 5.8 0.33 11.2 0.2 2.8 2 1 1 3 3 3 0 AAA domain PAP_assoc PF03828.14 CBZ27872.1 - 4.2e-08 33.0 0.0 8.1e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBZ27872.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain LRR_6 PF13516.1 CBZ27873.1 - 1.1e-25 86.7 16.9 0.26 11.4 0.0 12.3 12 0 0 12 12 12 10 Leucine Rich repeat LRR_4 PF12799.2 CBZ27873.1 - 4.6e-12 45.2 10.3 0.007 15.9 0.0 5.7 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ27873.1 - 2.3e-10 39.0 6.6 1.3 9.3 0.0 9.3 10 0 0 10 10 10 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ27873.1 - 1e-09 36.9 11.5 3.8 8.1 0.0 9.5 9 0 0 9 9 9 2 Leucine rich repeat LRR_8 PF13855.1 CBZ27873.1 - 6.4e-05 22.6 17.2 0.28 10.9 0.3 6.1 3 2 3 6 6 6 5 Leucine rich repeat Glycos_transf_2 PF00535.21 CBZ27875.1 - 0.096 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 MAPKK1_Int PF08923.5 CBZ27877.1 - 0.00098 18.7 0.0 0.034 13.7 0.0 2.0 2 0 0 2 2 2 2 Mitogen-activated protein kinase kinase 1 interacting DUF525 PF04379.9 CBZ27878.1 - 7.5e-18 64.2 0.0 2.1e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF525) Taxilin PF09728.4 CBZ27880.1 - 9.1e-06 24.9 44.1 2.9e-05 23.3 29.8 2.0 1 1 0 1 1 1 1 Myosin-like coiled-coil protein AAA_13 PF13166.1 CBZ27880.1 - 0.00027 19.5 13.9 0.00027 19.5 9.6 2.1 1 1 1 2 2 2 1 AAA domain Tropomyosin_1 PF12718.2 CBZ27880.1 - 0.0086 15.9 44.4 0.14 11.9 9.6 4.1 1 1 1 3 3 3 3 Tropomyosin like BRE1 PF08647.6 CBZ27880.1 - 0.022 14.7 6.5 0.022 14.7 4.5 4.0 1 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.5 CBZ27880.1 - 0.025 14.7 24.6 0.13 12.3 6.2 3.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 CBZ27880.1 - 0.056 12.6 3.4 0.92 8.6 0.1 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TroA PF01297.12 CBZ27880.1 - 0.31 10.2 4.4 0.98 8.6 0.0 2.6 1 1 1 2 2 2 0 Periplasmic solute binding protein family Filament PF00038.16 CBZ27880.1 - 0.51 9.7 42.8 0.65 9.4 11.7 3.7 1 1 2 3 3 3 0 Intermediate filament protein DUF2730 PF10805.3 CBZ27880.1 - 4.6 7.0 16.1 1.4 8.7 1.9 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) GAS PF13851.1 CBZ27880.1 - 6.2 5.9 41.6 8.7 5.4 8.6 4.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 CBZ27880.1 - 8.9 6.1 24.3 1.8 8.3 1.1 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) PPR_2 PF13041.1 CBZ27881.1 - 8.7e-14 51.2 3.8 3.1e-07 30.2 0.0 3.9 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.1 CBZ27881.1 - 3.1e-10 39.5 4.6 9.5e-05 22.3 0.1 4.4 4 1 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.15 CBZ27881.1 - 1.9e-06 27.4 9.7 0.017 15.0 0.1 5.2 5 1 0 5 5 5 2 PPR repeat MNE1 PF13762.1 CBZ27881.1 - 0.15 12.1 0.2 1.5 8.9 0.1 2.4 1 1 2 3 3 3 0 Mitochondrial splicing apparatus component Med3 PF11593.3 CBZ27881.1 - 0.23 10.6 3.3 0.3 10.2 2.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Cpn10 PF00166.16 CBZ27882.1 - 5.1e-24 84.0 0.3 5.7e-24 83.8 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cpn10 PF00166.16 CBZ27884.1 - 5.1e-24 84.0 0.3 5.7e-24 83.8 0.2 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Thioredoxin PF00085.15 CBZ27886.1 - 1.5e-56 188.4 0.0 1.7e-27 95.0 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 CBZ27886.1 - 2.8e-20 72.7 0.1 6.6e-20 71.5 0.1 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 CBZ27886.1 - 3.6e-19 69.0 0.4 2.2e-08 34.2 0.0 3.5 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ27886.1 - 1.9e-12 47.1 0.1 1.1e-05 25.4 0.1 4.0 2 2 2 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CBZ27886.1 - 2.6e-12 46.5 0.1 4.5e-07 29.7 0.0 2.7 2 1 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 CBZ27886.1 - 6.2e-08 32.3 0.1 0.00061 19.4 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 CBZ27886.1 - 7.3e-07 28.8 0.1 0.0012 18.4 0.0 2.3 2 0 0 2 2 2 2 Redoxin HyaE PF07449.6 CBZ27886.1 - 7.7e-05 22.5 0.0 0.17 11.7 0.0 2.4 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.1 CBZ27886.1 - 0.00018 21.3 0.0 1.1 9.0 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain TraF PF13728.1 CBZ27886.1 - 0.00096 18.6 0.0 1 8.7 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_4 PF13462.1 CBZ27886.1 - 0.0043 17.0 0.4 2.9 7.8 0.0 3.0 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_9 PF14595.1 CBZ27886.1 - 0.027 14.0 0.1 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Glutaredoxin PF00462.19 CBZ27886.1 - 0.028 14.3 0.1 1 9.3 0.0 2.8 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_5 PF13743.1 CBZ27886.1 - 0.066 12.7 0.1 6.3 6.3 0.0 3.2 2 2 1 3 3 3 0 Thioredoxin Thioredoxin PF00085.15 CBZ27887.1 - 9.5e-19 67.0 0.0 1.3e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBZ27887.1 - 1.8e-05 24.7 0.2 0.029 14.4 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CBZ27887.1 - 2.3e-05 24.5 0.1 0.00026 21.1 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBZ27887.1 - 0.0075 16.2 0.1 0.018 15.0 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBZ27887.1 - 0.085 12.5 0.0 0.47 10.1 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family DUF2012 PF09430.5 CBZ27888.1 - 2.5e-32 111.3 0.1 3.2e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 CBZ27888.1 - 0.0017 18.3 0.1 0.004 17.1 0.1 1.7 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain COX4 PF02936.9 CBZ27888.1 - 0.1 12.3 0.1 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV SNARE PF05739.14 CBZ27889.1 - 1.4e-08 34.2 3.9 1.4e-08 34.2 2.7 2.4 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.6 CBZ27889.1 - 1.7e-06 28.3 1.7 3.2e-05 24.2 0.0 2.5 1 1 1 2 2 2 1 Syntaxin 6, N-terminal CALCOCO1 PF07888.6 CBZ27889.1 - 5.6e-05 21.6 8.7 6.6e-05 21.3 6.0 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like CRPA PF05745.6 CBZ27889.1 - 0.0073 16.1 0.7 0.011 15.4 0.1 1.6 2 0 0 2 2 2 1 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) FAM60A PF15396.1 CBZ27889.1 - 0.078 12.7 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Laminin_II PF06009.7 CBZ27889.1 - 0.11 12.2 2.4 0.39 10.4 0.2 2.3 2 1 0 2 2 2 0 Laminin Domain II Snapin_Pallidin PF14712.1 CBZ27889.1 - 0.39 11.0 5.1 6.8 7.0 0.8 2.8 2 1 0 2 2 2 0 Snapin/Pallidin EMP24_GP25L PF01105.19 CBZ27889.1 - 0.45 10.2 2.4 0.39 10.4 0.2 1.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF2951 PF11166.3 CBZ27889.1 - 0.47 10.3 6.8 0.11 12.3 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DivIVA PF05103.8 CBZ27889.1 - 0.81 9.7 6.3 8.1 6.5 3.9 2.5 1 1 1 2 2 2 0 DivIVA protein Pentapeptide_4 PF13599.1 CBZ27890.1 - 4.5e-08 32.7 12.0 2.9e-07 30.2 0.5 2.7 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 CBZ27890.1 - 5.8e-06 26.1 9.0 0.00045 20.0 0.0 4.2 3 1 2 5 5 5 4 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 CBZ27890.1 - 0.00024 20.2 3.0 0.00062 18.9 0.0 3.0 3 1 1 4 4 4 2 Pentapeptide repeats (8 copies) DAGK_cat PF00781.19 CBZ27891.1 - 1.1e-13 50.7 0.1 1.5e-12 47.0 0.0 2.3 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain zf-RING_UBOX PF13445.1 CBZ27893.1 - 0.02 14.6 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RCC1 PF00415.13 CBZ27894.1 - 1.7e-76 252.2 30.4 1.3e-15 57.2 0.2 12.0 11 1 0 11 11 11 11 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ27894.1 - 1.5e-41 139.1 79.6 1.2e-07 31.0 1.3 12.2 13 0 0 13 13 13 10 Regulator of chromosome condensation (RCC1) repeat Methyltransf_9 PF08003.6 CBZ27894.1 - 0.24 10.0 0.0 6.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Peptidase_C25_C PF03785.9 CBZ27894.1 - 0.27 11.0 1.3 37 4.2 0.0 4.5 4 1 1 5 5 5 0 Peptidase family C25, C terminal ig-like domain CBM_X PF06204.6 CBZ27894.1 - 2.2 7.8 15.6 18 4.8 0.0 5.9 7 0 0 7 7 7 0 Putative carbohydrate binding domain RCC1 PF00415.13 CBZ27895.1 - 8.1e-61 202.0 37.0 1.7e-12 47.3 0.1 12.8 13 0 0 13 13 13 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ27895.1 - 7.7e-35 117.7 64.4 2.2e-05 23.9 0.5 12.4 12 0 0 12 12 12 10 Regulator of chromosome condensation (RCC1) repeat RRM_1 PF00076.17 CBZ27896.1 - 3.1e-11 42.7 0.1 4.7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27896.1 - 3.1e-09 36.6 0.0 5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27896.1 - 0.00096 18.9 0.1 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fmp27_SW PF10305.4 CBZ27897.1 - 9.9 6.6 8.6 17 5.8 0.3 3.0 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain RRM_1 PF00076.17 CBZ27898.1 - 1.2e-08 34.4 0.1 1.8e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27898.1 - 2.4e-08 33.8 0.0 3.7e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27898.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GSHPx PF00255.14 CBZ27900.1 - 6e-38 128.5 0.2 7.6e-38 128.2 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CBZ27900.1 - 8.9e-05 22.1 0.1 0.00018 21.1 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CBZ27900.1 - 0.019 14.4 0.0 0.031 13.8 0.0 1.6 1 1 0 1 1 1 0 Redoxin GSHPx PF00255.14 CBZ27901.1 - 5.2e-38 128.7 0.2 6.6e-38 128.4 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CBZ27901.1 - 0.00011 21.9 0.1 0.00021 20.9 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CBZ27901.1 - 0.026 14.0 0.0 0.041 13.4 0.0 1.6 1 1 0 1 1 1 0 Redoxin AsnA PF03590.10 CBZ27902.1 - 4.8e-95 317.6 0.0 5.8e-91 304.2 0.0 2.1 1 1 1 2 2 2 2 Aspartate-ammonia ligase tRNA-synt_2 PF00152.15 CBZ27902.1 - 0.00048 19.0 0.1 0.028 13.1 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) Nuc-transf PF10127.4 CBZ27904.1 - 0.0068 15.7 0.1 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Predicted nucleotidyltransferase IF3_N PF05198.11 CBZ27904.1 - 0.024 14.5 0.1 0.061 13.2 0.1 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain DUF3141 PF11339.3 CBZ27904.1 - 0.039 12.2 0.2 0.05 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3141) Exo_endo_phos PF03372.18 CBZ27905.1 - 9.7e-11 42.0 0.0 1.5e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family XRN_N PF03159.13 CBZ27905.1 - 0.075 12.4 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus FYRC PF05965.9 CBZ27906.1 - 0.00044 19.9 0.0 0.00083 19.1 0.0 1.4 1 0 0 1 1 1 1 F/Y rich C-terminus Ribosomal_S9 PF00380.14 CBZ27907.1 - 1.1e-29 103.0 0.9 1.3e-29 102.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_S9 PF00380.14 CBZ27908.1 - 1.1e-29 103.0 0.9 1.3e-29 102.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HSP70 PF00012.15 CBZ27909.1 - 6.6e-77 258.8 0.1 2.5e-40 138.0 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 CBZ27909.1 - 0.00086 17.9 0.1 0.51 8.8 0.0 3.2 2 1 1 3 3 3 2 MreB/Mbl protein StbA PF06406.6 CBZ27909.1 - 0.061 12.2 0.0 0.19 10.6 0.0 1.8 2 0 0 2 2 2 0 StbA protein OGFr_N PF04664.8 CBZ27910.1 - 7.7e-05 22.1 0.1 0.024 13.9 0.0 2.3 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region Glutaredoxin PF00462.19 CBZ27911.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin PIF1 PF05970.9 CBZ27912.1 - 3.1e-05 23.0 0.0 5.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase IstB_IS21 PF01695.12 CBZ27912.1 - 7e-05 22.3 0.2 0.001 18.5 0.1 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein SRP54 PF00448.17 CBZ27912.1 - 0.0054 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain DUF815 PF05673.8 CBZ27912.1 - 0.024 13.5 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 CBZ27912.1 - 0.034 13.7 0.2 0.073 12.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial dnaA protein DZR PF12773.2 CBZ27912.1 - 0.057 13.2 2.0 6.4 6.6 1.6 2.6 1 1 1 2 2 2 0 Double zinc ribbon DUF3395 PF11875.3 CBZ27913.1 - 6.7e-49 165.4 0.0 1.2e-48 164.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 CBZ27913.1 - 5.5e-15 54.8 0.3 1e-14 54.0 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Mcp5_PH PF12814.2 CBZ27914.1 - 3.2e-25 88.4 0.5 5.2e-25 87.7 0.3 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology NMD3 PF04981.8 CBZ27916.1 - 1.1e-74 250.5 4.2 1.5e-74 250.1 2.9 1.2 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 CBZ27916.1 - 4.2 7.2 11.0 0.76 9.6 2.2 2.7 2 1 0 2 2 2 0 Double zinc ribbon Pkinase PF00069.20 CBZ27917.1 - 8.7e-33 113.5 0.0 2.5e-32 112.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27917.1 - 2.4e-11 43.1 0.0 2.3e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBZ27917.1 - 0.0031 16.3 0.0 0.0046 15.8 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase PKD_channel PF08016.7 CBZ27918.1 - 1.5e-06 26.9 9.3 2.4e-06 26.2 6.4 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 CBZ27918.1 - 6.2e-06 25.5 12.5 6.2e-06 25.5 8.7 2.2 2 0 0 2 2 2 1 Ion transport protein PRKCSH_1 PF13015.1 CBZ27919.1 - 7.8e-22 77.3 0.5 2.2e-21 75.9 0.3 1.8 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 CBZ27919.1 - 0.0012 19.5 1.2 0.002 18.9 0.2 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Imm6 PF14434.1 CBZ27919.1 - 0.055 13.1 0.4 0.13 11.9 0.2 1.6 1 1 0 1 1 1 0 Immunity protein Imm6 DUF4140 PF13600.1 CBZ27919.1 - 3.1 8.2 9.4 2.4 8.6 0.2 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 CBZ27919.1 - 4.4 6.2 12.2 0.91 8.4 2.6 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF3283 PF11686.3 CBZ27920.1 - 0.028 14.2 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) Dynein_heavy PF03028.10 CBZ27922.1 - 9.2e-192 638.8 0.0 4.3e-191 636.5 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ27922.1 - 8.6e-120 399.9 10.6 8.6e-120 399.9 7.4 2.9 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ27922.1 - 2.1e-95 318.6 0.0 4.6e-95 317.5 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ27922.1 - 3.1e-67 226.3 0.2 6.9e-67 225.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ27922.1 - 4.6e-60 202.3 0.3 4.6e-60 202.3 0.2 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 CBZ27922.1 - 4.5e-52 176.9 7.7 1e-51 175.7 5.3 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBZ27922.1 - 2.5e-33 115.3 0.0 2e-32 112.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBZ27922.1 - 2.7e-24 85.4 0.0 6.3e-07 29.2 0.0 5.9 5 2 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ27922.1 - 8e-07 29.3 0.0 1.6 8.9 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ27922.1 - 4.1e-06 26.8 8.9 1.1 9.1 0.0 7.2 5 2 2 7 7 7 2 AAA ATPase domain AAA_22 PF13401.1 CBZ27922.1 - 6.3e-05 23.1 3.7 6 7.0 0.0 6.4 7 0 0 7 7 7 1 AAA domain AAA_30 PF13604.1 CBZ27922.1 - 6.7e-05 22.5 1.1 0.9 9.0 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 CBZ27922.1 - 0.0073 17.1 0.0 7.6 7.3 0.0 4.7 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 CBZ27922.1 - 0.022 14.9 0.0 4.5 7.5 0.0 4.0 4 0 0 4 4 4 0 RNA helicase FtsK_SpoIIIE PF01580.13 CBZ27922.1 - 0.022 14.2 0.0 0.022 14.2 0.0 3.6 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_19 PF13245.1 CBZ27922.1 - 0.11 12.2 6.1 2.9 7.7 0.0 4.3 4 0 0 4 4 3 0 Part of AAA domain Aldo_ket_red PF00248.16 CBZ27923.1 - 0.0014 17.4 0.0 0.93 8.2 0.0 2.4 2 0 0 2 2 2 2 Aldo/keto reductase family Peptidase_M28 PF04389.12 CBZ27924.1 - 0.00075 19.2 0.1 0.0018 18.0 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M28 Fer2 PF00111.22 CBZ27925.1 - 5.8e-12 45.1 1.0 9.4e-12 44.5 0.7 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RRM_1 PF00076.17 CBZ27926.1 - 3.4e-08 33.0 0.0 6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27926.1 - 2.1e-05 24.4 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27926.1 - 0.00051 19.8 0.0 0.00084 19.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.5 CBZ27926.1 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Ribosomal_L19e PF01280.15 CBZ27928.1 - 0.025 14.3 0.3 0.062 13.0 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein L19e TROVE PF05731.6 CBZ27931.1 - 4e-44 150.9 0.1 9.3e-44 149.7 0.0 1.6 1 1 0 1 1 1 1 TROVE domain WD40 PF00400.27 CBZ27931.1 - 4.5e-22 77.0 25.4 0.0012 18.6 0.1 9.9 10 0 0 10 10 10 5 WD domain, G-beta repeat DUF4062 PF13271.1 CBZ27931.1 - 0.00025 21.0 0.0 0.00098 19.0 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4062) MFS_1_like PF12832.2 CBZ27931.1 - 0.51 10.1 0.1 1.4 8.7 0.1 1.7 1 0 0 1 1 1 0 MFS_1 like family Methyltransf_16 PF10294.4 CBZ27931.1 - 0.83 9.0 0.0 2 7.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase VirE PF05272.6 CBZ27931.1 - 3.8 6.9 0.0 7.2 6.0 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E Glyco_transf_8 PF01501.15 CBZ27931.1 - 4.3 6.5 0.0 43 3.3 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 8 Ax_dynein_light PF10211.4 CBZ27932.1 - 2e-51 174.5 5.9 2e-51 174.5 4.1 1.4 2 0 0 2 2 2 1 Axonemal dynein light chain IncA PF04156.9 CBZ27932.1 - 0.017 14.7 3.8 0.027 14.0 2.6 1.3 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 CBZ27932.1 - 0.18 10.1 2.8 0.28 9.5 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HMD PF03201.11 CBZ27934.1 - 0.11 12.4 1.4 0.35 10.8 0.1 2.4 2 1 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PseudoU_synth_2 PF00849.17 CBZ27936.1 - 7.4e-14 51.9 3.3 3.7e-07 30.1 0.0 4.5 3 2 0 3 3 3 2 RNA pseudouridylate synthase TT_ORF2 PF02957.10 CBZ27936.1 - 0.92 10.2 7.5 4.2 8.0 1.4 3.5 4 0 0 4 4 4 0 TT viral ORF2 zf-RING_2 PF13639.1 CBZ27937.1 - 5.8e-09 35.6 5.4 3.3e-07 30.0 1.4 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 CBZ27937.1 - 1.2e-07 31.2 3.8 3.5e-06 26.5 1.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ27937.1 - 1.7e-05 24.7 6.8 3.1e-05 23.8 1.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ27937.1 - 0.0039 16.8 4.4 0.0091 15.6 1.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBZ27937.1 - 0.0062 16.1 1.1 0.0062 16.1 0.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CBZ27937.1 - 0.011 15.8 0.5 0.26 11.4 0.3 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger Baculo_IE-1 PF05290.6 CBZ27937.1 - 0.026 14.2 0.2 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Snapin_Pallidin PF14712.1 CBZ27937.1 - 0.14 12.4 1.8 0.87 9.9 0.1 2.1 2 0 0 2 2 2 0 Snapin/Pallidin zf-C4H2 PF10146.4 CBZ27937.1 - 0.21 11.5 4.4 0.41 10.6 0.1 2.8 2 1 0 2 2 2 0 Zinc finger-containing protein Uds1 PF15456.1 CBZ27937.1 - 1.4 8.9 9.7 2.6 8.0 6.8 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Beta_helix PF13229.1 CBZ27938.1 - 0.0011 18.7 0.0 0.041 13.6 0.0 2.4 1 1 0 1 1 1 1 Right handed beta helix region Ribosomal_60s PF00428.14 CBZ27938.1 - 0.0048 17.2 3.0 0.0048 17.2 2.1 7.1 8 2 0 8 8 8 1 60s Acidic ribosomal protein FAM176 PF14851.1 CBZ27938.1 - 0.029 14.0 9.9 0.081 12.6 1.1 3.4 3 0 0 3 3 3 0 FAM176 family DnaJ PF00226.26 CBZ27940.1 - 1.9e-21 75.5 0.1 4.9e-21 74.2 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.1 CBZ27940.1 - 4e-05 22.9 0.3 0.00013 21.2 0.0 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing Aldo_ket_red PF00248.16 CBZ27941.1 - 1.8e-32 112.3 0.0 6.8e-27 94.0 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family LRR_4 PF12799.2 CBZ27942.1 - 7.5e-15 54.1 1.9 3.8e-06 26.3 0.3 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ27942.1 - 2.8e-13 49.4 3.6 0.00016 21.3 1.5 4.2 3 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CBZ27942.1 - 1.3e-07 30.6 12.0 0.66 10.2 0.3 6.8 5 2 2 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 CBZ27942.1 - 6.6e-06 25.5 8.0 3.7 8.1 0.1 5.9 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 CBZ27942.1 - 7.9e-05 22.3 3.0 2.3 8.5 0.1 4.2 2 1 1 3 3 3 2 Leucine Rich repeat DUF572 PF04502.8 CBZ27942.1 - 7.5 5.6 12.5 16 4.5 8.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF572) PTCB-BRCT PF12738.2 CBZ27943.1 - 3.9e-09 36.2 0.0 0.00017 21.3 0.0 4.1 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 CBZ27943.1 - 7.2e-05 22.8 0.0 1.6 8.9 0.0 4.5 5 0 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain Na_Pi_cotrans PF02690.10 CBZ27943.1 - 0.62 9.7 0.0 1.6 8.4 0.0 1.6 1 0 0 1 1 1 0 Na+/Pi-cotransporter HSP70 PF00012.15 CBZ27944.1 - 3.3e-251 834.4 4.3 3.8e-251 834.2 3.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ27944.1 - 2.2e-18 65.9 0.4 1.8e-16 59.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.15 CBZ27944.1 - 0.0018 17.6 0.0 0.8 8.9 0.0 2.5 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 CBZ27944.1 - 0.0024 17.7 2.3 0.083 12.7 0.5 3.6 2 1 0 2 2 2 1 Cell division protein FtsA DDR PF08841.5 CBZ27944.1 - 0.023 13.5 0.1 3 6.5 0.0 2.4 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CBZ27944.1 - 0.035 13.2 0.1 0.035 13.2 0.1 2.7 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase DnaJ PF00226.26 CBZ27947.1 - 5.2e-23 80.5 0.2 1.1e-22 79.4 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.1 CBZ27947.1 - 7.3e-11 41.7 0.0 2.6e-05 23.5 0.0 2.7 1 1 1 2 2 2 2 X-domain of DnaJ-containing GRAS PF03514.9 CBZ27947.1 - 0.096 11.3 0.2 0.17 10.5 0.2 1.3 1 0 0 1 1 1 0 GRAS domain family Cupin_8 PF13621.1 CBZ27949.1 - 6.2e-56 189.6 0.0 7.2e-55 186.2 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain PgaD PF13994.1 CBZ27951.1 - 1.4 8.3 5.1 0.27 10.7 0.3 2.1 2 0 0 2 2 2 0 PgaD-like protein Coleoptericin PF06286.6 CBZ27952.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Coleoptericin DNA_ligase_OB_2 PF14743.1 CBZ27954.1 - 1.7e-20 72.4 0.1 3.2e-20 71.5 0.1 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.1 CBZ27954.1 - 1.2e-13 50.6 4.3 1.3e-13 50.4 1.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4379) DNA_ligase_A_M PF01068.16 CBZ27954.1 - 8.2e-13 48.1 0.0 9.4e-07 28.3 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain Peptidase_M74 PF03411.8 CBZ27954.1 - 0.041 13.1 5.4 2.6 7.2 1.7 2.3 1 1 1 2 2 2 0 Penicillin-insensitive murein endopeptidase PhnA_Zn_Ribbon PF08274.7 CBZ27954.1 - 0.089 12.5 4.1 0.65 9.8 1.0 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon mRNA_cap_enzyme PF01331.14 CBZ27954.1 - 0.12 12.0 0.0 0.5 10.0 0.0 1.9 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.16 CBZ27955.1 - 9.8e-23 80.5 0.0 2.4e-22 79.3 0.0 1.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.1 CBZ27955.1 - 1.1e-18 66.6 0.0 2.1e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.1 CBZ27955.1 - 0.00089 19.0 0.7 0.002 17.9 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4379) Zn-ribbon_8 PF09723.5 CBZ27955.1 - 0.0098 15.8 0.4 0.028 14.3 0.3 1.8 1 0 0 1 1 1 1 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CBZ27955.1 - 0.26 11.1 2.2 3.8 7.4 0.1 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Thioredoxin PF00085.15 CBZ27956.1 - 0.0074 15.9 0.0 0.067 12.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin MMR_HSR1 PF01926.18 CBZ27957.1 - 6.3e-16 58.3 0.0 3.1e-13 49.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ27957.1 - 4.1e-06 26.1 0.0 8.7e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBZ27957.1 - 0.00071 19.0 0.0 1.3 8.4 0.1 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBZ27957.1 - 0.00097 18.3 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBZ27957.1 - 0.0034 17.2 1.2 0.14 11.9 0.2 2.7 1 1 1 2 2 2 1 Dynamin family Allexi_40kDa PF05549.6 CBZ27957.1 - 0.22 10.7 0.3 2.7 7.1 0.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Prefoldin PF02996.12 CBZ27958.1 - 2.8e-26 91.5 1.9 3.8e-26 91.0 0.9 1.5 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CBZ27958.1 - 0.015 15.0 4.3 0.65 9.7 0.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit KxDL PF10241.4 CBZ27958.1 - 0.077 12.8 0.6 6.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF3847 PF12958.2 CBZ27958.1 - 0.081 12.6 2.9 7.8 6.3 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) DUF972 PF06156.8 CBZ27958.1 - 1.6 9.0 6.8 7.1 7.0 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) WD40 PF00400.27 CBZ27960.1 - 1.3e-24 85.1 22.3 2.1e-07 30.5 0.7 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat WWE PF02825.15 CBZ27960.1 - 5.7e-06 25.6 0.2 1.5e-05 24.3 0.1 1.7 1 1 0 1 1 1 1 WWE domain DUF1364 PF07102.7 CBZ27960.1 - 0.41 10.5 3.2 0.96 9.3 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1364) DnaJ PF00226.26 CBZ27961.1 - 3.9e-20 71.3 0.9 7.6e-20 70.4 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain MORN PF02493.15 CBZ27962.1 - 1.8e-45 150.0 125.9 0.0001 21.8 0.3 24.6 26 0 0 26 26 26 20 MORN repeat FYVE PF01363.16 CBZ27962.1 - 1e-25 89.4 16.0 5.3e-18 64.6 4.5 2.7 2 0 0 2 2 2 2 FYVE zinc finger MRP-63 PF14978.1 CBZ27962.1 - 0.29 11.6 0.0 0.62 10.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 Cyt-b5 PF00173.23 CBZ27963.1 - 1.5e-17 63.1 0.0 2.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4496 PF14908.1 CBZ27963.1 - 0.032 14.1 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4496) DUF3628 PF12300.3 CBZ27964.1 - 2.7 8.0 17.1 0.069 13.1 4.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) DUF2668 PF10873.3 CBZ27966.1 - 0.00081 19.5 0.2 0.0019 18.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) IncA PF04156.9 CBZ27966.1 - 0.0035 16.9 0.1 0.0035 16.9 0.0 1.8 2 0 0 2 2 2 1 IncA protein Shisa PF13908.1 CBZ27966.1 - 0.0063 16.6 0.4 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 CBZ27966.1 - 0.046 12.0 1.1 0.46 8.6 0.7 2.1 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Neur_chan_memb PF02932.11 CBZ27966.1 - 0.049 13.5 0.1 0.073 12.9 0.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMEM171 PF15471.1 CBZ27966.1 - 0.065 12.0 1.8 0.39 9.4 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein family 171 DUF3728 PF12528.3 CBZ27966.1 - 0.27 11.6 2.3 0.41 11.0 1.0 1.7 1 1 0 1 1 1 0 Prepilin peptidase dependent protein C (DUF3728) SHP PF03579.8 CBZ27966.1 - 1.2 8.5 4.1 0.38 10.1 0.4 2.0 2 0 0 2 2 2 0 Small hydrophobic protein Prenyltrans PF00432.16 CBZ27967.1 - 2.5e-22 78.1 13.7 0.0001 21.7 0.0 5.8 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBZ27967.1 - 1.5e-21 76.8 1.7 1.6e-15 57.4 0.0 4.4 3 1 1 4 4 4 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBZ27967.1 - 1.8e-05 24.7 0.1 0.012 15.5 0.0 2.8 2 1 0 2 2 2 2 Prenyltransferase-like COG7 PF10191.4 CBZ27968.1 - 3.4e-11 41.8 8.2 0.0037 15.2 0.4 5.3 5 1 0 6 6 6 5 Golgi complex component 7 (COG7) MoCF_biosynth PF00994.19 CBZ27968.1 - 0.0017 17.7 0.0 0.091 12.1 0.0 2.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain DUF445 PF04286.7 CBZ27968.1 - 0.022 14.3 0.3 6.9 6.0 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF445) GAT PF03127.9 CBZ27968.1 - 0.045 13.7 6.8 1.9 8.5 0.2 3.4 3 0 0 3 3 3 0 GAT domain PhoD PF09423.5 CBZ27969.1 - 0.0011 17.6 0.0 0.014 14.0 0.0 2.2 2 1 0 2 2 2 1 PhoD-like phosphatase stn_TNFRSF12A PF12191.3 CBZ27969.1 - 0.19 11.7 1.2 0.76 9.8 0.1 2.1 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Abhydrolase_6 PF12697.2 CBZ27972.1 - 1.5e-21 77.2 0.7 2.3e-21 76.7 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ27972.1 - 6.4e-07 29.2 0.0 2.1e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ27972.1 - 0.0005 19.6 0.4 0.46 9.9 0.2 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold DUF915 PF06028.6 CBZ27972.1 - 0.0018 17.3 0.0 0.0047 16.0 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) RRM_1 PF00076.17 CBZ27973.1 - 1.2e-16 60.1 0.0 1.8e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ27973.1 - 1.5e-14 53.7 0.0 2.4e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ27973.1 - 1.1e-11 44.3 0.0 1.8e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glutaredoxin PF00462.19 CBZ27974.1 - 2.7e-06 27.2 0.1 8.2e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 CBZ27974.1 - 1.6e-05 25.0 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3918 PF13056.1 CBZ27974.1 - 0.013 14.7 0.5 0.031 13.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) GST_N_2 PF13409.1 CBZ27974.1 - 0.054 13.5 0.0 0.26 11.2 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CBZ27974.1 - 0.085 13.3 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CBZ27974.1 - 0.13 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain 3HCDH_N PF02737.13 CBZ27975.1 - 7.7e-51 172.2 3.5 1.5e-50 171.3 2.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH PF00378.15 CBZ27975.1 - 3.8e-40 137.5 0.3 7.4e-40 136.6 0.2 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH PF00725.17 CBZ27975.1 - 3.6e-36 123.4 0.4 1.7e-23 82.8 0.0 3.3 4 0 0 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBZ27975.1 - 5.6e-06 26.2 0.8 1.6e-05 24.8 0.6 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 CBZ27975.1 - 0.00081 19.1 0.7 0.0018 18.0 0.5 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 CBZ27975.1 - 0.0016 18.8 2.0 0.0077 16.6 1.4 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Penicillinase_R PF03965.11 CBZ27975.1 - 0.011 15.8 0.1 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 Penicillinase repressor DAO PF01266.19 CBZ27975.1 - 0.051 12.4 0.0 0.08 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 CBZ27975.1 - 1.4 9.0 5.1 20 5.3 1.7 3.1 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SNF2_N PF00176.18 CBZ27976.1 - 4.2e-29 101.2 0.1 3e-20 72.2 0.0 2.8 2 1 0 2 2 2 2 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CBZ27976.1 - 3.3e-08 33.2 6.8 1.5e-07 31.1 3.4 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ27976.1 - 2.6e-07 30.5 5.7 2.6e-07 30.5 3.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ27976.1 - 6.6e-07 28.9 5.7 6.6e-07 28.9 3.9 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ27976.1 - 2e-06 27.3 4.6 7.2e-06 25.5 3.2 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 CBZ27976.1 - 2.1e-06 27.4 0.0 4.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 CBZ27976.1 - 7.6e-06 25.5 4.7 3.2e-05 23.5 3.2 2.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CBZ27976.1 - 0.00027 20.7 5.6 0.00027 20.7 3.9 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING DEAD PF00270.24 CBZ27976.1 - 0.00098 18.6 0.0 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 CBZ27976.1 - 0.0014 18.2 2.3 0.0039 16.8 1.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Peptidase_M3 PF01432.15 CBZ27977.1 - 1.8e-117 393.2 0.0 1.3e-116 390.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.1 CBZ27977.1 - 0.064 12.6 0.3 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like PQQ_2 PF13360.1 CBZ27978.1 - 0.0049 16.3 0.1 0.013 14.9 0.0 1.7 2 0 0 2 2 2 1 PQQ-like domain EF-hand_1 PF00036.27 CBZ27979.1 - 0.069 12.4 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 EF hand U-box PF04564.10 CBZ27980.1 - 0.00042 20.2 0.0 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 U-box domain Pro_dh PF01619.13 CBZ27981.1 - 1.2e-54 185.4 0.4 1.8e-54 184.8 0.3 1.2 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.19 CBZ27981.1 - 1.8e-05 24.1 0.1 0.0035 16.6 0.0 2.9 2 1 1 3 3 3 1 Xylose isomerase-like TIM barrel EF-hand_7 PF13499.1 CBZ27981.1 - 0.086 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 CBZ27981.1 - 0.11 11.9 0.0 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 EF hand CTP_transf_1 PF01148.15 CBZ27982.1 - 1.9e-61 207.9 20.2 2.7e-61 207.5 14.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S28e PF01200.13 CBZ27983.1 - 1.9e-29 101.2 2.8 2.2e-29 100.9 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S28e PF01200.13 CBZ27984.1 - 1.9e-29 101.2 2.8 2.2e-29 100.9 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e MIT PF04212.13 CBZ27985.1 - 0.00069 19.4 0.4 0.002 17.9 0.1 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain LRR_1 PF00560.28 CBZ27986.1 - 1.5e-07 30.4 4.9 0.81 9.9 0.0 6.5 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 CBZ27986.1 - 2.9e-07 29.8 4.3 0.14 12.3 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.2 CBZ27986.1 - 0.00036 20.0 1.3 4 7.1 0.0 4.7 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CBZ27986.1 - 0.21 11.9 14.7 9.4 6.9 0.0 6.7 7 0 0 7 7 7 0 Leucine rich repeat LRR_8 PF13855.1 CBZ27986.1 - 0.26 11.0 5.8 15 5.4 0.0 4.9 4 2 0 4 4 4 0 Leucine rich repeat FA_desaturase PF00487.19 CBZ27988.1 - 4e-25 88.7 25.4 5.9e-25 88.1 17.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 CBZ27988.1 - 0.00073 18.7 0.1 0.0013 17.9 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) GPI2 PF06432.6 CBZ27988.1 - 8.9 5.5 11.3 0.6 9.3 4.2 1.6 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Lipid_DES PF08557.5 CBZ27989.1 - 6.5e-05 22.0 0.1 8.8e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.19 CBZ27990.1 - 4.7e-25 88.4 25.4 6.9e-25 87.9 17.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 CBZ27990.1 - 0.00078 18.6 0.1 0.0014 17.8 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) GPI2 PF06432.6 CBZ27990.1 - 8.2 5.6 11.0 0.66 9.2 4.2 1.6 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Pkinase PF00069.20 CBZ27993.1 - 9e-58 195.4 0.0 1.4e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ27993.1 - 3.9e-36 124.4 0.0 5.8e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ27993.1 - 5.6e-07 28.8 0.0 0.00012 21.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like PAS PF00989.19 CBZ27993.1 - 2.3e-06 27.3 0.0 6.8e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 PAS fold Kdo PF06293.9 CBZ27993.1 - 0.00011 21.3 0.0 0.00035 19.7 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_4 PF08448.5 CBZ27993.1 - 0.00034 20.5 0.0 0.0016 18.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 CBZ27993.1 - 0.00039 20.7 0.0 0.0016 18.7 0.0 2.1 1 0 0 1 1 1 1 PAS domain PAS_10 PF13596.1 CBZ27993.1 - 0.0064 16.7 0.0 0.025 14.8 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.1 CBZ27993.1 - 0.022 14.6 0.0 0.12 12.2 0.0 2.3 1 0 0 1 1 1 0 PAS domain DUF4079 PF13301.1 CBZ27993.1 - 0.043 13.8 0.5 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) APH PF01636.18 CBZ27993.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1469 PF07332.6 CBZ27993.1 - 0.74 9.5 3.6 1.5 8.5 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) HrpB1_HrpK PF09613.5 CBZ27995.1 - 0.084 12.3 0.1 0.084 12.3 0.0 3.0 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Radial_spoke PF04712.7 CBZ27997.1 - 0.025 13.3 0.0 0.026 13.2 0.0 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein RIIa PF02197.12 CBZ27997.1 - 0.071 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit DUF2520 PF10728.4 CBZ27999.1 - 0.094 12.1 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) NuA4 PF09340.5 CBZ28000.1 - 5.8e-07 29.0 0.0 1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 HEAT PF02985.17 CBZ28001.1 - 0.00014 21.6 0.2 0.77 9.9 0.0 4.8 3 0 0 3 3 3 1 HEAT repeat BP28CT PF08146.7 CBZ28001.1 - 0.0059 16.3 0.1 0.044 13.5 0.0 2.5 2 0 0 2 2 2 1 BP28CT (NUC211) domain Cnd1 PF12717.2 CBZ28001.1 - 0.013 15.3 0.0 0.069 12.9 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 CBZ28001.1 - 0.033 12.5 0.0 0.071 11.4 0.0 1.5 1 0 0 1 1 1 0 Adaptin N terminal region YcbB PF08664.5 CBZ28001.1 - 0.21 11.3 0.1 0.48 10.2 0.0 1.6 1 0 0 1 1 1 0 YcbB domain DNA_binding_1 PF01035.15 CBZ28002.1 - 3.8e-20 71.4 0.6 1.2e-19 69.8 0.0 2.0 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain SSI PF00720.12 CBZ28002.1 - 0.54 10.2 3.1 0.36 10.7 0.1 2.2 2 0 0 2 2 2 0 Subtilisin inhibitor-like Zn_Tnp_IS1595 PF12760.2 CBZ28003.1 - 0.028 14.2 3.8 1.7 8.5 0.9 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_6 PF13912.1 CBZ28003.1 - 0.029 14.2 0.4 0.029 14.2 0.3 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 CBZ28003.1 - 0.057 13.5 0.1 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CBZ28003.1 - 0.25 11.7 8.2 1.2 9.6 1.2 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type ELMO_CED12 PF04727.8 CBZ28007.1 - 1.4e-43 148.4 0.0 1.9e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DUF35_N PF12172.3 CBZ28007.1 - 0.05 13.5 0.4 0.13 12.1 0.3 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) LRR_6 PF13516.1 CBZ28009.1 - 1.4e-05 24.6 0.9 0.71 10.1 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 CBZ28009.1 - 0.0046 16.5 0.2 24 4.6 0.0 4.6 5 2 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ28009.1 - 0.012 15.5 2.9 9.3 6.7 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 CBZ28009.1 - 0.068 13.3 6.7 9.3 6.9 0.0 5.3 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 CBZ28009.1 - 0.31 10.8 0.2 74 3.2 0.0 3.8 4 0 0 4 4 4 0 Leucine rich repeat DUF4460 PF14687.1 CBZ28010.1 - 8.1e-09 35.2 0.7 1.7e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4461 PF14688.1 CBZ28010.1 - 0.048 12.9 5.4 0.26 10.5 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4461) Sedlin_N PF04628.8 CBZ28011.1 - 1.1e-05 25.2 0.0 2.6e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region HEAT_2 PF13646.1 CBZ28013.1 - 1.5e-29 102.0 8.6 1.5e-15 57.2 0.2 3.2 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 CBZ28013.1 - 4.3e-18 63.9 11.9 0.00086 19.5 0.1 6.1 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 CBZ28013.1 - 3.5e-09 36.8 5.1 0.00082 19.7 0.7 4.4 3 1 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 CBZ28013.1 - 8.7e-07 28.5 4.8 0.0039 17.1 0.0 5.0 5 1 0 6 6 6 2 HEAT repeat TRAM_LAG1_CLN8 PF03798.11 CBZ28014.1 - 3.6e-19 69.1 17.1 3.6e-19 69.1 11.9 1.4 2 0 0 2 2 2 1 TLC domain DUF1345 PF07077.6 CBZ28014.1 - 0.018 14.5 1.0 0.056 12.9 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) DUF4457 PF14652.1 CBZ28015.1 - 5.1e-23 81.5 0.0 4.1e-07 29.2 0.0 5.3 6 0 0 6 6 6 4 Domain of unknown function (DUF4457) DUF3770 PF12603.3 CBZ28015.1 - 1.1 8.3 0.0 1.8 7.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3770) 4HBT_2 PF13279.1 CBZ28016.1 - 4.2e-11 43.3 0.0 7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 CBZ28016.1 - 3.7e-09 36.5 0.0 1.7e-07 31.2 0.0 2.4 2 0 0 2 2 2 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 CBZ28016.1 - 0.0039 16.1 0.0 0.044 12.7 0.0 2.0 1 1 0 1 1 1 1 Acyl-ACP thioesterase MT PF12777.2 CBZ28017.1 - 0.0053 15.5 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor T4_tail_cap PF11091.3 CBZ28017.1 - 0.011 14.4 0.0 26 3.3 0.0 3.2 3 0 0 3 3 3 0 Tail-tube assembly protein IncA PF04156.9 CBZ28017.1 - 1.8 8.0 18.0 0.019 14.5 1.8 2.9 3 0 0 3 3 3 0 IncA protein SCO1-SenC PF02630.9 CBZ28019.1 - 2.4e-46 157.5 0.0 3.1e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 CBZ28019.1 - 0.00044 20.3 0.0 0.0008 19.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CBZ28019.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Adeno_PVIII PF01310.13 CBZ28019.1 - 0.017 14.9 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII Methyltransf_23 PF13489.1 CBZ28022.1 - 4.5e-14 52.4 0.0 7.8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ28022.1 - 7e-14 52.3 0.0 1.5e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ28022.1 - 2.4e-13 49.9 0.0 8.2e-06 25.4 0.0 2.7 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ28022.1 - 2.8e-11 43.7 0.0 0.00025 21.4 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ28022.1 - 1.6e-09 38.1 0.0 3.4e-08 33.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ28022.1 - 2.8e-07 30.8 0.0 1.3e-06 28.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CBZ28022.1 - 0.0014 17.5 0.0 0.003 16.5 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 CBZ28022.1 - 0.011 14.7 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CBZ28022.1 - 0.046 13.7 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PHD PF00628.24 CBZ28023.1 - 0.00063 19.3 4.6 0.0012 18.5 3.2 1.5 1 0 0 1 1 1 1 PHD-finger DUF1359 PF07097.6 CBZ28024.1 - 0.13 12.2 0.1 0.24 11.4 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1359) ATG22 PF11700.3 CBZ28025.1 - 0.026 13.0 0.0 0.047 12.1 0.0 1.3 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF2290 PF10053.4 CBZ28025.1 - 0.12 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2290) PQ-loop PF04193.9 CBZ28026.1 - 1.5e-19 69.2 1.5 2e-15 56.0 0.0 2.8 3 0 0 3 3 3 2 PQ loop repeat Pkinase PF00069.20 CBZ28028.1 - 1.6e-14 53.6 0.1 3.6e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28028.1 - 3.5e-08 32.8 0.2 0.0002 20.5 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Peptidase_C48 PF02902.14 CBZ28029.1 - 3.9e-14 52.7 0.0 3.4e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Metallophos PF00149.23 CBZ28032.1 - 5e-18 65.2 0.1 6e-16 58.4 0.1 2.6 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase Pkinase PF00069.20 CBZ28033.1 - 1.8e-34 119.0 0.0 3.2e-16 59.2 0.0 3.4 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28033.1 - 1.5e-06 27.5 0.0 3e-05 23.2 0.0 2.8 4 0 0 4 4 4 1 Protein tyrosine kinase Pkinase PF00069.20 CBZ28034.1 - 8.6e-06 25.0 0.0 0.00079 18.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain RRM_5 PF13893.1 CBZ28035.1 - 0.011 15.6 0.0 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pet191_N PF10203.4 CBZ28036.1 - 0.0014 18.5 3.9 0.066 13.2 0.3 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 FtsJ PF01728.14 CBZ28037.1 - 0.00011 22.1 0.0 0.00024 21.1 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Cornifin PF02389.10 CBZ28039.1 - 1.1e-174 576.9 212.3 2.3e-11 43.8 4.7 20.8 2 2 7 14 14 14 14 Cornifin (SPRR) family vATP-synt_AC39 PF01992.11 CBZ28039.1 - 1.3e-29 103.4 235.5 0.41 9.7 0.5 40.3 2 2 44 49 49 49 49 ATP synthase (C/AC39) subunit CUB_2 PF02408.15 CBZ28039.1 - 0.43 10.1 0.0 0.94 9.0 0.0 1.5 1 0 0 1 1 1 0 CUB-like domain Arf PF00025.16 CBZ28041.1 - 4.2e-23 81.4 0.2 2.5e-09 36.6 0.0 4.3 4 0 0 4 4 4 3 ADP-ribosylation factor family G-alpha PF00503.15 CBZ28041.1 - 7e-05 21.6 0.0 0.0051 15.5 0.0 2.5 2 1 0 2 2 2 1 G-protein alpha subunit AAA_28 PF13521.1 CBZ28041.1 - 0.0013 18.7 0.0 0.0037 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 CBZ28041.1 - 0.0015 17.7 0.0 2.6 7.2 0.0 2.9 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CBZ28041.1 - 0.0026 17.1 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CBZ28041.1 - 0.0079 16.4 0.0 0.04 14.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 CBZ28041.1 - 0.011 15.6 0.0 0.16 11.9 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CBZ28041.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 CBZ28041.1 - 0.038 14.4 0.0 0.51 10.8 0.0 2.4 3 0 0 3 3 3 0 Miro-like protein AAA_17 PF13207.1 CBZ28041.1 - 0.076 13.8 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBZ28043.1 - 2e-06 27.9 0.1 0.023 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ28043.1 - 7.1e-06 26.1 6.1 7.8e-05 22.7 0.2 3.3 3 0 0 3 3 3 2 AAA ATPase domain Kinesin PF00225.18 CBZ28043.1 - 0.024 13.3 0.1 0.055 12.1 0.0 1.5 2 0 0 2 2 2 0 Kinesin motor domain Arch_ATPase PF01637.13 CBZ28043.1 - 0.073 12.7 0.0 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase CoaE PF01121.15 CBZ28043.1 - 0.079 12.3 0.0 0.28 10.5 0.0 1.9 1 0 0 1 1 1 0 Dephospho-CoA kinase Miro PF08477.8 CBZ28043.1 - 0.12 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Ribosomal_L38e PF01781.13 CBZ28044.1 - 6.2e-31 105.9 3.8 7.4e-31 105.7 2.6 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Epimerase PF01370.16 CBZ28045.1 - 6.2e-52 176.3 0.7 8e-51 172.7 0.5 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CBZ28045.1 - 6.1e-24 84.2 0.1 1.5e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 CBZ28045.1 - 1.7e-19 69.7 0.6 9.7e-19 67.3 0.4 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 CBZ28045.1 - 9.2e-18 63.9 0.0 4.3e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CBZ28045.1 - 4.8e-16 58.5 0.0 2.4e-10 39.7 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CBZ28045.1 - 2e-06 27.9 0.8 0.00013 22.0 0.0 3.1 2 1 1 3 3 3 1 NADH(P)-binding Aminotran_5 PF00266.14 CBZ28046.1 - 5.3e-16 58.3 0.0 9.4e-16 57.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CBZ28046.1 - 0.00022 19.6 0.0 0.00033 19.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF2383 PF09537.5 CBZ28047.1 - 0.075 13.2 0.1 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Sec1 PF00995.18 CBZ28048.1 - 6.8e-110 368.3 0.0 7.9e-110 368.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family CN_hydrolase PF00795.17 CBZ28050.1 - 6.5e-29 100.5 0.0 8.4e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_6 PF12697.2 CBZ28051.1 - 0.0043 16.9 0.0 0.0073 16.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 CBZ28051.1 - 0.046 13.1 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.2 CBZ28051.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DASH_Dam1 PF08653.5 CBZ28052.1 - 0.17 11.6 6.2 45 3.9 0.0 6.0 5 0 0 5 5 5 0 DASH complex subunit Dam1 YvrJ PF12841.2 CBZ28052.1 - 0.44 9.8 2.2 1.7 8.0 0.1 3.2 3 0 0 3 3 3 0 YvrJ protein family LPP PF04728.8 CBZ28052.1 - 1.1 9.0 18.2 3.3 7.5 0.0 7.2 7 0 0 7 7 7 0 Lipoprotein leucine-zipper Cauli_DNA-bind PF03310.8 CBZ28052.1 - 4.1 7.2 6.7 3.8 7.3 0.3 3.7 3 0 0 3 3 3 0 Caulimovirus DNA-binding protein AMH_N PF04709.7 CBZ28053.1 - 0.0026 16.7 0.4 0.0028 16.6 0.3 1.1 1 0 0 1 1 1 1 Anti-Mullerian hormone, N terminal region ALMS_motif PF15309.1 CBZ28054.1 - 0.53 10.1 6.0 1.5 8.6 4.2 1.9 1 1 0 1 1 1 0 ALMS motif WD40 PF00400.27 CBZ28055.1 - 3.4e-13 48.9 8.8 0.00013 21.7 0.3 4.2 3 1 0 3 3 3 3 WD domain, G-beta repeat BUD22 PF09073.5 CBZ28055.1 - 0.0001 21.5 19.4 0.0001 21.5 13.4 2.1 2 0 0 2 2 2 1 BUD22 QRPTase_C PF01729.14 CBZ28055.1 - 0.0019 17.7 0.8 0.0042 16.6 0.5 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Daxx PF03344.10 CBZ28055.1 - 0.0026 16.3 24.7 0.0026 16.3 17.1 2.1 2 0 0 2 2 2 1 Daxx Family TFIIA PF03153.8 CBZ28055.1 - 0.0069 16.3 18.3 0.013 15.4 12.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Colicin_D PF11429.3 CBZ28055.1 - 0.07 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Colicin D PQQ_3 PF13570.1 CBZ28055.1 - 0.084 13.1 6.2 18 5.7 0.1 4.6 4 0 0 4 4 4 0 PQQ-like domain NOA36 PF06524.7 CBZ28055.1 - 0.82 8.8 14.6 1.4 8.1 10.1 1.3 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.6 CBZ28055.1 - 5.5 5.5 14.0 11 4.5 9.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2151 PF10221.4 CBZ28055.1 - 9.4 4.2 15.3 15 3.6 10.6 1.3 1 0 0 1 1 1 0 Cell cycle and development regulator DUF2749 PF10907.3 CBZ28055.1 - 9.9 6.1 14.2 0.16 11.8 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2749) Ribosomal_L29 PF00831.18 CBZ28056.1 - 1e-19 69.9 2.5 1e-19 69.9 1.7 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.8 CBZ28056.1 - 0.022 14.6 0.5 0.022 14.6 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Use1 PF09753.4 CBZ28056.1 - 0.13 11.6 6.1 0.15 11.4 4.2 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 Ribosomal_S9 PF00380.14 CBZ28056.1 - 0.81 9.9 5.6 1.3 9.2 3.9 1.5 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Ribosomal_L29 PF00831.18 CBZ28057.1 - 1e-19 69.9 2.5 1e-19 69.9 1.7 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.8 CBZ28057.1 - 0.022 14.6 0.5 0.022 14.6 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Use1 PF09753.4 CBZ28057.1 - 0.13 11.6 6.1 0.15 11.4 4.2 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 Ribosomal_S9 PF00380.14 CBZ28057.1 - 0.81 9.9 5.6 1.3 9.2 3.9 1.5 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Sec1 PF00995.18 CBZ28059.1 - 3.6e-93 313.1 0.0 4.1e-93 312.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HECT PF00632.20 CBZ28060.1 - 6.1e-30 104.4 0.0 1.1e-29 103.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CBZ28060.1 - 3.3e-14 53.0 0.0 1e-13 51.4 0.0 1.9 2 0 0 2 2 2 1 SPRY domain zf-RanBP PF00641.13 CBZ28060.1 - 8.7e-07 27.9 13.6 2.6e-05 23.2 1.8 2.8 1 1 1 2 2 2 2 Zn-finger in Ran binding protein and others fn3 PF00041.16 CBZ28061.1 - 1.4e-96 316.7 48.7 2.4e-05 24.3 0.3 38.1 42 3 0 42 42 42 21 Fibronectin type III domain Interfer-bind PF09294.5 CBZ28061.1 - 1.9e-14 53.5 8.9 4 7.5 0.0 14.9 16 0 0 16 16 16 2 Interferon-alpha/beta receptor, fibronectin type III Y_Y_Y PF07495.8 CBZ28061.1 - 0.0053 16.4 0.0 2.6 7.8 0.0 4.7 5 0 0 5 5 5 1 Y_Y_Y domain DUF295 PF03478.13 CBZ28061.1 - 0.0072 15.6 0.1 9.4 5.6 0.0 4.3 3 0 0 3 3 3 1 Protein of unknown function (DUF295) DUF2369 PF10179.4 CBZ28061.1 - 0.049 12.7 0.1 53 2.7 0.0 5.3 6 0 0 6 6 6 0 Uncharacterised conserved protein (DUF2369) DUF616 PF04765.8 CBZ28061.1 - 0.2 10.7 0.0 3 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF616) Spore_GerQ PF09671.5 CBZ28061.1 - 0.68 9.6 0.0 2.1 8.0 0.0 1.8 1 0 0 1 1 1 0 Spore coat protein (Spore_GerQ) zf-primase PF09329.6 CBZ28062.1 - 6e-11 41.7 0.6 1.3e-10 40.7 0.4 1.5 1 0 0 1 1 1 1 Primase zinc finger Mcm10 PF09332.6 CBZ28062.1 - 1.9e-07 30.7 3.6 4.1e-07 29.6 2.5 1.5 1 0 0 1 1 1 1 Mcm10 replication factor Tim17 PF02466.14 CBZ28063.1 - 1e-15 57.8 1.3 1.8e-15 57.1 0.7 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF1656 PF07869.7 CBZ28063.1 - 0.026 14.3 0.3 0.072 12.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DUF2984 PF11203.3 CBZ28064.1 - 0.24 11.5 0.1 0.24 11.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2984) DUF3772 PF12607.3 CBZ28064.1 - 1.1 8.9 4.9 1 9.0 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) BTB PF00651.26 CBZ28065.1 - 3.1e-10 39.9 0.1 0.0012 18.7 0.1 3.1 2 2 0 2 2 2 2 BTB/POZ domain JAB PF01398.16 CBZ28066.1 - 1.5e-17 63.3 0.4 4.4e-10 39.2 0.1 2.5 2 0 0 2 2 2 2 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CBZ28066.1 - 5.3e-10 38.7 0.3 4.6e-07 29.3 0.1 2.4 2 0 0 2 2 2 2 Prokaryotic homologs of the JAB domain Pkinase PF00069.20 CBZ28067.1 - 4.8e-42 143.9 0.0 6.4e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28067.1 - 9.2e-32 110.1 0.0 1.3e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28067.1 - 0.0023 16.9 0.1 0.0072 15.3 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBZ28067.1 - 0.0026 16.8 0.1 0.0048 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Telethonin PF09470.5 CBZ28068.1 - 0.0018 17.7 0.1 0.0025 17.2 0.1 1.1 1 0 0 1 1 1 1 Telethonin protein DUF2513 PF10711.4 CBZ28068.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) RRM_1 PF00076.17 CBZ28068.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_Tnp_IS1 PF03811.8 CBZ28070.1 - 0.086 12.3 1.6 0.086 12.3 1.1 2.7 3 0 0 3 3 3 0 InsA N-terminal domain Mu-like_Com PF10122.4 CBZ28070.1 - 0.5 9.4 4.4 0.75 8.9 0.2 2.5 3 0 0 3 3 3 0 Mu-like prophage protein Com Opiods_neuropep PF01160.13 CBZ28070.1 - 0.77 9.5 7.1 4.1 7.2 0.7 2.9 2 2 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide DZR PF12773.2 CBZ28070.1 - 1 9.1 11.6 14 5.5 2.0 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf-CHY PF05495.7 CBZ28070.1 - 1.2 9.3 7.9 22 5.2 0.8 2.5 1 1 1 2 2 2 0 CHY zinc finger RNHCP PF12647.2 CBZ28070.1 - 3.7 7.4 9.0 2.6 7.9 2.1 2.7 1 1 2 3 3 3 0 RNHCP domain Whib PF02467.11 CBZ28070.1 - 8.6 6.7 7.6 3.6 7.9 0.9 2.6 1 1 1 2 2 2 0 Transcription factor WhiB CDP-OH_P_transf PF01066.16 CBZ28071.1 - 6.5e-15 55.2 17.1 3e-14 53.1 11.8 2.1 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase IBV_3A PF03617.8 CBZ28071.1 - 0.042 13.6 0.3 0.12 12.1 0.2 1.7 1 0 0 1 1 1 0 IBV 3A protein CHCH PF06747.8 CBZ28074.1 - 0.00073 19.3 10.5 0.2 11.6 3.1 2.5 2 0 0 2 2 2 2 CHCH domain DUF1903 PF08991.5 CBZ28074.1 - 0.0027 17.8 6.1 0.089 12.9 0.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1903) NHR2 PF08788.6 CBZ28074.1 - 0.21 11.1 4.6 0.27 10.7 2.9 1.5 1 1 0 1 1 1 0 NHR2 domain like COX6B PF02297.12 CBZ28074.1 - 5.6 7.0 10.9 0.74 9.8 4.6 1.9 2 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.20 CBZ28075.1 - 6.3e-49 166.4 0.0 7.8e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28075.1 - 4.3e-28 98.0 0.0 6.2e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.16 CBZ28075.1 - 1.1e-08 34.8 14.6 2.6e-08 33.6 10.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.18 CBZ28075.1 - 0.0031 17.2 0.0 0.014 15.1 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBZ28075.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 CBZ28075.1 - 0.049 12.9 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 CBZ28075.1 - 0.26 10.0 0.0 0.41 9.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DnaJ PF00226.26 CBZ28076.1 - 1.8e-05 24.3 0.0 5.9e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain CDC27 PF09507.5 CBZ28076.1 - 8.7 5.4 38.4 3.1 6.9 13.5 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Metallophos PF00149.23 CBZ28077.1 - 3.1e-32 111.5 0.0 4.4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPR_3 PF13812.1 CBZ28078.1 - 0.00076 19.5 0.1 0.016 15.4 0.1 3.2 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.15 CBZ28078.1 - 0.0025 17.6 0.2 0.98 9.5 0.0 3.2 3 0 0 3 3 3 2 PPR repeat SET PF00856.23 CBZ28080.1 - 9.2e-13 48.8 0.0 6.6e-11 42.7 0.0 2.4 1 1 0 1 1 1 1 SET domain Dala_Dala_lig_C PF07478.8 CBZ28080.1 - 1.1e-12 47.8 0.0 1.7e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_4 PF13535.1 CBZ28080.1 - 2e-10 40.7 0.0 5.8e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 CBZ28080.1 - 0.00071 18.9 0.0 0.0012 18.2 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Pkinase PF00069.20 CBZ28081.1 - 7.9e-49 166.1 0.0 1e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28081.1 - 3.7e-34 117.9 0.0 4.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SYCE1 PF15233.1 CBZ28082.1 - 1.9 8.4 7.4 5.5 6.9 5.2 1.8 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 PqiA PF04403.8 CBZ28083.1 - 1.5e-17 63.5 23.9 3.8e-16 59.0 6.7 3.5 2 1 1 3 3 3 3 Paraquat-inducible protein A FAD_binding_3 PF01494.14 CBZ28085.1 - 1.7e-11 43.7 0.0 3.3e-09 36.2 0.0 2.8 2 2 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 CBZ28085.1 - 7.4e-07 29.1 0.0 1.9e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CBZ28085.1 - 1.4e-05 24.1 0.0 0.00016 20.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CBZ28085.1 - 0.00014 22.1 0.0 0.00032 21.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CBZ28085.1 - 0.00025 20.0 0.1 0.00047 19.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CBZ28085.1 - 0.0051 16.7 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CBZ28085.1 - 0.021 13.7 0.3 0.042 12.7 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 CBZ28085.1 - 0.026 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 CBZ28085.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-CSL PF05207.8 CBZ28087.1 - 3.1e-17 61.8 0.4 4e-17 61.4 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger DUF2387 PF09526.5 CBZ28087.1 - 0.09 12.7 0.1 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) Bacillus_HBL PF05791.6 CBZ28088.1 - 0.026 13.8 0.6 0.045 13.1 0.4 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 CBZ28088.1 - 0.042 12.3 0.1 0.066 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.1 CBZ28088.1 - 0.34 10.8 2.6 0.21 11.5 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) HECT PF00632.20 CBZ28089.1 - 6.4e-07 28.8 0.0 0.001 18.2 0.0 3.0 4 1 0 5 5 5 2 HECT-domain (ubiquitin-transferase) Mito_fiss_reg PF05308.6 CBZ28089.1 - 4.4 6.5 9.2 0.26 10.6 0.6 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Filament PF00038.16 CBZ28090.1 - 1.4 8.2 84.0 4.4 6.6 0.4 6.3 1 1 3 4 4 4 0 Intermediate filament protein ABC_membrane PF00664.18 CBZ28091.1 - 2.2e-85 286.4 31.3 1.2e-45 156.1 8.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ28091.1 - 2.1e-69 232.1 0.1 1.7e-35 122.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CBZ28091.1 - 1.5e-12 47.2 1.1 1.8e-06 27.3 0.0 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBZ28091.1 - 2.1e-07 30.3 0.1 0.0068 15.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_21 PF13304.1 CBZ28091.1 - 1.1e-06 28.8 0.0 0.39 10.6 0.0 4.2 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.1 CBZ28091.1 - 4.5e-06 26.0 0.6 0.05 13.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 CBZ28091.1 - 1.3e-05 24.0 0.1 0.0015 17.1 0.0 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_17 PF13207.1 CBZ28091.1 - 1.6e-05 25.7 0.0 0.22 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 CBZ28091.1 - 0.00027 21.1 2.5 1 9.5 0.3 4.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CBZ28091.1 - 0.00052 19.1 0.1 0.068 12.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 CBZ28091.1 - 0.001 19.2 2.8 0.69 10.0 0.0 3.9 2 2 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBZ28091.1 - 0.0011 19.3 0.5 1.8 8.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CBZ28091.1 - 0.0022 18.3 0.0 1 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CBZ28091.1 - 0.0026 17.1 0.3 9.2 5.6 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.9 CBZ28091.1 - 0.0035 17.0 0.0 0.54 9.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CBZ28091.1 - 0.0039 16.9 4.2 2 8.2 0.0 4.4 5 0 0 5 5 3 1 Part of AAA domain SbcCD_C PF13558.1 CBZ28091.1 - 0.0048 16.7 5.1 2.1 8.3 0.4 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CBZ28091.1 - 0.0055 16.5 1.4 1.5 8.5 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 CBZ28091.1 - 0.0062 16.6 0.3 6.1 7.0 0.1 3.1 2 0 0 2 2 2 0 RNA helicase G-alpha PF00503.15 CBZ28091.1 - 0.007 15.1 0.1 0.38 9.3 0.0 2.1 2 0 0 2 2 2 1 G-protein alpha subunit ATP-synt_ab PF00006.20 CBZ28091.1 - 0.011 15.2 0.4 4.2 6.8 0.0 2.8 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.1 CBZ28091.1 - 0.014 15.3 0.1 5.7 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.13 CBZ28091.1 - 0.016 14.7 0.1 9.6 5.6 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 CBZ28091.1 - 0.022 14.6 0.0 7.2 6.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 CBZ28091.1 - 0.022 15.2 0.1 11 6.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Rad17 PF03215.10 CBZ28091.1 - 0.032 12.9 0.1 0.53 8.9 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 CBZ28091.1 - 0.061 13.2 0.6 4.5 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Neurensin PF14927.1 CBZ28091.1 - 0.41 10.0 3.5 7.6 5.9 0.1 3.3 3 0 0 3 3 3 0 Neurensin Abi PF02517.11 CBZ28093.1 - 7.1e-19 67.7 1.2 9.4e-19 67.3 0.1 1.7 2 0 0 2 2 2 1 CAAX protease self-immunity SPC12 PF06645.8 CBZ28093.1 - 0.082 12.7 0.8 0.36 10.6 0.1 2.1 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Glucosamine_iso PF01182.15 CBZ28094.1 - 1.1e-45 155.7 0.1 1.3e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase AA_kinase PF00696.23 CBZ28095.1 - 8.9e-38 130.1 0.3 1e-37 130.0 0.2 1.0 1 0 0 1 1 1 1 Amino acid kinase family TPR_19 PF14559.1 CBZ28096.1 - 0.00017 21.8 2.4 0.43 10.9 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ28096.1 - 0.0003 21.1 3.1 0.39 11.4 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ28096.1 - 0.00053 19.6 3.1 0.68 9.9 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 CBZ28096.1 - 0.0012 18.9 0.3 0.064 13.3 0.0 3.5 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ28096.1 - 0.035 14.8 5.9 5.7 7.7 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ28096.1 - 0.037 14.4 3.6 1.4 9.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ28096.1 - 0.055 13.4 0.2 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Thioredoxin PF00085.15 CBZ28096.1 - 0.096 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Meckelin PF09773.4 CBZ28097.1 - 0 1118.8 7.4 0 1118.6 5.1 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) MSC PF09402.5 CBZ28097.1 - 0.028 13.1 0.2 0.075 11.7 0.1 1.6 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain TGT PF01702.13 CBZ28098.1 - 3.1e-33 115.0 0.0 5.3e-33 114.2 0.0 1.3 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Peptidase_M48 PF01435.13 CBZ28099.1 - 1.8e-41 142.1 0.0 2.9e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 CBZ28099.1 - 0.046 12.7 0.6 0.082 11.8 0.1 1.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 DEAD PF00270.24 CBZ28100.1 - 4.6e-37 127.0 0.2 8.1e-37 126.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ28100.1 - 9.5e-22 76.6 0.0 3.7e-21 74.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBZ28100.1 - 1.1e-10 40.8 0.1 3.1e-10 39.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBZ28100.1 - 7.6e-05 22.6 0.0 0.00023 21.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBZ28100.1 - 0.014 15.5 1.5 0.65 10.1 0.5 3.2 2 1 0 2 2 2 0 AAA domain p450 PF00067.17 CBZ28104.1 - 2.7e-54 184.4 0.0 3.6e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tom5 PF10642.4 CBZ28104.1 - 0.03 13.9 0.7 0.075 12.6 0.5 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Pkinase PF00069.20 CBZ28105.1 - 2.5e-64 216.9 0.0 3.3e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28105.1 - 4.7e-27 94.6 0.0 8e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RINGv PF12906.2 CBZ28107.1 - 7e-10 38.7 11.9 1.3e-09 37.8 8.2 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_4 PF14570.1 CBZ28107.1 - 0.83 9.2 9.8 2.3 7.8 6.8 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain WW PF00397.21 CBZ28108.1 - 1.1e-10 41.2 2.0 1.1e-10 41.2 1.4 1.8 2 0 0 2 2 2 1 WW domain zf-CCCH PF00642.19 CBZ28108.1 - 7.6e-07 28.6 0.3 1.1e-06 28.1 0.2 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3251 PF11622.3 CBZ28109.1 - 0.042 13.2 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3251) Peptidase_S26 PF10502.4 CBZ28109.1 - 0.08 12.4 0.1 0.26 10.8 0.0 1.8 2 1 0 2 2 2 0 Signal peptidase, peptidase S26 zf-CCCH PF00642.19 CBZ28110.1 - 0.0023 17.5 0.4 0.0034 17.0 0.2 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CDC27 PF09507.5 CBZ28110.1 - 0.0031 16.7 1.3 0.0037 16.5 0.9 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 SET PF00856.23 CBZ28111.1 - 3.8e-12 46.7 0.3 1e-11 45.4 0.2 1.8 1 1 0 1 1 1 1 SET domain OSTMP1 PF09777.4 CBZ28111.1 - 0.049 12.7 0.6 0.071 12.2 0.4 1.2 1 0 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor SIT PF15330.1 CBZ28113.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Proteasome PF00227.21 CBZ28114.1 - 4.7e-44 149.9 0.1 6.1e-44 149.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ28114.1 - 9.9e-10 37.5 0.1 9.9e-10 37.5 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature VIT1 PF01988.14 CBZ28116.1 - 9.7e-62 208.2 4.5 1.2e-61 207.9 3.1 1.1 1 0 0 1 1 1 1 VIT family XPG_I PF00867.13 CBZ28120.1 - 2.5e-30 104.3 0.0 4.6e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CBZ28120.1 - 1.1e-26 93.0 0.0 2.3e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 CBZ28120.1 - 1.3e-06 28.6 0.0 8.2e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Sigma70_r1_1 PF03979.9 CBZ28120.1 - 0.016 15.1 0.1 0.057 13.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 XPG_I_2 PF12813.2 CBZ28120.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing 5_3_exonuc_N PF02739.11 CBZ28120.1 - 0.1 12.0 0.0 0.43 9.9 0.0 1.9 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain zf-H2C2_5 PF13909.1 CBZ28122.1 - 0.15 12.3 0.5 0.37 11.1 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF4544 PF15077.1 CBZ28122.1 - 0.35 10.3 12.4 0.14 11.6 2.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4544) PP-binding PF00550.20 CBZ28124.1 - 6.3e-10 39.1 0.2 9.1e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CBZ28124.1 - 0.058 13.4 0.3 0.077 13.0 0.2 1.3 1 0 0 1 1 1 0 Acyl-carrier MM_CoA_mutase PF01642.17 CBZ28125.1 - 3.6e-228 757.8 1.1 4.3e-228 757.6 0.8 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 CBZ28125.1 - 1.1e-10 41.4 0.1 3.2e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 B12 binding domain HisG_C PF08029.6 CBZ28125.1 - 0.01 15.7 0.0 0.033 14.1 0.0 1.9 1 0 0 1 1 1 1 HisG, C-terminal domain TIP120 PF08623.5 CBZ28126.1 - 4.8e-09 36.0 0.4 6.7e-08 32.3 0.0 2.6 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) RRM_1 PF00076.17 CBZ28130.1 - 9.5e-14 50.7 0.0 2.9e-07 30.0 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ28130.1 - 3e-12 46.3 0.0 2.5e-08 33.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ28130.1 - 3.6e-07 29.9 0.0 1.6e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 CBZ28131.1 - 3e-36 124.5 0.0 2.7e-35 121.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ28131.1 - 9.5e-11 42.0 0.9 0.0005 20.0 0.1 4.0 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 CBZ28131.1 - 0.00033 21.4 0.0 0.00088 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ28131.1 - 0.0012 18.5 0.0 0.0087 15.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CBZ28131.1 - 0.0013 18.6 0.0 0.028 14.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 CBZ28131.1 - 0.0039 16.1 0.0 1.7 7.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RNA_helicase PF00910.17 CBZ28131.1 - 0.0051 16.9 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.10 CBZ28131.1 - 0.0075 14.9 0.0 0.026 13.2 0.0 1.7 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 CBZ28131.1 - 0.012 15.3 0.0 0.66 9.6 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase AAA_22 PF13401.1 CBZ28131.1 - 0.035 14.2 0.0 1.4 9.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.7 CBZ28131.1 - 0.11 11.4 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Herpes_UL49_5 PF05702.6 CBZ28132.1 - 0.02 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Nup96 PF12110.3 CBZ28133.1 - 3.3e-51 174.1 0.0 6.3e-51 173.2 0.0 1.5 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.9 CBZ28133.1 - 4.7e-21 75.0 0.0 9.2e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase APG9 PF04109.11 CBZ28134.1 - 3.2e-43 148.0 0.0 1.4e-42 145.9 0.0 1.8 1 1 0 1 1 1 1 Autophagy protein Apg9 DnaJ PF00226.26 CBZ28136.1 - 4.4e-25 87.1 0.6 7.4e-25 86.4 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Tic20 PF09685.5 CBZ28136.1 - 0.11 12.5 1.8 0.2 11.6 1.2 1.4 1 0 0 1 1 1 0 Tic20-like protein PfkB PF00294.19 CBZ28137.1 - 1.9e-64 217.7 0.1 2.3e-64 217.4 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CBZ28137.1 - 2.9e-10 39.7 0.0 4.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Mur_ligase PF01225.20 CBZ28137.1 - 0.011 15.8 0.1 0.085 12.9 0.0 2.5 2 2 0 2 2 2 0 Mur ligase family, catalytic domain Vps53_N PF04100.7 CBZ28138.1 - 0.0064 15.3 0.9 0.0095 14.7 0.6 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal Brix PF04427.13 CBZ28140.1 - 6.6e-44 149.8 0.1 1.1e-43 149.0 0.1 1.4 1 0 0 1 1 1 1 Brix domain Vasohibin PF14822.1 CBZ28141.1 - 1.1e-48 165.5 0.0 1.6e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 Vasohibin ABC_membrane_2 PF06472.10 CBZ28142.1 - 4.6e-27 94.8 0.4 8.7e-27 93.9 0.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CBZ28142.1 - 2.9e-15 56.7 0.0 6.9e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CBZ28142.1 - 3.3e-08 33.0 0.0 4.4e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 CBZ28142.1 - 3e-05 23.7 0.0 8e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 NACHT domain AAA_21 PF13304.1 CBZ28142.1 - 0.00017 21.6 0.0 0.0025 17.8 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CBZ28142.1 - 0.0018 18.6 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ28142.1 - 0.0023 18.0 0.1 0.76 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ28142.1 - 0.0024 17.9 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 CBZ28142.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 CBZ28142.1 - 0.012 16.0 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Sigma54_activ_2 PF14532.1 CBZ28142.1 - 0.013 15.5 0.0 0.38 10.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_15 PF13175.1 CBZ28142.1 - 0.03 13.3 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SH3_3 PF08239.6 CBZ28143.1 - 0.077 13.2 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Bacterial SH3 domain Peptidase_C2 PF00648.16 CBZ28144.1 - 8.9e-50 169.3 0.0 1.6e-25 89.7 0.0 2.4 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.17 CBZ28144.1 - 4.6e-19 68.5 0.0 7.5e-10 38.6 0.0 3.1 3 0 0 3 3 3 2 Calpain large subunit, domain III DUF372 PF04036.7 CBZ28144.1 - 0.0019 17.6 0.1 0.01 15.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF372) phage_tail_N PF08400.5 CBZ28144.1 - 0.13 11.9 0.0 15 5.2 0.0 2.8 2 0 0 2 2 2 0 Prophage tail fibre N-terminal TRF PF08558.5 CBZ28144.1 - 2.2 7.5 3.5 11 5.2 0.4 2.4 2 0 0 2 2 2 0 Telomere repeat binding factor (TRF) DUF3563 PF12086.3 CBZ28144.1 - 2.4 7.9 18.4 42 3.9 0.1 6.0 6 0 0 6 6 6 0 Protein of unknown function (DUF3563) Peptidase_C2 PF00648.16 CBZ28146.1 - 1.1e-66 224.9 0.0 3.8e-25 88.4 0.0 3.4 3 0 0 3 3 3 3 Calpain family cysteine protease Calpain_III PF01067.17 CBZ28146.1 - 1.1e-22 80.2 0.0 5e-09 35.9 0.0 3.9 3 0 0 3 3 3 3 Calpain large subunit, domain III Radial_spoke_3 PF06098.6 CBZ28147.1 - 3.9e-118 393.6 28.1 4.6e-118 393.4 19.5 1.0 1 0 0 1 1 1 1 Radial spoke protein 3 eIF3_p135 PF12807.2 CBZ28147.1 - 0.13 12.1 6.8 0.025 14.5 2.2 1.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 Amino_oxidase PF01593.19 CBZ28147.1 - 2.5 7.0 5.5 7 5.6 3.8 1.8 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase Amastin PF07344.6 CBZ28149.1 - 2.2e-09 37.1 8.9 2.2e-09 37.1 6.2 1.9 1 1 1 2 2 2 1 Amastin surface glycoprotein Rep_fac_C PF08542.6 CBZ28150.1 - 5.3e-16 58.3 0.1 4.1e-15 55.5 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBZ28150.1 - 1.9e-12 47.1 0.0 9.9e-12 44.8 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CBZ28150.1 - 3e-11 43.6 0.1 1.1e-10 41.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBZ28150.1 - 1.9e-09 36.7 0.0 6.4e-07 28.4 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CBZ28150.1 - 1.1e-07 32.0 0.0 3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CBZ28150.1 - 2.2e-05 23.7 0.1 0.00096 18.3 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBZ28150.1 - 5e-05 23.3 0.7 0.0015 18.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CBZ28150.1 - 5.2e-05 22.9 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CBZ28150.1 - 7.1e-05 21.9 0.0 0.00019 20.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DNA_pol3_delta PF06144.8 CBZ28150.1 - 7.4e-05 22.3 0.2 0.0002 20.9 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_30 PF13604.1 CBZ28150.1 - 0.00077 19.0 0.1 0.0027 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CBZ28150.1 - 0.0012 18.3 0.0 0.0029 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_14 PF13173.1 CBZ28150.1 - 0.0015 18.3 0.0 0.0041 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CBZ28150.1 - 0.0022 17.5 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_25 PF13481.1 CBZ28150.1 - 0.0027 17.1 0.7 0.0096 15.3 0.1 2.1 2 2 0 2 2 2 1 AAA domain DUF2075 PF09848.4 CBZ28150.1 - 0.0086 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 CBZ28150.1 - 0.012 15.3 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CBZ28150.1 - 0.019 14.5 0.3 0.048 13.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBZ28150.1 - 0.024 14.8 0.0 0.074 13.2 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.1 CBZ28150.1 - 0.034 14.0 0.3 0.11 12.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.1 CBZ28150.1 - 0.035 13.6 0.0 0.054 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBZ28150.1 - 0.038 13.4 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 CBZ28150.1 - 0.041 12.5 0.2 0.91 8.1 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus AAA_18 PF13238.1 CBZ28150.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CBZ28150.1 - 0.094 12.3 0.0 19 4.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 CBZ28151.1 - 3.4e-63 213.2 0.0 3.9e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28151.1 - 7.5e-27 94.0 0.0 9.9e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ28151.1 - 0.033 13.9 0.1 0.11 12.2 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBZ28151.1 - 0.11 11.2 0.0 0.46 9.2 0.0 1.9 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase zf-RING_2 PF13639.1 CBZ28152.1 - 2.5e-10 39.9 7.0 2.5e-10 39.9 4.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ28152.1 - 3.9e-07 29.6 7.2 3.9e-07 29.6 5.0 2.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ28152.1 - 6e-07 29.0 6.7 6e-07 29.0 4.7 2.8 2 1 1 3 3 2 1 zinc-RING finger domain PHD PF00628.24 CBZ28152.1 - 2.5e-06 27.0 5.5 2.5e-06 27.0 3.8 2.6 2 1 0 2 2 1 1 PHD-finger zf-rbx1 PF12678.2 CBZ28152.1 - 5.5e-06 26.3 2.4 5.5e-06 26.3 1.7 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CBZ28152.1 - 6.8e-06 25.6 5.1 6.8e-06 25.6 3.5 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ28152.1 - 0.00011 22.1 8.4 0.00011 22.1 5.8 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CBZ28152.1 - 0.0017 18.0 3.9 0.0054 16.4 2.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBZ28152.1 - 0.012 15.5 3.5 0.012 15.5 2.4 2.7 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CBZ28152.1 - 0.02 14.7 1.8 0.02 14.7 1.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger CbiM PF01891.11 CBZ28152.1 - 0.029 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region C1_1 PF00130.17 CBZ28152.1 - 0.035 13.8 1.1 0.035 13.8 0.8 2.7 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_6 PF14835.1 CBZ28152.1 - 0.18 11.5 3.1 0.57 10.0 2.1 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 CBZ28152.1 - 0.78 9.3 6.0 0.43 10.1 2.5 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-UDP PF14569.1 CBZ28152.1 - 1.1 9.0 8.5 0.06 13.0 1.2 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING_4 PF14570.1 CBZ28152.1 - 8.5 6.0 20.1 0.02 14.4 4.6 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CBZ28152.1 - 10 6.2 17.3 3.2 7.7 2.0 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain WD40 PF00400.27 CBZ28153.1 - 1.3e-11 43.8 1.4 0.00037 20.2 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat LisH PF08513.6 CBZ28153.1 - 0.0011 18.6 0.1 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 LisH PQQ PF01011.16 CBZ28153.1 - 0.064 12.8 0.1 13 5.5 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat DUF4471 PF14740.1 CBZ28154.1 - 2.4e-87 292.8 0.0 3.5e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) DUF4470 PF14737.1 CBZ28154.1 - 3.1e-21 74.9 0.0 7.5e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) MRP-S28 PF10213.4 CBZ28158.1 - 0.00018 21.5 0.1 0.00044 20.3 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein XylR_N PF06505.6 CBZ28158.1 - 0.034 13.5 0.1 0.097 12.1 0.0 1.7 1 0 0 1 1 1 0 Activator of aromatic catabolism DUF3408 PF11888.3 CBZ28159.1 - 0.024 14.5 0.1 0.046 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Snapin_Pallidin PF14712.1 CBZ28159.1 - 0.073 13.3 0.2 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Snapin/Pallidin ALIX_LYPXL_bnd PF13949.1 CBZ28159.1 - 0.094 11.6 1.0 0.48 9.3 0.1 2.1 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV PAS_2 PF08446.6 CBZ28160.1 - 0.1 13.0 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 PAS fold DUF4066 PF13278.1 CBZ28160.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase Mucin PF01456.12 CBZ28161.1 - 7.9e-07 28.9 44.6 2.2e-06 27.4 30.9 1.8 1 0 0 1 1 1 1 Mucin-like glycoprotein MGC-24 PF05283.6 CBZ28161.1 - 0.0037 17.0 20.4 0.0037 17.0 14.1 2.4 3 0 0 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24) ABC2_membrane_3 PF12698.2 CBZ28161.1 - 0.078 11.9 2.4 0.072 12.1 0.6 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein AJAP1_PANP_C PF15298.1 CBZ28161.1 - 0.099 12.5 24.5 0.032 14.1 14.6 1.9 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Aa_trans PF01490.13 CBZ28162.1 - 6.4e-55 186.2 33.2 8e-55 185.9 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein VPEP PF07589.6 CBZ28162.1 - 5.6 7.0 5.9 5.6 7.0 0.3 3.2 2 0 0 2 2 2 0 PEP-CTERM motif Aa_trans PF01490.13 CBZ28163.1 - 5.5e-46 156.8 35.9 6.9e-46 156.5 24.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ28163.1 - 1.7e-09 36.9 20.0 1.7e-09 36.9 13.9 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2207 PF09972.4 CBZ28163.1 - 0.046 12.2 0.1 0.046 12.2 0.1 2.2 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF843 PF05814.6 CBZ28163.1 - 1.9 8.3 6.0 0.63 9.8 0.5 2.4 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) LRR_4 PF12799.2 CBZ28164.1 - 0.00013 21.4 0.4 0.00039 19.9 0.0 2.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBZ28164.1 - 0.0034 17.3 0.4 4.7 7.5 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeat LRR_7 PF13504.1 CBZ28164.1 - 0.043 13.9 0.1 1.6 9.2 0.0 3.3 3 0 0 3 3 3 0 Leucine rich repeat LRR_8 PF13855.1 CBZ28164.1 - 0.21 11.3 2.7 0.3 10.8 0.1 2.4 2 1 1 3 3 3 0 Leucine rich repeat UBA PF00627.26 CBZ28167.1 - 8.5e-11 41.3 0.3 2.3e-10 39.9 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 CBZ28167.1 - 0.036 13.6 0.1 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain NAD_binding_1 PF00175.16 CBZ28168.1 - 3.8e-17 62.8 0.0 6.4e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBZ28168.1 - 1.8e-13 50.4 0.0 2.7e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CBZ28168.1 - 0.00023 21.0 0.0 0.00084 19.2 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain CCT_2 PF09425.5 CBZ28168.1 - 0.13 11.8 0.2 0.31 10.6 0.1 1.7 1 0 0 1 1 1 0 Divergent CCT motif Oxidored_q6 PF01058.17 CBZ28169.1 - 2.5e-19 69.2 0.1 3.2e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Dabb PF07876.7 CBZ28170.1 - 7.2e-12 45.5 0.0 8.9e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Dabb PF07876.7 CBZ28171.1 - 1.5e-10 41.3 0.0 1.9e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ras PF00071.17 CBZ28172.1 - 4.6e-64 214.6 0.6 5.3e-64 214.4 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ28172.1 - 8.9e-22 77.8 0.1 1.3e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ28172.1 - 4.3e-16 58.6 0.1 5.2e-16 58.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ28172.1 - 7.1e-08 31.8 0.1 8.4e-08 31.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ28172.1 - 6.8e-06 25.6 0.3 1.3e-05 24.7 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CBZ28172.1 - 3.2e-05 23.2 0.1 4.6e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBZ28172.1 - 0.00022 21.1 0.1 0.00041 20.2 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ28172.1 - 0.00051 19.3 0.1 0.0027 17.0 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 CBZ28172.1 - 0.002 18.2 0.0 0.0037 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CBZ28172.1 - 0.0046 17.1 0.1 0.48 10.6 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CBZ28172.1 - 0.0061 15.7 0.1 0.018 14.1 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CBZ28172.1 - 0.017 15.4 0.2 0.1 12.8 0.1 1.9 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 CBZ28172.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 CBZ28172.1 - 0.019 13.6 5.4 0.098 11.3 0.8 2.6 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.1 CBZ28172.1 - 0.046 13.2 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 CBZ28172.1 - 0.13 11.9 0.1 0.25 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Pkinase PF00069.20 CBZ28173.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF607 PF04678.8 CBZ28174.1 - 5.9e-53 179.4 0.1 9.3e-53 178.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF607 Glyoxalase_4 PF13669.1 CBZ28174.1 - 0.097 12.6 0.1 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MatE PF01554.13 CBZ28175.1 - 4.8e-34 117.3 21.7 1.5e-19 70.2 5.6 2.5 2 0 0 2 2 2 2 MatE FAM176 PF14851.1 CBZ28175.1 - 0.033 13.8 0.1 0.076 12.7 0.1 1.5 1 0 0 1 1 1 0 FAM176 family LRR_6 PF13516.1 CBZ28176.1 - 1.2e-05 24.8 2.0 0.11 12.5 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 CBZ28176.1 - 0.061 12.9 4.2 1.7 8.3 0.4 3.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ28176.1 - 0.091 12.5 1.0 1.2 8.9 0.9 2.4 2 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 CBZ28176.1 - 1.4 9.2 5.8 39 4.8 0.2 4.1 4 1 0 4 4 4 0 Leucine Rich Repeat Glutaredoxin PF00462.19 CBZ28177.1 - 1.2e-15 57.2 0.1 1.7e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CBZ28177.1 - 2e-05 24.2 0.1 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 CBZ28177.1 - 0.0013 18.9 0.3 0.0035 17.5 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.15 CBZ28177.1 - 0.0029 17.1 0.3 0.16 11.5 0.2 2.1 1 1 1 2 2 2 1 DSBA-like thioredoxin domain GST_N_3 PF13417.1 CBZ28177.1 - 0.0032 17.6 0.0 0.0043 17.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.1 CBZ28177.1 - 0.004 17.1 0.2 1.1 9.2 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin DUF836 PF05768.9 CBZ28177.1 - 0.0042 17.2 0.1 0.0049 17.0 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Redoxin PF08534.5 CBZ28177.1 - 0.085 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Redoxin DUF929 PF06053.6 CBZ28177.1 - 0.29 10.2 1.2 0.65 9.0 0.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF929) Beta_helix PF13229.1 CBZ28178.1 - 1.5e-93 310.7 130.1 6.7e-15 55.1 7.6 17.2 9 5 8 17 17 17 15 Right handed beta helix region NosD PF05048.8 CBZ28178.1 - 2.4e-77 259.2 50.2 1.8e-11 43.6 4.1 15.4 9 5 6 15 15 15 11 Periplasmic copper-binding protein (NosD) FliJ PF02050.11 CBZ28178.1 - 0.029 14.4 0.2 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein End3 PF12761.2 CBZ28178.1 - 0.21 11.1 0.1 0.42 10.2 0.1 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DMAP1 PF05499.7 CBZ28178.1 - 0.55 9.7 0.0 1.2 8.6 0.0 1.4 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF2020 PF09449.5 CBZ28181.1 - 0.068 12.8 0.5 0.13 11.9 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) WD40 PF00400.27 CBZ28182.1 - 8.2e-07 28.6 15.2 5.2e-06 26.1 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1126 PF06565.7 CBZ28183.1 - 5.1e-44 147.4 0.1 8.2e-14 50.7 0.0 3.7 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) EF-hand_7 PF13499.1 CBZ28183.1 - 3.2e-09 36.8 0.1 6.6e-08 32.5 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CBZ28183.1 - 1.1e-06 28.1 1.4 0.0077 15.8 0.0 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ28183.1 - 0.00028 19.9 0.4 12 5.4 0.0 4.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CBZ28183.1 - 0.015 15.0 0.2 14 5.8 0.1 4.1 4 0 0 4 4 4 0 EF-hand domain DUF1456 PF07308.8 CBZ28183.1 - 0.089 12.8 0.1 7.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) E1_dh PF00676.15 CBZ28185.1 - 4.6e-54 183.1 0.0 7.1e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.19 CBZ28185.1 - 3e-47 160.3 0.0 5.2e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PIP5K PF01504.13 CBZ28186.1 - 1.7e-60 204.2 0.0 2.9e-60 203.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.16 CBZ28186.1 - 1.7e-16 59.8 5.2 3.5e-16 58.8 3.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 CBZ28186.1 - 0.035 13.9 3.7 0.095 12.5 2.6 1.7 1 0 0 1 1 1 0 IBR domain C1_4 PF07975.7 CBZ28186.1 - 0.63 10.0 7.9 1.6 8.7 5.5 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain HypA PF01155.14 CBZ28186.1 - 6.6 6.4 7.2 1.7 8.3 1.5 2.5 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family DUF778 PF05608.7 CBZ28187.1 - 2.3e-42 144.1 0.2 2.7e-42 143.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF778) GATase_4 PF13230.1 CBZ28187.1 - 0.062 11.9 0.1 0.08 11.6 0.1 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II DUF4105 PF13387.1 CBZ28187.1 - 0.07 12.2 0.0 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) Pep3_Vps18 PF05131.9 CBZ28188.1 - 4.5e-09 35.8 0.0 2.5e-06 26.9 0.0 2.8 2 0 0 2 2 2 2 Pep3/Vps18/deep orange family Clathrin PF00637.15 CBZ28188.1 - 6.7e-07 28.9 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_2 PF10367.4 CBZ28188.1 - 1.8e-05 24.8 0.2 3.8e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 CBZ28188.1 - 0.0021 18.0 0.5 0.0097 15.9 0.4 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Clathrin_H_link PF13838.1 CBZ28188.1 - 0.0061 16.4 0.0 0.021 14.7 0.0 1.9 2 0 0 2 2 2 1 Clathrin-H-link zf-RING_5 PF14634.1 CBZ28188.1 - 5.5 6.8 11.0 0.073 12.8 1.9 2.3 2 1 0 2 2 2 0 zinc-RING finger domain DUF1295 PF06966.7 CBZ28189.1 - 1.2e-27 96.7 15.4 2.5e-27 95.6 10.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Cation_ATPase_C PF00689.16 CBZ28189.1 - 3.2 7.2 15.2 0.26 10.8 0.7 2.8 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Acyl-CoA_dh_1 PF00441.19 CBZ28190.1 - 4.5e-40 137.1 0.7 9e-40 136.2 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBZ28190.1 - 2.7e-27 95.5 0.0 6.6e-27 94.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 CBZ28190.1 - 7.1e-19 67.0 0.1 7.1e-19 67.0 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 CBZ28190.1 - 4.2e-18 65.8 0.1 9.3e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 CBZ28190.1 - 0.089 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal XRN_N PF03159.13 CBZ28191.1 - 8.6e-20 71.1 0.0 1.4e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XPG_N PF00752.12 CBZ28191.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 XPG N-terminal domain ABC2_membrane_3 PF12698.2 CBZ28194.1 - 1.1e-60 205.4 49.7 2.8e-39 135.1 11.7 3.2 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.22 CBZ28194.1 - 7.2e-53 178.5 0.0 8.2e-28 97.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBZ28194.1 - 2.3e-16 60.6 0.0 1.6e-06 28.3 0.0 4.2 3 1 0 3 3 3 3 AAA domain AAA_15 PF13175.1 CBZ28194.1 - 3.7e-06 26.2 0.0 0.48 9.4 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 CBZ28194.1 - 3.5e-05 23.2 0.2 0.035 13.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 CBZ28194.1 - 9.8e-05 22.2 0.0 0.076 12.9 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 CBZ28194.1 - 0.00011 22.5 2.1 0.16 12.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 CBZ28194.1 - 0.00024 20.3 0.0 4.6 6.4 0.0 3.5 2 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBZ28194.1 - 0.0007 18.8 0.0 0.019 14.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_30 PF13604.1 CBZ28194.1 - 0.0061 16.1 0.1 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF1702 PF08012.6 CBZ28194.1 - 0.0076 14.9 1.1 0.015 13.9 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1702) AAA_10 PF12846.2 CBZ28194.1 - 0.0089 15.4 0.1 0.43 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain SRP54 PF00448.17 CBZ28194.1 - 0.016 14.6 0.5 3.1 7.2 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 CBZ28194.1 - 0.026 13.6 0.0 7.4 5.6 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin RNA_helicase PF00910.17 CBZ28194.1 - 0.12 12.5 0.1 18 5.5 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 CBZ28194.1 - 0.15 12.0 0.1 0.91 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.15 CBZ28194.1 - 0.16 11.5 0.2 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase UPF0079 PF02367.12 CBZ28194.1 - 0.19 11.3 0.2 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CBZ28194.1 - 0.2 11.6 1.6 16 5.4 0.0 3.7 4 0 0 4 4 3 0 AAA domain VirE PF05272.6 CBZ28194.1 - 0.25 10.7 0.0 6.7 6.1 0.0 2.2 2 0 0 2 2 2 0 Virulence-associated protein E Herpes_LMP1 PF05297.6 CBZ28194.1 - 0.63 8.8 6.7 0.52 9.1 2.9 2.1 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) AAA_13 PF13166.1 CBZ28194.1 - 1.1 7.6 0.5 14 3.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.19 CBZ28194.1 - 1.2 8.2 53.0 0.066 12.3 12.2 4.3 4 1 0 4 4 4 0 ABC-2 type transporter ABC2_membrane_3 PF12698.2 CBZ28195.1 - 1.6e-40 139.1 16.1 2.6e-40 138.5 11.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 CBZ28195.1 - 7.4e-23 81.3 0.0 1.4e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ28195.1 - 1.4e-09 38.3 0.0 1.4e-06 28.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain DUF1702 PF08012.6 CBZ28195.1 - 0.0034 16.0 1.1 0.0057 15.3 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1702) AAA_15 PF13175.1 CBZ28195.1 - 0.0096 15.0 0.0 0.2 10.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Herpes_LMP1 PF05297.6 CBZ28195.1 - 0.071 12.0 4.1 0.13 11.2 2.8 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) AAA_23 PF13476.1 CBZ28195.1 - 0.35 11.1 1.7 0.98 9.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF872 PF05915.7 CBZ28195.1 - 0.42 10.4 2.5 1.5 8.7 1.7 1.9 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF3123 PF11321.3 CBZ28196.1 - 7.3 6.9 10.9 0.12 12.7 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3123) TatD_DNase PF01026.16 CBZ28197.1 - 2.1e-38 131.9 0.0 2.5e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 CBZ28197.1 - 3.7e-08 33.2 0.0 0.00083 18.9 0.0 2.6 1 1 0 2 2 2 2 Amidohydrolase APT PF03440.9 CBZ28197.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain DUF4325 PF14213.1 CBZ28198.1 - 0.052 13.2 0.1 0.62 9.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4325) Pyridox_ox_2 PF12900.2 CBZ28199.1 - 0.013 15.2 0.3 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase DUF896 PF05979.7 CBZ28199.1 - 0.046 13.3 0.3 0.26 10.8 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF751 PF05421.6 CBZ28201.1 - 8.9 6.6 6.3 36 4.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF751) AAA PF00004.24 CBZ28203.1 - 4.9e-87 288.8 0.0 3.4e-47 159.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBZ28203.1 - 8.9e-17 60.9 0.0 4.2e-09 35.8 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CBZ28203.1 - 1.4e-12 47.9 2.2 0.00022 21.2 0.0 4.7 3 2 2 5 5 5 2 AAA ATPase domain AAA_5 PF07728.9 CBZ28203.1 - 2.4e-11 43.5 0.1 0.00031 20.4 0.0 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CBZ28203.1 - 4.2e-11 43.0 0.0 2.1e-05 24.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBZ28203.1 - 1.2e-10 41.5 0.3 0.0022 18.1 0.0 4.6 3 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CBZ28203.1 - 1.2e-09 38.9 0.0 0.00095 19.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CBZ28203.1 - 1.4e-09 37.9 0.0 0.00067 19.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CBZ28203.1 - 4.9e-09 36.2 0.0 0.0018 18.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CBZ28203.1 - 8.6e-09 34.7 0.0 1.8e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 CBZ28203.1 - 3.5e-07 29.8 0.6 0.018 14.8 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 CBZ28203.1 - 5.1e-07 29.2 0.0 0.028 13.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 CBZ28203.1 - 7.4e-07 29.3 0.0 0.028 14.5 0.0 3.1 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.1 CBZ28203.1 - 1.1e-05 25.7 0.0 0.12 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CBZ28203.1 - 1.3e-05 24.0 0.0 0.11 11.2 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_28 PF13521.1 CBZ28203.1 - 1.6e-05 24.9 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CBZ28203.1 - 1.9e-05 24.3 0.3 0.3 10.7 0.0 3.3 3 0 0 3 3 3 2 NACHT domain AAA_3 PF07726.6 CBZ28203.1 - 2.3e-05 23.9 0.0 0.25 10.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CBZ28203.1 - 3.7e-05 22.9 0.2 0.044 12.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBZ28203.1 - 6e-05 22.5 4.8 1.8 7.9 0.0 4.1 2 2 1 4 4 4 2 AAA domain ABC_tran PF00005.22 CBZ28203.1 - 0.00017 21.8 0.6 0.32 11.2 0.0 2.9 3 1 0 3 3 2 1 ABC transporter AAA_24 PF13479.1 CBZ28203.1 - 0.00023 20.8 0.1 0.095 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CBZ28203.1 - 0.00034 19.5 0.0 0.22 10.3 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.21 CBZ28203.1 - 0.00034 20.1 0.0 0.077 12.4 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_11 PF13086.1 CBZ28203.1 - 0.00071 19.2 0.0 0.26 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CBZ28203.1 - 0.00073 19.5 0.0 0.03 14.3 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain NTPase_1 PF03266.10 CBZ28203.1 - 0.00085 19.0 0.4 0.26 10.9 0.0 3.0 3 0 0 3 3 3 1 NTPase Viral_helicase1 PF01443.13 CBZ28203.1 - 0.0018 17.8 0.0 0.43 10.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Vps4_C PF09336.5 CBZ28203.1 - 0.0019 18.0 0.1 0.0082 16.0 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain UPF0079 PF02367.12 CBZ28203.1 - 0.0029 17.2 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 CBZ28203.1 - 0.0031 17.2 0.0 1.2 8.8 0.0 2.9 2 2 0 2 2 2 1 Archaeal ATPase Bac_DnaA PF00308.13 CBZ28203.1 - 0.0031 17.1 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein Parvo_NS1 PF01057.12 CBZ28203.1 - 0.0049 15.7 0.1 0.36 9.6 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF815 PF05673.8 CBZ28203.1 - 0.014 14.3 0.0 2.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SKI PF01202.17 CBZ28203.1 - 0.028 14.2 0.0 0.42 10.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Rad17 PF03215.10 CBZ28203.1 - 0.039 12.6 0.0 0.23 10.0 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 CBZ28203.1 - 0.08 12.4 0.1 5.3 6.6 0.0 2.7 3 0 0 3 3 2 0 P-loop containing region of AAA domain KaiC PF06745.8 CBZ28203.1 - 0.098 11.7 0.3 2.5 7.1 0.0 2.8 2 1 1 3 3 3 0 KaiC cobW PF02492.14 CBZ28203.1 - 0.3 10.5 1.1 14 5.0 0.0 2.7 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Aminotran_5 PF00266.14 CBZ28204.1 - 2.1e-85 286.6 0.0 2.5e-85 286.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CBZ28204.1 - 2.5e-13 49.8 0.1 3.7e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 CBZ28204.1 - 0.00041 18.8 0.0 0.00076 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 CBZ28204.1 - 0.0019 17.3 0.1 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family AAA PF00004.24 CBZ28205.1 - 1.6e-36 125.3 0.0 4.4e-27 94.8 0.0 3.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ28205.1 - 3.3e-13 49.8 0.7 1e-06 28.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CBZ28205.1 - 5.6e-10 40.0 0.0 0.00014 22.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CBZ28205.1 - 5.7e-09 35.6 0.1 3.6e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.1 CBZ28205.1 - 1.2e-08 35.1 7.0 0.00044 20.2 0.1 4.4 3 2 1 4 4 4 2 AAA ATPase domain AAA_18 PF13238.1 CBZ28205.1 - 1.6e-08 34.9 0.0 0.0023 18.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CBZ28205.1 - 2.9e-07 30.1 2.7 0.0056 16.3 0.0 3.8 3 0 0 3 3 3 2 Part of AAA domain Mg_chelatase PF01078.16 CBZ28205.1 - 3.3e-07 29.6 0.0 0.00053 19.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBZ28205.1 - 3.8e-07 29.9 0.0 0.0061 16.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CBZ28205.1 - 7.3e-07 29.1 0.0 0.031 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 CBZ28205.1 - 1.4e-06 28.3 0.0 0.0031 17.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CBZ28205.1 - 1.7e-06 27.0 0.0 0.037 12.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_2 PF07724.9 CBZ28205.1 - 3.8e-06 26.9 0.0 0.00034 20.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_30 PF13604.1 CBZ28205.1 - 5.2e-06 26.1 0.0 0.00045 19.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CBZ28205.1 - 1.2e-05 25.4 0.0 0.013 15.5 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain DUF2075 PF09848.4 CBZ28205.1 - 2.9e-05 23.1 0.0 0.022 13.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CBZ28205.1 - 3.3e-05 24.2 0.3 0.22 11.8 0.0 2.9 2 1 1 3 3 2 2 ABC transporter Sigma54_activat PF00158.21 CBZ28205.1 - 4.1e-05 23.1 0.0 0.14 11.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.1 CBZ28205.1 - 0.00021 21.2 0.0 0.26 11.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 CBZ28205.1 - 0.00023 20.1 0.0 0.052 12.3 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.1 CBZ28205.1 - 0.00024 20.5 0.0 0.044 13.3 0.0 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 CBZ28205.1 - 0.00028 21.0 0.0 0.61 10.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase KTI12 PF08433.5 CBZ28205.1 - 0.0006 19.1 0.0 0.31 10.2 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_25 PF13481.1 CBZ28205.1 - 0.0016 17.8 1.0 0.32 10.3 0.1 3.8 4 1 0 4 4 4 1 AAA domain ArgK PF03308.11 CBZ28205.1 - 0.0039 15.9 0.5 0.021 13.6 0.2 2.2 2 0 0 2 2 2 1 ArgK protein AAA_11 PF13086.1 CBZ28205.1 - 0.004 16.7 0.0 0.19 11.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CBZ28205.1 - 0.0047 16.6 0.1 3.9 7.1 0.0 3.1 3 1 0 3 3 2 0 NACHT domain AAA_24 PF13479.1 CBZ28205.1 - 0.0049 16.4 0.4 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBZ28205.1 - 0.007 15.4 0.1 1.1 8.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zot PF05707.7 CBZ28205.1 - 0.0098 15.3 0.2 0.25 10.7 0.0 2.5 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) Viral_helicase1 PF01443.13 CBZ28205.1 - 0.011 15.2 0.0 0.07 12.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 CBZ28205.1 - 0.016 14.9 0.0 0.69 9.5 0.0 2.6 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.7 CBZ28205.1 - 0.024 13.7 0.0 7.5 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin 6PF2K PF01591.13 CBZ28205.1 - 0.031 13.3 0.0 3.7 6.5 0.0 2.3 2 0 0 2 2 2 0 6-phosphofructo-2-kinase MMR_HSR1 PF01926.18 CBZ28205.1 - 0.035 14.0 0.0 0.47 10.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 CBZ28205.1 - 0.036 14.3 0.0 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CBZ28205.1 - 0.038 13.4 1.0 0.17 11.3 0.1 2.5 2 1 1 3 3 3 0 FtsK/SpoIIIE family PRK PF00485.13 CBZ28205.1 - 0.046 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Parvo_NS1 PF01057.12 CBZ28205.1 - 0.054 12.3 0.0 2.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 CBZ28205.1 - 0.057 13.1 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 CBZ28205.1 - 0.16 11.6 0.0 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 CBZ28205.1 - 0.22 10.1 0.0 3.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein PPV_E1_C PF00519.12 CBZ28205.1 - 0.26 9.8 0.0 13 4.2 0.0 2.2 2 0 0 2 2 2 0 Papillomavirus helicase TPR_19 PF14559.1 CBZ28206.1 - 6.3e-11 42.4 19.5 0.0053 17.0 0.0 10.7 11 1 1 12 12 12 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ28206.1 - 1.4e-10 40.8 43.5 0.024 15.2 0.0 15.5 14 4 4 18 18 18 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ28206.1 - 1.9e-09 37.0 28.9 0.0014 18.2 0.0 10.3 9 4 3 12 12 12 3 TPR repeat TPR_12 PF13424.1 CBZ28206.1 - 6.4e-09 35.6 33.9 0.017 15.0 1.4 10.5 10 2 2 12 12 12 4 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ28206.1 - 2e-06 27.1 18.0 0.4 10.5 0.3 9.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ28206.1 - 4.9e-06 25.9 8.0 2 8.1 0.0 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ28206.1 - 0.00027 20.6 24.7 6.9 6.8 0.0 11.6 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ28206.1 - 0.0078 16.8 54.4 1.1 9.9 1.9 12.7 16 1 0 16 16 16 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ28206.1 - 0.012 15.7 20.2 0.15 12.3 0.0 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat EBP PF05241.7 CBZ28207.1 - 4.1e-34 117.2 3.4 5e-34 117.0 2.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein YtpI PF14007.1 CBZ28207.1 - 0.046 13.6 0.4 0.089 12.7 0.1 1.7 2 0 0 2 2 2 0 YtpI-like protein DUF2781 PF10914.3 CBZ28207.1 - 0.055 13.2 8.8 0.085 12.6 6.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) Sulfotransfer_3 PF13469.1 CBZ28208.1 - 0.13 13.1 4.0 0.095 13.6 1.1 1.9 2 0 0 2 2 2 0 Sulfotransferase family MRP PF09387.5 CBZ28209.1 - 3.1e-63 213.0 2.0 3.1e-63 213.0 1.4 2.0 1 1 1 2 2 2 1 Mitochondrial RNA binding protein MRP WGG PF10273.4 CBZ28210.1 - 0.00054 19.9 0.9 0.0023 17.9 0.6 1.9 1 1 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Glyco_transf_43 PF03360.11 CBZ28210.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 43 TPR_11 PF13414.1 CBZ28212.1 - 4.7e-34 115.8 38.2 3.3e-12 45.8 1.9 7.4 6 2 2 8 8 8 8 TPR repeat TPR_12 PF13424.1 CBZ28212.1 - 8.5e-31 105.7 33.4 3.9e-07 29.9 0.7 8.1 5 2 1 7 7 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ28212.1 - 2.5e-28 98.0 25.8 5.3e-07 30.1 0.1 7.2 7 1 1 8 8 7 6 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ28212.1 - 7.1e-24 81.7 45.6 0.0012 18.5 0.3 12.0 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ28212.1 - 7.1e-24 82.3 49.4 8.4e-05 22.0 0.7 11.7 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ28212.1 - 2.2e-19 68.4 27.3 0.00087 19.5 0.0 11.4 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ28212.1 - 1.9e-18 66.5 26.8 2.4e-05 24.5 0.8 7.9 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ28212.1 - 5.4e-16 57.0 27.6 0.033 13.9 0.0 10.3 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ28212.1 - 2.6e-15 55.5 17.5 0.0028 18.1 0.0 10.1 4 3 8 12 12 11 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ28212.1 - 4e-13 48.1 36.7 0.025 14.3 0.5 10.8 11 0 0 11 11 11 4 Tetratricopeptide repeat Apc3 PF12895.2 CBZ28212.1 - 3.4e-11 43.1 34.0 0.0006 19.8 0.6 7.3 4 2 4 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CBZ28212.1 - 5.1e-10 38.7 26.1 0.0027 17.7 0.4 10.0 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ28212.1 - 5.7e-10 38.8 27.1 0.066 13.1 0.1 10.5 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ28212.1 - 5e-05 23.0 4.2 1.3 8.8 0.0 5.7 5 2 1 6 6 6 1 Tetratricopeptide repeat Type_III_YscG PF09477.5 CBZ28212.1 - 0.00087 19.3 4.3 0.15 12.1 0.0 3.8 4 0 0 4 4 4 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_4 PF07721.9 CBZ28212.1 - 0.0079 16.5 0.7 50 4.7 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.15 CBZ28212.1 - 2 8.5 13.6 17 5.6 0.0 7.2 8 0 0 8 8 8 0 PPR repeat Fis1_TPR_C PF14853.1 CBZ28212.1 - 4.1 7.3 21.7 2.2 8.2 0.2 6.6 7 1 1 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat JmjC PF02373.17 CBZ28214.1 - 7.3e-11 42.3 2.9 1.5e-09 38.0 2.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 CBZ28214.1 - 0.0011 18.5 0.2 0.056 12.9 0.0 2.7 3 0 0 3 3 3 1 Cupin-like domain HTH_Tnp_ISL3 PF13542.1 CBZ28214.1 - 0.031 13.4 0.4 0.08 12.1 0.3 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 RAI16-like PF10257.4 CBZ28215.1 - 6.3e-08 31.9 0.0 3.9e-07 29.3 0.0 2.1 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein PP2C_2 PF13672.1 CBZ28217.1 - 3.8e-05 23.2 5.1 0.00049 19.5 1.9 2.8 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 CBZ28217.1 - 0.002 17.8 1.6 0.0079 15.9 0.5 2.4 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CBZ28217.1 - 0.088 12.1 0.1 30 3.9 0.0 3.1 3 0 0 3 3 3 0 Protein phosphatase 2C zf-rbx1 PF12678.2 CBZ28219.1 - 2.5e-08 33.9 9.0 5.7e-08 32.7 6.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CBZ28219.1 - 4.5e-08 32.8 14.5 1e-07 31.6 10.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ28219.1 - 2.2e-05 24.3 11.2 2.2e-05 24.3 7.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CBZ28219.1 - 4.4e-05 23.2 4.9 9.8e-05 22.1 3.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CBZ28219.1 - 0.0013 18.3 11.2 0.0013 18.3 7.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ28219.1 - 0.025 14.2 12.9 0.054 13.2 8.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CBZ28219.1 - 0.081 12.6 11.2 0.17 11.6 7.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4653 PF15546.1 CBZ28219.1 - 8.7 5.5 11.0 3.2 6.9 5.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) IF-2B PF01008.12 CBZ28220.1 - 1.4e-33 116.1 0.0 2.2e-33 115.4 0.0 1.5 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF501 PF04417.7 CBZ28220.1 - 0.098 12.4 0.4 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DUF3071 PF11268.3 CBZ28220.1 - 0.1 12.3 2.6 0.12 12.1 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3071) BEX PF04538.7 CBZ28221.1 - 6 7.1 10.4 25 5.1 4.4 2.9 2 1 0 2 2 2 0 Brain expressed X-linked like family RR_TM4-6 PF06459.7 CBZ28223.1 - 7.1 6.4 22.1 8.4 6.1 15.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 WD40 PF00400.27 CBZ28225.1 - 1e-22 79.0 20.7 2.7e-06 27.0 0.1 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 CBZ28226.1 - 1.3e-137 459.4 10.3 1.4e-137 459.2 7.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_efflux PF01545.16 CBZ28227.1 - 2.2e-60 204.1 11.0 2.2e-60 204.1 7.6 2.6 3 0 0 3 3 3 1 Cation efflux family UCH PF00443.24 CBZ28228.1 - 7.6e-53 179.3 1.1 1.1e-52 178.8 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ28228.1 - 6.4e-21 75.0 1.1 9.6e-21 74.4 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF2197 PF09963.4 CBZ28228.1 - 0.06 13.3 0.4 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DZR PF12773.2 CBZ28228.1 - 0.34 10.7 6.4 4.8 7.0 4.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 CBZ28228.1 - 1.2 8.9 7.3 8.3 6.2 0.8 3.2 3 0 0 3 3 3 0 zinc-ribbons PhnA_Zn_Ribbon PF08274.7 CBZ28228.1 - 1.9 8.3 5.7 3.4 7.5 0.2 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon CpXC PF14353.1 CBZ28228.1 - 4.3 7.3 6.8 2.3 8.1 0.5 2.7 3 0 0 3 3 3 0 CpXC protein zf-RING_3 PF14369.1 CBZ28228.1 - 6.8 6.7 7.6 32 4.6 0.1 3.6 3 0 0 3 3 3 0 zinc-finger Ribonucleas_3_3 PF14622.1 CBZ28230.1 - 2e-06 27.8 0.0 3.8e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CBZ28230.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease III domain LRR_6 PF13516.1 CBZ28231.1 - 4.5e-21 72.4 8.3 0.014 15.3 0.0 9.1 9 0 0 9 9 9 7 Leucine Rich repeat LRR_4 PF12799.2 CBZ28231.1 - 6.5e-12 44.8 1.2 0.0024 17.4 0.2 5.7 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ28231.1 - 1.6e-09 36.4 0.4 0.94 9.7 0.0 8.2 8 1 1 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.1 CBZ28231.1 - 8.4e-07 28.6 1.4 0.031 14.0 0.1 4.7 3 2 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 CBZ28231.1 - 7.9e-06 25.2 5.9 5.7 7.5 0.0 7.6 9 0 0 9 9 9 2 Leucine rich repeat KH_1 PF00013.24 CBZ28233.1 - 4.5e-08 32.6 0.0 9e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCCH PF00642.19 CBZ28233.1 - 0.0012 18.4 2.3 0.0033 17.0 1.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ28233.1 - 0.013 15.5 1.2 0.024 14.6 0.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Helicase_C PF00271.26 CBZ28233.1 - 0.017 15.0 0.1 0.22 11.4 0.1 2.4 1 1 0 1 1 1 0 Helicase conserved C-terminal domain SAM_2 PF07647.12 CBZ28233.1 - 0.051 13.4 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) FoP_duplication PF13865.1 CBZ28233.1 - 5.6 7.4 7.1 15 6.1 4.9 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 tRNA-synt_1d PF00750.14 CBZ28234.1 - 9.7e-92 307.5 0.1 4e-53 180.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 CBZ28234.1 - 4.7e-27 94.3 2.7 6.1e-26 90.7 0.4 2.7 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CBZ28234.1 - 2.3e-11 44.0 0.2 7.6e-11 42.4 0.1 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Ribosomal_L17 PF01196.14 CBZ28234.1 - 0.038 14.5 0.0 0.22 12.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L17 Cupin_8 PF13621.1 CBZ28235.1 - 1.5e-17 63.9 0.0 4.3e-17 62.4 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CBZ28235.1 - 2.7e-11 43.7 0.0 6e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 CBZ28235.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein F-box PF00646.28 CBZ28235.1 - 0.0046 16.5 0.6 0.021 14.4 0.4 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 CBZ28235.1 - 0.092 12.4 1.0 0.22 11.2 0.7 1.5 1 0 0 1 1 1 0 F-box-like Cupin_2 PF07883.6 CBZ28235.1 - 0.093 12.2 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Cupin domain P-mevalo_kinase PF04275.9 CBZ28236.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Phosphomevalonate kinase Mo25 PF08569.6 CBZ28236.1 - 0.04 12.9 0.2 0.078 11.9 0.1 1.3 1 1 0 1 1 1 0 Mo25-like PSP94 PF05825.6 CBZ28237.1 - 0.099 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-microseminoprotein (PSP-94) Pol_alpha_B_N PF08418.5 CBZ28238.1 - 0.095 12.2 5.6 0.14 11.6 3.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Pkinase PF00069.20 CBZ28240.1 - 4.4e-57 193.1 0.0 6.7e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28240.1 - 4e-42 144.0 0.0 6.6e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ28240.1 - 0.012 15.3 0.0 0.045 13.4 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ28240.1 - 0.03 13.2 0.0 0.074 11.9 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.6 CBZ28240.1 - 0.24 10.2 0.1 0.36 9.6 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 CBZ28240.1 - 0.28 10.4 0.0 1 8.6 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Ribosomal_L10 PF00466.15 CBZ28241.1 - 7.5e-24 83.5 0.2 1.6e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CBZ28241.1 - 6e-14 52.2 4.8 6e-14 52.2 3.3 2.5 4 0 0 4 4 4 1 60s Acidic ribosomal protein DUF1719 PF08224.6 CBZ28242.1 - 0.042 12.9 0.0 0.048 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Choline_kinase PF01633.15 CBZ28244.1 - 6.8e-21 74.8 0.1 1.4e-20 73.8 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBZ28244.1 - 7.6e-12 45.4 0.1 1.9e-11 44.1 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 CBZ28244.1 - 0.0097 15.0 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain EcKinase PF02958.15 CBZ28244.1 - 0.014 14.5 1.1 0.027 13.6 0.7 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase AAA_4 PF04326.9 CBZ28245.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Divergent AAA domain Snf7 PF03357.16 CBZ28246.1 - 3.8e-34 117.5 39.7 4.1e-34 117.4 23.8 2.0 1 1 1 2 2 2 1 Snf7 DUF2634 PF10934.3 CBZ28246.1 - 0.12 12.1 3.2 0.082 12.6 1.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2634) DUF2309 PF10070.4 CBZ28246.1 - 0.22 9.5 6.3 0.25 9.3 4.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) CENP-Q PF13094.1 CBZ28246.1 - 6 6.8 16.5 0.097 12.6 4.8 2.2 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Lge1 PF11488.3 CBZ28246.1 - 9.4 6.5 8.5 0.86 9.8 0.5 2.9 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 CBF PF03914.12 CBZ28247.1 - 1.4e-33 115.6 1.8 4.3e-33 114.0 0.1 2.6 2 0 0 2 2 2 1 CBF/Mak21 family DUF2773 PF10971.3 CBZ28247.1 - 0.0049 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2773) DUF773 PF05600.7 CBZ28247.1 - 2.8 6.6 5.6 5.4 5.6 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF773) Rpn3_C PF08375.6 CBZ28248.1 - 1.5e-22 79.7 2.6 2.2e-22 79.2 0.9 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 CBZ28248.1 - 1.7e-18 66.8 0.1 3.3e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 CBZ28248.1 - 0.06 13.2 0.8 0.18 11.7 0.6 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat cNMP_binding PF00027.24 CBZ28249.1 - 2.2e-13 49.7 0.0 6.7e-08 32.2 0.0 3.3 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain RRXRR PF14239.1 CBZ28250.1 - 0.3 10.4 3.9 0.6 9.4 2.7 1.4 1 0 0 1 1 1 0 RRXRR protein Macoilin PF09726.4 CBZ28250.1 - 0.44 8.7 7.9 0.68 8.1 5.4 1.2 1 0 0 1 1 1 0 Transmembrane protein HicB PF05534.7 CBZ28253.1 - 0.06 12.9 0.2 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 HicB family DUF543 PF04418.7 CBZ28254.1 - 1.6e-21 76.0 0.0 1.9e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) TctA PF01970.11 CBZ28254.1 - 0.0043 15.5 0.1 0.062 11.6 0.0 1.9 1 1 1 2 2 2 2 Tripartite tricarboxylate transporter TctA family GNAT_acetyltran PF12746.2 CBZ28255.1 - 7.5e-43 146.2 0.0 8.8e-43 146.0 0.0 1.0 1 0 0 1 1 1 1 GNAT acetyltransferase FR47 PF08445.5 CBZ28255.1 - 0.029 14.0 0.0 0.065 12.9 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein RNA_pol_L_2 PF13656.1 CBZ28256.1 - 6.7e-20 70.3 0.0 9.2e-20 69.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CBZ28256.1 - 5.7e-08 31.7 0.0 1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DAGAT PF03982.8 CBZ28257.1 - 3e-28 98.3 0.0 5.9e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Aa_trans PF01490.13 CBZ28259.1 - 2.4e-58 197.5 24.9 2.9e-58 197.2 17.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ28259.1 - 9.8e-11 41.0 6.6 2.1e-10 40.0 4.6 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF4231 PF14015.1 CBZ28259.1 - 4.2 7.4 10.1 0.96 9.4 0.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) HC2 PF07382.6 CBZ28261.1 - 1.1 9.0 36.6 1.3 8.8 25.4 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 IF4E PF01652.13 CBZ28262.1 - 4.4e-52 175.9 0.5 5.1e-52 175.7 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.27 CBZ28263.1 - 7.3e-15 54.2 0.0 0.0025 17.6 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat BRO1 PF03097.13 CBZ28264.1 - 4.7e-68 229.6 2.3 4.7e-68 229.6 1.6 2.1 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CBZ28264.1 - 4.3e-49 167.0 8.4 4.3e-49 167.0 5.8 2.3 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV PAT1 PF09770.4 CBZ28264.1 - 0.12 10.5 33.4 0.047 11.9 21.4 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 T2SF PF00482.18 CBZ28264.1 - 0.49 10.3 3.6 0.63 9.9 0.6 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Strumpellin PF10266.4 CBZ28266.1 - 0 1492.7 0.0 0 1492.5 0.0 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin Striatin PF08232.7 CBZ28266.1 - 0.062 13.6 0.4 0.16 12.2 0.3 1.7 1 0 0 1 1 1 0 Striatin family ThiF PF00899.16 CBZ28267.1 - 3.3e-43 146.7 0.1 5.3e-43 146.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CBZ28267.1 - 2.4e-30 103.9 0.2 5.3e-30 102.8 0.1 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 CBZ28267.1 - 9.5e-05 22.7 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 CBZ28267.1 - 0.0017 18.4 0.2 0.0057 16.7 0.1 1.8 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 CBZ28267.1 - 0.011 14.7 0.3 0.016 14.2 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 CBZ28267.1 - 0.022 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LRR_9 PF14580.1 CBZ28268.1 - 0.015 14.8 0.1 0.034 13.7 0.1 1.5 1 1 0 1 1 1 0 Leucine-rich repeat LRR_4 PF12799.2 CBZ28269.1 - 0.00054 19.5 0.0 0.002 17.7 0.0 1.9 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) zf-CCCH_2 PF14608.1 CBZ28269.1 - 0.0054 16.6 2.3 0.013 15.4 1.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type LRR_8 PF13855.1 CBZ28269.1 - 0.013 15.1 0.1 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 Leucine rich repeat LRR_9 PF14580.1 CBZ28269.1 - 0.039 13.5 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat zf-CCCH PF00642.19 CBZ28269.1 - 0.4 10.4 6.0 0.21 11.3 1.8 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) eRF1_2 PF03464.10 CBZ28271.1 - 1.3e-39 135.5 0.1 3.6e-39 134.1 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 CBZ28271.1 - 8.9e-38 129.0 1.8 1.2e-37 128.6 0.3 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.10 CBZ28271.1 - 1.9e-23 82.4 0.1 3.6e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 ATP-grasp_5 PF13549.1 CBZ28271.1 - 0.072 12.2 0.1 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain COPIIcoated_ERV PF07970.7 CBZ28273.1 - 0.061 12.9 0.4 0.092 12.3 0.3 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter DUF1154 PF06631.6 CBZ28273.1 - 2.5 7.8 9.3 0.13 11.9 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1154) BAR PF03114.13 CBZ28273.1 - 4.4 6.7 15.4 0.067 12.6 5.4 1.8 2 1 0 2 2 2 0 BAR domain CotJB PF12652.2 CBZ28273.1 - 4.4 7.4 5.3 12 6.0 1.1 3.0 2 1 1 3 3 3 0 CotJB protein DHC_N2 PF08393.8 CBZ28275.1 - 1.2e-109 366.5 2.6 1.2e-109 366.5 1.8 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 CBZ28275.1 - 2.1e-106 356.6 1.1 5.1e-106 355.3 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CBZ28275.1 - 6e-78 261.5 0.0 2.2e-77 259.6 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 CBZ28275.1 - 7.3e-37 126.4 0.8 1.7e-36 125.2 0.5 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CBZ28275.1 - 9.1e-32 109.6 0.0 3.6e-20 72.0 0.0 5.9 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 CBZ28275.1 - 2.3e-27 95.6 0.0 1.7e-26 92.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 CBZ28275.1 - 2.2e-22 79.3 8.7 4e-22 78.4 6.1 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBZ28275.1 - 1.9e-19 69.8 0.8 3.7e-18 65.5 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region D3 AAA_16 PF13191.1 CBZ28275.1 - 3.8e-13 49.8 3.2 0.0074 16.2 0.0 7.2 6 0 0 6 6 6 3 AAA ATPase domain AAA_22 PF13401.1 CBZ28275.1 - 2.9e-12 46.8 0.7 0.14 12.3 0.0 6.4 6 0 0 6 6 5 3 AAA domain AAA PF00004.24 CBZ28275.1 - 1.4e-08 35.0 0.5 0.12 12.5 0.0 6.2 6 1 0 6 6 4 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CBZ28275.1 - 6e-07 29.6 0.3 0.61 10.2 0.0 5.0 5 0 0 5 5 5 1 RNA helicase AAA_17 PF13207.1 CBZ28275.1 - 1.7e-06 28.8 0.0 0.0037 18.0 0.0 3.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CBZ28275.1 - 3.1e-06 26.4 0.2 0.00013 21.1 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CBZ28275.1 - 6.3e-05 23.2 3.3 0.0012 19.1 0.0 4.2 4 0 0 4 4 2 1 ABC transporter AAA_33 PF13671.1 CBZ28275.1 - 0.00061 19.6 0.3 0.05 13.4 0.0 4.3 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.1 CBZ28275.1 - 0.00062 19.2 0.9 0.0093 15.4 0.0 3.3 4 0 0 4 4 4 1 P-loop containing region of AAA domain ATG16 PF08614.6 CBZ28275.1 - 0.0013 18.6 3.3 0.0013 18.6 2.3 5.1 4 0 0 4 4 4 2 Autophagy protein 16 (ATG16) AAA_14 PF13173.1 CBZ28275.1 - 0.0037 17.1 0.0 6.7 6.6 0.0 4.6 4 0 0 4 4 4 0 AAA domain Miro PF08477.8 CBZ28275.1 - 0.0078 16.6 0.0 11 6.5 0.0 3.7 3 0 0 3 3 3 0 Miro-like protein AAA_21 PF13304.1 CBZ28275.1 - 0.017 15.0 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBZ28275.1 - 0.021 15.1 5.1 0.055 13.7 0.0 3.9 5 0 0 5 5 2 0 AAA domain AAA_24 PF13479.1 CBZ28275.1 - 0.057 13.0 0.3 7.2 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 CBZ28275.1 - 1.4 8.0 9.8 5.5 6.0 0.0 3.5 4 0 0 4 4 4 0 Reovirus sigma C capsid protein TMPIT PF07851.8 CBZ28275.1 - 2.1 7.3 23.9 0.021 13.9 2.0 3.6 3 0 0 3 3 3 0 TMPIT-like protein DUF4201 PF13870.1 CBZ28275.1 - 4.9 6.5 40.8 0.0034 16.8 4.1 4.8 5 0 0 5 5 3 0 Domain of unknown function (DUF4201) TBCC PF07986.7 CBZ28276.1 - 1.8e-24 85.4 2.9 6.6e-18 64.2 3.7 2.4 2 0 0 2 2 2 2 Tubulin binding cofactor C Frag1 PF10277.4 CBZ28277.1 - 3.1e-30 105.2 12.7 3.1e-30 105.2 8.8 3.9 4 1 1 5 5 5 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 CBZ28277.1 - 0.0013 18.7 0.0 0.0039 17.1 0.0 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FrhB_FdhB_C PF04432.8 CBZ28277.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Pkinase PF00069.20 CBZ28278.1 - 6.5e-31 107.4 0.0 4.3e-29 101.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28278.1 - 7.6e-12 44.8 0.3 2.2e-11 43.3 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ28278.1 - 6.9e-05 22.7 1.0 0.00016 21.4 0.7 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ28278.1 - 0.00053 19.3 1.5 0.0029 16.9 1.0 2.0 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBZ28278.1 - 0.0017 17.4 0.0 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CBZ28278.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CBZ28278.1 - 0.24 10.1 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF605 PF04652.11 CBZ28278.1 - 4.7 6.4 9.5 6.7 5.9 6.6 1.2 1 0 0 1 1 1 0 Vta1 like GTP_cyclohydroI PF01227.17 CBZ28279.1 - 0.045 13.0 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase I Pkinase PF00069.20 CBZ28280.1 - 2.7e-41 141.4 0.0 3.8e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28280.1 - 3.4e-17 62.3 0.0 5e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CBZ28280.1 - 1 8.0 0.0 1.4 7.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PEPCK_ATP PF01293.15 CBZ28281.1 - 2.8e-198 659.1 0.0 3.3e-198 658.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CBZ28281.1 - 0.05 13.4 0.1 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBZ28281.1 - 0.098 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CBZ28281.1 - 0.11 11.8 0.1 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain BRCA2 PF00634.13 CBZ28281.1 - 0.25 10.6 1.5 0.5 9.6 1.0 1.5 1 0 0 1 1 1 0 BRCA2 repeat PEPCK_ATP PF01293.15 CBZ28282.1 - 3.2e-132 441.3 0.0 3.8e-132 441.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CBZ28282.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBZ28282.1 - 0.066 12.6 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBZ28282.1 - 0.067 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.1 CBZ28282.1 - 0.16 10.3 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.15 CBZ28283.1 - 1.2e-197 657.0 0.0 1.4e-197 656.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CBZ28283.1 - 0.039 13.8 0.1 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBZ28283.1 - 0.098 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CBZ28283.1 - 0.11 11.8 0.1 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain BRCA2 PF00634.13 CBZ28283.1 - 0.25 10.6 1.5 0.5 9.6 1.0 1.5 1 0 0 1 1 1 0 BRCA2 repeat YchF-GTPase_C PF06071.8 CBZ28285.1 - 2.1e-21 75.4 0.1 4e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CBZ28285.1 - 9.5e-19 67.4 0.0 2.5e-18 66.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ28285.1 - 1.3e-07 31.0 0.0 2.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 CBZ28285.1 - 0.00056 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain ABC_tran PF00005.22 CBZ28285.1 - 0.014 15.6 0.0 0.033 14.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter ArgK PF03308.11 CBZ28285.1 - 0.04 12.6 0.0 0.077 11.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 CBZ28285.1 - 0.056 14.2 0.0 0.16 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBZ28285.1 - 0.077 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF258 PF03193.11 CBZ28285.1 - 0.084 12.0 0.0 0.37 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DSPc PF00782.15 CBZ28286.1 - 3.4e-24 84.9 0.0 5.2e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ28286.1 - 0.00072 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Gelsolin PF00626.17 CBZ28286.1 - 0.25 11.0 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Gelsolin repeat Flagellar_rod PF05149.7 CBZ28287.1 - 1.1e-109 366.0 22.7 1.1e-109 366.0 15.8 2.1 2 0 0 2 2 2 1 Paraflagellar rod protein SH3_9 PF14604.1 CBZ28287.1 - 2.6e-12 46.1 0.0 6.2e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBZ28287.1 - 4e-10 38.9 0.0 7.4e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CBZ28287.1 - 1.2e-09 37.4 0.0 2.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Mlp PF03304.8 CBZ28287.1 - 0.0058 16.6 2.1 0.52 10.3 0.8 2.7 2 0 0 2 2 2 1 Mlp lipoprotein family Rb_C PF08934.5 CBZ28287.1 - 0.0091 15.6 0.3 0.043 13.4 0.1 2.1 2 0 0 2 2 2 1 Rb C-terminal domain GSP_synth PF03738.9 CBZ28289.1 - 7.1e-26 90.3 0.2 1.4e-25 89.3 0.2 1.5 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.11 CBZ28289.1 - 1.8e-22 79.3 0.0 4.3e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 CHAP domain CP_ATPgrasp_2 PF14403.1 CBZ28289.1 - 0.1 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 YCII PF03795.9 CBZ28290.1 - 0.033 14.3 0.1 0.089 12.9 0.1 1.7 1 0 0 1 1 1 0 YCII-related domain Mre11_DNA_bind PF04152.9 CBZ28291.1 - 2.9e-31 108.6 0.0 9.2e-31 107.0 0.0 1.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CBZ28291.1 - 1.3e-17 63.8 0.5 1.8e-17 63.3 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1266 PF06889.6 CBZ28291.1 - 0.35 10.6 1.9 0.65 9.7 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) PSD5 PF07637.6 CBZ28292.1 - 0.025 14.6 0.0 0.093 12.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1595) DUF846 PF05832.7 CBZ28293.1 - 4e-20 71.9 4.1 4.9e-20 71.6 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4189 PF13827.1 CBZ28294.1 - 0.53 10.5 6.7 0.24 11.6 2.6 1.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4189) Cmc1 PF08583.5 CBZ28294.1 - 0.78 9.5 10.2 2.3 8.0 1.6 3.1 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like MIG-14_Wnt-bd PF06664.7 CBZ28296.1 - 0.028 13.2 0.3 0.028 13.2 0.2 2.0 2 1 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF898 PF05987.8 CBZ28296.1 - 0.16 10.8 5.0 0.039 12.8 0.5 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) NS3_envE PF02723.9 CBZ28296.1 - 3 7.8 7.8 0.64 9.9 0.1 2.9 3 0 0 3 3 3 0 Non-structural protein NS3/Small envelope protein E Ninjurin PF04923.7 CBZ28296.1 - 3.1 7.5 5.5 2.7 7.7 0.1 2.7 3 0 0 3 3 3 0 Ninjurin Pkinase PF00069.20 CBZ28298.1 - 1.3e-45 155.5 0.0 1.4e-41 142.4 0.0 3.4 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28298.1 - 7.8e-23 80.8 0.0 1.6e-21 76.5 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28298.1 - 2.4e-06 26.7 0.0 4.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Dpy-30 PF05186.8 CBZ28299.1 - 3.5e-06 26.3 0.1 6.3e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 Dpy-30 motif AAA_17 PF13207.1 CBZ28299.1 - 0.042 14.6 5.3 0.16 12.8 0.0 3.6 4 0 0 4 4 4 0 AAA domain PyocinActivator PF11112.3 CBZ28299.1 - 0.059 13.2 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Pyocin activator protein PrtN Epimerase PF01370.16 CBZ28299.1 - 0.12 11.7 0.0 0.73 9.2 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family IFT43 PF15305.1 CBZ28300.1 - 1.1e-06 28.7 5.7 1.1e-06 28.7 3.9 2.5 2 1 0 2 2 2 1 Intraflagellar transport protein 43 LSM PF01423.17 CBZ28301.1 - 3.7e-16 58.4 0.4 4.7e-16 58.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain FtsJ PF01728.14 CBZ28302.1 - 8.7e-58 195.2 0.1 1.4e-57 194.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.7 CBZ28302.1 - 1.9e-32 112.5 22.3 1.9e-32 112.5 15.4 3.7 3 2 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 CBZ28302.1 - 1.9e-28 99.0 4.4 1.9e-28 99.0 3.0 5.2 4 2 1 5 5 5 1 Domain of unknown function (DUF3381) TrmB PF01978.14 CBZ28302.1 - 0.012 15.2 0.2 0.037 13.7 0.2 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RabGAP-TBC PF00566.13 CBZ28303.1 - 7.3e-29 100.7 0.0 2.8e-15 56.3 0.0 3.3 3 0 0 3 3 3 3 Rab-GTPase-TBC domain GMP_PDE_delta PF05351.6 CBZ28304.1 - 2.6e-63 212.5 0.1 3e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit IncA PF04156.9 CBZ28305.1 - 7.5 6.0 7.9 11 5.5 5.5 1.1 1 0 0 1 1 1 0 IncA protein FAD-oxidase_C PF02913.14 CBZ28306.1 - 5.9e-36 124.0 0.0 8.8e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CBZ28306.1 - 6.6e-36 122.8 1.2 1.5e-35 121.7 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain Aminotran_4 PF01063.14 CBZ28307.1 - 6.4e-23 81.4 0.0 8.6e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Aminotran_4 PF01063.14 CBZ28308.1 - 6.4e-23 81.4 0.0 8.6e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Aminotran_4 PF01063.14 CBZ28309.1 - 6.4e-23 81.4 0.0 8.8e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Erv26 PF04148.8 CBZ28310.1 - 1.4e-19 70.3 13.6 9.8e-19 67.5 9.5 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Ribonuc_red_sm PF00268.16 CBZ28311.1 - 3.2e-111 370.8 0.2 3.9e-111 370.5 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain TMEM192 PF14802.1 CBZ28313.1 - 0.15 10.8 2.2 0.7 8.7 0.1 2.2 2 0 0 2 2 2 0 TMEM192 family DUF3429 PF11911.3 CBZ28315.1 - 0.015 15.3 0.4 0.025 14.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) RRM_1 PF00076.17 CBZ28316.1 - 1.1e-34 117.8 0.0 2.5e-11 43.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ28316.1 - 1.1e-31 108.6 0.0 3.6e-11 42.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ28316.1 - 2.5e-11 43.2 0.0 0.00073 19.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ28316.1 - 1.1e-08 34.7 0.1 0.04 13.6 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif zf-CCHC PF00098.18 CBZ28316.1 - 5.7e-05 22.8 0.6 0.00012 21.8 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CBZ28316.1 - 0.042 13.5 1.7 0.088 12.5 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Lipase_3 PF01764.20 CBZ28317.1 - 2.6e-13 49.8 0.0 8.1e-12 44.9 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CBZ28317.1 - 0.1 11.9 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Motile_Sperm PF00635.21 CBZ28318.1 - 2.3e-06 27.1 0.1 8.1e-06 25.4 0.1 2.0 1 1 0 1 1 1 1 MSP (Major sperm protein) domain PI3_PI4_kinase PF00454.22 CBZ28320.1 - 5.1e-14 52.2 0.0 1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF1465 PF07323.7 CBZ28320.1 - 0.002 17.7 0.2 0.0041 16.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1465) XET_C PF06955.7 CBZ28321.1 - 1.2 8.9 3.9 1.6 8.4 0.9 2.0 2 0 0 2 2 2 0 Xyloglucan endo-transglycosylase (XET) C-terminus WD40 PF00400.27 CBZ28323.1 - 7.8e-13 47.7 10.6 0.0012 18.6 0.5 7.7 8 1 0 8 8 8 3 WD domain, G-beta repeat IncA PF04156.9 CBZ28323.1 - 0.004 16.7 25.5 0.004 16.7 17.7 4.5 3 1 1 4 4 4 2 IncA protein Reo_sigmaC PF04582.7 CBZ28323.1 - 0.035 13.3 15.3 0.016 14.4 0.8 3.5 1 1 1 3 3 3 0 Reovirus sigma C capsid protein NIF PF03031.13 CBZ28324.1 - 1.8e-29 102.4 0.0 2.7e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase VKOR PF07884.9 CBZ28325.1 - 2.2e-13 50.2 19.8 1.1e-12 48.0 13.7 1.8 1 1 0 1 1 1 1 Vitamin K epoxide reductase family Thioredoxin PF00085.15 CBZ28326.1 - 3e-06 26.8 0.0 6.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 CBZ28326.1 - 7.3e-05 21.6 0.1 0.0001 21.1 0.0 1.2 1 0 0 1 1 1 1 Phosducin DUF4169 PF13770.1 CBZ28326.1 - 0.37 10.7 3.0 0.26 11.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) DSPc PF00782.15 CBZ28327.1 - 4.5e-27 94.2 0.0 6.4e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ28327.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ribosomal_L11_N PF03946.9 CBZ28328.1 - 2.3e-14 52.6 0.0 4e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBZ28328.1 - 3.2e-10 40.0 0.0 5.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Stb3 PF10330.4 CBZ28329.1 - 0.0074 15.9 0.1 11 5.8 0.0 3.3 3 0 0 3 3 3 2 Putative Sin3 binding protein DUF1451 PF07295.6 CBZ28329.1 - 0.069 12.9 0.1 0.069 12.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1451) Atg14 PF10186.4 CBZ28330.1 - 0.0067 15.4 16.8 0.035 13.0 11.6 1.9 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 EMG1 PF03587.9 CBZ28331.1 - 6.8e-40 136.5 0.0 7.9e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Tropomyosin PF00261.15 CBZ28333.1 - 0.07 12.2 0.3 0.13 11.2 0.2 1.4 1 0 0 1 1 1 0 Tropomyosin Mcp5_PH PF12814.2 CBZ28334.1 - 2.1e-16 59.9 0.1 2.8e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 CBZ28334.1 - 5.3e-05 23.3 0.3 7.5e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CBZ28334.1 - 1.6 9.0 4.2 25 5.1 2.9 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain ACOX PF01756.14 CBZ28335.1 - 1.9e-06 27.3 0.0 3.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Cupin_3 PF05899.7 CBZ28335.1 - 0.11 11.8 0.0 0.29 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Spt5-NGN PF03439.8 CBZ28336.1 - 1.5e-20 72.7 1.5 3.3e-20 71.6 0.1 2.3 3 0 0 3 3 3 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 CBZ28336.1 - 1.3e-07 31.0 3.7 0.028 14.1 0.0 4.7 4 1 0 4 4 4 2 KOW motif Spt5_N PF11942.3 CBZ28336.1 - 0.00034 21.1 14.3 0.00034 21.1 9.9 3.0 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal HAS-barrel PF09378.5 CBZ28336.1 - 0.0016 18.3 0.3 2 8.3 0.0 3.4 3 0 0 3 3 3 2 HAS barrel domain MORN PF02493.15 CBZ28337.1 - 3.9e-21 73.4 14.5 1.1e-07 31.1 0.0 5.8 5 1 0 5 5 5 3 MORN repeat DUF1408 PF07193.6 CBZ28337.1 - 0.012 15.1 0.0 0.036 13.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) HNH_3 PF13392.1 CBZ28338.1 - 0.091 12.1 0.1 0.22 10.9 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease PP2C PF00481.16 CBZ28339.1 - 1.2e-75 254.2 0.0 1.5e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ28339.1 - 0.0049 16.2 0.2 0.023 14.0 0.2 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SCRL PF06876.7 CBZ28339.1 - 0.054 13.4 0.2 0.16 11.9 0.2 1.8 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein YchF-GTPase_C PF06071.8 CBZ28340.1 - 6.7e-37 125.1 0.5 1.5e-36 123.9 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CBZ28340.1 - 6.9e-17 61.4 0.0 1.4e-16 60.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ28340.1 - 0.00024 20.3 0.0 0.0006 19.1 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_17 PF13207.1 CBZ28340.1 - 0.0024 18.6 0.1 0.023 15.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain TGS PF02824.16 CBZ28340.1 - 0.0027 17.5 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain ArgK PF03308.11 CBZ28340.1 - 0.028 13.1 0.0 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_18 PF13238.1 CBZ28340.1 - 0.057 13.7 0.0 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CBZ28340.1 - 0.08 12.7 0.2 14 5.4 0.1 2.7 2 1 1 3 3 3 0 Dynamin family Fez1 PF06818.10 CBZ28341.1 - 0.016 15.1 2.2 0.021 14.8 1.5 1.1 1 0 0 1 1 1 0 Fez1 Cpn60_TCP1 PF00118.19 CBZ28342.1 - 0.054 12.0 0.0 0.079 11.5 0.0 1.1 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Glyco_hydro_32N PF00251.15 CBZ28343.1 - 1.1e-79 267.9 3.1 1.4e-79 267.6 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CBZ28343.1 - 1.1e-05 25.7 0.0 2.1e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF3315 PF11776.3 CBZ28343.1 - 0.066 12.7 0.9 1.4 8.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3315) Synaptobrevin PF00957.16 CBZ28344.1 - 3.3e-21 74.6 0.1 4.9e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CBZ28344.1 - 6.1e-13 48.1 0.0 9.8e-13 47.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF1424 PF07232.6 CBZ28345.1 - 0.046 12.4 0.2 0.27 9.9 0.1 2.0 1 1 1 2 2 2 0 Putative rep protein (DUF1424) TPR_11 PF13414.1 CBZ28348.1 - 7.5e-21 73.5 3.8 3.2e-14 52.3 0.1 2.9 1 1 1 2 2 2 2 TPR repeat RPAP3_C PF13877.1 CBZ28348.1 - 1.8e-19 69.5 0.1 3.4e-19 68.5 0.1 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.23 CBZ28348.1 - 9.4e-13 47.1 7.9 2.6e-05 23.6 0.6 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ28348.1 - 2.9e-12 45.4 10.3 6e-05 22.6 1.3 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ28348.1 - 1e-06 28.0 0.9 0.031 14.0 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ28348.1 - 1.7e-06 27.7 1.7 1.7e-06 27.7 1.1 4.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ28348.1 - 3.3e-05 23.7 1.3 0.6 10.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ28348.1 - 0.0038 17.7 5.8 0.013 16.1 2.2 5.7 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ28348.1 - 0.0038 17.1 9.3 0.029 14.3 3.3 3.3 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ28348.1 - 0.011 15.8 3.5 0.013 15.6 0.2 2.6 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBZ28348.1 - 0.029 14.7 0.0 0.029 14.7 0.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ28348.1 - 0.057 13.8 1.2 0.057 13.8 0.8 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ28348.1 - 0.091 13.4 0.1 0.088 13.5 3.0 5.2 4 2 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ28348.1 - 3.3 7.7 13.4 14 5.7 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Dicty_REP PF05086.7 CBZ28348.1 - 5.8 4.5 4.6 8 4.0 3.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DnaJ PF00226.26 CBZ28349.1 - 5.8e-28 96.4 0.9 1e-27 95.6 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CBZ28349.1 - 1.3e-19 69.8 0.2 1.1e-15 57.3 0.0 3.7 3 1 1 4 4 4 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBZ28349.1 - 4.1e-13 49.1 15.7 6.5e-13 48.5 10.9 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CBZ28349.1 - 0.23 11.1 7.4 2.2 7.9 0.9 2.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 CBZ28349.1 - 1.7 8.5 9.1 7.8 6.3 1.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon Aldo_ket_red PF00248.16 CBZ28350.1 - 2e-43 148.2 0.0 2.6e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family TBPIP PF07106.8 CBZ28351.1 - 4.5e-09 36.0 0.0 1.6e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) UxaC PF02614.9 CBZ28351.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 Glucuronate isomerase adh_short PF00106.20 CBZ28353.1 - 1.5e-25 90.0 2.9 2.1e-25 89.5 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBZ28353.1 - 1.5e-18 67.4 0.0 1.9e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBZ28353.1 - 2.3e-14 53.4 2.5 1.1e-13 51.2 1.8 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 CBZ28353.1 - 4.2e-07 29.6 0.1 8.9e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CBZ28353.1 - 0.0023 16.8 0.0 1 8.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 CBZ28353.1 - 0.061 13.3 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 CBZ28353.1 - 0.21 10.4 0.8 0.25 10.1 0.0 1.4 2 0 0 2 2 2 0 RmlD substrate binding domain MscS_porin PF12795.2 CBZ28354.1 - 0.17 11.1 3.5 0.28 10.4 1.5 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Pkinase PF00069.20 CBZ28355.1 - 4.8e-53 179.9 0.0 5.8e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28355.1 - 9.8e-23 80.5 0.0 1.5e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28355.1 - 3.5e-05 22.9 0.0 0.17 10.8 0.0 3.0 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 CBZ28355.1 - 0.0063 16.2 1.5 0.7 9.5 0.4 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBZ28355.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CBZ28356.1 - 7.1e-68 228.5 0.0 1.8e-67 227.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28356.1 - 3e-32 111.6 0.0 4.3e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28356.1 - 0.00025 20.1 0.0 0.0023 16.9 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Prp19 PF08606.6 CBZ28357.1 - 2.1e-26 91.4 0.5 4.9e-26 90.2 0.3 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 CBZ28357.1 - 2.1e-07 30.5 12.5 0.0073 16.1 0.0 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat U-box PF04564.10 CBZ28357.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 CBZ28357.1 - 0.0012 18.2 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3312 PF11768.3 CBZ28357.1 - 0.015 13.5 0.2 0.29 9.2 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) Rtf2 PF04641.7 CBZ28357.1 - 0.13 11.4 0.2 1 8.4 0.0 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger Rib_recp_KP_reg PF05104.7 CBZ28357.1 - 7.4 7.0 9.6 16 6.0 6.7 1.5 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region TTL PF03133.10 CBZ28358.1 - 1.3e-48 165.4 0.0 1.9e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 CBZ28358.1 - 0.0013 18.5 0.0 0.033 13.9 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBZ28358.1 - 0.0095 14.7 0.0 0.75 8.4 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_YheCD PF14398.1 CBZ28358.1 - 0.015 14.0 0.0 19 3.9 0.0 3.2 2 1 1 3 3 3 0 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 CBZ28358.1 - 0.026 13.8 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CBZ28358.1 - 0.18 11.6 0.0 22 4.8 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain TFIIF_alpha PF05793.7 CBZ28358.1 - 0.33 9.2 1.4 0.58 8.4 0.9 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Kri1 PF05178.7 CBZ28359.1 - 0.034 14.4 3.4 0.057 13.6 2.3 1.3 1 0 0 1 1 1 0 KRI1-like family Myco_19_kDa PF05481.7 CBZ28359.1 - 0.057 13.2 0.6 0.073 12.8 0.5 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Dynein_heavy PF03028.10 CBZ28360.1 - 2.1e-215 716.9 0.0 3.9e-215 716.0 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ28360.1 - 1.1e-115 386.4 3.5 1.1e-115 386.4 2.4 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ28360.1 - 6.2e-96 320.3 0.2 4.2e-95 317.6 0.0 2.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ28360.1 - 4.6e-64 215.9 0.0 1e-63 214.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ28360.1 - 2.2e-54 183.7 0.9 4.2e-54 182.7 0.3 1.7 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_7 PF12775.2 CBZ28360.1 - 7.1e-53 179.4 0.0 1.3e-52 178.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 MT PF12777.2 CBZ28360.1 - 1.4e-23 83.1 11.4 1.4e-23 83.1 7.9 1.8 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ28360.1 - 5.4e-20 71.5 0.0 4.7e-05 23.1 0.0 6.2 6 1 1 7 7 7 3 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ28360.1 - 1.6e-08 34.8 2.7 0.0044 17.2 0.0 3.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ28360.1 - 5.3e-08 33.0 1.3 0.063 13.4 0.0 6.1 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.1 CBZ28360.1 - 9.7e-05 22.6 0.3 0.14 12.5 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 CBZ28360.1 - 0.00013 22.7 0.3 0.008 16.9 0.0 3.8 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 CBZ28360.1 - 0.0031 17.1 0.1 0.79 9.3 0.0 2.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CBZ28360.1 - 0.0033 17.5 3.2 3.4 7.9 0.0 4.1 4 0 0 4 4 4 1 RNA helicase AAA_16 PF13191.1 CBZ28360.1 - 0.029 14.3 0.0 0.029 14.3 0.0 6.5 6 1 0 6 6 4 0 AAA ATPase domain MobB PF03205.9 CBZ28360.1 - 0.052 13.2 0.2 0.33 10.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CBZ28360.1 - 0.2 11.9 1.4 2.4 8.4 0.0 3.1 2 0 0 2 2 2 0 ABC transporter HTH_9 PF08221.6 CBZ28361.1 - 2.5e-05 24.0 1.8 0.088 12.6 0.0 3.5 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_27 PF13463.1 CBZ28361.1 - 0.019 15.2 0.0 0.89 9.9 0.0 3.3 3 0 0 3 3 3 0 Winged helix DNA-binding domain Methyltransf_26 PF13659.1 CBZ28362.1 - 0.0033 17.4 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ28362.1 - 0.0057 17.2 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ28362.1 - 0.0088 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ28362.1 - 0.018 15.3 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Topo_C_assoc PF14370.1 CBZ28363.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal topoisomerase domain AAA PF00004.24 CBZ28364.1 - 5.6e-09 36.2 0.0 9.6e-08 32.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ28364.1 - 6.4e-08 32.8 0.0 2.8e-06 27.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ28364.1 - 0.00014 21.9 0.1 0.00098 19.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 CBZ28364.1 - 0.00017 20.6 0.0 0.00056 18.8 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_11 PF13086.1 CBZ28364.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CBZ28364.1 - 0.027 13.4 0.0 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 CBZ28364.1 - 0.04 13.6 0.0 0.65 9.6 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase KaiC PF06745.8 CBZ28364.1 - 0.066 12.3 0.9 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_19 PF13245.1 CBZ28364.1 - 0.082 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PPR PF01535.15 CBZ28365.1 - 4.2e-06 26.3 0.4 0.18 11.8 0.0 6.1 7 0 0 7 7 7 1 PPR repeat PPR_2 PF13041.1 CBZ28365.1 - 0.00025 20.9 0.2 0.26 11.2 0.0 4.7 6 0 0 6 6 6 1 PPR repeat family PPR_3 PF13812.1 CBZ28365.1 - 0.042 14.1 1.4 32 5.1 0.0 5.1 5 0 0 5 5 5 0 Pentatricopeptide repeat domain NYD-SP28 PF14772.1 CBZ28366.1 - 2.5e-06 27.5 3.6 2.5e-06 27.5 2.5 4.7 3 1 0 4 4 4 1 Sperm tail NYD-SP28_assoc PF14775.1 CBZ28366.1 - 0.00013 21.6 0.4 0.00056 19.5 0.3 2.2 1 0 0 1 1 1 1 Sperm tail C-terminal domain Ank_5 PF13857.1 CBZ28369.1 - 2.4e-05 24.4 0.3 0.011 16.0 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) IQ PF00612.22 CBZ28369.1 - 0.00015 21.1 18.0 0.91 9.3 0.0 5.0 4 0 0 4 4 4 3 IQ calmodulin-binding motif Ank_2 PF12796.2 CBZ28369.1 - 0.00023 21.4 1.7 0.00052 20.2 0.2 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ28369.1 - 0.004 16.8 1.4 0.29 11.0 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 CBZ28369.1 - 0.0045 17.1 1.4 1.9 8.9 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.1 CBZ28369.1 - 0.012 16.1 0.3 0.081 13.4 0.0 2.6 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Guanylate_cyc PF00211.15 CBZ28370.1 - 9.2e-25 87.0 0.0 2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Globin PF00042.17 CBZ28370.1 - 7.8e-09 35.8 0.2 0.0045 17.3 0.0 2.6 2 0 0 2 2 2 2 Globin Proteasome PF00227.21 CBZ28372.1 - 5.6e-40 136.6 0.0 6.4e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RNA_POL_M_15KD PF02150.11 CBZ28373.1 - 0.0003 20.4 6.5 0.0003 20.4 4.5 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 CBZ28373.1 - 0.0004 19.9 2.5 0.0004 19.9 1.7 3.2 3 2 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-Sec23_Sec24 PF04810.10 CBZ28373.1 - 0.0077 15.7 4.8 0.0077 15.7 3.4 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Ogr_Delta PF04606.7 CBZ28373.1 - 0.0084 15.7 0.7 0.0084 15.7 0.5 2.6 2 2 0 2 2 1 1 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.2 CBZ28373.1 - 0.026 14.3 1.0 0.026 14.3 0.7 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 CBZ28373.1 - 0.16 11.1 8.3 1.8 7.9 0.5 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 CBZ28373.1 - 1.6 9.0 9.6 0.36 11.1 2.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DZR PF12773.2 CBZ28373.1 - 1.7 8.5 10.9 1.5e+02 2.3 7.6 2.8 1 1 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 CBZ28373.1 - 2.4 7.8 5.6 14 5.4 3.9 2.1 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 CBZ28373.1 - 3.5 7.6 9.3 1.1 9.2 0.3 3.3 3 0 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.1 CBZ28373.1 - 3.7 7.1 12.5 0.65 9.5 0.5 3.1 2 1 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 CBZ28373.1 - 4.5 7.0 9.2 0.28 10.9 2.2 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) 7tm_1 PF00001.16 CBZ28374.1 - 0.081 12.0 3.6 0.11 11.6 2.5 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Fumble PF03630.9 CBZ28375.1 - 4.6e-75 252.5 0.0 7.5e-75 251.9 0.0 1.3 1 0 0 1 1 1 1 Fumble Exo_endo_phos PF03372.18 CBZ28375.1 - 2.1e-14 54.0 0.0 4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AMP-binding PF00501.23 CBZ28375.1 - 2.3e-14 52.6 0.4 4.8e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Exo_endo_phos_2 PF14529.1 CBZ28375.1 - 0.17 11.4 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase MFS_1 PF07690.11 CBZ28376.1 - 3.7e-34 117.9 60.4 1.4e-27 96.4 25.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ28376.1 - 0.0017 17.0 31.0 0.0028 16.2 21.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1206 PF06724.6 CBZ28376.1 - 0.085 12.6 0.0 0.085 12.6 0.0 3.4 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1206) DUF1678 PF07913.6 CBZ28377.1 - 0.013 15.0 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) RRM_1 PF00076.17 CBZ28377.1 - 0.04 13.5 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 CBZ28377.1 - 0.053 13.0 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Sporulation protein family 7 DUF2935 PF11155.3 CBZ28377.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DSPc PF00782.15 CBZ28378.1 - 1e-27 96.2 0.0 1.6e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.1 CBZ28378.1 - 2.2e-06 27.3 15.9 0.00099 18.8 2.4 3.9 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.2 CBZ28378.1 - 7.5e-05 22.2 5.1 7.5e-05 22.2 3.5 4.0 3 2 0 3 3 3 1 Leucine Rich repeats (2 copies) Y_phosphatase PF00102.22 CBZ28378.1 - 0.00046 19.5 0.0 0.00074 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_7 PF13504.1 CBZ28378.1 - 0.026 14.6 0.6 0.026 14.6 0.4 5.5 7 0 0 7 7 7 0 Leucine rich repeat CDKN3 PF05706.7 CBZ28378.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) LRR_1 PF00560.28 CBZ28378.1 - 0.12 12.5 20.8 0.6 10.3 0.2 5.7 7 0 0 7 7 7 0 Leucine Rich Repeat PTPlike_phytase PF14566.1 CBZ28378.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CBZ28378.1 - 0.18 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family LRR_6 PF13516.1 CBZ28378.1 - 4.5 7.6 7.3 19 5.7 0.2 4.3 5 0 0 5 5 5 0 Leucine Rich repeat zf-SNAP50_C PF12251.3 CBZ28380.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Histone PF00125.19 CBZ28382.1 - 1.2e-14 54.1 0.9 1.6e-14 53.7 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ28382.1 - 0.012 15.6 0.3 0.021 14.8 0.2 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cylicin_N PF15241.1 CBZ28382.1 - 0.03 14.2 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Cylicin N-terminus zf-DHHC PF01529.15 CBZ28383.1 - 4.8e-32 110.7 0.8 4.8e-32 110.7 0.6 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase DAO PF01266.19 CBZ28385.1 - 1e-38 133.1 0.0 1.7e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CBZ28385.1 - 0.00036 20.4 0.3 0.015 15.2 0.1 2.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBZ28385.1 - 0.0042 16.2 1.6 0.007 15.4 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBZ28385.1 - 0.013 15.4 1.3 0.055 13.5 0.9 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CBZ28385.1 - 0.02 13.7 1.0 0.038 12.8 0.7 1.4 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 CBZ28385.1 - 0.02 14.5 0.2 0.045 13.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 CBZ28385.1 - 0.2 10.1 2.2 0.18 10.2 0.6 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 CBZ28385.1 - 0.35 11.3 2.1 0.72 10.2 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NADH-u_ox-rdase PF10785.4 CBZ28386.1 - 5.9e-18 64.8 2.3 1.6e-17 63.5 1.6 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit PAPS_reduct PF01507.14 CBZ28388.1 - 2.1e-23 83.0 0.0 2.5e-17 63.2 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 CBZ28388.1 - 0.0053 16.2 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zf-CCCH PF00642.19 CBZ28391.1 - 7.2e-05 22.3 15.8 7.4e-05 22.3 0.9 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-HIT PF04438.11 CBZ28391.1 - 7.2e-05 22.3 11.1 7.2e-05 22.3 7.7 2.0 2 0 0 2 2 2 1 HIT zinc finger zf-CCCH_2 PF14608.1 CBZ28391.1 - 0.032 14.2 1.3 0.032 14.2 0.9 2.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Gly-rich_Ago1 PF12764.2 CBZ28391.1 - 0.75 10.4 0.1 0.75 10.4 0.0 2.7 2 0 0 2 2 2 0 Glycine-rich region of argonaut RNB PF00773.14 CBZ28394.1 - 7.1e-92 308.1 0.0 1.1e-91 307.4 0.0 1.2 1 0 0 1 1 1 1 RNB domain MtN3_slv PF03083.11 CBZ28396.1 - 1.8e-19 69.3 10.9 5.3e-11 42.2 1.8 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Tox-ODYAM1 PF15642.1 CBZ28396.1 - 0.012 14.2 0.1 0.017 13.8 0.1 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus ThiF PF00899.16 CBZ28397.1 - 5.4e-05 23.0 1.6 5.4e-05 23.0 0.2 1.6 2 0 0 2 2 2 1 ThiF family Saccharop_dh PF03435.13 CBZ28399.1 - 5.6e-29 101.2 1.0 8.2e-28 97.4 0.2 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CBZ28399.1 - 0.00025 21.1 0.1 0.00047 20.2 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBZ28399.1 - 0.00045 19.7 0.0 0.00079 18.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CBZ28399.1 - 0.01 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CBZ28399.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 CBZ28399.1 - 0.082 12.8 0.8 0.22 11.4 0.2 2.0 2 1 0 2 2 2 0 short chain dehydrogenase AAA PF00004.24 CBZ28401.1 - 7.4e-40 136.2 0.0 1.6e-39 135.0 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CBZ28401.1 - 1.4e-05 24.2 0.0 2.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Vps4_C PF09336.5 CBZ28401.1 - 3.2e-05 23.7 0.2 7.4e-05 22.5 0.2 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 CBZ28401.1 - 4.3e-05 23.6 0.1 0.00045 20.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ28401.1 - 0.00028 20.6 0.0 0.0018 18.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CBZ28401.1 - 0.00053 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CBZ28401.1 - 0.00084 18.5 0.1 0.0019 17.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CBZ28401.1 - 0.0014 19.4 0.0 0.0042 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CBZ28401.1 - 0.0016 18.1 0.1 0.095 12.3 0.0 3.1 4 0 0 4 4 4 1 NACHT domain AAA_25 PF13481.1 CBZ28401.1 - 0.0019 17.6 0.3 0.22 10.9 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 CBZ28401.1 - 0.0041 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CBZ28401.1 - 0.0043 16.2 0.1 2 7.4 0.0 2.7 2 1 1 3 3 3 1 KaiC IstB_IS21 PF01695.12 CBZ28401.1 - 0.0043 16.4 0.0 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.1 CBZ28401.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CBZ28401.1 - 0.0048 16.9 0.0 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 CBZ28401.1 - 0.0061 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBZ28401.1 - 0.0065 15.2 0.0 0.015 14.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 CBZ28401.1 - 0.0074 16.2 0.0 0.025 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_11 PF13086.1 CBZ28401.1 - 0.0081 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ28401.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 CBZ28401.1 - 0.017 15.2 0.0 0.048 13.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 CBZ28401.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 CBZ28401.1 - 0.054 12.4 0.0 0.25 10.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 CBZ28401.1 - 0.07 11.9 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 CBZ28401.1 - 0.072 13.4 0.5 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 CBZ28401.1 - 0.074 12.4 0.0 1.3 8.4 0.0 2.6 3 0 0 3 3 2 0 Guanylate kinase PhoH PF02562.11 CBZ28401.1 - 0.077 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 CBZ28401.1 - 0.12 12.0 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 CBZ28401.1 - 0.13 11.7 0.0 0.58 9.6 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain RNB PF00773.14 CBZ28406.1 - 2.7e-87 293.1 0.0 3.5e-87 292.7 0.0 1.1 1 0 0 1 1 1 1 RNB domain WD40 PF00400.27 CBZ28408.1 - 0.033 14.0 1.5 2.7 8.0 0.1 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Carb_anhydrase PF00194.16 CBZ28409.1 - 5.1e-20 71.5 0.0 1.3e-19 70.2 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Dicty_REP PF05086.7 CBZ28409.1 - 3.8 5.1 3.8 5.2 4.6 2.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AJAP1_PANP_C PF15298.1 CBZ28410.1 - 0.016 15.0 1.8 0.027 14.3 0.7 1.7 1 1 0 1 1 1 0 AJAP1/PANP C-terminus Carboxyl_trans PF01039.17 CBZ28411.1 - 1.5e-174 581.0 0.0 1.7e-174 580.8 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 CBZ28411.1 - 0.00025 20.3 0.0 0.00049 19.3 0.0 1.5 1 0 0 1 1 1 1 Malonate decarboxylase gamma subunit (MdcE) SIS PF01380.17 CBZ28411.1 - 0.096 12.2 0.0 2.7 7.5 0.0 2.7 3 0 0 3 3 3 0 SIS domain TPR_11 PF13414.1 CBZ28412.1 - 2.3e-12 46.3 0.9 4.2e-07 29.5 0.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBZ28412.1 - 6.3e-06 25.7 2.6 2 8.5 0.2 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ28412.1 - 4.2e-05 22.9 3.4 0.91 9.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ28412.1 - 8.7e-05 23.0 0.7 0.0015 19.1 0.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ28412.1 - 0.019 14.9 1.0 0.93 9.4 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ28412.1 - 0.023 15.3 0.3 49 4.9 0.1 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat zf-MYND PF01753.13 CBZ28412.1 - 0.047 13.5 13.3 0.14 12.0 9.2 1.9 1 1 0 1 1 1 0 MYND finger Pkinase PF00069.20 CBZ28414.1 - 3.3e-61 206.6 0.0 3.8e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28414.1 - 1.4e-39 135.7 0.0 1.7e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28414.1 - 4.3e-07 29.1 0.0 6.1e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ28414.1 - 0.0037 17.0 1.7 0.015 15.0 0.5 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CBZ28414.1 - 0.0044 16.3 0.0 0.0098 15.2 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CBZ28414.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CBZ28414.1 - 0.019 13.7 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 AAA_23 PF13476.1 CBZ28415.1 - 2e-21 77.2 0.0 2e-21 77.2 0.0 6.2 3 2 0 3 3 1 1 AAA domain SMC_N PF02463.14 CBZ28415.1 - 5.1e-15 55.3 0.0 3.1e-07 29.8 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CBZ28415.1 - 7.1e-13 48.2 0.5 1e-11 44.5 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 CBZ28415.1 - 2e-09 36.9 0.1 0.00031 19.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 CBZ28415.1 - 9e-09 35.6 0.0 0.0013 18.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBZ28415.1 - 0.00083 18.8 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CBZ28415.1 - 0.003 17.8 0.0 0.003 17.8 0.0 6.3 4 2 0 4 4 3 2 ABC transporter Rad50_zn_hook PF04423.9 CBZ28415.1 - 0.0074 15.7 0.1 0.0074 15.7 0.1 3.6 4 0 0 4 4 4 1 Rad50 zinc hook motif MobB PF03205.9 CBZ28415.1 - 0.013 15.1 1.0 0.55 9.9 0.1 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CBZ28415.1 - 0.014 15.1 0.4 0.26 11.0 0.0 3.5 2 0 0 2 2 2 0 Part of AAA domain DUF2256 PF10013.4 CBZ28415.1 - 0.13 12.0 0.3 0.36 10.6 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Ribosomal_S26e PF01283.14 CBZ28416.1 - 2.3e-41 140.6 4.6 2.4e-41 140.5 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Viral_NABP PF05515.6 CBZ28416.1 - 0.17 12.1 0.2 0.17 12.1 0.1 1.5 2 0 0 2 2 2 0 Viral nucleic acid binding zf-CCHC_4 PF14392.1 CBZ28416.1 - 0.44 10.2 2.8 0.77 9.4 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle Rad51 PF08423.6 CBZ28417.1 - 3.1e-136 452.2 0.5 4.9e-136 451.6 0.3 1.3 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CBZ28417.1 - 3.8e-15 55.8 0.0 6e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 CBZ28417.1 - 6.6e-09 35.8 0.0 1.6e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 CBZ28417.1 - 6.8e-09 35.2 0.2 1.1e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CBZ28417.1 - 2.5e-05 23.5 0.1 5.4e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 CBZ28417.1 - 0.0053 16.8 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain FLO_LFY PF01698.11 CBZ28417.1 - 0.017 13.9 0.1 0.37 9.5 0.0 2.3 2 0 0 2 2 2 0 Floricaula / Leafy protein DnaB_C PF03796.10 CBZ28417.1 - 0.021 13.6 0.1 0.049 12.5 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 CBZ28417.1 - 0.075 11.8 0.0 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein Mod_r PF07200.8 CBZ28418.1 - 4.6e-06 26.6 4.4 4.6e-06 26.6 3.0 1.6 2 0 0 2 2 1 1 Modifier of rudimentary (Mod(r)) protein End3 PF12761.2 CBZ28418.1 - 0.0007 19.3 4.6 0.0013 18.4 3.2 1.4 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Tropomyosin_1 PF12718.2 CBZ28418.1 - 0.0019 18.0 3.4 0.0022 17.8 1.3 1.9 2 0 0 2 2 2 1 Tropomyosin like Leu_zip PF15294.1 CBZ28418.1 - 0.0032 16.6 1.8 0.0052 15.9 1.3 1.3 1 0 0 1 1 1 1 Leucine zipper APG6 PF04111.7 CBZ28418.1 - 0.005 15.9 1.1 0.0071 15.4 0.7 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 Microtub_assoc PF07989.6 CBZ28418.1 - 0.0052 16.5 1.9 0.012 15.4 1.3 1.6 1 0 0 1 1 1 1 Microtubule associated HALZ PF02183.13 CBZ28418.1 - 0.024 14.3 1.4 0.087 12.5 0.9 2.0 1 0 0 1 1 1 0 Homeobox associated leucine zipper Herpes_UL14 PF03580.9 CBZ28418.1 - 0.024 14.4 1.1 0.039 13.7 0.7 1.4 1 0 0 1 1 1 0 Herpesvirus UL14-like protein TSC22 PF01166.13 CBZ28418.1 - 0.024 14.5 3.4 0.055 13.4 2.0 1.9 1 1 0 1 1 1 0 TSC-22/dip/bun family DivIVA PF05103.8 CBZ28418.1 - 0.026 14.5 1.0 0.026 14.5 0.7 1.7 2 0 0 2 2 1 0 DivIVA protein GAS PF13851.1 CBZ28418.1 - 0.026 13.7 6.5 0.046 12.9 4.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Adenylate_cycl PF01295.13 CBZ28418.1 - 0.029 12.6 0.0 0.035 12.3 0.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase, class-I DUF2968 PF11180.3 CBZ28418.1 - 0.04 13.2 4.9 0.1 11.9 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIC PF04977.10 CBZ28418.1 - 0.047 13.1 4.6 0.068 12.6 2.1 2.0 1 1 0 1 1 1 0 Septum formation initiator FliD_C PF07195.7 CBZ28418.1 - 0.052 12.8 0.1 0.083 12.1 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus bZIP_1 PF00170.16 CBZ28418.1 - 0.055 13.4 1.2 0.3 11.0 0.3 2.3 2 1 1 3 3 3 0 bZIP transcription factor ADIP PF11559.3 CBZ28418.1 - 0.08 12.8 6.9 0.21 11.4 4.8 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tnp_P_element PF12017.3 CBZ28418.1 - 0.11 11.7 0.4 0.16 11.1 0.3 1.4 1 0 0 1 1 1 0 Transposase protein DUF4337 PF14235.1 CBZ28418.1 - 0.11 12.3 1.9 0.15 11.8 0.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Spc24 PF08286.6 CBZ28418.1 - 0.12 12.0 2.4 0.26 10.9 1.7 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.3 CBZ28418.1 - 0.12 12.1 4.7 0.28 11.0 3.2 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 CBZ28418.1 - 0.14 11.5 2.9 0.13 11.6 0.9 1.8 2 0 0 2 2 1 0 Phage minor structural protein GP20 COG2 PF06148.6 CBZ28418.1 - 0.14 11.9 5.2 0.051 13.4 1.7 1.7 2 0 0 2 2 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF641 PF04859.7 CBZ28418.1 - 0.16 11.7 4.0 0.59 9.8 2.1 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FlaC_arch PF05377.6 CBZ28418.1 - 0.19 11.6 6.8 0.15 12.0 1.7 2.8 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) CRF PF00473.12 CBZ28418.1 - 0.2 11.7 2.3 0.82 9.8 1.6 2.0 1 0 0 1 1 1 0 Corticotropin-releasing factor family Med4 PF10018.4 CBZ28418.1 - 0.28 10.5 6.4 0.082 12.2 2.3 1.6 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 NPV_P10 PF05531.7 CBZ28418.1 - 0.33 11.2 9.4 0.51 10.6 4.1 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 CBZ28418.1 - 0.54 9.8 9.3 1.5 8.4 6.5 1.7 1 1 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 CBZ28418.1 - 3 7.9 9.7 2.4 8.2 2.9 2.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.10 CBZ28418.1 - 10 6.0 8.8 0.73 9.6 0.9 2.6 1 1 1 2 2 2 0 Basic region leucine zipper Peptidase_M8 PF01457.11 CBZ28419.1 - 1.3e-142 475.7 1.1 1.6e-142 475.4 0.7 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M10 PF00413.19 CBZ28419.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin Astacin PF01400.19 CBZ28419.1 - 0.045 13.1 0.3 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) Peptidase_M57 PF12388.3 CBZ28419.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 CBZ28419.1 - 0.078 12.5 0.1 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Pkinase PF00069.20 CBZ28420.1 - 1.3e-56 191.6 0.0 3.8e-37 127.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28420.1 - 1.1e-21 77.0 0.0 9.5e-20 70.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CBZ28420.1 - 0.0057 16.4 1.1 0.034 13.8 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ28420.1 - 0.032 13.2 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBZ28420.1 - 0.18 10.7 0.2 18 4.1 0.0 2.5 2 1 0 3 3 3 0 Kinase-like Pox_ser-thr_kin PF05445.6 CBZ28420.1 - 0.59 8.8 0.0 1.2 7.9 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase SlyX PF04102.7 CBZ28421.1 - 0.0045 17.3 6.6 2.7 8.4 2.7 3.1 2 0 0 2 2 2 2 SlyX Med9 PF07544.8 CBZ28421.1 - 0.0065 16.1 1.1 0.26 11.0 0.3 2.7 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 PP1_bind PF15276.1 CBZ28421.1 - 0.0095 15.9 1.1 1.9 8.5 0.0 3.7 3 0 0 3 3 3 1 Protein phosphatase 1 binding Retrotrans_gag PF03732.12 CBZ28421.1 - 0.22 11.5 2.9 18 5.5 0.5 2.8 3 0 0 3 3 3 0 Retrotransposon gag protein DUF3138 PF11336.3 CBZ28421.1 - 0.27 9.3 5.5 0.059 11.5 0.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3138) NPV_P10 PF05531.7 CBZ28421.1 - 0.31 11.3 2.4 7.9 6.8 0.5 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ACBP PF00887.14 CBZ28422.1 - 0.072 12.7 0.3 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Acyl CoA binding protein HYLS1_C PF15311.1 CBZ28422.1 - 0.22 11.7 2.6 1.3 9.3 0.3 1.9 1 1 1 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus Dynein_heavy PF03028.10 CBZ28423.1 - 2.4e-217 723.3 0.0 8.3e-217 721.5 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ28423.1 - 5e-122 407.3 0.3 5e-122 407.3 0.2 2.3 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ28423.1 - 1.2e-88 296.5 0.1 8.5e-88 293.7 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ28423.1 - 5.8e-59 199.2 0.1 4.6e-58 196.2 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CBZ28423.1 - 1.1e-51 174.9 0.8 2.8e-51 173.5 0.5 1.7 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CBZ28423.1 - 2.6e-46 157.9 4.2 2.6e-46 157.9 2.9 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBZ28423.1 - 4.1e-39 134.3 0.0 1e-38 133.0 0.0 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_5 PF07728.9 CBZ28423.1 - 1.8e-15 56.9 0.1 0.0004 20.1 0.0 6.4 5 2 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CBZ28423.1 - 1.5e-07 31.6 0.3 2 8.5 0.0 5.4 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 CBZ28423.1 - 1.2e-06 28.6 0.0 0.022 14.9 0.0 4.3 4 0 0 4 4 4 2 RNA helicase AAA_30 PF13604.1 CBZ28423.1 - 1.6e-06 27.8 1.3 0.63 9.5 0.0 3.8 3 0 0 3 3 3 3 AAA domain AAA PF00004.24 CBZ28423.1 - 1e-05 25.7 0.2 1 9.5 0.0 5.0 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ28423.1 - 4.4e-05 24.2 0.9 0.044 14.6 0.0 5.3 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.1 CBZ28423.1 - 0.00012 22.1 4.5 2.6 7.9 0.0 6.1 7 0 0 7 7 7 2 AAA ATPase domain AAA_19 PF13245.1 CBZ28423.1 - 0.00026 20.6 2.7 0.88 9.3 0.0 4.3 3 0 0 3 3 3 2 Part of AAA domain Baculo_PEP_C PF04513.7 CBZ28423.1 - 0.0018 18.0 4.5 2.8 7.7 0.0 5.2 5 0 0 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus T2SE PF00437.15 CBZ28423.1 - 0.002 17.1 1.9 0.34 9.7 0.0 4.2 6 0 0 6 6 6 1 Type II/IV secretion system protein AAA_18 PF13238.1 CBZ28423.1 - 0.002 18.4 0.0 0.67 10.2 0.0 4.1 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 CBZ28423.1 - 0.011 15.2 0.1 0.47 10.0 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CBZ28423.1 - 0.026 13.6 4.5 0.63 9.1 0.0 4.2 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBZ28423.1 - 0.03 13.7 2.9 9.6 5.5 0.0 4.2 4 0 0 4 4 4 0 AAA domain PhoH PF02562.11 CBZ28423.1 - 0.18 11.0 4.5 3.9 6.6 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein Pkinase PF00069.20 CBZ28424.1 - 1.8e-51 174.7 0.0 2.8e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28424.1 - 7e-36 123.6 0.0 1.1e-35 122.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28424.1 - 0.034 13.0 0.0 0.062 12.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF3113 PF11310.3 CBZ28424.1 - 0.22 11.2 0.1 0.47 10.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) ER_lumen_recept PF00810.13 CBZ28425.1 - 1.2e-51 175.0 9.4 1.2e-51 175.0 6.5 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor ATP_synt_H PF05493.8 CBZ28426.1 - 9.1e-21 73.7 6.6 9.7e-21 73.6 4.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit H PspC PF04024.7 CBZ28426.1 - 1.2 8.6 5.7 0.22 11.0 1.2 1.7 1 1 1 2 2 2 0 PspC domain DUF4131 PF13567.1 CBZ28426.1 - 3.4 7.0 5.2 3.4 7.0 3.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) WD40 PF00400.27 CBZ28427.1 - 3.6e-28 96.3 3.6 1.3e-06 28.0 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CBZ28427.1 - 0.014 15.1 0.1 5.3 6.8 0.0 3.1 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.7 CBZ28427.1 - 0.12 10.1 0.0 2.1 6.0 0.0 2.0 2 0 0 2 2 2 0 IKI3 family Copper-fist PF00649.13 CBZ28428.1 - 0.022 13.9 0.7 5.7 6.2 0.0 3.6 3 0 0 3 3 3 0 Copper fist DNA binding domain Ank_2 PF12796.2 CBZ28430.1 - 2.3e-21 75.9 3.6 7.5e-16 58.2 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ28430.1 - 3.9e-20 71.8 1.1 4e-09 36.7 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ28430.1 - 7.8e-17 60.9 2.3 3.6e-10 39.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ28430.1 - 1.6e-13 49.4 0.8 9e-05 22.3 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 CBZ28430.1 - 7.9e-13 47.5 1.6 9.5e-05 22.0 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat Metallophos PF00149.23 CBZ28431.1 - 3.7e-43 147.2 0.2 4.5e-43 146.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BTB_2 PF02214.17 CBZ28432.1 - 9.6e-12 44.9 0.0 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4539 PF15072.1 CBZ28433.1 - 4.3e-18 64.7 0.0 7.1e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) SNARE_assoc PF09335.6 CBZ28434.1 - 1.1e-09 38.5 1.0 1.1e-09 38.5 0.7 2.7 2 0 0 2 2 2 1 SNARE associated Golgi protein EF-hand_5 PF13202.1 CBZ28434.1 - 0.00064 18.9 0.0 0.0014 17.8 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CBZ28434.1 - 0.0019 17.9 0.0 0.0084 15.9 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBZ28434.1 - 0.014 14.6 0.0 0.054 12.8 0.0 2.0 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 CBZ28434.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Sas10 PF09368.5 CBZ28435.1 - 5e-20 71.4 4.6 1.5e-19 69.9 3.2 1.9 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CBZ28435.1 - 4.9e-19 68.3 1.4 1.2e-18 67.0 1.0 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family CagA PF03507.8 CBZ28437.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 CagA exotoxin Glutaredoxin2_C PF04399.8 CBZ28438.1 - 0.11 12.0 0.4 0.12 12.0 0.3 1.1 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain SNF2_N PF00176.18 CBZ28439.1 - 5.7e-58 196.0 0.0 1.1e-57 195.1 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ28439.1 - 1.1e-12 47.6 0.0 2.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 CBZ28439.1 - 2e-07 30.5 4.7 4.3e-07 29.4 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ28439.1 - 2e-07 30.9 5.3 4.6e-07 29.7 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ28439.1 - 1.2e-06 28.0 4.4 2.4e-06 27.1 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ28439.1 - 2.1e-06 27.3 5.3 4.7e-06 26.2 3.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CBZ28439.1 - 2.5e-06 27.2 5.3 6.6e-06 25.8 3.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CBZ28439.1 - 6.8e-05 22.6 4.4 0.00014 21.6 3.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CBZ28439.1 - 0.00046 19.8 1.6 0.0013 18.4 1.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.10 CBZ28439.1 - 0.00064 19.6 0.1 0.0034 17.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-4CXXC_R1 PF10497.4 CBZ28439.1 - 0.0041 17.2 5.7 0.01 15.9 3.9 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Sec20 PF03908.8 CBZ28439.1 - 0.097 12.3 1.0 0.81 9.4 0.2 2.5 2 0 0 2 2 2 0 Sec20 RPE65 PF03055.10 CBZ28440.1 - 0.11 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein PAP_assoc PF03828.14 CBZ28442.1 - 1.9e-12 46.9 0.0 3.9e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase DSPc PF00782.15 CBZ28443.1 - 2.2e-17 62.9 0.0 1.8e-16 59.9 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain EF-hand_7 PF13499.1 CBZ28444.1 - 1e-12 47.9 0.0 5.3e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ28444.1 - 3.7e-12 44.6 1.5 3.1e-05 22.9 0.0 4.1 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.1 CBZ28444.1 - 1.6e-10 40.7 0.0 1.4e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_6 PF13405.1 CBZ28444.1 - 7.3e-10 37.8 1.8 3.7e-05 23.2 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 CBZ28444.1 - 1.7e-08 33.9 0.2 4.5e-05 22.9 0.0 3.8 1 1 3 4 4 4 3 EF-hand domain pair DDT PF02791.12 CBZ28444.1 - 0.011 15.5 0.2 0.74 9.6 0.0 2.3 2 0 0 2 2 2 0 DDT domain EF-hand_5 PF13202.1 CBZ28444.1 - 0.19 11.1 2.4 10 5.6 0.0 3.4 3 0 0 3 3 3 0 EF hand RNA_pol_Rpb8 PF03870.10 CBZ28445.1 - 5.4e-27 94.6 0.0 6.1e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 CSD PF00313.17 CBZ28448.1 - 7.1e-16 57.7 0.2 9.3e-16 57.3 0.2 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain RCC1_2 PF13540.1 CBZ28448.1 - 0.058 13.0 0.1 0.92 9.2 0.1 2.4 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat Chorion_3 PF05387.6 CBZ28450.1 - 0.095 12.1 1.2 0.11 11.9 0.8 1.1 1 0 0 1 1 1 0 Chorion family 3 DUF1738 PF08401.6 CBZ28451.1 - 0.036 13.7 0.0 0.9 9.2 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1738) MCM PF00493.18 CBZ28452.1 - 4.2e-129 430.1 0.0 6.3e-129 429.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBZ28452.1 - 7.9e-14 52.1 2.3 4.9e-13 49.6 0.2 2.5 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.3 CBZ28452.1 - 5.6e-13 49.1 30.2 5.6e-13 49.1 21.0 3.1 3 1 0 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.16 CBZ28452.1 - 1e-07 31.3 0.0 1e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBZ28452.1 - 1.9e-05 24.4 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBZ28452.1 - 0.0021 17.6 0.0 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CBZ28452.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBZ28452.1 - 0.08 12.4 0.0 0.34 10.3 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain CAP_N PF01213.14 CBZ28452.1 - 0.14 11.4 0.1 0.29 10.3 0.1 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2267 PF10025.4 CBZ28453.1 - 0.022 14.8 0.2 0.057 13.4 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Cytochrom_B558a PF05038.8 CBZ28453.1 - 0.17 11.4 1.9 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit IATP PF04568.7 CBZ28453.1 - 0.55 10.3 3.5 0.75 9.8 0.9 2.1 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP LMBR1 PF04791.11 CBZ28454.1 - 0.012 14.2 0.0 0.015 13.9 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Baculo_11_kDa PF06143.6 CBZ28454.1 - 0.08 12.3 0.0 0.21 10.9 0.0 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family Shisa PF13908.1 CBZ28454.1 - 0.22 11.7 0.9 0.45 10.6 0.6 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Ribonuc_red_lgC PF02867.10 CBZ28456.1 - 1.6e-213 710.1 0.0 1.9e-213 709.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CBZ28456.1 - 9.5e-24 83.0 0.0 2.6e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CBZ28456.1 - 2.8e-12 46.8 0.0 8.4e-12 45.3 0.0 1.9 2 0 0 2 2 2 1 ATP cone domain Filament PF00038.16 CBZ28457.1 - 0.047 13.1 24.0 0.3 10.5 5.7 2.3 1 1 1 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.5 CBZ28457.1 - 0.08 13.0 11.5 0.093 12.8 6.4 2.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Lebercilin PF15619.1 CBZ28457.1 - 0.14 11.5 29.6 2.6 7.4 18.1 3.1 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease T5orf172 PF10544.4 CBZ28457.1 - 0.15 12.5 1.4 0.29 11.5 0.5 1.9 1 1 0 1 1 1 0 T5orf172 domain HrpA_pilin PF09589.5 CBZ28457.1 - 0.3 11.5 3.2 6.5 7.2 2.2 2.6 1 1 0 1 1 1 0 HrpA pilus formation protein TMF_DNA_bd PF12329.3 CBZ28457.1 - 4 7.3 22.5 30 4.5 4.6 4.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 CBZ28457.1 - 4.2 6.3 23.5 0.75 8.7 9.7 2.5 1 1 2 3 3 3 0 Autophagy protein Apg6 TBPIP PF07106.8 CBZ28457.1 - 4.9 6.6 17.9 3.4 7.1 6.4 2.9 2 1 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 CBZ28457.1 - 5.2 6.9 7.7 7.4 6.3 1.2 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 CBZ28457.1 - 7.7 6.4 9.0 16 5.4 0.1 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Peptidase_S15 PF02129.13 CBZ28457.1 - 7.8 5.8 7.7 85 2.4 5.3 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Exo_endo_phos PF03372.18 CBZ28458.1 - 0.00018 21.5 0.0 0.48 10.3 0.0 3.6 3 0 0 3 3 3 2 Endonuclease/Exonuclease/phosphatase family DUF1786 PF08735.5 CBZ28458.1 - 0.19 10.8 0.1 0.32 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative pyruvate format-lyase activating enzyme (DUF1786) Raptor_N PF14538.1 CBZ28459.1 - 0.016 15.0 0.2 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF4381 PF14316.1 CBZ28460.1 - 0.036 14.1 0.5 0.036 14.1 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) MAS20 PF02064.10 CBZ28460.1 - 4.2 7.3 9.0 0.7 9.8 2.6 2.3 3 0 0 3 3 3 0 MAS20 protein import receptor adh_short PF00106.20 CBZ28461.1 - 2.7e-06 27.3 0.0 0.00063 19.6 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CBZ28461.1 - 0.00019 21.2 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Tctex-1 PF03645.8 CBZ28462.1 - 1.4e-25 89.1 0.2 1.6e-25 88.8 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family Ribosomal_S11 PF00411.14 CBZ28463.1 - 7.6e-41 138.7 0.7 9.3e-41 138.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 CBZ28463.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) SM-ATX PF14438.1 CBZ28464.1 - 0.00061 19.6 0.1 0.0012 18.7 0.1 1.5 1 1 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 CBZ28464.1 - 0.0028 17.1 0.0 0.004 16.6 0.0 1.5 1 1 0 1 1 1 1 LSM domain DUF2642 PF10842.3 CBZ28464.1 - 0.098 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) MtN3_slv PF03083.11 CBZ28465.1 - 0.066 13.0 0.4 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Serinc PF03348.10 CBZ28466.1 - 7.3e-52 176.5 34.1 3.1e-39 134.9 15.8 2.0 1 1 1 2 2 2 2 Serine incorporator (Serinc) Ribosomal_S10 PF00338.17 CBZ28468.1 - 3.4e-25 87.7 0.3 3.9e-25 87.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Endomucin PF07010.7 CBZ28468.1 - 0.035 13.4 2.7 0.033 13.5 1.4 1.2 1 1 0 1 1 1 0 Endomucin Ribosomal_S10 PF00338.17 CBZ28469.1 - 3.4e-25 87.7 0.3 3.9e-25 87.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Endomucin PF07010.7 CBZ28469.1 - 0.035 13.4 2.7 0.033 13.5 1.4 1.2 1 1 0 1 1 1 0 Endomucin PPR_2 PF13041.1 CBZ28470.1 - 3.3e-07 30.1 0.1 0.37 10.7 0.0 5.4 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.1 CBZ28470.1 - 1.6e-06 27.9 6.9 0.13 12.6 0.0 6.0 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 CBZ28470.1 - 1.3e-05 24.8 0.9 0.11 12.5 0.0 4.8 5 0 0 5 5 5 2 PPR repeat Ribosomal_S10 PF00338.17 CBZ28471.1 - 3.4e-25 87.7 0.3 3.9e-25 87.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Endomucin PF07010.7 CBZ28471.1 - 0.035 13.4 2.7 0.033 13.5 1.4 1.2 1 1 0 1 1 1 0 Endomucin CENP-F_leu_zip PF10473.4 CBZ28472.1 - 0.95 9.3 8.8 5.8 6.7 1.1 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.1 CBZ28472.1 - 0.97 9.4 8.8 0.057 13.3 1.1 2.6 2 0 0 2 2 2 0 FlxA-like protein HMG_box_2 PF09011.5 CBZ28476.1 - 0.0056 17.0 0.9 3.3 8.1 0.0 2.8 2 0 0 2 2 2 2 HMG-box domain DUF1104 PF06518.6 CBZ28476.1 - 0.018 15.1 5.9 1.9 8.6 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) HGTP_anticodon2 PF12745.2 CBZ28476.1 - 0.047 12.8 0.6 0.089 11.9 0.4 1.4 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs ATP-grasp_4 PF13535.1 CBZ28477.1 - 2.2e-23 82.9 0.1 9.2e-16 58.0 0.1 3.4 2 1 1 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBZ28477.1 - 1.8e-06 26.9 0.0 0.00039 19.2 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 CBZ28477.1 - 3.1e-06 27.1 0.0 0.00012 21.9 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CBZ28477.1 - 7.3e-05 22.1 0.0 0.0051 16.1 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 CBZ28477.1 - 0.00067 19.2 0.1 0.0015 18.1 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.1 CBZ28477.1 - 0.045 12.8 0.0 0.56 9.2 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp TMEM190 PF15431.1 CBZ28478.1 - 0.12 12.3 0.2 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 190 zf-UBR PF02207.15 CBZ28479.1 - 4.1e-08 32.8 25.9 1.6e-07 30.9 7.2 5.1 5 1 1 6 6 6 3 Putative zinc finger in N-recognin (UBR box) ubiquitin PF00240.18 CBZ28479.1 - 1e-05 24.8 0.1 2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family M-inducer_phosp PF06617.8 CBZ28479.1 - 0.036 13.1 0.1 0.08 11.9 0.1 1.5 1 0 0 1 1 1 0 M-phase inducer phosphatase WD40 PF00400.27 CBZ28480.1 - 5.9e-47 155.9 30.2 5.8e-06 25.9 0.0 10.5 10 0 0 10 10 10 10 WD domain, G-beta repeat eIF2A PF08662.6 CBZ28480.1 - 1.6e-06 27.9 0.0 0.057 13.1 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 CBZ28480.1 - 1.7e-05 24.4 2.4 0.0044 16.5 0.4 3.3 2 1 2 4 4 4 2 PQQ-like domain Gmad1 PF10647.4 CBZ28480.1 - 0.0004 19.8 1.3 0.18 11.1 0.1 2.8 3 0 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain PQQ_3 PF13570.1 CBZ28480.1 - 0.0078 16.4 9.5 55 4.2 0.0 7.1 6 1 1 7 7 7 0 PQQ-like domain Amastin PF07344.6 CBZ28481.1 - 0.0012 18.4 11.6 0.002 17.7 8.0 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 CBZ28481.1 - 0.17 11.5 11.6 0.42 10.2 8.1 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Amastin PF07344.6 CBZ28482.1 - 2.1e-32 111.8 24.0 8.5e-21 74.1 4.0 2.3 2 0 0 2 2 2 2 Amastin surface glycoprotein ETF_alpha PF00766.14 CBZ28483.1 - 3.2e-37 126.0 1.0 1.5e-36 123.8 0.1 2.3 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 CBZ28483.1 - 5.2e-26 91.3 1.1 8.9e-26 90.5 0.8 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AMP-binding PF00501.23 CBZ28484.1 - 3.9e-51 173.7 2.3 2.5e-48 164.5 0.5 3.0 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 CBZ28484.1 - 5.8e-09 36.7 0.5 1.6e-08 35.3 0.3 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP-synt_C PF00137.16 CBZ28485.1 - 4.6e-29 100.1 42.1 1.6e-18 66.3 6.8 3.1 3 0 0 3 3 3 3 ATP synthase subunit C GerA PF03323.8 CBZ28485.1 - 0.29 9.2 2.8 3.5 5.6 0.2 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF2592 PF10766.4 CBZ28485.1 - 7.3 6.0 13.8 0.11 11.8 3.9 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2592) LRR_4 PF12799.2 CBZ28486.1 - 0.0017 17.9 1.0 0.23 11.1 0.0 2.9 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBZ28486.1 - 0.0025 17.7 1.2 0.16 12.0 0.3 2.9 2 0 0 2 2 2 1 Leucine Rich repeat LRR_1 PF00560.28 CBZ28486.1 - 0.023 14.6 1.9 5 7.5 0.2 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 CBZ28486.1 - 0.17 12.1 5.3 6.9 7.3 0.1 4.3 4 0 0 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 CBZ28486.1 - 1.4 8.7 5.8 3.2 7.5 0.0 3.1 4 0 0 4 4 4 0 Leucine rich repeat zf-AN1 PF01428.11 CBZ28487.1 - 3e-08 33.3 9.7 4.6e-08 32.7 6.7 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CBZ28487.1 - 0.0041 17.3 3.7 0.0074 16.4 2.6 1.5 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain DUF4407 PF14362.1 CBZ28487.1 - 0.43 9.4 3.7 0.43 9.4 2.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Copine PF07002.11 CBZ28489.1 - 1.7e-44 151.1 0.0 2.8e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Copine C2 PF00168.25 CBZ28489.1 - 1.1e-26 92.4 0.0 4e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 CBZ28489.1 - 5.2e-07 29.6 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 CBZ28489.1 - 9.8e-05 22.5 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CBZ28489.1 - 0.034 13.8 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain HSP70 PF00012.15 CBZ28490.1 - 6.2e-256 850.0 12.3 7e-256 849.8 8.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ28490.1 - 1.2e-21 76.6 0.4 4.9e-19 68.0 0.0 2.3 1 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CBZ28490.1 - 0.0015 18.1 0.0 0.0034 17.0 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 CBZ28490.1 - 0.0019 17.3 0.1 0.0019 17.3 0.1 3.1 4 0 0 4 4 4 1 Hydantoinase/oxoprolinase DUF3419 PF11899.3 CBZ28490.1 - 0.085 11.5 0.1 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) WWE PF02825.15 CBZ28492.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 WWE domain CDC45 PF02724.9 CBZ28492.1 - 3.9 5.3 11.7 1.9 6.4 5.7 1.9 2 0 0 2 2 2 0 CDC45-like protein SGL PF08450.7 CBZ28493.1 - 1.9e-38 132.2 0.0 1.1e-37 129.7 0.0 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region FAD_binding_1 PF00667.15 CBZ28494.1 - 3e-43 147.8 0.0 4.9e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CBZ28494.1 - 1.5e-34 119.0 1.7 4.4e-34 117.5 0.1 2.3 2 1 1 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.16 CBZ28494.1 - 1.1e-14 54.9 0.0 4e-14 53.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 CBZ28494.1 - 0.042 13.7 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like EMP24_GP25L PF01105.19 CBZ28495.1 - 0.42 10.3 3.1 0.71 9.5 2.1 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF3373 PF11853.3 CBZ28495.1 - 2.8 6.3 4.3 4 5.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) APG6 PF04111.7 CBZ28495.1 - 2.8 6.8 10.5 4.1 6.3 7.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CBZ28495.1 - 7 6.1 12.2 11 5.5 8.5 1.3 1 0 0 1 1 1 0 IncA protein DnaJ PF00226.26 CBZ28497.1 - 6.3e-17 61.0 0.5 1.1e-16 60.2 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Biopterin_H PF00351.16 CBZ28498.1 - 4e-123 410.3 0.0 5.4e-123 409.9 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase zf-C3HC4_3 PF13920.1 CBZ28500.1 - 8.6e-06 25.3 7.1 1.5e-05 24.5 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ28500.1 - 1.7e-05 24.7 12.9 2.8e-05 24.0 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ28500.1 - 2.5e-05 23.9 7.4 4.1e-05 23.2 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CBZ28500.1 - 4.6e-05 22.9 9.3 7.8e-05 22.2 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ28500.1 - 8.9e-05 22.2 14.2 0.00014 21.6 9.8 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CBZ28500.1 - 0.00061 19.5 11.3 0.0011 18.7 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 CBZ28500.1 - 0.0068 16.0 6.8 0.014 15.0 4.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CBZ28500.1 - 0.035 13.8 5.3 0.12 12.1 3.8 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Matrilin_ccoil PF10393.4 CBZ28500.1 - 0.21 10.9 4.6 0.82 9.0 0.4 2.8 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin zf-MIZ PF02891.15 CBZ28500.1 - 0.72 9.4 8.9 1.3 8.6 6.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-HIT PF04438.11 CBZ28500.1 - 1.4 8.6 5.5 0.6 9.8 0.8 2.1 2 0 0 2 2 2 0 HIT zinc finger Rad50_zn_hook PF04423.9 CBZ28500.1 - 1.4 8.4 0.0 1.4 8.4 0.0 3.6 4 0 0 4 4 4 0 Rad50 zinc hook motif DUF1610 PF07754.6 CBZ28500.1 - 1.7 8.8 8.9 7 6.8 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) CorA PF01544.13 CBZ28500.1 - 2.7 6.9 7.4 1.8 7.5 3.7 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF342 PF03961.8 CBZ28500.1 - 3.6 5.8 7.1 3.4 5.9 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) zf-rbx1 PF12678.2 CBZ28500.1 - 3.7 7.7 6.4 13 5.9 4.5 1.7 1 1 1 2 2 2 0 RING-H2 zinc finger DivIVA PF05103.8 CBZ28500.1 - 5.8 6.9 11.1 0.35 10.9 2.6 2.4 3 0 0 3 3 3 0 DivIVA protein Mnd1 PF03962.10 CBZ28500.1 - 6.5 6.3 13.1 55 3.3 0.0 2.9 2 1 0 2 2 2 0 Mnd1 family DEAD PF00270.24 CBZ28501.1 - 2.5e-39 134.5 0.0 8e-39 132.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ28501.1 - 1.8e-21 75.8 0.0 4.8e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBZ28501.1 - 1.8e-14 53.0 0.1 4e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBZ28501.1 - 0.0035 17.1 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2753 PF10952.3 CBZ28501.1 - 0.0058 16.6 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2753) DUF3393 PF11873.3 CBZ28501.1 - 0.032 13.7 0.2 0.064 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) UbiA PF01040.13 CBZ28502.1 - 3.1e-26 92.1 19.5 4.7e-26 91.5 13.5 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family TP2 PF01254.13 CBZ28503.1 - 8.9 6.6 11.2 9.9 6.5 6.6 1.9 1 1 1 2 2 2 0 Nuclear transition protein 2 Hydrolase_3 PF08282.7 CBZ28504.1 - 1.2e-19 70.9 0.0 1.8e-18 67.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CBZ28504.1 - 1.1e-05 24.8 0.0 1.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Calici_MSP PF05752.6 CBZ28504.1 - 0.084 12.4 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Calicivirus minor structural protein Hydrolase_3 PF08282.7 CBZ28505.1 - 4.2e-36 124.8 0.0 1.2e-34 120.0 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CBZ28505.1 - 7.1e-10 38.5 0.0 0.00014 21.2 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.11 CBZ28505.1 - 0.0059 15.5 0.1 2.9 6.7 0.0 2.3 2 0 0 2 2 2 2 Trehalose-phosphatase Hydrolase PF00702.21 CBZ28505.1 - 0.021 15.2 3.7 0.34 11.2 2.6 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ28505.1 - 0.036 14.2 3.6 1.8 8.6 2.5 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBZ28506.1 - 3e-52 177.7 0.0 3.9e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CBZ28506.1 - 1.2e-15 57.5 0.0 7.5e-07 28.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CBZ28506.1 - 1.4e-11 45.2 0.1 1.1e-10 42.3 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ28506.1 - 1.8e-06 28.2 0.5 0.00018 21.7 0.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CBZ28506.1 - 0.0028 17.5 0.0 0.0089 15.8 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBZ28507.1 - 4.5e-51 173.8 0.0 5.3e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CBZ28507.1 - 6.5e-19 68.1 0.0 9.2e-09 34.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CBZ28507.1 - 4.7e-06 27.1 0.2 0.00038 20.9 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CBZ28507.1 - 0.028 14.3 0.0 0.075 12.9 0.0 1.8 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.11 CBZ28507.1 - 0.067 12.0 0.0 0.24 10.2 0.0 1.9 2 0 0 2 2 2 0 Trehalose-phosphatase Glyoxalase_2 PF12681.2 CBZ28507.1 - 0.12 13.0 0.0 0.27 11.8 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase-like domain HAD PF12710.2 CBZ28507.1 - 0.27 11.3 2.0 3.8 7.6 0.1 2.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBZ28508.1 - 7.9e-49 166.5 0.0 8e-32 110.8 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CBZ28508.1 - 9.9e-15 54.5 0.0 2.2e-09 37.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 CBZ28508.1 - 1.4e-06 28.8 0.0 0.072 13.4 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ28508.1 - 0.00031 20.9 0.2 0.032 14.3 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBZ28508.1 - 0.08 13.1 0.0 0.96 9.6 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Amastin PF07344.6 CBZ28509.1 - 1.2e-45 154.9 4.6 1.5e-45 154.5 3.2 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.6 CBZ28510.1 - 1.3e-31 109.3 8.1 2.3e-31 108.5 5.6 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein zf-CCCH PF00642.19 CBZ28511.1 - 0.00011 21.7 3.8 0.00022 20.8 2.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IMS PF00817.15 CBZ28512.1 - 8.2e-35 119.7 0.0 2.1e-34 118.4 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CBZ28512.1 - 2e-13 50.3 0.1 5.8e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CBZ28512.1 - 9.2e-05 22.2 0.0 0.00024 20.9 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif HHH_5 PF14520.1 CBZ28512.1 - 0.048 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain IMS PF00817.15 CBZ28513.1 - 2.1e-38 131.4 0.0 3.9e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CBZ28513.1 - 5.8e-18 65.0 0.2 1.4e-17 63.7 0.2 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CBZ28513.1 - 0.00034 20.4 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif zf-Tim10_DDP PF02953.10 CBZ28513.1 - 0.11 11.7 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Tim10/DDP family zinc finger IMS PF00817.15 CBZ28514.1 - 2.3e-36 124.8 0.0 4.3e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CBZ28514.1 - 5.6e-07 29.5 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CBZ28514.1 - 2.5e-06 27.1 0.0 6.1e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif SUI1 PF01253.17 CBZ28514.1 - 0.18 11.6 0.0 0.42 10.4 0.0 1.6 1 1 0 1 1 1 0 Translation initiation factor SUI1 IMS PF00817.15 CBZ28515.1 - 0.33 10.7 2.6 2.5 7.8 0.6 2.9 2 1 0 2 2 2 0 impB/mucB/samB family AAA PF00004.24 CBZ28517.1 - 8.1e-32 110.1 0.0 1.9e-21 76.6 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CBZ28517.1 - 1.2e-08 34.5 0.0 4.9e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_16 PF13191.1 CBZ28517.1 - 1.5e-08 34.8 5.8 0.00058 19.8 0.3 4.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 CBZ28517.1 - 1.6e-08 34.5 0.0 0.00044 20.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CBZ28517.1 - 1.8e-08 34.5 0.0 7.9e-05 22.8 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBZ28517.1 - 3.5e-08 33.2 0.0 7.6e-06 25.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ28517.1 - 1.5e-07 32.2 0.0 1.4e-05 25.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBZ28517.1 - 2.2e-06 27.5 0.0 2.1e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CBZ28517.1 - 3.4e-06 26.2 0.0 6.1e-05 22.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CBZ28517.1 - 5.3e-06 25.7 0.2 0.0033 16.6 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CBZ28517.1 - 9.2e-06 25.7 0.0 0.013 15.6 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 CBZ28517.1 - 1.7e-05 24.4 0.0 0.0037 16.9 0.0 3.2 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 CBZ28517.1 - 1.9e-05 23.8 0.0 0.054 12.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 CBZ28517.1 - 2.7e-05 23.6 0.2 0.021 14.2 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_2 PF07724.9 CBZ28517.1 - 0.00017 21.5 0.0 0.026 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.7 CBZ28517.1 - 0.00019 21.1 0.0 0.0074 15.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF815 PF05673.8 CBZ28517.1 - 0.00035 19.5 0.0 0.035 13.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CBZ28517.1 - 0.00038 20.4 0.0 0.075 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CBZ28517.1 - 0.0011 17.8 0.0 0.0026 16.5 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_29 PF13555.1 CBZ28517.1 - 0.0016 17.9 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 CBZ28517.1 - 0.0018 17.2 0.0 0.42 9.4 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein TniB PF05621.6 CBZ28517.1 - 0.0028 16.4 0.1 0.077 11.7 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein ABC_tran PF00005.22 CBZ28517.1 - 0.0049 17.1 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter MCM PF00493.18 CBZ28517.1 - 0.0067 15.2 0.0 0.17 10.6 0.0 2.3 2 0 0 2 2 2 1 MCM2/3/5 family PhoH PF02562.11 CBZ28517.1 - 0.0069 15.6 0.0 0.043 13.0 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein Sigma54_activat PF00158.21 CBZ28517.1 - 0.0098 15.3 0.0 0.14 11.5 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain UPF0079 PF02367.12 CBZ28517.1 - 0.012 15.2 0.0 0.15 11.6 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 CBZ28517.1 - 0.013 15.1 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CBZ28517.1 - 0.013 15.1 0.0 3.4 7.2 0.0 3.0 2 1 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 CBZ28517.1 - 0.025 14.1 0.0 0.86 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 CBZ28517.1 - 0.026 14.1 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 CBZ28517.1 - 0.026 14.1 0.0 0.37 10.3 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 CBZ28517.1 - 0.037 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 CBZ28517.1 - 0.047 13.5 0.0 0.095 12.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase KTI12 PF08433.5 CBZ28517.1 - 0.051 12.7 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 CBZ28517.1 - 0.059 13.0 0.0 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 NTPase Parvo_NS1 PF01057.12 CBZ28517.1 - 0.062 12.1 0.0 0.41 9.4 0.0 1.9 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CBZ28517.1 - 0.069 13.2 0.0 0.4 10.7 0.0 2.3 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_10 PF12846.2 CBZ28517.1 - 0.086 12.2 0.0 12 5.1 0.0 2.9 2 2 1 3 3 3 0 AAA-like domain Guanylate_kin PF00625.16 CBZ28517.1 - 0.097 12.1 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase AAA_24 PF13479.1 CBZ28517.1 - 0.25 10.8 0.1 0.67 9.5 0.1 1.7 1 0 0 1 1 1 0 AAA domain SNARE PF05739.14 CBZ28518.1 - 1.8e-16 59.5 1.2 5.9e-16 57.9 0.8 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 CBZ28518.1 - 7.3e-07 29.3 1.0 7.3e-07 29.3 0.7 2.6 2 1 0 2 2 2 1 Syntaxin Hrs_helical PF12210.3 CBZ28518.1 - 0.62 10.3 6.1 1.5 9.1 0.0 3.1 2 1 1 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF3708 PF12501.3 CBZ28518.1 - 1.1 9.0 7.0 2.1 8.1 1.0 2.4 2 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter APG6 PF04111.7 CBZ28518.1 - 1.5 7.8 16.9 0.11 11.5 5.2 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF423 PF04241.10 CBZ28519.1 - 9.9e-17 60.6 1.0 1.5e-16 60.0 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) NOG1 PF06858.9 CBZ28519.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) DUF423 PF04241.10 CBZ28520.1 - 5.1e-19 67.9 0.7 6.7e-19 67.6 0.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF423) NADH-u_ox-rdase PF10785.4 CBZ28520.1 - 0.0065 16.6 0.6 0.011 15.9 0.3 1.5 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit GerA PF03323.8 CBZ28520.1 - 0.029 12.5 0.1 0.04 12.0 0.1 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Peptidase_A8 PF01252.13 CBZ28520.1 - 0.098 12.2 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 Signal peptidase (SPase) II DUF423 PF04241.10 CBZ28521.1 - 2.2e-23 81.9 3.7 2.2e-23 81.9 2.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF423) DUF1212 PF06738.7 CBZ28521.1 - 0.081 12.3 1.0 0.14 11.5 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) YrhK PF14145.1 CBZ28521.1 - 0.095 12.3 0.2 0.22 11.2 0.1 1.7 1 0 0 1 1 1 0 YrhK-like protein MerC PF03203.9 CBZ28521.1 - 0.48 10.7 4.0 11 6.3 2.7 2.2 1 1 0 1 1 1 0 MerC mercury resistance protein DUF95 PF01944.12 CBZ28521.1 - 4 7.0 7.2 8.9 5.9 0.9 2.1 1 1 1 2 2 2 0 Integral membrane protein DUF95 Gly-rich_Ago1 PF12764.2 CBZ28522.1 - 0.062 13.9 6.7 0.12 13.0 4.6 1.5 1 0 0 1 1 1 0 Glycine-rich region of argonaut Reo_sigmaC PF04582.7 CBZ28523.1 - 9.2 5.3 20.9 2.8 7.0 0.4 4.2 2 1 2 4 4 4 0 Reovirus sigma C capsid protein DEAD PF00270.24 CBZ28524.1 - 1.2e-41 141.9 0.0 1.1e-39 135.6 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ28524.1 - 4.3e-27 93.7 0.1 9.8e-27 92.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CBZ28524.1 - 0.0036 17.0 0.5 0.013 15.2 0.0 2.2 2 1 1 3 3 3 1 Part of AAA domain CMS1 PF14617.1 CBZ28524.1 - 0.0037 16.3 0.0 0.0089 15.1 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 CBZ28524.1 - 0.04 14.0 0.1 0.16 12.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain Coa1 PF08695.5 CBZ28526.1 - 0.009 15.5 0.0 0.026 14.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 CoA_binding_3 PF13727.1 CBZ28526.1 - 0.016 15.0 0.4 0.023 14.5 0.3 1.2 1 0 0 1 1 1 0 CoA-binding domain Abhydrolase_6 PF12697.2 CBZ28528.1 - 3e-28 99.2 0.2 4e-28 98.8 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ28528.1 - 3.3e-18 66.0 0.0 5.7e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CBZ28528.1 - 1.3e-15 57.4 0.0 2.3e-15 56.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ28528.1 - 0.00032 19.9 0.2 0.2 10.8 0.0 3.0 3 1 1 4 4 4 1 Prolyl oligopeptidase family Ndr PF03096.9 CBZ28528.1 - 0.0019 16.7 0.1 0.0046 15.4 0.1 1.6 1 1 0 1 1 1 1 Ndr family Abhydrolase_2 PF02230.11 CBZ28528.1 - 0.0029 17.0 0.0 0.037 13.4 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 CBZ28528.1 - 0.0052 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 CBZ28528.1 - 0.0092 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 CBZ28528.1 - 0.0095 15.3 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 CBZ28528.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase_phd PF10503.4 CBZ28528.1 - 0.085 12.0 0.5 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Esterase PF00756.15 CBZ28528.1 - 0.092 12.1 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DLH PF01738.13 CBZ28528.1 - 0.096 11.9 0.0 3.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family TPP_enzyme_N PF02776.13 CBZ28529.1 - 7.7e-15 54.8 1.8 4.3e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CBZ28529.1 - 6.5e-10 38.7 3.2 9.8e-09 34.9 0.6 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Kelch_3 PF13415.1 CBZ28530.1 - 9.5e-16 57.4 5.0 8.2e-07 29.0 0.0 4.1 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CBZ28530.1 - 4.8e-14 51.8 0.1 3.1e-05 23.9 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 CBZ28530.1 - 8.7e-14 51.0 0.5 4.8e-06 26.2 0.0 3.9 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ28530.1 - 6.8e-13 48.2 0.1 1.9e-06 27.7 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CBZ28530.1 - 4e-10 39.0 1.5 0.0015 18.2 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 CBZ28530.1 - 9.2e-09 34.7 0.4 0.00069 19.1 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Helicase_C_2 PF13307.1 CBZ28531.1 - 6.6e-44 149.7 0.0 1.1e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 CBZ28531.1 - 3.5e-35 120.9 0.0 5.3e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 CBZ28531.1 - 0.00047 19.6 0.0 0.22 11.0 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CBZ28531.1 - 0.0011 18.8 0.0 0.44 10.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit TruD PF01142.13 CBZ28533.1 - 3.2e-42 144.5 0.0 5.8e-40 137.1 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF3342 PF11822.3 CBZ28534.1 - 2.5e-134 447.4 0.0 3.1e-134 447.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Pkinase PF00069.20 CBZ28536.1 - 0.0084 15.2 0.0 0.98 8.5 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase PF00069.20 CBZ28538.1 - 5.3e-63 212.5 0.0 7.5e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28538.1 - 4.3e-33 114.4 0.0 6.6e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Lipocalin_5 PF13924.1 CBZ28538.1 - 8.6e-27 93.5 0.0 2e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Lipocalin-like domain PX PF00787.19 CBZ28538.1 - 1.1e-14 54.1 0.1 2.3e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.1 CBZ28538.1 - 9.6e-06 24.7 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ28538.1 - 0.00011 22.0 2.9 0.0032 17.2 0.2 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family FYVE PF01363.16 CBZ28538.1 - 0.00011 21.9 1.2 0.00033 20.4 0.9 1.8 1 0 0 1 1 1 1 FYVE zinc finger Sulfate_transp PF00916.15 CBZ28539.1 - 1.4e-34 119.4 10.3 2.4e-34 118.6 7.1 1.4 1 0 0 1 1 1 1 Sulfate transporter family His_Phos_2 PF00328.17 CBZ28539.1 - 3e-16 59.6 0.3 1.9e-14 53.7 0.0 2.5 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 2) Sulfate_tra_GLY PF13792.1 CBZ28539.1 - 2.1e-14 52.9 5.2 6.3e-14 51.4 3.6 1.8 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CBZ28539.1 - 5.1e-08 32.3 0.0 9.8e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain Amidase_2 PF01510.20 CBZ28539.1 - 0.021 14.8 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase zf-HIT PF04438.11 CBZ28540.1 - 0.32 10.6 7.3 0.75 9.4 5.0 1.6 1 0 0 1 1 1 0 HIT zinc finger Glu-tRNAGln PF02686.10 CBZ28541.1 - 0.21 11.3 0.9 19 5.1 0.0 3.0 3 0 0 3 3 3 0 Glu-tRNAGln amidotransferase C subunit HEAT_2 PF13646.1 CBZ28543.1 - 2.7e-15 56.4 2.7 4.8e-09 36.3 0.0 4.6 3 1 1 4 4 4 2 HEAT repeats PC_rep PF01851.17 CBZ28543.1 - 5.6e-15 54.6 10.2 0.053 13.7 0.0 8.3 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT PF02985.17 CBZ28543.1 - 0.0025 17.7 4.6 30 5.0 0.0 5.5 5 0 0 5 5 5 0 HEAT repeat TPR_8 PF13181.1 CBZ28543.1 - 0.0033 17.0 1.0 15 5.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TIM-br_sig_trns PF09370.5 CBZ28543.1 - 0.047 12.7 0.5 0.087 11.8 0.4 1.3 1 0 0 1 1 1 0 TIM-barrel signal transduction protein TPR_16 PF13432.1 CBZ28543.1 - 0.052 14.2 0.9 23 5.8 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ28543.1 - 0.13 12.1 4.0 6.8 6.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ28543.1 - 0.22 12.0 6.9 3.6 8.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Nol1_Nop2_Fmu PF01189.12 CBZ28544.1 - 2.6e-18 66.4 0.0 4.2e-08 32.8 0.0 2.6 2 1 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CBZ28544.1 - 0.0014 18.6 0.2 0.0049 16.8 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ28544.1 - 0.012 16.2 0.2 0.072 13.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DNA_binding_2 PF13724.1 CBZ28544.1 - 0.044 13.9 0.1 0.41 10.8 0.0 2.6 2 0 0 2 2 2 0 DNA-binding domain Methyltransf_30 PF05430.6 CBZ28545.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.20 CBZ28546.1 - 2.3e-15 56.4 0.0 4.2e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 CBZ28546.1 - 2.2e-07 30.5 7.6 0.0034 17.2 0.2 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 CBZ28546.1 - 0.00025 20.2 0.0 0.00043 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28546.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 CBZ28546.1 - 0.48 9.7 0.0 0.8 9.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 CBZ28546.1 - 0.87 8.3 0.1 1.3 7.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ArfGap PF01412.13 CBZ28547.1 - 1.1e-13 50.9 0.1 1.6e-13 50.4 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Topoisom_bac PF01131.15 CBZ28548.1 - 4.2e-100 335.4 0.0 5.3e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CBZ28548.1 - 3.7e-16 58.9 0.0 6.5e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Toprim domain AAA PF00004.24 CBZ28549.1 - 4.6e-32 110.9 0.0 6.9e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ28549.1 - 3.3e-07 30.4 0.0 6.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ28549.1 - 4e-07 30.4 0.0 6.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ28549.1 - 1.8e-06 28.7 0.0 3.4e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ28549.1 - 3.3e-06 27.0 0.0 9e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ28549.1 - 2.4e-05 24.4 0.0 5.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 CBZ28549.1 - 0.0005 19.5 0.0 0.0015 17.9 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.17 CBZ28549.1 - 0.00091 19.3 0.0 0.0031 17.6 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 CBZ28549.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ28549.1 - 0.0018 17.9 0.0 0.0043 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBZ28549.1 - 0.003 16.9 0.4 0.1 11.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CBZ28549.1 - 0.0038 16.3 0.0 0.007 15.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CBZ28549.1 - 0.0067 16.1 0.0 0.032 13.9 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 CBZ28549.1 - 0.0082 15.7 0.0 0.014 14.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 CBZ28549.1 - 0.012 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 CBZ28549.1 - 0.014 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_11 PF13086.1 CBZ28549.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CBZ28549.1 - 0.048 13.3 0.0 0.095 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CBZ28549.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_2 PF07724.9 CBZ28549.1 - 0.084 12.7 0.0 0.35 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 CBZ28549.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_30 PF13604.1 CBZ28549.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBZ28549.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CBZ28549.1 - 0.18 11.2 0.1 0.55 9.7 0.0 1.8 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 CBZ28549.1 - 0.24 11.6 0.0 0.37 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3597 PF12200.3 CBZ28551.1 - 0.2 12.0 2.4 0.37 11.1 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Rep_fac-A_C PF08646.5 CBZ28552.1 - 3.4e-42 143.6 1.0 1.8e-40 138.0 0.1 2.8 3 0 0 3 3 3 1 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CBZ28552.1 - 1.7e-13 50.2 0.5 5.6e-10 38.9 0.0 2.9 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain DZR PF12773.2 CBZ28552.1 - 0.052 13.3 2.5 0.098 12.4 1.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon Nairovirus_M PF07948.6 CBZ28552.1 - 0.15 10.1 0.3 0.37 8.8 0.0 1.7 2 0 0 2 2 2 0 Nairovirus M polyprotein-like zinc-ribbons_6 PF07191.7 CBZ28552.1 - 0.17 11.7 1.7 0.32 10.8 1.2 1.4 1 0 0 1 1 1 0 zinc-ribbons OrfB_Zn_ribbon PF07282.6 CBZ28552.1 - 0.72 9.5 2.8 1.5 8.5 1.9 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SNF2_N PF00176.18 CBZ28553.1 - 1.1e-55 188.5 0.0 2.7e-55 187.2 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CBZ28553.1 - 1e-09 38.0 10.5 1e-09 38.0 7.3 2.4 2 0 0 2 2 2 1 Ring finger domain Helicase_C PF00271.26 CBZ28553.1 - 1.2e-09 37.8 0.0 2.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 CBZ28553.1 - 2.8e-09 36.5 9.4 6.7e-09 35.2 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ28553.1 - 3.3e-09 36.6 10.9 3.3e-09 36.6 7.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ28553.1 - 2.7e-08 33.3 10.6 2.7e-08 33.3 7.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ28553.1 - 2.9e-07 30.0 9.1 7.7e-07 28.7 6.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 CBZ28553.1 - 0.0003 20.6 0.0 0.00059 19.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.1 CBZ28553.1 - 0.0003 20.4 9.3 0.00072 19.2 6.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CBZ28553.1 - 0.00038 20.2 9.5 0.0011 18.8 6.6 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 CBZ28553.1 - 0.026 14.0 3.7 0.069 12.6 2.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CBZ28553.1 - 0.08 12.7 3.6 0.23 11.2 2.5 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 CBZ28553.1 - 0.12 11.9 7.3 0.28 10.7 5.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CBZ28553.1 - 0.3 11.2 11.8 0.073 13.1 5.3 2.2 2 1 0 2 2 1 0 RING-H2 zinc finger Aldolase_II PF00596.16 CBZ28554.1 - 1.9e-39 135.1 0.0 2.2e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Kinesin PF00225.18 CBZ28555.1 - 1.2e-86 290.5 0.2 1.7e-86 289.9 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 CBZ28555.1 - 0.17 11.9 0.8 0.56 10.3 0.1 2.3 2 1 0 2 2 2 0 AAA domain RPA_interact_M PF14767.1 CBZ28555.1 - 0.32 11.7 7.5 2.2 9.0 0.1 2.9 3 0 0 3 3 3 0 Replication protein A interacting middle DUF904 PF06005.7 CBZ28555.1 - 0.97 9.7 14.3 2.5 8.4 0.4 3.5 2 1 0 3 3 3 0 Protein of unknown function (DUF904) DUF4586 PF15239.1 CBZ28556.1 - 6.6e-44 150.6 2.7 8.1e-44 150.3 1.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Methyltransf_16 PF10294.4 CBZ28557.1 - 2.6e-14 53.0 0.8 6.1e-11 42.0 0.3 3.2 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 CBZ28557.1 - 0.0012 19.4 0.0 0.0027 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF663 PF04950.7 CBZ28558.1 - 1.8e-71 240.5 0.0 2.8e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CBZ28558.1 - 2.8e-24 84.4 0.0 1.1e-23 82.6 0.0 2.1 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_16 PF13191.1 CBZ28558.1 - 0.00011 22.2 0.0 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBZ28558.1 - 0.00015 21.9 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CBZ28558.1 - 0.00019 21.1 0.0 0.00052 19.7 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 CBZ28558.1 - 0.00027 20.4 0.0 0.012 15.0 0.0 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.24 CBZ28558.1 - 0.0018 18.4 0.0 0.0052 16.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 CBZ28558.1 - 0.0039 17.1 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CBZ28558.1 - 0.0076 16.5 0.1 0.05 13.9 0.0 2.3 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 CBZ28558.1 - 0.0097 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 CBZ28558.1 - 0.011 15.5 1.7 0.022 14.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CBZ28558.1 - 0.012 15.3 0.2 0.034 13.9 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 CBZ28558.1 - 0.016 14.9 0.0 0.071 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ28558.1 - 0.017 15.9 0.0 0.017 15.9 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_10 PF12846.2 CBZ28558.1 - 0.021 14.2 0.5 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 CBZ28558.1 - 0.022 14.4 0.1 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.12 CBZ28558.1 - 0.025 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein cobW PF02492.14 CBZ28558.1 - 0.036 13.4 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 CBZ28558.1 - 0.044 14.2 0.0 0.13 12.7 0.0 1.8 2 0 0 2 2 1 0 Miro-like protein NB-ARC PF00931.17 CBZ28558.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF258 PF03193.11 CBZ28558.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CBZ28558.1 - 0.14 11.8 0.0 0.14 11.8 0.0 2.0 3 0 0 3 3 2 0 Archaeal ATPase Viral_helicase1 PF01443.13 CBZ28558.1 - 0.16 11.4 0.1 0.75 9.2 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 CBZ28558.1 - 0.63 10.3 4.8 9.5 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain zf-DHHC PF01529.15 CBZ28559.1 - 3.9e-28 98.0 0.5 3.9e-28 98.0 0.4 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase IF-2B PF01008.12 CBZ28559.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family DnaJ PF00226.26 CBZ28560.1 - 3.7e-09 36.2 0.0 7.4e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain SBDS_C PF09377.5 CBZ28560.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 SBDS protein C-terminal domain BCIP PF13862.1 CBZ28561.1 - 1.4e-22 80.1 0.0 2.1e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein dsDNA_bind PF01984.15 CBZ28562.1 - 4.9e-23 81.1 13.1 5.5e-23 81.0 9.1 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain UPF0154 PF03672.8 CBZ28562.1 - 0.14 11.8 0.1 0.14 11.8 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DUF1749 PF08538.5 CBZ28562.1 - 0.78 8.5 3.6 0.64 8.8 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) LKAAEAR PF15478.1 CBZ28562.1 - 0.89 9.8 10.2 2.7 8.2 5.0 2.0 1 1 1 2 2 2 0 Family of unknown function with LKAAEAR motif YlqD PF11068.3 CBZ28562.1 - 3.8 7.5 12.6 4.7 7.2 8.5 1.4 1 1 0 1 1 1 0 YlqD protein DUF2870 PF11069.3 CBZ28562.1 - 5.3 7.1 7.3 7.4 6.6 3.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2870) LTXXQ PF07813.7 CBZ28562.1 - 5.8 7.4 17.0 7.2 7.1 7.7 2.1 1 1 1 2 2 2 0 LTXXQ motif family protein Zip PF02535.17 CBZ28563.1 - 4.8e-36 124.3 11.9 4.8e-36 124.3 8.2 1.9 2 0 0 2 2 2 1 ZIP Zinc transporter CorA PF01544.13 CBZ28564.1 - 1.5 7.8 11.6 0.089 11.8 3.7 2.1 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein Peptidase_S15 PF02129.13 CBZ28565.1 - 5.9e-57 193.1 0.0 2.7e-56 190.9 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 CBZ28565.1 - 3.9e-32 111.9 0.0 5.8e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 CBZ28565.1 - 2.2e-13 50.6 0.2 4.2e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ28565.1 - 5.2e-11 42.4 0.1 1.2e-09 38.0 0.0 2.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ28565.1 - 2.5e-06 26.8 0.8 1.6e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 CBZ28565.1 - 0.0046 15.5 0.0 0.013 14.0 0.0 1.7 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 CBZ28565.1 - 0.017 14.6 0.1 0.063 12.8 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 CBZ28565.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family GTP_EFTU PF00009.22 CBZ28566.1 - 2.2e-40 138.1 0.0 4.3e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CBZ28566.1 - 3.1e-20 71.7 0.0 6.5e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CBZ28566.1 - 8.1e-12 44.8 0.1 1.9e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CBZ28566.1 - 7e-06 26.0 0.0 2.3e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ28566.1 - 0.0095 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.13 CBZ28566.1 - 0.01 15.3 0.0 0.043 13.3 0.0 2.0 2 0 0 2 2 2 0 Elongation factor G, domain IV AIG1 PF04548.11 CBZ28566.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family FeoB_N PF02421.13 CBZ28566.1 - 0.033 13.4 0.0 0.12 11.6 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.5 CBZ28566.1 - 0.059 12.5 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit LacAB_rpiB PF02502.13 CBZ28567.1 - 7.8e-50 168.1 0.1 9.4e-50 167.9 0.1 1.1 1 0 0 1 1 1 1 Ribose/Galactose Isomerase LRR_6 PF13516.1 CBZ28569.1 - 1e-18 65.2 1.1 0.081 13.0 0.0 7.7 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.2 CBZ28569.1 - 7.5e-09 35.0 2.7 0.021 14.4 0.1 5.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ28569.1 - 5e-07 28.8 2.5 0.78 10.0 0.0 6.6 7 0 0 7 7 7 2 Leucine Rich Repeat GP41 PF00517.12 CBZ28569.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Retroviral envelope protein LRR_8 PF13855.1 CBZ28569.1 - 0.11 12.2 11.1 0.87 9.3 0.4 4.7 2 2 3 5 5 5 0 Leucine rich repeat LRR_7 PF13504.1 CBZ28569.1 - 1.2 9.6 14.5 3.3 8.3 0.0 6.0 7 0 0 7 7 7 0 Leucine rich repeat DUF4282 PF14110.1 CBZ28570.1 - 0.063 13.4 4.6 0.11 12.7 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DuoxA PF10204.4 CBZ28570.1 - 0.18 10.8 2.8 0.21 10.6 1.9 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor DUF2422 PF10337.4 CBZ28570.1 - 0.23 10.1 4.6 0.24 10.1 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Pkinase PF00069.20 CBZ28571.1 - 7.7e-55 185.8 0.0 2.5e-54 184.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28571.1 - 1.1e-25 90.2 0.0 1.5e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28571.1 - 0.00065 18.7 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CBZ28571.1 - 0.0024 17.6 0.1 0.054 13.2 0.1 2.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family StbA PF06406.6 CBZ28571.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 StbA protein Choline_kinase PF01633.15 CBZ28571.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 CBZ28571.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 CBZ28571.1 - 0.21 10.6 0.0 0.48 9.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family D123 PF07065.9 CBZ28572.1 - 0.033 13.2 0.0 0.086 11.9 0.0 1.6 2 0 0 2 2 2 0 D123 Matrilin_ccoil PF10393.4 CBZ28573.1 - 0.75 9.2 7.7 2.6 7.4 0.8 3.0 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin GRIM-19 PF06212.7 CBZ28574.1 - 1.4e-08 34.4 0.0 1.7e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 GRIM-19 protein DPCD PF14913.1 CBZ28575.1 - 5.2e-54 182.3 0.0 5.9e-54 182.1 0.0 1.0 1 0 0 1 1 1 1 DPCD protein family AMP-binding PF00501.23 CBZ28576.1 - 1.9e-34 118.7 0.0 1.3e-33 115.9 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Ank_2 PF12796.2 CBZ28576.1 - 3.3e-17 62.6 4.7 7.9e-10 38.9 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ28576.1 - 3.3e-13 49.7 0.6 4.2e-07 30.3 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 CBZ28576.1 - 1.1e-12 47.1 4.6 0.00028 20.5 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CBZ28576.1 - 2.1e-09 37.2 8.5 1e-05 25.6 0.2 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ28576.1 - 5.6e-09 35.3 4.5 1.3 9.4 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat AMP-binding_C PF13193.1 CBZ28576.1 - 4.7e-05 24.2 0.0 0.00014 22.6 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 CBZ28576.1 - 0.041 14.1 0.0 0.14 12.3 0.0 2.0 1 0 0 1 1 1 0 Phosphopantetheine attachment site RNA_pol_L_2 PF13656.1 CBZ28577.1 - 1.4e-22 78.8 0.0 2.1e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CBZ28577.1 - 0.0015 17.6 0.0 0.0025 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Gemini_AL1 PF00799.15 CBZ28577.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Sua5_yciO_yrdC PF01300.13 CBZ28578.1 - 2e-45 154.2 0.0 2.7e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CBZ28578.1 - 1.2e-08 35.0 0.0 2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DEAD PF00270.24 CBZ28579.1 - 2.9e-42 144.0 0.0 4.3e-41 140.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ28579.1 - 2.7e-23 81.6 0.3 5.2e-23 80.7 0.2 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ28579.1 - 7.6e-06 25.8 0.0 1.6e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CBZ28579.1 - 0.0056 16.4 0.6 0.024 14.3 0.1 2.3 3 0 0 3 3 3 1 Part of AAA domain T4SS-DNA_transf PF02534.9 CBZ28579.1 - 0.013 14.0 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer PhoH PF02562.11 CBZ28579.1 - 0.036 13.2 0.0 4 6.6 0.0 2.9 2 1 1 3 3 3 0 PhoH-like protein CEP76-C2 PF15627.1 CBZ28580.1 - 1.4e-41 141.5 0.0 2.3e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 CEP76 C2 domain Transglut_core PF01841.14 CBZ28580.1 - 0.11 12.7 0.0 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily C2 PF00168.25 CBZ28580.1 - 0.13 12.0 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 C2 domain UPF0220 PF05255.6 CBZ28581.1 - 4.4e-16 58.5 0.5 4.7e-16 58.4 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) SUR7 PF06687.7 CBZ28581.1 - 0.09 12.3 4.2 0.077 12.5 2.2 1.4 1 1 0 1 1 1 0 SUR7/PalI family DUF4131 PF13567.1 CBZ28581.1 - 0.68 9.3 5.2 0.13 11.6 0.2 2.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) GDPD PF03009.12 CBZ28582.1 - 1.9e-19 70.1 0.0 6.2e-17 61.9 0.0 2.2 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Cullin PF00888.17 CBZ28583.1 - 1.2e-42 146.2 2.9 1.7e-42 145.7 2.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBZ28583.1 - 3.3e-12 46.0 0.6 1.7e-11 43.8 0.0 2.6 3 0 0 3 3 3 1 Cullin protein neddylation domain TrmB PF01978.14 CBZ28583.1 - 0.0082 15.8 0.5 0.094 12.4 0.0 2.6 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Penicillinase_R PF03965.11 CBZ28583.1 - 0.019 15.0 0.0 0.084 12.9 0.0 2.1 1 0 0 1 1 1 0 Penicillinase repressor Cullin PF00888.17 CBZ28584.1 - 7.1e-30 104.1 0.0 1e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CBZ28584.1 - 7.7e-07 28.8 1.1 2.6e-06 27.1 0.1 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 CBZ28584.1 - 0.00069 19.6 0.3 0.0028 17.7 0.0 2.2 2 0 0 2 2 2 1 Penicillinase repressor HTH_20 PF12840.2 CBZ28584.1 - 0.09 12.5 0.9 20 5.0 0.1 3.2 4 0 0 4 4 4 0 Helix-turn-helix domain MarR_2 PF12802.2 CBZ28584.1 - 0.11 12.2 0.2 2.9 7.6 0.1 2.6 2 0 0 2 2 2 0 MarR family Dynein_light PF01221.13 CBZ28585.1 - 1.6e-32 111.3 0.0 1.8e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CBZ28585.1 - 0.032 14.5 0.0 0.045 14.0 0.0 1.3 1 1 0 1 1 1 0 Ground-like domain TINF2_N PF14973.1 CBZ28585.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus HhH-GPD PF00730.20 CBZ28586.1 - 9.2e-19 67.7 0.0 5.4e-18 65.2 0.0 2.3 3 0 0 3 3 3 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 CBZ28586.1 - 1.6e-12 46.8 0.0 8.1e-12 44.5 0.0 2.2 3 0 0 3 3 3 1 NUDIX domain HHH PF00633.18 CBZ28586.1 - 1.3e-05 24.5 0.1 4.4e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.2 CBZ28586.1 - 0.031 14.1 0.0 7.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.1 CBZ28586.1 - 0.083 13.0 0.1 4.2 7.6 0.0 2.8 2 1 0 2 2 2 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 CBZ28586.1 - 1.1 9.5 6.4 3.3 8.0 4.5 1.8 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Kelch_3 PF13415.1 CBZ28587.1 - 1.4e-10 41.0 1.0 0.00013 22.0 0.0 3.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CBZ28587.1 - 3.2e-09 36.5 0.1 0.0016 18.5 0.0 3.8 2 1 1 3 3 3 2 Kelch motif Kelch_4 PF13418.1 CBZ28587.1 - 8e-09 35.1 0.0 8.5e-06 25.4 0.0 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_5 PF13854.1 CBZ28587.1 - 7.8e-06 25.7 0.0 0.0002 21.2 0.0 3.0 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 CBZ28587.1 - 0.0002 20.9 3.0 0.00026 20.6 0.0 2.8 3 0 0 3 3 3 1 Kelch motif APS-reductase_C PF12139.3 CBZ28587.1 - 0.01 15.9 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit Methyltransf_11 PF08241.7 CBZ28588.1 - 2.4e-07 31.1 0.0 5.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ28588.1 - 1.4e-06 28.8 0.0 2.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ28588.1 - 1.8e-05 25.1 0.0 3.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ28588.1 - 3.2e-05 23.5 0.0 4.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain BMC PF00936.14 CBZ28588.1 - 0.068 12.8 0.2 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 BMC domain Sel1 PF08238.7 CBZ28589.1 - 0.0079 16.8 6.9 0.55 10.9 0.1 3.5 4 0 0 4 4 4 2 Sel1 repeat DLIC PF05783.6 CBZ28589.1 - 0.093 11.3 2.6 0.21 10.2 1.8 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) YARHG PF13308.1 CBZ28590.1 - 0.096 12.2 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 YARHG domain Prp19 PF08606.6 CBZ28591.1 - 0.0091 15.7 0.3 0.0091 15.7 0.2 2.2 2 0 0 2 2 2 1 Prp19/Pso4-like Sipho_Gp157 PF05565.6 CBZ28591.1 - 0.08 12.5 2.1 4.1 6.9 0.4 2.3 2 0 0 2 2 2 0 Siphovirus Gp157 Mnd1 PF03962.10 CBZ28591.1 - 1.2 8.7 12.9 1.3 8.6 2.7 2.5 2 0 0 2 2 2 0 Mnd1 family HALZ PF02183.13 CBZ28591.1 - 1.3 8.7 5.5 0.66 9.7 0.9 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper LsmAD PF06741.8 CBZ28591.1 - 2.1 8.4 4.6 2.3 8.3 0.2 2.5 2 0 0 2 2 2 0 LsmAD domain DUF4618 PF15397.1 CBZ28591.1 - 8.3 5.6 10.5 16 4.6 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) GAS PF13851.1 CBZ28591.1 - 9.3 5.3 15.9 0.43 9.7 3.4 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Glyco_hydro_63 PF03200.11 CBZ28592.1 - 2.6e-63 214.1 0.0 2.2e-60 204.4 0.0 2.1 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Ribosomal_S14 PF00253.16 CBZ28593.1 - 2.3e-16 58.9 3.4 2.4e-16 58.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L40e PF01020.12 CBZ28593.1 - 0.052 13.1 2.2 0.42 10.2 0.5 2.2 2 0 0 2 2 2 0 Ribosomal L40e family PhosphMutase PF10143.4 CBZ28595.1 - 8.9e-58 194.7 0.0 1.5e-57 193.9 0.0 1.4 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 CBZ28595.1 - 3.1e-16 59.5 0.0 3.3e-15 56.1 0.0 2.3 1 1 0 1 1 1 1 Metalloenzyme superfamily AIG2 PF06094.7 CBZ28595.1 - 1.5e-11 44.6 0.0 5.4e-11 42.8 0.0 2.0 1 1 0 1 1 1 1 AIG2-like family Cyclin_N PF00134.18 CBZ28596.1 - 0.00072 19.1 0.2 0.0015 18.1 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Type_III_YscX PF09474.5 CBZ28596.1 - 0.072 13.1 0.1 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) BCL9 PF11502.3 CBZ28596.1 - 1.7 8.2 6.8 4.5 6.8 4.7 1.7 1 0 0 1 1 1 0 B-cell lymphoma 9 protein PEX11 PF05648.9 CBZ28598.1 - 1.1e-05 24.8 3.0 1.7e-05 24.2 2.1 1.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.9 CBZ28599.1 - 2.9e-20 72.5 1.5 5e-20 71.7 1.1 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MOZ_SAS PF01853.13 CBZ28600.1 - 3.3e-36 124.3 0.1 4.2e-20 71.7 0.2 3.0 3 0 0 3 3 3 2 MOZ/SAS family DNA_topoisoIV PF00521.15 CBZ28601.1 - 1.8e-129 432.3 0.0 2.8e-129 431.7 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CBZ28601.1 - 8.6e-30 103.2 0.1 2.1e-29 101.9 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.21 CBZ28601.1 - 6.7e-10 38.6 0.0 2e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.17 CBZ28601.1 - 1.2e-08 34.7 0.0 4.5e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Toprim domain Pap_E4 PF02711.9 CBZ28601.1 - 1.4 9.7 22.7 3.8 8.3 2.9 3.9 3 0 0 3 3 3 0 E4 protein Hexapep PF00132.19 CBZ28602.1 - 6.2e-07 28.6 2.8 0.12 11.9 0.2 4.0 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBZ28602.1 - 0.00032 20.1 3.7 0.06 12.9 0.1 3.5 1 1 2 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 CBZ28602.1 - 0.024 13.9 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyl transferase Cep57_MT_bd PF06657.8 CBZ28603.1 - 0.35 10.8 8.3 1.3 8.9 0.0 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 UPF0184 PF03670.8 CBZ28603.1 - 3.6 7.8 5.8 1.6 8.9 1.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) eIF3_N PF09440.5 CBZ28604.1 - 3.4e-28 98.4 2.1 6.8e-28 97.4 1.5 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 CBZ28604.1 - 2.6e-09 37.3 0.5 9.2e-09 35.5 0.2 2.0 2 0 0 2 2 2 1 PCI domain TPR_3 PF07720.7 CBZ28604.1 - 0.076 12.8 1.5 0.21 11.4 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CactinC_cactus PF09732.4 CBZ28606.1 - 9.1e-40 135.1 1.4 1.6e-39 134.3 1.0 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SHMT PF00464.14 CBZ28609.1 - 7.8e-174 577.7 0.0 9.8e-174 577.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CBZ28609.1 - 0.0071 15.5 0.0 0.0089 15.2 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Laminin_EGF PF00053.19 CBZ28610.1 - 0.0028 17.5 12.9 0.0028 17.5 8.9 7.9 4 3 3 7 7 7 4 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 CBZ28610.1 - 0.0076 16.3 14.4 0.0076 16.3 10.0 9.5 7 2 2 9 9 9 3 EGF-like domain MCM PF00493.18 CBZ28611.1 - 8.3e-121 402.8 0.4 1.2e-120 402.3 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBZ28611.1 - 2.4e-08 34.4 0.0 6.2e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBZ28611.1 - 6.6e-07 28.6 0.0 3.6e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBZ28611.1 - 0.00043 20.0 0.2 0.0033 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CBZ28611.1 - 0.0071 15.8 0.1 0.021 14.2 0.1 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 CBZ28611.1 - 0.0084 15.7 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) WW PF00397.21 CBZ28612.1 - 2e-09 37.1 0.7 4e-09 36.1 0.5 1.5 1 0 0 1 1 1 1 WW domain Bunya_RdRp PF04196.7 CBZ28612.1 - 0.019 12.9 1.0 0.03 12.3 0.7 1.2 1 0 0 1 1 1 0 Bunyavirus RNA dependent RNA polymerase PsaD PF02531.11 CBZ28612.1 - 0.029 13.5 0.0 0.075 12.2 0.0 1.6 1 0 0 1 1 1 0 PsaD GCD14 PF08704.5 CBZ28613.1 - 5.2e-63 212.8 1.0 6e-37 127.4 0.0 3.7 2 1 2 4 4 4 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 CBZ28613.1 - 1.8e-09 37.3 0.0 4e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ28613.1 - 3.6e-06 26.9 0.5 1.2e-05 25.2 0.3 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBZ28613.1 - 5.1e-05 22.9 0.0 0.00017 21.2 0.0 1.9 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 CBZ28613.1 - 0.00033 21.0 0.0 0.0027 18.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CBZ28613.1 - 0.00063 20.5 0.3 0.0017 19.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ28613.1 - 0.0012 19.3 0.0 0.0027 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.12 CBZ28613.1 - 0.0013 17.7 0.0 0.21 10.4 0.0 2.2 2 0 0 2 2 2 2 Fibrillarin Methyltransf_12 PF08242.7 CBZ28613.1 - 0.0095 16.3 0.1 0.13 12.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ28613.1 - 0.014 14.8 0.0 0.059 12.7 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase small domain RrnaAD PF00398.15 CBZ28613.1 - 0.021 13.8 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 CBZ28613.1 - 0.024 13.7 0.0 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 CBZ28613.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Rft-1 PF04506.8 CBZ28614.1 - 8.3e-24 83.8 4.9 4.7e-21 74.7 1.3 2.5 2 0 0 2 2 2 2 Rft protein Herpes_ICP4_N PF03584.10 CBZ28614.1 - 0.033 13.6 0.1 0.087 12.3 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region 2-oxoacid_dh PF00198.18 CBZ28615.1 - 1.1e-80 270.1 0.3 1.4e-80 269.8 0.2 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CBZ28615.1 - 1e-19 69.9 1.6 1.7e-19 69.1 1.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 CBZ28615.1 - 2.4e-05 23.9 0.4 0.12 12.0 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.14 CBZ28615.1 - 0.00036 20.2 0.4 0.00068 19.3 0.3 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD PF00529.15 CBZ28615.1 - 0.00038 19.8 0.3 0.005 16.1 0.0 2.1 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 CBZ28615.1 - 0.013 14.7 0.1 2 7.4 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein HlyD_3 PF13437.1 CBZ28615.1 - 0.1 12.9 0.5 7 7.0 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein Hc1 PF07432.8 CBZ28615.1 - 5.1 7.3 10.4 11 6.2 7.2 1.5 1 0 0 1 1 1 0 Histone H1-like protein Hc1 ATP-synt_ab PF00006.20 CBZ28616.1 - 4.6e-61 206.0 0.0 5.9e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBZ28616.1 - 3.4e-15 56.4 0.0 6.6e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBZ28616.1 - 4.1e-13 49.3 0.6 8.1e-13 48.3 0.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Hexapep PF00132.19 CBZ28617.1 - 0.00028 20.2 12.7 0.093 12.2 3.5 3.9 2 1 2 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 CBZ28617.1 - 0.0006 19.1 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CBZ28617.1 - 0.013 15.6 0.0 0.12 12.4 0.0 2.3 1 1 0 1 1 1 0 MobA-like NTP transferase domain Fucokinase PF07959.7 CBZ28617.1 - 0.031 12.8 0.3 0.052 12.1 0.2 1.3 1 0 0 1 1 1 0 L-fucokinase DUF676 PF05057.9 CBZ28618.1 - 1.2e-14 54.1 0.0 1.3e-13 50.7 0.0 2.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) FG-GAP PF01839.18 CBZ28619.1 - 8.6e-07 28.4 1.8 0.0038 16.8 0.0 4.5 4 0 0 4 4 4 2 FG-GAP repeat VCBS PF13517.1 CBZ28619.1 - 8.8e-06 25.9 0.1 1 9.7 0.0 4.9 4 1 1 5 5 5 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ribosomal_S14 PF00253.16 CBZ28620.1 - 2.3e-16 58.9 3.4 2.4e-16 58.8 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ribosomal_L40e PF01020.12 CBZ28620.1 - 0.052 13.1 2.2 0.42 10.2 0.5 2.2 2 0 0 2 2 2 0 Ribosomal L40e family ParA PF10609.4 CBZ28621.1 - 5.3e-36 122.3 0.0 9.5e-36 121.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CBZ28621.1 - 6.6e-18 64.8 0.0 9.5e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CBZ28621.1 - 1.7e-08 33.9 1.1 1.1e-07 31.2 0.8 1.9 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CBZ28621.1 - 2.5e-07 30.7 0.1 8.9e-07 28.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain Fer4_NifH PF00142.13 CBZ28621.1 - 4.8e-05 22.6 0.0 0.00049 19.3 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.6 CBZ28621.1 - 4.9e-05 22.5 0.2 0.0001 21.4 0.0 1.5 2 0 0 2 2 2 1 VirC1 protein ArsA_ATPase PF02374.10 CBZ28621.1 - 0.00016 20.8 0.7 0.0016 17.5 0.4 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase YhjQ PF06564.7 CBZ28621.1 - 0.042 13.2 0.2 0.28 10.4 0.0 1.9 2 0 0 2 2 2 0 YhjQ protein DUF1611 PF07755.6 CBZ28621.1 - 0.29 9.7 1.9 0.38 9.3 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1611) Sensor PF13796.1 CBZ28622.1 - 0.059 12.9 2.5 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Putative sensor Tetraspannin PF00335.15 CBZ28622.1 - 0.059 12.6 1.9 0.27 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetraspanin family Mucin PF01456.12 CBZ28622.1 - 0.099 12.4 4.1 0.18 11.5 1.5 2.3 2 1 0 2 2 2 0 Mucin-like glycoprotein IF4E PF01652.13 CBZ28624.1 - 7e-31 106.9 0.0 9.7e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E IBV_3C PF03620.8 CBZ28624.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 IBV 3C protein Acyl-CoA_dh_C PF12806.2 CBZ28625.1 - 2.5e-24 85.5 1.2 6.6e-24 84.2 0.8 1.7 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_1 PF00441.19 CBZ28625.1 - 3.3e-18 66.2 3.9 4.9e-17 62.4 2.7 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBZ28625.1 - 2e-15 56.0 0.0 5.3e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 CBZ28625.1 - 2.4e-12 47.4 0.1 6e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CBZ28625.1 - 1.5e-06 28.5 0.2 1.5e-06 28.5 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain R3H PF01424.17 CBZ28626.1 - 6.2e-11 41.8 0.3 1.4e-10 40.6 0.2 1.7 1 0 0 1 1 1 1 R3H domain PIF1 PF05970.9 CBZ28627.1 - 4.7e-29 101.4 0.0 1.1e-25 90.4 0.0 2.6 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 CBZ28627.1 - 8e-12 45.1 0.2 2.1e-11 43.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain UvrD_C_2 PF13538.1 CBZ28627.1 - 2.4e-05 24.3 0.0 6e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CBZ28627.1 - 0.00022 20.8 0.0 0.58 9.6 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CBZ28627.1 - 0.00048 19.8 3.2 0.00054 19.6 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 CBZ28627.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 CBZ28627.1 - 0.036 13.0 0.5 0.11 11.4 0.4 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 CBZ28627.1 - 0.043 13.2 0.8 0.71 9.2 0.9 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.11 CBZ28627.1 - 0.086 12.0 0.1 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.24 CBZ28627.1 - 0.092 12.9 0.0 0.35 11.0 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 CBZ28627.1 - 0.18 11.4 0.6 0.83 9.3 0.1 2.1 2 0 0 2 2 2 0 NTPase DEAD PF00270.24 CBZ28627.1 - 0.18 11.2 0.1 3.1 7.2 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ28627.1 - 0.19 11.8 1.0 2.6 8.2 0.7 2.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 CBZ28627.1 - 0.21 11.0 0.2 0.84 9.0 0.1 1.9 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UvrD-helicase PF00580.16 CBZ28627.1 - 0.21 10.8 0.0 0.4 9.9 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Herpes_Helicase PF02689.9 CBZ28627.1 - 0.35 8.5 1.4 6.9 4.2 0.0 2.5 2 1 0 2 2 2 0 Helicase DUF853 PF05872.7 CBZ28627.1 - 2.4 6.4 8.1 0.17 10.1 0.1 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) HEAT_2 PF13646.1 CBZ28628.1 - 7.7e-08 32.5 22.1 0.00011 22.4 0.8 6.7 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 CBZ28628.1 - 1.8e-05 24.4 18.5 0.0093 15.9 0.0 6.7 7 1 1 8 8 8 3 HEAT repeat TPR_2 PF07719.12 CBZ28629.1 - 2.4e-05 23.9 0.1 0.075 12.9 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ28629.1 - 0.0003 20.3 0.1 0.0017 17.9 0.1 2.4 2 1 0 2 2 2 1 TPR repeat zf-MYND PF01753.13 CBZ28629.1 - 0.0017 18.1 6.8 0.0017 18.1 4.7 2.5 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.1 CBZ28629.1 - 0.011 15.6 0.2 0.16 11.9 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat SET PF00856.23 CBZ28629.1 - 0.069 13.4 0.1 0.55 10.5 0.0 2.5 3 0 0 3 3 3 0 SET domain Ribosomal_S17e PF00833.13 CBZ28630.1 - 4.3e-51 171.7 3.5 5.4e-51 171.4 2.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S17e PF00833.13 CBZ28631.1 - 4.3e-51 171.7 3.5 5.4e-51 171.4 2.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 HEAT_2 PF13646.1 CBZ28633.1 - 3.6e-12 46.3 21.5 0.0013 18.9 2.7 7.0 3 3 2 6 6 6 3 HEAT repeats SF3b1 PF08920.5 CBZ28633.1 - 6.7e-08 32.6 0.0 1.3e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 UME PF08064.8 CBZ28633.1 - 3.9e-05 23.5 1.4 0.0071 16.2 0.0 4.1 5 0 0 5 5 4 1 UME (NUC010) domain RIX1 PF08167.7 CBZ28633.1 - 0.0074 15.9 0.0 2.4 7.7 0.0 3.3 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 CBZ28633.1 - 0.0096 14.2 0.9 2.5 6.3 0.1 2.7 2 1 0 2 2 2 2 Adaptin N terminal region MMS19_C PF12460.3 CBZ28633.1 - 0.011 14.5 0.9 0.93 8.1 0.0 3.7 4 1 0 4 4 4 0 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 CBZ28633.1 - 0.013 15.9 21.6 15 6.2 1.8 8.0 7 2 2 9 9 9 0 HEAT-like repeat CTD PF12815.2 CBZ28633.1 - 0.022 15.1 3.3 0.041 14.2 2.3 1.3 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 NUC173 PF08161.7 CBZ28633.1 - 0.029 13.7 0.2 0.75 9.1 0.0 3.2 3 0 0 3 3 3 0 NUC173 domain DHO_dh PF01180.16 CBZ28633.1 - 0.11 11.4 0.1 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase HEAT PF02985.17 CBZ28633.1 - 0.8 9.9 17.6 6.1 7.1 0.0 7.2 9 0 0 9 9 8 0 HEAT repeat LRR_4 PF12799.2 CBZ28634.1 - 6.5e-11 41.6 2.4 0.00038 20.0 0.0 4.2 2 2 1 4 4 4 3 Leucine Rich repeats (2 copies) IQ PF00612.22 CBZ28634.1 - 7.5e-10 37.5 10.6 1.3e-05 24.3 2.0 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif LRR_8 PF13855.1 CBZ28634.1 - 8.1e-07 28.6 8.1 0.00023 20.8 0.0 3.3 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CBZ28634.1 - 9.8e-05 21.8 6.8 2.3 8.5 0.0 6.0 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.1 CBZ28634.1 - 0.0056 16.6 4.4 6.3 7.1 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 CBZ28634.1 - 0.0086 16.1 6.1 5.2 7.7 0.0 5.4 5 0 0 5 5 5 1 Leucine rich repeat ADP_ribosyl_GH PF03747.9 CBZ28635.1 - 2.1e-11 44.1 1.3 9.5e-08 32.1 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylglycohydrolase IQ PF00612.22 CBZ28636.1 - 5.2e-20 69.1 99.9 0.00013 21.2 1.4 14.3 14 0 0 14 14 14 9 IQ calmodulin-binding motif Fis1_TPR_C PF14853.1 CBZ28636.1 - 0.0099 15.7 0.1 0.025 14.4 0.1 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 CBZ28636.1 - 0.16 11.5 2.8 0.13 11.9 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.15 CBZ28637.1 - 9.4e-71 238.6 10.6 1.2e-70 238.3 7.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CBZ28637.1 - 1.1e-37 129.1 1.2 3e-37 127.7 0.2 2.1 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CBZ28637.1 - 2.7e-08 33.9 4.6 0.25 11.6 0.1 5.1 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 CBZ28637.1 - 3e-06 26.8 4.3 8.2 6.8 0.1 6.5 6 0 0 6 6 6 3 HEAT repeat Cnd1 PF12717.2 CBZ28637.1 - 0.12 12.1 5.6 1.6 8.5 0.1 3.6 1 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CBZ28637.1 - 9.3 6.8 6.7 53 4.4 0.5 3.9 4 0 0 4 4 4 0 HEAT-like repeat MoaC PF01967.16 CBZ28639.1 - 5.8e-20 71.3 0.2 7.4e-19 67.7 0.0 2.6 2 1 0 2 2 2 1 MoaC family His_Phos_2 PF00328.17 CBZ28640.1 - 1.3e-20 74.0 0.0 4e-17 62.5 0.0 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) SelR PF01641.13 CBZ28641.1 - 1.4e-39 134.6 0.0 1.6e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 SelR domain DUF2296 PF10058.4 CBZ28641.1 - 0.0044 16.7 0.3 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) FYVE PF01363.16 CBZ28641.1 - 0.033 14.0 1.1 0.065 13.1 0.7 1.5 1 0 0 1 1 1 0 FYVE zinc finger TF_Zn_Ribbon PF08271.7 CBZ28641.1 - 0.042 13.1 3.3 0.37 10.1 0.1 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding HNH_5 PF14279.1 CBZ28641.1 - 0.043 13.8 0.1 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 HNH endonuclease Yippee-Mis18 PF03226.9 CBZ28641.1 - 0.14 12.1 2.3 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Endonuclease_7 PF02945.10 CBZ28641.1 - 0.23 11.1 2.0 1.1 9.0 1.4 2.1 1 1 0 1 1 1 0 Recombination endonuclease VII Metallophos PF00149.23 CBZ28642.1 - 1.7e-39 135.3 0.2 2.1e-39 135.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase VitD-bind_III PF09164.5 CBZ28642.1 - 0.0035 16.9 0.6 0.0088 15.6 0.4 1.6 1 0 0 1 1 1 1 Vitamin D binding protein, domain III COX15-CtaA PF02628.10 CBZ28643.1 - 6e-86 288.0 14.5 7e-86 287.8 10.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein 2OG-FeII_Oxy_2 PF13532.1 CBZ28646.1 - 3e-05 23.9 0.0 4.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APG12 PF04110.8 CBZ28647.1 - 0.049 13.8 0.0 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DNA_processg_A PF02481.10 CBZ28647.1 - 0.066 12.0 0.1 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 DNA recombination-mediator protein A DUF179 PF02622.10 CBZ28648.1 - 4.8e-05 23.0 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 WD40 PF00400.27 CBZ28649.1 - 4.2e-58 191.2 27.3 4.1e-11 42.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBZ28649.1 - 3e-08 32.2 5.9 0.0044 15.2 0.2 3.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CBZ28649.1 - 8e-08 32.2 0.0 0.0001 22.0 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CBZ28649.1 - 4.4e-05 22.3 0.6 0.34 9.6 0.0 3.6 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 CBZ28649.1 - 0.00096 18.6 0.2 0.089 12.2 0.0 2.1 1 1 1 2 2 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 CBZ28649.1 - 0.029 12.6 0.0 0.79 7.9 0.0 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.7 CBZ28649.1 - 0.035 13.7 0.7 6.4 6.5 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 CBZ28649.1 - 0.16 10.1 0.0 0.51 8.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Spc97_Spc98 PF04130.8 CBZ28650.1 - 7e-58 196.2 0.0 1.1e-57 195.6 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family HSP70 PF00012.15 CBZ28651.1 - 2.5e-271 900.8 5.3 2.9e-271 900.7 3.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ28651.1 - 7.4e-14 51.0 0.0 1.1e-12 47.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CBZ28651.1 - 0.014 15.1 0.4 0.45 10.3 0.3 3.1 1 1 0 1 1 1 0 Cell division protein FtsA FGGY_C PF02782.11 CBZ28651.1 - 0.039 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.15 CBZ28652.1 - 2.6e-107 359.2 0.4 2.9e-107 359.0 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein Terminase_4 PF05119.7 CBZ28652.1 - 0.14 12.3 1.1 8 6.6 0.1 2.4 2 0 0 2 2 2 0 Phage terminase, small subunit bZIP_1 PF00170.16 CBZ28653.1 - 0.81 9.6 7.5 12 5.9 0.7 3.5 3 0 0 3 3 3 0 bZIP transcription factor HALZ PF02183.13 CBZ28653.1 - 5.5 6.7 13.4 1.3 8.7 0.3 3.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Beta-lactamase PF00144.19 CBZ28654.1 - 2.9e-10 39.7 0.1 8.4e-10 38.1 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase HSP70 PF00012.15 CBZ28656.1 - 1.8e-194 647.1 3.8 2.1e-194 646.8 2.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ28656.1 - 5.7e-17 61.3 4.7 1.5e-14 53.3 0.1 2.7 3 0 0 3 3 3 2 MreB/Mbl protein DDR PF08841.5 CBZ28656.1 - 0.0014 17.5 0.8 0.0042 15.9 0.4 1.9 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 CBZ28656.1 - 0.0014 17.9 0.2 0.064 12.5 0.0 2.8 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 CBZ28656.1 - 0.0077 15.3 7.0 0.58 9.2 0.2 3.4 2 1 0 3 3 3 2 Hydantoinase/oxoprolinase DUF3437 PF11919.3 CBZ28656.1 - 0.019 14.6 0.1 0.053 13.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) FtsA PF14450.1 CBZ28656.1 - 0.021 14.6 4.7 0.17 11.7 0.0 4.1 3 2 0 3 3 3 0 Cell division protein FtsA DUF2564 PF10819.3 CBZ28656.1 - 0.048 13.7 0.1 3.8 7.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) ATG16 PF08614.6 CBZ28658.1 - 0.031 14.0 2.7 0.078 12.8 1.8 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) F-box PF00646.28 CBZ28659.1 - 0.066 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain Ldh_1_C PF02866.13 CBZ28660.1 - 1.2e-32 112.9 0.0 1.9e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CBZ28660.1 - 2.7e-32 111.5 0.1 4.5e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Lipase_GDSL_2 PF13472.1 CBZ28660.1 - 0.056 13.5 0.8 1.6 8.8 0.6 2.2 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Phage_Integr_2 PF13009.1 CBZ28661.1 - 0.08 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative phage integrase Dynein_heavy PF03028.10 CBZ28662.1 - 2e-185 617.8 0.0 1.4e-184 615.0 0.0 2.4 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 CBZ28662.1 - 8.2e-96 320.9 0.7 8.2e-96 320.9 0.5 3.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ28662.1 - 1.5e-84 283.1 0.7 5.5e-84 281.3 0.0 2.3 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ28662.1 - 1.5e-72 243.7 0.0 3.5e-72 242.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CBZ28662.1 - 2.3e-43 148.2 0.0 1.4e-42 145.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 CBZ28662.1 - 2.5e-43 147.5 0.1 2.2e-42 144.4 0.1 2.4 1 1 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CBZ28662.1 - 4.8e-42 143.9 10.7 1.1e-41 142.8 7.4 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ28662.1 - 1.4e-24 86.3 0.0 8.4e-07 28.7 0.0 6.1 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ28662.1 - 6.6e-09 36.0 0.5 0.05 13.8 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ28662.1 - 1.8e-07 31.3 0.9 1.9 8.6 0.0 5.6 5 0 0 5 5 5 3 AAA domain AAA_16 PF13191.1 CBZ28662.1 - 4.5e-06 26.7 13.7 0.54 10.2 0.0 7.8 7 1 1 8 8 8 2 AAA ATPase domain AAA_18 PF13238.1 CBZ28662.1 - 2.6e-05 24.5 0.1 0.83 9.9 0.0 5.1 5 0 0 5 5 5 1 AAA domain AAA_14 PF13173.1 CBZ28662.1 - 6.6e-05 22.8 0.0 0.69 9.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CBZ28662.1 - 7.1e-05 23.6 0.0 0.33 11.7 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 CBZ28662.1 - 0.00011 21.8 2.6 0.36 10.6 0.0 4.0 4 0 0 4 4 4 2 Part of AAA domain ResIII PF04851.10 CBZ28662.1 - 0.00021 21.1 0.4 0.36 10.6 0.0 4.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 CBZ28662.1 - 0.0016 18.5 0.0 0.31 11.2 0.0 3.9 3 0 0 3 3 3 1 RNA helicase Dor1 PF04124.7 CBZ28664.1 - 2.2e-23 82.2 6.4 2.9e-23 81.8 4.4 1.1 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 CBZ28664.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec5 ELFV_dehydrog PF00208.16 CBZ28665.1 - 4.9e-87 291.5 4.0 6.5e-87 291.1 2.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CBZ28665.1 - 6.4e-49 164.8 0.0 2.8e-47 159.5 0.0 2.6 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 CBZ28665.1 - 0.00065 19.9 0.2 0.0012 19.0 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 CBZ28665.1 - 0.0066 16.0 0.1 0.018 14.6 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain LdpA_C PF12617.3 CBZ28665.1 - 0.031 13.5 0.0 0.055 12.7 0.0 1.5 1 1 0 1 1 1 0 Iron-Sulfur binding protein C terminal 2-Hacid_dh_C PF02826.14 CBZ28665.1 - 0.033 13.3 0.1 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Na_sulph_symp PF00939.14 CBZ28667.1 - 1.3e-19 70.4 45.0 1.9e-18 66.6 31.2 2.9 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.14 CBZ28667.1 - 3.6e-12 46.6 11.6 5.4e-07 29.6 4.5 3.1 2 1 0 2 2 2 2 SPX domain zf-CCCH PF00642.19 CBZ28669.1 - 0.016 14.8 6.0 0.5 10.1 0.7 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.27 CBZ28670.1 - 0.12 12.3 0.5 0.12 12.3 0.3 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat PQQ_3 PF13570.1 CBZ28670.1 - 1.4 9.2 14.8 9.7 6.6 0.3 5.7 5 1 1 6 6 6 0 PQQ-like domain DUF1631 PF07793.6 CBZ28672.1 - 0.078 11.1 0.1 0.13 10.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DUF1192 PF06698.6 CBZ28674.1 - 0.017 14.8 2.1 0.021 14.6 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF1087 PF06465.8 CBZ28674.1 - 0.23 11.4 6.3 0.058 13.3 1.9 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Pkinase PF00069.20 CBZ28675.1 - 5.8e-49 166.5 0.0 6.9e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28675.1 - 3.1e-27 95.2 0.0 3.8e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28675.1 - 1e-06 27.9 0.0 1.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Cas_Cmr3 PF09700.5 CBZ28675.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr3) Acetyltransf_1 PF00583.19 CBZ28676.1 - 2.6e-13 49.7 0.0 4.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ28676.1 - 7e-09 35.7 0.0 1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CBZ28676.1 - 5.2e-07 29.7 0.0 6.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ28676.1 - 1.2e-06 28.3 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CBZ28676.1 - 0.00085 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 CBZ28676.1 - 0.0037 17.4 0.0 0.0043 17.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBZ28676.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 CBZ28676.1 - 0.073 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mhr1 PF12829.2 CBZ28678.1 - 0.038 13.8 1.3 1.3e+02 2.5 0.0 4.7 5 0 0 5 5 5 0 Transcriptional regulation of mitochondrial recombination Abhydrolase_6 PF12697.2 CBZ28679.1 - 6.1e-17 62.2 0.4 1e-16 61.5 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ28679.1 - 7.6e-07 28.9 0.0 1.7e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ28679.1 - 0.003 17.1 0.1 0.013 15.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pro_isomerase PF00160.16 CBZ28680.1 - 4.4e-18 65.9 0.0 7.2e-18 65.2 0.0 1.3 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UPF0220 PF05255.6 CBZ28682.1 - 9.8e-17 60.6 0.6 2.1e-16 59.6 0.4 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0220) BacA PF02673.13 CBZ28682.1 - 0.0096 15.1 0.1 0.015 14.5 0.0 1.4 1 1 0 1 1 1 1 Bacitracin resistance protein BacA MATH PF00917.21 CBZ28683.1 - 2.2e-06 27.9 0.1 7.5e-06 26.1 0.1 2.0 1 0 0 1 1 1 1 MATH domain CorA PF01544.13 CBZ28683.1 - 2.8 6.8 13.7 3.3 6.6 8.3 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein HTH_AraC PF00165.18 CBZ28684.1 - 0.042 13.6 0.3 0.38 10.6 0.0 2.4 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family Cyclin_N PF00134.18 CBZ28686.1 - 2.7e-24 85.1 0.1 6.2e-24 83.9 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain AAA_25 PF13481.1 CBZ28688.1 - 0.04 13.3 0.0 0.14 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hira PF07569.6 CBZ28688.1 - 0.11 11.7 0.4 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 TUP1-like enhancer of split LRR_4 PF12799.2 CBZ28689.1 - 4.3e-09 35.7 6.1 3.9e-05 23.1 0.4 4.6 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ28689.1 - 1.8e-08 33.9 7.6 0.0016 18.1 0.4 3.9 3 1 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 CBZ28689.1 - 1.9e-05 24.0 5.9 5.8 7.3 0.0 6.6 7 1 1 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.1 CBZ28689.1 - 0.017 15.1 5.7 42 4.6 0.1 5.6 6 0 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 CBZ28689.1 - 0.3 11.4 11.7 9.5 6.9 0.1 5.9 5 1 0 5 5 5 0 Leucine rich repeat FAD-oxidase_C PF02913.14 CBZ28690.1 - 1.9e-47 161.6 0.0 2.8e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CBZ28690.1 - 1.5e-39 134.6 0.0 2.6e-39 133.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CBZ28690.1 - 0.0083 16.0 0.0 0.051 13.4 0.0 2.3 2 0 0 2 2 2 1 Berberine and berberine like SusD-like_2 PF12771.2 CBZ28690.1 - 0.11 10.9 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Starch-binding associating with outer membrane tRNA-synt_2 PF00152.15 CBZ28691.1 - 4.6e-87 291.9 0.0 5.7e-87 291.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CBZ28691.1 - 1.1e-09 37.9 0.1 0.00019 20.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CBZ28691.1 - 1.2e-06 28.2 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CBZ28691.1 - 0.01 15.4 0.0 0.57 9.7 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) FCD PF07729.7 CBZ28691.1 - 0.081 13.2 1.6 0.31 11.3 0.1 2.6 3 0 0 3 3 3 0 FCD domain Yip1 PF04893.12 CBZ28692.1 - 1e-09 38.1 17.6 1.8e-09 37.3 11.9 1.5 1 1 0 1 1 1 1 Yip1 domain Cnd1_N PF12922.2 CBZ28692.1 - 0.11 12.1 0.2 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term LRR_6 PF13516.1 CBZ28693.1 - 1.5e-22 77.0 0.1 2.5e-06 26.9 0.0 5.2 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.2 CBZ28693.1 - 2.1e-10 39.9 0.3 3e-05 23.5 0.0 3.2 1 1 3 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ28693.1 - 1.7e-06 27.2 0.0 0.19 11.8 0.0 5.0 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_8 PF13855.1 CBZ28693.1 - 8.3e-05 22.2 2.2 0.00084 19.0 0.5 2.9 2 2 1 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 CBZ28693.1 - 0.0003 20.5 4.0 0.14 12.4 0.0 4.8 5 0 0 5 5 5 1 Leucine rich repeat Rubis-subs-bind PF09273.6 CBZ28694.1 - 2.5e-10 40.3 0.0 9.1e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding NAD_binding_2 PF03446.10 CBZ28695.1 - 2.2e-52 177.1 0.9 3.9e-52 176.3 0.7 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 CBZ28695.1 - 3.9e-35 120.5 0.6 6.8e-35 119.7 0.4 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 CBZ28695.1 - 4.1e-06 26.0 0.0 4.3e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CBZ28695.1 - 4.8e-05 23.6 0.3 0.00023 21.4 0.0 2.3 3 1 0 3 3 2 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 CBZ28695.1 - 0.00062 19.1 0.1 0.099 12.0 0.0 2.5 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 CBZ28695.1 - 0.00064 19.4 0.2 0.0015 18.2 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CBZ28695.1 - 0.0011 19.1 0.0 0.0021 18.1 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 CBZ28695.1 - 0.0061 15.9 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 CBZ28695.1 - 0.014 15.0 0.6 0.09 12.5 0.0 2.4 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 CBZ28695.1 - 0.074 12.4 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MGAT2 PF05060.9 CBZ28695.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) SAM_1 PF00536.25 CBZ28697.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Gly-zipper_OmpA PF13436.1 CBZ28698.1 - 0.00062 19.4 3.2 0.00085 18.9 2.2 1.1 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 CBZ28698.1 - 0.063 12.9 6.8 0.095 12.3 4.7 1.3 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.10 CBZ28698.1 - 2.9 7.6 9.2 6.2 6.5 6.4 1.5 1 1 0 1 1 1 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 CBZ28698.1 - 3.2 7.9 10.6 5.2 7.2 7.3 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide RrnaAD PF00398.15 CBZ28699.1 - 1.3e-58 198.0 0.0 1.8e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CBZ28699.1 - 2.3e-08 34.0 0.0 5e-08 32.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ28699.1 - 2.9e-05 24.5 0.0 4.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ28699.1 - 8.3e-05 22.2 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ28699.1 - 0.00021 21.7 0.0 0.00038 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ28699.1 - 0.00045 19.9 0.0 0.00074 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ28699.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CBZ28699.1 - 0.0018 18.7 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CBZ28699.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 CBZ28699.1 - 0.025 13.6 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.7 CBZ28699.1 - 0.05 12.4 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_28 PF02636.12 CBZ28699.1 - 0.05 13.0 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.1 CBZ28699.1 - 0.066 13.5 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ28699.1 - 0.067 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family LELP1 PF15042.1 CBZ28699.1 - 0.093 12.9 0.7 4.5 7.4 0.3 2.3 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 zf-RanBP PF00641.13 CBZ28700.1 - 0.00032 19.7 2.3 0.00032 19.7 1.6 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others VHS PF00790.14 CBZ28700.1 - 0.085 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 VHS domain Mito_carr PF00153.22 CBZ28701.1 - 6.4e-13 48.2 0.1 2.6e-08 33.4 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4112 PF13430.1 CBZ28702.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4112) RNase_T PF00929.19 CBZ28703.1 - 3.8e-22 79.3 0.0 7.8e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH_1 PF13423.1 CBZ28703.1 - 8.8e-20 71.3 0.0 1.1e-18 67.6 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2 PF00096.21 CBZ28704.1 - 1e-11 44.4 43.7 0.051 13.9 0.5 8.4 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-Di19 PF05605.7 CBZ28704.1 - 1.4e-11 44.3 31.4 0.0015 18.6 2.8 7.5 7 1 0 7 7 7 4 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CBZ28704.1 - 4.1e-09 36.1 45.2 0.17 12.2 0.2 8.3 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CBZ28704.1 - 1.3e-08 34.6 7.0 0.072 13.2 0.1 5.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CBZ28704.1 - 8.4e-08 32.1 13.2 0.004 17.3 0.4 5.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-met2 PF12907.2 CBZ28704.1 - 8.9e-07 28.7 10.7 0.042 13.8 0.1 5.9 6 0 0 6 6 6 2 Zinc-binding DUF629 PF04780.7 CBZ28704.1 - 0.00025 19.7 4.7 1.8 7.0 0.0 5.2 5 0 0 5 5 5 1 Protein of unknown function (DUF629) zf-H2C2_2 PF13465.1 CBZ28704.1 - 0.00026 21.0 33.1 0.32 11.3 0.1 8.3 9 2 0 9 9 8 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 CBZ28704.1 - 0.0015 18.3 21.7 1.4 8.9 0.0 6.5 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2HC_2 PF13913.1 CBZ28704.1 - 0.12 12.1 20.8 0.08 12.6 0.7 4.7 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 CBZ28704.1 - 0.21 11.9 0.0 0.21 11.9 0.0 6.1 6 1 0 6 6 5 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CBZ28704.1 - 0.66 10.1 21.0 3.3 7.8 0.1 6.3 5 1 0 5 5 5 0 C2H2 type zinc-finger (2 copies) gag_pre-integrs PF13976.1 CBZ28704.1 - 0.9 9.2 4.5 0.69 9.5 0.1 3.0 3 0 0 3 3 3 0 GAG-pre-integrase domain HNH PF01844.18 CBZ28704.1 - 4.6 7.1 10.3 12 5.9 0.0 3.9 3 0 0 3 3 3 0 HNH endonuclease Peptidase_C54 PF03416.14 CBZ28705.1 - 1.5e-38 132.5 0.1 1.2e-37 129.5 0.1 1.9 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 CBZ28705.1 - 0.015 14.3 0.0 0.055 12.5 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C78 LIM PF00412.17 CBZ28706.1 - 4.4e-05 23.4 8.9 4.4e-05 23.4 6.2 2.3 2 1 0 2 2 2 1 LIM domain zf-PARP PF00645.13 CBZ28706.1 - 0.0025 18.0 1.2 0.28 11.4 0.4 2.6 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region NCD3G PF07562.9 CBZ28706.1 - 0.08 12.6 6.3 1.4 8.6 1.3 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR FYVE_2 PF02318.11 CBZ28706.1 - 0.3 11.0 2.6 0.61 10.0 1.8 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Rubis-subs-bind PF09273.6 CBZ28707.1 - 0.058 13.3 0.1 6.5 6.6 0.0 2.6 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding XhlA PF10779.4 CBZ28709.1 - 0.2 11.5 0.1 0.2 11.5 0.0 3.7 5 0 0 5 5 5 0 Haemolysin XhlA Fib_alpha PF08702.5 CBZ28709.1 - 3.8 7.6 15.5 26 4.8 4.8 3.6 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF1043 PF06295.7 CBZ28709.1 - 3.8 7.1 6.8 0.35 10.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) Sad1_UNC PF07738.8 CBZ28710.1 - 1.1e-19 70.5 0.0 1.7e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RabGAP-TBC PF00566.13 CBZ28711.1 - 8.7e-08 31.8 0.6 1.4e-07 31.2 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 CBZ28711.1 - 0.0047 17.2 0.0 0.013 15.7 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain Ku PF02735.11 CBZ28712.1 - 2.2e-16 59.8 0.0 6.1e-16 58.4 0.0 1.7 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 CBZ28712.1 - 1.1e-13 51.1 0.0 2.4e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 CBZ28712.1 - 2.2e-11 43.6 0.0 5.8e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 CBZ28712.1 - 0.054 14.0 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Kinesin PF00225.18 CBZ28713.1 - 2e-89 299.6 0.1 3e-89 299.0 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF904 PF06005.7 CBZ28713.1 - 0.0012 19.0 2.1 0.48 10.7 1.5 3.0 1 1 0 1 1 1 1 Protein of unknown function (DUF904) AAA_22 PF13401.1 CBZ28713.1 - 0.025 14.7 0.1 0.39 10.8 0.0 2.8 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 CBZ28713.1 - 0.051 13.5 0.3 0.2 11.6 0.0 2.1 2 1 1 3 3 3 0 AAA ATPase domain DivIC PF04977.10 CBZ28713.1 - 0.06 12.8 10.5 0.26 10.7 0.3 3.4 3 0 0 3 3 3 0 Septum formation initiator Cadherin_2 PF08266.7 CBZ28713.1 - 0.065 12.8 0.6 0.18 11.4 0.4 1.7 1 0 0 1 1 1 0 Cadherin-like HAP1_N PF04849.8 CBZ28713.1 - 0.29 10.0 19.9 0.019 13.8 3.4 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region PIF1 PF05970.9 CBZ28713.1 - 0.39 9.6 4.6 0.075 11.9 0.2 1.8 2 0 0 2 2 2 0 PIF1-like helicase CDC37_N PF03234.9 CBZ28713.1 - 0.97 9.7 8.7 1.8 8.8 1.6 2.6 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding bZIP_1 PF00170.16 CBZ28713.1 - 1.8 8.5 15.5 0.055 13.4 1.2 3.6 2 1 1 3 3 3 0 bZIP transcription factor EMP70 PF02990.11 CBZ28714.1 - 1.5e-135 452.6 7.6 2.2e-135 452.0 5.3 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Pkinase PF00069.20 CBZ28715.1 - 1.6e-59 201.1 0.0 2.3e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28715.1 - 1e-26 93.5 0.0 1.4e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28715.1 - 1.1e-05 24.5 0.0 0.00031 19.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CBZ28715.1 - 0.16 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PP2C PF00481.16 CBZ28716.1 - 6.7e-50 169.8 0.1 8.9e-50 169.4 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ28716.1 - 2.8e-05 23.6 0.1 0.00016 21.1 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CBZ28716.1 - 8.8e-05 22.2 0.0 0.0003 20.5 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Shisa PF13908.1 CBZ28717.1 - 0.0028 17.8 0.0 0.0042 17.2 0.0 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Abhydrolase_5 PF12695.2 CBZ28718.1 - 2.8e-14 53.0 0.0 6e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ28718.1 - 1.4e-12 47.9 0.3 3.3e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 CBZ28718.1 - 4.6e-08 32.8 0.0 2.6e-07 30.3 0.0 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 CBZ28718.1 - 3.4e-05 23.5 3.4 0.037 13.5 0.1 2.8 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBZ28718.1 - 0.00059 19.1 0.0 0.011 14.9 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 CBZ28718.1 - 0.005 16.6 0.0 0.009 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 CBZ28718.1 - 0.011 14.2 0.0 0.8 8.1 0.0 2.2 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 CBZ28718.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PhoPQ_related PF10142.4 CBZ28718.1 - 0.069 11.6 0.0 0.1 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein BAAT_C PF08840.6 CBZ28718.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAP2 PF01569.16 CBZ28719.1 - 1.3e-21 76.6 4.4 2.4e-21 75.7 3.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily Scs3p PF10261.4 CBZ28719.1 - 0.021 13.8 0.7 0.042 12.8 0.0 1.8 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM WD40 PF00400.27 CBZ28720.1 - 9.4e-44 145.7 12.3 1.4e-12 46.9 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CBZ28720.1 - 1.5e-06 28.0 0.0 0.17 11.6 0.0 3.1 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CBZ28720.1 - 0.14 11.6 0.0 10 5.6 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DAGK_cat PF00781.19 CBZ28721.1 - 7.1e-12 44.8 0.1 1.3e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Evr1_Alr PF04777.8 CBZ28722.1 - 1.3e-10 41.0 0.0 5.5e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.15 CBZ28722.1 - 2.1e-07 30.5 0.0 4.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin BIV_Env PF05858.7 CBZ28722.1 - 0.13 10.1 0.0 0.2 9.5 0.0 1.2 1 0 0 1 1 1 0 Bovine immunodeficiency virus surface protein (SU) RRF PF01765.14 CBZ28723.1 - 3.8e-14 52.4 1.6 4.5e-14 52.2 0.5 1.5 1 1 0 1 1 1 1 Ribosome recycling factor Activator-TraM PF11657.3 CBZ28723.1 - 0.09 12.2 4.3 0.095 12.1 0.4 2.1 2 0 0 2 2 2 0 Transcriptional activator TraM PA28_alpha PF02251.13 CBZ28723.1 - 0.15 12.2 0.2 0.89 9.7 0.0 2.3 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit IF4E PF01652.13 CBZ28724.1 - 1.2e-31 109.4 0.0 1.7e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PAM2 PF07145.10 CBZ28724.1 - 0.82 9.3 0.1 0.82 9.3 0.0 2.6 3 0 0 3 3 3 0 Ataxin-2 C-terminal region tRNA-synt_2 PF00152.15 CBZ28725.1 - 9.6e-73 244.8 0.0 1.4e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CBZ28725.1 - 1.5e-09 37.5 0.1 2.7e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CBZ28725.1 - 0.00014 21.1 0.3 0.13 11.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Bystin PF05291.6 CBZ28727.1 - 2.9e-109 364.6 0.1 4.4e-109 364.0 0.1 1.1 1 0 0 1 1 1 1 Bystin Nucleoplasmin PF03066.10 CBZ28730.1 - 0.88 9.0 8.6 1.4 8.4 6.0 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 CBZ28730.1 - 0.92 9.8 3.9 4.5 7.6 2.7 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 CBZ28730.1 - 1.9 7.7 4.1 3.2 6.9 2.8 1.3 1 0 0 1 1 1 0 NOA36 protein PAT1 PF09770.4 CBZ28730.1 - 1.9 6.6 22.0 0.35 9.0 2.1 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 TMEM171 PF15471.1 CBZ28730.1 - 3.6 6.3 10.9 8.1 5.1 7.5 1.6 1 0 0 1 1 1 0 Transmembrane protein family 171 Apt1 PF10351.4 CBZ28730.1 - 6.5 5.4 7.9 13 4.5 5.5 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain LRR_4 PF12799.2 CBZ28731.1 - 8.4e-09 34.8 0.1 3e-05 23.5 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ28731.1 - 0.00014 21.5 0.0 0.00055 19.6 0.0 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.1 CBZ28731.1 - 0.025 14.6 0.1 2.9 8.2 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.28 CBZ28731.1 - 0.073 13.1 0.6 24 5.4 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat NatB_MDM20 PF09797.4 CBZ28732.1 - 2.2e-74 250.3 0.0 5.5e-74 249.0 0.0 1.6 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 CBZ28732.1 - 0.035 14.7 1.5 0.035 14.7 1.0 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ28732.1 - 0.044 14.4 0.8 0.044 14.4 0.6 4.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ28732.1 - 0.056 13.0 2.6 0.22 11.1 0.7 2.7 2 0 0 2 2 2 0 TPR repeat Alg14 PF08660.6 CBZ28733.1 - 5e-55 186.0 0.0 7.7e-55 185.4 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.11 CBZ28733.1 - 1.5e-19 70.2 0.0 6.5e-19 68.1 0.0 2.0 2 1 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CBZ28733.1 - 0.024 13.8 0.2 0.068 12.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 1 RRM_1 PF00076.17 CBZ28734.1 - 6.1e-16 57.8 0.0 9.2e-16 57.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ28734.1 - 6.1e-13 48.5 0.0 9.7e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ28734.1 - 1.1e-08 34.7 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phospho_p8 PF10195.4 CBZ28734.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 DNA-binding nuclear phosphoprotein p8 LMBR1 PF04791.11 CBZ28735.1 - 3.1e-26 92.0 26.0 1e-25 90.2 18.0 1.7 1 1 0 1 1 1 1 LMBR1-like membrane protein Wzz PF02706.10 CBZ28735.1 - 8.4 6.2 7.2 0.67 9.7 0.2 2.3 2 0 0 2 2 2 0 Chain length determinant protein PSP PF04046.11 CBZ28737.1 - 2.3e-20 71.6 3.2 6e-20 70.3 2.2 1.8 1 0 0 1 1 1 1 PSP DUF382 PF04037.8 CBZ28737.1 - 4.1e-12 46.0 0.1 9.4e-11 41.6 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF382) LUC7 PF03194.10 CBZ28737.1 - 1 8.8 5.3 1.4 8.4 3.7 1.2 1 0 0 1 1 1 0 LUC7 N_terminus AMP-binding PF00501.23 CBZ28738.1 - 1.7e-26 92.5 0.0 2.8e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme BBS2_C PF14782.1 CBZ28739.1 - 1.2e-132 442.6 0.0 1.6e-132 442.1 0.0 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.1 CBZ28739.1 - 1.9e-28 98.4 0.0 1.3e-27 95.8 0.0 2.4 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.1 CBZ28739.1 - 4.1e-10 39.4 0.1 1.2e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal FG-GAP PF01839.18 CBZ28739.1 - 5.7e-05 22.6 0.1 0.00017 21.2 0.1 1.7 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.1 CBZ28739.1 - 0.00083 19.6 1.5 0.044 14.1 0.2 1.7 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FlgN PF05130.7 CBZ28739.1 - 0.0044 17.2 2.3 0.0044 17.2 1.6 2.3 2 1 0 2 2 2 1 FlgN protein HALZ PF02183.13 CBZ28739.1 - 9.9 5.9 8.7 0.47 10.2 1.9 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Pkinase PF00069.20 CBZ28740.1 - 4.1e-65 219.5 0.0 5.4e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28740.1 - 1.9e-41 141.8 0.0 2.8e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28740.1 - 0.00072 18.5 0.0 0.003 16.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Cyt-b5 PF00173.23 CBZ28741.1 - 7.2e-27 93.0 0.0 3e-17 62.1 0.0 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 CBZ28741.1 - 1.7e-11 44.6 0.0 4e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBZ28741.1 - 1.7e-07 31.2 0.0 4.4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CBZ28741.1 - 4e-06 26.8 0.0 0.00076 19.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain PuR_N PF09182.5 CBZ28741.1 - 0.15 11.6 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal RRS1 PF04939.7 CBZ28742.1 - 6.8e-48 162.2 5.1 6.8e-48 162.2 3.5 1.4 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) DUF106 PF01956.11 CBZ28742.1 - 2.5 7.6 5.3 6.2 6.3 3.6 1.6 1 1 0 1 1 1 0 Integral membrane protein DUF106 FliD_N PF02465.13 CBZ28742.1 - 4.6 7.6 7.6 2.1 8.7 3.6 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus tRNA-synt_His PF13393.1 CBZ28743.1 - 1.6e-38 132.5 0.0 2.3e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CBZ28743.1 - 1.5e-15 57.2 0.0 2.4e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBZ28743.1 - 1.7e-06 27.8 0.1 7.4e-06 25.8 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain PPR_3 PF13812.1 CBZ28745.1 - 0.067 13.4 0.0 0.34 11.3 0.0 2.2 2 0 0 2 2 2 0 Pentatricopeptide repeat domain PDZ_2 PF13180.1 CBZ28746.1 - 1.6e-11 43.9 0.1 4.6e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 CBZ28746.1 - 1.1e-06 28.6 0.0 2.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PI-PLC-X PF00388.14 CBZ28746.1 - 1.3e-05 24.6 0.0 2.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.6 CBZ28746.1 - 6.2e-05 22.9 0.0 0.00022 21.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PI-PLC-Y PF00387.14 CBZ28746.1 - 0.14 12.1 0.0 0.44 10.5 0.0 1.8 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain Ribosomal_S30 PF04758.9 CBZ28747.1 - 5e-28 96.6 6.7 5.7e-28 96.4 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.9 CBZ28748.1 - 5e-28 96.6 6.7 5.7e-28 96.4 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 CS PF04969.11 CBZ28749.1 - 9.3e-16 58.1 0.0 1.6e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 CBZ28751.1 - 4e-26 90.4 18.5 7.8e-11 41.4 0.9 5.9 5 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 CBZ28751.1 - 5.7e-25 85.1 21.8 0.00047 19.8 0.3 8.9 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ28751.1 - 4.9e-24 82.8 15.8 3.3e-05 23.3 0.2 7.7 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ28751.1 - 7e-18 64.3 15.0 4e-08 33.0 0.4 5.4 4 1 1 5 5 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ28751.1 - 1.3e-17 63.9 8.6 0.0021 18.6 0.0 6.2 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ28751.1 - 1.3e-16 60.6 1.0 0.00026 21.2 0.1 6.3 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ28751.1 - 1.4e-16 58.9 7.6 0.00027 20.5 0.1 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ28751.1 - 1.6e-13 49.3 13.5 0.0029 17.2 0.3 6.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ28751.1 - 2.5e-11 43.1 8.7 0.79 10.5 0.0 8.0 8 1 2 10 10 8 4 Tetratricopeptide repeat Apc3 PF12895.2 CBZ28751.1 - 6.2e-09 35.8 24.4 0.0021 18.1 1.4 4.5 4 2 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CBZ28751.1 - 4.2e-08 32.5 0.7 0.00072 18.7 0.0 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ28751.1 - 2e-07 31.0 13.5 0.0026 18.1 0.5 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ28751.1 - 0.00082 19.1 4.3 0.4 10.5 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.1 CBZ28751.1 - 0.0018 17.4 3.0 0.0018 17.4 2.1 2.9 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP BTAD PF03704.12 CBZ28751.1 - 0.0093 16.2 8.9 0.26 11.5 0.1 4.6 4 2 1 5 5 4 1 Bacterial transcriptional activator domain TPR_10 PF13374.1 CBZ28751.1 - 0.014 15.2 13.6 0.061 13.2 0.2 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat NARP1 PF12569.3 CBZ28751.1 - 0.069 11.9 0.3 0.15 10.8 0.1 1.7 2 1 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_17 PF13431.1 CBZ28751.1 - 0.074 13.2 13.1 15 6.0 0.0 7.3 10 1 1 11 11 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ28751.1 - 0.14 12.0 16.7 2.6 7.9 0.1 6.2 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 CBZ28751.1 - 0.27 11.0 2.9 0.36 10.6 0.2 2.5 3 0 0 3 3 2 0 Domain of Unknown Function (DUF3856) Sel1 PF08238.7 CBZ28751.1 - 0.3 11.7 16.4 8.6 7.1 0.0 6.0 7 0 0 7 7 6 0 Sel1 repeat TPR_3 PF07720.7 CBZ28751.1 - 4.2 7.2 10.3 5.3 6.9 0.0 5.1 7 0 0 7 7 5 0 Tetratricopeptide repeat GrpE PF01025.14 CBZ28753.1 - 6.9e-41 139.5 2.7 8.7e-41 139.2 1.9 1.1 1 0 0 1 1 1 1 GrpE DUF416 PF04222.7 CBZ28753.1 - 0.074 12.1 0.5 0.16 11.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF416) GrpE PF01025.14 CBZ28754.1 - 1e-32 112.9 0.6 1.3e-32 112.6 0.4 1.1 1 0 0 1 1 1 1 GrpE Atg14 PF10186.4 CBZ28754.1 - 0.23 10.3 5.7 0.33 9.8 4.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Peptidase_S64 PF08192.6 CBZ28756.1 - 0.0084 14.4 0.1 0.011 14.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase family S64 DJ-1_PfpI PF01965.19 CBZ28757.1 - 1e-23 83.4 0.1 1.2e-23 83.1 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 CBZ28757.1 - 2.4e-13 49.6 0.1 3e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase Arm PF00514.18 CBZ28758.1 - 1.7e-21 75.1 19.7 0.021 14.6 0.0 11.7 13 0 0 13 13 13 6 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 CBZ28758.1 - 5.8e-13 48.4 12.3 0.12 12.1 0.0 8.0 5 3 2 8 8 8 6 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.1 CBZ28758.1 - 5.9e-10 39.3 11.2 0.0045 17.2 0.2 6.2 4 1 1 6 6 6 3 HEAT repeats HEAT_EZ PF13513.1 CBZ28758.1 - 1.2e-05 25.6 9.7 0.28 11.7 0.2 5.8 5 2 0 5 5 5 2 HEAT-like repeat DOG1 PF14144.1 CBZ28758.1 - 0.025 14.6 2.9 3.6 7.6 0.0 4.1 5 0 0 5 5 5 0 Seed dormancy control HEAT PF02985.17 CBZ28758.1 - 0.054 13.5 7.1 30 5.0 0.0 6.4 6 0 0 6 6 6 0 HEAT repeat Pkinase PF00069.20 CBZ28762.1 - 3.3e-70 236.2 0.0 4.7e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28762.1 - 4.6e-32 111.0 0.0 7.9e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CBZ28762.1 - 0.00011 22.3 0.1 0.00023 21.3 0.1 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CBZ28762.1 - 0.00025 20.1 0.0 0.0006 18.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBZ28762.1 - 0.0084 15.1 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ28762.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PH_9 PF15410.1 CBZ28762.1 - 0.046 13.8 0.7 25 5.0 0.1 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain FeoB_C PF07664.7 CBZ28763.1 - 0.028 13.8 1.8 0.11 11.8 1.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B C terminus UPF0233 PF06781.7 CBZ28764.1 - 0.07 12.7 0.1 0.16 11.5 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF3481 PF11980.3 CBZ28764.1 - 0.65 9.8 2.0 1.8 8.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3481) Methyltransf_PK PF05891.7 CBZ28765.1 - 6.7e-65 218.4 0.0 8.2e-65 218.1 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_11 PF08241.7 CBZ28765.1 - 3.7e-11 43.3 0.0 5.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ28765.1 - 1.7e-06 28.3 0.0 2.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ28765.1 - 2.9e-06 26.9 0.0 4.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ28765.1 - 1e-05 26.0 0.0 1.6e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ28765.1 - 1.6e-05 25.2 0.0 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ28765.1 - 2.3e-05 24.1 0.0 3.6e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CBZ28765.1 - 6.7e-05 22.3 0.0 0.00011 21.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 CBZ28765.1 - 0.00013 21.2 0.0 0.00014 21.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 CBZ28765.1 - 0.0084 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF4105 PF13387.1 CBZ28765.1 - 0.033 13.3 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Prefoldin_2 PF01920.15 CBZ28767.1 - 3.2e-07 30.0 1.9 3.2e-07 30.0 1.3 1.7 1 1 0 1 1 1 1 Prefoldin subunit Med30 PF11315.3 CBZ28767.1 - 0.42 10.7 5.1 1.4 9.0 3.5 1.8 1 1 0 1 1 1 0 Mediator complex subunit 30 YgaB PF14182.1 CBZ28767.1 - 0.63 10.3 6.0 3.2 8.0 0.7 2.3 2 0 0 2 2 2 0 YgaB-like protein OmpH PF03938.9 CBZ28767.1 - 3.8 7.4 10.1 9.1 6.1 7.0 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) MMR_HSR1 PF01926.18 CBZ28768.1 - 6.7e-08 32.4 0.0 9.7e-07 28.7 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CBZ28768.1 - 1.8e-05 24.4 0.0 0.00025 20.6 0.0 2.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CBZ28768.1 - 0.00017 21.1 0.0 0.00034 20.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBZ28768.1 - 0.00045 19.5 0.1 0.23 10.7 0.0 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B Dynamin_N PF00350.18 CBZ28768.1 - 0.0012 18.6 0.0 0.034 13.9 0.0 2.7 2 1 0 2 2 2 1 Dynamin family DUF258 PF03193.11 CBZ28768.1 - 0.042 13.0 0.0 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Amastin PF07344.6 CBZ28769.1 - 2.2e-42 144.2 8.4 2.7e-42 144.0 5.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2628 PF10947.3 CBZ28769.1 - 0.98 9.2 5.1 1.9 8.3 3.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Amastin PF07344.6 CBZ28770.1 - 2.9e-42 143.9 8.2 3.5e-42 143.6 5.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2628 PF10947.3 CBZ28770.1 - 1.1 9.0 5.6 2.6 7.8 3.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Amastin PF07344.6 CBZ28771.1 - 3.1e-40 137.3 5.3 4e-40 136.9 3.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Yip1 PF04893.12 CBZ28771.1 - 0.0083 15.6 5.4 0.0083 15.6 3.7 2.0 2 0 0 2 2 2 1 Yip1 domain DUF914 PF06027.7 CBZ28771.1 - 0.011 14.6 0.2 0.017 13.9 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) DUF3681 PF12442.3 CBZ28771.1 - 0.017 15.2 0.3 0.067 13.3 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3681) Claudin_2 PF13903.1 CBZ28771.1 - 0.28 10.8 14.4 2.5 7.7 10.2 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction zf-LITAF-like PF10601.4 CBZ28771.1 - 0.6 10.0 2.8 4.5 7.2 0.0 2.9 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Pox_A14 PF05767.7 CBZ28771.1 - 0.84 9.6 6.6 6.1 6.8 0.3 3.1 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Flavi_NS4A PF01350.12 CBZ28771.1 - 1.1 8.8 3.5 11 5.5 0.0 2.5 3 0 0 3 3 3 0 Flavivirus non-structural protein NS4A PfkB PF00294.19 CBZ28772.1 - 4.1e-57 193.6 0.3 4.9e-57 193.3 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DAGK_cat PF00781.19 CBZ28772.1 - 0.08 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PfkB PF00294.19 CBZ28773.1 - 3.3e-27 95.4 0.2 4.5e-27 94.9 0.2 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HECT PF00632.20 CBZ28775.1 - 4e-76 256.1 0.0 6.2e-76 255.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4139 PF13598.1 CBZ28777.1 - 6.2e-94 314.8 0.1 9.1e-94 314.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 CBZ28777.1 - 1.3e-06 28.8 1.9 7.4e-05 23.1 0.4 2.6 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Cob_adeno_trans PF01923.13 CBZ28777.1 - 0.0062 16.3 0.3 16 5.2 0.0 3.2 3 0 0 3 3 3 2 Cobalamin adenosyltransferase TPIP1 PF15338.1 CBZ28777.1 - 0.06 13.2 0.8 2.9 7.7 0.1 2.4 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 Matrilin_ccoil PF10393.4 CBZ28777.1 - 0.84 9.0 9.8 0.72 9.2 0.3 2.8 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Spc97_Spc98 PF04130.8 CBZ28778.1 - 5.3e-23 81.1 0.0 3.3e-22 78.5 0.0 2.0 1 1 0 1 1 1 1 Spc97 / Spc98 family RWP-RK PF02042.10 CBZ28778.1 - 0.069 12.9 0.1 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 RWP-RK domain DUF4214 PF13946.1 CBZ28778.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) WD40 PF00400.27 CBZ28779.1 - 7.5e-23 79.5 11.4 1.2e-09 37.6 0.4 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CBZ28779.1 - 6.5e-13 48.3 0.0 1.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex PAX PF00292.13 CBZ28780.1 - 0.034 13.8 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain MAM33 PF02330.11 CBZ28781.1 - 1.5e-18 67.3 2.1 9.4e-18 64.7 1.9 1.7 1 1 1 2 2 2 1 Mitochondrial glycoprotein ABM PF03992.11 CBZ28781.1 - 0.064 13.2 0.2 0.41 10.7 0.0 2.4 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase Casein PF00363.13 CBZ28782.1 - 0.026 15.1 0.5 0.056 14.0 0.3 1.5 1 0 0 1 1 1 0 Casein FGase PF05013.7 CBZ28782.1 - 0.04 13.7 1.0 0.088 12.6 0.2 1.8 2 0 0 2 2 2 0 N-formylglutamate amidohydrolase Pkinase PF00069.20 CBZ28784.1 - 6.2e-36 123.8 0.0 5.9e-14 51.8 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28784.1 - 7.1e-22 77.7 0.0 3.5e-13 49.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28784.1 - 0.043 12.7 0.0 0.27 10.1 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Ufd2P_core PF10408.4 CBZ28785.1 - 5.1e-126 421.4 0.0 6.6e-126 421.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core Thioredoxin PF00085.15 CBZ28785.1 - 2.7e-22 78.4 0.0 5.6e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBZ28785.1 - 7.3e-05 22.8 0.1 0.011 15.8 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBZ28785.1 - 0.00016 21.8 0.9 0.00035 20.7 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CBZ28785.1 - 0.00043 20.2 0.1 0.0014 18.6 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like U-box PF04564.10 CBZ28785.1 - 0.0021 18.0 0.0 0.018 14.9 0.0 2.7 2 0 0 2 2 2 1 U-box domain Thioredoxin_9 PF14595.1 CBZ28785.1 - 0.0049 16.4 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CBZ28785.1 - 0.026 14.1 0.1 0.094 12.3 0.0 1.9 1 1 1 2 2 2 0 AhpC/TSA family DnaJ PF00226.26 CBZ28787.1 - 2.6e-20 71.9 0.3 4.5e-20 71.1 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.22 CBZ28789.1 - 8.3e-49 163.2 2.9 1.4e-16 59.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RF-1 PF00472.15 CBZ28790.1 - 1.4e-16 60.2 0.0 2.5e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 RF-1 domain TRF PF08558.5 CBZ28790.1 - 0.026 13.8 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) MRP-S28 PF10213.4 CBZ28790.1 - 0.077 13.0 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Sdh5 PF03937.11 CBZ28791.1 - 1.4e-19 69.5 1.1 2.6e-19 68.6 0.8 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase IQ PF00612.22 CBZ28792.1 - 5.8e-08 31.6 20.9 0.0049 16.4 0.4 5.8 5 0 0 5 5 5 5 IQ calmodulin-binding motif WW PF00397.21 CBZ28793.1 - 2.1e-10 40.2 2.4 3.9e-10 39.4 1.7 1.5 1 0 0 1 1 1 1 WW domain ATG16 PF08614.6 CBZ28793.1 - 0.023 14.5 0.5 0.023 14.5 0.4 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) LTV PF04180.9 CBZ28793.1 - 0.095 12.1 1.6 0.15 11.4 1.1 1.2 1 0 0 1 1 1 0 Low temperature viability protein Golgin_A5 PF09787.4 CBZ28793.1 - 4.8 5.6 6.9 9.3 4.6 4.8 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DREV PF05219.7 CBZ28794.1 - 9.9e-64 214.7 0.0 1.2e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.1 CBZ28794.1 - 6.9e-14 51.8 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ28794.1 - 3.1e-12 46.8 0.0 5.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ28794.1 - 3.1e-11 43.6 0.0 5.3e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ28794.1 - 1.4e-07 32.0 0.0 2.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ28794.1 - 1.9e-06 27.5 0.0 6.1e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ28794.1 - 0.0024 18.2 0.0 0.0081 16.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 CBZ28794.1 - 0.0026 16.8 0.0 0.0035 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CheR PF01739.13 CBZ28794.1 - 0.0071 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 CBZ28794.1 - 0.01 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 CBZ28794.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) RRM_1 PF00076.17 CBZ28795.1 - 3.4e-23 81.0 0.0 1.6e-09 37.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ28795.1 - 2.7e-15 56.0 0.0 1.6e-05 24.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ28795.1 - 3.2e-11 42.8 0.0 0.0038 17.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CBZ28795.1 - 0.015 15.2 0.0 0.61 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain Nup35_RRM_2 PF14605.1 CBZ28795.1 - 0.021 14.5 0.1 6.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Arm PF00514.18 CBZ28796.1 - 1e-67 221.8 20.6 4.7e-10 38.9 0.0 9.1 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CBZ28796.1 - 9.6e-20 70.6 1.8 0.00013 22.1 0.0 5.4 1 1 5 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 CBZ28796.1 - 5.2e-17 61.7 9.4 0.00049 20.4 0.1 6.4 6 2 2 8 8 8 4 HEAT-like repeat HEAT PF02985.17 CBZ28796.1 - 1.2e-12 46.7 11.7 0.051 13.6 0.0 8.0 9 0 0 9 9 9 5 HEAT repeat Arm_2 PF04826.8 CBZ28796.1 - 0.00013 21.1 0.0 0.021 13.9 0.0 3.5 3 1 1 4 4 4 1 Armadillo-like V-ATPase_H_C PF11698.3 CBZ28796.1 - 0.00052 19.9 0.0 54 3.7 0.0 4.8 3 2 0 4 4 4 0 V-ATPase subunit H Proteasom_PSMB PF10508.4 CBZ28796.1 - 0.0021 16.4 0.0 0.0034 15.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 CBZ28796.1 - 0.079 11.2 0.0 0.59 8.3 0.0 2.3 1 1 1 2 2 2 0 Adaptin N terminal region PgaD PF13994.1 CBZ28797.1 - 0.062 12.7 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 PgaD-like protein MA3 PF02847.12 CBZ28799.1 - 5.5e-07 29.2 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 CBZ28799.1 - 0.049 13.0 0.0 0.27 10.6 0.0 2.2 1 1 0 1 1 1 0 MIF4G domain CAF-1_p150 PF11600.3 CBZ28799.1 - 6.2 6.1 31.2 3 7.1 15.7 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-DHHC PF01529.15 CBZ28801.1 - 1.1e-42 145.4 0.8 1.7e-42 144.7 0.5 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase TMEM107 PF14995.1 CBZ28802.1 - 1.1e-35 122.4 6.0 1.4e-35 122.1 4.2 1.1 1 0 0 1 1 1 1 Transmembrane protein Cupin_8 PF13621.1 CBZ28803.1 - 3e-19 69.5 0.0 8e-19 68.1 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CBZ28803.1 - 2.6e-10 40.5 0.2 3.8e-07 30.3 0.1 2.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase Cupin_2 PF07883.6 CBZ28803.1 - 0.00046 19.6 0.3 0.01 15.3 0.1 2.4 2 0 0 2 2 2 1 Cupin domain F-box-like PF12937.2 CBZ28803.1 - 0.016 14.9 1.9 0.016 14.9 1.3 2.3 2 0 0 2 2 2 0 F-box-like Cupin_4 PF08007.7 CBZ28803.1 - 0.023 13.9 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein UCH PF00443.24 CBZ28804.1 - 3.6e-41 141.0 0.0 5.8e-41 140.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ28804.1 - 4.1e-05 23.1 4.4 0.066 12.6 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase LSM PF01423.17 CBZ28805.1 - 3.3e-14 52.1 0.1 3.8e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain AAA_28 PF13521.1 CBZ28806.1 - 2.5e-18 66.5 0.0 4.3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CBZ28806.1 - 0.0096 14.7 0.1 0.016 14.0 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 CBZ28806.1 - 0.013 16.2 0.0 0.028 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBZ28806.1 - 0.054 13.0 0.1 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DAP3 PF10236.4 CBZ28806.1 - 0.09 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 zf-C3HC4_3 PF13920.1 CBZ28807.1 - 2.3e-08 33.5 13.0 2.3e-08 33.5 9.0 3.6 2 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ28807.1 - 0.00015 21.5 15.3 0.00015 21.5 10.6 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ28807.1 - 0.00027 20.9 16.1 0.00027 20.9 11.2 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF1675 PF07897.6 CBZ28807.1 - 0.037 13.8 5.1 0.093 12.5 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Rtf2 PF04641.7 CBZ28807.1 - 3.1 6.9 7.0 7 5.7 1.4 2.6 2 0 0 2 2 2 0 Rtf2 RING-finger EF-hand_7 PF13499.1 CBZ28808.1 - 0.00084 19.4 0.2 0.0029 17.7 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ28808.1 - 0.021 14.6 0.0 0.067 13.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.27 CBZ28808.1 - 0.053 12.8 0.2 0.21 11.0 0.0 2.1 3 0 0 3 3 3 0 EF hand EF-hand_5 PF13202.1 CBZ28808.1 - 0.067 12.5 0.1 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 EF hand Phos_pyr_kin PF08543.7 CBZ28809.1 - 4.5e-17 62.0 0.0 5.8e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CBZ28809.1 - 6.6e-13 48.4 1.8 2.1e-10 40.2 0.4 2.6 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Acetyltransf_1 PF00583.19 CBZ28810.1 - 3.4e-05 23.7 0.1 0.00023 21.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CBZ28810.1 - 0.00021 21.3 0.0 0.002 18.2 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CBZ28810.1 - 0.00031 20.5 0.0 0.0046 16.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CBZ28810.1 - 0.00055 19.6 0.1 0.026 14.2 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein CENP-F_leu_zip PF10473.4 CBZ28812.1 - 0.00015 21.6 0.9 0.00015 21.6 0.6 3.8 4 1 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 CBZ28812.1 - 0.0079 15.9 0.4 0.0079 15.9 0.3 5.2 4 2 1 5 5 5 1 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 CBZ28812.1 - 0.0083 15.3 7.5 0.4 9.7 0.4 2.6 1 1 0 2 2 2 2 Reovirus sigma C capsid protein Seryl_tRNA_N PF02403.17 CBZ28812.1 - 0.028 14.4 1.1 0.028 14.4 0.8 4.4 4 1 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 CBZ28812.1 - 0.3 11.1 8.5 6.7 6.8 0.1 3.7 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.1 CBZ28812.1 - 2.3 8.5 10.4 11 6.2 7.2 2.2 1 1 0 1 1 1 0 AAA domain DUF802 PF05650.6 CBZ28812.1 - 3 8.0 23.3 1.2 9.3 4.5 4.3 2 1 0 2 2 2 0 Domain of unknown function (DUF802) NPV_P10 PF05531.7 CBZ28812.1 - 4.5 7.6 12.6 27 5.1 0.4 4.7 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 CBZ28812.1 - 6.4 5.0 8.7 1.3 7.4 3.3 1.8 2 0 0 2 2 2 0 AAA domain Clathrin PF00637.15 CBZ28813.1 - 4.6e-09 36.0 0.1 6.1e-07 29.1 0.3 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 CBZ28813.1 - 1.5e-05 24.7 1.6 6.7e-05 22.6 1.1 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ28813.1 - 0.00032 20.6 1.1 0.0011 18.9 0.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CBZ28813.1 - 0.0056 16.3 0.5 0.016 14.8 0.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CBZ28813.1 - 0.028 14.2 0.1 0.075 12.8 0.1 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 CBZ28813.1 - 0.073 13.1 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 CBZ28813.1 - 0.34 10.6 4.1 0.098 12.4 0.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.6 CBZ28813.1 - 1.6 8.8 6.4 0.12 12.4 0.5 2.2 2 0 0 2 2 2 0 RING-like domain Brix PF04427.13 CBZ28814.1 - 5.1e-45 153.4 0.4 6.6e-45 153.1 0.2 1.1 1 0 0 1 1 1 1 Brix domain SNF2_N PF00176.18 CBZ28815.1 - 4.2e-48 163.6 0.0 6e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ28815.1 - 7.4e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ28815.1 - 0.013 15.3 0.0 0.9 9.3 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 CBZ28817.1 - 1.9e-19 70.3 0.3 1.7e-12 47.8 0.3 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CBZ28817.1 - 1.6e-09 38.1 0.1 0.00012 22.1 0.0 2.6 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 CBZ28817.1 - 6.7e-06 25.4 0.1 0.014 14.6 0.1 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBZ28817.1 - 0.00062 18.9 0.0 0.0011 18.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CBZ28817.1 - 0.0013 18.2 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CBZ28817.1 - 0.0032 16.5 0.1 0.68 8.9 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 CBZ28817.1 - 0.0074 16.2 1.5 0.13 12.2 1.0 2.3 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 CBZ28817.1 - 0.085 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Dynamin family IstB_IS21 PF01695.12 CBZ28817.1 - 0.1 12.0 0.6 2.6 7.4 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 CBZ28817.1 - 0.11 12.0 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 CBZ28817.1 - 0.11 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 CBZ28817.1 - 0.12 12.7 0.1 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBZ28817.1 - 0.29 11.2 2.2 3.5 7.7 1.5 2.3 1 1 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.13 CBZ28819.1 - 8.1e-35 120.2 0.2 1.4e-34 119.5 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RIO1 PF01163.17 CBZ28820.1 - 3e-45 153.8 0.0 5.3e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CBZ28820.1 - 2.1e-32 110.9 0.4 4.9e-31 106.6 0.2 2.3 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 CBZ28820.1 - 2.4e-09 37.3 0.1 3.7e-05 23.5 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CBZ28820.1 - 0.0016 17.5 4.3 0.0027 16.7 0.0 3.0 3 1 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family PSP1 PF04468.7 CBZ28821.1 - 4.4e-07 29.7 0.1 8e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Peptidase_M20 PF01546.23 CBZ28822.1 - 7.5e-28 97.3 0.1 8.8e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ28822.1 - 9.1e-07 28.6 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CBZ28822.1 - 0.0041 16.8 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PLAC8 PF04749.12 CBZ28823.1 - 2e-20 73.3 12.9 3e-20 72.7 9.0 1.3 1 0 0 1 1 1 1 PLAC8 family WD40 PF00400.27 CBZ28824.1 - 4.7e-29 99.1 1.6 5.1e-06 26.1 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBZ28824.1 - 0.043 11.9 0.6 4 5.4 0.1 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PLAC8 PF04749.12 CBZ28825.1 - 3.2e-15 56.5 25.7 4e-15 56.2 17.8 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.12 CBZ28826.1 - 7.2e-16 58.6 26.1 9.2e-16 58.3 18.1 1.1 1 0 0 1 1 1 1 PLAC8 family Kinesin PF00225.18 CBZ28828.1 - 8e-82 274.6 0.0 1.7e-81 273.5 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Mcp5_PH PF12814.2 CBZ28828.1 - 0.00034 20.5 0.0 0.00098 19.0 0.0 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology AAA_13 PF13166.1 CBZ28828.1 - 0.36 9.2 13.8 0.16 10.3 7.6 1.7 2 0 0 2 2 2 0 AAA domain Bap31 PF05529.7 CBZ28828.1 - 2.4 7.5 8.5 5.4 6.4 5.9 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like V_ATPase_I PF01496.14 CBZ28828.1 - 3.5 5.3 7.3 5.3 4.7 5.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family S1-P1_nuclease PF02265.11 CBZ28829.1 - 2.5e-59 200.9 0.0 2.8e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Muskelin_N PF06588.6 CBZ28829.1 - 0.097 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Muskelin N-terminus S1-P1_nuclease PF02265.11 CBZ28830.1 - 5.6e-58 196.5 0.0 6.4e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PseudoU_synth_2 PF00849.17 CBZ28831.1 - 2.1e-34 118.6 0.0 4.9e-33 114.2 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase Rad17 PF03215.10 CBZ28832.1 - 2.8e-08 32.9 0.1 0.00017 20.4 0.0 3.2 3 0 0 3 3 3 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CBZ28832.1 - 0.04 12.9 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CBZ28832.1 - 0.085 13.0 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Flavoprotein PF02441.14 CBZ28833.1 - 3e-42 143.3 0.8 3e-42 143.3 0.6 1.8 2 0 0 2 2 2 1 Flavoprotein PseudoU_synth_1 PF01416.15 CBZ28834.1 - 2.6e-27 95.3 0.0 2e-19 69.9 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pkinase PF00069.20 CBZ28835.1 - 1.9e-30 105.9 0.0 7.5e-13 48.2 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28835.1 - 4.5e-15 55.4 0.0 3.2e-06 26.4 0.1 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28835.1 - 0.13 11.1 0.1 0.25 10.2 0.1 1.3 1 0 0 1 1 1 0 Kinase-like DUF1796 PF08795.5 CBZ28836.1 - 1.4e-67 226.5 0.1 3.9e-67 225.0 0.0 1.8 2 0 0 2 2 2 1 Putative papain-like cysteine peptidase (DUF1796) Kelch_4 PF13418.1 CBZ28837.1 - 3.5e-06 26.6 2.4 0.15 11.8 0.0 5.4 5 0 0 5 5 5 2 Galactose oxidase, central domain PH PF00169.24 CBZ28837.1 - 0.00017 21.7 3.5 0.0045 17.1 0.3 2.9 2 1 0 2 2 2 1 PH domain Kelch_3 PF13415.1 CBZ28837.1 - 0.00081 19.4 0.5 16 5.8 0.0 5.7 5 1 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CBZ28837.1 - 0.0026 17.2 1.0 0.62 9.6 0.1 3.9 4 0 0 4 4 4 1 Kelch motif PH_11 PF15413.1 CBZ28837.1 - 0.032 14.4 1.4 4.4 7.5 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain Actin PF00022.14 CBZ28839.1 - 0.0013 17.2 0.0 0.0023 16.4 0.0 1.3 1 0 0 1 1 1 1 Actin Nop14 PF04147.7 CBZ28839.1 - 0.035 12.0 2.9 0.045 11.6 2.0 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_viral_N PF00242.12 CBZ28839.1 - 0.096 11.7 8.4 0.18 10.8 5.8 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain CDC45 PF02724.9 CBZ28839.1 - 0.27 9.2 2.8 0.41 8.6 2.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.4 CBZ28839.1 - 5.1 5.2 8.3 8.9 4.4 5.8 1.4 1 0 0 1 1 1 0 Transmembrane protein NAD_binding_6 PF08030.7 CBZ28840.1 - 3.5e-15 56.2 0.0 6.9e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CBZ28840.1 - 7.2e-13 48.7 12.0 7.2e-13 48.7 8.3 3.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CBZ28840.1 - 2e-11 43.6 0.0 4.8e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 CBZ28840.1 - 0.0017 18.4 0.0 0.0041 17.1 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CBZ28840.1 - 0.021 15.3 0.0 0.86 10.1 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain E1-E2_ATPase PF00122.15 CBZ28840.1 - 0.34 9.8 2.4 1.2 8.1 1.7 1.9 1 0 0 1 1 1 0 E1-E2 ATPase DUF1077 PF06417.7 CBZ28843.1 - 2.2e-42 143.3 1.3 2.6e-42 143.1 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) PqiA PF04403.8 CBZ28843.1 - 0.048 13.2 0.9 0.064 12.8 0.6 1.2 1 0 0 1 1 1 0 Paraquat-inducible protein A DUF1212 PF06738.7 CBZ28843.1 - 0.12 11.8 0.6 0.48 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) HSP33 PF01430.14 CBZ28844.1 - 1.4e-10 40.8 0.0 8.2e-06 25.1 0.0 2.2 2 0 0 2 2 2 2 Hsp33 protein CRAL_TRIO PF00650.15 CBZ28845.1 - 1.1e-19 70.4 0.0 1.4e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CBZ28845.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CBZ28845.1 - 0.0074 16.4 0.8 0.024 14.7 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF4350 PF14258.1 CBZ28846.1 - 0.032 14.4 0.2 0.45 10.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) DUF2291 PF10054.4 CBZ28846.1 - 0.12 11.6 1.7 0.41 9.8 1.2 2.0 1 1 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) AAA_2 PF07724.9 CBZ28847.1 - 1.5e-07 31.4 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CBZ28847.1 - 6.7e-06 26.2 0.0 2.8e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ28847.1 - 3.7e-05 23.4 0.0 0.0001 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2721 PF11026.3 CBZ28847.1 - 0.00014 21.5 2.5 0.00042 19.9 1.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) AAA_16 PF13191.1 CBZ28847.1 - 0.0009 19.2 0.0 0.028 14.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CBZ28847.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CBZ28847.1 - 0.003 17.4 0.5 0.034 14.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 CBZ28847.1 - 0.034 14.9 0.0 0.092 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Baculo_RING PF05883.6 CBZ28847.1 - 0.056 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RNA_helicase PF00910.17 CBZ28847.1 - 0.24 11.5 0.0 0.54 10.4 0.0 1.6 1 1 0 1 1 1 0 RNA helicase DUF3154 PF11351.3 CBZ28847.1 - 0.33 10.7 0.1 0.33 10.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Ras PF00071.17 CBZ28848.1 - 3.2e-38 130.6 0.0 3.9e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ28848.1 - 1.2e-14 54.8 0.0 2.2e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ28848.1 - 2.5e-10 39.8 0.0 3.3e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ28848.1 - 0.0012 18.0 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 CBZ28848.1 - 0.0018 17.5 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B MMR_HSR1 PF01926.18 CBZ28848.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CBZ28848.1 - 0.026 13.1 0.0 1.2 7.7 0.0 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Ribonuc_red_lgN PF00317.16 CBZ28848.1 - 0.032 14.0 0.0 0.068 12.9 0.0 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain PduV-EutP PF10662.4 CBZ28848.1 - 0.087 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation IncA PF04156.9 CBZ28850.1 - 0.99 8.9 19.2 0.11 12.0 1.9 2.2 2 0 0 2 2 2 0 IncA protein CENP-F_leu_zip PF10473.4 CBZ28850.1 - 1.1 9.1 24.7 0.46 10.3 6.0 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIC PF04977.10 CBZ28850.1 - 3.3 7.2 19.1 1 8.8 0.7 3.3 2 1 1 3 3 3 0 Septum formation initiator DUF4078 PF13300.1 CBZ28850.1 - 4.9 7.3 11.9 0.76 9.9 3.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) CLASP_N PF12348.3 CBZ28853.1 - 1.1e-11 44.6 3.4 7.8e-07 28.6 0.1 4.5 5 0 0 5 5 5 3 CLASP N terminal Cnd1 PF12717.2 CBZ28853.1 - 0.41 10.4 4.3 1 9.1 1.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 IFT46_B_C PF12317.3 CBZ28854.1 - 1.9e-91 305.2 0.5 2.4e-91 304.8 0.3 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Nucleoplasmin PF03066.10 CBZ28854.1 - 0.073 12.5 1.1 0.1 12.1 0.7 1.2 1 0 0 1 1 1 0 Nucleoplasmin TBX PF12598.3 CBZ28854.1 - 0.29 11.5 4.7 0.46 10.8 3.3 1.3 1 0 0 1 1 1 0 T-box transcription factor Pkinase PF00069.20 CBZ28855.1 - 6.4e-31 107.4 0.0 7e-28 97.4 0.0 3.4 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28855.1 - 3.1e-09 36.2 0.0 1.1e-05 24.6 0.0 3.0 2 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CBZ28855.1 - 0.0029 17.3 0.0 0.008 15.9 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family DnaJ PF00226.26 CBZ28856.1 - 7.7e-21 73.5 0.1 1.8e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain TGT PF01702.13 CBZ28857.1 - 2.6e-88 295.3 0.0 3.7e-88 294.8 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase PapD-like PF14874.1 CBZ28858.1 - 3.3e-20 71.9 30.6 0.00027 20.8 0.0 15.0 18 0 0 18 18 17 5 Flagellar-associated PapD-like Motile_Sperm PF00635.21 CBZ28858.1 - 3e-13 49.3 9.5 0.088 12.4 0.0 12.3 15 0 0 15 15 15 2 MSP (Major sperm protein) domain MYCBPAP PF14646.1 CBZ28858.1 - 5.3e-07 28.6 0.0 5.3 5.6 0.0 7.4 10 0 0 10 10 10 2 MYCBP-associated protein family Zeta_toxin PF06414.7 CBZ28858.1 - 0.0002 20.4 0.0 0.00047 19.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin PapD_N PF00345.15 CBZ28858.1 - 0.0022 17.7 0.2 0.47 10.2 0.0 4.6 5 0 0 5 5 5 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain AAA_17 PF13207.1 CBZ28858.1 - 0.003 18.3 0.0 0.0066 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ28858.1 - 0.0073 16.1 0.7 0.021 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Trigger_C PF05698.9 CBZ28858.1 - 0.027 14.3 1.6 0.047 13.5 1.1 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus AAA_22 PF13401.1 CBZ28858.1 - 0.029 14.4 0.0 0.08 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBZ28858.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CBZ28858.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.7 CBZ28858.1 - 0.17 11.5 0.0 0.45 10.1 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 CBZ28858.1 - 0.19 12.0 0.0 0.42 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CBZ28858.1 - 0.38 10.9 0.0 0.78 9.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3449 PF11931.3 CBZ28859.1 - 1.1e-44 152.3 0.5 2.2e-44 151.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) FYVE PF01363.16 CBZ28861.1 - 1.1e-11 44.4 8.7 1.4e-11 44.0 3.8 2.5 2 0 0 2 2 2 1 FYVE zinc finger PI3_PI4_kinase PF00454.22 CBZ28861.1 - 1.9e-09 37.3 0.3 4.5e-07 29.5 0.0 2.4 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase OrfB_Zn_ribbon PF07282.6 CBZ28861.1 - 0.09 12.4 2.9 0.34 10.5 2.0 2.0 1 0 0 1 1 1 0 Putative transposase DNA-binding domain C_tripleX PF02363.14 CBZ28862.1 - 0.16 12.0 0.7 0.36 10.9 0.5 1.6 1 0 0 1 1 1 0 Cysteine rich repeat ABM PF03992.11 CBZ28864.1 - 0.1 12.6 0.4 1.5 8.9 0.0 2.0 1 1 1 2 2 2 0 Antibiotic biosynthesis monooxygenase AAA_18 PF13238.1 CBZ28865.1 - 7.5e-26 90.9 0.1 1.3e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ28865.1 - 1.1e-11 45.6 0.2 2.2e-11 44.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ28865.1 - 2.7e-06 27.2 0.2 0.00034 20.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CBZ28865.1 - 1.2e-05 25.5 0.1 1.7e-05 25.0 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CBZ28865.1 - 7.1e-05 22.8 3.1 0.00067 19.6 2.1 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ28865.1 - 0.00038 19.5 0.0 0.00057 19.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBZ28865.1 - 0.00075 19.6 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 CBZ28865.1 - 0.00097 19.0 0.3 0.2 11.5 0.0 2.2 1 1 0 2 2 2 1 Adenylate kinase Zeta_toxin PF06414.7 CBZ28865.1 - 0.00097 18.2 0.3 0.0021 17.1 0.0 1.7 2 1 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 CBZ28865.1 - 0.0014 18.3 0.0 0.0039 16.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 CBZ28865.1 - 0.0015 17.5 0.1 0.0019 17.2 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SKI PF01202.17 CBZ28865.1 - 0.0018 18.1 4.5 0.015 15.1 3.1 2.1 1 1 0 1 1 1 1 Shikimate kinase Parvo_NS1 PF01057.12 CBZ28865.1 - 0.0052 15.7 0.0 0.0098 14.7 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CBZ28865.1 - 0.0066 16.0 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ28865.1 - 0.0072 16.0 0.0 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CBZ28865.1 - 0.0081 16.3 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 CBZ28865.1 - 0.0083 16.1 0.0 0.018 15.0 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain TIP49 PF06068.8 CBZ28865.1 - 0.009 14.7 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 CBZ28865.1 - 0.01 15.5 2.5 0.019 14.6 0.1 2.4 1 1 2 3 3 3 0 NTPase ABC_tran PF00005.22 CBZ28865.1 - 0.011 16.0 1.3 0.064 13.5 0.9 2.0 1 1 0 1 1 1 0 ABC transporter CoaE PF01121.15 CBZ28865.1 - 0.011 15.1 0.7 0.34 10.2 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase KaiC PF06745.8 CBZ28865.1 - 0.012 14.7 1.0 0.017 14.2 0.1 1.7 2 0 0 2 2 2 0 KaiC dNK PF01712.14 CBZ28865.1 - 0.013 15.4 0.2 0.024 14.5 0.1 1.5 1 1 0 1 1 1 0 Deoxynucleoside kinase Mg_chelatase PF01078.16 CBZ28865.1 - 0.014 14.5 0.1 0.042 13.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.5 CBZ28865.1 - 0.015 14.4 0.1 0.041 13.1 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 IstB_IS21 PF01695.12 CBZ28865.1 - 0.016 14.6 0.3 0.037 13.4 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 CBZ28865.1 - 0.017 14.5 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.6 CBZ28865.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_14 PF13173.1 CBZ28865.1 - 0.032 14.1 0.1 0.068 13.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 CBZ28865.1 - 0.037 13.6 2.6 0.52 9.9 0.0 2.8 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein KAP_NTPase PF07693.9 CBZ28865.1 - 0.04 12.9 0.0 0.07 12.1 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain Cytidylate_kin2 PF13189.1 CBZ28865.1 - 0.045 13.6 1.7 0.32 10.8 0.1 2.6 1 1 1 2 2 2 0 Cytidylate kinase-like family Thymidylate_kin PF02223.12 CBZ28865.1 - 0.048 13.0 0.9 6 6.1 0.0 2.4 2 1 0 2 2 2 0 Thymidylate kinase Arch_ATPase PF01637.13 CBZ28865.1 - 0.048 13.3 0.1 0.12 12.0 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 CBZ28865.1 - 0.05 13.0 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CBZ28865.1 - 0.056 12.3 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_3 PF07726.6 CBZ28865.1 - 0.061 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sars6 PF12133.3 CBZ28865.1 - 0.092 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus NACHT PF05729.7 CBZ28865.1 - 0.1 12.2 0.1 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.15 CBZ28865.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase cobW PF02492.14 CBZ28865.1 - 0.11 11.9 0.2 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CBZ28865.1 - 0.13 11.9 1.0 0.28 10.8 0.1 2.1 2 2 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 CBZ28865.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 CBZ28865.1 - 0.16 11.5 1.0 6.6 6.1 0.1 2.1 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 CBZ28865.1 - 0.17 11.3 1.3 0.28 10.6 0.1 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 CBZ28865.1 - 0.27 11.5 2.8 1.6 9.0 1.9 2.1 1 1 0 1 1 1 0 AAA domain Helitron_like_N PF14214.1 CBZ28866.1 - 0.2 11.3 0.1 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus CoA_trans PF01144.18 CBZ28868.1 - 8.9e-102 338.8 0.1 1.1e-60 204.5 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CBZ28868.1 - 0.009 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 CBZ28869.1 - 3.4e-97 323.8 0.2 2.3e-60 203.4 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CBZ28869.1 - 2.5e-05 23.9 0.0 4.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain PseudoU_synth_2 PF00849.17 CBZ28871.1 - 1.2e-22 80.5 0.8 2.9e-13 49.9 0.1 3.0 3 0 0 3 3 3 2 RNA pseudouridylate synthase S4 PF01479.20 CBZ28871.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 S4 domain TPR_MLP1_2 PF07926.7 CBZ28872.1 - 0.0098 15.6 20.3 1.4 8.6 0.4 3.4 3 0 0 3 3 3 3 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 CBZ28872.1 - 0.45 10.2 9.3 15 5.2 0.0 3.9 4 0 0 4 4 4 0 Laminin Domain II DUF1664 PF07889.7 CBZ28872.1 - 1.5 8.6 8.6 3.1 7.5 0.1 3.6 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) WXG100 PF06013.7 CBZ28872.1 - 2.1 8.3 8.6 3.7 7.6 0.0 4.0 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Med9 PF07544.8 CBZ28872.1 - 7.9 6.2 11.1 7.7 6.3 0.4 3.6 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 zf-C2H2_2 PF12756.2 CBZ28874.1 - 3.3e-20 72.0 9.2 6.6e-14 51.8 2.4 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 CBZ28874.1 - 0.00049 20.1 14.4 0.027 14.5 0.6 4.1 3 1 1 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CBZ28874.1 - 0.0058 16.8 8.2 0.78 10.2 0.9 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CBZ28874.1 - 0.016 15.5 11.6 1.4 9.4 0.0 4.6 4 1 0 4 4 4 0 Zinc finger, C2H2 type Rubredoxin PF00301.15 CBZ28874.1 - 0.075 12.9 0.2 0.075 12.9 0.2 3.1 4 0 0 4 4 4 0 Rubredoxin DUF3279 PF11682.3 CBZ28874.1 - 2.1 7.9 6.8 3 7.4 1.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3279) PC_rep PF01851.17 CBZ28876.1 - 0.01 16.0 5.5 1e+02 3.4 0.1 6.7 7 0 0 7 7 7 0 Proteasome/cyclosome repeat IFT20 PF14931.1 CBZ28877.1 - 6.1e-39 132.6 8.8 6.8e-39 132.4 6.1 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 VQ PF05678.9 CBZ28877.1 - 0.059 12.4 2.5 1.3 8.1 0.1 2.7 3 0 0 3 3 3 0 VQ motif 4HB_MCP_1 PF12729.2 CBZ28877.1 - 0.12 11.6 3.4 0.15 11.3 1.9 1.5 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction Snapin_Pallidin PF14712.1 CBZ28877.1 - 0.44 10.8 7.1 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 Snapin/Pallidin Mannosyl_trans PF05007.8 CBZ28880.1 - 1.8e-82 276.8 9.5 2.5e-82 276.3 6.6 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) DUF2029 PF09594.5 CBZ28880.1 - 6.4e-12 45.4 13.1 6.4e-12 45.4 9.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2029) PIG-U PF06728.8 CBZ28880.1 - 5.3e-10 38.7 16.3 1.6e-09 37.1 11.1 1.8 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U Peptidase_C2 PF00648.16 CBZ28881.1 - 3.7e-24 85.2 0.1 3e-11 42.8 0.0 3.9 4 0 0 4 4 4 3 Calpain family cysteine protease Calpain_III PF01067.17 CBZ28881.1 - 1.1e-08 34.7 0.0 0.0017 18.0 0.0 3.3 3 0 0 3 3 3 2 Calpain large subunit, domain III LRR_6 PF13516.1 CBZ28881.1 - 0.00013 21.6 3.5 1.9 8.8 0.1 3.7 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 CBZ28881.1 - 0.03 13.9 6.2 0.086 12.4 2.0 2.4 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ28881.1 - 0.042 13.8 5.3 27 5.3 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 CBZ28881.1 - 0.23 11.7 2.5 48 4.7 0.1 3.7 3 0 0 3 3 3 0 Leucine rich repeat LRR_8 PF13855.1 CBZ28881.1 - 1.5 8.6 5.9 27 4.5 2.3 2.6 1 1 1 2 2 2 0 Leucine rich repeat Cytochrom_B561 PF03188.11 CBZ28882.1 - 6.3e-12 45.5 5.1 1.3e-11 44.5 3.5 1.5 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 PepSY_TM_2 PF13703.1 CBZ28882.1 - 0.11 12.6 3.1 3.1 8.0 0.0 2.9 1 1 2 3 3 3 0 PepSY-associated TM helix DUF2099 PF09872.4 CBZ28883.1 - 0.066 12.2 0.0 0.2 10.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2099) DUF814 PF05670.8 CBZ28885.1 - 1.3e-21 76.2 0.0 2.3e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Atg14 PF10186.4 CBZ28885.1 - 0.26 10.1 6.9 0.36 9.7 4.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1764 PF08576.5 CBZ28885.1 - 3.6 8.4 8.9 5.6 7.7 6.2 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) AAA_16 PF13191.1 CBZ28886.1 - 0.0018 18.3 0.1 0.0049 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CBZ28886.1 - 0.007 16.0 0.5 0.031 14.0 0.2 2.2 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 CBZ28886.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 CBZ28886.1 - 0.013 15.6 0.0 0.052 13.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CBZ28886.1 - 0.036 13.4 0.2 0.099 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CBZ28886.1 - 0.05 13.0 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.12 CBZ28886.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_10 PF12846.2 CBZ28886.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 CBZ28886.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fe-ADH PF00465.14 CBZ28887.1 - 8.1e-108 360.3 0.7 9e-108 360.1 0.5 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 CBZ28887.1 - 1.5e-19 70.3 0.1 3e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Flagellin_N PF00669.15 CBZ28888.1 - 0.0023 17.7 3.5 0.0057 16.4 2.4 1.6 1 0 0 1 1 1 1 Bacterial flagellin N-terminal helical region DUF1664 PF07889.7 CBZ28888.1 - 0.0027 17.4 0.7 0.0069 16.1 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF148 PF02520.12 CBZ28888.1 - 0.007 16.1 3.1 0.012 15.4 2.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF148 OmpH PF03938.9 CBZ28888.1 - 0.01 15.8 1.7 0.02 14.8 1.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Apolipoprotein PF01442.13 CBZ28888.1 - 0.017 14.6 1.2 0.017 14.6 0.8 1.8 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Reo_sigmaC PF04582.7 CBZ28888.1 - 0.023 13.8 0.2 0.038 13.1 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 CBZ28888.1 - 0.045 13.5 0.6 0.099 12.4 0.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 CBZ28888.1 - 0.051 13.9 2.8 0.23 11.9 2.0 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) FlgN PF05130.7 CBZ28888.1 - 0.063 13.5 6.0 0.074 13.2 2.9 2.0 2 0 0 2 2 2 0 FlgN protein Transpep_BrtH PF14399.1 CBZ28888.1 - 0.082 12.1 1.2 0.16 11.2 0.8 1.4 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase Salp15 PF12115.3 CBZ28888.1 - 0.12 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Syntaxin PF00804.20 CBZ28888.1 - 0.14 12.3 1.5 0.3 11.2 1.0 1.5 1 0 0 1 1 1 0 Syntaxin HisKA_3 PF07730.8 CBZ28888.1 - 0.14 12.4 1.7 0.74 10.2 1.2 2.3 1 0 0 1 1 1 0 Histidine kinase Oligomerisation PF02410.10 CBZ28890.1 - 1.2e-14 54.0 0.9 1.9e-14 53.4 0.6 1.3 1 0 0 1 1 1 1 Oligomerisation domain Pkinase PF00069.20 CBZ28891.1 - 3.1e-50 170.7 0.0 6e-37 127.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28891.1 - 1.8e-34 119.0 0.0 4e-27 94.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Beta_helix PF13229.1 CBZ28891.1 - 1.3e-28 99.7 14.0 1.5e-16 60.5 0.5 3.2 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.8 CBZ28891.1 - 1.3e-25 89.9 0.4 2.1e-15 56.5 0.4 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Kinase-like PF14531.1 CBZ28891.1 - 8.7e-06 24.8 0.1 3.7e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like zf-B_box PF00643.19 CBZ28891.1 - 0.1 12.4 11.6 0.32 10.9 8.1 1.8 1 0 0 1 1 1 0 B-box zinc finger APH PF01636.18 CBZ28891.1 - 0.12 12.1 0.0 0.88 9.2 0.0 2.4 3 1 0 3 3 3 0 Phosphotransferase enzyme family Patatin PF01734.17 CBZ28892.1 - 2.2e-23 83.2 0.0 2.2e-23 83.2 0.0 2.2 2 1 0 3 3 3 1 Patatin-like phospholipase DUF3336 PF11815.3 CBZ28892.1 - 5e-12 45.5 0.0 8.7e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) WD40 PF00400.27 CBZ28893.1 - 3.5e-15 55.1 4.9 0.035 14.0 0.0 7.3 8 0 0 8 8 8 6 WD domain, G-beta repeat IBR PF01485.16 CBZ28895.1 - 5.2e-15 55.0 50.0 1.4e-09 37.7 9.5 4.5 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 CBZ28895.1 - 6.9e-07 29.0 41.1 0.00048 19.8 8.9 3.9 4 0 0 4 4 4 3 Ring finger domain zf-RING_5 PF14634.1 CBZ28895.1 - 0.014 15.0 12.4 0.014 15.0 8.6 4.3 2 1 1 3 3 3 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CBZ28895.1 - 0.036 13.7 37.7 0.055 13.1 7.5 3.7 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 CBZ28896.1 - 7.5e-25 86.3 0.0 1.2e-14 53.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ28896.1 - 1.5e-15 56.8 0.0 1.3e-08 34.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ28896.1 - 9.8e-06 25.3 0.0 0.22 11.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TIR-like PF10137.4 CBZ28896.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Mito_fiss_reg PF05308.6 CBZ28896.1 - 3.8 6.8 10.0 0.069 12.5 2.1 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator RRM_1 PF00076.17 CBZ28897.1 - 3.4e-23 81.0 2.7 2.5e-14 52.6 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ28897.1 - 6.6e-18 64.4 0.0 9.7e-09 35.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ28897.1 - 5.5e-07 29.3 0.0 0.00028 20.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 CBZ28898.1 - 4.7e-08 32.5 0.5 6.6e-08 32.0 0.4 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ28898.1 - 0.021 14.8 1.0 0.042 13.8 0.7 1.5 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DnaJ PF00226.26 CBZ28899.1 - 3.9e-16 58.5 0.4 8.5e-16 57.4 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4339 PF14237.1 CBZ28899.1 - 4.1e-16 58.2 0.3 9.7e-16 57.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4339) CDC14 PF08045.6 CBZ28899.1 - 0.039 13.0 2.7 0.043 12.9 0.5 2.0 2 0 0 2 2 2 0 Cell division control protein 14, SIN component DUF155 PF02582.9 CBZ28900.1 - 8.4e-20 71.3 0.0 2e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 APH PF01636.18 CBZ28901.1 - 0.044 13.5 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Replicase PF03090.12 CBZ28901.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Replicase family Mito_carr PF00153.22 CBZ28902.1 - 5.1e-11 42.1 11.1 0.0019 17.8 0.0 5.1 6 0 0 6 6 6 4 Mitochondrial carrier protein Polysacc_synt_C PF14667.1 CBZ28902.1 - 0.072 12.8 0.4 1.7 8.4 0.2 2.7 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain zf-C2H2_2 PF12756.2 CBZ28903.1 - 3.8e-24 84.7 10.6 6.4e-19 67.9 1.0 3.2 2 1 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CBZ28903.1 - 5.2e-09 35.9 7.5 3.1e-06 27.1 0.6 4.0 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CBZ28903.1 - 9.4e-09 34.8 5.2 0.0019 18.0 1.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 CBZ28903.1 - 3.4e-05 23.8 15.3 0.00082 19.4 1.8 4.1 4 1 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CBZ28903.1 - 0.0052 17.0 16.1 0.027 14.7 1.7 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBZ28903.1 - 0.024 14.9 17.9 0.12 12.7 1.2 4.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-FCS PF06467.9 CBZ28903.1 - 0.93 9.1 4.6 0.69 9.6 0.2 2.9 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif C1_1 PF00130.17 CBZ28903.1 - 1.5 8.6 0.0 1.5 8.6 0.0 3.2 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) E1-E2_ATPase PF00122.15 CBZ28904.1 - 7.2e-13 48.1 0.0 1.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CBZ28904.1 - 4.2e-12 46.9 0.6 7.7e-07 29.7 0.6 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ28904.1 - 2e-08 34.6 0.0 3.5e-07 30.5 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ28904.1 - 3.2e-07 30.2 0.0 7.6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBZ28904.1 - 0.016 14.8 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase LRR_4 PF12799.2 CBZ28905.1 - 7.4e-21 73.3 8.1 3.7e-07 29.6 0.0 6.7 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ28905.1 - 6.3e-14 51.4 14.5 9.9e-07 28.4 0.1 5.8 4 2 3 7 7 7 5 Leucine rich repeat LRR_6 PF13516.1 CBZ28905.1 - 0.00022 20.9 8.5 8.6 6.7 0.0 7.8 8 1 1 9 9 9 1 Leucine Rich repeat LRR_7 PF13504.1 CBZ28905.1 - 0.0003 20.5 26.9 2.6 8.6 0.3 10.2 11 0 0 11 11 11 2 Leucine rich repeat LRR_1 PF00560.28 CBZ28905.1 - 0.0017 18.1 21.3 7.9 6.9 0.2 8.7 9 1 0 9 9 9 3 Leucine Rich Repeat LRR_9 PF14580.1 CBZ28905.1 - 0.033 13.7 0.3 2.5 7.6 0.0 2.8 2 1 0 2 2 2 0 Leucine-rich repeat TTL PF03133.10 CBZ28906.1 - 6.9e-50 169.6 0.1 1.7e-30 106.0 0.0 3.1 2 1 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ28906.1 - 0.00011 21.0 0.0 0.3 9.8 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp CP_ATPgrasp_1 PF04174.8 CBZ28906.1 - 0.1 11.2 0.0 0.21 10.1 0.0 1.4 1 0 0 1 1 1 0 A circularly permuted ATPgrasp Dala_Dala_lig_C PF07478.8 CBZ28906.1 - 0.15 11.4 0.1 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Helicase_C PF00271.26 CBZ28907.1 - 3.3e-14 52.5 0.1 6e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ28907.1 - 3e-13 49.6 0.0 2.3e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase MRF_C1 PF13887.1 CBZ28907.1 - 0.045 12.7 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 OmpH PF03938.9 CBZ28908.1 - 1.6 8.6 14.1 4.3 7.2 9.7 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SET PF00856.23 CBZ28910.1 - 6.5e-07 29.7 0.0 2.4e-05 24.6 0.0 2.2 2 1 0 2 2 2 2 SET domain TPR_MLP1_2 PF07926.7 CBZ28912.1 - 0.0095 15.6 3.2 0.0095 15.6 2.2 2.2 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein zf-C2H2 PF00096.21 CBZ28912.1 - 0.018 15.3 0.1 0.046 14.0 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CBZ28912.1 - 0.12 12.7 0.9 0.42 11.0 0.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger APG6 PF04111.7 CBZ28912.1 - 0.31 10.0 2.3 0.54 9.2 1.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Pyridoxal_deC PF00282.14 CBZ28913.1 - 9.8e-21 73.6 0.0 2e-20 72.5 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 CBZ28913.1 - 3.9e-11 42.2 0.0 1.3e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CBZ28913.1 - 0.049 12.6 0.0 0.097 11.6 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-C3HC4_4 PF15227.1 CBZ28914.1 - 5.2e-09 35.8 7.9 5.2e-09 35.8 5.5 3.8 3 2 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CBZ28914.1 - 8.5e-09 34.9 7.4 8.5e-09 34.9 5.1 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.19 CBZ28914.1 - 1e-07 31.6 37.4 6.4e-07 29.1 4.5 4.2 4 0 0 4 4 4 2 B-box zinc finger zf-C3HC4_2 PF13923.1 CBZ28914.1 - 1.3e-05 25.0 8.2 1.3e-05 25.0 5.7 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ28914.1 - 0.00013 21.6 8.8 0.00013 21.6 6.1 3.5 3 0 0 3 3 3 1 zinc-RING finger domain Spc7 PF08317.6 CBZ28914.1 - 0.01 14.5 0.3 0.014 14.0 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-RING_UBOX PF13445.1 CBZ28914.1 - 2.3 7.9 18.0 0.032 13.9 2.9 3.2 2 1 0 2 2 2 0 RING-type zinc-finger Arf PF00025.16 CBZ28915.1 - 1.2e-49 167.8 0.0 1.3e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBZ28915.1 - 1e-17 63.9 0.0 1.3e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBZ28915.1 - 1.9e-11 43.6 0.0 2.4e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ28915.1 - 3.4e-11 43.6 0.0 4.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBZ28915.1 - 6.8e-11 42.1 0.0 8.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 CBZ28915.1 - 1.7e-09 36.8 0.0 2.7e-06 26.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBZ28915.1 - 1.1e-06 27.9 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ28915.1 - 2e-05 24.1 0.0 0.00013 21.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CBZ28915.1 - 9.8e-05 21.6 0.0 0.00019 20.7 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 CBZ28915.1 - 0.042 13.5 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase cobW PF02492.14 CBZ28915.1 - 0.042 13.2 0.1 2.7 7.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CdhD PF03599.11 CBZ28915.1 - 0.055 11.9 0.0 0.075 11.5 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit AAA_14 PF13173.1 CBZ28915.1 - 0.13 12.1 0.0 0.92 9.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 CBZ28916.1 - 1.7 7.7 9.5 0.33 10.0 0.1 2.6 1 1 1 3 3 3 0 Reovirus sigma C capsid protein OpgC_C PF10129.4 CBZ28918.1 - 0.003 16.2 2.0 0.0039 15.9 1.4 1.1 1 0 0 1 1 1 1 OpgC protein Clp1 PF06807.9 CBZ28919.1 - 5.9e-13 49.0 0.0 1.8e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 PTH2 PF01981.11 CBZ28920.1 - 2.6e-11 43.2 0.2 5.6e-11 42.1 0.1 1.6 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 TPR_11 PF13414.1 CBZ28922.1 - 0.00013 21.5 0.0 0.0039 16.8 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 CBZ28922.1 - 0.0036 17.0 0.1 1.4 8.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ28922.1 - 0.1 12.5 0.2 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ28922.1 - 0.1 12.3 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2256 PF10013.4 CBZ28922.1 - 2.4 8.0 4.6 3.7 7.3 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DnaJ PF00226.26 CBZ28923.1 - 6.3e-14 51.4 0.0 1.3e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Plasmodium_Vir PF05795.6 CBZ28923.1 - 0.00026 20.2 0.0 0.00035 19.9 0.0 1.1 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Phage_DsbA PF11126.3 CBZ28923.1 - 0.48 10.5 3.3 9.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator DsbA HSP70 PF00012.15 CBZ28924.1 - 4.4e-245 814.2 4.2 5.1e-245 814.0 2.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ28924.1 - 7.3e-14 51.0 0.4 1.7e-12 46.6 0.1 2.5 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.6 CBZ28924.1 - 0.00044 19.2 0.5 0.68 8.8 0.0 3.2 2 1 1 3 3 3 2 StbA protein PIN_3 PF13470.1 CBZ28924.1 - 0.015 15.9 0.4 0.4 11.3 0.0 2.4 2 0 0 2 2 2 0 PIN domain FtsA PF14450.1 CBZ28924.1 - 0.034 13.9 9.8 0.63 9.8 0.0 4.7 4 1 0 4 4 4 0 Cell division protein FtsA Hydantoinase_A PF01968.13 CBZ28924.1 - 0.3 10.1 10.0 2 7.4 0.2 3.8 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase DUF4404 PF14357.1 CBZ28924.1 - 0.34 11.3 2.2 0.68 10.3 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Taeniidae_ag PF05596.6 CBZ28924.1 - 0.34 10.7 3.5 0.31 10.8 0.5 2.3 2 0 0 2 2 2 0 Taeniidae antigen HSP70 PF00012.15 CBZ28925.1 - 9.3e-148 492.7 0.6 1.1e-147 492.6 0.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ28925.1 - 8.5e-14 50.8 0.2 2.8e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein StbA PF06406.6 CBZ28925.1 - 0.02 13.8 0.1 0.18 10.7 0.0 2.1 2 0 0 2 2 2 0 StbA protein DP PF08781.5 CBZ28925.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription factor DP FtsA PF14450.1 CBZ28925.1 - 0.094 12.5 8.0 7.8 6.3 0.6 4.0 3 1 0 3 3 3 0 Cell division protein FtsA PIN_3 PF13470.1 CBZ28925.1 - 0.099 13.3 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 PIN domain Hydantoinase_A PF01968.13 CBZ28925.1 - 0.13 11.3 4.5 0.9 8.5 0.2 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase HSP70 PF00012.15 CBZ28926.1 - 5.6e-259 860.1 8.5 5.6e-259 860.1 5.9 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ28926.1 - 6.1e-14 51.3 0.6 1.3e-12 46.9 0.1 2.6 2 1 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CBZ28926.1 - 0.0079 16.0 12.0 0.65 9.8 0.0 4.8 4 1 0 4 4 4 3 Cell division protein FtsA PIN_3 PF13470.1 CBZ28926.1 - 0.11 13.2 3.3 0.44 11.2 0.0 2.6 2 1 0 2 2 2 0 PIN domain Taeniidae_ag PF05596.6 CBZ28926.1 - 0.2 11.4 3.1 0.22 11.3 0.4 2.3 2 0 0 2 2 2 0 Taeniidae antigen Hydantoinase_A PF01968.13 CBZ28926.1 - 0.91 8.5 11.6 2.2 7.3 0.2 3.7 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase AAA PF00004.24 CBZ28930.1 - 4.5e-47 159.5 0.0 1.1e-40 138.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ28930.1 - 1.7e-07 31.4 0.0 0.014 15.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ28930.1 - 4.1e-05 23.6 6.7 0.25 11.3 0.0 4.3 3 2 1 4 4 3 2 AAA ATPase domain RuvB_N PF05496.7 CBZ28930.1 - 0.00017 20.7 0.0 0.00097 18.2 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CBZ28930.1 - 0.00017 21.3 0.1 0.049 13.3 0.0 3.3 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CBZ28930.1 - 0.00034 20.5 0.2 0.85 9.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CBZ28930.1 - 0.00037 19.9 2.3 0.87 8.9 0.0 4.1 2 2 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 CBZ28930.1 - 0.00092 18.6 0.1 0.13 11.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 CBZ28930.1 - 0.0013 18.4 0.0 1.6 8.3 0.0 2.7 3 0 0 3 3 2 2 NACHT domain RNA_helicase PF00910.17 CBZ28930.1 - 0.0029 17.7 0.0 0.32 11.1 0.0 2.8 3 0 0 3 3 2 1 RNA helicase Vps4_C PF09336.5 CBZ28930.1 - 0.0033 17.2 0.0 0.015 15.1 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 CBZ28930.1 - 0.0038 16.0 0.0 0.007 15.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CBZ28930.1 - 0.0039 16.3 0.0 0.064 12.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 CBZ28930.1 - 0.012 15.5 0.0 0.039 13.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 CBZ28930.1 - 0.014 14.4 0.1 0.11 11.6 0.0 2.4 3 0 0 3 3 3 0 Zeta toxin AAA_17 PF13207.1 CBZ28930.1 - 0.031 15.0 0.0 0.44 11.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CBZ28930.1 - 0.032 14.5 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Sigma54_activ_2 PF14532.1 CBZ28930.1 - 0.049 13.6 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 CBZ28930.1 - 0.055 13.3 0.0 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CBZ28930.1 - 0.071 12.7 0.0 9.8 5.7 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase Sigma54_activat PF00158.21 CBZ28930.1 - 0.085 12.3 0.0 9.4 5.6 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 CBZ28930.1 - 0.17 11.4 0.0 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 CBZ28930.1 - 0.19 10.3 0.0 0.29 9.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein HSP70 PF00012.15 CBZ28931.1 - 1.7e-259 861.8 8.7 2e-259 861.6 6.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ28931.1 - 2.2e-13 49.5 0.8 4.4e-12 45.2 0.2 2.6 2 1 0 2 2 2 1 MreB/Mbl protein PIN_3 PF13470.1 CBZ28931.1 - 0.0037 17.9 0.4 0.095 13.3 0.0 2.4 2 0 0 2 2 2 1 PIN domain FtsA PF14450.1 CBZ28931.1 - 0.0081 15.9 12.2 0.64 9.8 0.0 4.8 4 1 0 4 4 4 3 Cell division protein FtsA Taeniidae_ag PF05596.6 CBZ28931.1 - 0.2 11.5 3.1 0.22 11.3 0.4 2.3 2 0 0 2 2 2 0 Taeniidae antigen Hydantoinase_A PF01968.13 CBZ28931.1 - 0.37 9.8 10.3 2.1 7.3 0.2 3.7 4 0 0 4 4 4 0 Hydantoinase/oxoprolinase DUF4404 PF14357.1 CBZ28931.1 - 0.63 10.4 4.3 0.56 10.6 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Cofilin_ADF PF00241.15 CBZ28933.1 - 0.00041 20.2 0.0 0.0089 15.9 0.0 2.3 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein MCPVI PF02993.9 CBZ28933.1 - 0.21 11.7 3.1 0.39 10.8 0.7 2.0 2 0 0 2 2 2 0 Minor capsid protein VI Reticulon PF02453.12 CBZ28934.1 - 1.6e-34 118.9 8.1 1.9e-34 118.7 5.6 1.1 1 0 0 1 1 1 1 Reticulon PrgI PF12666.2 CBZ28934.1 - 0.014 15.5 10.3 0.075 13.1 0.9 2.3 1 1 1 2 2 2 0 PrgI family protein PRT_C PF08372.5 CBZ28934.1 - 0.079 12.4 3.2 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal ABC_tran_2 PF12848.2 CBZ28934.1 - 0.35 10.7 2.5 0.54 10.1 1.7 1.2 1 0 0 1 1 1 0 ABC transporter DUF2628 PF10947.3 CBZ28934.1 - 1.8 8.3 6.8 7.1 6.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) TMA7 PF09072.5 CBZ28934.1 - 5 7.6 5.9 5.5 7.5 2.1 2.0 1 1 1 2 2 2 0 Translation machinery associated TMA7 Pex24p PF06398.6 CBZ28934.1 - 5.6 5.6 9.8 8.3 5.0 0.9 1.8 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin DUF3784 PF12650.2 CBZ28934.1 - 8.4 6.4 8.9 5.7 6.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Leu_Phe_trans PF03588.9 CBZ28935.1 - 3.3e-05 23.0 0.1 0.25 10.4 0.0 2.5 3 0 0 3 3 3 2 Leucyl/phenylalanyl-tRNA protein transferase FTHFS PF01268.14 CBZ28936.1 - 1.5e-258 858.3 0.1 1.7e-258 858.1 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase RRM_1 PF00076.17 CBZ28937.1 - 6.9e-16 57.6 0.0 1.4e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ28937.1 - 2.7e-14 52.8 0.0 4.7e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ28937.1 - 7.5e-08 32.1 0.2 1.7e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ28937.1 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif AAA PF00004.24 CBZ28940.1 - 1.4e-13 51.1 0.0 2.8e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CBZ28940.1 - 5.1e-10 39.1 0.0 9.7e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CBZ28940.1 - 1.4e-08 34.5 0.0 2.1e-07 30.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 CBZ28940.1 - 6.7e-06 26.2 0.0 6.2e-05 23.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ28940.1 - 1.1e-05 24.5 0.0 3.3e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 CBZ28940.1 - 1.4e-05 24.8 0.0 3.5e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ28940.1 - 1.4e-05 25.1 1.5 0.0013 18.7 0.0 3.0 1 1 1 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 CBZ28940.1 - 5e-05 22.9 0.0 0.00016 21.3 0.0 1.9 2 0 0 2 2 1 1 Part of AAA domain Rad17 PF03215.10 CBZ28940.1 - 7.6e-05 21.5 0.0 0.00065 18.5 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DUF2075 PF09848.4 CBZ28940.1 - 0.00038 19.5 0.0 0.00051 19.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CBZ28940.1 - 0.0051 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_33 PF13671.1 CBZ28940.1 - 0.0057 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CBZ28940.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CBZ28940.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBZ28940.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 CBZ28940.1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CBZ28940.1 - 0.031 13.4 0.2 0.075 12.1 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CBZ28940.1 - 0.033 13.6 0.2 0.55 9.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain DEAD PF00270.24 CBZ28940.1 - 0.048 13.1 0.0 0.86 9.0 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF815 PF05673.8 CBZ28940.1 - 0.052 12.4 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 CBZ28940.1 - 0.077 12.5 0.0 0.17 11.3 0.0 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 CBZ28940.1 - 0.12 11.8 0.0 0.4 10.1 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 CBZ28940.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 CBZ28940.1 - 0.16 11.6 0.0 0.76 9.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CLASP_N PF12348.3 CBZ28941.1 - 0.043 13.1 0.0 0.29 10.4 0.0 2.2 3 0 0 3 3 3 0 CLASP N terminal ubiquitin PF00240.18 CBZ28943.1 - 0.0051 16.1 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family IL10 PF00726.12 CBZ28943.1 - 0.13 11.5 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Interleukin 10 TPR_12 PF13424.1 CBZ28944.1 - 2.9e-06 27.1 3.5 0.0011 18.9 0.7 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF3156 PF11354.3 CBZ28944.1 - 0.095 12.0 0.1 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3156) TPR_10 PF13374.1 CBZ28944.1 - 0.1 12.5 3.1 5.9 6.9 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ28944.1 - 0.32 10.6 4.3 0.33 10.6 0.6 2.7 2 1 1 3 3 3 0 TPR repeat TPT PF03151.11 CBZ28946.1 - 8.6e-19 67.6 7.1 8.6e-19 67.6 4.9 3.2 1 1 2 3 3 3 1 Triose-phosphate Transporter family EmrE PF13536.1 CBZ28946.1 - 0.0016 18.5 19.0 0.038 14.1 3.7 3.5 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 CBZ28946.1 - 0.0092 16.0 10.2 0.0092 16.0 7.1 3.4 1 1 1 3 3 3 1 EamA-like transporter family SH3_9 PF14604.1 CBZ28947.1 - 1.1e-06 28.0 0.0 1.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CBZ28947.1 - 3.9e-06 26.2 0.0 5.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CBZ28947.1 - 5.8e-05 22.3 0.0 0.00011 21.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Tmemb_cc2 PF10267.4 CBZ28947.1 - 0.097 11.2 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein LRR_6 PF13516.1 CBZ28948.1 - 0.012 15.5 0.0 1.1 9.5 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat GRAM PF02893.15 CBZ28950.1 - 9.5e-08 31.4 0.0 1.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain SPA PF08616.5 CBZ28951.1 - 4.1e-29 100.5 0.0 8.2e-29 99.6 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 CBZ28951.1 - 0.00024 19.7 0.0 0.041 12.3 0.0 2.2 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.4 CBZ28951.1 - 0.0026 17.1 0.0 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 CBZ28951.1 - 0.04 13.6 0.9 0.069 12.8 0.0 1.9 2 1 0 2 2 2 0 DENN (AEX-3) domain TPR_11 PF13414.1 CBZ28952.1 - 9.2e-28 95.7 4.4 1.8e-19 69.1 1.6 2.8 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBZ28952.1 - 1.6e-26 90.7 8.3 1.4e-08 33.9 0.7 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ28952.1 - 3.3e-19 67.1 14.0 3.1e-07 29.7 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ28952.1 - 1.3e-11 43.7 3.2 0.00051 20.0 0.2 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ28952.1 - 1.2e-10 41.1 5.3 8.8e-07 28.7 0.2 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ28952.1 - 1.6e-09 38.1 7.0 3.3e-07 30.8 0.1 3.3 3 1 0 4 4 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ28952.1 - 1.2e-08 34.8 0.5 0.038 14.6 0.1 4.1 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ28952.1 - 1.4e-08 33.9 4.0 0.0067 16.1 0.8 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ28952.1 - 1.5e-08 33.7 1.5 0.0099 15.6 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ28952.1 - 8.6e-07 29.2 2.5 0.001 19.3 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat SGT1 PF07093.6 CBZ28952.1 - 1.9e-06 26.5 0.5 3.2e-06 25.8 0.4 1.3 1 0 0 1 1 1 1 SGT1 protein TPR_9 PF13371.1 CBZ28952.1 - 6.8e-05 22.6 0.1 0.018 14.8 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ28952.1 - 0.00012 22.1 5.3 0.0086 16.1 3.7 2.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBZ28952.1 - 0.001 19.4 3.2 1.2 9.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ28952.1 - 0.012 15.5 1.8 13 5.7 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.7 CBZ28952.1 - 0.021 14.4 1.1 0.73 9.3 0.1 2.8 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 MIT PF04212.13 CBZ28952.1 - 0.026 14.4 3.2 0.43 10.4 0.4 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain YjcQ PF09639.5 CBZ28952.1 - 0.084 12.9 0.1 0.28 11.3 0.1 2.0 1 1 0 1 1 1 0 YjcQ protein DSBA PF01323.15 CBZ28953.1 - 0.012 15.1 0.5 0.019 14.5 0.4 1.2 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Methyltransf_5 PF01795.14 CBZ28953.1 - 0.048 12.9 0.4 0.07 12.4 0.3 1.2 1 0 0 1 1 1 0 MraW methylase family TMA7 PF09072.5 CBZ28954.1 - 7.7e-20 71.1 14.7 8.3e-20 71.0 10.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 TFIIS_M PF07500.9 CBZ28954.1 - 0.17 11.9 4.2 0.18 11.8 2.9 1.1 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain PTS_EIIC PF02378.13 CBZ28955.1 - 0.016 14.0 0.1 0.018 13.8 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC FixG_C PF11614.3 CBZ28955.1 - 0.064 13.3 0.1 0.099 12.7 0.1 1.4 1 1 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Sod_Fe_C PF02777.13 CBZ28956.1 - 6.3e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBZ28956.1 - 2.1e-06 27.8 0.1 3.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain CATSPERG PF15064.1 CBZ28956.1 - 0.066 10.9 0.0 0.098 10.3 0.0 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit gamma zf-CCCH PF00642.19 CBZ28957.1 - 1.8e-06 27.4 2.4 1.8e-06 27.4 1.7 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ28957.1 - 0.061 13.3 1.7 0.13 12.3 1.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type DUF872 PF05915.7 CBZ28958.1 - 1.6e-08 34.4 0.2 2.4e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Claudin_2 PF13903.1 CBZ28958.1 - 0.015 14.9 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction FKBP_N PF01346.13 CBZ28958.1 - 0.18 11.8 0.4 0.27 11.2 0.3 1.1 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase P22_CoatProtein PF11651.3 CBZ28959.1 - 0.061 11.9 0.0 0.088 11.3 0.0 1.1 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 Cpn60_TCP1 PF00118.19 CBZ28961.1 - 4.8e-108 361.8 0.6 5.5e-108 361.6 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RabGAP-TBC PF00566.13 CBZ28963.1 - 1.1e-34 119.7 1.6 3.4e-34 118.1 1.1 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF4597 PF15366.1 CBZ28966.1 - 0.0037 16.8 1.6 0.0097 15.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4597) PPR_3 PF13812.1 CBZ28967.1 - 6.7e-08 32.2 8.2 0.14 12.4 0.1 7.0 6 0 0 6 6 6 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 CBZ28967.1 - 4.9e-05 23.2 0.0 18 5.3 0.0 5.4 5 1 0 5 5 5 1 PPR repeat family Apc3 PF12895.2 CBZ28967.1 - 7.4e-05 22.8 3.3 2.2 8.4 0.0 4.1 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 CBZ28967.1 - 0.0004 20.1 0.2 16 5.7 0.0 5.8 7 0 0 7 7 7 1 PPR repeat TPR_7 PF13176.1 CBZ28967.1 - 0.048 13.4 8.5 1e+02 3.0 0.0 6.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ28967.1 - 1.2 9.9 21.0 35 5.3 0.0 7.4 6 2 2 8 8 8 0 Tetratricopeptide repeat Aldedh PF00171.17 CBZ28969.1 - 4e-120 401.2 0.1 5.2e-120 400.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CBZ28969.1 - 0.019 14.2 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Pkinase PF00069.20 CBZ28970.1 - 3.2e-53 180.5 0.0 4e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28970.1 - 1.8e-18 66.5 0.0 2.5e-18 66.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ28970.1 - 1.1e-05 24.6 0.1 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ28970.1 - 0.00042 20.1 0.1 0.00063 19.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ28970.1 - 0.0015 17.5 0.0 0.0036 16.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CBZ28970.1 - 0.045 13.0 0.1 0.098 11.9 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Enterotoxin_a PF01375.12 CBZ28971.1 - 0.11 11.7 1.8 0.35 10.1 1.4 1.6 2 0 0 2 2 2 0 Heat-labile enterotoxin alpha chain PI-PLC-X PF00388.14 CBZ28974.1 - 3.4e-58 195.2 0.0 6.8e-58 194.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBZ28974.1 - 7.1e-34 116.3 0.0 1.2e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 CBZ28974.1 - 7.5e-17 60.9 0.1 2.8e-16 59.1 0.1 2.1 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.1 CBZ28974.1 - 2.5e-10 40.3 0.2 1.5e-06 28.2 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ28974.1 - 9.5e-10 37.0 0.1 0.013 14.7 0.0 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CBZ28974.1 - 7.8e-08 31.8 5.2 1.7e-06 27.5 0.7 3.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 CBZ28974.1 - 4.4e-07 28.9 2.1 0.002 17.3 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBZ28974.1 - 2.7e-06 26.7 0.1 0.14 12.0 0.1 3.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 CBZ28974.1 - 1e-05 25.0 0.1 2.1e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 EF hand GDPD PF03009.12 CBZ28974.1 - 0.0067 15.9 0.3 0.016 14.7 0.1 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family ATG13 PF10033.4 CBZ28974.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 13 EF-hand_4 PF12763.2 CBZ28974.1 - 0.061 13.0 0.5 2 8.1 0.4 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand zf-CHCC PF10276.4 CBZ28975.1 - 6.6e-05 22.6 1.8 6.6e-05 22.6 1.2 2.0 2 0 0 2 2 2 1 Zinc-finger domain Gp_dh_C PF02800.15 CBZ28976.1 - 3.2e-66 221.6 0.1 5.2e-66 220.9 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CBZ28976.1 - 2.1e-54 183.5 1.0 3.3e-54 182.9 0.7 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CBZ28976.1 - 0.0016 18.3 0.4 0.0048 16.7 0.3 2.0 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 CBZ28976.1 - 0.019 15.4 0.1 0.038 14.4 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2817 PF10994.3 CBZ28977.1 - 2.6e-103 345.7 0.0 3e-103 345.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.9 CBZ28977.1 - 6.7e-05 21.9 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Peptidase_M14 PF00246.19 CBZ28977.1 - 0.029 13.9 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 Zinc carboxypeptidase TPR_1 PF00515.23 CBZ28979.1 - 3.1e-103 333.5 32.4 1.4e-08 34.0 0.4 14.8 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ28979.1 - 1e-98 323.0 44.9 1.3e-15 56.8 3.0 9.2 7 2 1 9 9 9 8 TPR repeat TPR_2 PF07719.12 CBZ28979.1 - 5.2e-84 269.5 50.5 1.4e-06 27.7 0.6 15.3 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ28979.1 - 9.2e-53 172.1 15.5 2.7e-05 23.6 0.1 14.9 13 1 2 15 15 15 10 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ28979.1 - 2.4e-48 161.8 49.9 2.6e-08 34.3 0.6 9.7 7 3 3 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ28979.1 - 5e-44 144.8 27.3 6.4e-05 22.8 0.0 12.5 13 0 0 13 13 12 9 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ28979.1 - 6.7e-41 138.0 42.5 6.9e-05 22.6 0.0 11.6 3 2 8 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ28979.1 - 8.8e-40 134.5 45.4 6e-08 32.5 3.0 9.5 4 2 7 11 11 11 10 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ28979.1 - 1.1e-25 87.7 43.7 0.04 14.5 0.0 14.7 3 2 12 15 15 15 10 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ28979.1 - 2.4e-23 80.0 29.7 0.022 14.5 0.0 13.5 12 1 1 13 13 13 6 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ28979.1 - 5.3e-22 76.7 33.6 0.27 11.7 0.0 14.1 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ28979.1 - 7.2e-15 55.0 31.2 0.0001 22.5 0.9 8.9 5 2 4 10 10 9 4 Tetratricopeptide repeat Apc3 PF12895.2 CBZ28979.1 - 1.1e-12 47.8 31.9 4.1e-05 23.6 0.3 7.4 3 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.4 CBZ28979.1 - 1.7e-06 27.1 24.1 3.4 6.9 0.0 11.2 13 0 0 13 13 13 1 SHNi-TPR NARP1 PF12569.3 CBZ28979.1 - 0.00013 20.8 9.9 0.041 12.6 0.0 4.7 2 1 2 5 5 5 2 NMDA receptor-regulated protein 1 DUF3856 PF12968.2 CBZ28979.1 - 0.0012 18.7 12.2 16 5.3 0.1 7.7 5 2 2 7 7 7 0 Domain of Unknown Function (DUF3856) MIT PF04212.13 CBZ28979.1 - 0.0021 17.8 32.4 0.52 10.2 0.0 9.4 9 2 2 11 11 11 2 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.9 CBZ28979.1 - 0.0026 17.0 0.6 3.4 6.7 0.0 3.8 4 1 0 4 4 4 1 Coatomer epsilon subunit TPR_10 PF13374.1 CBZ28979.1 - 0.012 15.5 35.6 2.4 8.1 0.0 9.3 10 0 0 10 10 9 0 Tetratricopeptide repeat BTAD PF03704.12 CBZ28979.1 - 0.28 11.4 26.0 2.5 8.4 0.0 6.6 5 3 2 7 7 7 0 Bacterial transcriptional activator domain TPR_4 PF07721.9 CBZ28979.1 - 4.7 7.9 22.4 3.7 8.2 1.0 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat LSM PF01423.17 CBZ28980.1 - 4.8e-07 29.2 0.1 7e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBZ28980.1 - 0.044 13.7 0.1 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain NHL PF01436.16 CBZ28980.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 NHL repeat KH_1 PF00013.24 CBZ28981.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.6 1 1 0 1 1 1 0 KH domain KH_3 PF13014.1 CBZ28981.1 - 0.016 14.8 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 KH domain DUF1513 PF07433.6 CBZ28982.1 - 0.065 12.1 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) DUF21 PF01595.15 CBZ28983.1 - 2.4e-24 85.6 4.0 5.1e-24 84.5 2.8 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CBZ28983.1 - 2.4e-06 27.2 0.0 0.0036 17.0 0.0 2.7 2 0 0 2 2 2 2 CBS domain U-box PF04564.10 CBZ28983.1 - 0.11 12.4 0.0 2.6 8.0 0.0 2.8 3 0 0 3 3 3 0 U-box domain eIF-3_zeta PF05091.7 CBZ28984.1 - 2.9e-121 405.6 0.0 3.2e-121 405.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.20 CBZ28985.1 - 1.9e-66 223.8 0.0 2.8e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ28985.1 - 2.6e-45 154.5 0.0 4e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ28985.1 - 0.0017 17.3 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kinesin PF00225.18 CBZ28986.1 - 2.2e-81 273.1 0.0 2.2e-81 273.1 0.0 2.9 3 0 0 3 3 3 1 Kinesin motor domain tRNA_m1G_MT PF01746.16 CBZ28987.1 - 7.5e-24 84.3 0.0 1.3e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase GHMP_kinases_N PF00288.21 CBZ28988.1 - 4.1e-09 36.3 1.4 9.2e-09 35.2 0.9 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBZ28988.1 - 2.9e-07 30.6 0.1 8.1e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DUF2413 PF10310.4 CBZ28989.1 - 0.85 8.3 4.0 1.2 7.8 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PPR_3 PF13812.1 CBZ28990.1 - 0.016 15.4 1.3 27 5.3 0.0 5.1 5 0 0 5 5 5 0 Pentatricopeptide repeat domain MOZART2 PF12926.2 CBZ28990.1 - 0.031 13.8 0.1 0.34 10.5 0.0 2.7 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated SAM_decarbox PF01536.11 CBZ28991.1 - 6.1e-119 396.5 0.0 7.1e-119 396.3 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase SAM_decarbox PF01536.11 CBZ28992.1 - 9.9e-15 54.0 0.1 1.5e-09 36.9 0.1 2.0 1 1 1 2 2 2 2 Adenosylmethionine decarboxylase tRNA-synt_1 PF00133.17 CBZ28993.1 - 7.2e-193 641.8 0.0 3.3e-192 639.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CBZ28993.1 - 1e-37 129.2 0.0 1.8e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CBZ28993.1 - 1.1e-15 57.1 0.3 2e-07 30.0 0.1 3.8 4 1 0 4 4 4 3 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.4 CBZ28993.1 - 1.3e-15 57.1 0.8 3.1e-15 56.0 0.5 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.1 CBZ28993.1 - 6.4e-09 35.3 0.0 8.8e-05 21.8 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1d PF00750.14 CBZ28993.1 - 0.014 14.2 0.0 1.5 7.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (R) tRNA-synt_1b PF00579.20 CBZ28993.1 - 0.077 12.1 0.2 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) ADC PF06314.6 CBZ28993.1 - 0.082 12.2 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) tRNA-synt_1e PF01406.14 CBZ28993.1 - 0.091 11.8 0.4 2.3 7.2 0.1 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain MIS13 PF08202.6 CBZ28993.1 - 0.12 11.4 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Biotin_lipoyl_2 PF13533.1 CBZ28994.1 - 0.045 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Biotin-lipoyl like TRAP_beta PF05753.9 CBZ28995.1 - 4.5e-15 55.2 1.3 1.6e-14 53.5 0.9 1.8 1 1 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.13 CBZ28995.1 - 2.9e-07 30.4 1.8 3.7e-07 30.1 0.0 2.0 2 1 1 3 3 3 1 Domain of unknown function DUF11 CARDB PF07705.6 CBZ28995.1 - 7.8e-06 25.8 0.3 1.2e-05 25.3 0.2 1.3 1 0 0 1 1 1 1 CARDB Trichoplein PF13868.1 CBZ28997.1 - 1.6e-50 171.5 139.7 1.6e-50 171.5 96.8 1.8 1 1 0 2 2 2 1 Tumour suppressor, Mitostatin RRM_1 PF00076.17 CBZ28998.1 - 9.4e-09 34.7 0.0 1.4e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ28998.1 - 9.2e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ28998.1 - 1.3e-06 28.1 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG-CoA_red PF00368.13 CBZ28999.1 - 3.2e-153 509.8 3.7 3.8e-153 509.5 2.6 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Ribosomal_S26e PF01283.14 CBZ29000.1 - 2.3e-41 140.6 4.6 2.4e-41 140.5 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Viral_NABP PF05515.6 CBZ29000.1 - 0.17 12.1 0.2 0.17 12.1 0.1 1.5 2 0 0 2 2 2 0 Viral nucleic acid binding zf-CCHC_4 PF14392.1 CBZ29000.1 - 0.44 10.2 2.8 0.77 9.4 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle EMP24_GP25L PF01105.19 CBZ29001.1 - 5.9 6.5 8.7 0.44 10.2 0.6 2.7 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF4250 PF14056.1 CBZ29001.1 - 6 6.6 5.6 6.2 6.6 0.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4250) tRNA-synt_1c PF00749.16 CBZ29005.1 - 2.6e-99 331.8 0.1 3.5e-99 331.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CBZ29005.1 - 1.4e-35 122.4 0.1 3e-35 121.4 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF3832 PF12909.2 CBZ29005.1 - 0.0018 18.3 0.3 0.0074 16.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3832) Endonuc-dimeris PF09124.5 CBZ29005.1 - 0.066 12.8 0.3 0.27 10.8 0.1 2.2 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation Helicase_C PF00271.26 CBZ29006.1 - 4.6e-12 45.6 0.0 1.1e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 CBZ29006.1 - 1.3e-10 41.1 1.1 2.6e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.24 CBZ29006.1 - 1.9e-08 34.0 0.0 8.4e-08 31.8 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 CBZ29006.1 - 1.7e-05 24.6 0.0 4.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 CBZ29006.1 - 2.2e-05 24.5 1.2 0.00011 22.3 0.0 2.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 CBZ29006.1 - 0.022 13.6 6.3 0.05 12.5 4.3 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 CBZ29006.1 - 4.5 7.5 9.7 4.6 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.2 CBZ29007.1 - 3.5e-42 142.6 5.2 3.4e-20 72.1 0.1 4.2 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CBZ29007.1 - 8.1e-34 115.4 7.1 6.4e-10 39.2 0.0 6.3 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 CBZ29007.1 - 6.8e-33 110.8 12.6 3.3e-07 29.7 0.0 7.8 7 2 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 CBZ29007.1 - 1.9e-29 101.0 9.2 3.9e-11 42.8 0.3 7.1 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ29007.1 - 2.4e-27 92.2 1.2 5.7e-05 22.9 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat BTD PF09270.5 CBZ29007.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Beta-trefoil DNA-binding domain DUF3880 PF12996.2 CBZ29007.1 - 0.13 12.1 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) FlgN PF05130.7 CBZ29007.1 - 0.42 10.8 0.1 0.42 10.8 0.0 3.5 3 1 0 3 3 3 0 FlgN protein Metallophos PF00149.23 CBZ29009.1 - 7.2e-11 41.8 0.4 1.5e-10 40.8 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ubiquitin PF00240.18 CBZ29011.1 - 1.7e-13 49.7 0.0 3.5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 CBZ29011.1 - 1e-10 40.8 0.3 2.1e-10 39.9 0.2 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 CBZ29011.1 - 2.5e-08 33.5 1.7 1e-05 25.1 0.2 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 CBZ29011.1 - 6.4e-08 32.1 0.1 1.6e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 CBZ29011.1 - 0.0081 15.7 0.0 0.025 14.1 0.0 1.7 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain YukD PF08817.5 CBZ29011.1 - 0.018 15.6 0.0 0.049 14.2 0.0 1.8 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD MORN PF02493.15 CBZ29012.1 - 2.8e-93 300.3 105.4 5.3e-10 38.4 1.5 15.1 15 0 0 15 15 15 15 MORN repeat BAR PF03114.13 CBZ29013.1 - 0.00044 19.8 0.2 0.00058 19.4 0.1 1.2 1 0 0 1 1 1 1 BAR domain TMV_coat PF00721.16 CBZ29014.1 - 0.24 11.2 2.5 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Virus coat protein (TMV like) Ribosomal_L6 PF00347.18 CBZ29015.1 - 3.4e-28 97.9 3.4 7.3e-16 58.4 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Hormone_2 PF00123.15 CBZ29015.1 - 0.12 12.2 0.0 30 4.5 0.0 3.1 3 0 0 3 3 3 0 Peptide hormone EF-hand_7 PF13499.1 CBZ29017.1 - 4.4e-35 119.6 18.4 2e-08 34.2 0.0 6.7 6 1 1 7 7 7 6 EF-hand domain pair EF-hand_1 PF00036.27 CBZ29017.1 - 2.6e-34 113.9 11.5 2.2e-05 23.4 0.0 10.4 10 0 0 10 10 10 8 EF hand EF-hand_6 PF13405.1 CBZ29017.1 - 7.4e-31 103.2 15.0 0.00016 21.2 0.1 10.2 10 0 0 10 10 10 8 EF-hand domain EF-hand_5 PF13202.1 CBZ29017.1 - 3.3e-26 89.3 9.3 0.00045 19.4 0.0 8.4 8 0 0 8 8 8 7 EF hand EF-hand_8 PF13833.1 CBZ29017.1 - 6.3e-15 54.5 20.7 0.19 11.3 0.2 10.0 8 3 2 10 10 10 7 EF-hand domain pair SPARC_Ca_bdg PF10591.4 CBZ29017.1 - 3.2e-10 40.0 0.3 0.028 14.4 0.0 5.3 4 1 1 5 5 5 3 Secreted protein acidic and rich in cysteine Ca binding region Tropomyosin PF00261.15 CBZ29017.1 - 0.022 13.8 0.6 0.039 13.0 0.0 1.6 2 0 0 2 2 2 0 Tropomyosin PGK PF00162.14 CBZ29019.1 - 4.2e-137 456.7 0.2 5.4e-137 456.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase PAS PF00989.19 CBZ29019.1 - 6.6e-07 29.1 0.0 2.5e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 CBZ29019.1 - 1.1e-05 25.7 0.0 8.7e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 CBZ29019.1 - 0.00051 20.0 0.0 0.0024 17.9 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.1 CBZ29019.1 - 0.0071 16.1 0.0 0.027 14.3 0.0 2.0 1 0 0 1 1 1 1 PAS domain CAS_CSE1 PF03378.10 CBZ29020.1 - 3.7e-64 216.6 0.0 1.2e-63 214.8 0.0 1.9 2 1 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 CBZ29020.1 - 3.8e-49 167.2 0.0 5.9e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.7 CBZ29020.1 - 0.019 14.8 1.8 6.6 6.6 0.0 4.1 5 1 1 6 6 6 0 Exportin 1-like protein IBN_N PF03810.14 CBZ29020.1 - 0.048 13.5 0.0 0.19 11.6 0.0 2.1 1 0 0 1 1 1 0 Importin-beta N-terminal domain DUF3753 PF12575.3 CBZ29020.1 - 0.087 12.6 1.8 4.3 7.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) WD40 PF00400.27 CBZ29022.1 - 2.1e-06 27.3 12.0 0.041 13.7 1.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Dynein_heavy PF03028.10 CBZ29022.1 - 0.0034 15.4 0.0 0.0049 14.9 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Tcp11 PF05794.8 CBZ29023.1 - 8e-25 87.4 0.5 8e-25 87.4 0.3 1.9 2 0 0 2 2 2 1 T-complex protein 11 DUF2057 PF09829.4 CBZ29023.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) MKT1_C PF12246.3 CBZ29024.1 - 1.3e-28 99.6 0.0 1.8e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CBZ29024.1 - 4.2e-17 62.2 0.0 8.4e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication DNA_ligase_A_M PF01068.16 CBZ29025.1 - 1.4e-51 174.7 0.0 2.1e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CBZ29025.1 - 6e-40 136.9 0.0 8.7e-40 136.4 0.0 1.2 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CBZ29025.1 - 1.6e-24 86.1 0.0 4.2e-24 84.7 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CBZ29025.1 - 0.079 12.6 1.0 0.68 9.6 0.0 2.4 2 0 0 2 2 2 0 DNA ligase OB-like domain TPR_11 PF13414.1 CBZ29027.1 - 1.5e-12 46.9 10.4 0.00017 21.1 0.1 4.5 3 1 1 5 5 5 4 TPR repeat TPR_16 PF13432.1 CBZ29027.1 - 5.7e-10 39.5 10.1 2.3e-05 24.9 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ29027.1 - 4.4e-06 26.4 1.2 4.8 7.6 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ29027.1 - 9.1e-05 22.7 11.1 0.054 14.1 0.0 4.7 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ29027.1 - 0.00027 20.4 2.4 4.5 7.0 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ29027.1 - 0.0039 17.0 6.7 0.054 13.3 0.5 3.2 2 1 0 2 2 2 1 Tetratricopeptide repeat SPO22 PF08631.5 CBZ29027.1 - 0.021 13.9 0.0 3.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.12 CBZ29027.1 - 0.023 14.5 0.0 0.023 14.5 0.0 5.0 7 0 0 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ29027.1 - 0.15 12.2 0.9 0.44 10.7 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CBZ29027.1 - 0.2 11.5 4.1 0.92 9.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ29027.1 - 0.37 11.1 8.1 0.76 10.1 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Yippee-Mis18 PF03226.9 CBZ29028.1 - 2.1e-14 53.3 0.4 2.6e-14 53.0 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly C1_4 PF07975.7 CBZ29028.1 - 0.1 12.6 0.8 13 5.8 0.1 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain zf-ribbon_3 PF13248.1 CBZ29028.1 - 0.13 11.4 2.0 5 6.4 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.20 CBZ29029.1 - 1.1e-30 106.6 0.0 1.5e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29029.1 - 1.7e-12 46.9 0.0 2.1e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ29029.1 - 0.022 14.5 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ29029.1 - 0.095 11.6 0.0 0.19 10.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf-MIZ PF02891.15 CBZ29031.1 - 5.6e-18 64.1 6.1 9e-18 63.5 4.2 1.3 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CBZ29031.1 - 8.3e-06 25.2 2.3 1.6e-05 24.2 1.6 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.7 CBZ29031.1 - 0.13 11.4 0.5 0.18 10.9 0.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-RING_2 PF13639.1 CBZ29031.1 - 0.43 10.4 6.2 1.8 8.4 4.0 2.1 2 0 0 2 2 2 0 Ring finger domain S-AdoMet_synt_C PF02773.11 CBZ29032.1 - 4.6e-70 233.7 0.2 7.7e-70 232.9 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CBZ29032.1 - 1.3e-45 154.2 0.0 2.3e-44 150.1 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CBZ29032.1 - 1.7e-39 134.0 0.2 3.2e-39 133.1 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Strep_pep PF14404.1 CBZ29032.1 - 0.033 14.3 0.0 0.081 13.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species Rhodanese PF00581.15 CBZ29033.1 - 1.7e-05 25.0 0.0 2.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain RF-1 PF00472.15 CBZ29034.1 - 1.7e-11 43.8 0.1 6.4e-11 42.0 0.0 2.0 2 0 0 2 2 2 1 RF-1 domain Caldesmon PF02029.10 CBZ29034.1 - 0.001 17.5 0.1 0.001 17.5 0.1 1.5 2 0 0 2 2 2 1 Caldesmon CARD PF00619.16 CBZ29034.1 - 0.074 12.8 0.1 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 Caspase recruitment domain p450 PF00067.17 CBZ29035.1 - 2e-45 155.2 0.1 2.7e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mago_nashi PF02792.9 CBZ29036.1 - 2.2e-54 183.0 0.2 2.6e-54 182.8 0.1 1.0 1 0 0 1 1 1 1 Mago nashi protein zf-CCCH PF00642.19 CBZ29037.1 - 6.1e-06 25.7 2.4 1.5e-05 24.5 1.7 1.7 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 CBZ29038.1 - 8.4e-37 126.7 0.1 3.8e-17 62.3 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29038.1 - 6.5e-10 38.5 0.0 1.1e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase VIT1 PF01988.14 CBZ29038.1 - 0.12 11.8 0.2 0.31 10.4 0.2 1.7 1 0 0 1 1 1 0 VIT family Ribosomal_S11 PF00411.14 CBZ29039.1 - 7.6e-41 138.7 0.7 9.3e-41 138.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF814 PF05670.8 CBZ29039.1 - 0.08 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF814) ATP-synt_DE_N PF02823.11 CBZ29040.1 - 1.6e-16 59.7 0.0 3.1e-16 58.8 0.0 1.5 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.15 CBZ29040.1 - 0.43 10.5 3.7 0.61 10.0 2.5 1.2 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF773 PF05600.7 CBZ29041.1 - 2.2e-14 53.1 11.8 1.4e-07 30.7 2.5 3.6 1 1 2 3 3 3 3 Protein of unknown function (DUF773) Chordopox_A30L PF06015.7 CBZ29041.1 - 0.041 13.4 0.1 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus A30L protein Prefoldin_2 PF01920.15 CBZ29041.1 - 0.1 12.3 4.3 4.2 7.1 0.3 2.5 2 0 0 2 2 2 0 Prefoldin subunit EzrA PF06160.7 CBZ29041.1 - 0.67 8.0 7.8 0.72 7.9 0.8 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DivIC PF04977.10 CBZ29041.1 - 1.1 8.7 5.3 1 8.9 1.0 2.4 2 0 0 2 2 2 0 Septum formation initiator FlgN PF05130.7 CBZ29041.1 - 4.2 7.6 8.1 2.6 8.2 1.0 2.4 2 1 0 2 2 2 0 FlgN protein Nup54 PF13874.1 CBZ29041.1 - 5.4 6.6 8.2 4 7.1 0.7 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Cyclin PF08613.6 CBZ29043.1 - 9.9e-20 71.4 0.0 1.5e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBZ29043.1 - 1.1e-06 28.2 0.1 1.8e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain LRR_4 PF12799.2 CBZ29044.1 - 5.1e-18 64.2 9.9 2.7e-05 23.6 2.3 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ29044.1 - 1.9e-10 40.3 13.6 2.1e-07 30.5 3.0 3.1 1 1 2 3 3 3 3 Leucine rich repeat LRR_9 PF14580.1 CBZ29044.1 - 1.3e-09 37.8 0.5 1.5e-06 27.9 0.0 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.28 CBZ29044.1 - 0.00028 20.4 8.5 2.2 8.6 0.0 5.3 2 1 1 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ29044.1 - 0.00098 18.9 9.2 6.7 7.3 0.2 5.9 4 1 1 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 CBZ29044.1 - 0.0019 18.0 10.0 0.18 11.9 0.0 4.9 2 1 3 5 5 5 2 Leucine Rich repeat Ribosomal_L15e PF00827.12 CBZ29045.1 - 6.8e-90 299.7 9.1 7.7e-90 299.5 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 ATP-synt_C PF00137.16 CBZ29046.1 - 2.8e-27 94.3 39.5 1.6e-15 56.6 7.7 2.7 3 0 0 3 3 3 2 ATP synthase subunit C SnoaL_2 PF12680.2 CBZ29047.1 - 9.8e-06 25.9 0.1 1.3e-05 25.4 0.1 1.6 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 CBZ29047.1 - 0.00025 21.0 0.2 0.00075 19.5 0.1 1.8 2 1 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.7 CBZ29047.1 - 0.0029 17.1 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.1 CBZ29047.1 - 0.0088 16.2 0.0 0.02 15.1 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4440) DUF4572 PF15139.1 CBZ29048.1 - 0.022 14.5 0.8 0.29 10.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4572) AAA_33 PF13671.1 CBZ29048.1 - 0.14 12.0 4.1 0.13 12.1 1.3 2.2 1 1 0 1 1 1 0 AAA domain DUF3808 PF10300.4 CBZ29049.1 - 1.2e-27 96.6 4.4 5.7e-27 94.4 2.7 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 CBZ29049.1 - 1.2e-13 50.7 0.4 1.3e-05 25.0 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ29049.1 - 2.7e-08 33.3 10.3 0.0046 16.5 0.0 4.3 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 CBZ29049.1 - 5.1e-08 32.2 4.2 0.14 12.1 0.0 5.1 6 0 0 6 6 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ29049.1 - 1.4e-07 31.5 2.0 0.0041 17.2 0.3 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBZ29049.1 - 7e-05 23.0 1.3 2 8.8 0.1 5.1 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ29049.1 - 0.00011 22.7 1.6 0.59 10.8 1.0 4.8 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ29049.1 - 0.00056 20.3 2.9 4.2 8.2 0.1 5.1 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ29049.1 - 0.00069 19.1 0.3 10 5.9 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ29049.1 - 0.0023 18.2 3.5 2.1 9.0 0.2 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ29049.1 - 0.0042 16.7 8.5 7.5 6.5 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF2225 PF09986.4 CBZ29049.1 - 0.084 12.3 4.4 0.29 10.5 0.8 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 CBZ29049.1 - 2.7 8.0 5.3 72 3.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat IncA PF04156.9 CBZ29050.1 - 0.046 13.3 0.0 0.046 13.3 0.0 2.3 3 0 0 3 3 3 0 IncA protein CPSF_A PF03178.10 CBZ29051.1 - 7.2e-61 206.0 0.0 1.3e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 CBZ29051.1 - 0.00036 18.8 0.0 0.00059 18.0 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_60s PF00428.14 CBZ29052.1 - 5.5e-25 87.5 9.7 6.8e-25 87.2 6.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PepSY_2 PF13670.1 CBZ29052.1 - 0.022 14.6 4.8 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Ribosomal_60s PF00428.14 CBZ29053.1 - 2.8e-25 88.5 10.8 3.3e-25 88.2 7.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PepSY_2 PF13670.1 CBZ29053.1 - 0.087 12.7 6.5 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain YopE_N PF09020.5 CBZ29054.1 - 0.069 13.1 0.4 0.12 12.4 0.0 1.6 2 0 0 2 2 2 0 YopE, N terminal Fer4_17 PF13534.1 CBZ29054.1 - 2.8 8.3 7.3 15 6.0 1.3 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Meth_synt_2 PF01717.13 CBZ29055.1 - 5e-146 485.7 0.0 1.1e-138 461.6 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CBZ29055.1 - 8e-127 422.7 0.0 5.2e-110 367.5 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain MIP PF00230.15 CBZ29056.1 - 4.1e-47 160.5 12.6 5.2e-47 160.1 8.8 1.0 1 0 0 1 1 1 1 Major intrinsic protein Zip PF02535.17 CBZ29056.1 - 0.38 9.6 4.3 1.5 7.7 3.0 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter RINGv PF12906.2 CBZ29057.1 - 9.2e-12 44.8 5.2 9.2e-12 44.8 3.6 1.9 2 0 0 2 2 2 1 RING-variant domain BT1 PF03092.11 CBZ29058.1 - 3.2e-07 29.4 21.3 1.2e-06 27.4 14.8 1.7 1 1 0 1 1 1 1 BT1 family MFS_2 PF13347.1 CBZ29058.1 - 2e-05 23.2 19.3 2e-05 23.2 13.4 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein Pro_isomerase PF00160.16 CBZ29059.1 - 7.5e-44 149.6 0.0 9.4e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ResIII PF04851.10 CBZ29061.1 - 5.5e-13 49.1 0.0 3.7e-12 46.4 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T5orf172 PF10544.4 CBZ29061.1 - 1.2e-08 35.2 0.0 3.5e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain DEAD PF00270.24 CBZ29061.1 - 2.4e-08 33.6 0.0 4.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ29061.1 - 9.1e-05 22.2 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBZ29061.1 - 0.00064 18.6 0.0 0.0066 15.2 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain MUG113 PF13455.1 CBZ29061.1 - 0.014 15.8 0.0 0.047 14.1 0.0 1.9 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 DUF3505 PF12013.3 CBZ29061.1 - 0.03 14.5 0.6 0.03 14.5 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3505) zf-CCCH PF00642.19 CBZ29062.1 - 0.00044 19.8 12.8 0.0022 17.6 2.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ29062.1 - 0.12 12.3 10.9 0.74 9.9 3.5 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Peptidase_C33 PF05412.7 CBZ29063.1 - 0.08 12.7 0.0 0.47 10.2 0.0 2.2 2 1 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase cNMP_binding PF00027.24 CBZ29063.1 - 0.081 12.7 0.0 0.82 9.5 0.0 2.4 1 1 0 1 1 1 0 Cyclic nucleotide-binding domain Peptidase_M22 PF00814.20 CBZ29064.1 - 2.4e-86 289.5 0.0 3e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family FG-GAP PF01839.18 CBZ29065.1 - 4.5e-14 51.6 22.3 0.013 15.1 0.0 6.6 6 0 0 6 6 6 5 FG-GAP repeat VCBS PF13517.1 CBZ29065.1 - 1.4e-12 47.7 18.3 9.7e-05 22.6 2.9 6.8 6 1 1 7 7 7 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ_2 PF13360.1 CBZ29065.1 - 0.00042 19.8 0.4 0.55 9.6 0.0 3.2 2 1 0 3 3 3 1 PQQ-like domain BBS2_C PF14782.1 CBZ29065.1 - 0.0032 16.0 0.1 2.4 6.6 0.0 3.0 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, C-terminal TcdB_toxin_midN PF12256.3 CBZ29065.1 - 0.023 14.1 7.3 0.75 9.2 0.4 3.9 3 1 1 4 4 4 0 Insecticide toxin TcdB middle/N-terminal region BBS2_Mid PF14783.1 CBZ29065.1 - 0.19 11.4 0.5 88 2.9 0.0 3.8 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Reo_sigmaC PF04582.7 CBZ29067.1 - 1.4 7.9 13.0 1 8.5 0.8 3.6 2 1 2 4 4 4 0 Reovirus sigma C capsid protein UCH PF00443.24 CBZ29068.1 - 1.7e-43 148.6 0.0 2.5e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ29068.1 - 2.1e-17 63.5 0.0 3.1e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CBZ29068.1 - 2.2e-08 33.3 0.0 6.1e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 CBZ29068.1 - 0.029 14.6 0.1 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain UPF0262 PF06793.7 CBZ29069.1 - 0.035 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Flagellar_rod PF05149.7 CBZ29069.1 - 0.12 11.5 0.3 0.22 10.6 0.2 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein CybS PF05328.7 CBZ29069.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 CybS CytoC_RC PF02276.13 CBZ29069.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit RNA_pol_Rpb2_6 PF00562.23 CBZ29070.1 - 2.2e-117 392.0 0.0 2.9e-117 391.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CBZ29070.1 - 5.3e-40 136.5 0.0 8e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 CBZ29070.1 - 1.8e-28 98.6 0.0 1.1e-27 96.0 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 CBZ29070.1 - 5.7e-24 84.5 0.0 9.6e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 CBZ29070.1 - 1.2e-22 79.5 1.9 2.4e-22 78.4 1.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CBZ29070.1 - 9.5e-20 70.1 1.3 1.6e-19 69.4 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CBZ29070.1 - 6e-09 35.7 0.6 1.2e-08 34.7 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 HisKA_2 PF07568.7 CBZ29071.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase Trp_repressor PF01371.14 CBZ29072.1 - 0.095 12.6 0.0 0.49 10.3 0.0 2.0 2 0 0 2 2 2 0 Trp repressor protein Glyco_transf_21 PF13506.1 CBZ29072.1 - 0.13 11.5 0.9 0.25 10.6 0.2 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 21 Nol1_Nop2_Fmu PF01189.12 CBZ29073.1 - 6e-84 281.7 0.0 1.1e-83 280.9 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CBZ29073.1 - 3.8e-05 23.6 0.0 0.00011 22.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CBZ29073.1 - 0.00029 20.8 0.0 0.00071 19.6 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 CBZ29073.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ29073.1 - 0.0097 16.4 0.8 0.038 14.5 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.14 CBZ29073.1 - 0.024 14.1 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) WD40 PF00400.27 CBZ29074.1 - 2.3e-33 112.8 7.8 1.9e-07 30.6 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat NLE PF08154.7 CBZ29074.1 - 4.2e-13 49.0 0.6 7.3e-13 48.3 0.4 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Lactonase PF10282.4 CBZ29074.1 - 0.044 12.8 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Daxx PF03344.10 CBZ29076.1 - 0.011 14.2 16.1 0.011 14.2 11.2 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 CBZ29076.1 - 0.042 13.1 16.2 0.052 12.8 11.2 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 CBZ29076.1 - 0.066 11.1 20.3 0.073 10.9 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family CSTF2_hinge PF14327.1 CBZ29076.1 - 0.083 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 SAPS PF04499.10 CBZ29076.1 - 0.47 9.0 4.3 0.53 8.8 3.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Osteopontin PF00865.13 CBZ29076.1 - 0.7 9.0 25.0 0.95 8.6 17.4 1.1 1 0 0 1 1 1 0 Osteopontin CDC45 PF02724.9 CBZ29076.1 - 0.77 7.7 13.5 0.92 7.4 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 CBZ29076.1 - 1.5 7.1 16.1 1.8 6.8 11.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ebola_NP PF05505.7 CBZ29076.1 - 2.4 6.1 10.1 2.7 5.9 7.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein BUD22 PF09073.5 CBZ29076.1 - 4.3 6.3 20.3 5.7 5.8 14.1 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 CBZ29078.1 - 0.0056 15.2 16.2 0.0061 15.1 11.2 1.0 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 CBZ29078.1 - 0.098 10.5 20.9 0.11 10.4 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family CSTF2_hinge PF14327.1 CBZ29078.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 SDA1 PF05285.7 CBZ29078.1 - 0.15 11.2 17.7 0.19 10.9 12.3 1.2 1 0 0 1 1 1 0 SDA1 Osteopontin PF00865.13 CBZ29078.1 - 0.46 9.6 24.3 0.61 9.2 16.8 1.2 1 0 0 1 1 1 0 Osteopontin CDC45 PF02724.9 CBZ29078.1 - 0.65 7.9 13.0 0.8 7.6 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.10 CBZ29078.1 - 0.8 8.2 4.9 0.88 8.1 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.7 CBZ29078.1 - 1.3 7.3 15.7 1.6 7.0 10.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.5 CBZ29078.1 - 4.6 6.2 20.4 6 5.8 14.1 1.1 1 0 0 1 1 1 0 BUD22 Reo_sigmaC PF04582.7 CBZ29079.1 - 0.032 13.4 33.9 1.2 8.2 0.1 6.9 1 1 5 7 7 7 0 Reovirus sigma C capsid protein Cupin_4 PF08007.7 CBZ29080.1 - 1.8e-40 139.1 0.5 1.3e-39 136.3 0.4 2.0 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 CBZ29080.1 - 2.9e-08 33.5 0.1 1e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Cupin-like domain 2OG-FeII_Oxy PF03171.15 CBZ29080.1 - 0.0037 17.5 0.3 0.16 12.3 0.0 2.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.6 CBZ29080.1 - 0.051 13.0 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Helicase_C PF00271.26 CBZ29081.1 - 5.1e-09 35.8 0.0 1.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ29081.1 - 3e-07 30.0 0.0 7.1e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.18 CBZ29081.1 - 0.0037 17.2 0.0 0.014 15.3 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) 2OG-FeII_Oxy_3 PF13640.1 CBZ29084.1 - 1e-05 25.9 0.1 1.8e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tet_JBP PF12851.2 CBZ29084.1 - 0.014 14.6 0.2 0.028 13.6 0.0 1.5 2 0 0 2 2 2 0 Oxygenase domain of the 2OGFeDO superfamily COPIIcoated_ERV PF07970.7 CBZ29085.1 - 4.1e-21 75.6 0.0 6.1e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CBZ29085.1 - 2e-06 27.6 0.0 4.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Kinesin PF00225.18 CBZ29086.1 - 3.1e-88 295.6 0.3 5.8e-88 294.7 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain DUF3972 PF13118.1 CBZ29086.1 - 0.036 14.1 0.3 0.075 13.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Tombus_P33 PF08500.5 CBZ29086.1 - 0.051 13.3 0.1 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Tombusvirus p33 Med30 PF11315.3 CBZ29086.1 - 0.17 11.9 1.8 0.73 9.9 0.7 2.2 2 0 0 2 2 2 0 Mediator complex subunit 30 TMF_DNA_bd PF12329.3 CBZ29086.1 - 2.8 7.8 8.8 0.28 11.0 2.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CRAL_TRIO PF00650.15 CBZ29087.1 - 8.9e-14 51.2 0.1 2.3e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain IncA PF04156.9 CBZ29087.1 - 0.0057 16.2 0.6 0.0057 16.2 0.4 3.7 2 1 0 3 3 3 1 IncA protein Abhydrolase_6 PF12697.2 CBZ29087.1 - 0.0095 15.8 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family CRAL_TRIO PF00650.15 CBZ29088.1 - 3.2e-14 52.7 0.0 5e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Aa_trans PF01490.13 CBZ29089.1 - 6.6e-30 103.9 16.9 7.4e-30 103.7 11.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 CBZ29090.1 - 7.2e-54 182.8 33.0 8.9e-54 182.5 22.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3082 PF11282.3 CBZ29090.1 - 6.3 6.9 12.9 0.59 10.2 1.4 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3082) Aa_trans PF01490.13 CBZ29091.1 - 7.2e-54 182.8 33.0 8.9e-54 182.5 22.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3082 PF11282.3 CBZ29091.1 - 6.3 6.9 12.9 0.59 10.2 1.4 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3082) Aa_trans PF01490.13 CBZ29092.1 - 2.8e-49 167.6 38.2 3.4e-49 167.4 26.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CBZ29092.1 - 2.4e-09 36.2 22.4 2.4e-09 36.2 15.5 2.0 2 0 0 2 2 2 1 Amino acid permease Trp_Tyr_perm PF03222.8 CBZ29092.1 - 2.3e-05 23.4 17.9 2.3e-05 23.4 12.4 2.1 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family CRAL_TRIO PF00650.15 CBZ29093.1 - 4.8e-13 48.8 0.0 7.6e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Syd PF07348.7 CBZ29093.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Syd protein (SUKH-2) NHase_beta PF02211.10 CBZ29094.1 - 0.15 11.7 1.8 0.14 11.8 0.3 1.6 2 0 0 2 2 2 0 Nitrile hydratase beta subunit Peptidase_C2 PF00648.16 CBZ29096.1 - 2.8e-39 134.8 0.0 4.1e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ29096.1 - 1.4e-26 92.4 0.0 2.6e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 CBZ29097.1 - 5.1e-24 84.7 0.0 8.9e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ29097.1 - 5.8e-17 61.5 0.1 2.2e-16 59.6 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) DUF1935 PF09149.5 CBZ29098.1 - 3.1e-17 62.4 0.0 6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 CBZ29098.1 - 2.2e-12 46.6 0.0 5.7e-12 45.2 0.0 1.7 1 1 0 1 1 1 1 Calpain family cysteine protease Amastin PF07344.6 CBZ29099.1 - 1.3e-51 174.3 11.0 1.5e-51 174.0 7.6 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ29099.1 - 0.0007 19.3 8.3 0.0007 19.3 5.8 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBZ29100.1 - 3.7e-50 169.5 9.2 4.5e-50 169.2 6.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ29100.1 - 0.0031 17.2 8.0 0.0031 17.2 5.6 2.2 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction zf-DHHC PF01529.15 CBZ29100.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase DUF4525 PF15027.1 CBZ29100.1 - 0.79 9.2 2.9 8.4 5.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) Cytochrom_B_N PF00033.14 CBZ29100.1 - 3.3 7.0 8.6 6.3 6.1 2.5 2.2 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Amastin PF07344.6 CBZ29101.1 - 2.3e-54 183.1 7.0 2.8e-54 182.9 4.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ29101.1 - 0.00014 21.6 6.2 0.00014 21.6 4.3 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF4525 PF15027.1 CBZ29101.1 - 0.13 11.7 0.4 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) Cytochrom_B_N PF00033.14 CBZ29101.1 - 1.4 8.2 7.1 1.7 7.9 1.6 2.3 2 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF975 PF06161.6 CBZ29101.1 - 1.9 8.1 5.8 0.18 11.5 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF975) Peptidase_C2 PF00648.16 CBZ29102.1 - 1.4e-56 191.6 0.0 1.9e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ29102.1 - 1.9e-21 75.9 0.2 3.6e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) AAA_14 PF13173.1 CBZ29103.1 - 0.022 14.6 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBZ29103.1 - 0.025 14.5 0.1 0.047 13.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain cNMP_binding PF00027.24 CBZ29105.1 - 6.8e-20 70.6 0.1 0.00041 20.0 0.0 5.3 4 2 0 4 4 4 4 Cyclic nucleotide-binding domain DUF3606 PF12244.3 CBZ29105.1 - 0.16 11.5 1.3 3.9 7.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) DnaJ PF00226.26 CBZ29107.1 - 1.5e-22 79.1 0.3 2.7e-22 78.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.1 CBZ29107.1 - 0.0012 18.1 0.2 0.0023 17.2 0.1 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing TRM13 PF05206.9 CBZ29108.1 - 4e-62 209.7 0.0 4.6e-60 203.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 CBZ29108.1 - 5.2e-11 41.7 6.5 5.2e-11 41.7 4.5 2.2 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 CBZ29108.1 - 4.5e-10 39.0 0.8 9.1e-10 38.0 0.6 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 CBZ29108.1 - 0.007 16.0 0.9 0.028 14.0 0.6 2.0 1 1 0 1 1 1 1 Methyltransferase domain ABC_membrane_2 PF06472.10 CBZ29110.1 - 2.2e-79 266.5 5.8 2.2e-79 266.5 4.0 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CBZ29110.1 - 6e-15 55.7 0.0 1.1e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Med3 PF11593.3 CBZ29110.1 - 6.4 5.8 5.4 2.5 7.2 0.4 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal GHMP_kinases_N PF00288.21 CBZ29112.1 - 1.8e-16 59.9 0.3 4.3e-16 58.7 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CBZ29112.1 - 4.5e-16 58.8 0.3 8.9e-16 57.8 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Aa_trans PF01490.13 CBZ29113.1 - 1e-47 162.5 34.6 1.2e-47 162.3 24.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ29113.1 - 1.3e-11 43.9 12.3 1.3e-11 43.9 8.5 2.2 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 CBZ29114.1 - 1.5e-47 161.9 32.5 2e-47 161.6 22.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ29114.1 - 1.4e-07 30.6 13.3 1.4e-07 30.6 9.2 2.2 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 CBZ29115.1 - 2.9e-42 144.6 32.1 3.9e-42 144.1 22.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1145 PF06611.7 CBZ29115.1 - 8.7 6.0 9.2 16 5.2 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1145) FA_hydroxylase PF04116.8 CBZ29116.1 - 6.6e-10 39.3 15.5 9.3e-10 38.9 10.0 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SPC12 PF06645.8 CBZ29117.1 - 0.077 12.8 0.2 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) FlgN PF05130.7 CBZ29117.1 - 4.1 7.6 10.3 0.79 9.9 2.4 2.1 2 0 0 2 2 2 0 FlgN protein Ribosomal_L7Ae PF01248.21 CBZ29118.1 - 8.4e-05 22.0 0.0 0.00023 20.5 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Antimicrobial19 PF08225.6 CBZ29118.1 - 0.026 13.9 0.1 0.056 12.8 0.1 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide Histone_HNS PF00816.16 CBZ29118.1 - 0.04 14.4 0.4 0.15 12.6 0.1 2.1 2 0 0 2 2 2 0 H-NS histone family Secretin_N PF03958.12 CBZ29120.1 - 0.038 14.1 0.0 0.68 10.1 0.0 2.8 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain FtsJ PF01728.14 CBZ29122.1 - 3e-43 147.9 0.0 4.3e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase C2 PF00168.25 CBZ29125.1 - 3.1e-20 71.8 0.1 5.1e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.1 CBZ29125.1 - 0.074 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 CEP76 C2 domain Peptidase_M41 PF01434.13 CBZ29127.1 - 4.8e-52 176.5 0.0 1.1e-51 175.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBZ29127.1 - 4e-34 117.6 0.0 8.6e-34 116.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ29127.1 - 0.00017 21.6 0.3 0.19 11.9 0.1 2.9 1 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CBZ29127.1 - 0.00052 19.7 0.5 0.13 11.9 0.3 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ29127.1 - 0.0017 19.1 0.1 0.01 16.6 0.0 2.4 3 0 0 3 3 1 1 AAA domain AAA_2 PF07724.9 CBZ29127.1 - 0.0019 18.1 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CBZ29127.1 - 0.0064 16.2 1.4 0.029 14.1 1.0 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 CBZ29127.1 - 0.008 16.1 0.4 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CBZ29127.1 - 0.028 13.8 0.9 0.063 12.6 0.6 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 CBZ29127.1 - 0.033 14.1 0.4 0.14 12.1 0.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 CBZ29127.1 - 0.036 13.9 0.0 0.096 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 CBZ29127.1 - 0.039 12.9 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CBZ29127.1 - 0.062 13.6 0.1 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CBZ29127.1 - 0.096 11.8 0.3 0.19 10.8 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MFS_1 PF07690.11 CBZ29129.1 - 8e-09 34.6 28.0 8e-09 34.6 19.4 3.8 2 2 0 2 2 2 2 Major Facilitator Superfamily CesT PF05932.8 CBZ29131.1 - 9e-17 61.0 0.1 9.6e-16 57.7 0.0 2.4 2 0 0 2 2 2 1 Tir chaperone protein (CesT) family DivIC PF04977.10 CBZ29131.1 - 0.014 14.8 1.0 0.025 14.0 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF2543 PF10820.3 CBZ29132.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) DivIVA PF05103.8 CBZ29132.1 - 1.6 8.7 7.0 0.75 9.8 0.4 2.2 1 1 1 2 2 2 0 DivIVA protein HAUS6_N PF14661.1 CBZ29133.1 - 0.031 13.6 3.2 0.059 12.7 2.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus MutS_III PF05192.13 CBZ29133.1 - 0.039 13.7 3.0 0.058 13.1 2.1 1.4 1 1 0 1 1 1 0 MutS domain III DNA_Packaging PF11053.3 CBZ29133.1 - 0.093 12.3 0.4 0.17 11.4 0.3 1.4 1 0 0 1 1 1 0 Terminase DNA packaging enzyme TMF_DNA_bd PF12329.3 CBZ29133.1 - 0.17 11.7 4.8 0.38 10.5 3.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 CBZ29133.1 - 2.3 8.2 8.4 1.4 8.9 2.8 2.3 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PGBA_C PF15437.1 CBZ29134.1 - 3.3e-06 27.1 2.6 9.3e-06 25.6 1.8 1.7 1 0 0 1 1 1 1 Plasminogen-binding protein pgbA C-terminal HsbA PF12296.3 CBZ29134.1 - 0.0079 16.0 2.9 0.31 10.9 0.0 3.2 2 1 1 3 3 3 1 Hydrophobic surface binding protein A CotJB PF12652.2 CBZ29134.1 - 0.05 13.6 3.9 19 5.3 0.9 3.8 1 1 1 3 3 3 0 CotJB protein DUF479 PF04336.7 CBZ29134.1 - 0.054 13.6 3.3 0.27 11.3 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF479 Toxin_52 PF15605.1 CBZ29134.1 - 0.21 11.4 1.8 8.8 6.2 0.5 2.6 2 1 0 2 2 2 0 Putative toxin 52 DUF1932 PF09130.6 CBZ29134.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1932) AAA_23 PF13476.1 CBZ29134.1 - 0.33 11.2 2.8 0.54 10.5 1.9 1.3 1 0 0 1 1 1 0 AAA domain MutS_III PF05192.13 CBZ29135.1 - 0.0078 16.0 1.3 0.011 15.5 0.9 1.4 1 0 0 1 1 1 1 MutS domain III DNA_Packaging PF11053.3 CBZ29135.1 - 0.047 13.3 0.4 0.082 12.5 0.2 1.3 1 0 0 1 1 1 0 Terminase DNA packaging enzyme AKNA PF12443.3 CBZ29135.1 - 0.083 12.9 3.2 0.21 11.5 2.2 1.7 1 0 0 1 1 1 0 AT-hook-containing transcription factor HAUS6_N PF14661.1 CBZ29135.1 - 0.2 10.9 6.9 0.027 13.8 2.1 1.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Bacillus_HBL PF05791.6 CBZ29135.1 - 0.28 10.5 3.2 0.75 9.1 1.0 2.4 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TMF_DNA_bd PF12329.3 CBZ29135.1 - 0.47 10.2 7.2 0.21 11.4 3.3 1.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 CBZ29135.1 - 0.94 9.5 8.7 0.63 10.0 2.7 2.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 CBZ29135.1 - 1.3 8.7 10.5 1.5 8.6 6.9 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) C2 PF00168.25 CBZ29136.1 - 1.7e-17 63.0 0.0 2.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain C2 PF00168.25 CBZ29137.1 - 7.3e-21 73.8 0.3 9.7e-21 73.4 0.2 1.2 1 0 0 1 1 1 1 C2 domain PGBA_C PF15437.1 CBZ29142.1 - 3.4e-06 27.1 2.6 9.3e-06 25.6 1.8 1.7 1 0 0 1 1 1 1 Plasminogen-binding protein pgbA C-terminal HsbA PF12296.3 CBZ29142.1 - 0.008 16.0 2.9 0.31 10.9 0.0 3.2 2 1 2 4 4 4 1 Hydrophobic surface binding protein A CotJB PF12652.2 CBZ29142.1 - 0.052 13.6 4.0 14 5.8 0.5 3.8 1 1 2 4 4 4 0 CotJB protein DUF479 PF04336.7 CBZ29142.1 - 0.052 13.6 3.3 0.27 11.3 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF479 Toxin_52 PF15605.1 CBZ29142.1 - 0.17 11.7 1.4 8.8 6.2 0.5 2.5 2 0 0 2 2 2 0 Putative toxin 52 AAA_23 PF13476.1 CBZ29142.1 - 0.33 11.2 2.8 0.54 10.5 1.9 1.3 1 0 0 1 1 1 0 AAA domain DUF1932 PF09130.6 CBZ29142.1 - 0.37 10.5 0.0 0.37 10.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1932) CotJB PF12652.2 CBZ29143.1 - 0.013 15.5 4.5 11 6.1 0.7 4.0 2 2 2 4 4 4 0 CotJB protein HsbA PF12296.3 CBZ29143.1 - 0.014 15.2 2.6 0.37 10.6 0.0 3.2 3 1 0 3 3 3 0 Hydrophobic surface binding protein A Toxin_52 PF15605.1 CBZ29143.1 - 0.024 14.5 2.7 2.2 8.1 0.1 2.6 2 0 0 2 2 2 0 Putative toxin 52 DUF479 PF04336.7 CBZ29143.1 - 0.054 13.5 3.6 0.44 10.6 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF479 Flu_NS2 PF00601.14 CBZ29143.1 - 0.086 13.0 2.0 0.88 9.8 0.1 2.7 2 1 1 3 3 3 0 Influenza non-structural protein (NS2) PGBA_C PF15437.1 CBZ29143.1 - 0.1 12.7 9.6 0.047 13.8 4.0 2.3 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal DUF342 PF03961.8 CBZ29143.1 - 0.13 10.7 3.3 0.16 10.3 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Ras PF00071.17 CBZ29144.1 - 2.5e-22 78.9 0.2 4.8e-18 65.0 0.0 2.6 2 1 0 2 2 2 2 Ras family Miro PF08477.8 CBZ29144.1 - 3e-13 50.3 0.1 1.6e-12 47.9 0.1 2.2 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CBZ29144.1 - 1.1e-07 31.4 0.0 1.9e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CBZ29144.1 - 1.3e-07 30.9 0.0 1.8e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBZ29144.1 - 1.9e-05 24.5 0.0 5.2e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CBZ29144.1 - 4.9e-05 22.5 0.0 0.00086 18.5 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region cobW PF02492.14 CBZ29144.1 - 0.037 13.4 0.1 0.58 9.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 CBZ29144.1 - 0.095 12.5 0.1 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Aa_trans PF01490.13 CBZ29145.1 - 7.6e-48 162.9 44.0 9e-48 162.7 30.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ29145.1 - 0.00021 20.2 34.1 0.0004 19.3 23.6 1.4 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.13 CBZ29146.1 - 8.8e-48 162.7 43.7 1e-47 162.5 30.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ29146.1 - 0.00012 20.9 33.8 0.00026 19.9 23.4 1.5 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF3671 PF12420.3 CBZ29146.1 - 0.42 10.6 0.0 0.42 10.6 0.0 5.0 3 2 2 5 5 5 0 Protein of unknown function KIAA1430 PF13879.1 CBZ29147.1 - 2.6e-19 69.4 4.1 4.3e-19 68.7 2.8 1.3 1 0 0 1 1 1 1 KIAA1430 homologue MRFAP1 PF15155.1 CBZ29147.1 - 0.75 10.1 6.3 0.49 10.7 1.6 2.4 1 1 1 2 2 2 0 MORF4 family-associated protein1 PAPA-1 PF04795.7 CBZ29147.1 - 1.2 9.8 11.5 2.3 8.9 4.5 2.4 2 1 0 2 2 2 0 PAPA-1-like conserved region Imm_superinfect PF14373.1 CBZ29148.1 - 0.012 15.2 0.1 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 Superinfection immunity protein UPF0104 PF03706.8 CBZ29148.1 - 0.013 14.7 0.1 0.013 14.7 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) CD20 PF04103.10 CBZ29148.1 - 0.046 13.6 0.8 0.08 12.8 0.5 1.4 1 1 0 1 1 1 0 CD20-like family DUF2244 PF10003.4 CBZ29148.1 - 0.098 12.0 0.3 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Bax1-I PF01027.15 CBZ29148.1 - 0.16 11.5 0.5 0.18 11.4 0.4 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF998 PF06197.8 CBZ29148.1 - 0.2 10.9 2.2 0.23 10.7 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) YbbR PF07949.7 CBZ29153.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 YbbR-like protein DUF4217 PF13959.1 CBZ29155.1 - 0.0024 17.3 0.0 0.0054 16.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) RRM_1 PF00076.17 CBZ29157.1 - 8.1e-06 25.3 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ29157.1 - 0.00045 20.1 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YhfH PF14149.1 CBZ29157.1 - 0.023 14.4 1.5 0.11 12.2 0.1 2.4 2 0 0 2 2 2 0 YhfH-like protein RRM_1 PF00076.17 CBZ29158.1 - 2.2e-08 33.5 0.0 4.2e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ29158.1 - 0.00019 21.3 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SET PF00856.23 CBZ29160.1 - 0.00011 22.6 0.0 0.0025 18.1 0.0 2.3 1 1 0 1 1 1 1 SET domain BPL_LplA_LipB PF03099.14 CBZ29161.1 - 3.6e-15 56.0 0.0 6.2e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Nup54 PF13874.1 CBZ29162.1 - 0.0049 16.5 1.6 0.0049 16.5 1.1 1.6 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 AIP3 PF03915.8 CBZ29162.1 - 0.011 14.7 1.4 0.017 14.0 1.0 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Baculo_PEP_C PF04513.7 CBZ29162.1 - 0.15 11.8 0.2 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Caps_synth_GfcC PF06251.6 CBZ29162.1 - 0.21 10.7 0.3 0.34 10.0 0.2 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC DUF148 PF02520.12 CBZ29162.1 - 0.44 10.3 1.7 0.73 9.6 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF148 OmpH PF03938.9 CBZ29162.1 - 0.81 9.6 3.7 1.5 8.7 2.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF904 PF06005.7 CBZ29162.1 - 1.5 9.1 3.4 31 4.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Cluap1 PF10234.4 CBZ29162.1 - 1.7 7.8 6.4 3.9 6.5 3.4 1.8 1 1 0 1 1 1 0 Clusterin-associated protein-1 HrpB7 PF09486.5 CBZ29162.1 - 2.2 8.1 12.7 0.66 9.8 0.1 2.8 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) TBPIP PF07106.8 CBZ29162.1 - 3.1 7.3 5.3 4.1 6.9 1.3 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4498 PF14926.1 CBZ29164.1 - 2.2e-18 66.3 0.0 1.2e-11 44.1 0.0 4.3 4 1 0 4 4 4 3 Domain of unknown function (DUF4498) EMP24_GP25L PF01105.19 CBZ29165.1 - 1.1e-25 90.3 0.0 1.3e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Gypsy PF07253.6 CBZ29165.1 - 0.0027 16.1 0.4 0.0036 15.6 0.3 1.1 1 0 0 1 1 1 1 Gypsy protein DUF1843 PF08898.5 CBZ29165.1 - 0.16 12.0 0.4 0.28 11.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) EMP24_GP25L PF01105.19 CBZ29166.1 - 7.3e-20 71.4 0.0 8.3e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_M20 PF01546.23 CBZ29167.1 - 4.6e-27 94.7 0.1 5.7e-27 94.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ29167.1 - 2e-08 33.9 0.0 4.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain TMEM219 PF14940.1 CBZ29167.1 - 0.02 14.0 0.2 0.034 13.2 0.1 1.3 1 0 0 1 1 1 0 Transmembrane 219 Abhydrolase_6 PF12697.2 CBZ29168.1 - 6.1e-27 94.9 0.0 8.6e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ29168.1 - 2.3e-21 76.0 0.0 9.4e-21 74.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CBZ29168.1 - 5.9e-21 74.1 0.0 1.1e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 CBZ29168.1 - 5.5e-09 35.5 0.1 7.8e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CBZ29168.1 - 2.5e-08 33.7 0.0 8e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CBZ29168.1 - 0.00015 21.2 0.0 0.0074 15.7 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 CBZ29168.1 - 0.00018 20.9 0.2 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 CBZ29168.1 - 0.00063 19.2 0.0 0.0013 18.2 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 CBZ29168.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 CBZ29168.1 - 0.0015 17.8 0.0 0.2 10.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Thioesterase PF00975.15 CBZ29168.1 - 0.0021 18.3 0.0 0.0036 17.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 CBZ29168.1 - 0.0056 16.2 0.0 0.02 14.4 0.0 2.0 2 1 0 2 2 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CBZ29168.1 - 0.0065 16.0 0.0 0.0097 15.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF2920 PF11144.3 CBZ29168.1 - 0.012 14.6 0.0 0.6 9.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2920) Ser_hydrolase PF06821.8 CBZ29168.1 - 0.023 14.2 0.0 1.7 8.2 0.0 2.2 1 1 1 2 2 2 0 Serine hydrolase AXE1 PF05448.7 CBZ29168.1 - 0.039 12.4 1.1 3 6.2 0.0 2.8 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.20 CBZ29168.1 - 0.061 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 CBZ29168.1 - 0.11 11.8 0.0 0.48 9.8 0.0 1.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_7 PF12715.2 CBZ29168.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase family LRR_4 PF12799.2 CBZ29170.1 - 4.3e-15 54.9 3.3 0.0012 18.3 0.0 6.3 3 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ29170.1 - 8.3e-07 28.6 8.3 0.29 10.8 0.3 5.0 3 1 0 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 CBZ29170.1 - 0.0092 15.8 16.3 7.7 6.9 0.0 7.5 6 2 1 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ29170.1 - 8.1 7.1 23.9 12 6.6 0.1 8.2 7 1 0 7 7 7 0 Leucine rich repeat Cyt-b5 PF00173.23 CBZ29171.1 - 5.2e-06 26.1 0.0 7.8e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.23 CBZ29172.1 - 3.1e-07 30.0 0.0 5.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RskA PF10099.4 CBZ29172.1 - 0.02 14.6 0.9 0.059 13.0 0.7 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Kinase-PPPase PF03618.9 CBZ29172.1 - 0.032 13.7 0.0 0.039 13.4 0.0 1.0 1 0 0 1 1 1 0 Kinase/pyrophosphorylase TPR_14 PF13428.1 CBZ29172.1 - 0.12 13.1 0.8 1.1 10.0 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Cyt-b5 PF00173.23 CBZ29173.1 - 9.2e-06 25.3 0.1 1.4e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.23 CBZ29174.1 - 3.5e-09 36.3 0.0 5.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.23 CBZ29175.1 - 1.5e-08 34.3 0.0 2.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2721 PF11026.3 CBZ29175.1 - 0.053 13.1 0.3 0.084 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF3638 PF12340.3 CBZ29176.1 - 5e-28 97.6 0.2 5.3e-24 84.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.3 CBZ29176.1 - 8.9e-17 59.9 0.5 2.7e-16 58.3 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-RanBP PF00641.13 CBZ29176.1 - 9.8e-08 30.9 22.2 0.00012 21.1 3.3 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Thioredoxin_8 PF13905.1 CBZ29176.1 - 0.00019 21.4 0.0 0.00047 20.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like ubiquitin PF00240.18 CBZ29176.1 - 0.00053 19.3 0.0 0.0012 18.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family WIYLD PF10440.4 CBZ29176.1 - 0.23 11.4 0.0 0.7 9.8 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-binding WIYLD domain TMEM51 PF15345.1 CBZ29176.1 - 1.4 8.5 5.3 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 COPI_assoc PF08507.5 CBZ29176.1 - 2.5 7.7 0.0 4.8 6.8 0.0 1.4 1 0 0 1 1 1 0 COPI associated protein H_PPase PF03030.11 CBZ29177.1 - 6.4e-251 834.4 34.3 7.8e-251 834.1 23.8 1.1 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase LRR_6 PF13516.1 CBZ29178.1 - 0.00023 20.8 7.8 0.47 10.6 0.0 5.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 CBZ29178.1 - 0.0093 15.5 3.9 1.4 8.6 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ29178.1 - 0.014 15.3 5.1 0.43 10.7 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat GvpG PF05120.7 CBZ29178.1 - 0.081 12.7 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Gas vesicle protein G DUF848 PF05852.6 CBZ29178.1 - 0.1 12.4 0.8 0.27 11.0 0.5 1.7 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) LRR_7 PF13504.1 CBZ29178.1 - 1 9.8 4.8 44 4.9 0.0 4.8 4 0 0 4 4 4 0 Leucine rich repeat MT PF12777.2 CBZ29181.1 - 6.1e-06 25.2 0.1 6.1e-06 25.2 0.1 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Ribonuc_2-5A PF06479.7 CBZ29181.1 - 0.00012 21.9 3.0 0.038 13.8 0.1 2.6 2 0 0 2 2 2 2 Ribonuclease 2-5A Syntaxin-6_N PF09177.6 CBZ29181.1 - 0.45 10.9 16.0 0.51 10.7 0.3 3.9 4 0 0 4 4 4 0 Syntaxin 6, N-terminal RasGAP_C PF03836.10 CBZ29181.1 - 0.91 9.2 7.8 10 5.7 0.4 3.0 2 0 0 2 2 2 0 RasGAP C-terminus ACT PF01842.20 CBZ29181.1 - 1.3 8.6 3.5 6 6.4 0.0 3.3 4 0 0 4 4 4 0 ACT domain Bacillus_HBL PF05791.6 CBZ29181.1 - 2.5 7.4 8.7 11 5.3 0.1 3.4 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF3138 PF11336.3 CBZ29181.1 - 6.1 4.8 8.1 0.56 8.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) ABC_membrane PF00664.18 CBZ29182.1 - 4.6e-51 173.8 28.5 3.9e-26 92.0 6.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ29182.1 - 1e-45 155.3 0.0 2.9e-23 82.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 CBZ29182.1 - 1.1e-11 44.0 1.7 3.5e-06 26.4 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.14 CBZ29182.1 - 1.1e-09 37.8 0.0 0.019 14.1 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBZ29182.1 - 7.4e-09 35.9 0.0 0.027 14.4 0.0 4.1 3 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 CBZ29182.1 - 1.8e-08 33.9 0.5 9.5e-05 21.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CBZ29182.1 - 9.2e-08 32.6 0.0 9.5e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CBZ29182.1 - 6.2e-07 28.5 0.0 0.0062 15.4 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 CBZ29182.1 - 1.2e-06 28.6 0.2 0.0034 17.4 0.0 3.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 CBZ29182.1 - 2.6e-06 27.0 0.3 0.019 14.4 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 CBZ29182.1 - 1.2e-05 24.9 0.2 0.033 13.6 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CBZ29182.1 - 2.1e-05 24.4 0.2 0.21 11.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_19 PF13245.1 CBZ29182.1 - 4.2e-05 23.2 2.6 0.0042 16.7 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain Dynamin_N PF00350.18 CBZ29182.1 - 0.00015 21.6 0.5 0.028 14.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 CBZ29182.1 - 0.00019 20.6 0.2 0.011 14.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 CBZ29182.1 - 0.0003 20.4 0.3 0.089 12.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.12 CBZ29182.1 - 0.00031 20.6 0.7 0.53 10.0 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 ArgK PF03308.11 CBZ29182.1 - 0.00033 19.5 0.4 0.25 10.1 0.0 2.3 2 0 0 2 2 2 2 ArgK protein MobB PF03205.9 CBZ29182.1 - 0.00038 20.1 1.1 0.52 10.0 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CBZ29182.1 - 0.00055 20.0 0.5 0.19 11.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 CBZ29182.1 - 0.00069 20.4 0.0 2.6 8.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CBZ29182.1 - 0.0011 19.4 1.8 1 9.8 0.2 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 CBZ29182.1 - 0.0015 18.1 1.0 1.1 8.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 CBZ29182.1 - 0.0019 18.0 0.1 0.22 11.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBZ29182.1 - 0.0056 16.3 0.4 0.44 10.2 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase CAP_GLY PF01302.20 CBZ29182.1 - 0.012 15.2 0.5 0.043 13.5 0.3 1.9 1 1 0 1 1 1 0 CAP-Gly domain ATP_bind_1 PF03029.12 CBZ29182.1 - 0.021 14.4 0.7 4.6 6.7 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 CBZ29182.1 - 0.025 13.2 0.4 1.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 CBZ29182.1 - 0.028 14.7 1.5 5.3 7.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.13 CBZ29182.1 - 0.041 13.3 0.2 4.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.10 CBZ29182.1 - 0.049 12.2 0.1 0.27 9.8 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein cobW PF02492.14 CBZ29182.1 - 0.055 12.9 5.8 0.71 9.2 0.1 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 CBZ29182.1 - 0.057 13.5 0.1 2.2 8.4 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_5 PF07728.9 CBZ29182.1 - 0.12 12.0 0.1 8.2 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 CBZ29182.1 - 0.16 11.4 0.9 2.3 7.6 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 CBZ29182.1 - 0.16 11.6 0.4 21 4.7 0.0 2.5 2 0 0 2 2 2 0 NTPase GTP_EFTU PF00009.22 CBZ29182.1 - 0.3 10.5 0.4 4.6 6.6 0.0 2.5 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain DAP3 PF10236.4 CBZ29182.1 - 0.34 9.7 0.6 13 4.5 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Guanylate_kin PF00625.16 CBZ29182.1 - 0.42 10.0 0.0 0.8 9.1 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase AAA_14 PF13173.1 CBZ29182.1 - 0.8 9.6 2.4 4.8 7.1 0.0 2.7 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.4 CBZ29182.1 - 2.5 6.5 4.1 0.89 8.0 0.1 2.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_15 PF13175.1 CBZ29182.1 - 2.9 6.8 0.0 30 3.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_membrane PF00664.18 CBZ29183.1 - 3.9e-47 160.9 17.9 6.9e-26 91.2 5.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ29183.1 - 2.4e-46 157.4 0.0 2.6e-23 82.8 0.0 2.9 3 0 0 3 3 3 2 ABC transporter AAA_29 PF13555.1 CBZ29183.1 - 1.7e-11 43.4 0.1 3.7e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CBZ29183.1 - 1.1e-09 37.8 0.0 0.024 13.8 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBZ29183.1 - 6.8e-09 36.0 0.0 0.026 14.5 0.0 4.1 3 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 CBZ29183.1 - 9.8e-09 34.8 0.1 8.8e-05 21.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CBZ29183.1 - 9.1e-08 32.6 0.0 9.9e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CBZ29183.1 - 1.9e-07 30.2 0.0 0.0061 15.4 0.0 3.0 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_16 PF13191.1 CBZ29183.1 - 8.2e-07 29.1 0.9 0.0014 18.6 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_10 PF12846.2 CBZ29183.1 - 2.3e-06 27.3 0.3 0.017 14.5 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 CBZ29183.1 - 1e-05 25.1 0.2 0.031 13.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_19 PF13245.1 CBZ29183.1 - 2.1e-05 24.2 2.6 0.0039 16.9 0.1 3.5 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 CBZ29183.1 - 3.7e-05 23.6 0.2 0.37 10.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBZ29183.1 - 0.00012 22.0 0.5 0.026 14.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family ArgK PF03308.11 CBZ29183.1 - 0.0002 20.2 0.5 0.16 10.6 0.0 2.3 2 0 0 2 2 2 2 ArgK protein DUF258 PF03193.11 CBZ29183.1 - 0.00028 20.1 0.1 0.019 14.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 CBZ29183.1 - 0.00029 20.5 0.2 0.074 12.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.12 CBZ29183.1 - 0.00031 20.6 0.9 0.49 10.1 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 MobB PF03205.9 CBZ29183.1 - 0.00036 20.2 1.1 0.48 10.1 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 CBZ29183.1 - 0.00038 20.5 0.4 0.15 12.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 CBZ29183.1 - 0.00054 20.7 0.0 2.4 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CBZ29183.1 - 0.001 19.5 1.8 0.96 9.9 0.2 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 CBZ29183.1 - 0.0011 18.6 1.0 0.94 9.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 CBZ29183.1 - 0.0015 18.4 0.1 0.2 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CBZ29183.1 - 0.0048 16.6 0.3 0.39 10.3 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 CBZ29183.1 - 0.0062 16.0 2.2 0.66 9.3 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CAP_GLY PF01302.20 CBZ29183.1 - 0.011 15.4 0.5 0.039 13.6 0.3 1.9 1 1 0 1 1 1 0 CAP-Gly domain ATP_bind_1 PF03029.12 CBZ29183.1 - 0.017 14.6 0.7 4.3 6.8 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 CBZ29183.1 - 0.019 15.2 0.4 4.8 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CBZ29183.1 - 0.02 13.5 0.2 1.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.13 CBZ29183.1 - 0.04 13.4 0.2 4.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CBZ29183.1 - 0.051 13.7 0.1 2 8.6 0.0 2.8 3 0 0 3 3 2 0 RNA helicase Adeno_IVa2 PF02456.10 CBZ29183.1 - 0.063 11.9 0.1 0.29 9.7 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.9 CBZ29183.1 - 0.096 12.4 0.1 7.6 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 CBZ29183.1 - 0.15 11.5 0.6 2.2 7.7 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 CBZ29183.1 - 0.15 11.7 0.4 20 4.8 0.0 2.4 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.7 CBZ29183.1 - 0.19 10.7 0.1 8.2 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 CBZ29183.1 - 0.3 10.9 0.7 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 CBZ29183.1 - 0.3 10.4 0.1 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Guanylate_kin PF00625.16 CBZ29183.1 - 0.38 10.1 0.0 0.74 9.2 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase DAP3 PF10236.4 CBZ29183.1 - 0.38 9.6 0.5 12 4.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 CBZ29184.1 - 5.2e-46 156.3 0.0 2.6e-23 82.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBZ29184.1 - 7.5e-40 137.0 22.0 4.3e-22 78.8 6.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.1 CBZ29184.1 - 1.7e-11 43.4 0.1 3.7e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CBZ29184.1 - 1.1e-09 37.8 0.0 0.024 13.8 0.0 4.1 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBZ29184.1 - 7e-09 36.0 0.0 0.025 14.5 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_25 PF13481.1 CBZ29184.1 - 1.1e-08 34.7 0.1 9e-05 21.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CBZ29184.1 - 9.2e-08 32.6 0.0 9.9e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CBZ29184.1 - 6.7e-07 28.4 0.0 0.006 15.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 CBZ29184.1 - 1e-06 28.8 1.1 0.0013 18.7 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_10 PF12846.2 CBZ29184.1 - 2.1e-06 27.4 0.3 0.017 14.5 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 CBZ29184.1 - 9.2e-06 25.2 0.1 0.032 13.7 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_19 PF13245.1 CBZ29184.1 - 2.5e-05 23.9 2.6 0.0039 16.9 0.1 3.3 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 CBZ29184.1 - 3.8e-05 23.6 0.2 0.38 10.7 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBZ29184.1 - 0.00012 21.9 0.5 0.026 14.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family ArgK PF03308.11 CBZ29184.1 - 0.00021 20.1 0.4 0.17 10.6 0.0 2.3 2 0 0 2 2 2 2 ArgK protein NACHT PF05729.7 CBZ29184.1 - 0.00022 20.9 0.2 0.075 12.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain DUF258 PF03193.11 CBZ29184.1 - 0.00028 20.1 0.1 0.019 14.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DUF87 PF01935.12 CBZ29184.1 - 0.00033 20.5 0.9 0.49 10.1 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_22 PF13401.1 CBZ29184.1 - 0.00039 20.5 0.4 0.16 12.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 CBZ29184.1 - 0.00041 20.0 1.1 0.49 10.1 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CBZ29184.1 - 0.00053 20.8 0.0 2.4 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CBZ29184.1 - 0.00079 19.0 0.1 0.95 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CBZ29184.1 - 0.001 19.5 1.8 0.97 9.9 0.2 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 CBZ29184.1 - 0.002 17.9 1.0 0.2 11.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 CBZ29184.1 - 0.0047 16.6 0.3 0.4 10.3 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase CAP_GLY PF01302.20 CBZ29184.1 - 0.0071 16.0 0.5 0.036 13.7 0.3 2.1 1 1 0 1 1 1 1 CAP-Gly domain cobW PF02492.14 CBZ29184.1 - 0.0079 15.6 2.2 0.66 9.3 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CBZ29184.1 - 0.011 16.0 0.5 4.9 7.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 CBZ29184.1 - 0.018 14.5 0.7 4.3 6.8 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.4 CBZ29184.1 - 0.02 13.5 0.2 1.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Viral_helicase1 PF01443.13 CBZ29184.1 - 0.039 13.4 0.2 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 CBZ29184.1 - 0.054 13.6 0.1 2 8.6 0.0 2.8 3 0 0 3 3 2 0 RNA helicase Adeno_IVa2 PF02456.10 CBZ29184.1 - 0.058 12.0 0.1 0.29 9.7 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.9 CBZ29184.1 - 0.089 12.5 0.1 7.6 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CBZ29184.1 - 0.15 11.7 0.4 20 4.8 0.0 2.5 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.7 CBZ29184.1 - 0.17 10.9 0.1 8.3 5.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.20 CBZ29184.1 - 0.2 11.1 0.5 2.2 7.7 0.0 2.4 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain GTP_EFTU PF00009.22 CBZ29184.1 - 0.3 10.5 0.1 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 CBZ29184.1 - 0.3 10.9 0.7 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 CBZ29184.1 - 0.31 10.4 0.0 0.74 9.2 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase DAP3 PF10236.4 CBZ29184.1 - 0.38 9.6 0.5 13 4.6 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_ATPase PF09818.4 CBZ29184.1 - 0.83 8.1 2.6 0.79 8.2 0.0 2.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class PP2C PF00481.16 CBZ29187.1 - 7.6e-33 113.9 0.0 5.3e-28 98.1 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C zf-UBP PF02148.14 CBZ29187.1 - 0.054 13.6 10.0 0.16 12.1 7.0 1.8 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein CSD PF00313.17 CBZ29188.1 - 7.8e-08 31.9 0.1 0.0002 21.1 0.0 2.5 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain CSD PF00313.17 CBZ29189.1 - 6.1e-12 45.1 0.0 5.5e-08 32.4 0.0 2.6 3 0 0 3 3 3 2 'Cold-shock' DNA-binding domain CSD PF00313.17 CBZ29190.1 - 0.0004 20.1 0.1 0.61 9.9 0.0 2.5 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain AAA_13 PF13166.1 CBZ29191.1 - 1 7.7 6.6 0.13 10.7 1.0 1.8 1 1 1 2 2 2 0 AAA domain Med11 PF10280.4 CBZ29191.1 - 4 7.5 8.3 0.41 10.6 0.2 2.9 2 1 1 3 3 3 0 Mediator complex protein HALZ PF02183.13 CBZ29191.1 - 8.8 6.1 21.6 0.9 9.3 0.7 5.1 5 1 1 6 6 6 0 Homeobox associated leucine zipper SPRY PF00622.23 CBZ29192.1 - 0.00027 21.0 0.0 0.00062 19.8 0.0 1.5 1 0 0 1 1 1 1 SPRY domain HHA PF05321.6 CBZ29193.1 - 0.065 13.3 2.4 0.22 11.6 0.5 2.9 2 0 0 2 2 2 0 Haemolysin expression modulating protein SDA1 PF05285.7 CBZ29194.1 - 0.2 10.9 1.4 0.3 10.3 1.0 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 CBZ29194.1 - 0.27 9.1 2.4 0.36 8.6 1.6 1.1 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 CBZ29194.1 - 0.85 8.5 1.8 1.4 7.8 1.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit zf-LSD1 PF06943.7 CBZ29195.1 - 4.6e-12 45.3 5.9 4.6e-12 45.3 4.1 2.8 2 1 1 3 3 3 1 LSD1 zinc finger Mu-like_Com PF10122.4 CBZ29195.1 - 0.71 8.9 13.5 0.43 9.6 0.3 2.7 1 1 2 3 3 3 0 Mu-like prophage protein Com Tmemb_55A PF09788.4 CBZ29195.1 - 0.93 8.5 17.1 1.8 7.6 11.8 1.4 1 1 0 1 1 1 0 Transmembrane protein 55A zinc_ribbon_4 PF13717.1 CBZ29195.1 - 1.1 9.0 0.0 1.1 9.0 0.0 4.0 3 1 1 5 5 5 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBZ29195.1 - 1.1 8.8 0.0 1.1 8.8 0.0 4.0 3 1 1 4 4 4 0 zinc-ribbon domain zf-C3HC4_4 PF15227.1 CBZ29195.1 - 2.6 7.9 13.6 5.5 6.9 0.0 3.3 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-MYND PF01753.13 CBZ29195.1 - 4.2 7.3 9.6 5.2 7.0 0.1 2.6 2 1 0 2 2 2 0 MYND finger Stc1 PF12898.2 CBZ29195.1 - 5.6 7.1 9.1 0.31 11.1 0.4 2.3 1 1 1 2 2 2 0 Stc1 domain ABC_tran PF00005.22 CBZ29199.1 - 6.6e-41 139.8 0.0 1.1e-24 87.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBZ29199.1 - 1.8e-35 122.7 15.4 7.1e-22 78.1 1.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 CBZ29199.1 - 6.9e-09 35.2 0.1 0.11 11.7 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBZ29199.1 - 1.8e-07 30.5 0.1 0.017 14.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CBZ29199.1 - 3.2e-06 27.3 0.0 1.2 9.0 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 CBZ29199.1 - 3.6e-06 26.5 0.0 0.037 13.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CBZ29199.1 - 1.2e-05 24.8 0.0 0.053 12.9 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family T2SE PF00437.15 CBZ29199.1 - 3.2e-05 22.9 0.0 0.23 10.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein CAP_GLY PF01302.20 CBZ29199.1 - 4.5e-05 23.0 0.1 0.00012 21.7 0.1 1.7 1 0 0 1 1 1 1 CAP-Gly domain AAA_16 PF13191.1 CBZ29199.1 - 5.9e-05 23.1 1.2 0.42 10.5 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_10 PF12846.2 CBZ29199.1 - 8e-05 22.2 0.5 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_23 PF13476.1 CBZ29199.1 - 0.00019 21.8 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.4 CBZ29199.1 - 0.0005 18.8 0.3 0.49 8.9 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.18 CBZ29199.1 - 0.0011 18.8 0.3 0.53 10.2 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBZ29199.1 - 0.0048 17.0 0.5 1.8 8.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 CBZ29199.1 - 0.0076 15.0 0.4 2.3 6.9 0.1 2.4 2 0 0 2 2 2 1 ArgK protein NACHT PF05729.7 CBZ29199.1 - 0.013 15.1 0.9 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.12 CBZ29199.1 - 0.013 15.2 4.4 0.67 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 Miro PF08477.8 CBZ29199.1 - 0.014 15.9 3.0 1.1 9.7 0.2 2.5 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 CBZ29199.1 - 0.025 14.2 1.6 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 CBZ29199.1 - 0.027 13.6 0.2 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 CBZ29199.1 - 0.086 11.9 0.0 7.7 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.20 CBZ29199.1 - 0.13 11.7 2.0 3.2 7.1 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 CBZ29199.1 - 0.22 10.9 4.4 4.2 6.7 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 CBZ29199.1 - 0.27 10.8 0.0 25 4.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase KaiC PF06745.8 CBZ29199.1 - 0.28 10.2 0.6 13 4.8 0.0 2.6 3 0 0 3 3 3 0 KaiC DAP3 PF10236.4 CBZ29199.1 - 0.29 10.0 0.6 9.6 5.0 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Pox_A32 PF04665.7 CBZ29199.1 - 0.34 10.1 0.8 22 4.2 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 CBZ29199.1 - 0.38 10.6 3.3 5.2 6.9 0.2 2.8 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.17 CBZ29199.1 - 0.45 9.3 0.4 12 4.6 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.1 CBZ29199.1 - 0.53 11.1 3.3 5.7 7.7 0.4 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CBZ29199.1 - 0.53 10.0 3.0 17 5.2 0.1 2.3 2 0 0 2 2 2 0 Dynamin family DUF2075 PF09848.4 CBZ29199.1 - 2.1 7.2 2.0 2.7 6.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AIG1 PF04548.11 CBZ29199.1 - 3.9 6.5 3.2 7.8 5.5 0.0 2.4 3 0 0 3 3 2 0 AIG1 family LRR_4 PF12799.2 CBZ29200.1 - 1.6e-07 30.7 0.0 0.019 14.5 0.0 3.5 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ29200.1 - 5.4e-07 29.2 0.1 0.0049 16.6 0.1 2.7 2 1 0 2 2 2 2 Leucine rich repeat Cytadhesin_P30 PF07271.6 CBZ29200.1 - 0.0022 17.3 8.2 0.0032 16.7 5.7 1.2 1 0 0 1 1 1 1 Cytadhesin P30/P32 LRRNT_2 PF08263.7 CBZ29200.1 - 0.046 13.6 0.1 0.046 13.6 0.1 2.9 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain Amelogenin PF02948.10 CBZ29200.1 - 1.3 9.6 6.7 2.5 8.7 4.7 1.4 1 0 0 1 1 1 0 Amelogenin LRR_4 PF12799.2 CBZ29201.1 - 1.2e-07 31.1 0.0 0.024 14.2 0.0 3.6 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ29201.1 - 2e-07 30.6 0.3 0.0044 16.7 0.2 3.0 2 2 1 3 3 3 2 Leucine rich repeat LRRNT_2 PF08263.7 CBZ29201.1 - 0.044 13.7 0.2 0.044 13.7 0.1 3.1 5 0 0 5 5 5 0 Leucine rich repeat N-terminal domain LRR_4 PF12799.2 CBZ29202.1 - 9.8e-08 31.4 0.1 0.066 12.8 0.1 3.3 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ29202.1 - 0.0009 18.9 0.0 0.13 12.0 0.0 2.3 1 1 0 2 2 2 1 Leucine rich repeat LRRNT_2 PF08263.7 CBZ29202.1 - 0.06 13.3 3.0 0.063 13.2 0.3 2.5 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain TFIIA PF03153.8 CBZ29202.1 - 1.2 9.0 4.2 1.4 8.6 2.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PRCC PF10253.4 CBZ29202.1 - 3 8.5 5.4 5.4 7.6 3.7 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting LRR_4 PF12799.2 CBZ29203.1 - 1.1e-07 31.2 0.6 0.0023 17.5 0.2 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ29203.1 - 1.3e-05 24.8 0.0 0.025 14.3 0.0 2.7 2 1 1 3 3 3 3 Leucine rich repeat DUF3338 PF11819.3 CBZ29203.1 - 0.042 13.2 0.0 11 5.5 0.0 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3338) LRR_4 PF12799.2 CBZ29205.1 - 3.5e-25 87.1 0.1 0.00014 21.4 0.0 10.9 10 1 0 11 11 11 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBZ29205.1 - 4.3e-12 44.7 13.0 2.7 8.3 0.0 12.1 15 0 0 15 15 15 3 Leucine Rich repeat LRR_8 PF13855.1 CBZ29205.1 - 4e-11 42.4 14.7 0.00073 19.2 0.1 9.4 10 1 0 10 10 10 2 Leucine rich repeat LRR_1 PF00560.28 CBZ29205.1 - 0.0093 15.8 26.0 14 6.1 0.3 12.2 13 2 1 14 14 14 1 Leucine Rich Repeat Paramyxo_PNT PF13825.1 CBZ29205.1 - 0.016 14.4 0.7 0.029 13.5 0.5 1.3 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus LRR_7 PF13504.1 CBZ29205.1 - 6.1 7.5 32.2 49 4.7 0.0 12.4 17 0 0 17 17 17 0 Leucine rich repeat Daxx PF03344.10 CBZ29207.1 - 0.025 13.1 0.5 0.044 12.2 0.3 1.3 1 0 0 1 1 1 0 Daxx Family BLVR PF06375.6 CBZ29207.1 - 0.39 10.5 2.2 0.74 9.6 1.5 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Pkinase PF00069.20 CBZ29210.1 - 5e-37 127.4 0.0 1.4e-25 89.9 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29210.1 - 2.1e-21 76.1 0.0 7.3e-10 38.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase PH_3 PF14593.1 CBZ29210.1 - 0.00023 20.9 0.0 0.0012 18.7 0.0 2.0 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.1 CBZ29210.1 - 0.044 12.7 0.0 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Kinase-like L51_S25_CI-B8 PF05047.11 CBZ29212.1 - 1.8e-10 40.3 0.0 3.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LysR_substrate PF03466.15 CBZ29212.1 - 0.11 11.5 0.3 0.43 9.6 0.0 1.9 2 0 0 2 2 2 0 LysR substrate binding domain DUF2877 PF11392.3 CBZ29213.1 - 0.022 14.9 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2877) DUF1658 PF07871.6 CBZ29214.1 - 0.025 14.1 0.0 0.077 12.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) Peptidase_C7 PF01830.13 CBZ29214.1 - 0.08 12.0 0.3 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Peptidase C7 family Cmc1 PF08583.5 CBZ29215.1 - 0.4 10.5 3.7 1 9.2 2.5 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ribosomal_L36 PF00444.13 CBZ29216.1 - 0.006 16.5 0.5 0.014 15.4 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L36 LRR_4 PF12799.2 CBZ29217.1 - 8e-47 156.1 23.4 2.2e-05 23.9 0.5 11.9 9 2 2 12 12 12 11 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBZ29217.1 - 4.7e-18 63.1 33.2 0.0067 16.3 0.1 16.8 20 0 0 20 20 20 5 Leucine Rich repeat LRR_8 PF13855.1 CBZ29217.1 - 1.8e-15 56.4 32.8 0.00021 20.9 2.1 10.4 4 3 8 13 13 13 11 Leucine rich repeat LRR_1 PF00560.28 CBZ29217.1 - 7.2e-06 25.3 24.3 24 5.4 0.9 14.3 15 4 2 17 17 17 1 Leucine Rich Repeat LRR_9 PF14580.1 CBZ29217.1 - 0.029 13.9 8.5 15 5.0 0.2 4.8 2 2 2 4 4 4 0 Leucine-rich repeat TP_methylase PF00590.15 CBZ29218.1 - 2.3e-17 63.4 0.0 4e-17 62.6 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 CBZ29218.1 - 0.0041 16.8 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) NolV PF06635.7 CBZ29218.1 - 0.0052 15.9 0.0 0.0086 15.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein NolV NTPase_I-T PF01931.13 CBZ29219.1 - 2e-64 216.3 0.0 2.2e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Thiolase_N PF00108.18 CBZ29220.1 - 2.4e-44 151.3 0.2 3.2e-44 150.8 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBZ29220.1 - 1.6e-34 117.9 0.0 3.6e-34 116.8 0.0 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CBZ29220.1 - 7.3e-05 22.3 2.3 0.0002 20.9 1.6 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 CBZ29220.1 - 0.024 13.0 0.0 0.055 11.9 0.0 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) ACP_syn_III PF08545.5 CBZ29220.1 - 0.099 12.3 0.9 3.8 7.2 0.3 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 CBZ29221.1 - 5.5e-63 212.4 0.2 7.2e-63 212.0 0.1 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CBZ29221.1 - 2.8e-35 120.3 0.0 8.2e-35 118.9 0.0 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain SpoVAD PF07451.6 CBZ29221.1 - 1.7e-05 23.4 0.0 3.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) ketoacyl-synt PF00109.21 CBZ29221.1 - 6e-05 22.6 1.9 0.00016 21.2 1.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAE1_CUT1_RppA PF08392.7 CBZ29221.1 - 0.0019 17.3 0.2 0.0039 16.3 0.2 1.4 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.5 CBZ29221.1 - 0.1 12.2 0.9 4.3 7.0 0.3 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III zf-MYND PF01753.13 CBZ29222.1 - 5.1e-11 42.2 8.5 5.1e-11 42.2 5.9 2.2 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 CBZ29222.1 - 0.97 9.3 8.0 1.2 9.0 4.3 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Sld5 PF05916.6 CBZ29223.1 - 3e-06 27.4 0.0 3.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein UME PF08064.8 CBZ29226.1 - 0.066 13.1 0.6 1 9.3 0.1 2.7 2 0 0 2 2 2 0 UME (NUC010) domain PPR_3 PF13812.1 CBZ29227.1 - 0.039 14.2 5.8 1 9.8 0.0 4.3 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 CBZ29227.1 - 0.053 13.5 0.7 94 3.1 0.0 4.3 5 0 0 5 5 5 0 PPR repeat family Cullin_Nedd8 PF10557.4 CBZ29229.1 - 2.8e-15 55.9 1.6 6.1e-15 54.8 1.1 1.6 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.17 CBZ29229.1 - 0.00021 20.0 0.0 0.0019 16.8 0.0 2.2 2 1 0 2 2 2 1 Cullin family NAP PF00956.13 CBZ29232.1 - 9.3e-76 254.1 0.3 9.3e-76 254.1 0.2 1.9 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) HAUS6_N PF14661.1 CBZ29232.1 - 0.013 14.8 0.3 0.028 13.7 0.2 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CENP-B_dimeris PF09026.5 CBZ29232.1 - 0.17 12.1 20.3 0.91 9.8 7.9 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Spt5_N PF11942.3 CBZ29232.1 - 0.48 11.0 17.7 0.47 11.1 3.7 3.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 CBZ29232.1 - 0.61 10.4 16.9 4.8 7.5 1.8 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.7 CBZ29232.1 - 1 7.2 12.9 1.5 6.6 9.0 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2189 PF09955.4 CBZ29234.1 - 0.013 15.4 2.8 0.013 15.4 1.9 2.8 3 0 0 3 3 3 0 Predicted integral membrane protein (DUF2189) TRAM_LAG1_CLN8 PF03798.11 CBZ29235.1 - 5.9e-36 123.8 16.8 5.9e-36 123.8 11.7 2.2 2 1 0 2 2 2 1 TLC domain CCSMST1 PF15013.1 CBZ29235.1 - 0.17 11.8 0.2 0.17 11.8 0.1 2.5 4 0 0 4 4 4 0 CCSMST1 family Aa_trans PF01490.13 CBZ29236.1 - 1.2e-44 152.4 17.5 1.5e-44 152.1 12.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ29236.1 - 3.9e-09 35.8 9.3 3.9e-09 35.8 6.5 2.4 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family Aa_trans PF01490.13 CBZ29237.1 - 2.4e-44 151.4 17.8 3e-44 151.1 12.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ29237.1 - 4.2e-09 35.7 9.8 4.2e-09 35.7 6.8 2.4 3 0 0 3 3 3 2 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 CBZ29237.1 - 5.1e-08 31.8 25.6 5.1e-08 31.8 17.7 2.1 2 0 0 2 2 2 1 Amino acid permease Pkinase PF00069.20 CBZ29238.1 - 1.4e-17 63.7 0.0 2.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29238.1 - 1.7e-10 40.4 0.0 7.1e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase HAMP PF00672.20 CBZ29238.1 - 1.7e-05 24.8 0.1 1.7e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 HAMP domain Pkinase PF00069.20 CBZ29239.1 - 5.4e-14 51.9 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29239.1 - 9.4e-13 47.8 0.0 5.2e-12 45.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase DUF912 PF06024.7 CBZ29241.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Glycos_transf_1 PF00534.15 CBZ29242.1 - 6.1e-15 55.0 0.0 2.5e-14 53.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBZ29242.1 - 2.4e-09 37.4 0.3 1e-08 35.4 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBZ29242.1 - 2.7e-05 24.3 0.0 7.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_90 PF05686.7 CBZ29242.1 - 0.0035 16.1 0.0 0.0067 15.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glycos_transf_1 PF00534.15 CBZ29243.1 - 1.7e-13 50.3 0.0 6.6e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBZ29243.1 - 2.5e-09 37.3 0.4 1.1e-08 35.3 0.2 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CBZ29244.1 - 1.5e-15 57.0 0.0 9.3e-15 54.4 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBZ29244.1 - 1e-09 38.6 0.4 4.8e-09 36.4 0.3 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBZ29244.1 - 7.7e-06 26.0 0.0 2.2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_90 PF05686.7 CBZ29244.1 - 0.0044 15.7 0.1 0.009 14.7 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 90 Peptidase_M20 PF01546.23 CBZ29245.1 - 1.9e-15 56.8 0.1 2.2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ29245.1 - 1.1e-08 34.7 0.0 2.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 CBZ29245.1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Ribosomal_L40e PF01020.12 CBZ29246.1 - 4.5e-34 115.8 12.7 7.2e-34 115.1 8.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 CBZ29246.1 - 5.9e-34 115.2 0.3 7.8e-34 114.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ29246.1 - 2.1e-20 72.1 0.2 3e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ29246.1 - 7.9e-06 26.0 0.1 3.2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBZ29246.1 - 0.0003 20.5 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBZ29246.1 - 0.0094 15.8 0.1 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Zn_Tnp_IS91 PF14319.1 CBZ29246.1 - 0.063 12.7 2.2 0.091 12.2 1.5 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF2870 PF11069.3 CBZ29246.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) zf-CHY PF05495.7 CBZ29246.1 - 0.099 12.8 3.3 0.15 12.2 2.3 1.2 1 0 0 1 1 1 0 CHY zinc finger DUF2407 PF10302.4 CBZ29246.1 - 0.099 12.8 0.0 0.12 12.6 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain RINGv PF12906.2 CBZ29248.1 - 3.1e-11 43.1 6.2 3.1e-11 43.1 4.3 2.0 2 0 0 2 2 2 1 RING-variant domain DUF4131 PF13567.1 CBZ29248.1 - 2 7.7 4.9 5.7 6.3 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Dus PF01207.12 CBZ29249.1 - 1.6e-50 171.6 0.9 2.3e-20 72.6 0.0 4.1 4 0 0 4 4 4 4 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 CBZ29249.1 - 0.15 10.9 0.0 0.75 8.7 0.0 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Nop25 PF09805.4 CBZ29250.1 - 0.059 13.4 6.9 0.22 11.5 1.2 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF2531 PF10748.4 CBZ29250.1 - 0.07 12.3 0.6 4.8 6.3 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2531) Neur_chan_memb PF02932.11 CBZ29250.1 - 1.4 8.7 5.5 0.61 9.9 1.6 1.9 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Thioredoxin_8 PF13905.1 CBZ29252.1 - 1.4e-22 79.6 0.0 2e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 CBZ29252.1 - 6.1e-10 38.8 0.0 8.4e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin PF00085.15 CBZ29252.1 - 4.1e-09 36.0 0.0 1.8e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CBZ29252.1 - 2e-08 34.4 0.0 2.7e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CBZ29252.1 - 1.3e-07 31.3 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 CBZ29252.1 - 0.00017 21.1 0.1 0.00035 20.1 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 CBZ29252.1 - 0.00025 20.9 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 CBZ29252.1 - 0.00056 19.4 0.0 0.0022 17.4 0.0 1.8 2 0 0 2 2 2 1 F plasmid transfer operon protein Glutaredoxin PF00462.19 CBZ29252.1 - 0.022 14.7 0.2 0.71 9.9 0.1 2.4 1 1 1 2 2 2 0 Glutaredoxin Thioredoxin_8 PF13905.1 CBZ29253.1 - 3.4e-24 84.7 0.0 4.6e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CBZ29253.1 - 9.7e-09 35.4 0.0 1.5e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 CBZ29253.1 - 3.3e-08 33.2 0.0 4.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.15 CBZ29253.1 - 4.2e-08 32.8 0.0 3.2e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.5 CBZ29253.1 - 5.5e-08 32.4 0.0 7.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin TraF PF13728.1 CBZ29253.1 - 3.6e-05 23.3 0.0 0.00012 21.6 0.0 1.7 1 1 1 2 2 2 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 CBZ29253.1 - 4e-05 23.1 0.0 0.00057 19.4 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.1 CBZ29253.1 - 0.00038 20.4 0.0 0.00081 19.3 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like DUF749 PF05370.6 CBZ29253.1 - 0.028 14.3 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF749) Peptidase_M8 PF01457.11 CBZ29256.1 - 1.2e-120 403.3 0.0 2.5e-120 402.3 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M20 PF01546.23 CBZ29258.1 - 5.8e-19 68.3 0.1 1e-18 67.5 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ29258.1 - 6e-13 48.5 0.0 1.1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Ribosomal_L40e PF01020.12 CBZ29259.1 - 4.5e-34 115.8 12.7 7.2e-34 115.1 8.8 1.3 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 CBZ29259.1 - 5.9e-34 115.2 0.3 7.8e-34 114.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ29259.1 - 2.1e-20 72.1 0.2 3e-20 71.6 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ29259.1 - 7.9e-06 26.0 0.1 3.2e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CBZ29259.1 - 0.0003 20.5 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CBZ29259.1 - 0.0094 15.8 0.1 0.019 14.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Zn_Tnp_IS91 PF14319.1 CBZ29259.1 - 0.063 12.7 2.2 0.091 12.2 1.5 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF2870 PF11069.3 CBZ29259.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) zf-CHY PF05495.7 CBZ29259.1 - 0.099 12.8 3.3 0.15 12.2 2.3 1.2 1 0 0 1 1 1 0 CHY zinc finger DUF2407 PF10302.4 CBZ29259.1 - 0.099 12.8 0.0 0.12 12.6 0.0 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain CRAL_TRIO PF00650.15 CBZ29261.1 - 3.3e-47 159.9 0.0 4.7e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CBZ29261.1 - 0.00081 19.3 0.1 0.0063 16.4 0.1 2.1 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain YopR_core PF09025.5 CBZ29261.1 - 0.051 13.5 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 YopR Core CRAL_TRIO_N PF03765.10 CBZ29261.1 - 0.07 13.2 0.6 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.15 CBZ29262.1 - 3.3e-46 156.6 0.0 5.8e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CBZ29262.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Sif PF06767.6 CBZ29262.1 - 0.043 12.5 0.0 0.99 8.1 0.0 2.1 2 0 0 2 2 2 0 Sif protein CRAL_TRIO PF00650.15 CBZ29263.1 - 2.4e-37 127.8 0.0 4e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CBZ29263.1 - 2.5e-05 24.2 0.1 0.00014 21.8 0.0 2.0 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CorA PF01544.13 CBZ29264.1 - 2.1e-05 23.6 3.7 0.0013 17.8 1.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein SR-25 PF10500.4 CBZ29264.1 - 6.8 6.0 21.0 17 4.7 14.5 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RseA_C PF03873.8 CBZ29266.1 - 0.43 10.5 2.8 18 5.2 0.0 3.5 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain tRNA_lig_CPD PF08302.6 CBZ29270.1 - 3.8e-07 29.5 0.0 7.1e-06 25.4 0.0 2.3 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain AAA_33 PF13671.1 CBZ29270.1 - 1.4e-06 28.2 0.0 5.8e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 CBZ29270.1 - 0.00057 19.5 0.0 0.00099 18.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 CBZ29270.1 - 0.0018 17.7 0.0 0.0081 15.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain tRNA_lig_kinase PF08303.6 CBZ29270.1 - 0.0023 17.8 0.0 0.0062 16.4 0.0 1.7 1 1 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 CBZ29270.1 - 0.0027 18.4 0.0 0.0069 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CBZ29270.1 - 0.0028 17.3 0.0 0.0058 16.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CBZ29270.1 - 0.0035 17.6 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ29270.1 - 0.0076 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ29270.1 - 0.012 15.6 0.0 0.33 10.8 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.1 CBZ29270.1 - 0.031 14.2 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 CBZ29270.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBZ29270.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.16 CBZ29272.1 - 3e-56 190.3 0.1 3.5e-56 190.1 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family K_channel_TID PF07941.6 CBZ29278.1 - 0.2 11.9 4.7 0.12 12.5 0.7 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain ECH PF00378.15 CBZ29283.1 - 5.6e-48 163.2 0.0 7.2e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CBZ29283.1 - 0.014 15.2 0.4 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 Peptidase_M1 PF01433.15 CBZ29284.1 - 1.7e-15 57.0 0.0 6.2e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M1 Peptidase_MA_2 PF13485.1 CBZ29284.1 - 1.2e-06 28.6 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF3633 PF12315.3 CBZ29284.1 - 0.0083 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3633) DUF3209 PF11483.3 CBZ29285.1 - 0.025 14.8 0.4 0.14 12.5 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3209) MOR2-PAG1_N PF14222.1 CBZ29285.1 - 0.15 10.7 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Arf PF00025.16 CBZ29286.1 - 7.8e-75 249.9 0.2 8.9e-75 249.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBZ29286.1 - 3.6e-14 52.4 0.0 4.3e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBZ29286.1 - 1.5e-13 50.4 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBZ29286.1 - 7.1e-11 41.4 0.2 4e-08 32.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CBZ29286.1 - 2.1e-09 37.9 0.0 2.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CBZ29286.1 - 7.8e-08 31.7 0.0 9.7e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ29286.1 - 1.2e-05 25.2 0.1 2e-05 24.5 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CBZ29286.1 - 0.00082 18.5 0.1 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CBZ29286.1 - 0.0011 18.4 0.1 0.014 14.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CBZ29286.1 - 0.014 15.3 0.2 0.017 14.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CBZ29286.1 - 0.14 12.0 0.5 3.8 7.4 0.0 2.1 1 1 0 2 2 2 0 AAA domain PEMT PF04191.8 CBZ29287.1 - 1.8e-30 105.1 2.5 4.5e-30 103.8 1.7 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF2198 PF09964.4 CBZ29287.1 - 0.37 10.5 3.1 9.4 6.0 0.6 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) S1-P1_nuclease PF02265.11 CBZ29289.1 - 2e-60 204.5 0.0 2.5e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF2937 PF11157.3 CBZ29289.1 - 0.0083 15.4 0.1 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2937) Zn_dep_PLPC PF00882.13 CBZ29289.1 - 0.043 13.4 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Zinc dependent phospholipase C Tetraspannin PF00335.15 CBZ29289.1 - 0.05 12.8 0.2 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Tetraspanin family TM_helix PF05552.7 CBZ29289.1 - 0.38 10.4 5.9 1.2 8.8 2.1 2.5 2 0 0 2 2 2 0 Conserved TM helix SNF2_N PF00176.18 CBZ29290.1 - 1.4e-47 161.9 0.0 2.9e-47 160.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CBZ29290.1 - 1.3e-09 37.7 0.0 8.4e-09 35.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ29290.1 - 1.5e-06 28.1 0.0 8.8e-06 25.6 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 CBZ29290.1 - 0.00015 20.6 0.0 0.014 14.1 0.0 2.3 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 CBZ29290.1 - 0.009 16.1 0.3 0.14 12.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain CATSPERD PF15020.1 CBZ29290.1 - 0.72 7.7 0.0 0.99 7.3 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta ECH PF00378.15 CBZ29291.1 - 6.1e-45 153.2 0.0 7.9e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 CBZ29291.1 - 0.085 12.6 1.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 Hydrolase_6 PF13344.1 CBZ29292.1 - 1.8e-20 72.6 0.0 9.3e-20 70.4 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBZ29292.1 - 2.2e-16 59.2 0.0 6.3e-16 57.8 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 CBZ29292.1 - 2.4e-06 28.1 0.0 0.013 15.8 0.0 2.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBZ29292.1 - 5.3e-06 26.7 0.0 0.01 16.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 CBZ29292.1 - 2.3e-05 23.8 0.0 6.9e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Symplekin_C PF12295.3 CBZ29293.1 - 2.4e-10 40.6 0.8 9.5e-09 35.4 0.0 2.9 3 0 0 3 3 3 2 Symplekin tight junction protein C terminal WD40 PF00400.27 CBZ29295.1 - 1.3e-08 34.3 0.7 0.067 13.1 0.0 4.1 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF4189 PF13827.1 CBZ29295.1 - 0.018 15.2 2.8 0.019 15.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4189) Cation_efflux PF01545.16 CBZ29297.1 - 3.9e-55 186.9 12.5 5e-55 186.5 8.7 1.1 1 0 0 1 1 1 1 Cation efflux family Phenol_monoox PF04663.7 CBZ29299.1 - 0.033 13.9 0.1 6.1 6.6 0.0 3.1 3 0 0 3 3 3 0 Phenol hydroxylase conserved region Lipase_3 PF01764.20 CBZ29304.1 - 9.1e-37 125.8 0.0 1.6e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 CBZ29304.1 - 0.00018 20.9 0.3 0.00074 18.9 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 CBZ29304.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ29304.1 - 0.036 13.9 0.0 0.046 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CBZ29304.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Fer2 PF00111.22 CBZ29307.1 - 6.1e-11 41.9 1.4 8.1e-11 41.5 1.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 CBZ29308.1 - 1.5e-10 40.7 2.0 2e-10 40.2 1.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain P12 PF12669.2 CBZ29308.1 - 0.028 14.6 0.4 0.047 13.8 0.3 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family NifU PF01106.12 CBZ29308.1 - 0.048 13.4 0.5 0.094 12.5 0.4 1.5 1 0 0 1 1 1 0 NifU-like domain Fer2 PF00111.22 CBZ29309.1 - 7.8e-10 38.3 1.4 1.1e-09 37.9 0.9 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 CBZ29310.1 - 3e-07 30.0 4.3 6e-07 29.1 3.0 1.5 1 1 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF1699 PF08004.6 CBZ29315.1 - 0.31 10.5 0.0 0.85 9.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) UCR_hinge PF02320.11 CBZ29316.1 - 5e-21 74.4 5.0 8.5e-21 73.6 3.3 1.4 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein TerD PF02342.13 CBZ29317.1 - 5.2e-78 260.6 0.1 4.6e-56 189.0 0.0 2.4 2 0 0 2 2 2 2 TerD domain Calreticulin PF00262.13 CBZ29318.1 - 1.1e-104 350.0 6.7 1.1e-104 350.0 4.7 1.6 2 0 0 2 2 2 1 Calreticulin family Laminin_G_3 PF13385.1 CBZ29318.1 - 0.033 14.4 0.4 0.071 13.3 0.3 1.6 1 1 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily RNA_pol_Rpb1_5 PF04998.12 CBZ29319.1 - 1.6e-104 349.0 0.3 2.9e-104 348.1 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CBZ29319.1 - 3.9e-95 318.9 0.1 2.1e-94 316.5 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CBZ29319.1 - 1.8e-65 219.9 0.2 5.4e-65 218.3 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CBZ29319.1 - 1.9e-44 151.6 0.8 4e-44 150.5 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 CBZ29319.1 - 1.1e-39 135.7 0.0 2.7e-39 134.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CBZ29319.1 - 4e-29 100.5 0.1 1.3e-28 98.8 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.7 CBZ29319.1 - 1e-26 93.2 0.8 3.2e-26 91.6 0.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 PspA_IM30 PF04012.7 CBZ29319.1 - 0.027 13.8 1.9 0.066 12.5 1.3 1.6 1 0 0 1 1 1 0 PspA/IM30 family CRCB PF02537.10 CBZ29320.1 - 1.1e-25 89.7 14.1 2e-19 69.6 3.6 2.5 3 0 0 3 3 3 2 CrcB-like protein OppC_N PF12911.2 CBZ29320.1 - 0.12 11.7 0.7 0.28 10.5 0.5 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Metallophos PF00149.23 CBZ29321.1 - 8.9e-43 146.0 0.6 1.1e-42 145.7 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pyr_redox_2 PF07992.9 CBZ29322.1 - 1.7e-25 90.0 0.0 3.5e-25 89.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ29322.1 - 3.5e-16 59.3 3.1 1.2e-13 51.2 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBZ29322.1 - 5.2e-15 55.4 1.1 1.3e-14 54.1 0.0 2.2 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_3 PF13738.1 CBZ29322.1 - 2.3e-12 47.3 0.8 9.2e-08 32.3 0.3 3.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBZ29322.1 - 1.2e-08 34.2 12.1 0.025 13.4 3.3 4.2 2 2 0 4 4 4 3 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CBZ29322.1 - 3.1e-08 33.1 0.1 3.1e-08 33.1 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBZ29322.1 - 4.2e-06 26.6 3.3 0.0031 17.4 0.3 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CBZ29322.1 - 1.7e-05 23.8 9.2 0.0007 18.5 2.3 3.2 2 1 0 2 2 2 2 FAD binding domain ThiF PF00899.16 CBZ29322.1 - 2.2e-05 24.2 0.2 0.00019 21.2 0.0 2.3 2 0 0 2 2 2 1 ThiF family K_oxygenase PF13434.1 CBZ29322.1 - 3e-05 23.0 0.0 0.00095 18.1 0.0 2.3 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 CBZ29322.1 - 0.00011 21.9 0.1 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 CBZ29322.1 - 0.00022 19.8 9.9 0.019 13.4 1.5 3.4 3 1 0 3 3 3 2 HI0933-like protein Lycopene_cycl PF05834.7 CBZ29322.1 - 0.00029 19.8 0.0 0.19 10.6 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 CBZ29322.1 - 0.0006 18.7 5.4 0.23 10.3 0.0 3.1 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 CBZ29322.1 - 0.0038 17.0 1.6 0.6 9.8 0.2 3.6 2 2 1 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 CBZ29322.1 - 0.0072 15.4 1.5 0.078 12.0 0.2 2.3 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 CBZ29322.1 - 0.022 14.2 0.0 0.081 12.3 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 CBZ29322.1 - 0.042 13.9 0.0 0.16 12.0 0.0 2.0 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 CBZ29322.1 - 0.089 11.8 7.3 0.23 10.4 1.6 2.5 2 1 0 2 2 2 0 FAD binding domain BTD PF09270.5 CBZ29322.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.6 2 0 0 2 2 2 0 Beta-trefoil DNA-binding domain TrkA_N PF02254.13 CBZ29322.1 - 0.25 11.3 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 CBZ29323.1 - 8.6e-30 104.1 0.0 1.1e-29 103.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBZ29323.1 - 9.8e-20 70.6 0.5 4.2e-19 68.6 0.0 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBZ29323.1 - 5.9e-17 61.8 1.3 1.1e-12 48.2 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CBZ29323.1 - 6.2e-11 42.0 0.1 6.2e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CBZ29323.1 - 7.4e-10 39.2 0.1 2.8e-09 37.3 0.0 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ29323.1 - 1.4e-08 34.6 2.5 8.7e-05 22.4 0.3 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CBZ29323.1 - 1.6e-08 33.8 1.8 1.2e-06 27.6 0.2 2.8 2 1 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 CBZ29323.1 - 1.2e-07 30.9 6.1 6.5e-06 25.2 0.2 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 CBZ29323.1 - 1.4e-06 27.0 2.7 7e-06 24.7 0.2 2.7 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 CBZ29323.1 - 1.4e-06 27.6 0.7 0.00029 19.9 0.0 2.7 3 0 0 3 3 3 1 Thi4 family Lycopene_cycl PF05834.7 CBZ29323.1 - 1.8e-06 27.1 0.6 0.00062 18.7 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 CBZ29323.1 - 2.1e-06 26.8 0.6 2.1e-06 26.8 0.4 2.5 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 CBZ29323.1 - 9.1e-06 24.9 1.2 0.0033 16.5 0.0 3.0 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 CBZ29323.1 - 0.0026 16.7 0.1 0.05 12.5 0.0 2.3 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.13 CBZ29323.1 - 0.0031 17.4 2.8 0.11 12.5 0.2 3.1 3 0 0 3 3 3 1 TrkA-N domain ThiF PF00899.16 CBZ29323.1 - 0.0044 16.8 0.3 0.027 14.3 0.1 2.4 2 0 0 2 2 2 1 ThiF family NAD_binding_9 PF13454.1 CBZ29323.1 - 0.0071 16.1 0.7 0.072 12.8 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 CBZ29323.1 - 0.06 13.0 0.4 22 4.7 0.0 3.1 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 CBZ29323.1 - 0.18 12.0 1.0 1.6 9.0 0.1 2.8 3 1 0 3 3 3 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 CBZ29323.1 - 0.59 9.7 5.2 1.8 8.1 0.1 3.4 4 1 0 4 4 4 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Plasmodium_Vir PF05795.6 CBZ29326.1 - 0.37 9.9 1.3 0.64 9.1 0.9 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PPR PF01535.15 CBZ29328.1 - 0.054 13.4 0.1 4.8 7.3 0.0 2.8 2 0 0 2 2 2 0 PPR repeat DNA_pol_A_exo1 PF01612.15 CBZ29329.1 - 8.2e-06 25.4 0.0 3.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 3'-5' exonuclease MORN PF02493.15 CBZ29330.1 - 5.3e-31 104.4 45.6 5.8e-09 35.1 0.5 7.7 7 0 0 7 7 7 7 MORN repeat Kinesin PF00225.18 CBZ29330.1 - 1.8e-19 69.6 0.4 7.6e-19 67.5 0.0 2.1 2 1 0 2 2 2 1 Kinesin motor domain Seadorna_VP6 PF07407.6 CBZ29330.1 - 0.35 9.5 1.0 0.76 8.4 0.7 1.5 1 0 0 1 1 1 0 Seadornavirus VP6 protein Reo_sigmaC PF04582.7 CBZ29330.1 - 0.59 9.2 5.7 0.74 8.9 0.5 3.1 2 1 0 3 3 3 0 Reovirus sigma C capsid protein Bap31 PF05529.7 CBZ29331.1 - 0.0042 16.5 3.2 0.0064 15.9 2.2 1.4 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF2238 PF09997.4 CBZ29331.1 - 0.062 12.6 1.5 0.24 10.7 0.4 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2238) RCC1 PF00415.13 CBZ29332.1 - 2.4e-25 88.4 5.7 3.4e-11 43.1 0.0 7.3 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ29332.1 - 5e-19 67.4 17.1 3.1e-05 23.4 1.2 5.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.1 CBZ29332.1 - 0.017 15.2 0.0 4.9 7.3 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4213) EMP24_GP25L PF01105.19 CBZ29333.1 - 6e-30 104.3 0.0 8.1e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD COPIIcoated_ERV PF07970.7 CBZ29334.1 - 5.6e-65 219.0 0.0 9.2e-65 218.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CBZ29334.1 - 3e-29 100.8 0.3 3e-29 100.8 0.2 1.9 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) FH2 PF02181.18 CBZ29335.1 - 0.12 11.2 1.8 0.19 10.5 1.2 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain IncA PF04156.9 CBZ29335.1 - 0.34 10.4 11.8 0.55 9.8 8.2 1.3 1 0 0 1 1 1 0 IncA protein SYCE1 PF15233.1 CBZ29335.1 - 3.7 7.4 11.3 6 6.8 7.8 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 APG6 PF04111.7 CBZ29335.1 - 5.2 6.0 15.1 0.58 9.1 5.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 HNF-1_N PF04814.8 CBZ29336.1 - 0.22 11.5 4.9 0.49 10.4 0.9 2.5 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus RRM_1 PF00076.17 CBZ29337.1 - 1.6e-11 43.6 0.0 3.3e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ29337.1 - 0.00083 19.2 0.0 0.0031 17.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ29337.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 CBZ29338.1 - 0.86 7.7 12.1 1.1 7.3 8.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Arf PF00025.16 CBZ29339.1 - 2.2e-77 258.2 0.2 2.4e-77 258.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CBZ29339.1 - 2.5e-14 52.8 0.0 3e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CBZ29339.1 - 8.5e-13 48.0 0.0 9.2e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CBZ29339.1 - 2.2e-12 46.3 0.5 8e-09 34.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBZ29339.1 - 1e-09 37.9 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CBZ29339.1 - 2.5e-08 34.4 0.0 3.3e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBZ29339.1 - 4.8e-05 23.2 0.1 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CBZ29339.1 - 0.0062 15.6 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 CBZ29339.1 - 0.0097 15.3 0.1 0.11 11.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CBZ29339.1 - 0.039 13.8 0.1 0.06 13.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 CBZ29339.1 - 0.061 12.7 0.2 0.46 9.9 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PGC7_Stella PF15549.1 CBZ29340.1 - 1 9.3 6.5 1.6 8.7 4.5 1.2 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain DUF1771 PF08590.5 CBZ29341.1 - 1.4e-18 66.6 6.8 1.4e-18 66.6 4.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 CBZ29341.1 - 5.8e-12 45.6 0.0 1.7e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Smr domain KH_1 PF00013.24 CBZ29341.1 - 7.2e-10 38.3 0.4 1.2e-09 37.6 0.3 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CBZ29341.1 - 1.2e-05 24.8 0.2 2.2e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CBZ29341.1 - 0.0034 16.9 0.5 0.0092 15.5 0.1 1.9 2 0 0 2 2 2 1 KH domain Maf1 PF09174.5 CBZ29342.1 - 5.1e-44 150.2 0.0 6e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Maf1 regulator Tryp_alpha_amyl PF00234.17 CBZ29342.1 - 0.038 14.2 0.0 0.061 13.5 0.0 1.3 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family GILT PF03227.11 CBZ29342.1 - 0.098 12.5 0.8 4.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF948 PF06103.6 CBZ29344.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF1049 PF06305.6 CBZ29344.1 - 1.8 8.1 5.1 0.2 11.1 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Ribosomal_L12 PF00542.14 CBZ29345.1 - 6.7e-18 64.4 1.7 1.2e-17 63.6 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain MerR_1 PF13411.1 CBZ29345.1 - 0.054 13.2 0.1 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein PYRIN PF02758.11 CBZ29345.1 - 0.068 12.8 0.1 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain Ribosomal_60s PF00428.14 CBZ29345.1 - 3.6 8.0 15.5 6.2 7.2 9.8 2.1 1 1 0 1 1 1 0 60s Acidic ribosomal protein Pkinase PF00069.20 CBZ29346.1 - 7.5e-56 189.1 0.0 2.4e-55 187.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29346.1 - 2.9e-29 101.9 0.0 6.1e-29 100.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 CBZ29346.1 - 0.01 15.1 0.2 0.051 12.9 0.1 2.2 1 1 0 1 1 1 0 RIO1 family L71 PF02448.10 CBZ29346.1 - 0.012 15.3 0.2 0.032 14.0 0.1 1.7 1 0 0 1 1 1 0 L71 family Spc7 PF08317.6 CBZ29346.1 - 0.022 13.4 0.5 0.022 13.4 0.4 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Pox_ser-thr_kin PF05445.6 CBZ29346.1 - 0.028 13.2 0.1 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Spc42p PF11544.3 CBZ29346.1 - 0.4 10.6 3.9 1 9.3 0.5 2.7 2 0 0 2 2 2 0 Spindle pole body component Spc42p Fib_alpha PF08702.5 CBZ29346.1 - 1.7 8.7 6.3 9.4 6.3 0.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 CBZ29346.1 - 4 6.9 11.1 1.1 8.7 0.0 3.3 3 0 0 3 3 3 0 Septum formation initiator Bap31 PF05529.7 CBZ29346.1 - 4.4 6.7 7.3 7 6.0 0.1 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Aldo_ket_red PF00248.16 CBZ29348.1 - 1.8e-64 217.2 0.0 2.1e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 CBZ29348.1 - 0.055 13.6 0.0 0.09 12.9 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Clathrin PF00637.15 CBZ29349.1 - 1e-10 41.3 0.7 4.8e-10 39.1 0.2 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 CBZ29349.1 - 0.032 14.0 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal zf-Apc11 PF12861.2 CBZ29349.1 - 0.068 13.0 2.9 0.33 10.8 2.0 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBZ29349.1 - 0.2 11.7 5.4 0.56 10.3 3.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 CBZ29349.1 - 0.72 9.7 12.3 0.74 9.6 6.8 2.5 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 CBZ29349.1 - 1.1 9.0 14.9 0.56 9.9 7.1 2.7 2 0 0 2 2 2 0 zinc-RING finger domain DUF2396 PF09654.5 CBZ29349.1 - 2.8 7.8 5.8 0.2 11.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) zf-C3HC4_2 PF13923.1 CBZ29349.1 - 7.7 6.6 12.5 1.9 8.5 5.5 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Nup54 PF13874.1 CBZ29350.1 - 8.8e-40 135.6 0.2 8.8e-40 135.6 0.1 1.9 2 1 0 2 2 2 1 Nucleoporin complex subunit 54 MBD_C PF14048.1 CBZ29350.1 - 0.014 15.9 0.2 0.17 12.5 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF4618 PF15397.1 CBZ29350.1 - 0.6 9.3 6.6 4.9 6.4 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF4588 PF15251.1 CBZ29352.1 - 0.00087 19.3 1.0 0.002 18.1 0.1 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4588) Hairy_orange PF07527.8 CBZ29352.1 - 0.025 14.3 0.1 0.067 12.9 0.1 1.8 1 1 0 1 1 1 0 Hairy Orange Inositol_P PF00459.20 CBZ29353.1 - 1.9e-13 50.3 0.4 1.7e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 Inositol monophosphatase family Ribosomal_L7Ae PF01248.21 CBZ29354.1 - 0.011 15.1 0.1 0.024 14.1 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SQS_PSY PF00494.14 CBZ29355.1 - 3.3e-44 151.2 0.0 4.8e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase NUDIX PF00293.23 CBZ29356.1 - 5.1e-14 52.0 0.1 8.5e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 CBZ29356.1 - 4.1e-10 38.9 3.5 6.9e-10 38.2 2.5 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 CBZ29356.1 - 0.00011 21.2 5.2 0.00029 19.9 3.6 1.7 1 1 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 CBZ29356.1 - 0.0012 18.6 2.5 0.003 17.3 1.7 1.6 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 CBZ29356.1 - 0.0013 18.1 4.6 0.31 10.6 0.2 2.4 2 0 0 2 2 2 2 zinc-ribbon domain NOB1_Zn_bind PF08772.6 CBZ29356.1 - 0.0046 16.7 0.1 2.9 7.7 0.0 2.4 2 0 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like OrfB_Zn_ribbon PF07282.6 CBZ29356.1 - 0.006 16.2 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Nudix_N_2 PF14803.1 CBZ29356.1 - 0.024 14.3 2.4 3.1 7.5 0.2 2.4 2 0 0 2 2 2 0 Nudix N-terminal HypA PF01155.14 CBZ29356.1 - 0.033 13.8 0.1 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 CBZ29356.1 - 0.14 11.9 6.3 3.6 7.3 0.4 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DUF35_N PF12172.3 CBZ29356.1 - 0.73 9.8 5.0 2.1 8.3 0.6 2.5 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pkinase PF00069.20 CBZ29357.1 - 4e-63 212.9 0.0 5.3e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29357.1 - 1.1e-43 149.1 0.0 1.7e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ29357.1 - 6.7e-09 35.1 0.0 4.2e-07 29.2 0.0 2.6 3 0 0 3 3 3 1 Kinase-like PH PF00169.24 CBZ29357.1 - 3.9e-05 23.8 0.0 7.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PH domain DUF1636 PF07845.6 CBZ29357.1 - 0.051 13.8 0.4 0.12 12.5 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1636) Kdo PF06293.9 CBZ29357.1 - 0.15 11.1 0.1 0.7 8.9 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Carboxyl_trans PF01039.17 CBZ29358.1 - 1.3e-126 422.8 0.0 1.8e-126 422.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.7 CBZ29358.1 - 2.1e-115 386.4 0.0 3.7e-108 362.5 0.1 2.1 1 1 1 2 2 2 2 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.12 CBZ29358.1 - 1.7e-51 174.4 0.0 4.3e-51 173.2 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBZ29358.1 - 2.8e-25 88.5 0.0 1.4e-24 86.3 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBZ29358.1 - 1.6e-21 76.2 0.0 1.2e-20 73.5 0.0 2.5 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain ATPgrasp_Ter PF15632.1 CBZ29358.1 - 2.4e-12 46.2 0.0 2.7e-11 42.7 0.0 2.4 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CBZ29358.1 - 8.2e-11 41.9 0.0 1.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CBZ29358.1 - 2.5e-07 30.2 0.0 6.3e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CBZ29358.1 - 1.3e-06 27.9 0.0 2.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBZ29358.1 - 0.0001 21.7 0.2 0.00035 19.9 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CBZ29358.1 - 0.001 18.9 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CBZ29358.1 - 0.076 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like nsp9 PF08710.5 CBZ29358.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 nsp9 replicase ATPgrasp_ST PF14397.1 CBZ29358.1 - 0.38 9.8 0.0 0.71 8.9 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RimK PF08443.6 CBZ29358.1 - 0.53 9.7 0.0 4.5 6.6 0.0 2.1 1 1 0 1 1 1 0 RimK-like ATP-grasp domain SMK-1 PF04802.10 CBZ29359.1 - 4.1e-06 26.4 0.0 6.8e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 TilS PF09179.6 CBZ29359.1 - 0.023 14.7 0.4 0.062 13.3 0.0 1.9 2 0 0 2 2 2 0 TilS substrate binding domain DUF3573 PF12097.3 CBZ29360.1 - 0.75 8.3 0.1 1.9 7.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Spc7 PF08317.6 CBZ29362.1 - 0.03 12.9 5.8 0.012 14.3 2.3 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein CENP-H PF05837.7 CBZ29362.1 - 0.076 13.1 4.0 0.24 11.6 2.8 1.9 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FlaC_arch PF05377.6 CBZ29362.1 - 0.2 11.5 0.3 28 4.7 0.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Cep57_MT_bd PF06657.8 CBZ29362.1 - 0.97 9.4 8.0 0.68 9.9 2.3 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Transposase_22 PF02994.9 CBZ29366.1 - 0.01 14.3 0.1 0.019 13.5 0.1 1.3 1 0 0 1 1 1 0 L1 transposable element Per1 PF04080.8 CBZ29366.1 - 0.012 15.0 0.1 0.014 14.8 0.1 1.1 1 0 0 1 1 1 0 Per1-like DUF1515 PF07439.6 CBZ29366.1 - 0.08 12.7 4.5 0.46 10.3 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF948 PF06103.6 CBZ29366.1 - 0.11 12.3 2.4 0.33 10.8 1.5 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Cyclase PF04199.8 CBZ29367.1 - 1.7e-17 63.6 0.0 2.2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase Zip PF02535.17 CBZ29368.1 - 1.4e-42 145.7 2.6 1.7e-42 145.5 1.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.17 CBZ29369.1 - 4e-42 144.3 2.5 4.7e-42 144.1 1.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter BTB_2 PF02214.17 CBZ29370.1 - 8.3e-05 22.7 0.0 0.00024 21.2 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain SPRY PF00622.23 CBZ29370.1 - 0.00013 22.0 0.0 0.014 15.4 0.0 2.6 2 1 1 3 3 3 2 SPRY domain Peptidase_M16 PF00675.15 CBZ29371.1 - 1.1e-31 109.5 0.0 2.4e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBZ29371.1 - 4.2e-11 42.8 0.0 6e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain DnaJ PF00226.26 CBZ29372.1 - 3.8e-19 68.1 0.1 6.1e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3667 PF12412.3 CBZ29372.1 - 0.09 12.0 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) Lzipper-MIP1 PF14389.1 CBZ29374.1 - 0.06 13.4 0.3 0.06 13.4 0.2 8.8 9 0 0 9 9 9 0 Leucine-zipper of ternary complex factor MIP1 Corona_M PF01635.13 CBZ29374.1 - 0.2 10.5 0.0 0.36 9.7 0.0 1.4 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein SUV3_C PF12513.3 CBZ29374.1 - 0.6 9.5 5.4 0.97 8.9 0.3 3.4 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal PEMT PF04191.8 CBZ29375.1 - 1.2e-49 166.7 11.9 3.6e-28 97.7 0.7 2.9 2 0 0 2 2 2 2 Phospholipid methyltransferase CPSase_L_D2 PF02786.12 CBZ29376.1 - 8.4e-63 211.4 0.0 1.4e-62 210.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CBZ29376.1 - 1.9e-41 140.5 0.1 7.3e-41 138.7 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CBZ29376.1 - 1.1e-33 115.4 0.0 2.4e-33 114.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CBZ29376.1 - 2.9e-15 55.6 2.2 5.8e-15 54.7 1.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CBZ29376.1 - 5.9e-15 55.4 0.1 1.2e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBZ29376.1 - 1.9e-11 43.3 0.0 4.7e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CBZ29376.1 - 2.4e-11 43.3 0.0 8e-11 41.6 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CBZ29376.1 - 7.7e-09 35.1 0.1 1.4e-08 34.2 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 CBZ29376.1 - 5.2e-06 25.8 0.3 0.008 15.3 0.1 2.2 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 CBZ29376.1 - 2.7e-05 23.7 0.2 0.00012 21.6 0.0 2.0 1 1 1 2 2 2 1 Biotin-lipoyl like RimK PF08443.6 CBZ29376.1 - 0.0069 15.8 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CBZ29376.1 - 0.0094 15.8 0.0 0.029 14.2 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 CBZ29376.1 - 0.13 11.5 0.1 0.29 10.3 0.0 1.6 1 1 1 2 2 2 0 HlyD family secretion protein HlyD_3 PF13437.1 CBZ29376.1 - 0.15 12.4 0.4 24 5.3 0.0 2.8 3 0 0 3 3 3 0 HlyD family secretion protein Robl_LC7 PF03259.12 CBZ29378.1 - 5.6e-09 35.4 0.0 7.9e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Roadblock/LC7 domain PQQ_2 PF13360.1 CBZ29379.1 - 0.0011 18.4 0.1 2 7.8 0.0 4.1 3 1 0 3 3 3 1 PQQ-like domain Fib_alpha PF08702.5 CBZ29379.1 - 4.4 7.4 12.0 2.7 8.1 0.9 3.6 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Herpes_UL25 PF01499.11 CBZ29379.1 - 4.5 5.4 18.7 0.012 13.9 3.4 2.7 3 0 0 3 3 3 0 Herpesvirus UL25 family Pkinase PF00069.20 CBZ29380.1 - 4.1e-61 206.4 0.0 5.6e-61 205.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29380.1 - 3.1e-41 141.1 0.0 4.3e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CBZ29380.1 - 2.1e-10 40.7 0.0 3.5e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 CBZ29380.1 - 1.9e-08 34.5 0.3 5.4e-07 29.7 0.2 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 CBZ29380.1 - 2.1e-08 33.4 0.0 3.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 CBZ29380.1 - 0.00013 22.1 1.3 0.037 14.2 0.9 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain MFS_1 PF07690.11 CBZ29381.1 - 1.9e-23 82.7 35.2 2.9e-20 72.3 15.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CBZ29381.1 - 4.2e-09 36.0 16.2 4.2e-09 36.0 11.2 2.7 2 2 0 2 2 2 1 Nodulin-like Histone PF00125.19 CBZ29382.1 - 1.1e-13 51.1 0.7 1.3e-13 50.8 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ29382.1 - 6.6e-05 22.8 0.8 7.1e-05 22.7 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CBZ29382.1 - 0.0003 20.6 0.2 0.00048 20.0 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CBZ29382.1 - 0.00065 19.3 0.0 0.00083 19.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CBZ29382.1 - 0.0016 18.1 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 CBZ29382.1 - 0.086 12.7 1.0 0.17 11.7 0.2 2.0 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit FbpA PF05833.6 CBZ29382.1 - 0.086 11.3 0.0 0.1 11.1 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Galactosyl_T PF01762.16 CBZ29383.1 - 0.00036 20.1 1.1 0.00072 19.2 0.0 2.0 3 0 0 3 3 3 1 Galactosyltransferase WXG100 PF06013.7 CBZ29385.1 - 5.9 6.9 9.6 1.5 8.8 0.7 3.7 4 0 0 4 4 4 0 Proteins of 100 residues with WXG WD40 PF00400.27 CBZ29388.1 - 6.3e-39 130.4 5.3 2.5e-08 33.5 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat SNARE PF05739.14 CBZ29390.1 - 9.9e-14 50.7 8.5 1.2e-13 50.5 1.1 3.1 3 0 0 3 3 3 1 SNARE domain DUF4208 PF13907.1 CBZ29390.1 - 0.016 15.4 1.3 2.6 8.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) DUF1640 PF07798.6 CBZ29390.1 - 0.084 12.9 4.6 0.86 9.6 3.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF3154 PF11351.3 CBZ29390.1 - 0.56 9.9 5.0 1.6 8.4 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3154) DUF2422 PF10337.4 CBZ29390.1 - 1.2 7.8 5.8 2 7.1 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Baculo_PEP_C PF04513.7 CBZ29390.1 - 1.3 8.8 8.6 2.8 7.7 0.8 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 CBZ29390.1 - 3.3 7.8 11.1 38 4.3 0.2 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF883 PF05957.8 CBZ29390.1 - 3.7 8.0 10.5 0.43 11.0 1.0 3.1 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) NMT_C PF02799.10 CBZ29391.1 - 5.8e-72 241.0 0.6 9e-72 240.4 0.1 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 CBZ29391.1 - 4.5e-63 211.6 0.9 9.3e-61 204.1 0.6 2.3 1 1 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NIF PF03031.13 CBZ29393.1 - 3.4e-25 88.5 0.0 3.7e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mito_carr PF00153.22 CBZ29394.1 - 2.9e-40 135.8 4.2 1.1e-13 50.6 0.0 4.4 3 2 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 CBZ29395.1 - 1.2e-58 198.3 0.0 1.5e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29395.1 - 9.8e-28 96.9 0.0 1.4e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ29395.1 - 0.00021 20.3 0.0 0.00039 19.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBZ29395.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ29395.1 - 0.077 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Skp1 PF01466.14 CBZ29396.1 - 0.049 13.6 0.2 0.084 12.9 0.1 1.3 1 0 0 1 1 1 0 Skp1 family, dimerisation domain Arm PF00514.18 CBZ29397.1 - 2.7e-44 147.5 22.1 1.8e-07 30.7 0.0 16.6 16 1 0 16 16 16 9 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 CBZ29397.1 - 7.2e-09 35.1 1.0 0.066 12.3 0.0 6.2 4 2 3 8 8 8 2 Armadillo-like HEAT_2 PF13646.1 CBZ29397.1 - 1.2e-06 28.7 7.1 0.19 12.0 0.0 6.4 4 3 3 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 CBZ29397.1 - 0.00015 22.1 9.0 2.6 8.6 0.1 7.6 6 2 1 7 7 7 1 HEAT-like repeat Atx10homo_assoc PF09759.4 CBZ29397.1 - 0.048 13.3 1.7 14 5.4 0.0 4.8 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.17 CBZ29397.1 - 0.11 12.6 12.4 44 4.5 0.1 7.0 6 1 0 6 6 6 0 HEAT repeat TMF_DNA_bd PF12329.3 CBZ29397.1 - 0.55 10.0 7.3 1.3 8.8 5.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Utp14 PF04615.8 CBZ29398.1 - 1.5e-80 271.4 41.0 1.6e-80 271.2 27.6 1.6 1 1 0 1 1 1 1 Utp14 protein Mit_KHE1 PF10173.4 CBZ29398.1 - 0.026 14.3 0.4 0.072 12.9 0.3 1.8 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related LRR_9 PF14580.1 CBZ29401.1 - 2.6e-17 62.9 1.2 6.8e-17 61.5 0.8 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CBZ29401.1 - 0.00057 19.4 0.7 0.29 10.8 0.0 3.3 2 2 1 3 3 3 1 Leucine Rich repeats (2 copies) CCDC-167 PF15188.1 CBZ29401.1 - 0.017 15.0 3.1 0.017 15.0 2.2 2.3 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF4404 PF14357.1 CBZ29401.1 - 5.2 7.5 7.7 2.7 8.4 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) HSP70 PF00012.15 CBZ29403.1 - 7.4e-08 30.7 0.1 0.00059 17.8 0.0 3.1 4 0 0 4 4 4 2 Hsp70 protein Baculo_PEP_C PF04513.7 CBZ29404.1 - 0.4 10.5 5.4 14 5.4 0.0 3.5 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 CBZ29404.1 - 1.3 8.3 11.2 30 3.9 7.7 2.8 1 1 0 1 1 1 0 Intermediate filament protein Rtt106 PF08512.7 CBZ29405.1 - 6.8e-15 54.8 0.0 5.9e-14 51.8 0.0 2.6 4 0 0 4 4 4 1 Histone chaperone Rttp106-like SSrecog PF03531.9 CBZ29405.1 - 1.6e-05 24.3 0.1 0.19 11.0 0.0 2.8 2 1 0 2 2 2 2 Structure-specific recognition protein (SSRP1) YL1 PF05764.8 CBZ29405.1 - 0.02 14.5 38.0 0.028 14.0 26.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.9 CBZ29405.1 - 0.39 8.7 29.5 0.62 8.0 20.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Herpes_DNAp_acc PF04929.7 CBZ29405.1 - 0.67 8.8 12.4 1 8.2 8.6 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Nop14 PF04147.7 CBZ29405.1 - 0.86 7.4 32.4 1.1 7.0 22.4 1.1 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.4 CBZ29405.1 - 9.6 4.9 21.0 14 4.4 14.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dynein_light PF01221.13 CBZ29407.1 - 3.4e-43 145.5 0.9 3.9e-43 145.3 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.15 CBZ29407.1 - 0.00056 19.7 0.1 0.00058 19.7 0.0 1.1 1 0 0 1 1 1 1 3C cysteine protease (picornain 3C) HTH_33 PF13592.1 CBZ29407.1 - 0.053 13.0 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Imm28 PF15574.1 CBZ29407.1 - 0.054 13.0 0.1 0.072 12.6 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 28 Ectatomin PF06457.6 CBZ29407.1 - 0.055 13.1 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Ectatomin ECSIT PF06239.6 CBZ29407.1 - 0.1 11.4 0.1 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway LRR_6 PF13516.1 CBZ29408.1 - 0.00048 19.9 0.9 5.5 7.3 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 CBZ29408.1 - 0.00052 19.5 2.8 4.4 7.0 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ29408.1 - 0.019 14.9 6.9 9.5 6.7 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat AAA_13 PF13166.1 CBZ29408.1 - 0.14 10.6 1.7 0.22 9.9 1.2 1.2 1 0 0 1 1 1 0 AAA domain LRR_8 PF13855.1 CBZ29408.1 - 0.26 11.0 2.4 8 6.2 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 CBZ29408.1 - 0.35 11.2 6.2 14 6.4 0.3 3.9 4 0 0 4 4 4 0 Leucine rich repeat Atg14 PF10186.4 CBZ29408.1 - 0.81 8.5 15.1 0.16 10.8 7.7 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Cluap1 PF10234.4 CBZ29408.1 - 5.5 6.1 12.6 0.62 9.2 4.8 2.0 1 1 1 2 2 2 0 Clusterin-associated protein-1 Pkinase PF00069.20 CBZ29410.1 - 9.1e-71 238.0 0.0 1.4e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29410.1 - 8.6e-51 172.4 0.0 1.2e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ29410.1 - 3e-06 26.4 0.0 6.5e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBZ29410.1 - 0.021 14.1 0.1 0.05 12.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family B9-C2 PF07162.6 CBZ29412.1 - 9.3e-45 152.4 0.0 1.1e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein LRR_4 PF12799.2 CBZ29414.1 - 2.4e-16 58.9 1.8 0.00037 20.0 0.3 5.3 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ29414.1 - 1e-09 37.9 5.7 0.00095 18.8 1.0 4.5 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CBZ29414.1 - 3.7e-08 32.2 8.4 0.047 13.7 0.2 6.8 6 1 0 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ29414.1 - 0.0043 16.9 5.3 0.23 11.8 0.1 5.0 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 CBZ29414.1 - 0.007 16.3 1.6 49 4.4 0.1 5.0 4 1 1 5 5 5 0 Leucine Rich repeat Coatomer_WDAD PF04053.9 CBZ29415.1 - 1.4e-05 24.1 3.7 0.013 14.2 0.0 4.2 4 1 1 5 5 5 1 Coatomer WD associated region TPR_19 PF14559.1 CBZ29415.1 - 3.3e-05 24.1 22.8 0.014 15.6 0.2 7.8 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ29415.1 - 3.7e-05 23.2 17.8 0.99 9.3 0.4 7.8 7 1 1 8 8 8 3 Tetratricopeptide repeat Clathrin PF00637.15 CBZ29415.1 - 8.9e-05 22.1 0.3 3.5 7.2 0.0 5.2 4 2 1 5 5 5 1 Region in Clathrin and VPS TPR_14 PF13428.1 CBZ29415.1 - 0.00097 19.5 27.1 7.2 7.5 1.2 10.7 9 1 2 11 11 9 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ29415.1 - 0.006 16.4 21.5 1.5 8.8 0.2 8.1 7 2 2 9 9 9 1 Tetratricopeptide repeat Nucleoporin_N PF08801.6 CBZ29415.1 - 0.045 12.4 0.0 0.087 11.5 0.0 1.4 1 0 0 1 1 1 0 Nup133 N terminal like WD40 PF00400.27 CBZ29415.1 - 0.21 11.5 1.3 16 5.5 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat MIT PF04212.13 CBZ29415.1 - 0.32 10.9 11.4 19 5.2 0.1 5.2 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 CBZ29415.1 - 0.46 10.1 19.5 6.5 6.5 0.1 6.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ29415.1 - 0.64 10.0 31.5 3.5 7.7 2.4 9.4 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ29415.1 - 1.7 9.4 34.9 0.27 11.9 1.2 7.9 8 1 0 8 8 7 0 Tetratricopeptide repeat RHD3 PF05879.7 CBZ29421.1 - 2.9e-105 352.8 0.0 4.8e-93 312.4 0.0 3.1 3 0 0 3 3 3 3 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 CBZ29421.1 - 2e-05 24.4 0.1 3.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.1 CBZ29421.1 - 0.00033 20.6 0.1 0.0012 18.8 0.1 2.0 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CBZ29421.1 - 0.02 15.4 0.0 0.046 14.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 CBZ29421.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase JAB PF01398.16 CBZ29423.1 - 4.2e-22 78.0 0.0 2.9e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CBZ29423.1 - 1.4e-20 73.4 0.2 2.7e-20 72.5 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF2365 PF10157.4 CBZ29423.1 - 0.0021 17.9 0.9 0.0037 17.1 0.7 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) DEAD PF00270.24 CBZ29424.1 - 1.4e-42 145.1 0.0 2.8e-42 144.1 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ29424.1 - 8.5e-27 92.8 0.1 4.6e-26 90.4 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GRIM-19 PF06212.7 CBZ29424.1 - 0.05 13.3 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 GRIM-19 protein PLRV_ORF5 PF01690.12 CBZ29424.1 - 0.77 8.8 13.1 1.3 8.1 9.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein TPR_11 PF13414.1 CBZ29425.1 - 2.7e-10 39.7 16.6 0.0021 17.6 0.5 5.8 5 0 0 5 5 5 4 TPR repeat TPR_16 PF13432.1 CBZ29425.1 - 1.4e-05 25.6 46.3 0.0022 18.5 4.7 7.6 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ29425.1 - 5.6e-05 23.0 17.1 3.6 7.6 0.1 6.8 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ29425.1 - 8.9e-05 22.7 10.2 0.089 13.1 0.8 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat HemY_N PF07219.8 CBZ29425.1 - 0.086 12.3 2.4 0.18 11.3 0.1 2.8 3 0 0 3 3 3 0 HemY protein N-terminus TPR_2 PF07719.12 CBZ29425.1 - 0.13 12.2 28.8 1.6 8.7 0.0 9.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ29425.1 - 0.14 12.0 1.7 10 6.1 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ29425.1 - 1 9.1 11.2 5.2 6.8 0.9 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Kinesin PF00225.18 CBZ29426.1 - 1e-32 113.1 0.0 1.4e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain MORN PF02493.15 CBZ29426.1 - 4.9e-18 63.6 32.9 0.00018 21.0 0.0 7.5 7 0 0 7 7 7 5 MORN repeat Ribosomal_L22 PF00237.14 CBZ29427.1 - 2.7e-30 104.4 0.2 3.3e-30 104.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1279 PF06916.8 CBZ29428.1 - 2.3e-06 27.7 0.0 3.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) WW PF00397.21 CBZ29428.1 - 0.0013 18.5 0.2 0.003 17.3 0.2 1.6 1 0 0 1 1 1 1 WW domain Fumarate_red_D PF02313.12 CBZ29428.1 - 0.038 13.8 0.6 0.057 13.3 0.1 1.5 2 0 0 2 2 2 0 Fumarate reductase subunit D Ribosomal_S5_C PF03719.10 CBZ29429.1 - 1.9e-24 84.6 0.0 3.3e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 CBZ29429.1 - 2.3e-21 75.3 0.3 3.6e-21 74.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Aldo_ket_red PF00248.16 CBZ29430.1 - 3.2e-63 213.1 0.0 3.7e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_6 PF13516.1 CBZ29431.1 - 1.2e-13 49.5 8.1 0.14 12.2 0.3 9.2 10 0 0 10 10 10 3 Leucine Rich repeat LRR_4 PF12799.2 CBZ29431.1 - 1.9e-07 30.5 2.0 11 5.7 0.0 6.9 7 1 0 7 7 7 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ29431.1 - 5.7e-05 22.5 4.6 28 5.2 0.2 8.3 10 0 0 10 10 10 0 Leucine Rich Repeat CDC45 PF02724.9 CBZ29431.1 - 0.033 12.2 18.3 0.069 11.1 12.7 1.5 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.1 CBZ29431.1 - 0.047 12.2 1.7 0.074 11.5 1.2 1.2 1 0 0 1 1 1 0 Raftlin Peptidase_S49 PF01343.13 CBZ29431.1 - 0.11 12.3 0.1 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Peptidase family S49 Nop14 PF04147.7 CBZ29431.1 - 3.8 5.2 28.0 7.3 4.3 19.4 1.3 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 CBZ29431.1 - 3.9 7.0 22.2 1.8 8.1 10.8 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region RNA_polI_A34 PF08208.6 CBZ29431.1 - 5 6.7 12.4 41 3.7 0.0 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Rtf2 PF04641.7 CBZ29432.1 - 8e-24 84.2 0.2 1.8e-23 83.1 0.1 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 CBZ29432.1 - 0.0017 17.8 0.0 1.3 8.6 0.0 2.5 2 1 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CBZ29432.1 - 0.062 13.0 0.1 0.34 10.6 0.0 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-Di19 PF05605.7 CBZ29432.1 - 3.1 7.9 4.6 0.79 9.8 0.2 2.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ras PF00071.17 CBZ29435.1 - 1.6e-56 190.1 0.1 1.8e-56 189.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ29435.1 - 2.7e-23 82.7 0.0 4.3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ29435.1 - 1.3e-14 53.8 0.0 1.5e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CBZ29435.1 - 1.6e-07 30.9 0.1 6.6e-07 28.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CBZ29435.1 - 2.8e-06 26.6 0.0 3.2e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ29435.1 - 4.8e-06 26.5 0.0 6.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 CBZ29435.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.4 CBZ29435.1 - 0.0019 17.6 0.1 0.0037 16.7 0.1 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CBZ29435.1 - 0.004 17.3 0.0 0.011 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ29435.1 - 0.0068 16.4 0.1 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.14 CBZ29435.1 - 0.01 15.2 0.0 1.8 7.9 0.0 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CBZ29435.1 - 0.011 14.9 0.0 0.021 14.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 CBZ29435.1 - 0.016 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 CBZ29435.1 - 0.034 13.7 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain YwhD PF08741.5 CBZ29435.1 - 0.04 13.3 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 YwhD family ATP_bind_1 PF03029.12 CBZ29435.1 - 0.066 12.7 0.0 2.7 7.4 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 CBZ29435.1 - 0.13 12.4 0.0 0.4 10.8 0.0 2.0 1 1 1 2 2 2 0 RNA helicase CDC50 PF03381.10 CBZ29437.1 - 9.7e-56 188.9 0.0 1.3e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Neurensin PF14927.1 CBZ29437.1 - 0.11 11.8 0.3 10 5.4 0.0 2.8 3 0 0 3 3 3 0 Neurensin Profilin PF00235.14 CBZ29438.1 - 2.8e-38 130.7 0.1 3.4e-38 130.4 0.1 1.1 1 0 0 1 1 1 1 Profilin TauE PF01925.14 CBZ29440.1 - 1e-15 57.8 33.7 1.4e-13 50.8 0.3 3.0 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE DUF1903 PF08991.5 CBZ29441.1 - 0.00018 21.5 4.3 0.00018 21.5 3.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF1903) CHCH PF06747.8 CBZ29441.1 - 0.0045 16.8 12.2 0.091 12.7 1.7 2.5 2 0 0 2 2 2 2 CHCH domain CDI PF02234.14 CBZ29441.1 - 0.038 13.7 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Cmc1 PF08583.5 CBZ29441.1 - 0.064 13.0 12.6 0.33 10.7 0.2 2.8 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 CBZ29441.1 - 6.1 6.9 9.8 1.1 9.3 0.9 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 zf-C3HC4_3 PF13920.1 CBZ29442.1 - 2e-05 24.1 17.8 3.4e-05 23.4 12.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1691 PF07950.6 CBZ29442.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) DEAD PF00270.24 CBZ29443.1 - 1.5e-32 112.3 0.3 6.3e-32 110.3 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ29443.1 - 2.1e-25 88.4 0.2 7e-25 86.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ29443.1 - 5.2e-08 32.9 0.3 1.3e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CBZ29443.1 - 0.0046 15.7 0.0 0.012 14.4 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 CBZ29443.1 - 0.072 13.0 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 Helicase C-terminal domain Nucleoplasmin PF03066.10 CBZ29444.1 - 0.13 11.7 4.0 0.24 10.8 2.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 CBZ29444.1 - 0.22 11.2 3.4 0.45 10.3 2.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal Nop14 PF04147.7 CBZ29444.1 - 0.46 8.3 8.4 0.78 7.5 5.8 1.3 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.8 CBZ29444.1 - 1.9 8.0 16.4 0.13 11.8 7.6 1.8 2 0 0 2 2 2 0 YL1 nuclear protein PBP1_TM PF14812.1 CBZ29444.1 - 3.3 8.0 15.8 0.77 10.1 8.2 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PAT1 PF09770.4 CBZ29444.1 - 5.2 5.1 16.3 0.07 11.3 5.0 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Nucleo_P87 PF07267.6 CBZ29444.1 - 5.3 5.6 6.4 13 4.3 4.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 CBZ29444.1 - 7.1 4.5 7.3 11 3.8 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DnaJ PF00226.26 CBZ29445.1 - 2.3e-11 43.2 0.0 6.3e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.27 CBZ29447.1 - 1e-16 60.0 4.3 6.9e-05 22.5 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat MMS1_N PF10433.4 CBZ29447.1 - 0.047 11.8 0.0 0.09 10.9 0.0 1.5 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term AMMECR1 PF01871.12 CBZ29449.1 - 2.8e-47 160.0 0.0 3.4e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 DSPc PF00782.15 CBZ29450.1 - 8.9e-14 51.2 0.0 1.7e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ29450.1 - 2e-11 43.6 0.0 4.9e-11 42.4 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CBZ29450.1 - 4e-05 23.7 0.0 8.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 CBZ29450.1 - 4.4e-05 22.9 0.0 7.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 CBZ29450.1 - 0.0019 18.4 0.0 0.0043 17.3 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family AKAP7_NLS PF10469.4 CBZ29451.1 - 6.1e-43 146.9 0.0 7.5e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 CBZ29451.1 - 8.1e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily EF-hand_6 PF13405.1 CBZ29452.1 - 3.8e-11 41.9 0.9 0.00065 19.3 0.0 4.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.1 CBZ29452.1 - 1e-10 41.5 1.2 9.9e-06 25.6 0.3 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ29452.1 - 1.1e-09 36.8 1.7 0.00085 18.4 0.1 4.1 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 CBZ29452.1 - 1.1e-08 34.5 7.5 0.0041 16.6 0.4 4.9 2 1 3 5 5 5 3 EF-hand domain pair EFhand_Ca_insen PF08726.5 CBZ29452.1 - 7.1e-05 22.6 0.3 0.057 13.4 0.0 2.5 2 1 0 2 2 2 2 Ca2+ insensitive EF hand EF-hand_5 PF13202.1 CBZ29452.1 - 0.0012 18.0 1.6 0.62 9.5 0.0 3.4 3 0 0 3 3 3 2 EF hand DUF2465 PF10239.4 CBZ29452.1 - 0.044 12.9 0.1 0.061 12.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2465) Utp8 PF10395.4 CBZ29452.1 - 0.12 10.6 0.1 0.14 10.4 0.1 1.0 1 0 0 1 1 1 0 Utp8 family Kinesin PF00225.18 CBZ29454.1 - 3.4e-101 338.3 0.2 3.4e-101 338.3 0.2 2.9 2 0 0 2 2 2 1 Kinesin motor domain S4 PF01479.20 CBZ29455.1 - 0.00033 20.0 0.0 0.00061 19.1 0.0 1.5 1 0 0 1 1 1 1 S4 domain UQ_con PF00179.21 CBZ29456.1 - 1.1e-34 118.8 0.0 1.8e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mut7-C PF01927.11 CBZ29457.1 - 5.4e-48 162.7 0.4 8.6e-48 162.0 0.3 1.3 1 0 0 1 1 1 1 Mut7-C RNAse domain E6 PF00518.12 CBZ29457.1 - 0.092 13.0 1.5 0.35 11.2 1.1 2.0 1 1 1 2 2 2 0 Early Protein (E6) LSM PF01423.17 CBZ29458.1 - 1.3e-09 37.4 0.1 1.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain LRR_4 PF12799.2 CBZ29460.1 - 6.2e-15 54.4 1.4 3.1e-07 29.8 0.0 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ29460.1 - 7.5e-12 44.8 5.2 5.9e-08 32.3 1.1 4.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 CBZ29460.1 - 1.2e-05 24.8 0.5 0.72 10.1 0.1 4.2 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.28 CBZ29460.1 - 2.2e-05 23.8 6.9 1.8 8.8 0.0 6.1 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ29460.1 - 0.014 15.4 11.8 0.83 10.1 0.2 5.3 6 0 0 6 6 6 0 Leucine rich repeat RRM_6 PF14259.1 CBZ29462.1 - 1.4e-12 47.3 0.2 4.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ29462.1 - 3e-10 39.5 0.7 5.1e-05 22.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ29462.1 - 6.2e-08 32.3 0.4 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBZ29462.1 - 0.09 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 FAP PF07174.6 CBZ29462.1 - 5.7 6.1 18.2 8.1 5.6 12.6 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Cyclin_N PF00134.18 CBZ29463.1 - 1e-07 31.5 0.7 1.8e-07 30.7 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain RIC1 PF07064.8 CBZ29464.1 - 3.8e-66 223.1 0.0 6.1e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 RIC1 IKI3 PF04762.7 CBZ29464.1 - 0.017 12.9 0.0 0.55 7.9 0.0 2.7 3 0 0 3 3 3 0 IKI3 family DUF1561 PF07598.6 CBZ29464.1 - 0.11 10.4 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) Pkinase PF00069.20 CBZ29465.1 - 5e-50 170.0 0.0 8.2e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29465.1 - 4.8e-31 107.7 0.0 1.1e-30 106.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ29465.1 - 0.0003 20.6 0.0 0.00067 19.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBZ29465.1 - 0.063 12.1 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 CBZ29465.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 CBZ29468.1 - 7.3e-48 162.9 0.0 1.2e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29468.1 - 2.3e-35 121.9 0.0 4.2e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HAMP PF00672.20 CBZ29468.1 - 0.04 14.0 0.6 0.16 12.1 0.4 2.1 2 0 0 2 2 2 0 HAMP domain Filaggrin PF03516.8 CBZ29468.1 - 0.14 12.6 1.2 0.37 11.2 0.8 1.7 1 0 0 1 1 1 0 Filaggrin Cyclin PF08613.6 CBZ29469.1 - 3.3e-25 89.2 0.6 4.3e-25 88.8 0.4 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBZ29469.1 - 2e-10 40.3 0.5 2.5e-10 39.9 0.4 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain IFP_35_N PF07334.8 CBZ29470.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.7 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus RRM_5 PF13893.1 CBZ29471.1 - 1.6e-05 24.6 0.1 0.19 11.5 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ29471.1 - 0.0053 16.3 0.0 0.075 12.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 CBZ29471.1 - 4 5.5 36.0 5.7 5.0 24.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_5 PF13893.1 CBZ29472.1 - 2.6e-14 52.7 0.1 0.0088 15.8 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ29472.1 - 3e-14 52.7 0.1 0.0033 17.3 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ29472.1 - 2e-12 46.5 0.0 2.7e-05 23.7 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_2d PF01409.15 CBZ29474.1 - 3.9e-79 265.3 0.2 5.2e-79 264.9 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CBZ29474.1 - 2.9e-05 23.7 1.3 0.00011 21.8 0.8 2.2 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 CBZ29474.1 - 3.5e-05 22.7 2.7 4.5e-05 22.3 0.2 2.2 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) HTH_24 PF13412.1 CBZ29474.1 - 0.1 12.0 0.3 0.79 9.1 0.0 2.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding DUF465 PF04325.8 CBZ29474.1 - 0.67 9.7 2.7 0.63 9.7 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Ribosomal_L18ae PF01775.12 CBZ29475.1 - 6.5e-41 139.1 1.7 8.7e-41 138.7 1.2 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain CTP_transf_2 PF01467.21 CBZ29476.1 - 5.6e-31 107.7 0.1 6.7e-17 61.9 0.0 2.7 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 CBZ29476.1 - 0.00038 20.1 0.5 1.2 8.7 0.0 3.2 2 1 0 2 2 2 2 FAD synthetase AnfO_nitrog PF09582.5 CBZ29477.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Abhydrolase_6 PF12697.2 CBZ29478.1 - 3.6e-20 72.8 0.1 4.1e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ29478.1 - 2.7e-07 30.4 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ29478.1 - 0.00013 21.6 0.0 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CBZ29478.1 - 0.0004 20.0 0.1 0.0006 19.4 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.8 CBZ29478.1 - 0.0012 18.5 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Lipase_3 PF01764.20 CBZ29478.1 - 0.002 17.7 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.2 CBZ29478.1 - 0.0037 16.1 0.0 0.008 15.0 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 CBZ29478.1 - 0.016 14.4 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_9 PF10081.4 CBZ29478.1 - 0.022 13.4 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family PAF-AH_p_II PF03403.8 CBZ29478.1 - 0.059 11.6 0.0 0.13 10.5 0.0 1.5 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Cutinase PF01083.17 CBZ29478.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.8 CBZ29478.1 - 0.16 11.5 0.4 0.59 9.6 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold V_ATPase_I PF01496.14 CBZ29479.1 - 2.9e-194 647.1 1.3 3.5e-194 646.8 0.9 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GMC_oxred_N PF00732.14 CBZ29480.1 - 4e-07 29.4 0.0 0.00029 20.0 0.0 2.6 2 1 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 CBZ29480.1 - 5.6e-07 28.7 2.2 5.2e-06 25.6 1.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CBZ29480.1 - 6.9e-06 25.1 1.0 0.00087 18.2 0.2 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 CBZ29480.1 - 0.00051 20.0 0.2 0.0015 18.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CBZ29480.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBZ29480.1 - 0.0025 17.9 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CBZ29480.1 - 0.0025 16.7 0.1 0.0041 16.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 CBZ29480.1 - 0.0037 15.9 0.0 0.0061 15.2 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.9 CBZ29480.1 - 0.0069 14.9 0.2 0.0097 14.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 CBZ29480.1 - 0.015 15.0 0.1 0.03 14.0 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 CBZ29480.1 - 0.079 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A YajC PF02699.10 CBZ29480.1 - 0.19 11.4 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit CLASP_N PF12348.3 CBZ29481.1 - 5e-12 45.6 3.2 4.3e-10 39.3 1.7 2.6 2 0 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.2 CBZ29481.1 - 0.012 15.5 0.0 1.4 8.7 0.0 3.1 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Ipi1_N PF12333.3 CBZ29481.1 - 0.26 11.2 5.3 20 5.2 0.0 4.3 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 CBZ29481.1 - 0.26 11.4 25.9 6.1 7.2 0.0 8.3 9 0 0 9 9 9 0 HEAT repeat SNase PF00565.12 CBZ29482.1 - 3.5e-55 184.8 1.9 8.2e-16 58.2 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 CBZ29482.1 - 5.7e-17 61.6 0.0 1.3e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.7 CBZ29482.1 - 0.0059 16.7 0.0 0.028 14.5 0.0 2.2 1 0 0 1 1 1 1 Agenet domain DUF4537 PF15057.1 CBZ29482.1 - 0.073 12.8 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) SBBP PF06739.6 CBZ29482.1 - 0.42 10.4 3.5 0.52 10.1 0.5 2.3 2 0 0 2 2 2 0 Beta-propeller repeat UQ_con PF00179.21 CBZ29483.1 - 7.9e-41 138.7 0.0 1.1e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_C2 PF00648.16 CBZ29484.1 - 3.5e-05 22.9 0.0 8.1e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 Calpain family cysteine protease RRM_1 PF00076.17 CBZ29485.1 - 0.0063 16.1 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-B_box PF00643.19 CBZ29485.1 - 0.086 12.7 2.5 0.2 11.5 1.7 1.6 1 0 0 1 1 1 0 B-box zinc finger Vps23_core PF09454.5 CBZ29486.1 - 2.7e-19 68.5 0.1 8e-19 67.0 0.0 1.9 2 0 0 2 2 2 1 Vps23 core domain WD40 PF00400.27 CBZ29487.1 - 1.5e-11 43.7 4.0 2e-06 27.4 0.2 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 CBZ29488.1 - 6.4e-147 490.0 0.1 7.3e-147 489.8 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BESS PF02944.15 CBZ29488.1 - 0.055 13.0 0.1 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 BESS motif Y_phosphatase2 PF03162.8 CBZ29489.1 - 1.5e-22 79.6 0.0 1.5e-21 76.4 0.0 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Pkinase PF00069.20 CBZ29490.1 - 1.7e-30 106.0 0.1 1e-26 93.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29490.1 - 3.3e-16 59.1 0.1 7.3e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Maf PF02545.9 CBZ29491.1 - 3e-16 59.1 0.0 3.6e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein DUF3219 PF11514.3 CBZ29491.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) Lge1 PF11488.3 CBZ29492.1 - 0.047 13.8 0.2 0.047 13.8 0.1 3.6 4 1 0 4 4 4 0 Transcriptional regulatory protein LGE1 HR1 PF02185.11 CBZ29492.1 - 0.098 12.4 11.8 0.04 13.6 1.8 3.8 4 0 0 4 4 4 0 Hr1 repeat DUF445 PF04286.7 CBZ29492.1 - 0.44 10.0 15.0 0.023 14.2 1.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF445) MitMem_reg PF13012.1 CBZ29492.1 - 6.9 6.7 9.8 8.3 6.5 1.5 3.0 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Metallophos_2 PF12850.2 CBZ29493.1 - 6.5e-14 52.0 0.0 7.8e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.27 CBZ29494.1 - 1.5e-14 53.2 7.5 4.8e-05 23.0 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat LSM PF01423.17 CBZ29495.1 - 8.7e-14 50.8 0.1 1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain HECT PF00632.20 CBZ29497.1 - 1.6e-73 247.6 0.0 2.2e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.12 CBZ29497.1 - 0.00014 21.3 8.9 0.00042 19.7 6.1 1.8 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF2435 PF10363.4 CBZ29497.1 - 0.052 13.4 0.0 3.7 7.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) MUG2_C PF08593.5 CBZ29497.1 - 0.082 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Meiotically up-regulated glycoproteins C-terminal DUF3509 PF12021.3 CBZ29497.1 - 2.3 8.0 6.0 13 5.6 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3509) CRM1_C PF08767.6 CBZ29498.1 - 2.8e-60 203.8 0.7 2.8e-60 203.8 0.5 3.0 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 CBZ29498.1 - 1.4e-26 93.1 1.2 1.4e-26 93.1 0.8 3.6 5 1 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 CBZ29498.1 - 2.4e-08 33.7 0.0 2.4e-07 30.5 0.1 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain MHC_I_2 PF14586.1 CBZ29498.1 - 0.068 12.7 0.0 0.63 9.5 0.0 2.2 2 0 0 2 2 2 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 Mito_carr PF00153.22 CBZ29499.1 - 6.5e-48 160.4 0.8 2.1e-16 59.4 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF3815 PF12821.2 CBZ29499.1 - 0.015 15.2 2.6 0.017 15.0 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3815) Mito_carr PF00153.22 CBZ29500.1 - 5.6e-54 179.8 1.6 5e-19 67.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.1 CBZ29502.1 - 0.00086 19.2 0.1 9.5 6.2 0.0 3.9 4 1 0 4 4 4 2 PPR repeat family PPR_3 PF13812.1 CBZ29502.1 - 0.0046 17.1 12.0 0.1 12.9 0.0 6.0 7 0 0 7 7 7 1 Pentatricopeptide repeat domain ELO PF01151.13 CBZ29504.1 - 4.1e-52 176.9 18.5 5.4e-52 176.5 12.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Ank_2 PF12796.2 CBZ29506.1 - 4.9e-10 39.6 0.1 1.2e-09 38.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ29506.1 - 1.2e-08 34.3 3.0 0.00061 19.4 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CBZ29506.1 - 3.5e-08 33.7 0.4 1.4e-07 31.8 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ29506.1 - 1.2e-07 31.6 1.0 3.6e-07 30.1 0.7 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ29506.1 - 0.00025 21.0 0.6 0.057 13.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat PCI_Csn8 PF10075.4 CBZ29508.1 - 5e-26 91.1 0.0 6.9e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CBZ29508.1 - 1.4e-20 73.7 0.3 2e-20 73.2 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family HhH-GPD PF00730.20 CBZ29508.1 - 0.029 14.6 0.0 0.06 13.6 0.0 1.5 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein PD40 PF07676.7 CBZ29508.1 - 0.054 13.1 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat PPR_2 PF13041.1 CBZ29509.1 - 1.5e-39 133.7 19.8 1.7e-11 43.9 0.0 11.7 10 2 2 12 12 12 8 PPR repeat family PPR_3 PF13812.1 CBZ29509.1 - 8.4e-23 78.6 23.5 3.9e-05 23.5 0.0 13.4 16 0 0 16 16 16 5 Pentatricopeptide repeat domain PPR PF01535.15 CBZ29509.1 - 7.5e-14 50.6 13.1 8.2e-05 22.3 0.0 9.6 12 0 0 12 12 12 4 PPR repeat PPR_1 PF12854.2 CBZ29509.1 - 8.4e-09 34.7 19.3 3.7e-06 26.3 0.0 8.3 8 0 0 8 8 8 1 PPR repeat ECSIT PF06239.6 CBZ29509.1 - 0.0067 15.3 1.8 5.7 5.7 0.3 4.2 3 1 0 3 3 3 1 Evolutionarily conserved signalling intermediate in Toll pathway RPM2 PF08579.6 CBZ29509.1 - 0.013 15.6 3.6 5.4 7.1 0.8 4.8 3 1 1 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) COX5A PF02284.11 CBZ29509.1 - 0.044 13.7 0.0 3.6 7.5 0.0 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase subunit Va MNE1 PF13762.1 CBZ29509.1 - 0.13 12.2 3.1 25 4.9 0.0 4.3 3 1 0 4 4 4 0 Mitochondrial splicing apparatus component TSC22 PF01166.13 CBZ29510.1 - 8.8 6.3 10.7 0.14 12.1 0.2 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family ArfGap PF01412.13 CBZ29511.1 - 5.5e-28 97.0 0.0 1e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Apolipoprotein PF01442.13 CBZ29511.1 - 0.098 12.1 0.2 0.14 11.6 0.2 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TF_Zn_Ribbon PF08271.7 CBZ29511.1 - 0.15 11.4 2.7 0.26 10.6 1.9 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding PHTB1_N PF14727.1 CBZ29512.1 - 1.8e-92 310.5 0.0 3.5e-67 227.1 0.0 2.1 2 0 0 2 2 2 2 PTHB1 N-terminus PHTB1_C PF14728.1 CBZ29512.1 - 3.5e-48 164.2 0.0 5e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 PTHB1 C-terminus UCH PF00443.24 CBZ29513.1 - 1.5e-30 106.2 0.0 2.6e-30 105.4 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ29513.1 - 1.1e-18 67.7 0.0 5.9e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CRAL_TRIO PF00650.15 CBZ29514.1 - 4.5e-39 133.4 0.0 6.4e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.1 CBZ29514.1 - 0.00013 22.2 0.1 0.36 11.0 0.1 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.10 CBZ29514.1 - 0.021 14.9 0.0 0.052 13.6 0.0 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.15 CBZ29515.1 - 1.6e-30 105.6 0.0 3.5e-30 104.5 0.0 1.6 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CBZ29515.1 - 0.0023 17.8 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2066 PF09839.4 CBZ29515.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) SHS2_Rpb7-N PF03876.12 CBZ29516.1 - 1.8e-15 56.8 0.0 2.8e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase PF00069.20 CBZ29517.1 - 9.3e-10 38.0 0.0 2e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29517.1 - 5.8e-06 25.5 0.0 8.8e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ29517.1 - 9.7e-05 22.2 0.2 0.0003 20.6 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBZ29517.1 - 0.0029 17.2 0.0 0.0048 16.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pep_deformylase PF01327.16 CBZ29518.1 - 3e-26 91.7 0.0 3.9e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase DUF1158 PF06643.6 CBZ29518.1 - 0.15 12.3 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1158) WLM PF08325.5 CBZ29519.1 - 3.2e-32 111.9 0.0 7.4e-32 110.7 0.0 1.6 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 CBZ29519.1 - 0.0078 16.0 2.0 0.015 15.1 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-ribbon_3 PF13248.1 CBZ29519.1 - 1.6 8.0 7.0 4 6.7 4.8 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Peptidase_C97 PF05903.9 CBZ29521.1 - 2.4e-14 53.3 0.1 4.4e-14 52.5 0.1 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain CPSF_A PF03178.10 CBZ29522.1 - 9.2e-60 202.3 0.0 1.5e-59 201.7 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 CBZ29522.1 - 8.7e-10 37.3 0.0 5.9e-07 27.9 0.0 2.7 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term LicD PF04991.8 CBZ29523.1 - 2.3e-09 37.6 0.0 4.1e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 LicD family AAA_17 PF13207.1 CBZ29524.1 - 4.2e-08 34.0 0.0 1e-07 32.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain mRNA_cap_enzyme PF01331.14 CBZ29524.1 - 1.3e-07 31.5 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain ADK PF00406.17 CBZ29524.1 - 5.6e-07 29.5 0.0 1.3e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.1 CBZ29524.1 - 0.00041 20.2 0.0 0.00077 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ29524.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain mRNA_cap_C PF03919.10 CBZ29524.1 - 0.0014 18.9 0.0 0.0045 17.2 0.0 2.0 2 0 0 2 2 1 1 mRNA capping enzyme, C-terminal domain Thymidylate_kin PF02223.12 CBZ29524.1 - 0.0027 17.1 0.0 0.82 9.0 0.0 2.4 1 1 1 2 2 2 2 Thymidylate kinase DNA_ligase_A_M PF01068.16 CBZ29524.1 - 0.013 14.8 0.0 2.8 7.2 0.0 2.3 2 0 0 2 2 2 0 ATP dependent DNA ligase domain AAA_22 PF13401.1 CBZ29524.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CBZ29524.1 - 0.038 13.7 0.1 0.64 9.7 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CBZ29524.1 - 0.043 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CBZ29524.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBZ29524.1 - 0.075 12.1 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SRP54 PF00448.17 CBZ29524.1 - 0.077 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 CBZ29524.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CBZ29524.1 - 0.21 11.7 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ29525.1 - 2e-06 28.5 0.0 6.2e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 CBZ29525.1 - 0.0027 17.3 0.0 0.0054 16.4 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CBZ29525.1 - 0.031 14.1 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBZ29525.1 - 0.039 13.9 0.3 0.1 12.6 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 CBZ29525.1 - 0.053 13.7 0.1 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CBZ29525.1 - 0.12 11.3 0.2 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CBZ29525.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sec63 PF02889.11 CBZ29528.1 - 1.8e-39 135.7 0.0 1.8e-36 125.9 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CBZ29528.1 - 2.2e-22 79.3 0.7 1.8e-21 76.4 0.5 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ29528.1 - 7.3e-08 32.1 0.0 1.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ29528.1 - 6e-06 26.2 0.0 3.7e-05 23.6 0.0 2.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit T2SE PF00437.15 CBZ29528.1 - 0.013 14.4 0.0 0.038 12.8 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD-helicase PF00580.16 CBZ29528.1 - 0.14 11.4 0.0 0.33 10.2 0.0 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 CBZ29528.1 - 0.19 11.8 0.1 8.2 6.5 0.1 2.7 1 1 0 1 1 1 0 AAA domain Cyclase PF04199.8 CBZ29529.1 - 1.3e-29 103.0 0.0 2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Chloroa_b-bind PF00504.16 CBZ29532.1 - 0.031 14.5 0.7 0.031 14.5 0.5 1.4 1 1 0 1 1 1 0 Chlorophyll A-B binding protein Gemini_AL2 PF01440.11 CBZ29532.1 - 0.12 12.4 0.1 0.17 11.9 0.1 1.2 1 0 0 1 1 1 0 Geminivirus AL2 protein PI3_PI4_kinase PF00454.22 CBZ29534.1 - 4.5e-38 131.0 0.3 1e-37 129.9 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CBZ29534.1 - 1.8e-12 46.9 0.3 7.6e-12 44.8 0.2 2.1 1 1 0 1 1 1 1 FAT domain FATC PF02260.15 CBZ29534.1 - 3.4e-12 45.5 4.0 4.8e-12 45.0 1.0 2.7 2 0 0 2 2 2 1 FATC domain MIP-T3 PF10243.4 CBZ29535.1 - 3.9e-15 55.3 2.6 3.9e-15 55.3 1.8 1.6 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 rRNA_processing PF08524.6 CBZ29537.1 - 4.5e-09 36.2 15.5 4.5e-09 36.2 10.7 2.2 1 1 1 2 2 2 1 rRNA processing DUF918 PF06033.6 CBZ29537.1 - 0.29 10.6 4.9 0.49 9.9 3.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) VGLL4 PF15245.1 CBZ29537.1 - 0.62 9.8 14.1 1.3 8.8 9.7 1.6 1 1 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Peptidase_M41 PF01434.13 CBZ29539.1 - 4.9e-50 169.9 0.4 7.7e-50 169.3 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBZ29539.1 - 4.8e-41 140.0 0.0 9.5e-41 139.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ29539.1 - 0.0003 20.8 0.2 0.0025 17.8 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CBZ29539.1 - 0.0013 18.3 0.4 0.0047 16.6 0.3 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CBZ29539.1 - 0.002 18.2 0.1 0.014 15.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBZ29539.1 - 0.0029 17.0 0.8 0.021 14.2 0.2 2.2 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CBZ29539.1 - 0.0061 15.6 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 CBZ29539.1 - 0.0073 15.0 0.1 0.015 14.0 0.0 1.5 1 1 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 CBZ29539.1 - 0.013 15.2 0.1 0.08 12.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CBZ29539.1 - 0.015 14.3 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 CBZ29539.1 - 0.015 16.0 0.0 0.038 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 CBZ29539.1 - 0.023 14.0 0.1 0.05 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 CBZ29539.1 - 0.031 13.7 0.0 0.16 11.4 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 CBZ29539.1 - 0.034 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CBZ29539.1 - 0.055 12.4 0.1 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 CBZ29539.1 - 0.1 12.2 0.0 0.82 9.3 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 CBZ29539.1 - 0.14 12.4 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 CBZ29539.1 - 0.19 11.5 0.7 2.1 8.2 0.4 2.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) YqaJ PF09588.5 CBZ29541.1 - 1.9e-56 190.2 0.0 4.7e-56 188.9 0.0 1.7 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain NUDIX PF00293.23 CBZ29544.1 - 8.8e-07 28.6 0.0 1.4e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain PSP1 PF04468.7 CBZ29545.1 - 7.3e-25 86.7 1.3 1.1e-24 86.2 0.9 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region eIF3_p135 PF12807.2 CBZ29546.1 - 3.4e-12 46.6 0.0 5.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 ArfGap PF01412.13 CBZ29547.1 - 1.8e-41 140.5 0.2 3e-41 139.8 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PMI_typeI PF01238.16 CBZ29548.1 - 1.1e-88 297.7 0.0 1.3e-88 297.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I LcrG PF07216.7 CBZ29548.1 - 0.028 14.4 0.0 0.099 12.6 0.0 1.8 2 0 0 2 2 2 0 LcrG protein PIF1 PF05970.9 CBZ29549.1 - 8.8e-36 123.5 0.1 2.4e-15 56.3 0.0 4.2 4 0 0 4 4 4 4 PIF1-like helicase AAA_30 PF13604.1 CBZ29549.1 - 2.3e-11 43.6 0.2 5.6e-08 32.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 CBZ29549.1 - 5.7e-06 25.9 0.6 1.8e-05 24.4 0.4 1.8 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CBZ29549.1 - 0.00017 21.1 0.2 4.7 6.6 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 CBZ29549.1 - 0.00034 18.5 3.6 0.14 9.8 0.3 2.4 3 0 0 3 3 3 2 Helicase IstB_IS21 PF01695.12 CBZ29549.1 - 0.00092 18.6 0.2 0.0039 16.6 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 CBZ29549.1 - 0.0013 18.8 0.0 0.076 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ29549.1 - 0.0014 18.6 0.1 0.0045 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 CBZ29549.1 - 0.0024 18.0 0.0 0.0079 16.3 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 CBZ29549.1 - 0.0035 17.0 0.1 0.16 11.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 CBZ29549.1 - 0.011 15.4 0.0 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein Helicase_RecD PF05127.9 CBZ29549.1 - 0.012 15.2 0.4 1 8.9 0.2 2.4 2 0 0 2 2 2 0 Helicase MobB PF03205.9 CBZ29549.1 - 0.012 15.3 0.1 0.043 13.5 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 CBZ29549.1 - 0.024 13.8 0.1 0.048 12.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ArgK PF03308.11 CBZ29549.1 - 0.025 13.3 0.2 0.055 12.2 0.1 1.5 1 0 0 1 1 1 0 ArgK protein NACHT PF05729.7 CBZ29549.1 - 0.033 13.8 0.1 0.065 12.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 CBZ29549.1 - 0.044 14.0 1.4 0.074 13.3 0.4 1.7 2 0 0 2 2 1 0 ABC transporter AAA_25 PF13481.1 CBZ29549.1 - 0.046 13.1 0.2 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CBZ29549.1 - 0.079 12.3 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 CBZ29549.1 - 0.08 12.0 0.2 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 CBZ29549.1 - 0.1 12.3 0.1 0.6 9.8 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.1 CBZ29549.1 - 0.11 12.0 0.1 19 4.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CBZ29549.1 - 0.11 11.0 0.1 0.18 10.4 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.1 CBZ29549.1 - 0.12 11.8 0.1 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3670 PF12419.3 CBZ29553.1 - 0.087 12.2 0.1 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 SNF2 Helicase protein NAD_synthase PF02540.12 CBZ29557.1 - 2.1e-33 115.2 0.0 2.7e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 CBZ29557.1 - 0.039 13.4 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.14 CBZ29557.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family PP2C PF00481.16 CBZ29559.1 - 8.6e-68 228.4 0.0 1.3e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoU_methylase PF00588.14 CBZ29561.1 - 3.6e-09 36.6 0.2 0.011 15.5 0.0 4.1 4 0 0 4 4 4 3 SpoU rRNA Methylase family DNA_pol_E_B PF04042.11 CBZ29562.1 - 2e-12 46.8 0.1 1.3e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Coatomer_E PF04733.9 CBZ29563.1 - 2.8e-30 105.5 5.8 1.2e-29 103.4 4.0 1.8 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 CBZ29563.1 - 4e-07 30.2 3.9 0.0065 16.7 0.5 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ29563.1 - 3.4e-06 26.6 0.6 3.4e-06 26.6 0.4 3.4 4 1 0 4 4 4 1 TPR repeat TPR_16 PF13432.1 CBZ29563.1 - 4e-06 27.3 14.1 0.0005 20.6 1.5 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ29563.1 - 2.3e-05 24.6 9.5 0.18 12.5 0.9 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ29563.1 - 2.8e-05 23.7 5.8 0.31 11.0 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ29563.1 - 0.00031 20.6 2.5 0.00031 20.6 1.7 3.7 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ29563.1 - 0.00082 18.8 2.9 0.48 10.1 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ29563.1 - 0.0018 18.1 1.7 0.78 9.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ29563.1 - 0.0078 16.3 2.9 0.52 10.4 0.7 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Dispanin PF04505.7 CBZ29563.1 - 0.093 12.2 0.8 1.8 8.1 0.0 2.7 2 0 0 2 2 2 0 Interferon-induced transmembrane protein TPR_7 PF13176.1 CBZ29563.1 - 0.15 11.9 3.0 9.6 6.2 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ29563.1 - 0.2 11.5 5.8 4.5 7.2 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat WW PF00397.21 CBZ29564.1 - 7e-12 44.9 1.2 1.1e-11 44.3 0.8 1.4 1 0 0 1 1 1 1 WW domain zf-CCCH PF00642.19 CBZ29564.1 - 3e-06 26.7 0.6 3e-06 26.7 0.4 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CBZ29564.1 - 0.034 14.1 0.2 0.076 13.0 0.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type CBM_2 PF00553.14 CBZ29564.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Cellulose binding domain PUF PF00806.14 CBZ29565.1 - 1.8e-23 80.6 0.0 0.0095 15.3 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat PBP PF01161.15 CBZ29567.1 - 1.4e-06 28.1 0.4 3e-06 27.1 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein DUF4407 PF14362.1 CBZ29570.1 - 0.68 8.8 6.7 0.89 8.4 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop14 PF04147.7 CBZ29570.1 - 0.77 7.6 9.6 0.94 7.3 6.6 1.0 1 0 0 1 1 1 0 Nop14-like family Golgin_A5 PF09787.4 CBZ29571.1 - 0.0033 16.0 0.4 0.0037 15.8 0.2 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 5 PmbA_TldD PF01523.11 CBZ29571.1 - 0.0087 15.3 0.5 0.0097 15.2 0.4 1.1 1 0 0 1 1 1 1 Putative modulator of DNA gyrase Herpes_capsid PF06112.6 CBZ29571.1 - 0.78 9.7 5.6 1.2 9.1 3.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pkinase PF00069.20 CBZ29572.1 - 1.2e-43 149.1 0.0 3.4e-43 147.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29572.1 - 7.5e-30 103.8 0.0 3.1e-29 101.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 CBZ29572.1 - 7.6e-07 29.2 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CBZ29572.1 - 0.0001 21.3 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.1 CBZ29572.1 - 0.0027 17.8 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 CBZ29572.1 - 0.078 12.6 0.3 0.26 10.9 0.2 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sod_Fe_C PF02777.13 CBZ29573.1 - 1.3e-42 143.9 0.1 2.2e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBZ29573.1 - 2e-18 66.4 0.2 2e-18 66.4 0.2 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 CBZ29574.1 - 4.3e-42 142.2 0.2 7.3e-42 141.5 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBZ29574.1 - 3.9e-18 65.4 0.1 3.9e-18 65.4 0.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ras PF00071.17 CBZ29575.1 - 4e-36 123.8 0.0 4.9e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ29575.1 - 1.7e-16 60.8 0.0 2.4e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ29575.1 - 2.6e-10 39.8 0.0 3.3e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ29575.1 - 4.2e-07 29.3 0.0 4.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CBZ29575.1 - 6.6e-07 28.7 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CBZ29575.1 - 2.9e-06 26.8 0.0 0.00018 21.0 0.0 2.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ29575.1 - 1.9e-05 24.5 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CBZ29575.1 - 0.0016 18.0 0.1 0.0026 17.3 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 CBZ29575.1 - 0.15 12.1 0.0 1 9.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain Cpn60_TCP1 PF00118.19 CBZ29576.1 - 2.1e-119 399.2 3.5 2.6e-119 399.0 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AKAP95 PF04988.7 CBZ29576.1 - 0.062 13.0 0.0 15 5.2 0.0 3.1 3 0 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Cation_efflux PF01545.16 CBZ29578.1 - 3.3e-62 210.1 1.4 4.5e-62 209.6 0.9 1.1 1 0 0 1 1 1 1 Cation efflux family CBFD_NFYB_HMF PF00808.18 CBZ29579.1 - 0.00063 19.7 0.0 0.00091 19.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DNA_pol_A_exo1 PF01612.15 CBZ29580.1 - 6.5e-09 35.5 0.0 3.7e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease DUF647 PF04884.9 CBZ29584.1 - 5.9e-21 74.7 7.1 8.8e-21 74.2 5.0 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis GVQW PF13900.1 CBZ29584.1 - 0.013 15.4 0.2 0.3 11.1 0.1 2.6 2 0 0 2 2 2 0 Putative binding domain CTDII PF01556.13 CBZ29586.1 - 7.9e-26 89.7 0.0 2e-20 72.4 0.0 2.5 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 CBZ29586.1 - 7.5e-16 57.6 1.0 1.5e-15 56.6 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain Acyltransferase PF01553.16 CBZ29588.1 - 5.6e-16 58.1 0.0 1.6e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase DUF367 PF04034.8 CBZ29590.1 - 1e-47 160.9 0.0 1.4e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CBZ29590.1 - 2.2e-10 39.9 0.0 4.6e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF4200 PF13863.1 CBZ29592.1 - 9.8e-25 86.9 13.8 9.8e-25 86.9 9.6 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4200) DUF1664 PF07889.7 CBZ29592.1 - 0.43 10.3 4.2 4.7 7.0 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Endosulfine PF04667.12 CBZ29593.1 - 1e-07 31.8 0.6 1.6e-07 31.1 0.4 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF3456 PF11938.3 CBZ29594.1 - 4.1e-10 39.8 4.8 1.4e-09 38.0 1.2 2.7 2 1 0 2 2 2 1 TLR4 regulator and MIR-interacting MSAP MIR PF02815.14 CBZ29595.1 - 0.0089 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 MIR domain EMP24_GP25L PF01105.19 CBZ29596.1 - 6e-31 107.5 0.0 6.6e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ras PF00071.17 CBZ29597.1 - 1.9e-60 202.9 0.0 2.2e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ29597.1 - 9.7e-19 68.0 0.0 1.5e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ29597.1 - 1.8e-12 46.8 0.0 2.1e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ29597.1 - 0.0001 21.5 0.0 0.00015 20.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CBZ29597.1 - 0.00029 20.3 0.0 0.0011 18.3 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ29597.1 - 0.00059 19.7 0.0 0.00085 19.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 CBZ29597.1 - 0.014 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain FA_synthesis PF02504.10 CBZ29597.1 - 0.02 13.7 0.1 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 Fatty acid synthesis protein AAA_22 PF13401.1 CBZ29597.1 - 0.024 14.7 0.1 0.055 13.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CBZ29597.1 - 0.029 13.5 0.0 0.081 12.1 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF258 DUF3234 PF11572.3 CBZ29597.1 - 0.042 13.9 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3234) AAA_16 PF13191.1 CBZ29597.1 - 0.067 13.1 0.2 0.13 12.2 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CBZ29597.1 - 0.13 11.8 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CBZ29600.1 - 9.2e-18 64.8 0.0 1.7e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ29600.1 - 9.7e-13 48.7 0.1 1.4e-07 31.7 0.1 2.2 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 CBZ29600.1 - 7.7e-07 28.5 0.0 3.8e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CBZ29600.1 - 0.00043 19.4 0.0 0.0028 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CBZ29600.1 - 0.00049 19.3 0.0 0.00098 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_membrane PF00664.18 CBZ29600.1 - 0.00055 19.4 4.3 0.0012 18.3 3.0 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.1 CBZ29600.1 - 0.001 19.0 0.3 0.0039 17.1 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBZ29600.1 - 0.002 18.2 1.2 0.023 14.8 0.8 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CBZ29600.1 - 0.0028 17.8 0.2 0.18 12.0 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 CBZ29600.1 - 0.0064 16.8 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBZ29600.1 - 0.011 15.1 0.3 0.056 12.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CBZ29600.1 - 0.015 15.2 0.0 0.091 12.6 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 CBZ29600.1 - 0.022 13.2 0.1 3.6 5.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 CBZ29600.1 - 0.041 12.5 0.0 0.066 11.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_29 PF13555.1 CBZ29600.1 - 0.052 13.0 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 CBZ29600.1 - 0.056 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 CBZ29600.1 - 0.11 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Rad17 PF03215.10 CBZ29600.1 - 0.15 10.7 0.3 0.23 10.1 0.2 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CBZ29600.1 - 0.33 11.7 0.8 0.65 10.8 0.1 1.8 2 0 0 2 2 1 0 AAA domain CTP_transf_2 PF01467.21 CBZ29601.1 - 9e-08 32.3 0.0 1.6e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 CBZ29601.1 - 0.061 12.9 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase dCMP_cyt_deam_1 PF00383.17 CBZ29602.1 - 3.4e-07 29.8 0.0 1e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CBZ29602.1 - 0.0016 18.3 0.1 0.0059 16.4 0.0 2.0 2 0 0 2 2 2 1 Bd3614-like deaminase Methyltransf_26 PF13659.1 CBZ29603.1 - 3.7e-15 55.9 0.2 7.7e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ29603.1 - 0.05 13.9 0.1 0.58 10.5 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 CBZ29603.1 - 0.11 11.8 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 TMPIT PF07851.8 CBZ29604.1 - 0.15 11.1 2.5 0.3 10.1 1.7 1.4 1 0 0 1 1 1 0 TMPIT-like protein Tropomyosin_1 PF12718.2 CBZ29604.1 - 0.41 10.4 28.3 0.65 9.8 0.2 3.7 4 0 0 4 4 4 0 Tropomyosin like DUF677 PF05055.7 CBZ29604.1 - 8.9 4.8 13.2 0.056 12.1 2.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF677) RRM_1 PF00076.17 CBZ29607.1 - 3.1e-09 36.3 0.0 5.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ29607.1 - 1.3e-05 25.0 0.1 2.8e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 CBZ29607.1 - 0.00014 21.9 0.1 0.00048 20.1 0.0 1.9 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 CBZ29607.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ29607.1 - 0.075 12.8 0.1 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Menin PF05053.8 CBZ29607.1 - 0.47 8.5 5.2 0.62 8.1 3.6 1.1 1 0 0 1 1 1 0 Menin HEAT PF02985.17 CBZ29609.1 - 3.3e-09 36.0 8.4 0.052 13.6 0.3 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 CBZ29609.1 - 4.4e-09 36.5 4.5 0.51 10.9 0.0 7.0 7 0 0 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.1 CBZ29609.1 - 2.3e-07 31.0 0.5 0.00043 20.5 0.0 4.7 4 1 1 5 5 5 2 HEAT repeats Cnd1 PF12717.2 CBZ29609.1 - 8.8e-05 22.4 0.1 0.00097 19.0 0.0 2.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.7 CBZ29609.1 - 0.013 15.4 0.2 7.6 6.4 0.0 4.3 4 1 1 5 5 5 0 Exportin 1-like protein Utp12 PF04003.7 CBZ29609.1 - 0.025 14.4 0.1 0.51 10.2 0.0 3.1 4 0 0 4 4 4 0 Dip2/Utp12 Family Synaptobrevin PF00957.16 CBZ29611.1 - 4.5e-09 35.7 4.3 9.5e-09 34.7 3.0 1.4 1 0 0 1 1 1 1 Synaptobrevin EcoR124_C PF12008.3 CBZ29611.1 - 0.29 10.2 0.9 0.44 9.6 0.6 1.2 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal PCI_Csn8 PF10075.4 CBZ29613.1 - 5.2e-14 52.2 0.0 9.2e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CBZ29613.1 - 2.2e-11 43.7 0.0 2.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 CBZ29613.1 - 0.0011 19.2 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 PCI domain GTP_EFTU PF00009.22 CBZ29615.1 - 3e-24 85.4 0.0 4.7e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CBZ29615.1 - 3.6e-15 55.5 0.0 8.1e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CBZ29615.1 - 3.9e-08 33.0 0.0 7.8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CBZ29615.1 - 1.2e-07 31.2 0.0 2.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV Miro PF08477.8 CBZ29615.1 - 4.9e-07 30.2 0.0 8.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBZ29615.1 - 4.3e-06 26.6 0.0 7.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CBZ29615.1 - 1.2e-05 25.1 0.1 0.0061 16.3 0.0 2.3 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.5 CBZ29615.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Septin PF00735.13 CBZ29615.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Septin Complex1_LYR PF05347.10 CBZ29616.1 - 5.5e-12 45.2 1.0 1.2e-11 44.1 0.7 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBZ29616.1 - 1.1e-09 38.3 0.7 1.1e-09 38.3 0.5 1.9 2 0 0 2 2 2 1 Complex1_LYR-like Mg-por_mtran_C PF07109.6 CBZ29616.1 - 0.15 12.1 0.3 2.1 8.4 0.1 2.3 2 1 0 2 2 2 0 Magnesium-protoporphyrin IX methyltransferase C-terminus DnaB_bind PF10410.4 CBZ29616.1 - 5.1 7.1 5.8 21 5.2 0.1 3.1 3 1 1 4 4 4 0 DnaB-helicase binding domain of primase Spc7 PF08317.6 CBZ29617.1 - 1.9e-06 26.7 12.6 1.9e-06 26.7 8.8 9.0 2 1 7 10 10 10 2 Spc7 kinetochore protein Fib_alpha PF08702.5 CBZ29617.1 - 0.0026 17.8 4.8 0.0026 17.8 3.3 10.0 2 1 12 14 14 14 1 Fibrinogen alpha/beta chain family DUF3135 PF11333.3 CBZ29617.1 - 0.032 14.3 99.0 1.1 9.4 2.3 12.1 5 1 6 11 11 11 0 Protein of unknown function (DUF3135) BBP1_C PF15272.1 CBZ29617.1 - 3.1 7.2 153.1 0.025 14.1 10.7 10.1 2 2 8 10 10 10 0 Spindle pole body component BBP1, C-terminal DEAD PF00270.24 CBZ29618.1 - 5.9e-40 136.5 0.0 1.2e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ29618.1 - 4.3e-21 74.5 0.0 1.1e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBZ29618.1 - 1.3e-13 50.2 0.1 3.9e-13 48.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBZ29618.1 - 0.0081 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Formyl_trans_N PF00551.14 CBZ29619.1 - 6e-16 58.5 0.0 1.2e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase CS PF04969.11 CBZ29621.1 - 0.00011 22.6 0.0 0.00011 22.6 0.0 1.7 2 0 0 2 2 2 1 CS domain ERG4_ERG24 PF01222.12 CBZ29627.1 - 1.5e-125 419.1 1.9 1.7e-125 418.9 1.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CBZ29627.1 - 6.9e-08 32.0 0.2 2e-07 30.5 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 CBZ29627.1 - 4.3e-06 26.7 0.0 2.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 CBZ29627.1 - 0.0043 17.2 0.0 0.0043 17.2 0.0 3.2 4 0 0 4 4 4 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NAD_binding_1 PF00175.16 CBZ29629.1 - 1e-16 61.4 0.0 3.6e-14 53.2 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CBZ29629.1 - 9.6e-12 44.8 0.0 1.6e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CBZ29629.1 - 0.0002 21.2 0.0 0.0011 18.8 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Nsp1_C PF05064.8 CBZ29630.1 - 2.5e-10 40.0 1.1 4.2e-10 39.2 0.8 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Myosin_tail_1 PF01576.14 CBZ29630.1 - 0.018 12.8 5.2 0.025 12.3 3.6 1.2 1 0 0 1 1 1 0 Myosin tail Cluap1 PF10234.4 CBZ29630.1 - 0.068 12.3 1.1 0.1 11.7 0.8 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Golgin_A5 PF09787.4 CBZ29630.1 - 0.88 8.0 8.4 0.15 10.5 3.2 1.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 IncA PF04156.9 CBZ29630.1 - 1.5 8.3 7.1 6.8 6.2 5.0 2.2 1 1 0 1 1 1 0 IncA protein PPR_3 PF13812.1 CBZ29631.1 - 0.00065 19.7 0.2 7.4 7.1 0.0 5.3 5 0 0 5 5 5 1 Pentatricopeptide repeat domain MIP PF00230.15 CBZ29632.1 - 5.6e-35 120.8 16.4 6.9e-35 120.5 11.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein FA_desaturase PF00487.19 CBZ29632.1 - 3 7.2 8.5 2.6e+02 0.8 5.9 2.6 1 1 0 1 1 1 0 Fatty acid desaturase MIP PF00230.15 CBZ29633.1 - 2.9e-30 105.4 14.6 4.2e-30 104.9 10.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein DNA_pol_lambd_f PF10391.4 CBZ29635.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Kelch_4 PF13418.1 CBZ29636.1 - 1.7e-08 34.1 0.1 0.0077 15.9 0.0 4.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CBZ29636.1 - 1.6e-06 28.0 0.2 0.016 15.3 0.1 3.8 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 CBZ29636.1 - 8.6e-06 25.5 2.7 0.036 14.0 0.2 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.20 CBZ29636.1 - 7.2e-05 22.2 0.3 0.0011 18.5 0.1 3.0 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 CBZ29636.1 - 0.00031 20.8 4.1 0.005 16.9 0.0 4.1 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 CBZ29636.1 - 0.012 15.3 2.5 0.21 11.4 0.4 3.1 3 0 0 3 3 3 0 Kelch motif TPR_12 PF13424.1 CBZ29637.1 - 1.4e-08 34.5 11.8 1.3e-07 31.4 2.7 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ29637.1 - 3.5e-08 32.9 8.1 1.9e-06 27.4 2.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 CBZ29637.1 - 0.0013 18.2 9.9 2.7 7.7 0.2 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ29637.1 - 0.002 17.9 13.2 0.24 11.4 0.7 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ29637.1 - 0.009 15.9 0.1 0.009 15.9 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 CBZ29637.1 - 0.059 13.2 7.6 0.056 13.3 1.0 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 CBZ29637.1 - 1.1 9.2 7.5 1.3 9.0 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Nol1_Nop2_Fmu PF01189.12 CBZ29639.1 - 7.9e-24 84.5 0.0 1.2e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CBZ29639.1 - 7.5e-05 22.7 0.1 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ29639.1 - 0.0023 18.4 0.0 0.0054 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NUDIX PF00293.23 CBZ29640.1 - 1.9e-06 27.5 0.0 5e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain PAP_assoc PF03828.14 CBZ29641.1 - 5.9e-08 32.5 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 CBZ29641.1 - 0.0011 19.3 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Glyoxalase PF00903.20 CBZ29642.1 - 0.17 11.8 0.1 0.42 10.5 0.1 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TPR_14 PF13428.1 CBZ29644.1 - 0.00017 21.9 50.7 0.18 12.5 0.8 12.0 12 1 1 13 13 13 3 Tetratricopeptide repeat PRP1_N PF06424.7 CBZ29644.1 - 0.00067 19.9 0.7 0.0015 18.8 0.5 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_2 PF07719.12 CBZ29644.1 - 0.0029 17.4 1.7 0.0029 17.4 1.2 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ29644.1 - 0.0043 17.1 1.2 6.9 7.1 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ29644.1 - 0.016 14.7 1.2 0.25 11.0 1.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ29644.1 - 0.021 14.9 0.9 0.63 10.2 0.1 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 CBZ29644.1 - 0.024 14.3 14.1 0.092 12.4 0.6 5.1 7 1 2 9 9 9 0 TPR repeat TPR_8 PF13181.1 CBZ29644.1 - 0.28 11.0 2.6 2.5 8.0 0.3 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat cNMP_binding PF00027.24 CBZ29648.1 - 7.2e-13 48.1 0.0 3e-05 23.7 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain HD PF01966.17 CBZ29649.1 - 2.2e-07 30.9 0.1 7.7e-07 29.1 0.0 2.1 1 0 0 1 1 1 1 HD domain A_deaminase PF00962.17 CBZ29650.1 - 3e-80 269.6 0.2 6.2e-61 206.1 0.0 2.3 2 0 0 2 2 2 2 Adenosine/AMP deaminase DUF1192 PF06698.6 CBZ29650.1 - 0.037 13.8 0.1 0.15 11.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4530 PF15039.1 CBZ29650.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) DUF972 PF06156.8 CBZ29650.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4603 PF15376.1 CBZ29650.1 - 0.99 6.5 0.0 1.5 5.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Ctr PF04145.10 CBZ29651.1 - 0.0029 17.6 0.4 0.56 10.2 0.0 2.6 2 0 0 2 2 2 2 Ctr copper transporter family WD40 PF00400.27 CBZ29653.1 - 2.8e-05 23.8 0.5 6.3 6.8 0.0 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat CHCH PF06747.8 CBZ29654.1 - 0.0022 17.8 2.9 0.0034 17.2 2.0 1.3 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 CBZ29654.1 - 0.058 13.5 1.0 0.11 12.6 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) DUF1661 PF07877.6 CBZ29654.1 - 3.4 7.2 4.8 0.54 9.7 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1661) DUF1908 PF08926.6 CBZ29655.1 - 0.0034 16.2 0.2 0.0034 16.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1908) Complex1_LYR_2 PF13233.1 CBZ29657.1 - 4.9e-11 43.0 0.1 8.2e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CBZ29657.1 - 0.0062 16.3 0.6 0.021 14.6 0.4 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBZ29657.1 - 0.021 15.0 0.4 0.055 13.6 0.3 1.7 1 1 0 1 1 1 0 Complex1_LYR-like DUF2456 PF10445.4 CBZ29657.1 - 0.054 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) ArsA_ATPase PF02374.10 CBZ29657.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase Sod_Fe_C PF02777.13 CBZ29658.1 - 3.1e-32 110.5 1.0 7.2e-32 109.3 0.7 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CBZ29658.1 - 8.7e-19 67.5 0.1 2e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cys_Met_Meta_PP PF01053.15 CBZ29659.1 - 7.1e-91 304.3 0.0 8.3e-91 304.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CBZ29659.1 - 2.8e-07 29.8 0.0 4.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBZ29659.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CBZ29659.1 - 0.0018 17.3 0.0 0.0074 15.3 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CBZ29659.1 - 0.0022 16.8 0.0 0.0034 16.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V HyaE PF07449.6 CBZ29659.1 - 0.086 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE SpoU_methylase PF00588.14 CBZ29660.1 - 4e-24 85.1 0.0 4.1e-23 81.8 0.0 2.8 4 0 0 4 4 4 1 SpoU rRNA Methylase family Aa_trans PF01490.13 CBZ29661.1 - 4.4e-52 176.9 29.2 5.4e-52 176.6 20.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ29661.1 - 3.7e-10 39.1 8.1 3.7e-10 39.1 5.6 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family DUF1539 PF07560.6 CBZ29662.1 - 0.18 11.6 0.6 0.93 9.3 0.2 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) NADH-u_ox-rdase PF10785.4 CBZ29663.1 - 1.9 8.7 5.1 35 4.7 0.0 3.8 4 1 0 4 4 4 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Ribosomal_L27e PF01777.13 CBZ29664.1 - 1.4e-26 92.4 1.8 1.8e-26 92.0 1.2 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CBZ29664.1 - 6.2e-06 25.7 0.6 1.6e-05 24.3 0.4 1.7 1 0 0 1 1 1 1 KOW motif Ribonuclease_P PF00825.13 CBZ29664.1 - 0.073 12.9 2.5 0.1 12.4 1.7 1.7 1 1 0 1 1 1 0 Ribonuclease P Ribosomal_L27e PF01777.13 CBZ29666.1 - 2e-26 91.9 1.4 2.7e-26 91.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CBZ29666.1 - 6.3e-06 25.6 0.6 1.6e-05 24.3 0.4 1.7 1 0 0 1 1 1 1 KOW motif Sybindin PF04099.7 CBZ29667.1 - 3e-22 78.8 0.0 3.5e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CBZ29667.1 - 9.4e-09 35.2 0.0 1.1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Rhodanese PF00581.15 CBZ29669.1 - 2.3e-08 34.3 0.0 2.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Sec7 PF01369.15 CBZ29670.1 - 1.7e-28 99.5 0.0 3e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CBZ29670.1 - 7.9e-14 51.4 0.0 2.2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal MTS PF05175.9 CBZ29671.1 - 0.098 12.0 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain DUF3138 PF11336.3 CBZ29671.1 - 2.5 6.1 10.4 0.26 9.4 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) RNase_T PF00929.19 CBZ29674.1 - 2e-21 76.9 0.1 4.6e-15 56.2 0.0 3.0 1 1 1 2 2 2 2 Exonuclease Cylicin_N PF15241.1 CBZ29675.1 - 0.12 12.2 0.4 0.22 11.4 0.3 1.3 1 0 0 1 1 1 0 Cylicin N-terminus RRM_6 PF14259.1 CBZ29676.1 - 9.7e-22 76.7 0.1 7.2e-10 38.7 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ29676.1 - 1.3e-20 72.7 0.1 8.9e-07 28.4 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ29676.1 - 2.4e-06 27.2 0.1 1.2e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RPN7 PF10602.4 CBZ29677.1 - 9.7e-49 165.1 0.3 1.6e-48 164.3 0.0 1.5 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 CBZ29677.1 - 3.5e-16 59.4 0.4 9e-16 58.0 0.0 1.9 3 0 0 3 3 3 1 PCI domain Prefoldin PF02996.12 CBZ29679.1 - 9.6e-11 41.3 0.3 1.8e-10 40.5 0.2 1.5 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 CBZ29679.1 - 7.8e-06 25.5 2.9 0.00053 19.7 0.2 2.3 2 0 0 2 2 2 2 Prefoldin subunit Chibby PF14645.1 CBZ29679.1 - 0.048 13.5 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Chibby family TPR_11 PF13414.1 CBZ29680.1 - 1.7e-19 69.2 16.8 8.4e-12 44.5 0.4 4.5 4 0 0 4 4 4 3 TPR repeat TPR_16 PF13432.1 CBZ29680.1 - 9.9e-12 45.2 11.9 1.9e-08 34.7 0.6 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat CS PF04969.11 CBZ29680.1 - 1.2e-09 38.5 0.1 4.2e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 CS domain TPR_2 PF07719.12 CBZ29680.1 - 1.1e-07 31.2 22.2 0.055 13.4 0.3 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ29680.1 - 2.4e-07 30.0 18.8 0.12 12.0 0.1 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ29680.1 - 3.1e-07 30.6 10.1 4.1e-05 23.8 0.6 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ29680.1 - 0.0018 18.3 10.1 0.73 10.0 0.2 4.0 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CBZ29680.1 - 0.0029 18.0 25.0 0.16 12.7 0.1 7.4 5 2 2 7 7 7 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CBZ29680.1 - 0.0065 16.3 7.9 0.78 9.6 0.0 4.2 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat DUF4427 PF14468.1 CBZ29680.1 - 0.064 12.9 1.0 13 5.5 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4427) TPR_9 PF13371.1 CBZ29680.1 - 0.1 12.4 10.2 7.8 6.4 0.1 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Phage_lysozyme PF00959.14 CBZ29680.1 - 0.11 12.7 1.2 0.73 10.1 0.1 2.5 2 0 0 2 2 2 0 Phage lysozyme TPR_12 PF13424.1 CBZ29680.1 - 0.12 12.3 23.1 1.7 8.6 0.4 5.6 4 2 1 5 5 5 0 Tetratricopeptide repeat TPPII_N PF12583.3 CBZ29680.1 - 0.15 12.2 0.0 0.15 12.2 0.0 3.1 2 1 0 2 2 2 0 Tripeptidyl peptidase II N terminal TPR_7 PF13176.1 CBZ29680.1 - 1.5 8.7 19.0 17 5.5 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat FYVE PF01363.16 CBZ29681.1 - 0.11 12.4 15.0 0.24 11.3 10.4 1.5 1 0 0 1 1 1 0 FYVE zinc finger CTP_transf_1 PF01148.15 CBZ29682.1 - 5.8e-28 98.2 15.9 7.2e-28 97.9 0.9 3.2 3 1 0 3 3 3 2 Cytidylyltransferase family DUF778 PF05608.7 CBZ29683.1 - 5e-49 165.7 0.0 6.9e-49 165.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF778) SNAP PF14938.1 CBZ29685.1 - 3.7e-54 183.7 18.6 4.3e-54 183.5 12.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CBZ29685.1 - 1.8e-06 27.8 9.0 0.0031 17.4 2.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ29685.1 - 0.00076 19.9 18.7 2.1 9.1 0.2 5.5 3 1 3 6 6 5 3 Tetratricopeptide repeat Foie-gras_1 PF11817.3 CBZ29685.1 - 0.0013 18.3 6.9 0.0064 16.0 2.5 2.1 1 1 1 2 2 2 2 Foie gras liver health family 1 TPR_19 PF14559.1 CBZ29685.1 - 0.0074 16.6 12.6 0.34 11.2 0.6 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ29685.1 - 0.092 12.5 9.3 12 6.0 0.1 5.1 3 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ29685.1 - 0.096 13.3 14.3 1.6 9.5 1.7 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF410 PF04190.8 CBZ29685.1 - 0.11 12.0 5.3 0.18 11.3 0.8 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF410) Apc3 PF12895.2 CBZ29685.1 - 0.11 12.6 5.9 0.14 12.2 1.3 2.7 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBZ29685.1 - 0.16 12.4 14.8 0.8 10.2 0.1 5.5 4 1 2 6 6 6 0 Tetratricopeptide repeat PPR_3 PF13812.1 CBZ29685.1 - 0.28 11.5 5.6 8.1 7.0 0.1 3.7 4 0 0 4 4 4 0 Pentatricopeptide repeat domain DUF1024 PF06260.7 CBZ29685.1 - 0.48 10.6 4.7 16 5.6 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1024) DUF2225 PF09986.4 CBZ29685.1 - 1.4 8.3 9.8 62 2.9 6.8 2.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TRAPPC-Trs85 PF12739.2 CBZ29685.1 - 2.3 6.7 8.6 8.3 4.9 1.3 2.6 1 1 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_4 PF07721.9 CBZ29685.1 - 4.5 8.0 7.8 24 5.7 0.2 4.5 4 1 0 4 4 3 0 Tetratricopeptide repeat APG6 PF04111.7 CBZ29686.1 - 4.5 6.2 37.2 0.091 11.7 4.2 3.6 2 1 0 3 3 3 0 Autophagy protein Apg6 UCH PF00443.24 CBZ29687.1 - 1.7e-51 174.9 0.0 2.8e-51 174.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ29687.1 - 1.8e-20 73.5 0.3 3.8e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase FG-GAP PF01839.18 CBZ29688.1 - 0.00034 20.2 0.1 0.0014 18.2 0.1 2.0 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.1 CBZ29688.1 - 0.015 15.6 0.0 0.084 13.2 0.0 2.3 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 CBZ29688.1 - 0.068 12.6 0.3 0.5 9.7 0.0 2.5 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region PQQ PF01011.16 CBZ29688.1 - 0.073 12.6 1.1 0.51 9.9 0.0 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat BBS2_C PF14782.1 CBZ29688.1 - 0.28 9.7 0.0 0.48 8.9 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal TTL PF03133.10 CBZ29689.1 - 7.1e-68 228.6 0.0 1.4e-55 188.3 0.0 2.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ29689.1 - 5e-05 22.2 0.0 0.01 14.6 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp DUF1738 PF08401.6 CBZ29690.1 - 0.00012 21.8 0.0 4.6 6.9 0.0 3.4 3 0 0 3 3 3 3 Domain of unknown function (DUF1738) NDK PF00334.14 CBZ29691.1 - 7.9e-57 190.8 0.0 9e-57 190.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NDK PF00334.14 CBZ29692.1 - 7.9e-57 190.8 0.0 9e-57 190.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MCM PF00493.18 CBZ29693.1 - 1.9e-126 421.3 0.0 2.6e-126 420.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBZ29693.1 - 9.9e-15 55.1 0.0 2.3e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBZ29693.1 - 5.8e-07 28.8 0.0 8.5e-05 21.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBZ29693.1 - 6.5e-06 25.9 0.0 3.7e-05 23.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CBZ29693.1 - 0.014 15.0 0.0 0.037 13.6 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CBZ29693.1 - 0.1 12.0 0.0 0.77 9.2 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain TBCA PF02970.11 CBZ29694.1 - 2.7e-22 78.6 2.6 3.3e-22 78.3 1.8 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Mnd1 PF03962.10 CBZ29694.1 - 0.089 12.4 1.1 0.1 12.2 0.7 1.1 1 0 0 1 1 1 0 Mnd1 family AAA_30 PF13604.1 CBZ29694.1 - 0.1 12.1 0.2 0.1 12.1 0.1 1.6 2 0 0 2 2 2 0 AAA domain TMF_TATA_bd PF12325.3 CBZ29694.1 - 0.15 11.8 2.7 0.23 11.1 1.3 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Pox_A_type_inc PF04508.7 CBZ29694.1 - 0.36 10.7 4.0 26 4.9 0.0 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Phosducin PF02114.11 CBZ29695.1 - 3.6e-11 42.2 0.1 4.2e-11 42.0 0.1 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 CBZ29695.1 - 2.6e-08 33.4 0.0 3.8e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 CBZ29695.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin domain Adeno_100 PF02438.11 CBZ29695.1 - 0.087 11.0 0.1 0.12 10.6 0.1 1.1 1 0 0 1 1 1 0 Late 100kD protein DIM1 PF02966.11 CBZ29695.1 - 0.18 11.2 1.2 0.43 10.1 0.1 2.0 2 1 0 2 2 2 0 Mitosis protein DIM1 Rab5ip PF07019.7 CBZ29698.1 - 6.9e-21 74.1 4.8 8.3e-21 73.9 3.3 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) FA_desaturase PF00487.19 CBZ29698.1 - 0.3 10.4 2.1 0.39 10.1 1.5 1.3 1 1 0 1 1 1 0 Fatty acid desaturase DUF21 PF01595.15 CBZ29700.1 - 3.3e-29 101.4 7.2 4.9e-29 100.9 5.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CBZ29700.1 - 0.047 13.4 0.3 0.51 10.1 0.0 2.8 3 0 0 3 3 3 0 CBS domain L_HGMIC_fpl PF10242.4 CBZ29700.1 - 0.19 11.7 4.7 0.1 12.6 0.7 2.0 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein LRR_4 PF12799.2 CBZ29701.1 - 4.5e-21 74.0 11.9 2e-08 33.6 0.4 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ29701.1 - 9.3e-09 34.9 7.6 0.00037 20.1 1.9 3.1 1 1 3 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 CBZ29701.1 - 1.5e-05 24.6 0.1 0.00014 21.4 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.1 CBZ29701.1 - 1.9e-05 24.2 8.7 1.8 8.9 0.4 5.5 3 1 2 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 CBZ29701.1 - 3.8e-05 23.1 6.9 2 8.7 0.1 6.0 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 CBZ29701.1 - 0.00082 19.1 3.6 1.9 9.0 0.1 5.1 5 0 0 5 5 5 1 Leucine rich repeat MMR_HSR1 PF01926.18 CBZ29702.1 - 4e-11 42.9 0.0 8.9e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBZ29702.1 - 7.5e-06 25.2 0.0 2.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBZ29702.1 - 0.0016 17.8 0.0 0.4 10.1 0.0 2.7 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CBZ29702.1 - 0.013 15.4 2.0 0.023 14.6 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 CBZ29702.1 - 0.018 15.3 0.1 0.084 13.1 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Miro PF08477.8 CBZ29702.1 - 0.031 14.7 0.3 0.16 12.4 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 CBZ29702.1 - 0.16 12.1 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.10 CBZ29702.1 - 0.2 10.2 0.0 1 7.8 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein DnaJ PF00226.26 CBZ29703.1 - 2.5e-20 71.9 0.0 5.3e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Angiomotin_C PF12240.3 CBZ29703.1 - 0.16 11.4 7.2 0.4 10.1 5.0 1.7 1 1 0 1 1 1 0 Angiomotin C terminal Metallophos PF00149.23 CBZ29704.1 - 8.2e-43 146.1 0.1 1e-42 145.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ras PF00071.17 CBZ29705.1 - 3.5e-11 42.7 0.1 7.8e-11 41.6 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CBZ29705.1 - 7.5e-06 26.4 0.0 1.6e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CBZ29705.1 - 0.00011 21.4 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region IBR PF01485.16 CBZ29705.1 - 0.00022 21.0 0.1 0.00048 19.9 0.1 1.5 1 0 0 1 1 1 1 IBR domain YdjO PF14169.1 CBZ29705.1 - 0.0064 15.9 0.2 0.014 14.8 0.2 1.5 1 0 0 1 1 1 1 Cold-inducible protein YdjO Zn_Tnp_IS1 PF03811.8 CBZ29705.1 - 0.046 13.2 0.1 0.15 11.6 0.1 1.9 1 0 0 1 1 1 0 InsA N-terminal domain PduV-EutP PF10662.4 CBZ29705.1 - 0.17 11.3 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation zf-AN1 PF01428.11 CBZ29705.1 - 9.2 6.2 6.7 22 5.0 0.3 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger zf-MIZ PF02891.15 CBZ29708.1 - 3.1e-10 39.4 6.5 6.1e-10 38.4 4.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CBZ29708.1 - 1.4e-05 24.4 1.6 3.2e-05 23.3 1.1 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF2072 PF09845.4 CBZ29708.1 - 0.065 13.1 0.8 0.46 10.4 0.2 2.3 2 0 0 2 2 2 0 Zn-ribbon containing protein (DUF2072) DZR PF12773.2 CBZ29708.1 - 0.19 11.5 0.2 0.19 11.5 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon RRN7 PF11781.3 CBZ29708.1 - 1.1 8.7 9.0 5.5 6.5 0.1 3.0 2 1 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-NADH-PPase PF09297.6 CBZ29708.1 - 1.3 8.6 9.6 0.17 11.4 3.0 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain OrfB_Zn_ribbon PF07282.6 CBZ29708.1 - 1.4 8.5 3.9 1.3 8.7 1.1 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_Tnp_IS91 PF14319.1 CBZ29708.1 - 1.8 8.1 6.1 3.8 7.0 0.3 2.4 2 0 0 2 2 2 0 Transposase zinc-binding domain ABC_tran PF00005.22 CBZ29709.1 - 2.8e-34 118.3 0.0 1.3e-33 116.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 CBZ29709.1 - 7.7e-24 84.5 7.3 9.8e-24 84.2 5.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CBZ29709.1 - 1.5e-05 25.1 0.0 0.0092 15.9 0.0 2.6 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 CBZ29709.1 - 2.1e-05 23.9 0.3 0.0036 16.5 0.2 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBZ29709.1 - 0.00066 19.1 1.6 0.0021 17.5 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Pox_A31 PF05771.6 CBZ29709.1 - 0.0036 17.0 0.2 0.0086 15.8 0.1 1.6 1 0 0 1 1 1 1 Poxvirus A31 protein AAA_22 PF13401.1 CBZ29709.1 - 0.0046 17.1 0.1 0.051 13.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ29709.1 - 0.0085 16.0 0.1 0.018 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CBZ29709.1 - 0.0097 15.1 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBZ29709.1 - 0.01 16.6 0.0 0.027 15.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBZ29709.1 - 0.022 15.0 0.1 0.38 11.0 0.0 2.7 2 1 1 3 3 3 0 AAA domain AAA_33 PF13671.1 CBZ29709.1 - 0.023 14.5 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CBZ29709.1 - 0.026 14.8 0.6 0.17 12.1 0.2 2.1 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 CBZ29709.1 - 0.034 13.8 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CBZ29709.1 - 0.099 12.6 0.0 0.43 10.5 0.0 2.1 3 0 0 3 3 2 0 50S ribosome-binding GTPase FSH1 PF03959.8 CBZ29712.1 - 4.5e-29 101.4 0.0 7e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MMR_HSR1_C PF08438.5 CBZ29712.1 - 1.3e-26 92.9 0.0 4.5e-26 91.2 0.0 1.9 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 CBZ29712.1 - 4.3e-14 52.4 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RWD PF05773.17 CBZ29712.1 - 6.9e-05 22.7 0.0 0.00017 21.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain Abhydrolase_5 PF12695.2 CBZ29712.1 - 0.00025 20.7 0.3 0.00025 20.7 0.2 2.6 3 1 1 4 4 4 1 Alpha/beta hydrolase family FeoB_N PF02421.13 CBZ29712.1 - 0.00063 19.0 0.1 0.0063 15.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Cutinase PF01083.17 CBZ29712.1 - 0.0087 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Cutinase ArgK PF03308.11 CBZ29712.1 - 0.058 12.1 0.1 0.27 9.9 0.0 1.9 2 0 0 2 2 2 0 ArgK protein ATP_bind_1 PF03029.12 CBZ29712.1 - 0.07 12.6 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ribosomal_L3 PF00297.17 CBZ29713.1 - 2.7e-99 331.8 9.6 3.3e-99 331.5 6.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Aldedh PF00171.17 CBZ29714.1 - 1.1e-17 63.5 1.2 2.3e-13 49.2 0.1 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family YadA_anchor PF03895.10 CBZ29714.1 - 0.4 10.7 5.9 0.44 10.5 0.2 3.3 3 0 0 3 3 3 0 YadA-like C-terminal region IQ PF00612.22 CBZ29715.1 - 5.9e-25 84.4 110.6 2.7e-05 23.4 2.8 13.3 12 0 0 12 12 12 12 IQ calmodulin-binding motif LRR_4 PF12799.2 CBZ29716.1 - 1.6e-09 37.2 0.6 7.2e-07 28.6 0.6 3.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBZ29716.1 - 3.9e-08 32.5 3.1 0.0017 18.2 0.2 4.1 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 CBZ29716.1 - 7.1e-05 22.3 0.3 0.35 11.0 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.1 CBZ29716.1 - 0.0048 16.6 0.9 0.015 15.0 0.6 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_7 PF13504.1 CBZ29716.1 - 0.0049 16.8 1.7 4 8.0 0.1 4.6 4 0 0 4 4 4 1 Leucine rich repeat L51_S25_CI-B8 PF05047.11 CBZ29717.1 - 0.0056 16.3 0.1 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF2738 PF10927.3 CBZ29717.1 - 0.04 12.9 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) COG5 PF10392.4 CBZ29719.1 - 3.5e-15 56.1 18.5 4.9e-13 49.1 3.2 3.8 2 1 1 3 3 3 2 Golgi transport complex subunit 5 DUF1664 PF07889.7 CBZ29719.1 - 0.0036 17.0 2.5 0.005 16.6 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) COG2 PF06148.6 CBZ29719.1 - 1 9.2 5.5 1.5 8.6 2.3 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PRT_C PF08372.5 CBZ29720.1 - 0.13 11.8 0.5 0.72 9.3 0.0 2.1 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Arf PF00025.16 CBZ29721.1 - 1e-05 24.8 0.2 0.00083 18.6 0.1 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CBZ29721.1 - 1.3e-05 25.1 0.1 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ29721.1 - 3.9e-05 24.1 0.0 6.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CBZ29721.1 - 7.6e-05 22.1 0.0 0.00027 20.3 0.0 1.8 2 1 0 2 2 2 1 Ras family GTP_EFTU PF00009.22 CBZ29721.1 - 0.00059 19.3 0.0 0.00092 18.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CBZ29721.1 - 0.001 17.8 0.1 0.52 8.9 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit AAA_17 PF13207.1 CBZ29721.1 - 0.0015 19.3 0.0 0.0031 18.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CBZ29721.1 - 0.0047 16.4 0.0 0.009 15.5 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CBZ29721.1 - 0.03 13.5 0.2 0.048 12.8 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 CBZ29721.1 - 0.085 12.6 0.2 0.21 11.3 0.1 1.6 1 1 1 2 2 2 0 Dynamin family AAA_18 PF13238.1 CBZ29721.1 - 0.096 12.9 0.1 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 CBZ29721.1 - 0.13 11.3 0.0 0.85 8.7 0.0 2.2 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Septin PF00735.13 CBZ29721.1 - 0.14 11.1 0.1 0.2 10.6 0.1 1.2 1 0 0 1 1 1 0 Septin T2SE PF00437.15 CBZ29721.1 - 0.14 11.0 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 CBZ29723.1 - 3.6e-06 27.1 0.1 8.4e-06 25.8 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CBZ29723.1 - 1.9e-05 24.8 0.2 0.0035 17.4 0.1 2.7 2 2 0 2 2 2 1 AAA domain G-alpha PF00503.15 CBZ29723.1 - 5.9e-05 21.9 0.1 0.0015 17.3 0.2 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Miro PF08477.8 CBZ29723.1 - 6.3e-05 23.4 0.0 0.0009 19.7 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 CBZ29723.1 - 0.00015 20.9 0.0 0.00031 19.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBZ29723.1 - 0.00038 19.9 0.0 1.1 8.6 0.0 2.6 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain NACHT PF05729.7 CBZ29723.1 - 0.00089 18.9 0.0 0.0031 17.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 CBZ29723.1 - 0.0028 17.9 0.1 0.0051 17.1 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CBZ29723.1 - 0.0031 17.0 0.1 0.007 15.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CBZ29723.1 - 0.0033 16.5 0.1 0.028 13.5 0.0 2.1 1 1 1 2 2 2 1 Zeta toxin cobW PF02492.14 CBZ29723.1 - 0.0038 16.6 0.3 0.038 13.4 0.2 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 CBZ29723.1 - 0.0043 16.6 0.6 0.22 11.0 0.3 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 CBZ29723.1 - 0.0056 16.4 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CBZ29723.1 - 0.012 15.5 1.2 0.056 13.3 0.8 2.2 1 1 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 CBZ29723.1 - 0.013 14.8 0.0 0.04 13.1 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 CBZ29723.1 - 0.019 14.4 0.1 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.1 CBZ29723.1 - 0.023 14.2 0.2 0.78 9.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 CBZ29723.1 - 0.025 13.4 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 CBZ29723.1 - 0.031 13.1 0.1 0.06 12.2 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 CBZ29723.1 - 0.032 13.9 0.0 0.069 12.8 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase Arf PF00025.16 CBZ29723.1 - 0.039 13.1 0.0 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family MobB PF03205.9 CBZ29723.1 - 0.042 13.5 0.1 0.097 12.3 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 CBZ29723.1 - 0.051 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Ras PF00071.17 CBZ29723.1 - 0.065 12.6 0.0 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 Ras family DAP3 PF10236.4 CBZ29723.1 - 0.067 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Septin PF00735.13 CBZ29723.1 - 0.088 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_17 PF13207.1 CBZ29723.1 - 0.091 13.5 0.1 0.33 11.7 0.1 1.9 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 CBZ29723.1 - 0.091 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 CBZ29723.1 - 0.094 12.6 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CBZ29723.1 - 0.098 12.0 0.2 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain PIF1 PF05970.9 CBZ29723.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Pkinase PF00069.20 CBZ29725.1 - 3.2e-73 246.0 0.0 5.2e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29725.1 - 3.6e-35 121.3 0.0 1.4e-34 119.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ29725.1 - 0.00089 18.2 0.0 0.002 17.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CBZ29725.1 - 0.0018 17.6 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 CBZ29725.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glucosamine_iso PF01182.15 CBZ29726.1 - 1.6e-22 80.2 0.0 2.2e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Cpn60_TCP1 PF00118.19 CBZ29727.1 - 2e-135 452.1 7.3 2.3e-135 451.9 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Se-cys_synth_N PF12390.3 CBZ29728.1 - 0.017 15.2 0.3 0.22 11.6 0.1 2.9 2 1 0 2 2 2 0 Selenocysteine synthase N terminal CTDII PF01556.13 CBZ29730.1 - 4.4e-22 77.7 0.0 1.3e-20 73.0 0.0 2.5 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.26 CBZ29730.1 - 1.1e-17 63.4 5.6 1.8e-17 62.7 3.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CBZ29730.1 - 2.4e-12 46.6 13.8 4.2e-12 45.9 9.6 1.4 1 0 0 1 1 1 1 DnaJ central domain PRAP PF15314.1 CBZ29730.1 - 0.028 14.6 0.9 0.42 10.9 0.1 2.4 2 0 0 2 2 2 0 Proline-rich acidic protein 1, pregnancy-specific uterine Arabinose_Isome PF02610.10 CBZ29730.1 - 0.17 10.8 0.2 0.24 10.3 0.1 1.1 1 0 0 1 1 1 0 L-arabinose isomerase DZR PF12773.2 CBZ29730.1 - 0.67 9.8 11.6 7.9 6.3 8.0 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF3797 PF12677.2 CBZ29730.1 - 0.89 9.2 9.0 12 5.6 0.4 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3797) Pyr_redox_2 PF07992.9 CBZ29731.1 - 1.3e-41 142.7 4.1 1.4e-41 142.6 1.8 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CBZ29731.1 - 2.9e-39 133.5 0.4 6.9e-39 132.2 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CBZ29731.1 - 6.5e-20 71.3 10.1 4e-18 65.5 0.9 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBZ29731.1 - 6.4e-13 48.3 3.4 7.4e-11 41.5 0.2 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 CBZ29731.1 - 5e-10 39.0 1.3 5e-10 39.0 0.9 2.8 3 1 1 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CBZ29731.1 - 7.4e-10 39.2 0.6 1.7e-06 28.2 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ29731.1 - 4.7e-07 29.7 6.7 0.00011 22.1 0.6 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CBZ29731.1 - 6.6e-07 28.5 1.4 6.6e-07 28.5 1.0 3.6 2 1 2 4 4 4 1 FAD binding domain Thi4 PF01946.12 CBZ29731.1 - 2e-06 27.0 4.9 2.2e-05 23.7 0.5 2.8 1 1 1 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 CBZ29731.1 - 9.2e-06 24.9 12.8 0.031 13.3 0.4 3.2 2 1 1 3 3 3 3 FAD binding domain K_oxygenase PF13434.1 CBZ29731.1 - 2.5e-05 23.3 0.3 0.013 14.4 0.0 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 CBZ29731.1 - 0.00034 19.2 1.3 0.00034 19.2 0.9 3.6 3 1 1 4 4 4 1 HI0933-like protein DAO PF01266.19 CBZ29731.1 - 0.00089 18.2 20.4 0.062 12.1 1.6 4.1 2 2 1 4 4 4 3 FAD dependent oxidoreductase 3HCDH_N PF02737.13 CBZ29731.1 - 0.0014 18.3 0.8 0.0014 18.3 0.5 2.8 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CBZ29731.1 - 0.013 15.0 2.5 0.23 11.0 0.1 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 CBZ29731.1 - 0.028 14.7 0.1 0.55 10.5 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 CBZ29731.1 - 0.5 10.6 4.9 1.6 9.0 0.7 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 CBZ29731.1 - 1.4 7.7 6.6 2.6 6.8 0.4 3.0 2 1 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 CBZ29731.1 - 1.9 7.8 6.0 0.56 9.5 0.5 2.6 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cyclin_N PF00134.18 CBZ29732.1 - 1.4e-38 131.2 3.1 1.7e-38 131.0 0.8 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CBZ29732.1 - 4.4e-34 116.9 0.2 1.2e-33 115.5 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF221 PF02714.10 CBZ29733.1 - 0.07 11.9 0.1 0.088 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF221 Na_H_antiporter PF03553.9 CBZ29733.1 - 0.074 12.0 0.0 0.084 11.8 0.0 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter family CH PF00307.26 CBZ29734.1 - 0.044 13.8 0.1 6.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Calponin homology (CH) domain zf-B_box PF00643.19 CBZ29735.1 - 1.3e-06 28.1 3.4 3.3e-06 26.8 2.3 1.7 1 0 0 1 1 1 1 B-box zinc finger Lipase_3 PF01764.20 CBZ29736.1 - 5.4e-11 42.2 0.0 2.7e-10 39.9 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) Voltage_CLC PF00654.15 CBZ29737.1 - 1.4e-76 257.8 24.3 1.4e-76 257.8 16.9 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CBZ29737.1 - 1.6e-09 37.4 0.7 0.00012 21.7 0.1 2.5 2 0 0 2 2 2 2 CBS domain KRTDAP PF15200.1 CBZ29737.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Keratinocyte differentiation-associated TruD PF01142.13 CBZ29738.1 - 5.2e-32 110.9 0.0 1e-14 54.0 0.0 3.2 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Gb3_synth PF04572.7 CBZ29738.1 - 0.086 12.5 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region zf-MYND PF01753.13 CBZ29739.1 - 0.0023 17.7 13.0 0.0023 17.7 9.0 2.5 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 CBZ29739.1 - 0.16 11.8 10.1 0.13 12.1 5.3 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Abhydrolase_6 PF12697.2 CBZ29740.1 - 3.8e-05 23.6 1.3 9.2e-05 22.4 0.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ29740.1 - 0.00016 21.2 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Dopey_N PF04118.9 CBZ29741.1 - 1.8e-26 92.6 0.0 3.7e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 Dopey, N-terminal Cytochrom_B_N_2 PF13631.1 CBZ29742.1 - 3.6 7.3 9.0 3.5 7.3 0.4 2.7 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB UPF0564 PF10595.4 CBZ29743.1 - 9e-12 44.5 15.6 3.9e-09 35.8 0.8 2.9 3 1 0 3 3 3 2 Uncharacterised protein family UPF0564 DUF4071 PF13281.1 CBZ29743.1 - 0.083 11.7 1.8 0.15 10.8 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) UPF0564 PF10595.4 CBZ29744.1 - 7.7e-12 44.7 15.8 5.3e-09 35.4 1.4 2.7 3 0 0 3 3 3 2 Uncharacterised protein family UPF0564 DUF4071 PF13281.1 CBZ29744.1 - 0.074 11.8 1.8 0.12 11.1 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) RE_HindIII PF09518.5 CBZ29744.1 - 0.14 11.0 0.3 0.24 10.2 0.2 1.3 1 0 0 1 1 1 0 HindIII restriction endonuclease zf-C2HC_2 PF13913.1 CBZ29746.1 - 4.5e-25 86.7 14.2 1.1e-09 37.7 0.4 3.5 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-ribbon_3 PF13248.1 CBZ29746.1 - 0.00023 20.2 17.8 0.03 13.5 5.7 3.9 3 1 1 4 4 4 2 zinc-ribbon domain Sgf11 PF08209.6 CBZ29746.1 - 0.014 14.7 5.7 0.41 9.9 0.1 3.5 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_2 PF13240.1 CBZ29746.1 - 0.015 14.7 25.2 0.27 10.7 7.6 4.3 4 1 1 5 5 5 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 CBZ29746.1 - 0.086 13.1 4.0 15 6.0 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-CHCC PF10276.4 CBZ29746.1 - 0.11 12.3 3.3 1.6 8.6 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2 PF00096.21 CBZ29746.1 - 0.16 12.3 0.3 0.16 12.3 0.2 4.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type DZR PF12773.2 CBZ29746.1 - 0.21 11.4 19.1 5.2 6.9 9.4 3.8 3 1 0 3 3 3 0 Double zinc ribbon NOB1_Zn_bind PF08772.6 CBZ29746.1 - 1.7 8.5 8.6 14 5.5 4.6 2.8 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF164 PF02591.10 CBZ29746.1 - 3 7.7 8.4 9.7 6.1 0.0 3.6 3 1 0 3 3 3 0 Putative zinc ribbon domain RNase_PH PF01138.16 CBZ29747.1 - 1.2e-06 28.8 0.0 5.4e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CBZ29747.1 - 2.2e-06 27.5 0.0 3.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RRM_1 PF00076.17 CBZ29748.1 - 6.7e-09 35.2 0.0 4.1e-06 26.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ29748.1 - 1.2e-06 28.3 0.0 0.00011 22.0 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ29748.1 - 7.2e-05 22.5 0.0 0.0002 21.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mcm10 PF09332.6 CBZ29748.1 - 0.2 10.9 3.9 0.35 10.1 2.7 1.3 1 0 0 1 1 1 0 Mcm10 replication factor TPR_11 PF13414.1 CBZ29749.1 - 0.017 14.7 5.1 0.13 11.9 0.1 3.8 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.1 CBZ29749.1 - 0.91 10.2 0.0 0.3 11.8 0.3 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat DEAD PF00270.24 CBZ29750.1 - 8.2e-17 61.2 0.0 1.8e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ29750.1 - 7.7e-07 28.8 0.0 2.9e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ29750.1 - 0.00066 19.5 0.0 0.0026 17.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CBZ29750.1 - 0.0042 17.2 0.6 0.19 11.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 CBZ29750.1 - 0.011 15.8 0.0 0.44 10.7 0.0 3.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CBZ29750.1 - 0.03 13.7 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.11 CBZ29750.1 - 0.036 13.3 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NAD_binding_7 PF13241.1 CBZ29750.1 - 0.042 14.0 0.0 0.26 11.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Cytochrome_CBB3 PF13442.1 CBZ29752.1 - 0.086 13.0 0.4 4.2 7.5 0.0 3.1 2 1 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III Robl_LC7 PF03259.12 CBZ29753.1 - 4e-09 35.9 0.1 1.7e-07 30.6 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Nol1_Nop2_Fmu PF01189.12 CBZ29755.1 - 0.066 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 NOL1/NOP2/sun family UPF0104 PF03706.8 CBZ29756.1 - 0.047 12.9 1.1 0.058 12.6 0.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) YMF19 PF02326.10 CBZ29756.1 - 0.26 11.9 1.2 0.34 11.5 0.8 1.3 1 1 0 1 1 1 0 Plant ATP synthase F0 MAP65_ASE1 PF03999.7 CBZ29757.1 - 0.009 14.6 0.2 0.014 14.0 0.1 1.4 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) AIP3 PF03915.8 CBZ29757.1 - 0.034 13.0 2.7 0.12 11.2 1.8 1.8 1 1 0 1 1 1 0 Actin interacting protein 3 Glu_cyclase_2 PF05096.7 CBZ29757.1 - 0.086 11.8 0.1 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Glutamine cyclotransferase InvH PF04741.7 CBZ29757.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein CDC37_N PF03234.9 CBZ29757.1 - 0.13 12.6 1.5 0.17 12.1 0.5 1.6 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding RYDR_ITPR PF01365.16 CBZ29757.1 - 0.27 10.4 2.8 0.54 9.4 1.9 1.7 1 1 0 1 1 1 0 RIH domain Prefoldin PF02996.12 CBZ29757.1 - 0.55 9.8 6.8 7.6 6.2 0.0 3.3 3 1 1 4 4 4 0 Prefoldin subunit DUF607 PF04678.8 CBZ29757.1 - 0.99 9.2 6.5 7.9 6.3 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function, DUF607 PH PF00169.24 CBZ29759.1 - 0.024 14.8 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 PH domain FAP PF07174.6 CBZ29759.1 - 0.04 13.2 7.3 0.058 12.6 5.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF2360 PF10152.4 CBZ29759.1 - 3.4 7.9 5.0 6.7 6.9 3.5 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF503 PF04456.7 CBZ29760.1 - 0.029 13.9 0.1 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF503) ECH_C PF13766.1 CBZ29762.1 - 6.5e-24 84.3 0.0 8e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH_C PF13766.1 CBZ29763.1 - 1.3e-29 102.7 0.1 2e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CBZ29763.1 - 4.8e-24 84.8 0.0 6.4e-24 84.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family zf-ribbon_3 PF13248.1 CBZ29764.1 - 0.0009 18.3 0.7 0.0022 17.1 0.5 1.7 1 0 0 1 1 1 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CBZ29764.1 - 0.03 13.8 0.8 0.062 12.8 0.6 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 CBZ29764.1 - 0.038 13.8 0.5 0.092 12.5 0.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon BT1 PF03092.11 CBZ29767.1 - 1.5e-28 99.6 22.2 2.3e-28 99.1 15.4 1.1 1 0 0 1 1 1 1 BT1 family TMEM18 PF14770.1 CBZ29768.1 - 1.2e-28 99.1 0.7 1.4e-28 98.8 0.5 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 DUF3733 PF12534.3 CBZ29768.1 - 1.1 8.6 3.2 0.43 9.9 0.1 1.8 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 TYW3 PF02676.9 CBZ29770.1 - 8.5e-34 116.4 0.0 1e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF3813 PF12758.2 CBZ29772.1 - 2.3 8.3 5.4 0.81 9.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3813) MAT_Alpha1 PF04769.7 CBZ29773.1 - 0.00068 19.0 1.1 0.00081 18.7 0.8 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 CKS PF01111.14 CBZ29774.1 - 8.3e-39 131.2 0.9 1e-38 130.9 0.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit TPR_11 PF13414.1 CBZ29775.1 - 1.5e-07 30.9 2.7 0.00013 21.5 0.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBZ29775.1 - 8.8e-07 28.2 0.9 0.062 12.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ29775.1 - 8.9e-06 25.5 2.5 0.1 12.5 0.7 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ29775.1 - 2.6e-05 23.8 8.3 0.051 13.4 0.1 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ29775.1 - 0.007 16.0 0.2 1.1 9.2 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ29775.1 - 0.14 12.0 3.7 2.7 7.9 1.2 3.0 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ29775.1 - 0.49 10.9 7.2 9.3 6.9 0.2 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat SHQ1 PF04925.10 CBZ29776.1 - 3.8e-52 176.4 0.1 8.8e-52 175.3 0.0 1.5 2 0 0 2 2 2 1 SHQ1 protein WD40 PF00400.27 CBZ29777.1 - 0.017 15.0 4.2 6.1 6.9 0.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat Pox_P21 PF05313.7 CBZ29778.1 - 0.00035 19.8 0.5 0.00035 19.8 0.3 2.1 2 1 0 2 2 2 1 Poxvirus P21 membrane protein Cornichon PF03311.9 CBZ29778.1 - 0.00055 20.0 7.7 0.00055 20.0 5.4 1.4 2 0 0 2 2 2 1 Cornichon protein Tic20 PF09685.5 CBZ29778.1 - 0.41 10.6 13.3 1.8 8.5 1.4 2.2 2 0 0 2 2 2 0 Tic20-like protein Chromate_transp PF02417.10 CBZ29778.1 - 1.9 8.0 13.1 0.23 11.0 4.6 2.4 1 1 2 3 3 3 0 Chromate transporter DUF4064 PF13273.1 CBZ29778.1 - 3.9 7.6 11.0 0.1 12.6 0.5 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF4064) Cornichon PF03311.9 CBZ29779.1 - 2.4e-14 53.5 2.6 2.4e-14 53.5 1.8 1.5 1 1 0 1 1 1 1 Cornichon protein FeoB_C PF07664.7 CBZ29779.1 - 0.1 11.9 2.5 0.25 10.7 1.8 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B C terminus Herpes_BLRF2 PF05812.7 CBZ29780.1 - 0.0016 18.2 0.9 0.045 13.5 1.4 2.5 3 0 0 3 3 2 1 Herpesvirus BLRF2 protein MUG113 PF13455.1 CBZ29780.1 - 0.012 16.0 1.6 0.53 10.7 0.0 2.3 2 0 0 2 2 2 0 Meiotically up-regulated gene 113 bZIP_1 PF00170.16 CBZ29780.1 - 0.022 14.7 0.8 0.022 14.7 0.5 2.4 2 1 0 2 2 2 0 bZIP transcription factor CENP-Q PF13094.1 CBZ29780.1 - 0.024 14.6 13.4 0.12 12.4 1.5 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Mod_r PF07200.8 CBZ29780.1 - 0.095 12.6 9.1 0.15 11.9 1.8 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IncA PF04156.9 CBZ29780.1 - 0.16 11.5 11.3 0.51 9.9 1.0 2.2 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 CBZ29780.1 - 0.23 10.9 2.3 1 8.8 0.4 2.5 2 0 0 2 2 2 0 Septum formation initiator GrpE PF01025.14 CBZ29780.1 - 0.39 10.2 3.9 5.1 6.6 1.0 2.3 2 0 0 2 2 2 0 GrpE Exonuc_VII_S PF02609.11 CBZ29780.1 - 0.69 9.7 5.6 0.75 9.6 0.7 2.8 3 0 0 3 3 3 0 Exonuclease VII small subunit APG6 PF04111.7 CBZ29780.1 - 1.4 7.8 9.7 0.42 9.6 1.8 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 HALZ PF02183.13 CBZ29780.1 - 1.9 8.2 5.4 5.9 6.6 0.7 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper GTPase_Cys_C PF12631.2 CBZ29780.1 - 3.1 8.2 6.3 3.8 7.9 0.2 2.8 2 1 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE HAUS-augmin3 PF14932.1 CBZ29780.1 - 3.3 6.8 8.9 1.9 7.5 0.8 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1192 PF06698.6 CBZ29780.1 - 3.5 7.5 8.9 4 7.3 0.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) NYD-SP28_assoc PF14775.1 CBZ29780.1 - 4 7.2 10.0 0.39 10.4 0.8 3.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain Jnk-SapK_ap_N PF09744.4 CBZ29780.1 - 5.5 6.9 10.2 1.1 9.2 0.7 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 T5orf172 PF10544.4 CBZ29780.1 - 7.2 7.0 5.9 11 6.5 0.9 2.4 2 1 0 2 2 2 0 T5orf172 domain Atg14 PF10186.4 CBZ29780.1 - 9.2 5.1 11.7 1.8 7.3 3.2 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Myosin_head PF00063.16 CBZ29782.1 - 5.8e-170 566.6 0.1 1.9e-169 564.9 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) UBA PF00627.26 CBZ29782.1 - 7.6e-08 31.9 4.3 7.5e-05 22.4 0.7 3.2 3 0 0 3 3 3 2 UBA/TS-N domain AAA_22 PF13401.1 CBZ29782.1 - 0.003 17.6 0.1 0.018 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.14 CBZ29782.1 - 0.0049 16.5 0.5 0.013 15.1 0.3 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Mg_chelatase PF01078.16 CBZ29782.1 - 0.025 13.7 0.0 0.082 12.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBZ29782.1 - 0.14 12.0 1.9 0.31 10.9 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain DUF3306 PF11748.3 CBZ29782.1 - 1.8 9.2 7.5 10 6.7 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3306) Peptidase_C54 PF03416.14 CBZ29784.1 - 3.4e-46 157.6 0.0 4.6e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 TPP_enzyme_M PF00205.17 CBZ29784.1 - 0.12 12.1 0.1 7.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Ribosomal_L2_C PF03947.13 CBZ29785.1 - 5.4e-40 136.1 2.2 6.2e-40 136.0 0.8 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBZ29785.1 - 4.6e-13 48.9 0.0 1.5e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain COPIIcoated_ERV PF07970.7 CBZ29786.1 - 3.8e-37 128.0 0.2 5.2e-37 127.6 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CBZ29786.1 - 2.9e-23 81.6 0.2 5.1e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ResIII PF04851.10 CBZ29787.1 - 1.8e-12 47.5 0.0 3.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CBZ29787.1 - 2.6e-11 43.2 0.1 7.8e-11 41.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.1 CBZ29787.1 - 1.2e-10 41.2 0.2 2.7e-10 40.1 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CBZ29787.1 - 4e-07 29.1 0.0 1.8e-06 26.9 0.0 2.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain DEAD PF00270.24 CBZ29787.1 - 0.057 12.9 0.0 0.86 9.0 0.0 2.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase HECT PF00632.20 CBZ29788.1 - 3.6e-43 147.9 0.1 8.8e-43 146.6 0.1 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CBZ29788.1 - 1.3e-26 93.1 0.0 1.1e-07 31.9 0.0 4.5 4 0 0 4 4 4 4 SPRY domain ZZ PF00569.12 CBZ29788.1 - 0.0095 15.4 9.6 0.024 14.1 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type Cullin PF00888.17 CBZ29788.1 - 2.1 6.8 0.1 8.4 4.7 0.0 1.8 2 0 0 2 2 2 0 Cullin family PIN_4 PF13638.1 CBZ29789.1 - 0.00056 20.0 0.0 0.0021 18.1 0.0 2.0 1 1 0 1 1 1 1 PIN domain cNMP_binding PF00027.24 CBZ29792.1 - 3.8e-21 74.7 0.4 3.9e-08 33.0 0.0 4.0 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Gar1 PF04410.9 CBZ29793.1 - 1.3e-23 83.1 0.0 1.7e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Glycos_transf_2 PF00535.21 CBZ29794.1 - 1.1e-07 31.6 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 LysM PF01476.15 CBZ29795.1 - 4e-10 39.4 0.1 0.00038 20.2 0.0 3.3 3 0 0 3 3 3 2 LysM domain HTH_23 PF13384.1 CBZ29795.1 - 0.00068 19.2 0.0 2.2 8.0 0.0 3.4 3 0 0 3 3 3 2 Homeodomain-like domain DUF3606 PF12244.3 CBZ29795.1 - 0.025 14.2 0.4 0.98 9.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) HTH_3 PF01381.17 CBZ29795.1 - 0.028 14.2 0.0 0.88 9.4 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix Fringe PF02434.11 CBZ29795.1 - 0.041 13.1 0.1 0.075 12.2 0.1 1.4 1 0 0 1 1 1 0 Fringe-like Death PF00531.17 CBZ29795.1 - 0.083 12.6 0.1 5.1 6.9 0.0 3.3 4 0 0 4 4 4 0 Death domain HTH_AsnC-type PF13404.1 CBZ29795.1 - 0.35 10.4 5.8 4 7.0 0.0 3.8 4 0 0 4 4 4 0 AsnC-type helix-turn-helix domain Herpes_UL52 PF03121.10 CBZ29797.1 - 1.5e-15 56.6 0.1 6.3e-15 54.6 0.1 2.2 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Ribonucleas_3_3 PF14622.1 CBZ29798.1 - 0.052 13.5 0.0 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease-III-like FOP_dimer PF09398.5 CBZ29799.1 - 0.0047 16.8 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 FOP N terminal dimerisation domain WD40 PF00400.27 CBZ29800.1 - 4e-43 143.8 11.3 5.5e-09 35.5 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_2 PF13360.1 CBZ29800.1 - 7.8e-05 22.2 0.1 0.00089 18.7 0.0 2.1 1 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 CBZ29800.1 - 0.0031 15.7 0.3 0.0057 14.8 0.2 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PQQ PF01011.16 CBZ29800.1 - 0.0062 16.0 0.0 3.9 7.1 0.0 2.7 2 0 0 2 2 2 2 PQQ enzyme repeat DUF4613 PF15390.1 CBZ29800.1 - 0.019 13.1 0.2 0.028 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) PQQ_3 PF13570.1 CBZ29800.1 - 0.022 15.0 0.1 6.3 7.2 0.0 3.2 2 0 0 2 2 2 0 PQQ-like domain DUF3312 PF11768.3 CBZ29800.1 - 0.052 11.7 0.0 0.21 9.7 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) HEAT PF02985.17 CBZ29801.1 - 4.8e-07 29.3 0.5 0.014 15.4 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat UVR PF02151.14 CBZ29801.1 - 2.5e-06 26.7 5.0 0.0029 17.0 0.2 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif HEAT_2 PF13646.1 CBZ29801.1 - 0.012 15.8 1.7 1.5 9.1 0.0 3.3 2 1 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.1 CBZ29801.1 - 0.032 14.7 0.9 3 8.4 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat RecX PF02631.11 CBZ29802.1 - 0.066 13.4 1.6 0.12 12.6 1.1 1.3 1 0 0 1 1 1 0 RecX family DUF1675 PF07897.6 CBZ29802.1 - 0.072 12.9 0.9 0.088 12.6 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) TPR_14 PF13428.1 CBZ29803.1 - 0.071 13.7 1.3 0.39 11.4 0.4 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Zip PF02535.17 CBZ29804.1 - 6.1e-11 41.8 17.8 3.6e-07 29.5 0.7 3.1 2 1 1 3 3 3 3 ZIP Zinc transporter CEP19 PF14933.1 CBZ29807.1 - 3.3e-48 163.9 0.0 5.1e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 CEP19-like protein Nop PF01798.13 CBZ29808.1 - 6.5e-17 61.2 0.0 9.8e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CBZ29808.1 - 1.3e-14 53.7 0.1 2.4e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain Ank_2 PF12796.2 CBZ29809.1 - 8.9e-19 67.6 2.8 7.5e-10 39.0 0.3 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ29809.1 - 3.9e-07 29.5 9.0 7.1e-07 28.7 0.5 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 CBZ29809.1 - 2.4e-06 27.9 0.1 0.00045 20.6 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ29809.1 - 1.3e-05 24.9 0.3 0.01 15.9 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CBZ29809.1 - 4.9e-05 23.4 2.3 0.00037 20.6 0.4 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) DUF1762 PF08574.5 CBZ29810.1 - 0.00016 21.9 2.4 0.00039 20.7 1.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1762) Tetraspannin PF00335.15 CBZ29812.1 - 2.8e-10 39.8 13.6 4.5e-10 39.1 9.4 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF2733 PF10813.3 CBZ29812.1 - 0.62 9.6 3.3 1.5 8.4 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) Cation_efflux PF01545.16 CBZ29812.1 - 2.5 7.1 5.8 3.9 6.4 4.0 1.2 1 0 0 1 1 1 0 Cation efflux family Claudin_2 PF13903.1 CBZ29812.1 - 5.9 6.5 18.0 0.18 11.4 4.3 2.6 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 CBZ29812.1 - 9.4 6.4 8.2 2.6 8.2 3.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Peptidase_M14 PF00246.19 CBZ29815.1 - 7.9e-22 78.1 0.0 1.4e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF3366 PF11846.3 CBZ29817.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) zf-DHHC PF01529.15 CBZ29818.1 - 7.9e-47 158.8 0.2 1.4e-46 158.0 0.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase A_deamin PF02137.13 CBZ29819.1 - 1.9e-24 86.6 0.0 3.4e-24 85.8 0.0 1.3 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain GST_N_3 PF13417.1 CBZ29820.1 - 1e-26 92.9 0.0 8.7e-18 64.3 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CBZ29820.1 - 5.6e-21 74.3 0.1 1e-12 47.8 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CBZ29820.1 - 2.9e-14 52.6 2.6 4e-06 26.6 0.2 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CBZ29820.1 - 2.2e-12 46.9 1.1 0.00011 22.2 0.0 3.2 4 0 0 4 4 4 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CBZ29820.1 - 5.8e-07 29.4 0.0 0.0075 16.2 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBZ29820.1 - 1.3e-06 28.7 0.0 0.041 14.3 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 CBZ29820.1 - 0.14 12.1 0.6 0.72 9.8 0.1 2.2 2 0 0 2 2 2 0 Glutaredoxin RRM_1 PF00076.17 CBZ29822.1 - 2e-09 36.9 0.0 2.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ29822.1 - 1.5e-06 28.0 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ29822.1 - 0.00081 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBZ29822.1 - 0.00095 18.9 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 RNA binding motif Mpv17_PMP22 PF04117.7 CBZ29823.1 - 6.2e-14 51.3 1.2 1.4e-13 50.2 0.9 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family WD40 PF00400.27 CBZ29824.1 - 8e-27 92.1 12.3 0.00026 20.7 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Sugar_tr PF00083.19 CBZ29825.1 - 2.6e-136 454.8 28.4 3.1e-136 454.5 19.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CBZ29825.1 - 9.4e-13 47.5 25.9 9.4e-13 47.5 18.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Autophagy_N PF03986.8 CBZ29826.1 - 2.2e-27 95.6 0.4 3.6e-27 94.9 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CBZ29826.1 - 1.1e-25 89.5 2.6 2.1e-25 88.6 1.8 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CBZ29826.1 - 3.3e-11 42.0 0.6 6.7e-11 41.1 0.4 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Glyco_tranf_2_3 PF13641.1 CBZ29827.1 - 2.1e-05 24.4 0.1 4.8e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CBZ29827.1 - 0.0051 16.5 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 ABC_tran PF00005.22 CBZ29828.1 - 1.4e-44 151.7 0.1 1.1e-20 74.3 0.0 3.3 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CBZ29828.1 - 3.8e-19 69.7 0.1 0.00018 21.5 0.0 4.3 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 CBZ29828.1 - 3.8e-11 42.6 3.0 0.00031 20.0 0.0 5.1 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBZ29828.1 - 7.6e-08 31.7 0.6 0.0091 15.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CBZ29828.1 - 3.3e-07 29.6 0.1 0.0091 15.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBZ29828.1 - 4.3e-06 27.5 1.8 0.014 16.1 0.0 3.8 4 0 0 4 4 3 1 AAA domain SbcCD_C PF13558.1 CBZ29828.1 - 4.4e-05 23.3 0.3 0.011 15.5 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 CBZ29828.1 - 0.00028 20.4 0.9 2.4 7.5 0.0 3.9 4 0 0 4 4 4 1 AAA-like domain AAA_14 PF13173.1 CBZ29828.1 - 0.00032 20.6 0.2 1 9.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 CBZ29828.1 - 0.0009 19.4 0.2 1 9.5 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CBZ29828.1 - 0.00098 19.2 0.0 0.79 9.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.1 CBZ29828.1 - 0.001 19.2 0.0 2.2 8.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CBZ29828.1 - 0.0012 17.9 0.8 24 3.8 0.0 4.7 5 1 0 5 5 5 0 AAA ATPase domain Miro PF08477.8 CBZ29828.1 - 0.0013 19.2 0.5 2.6 8.5 0.0 3.5 3 0 0 3 3 3 1 Miro-like protein ABC_tran_2 PF12848.2 CBZ29828.1 - 0.0016 18.2 3.7 0.0016 18.2 2.6 4.3 4 1 0 4 4 3 1 ABC transporter AAA_5 PF07728.9 CBZ29828.1 - 0.0024 17.5 0.1 1.3 8.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 CBZ29828.1 - 0.0033 17.3 0.1 0.68 9.9 0.1 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 CBZ29828.1 - 0.0054 16.6 0.1 1.2 9.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CBZ29828.1 - 0.0084 16.1 6.7 1 9.3 0.0 3.2 3 2 1 4 4 4 2 AAA ATPase domain AAA_28 PF13521.1 CBZ29828.1 - 0.018 14.9 5.3 0.26 11.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 CBZ29828.1 - 0.043 13.4 0.1 5.1 6.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 CBZ29828.1 - 0.33 11.2 7.1 1.7 8.9 0.0 3.5 4 0 0 4 4 2 0 AAA domain AAA_23 PF13476.1 CBZ29828.1 - 0.55 10.5 0.0 0.55 10.5 0.0 4.9 4 2 0 5 5 5 0 AAA domain CK1gamma_C PF12605.3 CBZ29828.1 - 0.8 10.3 3.4 13 6.4 0.1 2.5 2 0 0 2 2 2 0 Casein kinase 1 gamma C terminal HSP90 PF00183.13 CBZ29829.1 - 4.1e-262 870.3 34.5 4.8e-262 870.0 23.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CBZ29829.1 - 3.1e-13 49.5 0.6 1.2e-12 47.6 0.1 2.4 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ29829.1 - 7.6e-13 48.1 0.0 1.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.13 CBZ29829.1 - 0.093 13.1 7.0 0.2 12.0 0.7 3.5 3 0 0 3 3 3 0 Ribosomal protein S20 HSP90 PF00183.13 CBZ29830.1 - 4.1e-262 870.3 34.5 4.8e-262 870.0 23.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CBZ29830.1 - 3.1e-13 49.5 0.6 1.2e-12 47.6 0.1 2.4 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ29830.1 - 7.6e-13 48.1 0.0 1.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.13 CBZ29830.1 - 0.093 13.1 7.0 0.2 12.0 0.7 3.5 3 0 0 3 3 3 0 Ribosomal protein S20 HSP90 PF00183.13 CBZ29831.1 - 4.1e-262 870.3 34.5 4.8e-262 870.0 23.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CBZ29831.1 - 3.1e-13 49.5 0.6 1.2e-12 47.6 0.1 2.4 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ29831.1 - 7.6e-13 48.1 0.0 1.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.13 CBZ29831.1 - 0.093 13.1 7.0 0.2 12.0 0.7 3.5 3 0 0 3 3 3 0 Ribosomal protein S20 WD40 PF00400.27 CBZ29832.1 - 1.1e-16 59.9 1.3 3.1e-06 26.8 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Abhydrolase_5 PF12695.2 CBZ29835.1 - 7.4e-20 71.1 0.3 5.2e-19 68.4 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ29835.1 - 8.6e-15 55.2 2.4 1e-11 45.1 1.6 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ29835.1 - 7.9e-08 32.1 0.4 1.2e-06 28.2 0.3 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CBZ29835.1 - 0.00028 20.3 0.3 0.14 11.6 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CBZ29835.1 - 0.011 15.0 0.1 0.089 11.9 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CBZ29835.1 - 0.016 14.7 0.4 0.084 12.4 0.2 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.8 CBZ29835.1 - 0.018 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF531 PF04407.7 CBZ29835.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF531) MutS_V PF00488.16 CBZ29836.1 - 8.7e-82 274.0 0.0 1.5e-81 273.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CBZ29836.1 - 2.7e-28 99.1 0.6 2.7e-28 99.1 0.4 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 CBZ29836.1 - 1.9e-16 59.9 1.3 3.8e-16 59.0 0.9 1.5 1 0 0 1 1 1 1 MutS family domain IV Lipoprotein_7 PF01540.11 CBZ29836.1 - 0.023 13.7 0.8 2.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Adhesin lipoprotein AAA_29 PF13555.1 CBZ29836.1 - 0.024 14.1 0.0 0.32 10.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain IstB_IS21_ATP PF08483.6 CBZ29841.1 - 3.3 7.4 7.7 12 5.6 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding N-terminal FAD_binding_7 PF03441.9 CBZ29842.1 - 4.4e-97 324.6 0.9 6.1e-97 324.1 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 CBZ29842.1 - 2.7e-31 108.5 0.0 5.7e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase DUF4132 PF13569.1 CBZ29842.1 - 0.086 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) SET PF00856.23 CBZ29846.1 - 4.8e-08 33.4 0.0 1.2e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 SET domain ADH_N PF08240.7 CBZ29847.1 - 3.9e-24 84.5 0.7 1.1e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CBZ29847.1 - 3e-17 62.4 0.0 4.7e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CBZ29847.1 - 0.011 16.6 0.0 0.02 15.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase LRR_4 PF12799.2 CBZ29848.1 - 5.8e-21 73.6 0.0 0.0058 16.2 0.0 7.9 4 4 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ29848.1 - 4.4e-15 55.1 8.3 0.031 14.0 0.1 6.7 6 1 0 6 6 6 5 Leucine rich repeat LRR_6 PF13516.1 CBZ29848.1 - 9e-07 28.3 0.3 0.42 10.8 0.0 6.5 6 1 1 7 7 7 2 Leucine Rich repeat LRR_7 PF13504.1 CBZ29848.1 - 0.024 14.7 18.5 7.1 7.3 0.0 9.8 11 1 0 11 11 11 0 Leucine rich repeat LRR_1 PF00560.28 CBZ29848.1 - 0.044 13.8 16.5 4 7.8 0.3 8.9 8 1 0 8 8 8 0 Leucine Rich Repeat NifU PF01106.12 CBZ29850.1 - 5.6e-15 54.8 0.1 1e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 CBZ29850.1 - 4.5e-11 42.2 0.1 8.7e-09 34.8 0.0 2.5 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal DUF2277 PF10041.4 CBZ29850.1 - 4.8 7.2 6.0 27 4.7 0.4 3.6 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2277) RtcB PF01139.12 CBZ29852.1 - 1.2e-91 307.7 0.0 1.4e-91 307.6 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB FYVE PF01363.16 CBZ29853.1 - 0.017 15.0 14.4 0.088 12.7 10.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2 PF00096.21 CBZ29853.1 - 7 7.2 14.7 7.8 7.0 0.1 4.2 3 2 0 3 3 3 0 Zinc finger, C2H2 type Fer4_6 PF12837.2 CBZ29853.1 - 9.7 6.2 16.7 3.3 7.7 2.6 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain SynMuv_product PF06047.6 CBZ29855.1 - 4.3e-14 52.1 1.0 9.9e-14 50.9 0.7 1.5 1 0 0 1 1 1 1 Ras-induced vulval development antagonist BRE1 PF08647.6 CBZ29857.1 - 9.9e-21 73.5 10.5 9.9e-21 73.5 7.3 10.6 3 2 5 9 9 9 3 BRE1 E3 ubiquitin ligase AAA_13 PF13166.1 CBZ29857.1 - 0.0002 19.9 27.1 0.0002 19.9 18.8 6.0 1 1 4 6 6 6 4 AAA domain DUF4094 PF13334.1 CBZ29857.1 - 0.0014 18.9 3.0 0.0014 18.9 2.1 8.0 6 4 2 8 8 8 1 Domain of unknown function (DUF4094) Reo_sigmaC PF04582.7 CBZ29857.1 - 0.0023 17.1 2.2 0.0023 17.1 1.6 7.2 3 2 4 8 8 8 5 Reovirus sigma C capsid protein rve_3 PF13683.1 CBZ29857.1 - 0.22 11.0 1.9 5.3 6.6 0.1 3.8 2 1 1 3 3 3 0 Integrase core domain IGR PF09597.5 CBZ29858.1 - 0.00073 19.3 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 IGR protein motif Apc3 PF12895.2 CBZ29859.1 - 5.2e-05 23.3 0.3 0.19 11.9 0.0 4.1 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.4 CBZ29859.1 - 0.0001 22.2 1.1 0.39 10.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ29859.1 - 0.0002 20.9 0.6 7.8 6.5 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR_2 PF13041.1 CBZ29859.1 - 0.072 13.0 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 PPR repeat family TPR_2 PF07719.12 CBZ29859.1 - 0.1 12.5 0.0 26 5.0 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat IFT57 PF10498.4 CBZ29861.1 - 3.6e-71 239.8 7.7 4e-71 239.6 5.4 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 AAA_13 PF13166.1 CBZ29861.1 - 0.00083 17.9 5.0 0.00088 17.8 3.5 1.1 1 0 0 1 1 1 1 AAA domain Peptidase_M75 PF09375.5 CBZ29861.1 - 0.0014 18.0 1.4 0.0023 17.2 1.0 1.3 1 0 0 1 1 1 1 Imelysin V_ATPase_I PF01496.14 CBZ29861.1 - 0.0089 13.9 5.9 0.011 13.6 4.1 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Spc7 PF08317.6 CBZ29861.1 - 0.015 14.0 7.7 0.022 13.4 5.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein mRNA_stabil PF13929.1 CBZ29861.1 - 0.015 14.2 0.2 0.059 12.3 0.0 1.7 1 1 0 2 2 2 0 mRNA stabilisation DUF1664 PF07889.7 CBZ29861.1 - 0.019 14.7 9.8 0.059 13.1 2.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 CBZ29861.1 - 0.023 13.8 3.9 0.035 13.2 2.2 1.4 1 1 0 1 1 1 0 Reovirus sigma C capsid protein Apolipoprotein PF01442.13 CBZ29861.1 - 0.044 13.2 11.3 0.065 12.7 7.3 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Laminin_II PF06009.7 CBZ29861.1 - 0.051 13.3 9.9 1 9.1 0.2 2.4 1 1 1 2 2 2 0 Laminin Domain II MutS_III PF05192.13 CBZ29861.1 - 0.061 13.1 3.2 0.094 12.4 2.2 1.3 1 0 0 1 1 1 0 MutS domain III TPR_MLP1_2 PF07926.7 CBZ29861.1 - 0.062 13.0 11.1 0.13 11.9 7.5 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CHDCT2 PF08074.6 CBZ29861.1 - 0.062 13.0 2.3 0.21 11.2 0.7 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain AKNA PF12443.3 CBZ29861.1 - 0.094 12.7 8.0 1.4 9.0 0.7 2.8 2 1 1 3 3 3 0 AT-hook-containing transcription factor IncA PF04156.9 CBZ29861.1 - 0.1 12.2 12.2 0.21 11.1 8.0 1.8 2 1 1 3 3 3 0 IncA protein DUF745 PF05335.8 CBZ29861.1 - 0.12 11.8 9.5 0.7 9.3 4.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Syntaxin_2 PF14523.1 CBZ29861.1 - 0.25 11.3 7.1 0.52 10.3 3.7 2.2 1 1 1 2 2 2 0 Syntaxin-like protein Sec8_exocyst PF04048.9 CBZ29861.1 - 0.26 10.9 6.8 0.46 10.1 3.5 2.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Atg14 PF10186.4 CBZ29861.1 - 0.29 10.0 11.8 1.6 7.5 1.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 WXG100 PF06013.7 CBZ29861.1 - 0.41 10.6 8.6 5.8 6.9 4.9 2.9 2 1 0 2 2 2 0 Proteins of 100 residues with WXG FUSC PF04632.7 CBZ29861.1 - 0.47 8.8 2.0 0.61 8.4 1.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PilJ PF13675.1 CBZ29861.1 - 0.49 10.7 8.5 0.64 10.3 0.6 2.9 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Fzo_mitofusin PF04799.8 CBZ29861.1 - 0.53 9.6 7.7 0.68 9.2 4.7 1.6 1 1 0 1 1 1 0 fzo-like conserved region Mnd1 PF03962.10 CBZ29861.1 - 1.3 8.6 10.1 2.8 7.5 7.0 1.7 1 1 0 1 1 1 0 Mnd1 family DUF948 PF06103.6 CBZ29861.1 - 1.7 8.5 7.2 9.3 6.1 2.3 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4200 PF13863.1 CBZ29861.1 - 2.9 7.8 12.2 1.2 9.0 2.4 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) OmpH PF03938.9 CBZ29861.1 - 3.8 7.4 14.1 8.3 6.3 9.7 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF883 PF05957.8 CBZ29861.1 - 4.1 7.8 8.1 5.7 7.4 0.6 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) EF-hand_7 PF13499.1 CBZ29863.1 - 1.3e-06 28.4 0.1 2.6e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ29863.1 - 0.0001 21.8 0.0 0.00048 19.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBZ29863.1 - 0.00083 18.4 0.0 0.0026 16.9 0.0 1.9 1 0 0 1 1 1 1 EF hand Membralin PF09746.4 CBZ29864.1 - 2.2 7.2 3.8 4.6 6.1 2.6 1.5 1 0 0 1 1 1 0 Tumour-associated protein He_PIG_assoc PF10632.4 CBZ29866.1 - 0.02 14.2 0.0 0.09 12.1 0.0 2.1 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase WD40 PF00400.27 CBZ29866.1 - 0.021 14.6 0.7 16 5.5 0.1 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat ERG4_ERG24 PF01222.12 CBZ29867.1 - 3.3e-103 345.5 25.9 4.1e-103 345.2 17.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3984 PF13136.1 CBZ29867.1 - 0.59 9.3 5.8 0.84 8.8 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Corona_nucleoca PF00937.13 CBZ29867.1 - 0.62 8.9 7.8 0.89 8.4 5.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1509 PF07420.6 CBZ29867.1 - 8.7 5.5 9.5 13 4.9 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) TPR_11 PF13414.1 CBZ29869.1 - 0.0003 20.3 2.2 0.0003 20.3 1.5 2.8 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBZ29869.1 - 0.015 15.1 9.3 0.13 12.2 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ29869.1 - 0.025 14.6 5.2 0.056 13.5 3.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBZ29869.1 - 0.035 14.4 0.2 0.1 12.9 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ29869.1 - 0.074 12.7 8.2 0.67 9.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SKI PF01202.17 CBZ29869.1 - 0.54 10.1 2.6 0.8 9.5 0.1 2.3 3 0 0 3 3 3 0 Shikimate kinase PTR2 PF00854.16 CBZ29870.1 - 6e-17 61.4 10.8 8.5e-16 57.6 0.0 3.4 3 1 0 3 3 3 2 POT family MFS_1 PF07690.11 CBZ29870.1 - 3e-09 36.0 29.4 1.2e-08 34.1 6.2 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L6e PF01159.14 CBZ29871.1 - 7.5e-34 116.2 0.8 4e-33 113.8 0.6 2.0 1 1 0 1 1 1 1 Ribosomal protein L6e KOW PF00467.24 CBZ29871.1 - 0.0011 18.6 0.0 0.0038 16.8 0.0 1.9 1 1 1 2 2 2 1 KOW motif WD40 PF00400.27 CBZ29872.1 - 4.3e-16 58.0 6.8 6.3e-06 25.8 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat bact-PGI_C PF10432.4 CBZ29873.1 - 0.0052 16.4 0.3 0.0093 15.6 0.2 1.3 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal region Vitelline_membr PF10542.4 CBZ29873.1 - 0.038 13.6 0.5 0.14 11.8 0.4 2.0 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region TCRP1 PF14944.1 CBZ29874.1 - 0.024 14.5 1.2 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 Tongue Cancer Chemotherapy Resistant Protein 1 AMNp_N PF10423.4 CBZ29874.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus DUF2040 PF09745.4 CBZ29875.1 - 0.00085 19.1 0.2 0.0021 17.8 0.1 1.6 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) Cyclin PF08613.6 CBZ29877.1 - 7.2e-28 97.8 0.0 2.9e-27 95.9 0.0 2.1 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CBZ29877.1 - 3.2e-05 23.5 0.0 5.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain NIF PF03031.13 CBZ29878.1 - 1.3e-19 70.3 0.2 3.3e-17 62.5 0.0 2.8 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase Tubulin PF00091.20 CBZ29880.1 - 2.8e-70 236.5 0.0 4.5e-70 235.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ29880.1 - 6.5e-48 161.9 0.1 9.7e-48 161.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBZ29880.1 - 5.8e-05 23.1 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBZ29880.1 - 0.0078 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 CBZ29881.1 - 3.7e-70 236.1 0.0 5.8e-70 235.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ29881.1 - 7.7e-48 161.6 0.1 1.2e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CBZ29881.1 - 7.1e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 CBZ29881.1 - 0.0095 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Oxidored_FMN PF00724.15 CBZ29882.1 - 2.1e-70 237.4 0.0 3e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.9 CBZ29882.1 - 1.6e-14 54.2 0.1 2.7e-10 40.4 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CBZ29882.1 - 3.8e-10 40.0 0.1 0.00045 20.5 0.1 3.7 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CBZ29882.1 - 1.2e-09 38.5 0.3 0.0054 16.8 0.0 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ29882.1 - 9.7e-09 35.1 0.1 6.2e-08 32.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CBZ29882.1 - 2.6e-07 29.4 1.9 2.4e-06 26.3 0.1 2.8 4 0 0 4 4 4 1 HI0933-like protein K_oxygenase PF13434.1 CBZ29882.1 - 7.6e-07 28.3 0.3 0.011 14.6 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 CBZ29882.1 - 5.9e-06 25.4 3.8 9.9e-06 24.6 0.1 3.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.17 CBZ29882.1 - 7.5e-05 21.7 0.8 0.00024 20.0 0.4 2.0 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 CBZ29882.1 - 7.5e-05 22.5 0.0 0.017 14.8 0.0 2.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 CBZ29882.1 - 9.3e-05 21.6 0.3 0.00015 20.9 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CBZ29882.1 - 0.00011 21.9 1.3 0.043 13.5 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 CBZ29882.1 - 0.00015 21.4 0.3 0.091 12.4 0.0 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CBZ29882.1 - 0.00018 20.4 2.8 0.00024 20.1 0.1 2.4 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 CBZ29882.1 - 0.0003 20.9 0.1 0.027 14.7 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FMO-like PF00743.14 CBZ29882.1 - 0.0021 16.3 0.2 3.1 5.8 0.0 3.0 2 1 0 3 3 3 1 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 CBZ29882.1 - 0.0087 15.1 0.7 0.079 11.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 CBZ29882.1 - 0.0092 15.0 0.2 0.022 13.8 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 CBZ29882.1 - 0.013 14.5 0.2 0.73 8.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase UDPG_MGDP_dh_N PF03721.9 CBZ29882.1 - 0.026 13.9 0.0 0.25 10.6 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 CBZ29882.1 - 0.027 14.3 0.0 4.4 7.1 0.0 3.0 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 CBZ29882.1 - 0.043 13.8 0.0 19 5.2 0.0 3.2 3 0 0 3 3 3 0 TrkA-N domain B12-binding PF02310.14 CBZ29882.1 - 0.057 13.2 0.5 0.92 9.3 0.0 2.9 3 0 0 3 3 2 0 B12 binding domain Lycopene_cycl PF05834.7 CBZ29882.1 - 0.14 11.0 0.1 0.45 9.3 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 CBZ29882.1 - 0.78 9.5 3.4 4 7.2 0.0 3.2 4 0 0 4 4 3 0 ThiF family DUF3392 PF11872.3 CBZ29887.1 - 0.038 13.9 0.3 0.087 12.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) zf-Tim10_DDP PF02953.10 CBZ29888.1 - 0.0072 15.5 3.0 0.26 10.6 2.1 2.4 1 1 0 1 1 1 1 Tim10/DDP family zinc finger DUF3874 PF12990.2 CBZ29888.1 - 0.056 13.5 0.2 0.16 12.1 0.1 1.8 1 1 1 2 2 2 0 Domain of unknonw function from B. Theta Gene description (DUF3874) DnaJ PF00226.26 CBZ29889.1 - 1.5e-21 75.8 0.4 2.3e-21 75.2 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Ribosomal_S3_C PF00189.15 CBZ29891.1 - 9.8e-16 57.7 1.0 9.8e-16 57.7 0.7 1.7 2 1 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CBZ29891.1 - 6.2e-09 35.2 0.2 1.5e-08 34.0 0.1 1.6 2 0 0 2 2 2 1 KH domain FIBP PF05427.6 CBZ29894.1 - 9.1e-06 25.1 0.1 0.022 14.0 0.0 2.5 3 0 0 3 3 3 2 Acidic fibroblast growth factor binding (FIBP) WD40 PF00400.27 CBZ29895.1 - 5.3e-08 32.4 6.2 0.0033 17.2 0.2 6.3 6 1 0 6 6 6 2 WD domain, G-beta repeat PQQ_3 PF13570.1 CBZ29895.1 - 0.04 14.2 4.9 24 5.3 0.0 5.7 5 0 0 5 5 5 0 PQQ-like domain NAPRTase PF04095.11 CBZ29896.1 - 1e-65 221.4 0.0 1.3e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family SAM_2 PF07647.12 CBZ29896.1 - 0.071 12.9 0.0 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) SR-25 PF10500.4 CBZ29897.1 - 0.17 11.3 21.6 0.38 10.1 14.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Skp1 PF01466.14 CBZ29898.1 - 5.4e-17 61.5 0.3 7.6e-17 61.1 0.2 1.2 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Rhodanese PF00581.15 CBZ29899.1 - 5.1e-09 36.4 0.0 7.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain DAGAT PF03982.8 CBZ29900.1 - 2.4e-18 65.8 0.0 3.3e-11 42.4 0.0 4.1 4 0 0 4 4 4 3 Diacylglycerol acyltransferase E1-E2_ATPase PF00122.15 CBZ29901.1 - 5.4e-48 163.0 0.9 5.4e-48 163.0 0.6 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBZ29901.1 - 2.3e-39 134.7 5.5 2.3e-39 134.7 3.8 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBZ29901.1 - 1.2e-15 58.5 0.2 0.0001 22.7 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ29901.1 - 2.3e-09 37.6 0.0 6.5e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBZ29901.1 - 6.7e-07 28.6 0.0 1.6e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CBZ29901.1 - 3.9e-06 26.7 0.0 9.5e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBZ29901.1 - 8e-05 22.3 0.3 0.00014 21.5 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PSP1 PF04468.7 CBZ29902.1 - 9.4e-10 38.3 0.4 2.5e-09 37.0 0.2 1.8 1 1 0 1 1 1 1 PSP1 C-terminal conserved region PPTA PF01239.17 CBZ29903.1 - 2.3e-28 96.3 11.2 3.2e-08 32.5 0.2 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_MLP1_2 PF07926.7 CBZ29905.1 - 0.0072 16.0 2.1 0.021 14.5 1.4 1.8 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Med3 PF11593.3 CBZ29905.1 - 0.023 13.9 2.0 0.036 13.3 1.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MGC-24 PF05283.6 CBZ29905.1 - 0.4 10.4 5.5 0.66 9.7 3.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Abhydrolase_5 PF12695.2 CBZ29906.1 - 0.00013 21.7 0.0 0.00069 19.3 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ29906.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Voltage_CLC PF00654.15 CBZ29907.1 - 1.5e-94 316.9 27.7 2.1e-93 313.1 16.9 2.2 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 CBZ29907.1 - 3e-14 52.5 3.4 1.5e-08 34.2 0.1 2.8 3 0 0 3 3 3 2 CBS domain YEATS PF03366.11 CBZ29909.1 - 1.8e-09 37.2 0.0 3.2e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 YEATS family Guanylate_kin PF00625.16 CBZ29910.1 - 1.9e-49 167.5 0.0 2.4e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 CBZ29910.1 - 9.7e-08 32.3 0.2 2.1e-07 31.2 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ29910.1 - 1.3e-06 28.3 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ29910.1 - 2.7e-05 24.9 0.1 6.9e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 CBZ29910.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CBZ29910.1 - 0.00019 21.5 0.1 0.0023 18.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CBZ29910.1 - 0.00067 18.8 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CBZ29910.1 - 0.0033 17.4 0.1 0.008 16.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 CBZ29910.1 - 0.012 16.1 0.0 0.02 15.3 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein ADK PF00406.17 CBZ29910.1 - 0.017 14.9 0.3 0.83 9.5 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase AAA_5 PF07728.9 CBZ29910.1 - 0.033 13.9 0.0 0.12 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.9 CBZ29910.1 - 0.044 13.4 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CBZ29910.1 - 0.054 13.4 0.1 0.29 11.0 0.0 2.0 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CBZ29910.1 - 0.068 13.4 0.1 0.15 12.3 0.1 1.9 1 1 0 1 1 1 0 ABC transporter Cytidylate_kin2 PF13189.1 CBZ29910.1 - 0.092 12.6 0.4 0.18 11.6 0.1 1.6 2 1 0 2 2 2 0 Cytidylate kinase-like family zf-CW PF07496.10 CBZ29911.1 - 8.7e-17 60.5 15.1 1.1e-12 47.4 5.3 3.6 3 0 0 3 3 3 2 CW-type Zinc Finger Yippee-Mis18 PF03226.9 CBZ29912.1 - 0.00056 19.9 3.7 0.42 10.6 0.1 3.2 3 0 0 3 3 3 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SlyX PF04102.7 CBZ29912.1 - 4.9 7.5 15.1 0.75 10.2 0.8 3.4 1 1 1 2 2 2 0 SlyX TIG PF01833.19 CBZ29915.1 - 0.0029 17.5 3.0 0.15 12.0 0.1 3.4 3 0 0 3 3 3 1 IPT/TIG domain NPCBM_assoc PF10633.4 CBZ29915.1 - 0.0074 16.3 2.0 2.2 8.3 0.1 2.7 2 0 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase RS4NT PF08071.7 CBZ29915.1 - 0.2 11.5 0.1 0.34 10.8 0.1 1.3 1 0 0 1 1 1 0 RS4NT (NUC023) domain RhodobacterPufX PF11511.3 CBZ29915.1 - 2.2 7.7 4.9 6.9 6.1 3.4 1.8 1 0 0 1 1 1 0 Intrinsic membrane protein PufX PUF PF00806.14 CBZ29916.1 - 8.1e-50 163.5 5.3 4.5e-06 25.8 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ax_dynein_light PF10211.4 CBZ29919.1 - 3.3e-45 154.2 12.5 4.2e-45 153.9 8.6 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain SecM PF06558.7 CBZ29919.1 - 0.12 12.0 0.7 0.55 9.8 0.3 2.0 2 0 0 2 2 2 0 Secretion monitor precursor protein (SecM) Adeno_E4 PF05385.6 CBZ29919.1 - 0.3 11.0 2.2 1.3 8.9 1.2 2.0 2 0 0 2 2 2 0 Mastadenovirus early E4 13 kDa protein DUF972 PF06156.8 CBZ29919.1 - 8.4 6.7 11.6 6.8 7.0 6.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AAA PF00004.24 CBZ29921.1 - 8.5e-14 51.8 0.1 2.4e-09 37.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CBZ29921.1 - 1.3e-05 24.9 0.0 5.6e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ29921.1 - 1.5e-05 25.8 0.2 4.3e-05 24.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CBZ29921.1 - 6.3e-05 23.0 3.3 0.00022 21.2 0.0 3.2 2 2 2 4 4 4 1 AAA ATPase domain AAA_19 PF13245.1 CBZ29921.1 - 6.3e-05 22.6 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CBZ29921.1 - 0.00073 19.4 0.0 0.002 17.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ29921.1 - 0.00076 19.6 0.0 0.0038 17.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CBZ29921.1 - 0.006 15.9 0.0 0.021 14.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CBZ29921.1 - 0.0097 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CBZ29921.1 - 0.011 14.8 0.0 0.028 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 CBZ29921.1 - 0.011 15.3 0.2 0.059 12.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 CBZ29921.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CBZ29921.1 - 0.027 14.8 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CBZ29921.1 - 0.041 13.8 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CBZ29921.1 - 0.052 12.6 0.0 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.16 CBZ29921.1 - 0.057 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CBZ29921.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CBZ29921.1 - 0.067 13.3 0.1 0.57 10.3 0.0 2.5 3 0 0 3 3 2 0 RNA helicase PhoH PF02562.11 CBZ29921.1 - 0.083 12.1 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 CBZ29921.1 - 0.098 12.5 0.0 0.35 10.7 0.0 2.1 2 1 0 2 2 1 0 AAA domain NACHT PF05729.7 CBZ29921.1 - 0.099 12.2 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.1 CBZ29921.1 - 0.11 12.1 2.7 0.12 11.9 0.2 2.2 2 1 0 2 2 2 0 AAA domain PPR_2 PF13041.1 CBZ29922.1 - 0.00012 22.0 0.3 0.00088 19.2 0.1 2.4 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.15 CBZ29922.1 - 0.00075 19.3 0.1 2 8.5 0.0 3.6 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.1 CBZ29922.1 - 0.0045 17.1 0.2 0.062 13.6 0.0 3.0 3 0 0 3 3 3 1 Pentatricopeptide repeat domain TPR_19 PF14559.1 CBZ29922.1 - 0.014 15.6 0.1 0.1 12.9 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3613 PF12266.3 CBZ29922.1 - 0.08 12.4 1.1 0.23 11.0 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) F-box PF00646.28 CBZ29923.1 - 0.014 15.0 0.9 0.036 13.7 0.6 1.6 1 0 0 1 1 1 0 F-box domain GcrA PF07750.6 CBZ29923.1 - 0.17 12.1 2.2 0.17 12.0 0.2 1.9 2 0 0 2 2 2 0 GcrA cell cycle regulator TFIIA PF03153.8 CBZ29923.1 - 4 7.2 5.9 6.4 6.5 4.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 CBZ29924.1 - 3.2e-13 49.0 4.8 3.1e-07 29.9 0.0 5.0 5 1 0 5 5 5 2 WD domain, G-beta repeat SlyX PF04102.7 CBZ29924.1 - 0.079 13.3 0.6 2.2 8.6 0.1 2.6 2 0 0 2 2 2 0 SlyX CNH PF00780.17 CBZ29924.1 - 0.14 11.5 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 CNH domain PQQ_3 PF13570.1 CBZ29924.1 - 0.48 10.7 7.3 0.9 9.9 0.0 4.1 3 1 1 4 4 4 0 PQQ-like domain WD40 PF00400.27 CBZ29925.1 - 1.9e-12 46.5 11.5 8.7e-05 22.2 0.2 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Atg14 PF10186.4 CBZ29925.1 - 0.022 13.6 2.5 0.041 12.8 1.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GAS2 PF02187.12 CBZ29927.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain ARL6IP6 PF15062.1 CBZ29928.1 - 5.1 7.0 7.4 21 5.1 0.3 3.1 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Thioredoxin PF00085.15 CBZ29930.1 - 9.7e-10 38.0 0.2 1.5e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBZ29930.1 - 0.0025 17.8 0.6 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like YfmQ PF10787.4 CBZ29930.1 - 0.0059 15.9 0.2 0.0084 15.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein from bacillus cereus group Thioredoxin_2 PF13098.1 CBZ29930.1 - 0.014 15.5 1.1 0.036 14.2 0.8 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.16 CBZ29930.1 - 0.029 14.0 0.1 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.1 CBZ29930.1 - 0.03 14.3 0.1 0.084 12.9 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like Ribosomal_L29 PF00831.18 CBZ29930.1 - 0.16 11.7 2.2 10 5.8 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein MFS_1 PF07690.11 CBZ29931.1 - 1.7e-16 59.9 47.6 9.4e-10 37.7 17.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 CBZ29931.1 - 8.3e-07 28.1 26.2 1.8e-06 27.0 18.2 1.5 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.14 CBZ29931.1 - 3.7e-06 25.7 20.2 0.00021 19.9 14.0 2.2 1 1 0 1 1 1 1 LacY proton/sugar symporter MFS_1_like PF12832.2 CBZ29931.1 - 0.00031 20.4 0.1 0.0017 18.1 0.1 2.3 1 0 0 1 1 1 1 MFS_1 like family ABC1 PF03109.11 CBZ29932.1 - 2.1e-29 101.9 0.0 4.1e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 CBZ29932.1 - 0.0019 18.0 1.0 0.0059 16.3 0.1 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ29932.1 - 0.017 14.4 0.0 0.051 12.9 0.0 1.8 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 CBZ29932.1 - 0.039 13.1 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.20 CBZ29932.1 - 0.052 12.6 0.0 0.092 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain HrpB7 PF09486.5 CBZ29932.1 - 0.18 11.7 6.6 0.064 13.1 1.6 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Cwf_Cwc_15 PF04889.7 CBZ29933.1 - 3.2e-06 27.0 5.8 1.1e-05 25.3 3.9 1.8 1 1 1 2 2 2 1 Cwf15/Cwc15 cell cycle control protein Chibby PF14645.1 CBZ29933.1 - 0.012 15.5 1.9 0.75 9.6 0.0 2.2 1 1 0 2 2 2 0 Chibby family HrpA_pilin PF09589.5 CBZ29933.1 - 0.051 14.0 10.0 4.8 7.6 0.0 2.2 1 1 1 2 2 2 0 HrpA pilus formation protein TFIIF_alpha PF05793.7 CBZ29933.1 - 0.059 11.7 11.3 0.063 11.6 7.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.8 CBZ29933.1 - 0.06 11.1 1.2 0.068 10.9 0.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.8 CBZ29933.1 - 0.065 12.8 3.8 0.12 11.9 2.6 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 CBZ29933.1 - 0.98 7.1 11.7 1.4 6.7 8.1 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 CBZ29933.1 - 1.4 6.8 7.3 1.4 6.8 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 CBZ29933.1 - 3.6 7.4 7.0 3.5 7.4 4.3 1.3 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 PBP1_TM PF14812.1 CBZ29933.1 - 5.4 7.3 10.5 0.87 9.9 3.2 2.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Baculo_19 PF04798.7 CBZ29934.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region DUF1982 PF09326.6 CBZ29935.1 - 0.045 13.9 0.0 0.28 11.3 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1982) DUF3656 PF12392.3 CBZ29935.1 - 0.08 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Collagenase Aminotran_1_2 PF00155.16 CBZ29936.1 - 2e-52 178.3 0.1 2.2e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CBZ29936.1 - 2.4e-06 26.0 0.2 3.6e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CBZ29936.1 - 4.9e-06 25.5 0.4 1.1e-05 24.4 0.3 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CBZ29936.1 - 2.6e-05 23.4 0.1 3.8e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CBZ29936.1 - 0.00011 21.5 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase RNase_Zc3h12a PF11977.3 CBZ29936.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.6 1 1 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain SNARE PF05739.14 CBZ29937.1 - 4.6e-17 61.4 3.0 4.6e-17 61.4 2.1 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 CBZ29937.1 - 6.3e-06 26.2 1.6 6.3e-06 26.2 1.1 2.3 2 0 0 2 2 2 1 Syntaxin Ubiquitin_3 PF14836.1 CBZ29937.1 - 0.013 15.1 0.4 0.038 13.6 0.2 1.8 1 1 1 2 2 2 0 Ubiquitin-like domain Syntaxin_2 PF14523.1 CBZ29937.1 - 0.063 13.3 8.5 0.17 11.9 2.0 2.5 2 0 0 2 2 2 0 Syntaxin-like protein SPX PF03105.14 CBZ29937.1 - 1.5 8.5 6.4 2.4 7.8 4.5 1.4 1 0 0 1 1 1 0 SPX domain UPF0113 PF03657.8 CBZ29938.1 - 0.0039 16.8 0.0 0.012 15.3 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) Complex1_LYR_1 PF13232.1 CBZ29939.1 - 6.3e-08 32.7 2.5 1e-07 32.0 1.7 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CBZ29939.1 - 3.5e-06 26.6 2.1 5.2e-06 26.1 1.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HopJ PF08888.6 CBZ29939.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.6 1 1 0 1 1 1 0 HopJ type III effector protein DUF1416 PF07210.7 CBZ29939.1 - 0.043 13.4 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Acyl_transf_1 PF00698.16 CBZ29939.1 - 0.059 12.7 0.3 0.062 12.6 0.2 1.0 1 0 0 1 1 1 0 Acyl transferase domain DUF2217 PF10265.4 CBZ29941.1 - 7.4 5.2 6.8 13 4.3 4.7 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Pkinase PF00069.20 CBZ29942.1 - 1.3e-65 221.1 0.0 2.1e-65 220.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29942.1 - 3.7e-31 108.1 0.0 6e-31 107.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CBZ29942.1 - 2.5e-05 23.4 0.2 4.5e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CBZ29942.1 - 6.6e-05 22.0 0.0 0.00025 20.1 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 CBZ29942.1 - 0.044 12.6 0.0 0.073 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DuffyBP_N PF12377.3 CBZ29942.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Duffy binding protein N terminal APH PF01636.18 CBZ29942.1 - 0.14 11.8 0.8 0.38 10.4 0.1 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family MRP-L28 PF09812.4 CBZ29943.1 - 0.00024 20.9 0.2 0.0004 20.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Hist_deacetyl PF00850.14 CBZ29943.1 - 0.053 12.8 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain Imm31 PF15595.1 CBZ29943.1 - 0.15 11.8 0.8 1.5 8.5 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 31 Pkinase PF00069.20 CBZ29944.1 - 4.7e-49 166.8 0.0 1.8e-27 96.1 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29944.1 - 6.2e-30 104.1 0.2 9.5e-21 74.0 0.0 3.2 3 0 0 3 3 3 2 Protein tyrosine kinase FHA PF00498.21 CBZ29944.1 - 5.8e-10 39.1 0.1 0.00085 19.3 0.0 2.7 2 0 0 2 2 2 2 FHA domain Kinase-like PF14531.1 CBZ29944.1 - 3.7e-07 29.3 0.2 4.8e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 CBZ29944.1 - 0.00042 19.7 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family WD40 PF00400.27 CBZ29945.1 - 4.3e-18 64.4 23.5 2.8e-05 23.8 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 CBZ29945.1 - 0.00013 20.2 7.1 0.057 11.5 0.2 3.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 CENP-F_leu_zip PF10473.4 CBZ29945.1 - 0.029 14.2 0.7 0.029 14.2 0.5 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nucleoporin_N PF08801.6 CBZ29945.1 - 0.054 12.2 0.2 0.25 10.0 0.1 1.9 1 1 0 1 1 1 0 Nup133 N terminal like GCK PF07802.6 CBZ29945.1 - 0.11 12.6 0.2 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 GCK domain TMCO5 PF14992.1 CBZ29945.1 - 0.11 11.5 21.1 0.16 11.0 14.6 1.1 1 0 0 1 1 1 0 TMCO5 family BLOC1_2 PF10046.4 CBZ29945.1 - 0.36 10.9 7.4 0.064 13.4 0.6 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.6 CBZ29945.1 - 0.54 10.0 29.5 0.79 9.5 17.8 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 CBZ29945.1 - 0.6 10.4 21.5 1.4 9.3 3.0 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF972) FUSC PF04632.7 CBZ29945.1 - 0.67 8.3 16.1 1 7.7 11.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.2 CBZ29945.1 - 0.82 9.5 28.6 0.018 14.9 9.0 2.3 1 1 1 2 2 2 0 Tropomyosin like Striatin PF08232.7 CBZ29945.1 - 0.86 9.9 16.1 0.93 9.8 0.1 2.5 2 0 0 2 2 2 0 Striatin family OmpH PF03938.9 CBZ29945.1 - 1.2 9.0 27.2 0.065 13.1 6.6 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.1 CBZ29945.1 - 1.7 7.0 13.7 2.4 6.5 9.5 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 CBZ29945.1 - 2.2 5.4 23.6 3.7 4.7 16.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.1 CBZ29945.1 - 2.9 7.0 28.1 1.1 8.4 4.3 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PspB PF06667.7 CBZ29945.1 - 3.2 7.7 7.8 2.8 7.9 0.1 2.9 2 1 1 3 3 3 0 Phage shock protein B G-gamma PF00631.17 CBZ29945.1 - 3.3 7.5 5.9 8.3 6.2 0.0 3.2 2 1 1 3 3 3 0 GGL domain Phage_GP20 PF06810.6 CBZ29945.1 - 3.4 7.1 15.9 0.097 12.1 1.3 2.8 1 1 2 3 3 3 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.3 CBZ29945.1 - 6.3 6.5 28.4 0.098 12.3 4.6 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Aa_trans PF01490.13 CBZ29946.1 - 1.6e-49 168.5 18.7 2e-49 168.1 12.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ29946.1 - 4.5e-11 42.2 19.2 1.6e-09 37.0 9.1 2.8 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family RRM_1 PF00076.17 CBZ29948.1 - 2.2e-08 33.5 0.0 5e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ29948.1 - 0.00068 19.5 0.0 0.0071 16.3 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ29948.1 - 0.047 13.5 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ29949.1 - 2.3e-13 49.5 0.0 1.5e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ29949.1 - 3.1e-09 36.6 0.1 4e-08 33.1 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ29949.1 - 1.3e-05 24.9 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ29950.1 - 2e-10 40.4 0.1 2e-09 37.2 0.0 2.4 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ29950.1 - 3.8e-10 39.2 0.0 1.2e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ29950.1 - 1.8e-08 34.0 0.0 4.7e-08 32.7 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CBZ29951.1 - 1.4e-16 59.8 0.1 2.2e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ29951.1 - 1.5e-11 44.1 0.1 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ29951.1 - 0.007 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_7 PF13176.1 CBZ29952.1 - 0.00036 20.1 1.8 6.9 6.7 0.0 4.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ29952.1 - 0.00055 19.4 12.9 0.33 10.6 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ29952.1 - 0.0022 17.8 21.8 0.011 15.6 1.7 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ29952.1 - 0.018 14.7 26.5 2.2 7.9 1.6 6.2 6 0 0 6 6 6 0 TPR repeat TPR_2 PF07719.12 CBZ29952.1 - 0.02 14.8 17.3 7 6.8 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat GlnD_UR_UTase PF08335.6 CBZ29952.1 - 0.28 10.9 5.7 0.038 13.8 0.2 2.3 2 0 0 2 2 2 0 GlnD PII-uridylyltransferase ubiquitin PF00240.18 CBZ29953.1 - 0.0028 16.9 0.4 3.1 7.2 0.0 2.9 3 1 0 3 3 3 2 Ubiquitin family C2 PF00168.25 CBZ29953.1 - 0.044 13.6 0.3 0.22 11.3 0.0 2.2 2 0 0 2 2 2 0 C2 domain PRA1 PF03208.14 CBZ29955.1 - 2.4e-22 78.9 0.8 4.2e-22 78.1 0.6 1.3 1 0 0 1 1 1 1 PRA1 family protein UbiA PF01040.13 CBZ29955.1 - 0.002 17.4 2.0 0.0026 17.0 1.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family 7tm_1 PF00001.16 CBZ29955.1 - 0.083 12.0 3.7 0.4 9.7 2.6 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) PRA1 PF03208.14 CBZ29956.1 - 1.5e-28 99.0 9.0 2e-28 98.7 6.3 1.1 1 0 0 1 1 1 1 PRA1 family protein zf-DHHC PF01529.15 CBZ29956.1 - 3 7.2 6.0 5 6.4 4.1 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase GST_C PF00043.20 CBZ29957.1 - 5.5e-14 51.9 0.0 1e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CBZ29957.1 - 6.7e-09 35.8 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CBZ29957.1 - 6.8e-08 32.2 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CBZ29957.1 - 6e-07 29.8 0.0 2.1e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CBZ29957.1 - 0.0022 18.1 0.0 0.005 17.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain TauE PF01925.14 CBZ29959.1 - 5.8e-14 52.1 17.4 9e-08 31.8 5.3 2.3 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF3611 PF12263.3 CBZ29959.1 - 0.0031 16.9 2.3 0.12 11.7 0.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3611) DUF3278 PF11683.3 CBZ29959.1 - 0.0061 16.5 2.0 1.2 9.1 0.6 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3278) DUF2681 PF10883.3 CBZ29959.1 - 0.0091 16.1 0.6 0.082 13.1 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2681) DivIC PF04977.10 CBZ29959.1 - 0.041 13.3 0.1 0.098 12.1 0.1 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4131 PF13567.1 CBZ29959.1 - 0.068 12.5 0.4 1.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RseC_MucC PF04246.7 CBZ29959.1 - 1.5 8.4 11.5 1.4 8.4 0.2 3.1 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC DUF202 PF02656.10 CBZ29959.1 - 9.7 6.4 8.4 1.3 9.2 0.3 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Ribul_P_3_epim PF00834.14 CBZ29960.1 - 1.1e-60 204.1 0.1 1.4e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 CBZ29960.1 - 0.00039 19.8 0.1 0.007 15.7 0.1 2.2 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.12 CBZ29960.1 - 0.091 11.9 0.2 0.28 10.3 0.1 1.7 1 1 1 2 2 2 0 PcrB family adh_short PF00106.20 CBZ29963.1 - 1.2e-21 77.3 0.0 1.8e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBZ29963.1 - 1.1e-10 41.7 0.0 1.6e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBZ29963.1 - 8.8e-09 35.2 0.0 1.2e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBZ29963.1 - 0.001 19.1 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBZ29963.1 - 0.0032 17.2 0.0 0.0065 16.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 CBZ29963.1 - 0.039 13.6 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 CBZ29963.1 - 0.04 13.3 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CBZ29963.1 - 0.065 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_M20 PF01546.23 CBZ29965.1 - 3.5e-20 72.2 0.0 5.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CBZ29965.1 - 3.8e-12 45.9 0.0 6.1e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain HEAT PF02985.17 CBZ29966.1 - 6.3e-12 44.5 7.5 1.1 9.4 0.0 9.2 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 CBZ29966.1 - 3.2e-11 43.3 4.2 0.00044 20.4 0.0 6.7 5 2 2 7 7 7 4 HEAT repeats Vac14_Fab1_bd PF12755.2 CBZ29966.1 - 0.0025 18.1 2.7 0.68 10.3 0.0 4.5 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region Pro_isomerase PF00160.16 CBZ29967.1 - 1.3e-44 152.0 0.1 1.6e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YfkB PF08756.5 CBZ29968.1 - 0.078 12.5 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 YfkB-like domain GTPase_Cys_C PF12631.2 CBZ29968.1 - 0.11 12.8 0.3 20 5.6 0.0 2.3 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Tropomyosin_1 PF12718.2 CBZ29968.1 - 0.74 9.6 4.4 6.5 6.5 0.0 2.1 2 0 0 2 2 2 0 Tropomyosin like C8 PF08742.6 CBZ29969.1 - 0.091 13.0 0.9 0.18 12.0 0.6 1.5 1 0 0 1 1 1 0 C8 domain Monellin PF09200.5 CBZ29970.1 - 0.18 11.4 0.5 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Monellin PIGA PF08288.7 CBZ29971.1 - 7.4e-38 128.8 0.1 1.6e-37 127.7 0.0 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CBZ29971.1 - 4e-29 101.2 0.0 6.3e-29 100.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CBZ29971.1 - 8.1e-17 61.4 0.2 3.1e-16 59.6 0.2 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CBZ29971.1 - 2.6e-14 53.6 0.0 5.6e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CBZ29971.1 - 5.5e-14 52.4 0.0 9.8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBZ29971.1 - 0.011 16.0 0.2 0.031 14.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 ThiI PF02568.9 CBZ29972.1 - 2e-46 157.9 0.1 3.3e-46 157.2 0.1 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Aminotran_5 PF00266.14 CBZ29972.1 - 1.4e-28 99.7 0.4 4.3e-14 52.0 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V tRNA_Me_trans PF03054.11 CBZ29972.1 - 0.00011 20.9 0.1 0.00024 19.8 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 CBZ29972.1 - 0.0027 16.9 0.5 0.052 12.8 0.0 2.5 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC DNA_pol_B PF00136.16 CBZ29973.1 - 9.4e-141 469.7 0.0 1.3e-140 469.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CBZ29973.1 - 6.8e-75 251.9 0.0 1.3e-74 251.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CBZ29973.1 - 1.1e-21 76.5 8.9 3e-21 75.2 6.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 CBZ29973.1 - 0.066 13.0 0.2 0.28 10.9 0.1 2.0 1 1 0 1 1 1 0 RNase_H superfamily zinc-ribbons_6 PF07191.7 CBZ29973.1 - 0.77 9.5 7.7 3 7.6 0.3 3.1 3 0 0 3 3 3 0 zinc-ribbons zf-RING-like PF08746.6 CBZ29973.1 - 2.3 8.2 8.8 7 6.7 1.2 3.2 2 0 0 2 2 2 0 RING-like domain SNF2_N PF00176.18 CBZ29974.1 - 1.3e-79 267.0 0.2 1.1e-78 264.1 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 CBZ29974.1 - 2e-21 75.8 0.6 5.7e-21 74.4 0.4 1.8 1 0 0 1 1 1 1 SLIDE Helicase_C PF00271.26 CBZ29974.1 - 1.4e-16 60.0 0.0 2e-15 56.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CBZ29974.1 - 3.2e-06 27.0 0.3 7e-05 22.7 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CBZ29974.1 - 6.5e-05 22.4 0.0 0.00021 20.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CBZ29974.1 - 0.003 16.4 0.0 0.0079 15.0 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 HAND PF09110.6 CBZ29974.1 - 0.0034 17.7 6.7 0.012 16.0 4.7 2.0 1 0 0 1 1 1 1 HAND Pkinase PF00069.20 CBZ29975.1 - 3.6e-66 222.9 0.0 5.5e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29975.1 - 1.2e-39 135.9 0.0 2e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.1 CBZ29975.1 - 5.1e-12 45.7 1.3 5e-06 26.5 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ29975.1 - 1.7e-10 39.4 0.8 0.035 13.4 0.1 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CBZ29975.1 - 2.8e-09 36.4 2.5 0.0003 20.3 0.4 3.1 3 0 0 3 3 3 2 EF-hand domain pair Kinase-like PF14531.1 CBZ29975.1 - 4.8e-09 35.6 0.0 2.3e-08 33.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like EF-hand_6 PF13405.1 CBZ29975.1 - 6.9e-08 31.7 0.7 0.07 13.0 0.1 5.1 3 1 1 4 4 4 2 EF-hand domain RIO1 PF01163.17 CBZ29975.1 - 2e-05 24.0 1.5 4.6e-05 22.8 1.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 CBZ29975.1 - 0.0075 15.3 0.1 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ29975.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family TPR_12 PF13424.1 CBZ29976.1 - 1.1e-18 66.9 16.5 2.7e-08 33.6 0.8 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ29976.1 - 4.9e-14 51.7 4.9 1.9e-06 27.4 0.0 3.5 3 1 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 CBZ29976.1 - 7.6e-13 47.4 8.1 0.0097 15.4 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ29976.1 - 6.5e-10 38.1 11.7 0.056 13.3 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat Apc5 PF12862.2 CBZ29976.1 - 3.2e-05 23.6 3.7 0.018 14.8 0.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_8 PF13181.1 CBZ29976.1 - 0.00077 19.0 2.6 22 5.1 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 CBZ29976.1 - 0.025 14.5 0.3 0.072 13.0 0.2 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat RPN7 PF10602.4 CBZ29976.1 - 0.026 13.9 0.8 1.3 8.3 0.0 2.6 1 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_7 PF13176.1 CBZ29976.1 - 0.038 13.7 6.1 47 4.1 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ29976.1 - 0.12 12.3 2.5 2.9 7.9 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ29976.1 - 0.15 11.9 1.5 3.1 7.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat MIF PF01187.13 CBZ29978.1 - 1.2e-11 44.6 0.0 1.3e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MIF PF01187.13 CBZ29979.1 - 3.3e-09 36.8 0.0 3.6e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Topo_C_assoc PF14370.1 CBZ29979.1 - 0.041 13.5 0.1 0.095 12.3 0.0 1.6 2 0 0 2 2 2 0 C-terminal topoisomerase domain OTT_1508_deam PF14441.1 CBZ29980.1 - 2.8e-11 43.4 0.0 3.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase LisH PF08513.6 CBZ29982.1 - 0.021 14.5 0.7 0.061 13.1 0.1 2.1 2 0 0 2 2 2 0 LisH DOT1 PF08123.8 CBZ29983.1 - 1.7e-14 53.6 0.0 2.4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 CBZ29983.1 - 0.00018 21.4 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ29983.1 - 0.00042 20.8 0.0 0.00059 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ29983.1 - 0.0025 17.4 0.0 0.0037 16.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ29983.1 - 0.039 14.4 0.0 0.064 13.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 CBZ29983.1 - 0.046 12.7 0.0 0.093 11.7 0.0 1.6 1 1 0 1 1 1 0 Putative methyltransferase DER1 PF04511.10 CBZ29984.1 - 2.2e-32 112.1 12.0 2.7e-32 111.8 8.3 1.0 1 0 0 1 1 1 1 Der1-like family Pkinase PF00069.20 CBZ29987.1 - 1.2e-53 181.8 0.0 1.7e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ29987.1 - 1.3e-24 86.6 0.0 1.9e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ29987.1 - 1.2e-05 25.2 0.0 6e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 CBZ29987.1 - 0.086 11.6 0.3 0.19 10.4 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ras PF00071.17 CBZ29988.1 - 6.7e-51 171.8 0.0 7.9e-51 171.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CBZ29988.1 - 1.5e-17 64.2 0.0 2.4e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CBZ29988.1 - 3.2e-16 59.0 0.0 3.9e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CBZ29988.1 - 8.2e-07 28.4 0.0 1.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CBZ29988.1 - 8.2e-06 25.7 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBZ29988.1 - 0.00018 20.7 0.1 0.00091 18.4 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CBZ29988.1 - 0.00066 19.1 0.0 0.0043 16.4 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 CBZ29988.1 - 0.0031 17.1 0.3 0.0063 16.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 CBZ29988.1 - 0.0035 16.9 0.2 0.015 14.8 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 CBZ29988.1 - 0.0051 16.8 1.8 0.026 14.5 0.4 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 CBZ29988.1 - 0.0053 16.2 1.3 0.021 14.3 0.9 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain DAP3 PF10236.4 CBZ29988.1 - 0.012 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_10 PF12846.2 CBZ29988.1 - 0.021 14.2 0.5 0.032 13.6 0.3 1.6 1 1 0 1 1 1 0 AAA-like domain SRPRB PF09439.5 CBZ29988.1 - 0.023 13.9 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MCM PF00493.18 CBZ29988.1 - 0.024 13.4 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family ABC_tran PF00005.22 CBZ29988.1 - 0.049 13.9 0.9 0.12 12.6 0.3 1.8 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 CBZ29988.1 - 0.078 13.1 0.0 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 CBZ29988.1 - 0.082 11.8 0.2 0.17 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 CBZ29988.1 - 0.11 12.7 0.1 0.17 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CBZ29988.1 - 0.13 12.0 0.0 0.39 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) YTH PF04146.10 CBZ29988.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.5 1 1 0 1 1 1 0 YT521-B-like domain G-alpha PF00503.15 CBZ29988.1 - 0.18 10.4 0.6 1.9 7.0 0.2 2.2 2 1 1 3 3 3 0 G-protein alpha subunit ABC_membrane_2 PF06472.10 CBZ29990.1 - 3.3e-66 223.3 0.5 4.6e-66 222.8 0.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CBZ29990.1 - 3.6e-18 66.1 0.0 8e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CBZ29990.1 - 0.00055 20.0 0.0 0.0029 17.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CBZ29990.1 - 0.0038 16.4 0.0 0.15 11.3 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CBZ29990.1 - 0.0041 16.6 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 CBZ29990.1 - 0.0096 13.3 0.5 0.014 12.7 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) FtsK_SpoIIIE PF01580.13 CBZ29990.1 - 0.018 14.5 0.1 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 CBZ29990.1 - 0.033 13.8 0.1 0.31 10.6 0.0 2.5 3 0 0 3 3 3 0 NACHT domain Mg_chelatase PF01078.16 CBZ29990.1 - 0.034 13.3 0.1 0.081 12.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 CBZ29990.1 - 0.054 12.9 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 CBZ29990.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 CBZ29990.1 - 0.1 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBZ29990.1 - 0.13 12.4 1.9 1.3 9.1 0.1 3.1 4 0 0 4 4 4 0 AAA domain DUF87 PF01935.12 CBZ29990.1 - 0.17 11.7 0.3 0.33 10.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 NOG1 PF06858.9 CBZ29991.1 - 2e-28 97.9 0.0 1.2e-27 95.4 0.0 2.2 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 CBZ29991.1 - 1.3e-24 85.6 6.4 1.7e-24 85.2 3.6 1.9 2 0 0 2 2 2 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 CBZ29991.1 - 1.8e-16 60.1 0.0 4.1e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ29991.1 - 4.3e-09 35.8 0.0 9e-09 34.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CBZ29991.1 - 4.3e-05 23.9 0.0 0.00012 22.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 CBZ29991.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 AIG1 family IQ PF00612.22 CBZ29992.1 - 0.0012 18.2 0.0 0.0043 16.5 0.0 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1353 PF07087.6 CBZ29992.1 - 0.098 12.1 0.5 0.37 10.3 0.1 2.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1353) FliT PF05400.8 CBZ29992.1 - 0.14 12.6 5.9 0.93 9.9 0.1 3.0 2 1 1 3 3 3 0 Flagellar protein FliT FOP_dimer PF09398.5 CBZ29994.1 - 2.7e-11 43.3 0.0 5e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH PF08513.6 CBZ29994.1 - 0.0031 17.2 0.1 0.006 16.3 0.1 1.5 1 0 0 1 1 1 1 LisH Snf7 PF03357.16 CBZ29995.1 - 2.5e-18 66.0 11.2 2.5e-18 66.0 7.8 1.8 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.9 CBZ29995.1 - 0.011 15.1 2.4 0.054 12.8 1.6 2.0 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Baculo_E25 PF05274.6 CBZ29995.1 - 0.033 13.7 0.1 0.059 12.9 0.1 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 CAF1C_H4-bd PF12265.3 CBZ29996.1 - 6.1e-18 64.5 0.0 1.3e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 CBZ29996.1 - 1.1e-08 34.6 6.3 0.0036 17.1 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2457 PF10446.4 CBZ29996.1 - 3.2 6.3 33.0 2.2 6.8 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Pho88 PF10032.4 CBZ29997.1 - 3.9e-50 169.7 0.0 4.5e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pribosyltran_N PF13793.1 CBZ29998.1 - 1.9e-39 134.0 0.2 7e-38 128.9 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CBZ29998.1 - 1.6e-22 80.1 1.0 8.8e-22 77.7 0.2 2.1 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CBZ29998.1 - 2.3e-13 49.9 0.1 4.8e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CBZ29998.1 - 0.0033 16.6 0.2 0.0057 15.8 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF3439 PF11921.3 CBZ30000.1 - 0.085 12.6 1.7 0.61 9.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ribosomal_L37e PF01907.14 CBZ30001.1 - 5.1e-27 93.4 8.6 8.5e-27 92.7 5.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e zinc_ribbon_6 PF14599.1 CBZ30001.1 - 0.037 13.8 0.5 0.057 13.2 0.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon DZR PF12773.2 CBZ30001.1 - 0.09 12.6 0.6 0.15 11.8 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF3279 PF11682.3 CBZ30003.1 - 0.092 12.3 0.7 0.19 11.2 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) Pkinase PF00069.20 CBZ30004.1 - 5.9e-60 202.6 0.0 8.9e-60 202.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30004.1 - 8.6e-39 133.1 0.0 1.1e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ30004.1 - 2.6e-08 33.1 0.0 4.5e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 CBZ30004.1 - 3.4e-07 30.4 0.0 2.5e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 CBZ30004.1 - 0.0035 17.4 0.0 0.079 13.1 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CBZ30004.1 - 0.03 14.5 0.7 0.4 10.9 0.5 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain PH_3 PF14593.1 CBZ30004.1 - 0.08 12.8 0.0 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 PH domain Skp1 PF01466.14 CBZ30005.1 - 0.0024 17.8 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain PEN-2 PF10251.4 CBZ30006.1 - 2e-06 27.9 5.1 2.7e-06 27.4 3.6 1.4 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase 7tm_2 PF00002.19 CBZ30006.1 - 0.0017 17.4 2.8 0.002 17.2 2.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF4231 PF14015.1 CBZ30006.1 - 0.079 12.9 0.1 0.18 11.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Peptidase_C2 PF00648.16 CBZ30007.1 - 3.1e-27 95.3 0.0 5.7e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 CBZ30007.1 - 5.9e-12 45.4 0.0 1.1e-06 28.2 0.0 3.4 3 0 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.13 CBZ30007.1 - 2.6e-05 23.9 0.2 5.9e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 CBZ30007.1 - 0.031 13.9 0.2 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 TPR repeat Arm PF00514.18 CBZ30009.1 - 2.6e-06 27.0 4.4 0.33 10.8 0.0 5.2 4 1 0 4 4 4 4 Armadillo/beta-catenin-like repeat Nup84_Nup100 PF04121.8 CBZ30010.1 - 0.00086 17.1 0.0 0.36 8.4 0.0 2.3 2 0 0 2 2 2 2 Nuclear pore protein 84 / 107 Peptidase_M23 PF01551.17 CBZ30010.1 - 0.13 12.2 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Peptidase family M23 Arm_2 PF04826.8 CBZ30011.1 - 0.015 14.3 0.0 0.045 12.8 0.0 1.7 2 0 0 2 2 2 0 Armadillo-like HEAT PF02985.17 CBZ30011.1 - 0.096 12.8 0.6 7.8 6.8 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat Nucleoside_tran PF01733.13 CBZ30012.1 - 0.024 13.7 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoside transporter DUF912 PF06024.7 CBZ30012.1 - 0.088 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pkinase PF00069.20 CBZ30013.1 - 4e-48 163.8 0.1 6.2e-38 130.4 0.0 2.6 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30013.1 - 4.8e-28 97.9 0.2 1.2e-19 70.4 0.1 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase E1-E2_ATPase PF00122.15 CBZ30015.1 - 7.8e-47 159.2 1.0 7.8e-47 159.2 0.7 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CBZ30015.1 - 1.3e-39 136.8 1.9 1.8e-39 136.3 0.7 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CBZ30015.1 - 8.9e-35 118.6 5.6 1.8e-16 60.0 0.1 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 CBZ30015.1 - 1.5e-15 57.8 0.0 3.7e-15 56.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CBZ30015.1 - 1.3e-06 28.1 0.2 2.5e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.1 CBZ30015.1 - 0.048 13.8 1.7 0.12 12.5 0.2 2.6 2 0 0 2 2 2 0 CoA binding domain His_Phos_1 PF00300.17 CBZ30016.1 - 2.1e-24 86.4 0.2 2.4e-22 79.7 0.0 2.5 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.17 CBZ30017.1 - 1.5e-19 70.6 0.0 5e-19 68.9 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-HIT PF04438.11 CBZ30018.1 - 5.9e-07 29.0 12.9 1.1e-06 28.0 8.9 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 CBZ30018.1 - 0.11 12.3 13.6 0.22 11.4 9.4 1.5 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.19 CBZ30018.1 - 1 9.3 7.4 2 8.3 5.1 1.5 1 0 0 1 1 1 0 B-box zinc finger Kinesin PF00225.18 CBZ30020.1 - 1.4e-81 273.8 0.6 2.3e-81 273.1 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain TMPIT PF07851.8 CBZ30020.1 - 6.3 5.7 6.0 5.2 6.0 0.8 2.3 2 0 0 2 2 2 0 TMPIT-like protein WD40 PF00400.27 CBZ30021.1 - 1e-07 31.5 11.8 0.023 14.5 0.3 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF3312 PF11768.3 CBZ30021.1 - 0.00042 18.6 0.0 0.00072 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Acid_PPase PF12689.2 CBZ30022.1 - 5.8e-49 165.9 0.0 6.7e-49 165.7 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.21 CBZ30022.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ30022.1 - 0.061 13.4 0.0 0.069 13.3 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TMF_TATA_bd PF12325.3 CBZ30023.1 - 0.057 13.1 1.9 0.75 9.5 0.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tup_N PF08581.5 CBZ30023.1 - 0.33 11.1 4.7 0.32 11.2 0.2 2.4 2 0 0 2 2 2 0 Tup N-terminal FH2 PF02181.18 CBZ30023.1 - 1.7 7.4 3.2 19 4.0 0.6 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain IncA PF04156.9 CBZ30023.1 - 5.8 6.4 9.3 16 5.0 0.1 3.4 3 0 0 3 3 3 0 IncA protein DUF1279 PF06916.8 CBZ30027.1 - 0.15 12.3 0.3 0.15 12.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) DUF1279 PF06916.8 CBZ30028.1 - 0.0037 17.5 0.1 0.0076 16.5 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) YlaC PF10777.4 CBZ30028.1 - 0.029 13.9 0.3 0.04 13.4 0.2 1.3 1 0 0 1 1 1 0 Inner membrane protein YlaC PaaSYMP PF14738.1 CBZ30029.1 - 1.2e-47 161.4 2.9 1.2e-47 161.4 2.0 2.3 2 1 0 2 2 2 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 BAF1_ABF1 PF04684.8 CBZ30030.1 - 1.2 7.8 5.8 1.6 7.4 4.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Baculo_IE-1 PF05290.6 CBZ30032.1 - 0.00044 19.9 1.7 0.00073 19.2 1.2 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.1 CBZ30032.1 - 0.31 10.7 14.3 0.54 9.9 9.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CBZ30032.1 - 2.5 7.9 13.8 4.1 7.3 9.6 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CBZ30032.1 - 4.4 7.4 14.2 7 6.7 9.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CBZ30032.1 - 4.8 6.8 12.5 12 5.5 8.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_hydro_85 PF03644.8 CBZ30033.1 - 2.5e-100 335.6 0.0 3.5e-100 335.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Peptidase_C97 PF05903.9 CBZ30033.1 - 2.9e-24 85.5 0.0 5.2e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.5 CBZ30033.1 - 8.7e-12 44.6 0.0 2.8e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 PUB domain DUF3421 PF11901.3 CBZ30033.1 - 5e-05 23.0 0.4 0.013 15.2 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3421) Glyco_hydro_18 PF00704.23 CBZ30033.1 - 0.18 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 DUF1136 PF06582.7 CBZ30034.1 - 4.3e-06 26.2 28.1 2.1e+02 1.7 0.0 15.5 16 0 0 16 16 16 0 Repeat of unknown function (DUF1136) FlxA PF14282.1 CBZ30034.1 - 0.0027 17.6 3.8 0.0027 17.6 2.6 6.1 2 1 9 11 11 11 1 FlxA-like protein IZUMO PF15005.1 CBZ30034.1 - 4.7 7.2 11.9 28 4.7 0.1 5.7 2 1 9 11 11 11 0 Izumo sperm-egg fusion zf-MYND PF01753.13 CBZ30035.1 - 9.5e-08 31.7 11.3 9.5e-08 31.7 7.8 2.0 2 0 0 2 2 2 1 MYND finger Pkinase PF00069.20 CBZ30036.1 - 7.4e-55 185.8 0.0 1.9e-50 171.4 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30036.1 - 1.1e-39 136.0 0.0 5.2e-37 127.3 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ30036.1 - 4e-05 22.7 0.1 0.00014 20.9 0.0 1.8 2 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 CBZ30036.1 - 0.00035 19.6 0.0 0.00067 18.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CBZ30036.1 - 0.009 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CBZ30036.1 - 0.049 13.3 0.2 9.5 5.8 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Epimerase PF01370.16 CBZ30037.1 - 3.6e-37 128.0 0.0 5.9e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CBZ30037.1 - 2.2e-14 53.0 0.0 2.6e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase_Csub PF13950.1 CBZ30037.1 - 3.4e-12 46.1 0.0 6.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 CBZ30037.1 - 3.3e-09 35.8 0.0 1.8e-08 33.4 0.0 2.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CBZ30037.1 - 1.4e-08 34.0 0.0 4.4e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 CBZ30037.1 - 0.00013 21.7 0.0 0.00061 19.4 0.0 2.1 2 1 0 2 2 2 1 KR domain adh_short PF00106.20 CBZ30037.1 - 0.00047 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 CBZ30037.1 - 0.00084 18.3 0.0 0.0067 15.3 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain DUF1800 PF08811.6 CBZ30037.1 - 0.052 12.4 0.0 0.078 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) DUF4232 PF14016.1 CBZ30037.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) CDC45 PF02724.9 CBZ30039.1 - 6.6e-130 434.0 0.0 7.6e-130 433.8 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Ebola_NP PF05505.7 CBZ30039.1 - 0.19 9.7 2.2 0.34 8.9 1.5 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein 2HCT PF03390.10 CBZ30039.1 - 0.36 9.1 0.3 0.57 8.4 0.2 1.2 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family CoA_trans PF01144.18 CBZ30041.1 - 1.8e-97 324.7 1.5 8.3e-60 201.6 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 CBZ30041.1 - 0.0064 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain RabGAP-TBC PF00566.13 CBZ30042.1 - 8.6e-08 31.9 0.6 1.4e-07 31.2 0.4 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Rhodanese PF00581.15 CBZ30042.1 - 0.0053 17.0 0.0 0.015 15.6 0.0 1.8 1 1 0 1 1 1 1 Rhodanese-like domain NCA2 PF08637.5 CBZ30043.1 - 3.4e-37 127.9 0.0 3.2e-29 101.7 0.0 2.2 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 GRASP55_65 PF04495.9 CBZ30045.1 - 5.5e-45 152.7 0.0 3.6e-39 133.8 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain HSP90 PF00183.13 CBZ30046.1 - 4e-73 246.6 2.8 3e-72 243.7 0.4 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.1 CBZ30046.1 - 7.7e-13 48.2 0.1 1.7e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CBZ30046.1 - 1.3e-05 24.8 0.0 2.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ski_Sno PF02437.12 CBZ30046.1 - 0.077 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 SKI/SNO/DAC family MMR_HSR1 PF01926.18 CBZ30047.1 - 9.6e-19 67.4 0.1 1.4e-13 50.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ30047.1 - 4e-11 42.4 0.3 6.2e-09 35.3 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CBZ30047.1 - 3.1e-05 23.4 0.1 0.00061 19.2 0.0 2.5 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CBZ30047.1 - 0.0008 18.6 0.3 0.027 13.6 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBZ30047.1 - 0.0009 19.1 0.6 0.032 14.0 0.1 2.8 2 1 1 3 3 3 1 Dynamin family Taeniidae_ag PF05596.6 CBZ30047.1 - 0.0083 15.9 0.0 0.029 14.1 0.0 1.9 1 0 0 1 1 1 1 Taeniidae antigen ArgK PF03308.11 CBZ30047.1 - 0.026 13.3 0.1 0.068 11.9 0.0 1.7 1 0 0 1 1 1 0 ArgK protein RNA_helicase PF00910.17 CBZ30047.1 - 0.027 14.6 0.0 2.1 8.5 0.0 2.8 3 0 0 3 3 3 0 RNA helicase Miro PF08477.8 CBZ30047.1 - 0.03 14.8 0.1 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 CBZ30047.1 - 0.06 14.1 0.7 0.28 12.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain Diphthamide_syn PF01866.12 CBZ30048.1 - 3.2e-32 112.0 0.2 6.2e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 Putative diphthamide synthesis protein zf-MYND PF01753.13 CBZ30049.1 - 5.5e-09 35.7 49.9 2.4e-05 24.1 12.4 3.2 3 0 0 3 3 3 2 MYND finger Taeniidae_ag PF05596.6 CBZ30051.1 - 0.0069 16.1 0.5 0.22 11.3 0.0 2.8 2 0 0 2 2 2 1 Taeniidae antigen zf-C3HC PF07967.8 CBZ30052.1 - 0.045 13.5 3.1 0.82 9.4 0.1 2.6 3 0 0 3 3 3 0 C3HC zinc finger-like Tox-WTIP PF15654.1 CBZ30054.1 - 0.0064 16.0 0.1 0.023 14.2 0.1 1.9 1 0 0 1 1 1 1 Toxin with a conserved tryptophan and TIP tripeptide motif Bax1-I PF01027.15 CBZ30054.1 - 0.078 12.5 16.6 0.066 12.8 10.3 1.8 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 KorB PF08535.5 CBZ30055.1 - 0.0051 16.9 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 KorB domain Rad51 PF08423.6 CBZ30056.1 - 5.4e-24 84.4 1.1 4.8e-18 64.9 0.1 4.0 4 0 0 4 4 4 3 Rad51 AAA_25 PF13481.1 CBZ30056.1 - 9.4e-13 47.9 0.0 2.6e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CBZ30056.1 - 7.9e-05 21.8 0.2 0.00019 20.6 0.1 1.6 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.1 CBZ30056.1 - 0.0002 21.0 0.1 0.0008 19.1 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain RecA PF00154.16 CBZ30056.1 - 0.00025 20.2 0.0 0.00046 19.3 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA PF00004.24 CBZ30056.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Radial_spoke PF04712.7 CBZ30057.1 - 2.9e-09 36.2 0.0 3.4e-07 29.4 0.0 2.5 2 1 0 2 2 2 2 Radial spokehead-like protein UDPGP PF01704.13 CBZ30059.1 - 1.4e-25 89.6 0.0 3.5e-25 88.3 0.0 1.4 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CBZ30059.1 - 0.023 14.7 0.1 0.074 13.1 0.1 1.9 1 0 0 1 1 1 0 MobA-like NTP transferase domain NUC173 PF08161.7 CBZ30060.1 - 1.1e-10 41.2 0.2 8.2e-10 38.3 0.1 2.5 2 0 0 2 2 2 1 NUC173 domain Peptidase_M32 PF02074.10 CBZ30061.1 - 1.2e-125 420.0 0.0 1.3e-125 419.8 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Iso_dh PF00180.15 CBZ30062.1 - 7.8e-106 353.9 0.0 9.7e-106 353.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 CBZ30062.1 - 0.0063 15.7 0.1 0.0096 15.1 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthetic protein PdxA Kinesin PF00225.18 CBZ30063.1 - 8.5e-103 343.5 0.0 1.5e-102 342.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Miro PF08477.8 CBZ30063.1 - 0.00013 22.4 0.0 0.00042 20.7 0.0 2.0 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 CBZ30063.1 - 0.00045 20.3 0.6 0.14 12.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CBZ30063.1 - 0.0019 18.2 0.2 0.055 13.4 0.0 3.1 3 0 0 3 3 2 1 AAA ATPase domain Ras PF00071.17 CBZ30063.1 - 0.0023 17.3 0.0 0.68 9.3 0.0 2.9 3 0 0 3 3 3 1 Ras family SmpA_OmlA PF04355.8 CBZ30063.1 - 0.0024 17.4 0.1 0.23 11.0 0.1 2.6 1 1 1 2 2 2 1 SmpA / OmlA family AAA_29 PF13555.1 CBZ30063.1 - 0.0031 17.0 0.0 0.11 12.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 CBZ30063.1 - 0.0079 15.3 0.1 0.034 13.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 CPT PF07931.7 CBZ30063.1 - 0.019 14.5 0.0 0.059 12.9 0.0 1.8 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Mg_chelatase PF01078.16 CBZ30063.1 - 0.02 14.0 0.0 0.99 8.5 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 CBZ30063.1 - 0.024 14.1 2.9 0.67 9.3 0.0 3.4 4 0 0 4 4 4 0 FtsK/SpoIIIE family AAA_28 PF13521.1 CBZ30063.1 - 0.03 14.2 1.6 0.059 13.3 0.2 2.3 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 CBZ30063.1 - 0.062 12.7 2.2 0.71 9.2 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain ABC_tran PF00005.22 CBZ30063.1 - 0.12 12.7 0.3 0.56 10.5 0.1 2.2 2 0 0 2 2 2 0 ABC transporter DUF815 PF05673.8 CBZ30063.1 - 0.2 10.5 0.1 0.51 9.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.18 CBZ30063.1 - 0.25 11.2 0.4 4.6 7.2 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 CBZ30063.1 - 0.39 10.9 1.1 20 5.4 0.0 3.4 4 0 0 4 4 3 0 RNA helicase DUF87 PF01935.12 CBZ30063.1 - 0.68 9.7 0.8 16 5.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 Peptidase_M17 PF00883.16 CBZ30064.1 - 2.2e-87 292.8 0.5 3.8e-87 292.0 0.0 1.6 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Auxin_resp PF06507.8 CBZ30064.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Auxin response factor SBP_bac_5 PF00496.17 CBZ30064.1 - 0.21 10.3 0.0 0.34 9.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle NapE PF06796.6 CBZ30065.1 - 0.31 10.3 2.6 0.5 9.7 1.8 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE 3HCDH_N PF02737.13 CBZ30068.1 - 4.4e-42 143.7 0.0 7.9e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH PF00378.15 CBZ30068.1 - 1.4e-35 122.6 0.0 2.3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family 3HCDH PF00725.17 CBZ30068.1 - 1.8e-18 66.7 0.1 1.3e-09 38.3 0.0 3.5 3 0 0 3 3 3 3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Pyr_redox_2 PF07992.9 CBZ30068.1 - 0.0028 17.5 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBZ30068.1 - 0.0074 15.2 0.0 0.017 14.0 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CBZ30068.1 - 0.0096 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding ApbA PF02558.11 CBZ30068.1 - 0.049 13.0 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 CBZ30068.1 - 0.054 13.9 0.0 0.17 12.3 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CBZ30068.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 CBZ30068.1 - 0.083 12.7 0.1 0.22 11.3 0.1 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CBZ30068.1 - 0.15 12.1 0.0 0.45 10.6 0.0 1.7 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_M16_C PF05193.16 CBZ30069.1 - 2.1e-21 76.4 0.0 3.5e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CBZ30069.1 - 3.6e-06 26.8 0.0 7.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SRPRB PF09439.5 CBZ30070.1 - 1e-18 67.1 0.0 1.7e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CBZ30070.1 - 9.5e-06 25.1 0.0 2.9e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CBZ30070.1 - 9e-05 22.4 0.0 0.001 19.0 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ30070.1 - 0.0016 18.9 0.0 0.0034 17.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF463 PF04317.7 CBZ30070.1 - 0.025 13.1 0.1 4.6 5.7 0.0 2.4 2 0 0 2 2 2 0 YcjX-like family, DUF463 AAA_16 PF13191.1 CBZ30070.1 - 0.026 14.5 4.5 0.75 9.7 0.1 3.1 2 1 0 3 3 3 0 AAA ATPase domain cobW PF02492.14 CBZ30070.1 - 0.027 13.9 0.0 0.065 12.6 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CBZ30070.1 - 0.028 14.2 0.0 0.081 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CBZ30070.1 - 0.038 14.1 0.1 0.14 12.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 CBZ30070.1 - 0.12 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 CBZ30070.1 - 0.13 11.4 0.5 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 WD40 PF00400.27 CBZ30071.1 - 1e-09 37.8 0.1 0.15 12.0 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat LIM PF00412.17 CBZ30072.1 - 5.8e-05 23.0 0.4 0.0001 22.2 0.3 1.4 1 0 0 1 1 1 1 LIM domain Fer4_2 PF12797.2 CBZ30072.1 - 0.6 10.1 4.6 4.6 7.3 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain ThiF PF00899.16 CBZ30073.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CBZ30073.1 - 0.093 12.3 0.0 0.27 10.8 0.0 1.8 1 0 0 1 1 1 0 MoeZ/MoeB domain PseudoU_synth_2 PF00849.17 CBZ30074.1 - 0.059 13.2 0.4 0.58 9.9 0.0 2.5 3 0 0 3 3 3 0 RNA pseudouridylate synthase PyrI_C PF02748.10 CBZ30074.1 - 0.07 12.5 0.2 5.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-CCHC_4 PF14392.1 CBZ30074.1 - 0.087 12.5 4.7 5.9 6.6 0.1 2.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 CBZ30074.1 - 1.4 9.0 8.2 9.7 6.3 1.0 3.1 2 0 0 2 2 2 0 Zinc knuckle Filament PF00038.16 CBZ30075.1 - 0.0019 17.7 10.3 0.0019 17.7 7.1 6.4 3 2 2 6 6 6 3 Intermediate filament protein DUF904 PF06005.7 CBZ30075.1 - 0.013 15.7 1.8 0.013 15.7 1.2 9.7 9 2 0 9 9 9 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 CBZ30075.1 - 0.18 11.7 0.1 0.18 11.7 0.0 8.9 11 1 1 12 12 12 0 bZIP transcription factor DnaJ PF00226.26 CBZ30077.1 - 9.7e-11 41.2 0.1 2.5e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 DnaJ domain DUF3359 PF11839.3 CBZ30077.1 - 0.052 13.8 4.9 0.12 12.7 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) Mnd1 PF03962.10 CBZ30077.1 - 0.17 11.5 4.7 0.29 10.7 3.3 1.3 1 0 0 1 1 1 0 Mnd1 family MAT1 PF06391.8 CBZ30077.1 - 2.8 7.4 5.8 3.9 6.9 4.0 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 MCM PF00493.18 CBZ30078.1 - 1.1e-111 372.8 0.0 1.7e-111 372.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CBZ30078.1 - 7.2e-16 58.7 0.0 1.9e-15 57.3 0.0 1.7 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CBZ30078.1 - 1.6e-08 33.9 0.6 5.9e-07 28.8 0.0 2.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CBZ30078.1 - 0.00023 20.7 0.0 0.0019 17.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 CBZ30078.1 - 0.0022 17.5 0.0 0.0053 16.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RPA_C PF08784.6 CBZ30078.1 - 0.0023 18.3 0.0 0.0066 16.8 0.0 1.8 1 0 0 1 1 1 1 Replication protein A C terminal AAA_5 PF07728.9 CBZ30078.1 - 0.028 14.1 0.0 0.14 11.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ30078.1 - 0.06 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Complex1_LYR PF05347.10 CBZ30079.1 - 3.4e-07 29.9 0.7 6.4e-07 29.0 0.5 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBZ30079.1 - 0.0032 17.6 1.3 0.0062 16.7 0.9 1.5 1 0 0 1 1 1 1 Complex1_LYR-like ketoacyl-synt PF00109.21 CBZ30080.1 - 6.5e-38 130.6 0.8 2.2e-37 128.9 0.6 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CBZ30080.1 - 3.4e-26 91.4 0.7 3.4e-26 91.4 0.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ETF PF01012.16 CBZ30081.1 - 0.052 13.2 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Electron transfer flavoprotein domain GTP_EFTU PF00009.22 CBZ30082.1 - 7.1e-33 113.6 0.0 2.3e-32 111.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CBZ30082.1 - 8.3e-15 54.6 0.0 2.2e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CBZ30082.1 - 6.2e-11 42.2 0.6 2.7e-07 30.5 0.0 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ30082.1 - 1.2e-06 28.4 0.0 4.5e-06 26.5 0.0 2.1 2 0 0 2 2 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CBZ30082.1 - 0.00052 20.0 0.2 0.00052 20.0 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain GTP_EFTU_D4 PF14578.1 CBZ30082.1 - 0.0014 18.2 0.2 0.004 16.7 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 CBZ30082.1 - 0.0018 17.8 0.0 0.0067 15.9 0.0 1.9 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein Miro PF08477.8 CBZ30082.1 - 0.0021 18.5 0.0 0.0091 16.4 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 CBZ30082.1 - 0.014 15.4 0.0 0.05 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 CBZ30082.1 - 0.016 14.3 0.0 0.057 12.6 0.0 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Ras PF00071.17 CBZ30082.1 - 0.02 14.3 0.0 0.13 11.6 0.0 2.2 1 1 0 1 1 1 0 Ras family DUF258 PF03193.11 CBZ30082.1 - 0.065 12.4 0.1 0.37 9.9 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CBZ30082.1 - 0.098 12.4 14.9 0.21 11.4 4.0 4.3 2 1 0 2 2 2 0 Dynamin family MIP-T3 PF10243.4 CBZ30082.1 - 0.19 10.1 33.5 0.32 9.4 23.2 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF4520 PF15016.1 CBZ30083.1 - 4.1e-26 90.3 0.1 6.2e-24 83.3 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4520) Corona_NS3b PF03053.9 CBZ30083.1 - 0.05 13.1 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 ORF3b coronavirus protein POLO_box PF00659.13 CBZ30083.1 - 0.16 11.9 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 POLO box duplicated region DUF2828 PF11443.3 CBZ30083.1 - 0.25 9.4 0.1 0.41 8.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) UQ_con PF00179.21 CBZ30085.1 - 1.5e-34 118.4 0.0 2.1e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ30085.1 - 0.0067 16.1 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Beach PF02138.13 CBZ30086.1 - 5.5e-87 291.6 0.0 9.2e-87 290.8 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.1 CBZ30086.1 - 4.7e-09 36.6 0.2 1.1e-08 35.4 0.2 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GTP_EFTU PF00009.22 CBZ30087.1 - 1.4e-20 73.5 0.0 3.6e-20 72.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ30087.1 - 9.3e-17 61.0 0.1 6.1e-16 58.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CBZ30087.1 - 0.0001 22.3 0.7 0.00026 21.0 0.5 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MobB PF03205.9 CBZ30087.1 - 0.004 16.8 0.2 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 CBZ30087.1 - 0.0087 15.5 0.1 1.1 8.7 0.0 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CBZ30087.1 - 0.046 13.6 0.0 0.19 11.6 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2536 PF10750.4 CBZ30088.1 - 0.0041 16.6 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2536) TFIIS_C PF01096.13 CBZ30089.1 - 6.3e-15 54.5 7.3 1.2e-14 53.6 5.0 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) PWWP PF00855.12 CBZ30089.1 - 7.8e-07 29.2 0.4 2.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 PWWP domain Baculo_LEF5_C PF11792.3 CBZ30089.1 - 0.14 11.5 0.8 0.3 10.5 0.6 1.6 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain PWWP PF00855.12 CBZ30090.1 - 1.5e-10 41.0 1.0 3e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.6 CBZ30090.1 - 2.3e-09 36.6 0.0 3.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Lar_restr_allev PF14354.1 CBZ30090.1 - 0.017 15.4 0.5 0.045 14.0 0.3 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar TFIIS_C PF01096.13 CBZ30090.1 - 0.039 13.6 1.5 0.1 12.2 1.0 1.8 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) zinc_ribbon_5 PF13719.1 CBZ30090.1 - 0.047 13.2 2.4 0.31 10.6 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-DNA_Pol PF08996.5 CBZ30090.1 - 0.089 12.1 0.4 0.23 10.8 0.3 1.6 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Zn_Tnp_IS1595 PF12760.2 CBZ30090.1 - 0.097 12.4 4.4 0.05 13.4 0.7 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 CBZ30090.1 - 0.11 11.6 0.6 1.7 7.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CBZ30090.1 - 0.17 11.6 2.7 0.86 9.3 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain FancD2 PF14631.1 CBZ30090.1 - 0.25 8.3 1.3 0.36 7.8 0.9 1.2 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease zinc_ribbon_2 PF13240.1 CBZ30090.1 - 5.2 6.6 6.6 4.9 6.7 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain CHAP PF05257.11 CBZ30091.1 - 1.4e-15 57.0 3.1 2.9e-15 56.0 2.1 1.5 1 1 0 1 1 1 1 CHAP domain Amidase_6 PF12671.2 CBZ30091.1 - 0.00048 20.2 0.8 0.0028 17.7 0.5 2.0 1 1 0 1 1 1 1 Putative amidase domain Y_phosphatase3 PF13350.1 CBZ30093.1 - 2.1e-38 132.1 0.8 2.8e-38 131.7 0.1 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 CBZ30093.1 - 2.7e-12 46.5 0.4 8e-12 45.1 0.3 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 CBZ30093.1 - 0.0051 16.1 0.1 0.0072 15.6 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CBZ30093.1 - 0.038 13.5 0.2 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain CHAP PF05257.11 CBZ30094.1 - 1.2e-12 47.5 0.1 2.9e-11 43.0 0.1 2.3 1 1 0 1 1 1 1 CHAP domain FeS PF04060.8 CBZ30094.1 - 0.086 12.4 0.2 0.23 11.0 0.2 1.7 1 0 0 1 1 1 0 Putative Fe-S cluster CHAP PF05257.11 CBZ30095.1 - 1.1e-05 25.0 0.3 0.0022 17.6 0.0 2.6 2 0 0 2 2 2 2 CHAP domain DUF3760 PF12586.3 CBZ30096.1 - 0.13 12.1 0.2 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Kinesin PF00225.18 CBZ30098.1 - 0.0011 17.8 0.0 0.0091 14.7 0.0 2.4 2 2 0 2 2 2 1 Kinesin motor domain TAP42 PF04177.7 CBZ30098.1 - 0.069 12.0 1.4 0.14 11.0 1.0 1.4 1 0 0 1 1 1 0 TAP42-like family P-II PF00543.17 CBZ30098.1 - 0.12 12.8 0.3 49 4.4 0.0 3.4 3 0 0 3 3 3 0 Nitrogen regulatory protein P-II Kinesin PF00225.18 CBZ30101.1 - 7.6e-07 28.1 0.1 0.13 10.9 0.0 4.6 5 1 0 5 5 5 3 Kinesin motor domain Sec8_exocyst PF04048.9 CBZ30101.1 - 0.009 15.6 0.5 0.19 11.3 0.0 2.9 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain vWA-TerF-like PF10138.4 CBZ30107.1 - 0.083 12.7 0.0 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 vWA found in TerF C terminus DUF1059 PF06348.6 CBZ30109.1 - 0.018 14.8 0.2 0.052 13.3 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) ABC_tran PF00005.22 CBZ30113.1 - 3.6e-10 40.2 0.0 0.00047 20.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SbcCD_C PF13558.1 CBZ30113.1 - 3.8e-05 23.5 1.1 0.00022 21.0 0.2 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 CBZ30113.1 - 0.064 13.4 0.0 0.4 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBZ30113.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 CBZ30113.1 - 0.15 12.0 0.0 8.1 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CBZ30113.1 - 0.2 10.8 0.0 0.41 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SMC_N PF02463.14 CBZ30113.1 - 0.83 8.8 0.9 7.9 5.6 0.0 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Tyr-DNA_phospho PF06087.7 CBZ30114.1 - 1e-65 222.1 0.0 1.3e-60 205.3 0.0 2.7 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase HTH_IclR PF09339.5 CBZ30116.1 - 5e-06 26.0 0.2 4.6 6.9 0.0 4.1 4 0 0 4 4 4 3 IclR helix-turn-helix domain SUKH-4 PF14435.1 CBZ30116.1 - 0.0004 20.1 6.8 3.3 7.3 0.0 4.8 5 0 0 5 5 5 3 SUKH-4 immunity protein RBD-FIP PF09457.5 CBZ30116.1 - 0.0046 16.7 0.0 1.1e+02 2.7 0.0 4.5 4 0 0 4 4 4 0 FIP domain SH2_2 PF14633.1 CBZ30118.1 - 2.3e-12 46.4 0.1 4e-12 45.6 0.1 1.3 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.1 CBZ30118.1 - 4.9e-12 45.6 0.0 4.6e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 HTH_5 PF01022.15 CBZ30118.1 - 0.048 13.3 0.1 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HHH_7 PF14635.1 CBZ30118.1 - 0.16 12.0 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Trypsin_2 PF13365.1 CBZ30121.1 - 2.6e-07 30.6 0.0 4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 CBZ30121.1 - 0.012 15.2 0.2 0.029 13.9 0.2 1.7 1 1 0 1 1 1 0 Trypsin DUF2094 PF09867.4 CBZ30121.1 - 0.048 13.5 0.1 0.087 12.7 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2094) Ribosomal_S13_N PF08069.7 CBZ30123.1 - 2.1e-24 85.1 1.7 2.1e-24 85.1 1.2 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CBZ30123.1 - 9.4e-22 76.5 0.4 1.4e-21 75.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 AAA_13 PF13166.1 CBZ30125.1 - 0.0033 15.9 0.0 0.35 9.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain HALZ PF02183.13 CBZ30125.1 - 0.031 14.0 2.5 2.4 7.9 0.1 3.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF948 PF06103.6 CBZ30125.1 - 0.05 13.4 3.2 5.3 6.9 0.3 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Sec8_exocyst PF04048.9 CBZ30125.1 - 0.91 9.1 4.4 9.8 5.8 0.5 2.6 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF4381 PF14316.1 CBZ30126.1 - 0.00068 19.7 0.6 1.8 8.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4381) PufQ PF05398.6 CBZ30126.1 - 0.013 15.5 0.2 9 6.4 0.0 2.6 2 0 0 2 2 2 0 PufQ cytochrome subunit Robl_LC7 PF03259.12 CBZ30126.1 - 0.11 12.0 2.8 11 5.6 0.1 2.8 2 0 0 2 2 2 0 Roadblock/LC7 domain HlyIII PF03006.15 CBZ30126.1 - 0.19 11.0 6.8 3.8 6.8 0.1 3.0 3 0 0 3 3 3 0 Haemolysin-III related DUF4131 PF13567.1 CBZ30126.1 - 1.4 8.3 6.1 15 4.8 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) LSM PF01423.17 CBZ30127.1 - 4.9e-13 48.4 0.1 7.1e-13 47.9 0.1 1.2 1 0 0 1 1 1 1 LSM domain Zip PF02535.17 CBZ30128.1 - 6.3e-33 114.1 16.9 9.9e-33 113.4 11.7 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Coatomer_WDAD PF04053.9 CBZ30129.1 - 2.4e-134 448.4 0.0 4.5e-134 447.5 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 CBZ30129.1 - 1e-42 142.4 1.7 8.8e-11 41.2 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat TPR_8 PF13181.1 CBZ30129.1 - 0.035 13.8 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.15 CBZ30129.1 - 0.069 12.7 0.1 1.9 8.1 0.0 2.5 1 1 0 2 2 2 0 Region in Clathrin and VPS EF-hand_7 PF13499.1 CBZ30130.1 - 5.6e-06 26.3 0.1 2.3e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 CBZ30130.1 - 6.4e-05 22.1 0.0 0.00016 20.8 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 CBZ30130.1 - 0.00025 20.6 0.0 0.003 17.3 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CBZ30130.1 - 0.0023 17.1 0.0 0.024 13.9 0.0 2.6 2 0 0 2 2 2 1 EF hand DUF2959 PF11172.3 CBZ30130.1 - 0.014 15.1 0.2 0.042 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Ribosomal_L44 PF00935.14 CBZ30131.1 - 2.8e-31 107.3 8.9 4.4e-31 106.7 6.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 RPA_interact_C PF14768.1 CBZ30131.1 - 0.11 12.9 0.7 0.66 10.4 0.5 1.9 1 1 0 1 1 1 0 Replication protein A interacting C-terminal ABC_tran PF00005.22 CBZ30134.1 - 3.7e-19 69.3 0.0 6.5e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 CBZ30134.1 - 0.0069 15.8 0.0 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBZ30134.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 CBZ30134.1 - 0.023 14.6 0.8 0.097 12.6 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.14 CBZ30134.1 - 0.11 11.7 0.0 1.8 7.7 0.0 1.8 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 CBZ30134.1 - 0.17 11.0 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBZ30134.1 - 0.18 12.6 0.0 0.62 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CBZ30134.1 - 0.27 11.1 0.1 0.65 9.9 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 CBZ30134.1 - 0.27 10.6 0.9 2.2 7.6 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain FA_desaturase PF00487.19 CBZ30135.1 - 3e-27 95.6 29.1 4.9e-27 94.9 20.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase adh_short PF00106.20 CBZ30136.1 - 1.1e-16 61.2 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBZ30136.1 - 7.6e-07 29.1 0.0 1.3e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBZ30136.1 - 0.00023 20.9 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBZ30136.1 - 0.0031 17.5 0.0 0.0064 16.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 CBZ30136.1 - 0.006 16.4 0.1 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1776 PF08643.5 CBZ30136.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) LRR_4 PF12799.2 CBZ30137.1 - 7.5e-15 54.1 0.6 0.0073 15.9 0.6 7.0 2 1 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ30137.1 - 4.9e-09 35.8 4.4 9.2e-05 22.1 0.0 5.4 3 1 2 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 CBZ30137.1 - 0.00034 20.3 12.5 80 3.7 0.0 8.5 8 2 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.28 CBZ30137.1 - 0.0011 18.7 12.4 4.3 7.7 0.2 7.4 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_5 PF13306.1 CBZ30137.1 - 0.059 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) LRR_7 PF13504.1 CBZ30137.1 - 1.6 9.2 17.1 46 4.8 0.0 7.9 8 1 1 9 9 9 0 Leucine rich repeat Pkinase PF00069.20 CBZ30138.1 - 7.9e-42 143.1 0.0 9.8e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30138.1 - 1.9e-24 86.1 0.0 2.3e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ30138.1 - 3.8e-07 29.3 0.0 2.9e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBZ30138.1 - 0.02 14.6 0.0 1.6 8.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 CBZ30138.1 - 0.18 11.3 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 CBZ30138.1 - 0.21 10.3 0.0 0.31 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DnaJ PF00226.26 CBZ30139.1 - 2.1e-14 52.9 0.0 3.9e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain CLPTM1 PF05602.7 CBZ30140.1 - 5e-124 414.3 0.0 6e-124 414.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) peroxidase PF00141.18 CBZ30142.1 - 4e-46 157.3 0.0 6.4e-46 156.6 0.0 1.3 1 1 0 1 1 1 1 Peroxidase zf-C2H2_6 PF13912.1 CBZ30142.1 - 0.024 14.5 0.3 0.045 13.6 0.2 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger G6PD_C PF02781.11 CBZ30143.1 - 1.2e-119 398.5 0.0 1.7e-119 398.0 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CBZ30143.1 - 1.3e-60 204.7 0.0 2.1e-60 204.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain HPP PF04982.8 CBZ30144.1 - 0.059 13.2 1.8 0.068 13.0 1.3 1.1 1 0 0 1 1 1 0 HPP family NCKAP5 PF15246.1 CBZ30146.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Herpes_UL52 PF03121.10 CBZ30146.1 - 0.75 9.5 7.2 1.5 8.5 5.0 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase ADK PF00406.17 CBZ30147.1 - 9.7e-52 174.8 0.0 1.2e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CBZ30147.1 - 6.8e-13 48.0 0.0 1.7e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CBZ30147.1 - 2.8e-07 31.3 0.1 5.2e-07 30.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ30147.1 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ30147.1 - 0.0051 16.7 0.1 0.18 11.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 CBZ30148.1 - 2e-26 92.6 0.0 2.6e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CBZ30148.1 - 8.9e-11 41.2 0.0 1.5e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CBZ30148.1 - 1.6e-06 28.9 0.0 2.1e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ30148.1 - 0.0029 17.8 0.0 0.006 16.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ30148.1 - 0.0034 17.2 0.0 0.0071 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CBZ30148.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MscS_porin PF12795.2 CBZ30148.1 - 0.027 13.7 0.1 0.056 12.7 0.1 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Perilipin PF03036.11 CBZ30148.1 - 0.095 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Perilipin family Ldh_1_C PF02866.13 CBZ30149.1 - 1.2e-14 54.4 0.0 1.3e-13 51.0 0.0 2.1 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CBZ30149.1 - 3e-12 46.5 0.0 5e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CBZ30149.1 - 0.048 12.7 0.1 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 CBZ30150.1 - 1.9e-44 150.8 0.0 2.6e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBZ30150.1 - 4.7e-43 146.9 0.0 7e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Semialdhyde_dh PF01118.19 CBZ30150.1 - 0.00022 21.5 0.0 0.00084 19.6 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CBZ30150.1 - 0.0031 16.2 0.0 0.0057 15.4 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 CBZ30150.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.14 CBZ30150.1 - 0.048 12.7 0.0 0.41 9.6 0.0 2.1 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 CBZ30151.1 - 1e-36 125.8 0.0 1.4e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBZ30151.1 - 1e-32 113.2 0.0 1.6e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CBZ30151.1 - 0.00039 19.2 0.0 0.00058 18.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CBZ30151.1 - 0.0028 17.9 0.0 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CBZ30151.1 - 0.069 12.2 0.0 0.46 9.5 0.0 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 CBZ30152.1 - 5.3e-41 139.7 0.0 7.1e-41 139.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CBZ30152.1 - 6.2e-38 130.2 0.0 8.2e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CBZ30152.1 - 0.044 12.4 0.0 0.067 11.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3756 PF12581.3 CBZ30152.1 - 0.25 11.0 1.5 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) Nop25 PF09805.4 CBZ30153.1 - 6.5e-08 32.7 14.4 6.5e-08 32.7 10.0 3.4 2 1 2 4 4 4 1 Nucleolar protein 12 (25kDa) CP12 PF02672.10 CBZ30153.1 - 0.46 10.9 0.1 0.46 10.9 0.1 2.5 4 0 0 4 4 4 0 CP12 domain Methyltransf_26 PF13659.1 CBZ30155.1 - 0.0073 16.3 2.1 0.013 15.5 0.4 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ30155.1 - 0.058 13.9 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF1935 PF09149.5 CBZ30156.1 - 3.6e-120 393.1 5.0 6.2e-32 109.6 0.1 4.0 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) Glyco_hydro_98C PF08307.6 CBZ30156.1 - 0.016 14.5 0.5 0.056 12.7 0.0 2.0 3 0 0 3 3 3 0 Glycosyl hydrolase family 98 C-terminal domain DUF1935 PF09149.5 CBZ30157.1 - 7.2e-117 382.5 0.2 3.2e-31 107.3 0.0 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) CS PF04969.11 CBZ30158.1 - 9.4e-10 38.9 0.0 1.4e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 CS domain EMP24_GP25L PF01105.19 CBZ30159.1 - 2.5e-10 40.3 0.3 5.4e-10 39.2 0.2 1.6 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2741 PF10890.3 CBZ30159.1 - 0.038 14.1 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) Reo_sigmaC PF04582.7 CBZ30160.1 - 0.21 10.6 9.5 0.12 11.5 0.7 3.2 2 1 1 3 3 3 0 Reovirus sigma C capsid protein RIIa PF02197.12 CBZ30163.1 - 1e-06 28.0 0.5 1.5e-06 27.5 0.4 1.3 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.8 CBZ30163.1 - 9.6e-05 21.7 0.1 0.0002 20.7 0.0 1.6 1 1 0 1 1 1 1 Dpy-30 motif Sigma70_r2 PF04542.9 CBZ30163.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-70 region 2 RNaseH_C PF09293.5 CBZ30163.1 - 0.056 13.3 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 T4 RNase H, C terminal DUF3455 PF11937.3 CBZ30163.1 - 0.084 12.7 0.1 0.092 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Pyr_redox_2 PF07992.9 CBZ30164.1 - 1.9e-07 31.1 0.0 7.8e-06 25.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ30164.1 - 0.0014 18.5 0.1 0.0039 17.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 CBZ30164.1 - 0.0033 16.3 0.3 0.0064 15.4 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 CBZ30164.1 - 0.005 15.7 3.5 0.02 13.8 0.1 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 CBZ30164.1 - 0.037 12.6 0.3 0.058 12.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 CBZ30164.1 - 0.059 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 CBZ30164.1 - 0.065 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 CBZ30164.1 - 0.074 11.5 1.1 0.72 8.2 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein DUF3115 PF11312.3 CBZ30164.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) TrkA_N PF02254.13 CBZ30164.1 - 0.16 12.0 0.3 0.48 10.4 0.2 1.9 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 CBZ30164.1 - 0.22 11.2 3.4 0.63 9.7 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding DUF3446 PF11928.3 CBZ30164.1 - 3.6 7.8 10.5 15 5.8 2.6 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3446) Peptidase_C2 PF00648.16 CBZ30165.1 - 0.0015 17.5 0.0 0.0034 16.4 0.0 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease Mon1 PF03164.9 CBZ30166.1 - 3.9e-25 88.3 0.0 6.1e-16 58.0 0.0 2.7 2 1 0 2 2 2 2 Trafficking protein Mon1 WD40 PF00400.27 CBZ30167.1 - 1.3e-18 66.0 4.3 0.00034 20.3 0.0 6.5 7 1 0 7 7 7 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CBZ30167.1 - 0.13 10.9 0.0 1.7 7.3 0.0 2.5 3 0 0 3 3 3 0 Nup133 N terminal like PseudoU_synth_1 PF01416.15 CBZ30168.1 - 4.2e-20 72.1 0.0 4.2e-11 43.2 0.0 3.5 2 2 0 2 2 2 2 tRNA pseudouridine synthase Synaphin PF05835.7 CBZ30168.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.4 4 0 0 4 4 4 0 Synaphin protein START PF01852.14 CBZ30169.1 - 0.016 14.5 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 START domain DS PF01916.12 CBZ30170.1 - 2e-52 178.1 0.0 2e-37 128.9 0.0 4.1 4 0 0 4 4 4 4 Deoxyhypusine synthase AAA PF00004.24 CBZ30171.1 - 9.4e-10 38.7 0.0 2.8e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ30171.1 - 1.3e-06 29.2 0.0 3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ30171.1 - 1.7e-06 27.8 0.0 5.1e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ30171.1 - 3.9e-05 23.7 0.0 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 CBZ30171.1 - 0.0028 17.6 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CBZ30171.1 - 0.0042 16.9 0.0 0.012 15.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain DUF815 PF05673.8 CBZ30171.1 - 0.0047 15.8 0.0 0.0078 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 CBZ30171.1 - 0.0057 16.0 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ30171.1 - 0.0067 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CBZ30171.1 - 0.0087 16.2 0.0 0.024 14.7 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.1 CBZ30171.1 - 0.0099 16.1 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ30171.1 - 0.01 15.5 1.5 0.017 14.8 0.0 2.1 2 0 0 2 2 1 0 Part of AAA domain KAP_NTPase PF07693.9 CBZ30171.1 - 0.021 13.8 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.1 CBZ30171.1 - 0.022 14.3 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 CBZ30171.1 - 0.043 13.4 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CBZ30171.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 CBZ30171.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 CBZ30171.1 - 0.14 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Miro PF08477.8 CBZ30171.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein eIF-5_eIF-2B PF01873.12 CBZ30172.1 - 4.6e-32 110.3 0.1 8.3e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CBZ30172.1 - 3.1e-05 23.8 0.0 0.00011 22.0 0.0 1.9 1 1 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon zf-CHY PF05495.7 CBZ30172.1 - 0.0034 17.4 1.2 0.0034 17.4 0.8 1.6 2 0 0 2 2 2 1 CHY zinc finger RNA_pol_Rpb1_5 PF04998.12 CBZ30173.1 - 1.3e-79 267.3 0.0 2.6e-79 266.3 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CBZ30173.1 - 5.9e-62 208.4 0.0 1.1e-61 207.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 CBZ30173.1 - 4e-54 184.1 0.0 6.4e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 CBZ30173.1 - 1.7e-31 109.1 0.0 4.2e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CBZ30173.1 - 7.7e-31 106.0 0.0 2e-30 104.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 COG6 PF06419.6 CBZ30174.1 - 2.2e-38 131.8 0.0 1.6e-35 122.3 0.0 3.3 3 1 0 3 3 3 2 Conserved oligomeric complex COG6 DASH_Dad3 PF08656.5 CBZ30174.1 - 0.042 13.5 0.1 3.8 7.2 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF1241 PF06840.6 CBZ30174.1 - 0.065 12.4 0.1 0.77 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) Occludin_ELL PF07303.8 CBZ30174.1 - 0.31 11.7 2.9 0.43 11.3 0.6 2.2 1 1 1 2 2 2 0 Occludin homology domain NUP PF06516.6 CBZ30176.1 - 0.03 13.1 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Purine nucleoside permease (NUP) GAS PF13851.1 CBZ30178.1 - 8.3e-06 25.1 0.1 8.3e-06 25.1 0.1 2.3 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF4419 PF14388.1 CBZ30178.1 - 0.062 12.5 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) HrpB7 PF09486.5 CBZ30178.1 - 0.093 12.6 14.7 0.45 10.4 3.6 2.8 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF4140 PF13600.1 CBZ30178.1 - 0.2 12.0 10.5 1 9.8 0.8 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cortex-I_coil PF09304.5 CBZ30178.1 - 0.21 11.6 5.3 0.36 10.8 0.8 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil Med9 PF07544.8 CBZ30178.1 - 0.29 10.8 2.9 0.98 9.2 0.1 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CENP-Q PF13094.1 CBZ30178.1 - 0.37 10.8 14.4 1.2 9.0 3.6 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 CBZ30178.1 - 0.47 10.0 9.6 1.2 8.6 0.6 2.4 2 0 0 2 2 2 0 IncA protein DUF4011 PF13195.1 CBZ30178.1 - 0.56 10.1 3.6 0.23 11.4 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) TBPIP PF07106.8 CBZ30178.1 - 0.76 9.3 3.6 1.4 8.4 0.4 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2746 PF10874.3 CBZ30178.1 - 1.4 9.1 4.8 0.33 11.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Troponin PF00992.15 CBZ30178.1 - 1.9 8.5 11.3 0.13 12.2 0.8 2.3 2 0 0 2 2 2 0 Troponin HalX PF08663.5 CBZ30178.1 - 2.1 8.3 7.4 17 5.4 0.8 3.5 3 0 0 3 3 3 0 HalX domain Ribosomal_S25 PF03297.10 CBZ30181.1 - 2.9e-43 146.1 3.9 3.4e-43 145.9 2.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.3 CBZ30181.1 - 0.091 11.5 0.2 0.094 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) WD40 PF00400.27 CBZ30184.1 - 3.8e-51 169.2 21.3 2.5e-08 33.4 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Ion_trans PF00520.26 CBZ30185.1 - 3.5e-98 326.7 100.7 4.1e-31 107.8 10.5 4.6 4 0 0 4 4 4 4 Ion transport protein HEAT PF02985.17 CBZ30186.1 - 1e-14 53.1 3.6 0.56 10.4 0.0 9.1 10 0 0 10 10 8 5 HEAT repeat HEAT_2 PF13646.1 CBZ30186.1 - 1.7e-14 53.8 8.1 0.00053 20.2 0.0 6.3 6 1 1 7 7 6 4 HEAT repeats Arm PF00514.18 CBZ30186.1 - 3.8e-10 39.1 3.1 0.091 12.6 0.0 6.1 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 CBZ30186.1 - 9.7e-09 35.0 0.0 1.4e-07 31.3 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 CBZ30186.1 - 3.8e-08 33.5 16.7 0.00019 21.7 0.1 7.4 6 2 4 10 10 10 3 HEAT-like repeat Adaptin_N PF01602.15 CBZ30186.1 - 1.2e-05 23.8 0.7 0.035 12.4 0.1 3.1 3 0 0 3 3 3 2 Adaptin N terminal region MMS19_C PF12460.3 CBZ30186.1 - 2.2e-05 23.4 0.0 0.019 13.7 0.0 3.4 3 2 0 3 3 3 2 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 CBZ30186.1 - 0.00024 21.4 3.1 1 9.8 0.0 4.9 4 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region Proteasom_PSMB PF10508.4 CBZ30186.1 - 0.00036 18.9 0.1 0.0022 16.3 0.0 2.2 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit CLASP_N PF12348.3 CBZ30186.1 - 0.014 14.7 2.5 0.24 10.7 0.0 3.4 3 1 1 4 4 4 0 CLASP N terminal DUF2325 PF10087.4 CBZ30186.1 - 0.014 15.1 0.1 0.048 13.5 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Telomere_reg-2 PF10193.4 CBZ30186.1 - 0.044 14.0 1.7 2.3 8.4 0.0 3.8 4 0 0 4 4 4 0 Telomere length regulation protein Amastin PF07344.6 CBZ30188.1 - 4.6e-46 156.2 12.1 5.4e-46 156.0 8.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein SNAP PF14938.1 CBZ30192.1 - 1.6e-06 27.4 15.2 2.5e-06 26.8 7.1 2.5 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.12 CBZ30192.1 - 0.00025 20.7 10.0 0.025 14.4 0.1 5.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ30192.1 - 0.00064 19.2 2.2 0.48 10.1 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ30192.1 - 0.0018 18.1 9.2 0.0061 16.4 0.4 3.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ30192.1 - 0.0019 17.8 0.1 0.11 12.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ30192.1 - 0.0027 18.3 12.5 0.96 10.2 0.4 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ30192.1 - 0.0078 15.9 1.6 0.35 10.7 0.0 4.0 3 1 2 5 5 5 1 Tetratricopeptide repeat PPR_3 PF13812.1 CBZ30192.1 - 0.04 14.2 0.1 0.73 10.2 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_14 PF13428.1 CBZ30192.1 - 0.083 13.5 6.3 6.2 7.7 0.1 4.8 5 1 1 6 6 5 0 Tetratricopeptide repeat Clathrin PF00637.15 CBZ30192.1 - 0.17 11.4 0.7 12 5.4 0.0 2.6 2 0 0 2 2 2 0 Region in Clathrin and VPS TPR_11 PF13414.1 CBZ30192.1 - 2.6 7.7 13.6 0.11 12.1 1.2 3.6 3 1 0 3 3 3 0 TPR repeat LRR_4 PF12799.2 CBZ30193.1 - 9e-17 60.2 16.3 6.5e-05 22.4 0.0 6.7 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ30193.1 - 2.3e-06 27.2 17.0 0.047 13.4 0.4 5.6 3 2 4 7 7 7 5 Leucine rich repeat MbeD_MobD PF04899.7 CBZ30193.1 - 0.48 10.3 10.1 2.3 8.1 7.0 2.1 1 0 0 1 1 1 0 MbeD/MobD like GTP_EFTU PF00009.22 CBZ30195.1 - 4.5e-43 146.8 0.2 7e-43 146.2 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CBZ30195.1 - 1.2e-29 102.3 0.6 2e-29 101.6 0.4 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CBZ30195.1 - 6.4e-14 51.5 0.0 1.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 CBZ30195.1 - 0.00024 21.0 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CBZ30195.1 - 0.00027 20.4 0.1 0.0023 17.4 0.0 2.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 CBZ30195.1 - 0.0015 17.9 0.1 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.20 CBZ30195.1 - 0.003 17.6 0.0 0.0072 16.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 FeoB_N PF02421.13 CBZ30195.1 - 0.028 13.6 0.3 0.058 12.6 0.2 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B BChl_A PF02327.12 CBZ30195.1 - 0.056 12.0 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriochlorophyll A protein Septin PF00735.13 CBZ30195.1 - 0.065 12.2 0.1 0.98 8.3 0.0 2.1 2 0 0 2 2 2 0 Septin DUF677 PF05055.7 CBZ30196.1 - 1.8e-05 23.5 2.2 2.2e-05 23.2 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DUF4618 PF15397.1 CBZ30196.1 - 0.0024 17.2 7.9 0.0026 17.1 5.5 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) YscO PF07321.7 CBZ30196.1 - 0.0028 17.4 6.8 0.0034 17.2 4.7 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO Syntaxin PF00804.20 CBZ30196.1 - 0.018 15.2 4.0 0.018 15.2 2.8 1.6 2 0 0 2 2 2 0 Syntaxin DUF904 PF06005.7 CBZ30196.1 - 0.02 15.1 8.5 0.037 14.3 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Metal_resist PF13801.1 CBZ30196.1 - 0.038 13.9 0.6 0.064 13.2 0.4 1.4 1 0 0 1 1 1 0 Heavy-metal resistance Val_tRNA-synt_C PF10458.4 CBZ30196.1 - 0.053 13.6 7.2 0.63 10.1 1.4 3.0 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm IncA PF04156.9 CBZ30196.1 - 0.059 12.9 7.6 0.076 12.6 5.2 1.3 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 CBZ30196.1 - 0.07 12.3 3.1 0.086 12.0 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FlxA PF14282.1 CBZ30196.1 - 0.096 12.6 3.1 0.16 11.9 2.1 1.4 1 0 0 1 1 1 0 FlxA-like protein NPV_P10 PF05531.7 CBZ30196.1 - 0.099 12.9 0.7 0.18 12.0 0.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 CBZ30196.1 - 0.12 12.2 1.9 0.17 11.6 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4613 PF15390.1 CBZ30196.1 - 0.15 10.2 2.4 0.15 10.2 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Prefoldin_2 PF01920.15 CBZ30196.1 - 0.15 11.8 9.1 0.21 11.3 5.8 1.5 1 1 0 1 1 1 0 Prefoldin subunit Pox_A_type_inc PF04508.7 CBZ30196.1 - 0.17 11.7 16.1 0.31 10.9 0.3 3.9 2 2 1 4 4 4 0 Viral A-type inclusion protein repeat SlyX PF04102.7 CBZ30196.1 - 0.2 12.0 5.5 3.7 7.9 0.7 2.3 1 1 1 2 2 2 0 SlyX Phage_Mu_Gam PF07352.7 CBZ30196.1 - 0.2 11.1 10.4 0.032 13.7 3.7 1.9 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein DUF724 PF05266.9 CBZ30196.1 - 0.23 11.0 11.5 0.29 10.7 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Ycf1 PF05758.7 CBZ30196.1 - 0.24 9.0 5.2 0.26 8.9 3.6 1.0 1 0 0 1 1 1 0 Ycf1 DUF1640 PF07798.6 CBZ30196.1 - 0.27 11.2 6.2 0.32 11.0 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4446 PF14584.1 CBZ30196.1 - 0.31 10.8 7.0 0.24 11.2 3.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Ax_dynein_light PF10211.4 CBZ30196.1 - 0.35 10.6 9.2 0.48 10.2 6.4 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain DUF342 PF03961.8 CBZ30196.1 - 0.39 9.0 4.0 0.4 9.0 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 CBZ30196.1 - 0.48 9.4 9.7 0.53 9.2 6.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PRP1_N PF06424.7 CBZ30196.1 - 0.91 9.8 7.5 1.1 9.5 5.2 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Tho2 PF11262.3 CBZ30196.1 - 0.93 8.4 5.1 1.2 8.1 3.5 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DJ-1_PfpI PF01965.19 CBZ30196.1 - 1 8.8 3.2 3.9 6.9 2.2 2.0 1 1 0 1 1 1 0 DJ-1/PfpI family DUF4094 PF13334.1 CBZ30196.1 - 1.5 9.2 6.3 12 6.4 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Rabaptin PF03528.10 CBZ30196.1 - 1.7 8.5 12.5 3.2 7.7 8.7 1.5 1 1 0 1 1 1 0 Rabaptin FadA PF09403.5 CBZ30196.1 - 1.9 8.4 10.6 3 7.8 7.3 1.4 1 1 0 1 1 1 0 Adhesion protein FadA V_ATPase_I PF01496.14 CBZ30196.1 - 2 6.1 5.0 2 6.1 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF883 PF05957.8 CBZ30196.1 - 2.2 8.7 7.8 0.21 12.0 2.2 1.8 2 1 0 2 2 1 0 Bacterial protein of unknown function (DUF883) TSC22 PF01166.13 CBZ30196.1 - 2.5 8.1 9.2 0.99 9.4 0.6 2.5 2 1 1 3 3 2 0 TSC-22/dip/bun family ApoL PF05461.6 CBZ30196.1 - 2.7 7.1 7.1 2.6 7.2 4.6 1.2 1 1 0 1 1 1 0 Apolipoprotein L Synaptobrevin PF00957.16 CBZ30196.1 - 2.8 7.6 5.7 1.9 8.1 2.8 1.6 2 0 0 2 2 1 0 Synaptobrevin Fib_alpha PF08702.5 CBZ30196.1 - 2.9 8.0 6.3 14 5.7 0.5 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 CBZ30196.1 - 6.2 6.3 12.5 3.9 7.0 0.9 2.8 2 1 1 3 3 3 0 Septum formation initiator IATP PF04568.7 CBZ30196.1 - 6.9 6.7 13.5 1.5 8.8 3.7 2.5 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF3373 PF11853.3 CBZ30196.1 - 9.5 4.6 7.0 14 4.0 4.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) DUF1202 PF06717.6 CBZ30198.1 - 0.074 12.3 5.6 0.11 11.6 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) DUF2910 PF11139.3 CBZ30198.1 - 0.35 9.9 1.7 0.32 10.0 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) NMO PF03060.10 CBZ30199.1 - 1.7e-67 227.9 3.7 1.1e-66 225.2 2.6 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 CBZ30199.1 - 8.3e-07 28.1 0.5 1.3e-06 27.5 0.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 CBZ30199.1 - 2.5e-06 26.6 0.1 0.0042 16.0 0.9 2.2 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 CBZ30199.1 - 4.4e-05 22.6 1.9 7.2e-05 21.9 1.3 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 CBZ30199.1 - 7.2e-05 21.8 0.1 0.00014 20.9 0.1 1.5 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 CBZ30199.1 - 0.0047 15.8 0.5 0.0078 15.1 0.3 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Peripla_BP_6 PF13458.1 CBZ30199.1 - 0.025 13.9 1.1 0.43 9.8 0.9 2.2 1 1 1 2 2 2 0 Periplasmic binding protein DUF1759 PF03564.10 CBZ30200.1 - 0.014 15.1 1.8 0.061 13.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Sec20 PF03908.8 CBZ30200.1 - 0.61 9.8 2.2 1 9.1 0.1 2.3 2 0 0 2 2 2 0 Sec20 DUF1664 PF07889.7 CBZ30200.1 - 1.6 8.5 10.9 1.5 8.6 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 CBZ30200.1 - 8.5 4.6 13.9 0.85 8.0 5.2 2.0 2 0 0 2 2 2 0 AAA domain DUF778 PF05608.7 CBZ30201.1 - 0.34 10.8 2.0 9.2 6.2 1.4 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Baculo_PEP_C PF04513.7 CBZ30201.1 - 1.9 8.2 5.5 24 4.7 1.6 3.2 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMPIT PF07851.8 CBZ30201.1 - 3.5 6.6 16.8 0.3 10.1 6.6 2.5 1 1 1 2 2 2 0 TMPIT-like protein Sec20 PF03908.8 CBZ30201.1 - 5.5 6.7 9.5 3.6 7.3 1.3 3.1 1 1 2 3 3 3 0 Sec20 AAA_13 PF13166.1 CBZ30201.1 - 6.8 5.0 18.3 4.3 5.6 11.2 1.8 2 0 0 2 2 2 0 AAA domain Filament PF00038.16 CBZ30201.1 - 7.3 5.9 46.4 0.066 12.6 11.7 4.0 2 1 1 3 3 3 0 Intermediate filament protein LRR_4 PF12799.2 CBZ30202.1 - 4e-05 23.1 1.2 3.1 7.5 0.0 5.0 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ30202.1 - 0.0068 16.1 5.2 0.052 13.3 0.0 3.8 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 CBZ30202.1 - 0.046 13.7 5.5 28 5.2 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.1 CBZ30202.1 - 2.4 8.4 8.2 89 3.6 0.1 5.6 7 0 0 7 7 7 0 Leucine Rich repeat JAB PF01398.16 CBZ30203.1 - 1.5e-29 102.0 0.0 2.9e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CBZ30203.1 - 1e-09 37.8 0.0 1.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.1 CBZ30203.1 - 4.5e-08 33.1 0.6 8e-08 32.3 0.4 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function PSD3 PF07626.6 CBZ30203.1 - 0.026 14.5 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1587) ABC_tran PF00005.22 CBZ30205.1 - 2.7e-39 134.6 0.0 6.8e-22 78.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CBZ30205.1 - 1.7e-33 116.2 20.0 9.6e-17 61.2 5.4 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 CBZ30205.1 - 8.9e-09 34.8 0.8 0.0011 18.2 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBZ30205.1 - 2.3e-07 31.1 0.0 0.077 12.9 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 CBZ30205.1 - 1.8e-05 24.8 3.3 0.19 11.6 0.5 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 CBZ30205.1 - 4e-05 23.1 0.0 0.02 14.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CBZ30205.1 - 9.5e-05 21.6 0.0 0.092 11.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CBZ30205.1 - 0.00013 21.9 0.0 0.017 15.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CBZ30205.1 - 0.00024 20.5 0.0 0.15 11.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 CBZ30205.1 - 0.0016 18.9 0.0 0.78 10.2 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA PF00004.24 CBZ30205.1 - 0.0042 17.3 0.1 1.3 9.1 0.0 3.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 CBZ30205.1 - 0.0045 16.8 0.1 1 9.1 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.1 CBZ30205.1 - 0.0058 16.7 0.1 0.3 11.2 0.0 3.2 3 1 0 3 3 2 1 AAA domain AIG1 PF04548.11 CBZ30205.1 - 0.011 14.8 0.6 1 8.3 0.1 2.4 2 0 0 2 2 2 0 AIG1 family AAA_23 PF13476.1 CBZ30205.1 - 0.016 15.5 0.1 4.1 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CBZ30205.1 - 0.021 14.5 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 CBZ30205.1 - 0.066 13.3 0.1 3.7 7.7 0.0 3.0 3 0 0 3 3 3 0 RNA helicase Adeno_IVa2 PF02456.10 CBZ30205.1 - 0.17 10.4 0.1 0.74 8.3 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF2529 PF10740.4 CBZ30206.1 - 0.00028 20.3 0.4 1.3 8.3 0.0 3.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2529) Repressor_Mnt PF11423.3 CBZ30206.1 - 0.0005 19.3 25.3 0.13 11.5 1.0 5.6 5 0 0 5 5 5 3 Regulatory protein Mnt HHH_2 PF12826.2 CBZ30206.1 - 0.0006 19.6 5.7 1.6 8.6 0.0 4.5 4 0 0 4 4 4 2 Helix-hairpin-helix motif GAS PF13851.1 CBZ30206.1 - 0.0026 17.0 6.1 0.0026 17.0 4.2 6.3 6 1 1 7 7 7 4 Growth-arrest specific micro-tubule binding HHH_3 PF12836.2 CBZ30206.1 - 0.0043 16.9 0.1 7 6.6 0.0 3.0 3 0 0 3 3 3 2 Helix-hairpin-helix motif Sec8_exocyst PF04048.9 CBZ30206.1 - 0.0086 15.7 1.1 0.073 12.7 0.1 3.1 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain Prominin PF05478.6 CBZ30206.1 - 0.022 12.3 1.6 0.05 11.1 1.1 1.6 1 0 0 1 1 1 0 Prominin DUF2973 PF11189.3 CBZ30206.1 - 0.03 14.0 1.5 1.7 8.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2973) TLE_N PF03920.10 CBZ30206.1 - 0.13 12.1 7.6 23 4.7 0.2 4.0 3 0 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain NUDE_C PF04880.8 CBZ30206.1 - 0.16 12.3 37.6 5.8 7.2 0.1 7.9 7 1 0 8 8 8 0 NUDE protein, C-terminal conserved region Tmemb_cc2 PF10267.4 CBZ30206.1 - 0.23 10.0 24.4 5 5.5 5.4 5.5 1 1 5 6 6 6 0 Predicted transmembrane and coiled-coil 2 protein FlaC_arch PF05377.6 CBZ30206.1 - 2 8.3 12.7 2.7 7.9 0.1 5.4 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) ERM PF00769.14 CBZ30207.1 - 1.7e-19 70.3 370.7 0.0028 17.2 21.0 13.8 4 2 12 16 16 16 12 Ezrin/radixin/moesin family Cast PF10174.4 CBZ30207.1 - 5e-17 61.2 300.9 6.3e-09 34.4 70.1 8.5 3 2 4 7 7 7 5 RIM-binding protein of the cytomatrix active zone CENP-F_leu_zip PF10473.4 CBZ30207.1 - 0.072 12.9 323.8 0.13 12.1 11.4 15.8 5 2 12 17 17 17 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 CBZ30207.1 - 0.13 12.0 194.4 4.5 7.0 1.5 23.0 22 0 0 22 22 22 0 Homeobox associated leucine zipper DUF2039 PF10217.4 CBZ30208.1 - 5.7e-27 93.5 22.2 8.8e-27 92.9 15.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Astro_capsid PF03115.9 CBZ30208.1 - 0.09 11.0 2.5 0.096 10.9 1.8 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Transmemb_17 PF09799.4 CBZ30209.1 - 3.2e-29 101.4 11.0 4.3e-29 101.0 7.6 1.2 1 0 0 1 1 1 1 Predicted membrane protein NVEALA PF14055.1 CBZ30209.1 - 0.057 13.1 1.0 0.16 11.7 0.7 1.7 1 0 0 1 1 1 0 NVEALA protein Sod_Fe_C PF02777.13 CBZ30211.1 - 0.003 17.3 0.0 0.0087 15.8 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Tcp10_C PF07202.8 CBZ30211.1 - 0.0057 16.2 0.1 0.0092 15.5 0.1 1.2 1 0 0 1 1 1 1 T-complex protein 10 C-terminus SpoIIE PF07228.7 CBZ30212.1 - 1.1e-08 35.0 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CBZ30212.1 - 0.0017 17.8 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CBZ30212.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C CBF PF03914.12 CBZ30213.1 - 1.2e-36 125.6 0.2 1.8e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 CBF/Mak21 family NAD_binding_10 PF13460.1 CBZ30215.1 - 9.8e-05 22.4 0.1 0.00023 21.2 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CBZ30215.1 - 0.00062 19.0 0.2 0.0012 18.1 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.15 CBZ30215.1 - 0.0027 17.8 0.1 0.0043 17.1 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CBZ30215.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 CBZ30215.1 - 0.022 13.7 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.20 CBZ30215.1 - 0.052 13.4 0.1 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 CBZ30215.1 - 0.14 10.7 0.0 0.3 9.7 0.0 1.4 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family BTV_NS2 PF04514.7 CBZ30216.1 - 0.19 10.5 6.5 0.24 10.2 4.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Metallophos PF00149.23 CBZ30217.1 - 1.1e-36 126.1 0.2 1.5e-36 125.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 CBZ30218.1 - 2.8e-37 128.0 0.2 3.4e-37 127.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 CBZ30219.1 - 1.2e-36 125.9 0.2 1.7e-36 125.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 CBZ30220.1 - 5.2e-36 123.9 0.4 7e-36 123.5 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pcc1 PF09341.5 CBZ30221.1 - 7.2e-17 61.1 0.2 9.6e-17 60.7 0.1 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 EF1_GNE PF00736.14 CBZ30222.1 - 9.3e-30 102.1 2.2 1.5e-29 101.5 1.5 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DUF3275 PF11679.3 CBZ30222.1 - 0.71 9.4 3.3 1.2 8.6 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) MSP1_C PF07462.6 CBZ30222.1 - 1.1 7.6 6.2 1.4 7.2 4.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus GST_C_2 PF13410.1 CBZ30223.1 - 0.009 15.8 0.1 0.016 15.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AsnC_trans_reg PF01037.16 CBZ30223.1 - 0.091 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AsnC family CRISPR_Cse1 PF09481.5 CBZ30223.1 - 0.091 11.4 0.3 0.11 11.2 0.2 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) ParA PF10609.4 CBZ30223.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 ParA/MinD ATPase like EF1_GNE PF00736.14 CBZ30224.1 - 1.6e-29 101.4 2.2 2.6e-29 100.7 1.5 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain MSP1_C PF07462.6 CBZ30224.1 - 2.2 6.5 6.5 3 6.1 4.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Metallophos PF00149.23 CBZ30225.1 - 7.2e-35 120.1 0.0 8.6e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CBZ30225.1 - 0.028 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L13 PF00572.13 CBZ30226.1 - 3.8e-22 78.7 0.7 5.3e-22 78.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 alpha-hel2 PF14456.1 CBZ30226.1 - 0.11 11.2 1.7 0.17 10.6 1.1 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 RNA_pol_Rpb6 PF01192.17 CBZ30229.1 - 5.5e-19 67.6 0.5 8.8e-19 66.9 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 UQ_con PF00179.21 CBZ30230.1 - 1.7e-19 69.6 0.0 2.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBZ30230.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain DNA_pol_viral_C PF00336.13 CBZ30233.1 - 0.14 11.3 0.1 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Pkinase PF00069.20 CBZ30234.1 - 1.2e-37 129.4 0.0 1e-28 100.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30234.1 - 1.1e-19 70.6 0.0 1.6e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CBZ30234.1 - 0.098 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ30234.1 - 0.18 11.5 0.0 0.18 11.5 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBZ30234.1 - 0.65 8.7 0.1 0.98 8.1 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Rhodanese PF00581.15 CBZ30235.1 - 3.6e-10 40.1 0.0 0.0013 19.0 0.0 3.1 2 1 0 2 2 2 2 Rhodanese-like domain Y_phosphatase3 PF13350.1 CBZ30235.1 - 0.068 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family PAN_4 PF14295.1 CBZ30235.1 - 0.43 10.3 2.7 0.36 10.5 0.4 2.0 2 0 0 2 2 2 0 PAN domain Amastin PF07344.6 CBZ30236.1 - 1.2e-55 187.3 10.3 1.4e-55 187.1 7.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_3 PF06653.6 CBZ30236.1 - 0.038 13.6 9.2 0.34 10.6 2.4 3.0 2 1 1 3 3 3 0 Tight junction protein, Claudin-like Claudin_2 PF13903.1 CBZ30236.1 - 0.062 12.9 15.0 0.11 12.1 9.7 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4293 PF14126.1 CBZ30236.1 - 0.11 12.4 4.3 0.33 10.8 3.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Amastin PF07344.6 CBZ30237.1 - 2.3e-54 183.2 12.3 2.7e-54 183.0 8.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4293 PF14126.1 CBZ30237.1 - 0.0077 16.1 3.6 0.017 15.0 2.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4293) UPF0233 PF06781.7 CBZ30237.1 - 0.012 15.2 3.8 0.044 13.4 2.6 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Claudin_2 PF13903.1 CBZ30237.1 - 3.5 7.2 17.0 0.13 11.9 6.4 2.0 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBZ30238.1 - 7.3e-49 165.3 9.1 8.8e-49 165.0 6.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ30238.1 - 2.9 7.5 19.8 7.7 6.1 11.3 2.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBZ30239.1 - 6e-38 129.9 13.5 7.1e-38 129.6 9.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ30239.1 - 0.72 9.5 15.3 0.99 9.0 10.1 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ABC_membrane PF00664.18 CBZ30240.1 - 5.5e-116 386.7 18.9 5.3e-63 213.0 6.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CBZ30240.1 - 5e-68 227.6 0.0 9.1e-33 113.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CBZ30240.1 - 2.9e-13 49.5 0.6 4.3e-06 26.1 0.0 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CBZ30240.1 - 1.4e-07 31.8 0.0 0.088 12.7 0.0 3.7 3 1 1 4 4 4 2 AAA domain DUF258 PF03193.11 CBZ30240.1 - 2.9e-07 29.7 0.0 0.017 14.3 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBZ30240.1 - 1.1e-05 26.2 0.0 0.0081 16.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 CBZ30240.1 - 2e-05 23.3 0.0 0.03 12.9 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA PF00004.24 CBZ30240.1 - 3.3e-05 24.0 0.0 1.2 9.3 0.1 3.6 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ30240.1 - 4.3e-05 23.6 2.4 0.078 13.1 0.0 4.0 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CBZ30240.1 - 6e-05 22.4 1.1 0.33 10.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 CBZ30240.1 - 8.9e-05 22.0 0.0 0.099 12.1 0.0 2.7 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.1 CBZ30240.1 - 0.00014 21.8 1.4 0.12 12.3 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CBZ30240.1 - 0.00069 19.3 0.0 0.02 14.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 CBZ30240.1 - 0.0015 18.3 4.7 2.7 7.9 0.1 4.4 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 CBZ30240.1 - 0.0056 16.1 0.0 3.9 6.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF815 PF05673.8 CBZ30240.1 - 0.013 14.4 0.1 0.97 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Miro PF08477.8 CBZ30240.1 - 0.017 15.6 0.1 3.9 7.9 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 CBZ30240.1 - 0.018 15.3 0.3 0.49 10.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBZ30240.1 - 0.02 15.0 0.3 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 CBZ30240.1 - 0.033 13.7 0.1 12 5.4 0.0 3.2 3 1 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 CBZ30240.1 - 0.044 12.8 0.0 6.5 5.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.13 CBZ30240.1 - 0.065 12.7 0.5 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.15 CBZ30240.1 - 0.089 11.4 0.0 3.2 6.3 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.1 CBZ30240.1 - 0.092 12.7 0.0 13 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 CBZ30240.1 - 0.094 12.6 0.2 3.8 7.5 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase DUF2852 PF11014.3 CBZ30240.1 - 0.1 12.5 1.4 9.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) AAA_18 PF13238.1 CBZ30240.1 - 0.17 12.1 0.0 4 7.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain Myosin_head PF00063.16 CBZ30241.1 - 3.9e-197 656.4 0.0 2.5e-196 653.7 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CBZ30241.1 - 2.1e-09 36.9 0.0 0.0042 16.4 0.0 3.4 3 1 0 3 3 3 2 Myosin tail FYVE PF01363.16 CBZ30241.1 - 2.7e-05 23.9 7.2 6.6e-05 22.7 5.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger AAA_22 PF13401.1 CBZ30241.1 - 0.02 15.0 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CBZ30241.1 - 0.022 15.5 0.4 0.52 11.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.4 CBZ30241.1 - 0.052 12.5 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CBZ30241.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter N2227 PF07942.7 CBZ30243.1 - 7.5e-94 313.6 0.0 9.3e-94 313.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein EF-hand_8 PF13833.1 CBZ30244.1 - 1.6e-09 37.1 0.1 2.8e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 CBZ30244.1 - 3.2e-09 36.7 0.0 5.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ30244.1 - 8.6e-07 27.8 0.0 0.00059 18.9 0.1 2.8 2 1 1 3 3 3 2 EF hand EF-hand_6 PF13405.1 CBZ30244.1 - 1.1e-05 24.9 0.1 0.026 14.3 0.1 3.2 1 1 2 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CBZ30244.1 - 2.3e-05 23.5 1.6 6.3e-05 22.1 0.2 2.4 2 0 0 2 2 2 1 EF hand FG-GAP PF01839.18 CBZ30244.1 - 0.053 13.2 0.4 0.17 11.6 0.3 1.9 1 0 0 1 1 1 0 FG-GAP repeat UPRTase PF14681.1 CBZ30245.1 - 4e-70 235.2 0.0 4.9e-70 234.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CBZ30245.1 - 1.4e-06 27.9 0.0 2.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TPR_11 PF13414.1 CBZ30246.1 - 2.4e-19 68.7 2.0 2.9e-06 26.8 0.0 3.6 2 1 1 3 3 3 3 TPR repeat SET PF00856.23 CBZ30246.1 - 1.2e-13 51.6 0.0 3.1e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 SET domain TPR_2 PF07719.12 CBZ30246.1 - 3.7e-08 32.6 9.8 0.00052 19.7 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ30246.1 - 1.8e-06 27.8 4.7 0.0074 16.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ30246.1 - 0.0035 17.8 4.9 0.087 13.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ30246.1 - 0.0058 16.2 13.5 0.0072 15.8 0.2 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ30246.1 - 0.045 13.5 2.6 0.11 12.3 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ30246.1 - 0.062 13.1 2.1 0.93 9.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ30246.1 - 0.068 13.1 1.2 1.1 9.2 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ30246.1 - 0.14 12.8 5.2 11 6.7 0.5 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M41 PF01434.13 CBZ30247.1 - 1.4e-44 152.1 0.0 2e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CBZ30247.1 - 2.1e-39 134.7 0.0 3.7e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBZ30247.1 - 9.1e-05 21.9 0.5 0.16 11.3 0.0 2.7 2 1 1 3 3 3 2 AAA domain AAA_2 PF07724.9 CBZ30247.1 - 0.00018 21.4 0.0 0.00041 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CBZ30247.1 - 0.00046 19.8 0.4 0.0031 17.2 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CBZ30247.1 - 0.00049 20.2 0.0 0.01 15.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ30247.1 - 0.0005 19.1 0.0 0.0011 18.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CBZ30247.1 - 0.00052 20.8 0.0 0.0019 19.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ30247.1 - 0.00075 19.5 0.5 0.1 12.5 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 CBZ30247.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CBZ30247.1 - 0.0022 16.7 0.0 0.0036 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 CBZ30247.1 - 0.0067 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 CBZ30247.1 - 0.0097 15.6 1.3 0.11 12.1 0.2 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CBZ30247.1 - 0.037 14.3 0.0 0.58 10.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.16 CBZ30247.1 - 0.046 12.8 0.1 0.13 11.4 0.1 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Lipase_3 PF01764.20 CBZ30248.1 - 2.4e-07 30.4 0.0 5.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 CBZ30248.1 - 7.1e-05 22.5 0.1 0.00023 20.9 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ30248.1 - 0.00012 22.0 0.3 0.00043 20.2 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 CBZ30248.1 - 0.00046 19.6 0.2 0.0023 17.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 CBZ30248.1 - 0.11 12.7 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 CBZ30248.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Acyltransferase PF01553.16 CBZ30249.1 - 1.5e-18 66.5 0.0 3.9e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase DUF2363 PF10155.4 CBZ30250.1 - 0.18 11.7 0.1 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) SBDS_C PF09377.5 CBZ30251.1 - 5.4e-32 110.1 0.0 9.2e-32 109.3 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 CBZ30251.1 - 3.4e-24 84.4 0.6 6e-24 83.6 0.4 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF1042 PF06294.6 CBZ30252.1 - 7.9e-33 113.2 0.0 1.5e-32 112.3 0.0 1.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1042) CAMSAP_CH PF11971.3 CBZ30252.1 - 4.3e-24 83.9 0.0 7.4e-24 83.2 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.26 CBZ30252.1 - 4.6e-06 26.6 0.0 8.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain TMF_DNA_bd PF12329.3 CBZ30252.1 - 0.074 12.8 1.8 0.29 10.9 1.3 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding T2SK PF03934.8 CBZ30252.1 - 0.11 11.6 0.2 4.4 6.3 0.0 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein K SlyX PF04102.7 CBZ30252.1 - 0.24 11.7 1.8 0.39 11.1 0.3 2.1 2 0 0 2 2 2 0 SlyX Dus PF01207.12 CBZ30254.1 - 3.5e-53 180.4 0.0 2.6e-51 174.2 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 CBZ30254.1 - 0.011 14.9 0.0 0.027 13.7 0.0 1.5 2 0 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.9 CBZ30254.1 - 0.012 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG BMC PF00936.14 CBZ30254.1 - 0.12 12.0 1.7 0.36 10.5 0.2 2.3 2 0 0 2 2 2 0 BMC domain DUF167 PF02594.11 CBZ30256.1 - 1.7e-11 43.8 0.0 2.2e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 FlaC_arch PF05377.6 CBZ30258.1 - 2.8 7.9 24.1 1.8 8.5 0.6 5.9 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) HA2 PF04408.18 CBZ30261.1 - 3.9e-15 55.7 0.0 2.6e-14 53.0 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.24 CBZ30261.1 - 2e-10 40.4 0.1 4.6e-10 39.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ30261.1 - 4.9e-10 39.1 0.1 5.7e-09 35.7 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain dsrm PF00035.20 CBZ30261.1 - 6.1e-06 26.7 0.2 0.023 15.2 0.1 3.7 3 0 0 3 3 3 1 Double-stranded RNA binding motif AAA_22 PF13401.1 CBZ30261.1 - 0.00069 19.7 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 CBZ30261.1 - 0.008 15.9 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold T2SE PF00437.15 CBZ30261.1 - 0.014 14.2 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.10 CBZ30261.1 - 0.085 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PhoH PF02562.11 CBZ30261.1 - 0.13 11.4 0.1 5.4 6.2 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.1 CBZ30261.1 - 0.35 10.7 0.0 2.8 7.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF2448 PF10476.4 CBZ30262.1 - 0.025 14.0 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) F-box PF00646.28 CBZ30263.1 - 0.024 14.2 0.4 0.049 13.2 0.3 1.5 1 0 0 1 1 1 0 F-box domain Exo_endo_phos PF03372.18 CBZ30264.1 - 9.3e-16 58.5 0.2 2.2e-15 57.2 0.1 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HALZ PF02183.13 CBZ30265.1 - 0.012 15.2 0.7 0.012 15.2 0.5 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper Shugoshin_N PF07558.6 CBZ30265.1 - 0.069 12.8 5.0 0.15 11.7 0.9 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Vps51 PF08700.6 CBZ30265.1 - 0.16 11.8 5.3 0.25 11.2 1.9 2.4 2 0 0 2 2 2 0 Vps51/Vps67 TSC22 PF01166.13 CBZ30265.1 - 0.2 11.6 3.7 0.8 9.7 0.3 3.1 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF972 PF06156.8 CBZ30265.1 - 0.28 11.5 3.8 0.36 11.1 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 CBZ30265.1 - 1.5 8.3 8.1 5.9 6.4 1.8 2.7 2 1 0 2 2 2 0 Septum formation initiator DNA_pol_A_exo1 PF01612.15 CBZ30266.1 - 6.4e-14 51.8 0.1 3.1e-13 49.6 0.0 2.1 2 1 0 2 2 2 1 3'-5' exonuclease zf-CCCH PF00642.19 CBZ30266.1 - 0.00091 18.8 0.2 0.0019 17.8 0.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WH2 PF02205.15 CBZ30266.1 - 0.0048 16.4 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 WH2 motif NIF PF03031.13 CBZ30268.1 - 1.4e-31 109.3 0.4 1e-30 106.4 0.1 2.3 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase DNA_pol_A PF00476.15 CBZ30269.1 - 2.4e-69 233.8 0.0 6.3e-63 212.6 0.0 2.6 2 1 0 2 2 2 2 DNA polymerase family A DUF3595 PF12166.3 CBZ30270.1 - 1.2e-118 396.6 0.0 1.6e-118 396.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3595) Fae PF08714.6 CBZ30270.1 - 0.12 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Formaldehyde-activating enzyme (Fae) LRR_6 PF13516.1 CBZ30272.1 - 0.0022 17.8 1.9 17 5.8 0.0 5.6 6 0 0 6 6 6 1 Leucine Rich repeat OsmC PF02566.14 CBZ30273.1 - 1.7e-06 28.1 0.4 3.2e-06 27.2 0.3 1.5 1 0 0 1 1 1 1 OsmC-like protein IATP PF04568.7 CBZ30273.1 - 0.11 12.5 10.1 0.57 10.2 0.1 3.0 3 1 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP FRG PF08867.6 CBZ30273.1 - 0.13 12.7 1.0 0.61 10.6 0.4 2.0 2 0 0 2 2 2 0 FRG domain BRF1 PF07741.8 CBZ30273.1 - 0.36 11.0 3.1 0.88 9.8 2.1 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain BCS1_N PF08740.6 CBZ30276.1 - 8.4e-35 120.0 1.6 1.2e-34 119.5 1.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CBZ30276.1 - 4.3e-20 72.2 0.0 1.2e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CBZ30276.1 - 3.9e-05 23.7 0.1 9.8e-05 22.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CBZ30276.1 - 0.00031 20.5 0.5 0.0036 17.0 0.3 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CBZ30276.1 - 0.00052 19.1 0.0 0.00087 18.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBZ30276.1 - 0.00058 20.0 0.1 0.014 15.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CBZ30276.1 - 0.00061 20.0 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 CBZ30276.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ30276.1 - 0.0015 19.3 0.0 0.003 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CBZ30276.1 - 0.002 17.0 0.0 0.0045 15.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_11 PF13086.1 CBZ30276.1 - 0.0022 17.5 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ30276.1 - 0.0052 16.5 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Arch_ATPase PF01637.13 CBZ30276.1 - 0.0059 16.3 0.0 1.2 8.8 0.0 2.4 1 1 1 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 CBZ30276.1 - 0.0082 16.2 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 CBZ30276.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 CBZ30276.1 - 0.019 13.6 0.0 0.036 12.7 0.0 1.4 1 1 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 CBZ30276.1 - 0.027 13.8 0.0 0.091 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CBZ30276.1 - 0.027 14.1 0.0 0.11 12.1 0.0 2.1 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 CBZ30276.1 - 0.035 14.3 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 CBZ30276.1 - 0.036 12.7 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_28 PF13521.1 CBZ30276.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CBZ30276.1 - 0.054 12.5 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.13 CBZ30276.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 CBZ30276.1 - 0.094 12.1 0.1 0.26 10.6 0.1 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein Miro PF08477.8 CBZ30276.1 - 0.14 12.6 0.0 0.56 10.7 0.0 2.1 2 0 0 2 2 1 0 Miro-like protein IncA PF04156.9 CBZ30278.1 - 0.011 15.3 0.8 0.028 14.0 0.5 1.7 1 0 0 1 1 1 0 IncA protein COG5 PF10392.4 CBZ30278.1 - 0.013 15.4 0.2 0.035 14.0 0.2 1.7 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF3166 PF11365.3 CBZ30278.1 - 0.22 12.0 4.9 0.27 11.7 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3166) APG6 PF04111.7 CBZ30280.1 - 0.26 10.2 9.7 0.39 9.7 6.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 COG2 PF06148.6 CBZ30280.1 - 1.6 8.5 5.1 3 7.7 1.8 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Mnd1 PF03962.10 CBZ30280.1 - 1.8 8.2 8.1 2.9 7.5 5.6 1.4 1 0 0 1 1 1 0 Mnd1 family DUF1664 PF07889.7 CBZ30280.1 - 9.9 5.9 7.1 12 5.7 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Chorein_N PF12624.2 CBZ30282.1 - 1.7e-29 101.7 0.0 3.6e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF1162 PF06650.7 CBZ30282.1 - 5.1e-16 58.6 0.0 8.7e-15 54.6 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1162) TSSC4 PF15264.1 CBZ30282.1 - 0.084 13.3 0.2 0.49 10.8 0.1 2.2 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 2-Hacid_dh_C PF02826.14 CBZ30283.1 - 3.2e-40 137.1 0.0 4.2e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CBZ30283.1 - 1.3e-05 24.5 0.1 3.9e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 CBZ30283.1 - 1.5e-05 24.9 0.2 2.8e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 CBZ30283.1 - 1.6e-05 25.0 0.1 2.8e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding AdoHcyase_NAD PF00670.16 CBZ30283.1 - 4.3e-05 23.4 0.9 4.3e-05 23.4 0.6 2.5 3 1 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 CBZ30283.1 - 0.00079 19.8 0.2 0.0033 17.8 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh PF00389.25 CBZ30283.1 - 0.047 13.1 0.0 0.074 12.5 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.1 CBZ30283.1 - 0.11 12.8 0.2 0.26 11.5 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 CBZ30283.1 - 0.12 12.7 0.2 0.29 11.5 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 CBZ30284.1 - 1.4e-33 115.5 0.0 1.7e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CBZ30284.1 - 0.061 13.1 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 CBZ30285.1 - 5.6e-45 152.6 0.0 7.1e-45 152.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CBZ30285.1 - 1.7e-05 24.2 0.1 5e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 CBZ30285.1 - 1.9e-05 24.6 0.2 3.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 CBZ30285.1 - 1.9e-05 24.7 0.1 3.5e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding AdoHcyase_NAD PF00670.16 CBZ30285.1 - 5.5e-05 23.0 0.9 5.5e-05 23.0 0.6 2.3 3 1 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain F420_oxidored PF03807.12 CBZ30285.1 - 0.00097 19.5 0.2 0.004 17.5 0.1 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh PF00389.25 CBZ30285.1 - 0.031 13.7 0.0 0.057 12.8 0.0 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF1143 PF06608.6 CBZ30286.1 - 0.011 15.6 0.0 0.032 14.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1143) PTEN_C2 PF10409.4 CBZ30287.1 - 7.5e-11 41.8 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 CBZ30287.1 - 5.2e-09 35.7 0.2 9.9e-09 34.8 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ30287.1 - 2.9e-05 23.5 0.1 6.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBZ30287.1 - 0.0019 18.4 0.5 0.0043 17.3 0.4 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBZ30287.1 - 0.0029 17.6 0.1 0.0079 16.2 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF3353 PF11833.3 CBZ30287.1 - 0.057 12.8 0.6 0.095 12.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) R3H-assoc PF13902.1 CBZ30289.1 - 1.5e-18 67.0 0.0 2.7e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 CBZ30289.1 - 0.0012 18.4 0.1 0.0057 16.3 0.0 2.1 2 0 0 2 2 2 1 R3H domain PPR_2 PF13041.1 CBZ30290.1 - 0.013 15.5 0.0 9.3 6.3 0.0 3.6 4 0 0 4 4 4 0 PPR repeat family HTH_Tnp_Mu_1 PF02316.11 CBZ30290.1 - 0.061 13.0 0.2 0.17 11.5 0.2 1.7 1 0 0 1 1 1 0 Mu DNA-binding domain PPR PF01535.15 CBZ30290.1 - 0.081 12.9 0.0 11 6.2 0.0 2.9 2 0 0 2 2 2 0 PPR repeat EAP30 PF04157.11 CBZ30291.1 - 9.5e-88 293.0 0.3 1.2e-87 292.8 0.2 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family DUF4189 PF13827.1 CBZ30291.1 - 3.7 7.8 5.9 3.9 7.7 1.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4189) YueH PF14166.1 CBZ30293.1 - 0.092 12.5 1.5 4 7.2 0.0 3.0 3 1 1 4 4 4 0 YueH-like protein DUF3808 PF10300.4 CBZ30294.1 - 1.2e-42 146.0 0.7 2.1e-42 145.2 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF4094 PF13334.1 CBZ30295.1 - 0.04 14.2 0.8 0.21 11.9 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) MerR-DNA-bind PF09278.6 CBZ30295.1 - 1.8 8.9 5.6 0.96 9.8 1.5 2.3 3 0 0 3 3 3 0 MerR, DNA binding p25-alpha PF05517.7 CBZ30296.1 - 6e-41 140.2 3.6 6.6e-41 140.1 2.5 1.0 1 0 0 1 1 1 1 p25-alpha SCP-1 PF05483.7 CBZ30296.1 - 0.045 11.5 0.1 0.053 11.3 0.1 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Kinesin PF00225.18 CBZ30297.1 - 1.9e-88 296.3 0.0 2.7e-88 295.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain TrwB_AAD_bind PF10412.4 CBZ30297.1 - 0.03 12.9 1.6 0.032 12.8 0.0 1.7 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Bac_DnaA PF00308.13 CBZ30297.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Helicase_C PF00271.26 CBZ30298.1 - 1.7e-05 24.6 0.0 4.8e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ30298.1 - 9e-05 22.0 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.1 CBZ30298.1 - 0.014 15.0 1.6 0.035 13.8 0.1 2.4 3 0 0 3 3 3 0 Part of AAA domain ResIII PF04851.10 CBZ30298.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UQ_con PF00179.21 CBZ30299.1 - 1.6e-22 79.4 0.0 1.9e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CBZ30299.1 - 0.0071 16.0 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B Amastin PF07344.6 CBZ30300.1 - 1.4e-46 157.9 10.6 1.6e-46 157.7 7.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ30300.1 - 2.5e-05 24.0 8.3 2.5e-05 24.0 5.8 1.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2417 PF10329.4 CBZ30300.1 - 8.6 5.6 8.3 4 6.7 0.1 2.3 1 1 0 2 2 2 0 Region of unknown function (DUF2417) Amastin PF07344.6 CBZ30302.1 - 1.8e-49 167.3 11.3 2.2e-49 167.0 7.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4389 PF14333.1 CBZ30302.1 - 0.34 10.6 5.9 0.9 9.2 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4389) DUF1218 PF06749.7 CBZ30302.1 - 1.1 9.7 13.8 2.2 8.7 1.3 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1218) DUF4064 PF13273.1 CBZ30302.1 - 1.5 8.9 9.3 12 6.0 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Zeta_toxin PF06414.7 CBZ30303.1 - 6.7e-11 41.6 0.0 1.9e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 CBZ30303.1 - 0.011 15.6 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thioredoxin PF00085.15 CBZ30303.1 - 0.12 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin AAA_18 PF13238.1 CBZ30303.1 - 0.19 12.0 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_C15 PF01470.12 CBZ30304.1 - 1.1e-10 41.6 0.2 6e-05 22.9 0.1 2.3 2 0 0 2 2 2 2 Pyroglutamyl peptidase RCC1 PF00415.13 CBZ30306.1 - 1.1e-24 86.3 2.3 2.6e-08 33.9 0.0 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CBZ30306.1 - 6.5e-18 63.8 10.2 1.5e-10 40.3 1.3 5.6 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat TPR_12 PF13424.1 CBZ30307.1 - 7.3e-06 25.8 0.1 7.3e-06 25.8 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat IQ PF00612.22 CBZ30307.1 - 0.00028 20.2 38.7 0.011 15.3 0.8 7.2 6 0 0 6 6 6 4 IQ calmodulin-binding motif TPR_11 PF13414.1 CBZ30307.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.9 3 0 0 3 3 3 0 TPR repeat DEAD PF00270.24 CBZ30309.1 - 2e-42 144.5 0.0 4.1e-42 143.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ30309.1 - 3.7e-20 71.5 0.0 8.1e-20 70.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CBZ30309.1 - 5.9e-09 35.6 4.1 1.3e-08 34.4 2.8 1.6 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 CBZ30309.1 - 0.018 14.8 0.0 0.057 13.2 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Stk19 PF10494.4 CBZ30310.1 - 0.087 12.2 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Serine-threonine protein kinase 19 FtsX PF02687.16 CBZ30311.1 - 4.9e-21 74.7 37.2 2.2e-15 56.5 8.9 5.5 5 1 2 7 7 7 2 FtsX-like permease family OSTbeta PF15048.1 CBZ30311.1 - 0.7 9.9 2.6 0.7 9.9 0.0 2.3 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Pkinase PF00069.20 CBZ30313.1 - 3.3e-55 187.0 0.0 3.9e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30313.1 - 3.2e-31 108.3 0.0 4.1e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ30313.1 - 0.00053 19.0 0.0 0.00076 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PLDc_2 PF13091.1 CBZ30315.1 - 3.3e-25 88.2 0.0 5e-18 65.0 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CBZ30315.1 - 1.3e-07 31.1 3.2 0.012 15.4 0.7 2.4 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF1614 PF07758.6 CBZ30316.1 - 0.033 13.9 0.3 0.046 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1614) Tim17 PF02466.14 CBZ30316.1 - 0.27 11.2 6.0 0.68 9.9 4.2 1.6 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family ubiquitin PF00240.18 CBZ30317.1 - 1.3e-16 59.7 0.0 1.5e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CBZ30317.1 - 1.2e-07 31.2 0.0 1.3e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CBZ30317.1 - 0.001 18.9 0.1 0.002 17.9 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CBZ30317.1 - 0.026 14.7 0.0 0.06 13.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain DoxX PF07681.7 CBZ30318.1 - 0.00045 20.5 7.3 0.00045 20.5 5.1 1.6 2 0 0 2 2 2 1 DoxX DUF4239 PF14023.1 CBZ30318.1 - 0.0048 16.2 0.6 0.0084 15.4 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) PRA1 PF03208.14 CBZ30318.1 - 0.04 13.2 2.6 0.068 12.5 1.8 1.5 1 0 0 1 1 1 0 PRA1 family protein SURF4 PF02077.10 CBZ30318.1 - 0.47 9.7 3.7 1.5 8.1 0.0 2.1 1 1 0 2 2 2 0 SURF4 family SIR2 PF02146.12 CBZ30319.1 - 3.1e-45 154.0 0.0 3.8e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Pkinase PF00069.20 CBZ30320.1 - 1e-42 146.1 0.0 1.7e-41 142.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30320.1 - 1.4e-23 83.2 0.0 1.3e-20 73.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ30320.1 - 0.015 14.2 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 CBZ30320.1 - 0.1 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SecA_PP_bind PF01043.15 CBZ30320.1 - 0.17 12.2 0.1 23 5.3 0.0 2.8 3 0 0 3 3 3 0 SecA preprotein cross-linking domain OGG_N PF07934.7 CBZ30322.1 - 2.6e-29 101.5 0.0 4.3e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CBZ30322.1 - 1.5e-08 34.8 0.0 9.8e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CBZ30322.1 - 0.00029 20.3 0.0 0.0029 17.2 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif HEAT_2 PF13646.1 CBZ30323.1 - 0.016 15.4 0.2 0.016 15.4 0.1 3.9 4 0 0 4 4 4 0 HEAT repeats Pkinase PF00069.20 CBZ30324.1 - 3e-48 164.2 0.0 4.3e-26 91.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30324.1 - 4.6e-30 104.5 0.0 4.7e-17 61.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase DSPc PF00782.15 CBZ30324.1 - 6.8e-27 93.6 0.0 1.4e-26 92.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.2 CBZ30324.1 - 2e-11 43.2 16.3 8e-07 28.5 2.3 3.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ30324.1 - 4.7e-08 31.9 10.0 0.23 11.6 0.1 6.3 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_8 PF13855.1 CBZ30324.1 - 2.8e-07 30.1 10.8 1.7e-06 27.6 3.6 3.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 CBZ30324.1 - 1e-05 24.9 3.5 4.1 8.0 0.0 5.5 4 0 0 4 4 4 2 Leucine rich repeat Y_phosphatase PF00102.22 CBZ30324.1 - 0.00051 19.4 0.0 0.00091 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Thioredoxin PF00085.15 CBZ30325.1 - 5.4e-27 93.4 0.0 4e-26 90.7 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 CBZ30325.1 - 6.5e-10 39.1 0.1 1.5e-08 34.8 0.0 3.1 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ30325.1 - 9e-08 32.1 0.0 2.4e-06 27.5 0.0 3.1 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_6 PF13848.1 CBZ30325.1 - 5.4e-05 23.0 0.0 0.00089 19.1 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.5 CBZ30325.1 - 0.00018 21.0 0.1 0.0018 17.8 0.0 2.5 2 1 1 3 3 3 1 Redoxin AhpC-TSA PF00578.16 CBZ30325.1 - 0.0006 19.4 0.0 0.0049 16.5 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 CBZ30325.1 - 0.0013 18.6 0.0 0.004 17.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 CBZ30325.1 - 0.003 17.1 0.0 0.0068 15.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 CBZ30325.1 - 0.012 15.5 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin DUF2644 PF10841.3 CBZ30325.1 - 0.048 13.7 0.1 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) TraF PF13728.1 CBZ30325.1 - 0.095 12.1 0.0 0.7 9.3 0.0 2.3 3 0 0 3 3 3 0 F plasmid transfer operon protein Exo_endo_phos PF03372.18 CBZ30327.1 - 9.3e-13 48.6 0.0 2.1e-12 47.5 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CBZ30327.1 - 0.082 12.5 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Glyco_hydro_65m PF03632.10 CBZ30329.1 - 3e-37 128.1 0.0 4.8e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.10 CBZ30329.1 - 1.6e-07 31.3 0.0 3.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain HAD_2 PF13419.1 CBZ30329.1 - 0.0041 17.3 0.0 0.011 15.9 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Kelch_4 PF13418.1 CBZ30330.1 - 3.1e-11 42.8 9.6 6.9e-06 25.7 0.0 5.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 CBZ30330.1 - 1.4e-10 40.5 0.9 0.00033 20.1 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 CBZ30330.1 - 5.5e-10 38.9 10.4 0.00021 21.1 0.2 6.3 7 0 0 7 7 7 2 Kelch motif Kelch_3 PF13415.1 CBZ30330.1 - 8.7e-10 38.4 18.1 1.9e-05 24.6 0.0 8.5 9 1 0 9 9 9 3 Galactose oxidase, central domain Kelch_6 PF13964.1 CBZ30330.1 - 6e-08 32.5 0.3 0.043 13.9 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 CBZ30330.1 - 0.034 13.9 5.1 34 4.4 0.0 5.4 5 0 0 5 5 5 0 Kelch motif HA2 PF04408.18 CBZ30331.1 - 1.5e-17 63.5 0.0 2.6e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CBZ30331.1 - 2.3e-12 46.6 0.0 6.1e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CBZ30331.1 - 3.1e-11 43.0 0.0 8e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CBZ30331.1 - 3.4e-08 33.1 0.8 1.9e-07 30.7 0.3 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ30331.1 - 5.4e-06 26.5 0.0 1.8e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 CBZ30331.1 - 0.0001 21.8 0.1 0.00032 20.2 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain T2SE PF00437.15 CBZ30331.1 - 0.00076 18.4 0.0 0.0016 17.3 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 CBZ30331.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CBZ30331.1 - 0.0018 18.1 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_29 PF13555.1 CBZ30331.1 - 0.0072 15.8 0.0 0.02 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CBZ30331.1 - 0.0075 16.2 1.6 0.18 11.7 0.2 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CBZ30331.1 - 0.012 15.7 0.0 0.071 13.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CBZ30331.1 - 0.018 14.6 0.0 0.048 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CBZ30331.1 - 0.027 13.9 0.1 0.61 9.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 CBZ30331.1 - 0.029 14.0 0.2 0.41 10.2 0.1 2.9 2 1 0 2 2 2 0 NACHT domain Flavi_DEAD PF07652.9 CBZ30331.1 - 0.03 14.0 0.2 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.22 CBZ30331.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.9 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 CBZ30331.1 - 0.098 12.1 0.0 0.58 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 CBZ30331.1 - 0.12 12.1 8.4 0.074 12.8 0.4 3.7 3 0 0 3 3 3 0 Part of AAA domain KaiC PF06745.8 CBZ30331.1 - 0.2 10.7 0.0 0.38 9.8 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 CBZ30331.1 - 0.35 11.1 0.1 0.66 10.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 CBZ30332.1 - 4.1e-18 65.7 0.0 2.2e-16 60.1 0.0 2.5 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 CBZ30332.1 - 2.2e-09 37.2 0.0 4.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CBZ30332.1 - 0.086 13.3 0.1 4.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein Cofilin_ADF PF00241.15 CBZ30334.1 - 1e-10 41.6 0.2 1.6e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Xlink PF00193.12 CBZ30335.1 - 0.56 10.3 3.2 0.99 9.5 0.3 2.6 3 0 0 3 3 3 0 Extracellular link domain MMgT PF10270.4 CBZ30337.1 - 0.00086 19.7 2.6 0.004 17.5 1.8 2.0 1 1 0 1 1 1 1 Membrane magnesium transporter Clat_adaptor_s PF01217.15 CBZ30338.1 - 3.6e-51 172.6 3.4 4e-51 172.4 2.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_2 PF00152.15 CBZ30339.1 - 7.8e-70 235.2 0.0 1.1e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.10 CBZ30339.1 - 1.7e-43 147.9 0.5 2.8e-43 147.2 0.4 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.20 CBZ30339.1 - 1.1e-10 41.1 0.0 2.6e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain zf-UDP PF14569.1 CBZ30340.1 - 0.056 13.1 0.6 0.13 12.0 0.1 1.8 1 1 1 2 2 2 0 Zinc-binding RING-finger HNH_5 PF14279.1 CBZ30340.1 - 0.059 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 HNH endonuclease DUF2046 PF09755.4 CBZ30341.1 - 1.7e-05 23.8 19.3 1.7e-05 23.8 13.4 2.9 2 1 1 3 3 3 2 Uncharacterized conserved protein H4 (DUF2046) TrmB PF01978.14 CBZ30341.1 - 0.021 14.5 1.7 0.063 12.9 0.6 2.3 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB ERM PF00769.14 CBZ30341.1 - 3.4 7.1 33.5 0.94 8.9 1.0 2.9 2 1 1 3 3 3 0 Ezrin/radixin/moesin family APG6 PF04111.7 CBZ30341.1 - 4.6 6.1 27.1 0.23 10.4 0.6 2.5 2 1 0 2 2 2 0 Autophagy protein Apg6 PRKCSH-like PF12999.2 CBZ30341.1 - 6.3 6.3 5.3 8.4 5.9 2.9 1.8 1 1 0 1 1 1 0 Glucosidase II beta subunit-like DUF3635 PF12330.3 CBZ30341.1 - 9.5 6.3 7.7 6.4 6.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3635) CBFD_NFYB_HMF PF00808.18 CBZ30342.1 - 1e-05 25.4 0.2 1.8e-05 24.6 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CBZ30342.1 - 0.00025 21.0 0.2 0.00044 20.2 0.2 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SDA1 PF05285.7 CBZ30342.1 - 0.39 9.9 5.9 0.54 9.4 4.1 1.2 1 0 0 1 1 1 0 SDA1 EF-hand_7 PF13499.1 CBZ30344.1 - 3.2e-22 78.4 4.1 5.1e-14 52.1 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ30344.1 - 3.5e-22 75.9 6.5 1.3e-07 30.3 0.9 3.5 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 CBZ30344.1 - 5.1e-20 69.5 4.0 2.5e-06 26.8 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 CBZ30344.1 - 2.1e-15 56.0 10.9 1.2e-12 47.1 0.8 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CBZ30344.1 - 2.1e-14 52.1 4.2 0.00048 19.3 0.5 3.5 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 CBZ30344.1 - 4.7e-12 45.6 0.3 3.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CBZ30344.1 - 8.9e-07 28.6 0.5 0.004 16.8 0.1 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF3164 PF11363.3 CBZ30344.1 - 0.0035 16.7 0.9 0.13 11.5 0.0 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF3164) Caleosin PF05042.8 CBZ30344.1 - 0.026 14.0 0.1 0.26 10.8 0.0 2.2 2 1 1 3 3 3 0 Caleosin related protein MgtE_N PF03448.12 CBZ30344.1 - 0.03 14.6 0.7 0.03 14.6 0.5 2.5 3 0 0 3 3 3 0 MgtE intracellular N domain TerB PF05099.8 CBZ30344.1 - 0.05 13.3 6.3 0.27 10.9 1.0 2.7 1 1 3 4 4 4 0 Tellurite resistance protein TerB SPARC_Ca_bdg PF10591.4 CBZ30344.1 - 0.075 13.0 2.0 1.5 8.8 0.3 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region LTXXQ PF07813.7 CBZ30344.1 - 0.53 10.7 6.3 8.5 6.8 4.4 2.2 1 1 0 1 1 1 0 LTXXQ motif family protein DUF1091 PF06477.8 CBZ30345.1 - 0.046 14.1 0.2 9.1 6.7 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1091) Aminotran_4 PF01063.14 CBZ30346.1 - 2.7e-27 95.7 0.0 3.7e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Glycos_transf_1 PF00534.15 CBZ30347.1 - 4.7e-27 94.4 0.0 8e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBZ30347.1 - 5.3e-06 26.6 0.0 1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBZ30347.1 - 0.00042 20.5 0.0 0.0017 18.5 0.0 2.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_11 PF13414.1 CBZ30348.1 - 5e-28 96.5 19.4 3e-12 46.0 1.0 4.7 3 2 1 4 4 4 3 TPR repeat DnaJ PF00226.26 CBZ30348.1 - 1.4e-20 72.7 0.1 3.6e-20 71.4 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 CBZ30348.1 - 9.8e-18 62.9 14.4 1.2e-05 24.6 0.1 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ30348.1 - 8.1e-15 53.4 24.6 0.00043 19.9 0.2 7.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ30348.1 - 1.3e-06 28.9 10.2 0.089 13.4 0.4 6.6 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ30348.1 - 7e-06 25.8 0.9 7e-06 25.8 0.6 5.4 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ30348.1 - 0.00019 20.9 14.4 0.0077 15.9 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ30348.1 - 0.00073 19.5 0.5 27 5.3 0.1 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBZ30348.1 - 0.0023 17.6 1.0 0.19 11.5 0.0 3.3 2 1 1 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.1 CBZ30348.1 - 0.02 15.4 12.5 2.9 8.7 0.6 6.7 4 2 4 8 8 7 0 Tetratricopeptide repeat Apc3 PF12895.2 CBZ30348.1 - 0.022 14.8 14.2 0.28 11.3 0.1 4.4 4 1 1 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CBZ30348.1 - 0.067 13.0 4.2 2 8.3 0.3 3.4 2 1 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ30348.1 - 0.2 11.5 10.8 9.4 6.3 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ30348.1 - 1.1 9.8 10.7 4.3 7.9 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Sec7 PF01369.15 CBZ30350.1 - 6.8e-53 179.1 0.0 1.1e-52 178.5 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CBZ30350.1 - 0.00083 18.8 1.6 1.3 8.4 0.6 2.8 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal GTP_EFTU PF00009.22 CBZ30351.1 - 2.1e-07 30.5 0.0 4.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CBZ30351.1 - 0.031 14.3 0.1 0.094 12.8 0.1 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 CBZ30351.1 - 0.037 13.5 1.2 2.1 7.7 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 CBZ30351.1 - 0.051 13.1 0.3 0.13 11.7 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CBZ30351.1 - 0.057 13.7 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 CBZ30351.1 - 0.17 11.2 0.1 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 CBZ30351.1 - 0.25 10.8 0.8 6.8 6.1 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_L35Ae PF01247.13 CBZ30352.1 - 3.2e-35 119.7 1.6 4.6e-35 119.2 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CBZ30352.1 - 7.2e-05 22.6 0.4 0.088 12.7 0.0 2.4 2 1 0 2 2 2 2 RimM N-terminal domain UPF0182 PF03699.8 CBZ30354.1 - 0.071 11.0 0.9 0.087 10.7 0.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) CENP-F_leu_zip PF10473.4 CBZ30356.1 - 0.0014 18.5 17.3 0.0014 18.5 12.0 8.9 2 2 7 9 9 9 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_S16 PF00886.14 CBZ30356.1 - 0.061 13.0 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein S16 LRR_6 PF13516.1 CBZ30357.1 - 5.6e-08 32.0 1.1 0.11 12.5 0.0 4.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 CBZ30357.1 - 0.0055 16.5 1.6 4.6 7.6 0.0 3.5 4 0 0 4 4 4 2 Leucine Rich Repeat BRX PF08381.6 CBZ30357.1 - 0.033 13.2 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 WD40 PF00400.27 CBZ30358.1 - 0.019 14.8 6.9 0.36 10.7 0.0 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat PP2C PF00481.16 CBZ30359.1 - 7e-53 179.6 0.0 9.2e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CBZ30359.1 - 0.00011 21.9 0.2 0.036 13.7 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 CBZ30359.1 - 0.00065 19.1 0.0 0.0017 17.8 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 CBZ30360.1 - 6.3e-54 183.0 0.0 7.2e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CBZ30360.1 - 0.019 14.3 0.0 0.047 13.0 0.0 1.7 1 1 0 1 1 1 0 Protein phosphatase 2C DUF4626 PF15422.1 CBZ30361.1 - 0.0081 16.1 1.9 0.015 15.2 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4626) Sec7 PF01369.15 CBZ30362.1 - 4.6e-48 163.4 0.0 4.7e-47 160.1 0.0 2.2 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.5 CBZ30362.1 - 1.3e-20 72.6 0.2 4.9e-20 70.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) Sec7_N PF12783.2 CBZ30362.1 - 4.5e-20 71.7 0.2 1.7e-19 69.8 0.2 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal FlgN PF05130.7 CBZ30363.1 - 0.0042 17.3 7.6 0.0042 17.3 5.3 15.3 7 3 11 18 18 18 1 FlgN protein SpoIISA_toxin PF14171.1 CBZ30363.1 - 0.084 12.1 2.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system AAA_13 PF13166.1 CBZ30363.1 - 2.8 6.3 100.2 0.0083 14.6 7.3 7.9 5 1 2 7 7 7 0 AAA domain GAS PF13851.1 CBZ30364.1 - 0.0046 16.1 13.1 0.0046 16.1 9.0 6.1 5 1 1 6 6 6 2 Growth-arrest specific micro-tubule binding C2 PF00168.25 CBZ30364.1 - 0.0067 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain Lebercilin PF15619.1 CBZ30364.1 - 0.0068 15.8 16.8 0.0068 15.8 11.7 6.1 4 1 1 5 5 5 2 Ciliary protein causing Leber congenital amaurosis disease Shugoshin_N PF07558.6 CBZ30364.1 - 0.0082 15.8 20.0 0.31 10.7 0.2 7.1 6 1 1 7 7 7 2 Shugoshin N-terminal coiled-coil region Reo_sigmaC PF04582.7 CBZ30364.1 - 0.12 11.5 7.0 0.21 10.7 0.1 3.8 4 1 1 5 5 5 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 CBZ30364.1 - 1.5 8.9 38.4 4.1 7.5 4.3 6.4 5 1 1 6 6 6 0 Fibrinogen alpha/beta chain family HC2 PF07382.6 CBZ30364.1 - 1.9 8.3 6.1 7.7 6.3 0.4 2.2 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 YkyA PF10368.4 CBZ30365.1 - 0.01 15.2 2.3 0.01 15.2 1.6 2.8 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein LemA PF04011.7 CBZ30365.1 - 0.025 13.6 0.5 0.055 12.5 0.3 1.5 1 0 0 1 1 1 0 LemA family IncA PF04156.9 CBZ30365.1 - 0.039 13.5 13.2 0.027 14.0 1.4 3.5 3 0 0 3 3 3 0 IncA protein Sec34 PF04136.10 CBZ30365.1 - 0.56 9.8 7.5 0.09 12.4 2.1 1.9 2 0 0 2 2 2 0 Sec34-like family V_ATPase_I PF01496.14 CBZ30365.1 - 0.61 7.8 4.9 0.36 8.6 0.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TPR_MLP1_2 PF07926.7 CBZ30365.1 - 5.5 6.7 22.6 3.5 7.3 4.2 3.7 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 CBZ30365.1 - 6.6 7.1 11.9 5.2 7.4 2.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Cast PF10174.4 CBZ30367.1 - 0.0039 15.3 57.2 0.048 11.7 18.1 2.1 2 0 0 2 2 2 2 RIM-binding protein of the cytomatrix active zone Corona_S2 PF01601.11 CBZ30367.1 - 0.0079 14.3 0.1 0.019 13.1 0.0 1.6 1 1 0 1 1 1 1 Coronavirus S2 glycoprotein Alba PF01918.16 CBZ30368.1 - 4.2e-14 51.8 0.2 6e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 CBZ30368.1 - 0.0048 16.5 0.1 0.006 16.2 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P GRP PF07172.6 CBZ30368.1 - 0.5 10.8 15.6 0.085 13.3 8.2 1.7 2 0 0 2 2 2 0 Glycine rich protein family Caprin-1_C PF12287.3 CBZ30368.1 - 6.3 6.0 8.9 8.2 5.7 6.2 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Adap_comp_sub PF00928.16 CBZ30369.1 - 3.7e-55 186.8 0.0 4.5e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CBZ30369.1 - 0.0022 17.7 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ACBP PF00887.14 CBZ30370.1 - 8e-20 70.3 2.0 8.8e-20 70.1 1.4 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein TIP49 PF06068.8 CBZ30371.1 - 2.1e-178 593.1 1.7 2.1e-178 593.1 1.2 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA PF00004.24 CBZ30371.1 - 9.7e-08 32.2 1.7 4.8e-05 23.5 0.1 3.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ30371.1 - 6.2e-07 29.6 1.2 0.068 13.3 0.0 3.3 2 1 0 3 3 3 2 AAA domain RuvB_N PF05496.7 CBZ30371.1 - 1e-06 28.0 1.0 0.00073 18.6 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 CBZ30371.1 - 1e-05 24.6 0.1 1.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.9 CBZ30371.1 - 1.7e-05 24.6 0.3 0.0033 17.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBZ30371.1 - 6.9e-05 22.1 1.2 0.0014 17.8 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CBZ30371.1 - 0.00012 22.1 0.1 0.0007 19.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CBZ30371.1 - 0.00053 19.6 0.1 0.0014 18.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CBZ30371.1 - 0.0017 17.8 0.0 0.0048 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 CBZ30371.1 - 0.0022 17.4 0.5 0.095 12.1 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 CBZ30371.1 - 0.0041 16.2 0.4 0.01 14.9 0.3 1.6 1 0 0 1 1 1 1 Zeta toxin UPF0079 PF02367.12 CBZ30371.1 - 0.0068 16.0 0.2 0.018 14.6 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 CBZ30371.1 - 0.0087 15.7 0.1 0.025 14.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Sigma54_activat PF00158.21 CBZ30371.1 - 0.016 14.7 0.1 5.7 6.3 0.1 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.7 CBZ30371.1 - 0.038 13.6 0.5 0.15 11.6 0.1 2.3 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 CBZ30371.1 - 0.049 13.6 0.1 3.9 7.5 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_28 PF13521.1 CBZ30371.1 - 0.066 13.1 0.1 0.16 11.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CBZ30371.1 - 0.085 12.7 0.1 0.27 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CBZ30371.1 - 0.12 11.9 0.2 0.33 10.5 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain KaiC PF06745.8 CBZ30371.1 - 0.12 11.4 4.6 0.045 12.8 0.9 1.9 2 1 0 2 2 2 0 KaiC IstB_IS21 PF01695.12 CBZ30371.1 - 0.15 11.4 1.5 0.2 11.0 0.3 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein SUV3_C PF12513.3 CBZ30372.1 - 9.3e-12 44.1 0.1 2.3e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CBZ30372.1 - 5.3e-07 29.4 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ30372.1 - 0.0004 19.9 0.0 0.0014 18.1 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Kinesin PF00225.18 CBZ30372.1 - 0.029 13.0 0.0 0.047 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinesin motor domain Hydrolase PF00702.21 CBZ30373.1 - 2.5e-16 60.7 1.9 7.5e-09 36.3 2.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ30373.1 - 3e-12 47.1 0.4 3.2e-11 43.7 0.3 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CBZ30373.1 - 2.9e-10 39.5 0.2 2.2e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_like2 PF13246.1 CBZ30373.1 - 3.5e-10 39.7 0.0 1.7e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBZ30373.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBZ30373.1 - 0.016 15.4 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CBZ30373.1 - 0.19 11.6 0.0 0.51 10.2 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF21 PF01595.15 CBZ30375.1 - 1.7e-32 112.1 1.0 1.7e-32 112.1 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 CBZ30375.1 - 4.1e-07 29.6 0.2 0.0068 16.1 0.1 2.5 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.24 CBZ30375.1 - 0.012 15.3 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Vps52 PF04129.7 CBZ30376.1 - 4.6e-17 61.7 2.4 8.4e-16 57.5 1.3 2.1 2 0 0 2 2 2 2 Vps52 / Sac2 family XOO_2897-deam PF14440.1 CBZ30376.1 - 0.009 15.7 0.1 3.7 7.2 0.0 2.8 3 0 0 3 3 3 2 Xanthomonas XOO_2897-like deaminase Tropomyosin_1 PF12718.2 CBZ30376.1 - 0.45 10.3 3.1 1.6 8.5 2.1 2.0 1 0 0 1 1 1 0 Tropomyosin like FAD_binding_1 PF00667.15 CBZ30377.1 - 8.9e-37 126.6 0.0 1.2e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CBZ30377.1 - 1.6e-22 80.0 0.0 3.9e-22 78.7 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 CBZ30377.1 - 9.4e-17 61.5 0.0 2.1e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FMN_dh PF01070.13 CBZ30377.1 - 0.094 11.5 0.0 0.34 9.6 0.0 1.8 2 0 0 2 2 2 0 FMN-dependent dehydrogenase WD40 PF00400.27 CBZ30378.1 - 4.4e-24 83.4 6.9 3.8e-07 29.7 0.2 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat R_equi_Vir PF05526.6 CBZ30378.1 - 0.039 13.5 0.5 4.5 6.8 0.0 3.1 3 0 0 3 3 3 0 Rhodococcus equi virulence-associated protein Apc4_WD40 PF12894.2 CBZ30378.1 - 0.12 11.9 0.1 0.94 9.0 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.17 CBZ30380.1 - 1.1e-11 44.1 0.0 2.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ30380.1 - 5.4e-09 35.8 0.0 9.5e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.3 CBZ30380.1 - 0.00011 22.1 0.5 0.00025 20.9 0.0 1.8 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G zf-PHD-like PF15446.1 CBZ30381.1 - 0.076 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain MFS_1 PF07690.11 CBZ30382.1 - 4.2e-24 84.9 24.4 2.6e-12 46.1 7.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_11 PF08241.7 CBZ30385.1 - 1e-08 35.5 0.0 0.00074 19.9 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain WBS_methylT PF12589.3 CBZ30385.1 - 3.2e-08 33.9 14.6 3.2e-08 33.9 10.1 2.3 2 1 0 2 2 2 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_31 PF13847.1 CBZ30385.1 - 1.6e-06 27.8 0.0 6.6e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ30385.1 - 2.6e-05 24.5 0.0 0.00037 20.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ30385.1 - 0.00013 22.3 0.0 0.014 15.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ30385.1 - 0.00045 20.7 0.2 0.00099 19.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ30385.1 - 0.00064 19.4 0.0 0.0013 18.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CDC45 PF02724.9 CBZ30385.1 - 8.1 4.3 11.7 0.28 9.1 2.4 2.0 2 0 0 2 2 2 0 CDC45-like protein FAM176 PF14851.1 CBZ30386.1 - 0.63 9.7 6.2 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 FAM176 family Metallophos PF00149.23 CBZ30388.1 - 2.3e-21 76.1 0.0 3.4e-18 65.7 0.0 2.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Ribosomal_S19e PF01090.14 CBZ30389.1 - 2.2e-45 153.4 0.0 2.7e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e SRP54 PF00448.17 CBZ30390.1 - 0.085 12.2 0.1 0.83 9.0 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TPR_12 PF13424.1 CBZ30390.1 - 3 7.8 7.9 0.7 9.8 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ30390.1 - 3.3 7.8 8.7 0.14 12.0 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.1 CBZ30391.1 - 4.5e-06 26.7 0.2 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CBZ30391.1 - 0.0002 21.4 0.0 0.00062 19.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ30391.1 - 0.0065 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CBZ30391.1 - 0.0088 16.8 0.2 0.029 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.10 CBZ30391.1 - 0.021 13.4 0.0 0.032 12.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_14 PF13173.1 CBZ30391.1 - 0.035 13.9 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 CBZ30391.1 - 0.036 13.5 1.6 0.049 13.1 0.0 2.0 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF892 PF05974.7 CBZ30391.1 - 0.043 13.6 2.5 2.1 8.1 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF892) MobB PF03205.9 CBZ30391.1 - 0.044 13.4 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CBZ30391.1 - 0.069 12.5 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CBZ30391.1 - 0.1 12.4 0.0 0.1 12.4 0.0 2.7 3 1 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 CBZ30391.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Peptidase_M14 PF00246.19 CBZ30392.1 - 2.6e-27 96.1 0.0 7.1e-27 94.7 0.0 1.7 2 0 0 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.9 CBZ30392.1 - 0.00041 19.3 0.0 0.00064 18.6 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 CBZ30392.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) cNMP_binding PF00027.24 CBZ30393.1 - 5.1e-23 80.7 0.2 3e-11 42.9 0.1 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 CBZ30393.1 - 0.0023 17.4 0.6 0.0091 15.4 0.0 2.2 2 0 0 2 2 2 1 Cupin domain Urm1 PF09138.6 CBZ30394.1 - 4.6e-26 90.7 0.0 5.2e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CBZ30394.1 - 1.5e-07 31.7 0.1 1.9e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 ThiS family TGS PF02824.16 CBZ30394.1 - 0.0062 16.3 0.2 0.012 15.3 0.2 1.5 1 0 0 1 1 1 1 TGS domain GTP_EFTU PF00009.22 CBZ30395.1 - 4.8e-30 104.3 0.1 6.8e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 CBZ30395.1 - 2.3e-08 34.0 0.6 5.5e-08 32.8 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CBZ30395.1 - 3.2e-07 30.3 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 CBZ30395.1 - 4.1e-05 23.1 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 SRPRB PF09439.5 CBZ30395.1 - 0.00029 20.1 0.6 0.0058 15.8 0.1 2.6 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 CBZ30395.1 - 0.0032 16.9 0.2 2.5 7.5 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CBZ30395.1 - 0.012 16.0 0.1 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 CBZ30395.1 - 0.014 14.8 1.2 0.053 12.9 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Hexapep PF00132.19 CBZ30396.1 - 3.2e-11 42.1 11.9 1.5e-07 30.6 1.0 3.2 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CBZ30396.1 - 9e-06 25.1 7.5 0.038 13.5 1.0 3.1 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Ribosomal_L3 PF00297.17 CBZ30398.1 - 9.2e-100 333.3 9.0 1.1e-99 333.0 6.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L3 PF00297.17 CBZ30399.1 - 9.2e-100 333.3 9.0 1.1e-99 333.0 6.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Patatin PF01734.17 CBZ30400.1 - 3.8e-09 36.7 1.0 1e-07 32.1 0.7 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase Thioredoxin PF00085.15 CBZ30402.1 - 0.046 13.4 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin EF-hand_1 PF00036.27 CBZ30404.1 - 1.4e-14 52.1 0.1 7.3e-05 21.7 0.0 5.9 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 CBZ30404.1 - 1.4e-14 53.9 0.0 6.5e-07 29.3 0.0 4.2 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.1 CBZ30404.1 - 3.4e-14 52.1 0.1 1.9e-09 37.0 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CBZ30404.1 - 1.2e-13 49.7 0.1 0.0014 18.3 0.0 6.3 7 0 0 7 7 7 4 EF-hand domain EF-hand_5 PF13202.1 CBZ30404.1 - 3.4e-12 45.1 0.5 0.021 14.1 0.0 5.6 6 0 0 6 6 6 3 EF hand DUF2313 PF10076.4 CBZ30404.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) WVELL PF14043.1 CBZ30404.1 - 0.089 12.4 0.2 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 WVELL protein EF-hand_10 PF14788.1 CBZ30404.1 - 0.11 12.1 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 EF hand Spc7 PF08317.6 CBZ30406.1 - 0.00028 19.6 10.6 0.00037 19.2 7.4 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein V_ATPase_I PF01496.14 CBZ30406.1 - 0.13 10.0 0.4 0.16 9.8 0.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SseC PF04888.7 CBZ30406.1 - 0.16 11.2 4.2 0.051 12.8 1.1 1.5 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family APG6 PF04111.7 CBZ30406.1 - 0.76 8.7 12.6 0.97 8.4 8.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 CBZ30406.1 - 0.99 9.2 17.7 1.5 8.7 12.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3287 PF11690.3 CBZ30406.1 - 0.99 9.4 9.7 0.74 9.8 4.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) Exonuc_VII_L PF02601.10 CBZ30406.1 - 1.3 8.1 7.6 1.6 7.8 5.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.10 CBZ30406.1 - 1.6 8.3 17.1 0.19 11.2 4.1 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF342 PF03961.8 CBZ30406.1 - 2.5 6.3 5.4 3.3 6.0 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Nup88 PF10168.4 CBZ30406.1 - 2.8 5.6 11.4 3.7 5.2 7.9 1.1 1 0 0 1 1 1 0 Nuclear pore component Lge1 PF11488.3 CBZ30406.1 - 5.3 7.3 13.8 0.89 9.7 3.3 2.2 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 CBZ30406.1 - 5.3 6.6 16.2 2.4 7.6 3.4 2.0 1 1 1 2 2 2 0 IncA protein NDK PF00334.14 CBZ30407.1 - 1.2e-13 51.0 0.0 1.9e-12 47.1 0.0 2.4 2 1 0 2 2 2 1 Nucleoside diphosphate kinase CENP-B_dimeris PF09026.5 CBZ30408.1 - 0.01 16.0 0.1 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LRR_6 PF13516.1 CBZ30408.1 - 0.014 15.4 0.0 1 9.6 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.28 CBZ30408.1 - 0.028 14.3 0.0 0.34 11.0 0.0 2.8 3 0 0 3 3 3 0 Leucine Rich Repeat HTH_32 PF13565.1 CBZ30408.1 - 0.035 14.8 0.4 0.37 11.6 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain Rhodanese PF00581.15 CBZ30410.1 - 1.1e-11 45.1 0.0 1.8e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.20 CBZ30411.1 - 4.6e-23 81.6 0.0 8.8e-23 80.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain RMP PF14996.1 CBZ30412.1 - 8.1e-09 35.5 5.3 8.1e-09 35.5 3.6 3.0 3 1 0 3 3 3 1 Retinal Maintenance Adeno_E1B_55K PF01696.12 CBZ30413.1 - 0.0002 19.9 0.8 0.0002 19.9 0.6 2.0 2 0 0 2 2 2 1 Adenovirus EB1 55K protein / large t-antigen Beta_helix PF13229.1 CBZ30413.1 - 0.00098 18.9 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 2 Right handed beta helix region EcKinase PF02958.15 CBZ30413.1 - 0.021 13.9 0.1 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Cyt-b5 PF00173.23 CBZ30414.1 - 1e-07 31.6 0.1 1.8e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mito_carr PF00153.22 CBZ30415.1 - 4.2e-47 157.8 5.6 2.6e-22 78.3 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein SWIM PF04434.12 CBZ30416.1 - 0.0065 15.9 10.5 0.053 13.0 1.9 3.4 3 0 0 3 3 3 2 SWIM zinc finger DNA_pol_A_exo1 PF01612.15 CBZ30417.1 - 8.7e-39 132.7 0.4 1.5e-38 131.9 0.3 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CBZ30417.1 - 6e-22 77.7 0.0 2.8e-21 75.6 0.0 2.1 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 CBZ30417.1 - 2.6e-08 33.4 0.0 5.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 HRDC domain PIP5K PF01504.13 CBZ30418.1 - 3.4e-69 232.7 0.0 4.9e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase AAA_33 PF13671.1 CBZ30420.1 - 6.1e-16 58.5 0.0 9.2e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ30420.1 - 9.2e-05 21.6 0.0 0.00016 20.8 0.0 1.3 1 1 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 CBZ30420.1 - 0.00076 18.7 0.0 0.00092 18.4 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CBZ30420.1 - 0.0013 19.5 0.0 0.0016 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CBZ30420.1 - 0.005 16.9 0.2 0.014 15.5 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CBZ30420.1 - 0.013 15.1 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPT PF03151.11 CBZ30421.1 - 7.5e-07 28.9 13.0 7.5e-07 28.9 9.0 2.8 2 2 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CBZ30421.1 - 0.00019 20.4 25.8 0.00046 19.2 17.9 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 CBZ30421.1 - 0.46 10.5 36.1 0.47 10.5 11.6 2.3 2 0 0 2 2 2 0 EamA-like transporter family Elf1 PF05129.8 CBZ30423.1 - 0.0016 18.0 0.5 0.0016 18.0 0.4 2.9 3 1 1 4 4 4 1 Transcription elongation factor Elf1 like zf-CCHC PF00098.18 CBZ30423.1 - 0.0045 16.8 3.1 0.0045 16.8 2.1 3.3 3 0 0 3 3 3 1 Zinc knuckle WW PF00397.21 CBZ30423.1 - 0.17 11.8 3.6 0.45 10.4 2.5 1.8 1 0 0 1 1 1 0 WW domain eIF3g PF12353.3 CBZ30423.1 - 0.35 10.7 19.8 0.49 10.3 3.6 3.8 1 1 2 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G DZR PF12773.2 CBZ30423.1 - 9.1 6.1 17.8 3.8 7.3 0.2 3.2 2 1 0 2 2 2 0 Double zinc ribbon Prefoldin PF02996.12 CBZ30425.1 - 0.058 13.0 0.0 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit Cytochrom_B562 PF07361.6 CBZ30425.1 - 0.67 10.4 5.6 14 6.1 0.1 3.1 3 0 0 3 3 3 0 Cytochrome b562 CesT PF05932.8 CBZ30426.1 - 9.7e-13 48.0 0.3 2.2e-12 46.8 0.2 1.6 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family bZIP_1 PF00170.16 CBZ30426.1 - 0.0066 16.3 0.3 0.0066 16.3 0.2 3.5 3 1 1 4 4 4 1 bZIP transcription factor ubiquitin PF00240.18 CBZ30426.1 - 0.011 15.1 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Atg14 PF10186.4 CBZ30426.1 - 0.024 13.5 2.7 0.036 13.0 1.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Rad60-SLD PF11976.3 CBZ30426.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RRF PF01765.14 CBZ30426.1 - 0.79 9.1 4.1 1.4 8.3 2.9 1.3 1 0 0 1 1 1 0 Ribosome recycling factor GBP_C PF02841.9 CBZ30426.1 - 1.9 7.5 9.1 2.9 7.0 6.3 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Selenoprotein_S PF06936.6 CBZ30426.1 - 7.8 5.9 9.4 3.3 7.1 4.4 1.8 1 1 0 1 1 1 0 Selenoprotein S (SelS) Epimerase PF01370.16 CBZ30428.1 - 2.9e-16 59.6 0.0 5.8e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBZ30428.1 - 6.1e-12 45.9 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CBZ30428.1 - 1.8e-07 30.6 0.0 7.9e-06 25.2 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 CBZ30428.1 - 2.7e-07 29.5 0.1 1.1e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.18 CBZ30428.1 - 0.074 12.8 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 CBZ30428.1 - 0.086 11.7 0.0 0.18 10.6 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein PPR_3 PF13812.1 CBZ30429.1 - 0.086 13.1 0.2 0.74 10.2 0.0 2.9 2 0 0 2 2 2 0 Pentatricopeptide repeat domain GCV_H PF01597.14 CBZ30430.1 - 0.00026 20.6 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein E1-E2_ATPase PF00122.15 CBZ30431.1 - 4.7e-21 74.8 0.0 1.2e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CBZ30431.1 - 3.6e-12 47.1 0.0 2.2e-08 34.7 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ30431.1 - 2.5e-09 37.6 0.2 5.9e-09 36.3 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ30431.1 - 4e-08 33.0 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CBZ30431.1 - 0.0016 18.1 0.2 0.0025 17.4 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.1 CBZ30431.1 - 0.042 14.0 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 CoA binding domain HA2 PF04408.18 CBZ30432.1 - 1.3e-15 57.2 0.0 4.5e-15 55.5 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) dsrm PF00035.20 CBZ30432.1 - 2.4e-11 44.0 0.0 0.0013 19.2 0.0 4.8 4 0 0 4 4 4 2 Double-stranded RNA binding motif Helicase_C PF00271.26 CBZ30432.1 - 1.6e-09 37.5 0.0 6.4e-09 35.5 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ30432.1 - 6.9e-07 28.9 0.1 1.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ30432.1 - 3.1e-05 24.1 0.1 0.0002 21.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CBZ30432.1 - 0.0029 17.5 0.2 0.054 13.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CBZ30432.1 - 0.029 13.8 0.0 0.067 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain KaiC PF06745.8 CBZ30432.1 - 0.029 13.4 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 CBZ30432.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPP_enzyme_N PF02776.13 CBZ30434.1 - 3.6e-34 117.7 0.1 6.4e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CBZ30434.1 - 4.5e-20 71.7 0.1 1.7e-19 69.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CBZ30434.1 - 7.4e-18 64.6 0.1 1.7e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.1 CBZ30434.1 - 0.14 11.0 0.0 0.32 9.8 0.0 1.6 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase DRMBL PF07522.9 CBZ30435.1 - 4.2e-19 68.6 0.0 7.7e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase DUF4379 PF14311.1 CBZ30436.1 - 3.2e-15 55.6 0.4 6.4e-15 54.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4379) HypA PF01155.14 CBZ30436.1 - 0.13 11.9 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-UBP PF02148.14 CBZ30437.1 - 9.6e-16 57.6 8.5 9.6e-16 57.6 5.9 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UPF0054 PF02130.12 CBZ30439.1 - 2.8e-39 133.7 0.0 3.2e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 LRR_4 PF12799.2 CBZ30440.1 - 0.00023 20.7 0.5 0.073 12.7 0.1 2.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CBZ30440.1 - 0.00041 20.1 4.2 3.4 8.0 0.3 4.4 4 0 0 4 4 4 1 Leucine Rich repeat LRR_8 PF13855.1 CBZ30440.1 - 0.12 12.1 2.7 1.8 8.3 0.2 2.7 1 1 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.28 CBZ30440.1 - 0.16 12.1 8.9 13 6.3 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 CBZ30440.1 - 0.87 10.0 3.0 30 5.4 0.1 4.5 5 0 0 5 5 5 0 Leucine rich repeat p450 PF00067.17 CBZ30442.1 - 3.8e-61 207.0 0.0 5.4e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1477 PF07346.6 CBZ30442.1 - 0.0031 17.5 0.3 0.0067 16.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1477) YukD PF08817.5 CBZ30442.1 - 0.035 14.6 0.0 0.093 13.3 0.0 1.7 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD AAA PF00004.24 CBZ30444.1 - 2.9e-35 121.3 0.0 5.5e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CBZ30444.1 - 2.9e-05 23.7 0.1 0.0002 21.0 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CBZ30444.1 - 3.5e-05 23.9 0.2 0.0072 16.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBZ30444.1 - 3.9e-05 23.3 0.0 0.00018 21.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CBZ30444.1 - 0.00014 22.6 0.0 0.00051 20.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ30444.1 - 0.00019 21.5 0.8 0.011 15.7 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 CBZ30444.1 - 0.0005 19.1 0.0 0.0019 17.2 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CBZ30444.1 - 0.00053 19.6 0.1 0.39 10.3 0.0 2.7 2 1 1 3 3 3 2 NACHT domain TIP49 PF06068.8 CBZ30444.1 - 0.0016 17.2 0.0 0.0098 14.6 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 CBZ30444.1 - 0.0022 17.8 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBZ30444.1 - 0.0046 16.3 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CBZ30444.1 - 0.0051 16.7 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CBZ30444.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CBZ30444.1 - 0.035 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CBZ30444.1 - 0.038 13.8 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 CBZ30444.1 - 0.06 12.4 0.1 0.25 10.5 0.0 2.0 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 CBZ30444.1 - 0.075 12.9 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 CBZ30444.1 - 0.13 12.4 0.0 0.81 9.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Tyr_Deacylase PF02580.11 CBZ30445.1 - 9.1e-44 148.9 0.0 1.1e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Aldose_epim PF01263.15 CBZ30447.1 - 1.4e-32 113.0 0.0 1.7e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF2389 PF09493.5 CBZ30447.1 - 0.01 16.1 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 2 Tryptophan-rich protein (DUF2389) HECT PF00632.20 CBZ30448.1 - 1.8e-07 30.6 0.0 0.042 13.0 0.0 3.0 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) DCP2 PF05026.8 CBZ30448.1 - 0.04 13.8 0.2 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 Dcp2, box A domain HECT PF00632.20 CBZ30449.1 - 4.2e-07 29.4 0.0 2.3e-06 26.9 0.2 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Lactamase_B PF00753.22 CBZ30451.1 - 2.6e-14 53.3 0.0 6.2e-14 52.1 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CBZ30451.1 - 0.04 13.4 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Beta-Casp PF10996.3 CBZ30452.1 - 2.8e-32 111.3 0.0 7.3e-32 109.9 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 CBZ30452.1 - 1.3e-19 70.5 0.0 2.2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CPSF73-100_C PF11718.3 CBZ30452.1 - 3.5e-11 42.8 0.0 6.6e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B_2 PF12706.2 CBZ30452.1 - 3.4e-09 36.5 0.1 8.3e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 CBZ30452.1 - 3.4e-08 33.1 0.0 9e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 CBZ30452.1 - 0.0001 22.0 0.0 0.00028 20.6 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Topoisom_I_N PF02919.10 CBZ30453.1 - 1.2e-94 315.5 1.2 1.2e-94 315.5 0.8 3.3 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CBZ30453.1 - 2.4e-83 278.8 0.5 2.4e-83 278.8 0.3 1.7 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core DUF4554 PF15091.1 CBZ30453.1 - 0.6 8.7 9.9 1 8.0 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) LRR_9 PF14580.1 CBZ30454.1 - 2.1e-05 24.1 0.1 3.9e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CBZ30454.1 - 0.00021 20.7 0.4 0.0055 16.2 0.0 2.6 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ30454.1 - 0.0063 16.2 0.5 0.0063 16.2 0.4 2.1 2 0 0 2 2 2 1 Leucine rich repeat bZIP_1 PF00170.16 CBZ30454.1 - 1 9.3 6.6 0.89 9.5 0.4 3.0 3 0 0 3 3 3 0 bZIP transcription factor zf-RanBP PF00641.13 CBZ30455.1 - 2.1e-05 23.5 2.6 2.1e-05 23.5 1.8 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF35_N PF12172.3 CBZ30455.1 - 0.096 12.6 3.3 0.35 10.8 2.3 2.0 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Amidinotransf PF02274.12 CBZ30456.1 - 2.9e-12 46.2 0.0 3.3e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Amidinotransferase DUF3387 PF11867.3 CBZ30456.1 - 0.018 14.0 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) DUF422 PF04240.7 CBZ30456.1 - 0.087 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF422) LRR_6 PF13516.1 CBZ30457.1 - 0.05 13.6 3.6 0.068 13.2 0.0 2.7 2 1 0 2 2 2 0 Leucine Rich repeat LRR_4 PF12799.2 CBZ30457.1 - 0.16 11.6 2.1 0.7 9.5 1.0 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) TPR_12 PF13424.1 CBZ30458.1 - 5.5e-40 135.1 48.5 1.2e-12 47.6 0.0 5.5 2 2 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ30458.1 - 4.5e-22 77.2 29.2 1e-06 28.4 0.0 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ30458.1 - 1.1e-11 44.2 24.4 7.5e-07 28.7 0.0 5.5 2 2 4 6 6 6 5 TPR repeat TPR_8 PF13181.1 CBZ30458.1 - 3.4e-10 38.9 17.4 0.00088 18.8 0.1 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ30458.1 - 0.0008 19.8 31.0 3.4 8.5 0.1 7.8 6 2 2 8 8 7 2 Tetratricopeptide repeat ATG16 PF08614.6 CBZ30458.1 - 0.002 17.9 0.8 1.6 8.4 0.0 2.6 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) Drf_FH3 PF06367.11 CBZ30458.1 - 0.0034 16.8 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Diaphanous FH3 Domain TPR_16 PF13432.1 CBZ30458.1 - 0.073 13.7 31.8 0.36 11.5 0.3 6.2 4 2 3 7 7 6 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 CBZ30458.1 - 0.1 12.4 1.0 19 5.1 0.0 3.5 2 1 2 4 4 4 0 Rapsyn N-terminal myristoylation and linker region TPR_7 PF13176.1 CBZ30458.1 - 0.13 12.0 21.6 1.8 8.5 0.0 7.4 8 1 0 8 8 8 0 Tetratricopeptide repeat DUF3301 PF11743.3 CBZ30458.1 - 0.17 11.4 2.7 9 5.8 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3301) TPR_19 PF14559.1 CBZ30458.1 - 0.5 10.7 14.9 0.84 10.0 1.5 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ30458.1 - 2 8.1 18.6 13 5.5 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF1771 PF08590.5 CBZ30458.1 - 4.8 7.2 13.6 4.5 7.3 0.6 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1771) TIP49 PF06068.8 CBZ30459.1 - 2.7e-184 612.5 2.8 3.1e-184 612.2 1.9 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CBZ30459.1 - 1.6e-13 50.2 1.2 4.5e-08 32.4 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CBZ30459.1 - 1e-11 45.1 1.0 3.4e-07 30.5 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ30459.1 - 7.5e-07 29.3 0.1 0.04 14.0 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CBZ30459.1 - 5.1e-06 26.5 0.0 0.00046 20.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 CBZ30459.1 - 0.00019 20.6 0.3 0.011 14.9 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CBZ30459.1 - 0.00022 20.9 0.2 0.074 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CBZ30459.1 - 0.00024 20.5 0.0 0.00042 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ30459.1 - 0.0012 18.5 0.6 0.0039 16.9 0.3 2.0 1 1 1 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 CBZ30459.1 - 0.0027 17.6 0.0 0.017 14.9 0.0 2.3 4 0 0 4 4 2 1 AAA domain IstB_IS21 PF01695.12 CBZ30459.1 - 0.0037 16.7 0.4 0.022 14.1 0.1 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 CBZ30459.1 - 0.0053 17.5 0.0 0.02 15.7 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CBZ30459.1 - 0.0081 16.0 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CBZ30459.1 - 0.011 16.0 0.3 0.097 12.9 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CBZ30459.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 CBZ30459.1 - 0.018 13.7 0.8 0.38 9.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.10 CBZ30459.1 - 0.028 13.2 0.0 0.06 12.2 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_11 PF13086.1 CBZ30459.1 - 0.029 13.9 0.1 0.067 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain MinE PF03776.9 CBZ30459.1 - 0.03 13.8 0.2 0.073 12.5 0.1 1.6 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE ResIII PF04851.10 CBZ30459.1 - 0.035 13.9 0.3 0.81 9.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 CBZ30459.1 - 0.055 12.9 0.1 9.8 5.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 CBZ30459.1 - 0.066 12.3 0.2 0.19 10.7 0.1 1.7 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 CBZ30459.1 - 0.089 12.4 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 CBZ30459.1 - 0.09 11.7 0.1 0.18 10.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 CBZ30459.1 - 0.12 12.5 0.1 0.43 10.7 0.0 2.0 2 0 0 2 2 1 0 RNA helicase SET PF00856.23 CBZ30460.1 - 0.0014 18.9 0.0 0.0019 18.4 0.0 1.5 1 1 0 1 1 1 1 SET domain AAA PF00004.24 CBZ30461.1 - 9.1e-49 165.0 0.0 7.6e-38 129.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CBZ30461.1 - 3.9e-21 74.8 0.2 8.9e-21 73.7 0.1 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 CBZ30461.1 - 3.3e-11 43.5 1.9 0.00016 21.7 0.1 4.1 3 2 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 CBZ30461.1 - 1.2e-08 35.1 0.1 0.0067 16.5 0.0 3.2 3 1 1 4 4 2 2 AAA domain DUF815 PF05673.8 CBZ30461.1 - 5.1e-07 28.8 0.0 0.00078 18.4 0.0 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_33 PF13671.1 CBZ30461.1 - 1.9e-06 27.7 0.0 0.028 14.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CBZ30461.1 - 2.8e-06 27.2 0.0 0.0033 17.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CBZ30461.1 - 2.7e-05 23.6 0.0 0.053 13.0 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.9 CBZ30461.1 - 3.2e-05 23.6 0.0 0.07 12.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CBZ30461.1 - 4e-05 23.1 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ATP-synt_ab PF00006.20 CBZ30461.1 - 5.9e-05 22.6 0.0 0.043 13.3 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain ABC_tran PF00005.22 CBZ30461.1 - 0.0001 22.6 0.0 0.36 11.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter T2SE PF00437.15 CBZ30461.1 - 0.00011 21.1 0.0 0.13 11.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 CBZ30461.1 - 0.00012 22.8 0.1 0.019 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CBZ30461.1 - 0.00014 21.9 0.0 0.056 13.6 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_28 PF13521.1 CBZ30461.1 - 0.00016 21.6 0.0 0.14 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 CBZ30461.1 - 0.00029 20.8 0.0 0.052 13.6 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 CBZ30461.1 - 0.00033 20.4 0.0 0.23 11.1 0.0 3.1 2 1 1 3 3 3 1 Archaeal ATPase Vps4_C PF09336.5 CBZ30461.1 - 0.00036 20.3 0.0 0.00091 19.0 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 CBZ30461.1 - 0.00051 19.9 0.0 0.0016 18.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 CBZ30461.1 - 0.00071 19.0 1.9 6.4 6.1 0.0 4.7 3 1 2 5 5 5 0 AAA domain DUF258 PF03193.11 CBZ30461.1 - 0.001 18.2 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 CBZ30461.1 - 0.0022 17.1 0.0 0.95 8.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CBZ30461.1 - 0.0024 17.3 0.1 2.9 7.3 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain NACHT PF05729.7 CBZ30461.1 - 0.0038 16.8 0.6 1.9 8.1 0.0 3.9 3 1 1 4 4 4 1 NACHT domain Zeta_toxin PF06414.7 CBZ30461.1 - 0.0049 15.9 0.0 2.1 7.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 CBZ30461.1 - 0.0062 16.8 0.0 3.7 7.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CBZ30461.1 - 0.0084 15.6 0.0 0.05 13.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 CBZ30461.1 - 0.02 15.4 0.0 2.3 8.7 0.0 3.0 3 0 0 3 3 2 0 Miro-like protein Rad17 PF03215.10 CBZ30461.1 - 0.037 12.7 0.0 1.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 CBZ30461.1 - 0.062 12.7 0.0 5.7 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain NB-ARC PF00931.17 CBZ30461.1 - 0.11 11.3 0.0 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 CBZ30461.1 - 0.11 12.2 0.2 5.7 6.6 0.1 2.5 2 0 0 2 2 2 0 NTPase Bac_DnaA PF00308.13 CBZ30461.1 - 0.12 12.0 0.0 4.5 6.8 0.0 2.9 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_24 PF13479.1 CBZ30461.1 - 0.27 10.7 0.1 4.3 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain LicD PF04991.8 CBZ30463.1 - 3.2e-14 53.5 0.0 1.1e-06 28.9 0.0 2.1 1 1 1 2 2 2 2 LicD family Deltaretro_Tax PF05599.6 CBZ30463.1 - 0.059 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Deltaretrovirus Tax protein PDCD2_C PF04194.8 CBZ30464.1 - 2e-21 76.3 0.3 4.3e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Elf1 PF05129.8 CBZ30464.1 - 0.05 13.3 0.6 0.3 10.7 0.2 2.1 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Ank_2 PF12796.2 CBZ30465.1 - 6e-31 106.6 2.7 3.6e-16 59.2 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ30465.1 - 1.9e-29 99.9 2.9 2.8e-08 33.1 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 CBZ30465.1 - 5.2e-23 80.9 1.0 1.2e-05 25.6 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ30465.1 - 4.8e-21 72.7 0.8 1.5e-05 24.8 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CBZ30465.1 - 3.4e-20 71.6 7.9 9.9e-07 28.8 0.9 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Methyltransf_26 PF13659.1 CBZ30467.1 - 0.017 15.1 0.1 0.32 11.0 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain PI3_PI4_kinase PF00454.22 CBZ30468.1 - 1.7e-34 119.3 0.3 7.3e-33 113.9 0.0 2.8 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase SieB PF14163.1 CBZ30468.1 - 0.083 12.4 0.1 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Superinfection exclusion protein B PfkB PF00294.19 CBZ30469.1 - 3.6e-41 141.2 0.3 1.2e-40 139.5 0.2 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Complex1_LYR PF05347.10 CBZ30470.1 - 3.8e-11 42.6 0.4 6.5e-11 41.8 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CBZ30470.1 - 9.6e-09 35.3 0.3 1.8e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Herpes_UL14 PF03580.9 CBZ30470.1 - 0.068 12.9 0.1 0.31 10.8 0.0 1.8 1 1 1 2 2 2 0 Herpesvirus UL14-like protein DUF3336 PF11815.3 CBZ30471.1 - 4.5e-25 87.8 0.0 9.3e-25 86.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CBZ30471.1 - 2.7e-10 40.5 0.2 5.2e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Metallophos PF00149.23 CBZ30472.1 - 0.0031 16.9 0.0 0.051 12.9 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF2975 PF11188.3 CBZ30473.1 - 0.01 15.5 0.4 0.014 15.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) DUF2975 PF11188.3 CBZ30474.1 - 0.0076 15.9 0.0 0.0091 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2975) UCR_6-4kD PF08997.5 CBZ30474.1 - 0.053 13.2 0.2 0.098 12.3 0.1 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Arif-1 PF06770.6 CBZ30474.1 - 0.084 12.2 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) DUF2975 PF11188.3 CBZ30475.1 - 0.022 14.4 0.5 0.03 14.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Ribosomal_L21e PF01157.13 CBZ30476.1 - 1.9e-35 120.6 2.9 2.8e-35 120.1 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Ribosomal_S10 PF00338.17 CBZ30476.1 - 0.13 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e EMP70 PF02990.11 CBZ30477.1 - 1.4e-113 380.1 0.8 1.8e-113 379.8 0.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ATP-synt_ab PF00006.20 CBZ30478.1 - 2e-108 360.8 0.0 3.2e-108 360.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CBZ30478.1 - 2e-24 86.2 0.2 3.3e-24 85.5 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CBZ30478.1 - 2.3e-15 56.5 1.3 2.3e-15 56.5 0.9 2.3 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain DUF2737 PF10930.3 CBZ30478.1 - 0.069 12.7 0.1 12 5.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) AAA_14 PF13173.1 CBZ30478.1 - 0.13 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ribosomal_L13 PF00572.13 CBZ30479.1 - 4.6e-30 104.2 0.0 5.9e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ins_P5_2-kin PF06090.7 CBZ30481.1 - 8.4e-18 64.4 0.0 1.8e-17 63.3 0.0 1.5 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF501 PF04417.7 CBZ30483.1 - 6.3e-33 113.5 0.3 1.1e-32 112.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF501) zf-HC2 PF13490.1 CBZ30484.1 - 0.21 11.5 4.2 0.9 9.5 0.3 3.0 2 0 0 2 2 2 0 Putative zinc-finger Aminotran_1_2 PF00155.16 CBZ30485.1 - 2e-45 155.3 0.0 2.5e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBZ30485.1 - 0.0045 16.1 0.0 0.0079 15.3 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Metal_resist PF13801.1 CBZ30485.1 - 0.026 14.4 1.2 0.42 10.6 0.1 2.5 2 0 0 2 2 2 0 Heavy-metal resistance DUF3650 PF12368.3 CBZ30485.1 - 0.76 9.3 4.2 6.7 6.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) LIM PF00412.17 CBZ30487.1 - 0.14 12.2 7.8 0.34 11.0 5.4 1.7 1 0 0 1 1 1 0 LIM domain Actin PF00022.14 CBZ30488.1 - 1.9e-39 135.1 0.0 6.6e-39 133.4 0.0 1.7 1 1 0 1 1 1 1 Actin PGM_PMM_I PF02878.11 CBZ30490.1 - 5.7e-37 126.2 0.1 1.3e-36 125.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CBZ30490.1 - 2.1e-20 72.9 0.0 6.4e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CBZ30490.1 - 2.1e-13 50.2 0.0 5.6e-13 48.9 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CBZ30490.1 - 1.1e-05 25.3 0.0 3.9e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain WD40 PF00400.27 CBZ30491.1 - 0.039 13.8 0.6 1.6 8.7 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF164 PF02591.10 CBZ30493.1 - 0.0045 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Putative zinc ribbon domain Ribosomal_L14 PF00238.14 CBZ30494.1 - 6.4e-13 48.5 0.0 1.2e-12 47.6 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L14p/L23e TPR_11 PF13414.1 CBZ30495.1 - 3.8e-13 48.8 6.7 1e-07 31.4 1.5 3.0 3 1 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 CBZ30495.1 - 1e-09 37.5 3.2 0.046 13.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ30495.1 - 7e-09 34.9 4.6 0.13 12.1 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ30495.1 - 1.1e-05 25.2 2.3 0.0082 16.0 0.4 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ30495.1 - 0.0024 18.5 0.8 0.57 10.9 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ30495.1 - 0.018 14.8 6.3 9.3 6.2 1.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2464 PF10240.4 CBZ30495.1 - 0.029 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) TPR_19 PF14559.1 CBZ30495.1 - 0.03 14.6 0.2 5.1 7.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Exonuc_VIII PF06630.6 CBZ30495.1 - 0.065 12.5 1.1 3.7 6.8 0.1 2.1 2 0 0 2 2 2 0 Enterobacterial exodeoxyribonuclease VIII Apc3 PF12895.2 CBZ30495.1 - 0.08 13.0 4.6 1.1 9.4 2.4 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBZ30495.1 - 0.26 11.8 1.5 17 6.1 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Atg14 PF10186.4 CBZ30496.1 - 0.00021 20.3 12.2 0.00021 20.3 8.5 1.9 1 1 1 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Borrelia_P83 PF05262.6 CBZ30496.1 - 0.017 13.4 2.1 0.019 13.2 1.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein IncA PF04156.9 CBZ30496.1 - 0.025 14.1 11.8 0.16 11.5 7.3 2.0 2 0 0 2 2 2 0 IncA protein hDGE_amylase PF14701.1 CBZ30496.1 - 0.16 10.8 0.6 0.19 10.5 0.4 1.1 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme V_ATPase_I PF01496.14 CBZ30496.1 - 1.7 6.3 4.7 2.9 5.6 3.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family VIT1 PF01988.14 CBZ30496.1 - 4.7 6.6 5.0 16 4.8 3.5 1.9 1 1 0 1 1 1 0 VIT family DivIVA PF05103.8 CBZ30496.1 - 8.6 6.4 13.7 3.1 7.8 6.7 2.0 2 0 0 2 2 2 0 DivIVA protein MIP PF00230.15 CBZ30498.1 - 1.3e-34 119.6 19.5 9e-34 116.8 13.5 1.9 1 1 0 1 1 1 1 Major intrinsic protein LSM PF01423.17 CBZ30499.1 - 3.2e-12 45.8 0.2 4.5e-12 45.3 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBZ30499.1 - 0.0051 16.7 0.2 0.0079 16.1 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DnaJ PF00226.26 CBZ30500.1 - 6.6e-19 67.4 0.0 1.3e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_14 PF13428.1 CBZ30500.1 - 0.054 14.1 6.8 4.2 8.2 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ30500.1 - 0.072 12.7 0.2 0.072 12.7 0.1 3.4 4 1 0 5 5 5 0 TPR repeat TPR_16 PF13432.1 CBZ30500.1 - 0.38 11.4 10.1 6.3 7.6 0.2 4.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ30500.1 - 0.47 10.3 7.2 7.9 6.4 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Dynein_heavy PF03028.10 CBZ30501.1 - 1.9e-216 720.3 0.0 1.9e-216 720.3 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 CBZ30501.1 - 1.7e-128 429.5 0.3 1.7e-128 429.5 0.2 3.2 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 CBZ30501.1 - 4.7e-123 410.7 7.1 4.7e-123 410.7 4.9 4.9 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 CBZ30501.1 - 2.8e-101 337.8 0.0 7.1e-101 336.5 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 CBZ30501.1 - 9.3e-70 234.6 0.0 1.6e-69 233.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CBZ30501.1 - 1.8e-53 181.4 0.1 1.1e-52 178.8 0.0 2.4 2 1 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_9 PF12781.2 CBZ30501.1 - 5.5e-47 159.5 0.1 1.2e-46 158.3 0.0 1.6 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 MT PF12777.2 CBZ30501.1 - 8.8e-42 143.0 8.2 1.5e-41 142.3 5.7 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 CBZ30501.1 - 1.2e-21 76.9 0.2 3.8e-07 29.9 0.0 6.9 5 2 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA PF00004.24 CBZ30501.1 - 2.8e-07 30.7 3.2 0.64 10.2 0.0 6.6 6 0 0 6 6 5 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ30501.1 - 1.4e-05 25.2 2.3 1.8 8.7 0.0 5.7 6 0 0 6 6 4 2 AAA domain DUF258 PF03193.11 CBZ30501.1 - 0.00014 21.0 1.4 0.022 13.9 0.1 3.4 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 CBZ30501.1 - 0.00092 20.0 0.7 9.1 7.1 0.0 4.9 5 0 0 5 5 3 0 AAA domain AAA_33 PF13671.1 CBZ30501.1 - 0.0015 18.3 2.4 0.46 10.3 0.0 4.9 5 0 0 5 5 4 1 AAA domain AAA_29 PF13555.1 CBZ30501.1 - 0.0033 16.8 0.3 0.073 12.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CBZ30501.1 - 0.0061 16.8 2.1 1.1 9.5 0.0 4.2 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 CBZ30501.1 - 0.032 14.4 2.3 2.3 8.4 0.0 3.5 3 0 0 3 3 3 0 RNA helicase MobB PF03205.9 CBZ30501.1 - 0.055 13.1 3.2 0.93 9.1 0.1 3.2 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Tautomerase PF01361.16 CBZ30501.1 - 0.084 12.4 0.3 3.5 7.2 0.0 3.4 3 0 0 3 3 3 0 Tautomerase enzyme SMC_N PF02463.14 CBZ30501.1 - 0.14 11.3 0.1 1.8 7.7 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Carla_C4 PF01623.12 CBZ30501.1 - 0.5 10.1 1.9 2.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein ODV-E18 PF10717.4 CBZ30502.1 - 0.04 13.3 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 HATPase_c PF02518.21 CBZ30503.1 - 3.1e-15 55.8 0.0 8.6e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBZ30503.1 - 0.00036 20.2 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pet191_N PF10203.4 CBZ30504.1 - 3e-17 62.4 3.2 3.9e-17 62.0 2.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 AFP PF02420.10 CBZ30504.1 - 0.075 13.2 2.3 2.4 8.5 0.1 2.5 2 0 0 2 2 2 0 Insect antifreeze protein repeat NIF PF03031.13 CBZ30505.1 - 2.4e-27 95.5 0.0 3.7e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.7 CBZ30505.1 - 0.00022 20.3 0.0 0.00031 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) HAD_2 PF13419.1 CBZ30505.1 - 0.075 13.2 0.0 0.41 10.8 0.0 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase LBP_BPI_CETP_C PF02886.12 CBZ30506.1 - 0.06 12.5 0.4 0.4 9.8 0.0 2.4 3 0 0 3 3 3 0 LBP / BPI / CETP family, C-terminal domain PI3_PI4_kinase PF00454.22 CBZ30507.1 - 1.9e-50 171.5 0.2 3.8e-50 170.5 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CBZ30507.1 - 9.7e-24 83.9 0.1 2.9e-23 82.4 0.1 1.9 1 1 0 1 1 1 1 FAT domain Rapamycin_bind PF08771.6 CBZ30507.1 - 5.3e-20 71.3 0.3 2.6e-19 69.1 0.2 2.3 1 0 0 1 1 1 1 Rapamycin binding domain DUF3385 PF11865.3 CBZ30507.1 - 1.3e-13 51.2 1.3 8e-13 48.6 0.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FATC PF02260.15 CBZ30507.1 - 1.7e-13 49.7 0.4 9.5e-13 47.3 0.0 2.3 2 0 0 2 2 2 1 FATC domain PDZ PF00595.19 CBZ30507.1 - 0.0002 21.4 0.1 0.0005 20.1 0.1 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CBZ30507.1 - 0.22 11.4 0.0 0.58 10.0 0.0 1.6 1 0 0 1 1 1 0 PDZ domain DivIC PF04977.10 CBZ30508.1 - 0.0057 16.1 0.7 0.009 15.4 0.5 1.2 1 0 0 1 1 1 1 Septum formation initiator UPF0184 PF03670.8 CBZ30508.1 - 0.043 13.9 0.2 0.08 13.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Tmemb_cc2 PF10267.4 CBZ30508.1 - 0.07 11.7 0.2 0.1 11.1 0.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF4140 PF13600.1 CBZ30508.1 - 0.12 12.7 0.4 0.23 11.9 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) PIG-Y PF15159.1 CBZ30509.1 - 0.016 15.3 2.8 0.022 14.9 1.9 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PIG-Y PF15159.1 CBZ30510.1 - 8.4e-06 25.9 1.7 1.4e-05 25.2 1.2 1.4 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y ABG_transport PF03806.8 CBZ30510.1 - 0.0081 14.2 0.3 0.0089 14.0 0.2 1.0 1 0 0 1 1 1 1 AbgT putative transporter family Permease PF02405.11 CBZ30510.1 - 0.0085 15.5 0.0 0.0098 15.3 0.0 1.1 1 0 0 1 1 1 1 Permease DUF2569 PF10754.4 CBZ30510.1 - 0.035 14.3 0.8 0.04 14.1 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) HECT PF00632.20 CBZ30511.1 - 1.9e-52 178.4 0.0 5.2e-52 176.9 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.15 CBZ30512.1 - 2.6e-72 243.8 9.5 3.5e-72 243.4 6.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CBZ30512.1 - 3.4e-12 46.6 0.0 6.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Ribosomal_L7Ae PF01248.21 CBZ30513.1 - 2.7e-19 68.4 0.3 3.3e-19 68.1 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rgp1 PF08737.5 CBZ30514.1 - 3e-07 29.8 0.2 0.0013 17.9 0.0 2.2 2 0 0 2 2 2 2 Rgp1 Arrestin_N PF00339.24 CBZ30514.1 - 0.12 12.1 0.2 0.72 9.6 0.0 2.1 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Peptidase_C78 PF07910.8 CBZ30515.1 - 1e-50 171.8 0.0 1.5e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 FANCI_S1-cap PF14674.1 CBZ30517.1 - 0.025 14.6 0.6 0.43 10.6 0.1 2.3 2 0 0 2 2 2 0 FANCI solenoid 1 cap DUF445 PF04286.7 CBZ30517.1 - 0.048 13.1 3.4 0.064 12.7 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) UNC45-central PF11701.3 CBZ30517.1 - 0.11 12.1 1.7 0.22 11.1 1.2 1.4 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central Prenyltrans PF00432.16 CBZ30518.1 - 8.3e-71 233.1 17.6 1.2e-14 53.5 0.3 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CBZ30518.1 - 5.8e-42 142.6 0.1 3e-19 69.4 0.0 3.3 1 1 2 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CBZ30518.1 - 5.7e-15 55.2 0.1 3.6e-06 26.9 0.0 4.3 1 1 3 4 4 4 4 Prenyltransferase-like A2M_comp PF07678.9 CBZ30518.1 - 0.1 11.8 0.0 6.9 5.8 0.0 3.4 2 1 2 4 4 4 0 A-macroglobulin complement component UCH PF00443.24 CBZ30521.1 - 9.4e-37 126.5 0.2 1.4e-36 126.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ30521.1 - 2e-17 63.5 0.0 3.4e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Herpes_HEPA PF03324.9 CBZ30522.1 - 0.012 15.6 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus DNA helicase/primase complex associated protein MerR PF00376.18 CBZ30522.1 - 0.12 11.9 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 MerR family regulatory protein DUF342 PF03961.8 CBZ30522.1 - 4.6 5.5 4.9 83 1.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF342) DnaJ PF00226.26 CBZ30523.1 - 2.6e-07 30.2 0.2 7.7e-07 28.7 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain GRIP PF01465.15 CBZ30524.1 - 2e-12 46.4 0.0 5.7e-12 44.9 0.0 1.9 1 0 0 1 1 1 1 GRIP domain Exonuc_VII_L PF02601.10 CBZ30524.1 - 0.00049 19.3 8.3 0.00049 19.3 5.7 1.8 2 0 0 2 2 2 1 Exonuclease VII, large subunit GAGA_bind PF06217.7 CBZ30524.1 - 0.052 13.5 8.7 0.09 12.7 6.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family AAA_13 PF13166.1 CBZ30524.1 - 0.056 11.8 5.9 0.083 11.3 4.1 1.2 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 CBZ30524.1 - 0.29 10.3 30.4 1 8.5 0.0 3.3 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 CBZ30524.1 - 1.5 8.6 10.0 1.9 8.2 4.6 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phlebovirus_NSM PF07246.6 CBZ30524.1 - 2 7.4 10.3 0.14 11.2 3.4 1.8 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M DUF3829 PF12889.2 CBZ30524.1 - 5.8 6.0 8.5 1.8 7.7 1.9 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3829) NAD_binding_3 PF03447.11 CBZ30526.1 - 0.0039 17.5 1.7 0.024 15.0 0.2 3.1 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 CBZ30527.1 - 2.2e-10 40.7 0.4 2.8e-10 40.4 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ30527.1 - 0.0004 20.0 0.1 0.018 14.5 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold C8 PF08742.6 CBZ30527.1 - 0.19 12.0 0.4 1.9 8.7 0.0 2.4 2 1 1 3 3 3 0 C8 domain DUF1620 PF07774.8 CBZ30528.1 - 1.9e-49 167.8 0.0 3.4e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_3 PF13570.1 CBZ30528.1 - 0.00037 20.6 4.2 1.3 9.3 0.1 4.5 4 0 0 4 4 4 2 PQQ-like domain DHC_N2 PF08393.8 CBZ30531.1 - 4.3e-118 394.3 1.5 4.3e-118 394.3 1.0 5.2 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 CBZ30531.1 - 7.6e-114 381.2 1.3 9.7e-114 380.9 0.0 1.8 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 CBZ30531.1 - 3.2e-83 278.8 0.1 4.2e-82 275.1 0.0 2.7 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region D1 DHC_N1 PF08385.7 CBZ30531.1 - 5e-36 124.2 5.7 1.1e-34 119.8 0.0 4.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.9 CBZ30531.1 - 1.6e-34 118.6 0.0 2.1e-21 76.0 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_9 PF12781.2 CBZ30531.1 - 4.2e-33 114.1 0.1 1.6e-32 112.2 0.1 2.1 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 CBZ30531.1 - 2.1e-27 95.7 0.4 2.1e-26 92.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.2 CBZ30531.1 - 5.3e-26 91.1 10.5 1.3e-25 89.9 7.3 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.2 CBZ30531.1 - 1.7e-19 69.9 0.1 3.7e-18 65.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_16 PF13191.1 CBZ30531.1 - 1.5e-14 54.3 1.0 7.6e-05 22.7 0.0 5.9 5 0 0 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 CBZ30531.1 - 1.2e-12 48.0 0.0 0.00084 19.4 0.0 4.7 3 0 0 3 3 3 3 AAA domain AAA PF00004.24 CBZ30531.1 - 2.7e-11 43.7 0.0 0.021 14.9 0.0 4.5 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ30531.1 - 7.7e-09 36.4 0.2 0.00045 21.0 0.0 6.0 5 1 0 5 5 4 1 AAA domain AAA_28 PF13521.1 CBZ30531.1 - 1.7e-07 31.3 0.1 0.052 13.4 0.0 4.7 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.1 CBZ30531.1 - 1.9e-07 31.0 0.0 0.0053 16.6 0.0 3.7 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 CBZ30531.1 - 5e-07 29.8 0.0 0.19 11.8 0.0 3.7 3 0 0 3 3 3 1 RNA helicase DUF258 PF03193.11 CBZ30531.1 - 7.4e-07 28.4 0.0 0.00064 18.9 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 CBZ30531.1 - 4.2e-06 26.6 0.1 0.06 13.2 0.0 4.4 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 CBZ30531.1 - 4.3e-06 26.4 0.0 0.016 14.8 0.0 3.8 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 CBZ30531.1 - 1.4e-05 24.8 0.3 0.17 11.4 0.0 3.3 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.1 CBZ30531.1 - 3.3e-05 24.2 3.6 0.0053 17.0 0.0 5.5 5 1 1 6 6 5 1 AAA domain Zeta_toxin PF06414.7 CBZ30531.1 - 3.7e-05 22.9 0.0 0.19 10.8 0.0 3.8 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 CBZ30531.1 - 0.00015 21.4 0.1 0.24 11.1 0.0 3.9 3 0 0 3 3 3 1 Part of AAA domain ABC_tran PF00005.22 CBZ30531.1 - 0.00019 21.7 10.9 0.0037 17.5 0.0 4.4 5 0 0 5 5 2 2 ABC transporter AAA_10 PF12846.2 CBZ30531.1 - 0.0002 20.9 0.7 0.074 12.4 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain AAA_29 PF13555.1 CBZ30531.1 - 0.00047 19.6 0.0 0.012 15.0 0.0 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain MobB PF03205.9 CBZ30531.1 - 0.0013 18.4 0.1 0.031 13.9 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CBZ30531.1 - 0.0015 18.2 13.4 0.12 12.0 0.0 4.5 5 0 0 5 5 3 2 Archaeal ATPase SRPRB PF09439.5 CBZ30531.1 - 0.0016 17.6 3.1 0.019 14.2 0.0 3.3 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Laminin_II PF06009.7 CBZ30531.1 - 0.0036 17.0 2.7 0.0036 17.0 1.8 4.9 5 0 0 5 5 3 1 Laminin Domain II Mg_chelatase PF01078.16 CBZ30531.1 - 0.0043 16.2 0.1 5.7 6.0 0.0 3.3 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 CBZ30531.1 - 0.0045 16.6 0.1 1.9 8.1 0.0 3.7 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 CBZ30531.1 - 0.0065 16.0 0.0 18 4.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 CBZ30531.1 - 0.011 15.7 0.1 2.6 8.0 0.0 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.1 CBZ30531.1 - 0.012 15.6 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CBZ30531.1 - 0.013 14.9 2.2 1.6 8.1 0.0 3.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Guanylate_kin PF00625.16 CBZ30531.1 - 0.14 11.6 0.0 0.14 11.6 0.0 4.3 5 0 0 5 5 3 0 Guanylate kinase SMC_N PF02463.14 CBZ30531.1 - 0.42 9.8 0.0 22 4.2 0.0 3.0 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CBZ30531.1 - 2.9 8.1 0.0 2.9 8.1 0.0 7.5 8 0 0 8 8 6 0 AAA domain Reo_sigmaC PF04582.7 CBZ30531.1 - 4.1 6.5 7.9 12 4.9 0.5 3.7 3 0 0 3 3 3 0 Reovirus sigma C capsid protein zf-CCHC_3 PF13917.1 CBZ30532.1 - 4.2e-14 51.9 1.3 8e-14 51.0 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.3 CBZ30532.1 - 0.00055 19.8 0.6 0.00055 19.8 0.4 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G DUF1193 PF06702.7 CBZ30533.1 - 1.7e-05 24.3 0.0 3.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1193) Metallophos PF00149.23 CBZ30534.1 - 1.5e-35 122.4 0.0 2e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HTH_Tnp_ISL3 PF13542.1 CBZ30536.1 - 0.097 11.8 0.1 0.28 10.3 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Complex1_LYR PF05347.10 CBZ30537.1 - 0.066 13.0 0.4 0.14 11.9 0.3 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Robl_LC7 PF03259.12 CBZ30538.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Roadblock/LC7 domain BRCT PF00533.21 CBZ30539.1 - 2.8e-08 33.7 0.0 1.2e-05 25.3 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain FHA PF00498.21 CBZ30539.1 - 2.6e-07 30.6 0.0 4.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain PTCB-BRCT PF12738.2 CBZ30539.1 - 2.4e-05 24.0 0.0 5.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Kinesin PF00225.18 CBZ30541.1 - 4.4e-105 351.0 0.1 7.3e-105 350.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Pex24p PF06398.6 CBZ30541.1 - 3.7e-05 22.6 2.6 6.8e-05 21.8 1.8 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Fib_alpha PF08702.5 CBZ30541.1 - 0.21 11.7 6.1 0.4 10.8 3.9 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Cullin_binding PF03556.10 CBZ30542.1 - 1.4e-14 54.2 0.4 2.4e-14 53.4 0.3 1.3 1 0 0 1 1 1 1 Cullin binding Ank_2 PF12796.2 CBZ30543.1 - 2.6e-23 82.1 3.5 6e-11 42.5 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ30543.1 - 1.5e-17 62.4 5.4 8.4e-06 25.3 0.0 5.4 4 1 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 CBZ30543.1 - 6.4e-17 61.5 3.3 5.1e-06 26.8 0.1 4.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ30543.1 - 4e-15 54.4 2.2 0.0031 17.5 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 CBZ30543.1 - 1.7e-13 50.2 13.7 3e-06 27.2 0.1 5.2 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Gar1 PF04410.9 CBZ30544.1 - 1.1e-37 128.8 0.3 1.1e-37 128.8 0.2 2.3 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region zf-DHHC PF01529.15 CBZ30545.1 - 1.8e-14 53.4 4.3 1.8e-14 53.4 3.0 1.9 1 1 0 2 2 2 1 DHHC palmitoyltransferase Cys_knot PF00007.17 CBZ30545.1 - 0.017 15.2 0.8 0.031 14.3 0.6 1.4 1 0 0 1 1 1 0 Cystine-knot domain Coatomer_WDAD PF04053.9 CBZ30546.1 - 6.4e-98 328.4 0.1 9.4e-98 327.8 0.1 1.2 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CBZ30546.1 - 6.1e-88 295.1 0.0 9.1e-88 294.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CBZ30546.1 - 3e-48 160.0 20.9 1e-10 41.0 0.1 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat HSDR_N PF04313.9 CBZ30546.1 - 0.02 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) ESSS PF10183.4 CBZ30547.1 - 1.2e-13 51.3 5.6 1.4e-13 51.1 3.9 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) adh_short PF00106.20 CBZ30548.1 - 1.7e-09 37.8 6.8 5.2e-09 36.2 4.7 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 CBZ30548.1 - 0.00082 18.8 0.1 0.0018 17.7 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CBZ30548.1 - 0.006 15.5 0.2 0.02 13.7 0.1 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Saccharop_dh PF03435.13 CBZ30548.1 - 0.012 14.6 0.4 0.014 14.3 0.3 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 CBZ30548.1 - 0.17 11.8 2.3 0.14 12.1 0.8 1.6 2 0 0 2 2 2 0 NADH(P)-binding Proteasome PF00227.21 CBZ30549.1 - 1.1e-27 96.5 0.0 1.2e-27 96.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.22 CBZ30550.1 - 6.7e-52 176.3 0.2 1.4e-51 175.2 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 CBZ30550.1 - 4.3e-40 137.7 4.3 7.4e-40 137.0 1.3 2.4 2 1 0 2 2 2 1 FAT domain Rapamycin_bind PF08771.6 CBZ30550.1 - 2.1e-31 107.9 0.5 1.1e-30 105.6 0.1 2.5 2 0 0 2 2 2 1 Rapamycin binding domain DUF3385 PF11865.3 CBZ30550.1 - 1.2e-24 87.0 0.0 7.1e-24 84.5 0.0 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) FATC PF02260.15 CBZ30550.1 - 7.1e-12 44.5 0.3 2.7e-11 42.7 0.2 2.1 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 CBZ30550.1 - 0.00087 19.1 10.6 1.1 9.4 0.0 7.3 8 0 0 8 8 8 1 HEAT repeat ADIP PF11559.3 CBZ30551.1 - 0.0011 18.9 5.9 0.0012 18.7 4.1 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Tom22 PF04281.8 CBZ30551.1 - 0.003 17.0 1.7 0.0037 16.7 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 YkyA PF10368.4 CBZ30551.1 - 0.004 16.5 6.0 0.0044 16.3 4.1 1.0 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein Pox_F11 PF04943.7 CBZ30551.1 - 0.0043 15.9 2.1 0.0051 15.7 1.4 1.0 1 0 0 1 1 1 1 Poxvirus F11 protein EIF_2_alpha PF07541.7 CBZ30551.1 - 0.0047 16.6 2.1 0.56 9.9 0.1 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit Rho_Binding PF08912.6 CBZ30551.1 - 0.006 16.8 4.8 0.0078 16.4 0.5 2.5 1 1 2 3 3 3 1 Rho Binding Occludin_ELL PF07303.8 CBZ30551.1 - 0.011 16.4 1.5 0.013 16.1 1.1 1.1 1 0 0 1 1 1 0 Occludin homology domain DUF4061 PF13270.1 CBZ30551.1 - 0.013 15.5 0.9 0.021 14.9 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) IFT57 PF10498.4 CBZ30551.1 - 0.022 13.5 4.0 0.024 13.4 2.7 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Filament PF00038.16 CBZ30551.1 - 0.027 13.9 5.7 0.038 13.4 4.0 1.3 1 0 0 1 1 1 0 Intermediate filament protein CorA PF01544.13 CBZ30551.1 - 0.027 13.4 2.0 0.029 13.4 1.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Apt1 PF10351.4 CBZ30551.1 - 0.037 12.9 4.0 0.039 12.8 2.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain IncA PF04156.9 CBZ30551.1 - 0.063 12.8 7.7 0.08 12.5 5.3 1.2 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 CBZ30551.1 - 0.074 12.2 7.4 0.091 11.9 5.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.1 CBZ30551.1 - 0.075 12.4 7.6 0.16 11.3 5.3 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Sec20 PF03908.8 CBZ30551.1 - 0.1 12.3 2.5 0.68 9.6 1.7 2.1 1 1 0 1 1 1 0 Sec20 CCDC144C PF14915.1 CBZ30551.1 - 0.11 11.3 7.6 0.13 11.1 5.2 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF2422 PF10337.4 CBZ30551.1 - 0.17 10.6 2.6 0.19 10.4 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) AAA_13 PF13166.1 CBZ30551.1 - 0.17 10.2 3.9 0.21 10.0 2.7 1.2 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 CBZ30551.1 - 0.22 9.3 3.0 0.25 9.1 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIVA PF05103.8 CBZ30551.1 - 0.26 11.3 6.5 0.13 12.2 1.5 2.3 1 1 0 1 1 1 0 DivIVA protein DUF1366 PF07104.6 CBZ30551.1 - 0.32 10.6 4.3 1.2 8.7 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1366) Reo_sigmaC PF04582.7 CBZ30551.1 - 0.53 9.4 3.3 0.57 9.3 2.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Cluap1 PF10234.4 CBZ30551.1 - 0.54 9.4 8.3 1.4 8.0 5.7 1.6 1 1 0 1 1 1 0 Clusterin-associated protein-1 DivIC PF04977.10 CBZ30551.1 - 0.58 9.6 10.9 0.24 10.8 0.3 2.9 1 1 2 3 3 3 0 Septum formation initiator PspB PF06667.7 CBZ30551.1 - 0.62 10.0 4.2 4.2 7.3 0.2 2.5 1 1 1 2 2 2 0 Phage shock protein B DUF1151 PF06625.6 CBZ30551.1 - 0.64 9.7 4.7 0.75 9.5 2.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1151) Atg14 PF10186.4 CBZ30551.1 - 0.73 8.7 4.4 0.8 8.5 3.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med9 PF07544.8 CBZ30551.1 - 1.1 9.0 5.0 0.88 9.3 1.4 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FliD_N PF02465.13 CBZ30551.1 - 1.1 9.6 6.9 5.1 7.5 4.8 1.9 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus APG6 PF04111.7 CBZ30551.1 - 1.2 8.0 6.8 1.4 7.9 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Prefoldin_2 PF01920.15 CBZ30551.1 - 1.6 8.5 9.4 0.89 9.3 3.3 2.2 1 1 1 2 2 2 0 Prefoldin subunit NuA4 PF09340.5 CBZ30551.1 - 1.9 8.2 4.3 16 5.1 0.1 2.2 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 TPR_MLP1_2 PF07926.7 CBZ30551.1 - 2.7 7.7 10.3 5.3 6.7 1.4 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-Q PF13094.1 CBZ30551.1 - 4.1 7.3 9.7 9.2 6.2 6.7 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Seryl_tRNA_N PF02403.17 CBZ30551.1 - 4.5 7.3 8.6 1.2 9.1 2.6 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Rcd1 PF04078.8 CBZ30552.1 - 9.7e-108 358.9 0.4 1.1e-107 358.7 0.3 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like RRM_1 PF00076.17 CBZ30553.1 - 1.1e-29 101.7 0.0 1.5e-14 53.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ30553.1 - 1.8e-25 88.6 0.0 4.6e-14 52.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ30553.1 - 3.3e-09 36.4 0.1 0.0024 17.6 0.0 3.9 3 2 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CBZ30553.1 - 0.0026 17.4 0.0 0.11 12.2 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CBZ30553.1 - 0.0035 17.1 0.0 9.1 6.1 0.0 3.3 3 0 0 3 3 3 1 RNA binding motif RNA_bind PF08675.6 CBZ30553.1 - 0.0051 16.7 0.1 0.44 10.5 0.0 2.6 2 1 0 2 2 2 1 RNA binding domain FAM176 PF14851.1 CBZ30554.1 - 0.06 13.0 1.4 0.06 13.0 0.9 1.4 2 0 0 2 2 2 0 FAM176 family Tmemb_170 PF10190.4 CBZ30554.1 - 0.22 11.6 5.1 0.29 11.2 3.5 1.1 1 0 0 1 1 1 0 Putative transmembrane protein 170 MBOAT_2 PF13813.1 CBZ30554.1 - 0.35 10.9 3.7 1.1 9.3 2.2 1.9 1 1 1 2 2 2 0 Membrane bound O-acyl transferase family VIT1 PF01988.14 CBZ30554.1 - 4.7 6.6 7.3 10 5.5 5.1 1.5 1 1 0 1 1 1 0 VIT family WD40 PF00400.27 CBZ30555.1 - 2.6e-13 49.2 9.0 0.00038 20.2 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat APS_kinase PF01583.15 CBZ30556.1 - 0.069 12.8 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 Adenylylsulphate kinase Myb_DNA-bind_6 PF13921.1 CBZ30556.1 - 0.11 12.5 0.1 2.4 8.3 0.0 2.5 1 1 1 2 2 2 0 Myb-like DNA-binding domain ARD PF03079.9 CBZ30557.1 - 2.4e-27 95.8 0.1 2.4e-27 95.8 0.0 2.1 2 0 0 2 2 2 1 ARD/ARD' family Cupin_2 PF07883.6 CBZ30557.1 - 1e-06 28.1 0.0 4e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 CBZ30557.1 - 0.00024 20.7 0.0 0.00044 19.9 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 CBZ30557.1 - 0.0015 17.9 0.0 0.0037 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 CBZ30557.1 - 0.0024 17.4 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.17 CBZ30557.1 - 0.0033 16.8 0.0 0.0067 15.8 0.0 1.5 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 CBZ30557.1 - 0.011 15.2 2.2 0.024 14.1 0.0 2.1 2 1 0 2 2 2 0 Cupin-like domain Ehbp PF10622.4 CBZ30557.1 - 0.067 13.1 0.3 1 9.3 0.0 2.8 1 1 2 3 3 3 0 Energy-converting hydrogenase B subunit P (EhbP) AAA_18 PF13238.1 CBZ30557.1 - 0.1 12.8 0.3 0.1 12.8 0.2 2.6 2 1 0 2 2 1 0 AAA domain 2OG-FeII_Oxy_5 PF13759.1 CBZ30557.1 - 0.11 12.7 0.2 0.31 11.3 0.0 1.8 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Ycf1 PF05758.7 CBZ30557.1 - 0.41 8.3 5.9 0.51 8.0 4.1 1.2 1 0 0 1 1 1 0 Ycf1 PhyH PF05721.8 CBZ30557.1 - 0.49 10.3 2.4 3.3 7.6 0.0 2.5 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) OmpH PF03938.9 CBZ30557.1 - 2.7 7.8 9.7 4.9 7.0 6.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YqfQ PF14181.1 CBZ30557.1 - 6.8 6.7 6.8 12 5.9 4.7 1.4 1 0 0 1 1 1 0 YqfQ-like protein DUF3340 PF11818.3 CBZ30557.1 - 8.1 6.3 16.6 14 5.6 11.3 1.7 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) cNMP_binding PF00027.24 CBZ30559.1 - 6.3e-10 38.7 0.0 2.1e-09 37.0 0.0 2.0 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PK PF00224.16 CBZ30560.1 - 1.1e-95 320.2 0.2 1.2e-95 320.0 0.1 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain HpcH_HpaI PF03328.9 CBZ30560.1 - 0.0041 16.0 0.0 0.0075 15.1 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 CBZ30561.1 - 9.8e-144 478.2 0.4 1.4e-143 477.6 0.3 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CBZ30561.1 - 1.2e-24 86.0 2.4 1.5e-24 85.7 0.1 2.3 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CBZ30561.1 - 0.0002 20.3 1.0 0.00085 18.2 0.6 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PI-PLC-X PF00388.14 CBZ30562.1 - 6.9e-56 187.7 0.0 1.2e-55 186.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CBZ30562.1 - 5.2e-34 116.7 0.0 1.2e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 CBZ30562.1 - 4e-06 26.7 0.7 0.00089 19.2 0.0 2.7 2 1 1 3 3 3 2 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 CBZ30562.1 - 0.004 16.3 0.4 0.014 14.6 0.3 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 CBZ30562.1 - 0.0078 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair Transket_pyr PF02779.19 CBZ30563.1 - 5e-41 140.1 0.0 8.6e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CBZ30563.1 - 7.2e-35 119.6 0.0 1.7e-34 118.4 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain Shal-type PF11601.3 CBZ30563.1 - 0.083 12.4 0.7 0.17 11.4 0.5 1.5 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels AAA PF00004.24 CBZ30564.1 - 0.026 14.7 0.1 0.095 12.9 0.1 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CBZ30564.1 - 8.6 6.5 8.0 3 7.9 2.6 2.4 1 1 1 3 3 3 0 AAA domain Band_7 PF01145.20 CBZ30565.1 - 5.9e-27 94.7 1.5 9.4e-27 94.0 1.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family TrkH PF02386.11 CBZ30566.1 - 3.4e-16 58.7 22.6 2.4e-09 36.2 1.4 3.9 2 2 1 3 3 3 3 Cation transport protein Ribosomal_S7 PF00177.16 CBZ30567.1 - 0.053 13.0 0.4 0.12 11.9 0.2 1.6 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e DUF1456 PF07308.8 CBZ30567.1 - 0.066 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) UCR_14kD PF02271.11 CBZ30568.1 - 1.1e-08 34.7 0.0 2.8e-08 33.4 0.0 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit BIR PF00653.16 CBZ30568.1 - 0.034 14.5 0.3 0.068 13.6 0.2 1.5 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain Clat_adaptor_s PF01217.15 CBZ30569.1 - 4.3e-10 39.4 0.0 6.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain LMBR1 PF04791.11 CBZ30570.1 - 8.4e-16 57.5 31.8 1.8e-10 40.0 5.1 2.8 1 1 0 2 2 2 2 LMBR1-like membrane protein CTV_P33 PF07184.6 CBZ30570.1 - 0.27 10.0 0.0 0.27 10.0 0.0 2.2 3 0 0 3 3 3 0 Citrus tristeza virus P33 protein Arf PF00025.16 CBZ30571.1 - 3.6e-65 218.4 0.1 4.1e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CBZ30571.1 - 7.7e-13 47.8 2.0 1.5e-07 30.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CBZ30571.1 - 4.5e-10 39.0 0.0 5.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CBZ30571.1 - 1.5e-08 34.1 0.0 1.8e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CBZ30571.1 - 1.5e-07 30.8 0.0 1.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CBZ30571.1 - 2.4e-06 27.1 0.0 2.6e-05 23.7 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CBZ30571.1 - 3.6e-06 27.4 0.0 4.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CBZ30571.1 - 9.3e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ30571.1 - 0.0042 16.3 0.1 0.015 14.5 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Mito_carr PF00153.22 CBZ30573.1 - 1e-07 31.5 1.7 0.0025 17.4 0.1 3.0 2 1 1 3 3 3 2 Mitochondrial carrier protein DUF2157 PF09925.4 CBZ30573.1 - 7.9 6.0 11.3 0.096 12.2 0.5 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) UPF0184 PF03670.8 CBZ30575.1 - 0.13 12.4 1.5 0.39 10.9 0.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) eIF-4B PF06273.6 CBZ30575.1 - 0.18 10.5 3.6 0.26 10.0 2.5 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF4407 PF14362.1 CBZ30575.1 - 0.18 10.7 5.3 0.31 9.9 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DIT1_PvcA PF05141.7 CBZ30575.1 - 0.79 8.9 5.6 0.1 11.9 0.9 1.7 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein V_ATPase_I PF01496.14 CBZ30575.1 - 1.1 7.0 4.2 0.53 8.0 0.6 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S46 PF10459.4 CBZ30575.1 - 1.7 6.9 6.7 2.7 6.3 4.7 1.2 1 0 0 1 1 1 0 Peptidase S46 Tropomyosin_1 PF12718.2 CBZ30575.1 - 5.4 6.8 20.0 0.035 13.9 4.5 2.9 2 1 1 3 3 3 0 Tropomyosin like Macoilin PF09726.4 CBZ30575.1 - 6.8 4.8 10.8 9.2 4.4 7.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Reo_sigmaC PF04582.7 CBZ30576.1 - 0.00043 19.5 57.4 0.0072 15.5 3.0 6.5 3 2 4 7 7 7 3 Reovirus sigma C capsid protein GAS PF13851.1 CBZ30576.1 - 0.0022 17.2 4.3 0.0022 17.2 3.0 8.2 3 2 4 7 7 7 3 Growth-arrest specific micro-tubule binding IncA PF04156.9 CBZ30576.1 - 0.0034 17.0 15.1 0.0034 17.0 10.5 8.1 2 2 5 7 7 7 4 IncA protein FlaC_arch PF05377.6 CBZ30576.1 - 2.8 7.8 40.3 0.69 9.8 0.2 9.9 8 4 5 13 13 13 0 Flagella accessory protein C (FlaC) Myosin_tail_1 PF01576.14 CBZ30576.1 - 4.6 4.8 136.1 84 0.6 36.8 4.6 1 1 1 2 2 2 0 Myosin tail NIF PF03031.13 CBZ30577.1 - 9.4e-33 113.1 0.0 1.3e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.21 CBZ30577.1 - 0.0063 16.9 0.0 0.0082 16.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CBZ30577.1 - 0.013 15.6 0.0 0.033 14.4 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CBZ30577.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF705 PF05152.7 CBZ30577.1 - 0.068 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) SapA PF02199.10 CBZ30577.1 - 0.12 12.1 0.3 0.28 10.9 0.2 1.6 1 0 0 1 1 1 0 Saposin A-type domain DUF1242 PF06842.7 CBZ30579.1 - 1e-11 44.1 0.8 1.5e-11 43.6 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DnaJ PF00226.26 CBZ30581.1 - 2.5e-05 23.9 0.0 0.00016 21.3 0.0 2.2 1 1 0 1 1 1 1 DnaJ domain zf-CCCH PF00642.19 CBZ30581.1 - 0.26 11.0 4.4 0.58 9.8 3.1 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_L7Ae PF01248.21 CBZ30582.1 - 8.6e-25 86.0 0.0 9.7e-25 85.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ArfGap PF01412.13 CBZ30584.1 - 2.2e-28 98.4 0.1 5e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 CBZ30584.1 - 0.023 14.8 0.0 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 PH domain DUF3311 PF11755.3 CBZ30585.1 - 0.012 15.0 0.5 0.048 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) AA_permease_2 PF13520.1 CBZ30585.1 - 0.065 11.7 0.2 0.067 11.7 0.1 1.0 1 0 0 1 1 1 0 Amino acid permease 3HCDH PF00725.17 CBZ30587.1 - 9e-10 38.8 0.1 0.0015 18.9 0.0 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Rrf2 PF02082.15 CBZ30587.1 - 0.037 14.1 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator Ank_2 PF12796.2 CBZ30589.1 - 1e-13 51.3 0.0 6.5e-12 45.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ30589.1 - 8.5e-13 47.4 0.1 0.00041 20.0 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 CBZ30589.1 - 5.5e-09 35.3 0.1 0.034 14.3 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 CBZ30589.1 - 7.7e-08 32.3 0.1 6.6e-05 23.0 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CBZ30589.1 - 5.8e-07 29.8 0.0 0.0062 17.0 0.0 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Aminotran_1_2 PF00155.16 CBZ30590.1 - 2.6e-46 158.2 0.0 3.1e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CBZ30590.1 - 0.024 13.7 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CBZ30590.1 - 0.075 12.0 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family adh_short PF00106.20 CBZ30591.1 - 2.5e-29 102.3 2.3 4.9e-29 101.3 1.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBZ30591.1 - 7.1e-16 58.3 1.9 7.1e-16 58.3 1.3 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 CBZ30591.1 - 4e-12 46.4 0.1 5.2e-12 46.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 CBZ30591.1 - 0.0012 17.8 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 CBZ30591.1 - 0.0081 15.6 0.1 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 CBZ30591.1 - 0.014 15.1 0.1 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_tranf_2_3 PF13641.1 CBZ30591.1 - 0.021 14.6 0.4 0.032 14.0 0.3 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 7kD_coat PF02495.12 CBZ30591.1 - 0.078 12.4 0.5 0.17 11.3 0.3 1.5 1 0 0 1 1 1 0 7kD viral coat protein ECH PF00378.15 CBZ30594.1 - 4.2e-52 176.7 4.0 3.4e-51 173.7 2.8 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DEAD PF00270.24 CBZ30595.1 - 2e-43 147.8 0.5 2.9e-43 147.3 0.4 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ30595.1 - 5e-25 87.1 0.3 1.1e-24 86.0 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CBZ30595.1 - 0.011 15.8 0.4 0.037 14.1 0.3 1.9 1 1 0 1 1 1 0 AAA domain End3 PF12761.2 CBZ30595.1 - 0.092 12.3 0.1 4.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 AAA PF00004.24 CBZ30595.1 - 0.12 12.5 1.0 1.9 8.6 0.7 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thioredoxin PF00085.15 CBZ30596.1 - 8.8e-06 25.3 0.0 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CBZ30596.1 - 9.7e-05 22.4 0.1 0.014 15.5 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CBZ30596.1 - 0.01 15.8 0.1 0.029 14.3 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.1 CBZ30596.1 - 0.024 14.2 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.1 CBZ30596.1 - 0.14 12.3 0.0 0.91 9.7 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain Ribosomal_S3Ae PF01015.13 CBZ30598.1 - 1.5e-61 207.1 4.6 1.7e-61 206.9 3.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family TMEM156 PF15106.1 CBZ30598.1 - 0.032 13.4 0.1 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 TMEM156 protein family DNA_pol3_delt_C PF14840.1 CBZ30598.1 - 0.068 13.2 2.4 0.11 12.6 1.4 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term SHIPPO-rpt PF07004.7 CBZ30599.1 - 6.3e-16 58.3 26.2 0.0076 17.1 0.0 9.7 8 1 0 8 8 8 8 Sperm-tail PG-rich repeat Arrestin_N PF00339.24 CBZ30600.1 - 3.1e-07 30.3 0.0 7.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.24 CBZ30601.1 - 3.9e-05 23.5 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain dsrm PF00035.20 CBZ30601.1 - 0.18 12.3 2.8 0.98 10.0 0.0 2.9 3 0 0 3 3 3 0 Double-stranded RNA binding motif HAP2-GCS1 PF10699.4 CBZ30602.1 - 5.1e-21 74.3 0.2 2.2e-20 72.3 0.0 2.1 2 0 0 2 2 2 1 Male gamete fusion factor DUF3737 PF12541.3 CBZ30602.1 - 0.06 12.3 0.0 7 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3737) Pkinase PF00069.20 CBZ30605.1 - 5.6e-52 176.4 0.1 9.1e-32 110.2 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30605.1 - 8.8e-25 87.2 0.2 7.2e-19 67.8 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase EF-hand_6 PF13405.1 CBZ30605.1 - 1.3e-07 30.8 0.0 0.013 15.3 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 CBZ30605.1 - 3e-05 24.0 0.2 0.26 11.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair Kinase-like PF14531.1 CBZ30605.1 - 0.00033 19.7 0.0 0.63 8.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like EF-hand_1 PF00036.27 CBZ30605.1 - 0.00039 19.5 0.0 0.21 10.9 0.0 3.0 3 0 0 3 3 3 2 EF hand SNAPc_SNAP43 PF09808.4 CBZ30605.1 - 0.071 12.7 0.7 0.18 11.4 0.5 1.6 1 1 0 1 1 1 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Kdo PF06293.9 CBZ30605.1 - 0.15 11.0 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.2 CBZ30606.1 - 2.3e-16 58.9 17.4 4.2e-06 26.2 1.3 6.2 2 2 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ30606.1 - 1.9e-12 46.7 18.3 0.00065 19.4 0.2 5.0 4 2 1 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 CBZ30606.1 - 3.9e-07 29.1 13.3 6.8 7.1 0.0 8.7 9 0 0 9 9 9 2 Leucine Rich Repeat Mit_proteolip PF08039.6 CBZ30606.1 - 0.02 14.8 0.0 5 7.1 0.0 5.5 1 0 0 1 1 1 0 Mitochondrial proteolipid DUF3079 PF11278.3 CBZ30606.1 - 0.13 11.8 2.4 0.6 9.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) LRR_7 PF13504.1 CBZ30606.1 - 0.46 10.8 17.5 9 6.9 0.1 7.4 6 2 1 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 CBZ30606.1 - 0.9 9.8 12.2 56 4.2 0.0 6.8 7 0 0 7 7 7 0 Leucine Rich repeat LRR_4 PF12799.2 CBZ30607.1 - 4.3e-11 42.1 6.6 5e-05 22.8 0.9 5.4 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ30607.1 - 8.8e-08 31.7 10.4 0.00013 21.6 2.9 4.4 3 1 2 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 CBZ30607.1 - 2.1e-07 30.0 1.3 5.3 7.4 0.1 6.7 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ30607.1 - 0.33 11.3 8.3 7.2 7.2 0.1 4.9 5 0 0 5 5 5 0 Leucine rich repeat PIP5K PF01504.13 CBZ30608.1 - 7.6e-60 202.1 0.0 1.2e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WD40 PF00400.27 CBZ30609.1 - 1.4e-11 43.8 26.0 5e-05 23.0 1.3 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat Snf7 PF03357.16 CBZ30610.1 - 8.4e-38 129.4 18.3 9.8e-38 129.2 12.7 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 CBZ30610.1 - 0.017 15.3 1.6 0.017 15.3 1.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2031 PF09592.5 CBZ30610.1 - 0.22 10.6 3.6 0.22 10.6 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2031) Astro_capsid PF03115.9 CBZ30610.1 - 0.66 8.1 5.7 0.81 7.8 4.0 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor IncA PF04156.9 CBZ30610.1 - 0.97 8.9 12.8 0.19 11.3 1.7 2.0 1 1 1 2 2 2 0 IncA protein Phage_Gp23 PF10669.4 CBZ30610.1 - 3 7.9 10.5 1.8 8.6 5.8 1.8 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) Sulfate_transp PF00916.15 CBZ30611.1 - 0.094 11.7 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Sulfate transporter family Ribosomal_L18ae PF01775.12 CBZ30612.1 - 5.5e-41 139.3 1.4 7.6e-41 138.8 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Nup35_RRM_2 PF14605.1 CBZ30615.1 - 1.1e-14 53.9 0.0 1.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Glyco_hydro_32N PF00251.15 CBZ30616.1 - 3.1e-59 200.8 5.9 5.6e-58 196.7 3.4 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CBZ30616.1 - 1.5e-07 31.6 0.0 2.3e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal PAN_4 PF14295.1 CBZ30616.1 - 0.00012 21.7 1.8 0.00042 19.9 1.3 2.0 1 0 0 1 1 1 1 PAN domain Phosphoprotein PF00922.12 CBZ30616.1 - 1.1 8.4 3.3 2.2 7.4 2.3 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein TALPID3 PF15324.1 CBZ30616.1 - 1.2 6.4 3.8 1.7 5.8 2.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target zf-RING_2 PF13639.1 CBZ30617.1 - 0.0036 17.0 9.6 0.0036 17.0 6.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 CBZ30617.1 - 0.031 14.0 8.3 0.017 14.8 3.5 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CBZ30617.1 - 0.071 12.8 3.7 0.17 11.6 2.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CBZ30617.1 - 0.45 10.5 16.4 0.041 13.9 6.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ30617.1 - 0.48 10.2 13.4 0.052 13.2 5.9 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CBZ30617.1 - 0.52 10.0 14.0 0.068 12.8 6.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CBZ30617.1 - 7.1 6.5 14.2 0.1 12.4 4.7 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING TPR_12 PF13424.1 CBZ30620.1 - 6.3e-69 227.9 34.6 1.3e-14 53.8 1.0 8.1 6 2 2 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ30620.1 - 3.4e-40 134.8 23.9 3.3e-06 26.8 0.1 11.4 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ30620.1 - 3.1e-29 100.4 38.6 2.9e-07 30.0 0.1 8.1 6 3 2 9 9 9 7 TPR repeat TPR_2 PF07719.12 CBZ30620.1 - 1.3e-21 74.7 42.5 0.0043 16.8 0.1 12.4 12 1 0 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ30620.1 - 1.8e-19 68.4 43.4 4.1e-05 23.0 0.0 12.4 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ30620.1 - 1.2e-16 60.8 29.1 0.0011 19.5 0.3 8.4 7 2 1 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ30620.1 - 1e-15 56.2 31.8 0.02 14.6 0.0 11.1 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ30620.1 - 2.6e-14 51.7 23.8 0.0027 17.3 0.0 10.2 10 1 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ30620.1 - 8.3e-13 47.7 29.0 0.59 10.9 0.0 11.5 8 2 4 12 12 12 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ30620.1 - 9.3e-09 35.3 32.3 0.00014 21.9 1.6 6.1 3 1 4 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 CBZ30620.1 - 4.2e-05 23.8 26.2 0.077 13.3 0.3 7.5 6 1 3 9 9 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 CBZ30620.1 - 0.01 15.0 0.0 19 4.6 0.0 4.3 3 0 0 3 3 3 0 SHNi-TPR Apc5 PF12862.2 CBZ30620.1 - 0.018 14.8 14.4 2.7 7.8 0.3 6.1 4 2 1 5 5 5 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.1 CBZ30620.1 - 1.2 9.5 18.1 23 5.4 0.0 7.7 8 1 0 8 8 7 0 Tetratricopeptide repeat DUF3856 PF12968.2 CBZ30620.1 - 8.7 6.1 9.0 2.3 8.0 1.3 3.3 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) ATP-synt_D PF01813.12 CBZ30621.1 - 6.1e-75 251.0 0.7 9.2e-75 250.5 0.5 1.3 1 0 0 1 1 1 1 ATP synthase subunit D DUF885 PF05960.6 CBZ30621.1 - 0.0035 16.5 2.5 0.0045 16.2 1.8 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Exo_endo_phos PF03372.18 CBZ30622.1 - 1.9e-09 37.8 0.0 5.2e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SET PF00856.23 CBZ30624.1 - 1.2e-10 41.9 1.4 0.0069 16.7 0.0 3.6 2 1 1 3 3 3 3 SET domain TMEM154 PF15102.1 CBZ30624.1 - 0.13 11.9 0.2 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family FHA PF00498.21 CBZ30625.1 - 0.0013 18.7 0.1 0.005 16.9 0.0 2.0 2 0 0 2 2 2 1 FHA domain PA28_beta PF02252.13 CBZ30626.1 - 3.1e-06 26.7 0.1 0.0015 17.9 0.0 2.3 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit Toxin_40 PF15520.1 CBZ30626.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 40 CBS PF00571.23 CBZ30627.1 - 2.8e-16 59.0 0.7 9.8e-05 22.0 0.0 4.3 4 0 0 4 4 4 4 CBS domain RrnaAD PF00398.15 CBZ30628.1 - 3e-28 98.5 0.0 2.3e-27 95.6 0.0 1.9 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 CBZ30628.1 - 0.00021 21.6 0.0 0.00051 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 CBZ30628.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 SlyX PF04102.7 CBZ30629.1 - 0.018 15.4 1.7 0.018 15.4 1.2 4.8 5 1 0 5 5 5 0 SlyX DUF641 PF04859.7 CBZ30629.1 - 6.4 6.5 11.8 3.4 7.4 1.1 3.4 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Actin PF00022.14 CBZ30630.1 - 6.6e-59 199.2 0.0 4.7e-48 163.5 0.0 2.0 2 0 0 2 2 2 2 Actin Aminotran_1_2 PF00155.16 CBZ30633.1 - 7.1e-68 229.1 0.0 8e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FYVE_2 PF02318.11 CBZ30633.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger FAD_binding_2 PF00890.19 CBZ30634.1 - 3.9e-82 276.3 0.0 5.8e-82 275.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.10 CBZ30634.1 - 1.7e-55 188.1 0.1 3.4e-55 187.0 0.0 1.5 1 0 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.16 CBZ30634.1 - 4.9e-17 62.4 0.0 1.1e-16 61.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DAO PF01266.19 CBZ30634.1 - 1.2e-10 40.8 1.9 8.4e-10 38.0 1.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CBZ30634.1 - 1.7e-10 40.5 3.4 4e-10 39.3 2.4 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_6 PF00970.19 CBZ30634.1 - 2.1e-09 37.3 0.0 4.8e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Pyr_redox_2 PF07992.9 CBZ30634.1 - 1.3e-08 34.9 0.1 5.1e-06 26.5 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CBZ30634.1 - 3.2e-07 30.2 0.7 1.7e-06 27.9 0.5 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CBZ30634.1 - 7.2e-06 25.1 4.8 4e-05 22.6 1.9 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 CBZ30634.1 - 0.0004 20.0 0.4 0.0012 18.4 0.3 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 CBZ30634.1 - 0.00041 18.9 4.3 0.0008 17.9 1.4 2.4 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.1 CBZ30634.1 - 0.00077 19.5 0.2 0.056 13.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_6 PF08030.7 CBZ30634.1 - 0.0016 18.3 0.0 0.025 14.4 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox PF00070.22 CBZ30634.1 - 0.0017 18.7 0.9 0.0044 17.4 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CBZ30634.1 - 0.18 10.7 1.1 0.4 9.5 0.8 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2838 PF10998.3 CBZ30636.1 - 3.8e-13 49.2 9.8 1.3e-10 41.1 4.1 3.9 4 1 0 4 4 4 2 Protein of unknown function (DUF2838) Tap-RNA_bind PF09162.5 CBZ30636.1 - 0.14 11.7 0.8 0.37 10.4 0.6 1.6 1 0 0 1 1 1 0 Tap, RNA-binding PBP1_TM PF14812.1 CBZ30637.1 - 0.52 10.6 2.3 1.1 9.6 1.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Telomere_reg-2 PF10193.4 CBZ30638.1 - 0.00059 20.0 0.0 0.21 11.8 0.0 2.9 2 0 0 2 2 2 2 Telomere length regulation protein COX6B PF02297.12 CBZ30640.1 - 0.011 15.6 0.1 0.23 11.5 0.0 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb DUF2805 PF10985.3 CBZ30644.1 - 0.053 13.4 0.4 0.081 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) DUF2207 PF09972.4 CBZ30644.1 - 0.12 10.9 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4355 PF14265.1 CBZ30644.1 - 0.59 10.0 6.3 1 9.3 4.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) PSP1 PF04468.7 CBZ30646.1 - 5.1e-27 93.6 0.3 1.3e-26 92.3 0.2 1.7 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Aldose_epim PF01263.15 CBZ30648.1 - 1.1e-40 139.6 0.0 1.3e-40 139.4 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Aldose_epim PF01263.15 CBZ30649.1 - 5.7e-48 163.5 0.0 6.4e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF45 PF01863.12 CBZ30650.1 - 2.7 7.7 4.6 0.63 9.7 0.1 2.1 2 1 1 3 3 3 0 Protein of unknown function DUF45 Pkinase PF00069.20 CBZ30651.1 - 2.1e-31 109.0 0.0 2.4e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30651.1 - 6.9e-11 41.7 0.0 8.1e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ30651.1 - 4.9e-07 29.7 0.0 0.00062 19.5 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 CBZ30651.1 - 0.0037 16.3 0.1 0.0063 15.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBZ30651.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 CBZ30652.1 - 2.1e-35 122.1 0.0 2.5e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30652.1 - 3.9e-13 49.0 0.0 5.1e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ30652.1 - 0.00015 21.6 0.0 0.00044 20.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CBZ30652.1 - 0.0068 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBZ30652.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-CCCH PF00642.19 CBZ30653.1 - 9.3e-06 25.1 6.2 1.5e-05 24.5 4.3 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cupin_5 PF06172.6 CBZ30654.1 - 4.2e-39 133.6 0.0 6.5e-26 90.8 0.0 2.1 2 0 0 2 2 2 2 Cupin superfamily (DUF985) zf-CCCH PF00642.19 CBZ30655.1 - 3.5e-07 29.7 1.0 6.6e-07 28.8 0.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Zip PF02535.17 CBZ30655.1 - 0.18 10.7 11.3 0.25 10.2 7.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Innate_immun PF12782.2 CBZ30655.1 - 4.8 6.3 17.6 7.4 5.6 12.2 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Pkinase PF00069.20 CBZ30656.1 - 6.4e-65 218.8 0.0 1e-64 218.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30656.1 - 1.9e-22 79.6 0.1 1.1e-21 77.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ30656.1 - 3.6e-05 22.8 0.1 0.06 12.2 0.1 2.9 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 CBZ30656.1 - 0.0037 16.3 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CAF-1_p150 PF11600.3 CBZ30658.1 - 0.00091 18.6 2.0 0.0013 18.1 1.4 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nucleoplasmin PF03066.10 CBZ30658.1 - 0.18 11.3 3.6 0.34 10.4 2.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin Pox_RNA_Pol_19 PF05320.7 CBZ30658.1 - 0.18 11.5 1.3 0.3 10.8 0.9 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CDC45 PF02724.9 CBZ30658.1 - 0.3 9.0 4.2 0.43 8.5 2.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Kri1_C PF12936.2 CBZ30659.1 - 3.7e-22 78.0 0.1 2.1e-21 75.6 0.0 2.3 1 0 0 1 1 1 1 KRI1-like family C-terminal Kri1 PF05178.7 CBZ30659.1 - 1.4e-21 76.6 9.5 1.4e-21 76.6 6.6 4.0 4 0 0 4 4 4 1 KRI1-like family Peptidase_M15_3 PF08291.6 CBZ30660.1 - 0.089 12.6 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Peptidase M15 Rdx PF10262.4 CBZ30661.1 - 2.6e-06 27.3 0.2 5.1e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 Rdx family MecA PF05389.7 CBZ30662.1 - 0.013 15.0 2.7 0.017 14.6 1.9 1.1 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Hid1 PF12722.2 CBZ30662.1 - 4.9 4.6 6.8 6.2 4.3 4.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein STT3 PF02516.9 CBZ30663.1 - 1.1e-47 163.1 30.6 6e-45 154.1 20.3 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT PF02366.13 CBZ30663.1 - 1.4e-06 27.8 11.3 1.4e-06 27.8 7.8 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Vma12 PF11712.3 CBZ30663.1 - 1.5 8.5 3.0 30 4.2 2.1 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase STT3 PF02516.9 CBZ30664.1 - 1.8e-48 165.7 23.1 5.2e-46 157.6 14.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit STT3 PF02516.9 CBZ30665.1 - 1.8e-46 159.1 33.2 4.3e-45 154.5 23.0 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit STT3 PF02516.9 CBZ30666.1 - 1.6e-47 162.6 18.2 4.5e-46 157.8 12.6 2.1 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Rhodanese PF00581.15 CBZ30667.1 - 6.3e-10 39.3 0.0 1.3e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain FAD_binding_2 PF00890.19 CBZ30668.1 - 8.1e-85 285.1 0.1 1.2e-84 284.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.10 CBZ30668.1 - 1.3e-64 217.9 0.0 2e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.16 CBZ30668.1 - 3e-17 63.1 0.0 8.6e-17 61.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_oxidored PF12831.2 CBZ30668.1 - 2.7e-12 46.4 1.0 5.9e-12 45.3 0.7 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 CBZ30668.1 - 9.3e-11 41.2 2.1 2.1e-08 33.4 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CBZ30668.1 - 1.6e-08 34.7 1.3 1.3e-06 28.4 0.9 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_6 PF00970.19 CBZ30668.1 - 7.3e-08 32.4 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_8 PF13450.1 CBZ30668.1 - 1.5e-07 31.3 1.7 1e-06 28.6 0.8 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CBZ30668.1 - 4e-07 29.2 5.4 3.6e-06 26.0 1.9 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_6 PF08030.7 CBZ30668.1 - 1.5e-06 28.2 0.0 0.0017 18.3 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HI0933_like PF03486.9 CBZ30668.1 - 1.3e-05 23.8 3.7 0.00014 20.4 1.1 2.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 CBZ30668.1 - 3.6e-05 24.0 2.1 8.9e-05 22.8 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 CBZ30668.1 - 0.0022 17.6 0.2 0.0054 16.3 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 CBZ30668.1 - 0.0026 16.7 1.5 0.011 14.6 0.5 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 CBZ30668.1 - 0.0038 17.3 3.7 0.6 10.1 0.3 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CBZ30668.1 - 0.0045 16.0 0.3 0.0074 15.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CBZ30668.1 - 0.0059 15.7 0.4 0.024 13.7 0.3 2.0 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 CBZ30669.1 - 3.7e-90 302.7 0.6 4.2e-90 302.5 0.4 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CBZ30669.1 - 8e-10 38.9 0.8 6.8e-06 26.1 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CBZ30669.1 - 3.8e-09 35.9 3.7 2.3e-07 30.0 1.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CBZ30669.1 - 2.3e-08 33.5 5.6 2.8e-08 33.2 2.8 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CBZ30669.1 - 4.2e-08 33.1 1.0 1.5e-07 31.3 0.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CBZ30669.1 - 9.1e-07 29.1 0.2 0.0049 16.9 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CBZ30669.1 - 0.00019 20.4 10.2 0.00038 19.4 1.9 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 CBZ30669.1 - 0.00066 18.2 8.1 0.0046 15.4 0.8 3.2 3 0 0 3 3 3 2 HI0933-like protein AlaDh_PNT_C PF01262.16 CBZ30669.1 - 0.0043 16.6 0.4 0.0085 15.6 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 CBZ30669.1 - 0.013 14.5 1.8 0.02 13.9 1.2 1.4 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 CBZ30669.1 - 0.019 15.3 1.0 0.053 13.9 0.7 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CBZ30669.1 - 0.033 13.0 0.9 0.16 10.8 0.3 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 CBZ30669.1 - 0.082 12.6 0.9 7.8 6.2 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 CBZ30669.1 - 0.14 11.2 3.8 0.048 12.7 0.7 1.6 2 0 0 2 2 2 0 Thi4 family HA2 PF04408.18 CBZ30670.1 - 3.6e-22 78.2 0.0 7.6e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CBZ30670.1 - 9.9e-18 64.0 0.0 2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CBZ30670.1 - 8e-15 54.4 0.0 2.3e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ30670.1 - 4.9e-09 35.8 0.1 1.5e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ30670.1 - 1.8e-06 28.1 0.0 4.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CBZ30670.1 - 0.00049 19.1 0.0 0.00094 18.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 CBZ30670.1 - 0.0054 17.0 0.1 0.11 12.7 0.1 2.4 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 CBZ30670.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 CBZ30670.1 - 0.017 14.9 0.0 7.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 CBZ30670.1 - 0.043 13.8 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain SRP54 PF00448.17 CBZ30670.1 - 0.045 13.1 0.0 0.12 11.8 0.0 1.8 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 CBZ30670.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBZ30670.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zot PF05707.7 CBZ30670.1 - 0.072 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Sigma54_activat PF00158.21 CBZ30670.1 - 0.13 11.7 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Armet PF10208.4 CBZ30671.1 - 9.1e-09 35.1 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.22 CBZ30671.1 - 7.3e-05 22.1 0.0 0.00017 21.0 0.0 1.6 1 0 0 1 1 1 1 SAP domain DUF4554 PF15091.1 CBZ30671.1 - 0.0049 15.6 0.3 1.4 7.5 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4554) adh_short PF00106.20 CBZ30672.1 - 4.9e-28 98.1 0.1 7.3e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBZ30672.1 - 3.4e-15 56.4 0.3 4.6e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBZ30672.1 - 5.4e-12 45.7 0.0 6.8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CBZ30672.1 - 1.3e-06 28.5 0.1 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBZ30672.1 - 0.0002 20.8 0.2 0.00034 20.1 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 CBZ30672.1 - 0.041 12.7 0.3 0.047 12.5 0.2 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF871 PF05913.6 CBZ30672.1 - 0.047 12.5 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) Saccharop_dh PF03435.13 CBZ30672.1 - 0.06 12.3 0.1 0.07 12.0 0.1 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 CBZ30672.1 - 0.068 13.1 0.4 0.068 13.1 0.3 1.7 2 0 0 2 2 2 0 TrkA-N domain MucB_RseB PF03888.9 CBZ30672.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 MucB/RseB family adh_short PF00106.20 CBZ30673.1 - 3.8e-20 72.4 0.4 2.2e-19 69.9 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CBZ30673.1 - 4.9e-08 33.0 0.0 6.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CBZ30673.1 - 3.3e-07 30.1 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CBZ30673.1 - 1.8e-06 27.6 0.0 2.4e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CBZ30673.1 - 0.0051 16.8 0.4 0.026 14.5 0.3 1.9 1 1 0 1 1 1 1 NADH(P)-binding TIR-like PF10137.4 CBZ30673.1 - 0.049 13.2 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Methyltransf_15 PF09445.5 CBZ30673.1 - 0.077 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase HTH_Tnp_Tc3_1 PF11427.3 CBZ30674.1 - 0.037 13.6 0.3 0.32 10.6 0.1 2.8 3 0 0 3 3 3 0 Tc3 transposase HrcA_DNA-bdg PF03444.10 CBZ30674.1 - 0.044 13.2 0.7 0.65 9.4 0.1 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Glutaredoxin PF00462.19 CBZ30675.1 - 3e-17 62.3 0.9 2.8e-12 46.4 0.0 3.2 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.15 CBZ30675.1 - 1.1e-13 50.7 0.0 2.6e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 CBZ30675.1 - 0.00021 21.3 0.0 0.00051 20.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CBZ30675.1 - 0.00053 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CBZ30675.1 - 0.012 15.4 0.1 0.15 11.8 0.1 2.2 2 0 0 2 2 2 0 Thioredoxin domain AhpC-TSA PF00578.16 CBZ30675.1 - 0.02 14.5 0.1 0.029 14.0 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.1 CBZ30675.1 - 0.058 13.5 0.1 0.086 13.0 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain AAA PF00004.24 CBZ30676.1 - 6.2e-36 123.5 0.0 1.4e-35 122.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CBZ30676.1 - 3.5e-08 34.2 0.1 1.7e-07 32.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CBZ30676.1 - 7.8e-08 32.1 0.0 1.9e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CBZ30676.1 - 1.2e-07 31.8 0.1 6.4e-06 26.2 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CBZ30676.1 - 6.8e-07 28.5 0.0 1.9e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CBZ30676.1 - 1.3e-06 28.5 0.0 0.00034 20.7 0.0 2.6 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 CBZ30676.1 - 1.9e-06 26.8 0.0 8.4e-06 24.7 0.0 2.0 1 1 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 CBZ30676.1 - 7.1e-06 25.9 0.0 1.6e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CBZ30676.1 - 1.6e-05 25.1 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ30676.1 - 6.1e-05 22.2 0.0 0.00015 20.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 CBZ30676.1 - 0.00011 22.0 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CBZ30676.1 - 0.00018 20.9 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein SKI PF01202.17 CBZ30676.1 - 0.00027 20.8 0.0 0.0016 18.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_19 PF13245.1 CBZ30676.1 - 0.00027 20.6 0.4 0.0021 17.7 0.3 2.4 1 1 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 CBZ30676.1 - 0.00036 20.6 0.0 0.00076 19.6 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 CBZ30676.1 - 0.0013 18.6 0.1 0.0035 17.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 CBZ30676.1 - 0.0027 16.9 0.0 0.005 16.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CBZ30676.1 - 0.0033 17.4 0.0 0.01 15.9 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.1 CBZ30676.1 - 0.0039 16.7 0.1 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CBZ30676.1 - 0.0042 16.7 0.0 0.0091 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CBZ30676.1 - 0.0042 16.4 1.1 0.069 12.5 0.1 2.3 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 CBZ30676.1 - 0.0058 16.2 0.0 0.013 15.1 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_2 PF07724.9 CBZ30676.1 - 0.007 16.2 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.21 CBZ30676.1 - 0.0094 15.4 0.0 0.027 13.9 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CBZ30676.1 - 0.018 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 CBZ30676.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 CBZ30676.1 - 0.026 14.0 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CBZ30676.1 - 0.029 13.9 0.0 0.072 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 CBZ30676.1 - 0.029 13.6 0.0 0.057 12.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF815 PF05673.8 CBZ30676.1 - 0.029 13.2 0.0 0.078 11.8 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Rad17 PF03215.10 CBZ30676.1 - 0.044 12.4 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2075 PF09848.4 CBZ30676.1 - 0.051 12.5 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CBZ30676.1 - 0.062 13.5 0.1 1.4 9.2 0.0 2.4 1 1 1 2 2 2 0 ABC transporter PPV_E1_C PF00519.12 CBZ30676.1 - 0.079 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase ResIII PF04851.10 CBZ30676.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AFG1_ATPase PF03969.11 CBZ30676.1 - 0.11 11.2 0.3 0.29 9.9 0.0 1.6 1 1 0 2 2 2 0 AFG1-like ATPase 2OG-FeII_Oxy_2 PF13532.1 CBZ30678.1 - 1.4e-11 44.6 0.0 2.2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 CBZ30678.1 - 4.3e-06 26.9 0.0 6.7e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.21 CBZ30680.1 - 1.7e-53 179.8 0.0 1.9e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CBZ30680.1 - 0.0021 17.9 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 CBZ30680.1 - 0.0039 16.9 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CBZ30680.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 UEV domain Histone PF00125.19 CBZ30681.1 - 1.1e-13 51.1 0.7 1.3e-13 50.8 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CBZ30681.1 - 6.6e-05 22.8 0.8 7.1e-05 22.7 0.0 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CBZ30681.1 - 0.0003 20.6 0.2 0.00048 20.0 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 CBZ30681.1 - 0.00065 19.3 0.0 0.00083 19.0 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 CBZ30681.1 - 0.0016 18.1 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PCP_red PF08369.5 CBZ30681.1 - 0.086 12.7 1.0 0.17 11.7 0.2 2.0 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit FbpA PF05833.6 CBZ30681.1 - 0.086 11.3 0.0 0.1 11.1 0.0 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Thioredoxin PF00085.15 CBZ30683.1 - 4.1e-14 52.1 0.0 1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 CBZ30683.1 - 0.0047 16.7 0.1 3.3 7.4 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CBZ30683.1 - 0.0056 16.8 0.1 0.03 14.5 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CBZ30683.1 - 0.027 14.5 0.0 0.16 12.1 0.0 2.4 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.1 CBZ30683.1 - 0.098 12.6 0.0 0.3 11.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like DUF3094 PF11293.3 CBZ30683.1 - 0.15 11.5 2.4 0.19 11.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) MSP1b PF03429.8 CBZ30683.1 - 0.19 9.5 0.4 0.3 8.9 0.3 1.2 1 0 0 1 1 1 0 Major surface protein 1B zf-CDGSH PF09360.5 CBZ30687.1 - 3.8e-26 90.6 9.6 1.8e-14 53.2 1.4 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Peptidase_M16 PF00675.15 CBZ30688.1 - 1.6e-29 102.5 0.0 2.6e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CBZ30688.1 - 6.6e-16 58.5 0.0 1.8e-15 57.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain OTU PF02338.14 CBZ30689.1 - 1.7e-14 54.4 0.1 3.4e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.13 CBZ30689.1 - 6.5e-06 25.1 1.4 6.5e-06 25.1 1.0 5.1 4 1 1 5 5 5 1 Zn-finger in Ran binding protein and others Peptidase_C65 PF10275.4 CBZ30689.1 - 0.00057 19.3 0.0 0.022 14.1 0.0 2.2 1 1 0 1 1 1 1 Peptidase C65 Otubain RRN7 PF11781.3 CBZ30689.1 - 0.0032 16.9 1.6 0.0032 16.9 1.1 3.8 5 1 1 6 6 6 1 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 CBZ30689.1 - 0.0034 17.1 27.7 0.018 14.8 3.8 3.8 2 1 0 3 3 3 2 Double zinc ribbon zf-tcix PF14952.1 CBZ30689.1 - 0.024 13.9 0.2 0.024 13.9 0.2 3.7 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding zf-ribbon_3 PF13248.1 CBZ30689.1 - 4.5 6.6 21.1 0.2 10.9 0.7 3.6 3 0 0 3 3 3 0 zinc-ribbon domain Auto_anti-p27 PF06677.7 CBZ30689.1 - 6.6 6.5 9.3 20 5.0 0.3 3.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RRM_1 PF00076.17 CBZ30690.1 - 1.6e-06 27.6 0.0 0.064 12.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ30690.1 - 3.6e-05 23.6 0.0 9.4e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ30690.1 - 4e-05 23.3 0.3 0.00027 20.7 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDRGK PF09756.4 CBZ30690.1 - 4.3 6.7 8.1 7.7 5.8 5.6 1.3 1 0 0 1 1 1 0 DDRGK domain tRNA-synt_2b PF00587.20 CBZ30691.1 - 6.2e-43 146.3 0.0 1.1e-42 145.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CBZ30691.1 - 3.2e-17 62.2 0.1 6.2e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 CBZ30691.1 - 1.1e-13 50.8 0.0 2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 CBZ30691.1 - 3.5e-11 42.7 0.0 6.1e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TPR_11 PF13414.1 CBZ30692.1 - 4.2e-26 90.3 11.8 1.3e-11 43.9 0.5 5.0 2 2 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 CBZ30692.1 - 9.6e-24 81.9 4.7 1.3e-06 27.7 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ30692.1 - 4.3e-22 78.2 10.1 2.9e-09 37.3 0.3 4.6 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ30692.1 - 1.1e-20 71.7 9.5 1.7e-05 24.3 0.0 6.9 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ30692.1 - 5.9e-20 69.7 8.3 6.9e-06 25.8 0.4 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ30692.1 - 7.2e-15 54.6 2.1 4.1e-07 29.8 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ30692.1 - 6.3e-14 51.2 19.0 5.2e-05 23.5 0.1 7.5 4 2 5 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ30692.1 - 9.3e-12 45.1 10.7 2.8e-06 27.5 0.2 4.8 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ30692.1 - 5.4e-11 41.4 4.7 0.017 14.8 0.0 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ30692.1 - 1.9e-10 39.7 0.1 0.81 9.6 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ30692.1 - 7.8e-05 22.4 4.1 0.2 11.5 0.1 3.8 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ30692.1 - 0.0004 20.6 14.2 0.88 10.1 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_10 PF13374.1 CBZ30692.1 - 0.00046 20.0 8.3 1.8 8.6 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 CBZ30692.1 - 0.0019 18.3 14.9 1.3 9.1 0.1 5.3 3 1 2 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 CBZ30692.1 - 0.0088 16.1 0.0 0.0088 16.1 0.0 2.8 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CBZ30692.1 - 0.16 11.8 2.2 5.3 7.0 0.1 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Ribosomal_L2_C PF03947.13 CBZ30693.1 - 5.4e-40 136.1 2.2 6.2e-40 136.0 0.8 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBZ30693.1 - 4.6e-13 48.9 0.0 1.5e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C PF03947.13 CBZ30694.1 - 5.4e-40 136.1 2.2 6.2e-40 136.0 0.8 1.6 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CBZ30694.1 - 4.6e-13 48.9 0.0 1.5e-12 47.2 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Fib_alpha PF08702.5 CBZ30695.1 - 0.26 11.4 18.9 0.073 13.1 0.8 5.3 4 1 0 4 4 4 0 Fibrinogen alpha/beta chain family Choline_kinase PF01633.15 CBZ30697.1 - 1.6e-31 109.5 0.1 8.6e-31 107.1 0.1 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CBZ30697.1 - 3.6e-11 43.2 0.0 2.5e-08 33.9 0.0 2.6 2 1 0 2 2 2 2 Phosphotransferase enzyme family Arginase PF00491.16 CBZ30698.1 - 3.1e-73 246.4 0.0 3.6e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Arginase family NIF PF03031.13 CBZ30700.1 - 1.4e-17 63.7 0.0 2.5e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-CCCH PF00642.19 CBZ30700.1 - 3.2e-06 26.6 1.9 6.1e-06 25.7 1.3 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rieske PF00355.21 CBZ30703.1 - 1.7e-15 56.3 0.1 3e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Methyltransf_23 PF13489.1 CBZ30706.1 - 7.7e-18 64.7 0.0 1.1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ30706.1 - 6.2e-13 49.0 0.0 1.2e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ30706.1 - 2.8e-09 36.4 0.0 3.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CBZ30706.1 - 2.6e-07 31.0 0.0 5.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ30706.1 - 1.6e-06 27.7 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ30706.1 - 8.8e-06 25.7 0.0 5.1e-05 23.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ30706.1 - 9.4e-05 22.7 0.0 0.00019 21.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ30706.1 - 0.0055 17.2 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AsnC_trans_reg PF01037.16 CBZ30706.1 - 0.11 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AsnC family MTS PF05175.9 CBZ30706.1 - 0.17 11.2 0.0 0.43 9.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_C14 PF00656.17 CBZ30707.1 - 1.9e-49 168.6 0.0 2.4e-49 168.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain SP_C-Propep PF08999.5 CBZ30708.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Laminin_G_3 PF13385.1 CBZ30711.1 - 8.9e-10 39.0 0.2 2.9e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily EF-hand_7 PF13499.1 CBZ30712.1 - 0.00086 19.3 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ30712.1 - 0.0067 15.6 0.0 0.35 10.2 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 CBZ30712.1 - 0.0069 16.1 0.0 0.56 10.2 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain Herpes_UL35 PF04496.7 CBZ30713.1 - 0.063 13.4 1.1 0.12 12.5 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus UL35 family CAF-1_p150 PF11600.3 CBZ30714.1 - 0.00049 19.5 6.9 0.00049 19.5 4.8 4.5 1 1 3 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cortex-I_coil PF09304.5 CBZ30714.1 - 0.0058 16.6 10.0 0.0058 16.6 6.9 7.0 1 1 3 6 6 6 2 Cortexillin I, coiled coil NYD-SP28_assoc PF14775.1 CBZ30714.1 - 0.079 12.6 0.4 0.079 12.6 0.2 5.2 4 1 1 5 5 5 0 Sperm tail C-terminal domain MutL_C PF08676.6 CBZ30715.1 - 1.6e-26 92.6 0.0 4.1e-26 91.3 0.0 1.7 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 CBZ30715.1 - 2.1e-10 40.0 0.0 3.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 CBZ30715.1 - 4.9e-07 29.4 0.0 1.2e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CBZ30715.1 - 6.2e-07 29.1 1.9 3.4e-06 26.7 0.1 2.7 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase KOW PF00467.24 CBZ30716.1 - 4.2e-07 29.4 0.9 1.1e-06 28.0 0.6 1.9 1 1 0 1 1 1 1 KOW motif LRR_4 PF12799.2 CBZ30718.1 - 1.2e-16 59.9 9.8 6.4e-06 25.6 1.3 5.3 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ30718.1 - 1.7e-11 43.6 15.9 7.1e-06 25.6 1.8 4.4 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 CBZ30718.1 - 1.1e-08 33.9 12.1 0.84 9.9 0.0 7.5 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 CBZ30718.1 - 1.5e-06 27.4 14.8 0.27 11.5 0.1 7.6 7 0 0 7 7 7 1 Leucine rich repeat LRR_6 PF13516.1 CBZ30718.1 - 0.0001 21.9 13.5 2.3 8.5 0.1 7.1 5 2 2 7 7 7 2 Leucine Rich repeat IncA PF04156.9 CBZ30718.1 - 0.012 15.1 14.9 0.023 14.3 10.4 1.4 1 0 0 1 1 1 0 IncA protein Takusan PF04822.8 CBZ30718.1 - 0.015 15.0 2.3 0.043 13.5 1.6 1.8 1 0 0 1 1 1 0 Takusan DivIVA PF05103.8 CBZ30718.1 - 0.024 14.6 3.3 0.024 14.6 2.3 2.7 2 1 1 3 3 3 0 DivIVA protein FlaC_arch PF05377.6 CBZ30718.1 - 0.051 13.4 0.8 0.13 12.2 0.2 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Macoilin PF09726.4 CBZ30718.1 - 0.33 9.1 13.8 0.45 8.7 9.6 1.1 1 0 0 1 1 1 0 Transmembrane protein RTC PF01137.16 CBZ30719.1 - 6.9e-52 175.5 0.1 7.8e-52 175.3 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CBZ30719.1 - 6.6e-25 87.1 0.1 1e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pro_isomerase PF00160.16 CBZ30720.1 - 2.5e-13 50.5 0.0 4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 CBZ30721.1 - 1.7e-55 187.9 0.0 2e-55 187.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30721.1 - 3.5e-18 65.6 0.0 6.1e-18 64.8 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ30721.1 - 4.1e-06 26.7 0.0 0.0004 20.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CBZ30721.1 - 0.019 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like UCH PF00443.24 CBZ30722.1 - 5.4e-53 179.8 0.3 9.5e-53 179.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ30722.1 - 3.2e-25 89.1 0.0 7.1e-25 88.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 CBZ30722.1 - 9.9e-13 47.8 0.1 8.2e-11 41.6 0.0 2.8 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 CBZ30722.1 - 6.1e-10 38.8 0.4 1.9e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal Robl_LC7 PF03259.12 CBZ30723.1 - 3.1e-20 71.5 0.0 3.8e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain Epimerase_2 PF02350.14 CBZ30723.1 - 0.0065 15.2 0.0 0.01 14.6 0.0 1.3 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase DUF3800 PF12686.2 CBZ30723.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) Proteasom_Rpn13 PF04683.8 CBZ30725.1 - 1e-17 63.9 0.1 1.6e-17 63.3 0.1 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF972 PF06156.8 CBZ30726.1 - 0.015 15.5 2.5 0.015 15.5 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) XLF PF09302.6 CBZ30726.1 - 0.11 12.2 0.4 0.11 12.2 0.3 1.5 2 0 0 2 2 2 0 XLF (XRCC4-like factor) Pox_MCEL PF03291.11 CBZ30726.1 - 0.14 11.0 0.7 0.18 10.6 0.5 1.3 1 1 0 1 1 1 0 mRNA capping enzyme DUF1367 PF07105.6 CBZ30726.1 - 0.17 11.2 2.3 3.9 6.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1367) APG6 PF04111.7 CBZ30726.1 - 0.21 10.5 7.4 0.27 10.2 5.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4618 PF15397.1 CBZ30726.1 - 0.5 9.6 9.2 0.97 8.7 6.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DivIC PF04977.10 CBZ30726.1 - 3 7.3 9.1 0.4 10.1 1.3 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.1 CBZ30726.1 - 5.1 7.5 10.2 0.69 10.3 1.8 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DNA_pol_E_B PF04042.11 CBZ30727.1 - 9.3e-22 77.3 0.0 1.5e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DTW PF03942.10 CBZ30728.1 - 9.7e-27 93.5 0.1 1.8e-26 92.6 0.1 1.4 1 0 0 1 1 1 1 DTW domain C1_4 PF07975.7 CBZ30728.1 - 0.046 13.7 0.3 0.092 12.7 0.2 1.4 1 0 0 1 1 1 0 TFIIH C1-like domain zf-RING_3 PF14369.1 CBZ30728.1 - 0.3 11.1 4.8 1.8 8.6 0.3 2.5 1 1 1 2 2 2 0 zinc-finger GAS PF13851.1 CBZ30729.1 - 2.3e-62 209.8 26.4 2.3e-62 209.8 18.3 3.2 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding DUF2365 PF10157.4 CBZ30729.1 - 0.017 14.9 4.6 0.21 11.4 0.1 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2365) DUF948 PF06103.6 CBZ30729.1 - 0.96 9.3 20.6 0.3 10.9 1.0 5.7 1 1 5 6 6 6 0 Bacterial protein of unknown function (DUF948) DinB_2 PF12867.2 CBZ30729.1 - 5.6 7.3 9.9 1.6 9.0 2.0 3.2 3 1 0 3 3 3 0 DinB superfamily Ebp2 PF05890.7 CBZ30730.1 - 2.9e-57 194.0 14.2 4.8e-57 193.3 9.8 1.3 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 GvpL_GvpF PF06386.6 CBZ30730.1 - 0.95 8.9 11.6 0.049 13.2 2.5 2.2 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF EIIBC-GUT_N PF03612.9 CBZ30730.1 - 7.4 6.1 6.0 1.3 8.6 0.4 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus BTV_NS2 PF04514.7 CBZ30730.1 - 9.7 4.9 20.7 2.7 6.7 2.3 2.2 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Lysine_decarbox PF03641.9 CBZ30731.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Possible lysine decarboxylase Baculo_IE-1 PF05290.6 CBZ30732.1 - 0.03 14.0 0.3 0.035 13.8 0.2 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Caveolin PF01146.12 CBZ30732.1 - 2 7.9 4.8 3.2 7.3 3.3 1.2 1 0 0 1 1 1 0 Caveolin EMP24_GP25L PF01105.19 CBZ30733.1 - 2.9e-40 137.9 0.2 3.7e-40 137.5 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MogR_DNAbind PF12181.3 CBZ30733.1 - 0.059 13.1 0.6 0.087 12.6 0.4 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Pkinase PF00069.20 CBZ30734.1 - 9.5e-54 182.2 0.0 1.2e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30734.1 - 1e-21 77.1 0.0 2.1e-21 76.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CBZ30734.1 - 0.065 12.9 0.1 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family SH3BP5 PF05276.9 CBZ30735.1 - 0.0059 15.9 0.4 0.01 15.1 0.3 1.3 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) Ribosomal_L18p PF00861.17 CBZ30736.1 - 4.2e-38 130.1 0.6 4.2e-38 130.1 0.4 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CBZ30736.1 - 2.1e-23 82.6 5.9 2.1e-23 82.6 4.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Phage_Integr_2 PF13009.1 CBZ30736.1 - 0.13 11.1 0.3 0.2 10.5 0.2 1.2 1 0 0 1 1 1 0 Putative phage integrase Ribosomal_L18p PF00861.17 CBZ30737.1 - 4.2e-38 130.1 0.6 4.2e-38 130.1 0.4 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CBZ30737.1 - 2.1e-23 82.6 5.9 2.1e-23 82.6 4.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Phage_Integr_2 PF13009.1 CBZ30737.1 - 0.13 11.1 0.3 0.2 10.5 0.2 1.2 1 0 0 1 1 1 0 Putative phage integrase Ribosomal_L18p PF00861.17 CBZ30738.1 - 4.2e-38 130.1 0.6 4.2e-38 130.1 0.4 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CBZ30738.1 - 2.1e-23 82.6 5.9 2.1e-23 82.6 4.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Phage_Integr_2 PF13009.1 CBZ30738.1 - 0.13 11.1 0.3 0.2 10.5 0.2 1.2 1 0 0 1 1 1 0 Putative phage integrase Ribosomal_L15e PF00827.12 CBZ30739.1 - 1.9e-88 295.0 10.1 2.1e-88 294.8 7.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L36e PF01158.13 CBZ30740.1 - 7.5e-34 115.6 1.8 9.1e-34 115.3 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF1906 PF08924.6 CBZ30741.1 - 0.89 9.4 3.2 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1906) PHD PF00628.24 CBZ30742.1 - 0.0017 17.9 1.9 0.0017 17.9 1.3 2.1 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 CBZ30742.1 - 0.056 13.1 6.6 0.13 12.0 4.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 CBZ30742.1 - 0.24 11.1 9.8 0.089 12.5 3.9 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1423 PF07227.6 CBZ30742.1 - 1.6 7.3 6.4 4.4 5.8 4.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) MAD PF05557.8 CBZ30743.1 - 0.0024 16.0 4.5 0.0036 15.4 3.1 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF2205 PF10224.4 CBZ30743.1 - 0.017 14.7 1.4 0.017 14.7 1.0 2.1 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) Med3 PF11593.3 CBZ30743.1 - 0.029 13.6 0.0 0.061 12.5 0.0 1.6 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal UPF0184 PF03670.8 CBZ30743.1 - 0.17 12.0 5.0 0.06 13.5 1.2 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) NYD-SP28_assoc PF14775.1 CBZ30743.1 - 0.66 9.7 9.5 0.85 9.3 1.3 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain IncA PF04156.9 CBZ30743.1 - 0.73 9.3 10.0 1.2 8.7 6.9 1.2 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 CBZ30743.1 - 1.4 8.4 7.4 7.6 6.1 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 CBZ30743.1 - 1.6 7.6 12.2 2.8 6.8 8.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-H PF05837.7 CBZ30743.1 - 4.6 7.4 8.7 8.3 6.6 6.1 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF972 PF06156.8 CBZ30743.1 - 6.5 7.1 9.0 2.7e+02 1.9 6.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) HALZ PF02183.13 CBZ30743.1 - 6.8 6.4 11.4 1.3 8.8 1.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper ATP11 PF06644.6 CBZ30744.1 - 1.3e-23 83.8 0.9 1.6e-23 83.5 0.6 1.1 1 0 0 1 1 1 1 ATP11 protein Lysine_decarbox PF03641.9 CBZ30745.1 - 1.4e-15 57.3 0.4 4.7e-15 55.5 0.0 1.8 1 1 1 2 2 2 1 Possible lysine decarboxylase UBX PF00789.15 CBZ30746.1 - 1.9e-07 31.0 0.1 9.6e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 UBX domain Milton PF12448.3 CBZ30746.1 - 0.051 13.7 4.3 0.099 12.8 3.0 1.4 1 0 0 1 1 1 0 Kinesin associated protein Thioredoxin_7 PF13899.1 CBZ30746.1 - 0.2 11.7 0.8 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Thioredoxin-like CAF-1_p150 PF11600.3 CBZ30746.1 - 0.93 8.8 24.6 1.4 8.2 17.1 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Asp-B-Hydro_N PF05279.6 CBZ30746.1 - 1.8 8.3 15.1 2.7 7.7 10.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SAPS PF04499.10 CBZ30746.1 - 4.9 5.6 6.0 6.5 5.2 4.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Selenoprotein_S PF06936.6 CBZ30746.1 - 6.7 6.2 17.4 6.8 6.1 11.4 1.5 1 1 0 1 1 1 0 Selenoprotein S (SelS) Trypsin_2 PF13365.1 CBZ30747.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.7 1 1 0 1 1 1 0 Trypsin-like peptidase domain U3_assoc_6 PF08640.6 CBZ30748.1 - 5.1e-18 64.6 0.3 4.3e-17 61.6 0.1 2.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Ribosomal_S6e PF01092.14 CBZ30750.1 - 8.5e-39 132.0 0.2 1.6e-38 131.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e WSK PF03832.8 CBZ30750.1 - 0.032 13.5 0.3 0.032 13.5 0.2 1.9 2 0 0 2 2 2 0 WSK motif RdRP_3 PF00998.18 CBZ30750.1 - 0.066 11.7 6.0 0.078 11.4 4.2 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase RmlD_sub_bind PF04321.12 CBZ30751.1 - 2.2e-05 23.5 0.0 0.035 12.9 0.0 2.3 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_10 PF13460.1 CBZ30751.1 - 0.00044 20.3 0.0 0.00074 19.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CBZ30751.1 - 0.0026 17.2 0.0 0.0086 15.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CBZ30751.1 - 0.037 13.2 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family EF-hand_6 PF13405.1 CBZ30752.1 - 1.2e-08 34.0 0.1 0.16 11.9 0.1 3.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 CBZ30752.1 - 5.1e-07 29.7 0.0 0.11 12.6 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CBZ30752.1 - 5.4e-07 28.4 0.0 0.21 10.9 0.0 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 CBZ30752.1 - 0.0073 15.8 0.2 2.2 7.9 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 CBZ30752.1 - 0.084 12.2 0.0 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 EF hand Ank_2 PF12796.2 CBZ30753.1 - 8.7e-72 237.5 27.9 8.8e-11 42.0 0.2 14.2 8 4 9 18 18 18 13 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ30753.1 - 5.1e-42 139.6 61.2 5.3e-05 22.8 0.2 20.8 21 0 0 21 21 21 13 Ankyrin repeat Ank_4 PF13637.1 CBZ30753.1 - 2.4e-37 126.6 30.5 6.3e-06 26.5 0.1 15.3 15 3 4 19 19 19 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 CBZ30753.1 - 9.5e-35 117.8 56.5 7.7e-07 29.1 0.2 19.6 16 6 5 21 21 21 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ30753.1 - 1e-32 108.8 43.5 0.0066 16.5 0.1 20.8 23 0 0 23 23 23 10 Ankyrin repeat Filamin PF00630.14 CBZ30753.1 - 0.012 16.1 0.0 0.087 13.3 0.0 2.3 2 0 0 2 2 2 0 Filamin/ABP280 repeat DUF2454 PF10521.4 CBZ30753.1 - 0.43 9.5 0.0 1.7 7.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) Ribosomal_L32e PF01655.13 CBZ30754.1 - 1.5e-40 137.6 0.6 1.8e-40 137.4 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 SH3_9 PF14604.1 CBZ30755.1 - 3.8e-33 112.8 0.5 2.8e-13 49.2 0.0 4.6 5 0 0 5 5 5 3 Variant SH3 domain SH3_1 PF00018.23 CBZ30755.1 - 2.2e-30 103.7 0.2 4.6e-12 45.1 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 CBZ30755.1 - 2.1e-24 84.7 0.3 6.4e-12 44.7 0.1 3.8 4 0 0 4 4 4 3 Variant SH3 domain DUF4205 PF13898.1 CBZ30756.1 - 3.5e-24 85.1 0.0 6.8e-24 84.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4205) E1-E2_ATPase PF00122.15 CBZ30758.1 - 1.6e-61 207.3 1.1 3.4e-61 206.2 0.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CBZ30758.1 - 5.1e-29 101.0 2.3 5.1e-29 101.0 1.6 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CBZ30758.1 - 3.2e-25 89.8 0.0 1.4e-24 87.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CBZ30758.1 - 3.4e-15 55.7 0.0 1e-14 54.2 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CBZ30758.1 - 8.6e-10 39.0 0.0 6.3e-09 36.2 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CBZ30758.1 - 1.7e-09 36.9 0.0 3.9e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CBZ30758.1 - 1.7e-05 24.5 2.1 3.5e-05 23.5 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Kinesin PF00225.18 CBZ30759.1 - 5.4e-73 245.6 0.0 1.2e-42 145.8 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Synaptobrevin PF00957.16 CBZ30762.1 - 5.7e-14 51.4 0.1 9.9e-14 50.7 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 CBZ30762.1 - 5.5e-10 38.6 0.0 8.7e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF1510 PF07423.6 CBZ30763.1 - 0.78 9.0 8.7 1.1 8.5 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 CBZ30763.1 - 0.83 7.4 16.1 1.1 7.1 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family Usp PF00582.21 CBZ30763.1 - 4 7.6 6.6 9.5 6.4 1.4 2.2 2 0 0 2 2 2 0 Universal stress protein family Daxx PF03344.10 CBZ30763.1 - 4.4 5.6 16.0 6.9 5.0 11.1 1.2 1 0 0 1 1 1 0 Daxx Family TFIID-31kDa PF02291.10 CBZ30764.1 - 0.051 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Lipase_3 PF01764.20 CBZ30765.1 - 3.5e-05 23.4 0.0 0.00014 21.5 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 CBZ30765.1 - 0.00023 20.8 0.0 0.00048 19.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 CBZ30765.1 - 0.043 14.0 0.1 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Thioesterase domain adh_short PF00106.20 CBZ30766.1 - 9.4e-11 41.8 0.1 2.7e-10 40.4 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase HTH_8 PF02954.14 CBZ30766.1 - 0.019 14.4 0.0 0.097 12.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family A_deaminase PF00962.17 CBZ30767.1 - 1.4e-55 188.5 0.0 1.7e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase adh_short PF00106.20 CBZ30768.1 - 2.7e-12 46.9 1.7 3.4e-11 43.3 1.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CBZ30768.1 - 9.7e-05 22.0 1.4 0.00023 20.8 0.7 1.8 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.13 CBZ30768.1 - 0.0071 16.0 0.2 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 CBZ30768.1 - 0.015 14.5 0.1 0.059 12.6 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family THF_DHG_CYH_C PF02882.14 CBZ30768.1 - 0.019 14.0 0.0 0.041 12.9 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.1 CBZ30768.1 - 0.025 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CBZ30768.1 - 0.054 13.5 0.2 0.13 12.2 0.2 1.6 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 CBZ30768.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ribosomal_L11_N PF03946.9 CBZ30770.1 - 7.6e-15 54.1 0.2 1.3e-14 53.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CBZ30770.1 - 2.4e-11 43.6 0.5 4.5e-11 42.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain RRM_1 PF00076.17 CBZ30771.1 - 4.9e-36 122.1 0.0 4.6e-17 61.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ30771.1 - 2.3e-29 101.1 0.1 3.9e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ30771.1 - 2.4e-10 40.0 0.0 4.5e-05 23.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CBZ30771.1 - 0.0002 21.0 0.4 1.4 8.7 0.0 3.5 3 1 0 3 3 3 2 Limkain b1 KMP11 PF03037.11 CBZ30772.1 - 2.7e-55 184.9 17.8 3e-55 184.8 12.3 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.13 CBZ30772.1 - 0.0064 16.0 4.8 0.027 14.0 3.3 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.6 CBZ30772.1 - 0.066 12.0 2.4 0.071 11.9 1.7 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain AAA_32 PF13654.1 CBZ30772.1 - 0.073 11.7 5.7 0.074 11.7 4.0 1.0 1 0 0 1 1 1 0 AAA domain Brr6_like_C_C PF10104.4 CBZ30772.1 - 0.079 12.4 1.0 0.087 12.3 0.7 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Herpes_BLRF2 PF05812.7 CBZ30772.1 - 0.083 12.7 1.7 0.11 12.3 1.2 1.3 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein FdsD PF11390.3 CBZ30772.1 - 0.097 12.7 1.9 0.25 11.4 1.3 1.9 1 1 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD FCH PF00611.18 CBZ30772.1 - 0.13 12.4 5.0 1.4 9.1 3.4 2.0 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain T5orf172 PF10544.4 CBZ30772.1 - 0.15 12.4 2.2 0.17 12.2 1.5 1.2 1 0 0 1 1 1 0 T5orf172 domain DUF4404 PF14357.1 CBZ30772.1 - 0.15 12.4 3.8 1.2 9.6 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) ARL2_Bind_BART PF11527.3 CBZ30772.1 - 0.18 11.6 10.0 0.24 11.2 6.7 1.4 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART NYD-SP28 PF14772.1 CBZ30772.1 - 0.18 11.8 8.8 1.6 8.8 0.3 2.5 2 1 0 2 2 2 0 Sperm tail Metal_resist PF13801.1 CBZ30772.1 - 0.23 11.4 2.4 0.62 10.0 0.1 2.0 1 1 1 2 2 2 0 Heavy-metal resistance HrcA PF01628.16 CBZ30772.1 - 0.28 10.7 1.2 0.32 10.5 0.9 1.0 1 0 0 1 1 1 0 HrcA protein C terminal domain INCENP_N PF12178.3 CBZ30772.1 - 0.3 10.6 2.2 9.9 5.8 0.1 2.5 2 1 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal Vps54 PF07928.7 CBZ30772.1 - 0.65 10.1 4.1 0.82 9.7 1.4 1.8 2 0 0 2 2 2 0 Vps54-like protein DUF2884 PF11101.3 CBZ30772.1 - 0.79 9.0 9.1 2.1 7.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF3994 PF13159.1 CBZ30772.1 - 1.1 9.5 4.5 0.52 10.5 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) DUF3417 PF11897.3 CBZ30772.1 - 1.3 9.0 5.0 8.8 6.3 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) DUF148 PF02520.12 CBZ30772.1 - 1.8 8.3 8.2 17 5.2 3.7 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 TipAS PF07739.8 CBZ30772.1 - 2 8.7 10.8 1.4 9.2 2.4 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain YtxH PF12732.2 CBZ30772.1 - 2.1 8.7 5.0 9.4 6.6 3.5 1.9 1 1 0 1 1 1 0 YtxH-like protein Pox_polyA_pol_N PF12630.2 CBZ30772.1 - 2.6 8.1 4.9 4 7.5 3.3 1.5 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Mitofilin PF09731.4 CBZ30772.1 - 2.9 6.4 10.4 3.7 6.0 7.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein PWWP PF00855.12 CBZ30772.1 - 5.1 7.3 6.8 8 6.7 4.7 1.4 1 1 0 1 1 1 0 PWWP domain YlqD PF11068.3 CBZ30772.1 - 5.6 7.0 8.3 15 5.6 5.8 1.6 1 1 0 1 1 1 0 YlqD protein FadA PF09403.5 CBZ30772.1 - 7.3 6.6 10.8 17 5.4 7.5 1.6 1 1 0 1 1 1 0 Adhesion protein FadA KMP11 PF03037.11 CBZ30773.1 - 3.9e-56 187.6 17.4 4.3e-56 187.4 12.0 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.13 CBZ30773.1 - 0.015 14.7 5.1 0.075 12.5 3.5 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.6 CBZ30773.1 - 0.049 12.5 2.1 0.051 12.4 1.5 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain FdsD PF11390.3 CBZ30773.1 - 0.086 12.9 1.4 0.19 11.8 1.0 1.7 1 1 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Herpes_BLRF2 PF05812.7 CBZ30773.1 - 0.095 12.5 2.9 0.11 12.2 2.0 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Metal_resist PF13801.1 CBZ30773.1 - 0.12 12.4 2.8 0.64 10.0 0.2 2.0 1 1 1 2 2 2 0 Heavy-metal resistance Brr6_like_C_C PF10104.4 CBZ30773.1 - 0.13 11.7 0.6 0.15 11.6 0.4 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain FCH PF00611.18 CBZ30773.1 - 0.21 11.8 4.7 0.17 12.1 0.6 2.0 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF3584 PF12128.3 CBZ30773.1 - 0.23 8.7 6.8 0.26 8.5 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) INCENP_N PF12178.3 CBZ30773.1 - 0.3 10.6 2.2 9.9 5.8 0.1 2.5 2 1 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal NYD-SP28 PF14772.1 CBZ30773.1 - 0.31 11.1 8.5 1.6 8.8 0.3 2.3 2 1 0 2 2 2 0 Sperm tail GrpE PF01025.14 CBZ30773.1 - 0.31 10.5 5.5 0.36 10.3 3.8 1.2 1 0 0 1 1 1 0 GrpE TipAS PF07739.8 CBZ30773.1 - 0.34 11.2 8.8 0.63 10.3 1.9 2.1 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF1798 PF08807.5 CBZ30773.1 - 0.67 9.6 6.7 0.3 10.8 2.4 1.8 2 0 0 2 2 2 0 Bacterial domain of unknown function (DUF1798) DIOX_N PF14226.1 CBZ30773.1 - 0.89 10.0 5.8 1 9.9 4.1 1.1 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal ARL2_Bind_BART PF11527.3 CBZ30773.1 - 0.96 9.2 8.8 1.7 8.4 6.0 1.4 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART Vps54 PF07928.7 CBZ30773.1 - 1.1 9.4 3.8 1.4 9.0 1.2 1.8 2 0 0 2 2 2 0 Vps54-like protein DUF2884 PF11101.3 CBZ30773.1 - 1.4 8.2 8.4 2.1 7.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) Mitofilin PF09731.4 CBZ30773.1 - 1.7 7.2 10.2 2.2 6.8 7.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein YtxH PF12732.2 CBZ30773.1 - 2.5 8.5 5.1 11 6.4 3.5 1.9 1 1 0 1 1 1 0 YtxH-like protein Rho_Binding PF08912.6 CBZ30773.1 - 4.2 7.7 10.9 0.99 9.7 2.2 2.2 1 1 1 2 2 2 0 Rho Binding Phage_Gp23 PF10669.4 CBZ30773.1 - 5.7 7.0 7.8 1.2 9.2 2.7 1.7 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) PWWP PF00855.12 CBZ30773.1 - 6.1 7.1 7.0 10 6.3 4.9 1.4 1 1 0 1 1 1 0 PWWP domain FadA PF09403.5 CBZ30773.1 - 7.9 6.5 10.7 18 5.3 7.5 1.6 1 1 0 1 1 1 0 Adhesion protein FadA KMP11 PF03037.11 CBZ30774.1 - 3e-57 191.1 16.9 3.3e-57 191.0 11.7 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.13 CBZ30774.1 - 0.0052 16.3 4.2 0.025 14.0 3.0 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.6 CBZ30774.1 - 0.04 12.8 1.8 0.041 12.7 1.2 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain AAA_32 PF13654.1 CBZ30774.1 - 0.052 12.1 5.1 0.053 12.1 3.6 1.0 1 0 0 1 1 1 0 AAA domain Brr6_like_C_C PF10104.4 CBZ30774.1 - 0.065 12.7 0.6 0.072 12.5 0.4 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain FdsD PF11390.3 CBZ30774.1 - 0.087 12.9 1.6 0.21 11.6 1.1 1.8 1 1 0 1 1 1 0 NADH-dependant formate dehydrogenase delta subunit FdsD Psb28 PF03912.9 CBZ30774.1 - 0.094 12.6 1.2 0.12 12.3 0.7 1.3 1 1 0 1 1 1 0 Psb28 protein Herpes_BLRF2 PF05812.7 CBZ30774.1 - 0.094 12.5 1.7 0.12 12.1 1.2 1.3 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein DUF3584 PF12128.3 CBZ30774.1 - 0.1 9.8 6.3 0.12 9.6 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NYD-SP28 PF14772.1 CBZ30774.1 - 0.14 12.2 8.0 1.6 8.8 0.3 2.5 2 1 0 2 2 2 0 Sperm tail FCH PF00611.18 CBZ30774.1 - 0.17 12.0 4.5 0.18 12.0 1.0 1.9 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain ARL2_Bind_BART PF11527.3 CBZ30774.1 - 0.19 11.5 9.0 0.32 10.8 6.1 1.4 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART GrpE PF01025.14 CBZ30774.1 - 0.19 11.2 5.4 0.23 11.0 3.7 1.2 1 0 0 1 1 1 0 GrpE T5orf172 PF10544.4 CBZ30774.1 - 0.22 11.9 2.5 0.26 11.7 1.7 1.2 1 0 0 1 1 1 0 T5orf172 domain Metal_resist PF13801.1 CBZ30774.1 - 0.25 11.3 2.5 0.76 9.7 0.1 2.0 1 1 1 2 2 2 0 Heavy-metal resistance DUF4404 PF14357.1 CBZ30774.1 - 0.27 11.6 4.7 1.4 9.3 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) INCENP_N PF12178.3 CBZ30774.1 - 0.31 10.6 2.2 9.9 5.8 0.1 2.5 2 1 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal Vps54 PF07928.7 CBZ30774.1 - 0.66 10.1 4.1 0.82 9.7 1.4 1.8 2 0 0 2 2 2 0 Vps54-like protein DUF2884 PF11101.3 CBZ30774.1 - 0.7 9.2 8.6 2.1 7.6 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF3417 PF11897.3 CBZ30774.1 - 1.1 9.2 5.1 8.6 6.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) YtxH PF12732.2 CBZ30774.1 - 1.3 9.4 4.2 5.6 7.4 2.9 1.9 1 1 0 1 1 1 0 YtxH-like protein Rho_Binding PF08912.6 CBZ30774.1 - 2.2 8.6 10.2 0.46 10.8 1.9 2.2 1 1 1 2 2 2 0 Rho Binding Mitofilin PF09731.4 CBZ30774.1 - 2.7 6.5 9.7 3.6 6.1 6.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TipAS PF07739.8 CBZ30774.1 - 2.7 8.3 10.5 1.9 8.8 2.2 2.0 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain PWWP PF00855.12 CBZ30774.1 - 4.5 7.5 6.6 7 6.9 4.6 1.4 1 1 0 1 1 1 0 PWWP domain YlqD PF11068.3 CBZ30774.1 - 6.1 6.8 7.4 16 5.5 5.1 1.6 1 1 0 1 1 1 0 YlqD protein Vma12 PF11712.3 CBZ30774.1 - 9.4 5.9 9.2 2.8 7.6 2.4 2.1 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ATG_C PF09333.6 CBZ30777.1 - 0.026 14.6 0.1 0.54 10.4 0.1 2.7 1 1 0 1 1 1 0 ATG C terminal domain ATP-grasp_4 PF13535.1 CBZ30778.1 - 9e-24 84.2 0.0 6.8e-23 81.3 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CBZ30778.1 - 4e-08 32.3 0.0 0.00052 18.8 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 CBZ30778.1 - 0.023 14.5 0.0 0.09 12.6 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.12 CBZ30778.1 - 0.035 13.4 0.0 4.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 CBZ30778.1 - 0.1 12.1 0.0 0.71 9.4 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Helicase_C PF00271.26 CBZ30779.1 - 1.7e-07 31.0 0.0 4.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CBZ30779.1 - 4.1e-05 23.1 0.0 0.00012 21.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CBZ30779.1 - 0.078 13.1 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 CBZ30784.1 - 8.3e-42 143.1 0.0 2.2e-24 85.9 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30784.1 - 2.6e-26 92.2 0.0 1.3e-22 80.1 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CBZ30784.1 - 2.8e-06 26.5 0.0 0.0042 16.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.6 CBZ30784.1 - 0.1 11.3 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HEAT_EZ PF13513.1 CBZ30785.1 - 4.7e-07 30.1 5.9 0.029 14.8 0.0 6.3 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.17 CBZ30785.1 - 5.3e-05 22.9 5.1 8.7 6.7 0.0 7.2 6 0 0 6 6 6 1 HEAT repeat 2Fe-2S_thioredx PF01257.14 CBZ30785.1 - 0.0063 16.1 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin IBN_N PF03810.14 CBZ30785.1 - 0.01 15.7 2.2 0.061 13.2 0.7 2.7 2 0 0 2 2 2 0 Importin-beta N-terminal domain HEAT_2 PF13646.1 CBZ30785.1 - 0.026 14.7 0.2 1.5 9.1 0.0 3.7 2 1 1 3 3 3 0 HEAT repeats Ipi1_N PF12333.3 CBZ30785.1 - 0.071 13.0 0.6 29 4.7 0.0 3.8 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 CBZ30785.1 - 0.098 10.9 0.0 0.23 9.7 0.0 1.6 1 0 0 1 1 1 0 Adaptin N terminal region CAF1 PF04857.15 CBZ30786.1 - 5.1e-25 88.2 0.0 1.2e-16 60.8 0.0 2.2 2 0 0 2 2 2 2 CAF1 family ribonuclease PUF PF00806.14 CBZ30786.1 - 0.12 11.8 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Peptidase_M24 PF00557.19 CBZ30787.1 - 1.3e-49 168.5 0.3 2e-49 167.9 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CBZ30787.1 - 4.3e-27 94.1 0.0 7.2e-27 93.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF1764 PF08576.5 CBZ30788.1 - 1.5e-16 60.9 2.2 2.4e-15 57.1 0.1 2.5 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) Herpes_US12 PF05363.7 CBZ30788.1 - 0.26 11.8 1.7 1.6 9.2 0.1 2.3 2 0 0 2 2 2 0 Herpesvirus US12 family SET PF00856.23 CBZ30789.1 - 5.8e-07 29.9 0.0 4.7e-05 23.7 0.0 2.8 1 1 0 1 1 1 1 SET domain Spt4 PF06093.8 CBZ30791.1 - 1e-09 38.1 0.1 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger WD40 PF00400.27 CBZ30792.1 - 4.5e-07 29.5 0.7 0.0054 16.5 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.1 CBZ30792.1 - 0.00014 21.4 0.4 0.00014 21.4 0.3 2.5 3 0 0 3 3 3 1 PQQ-like domain Hira PF07569.6 CBZ30792.1 - 0.0055 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 TUP1-like enhancer of split LRR_6 PF13516.1 CBZ30792.1 - 0.086 12.9 0.2 3.9 7.8 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich repeat UCH PF00443.24 CBZ30793.1 - 2.9e-40 138.0 0.0 1.4e-39 135.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CBZ30793.1 - 6e-09 35.7 0.0 7.2e-06 25.6 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Vps5 PF09325.5 CBZ30794.1 - 1.9e-18 66.6 4.3 2.6e-18 66.1 3.0 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CBZ30794.1 - 5.5e-16 58.3 0.0 1.3e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 CBZ30794.1 - 0.0067 15.7 1.0 0.035 13.3 0.7 1.9 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DUF4164 PF13747.1 CBZ30794.1 - 0.23 11.6 3.9 0.87 9.7 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) FAA_hydrolase PF01557.13 CBZ30796.1 - 5e-40 137.2 0.1 3.7e-39 134.4 0.1 1.9 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3490 PF11995.3 CBZ30796.1 - 0.00053 19.5 0.0 0.0019 17.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3490) HECT PF00632.20 CBZ30797.1 - 2.6e-87 292.9 0.0 5.6e-87 291.8 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WWE PF02825.15 CBZ30797.1 - 0.014 14.8 0.7 0.031 13.6 0.5 1.6 1 0 0 1 1 1 0 WWE domain DUF3492 PF11997.3 CBZ30798.1 - 0.047 13.2 3.2 0.072 12.6 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3492) Nop53 PF07767.6 CBZ30799.1 - 1e-10 41.1 20.7 6.6e-10 38.5 14.4 2.0 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.7 CBZ30799.1 - 0.021 13.2 18.8 0.029 12.7 13.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MAT1 PF06391.8 CBZ30799.1 - 7.8 6.0 12.8 0.26 10.8 3.2 2.2 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 LMBR1 PF04791.11 CBZ30800.1 - 1.2 7.6 2.8 1.9 6.9 1.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GAS PF13851.1 CBZ30800.1 - 1.4 8.0 19.3 1.4 8.0 8.1 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EcKinase PF02958.15 CBZ30800.1 - 1.8 7.6 6.4 3.6 6.6 4.4 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase V_ATPase_I PF01496.14 CBZ30800.1 - 3.7 5.2 7.6 5.4 4.7 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2229 PF09989.4 CBZ30800.1 - 3.8 6.9 3.6 9.1 5.6 2.5 1.7 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Yos1 PF08571.5 CBZ30802.1 - 1.7e-29 101.7 0.1 2.4e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 Yos1-like zf-RING_2 PF13639.1 CBZ30803.1 - 2.1e-14 53.0 15.7 5.3e-07 29.3 0.4 3.7 4 0 0 4 4 4 2 Ring finger domain zf-RING_5 PF14634.1 CBZ30803.1 - 4.2e-08 32.7 17.5 8.1e-05 22.2 0.1 4.3 4 1 0 4 4 4 2 zinc-RING finger domain zf-rbx1 PF12678.2 CBZ30803.1 - 1.1e-06 28.5 6.6 0.041 13.9 0.1 4.0 3 1 0 3 3 3 2 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CBZ30803.1 - 2.3e-05 24.3 16.4 0.0023 17.9 0.5 4.0 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ30803.1 - 2.6e-05 23.7 15.9 0.0013 18.3 0.4 3.9 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) IQ PF00612.22 CBZ30803.1 - 4.4e-05 22.7 2.2 0.00025 20.4 1.6 2.4 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-C3HC4 PF00097.20 CBZ30803.1 - 0.015 14.9 17.1 0.32 10.6 0.9 4.7 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 CBZ30806.1 - 1.3e-25 88.8 0.1 1.3e-14 53.5 0.0 3.6 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ30806.1 - 7.7e-24 83.4 0.2 3.6e-11 42.8 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 CBZ30807.1 - 2.8e-33 115.2 0.0 4.7e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CBZ30807.1 - 2.2e-16 60.1 0.5 7e-12 45.5 0.0 3.1 3 0 0 3 3 3 2 Flavodoxin FAD_binding_6 PF00970.19 CBZ30807.1 - 2.8e-05 24.1 0.0 8.2e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CBZ30807.1 - 0.00073 20.0 0.0 0.029 14.9 0.0 2.5 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain Cortex-I_coil PF09304.5 CBZ30808.1 - 0.0094 15.9 1.7 0.017 15.1 1.2 1.3 1 0 0 1 1 1 1 Cortexillin I, coiled coil IncA PF04156.9 CBZ30808.1 - 0.066 12.8 2.3 0.1 12.1 1.6 1.2 1 0 0 1 1 1 0 IncA protein CcoS PF03597.10 CBZ30809.1 - 0.03 13.7 0.3 0.053 12.9 0.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Hexokinase_2 PF03727.11 CBZ30809.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Hexokinase zf-DHHC PF01529.15 CBZ30810.1 - 1.6e-27 95.9 4.8 1.6e-27 95.9 3.4 1.6 1 1 1 2 2 2 1 DHHC palmitoyltransferase PTP_N PF12453.3 CBZ30810.1 - 0.043 13.4 3.4 0.1 12.2 2.3 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Transgly_assoc PF04226.8 CBZ30810.1 - 0.49 10.5 8.4 0.52 10.4 0.4 2.6 2 0 0 2 2 2 0 Transglycosylase associated protein DUF4491 PF14898.1 CBZ30810.1 - 0.56 10.3 6.6 1.5 8.9 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) DUF4149 PF13664.1 CBZ30810.1 - 2.2 8.4 9.5 1.1 9.3 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) NIF PF03031.13 CBZ30812.1 - 3.6e-27 94.9 0.1 5.7e-27 94.3 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CBZ30812.1 - 0.0049 17.1 0.4 0.0069 16.6 0.3 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase zf-HC5HC2H PF13771.1 CBZ30813.1 - 2.3e-07 30.8 6.6 2.3e-07 30.8 4.6 2.2 2 1 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CBZ30813.1 - 0.00013 21.9 9.1 0.00013 21.9 6.3 2.4 2 1 0 2 2 2 1 PHD-zinc-finger like domain TruD PF01142.13 CBZ30814.1 - 6.9e-06 24.9 0.0 0.077 11.6 0.0 2.2 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Ank PF00023.25 CBZ30817.1 - 2.7e-28 96.3 3.3 6.8e-13 47.7 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 CBZ30817.1 - 1.5e-26 92.2 2.6 1.4e-11 44.6 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 CBZ30817.1 - 4e-26 91.1 1.6 1.3e-16 60.6 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CBZ30817.1 - 7e-26 89.6 7.2 3e-11 43.1 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CBZ30817.1 - 1.3e-22 77.6 0.4 1.7e-08 33.9 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat HSBP1 PF06825.7 CBZ30818.1 - 1.4e-24 85.3 4.7 1.6e-24 85.2 3.2 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF2884 PF11101.3 CBZ30818.1 - 0.0035 16.7 3.0 0.0038 16.6 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2884) SF-assemblin PF06705.6 CBZ30818.1 - 0.0038 16.4 0.1 0.0044 16.2 0.1 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin BLOC1_2 PF10046.4 CBZ30818.1 - 0.0038 17.3 0.4 0.0048 16.9 0.3 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 HR1 PF02185.11 CBZ30818.1 - 0.0056 16.3 0.9 0.028 14.1 0.2 1.9 1 1 0 2 2 2 1 Hr1 repeat FtsK_SpoIIIE PF01580.13 CBZ30818.1 - 0.0069 15.8 0.1 0.0073 15.8 0.0 1.0 1 0 0 1 1 1 1 FtsK/SpoIIIE family UPF0184 PF03670.8 CBZ30818.1 - 0.0077 16.3 0.1 0.0097 16.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0184) Phage_GPO PF05929.6 CBZ30818.1 - 0.008 15.4 0.3 0.008 15.4 0.2 1.0 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase DUF241 PF03087.9 CBZ30818.1 - 0.0086 15.5 0.5 0.0088 15.5 0.3 1.0 1 0 0 1 1 1 1 Arabidopsis protein of unknown function YvrJ PF12841.2 CBZ30818.1 - 0.011 15.0 0.5 0.16 11.2 0.2 2.2 2 0 0 2 2 2 0 YvrJ protein family Syntaxin PF00804.20 CBZ30818.1 - 0.013 15.6 0.5 0.013 15.6 0.3 1.1 1 0 0 1 1 1 0 Syntaxin Baculo_PEP_C PF04513.7 CBZ30818.1 - 0.015 15.1 0.0 0.017 14.9 0.0 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SseC PF04888.7 CBZ30818.1 - 0.017 14.4 0.4 0.019 14.3 0.3 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Apolipoprotein PF01442.13 CBZ30818.1 - 0.017 14.6 0.1 0.022 14.2 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2365 PF10157.4 CBZ30818.1 - 0.023 14.5 0.1 0.029 14.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) DUF4618 PF15397.1 CBZ30818.1 - 0.027 13.8 0.2 0.031 13.6 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Not3 PF04065.10 CBZ30818.1 - 0.046 12.9 0.4 0.048 12.9 0.3 1.0 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Transposase_22 PF02994.9 CBZ30818.1 - 0.051 12.0 0.2 0.051 12.0 0.1 1.1 1 0 0 1 1 1 0 L1 transposable element Tmemb_cc2 PF10267.4 CBZ30818.1 - 0.051 12.1 0.2 0.056 12.0 0.1 1.0 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2130 PF09903.4 CBZ30818.1 - 0.057 12.1 0.2 0.063 12.0 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) Fzo_mitofusin PF04799.8 CBZ30818.1 - 0.058 12.7 0.2 0.059 12.7 0.2 1.0 1 0 0 1 1 1 0 fzo-like conserved region MtrB PF05440.7 CBZ30818.1 - 0.068 13.2 0.3 0.091 12.8 0.2 1.3 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B TPR_MLP1_2 PF07926.7 CBZ30818.1 - 0.069 12.8 0.2 0.089 12.5 0.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HLH PF00010.21 CBZ30818.1 - 0.071 12.8 0.1 0.51 10.0 0.0 1.9 1 1 1 2 2 2 0 Helix-loop-helix DNA-binding domain HalX PF08663.5 CBZ30818.1 - 0.075 13.0 0.4 0.5 10.3 0.3 2.0 1 1 0 1 1 1 0 HalX domain FliD_C PF07195.7 CBZ30818.1 - 0.087 12.0 0.1 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF4113 PF13438.1 CBZ30818.1 - 0.11 12.1 0.1 0.92 9.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) ATC_hydrolase PF14196.1 CBZ30818.1 - 0.11 12.8 0.1 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Matrilin_ccoil PF10393.4 CBZ30818.1 - 0.11 11.8 0.1 5.2 6.5 0.0 2.2 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF4525 PF15027.1 CBZ30818.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) Osmo_CC PF08946.5 CBZ30818.1 - 0.12 12.3 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil Phasin PF05597.6 CBZ30818.1 - 0.13 12.0 0.3 0.29 10.8 0.2 1.5 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FlxA PF14282.1 CBZ30818.1 - 0.15 12.0 2.3 0.46 10.4 0.9 1.8 1 1 1 2 2 2 0 FlxA-like protein DUF948 PF06103.6 CBZ30818.1 - 0.15 11.8 0.7 5.9 6.8 0.1 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HSCB_C PF07743.8 CBZ30818.1 - 0.22 12.0 4.1 0.42 11.0 2.8 1.5 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain SlyX PF04102.7 CBZ30818.1 - 2 8.8 4.2 5.5 7.4 0.5 2.1 1 1 1 2 2 2 0 SlyX BTB_2 PF02214.17 CBZ30819.1 - 3.4e-11 43.1 0.1 9.3e-11 41.8 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain DUF3181 PF11378.3 CBZ30819.1 - 0.047 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) Tropomyosin PF00261.15 CBZ30819.1 - 0.16 11.0 3.0 0.25 10.4 2.1 1.2 1 0 0 1 1 1 0 Tropomyosin TRAPPC9-Trs120 PF08626.6 CBZ30820.1 - 1.2e-07 29.5 0.0 5.3e-05 20.8 0.0 3.5 3 1 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SNARE PF05739.14 CBZ30822.1 - 5.1e-20 70.9 2.8 7.6e-20 70.3 0.4 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CBZ30822.1 - 0.00052 20.1 12.5 0.0013 18.8 1.4 2.6 1 1 2 3 3 3 2 Syntaxin MutS_III PF05192.13 CBZ30822.1 - 0.072 12.8 0.3 0.072 12.8 0.2 2.1 2 1 0 2 2 2 0 MutS domain III Lipoprotein_6 PF01441.14 CBZ30822.1 - 0.09 12.6 1.3 0.56 10.0 0.1 2.2 2 0 0 2 2 2 0 Lipoprotein Syntaxin-18_N PF10496.4 CBZ30822.1 - 0.12 12.2 1.5 1.8 8.4 0.1 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Acyl-CoA_dh_1 PF00441.19 CBZ30824.1 - 2e-41 141.5 3.1 2.9e-41 141.0 2.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 CBZ30824.1 - 8.5e-23 81.0 0.0 1.9e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 CBZ30824.1 - 1.6e-20 73.7 0.1 2.4e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 CBZ30824.1 - 3.4e-19 68.0 0.4 1.1e-18 66.5 0.4 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain GalKase_gal_bdg PF10509.4 CBZ30825.1 - 5.6e-18 63.9 0.0 1.3e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 CBZ30825.1 - 9.2e-08 32.1 0.0 2.9e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 CBZ30825.1 - 2.3e-07 30.7 0.2 5.5e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF2746 PF10874.3 CBZ30826.1 - 3 8.0 9.4 2.6 8.3 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2746) MMR_HSR1 PF01926.18 CBZ30827.1 - 0.00028 20.7 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ30827.1 - 0.0016 17.7 0.0 0.0054 16.0 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 CBZ30827.1 - 0.0072 16.4 0.0 0.18 11.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBZ30827.1 - 0.033 13.8 0.1 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 CBZ30827.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 CBZ30827.1 - 0.14 12.6 0.0 0.71 10.3 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Septin PF00735.13 CBZ30827.1 - 0.18 10.8 0.1 6.5 5.6 0.1 2.7 3 0 0 3 3 3 0 Septin IQ PF00612.22 CBZ30828.1 - 0.0025 17.3 2.4 0.0078 15.7 1.7 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif MFS_1 PF07690.11 CBZ30829.1 - 8.3e-28 97.1 39.2 8.7e-22 77.3 11.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ30829.1 - 1.9e-11 43.1 11.5 1.9e-11 43.1 8.0 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter Sec62 PF03839.11 CBZ30829.1 - 0.21 10.9 2.2 0.44 9.9 1.5 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4492 PF14899.1 CBZ30830.1 - 0.022 14.2 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Hum_adeno_E3A PF05393.6 CBZ30830.1 - 0.03 14.0 0.2 0.064 12.9 0.2 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein FAM163 PF15069.1 CBZ30830.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 FAM163 family GP41 PF00517.12 CBZ30830.1 - 0.16 11.5 0.4 0.23 10.9 0.3 1.2 1 0 0 1 1 1 0 Retroviral envelope protein ATP-synt_8 PF00895.15 CBZ30830.1 - 4.8 7.4 7.0 0.79 9.9 1.9 1.9 2 0 0 2 2 2 0 ATP synthase protein 8 Abhydrolase_6 PF12697.2 CBZ30831.1 - 5.1e-06 26.5 0.2 1.2e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF818 PF05677.7 CBZ30831.1 - 8.2e-06 24.7 0.0 1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_5 PF12695.2 CBZ30831.1 - 8.9e-06 25.5 0.1 4.9e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CBZ30831.1 - 0.001 18.3 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 CBZ30831.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.7 CBZ30831.1 - 0.03 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 CBZ30831.1 - 0.039 13.5 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 CBZ30831.1 - 0.1 11.9 0.1 0.43 9.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) MFS_1 PF07690.11 CBZ30832.1 - 1.7e-25 89.5 30.8 3.2e-19 68.8 12.3 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 CBZ30832.1 - 0.043 13.6 0.0 0.043 13.6 0.0 3.4 4 0 0 4 4 4 0 MFS_1 like family MFS_1 PF07690.11 CBZ30833.1 - 5.6e-23 81.2 37.1 1.3e-18 66.8 7.3 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ30833.1 - 9.1e-06 24.5 4.4 9.1e-06 24.5 3.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Cupin_2 PF07883.6 CBZ30834.1 - 0.1 12.0 0.1 0.29 10.6 0.1 1.7 1 0 0 1 1 1 0 Cupin domain Aminotran_5 PF00266.14 CBZ30835.1 - 2e-50 171.5 0.1 4.9e-31 107.7 0.1 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 CBZ30835.1 - 0.00067 18.8 0.1 0.002 17.3 0.0 1.7 2 1 0 2 2 2 1 Beta-eliminating lyase Leo1 PF04004.8 CBZ30836.1 - 3.4e-19 69.1 0.8 1.5e-18 67.0 0.0 2.2 2 0 0 2 2 2 1 Leo1-like protein DUF4407 PF14362.1 CBZ30836.1 - 1.6 7.6 8.3 2.9 6.7 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Alb1 PF09135.6 CBZ30837.1 - 0.099 13.2 22.4 64 4.2 15.5 2.3 1 1 0 1 1 1 0 Alb1 DUF4407 PF14362.1 CBZ30837.1 - 0.33 9.8 9.6 0.42 9.5 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1053 PF06327.9 CBZ30837.1 - 0.37 11.1 3.8 0.34 11.2 1.3 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) TRAP_alpha PF03896.11 CBZ30837.1 - 1.9 7.4 4.4 2.2 7.1 0.1 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Pox_Ag35 PF03286.9 CBZ30837.1 - 3.8 6.9 13.2 0.73 9.3 3.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Caudo_TAP PF02413.12 CBZ30837.1 - 5.6 7.1 8.0 1.4 9.0 2.6 1.9 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein Pkinase PF00069.20 CBZ30838.1 - 9.6e-09 34.7 0.0 1.3e-05 24.5 0.0 3.0 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30838.1 - 1.1e-06 27.8 0.0 6.1e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sybindin PF04099.7 CBZ30839.1 - 8e-18 64.5 0.1 9.1e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family CHU_C PF13585.1 CBZ30839.1 - 0.048 13.5 0.1 0.082 12.7 0.1 1.4 1 0 0 1 1 1 0 C-terminal domain of CHU protein family Tmpp129 PF10272.4 CBZ30839.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor SpoU_methylase PF00588.14 CBZ30840.1 - 1e-08 35.1 0.1 6.3e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 SpoU rRNA Methylase family Tctex-1 PF03645.8 CBZ30842.1 - 1.2e-28 98.8 0.0 1.4e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DSPc PF00782.15 CBZ30842.1 - 0.043 13.3 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Lip_prot_lig_C PF10437.4 CBZ30842.1 - 0.13 11.9 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus M-inducer_phosp PF06617.8 CBZ30843.1 - 0.032 13.2 1.2 0.76 8.7 0.1 2.8 2 1 0 3 3 3 0 M-phase inducer phosphatase DUF1673 PF07895.6 CBZ30844.1 - 0.85 9.1 8.0 0.64 9.5 3.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Cupin_8 PF13621.1 CBZ30845.1 - 2e-44 151.9 0.1 3.3e-43 147.9 0.0 2.1 2 0 0 2 2 2 1 Cupin-like domain LCM PF04072.9 CBZ30845.1 - 9.4e-17 61.1 0.0 1.1e-08 34.9 0.0 2.8 2 1 0 2 2 2 2 Leucine carboxyl methyltransferase Kelch_5 PF13854.1 CBZ30845.1 - 1.7e-10 40.5 0.7 0.2 11.6 0.0 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 CBZ30845.1 - 6.9e-08 32.4 10.4 0.071 13.3 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_4 PF13418.1 CBZ30845.1 - 0.00018 21.2 9.2 4.7 7.0 0.0 6.2 7 0 0 7 7 7 2 Galactose oxidase, central domain Cupin_4 PF08007.7 CBZ30845.1 - 0.0014 17.9 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein E1-E2_ATPase PF00122.15 CBZ30845.1 - 0.059 12.3 0.1 0.099 11.6 0.1 1.3 1 0 0 1 1 1 0 E1-E2 ATPase PPR PF01535.15 CBZ30846.1 - 1.7e-24 84.0 20.5 0.025 14.5 0.0 11.8 12 0 0 12 12 12 6 PPR repeat PPR_2 PF13041.1 CBZ30846.1 - 5.1e-24 83.9 8.8 1.7e-06 27.8 0.0 9.4 6 4 3 9 9 9 6 PPR repeat family PPR_3 PF13812.1 CBZ30846.1 - 2.1e-17 61.8 25.0 0.0017 18.4 0.0 12.8 15 0 0 15 15 15 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 CBZ30846.1 - 1.1e-11 44.0 0.0 0.12 11.8 0.0 6.4 5 0 0 5 5 5 3 PPR repeat TPR_19 PF14559.1 CBZ30846.1 - 0.00037 20.7 1.1 1.2 9.5 0.0 4.9 5 1 1 6 6 6 1 Tetratricopeptide repeat DENN PF02141.16 CBZ30847.1 - 7.2e-25 87.7 0.2 1.2e-24 87.0 0.2 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 CBZ30847.1 - 0.044 13.7 0.0 0.095 12.6 0.0 1.6 1 0 0 1 1 1 0 uDENN domain TPR_14 PF13428.1 CBZ30848.1 - 0.0013 19.1 4.7 0.087 13.4 0.2 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ30848.1 - 0.0018 17.8 1.3 0.02 14.5 0.5 2.4 1 1 1 2 2 2 2 TPR repeat YceG PF02618.11 CBZ30848.1 - 0.0074 15.3 0.2 0.18 10.7 0.0 2.1 2 0 0 2 2 2 1 YceG-like family TPR_2 PF07719.12 CBZ30848.1 - 0.018 14.9 2.5 2.6 8.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ30848.1 - 0.022 15.1 0.6 0.068 13.5 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ30848.1 - 0.055 14.1 2.3 0.24 12.1 1.5 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat Alpha_adaptin_C PF02296.11 CBZ30848.1 - 0.14 12.1 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain TPR_1 PF00515.23 CBZ30848.1 - 0.3 10.7 1.6 14 5.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.26 CBZ30849.1 - 1.3e-21 76.0 1.0 1.3e-21 76.0 0.7 1.7 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 CBZ30849.1 - 1.3e-19 69.8 0.4 8.4e-17 60.8 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CBZ30849.1 - 5.3e-15 55.2 19.9 5.3e-15 55.2 13.8 1.7 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 CBZ30849.1 - 0.32 10.7 8.2 0.38 10.4 0.8 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 CBZ30849.1 - 0.38 11.1 10.6 0.81 10.0 7.3 1.6 1 0 0 1 1 1 0 Cytochrome c3 PADR1 PF08063.7 CBZ30849.1 - 6.6 6.2 11.0 3 7.3 1.0 2.9 1 1 2 3 3 3 0 PADR1 (NUC008) domain DNA_pol_A_exo1 PF01612.15 CBZ30850.1 - 6e-15 55.1 0.0 1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-CCHC PF00098.18 CBZ30850.1 - 0.0025 17.6 3.0 0.0025 17.6 2.1 4.5 4 1 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 CBZ30850.1 - 0.25 11.0 29.1 0.15 11.7 0.8 3.9 4 0 0 4 4 4 0 Zinc knuckle zf-C4_ClpX PF06689.8 CBZ30850.1 - 9.7 5.7 11.6 7.6 6.1 0.3 2.8 2 1 0 2 2 2 0 ClpX C4-type zinc finger Glyoxalase_2 PF12681.2 CBZ30852.1 - 1e-14 55.0 0.0 1.2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 CBZ30852.1 - 2.9e-14 53.1 0.1 3.8e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 CBZ30852.1 - 1.9e-09 37.5 0.0 3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 CBZ30852.1 - 0.0074 15.9 0.0 0.0098 15.5 0.0 1.3 1 1 0 1 1 1 1 CppA N-terminal PAF-AH_p_II PF03403.8 CBZ30853.1 - 1.4e-29 102.6 0.0 7.7e-29 100.1 0.0 1.9 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 CBZ30853.1 - 1.6e-10 40.9 0.0 2.6e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ30853.1 - 1.3e-09 38.3 0.2 2e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 CBZ30853.1 - 0.00023 20.1 0.0 0.0011 17.9 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 CBZ30853.1 - 0.02 14.4 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SNARE_assoc PF09335.6 CBZ30853.1 - 0.053 13.7 0.6 0.14 12.3 0.4 1.7 1 0 0 1 1 1 0 SNARE associated Golgi protein Lipase_3 PF01764.20 CBZ30853.1 - 0.095 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 CBZ30853.1 - 0.12 11.1 0.0 11 4.6 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase ICMT PF04140.9 CBZ30854.1 - 7.5e-20 70.9 2.4 7.5e-20 70.9 1.7 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CBZ30854.1 - 1.3e-08 34.9 1.6 1.3e-08 34.9 1.1 2.6 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 CBZ30854.1 - 0.00013 21.3 2.7 0.00013 21.3 1.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) DUF4293 PF14126.1 CBZ30854.1 - 0.32 10.8 2.7 0.59 10.0 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF2721 PF11026.3 CBZ30854.1 - 0.42 10.2 3.4 1.3 8.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RseC_MucC PF04246.7 CBZ30854.1 - 0.44 10.1 2.2 0.48 10.0 0.4 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PrgI PF12666.2 CBZ30854.1 - 0.9 9.7 4.4 0.36 10.9 0.7 2.0 2 0 0 2 2 2 0 PrgI family protein DUF3302 PF11742.3 CBZ30854.1 - 0.93 9.3 5.7 4.6 7.1 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3302) NDUFA12 PF05071.11 CBZ30855.1 - 2.8e-06 27.7 0.4 8e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 zf-CCHC_2 PF13696.1 CBZ30856.1 - 8.6e-05 21.9 4.9 8.6e-05 21.9 3.4 1.6 2 0 0 2 2 2 1 Zinc knuckle zf-RING_4 PF14570.1 CBZ30856.1 - 0.019 14.5 3.1 0.019 14.5 2.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 CBZ30856.1 - 0.053 13.3 2.7 0.14 11.9 1.9 1.7 1 0 0 1 1 1 0 Ring finger domain zf-CHY PF05495.7 CBZ30856.1 - 0.41 10.8 3.4 0.24 11.6 0.2 2.0 2 0 0 2 2 2 0 CHY zinc finger zf-RING_5 PF14634.1 CBZ30856.1 - 0.53 10.0 9.7 0.4 10.4 2.5 2.4 2 0 0 2 2 2 0 zinc-RING finger domain FYVE PF01363.16 CBZ30856.1 - 0.73 9.7 6.9 0.16 11.8 1.6 2.2 2 0 0 2 2 2 0 FYVE zinc finger TF_Zn_Ribbon PF08271.7 CBZ30856.1 - 0.97 8.8 5.9 0.51 9.6 0.7 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-CCHC PF00098.18 CBZ30856.1 - 1.1 9.2 9.6 0.084 12.8 3.1 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4_3 PF13920.1 CBZ30856.1 - 1.3 8.7 9.5 0.1 12.2 2.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_3 PF13917.1 CBZ30856.1 - 2.4 7.9 5.3 1.8 8.3 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-C3HC4_2 PF13923.1 CBZ30856.1 - 8.5 6.5 10.5 0.29 11.1 2.5 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ThiF PF00899.16 CBZ30857.1 - 2.9e-48 163.1 0.5 7.6e-34 116.4 0.2 2.4 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 CBZ30857.1 - 3.8e-27 93.6 3.3 2.2e-26 91.2 0.1 2.9 3 0 0 3 3 3 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CBZ30857.1 - 3.9e-16 58.1 0.0 7.3e-16 57.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site 3HCDH_N PF02737.13 CBZ30857.1 - 0.00098 18.8 0.2 0.0032 17.1 0.1 1.9 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mito_fiss_reg PF05308.6 CBZ30857.1 - 0.21 10.9 2.8 3 7.1 2.3 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator CrtC PF07143.6 CBZ30858.1 - 1.7e-06 27.5 0.2 1.8e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Hydroxyneurosporene synthase (CrtC) FGGY_N PF00370.16 CBZ30859.1 - 1.9e-66 223.8 0.0 2.5e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CBZ30859.1 - 5e-60 202.5 1.2 9.5e-60 201.6 0.9 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DnaJ PF00226.26 CBZ30860.1 - 3.9e-11 42.5 0.0 8.7e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DEAD PF00270.24 CBZ30861.1 - 3.3e-39 134.0 0.0 3.7e-37 127.4 0.0 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ30861.1 - 1.8e-26 91.7 0.2 3.7e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CBZ30861.1 - 0.006 16.5 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 CBZ30861.1 - 0.056 13.2 0.0 0.37 10.6 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit WD40 PF00400.27 CBZ30863.1 - 3.7 7.5 9.6 0.65 9.9 0.1 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Dynein_light PF01221.13 CBZ30864.1 - 4.7e-13 48.9 0.1 8.7e-13 48.0 0.1 1.4 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CBZ30864.1 - 0.006 16.8 0.0 0.012 15.8 0.0 1.6 1 1 0 1 1 1 1 Ground-like domain IPK PF03770.11 CBZ30865.1 - 1e-19 70.9 0.0 9.2e-19 67.8 0.0 2.1 1 1 0 1 1 1 1 Inositol polyphosphate kinase Flavokinase PF01687.12 CBZ30867.1 - 1.3e-27 96.1 0.0 1.7e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Riboflavin kinase DMA PF03474.9 CBZ30867.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif Pkinase PF00069.20 CBZ30868.1 - 1.3e-42 145.7 0.0 2.4e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30868.1 - 1.1e-17 63.9 0.0 2.4e-16 59.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ30868.1 - 2.9e-05 23.9 0.2 0.00034 20.4 0.1 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ30868.1 - 0.01 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 CBZ30868.1 - 0.02 13.9 0.0 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 CBZ30868.1 - 0.15 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 CBZ30868.1 - 0.95 8.9 0.0 1.8 8.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PBP1_TM PF14812.1 CBZ30869.1 - 0.86 9.9 7.0 0.31 11.3 2.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal His_Phos_1 PF00300.17 CBZ30870.1 - 2.4e-10 40.7 0.0 1.2e-09 38.4 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.17 CBZ30871.1 - 4.6e-08 32.5 0.0 4.1e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ30871.1 - 2.7e-05 24.0 0.0 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ30871.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_7 PF13499.1 CBZ30872.1 - 8.5e-10 38.6 0.4 1.1e-08 35.0 0.2 2.5 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ30872.1 - 0.002 17.3 5.6 0.044 13.1 0.1 3.6 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 CBZ30872.1 - 0.0071 16.1 2.1 0.081 12.8 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 CBZ30872.1 - 0.043 13.1 0.9 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 CBZ30872.1 - 0.069 12.7 5.2 2.3 7.8 0.1 3.0 3 0 0 3 3 3 0 EF-hand domain pair CAP_N PF01213.14 CBZ30873.1 - 6.1 6.0 6.5 4.1 6.5 3.3 1.6 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cys_Met_Meta_PP PF01053.15 CBZ30874.1 - 4.8e-127 423.4 0.1 5.5e-127 423.2 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CBZ30874.1 - 1.8e-07 30.5 1.6 2.7e-07 29.9 0.4 1.6 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CBZ30874.1 - 5.1e-05 22.5 0.5 9.6e-05 21.6 0.3 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CBZ30874.1 - 0.00028 19.7 0.1 0.00055 18.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 CBZ30874.1 - 0.06 11.8 0.1 0.088 11.2 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Pox_F11 PF04943.7 CBZ30875.1 - 0.15 10.8 1.1 0.31 9.8 0.7 1.6 1 0 0 1 1 1 0 Poxvirus F11 protein AAA PF00004.24 CBZ30876.1 - 3.9e-15 56.2 0.0 7.6e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CBZ30876.1 - 1.4e-12 47.1 0.0 1.6e-10 40.2 0.0 2.1 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta2 PF13177.1 CBZ30876.1 - 8.2e-11 41.8 0.0 1.4e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CBZ30876.1 - 3.3e-07 30.1 0.0 2e-06 27.7 0.0 2.2 3 0 0 3 3 2 1 Replication factor C C-terminal domain AAA_22 PF13401.1 CBZ30876.1 - 4.5e-07 30.0 0.0 2.8e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CBZ30876.1 - 7.2e-07 28.8 0.0 1.7e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 CBZ30876.1 - 2.1e-06 27.0 0.0 3.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 CBZ30876.1 - 2.6e-06 27.1 0.0 6.5e-06 25.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CBZ30876.1 - 4.5e-06 26.5 0.0 8.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ30876.1 - 5.9e-06 26.3 0.0 4.9e-05 23.3 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CBZ30876.1 - 4.1e-05 23.3 0.0 0.00012 21.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 CBZ30876.1 - 7e-05 22.5 0.0 0.0024 17.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.1 CBZ30876.1 - 0.00027 21.3 0.0 0.00038 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CBZ30876.1 - 0.00029 19.9 0.0 0.00055 19.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 CBZ30876.1 - 0.00054 19.4 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CBZ30876.1 - 0.0025 17.5 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 CBZ30876.1 - 0.0029 17.4 0.0 0.0072 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CBZ30876.1 - 0.0031 17.1 0.0 0.018 14.6 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CBZ30876.1 - 0.0041 16.0 0.0 0.41 9.4 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activat PF00158.21 CBZ30876.1 - 0.0058 16.1 0.0 0.02 14.3 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.8 CBZ30876.1 - 0.006 15.5 0.0 0.0097 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 CBZ30876.1 - 0.0071 15.8 0.1 0.74 9.1 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain DUF2075 PF09848.4 CBZ30876.1 - 0.0099 14.8 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 CBZ30876.1 - 0.01 16.6 0.0 0.028 15.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CBZ30876.1 - 0.011 15.3 0.4 0.022 14.3 0.3 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CBZ30876.1 - 0.013 15.5 0.0 0.5 10.4 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 CBZ30876.1 - 0.027 13.9 0.0 0.063 12.7 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DEAD PF00270.24 CBZ30876.1 - 0.034 13.6 0.2 0.54 9.7 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.1 CBZ30876.1 - 0.036 13.4 0.0 0.089 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CBZ30876.1 - 0.043 13.2 0.0 0.87 8.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ArgK PF03308.11 CBZ30876.1 - 0.057 12.1 0.1 0.19 10.4 0.1 1.8 1 1 0 1 1 1 0 ArgK protein DSBA PF01323.15 CBZ30876.1 - 0.076 12.5 0.1 0.18 11.3 0.0 1.6 2 0 0 2 2 1 0 DSBA-like thioredoxin domain AAA_28 PF13521.1 CBZ30876.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CBZ30876.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CBZ30876.1 - 0.14 12.0 0.0 0.84 9.4 0.0 2.0 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Pex19 PF04614.7 CBZ30877.1 - 4.3e-14 52.7 27.8 2e-13 50.5 0.2 3.2 2 1 1 3 3 3 2 Pex19 protein family Psu PF07455.6 CBZ30877.1 - 0.031 13.7 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) PPR_2 PF13041.1 CBZ30877.1 - 0.16 11.9 0.2 0.54 10.2 0.2 2.0 1 0 0 1 1 1 0 PPR repeat family Ribosomal_L31e PF01198.14 CBZ30879.1 - 5.5e-28 96.4 0.4 5.5e-28 96.4 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L31e Ribosomal_L31e PF01198.14 CBZ30880.1 - 5.5e-28 96.4 0.4 5.5e-28 96.4 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L31e WD40 PF00400.27 CBZ30881.1 - 6.3e-06 25.8 11.2 5.7 6.9 0.0 6.0 5 1 0 5 5 5 4 WD domain, G-beta repeat LRR_4 PF12799.2 CBZ30882.1 - 1.9e-13 49.7 4.0 2.2e-07 30.3 0.4 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ30882.1 - 2e-08 33.8 8.0 4.3e-05 23.1 1.7 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 CBZ30882.1 - 1.1e-06 28.3 0.8 2.6e-05 23.8 0.0 2.0 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.1 CBZ30882.1 - 9.6e-06 25.1 1.3 0.39 10.9 0.0 4.5 2 1 2 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 CBZ30882.1 - 0.0012 18.5 5.7 1.5 9.1 0.0 4.4 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 CBZ30882.1 - 0.019 15.0 3.1 7 7.3 0.0 4.4 3 1 0 3 3 3 0 Leucine rich repeat TRAPP PF04051.11 CBZ30883.1 - 1.1e-27 96.4 0.0 1.3e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Mito_carr PF00153.22 CBZ30884.1 - 1.2e-54 181.9 0.3 1.8e-20 72.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein 6PGD PF00393.14 CBZ30885.1 - 4.1e-90 301.9 0.0 5.8e-90 301.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CBZ30885.1 - 2.4e-47 160.7 0.1 3.7e-47 160.1 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CBZ30885.1 - 2.7e-06 27.5 0.1 4.6e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 CBZ30885.1 - 4.4e-05 23.1 0.1 7.7e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CBZ30885.1 - 0.00021 21.6 0.2 0.00048 20.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 CBZ30885.1 - 0.00068 19.4 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 CBZ30885.1 - 0.0036 16.4 0.2 0.009 15.1 0.2 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 CBZ30885.1 - 0.0055 15.6 0.0 0.0081 15.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CBZ30885.1 - 0.016 15.0 0.1 0.036 13.9 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 CBZ30885.1 - 0.034 13.5 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA IlvN PF07991.7 CBZ30885.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TP_methylase PF00590.15 CBZ30886.1 - 1e-21 77.6 3.1 1.1e-20 74.3 0.0 2.9 2 2 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF2428 PF10350.4 CBZ30887.1 - 7.2e-55 185.7 0.0 1.9e-54 184.4 0.0 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 CBZ30887.1 - 0.0032 17.4 10.4 5.3 7.3 0.1 7.0 7 0 0 7 7 7 2 HEAT repeat RAP1 PF07218.6 CBZ30888.1 - 1.9 6.4 2.0 3.2 5.7 1.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PARP_regulatory PF01358.13 CBZ30889.1 - 2e-18 66.0 0.0 1.2e-10 40.5 0.0 2.5 2 1 0 2 2 2 2 Poly A polymerase regulatory subunit Sporozoite_P67 PF05642.6 CBZ30889.1 - 0.15 9.8 0.2 0.21 9.4 0.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC50 PF03381.10 CBZ30891.1 - 3.6e-87 292.0 0.0 6.9e-87 291.1 0.0 1.4 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family KRE9 PF05390.6 CBZ30891.1 - 0.092 13.1 1.0 0.29 11.4 0.7 1.8 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 Rep_fac-A_3 PF08661.6 CBZ30895.1 - 1.6e-08 34.4 0.0 2.6e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Replication factor A protein 3 BHD_3 PF10405.4 CBZ30896.1 - 8.1e-22 76.7 0.0 1.4e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 CBZ30896.1 - 4.6e-19 68.2 0.3 1.1e-18 66.9 0.2 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 CBZ30896.1 - 3.7e-12 45.5 0.0 6.9e-12 44.6 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CBZ30896.1 - 3.1e-09 37.0 1.5 5.7e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CBZ30896.1 - 0.56 10.4 4.5 6.6 6.9 0.1 3.9 3 1 0 4 4 4 0 Transglutaminase-like superfamily peroxidase PF00141.18 CBZ30897.1 - 3.3e-08 33.2 0.0 3.7e-08 33.1 0.0 1.2 1 1 0 1 1 1 1 Peroxidase Acyl_transf_1 PF00698.16 CBZ30898.1 - 9.2e-18 64.6 0.0 1.1e-16 61.1 0.0 2.6 2 2 1 3 3 3 1 Acyl transferase domain RdRP PF05183.7 CBZ30898.1 - 0.019 13.6 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase DUF1571 PF07608.6 CBZ30898.1 - 0.079 12.0 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1571) FYVE PF01363.16 CBZ30901.1 - 1.3e-19 69.8 8.0 1.9e-19 69.2 5.5 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 CBZ30901.1 - 0.9 9.4 4.3 1.5 8.7 3.0 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.6 CBZ30901.1 - 9 6.0 9.5 21 4.8 6.6 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SMC_N PF02463.14 CBZ30902.1 - 1.4e-55 187.9 0.0 9.4e-55 185.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CBZ30902.1 - 1.3e-27 96.1 0.0 6.2e-27 93.9 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CBZ30902.1 - 3.1e-13 50.3 0.0 3.9e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CBZ30902.1 - 2.5e-07 31.2 53.9 4.3e-06 27.2 20.3 5.1 2 2 1 3 3 2 1 AAA domain AAA_29 PF13555.1 CBZ30902.1 - 7.9e-07 28.5 0.0 1.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CBZ30902.1 - 0.0006 18.9 0.0 0.0069 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain OmpH PF03938.9 CBZ30902.1 - 0.0023 17.8 3.3 0.0023 17.8 2.3 7.8 4 2 0 5 5 3 1 Outer membrane protein (OmpH-like) DUF258 PF03193.11 CBZ30902.1 - 0.0035 16.5 0.0 0.013 14.7 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Reo_sigmaC PF04582.7 CBZ30902.1 - 0.011 14.9 17.6 0.2 10.8 0.5 4.4 4 0 0 4 4 4 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 CBZ30902.1 - 0.035 14.4 0.0 0.035 14.4 0.0 5.5 4 2 0 4 4 3 0 ABC transporter Baculo_PEP_C PF04513.7 CBZ30902.1 - 7.9 6.2 20.6 1 9.1 0.3 5.2 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus NIF PF03031.13 CBZ30903.1 - 6.8e-30 103.8 0.3 2.3e-29 102.1 0.0 2.0 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase KH_1 PF00013.24 CBZ30905.1 - 6.3e-07 28.9 1.3 2e-06 27.3 0.9 1.8 1 0 0 1 1 1 1 KH domain MxiH PF09392.5 CBZ30906.1 - 0.00072 20.0 0.5 0.2 12.2 0.0 3.2 2 2 0 2 2 2 1 Type III secretion needle MxiH like DUF2497 PF10691.4 CBZ30906.1 - 0.016 15.1 0.1 0.016 15.1 0.1 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF2497) Baculo_PEP_C PF04513.7 CBZ30906.1 - 0.61 9.9 6.1 0.71 9.6 0.7 2.9 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 CBZ30906.1 - 1.1 8.7 29.8 5.1 6.5 20.6 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain TBPIP PF07106.8 CBZ30906.1 - 2.6 7.5 10.8 3.4 7.1 5.6 2.4 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_13 PF13166.1 CBZ30906.1 - 2.6 6.3 8.6 4 5.7 6.0 1.1 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 CBZ30906.1 - 6.6 6.3 16.8 18 4.8 11.7 1.8 1 1 0 1 1 1 0 Mnd1 family Tho2 PF11262.3 CBZ30906.1 - 8.4 5.3 6.9 15 4.4 4.8 1.4 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 CRAL_TRIO PF00650.15 CBZ30907.1 - 2.5e-24 85.5 0.1 4e-24 84.9 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CBZ30907.1 - 5.7e-09 35.9 0.9 5.7e-09 35.9 0.6 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain FUSC_2 PF13515.1 CBZ30908.1 - 1e-07 31.9 4.0 1e-07 31.9 2.8 2.4 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 CBZ30908.1 - 9.9e-05 20.9 4.4 0.00025 19.6 3.1 1.7 1 0 0 1 1 1 1 Fusaric acid resistance protein family MatE PF01554.13 CBZ30909.1 - 1.1e-27 96.6 25.6 2.3e-15 56.5 7.6 2.3 2 0 0 2 2 2 2 MatE E1-E2_ATPase PF00122.15 CBZ30909.1 - 0.63 9.0 4.8 0.92 8.5 1.2 2.3 2 0 0 2 2 2 0 E1-E2 ATPase XPG_I_2 PF12813.2 CBZ30910.1 - 3.1e-35 121.8 0.0 4.7e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 CBZ30910.1 - 2e-21 75.8 0.3 3.7e-21 74.9 0.2 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CBZ30910.1 - 9.5e-20 70.7 0.0 2.6e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain Methyltransf_23 PF13489.1 CBZ30911.1 - 1.2e-24 86.8 0.0 2.2e-24 86.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ30911.1 - 0.0049 17.3 0.1 0.095 13.1 0.0 2.9 4 0 0 4 4 4 1 Methyltransferase domain Pro_isomerase PF00160.16 CBZ30912.1 - 2.3e-28 99.3 0.0 5.1e-28 98.2 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NifU_N PF01592.11 CBZ30913.1 - 1.5e-48 163.9 0.0 1.9e-48 163.5 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain MatE PF01554.13 CBZ30914.1 - 2.7e-32 111.6 32.2 7.2e-19 67.9 8.9 3.5 3 0 0 3 3 3 3 MatE TfuA PF07812.7 CBZ30914.1 - 0.071 12.5 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 TfuA-like protein FliX PF10768.4 CBZ30915.1 - 0.03 14.5 0.4 0.055 13.6 0.3 1.5 1 0 0 1 1 1 0 Class II flagellar assembly regulator NDUF_B7 PF05676.8 CBZ30918.1 - 2.1e-08 33.4 0.3 3.4e-08 32.7 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) PEX11 PF05648.9 CBZ30919.1 - 3.8e-08 32.8 0.0 4.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.9 CBZ30920.1 - 4.8e-14 52.1 0.0 1.2e-13 50.8 0.0 1.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4190 PF13828.1 CBZ30921.1 - 0.11 12.0 2.5 0.19 11.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) PhyH PF05721.8 CBZ30924.1 - 0.094 12.7 0.0 0.52 10.3 0.0 2.1 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Cullin PF00888.17 CBZ30925.1 - 2.7e-21 75.7 0.0 3.7e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family Antibiotic_NAT PF02522.9 CBZ30925.1 - 0.012 14.8 0.1 0.028 13.6 0.0 1.6 2 0 0 2 2 2 0 Aminoglycoside 3-N-acetyltransferase Ank PF00023.25 CBZ30925.1 - 0.06 13.1 0.0 0.79 9.6 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.1 CBZ30925.1 - 0.15 12.3 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat Ribosomal_L18e PF00828.14 CBZ30926.1 - 1.3e-32 112.9 0.8 1.5e-32 112.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L18e PF00828.14 CBZ30928.1 - 1.3e-32 112.9 0.8 1.5e-32 112.6 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_L14 PF00238.14 CBZ30929.1 - 1e-36 125.3 0.0 1.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Ribosomal_L14 PF00238.14 CBZ30930.1 - 1e-36 125.3 0.0 1.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cep57_CLD_2 PF14197.1 CBZ30932.1 - 0.027 14.4 2.0 0.027 14.4 1.4 3.8 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 Cucumo_2B PF03263.8 CBZ30932.1 - 0.19 12.0 0.2 0.19 12.0 0.2 2.9 3 0 0 3 3 3 0 Cucumovirus protein 2B DUF4140 PF13600.1 CBZ30932.1 - 3.7 8.0 18.1 21 5.6 0.6 3.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Fmp27_WPPW PF10359.4 CBZ30932.1 - 6.2 5.1 8.7 98 1.1 6.1 2.3 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain SET PF00856.23 CBZ30933.1 - 0.003 17.8 0.0 0.055 13.7 0.0 2.2 1 1 0 1 1 1 1 SET domain Proteasome PF00227.21 CBZ30934.1 - 9.8e-48 161.9 0.3 1.2e-47 161.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CBZ30934.1 - 0.0017 17.5 0.1 0.0017 17.5 0.1 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal DUF1375 PF07119.7 CBZ30934.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1375) Ribosomal_S17 PF00366.15 CBZ30935.1 - 3.2e-14 52.7 0.4 3.2e-14 52.7 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 Cpn60_TCP1 PF00118.19 CBZ30936.1 - 5.6e-149 496.8 2.1 6.5e-149 496.6 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NDK PF00334.14 CBZ30937.1 - 5.8e-30 103.8 0.0 3.8e-27 94.7 0.0 2.4 2 1 0 2 2 2 2 Nucleoside diphosphate kinase V_ATPase_I PF01496.14 CBZ30937.1 - 0.19 9.5 0.0 0.25 9.1 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 CBZ30938.1 - 2.8e-41 137.9 18.4 8.7e-11 41.2 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 CBZ30938.1 - 1.4e-09 37.8 6.1 2.9e-09 36.8 4.2 1.5 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 CBZ30938.1 - 0.00072 19.3 0.1 0.0049 16.6 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBZ30938.1 - 0.046 11.8 2.1 4.5 5.2 0.1 3.0 2 2 1 3 3 3 0 Nucleoporin Nup120/160 EF-hand_7 PF13499.1 CBZ30939.1 - 4.6e-11 42.6 0.3 4.8e-09 36.2 0.4 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CBZ30939.1 - 1.3e-09 36.6 2.1 2.9e-08 32.4 0.0 3.6 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.1 CBZ30939.1 - 5.3e-09 35.2 0.1 8.8e-06 25.1 0.0 3.3 3 1 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 CBZ30939.1 - 2.1e-08 33.6 1.4 0.0021 17.6 0.1 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 CBZ30939.1 - 4e-05 22.7 0.0 4e-05 22.7 0.0 2.4 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 CBZ30939.1 - 0.0028 17.5 0.0 0.44 10.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain UPF0154 PF03672.8 CBZ30939.1 - 0.008 15.7 0.0 0.3 10.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) Baculo_p48 PF04878.8 CBZ30939.1 - 0.11 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Baculovirus P48 protein DUF282 PF03380.9 CBZ30942.1 - 0.018 14.7 2.1 0.044 13.5 1.5 1.7 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 SHIPPO-rpt PF07004.7 CBZ30943.1 - 4.9e-13 49.2 51.6 0.06 14.2 2.8 10.4 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat UNC-50 PF05216.8 CBZ30944.1 - 1.7e-62 210.6 7.0 2e-62 210.4 4.8 1.0 1 0 0 1 1 1 1 UNC-50 family DUF106 PF01956.11 CBZ30944.1 - 0.23 10.9 5.5 0.051 13.0 1.1 1.9 2 1 0 2 2 2 0 Integral membrane protein DUF106 INCENP_N PF12178.3 CBZ30945.1 - 1.2e-16 59.9 0.3 2.3e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 Chromosome passenger complex (CPC) protein INCENP N terminal PROCN PF08083.6 CBZ30946.1 - 2.5e-167 556.5 1.2 6.7e-167 555.0 0.8 1.7 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CBZ30946.1 - 1.7e-94 315.4 0.0 2.7e-94 314.8 0.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CBZ30946.1 - 1.7e-70 235.4 0.0 4.4e-70 234.1 0.0 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CBZ30946.1 - 1.1e-59 200.4 0.0 3.5e-59 198.8 0.0 2.0 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CBZ30946.1 - 9.6e-57 190.3 0.1 2.1e-56 189.2 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 CBZ30946.1 - 4.5e-37 126.5 0.0 1e-36 125.4 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 CBZ30946.1 - 1.9e-36 123.8 0.1 4.9e-36 122.4 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Pkinase PF00069.20 CBZ30947.1 - 1.4e-68 230.9 0.0 1.6e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30947.1 - 2.1e-32 112.1 0.0 2.7e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ30947.1 - 7.5e-05 21.8 0.0 9.2e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CBZ30947.1 - 0.0071 16.8 0.2 0.013 15.9 0.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain POR PF01558.13 CBZ30947.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase zf-MIZ PF02891.15 CBZ30948.1 - 3.2e-19 68.1 1.5 6.7e-19 67.1 1.0 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CBZ30948.1 - 0.00038 19.8 0.1 0.0009 18.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Mito_carr PF00153.22 CBZ30950.1 - 1.5e-42 143.2 0.7 1.8e-21 75.6 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein HECT PF00632.20 CBZ30951.1 - 1.2e-54 185.6 0.0 2.3e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.20 CBZ30951.1 - 2.7e-49 167.6 0.0 5.1e-49 166.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30951.1 - 7.6e-30 103.8 0.0 1.6e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_11 PF13414.1 CBZ30951.1 - 1.3e-18 66.4 3.7 2.9e-15 55.6 0.8 2.8 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 CBZ30951.1 - 3.3e-13 48.6 2.3 4.8e-06 25.9 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ30951.1 - 5.9e-13 47.6 4.0 2.7e-05 23.7 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ30951.1 - 9.8e-08 31.2 1.6 0.33 10.8 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat Kinase-like PF14531.1 CBZ30951.1 - 1e-05 24.6 0.0 2.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Kinase-like TPR_17 PF13431.1 CBZ30951.1 - 0.00012 22.0 0.8 0.074 13.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ30951.1 - 0.0002 21.7 5.1 0.18 12.5 0.0 4.4 4 0 0 4 4 2 2 Tetratricopeptide repeat APH PF01636.18 CBZ30951.1 - 0.00044 20.0 0.0 0.00044 20.0 0.0 2.5 2 1 0 2 2 1 1 Phosphotransferase enzyme family TPR_16 PF13432.1 CBZ30951.1 - 0.0009 19.8 8.0 0.016 15.8 0.0 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ30951.1 - 0.0024 17.5 4.0 0.02 14.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat RIO1 PF01163.17 CBZ30951.1 - 0.0037 16.6 0.0 0.011 15.0 0.0 1.8 1 0 0 1 1 1 1 RIO1 family EMP24_GP25L PF01105.19 CBZ30951.1 - 0.013 15.2 2.2 0.021 14.5 0.7 1.8 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD tRNA-synt_2c PF01411.14 CBZ30951.1 - 0.025 12.8 4.2 0.046 12.0 2.9 1.4 1 0 0 1 1 1 0 tRNA synthetases class II (A) TPR_19 PF14559.1 CBZ30951.1 - 0.031 14.6 9.5 0.23 11.8 0.0 4.2 4 1 1 5 5 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ30951.1 - 0.034 14.6 0.2 2.4 8.8 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ30951.1 - 4.1 7.4 16.7 1.1 9.2 0.1 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.20 CBZ30952.1 - 6.1e-69 232.0 0.0 7.1e-69 231.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30952.1 - 1.4e-32 112.7 0.0 1.9e-32 112.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ30952.1 - 6.4e-05 22.0 0.0 8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 CBZ30952.1 - 0.017 15.6 0.4 0.039 14.4 0.3 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain POR PF01558.13 CBZ30952.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Abhydrolase_5 PF12695.2 CBZ30953.1 - 2.7e-23 82.3 0.0 1.1e-22 80.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CBZ30953.1 - 1.3e-16 61.1 0.1 5.7e-16 59.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ30953.1 - 2.8e-06 27.0 0.0 0.0039 16.7 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CBZ30953.1 - 2.9e-06 26.6 0.0 2.2e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 CBZ30953.1 - 3.4e-06 26.7 0.1 5.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CBZ30953.1 - 3.9e-06 26.4 0.0 0.011 15.2 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.7 CBZ30953.1 - 0.00027 19.5 0.1 0.0069 14.9 0.0 2.3 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 CBZ30953.1 - 0.00027 20.6 0.0 0.00063 19.5 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 CBZ30953.1 - 0.0008 18.7 0.0 0.057 12.6 0.0 2.1 1 1 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 CBZ30953.1 - 0.0036 17.1 0.0 0.012 15.4 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S15 PF02129.13 CBZ30953.1 - 0.0047 16.3 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.7 CBZ30953.1 - 0.013 14.3 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF1100 PF06500.6 CBZ30953.1 - 0.034 12.7 0.0 0.042 12.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) FSH1 PF03959.8 CBZ30953.1 - 0.051 13.0 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) UPF0227 PF05728.7 CBZ30953.1 - 0.073 12.7 0.0 0.19 11.4 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) IncA PF04156.9 CBZ30953.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 IncA protein PGAP1 PF07819.8 CBZ30953.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DEAD PF00270.24 CBZ30954.1 - 9.9e-35 119.5 0.0 4.7e-34 117.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CBZ30954.1 - 1e-21 76.5 0.0 4.2e-21 74.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CBZ30954.1 - 3.3e-16 58.5 0.0 8e-16 57.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CBZ30954.1 - 1.7e-05 24.7 0.0 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ PF00226.26 CBZ30955.1 - 4.3e-16 58.3 0.1 5.5e-15 54.8 0.0 2.4 1 1 0 1 1 1 1 DnaJ domain Nrf1_activ_bdg PF10492.4 CBZ30955.1 - 2.2 8.7 6.3 9.8 6.7 2.2 2.3 2 0 0 2 2 2 0 Nrf1 activator activation site binding domain Pkinase PF00069.20 CBZ30957.1 - 1.3e-39 135.9 0.0 3.4e-39 134.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ30957.1 - 2.8e-21 75.7 0.0 9.5e-21 74.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ30957.1 - 1.5e-09 37.2 0.0 3.1e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CBZ30957.1 - 0.61 8.8 0.0 0.98 8.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-RING_4 PF14570.1 CBZ30957.1 - 6.1 6.5 17.2 10 5.7 12.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RIIa PF02197.12 CBZ30958.1 - 5e-11 41.8 0.0 1.6e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit EF-hand_7 PF13499.1 CBZ30958.1 - 4.8e-05 23.4 0.0 0.00068 19.7 0.0 2.4 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 CBZ30958.1 - 0.00012 21.6 0.9 0.39 10.7 0.0 3.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 CBZ30958.1 - 0.0033 16.5 0.1 1.4 8.3 0.0 3.2 3 0 0 3 3 3 2 EF hand TPR_11 PF13414.1 CBZ30959.1 - 5.7e-16 57.9 12.3 5.9e-06 25.8 0.5 4.7 4 1 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 CBZ30959.1 - 2.7e-14 51.8 13.3 0.0049 16.6 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ30959.1 - 2.8e-14 53.2 10.8 0.00055 20.2 0.0 4.8 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ30959.1 - 3.5e-10 40.2 18.0 0.00018 22.1 0.4 4.6 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CBZ30959.1 - 8.4e-09 35.3 19.4 0.00016 22.0 0.3 6.7 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ30959.1 - 4.7e-08 32.8 19.5 0.043 13.7 0.1 5.7 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ30959.1 - 9.8e-06 24.9 12.3 1.5 8.5 0.9 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CBZ30959.1 - 1.3e-05 25.3 12.4 0.098 13.1 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ30959.1 - 3e-05 23.8 9.5 0.67 10.3 0.0 5.1 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 CBZ30959.1 - 0.00013 21.1 5.7 0.018 14.0 0.4 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ30959.1 - 0.00031 20.2 15.5 0.022 14.5 0.1 5.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ30959.1 - 0.001 18.6 4.7 9.1 6.3 1.2 5.9 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 CBZ30959.1 - 0.0065 16.7 16.1 0.088 13.2 0.2 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat NODP PF07684.7 CBZ30959.1 - 0.035 13.6 0.1 7 6.3 0.0 2.5 2 0 0 2 2 2 0 NOTCH protein MIT PF04212.13 CBZ30959.1 - 0.069 13.0 0.6 0.069 13.0 0.4 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain CbiX PF01903.12 CBZ30959.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 CbiX Alkyl_sulf_dimr PF14863.1 CBZ30959.1 - 0.08 13.1 0.6 0.08 13.1 0.4 2.6 1 1 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_21 PF09976.4 CBZ30959.1 - 1.5 8.7 12.4 1.2 9.1 0.6 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat SF3b10 PF07189.6 CBZ30961.1 - 4e-16 58.5 0.0 4.5e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) SseB PF07179.7 CBZ30962.1 - 0.0008 19.2 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 2 SseB protein N-terminal domain HD_3 PF13023.1 CBZ30963.1 - 2e-36 125.2 0.0 2.5e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 CBZ30963.1 - 5.9e-06 26.2 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 HD domain RRM_1 PF00076.17 CBZ30966.1 - 2.6e-73 241.6 0.0 7.9e-18 63.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ30966.1 - 2.3e-50 168.4 0.0 2.3e-12 46.6 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CBZ30966.1 - 2.4e-28 97.5 0.2 4.5e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.1 CBZ30966.1 - 3.9e-25 87.4 0.0 2.5e-07 30.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CBZ30966.1 - 2.1e-08 33.9 3.9 0.46 10.3 0.2 4.4 3 1 1 4 4 4 4 RNA binding motif Nup35_RRM_2 PF14605.1 CBZ30966.1 - 5.6e-06 26.0 0.0 0.24 11.1 0.0 4.1 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBZ30966.1 - 0.022 14.4 2.8 0.65 9.7 0.0 3.6 2 1 1 3 3 3 0 Limkain b1 FliG_M PF14841.1 CBZ30966.1 - 0.072 13.1 0.1 10 6.2 0.0 2.6 1 1 1 2 2 2 0 FliG middle domain TB2_DP1_HVA22 PF03134.14 CBZ30967.1 - 0.5 10.1 3.3 0.37 10.5 0.7 1.9 2 0 0 2 2 2 0 TB2/DP1, HVA22 family GTP_EFTU PF00009.22 CBZ30968.1 - 1.3e-42 145.4 0.1 5.6e-41 140.0 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CBZ30968.1 - 9.1e-08 32.1 0.0 2e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 CBZ30968.1 - 0.003 17.4 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CBZ30968.1 - 0.014 15.4 0.1 0.038 14.1 0.1 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 2 FeoB_N PF02421.13 CBZ30968.1 - 0.068 12.4 0.3 0.4 9.9 0.0 2.4 3 1 0 3 3 3 0 Ferrous iron transport protein B UBA PF00627.26 CBZ30968.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Herpes_capsid PF06112.6 CBZ30968.1 - 3.2 7.7 6.6 1.1 9.3 1.1 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF2009 PF09418.5 CBZ30969.1 - 2.3e-211 702.4 0.1 2.6e-211 702.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) RNA_pol_Rpc4 PF05132.9 CBZ30970.1 - 9e-07 28.9 0.0 2.9e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase III RPC4 BBS1 PF14779.1 CBZ30971.1 - 6.2e-59 199.0 0.0 1.6e-58 197.7 0.0 1.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.1 CBZ30971.1 - 0.0018 17.2 0.0 0.017 14.1 0.0 2.3 2 1 1 3 3 3 1 PTHB1 N-terminus PQQ_3 PF13570.1 CBZ30971.1 - 0.15 12.3 3.4 1.1e+02 3.2 0.0 4.5 4 0 0 4 4 4 0 PQQ-like domain DUF3639 PF12341.3 CBZ30971.1 - 0.25 11.3 1.9 13 5.8 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3639) VMA21 PF09446.5 CBZ30972.1 - 0.0048 16.7 4.0 0.0088 15.9 2.8 1.4 1 0 0 1 1 1 1 VMA21-like domain PMP22_Claudin PF00822.15 CBZ30972.1 - 0.025 14.2 0.2 0.037 13.6 0.2 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF3123 PF11321.3 CBZ30972.1 - 0.23 11.7 5.5 5.2 7.3 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) DUF4463 PF14703.1 CBZ30973.1 - 0.038 14.5 0.1 20 5.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Syja_N PF02383.13 CBZ30976.1 - 3.7e-26 91.6 0.0 2.6e-25 88.8 0.0 2.0 1 1 0 1 1 1 1 SacI homology domain PPR_2 PF13041.1 CBZ30977.1 - 0.078 12.9 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 PPR repeat family Methyltransf_23 PF13489.1 CBZ30978.1 - 8e-24 84.1 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ30978.1 - 7.1e-19 67.8 0.0 3.8e-18 65.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CBZ30978.1 - 1.9e-17 63.5 0.0 3.2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ30978.1 - 1.9e-13 50.6 0.0 4.6e-13 49.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ30978.1 - 5.1e-13 49.5 0.0 8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CBZ30978.1 - 2.4e-10 40.4 0.0 4.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CBZ30978.1 - 2.9e-09 37.1 0.0 5.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CBZ30978.1 - 2.6e-07 30.0 0.0 7.8e-07 28.4 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 CBZ30978.1 - 2.4e-06 26.9 0.0 3.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.11 CBZ30978.1 - 4e-06 25.9 0.0 6.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_32 PF13679.1 CBZ30978.1 - 5.8e-06 26.0 0.0 8.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 CBZ30978.1 - 8.1e-06 25.3 0.4 6e-05 22.5 0.2 1.9 1 1 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 CBZ30978.1 - 5.5e-05 22.6 0.2 0.00011 21.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 CBZ30978.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 CBZ30978.1 - 0.0014 17.7 0.0 0.0034 16.5 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 CBZ30978.1 - 0.004 16.5 0.4 0.14 11.5 0.1 2.3 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW TehB PF03848.9 CBZ30978.1 - 0.013 14.7 0.0 0.033 13.3 0.0 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB TPMT PF05724.6 CBZ30978.1 - 0.034 13.5 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) RrnaAD PF00398.15 CBZ30978.1 - 0.039 12.9 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FYVE PF01363.16 CBZ30979.1 - 2.8e-16 59.1 7.8 2.8e-16 59.1 5.4 2.7 2 1 0 2 2 2 1 FYVE zinc finger MIP-T3 PF10243.4 CBZ30979.1 - 0.012 14.0 36.0 0.015 13.7 24.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF3584 PF12128.3 CBZ30979.1 - 4.8 4.3 42.0 6.1 4.0 29.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAGA_bind PF06217.7 CBZ30979.1 - 7.9 6.3 22.5 12 5.7 15.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Asp-B-Hydro_N PF05279.6 CBZ30979.1 - 8.6 6.1 38.8 12 5.6 26.9 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4207 PF13904.1 CBZ30979.1 - 9.2 5.5 42.4 13 5.0 29.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) bZIP_1 PF00170.16 CBZ30981.1 - 0.017 15.0 24.5 0.43 10.5 4.7 5.1 4 1 0 4 4 4 0 bZIP transcription factor Toxin_51 PF15531.1 CBZ30981.1 - 0.043 13.6 0.5 0.23 11.2 0.3 2.3 1 0 0 1 1 1 0 Putative toxin 51 DUF948 PF06103.6 CBZ30981.1 - 0.34 10.8 14.3 0.26 11.1 1.0 3.3 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.4 CBZ30981.1 - 2 8.2 52.6 0.37 10.6 1.3 4.0 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 CBZ30981.1 - 2 7.5 53.1 0.083 12.0 9.7 4.4 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 CBZ30981.1 - 4.5 6.3 13.4 0.73 8.9 4.2 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Selenoprotein_S PF06936.6 CBZ30982.1 - 0.087 12.3 0.3 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Selenoprotein S (SelS) Claudin_2 PF13903.1 CBZ30984.1 - 0.028 14.1 2.1 0.081 12.6 1.4 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF2721 PF11026.3 CBZ30984.1 - 6.4 6.4 7.4 0.94 9.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Hydrolase_6 PF13344.1 CBZ30985.1 - 3.8e-23 81.2 0.0 7.2e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CBZ30985.1 - 5.6e-13 48.3 0.0 1.4e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 CBZ30985.1 - 0.0028 17.9 0.1 0.9 9.7 0.0 2.9 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CBZ30985.1 - 0.0063 16.9 0.0 2.9 8.2 0.0 2.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF4121 PF13497.1 CBZ30985.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) PIH1 PF08190.7 CBZ30986.1 - 1.5e-117 392.6 0.0 1.5e-117 392.6 0.0 1.9 3 0 0 3 3 3 1 pre-RNA processing PIH1/Nop17 HARE-HTH PF05066.8 CBZ30987.1 - 0.022 15.1 0.1 0.11 12.8 0.0 2.2 2 1 0 2 2 2 0 HB1, ASXL, restriction endonuclease HTH domain PGAP1 PF07819.8 CBZ30988.1 - 9.1e-13 48.3 0.0 1.8e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 PGAP1-like protein Abhydrolase_6 PF12697.2 CBZ30988.1 - 5.5e-06 26.4 0.7 0.00017 21.5 0.2 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CBZ30988.1 - 0.083 12.6 0.0 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CBZ30988.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4326 PF14216.1 CBZ30988.1 - 0.21 12.1 0.2 6.8 7.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) DUF1744 PF08490.7 CBZ30989.1 - 5.9e-49 166.6 0.0 5.5e-48 163.5 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CBZ30989.1 - 4.4e-48 163.8 0.1 7.4e-48 163.0 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CBZ30989.1 - 2.4e-19 69.4 0.0 3.4e-16 59.1 0.0 2.9 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CBZ30989.1 - 6.8e-09 35.5 3.3 2.2e-08 33.8 0.3 2.7 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CBZ30989.1 - 2.2e-08 34.1 0.3 1.1e-07 31.7 0.1 2.3 2 1 0 2 2 2 1 RNase_H superfamily zf-DNA_Pol PF08996.5 CBZ30989.1 - 0.00081 18.8 2.5 0.0023 17.3 1.8 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger zf-3CxxC PF13695.1 CBZ30990.1 - 2.7e-09 37.1 3.0 3.2e-09 36.8 2.1 1.1 1 0 0 1 1 1 1 Zinc-binding domain zinc_ribbon_4 PF13717.1 CBZ30990.1 - 0.0041 16.7 0.6 0.0041 16.7 0.4 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CBZ30990.1 - 0.0042 16.6 0.5 0.0042 16.6 0.3 2.2 2 0 0 2 2 2 1 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 CBZ30990.1 - 0.014 15.1 0.9 0.43 10.4 0.1 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-DNA_Pol PF08996.5 CBZ30990.1 - 0.042 13.2 0.5 0.056 12.8 0.3 1.1 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger Elf1 PF05129.8 CBZ30990.1 - 0.067 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-dskA_traR PF01258.12 CBZ30990.1 - 0.48 10.2 3.2 2 8.2 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger C1_3 PF07649.7 CBZ30990.1 - 0.73 9.9 2.7 17 5.5 0.3 2.3 2 0 0 2 2 2 0 C1-like domain HC2 PF07382.6 CBZ30991.1 - 1.4e-09 38.1 55.2 0.00013 21.8 22.0 3.6 1 1 2 3 3 3 3 Histone H1-like nucleoprotein HC2 LisH PF08513.6 CBZ30991.1 - 0.14 11.9 0.3 0.2 11.4 0.2 1.2 1 0 0 1 1 1 0 LisH TPR_12 PF13424.1 CBZ30992.1 - 7e-05 22.6 10.0 0.15 12.0 1.3 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CBZ30992.1 - 0.6 9.7 5.4 27 4.4 0.0 3.5 3 0 0 3 3 3 0 TPR repeat Snf7 PF03357.16 CBZ30993.1 - 2.4e-19 69.3 17.1 2.6e-19 69.2 11.6 1.3 1 1 0 1 1 1 1 Snf7 DUF3385 PF11865.3 CBZ30993.1 - 0.13 12.1 1.4 0.21 11.4 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) AA_permease_2 PF13520.1 CBZ30994.1 - 5.9e-38 130.4 40.8 7.7e-38 130.1 28.3 1.1 1 0 0 1 1 1 1 Amino acid permease Mito_carr PF00153.22 CBZ30995.1 - 2.6e-33 113.5 9.6 1.3e-18 66.4 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ArsB PF02040.10 CBZ30995.1 - 0.0022 17.0 0.7 0.0035 16.3 0.1 1.5 2 0 0 2 2 2 1 Arsenical pump membrane protein Asp_Arg_Hydrox PF05118.10 CBZ30996.1 - 0.049 13.4 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase PABP PF00658.13 CBZ30996.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Poly-adenylate binding protein, unique domain zf-CCCH PF00642.19 CBZ30997.1 - 0.63 9.7 3.2 1.1 9.0 2.2 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LSM PF01423.17 CBZ30998.1 - 1.1e-18 66.5 0.1 1.2e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CBZ30998.1 - 2.5e-05 24.1 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 CBZ30998.1 - 0.03 14.1 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain CS PF04969.11 CBZ30999.1 - 4.5e-10 39.9 0.1 6.1e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 CS domain ARL2_Bind_BART PF11527.3 CBZ31000.1 - 0.0028 17.4 0.3 0.0043 16.8 0.2 1.4 1 1 0 1 1 1 1 The ARF-like 2 binding protein BART Nic96 PF04097.9 CBZ31000.1 - 0.085 10.9 0.0 0.1 10.6 0.0 1.1 1 0 0 1 1 1 0 Nup93/Nic96 zf-Apc11 PF12861.2 CBZ31002.1 - 2e-28 98.0 10.3 2.1e-28 97.9 7.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CBZ31002.1 - 2.8e-25 88.2 11.4 3.1e-25 88.0 7.9 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CBZ31002.1 - 6.6e-08 32.2 20.7 5.9e-07 29.2 13.8 2.5 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 CBZ31002.1 - 4.8e-05 22.9 15.6 5.1e-05 22.8 9.9 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CBZ31002.1 - 0.00012 21.6 17.6 0.039 13.6 8.4 2.5 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CBZ31002.1 - 0.00031 20.7 16.3 0.0031 17.4 10.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CBZ31002.1 - 0.00098 18.8 18.7 0.0074 15.9 12.0 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 CBZ31002.1 - 0.0069 15.9 18.8 0.08 12.5 7.7 2.8 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CBZ31002.1 - 0.012 15.4 4.5 0.012 15.4 3.1 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HIT PF04438.11 CBZ31002.1 - 0.12 12.0 10.9 0.28 10.8 4.1 2.4 2 1 0 2 2 2 0 HIT zinc finger zf-Nse PF11789.3 CBZ31002.1 - 0.42 10.1 10.3 0.6 9.6 7.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H_2 PF13832.1 CBZ31002.1 - 1.4 8.9 9.5 2.2 8.3 6.6 1.5 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 CBZ31002.1 - 1.5 8.8 16.8 16 5.5 11.7 2.5 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 CBZ31002.1 - 1.8 8.3 14.8 24 4.7 10.2 2.4 1 1 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.1 CBZ31002.1 - 3.9 7.6 12.1 21 5.3 8.4 2.0 1 1 0 1 1 1 0 PHD-like zinc-binding domain DUF962 PF06127.6 CBZ31004.1 - 1.8e-21 75.8 4.2 3.7e-21 74.8 2.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) FPL PF09758.4 CBZ31006.1 - 1.6e-56 190.1 0.5 3e-56 189.3 0.4 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein SET PF00856.23 CBZ31007.1 - 7.7e-25 88.0 3.0 0.00052 20.3 0.0 9.7 11 0 0 11 11 11 5 SET domain SAF PF08666.7 CBZ31007.1 - 1.4e-06 28.5 0.0 56 4.2 0.0 9.6 11 1 0 11 11 11 1 SAF domain zf-HC5HC2H PF13771.1 CBZ31008.1 - 3.7e-14 52.6 4.6 8e-14 51.5 3.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CBZ31008.1 - 5.3e-07 29.6 8.2 9.7e-07 28.7 5.7 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain SseC PF04888.7 CBZ31009.1 - 0.025 13.8 3.3 0.037 13.3 2.3 1.3 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family 60KD_IMP PF02096.15 CBZ31010.1 - 5.4e-14 52.3 0.0 7.6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein PS_Dcarbxylase PF02666.10 CBZ31011.1 - 1.1e-38 132.6 0.0 1.3e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Collar PF07484.7 CBZ31011.1 - 0.097 12.4 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Phage Tail Collar Domain AAA_13 PF13166.1 CBZ31012.1 - 0.003 16.1 5.8 0.01 14.3 4.0 1.8 1 1 0 1 1 1 1 AAA domain Lebercilin PF15619.1 CBZ31012.1 - 0.0055 16.1 6.5 0.0055 16.1 4.5 5.0 5 1 0 5 5 5 1 Ciliary protein causing Leber congenital amaurosis disease DUF3762 PF12591.3 CBZ31012.1 - 0.054 13.5 0.1 0.18 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3762) Thioredoxin_4 PF13462.1 CBZ31012.1 - 0.41 10.6 5.0 0.28 11.1 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin TPR_MLP1_2 PF07926.7 CBZ31012.1 - 3.1 7.5 36.2 1.8 8.3 9.6 4.8 4 1 0 4 4 4 0 TPR/MLP1/MLP2-like protein DUF3675 PF12428.3 CBZ31012.1 - 5.6 7.2 7.1 0.62 10.3 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3675) Pkinase PF00069.20 CBZ31014.1 - 3.6e-09 36.1 0.0 2e-07 30.4 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ31014.1 - 0.01 14.9 0.0 0.031 13.3 0.0 1.7 2 1 0 2 2 2 0 Protein tyrosine kinase DnaJ PF00226.26 CBZ31015.1 - 1.7e-15 56.4 0.2 3.9e-15 55.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain EcoRII-C PF09019.6 CBZ31016.1 - 0.0054 16.5 3.8 0.0084 15.9 2.6 1.5 1 1 0 1 1 1 1 EcoRII C terminal Atg14 PF10186.4 CBZ31016.1 - 0.018 14.0 18.9 0.02 13.8 13.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 S1-P1_nuclease PF02265.11 CBZ31016.1 - 0.02 14.5 1.4 0.028 14.0 1.0 1.2 1 0 0 1 1 1 0 S1/P1 Nuclease Cgr1 PF03879.9 CBZ31016.1 - 0.041 14.0 24.9 0.047 13.8 17.2 1.1 1 0 0 1 1 1 0 Cgr1 family FAM178 PF14816.1 CBZ31016.1 - 0.096 11.3 4.8 0.11 11.2 3.4 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Med29 PF11568.3 CBZ31016.1 - 0.14 12.1 6.5 0.17 11.9 3.8 1.6 1 1 1 2 2 2 0 Mediator complex subunit 29 Glyco_transf_41 PF13844.1 CBZ31016.1 - 0.18 9.7 2.4 0.2 9.5 1.7 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 41 AKNA PF12443.3 CBZ31016.1 - 0.28 11.2 6.7 1.1 9.3 3.6 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor Baculo_LEF-11 PF06385.7 CBZ31016.1 - 0.34 11.0 8.2 3.2 7.9 0.7 2.1 1 1 1 2 2 2 0 Baculovirus LEF-11 protein DUF702 PF05142.7 CBZ31016.1 - 0.35 11.0 5.5 0.43 10.7 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Casc1 PF12366.3 CBZ31016.1 - 0.37 10.2 9.2 0.41 10.1 6.4 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 DUF2756 PF10956.3 CBZ31016.1 - 1.4 9.2 8.3 2.2 8.5 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Spore_coat_CotO PF14153.1 CBZ31016.1 - 3.3 7.1 14.6 3.8 6.9 10.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO NAM-associated PF14303.1 CBZ31016.1 - 4.5 7.5 20.8 5.6 7.2 14.4 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Asp-B-Hydro_N PF05279.6 CBZ31016.1 - 9.1 6.0 12.8 11 5.8 8.9 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ndc1_Nup PF09531.5 CBZ31016.1 - 9.8 4.4 7.0 11 4.3 4.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DSPc PF00782.15 CBZ31017.1 - 9.7e-19 67.2 0.0 1.4e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CBZ31017.1 - 0.0002 20.8 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CBZ31017.1 - 0.0067 16.6 0.0 0.045 13.9 0.0 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.7 CBZ31017.1 - 0.051 13.0 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.8 CBZ31017.1 - 0.093 12.0 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CBZ31017.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate zf-SNAP50_C PF12251.3 CBZ31018.1 - 5.7e-55 185.7 0.5 7.7e-55 185.3 0.4 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Katanin_con80 PF13925.1 CBZ31019.1 - 3.4e-40 137.4 0.0 4.6e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.27 CBZ31019.1 - 3.8e-28 96.3 7.8 8.2e-11 41.3 0.2 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 CBZ31019.1 - 0.0055 16.4 0.0 5.7 6.6 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CBZ31019.1 - 0.021 12.9 0.1 0.24 9.4 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF137 PF02006.11 CBZ31020.1 - 0.069 12.5 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF137 ParcG PF10274.4 CBZ31021.1 - 8.9e-76 253.8 0.0 1.1e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Kinesin PF00225.18 CBZ31022.1 - 2.5e-58 197.3 0.3 4.8e-58 196.4 0.2 1.4 1 1 0 1 1 1 1 Kinesin motor domain AAA_16 PF13191.1 CBZ31022.1 - 0.014 15.3 0.5 0.053 13.5 0.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain PhoH PF02562.11 CBZ31022.1 - 0.034 13.3 0.3 1.3 8.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF87 PF01935.12 CBZ31022.1 - 0.069 12.9 0.1 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2294 PF10057.4 CBZ31022.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) AAA_22 PF13401.1 CBZ31022.1 - 0.17 12.0 0.8 0.44 10.6 0.5 1.7 1 1 0 1 1 1 0 AAA domain HSP70 PF00012.15 CBZ31023.1 - 9.8e-63 212.0 0.0 1.8e-62 211.1 0.0 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CBZ31023.1 - 0.00077 18.1 0.0 0.0043 15.6 0.0 2.1 3 0 0 3 3 3 1 MreB/Mbl protein GCV_H PF01597.14 CBZ31024.1 - 1e-37 128.5 1.3 1.1e-37 128.4 0.9 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 CBZ31024.1 - 1.6e-07 30.8 1.1 2.4e-07 30.2 0.7 1.4 1 1 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 CBZ31024.1 - 0.00025 20.6 0.3 0.00033 20.3 0.2 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.15 CBZ31024.1 - 0.0025 17.3 0.1 0.0031 17.0 0.1 1.1 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Peptidase_M23 PF01551.17 CBZ31024.1 - 0.038 14.0 0.5 2.5 8.2 0.1 2.2 1 1 1 2 2 2 0 Peptidase family M23 MS_channel PF00924.13 CBZ31024.1 - 0.07 12.4 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel LURAP PF14854.1 CBZ31025.1 - 0.43 10.3 6.0 0.17 11.6 2.2 1.8 1 1 0 1 1 1 0 Leucine rich adaptor protein DUF4239 PF14023.1 CBZ31025.1 - 7.9 5.7 9.7 0.52 9.6 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) COG2 PF06148.6 CBZ31025.1 - 9.7 6.0 8.8 4.3 7.2 3.4 2.4 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Gp_dh_N PF00044.19 CBZ31026.1 - 7.2e-22 77.9 0.0 1.3e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.15 CBZ31026.1 - 1.6e-12 47.1 0.1 2.4e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain ADH_zinc_N PF00107.21 CBZ31026.1 - 0.013 15.0 0.3 0.12 11.9 0.0 2.3 2 1 0 2 2 2 0 Zinc-binding dehydrogenase DUF1761 PF08570.5 CBZ31027.1 - 0.0081 16.1 5.6 0.013 15.4 3.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1761) Phospholip_B PF04916.8 CBZ31027.1 - 0.075 11.1 0.0 0.095 10.7 0.0 1.1 1 0 0 1 1 1 0 Phospholipase B Pro_isomerase PF00160.16 CBZ31028.1 - 4.2e-44 150.4 0.2 7.5e-44 149.6 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CBZ31028.1 - 9.8e-16 57.1 9.3 2.3e-09 36.7 1.2 2.2 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CBZ31028.1 - 4.4e-09 35.5 3.3 0.004 16.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 CBZ31028.1 - 1e-07 31.2 2.2 0.0014 18.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ31028.1 - 6.2e-05 23.2 3.3 0.053 13.8 0.2 3.2 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CBZ31028.1 - 7.3e-05 22.6 2.8 0.037 13.9 0.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ31028.1 - 0.00026 21.5 2.0 0.006 17.2 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ31028.1 - 0.0013 18.7 4.3 0.0075 16.3 1.2 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CBZ31028.1 - 0.0018 18.6 0.7 9 7.0 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF1586 PF07625.6 CBZ31028.1 - 0.012 15.2 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) TPR_14 PF13428.1 CBZ31028.1 - 0.014 15.9 0.6 1 10.1 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ31028.1 - 0.015 15.1 0.1 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat SCAMP PF04144.8 CBZ31030.1 - 8e-49 165.9 10.5 9.7e-49 165.6 7.3 1.0 1 0 0 1 1 1 1 SCAMP family DUF1129 PF06570.6 CBZ31030.1 - 0.092 12.0 0.4 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) A_deaminase PF00962.17 CBZ31031.1 - 1.2e-104 349.8 0.0 1.9e-79 266.9 0.0 2.4 2 0 0 2 2 2 2 Adenosine/AMP deaminase HNOBA PF07701.9 CBZ31031.1 - 0.078 12.1 2.1 0.17 11.0 1.4 1.5 1 0 0 1 1 1 0 Heme NO binding associated BRCT PF00533.21 CBZ31032.1 - 1.2e-06 28.5 0.0 0.002 18.2 0.0 2.7 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain zf-ribbon_3 PF13248.1 CBZ31032.1 - 0.089 12.0 0.7 0.23 10.7 0.5 1.7 1 0 0 1 1 1 0 zinc-ribbon domain UPF0270 PF06794.7 CBZ31032.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) DZR PF12773.2 CBZ31032.1 - 1.4 8.7 6.1 7.3 6.4 4.2 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.13 CBZ31032.1 - 1.6 7.8 6.8 0.15 11.2 1.1 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others His_Phos_1 PF00300.17 CBZ31033.1 - 3.6e-13 49.8 0.0 1.1e-12 48.2 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UBA PF00627.26 CBZ31034.1 - 0.0026 17.5 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Radical_SAM PF04055.16 CBZ31034.1 - 0.014 15.5 0.0 0.066 13.3 0.0 2.0 2 1 0 2 2 2 0 Radical SAM superfamily Rap1_C PF11626.3 CBZ31034.1 - 0.036 13.9 0.2 0.33 10.8 0.1 2.6 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Proteasome PF00227.21 CBZ31036.1 - 1.4e-39 135.3 0.0 2e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CBZ31036.1 - 1.3e-11 43.5 0.2 1.3e-11 43.5 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Porin_3 PF01459.17 CBZ31037.1 - 0.078 12.2 1.8 0.11 11.7 1.2 1.3 1 0 0 1 1 1 0 Eukaryotic porin DUF2358 PF10184.4 CBZ31037.1 - 0.16 11.9 0.8 0.54 10.2 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2358) Baculo_PEP_C PF04513.7 CBZ31038.1 - 0.013 15.2 1.2 0.013 15.2 0.9 9.7 2 2 9 12 12 12 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_11 PF13414.1 CBZ31039.1 - 1.4e-20 72.7 14.9 7.5e-17 60.7 5.5 2.9 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CBZ31039.1 - 5.4e-15 54.2 14.1 1.3e-06 27.7 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CBZ31039.1 - 3.1e-11 42.2 22.2 4.4e-05 23.0 0.2 4.0 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CBZ31039.1 - 2.7e-06 27.1 5.5 1.1e-05 25.2 0.8 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat UPF0121 PF03661.8 CBZ31039.1 - 1.2e-05 24.6 8.9 1.6e-05 24.1 6.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_12 PF13424.1 CBZ31039.1 - 1.2e-05 25.1 10.3 0.0006 19.6 4.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CBZ31039.1 - 1.3e-05 24.5 12.3 0.035 13.8 2.2 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 CBZ31039.1 - 0.00011 22.7 1.9 0.00011 22.7 1.3 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CBZ31039.1 - 0.00029 21.1 4.4 0.008 16.4 0.6 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CBZ31039.1 - 0.0028 17.7 5.8 0.0028 17.7 4.0 2.1 2 0 0 2 2 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CBZ31039.1 - 0.021 15.3 8.2 3.4 8.5 0.5 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CBZ31039.1 - 0.035 13.9 2.6 7.6 6.5 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 CBZ31039.1 - 0.044 13.6 8.3 8.8 6.2 1.5 4.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CBZ31039.1 - 0.055 13.3 0.2 0.23 11.3 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 CBZ31039.1 - 0.73 9.7 7.8 0.15 11.9 0.4 2.9 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 CBZ31039.1 - 1.2 9.1 8.5 12 6.0 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Rad51 PF08423.6 CBZ31040.1 - 7.2e-135 447.8 0.1 1.1e-134 447.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 CBZ31040.1 - 1.8e-12 47.0 0.2 2.4e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 CBZ31040.1 - 4.9e-09 35.8 0.0 8.1e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 CBZ31040.1 - 2.2e-08 34.1 0.3 4.6e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 CBZ31040.1 - 1.2e-07 31.1 0.0 2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 KaiC Herpes_UL56 PF04534.7 CBZ31040.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL56 protein MCM PF00493.18 CBZ31042.1 - 4.2e-80 269.0 0.0 5.9e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family AAA_5 PF07728.9 CBZ31042.1 - 9.8e-05 22.1 0.0 0.001 18.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CBZ31042.1 - 0.0005 19.3 0.0 0.032 13.3 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CBZ31042.1 - 0.021 14.4 0.0 0.062 12.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF523 PF04463.7 CBZ31042.1 - 0.078 12.7 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF523) TTL PF03133.10 CBZ31043.1 - 1.5e-74 250.5 0.0 2.5e-74 249.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 CBZ31043.1 - 0.017 13.9 0.1 0.045 12.5 0.0 1.7 2 0 0 2 2 2 0 YheC/D like ATP-grasp DUF241 PF03087.9 CBZ31044.1 - 0.13 11.6 7.3 0.31 10.4 5.1 1.5 1 1 0 1 1 1 0 Arabidopsis protein of unknown function DUF3153 PF11353.3 CBZ31044.1 - 0.19 11.1 4.5 0.26 10.6 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Zip PF02535.17 CBZ31044.1 - 4.7 6.1 5.2 7.5 5.4 3.6 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter zf-CCCH PF00642.19 CBZ31045.1 - 0.0014 18.2 4.4 0.0025 17.4 3.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PAP2_C PF14360.1 CBZ31048.1 - 1.7e-20 73.0 7.1 1.7e-20 73.0 4.9 2.7 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PSP1 PF04468.7 CBZ31049.1 - 1.9e-15 56.5 1.8 3e-15 55.9 1.2 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PE_PPE_C PF12484.3 CBZ31049.1 - 0.055 14.3 5.2 0.1 13.5 3.6 1.5 1 0 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal Pkinase PF00069.20 CBZ31050.1 - 3.6e-68 229.5 0.0 4.4e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ31050.1 - 1.4e-29 102.9 0.0 5.5e-29 101.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ31050.1 - 3.1e-05 23.0 0.0 0.00011 21.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CBZ31050.1 - 0.019 14.6 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CBZ31050.1 - 0.047 12.5 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 CBZ31050.1 - 0.064 12.3 0.0 0.12 11.3 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.17 CBZ31053.1 - 4.9e-79 259.9 4.9 6.1e-21 73.8 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CBZ31053.1 - 1.7e-52 175.2 2.9 2e-15 56.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CBZ31053.1 - 1.9e-35 120.5 2.3 3.7e-10 39.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CBZ31053.1 - 4.7e-21 74.2 0.1 2.4e-19 68.7 0.0 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CBZ31053.1 - 1.2e-06 28.3 1.5 0.13 12.1 0.2 4.2 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.1 CBZ31053.1 - 0.0027 17.4 0.3 4 7.2 0.0 4.0 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CBZ31053.1 - 0.032 13.9 0.7 6.2 6.6 0.0 3.5 4 0 0 4 4 4 0 Limkain b1 Med23 PF11573.3 CBZ31054.1 - 0.51 7.6 0.0 0.67 7.2 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 23 EF-hand_6 PF13405.1 CBZ31056.1 - 0.15 11.9 1.3 0.19 11.6 0.1 1.8 2 0 0 2 2 2 0 EF-hand domain IFT57 PF10498.4 CBZ31057.1 - 0.02 13.6 1.5 0.022 13.4 1.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 GOLGA2L5 PF15070.1 CBZ31057.1 - 0.02 13.3 4.3 0.027 13.0 3.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Mod_r PF07200.8 CBZ31057.1 - 0.026 14.4 3.4 0.038 13.8 2.4 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein NYD-SP28_assoc PF14775.1 CBZ31057.1 - 0.029 14.0 4.4 0.031 13.9 0.7 2.6 2 1 2 4 4 4 0 Sperm tail C-terminal domain Seryl_tRNA_N PF02403.17 CBZ31057.1 - 0.035 14.1 0.7 0.051 13.5 0.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Mating_N PF12731.2 CBZ31057.1 - 0.038 13.8 0.4 4.3 7.2 0.0 3.0 2 1 1 4 4 4 0 Mating-type protein beta 1 Spc7 PF08317.6 CBZ31057.1 - 0.063 11.9 3.3 0.087 11.4 2.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.7 CBZ31057.1 - 0.067 12.9 1.6 0.12 12.1 1.1 1.5 1 0 0 1 1 1 0 Laminin Domain II Jnk-SapK_ap_N PF09744.4 CBZ31057.1 - 0.14 12.1 1.7 0.38 10.7 1.2 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Occludin_ELL PF07303.8 CBZ31057.1 - 0.17 12.6 1.7 0.53 11.0 1.2 1.8 1 1 0 1 1 1 0 Occludin homology domain M_domain PF12938.2 CBZ31057.1 - 1.5 8.5 6.2 2.2 8.0 4.3 1.2 1 0 0 1 1 1 0 M domain of GW182 RNase_Zc3h12a PF11977.3 CBZ31058.1 - 0.047 13.5 0.1 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain Ribosomal_L37e PF01907.14 CBZ31059.1 - 1.1e-22 79.6 8.0 1.8e-22 78.8 5.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e zinc_ribbon_6 PF14599.1 CBZ31059.1 - 0.046 13.5 0.6 0.07 12.9 0.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon DZR PF12773.2 CBZ31059.1 - 0.093 12.5 0.8 0.15 11.8 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon PseudoU_synth_2 PF00849.17 CBZ31060.1 - 7.5e-26 90.9 0.1 1.2e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase ALF PF03752.8 CBZ31060.1 - 0.012 15.4 2.2 0.042 13.7 1.5 2.0 1 0 0 1 1 1 0 Short repeats of unknown function Glycoprotein_B PF00606.13 CBZ31062.1 - 0.051 11.6 0.1 0.076 11.0 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B Methyltransf_11 PF08241.7 CBZ31063.1 - 3.7e-05 24.1 0.0 0.0012 19.2 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ31063.1 - 0.00044 20.6 0.0 0.0015 19.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ31063.1 - 0.00049 19.7 0.0 0.037 13.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CBZ31063.1 - 0.0011 18.7 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CBZ31063.1 - 0.0013 19.2 0.0 0.0039 17.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CBZ31063.1 - 0.14 11.2 0.0 0.33 10.0 0.0 1.5 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family BT1 PF03092.11 CBZ31064.1 - 6.8e-159 529.2 11.5 7.8e-159 529.0 7.9 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.11 CBZ31064.1 - 0.0016 17.2 14.4 0.0016 17.2 10.0 3.6 2 1 1 3 3 3 2 Major Facilitator Superfamily AAA_28 PF13521.1 CBZ31065.1 - 4.3e-05 23.5 0.0 6.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CBZ31065.1 - 8.4e-05 21.7 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 CBZ31065.1 - 0.00018 22.3 0.0 0.00038 21.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CBZ31065.1 - 0.00072 19.5 0.0 0.0018 18.2 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CBZ31065.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CBZ31065.1 - 0.0014 18.3 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 CBZ31065.1 - 0.0054 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CBZ31065.1 - 0.029 14.5 0.0 0.07 13.3 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CBZ31065.1 - 0.033 14.0 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CBZ31065.1 - 0.047 13.8 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SRPRB PF09439.5 CBZ31065.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CBZ31066.1 - 0.00074 19.4 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_C97 PF05903.9 CBZ31067.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain Pkinase PF00069.20 CBZ31068.1 - 3.8e-53 180.2 0.0 5.5e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ31068.1 - 2.6e-35 121.7 0.0 4.2e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ31068.1 - 6.2e-08 31.9 0.0 2.6e-07 29.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like PH PF00169.24 CBZ31068.1 - 3.9e-07 30.2 0.0 7.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Mcp5_PH PF12814.2 CBZ31068.1 - 0.00077 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology zf-CCCH PF00642.19 CBZ31069.1 - 7.3e-06 25.5 6.3 1.3e-05 24.7 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 CBZ31070.1 - 2.1e-12 47.0 0.0 2.4e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CBZ31070.1 - 7.3e-05 21.9 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CBZ31070.1 - 0.005 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 CBZ31070.1 - 0.011 15.5 0.9 2.3 8.0 0.0 2.9 2 1 1 3 3 3 0 Dynamin family FeoB_N PF02421.13 CBZ31070.1 - 0.024 13.9 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 CBZ31070.1 - 0.15 11.0 0.0 0.32 9.9 0.0 1.4 1 0 0 1 1 1 0 Septin Dyp_perox PF04261.7 CBZ31071.1 - 0.042 12.5 0.2 0.079 11.6 0.1 1.4 1 1 0 1 1 1 0 Dyp-type peroxidase family DivIVA PF05103.8 CBZ31071.1 - 0.87 9.6 0.1 0.87 9.6 0.0 3.5 2 1 1 4 4 4 0 DivIVA protein Syntaxin PF00804.20 CBZ31071.1 - 6.7 6.9 7.1 18 5.5 1.4 2.6 3 0 0 3 3 3 0 Syntaxin Methyltransf_4 PF02390.12 CBZ31072.1 - 1.4e-37 128.7 0.0 1.7e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CBZ31072.1 - 1.9e-05 25.2 0.0 3.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CBZ31072.1 - 9.3e-05 22.0 0.0 0.00026 20.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CBZ31072.1 - 0.0088 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 CBZ31072.1 - 0.099 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Glycos_transf_1 PF00534.15 CBZ31074.1 - 4.9e-20 71.6 0.0 6.9e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CBZ31074.1 - 1.5e-08 34.9 0.1 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CBZ31074.1 - 0.0016 18.6 0.0 0.0049 17.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 HALZ PF02183.13 CBZ31075.1 - 2.2e-06 27.2 0.9 2.2e-06 27.2 0.7 1.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper Rootletin PF15035.1 CBZ31075.1 - 0.0026 17.7 0.8 0.0028 17.6 0.5 1.1 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion DivIVA PF05103.8 CBZ31075.1 - 0.0052 16.8 0.4 0.0052 16.8 0.2 1.7 2 0 0 2 2 2 1 DivIVA protein Kinetocho_Slk19 PF12709.2 CBZ31075.1 - 0.0077 16.2 2.0 0.0089 16.0 1.4 1.2 1 0 0 1 1 1 1 Central kinetochore-associated Prp19 PF08606.6 CBZ31075.1 - 0.01 15.5 0.5 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Prp19/Pso4-like HalX PF08663.5 CBZ31075.1 - 0.013 15.5 0.5 0.025 14.5 0.1 1.6 2 0 0 2 2 2 0 HalX domain DivIC PF04977.10 CBZ31075.1 - 0.022 14.2 0.6 0.022 14.2 0.4 1.8 2 0 0 2 2 2 0 Septum formation initiator AvrPto PF11592.3 CBZ31075.1 - 0.022 14.5 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto Urb2 PF10441.4 CBZ31075.1 - 0.03 13.9 0.1 0.032 13.8 0.1 1.1 1 0 0 1 1 1 0 Urb2/Npa2 family DUF1640 PF07798.6 CBZ31075.1 - 0.033 14.2 0.1 0.038 14.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) K-box PF01486.12 CBZ31075.1 - 0.045 13.5 1.0 0.096 12.4 0.2 1.8 1 1 2 3 3 3 0 K-box region Dpy-30 PF05186.8 CBZ31075.1 - 0.049 13.1 0.2 0.13 11.7 0.2 1.7 1 1 0 1 1 1 0 Dpy-30 motif bZIP_1 PF00170.16 CBZ31075.1 - 0.068 13.1 0.2 0.068 13.1 0.1 1.7 2 1 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 CBZ31075.1 - 0.074 12.8 1.1 0.074 12.8 0.7 1.8 2 1 0 2 2 2 0 Basic region leucine zipper SinI PF08671.5 CBZ31075.1 - 0.1 12.0 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Anti-repressor SinI CCDC155 PF14662.1 CBZ31075.1 - 0.13 11.8 2.3 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 BMFP PF04380.8 CBZ31075.1 - 0.18 11.9 1.6 0.51 10.5 0.8 2.0 1 1 0 1 1 1 0 Membrane fusogenic activity DUF972 PF06156.8 CBZ31075.1 - 0.2 12.0 1.3 1.2 9.4 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) WD40 PF00400.27 CBZ31076.1 - 3.2e-16 58.4 10.4 6.6e-06 25.8 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat AD PF09793.4 CBZ31078.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain 7tm_6 PF02949.15 CBZ31079.1 - 0.071 11.9 0.9 0.12 11.2 0.6 1.2 1 0 0 1 1 1 0 7tm Odorant receptor TGS PF02824.16 CBZ31080.1 - 9e-23 79.8 0.0 1.9e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CBZ31080.1 - 4.4e-17 62.0 0.0 1.2e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CBZ31080.1 - 5.2e-10 38.8 0.0 9.8e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CBZ31080.1 - 0.0002 21.2 0.3 0.063 13.0 0.0 2.4 1 1 0 2 2 2 2 Dynamin family Miro PF08477.8 CBZ31080.1 - 0.00032 21.1 0.0 0.0011 19.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 CBZ31080.1 - 0.046 12.8 0.0 0.078 12.0 0.0 1.4 1 0 0 1 1 1 0 AIG1 family SAC3_GANP PF03399.11 CBZ31081.1 - 3.6e-30 105.0 0.1 5.1e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family FMN_dh PF01070.13 CBZ31082.1 - 1.2e-35 123.0 0.0 2.1e-22 79.4 0.0 2.0 1 1 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 CBZ31082.1 - 3.9e-07 29.2 0.8 0.0011 17.9 0.2 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 CBZ31082.1 - 2.7e-05 23.2 1.0 0.00016 20.6 0.7 2.0 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CBZ31082.1 - 0.0059 15.8 0.1 0.01 15.0 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 CBZ31082.1 - 0.35 10.1 2.1 1.4 8.1 0.1 2.4 2 1 1 3 3 3 0 Histidine biosynthesis protein Ank_2 PF12796.2 CBZ31083.1 - 2.8e-08 33.9 0.0 6.9e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CBZ31083.1 - 5e-08 32.3 0.0 9e-06 25.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 CBZ31083.1 - 1.3e-06 28.7 0.0 0.038 14.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Dynein_heavy PF03028.10 CBZ31083.1 - 3.7e-06 25.2 0.0 5.3e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor Ank_3 PF13606.1 CBZ31083.1 - 0.00063 19.7 0.0 0.19 12.0 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CBZ31083.1 - 0.076 13.2 0.0 1.7 9.0 0.0 2.8 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Aa_trans PF01490.13 CBZ31084.1 - 5.1e-57 193.1 32.4 5.8e-57 193.0 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.13 CBZ31085.1 - 5.7e-51 173.2 34.3 6.4e-51 173.1 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ31085.1 - 2.8e-06 26.4 20.6 8.9e-06 24.7 13.5 2.2 1 1 1 2 2 2 2 Tryptophan/tyrosine permease family DAGK_acc PF00609.14 CBZ31086.1 - 2.3e-37 128.6 0.0 3.2e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 CBZ31086.1 - 4.2e-13 48.8 0.0 6.9e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 CBZ31086.1 - 0.0074 15.0 0.0 0.014 14.2 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase HECT PF00632.20 CBZ31088.1 - 2.5e-40 138.5 0.1 4.9e-40 137.6 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 CBZ31088.1 - 2.8e-12 46.8 2.1 2.8e-05 24.1 0.0 4.8 5 0 0 5 5 5 3 SPRY domain DUF3895 PF13034.1 CBZ31088.1 - 0.54 9.7 0.5 3.2 7.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3895) YL1 PF05764.8 CBZ31088.1 - 3 7.4 0.7 4.6 6.7 0.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Amastin PF07344.6 CBZ40909.1 - 2.6e-33 114.8 12.4 3e-33 114.6 8.6 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ40909.1 - 0.00015 21.4 11.6 0.0002 21.1 8.1 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Ceramidase PF05875.7 CBZ40909.1 - 0.096 11.8 2.3 0.11 11.6 1.6 1.0 1 0 0 1 1 1 0 Ceramidase DUF805 PF05656.9 CBZ40909.1 - 0.29 10.9 8.0 0.49 10.2 5.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) MIG-14_Wnt-bd PF06664.7 CBZ40909.1 - 0.39 9.4 5.3 0.99 8.1 3.7 1.7 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion CDP-OH_P_transf PF01066.16 CBZ40909.1 - 2.6 8.3 7.8 0.75 10.1 0.2 2.2 1 1 1 2 2 2 0 CDP-alcohol phosphatidyltransferase DUF2417 PF10329.4 CBZ40909.1 - 3.3 7.0 8.5 1.8 7.8 0.0 2.1 1 1 1 2 2 2 0 Region of unknown function (DUF2417) DUF2976 PF11190.3 CBZ40909.1 - 9.4 5.8 7.7 1.5 8.3 1.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2976) Inhibitor_I29 PF08246.7 CBZ40910.1 - 7.9e-12 45.2 0.6 9.1e-12 45.0 0.4 1.1 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) IncA PF04156.9 CBZ40910.1 - 0.079 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 IncA protein Peptidase_S64 PF08192.6 CBZ40910.1 - 0.097 10.9 0.0 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_C1 PF00112.18 CBZ40911.1 - 8.6e-72 241.5 0.9 1.1e-71 241.1 0.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBZ40911.1 - 5e-12 45.8 1.0 7.9e-12 45.2 0.7 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBZ40911.1 - 1.2e-06 27.3 0.2 4.3e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Amastin PF07344.6 CBZ40912.1 - 2.9e-46 156.8 8.5 3.5e-46 156.6 5.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 CBZ40912.1 - 0.032 13.8 4.7 0.042 13.5 3.2 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Reticulon PF02453.12 CBZ40912.1 - 5 6.7 12.1 7 6.2 2.6 2.4 1 1 1 2 2 2 0 Reticulon DUF2721 PF11026.3 CBZ40912.1 - 5.2 6.7 9.9 29 4.2 5.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF1218 PF06749.7 CBZ40912.1 - 7.7 7.0 12.6 0.71 10.3 1.9 3.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1218) TrbC PF04956.8 CBZ40912.1 - 8.3 6.4 10.4 0.51 10.3 0.1 2.6 2 1 1 3 3 3 0 TrbC/VIRB2 family Amastin PF07344.6 CBZ40913.1 - 4.6e-53 178.9 10.9 5.9e-53 178.6 7.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4293 PF14126.1 CBZ40913.1 - 2 8.3 8.9 16 5.4 6.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Claudin_2 PF13903.1 CBZ40913.1 - 7.5 6.2 16.2 1.4 8.5 6.7 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MFS_1 PF07690.11 CBZ40914.1 - 2.6e-13 49.4 26.7 6.7e-12 44.7 11.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 CBZ40914.1 - 3e-07 29.9 13.1 3e-07 29.9 9.1 2.7 2 2 0 2 2 2 1 Nodulin-like Ribosomal_L28e PF01778.12 CBZ40916.1 - 8.1e-20 71.3 0.5 1.5e-19 70.5 0.1 1.5 1 1 0 1 1 1 1 Ribosomal L28e protein family bPH_6 PF10756.4 CBZ40916.1 - 0.025 14.4 0.9 0.039 13.8 0.7 1.4 1 0 0 1 1 1 0 Bacterial PH domain Corona_I PF03187.9 CBZ40917.1 - 1.1e-05 24.6 2.8 6.2 5.9 0.0 4.4 4 0 0 4 4 4 4 Corona nucleocapsid I protein B12-binding PF02310.14 CBZ40917.1 - 0.002 17.9 0.3 36 4.2 0.0 4.0 4 0 0 4 4 4 2 B12 binding domain PSD2 PF07624.6 CBZ40917.1 - 0.014 15.0 0.4 1.3e+02 2.2 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1585) Joubert PF15392.1 CBZ40919.1 - 0.056 12.6 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated LRR_4 PF12799.2 CBZ40922.1 - 2.8e-06 26.8 0.0 0.072 12.7 0.0 3.2 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ40922.1 - 3.1e-06 26.8 0.1 0.01 15.5 0.0 2.6 2 1 0 2 2 2 2 Leucine rich repeat AAA_14 PF13173.1 CBZ40923.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CBZ40923.1 - 0.023 14.6 0.1 0.04 13.9 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Peptidase_C2 PF00648.16 CBZ40924.1 - 4.1e-53 180.3 0.0 5.3e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Glyco_hydro_32N PF00251.15 CBZ40925.1 - 7.6e-84 281.6 0.2 1.2e-83 281.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CBZ40925.1 - 2e-08 34.4 0.0 3.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.9 CBZ40925.1 - 6.4e-07 28.7 0.4 1e-06 28.0 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 CBZ40926.1 - 5.3e-80 269.0 0.1 8.1e-80 268.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 CBZ40926.1 - 1.9e-08 34.5 0.0 3.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.9 CBZ40926.1 - 6.2e-07 28.7 0.5 9.3e-07 28.2 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Amastin PF07344.6 CBZ40927.1 - 8.7e-52 174.8 6.6 1e-51 174.5 4.6 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein CD20 PF04103.10 CBZ40927.1 - 0.00022 21.1 0.0 0.017 15.0 0.0 2.3 1 1 1 2 2 2 1 CD20-like family DUF975 PF06161.6 CBZ40927.1 - 0.016 14.9 0.4 0.016 14.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF975) DUF4199 PF13858.1 CBZ40927.1 - 0.28 11.0 8.3 0.069 13.0 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) UNC-50 PF05216.8 CBZ40927.1 - 1.3 8.1 8.9 0.047 12.8 1.7 1.7 2 0 0 2 2 2 0 UNC-50 family Claudin_2 PF13903.1 CBZ40927.1 - 1.7 8.3 15.8 0.12 12.0 6.5 2.1 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBZ40928.1 - 1.4e-46 157.9 10.6 1.6e-46 157.7 7.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ40928.1 - 2.5e-05 24.0 8.3 2.5e-05 24.0 5.8 1.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2417 PF10329.4 CBZ40928.1 - 8.6 5.6 8.3 4 6.7 0.1 2.3 1 1 0 2 2 2 0 Region of unknown function (DUF2417) Amastin PF07344.6 CBZ40930.1 - 1.9e-49 167.2 13.4 2.3e-49 166.9 9.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein TM140 PF14985.1 CBZ40930.1 - 1.7 8.2 9.3 0.82 9.3 4.9 1.7 1 1 0 1 1 1 0 TM140 protein family Claudin_2 PF13903.1 CBZ40930.1 - 4.1 7.0 20.1 0.04 13.5 8.3 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction CbiQ PF02361.11 CBZ40930.1 - 9.3 5.7 13.7 1.7 8.1 4.8 1.9 1 1 1 2 2 2 0 Cobalt transport protein Aa_trans PF01490.13 CBZ40932.1 - 1.7e-59 201.3 25.5 2.1e-59 201.0 17.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ40932.1 - 1.1e-10 40.9 7.0 2.4e-10 39.7 4.9 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DAGAT PF03982.8 CBZ40933.1 - 7.7e-22 77.3 0.1 1.4e-21 76.4 0.0 1.4 2 0 0 2 2 2 1 Diacylglycerol acyltransferase Acyltransferase PF01553.16 CBZ40933.1 - 0.037 13.4 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Acyltransferase MitoNEET_N PF10660.4 CBZ40933.1 - 0.06 13.2 0.4 0.19 11.5 0.1 1.9 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Amastin PF07344.6 CBZ40934.1 - 1.1e-22 80.2 9.0 1.3e-22 80.0 6.2 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein CD20 PF04103.10 CBZ40934.1 - 0.011 15.6 0.1 0.026 14.4 0.0 1.8 1 1 0 1 1 1 0 CD20-like family UPF0233 PF06781.7 CBZ40934.1 - 0.97 9.1 7.3 0.076 12.6 1.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) Claudin_2 PF13903.1 CBZ40934.1 - 1.5 8.5 8.1 2.2 7.9 5.6 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1469 PF07332.6 CBZ40934.1 - 8.7 6.1 11.3 1 9.0 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) Amastin PF07344.6 CBZ40935.1 - 4.6e-50 169.2 9.4 5.6e-50 168.9 6.5 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ40935.1 - 0.0034 17.0 8.2 0.0034 17.0 5.7 2.2 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF4525 PF15027.1 CBZ40935.1 - 0.83 9.1 2.9 8.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DUF1935 PF09149.5 CBZ40936.1 - 5.7e-20 71.2 0.0 1.8e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) Joubert PF15392.1 CBZ40938.1 - 0.00015 21.1 0.2 0.52 9.4 0.0 2.2 2 0 0 2 2 2 2 Joubert syndrome-associated Corona_I PF03187.9 CBZ40938.1 - 0.0066 15.6 3.8 29 3.7 0.0 4.1 4 0 0 4 4 4 3 Corona nucleocapsid I protein HK97-gp10_like PF04883.7 CBZ40938.1 - 0.51 11.3 0.4 68 4.4 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component LRR_4 PF12799.2 CBZ40939.1 - 6.5e-08 32.0 0.1 0.073 12.7 0.1 3.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ40939.1 - 0.00042 20.0 0.0 0.09 12.5 0.0 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRRNT_2 PF08263.7 CBZ40939.1 - 0.012 15.5 0.5 0.068 13.1 0.3 2.4 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Cornifin PF02389.10 CBZ40939.1 - 0.016 15.0 32.2 0.025 14.3 22.3 1.2 1 0 0 1 1 1 0 Cornifin (SPRR) family TFIIA PF03153.8 CBZ40939.1 - 0.73 9.6 11.9 1 9.1 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C2 PF00648.16 CBZ40940.1 - 6.4e-45 153.4 0.0 9.4e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ40940.1 - 3.2e-20 72.0 0.0 9.6e-20 70.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.16 CBZ40941.1 - 1.5e-31 109.5 0.0 2.2e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ40941.1 - 1.1e-24 86.3 0.0 2.2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DivIC PF04977.10 CBZ40941.1 - 0.28 10.6 0.3 0.51 9.8 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator Peptidase_C2 PF00648.16 CBZ40942.1 - 2.1e-56 191.1 0.0 2.8e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ40942.1 - 1.3e-21 76.4 0.3 2.5e-21 75.6 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) LRR_4 PF12799.2 CBZ40944.1 - 2.4e-18 65.2 12.3 2.1e-05 23.9 0.0 6.4 5 1 1 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CBZ40944.1 - 2.8e-13 47.8 6.6 0.25 11.5 0.1 10.1 10 0 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.1 CBZ40944.1 - 6.5e-13 48.2 9.3 1.5e-06 27.8 0.3 4.3 2 2 3 5 5 5 5 Leucine rich repeat DUF605 PF04652.11 CBZ40944.1 - 0.00013 21.4 40.3 0.00018 21.0 27.9 1.2 1 0 0 1 1 1 1 Vta1 like DUF3338 PF11819.3 CBZ40944.1 - 0.084 12.3 0.0 43 3.5 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3338) LRR_7 PF13504.1 CBZ40944.1 - 5 7.7 13.6 16 6.2 0.9 5.7 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 CBZ40944.1 - 7.5 6.9 16.0 4.3 7.7 0.2 5.7 7 1 1 8 8 8 0 Leucine Rich repeat FA_desaturase PF00487.19 CBZ40947.1 - 4e-25 88.7 25.4 5.9e-25 88.1 17.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 CBZ40947.1 - 0.00073 18.7 0.1 0.0013 17.9 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) GPI2 PF06432.6 CBZ40947.1 - 8.9 5.5 11.3 0.6 9.3 4.2 1.6 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase ABC_tran PF00005.22 CBZ40948.1 - 1.7e-25 89.8 0.0 5.2e-25 88.3 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 CBZ40948.1 - 1.6e-09 38.1 0.2 1.2e-06 28.7 0.0 2.4 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 CBZ40948.1 - 0.026 13.6 0.8 4.8 6.2 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_23 PF13476.1 CBZ40948.1 - 0.027 14.8 1.9 0.25 11.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 CBZ40948.1 - 0.036 13.5 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.24 CBZ40948.1 - 0.07 13.3 0.7 0.24 11.5 0.1 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 CBZ40948.1 - 0.13 11.3 0.0 5.1 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain LRR_8 PF13855.1 CBZ40949.1 - 3.9e-12 45.7 4.1 0.0025 17.5 0.2 3.6 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 CBZ40949.1 - 1.9e-11 43.2 4.3 1.5e-05 24.4 1.3 5.2 2 2 4 7 7 7 5 Leucine Rich repeats (2 copies) Amastin PF07344.6 CBZ40950.1 - 3e-52 176.3 7.6 3.6e-52 176.0 5.2 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein CD20 PF04103.10 CBZ40950.1 - 0.00046 20.1 0.0 0.015 15.2 0.0 2.4 1 1 1 2 2 2 1 CD20-like family DUF4525 PF15027.1 CBZ40950.1 - 0.51 9.8 2.6 7.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) DUF975 PF06161.6 CBZ40950.1 - 0.64 9.7 5.3 0.092 12.4 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF975) Claudin_2 PF13903.1 CBZ40950.1 - 0.67 9.6 17.1 0.04 13.6 7.0 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Baculo_11_kDa PF06143.6 CBZ40950.1 - 4.6 6.6 0.0 4.6 6.6 0.0 2.9 2 1 1 3 3 3 0 Baculovirus 11 kDa family Peptidase_C1 PF00112.18 CBZ40951.1 - 3.3e-71 239.6 0.8 4.2e-71 239.3 0.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBZ40951.1 - 4.5e-12 46.0 1.0 7e-12 45.4 0.7 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBZ40951.1 - 9.1e-06 24.4 0.6 0.00071 18.2 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C1 PF00112.18 CBZ40952.1 - 1.2e-32 113.5 0.1 1.2e-32 113.5 0.1 1.9 2 0 0 2 2 2 1 Papain family cysteine protease DUF3586 PF12131.3 CBZ40952.1 - 6.5e-28 96.5 6.8 1.7e-27 95.2 4.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Peptidase_C1_2 PF03051.10 CBZ40952.1 - 0.00014 20.5 0.0 0.00017 20.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C1-like family Amastin PF07344.6 CBZ40953.1 - 6.2e-20 71.3 0.1 7.2e-20 71.1 0.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein 7TM-7TMR_HD PF07698.6 CBZ40953.1 - 0.24 10.8 2.9 0.53 9.6 2.0 1.7 1 1 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Amastin PF07344.6 CBZ40954.1 - 3.4e-38 130.7 4.1 3.8e-38 130.5 2.8 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Ribosomal_S3Ae PF01015.13 CBZ40955.1 - 1.5e-61 207.1 4.6 1.7e-61 206.9 3.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family TMEM156 PF15106.1 CBZ40955.1 - 0.032 13.4 0.1 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 TMEM156 protein family DNA_pol3_delt_C PF14840.1 CBZ40955.1 - 0.068 13.2 2.4 0.11 12.6 1.4 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Ribosomal_S3Ae PF01015.13 CBZ40956.1 - 1.5e-61 207.1 4.6 1.7e-61 206.9 3.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family TMEM156 PF15106.1 CBZ40956.1 - 0.032 13.4 0.1 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 TMEM156 protein family DNA_pol3_delt_C PF14840.1 CBZ40956.1 - 0.068 13.2 2.4 0.11 12.6 1.4 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term MFS_1 PF07690.11 CBZ40957.1 - 3.7e-25 88.3 27.0 3.2e-19 68.8 11.7 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CBZ40957.1 - 9.3e-07 27.7 23.6 1.2e-05 24.0 6.6 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 CBZ40957.1 - 0.0078 15.9 1.0 0.039 13.7 0.0 2.7 3 0 0 3 3 3 1 MFS_1 like family Amastin PF07344.6 CBZ40958.1 - 3.6e-50 169.5 9.4 4.3e-50 169.3 6.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ40958.1 - 3.1e-06 27.0 7.0 3.1e-06 27.0 4.9 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBZ40960.1 - 1.1e-53 180.9 10.4 1.4e-53 180.7 7.2 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ40960.1 - 1.6e-05 24.6 11.1 1.6e-05 24.6 7.7 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CBZ40960.1 - 0.0082 15.8 8.0 0.011 15.3 5.6 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family COX3 PF00510.13 CBZ40960.1 - 0.0086 15.5 1.4 0.017 14.6 0.9 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III DUF1467 PF07330.7 CBZ40960.1 - 2.5 7.9 0.0 2.5 7.9 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1467) DUF4293 PF14126.1 CBZ40960.1 - 9.8 6.0 10.9 39 4.1 7.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) Amastin PF07344.6 CBZ40962.1 - 1.4e-46 157.9 10.6 1.6e-46 157.7 7.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ40962.1 - 2.5e-05 24.0 8.3 2.5e-05 24.0 5.8 1.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2417 PF10329.4 CBZ40962.1 - 8.6 5.6 8.3 4 6.7 0.1 2.3 1 1 0 2 2 2 0 Region of unknown function (DUF2417) Nop52 PF05997.7 CBZ40963.1 - 0.019 14.3 0.0 0.038 13.4 0.0 1.5 1 1 0 1 1 1 0 Nucleolar protein,Nop52 PDDEXK_1 PF12705.2 CBZ40963.1 - 0.068 12.5 1.4 0.086 12.2 1.0 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF3184 PF11380.3 CBZ40964.1 - 0 1068.5 33.7 5.8e-207 688.9 12.0 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3184) DUF1275 PF06912.6 CBZ40964.1 - 0.11 11.6 0.2 0.22 10.7 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Peptidase_C1 PF00112.18 CBZ40965.1 - 3.3e-34 118.6 0.4 4.5e-34 118.2 0.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 CBZ40965.1 - 2.5e-12 46.8 1.0 3.8e-12 46.2 0.7 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1 PF00112.18 CBZ40966.1 - 2e-71 240.3 0.7 2e-71 240.3 0.5 1.9 2 0 0 2 2 2 1 Papain family cysteine protease DUF3586 PF12131.3 CBZ40966.1 - 2e-26 91.8 8.4 2e-26 91.8 5.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.7 CBZ40966.1 - 8e-12 45.2 1.0 1.3e-11 44.5 0.7 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBZ40966.1 - 1.1e-05 24.2 0.2 0.00059 18.4 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family MBOAT PF03062.14 CBZ40967.1 - 7.9e-30 104.0 18.8 1.3e-29 103.3 13.0 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PUF PF00806.14 CBZ40968.1 - 3.1e-18 64.1 0.0 0.002 17.5 0.0 4.5 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat PUF PF00806.14 CBZ40969.1 - 1.1e-07 30.8 0.0 0.0023 17.3 0.0 2.6 2 0 0 2 2 2 2 Pumilio-family RNA binding repeat DnaB_bind PF10410.4 CBZ40969.1 - 0.15 12.0 0.1 0.57 10.2 0.1 2.0 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase TCTP PF00838.12 CBZ40970.1 - 3.5e-37 127.9 0.4 4e-37 127.7 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Ribosomal_S20p PF01649.13 CBZ40970.1 - 0.012 15.9 0.7 0.02 15.2 0.5 1.3 1 0 0 1 1 1 0 Ribosomal protein S20 Trypan_glycop PF00913.14 CBZ40970.1 - 0.039 12.8 0.0 0.048 12.5 0.0 1.0 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) RICH PF05062.7 CBZ40970.1 - 0.046 13.8 0.4 0.079 13.0 0.3 1.3 1 0 0 1 1 1 0 RICH domain AAA_15 PF13175.1 CBZ40970.1 - 0.052 12.5 0.6 0.058 12.4 0.4 1.0 1 0 0 1 1 1 0 AAA ATPase domain AlaDh_PNT_C PF01262.16 CBZ40970.1 - 0.088 12.3 0.5 0.12 11.9 0.3 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Cauli_DNA-bind PF03310.8 CBZ40970.1 - 0.11 12.3 0.1 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Peripla_BP_6 PF13458.1 CBZ40971.1 - 1.7e-10 40.7 0.4 1.1e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding protein Ribosomal_L10 PF00466.15 CBZ40973.1 - 7.5e-24 83.5 0.2 1.6e-23 82.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CBZ40973.1 - 6e-14 52.2 4.8 6e-14 52.2 3.3 2.5 4 0 0 4 4 4 1 60s Acidic ribosomal protein Ribosomal_60s PF00428.14 CBZ40974.1 - 1.7e-14 53.9 6.4 2.2e-14 53.5 3.3 1.9 2 0 0 2 2 2 1 60s Acidic ribosomal protein Pkinase PF00069.20 CBZ40975.1 - 3e-50 170.7 0.0 3.7e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ40975.1 - 1.3e-16 60.4 0.0 1.8e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CBZ40975.1 - 0.011 15.5 0.3 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CBZ40975.1 - 0.054 12.5 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Laminin_I PF06008.9 CBZ40976.1 - 2.3e-25 89.4 161.3 0.0002 20.7 12.6 9.7 1 1 9 10 10 10 10 Laminin Domain I Spc7 PF08317.6 CBZ40976.1 - 8.7e-13 47.6 149.7 0.043 12.4 2.5 6.3 1 1 5 6 6 6 6 Spc7 kinetochore protein DUF3552 PF12072.3 CBZ40976.1 - 6.2e-12 45.1 165.4 0.19 10.9 10.5 10.9 1 1 9 10 10 10 6 Domain of unknown function (DUF3552) Laminin_II PF06009.7 CBZ40976.1 - 7.1e-12 45.2 137.2 0.35 10.6 7.9 10.7 1 1 7 9 9 9 7 Laminin Domain II TMF_DNA_bd PF12329.3 CBZ40976.1 - 2.8e-10 39.8 213.1 0.0041 16.8 10.4 12.4 2 1 11 13 13 13 12 TATA element modulatory factor 1 DNA binding Tropomyosin PF00261.15 CBZ40976.1 - 1.4e-09 37.3 190.3 0.0015 17.6 37.4 5.3 1 1 5 6 6 6 4 Tropomyosin IFT57 PF10498.4 CBZ40976.1 - 5.4e-09 35.2 130.6 0.078 11.7 10.2 8.7 1 1 8 9 9 9 8 Intra-flagellar transport protein 57 COG2 PF06148.6 CBZ40976.1 - 5.8e-09 35.9 106.5 1.6 8.5 3.0 12.2 1 1 13 15 15 15 13 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 CBZ40976.1 - 7e-09 35.3 111.1 0.42 9.7 11.5 8.0 1 1 6 8 8 8 8 Reovirus sigma C capsid protein DUF4200 PF13863.1 CBZ40976.1 - 9.5e-09 35.2 154.1 0.43 10.5 13.5 11.2 1 1 9 10 10 10 5 Domain of unknown function (DUF4200) V-SNARE_C PF12352.3 CBZ40976.1 - 8.7e-08 32.1 78.2 1.9 8.5 2.1 12.1 2 1 12 15 15 15 11 Snare region anchored in the vesicle membrane C-terminus IncA PF04156.9 CBZ40976.1 - 1.5e-07 31.2 185.5 0.5 9.9 20.3 6.4 1 1 5 6 6 6 4 IncA protein Atg14 PF10186.4 CBZ40976.1 - 0.00028 19.9 132.2 0.16 10.9 15.2 6.2 1 1 6 7 7 7 4 UV radiation resistance protein and autophagy-related subunit 14 APG17 PF04108.7 CBZ40976.1 - 0.0015 17.3 19.7 0.0015 17.3 13.6 6.9 1 1 5 6 6 4 1 Autophagy protein Apg17 ATG16 PF08614.6 CBZ40976.1 - 0.0071 16.1 169.3 0.36 10.6 0.8 7.3 1 1 6 7 7 5 1 Autophagy protein 16 (ATG16) Filament PF00038.16 CBZ40976.1 - 0.0082 15.6 7.9 0.0082 15.6 5.5 8.6 1 1 8 9 9 8 1 Intermediate filament protein Tropomyosin_1 PF12718.2 CBZ40976.1 - 0.035 13.9 224.3 8.9 6.1 26.4 7.5 1 1 6 7 7 7 0 Tropomyosin like MCPsignal PF00015.16 CBZ40976.1 - 0.38 10.2 126.3 3.4 7.1 11.0 7.4 1 1 5 6 6 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FliJ PF02050.11 CBZ40976.1 - 1.1 9.2 128.3 3.7 7.6 5.8 8.6 1 1 5 8 8 8 0 Flagellar FliJ protein Snapin_Pallidin PF14712.1 CBZ40976.1 - 1.3 9.3 110.6 1.1 9.6 7.2 9.7 2 2 5 9 9 9 0 Snapin/Pallidin EzrA PF06160.7 CBZ40976.1 - 1.7 6.6 132.2 18 3.3 22.5 3.9 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA TMPIT PF07851.8 CBZ40976.1 - 1.8 7.5 102.6 4.5 6.2 7.7 7.5 1 1 8 9 9 9 0 TMPIT-like protein Vps5 PF09325.5 CBZ40976.1 - 2.6 7.2 134.0 6.3 5.9 11.3 8.1 1 1 5 7 7 7 0 Vps5 C terminal like MscS_porin PF12795.2 CBZ40976.1 - 7.4 5.8 211.4 5.5 6.2 13.9 8.6 1 1 7 8 8 7 0 Mechanosensitive ion channel porin domain Amastin PF07344.6 CBZ40977.1 - 1.4e-46 157.9 10.6 1.6e-46 157.7 7.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ40977.1 - 2.5e-05 24.0 8.3 2.5e-05 24.0 5.8 1.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2417 PF10329.4 CBZ40977.1 - 8.6 5.6 8.3 4 6.7 0.1 2.3 1 1 0 2 2 2 0 Region of unknown function (DUF2417) Cast PF10174.4 CBZ40978.1 - 3.5e-28 98.1 177.2 1.7e-17 62.8 86.5 4.2 1 1 1 3 3 3 3 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 CBZ40978.1 - 7.6e-16 58.2 189.8 0.015 14.9 17.2 8.1 1 1 14 15 15 15 15 IncA protein CENP-F_leu_zip PF10473.4 CBZ40978.1 - 8.9e-16 58.0 201.0 0.19 11.6 9.3 10.7 1 1 11 12 12 12 12 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2051 PF09738.4 CBZ40978.1 - 1e-12 47.9 133.3 0.045 13.0 2.8 12.5 1 1 19 20 20 20 19 Double stranded RNA binding protein (DUF2051) TPR_MLP1_2 PF07926.7 CBZ40978.1 - 4.4e-11 42.6 185.4 0.0011 18.7 15.7 9.3 1 1 8 9 9 9 6 TPR/MLP1/MLP2-like protein MscS_porin PF12795.2 CBZ40978.1 - 1.4e-10 40.9 179.7 0.0023 17.3 24.6 6.9 1 1 4 6 6 6 6 Mechanosensitive ion channel porin domain COG5 PF10392.4 CBZ40978.1 - 1.8e-09 37.6 48.0 2.1 8.3 0.2 13.7 1 1 18 19 19 19 7 Golgi transport complex subunit 5 L27_2 PF09045.5 CBZ40978.1 - 5.2e-08 32.3 125.1 9.1 5.9 0.2 22.3 13 3 7 21 21 21 0 L27_2 APG6 PF04111.7 CBZ40978.1 - 1.7e-07 30.6 180.5 0.0068 15.4 15.7 7.6 1 1 9 10 10 10 9 Autophagy protein Apg6 THOC7 PF05615.8 CBZ40978.1 - 6.8e-07 29.6 166.2 1.4 9.1 3.6 17.7 1 1 20 21 21 21 10 Tho complex subunit 7 Atg14 PF10186.4 CBZ40978.1 - 7.9e-07 28.3 145.8 0.59 9.0 6.5 9.6 1 1 12 13 13 13 8 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 CBZ40978.1 - 9.6e-07 28.5 159.5 0.4 10.1 11.5 10.1 1 1 11 12 12 12 5 Intermediate filament protein Myosin_tail_1 PF01576.14 CBZ40978.1 - 4.3e-06 24.7 204.7 0.0042 14.8 61.8 3.6 1 1 2 3 3 3 3 Myosin tail Rootletin PF15035.1 CBZ40978.1 - 7.6e-06 26.0 184.2 2.7 7.9 2.2 20.2 1 1 20 21 21 21 10 Ciliary rootlet component, centrosome cohesion DUF4201 PF13870.1 CBZ40978.1 - 0.00033 20.1 129.5 0.85 9.0 6.6 10.7 1 1 11 12 12 12 3 Domain of unknown function (DUF4201) HrpB7 PF09486.5 CBZ40978.1 - 0.00092 19.1 197.4 0.55 10.1 2.0 20.3 1 1 20 21 21 21 9 Bacterial type III secretion protein (HrpB7) HOOK PF05622.7 CBZ40978.1 - 0.0042 14.9 169.3 0.34 8.6 22.8 5.8 1 1 4 5 5 5 5 HOOK protein AAA_13 PF13166.1 CBZ40978.1 - 0.015 13.8 119.9 0.22 9.9 14.9 4.7 1 1 2 4 4 4 0 AAA domain NTS PF15447.1 CBZ40978.1 - 0.031 14.6 136.2 19 5.7 0.2 22.0 22 0 0 22 22 22 0 N-terminal segments of PfEMP1 Kinetocho_Slk19 PF12709.2 CBZ40978.1 - 0.09 12.8 153.9 1.1 9.3 1.6 20.5 1 1 20 21 21 21 0 Central kinetochore-associated HAUS6_N PF14661.1 CBZ40978.1 - 0.13 11.6 150.0 3.8 6.7 5.9 10.3 1 1 13 14 14 14 0 HAUS augmin-like complex subunit 6 N-terminus Lebercilin PF15619.1 CBZ40978.1 - 0.13 11.6 171.7 0.33 10.3 15.0 8.1 1 1 8 10 10 10 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.1 CBZ40978.1 - 0.35 10.0 152.4 1.6 7.8 10.6 9.2 1 1 8 10 10 10 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.6 CBZ40978.1 - 1.8 6.7 157.8 0.15 10.3 25.9 4.9 1 1 3 5 5 5 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.1 CBZ40978.1 - 2.4 7.0 180.1 5.2 5.9 14.6 8.3 1 1 8 9 9 7 0 Domain of unknown function (DUF4407) WEMBL PF05701.6 CBZ40978.1 - 9.6 4.5 206.7 1.3 7.4 37.7 5.1 1 1 2 3 3 3 0 Weak chloroplast movement under blue light Kinesin PF00225.18 CBZ40981.1 - 6.1e-80 268.4 0.0 8.7e-79 264.6 0.0 3.2 1 0 0 1 1 1 1 Kinesin motor domain Laminin_I PF06008.9 CBZ40981.1 - 6.8e-48 163.2 366.3 4.8e-05 22.8 38.7 19.8 1 1 20 23 23 22 21 Laminin Domain I Spc7 PF08317.6 CBZ40981.1 - 1.8e-21 76.1 337.6 0.036 12.7 16.9 14.0 1 1 13 14 14 14 13 Spc7 kinetochore protein Laminin_II PF06009.7 CBZ40981.1 - 7.3e-19 67.8 308.4 0.094 12.4 8.1 22.4 2 1 25 27 27 27 22 Laminin Domain II DUF3552 PF12072.3 CBZ40981.1 - 9.3e-17 60.8 365.6 0.98 8.5 9.1 23.4 1 1 26 27 27 25 14 Domain of unknown function (DUF3552) Tropomyosin PF00261.15 CBZ40981.1 - 6.2e-14 51.6 424.5 0.0013 17.8 34.0 10.7 1 1 10 12 12 11 10 Tropomyosin Reo_sigmaC PF04582.7 CBZ40981.1 - 1.3e-12 47.5 245.6 0.79 8.8 6.3 16.5 2 1 14 17 17 17 14 Reovirus sigma C capsid protein COG2 PF06148.6 CBZ40981.1 - 2.2e-12 46.9 228.6 3.1 7.6 3.1 25.2 1 1 28 29 29 29 17 COG (conserved oligomeric Golgi) complex component, COG2 V-SNARE_C PF12352.3 CBZ40981.1 - 8.2e-11 41.8 176.8 2.2 8.4 0.4 24.6 2 1 19 25 25 24 11 Snare region anchored in the vesicle membrane C-terminus DUF4200 PF13863.1 CBZ40981.1 - 6.5e-09 35.8 349.9 0.22 11.4 13.4 22.6 2 1 20 22 22 20 8 Domain of unknown function (DUF4200) IFT57 PF10498.4 CBZ40981.1 - 2.8e-08 32.9 298.1 0.59 8.8 12.4 17.3 1 1 19 20 20 20 16 Intra-flagellar transport protein 57 IncA PF04156.9 CBZ40981.1 - 3.5e-06 26.7 413.2 1.6 8.3 20.0 14.4 1 1 10 12 12 10 2 IncA protein TMF_DNA_bd PF12329.3 CBZ40981.1 - 9.9e-06 25.2 476.9 0.0048 16.6 10.6 25.9 4 1 27 31 31 31 22 TATA element modulatory factor 1 DNA binding APG17 PF04108.7 CBZ40981.1 - 0.0021 16.9 24.5 0.0021 16.9 17.0 14.6 1 1 8 9 9 7 2 Autophagy protein Apg17 Atg14 PF10186.4 CBZ40981.1 - 0.044 12.7 288.0 3.2 6.5 13.7 13.3 1 1 13 14 14 14 0 UV radiation resistance protein and autophagy-related subunit 14 PRP38_assoc PF12871.2 CBZ40981.1 - 0.11 13.0 4.1 1.1e+02 3.3 2.8 6.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Amastin PF07344.6 CBZ40982.1 - 1.7e-49 167.4 8.5 2e-49 167.1 5.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein CD20 PF04103.10 CBZ40982.1 - 0.00081 19.3 0.1 0.85 9.5 0.0 2.4 1 1 1 2 2 2 2 CD20-like family Claudin_2 PF13903.1 CBZ40982.1 - 0.0012 18.5 6.4 0.0012 18.5 4.4 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF975 PF06161.6 CBZ40982.1 - 0.05 13.3 0.3 0.05 13.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF975) DUF4525 PF15027.1 CBZ40982.1 - 0.21 11.0 0.7 0.68 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) Peptidase_C2 PF00648.16 CBZ40983.1 - 1.3e-12 47.3 1.0 1.8e-12 46.8 0.7 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 CBZ40983.1 - 0.0044 16.6 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Calpain large subunit, domain III Amastin PF07344.6 CBZ40984.1 - 5.6e-56 188.4 7.7 6.7e-56 188.1 5.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ40984.1 - 0.0016 18.1 9.3 0.0016 18.1 6.5 2.0 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF3068 PF11271.3 CBZ40984.1 - 0.083 11.9 0.6 0.13 11.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) DUF4293 PF14126.1 CBZ40984.1 - 0.28 11.0 5.5 0.34 10.8 1.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF1218 PF06749.7 CBZ40984.1 - 1.7 9.1 13.7 0.25 11.7 1.3 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1218) Peptidase_M8 PF01457.11 CBZ40986.1 - 1.5e-133 445.8 0.3 1.8e-133 445.6 0.2 1.0 1 0 0 1 1 1 1 Leishmanolysin DUF1025 PF06262.6 CBZ40986.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 Possibl zinc metallo-peptidase Inhibitor_I29 PF08246.7 CBZ40987.1 - 1.3e-10 41.3 0.3 1.5e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) IncA PF04156.9 CBZ40987.1 - 0.059 12.9 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 IncA protein Peptidase_S64 PF08192.6 CBZ40987.1 - 0.072 11.4 0.0 0.082 11.2 0.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_C1 PF00112.18 CBZ40988.1 - 1.2e-71 241.1 0.7 1.2e-71 241.1 0.5 1.9 2 0 0 2 2 2 1 Papain family cysteine protease DUF3586 PF12131.3 CBZ40988.1 - 2.2e-26 91.7 8.4 2.2e-26 91.7 5.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3586) Inhibitor_I29 PF08246.7 CBZ40988.1 - 8.7e-12 45.1 1.0 1.4e-11 44.4 0.7 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 CBZ40988.1 - 1.2e-05 23.9 0.2 0.00064 18.3 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Brix PF04427.13 CBZ40989.1 - 5.6e-37 127.2 0.0 1.8e-36 125.5 0.0 1.7 2 0 0 2 2 2 1 Brix domain Spc7 PF08317.6 CBZ40989.1 - 0.072 11.7 0.2 5.5 5.5 0.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Mito_carr PF00153.22 CBZ40990.1 - 1.2e-54 181.9 0.3 1.8e-20 72.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Amastin PF07344.6 CBZ40992.1 - 6.8e-49 165.4 11.4 8.1e-49 165.1 7.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2427 PF10348.4 CBZ40992.1 - 0.0046 16.5 5.9 0.049 13.1 0.9 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF2427) Amastin PF07344.6 CBZ40994.1 - 1.2e-55 187.3 11.0 1.4e-55 187.1 7.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ40994.1 - 0.00051 19.7 12.2 0.00051 19.7 8.4 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 CBZ40994.1 - 0.0018 17.9 4.8 0.0018 17.9 3.4 1.8 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin family SUR7 PF06687.7 CBZ40994.1 - 0.26 10.7 13.7 2.7 7.5 3.2 3.0 3 0 0 3 3 3 0 SUR7/PalI family DUF4293 PF14126.1 CBZ40994.1 - 0.31 10.9 8.7 0.049 13.5 1.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF3754 PF12576.3 CBZ40994.1 - 0.99 9.0 3.2 0.53 9.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Amastin PF07344.6 CBZ40995.1 - 1.3e-46 158.0 10.6 1.5e-46 157.7 7.3 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ40995.1 - 2.4e-05 24.1 8.3 2.4e-05 24.1 5.7 1.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2417 PF10329.4 CBZ40995.1 - 8.2 5.7 8.4 3.9 6.8 0.1 2.3 1 1 0 2 2 2 0 Region of unknown function (DUF2417) Amastin PF07344.6 CBZ40996.1 - 5.7e-54 181.9 9.7 6.8e-54 181.6 6.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ40996.1 - 7.6e-05 22.4 8.2 7.6e-05 22.4 5.7 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Vpu PF00558.14 CBZ40996.1 - 0.22 11.1 0.2 0.22 11.1 0.1 2.8 3 0 0 3 3 3 0 Vpu protein Peptidase_C2 PF00648.16 CBZ40997.1 - 1.7e-55 188.1 0.0 2.3e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ40997.1 - 1.9e-21 75.9 0.2 3.6e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Amastin PF07344.6 CBZ40998.1 - 5.9e-50 168.8 9.2 7.1e-50 168.6 6.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Coprogen_oxidas PF01218.13 CBZ40998.1 - 0.12 10.8 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase Peptidase_C2 PF00648.16 CBZ40999.1 - 7.1e-56 189.3 0.0 9.7e-56 188.9 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.5 CBZ40999.1 - 1.9e-21 75.9 0.2 3.6e-21 75.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Amastin PF07344.6 CBZ41000.1 - 6e-51 172.1 8.5 7.3e-51 171.8 5.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ41000.1 - 0.043 13.5 17.2 0.094 12.3 11.0 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Oxidored_q2 PF00420.19 CBZ41000.1 - 0.19 11.3 3.1 2.3 7.8 2.1 2.6 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Amastin PF07344.6 CBZ41001.1 - 5.3e-50 169.0 10.0 6.4e-50 168.7 6.9 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF983 PF06170.7 CBZ41001.1 - 0.025 14.6 0.5 0.025 14.6 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF983) DUF21 PF01595.15 CBZ41001.1 - 5.5 6.2 6.2 0.89 8.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF21 Amastin PF07344.6 CBZ41002.1 - 2.6e-33 114.8 7.9 3.2e-33 114.5 5.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein SLAC1 PF03595.12 CBZ41002.1 - 0.00016 20.4 2.3 0.00021 20.0 1.6 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF983 PF06170.7 CBZ41002.1 - 0.013 15.6 0.5 0.013 15.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DUF4293 PF14126.1 CBZ41002.1 - 0.044 13.7 0.5 0.067 13.1 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) MFS_2 PF13347.1 CBZ41002.1 - 0.053 11.9 6.5 0.035 12.5 2.8 1.6 1 1 0 1 1 1 0 MFS/sugar transport protein Claudin_2 PF13903.1 CBZ41002.1 - 0.22 11.2 8.1 0.31 10.6 5.6 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF1469 PF07332.6 CBZ41002.1 - 2.5 7.8 8.5 0.32 10.7 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Reticulon PF02453.12 CBZ41002.1 - 4.4 6.8 9.2 36 3.8 6.4 1.9 1 1 0 1 1 1 0 Reticulon Peptidase_C2 PF00648.16 CBZ41003.1 - 7e-57 192.6 0.0 9.1e-57 192.3 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 CBZ41003.1 - 0.049 13.2 0.0 0.086 12.4 0.0 1.4 1 0 0 1 1 1 0 Calpain large subunit, domain III cNMP_binding PF00027.24 CBZ41005.1 - 2.4e-07 30.4 0.1 0.0009 19.0 0.0 3.5 2 2 0 2 2 2 2 Cyclic nucleotide-binding domain DUF3606 PF12244.3 CBZ41005.1 - 0.11 12.0 0.3 2.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Kinesin PF00225.18 CBZ41006.1 - 7.5e-24 84.0 0.0 7.5e-24 84.0 0.0 3.0 2 1 1 3 3 3 1 Kinesin motor domain Myosin_tail_1 PF01576.14 CBZ41006.1 - 8e-17 60.2 179.5 1.3e-13 49.6 41.4 4.8 1 1 2 3 3 3 2 Myosin tail Spc7 PF08317.6 CBZ41006.1 - 1.2e-08 34.0 138.9 0.0021 16.7 11.2 8.0 1 1 5 7 7 7 6 Spc7 kinetochore protein M PF02370.11 CBZ41006.1 - 4.3e-05 23.3 233.4 0.62 10.6 1.5 31.0 10 5 25 37 37 37 22 M protein repeat E2R135 PF11570.3 CBZ41006.1 - 6.2e-05 23.1 73.0 0.93 9.5 1.4 11.2 3 2 10 13 13 13 10 Coiled-coil receptor-binding R-domain of colicin E2 ATG16 PF08614.6 CBZ41006.1 - 0.00015 21.6 24.3 0.00015 21.6 16.8 8.7 1 1 7 8 8 8 5 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 CBZ41006.1 - 0.043 13.0 28.1 0.72 8.9 0.1 6.3 2 2 4 6 6 6 0 Reovirus sigma C capsid protein WXG100 PF06013.7 CBZ41006.1 - 0.053 13.5 90.6 5.6 7.0 0.6 16.4 5 3 13 18 18 18 0 Proteins of 100 residues with WXG Scaffolding_pro PF11418.3 CBZ41006.1 - 0.23 11.7 83.4 5.7 7.3 1.4 14.2 2 2 11 13 13 13 0 Phi29 scaffolding protein GAS PF13851.1 CBZ41006.1 - 2 7.5 162.5 0.22 10.7 10.2 9.0 1 1 8 10 10 10 0 Growth-arrest specific micro-tubule binding WD40 PF00400.27 CBZ41007.1 - 4.2e-58 191.2 27.3 4.1e-11 42.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 CBZ41007.1 - 3e-08 32.2 5.9 0.0044 15.2 0.2 3.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CBZ41007.1 - 8e-08 32.2 0.0 0.0001 22.0 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CBZ41007.1 - 4.4e-05 22.3 0.6 0.34 9.6 0.0 3.6 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 CBZ41007.1 - 0.00096 18.6 0.2 0.089 12.2 0.0 2.1 1 1 1 2 2 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 CBZ41007.1 - 0.029 12.6 0.0 0.79 7.9 0.0 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.7 CBZ41007.1 - 0.035 13.7 0.7 6.4 6.5 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 CBZ41007.1 - 0.16 10.1 0.0 0.51 8.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) WD40 PF00400.27 CBZ41008.1 - 4.4e-22 77.0 2.7 3.7e-10 39.2 0.2 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 CBZ41008.1 - 0.0003 19.0 0.1 0.0003 19.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Lectin_leg-like PF03388.8 CBZ41010.1 - 6.9e-11 41.7 0.0 9.5e-06 24.8 0.0 3.2 2 1 0 2 2 2 2 Legume-like lectin family Tbf5 PF06331.7 CBZ41011.1 - 0.034 13.9 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Ank_3 PF13606.1 CBZ41011.1 - 0.073 13.3 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat HTH_IclR PF09339.5 CBZ41012.1 - 0.0002 20.8 0.0 1 9.0 0.0 2.6 2 0 0 2 2 2 2 IclR helix-turn-helix domain Amastin PF07344.6 CBZ41013.1 - 4.3e-53 179.0 6.7 6.6e-53 178.4 4.7 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ41013.1 - 8.2 6.0 18.2 0.058 13.0 5.2 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBZ41015.1 - 3.4e-51 172.9 10.6 4.3e-51 172.5 7.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein KxDL PF10241.4 CBZ41016.1 - 0.00092 19.0 1.9 4.1 7.3 0.0 3.6 3 0 0 3 3 3 2 Uncharacterized conserved protein PBP_like PF12727.2 CBZ41016.1 - 0.024 13.5 1.1 6.1 5.7 0.1 2.6 2 0 0 2 2 2 0 PBP superfamily domain Med9 PF07544.8 CBZ41016.1 - 0.096 12.4 2.8 15 5.3 0.1 3.6 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Zip PF02535.17 CBZ41018.1 - 8.1e-24 84.1 11.9 9.1e-24 84.0 8.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Amastin PF07344.6 CBZ41019.1 - 1.4e-46 157.9 10.6 1.6e-46 157.7 7.3 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ41019.1 - 2.5e-05 24.0 8.3 2.5e-05 24.0 5.8 1.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2417 PF10329.4 CBZ41019.1 - 8.6 5.6 8.3 4 6.7 0.1 2.3 1 1 0 2 2 2 0 Region of unknown function (DUF2417) Mur_ligase PF01225.20 CBZ41022.1 - 0.029 14.4 44.2 1.5e+04 -35.0 30.6 12.7 1 1 0 1 1 1 0 Mur ligase family, catalytic domain LRR_4 PF12799.2 CBZ41023.1 - 1.1e-07 31.2 0.6 0.0023 17.5 0.2 3.1 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CBZ41023.1 - 1.4e-05 24.7 0.0 0.027 14.2 0.0 2.7 2 1 1 3 3 3 3 Leucine rich repeat DUF3338 PF11819.3 CBZ41023.1 - 0.042 13.2 0.0 11 5.5 0.0 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF3338) Transposase_22 PF02994.9 CBZ41024.1 - 0.01 14.3 0.1 0.019 13.5 0.1 1.3 1 0 0 1 1 1 0 L1 transposable element Per1 PF04080.8 CBZ41024.1 - 0.012 15.0 0.1 0.014 14.8 0.1 1.1 1 0 0 1 1 1 0 Per1-like DUF1515 PF07439.6 CBZ41024.1 - 0.08 12.7 4.5 0.46 10.3 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) DUF948 PF06103.6 CBZ41024.1 - 0.11 12.3 2.4 0.33 10.8 1.5 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Amastin PF07344.6 CBZ41025.1 - 1.2e-51 174.3 7.2 1.4e-51 174.1 5.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ41025.1 - 3.3e-06 26.8 4.6 3.3e-06 26.8 3.2 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 CBZ41026.1 - 7.7e-54 181.5 10.1 9.2e-54 181.2 7.0 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ41026.1 - 0.0002 21.0 9.1 0.0002 21.0 6.3 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Vpu PF00558.14 CBZ41026.1 - 0.22 11.1 0.2 0.22 11.1 0.1 2.6 3 0 0 3 3 3 0 Vpu protein Peptidase_C2 PF00648.16 CBZ41027.1 - 3.3e-37 128.0 0.0 5e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease IMS PF00817.15 CBZ41028.1 - 2.8e-32 111.5 0.2 3.5e-32 111.2 0.1 1.1 1 0 0 1 1 1 1 impB/mucB/samB family TIP39 PF14980.1 CBZ41028.1 - 0.2 11.3 1.1 0.26 10.9 0.1 1.6 2 0 0 2 2 2 0 TIP39 peptide IMS PF00817.15 CBZ41029.1 - 6.1e-41 139.6 0.4 8.6e-41 139.1 0.3 1.2 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CBZ41029.1 - 2.6e-06 27.3 0.0 5.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CBZ41029.1 - 0.0026 17.7 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 IMS family HHH motif BT1 PF03092.11 CBZ41030.1 - 5.2e-197 654.8 5.0 6e-197 654.6 3.5 1.0 1 0 0 1 1 1 1 BT1 family LRR_8 PF13855.1 CBZ41031.1 - 7.3e-07 28.8 0.3 0.0046 16.6 0.2 2.8 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 CBZ41031.1 - 8.5e-07 28.4 0.0 0.031 13.8 0.0 3.3 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.7 CBZ41031.1 - 0.07 13.0 0.1 0.07 13.0 0.1 2.7 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain ATP-synt_ab PF00006.20 CBZ41032.1 - 6.5e-69 231.7 0.1 9.6e-69 231.1 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain His_kinase PF06580.8 CBZ41032.1 - 0.064 13.1 2.0 6 6.8 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase ATP-synt_ab_C PF00306.22 CBZ41032.1 - 0.096 13.1 0.0 0.31 11.5 0.0 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain ECH_C PF13766.1 CBZ41033.1 - 6.9e-24 84.2 0.0 1.1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 CBZ41033.1 - 4.3e-13 48.9 0.0 6.6e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Tubulin_C PF03953.12 CBZ41034.1 - 2e-34 118.3 0.0 2.6e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 CBZ41035.1 - 6.9e-68 228.6 0.0 8.6e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CBZ41035.1 - 2.2e-07 30.9 0.1 4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CBZ41035.1 - 0.0053 16.2 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain ELO PF01151.13 CBZ41036.1 - 1.2e-56 191.8 14.2 1.8e-56 191.2 9.8 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.13 CBZ41037.1 - 1.7e-71 240.4 20.1 2.4e-71 239.9 13.9 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family UTRA PF07702.8 CBZ41037.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 UTRA domain ELO PF01151.13 CBZ41038.1 - 1.1e-68 231.2 19.5 1.5e-68 230.8 13.5 1.2 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4018 PF13210.1 CBZ41039.1 - 0.032 13.6 0.4 0.032 13.6 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) ATP-synt_C PF00137.16 CBZ41039.1 - 0.061 13.2 7.5 3.9 7.4 0.8 3.3 3 0 0 3 3 3 0 ATP synthase subunit C MrpF_PhaF PF04066.8 CBZ41039.1 - 0.13 12.5 1.4 3.1 8.1 0.1 2.8 2 0 0 2 2 2 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) Amastin PF07344.6 CBZ41042.1 - 4.6e-48 162.7 9.3 5.4e-48 162.5 6.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 CBZ41042.1 - 0.046 13.3 5.9 0.065 12.8 4.1 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF975 PF06161.6 CBZ41042.1 - 0.8 9.3 5.4 0.086 12.5 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF975) DUF1218 PF06749.7 CBZ41042.1 - 6.7 7.2 12.7 0.6 10.6 1.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1218) DUF2721 PF11026.3 CBZ41042.1 - 7.9 6.1 10.3 20 4.7 5.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) TrbC PF04956.8 CBZ41042.1 - 8.4 6.4 10.2 0.58 10.2 0.1 2.7 2 1 1 3 3 3 0 TrbC/VIRB2 family Amastin PF07344.6 CBZ41043.1 - 2.9e-49 166.6 11.6 3.4e-49 166.4 8.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 CBZ41043.1 - 0.033 13.8 10.3 0.044 13.4 7.2 1.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF1218 PF06749.7 CBZ41043.1 - 0.58 10.6 13.9 0.28 11.6 1.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Claudin_2 PF13903.1 CBZ41043.1 - 1.1 8.9 16.0 0.24 11.0 8.6 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Pkinase PF00069.20 CBZ41045.1 - 4.9e-64 215.9 0.0 6.1e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CBZ41045.1 - 2.2e-26 92.5 0.0 3.2e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CBZ41045.1 - 2.4e-09 36.5 0.0 4.8e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CBZ41045.1 - 0.00053 19.1 0.6 0.0013 17.8 0.4 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CBZ41045.1 - 0.0068 16.1 0.3 0.2 11.3 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CBZ41045.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family His_Phos_2 PF00328.17 CBZ41046.1 - 0.036 13.4 0.0 0.036 13.4 0.0 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Amastin PF07344.6 CBZ41047.1 - 2.5e-53 179.8 7.1 3e-53 179.5 4.9 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein CD20 PF04103.10 CBZ41047.1 - 0.00028 20.8 0.0 0.012 15.5 0.0 2.3 1 1 1 2 2 2 1 CD20-like family Claudin_2 PF13903.1 CBZ41047.1 - 0.0034 17.1 8.5 0.0034 17.1 5.9 2.2 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF975 PF06161.6 CBZ41047.1 - 0.63 9.7 4.4 0.12 12.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF975) Baculo_11_kDa PF06143.6 CBZ41047.1 - 5.2 6.5 0.0 5.2 6.5 0.0 3.3 2 1 1 3 3 3 0 Baculovirus 11 kDa family Peptidase_C1 PF00112.18 CBZ41048.1 - 5e-72 242.3 0.7 5e-72 242.3 0.5 1.9 2 0 0 2 2 2 1 Papain family cysteine protease DUF3586 PF12131.3 CBZ41048.1 - 5e-27 93.7 8.3 1.1e-26 92.6 5.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3586) Peptidase_C1_2 PF03051.10 CBZ41048.1 - 5e-06 25.2 0.2 0.00038 19.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Amastin PF07344.6 CBZ41050.1 - 1.8e-48 164.0 13.1 1.8e-48 164.0 9.1 2.0 3 0 0 3 3 3 1 Amastin surface glycoprotein Claudin_2 PF13903.1 CBZ41050.1 - 0.71 9.5 17.1 0.074 12.7 7.7 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Aa_trans PF01490.13 CBZ41052.1 - 5.9e-46 156.7 18.6 7.2e-46 156.4 12.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CBZ41052.1 - 4.2e-09 35.7 9.4 4.2e-09 35.7 6.5 2.5 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family