# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUF2946 PF11162.8 CBZ31089.1 - 2.3e-19 70.1 3.4 4.3e-19 69.3 3.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2946) Shisa PF13908.6 CBZ31089.1 - 0.00029 21.1 0.0 0.00078 19.7 0.0 1.7 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Prominin PF05478.11 CBZ31089.1 - 0.0081 14.2 1.3 0.012 13.7 1.3 1.1 1 0 0 1 1 1 1 Prominin WBP-1 PF11669.8 CBZ31089.1 - 0.028 15.1 0.3 0.075 13.7 0.3 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 EphA2_TM PF14575.6 CBZ31089.1 - 0.028 15.3 0.1 0.084 13.8 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 CBZ31089.1 - 0.045 14.0 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Hum_adeno_E3A PF05393.11 CBZ31089.1 - 0.057 13.4 1.2 0.14 12.2 1.2 1.6 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein TMIE PF16038.5 CBZ31089.1 - 0.065 13.1 2.0 0.11 12.3 2.0 1.4 1 0 0 1 1 1 0 TMIE protein SIT PF15330.6 CBZ31089.1 - 0.067 13.6 0.0 0.26 11.7 0.0 1.8 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM52 PF14979.6 CBZ31089.1 - 0.095 12.6 1.0 0.22 11.5 1.0 1.5 1 0 0 1 1 1 0 Transmembrane 52 Tweety PF04906.13 CBZ31089.1 - 0.22 10.2 3.8 0.23 10.1 0.3 2.0 2 0 0 2 2 2 0 Tweety Rhabdo_glycop PF00974.18 CBZ31089.1 - 0.69 8.3 3.9 0.52 8.7 2.0 1.6 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein ATP1G1_PLM_MAT8 PF02038.16 CBZ31089.1 - 2.3 7.7 4.3 1.3 8.6 1.3 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Exo_endo_phos PF03372.23 CBZ31090.1 - 6e-07 29.2 0.0 1.3e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Kinesin PF00225.23 CBZ31091.1 - 7.4e-94 314.4 0.0 9.5e-94 314.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ31091.1 - 8.7e-15 54.9 0.0 1.8e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Arg_decarbox_C PF17944.1 CBZ31091.1 - 0.035 14.7 1.8 0.12 13.0 0.6 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension SAM_1 PF00536.30 CBZ31091.1 - 0.057 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) AAA_16 PF13191.6 CBZ31091.1 - 0.082 13.3 0.9 0.29 11.5 0.0 2.3 2 2 0 2 2 2 0 AAA ATPase domain Dockerin_1 PF00404.18 CBZ31091.1 - 0.16 12.2 3.1 0.11 12.7 1.0 1.9 2 0 0 2 2 2 0 Dockerin type I domain BLOC1_2 PF10046.9 CBZ31091.1 - 0.51 10.7 2.8 1.6 9.1 2.8 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GYF PF02213.16 CBZ31092.1 - 0.00047 19.8 0.3 0.001 18.7 0.3 1.5 1 0 0 1 1 1 1 GYF domain Rotamase_3 PF13616.6 CBZ31092.1 - 0.034 14.7 0.0 0.052 14.1 0.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain CPSase_L_D2 PF02786.17 CBZ31093.1 - 6.3e-77 257.8 0.6 1.3e-76 256.8 0.6 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBZ31093.1 - 8.4e-43 145.4 0.3 2.5e-42 143.9 0.1 1.9 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBZ31093.1 - 2e-35 121.1 0.0 6e-35 119.6 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBZ31093.1 - 1.1e-17 63.6 4.7 1.2e-17 63.5 2.4 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.22 CBZ31093.1 - 7.4e-09 35.4 0.9 2e-08 34.0 0.3 1.9 2 0 0 2 2 2 1 ATP-grasp domain PCC_BT PF18140.1 CBZ31093.1 - 1.2e-08 35.4 0.1 3.4e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Dala_Dala_lig_C PF07478.13 CBZ31093.1 - 4.3e-06 26.4 0.4 1e-05 25.2 0.4 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 CBZ31093.1 - 1.7e-05 24.6 0.5 0.011 15.5 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 CBZ31093.1 - 9.6e-05 23.0 0.3 0.04 14.6 0.0 2.7 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 CBZ31093.1 - 0.00046 19.5 0.4 0.14 11.4 0.1 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_3 PF02655.14 CBZ31093.1 - 0.00072 19.6 0.2 0.0013 18.8 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CBZ31093.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 CBZ31093.1 - 0.011 15.0 0.1 0.031 13.5 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 CBZ31093.1 - 0.021 14.7 0.6 0.052 13.4 0.6 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 CBZ31093.1 - 0.023 14.6 0.3 0.086 12.8 0.3 2.0 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Spc7 PF08317.11 CBZ31094.1 - 1.1 8.1 8.1 1.7 7.4 8.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein BSD PF03909.17 CBZ31095.1 - 1.7e-07 31.1 0.0 3.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 BSD domain Glyco_transf_11 PF01531.16 CBZ31097.1 - 2.2e-11 43.5 0.5 5.2e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 11 Glutaredoxin PF00462.24 CBZ31098.1 - 3.9e-17 62.2 0.2 7.6e-17 61.3 0.1 1.6 2 0 0 2 2 2 1 Glutaredoxin DUF5427 PF10310.9 CBZ31099.1 - 5.6 5.8 8.1 11 4.8 8.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5427) KIAA1328 PF15369.6 CBZ31100.1 - 2 8.1 7.3 2.8 7.7 7.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Par3_HAL_N_term PF12053.8 CBZ31101.1 - 0.00026 21.1 0.0 0.00032 20.8 0.0 1.1 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins LSM PF01423.22 CBZ31103.1 - 7e-10 38.5 0.0 8.3e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain Voltage_CLC PF00654.20 CBZ31105.1 - 6.3e-90 302.0 33.6 1.7e-89 300.6 28.7 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 CBZ31105.1 - 7.6e-05 23.1 0.0 0.099 13.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF2967 PF11179.8 CBZ31106.1 - 0.068 11.3 1.2 0.077 11.1 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) LMWPc PF01451.21 CBZ31107.1 - 5.1e-06 26.9 0.0 8.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CUE PF02845.16 CBZ31108.1 - 2.1e-11 43.3 0.0 1.9e-05 24.2 0.0 4.2 4 0 0 4 4 4 2 CUE domain Smr PF01713.21 CBZ31108.1 - 1.1e-09 38.4 0.9 3.8e-09 36.8 0.9 2.0 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 CBZ31108.1 - 4.3e-09 36.6 0.3 4.3e-09 36.6 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) UBA PF00627.31 CBZ31108.1 - 4.4e-06 26.5 2.0 0.01 15.7 0.1 3.3 4 0 0 4 4 4 2 UBA/TS-N domain zf_CCCH_4 PF18345.1 CBZ31108.1 - 1.6e-05 24.8 25.9 0.061 13.4 4.9 4.8 4 1 0 4 4 4 4 Zinc finger domain zf-CCCH_4 PF18044.1 CBZ31108.1 - 5.7 6.9 26.9 0.092 12.6 2.7 4.4 4 1 0 4 4 4 0 CCCH-type zinc finger Pro_isomerase PF00160.21 CBZ31109.1 - 8.6e-38 130.1 0.0 1.2e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HDPD PF02924.14 CBZ31109.1 - 0.049 13.7 0.0 0.072 13.2 0.0 1.4 1 1 0 1 1 1 0 Bacteriophage lambda head decoration protein D SNF2_N PF00176.23 CBZ31111.1 - 3.3e-35 121.4 0.0 4.7e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ31111.1 - 2.1e-15 57.0 0.0 4.1e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ31111.1 - 0.00079 19.5 0.0 0.0029 17.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBZ31111.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Beta_helix PF13229.6 CBZ31112.1 - 5e-10 39.4 0.1 1.2e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 CBZ31112.1 - 4.1e-06 26.2 0.0 6.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Enkurin PF13864.6 CBZ31113.1 - 2e-19 69.9 9.9 2e-19 69.9 9.9 2.1 2 0 0 2 2 2 1 Calmodulin-binding Nore1-SARAH PF16517.5 CBZ31113.1 - 0.59 10.1 5.7 1.2 9.1 0.6 2.7 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Med3 PF11593.8 CBZ31113.1 - 2.1 7.5 5.3 1.3 8.2 3.5 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Thioredoxin PF00085.20 CBZ31114.1 - 6.3e-20 71.1 0.1 7.6e-20 70.8 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBZ31114.1 - 0.00037 20.8 0.1 0.044 14.1 0.1 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CBZ31114.1 - 0.0011 19.4 0.2 0.0047 17.4 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CBZ31114.1 - 0.0023 17.8 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 CBZ31114.1 - 0.0072 15.7 0.0 0.0073 15.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 CBZ31114.1 - 0.023 14.6 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Phosducin PF02114.16 CBZ31114.1 - 0.074 12.0 0.0 0.078 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin Thioredoxin_7 PF13899.6 CBZ31114.1 - 0.078 13.2 0.4 0.14 12.4 0.4 1.6 1 1 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 CBZ31114.1 - 0.08 13.2 0.3 0.16 12.2 0.3 1.6 1 0 0 1 1 1 0 Glutaredoxin PseudoU_synth_2 PF00849.22 CBZ31115.1 - 3.4e-22 79.3 0.0 1.6e-21 77.1 0.0 2.0 2 1 0 2 2 2 1 RNA pseudouridylate synthase Cmc1 PF08583.10 CBZ31116.1 - 6.6e-06 26.1 2.6 1.2e-05 25.3 2.6 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 CBZ31116.1 - 0.0051 16.8 3.4 0.0094 15.9 3.4 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 CBZ31116.1 - 0.043 14.2 0.2 0.11 12.9 0.2 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 CBZ31116.1 - 0.82 9.9 4.3 2.4 8.4 0.5 2.3 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein 4F5 PF04419.14 CBZ31117.1 - 7.8e-12 45.9 12.3 7.8e-12 45.9 12.3 2.0 2 0 0 2 2 2 1 4F5 protein family DHHA2 PF02833.14 CBZ31118.1 - 2.3e-20 73.3 0.0 1.6e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 CBZ31118.1 - 2.1e-09 37.5 0.0 3.6e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 DHH family RSS_P20 PF11757.8 CBZ31118.1 - 0.21 12.0 0.1 10 6.6 0.0 2.3 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain WD40 PF00400.32 CBZ31120.1 - 2.2e-06 28.3 10.9 0.03 15.2 0.2 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat PQQ_3 PF13570.6 CBZ31120.1 - 0.0084 16.6 0.5 8.4 7.0 0.1 4.1 4 0 0 4 4 4 1 PQQ-like domain ANAPC4_WD40 PF12894.7 CBZ31120.1 - 0.056 13.8 0.0 33 4.9 0.0 3.8 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain MPC PF03650.13 CBZ31122.1 - 6.9e-16 58.4 0.4 8e-16 58.2 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers TFIIA PF03153.13 CBZ31124.1 - 1.3 9.0 9.9 1.8 8.5 9.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1451 PF07295.11 CBZ31124.1 - 3.5 7.7 7.1 3.8 7.5 3.7 2.3 1 1 1 2 2 2 0 Zinc-ribbon containing domain TMEM208_SND2 PF05620.11 CBZ31126.1 - 2e-33 115.5 0.0 2.2e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Dymeclin PF09742.9 CBZ31127.1 - 1.2e-49 169.4 0.0 1.5e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 CBZ31127.1 - 0.037 12.2 1.5 5.5 5.0 0.1 2.8 3 0 0 3 3 3 0 High-temperature-induced dauer-formation protein AAR2 PF05282.11 CBZ31127.1 - 0.21 10.9 3.4 1 8.7 0.0 2.5 3 0 0 3 3 3 0 AAR2 protein DUF1664 PF07889.12 CBZ31128.1 - 0.016 15.3 1.4 0.016 15.3 1.4 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_S7e PF01251.18 CBZ31130.1 - 6.1e-23 81.5 0.4 6.7e-23 81.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Ribosomal_S7e PF01251.18 CBZ31131.1 - 8.7e-64 214.7 3.9 9.9e-64 214.5 3.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e zf-UBP PF02148.19 CBZ31132.1 - 8.8e-10 38.8 9.9 8.8e-10 38.8 9.9 2.5 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CBZ31132.1 - 7e-08 32.7 7.8 7e-08 32.7 7.8 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ31132.1 - 2.8e-06 27.0 9.2 2.8e-06 27.0 9.2 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBZ31132.1 - 0.00097 19.0 16.5 0.005 16.7 3.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ31132.1 - 0.0014 18.8 4.7 0.0014 18.8 4.7 2.5 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBZ31132.1 - 0.0017 18.3 6.9 0.0017 18.3 6.9 2.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 CBZ31132.1 - 0.01 15.6 6.1 0.01 15.6 6.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 CBZ31132.1 - 0.016 15.1 8.3 0.016 15.1 8.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ31132.1 - 0.059 13.4 14.4 0.023 14.7 4.7 2.7 1 1 1 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 CBZ31132.1 - 0.085 12.9 2.0 0.32 11.1 2.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RecR PF02132.15 CBZ31132.1 - 0.43 10.2 9.3 0.16 11.6 0.7 3.0 3 0 0 3 3 3 0 RecR protein DUF2852 PF11014.8 CBZ31132.1 - 0.92 9.7 6.3 3 8.0 0.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) MFS_5 PF05631.14 CBZ31133.1 - 7.2e-09 35.0 7.5 4.2e-06 25.9 0.9 2.4 2 1 0 2 2 2 2 Sugar-tranasporters, 12 TM Isochorismatase PF00857.20 CBZ31134.1 - 1e-25 90.9 0.0 1.2e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family AAA_18 PF13238.6 CBZ31135.1 - 2.2e-05 25.0 0.1 0.00011 22.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ31135.1 - 3.3e-05 24.3 0.0 8.4e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 CBZ31135.1 - 0.0028 18.1 0.0 0.0052 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain mRNA_cap_C PF03919.15 CBZ31135.1 - 0.047 14.3 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain AAA PF00004.29 CBZ31135.1 - 0.048 14.1 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 CBZ31135.1 - 0.068 12.8 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase NB-ARC PF00931.22 CBZ31135.1 - 0.09 11.9 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.10 CBZ31135.1 - 0.17 11.3 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AMP-binding PF00501.28 CBZ31136.1 - 1.2e-89 300.8 0.0 1.7e-89 300.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Beta_elim_lyase PF01212.21 CBZ31137.1 - 1.2e-34 119.9 0.0 1.5e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CBZ31137.1 - 1.7e-11 43.7 0.0 2.5e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CBZ31137.1 - 1.7e-09 37.4 0.0 1.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.19 CBZ31137.1 - 0.0016 17.2 0.0 0.0033 16.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 CBZ31137.1 - 0.046 13.0 0.1 0.065 12.5 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.28 CBZ31138.1 - 1.9e-97 326.6 0.0 2.5e-97 326.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 CBZ31139.1 - 1.4e-77 261.1 0.0 2e-77 260.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme TIG_plexin PF17960.1 CBZ31139.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 TIG domain AMP-binding PF00501.28 CBZ31141.1 - 1.9e-95 319.9 0.1 2.8e-95 319.4 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF4476 PF14771.6 CBZ31141.1 - 0.013 15.8 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) AMP-binding PF00501.28 CBZ31142.1 - 1.3e-42 145.9 0.4 5.8e-23 81.2 0.1 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Caps_synth_CapC PF14102.6 CBZ31144.1 - 0.12 12.8 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 Capsule biosynthesis CapC PRP3 PF08572.10 CBZ31145.1 - 3.8e-14 53.0 0.6 3.9e-13 49.7 0.3 2.2 1 1 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CBZ31145.1 - 3.6e-13 49.8 0.0 1.2e-12 48.2 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1115) SMYLE_N PF18615.1 CBZ31145.1 - 0.027 14.0 0.2 0.027 14.0 0.2 1.7 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain MTBP_N PF14918.6 CBZ31145.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 MDM2-binding hGDE_N PF14699.6 CBZ31145.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme Mtc PF03820.17 CBZ31146.1 - 4.8e-84 282.0 0.2 5.4e-84 281.9 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier RNA_ligase PF09414.10 CBZ31148.1 - 2.8e-21 76.5 0.0 4.3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 RNA ligase T4_Rnl2_C PF18043.1 CBZ31148.1 - 1.9e-06 27.9 0.0 3.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal RabGAP-TBC PF00566.18 CBZ31149.1 - 1.8e-25 89.8 0.0 8e-12 45.3 0.2 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain AUX_IAA PF02309.16 CBZ31149.1 - 0.43 10.4 1.6 0.56 10.0 0.1 1.9 2 0 0 2 2 2 0 AUX/IAA family Asp_protease PF09668.10 CBZ31150.1 - 7.4e-59 197.0 0.7 9.7e-59 196.6 0.7 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CBZ31150.1 - 5.8e-17 62.0 0.0 9.9e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CBZ31150.1 - 7.8e-07 29.7 0.0 1.6e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease UBA_4 PF14555.6 CBZ31150.1 - 1.1e-05 25.2 0.3 2.2e-05 24.2 0.1 1.7 2 0 0 2 2 2 1 UBA-like domain RVP_2 PF08284.11 CBZ31150.1 - 0.00034 20.4 0.0 0.00053 19.8 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CBZ31150.1 - 0.016 15.5 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease EF-hand_1 PF00036.32 CBZ31151.1 - 0.011 15.2 0.0 0.036 13.6 0.0 1.8 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 CBZ31151.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair HSP70 PF00012.20 CBZ31153.1 - 8.9e-28 96.8 1.4 4.2e-24 84.7 0.2 3.9 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CBZ31153.1 - 0.0024 16.8 0.9 0.0042 16.0 0.9 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peptidase_M16 PF00675.20 CBZ31154.1 - 5.1e-40 136.9 0.1 1.4e-39 135.4 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBZ31154.1 - 1.9e-15 57.4 0.0 1.1e-13 51.6 0.0 3.0 3 1 0 3 3 3 1 Peptidase M16 inactive domain DUF4795 PF16043.5 CBZ31154.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) ORC2 PF04084.14 CBZ31155.1 - 2.2e-05 23.6 0.0 0.11 11.4 0.0 2.2 2 0 0 2 2 2 2 Origin recognition complex subunit 2 PLAC8 PF04749.17 CBZ31158.1 - 1.5e-13 51.5 12.6 2.8e-13 50.7 12.6 1.5 1 1 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 CBZ31159.1 - 2.2e-09 38.2 6.3 2.5e-08 34.8 6.3 2.3 1 1 0 1 1 1 1 PLAC8 family ThiF PF00899.21 CBZ31160.1 - 2.3e-82 276.1 0.0 9e-82 274.1 0.0 1.7 1 1 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CBZ31160.1 - 0.085 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GGDEF_2 PF17853.1 CBZ31160.1 - 0.14 12.4 1.0 0.54 10.5 0.0 2.5 4 0 0 4 4 4 0 GGDEF-like domain C2 PF00168.30 CBZ31162.1 - 0.00041 20.6 0.0 0.0015 18.8 0.0 2.0 1 1 0 1 1 1 1 C2 domain DUF4478 PF14793.6 CBZ31162.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases DUF4719 PF15843.5 CBZ31163.1 - 0.78 9.8 5.6 2.6 8.1 5.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) DUF4407 PF14362.6 CBZ31163.1 - 2.4 7.5 11.2 3.6 6.8 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop53 PF07767.11 CBZ31163.1 - 3.7 6.8 17.9 5.5 6.3 17.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PGA2 PF07543.12 CBZ31163.1 - 7.3 6.6 14.9 14 5.6 14.9 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Pkinase PF00069.25 CBZ31164.1 - 5.6e-19 68.5 0.0 3.5e-07 29.9 0.0 3.5 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31164.1 - 0.053 12.8 0.0 0.42 9.9 0.0 2.3 3 0 0 3 3 3 0 Protein tyrosine kinase DEAD PF00270.29 CBZ31166.1 - 3.2e-42 144.3 0.1 8.8e-42 142.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ31166.1 - 5.5e-29 100.7 0.3 3.2e-28 98.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CBZ31166.1 - 4.4e-05 23.0 0.1 0.00014 21.3 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CBZ31166.1 - 0.073 13.3 0.9 0.4 11.0 0.9 2.4 1 1 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.6 CBZ31168.1 - 0.0086 16.8 2.0 0.021 15.7 2.0 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger CpXC PF14353.6 CBZ31168.1 - 0.051 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 CpXC protein zinc_ribbon_9 PF14369.6 CBZ31168.1 - 0.09 13.0 0.3 0.23 11.7 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon Nudix_N_2 PF14803.6 CBZ31168.1 - 0.19 11.7 2.7 0.17 11.8 0.5 2.1 2 0 0 2 2 2 0 Nudix N-terminal zf-C2H2_6 PF13912.6 CBZ31168.1 - 0.28 11.2 0.7 0.54 10.3 0.7 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger GIT_CC PF16559.5 CBZ31168.1 - 0.33 10.9 0.7 0.58 10.1 0.7 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2514 PF10721.9 CBZ31168.1 - 2 8.4 14.4 6.8 6.7 8.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) BK_channel_a PF03493.18 CBZ31169.1 - 5.4e-13 49.0 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 CBZ31169.1 - 2.1e-10 40.4 4.6 2.1e-10 40.4 4.6 2.0 2 0 0 2 2 2 1 Ion channel SR-25 PF10500.9 CBZ31169.1 - 0.025 14.2 2.6 0.043 13.4 2.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF962 PF06127.11 CBZ31169.1 - 0.39 10.8 2.8 1.1 9.4 2.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF962) Ion_trans_2 PF07885.16 CBZ31170.1 - 1.2e-11 44.4 5.6 4.2e-11 42.7 5.6 1.9 1 0 0 1 1 1 1 Ion channel BK_channel_a PF03493.18 CBZ31170.1 - 1.9e-05 24.8 0.0 5.8e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Cyt-b5 PF00173.28 CBZ31172.1 - 6e-41 138.4 0.3 3.2e-20 72.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain K1 PF02960.14 CBZ31172.1 - 0.016 15.3 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 K1 glycoprotein DUF1178 PF06676.11 CBZ31175.1 - 0.079 13.4 0.0 0.46 10.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) SelR PF01641.18 CBZ31176.1 - 0.017 15.2 0.2 0.49 10.5 0.0 2.5 2 1 0 2 2 2 0 SelR domain SRP14 PF02290.15 CBZ31177.1 - 0.17 12.2 1.0 1.5 9.2 0.1 2.6 3 0 0 3 3 3 0 Signal recognition particle 14kD protein Torus PF16131.5 CBZ31178.1 - 0.0016 19.1 2.1 1.1 10.0 0.3 2.7 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 CBZ31178.1 - 1.4 9.0 14.4 4.3 7.4 2.3 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Xpo1 PF08389.12 CBZ31179.1 - 2.4e-24 86.1 0.3 1.2e-22 80.5 0.1 3.0 3 0 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.6 CBZ31179.1 - 0.046 14.1 1.9 32 5.0 0.0 4.3 2 1 0 3 3 3 0 HEAT repeats Herpes_capsid PF06112.11 CBZ31179.1 - 6 6.9 11.1 21 5.1 11.1 2.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PI3_PI4_kinase PF00454.27 CBZ31180.1 - 3e-41 141.9 0.0 4.5e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CBZ31180.1 - 0.0002 21.1 1.1 0.00029 20.6 0.1 2.0 2 0 0 2 2 2 1 FATC domain DUF3322 PF11795.8 CBZ31180.1 - 0.3 11.1 5.5 2.4 8.1 2.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) SF3A2 PF16835.5 CBZ31181.1 - 8e-23 80.6 0.0 1.2e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CBZ31181.1 - 0.00061 20.1 0.2 0.0015 18.9 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBZ31181.1 - 0.0035 17.6 0.1 0.0069 16.6 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C3HC4_3 PF13920.6 CBZ31182.1 - 1.1e-07 31.6 7.4 1.9e-07 30.8 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ31182.1 - 0.0011 19.2 9.8 0.0021 18.4 9.8 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ31182.1 - 0.0061 16.4 9.6 0.012 15.4 9.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBZ31182.1 - 0.068 13.1 8.9 0.14 12.2 8.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBZ31182.1 - 5.5 7.2 8.9 17 5.7 8.9 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Vps51 PF08700.11 CBZ31183.1 - 3.4e-10 39.9 0.0 1.4e-09 37.9 0.0 2.0 2 0 0 2 2 2 1 Vps51/Vps67 DUF599 PF04654.12 CBZ31183.1 - 0.045 13.2 1.9 0.14 11.6 1.9 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF599 Galactosyl_T PF01762.21 CBZ31187.1 - 0.00054 19.8 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase O-FucT PF10250.9 CBZ31189.1 - 0.00069 19.4 0.2 0.99 9.0 0.0 2.2 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Galactosyl_T PF01762.21 CBZ31190.1 - 0.023 14.5 0.0 0.063 13.1 0.0 1.7 1 0 0 1 1 1 0 Galactosyltransferase GlcNAc PF11397.8 CBZ31191.1 - 1.6e-143 478.5 0.0 2.2e-143 478.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) GlcNAc PF11397.8 CBZ31192.1 - 5.3e-06 26.1 0.1 0.049 13.1 0.0 2.8 2 1 0 2 2 2 2 Glycosyltransferase (GlcNAc) Ras PF00071.22 CBZ31193.1 - 7.8e-53 178.4 0.1 9.3e-53 178.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ31193.1 - 3.5e-37 127.3 0.0 5e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ31193.1 - 7.5e-15 54.8 0.0 9.3e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ31193.1 - 2.4e-05 23.8 0.1 3.1e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBZ31193.1 - 8.5e-05 22.2 0.1 0.0002 21.0 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ31193.1 - 0.00073 19.5 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CBZ31193.1 - 0.00077 18.9 0.0 0.0013 18.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBZ31193.1 - 0.0022 18.1 0.0 0.0045 17.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ31193.1 - 0.0083 15.7 0.0 0.65 9.5 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B TniB PF05621.11 CBZ31193.1 - 0.013 14.9 0.0 0.064 12.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 CBZ31193.1 - 0.016 14.8 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CBZ31193.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CBZ31193.1 - 0.16 11.7 0.1 9.1 6.0 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF913 PF06025.12 CBZ31193.1 - 0.16 10.9 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DLIC PF05783.11 CBZ31193.1 - 3.1 6.5 4.7 0.8 8.5 0.0 1.9 1 1 1 2 2 2 0 Dynein light intermediate chain (DLIC) UPF0158 PF03682.13 CBZ31194.1 - 0.033 14.1 0.0 0.033 14.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Macoilin PF09726.9 CBZ31195.1 - 0.82 8.2 3.3 0.81 8.2 3.3 1.1 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 CBZ31196.1 - 2.6e-46 158.1 0.0 1.1e-45 156.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31196.1 - 1.3e-29 103.2 0.0 1.8e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ31196.1 - 1.1e-07 31.5 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ31196.1 - 7.7e-06 24.9 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ31196.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC2_membrane_3 PF12698.7 CBZ31197.1 - 4.8e-62 210.1 41.7 1.7e-37 129.3 13.7 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ31197.1 - 1.4e-49 168.1 0.0 1.2e-23 84.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ31197.1 - 8.8e-15 55.3 8.8 9.7e-05 22.3 0.0 5.2 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ31197.1 - 5e-07 30.4 4.1 8.6e-05 23.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 CBZ31197.1 - 5e-06 26.2 0.1 0.00089 18.9 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 CBZ31197.1 - 2e-05 24.1 0.0 3.7 6.9 0.0 4.2 4 1 0 5 5 5 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBZ31197.1 - 0.0012 18.8 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CBZ31197.1 - 0.029 14.5 0.1 0.68 10.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 CBZ31197.1 - 0.032 14.5 3.0 6.8 6.9 0.0 3.9 3 0 0 3 3 3 0 AAA domain MukB PF04310.12 CBZ31197.1 - 0.04 13.7 0.4 7.9 6.2 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_27 PF13514.6 CBZ31197.1 - 0.05 13.2 0.0 1.5 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 CBZ31197.1 - 0.059 13.0 0.4 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF4162 PF13732.6 CBZ31197.1 - 0.065 14.0 0.0 5.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) DUF87 PF01935.17 CBZ31197.1 - 0.15 12.1 0.9 0.52 10.4 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_15 PF13175.6 CBZ31197.1 - 0.16 11.6 0.0 6.6 6.3 0.0 2.9 4 0 0 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 CBZ31197.1 - 0.2 11.9 0.3 6.2 7.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain LapA_dom PF06305.11 CBZ31197.1 - 0.24 11.2 3.2 0.91 9.4 1.6 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain ABC2_membrane PF01061.24 CBZ31197.1 - 2.2 7.6 52.9 0.2 11.1 24.9 3.9 4 1 0 4 4 4 0 ABC-2 type transporter SNAP PF14938.6 CBZ31198.1 - 8.1e-14 51.7 14.6 9.9e-11 41.6 6.9 3.2 3 0 0 3 3 3 2 Soluble NSF attachment protein, SNAP DHR-2 PF06920.13 CBZ31198.1 - 0.00025 19.8 0.1 0.00035 19.4 0.1 1.1 1 0 0 1 1 1 1 Dock homology region 2 FAM70 PF14967.6 CBZ31198.1 - 4.1 6.8 6.1 2.3 7.6 2.2 2.2 2 0 0 2 2 2 0 FAM70 protein RNase_PH PF01138.21 CBZ31199.1 - 7e-18 65.4 0.0 1.4e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Glyco_transf_10 PF00852.19 CBZ31200.1 - 7.1e-16 58.4 0.0 3e-10 40.1 0.0 3.3 3 0 0 3 3 3 3 Glycosyltransferase family 10 (fucosyltransferase) C-term UAA PF08449.11 CBZ31201.1 - 3.6e-14 52.7 10.2 5.5e-11 42.2 0.3 3.4 4 0 0 4 4 4 2 UAA transporter family EamA PF00892.20 CBZ31201.1 - 5.8e-05 23.3 4.5 5.8e-05 23.3 4.5 2.5 4 0 0 4 4 4 1 EamA-like transporter family CRT-like PF08627.10 CBZ31201.1 - 0.057 12.4 1.9 0.092 11.7 1.9 1.2 1 0 0 1 1 1 0 CRT-like, chloroquine-resistance transporter-like Pkinase PF00069.25 CBZ31203.1 - 1.1e-56 192.2 0.0 1.3e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31203.1 - 7e-20 71.4 0.0 9.5e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ31203.1 - 9e-06 25.8 1.7 0.00052 20.0 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ31203.1 - 0.0031 17.1 0.1 0.0052 16.4 0.1 1.2 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 CBZ31203.1 - 0.051 13.2 0.0 2 8.0 0.0 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 RPN6_N PF18055.1 CBZ31204.1 - 9.7e-30 103.3 0.0 3.8e-29 101.4 0.0 2.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CBZ31204.1 - 2.2e-12 47.4 0.2 6.1e-12 46.0 0.2 1.8 1 0 0 1 1 1 1 PCI domain TPR_19 PF14559.6 CBZ31204.1 - 0.045 14.3 11.0 1.1 9.9 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DDRGK PF09756.9 CBZ31204.1 - 0.13 11.8 0.1 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 DDRGK domain FtsJ PF01728.19 CBZ31205.1 - 6.4e-64 215.3 0.0 8.5e-64 214.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase UQ_con PF00179.26 CBZ31206.1 - 3.7e-41 140.1 0.0 4.3e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBZ31206.1 - 0.00039 20.1 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B NUDIX_4 PF14815.6 CBZ31208.1 - 0.092 12.7 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 NUDIX domain Stevor PF17410.2 CBZ31209.1 - 0.02 14.5 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SPC25 PF06703.11 CBZ31209.1 - 0.059 13.2 0.0 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Rhomboid PF01694.22 CBZ31210.1 - 3.2e-06 27.2 14.6 0.00083 19.4 4.4 2.9 2 2 0 2 2 2 2 Rhomboid family Glyco_hydro_20b PF02838.15 CBZ31212.1 - 0.076 13.8 0.1 0.19 12.5 0.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Porin_3 PF01459.22 CBZ31213.1 - 2.8e-05 23.7 0.0 7.7e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic porin SLX9 PF15341.6 CBZ31215.1 - 0.0016 18.8 6.4 0.008 16.6 6.4 2.3 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 Aldedh PF00171.22 CBZ31215.1 - 0.077 11.5 1.2 0.098 11.1 1.2 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family MCLC PF05934.11 CBZ31215.1 - 0.52 9.0 2.0 0.74 8.5 2.0 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) RFX5_DNA_bdg PF14621.6 CBZ31216.1 - 0.071 12.9 5.3 0.19 11.4 1.8 2.5 2 0 0 2 2 2 0 RFX5 DNA-binding domain Gly_kinase PF02595.15 CBZ31217.1 - 2.2e-38 132.2 13.7 8.6e-20 71.0 0.4 6.3 5 2 1 6 6 6 5 Glycerate kinase family FGE-sulfatase PF03781.16 CBZ31218.1 - 0.063 12.8 0.9 0.1 12.1 0.9 1.5 1 1 0 1 1 1 0 Sulfatase-modifying factor enzyme 1 GIT_CC PF16559.5 CBZ31220.1 - 0.78 9.6 8.7 0.45 10.4 6.4 1.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Kinocilin PF15033.6 CBZ31221.1 - 0.078 12.6 0.6 2.4 7.8 0.6 2.3 2 0 0 2 2 2 0 Kinocilin protein Calici_PP_N PF08405.11 CBZ31221.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal HemY_N PF07219.13 CBZ31221.1 - 8.2 6.7 7.0 1.8 8.8 0.2 2.6 2 0 0 2 2 2 0 HemY protein N-terminus DUF1010 PF06231.11 CBZ31223.1 - 0.088 13.3 1.5 0.93 10.1 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1010) Pkinase PF00069.25 CBZ31224.1 - 2.3e-57 194.4 0.0 1.1e-51 175.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31224.1 - 1.2e-36 126.4 0.0 1.3e-31 109.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ31224.1 - 0.00013 21.3 0.0 0.00076 18.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CBZ31224.1 - 0.00049 19.7 0.2 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CBZ31224.1 - 0.00073 19.5 2.3 0.0027 17.7 0.2 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Sre PF03125.18 CBZ31224.1 - 0.024 13.8 0.6 0.037 13.2 0.6 1.1 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Kdo PF06293.14 CBZ31224.1 - 0.056 12.8 0.1 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3007 PF11460.8 CBZ31224.1 - 0.062 13.6 0.9 0.14 12.5 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) Pkinase_fungal PF17667.1 CBZ31224.1 - 0.073 11.8 0.8 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase MFS_1_like PF12832.7 CBZ31224.1 - 1.1 8.1 5.4 1.5 7.6 5.4 1.1 1 0 0 1 1 1 0 MFS_1 like family ASH PF15780.5 CBZ31225.1 - 9.8e-08 32.1 1.2 0.11 12.7 0.0 6.3 5 0 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Snf7 PF03357.21 CBZ31225.1 - 0.021 14.5 4.8 0.039 13.6 4.8 1.3 1 0 0 1 1 1 0 Snf7 TPR_2 PF07719.17 CBZ31226.1 - 4.4e-09 35.8 5.1 2.2e-06 27.4 2.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ31226.1 - 6e-09 35.3 4.0 1.7e-07 30.7 1.6 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ31226.1 - 5.4e-08 32.4 1.4 2.9e-05 23.6 0.2 2.7 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 CBZ31226.1 - 5e-05 23.2 2.0 0.00011 22.1 0.5 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ31226.1 - 0.03 15.1 0.3 0.03 15.1 0.3 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ31226.1 - 0.04 13.9 5.0 0.72 10.0 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ31226.1 - 0.045 13.8 1.1 0.17 12.0 0.2 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 CBZ31226.1 - 0.15 12.6 4.0 2.2 8.8 0.3 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ31226.1 - 3.8 7.7 12.7 0.1 12.8 3.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ31226.1 - 5.8 7.8 8.0 1 10.1 1.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Secretin_N_2 PF07655.13 CBZ31226.1 - 6.1 7.5 8.5 0.19 12.3 1.4 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain ATG16 PF08614.11 CBZ31226.1 - 7.8 6.7 11.4 3.6 7.8 7.8 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ARPC4 PF05856.12 CBZ31227.1 - 1.5e-49 167.8 0.0 1.7e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) SKA2 PF16740.5 CBZ31228.1 - 0.00047 19.9 5.5 0.00047 19.9 5.5 2.5 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 TACC_C PF05010.14 CBZ31228.1 - 0.042 13.6 22.6 0.055 13.3 22.6 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Sec34 PF04136.15 CBZ31228.1 - 0.095 12.6 0.4 0.095 12.6 0.4 2.7 1 1 1 2 2 2 0 Sec34-like family DUF3584 PF12128.8 CBZ31228.1 - 0.37 8.2 21.2 0.49 7.8 21.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Jnk-SapK_ap_N PF09744.9 CBZ31228.1 - 1 9.6 29.3 0.12 12.6 8.2 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Mu-like_Pro PF10123.9 CBZ31228.1 - 1.3 8.5 14.3 2.6 7.5 14.1 1.6 1 1 0 1 1 1 0 Mu-like prophage I protein ACCA PF03255.14 CBZ31228.1 - 3.4 7.5 13.5 3 7.7 1.2 2.6 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Prominin PF05478.11 CBZ31228.1 - 6 4.7 12.0 19 3.0 11.5 1.7 1 1 1 2 2 2 0 Prominin Spc7 PF08317.11 CBZ31228.1 - 6.5 5.5 24.2 0.27 10.1 4.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein zf-C4H2 PF10146.9 CBZ31228.1 - 7.3 6.8 16.4 23 5.2 16.3 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein TMF_TATA_bd PF12325.8 CBZ31228.1 - 9.3 6.5 25.8 0.76 10.0 1.4 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding WD40 PF00400.32 CBZ31229.1 - 0.02 15.8 3.8 0.64 11.0 0.1 4.3 5 1 0 5 5 5 0 WD domain, G-beta repeat Aldedh PF00171.22 CBZ31230.1 - 0.00025 19.7 0.7 0.034 12.7 0.0 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family LRR_4 PF12799.7 CBZ31231.1 - 5.4e-11 42.5 0.0 0.39 11.2 0.0 8.2 7 1 2 9 9 9 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ31231.1 - 0.34 11.1 15.6 34 4.9 0.1 7.7 10 0 0 10 10 10 0 Leucine Rich repeat Mito_fiss_reg PF05308.11 CBZ31232.1 - 4.4 7.3 6.4 1 9.4 2.1 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator Nop14 PF04147.12 CBZ31233.1 - 2.2e-44 152.0 24.8 2.6e-33 115.3 4.1 3.1 2 1 1 3 3 3 3 Nop14-like family Mito_carr PF00153.27 CBZ31234.1 - 2.4e-27 94.7 4.0 2.9e-14 52.7 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIE_alpha PF02002.17 CBZ31235.1 - 0.14 12.0 0.1 0.24 11.3 0.1 1.4 1 1 0 1 1 1 0 TFIIE alpha subunit Macoilin PF09726.9 CBZ31236.1 - 0.021 13.4 2.8 0.028 13.0 2.8 1.1 1 0 0 1 1 1 0 Macoilin family HR1 PF02185.16 CBZ31236.1 - 0.92 9.7 9.3 0.58 10.3 4.0 3.3 3 1 0 3 3 3 0 Hr1 repeat BST2 PF16716.5 CBZ31236.1 - 9.3 6.9 15.2 6.9 7.3 8.8 3.1 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Seryl_tRNA_N PF02403.22 CBZ31237.1 - 0.011 16.0 1.5 0.011 16.0 1.5 8.3 4 4 3 8 8 8 0 Seryl-tRNA synthetase N-terminal domain SpoU_sub_bind PF08032.12 CBZ31237.1 - 0.018 15.3 0.8 0.018 15.3 0.8 4.2 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding AAA_2 PF07724.14 CBZ31238.1 - 1.3e-51 175.1 0.0 4.4e-49 166.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CBZ31238.1 - 8.6e-33 112.4 3.7 8.6e-33 112.4 3.7 2.4 1 1 1 2 2 2 1 AAA lid domain AAA PF00004.29 CBZ31238.1 - 4.1e-24 85.5 0.3 1.3e-13 51.5 0.0 3.7 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CBZ31238.1 - 1.6e-22 79.3 0.2 6.5e-22 77.4 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CBZ31238.1 - 4.8e-18 65.5 0.3 5.1e-11 42.7 0.0 4.0 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ31238.1 - 5.6e-10 39.9 6.2 0.0001 22.8 0.2 4.4 3 3 0 4 4 2 2 AAA ATPase domain AAA_22 PF13401.6 CBZ31238.1 - 4.8e-08 33.4 6.7 0.0049 17.1 0.0 5.3 4 3 0 4 4 4 2 AAA domain AAA_7 PF12775.7 CBZ31238.1 - 1e-06 28.4 0.0 0.0059 16.1 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 CBZ31238.1 - 2.3e-05 23.9 0.0 0.98 8.8 0.0 3.7 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CBZ31238.1 - 4.7e-05 23.9 1.4 0.08 13.5 0.0 3.5 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CBZ31238.1 - 4.8e-05 23.2 0.0 0.068 12.9 0.0 2.9 2 0 0 2 2 2 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CBZ31238.1 - 5.3e-05 23.6 0.0 0.84 10.0 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Sigma54_activat PF00158.26 CBZ31238.1 - 0.00016 21.5 0.0 0.11 12.2 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CBZ31238.1 - 0.0004 20.4 0.1 0.52 10.4 0.0 3.4 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 CBZ31238.1 - 0.00047 19.9 0.1 2 8.2 0.0 3.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CBZ31238.1 - 0.00057 19.8 0.0 0.06 13.3 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 CBZ31238.1 - 0.00064 19.6 0.0 0.52 10.2 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CBZ31238.1 - 0.00085 19.1 2.6 1.8 8.3 0.0 3.8 3 1 0 3 3 3 1 DNA polymerase III, delta subunit Roc PF08477.13 CBZ31238.1 - 0.002 18.3 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 CBZ31238.1 - 0.003 17.9 0.3 0.33 11.3 0.1 3.2 2 2 1 3 3 3 1 AAA domain TIP49 PF06068.13 CBZ31238.1 - 0.005 16.1 0.1 1.2 8.2 0.0 2.9 2 1 0 2 2 2 1 TIP49 P-loop domain DUF815 PF05673.13 CBZ31238.1 - 0.0052 16.0 0.1 0.22 10.7 0.0 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF815) TsaE PF02367.17 CBZ31238.1 - 0.008 16.2 0.0 3.1 7.8 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 CBZ31238.1 - 0.0084 15.7 0.0 1.4 8.5 0.0 3.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain ResIII PF04851.15 CBZ31238.1 - 0.0092 16.0 1.8 5.2 7.0 0.0 3.9 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 CBZ31238.1 - 0.0095 15.9 0.1 3.7 7.4 0.0 3.0 2 1 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 CBZ31238.1 - 0.011 15.9 0.0 8.3 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBZ31238.1 - 0.012 15.3 0.0 7 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CBZ31238.1 - 0.013 15.7 0.3 3.1 8.0 0.0 3.3 4 0 0 4 4 2 0 AAA domain Ribosomal_S7 PF00177.21 CBZ31238.1 - 0.023 14.4 0.0 0.078 12.6 0.0 1.9 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e NTPase_1 PF03266.15 CBZ31238.1 - 0.023 14.6 0.1 5.3 6.9 0.0 3.1 3 0 0 3 3 3 0 NTPase ABC_tran PF00005.27 CBZ31238.1 - 0.025 15.1 1.4 9.8 6.7 0.0 3.5 3 1 0 3 3 3 0 ABC transporter AAA_6 PF12774.7 CBZ31238.1 - 0.031 13.2 0.1 0.23 10.4 0.0 2.5 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_29 PF13555.6 CBZ31238.1 - 0.036 13.8 0.0 11 5.9 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Torsin PF06309.11 CBZ31238.1 - 0.051 13.7 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 1 0 Torsin AAA_25 PF13481.6 CBZ31238.1 - 0.067 12.8 0.3 4.4 6.8 0.0 3.2 3 1 0 3 3 2 0 AAA domain TarH PF02203.15 CBZ31238.1 - 0.069 13.1 1.5 0.14 12.0 1.5 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue AAA_30 PF13604.6 CBZ31238.1 - 0.078 12.7 0.1 8.1 6.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain 4HB_MCP_1 PF12729.7 CBZ31238.1 - 0.12 11.9 6.9 0.28 10.7 6.9 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction ATP_bind_1 PF03029.17 CBZ31238.1 - 0.17 11.6 0.8 5 6.8 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 CBZ31238.1 - 1.8 9.0 6.4 7.7 6.9 0.0 4.0 3 1 1 4 4 3 0 AAA domain GrpE PF01025.19 CBZ31238.1 - 2.5 7.7 10.2 1.4 8.6 7.4 2.0 2 0 0 2 2 1 0 GrpE AAA_23 PF13476.6 CBZ31238.1 - 3.5 8.1 19.9 19 5.7 0.0 3.3 2 1 0 2 2 1 0 AAA domain UPF0449 PF15136.6 CBZ31238.1 - 4.3 7.9 7.2 8.5 6.9 5.7 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 adh_short_C2 PF13561.6 CBZ31240.1 - 0.0007 19.2 0.0 0.00089 18.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase EIAV_Rev PF11129.8 CBZ31240.1 - 0.028 14.6 0.1 0.071 13.3 0.0 1.7 2 0 0 2 2 2 0 Rev protein of equine infectious anaemia virus Peptidase_M3 PF01432.20 CBZ31241.1 - 3.4e-137 458.4 0.0 5.5e-137 457.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 LRR_4 PF12799.7 CBZ31242.1 - 9.9e-64 210.2 0.0 0.0023 18.3 0.0 16.1 10 1 4 18 18 18 16 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ31242.1 - 5.1e-10 39.0 10.3 0.69 9.7 0.2 10.9 8 3 3 12 12 12 2 Leucine rich repeat LRR_5 PF13306.6 CBZ31242.1 - 5.3e-05 23.2 0.2 1.9 8.5 0.0 5.4 4 2 0 5 5 5 1 BspA type Leucine rich repeat region (6 copies) C1_2 PF03107.16 CBZ31242.1 - 0.027 14.8 6.8 0.068 13.5 6.8 1.7 1 0 0 1 1 1 0 C1 domain Chorein_N PF12624.7 CBZ31242.1 - 0.084 13.0 0.8 92 3.2 0.0 4.6 5 1 0 5 5 5 0 N-terminal region of Chorein or VPS13 HrpB1_HrpK PF09613.10 CBZ31242.1 - 0.26 10.9 1.5 1.7 8.3 0.1 3.0 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) LRR_1 PF00560.33 CBZ31242.1 - 2.6 8.9 20.6 1.3e+02 3.8 0.0 11.2 15 0 0 15 15 15 0 Leucine Rich Repeat zf-RING_2 PF13639.6 CBZ31242.1 - 4.8 7.6 19.1 19 5.7 19.1 2.2 1 0 0 1 1 1 0 Ring finger domain Raco_middle PF17651.1 CBZ31243.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 RACo middle region 2-Hacid_dh_C PF02826.19 CBZ31244.1 - 1.2e-54 184.4 0.0 1.8e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CBZ31244.1 - 6.3e-35 119.8 0.1 8.1e-35 119.4 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CBZ31244.1 - 2.1e-05 24.8 0.3 7.1e-05 23.0 0.3 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 CBZ31244.1 - 0.0045 17.5 0.0 0.0097 16.4 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 CBZ31244.1 - 0.0071 16.4 0.5 0.013 15.6 0.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 CBZ31244.1 - 0.018 14.6 0.1 0.036 13.6 0.1 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Aminotran_5 PF00266.19 CBZ31245.1 - 4.2e-20 72.0 0.0 5e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Met_10 PF02475.16 CBZ31246.1 - 9.6e-42 143.0 0.0 1.3e-38 132.7 0.0 2.1 2 0 0 2 2 2 2 Met-10+ like-protein Methyltransf_15 PF09445.10 CBZ31246.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CBZ31246.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CBZ31246.1 - 0.011 16.5 0.0 0.038 14.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CBZ31246.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CBZ31246.1 - 0.051 13.4 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DNA_methylase PF00145.17 CBZ31246.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase MyTH4 PF00784.17 CBZ31247.1 - 0.0092 16.5 0.0 0.041 14.4 0.0 2.1 1 0 0 1 1 1 1 MyTH4 domain Acyltransferase PF01553.21 CBZ31248.1 - 1e-11 44.6 0.0 4.5e-11 42.5 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase ATP-synt_D PF01813.17 CBZ31248.1 - 0.0029 17.5 0.2 0.0063 16.4 0.2 1.5 1 0 0 1 1 1 1 ATP synthase subunit D zf_UBZ PF18439.1 CBZ31248.1 - 0.0053 16.3 1.2 0.01 15.4 1.2 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Tmp39 PF10271.9 CBZ31248.1 - 0.033 13.2 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein PrgI PF12666.7 CBZ31248.1 - 1.3 9.8 5.3 6.2 7.6 0.1 2.6 2 0 0 2 2 2 0 PrgI family protein DNA_primase_lrg PF04104.14 CBZ31249.1 - 2.5e-80 269.7 0.0 3.7e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CtaG_Cox11 PF04442.14 CBZ31250.1 - 3.4e-43 147.3 0.0 3.9e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 RNase_H2-Ydr279 PF09468.10 CBZ31251.1 - 0.018 15.2 0.2 0.038 14.2 0.2 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain CH PF00307.31 CBZ31251.1 - 0.035 14.3 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Calponin homology (CH) domain LRR_8 PF13855.6 CBZ31252.1 - 1.6e-10 40.6 15.5 5.3e-05 22.9 2.3 3.9 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CBZ31252.1 - 7.6e-10 38.9 14.4 0.0016 18.8 1.3 4.4 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ31252.1 - 2.4e-07 30.4 4.2 1.5e-05 24.5 0.7 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CBZ31252.1 - 0.012 15.6 8.3 1.3 9.3 0.1 4.8 4 1 1 5 5 5 0 Leucine Rich repeat DUF4530 PF15039.6 CBZ31252.1 - 0.073 13.2 2.8 0.36 11.0 2.8 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) FmiP_Thoc5 PF09766.9 CBZ31252.1 - 0.094 12.0 5.5 0.16 11.2 5.5 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 TACC_C PF05010.14 CBZ31252.1 - 0.16 11.7 7.5 0.28 10.9 7.5 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Tup_N PF08581.10 CBZ31252.1 - 0.27 11.5 7.2 4.4 7.7 0.6 2.8 2 0 0 2 2 2 0 Tup N-terminal Spc7 PF08317.11 CBZ31252.1 - 0.38 9.6 11.8 0.62 8.9 11.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 CBZ31252.1 - 0.51 10.6 11.8 1.1 9.5 11.8 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FAM76 PF16046.5 CBZ31252.1 - 0.86 8.9 5.3 8 5.7 3.9 2.4 2 1 0 2 2 2 0 FAM76 protein CR6_interact PF10147.9 CBZ31252.1 - 1.1 8.9 7.3 0.77 9.4 5.3 1.7 1 1 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 YabA PF06156.13 CBZ31252.1 - 2 9.1 4.9 5.1 7.8 4.2 2.0 1 1 1 2 2 2 0 Initiation control protein YabA Acetyltransf_1 PF00583.25 CBZ31253.1 - 1.7e-08 34.7 0.0 2.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBZ31253.1 - 4.7e-07 29.8 0.1 6.1e-07 29.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBZ31253.1 - 6.6e-07 29.7 0.1 9.1e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBZ31253.1 - 0.0017 18.4 0.1 0.0031 17.6 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CBZ31253.1 - 0.0059 16.1 0.9 0.008 15.7 0.9 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase DUF4558 PF15104.6 CBZ31254.1 - 0.00016 21.6 1.3 0.00016 21.6 1.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4558) ABC_tran PF00005.27 CBZ31256.1 - 1.8e-46 158.1 4.1 5.3e-22 78.8 0.0 3.8 4 0 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 CBZ31256.1 - 9.2e-25 86.5 4.6 9.2e-25 86.5 4.6 3.3 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 CBZ31256.1 - 1.5e-17 64.4 8.9 0.00014 21.8 0.5 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ31256.1 - 4e-11 42.8 1.0 0.0057 16.1 0.1 4.3 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBZ31256.1 - 5.3e-08 33.4 0.2 0.018 15.4 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CBZ31256.1 - 2e-07 30.6 0.4 0.0081 15.9 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CBZ31256.1 - 3.7e-07 30.2 0.3 0.023 14.8 0.1 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ31256.1 - 1.5e-06 28.2 0.2 0.012 15.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 CBZ31256.1 - 3e-06 27.2 5.2 0.13 12.0 0.1 4.4 4 1 0 4 4 4 2 AAA ATPase domain AAA_28 PF13521.6 CBZ31256.1 - 1.7e-05 25.1 2.8 0.021 15.0 0.1 3.7 4 0 0 4 4 4 2 AAA domain NACHT PF05729.12 CBZ31256.1 - 2.9e-05 24.0 0.1 0.79 9.6 0.0 3.4 3 0 0 3 3 3 2 NACHT domain AAA_30 PF13604.6 CBZ31256.1 - 4.6e-05 23.2 0.1 0.25 11.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CBZ31256.1 - 5.3e-05 23.4 4.5 0.32 11.2 0.0 3.8 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CBZ31256.1 - 0.00011 22.8 14.7 0.027 14.9 0.0 4.4 5 0 0 5 5 4 2 AAA domain AAA_22 PF13401.6 CBZ31256.1 - 0.00036 20.8 1.6 0.25 11.6 0.1 3.4 2 2 0 2 2 2 1 AAA domain Roc PF08477.13 CBZ31256.1 - 0.00068 19.8 0.0 2.2 8.5 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 CBZ31256.1 - 0.0013 19.1 0.1 1.2 9.6 0.1 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBZ31256.1 - 0.0018 18.8 4.5 0.1 13.2 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 CBZ31256.1 - 0.0021 17.8 1.9 1.4 8.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 CBZ31256.1 - 0.0024 18.3 0.0 0.72 10.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 CBZ31256.1 - 0.0029 17.6 0.1 2.7 8.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CBZ31256.1 - 0.0033 17.0 0.1 3.4 7.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CBZ31256.1 - 0.0046 17.0 0.1 0.91 9.5 0.0 2.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 CBZ31256.1 - 0.0067 16.2 0.1 0.25 11.1 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 CBZ31256.1 - 0.0068 16.5 0.1 8.6 6.4 0.0 3.4 3 1 1 4 4 3 0 AAA domain SRP54 PF00448.22 CBZ31256.1 - 0.023 14.3 0.3 5.4 6.6 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FeoB_N PF02421.18 CBZ31256.1 - 0.028 13.9 0.1 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_7 PF12775.7 CBZ31256.1 - 0.029 13.9 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 CBZ31256.1 - 0.036 13.6 0.1 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 CBZ31256.1 - 0.051 13.0 1.9 2.1 7.8 0.0 3.3 4 0 0 4 4 3 0 ADP-ribosylation factor family NTPase_1 PF03266.15 CBZ31256.1 - 0.053 13.4 0.2 13 5.6 0.1 3.0 3 0 0 3 3 2 0 NTPase MukB PF04310.12 CBZ31256.1 - 0.063 13.1 0.1 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal Ploopntkinase3 PF18751.1 CBZ31256.1 - 0.081 12.8 0.0 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MeaB PF03308.16 CBZ31256.1 - 0.092 11.7 0.1 7 5.5 0.0 2.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CBZ31256.1 - 0.16 12.0 7.0 7.4 6.6 0.0 4.2 4 2 0 4 4 4 0 Dynamin family AAA_27 PF13514.6 CBZ31256.1 - 0.36 10.4 4.0 6 6.4 0.0 3.3 4 0 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.17 CBZ31256.1 - 0.81 9.4 4.5 21 4.8 0.2 3.4 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Septin PF00735.18 CBZ31256.1 - 1.3 8.2 6.3 2.5 7.3 0.0 2.9 4 0 0 4 4 2 0 Septin zf-C2H2_3 PF13878.6 CBZ31258.1 - 4.3e-13 48.9 0.0 1.2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO zf_CCCH_4 PF18345.1 CBZ31259.1 - 1.9e-08 34.1 6.0 0.001 19.0 1.4 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CBZ31259.1 - 7.8e-08 32.0 7.1 0.00032 20.5 0.8 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 CBZ31259.1 - 2.4e-06 27.3 0.0 3.9e-05 23.4 0.0 2.4 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 CBZ31259.1 - 0.0054 17.4 10.3 0.039 14.6 0.3 2.8 2 1 1 3 3 3 2 Torus domain Herpes_UL87 PF03043.14 CBZ31259.1 - 0.036 12.6 0.1 0.048 12.1 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL87 family zf-CCCH_4 PF18044.1 CBZ31259.1 - 0.22 11.4 11.2 0.13 12.1 1.5 2.7 2 1 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CBZ31259.1 - 0.59 10.7 4.4 20 5.8 0.2 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Aldedh PF00171.22 CBZ31260.1 - 9.2e-106 354.1 0.0 1.1e-105 353.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF35_N PF12172.8 CBZ31260.1 - 0.23 11.3 0.8 5.6 6.9 0.8 2.4 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pkinase PF00069.25 CBZ31261.1 - 1.4e-58 198.4 0.0 1.8e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31261.1 - 6e-29 101.1 0.0 1.1e-28 100.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ31261.1 - 0.0001 21.3 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBZ31261.1 - 0.00048 19.2 0.1 0.00093 18.2 0.1 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBZ31261.1 - 0.0012 18.8 1.8 0.73 9.7 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 CBZ31261.1 - 0.0077 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ31261.1 - 0.017 14.7 0.1 0.03 13.9 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CBZ31261.1 - 0.033 13.5 0.1 0.15 11.3 0.1 2.1 1 1 0 1 1 1 0 Kinase-like AMP-binding PF00501.28 CBZ31263.1 - 3.1e-90 302.8 0.1 4.2e-90 302.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_L38e PF01781.18 CBZ31265.1 - 2.9e-29 101.0 4.0 3.4e-29 100.7 4.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Retrotran_gag_2 PF14223.6 CBZ31266.1 - 0.22 11.2 0.4 0.41 10.3 0.4 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type FYVE PF01363.21 CBZ31267.1 - 2e-12 47.1 7.7 3.4e-12 46.3 7.7 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAS PF13851.6 CBZ31267.1 - 0.0098 15.3 1.4 0.013 14.8 1.4 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FYVE_2 PF02318.16 CBZ31267.1 - 0.024 14.8 5.6 0.06 13.6 5.6 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger MAD PF05557.13 CBZ31267.1 - 0.027 12.8 2.3 0.031 12.6 2.3 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein Uso1_p115_C PF04871.13 CBZ31267.1 - 0.16 12.3 5.2 0.31 11.4 5.2 1.4 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-B_box PF00643.24 CBZ31267.1 - 0.87 9.8 8.8 3.4 7.9 4.4 2.4 2 0 0 2 2 2 0 B-box zinc finger DivIC PF04977.15 CBZ31267.1 - 3.9 7.3 6.6 1.7 8.5 2.4 2.1 1 1 1 2 2 2 0 Septum formation initiator IBR PF01485.21 CBZ31267.1 - 4 7.7 9.5 0.8 10.0 5.8 1.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_9 PF13901.6 CBZ31268.1 - 3.6e-11 43.4 0.9 0.02 14.9 0.0 4.5 4 0 0 4 4 4 4 Putative zinc-RING and/or ribbon WD40_alt PF14077.6 CBZ31271.1 - 0.45 10.4 3.3 2.6 8.0 0.4 3.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif DDRGK PF09756.9 CBZ31273.1 - 1.9e-25 89.5 24.9 3.1e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 DDRGK domain MRP-S31 PF15433.6 CBZ31273.1 - 0.12 12.1 8.6 0.24 11.1 8.9 1.4 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Nop53 PF07767.11 CBZ31273.1 - 1 8.7 22.9 0.74 9.1 21.5 1.3 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 CBZ31273.1 - 2.8 7.7 9.0 4.2 7.1 9.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4778 PF16008.5 CBZ31273.1 - 2.9 7.9 10.0 4.2 7.3 10.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) PIEZO PF15917.5 CBZ31273.1 - 8.1 5.8 10.3 12 5.3 10.3 1.3 1 0 0 1 1 1 0 Piezo Pkinase PF00069.25 CBZ31274.1 - 3.4e-30 105.3 0.0 1.6e-22 80.1 0.0 4.0 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31274.1 - 4.7e-14 52.3 0.0 7.7e-09 35.2 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ31274.1 - 0.0033 16.8 0.0 0.0092 15.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Gpr1_Fun34_YaaH PF01184.19 CBZ31276.1 - 1.1e-31 110.1 13.0 1.5e-31 109.6 13.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 CBZ31277.1 - 6.3e-27 94.5 5.2 8.1e-27 94.2 5.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 CBZ31278.1 - 1.2e-07 31.6 0.7 1.2e-07 31.6 0.7 2.0 3 0 0 3 3 3 1 GPR1/FUN34/yaaH family DUF3228 PF11539.8 CBZ31278.1 - 0.085 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) Gpr1_Fun34_YaaH PF01184.19 CBZ31279.1 - 2.7e-50 170.9 16.2 3.4e-50 170.5 16.2 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.16 CBZ31280.1 - 7.6e-32 110.6 14.9 1.9e-19 69.8 0.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CBZ31280.1 - 9.9e-09 34.0 1.5 2.3e-06 26.2 0.0 2.9 3 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_2 PF13347.6 CBZ31280.1 - 2e-08 33.3 15.4 6.5e-05 21.7 4.8 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein TMEM65 PF10507.9 CBZ31280.1 - 0.037 14.0 0.3 9.8 6.2 0.0 3.6 3 1 0 3 3 3 0 Transmembrane protein 65 ResB PF05140.14 CBZ31280.1 - 0.072 11.8 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 ResB-like family DUF4149 PF13664.6 CBZ31280.1 - 0.82 10.0 14.0 0.067 13.5 1.2 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) DUF4131 PF13567.6 CBZ31280.1 - 1 9.0 0.0 1 9.0 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) AGP PF06376.12 CBZ31281.1 - 0.11 12.4 1.5 0.39 10.6 1.5 2.0 1 0 0 1 1 1 0 Arabinogalactan peptide Ribosomal_60s PF00428.19 CBZ31283.1 - 2.2e-21 76.2 11.1 2.7e-21 76.0 11.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TLD PF07534.16 CBZ31284.1 - 1.1e-16 61.4 0.0 3.3e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 TLD Ank_2 PF12796.7 CBZ31287.1 - 1.6e-38 131.1 0.0 1.3e-13 51.4 0.0 4.4 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ31287.1 - 1.3e-25 86.6 0.2 0.00034 20.8 0.0 7.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 CBZ31287.1 - 1.3e-25 89.4 2.3 5.1e-08 33.3 0.1 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ31287.1 - 4.9e-25 87.3 3.5 7e-10 39.0 0.0 5.9 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 CBZ31287.1 - 8e-21 73.5 4.0 7.7e-06 26.1 0.1 6.4 7 0 0 7 7 7 4 Ankyrin repeat DHHC PF01529.20 CBZ31287.1 - 4.4e-07 30.1 0.3 9.5e-06 25.7 0.0 2.8 3 0 0 3 3 3 1 DHHC palmitoyltransferase SUIM_assoc PF16619.5 CBZ31288.1 - 1.7 8.8 9.8 5.1 7.2 9.8 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PHO4 PF01384.20 CBZ31289.1 - 1.5e-105 353.0 18.6 2.2e-105 352.5 18.6 1.2 1 0 0 1 1 1 1 Phosphate transporter family DSPc PF00782.20 CBZ31290.1 - 0.073 12.9 0.4 0.16 11.8 0.4 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RRM_1 PF00076.22 CBZ31291.1 - 3e-13 49.4 0.8 7.8e-05 22.4 0.0 5.3 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP130_C PF16014.5 CBZ31291.1 - 0.069 12.2 1.0 0.12 11.4 1.0 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus TruD PF01142.18 CBZ31292.1 - 0.00052 19.0 0.0 0.00094 18.1 0.0 1.3 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) CobU PF02283.16 CBZ31292.1 - 0.058 13.0 2.0 0.17 11.4 0.0 2.3 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA PF00004.29 CBZ31293.1 - 7.3e-45 152.6 0.0 1.4e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ31293.1 - 4.9e-13 48.7 1.4 7.2e-13 48.1 0.1 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 CBZ31293.1 - 1.1e-07 32.2 0.0 2.7e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 CBZ31293.1 - 3.6e-07 30.0 0.2 8.5e-07 28.8 0.2 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CBZ31293.1 - 8.1e-07 29.6 0.0 0.0015 18.9 0.0 2.5 1 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CBZ31293.1 - 8.9e-07 29.0 0.2 9.1e-06 25.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBZ31293.1 - 5.4e-06 26.2 0.0 1.5e-05 24.8 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBZ31293.1 - 5.2e-05 23.5 0.1 0.024 14.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CBZ31293.1 - 0.00025 20.3 0.0 0.00059 19.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 CBZ31293.1 - 0.00095 18.5 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 CBZ31293.1 - 0.0017 18.7 0.0 0.0053 17.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 CBZ31293.1 - 0.002 17.6 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CBZ31293.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBZ31293.1 - 0.0035 16.9 0.0 0.0098 15.4 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 CBZ31293.1 - 0.0038 17.0 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CBZ31293.1 - 0.0039 17.2 0.0 0.0085 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ31293.1 - 0.0049 17.4 0.1 0.018 15.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain Parvo_NS1 PF01057.17 CBZ31293.1 - 0.0055 15.8 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CBZ31293.1 - 0.0085 15.7 0.0 0.067 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CBZ31293.1 - 0.015 15.8 0.1 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 CBZ31293.1 - 0.017 14.5 2.2 0.19 11.1 0.0 2.7 2 1 1 3 3 3 0 KaiC Sigma54_activat PF00158.26 CBZ31293.1 - 0.019 14.7 0.1 0.084 12.6 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 CBZ31293.1 - 0.023 14.6 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CBZ31293.1 - 0.031 14.5 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBZ31293.1 - 0.031 14.2 0.9 1.1 9.2 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea PhoH PF02562.16 CBZ31293.1 - 0.034 13.6 0.1 0.079 12.4 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein Prot_ATP_OB_N PF17758.1 CBZ31293.1 - 0.036 13.7 0.0 0.097 12.3 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 CBZ31293.1 - 0.044 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CBZ31293.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ31293.1 - 0.072 13.0 0.1 0.28 11.1 0.0 2.0 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.6 CBZ31293.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CBZ31293.1 - 0.12 12.7 0.2 0.4 11.0 0.1 1.7 1 1 1 2 2 2 0 AAA domain Myb_Cef PF11831.8 CBZ31294.1 - 0.91 9.0 8.4 2.1 7.9 8.4 1.5 1 0 0 1 1 1 0 pre-mRNA splicing factor component TSGP1 PF07771.11 CBZ31294.1 - 2.7 8.2 5.0 9.3 6.4 5.0 1.9 1 0 0 1 1 1 0 Tick salivary peptide group 1 ABC2_membrane_2 PF12679.7 CBZ31294.1 - 3.7 6.8 9.3 3.4 6.9 5.1 2.6 2 0 0 2 2 2 0 ABC-2 family transporter protein EphA2_TM PF14575.6 CBZ31294.1 - 4.4 8.2 0.0 4.4 8.2 0.0 3.8 5 0 0 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain NARP1 PF12569.8 CBZ31294.1 - 9.9 4.9 6.4 17 4.2 6.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Nucleo_P87 PF07267.11 CBZ31295.1 - 0.12 11.2 0.3 0.2 10.4 0.3 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ADH_zinc_N PF00107.26 CBZ31296.1 - 5.7e-20 71.6 0.1 1e-19 70.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBZ31296.1 - 5.7e-20 72.7 0.0 1.1e-19 71.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ31296.1 - 2.4e-09 37.0 0.1 7e-09 35.5 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain RNA_polI_A34 PF08208.11 CBZ31297.1 - 0.48 10.5 9.7 0.64 10.1 9.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 UPF0239 PF06783.11 CBZ31297.1 - 2.8 8.2 5.6 4.5 7.5 5.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Helicase_C_2 PF13307.6 CBZ31298.1 - 3.2e-41 141.3 0.0 1.1e-40 139.5 0.0 1.9 1 1 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBZ31298.1 - 2.3e-20 72.9 0.0 2.7e-07 30.4 0.0 4.3 4 0 0 4 4 4 4 DEAD_2 Methyltransf_31 PF13847.6 CBZ31299.1 - 5e-08 32.9 0.0 6.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ31299.1 - 2.1e-07 31.5 0.1 7.9e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ31299.1 - 0.00019 22.0 0.0 0.00069 20.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CBZ31299.1 - 0.0019 17.7 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CBZ31299.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 CBZ31299.1 - 0.0067 15.4 0.1 0.014 14.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 CBZ31299.1 - 0.0068 17.1 0.0 0.015 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CBZ31299.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MeaB PF03308.16 CBZ31300.1 - 1e-73 247.6 0.1 1.3e-73 247.2 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CBZ31300.1 - 1.3e-07 31.4 0.0 3.6e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CBZ31300.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 CBZ31300.1 - 0.0053 16.3 0.0 0.37 10.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SMC_N PF02463.19 CBZ31300.1 - 0.0062 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CBZ31300.1 - 0.0091 16.3 0.2 0.91 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ31300.1 - 0.0099 16.3 0.1 0.023 15.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain ParA PF10609.9 CBZ31300.1 - 0.012 15.1 0.5 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase Gly-rich_Ago1 PF12764.7 CBZ31302.1 - 2.8 8.8 7.2 0.5 11.2 3.6 1.6 2 0 0 2 2 2 0 Glycine-rich region of argonaut EamA PF00892.20 CBZ31304.1 - 0.00043 20.5 7.4 0.00043 20.5 7.4 3.9 4 0 0 4 4 4 1 EamA-like transporter family Zip PF02535.22 CBZ31304.1 - 0.00066 19.0 1.2 0.65 9.2 0.0 2.9 3 0 0 3 3 3 2 ZIP Zinc transporter CRT-like PF08627.10 CBZ31304.1 - 0.0037 16.2 12.7 0.53 9.2 0.1 3.7 3 1 1 4 4 4 3 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 CBZ31304.1 - 0.085 12.2 4.9 0.025 13.9 1.6 1.7 2 0 0 2 2 2 0 Triose-phosphate Transporter family EIID-AGA PF03613.14 CBZ31305.1 - 0.013 14.7 1.4 0.037 13.2 1.3 1.8 1 1 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component CRT-like PF08627.10 CBZ31305.1 - 0.37 9.7 12.8 0.041 12.8 4.9 2.4 2 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like AAA_16 PF13191.6 CBZ31306.1 - 0.0006 20.2 0.5 0.0022 18.4 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CBZ31306.1 - 0.0098 15.9 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CBZ31306.1 - 0.038 13.4 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein HEM4 PF02602.15 CBZ31307.1 - 2.1e-63 213.8 0.6 2.4e-63 213.6 0.6 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DEAD PF00270.29 CBZ31308.1 - 7.5e-20 71.4 0.0 1e-18 67.7 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.15 CBZ31308.1 - 4.8e-09 36.4 0.0 1.4e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ31308.1 - 0.00015 22.1 0.1 0.00042 20.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Nop53 PF07767.11 CBZ31308.1 - 8.1 5.7 19.7 0.11 11.9 8.2 2.2 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Beta_helix PF13229.6 CBZ31309.1 - 0.023 14.5 0.9 7.3 6.4 0.0 4.9 7 1 0 7 7 7 0 Right handed beta helix region tRNA_edit PF04073.15 CBZ31310.1 - 1.1e-18 67.5 0.0 4.1e-18 65.6 0.0 1.8 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Mqo PF06039.15 CBZ31312.1 - 0.23 9.9 0.0 0.35 9.4 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) COX17 PF05051.13 CBZ31313.1 - 3.5e-15 56.1 7.3 4.8e-15 55.6 7.3 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Rbsn PF11464.8 CBZ31313.1 - 0.035 13.8 0.3 8.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Rabenosyn Rab binding domain TatD_DNase PF01026.21 CBZ31314.1 - 2.4e-60 204.1 0.0 3.5e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 CBZ31314.1 - 0.058 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Amidohydrolase LRR_4 PF12799.7 CBZ31316.1 - 2e-12 47.1 3.2 7.7e-05 23.0 0.0 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.6 CBZ31316.1 - 2.6e-09 37.4 0.0 5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_9 PF14580.6 CBZ31316.1 - 2.6e-09 36.8 1.6 0.016 14.7 0.6 3.6 3 1 0 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 CBZ31316.1 - 1.4e-07 31.1 6.1 0.0086 15.8 0.5 4.2 3 1 0 3 3 3 3 Leucine rich repeat ubiquitin PF00240.23 CBZ31316.1 - 0.00058 19.6 0.1 0.01 15.6 0.1 2.4 1 1 0 1 1 1 1 Ubiquitin family LRR_6 PF13516.6 CBZ31316.1 - 0.08 13.0 12.8 2.1 8.6 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ31316.1 - 0.15 12.7 1.7 56 4.9 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Pkinase PF00069.25 CBZ31317.1 - 1.5e-52 178.5 0.1 3.6e-29 101.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31317.1 - 7.8e-23 81.1 0.0 5.1e-08 32.5 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ31317.1 - 0.0024 16.7 0.0 0.0071 15.2 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ31317.1 - 0.021 14.2 0.0 0.069 12.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like GHMP_kinases_C PF08544.13 CBZ31317.1 - 0.024 15.0 1.2 2.7 8.4 0.1 3.1 2 0 0 2 2 2 0 GHMP kinases C terminal Pkinase PF00069.25 CBZ31318.1 - 1.5e-52 178.5 0.1 3.6e-29 101.9 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31318.1 - 7.8e-23 81.1 0.0 5.1e-08 32.5 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ31318.1 - 0.0024 16.7 0.0 0.0071 15.2 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ31318.1 - 0.021 14.2 0.0 0.069 12.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like GHMP_kinases_C PF08544.13 CBZ31318.1 - 0.024 15.0 1.2 2.7 8.4 0.1 3.1 2 0 0 2 2 2 0 GHMP kinases C terminal RNA_pol_Rpb4 PF03874.16 CBZ31319.1 - 0.024 15.0 0.0 0.37 11.1 0.0 2.4 3 0 0 3 3 3 0 RNA polymerase Rpb4 6PF2K PF01591.18 CBZ31320.1 - 4.7e-64 215.7 0.0 6.8e-64 215.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Ank_2 PF12796.7 CBZ31320.1 - 2.5e-13 50.4 0.1 6.7e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ31320.1 - 8.1e-11 42.2 0.9 2.8e-08 34.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ31320.1 - 1.8e-10 40.8 3.8 2.3e-09 37.3 0.4 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ31320.1 - 3.4e-08 33.6 0.8 2e-05 24.8 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CBZ31320.1 - 1.7e-06 27.9 0.1 0.021 15.3 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat AAA_33 PF13671.6 CBZ31320.1 - 2.8e-06 27.6 0.1 1.4e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain His_Phos_1 PF00300.22 CBZ31320.1 - 0.00087 19.0 0.0 0.4 10.3 0.0 3.1 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) Phage_base_V PF04717.12 CBZ31321.1 - 0.088 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 Type VI secretion system, phage-baseplate injector CDP-OH_P_transf PF01066.21 CBZ31323.1 - 5.8e-17 62.2 0.0 1.2e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase zf-C6H2 PF15801.5 CBZ31325.1 - 5.3e-08 33.1 11.9 1.5e-07 31.6 11.9 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CBZ31325.1 - 0.22 11.6 9.6 0.56 10.3 9.6 1.7 1 0 0 1 1 1 0 MYND finger LRR_8 PF13855.6 CBZ31328.1 - 8.1e-09 35.1 11.5 4.8e-05 23.0 1.1 2.7 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBZ31328.1 - 1.1e-08 35.3 9.4 0.015 15.7 0.0 4.2 1 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ31328.1 - 1 9.6 9.3 48 4.4 0.2 4.7 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ31328.1 - 4.1 8.3 9.3 1.4e+02 3.6 0.0 4.8 4 1 0 4 4 4 0 Leucine Rich Repeat DHHA1 PF02272.19 CBZ31329.1 - 0.022 15.2 4.8 0.024 15.1 2.5 2.3 2 0 0 2 2 2 0 DHHA1 domain NIF PF03031.18 CBZ31330.1 - 8.3e-27 93.9 0.0 1e-18 67.6 0.0 2.6 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase Brix PF04427.18 CBZ31331.1 - 1.6e-33 116.5 0.1 2.1e-33 116.0 0.1 1.2 1 0 0 1 1 1 1 Brix domain Pyrophosphatase PF00719.19 CBZ31332.1 - 2.3e-43 147.7 0.0 2.8e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Got1 PF04178.12 CBZ31333.1 - 8.7e-30 103.5 20.9 1.4e-29 102.8 20.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family SdpI PF13630.6 CBZ31333.1 - 0.14 12.3 12.1 1.6 8.9 2.3 2.5 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF202 PF02656.15 CBZ31333.1 - 0.32 11.5 2.5 3.3 8.2 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) IBV_3C PF03620.13 CBZ31333.1 - 2.2 8.8 7.1 0.77 10.3 4.2 1.8 1 1 0 2 2 2 0 IBV 3C protein Amidohydro_3 PF07969.11 CBZ31334.1 - 6.5e-62 210.5 8.1 1e-61 209.9 8.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CBZ31334.1 - 1.3e-14 54.3 2.6 6e-10 38.9 1.3 3.1 2 1 0 2 2 2 2 Amidohydrolase family Cu-oxidase_2 PF07731.14 CBZ31336.1 - 7.7e-20 71.0 1.1 7.7e-20 71.0 1.1 3.5 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CBZ31336.1 - 4.5e-10 39.6 6.6 8.7e-07 29.0 2.3 3.8 3 1 0 3 3 3 2 Multicopper oxidase MORN PF02493.20 CBZ31338.1 - 1e-22 78.6 43.1 1.1e-06 28.1 1.7 7.5 8 1 0 8 8 8 6 MORN repeat DUF3048_C PF17479.2 CBZ31338.1 - 0.38 11.2 4.4 0.37 11.2 0.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain EIF_2_alpha PF07541.12 CBZ31339.1 - 3.8e-17 62.4 0.0 2.7e-15 56.5 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CBZ31339.1 - 2.4e-12 47.0 0.6 5.4e-12 45.9 0.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.9 CBZ31339.1 - 0.03 14.9 0.1 0.06 14.0 0.1 1.6 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Ntox35 PF15534.6 CBZ31339.1 - 0.047 14.1 0.0 0.26 11.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial toxin 35 E1-E2_ATPase PF00122.20 CBZ31340.1 - 5.4e-48 162.9 0.7 5.4e-48 162.9 0.7 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBZ31340.1 - 5.8e-44 150.0 6.0 5.8e-44 150.0 6.0 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CBZ31340.1 - 2.4e-21 77.0 0.1 1.8e-20 74.1 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ31340.1 - 3.8e-17 62.1 0.0 1e-16 60.8 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBZ31340.1 - 1.6e-12 46.9 0.0 4.3e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBZ31340.1 - 1.6e-07 31.4 1.2 4.5e-06 26.6 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ31340.1 - 0.014 15.8 0.0 0.042 14.3 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase PDEase_I PF00233.19 CBZ31341.1 - 6.5e-20 71.9 0.0 1e-19 71.2 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase zf-C2H2_2 PF12756.7 CBZ31345.1 - 4.5 7.7 9.3 0.051 13.9 1.3 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Topo_C_assoc PF14370.6 CBZ31346.1 - 5e-28 96.8 0.3 7.2e-28 96.3 0.3 1.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4171 PF13775.6 CBZ31346.1 - 0.0082 16.6 9.6 0.014 15.9 9.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4171) SPX PF03105.19 CBZ31346.1 - 0.033 14.1 3.7 0.034 14.1 3.7 1.2 1 0 0 1 1 1 0 SPX domain DUF4614 PF15391.6 CBZ31346.1 - 0.082 12.9 8.1 0.14 12.2 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Miga PF10265.9 CBZ31346.1 - 0.11 11.5 1.4 0.12 11.3 1.4 1.1 1 0 0 1 1 1 0 Mitoguardin RAP1 PF07218.11 CBZ31346.1 - 0.2 9.9 12.9 0.26 9.5 12.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 CBZ31346.1 - 0.22 10.1 4.4 0.24 9.9 4.4 1.1 1 0 0 1 1 1 0 Macoilin family MAGE_N PF12440.8 CBZ31346.1 - 5.9 7.6 0.0 5.9 7.6 0.0 3.1 3 1 1 4 4 4 0 Melanoma associated antigen family N terminal Methyltransf_25 PF13649.6 CBZ31347.1 - 0.00077 20.1 0.1 0.0022 18.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ31347.1 - 0.0056 16.5 0.0 0.0082 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain APG17 PF04108.12 CBZ31348.1 - 0.0054 15.9 0.6 0.0065 15.6 0.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 FlaC_arch PF05377.11 CBZ31348.1 - 0.016 15.6 0.4 0.034 14.5 0.4 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 CBZ31348.1 - 0.021 15.1 0.2 0.034 14.5 0.2 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_F PF12259.8 CBZ31348.1 - 0.036 12.6 0.0 0.044 12.3 0.0 1.0 1 0 0 1 1 1 0 Baculovirus F protein DASH_Dam1 PF08653.10 CBZ31348.1 - 0.051 13.4 0.1 0.085 12.7 0.1 1.3 1 0 0 1 1 1 0 DASH complex subunit Dam1 CorA PF01544.18 CBZ31348.1 - 0.06 12.6 0.3 0.071 12.4 0.3 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3584 PF12128.8 CBZ31350.1 - 0.027 12.0 9.3 0.037 11.6 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1651 PF07864.11 CBZ31350.1 - 0.085 13.2 0.0 0.59 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) eIF3_N PF09440.10 CBZ31350.1 - 0.25 11.8 6.0 0.75 10.2 0.2 2.2 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain MAD PF05557.13 CBZ31351.1 - 0.021 13.2 2.2 0.038 12.4 2.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein betaPIX_CC PF16523.5 CBZ31351.1 - 0.13 12.1 2.2 0.18 11.6 0.4 2.1 2 0 0 2 2 2 0 betaPIX coiled coil CENP-H PF05837.12 CBZ31351.1 - 0.41 11.1 5.5 0.61 10.5 3.5 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) KH_6 PF15985.5 CBZ31352.1 - 2.4e-09 37.4 0.0 1.3e-08 35.0 0.0 2.2 1 1 0 1 1 1 1 KH domain VSP PF03302.13 CBZ31356.1 - 0.034 13.0 118.9 0.0093 14.9 32.3 4.9 1 1 4 5 5 5 0 Giardia variant-specific surface protein VSP PF03302.13 CBZ31357.1 - 0.91 8.3 87.8 0.032 13.1 35.6 4.7 2 1 2 5 5 5 0 Giardia variant-specific surface protein DUF4802 PF16060.5 CBZ31358.1 - 0.013 15.6 1.5 0.033 14.3 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4802) FSA_C PF10479.9 CBZ31358.1 - 0.059 11.5 13.1 0.073 11.2 13.1 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TALPID3 PF15324.6 CBZ31358.1 - 3 5.4 10.3 3.9 5.0 10.3 1.1 1 0 0 1 1 1 0 Hedgehog signalling target VSP PF03302.13 CBZ31359.1 - 0.0011 17.9 40.5 0.018 13.9 4.3 3.9 1 1 3 4 4 4 3 Giardia variant-specific surface protein cEGF PF12662.7 CBZ31359.1 - 0.16 11.9 17.6 0.59 10.1 1.4 5.0 4 0 0 4 4 4 0 Complement Clr-like EGF-like DUF5075 PF16825.5 CBZ31360.1 - 0.0065 16.2 3.0 0.21 11.3 3.0 2.3 1 1 0 1 1 1 1 IGP family C-type lectin domain OATP PF03137.20 CBZ31360.1 - 0.064 11.5 0.0 0.1 10.8 0.0 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Toprim_4 PF13662.6 CBZ31360.1 - 0.082 13.4 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Toprim domain Orthoreo_P10 PF07204.11 CBZ31361.1 - 0.013 15.5 0.1 0.026 14.5 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 TMEM52 PF14979.6 CBZ31361.1 - 0.027 14.4 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane 52 Shisa PF13908.6 CBZ31361.1 - 0.029 14.6 0.7 0.029 14.6 0.7 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator GRAM PF02893.20 CBZ31362.1 - 8.4e-06 25.6 0.1 2.5e-05 24.1 0.0 1.9 2 1 0 2 2 2 1 GRAM domain PseudoU_synth_2 PF00849.22 CBZ31363.1 - 3.3e-41 141.0 0.0 5.8e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase TPR_2 PF07719.17 CBZ31364.1 - 4.8e-06 26.3 11.3 0.00096 19.1 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ31364.1 - 1.5e-05 24.6 8.3 0.00082 19.1 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ31364.1 - 0.0012 18.7 3.7 0.0014 18.5 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ31364.1 - 0.0018 18.2 1.1 0.11 12.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ31364.1 - 0.0029 17.9 0.3 0.0029 17.9 0.3 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ31364.1 - 0.003 18.2 17.4 0.079 13.6 0.6 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ31364.1 - 0.0096 16.0 0.1 0.028 14.5 0.1 1.8 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.6 CBZ31364.1 - 0.015 15.4 2.4 0.031 14.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4129 PF13559.6 CBZ31364.1 - 4 7.8 8.9 0.32 11.3 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4129) TPR_6 PF13174.6 CBZ31364.1 - 9.4 7.1 9.2 17 6.3 0.3 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat MRP-L47 PF06984.13 CBZ31365.1 - 5e-29 100.3 0.2 9.4e-29 99.4 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) PRIMA1 PF16101.5 CBZ31365.1 - 1.9 8.5 6.2 7 6.7 1.0 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 A_deaminase PF00962.22 CBZ31366.1 - 3.8e-92 309.1 0.2 1.1e-66 225.4 0.0 3.1 3 0 0 3 3 3 2 Adenosine/AMP deaminase T2SSM_b PF10741.9 CBZ31366.1 - 0.07 12.9 0.0 0.29 10.9 0.0 2.0 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M subtype b ADH_N PF08240.12 CBZ31367.1 - 3.9e-06 26.7 0.6 7.7e-06 25.8 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF2459 PF09601.10 CBZ31367.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) DUF4164 PF13747.6 CBZ31368.1 - 0.0017 18.6 0.9 0.0036 17.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) TRCF PF03461.15 CBZ31368.1 - 0.03 14.7 0.1 0.048 14.0 0.1 1.4 1 0 0 1 1 1 0 TRCF domain DUF4131 PF13567.6 CBZ31368.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Glyco_hydro_32N PF00251.20 CBZ31369.1 - 6e-57 193.5 9.7 7.7e-57 193.2 9.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CBZ31369.1 - 3.8e-11 43.2 0.0 7.7e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_1 PF00024.26 CBZ31369.1 - 0.00013 21.9 0.6 0.00026 20.9 0.6 1.5 1 0 0 1 1 1 1 PAN domain DUF5074 PF16819.5 CBZ31369.1 - 0.031 14.3 0.3 3.8 7.6 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5074) PAN_4 PF14295.6 CBZ31369.1 - 0.038 13.9 1.3 0.093 12.7 1.3 1.6 1 0 0 1 1 1 0 PAN domain RNB PF00773.19 CBZ31371.1 - 1.2e-52 179.3 0.0 6.1e-52 177.0 0.0 2.0 2 0 0 2 2 2 1 RNB domain Arf PF00025.21 CBZ31372.1 - 3.8e-54 182.8 0.0 4.4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CBZ31372.1 - 7.7e-15 54.9 0.0 8.9e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ31372.1 - 3.3e-14 53.1 0.0 4.4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ31372.1 - 1.2e-10 41.1 0.0 1.4e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBZ31372.1 - 5.2e-09 35.8 0.0 6.8e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CBZ31372.1 - 8.8e-09 35.0 0.4 1e-05 24.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CBZ31372.1 - 3.1e-07 30.5 0.0 4.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Urocanase_N PF17391.2 CBZ31372.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Urocanase N-terminal domain AAA_21 PF13304.6 CBZ31372.1 - 0.024 14.5 0.2 0.18 11.6 0.2 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 CBZ31372.1 - 0.039 14.5 0.0 0.096 13.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 CBZ31372.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 CBZ31372.1 - 0.096 12.1 0.0 0.35 10.2 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_15 PF13175.6 CBZ31372.1 - 0.14 11.8 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain zf-MYND PF01753.18 CBZ31373.1 - 0.0026 17.8 10.3 0.0057 16.7 10.3 1.6 1 0 0 1 1 1 1 MYND finger PhyH PF05721.13 CBZ31375.1 - 7e-42 144.1 0.0 9.2e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3243 PF11588.8 CBZ31375.1 - 0.12 12.7 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3243) Shisa PF13908.6 CBZ31376.1 - 0.00079 19.7 1.6 0.0012 19.1 0.7 1.7 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Epiglycanin_C PF14654.6 CBZ31376.1 - 0.0041 17.2 0.0 0.0093 16.0 0.0 1.6 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region EphA2_TM PF14575.6 CBZ31376.1 - 0.0094 16.8 0.0 0.024 15.5 0.0 1.8 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain FAM163 PF15069.6 CBZ31376.1 - 0.022 15.2 0.0 0.047 14.2 0.0 1.5 1 0 0 1 1 1 0 FAM163 family FixS PF03597.15 CBZ31376.1 - 0.044 13.5 0.0 0.044 13.5 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type ECSCR PF15820.5 CBZ31376.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator TMIE PF16038.5 CBZ31376.1 - 7.7 6.4 8.5 14 5.6 8.5 1.3 1 0 0 1 1 1 0 TMIE protein ANAPC10 PF03256.16 CBZ31377.1 - 1e-64 217.6 0.0 6.9e-59 198.6 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) TPR_1 PF00515.28 CBZ31379.1 - 4.6e-11 42.0 1.0 0.00013 21.7 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ31379.1 - 4.7e-08 32.5 12.6 1.2e-05 25.0 0.2 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ31379.1 - 8.7e-07 28.7 4.2 0.0023 18.0 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ31379.1 - 4.2e-06 26.4 6.7 0.0016 18.1 0.4 2.6 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 CBZ31379.1 - 8.5e-06 26.2 1.7 0.0027 18.4 0.0 5.5 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ31379.1 - 0.0042 17.4 11.4 0.12 12.7 0.2 5.0 5 1 0 5 5 5 2 Tetratricopeptide repeat SNAP PF14938.6 CBZ31379.1 - 0.007 15.8 3.3 0.04 13.3 0.3 2.6 3 0 0 3 3 3 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 CBZ31379.1 - 0.014 15.4 1.2 0.91 9.7 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ31379.1 - 0.027 15.1 3.5 0.56 11.0 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 CBZ31379.1 - 0.05 13.3 0.4 0.05 13.3 0.4 3.6 2 1 1 4 4 4 0 Tetratricopeptide repeat-like domain COMMD1_N PF17221.3 CBZ31379.1 - 0.052 13.9 0.3 3.2 8.1 0.0 2.6 2 0 0 2 2 2 0 COMMD1 N-terminal domain Spore_SspJ PF09575.10 CBZ31379.1 - 0.22 11.9 1.1 0.87 10.0 1.1 2.0 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) TPR_9 PF13371.6 CBZ31379.1 - 0.47 10.6 10.5 0.23 11.6 0.5 3.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ31379.1 - 2.4 8.7 23.5 0.4 11.2 0.7 4.8 5 1 0 5 5 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CBZ31379.1 - 8.1 6.9 8.9 4.2 7.8 0.3 3.2 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation Lectin_C PF00059.21 CBZ31380.1 - 0.12 13.1 0.0 0.33 11.7 0.0 1.8 1 0 0 1 1 1 0 Lectin C-type domain AF-4 PF05110.13 CBZ31380.1 - 3.2 5.7 5.8 5.7 4.9 5.8 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.11 CBZ31380.1 - 5.4 5.2 4.0 8.9 4.5 4.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 CBZ31381.1 - 8.8e-41 140.0 0.0 9.6e-22 77.6 0.0 4.7 4 1 0 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31381.1 - 1.2e-32 113.2 0.0 1.8e-16 60.2 0.0 4.2 4 0 0 4 4 4 4 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ31381.1 - 0.00017 20.5 0.3 0.00042 19.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBZ31381.1 - 0.076 12.9 3.0 0.53 10.2 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Peptidase_C2 PF00648.21 CBZ31382.1 - 1.9e-54 184.7 0.0 2.8e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ31382.1 - 6.1e-34 116.5 0.0 1.2e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Lyase_1 PF00206.20 CBZ31383.1 - 6.1e-49 167.1 0.0 8.3e-49 166.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 CBZ31383.1 - 5.7e-45 152.1 0.0 9.6e-45 151.4 0.0 1.4 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal Thoc2 PF11732.8 CBZ31383.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Arf PF00025.21 CBZ31385.1 - 3.7e-61 205.6 0.0 4.3e-61 205.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBZ31385.1 - 7.8e-15 55.2 0.0 1e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ31385.1 - 4.3e-14 52.4 0.0 5.2e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBZ31385.1 - 1.7e-11 44.0 0.0 2.2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBZ31385.1 - 4e-11 42.7 0.1 2.4e-08 33.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBZ31385.1 - 3.9e-06 26.4 0.0 5e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ31385.1 - 0.00013 22.0 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBZ31385.1 - 0.00041 19.7 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase NACHT PF05729.12 CBZ31385.1 - 0.012 15.5 0.1 0.11 12.4 0.1 2.0 1 1 0 1 1 1 0 NACHT domain GTP_EFTU PF00009.27 CBZ31385.1 - 0.036 13.6 0.0 0.41 10.2 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CBZ31385.1 - 0.15 12.3 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBZ31385.1 - 0.15 11.3 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ATP_bind_1 PF03029.17 CBZ31385.1 - 0.21 11.4 0.0 0.76 9.5 0.0 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein ANAPC_CDC26 PF10471.9 CBZ31386.1 - 7.9 7.4 8.2 8.4 7.3 4.4 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 NTP_transf_2 PF01909.23 CBZ31387.1 - 1.4e-06 28.5 0.0 3.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CBZ31387.1 - 0.00059 20.0 0.1 0.0013 18.9 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 CBZ31387.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Ank_2 PF12796.7 CBZ31389.1 - 2.6e-20 72.8 1.4 1.8e-09 38.0 0.0 4.6 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ31389.1 - 3.9e-19 68.7 1.5 7.5e-06 26.4 0.0 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ31389.1 - 6.2e-17 61.4 5.5 7.4e-10 38.9 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ31389.1 - 1.6e-16 58.7 4.6 0.0004 20.6 0.0 7.1 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 CBZ31389.1 - 6.3e-15 54.9 12.2 2.3e-06 27.8 0.0 6.5 7 1 0 7 7 7 3 Ankyrin repeat DHHC PF01529.20 CBZ31389.1 - 1.1e-14 54.6 1.5 1.1e-14 54.6 1.5 2.6 2 2 1 3 3 3 1 DHHC palmitoyltransferase CopD PF05425.13 CBZ31389.1 - 3.3 8.2 9.5 0.72 10.3 0.3 3.7 3 0 0 3 3 3 0 Copper resistance protein D HisKA_3 PF07730.13 CBZ31390.1 - 3.7 8.1 8.5 0.34 11.5 1.7 2.7 2 1 1 3 3 3 0 Histidine kinase EF-hand_7 PF13499.6 CBZ31391.1 - 1.9e-08 34.6 0.0 0.012 16.0 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ31391.1 - 1.4e-06 27.8 0.0 0.41 10.7 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain zf-RING_UBOX PF13445.6 CBZ31391.1 - 2.2e-05 24.4 1.9 2.2e-05 24.4 1.9 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ31391.1 - 2.3e-05 24.2 5.5 5.9e-05 22.9 5.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ31391.1 - 0.0001 22.4 6.5 0.0001 22.4 6.5 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CBZ31391.1 - 0.00011 21.9 7.6 0.0011 18.8 7.6 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ31391.1 - 0.00014 21.7 5.2 0.00038 20.4 5.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBZ31391.1 - 0.00024 20.9 6.3 0.0017 18.2 6.3 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CBZ31391.1 - 0.00077 19.3 4.9 0.00077 19.3 4.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ31391.1 - 0.00081 19.7 7.0 0.00081 19.7 7.0 2.1 2 0 0 2 2 1 1 Ring finger domain EF-hand_1 PF00036.32 CBZ31391.1 - 0.0034 16.8 0.0 2.6 7.8 0.0 3.5 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 CBZ31391.1 - 0.013 15.3 0.0 0.22 11.4 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair MAGE_N PF12440.8 CBZ31391.1 - 0.03 15.0 6.1 0.03 15.0 6.1 4.6 4 1 0 4 4 2 0 Melanoma associated antigen family N terminal zf-RING_6 PF14835.6 CBZ31391.1 - 0.047 13.6 2.6 0.13 12.1 2.6 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein EF-hand_9 PF14658.6 CBZ31391.1 - 0.11 12.9 0.0 0.56 10.6 0.0 2.2 3 0 0 3 3 2 0 EF-hand domain DnaJ_CXXCXGXG PF00684.19 CBZ31391.1 - 0.18 12.2 7.5 0.86 10.0 0.4 2.9 2 1 2 4 4 3 0 DnaJ central domain DZR PF12773.7 CBZ31391.1 - 1.8 8.7 7.4 13 5.9 7.4 2.5 1 1 0 1 1 1 0 Double zinc ribbon Elf1 PF05129.13 CBZ31391.1 - 3 8.0 6.9 3.8 7.6 3.6 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-4CXXC_R1 PF10497.9 CBZ31391.1 - 4.6 7.5 7.0 15 5.9 6.0 2.3 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 TPR_19 PF14559.6 CBZ31392.1 - 3.7e-37 126.7 63.3 5.9e-06 26.7 0.2 15.3 9 5 6 15 15 15 11 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ31392.1 - 9e-29 97.3 46.5 0.0038 17.2 0.2 19.9 21 0 0 21 21 20 6 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ31392.1 - 1.6e-26 92.7 57.1 1.1e-06 29.2 4.2 13.8 11 1 1 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ31392.1 - 8.6e-22 76.0 26.6 0.0014 18.4 0.3 13.8 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ31392.1 - 8.3e-20 69.3 17.9 0.092 13.0 0.2 13.6 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ31392.1 - 1.7e-17 62.6 90.0 0.00018 22.1 0.2 21.7 13 7 10 23 23 22 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ31392.1 - 6e-11 42.5 66.1 5e-05 23.5 0.1 14.6 11 4 3 14 14 14 6 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ31392.1 - 2.5e-10 39.6 31.4 0.61 10.3 0.0 13.1 14 0 0 14 14 12 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ31392.1 - 3.4e-08 33.3 10.2 0.82 10.2 0.0 10.6 11 1 1 12 12 10 1 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ31392.1 - 1.1e-07 31.8 47.7 0.044 14.4 0.3 14.1 14 0 0 14 14 12 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBZ31392.1 - 2.5e-05 23.9 28.1 0.17 11.6 1.0 8.2 8 2 1 9 9 9 3 Bacterial type III secretion protein (HrpB1_HrpK) NARP1 PF12569.8 CBZ31392.1 - 8.1e-05 21.7 2.8 0.83 8.5 0.1 5.0 4 1 1 5 5 5 2 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 CBZ31392.1 - 9.9e-05 22.5 31.3 1 9.6 0.1 10.3 6 2 3 10 10 10 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 CBZ31392.1 - 0.00016 21.4 2.7 0.38 10.4 0.0 4.8 4 0 0 4 4 4 1 26S proteasome subunit RPN7 TPR_6 PF13174.6 CBZ31392.1 - 0.00054 20.4 73.1 0.8 10.5 0.0 19.8 23 0 0 23 23 21 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ31392.1 - 0.0021 17.7 33.3 1.4 8.7 0.2 12.0 15 1 1 16 16 14 1 TPR repeat PPR PF01535.20 CBZ31392.1 - 0.012 15.8 2.3 3.7 8.0 0.0 5.6 7 0 0 7 7 3 0 PPR repeat ChAPs PF09295.10 CBZ31392.1 - 0.04 12.9 0.7 0.6 9.1 0.0 2.7 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 CBZ31392.1 - 0.17 11.8 0.0 0.17 11.8 0.0 11.0 12 0 0 12 12 11 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CBZ31392.1 - 0.18 11.1 54.6 0.1 11.9 0.7 8.8 6 2 1 8 8 8 0 MalT-like TPR region MIT PF04212.18 CBZ31392.1 - 3 8.0 9.6 27 4.9 0.6 5.2 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 CBZ31392.1 - 3 7.2 20.5 0.73 9.2 1.3 6.0 6 0 0 6 6 6 0 Soluble NSF attachment protein, SNAP TPR_21 PF09976.9 CBZ31392.1 - 8 6.1 54.8 0.082 12.6 4.1 9.1 9 2 1 10 10 10 0 Tetratricopeptide repeat-like domain Y_phosphatase2 PF03162.13 CBZ31393.1 - 1.2e-51 174.6 0.0 1.6e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CBZ31393.1 - 2e-09 37.7 0.0 2.9e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBZ31393.1 - 0.0086 15.7 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CBZ31393.1 - 0.04 13.7 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBZ31393.1 - 0.21 11.7 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate TMV_coat PF00721.21 CBZ31393.1 - 0.31 10.8 1.5 3.7 7.4 0.0 2.7 2 1 1 3 3 3 0 Virus coat protein (TMV like) SOG2 PF10428.9 CBZ31393.1 - 5.1 6.2 8.7 5.9 6.0 8.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DENN PF02141.21 CBZ31394.1 - 4.5e-10 39.8 1.2 1.2e-09 38.3 1.2 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain Spermine_synth PF01564.17 CBZ31395.1 - 1.3e-48 165.0 0.0 2.5e-48 164.0 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CBZ31395.1 - 2.4e-16 59.4 0.0 4.7e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CBZ31395.1 - 0.00097 19.8 0.0 0.0017 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ31395.1 - 0.023 15.4 0.1 0.12 13.2 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain CRM1_repeat_2 PF18784.1 CBZ31395.1 - 0.099 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 BaxI_1 PF12811.7 CBZ31396.1 - 0.03 13.9 0.2 0.079 12.5 0.1 1.6 1 1 0 1 1 1 0 Bax inhibitor 1 like DUF1616 PF07760.11 CBZ31396.1 - 0.073 12.4 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) NPDC1 PF06809.11 CBZ31396.1 - 0.084 11.9 1.1 0.12 11.4 0.3 1.6 1 1 1 2 2 2 0 Neural proliferation differentiation control-1 protein (NPDC1) Glyco_trans_1_2 PF13524.6 CBZ31396.1 - 0.17 12.3 3.5 0.52 10.7 3.5 1.9 1 1 1 2 2 2 0 Glycosyl transferases group 1 Ank_2 PF12796.7 CBZ31397.1 - 1.6e-13 51.0 1.9 0.015 15.9 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ31397.1 - 6e-11 42.7 8.4 0.0025 18.4 0.1 6.1 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ31397.1 - 1.5e-10 41.1 9.5 0.00025 21.3 0.2 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CBZ31397.1 - 1e-09 38.4 11.1 0.048 14.1 0.2 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 CBZ31397.1 - 7.5e-09 35.1 7.0 0.12 13.0 0.1 6.2 6 0 0 6 6 6 3 Ankyrin repeat DUF1168 PF06658.12 CBZ31398.1 - 0.014 15.2 14.8 0.019 14.8 14.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Cu-oxidase_4 PF02578.15 CBZ31398.1 - 0.02 14.5 0.8 0.024 14.2 0.8 1.1 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase TFIIA PF03153.13 CBZ31398.1 - 0.15 12.0 8.2 0.16 12.0 8.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 CBZ31398.1 - 1.6 8.4 19.5 2 8.1 19.5 1.2 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MDFI PF15316.6 CBZ31398.1 - 2 8.5 7.9 3.1 7.9 7.9 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Vir_act_alpha_C PF10400.9 CBZ31398.1 - 2 9.1 9.9 1.1 10.0 6.2 2.4 1 1 2 3 3 3 0 Virulence activator alpha C-term TFIID-18kDa PF02269.16 CBZ31401.1 - 0.062 13.3 0.4 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit zf-C3HC4_3 PF13920.6 CBZ31402.1 - 8.4e-09 35.2 9.2 1.5e-08 34.3 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ31402.1 - 1.9e-07 30.8 9.2 3.4e-07 30.0 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ31402.1 - 1.8e-05 25.0 12.6 4.1e-05 23.8 12.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CBZ31402.1 - 0.0033 17.3 10.2 0.0072 16.3 10.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBZ31402.1 - 0.0079 16.0 11.4 0.018 14.9 11.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ31402.1 - 0.048 13.7 10.5 0.11 12.5 10.4 1.7 1 1 0 1 1 1 0 RING-type zinc-finger TMEM154 PF15102.6 CBZ31402.1 - 0.33 10.8 0.9 0.62 10.0 0.3 1.7 1 1 0 1 1 1 0 TMEM154 protein family Baculo_IE-1 PF05290.11 CBZ31402.1 - 0.36 10.8 4.3 0.76 9.7 4.3 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 CBZ31402.1 - 0.57 10.0 8.4 1.2 9.0 8.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 CBZ31403.1 - 1.5e-38 132.7 0.0 4.8e-10 39.3 0.0 6.1 6 0 0 6 6 6 5 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31403.1 - 2.6e-13 49.9 0.0 3.9e-08 32.9 0.1 4.1 4 0 0 4 4 4 3 Protein tyrosine kinase FHA PF00498.26 CBZ31403.1 - 9e-11 42.0 0.0 2.4e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 FHA domain TGS PF02824.21 CBZ31403.1 - 0.13 12.3 0.0 0.49 10.5 0.0 2.0 1 0 0 1 1 1 0 TGS domain Pkinase_fungal PF17667.1 CBZ31403.1 - 0.48 9.2 2.4 1.7 7.4 2.4 2.0 1 1 0 1 1 1 0 Fungal protein kinase UQ_con PF00179.26 CBZ31406.1 - 2.3e-46 157.0 0.1 2.5e-46 156.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBZ31406.1 - 0.004 16.9 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CBZ31406.1 - 0.0059 16.5 0.2 0.013 15.3 0.2 1.6 1 1 0 1 1 1 1 UEV domain Ax_dynein_light PF10211.9 CBZ31407.1 - 6.5e-10 39.2 2.7 6.5e-10 39.2 2.7 2.6 2 1 0 2 2 2 1 Axonemal dynein light chain CALM_bind PF16025.5 CBZ31407.1 - 0.15 12.6 4.1 5.8 7.4 0.3 2.9 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding HA PF03457.14 CBZ31407.1 - 0.31 11.4 2.3 1.5 9.3 0.1 2.4 2 0 0 2 2 2 0 Helicase associated domain CesT PF05932.13 CBZ31409.1 - 1e-09 38.6 0.1 2.8e-09 37.1 0.1 1.8 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family PDZ_2 PF13180.6 CBZ31409.1 - 1.8e-09 37.8 0.1 2.6e-06 27.6 0.2 2.6 2 0 0 2 2 2 2 PDZ domain PDZ_6 PF17820.1 CBZ31409.1 - 5.4e-05 23.0 0.2 5.4e-05 23.0 0.2 3.1 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 CBZ31409.1 - 0.11 12.8 0.0 3.3 8.1 0.0 2.6 2 0 0 2 2 2 0 PDZ domain Meiotic_rec114 PF03525.14 CBZ31409.1 - 0.23 10.4 1.4 0.43 9.5 1.4 1.4 1 0 0 1 1 1 0 Meiotic recombination protein rec114 DUF974 PF06159.13 CBZ31411.1 - 3.2e-10 40.2 0.0 5.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DUF348 PF03990.14 CBZ31411.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain WASH_WAHD PF11945.8 CBZ31412.1 - 6.3e-07 29.2 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex XRCC4 PF06632.12 CBZ31412.1 - 2.7 6.8 6.5 4.3 6.1 6.5 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Ribosomal_L16 PF00252.18 CBZ31413.1 - 7.7e-39 132.7 0.3 9.5e-39 132.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF3212 PF11486.8 CBZ31413.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3212) NAC PF01849.18 CBZ31414.1 - 7.7e-16 57.8 0.1 1.1e-15 57.3 0.1 1.2 1 0 0 1 1 1 1 NAC domain NAC PF01849.18 CBZ31415.1 - 3.9e-16 58.7 0.1 9.5e-16 57.5 0.1 1.7 1 0 0 1 1 1 1 NAC domain Myc_N PF01056.18 CBZ31415.1 - 0.057 13.3 3.2 0.067 13.1 3.2 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DnaJ PF00226.31 CBZ31416.1 - 1.9e-18 66.3 0.2 2.9e-18 65.7 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 CBZ31416.1 - 1.3e-06 28.4 5.6 5.4e-06 26.3 3.3 2.8 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein BRCT_2 PF16589.5 CBZ31419.1 - 1.5e-10 41.3 0.0 3.3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CBZ31419.1 - 5.2e-07 29.9 0.0 1.3e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Pescadillo_N PF06732.11 CBZ31419.1 - 8.2e-06 25.6 1.4 9.9e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.26 CBZ31419.1 - 1.9e-05 24.9 0.0 4.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Pep_deformylase PF01327.21 CBZ31420.1 - 4.3e-17 62.2 0.0 1.4e-16 60.5 0.0 1.8 1 1 0 1 1 1 1 Polypeptide deformylase DUF1523 PF07509.11 CBZ31420.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) Y_phosphatase2 PF03162.13 CBZ31422.1 - 3.1e-55 186.2 0.0 4.1e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CBZ31422.1 - 0.0031 17.5 0.0 0.0048 16.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Rhomboid PF01694.22 CBZ31423.1 - 1e-08 35.3 1.8 2.4e-08 34.1 1.8 1.6 1 0 0 1 1 1 1 Rhomboid family TPR_8 PF13181.6 CBZ31427.1 - 9.9e-06 25.4 0.1 0.00023 21.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ31427.1 - 0.00031 21.0 0.1 0.022 15.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ31427.1 - 0.0013 18.4 0.1 0.003 17.2 0.1 1.6 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 CBZ31427.1 - 0.0092 16.0 0.2 0.041 14.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 CBZ31427.1 - 0.0094 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 CBZ31427.1 - 0.014 15.2 0.7 0.037 13.9 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat IQ PF00612.27 CBZ31427.1 - 0.04 13.7 0.2 0.11 12.4 0.2 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Cmc1 PF08583.10 CBZ31431.1 - 0.0002 21.3 1.2 0.00028 20.8 1.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 CBZ31431.1 - 0.019 15.2 0.2 0.027 14.7 0.2 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DnaJ_C PF01556.18 CBZ31432.1 - 2.5e-35 121.7 0.0 3.4e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ31432.1 - 2.3e-21 75.7 0.7 4.4e-21 74.8 0.4 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ31432.1 - 4.6e-08 33.3 23.2 9.4e-08 32.3 23.2 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ31432.1 - 0.8 9.7 22.3 0.55 10.2 3.8 2.7 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Ribosomal_L16 PF00252.18 CBZ31433.1 - 0.15 12.0 0.1 0.17 11.9 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L16p/L10e ADK PF00406.22 CBZ31434.1 - 1.8e-38 132.0 0.0 2.2e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ31434.1 - 7e-30 104.2 0.0 9.4e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ31434.1 - 2.3e-06 28.2 0.0 4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBZ31434.1 - 7.1e-06 26.2 0.0 1.7e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 CBZ31434.1 - 0.017 15.0 0.1 0.069 13.0 0.0 1.8 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_28 PF13521.6 CBZ31434.1 - 0.019 15.2 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 CBZ31434.1 - 0.1 12.2 0.1 1.9 8.1 0.0 2.2 1 1 0 2 2 2 0 Thymidylate kinase Nop14 PF04147.12 CBZ31438.1 - 1.2e-05 23.8 19.0 1.6e-05 23.4 19.0 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 CBZ31438.1 - 0.002 17.6 20.8 0.0022 17.5 20.8 1.1 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.10 CBZ31438.1 - 0.0052 16.2 18.9 0.0057 16.1 18.9 1.2 1 0 0 1 1 1 1 BUD22 RNA_pol_3_Rpc31 PF11705.8 CBZ31438.1 - 0.0056 17.0 15.7 0.011 16.0 15.7 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 CBZ31438.1 - 0.016 13.5 16.2 0.021 13.2 16.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 CBZ31438.1 - 0.18 10.8 3.6 0.26 10.2 3.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 CBZ31438.1 - 0.63 8.8 5.7 0.71 8.6 5.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PNISR PF15996.5 CBZ31438.1 - 1.8 8.8 12.4 3 8.1 12.4 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DNA_pol_phi PF04931.13 CBZ31438.1 - 2.8 5.9 30.1 3.9 5.5 30.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIF_alpha PF05793.12 CBZ31438.1 - 3.8 6.0 22.5 5.7 5.4 22.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 CBZ31438.1 - 4.5 5.9 5.0 5.3 5.7 5.0 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CBZ31438.1 - 7.1 4.6 5.8 9.1 4.3 5.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Voltage_CLC PF00654.20 CBZ31439.1 - 3.5e-87 293.0 29.3 3.5e-87 293.0 29.3 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CBZ31439.1 - 7.1e-07 29.6 1.2 0.04 14.4 0.0 3.4 3 0 0 3 3 3 2 CBS domain RRP36 PF06102.12 CBZ31440.1 - 9.2e-33 113.5 11.9 2.2e-32 112.3 11.9 1.5 1 1 0 1 1 1 1 rRNA biogenesis protein RRP36 COPI_assoc PF08507.10 CBZ31441.1 - 1.9e-07 31.2 11.6 2.4e-07 30.8 11.6 1.1 1 0 0 1 1 1 1 COPI associated protein Neurensin PF14927.6 CBZ31441.1 - 0.44 10.2 8.5 0.91 9.2 0.1 2.6 1 1 1 2 2 2 0 Neurensin DUF1218 PF06749.12 CBZ31441.1 - 0.64 10.6 7.4 0.17 12.4 2.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) DUF4191 PF13829.6 CBZ31441.1 - 2.2 7.6 6.1 7 5.9 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Chordopox_L2 PF05803.12 CBZ31441.1 - 8.3 6.3 8.4 0.52 10.2 2.5 1.8 2 0 0 2 2 2 0 Chordopoxvirus L2 protein Acyltransferase PF01553.21 CBZ31442.1 - 6.6e-12 45.2 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF2919 PF11143.8 CBZ31442.1 - 0.45 10.8 7.0 0.69 10.2 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2919) Acyltransferase PF01553.21 CBZ31443.1 - 1.9e-11 43.7 0.1 3e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4386 PF14329.6 CBZ31443.1 - 0.13 12.1 1.9 0.2 11.5 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Macoilin PF09726.9 CBZ31444.1 - 1.1 7.8 2.6 0.43 9.1 0.1 1.5 2 0 0 2 2 2 0 Macoilin family PBP_N PF17093.5 CBZ31444.1 - 5.2 7.3 6.8 13 6.0 0.0 3.6 3 0 0 3 3 3 0 Penicillin-binding protein N-terminus Parvo_coat PF00740.18 CBZ31445.1 - 0.15 10.7 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Tcf25 PF04910.14 CBZ31446.1 - 2.3e-38 132.2 0.0 3.7e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Rrn6 PF10214.9 CBZ31446.1 - 0.24 9.9 11.6 0.35 9.3 11.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SUIM_assoc PF16619.5 CBZ31446.1 - 6.1 7.0 11.1 1.5 8.9 7.3 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Striatin PF08232.12 CBZ31448.1 - 0.0027 18.3 1.1 0.0027 18.3 1.1 6.4 2 2 4 6 6 6 1 Striatin family PKcGMP_CC PF16808.5 CBZ31448.1 - 3.9 7.4 8.8 5.9 6.8 1.5 4.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FCH PF00611.23 CBZ31449.1 - 0.043 14.1 0.5 0.1 12.9 0.2 1.8 1 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain E1-E2_ATPase PF00122.20 CBZ31450.1 - 6.8e-23 81.1 0.3 6.8e-23 81.1 0.3 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBZ31450.1 - 1.1e-13 52.0 0.4 4.3e-06 27.2 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase 3HCDH_RFF PF18321.1 CBZ31450.1 - 0.94 10.0 11.2 0.4 11.2 0.8 4.1 4 0 0 4 4 4 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain SCO1-SenC PF02630.14 CBZ31452.1 - 4.7e-45 152.8 0.0 7e-45 152.2 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CBZ31452.1 - 0.0084 16.0 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family FBPase PF00316.20 CBZ31455.1 - 5.6e-59 198.8 0.1 7.2e-59 198.4 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain RRM_1 PF00076.22 CBZ31457.1 - 2.4e-13 49.7 0.0 1.4e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ31457.1 - 6.4e-09 35.5 0.1 0.00041 19.9 0.1 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ31457.1 - 0.00025 20.8 0.2 0.0041 17.0 0.1 2.4 2 1 0 2 2 2 1 Occluded RNA-recognition motif CDC48_2 PF02933.17 CBZ31457.1 - 0.0021 17.8 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RRM_8 PF11835.8 CBZ31457.1 - 0.0041 17.3 0.1 0.014 15.6 0.1 1.9 2 0 0 2 2 2 1 RRM-like domain DUF5399 PF17377.2 CBZ31457.1 - 0.056 13.3 0.4 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5399) MOEP19 PF16005.5 CBZ31457.1 - 0.15 12.1 0.3 0.57 10.2 0.1 1.9 2 0 0 2 2 2 0 KH-like RNA-binding domain PolyA_pol PF01743.20 CBZ31459.1 - 2.9e-29 102.1 0.0 5.2e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CBZ31459.1 - 9.1e-07 28.5 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A LRR_6 PF13516.6 CBZ31460.1 - 2.9e-05 23.7 0.3 0.25 11.5 0.0 3.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 CBZ31460.1 - 0.018 15.4 0.5 0.1 13.1 0.2 2.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) US6 PF17616.2 CBZ31460.1 - 0.072 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Viral unique short region 6 LRR_8 PF13855.6 CBZ31460.1 - 0.092 12.5 0.7 1.6 8.6 0.4 2.6 2 1 1 3 3 3 0 Leucine rich repeat Pkinase PF00069.25 CBZ31461.1 - 1.9e-25 89.7 0.0 2.3e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31461.1 - 1.9e-17 63.4 0.0 2.8e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ31461.1 - 1.6e-06 27.2 0.0 1.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ31461.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Actin PF00022.19 CBZ31463.1 - 7.9e-142 472.6 0.0 6.8e-141 469.6 0.0 1.9 1 1 0 1 1 1 1 Actin ATG16 PF08614.11 CBZ31464.1 - 0.012 15.9 27.6 0.012 15.9 27.6 8.0 3 2 4 7 7 7 0 Autophagy protein 16 (ATG16) SUI1 PF01253.22 CBZ31464.1 - 0.066 13.8 0.1 0.27 11.8 0.1 2.0 1 0 0 1 1 1 0 Translation initiation factor SUI1 Peptidase_S7 PF00949.21 CBZ31464.1 - 0.13 12.1 0.3 2.8 7.8 0.1 2.9 2 1 1 3 3 3 0 Peptidase S7, Flavivirus NS3 serine protease MS_channel PF00924.18 CBZ31464.1 - 0.26 10.8 1.1 0.93 9.0 0.4 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel DUF3502 PF12010.8 CBZ31464.1 - 4.3 8.0 7.5 0.52 11.0 1.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3502) Arf PF00025.21 CBZ31466.1 - 4e-54 182.7 0.0 4.5e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CBZ31466.1 - 8.7e-09 35.0 0.8 6.5e-06 25.5 0.0 2.6 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CBZ31466.1 - 2.6e-08 33.5 0.0 3.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBZ31466.1 - 6.9e-08 32.6 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CBZ31466.1 - 7.5e-08 32.6 0.0 1.8e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ31466.1 - 2.7e-07 30.3 0.0 3.4e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 CBZ31466.1 - 6.1e-05 22.6 0.1 0.021 14.4 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBZ31466.1 - 0.00018 20.9 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 CBZ31466.1 - 0.014 15.0 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 CBZ31466.1 - 0.041 13.4 0.1 0.21 11.1 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B SRP54 PF00448.22 CBZ31466.1 - 0.068 12.8 0.2 0.15 11.7 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Bacillus_HBL PF05791.11 CBZ31467.1 - 0.82 9.5 28.3 0.025 14.4 2.0 5.3 2 1 3 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) Cor1 PF04803.12 CBZ31468.1 - 0.00018 21.7 0.9 0.00018 21.7 0.9 3.6 4 1 0 4 4 4 1 Cor1/Xlr/Xmr conserved region Apolipoprotein PF01442.18 CBZ31468.1 - 0.00086 19.2 16.2 0.00086 19.2 16.2 4.6 4 1 1 5 5 5 1 Apolipoprotein A1/A4/E domain eIF3_N PF09440.10 CBZ31468.1 - 0.0086 16.5 1.4 0.0086 16.5 1.4 4.9 2 2 3 5 5 5 1 eIF3 subunit 6 N terminal domain DUF1878 PF08963.10 CBZ31468.1 - 0.0092 16.5 0.7 0.0092 16.5 0.7 2.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1878) MVP_shoulder PF11978.8 CBZ31469.1 - 1.4e-47 160.6 0.1 2.7e-47 159.7 0.1 1.5 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.18 CBZ31469.1 - 1.5e-45 153.0 3.8 6.7e-12 45.4 0.1 4.8 4 0 0 4 4 4 4 Major Vault Protein repeat domain Vault_3 PF17795.1 CBZ31469.1 - 1e-31 108.8 2.5 3.1e-30 104.0 0.2 3.7 4 0 0 4 4 4 1 Major Vault Protein Repeat domain Vault_2 PF17794.1 CBZ31469.1 - 1.3e-30 105.5 0.3 1.4e-21 76.6 0.2 3.0 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_4 PF17796.1 CBZ31469.1 - 2.4e-20 72.4 0.1 1.5e-19 69.8 0.1 2.4 2 0 0 2 2 2 1 Major Vault Protein repeat domain DUF3601 PF12208.8 CBZ31469.1 - 0.0098 16.0 0.0 4.6 7.4 0.0 3.5 2 1 1 3 3 3 1 Domain of unknown function (DUF3601) Dynein_light PF01221.18 CBZ31470.1 - 7.3e-30 103.1 0.7 8.6e-30 102.9 0.7 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Vasohibin PF14822.6 CBZ31470.1 - 0.0013 18.1 0.1 0.0016 17.7 0.1 1.3 1 1 0 1 1 1 1 Vasohibin Rrp15p PF07890.12 CBZ31471.1 - 2.6e-10 40.7 9.8 6.3e-10 39.5 9.8 1.6 1 1 0 1 1 1 1 Rrp15p NUDIX PF00293.28 CBZ31472.1 - 1.8e-15 57.2 0.0 2.5e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.28 CBZ31473.1 - 1.2e-26 94.5 0.1 1.9e-26 93.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Plus-3 PF03126.18 CBZ31473.1 - 1.7e-06 28.5 0.0 3.2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain Methyltransf_4 PF02390.17 CBZ31475.1 - 0.037 13.5 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Pkinase PF00069.25 CBZ31476.1 - 1.3e-55 188.7 0.0 2e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31476.1 - 1.5e-29 103.1 0.0 2.3e-26 92.7 0.1 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ31476.1 - 7e-06 25.1 0.0 9e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ31476.1 - 0.0017 18.4 0.1 0.0058 16.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ31476.1 - 0.0071 15.3 0.4 0.011 14.7 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CBZ31476.1 - 0.0073 15.8 0.2 0.011 15.2 0.2 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 CBZ31476.1 - 0.025 14.2 1.3 0.041 13.5 0.5 1.6 1 1 0 1 1 1 0 RIO1 family DEAD PF00270.29 CBZ31477.1 - 1e-41 142.6 0.0 5.2e-41 140.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ31477.1 - 1.3e-30 106.0 0.0 2.2e-28 98.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 CBZ31477.1 - 1.4e-19 70.2 0.0 3.6e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 GUCT (NUC152) domain ERCC3_RAD25_C PF16203.5 CBZ31477.1 - 9.7e-05 21.7 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CBZ31477.1 - 0.028 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit LRR_6 PF13516.6 CBZ31478.1 - 3e-34 114.1 23.9 1.6e-05 24.6 0.0 10.1 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.7 CBZ31478.1 - 1.2e-10 41.5 11.1 9.7e-06 25.9 0.1 5.4 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ31478.1 - 1.9e-10 39.8 0.4 2.3 9.1 0.0 7.3 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 CBZ31478.1 - 2.1e-06 27.4 8.6 0.18 11.6 0.9 5.9 6 1 0 6 6 6 2 Leucine rich repeat IFRD PF05004.13 CBZ31478.1 - 0.00051 19.3 0.6 0.00074 18.7 0.6 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Fez1 PF06818.15 CBZ31479.1 - 0.048 14.1 36.0 0.23 11.9 10.3 2.4 2 0 0 2 2 2 0 Fez1 2-oxoacid_dh PF00198.23 CBZ31481.1 - 6.9e-80 267.8 0.1 8.8e-80 267.5 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CBZ31481.1 - 5.3e-17 61.4 1.2 1.4e-16 60.1 0.4 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 CBZ31481.1 - 4.1e-15 55.8 0.1 1e-14 54.5 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain Fip1 PF05182.13 CBZ31482.1 - 1.8e-18 65.8 0.3 3.1e-18 65.0 0.3 1.4 1 0 0 1 1 1 1 Fip1 motif zf-CCCH PF00642.24 CBZ31482.1 - 1.1e-10 41.1 3.0 2.4e-10 40.0 3.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ31482.1 - 2.2e-05 24.4 5.1 3.9e-05 23.6 5.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBZ31482.1 - 4.8e-05 23.1 3.3 8.1e-05 22.3 3.3 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CBZ31482.1 - 0.00088 19.9 1.2 0.0017 19.0 1.2 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CBZ31482.1 - 0.042 14.3 2.3 0.072 13.6 2.3 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger MMR_HSR1 PF01926.23 CBZ31483.1 - 1.4e-14 54.2 0.0 1.3e-13 51.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ31483.1 - 4.2e-06 26.4 0.0 1.6e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ31483.1 - 3.3e-05 23.9 0.0 0.36 10.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CBZ31483.1 - 0.00027 20.3 0.0 0.00055 19.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 CBZ31483.1 - 0.51 10.7 0.0 0.51 10.7 0.0 3.5 1 1 2 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.23 CBZ31483.1 - 0.71 9.9 2.3 0.75 9.8 0.1 2.2 2 1 0 2 2 2 0 Dynamin family DSPc PF00782.20 CBZ31485.1 - 1.2e-32 112.5 0.1 1.8e-32 111.9 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ31485.1 - 8.5e-05 22.2 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 CBZ31485.1 - 0.0079 15.8 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 CBZ31485.1 - 0.033 14.5 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain Myotub-related PF06602.14 CBZ31485.1 - 0.17 10.8 0.1 0.26 10.2 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Fe_hyd_lg_C PF02906.14 CBZ31486.1 - 5.3e-58 196.5 0.1 1.5e-57 195.1 0.0 1.7 2 0 0 2 2 2 1 Iron only hydrogenase large subunit, C-terminal domain Ank_3 PF13606.6 CBZ31489.1 - 0.00013 22.1 0.0 0.0004 20.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.6 CBZ31489.1 - 0.00071 20.1 0.1 0.0017 18.8 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ31489.1 - 0.0011 19.5 0.0 0.003 18.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBZ31489.1 - 0.0031 17.8 0.0 0.0082 16.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CBZ31489.1 - 0.019 15.4 0.1 0.041 14.3 0.1 1.6 1 0 0 1 1 1 0 Ankyrin repeat IATP PF04568.12 CBZ31489.1 - 0.047 14.1 1.3 0.047 14.1 1.3 2.5 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Pinin_SDK_memA PF04696.13 CBZ31489.1 - 3.1 7.9 13.2 30 4.7 10.4 2.2 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region PTPLA PF04387.14 CBZ31491.1 - 7.9e-56 188.3 6.1 9.8e-56 188.0 6.1 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA P16-Arc PF04699.14 CBZ31492.1 - 4.8e-05 23.9 0.0 6.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Mito_carr PF00153.27 CBZ31493.1 - 6.8e-40 134.9 12.8 3e-13 49.5 0.0 4.7 5 0 0 5 5 5 3 Mitochondrial carrier protein DUF3446 PF11928.8 CBZ31493.1 - 0.17 12.2 1.6 1.2 9.5 0.3 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain Glutaredoxin PF00462.24 CBZ31495.1 - 3e-15 56.2 0.0 4.3e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin FAD-SLDH PF12318.8 CBZ31495.1 - 0.071 13.2 0.8 0.1 12.7 0.8 1.2 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase RdRP PF05183.12 CBZ31495.1 - 0.15 10.7 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase MCM PF00493.23 CBZ31496.1 - 7.3e-70 234.6 0.0 1.1e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CBZ31496.1 - 1.5e-14 54.2 0.5 9.3e-09 35.6 0.5 2.4 2 0 0 2 2 2 2 MCM AAA-lid domain MCM_OB PF17207.3 CBZ31496.1 - 2.3e-10 40.4 0.9 2.9e-09 36.8 0.1 2.4 2 0 0 2 2 2 1 MCM OB domain AAA_5 PF07728.14 CBZ31496.1 - 1.2e-08 35.1 0.0 2.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBZ31496.1 - 0.00025 20.5 0.2 0.11 11.9 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBZ31496.1 - 0.00033 20.5 0.0 0.00083 19.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBZ31496.1 - 0.011 15.4 0.1 0.044 13.5 0.1 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 CBZ31496.1 - 0.024 15.1 0.1 0.074 13.5 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ31496.1 - 0.065 13.6 0.8 0.17 12.3 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_2 PF07724.14 CBZ31496.1 - 0.2 11.8 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Ribosomal_S11 PF00411.19 CBZ31497.1 - 0.00011 22.6 0.6 0.0003 21.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S11 Pyr_redox_2 PF07992.14 CBZ31498.1 - 4.3e-61 206.7 0.2 6.7e-61 206.1 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBZ31498.1 - 8.8e-26 90.3 0.2 1.6e-25 89.5 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBZ31498.1 - 1.9e-19 70.0 0.3 5e-17 62.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBZ31498.1 - 3.9e-11 42.8 0.2 1.3e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ31498.1 - 0.00039 19.2 1.3 0.56 8.8 0.7 2.5 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 CBZ31498.1 - 0.00099 18.3 4.5 0.041 13.0 1.9 2.3 2 0 0 2 2 2 2 FAD binding domain PALP PF00291.25 CBZ31498.1 - 0.024 14.1 0.1 0.051 13.0 0.1 1.6 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme GIDA PF01134.22 CBZ31498.1 - 0.066 12.3 0.4 0.13 11.4 0.4 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 CBZ31498.1 - 0.08 12.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus DEAD PF00270.29 CBZ31499.1 - 3.9e-42 144.0 0.0 6.5e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ31499.1 - 2.2e-24 85.9 0.0 5.3e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ31499.1 - 0.00013 22.0 0.0 0.00044 20.3 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ31499.1 - 0.083 13.2 0.0 0.29 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF1143 PF06608.11 CBZ31500.1 - 0.14 12.2 0.1 0.41 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1143) Pkinase PF00069.25 CBZ31502.1 - 3e-68 230.0 0.0 3.9e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31502.1 - 2.6e-49 167.9 0.0 3.8e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase MORN PF02493.20 CBZ31502.1 - 8.3e-42 138.6 47.5 4.6e-10 38.8 3.8 8.7 8 0 0 8 8 8 8 MORN repeat Pkinase_fungal PF17667.1 CBZ31502.1 - 0.00011 21.1 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ31502.1 - 0.0024 17.2 0.0 0.013 14.9 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CBZ31502.1 - 0.0038 16.2 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CBZ31502.1 - 0.077 12.6 0.0 0.48 10.0 0.0 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 CBZ31502.1 - 0.16 11.9 0.1 2.1 8.2 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SMC_N PF02463.19 CBZ31503.1 - 4.6e-59 199.5 0.0 8.1e-59 198.7 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBZ31503.1 - 3.2e-13 50.2 0.8 7.2e-06 26.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ31503.1 - 8.5e-11 42.7 15.7 8.5e-11 42.7 15.7 6.5 2 2 1 4 4 4 1 AAA domain SMC_hinge PF06470.13 CBZ31503.1 - 1.9e-09 37.9 0.1 9.5e-09 35.6 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CBZ31503.1 - 2.4e-06 27.5 8.6 5.2e-06 26.4 0.2 3.6 2 2 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CBZ31503.1 - 9e-05 22.1 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CBZ31503.1 - 0.65 10.5 22.6 2.1 8.8 0.0 5.9 3 2 0 3 3 3 0 ABC transporter TPR_2 PF07719.17 CBZ31504.1 - 4e-23 79.6 17.0 0.0006 19.7 0.1 9.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ31504.1 - 1.8e-16 59.2 8.4 0.026 14.4 0.1 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ31504.1 - 7.6e-13 48.1 41.9 0.0028 18.3 0.4 10.7 7 1 5 12 12 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ31504.1 - 9.8e-11 41.8 35.8 0.00056 20.1 0.6 9.3 7 1 3 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ31504.1 - 1.2e-09 38.6 36.1 3.7e-05 24.1 0.5 8.6 5 1 2 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ31504.1 - 1.4e-08 34.8 24.2 0.015 15.5 0.3 6.1 5 1 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CBZ31504.1 - 1.5e-07 31.9 51.0 0.013 16.1 4.5 8.7 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ31504.1 - 1.7e-07 31.2 6.2 0.00062 20.0 0.0 6.6 8 1 0 8 8 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ31504.1 - 1.3e-06 28.1 2.4 2.2 8.7 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ31504.1 - 4.8e-06 26.2 5.7 0.49 10.1 0.0 5.9 5 1 1 6 6 6 1 TPR repeat TPR_6 PF13174.6 CBZ31504.1 - 5e-05 23.7 20.0 0.69 10.7 0.0 8.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ31504.1 - 5.4e-05 23.3 1.5 5.4e-05 23.3 1.5 6.1 4 1 2 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ31504.1 - 0.0003 20.8 0.9 0.12 12.5 0.2 4.0 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 CBZ31504.1 - 0.00041 20.2 9.6 3.5 7.9 0.1 6.4 5 1 2 7 7 7 1 Tetratricopeptide repeat BTAD PF03704.17 CBZ31504.1 - 0.0015 19.0 3.9 0.0015 19.0 3.9 4.9 3 1 0 5 5 5 1 Bacterial transcriptional activator domain NARP1 PF12569.8 CBZ31504.1 - 0.041 12.8 1.1 2.8 6.8 0.0 2.3 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 HEAT_2 PF13646.6 CBZ31504.1 - 1.8 9.0 9.4 1.4 9.4 0.3 3.6 3 0 0 3 3 3 0 HEAT repeats Tctex-1 PF03645.13 CBZ31505.1 - 6.9e-25 87.3 0.8 7.7e-25 87.1 0.8 1.0 1 0 0 1 1 1 1 Tctex-1 family Metallophos PF00149.28 CBZ31506.1 - 0.003 18.1 0.0 0.078 13.5 0.0 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase NGP1NT PF08153.12 CBZ31509.1 - 1.1e-44 151.7 0.6 2.6e-44 150.5 0.6 1.7 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CBZ31509.1 - 1.7e-18 66.7 0.2 7.8e-15 55.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ31509.1 - 1.4e-05 24.7 0.1 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CBZ31509.1 - 0.00079 19.0 0.0 0.22 11.0 0.0 3.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ31509.1 - 0.0012 18.8 0.0 0.024 14.6 0.0 2.4 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CBZ31509.1 - 0.035 14.5 1.8 0.096 13.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 CBZ31509.1 - 0.061 13.5 0.1 9.2 6.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CBZ31509.1 - 0.064 13.3 11.3 0.69 9.9 0.0 4.5 4 2 1 5 5 5 0 Dynamin family Ras PF00071.22 CBZ31509.1 - 0.14 11.7 0.2 5.8 6.5 0.0 2.6 2 0 0 2 2 2 0 Ras family DUF2956 PF11169.8 CBZ31509.1 - 3.6 7.8 9.3 2.9 8.1 3.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) MFS_1 PF07690.16 CBZ31511.1 - 4.7e-28 98.1 34.5 6.5e-20 71.3 5.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1304 PF06993.12 CBZ31511.1 - 2.2 8.3 13.2 2.4 8.2 0.8 3.4 2 1 2 4 4 4 0 Protein of unknown function (DUF1304) TDA11 PF17084.5 CBZ31512.1 - 0.23 10.4 0.3 0.29 10.0 0.3 1.1 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 ATP-synt_ab PF00006.25 CBZ31514.1 - 3.2e-67 226.3 0.1 4.9e-67 225.7 0.1 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CBZ31514.1 - 7.1e-09 36.1 0.8 4.9e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain His_kinase PF06580.13 CBZ31514.1 - 1.3 9.4 4.7 1.1 9.6 0.4 2.4 1 1 1 2 2 2 0 Histidine kinase ADH_zinc_N PF00107.26 CBZ31515.1 - 2.5e-08 34.0 0.2 4.5e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBZ31515.1 - 0.0062 17.6 0.0 0.061 14.4 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ31515.1 - 0.031 14.1 0.1 0.077 12.9 0.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain LSM PF01423.22 CBZ31517.1 - 7.5e-06 25.5 0.2 4.9e-05 22.9 0.2 2.1 1 1 0 1 1 1 1 LSM domain Pkinase PF00069.25 CBZ31518.1 - 1.3e-67 227.9 0.0 1.5e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31518.1 - 2.3e-31 109.0 0.0 3e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBZ31518.1 - 0.00056 19.3 0.1 0.00093 18.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ31518.1 - 0.0031 17.5 0.0 0.036 14.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ31518.1 - 0.022 13.7 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CBZ31518.1 - 0.071 11.9 0.0 0.18 10.5 0.0 1.5 1 1 1 2 2 2 0 Fungal protein kinase Motile_Sperm PF00635.26 CBZ31519.1 - 0.0021 17.9 0.0 0.021 14.7 0.0 2.4 2 0 0 2 2 2 1 MSP (Major sperm protein) domain NDUF_B5 PF09781.9 CBZ31520.1 - 0.078 12.6 0.9 0.14 11.8 0.9 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit DUF2106 PF09879.9 CBZ31521.1 - 0.24 10.9 0.6 2.2 7.8 0.0 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2106) DEAD PF00270.29 CBZ31522.1 - 2.7e-32 112.0 0.1 8e-17 61.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ31522.1 - 1.3e-21 77.0 0.1 1.1e-20 74.0 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ31522.1 - 1.6e-05 25.0 0.0 4.3e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PBP1_TM PF14812.6 CBZ31522.1 - 0.00025 21.4 7.2 0.00095 19.5 7.2 2.0 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 CBZ31522.1 - 0.014 13.8 1.8 0.026 12.9 1.8 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA_22 PF13401.6 CBZ31522.1 - 0.12 12.7 0.1 2.8 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3245 PF11595.8 CBZ31522.1 - 0.4 11.1 11.4 3.4 8.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) RPN2_C PF18004.1 CBZ31522.1 - 5.4 6.9 5.5 1.9 8.4 2.0 1.9 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain COG4 PF08318.12 CBZ31523.1 - 2.1e-44 152.0 1.3 2.1e-44 152.0 1.3 1.9 2 1 0 2 2 2 1 COG4 transport protein RINT1_TIP1 PF04437.13 CBZ31523.1 - 0.0056 15.6 1.2 0.018 13.9 0.2 2.0 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Sec10 PF07393.11 CBZ31523.1 - 0.032 12.7 0.4 0.25 9.7 0.0 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec10 Surp PF01805.20 CBZ31524.1 - 1.9e-10 40.5 0.0 3.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Surp module SR-25 PF10500.9 CBZ31524.1 - 0.0014 18.3 17.3 0.0014 18.3 17.3 3.5 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein BBP1_N PF15271.6 CBZ31524.1 - 4.8 7.9 7.0 4.8 8.0 2.6 2.2 2 0 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein ubiquitin PF00240.23 CBZ31525.1 - 0.0034 17.1 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Kinesin PF00225.23 CBZ31526.1 - 2.2e-76 256.9 0.5 3.9e-76 256.1 0.5 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ31526.1 - 7.9e-11 42.1 0.4 1e-07 32.0 0.0 2.8 3 0 0 3 3 3 2 Microtubule binding Phlebovirus_NSM PF07246.11 CBZ31526.1 - 2.6 7.3 6.0 14 5.0 0.2 2.5 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M SUIM_assoc PF16619.5 CBZ31526.1 - 3.2 7.9 7.0 14 5.9 0.0 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 CBZ31527.1 - 2.5e-46 156.2 12.5 5.9e-11 42.8 0.0 11.3 10 2 2 12 12 12 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ31527.1 - 1.3e-34 118.1 15.9 3.1e-05 24.4 0.3 13.7 11 3 2 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ31527.1 - 5.5e-31 103.1 24.6 0.0081 16.6 0.0 17.0 17 0 0 17 17 17 7 Ankyrin repeat Ank_5 PF13857.6 CBZ31527.1 - 1.9e-25 88.6 16.8 0.00027 21.2 0.0 12.0 12 2 2 14 14 14 5 Ankyrin repeats (many copies) Ank PF00023.30 CBZ31527.1 - 1.4e-21 75.9 33.7 0.00018 21.8 0.0 16.4 17 0 0 17 17 17 7 Ankyrin repeat Gemini_AL2 PF01440.16 CBZ31527.1 - 0.11 13.0 0.1 0.35 11.3 0.1 1.8 1 0 0 1 1 1 0 Geminivirus AL2 protein LRR_6 PF13516.6 CBZ31528.1 - 0.00033 20.5 5.8 0.68 10.1 0.1 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 CBZ31528.1 - 0.0097 16.3 0.3 0.028 14.9 0.3 1.8 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ31528.1 - 0.051 13.3 1.3 0.34 10.7 1.4 2.3 1 1 0 1 1 1 0 Leucine rich repeat Nitroreductase PF00881.24 CBZ31529.1 - 3.4e-33 115.1 0.0 5e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 CBZ31529.1 - 0.047 13.3 0.0 3 7.4 0.0 2.3 2 0 0 2 2 2 0 Putative TM nitroreductase Mtc PF03820.17 CBZ31531.1 - 1.5e-92 310.0 0.5 1.8e-92 309.7 0.5 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SHIPPO-rpt PF07004.12 CBZ31532.1 - 5.8e-62 203.9 185.1 0.0031 18.3 0.7 40.7 41 0 0 41 41 41 33 Sperm-tail PG-rich repeat Cyclin PF08613.11 CBZ31534.1 - 9.8e-19 68.3 0.0 9.8e-19 68.3 0.0 3.6 4 0 0 4 4 4 1 Cyclin Cyclin_N PF00134.23 CBZ31534.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyocin_S PF06958.12 CBZ31534.1 - 1.1 9.7 7.4 2.4 8.7 0.9 3.5 2 0 0 2 2 2 0 S-type Pyocin DSPc PF00782.20 CBZ31535.1 - 1e-18 67.4 0.1 7.4e-07 29.1 0.0 3.3 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Vta1 PF04652.16 CBZ31537.1 - 6.7e-34 116.9 0.5 1.1e-33 116.2 0.5 1.3 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 CBZ31537.1 - 1.3e-13 50.4 1.8 1.3e-13 50.4 1.8 1.9 2 0 0 2 2 2 1 Vta1 C-terminal domain Radical_SAM PF04055.21 CBZ31538.1 - 1.1e-18 68.2 0.0 2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 CBZ31538.1 - 1.7e-18 66.7 0.8 4.9e-13 49.2 0.0 2.6 2 0 0 2 2 2 2 Wyosine base formation Flavodoxin_1 PF00258.25 CBZ31538.1 - 3.2e-12 46.9 0.0 2.2e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin Kinesin PF00225.23 CBZ31539.1 - 1.3e-81 274.1 0.0 4.6e-55 186.9 0.4 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ31539.1 - 2.9e-11 43.5 0.0 5.6e-09 36.1 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding MAM33 PF02330.16 CBZ31542.1 - 4.8e-14 52.8 0.0 1.1e-13 51.7 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial glycoprotein MbtH PF03621.13 CBZ31542.1 - 0.17 11.4 1.4 18 4.9 0.2 2.5 2 0 0 2 2 2 0 MbtH-like protein zf-MYND PF01753.18 CBZ31543.1 - 3.5e-11 43.0 12.6 3.5e-11 43.0 12.6 2.0 2 0 0 2 2 2 1 MYND finger Got1 PF04178.12 CBZ31544.1 - 2.2e-31 108.6 17.3 2.9e-31 108.2 17.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Bac_export_2 PF01312.19 CBZ31544.1 - 0.13 11.5 1.1 0.14 11.3 1.1 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family 7tm_3 PF00003.22 CBZ31544.1 - 0.25 11.0 17.0 0.87 9.3 16.5 1.7 1 1 1 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR DUF4064 PF13273.6 CBZ31544.1 - 1.9 8.8 14.5 16 5.9 14.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2721 PF11026.8 CBZ31544.1 - 5 7.0 16.2 4.8 7.1 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF1841 PF08897.11 CBZ31545.1 - 0.076 13.0 0.5 0.19 11.8 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1841) PNP_UDP_1 PF01048.20 CBZ31546.1 - 2.1e-37 128.7 0.3 2.6e-37 128.3 0.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily zf-C2HC_2 PF13913.6 CBZ31548.1 - 6.3e-14 51.5 9.8 1.6e-08 34.2 2.2 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.8 CBZ31548.1 - 0.024 14.4 4.1 1.7 8.4 0.0 2.4 3 0 0 3 3 3 0 CpG binding protein zinc finger C terminal domain zf-C2H2_11 PF16622.5 CBZ31548.1 - 0.073 12.8 0.3 9.4 6.1 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 CBZ31548.1 - 0.074 13.5 0.6 6.8 7.4 0.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBZ31548.1 - 0.075 13.9 1.1 2.9 9.0 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CBZ31548.1 - 0.5 10.5 3.4 15 5.8 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-FPG_IleRS PF06827.14 CBZ31548.1 - 1 9.3 7.3 4.6 7.2 0.2 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS SUIM_assoc PF16619.5 CBZ31548.1 - 3.8 7.7 12.3 8.2 6.6 0.0 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 MMS1_N PF10433.9 CBZ31552.1 - 6e-24 84.5 0.0 1.7e-13 50.1 0.0 3.2 4 0 0 4 4 4 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term YL1 PF05764.13 CBZ31552.1 - 0.019 15.1 1.1 0.019 15.1 1.1 2.0 2 0 0 2 2 2 0 YL1 nuclear protein DUF4228 PF14009.6 CBZ31552.1 - 2.6 8.4 6.2 3.2 8.1 2.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4228) LRR_8 PF13855.6 CBZ31553.1 - 9.2e-07 28.5 0.5 1.8e-05 24.4 0.3 2.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CBZ31553.1 - 0.0015 18.9 3.8 0.015 15.7 0.7 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CBZ31554.1 - 0.37 11.1 2.2 0.84 10.0 2.2 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Flagellar_rod PF05149.12 CBZ31555.1 - 1.9e-98 329.4 27.3 1.9e-98 329.4 27.3 2.1 3 0 0 3 3 3 1 Paraflagellar rod protein Jnk-SapK_ap_N PF09744.9 CBZ31555.1 - 0.0086 16.3 7.5 0.0086 16.3 7.5 4.1 3 1 1 4 4 4 1 JNK_SAPK-associated protein-1 UQ_con PF00179.26 CBZ31556.1 - 3.9e-10 39.5 0.0 7.6e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Peptidase_M28 PF04389.17 CBZ31558.1 - 1.3e-16 60.8 2.5 2.3e-05 24.2 0.3 3.8 4 0 0 4 4 4 3 Peptidase family M28 Peptidase_M49 PF03571.15 CBZ31559.1 - 3.8e-221 735.3 0.0 4.7e-221 734.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF1930 PF09122.10 CBZ31560.1 - 7.6e-39 131.6 0.1 1.4e-38 130.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1930) Rhodanese PF00581.20 CBZ31560.1 - 8.3e-14 52.0 0.0 1.5e-07 31.9 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Complex1_51K PF01512.17 CBZ31561.1 - 1.8e-45 154.5 0.0 3.5e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CBZ31561.1 - 1.2e-28 99.0 0.0 2.8e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CBZ31561.1 - 3.2e-08 33.3 0.0 6.5e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Ribosomal_S26e PF01283.19 CBZ31561.1 - 0.19 12.2 0.1 0.9 10.0 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S26e NDUF_B7 PF05676.13 CBZ31562.1 - 0.0034 17.1 1.4 0.005 16.5 1.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) zf-C2HC5 PF06221.13 CBZ31563.1 - 0.00055 19.9 3.8 0.00055 19.9 3.8 1.6 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type zf-C3HC4_3 PF13920.6 CBZ31563.1 - 0.00059 19.6 7.2 0.00096 19.0 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ31563.1 - 0.0069 16.3 7.1 0.013 15.5 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBZ31563.1 - 0.93 9.9 8.6 1.6 9.1 8.6 1.4 1 0 0 1 1 1 0 Ring finger domain TerY_C PF15616.6 CBZ31563.1 - 6.4 6.9 8.1 7.4 6.7 7.6 1.3 1 1 0 1 1 1 0 TerY-C metal binding domain UPF0020 PF01170.18 CBZ31564.1 - 1.2e-13 51.2 0.0 3.4e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CBZ31564.1 - 0.0021 17.8 0.0 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 DNA methylase N6_Mtase PF02384.16 CBZ31564.1 - 0.0022 17.4 0.0 0.0077 15.5 0.0 1.8 2 0 0 2 2 2 1 N-6 DNA Methylase Band_7 PF01145.25 CBZ31567.1 - 2e-25 89.8 1.0 2.8e-25 89.4 0.1 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CBZ31567.1 - 9.2e-22 76.9 1.6 1.4e-21 76.3 0.6 1.8 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 CBZ31567.1 - 0.016 14.9 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family KASH_CCD PF14662.6 CBZ31568.1 - 2 8.2 12.4 4.8 7.0 9.3 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH AFG1_ATPase PF03969.16 CBZ31569.1 - 5.9e-83 278.7 0.1 2.5e-76 257.0 0.0 3.0 1 1 1 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.6 CBZ31569.1 - 0.0038 17.5 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 CBZ31569.1 - 0.049 13.5 0.1 0.34 10.7 0.0 2.2 3 0 0 3 3 3 0 Bacterial dnaA protein ABC_tran PF00005.27 CBZ31569.1 - 0.092 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 CBZ31569.1 - 0.18 12.2 0.0 0.44 11.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Lectin_leg-like PF03388.13 CBZ31570.1 - 5.5e-12 45.5 0.0 3.2e-07 29.9 0.0 3.1 2 1 0 2 2 2 2 Legume-like lectin family YL1 PF05764.13 CBZ31570.1 - 2.2e-05 24.7 0.8 2.9e-05 24.3 0.8 1.2 1 0 0 1 1 1 1 YL1 nuclear protein THOC2_N PF16134.5 CBZ31570.1 - 0.26 9.9 1.2 0.37 9.4 1.2 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus ELH PF02323.15 CBZ31570.1 - 0.73 9.2 6.4 1.7 7.9 3.8 2.3 2 0 0 2 2 2 0 Egg-laying hormone precursor MORN PF02493.20 CBZ31571.1 - 4.4e-26 89.2 32.9 9e-08 31.6 1.8 7.1 7 0 0 7 7 7 5 MORN repeat Rad21_Rec8_N PF04825.13 CBZ31572.1 - 2.7e-28 98.3 0.1 5.3e-28 97.4 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CBZ31572.1 - 5.2e-08 32.0 0.4 6.6e-07 28.5 0.0 2.5 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 CBZ31572.1 - 0.092 12.6 0.1 16 5.3 0.0 2.2 2 0 0 2 2 2 0 Segregation and condensation protein ScpA Methyltransf_31 PF13847.6 CBZ31573.1 - 4.3e-10 39.6 0.0 5.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ31573.1 - 2.8e-09 37.6 0.0 1.5e-08 35.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ31573.1 - 3.4e-09 37.2 0.0 2e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ31573.1 - 2e-06 28.4 0.0 3.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CBZ31573.1 - 1.6e-05 24.9 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 2 Hypothetical methyltransferase TPMT PF05724.11 CBZ31573.1 - 3.2e-05 23.7 0.0 0.00076 19.2 0.0 2.2 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 CBZ31573.1 - 3.4e-05 23.5 0.0 6e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 CBZ31573.1 - 0.0038 16.6 0.0 0.026 13.9 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CBZ31573.1 - 0.006 16.6 0.0 0.0093 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.16 CBZ31573.1 - 0.0096 15.1 0.0 0.033 13.3 0.0 1.8 1 1 0 1 1 1 1 mRNA capping enzyme MTS PF05175.14 CBZ31573.1 - 0.013 15.0 0.0 0.049 13.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain EutQ PF06249.12 CBZ31573.1 - 0.045 13.5 0.0 0.076 12.8 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ CMAS PF02353.20 CBZ31573.1 - 0.047 13.0 0.0 0.08 12.2 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase RRM_1 PF00076.22 CBZ31574.1 - 4.2e-08 32.9 0.0 0.017 14.9 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YqfQ PF14181.6 CBZ31574.1 - 6.6 6.9 13.3 0.27 11.4 1.8 3.0 2 0 0 2 2 2 0 YqfQ-like protein DUF1869 PF08956.10 CBZ31576.1 - 0.15 12.0 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) vATP-synt_AC39 PF01992.16 CBZ31577.1 - 4.4e-87 292.7 0.7 5e-87 292.5 0.7 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit LRR_4 PF12799.7 CBZ31578.1 - 3.4e-10 40.0 2.1 0.043 14.3 0.0 5.9 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ31578.1 - 7.8e-06 25.6 5.4 2.5 7.9 0.0 5.6 6 0 0 6 6 6 2 Leucine rich repeat LRR_1 PF00560.33 CBZ31578.1 - 0.008 16.6 9.5 15 6.7 0.0 5.9 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 CBZ31578.1 - 0.0097 15.9 12.1 2.3 8.5 0.1 5.9 6 0 0 6 6 6 1 Leucine Rich repeat DUF641 PF04859.12 CBZ31578.1 - 0.2 12.0 6.9 0.41 11.0 6.9 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) HAUS-augmin3 PF14932.6 CBZ31578.1 - 0.46 10.0 7.1 1.1 8.8 7.1 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Jnk-SapK_ap_N PF09744.9 CBZ31578.1 - 0.53 10.5 7.6 0.91 9.7 7.6 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Filament PF00038.21 CBZ31578.1 - 0.69 9.4 8.9 1.1 8.8 8.9 1.1 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.11 CBZ31578.1 - 1.2 7.9 8.0 1.9 7.3 8.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.19 CBZ31578.1 - 2.3 8.0 12.6 4.3 7.1 12.6 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ELO PF01151.18 CBZ31579.1 - 1.6e-41 142.5 28.9 3e-41 141.6 28.9 1.4 1 1 0 1 1 1 1 GNS1/SUR4 family NDUFA12 PF05071.16 CBZ31580.1 - 0.011 16.6 0.2 0.048 14.5 0.2 2.2 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF346 PF03984.13 CBZ31580.1 - 0.035 13.9 5.4 0.18 11.6 2.9 2.6 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) Prefoldin_2 PF01920.20 CBZ31582.1 - 2.6e-18 65.9 3.7 2.6e-18 65.9 3.7 2.0 1 1 1 2 2 2 1 Prefoldin subunit DHR10 PF18595.1 CBZ31582.1 - 0.024 14.7 0.3 0.024 14.7 0.3 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain kleA_kleC PF17383.2 CBZ31582.1 - 0.032 14.6 2.4 0.067 13.5 2.4 1.5 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A PCRF PF03462.18 CBZ31582.1 - 0.22 11.4 5.1 0.24 11.3 0.0 2.0 1 1 1 2 2 2 0 PCRF domain FlaC_arch PF05377.11 CBZ31582.1 - 0.32 11.4 3.6 10 6.6 0.4 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Spc7 PF08317.11 CBZ31582.1 - 0.43 9.4 11.2 1.4 7.7 4.8 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein GPS2_interact PF15784.5 CBZ31582.1 - 0.71 10.3 8.5 0.079 13.4 4.2 1.7 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF724 PF05266.14 CBZ31582.1 - 1.1 9.1 7.2 2 8.2 3.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DASH_Spc19 PF08287.11 CBZ31582.1 - 1.2 9.0 12.2 0.47 10.3 4.7 2.1 1 1 1 2 2 2 0 Spc19 OmpH PF03938.14 CBZ31582.1 - 1.5 9.2 15.4 0.69 10.2 10.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 CBZ31582.1 - 2.4 8.4 9.7 11 6.3 4.2 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Osmo_CC PF08946.10 CBZ31582.1 - 6 7.2 13.7 35 4.7 7.8 3.6 2 2 0 2 2 2 0 Osmosensory transporter coiled coil LRR_4 PF12799.7 CBZ31583.1 - 2.8e-24 84.8 25.9 0.00011 22.5 0.1 7.3 3 3 6 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ31583.1 - 1.1e-22 79.6 38.0 4.8e-08 32.7 5.9 6.5 3 2 5 8 8 8 7 Leucine rich repeat LRR_9 PF14580.6 CBZ31583.1 - 8.6e-20 71.0 4.3 4.5e-08 32.8 0.1 3.2 2 1 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CBZ31583.1 - 5.4e-06 26.0 17.2 0.97 9.7 0.0 8.5 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 CBZ31583.1 - 0.047 14.2 21.9 16 6.5 0.1 8.8 9 1 1 10 10 10 0 Leucine Rich Repeat Chlorovi_GP_rpt PF06598.11 CBZ31584.1 - 0.015 15.3 1.7 3.4 7.8 0.0 3.3 3 0 0 3 3 3 0 Chlorovirus glycoprotein repeat LRR_4 PF12799.7 CBZ31584.1 - 0.062 13.7 0.0 13 6.4 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) CENP-T_C PF15511.6 CBZ31585.1 - 3.1e-06 27.3 0.1 5.2e-06 26.5 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBZ31585.1 - 5.5e-05 23.4 0.6 8.8e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CBZ31585.1 - 0.00015 21.8 0.1 0.00026 21.1 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CBZ31585.1 - 0.00056 20.3 2.9 0.0012 19.3 2.9 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CBZ31585.1 - 0.0018 18.2 0.0 0.0024 17.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 CBZ31585.1 - 0.028 14.5 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ly-6_related PF06579.12 CBZ31585.1 - 0.068 13.4 0.5 0.084 13.1 0.5 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein PCP_red PF08369.10 CBZ31585.1 - 0.14 12.4 0.7 0.35 11.1 0.2 2.0 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit LRR_4 PF12799.7 CBZ31586.1 - 7.4e-18 64.4 3.0 0.008 16.6 1.4 8.5 3 1 9 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ31586.1 - 0.00042 20.0 16.0 6.5 6.6 0.2 6.9 4 1 4 8 8 8 4 Leucine rich repeat LRR_9 PF14580.6 CBZ31586.1 - 0.0011 18.5 4.4 1.2 8.6 0.1 4.0 2 1 2 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 CBZ31586.1 - 0.0055 16.7 19.4 0.75 10.0 0.0 10.0 13 0 0 13 13 13 1 Leucine Rich repeat WD40 PF00400.32 CBZ31587.1 - 1.7e-48 161.6 25.6 2.3e-09 37.7 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ31587.1 - 9.4e-08 32.3 0.4 0.0011 19.2 0.0 4.2 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBZ31587.1 - 9.2e-05 21.9 0.2 0.18 11.1 0.0 2.8 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 CBZ31587.1 - 0.0096 14.6 10.3 0.041 12.5 0.3 4.2 1 1 2 4 4 4 1 Nucleoporin Nup120/160 DUF1137 PF06587.11 CBZ31587.1 - 0.023 14.7 0.3 7.8 6.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1137) PB1 PF00564.24 CBZ31587.1 - 0.049 13.6 0.0 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 PB1 domain FKBP_N PF01346.18 CBZ31587.1 - 0.075 14.0 1.6 8.7 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase MRP-L46 PF11788.8 CBZ31588.1 - 1.5e-15 57.9 0.0 3.9e-15 56.6 0.0 1.7 1 1 0 1 1 1 1 39S mitochondrial ribosomal protein L46 PUF PF00806.19 CBZ31589.1 - 9e-24 81.8 7.4 2.6e-05 23.6 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat PAP1 PF08601.10 CBZ31589.1 - 8.1 6.1 9.0 11 5.6 9.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 bZIP_1 PF00170.21 CBZ31590.1 - 0.00048 20.2 8.0 0.0034 17.4 0.4 3.4 3 0 0 3 3 3 1 bZIP transcription factor HTH_5 PF01022.20 CBZ31590.1 - 0.014 15.3 6.2 0.36 10.7 0.0 3.5 4 0 0 4 4 4 0 Bacterial regulatory protein, arsR family BLACT_WH PF17778.1 CBZ31590.1 - 0.017 15.1 1.1 0.03 14.3 0.1 2.0 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain TolA_bind_tri PF16331.5 CBZ31590.1 - 0.043 13.9 5.9 4.2 7.5 0.3 3.5 3 0 0 3 3 3 0 TolA binding protein trimerisation PhaP_Bmeg PF09602.10 CBZ31590.1 - 0.2 11.6 7.8 0.8 9.6 0.1 2.9 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DMPK_coil PF08826.10 CBZ31590.1 - 1.3 9.2 10.1 0.51 10.5 0.2 3.3 3 0 0 3 3 3 0 DMPK coiled coil domain like FlaC_arch PF05377.11 CBZ31590.1 - 3.1 8.3 6.0 1.5 9.3 0.2 3.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 CBZ31590.1 - 3.9 7.3 14.5 0.42 10.4 0.8 3.7 2 1 2 4 4 4 0 Septum formation initiator Ntox23 PF15528.6 CBZ31591.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 23 ABC_tran PF00005.27 CBZ31592.1 - 7.7e-06 26.5 0.4 7.7e-06 26.5 0.4 1.7 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 CBZ31592.1 - 0.00069 20.2 0.2 0.0012 19.4 0.1 1.4 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 CBZ31592.1 - 0.00083 19.3 0.1 0.0011 18.9 0.1 1.2 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 CBZ31592.1 - 0.001 19.0 0.1 0.0013 18.6 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase DUF87 PF01935.17 CBZ31592.1 - 0.0015 18.7 0.3 0.0023 18.1 0.3 1.3 1 0 0 1 1 1 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 CBZ31592.1 - 0.0064 16.6 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.6 CBZ31592.1 - 0.0081 16.5 0.1 0.012 16.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CBZ31592.1 - 0.012 15.4 1.0 0.016 14.9 0.3 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CBZ31592.1 - 0.027 14.8 0.4 0.041 14.3 0.4 1.3 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 CBZ31592.1 - 0.037 13.6 0.1 0.058 13.0 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 CBZ31592.1 - 0.039 13.9 0.1 0.06 13.4 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CBZ31592.1 - 0.057 13.7 0.1 0.088 13.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 CBZ31592.1 - 0.064 12.7 0.0 0.099 12.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein PRK PF00485.18 CBZ31592.1 - 0.07 12.9 0.1 0.095 12.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 CBZ31592.1 - 0.074 13.4 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MobB PF03205.14 CBZ31592.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 CBZ31592.1 - 0.089 12.1 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 CBZ31592.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 CBZ31592.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CBZ31592.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Dynamin family T2SSE PF00437.20 CBZ31592.1 - 0.16 11.0 0.1 0.19 10.8 0.1 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.18 CBZ31592.1 - 0.18 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_30 PF13604.6 CBZ31592.1 - 0.2 11.4 0.1 0.27 10.9 0.1 1.2 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CBZ31592.1 - 0.2 11.9 0.0 0.37 11.0 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF463 PF04317.12 CBZ31592.1 - 0.27 10.1 0.1 0.37 9.7 0.1 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 ABC_tran PF00005.27 CBZ31593.1 - 2.8e-06 27.9 0.0 3.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 CBZ31593.1 - 0.00045 20.8 0.0 0.00062 20.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CBZ31593.1 - 0.001 19.0 0.1 0.0014 18.6 0.1 1.2 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 CBZ31593.1 - 0.0013 18.6 0.1 0.0017 18.3 0.1 1.1 1 0 0 1 1 1 1 RsgA GTPase DUF87 PF01935.17 CBZ31593.1 - 0.0022 18.1 0.3 0.0028 17.8 0.3 1.1 1 0 0 1 1 1 1 Helicase HerA, central domain MMR_HSR1 PF01926.23 CBZ31593.1 - 0.0073 16.4 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.6 CBZ31593.1 - 0.0096 16.3 0.0 0.013 15.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CBZ31593.1 - 0.012 15.3 0.3 0.02 14.6 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CBZ31593.1 - 0.028 14.8 0.1 0.038 14.4 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 CBZ31593.1 - 0.048 13.7 0.2 0.072 13.1 0.2 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 CBZ31593.1 - 0.052 13.1 0.1 0.069 12.7 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CBZ31593.1 - 0.061 13.6 0.1 0.093 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 CBZ31593.1 - 0.074 12.8 0.1 0.094 12.4 0.1 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 CBZ31593.1 - 0.08 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.12 CBZ31593.1 - 0.084 12.3 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein MobB PF03205.14 CBZ31593.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 CBZ31593.1 - 0.11 11.8 0.1 0.14 11.5 0.1 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 CBZ31593.1 - 0.13 12.0 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CBZ31593.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 NTPase Dynamin_N PF00350.23 CBZ31593.1 - 0.17 12.0 0.1 0.24 11.5 0.1 1.2 1 0 0 1 1 1 0 Dynamin family T2SSE PF00437.20 CBZ31593.1 - 0.18 10.8 0.1 0.25 10.4 0.1 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.18 CBZ31593.1 - 0.2 10.9 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_30 PF13604.6 CBZ31593.1 - 0.24 11.1 0.1 0.32 10.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CBZ31593.1 - 0.26 11.5 0.0 0.41 10.9 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF463 PF04317.12 CBZ31593.1 - 0.27 10.1 0.0 0.36 9.7 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 CytochromB561_N PF09786.9 CBZ31595.1 - 1e-05 24.8 0.0 2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome B561, N terminal Pro_isomerase PF00160.21 CBZ31596.1 - 5.6e-51 172.9 0.1 6.4e-51 172.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1768 PF08719.11 CBZ31597.1 - 1.3e-24 87.2 0.0 1.6e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Proteasome PF00227.26 CBZ31598.1 - 7.1e-31 107.2 0.0 9.7e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Cation_ATPase_C PF00689.21 CBZ31599.1 - 0.17 11.6 0.0 0.21 11.3 0.0 1.1 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus HD PF01966.22 CBZ31600.1 - 6e-14 52.3 0.3 6e-14 52.3 0.3 1.9 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 CBZ31600.1 - 0.00035 20.4 0.0 0.00068 19.4 0.0 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HDOD PF08668.12 CBZ31600.1 - 0.00042 19.8 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 HDOD domain Trm112p PF03966.16 CBZ31601.1 - 1.6e-07 31.8 0.0 5.8e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 Trm112p-like protein zinc_ribbon_4 PF13717.6 CBZ31601.1 - 0.051 13.5 2.0 0.052 13.5 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 CBZ31601.1 - 0.37 10.6 0.3 0.37 10.6 0.3 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Kinesin PF00225.23 CBZ31602.1 - 1.4e-70 237.9 0.0 1.9e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ31602.1 - 1.3e-10 41.4 0.0 9.5e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 Microtubule binding FHA PF00498.26 CBZ31605.1 - 1.3e-09 38.3 0.0 9.8e-09 35.4 0.0 2.3 1 1 0 1 1 1 1 FHA domain DUF4490 PF14892.6 CBZ31606.1 - 0.00015 21.7 0.2 0.00028 20.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) Leu_zip PF15294.6 CBZ31609.1 - 4.8e-12 46.0 13.5 7.2e-06 25.7 3.0 2.4 1 1 1 2 2 2 2 Leucine zipper V-ATPase_G_2 PF16999.5 CBZ31609.1 - 0.00089 19.6 0.7 0.00089 19.6 0.7 2.6 3 0 0 3 3 3 1 Vacuolar (H+)-ATPase G subunit FAM184 PF15665.5 CBZ31609.1 - 0.013 15.3 9.0 0.021 14.6 9.0 1.3 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF4936 PF16290.5 CBZ31609.1 - 0.042 14.5 8.1 0.14 12.9 1.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4936) ZapB PF06005.12 CBZ31609.1 - 0.15 12.6 12.1 0.19 12.2 4.5 2.5 2 0 0 2 2 2 0 Cell division protein ZapB FAM76 PF16046.5 CBZ31609.1 - 0.31 10.4 3.5 0.46 9.8 3.5 1.2 1 0 0 1 1 1 0 FAM76 protein DUF848 PF05852.11 CBZ31609.1 - 0.9 9.6 6.1 0.78 9.9 4.0 2.1 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) TMF_TATA_bd PF12325.8 CBZ31609.1 - 2.1 8.6 14.9 2.8 8.2 2.7 2.5 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 CBZ31609.1 - 2.2 8.4 8.7 1.7 8.7 0.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF1104 PF06518.11 CBZ31609.1 - 3.3 8.1 6.8 1.8 9.0 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) GAS PF13851.6 CBZ31609.1 - 3.5 6.9 14.3 2.7 7.3 7.0 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 CBZ31609.1 - 4.2 6.8 13.9 4.4 6.8 13.3 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit UPF0449 PF15136.6 CBZ31609.1 - 8 7.0 9.9 0.62 10.6 1.6 2.8 2 1 0 3 3 3 0 Uncharacterised protein family UPF0449 DivIVA PF05103.13 CBZ31609.1 - 9.8 6.3 12.0 0.63 10.1 0.8 3.1 1 1 1 2 2 2 0 DivIVA protein XRN_N PF03159.18 CBZ31610.1 - 2.2e-90 302.3 0.0 3.7e-90 301.6 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CBZ31610.1 - 3.2e-83 280.2 6.9 1.2e-54 186.0 1.8 2.6 2 1 1 3 3 3 2 Xrn1 helical domain XRN1_D1 PF18332.1 CBZ31610.1 - 5.2e-24 85.1 0.1 8.5e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 CBZ31610.1 - 2.4e-16 59.6 0.2 1.2e-15 57.4 0.0 2.2 2 0 0 2 2 2 1 Xrn1 SH3-like domain FHA PF00498.26 CBZ31612.1 - 0.015 15.6 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 FHA domain Yop-YscD_cpl PF16697.5 CBZ31612.1 - 0.018 15.4 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain RNase_H PF00075.24 CBZ31613.1 - 1.9e-28 99.5 0.5 3.7e-20 72.6 0.0 2.9 1 1 1 2 2 2 2 RNase H NDUF_B6 PF09782.9 CBZ31613.1 - 0.18 11.9 0.6 0.27 11.3 0.6 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit zf-MYND PF01753.18 CBZ31614.1 - 4.1e-12 46.0 14.5 4.1e-12 46.0 14.5 1.9 2 0 0 2 2 2 1 MYND finger DUF4599 PF15371.6 CBZ31614.1 - 0.2 12.2 4.1 2.7 8.6 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4599) zf-Mss51 PF13824.6 CBZ31614.1 - 0.41 10.8 6.4 0.98 9.6 6.4 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.16 CBZ31614.1 - 6.2 6.8 19.8 0.17 11.8 6.9 2.8 3 0 0 3 3 3 0 HIT zinc finger BT1 PF03092.16 CBZ31615.1 - 3.4e-193 642.6 8.2 4e-193 642.4 8.2 1.0 1 0 0 1 1 1 1 BT1 family SAM_LFY PF01698.16 CBZ31615.1 - 0.051 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein SAM domain Lamprin PF06403.11 CBZ31615.1 - 0.13 12.3 0.9 0.27 11.2 0.9 1.5 1 0 0 1 1 1 0 Lamprin TPR_2 PF07719.17 CBZ31617.1 - 0.0009 19.2 9.9 0.85 9.9 1.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat GOLGA2L5 PF15070.6 CBZ31617.1 - 0.0088 14.8 6.4 0.013 14.2 6.4 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 TPR_16 PF13432.6 CBZ31617.1 - 0.018 15.7 4.9 0.018 15.7 4.9 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.12 CBZ31617.1 - 0.39 11.5 5.1 0.38 11.5 0.2 2.5 2 0 0 2 2 2 0 Sel1 repeat TPR_1 PF00515.28 CBZ31617.1 - 0.47 10.4 4.3 2.4 8.1 0.5 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ31617.1 - 1.9 9.5 19.9 4.3 8.4 1.1 5.1 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF5446 PF17522.2 CBZ31617.1 - 8.2 6.7 9.7 0.59 10.3 4.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Peptidase_S9 PF00326.21 CBZ31618.1 - 6e-32 110.8 0.0 1.1e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 CBZ31618.1 - 4.4e-27 94.9 0.0 8.1e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain 3Beta_HSD PF01073.19 CBZ31619.1 - 5.5e-37 127.3 0.0 7e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CBZ31619.1 - 3.3e-26 92.2 0.0 4.3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBZ31619.1 - 2.3e-15 56.9 0.0 3.3e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CBZ31619.1 - 9.7e-15 54.4 0.0 5.9e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 CBZ31619.1 - 2.9e-12 46.6 0.0 4.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CBZ31619.1 - 1.6e-08 34.0 0.0 2.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CBZ31619.1 - 1.9e-08 33.8 0.0 3.4e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CBZ31619.1 - 3.7e-06 26.7 0.0 5.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 CBZ31619.1 - 0.002 17.6 0.1 0.0062 16.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CBZ31619.1 - 0.0023 17.9 0.2 0.0086 16.0 0.2 1.9 2 1 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 CBZ31619.1 - 0.083 13.2 0.1 0.41 10.9 0.1 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Gln-synt_C PF00120.24 CBZ31621.1 - 1.5e-18 67.0 0.0 5.3e-18 65.1 0.0 1.8 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CBZ31621.1 - 9.3e-14 50.9 0.0 1.8e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Lipoprotein_21 PF14041.6 CBZ31621.1 - 0.78 9.9 2.5 0.41 10.8 0.1 1.7 2 0 0 2 2 2 0 LppP/LprE lipoprotein zf_CCCH_4 PF18345.1 CBZ31622.1 - 1.3e-06 28.3 2.6 2.8e-06 27.2 2.6 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CBZ31622.1 - 4.1e-06 26.6 1.7 8.6e-06 25.5 1.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ31622.1 - 5.4e-06 26.1 0.7 1e-05 25.2 0.7 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CBZ31622.1 - 0.00054 20.6 0.1 0.0013 19.4 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CBZ31622.1 - 0.067 13.7 1.4 0.067 13.7 1.4 1.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger LRR_6 PF13516.6 CBZ31622.1 - 0.14 12.3 0.0 3.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Leucine Rich repeat Ribosomal_L19e PF01280.20 CBZ31625.1 - 1.7e-59 200.0 10.8 1.7e-59 200.0 10.8 2.1 2 0 0 2 2 2 1 Ribosomal protein L19e Rrn6 PF10214.9 CBZ31625.1 - 0.19 10.2 6.9 0.24 9.8 6.9 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF2981 PF11200.8 CBZ31625.1 - 3.7 7.2 4.4 5.1 6.7 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Kinesin PF00225.23 CBZ31628.1 - 1.9e-09 36.9 4.5 0.0005 19.1 0.0 3.1 3 0 0 3 3 3 2 Kinesin motor domain AAA_13 PF13166.6 CBZ31628.1 - 0.033 12.8 6.7 0.051 12.2 6.7 1.2 1 0 0 1 1 1 0 AAA domain SCAB_CC PF16712.5 CBZ31628.1 - 0.071 12.9 13.1 0.039 13.8 9.1 2.2 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein TMF_DNA_bd PF12329.8 CBZ31628.1 - 0.15 12.0 12.4 0.054 13.5 8.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MCPsignal PF00015.21 CBZ31628.1 - 0.6 9.9 16.5 0.7 9.7 7.4 3.2 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 CBZ31628.1 - 0.94 9.8 3.3 4.6 7.6 0.2 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 CBZ31628.1 - 1.4 8.9 11.0 0.17 12.0 1.8 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF913 PF06025.12 CBZ31628.1 - 1.7 7.5 9.1 2.9 6.8 7.5 2.1 2 1 0 2 2 2 0 Domain of Unknown Function (DUF913) UPF0231 PF06062.11 CBZ31628.1 - 2 8.7 7.5 1.5 9.1 0.3 2.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0231) DUF2730 PF10805.8 CBZ31628.1 - 2.1 8.5 7.3 0.56 10.3 3.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.19 CBZ31628.1 - 6.1 4.6 7.6 8.8 4.1 7.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TPR_12 PF13424.6 CBZ31629.1 - 2e-06 28.0 0.3 0.002 18.4 0.2 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ31629.1 - 7.1e-06 25.7 0.5 0.042 13.7 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ31629.1 - 0.00065 19.4 2.0 0.034 14.0 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ31629.1 - 0.0065 16.5 0.0 0.052 13.7 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ31629.1 - 0.041 13.9 0.0 7.1 6.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ31629.1 - 0.05 14.1 2.4 0.15 12.6 0.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpF PF06266.12 CBZ31629.1 - 0.17 12.2 1.3 0.57 10.5 0.1 2.5 2 1 0 2 2 2 0 HrpF protein NAD_kinase PF01513.21 CBZ31631.1 - 7.1e-10 38.6 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase Cnd2 PF05786.14 CBZ31632.1 - 2.2e-25 89.5 11.2 3.7e-18 65.6 0.1 3.5 3 1 0 3 3 3 2 Condensin complex subunit 2 CNDH2_N PF06278.11 CBZ31632.1 - 0.015 15.5 0.0 0.067 13.4 0.0 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal SpoU_methylase PF00588.19 CBZ31635.1 - 2e-15 57.2 0.0 5.1e-09 36.4 0.0 3.1 3 0 0 3 3 3 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CBZ31635.1 - 1.2e-05 25.5 0.0 0.00015 22.0 0.0 2.3 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding U-box PF04564.15 CBZ31636.1 - 3.3e-12 46.4 0.0 6.8e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 CBZ31636.1 - 0.14 12.4 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein LRR_4 PF12799.7 CBZ31637.1 - 5.6e-13 48.9 3.9 0.097 13.1 0.1 9.2 8 3 2 11 11 11 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ31637.1 - 1.4e-06 27.9 2.4 1.9 8.3 0.2 6.9 7 0 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.6 CBZ31637.1 - 0.0056 16.6 9.6 42 4.6 0.0 7.3 10 0 0 10 10 10 3 Leucine Rich repeat PDT PF00800.18 CBZ31638.1 - 0.067 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydratase Maf_N PF08383.11 CBZ31638.1 - 0.2 11.4 0.1 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 Maf N-terminal region dUTPase_2 PF08761.11 CBZ31641.1 - 2.3e-46 158.0 0.0 3.4e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 dUTPase Ribosomal_L23 PF00276.20 CBZ31642.1 - 6e-16 58.6 3.4 6e-16 58.6 3.4 2.4 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CBZ31642.1 - 0.0023 18.1 8.8 0.0023 18.1 8.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain TusA PF01206.17 CBZ31642.1 - 0.0097 15.7 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 1 Sulfurtransferase TusA Ribosomal_L23 PF00276.20 CBZ31643.1 - 6e-16 58.6 3.4 6e-16 58.6 3.4 2.4 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 CBZ31643.1 - 0.0023 18.1 8.8 0.0023 18.1 8.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain TusA PF01206.17 CBZ31643.1 - 0.0097 15.7 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 1 Sulfurtransferase TusA PHD PF00628.29 CBZ31645.1 - 8.2e-05 22.4 1.0 8.2e-05 22.4 1.0 2.0 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 CBZ31645.1 - 0.19 11.3 0.9 0.38 10.3 0.9 1.5 1 0 0 1 1 1 0 PHD-finger Pro_CA PF00484.19 CBZ31646.1 - 1.3e-42 145.7 2.1 4.9e-41 140.6 2.1 2.1 1 1 0 1 1 1 1 Carbonic anhydrase DUF89 PF01937.19 CBZ31647.1 - 7.3e-41 140.3 0.1 2.4e-21 76.1 0.0 4.5 4 0 0 4 4 4 4 Protein of unknown function DUF89 Put_Phosphatase PF06888.12 CBZ31647.1 - 2e-33 115.8 2.1 1.3e-14 54.2 0.1 3.3 3 0 0 3 3 3 3 Putative Phosphatase HAD PF12710.7 CBZ31647.1 - 0.0062 17.0 3.2 0.12 12.8 0.1 3.6 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 CBZ31649.1 - 2.3e-46 158.3 0.0 3.5e-45 154.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31649.1 - 8.7e-31 107.1 0.0 1.4e-22 80.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 CBZ31649.1 - 7e-09 35.9 0.1 1.5e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 FHA domain PAS PF00989.25 CBZ31649.1 - 0.0016 18.4 0.0 0.21 11.6 0.0 2.6 2 0 0 2 2 2 1 PAS fold Kinase-like PF14531.6 CBZ31649.1 - 0.0035 16.7 0.0 0.0075 15.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ31649.1 - 0.065 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBZ31649.1 - 0.22 10.9 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SQHop_cyclase_N PF13249.6 CBZ31650.1 - 5.5e-47 160.3 0.3 1.1e-43 149.5 0.1 3.2 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CBZ31650.1 - 3.3e-37 128.3 1.6 1.4e-32 113.1 0.7 2.9 3 0 0 3 3 3 2 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 CBZ31650.1 - 1.1e-23 82.7 16.4 2.5e-09 36.7 0.0 6.1 6 1 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 CBZ31650.1 - 0.0054 16.1 0.1 4.4 6.5 0.0 3.6 3 1 1 4 4 4 2 Pectic acid lyase NDUF_B7 PF05676.13 CBZ31653.1 - 5.9e-05 22.7 3.7 0.00011 21.9 3.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 CBZ31653.1 - 0.0017 18.3 4.7 0.003 17.5 4.7 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 CBZ31653.1 - 0.19 12.0 2.8 0.37 11.1 2.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 CBZ31653.1 - 1.3 9.3 4.8 2.2 8.5 4.8 1.5 1 0 0 1 1 1 0 CHCH domain Ctf8 PF09696.10 CBZ31654.1 - 6.3e-10 39.5 0.0 0.00013 22.4 0.0 3.2 3 0 0 3 3 3 3 Ctf8 DUF1908 PF08926.11 CBZ31654.1 - 9.9 5.1 6.9 19 4.2 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) C2 PF00168.30 CBZ31656.1 - 3.4e-09 36.9 0.0 5.6e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain Ank_2 PF12796.7 CBZ31656.1 - 1.2e-07 32.2 0.0 8.6e-07 29.5 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ31656.1 - 1.3e-06 28.8 0.1 0.0074 16.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ31656.1 - 2.4e-06 27.7 0.4 0.04 14.3 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ31656.1 - 3.6e-06 27.2 0.2 0.063 13.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CBZ31656.1 - 0.025 15.1 0.3 16 6.5 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat YEATS PF03366.16 CBZ31658.1 - 3e-15 55.9 0.0 5.3e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 YEATS family SDA1 PF05285.12 CBZ31658.1 - 0.0075 15.7 6.6 0.015 14.8 6.6 1.5 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 CBZ31658.1 - 7.9 4.5 9.3 12 3.9 9.3 1.2 1 0 0 1 1 1 0 Nop14-like family PALP PF00291.25 CBZ31659.1 - 3e-57 194.3 0.5 3.4e-57 194.1 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HlyIII PF03006.20 CBZ31661.1 - 9.7e-14 51.6 17.4 1.6e-06 28.0 13.6 3.0 2 1 0 2 2 2 2 Haemolysin-III related RRM_1 PF00076.22 CBZ31663.1 - 4.9e-25 87.1 0.0 5.6e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ31663.1 - 0.05 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 CBZ31663.1 - 0.074 13.3 0.0 12 6.0 0.0 2.8 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Glyoxalase PF00903.25 CBZ31668.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pil1 PF13805.6 CBZ31668.1 - 0.019 14.4 8.4 0.44 10.0 0.9 2.4 2 0 0 2 2 2 0 Eisosome component PIL1 DUF4618 PF15397.6 CBZ31668.1 - 0.026 14.0 2.2 2.1 7.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Spc24 PF08286.11 CBZ31668.1 - 0.3 11.4 2.1 2.9 8.2 0.2 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 IFT57 PF10498.9 CBZ31668.1 - 0.77 8.7 5.6 0.51 9.3 0.4 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF2721 PF11026.8 CBZ31668.1 - 1.6 8.7 9.6 0.38 10.7 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) ADIP PF11559.8 CBZ31668.1 - 2.8 8.0 15.3 0.74 9.9 0.2 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding YlqD PF11068.8 CBZ31668.1 - 2.8 8.3 8.9 5.2 7.4 0.7 2.8 3 0 0 3 3 3 0 YlqD protein GrpE PF01025.19 CBZ31668.1 - 4.6 6.9 7.4 5.9 6.5 0.3 2.7 3 0 0 3 3 3 0 GrpE T3SSipB PF16535.5 CBZ31668.1 - 5.6 7.4 17.8 0.11 13.0 1.5 3.1 3 0 0 3 3 3 0 Type III cell invasion protein SipB LNS2 PF08235.13 CBZ31669.1 - 2.3e-82 275.8 0.0 3.2e-82 275.4 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CBZ31669.1 - 9.9e-18 64.0 0.0 2.1e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 CBZ31669.1 - 0.05 13.2 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PLCC PF14466.6 CBZ31670.1 - 0.057 13.6 0.4 0.4 10.8 0.1 2.1 2 1 0 2 2 2 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein EF-hand_1 PF00036.32 CBZ31671.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 EF hand SfLAP PF11139.8 CBZ31671.1 - 0.086 12.3 2.2 0.28 10.6 0.1 2.4 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein EF-hand_7 PF13499.6 CBZ31671.1 - 0.14 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Thymidylat_synt PF00303.19 CBZ31672.1 - 4.9e-109 363.6 0.0 6.4e-109 363.2 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 CBZ31672.1 - 9.7e-25 87.1 0.0 5e-24 84.8 0.0 2.2 1 1 0 1 1 1 1 Dihydrofolate reductase Spo12 PF05032.12 CBZ31672.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Spo12 family PrmA PF06325.13 CBZ31673.1 - 3.8e-09 36.4 0.0 7.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CBZ31673.1 - 4.3e-06 27.3 0.0 1.2e-05 26.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CBZ31673.1 - 1.3e-05 25.1 0.0 2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Cons_hypoth95 PF03602.15 CBZ31673.1 - 4.6e-05 23.2 0.0 7.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 CBZ31673.1 - 0.0001 21.9 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 CBZ31673.1 - 0.0004 20.2 0.0 0.00076 19.3 0.0 1.5 2 0 0 2 2 2 1 Met-10+ like-protein PCMT PF01135.19 CBZ31673.1 - 0.00073 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 CBZ31673.1 - 0.0025 16.9 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 CBZ31673.1 - 0.0029 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CBZ31673.1 - 0.0097 16.5 0.0 0.025 15.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ31673.1 - 0.014 16.1 0.0 0.043 14.6 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 CBZ31673.1 - 0.036 14.0 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 CBZ31673.1 - 0.081 14.0 0.0 0.45 11.6 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ31673.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Acyl-CoA_dh_1 PF00441.24 CBZ31674.1 - 3.6e-48 163.6 3.1 5.9e-48 162.9 3.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBZ31674.1 - 4e-27 95.1 0.2 1.1e-26 93.6 0.2 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBZ31674.1 - 2.1e-26 91.9 1.1 3.8e-26 91.1 0.3 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBZ31674.1 - 8e-21 74.7 1.2 1.3e-20 74.1 1.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CBZ31674.1 - 0.00058 19.6 0.5 0.0033 17.1 0.5 2.2 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal PP2C PF00481.21 CBZ31676.1 - 1.3e-23 84.0 0.9 6e-16 58.8 0.0 3.6 4 0 0 4 4 4 3 Protein phosphatase 2C SpoIIE PF07228.12 CBZ31676.1 - 0.03 14.2 0.2 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PTH2 PF01981.16 CBZ31677.1 - 5.8e-46 155.6 0.3 6.5e-46 155.4 0.3 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Oxidored_FMN PF00724.20 CBZ31679.1 - 3.3e-41 141.7 0.0 4.4e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 CBZ31679.1 - 6.1e-16 58.5 0.0 2.1e-15 56.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ31679.1 - 2.9e-10 40.2 0.0 1.1e-09 38.3 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CBZ31679.1 - 1.4e-07 32.0 0.6 0.00043 20.8 0.5 3.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBZ31679.1 - 1.9e-07 30.5 0.0 3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CBZ31679.1 - 7.8e-07 28.8 0.1 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CBZ31679.1 - 1.8e-06 27.0 1.4 5.6e-06 25.3 0.1 2.3 2 1 1 3 3 3 1 HI0933-like protein DAO PF01266.24 CBZ31679.1 - 2.3e-06 27.5 0.5 5.2e-06 26.3 0.5 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBZ31679.1 - 0.0011 18.4 0.4 0.0088 15.3 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBZ31679.1 - 0.0011 18.1 0.2 0.0017 17.5 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 CBZ31679.1 - 0.0031 16.9 0.1 0.005 16.2 0.1 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 CBZ31679.1 - 0.0038 16.5 0.0 0.0078 15.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 CBZ31679.1 - 0.0089 15.3 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 CBZ31679.1 - 0.02 14.6 0.3 0.075 12.7 0.3 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 CBZ31679.1 - 0.026 14.9 0.2 0.73 10.3 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 CBZ31679.1 - 0.037 13.9 0.0 0.096 12.6 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 CBZ31679.1 - 0.059 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.6 CBZ31679.1 - 0.083 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 CBZ31679.1 - 0.16 12.1 0.0 26 4.9 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TLD PF07534.16 CBZ31680.1 - 4.3e-08 33.5 0.0 9.2e-05 22.7 0.0 3.2 3 0 0 3 3 3 3 TLD SIS PF01380.22 CBZ31681.1 - 3.9e-48 162.6 4.5 1.8e-27 95.8 0.1 2.6 3 0 0 3 3 3 2 SIS domain GATase_6 PF13522.6 CBZ31681.1 - 6.7e-16 58.7 0.0 1.6e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CBZ31681.1 - 6.1e-09 35.8 0.0 1.4e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CBZ31681.1 - 0.0031 16.5 0.0 0.006 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 CBZ31681.1 - 0.011 15.8 0.1 0.62 10.1 0.0 2.6 2 1 0 2 2 2 0 SIS domain DUF2529 PF10740.9 CBZ31681.1 - 0.013 15.2 0.1 0.041 13.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) Cas_APE2256 PF09651.10 CBZ31681.1 - 0.13 12.2 0.1 0.78 9.6 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) Mob1_phocein PF03637.17 CBZ31682.1 - 1.1e-69 233.8 0.2 1.4e-69 233.4 0.2 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF3883 PF13020.6 CBZ31683.1 - 1.7e-15 56.8 0.0 3.4e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) LRR_8 PF13855.6 CBZ31684.1 - 1.1e-23 82.8 12.7 3.2e-08 33.2 0.7 4.9 5 0 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CBZ31684.1 - 4.6e-15 55.5 12.9 0.021 15.2 0.0 6.8 5 2 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ31684.1 - 2.3e-07 30.4 13.9 8 7.4 0.1 10.6 11 1 0 11 11 11 1 Leucine Rich Repeat LRR_9 PF14580.6 CBZ31684.1 - 0.0014 18.1 2.4 0.53 9.8 0.4 3.8 4 1 0 4 4 4 1 Leucine-rich repeat GRDP-like PF07173.12 CBZ31684.1 - 0.0081 16.8 3.3 5.5 7.6 0.1 4.1 3 1 1 4 4 4 1 Glycine-rich domain-containing protein-like LRR_6 PF13516.6 CBZ31684.1 - 0.044 13.8 20.1 14 6.0 0.0 8.8 10 0 0 10 10 10 0 Leucine Rich repeat DUF3024 PF11225.8 CBZ31684.1 - 1.3 9.4 3.7 0.37 11.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) WD40 PF00400.32 CBZ31685.1 - 0.1 13.5 0.5 39 5.3 0.1 3.3 2 0 0 2 2 2 0 WD domain, G-beta repeat SET PF00856.28 CBZ31687.1 - 4.2e-17 63.1 0.0 7.7e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 CBZ31687.1 - 8.7e-05 22.5 10.8 8.7e-05 22.5 10.8 3.1 3 1 0 3 3 3 1 MYND finger GTP_cyclohydroI PF01227.22 CBZ31687.1 - 0.14 11.6 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 GTP cyclohydrolase I G-patch PF01585.23 CBZ31689.1 - 3.9e-11 42.7 2.0 6.6e-11 41.9 2.0 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBZ31689.1 - 1.3e-07 31.6 1.2 3.6e-07 30.2 1.2 1.7 1 0 0 1 1 1 1 G-patch domain Kinesin PF00225.23 CBZ31690.1 - 1.6e-62 211.4 0.0 2.9e-62 210.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ31690.1 - 5.7e-12 45.8 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 CBZ31690.1 - 0.0026 18.2 0.1 0.011 16.2 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 CBZ31690.1 - 0.038 13.5 0.1 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 CBZ31690.1 - 0.099 12.9 0.1 0.33 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain OmpH PF03938.14 CBZ31690.1 - 0.14 12.5 4.5 1.7 9.0 0.2 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF87 PF01935.17 CBZ31690.1 - 0.19 11.8 0.1 0.41 10.7 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain ATG16 PF08614.11 CBZ31690.1 - 0.28 11.4 12.1 1.9 8.7 5.3 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) BRE1 PF08647.11 CBZ31690.1 - 2.1 8.5 7.7 0.072 13.2 1.6 1.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 CBZ31690.1 - 3.8 7.9 7.7 1.7 9.1 0.8 2.2 2 0 0 2 2 2 0 Fez1 ERM PF00769.19 CBZ31690.1 - 4.4 7.0 11.3 0.14 11.9 2.5 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family PrmC_N PF17827.1 CBZ31690.1 - 5.6 7.6 6.9 0.98 10.1 1.6 2.5 2 0 0 2 2 2 0 PrmC N-terminal domain ABC_tran_CTD PF16326.5 CBZ31691.1 - 0.44 10.8 0.0 0.44 10.8 0.0 6.7 4 3 3 7 7 7 0 ABC transporter C-terminal domain Thioredoxin PF00085.20 CBZ31692.1 - 3.1e-27 94.6 0.0 3.6e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CBZ31692.1 - 1.7e-05 25.2 0.1 6.3e-05 23.4 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBZ31692.1 - 9.3e-05 22.5 0.0 0.00013 22.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CBZ31692.1 - 0.0011 18.4 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 CBZ31692.1 - 0.0018 18.1 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 CBZ31692.1 - 0.0019 17.9 0.0 0.28 10.9 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_8 PF13905.6 CBZ31692.1 - 0.02 15.2 0.0 0.18 12.2 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like Defensin_propep PF00879.18 CBZ31692.1 - 1 9.7 2.7 1.7 9.0 2.7 1.2 1 0 0 1 1 1 0 Defensin propeptide 2OG-FeII_Oxy_2 PF13532.6 CBZ31693.1 - 5.3e-08 33.3 0.0 2.6e-07 31.0 0.0 1.8 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily TEX12 PF15219.6 CBZ31693.1 - 0.073 13.4 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Testis-expressed 12 DUF2188 PF09954.9 CBZ31693.1 - 0.094 12.9 0.7 0.29 11.3 0.7 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) DeoC PF01791.9 CBZ31694.1 - 5.6e-12 45.8 6.3 7.7e-12 45.3 6.3 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase PilX_N PF14341.6 CBZ31694.1 - 0.032 14.2 0.2 0.24 11.4 0.1 2.5 3 0 0 3 3 3 0 PilX N-terminal SNase PF00565.17 CBZ31695.1 - 8.8e-18 64.8 0.0 1.3e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ada_Zn_binding PF02805.16 CBZ31695.1 - 0.0045 17.0 0.5 0.014 15.4 0.2 2.0 2 0 0 2 2 2 1 Metal binding domain of Ada SYCE1 PF15233.6 CBZ31696.1 - 0.013 15.5 3.6 0.013 15.5 3.6 4.4 2 2 3 5 5 5 0 Synaptonemal complex central element protein 1 MAD PF05557.13 CBZ31696.1 - 0.29 9.5 50.1 0.14 10.5 3.4 3.1 2 1 1 3 3 3 0 Mitotic checkpoint protein DUF3450 PF11932.8 CBZ31696.1 - 0.31 10.3 46.4 0.018 14.3 11.1 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) OsmC PF02566.19 CBZ31696.1 - 0.34 11.4 2.8 0.6 10.6 0.3 2.6 2 1 0 2 2 2 0 OsmC-like protein Surfac_D-trimer PF09006.11 CBZ31696.1 - 1.2 9.0 3.5 3.5 7.6 0.4 3.2 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation CALCOCO1 PF07888.11 CBZ31696.1 - 1.9 7.2 52.4 0.0093 14.9 24.3 3.2 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Sporozoite_P67 PF05642.11 CBZ31696.1 - 3.2 5.7 8.4 0.077 11.1 1.0 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen GAS PF13851.6 CBZ31696.1 - 5.9 6.2 58.7 0.11 11.9 8.1 5.3 2 2 2 5 5 5 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 CBZ31696.1 - 9.9 6.2 56.6 0.39 10.7 6.7 4.8 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TraC PF07820.12 CBZ31697.1 - 0.17 12.3 2.7 0.56 10.6 0.0 2.5 2 0 0 2 2 2 0 TraC-like protein PIG-X PF08320.12 CBZ31699.1 - 6.8e-06 26.1 0.0 5.6e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 PIG-X / PBN1 WD40 PF00400.32 CBZ31700.1 - 7.2e-06 26.7 2.1 0.0066 17.3 0.2 4.6 4 2 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ31700.1 - 0.0016 18.7 0.5 0.36 11.2 0.0 3.1 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4340 PF14238.6 CBZ31700.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4340) Ge1_WD40 PF16529.5 CBZ31700.1 - 0.11 11.5 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RTT107_BRCT_5 PF16770.5 CBZ31701.1 - 2.7e-05 24.0 0.0 5.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 CBZ31701.1 - 0.014 15.8 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain DUF4379 PF14311.6 CBZ31702.1 - 1.4e-26 92.6 17.6 4e-09 36.7 0.3 4.7 4 0 0 4 4 4 4 Probable Zinc-ribbon domain HypA PF01155.19 CBZ31702.1 - 0.00023 21.1 15.0 0.11 12.5 0.0 4.3 3 2 1 5 5 5 3 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NTF2 PF02136.20 CBZ31704.1 - 1.2e-16 61.3 0.0 1.4e-16 61.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Pkinase PF00069.25 CBZ31705.1 - 3.5e-60 203.6 0.0 3.4e-37 128.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31705.1 - 2.9e-32 112.0 0.0 2e-23 83.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ31705.1 - 1.5e-05 25.1 0.0 0.11 12.5 0.0 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ31705.1 - 0.00084 18.7 0.0 0.0033 16.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBZ31705.1 - 0.0086 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ31705.1 - 0.039 12.9 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 CBZ31705.1 - 0.13 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Thioredoxin PF00085.20 CBZ31706.1 - 5.3e-10 39.2 0.0 6.5e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CBZ31706.1 - 0.00028 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DUF4055 PF13264.6 CBZ31709.1 - 0.26 11.5 1.0 3.3 7.9 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4055) PCO_ADO PF07847.12 CBZ31710.1 - 1.5e-53 181.3 0.0 2e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO CDO_I PF05995.12 CBZ31710.1 - 0.0047 16.3 0.1 3.1 7.1 0.1 2.2 2 0 0 2 2 2 2 Cysteine dioxygenase type I FAD_binding_3 PF01494.19 CBZ31711.1 - 1.7e-09 37.4 0.6 1.9e-08 34.0 0.0 2.4 2 1 0 2 2 2 1 FAD binding domain SE PF08491.10 CBZ31711.1 - 0.019 14.0 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Hpt PF01627.23 CBZ31711.1 - 0.19 12.0 0.8 0.53 10.6 0.0 2.0 2 0 0 2 2 2 0 Hpt domain EnY2 PF10163.9 CBZ31712.1 - 3e-06 27.5 0.0 4.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Transcription factor e(y)2 Phage_head_chap PF11113.8 CBZ31712.1 - 0.021 14.9 0.1 0.78 9.9 0.1 2.2 2 0 0 2 2 2 0 Head assembly gene product DUF5069 PF16798.5 CBZ31712.1 - 0.11 12.7 0.3 0.19 11.9 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5069) FA_hydroxylase PF04116.13 CBZ31713.1 - 0.16 12.3 1.2 0.51 10.7 0.1 2.1 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily Terminase_2 PF03592.16 CBZ31713.1 - 0.17 12.4 1.1 0.28 11.7 1.1 1.4 1 1 0 1 1 1 0 Terminase small subunit DFF-C PF09033.10 CBZ31713.1 - 0.91 9.4 4.6 0.8 9.6 3.3 1.5 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain TAF4 PF05236.14 CBZ31713.1 - 2.1 8.0 6.2 3.3 7.4 6.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family BT1 PF03092.16 CBZ31714.1 - 1.4e-189 630.7 9.7 1.6e-189 630.5 9.7 1.0 1 0 0 1 1 1 1 BT1 family Coprogen_oxidas PF01218.18 CBZ31715.1 - 6.3e-130 432.2 0.0 7.1e-130 432.0 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Flavodoxin_5 PF12724.7 CBZ31716.1 - 5.7e-46 156.3 0.1 7e-46 156.0 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_3 PF12641.7 CBZ31716.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin domain CLN3 PF02487.17 CBZ31719.1 - 1.2e-46 159.6 20.6 2.3e-46 158.7 19.2 2.0 2 1 0 2 2 2 1 CLN3 protein ThiF PF00899.21 CBZ31720.1 - 4.5e-40 137.6 0.0 7.7e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 CBZ31720.1 - 1.7e-26 93.5 0.0 2.5e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 CBZ31720.1 - 5.7e-05 23.2 0.1 0.0047 17.0 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CBZ31720.1 - 0.063 12.6 0.0 8.5 5.7 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 CBZ31720.1 - 0.33 10.8 2.8 12 5.8 0.2 2.8 2 1 1 3 3 3 0 KR domain Isy1 PF06246.12 CBZ31721.1 - 1e-23 84.2 13.7 1.1e-22 80.8 13.7 2.3 1 1 0 1 1 1 1 Isy1-like splicing family CytoC_RC PF02276.18 CBZ31721.1 - 0.19 11.1 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit DOT1 PF08123.13 CBZ31722.1 - 4e-20 72.2 0.0 6.7e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 CBZ31722.1 - 1.4e-05 25.7 0.0 2.9e-05 24.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ31722.1 - 6.1e-05 22.9 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ31722.1 - 0.00027 21.5 0.0 0.0006 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CBZ31722.1 - 0.00076 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBZ31722.1 - 0.0078 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CBZ31722.1 - 0.023 15.4 0.0 0.038 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF4268 PF14088.6 CBZ31722.1 - 0.026 14.4 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) AdoMet_MTase PF07757.13 CBZ31722.1 - 0.074 13.4 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 CBZ31722.1 - 0.076 12.9 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CBZ31722.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain M20_dimer PF07687.14 CBZ31723.1 - 1.7e-05 24.7 0.6 2.8e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Peptidase dimerisation domain RsgA_GTPase PF03193.16 CBZ31724.1 - 0.1 12.5 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase Adaptin_N PF01602.20 CBZ31725.1 - 2.9e-86 290.1 8.5 3.7e-86 289.8 8.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBZ31725.1 - 4.7e-05 23.5 1.8 0.0052 16.8 0.0 2.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF5315 PF17242.2 CBZ31725.1 - 0.0025 17.6 0.0 0.0071 16.1 0.0 1.7 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) HEAT PF02985.22 CBZ31725.1 - 0.049 13.9 0.1 0.74 10.2 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat EamA PF00892.20 CBZ31726.1 - 7.5e-15 55.3 28.3 3.3e-08 33.8 1.2 3.2 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 CBZ31726.1 - 4.7e-05 22.8 0.1 4.7e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 CBZ31726.1 - 9.4e-05 22.1 5.3 9.4e-05 22.1 5.3 1.5 2 0 0 2 2 2 1 Solute carrier family 35 AIMP2_LysRS_bd PF16780.5 CBZ31727.1 - 0.25 11.1 0.6 2.5 7.9 0.0 2.7 2 0 0 2 2 2 0 AIMP2 lysyl-tRNA synthetase binding domain Rav1p_C PF12234.8 CBZ31728.1 - 4.8e-37 127.7 0.8 3e-26 92.0 3.5 3.1 2 1 0 2 2 2 2 RAVE protein 1 C terminal zf-C3HC4 PF00097.25 CBZ31729.1 - 1.4e-06 28.0 10.3 3.3e-06 26.9 10.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ31729.1 - 2.1e-06 27.6 9.8 6.2e-06 26.1 9.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBZ31729.1 - 1.6e-05 24.6 9.6 4.8e-05 23.1 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ31729.1 - 1.7e-05 24.6 11.1 4.9e-05 23.1 11.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ31729.1 - 3e-05 24.3 10.9 3e-05 24.3 10.9 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CBZ31729.1 - 8.4e-05 22.6 9.1 0.0002 21.4 9.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-TRAF PF02176.18 CBZ31729.1 - 0.00016 22.3 0.4 0.0005 20.7 0.4 1.9 1 0 0 1 1 1 1 TRAF-type zinc finger Prok-RING_4 PF14447.6 CBZ31729.1 - 0.00084 19.1 8.9 0.00084 19.1 8.9 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBZ31729.1 - 0.0022 17.9 10.5 0.0061 16.5 10.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CBZ31729.1 - 0.0027 17.9 8.1 0.011 15.9 8.1 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain Sina PF03145.16 CBZ31729.1 - 0.014 15.4 0.4 0.024 14.6 0.4 1.3 1 0 0 1 1 1 0 Seven in absentia protein family U-box PF04564.15 CBZ31729.1 - 0.025 14.8 0.0 0.094 12.9 0.0 2.1 2 0 0 2 2 2 0 U-box domain zf-TRAF_2 PF15965.5 CBZ31729.1 - 0.035 14.6 0.5 0.035 14.6 0.5 2.6 2 1 0 2 2 1 0 TRAF-like zinc-finger zf-Nse PF11789.8 CBZ31729.1 - 0.12 12.2 3.6 0.49 10.3 3.6 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DEAD PF00270.29 CBZ31732.1 - 2.2e-45 154.6 0.0 3.6e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ31732.1 - 2.9e-24 85.6 0.0 1.7e-23 83.0 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ31732.1 - 0.0056 16.7 0.0 0.018 15.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 CBZ31732.1 - 0.047 13.8 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain CMS1 PF14617.6 CBZ31732.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit RIBIOP_C PF04950.12 CBZ31733.1 - 2.8e-93 312.5 0.0 5.1e-93 311.7 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CBZ31733.1 - 5.1e-16 58.5 0.0 1.5e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MATalpha_HMGbox PF04769.12 CBZ31733.1 - 0.034 13.4 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Acyl-CoA_dh_N PF02771.16 CBZ31734.1 - 3.1e-10 40.7 0.0 7.3e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBZ31734.1 - 0.00018 21.7 0.1 0.00058 20.0 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBZ31734.1 - 0.58 10.4 5.1 1.6 9.0 1.9 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain MaoC_dehydratas PF01575.19 CBZ31736.1 - 1.2e-22 79.7 0.0 1.6e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CBZ31736.1 - 1.4e-12 47.9 0.0 2.9e-12 46.8 0.0 1.6 1 1 1 2 2 2 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 CBZ31736.1 - 0.00071 19.9 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 CBZ31736.1 - 0.1 13.1 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily MaoC_dehydratas PF01575.19 CBZ31737.1 - 2e-22 79.1 0.0 2.9e-22 78.5 0.0 1.3 1 1 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CBZ31737.1 - 7.4e-10 39.1 0.0 1.1e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase 4HBT PF03061.22 CBZ31737.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 2 0 0 2 2 2 0 Thioesterase superfamily RL10P_insert PF17777.1 CBZ31737.1 - 0.14 12.1 0.0 1.2 9.2 0.0 2.0 2 0 0 2 2 2 0 Insertion domain in 60S ribosomal protein L10P SIN1_PH PF16979.5 CBZ31739.1 - 8.4e-09 35.7 0.3 1.5e-08 34.8 0.3 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Ring_hydroxyl_A PF00848.19 CBZ31739.1 - 0.042 13.8 0.1 0.56 10.1 0.0 2.3 2 0 0 2 2 2 0 Ring hydroxylating alpha subunit (catalytic domain) Cytochrom_C1 PF02167.15 CBZ31740.1 - 1e-76 257.5 0.0 1.2e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Tad PF13400.6 CBZ31742.1 - 0.17 12.2 0.3 0.41 11.0 0.3 1.6 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Met_synt_B12 PF02965.17 CBZ31743.1 - 1.4e-107 359.3 0.1 2.6e-107 358.4 0.0 1.5 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 CBZ31743.1 - 2.7e-75 253.6 0.0 7.2e-75 252.2 0.0 1.8 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 CBZ31743.1 - 3.9e-48 164.3 0.3 5e-46 157.3 0.2 2.5 2 0 0 2 2 2 2 Pterin binding enzyme B12-binding_2 PF02607.17 CBZ31743.1 - 1.7e-24 86.0 0.5 5.1e-24 84.5 0.1 2.2 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 CBZ31743.1 - 6e-21 74.7 0.4 6.2e-20 71.4 0.4 2.7 3 0 0 3 3 3 1 B12 binding domain GAIN PF16489.5 CBZ31743.1 - 0.13 11.7 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain M16C_assoc PF08367.11 CBZ31744.1 - 8.7e-28 97.1 0.0 1.6e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CBZ31744.1 - 1.4e-22 80.6 0.0 5.4e-15 55.9 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CBZ31744.1 - 5.7e-16 58.8 1.5 3.6e-12 46.5 0.0 3.0 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) EF-hand_1 PF00036.32 CBZ31745.1 - 2.2e-23 80.0 6.1 6e-07 28.6 0.1 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CBZ31745.1 - 3.2e-23 82.0 0.0 3.1e-06 27.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBZ31745.1 - 4.1e-21 73.1 1.2 0.00022 20.9 0.1 5.6 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 CBZ31745.1 - 4.5e-21 74.4 1.7 2.2e-05 24.2 0.2 4.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CBZ31745.1 - 6e-16 57.1 3.8 5.1e-06 25.7 0.0 4.6 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 CBZ31745.1 - 0.0007 19.5 0.0 2.1 8.4 0.0 3.2 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBZ31745.1 - 0.0054 17.0 0.0 0.85 10.0 0.0 2.9 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBZ31745.1 - 0.018 15.9 0.3 2.9 8.8 0.0 3.5 3 1 1 4 4 4 0 EF-hand domain TFIID-18kDa PF02269.16 CBZ31745.1 - 0.022 14.7 0.0 3.5 7.7 0.0 3.5 4 0 0 4 4 4 0 Transcription initiation factor IID, 18kD subunit EF-hand_9 PF14658.6 CBZ31745.1 - 0.027 14.8 1.3 6.4 7.2 0.0 3.7 5 0 0 5 5 5 0 EF-hand domain Sec7 PF01369.20 CBZ31746.1 - 1.4e-36 125.9 0.0 2.5e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CBZ31746.1 - 0.071 13.0 0.0 1 9.2 0.0 2.7 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal tRNA_Me_trans PF03054.16 CBZ31747.1 - 1.3e-39 136.0 0.0 4.7e-26 91.4 0.0 4.5 4 0 0 4 4 4 4 tRNA methyl transferase NAD_synthase PF02540.17 CBZ31747.1 - 0.025 13.7 0.1 0.051 12.7 0.1 1.4 1 0 0 1 1 1 0 NAD synthase Asn_synthase PF00733.21 CBZ31747.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase DUF1751 PF08551.10 CBZ31748.1 - 0.00011 22.7 1.0 0.00028 21.4 0.5 1.9 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CBZ31748.1 - 0.13 12.2 1.4 0.18 11.8 0.2 1.8 2 0 0 2 2 2 0 Rhomboid family DUF747 PF05346.11 CBZ31749.1 - 8.9e-71 239.0 1.8 1.2e-70 238.5 1.8 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Pkinase PF00069.25 CBZ31750.1 - 7.2e-50 169.8 0.0 1.1e-49 169.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31750.1 - 6e-32 110.9 0.0 1e-31 110.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ31750.1 - 1.5e-06 27.8 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ31750.1 - 0.051 13.5 0.0 0.051 13.5 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 CBZ31750.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 CBZ31750.1 - 0.17 10.6 1.5 0.21 10.3 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Pkinase PF00069.25 CBZ31751.1 - 3e-48 164.5 0.0 4e-28 98.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31751.1 - 9.3e-34 116.9 0.0 5.8e-20 71.7 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ31751.1 - 0.012 14.9 0.1 0.67 9.2 0.1 2.3 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CBZ31751.1 - 0.023 14.0 0.2 0.18 11.1 0.2 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBZ31751.1 - 0.056 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase PTPA PF03095.15 CBZ31753.1 - 1.1e-96 323.8 0.0 1.4e-96 323.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein PLDc_2 PF13091.6 CBZ31754.1 - 7.6e-10 38.8 0.0 0.00017 21.5 0.0 3.7 2 2 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CBZ31754.1 - 6.4e-07 29.3 0.2 1.6e-05 24.8 0.1 2.8 3 0 0 3 3 3 1 Phospholipase D Active site motif HNF_C PF09354.10 CBZ31754.1 - 0.02 15.9 0.0 0.057 14.5 0.0 1.8 1 0 0 1 1 1 0 HNF3 C-terminal domain CIAPIN1 PF05093.13 CBZ31757.1 - 1e-14 54.8 16.8 6.2e-11 42.7 4.4 2.2 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pkinase PF00069.25 CBZ31759.1 - 7.5e-36 123.8 0.0 8.9e-14 51.5 0.0 3.8 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31759.1 - 3.8e-16 59.1 0.0 8.7e-11 41.6 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ31759.1 - 0.15 11.3 0.0 0.5 9.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Homoserine_dh PF00742.19 CBZ31760.1 - 7.6e-54 182.2 0.0 1.1e-53 181.7 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CBZ31760.1 - 1.8e-10 41.5 0.1 3.7e-10 40.5 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Peptidase_M20 PF01546.28 CBZ31761.1 - 2.5e-34 118.8 0.0 3.7e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ31761.1 - 4.9e-18 65.0 0.0 8.3e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain HECT PF00632.25 CBZ31762.1 - 1.2e-88 297.6 0.0 1.7e-88 297.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_2 PF03107.16 CBZ31762.1 - 1.3e-06 28.6 7.7 2.7e-06 27.6 7.7 1.6 1 0 0 1 1 1 1 C1 domain ZZ PF00569.17 CBZ31762.1 - 0.14 12.0 8.4 0.32 10.9 8.4 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type UPF0172 PF03665.13 CBZ31763.1 - 3e-50 170.9 0.0 3.6e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) LRR_4 PF12799.7 CBZ31764.1 - 0.00012 22.4 1.7 0.00055 20.3 1.3 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ31764.1 - 0.054 13.3 2.9 0.4 10.5 3.5 1.7 1 1 0 1 1 1 0 Leucine rich repeat Flagellar_rod PF05149.12 CBZ31765.1 - 4.9e-09 36.1 17.7 4.9e-09 36.1 17.7 2.5 3 0 0 3 3 3 1 Paraflagellar rod protein zf-C2H2_8 PF15909.5 CBZ31765.1 - 0.13 12.6 0.9 3.3 8.1 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc ribbon DUF5448 PF17526.2 CBZ31765.1 - 0.2 11.9 1.1 1.4 9.1 0.2 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5448) Sec20 PF03908.13 CBZ31765.1 - 1.1 9.3 3.0 16 5.5 0.1 2.9 3 0 0 3 3 3 0 Sec20 ABA_GPCR PF12430.8 CBZ31767.1 - 2.1e-32 112.3 0.7 2.1e-32 112.3 0.7 2.0 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CBZ31767.1 - 7.6e-08 32.3 0.0 2.8e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF3382 PF11862.8 CBZ31767.1 - 0.0036 17.5 3.2 0.037 14.3 0.2 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3382) NUDIX PF00293.28 CBZ31768.1 - 9.3e-10 38.7 0.0 1.9e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DHC_N2 PF08393.13 CBZ31770.1 - 1.4e-40 139.7 0.0 3.3e-40 138.4 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 CBZ31770.1 - 1.5e-06 27.9 0.0 1.7e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_8 PF12780.7 CBZ31770.1 - 0.0018 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_6 PF12774.7 CBZ31770.1 - 0.0071 15.4 0.0 0.018 14.0 0.0 1.7 1 1 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 CBZ31770.1 - 0.019 15.4 0.0 0.072 13.5 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APG17 PF04108.12 CBZ31770.1 - 3.3 6.7 8.1 9 5.3 0.1 2.7 2 0 0 2 2 2 0 Autophagy protein Apg17 Exonuc_VII_L PF02601.15 CBZ31770.1 - 5.7 6.4 7.3 3 7.3 3.2 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF4611 PF15387.6 CBZ31771.1 - 2.9 8.2 8.3 7.5 6.9 8.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 CBZ31771.1 - 4.3 5.3 7.9 6.3 4.8 7.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 CBZ31771.1 - 6 7.3 12.3 16 6.0 12.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_L7Ae PF01248.26 CBZ31772.1 - 6e-20 70.8 0.2 1.2e-19 69.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CBZ31772.1 - 0.00029 20.9 0.1 0.00045 20.3 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Sec20 PF03908.13 CBZ31773.1 - 0.00022 21.1 0.9 0.00062 19.6 0.7 1.9 1 1 1 2 2 2 1 Sec20 Neur_chan_memb PF02932.16 CBZ31773.1 - 0.028 14.5 0.4 0.041 13.9 0.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cytochrom_B562 PF07361.11 CBZ31773.1 - 0.03 15.0 1.1 0.03 15.0 1.1 2.3 2 0 0 2 2 2 0 Cytochrome b562 V-SNARE_C PF12352.8 CBZ31773.1 - 0.05 13.9 1.4 0.12 12.7 1.4 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus CCDC-167 PF15188.6 CBZ31773.1 - 0.092 13.1 3.7 0.84 10.0 0.3 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Snapin_Pallidin PF14712.6 CBZ31773.1 - 0.22 12.0 5.9 0.33 11.4 2.8 2.4 2 1 0 2 2 2 0 Snapin/Pallidin TSNAXIP1_N PF15739.5 CBZ31773.1 - 5.1 7.5 9.3 16 5.9 0.3 2.4 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Mito_carr PF00153.27 CBZ31774.1 - 1.6e-31 108.1 4.5 1.2e-12 47.6 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Arm_vescicular PF18770.1 CBZ31774.1 - 0.045 13.7 0.1 0.12 12.4 0.1 1.7 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor Ras PF00071.22 CBZ31777.1 - 8.8e-55 184.7 0.0 1e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ31777.1 - 3.9e-29 101.3 0.0 5.4e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ31777.1 - 1e-10 41.4 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBZ31777.1 - 0.00044 20.3 0.0 0.00079 19.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ31777.1 - 0.00065 19.3 0.0 0.016 14.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBZ31777.1 - 0.0095 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region CLP1_P PF16575.5 CBZ31779.1 - 3.1e-27 95.6 0.0 8.2e-27 94.2 0.0 1.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 CBZ31779.1 - 0.029 14.7 1.6 0.072 13.5 0.1 2.5 2 0 0 2 2 2 0 AAA ATPase domain DUF4778 PF16008.5 CBZ31779.1 - 1.2 9.1 3.6 2.8 7.9 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Sel1 PF08238.12 CBZ31780.1 - 3.6e-21 75.1 35.4 4.3e-08 33.6 0.1 8.6 8 0 0 8 8 8 6 Sel1 repeat Sel1 PF08238.12 CBZ31781.1 - 3.6e-21 75.1 35.4 4.3e-08 33.6 0.1 8.6 8 0 0 8 8 8 6 Sel1 repeat ETF_QO PF05187.13 CBZ31782.1 - 1.1e-43 147.6 0.2 2e-43 146.7 0.2 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CBZ31782.1 - 5.2e-08 32.9 3.2 0.00038 20.1 1.4 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CBZ31782.1 - 5.7e-08 32.3 2.4 0.0018 17.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CBZ31782.1 - 1.6e-06 28.3 0.2 6.1e-06 26.4 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CBZ31782.1 - 1.4e-05 24.4 0.0 0.016 14.4 0.2 2.2 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.27 CBZ31782.1 - 6.7e-05 23.4 0.1 0.3 11.7 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CBZ31782.1 - 6.9e-05 22.9 0.2 0.00014 21.9 0.2 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CBZ31782.1 - 0.00026 20.3 0.0 0.00042 19.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ31782.1 - 0.0049 15.6 0.3 0.0074 15.0 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 CBZ31782.1 - 0.011 14.7 0.5 0.089 11.6 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_3 PF01494.19 CBZ31782.1 - 0.026 13.8 1.0 0.036 13.3 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 CBZ31782.1 - 0.03 13.6 0.1 0.042 13.1 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ31782.1 - 0.046 12.8 0.1 0.071 12.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 CBZ31782.1 - 0.11 11.9 0.3 0.15 11.4 0.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NPL PF17800.1 CBZ31783.1 - 6.5e-11 42.7 0.0 1.1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoplasmin-like domain CcdB PF01845.17 CBZ31785.1 - 0.043 14.0 0.5 0.19 12.0 0.5 2.1 1 0 0 1 1 1 0 CcdB protein Pox_A_type_inc PF04508.12 CBZ31785.1 - 0.074 12.9 6.8 2.4 8.2 0.0 4.3 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat ZapB PF06005.12 CBZ31785.1 - 0.26 11.7 0.1 0.26 11.7 0.1 6.0 5 1 1 6 6 6 0 Cell division protein ZapB Golgin_A5 PF09787.9 CBZ31785.1 - 0.34 10.3 24.6 0.42 10.0 2.3 3.6 3 0 0 3 3 3 0 Golgin subfamily A member 5 BBP1_C PF15272.6 CBZ31785.1 - 1.8 8.3 13.6 17 5.2 5.9 4.0 2 2 1 3 3 3 0 Spindle pole body component BBP1, C-terminal PRKG1_interact PF15898.5 CBZ31785.1 - 6 7.8 29.0 2 9.4 2.0 5.3 5 1 0 5 5 5 0 cGMP-dependent protein kinase interacting domain PKcGMP_CC PF16808.5 CBZ31785.1 - 7.4 6.5 15.7 1.6 8.6 1.1 4.4 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase E1-E2_ATPase PF00122.20 CBZ31786.1 - 1.7e-33 115.7 0.1 1.1e-32 113.0 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBZ31786.1 - 2e-30 105.8 0.2 4.7e-30 104.7 0.2 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 CBZ31786.1 - 1.1e-13 50.7 0.0 2.1e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CBZ31786.1 - 2.1e-13 51.1 0.2 1.3e-11 45.2 0.1 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ31786.1 - 5.5e-12 45.6 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBZ31786.1 - 4e-06 26.8 0.0 0.00034 20.4 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4179 PF13786.6 CBZ31786.1 - 0.011 16.2 0.0 0.045 14.2 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF1980 PF09323.10 CBZ31786.1 - 0.1 12.5 0.0 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) JAB PF01398.21 CBZ31787.1 - 0.011 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cation_ATPase_N PF00690.26 CBZ31788.1 - 6.9e-06 25.7 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus V-SNARE_C PF12352.8 CBZ31790.1 - 1.2e-08 35.0 5.1 2e-08 34.4 5.1 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Synaptobrevin PF00957.21 CBZ31790.1 - 0.066 13.0 2.2 0.22 11.4 2.2 1.8 1 1 0 1 1 1 0 Synaptobrevin IL2 PF00715.17 CBZ31790.1 - 0.22 11.5 0.7 1.9 8.4 0.0 2.0 1 1 1 2 2 2 0 Interleukin 2 Pkinase PF00069.25 CBZ31791.1 - 9e-40 136.7 0.0 2.3e-25 89.5 0.0 3.5 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31791.1 - 2.4e-22 79.5 0.0 7.4e-16 58.2 0.0 2.9 3 1 0 3 3 3 2 Protein tyrosine kinase PAP_assoc PF03828.19 CBZ31792.1 - 0.0034 17.6 0.0 0.015 15.5 0.0 2.1 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBZ31792.1 - 0.0097 16.2 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain EF-hand_1 PF00036.32 CBZ31793.1 - 5e-27 91.4 8.6 8.2e-09 34.4 0.7 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CBZ31793.1 - 1.2e-25 89.7 2.1 1.1e-12 48.2 0.9 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ31793.1 - 2.7e-23 79.9 3.7 1.1e-09 37.5 0.1 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CBZ31793.1 - 4e-18 65.0 9.2 2.7e-12 46.3 0.7 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CBZ31793.1 - 5.9e-13 47.7 10.0 1.9e-05 23.9 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CBZ31793.1 - 1.4e-10 41.3 0.2 4.7e-05 23.6 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 CBZ31793.1 - 1.8e-06 27.8 0.9 0.01 15.7 0.0 2.7 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SUB1_ProdP9 PF18213.1 CBZ31793.1 - 0.0012 18.6 0.1 0.002 17.9 0.1 1.4 1 0 0 1 1 1 1 SUB1 protease Prodomain ProdP9 EF-hand_14 PF17959.1 CBZ31793.1 - 0.0054 17.1 0.4 2.5 8.5 0.1 2.7 2 2 0 2 2 2 2 EF-hand domain HEAT PF02985.22 CBZ31795.1 - 6.6e-11 41.5 15.8 0.0012 18.9 0.2 9.8 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 CBZ31795.1 - 2.9e-09 37.2 19.6 0.00028 21.2 0.1 7.1 6 1 1 7 7 7 4 HEAT repeats HEAT_EZ PF13513.6 CBZ31795.1 - 1.2e-05 25.7 23.6 0.00018 21.9 1.2 9.8 8 1 2 10 10 10 3 HEAT-like repeat Cnd1 PF12717.7 CBZ31795.1 - 0.0003 20.9 0.0 0.082 13.0 0.0 4.5 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 CBZ31795.1 - 0.00059 19.7 0.1 0.0079 16.1 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 CBZ31795.1 - 0.0011 18.6 0.4 6.2 6.3 0.0 3.7 3 1 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 CBZ31795.1 - 0.0091 16.2 0.0 14 5.9 0.0 4.2 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 CBZ31795.1 - 0.012 15.5 1.4 0.71 9.8 0.1 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF3437) GLE1 PF07817.13 CBZ31795.1 - 0.032 13.4 0.7 0.069 12.4 0.1 1.8 2 0 0 2 2 2 0 GLE1-like protein MMS19_C PF12460.8 CBZ31795.1 - 0.036 13.2 1.8 0.7 8.9 0.1 3.1 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal YdaT_toxin PF06254.11 CBZ31795.1 - 0.068 13.7 0.7 3.5 8.3 0.0 3.2 3 0 0 3 3 3 0 Putative bacterial toxin ydaT HEAT_PBS PF03130.16 CBZ31795.1 - 1.5 9.7 9.2 21 6.2 0.1 5.4 4 1 1 5 5 5 0 PBS lyase HEAT-like repeat Arm PF00514.23 CBZ31795.1 - 1.5 9.0 5.3 14 5.9 0.1 5.1 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat MCD PF05292.11 CBZ31796.1 - 1.7e-61 208.1 0.1 3.8e-58 197.1 0.0 3.8 2 1 0 2 2 2 1 Malonyl-CoA decarboxylase C-terminal domain PPI_Ypi1 PF07491.11 CBZ31798.1 - 1.1e-17 63.5 0.9 1.1e-17 63.5 0.9 1.7 2 0 0 2 2 2 1 Protein phosphatase inhibitor IMUP PF15761.5 CBZ31798.1 - 4 8.2 15.8 8.3 7.1 15.8 1.7 1 1 0 1 1 1 0 Immortalisation up-regulated protein His_Phos_1 PF00300.22 CBZ31801.1 - 5e-30 104.6 0.4 1.4e-22 80.4 0.0 2.7 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 CBZ31801.1 - 9.6e-18 64.3 0.2 3.2e-10 39.7 0.0 3.3 3 0 0 3 3 3 3 6-phosphofructo-2-kinase AAA_33 PF13671.6 CBZ31801.1 - 0.11 12.6 1.7 0.62 10.2 0.0 3.1 4 0 0 4 4 4 0 AAA domain DnaJ PF00226.31 CBZ31802.1 - 8e-06 25.9 0.1 4.4e-05 23.5 0.0 2.1 2 1 0 2 2 2 1 DnaJ domain DnaJ PF00226.31 CBZ31803.1 - 3.2e-07 30.4 0.0 8.3e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CBZ31803.1 - 2.7e-05 24.2 0.0 7.3e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Pam16 FAD_binding_2 PF00890.24 CBZ31805.1 - 5e-60 203.7 2.6 7.2e-60 203.2 2.6 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 CBZ31805.1 - 1e-20 73.6 0.1 1.4e-19 70.0 0.0 2.6 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.22 CBZ31806.1 - 0.00062 19.5 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGM_PMM_I PF02878.16 CBZ31807.1 - 1.2e-12 47.7 0.0 3.9e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CBZ31807.1 - 6.8e-11 42.2 0.0 1.7e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CBZ31807.1 - 0.012 15.8 0.1 0.023 14.9 0.1 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CBZ31807.1 - 0.02 15.5 0.6 0.38 11.4 0.3 2.8 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Cyt-b5 PF00173.28 CBZ31808.1 - 0.05 13.7 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Bile_Hydr_Trans PF04775.14 CBZ31811.1 - 0.16 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region UQ_con PF00179.26 CBZ31814.1 - 2.4e-39 134.2 0.0 3.6e-39 133.6 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBZ31814.1 - 0.051 13.3 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B CAMSAP_CC1 PF17095.5 CBZ31815.1 - 0.75 9.7 6.0 2.2 8.2 6.0 1.8 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Pkinase PF00069.25 CBZ31817.1 - 8.6e-77 258.0 0.0 1e-76 257.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31817.1 - 2.2e-39 135.3 0.0 2.7e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ31817.1 - 1.3e-10 41.1 0.0 2.6e-08 33.5 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 CBZ31817.1 - 0.0007 18.6 0.2 0.00097 18.2 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBZ31817.1 - 0.00095 18.6 0.2 0.0016 17.8 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ31817.1 - 0.0044 17.0 0.2 0.19 11.6 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 CBZ31818.1 - 2.4e-51 174.6 0.0 4.1e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31818.1 - 5.1e-35 121.0 0.1 1.5e-33 116.2 0.1 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase PX PF00787.24 CBZ31818.1 - 0.0042 17.0 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 CBZ31818.1 - 0.076 12.3 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Kinase-like PKD_channel PF08016.12 CBZ31820.1 - 0.01 14.6 11.5 0.016 13.9 11.5 1.2 1 0 0 1 1 1 0 Polycystin cation channel IML1 PF12257.8 CBZ31821.1 - 2.4e-37 128.6 0.0 3.4e-28 98.6 0.1 3.1 2 1 0 2 2 2 2 Vacuolar membrane-associated protein Iml1 Radial_spoke PF04712.12 CBZ31822.1 - 2.6e-05 23.4 8.6 0.0012 17.9 7.5 2.8 2 1 0 2 2 2 1 Radial spokehead-like protein CENP-B_dimeris PF09026.10 CBZ31822.1 - 0.00027 21.2 5.4 0.00046 20.5 5.4 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PBP1_TM PF14812.6 CBZ31822.1 - 0.54 10.7 3.4 0.93 9.9 3.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4632 PF15451.6 CBZ31822.1 - 0.87 9.7 3.2 1.7 8.8 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Ribosomal_60s PF00428.19 CBZ31822.1 - 1.1 9.9 14.0 1.9 9.1 14.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein CDC45 PF02724.14 CBZ31822.1 - 1.5 7.0 3.8 1.9 6.7 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CBZ31822.1 - 1.7 6.7 8.7 2.1 6.3 8.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 CBZ31822.1 - 2.4 7.4 9.4 3.8 6.8 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein Astro_capsid_p PF12226.8 CBZ31822.1 - 3.1 6.9 5.3 4.2 6.4 5.3 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nop14 PF04147.12 CBZ31822.1 - 3.8 5.6 7.1 4.8 5.3 7.1 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3437 PF11919.8 CBZ31823.1 - 3.5e-19 68.5 0.0 1.6e-18 66.4 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_mid PF16507.5 CBZ31823.1 - 0.27 9.8 0.0 5.8 5.4 0.0 2.2 2 0 0 2 2 2 0 Proteasome-substrate-size regulator, mid region Sel1 PF08238.12 CBZ31826.1 - 5.4e-06 26.9 4.2 0.3 11.8 3.7 3.4 2 1 0 2 2 2 2 Sel1 repeat ATPgrasp_N PF18130.1 CBZ31826.1 - 0.096 13.2 0.1 0.26 11.8 0.1 1.7 1 0 0 1 1 1 0 ATP-grasp N-terminal domain E1-E2_ATPase PF00122.20 CBZ31827.1 - 2.4e-22 79.4 0.1 7.2e-22 77.8 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CBZ31827.1 - 3.4e-12 47.1 1.9 6e-05 23.4 1.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ31827.1 - 0.0016 18.5 0.0 0.0039 17.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBZ31827.1 - 0.012 15.4 0.3 0.044 13.5 0.1 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Dpy-30 PF05186.13 CBZ31828.1 - 1.1e-11 44.2 0.0 1.5e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Dpy-30 motif zf-C2H2 PF00096.26 CBZ31830.1 - 3.5e-07 30.3 7.8 0.0009 19.6 0.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CBZ31830.1 - 5.2e-07 30.0 7.8 0.006 17.3 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CBZ31830.1 - 0.00013 22.7 0.2 0.41 11.3 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats DUF629 PF04780.12 CBZ31830.1 - 0.00052 18.7 1.1 0.44 9.0 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.7 CBZ31830.1 - 0.0031 17.8 3.3 0.31 11.4 0.4 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CBZ31830.1 - 0.0052 16.8 6.1 0.54 10.3 0.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CBZ31830.1 - 0.011 15.4 1.6 2.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 CBZ31830.1 - 0.011 16.0 1.8 1.6 9.1 0.4 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-trcl PF13451.6 CBZ31830.1 - 0.028 14.3 1.5 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain PHD_Oberon PF07227.11 CBZ31830.1 - 0.037 13.9 1.6 0.41 10.5 0.4 2.2 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein TFIIS_C PF01096.18 CBZ31830.1 - 0.04 13.8 3.8 1.2 9.0 0.5 2.7 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf_UBZ PF18439.1 CBZ31830.1 - 0.068 12.8 1.0 4.5 6.9 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 CBZ31830.1 - 0.073 13.5 3.3 7.8 7.1 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger double domain ARS2 PF04959.13 CBZ31830.1 - 0.075 13.4 0.0 2.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Arsenite-resistance protein 2 zf-met PF12874.7 CBZ31830.1 - 0.075 13.4 4.3 0.1 13.0 1.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CpXC PF14353.6 CBZ31830.1 - 0.076 13.1 0.4 12 6.0 0.1 2.3 2 0 0 2 2 2 0 CpXC protein OrsD PF12013.8 CBZ31830.1 - 0.11 13.0 1.5 0.76 10.2 0.1 2.3 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Zn-ribbon_8 PF09723.10 CBZ31830.1 - 0.11 12.7 1.3 2.1 8.5 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain HNH PF01844.23 CBZ31830.1 - 0.12 12.6 0.7 6.2 7.1 0.1 2.4 2 0 0 2 2 2 0 HNH endonuclease Actin_micro PF17003.5 CBZ31830.1 - 0.19 10.8 0.2 3 6.9 0.0 2.0 2 0 0 2 2 2 0 Putative actin-like family zf-C2H2_jaz PF12171.8 CBZ31830.1 - 0.33 11.3 4.4 0.81 10.0 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met2 PF12907.7 CBZ31830.1 - 0.52 10.5 6.7 0.064 13.4 1.3 2.2 2 0 0 2 2 2 0 Zinc-binding zf-LYAR PF08790.11 CBZ31830.1 - 0.61 10.0 3.6 16 5.5 0.4 2.7 3 0 0 3 3 2 0 LYAR-type C2HC zinc finger DUF1601 PF07671.11 CBZ31831.1 - 0.034 14.0 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) MAD PF05557.13 CBZ31831.1 - 0.17 10.3 26.6 0.25 9.6 26.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein ERM PF00769.19 CBZ31831.1 - 0.4 10.5 30.3 0.85 9.4 30.3 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Filament PF00038.21 CBZ31831.1 - 1.7 8.2 25.0 3.4 7.2 25.0 1.5 1 0 0 1 1 1 0 Intermediate filament protein YjbH PF06082.11 CBZ31831.1 - 2 7.1 6.0 2.7 6.7 6.0 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF489 PF04356.12 CBZ31831.1 - 2.7 7.9 8.4 1 9.4 1.1 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF489) NPL PF17800.1 CBZ31832.1 - 4.6e-12 46.4 0.0 4.6e-12 46.4 0.0 2.6 2 1 0 2 2 2 1 Nucleoplasmin-like domain FeS_assembly_P PF01883.19 CBZ31833.1 - 3.6e-10 39.9 0.0 9.6e-10 38.5 0.0 1.7 2 1 0 2 2 2 1 Iron-sulfur cluster assembly protein Glyco_hydro_1 PF00232.18 CBZ31833.1 - 0.15 10.4 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 PIF1 PF05970.14 CBZ31834.1 - 1.3e-44 152.9 0.0 7e-36 124.2 0.0 2.8 3 0 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 CBZ31834.1 - 2.6e-16 59.9 0.0 4.8e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CBZ31834.1 - 9.7e-11 40.3 1.4 5.6e-06 24.6 0.0 2.1 2 0 0 2 2 2 2 Helicase AAA_19 PF13245.6 CBZ31834.1 - 5.9e-09 36.4 0.0 2e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CBZ31834.1 - 1.6e-05 24.8 0.1 0.00044 20.1 0.0 3.1 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CBZ31834.1 - 5.9e-05 23.4 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBZ31834.1 - 0.00023 21.2 0.0 0.00064 19.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) T2SSE PF00437.20 CBZ31834.1 - 0.00032 19.9 0.0 0.0007 18.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 CBZ31834.1 - 0.0011 19.4 0.1 0.0029 18.0 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.6 CBZ31834.1 - 0.0015 18.4 0.0 0.086 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBZ31834.1 - 0.0052 16.3 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 CBZ31834.1 - 0.014 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain UvrD_C_2 PF13538.6 CBZ31834.1 - 0.044 13.6 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain SH3_13 PF18335.1 CBZ31834.1 - 0.047 13.5 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain NTPase_1 PF03266.15 CBZ31834.1 - 0.048 13.6 0.2 0.71 9.8 0.3 2.3 2 0 0 2 2 2 0 NTPase AFG1_ATPase PF03969.16 CBZ31834.1 - 0.064 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase AAA_14 PF13173.6 CBZ31834.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBZ31834.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBZ31834.1 - 0.14 12.7 0.1 0.29 11.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 CBZ31834.1 - 0.15 11.3 0.1 0.31 10.2 0.1 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CBZ31834.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 CBZ31834.1 - 0.17 11.6 0.0 0.74 9.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CBZ31834.1 - 0.21 11.2 0.0 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Rotamase PF00639.21 CBZ31835.1 - 4.2e-21 75.7 0.0 4.7e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CBZ31835.1 - 9.2e-17 61.7 0.0 1.1e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CBZ31835.1 - 0.01 16.7 0.0 0.012 16.4 0.0 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Exonuc_VII_S PF02609.16 CBZ31835.1 - 0.071 13.2 0.1 0.25 11.4 0.1 1.8 2 0 0 2 2 2 0 Exonuclease VII small subunit FA_desaturase PF00487.24 CBZ31836.1 - 6.3e-39 134.3 20.1 9e-39 133.8 20.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBZ31836.1 - 0.00014 21.9 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAM199X PF15814.5 CBZ31837.1 - 4.1 6.4 7.9 2.3 7.2 0.8 2.1 2 0 0 2 2 2 0 Protein family FAM199X Inj_translocase PF16928.5 CBZ31839.1 - 0.045 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Com_YlbF PF06133.11 CBZ31839.1 - 0.49 11.0 3.5 16 6.2 0.3 3.2 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA VWA_2 PF13519.6 CBZ31840.1 - 1.6e-12 48.0 0.1 1.1e-11 45.3 0.0 2.2 1 1 1 2 2 2 1 von Willebrand factor type A domain UIM PF02809.20 CBZ31840.1 - 5.2e-07 29.2 11.2 0.00023 20.8 3.8 3.3 2 0 0 2 2 2 2 Ubiquitin interaction motif VWA PF00092.28 CBZ31840.1 - 0.0013 19.0 0.2 0.002 18.4 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Methyltransf_33 PF10017.9 CBZ31840.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.3 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Ssl1 PF04056.14 CBZ31840.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Ssl1-like MMR_HSR1 PF01926.23 CBZ31841.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ31841.1 - 0.098 12.2 0.1 0.17 11.4 0.1 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B PMSR PF01625.21 CBZ31842.1 - 7.2e-53 178.9 1.0 8.8e-53 178.6 1.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Chorein_N PF12624.7 CBZ31843.1 - 2.6e-07 30.7 0.1 1.2e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CBZ31843.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal LolB PF03550.14 CBZ31843.1 - 0.17 11.9 0.0 0.5 10.4 0.0 1.7 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB Aa_trans PF01490.18 CBZ31844.1 - 3.7e-58 197.2 23.6 4.2e-58 197.0 23.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ31844.1 - 2.7e-10 39.9 10.5 2.7e-10 39.9 10.5 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family SMC_N PF02463.19 CBZ31845.1 - 5.5e-63 212.3 0.0 8.6e-63 211.7 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBZ31845.1 - 1e-23 83.9 0.0 3.3e-23 82.2 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CBZ31845.1 - 1.1e-17 65.2 1.7 1.1e-17 65.2 1.7 5.5 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 CBZ31845.1 - 1.6e-14 54.4 16.2 1.5e-12 48.0 8.7 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 CBZ31845.1 - 3.4e-14 53.4 0.1 8e-06 25.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBZ31845.1 - 0.0034 17.1 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CBZ31845.1 - 0.066 13.7 19.0 0.54 10.8 0.0 5.5 3 2 0 3 3 3 0 ABC transporter Myb_DNA-binding PF00249.31 CBZ31845.1 - 0.13 12.4 1.4 0.51 10.6 1.4 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF4250 PF14056.6 CBZ31845.1 - 0.82 9.7 10.5 0.39 10.7 0.1 4.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4250) ChuX_HutX PF06228.13 CBZ31846.1 - 0.048 13.4 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX Synaptobrevin PF00957.21 CBZ31847.1 - 1.8e-30 104.5 4.9 3.1e-30 103.8 4.9 1.4 1 0 0 1 1 1 1 Synaptobrevin FtsK_SpoIIIE PF01580.18 CBZ31847.1 - 0.03 13.7 0.3 0.047 13.0 0.3 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF4844 PF16133.5 CBZ31847.1 - 0.062 13.8 1.1 0.16 12.6 0.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4844) Baculo_11_kDa PF06143.11 CBZ31847.1 - 2.1 8.0 7.2 4.5 6.9 6.9 1.7 1 1 0 1 1 1 0 Baculovirus 11 kDa family GST_C_2 PF13410.6 CBZ31849.1 - 0.027 14.5 0.0 0.033 14.2 0.0 1.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain His_Phos_1 PF00300.22 CBZ31850.1 - 3.1e-40 138.0 0.0 3.4e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ASCH PF04266.14 CBZ31851.1 - 9.8e-17 61.5 0.1 6.1e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 ASCH domain zf-C2HC5 PF06221.13 CBZ31851.1 - 0.00012 21.9 9.4 0.00032 20.6 9.4 1.7 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Siva PF05458.12 CBZ31851.1 - 0.08 12.6 3.2 0.21 11.2 1.7 2.4 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Ku_C PF03730.14 CBZ31851.1 - 1.3 9.8 4.3 28 5.5 0.2 3.3 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm DEAD PF00270.29 CBZ31852.1 - 1.4e-38 132.4 0.0 2.2e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ31852.1 - 2.1e-22 79.5 0.0 6.5e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ31852.1 - 8.4e-06 25.9 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ31852.1 - 0.00041 20.6 0.0 0.0014 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain SecA_DEAD PF07517.14 CBZ31852.1 - 0.015 14.6 0.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain Adaptin_N PF01602.20 CBZ31853.1 - 1.8e-79 267.7 0.0 2.3e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBZ31853.1 - 3.8e-10 40.0 0.0 2.4e-06 27.7 0.0 2.4 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ31853.1 - 0.00021 21.6 2.7 1.2 9.5 0.2 4.2 3 1 1 4 4 4 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CBZ31853.1 - 0.0097 16.5 0.0 0.25 11.9 0.0 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 CBZ31853.1 - 0.025 14.7 0.0 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT PF02985.22 CBZ31853.1 - 0.078 13.3 10.1 2.7 8.5 0.1 5.6 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 CBZ31853.1 - 0.29 11.7 10.1 0.29 11.7 0.1 4.7 6 0 0 6 6 6 0 HEAT-like repeat DSPc PF00782.20 CBZ31854.1 - 2.3e-28 98.6 0.0 4.6e-28 97.7 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 CBZ31854.1 - 0.0014 18.2 0.1 1.6 8.3 0.0 3.0 3 0 0 3 3 3 2 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBZ31854.1 - 0.029 13.9 0.1 0.063 12.8 0.0 1.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CBZ31854.1 - 0.091 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate CDC37_M PF08565.11 CBZ31854.1 - 0.095 12.6 0.2 1.4 8.9 0.0 2.5 3 0 0 3 3 3 0 Cdc37 Hsp90 binding domain SCP-1 PF05483.12 CBZ31855.1 - 0.002 16.3 5.7 0.0034 15.5 5.7 1.3 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) Cnn_1N PF07989.11 CBZ31855.1 - 0.033 14.3 0.9 0.033 14.3 0.9 3.0 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 CorA PF01544.18 CBZ31855.1 - 0.11 11.8 5.5 0.22 10.8 5.5 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein AATF-Che1 PF13339.6 CBZ31855.1 - 0.16 12.7 7.4 1.2 9.8 0.5 3.8 3 1 1 4 4 4 0 Apoptosis antagonizing transcription factor GAS PF13851.6 CBZ31855.1 - 0.36 10.1 11.5 0.44 9.9 5.5 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Seryl_tRNA_N PF02403.22 CBZ31855.1 - 0.37 11.1 7.9 1.5 9.1 2.8 3.0 2 1 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain HALZ PF02183.18 CBZ31855.1 - 0.51 10.6 6.2 0.85 9.9 0.1 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper CtIP_N PF10482.9 CBZ31855.1 - 0.81 9.7 6.7 2.1 8.4 6.7 1.7 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain Spc7 PF08317.11 CBZ31855.1 - 0.94 8.3 14.7 0.99 8.2 5.5 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 CBZ31855.1 - 1.1 9.5 12.9 1.2 9.4 10.9 2.1 2 1 0 2 2 1 0 JNK_SAPK-associated protein-1 DUF4472 PF14739.6 CBZ31855.1 - 1.3 9.7 8.5 0.96 10.2 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Rx_N PF18052.1 CBZ31855.1 - 2.3 8.6 9.0 4.3 7.7 6.2 2.8 2 1 0 2 2 2 0 Rx N-terminal domain Macoilin PF09726.9 CBZ31855.1 - 2.8 6.4 7.4 4.4 5.7 7.4 1.3 1 0 0 1 1 1 0 Macoilin family BLOC1_2 PF10046.9 CBZ31855.1 - 3.2 8.1 8.2 2.6 8.4 1.4 3.2 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.11 CBZ31855.1 - 3.7 7.3 10.2 0.89 9.4 6.3 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 ZapB PF06005.12 CBZ31855.1 - 3.9 8.0 9.4 20 5.7 6.6 3.4 2 1 0 2 2 2 0 Cell division protein ZapB COG2 PF06148.11 CBZ31855.1 - 7.6 6.6 7.2 3.7 7.6 0.6 3.0 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FYVE_2 PF02318.16 CBZ31857.1 - 0.00028 21.1 7.5 0.00055 20.1 7.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger EF-hand_6 PF13405.6 CBZ31858.1 - 0.0049 16.7 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBZ31858.1 - 0.063 12.9 0.0 0.29 10.8 0.0 2.1 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 CBZ31858.1 - 0.11 13.0 0.1 0.36 11.3 0.1 1.8 1 1 0 1 1 1 0 EF-hand domain pair ERCC4 PF02732.15 CBZ31859.1 - 6.9e-16 58.8 0.0 3.5e-15 56.6 0.0 2.1 2 0 0 2 2 2 1 ERCC4 domain PIG-H PF10181.9 CBZ31860.1 - 1.9e-10 40.4 0.2 3.3e-10 39.7 0.2 1.4 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component LRR_4 PF12799.7 CBZ31862.1 - 3e-08 33.8 4.4 0.26 11.8 0.0 7.1 6 2 2 8 8 8 2 Leucine Rich repeats (2 copies) DUF4805 PF16063.5 CBZ31862.1 - 0.035 13.4 3.9 0.059 12.7 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) LRR_8 PF13855.6 CBZ31862.1 - 0.17 11.7 6.9 33 4.3 0.4 5.3 6 1 0 6 6 6 0 Leucine rich repeat Hexapep PF00132.24 CBZ31863.1 - 1.1e-13 50.4 3.2 0.002 17.8 0.0 3.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CBZ31863.1 - 0.039 13.7 8.2 0.064 13.0 2.2 3.2 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF4915 PF16261.5 CBZ31863.1 - 0.067 12.4 0.0 1.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4915) HECT_2 PF09814.9 CBZ31863.1 - 0.14 11.0 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding PDR_CDR PF06422.12 CBZ31864.1 - 0.037 13.9 0.3 2 8.4 0.0 2.7 2 0 0 2 2 2 0 CDR ABC transporter Exo_endo_phos PF03372.23 CBZ31865.1 - 2.1e-14 53.6 0.0 4e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3301 PF11743.8 CBZ31865.1 - 0.04 13.6 0.6 0.9 9.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) ThiF PF00899.21 CBZ31867.1 - 6e-57 192.8 0.0 6.1e-56 189.5 0.0 2.3 1 1 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 CBZ31867.1 - 1.4e-20 73.7 0.0 2.3e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 CBZ31867.1 - 1.4e-05 25.2 0.0 0.0092 15.9 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 CBZ31867.1 - 0.045 14.2 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding ABC1 PF03109.16 CBZ31868.1 - 1.3e-27 96.3 0.0 2.6e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 CBZ31868.1 - 6.8e-05 22.9 0.4 0.00024 21.1 0.4 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CBZ31868.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Ribosomal_L9_N PF01281.19 CBZ31869.1 - 3.2e-06 26.6 0.0 6.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Sperm_Ag_HE2 PF05324.13 CBZ31870.1 - 0.28 11.7 4.3 0.29 11.6 4.3 1.1 1 0 0 1 1 1 0 Sperm antigen HE2 JHY PF15261.6 CBZ31871.1 - 2.3e-06 28.3 1.0 0.1 13.3 0.0 2.9 2 1 0 2 2 2 2 Jhy protein Ribosomal_L2_C PF03947.18 CBZ31873.1 - 3.4e-21 75.7 0.1 5.6e-21 75.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Sod_Fe_C PF02777.18 CBZ31874.1 - 3.6e-35 120.2 0.4 1.8e-34 118.0 0.0 2.2 3 1 0 3 3 3 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBZ31874.1 - 2.8e-20 72.6 0.2 6.8e-20 71.3 0.2 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Isochorismatase PF00857.20 CBZ31875.1 - 7e-13 49.1 0.0 4.6e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 CBZ31876.1 - 3.4e-10 40.4 0.1 6.9e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 CBZ31877.1 - 1.1e-12 48.5 0.2 5e-12 46.4 0.2 1.8 1 1 0 1 1 1 1 Isochorismatase family zf-Tim10_DDP PF02953.15 CBZ31878.1 - 3.3e-12 45.9 0.1 4.7e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Disintegrin PF00200.23 CBZ31880.1 - 0.87 10.4 6.7 0.28 12.0 1.0 2.6 2 0 0 2 2 2 0 Disintegrin M_domain PF12938.7 CBZ31881.1 - 0.0044 16.9 0.4 0.0044 16.9 0.4 2.3 2 0 0 2 2 2 1 M domain of GW182 VWA_2 PF13519.6 CBZ31881.1 - 0.16 12.6 0.3 0.71 10.6 0.3 2.1 1 0 0 1 1 1 0 von Willebrand factor type A domain APG6 PF04111.12 CBZ31885.1 - 9.3e-15 55.0 0.0 1.5e-05 25.1 0.0 3.7 3 1 0 3 3 3 3 Apg6 BARA domain WD40 PF00400.32 CBZ31886.1 - 1.1e-22 79.9 19.2 6.2e-06 26.9 0.1 10.5 10 1 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ31886.1 - 1.2e-14 54.4 0.7 0.0068 16.7 0.0 6.5 5 2 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBZ31886.1 - 0.00041 19.8 0.1 0.18 11.1 0.0 4.0 4 1 1 5 5 5 1 WD40-like domain PQQ_2 PF13360.6 CBZ31886.1 - 0.00049 19.8 3.2 0.00059 19.5 0.3 2.6 3 0 0 3 3 3 1 PQQ-like domain BBS2_Mid PF14783.6 CBZ31886.1 - 0.00077 19.5 0.1 0.59 10.2 0.0 4.5 6 1 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 CBZ31886.1 - 0.0017 17.1 3.3 0.86 8.2 0.1 4.2 3 2 1 5 5 5 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 CBZ31886.1 - 0.0094 15.3 0.9 0.29 10.4 0.0 3.2 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus eIF-6 PF01912.18 CBZ31887.1 - 0.22 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 eIF-6 family U1snRNP70_N PF12220.8 CBZ31888.1 - 3.6 8.3 7.0 2.9 8.6 0.4 3.5 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal OAD_gamma PF04277.13 CBZ31888.1 - 9.8 6.8 10.0 0.7 10.5 4.1 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S24 PF00717.23 CBZ31890.1 - 1.5e-10 40.9 0.1 2.5e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase S24-like Rad60-SLD PF11976.8 CBZ31892.1 - 2.6e-25 88.1 0.1 3.2e-25 87.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBZ31892.1 - 3.4e-11 42.7 0.0 4.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family HTH_41 PF14502.6 CBZ31892.1 - 0.13 11.9 0.2 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain XET_C PF06955.12 CBZ31893.1 - 2.7 7.9 4.9 0.79 9.6 1.1 2.1 2 0 0 2 2 2 0 Xyloglucan endo-transglycosylase (XET) C-terminus Spt20 PF12090.8 CBZ31895.1 - 0.27 10.8 2.5 0.39 10.3 2.5 1.2 1 0 0 1 1 1 0 Spt20 family MAP65_ASE1 PF03999.12 CBZ31895.1 - 1 8.0 5.1 1.4 7.6 5.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Pribosyl_synth PF14572.6 CBZ31896.1 - 3.3e-21 76.1 2.9 5.4e-21 75.4 0.2 2.4 3 0 0 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CBZ31896.1 - 4.7e-18 65.2 0.8 2e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase SPX PF03105.19 CBZ31896.1 - 6.7e-05 23.0 2.9 6.7e-05 23.0 2.9 2.5 2 1 1 3 3 3 1 SPX domain Pribosyltran PF00156.27 CBZ31896.1 - 0.00067 19.2 0.0 0.0099 15.4 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Pkinase_Tyr PF07714.17 CBZ31897.1 - 1.8e-07 30.7 0.0 0.0013 18.1 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CBZ31897.1 - 1.5e-06 27.8 0.0 0.034 13.5 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain SUIM_assoc PF16619.5 CBZ31897.1 - 0.014 15.5 0.0 1.1 9.3 0.0 4.0 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 CBZ31898.1 - 1.9e-36 125.8 0.0 1.3e-12 47.7 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31898.1 - 5.4e-16 58.7 0.0 2.7e-06 26.9 0.0 3.3 3 1 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 CBZ31898.1 - 0.0093 15.9 0.1 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Complex1_LYR PF05347.15 CBZ31899.1 - 0.0017 18.3 2.4 0.0098 15.9 0.8 2.6 3 0 0 3 3 3 1 Complex 1 protein (LYR family) CMAS PF02353.20 CBZ31900.1 - 2.8e-74 249.9 0.0 3.8e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CBZ31900.1 - 6.1e-18 65.3 0.0 8e-17 61.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ31900.1 - 3.8e-13 49.9 0.0 1.7e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ31900.1 - 6.6e-12 45.6 0.0 1.4e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ31900.1 - 3.1e-09 37.5 0.0 3.5e-08 34.1 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain MTS PF05175.14 CBZ31900.1 - 6.6e-06 25.8 0.0 3.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CBZ31900.1 - 8.2e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CBZ31900.1 - 0.00064 18.9 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 CBZ31900.1 - 0.001 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 CBZ31900.1 - 0.001 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) FtsJ PF01728.19 CBZ31900.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 CBZ31900.1 - 0.0014 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CBZ31900.1 - 0.0025 17.8 0.0 0.0046 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CBZ31900.1 - 0.022 14.2 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB eIF-5_eIF-2B PF01873.17 CBZ31901.1 - 3.6e-29 101.0 0.7 6.8e-29 100.1 0.7 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Cytochrom_c3_2 PF14537.6 CBZ31901.1 - 0.049 14.1 0.4 0.21 12.1 0.4 2.1 1 0 0 1 1 1 0 Cytochrome c3 Img2 PF05046.14 CBZ31902.1 - 1.2e-05 25.5 0.0 1.9e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Miga PF10265.9 CBZ31904.1 - 0.04 12.9 0.0 0.046 12.7 0.0 1.0 1 0 0 1 1 1 0 Mitoguardin ASFV_J13L PF05568.11 CBZ31904.1 - 0.051 13.3 0.1 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein Mtp PF03821.16 CBZ31904.1 - 0.091 12.3 0.3 0.12 12.0 0.3 1.1 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter ATG27 PF09451.10 CBZ31904.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF4079 PF13301.6 CBZ31904.1 - 0.33 11.1 3.2 0.19 11.9 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) TMEM154 PF15102.6 CBZ31904.1 - 0.33 10.9 2.5 0.47 10.4 0.1 1.9 1 1 1 2 2 2 0 TMEM154 protein family TNFR_16_TM PF18422.1 CBZ31904.1 - 0.6 10.1 4.8 1 9.3 4.8 1.3 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Vpu PF00558.19 CBZ31904.1 - 1 9.2 2.4 1.8 8.4 2.4 1.3 1 0 0 1 1 1 0 Vpu protein OATP PF03137.20 CBZ31906.1 - 0.00023 19.6 0.0 0.00027 19.4 0.0 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF4736 PF15883.5 CBZ31906.1 - 0.0026 17.5 0.3 0.0072 16.1 0.3 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4736) Phage_holin_3_6 PF07332.11 CBZ31906.1 - 0.0033 17.5 5.6 0.0088 16.1 5.6 1.6 1 1 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Yip1 PF04893.17 CBZ31906.1 - 0.0041 16.9 0.3 0.0053 16.5 0.3 1.1 1 0 0 1 1 1 1 Yip1 domain Oxidored_q3 PF00499.20 CBZ31906.1 - 0.0072 16.1 0.8 0.01 15.6 0.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 HemY_N PF07219.13 CBZ31906.1 - 0.017 15.3 0.6 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 HemY protein N-terminus UPF0370 PF13980.6 CBZ31906.1 - 0.017 15.1 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) DUF3357 PF11837.8 CBZ31906.1 - 0.025 15.0 1.7 0.66 10.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) BPD_transp_2 PF02653.16 CBZ31906.1 - 0.031 13.4 0.6 0.031 13.4 0.6 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component Peptidase_U4 PF03419.13 CBZ31906.1 - 0.033 13.5 0.1 0.04 13.2 0.1 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Prominin PF05478.11 CBZ31906.1 - 0.093 10.7 0.2 0.12 10.3 0.2 1.1 1 0 0 1 1 1 0 Prominin DUF4381 PF14316.6 CBZ31906.1 - 0.11 12.8 0.4 0.2 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Trp_oprn_chp PF09534.10 CBZ31906.1 - 0.11 12.3 1.5 3 7.6 0.8 1.9 1 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FAM176 PF14851.6 CBZ31906.1 - 0.12 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 FAM176 family Neur_chan_memb PF02932.16 CBZ31906.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4131 PF13567.6 CBZ31906.1 - 0.13 11.9 3.0 0.63 9.7 3.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) QCR10 PF09796.9 CBZ31906.1 - 0.15 12.1 2.3 0.37 10.9 2.3 1.6 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4307 PF14155.6 CBZ31906.1 - 0.16 11.8 0.3 4.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) DUF3290 PF11694.8 CBZ31906.1 - 0.16 11.9 0.8 0.25 11.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF898 PF05987.13 CBZ31906.1 - 0.18 10.8 3.2 0.11 11.6 0.6 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) EphA2_TM PF14575.6 CBZ31906.1 - 0.21 12.5 0.4 0.33 11.8 0.0 1.6 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 CBZ31906.1 - 0.22 11.4 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Spore_YhaL PF14147.6 CBZ31906.1 - 0.22 11.2 2.1 0.4 10.4 2.1 1.3 1 0 0 1 1 1 0 Sporulation protein YhaL FA_desaturase PF00487.24 CBZ31906.1 - 0.31 10.9 4.3 1.5 8.6 4.3 1.9 1 1 0 1 1 1 0 Fatty acid desaturase FtsX PF02687.21 CBZ31906.1 - 0.85 10.1 5.6 1.5 9.3 5.6 1.4 1 1 0 1 1 1 0 FtsX-like permease family CitMHS PF03600.16 CBZ31906.1 - 1.7 7.7 4.0 2.9 7.0 4.0 1.3 1 1 0 1 1 1 0 Citrate transporter Amastin PF07344.11 CBZ31909.1 - 3.4e-06 27.0 7.4 6.2e-06 26.1 7.4 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein Pox_A14 PF05767.12 CBZ31909.1 - 0.078 13.1 1.2 0.19 11.9 1.2 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DnaJ PF00226.31 CBZ31910.1 - 1.2e-15 57.3 0.2 2.7e-15 56.2 0.2 1.6 1 1 0 1 1 1 1 DnaJ domain Pkinase PF00069.25 CBZ31911.1 - 1.1e-16 61.0 0.0 2.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31911.1 - 2.8e-11 43.2 0.0 9e-11 41.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 CBZ31911.1 - 0.027 13.5 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Amastin PF07344.11 CBZ31912.1 - 1.6e-55 187.2 10.7 1.9e-55 187.0 10.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1467 PF07330.12 CBZ31912.1 - 0.022 14.7 4.5 1.3 9.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) Clc-like PF07062.12 CBZ31912.1 - 4.9 6.6 10.3 0.28 10.6 4.7 1.6 2 0 0 2 2 2 0 Clc-like Amastin PF07344.11 CBZ31913.1 - 1.6e-55 187.2 10.7 1.9e-55 187.0 10.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1467 PF07330.12 CBZ31913.1 - 0.022 14.7 4.5 1.3 9.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1467) Clc-like PF07062.12 CBZ31913.1 - 4.9 6.6 10.3 0.28 10.6 4.7 1.6 2 0 0 2 2 2 0 Clc-like Amastin PF07344.11 CBZ31914.1 - 2.8e-55 186.4 8.4 3.3e-55 186.2 8.4 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein AAA_16 PF13191.6 CBZ31915.1 - 3.9e-07 30.6 0.4 1.4e-06 28.8 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CBZ31915.1 - 0.00042 20.6 0.3 0.011 16.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 CBZ31915.1 - 0.00088 19.3 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CBZ31915.1 - 0.0027 17.7 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CBZ31915.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CBZ31915.1 - 0.019 14.1 0.0 0.041 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) cobW PF02492.19 CBZ31915.1 - 0.09 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Oleosin PF01277.17 CBZ31915.1 - 0.33 10.7 0.0 0.33 10.7 0.0 2.3 3 0 0 3 3 3 0 Oleosin AAA_16 PF13191.6 CBZ31916.1 - 0.00072 20.0 0.1 0.0024 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 CBZ31916.1 - 0.039 13.8 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 CBZ31916.1 - 0.099 12.0 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC Ub-Mut7C PF14451.6 CBZ31916.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Mut7-C ubiquitin DUF2624 PF11116.8 CBZ31916.1 - 0.12 13.3 0.1 0.25 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2624) Amastin PF07344.11 CBZ31919.1 - 2.4e-56 189.9 9.4 2.9e-56 189.6 9.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF2207 PF09972.9 CBZ31919.1 - 0.0056 15.5 1.4 0.0065 15.3 0.8 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 CBZ31919.1 - 1.7 8.7 9.4 0.37 10.9 3.5 2.3 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Amastin PF07344.11 CBZ31920.1 - 3.7e-21 75.6 4.0 4.5e-21 75.3 4.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1218 PF06749.12 CBZ31920.1 - 0.38 11.3 4.5 0.29 11.7 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) CotJB PF12652.7 CBZ31922.1 - 0.032 14.4 11.2 0.46 10.7 4.3 4.4 3 1 1 4 4 4 0 CotJB protein Terminase_4 PF05119.12 CBZ31922.1 - 0.17 12.3 1.3 0.71 10.3 0.4 2.4 2 1 0 2 2 2 0 Phage terminase, small subunit DUF1178 PF06676.11 CBZ31922.1 - 0.55 10.6 9.6 1.2 9.6 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1178) SET PF00856.28 CBZ31923.1 - 1.5e-09 38.5 0.0 6.1e-08 33.2 0.0 3.1 1 1 0 1 1 1 1 SET domain Phage_holin_3_5 PF16085.5 CBZ31923.1 - 0.14 12.3 0.3 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage holin Hol, superfamily III SR-25 PF10500.9 CBZ31923.1 - 4.1 7.0 7.0 7 6.2 1.2 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DNA_pol_B_thumb PF14791.6 CBZ31924.1 - 8.9e-21 73.8 0.0 1.9e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 CBZ31924.1 - 2.6e-17 63.0 0.0 5.7e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 CBZ31924.1 - 4.1e-14 52.7 0.2 2.1e-12 47.2 0.1 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CBZ31924.1 - 2.2e-13 49.8 0.0 1.9e-12 46.8 0.0 2.5 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 CBZ31924.1 - 6.9e-05 23.4 0.1 0.0041 17.7 0.0 2.7 1 1 2 3 3 3 1 Helix-hairpin-helix domain HHH_3 PF12836.7 CBZ31924.1 - 0.045 14.0 0.2 8.1 6.8 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix motif DMP12 PF16779.5 CBZ31924.1 - 0.06 13.3 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA-mimic protein DNA_pol_B_palm PF14792.6 CBZ31925.1 - 2.3e-26 92.2 0.0 5.5e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 CBZ31925.1 - 3.2e-16 59.2 1.0 1.8e-14 53.6 0.8 3.2 2 1 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 CBZ31925.1 - 5.7e-09 35.7 0.0 3.3e-08 33.2 0.0 2.2 1 1 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 CBZ31925.1 - 0.0003 21.3 0.1 0.0034 18.0 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 CBZ31925.1 - 0.014 15.6 0.0 0.037 14.3 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Lactamase_B_4 PF13691.6 CBZ31926.1 - 1.2e-05 24.9 0.0 3.4e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CBZ31926.1 - 0.0051 16.4 0.5 0.015 14.9 0.4 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBZ31926.1 - 0.063 13.3 0.6 0.19 11.7 0.2 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily PKS_DE PF18369.1 CBZ31928.1 - 0.37 11.4 6.3 0.13 12.9 1.3 2.6 2 0 0 2 2 2 0 Polyketide synthase dimerisation element domain HTH_37 PF13744.6 CBZ31930.1 - 0.042 13.8 0.5 0.042 13.8 0.5 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Dpy-30 PF05186.13 CBZ31931.1 - 1.5e-06 27.8 0.1 3.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Dpy-30 motif Med30 PF11315.8 CBZ31931.1 - 0.011 16.0 0.7 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Mediator complex subunit 30 TMEM65 PF10507.9 CBZ31932.1 - 2.8e-30 104.5 1.1 1.1e-29 102.5 1.1 2.1 1 0 0 1 1 1 1 Transmembrane protein 65 DUF1993 PF09351.10 CBZ31932.1 - 0.38 10.9 1.4 0.66 10.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) DnaJ PF00226.31 CBZ31934.1 - 9e-17 61.0 3.4 3.1e-08 33.6 0.1 3.0 2 1 1 3 3 3 2 DnaJ domain MMPL PF03176.15 CBZ31934.1 - 0.035 13.0 0.2 0.069 12.1 0.2 1.4 1 0 0 1 1 1 0 MMPL family DUF5401 PF17380.2 CBZ31934.1 - 0.89 7.6 13.3 1.2 7.1 13.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Peptidase_C1 PF00112.23 CBZ31937.1 - 2.8e-73 246.6 1.0 3.7e-73 246.2 1.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBZ31937.1 - 7.3e-11 42.3 0.7 1.1e-10 41.7 0.7 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBZ31937.1 - 5.1e-07 28.8 0.5 0.0004 19.3 0.1 2.4 2 0 0 2 2 2 2 Peptidase C1-like family Hist_deacetyl PF00850.19 CBZ31938.1 - 1.6e-58 198.6 0.0 2.9e-58 197.8 0.0 1.4 1 1 0 1 1 1 1 Histone deacetylase domain zf-RING_2 PF13639.6 CBZ31939.1 - 6.5e-09 36.0 5.8 6.5e-09 36.0 5.8 4.2 4 0 0 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ31939.1 - 0.00016 21.5 5.4 0.00016 21.5 5.4 4.4 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ31939.1 - 0.00023 21.0 4.1 0.00023 21.0 4.1 4.5 4 2 0 4 4 4 1 zinc-RING finger domain zf-HC5HC2H PF13771.6 CBZ31939.1 - 0.00058 20.1 2.3 0.00058 20.1 2.3 4.3 2 1 3 5 5 5 2 PHD-like zinc-binding domain zf-C3HC4_3 PF13920.6 CBZ31939.1 - 0.00098 18.9 6.4 0.00098 18.9 6.4 4.9 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBZ31939.1 - 0.0018 18.0 7.1 0.0018 18.0 7.1 3.5 3 0 0 3 3 3 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 CBZ31939.1 - 0.0045 16.6 3.5 0.0045 16.6 3.5 4.1 3 1 0 3 3 3 1 Zinc-ribbon, C4HC2 type TPR_1 PF00515.28 CBZ31941.1 - 6.7e-54 177.6 34.8 5e-08 32.4 0.0 9.5 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ31941.1 - 7e-45 147.6 30.0 1.7e-05 24.6 0.1 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ31941.1 - 2e-30 104.2 29.7 6.3e-07 29.0 0.1 9.1 5 3 4 9 9 9 7 TPR repeat STI1 PF17830.1 CBZ31941.1 - 7.4e-29 99.5 5.3 1.7e-14 53.5 1.2 3.5 3 0 0 3 3 3 2 STI1 domain TPR_8 PF13181.6 CBZ31941.1 - 6.9e-24 82.0 22.4 0.00047 20.2 0.0 8.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ31941.1 - 3.4e-20 72.1 21.1 6.4e-08 32.8 1.1 7.4 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ31941.1 - 9.4e-18 64.6 7.6 0.00085 19.9 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ31941.1 - 1.3e-16 59.9 8.2 0.19 12.6 0.0 9.4 5 3 5 10 10 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ31941.1 - 1.2e-15 57.7 8.9 0.12 12.9 0.1 6.8 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ31941.1 - 1.6e-11 43.4 13.2 0.046 13.8 0.1 8.7 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ31941.1 - 1.9e-11 43.5 18.5 0.25 11.8 0.3 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ31941.1 - 2.5e-10 40.3 0.0 0.00087 19.4 0.0 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ31941.1 - 1.9e-08 33.9 22.1 0.015 15.1 0.0 8.7 10 0 0 10 10 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ31941.1 - 7.3e-08 32.4 4.2 1.2 9.3 0.0 6.3 7 0 0 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CBZ31941.1 - 1.1e-05 25.5 25.6 0.3 11.3 1.5 6.3 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBZ31941.1 - 0.00018 21.9 21.6 6.1 7.7 0.2 9.2 9 0 0 9 9 9 1 Tetratricopeptide repeat MIT PF04212.18 CBZ31941.1 - 0.0002 21.3 24.0 0.83 9.8 0.8 7.8 7 1 1 8 8 8 2 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 CBZ31941.1 - 0.00045 19.6 10.3 1.1 8.8 0.0 6.1 7 0 0 7 7 7 1 SHNi-TPR TPR_20 PF14561.6 CBZ31941.1 - 0.0017 18.7 1.6 2.4 8.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CBZ31941.1 - 0.014 15.4 15.1 0.17 11.9 0.1 4.8 3 2 0 4 4 4 0 Putative TPR-like repeat DUF3808 PF10300.9 CBZ31941.1 - 0.016 14.0 2.3 0.096 11.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) BTAD PF03704.17 CBZ31941.1 - 0.023 15.1 5.7 0.74 10.2 0.3 4.4 3 2 2 5 5 5 0 Bacterial transcriptional activator domain TPM_phosphatase PF04536.14 CBZ31941.1 - 0.031 14.4 2.8 2.6 8.2 0.1 4.0 3 1 0 3 3 3 0 TPM domain DUF3856 PF12968.7 CBZ31941.1 - 0.049 13.7 8.8 5.2 7.1 0.1 5.4 3 3 1 5 5 5 0 Domain of Unknown Function (DUF3856) DnaI_N PF07319.11 CBZ31941.1 - 0.19 12.4 4.7 1.9 9.2 0.1 4.1 4 1 1 5 5 4 0 Primosomal protein DnaI N-terminus TPR_3 PF07720.12 CBZ31941.1 - 1.3 9.1 25.8 18 5.5 0.4 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 CBZ31941.1 - 2 8.1 9.7 2 8.1 1.9 3.6 1 1 2 3 3 3 0 26S proteasome subunit RPN7 DUF1126 PF06565.12 CBZ31942.1 - 7.5e-62 205.7 0.0 9.7e-26 89.6 0.0 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_1 PF00036.32 CBZ31942.1 - 0.0014 18.0 0.0 0.0062 16.0 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 CBZ31942.1 - 0.0061 16.0 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CBZ31942.1 - 0.037 14.0 0.0 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 CBZ31942.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair Pribosyltran_N PF13793.6 CBZ31943.1 - 6.8e-35 119.5 0.1 1.3e-34 118.6 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBZ31943.1 - 1.9e-23 83.5 0.3 7.5e-23 81.5 0.2 1.9 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBZ31943.1 - 6.4e-19 68.0 0.1 1.1e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBZ31943.1 - 0.0042 16.5 0.1 0.0077 15.7 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ZnuA PF01297.17 CBZ31943.1 - 0.17 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Granulin PF00396.18 CBZ31944.1 - 0.37 11.2 3.4 1.3 9.4 3.4 1.9 1 0 0 1 1 1 0 Granulin Sec3_C PF09763.9 CBZ31945.1 - 3.1e-78 263.9 2.7 1.1e-38 133.2 0.2 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec3 DUF812 PF05667.11 CBZ31945.1 - 0.0019 17.2 4.4 0.0036 16.3 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Vps54_N PF10475.9 CBZ31945.1 - 0.054 12.8 3.8 0.11 11.7 3.8 1.4 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Fzo_mitofusin PF04799.13 CBZ31945.1 - 0.26 10.8 9.4 6.5 6.3 6.8 2.7 1 1 1 2 2 2 0 fzo-like conserved region TPMT PF05724.11 CBZ31946.1 - 1.6e-16 60.7 0.0 3.2e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 CBZ31946.1 - 0.00049 20.0 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ31946.1 - 0.031 15.0 0.0 0.059 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain mTERF PF02536.14 CBZ31947.1 - 4.6e-05 22.5 0.0 0.00081 18.4 0.0 2.1 1 1 1 2 2 2 2 mTERF Slu7 PF11708.8 CBZ31948.1 - 3.6e-05 23.6 4.0 7.5e-05 22.6 2.6 2.1 2 1 1 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_3 PF13917.6 CBZ31948.1 - 0.0032 17.4 0.7 0.0093 15.9 0.7 1.8 1 0 0 1 1 1 1 Zinc knuckle BTK PF00779.19 CBZ31948.1 - 0.068 13.0 2.2 0.14 12.0 2.2 1.5 1 0 0 1 1 1 0 BTK motif ANAPC4_WD40 PF12894.7 CBZ31949.1 - 5.3e-10 39.5 0.7 1.8e-05 24.9 0.0 5.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBZ31949.1 - 1.9e-08 33.8 2.6 0.0017 17.5 0.2 4.2 5 0 0 5 5 5 2 Coatomer WD associated region TPR_7 PF13176.6 CBZ31949.1 - 0.00029 20.7 7.3 0.081 13.0 0.4 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-RanBP PF00641.18 CBZ31949.1 - 0.0059 15.9 10.2 0.013 14.8 2.8 2.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others WD40 PF00400.32 CBZ31949.1 - 0.01 16.7 11.4 1.3 10.0 0.0 5.8 6 0 0 6 6 5 0 WD domain, G-beta repeat Vps39_1 PF10366.9 CBZ31949.1 - 0.064 13.6 0.3 0.22 11.8 0.3 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 CBZ31949.1 - 0.091 12.6 6.6 1.2 9.1 0.2 4.0 3 1 2 5 5 4 0 Region in Clathrin and VPS eIF2A PF08662.11 CBZ31949.1 - 0.093 12.6 0.1 0.64 9.9 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A TPR_12 PF13424.6 CBZ31949.1 - 0.14 12.5 17.6 0.29 11.5 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 CBZ31949.1 - 0.16 11.7 2.3 3.7 7.2 0.1 3.1 2 1 1 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 CBZ31949.1 - 1.4 9.7 3.7 12 6.8 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ31949.1 - 1.5 9.2 20.5 0.86 9.9 1.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DZR PF12773.7 CBZ31949.1 - 2.8 8.0 13.2 66 3.6 13.2 2.7 1 1 0 1 1 1 0 Double zinc ribbon TPR_16 PF13432.6 CBZ31949.1 - 4.2 8.1 14.2 27 5.5 1.6 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MIX PF18529.1 CBZ31950.1 - 1.1e-93 310.8 0.9 1.3e-93 310.6 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial membrane-anchored proteins Alpha_GJ PF03229.13 CBZ31951.1 - 8.5 7.0 7.8 1.6 9.3 2.4 2.2 1 1 1 2 2 2 0 Alphavirus glycoprotein J zf-C3HC4 PF00097.25 CBZ31952.1 - 1.7e-09 37.4 8.3 3.6e-09 36.4 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ31952.1 - 5.2e-09 36.0 3.6 5.2e-09 36.0 3.6 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ31952.1 - 7e-09 35.4 11.3 1.2e-08 34.7 3.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ31952.1 - 5.7e-08 32.8 7.4 1.5e-07 31.5 7.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CBZ31952.1 - 5.9e-08 32.5 7.1 1.4e-07 31.3 7.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBZ31952.1 - 3.6e-07 30.0 7.5 6.9e-07 29.0 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ31952.1 - 2.1e-06 27.9 8.5 4.5e-06 26.9 8.5 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ31952.1 - 0.00069 19.4 6.0 0.0015 18.3 6.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CBZ31952.1 - 0.0017 18.6 6.4 0.0053 17.0 6.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Croc_4 PF17691.1 CBZ31952.1 - 0.0049 16.9 0.8 0.013 15.6 0.8 1.7 1 0 0 1 1 1 1 Contingent replication of cDNA 4 U-box PF04564.15 CBZ31952.1 - 0.042 14.0 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 U-box domain zf-ANAPC11 PF12861.7 CBZ31952.1 - 0.047 13.7 2.7 0.1 12.6 2.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 CBZ31952.1 - 0.31 10.9 6.1 0.63 9.9 6.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 CBZ31952.1 - 1.6 8.5 5.7 5.3 6.9 5.7 2.0 1 1 0 1 1 1 0 RING-like zinc finger Kinesin_assoc PF16183.5 CBZ31953.1 - 0.039 14.1 1.0 0.09 12.9 0.6 1.8 1 1 1 2 2 2 0 Kinesin-associated DUF3703 PF12487.8 CBZ31953.1 - 0.059 13.2 0.4 0.19 11.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3703) DUF3138 PF11336.8 CBZ31953.1 - 0.39 9.3 2.7 0.77 8.3 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ALIX_LYPXL_bnd PF13949.6 CBZ31953.1 - 0.65 9.2 6.3 1.2 8.4 6.3 1.3 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV KduI PF04962.12 CBZ31954.1 - 0.0096 15.3 0.1 0.01 15.1 0.1 1.1 1 0 0 1 1 1 1 KduI/IolB family Glyco_hydr_116N PF12215.8 CBZ31954.1 - 0.024 14.1 0.5 0.025 14.0 0.5 1.0 1 0 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term Amidinotransf PF02274.17 CBZ31956.1 - 7.8e-12 44.9 0.0 6e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 Amidinotransferase Pkinase PF00069.25 CBZ31957.1 - 1.1e-47 162.6 0.0 7e-47 160.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31957.1 - 1.5e-33 116.2 0.0 2.9e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ31957.1 - 2.5e-05 23.8 0.0 4.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CBZ31957.1 - 0.0022 17.7 0.0 0.0056 16.3 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CBZ31957.1 - 0.0041 16.0 0.0 0.0065 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ31957.1 - 0.041 13.8 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Tubulin PF00091.25 CBZ31958.1 - 1.3e-45 156.1 0.1 1.4e-45 155.9 0.1 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 CBZ31958.1 - 7.3e-06 26.3 0.0 9.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Hist_deacetyl PF00850.19 CBZ31959.1 - 2.3e-76 257.2 0.2 1.1e-45 156.4 0.2 2.1 2 0 0 2 2 2 2 Histone deacetylase domain SR-25 PF10500.9 CBZ31959.1 - 3.9 7.0 6.8 6.5 6.3 6.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ANAPC4_WD40 PF12894.7 CBZ31961.1 - 0.00014 22.1 0.0 1.1 9.6 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBZ31961.1 - 0.054 12.8 0.0 9.6 5.4 0.0 2.5 2 1 0 2 2 2 0 WD40-like domain WD40 PF00400.32 CBZ31961.1 - 1.6 9.7 5.4 97 4.1 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat PEX11 PF05648.14 CBZ31964.1 - 2.4e-10 40.3 5.0 6.8e-08 32.2 5.0 2.3 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PIG-L PF02585.17 CBZ31965.1 - 1.3e-22 80.8 0.0 1.7e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase HhH-GPD PF00730.25 CBZ31966.1 - 1.4e-20 73.8 0.0 2.1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CBZ31966.1 - 9.2e-07 28.4 0.0 2.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 CBZ31966.1 - 7.4e-05 23.0 4.0 0.00014 22.1 4.0 1.5 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 CBZ31966.1 - 0.026 15.1 0.1 1.9 9.1 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain Toxin_R_bind_C PF07951.12 CBZ31966.1 - 0.089 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Clostridium neurotoxin, C-terminal receptor binding CRS1_YhbY PF01985.21 CBZ31966.1 - 0.14 12.3 0.2 0.14 12.3 0.2 1.6 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain RRM_1 PF00076.22 CBZ31967.1 - 2e-20 72.4 0.0 2.5e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ31967.1 - 0.00018 21.5 0.1 0.0014 18.7 0.0 2.4 1 1 0 2 2 2 1 RNA recognition motif RNA_bind PF08675.11 CBZ31967.1 - 0.0073 16.3 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 RNA binding domain HA2 PF04408.23 CBZ31968.1 - 3.2e-18 66.0 0.0 1.5e-17 63.8 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBZ31968.1 - 9.6e-14 51.5 0.0 2.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBZ31968.1 - 9.6e-13 48.5 0.0 2.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ31968.1 - 2.2e-10 40.6 0.6 4.6e-10 39.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 CBZ31968.1 - 9.6e-05 22.3 1.9 9.6e-05 22.3 1.9 2.7 2 0 0 2 2 2 1 Zinc knuckle T2SSE PF00437.20 CBZ31968.1 - 0.00014 21.0 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CBZ31968.1 - 0.00042 20.7 0.1 0.0017 18.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain RWD PF05773.22 CBZ31968.1 - 0.00045 20.5 0.0 0.0017 18.6 0.0 2.0 2 0 0 2 2 2 1 RWD domain AAA_22 PF13401.6 CBZ31968.1 - 0.0058 16.9 3.7 0.015 15.6 0.5 3.2 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.6 CBZ31968.1 - 0.032 14.0 0.1 0.096 12.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CBZ31968.1 - 0.14 11.5 0.0 0.34 10.2 0.0 1.6 1 0 0 1 1 1 0 KaiC SRP54 PF00448.22 CBZ31968.1 - 0.17 11.5 0.6 4.5 6.9 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RRM_1 PF00076.22 CBZ31969.1 - 5.8e-19 67.7 0.0 9.4e-19 67.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ31969.1 - 0.0014 18.7 0.1 0.0041 17.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 CBZ31969.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBZ31970.1 - 4.4e-16 58.4 0.0 7.1e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ifi-6-16 PF06140.13 CBZ31970.1 - 0.023 14.6 0.2 0.023 14.6 0.2 2.3 3 0 0 3 3 3 0 Interferon-induced 6-16 family BILBO1_N PF18281.1 CBZ31971.1 - 1.7e-31 108.5 0.1 6.1e-31 106.7 0.1 2.0 1 0 0 1 1 1 1 BILBO1 N-terminal domain EF-hand_7 PF13499.6 CBZ31971.1 - 1.7e-10 41.2 3.3 1.7e-10 41.2 3.3 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ31971.1 - 5.1e-07 28.8 4.1 0.0052 16.2 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBZ31971.1 - 6.6e-06 25.6 2.9 0.073 13.0 0.5 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBZ31971.1 - 7.1e-05 22.6 1.6 0.0023 17.8 0.7 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ31971.1 - 0.0059 16.0 0.0 0.019 14.4 0.0 1.9 1 0 0 1 1 1 1 EF hand SPARC_Ca_bdg PF10591.9 CBZ31971.1 - 2 8.7 0.0 2 8.7 0.0 3.5 3 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3584 PF12128.8 CBZ31971.1 - 3.5 5.0 65.2 0.12 9.9 31.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 CBZ31971.1 - 8.6 6.5 23.8 9.4 6.4 4.1 3.3 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Phycobilisome PF00502.19 CBZ31972.1 - 0.041 13.8 1.1 0.072 13.0 0.5 1.7 2 0 0 2 2 2 0 Phycobilisome protein Kinesin PF00225.23 CBZ31974.1 - 4e-75 252.8 0.0 6.5e-44 150.2 0.0 2.7 2 1 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ31974.1 - 7.4e-17 61.7 0.1 2.9e-16 59.8 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 CBZ31974.1 - 0.078 13.2 3.2 0.13 12.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CBZ31974.1 - 0.12 12.5 0.0 0.12 12.5 0.0 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain zf-CRD PF17979.1 CBZ31975.1 - 2e-43 148.3 1.2 2e-43 148.3 1.2 2.4 2 0 0 2 2 2 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 CBZ31975.1 - 1e-14 54.6 0.1 2e-14 53.7 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-CCHH PF10283.9 CBZ31975.1 - 3.5e-09 36.5 10.2 8.9e-09 35.2 10.2 1.8 1 0 0 1 1 1 1 PBZ domain zf-C3HC4 PF00097.25 CBZ31975.1 - 1e-06 28.5 11.9 1e-06 28.5 11.9 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ31975.1 - 3.8e-06 26.6 13.5 3.8e-06 26.6 13.5 3.4 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ31975.1 - 6.6e-06 26.4 13.1 6.6e-06 26.4 13.1 3.5 3 0 0 3 3 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBZ31975.1 - 3e-05 23.9 12.1 3e-05 23.9 12.1 3.1 4 0 0 4 4 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ31975.1 - 4.9e-05 23.2 11.9 4.9e-05 23.2 11.9 3.5 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBZ31975.1 - 6.8e-05 22.9 12.2 6.8e-05 22.9 12.2 3.4 3 1 1 4 4 3 1 zinc finger of C3HC4-type, RING FHA_2 PF17913.1 CBZ31975.1 - 0.00013 22.1 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 FHA domain zf-RING_6 PF14835.6 CBZ31975.1 - 0.00019 21.2 6.6 0.00019 21.2 6.6 2.9 2 1 0 2 2 2 1 zf-RING of BARD1-type protein Yop-YscD_cpl PF16697.5 CBZ31975.1 - 0.0023 18.2 0.2 0.0044 17.3 0.2 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-Nse PF11789.8 CBZ31975.1 - 0.14 12.0 5.0 0.39 10.6 5.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Atg8 PF02991.16 CBZ31976.1 - 7.5e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Atg8 PF02991.16 CBZ31977.1 - 9.7e-06 25.7 0.0 1.7e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Atg8 PF02991.16 CBZ31979.1 - 7.1e-06 26.2 0.0 1.3e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like TANGO2 PF05742.12 CBZ31981.1 - 3.3e-17 63.4 0.0 1.7e-13 51.2 0.0 3.2 2 1 0 2 2 2 2 Transport and Golgi organisation 2 DUF4586 PF15239.6 CBZ31982.1 - 7.2e-35 121.6 6.2 1e-34 121.1 6.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Kinesin PF00225.23 CBZ31984.1 - 2.6e-30 105.5 0.6 1e-10 41.1 0.0 3.9 4 0 0 4 4 4 3 Kinesin motor domain DUF2380 PF09533.10 CBZ31984.1 - 0.12 12.0 1.9 0.35 10.5 1.9 1.8 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Microtub_bd PF16796.5 CBZ31984.1 - 0.24 11.3 0.2 0.85 9.6 0.0 1.9 2 0 0 2 2 2 0 Microtubule binding Tmemb_cc2 PF10267.9 CBZ31984.1 - 0.35 9.9 0.7 0.81 8.8 0.0 1.9 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein DUF4123 PF13503.6 CBZ31985.1 - 0.049 14.1 0.9 0.1 13.0 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4123) DUF1180 PF06679.12 CBZ31985.1 - 9.1 6.7 8.2 17 5.8 8.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Pkinase PF00069.25 CBZ31986.1 - 1.5e-49 168.7 0.0 1.4e-48 165.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31986.1 - 1e-20 74.1 0.1 2e-19 69.9 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ31986.1 - 9.5e-05 21.8 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ31986.1 - 0.00012 22.1 0.0 0.00012 22.1 0.0 2.4 2 2 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ31986.1 - 0.0051 16.2 0.1 0.011 15.1 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ31986.1 - 0.0089 15.0 0.0 0.016 14.2 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBZ31986.1 - 0.017 13.9 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 CBZ31986.1 - 0.053 13.1 0.0 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family CHASE PF03924.13 CBZ31987.1 - 0.0044 17.0 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 CHASE domain DUF2833 PF11090.8 CBZ31987.1 - 0.2 12.1 0.0 0.42 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) DUF3040 PF11239.8 CBZ31988.1 - 0.097 12.9 3.3 1.5 9.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF2833 PF11090.8 CBZ31988.1 - 0.18 12.2 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) Rap1_C PF11626.8 CBZ31990.1 - 0.017 15.2 0.1 0.099 12.7 0.0 2.2 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-RING_2 PF13639.6 CBZ31991.1 - 2e-08 34.4 7.2 2e-08 34.4 7.2 2.7 3 0 0 3 3 2 1 Ring finger domain zf-rbx1 PF12678.7 CBZ31991.1 - 2.3e-08 34.2 1.9 2.3e-08 34.2 1.9 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBZ31991.1 - 9.1e-05 22.1 4.9 0.00031 20.4 1.1 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBZ31991.1 - 0.0001 22.1 8.9 0.0001 22.1 8.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ31991.1 - 0.00042 20.1 3.0 0.00042 20.1 3.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBZ31991.1 - 0.00046 20.2 1.6 0.0012 18.9 1.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CBZ31991.1 - 0.0013 18.5 6.3 0.0013 18.5 6.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ31991.1 - 0.0051 16.6 5.0 0.014 15.2 5.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBZ31991.1 - 0.0059 16.6 3.6 0.0059 16.6 3.6 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ31991.1 - 0.073 13.0 9.5 0.02 14.8 5.9 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CBZ31991.1 - 0.92 9.2 9.3 0.14 11.8 4.9 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 CBZ31991.1 - 1.7 8.9 9.5 0.4 10.9 5.4 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 CBZ31991.1 - 3.2 7.9 6.6 7.2 6.7 6.6 1.6 1 0 0 1 1 1 0 Zinc-finger FAD_binding_7 PF03441.14 CBZ31992.1 - 2e-34 118.9 0.3 3.2e-34 118.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CBZ31992.1 - 1.4e-19 70.7 0.4 7.2e-19 68.4 0.2 2.3 2 0 0 2 2 2 1 DNA photolyase Ank_4 PF13637.6 CBZ31993.1 - 1.5e-07 31.8 0.1 6.2e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ31993.1 - 7.5e-05 23.2 0.0 0.00017 22.1 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ31993.1 - 0.00023 21.3 0.5 0.0051 17.2 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CBZ31993.1 - 0.012 15.9 0.1 0.061 13.7 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 CBZ31993.1 - 0.13 12.8 0.2 0.65 10.6 0.0 2.2 3 0 0 3 3 3 0 Ankyrin repeat CX9C PF16860.5 CBZ31994.1 - 4.8e-07 29.7 1.0 8.7e-07 28.8 1.0 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 CBZ31994.1 - 0.015 15.5 1.3 0.67 10.2 1.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) GCK PF07802.11 CBZ31994.1 - 0.026 14.9 0.2 0.039 14.4 0.2 1.3 1 0 0 1 1 1 0 GCK domain Cmc1 PF08583.10 CBZ31994.1 - 0.075 13.1 1.8 0.18 11.8 1.5 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CBZ31994.1 - 0.27 11.4 4.2 6 7.1 0.2 2.6 3 0 0 3 3 3 0 CHCH domain NDUF_B7 PF05676.13 CBZ31994.1 - 1.4 8.7 6.2 3.8 7.3 0.6 2.7 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DUF2844 PF11005.8 CBZ31996.1 - 0.059 13.4 2.2 0.34 10.9 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2844) FAM76 PF16046.5 CBZ31996.1 - 0.45 9.8 7.2 1 8.6 7.3 1.7 1 1 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 CBZ31996.1 - 1.5 7.6 12.4 2.4 6.9 12.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 CBZ31996.1 - 2.8 7.1 5.1 4.5 6.4 5.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF3150 PF11348.8 CBZ31997.1 - 0.0051 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3150) Pkinase PF00069.25 CBZ31998.1 - 6.8e-05 22.4 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ31998.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase VTC PF09359.10 CBZ31999.1 - 4.4e-77 259.2 0.1 6.8e-77 258.6 0.1 1.3 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 CBZ31999.1 - 1.4e-05 25.4 0.6 1.4e-05 25.4 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4199 PF13858.6 CBZ31999.1 - 0.21 12.0 0.3 0.39 11.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) AAA_2 PF07724.14 CBZ32000.1 - 9.3e-42 143.0 0.2 1.7e-33 116.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CBZ32000.1 - 1.3e-12 48.3 0.5 8.9e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CBZ32000.1 - 1.9e-06 27.8 0.2 9.8e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CBZ32000.1 - 4.1e-06 26.8 0.1 8.1e-05 22.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 CBZ32000.1 - 9e-05 21.7 0.1 0.012 14.7 0.0 2.4 2 0 0 2 2 2 1 MCM P-loop domain AAA_22 PF13401.6 CBZ32000.1 - 0.00015 22.0 0.1 0.0031 17.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ32000.1 - 0.0009 19.7 4.2 0.031 14.7 3.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.25 CBZ32000.1 - 0.0057 16.3 0.1 0.01 15.5 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 CBZ32000.1 - 0.012 16.2 0.0 0.17 12.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBZ32000.1 - 0.013 14.8 0.7 0.056 12.8 0.0 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CBZ32000.1 - 0.016 14.9 0.0 0.18 11.5 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.12 CBZ32000.1 - 0.021 14.6 0.0 0.64 9.7 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 CBZ32000.1 - 0.033 14.5 0.3 0.11 12.8 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ32000.1 - 0.04 13.4 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region DEAD PF00270.29 CBZ32000.1 - 0.055 13.2 0.1 11 5.8 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_24 PF13479.6 CBZ32000.1 - 0.065 13.0 0.1 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CBZ32000.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein AAA_28 PF13521.6 CBZ32000.1 - 0.089 13.0 0.4 0.58 10.4 0.2 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBZ32000.1 - 0.093 13.2 0.0 0.66 10.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.6 CBZ32000.1 - 0.095 12.9 0.2 0.49 10.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_8 PF12780.7 CBZ32000.1 - 0.12 11.7 0.0 0.46 9.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 UCH PF00443.29 CBZ32001.1 - 1.9e-37 129.2 0.0 2.9e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ32001.1 - 6.9e-05 22.6 0.2 0.00046 19.9 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MCM PF00493.23 CBZ32002.1 - 6.2e-90 300.2 0.0 3.4e-89 297.8 0.0 2.0 1 1 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ32002.1 - 2.6e-35 121.0 0.6 5e-35 120.1 0.6 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ32002.1 - 1.3e-23 83.2 2.2 2.5e-23 82.3 2.2 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBZ32002.1 - 4.2e-10 40.1 0.0 1.4e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 CBZ32002.1 - 4.9e-09 36.3 0.0 1.1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBZ32002.1 - 4.4e-08 32.8 0.3 1.2e-05 24.8 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CBZ32002.1 - 0.0012 18.5 0.0 0.055 13.2 0.0 2.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 CBZ32002.1 - 0.0017 18.8 0.2 0.036 14.4 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 CBZ32002.1 - 0.0021 17.9 0.0 0.0052 16.6 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CBZ32002.1 - 0.083 12.8 0.1 18 5.2 0.0 2.5 1 1 1 2 2 2 0 NTPase Med31 PF05669.12 CBZ32002.1 - 0.093 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 SOH1 G10 PF01125.17 CBZ32003.1 - 1.1e-47 161.5 0.3 3.3e-47 159.9 0.3 1.7 1 1 0 1 1 1 1 G10 protein MFS_1 PF07690.16 CBZ32004.1 - 2.2e-20 72.9 37.4 1.3e-15 57.2 13.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBZ32004.1 - 0.0013 17.6 5.8 0.0013 17.6 5.8 1.7 2 0 0 2 2 2 1 MFS_1 like family Pkinase PF00069.25 CBZ32006.1 - 7.3e-05 22.3 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32006.1 - 0.018 14.4 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DSPn PF14671.6 CBZ32007.1 - 1.6e-18 67.5 0.0 1.1e-11 45.3 0.0 2.4 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CBZ32007.1 - 3.9e-08 33.2 0.1 7.3e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ32007.1 - 0.00093 18.8 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Plus-3 PF03126.18 CBZ32008.1 - 9.2e-15 55.1 0.0 3.1e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain zf-C3HC4_3 PF13920.6 CBZ32008.1 - 2e-09 37.1 15.0 3.1e-09 36.5 15.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ32008.1 - 0.016 15.0 14.1 0.029 14.2 14.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TPR_1 PF00515.28 CBZ32009.1 - 8.9e-16 57.0 15.0 0.0031 17.3 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ32009.1 - 1.3e-14 53.1 14.1 0.075 13.2 0.0 9.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ32009.1 - 2.2e-13 49.2 3.8 0.085 13.1 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ32009.1 - 5.3e-12 45.5 12.0 0.1 13.5 0.2 7.4 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ32009.1 - 8.5e-09 35.9 12.0 0.57 10.9 0.0 6.9 5 1 3 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ32009.1 - 2.6e-08 34.0 16.9 0.023 15.0 0.0 6.8 5 1 3 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ32009.1 - 3.5e-08 33.5 5.6 0.0086 16.2 0.3 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ32009.1 - 2e-07 31.4 9.6 0.042 14.4 0.2 5.5 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ32009.1 - 0.00022 21.4 0.9 18 6.0 0.0 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ32009.1 - 0.00058 20.3 4.1 6.7 7.6 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ32009.1 - 0.012 15.3 8.2 14 5.5 0.1 5.9 5 2 1 6 6 6 0 TPR repeat Fis1_TPR_C PF14853.6 CBZ32009.1 - 0.04 14.0 9.4 0.23 11.6 0.0 4.7 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 CBZ32009.1 - 0.16 12.0 6.8 70 3.8 0.2 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ32009.1 - 0.95 9.7 11.8 14 6.0 0.1 5.2 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CBZ32009.1 - 5.5 7.0 13.0 52 3.9 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4094 PF13334.6 CBZ32010.1 - 0.022 15.2 3.7 2.6 8.5 0.8 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) KxDL PF10241.9 CBZ32010.1 - 1.1 9.6 11.9 7.4 6.9 0.1 4.6 4 0 0 4 4 4 0 Uncharacterized conserved protein Mon2_C PF16206.5 CBZ32011.1 - 2.4e-09 35.9 0.1 4.3e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 CBZ32011.1 - 0.13 12.2 0.1 25 4.8 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Metallophos PF00149.28 CBZ32012.1 - 1.3e-21 78.1 0.7 1.9e-21 77.5 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Herpes_BLRF2 PF05812.12 CBZ32012.1 - 0.2 11.8 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein IRK_C PF17655.1 CBZ32013.1 - 7e-07 29.0 0.1 0.0016 18.0 0.0 2.8 3 0 0 3 3 3 2 Inward rectifier potassium channel C-terminal domain Acyltransferase PF01553.21 CBZ32014.1 - 0.1 12.2 0.0 18 5.0 0.0 2.3 2 0 0 2 2 2 0 Acyltransferase LRR_4 PF12799.7 CBZ32018.1 - 0.002 18.5 9.1 4.7 7.8 0.0 5.8 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ32018.1 - 0.018 14.8 4.7 1.7 8.4 0.0 4.7 5 1 0 5 5 5 0 Leucine rich repeat Med9 PF07544.13 CBZ32018.1 - 0.16 12.1 1.7 0.36 10.9 1.7 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 LRR_9 PF14580.6 CBZ32018.1 - 0.17 11.4 0.0 0.52 9.8 0.0 1.8 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 CBZ32018.1 - 0.34 11.1 5.2 4.4 7.6 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ32018.1 - 7.3 7.6 5.4 89 4.3 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat DSPc PF00782.20 CBZ32020.1 - 8.9e-09 35.3 0.3 6.8e-07 29.2 0.2 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain His_Phos_1 PF00300.22 CBZ32021.1 - 9.4e-12 45.0 0.0 3.5e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CBZ32021.1 - 0.027 13.8 0.0 0.054 12.8 0.0 1.4 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Pribosyltran PF00156.27 CBZ32021.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Yippee-Mis18 PF03226.14 CBZ32022.1 - 0.028 14.6 0.7 1.1 9.4 0.4 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LRR_8 PF13855.6 CBZ32023.1 - 8.6e-06 25.4 0.9 0.011 15.5 0.2 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBZ32023.1 - 0.0018 18.7 4.8 0.5 10.9 0.5 3.5 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CBZ32023.1 - 0.16 12.3 3.8 0.18 12.1 0.5 2.6 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain UvrD-helicase PF00580.21 CBZ32024.1 - 1.5e-38 133.1 0.0 8.8e-36 124.0 0.0 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CBZ32024.1 - 2.3e-27 96.3 0.0 5.7e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CBZ32024.1 - 2.7e-25 89.4 0.0 8.3e-25 87.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CBZ32024.1 - 2.4e-09 36.9 0.1 7.9e-09 35.2 0.1 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 CBZ32024.1 - 9.4e-09 35.3 1.3 8.2e-05 22.4 0.2 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 CBZ32024.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Prenyltransf PF01255.19 CBZ32024.1 - 0.14 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Peptidase_S51 PF03575.17 CBZ32025.1 - 1.1e-24 87.2 0.0 7.5e-23 81.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase family S51 PRKCSH-like PF12999.7 CBZ32026.1 - 4e-08 33.3 0.0 5.2e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like DUF913 PF06025.12 CBZ32027.1 - 0.0019 17.3 1.0 0.071 12.1 0.0 2.6 3 0 0 3 3 3 2 Domain of Unknown Function (DUF913) DUF4140 PF13600.6 CBZ32027.1 - 3.4 8.2 10.3 4.6 7.8 4.0 3.6 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) SUIM_assoc PF16619.5 CBZ32027.1 - 4.9 7.3 21.9 0.076 13.1 1.9 3.6 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 G0-G1_switch_2 PF15103.6 CBZ32027.1 - 6.9 7.2 6.1 6.6 7.2 0.1 3.2 3 0 0 3 3 3 0 G0/G1 switch protein 2 PH PF00169.29 CBZ32028.1 - 3e-10 40.5 0.0 5.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 CBZ32028.1 - 0.0084 15.9 0.1 0.73 9.6 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_5 PF15405.6 CBZ32028.1 - 0.15 12.2 0.2 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain TetR_C_31 PF17940.1 CBZ32028.1 - 5.1 7.4 8.9 11 6.3 0.5 3.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain DHHC PF01529.20 CBZ32029.1 - 3.2e-26 92.0 12.7 3.2e-26 92.0 12.7 3.0 2 1 1 3 3 3 2 DHHC palmitoyltransferase AAA_33 PF13671.6 CBZ32030.1 - 3.1e-06 27.4 0.2 2.9e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CBZ32030.1 - 5.6e-06 25.8 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 CBZ32030.1 - 0.00096 19.7 0.1 0.0051 17.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CBZ32030.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.6 CBZ32030.1 - 0.0021 18.4 0.1 0.0076 16.6 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 CBZ32030.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase PRK PF00485.18 CBZ32030.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 CBZ32030.1 - 0.11 12.8 0.0 0.4 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CBZ32030.1 - 0.15 12.3 0.0 0.79 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBZ32030.1 - 0.16 12.5 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TYW3 PF02676.14 CBZ32031.1 - 3.9e-58 196.3 0.0 4.8e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Itfg2 PF15907.5 CBZ32031.1 - 0.17 10.9 0.2 0.6 9.1 0.0 1.8 1 1 1 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 Prefoldin_2 PF01920.20 CBZ32032.1 - 1.8e-18 66.5 1.6 2.2e-18 66.1 1.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.12 CBZ32032.1 - 0.018 15.6 2.2 0.36 11.5 0.0 2.3 2 0 0 2 2 2 0 SlyX DASH_Dad3 PF08656.10 CBZ32032.1 - 0.027 14.5 0.7 0.027 14.5 0.7 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 GreA_GreB_N PF03449.15 CBZ32032.1 - 0.065 13.4 1.9 0.096 12.9 0.4 1.9 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal zf-CpG_bind_C PF12269.8 CBZ32032.1 - 0.26 11.0 2.6 1.1 9.0 0.5 2.0 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Spc24 PF08286.11 CBZ32032.1 - 0.88 9.8 5.0 3.1 8.1 0.6 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 zf_CCCH_4 PF18345.1 CBZ32037.1 - 2.2e-18 65.7 28.9 5.4e-07 29.5 1.6 6.1 5 1 0 5 5 5 5 Zinc finger domain zf-CCCH PF00642.24 CBZ32037.1 - 9.9e-18 63.6 30.3 0.00055 19.8 0.6 5.5 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ32037.1 - 1.6e-11 43.7 26.7 4.4e-07 29.5 0.6 5.0 5 0 0 5 5 5 4 CCCH-type zinc finger Torus PF16131.5 CBZ32037.1 - 1.8e-11 44.7 21.0 0.0007 20.3 0.4 5.2 1 1 4 5 5 5 5 Torus domain zf-CCCH_3 PF15663.5 CBZ32037.1 - 1.8e-07 31.3 7.0 1.8e-07 31.3 7.0 2.6 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCHC PF00098.23 CBZ32037.1 - 0.00011 22.1 11.4 0.00035 20.5 0.5 3.4 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_2 PF13696.6 CBZ32037.1 - 0.00017 21.3 4.4 0.0016 18.2 0.4 3.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCCH_2 PF14608.6 CBZ32037.1 - 0.00048 20.5 1.1 0.00048 20.5 1.1 6.7 7 0 0 7 7 7 3 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 CBZ32037.1 - 2.6 7.9 8.9 0.82 9.5 0.1 4.0 3 0 0 3 3 3 0 Putative zinc-finger domain zf-UBR PF02207.20 CBZ32039.1 - 1.2e-15 57.4 14.7 1.2e-15 57.4 14.7 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Rrn6 PF10214.9 CBZ32039.1 - 0.16 10.4 0.3 0.31 9.5 0.3 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Rtf2 PF04641.12 CBZ32039.1 - 2.2 7.5 9.8 2.2 7.6 0.7 2.5 2 0 0 2 2 2 0 Rtf2 RING-finger ACBP PF00887.19 CBZ32040.1 - 1.2e-23 83.1 0.6 2.6e-23 82.0 0.6 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein DUF4486 PF14858.6 CBZ32041.1 - 0.0089 14.6 0.0 0.017 13.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4486) HA PF03457.14 CBZ32041.1 - 0.098 13.0 0.6 1.4 9.3 0.0 3.0 3 0 0 3 3 3 0 Helicase associated domain Type_III_YscG PF09477.10 CBZ32041.1 - 0.77 9.9 4.0 15 5.7 0.0 4.2 4 0 0 4 4 4 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Peptidase_S9_N PF02897.15 CBZ32042.1 - 2.3e-118 395.6 0.2 3.3e-118 395.1 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CBZ32042.1 - 6.1e-66 221.9 0.0 9.8e-66 221.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4464 PF14713.6 CBZ32043.1 - 2.1e-84 282.6 0.2 2.5e-84 282.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) RNase_P_p30 PF01876.16 CBZ32044.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 RNase P subunit p30 GAS PF13851.6 CBZ32044.1 - 0.22 10.9 0.3 0.36 10.1 0.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Latarcin PF10279.9 CBZ32045.1 - 0.18 12.2 11.5 0.45 10.9 0.0 4.9 3 2 0 3 3 3 0 Latarcin precursor ABC_membrane PF00664.23 CBZ32045.1 - 0.3 10.7 0.5 0.62 9.7 0.5 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region Prefoldin PF02996.17 CBZ32046.1 - 3.5e-08 33.4 0.1 2.2e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Prefoldin subunit AAA PF00004.29 CBZ32047.1 - 0.00014 22.3 0.0 0.00031 21.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CBZ32047.1 - 0.013 14.8 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 CBZ32047.1 - 0.019 15.4 0.2 0.13 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain LrgB PF04172.16 CBZ32047.1 - 0.12 11.8 0.8 0.22 11.0 0.8 1.4 1 0 0 1 1 1 0 LrgB-like family DEAD PF00270.29 CBZ32048.1 - 4.1e-26 91.8 0.1 6.4e-26 91.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ32048.1 - 3.1e-20 72.6 0.1 2e-19 70.0 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ32048.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBZ32048.1 - 0.044 14.1 0.0 0.09 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain T3SS_needle_reg PF09025.10 CBZ32048.1 - 0.12 12.3 0.2 15 5.5 0.1 2.5 2 0 0 2 2 2 0 YopR, type III needle-polymerisation regulator AAA_11 PF13086.6 CBZ32048.1 - 0.13 12.1 0.1 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain UPF0160 PF03690.13 CBZ32049.1 - 5.1e-121 404.2 0.0 5.9e-121 404.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ras PF00071.22 CBZ32050.1 - 1.9e-34 118.6 0.0 1.9e-11 43.8 0.1 3.0 3 0 0 3 3 3 3 Ras family Roc PF08477.13 CBZ32050.1 - 6.9e-20 71.5 0.2 1.1e-09 38.6 0.0 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ32050.1 - 0.00018 21.0 0.0 0.87 9.0 0.0 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family PET117 PF15786.5 CBZ32051.1 - 0.00043 20.5 0.0 0.0005 20.3 0.0 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial GvpL_GvpF PF06386.11 CBZ32052.1 - 0.85 9.5 13.1 1.6 8.6 13.1 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PhoLip_ATPase_C PF16212.5 CBZ32054.1 - 4.9e-52 177.2 16.3 4.9e-52 177.2 16.3 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBZ32054.1 - 4.3e-20 71.2 0.2 1.1e-19 69.8 0.2 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CBZ32054.1 - 3.1e-09 37.4 0.2 0.00077 19.8 0.0 3.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CBZ32054.1 - 0.0011 18.5 0.0 0.0057 16.2 0.0 2.2 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBZ32054.1 - 0.0086 16.1 0.0 0.16 12.1 0.0 2.8 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CBZ32054.1 - 0.014 15.1 0.1 0.03 14.1 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1635 PF07795.11 CBZ32054.1 - 6.5 6.5 6.0 1.2 8.9 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) EF-hand_6 PF13405.6 CBZ32055.1 - 2.4e-06 27.0 0.6 2e-05 24.2 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 CBZ32055.1 - 7.8e-06 26.2 0.6 8.2e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ32055.1 - 1.5e-05 24.2 3.4 0.00012 21.3 0.0 3.0 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 CBZ32055.1 - 0.00049 19.9 1.7 0.043 13.7 0.5 2.7 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 CBZ32055.1 - 0.067 13.5 0.1 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_14 PF17959.1 CBZ32055.1 - 0.14 12.5 0.9 4.5 7.7 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain YokU PF14122.6 CBZ32055.1 - 2.5 8.1 5.9 2.8 8.0 0.9 2.7 1 1 2 3 3 3 0 YokU-like protein, putative antitoxin EF-hand_5 PF13202.6 CBZ32055.1 - 3.4 7.3 0.0 3.4 7.3 0.0 3.2 3 0 0 3 3 3 0 EF hand EF-hand_1 PF00036.32 CBZ32056.1 - 3e-43 142.2 12.0 1.5e-10 39.9 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBZ32056.1 - 1.6e-36 124.6 3.7 6.9e-19 68.1 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBZ32056.1 - 5e-32 109.5 11.3 1.3e-14 53.7 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBZ32056.1 - 2.1e-31 105.1 6.6 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBZ32056.1 - 3.2e-28 95.9 9.4 5.8e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CBZ32056.1 - 6.6e-16 58.4 0.2 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBZ32056.1 - 1.3e-09 37.9 0.8 5.4e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBZ32056.1 - 6.6e-08 32.9 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBZ32056.1 - 2.6e-06 28.2 0.0 0.00063 20.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CBZ32056.1 - 1.9e-05 24.6 1.0 0.035 14.1 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CBZ32056.1 - 0.00016 21.7 1.1 0.00074 19.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CBZ32056.1 - 0.00017 21.7 2.8 0.017 15.3 0.4 3.1 1 1 2 3 3 3 1 Dockerin type I domain TerB PF05099.13 CBZ32056.1 - 0.00041 20.3 0.3 0.23 11.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 CBZ32056.1 - 0.00091 20.0 0.3 3.2 8.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CBZ32056.1 - 0.0013 18.6 0.8 0.21 11.5 0.3 3.3 1 1 1 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CBZ32056.1 - 0.0018 18.6 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 CBZ32056.1 - 0.0024 18.3 0.0 0.92 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 CBZ32056.1 - 0.0042 17.3 0.2 0.9 9.8 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 CBZ32056.1 - 0.0059 16.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain DUF1103 PF06513.11 CBZ32056.1 - 0.0061 16.2 1.1 0.0071 16.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 CBZ32056.1 - 0.015 15.2 1.4 0.56 10.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 CBZ32056.1 - 0.019 13.6 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 CBZ32056.1 - 0.033 14.5 0.2 5.6 7.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain dCache_2 PF08269.11 CBZ32056.1 - 0.04 13.1 0.1 2.7 7.1 0.0 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 CBZ32056.1 - 0.045 13.4 0.2 0.11 12.1 0.2 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.6 CBZ32056.1 - 0.081 13.1 0.9 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein EF-hand_1 PF00036.32 CBZ32057.1 - 3e-43 142.2 12.0 1.5e-10 39.9 1.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBZ32057.1 - 1.6e-36 124.6 3.7 6.9e-19 68.1 1.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CBZ32057.1 - 5e-32 109.5 11.3 1.3e-14 53.7 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CBZ32057.1 - 2.1e-31 105.1 6.6 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CBZ32057.1 - 3.2e-28 95.9 9.4 5.8e-07 28.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CBZ32057.1 - 6.6e-16 58.4 0.2 6.8e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBZ32057.1 - 1.3e-09 37.9 0.8 5.4e-05 23.1 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBZ32057.1 - 6.6e-08 32.9 0.0 0.0014 18.9 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CBZ32057.1 - 2.6e-06 28.2 0.0 0.00063 20.6 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 CBZ32057.1 - 1.9e-05 24.6 1.0 0.035 14.1 0.0 3.3 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CBZ32057.1 - 0.00016 21.7 1.1 0.00074 19.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 CBZ32057.1 - 0.00017 21.7 2.8 0.017 15.3 0.4 3.1 1 1 2 3 3 3 1 Dockerin type I domain TerB PF05099.13 CBZ32057.1 - 0.00041 20.3 0.3 0.23 11.4 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB DUF3349 PF11829.8 CBZ32057.1 - 0.00091 20.0 0.3 3.2 8.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 CBZ32057.1 - 0.0013 18.6 0.8 0.21 11.5 0.3 3.3 1 1 1 2 2 2 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CBZ32057.1 - 0.0018 18.6 0.3 1.6 9.1 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 DUF4497 PF14924.6 CBZ32057.1 - 0.0024 18.3 0.0 0.92 10.0 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) Poly_export PF02563.16 CBZ32057.1 - 0.0042 17.3 0.2 0.9 9.8 0.0 3.1 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein MotA_activ PF09114.10 CBZ32057.1 - 0.0059 16.7 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain DUF1103 PF06513.11 CBZ32057.1 - 0.0061 16.2 1.1 0.0071 16.0 1.1 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) SurA_N_2 PF13623.6 CBZ32057.1 - 0.015 15.2 1.4 0.56 10.1 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF5580 PF17743.1 CBZ32057.1 - 0.019 13.6 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 CBZ32057.1 - 0.033 14.5 0.2 5.6 7.4 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain dCache_2 PF08269.11 CBZ32057.1 - 0.04 13.1 0.1 2.7 7.1 0.0 2.2 1 1 0 2 2 2 0 Cache domain Fe_hyd_lg_C PF02906.14 CBZ32057.1 - 0.045 13.4 0.2 0.11 12.1 0.2 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain RloB PF13707.6 CBZ32057.1 - 0.081 13.1 0.9 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 RloB-like protein FbpA PF05833.11 CBZ32058.1 - 9.7e-31 107.0 8.7 7.9e-22 77.6 0.0 2.7 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 CBZ32058.1 - 5e-23 81.8 0.0 1.5e-22 80.3 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 CBZ32058.1 - 8e-08 32.2 0.0 8e-08 32.2 0.0 3.7 4 0 0 4 4 4 1 NFACT protein C-terminal domain SepSecS PF05889.13 CBZ32059.1 - 1.4e-91 307.1 0.0 1.1e-51 175.8 0.0 3.6 3 1 0 3 3 3 3 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 CBZ32059.1 - 4.4e-06 26.2 0.0 9.8e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase DUF3854 PF12965.7 CBZ32059.1 - 0.047 13.7 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) DUF3783 PF12646.7 CBZ32059.1 - 0.14 12.1 0.0 13 5.9 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3783) DUF2550 PF10739.9 CBZ32060.1 - 0.068 13.2 0.1 0.23 11.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) Reo_sigma1 PF01664.16 CBZ32060.1 - 0.13 11.5 0.2 0.31 10.3 0.2 1.6 1 0 0 1 1 1 0 Reovirus viral attachment protein sigma 1 EF1G PF00647.19 CBZ32061.1 - 3.2e-38 130.1 1.5 6.4e-38 129.1 0.2 2.2 2 1 1 3 3 3 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CBZ32061.1 - 2e-12 47.2 3.2 2.2e-12 47.0 0.1 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBZ32061.1 - 6.1e-12 45.7 0.0 3.2e-11 43.4 0.0 2.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBZ32061.1 - 2.7e-06 27.5 1.5 4.5e-06 26.8 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBZ32061.1 - 4e-05 23.5 0.0 9.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CBZ32061.1 - 0.00012 22.4 0.0 0.00038 20.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 CBZ32061.1 - 0.1 13.0 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain EF1G PF00647.19 CBZ32062.1 - 6.7e-12 45.4 0.1 9.6e-12 44.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain PAM2 PF07145.15 CBZ32063.1 - 0.002 17.7 1.4 0.78 9.6 0.0 3.3 3 0 0 3 3 3 2 Ataxin-2 C-terminal region DUF1674 PF07896.12 CBZ32063.1 - 0.088 13.3 1.5 0.67 10.5 1.5 2.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) Chorein_N PF12624.7 CBZ32064.1 - 1.8e-19 69.9 0.1 4.1e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 PUB PF09409.10 CBZ32065.1 - 2.1e-11 43.6 0.1 4e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 PUB domain NPCBM_assoc PF10633.9 CBZ32066.1 - 0.0094 16.2 1.8 0.06 13.6 0.1 2.6 2 0 0 2 2 2 1 NPCBM-associated, NEW3 domain of alpha-galactosidase CDC50 PF03381.15 CBZ32067.1 - 3.4e-66 223.6 0.1 5.3e-66 223.0 0.1 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Wtap PF17098.5 CBZ32068.1 - 0.00037 20.5 2.7 0.00048 20.1 1.8 1.7 1 1 0 1 1 1 1 WTAP/Mum2p family Takusan PF04822.13 CBZ32068.1 - 0.0007 19.4 6.6 0.0085 16.0 3.4 3.1 2 1 1 3 3 3 1 Takusan DUF3379 PF11859.8 CBZ32068.1 - 0.082 12.2 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) PTS_EIIB PF00367.20 CBZ32068.1 - 0.089 12.3 0.3 0.23 11.0 0.3 1.6 1 0 0 1 1 1 0 phosphotransferase system, EIIB YabA PF06156.13 CBZ32068.1 - 0.19 12.4 2.5 0.24 12.0 0.4 2.2 2 1 1 3 3 3 0 Initiation control protein YabA Cep57_CLD_2 PF14197.6 CBZ32068.1 - 0.3 11.2 15.6 0.11 12.6 4.8 2.8 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 GAS PF13851.6 CBZ32068.1 - 0.39 10.0 8.3 1.7 7.9 2.6 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2508 PF10704.9 CBZ32068.1 - 0.5 10.6 2.9 3.6 7.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) TMF_TATA_bd PF12325.8 CBZ32068.1 - 0.87 9.8 6.6 0.31 11.3 2.4 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 CBZ32068.1 - 1.8 9.5 11.4 2.5 9.1 7.3 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 CBZ32068.1 - 3 7.9 6.5 12 6.0 6.5 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 CBZ32068.1 - 6.8 7.2 13.6 3.8 8.0 9.6 2.3 2 1 1 3 3 3 0 Apg6 coiled-coil region LCAT PF02450.15 CBZ32069.1 - 7.5e-48 163.6 0.0 2e-36 126.0 0.1 2.2 1 1 1 2 2 2 2 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CBZ32069.1 - 5.3e-06 27.2 0.6 5.3e-06 27.2 0.6 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Motile_Sperm PF00635.26 CBZ32070.1 - 3.6e-11 42.9 0.0 6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain SHS2_Rpb7-N PF03876.17 CBZ32071.1 - 1.4e-25 89.4 0.0 2.6e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 CBZ32071.1 - 4e-11 43.3 0.0 5.3e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 GTP_EFTU PF00009.27 CBZ32072.1 - 1.5e-23 83.4 0.2 3.9e-23 82.0 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ32072.1 - 2.3e-05 24.5 0.0 0.00023 21.2 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ32072.1 - 0.00028 20.8 0.2 0.016 15.1 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CBZ32072.1 - 0.022 14.7 0.8 0.24 11.4 0.1 2.5 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 CBZ32072.1 - 0.023 14.7 0.4 0.46 10.5 0.1 2.3 1 1 0 2 2 2 0 Dynamin family FeoB_N PF02421.18 CBZ32072.1 - 0.048 13.2 0.2 10 5.6 0.1 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B Arf PF00025.21 CBZ32072.1 - 0.11 11.9 0.7 0.72 9.3 0.1 2.1 2 1 0 2 2 2 0 ADP-ribosylation factor family Zn-ribbon_8 PF09723.10 CBZ32072.1 - 0.27 11.4 4.8 0.65 10.2 4.8 1.7 1 0 0 1 1 1 0 Zinc ribbon domain IBR PF01485.21 CBZ32072.1 - 5.5 7.3 7.9 7.7 6.8 6.9 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Cnn_1N PF07989.11 CBZ32074.1 - 0.0013 18.8 6.4 0.02 15.0 0.1 3.4 3 1 0 3 3 3 1 Centrosomin N-terminal motif 1 DUF4201 PF13870.6 CBZ32074.1 - 0.0036 17.0 10.5 0.056 13.2 2.7 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Myosin_tail_1 PF01576.19 CBZ32074.1 - 0.0047 14.8 11.4 0.0061 14.4 11.4 1.1 1 0 0 1 1 1 1 Myosin tail CENP-Q PF13094.6 CBZ32074.1 - 0.0099 16.1 8.1 0.046 13.9 3.0 2.2 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit ABC_tran_CTD PF16326.5 CBZ32074.1 - 0.027 14.7 10.2 0.92 9.8 2.2 3.5 2 2 1 3 3 3 0 ABC transporter C-terminal domain Nas2_N PF18265.1 CBZ32074.1 - 0.038 13.9 4.3 0.8 9.7 0.0 3.0 3 0 0 3 3 3 0 Nas2 N_terminal domain DUF1993 PF09351.10 CBZ32074.1 - 0.045 13.9 7.4 0.042 14.0 5.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) FUSC PF04632.12 CBZ32074.1 - 0.12 10.9 6.2 0.27 9.7 6.3 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.19 CBZ32074.1 - 0.18 9.7 4.9 0.23 9.3 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_CLD_2 PF14197.6 CBZ32074.1 - 0.25 11.5 9.2 0.31 11.1 1.6 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 CBZ32074.1 - 0.25 11.8 12.8 6.5 7.3 1.2 3.5 3 0 0 3 3 3 0 Cell division protein ZapB HalX PF08663.10 CBZ32074.1 - 0.37 11.2 13.4 0.81 10.0 0.0 3.9 2 1 0 3 3 3 0 HalX domain DUF1151 PF06625.11 CBZ32074.1 - 0.37 10.7 6.6 5.7 6.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) GIT_CC PF16559.5 CBZ32074.1 - 0.6 10.0 8.9 0.62 10.0 2.0 3.7 2 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor CCDC144C PF14915.6 CBZ32074.1 - 0.64 9.1 14.4 0.68 9.0 13.5 1.3 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region SlyX PF04102.12 CBZ32074.1 - 0.68 10.6 11.8 14 6.4 0.0 3.6 3 1 0 3 3 3 0 SlyX Fez1 PF06818.15 CBZ32074.1 - 0.73 10.3 11.2 4.2 7.8 11.6 1.9 1 1 1 2 2 2 0 Fez1 Prominin PF05478.11 CBZ32074.1 - 1.1 7.2 7.6 6 4.7 0.5 1.9 1 1 1 2 2 2 0 Prominin Spectrin PF00435.21 CBZ32074.1 - 1.3 9.5 13.7 6.9 7.2 7.3 2.8 2 1 1 3 3 3 0 Spectrin repeat KASH_CCD PF14662.6 CBZ32074.1 - 1.3 8.8 14.6 0.1 12.4 3.1 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4570 PF15134.6 CBZ32074.1 - 1.4 8.9 7.5 4.5 7.3 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4570) zf-C4H2 PF10146.9 CBZ32074.1 - 2.2 8.6 7.9 2.4 8.4 5.9 1.8 1 1 1 2 2 2 0 Zinc finger-containing protein XhlA PF10779.9 CBZ32074.1 - 2.5 8.4 5.8 22 5.4 0.3 3.0 3 0 0 3 3 3 0 Haemolysin XhlA SOGA PF11365.8 CBZ32074.1 - 3.3 8.9 8.8 0.48 11.6 0.8 2.5 2 1 1 3 3 2 0 Protein SOGA DUF4200 PF13863.6 CBZ32074.1 - 3.4 8.1 13.2 1.7 9.1 4.5 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) TPR_MLP1_2 PF07926.12 CBZ32074.1 - 3.8 7.6 17.1 3 7.9 11.1 2.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 CBZ32074.1 - 4.2 6.6 14.7 1.7 7.9 11.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DHR10 PF18595.1 CBZ32074.1 - 4.5 7.4 18.5 0.96 9.5 4.5 2.9 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain DUF724 PF05266.14 CBZ32074.1 - 5.6 6.7 12.3 0.78 9.5 1.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF724) BST2 PF16716.5 CBZ32074.1 - 9.9 6.8 13.0 0.94 10.1 2.8 2.9 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 MRP PF09387.10 CBZ32076.1 - 2.1e-68 230.2 0.3 2.5e-68 229.9 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial RNA binding protein MRP Tim17 PF02466.19 CBZ32077.1 - 1.5e-16 60.7 9.8 2.2e-16 60.2 9.7 1.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family LMBR1 PF04791.16 CBZ32079.1 - 1.2 7.9 2.2 1.4 7.8 2.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein RRM_1 PF00076.22 CBZ32080.1 - 0.05 13.4 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Skp1 PF01466.19 CBZ32081.1 - 5.2e-07 29.7 0.3 1.2e-06 28.5 0.3 1.7 1 0 0 1 1 1 1 Skp1 family, dimerisation domain AP3D1 PF06375.11 CBZ32082.1 - 0.27 11.5 3.6 0.15 12.3 0.3 2.1 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 NOA36 PF06524.12 CBZ32082.1 - 1.2 8.4 6.0 2.9 7.1 6.0 1.6 1 0 0 1 1 1 0 NOA36 protein Reticulon PF02453.17 CBZ32083.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Reticulon Ank_4 PF13637.6 CBZ32084.1 - 0.013 16.1 0.1 0.18 12.5 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ32084.1 - 0.014 15.7 0.2 0.059 13.7 0.1 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ32084.1 - 0.014 16.0 0.5 0.26 11.9 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) ERAP1_C PF11838.8 CBZ32084.1 - 0.033 13.8 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Ank_3 PF13606.6 CBZ32084.1 - 0.1 13.2 0.0 0.73 10.6 0.0 2.6 1 0 0 1 1 1 0 Ankyrin repeat zf-C3HC4_3 PF13920.6 CBZ32085.1 - 1.3e-08 34.6 23.5 1.3e-08 34.6 23.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA PF00004.29 CBZ32086.1 - 2.1e-33 115.6 0.0 5.4e-22 78.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ32086.1 - 1.4e-08 35.3 3.3 1.7e-05 25.2 0.0 4.2 4 1 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 CBZ32086.1 - 2.6e-07 31.0 0.4 0.00098 19.4 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ32086.1 - 4.7e-07 30.1 0.0 0.0055 16.9 0.0 3.2 2 0 0 2 2 2 2 AAA domain Zot PF05707.12 CBZ32086.1 - 3.5e-06 26.8 1.0 0.092 12.4 0.0 4.1 2 2 2 4 4 4 2 Zonular occludens toxin (Zot) AAA_14 PF13173.6 CBZ32086.1 - 1e-05 25.6 0.0 0.00088 19.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CBZ32086.1 - 3.6e-05 23.2 0.1 0.019 14.1 0.1 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain IstB_IS21 PF01695.17 CBZ32086.1 - 5.1e-05 23.1 0.3 0.032 14.0 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 CBZ32086.1 - 5.8e-05 23.1 0.0 0.0072 16.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBZ32086.1 - 6.9e-05 22.4 0.4 0.0011 18.5 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CBZ32086.1 - 0.00011 22.5 0.0 0.034 14.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF2075 PF09848.9 CBZ32086.1 - 0.00014 21.2 0.1 0.63 9.2 0.0 3.2 2 1 1 3 3 3 2 Uncharacterized conserved protein (DUF2075) Bac_DnaA PF00308.18 CBZ32086.1 - 0.00036 20.5 0.2 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein RuvB_N PF05496.12 CBZ32086.1 - 0.00093 19.0 0.0 0.051 13.3 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CBZ32086.1 - 0.0015 18.5 0.1 0.065 13.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 CBZ32086.1 - 0.0015 19.1 0.0 0.096 13.2 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Torsin PF06309.11 CBZ32086.1 - 0.0016 18.6 0.1 0.11 12.5 0.1 2.6 2 0 0 2 2 2 1 Torsin Sigma54_activat PF00158.26 CBZ32086.1 - 0.0017 18.1 0.1 0.68 9.6 0.1 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 CBZ32086.1 - 0.0021 17.8 0.0 0.14 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBZ32086.1 - 0.0051 16.2 0.3 0.059 12.7 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CBZ32086.1 - 0.01 16.4 0.0 0.97 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBZ32086.1 - 0.018 14.5 1.8 0.2 11.1 0.0 2.8 2 1 1 3 3 3 0 PhoH-like protein AAA_2 PF07724.14 CBZ32086.1 - 0.02 15.0 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) APS_kinase PF01583.20 CBZ32086.1 - 0.027 14.4 0.1 0.43 10.5 0.1 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 CBZ32086.1 - 0.038 13.9 0.1 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase SRP54 PF00448.22 CBZ32086.1 - 0.043 13.4 0.2 0.24 11.0 0.0 2.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CBZ32086.1 - 0.047 13.4 0.9 3.4 7.5 0.3 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 CBZ32086.1 - 0.058 12.5 0.0 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 CBZ32086.1 - 0.065 12.4 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 1 0 NB-ARC domain TsaE PF02367.17 CBZ32086.1 - 0.077 13.0 0.3 0.41 10.7 0.2 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 CBZ32086.1 - 0.095 12.0 0.2 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 KaiC Microtub_bd PF16796.5 CBZ32086.1 - 0.21 11.5 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Microtubule binding DLP_helical PF18709.1 CBZ32087.1 - 0.055 12.7 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain AAA_11 PF13086.6 CBZ32088.1 - 1.9e-13 50.8 0.2 1.3e-12 48.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBZ32088.1 - 0.014 15.7 0.0 0.046 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CBZ32088.1 - 0.016 15.5 0.0 0.062 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 CBZ32088.1 - 0.02 14.7 0.0 0.086 12.7 0.0 2.1 1 0 0 1 1 1 0 Helicase Bromodomain PF00439.25 CBZ32090.1 - 6.4e-22 77.4 0.0 2.3e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 Bromodomain BSD PF03909.17 CBZ32090.1 - 0.11 12.5 0.0 16 5.6 0.0 2.5 2 0 0 2 2 2 0 BSD domain Mito_carr PF00153.27 CBZ32091.1 - 7.2e-43 144.4 6.3 2.5e-17 62.6 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DZR PF12773.7 CBZ32092.1 - 9e-05 22.4 1.0 0.023 14.7 0.1 2.6 2 1 0 2 2 2 2 Double zinc ribbon HypA PF01155.19 CBZ32092.1 - 0.0095 15.9 0.1 0.52 10.3 0.0 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_10 PF10058.9 CBZ32092.1 - 0.035 13.9 3.5 6.3 6.6 0.2 3.9 4 0 0 4 4 4 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-FPG_IleRS PF06827.14 CBZ32092.1 - 0.094 12.6 1.0 13 5.8 0.1 2.9 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Nucleocap_ssRNA PF11128.8 CBZ32092.1 - 0.29 10.8 0.6 0.7 9.6 0.6 1.6 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid zf_UBZ PF18439.1 CBZ32092.1 - 0.35 10.5 3.6 44 3.8 0.2 3.5 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-LITAF-like PF10601.9 CBZ32092.1 - 0.73 10.1 6.3 20 5.5 0.0 3.8 3 1 0 4 4 4 0 LITAF-like zinc ribbon domain Zn-ribbon_8 PF09723.10 CBZ32092.1 - 1.3 9.2 5.7 2.5 8.3 0.2 2.8 2 1 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 CBZ32092.1 - 9.2 6.3 11.5 23 5.1 0.1 3.9 4 0 0 4 4 4 0 Transposase zinc-ribbon domain Kelch_4 PF13418.6 CBZ32093.1 - 1e-09 38.2 0.7 0.81 9.7 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ32093.1 - 1.8e-05 24.6 11.4 0.22 11.5 0.4 6.0 6 1 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CBZ32093.1 - 0.0012 18.7 1.0 13 5.9 0.0 5.0 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.6 CBZ32093.1 - 0.16 12.3 0.3 15 6.1 0.0 4.0 5 0 0 5 5 5 0 Kelch motif Peptidase_C97 PF05903.14 CBZ32094.1 - 3.6e-25 88.6 0.1 1.6e-24 86.4 0.0 1.8 1 1 1 2 2 2 1 PPPDE putative peptidase domain DUF4796 PF16044.5 CBZ32094.1 - 0.02 14.5 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Peptidase_C97 PF05903.14 CBZ32095.1 - 4.7e-23 81.7 0.0 6.9e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4796 PF16044.5 CBZ32095.1 - 0.048 13.3 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Flagellar_rod PF05149.12 CBZ32097.1 - 4.1e-110 367.8 23.8 4.1e-110 367.8 23.8 1.8 2 0 0 2 2 2 1 Paraflagellar rod protein Glutaredoxin2_C PF04399.13 CBZ32097.1 - 0.023 14.5 8.5 0.1 12.4 1.3 3.3 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain THUMP PF02926.17 CBZ32097.1 - 0.067 13.3 2.1 9.4 6.3 0.0 2.9 2 1 0 2 2 2 0 THUMP domain Helo_like_N PF17111.5 CBZ32097.1 - 0.081 12.3 0.0 0.081 12.3 0.0 3.0 2 1 1 3 3 3 0 Fungal N-terminal domain of STAND proteins Aminotran_4 PF01063.19 CBZ32097.1 - 0.2 11.5 1.4 0.54 10.1 0.1 2.2 1 1 1 2 2 2 0 Amino-transferase class IV HBD PF18534.1 CBZ32097.1 - 0.23 11.6 3.1 1.9 8.6 0.2 3.4 1 1 1 2 2 2 0 Helical bundle domain CPSF100_C PF13299.6 CBZ32097.1 - 1.6 8.9 7.7 0.34 11.1 3.5 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Plk4_PB2 PF18409.1 CBZ32097.1 - 7.5 7.3 9.4 11 6.8 0.1 3.7 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 2 Histone PF00125.24 CBZ32099.1 - 1.2e-10 41.8 0.5 1.6e-10 41.4 0.5 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ32099.1 - 0.0024 18.1 0.3 0.0043 17.3 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GMP_synt_C PF00958.22 CBZ32099.1 - 0.15 12.1 1.4 0.21 11.6 0.9 1.4 1 1 0 1 1 1 0 GMP synthase C terminal domain zf-SAP30 PF13866.6 CBZ32101.1 - 0.12 12.5 0.3 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 SAP30 zinc-finger F-box PF00646.33 CBZ32104.1 - 0.11 12.4 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 CBZ32104.1 - 1.8 8.5 5.6 0.44 10.5 0.1 2.7 3 0 0 3 3 3 0 F-box-like Glyco_hydro_47 PF01532.20 CBZ32105.1 - 1.7e-05 23.9 0.0 2.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SET PF00856.28 CBZ32106.1 - 6.2e-10 39.7 0.0 1.5e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 SET domain Trigger_C PF05698.14 CBZ32107.1 - 0.00029 20.9 1.6 0.00029 20.9 1.6 2.1 1 1 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus DUF4296 PF14129.6 CBZ32107.1 - 0.0099 16.5 1.4 0.34 11.5 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4296) KORA PF16509.5 CBZ32107.1 - 0.035 14.4 1.5 0.057 13.7 1.3 1.6 1 1 0 1 1 1 0 TrfB plasmid transcriptional repressor Prominin PF05478.11 CBZ32107.1 - 0.085 10.8 1.1 0.097 10.6 1.1 1.1 1 0 0 1 1 1 0 Prominin DUF1128 PF06569.11 CBZ32107.1 - 0.094 12.7 2.5 2.9 7.9 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1128) Presenilin PF01080.17 CBZ32107.1 - 0.16 10.7 6.9 0.19 10.4 6.9 1.0 1 0 0 1 1 1 0 Presenilin Eisosome1 PF12757.7 CBZ32107.1 - 0.2 11.9 14.1 37 4.6 14.1 2.3 1 1 0 1 1 1 0 Eisosome protein 1 DUF1318 PF07027.12 CBZ32107.1 - 0.22 12.0 3.3 0.2 12.1 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1318) L31 PF09784.9 CBZ32107.1 - 0.33 11.4 5.6 0.1 13.0 2.6 1.7 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 DUF4951 PF16309.5 CBZ32107.1 - 0.41 10.7 2.2 8.2 6.5 0.1 2.8 1 1 2 3 3 3 0 Domian of unknown function (DUF4951) Tho2 PF11262.8 CBZ32107.1 - 0.66 9.1 8.0 0.19 10.9 5.4 1.3 1 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4168 PF13767.6 CBZ32107.1 - 0.68 11.1 7.4 0.43 11.8 5.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4168) YtxH PF12732.7 CBZ32107.1 - 1.7 9.2 7.7 13 6.4 0.5 2.3 1 1 1 2 2 2 0 YtxH-like protein DUF4407 PF14362.6 CBZ32107.1 - 4.4 6.6 7.3 6.2 6.1 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Coq4 PF05019.13 CBZ32108.1 - 1.1e-48 165.5 0.0 1.2e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 PCSK9_C2 PF18464.1 CBZ32108.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain DnaJ PF00226.31 CBZ32110.1 - 8.1e-12 45.1 0.1 1.7e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain PHA_synth_III_E PF09712.10 CBZ32110.1 - 0.0023 17.1 1.1 0.008 15.3 0.3 1.8 2 0 0 2 2 2 1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) GcrA PF07750.11 CBZ32110.1 - 0.015 15.8 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 GcrA cell cycle regulator P4Ha_N PF08336.11 CBZ32110.1 - 0.11 12.5 0.2 0.3 11.1 0.2 1.7 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Rhodanese PF00581.20 CBZ32111.1 - 2.6e-05 24.7 0.0 3e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 CBZ32112.1 - 2.5e-11 44.1 0.0 3.5e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain S8_pro-domain PF16470.5 CBZ32112.1 - 0.062 14.1 0.0 0.1 13.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase S8 pro-domain HTH_18 PF12833.7 CBZ32112.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Rhodanese PF00581.20 CBZ32113.1 - 5.8e-15 55.7 0.0 6.9e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF4859 PF16151.5 CBZ32113.1 - 0.061 13.2 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4859) Mito_carr PF00153.27 CBZ32113.1 - 0.19 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial carrier protein DB_JBP1 PF18526.1 CBZ32114.1 - 1.3e-85 285.3 8.4 1.8e-85 284.9 4.4 2.2 2 0 0 2 2 2 1 Thymine dioxygenase JBP1 DNA-binding domain Tet_JBP PF12851.7 CBZ32114.1 - 4.1e-20 72.4 0.0 5e-16 59.0 0.0 2.3 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily B2-adapt-app_C PF09066.10 CBZ32114.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain TRAP-delta PF05404.12 CBZ32114.1 - 0.041 13.4 0.8 0.41 10.2 0.7 2.3 2 0 0 2 2 2 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) Cyt-b5 PF00173.28 CBZ32115.1 - 9.4e-21 73.7 0.3 1.2e-20 73.4 0.3 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 CBZ32116.1 - 6.9e-15 55.0 0.1 1.6e-14 53.7 0.1 1.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IQ PF00612.27 CBZ32118.1 - 0.017 14.9 0.0 0.058 13.2 0.0 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif CPT PF07931.12 CBZ32118.1 - 0.06 13.2 0.7 0.16 11.8 0.7 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein UPF0180 PF03698.13 CBZ32118.1 - 0.12 12.5 0.0 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) Rtf2 PF04641.12 CBZ32118.1 - 1.9 7.8 7.6 3.3 7.0 7.6 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger LRR_6 PF13516.6 CBZ32119.1 - 5.1e-16 57.3 2.4 0.033 14.2 0.0 7.6 8 0 0 8 8 8 3 Leucine Rich repeat EF-hand_6 PF13405.6 CBZ32120.1 - 0.002 17.9 0.0 0.13 12.3 0.0 3.1 1 1 1 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CBZ32120.1 - 0.0047 17.3 0.0 0.0083 16.6 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ32120.1 - 0.031 13.8 0.0 0.27 10.9 0.0 2.5 3 0 0 3 3 3 0 EF hand DUF3294 PF07957.11 CBZ32120.1 - 0.079 12.7 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) RIIa PF02197.17 CBZ32120.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit KASH_CCD PF14662.6 CBZ32121.1 - 0.0019 18.0 85.9 0.048 13.5 20.0 5.3 2 2 2 5 5 5 4 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 CBZ32121.1 - 1.2 9.3 97.5 0.31 11.2 16.4 6.0 1 1 4 5 5 5 0 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 CBZ32121.1 - 3.1 7.2 80.6 1.1 8.6 7.0 5.1 2 2 3 5 5 5 0 Hyaluronan mediated motility receptor N-terminal DUF4257 PF14074.6 CBZ32122.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4257) Wzy_C PF04932.15 CBZ32122.1 - 0.19 11.4 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF4333 PF14230.6 CBZ32123.1 - 0.22 11.8 2.1 1.1 9.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4333) MMS19_N PF14500.6 CBZ32124.1 - 1.4e-43 149.4 2.9 3.8e-43 148.0 2.9 1.8 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.8 CBZ32124.1 - 0.013 15.1 0.1 0.054 13.1 0.1 2.1 1 0 0 1 1 1 0 CLASP N terminal Kdo PF06293.14 CBZ32124.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMS19_N PF14500.6 CBZ32125.1 - 1.4e-43 149.4 2.9 3.8e-43 148.0 2.9 1.8 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II CLASP_N PF12348.8 CBZ32125.1 - 0.013 15.1 0.1 0.054 13.1 0.1 2.1 1 0 0 1 1 1 0 CLASP N terminal Kdo PF06293.14 CBZ32125.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thymidylate_kin PF02223.17 CBZ32126.1 - 4.8e-15 55.7 0.0 1.6e-14 54.0 0.0 1.8 1 1 0 1 1 1 1 Thymidylate kinase dNK PF01712.19 CBZ32126.1 - 0.17 11.7 0.0 0.96 9.3 0.0 2.0 1 1 0 1 1 1 0 Deoxynucleoside kinase adh_short PF00106.25 CBZ32128.1 - 3.3e-30 105.0 0.0 1.6e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ32128.1 - 7.2e-19 68.3 0.0 1.9e-14 53.8 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ32128.1 - 2.6e-05 24.2 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ32128.1 - 0.0001 21.9 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBZ32128.1 - 0.021 14.3 0.0 0.045 13.2 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CBZ32128.1 - 0.023 14.6 0.0 0.08 12.8 0.0 2.0 1 1 0 1 1 1 0 NAD(P)H-binding PDE6_gamma PF04868.12 CBZ32128.1 - 0.34 11.2 2.0 14 6.0 0.0 3.1 2 1 1 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit SRP40_C PF05022.12 CBZ32129.1 - 3.3e-12 47.1 0.5 6.4e-12 46.2 0.5 1.5 1 0 0 1 1 1 1 SRP40, C-terminal domain DUF4692 PF15763.5 CBZ32129.1 - 6.7 7.2 12.1 0.3 11.5 0.9 2.3 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) WD40 PF00400.32 CBZ32130.1 - 7e-28 96.3 28.5 1.4e-06 28.9 0.4 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ32130.1 - 0.00011 22.4 0.2 0.045 14.1 0.0 4.0 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PSP1 PF04468.12 CBZ32131.1 - 5.2e-23 81.1 0.3 7.8e-23 80.6 0.3 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PLU-1 PF08429.11 CBZ32132.1 - 0.0014 17.9 5.6 0.0023 17.2 5.6 1.2 1 0 0 1 1 1 1 PLU-1-like protein BLOC1_2 PF10046.9 CBZ32132.1 - 0.097 13.0 9.0 1.4 9.3 0.9 2.4 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Gag_p6 PF08705.11 CBZ32132.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.4 3 0 0 3 3 3 0 Gag protein p6 FlxA PF14282.6 CBZ32132.1 - 1.2 9.2 12.8 1.2 9.2 5.9 2.8 1 1 1 2 2 2 0 FlxA-like protein NPV_P10 PF05531.12 CBZ32132.1 - 1.6 9.3 6.7 11 6.5 0.5 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 CBZ32132.1 - 2 9.0 9.8 1.3 9.6 2.4 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 Spectrin PF00435.21 CBZ32132.1 - 2.6 8.6 15.8 5.4 7.6 7.3 3.2 2 1 1 3 3 3 0 Spectrin repeat SHE3 PF17078.5 CBZ32132.1 - 2.9 7.6 8.5 0.23 11.1 3.1 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 Snapin_Pallidin PF14712.6 CBZ32132.1 - 3.4 8.2 12.1 9.1 6.8 8.1 2.5 1 1 0 2 2 2 0 Snapin/Pallidin PI3K_P85_iSH2 PF16454.5 CBZ32132.1 - 9 5.9 14.9 0.97 9.0 8.1 2.5 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DEAD PF00270.29 CBZ32133.1 - 5.7e-18 65.3 0.1 2.4e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ32133.1 - 2.6e-13 50.3 0.2 7.4e-13 48.8 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UTP25 PF06862.12 CBZ32133.1 - 0.0099 14.7 0.1 7.2 5.2 0.0 3.3 4 0 0 4 4 4 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Spc7 PF08317.11 CBZ32135.1 - 0.0031 16.5 19.3 0.0031 16.5 19.3 2.2 2 0 0 2 2 2 1 Spc7 kinetochore protein ARGLU PF15346.6 CBZ32135.1 - 0.3 10.9 41.2 1.3 8.9 22.3 2.4 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DUF2046 PF09755.9 CBZ32135.1 - 0.96 8.6 40.1 0.023 14.0 25.9 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF4250 PF14056.6 CBZ32135.1 - 1.1 9.3 5.3 0.55 10.2 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) MipZ PF09140.11 CBZ32135.1 - 2.1 7.5 8.4 0.17 11.1 1.7 2.2 2 1 0 2 2 2 0 ATPase MipZ DUF3584 PF12128.8 CBZ32135.1 - 3.4 5.1 36.2 1.2 6.6 20.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Arm-DNA-bind_2 PF12167.8 CBZ32135.1 - 3.4 7.6 4.6 2.2 8.2 0.4 2.8 3 0 0 3 3 3 0 Arm DNA-binding domain Tropomyosin_1 PF12718.7 CBZ32135.1 - 3.7 7.7 41.9 1 9.5 8.3 3.1 3 0 0 3 3 3 0 Tropomyosin like NPV_P10 PF05531.12 CBZ32135.1 - 4.5 7.8 13.8 2.5 8.6 5.2 3.6 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Ribosomal_S15 PF00312.22 CBZ32135.1 - 4.8 7.5 15.0 0.11 12.8 6.8 2.4 2 1 0 2 2 2 0 Ribosomal protein S15 APG6_N PF17675.1 CBZ32135.1 - 5.8 7.5 49.8 0.49 10.9 22.2 3.1 2 1 1 3 3 3 0 Apg6 coiled-coil region TMPIT PF07851.13 CBZ32135.1 - 7.7 5.7 23.6 4.3 6.5 3.5 2.5 2 1 0 2 2 2 0 TMPIT-like protein CENP-K PF11802.8 CBZ32135.1 - 8.8 5.8 24.9 8.9 5.8 15.0 2.2 2 0 0 2 2 2 0 Centromere-associated protein K GDA1_CD39 PF01150.17 CBZ32136.1 - 3.4e-65 220.4 0.0 7.1e-65 219.3 0.0 1.5 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CBZ32136.1 - 0.023 14.1 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 Ppx/GppA phosphatase family LRR_8 PF13855.6 CBZ32137.1 - 1.7e-12 46.9 13.9 2e-07 30.6 10.7 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBZ32137.1 - 8.8e-12 45.1 12.8 2.6e-05 24.5 1.6 3.3 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ32137.1 - 3.7e-06 26.7 9.7 18 6.4 0.0 5.8 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_9 PF14580.6 CBZ32137.1 - 0.058 12.9 0.3 0.085 12.4 0.3 1.3 1 0 0 1 1 1 0 Leucine-rich repeat PDZ_6 PF17820.1 CBZ32139.1 - 1.5e-09 37.5 0.1 4.3e-09 36.1 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBZ32139.1 - 6e-05 23.3 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBZ32139.1 - 0.00012 22.3 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain MORN PF02493.20 CBZ32140.1 - 5.9e-19 66.8 15.6 3.2e-05 23.6 1.1 4.6 4 0 0 4 4 4 4 MORN repeat ECR1_N PF14382.6 CBZ32140.1 - 0.43 10.4 3.0 9.1 6.2 1.0 3.0 2 1 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region Pkinase PF00069.25 CBZ32141.1 - 1.8e-57 194.7 0.0 2.3e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32141.1 - 2.6e-27 95.7 0.0 4.4e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBZ32141.1 - 5.9e-07 28.8 0.6 8.2e-07 28.3 0.6 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBZ32141.1 - 2.8e-05 23.6 1.2 5.4e-05 22.6 1.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ32141.1 - 0.00012 22.1 0.2 0.00012 22.1 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ32141.1 - 0.026 14.1 0.7 0.21 11.2 0.4 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 CBZ32141.1 - 0.031 13.1 0.5 0.054 12.3 0.5 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 CBZ32141.1 - 0.087 12.1 0.1 0.2 10.9 0.1 1.9 1 1 0 1 1 1 0 Kinase-like Nop PF01798.18 CBZ32142.1 - 1e-79 267.3 0.0 1.5e-79 266.8 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CBZ32142.1 - 1.5e-16 60.5 0.0 4.2e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Amastin PF07344.11 CBZ32145.1 - 1.8e-38 131.8 22.8 1.8e-23 83.1 5.5 2.3 2 0 0 2 2 2 2 Amastin surface glycoprotein Amastin PF07344.11 CBZ32146.1 - 3.9e-54 182.7 15.1 2e-36 125.2 6.2 2.2 2 0 0 2 2 2 2 Amastin surface glycoprotein MNSV_P7B PF06692.11 CBZ32146.1 - 5.9 7.0 6.4 1.9 8.6 0.1 3.1 3 0 0 3 3 3 0 Melon necrotic spot virus P7B protein CaM_binding PF07839.11 CBZ32147.1 - 0.19 12.5 4.8 0.23 12.2 2.7 2.2 2 0 0 2 2 2 0 Plant calmodulin-binding domain Pterin_4a PF01329.19 CBZ32148.1 - 1.9e-09 37.6 0.0 1.1e-08 35.1 0.0 2.3 2 1 0 2 2 2 1 Pterin 4 alpha carbinolamine dehydratase DUF5073 PF16817.5 CBZ32148.1 - 0.055 13.5 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5073) COPI_assoc PF08507.10 CBZ32149.1 - 1.1e-06 28.7 18.3 1.4e-06 28.4 18.3 1.1 1 0 0 1 1 1 1 COPI associated protein Herpes_US12 PF05363.12 CBZ32150.1 - 0.025 15.3 0.2 0.11 13.3 0.2 2.1 1 0 0 1 1 1 0 Herpesvirus US12 family Toprim_2 PF13155.6 CBZ32151.1 - 0.011 16.2 1.5 4.9 7.6 0.0 3.3 2 0 0 2 2 2 0 Toprim-like SlyX PF04102.12 CBZ32151.1 - 9.1 7.0 8.8 1e+02 3.6 0.1 4.9 4 0 0 4 4 4 0 SlyX Iso_dh PF00180.20 CBZ32152.1 - 1.3e-73 248.1 0.0 1.5e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Vps5 PF09325.10 CBZ32153.1 - 0.058 12.9 6.0 0.11 12.1 6.0 1.3 1 0 0 1 1 1 0 Vps5 C terminal like ComX PF05952.12 CBZ32153.1 - 0.15 12.0 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Bacillus competence pheromone ComX SEN1_N PF12726.7 CBZ32153.1 - 0.15 10.2 2.2 0.17 10.0 1.0 1.6 2 0 0 2 2 2 0 SEN1 N terminal DUF16 PF01519.16 CBZ32153.1 - 0.35 11.4 2.8 0.76 10.3 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 CBZ32153.1 - 0.43 10.1 10.3 0.94 9.0 10.3 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0242 PF06785.11 CBZ32153.1 - 0.61 10.2 7.5 1.2 9.2 7.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V_ATPase_I PF01496.19 CBZ32153.1 - 0.81 7.5 4.4 1.2 7.0 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 CBZ32153.1 - 0.98 8.2 6.1 1.5 7.5 6.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF3584 PF12128.8 CBZ32153.1 - 1.1 6.7 14.8 1.6 6.2 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.9 CBZ32153.1 - 2.4 7.2 7.8 3.8 6.5 7.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc24 PF08286.11 CBZ32153.1 - 4.4 7.6 7.5 6.9 7.0 6.8 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Sec23_trunk PF04811.15 CBZ32154.1 - 1.6e-40 139.2 0.0 2e-20 73.4 0.0 2.2 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CBZ32154.1 - 6.3e-20 70.9 0.0 2e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CBZ32154.1 - 1.2e-19 70.8 0.0 2.4e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CBZ32154.1 - 6.5e-07 29.2 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Ima1_N PF09779.9 CBZ32154.1 - 0.05 14.5 0.6 0.093 13.6 0.6 1.4 1 0 0 1 1 1 0 Ima1 N-terminal domain zf-Sec23_Sec24 PF04810.15 CBZ32154.1 - 0.075 13.1 8.2 0.16 12.0 8.2 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger ThiC_Rad_SAM PF01964.18 CBZ32154.1 - 0.52 9.0 4.1 0.23 10.2 0.1 2.0 2 0 0 2 2 2 0 Radical SAM ThiC family Vps36-NZF-N PF16988.5 CBZ32154.1 - 0.95 8.9 3.4 0.28 10.6 0.1 1.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain SinI PF08671.10 CBZ32156.1 - 0.77 9.6 2.0 1.3 8.9 2.0 1.3 1 0 0 1 1 1 0 Anti-repressor SinI BT1 PF03092.16 CBZ32157.1 - 4.8e-201 668.5 9.8 5.6e-201 668.3 9.8 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 CBZ32158.1 - 4.3e-264 876.6 3.4 4.9e-264 876.4 3.4 1.0 1 0 0 1 1 1 1 BT1 family GPI2 PF06432.11 CBZ32158.1 - 7.5 5.9 9.8 1.2 8.5 4.4 2.4 1 1 1 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase BT1 PF03092.16 CBZ32159.1 - 3.5e-40 137.7 1.4 4.2e-40 137.5 1.4 1.1 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 CBZ32160.1 - 4.6e-105 351.8 0.2 5.5e-105 351.6 0.2 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 CBZ32161.1 - 5.1e-128 427.6 0.0 5.8e-128 427.4 0.0 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 CBZ32162.1 - 4.7e-108 361.7 0.0 5.7e-108 361.4 0.0 1.0 1 0 0 1 1 1 1 BT1 family BT1 PF03092.16 CBZ32163.1 - 1.5e-264 878.1 5.7 1.8e-264 877.9 5.7 1.0 1 0 0 1 1 1 1 BT1 family DUF4044 PF13253.6 CBZ32163.1 - 2.7 7.6 5.5 12 5.6 5.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Dak1 PF02733.17 CBZ32164.1 - 5.8e-92 307.9 0.9 5.8e-92 307.9 0.9 1.6 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 CBZ32164.1 - 1.9e-37 128.8 3.5 1.9e-37 128.8 3.5 1.8 2 0 0 2 2 2 1 DAK2 domain zf-C3HC4_3 PF13920.6 CBZ32166.1 - 6.1e-05 22.8 15.2 6.1e-05 22.8 15.2 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ32166.1 - 0.23 11.4 12.5 0.53 10.3 12.5 1.6 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBZ32167.1 - 1.8e-06 27.7 17.2 8.4e-06 25.5 17.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ32167.1 - 0.055 13.4 13.4 0.12 12.4 13.4 1.6 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 CBZ32167.1 - 2.4 8.1 15.9 28 4.7 15.9 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 4F5 PF04419.14 CBZ32168.1 - 9.7e-10 39.2 8.2 1.5e-09 38.6 8.2 1.3 1 0 0 1 1 1 1 4F5 protein family zf-met2 PF12907.7 CBZ32168.1 - 1.1e-06 28.7 1.1 1.1e-06 28.7 1.1 1.7 2 0 0 2 2 2 1 Zinc-binding zf-H2C2_2 PF13465.6 CBZ32168.1 - 0.075 13.5 1.4 0.3 11.6 0.4 2.3 2 1 0 2 2 2 0 Zinc-finger double domain DUF3504 PF12012.8 CBZ32168.1 - 0.086 12.7 0.9 0.095 12.6 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) Fer4_18 PF13746.6 CBZ32168.1 - 0.1 12.8 1.7 0.11 12.7 1.7 1.2 1 0 0 1 1 1 0 4Fe-4S dicluster domain zf-C2H2_4 PF13894.6 CBZ32168.1 - 0.12 13.2 1.5 0.62 11.0 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M8 PF01457.16 CBZ32169.1 - 2.3e-12 46.4 0.1 2.8e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Leishmanolysin DUF1726 PF08351.11 CBZ32171.1 - 0.0077 16.1 0.0 0.011 15.7 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1726) Pkinase PF00069.25 CBZ32172.1 - 1.5e-63 214.7 0.0 1.7e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32172.1 - 1.4e-27 96.6 0.0 8.5e-27 94.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ32172.1 - 0.0025 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBZ32172.1 - 0.0034 16.8 0.1 0.0056 16.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Baculo_11_kDa PF06143.11 CBZ32173.1 - 0.78 9.4 2.4 1.7 8.3 2.4 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Thionin PF00321.17 CBZ32173.1 - 1.1 9.8 3.6 50 4.5 0.1 3.4 2 0 0 2 2 2 0 Plant thionin NAD_Gly3P_dh_C PF07479.14 CBZ32174.1 - 2.6e-46 157.5 0.6 2.6e-46 157.5 0.6 2.0 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 CBZ32174.1 - 1.4e-43 148.6 0.2 2.5e-43 147.8 0.0 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 CBZ32174.1 - 0.00022 20.8 0.0 0.00041 20.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 CBZ32174.1 - 0.0054 17.3 0.0 0.013 16.1 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1188 PF06690.11 CBZ32174.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) NAD_binding_2 PF03446.15 CBZ32174.1 - 0.0085 16.3 0.0 0.049 13.8 0.0 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CBZ32174.1 - 0.11 12.4 0.1 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA_C PF08546.11 CBZ32174.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DUF1281 PF06924.11 CBZ32176.1 - 0.0035 16.9 0.4 0.031 13.8 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1281) DUF2347 PF09804.9 CBZ32176.1 - 0.14 11.7 0.0 0.14 11.7 0.0 4.7 3 1 0 4 4 4 0 Uncharacterized conserved protein (DUF2347) DUF4145 PF13643.6 CBZ32176.1 - 0.42 10.8 14.3 1.4 9.1 0.1 5.0 4 2 1 5 5 5 0 Domain of unknown function (DUF4145) FAD_SOX PF18371.1 CBZ32176.1 - 0.82 10.1 5.2 1.9 8.9 0.1 4.0 3 0 0 3 3 3 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Cas_DxTHG PF09455.10 CBZ32176.1 - 2.4 7.7 11.1 1.3 8.5 0.1 3.0 2 2 0 2 2 2 0 CRISPR-associated (Cas) DxTHG family Pox_A_type_inc PF04508.12 CBZ32176.1 - 5.5 7.0 11.3 0.22 11.4 1.1 3.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat ADH_zinc_N PF00107.26 CBZ32179.1 - 2.2e-15 56.8 0.0 4e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBZ32179.1 - 1.2e-08 36.0 0.0 2.1e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ32179.1 - 4.2e-08 33.1 0.2 1.5e-07 31.3 0.2 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cupin_2 PF07883.11 CBZ32179.1 - 0.072 12.8 0.3 0.18 11.6 0.2 1.7 2 0 0 2 2 2 0 Cupin domain ADH_zinc_N PF00107.26 CBZ32180.1 - 1.1e-17 64.3 0.0 2e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBZ32180.1 - 2.3e-13 51.4 0.1 2.3e-13 51.4 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ32180.1 - 0.00068 19.5 0.0 0.0024 17.7 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CAF1A PF12253.8 CBZ32181.1 - 1.5e-08 34.7 1.1 1.5e-08 34.7 1.1 3.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A ABC1 PF03109.16 CBZ32183.1 - 1e-22 80.5 0.0 6.5e-22 77.9 0.0 2.1 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.25 CBZ32183.1 - 0.055 12.8 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Endonuclease_NS PF01223.23 CBZ32184.1 - 1.4e-50 172.2 0.0 2.8e-50 171.3 0.0 1.4 1 1 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 CBZ32184.1 - 0.053 13.6 0.1 0.15 12.2 0.1 1.7 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease Cytomega_UL20A PF05984.12 CBZ32184.1 - 0.15 12.4 0.6 0.32 11.3 0.6 1.5 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein DUF4667 PF15700.5 CBZ32186.1 - 0.0013 18.9 2.0 0.0018 18.4 2.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) Apt1 PF10351.9 CBZ32186.1 - 0.12 11.3 0.7 0.14 11.0 0.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AF-4 PF05110.13 CBZ32186.1 - 0.21 9.7 18.5 0.28 9.2 18.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RAP1 PF07218.11 CBZ32186.1 - 3.5 5.8 11.1 4.8 5.4 11.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF4614 PF15391.6 CBZ32186.1 - 3.9 7.4 10.1 7.3 6.6 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.9 CBZ32186.1 - 6.1 5.3 8.3 8.5 4.8 8.3 1.1 1 0 0 1 1 1 0 Macoilin family zf-CCCH PF00642.24 CBZ32187.1 - 0.013 15.4 2.3 0.022 14.7 2.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ32187.1 - 0.35 11.0 3.0 0.61 10.2 3.0 1.4 1 0 0 1 1 1 0 Zinc finger domain DUF1751 PF08551.10 CBZ32190.1 - 0.00053 20.5 1.3 0.0038 17.8 0.5 2.3 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) DUF2583 PF10762.9 CBZ32190.1 - 0.079 13.4 0.4 0.24 11.8 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) Paf1 PF03985.13 CBZ32190.1 - 1.9 7.4 6.3 2.5 7.0 6.3 1.0 1 0 0 1 1 1 0 Paf1 HEAT PF02985.22 CBZ32192.1 - 0.0015 18.6 39.8 0.012 15.8 0.1 9.3 9 0 0 9 9 9 3 HEAT repeat TetR_C_36 PF18598.1 CBZ32192.1 - 0.016 15.2 1.2 2 8.4 0.1 3.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HEAT_2 PF13646.6 CBZ32192.1 - 0.13 12.7 29.2 0.27 11.6 0.1 8.5 8 1 0 8 8 8 0 HEAT repeats RRM_1 PF00076.22 CBZ32193.1 - 4.6e-43 144.9 2.1 2.2e-15 56.2 0.0 6.3 6 1 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ32193.1 - 2.3e-07 30.5 0.0 0.0015 18.1 0.0 3.8 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ32193.1 - 1.6e-06 27.9 0.0 0.0087 15.9 0.0 3.8 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CBZ32193.1 - 0.007 16.5 0.0 0.095 12.8 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif RRM_Rrp7 PF17799.1 CBZ32193.1 - 0.013 15.3 0.1 2.9 7.7 0.0 3.6 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain XS PF03468.14 CBZ32193.1 - 0.33 11.3 1.0 5.2 7.4 0.0 2.8 3 0 0 3 3 3 0 XS domain Aa_trans PF01490.18 CBZ32194.1 - 4.1e-40 137.8 36.0 6.7e-40 137.0 36.0 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SLC3A2_N PF16028.5 CBZ32194.1 - 0.22 11.1 0.1 0.22 11.1 0.1 3.2 2 1 1 3 3 3 0 Solute carrier family 3 member 2 N-terminus Aa_trans PF01490.18 CBZ32195.1 - 4.1e-40 137.8 36.0 6.7e-40 137.0 36.0 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein SLC3A2_N PF16028.5 CBZ32195.1 - 0.22 11.1 0.1 0.22 11.1 0.1 3.2 2 1 1 3 3 3 0 Solute carrier family 3 member 2 N-terminus dCMP_cyt_deam_1 PF00383.23 CBZ32196.1 - 1.1e-12 47.7 0.2 1.7e-10 40.7 0.2 2.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CBZ32196.1 - 1.2e-11 44.5 0.6 1.6e-05 24.7 0.0 3.1 2 1 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 CBZ32196.1 - 0.00016 21.7 1.4 0.36 10.9 0.1 2.3 2 0 0 2 2 2 2 Bd3614-like deaminase MTHFR PF02219.17 CBZ32199.1 - 0.05 12.9 0.1 1.7 7.9 0.0 2.9 4 0 0 4 4 4 0 Methylenetetrahydrofolate reductase MTHFR PF02219.17 CBZ32200.1 - 0.041 13.2 0.1 14 4.9 0.0 3.5 4 0 0 4 4 4 0 Methylenetetrahydrofolate reductase WD40 PF00400.32 CBZ32201.1 - 8.5e-64 210.0 17.7 1.3e-08 35.3 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ32201.1 - 3e-23 81.9 3.3 3.2e-05 24.1 0.0 7.4 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBZ32201.1 - 2.9e-13 49.8 2.2 0.042 13.2 0.1 6.5 3 3 4 7 7 7 5 WD40-like domain Nup160 PF11715.8 CBZ32201.1 - 1.1e-09 37.5 10.1 0.06 12.0 0.1 5.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.11 CBZ32201.1 - 3e-09 37.1 2.3 0.00015 21.7 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBZ32201.1 - 0.0092 15.0 7.1 13 4.6 0.2 5.0 1 1 5 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5570 PF17731.1 CBZ32201.1 - 0.023 14.8 10.5 2.9 8.0 0.0 5.2 1 1 4 5 5 5 0 Family of unknown function (DUF5570) DUF4934 PF16288.5 CBZ32201.1 - 0.069 13.1 0.6 7.4 6.5 0.0 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4934) CEP19 PF14933.6 CBZ32201.1 - 0.12 12.6 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein CBM9_2 PF16011.5 CBZ32201.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate-binding family 9 DFRP_C PF16543.5 CBZ32202.1 - 5.5e-13 49.2 8.0 5.5e-13 49.2 8.0 2.8 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 BetaGal_dom3 PF13363.6 CBZ32204.1 - 0.057 13.0 0.1 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 TPR_2 PF07719.17 CBZ32205.1 - 0.00079 19.4 0.7 4.7 7.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ32205.1 - 0.015 15.5 6.2 0.017 15.4 4.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2153 PF09921.9 CBZ32205.1 - 0.046 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) TPR_10 PF13374.6 CBZ32205.1 - 1.4 8.9 9.2 0.21 11.5 2.6 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 CBZ32206.1 - 5.7e-23 81.6 0.0 1.5e-18 67.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32206.1 - 1.9e-05 24.1 0.0 0.00022 20.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5350 PF17299.2 CBZ32206.1 - 0.21 12.1 3.9 0.21 12.1 1.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5350) A_deaminase PF00962.22 CBZ32207.1 - 6.1e-08 32.3 2.2 0.00011 21.6 0.1 3.2 3 0 0 3 3 3 3 Adenosine/AMP deaminase NTF2 PF02136.20 CBZ32208.1 - 2.5e-26 92.6 0.3 2.7e-26 92.5 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 CBZ32208.1 - 0.00012 22.4 0.0 0.00014 22.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.7 CBZ32208.1 - 0.018 15.7 0.1 0.021 15.5 0.1 1.5 1 1 0 1 1 1 0 Putative lumazine-binding SnoaL_2 PF12680.7 CBZ32208.1 - 0.025 15.2 0.0 0.032 14.9 0.0 1.1 1 0 0 1 1 1 0 SnoaL-like domain Nop16 PF09420.10 CBZ32209.1 - 1.1e-14 55.0 1.7 5.6e-11 42.9 0.3 2.1 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 Histone PF00125.24 CBZ32210.1 - 4.1e-42 143.6 5.4 4.6e-42 143.5 5.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ32210.1 - 1.7e-05 25.0 0.2 1.7e-05 25.0 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBZ32210.1 - 3.2e-05 24.2 0.0 5.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBZ32210.1 - 0.00013 22.0 0.1 0.00022 21.3 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 CBZ32210.1 - 0.0053 16.7 0.1 0.0082 16.1 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 CBZ32210.1 - 0.017 15.2 0.1 0.023 14.8 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Mitochondr_Som1 PF11093.8 CBZ32210.1 - 0.076 13.0 0.1 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 Mitochondrial export protein Som1 FKBP_C PF00254.28 CBZ32212.1 - 6.5e-25 87.3 0.0 9.6e-25 86.7 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2895 PF11444.8 CBZ32212.1 - 0.09 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) IQ PF00612.27 CBZ32213.1 - 5.9 7.0 10.9 0.24 11.3 2.9 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif Ras PF00071.22 CBZ32214.1 - 1.7e-59 200.0 0.1 2e-59 199.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ32214.1 - 2.7e-33 114.8 0.0 4.5e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ32214.1 - 1e-14 54.3 0.0 1.4e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBZ32214.1 - 1.3e-05 25.2 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ32214.1 - 2.3e-05 24.0 0.0 6.8e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ32214.1 - 0.0002 21.3 0.2 0.015 15.2 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase Ploopntkinase3 PF18751.1 CBZ32214.1 - 0.00053 20.0 0.0 0.74 9.7 0.0 2.2 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 SRPRB PF09439.10 CBZ32214.1 - 0.0014 18.1 0.2 0.0024 17.4 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 CBZ32214.1 - 0.0053 17.0 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 CBZ32214.1 - 0.0082 15.5 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 CBZ32214.1 - 0.0096 14.8 0.0 2.5 6.8 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) AAA_7 PF12775.7 CBZ32214.1 - 0.011 15.3 0.2 0.017 14.6 0.2 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 CBZ32214.1 - 0.018 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 CBZ32214.1 - 0.02 14.7 0.0 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CBZ32214.1 - 0.034 13.4 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.17 CBZ32214.1 - 0.039 13.7 0.1 0.16 11.7 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Amidase02_C PF12123.8 CBZ32214.1 - 0.051 13.3 0.0 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AAA_5 PF07728.14 CBZ32214.1 - 0.058 13.4 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ32214.1 - 0.18 12.2 0.0 0.31 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF5510 PF17629.2 CBZ32215.1 - 0.27 11.2 5.2 6.5 6.8 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5510) TMEM119 PF15724.5 CBZ32215.1 - 0.3 11.1 1.4 0.54 10.3 1.4 1.4 1 0 0 1 1 1 0 TMEM119 family IF-2B PF01008.17 CBZ32220.1 - 7.9e-41 140.1 0.0 4.3e-39 134.4 0.0 2.1 2 0 0 2 2 2 2 Initiation factor 2 subunit family FliD_N PF02465.18 CBZ32221.1 - 0.47 11.2 0.1 0.47 11.2 0.1 4.6 4 1 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus YabA PF06156.13 CBZ32221.1 - 9 7.0 15.6 1.2 9.8 0.5 4.2 3 0 0 3 3 3 0 Initiation control protein YabA Histone PF00125.24 CBZ32224.1 - 1.2e-16 61.3 0.7 1.2e-16 61.2 0.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ32224.1 - 0.0002 21.6 0.1 0.00021 21.5 0.1 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CBZ32224.1 - 0.0015 18.8 0.0 0.0016 18.8 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CBZ32224.1 - 0.0069 16.5 0.0 0.0069 16.5 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 CBZ32224.1 - 0.0096 16.0 0.1 0.0096 16.0 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBZ32224.1 - 0.033 14.2 0.0 0.041 13.9 0.0 1.0 1 0 0 1 1 1 0 Bromodomain associated P34-Arc PF04045.14 CBZ32225.1 - 4.3e-05 23.4 0.0 6.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PNP_UDP_1 PF01048.20 CBZ32226.1 - 6.1e-45 153.3 0.3 7.6e-45 153.0 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily CinA PF02464.17 CBZ32226.1 - 0.24 11.0 2.0 4.6 6.8 0.1 2.7 3 0 0 3 3 3 0 Competence-damaged protein Mito_carr PF00153.27 CBZ32227.1 - 1.3e-22 79.6 1.1 3.6e-08 33.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 CBZ32228.1 - 3.1e-10 39.7 0.0 6.1e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CH_2 PF06294.11 CBZ32229.1 - 1.1e-23 83.1 0.0 2.3e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBZ32229.1 - 0.0053 16.6 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain DnaJ PF00226.31 CBZ32230.1 - 1.7e-07 31.3 0.2 3.1e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain KN_motif PF12075.8 CBZ32230.1 - 0.25 11.2 1.5 14 5.6 0.1 2.7 3 0 0 3 3 3 0 KN motif YABBY PF04690.13 CBZ32231.1 - 0.078 13.5 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 YABBY protein Sec8_exocyst PF04048.14 CBZ32232.1 - 7.8 6.4 11.4 1.2 9.0 0.6 3.5 3 1 0 4 4 4 0 Sec8 exocyst complex component specific domain MIF4G PF02854.19 CBZ32233.1 - 1.4e-13 51.0 1.9 1.7e-13 50.7 0.5 1.8 2 0 0 2 2 2 1 MIF4G domain Herpes_BLRF2 PF05812.12 CBZ32233.1 - 0.012 15.7 1.1 0.032 14.4 1.1 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF4041 PF13250.6 CBZ32233.1 - 0.12 12.3 0.1 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Per1 PF04080.13 CBZ32235.1 - 1.6 8.4 4.1 2.1 8.1 4.1 1.1 1 0 0 1 1 1 0 Per1-like family Wzy_C PF04932.15 CBZ32235.1 - 3.6 7.2 8.6 11 5.6 8.5 1.8 1 1 0 1 1 1 0 O-Antigen ligase LsmAD PF06741.13 CBZ32237.1 - 1.7e-18 66.9 1.8 4.4e-18 65.6 1.8 1.8 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 CBZ32237.1 - 1.8e-11 44.0 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain TPR_2 PF07719.17 CBZ32239.1 - 0.79 10.0 2.7 41 4.6 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.6 CBZ32240.1 - 1.4e-15 56.9 10.3 2.4e-15 56.1 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ32240.1 - 4.8e-09 35.9 10.2 7.9e-09 35.2 10.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBZ32240.1 - 4.3e-06 27.0 12.8 8.7e-06 26.0 12.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ32240.1 - 0.0084 15.9 14.1 0.016 15.0 14.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ32240.1 - 0.093 12.7 11.4 0.19 11.7 11.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 CBZ32240.1 - 0.41 10.5 9.1 0.8 9.6 9.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 CBZ32240.1 - 2.1 8.1 9.5 4.7 7.0 9.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger TPH PF13868.6 CBZ32241.1 - 1.5e-64 217.8 156.7 1.5e-64 217.8 156.7 2.0 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain ThiS PF02597.20 CBZ32241.1 - 8.4 7.1 7.8 3.8 8.2 3.2 2.9 2 0 0 2 2 2 0 ThiS family Ras PF00071.22 CBZ32242.1 - 3.2e-54 182.9 0.1 4e-54 182.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ32242.1 - 2.4e-30 105.2 0.0 6.9e-30 103.7 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ32242.1 - 4.7e-11 42.5 0.0 6.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBZ32242.1 - 7.8e-07 28.8 0.1 5.4e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ32242.1 - 4.6e-06 26.7 0.0 1e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBZ32242.1 - 8.6e-05 22.0 0.1 0.00012 21.5 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBZ32242.1 - 0.00064 19.7 0.0 0.032 14.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CBZ32242.1 - 0.0015 19.1 0.0 0.0055 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ32242.1 - 0.0024 18.3 0.1 0.0059 17.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 CBZ32242.1 - 0.0042 16.8 0.0 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CBZ32242.1 - 0.0042 16.9 0.3 0.25 11.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 CBZ32242.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 CBZ32242.1 - 0.018 15.2 0.0 0.04 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain IIGP PF05049.13 CBZ32242.1 - 0.026 13.6 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 CBZ32242.1 - 0.03 14.8 0.1 0.12 12.9 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Gp-FAR-1 PF05823.12 CBZ32242.1 - 0.036 14.4 0.9 0.057 13.8 0.9 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) RNA_helicase PF00910.22 CBZ32242.1 - 0.056 13.8 0.0 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 CBZ32242.1 - 0.066 12.5 0.1 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 CBZ32242.1 - 0.089 13.1 0.0 0.59 10.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 CBZ32242.1 - 0.13 12.3 0.2 3.7 7.6 0.0 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Ras PF00071.22 CBZ32243.1 - 6.1e-45 152.7 0.0 7.2e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ32243.1 - 8.2e-26 90.6 0.0 1.3e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ32243.1 - 8.2e-07 28.6 0.0 9.8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBZ32243.1 - 1.4e-05 24.7 0.0 0.00036 20.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBZ32243.1 - 0.00018 21.0 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ32243.1 - 0.039 14.0 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PrgI PF12666.7 CBZ32244.1 - 0.031 15.0 3.8 0.13 13.0 1.1 2.1 2 0 0 2 2 2 0 PrgI family protein Nterm_IS4 PF13006.7 CBZ32244.1 - 0.043 14.0 0.6 0.16 12.2 0.2 1.9 1 1 1 2 2 2 0 Insertion element 4 transposase N-terminal DUF4131 PF13567.6 CBZ32244.1 - 6.6 6.4 8.2 4.6 6.9 2.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) RIB43A PF05914.12 CBZ32245.1 - 1.6e-75 254.2 66.2 2e-75 253.9 66.2 1.0 1 0 0 1 1 1 1 RIB43A GFD1 PF17331.2 CBZ32245.1 - 1.4 9.2 6.0 0.79 10.0 0.3 3.1 2 0 0 2 2 2 0 GFD1 mRNA transport factor zf-RanBP PF00641.18 CBZ32246.1 - 2e-09 36.6 24.0 0.00075 18.8 5.2 3.6 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others DZR PF12773.7 CBZ32246.1 - 4.5e-07 29.8 17.5 0.00023 21.1 8.8 2.7 1 1 1 2 2 2 2 Double zinc ribbon Ima1_N PF09779.9 CBZ32246.1 - 0.14 13.0 0.2 0.14 13.0 0.2 3.3 3 1 0 3 3 3 0 Ima1 N-terminal domain Atx10homo_assoc PF09759.9 CBZ32250.1 - 2.3e-23 82.1 0.0 4.3e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain DUF1861 PF08950.10 CBZ32254.1 - 5.7e-120 400.0 0.1 6.6e-120 399.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CBZ32255.1 - 2.4e-118 394.7 0.0 2.8e-118 394.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CBZ32256.1 - 2.8e-121 404.3 0.0 3.3e-121 404.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CBZ32257.1 - 7.4e-121 403.0 0.0 8.5e-121 402.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CBZ32258.1 - 2.5e-117 391.3 0.0 2.9e-117 391.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF5565 PF17720.1 CBZ32258.1 - 0.049 12.5 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5565) DUF1861 PF08950.10 CBZ32259.1 - 9.1e-123 409.2 0.0 1.1e-122 409.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) DUF1861 PF08950.10 CBZ32260.1 - 2.1e-121 404.8 0.0 2.4e-121 404.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1861) PHO4 PF01384.20 CBZ32261.1 - 2.7e-110 368.6 19.6 3.2e-110 368.3 19.6 1.1 1 0 0 1 1 1 1 Phosphate transporter family CENP_C_N PF15622.6 CBZ32261.1 - 0.034 13.6 0.2 0.049 13.1 0.2 1.1 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal HECW_N PF16562.5 CBZ32261.1 - 0.17 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 BT1 PF03092.16 CBZ32262.1 - 1.6e-104 350.0 2.9 1.8e-104 349.8 2.9 1.0 1 0 0 1 1 1 1 BT1 family FA_desaturase PF00487.24 CBZ32263.1 - 1.6e-26 93.7 25.3 1.6e-26 93.7 25.3 1.9 1 1 1 2 2 2 1 Fatty acid desaturase CENP-H PF05837.12 CBZ32264.1 - 0.0021 18.5 5.5 0.0021 18.5 5.5 1.7 2 0 0 2 2 2 1 Centromere protein H (CENP-H) DUF3450 PF11932.8 CBZ32264.1 - 0.0027 17.0 2.8 0.0027 17.0 2.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 CBZ32264.1 - 0.01 15.9 14.5 0.029 14.4 4.2 2.2 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Strep_SA_rep PF06696.11 CBZ32264.1 - 0.019 15.0 0.1 0.046 13.7 0.1 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DUF2229 PF09989.9 CBZ32264.1 - 0.073 12.7 0.3 0.081 12.6 0.3 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) GIT_CC PF16559.5 CBZ32264.1 - 0.089 12.7 3.3 0.21 11.5 1.3 2.5 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 CBZ32264.1 - 0.098 12.5 16.0 0.27 11.0 16.0 1.7 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 CBZ32264.1 - 0.14 11.4 15.0 1.4 8.2 14.6 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TRAF_BIRC3_bd PF16673.5 CBZ32264.1 - 0.45 10.3 9.5 0.22 11.4 5.0 2.5 3 1 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain KLRAQ PF10205.9 CBZ32264.1 - 0.48 10.7 7.5 0.12 12.6 3.7 1.9 2 2 0 2 2 2 0 Predicted coiled-coil domain-containing protein TMF_TATA_bd PF12325.8 CBZ32264.1 - 0.55 10.5 12.0 0.054 13.7 6.9 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Shugoshin_N PF07558.11 CBZ32264.1 - 0.86 9.5 8.5 0.19 11.6 2.2 2.5 2 1 1 3 3 3 0 Shugoshin N-terminal coiled-coil region TMF_DNA_bd PF12329.8 CBZ32264.1 - 1.8 8.6 19.4 0.64 10.0 0.3 3.4 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 CBZ32264.1 - 2.1 8.2 8.4 0.82 9.5 4.7 2.2 2 1 1 3 3 3 0 Septum formation initiator YabA PF06156.13 CBZ32264.1 - 2.8 8.6 11.9 9.7 6.9 10.8 2.2 1 1 1 2 2 2 0 Initiation control protein YabA ZapB PF06005.12 CBZ32264.1 - 3.1 8.3 16.7 33 5.0 16.0 2.7 1 1 0 1 1 1 0 Cell division protein ZapB HIP1_clath_bdg PF16515.5 CBZ32264.1 - 4.2 8.0 13.6 14 6.3 11.1 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 COPIIcoated_ERV PF07970.12 CBZ32265.1 - 4.7e-37 128.0 0.0 6.4e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBZ32265.1 - 1.1e-19 70.5 0.0 2e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Hexapep PF00132.24 CBZ32266.1 - 2.7e-12 45.9 4.2 1.1e-05 25.0 0.4 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CBZ32266.1 - 0.0079 15.9 3.3 2.4 8.0 0.4 3.3 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase ABC_tran PF00005.27 CBZ32267.1 - 9.9e-28 97.4 0.0 2.3e-27 96.2 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CBZ32267.1 - 0.0012 18.8 0.8 0.33 10.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ32267.1 - 0.0016 17.9 0.3 0.02 14.3 0.0 2.0 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ32267.1 - 0.0035 17.1 0.1 0.0079 15.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBZ32267.1 - 0.0071 16.3 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CBZ32267.1 - 0.021 15.2 0.1 0.045 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain KDGP_aldolase PF07071.11 CBZ32267.1 - 0.12 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 KDGP aldolase AAA_23 PF13476.6 CBZ32267.1 - 0.17 12.3 0.1 0.38 11.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CBZ32267.1 - 0.27 11.4 1.0 0.77 10.0 0.3 2.0 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 CBZ32267.1 - 1.7 8.9 5.6 1.6 9.0 0.2 3.1 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit SNF2_N PF00176.23 CBZ32268.1 - 3.1e-25 88.6 0.0 5e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HNH PF01844.23 CBZ32268.1 - 7e-09 35.7 0.1 7e-09 35.7 0.1 2.8 2 0 0 2 2 2 1 HNH endonuclease Helicase_C PF00271.31 CBZ32268.1 - 1.2e-05 25.6 0.0 2.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ32268.1 - 0.00012 22.1 0.0 0.00041 20.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HNH_5 PF14279.6 CBZ32268.1 - 0.00064 19.5 0.0 0.00064 19.5 0.0 2.4 2 0 0 2 2 2 1 HNH endonuclease DUF2116 PF09889.9 CBZ32268.1 - 0.025 14.6 0.1 0.11 12.5 0.1 2.1 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Pkinase PF00069.25 CBZ32269.1 - 1.5e-41 142.5 0.0 1.4e-26 93.5 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32269.1 - 4.6e-16 58.9 0.2 1.5e-08 34.2 0.2 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ32269.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family NCD1 PF04904.13 CBZ32269.1 - 0.023 14.7 0.1 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) FTA2 PF13095.6 CBZ32269.1 - 0.026 14.2 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CENP-F_leu_zip PF10473.9 CBZ32270.1 - 0.0073 16.3 4.5 0.0073 16.3 4.5 4.3 3 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rieske PF00355.26 CBZ32270.1 - 0.073 13.0 0.2 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 Rieske [2Fe-2S] domain Pox_A_type_inc PF04508.12 CBZ32270.1 - 0.17 11.8 0.2 0.17 11.8 0.2 3.7 4 1 0 4 4 4 0 Viral A-type inclusion protein repeat BicD PF09730.9 CBZ32270.1 - 0.18 10.2 33.9 0.015 13.8 2.5 2.8 2 1 0 2 2 2 0 Microtubule-associated protein Bicaudal-D MeaB PF03308.16 CBZ32270.1 - 0.82 8.6 5.9 0.28 10.1 0.4 2.4 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SHE3 PF17078.5 CBZ32270.1 - 1 9.0 35.8 4.3 7.0 1.3 4.1 3 1 1 4 4 4 0 SWI5-dependent HO expression protein 3 Metal_resist PF13801.6 CBZ32270.1 - 1.5 9.0 18.3 0.63 10.2 0.2 3.9 1 1 3 4 4 4 0 Heavy-metal resistance HMMR_N PF15905.5 CBZ32270.1 - 4.2 6.8 49.7 0.023 14.2 12.4 4.1 3 1 1 4 4 4 0 Hyaluronan mediated motility receptor N-terminal EzrA PF06160.12 CBZ32270.1 - 4.3 5.4 40.5 1 7.5 14.9 3.5 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA HSP70 PF00012.20 CBZ32270.1 - 4.5 5.3 22.4 41 2.2 22.4 2.0 1 1 0 1 1 1 0 Hsp70 protein DUF4936 PF16290.5 CBZ32270.1 - 7.9 7.2 12.1 0.61 10.8 0.5 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4936) Spc7 PF08317.11 CBZ32270.1 - 7.9 5.3 50.6 5.9 5.7 15.5 3.9 2 1 1 4 4 4 0 Spc7 kinetochore protein GAS PF13851.6 CBZ32270.1 - 8.5 5.7 48.8 1.1 8.6 3.9 4.2 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 CBZ32270.1 - 9.6 5.8 52.7 5.6 6.6 24.4 5.0 3 1 1 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease RRM_1 PF00076.22 CBZ32271.1 - 1.6e-05 24.6 0.1 7.2e-05 22.5 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4636 PF15468.6 CBZ32271.1 - 0.0083 15.9 0.4 0.0083 15.9 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4636) MORN PF02493.20 CBZ32272.1 - 4.9e-26 89.0 32.1 2e-06 27.4 1.1 6.5 6 0 0 6 6 6 6 MORN repeat tRNA-synt_2b PF00587.25 CBZ32273.1 - 5.3e-32 111.2 0.0 1e-31 110.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CBZ32273.1 - 6.7e-14 52.0 4.2 2.5e-12 47.0 4.2 2.3 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.25 CBZ32274.1 - 9.6e-51 172.7 0.0 1.2e-50 172.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32274.1 - 1.7e-26 93.1 0.0 2.4e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ32274.1 - 5e-09 35.9 0.0 1.2e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ32274.1 - 0.00026 21.0 0.6 0.0011 18.9 0.1 2.0 1 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ32274.1 - 0.00055 19.0 0.0 0.00089 18.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CBZ32274.1 - 0.0029 16.7 0.2 0.0045 16.1 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 CBZ32274.1 - 0.0036 16.7 0.1 0.0076 15.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ32274.1 - 0.022 14.4 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family GPHH PF16905.5 CBZ32274.1 - 0.074 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated PAC1 PF16094.5 CBZ32274.1 - 0.087 12.0 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Choline_kinase PF01633.20 CBZ32274.1 - 0.18 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase NIF3 PF01784.18 CBZ32276.1 - 9.1e-69 231.8 0.0 1.1e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) PSP1 PF04468.12 CBZ32277.1 - 3.4e-28 97.8 0.2 5.5e-28 97.1 0.2 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Macoilin PF09726.9 CBZ32278.1 - 0.35 9.4 24.1 0.59 8.6 24.1 1.2 1 0 0 1 1 1 0 Macoilin family DUF3361 PF11841.8 CBZ32279.1 - 1.3 9.0 4.2 1 9.3 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) 3-PAP PF12578.8 CBZ32280.1 - 6.2e-25 87.5 0.5 2.2e-24 85.7 0.5 2.0 1 0 0 1 1 1 1 Myotubularin-associated protein Dzip-like_N PF13815.6 CBZ32280.1 - 0.00036 20.5 0.6 0.00036 20.5 0.6 3.0 2 1 1 3 3 3 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal HAUS-augmin3 PF14932.6 CBZ32280.1 - 0.031 13.9 13.7 0.089 12.4 6.9 2.6 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 DUF812 PF05667.11 CBZ32280.1 - 0.11 11.4 7.7 1 8.2 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Pre-PUA PF17832.1 CBZ32281.1 - 6.4e-20 71.6 0.2 9.9e-20 71.0 0.2 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CBZ32281.1 - 2.9e-15 56.0 1.3 5.3e-15 55.1 1.3 1.4 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CBZ32281.1 - 0.0087 16.3 1.3 0.23 11.8 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) FumaraseC_C PF10415.9 CBZ32281.1 - 0.096 13.1 0.2 0.19 12.2 0.2 1.4 1 0 0 1 1 1 0 Fumarase C C-terminus DEAD PF00270.29 CBZ32282.1 - 1.6e-22 80.1 0.0 2.7e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CBZ32282.1 - 2.2e-06 27.8 0.0 3.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ32282.1 - 2.7e-06 27.7 0.1 2.3e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pyrophosphatase PF00719.19 CBZ32284.1 - 1.1e-45 155.3 0.1 2e-45 154.5 0.1 1.4 1 0 0 1 1 1 1 Inorganic pyrophosphatase EF-hand_7 PF13499.6 CBZ32284.1 - 0.0013 19.1 0.1 0.0091 16.4 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ32284.1 - 0.25 11.0 1.7 3 7.6 0.0 3.1 3 0 0 3 3 3 0 EF hand Pterin_4a PF01329.19 CBZ32285.1 - 1.8e-28 98.5 0.1 2.1e-28 98.3 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Rad51 PF08423.11 CBZ32286.1 - 8.8e-20 71.0 0.0 1.7e-19 70.1 0.0 1.4 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CBZ32286.1 - 3e-08 33.5 1.8 5.8e-08 32.5 1.8 1.5 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CBZ32286.1 - 1e-06 28.3 0.3 5.2e-05 22.7 0.3 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain ATPase PF06745.13 CBZ32286.1 - 1.4e-06 27.9 0.0 5.4e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA PF00004.29 CBZ32286.1 - 2.3e-05 24.8 0.0 8.9e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ32286.1 - 9.7e-05 22.8 0.7 0.0002 21.8 0.7 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ32286.1 - 0.0053 17.0 0.1 0.009 16.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBZ32286.1 - 0.0056 16.9 0.5 0.021 15.0 0.5 2.2 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 CBZ32286.1 - 0.013 14.9 0.1 0.036 13.5 0.0 1.6 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_30 PF13604.6 CBZ32286.1 - 0.027 14.2 0.1 0.076 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBZ32286.1 - 0.04 14.5 0.1 0.078 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain DnaG_DnaB_bind PF08278.11 CBZ32286.1 - 0.093 13.3 1.0 0.19 12.3 1.0 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding PEPCK_ATP PF01293.20 CBZ32286.1 - 0.18 10.4 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase NTPase_1 PF03266.15 CBZ32286.1 - 0.23 11.4 0.2 0.84 9.5 0.2 1.9 1 1 0 1 1 1 0 NTPase Proteasome PF00227.26 CBZ32287.1 - 9e-59 198.2 0.1 1.3e-58 197.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ32287.1 - 1.4e-14 53.4 0.2 2.7e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Styelin PF17562.2 CBZ32287.1 - 0.0096 16.3 3.2 0.049 14.0 1.9 2.2 2 0 0 2 2 2 1 Styelin DUF365 PF04033.12 CBZ32287.1 - 0.043 14.1 0.4 0.096 13.0 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Pkinase PF00069.25 CBZ32288.1 - 3.6e-45 154.4 0.0 1.5e-31 109.8 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32288.1 - 6.9e-28 97.6 0.0 1.7e-21 76.7 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.6 CBZ32288.1 - 1.1e-05 24.9 0.0 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CBZ32288.1 - 9e-05 21.4 0.0 0.0002 20.2 0.0 1.6 1 1 0 1 1 1 1 Fungal protein kinase TPR_10 PF13374.6 CBZ32288.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat APH PF01636.23 CBZ32288.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family PEPCK_ATP PF01293.20 CBZ32289.1 - 0.019 13.6 0.0 0.028 13.1 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase FAD_binding_6 PF00970.24 CBZ32290.1 - 4.9e-09 36.5 0.0 1.9e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBZ32290.1 - 0.0027 18.3 0.0 0.0081 16.8 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain SlyX PF04102.12 CBZ32292.1 - 0.14 12.8 3.2 0.14 12.7 1.5 1.9 2 0 0 2 2 2 0 SlyX Sec20 PF03908.13 CBZ32293.1 - 5.8e-09 35.8 3.3 1.4e-08 34.5 3.3 1.6 1 0 0 1 1 1 1 Sec20 TEX13 PF15186.6 CBZ32293.1 - 0.024 14.3 1.5 0.024 14.3 1.5 2.3 2 1 0 2 2 2 0 Testis-expressed sequence 13 protein family DHR10 PF18595.1 CBZ32293.1 - 0.15 12.1 0.2 0.15 12.1 0.2 2.7 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain FlaC_arch PF05377.11 CBZ32293.1 - 0.71 10.3 3.1 0.72 10.3 0.7 2.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.9 CBZ32294.1 - 5.1 7.5 6.8 1 9.7 0.7 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PIF1 PF05970.14 CBZ32295.1 - 9.3e-30 104.0 0.8 2e-22 79.9 0.8 3.6 3 1 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CBZ32295.1 - 1e-20 74.3 0.1 2.7e-20 72.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBZ32295.1 - 2.2e-05 24.9 2.3 3.5e-05 24.2 0.3 2.4 2 1 0 2 2 2 1 AAA domain DUF853 PF05872.12 CBZ32295.1 - 0.0013 17.4 1.8 0.003 16.2 1.8 1.5 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.6 CBZ32295.1 - 0.0063 16.8 1.2 4 7.7 0.4 2.8 2 0 0 2 2 2 2 AAA domain Herpes_Helicase PF02689.14 CBZ32295.1 - 0.014 13.4 0.1 1.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Helicase UvrD_C_2 PF13538.6 CBZ32295.1 - 0.017 14.9 0.5 0.15 11.9 0.3 2.6 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 CBZ32295.1 - 0.32 10.7 6.6 1.9 8.2 0.1 4.0 3 1 1 4 4 4 0 AAA domain DUF4682 PF15733.5 CBZ32295.1 - 9.1 6.9 7.8 3.9 8.1 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4682) PIF1 PF05970.14 CBZ32296.1 - 2.7e-35 122.2 0.6 9.4e-28 97.4 0.1 3.4 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CBZ32296.1 - 4.7e-18 65.6 0.0 3.1e-17 62.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBZ32296.1 - 5.3e-06 26.8 0.1 2.1e-05 24.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ32296.1 - 0.0015 18.9 0.8 0.01 16.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ32296.1 - 0.0033 17.7 0.7 0.11 12.8 0.7 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CBZ32296.1 - 0.0051 17.2 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ32296.1 - 0.0051 16.8 0.0 0.019 15.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 CBZ32296.1 - 0.0066 16.2 0.1 5.5 6.7 0.0 2.9 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 CBZ32296.1 - 0.01 15.3 1.8 0.011 15.1 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 CBZ32296.1 - 0.013 15.3 0.8 0.057 13.2 0.0 2.4 2 1 0 3 3 3 0 AAA domain UvrD_C_2 PF13538.6 CBZ32296.1 - 0.014 15.2 0.4 0.096 12.5 0.4 2.3 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 CBZ32296.1 - 0.018 13.0 0.3 0.13 10.2 0.0 2.0 2 0 0 2 2 2 0 Helicase PaaA_PaaC PF05138.12 CBZ32296.1 - 0.071 12.3 0.0 0.27 10.3 0.0 1.9 2 0 0 2 2 2 0 Phenylacetic acid catabolic protein PhoH PF02562.16 CBZ32296.1 - 0.085 12.3 0.1 0.22 11.0 0.1 1.7 1 0 0 1 1 1 0 PhoH-like protein DinB_2 PF12867.7 CBZ32296.1 - 0.088 13.3 0.1 3.9 8.0 0.1 2.8 2 0 0 2 2 2 0 DinB superfamily NACHT PF05729.12 CBZ32296.1 - 0.15 12.0 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CBZ32296.1 - 0.41 10.6 1.5 1.8 8.4 0.2 2.2 2 0 0 2 2 2 0 NTPase 14-3-3 PF00244.20 CBZ32298.1 - 1.7e-83 279.5 2.1 2e-83 279.3 2.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_8 PF13181.6 CBZ32298.1 - 4.9 7.6 6.4 25 5.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat OPA3 PF07047.12 CBZ32299.1 - 5.1e-19 68.3 4.5 4.1e-18 65.3 4.5 2.1 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF5446 PF17522.2 CBZ32299.1 - 0.03 14.5 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5446) Herpes_UL25 PF01499.16 CBZ32299.1 - 0.48 8.9 3.4 0.62 8.5 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL25 family LrgB PF04172.16 CBZ32299.1 - 1.2 8.7 8.0 0.036 13.6 0.8 1.9 1 1 1 2 2 2 0 LrgB-like family Med3 PF11593.8 CBZ32299.1 - 2.2 7.4 15.5 3.2 6.8 15.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CEP63 PF17045.5 CBZ32300.1 - 8.6 6.2 54.8 0.88 9.4 25.4 3.7 3 1 0 3 3 3 0 Centrosomal protein of 63 kDa DUF2779 PF11074.8 CBZ32301.1 - 1.7e-39 135.2 0.0 2.9e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) DNA_pol_B_2 PF03175.13 CBZ32301.1 - 0.097 11.5 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral TTL PF03133.15 CBZ32303.1 - 2.1e-68 230.6 0.1 3.2e-68 230.0 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ32303.1 - 4.4e-08 32.7 0.1 0.00022 20.6 0.0 3.3 2 1 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBZ32303.1 - 6.7e-05 22.3 0.0 0.027 13.7 0.0 2.5 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 CBZ32303.1 - 0.013 15.6 0.0 0.037 14.1 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain BOP1NT PF08145.12 CBZ32304.1 - 4.1e-79 266.2 8.5 6.9e-79 265.4 8.5 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CBZ32304.1 - 1.5e-17 63.6 3.3 1.5e-07 32.0 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ32304.1 - 3.9e-07 30.3 0.0 0.0014 18.9 0.0 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ32304.1 - 0.022 13.7 0.0 1 8.3 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RCC1 PF00415.18 CBZ32305.1 - 4e-26 91.4 19.1 7.2e-07 29.7 0.2 8.5 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ32305.1 - 8e-12 44.6 21.4 4.5e-07 29.5 0.4 6.1 5 1 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat TLP-20 PF06088.11 CBZ32306.1 - 0.17 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) LRR_4 PF12799.7 CBZ32307.1 - 1.6e-13 50.6 18.6 3.7e-05 24.0 0.2 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ32307.1 - 3e-09 36.5 23.0 0.00028 20.6 3.4 4.1 3 1 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 CBZ32307.1 - 4e-07 29.6 14.4 0.19 11.8 0.7 5.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 CBZ32307.1 - 0.00024 20.7 3.4 0.0047 16.4 0.7 2.9 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 CBZ32307.1 - 0.014 15.9 19.7 12 6.9 0.1 7.2 7 0 0 7 7 7 0 Leucine Rich Repeat DNA_ligase_OB_2 PF14743.6 CBZ32308.1 - 0.063 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 CBZ32308.1 - 0.13 11.9 0.0 12 5.5 0.0 2.9 3 0 0 3 3 3 0 ATP dependent DNA ligase domain PUF PF00806.19 CBZ32310.1 - 1.9e-09 36.7 0.0 1.8 8.4 0.0 5.8 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat CPL PF08144.11 CBZ32310.1 - 0.015 15.6 4.9 0.36 11.2 0.1 4.7 4 2 3 7 7 7 0 CPL (NUC119) domain LEA_3 PF03242.13 CBZ32310.1 - 3.1 8.6 8.3 2.6 8.8 2.2 2.9 2 0 0 2 2 2 0 Late embryogenesis abundant protein ArsC PF03960.15 CBZ32311.1 - 0.17 12.0 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 ArsC family Cyt-b5 PF00173.28 CBZ32312.1 - 9.4e-20 70.5 0.0 1.3e-19 70.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tex_N PF09371.10 CBZ32314.1 - 5.2e-39 133.8 0.8 1.3e-38 132.5 0.0 2.1 3 0 0 3 3 3 1 Tex-like protein N-terminal domain Tex_YqgF PF16921.5 CBZ32314.1 - 1.3e-32 112.9 0.1 3.3e-32 111.6 0.1 1.8 1 0 0 1 1 1 1 Tex protein YqgF-like domain HHH_9 PF17674.1 CBZ32314.1 - 2.7e-11 44.2 0.2 5.3e-09 36.9 0.2 3.4 1 1 0 1 1 1 1 HHH domain HHH_3 PF12836.7 CBZ32314.1 - 7.1e-10 39.0 0.1 1.5e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 CBZ32314.1 - 4.2e-06 26.6 0.0 8.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 CBZ32314.1 - 0.00019 21.7 0.0 0.00057 20.2 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.23 CBZ32314.1 - 0.021 15.2 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 S1 RNA binding domain Nucleoside_tran PF01733.18 CBZ32315.1 - 8.8e-35 120.6 5.8 2.5e-25 89.5 0.3 2.4 2 0 0 2 2 2 2 Nucleoside transporter DUF563 PF04577.14 CBZ32316.1 - 2e-11 44.4 0.0 5.7e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF563) AA_permease_2 PF13520.6 CBZ32318.1 - 2.5e-19 69.4 36.9 3.8e-19 68.8 36.9 1.2 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 CBZ32319.1 - 2.1e-31 109.3 0.0 5.4e-31 107.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32319.1 - 6.7e-14 51.8 0.0 2.3e-11 43.5 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ32319.1 - 0.0014 17.5 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CBZ32319.1 - 0.006 15.6 0.2 0.0088 15.1 0.2 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CBZ32319.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family TPR_1 PF00515.28 CBZ32321.1 - 1.8e-17 62.3 16.8 1.1e-05 25.1 1.2 6.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ32321.1 - 1.1e-16 59.5 14.9 2.8e-06 27.0 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ32321.1 - 4e-14 52.0 8.2 1.3e-05 24.8 0.0 5.3 4 1 1 5 5 5 3 TPR repeat TPR_7 PF13176.6 CBZ32321.1 - 2.3e-09 36.6 1.1 0.00086 19.2 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ32321.1 - 3e-08 33.5 9.1 0.24 11.9 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ32321.1 - 7.4e-08 32.6 12.4 0.001 19.3 0.2 5.2 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ32321.1 - 2.1e-07 31.5 5.5 0.057 14.1 0.4 5.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ32321.1 - 1.4e-06 28.7 10.0 0.21 12.1 0.1 4.9 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ32321.1 - 2.8e-06 27.1 19.8 0.003 17.7 1.1 6.7 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ32321.1 - 6.5e-06 26.5 7.2 0.07 13.8 0.1 5.2 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ32321.1 - 0.00086 19.9 14.3 0.15 13.0 0.0 5.1 5 1 1 6 6 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBZ32321.1 - 0.0012 18.1 0.5 0.014 14.6 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3808 PF10300.9 CBZ32321.1 - 0.0055 15.5 0.3 0.015 14.0 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_9 PF13371.6 CBZ32321.1 - 0.0067 16.6 0.6 1.7 8.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ32321.1 - 0.0094 15.8 1.3 1.2 9.1 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ32321.1 - 0.027 14.6 0.1 0.64 10.1 0.0 3.0 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CBZ32321.1 - 0.07 13.4 6.6 0.18 12.0 0.8 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 FAT PF02259.23 CBZ32321.1 - 0.078 12.2 2.8 0.038 13.2 0.2 1.8 2 1 1 3 3 3 0 FAT domain MIT PF04212.18 CBZ32321.1 - 0.44 10.7 16.8 0.57 10.3 0.1 4.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 CBZ32321.1 - 0.53 10.0 3.1 2.3 7.9 0.2 3.2 4 1 1 5 5 5 0 26S proteasome subunit RPN7 Pox_MCEL PF03291.16 CBZ32322.1 - 5.8e-15 55.2 0.0 9.8e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CBZ32322.1 - 4.5e-09 36.9 0.0 3e-07 31.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ32322.1 - 1.1e-05 25.9 0.0 0.00014 22.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ32322.1 - 1.6e-05 25.6 0.0 8.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain NSP16 PF06460.12 CBZ32322.1 - 0.00015 21.0 0.1 0.00024 20.3 0.1 1.2 1 0 0 1 1 1 1 Coronavirus NSP16 Methyltransf_23 PF13489.6 CBZ32322.1 - 0.0032 17.3 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PAM2 PF07145.15 CBZ32322.1 - 0.027 14.2 0.8 0.084 12.6 0.8 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region TPMT PF05724.11 CBZ32322.1 - 0.052 13.2 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) PHF5 PF03660.14 CBZ32322.1 - 0.096 12.9 1.2 0.29 11.3 1.2 1.7 1 0 0 1 1 1 0 PHF5-like protein MTS PF05175.14 CBZ32322.1 - 0.17 11.4 0.0 0.5 9.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain zf-CHY PF05495.12 CBZ32322.1 - 0.5 10.9 6.7 1.3 9.6 6.7 1.6 1 0 0 1 1 1 0 CHY zinc finger Carboxyl_trans PF01039.22 CBZ32323.1 - 5.1e-141 470.7 0.0 7.6e-141 470.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBZ32323.1 - 2.1e-06 27.4 0.1 0.055 12.9 0.0 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 CBZ32323.1 - 0.33 10.2 6.6 1.7 7.9 0.1 3.3 4 0 0 4 4 4 0 Enoyl-CoA hydratase/isomerase Peptidase_M17 PF00883.21 CBZ32326.1 - 2.9e-85 286.3 0.3 3.3e-85 286.1 0.3 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17 PF00883.21 CBZ32327.1 - 2.4e-34 119.0 0.4 3.8e-34 118.4 0.4 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 CBZ32327.1 - 8.7e-30 103.5 2.3 8.7e-30 103.5 2.3 2.4 4 0 0 4 4 4 1 M17 aminopeptidase N-terminal domain 2 MFS_1 PF07690.16 CBZ32329.1 - 8.7e-24 84.1 25.2 1.1e-19 70.7 14.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ32329.1 - 2.5e-09 37.0 8.8 2.5e-09 37.0 8.8 2.3 2 1 0 2 2 2 1 Nodulin-like DUF996 PF06195.13 CBZ32329.1 - 0.17 12.2 0.1 0.17 12.2 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF996) Nodulin-like PF06813.13 CBZ32330.1 - 5e-10 39.3 12.1 5e-10 39.3 12.1 2.3 2 1 0 2 2 2 1 Nodulin-like MotA_ExbB PF01618.16 CBZ32330.1 - 0.19 11.5 0.5 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Nodulin-like PF06813.13 CBZ32331.1 - 2e-06 27.5 22.9 2e-06 27.5 22.9 3.4 2 2 1 3 3 3 1 Nodulin-like MFS_1 PF07690.16 CBZ32332.1 - 0.00054 19.0 5.2 0.00055 19.0 5.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_4 PF13637.6 CBZ32333.1 - 6.1e-25 87.3 1.3 4e-07 30.5 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ32333.1 - 2.9e-23 82.2 0.5 3.8e-10 40.2 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 CBZ32333.1 - 6.1e-16 58.1 1.5 0.00019 21.7 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CBZ32333.1 - 1.8e-15 56.8 2.8 0.0015 18.8 0.0 4.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ32333.1 - 1.1e-14 53.1 1.2 0.0083 16.6 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat DUF4829 PF16111.5 CBZ32333.1 - 0.063 14.1 0.0 0.12 13.2 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4829) DpaA_N PF16924.5 CBZ32333.1 - 0.14 12.3 0.8 1.9 8.6 0.1 2.6 2 1 1 3 3 3 0 Dipicolinate synthase subunit A N-terminal domain ArsA_ATPase PF02374.15 CBZ32334.1 - 2.6e-89 299.4 0.1 3.6e-49 167.6 0.0 2.2 2 0 0 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 CBZ32334.1 - 3.1e-07 30.5 0.1 2.4e-06 27.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 CBZ32334.1 - 5.2e-07 29.8 0.0 3.4e-05 23.9 1.2 2.3 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 CBZ32334.1 - 0.006 16.1 0.1 0.031 13.7 0.1 2.0 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 CBZ32334.1 - 0.026 14.1 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CBZ32334.1 - 0.054 13.1 0.4 2.7 7.6 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 CBZ32334.1 - 0.22 11.0 0.0 0.83 9.0 0.0 1.9 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 CBZ32334.1 - 0.25 10.5 0.1 0.41 9.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain Peptidase_C11 PF03415.14 CBZ32336.1 - 9.9e-07 28.5 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Clostripain family T4bSS_IcmS PF12608.8 CBZ32337.1 - 0.11 12.8 0.7 0.35 11.2 0.0 2.2 2 0 0 2 2 2 0 Type IVb secretion, IcmS, effector-recruitment DUF1541 PF07563.11 CBZ32338.1 - 0.033 14.1 1.6 0.23 11.4 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1541) MIT PF04212.18 CBZ32339.1 - 0.12 12.5 1.3 0.36 10.9 1.3 1.9 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain Ribosomal_S21e PF01249.18 CBZ32340.1 - 2.8e-33 113.9 0.1 3e-33 113.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Ribosomal_S21e PF01249.18 CBZ32341.1 - 1.6e-32 111.4 0.6 2.4e-32 110.9 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S21e COX6B PF02297.17 CBZ32342.1 - 0.00059 20.0 9.4 0.15 12.3 1.6 2.9 1 1 2 3 3 3 3 Cytochrome oxidase c subunit VIb CX9C PF16860.5 CBZ32342.1 - 1.1 9.3 8.7 13 5.9 0.0 3.4 3 1 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Activin_recp PF01064.23 CBZ32342.1 - 3.2 8.9 8.2 8.7 7.5 8.2 1.9 1 1 0 1 1 1 0 Activin types I and II receptor domain EF-hand_6 PF13405.6 CBZ32344.1 - 1.1e-13 49.9 0.0 0.11 12.5 0.0 7.2 8 0 0 8 8 8 4 EF-hand domain EF-hand_7 PF13499.6 CBZ32344.1 - 6e-11 42.6 0.0 0.34 11.4 0.0 5.7 6 0 0 6 6 6 4 EF-hand domain pair EF-hand_1 PF00036.32 CBZ32344.1 - 0.00011 21.4 0.0 3.9 7.2 0.0 5.2 6 0 0 6 6 6 2 EF hand EF-hand_11 PF08976.11 CBZ32344.1 - 0.008 17.0 0.1 6.3 7.7 0.0 4.2 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 CBZ32344.1 - 0.027 14.3 0.0 37 4.3 0.0 4.8 5 0 0 5 5 5 0 EF-hand domain pair DUF3552 PF12072.8 CBZ32345.1 - 0.00014 21.3 12.5 0.0002 20.9 12.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Jnk-SapK_ap_N PF09744.9 CBZ32345.1 - 0.065 13.5 12.9 0.11 12.7 12.9 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 CBZ32345.1 - 0.32 11.5 14.6 0.55 10.8 14.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 CBZ32345.1 - 2.7 5.8 9.8 3.4 5.5 9.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Hamartin PF04388.12 CBZ32345.1 - 4 6.0 14.1 4.9 5.7 14.1 1.1 1 0 0 1 1 1 0 Hamartin protein ALMT PF11744.8 CBZ32345.1 - 4.2 6.1 6.8 5.2 5.8 6.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3807 PF12720.7 CBZ32345.1 - 6.9 6.9 15.1 12 6.1 15.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) OmpH PF03938.14 CBZ32345.1 - 7.5 6.9 25.4 15 5.9 25.4 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Neur_chan_memb PF02932.16 CBZ32345.1 - 7.8 6.5 11.3 12 5.8 11.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DLIC PF05783.11 CBZ32345.1 - 8 5.2 7.4 11 4.7 7.4 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) LRS4 PF10422.9 CBZ32346.1 - 0.011 15.3 7.0 0.04 13.5 7.0 2.0 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 AAA_13 PF13166.6 CBZ32346.1 - 0.057 12.1 9.1 0.085 11.5 9.1 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 CBZ32346.1 - 0.12 11.3 11.0 0.22 10.4 11.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Borrelia_P83 PF05262.11 CBZ32346.1 - 0.51 8.8 8.8 0.73 8.3 8.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein LCD1 PF09798.9 CBZ32346.1 - 0.65 8.4 6.5 0.9 8.0 6.5 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein FapA PF03961.13 CBZ32346.1 - 1.1 7.8 7.0 1.6 7.3 7.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMCO5 PF14992.6 CBZ32346.1 - 2 8.0 12.2 3 7.4 12.2 1.2 1 0 0 1 1 1 0 TMCO5 family DUF2203 PF09969.9 CBZ32346.1 - 3.4 8.4 8.0 9.4 7.0 7.4 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.19 CBZ32346.1 - 3.4 5.4 5.8 5.9 4.7 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-H PF05837.12 CBZ32346.1 - 3.7 8.0 15.7 19 5.7 15.7 2.1 1 1 0 1 1 1 0 Centromere protein H (CENP-H) TMF_DNA_bd PF12329.8 CBZ32346.1 - 8.5 6.5 22.1 0.18 11.8 11.6 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Abhydrolase_1 PF00561.20 CBZ32347.1 - 3.9e-05 23.4 0.0 6.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ32347.1 - 0.009 15.3 0.0 0.082 12.2 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ32347.1 - 0.0097 16.5 0.1 0.023 15.3 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CBZ32347.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 CBZ32348.1 - 1.4e-05 24.5 0.0 2.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ32348.1 - 0.014 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold HEAT PF02985.22 CBZ32349.1 - 0.018 15.3 16.4 6.3 7.4 0.0 6.8 7 0 0 7 7 7 0 HEAT repeat ImpA_N PF06812.12 CBZ32349.1 - 1.6 8.8 7.4 1.6 8.9 0.1 4.2 5 0 0 5 5 5 0 ImpA, N-terminal, type VI secretion system Kinesin PF00225.23 CBZ32350.1 - 0.0058 15.6 0.1 0.011 14.7 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain YscO-like PF16789.5 CBZ32350.1 - 5.3 7.0 11.3 0.41 10.7 3.7 2.4 2 0 0 2 2 2 0 YscO-like protein Exonuc_VII_L PF02601.15 CBZ32350.1 - 8.2 5.9 11.6 12 5.4 4.7 2.8 2 1 0 2 2 2 0 Exonuclease VII, large subunit DUF772 PF05598.11 CBZ32351.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.6 1 1 0 1 1 1 0 Transposase domain (DUF772) LRR_6 PF13516.6 CBZ32352.1 - 3.4e-23 79.7 20.0 0.0084 16.1 0.1 11.9 12 0 0 12 12 12 7 Leucine Rich repeat LRR_4 PF12799.7 CBZ32352.1 - 3.4e-13 49.6 10.6 0.0014 18.9 0.4 8.3 10 0 0 10 10 10 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ32352.1 - 1.7e-07 30.8 7.1 9.3 7.2 0.1 9.4 11 0 0 11 11 11 1 Leucine Rich Repeat LRR_8 PF13855.6 CBZ32352.1 - 2.7e-07 30.2 25.3 0.0018 18.0 3.1 7.9 10 1 0 10 10 10 3 Leucine rich repeat FAD_binding_1 PF00667.20 CBZ32352.1 - 0.085 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Ribosomal_L24e PF01246.20 CBZ32353.1 - 1.9e-32 111.3 3.6 1.9e-32 111.3 3.6 2.5 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.14 CBZ32353.1 - 0.004 17.1 6.5 0.0069 16.3 6.5 1.3 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif zf-FLZ PF04570.14 CBZ32353.1 - 0.37 10.3 4.6 0.91 9.0 4.6 1.6 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 AAA PF00004.29 CBZ32354.1 - 9.7e-40 136.0 0.0 3.6e-39 134.2 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ32354.1 - 1.9e-10 40.4 0.0 1.9e-10 40.4 0.0 2.5 3 0 0 3 3 3 1 AAA+ lid domain AAA_16 PF13191.6 CBZ32354.1 - 2.8e-05 24.5 1.4 0.00057 20.3 1.4 3.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 CBZ32354.1 - 0.00014 22.1 0.0 0.0003 21.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CBZ32354.1 - 0.00081 19.7 0.0 0.0024 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBZ32354.1 - 0.005 16.8 0.2 0.062 13.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBZ32354.1 - 0.014 15.5 1.1 0.056 13.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBZ32354.1 - 0.027 15.0 0.0 0.081 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBZ32354.1 - 0.038 13.7 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 CBZ32354.1 - 0.065 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CBZ32354.1 - 0.068 12.5 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CBZ32354.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GT-D PF08759.11 CBZ32354.1 - 0.091 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Bromodomain PF00439.25 CBZ32354.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Bromodomain MMR_HSR1 PF01926.23 CBZ32354.1 - 0.16 12.0 0.0 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase PUB PF09409.10 CBZ32355.1 - 3.7e-10 39.6 0.0 7.2e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 PUB domain SHOCT PF09851.9 CBZ32355.1 - 0.00058 19.5 0.7 0.00058 19.5 0.7 2.1 2 0 0 2 2 2 1 Short C-terminal domain Chorion_2 PF03964.15 CBZ32355.1 - 0.025 15.4 5.2 0.025 15.4 5.2 4.7 4 1 1 5 5 5 0 Chorion family 2 hnRNP_Q_AcD PF18360.1 CBZ32355.1 - 0.1 12.5 0.1 0.5 10.4 0.1 2.1 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF1682 PF07946.14 CBZ32355.1 - 0.27 10.4 6.4 0.45 9.7 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Surp PF01805.20 CBZ32356.1 - 0.019 15.0 1.9 0.034 14.1 0.3 2.3 2 0 0 2 2 2 0 Surp module Baculo_gp64 PF03273.13 CBZ32357.1 - 0.037 12.9 0.2 0.058 12.2 0.2 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Ribosomal_60s PF00428.19 CBZ32358.1 - 0.051 14.2 1.6 0.051 14.2 1.6 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein SPT6_acidic PF14632.6 CBZ32358.1 - 0.25 12.0 0.2 0.25 12.0 0.2 2.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Ribosomal_S7 PF00177.21 CBZ32359.1 - 0.0027 17.3 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S7 PF00177.21 CBZ32360.1 - 1e-05 25.3 0.0 1.1e-05 25.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF89 PF01937.19 CBZ32360.1 - 0.028 13.4 0.0 0.029 13.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF89 zf-HIT PF04438.16 CBZ32361.1 - 9.4e-08 31.8 6.5 1.9e-07 30.8 6.5 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 CBZ32361.1 - 0.015 15.4 3.9 0.034 14.2 3.9 1.6 1 0 0 1 1 1 0 MYND finger zf-FPG_IleRS PF06827.14 CBZ32361.1 - 0.96 9.4 4.7 2.2 8.2 0.2 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Adaptin_N PF01602.20 CBZ32362.1 - 6e-79 266.0 0.0 7.9e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBZ32362.1 - 1.3e-15 57.8 0.6 9.9e-15 55.0 0.0 2.8 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ32362.1 - 3.8e-07 30.4 3.4 0.0028 18.0 0.1 4.8 3 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 CBZ32362.1 - 0.11 12.8 1.6 30 5.2 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 CBZ32362.1 - 0.11 13.0 13.8 1.5 9.4 0.0 6.3 6 1 1 7 7 7 0 HEAT-like repeat DUF3137 PF11335.8 CBZ32362.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) PEP-utilizers_C PF02896.18 CBZ32363.1 - 8.7e-92 307.3 0.0 1.3e-91 306.8 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 CBZ32363.1 - 1.4e-74 251.3 0.0 2.3e-72 244.1 0.0 2.1 1 1 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 CBZ32363.1 - 5.7e-28 96.5 0.6 1.4e-27 95.2 0.6 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain HTH_AsnC-type PF13404.6 CBZ32363.1 - 0.0026 17.6 0.2 0.0078 16.0 0.2 1.9 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_24 PF13412.6 CBZ32363.1 - 0.004 16.7 0.0 0.009 15.6 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding Sigma70_r4 PF04545.16 CBZ32363.1 - 0.0074 15.8 0.0 0.025 14.1 0.0 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 DUF3788 PF12663.7 CBZ32363.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) HTH_11 PF08279.12 CBZ32363.1 - 0.072 13.1 0.0 0.25 11.3 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_28 PF13518.6 CBZ32363.1 - 0.087 13.0 0.0 24 5.1 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Ovate PF04844.13 CBZ32363.1 - 0.18 11.8 0.0 17 5.5 0.0 2.6 2 0 0 2 2 2 0 Transcriptional repressor, ovate YdaS_antitoxin PF15943.5 CBZ32363.1 - 0.18 11.7 0.7 9.7 6.1 0.1 3.2 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Exo_endo_phos PF03372.23 CBZ32364.1 - 0.018 14.6 0.0 0.075 12.5 0.0 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family SAT PF16073.5 CBZ32365.1 - 3.7e-10 39.9 0.1 3.7e-10 39.9 0.1 2.3 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis HydF_dimer PF18128.1 CBZ32366.1 - 0.12 12.5 0.3 0.29 11.2 0.1 1.7 2 0 0 2 2 2 0 Hydrogen maturase F dimerization domain SecY PF00344.20 CBZ32368.1 - 1e-62 212.2 6.9 1.3e-62 211.9 6.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CBZ32368.1 - 1e-14 54.0 0.0 2.4e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p TMEM237 PF15383.6 CBZ32368.1 - 0.0069 15.5 0.2 0.013 14.6 0.2 1.4 1 0 0 1 1 1 1 Transmembrane protein 237 DHHC PF01529.20 CBZ32371.1 - 2.5e-26 92.3 11.3 2.5e-26 92.3 11.3 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase MASE5 PF17178.4 CBZ32371.1 - 0.031 14.1 0.7 0.031 14.1 0.7 1.7 2 0 0 2 2 2 0 Membrane-associated sensor DUF373 PF04123.13 CBZ32371.1 - 0.071 12.5 0.8 0.16 11.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF2614 PF11023.8 CBZ32371.1 - 6 7.0 7.1 5.1 7.2 3.6 2.2 2 0 0 2 2 2 0 Zinc-ribbon containing domain DHHC PF01529.20 CBZ32372.1 - 3.3e-24 85.5 13.7 3.3e-24 85.5 13.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase p450 PF00067.22 CBZ32373.1 - 5.2e-66 223.3 0.0 6.4e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L28e PF01778.17 CBZ32374.1 - 1.6e-18 67.5 1.6 2e-18 67.2 0.1 1.7 1 1 1 2 2 2 1 Ribosomal L28e protein family bPH_6 PF10756.9 CBZ32374.1 - 0.0069 16.5 0.4 0.0097 16.0 0.4 1.3 1 0 0 1 1 1 1 Bacterial PH domain Ribosomal_L28e PF01778.17 CBZ32376.1 - 2.9e-06 28.0 0.5 3.1e-06 27.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family WD40 PF00400.32 CBZ32377.1 - 1.1e-09 38.8 9.4 0.015 16.2 0.1 5.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Sec16_C PF12931.7 CBZ32377.1 - 9.5e-06 25.5 0.0 7.9e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Sel1 PF08238.12 CBZ32377.1 - 0.041 14.6 0.1 0.1 13.3 0.1 1.7 1 0 0 1 1 1 0 Sel1 repeat TPR_12 PF13424.6 CBZ32377.1 - 0.077 13.3 1.8 1.2 9.5 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ32377.1 - 0.19 11.9 7.4 3.1 8.1 0.3 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ32377.1 - 0.2 11.5 0.5 3.3 7.7 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 CBZ32378.1 - 1.1e-09 38.8 9.4 0.015 16.2 0.1 5.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Sec16_C PF12931.7 CBZ32378.1 - 9.5e-06 25.5 0.0 7.9e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Sel1 PF08238.12 CBZ32378.1 - 0.041 14.6 0.1 0.1 13.3 0.1 1.7 1 0 0 1 1 1 0 Sel1 repeat TPR_12 PF13424.6 CBZ32378.1 - 0.077 13.3 1.8 1.2 9.5 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ32378.1 - 0.19 11.9 7.4 3.1 8.1 0.3 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ32378.1 - 0.2 11.5 0.5 3.3 7.7 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 CBZ32379.1 - 1.5e-41 142.1 0.0 3.5e-41 140.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ32379.1 - 3.2e-29 101.5 0.1 9.9e-29 99.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ32379.1 - 0.00075 19.8 0.3 0.0046 17.3 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ32379.1 - 0.0019 18.2 0.0 0.012 15.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CBZ32379.1 - 0.047 12.9 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit 60KD_IMP PF02096.20 CBZ32380.1 - 5e-10 39.5 0.2 8.9e-10 38.7 0.2 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Nefa_Nip30_N PF10187.9 CBZ32380.1 - 0.072 13.5 0.2 0.62 10.5 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Ribosomal_S8 PF00410.19 CBZ32381.1 - 5.4e-21 74.9 0.0 6.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Solute_trans_a PF03619.16 CBZ32382.1 - 3.6e-72 243.1 18.9 4.7e-72 242.7 18.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Prok-RING_2 PF14445.6 CBZ32382.1 - 0.025 14.7 0.8 0.083 13.1 0.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 Glycos_transf_2 PF00535.26 CBZ32382.1 - 0.062 13.1 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Skp1 PF01466.19 CBZ32383.1 - 1.3e-26 92.4 2.2 2.1e-26 91.7 2.2 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CBZ32383.1 - 9.3e-13 48.2 0.0 9.7e-12 44.9 0.0 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain ABC2_membrane_3 PF12698.7 CBZ32384.1 - 3.3e-59 200.8 61.8 1.1e-41 143.1 20.9 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ32384.1 - 1.3e-52 178.0 0.0 2.5e-26 92.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ32384.1 - 1.7e-16 60.9 0.4 3e-07 30.6 0.0 4.6 5 0 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ32384.1 - 3e-05 24.6 0.9 0.37 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 CBZ32384.1 - 0.00061 19.5 1.0 1 9.0 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 CBZ32384.1 - 0.0023 17.9 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 CBZ32384.1 - 0.0029 16.9 0.2 5.5 6.2 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 CBZ32384.1 - 0.0033 17.2 0.3 0.43 10.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBZ32384.1 - 0.0059 16.3 0.3 2 8.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 CBZ32384.1 - 0.0076 16.5 0.0 4.9 7.5 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 CBZ32384.1 - 0.01 15.3 0.0 43 3.4 0.1 3.4 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 CBZ32384.1 - 0.011 16.4 0.0 1.5 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_15 PF13175.6 CBZ32384.1 - 0.015 15.1 0.0 6.2 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_16 PF13191.6 CBZ32384.1 - 0.085 13.2 0.1 14 6.0 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain AAA PF00004.29 CBZ32384.1 - 0.13 12.7 0.2 3.7 8.0 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 CBZ32384.1 - 0.25 11.4 0.3 19 5.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase MukB PF04310.12 CBZ32384.1 - 0.47 10.2 1.7 9.3 6.0 0.3 2.4 2 0 0 2 2 2 0 MukB N-terminal DUF87 PF01935.17 CBZ32384.1 - 1.3 9.1 2.4 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_28 PF13521.6 CBZ32384.1 - 3.4 7.9 4.7 13 6.0 0.4 3.0 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CBZ32386.1 - 2e-28 99.6 0.0 3.9e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 CBZ32386.1 - 3.3e-19 69.2 19.6 4.9e-18 65.4 17.2 2.3 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 CBZ32386.1 - 5.2e-08 33.1 0.0 5.8e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ32386.1 - 0.00035 20.1 0.0 0.004 16.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBZ32386.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 CBZ32386.1 - 0.059 13.9 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 CBZ32386.1 - 0.1 12.8 2.3 0.46 10.8 0.0 3.1 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CBZ32386.1 - 0.13 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 CBZ32386.1 - 0.17 11.6 0.0 1 9.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane PF01061.24 CBZ32386.1 - 1.6 8.1 27.1 0.95 8.8 17.7 3.4 3 0 0 3 3 3 0 ABC-2 type transporter ABC2_membrane_2 PF12679.7 CBZ32386.1 - 4.3 6.5 13.7 9.9 5.3 13.7 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 CBZ32387.1 - 4.3e-69 233.3 62.5 3.7e-49 167.7 17.7 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ32387.1 - 1.2e-50 171.6 0.0 1.5e-24 87.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ32387.1 - 1.4e-17 64.5 0.9 6.7e-07 29.4 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ32387.1 - 7.1e-06 25.6 0.0 1.1 8.6 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CBZ32387.1 - 3.6e-05 24.3 0.3 0.16 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CBZ32387.1 - 7.3e-05 22.6 0.0 1.7 8.3 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.6 CBZ32387.1 - 0.00013 22.1 0.0 0.32 11.2 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 CBZ32387.1 - 0.00027 20.9 0.0 0.077 12.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 CBZ32387.1 - 0.00076 19.3 0.1 0.089 12.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CBZ32387.1 - 0.00083 19.0 0.3 0.26 10.9 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CBZ32387.1 - 0.0011 18.3 0.1 12 5.1 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin AAA_29 PF13555.6 CBZ32387.1 - 0.0013 18.5 0.1 0.5 10.2 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF4162 PF13732.6 CBZ32387.1 - 0.004 17.8 0.0 2.1 9.1 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 CBZ32387.1 - 0.019 15.4 0.0 2.6 8.4 0.0 3.0 3 0 0 3 3 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 CBZ32387.1 - 0.1 12.7 0.0 15 5.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arf PF00025.21 CBZ32387.1 - 0.11 12.0 0.1 5.1 6.5 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_19 PF13245.6 CBZ32387.1 - 0.12 12.7 0.3 12 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 CBZ32387.1 - 0.16 11.8 0.5 20 4.9 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_22 PF13401.6 CBZ32387.1 - 0.2 11.9 0.3 4.5 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CBZ32387.1 - 0.27 10.8 0.8 6.6 6.3 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CBZ32387.1 - 0.51 10.5 2.0 50 4.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain TMEM208_SND2 PF05620.11 CBZ32387.1 - 0.85 9.4 0.0 0.85 9.4 0.0 4.5 4 1 0 5 5 3 0 SRP-independent targeting protein 2/TMEM208 ABC2_membrane PF01061.24 CBZ32387.1 - 2.5 7.5 55.6 0.01 15.2 15.1 4.2 4 0 0 4 4 4 0 ABC-2 type transporter TatD_DNase PF01026.21 CBZ32388.1 - 6.5e-47 160.0 0.0 8.8e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 CBZ32388.1 - 0.00019 21.3 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase ABC2_membrane_3 PF12698.7 CBZ32389.1 - 5.6e-66 223.0 40.6 4.4e-43 147.7 16.2 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ32389.1 - 1.6e-51 174.4 0.0 6.1e-27 94.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ32389.1 - 2.5e-18 67.0 0.9 1.7e-06 28.1 0.0 4.8 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ32389.1 - 1e-08 34.9 0.0 0.034 13.6 0.0 3.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBZ32389.1 - 6.1e-05 23.0 0.1 0.082 12.8 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 CBZ32389.1 - 0.00022 21.8 2.8 0.16 12.4 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.6 CBZ32389.1 - 0.00066 19.5 0.0 1.7 8.2 0.0 3.9 5 0 0 5 5 5 1 AAA ATPase domain AAA_29 PF13555.6 CBZ32389.1 - 0.0013 18.4 0.1 0.26 11.0 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 CBZ32389.1 - 0.0017 18.1 0.9 0.44 10.1 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 CBZ32389.1 - 0.0087 16.3 0.0 8.7 6.7 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 CBZ32389.1 - 0.013 15.2 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CBZ32389.1 - 0.027 13.8 0.0 12 5.1 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin DUF4162 PF13732.6 CBZ32389.1 - 0.029 15.1 0.0 15 6.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_16 PF13191.6 CBZ32389.1 - 0.046 14.1 0.0 3.1 8.2 0.0 2.9 3 0 0 3 3 2 0 AAA ATPase domain AAA PF00004.29 CBZ32389.1 - 0.085 13.3 0.1 7 7.1 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MukB PF04310.12 CBZ32389.1 - 0.11 12.3 0.2 18 5.1 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_19 PF13245.6 CBZ32389.1 - 0.11 12.8 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 CBZ32389.1 - 0.12 11.8 0.1 5.6 6.4 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBZ32389.1 - 0.13 12.3 0.3 19 5.4 0.1 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 CBZ32389.1 - 0.19 12.0 0.1 6.9 6.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CBZ32389.1 - 0.2 11.2 0.5 6.3 6.3 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 CBZ32389.1 - 0.55 10.5 3.9 7.8 6.7 0.1 3.7 4 0 0 4 4 4 0 AAA domain ABC2_membrane PF01061.24 CBZ32389.1 - 1.2 8.5 41.2 0.37 10.2 13.5 3.4 3 0 0 3 3 3 0 ABC-2 type transporter DUF4478 PF14793.6 CBZ32390.1 - 0.18 11.7 0.8 0.61 10.0 0.1 2.1 2 1 1 3 3 3 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases HEAT PF02985.22 CBZ32391.1 - 0.0017 18.4 11.0 6.3 7.3 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.23 CBZ32391.1 - 0.014 15.5 0.2 0.014 15.5 0.2 3.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 CBZ32391.1 - 0.02 13.5 4.3 1.6 7.2 1.6 2.5 2 1 0 2 2 2 0 Adaptin N terminal region Rcd1 PF04078.13 CBZ32391.1 - 0.022 14.1 0.1 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like HTH_Tnp_Mu_1 PF02316.16 CBZ32391.1 - 0.059 13.6 1.3 2.3 8.4 0.2 2.8 2 1 1 3 3 3 0 Mu DNA-binding domain HEAT_2 PF13646.6 CBZ32391.1 - 0.068 13.6 0.9 0.068 13.6 0.9 4.2 3 2 1 4 4 4 0 HEAT repeats PapD-like PF14874.6 CBZ32393.1 - 8.6e-48 160.7 0.9 1.7e-47 159.8 0.9 1.5 1 0 0 1 1 1 1 Flagellar-associated PapD-like Nodulin-like PF06813.13 CBZ32394.1 - 2.3e-16 60.1 11.0 2.3e-16 60.1 11.0 2.9 3 0 0 3 3 3 1 Nodulin-like MFS_1 PF07690.16 CBZ32394.1 - 7.3e-10 38.3 47.9 3.5e-06 26.2 16.6 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF3188 PF11384.8 CBZ32394.1 - 1.2 8.8 6.4 1.3 8.8 1.5 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DUF3450 PF11932.8 CBZ32395.1 - 0.0065 15.8 3.4 0.01 15.2 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 CBZ32395.1 - 0.018 15.3 4.4 0.1 12.9 4.4 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Uso1_p115_C PF04871.13 CBZ32395.1 - 0.019 15.3 8.8 0.026 14.9 8.8 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DivIC PF04977.15 CBZ32395.1 - 0.024 14.4 1.2 0.024 14.4 1.2 2.1 1 1 1 2 2 2 0 Septum formation initiator HAUS-augmin3 PF14932.6 CBZ32395.1 - 0.024 14.2 3.4 0.033 13.8 3.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FPP PF05911.11 CBZ32395.1 - 0.053 11.7 6.7 0.064 11.4 6.7 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil KASH_CCD PF14662.6 CBZ32395.1 - 0.08 12.8 6.1 0.11 12.3 6.1 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH KxDL PF10241.9 CBZ32395.1 - 0.089 13.1 4.6 0.13 12.6 1.6 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein DUF4175 PF13779.6 CBZ32395.1 - 0.12 10.2 5.3 0.14 10.0 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CENP-H PF05837.12 CBZ32395.1 - 0.97 9.9 5.7 1.4 9.4 5.2 1.4 1 1 0 1 1 1 0 Centromere protein H (CENP-H) DUF4140 PF13600.6 CBZ32395.1 - 1 9.8 5.9 6.9 7.2 6.0 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 CBZ32395.1 - 3.1 8.5 6.8 0.71 10.5 3.1 1.8 2 1 0 2 2 2 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 CBZ32395.1 - 6.8 6.8 8.7 1.3 9.1 4.6 1.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Ribosomal_L4 PF00573.22 CBZ32396.1 - 1.9e-10 40.8 0.0 4e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L4/L1 family SH3_9 PF14604.6 CBZ32398.1 - 2.6e-11 43.2 0.0 4.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBZ32398.1 - 6.2e-08 32.1 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBZ32398.1 - 6.6e-08 32.1 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TMEM247 PF15444.6 CBZ32398.1 - 0.71 9.9 3.5 9.4 6.2 0.1 2.3 2 0 0 2 2 2 0 Transmembrane protein 247 IF-2B PF01008.17 CBZ32399.1 - 1.6e-21 76.8 0.8 3.6e-17 62.5 0.5 3.0 2 1 0 2 2 2 2 Initiation factor 2 subunit family RMMBL PF07521.12 CBZ32399.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain PITH PF06201.13 CBZ32400.1 - 3.7e-25 88.9 0.0 5.2e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 PITH domain Proteasome PF00227.26 CBZ32401.1 - 5e-41 140.3 0.5 5.9e-41 140.0 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Herp-Cyclin PF09241.10 CBZ32401.1 - 0.062 13.9 0.0 1.3 9.7 0.0 2.4 2 0 0 2 2 2 0 Herpesviridae viral cyclin DAP3 PF10236.9 CBZ32402.1 - 1.8e-23 83.2 0.0 3.2e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 CBZ32402.1 - 0.017 15.1 0.0 0.057 13.3 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CBZ32402.1 - 0.028 14.8 0.0 0.057 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 CBZ32402.1 - 0.087 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Bmt2 PF11968.8 CBZ32404.1 - 0.068 13.0 0.6 0.61 9.9 0.3 2.1 2 0 0 2 2 2 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Isochorismatase PF00857.20 CBZ32405.1 - 3.7e-15 56.5 0.1 6.1e-15 55.8 0.1 1.4 1 1 0 1 1 1 1 Isochorismatase family TPR_7 PF13176.6 CBZ32409.1 - 0.027 14.5 0.0 3.6 7.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ32409.1 - 0.09 13.3 1.1 2.6 8.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Plus-3 PF03126.18 CBZ32410.1 - 1.9e-20 73.4 0.0 3.6e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Plus-3 domain zf-C3HC4_3 PF13920.6 CBZ32410.1 - 7.7e-08 32.1 17.1 1.2e-07 31.5 17.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SelB-wing_1 PF09105.10 CBZ32410.1 - 0.11 12.5 0.8 0.2 11.7 0.8 1.4 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Vps39_2 PF10367.9 CBZ32410.1 - 0.46 10.9 6.5 1 9.8 6.5 1.7 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 FYVE PF01363.21 CBZ32411.1 - 5.3e-09 36.1 4.7 2.3e-08 34.1 4.7 2.2 1 0 0 1 1 1 1 FYVE zinc finger Tropomyosin_1 PF12718.7 CBZ32412.1 - 1.5e-05 25.2 8.0 1.5e-05 25.2 8.0 6.6 1 1 7 8 8 8 1 Tropomyosin like DUF1664 PF07889.12 CBZ32412.1 - 0.0022 18.0 2.0 0.0022 18.0 2.0 8.7 5 3 4 9 9 9 3 Protein of unknown function (DUF1664) AAA_13 PF13166.6 CBZ32412.1 - 0.0027 16.4 9.9 0.0027 16.4 9.9 3.5 1 1 2 3 3 3 1 AAA domain TolA_bind_tri PF16331.5 CBZ32412.1 - 0.0046 17.0 7.0 0.0046 17.0 7.0 8.7 6 3 5 11 11 11 2 TolA binding protein trimerisation XhlA PF10779.9 CBZ32412.1 - 0.69 10.2 8.5 48 4.2 0.0 5.9 5 0 0 5 5 5 0 Haemolysin XhlA Fib_alpha PF08702.10 CBZ32412.1 - 2.4 8.4 36.4 0.45 10.7 2.8 6.3 2 2 4 7 7 7 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 CBZ32413.1 - 8.5e-39 133.5 0.0 2.2e-18 66.6 0.0 3.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32413.1 - 1e-16 61.0 0.0 4.4e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ32413.1 - 0.00092 19.2 0.5 0.54 10.1 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ32413.1 - 0.045 12.5 0.0 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase LRR_8 PF13855.6 CBZ32415.1 - 3.9e-12 45.7 1.4 0.00018 21.2 0.1 3.8 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 CBZ32415.1 - 4.2e-10 39.7 2.7 0.0033 17.8 0.1 4.0 2 2 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ32415.1 - 0.13 11.7 0.0 0.82 9.1 0.0 1.9 2 0 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 CBZ32415.1 - 2.9 8.2 11.9 61 4.1 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeat Glyco_transf_22 PF03901.17 CBZ32416.1 - 1.5e-53 182.6 22.8 4.9e-41 141.3 18.6 3.1 3 0 0 3 3 3 3 Alg9-like mannosyltransferase family UCH PF00443.29 CBZ32419.1 - 3.6e-22 79.1 0.0 2.9e-20 72.9 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ32419.1 - 0.0023 17.6 0.0 9.3 5.7 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase AAA PF00004.29 CBZ32421.1 - 2.7e-45 154.0 0.1 1.4e-44 151.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CBZ32421.1 - 1.1e-09 38.1 0.8 3.1e-09 36.6 0.0 2.2 3 0 0 3 3 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CBZ32421.1 - 2.5e-09 36.8 0.0 5.8e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBZ32421.1 - 1.9e-08 34.4 0.1 7.3e-08 32.5 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ32421.1 - 1.6e-07 31.9 0.6 1.9e-05 25.1 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 CBZ32421.1 - 7.1e-07 29.5 0.1 3.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CBZ32421.1 - 2.2e-05 24.8 1.9 0.0081 16.4 0.7 3.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 CBZ32421.1 - 8.8e-05 21.8 0.0 0.00017 20.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBZ32421.1 - 0.00043 20.0 0.0 0.0012 18.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CBZ32421.1 - 0.00045 20.5 0.0 0.00094 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBZ32421.1 - 0.00053 19.6 0.1 0.0025 17.4 0.0 2.0 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 CBZ32421.1 - 0.00074 20.1 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CBZ32421.1 - 0.0011 18.9 1.2 0.05 13.5 0.0 3.4 3 1 1 4 4 4 1 NACHT domain AAA_30 PF13604.6 CBZ32421.1 - 0.0021 17.8 0.1 0.0067 16.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CBZ32421.1 - 0.0022 17.9 0.2 0.0089 15.9 0.1 2.1 3 0 0 3 3 2 1 NTPase TniB PF05621.11 CBZ32421.1 - 0.0023 17.4 0.3 0.31 10.4 0.0 3.0 3 1 1 4 4 4 1 Bacterial TniB protein AAA_3 PF07726.11 CBZ32421.1 - 0.0032 17.3 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CBZ32421.1 - 0.0035 17.5 0.0 0.0081 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBZ32421.1 - 0.0038 17.3 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBZ32421.1 - 0.0074 15.7 0.1 0.021 14.2 0.1 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CBZ32421.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CBZ32421.1 - 0.015 14.6 0.0 0.038 13.2 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 CBZ32421.1 - 0.02 14.6 0.1 0.047 13.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CBZ32421.1 - 0.022 14.1 2.2 1 8.7 0.0 2.9 3 0 0 3 3 3 0 KaiC RNA_helicase PF00910.22 CBZ32421.1 - 0.026 14.9 0.0 0.063 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CBZ32421.1 - 0.027 14.8 0.2 0.088 13.1 0.1 1.8 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 CBZ32421.1 - 0.03 14.1 0.6 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CBZ32421.1 - 0.031 14.0 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CBZ32421.1 - 0.031 13.8 0.6 0.2 11.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CBZ32421.1 - 0.034 13.8 0.1 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 CBZ32421.1 - 0.038 13.9 1.0 0.22 11.4 0.1 2.4 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 CBZ32421.1 - 0.044 13.6 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.27 CBZ32421.1 - 0.049 14.1 0.1 0.21 12.1 0.0 2.3 2 2 0 2 2 2 0 ABC transporter cobW PF02492.19 CBZ32421.1 - 0.071 12.7 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ins_P5_2-kin PF06090.12 CBZ32421.1 - 0.094 12.1 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase EzrA PF06160.12 CBZ32421.1 - 0.15 10.2 2.9 0.21 9.7 2.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF465 PF04325.13 CBZ32421.1 - 0.21 11.7 1.2 0.43 10.7 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF465) HAGH_C PF16123.5 CBZ32422.1 - 2.8e-07 30.9 0.0 6.7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CBZ32422.1 - 4.4e-05 23.6 3.9 0.00018 21.6 3.9 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBZ32422.1 - 0.044 13.3 0.1 0.095 12.2 0.1 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain tRNA-synt_1e PF01406.19 CBZ32425.1 - 3.2e-114 381.3 0.0 4.7e-114 380.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1 PF00133.22 CBZ32425.1 - 0.0014 17.0 0.1 0.093 11.0 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CBZ32425.1 - 0.0014 17.4 2.9 0.0062 15.3 0.0 2.9 4 0 0 4 4 4 1 tRNA synthetases class I (M) tRNA-synt_1c PF00749.21 CBZ32425.1 - 0.0023 16.9 0.3 0.0065 15.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain Helicase_C PF00271.31 CBZ32426.1 - 7.2e-05 23.1 0.0 0.00018 21.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 CBZ32426.1 - 0.00062 20.0 0.1 0.0022 18.2 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) zf-met PF12874.7 CBZ32426.1 - 0.02 15.3 2.9 0.046 14.1 2.9 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBZ32426.1 - 0.074 13.4 1.4 0.15 12.4 1.4 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding SET PF00856.28 CBZ32427.1 - 3.2e-05 24.4 1.1 0.68 10.3 0.4 3.3 1 1 1 2 2 2 2 SET domain Orn_Arg_deC_N PF02784.16 CBZ32428.1 - 1.5e-86 289.8 0.0 2e-86 289.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CBZ32428.1 - 4.5e-12 46.1 0.0 2.6e-11 43.6 0.0 2.2 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SAC3_GANP PF03399.16 CBZ32430.1 - 9.3e-15 54.8 0.3 4.7e-14 52.4 0.3 2.1 1 1 0 1 1 1 1 SAC3/GANP family LrgB PF04172.16 CBZ32431.1 - 0.0027 17.3 0.0 0.0076 15.8 0.0 1.7 1 0 0 1 1 1 1 LrgB-like family Myotub-related PF06602.14 CBZ32432.1 - 2.3e-60 204.4 0.0 2.2e-31 109.1 0.0 2.9 3 0 0 3 3 3 2 Myotubularin-like phosphatase domain DUF4722 PF15849.5 CBZ32433.1 - 0.055 13.2 1.3 0.1 12.3 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4722) NOT2_3_5 PF04153.18 CBZ32435.1 - 5.9e-22 78.2 0.4 5.9e-22 78.2 0.4 3.3 3 1 0 3 3 3 1 NOT2 / NOT3 / NOT5 family GST_N PF02798.20 CBZ32436.1 - 5.2e-10 39.5 0.0 9.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CBZ32436.1 - 5.9e-10 39.4 0.0 2.3e-09 37.6 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBZ32436.1 - 1.2e-07 31.9 0.0 2.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CBZ32436.1 - 0.00035 20.7 0.0 0.00091 19.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBZ32436.1 - 0.007 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FA_synthesis PF02504.15 CBZ32436.1 - 0.13 11.3 0.3 0.64 9.0 0.1 1.9 2 0 0 2 2 2 0 Fatty acid synthesis protein GST_C_2 PF13410.6 CBZ32436.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PUF PF00806.19 CBZ32438.1 - 9.4e-35 116.4 7.8 8e-06 25.3 0.1 7.6 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat DUF4357 PF14267.6 CBZ32438.1 - 0.5 10.3 0.0 0.5 10.3 0.0 6.1 8 0 0 8 8 8 0 Domain of unknown function (DUF4357) NAD_binding_10 PF13460.6 CBZ32439.1 - 0.0029 17.5 0.2 0.31 10.9 0.1 2.4 2 0 0 2 2 2 2 NAD(P)H-binding DapB_N PF01113.20 CBZ32439.1 - 0.0084 16.2 0.1 0.026 14.6 0.1 1.9 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 CBZ32439.1 - 0.023 14.2 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Acetyltransf_8 PF13523.6 CBZ32439.1 - 0.1 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain S1-P1_nuclease PF02265.16 CBZ32440.1 - 4.2e-60 203.7 0.0 5e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease DUF866 PF05907.13 CBZ32442.1 - 1.1e-36 126.1 0.0 1.3e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Elf1 PF05129.13 CBZ32442.1 - 0.026 14.6 0.7 0.059 13.4 0.0 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Fe-ADH PF00465.19 CBZ32443.1 - 4.8e-06 25.6 0.0 4.8e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Bromodomain PF00439.25 CBZ32444.1 - 0.018 15.1 0.0 5.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Bromodomain WW PF00397.26 CBZ32452.1 - 2.9e-09 36.8 0.1 5.8e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 WW domain Taeniidae_ag PF05596.11 CBZ32452.1 - 2.6 8.1 8.3 1.4 8.9 0.5 3.7 3 0 0 3 3 3 0 Taeniidae antigen ATP-synt_F PF01990.17 CBZ32453.1 - 9.5e-34 115.6 0.1 1.2e-33 115.3 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PGI PF00342.19 CBZ32454.1 - 2.7e-265 880.5 3.8 3.1e-265 880.3 3.8 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4473 PF14747.6 CBZ32454.1 - 0.0049 17.4 0.1 0.015 15.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) OsmC PF02566.19 CBZ32455.1 - 0.0064 16.9 0.0 0.016 15.7 0.0 1.5 1 1 0 1 1 1 1 OsmC-like protein E3_binding PF02817.17 CBZ32455.1 - 0.08 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 e3 binding domain Cep57_MT_bd PF06657.13 CBZ32456.1 - 0.068 13.6 0.7 0.068 13.6 0.7 2.7 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Prok-TraM PF09228.10 CBZ32456.1 - 3.3 8.1 6.7 0.47 10.8 1.2 2.2 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Fez1 PF06818.15 CBZ32456.1 - 7.1 7.0 12.5 0.79 10.1 7.4 1.9 2 0 0 2 2 2 0 Fez1 TPR_19 PF14559.6 CBZ32457.1 - 0.00029 21.3 29.9 0.02 15.4 1.1 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ32457.1 - 0.00031 20.4 8.9 0.033 14.0 0.8 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ32457.1 - 0.00096 19.2 0.9 0.0099 15.9 0.5 2.9 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 CBZ32457.1 - 0.003 17.6 2.0 0.003 17.6 2.0 7.7 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ32457.1 - 0.028 14.6 13.6 1.6 9.2 0.3 7.0 10 0 0 10 10 10 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ32457.1 - 0.051 13.8 13.1 0.09 13.0 1.0 4.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 AWPM-19 PF05512.11 CBZ32457.1 - 0.099 12.8 1.2 0.27 11.4 1.2 1.8 1 0 0 1 1 1 0 AWPM-19-like family TPR_14 PF13428.6 CBZ32457.1 - 3.6 8.7 36.5 0.069 14.0 5.2 8.8 9 1 1 10 10 10 0 Tetratricopeptide repeat FUSC_2 PF13515.6 CBZ32458.1 - 1.5e-16 60.7 14.0 1.8e-16 60.4 9.8 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 CBZ32458.1 - 0.16 12.1 4.4 0.37 10.9 4.4 1.6 1 0 0 1 1 1 0 Aromatic acid exporter family member 1 Ses_B PF17046.5 CBZ32458.1 - 2.3 8.3 5.2 7.1 6.7 0.1 2.6 2 0 0 2 2 2 0 SesB domain on fungal death-pathway protein FUSC_2 PF13515.6 CBZ32459.1 - 1.4e-11 44.6 20.6 1.9e-11 44.2 4.9 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ALMT PF11744.8 CBZ32459.1 - 0.46 9.3 2.5 0.39 9.5 0.2 1.9 2 0 0 2 2 2 0 Aluminium activated malate transporter Sulfatase PF00884.23 CBZ32460.1 - 5.2e-05 22.8 0.1 0.0002 20.9 0.1 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CBZ32460.1 - 0.00034 20.3 0.1 0.004 16.8 0.1 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase TPR_1 PF00515.28 CBZ32461.1 - 9.6e-17 60.0 14.7 6.5e-05 22.6 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ32461.1 - 1.2e-16 59.4 0.3 2.5e-05 24.1 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ32461.1 - 3.1e-16 58.1 26.4 0.0015 18.5 0.0 8.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ32461.1 - 7.4e-12 45.6 10.1 4.9e-05 23.7 0.1 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ32461.1 - 3.8e-11 42.5 18.1 1.5e-05 24.6 0.1 4.7 4 1 1 5 5 5 2 TPR repeat TPR_14 PF13428.6 CBZ32461.1 - 1.6e-10 40.9 25.7 0.0001 22.8 0.2 7.4 6 3 3 9 9 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ32461.1 - 5.2e-07 30.2 37.5 5.1e-05 23.8 0.6 6.5 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ32461.1 - 1.3e-05 25.4 26.0 0.17 12.2 1.8 6.2 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_15 PF13429.6 CBZ32461.1 - 1.5e-05 24.4 7.3 4e-05 23.0 7.3 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC8 PF04049.13 CBZ32461.1 - 0.00013 22.0 0.0 0.00066 19.7 0.0 2.1 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_9 PF13371.6 CBZ32461.1 - 0.0013 18.9 17.0 0.15 12.2 0.7 5.1 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ32461.1 - 0.0014 18.9 2.4 1.7 9.2 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ32461.1 - 0.0066 16.4 17.8 2.5 8.3 0.2 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ32461.1 - 0.012 15.8 20.3 0.017 15.3 0.8 5.8 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 FAT PF02259.23 CBZ32461.1 - 0.014 14.6 0.3 0.16 11.2 0.3 2.5 1 1 0 1 1 1 0 FAT domain TPR_10 PF13374.6 CBZ32461.1 - 0.18 11.7 13.8 0.3 11.0 0.9 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ32461.1 - 0.34 11.6 9.4 1.9 9.3 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 CBZ32463.1 - 4.2e-31 108.4 0.0 5.5e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PPL5 PF18168.1 CBZ32464.1 - 8.1e-144 478.8 0.0 1e-143 478.4 0.0 1.1 1 0 0 1 1 1 1 Prim-pol family 5 PriCT_2 PF08707.11 CBZ32464.1 - 6.6e-13 48.8 0.1 2.4e-12 47.1 0.1 2.0 1 0 0 1 1 1 1 Primase C terminal 2 (PriCT-2) MCM2_N PF12619.8 CBZ32464.1 - 0.031 14.6 0.7 0.031 14.6 0.7 1.9 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 DUF1682 PF07946.14 CBZ32465.1 - 0.74 9.0 8.3 1.2 8.2 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SAPS PF04499.15 CBZ32465.1 - 8 5.1 7.2 12 4.5 7.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CBZ32465.1 - 8.5 5.0 7.1 12 4.5 7.1 1.2 1 0 0 1 1 1 0 Presenilin Metallophos PF00149.28 CBZ32466.1 - 4.1e-29 102.5 0.0 7.5e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EF-hand_1 PF00036.32 CBZ32466.1 - 0.0008 18.8 0.1 0.13 11.9 0.0 3.1 3 0 0 3 3 3 1 EF hand zf-TRAF PF02176.18 CBZ32466.1 - 0.0016 19.1 3.3 0.0016 19.1 3.3 3.2 1 1 2 3 3 3 1 TRAF-type zinc finger EF-hand_7 PF13499.6 CBZ32466.1 - 0.0028 18.1 0.2 0.058 13.8 0.0 2.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ32466.1 - 0.0047 16.7 0.8 0.34 10.9 0.0 4.0 4 1 1 5 5 5 1 EF-hand domain EF-hand_8 PF13833.6 CBZ32466.1 - 0.11 12.3 0.2 3.1 7.7 0.1 2.8 1 1 1 2 2 2 0 EF-hand domain pair zf_UBZ PF18439.1 CBZ32466.1 - 0.13 11.9 0.0 0.13 11.9 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger PPP5 PF08321.12 CBZ32466.1 - 0.17 12.2 0.0 0.65 10.3 0.0 2.0 2 0 0 2 2 2 0 PPP5 TPR repeat region zinc_ribbon_2 PF13240.6 CBZ32466.1 - 1.5 8.7 11.4 1.6 8.6 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 CBZ32466.1 - 6.4 6.9 15.5 0.51 10.4 8.0 2.5 2 0 0 2 2 2 0 Double zinc ribbon AAA-ATPase_like PF09820.9 CBZ32467.1 - 0.24 10.8 1.6 2.5 7.4 0.1 2.2 2 0 0 2 2 2 0 Predicted AAA-ATPase BBL5 PF07289.11 CBZ32468.1 - 1.8e-133 444.7 0.0 2.1e-133 444.5 0.0 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Voldacs PF03517.13 CBZ32468.1 - 0.0098 16.0 0.0 0.5 10.5 0.0 2.5 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 CBZ32468.1 - 0.011 15.9 0.0 0.91 9.8 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 LRR_6 PF13516.6 CBZ32470.1 - 4.2e-22 76.3 21.9 0.055 13.5 0.0 11.5 11 0 0 11 11 11 8 Leucine Rich repeat LRR_4 PF12799.7 CBZ32470.1 - 2e-08 34.4 5.9 0.15 12.5 0.0 7.1 6 1 1 7 7 7 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ32470.1 - 3.5e-06 26.8 1.3 7.8 7.5 0.0 7.2 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.6 CBZ32470.1 - 0.00012 21.8 11.2 4.6 7.1 0.4 6.8 6 2 0 6 6 6 2 Leucine rich repeat NCOA_u2 PF16665.5 CBZ32470.1 - 0.17 12.2 1.0 0.43 10.9 1.0 1.6 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein DUF962 PF06127.11 CBZ32471.1 - 6.3e-25 87.1 0.2 7.2e-25 86.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) DUF4491 PF14898.6 CBZ32471.1 - 0.019 15.4 0.2 0.029 14.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) HlyE PF06109.13 CBZ32471.1 - 0.038 13.3 0.0 0.044 13.1 0.0 1.0 1 0 0 1 1 1 0 Haemolysin E (HlyE) UCR_Fe-S_N PF10399.9 CBZ32471.1 - 0.11 11.8 0.3 0.11 11.8 0.3 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DUF962 PF06127.11 CBZ32472.1 - 5.6e-24 84.1 0.0 6.3e-24 83.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) UPF0126 PF03458.13 CBZ32472.1 - 0.017 15.0 0.5 0.027 14.4 0.5 1.3 1 0 0 1 1 1 0 UPF0126 domain YhhN PF07947.14 CBZ32472.1 - 0.029 14.0 0.1 0.038 13.6 0.1 1.2 1 0 0 1 1 1 0 YhhN family DnaJ PF00226.31 CBZ32476.1 - 5.6e-12 45.6 0.0 1.7e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain DUF4875 PF16175.5 CBZ32476.1 - 0.0097 16.0 0.1 0.025 14.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4875) zf-C3HC4_3 PF13920.6 CBZ32476.1 - 0.17 11.8 15.5 0.037 13.9 11.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PDZ_6 PF17820.1 CBZ32477.1 - 0.02 14.8 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 PDZ domain KIF1B PF12423.8 CBZ32477.1 - 0.022 15.2 0.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 0 Kinesin protein 1B PDZ PF00595.24 CBZ32477.1 - 0.026 14.9 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain PDZ_2 PF13180.6 CBZ32477.1 - 0.039 14.3 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 PDZ domain SlyX PF04102.12 CBZ32478.1 - 0.11 13.2 1.0 0.39 11.4 1.0 2.0 1 0 0 1 1 1 0 SlyX DUF4201 PF13870.6 CBZ32478.1 - 0.29 10.8 0.4 0.45 10.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Mcl1_mid PF12341.8 CBZ32479.1 - 1.5e-57 195.3 0.0 2.3e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region DUF2121 PF09894.9 CBZ32479.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) Oxidored_FMN PF00724.20 CBZ32480.1 - 2.8e-78 263.6 0.0 3.8e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 CBZ32480.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein Oxidored_FMN PF00724.20 CBZ32481.1 - 1.5e-133 445.3 0.0 1.6e-73 247.9 0.0 2.1 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family TmoB PF06234.12 CBZ32481.1 - 1.4 9.1 4.7 49 4.1 2.1 3.0 2 1 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) AadA_C PF18280.1 CBZ32481.1 - 1.7 8.9 3.6 33 4.7 0.3 3.2 3 1 0 3 3 3 0 Aminoglycoside adenyltransferase C-terminal domain T3SS_TC PF06511.11 CBZ32483.1 - 0.021 14.2 2.5 0.037 13.4 2.5 1.3 1 0 0 1 1 1 0 Type III secretion systems tip complex components CSD PF00313.22 CBZ32485.1 - 0.0014 18.5 0.0 0.05 13.4 0.0 2.5 2 0 0 2 2 2 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 CBZ32485.1 - 0.1 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 Ribonuclease B OB domain ABC_tran PF00005.27 CBZ32486.1 - 7.2e-11 42.7 0.0 0.00017 22.1 0.1 2.7 2 1 0 2 2 2 2 ABC transporter AAA_30 PF13604.6 CBZ32486.1 - 0.0056 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBZ32486.1 - 0.019 14.9 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 CBZ32486.1 - 0.023 14.5 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CBZ32486.1 - 0.03 14.7 0.1 0.1 13.0 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CBZ32486.1 - 0.055 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane PF00664.23 CBZ32486.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region AAA_22 PF13401.6 CBZ32486.1 - 0.17 12.1 0.0 0.87 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain SVIP PF15811.5 CBZ32487.1 - 0.079 13.4 0.2 0.079 13.4 0.2 3.6 5 0 0 5 5 5 0 Small VCP/p97-interacting protein PSCyt3 PF07627.11 CBZ32487.1 - 0.19 12.0 0.7 0.51 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) SNARE_assoc PF09335.11 CBZ32488.1 - 1.7e-20 73.7 5.6 4.5e-20 72.3 5.6 1.8 1 0 0 1 1 1 1 SNARE associated Golgi protein XhlA PF10779.9 CBZ32488.1 - 0.23 11.7 0.0 0.43 10.8 0.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA FtsK_4TM PF13491.6 CBZ32488.1 - 2.1 8.0 7.8 2.6 7.7 3.2 2.4 2 1 0 2 2 2 0 4TM region of DNA translocase FtsK/SpoIIIE zf-RING_UBOX PF13445.6 CBZ32489.1 - 1.2e-05 25.2 9.0 3.2e-05 23.8 9.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ32489.1 - 0.00028 20.7 8.6 0.00028 20.7 8.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ32489.1 - 0.0092 15.8 10.5 0.0092 15.8 10.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sugarporin_N PF11471.8 CBZ32489.1 - 0.014 15.3 0.3 0.014 15.3 0.3 4.7 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension MPS2 PF17060.5 CBZ32489.1 - 0.048 12.9 2.9 0.27 10.5 0.1 2.3 2 0 0 2 2 2 0 Monopolar spindle protein 2 zf-RING_6 PF14835.6 CBZ32489.1 - 0.9 9.5 9.3 2.4 8.1 9.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 CBZ32489.1 - 1.8 8.9 19.4 0.59 10.5 14.1 2.6 2 0 0 2 2 2 0 Ring finger domain Peptidase_M1 PF01433.20 CBZ32490.1 - 1.2e-49 168.9 0.0 1.8e-49 168.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBZ32490.1 - 2.5e-20 73.5 0.0 9.6e-15 55.2 0.0 2.3 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CBZ32490.1 - 4e-07 29.9 0.0 7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Methyltransf_31 PF13847.6 CBZ32492.1 - 1.4e-12 47.7 0.1 2.2e-12 47.0 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ32492.1 - 2.4e-12 47.4 0.1 6.1e-12 46.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CBZ32492.1 - 3.8e-12 46.2 0.0 6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CBZ32492.1 - 5.7e-09 36.5 0.0 1.4e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ32492.1 - 6e-08 32.7 0.0 8.3e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBZ32492.1 - 5.5e-07 29.3 0.2 9.9e-07 28.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CBZ32492.1 - 4.6e-06 27.3 0.0 9.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CBZ32492.1 - 5.3e-06 25.6 0.1 7.7e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 CBZ32492.1 - 6e-05 22.5 0.6 0.00014 21.4 0.6 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 CBZ32492.1 - 6.8e-05 22.3 0.1 0.00011 21.7 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 CBZ32492.1 - 0.00011 22.2 0.1 0.00018 21.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 CBZ32492.1 - 0.00047 20.1 0.0 0.00073 19.4 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 CBZ32492.1 - 0.0077 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CBZ32492.1 - 0.0097 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CBZ32492.1 - 0.01 16.0 0.0 0.017 15.3 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase NodS PF05401.11 CBZ32492.1 - 0.01 15.5 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Met_10 PF02475.16 CBZ32492.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.6 CBZ32492.1 - 0.044 14.8 0.0 0.089 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CBZ32492.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SET PF00856.28 CBZ32495.1 - 3.4e-11 43.8 0.0 8.3e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 CBZ32495.1 - 0.00065 19.7 8.9 0.00065 19.7 8.9 2.8 2 1 0 2 2 2 1 MYND finger TPR_2 PF07719.17 CBZ32495.1 - 0.0061 16.6 0.3 0.27 11.5 0.8 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ32495.1 - 0.044 14.4 0.5 5.7 7.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ32495.1 - 0.089 13.1 0.9 0.32 11.3 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ32495.1 - 0.21 11.5 1.2 3.6 7.6 0.5 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RNase_H2_suC PF08615.11 CBZ32496.1 - 1.4e-07 31.8 0.0 3.9e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) FAM91_C PF14648.6 CBZ32497.1 - 6.8e-122 407.4 0.0 2.9e-120 402.0 0.0 2.1 1 1 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 CBZ32497.1 - 3.6e-106 354.9 0.3 4.8e-106 354.6 0.3 1.1 1 0 0 1 1 1 1 FAM91 N-terminus Phage_portal PF04860.12 CBZ32497.1 - 0.08 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 Phage portal protein Vps39_2 PF10367.9 CBZ32498.1 - 5.1e-27 94.5 0.1 1.2e-26 93.3 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 CBZ32498.1 - 5.7e-10 39.4 0.3 1.2e-08 35.1 0.1 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 CBZ32498.1 - 3.6e-05 23.7 0.1 0.00039 20.3 0.1 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Rad50_zn_hook PF04423.14 CBZ32498.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif TPR_14 PF13428.6 CBZ32498.1 - 0.68 10.9 10.0 15 6.8 2.9 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 CBZ32499.1 - 0.0023 17.6 0.1 0.013 15.2 0.0 2.2 2 1 1 3 3 3 1 alpha/beta hydrolase fold DLH PF01738.18 CBZ32499.1 - 0.0054 16.3 0.1 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 CBZ32499.1 - 0.016 15.9 0.1 0.043 14.4 0.0 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CBZ32499.1 - 0.13 12.1 0.1 10 5.9 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CBZ32499.1 - 0.14 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family FSIP1 PF15554.6 CBZ32499.1 - 0.17 10.9 0.1 0.26 10.4 0.1 1.1 1 0 0 1 1 1 0 FSIP1 family DUF3580 PF12117.8 CBZ32500.1 - 0.084 13.1 0.4 3 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) WD40 PF00400.32 CBZ32501.1 - 4.7e-10 39.9 3.1 0.11 13.5 0.2 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.8 CBZ32501.1 - 0.018 13.7 0.0 0.088 11.4 0.0 2.0 1 1 0 1 1 1 0 Nucleoporin Nup120/160 LisH PF08513.11 CBZ32501.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 LisH PQQ PF01011.21 CBZ32501.1 - 0.63 10.1 2.6 1.2 9.2 0.2 2.6 3 0 0 3 3 3 0 PQQ enzyme repeat Prenyltransf PF01255.19 CBZ32502.1 - 1.9e-59 200.9 0.2 5.3e-56 189.7 0.1 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase Maf1 PF09174.10 CBZ32502.1 - 0.007 16.5 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator SKA2 PF16740.5 CBZ32503.1 - 0.023 14.5 1.2 0.58 10.0 0.1 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Snapin_Pallidin PF14712.6 CBZ32503.1 - 0.047 14.1 0.5 0.28 11.6 0.4 2.1 2 0 0 2 2 2 0 Snapin/Pallidin SCP-1 PF05483.12 CBZ32503.1 - 0.067 11.2 0.4 0.08 10.9 0.4 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Exonuc_VII_L PF02601.15 CBZ32503.1 - 0.068 12.7 0.2 0.079 12.5 0.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Transmemb_17 PF09799.9 CBZ32503.1 - 0.11 13.2 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein MnmE_helical PF12631.7 CBZ32503.1 - 0.11 12.7 0.2 0.18 12.0 0.2 1.3 1 0 0 1 1 1 0 MnmE helical domain YPEB PF14620.6 CBZ32503.1 - 0.11 11.8 0.2 0.16 11.3 0.2 1.3 1 0 0 1 1 1 0 YpeB sporulation PspB PF06667.12 CBZ32503.1 - 0.11 12.6 0.4 0.26 11.4 0.4 1.6 1 0 0 1 1 1 0 Phage shock protein B DUF4795 PF16043.5 CBZ32503.1 - 0.12 12.0 0.3 0.16 11.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Val_tRNA-synt_C PF10458.9 CBZ32503.1 - 0.12 12.7 0.0 24 5.3 0.0 2.2 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm CLZ PF16526.5 CBZ32503.1 - 0.25 11.7 1.4 8.5 6.8 0.6 2.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SOAR PF16533.5 CBZ32504.1 - 0.016 15.2 1.9 0.06 13.3 1.9 1.9 1 1 0 1 1 1 0 STIM1 Orai1-activating region CENP-Q PF13094.6 CBZ32504.1 - 0.37 11.0 10.1 0.64 10.2 10.1 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit RNase_HII PF01351.18 CBZ32505.1 - 4.3e-14 52.8 0.2 1.4e-11 44.6 0.2 2.2 1 1 0 1 1 1 1 Ribonuclease HII DUF711 PF05167.12 CBZ32505.1 - 0.046 12.6 0.6 0.13 11.1 0.1 1.9 2 1 0 2 2 2 0 Uncharacterised ACR (DUF711) DNA_pol_A PF00476.20 CBZ32508.1 - 1.3e-33 116.6 0.0 4.9e-33 114.7 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase family A RNase_T PF00929.24 CBZ32508.1 - 4.3e-16 59.9 0.0 1.7e-15 58.0 0.0 2.1 1 0 0 1 1 1 1 Exonuclease Pro_dh PF01619.18 CBZ32508.1 - 0.0043 16.6 0.0 0.013 15.1 0.0 1.8 2 0 0 2 2 2 1 Proline dehydrogenase RNase_H_2 PF13482.6 CBZ32508.1 - 0.0064 16.5 0.0 0.037 14.0 0.0 2.2 2 0 0 2 2 2 1 RNase_H superfamily Peptidase_M32 PF02074.15 CBZ32509.1 - 7.6e-157 523.0 0.0 8.6e-157 522.8 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase SURF1 PF02104.15 CBZ32511.1 - 1.2e-30 107.1 0.4 1.8e-30 106.5 0.0 1.4 2 0 0 2 2 2 1 SURF1 family F_actin_bind PF08919.10 CBZ32512.1 - 0.0063 16.6 0.3 0.01 15.9 0.1 1.6 1 1 0 1 1 1 1 F-actin binding Exc PF07825.11 CBZ32512.1 - 0.012 15.6 0.0 0.071 13.1 0.0 2.0 2 0 0 2 2 2 0 Excisionase-like protein Atg14 PF10186.9 CBZ32512.1 - 0.013 14.7 3.4 0.013 14.6 3.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4472 PF14739.6 CBZ32512.1 - 0.016 16.0 4.8 0.02 15.6 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Troponin PF00992.20 CBZ32512.1 - 0.024 14.9 3.8 0.032 14.5 3.8 1.3 1 0 0 1 1 1 0 Troponin Jnk-SapK_ap_N PF09744.9 CBZ32512.1 - 0.027 14.7 7.1 0.03 14.5 7.1 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc24 PF08286.11 CBZ32512.1 - 0.05 13.8 2.1 0.061 13.6 2.1 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 TMPIT PF07851.13 CBZ32512.1 - 0.081 12.2 2.7 0.089 12.0 2.7 1.0 1 0 0 1 1 1 0 TMPIT-like protein SOGA PF11365.8 CBZ32512.1 - 0.089 13.9 7.6 0.13 13.4 7.0 1.6 1 1 0 1 1 1 0 Protein SOGA YabA PF06156.13 CBZ32512.1 - 0.53 11.0 6.1 1.8 9.3 4.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA betaPIX_CC PF16523.5 CBZ32512.1 - 3.4 7.6 9.2 2.1 8.2 4.1 2.2 1 1 0 2 2 2 0 betaPIX coiled coil Kinesin PF00225.23 CBZ32513.1 - 9.4e-89 297.6 0.0 1.5e-88 297.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ32513.1 - 9.4e-14 51.6 0.0 1.9e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding zf-TRAF PF02176.18 CBZ32513.1 - 2.7e-12 47.2 53.7 9e-07 29.5 8.0 5.6 6 1 1 7 7 7 4 TRAF-type zinc finger AAA_22 PF13401.6 CBZ32513.1 - 0.13 12.5 0.2 0.76 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf_UBZ PF18439.1 CBZ32513.1 - 7.9 6.2 13.8 39 4.0 0.3 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger STG PF15809.5 CBZ32515.1 - 0.071 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Simian taste bud-specific gene product family cNMP_binding PF00027.29 CBZ32516.1 - 8.7e-32 109.1 0.5 2.3e-17 62.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF333 PF03891.15 CBZ32516.1 - 0.069 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF333) LRR_6 PF13516.6 CBZ32516.1 - 0.53 10.5 1.9 16 5.9 0.2 2.6 2 0 0 2 2 2 0 Leucine Rich repeat MOZ_SAS PF01853.18 CBZ32517.1 - 1.2e-21 77.2 0.0 1.8e-12 47.3 0.0 2.3 2 0 0 2 2 2 2 MOZ/SAS family zf-MYST PF17772.1 CBZ32517.1 - 0.00079 19.0 3.0 0.002 17.7 3.0 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain DUF1180 PF06679.12 CBZ32517.1 - 0.68 10.3 10.4 0.094 13.1 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) TPR_12 PF13424.6 CBZ32518.1 - 6.3e-14 52.0 14.9 5.5e-08 33.0 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ32518.1 - 2.2e-05 24.2 6.6 0.24 11.6 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ32518.1 - 0.0033 17.2 13.2 1.3 9.0 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ32518.1 - 0.025 15.2 3.5 13 6.7 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ32518.1 - 0.038 13.8 1.6 4.5 7.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ32518.1 - 2.4 8.9 12.8 3.3 8.4 0.1 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat Lipase_3 PF01764.25 CBZ32520.1 - 5.8e-14 52.2 0.0 9.7e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 CBZ32520.1 - 0.22 11.5 0.0 0.36 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_3 PF01764.25 CBZ32521.1 - 1e-13 51.4 0.0 1.9e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF5021 PF16424.5 CBZ32521.1 - 0.035 14.0 0.6 0.061 13.2 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5021) UPF0227 PF05728.12 CBZ32521.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.7 CBZ32521.1 - 0.24 12.0 5.4 0.076 13.6 1.6 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Ras PF00071.22 CBZ32522.1 - 7.6e-53 178.4 0.2 9.1e-53 178.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ32522.1 - 5.1e-36 123.5 0.0 7.3e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ32522.1 - 2.6e-13 49.8 0.0 3.5e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ32522.1 - 7.8e-08 32.0 0.0 9.6e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBZ32522.1 - 3.2e-06 27.2 0.6 0.0024 17.8 0.2 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CBZ32522.1 - 8.7e-06 25.8 0.0 1.4e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CBZ32522.1 - 1.6e-05 25.3 0.0 2.1e-05 24.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ32522.1 - 0.0016 18.7 0.0 0.0029 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CBZ32522.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TsaE PF02367.17 CBZ32522.1 - 0.0022 18.0 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBZ32522.1 - 0.0041 16.6 0.1 0.0069 15.9 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 CBZ32522.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.27 CBZ32522.1 - 0.011 15.3 0.0 0.09 12.3 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBZ32522.1 - 0.021 14.3 0.0 0.027 13.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Rad17 PF03215.15 CBZ32522.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 CBZ32522.1 - 0.023 14.4 0.0 0.045 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBZ32522.1 - 0.027 14.9 0.0 0.05 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase G-alpha PF00503.20 CBZ32522.1 - 0.028 13.6 0.6 0.14 11.3 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.6 CBZ32522.1 - 0.032 14.4 0.0 0.05 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.18 CBZ32522.1 - 0.039 13.5 0.0 0.29 10.7 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF815 PF05673.13 CBZ32522.1 - 0.044 12.9 0.2 0.077 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DAP3 PF10236.9 CBZ32522.1 - 0.045 12.9 0.1 0.081 12.1 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Sigma54_activat PF00158.26 CBZ32522.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain VirE PF05272.11 CBZ32522.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E ABC_tran PF00005.27 CBZ32522.1 - 0.083 13.4 0.1 0.18 12.4 0.1 1.5 1 0 0 1 1 1 0 ABC transporter Septin PF00735.18 CBZ32522.1 - 0.087 12.1 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_18 PF13238.6 CBZ32522.1 - 0.099 13.2 0.1 0.13 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 CBZ32522.1 - 0.11 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Torsin Pox_A32 PF04665.12 CBZ32522.1 - 0.17 11.3 0.0 0.79 9.1 0.1 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein zf-C3HC4_3 PF13920.6 CBZ32523.1 - 6.1e-06 26.0 9.4 1.3e-05 25.0 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ32523.1 - 1.2e-05 25.1 9.3 2.6e-05 24.1 9.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ERM PF00769.19 CBZ32523.1 - 0.00049 20.0 3.7 0.00071 19.5 3.7 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Prok-RING_4 PF14447.6 CBZ32523.1 - 0.0012 18.7 10.5 0.0022 17.8 10.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBZ32523.1 - 0.0095 15.8 9.6 0.02 14.7 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CENP-F_leu_zip PF10473.9 CBZ32523.1 - 0.017 15.2 0.9 0.024 14.7 0.9 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4 PF00097.25 CBZ32523.1 - 0.017 14.9 9.0 0.034 14.0 9.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ32523.1 - 0.027 14.8 10.6 0.049 14.0 10.6 1.5 1 0 0 1 1 1 0 Ring finger domain HIP1_clath_bdg PF16515.5 CBZ32523.1 - 0.029 15.0 5.5 0.029 15.0 5.5 1.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1848 PF08902.11 CBZ32523.1 - 0.055 13.2 0.3 0.077 12.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Allexi_40kDa PF05549.11 CBZ32523.1 - 0.058 12.9 2.5 0.089 12.3 2.5 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein TerB_C PF15615.6 CBZ32523.1 - 0.077 13.3 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 TerB-C domain AATF-Che1 PF13339.6 CBZ32523.1 - 0.081 13.6 1.0 0.14 12.8 1.0 1.3 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Mod_r PF07200.13 CBZ32523.1 - 0.088 12.9 2.4 0.13 12.4 2.4 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein zf-P11 PF03854.14 CBZ32523.1 - 0.12 12.1 8.9 0.22 11.2 8.9 1.4 1 0 0 1 1 1 0 P-11 zinc finger Tho2 PF11262.8 CBZ32523.1 - 0.24 10.5 1.6 0.34 10.1 1.6 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 zf-RING_4 PF14570.6 CBZ32523.1 - 0.25 11.2 9.0 0.44 10.4 9.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4164 PF13747.6 CBZ32523.1 - 0.27 11.6 4.0 0.42 10.9 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF3839 PF12943.7 CBZ32523.1 - 0.34 10.3 0.6 0.48 9.8 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) ADIP PF11559.8 CBZ32523.1 - 0.45 10.6 6.0 0.67 10.0 6.0 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF5327 PF17261.2 CBZ32523.1 - 0.58 10.9 4.0 1.6 9.5 4.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5327) zf-RING_UBOX PF13445.6 CBZ32523.1 - 1 9.5 7.5 2.4 8.2 4.3 2.5 1 1 1 2 2 2 0 RING-type zinc-finger KOG2701 PF09762.9 CBZ32523.1 - 1.3 9.2 4.6 2.7 8.2 4.6 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) 7tm_7 PF08395.12 CBZ32523.1 - 1.4 8.1 3.4 2 7.5 3.4 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor zf-RING_6 PF14835.6 CBZ32523.1 - 1.7 8.6 8.0 1.2 9.0 5.0 2.3 2 1 0 2 2 2 0 zf-RING of BARD1-type protein DUF3138 PF11336.8 CBZ32523.1 - 1.9 7.0 4.1 3 6.4 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ZapB PF06005.12 CBZ32523.1 - 6.4 7.3 8.7 2.9 8.4 3.3 2.2 1 1 1 2 2 2 0 Cell division protein ZapB zinc-ribbons_6 PF07191.12 CBZ32523.1 - 9 6.4 12.8 0.47 10.5 6.6 1.9 2 0 0 2 2 2 0 zinc-ribbons DUF4200 PF13863.6 CBZ32524.1 - 1.2e-24 87.0 25.3 1.2e-24 87.0 25.3 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF4200) Mito_morph_reg PF14972.6 CBZ32524.1 - 0.053 13.1 0.5 0.093 12.3 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial morphogenesis regulator DUF3918 PF13056.6 CBZ32524.1 - 0.055 13.1 0.2 0.18 11.5 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) TACC_C PF05010.14 CBZ32524.1 - 0.06 13.1 36.5 0.072 12.9 30.0 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HTH_26 PF13443.6 CBZ32524.1 - 0.08 13.4 2.5 0.47 10.9 0.7 2.6 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain EMP24_GP25L PF01105.24 CBZ32524.1 - 5.7 6.8 15.2 2.2 8.2 2.4 3.0 3 0 0 3 3 3 0 emp24/gp25L/p24 family/GOLD ANAPC4_WD40 PF12894.7 CBZ32525.1 - 0.017 15.4 0.0 0.73 10.2 0.0 3.1 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Acetyltransf_1 PF00583.25 CBZ32526.1 - 8.2e-15 55.1 0.0 1.5e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBZ32526.1 - 4.2e-07 30.0 0.1 8.1e-07 29.0 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBZ32526.1 - 4.3e-07 29.8 0.0 7.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CBZ32526.1 - 9.7e-06 25.9 0.1 1.9e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CBZ32526.1 - 0.0089 16.2 0.2 0.013 15.6 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CBZ32526.1 - 0.022 14.3 0.1 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase DUF5596 PF18082.1 CBZ32526.1 - 0.036 13.9 0.0 0.087 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5596) Acetyltransf_9 PF13527.7 CBZ32526.1 - 0.048 13.7 0.1 0.048 13.7 0.1 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Alba PF01918.21 CBZ32527.1 - 1e-15 57.3 0.4 1e-15 57.3 0.4 1.5 2 0 0 2 2 2 1 Alba Rpp20 PF12328.8 CBZ32527.1 - 0.00038 20.4 1.6 0.00043 20.2 1.6 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Pkinase PF00069.25 CBZ32528.1 - 4.5e-80 268.8 0.0 7.7e-80 268.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32528.1 - 1.7e-45 155.4 0.0 3.3e-45 154.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.6 CBZ32528.1 - 9.6e-11 42.0 3.7 0.00013 22.4 0.1 5.1 4 1 1 5 5 5 3 HEAT-like repeat Arm PF00514.23 CBZ32528.1 - 6.2e-10 38.8 5.7 0.00022 21.1 0.0 6.2 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CBZ32528.1 - 9.7e-07 29.1 0.0 4e-05 23.9 0.1 3.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 CBZ32528.1 - 3e-06 27.0 2.5 1.6 9.2 0.0 5.4 5 0 0 5 5 4 1 HEAT repeat Kinase-like PF14531.6 CBZ32528.1 - 8.9e-06 25.2 0.0 0.00013 21.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ32528.1 - 9.6e-05 21.3 0.0 0.00017 20.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBZ32528.1 - 0.00013 21.7 1.1 0.0021 17.7 0.1 2.3 1 1 0 2 2 2 1 RIO1 family FTA2 PF13095.6 CBZ32528.1 - 0.0017 18.0 1.2 0.33 10.5 0.1 2.4 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CBZ32528.1 - 0.0039 16.2 0.1 0.007 15.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain DUF3361 PF11841.8 CBZ32528.1 - 0.0042 17.0 0.0 3.5 7.6 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) YrbL-PhoP_reg PF10707.9 CBZ32528.1 - 0.0042 16.6 0.2 0.0088 15.6 0.2 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 CBZ32528.1 - 0.0078 16.2 0.0 0.027 14.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ32528.1 - 0.0095 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CBZ32528.1 - 0.014 14.4 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 ABC1 PF03109.16 CBZ32528.1 - 0.029 14.6 0.1 0.21 11.7 0.0 2.2 1 1 1 2 2 2 0 ABC1 family Cnd1 PF12717.7 CBZ32528.1 - 0.034 14.2 0.7 0.89 9.6 0.0 3.2 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 WAPL PF07814.13 CBZ32528.1 - 0.057 12.2 0.3 0.64 8.7 0.3 2.4 1 1 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin PIP49_C PF12260.8 CBZ32528.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Urb2 PF10441.9 CBZ32528.1 - 0.13 12.2 0.1 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 Urb2/Npa2 family YmcE_antitoxin PF15939.5 CBZ32528.1 - 0.14 12.3 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system Radial_spoke PF04712.12 CBZ32529.1 - 2.1e-118 396.4 22.9 3.6e-86 290.1 8.4 2.5 1 1 1 2 2 2 2 Radial spokehead-like protein AMP-binding PF00501.28 CBZ32530.1 - 6.1e-59 199.7 0.2 9e-59 199.1 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBZ32530.1 - 6.6e-05 23.8 0.5 0.00076 20.4 0.5 2.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain FeoA PF04023.14 CBZ32530.1 - 0.038 14.2 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 FeoA domain Nipped-B_C PF12830.7 CBZ32532.1 - 2.4e-25 89.6 0.0 9.7e-25 87.6 0.0 2.1 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus PIN_9 PF18477.1 CBZ32532.1 - 0.031 14.6 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 PIN like domain NODP PF07684.12 CBZ32532.1 - 0.19 11.9 2.4 0.18 12.0 0.1 2.2 2 0 0 2 2 2 0 NOTCH protein XRCC4 PF06632.12 CBZ32532.1 - 4 6.2 5.9 6.5 5.5 5.9 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Tubulin PF00091.25 CBZ32533.1 - 1.8e-65 220.8 0.0 2.5e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ32533.1 - 4e-50 169.2 0.0 6.7e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CBZ32533.1 - 0.0071 16.0 0.0 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain C2 PF00168.30 CBZ32535.1 - 8.6e-05 22.8 0.0 0.0008 19.7 0.0 2.3 2 0 0 2 2 2 1 C2 domain TMF_TATA_bd PF12325.8 CBZ32537.1 - 2e-07 31.2 58.3 3.9e-06 27.1 2.0 5.6 3 1 2 5 5 5 2 TATA element modulatory factor 1 TATA binding Tektin PF03148.14 CBZ32537.1 - 1.5e-05 24.0 18.5 1.5e-05 24.0 18.5 4.1 2 1 2 5 5 5 1 Tektin family Filament PF00038.21 CBZ32537.1 - 2.5e-05 24.0 54.3 0.011 15.4 16.8 5.1 2 1 4 6 6 6 4 Intermediate filament protein CENP-F_leu_zip PF10473.9 CBZ32537.1 - 4.8e-05 23.4 54.6 1.3 9.0 8.8 6.0 3 1 1 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.9 CBZ32537.1 - 0.00037 20.0 44.9 0.21 10.9 11.0 4.2 2 1 2 4 4 4 2 Uncharacterized coiled-coil protein (DUF2353) SHE3 PF17078.5 CBZ32537.1 - 0.00085 19.1 10.9 0.00085 19.1 10.9 3.8 2 1 2 4 4 4 1 SWI5-dependent HO expression protein 3 GAS PF13851.6 CBZ32537.1 - 0.0027 17.1 54.4 0.15 11.4 1.7 4.7 2 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 CBZ32537.1 - 0.0033 16.4 22.1 0.0033 16.4 22.1 3.9 2 1 3 5 5 5 1 Spc7 kinetochore protein FlaC_arch PF05377.11 CBZ32537.1 - 0.0047 17.3 31.5 1.8 9.0 0.1 8.1 5 3 1 7 7 7 1 Flagella accessory protein C (FlaC) BST2 PF16716.5 CBZ32537.1 - 0.0065 17.0 2.7 0.0065 17.0 2.7 6.9 3 2 3 7 7 7 1 Bone marrow stromal antigen 2 Uso1_p115_C PF04871.13 CBZ32537.1 - 0.012 16.0 61.8 0.13 12.6 1.6 5.8 2 1 4 6 6 6 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF5082 PF16888.5 CBZ32537.1 - 0.013 15.8 4.7 0.013 15.8 4.7 5.9 1 1 2 4 4 3 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 CBZ32537.1 - 0.02 14.9 28.7 1.7 8.7 1.2 5.2 2 1 3 6 6 6 0 Protein of unknown function (DUF1664) Cnn_1N PF07989.11 CBZ32537.1 - 0.022 14.9 6.4 0.022 14.9 6.4 6.4 3 2 3 6 6 5 0 Centrosomin N-terminal motif 1 Wtap PF17098.5 CBZ32537.1 - 0.027 14.4 1.8 0.027 14.4 1.8 7.0 3 2 2 6 6 5 0 WTAP/Mum2p family DivIC PF04977.15 CBZ32537.1 - 0.034 13.9 0.8 0.034 13.9 0.8 8.4 2 2 4 8 8 8 0 Septum formation initiator ATG16 PF08614.11 CBZ32537.1 - 0.04 14.2 69.0 0.14 12.3 19.3 5.5 2 1 4 6 6 6 0 Autophagy protein 16 (ATG16) Rootletin PF15035.6 CBZ32537.1 - 0.055 13.5 60.9 0.074 13.1 11.3 5.8 1 1 4 5 5 5 0 Ciliary rootlet component, centrosome cohesion Fib_alpha PF08702.10 CBZ32537.1 - 0.076 13.2 36.2 1.8 8.7 6.6 4.7 2 1 3 5 5 4 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CBZ32537.1 - 0.088 12.8 25.4 0.21 11.7 1.7 4.2 1 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus UCH_C PF18031.1 CBZ32537.1 - 0.18 11.7 0.1 0.18 11.7 0.1 3.4 3 0 0 3 3 2 0 Ubiquitin carboxyl-terminal hydrolases FAA_hydrolase_N PF09298.11 CBZ32537.1 - 0.19 11.9 0.0 0.19 11.9 0.0 4.1 2 1 2 5 5 4 0 Fumarylacetoacetase N-terminal PLAC9 PF15205.6 CBZ32537.1 - 0.2 12.1 0.5 3.4 8.1 0.0 3.1 3 0 0 3 3 2 0 Placenta-specific protein 9 Fez1 PF06818.15 CBZ32537.1 - 0.32 11.4 51.1 7.1 7.0 1.0 4.3 1 1 5 6 6 6 0 Fez1 THP2 PF09432.10 CBZ32537.1 - 0.4 10.8 18.8 0.9 9.6 1.5 3.7 4 0 0 4 4 3 0 Tho complex subunit THP2 BCL_N PF04714.13 CBZ32537.1 - 0.42 10.7 10.6 17 5.5 0.0 3.7 3 0 0 3 3 3 0 BCL7, N-terminal conserver region Myosin_tail_1 PF01576.19 CBZ32537.1 - 0.65 7.7 53.6 0.029 12.2 45.7 2.0 2 0 0 2 2 2 0 Myosin tail NPV_P10 PF05531.12 CBZ32537.1 - 0.97 9.9 23.8 3.3 8.2 2.4 5.6 4 2 1 5 5 4 0 Nucleopolyhedrovirus P10 protein TSC22 PF01166.18 CBZ32537.1 - 1.2 9.5 31.6 10 6.5 0.9 7.1 4 2 2 6 6 6 0 TSC-22/dip/bun family DUF4407 PF14362.6 CBZ32537.1 - 1.5 8.1 47.8 32 3.8 13.4 3.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Leu_zip PF15294.6 CBZ32537.1 - 1.7 8.1 40.2 0.89 9.0 5.2 3.9 2 1 2 4 4 4 0 Leucine zipper TPR_MLP1_2 PF07926.12 CBZ32537.1 - 2 8.5 71.5 0.05 13.7 14.5 6.8 3 2 1 5 5 5 0 TPR/MLP1/MLP2-like protein DUF4988 PF16378.5 CBZ32537.1 - 2.4 7.8 11.2 16 5.1 0.4 4.5 3 2 1 4 4 4 0 Domain of unknown function Seryl_tRNA_N PF02403.22 CBZ32537.1 - 2.7 8.2 42.8 0.87 9.8 6.7 6.1 3 2 4 7 7 7 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 CBZ32537.1 - 3.3 6.2 34.3 1.6 7.2 7.1 4.5 2 1 3 5 5 5 0 Flagellar Assembly Protein A CALCOCO1 PF07888.11 CBZ32537.1 - 3.9 6.2 57.4 3.4 6.4 45.4 3.0 2 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2703 PF10865.8 CBZ32537.1 - 4.2 7.6 7.9 1.1 9.5 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2703) ZapB PF06005.12 CBZ32537.1 - 5.8 7.4 68.2 3 8.4 0.4 7.4 2 1 5 7 7 7 0 Cell division protein ZapB EzrA PF06160.12 CBZ32537.1 - 7.2 4.6 38.7 2.7 6.1 3.5 4.0 2 1 0 3 3 3 0 Septation ring formation regulator, EzrA TMF_DNA_bd PF12329.8 CBZ32537.1 - 7.9 6.6 55.6 0.24 11.4 2.4 8.4 4 3 3 8 8 8 0 TATA element modulatory factor 1 DNA binding DUF1045 PF06299.12 CBZ32537.1 - 9.7 6.1 13.6 0.9 9.5 0.7 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1045) His_Phos_1 PF00300.22 CBZ32538.1 - 2e-07 30.9 0.0 8.9e-05 22.3 0.0 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Sec63 PF02889.16 CBZ32539.1 - 1.3e-142 473.4 2.5 1.6e-80 270.0 0.8 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CBZ32539.1 - 7.9e-52 175.6 0.0 3.2e-27 95.4 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CBZ32539.1 - 8.5e-28 97.5 0.0 9.7e-16 58.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ32539.1 - 3.5e-16 59.5 0.0 2.7e-07 30.9 0.0 4.0 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 CBZ32539.1 - 2.5e-09 37.1 0.0 0.00034 20.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CBZ32539.1 - 8.7e-07 29.4 0.6 0.0015 18.8 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 CBZ32539.1 - 1.4e-05 25.4 0.1 0.013 15.8 0.0 3.7 2 2 0 2 2 2 1 AAA domain T2SSE PF00437.20 CBZ32539.1 - 0.0016 17.6 0.0 2 7.4 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein SWI2_SNF2 PF18766.1 CBZ32539.1 - 0.0019 17.9 0.1 0.15 11.7 0.1 2.3 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 CBZ32539.1 - 0.007 15.6 0.0 0.018 14.3 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CBZ32539.1 - 0.016 14.6 0.1 0.35 10.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 CBZ32539.1 - 0.052 13.1 0.2 4.2 6.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Ccdc124 PF06244.12 CBZ32541.1 - 2.4e-25 89.5 18.4 1.8e-24 86.7 18.4 2.2 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 CBZ32541.1 - 0.021 15.3 0.4 0.021 15.3 0.4 2.8 2 1 1 3 3 3 0 HMG (high mobility group) box F-protein PF00469.20 CBZ32541.1 - 0.14 11.7 6.3 0.28 10.8 6.3 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef DUF3435 PF11917.8 CBZ32541.1 - 0.31 9.9 10.7 0.45 9.4 10.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF3807 PF12720.7 CBZ32541.1 - 1.2 9.4 16.0 2.9 8.1 16.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Selenoprotein_S PF06936.11 CBZ32541.1 - 4.5 7.0 17.2 15 5.4 16.0 2.4 2 1 1 3 3 3 0 Selenoprotein S (SelS) DUF3464 PF11947.8 CBZ32541.1 - 5.2 6.8 10.0 11 5.8 10.0 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 HAD_SAK_2 PF18143.1 CBZ32542.1 - 0.17 12.2 2.8 0.23 11.7 0.6 2.5 2 0 0 2 2 2 0 HAD domain in Swiss Army Knife RNA repair proteins DUF3169 PF11368.8 CBZ32543.1 - 0.23 10.9 0.0 0.34 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF179 PF02622.15 CBZ32544.1 - 4.6e-19 68.9 0.0 8.6e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 Ribosomal_L7Ae PF01248.26 CBZ32545.1 - 1.9e-22 78.8 1.4 2.5e-22 78.4 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MCU PF04678.13 CBZ32548.1 - 1.7e-12 47.8 0.8 2.5e-12 47.2 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial calcium uniporter RCDG1 PF15725.5 CBZ32548.1 - 0.066 13.6 1.1 0.066 13.6 1.1 2.2 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein DUF1192 PF06698.11 CBZ32548.1 - 0.19 11.8 1.6 0.36 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Acetyltransf_10 PF13673.7 CBZ32549.1 - 1.6e-05 24.8 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ32549.1 - 0.00012 22.2 0.0 0.00019 21.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBZ32549.1 - 0.0036 17.7 0.0 0.0066 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2408 PF10303.9 CBZ32550.1 - 0.042 14.4 1.1 0.073 13.6 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF724 PF05266.14 CBZ32550.1 - 0.18 11.6 2.5 0.28 11.0 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 CBZ32550.1 - 0.67 10.0 3.4 1.3 9.1 3.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NAD_binding_7 PF13241.6 CBZ32550.1 - 0.89 10.0 5.7 13 6.2 1.3 2.3 1 1 1 2 2 2 0 Putative NAD(P)-binding DUF4061 PF13270.6 CBZ32551.1 - 0.025 14.9 0.1 0.061 13.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Cse1 PF08506.10 CBZ32552.1 - 0.0082 15.0 0.0 0.022 13.6 0.0 1.6 1 0 0 1 1 1 1 Cse1 HEAT_EZ PF13513.6 CBZ32552.1 - 0.01 16.3 0.5 0.01 16.3 0.5 3.8 4 0 0 4 4 4 0 HEAT-like repeat Xpo1 PF08389.12 CBZ32552.1 - 0.038 14.1 0.1 0.35 10.9 0.0 2.5 2 0 0 2 2 2 0 Exportin 1-like protein HEAT PF02985.22 CBZ32552.1 - 0.056 13.7 1.2 0.88 10.0 0.5 3.6 2 0 0 2 2 2 0 HEAT repeat SDA1 PF05285.12 CBZ32552.1 - 0.12 11.8 9.7 0.18 11.2 9.7 1.2 1 0 0 1 1 1 0 SDA1 DHHC PF01529.20 CBZ32553.1 - 8.1e-26 90.7 13.4 8.1e-26 90.7 13.4 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase HemY_N PF07219.13 CBZ32553.1 - 0.026 14.7 3.6 1.8 8.8 0.5 3.3 3 0 0 3 3 3 0 HemY protein N-terminus U-box PF04564.15 CBZ32554.1 - 2.2e-06 27.8 0.0 4.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain Lectin_leg-like PF03388.13 CBZ32555.1 - 2.7e-47 161.1 0.0 4e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CBZ32555.1 - 9.2e-11 42.1 0.0 2.2e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial lectin Adaptin_binding PF10199.9 CBZ32555.1 - 0.0005 20.7 1.6 0.0008 20.0 1.6 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 TFIIA PF03153.13 CBZ32555.1 - 0.06 13.3 14.8 0.075 13.0 14.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_A_type_inc PF04508.12 CBZ32555.1 - 1.9 8.5 7.2 4.1 7.4 7.2 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Dicty_REP PF05086.12 CBZ32555.1 - 2 6.3 6.3 2.5 6.0 6.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_M24 PF00557.24 CBZ32556.1 - 1.3e-13 51.2 1.0 2.9e-12 46.7 0.6 2.6 2 1 1 3 3 3 2 Metallopeptidase family M24 PSP1 PF04468.12 CBZ32557.1 - 1.6e-20 73.1 0.0 3.3e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region TMEM215 PF15746.5 CBZ32557.1 - 0.34 10.3 1.8 0.72 9.3 0.3 2.3 1 1 1 2 2 2 0 TMEM215 family Kinesin PF00225.23 CBZ32558.1 - 5.4e-32 111.0 0.0 3.7e-06 26.1 0.0 5.2 5 0 0 5 5 5 5 Kinesin motor domain Microtub_bd PF16796.5 CBZ32558.1 - 6.6e-06 26.1 0.0 7.6e-05 22.7 0.0 2.3 2 1 0 2 2 2 1 Microtubule binding ArfGap PF01412.18 CBZ32559.1 - 2.2e-29 101.9 0.1 3.8e-29 101.2 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ADH_zinc_N PF00107.26 CBZ32560.1 - 1.2e-12 48.0 0.0 2.3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ32560.1 - 3.9e-11 42.8 0.0 1.1e-10 41.3 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CBZ32560.1 - 1.7e-07 32.4 0.0 3.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ubiquitin PF00240.23 CBZ32561.1 - 2e-10 40.3 0.0 5e-10 39.0 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CBZ32561.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBZ32561.1 - 0.00083 19.9 0.0 0.0033 17.9 0.0 2.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBZ32561.1 - 0.0025 17.9 0.0 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBZ32561.1 - 0.1 13.1 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Anoctamin PF04547.12 CBZ32562.1 - 2.1e-78 264.2 0.0 2.6e-78 263.9 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel C2 PF00168.30 CBZ32564.1 - 1.5e-20 73.4 0.0 2.8e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain DSPc PF00782.20 CBZ32565.1 - 2.1e-07 30.8 0.1 4.1e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Pkinase PF00069.25 CBZ32566.1 - 1.8e-39 135.7 0.0 2e-33 115.9 0.0 3.1 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32566.1 - 1.4e-15 57.3 0.0 1.8e-14 53.6 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ32566.1 - 0.00028 20.3 0.0 0.00059 19.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like CTU2 PF10288.9 CBZ32567.1 - 0.0013 18.9 0.3 0.0013 18.9 0.3 2.2 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 CBZ32567.1 - 0.021 14.6 0.3 0.5 10.1 0.0 2.7 3 0 0 3 3 3 0 PP-loop family CDRN PF05174.12 CBZ32567.1 - 0.031 14.0 0.4 0.14 11.9 0.1 2.4 2 0 0 2 2 2 0 Cysteine-rich D. radiodurans N terminus NUDE_C PF04880.13 CBZ32568.1 - 0.12 12.9 9.1 0.22 12.0 9.1 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Complex1_LYR_2 PF13233.6 CBZ32570.1 - 2.3e-07 31.5 0.0 4.4e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CBZ32570.1 - 0.056 13.5 2.8 4.7 7.4 0.0 2.8 3 0 0 3 3 3 0 Complex 1 protein (LYR family) Serine_rich PF08824.10 CBZ32571.1 - 1.5 8.8 6.5 0.12 12.4 1.0 2.0 2 0 0 2 2 2 0 Serine rich protein interaction domain Peptidase_M16 PF00675.20 CBZ32575.1 - 0.0001 22.3 0.3 0.002 18.1 0.0 2.5 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBZ32575.1 - 0.00037 20.6 0.0 0.00098 19.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF3381 PF11861.8 CBZ32576.1 - 0.72 9.6 0.0 0.72 9.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3381) YebO PF13974.6 CBZ32576.1 - 2.5 8.3 0.0 2.5 8.3 0.0 4.3 4 1 0 4 4 4 0 YebO-like protein OEP PF02321.18 CBZ32577.1 - 0.17 11.7 7.1 31 4.3 0.0 2.2 2 0 0 2 2 2 0 Outer membrane efflux protein DUF3246 PF11596.8 CBZ32578.1 - 1.7 8.0 7.3 4.4 6.7 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) LRR_6 PF13516.6 CBZ32579.1 - 4.7e-05 23.1 0.4 0.78 9.9 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 CBZ32579.1 - 0.02 14.7 1.3 0.02 14.7 1.3 2.2 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 CBZ32579.1 - 0.07 13.6 6.6 0.076 13.5 3.9 2.4 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ32579.1 - 0.26 12.0 4.8 4.4 8.2 0.5 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat Ax_dynein_light PF10211.9 CBZ32580.1 - 0.0002 21.4 5.4 0.0002 21.4 5.4 2.1 2 0 0 2 2 2 1 Axonemal dynein light chain DUF4201 PF13870.6 CBZ32580.1 - 0.022 14.5 5.9 0.052 13.3 5.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF4727 PF15856.5 CBZ32580.1 - 0.027 14.1 3.0 0.72 9.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4727) GvpG PF05120.12 CBZ32580.1 - 0.047 13.7 3.3 0.16 12.0 3.3 1.9 1 0 0 1 1 1 0 Gas vesicle protein G Cluap1 PF10234.9 CBZ32580.1 - 0.084 12.3 5.5 0.22 10.9 5.5 1.7 1 0 0 1 1 1 0 Clusterin-associated protein-1 PXA PF02194.15 CBZ32580.1 - 0.38 10.7 4.4 1.1 9.2 4.4 1.8 1 0 0 1 1 1 0 PXA domain Prominin PF05478.11 CBZ32580.1 - 0.68 7.8 3.9 1.1 7.1 3.9 1.2 1 0 0 1 1 1 0 Prominin APG6_N PF17675.1 CBZ32580.1 - 0.78 10.3 16.4 0.046 14.2 7.5 2.8 2 0 0 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 CBZ32580.1 - 1.2 9.4 12.3 0.038 14.2 3.3 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GIT_CC PF16559.5 CBZ32580.1 - 1.9 8.4 4.8 7 6.6 4.8 2.0 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 CBZ32580.1 - 3.7 7.6 5.1 1.7 8.7 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cob_adeno_trans PF01923.18 CBZ32580.1 - 6.5 6.9 9.1 0.76 9.9 3.0 2.5 3 0 0 3 3 3 0 Cobalamin adenosyltransferase Glyco_transf_25 PF01755.17 CBZ32581.1 - 3e-19 69.7 0.0 1.4e-18 67.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 25 (LPS biosynthesis protein) TRM PF02005.16 CBZ32582.1 - 8.9e-95 318.0 0.0 2.9e-44 151.8 0.1 3.1 3 0 0 3 3 3 3 N2,N2-dimethylguanosine tRNA methyltransferase DNA_pol_E_B PF04042.16 CBZ32582.1 - 0.14 11.4 0.0 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B FYDLN_acid PF09538.10 CBZ32582.1 - 9.8 6.9 7.3 2.1 9.1 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Actin PF00022.19 CBZ32583.1 - 1.1e-114 383.3 0.0 1.2e-112 376.5 0.0 2.7 1 1 0 1 1 1 1 Actin AAA PF00004.29 CBZ32584.1 - 4.5e-37 127.4 0.0 8.6e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ32584.1 - 2e-08 33.9 0.4 4.7e-08 32.7 0.4 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CBZ32584.1 - 2.8e-07 30.4 0.0 7.8e-07 29.0 0.0 1.7 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 CBZ32584.1 - 5.4e-06 26.7 2.6 0.028 14.7 0.1 3.3 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.12 CBZ32584.1 - 2e-05 24.4 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ32584.1 - 0.00037 20.9 0.0 0.0012 19.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CBZ32584.1 - 0.0004 20.2 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain LisH_TPL PF17814.1 CBZ32584.1 - 0.00043 19.9 0.7 0.00095 18.8 0.7 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain TIP49 PF06068.13 CBZ32584.1 - 0.0011 18.2 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 CBZ32584.1 - 0.0017 17.9 0.2 0.12 11.9 0.2 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBZ32584.1 - 0.0044 16.8 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CBZ32584.1 - 0.0065 17.0 0.0 0.021 15.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 CBZ32584.1 - 0.0076 16.2 0.0 0.022 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBZ32584.1 - 0.012 15.7 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CBZ32584.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CBZ32584.1 - 0.019 14.5 0.0 0.055 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 CBZ32584.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CBZ32584.1 - 0.03 13.7 0.1 0.73 9.1 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 CBZ32584.1 - 0.037 14.4 0.0 0.078 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 CBZ32584.1 - 0.047 13.1 0.2 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein LisH PF08513.11 CBZ32584.1 - 0.053 13.5 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 LisH AAA_28 PF13521.6 CBZ32584.1 - 0.072 13.3 0.2 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ32584.1 - 0.078 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mesothelin PF06060.12 CBZ32584.1 - 0.16 10.1 0.0 0.26 9.4 0.0 1.2 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) K-cyclin_vir_C PF09080.10 CBZ32585.1 - 0.05 14.0 3.5 9.1 6.8 0.0 3.1 3 0 0 3 3 3 0 K cyclin, C terminal DNA_gyraseA_C PF03989.13 CBZ32585.1 - 0.26 10.8 0.7 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller A_deaminase PF00962.22 CBZ32586.1 - 3e-86 289.7 0.0 5.1e-80 269.3 0.0 3.2 3 1 0 3 3 3 2 Adenosine/AMP deaminase Kinocilin PF15033.6 CBZ32589.1 - 0.11 12.1 3.3 1.6 8.4 1.7 2.4 2 0 0 2 2 2 0 Kinocilin protein CAP59_mtransfer PF11735.8 CBZ32590.1 - 1.4e-54 185.4 0.0 2.2e-53 181.4 0.0 2.3 2 0 0 2 2 2 1 Cryptococcal mannosyltransferase 1 DUF885 PF05960.11 CBZ32590.1 - 0.025 14.2 0.3 0.093 12.4 0.2 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) Peptidase_S8 PF00082.22 CBZ32592.1 - 1.3e-22 80.5 0.2 3e-22 79.3 0.2 1.6 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 CBZ32593.1 - 1.3e-22 80.5 0.2 3e-22 79.3 0.2 1.6 1 0 0 1 1 1 1 Subtilase family Dpy-30 PF05186.13 CBZ32594.1 - 3.1e-08 33.2 0.5 5.3e-08 32.4 0.5 1.4 1 0 0 1 1 1 1 Dpy-30 motif FeoB_Cyto PF17910.1 CBZ32594.1 - 0.092 13.3 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 FeoB cytosolic helical domain FAD_binding_6 PF00970.24 CBZ32595.1 - 1.1e-29 102.6 0.0 1.6e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBZ32595.1 - 1.1e-28 100.1 0.0 4.7e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CBZ32595.1 - 0.00069 19.8 0.0 0.016 15.4 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain AAA PF00004.29 CBZ32598.1 - 1.6e-42 145.1 0.0 2.8e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ32598.1 - 6.4e-09 35.5 0.5 1.3e-08 34.5 0.5 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CBZ32598.1 - 5.1e-07 29.6 0.1 1e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CBZ32598.1 - 3.2e-06 27.4 0.0 6.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CBZ32598.1 - 5.4e-06 26.4 0.1 2e-05 24.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_OB_N PF17758.1 CBZ32598.1 - 2.3e-05 23.9 0.1 7.5e-05 22.3 0.0 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain AAA_16 PF13191.6 CBZ32598.1 - 3.3e-05 24.3 0.2 0.0032 17.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ32598.1 - 4.5e-05 23.7 0.4 0.023 15.0 0.4 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CBZ32598.1 - 0.00048 19.4 0.0 0.00076 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBZ32598.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBZ32598.1 - 0.0028 18.2 0.0 0.0065 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBZ32598.1 - 0.0057 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CBZ32598.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CBZ32598.1 - 0.025 13.9 0.2 0.31 10.4 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 CBZ32598.1 - 0.025 14.9 0.0 0.071 13.5 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_28 PF13521.6 CBZ32598.1 - 0.034 14.4 0.1 0.084 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 CBZ32598.1 - 0.035 14.1 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBZ32598.1 - 0.048 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBZ32598.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CBZ32598.1 - 0.06 13.1 0.5 0.25 11.0 0.2 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CBZ32598.1 - 0.078 12.2 0.1 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CBZ32598.1 - 0.095 12.6 0.2 0.99 9.3 0.1 2.3 1 1 1 2 2 2 0 NACHT domain TIP49 PF06068.13 CBZ32598.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CBZ32598.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CBZ32598.1 - 0.16 11.2 0.0 0.97 8.6 0.0 2.3 4 0 0 4 4 4 0 NB-ARC domain AAA_25 PF13481.6 CBZ32598.1 - 0.22 11.1 0.8 5.4 6.6 0.3 2.5 1 1 1 2 2 2 0 AAA domain tRNA-synt_1 PF00133.22 CBZ32599.1 - 6.4e-27 94.0 0.0 5.6e-09 34.8 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CBZ32599.1 - 9.6e-20 70.7 0.0 8.8e-10 37.9 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CBZ32599.1 - 8e-12 45.4 0.2 2.3e-11 43.9 0.2 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CBZ32599.1 - 2.5e-07 30.4 0.0 5.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain RNA_pol_N PF01194.17 CBZ32601.1 - 9.6e-25 86.7 1.8 1.2e-24 86.4 1.8 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit DUF155 PF02582.14 CBZ32602.1 - 2.7e-39 135.0 0.0 4.2e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Abhydrolase_6 PF12697.7 CBZ32603.1 - 7.3e-16 59.4 4.1 7.9e-15 56.1 4.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBZ32603.1 - 3.8e-10 39.9 0.0 1.3e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ32603.1 - 4.9e-05 22.7 0.1 0.0023 17.2 0.2 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 CBZ32603.1 - 0.00058 19.6 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Abhydro_lipase PF04083.16 CBZ32603.1 - 0.07 12.7 0.0 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region DUF676 PF05057.14 CBZ32603.1 - 0.19 11.2 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Endonuc-BglII PF09195.11 CBZ32604.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease BglII EF-hand_7 PF13499.6 CBZ32605.1 - 4.1e-15 56.0 0.2 8.5e-07 29.3 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ32605.1 - 2.4e-13 48.6 6.3 7.3e-08 31.4 0.1 3.8 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 CBZ32605.1 - 2.8e-11 43.1 1.7 0.001 18.9 0.0 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CBZ32605.1 - 1.1e-10 40.5 0.2 6.1e-06 25.8 0.0 3.9 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBZ32605.1 - 7.5e-07 28.4 0.2 1.2e-05 24.6 0.2 2.7 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 CBZ32605.1 - 0.00051 20.3 0.0 0.17 12.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CBZ32605.1 - 0.076 13.0 0.0 4.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PNRC PF15365.6 CBZ32605.1 - 0.28 11.0 6.8 0.78 9.6 6.8 1.8 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif DNA_ligase_IV PF11411.8 CBZ32605.1 - 0.57 10.4 3.0 2.7 8.2 0.2 2.9 3 0 0 3 3 3 0 DNA ligase IV MAM33 PF02330.16 CBZ32606.1 - 6.8e-10 39.3 0.1 1.6e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tctex-1 PF03645.13 CBZ32607.1 - 2.1e-23 82.5 0.0 3.3e-23 81.9 0.0 1.3 1 1 0 1 1 1 1 Tctex-1 family Rio2_N PF09202.11 CBZ32607.1 - 0.057 13.6 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 Rio2, N-terminal QueF PF14489.6 CBZ32607.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.5 2 0 0 2 2 2 0 QueF-like protein Adenylsucc_synt PF00709.21 CBZ32608.1 - 7.8e-93 311.7 0.0 1e-92 311.3 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ribosomal_L27 PF01016.19 CBZ32609.1 - 0.12 12.4 0.3 0.24 11.4 0.3 1.6 1 1 0 1 1 1 0 Ribosomal L27 protein Nucleoside_tran PF01733.18 CBZ32610.1 - 1.2e-29 103.7 1.2 7.6e-19 68.2 0.0 2.4 2 0 0 2 2 2 2 Nucleoside transporter Ribosomal_S4e PF00900.20 CBZ32611.1 - 2.7e-24 84.9 0.1 4.8e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.12 CBZ32611.1 - 7.9e-18 64.3 4.7 1.9e-17 63.0 4.7 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain 40S_S4_C PF16121.5 CBZ32611.1 - 1.8e-16 59.5 0.0 3.3e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus S4 PF01479.25 CBZ32611.1 - 5.3e-07 29.2 0.0 1.3e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 CBZ32611.1 - 0.0001 22.1 1.8 0.00011 22.0 0.3 1.9 2 0 0 2 2 2 1 KOW motif TPK_catalytic PF04263.16 CBZ32613.1 - 5.5e-09 36.1 0.0 0.005 16.9 0.0 3.1 3 0 0 3 3 3 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CBZ32613.1 - 5e-07 29.3 0.0 2e-06 27.4 0.0 2.0 2 1 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF624 PF04854.14 CBZ32614.1 - 0.029 14.5 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF624 Comm PF15957.5 CBZ32615.1 - 0.0078 16.5 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 Commissureless TMEM154 PF15102.6 CBZ32615.1 - 0.011 15.7 0.8 0.021 14.7 0.3 1.8 1 1 0 1 1 1 0 TMEM154 protein family PRIMA1 PF16101.5 CBZ32615.1 - 0.011 15.7 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 LRR19-TM PF15176.6 CBZ32615.1 - 0.015 15.3 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain SID-1_RNA_chan PF13965.6 CBZ32615.1 - 0.016 13.7 0.0 0.021 13.3 0.0 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 V_ATPase_I PF01496.19 CBZ32615.1 - 0.019 13.0 0.0 0.02 12.9 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM132D_C PF15706.5 CBZ32615.1 - 0.019 14.7 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF4834 PF16118.5 CBZ32615.1 - 0.028 15.4 0.0 0.043 14.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Chordopox_A13L PF05961.11 CBZ32615.1 - 0.03 14.5 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein EphA2_TM PF14575.6 CBZ32615.1 - 0.034 15.0 0.0 0.055 14.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain STE2 PF02116.15 CBZ32615.1 - 0.044 13.1 0.0 1.2 8.3 0.0 2.0 2 0 0 2 2 2 0 Fungal pheromone mating factor STE2 GPCR DUF4381 PF14316.6 CBZ32615.1 - 0.096 12.9 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Zip PF02535.22 CBZ32615.1 - 0.12 11.6 0.2 0.17 11.1 0.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.16 CBZ32615.1 - 0.54 9.4 2.1 0.68 9.1 2.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Endonuclease_NS PF01223.23 CBZ32616.1 - 4e-17 62.8 0.0 9.9e-17 61.5 0.0 1.5 2 0 0 2 2 2 1 DNA/RNA non-specific endonuclease ACC_epsilon PF13822.6 CBZ32616.1 - 0.0097 16.6 5.5 0.0097 16.6 5.5 4.8 5 0 0 5 5 5 1 Acyl-CoA carboxylase epsilon subunit AT_hook PF02178.19 CBZ32616.1 - 0.59 10.2 4.3 1.6 8.8 4.3 1.8 1 0 0 1 1 1 0 AT hook motif ATP_bind_1 PF03029.17 CBZ32617.1 - 1.9e-60 204.7 0.0 4.6e-58 196.9 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein SRP54 PF00448.22 CBZ32617.1 - 5.7e-06 26.1 0.0 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CBZ32617.1 - 1e-05 26.0 0.1 2.7e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 CBZ32617.1 - 3.2e-05 23.6 0.0 0.024 14.2 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ32617.1 - 8.3e-05 22.6 0.0 0.00017 21.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ32617.1 - 0.00015 21.7 0.0 1.6 8.6 0.0 3.5 4 0 0 4 4 4 2 RsgA GTPase AAA_24 PF13479.6 CBZ32617.1 - 0.00016 21.4 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CBZ32617.1 - 0.00074 18.6 0.7 0.022 13.8 0.1 2.9 2 2 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CBZ32617.1 - 0.0011 18.6 0.9 0.35 10.4 0.1 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CBZ32617.1 - 0.0017 18.1 0.3 0.004 16.9 0.3 1.8 1 1 0 1 1 1 1 AAA domain Arf PF00025.21 CBZ32617.1 - 0.0034 16.9 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_33 PF13671.6 CBZ32617.1 - 0.004 17.3 0.0 0.0069 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CBZ32617.1 - 0.0045 16.9 0.2 0.025 14.5 0.2 2.1 1 1 0 1 1 1 1 NTPase DLIC PF05783.11 CBZ32617.1 - 0.0052 15.7 0.2 0.081 11.7 0.0 2.0 2 0 0 2 2 2 1 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 CBZ32617.1 - 0.0065 16.7 0.0 0.028 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CBZ32617.1 - 0.0075 15.5 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_31 PF13614.6 CBZ32617.1 - 0.0076 16.2 0.0 0.65 9.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBZ32617.1 - 0.0079 16.5 0.5 0.018 15.4 0.5 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBZ32617.1 - 0.013 14.8 0.8 0.025 13.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 CBZ32617.1 - 0.014 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CBZ32617.1 - 0.014 15.3 0.0 0.043 13.7 0.0 1.8 1 0 0 1 1 1 0 NACHT domain SRPRB PF09439.10 CBZ32617.1 - 0.015 14.7 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit 6PF2K PF01591.18 CBZ32617.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Torsin PF06309.11 CBZ32617.1 - 0.024 14.8 0.0 0.042 14.0 0.0 1.3 1 0 0 1 1 1 0 Torsin G-alpha PF00503.20 CBZ32617.1 - 0.024 13.8 0.0 0.74 8.9 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Roc PF08477.13 CBZ32617.1 - 0.043 14.0 0.1 0.4 10.9 0.0 2.3 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ32617.1 - 0.049 13.2 0.4 3.6 7.2 0.0 2.7 3 1 0 3 3 2 0 Ras family Sigma54_activat PF00158.26 CBZ32617.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 CBZ32617.1 - 0.058 13.9 0.1 0.12 12.9 0.1 1.7 2 1 0 2 2 1 0 AAA domain APS_kinase PF01583.20 CBZ32617.1 - 0.061 13.2 0.1 0.14 12.0 0.0 1.6 2 0 0 2 2 1 0 Adenylylsulphate kinase ATPase_2 PF01637.18 CBZ32617.1 - 0.064 13.2 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MobB PF03205.14 CBZ32617.1 - 0.068 13.1 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 CBZ32617.1 - 0.075 12.8 0.1 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 CBZ32617.1 - 0.081 12.1 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain PduV-EutP PF10662.9 CBZ32617.1 - 0.11 12.3 0.1 0.6 9.8 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 CBZ32617.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CLP1_P PF16575.5 CBZ32617.1 - 0.11 12.3 0.0 1.2 8.9 0.0 2.2 1 1 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop CbiA PF01656.23 CBZ32617.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.14 CBZ32617.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Septin PF00735.18 CBZ32617.1 - 0.17 11.2 0.4 1.2 8.4 0.4 2.3 1 1 0 1 1 1 0 Septin AAA_5 PF07728.14 CBZ32617.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TetR_C_15 PF17918.1 CBZ32618.1 - 0.11 13.3 4.9 1.4 9.7 0.0 3.9 3 1 1 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Complex1_LYR_1 PF13232.6 CBZ32619.1 - 9e-41 138.4 2.1 1.4e-40 137.8 2.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CBZ32619.1 - 4.2e-06 26.7 0.1 1.1e-05 25.3 0.1 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4771 PF15995.5 CBZ32619.1 - 0.0018 18.5 0.2 0.0028 17.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4771) DUF5075 PF16825.5 CBZ32620.1 - 4.3e-12 46.1 0.4 9.8e-12 44.9 0.4 1.6 1 0 0 1 1 1 1 IGP family C-type lectin domain DUF3357 PF11837.8 CBZ32620.1 - 0.013 15.9 0.0 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF4576 PF15144.6 CBZ32620.1 - 0.18 11.7 0.0 0.46 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Pox_EPC_I2-L1 PF12575.8 CBZ32620.1 - 2.1 8.7 4.4 1.5 9.1 1.7 2.0 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF5075 PF16825.5 CBZ32621.1 - 1.8e-10 40.8 1.6 3.4e-10 39.9 1.6 1.5 1 1 0 1 1 1 1 IGP family C-type lectin domain Shisa PF13908.6 CBZ32621.1 - 0.00099 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SCIMP PF15050.6 CBZ32621.1 - 0.0039 17.7 0.7 0.0087 16.5 0.3 1.8 2 0 0 2 2 2 1 SCIMP protein SUR7 PF06687.12 CBZ32621.1 - 0.02 14.5 1.4 0.036 13.7 1.4 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF4492 PF14899.6 CBZ32621.1 - 0.034 14.1 2.3 0.069 13.1 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) Ferlin_C PF16165.5 CBZ32621.1 - 0.057 13.4 0.1 0.085 12.8 0.1 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Catalase_C PF18011.1 CBZ32621.1 - 0.085 12.5 0.1 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 C-terminal domain found in long catalases PRIMA1 PF16101.5 CBZ32621.1 - 0.2 11.7 3.4 0.41 10.7 3.4 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 TMIE PF16038.5 CBZ32621.1 - 0.21 11.4 4.4 0.36 10.7 4.4 1.3 1 0 0 1 1 1 0 TMIE protein Rhabdo_glycop PF00974.18 CBZ32621.1 - 0.68 8.3 1.7 1 7.8 1.7 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein TMEM52 PF14979.6 CBZ32621.1 - 1 9.3 3.8 1.9 8.4 3.8 1.4 1 0 0 1 1 1 0 Transmembrane 52 Orthoreo_P10 PF07204.11 CBZ32621.1 - 1.1 9.3 3.2 0.95 9.5 1.8 1.6 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 DUF630 PF04783.12 CBZ32623.1 - 0.018 15.2 0.3 0.069 13.3 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF630) Phage_GP20 PF06810.11 CBZ32623.1 - 3.5 7.4 6.7 0.34 10.7 0.3 2.3 2 1 0 2 2 2 0 Phage minor structural protein GP20 Dpy-30 PF05186.13 CBZ32624.1 - 5.2e-14 51.7 0.5 1.2e-13 50.5 0.5 1.6 1 0 0 1 1 1 1 Dpy-30 motif Hydin_ADK PF17213.3 CBZ32624.1 - 0.00021 21.6 0.0 0.00021 21.6 0.0 2.8 3 0 0 3 3 3 1 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 CBZ32624.1 - 0.032 14.8 0.0 18 5.9 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CBZ32624.1 - 0.07 13.5 0.2 0.07 13.5 0.2 3.6 4 1 0 4 4 4 0 AAA ATPase domain Sin_N PF04801.13 CBZ32626.1 - 2.3e-76 257.7 0.0 3.7e-76 257.1 0.0 1.3 2 0 0 2 2 2 1 Sin-like protein conserved region Botulinum_HA-17 PF05588.11 CBZ32626.1 - 0.2 11.7 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Clostridium botulinum HA-17 domain EMP70 PF02990.16 CBZ32627.1 - 4.7e-110 368.7 20.9 4.7e-110 368.7 20.9 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 Lactamase_B_2 PF12706.7 CBZ32628.1 - 1.1e-31 109.9 2.8 5.1e-19 68.6 0.1 2.2 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CBZ32628.1 - 4.1e-12 46.3 0.1 5.7e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBZ32628.1 - 0.0067 16.5 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily WD40 PF00400.32 CBZ32629.1 - 0.15 13.0 3.5 44 5.2 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF1079 PF06435.11 CBZ32629.1 - 4.7 7.5 5.9 63 4.0 0.1 2.5 2 0 0 2 2 2 0 Repeat of unknown function (DUF1079) UQ_con PF00179.26 CBZ32631.1 - 1.1e-14 54.3 0.0 1.2e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBZ32631.1 - 0.0027 18.0 0.0 0.0029 17.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain LD_cluster2 PF18163.1 CBZ32631.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 SLOG cluster2 Tcp10_C PF07202.13 CBZ32632.1 - 3.5e-27 95.5 0.0 9.6e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 T-complex protein 10 C-terminus Seadorna_VP6 PF07407.11 CBZ32632.1 - 0.24 10.3 0.6 0.37 9.7 0.6 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein RhoGEF PF00621.20 CBZ32633.1 - 0.074 13.3 1.7 2 8.6 0.3 3.6 1 1 1 2 2 2 0 RhoGEF domain DUF4411 PF14367.6 CBZ32633.1 - 0.65 9.9 3.6 10 6.0 0.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4411) PriA_C PF18074.1 CBZ32633.1 - 1.5 9.7 8.7 0.49 11.2 0.2 4.8 4 0 0 4 4 4 0 Primosomal protein N C-terminal domain EMP24_GP25L PF01105.24 CBZ32633.1 - 2 8.3 11.3 0.42 10.5 0.3 4.5 4 1 0 4 4 4 0 emp24/gp25L/p24 family/GOLD Kinesin PF00225.23 CBZ32634.1 - 1.8e-92 309.8 0.0 2.5e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ32634.1 - 2.6e-16 59.9 0.0 5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding SAM_1 PF00536.30 CBZ32634.1 - 0.00056 20.3 0.2 0.00056 20.3 0.2 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBZ32634.1 - 0.046 13.8 0.2 0.1 12.7 0.2 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) BLOC1_2 PF10046.9 CBZ32634.1 - 0.055 13.8 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SE PF08491.10 CBZ32635.1 - 3.8e-57 193.5 0.0 5.4e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CBZ32635.1 - 1.6e-09 37.5 0.0 2.9e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CBZ32635.1 - 0.0013 17.9 0.1 0.89 8.5 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CBZ32635.1 - 0.0013 18.1 0.1 0.0051 16.1 0.1 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ32635.1 - 0.011 15.9 0.1 0.042 14.1 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CBZ32635.1 - 0.013 14.9 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GDI PF00996.18 CBZ32635.1 - 0.039 12.5 0.0 0.058 11.9 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_binding_2 PF00890.24 CBZ32635.1 - 0.048 12.7 0.1 0.076 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DNA_pol_A PF00476.20 CBZ32636.1 - 4.5e-37 128.0 0.1 1.4e-36 126.4 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 CBZ32636.1 - 0.00066 19.4 0.0 0.0027 17.4 0.0 2.1 3 0 0 3 3 3 1 3'-5' exonuclease Pkinase PF00069.25 CBZ32637.1 - 4.1e-51 173.9 0.0 4e-48 164.1 0.0 3.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32637.1 - 1.3e-19 70.5 0.0 6.3e-16 58.4 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CBZ32637.1 - 2.5e-05 23.4 0.0 3.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBZ32637.1 - 0.0022 17.9 0.0 0.016 15.1 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ32637.1 - 0.18 11.1 0.0 0.39 10.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like AAA_6 PF12774.7 CBZ32638.1 - 3.8e-142 473.1 0.0 1e-140 468.4 0.0 2.8 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CBZ32638.1 - 4.5e-133 444.9 0.4 6.2e-132 441.1 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CBZ32638.1 - 2.2e-110 369.5 1.9 2.2e-110 369.5 1.9 3.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ32638.1 - 1.1e-93 313.3 0.3 3.6e-93 311.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 CBZ32638.1 - 2e-85 286.9 11.3 2e-85 286.9 11.3 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 CBZ32638.1 - 7.8e-83 276.9 0.1 7.8e-83 276.9 0.1 3.4 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 CBZ32638.1 - 4.5e-77 259.3 0.1 1.4e-76 257.6 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 CBZ32638.1 - 5.7e-68 228.0 1.0 3.5e-63 212.4 0.3 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ32638.1 - 5.2e-46 156.4 0.0 1.3e-45 155.1 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ32638.1 - 1.8e-35 121.6 0.0 1.4e-21 76.8 0.0 4.7 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 CBZ32638.1 - 1.7e-26 92.4 0.2 7.9e-26 90.2 0.2 2.3 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CBZ32638.1 - 5.5e-24 84.7 0.3 2e-23 82.9 0.3 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBZ32638.1 - 1.9e-22 79.8 0.0 1.7e-07 31.3 0.0 5.7 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CBZ32638.1 - 9.4e-08 32.7 0.6 0.04 14.5 0.0 6.4 5 0 0 5 5 5 1 AAA domain AAA PF00004.29 CBZ32638.1 - 6.2e-07 29.9 0.0 0.075 13.5 0.0 3.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ32638.1 - 1.7e-05 25.3 4.6 0.56 10.6 0.1 5.9 5 1 1 6 6 5 1 AAA ATPase domain AAA_22 PF13401.6 CBZ32638.1 - 6.4e-05 23.2 0.4 5.5 7.3 0.0 5.0 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.6 CBZ32638.1 - 0.00023 21.5 0.7 0.59 10.4 0.0 3.8 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CBZ32638.1 - 0.0072 15.7 0.5 0.71 9.2 0.0 3.7 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CBZ32638.1 - 0.036 14.1 0.5 24 4.9 0.0 3.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CBZ32638.1 - 0.054 14.0 0.2 50 4.4 0.0 4.2 3 0 0 3 3 3 0 ABC transporter IstB_IS21 PF01695.17 CBZ32638.1 - 0.086 12.6 0.2 0.75 9.5 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CBZ32638.1 - 0.1 13.0 0.8 69 3.9 0.0 4.5 4 0 0 4 4 4 0 RNA helicase AAA_28 PF13521.6 CBZ32638.1 - 0.11 12.7 1.0 26 5.0 0.1 3.8 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CBZ32638.1 - 0.24 11.5 0.8 27 4.9 0.0 3.8 4 0 0 4 4 4 0 AAA domain GP3_package PF16677.5 CBZ32638.1 - 0.41 10.8 1.5 2 8.6 1.5 2.2 1 0 0 1 1 1 0 DNA-packaging protein gp3 Cpn60_TCP1 PF00118.24 CBZ32639.1 - 2.7e-161 537.5 6.6 3.1e-161 537.3 6.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FeoB_Cyto PF17910.1 CBZ32639.1 - 0.048 14.2 0.7 4.8 7.8 0.1 2.9 3 0 0 3 3 3 0 FeoB cytosolic helical domain Ribosomal_L44 PF00935.19 CBZ32640.1 - 1.2e-31 109.0 9.1 1.7e-31 108.5 9.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 P5CR_dimer PF14748.6 CBZ32641.1 - 2.6e-36 124.0 1.2 4.4e-36 123.3 1.2 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CBZ32641.1 - 7.2e-16 58.6 0.0 1.5e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CBZ32641.1 - 2.3e-06 27.9 0.0 4.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 CBZ32641.1 - 6.1e-05 22.7 0.2 0.00016 21.3 0.2 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CBZ32641.1 - 0.0086 16.1 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CBZ32641.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CbiC PF02570.15 CBZ32641.1 - 0.039 13.6 0.3 0.13 11.9 0.1 1.8 2 0 0 2 2 2 0 Precorrin-8X methylmutase NAD_Gly3P_dh_N PF01210.23 CBZ32641.1 - 0.098 12.6 1.1 0.51 10.3 1.1 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MFS_1 PF07690.16 CBZ32642.1 - 2.3e-16 59.7 31.5 5.7e-13 48.5 26.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ32642.1 - 4e-12 46.2 12.8 4e-12 46.2 12.8 2.2 2 1 0 2 2 2 1 Nodulin-like TssO PF17561.2 CBZ32642.1 - 0.00041 20.5 0.2 0.00041 20.5 0.2 2.4 2 0 0 2 2 2 1 Type VI secretion system, TssO LRR_4 PF12799.7 CBZ32643.1 - 4.2e-13 49.3 0.0 0.31 11.5 0.0 5.9 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ32643.1 - 0.016 15.3 0.2 16 5.9 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat Utp12 PF04003.12 CBZ32644.1 - 0.096 13.0 0.7 0.2 12.0 0.0 2.0 3 0 0 3 3 3 0 Dip2/Utp12 Family LRR_4 PF12799.7 CBZ32645.1 - 7.1e-09 35.8 15.6 7.4e-06 26.2 1.2 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ32645.1 - 4.6e-06 26.3 3.5 0.00082 19.1 2.3 2.6 2 0 0 2 2 2 2 Leucine rich repeat zn-ribbon_14 PF16503.5 CBZ32645.1 - 0.074 12.6 0.1 0.17 11.4 0.1 1.6 1 0 0 1 1 1 0 Zinc-ribbon SPOUT_MTase_2 PF14419.6 CBZ32645.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Selenoprotein_S PF06936.11 CBZ32645.1 - 0.12 12.2 0.5 0.26 11.1 0.5 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) LRR_1 PF00560.33 CBZ32645.1 - 0.73 10.6 2.6 7.5 7.5 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 CBZ32645.1 - 1.8 8.9 6.3 5.3 7.4 0.2 3.3 3 1 1 4 4 4 0 Leucine Rich repeat EF-hand_1 PF00036.32 CBZ32648.1 - 5.9e-23 78.7 0.0 4.6e-05 22.7 0.1 5.2 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 CBZ32648.1 - 1.8e-21 74.1 0.2 0.0002 21.0 0.0 5.1 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CBZ32648.1 - 4.8e-21 75.0 0.3 5.4e-10 39.6 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ32648.1 - 1.3e-14 52.9 0.5 9.6e-06 24.9 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBZ32648.1 - 2e-14 53.2 0.2 1.2e-06 28.2 0.0 4.0 3 2 2 5 5 5 3 EF-hand domain pair EF-hand_9 PF14658.6 CBZ32648.1 - 0.00076 19.8 0.1 1.7 9.0 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain DUF5580 PF17743.1 CBZ32648.1 - 0.0086 14.7 0.0 1.2 7.5 0.0 2.0 1 1 1 2 2 2 2 Family of unknown function (DUF5580) Phage_T4_Ndd PF06591.11 CBZ32648.1 - 0.031 14.1 0.2 0.041 13.7 0.2 1.2 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) Caleosin PF05042.13 CBZ32648.1 - 0.076 12.9 2.1 71 3.3 0.0 3.8 2 2 2 4 4 4 0 Caleosin related protein Spindle_Spc25 PF08234.12 CBZ32648.1 - 0.089 13.0 0.2 5.1 7.4 0.0 2.8 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 EF-hand_10 PF14788.6 CBZ32648.1 - 0.11 12.4 0.2 1 9.2 0.0 2.6 4 0 0 4 4 4 0 EF hand HECT PF00632.25 CBZ32649.1 - 1.1e-44 153.2 0.0 2.3e-44 152.1 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBZ32649.1 - 3.5e-24 85.2 0.2 5.7e-09 36.1 0.0 3.8 3 0 0 3 3 3 3 SPRY domain HECT PF00632.25 CBZ32650.1 - 1.1e-44 153.2 0.0 2.3e-44 152.1 0.0 1.5 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBZ32650.1 - 3.5e-24 85.2 0.2 5.7e-09 36.1 0.0 3.8 3 0 0 3 3 3 3 SPRY domain Ran_BP1 PF00638.18 CBZ32651.1 - 6.1e-26 91.1 1.2 8.1e-26 90.7 1.2 1.1 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CBZ32651.1 - 0.039 13.9 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 WH1 domain FlhE PF06366.13 CBZ32651.1 - 0.16 12.0 0.1 0.34 10.9 0.0 1.6 2 0 0 2 2 2 0 Flagellar protein FlhE DRMBL PF07522.14 CBZ32652.1 - 0.057 13.6 0.0 0.2 11.8 0.0 1.8 2 0 0 2 2 2 0 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CBZ32652.1 - 0.11 12.0 2.1 0.47 9.9 1.3 2.4 2 1 0 2 2 2 0 Beta-lactamase superfamily domain PIN_4 PF13638.6 CBZ32653.1 - 8.5e-18 64.9 0.0 1.6e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 PIN domain STPPase_N PF16891.5 CBZ32654.1 - 3.8e-05 24.0 0.0 6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain AAA PF00004.29 CBZ32655.1 - 7.5e-18 65.2 0.0 2e-17 63.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBZ32655.1 - 0.0012 18.6 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CBZ32655.1 - 0.013 15.1 0.1 0.078 12.5 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ32655.1 - 0.019 15.2 0.0 0.11 12.7 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ32655.1 - 0.032 14.6 0.0 0.032 14.6 0.0 3.2 3 2 0 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 CBZ32655.1 - 0.07 13.5 0.0 0.65 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 CBZ32655.1 - 0.096 13.0 0.0 0.34 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain IQ PF00612.27 CBZ32655.1 - 8 6.6 8.1 0.31 10.9 0.3 2.8 3 0 0 3 3 3 0 IQ calmodulin-binding motif PhoLip_ATPase_C PF16212.5 CBZ32656.1 - 3.3e-64 217.0 20.6 3.3e-64 217.0 20.6 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBZ32656.1 - 1e-22 79.6 2.1 1e-22 79.6 2.1 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CBZ32656.1 - 1.4e-10 41.8 0.1 2.6e-05 24.6 0.0 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ32656.1 - 4.1e-10 39.6 0.0 5.2e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBZ32656.1 - 8.8e-09 35.1 0.5 8.8e-09 35.1 0.5 3.6 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBZ32656.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NIF PF03031.18 CBZ32657.1 - 0.024 14.4 0.0 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase Gtr1_RagA PF04670.12 CBZ32659.1 - 3e-90 301.6 0.0 4e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 CBZ32659.1 - 2.3e-06 27.8 0.0 1.6e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ32659.1 - 5.3e-05 22.9 0.0 0.00014 21.5 0.0 1.7 2 0 0 2 2 2 1 Ras family Arf PF00025.21 CBZ32659.1 - 0.00019 20.9 0.0 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family RuvB_N PF05496.12 CBZ32659.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain KH_6 PF15985.5 CBZ32661.1 - 2.6e-12 46.9 0.1 1.9e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 KH domain PI3Ka PF00613.20 CBZ32662.1 - 3.3e-47 160.3 1.7 6.5e-47 159.3 1.7 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CBZ32662.1 - 8e-47 160.2 0.0 3e-46 158.3 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.18 CBZ32662.1 - 8.4e-12 45.2 0.0 2e-09 37.6 0.0 3.5 4 0 0 4 4 4 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 CBZ32662.1 - 8e-09 35.5 0.0 1.9e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF2811 PF10929.8 CBZ32662.1 - 0.11 12.8 0.6 7.4 6.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2811) Fumarate_red_D PF02313.17 CBZ32663.1 - 0.045 13.8 0.1 0.07 13.2 0.1 1.2 1 0 0 1 1 1 0 Fumarate reductase subunit D SNF2_N PF00176.23 CBZ32664.1 - 7e-21 74.3 0.0 1.6e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Tet_JBP PF12851.7 CBZ32664.1 - 1.7e-19 70.4 0.1 8.1e-16 58.3 0.0 2.2 1 1 1 2 2 2 2 Oxygenase domain of the 2OGFeDO superfamily Helicase_C PF00271.31 CBZ32664.1 - 2e-14 53.9 0.2 3.9e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ32664.1 - 5.7e-09 36.2 0.0 1.8e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ32664.1 - 0.0011 18.3 0.5 0.0018 17.6 0.5 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2095 PF09868.9 CBZ32664.1 - 0.024 14.6 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) DEAD PF00270.29 CBZ32664.1 - 0.036 13.8 0.0 0.1 12.4 0.0 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase cNMP_binding PF00027.29 CBZ32665.1 - 0.00043 20.3 0.1 8.2 6.6 0.0 4.0 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Arf PF00025.21 CBZ32666.1 - 3.3e-05 23.4 0.0 8.3e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_28 PF13521.6 CBZ32666.1 - 0.026 14.8 0.3 0.043 14.1 0.3 1.4 1 0 0 1 1 1 0 AAA domain DHHC PF01529.20 CBZ32667.1 - 7.3e-25 87.6 11.5 7.3e-25 87.6 11.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.17 CBZ32667.1 - 2.3 7.9 17.3 0.43 10.3 4.1 2.8 2 1 1 3 3 3 0 Yip1 domain COX8 PF02285.15 CBZ32667.1 - 6.2 6.8 6.9 0.26 11.2 0.6 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII DUF5108 PF17133.4 CBZ32668.1 - 0.041 13.9 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5108) PRP1_N PF06424.12 CBZ32668.1 - 0.054 13.9 0.3 0.054 13.9 0.3 1.8 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DnaJ PF00226.31 CBZ32669.1 - 2.9e-05 24.1 0.0 6.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain CH PF00307.31 CBZ32670.1 - 0.014 15.6 0.0 0.074 13.2 0.0 2.2 2 0 0 2 2 2 0 Calponin homology (CH) domain DUF1493 PF07377.12 CBZ32670.1 - 0.029 14.8 0.1 0.11 12.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Phage_GP20 PF06810.11 CBZ32670.1 - 0.086 12.6 3.6 0.24 11.2 3.6 1.7 1 0 0 1 1 1 0 Phage minor structural protein GP20 GrpE PF01025.19 CBZ32670.1 - 0.13 12.0 6.9 0.38 10.4 6.9 1.8 1 0 0 1 1 1 0 GrpE ZapB PF06005.12 CBZ32670.1 - 0.75 10.3 13.3 6.5 7.3 10.1 3.2 2 0 0 2 2 2 0 Cell division protein ZapB BORCS8 PF10167.9 CBZ32670.1 - 1.1 9.2 5.3 1.2 9.1 1.8 2.8 3 0 0 3 3 3 0 BLOC-1-related complex sub-unit 8 DnaJ PF00226.31 CBZ32671.1 - 3.2e-13 49.6 0.6 5.9e-13 48.7 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain Syntaxin-18_N PF10496.9 CBZ32671.1 - 2.4 8.5 4.4 1.1 9.5 0.1 2.5 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus IU_nuc_hydro PF01156.19 CBZ32673.1 - 5.4e-70 236.4 0.1 6.3e-70 236.1 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MOZ_SAS PF01853.18 CBZ32674.1 - 1.8e-63 213.5 0.0 2.9e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBZ32674.1 - 9.6e-09 34.7 0.3 5e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 MYST family zinc finger domain Tudor-knot PF11717.8 CBZ32674.1 - 1.6e-08 34.3 0.6 2.9e-08 33.5 0.1 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CBZ32674.1 - 0.00054 20.3 0.1 0.003 17.9 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ32674.1 - 0.0063 16.7 0.0 0.076 13.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family zf-C2H2_4 PF13894.6 CBZ32674.1 - 0.08 13.8 0.1 0.33 11.9 0.1 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger Acetyltransf_CG PF14542.6 CBZ32674.1 - 0.089 12.9 0.0 5.7 7.1 0.1 2.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 CBZ32674.1 - 0.13 12.2 0.0 0.49 10.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-Di19 PF05605.12 CBZ32674.1 - 0.75 10.1 5.3 5 7.5 0.8 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ribosomal_L12 PF00542.19 CBZ32675.1 - 8.4e-17 61.3 3.7 8.4e-17 61.3 3.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain PSII_Pbs27 PF13326.6 CBZ32675.1 - 0.13 12.6 3.2 0.45 10.8 2.0 2.0 2 0 0 2 2 2 0 Photosystem II Pbs27 PepSY_2 PF13670.6 CBZ32675.1 - 0.26 11.3 6.0 1.4 9.0 2.2 2.4 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Ribosomal_L12_N PF16320.5 CBZ32675.1 - 0.93 9.3 0.0 0.93 9.3 0.0 2.9 3 1 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain Chromo PF00385.24 CBZ32676.1 - 0.00021 21.1 0.3 0.0004 20.2 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_M32 PF02074.15 CBZ32678.1 - 1.1e-139 466.4 0.0 1.2e-139 466.2 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase CZB PF13682.6 CBZ32678.1 - 4.6 7.8 5.7 4.6 7.8 1.1 3.0 3 0 0 3 3 3 0 Chemoreceptor zinc-binding domain Thioredoxin_8 PF13905.6 CBZ32679.1 - 9.6e-08 32.3 0.1 1.6e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 CBZ32679.1 - 0.00025 20.8 0.1 0.0003 20.5 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CBZ32679.1 - 0.00057 19.8 0.1 0.00078 19.4 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family BBIP10 PF14777.6 CBZ32680.1 - 3.1e-25 87.5 2.4 4.7e-25 86.9 2.4 1.2 1 0 0 1 1 1 1 Cilia BBSome complex subunit 10 US30 PF17624.2 CBZ32680.1 - 0.16 11.0 0.7 0.22 10.6 0.7 1.1 1 0 0 1 1 1 0 Family of unknown function DUF4201 PF13870.6 CBZ32681.1 - 3.8e-30 104.9 8.7 3.8e-30 104.9 8.7 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4201) Med29 PF11568.8 CBZ32681.1 - 0.069 13.4 1.5 0.19 11.9 0.3 2.3 2 1 0 2 2 2 0 Mediator complex subunit 29 DUF720 PF05302.11 CBZ32681.1 - 0.11 12.3 2.7 0.26 11.1 2.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Phyto-Amp PF15438.6 CBZ32681.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma MCM_N PF14551.6 CBZ32681.1 - 0.34 11.5 5.9 3.3 8.3 0.2 3.0 3 0 0 3 3 3 0 MCM N-terminal domain Csm1_N PF18504.1 CBZ32681.1 - 5.6 7.4 22.1 0.81 10.1 3.3 4.3 3 1 1 4 4 4 0 Csm1 N-terminal domain PX PF00787.24 CBZ32682.1 - 1.5e-10 41.1 0.0 9.1e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 PX domain Sec5 PF15469.6 CBZ32683.1 - 0.00014 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 FAM110_C PF14160.6 CBZ32683.1 - 0.34 12.0 1.7 2 9.5 1.7 2.5 1 0 0 1 1 1 0 Centrosome-associated C terminus HIT PF01230.23 CBZ32684.1 - 3.3e-23 82.3 0.1 4.4e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CBZ32684.1 - 3.4e-14 53.3 0.0 4.6e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CBZ32684.1 - 0.015 15.1 4.1 0.017 15.0 2.2 2.0 2 1 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 TRAP-gamma PF07074.12 CBZ32685.1 - 2e-08 34.0 2.0 0.00055 19.5 0.2 2.1 2 0 0 2 2 2 2 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4386 PF14329.6 CBZ32685.1 - 0.023 14.6 1.6 0.039 13.8 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4386) DUF3270 PF11674.8 CBZ32685.1 - 1.5 9.1 5.2 0.3 11.3 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) VWA_3 PF13768.6 CBZ32686.1 - 3.3e-09 36.8 0.2 8.1e-09 35.6 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 CBZ32686.1 - 0.0033 17.3 0.0 0.01 15.7 0.0 1.9 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Na_Ca_ex PF01699.24 CBZ32687.1 - 2.1e-07 31.0 34.9 0.00074 19.5 7.9 3.4 3 2 1 4 4 4 2 Sodium/calcium exchanger protein DUF5628 PF18621.1 CBZ32689.1 - 0.04 14.4 0.2 0.074 13.5 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5628) Proteasome PF00227.26 CBZ32691.1 - 1.4e-50 171.4 0.0 1.9e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ32691.1 - 4.2e-13 48.7 0.3 7.3e-13 47.9 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AA_permease_2 PF13520.6 CBZ32692.1 - 8e-33 113.9 41.7 8.6e-33 113.8 41.0 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CBZ32692.1 - 3.3e-12 45.8 35.2 8.9e-12 44.3 35.2 1.6 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 CBZ32693.1 - 3.1e-22 78.9 21.7 4.3e-22 78.4 21.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Vps55 PF04133.14 CBZ32693.1 - 0.04 13.9 5.1 0.54 10.2 2.0 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting 55 IPK PF03770.16 CBZ32694.1 - 1.5e-42 145.7 0.1 2.4e-42 145.1 0.1 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Thr_synth_N PF14821.6 CBZ32695.1 - 2.8e-14 53.1 0.0 1.2e-13 51.1 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 CBZ32695.1 - 2.9e-10 40.0 0.0 6.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-CW PF07496.15 CBZ32696.1 - 0.00038 20.4 3.0 0.00038 20.4 3.0 1.7 2 0 0 2 2 2 1 CW-type Zinc Finger Bromodomain PF00439.25 CBZ32696.1 - 0.12 12.4 0.0 1.5 9.0 0.0 2.2 1 1 0 1 1 1 0 Bromodomain Choline_transpo PF04515.12 CBZ32698.1 - 3.6e-53 180.9 41.9 3.6e-53 180.9 41.9 1.9 3 0 0 3 3 3 1 Plasma-membrane choline transporter APC_u15 PF16636.5 CBZ32698.1 - 0.04 14.3 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 G-patch_2 PF12656.7 CBZ32699.1 - 0.022 14.8 0.1 0.022 14.8 0.1 1.0 1 0 0 1 1 1 0 G-patch domain DUF3850 PF12961.7 CBZ32700.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3850) ATP-synt_D PF01813.17 CBZ32701.1 - 0.022 14.6 0.1 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 ATP synthase subunit D UTP25 PF06862.12 CBZ32702.1 - 1.7e-109 366.7 1.1 5.2e-101 338.8 0.1 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Dzip-like_N PF13815.6 CBZ32703.1 - 8.9e-39 132.1 4.3 8.9e-39 132.1 4.3 2.0 2 0 0 2 2 2 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-Di19 PF05605.12 CBZ32703.1 - 0.00084 19.6 0.3 0.0016 18.7 0.3 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CBZ32703.1 - 0.017 15.9 1.2 0.036 14.9 1.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CBZ32703.1 - 0.12 12.7 0.6 0.48 10.8 0.1 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CBZ32703.1 - 0.14 12.6 1.4 0.32 11.5 1.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type mRNA_triPase PF02940.15 CBZ32704.1 - 2.6e-07 30.6 0.0 5.8e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 mRNA capping enzyme, beta chain Pyr_redox_2 PF07992.14 CBZ32705.1 - 1.2e-16 60.8 0.0 5.7e-16 58.6 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ32705.1 - 1.5e-09 38.2 0.0 4.9e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBZ32705.1 - 9.6e-06 25.4 0.0 0.041 13.5 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CBZ32705.1 - 1.3e-05 24.5 0.0 0.0083 15.2 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 CBZ32705.1 - 5.8e-05 23.1 0.0 0.058 13.4 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CBZ32705.1 - 6.9e-05 23.0 0.8 0.4 10.9 0.0 2.9 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CBZ32705.1 - 0.0018 17.5 0.0 0.0069 15.6 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CBZ32705.1 - 0.0028 16.9 0.0 0.061 12.6 0.0 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 CBZ32705.1 - 0.0054 17.1 0.0 1.5 9.3 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CBZ32705.1 - 0.095 11.9 0.1 0.81 8.9 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 CBZ32705.1 - 0.11 11.6 0.0 13 4.7 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 CBZ32705.1 - 0.13 12.1 0.0 0.62 9.9 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 CBZ32705.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SbsC_C PF18058.1 CBZ32705.1 - 0.16 12.2 0.1 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 SbsC C-terminal domain TrkA_N PF02254.18 CBZ32705.1 - 0.17 12.1 0.0 13 6.1 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain CS PF04969.16 CBZ32706.1 - 5.6e-16 59.3 0.1 9.4e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 CS domain Nudc_N PF14050.6 CBZ32706.1 - 6.5e-15 54.9 0.2 1.5e-14 53.7 0.2 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. DUF2052 PF09747.9 CBZ32706.1 - 1.1 9.3 17.3 0.23 11.6 10.7 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Hid1 PF12722.7 CBZ32706.1 - 1.3 7.1 8.1 0.032 12.4 2.3 1.3 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF853 PF05872.12 CBZ32706.1 - 1.5 7.3 8.1 2.9 6.4 8.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Neur_chan_memb PF02932.16 CBZ32706.1 - 7 6.6 7.6 0.63 10.1 2.6 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Cys_Met_Meta_PP PF01053.20 CBZ32707.1 - 1.5e-116 389.1 0.0 1.8e-116 388.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CBZ32707.1 - 0.025 13.6 1.0 0.028 13.4 0.1 1.5 2 0 0 2 2 2 0 Aminotransferase class-V Vac7 PF12751.7 CBZ32709.1 - 0.094 12.1 0.3 0.11 11.9 0.3 1.0 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Amastin PF07344.11 CBZ32710.1 - 7.5e-05 22.6 22.0 0.00081 19.3 19.5 2.5 1 1 1 2 2 2 2 Amastin surface glycoprotein DUF4094 PF13334.6 CBZ32711.1 - 0.11 13.0 4.6 7.2 7.1 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) YabA PF06156.13 CBZ32711.1 - 0.39 11.4 4.0 15 6.3 0.0 3.7 4 0 0 4 4 4 0 Initiation control protein YabA UPF0242 PF06785.11 CBZ32711.1 - 0.42 10.7 9.2 1.4 8.9 0.3 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF5082 PF16888.5 CBZ32711.1 - 1.1 9.5 5.9 8.8 6.6 0.9 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 CBZ32711.1 - 3.3 6.5 16.3 3 6.6 0.3 3.2 3 0 0 3 3 3 0 Spc7 kinetochore protein FA_desaturase PF00487.24 CBZ32712.1 - 2.5e-17 63.6 17.1 2.5e-17 63.6 17.1 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBZ32712.1 - 1.6e-08 34.6 0.1 6.9e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FemAB PF02388.16 CBZ32713.1 - 0.044 12.7 1.7 0.051 12.5 1.7 1.0 1 0 0 1 1 1 0 FemAB family Ion_trans_2 PF07885.16 CBZ32714.1 - 2.8e-10 40.0 5.4 1.1e-09 38.1 5.4 2.0 1 0 0 1 1 1 1 Ion channel Ion_trans_2 PF07885.16 CBZ32715.1 - 3.2e-11 43.0 8.8 3.2e-11 43.0 8.8 2.6 2 0 0 2 2 2 1 Ion channel Lig_chan PF00060.26 CBZ32715.1 - 0.00014 21.7 1.5 0.00014 21.7 1.5 2.1 2 1 0 2 2 2 1 Ligand-gated ion channel Ion_trans PF00520.31 CBZ32715.1 - 0.00026 20.3 21.3 0.00026 20.3 21.3 2.1 2 1 1 3 3 3 1 Ion transport protein DUF5493 PF17597.2 CBZ32715.1 - 0.84 9.9 5.8 0.48 10.7 1.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5493) TMCCDC2 PF15844.5 CBZ32716.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane and coiled-coil domain-containing protein 2 Shisa PF13908.6 CBZ32717.1 - 0.023 14.9 0.3 0.023 14.9 0.3 2.3 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator T2SSM PF04612.12 CBZ32717.1 - 0.031 14.4 0.3 0.031 14.4 0.3 2.0 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein M WD40 PF00400.32 CBZ32718.1 - 1.8e-21 76.0 18.6 0.0027 18.5 0.0 9.9 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ32718.1 - 1.1e-08 35.3 0.0 27 5.2 0.0 8.3 6 2 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CBZ32718.1 - 2.7e-06 27.6 0.2 5e-06 26.8 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family PS-DH PF14765.6 CBZ32718.1 - 0.015 14.5 1.1 0.093 11.9 0.1 2.2 2 0 0 2 2 2 0 Polyketide synthase dehydratase Ge1_WD40 PF16529.5 CBZ32718.1 - 0.23 10.4 1.2 23 3.8 0.0 3.9 4 1 0 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Complex1_LYR PF05347.15 CBZ32719.1 - 0.00067 19.7 0.2 0.0012 18.9 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Chibby PF14645.6 CBZ32719.1 - 0.0095 16.3 0.0 4.4 7.7 0.0 2.1 2 0 0 2 2 2 2 Chibby family SpoU_methylase PF00588.19 CBZ32721.1 - 2.3e-10 40.8 0.0 0.00033 20.8 0.0 2.3 2 0 0 2 2 2 2 SpoU rRNA Methylase family Mitochondr_Som1 PF11093.8 CBZ32721.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial export protein Som1 Nrap_D2 PF17403.2 CBZ32721.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Spt5_N PF11942.8 CBZ32722.1 - 0.0017 19.3 2.3 0.0017 19.3 2.3 2.0 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 CBZ32722.1 - 0.0087 14.4 1.7 0.015 13.6 1.7 1.3 1 0 0 1 1 1 1 CDC45-like protein Sigma70_ner PF04546.13 CBZ32722.1 - 1.3 8.9 4.7 3 7.7 4.7 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-LSD1 PF06943.12 CBZ32724.1 - 7.4e-07 28.9 9.3 7.4e-07 28.9 9.3 3.2 3 0 0 3 3 3 1 LSD1 zinc finger PHD PF00628.29 CBZ32724.1 - 0.063 13.2 1.1 0.063 13.2 1.1 2.2 3 0 0 3 3 3 0 PHD-finger DUF1610 PF07754.11 CBZ32724.1 - 0.35 10.9 5.0 0.96 9.5 5.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) DZR PF12773.7 CBZ32724.1 - 2.5 8.2 10.9 19 5.4 10.9 2.1 1 1 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.22 CBZ32724.1 - 6.1 6.8 9.5 13 5.7 1.2 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ELO PF01151.18 CBZ32725.1 - 1.9e-37 129.2 9.2 2.3e-37 128.9 9.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ32726.1 - 8.1e-66 222.1 15.0 9.3e-66 221.9 15.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1240 PF06836.12 CBZ32726.1 - 0.021 15.3 3.6 0.039 14.5 2.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1240) DUF5033 PF16436.5 CBZ32726.1 - 0.088 12.7 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) ELO PF01151.18 CBZ32727.1 - 3.7e-62 210.1 13.4 4.3e-62 209.9 13.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ32728.1 - 3.6e-63 213.4 13.4 4.1e-63 213.2 13.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ32730.1 - 1e-68 231.6 5.4 1.2e-68 231.4 5.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3177 PF11375.8 CBZ32730.1 - 0.12 12.2 5.0 1.5 8.6 5.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3177) ELO PF01151.18 CBZ32731.1 - 9.7e-77 257.9 23.4 1.1e-76 257.7 23.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ32732.1 - 7.4e-31 107.6 1.7 8.4e-31 107.4 1.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family CrgA PF06781.12 CBZ32732.1 - 0.16 12.0 1.0 0.27 11.3 1.0 1.3 1 0 0 1 1 1 0 Cell division protein CrgA ELO PF01151.18 CBZ32733.1 - 2.4e-77 259.9 19.0 2.8e-77 259.6 19.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ32734.1 - 3.6e-75 252.7 9.0 4.7e-75 252.4 9.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Peptidase_U4 PF03419.13 CBZ32734.1 - 0.39 9.9 6.1 0.63 9.3 6.1 1.4 1 0 0 1 1 1 0 Sporulation factor SpoIIGA ELO PF01151.18 CBZ32735.1 - 2.2e-84 282.9 16.8 2.8e-84 282.5 16.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ32736.1 - 8.2e-71 238.4 19.5 9.7e-71 238.2 19.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ32737.1 - 8.2e-74 248.3 20.0 9.8e-74 248.0 20.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family ELO PF01151.18 CBZ32738.1 - 1.2e-74 251.0 22.9 1.4e-74 250.8 22.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family EMC3_TMCO1 PF01956.16 CBZ32738.1 - 1.1 9.0 5.5 3.5 7.3 4.7 2.2 2 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Ras PF00071.22 CBZ32740.1 - 9.6e-36 122.8 0.0 1.3e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ32740.1 - 3.2e-26 91.9 0.0 5e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ32740.1 - 2.2e-09 37.0 0.0 3.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ32740.1 - 2e-05 24.0 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ32740.1 - 0.017 15.2 0.0 0.038 14.1 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CBZ32740.1 - 0.033 14.6 0.1 0.5 10.7 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CBZ32740.1 - 0.034 13.7 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CBZ32740.1 - 0.22 10.9 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Ribosomal_L21p PF00829.21 CBZ32742.1 - 1.4e-18 67.0 0.0 1.7e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein PsbP PF01789.16 CBZ32742.1 - 0.026 14.7 0.1 0.046 13.9 0.1 1.4 1 0 0 1 1 1 0 PsbP Glyco_hydro_67N PF03648.14 CBZ32743.1 - 0.51 10.6 14.0 0.4 11.0 1.0 4.9 4 1 1 5 5 5 0 Glycosyl hydrolase family 67 N-terminus Kinesin PF00225.23 CBZ32745.1 - 6.2e-90 301.5 0.0 1.1e-89 300.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ32745.1 - 7.8e-19 68.1 0.0 4.1e-18 65.7 0.0 2.0 1 1 0 1 1 1 1 Microtubule binding DUF4201 PF13870.6 CBZ32746.1 - 1.5e-33 116.0 18.4 1.5e-33 116.0 18.4 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) JIP_LZII PF16471.5 CBZ32746.1 - 0.0072 16.5 2.0 0.0072 16.5 2.0 4.7 4 2 2 6 6 6 2 JNK-interacting protein leucine zipper II Med30 PF11315.8 CBZ32746.1 - 0.015 15.5 0.6 0.015 15.5 0.6 2.9 3 0 0 3 3 3 0 Mediator complex subunit 30 KELK PF15796.5 CBZ32746.1 - 0.026 15.0 7.5 0.026 15.0 7.5 4.2 4 1 1 5 5 5 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SlyX PF04102.12 CBZ32746.1 - 0.24 12.0 0.0 0.24 12.0 0.0 5.5 4 2 1 5 5 5 0 SlyX Noelin-1 PF12308.8 CBZ32746.1 - 3.6 7.6 0.0 3.6 7.6 0.0 4.1 2 1 4 6 6 6 0 Neurogenesis glycoprotein DUF16 PF01519.16 CBZ32746.1 - 4.7 7.7 0.0 4.7 7.7 0.0 4.8 3 1 2 5 5 5 0 Protein of unknown function DUF16 OstA PF03968.14 CBZ32746.1 - 8.7 6.6 9.1 0.86 9.8 1.2 3.0 1 1 2 3 3 3 0 OstA-like protein Pkinase PF00069.25 CBZ32747.1 - 2.7e-42 144.9 0.0 4.7e-23 81.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32747.1 - 2.9e-13 49.7 0.0 1e-08 34.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ32747.1 - 0.0004 20.4 0.0 0.0007 19.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBZ32747.1 - 0.043 13.4 0.0 0.064 12.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 CBZ32747.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family SNF2_N PF00176.23 CBZ32748.1 - 1.6e-59 201.4 0.0 3.7e-59 200.2 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ32748.1 - 7.3e-19 68.2 0.2 7.1e-18 65.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ32748.1 - 6.4e-08 32.8 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBZ32748.1 - 1.5e-05 24.9 0.0 5.6e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase YebO PF13974.6 CBZ32748.1 - 5.5 7.2 6.9 0.52 10.4 0.4 2.7 2 0 0 2 2 2 0 YebO-like protein DUF1935 PF09149.10 CBZ32749.1 - 5.6e-40 135.9 0.2 6.3e-40 135.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ32750.1 - 5.6e-40 135.9 0.2 6.3e-40 135.7 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF4070 PF13282.6 CBZ32752.1 - 0.17 12.0 0.1 0.43 10.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) PP2C PF00481.21 CBZ32754.1 - 1e-48 166.2 0.0 5.3e-48 163.9 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ32754.1 - 2.5e-06 27.3 0.4 2.5e-06 27.3 0.4 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C GSH_synth_ATP PF03917.17 CBZ32755.1 - 2.7e-65 220.6 0.0 4.2e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CBZ32755.1 - 3.2e-30 104.6 0.1 6.4e-30 103.6 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Ribonuc_P_40 PF08584.11 CBZ32755.1 - 0.056 12.7 0.4 0.094 12.0 0.4 1.3 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit DNA_pol_A PF00476.20 CBZ32756.1 - 7.8e-38 130.5 0.0 8.7e-37 127.1 0.0 2.4 2 1 0 2 2 2 1 DNA polymerase family A Mito_fiss_reg PF05308.11 CBZ32757.1 - 0.07 13.2 0.3 0.07 13.2 0.3 3.4 4 1 0 4 4 4 0 Mitochondrial fission regulator DUF4315 PF14193.6 CBZ32757.1 - 0.14 12.2 2.7 0.27 11.3 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) SlyX PF04102.12 CBZ32757.1 - 3.7 8.2 10.4 13 6.5 0.2 4.3 3 1 1 4 4 4 0 SlyX DUF1451 PF07295.11 CBZ32757.1 - 7.2 6.6 8.9 2.5 8.1 0.6 3.1 3 0 0 3 3 3 0 Zinc-ribbon containing domain Ribosomal_L16 PF00252.18 CBZ32759.1 - 5.9e-16 58.7 0.0 7e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PAP_assoc PF03828.19 CBZ32760.1 - 1.9e-16 60.0 0.0 2.5e-11 43.6 0.0 3.0 3 0 0 3 3 3 2 Cid1 family poly A polymerase zf-MYST PF17772.1 CBZ32760.1 - 0.095 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 MYST family zinc finger domain NTP_transf_2 PF01909.23 CBZ32760.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain PRK PF00485.18 CBZ32761.1 - 3.3e-07 30.2 0.0 0.00033 20.5 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CBZ32761.1 - 0.00023 21.7 0.0 0.15 12.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ32761.1 - 0.0018 18.7 0.0 0.0028 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CBZ32761.1 - 0.0037 16.9 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CBZ32761.1 - 0.0069 15.7 0.0 0.022 14.0 0.0 1.9 2 1 1 3 3 3 1 Zeta toxin AAA_30 PF13604.6 CBZ32761.1 - 0.011 15.4 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBZ32761.1 - 0.017 15.7 0.0 0.028 14.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Ploopntkinase3 PF18751.1 CBZ32761.1 - 0.019 14.9 0.0 0.081 12.8 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 dNK PF01712.19 CBZ32761.1 - 0.019 14.8 0.0 3.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 CBZ32761.1 - 0.027 14.5 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CBZ32761.1 - 0.048 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CBZ32761.1 - 0.08 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 CBZ32761.1 - 0.082 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 CBZ32761.1 - 0.082 13.3 0.0 6 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBZ32761.1 - 0.11 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.10 CBZ32761.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 CBZ32761.1 - 0.13 12.4 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CBZ32761.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 CBZ32761.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 CBZ32761.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TERF2_RBM PF16772.5 CBZ32761.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif Na_H_Exchanger PF00999.21 CBZ32762.1 - 1.7e-17 63.3 27.4 3.2e-17 62.4 27.4 1.5 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Mito_carr PF00153.27 CBZ32763.1 - 8.6e-25 86.5 1.3 9.8e-12 44.6 0.0 3.3 2 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CBZ32764.1 - 3e-06 27.1 0.0 0.016 15.1 0.0 3.4 3 1 1 4 4 4 2 Mitochondrial carrier protein Maff2 PF12750.7 CBZ32764.1 - 0.18 11.7 1.6 0.77 9.6 0.3 2.4 2 0 0 2 2 2 0 Maff2 family Sulfotransfer_3 PF13469.6 CBZ32767.1 - 1e-06 29.3 0.0 1.7e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family DUF202 PF02656.15 CBZ32768.1 - 1.5e-16 60.5 1.2 7.4e-16 58.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Autoind_synth PF00765.17 CBZ32769.1 - 0.18 11.3 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Autoinducer synthase COQ9 PF08511.11 CBZ32770.1 - 1.3e-06 28.1 0.0 2.7e-05 23.8 0.0 2.6 2 0 0 2 2 2 1 COQ9 FTA4 PF13093.6 CBZ32770.1 - 0.097 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_6 PF12774.7 CBZ32771.1 - 3.4e-141 469.9 2.2 1.4e-139 464.7 0.0 3.9 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ32771.1 - 2.3e-108 362.8 0.3 2.3e-108 362.8 0.3 3.2 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ32771.1 - 7.2e-93 310.7 0.0 3.4e-92 308.4 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ32771.1 - 1.4e-81 274.1 0.1 8.5e-81 271.5 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ32771.1 - 9.1e-72 240.7 0.4 9.1e-72 240.7 0.4 2.9 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ32771.1 - 1.3e-55 187.7 2.3 6.7e-51 172.4 0.0 4.4 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 CBZ32771.1 - 1e-44 153.0 7.0 2.4e-44 151.8 7.0 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CBZ32771.1 - 3.1e-40 137.0 0.0 7.5e-38 129.3 0.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CBZ32771.1 - 3.3e-26 92.1 0.0 2.7e-25 89.1 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBZ32771.1 - 1.3e-20 73.8 2.3 2.9e-05 24.1 0.0 5.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CBZ32771.1 - 2.3e-17 63.0 0.0 7e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CBZ32771.1 - 3.3e-15 56.3 0.0 9.3e-14 51.6 0.0 3.2 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 CBZ32771.1 - 3.3e-05 24.2 18.1 0.026 14.8 0.0 7.7 7 1 1 8 8 7 1 AAA domain T2SSE PF00437.20 CBZ32771.1 - 7.5e-05 21.9 1.5 0.0021 17.2 0.1 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF815 PF05673.13 CBZ32771.1 - 0.00019 20.7 0.0 0.68 9.0 0.0 3.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA PF00004.29 CBZ32771.1 - 0.00039 20.8 0.8 2 8.8 0.0 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ32771.1 - 0.00045 20.6 20.8 0.061 13.7 0.1 7.3 7 1 0 7 7 6 2 AAA ATPase domain AAA_29 PF13555.6 CBZ32771.1 - 0.004 16.9 1.6 4.1 7.2 0.1 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CBZ32771.1 - 0.0073 15.7 1.1 3.6 6.9 0.1 4.3 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CBZ32771.1 - 0.011 16.2 1.8 4.8 7.7 0.0 4.7 4 0 0 4 4 3 0 AAA domain FtsK_SpoIIIE PF01580.18 CBZ32771.1 - 0.053 12.9 1.6 2.5 7.4 0.1 3.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family Macoilin PF09726.9 CBZ32771.1 - 0.13 10.7 6.5 0.29 9.6 6.5 1.5 1 0 0 1 1 1 0 Macoilin family RNA_helicase PF00910.22 CBZ32771.1 - 0.21 12.0 0.2 19 5.7 0.0 4.0 4 0 0 4 4 4 0 RNA helicase Fzo_mitofusin PF04799.13 CBZ32771.1 - 7.7 6.0 11.0 3.3 7.2 0.6 3.0 2 0 0 2 2 2 0 fzo-like conserved region Pkinase PF00069.25 CBZ32772.1 - 8.2e-44 149.9 0.0 4.6e-43 147.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32772.1 - 3.3e-17 62.6 0.0 5.9e-16 58.5 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase PQ-loop PF04193.14 CBZ32774.1 - 3.3e-28 97.2 4.3 2e-13 49.9 0.2 2.4 2 0 0 2 2 2 2 PQ loop repeat Kinesin PF00225.23 CBZ32776.1 - 5.5e-22 78.1 1.0 8.7e-22 77.5 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 CBZ32776.1 - 0.0038 17.4 3.4 0.0076 16.4 3.4 1.5 1 1 0 1 1 1 1 Kinesin-associated ADIP PF11559.8 CBZ32776.1 - 0.051 13.7 15.0 0.45 10.6 10.5 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Noelin-1 PF12308.8 CBZ32776.1 - 0.22 11.5 3.4 0.45 10.5 1.2 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein Spc7 PF08317.11 CBZ32776.1 - 0.24 10.2 13.8 0.33 9.8 13.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 CBZ32776.1 - 0.78 8.3 4.4 1 7.9 4.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Uso1_p115_C PF04871.13 CBZ32776.1 - 0.98 9.8 18.4 0.45 10.9 15.5 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cnn_1N PF07989.11 CBZ32776.1 - 1.8 8.8 12.9 4.8 7.4 2.4 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 LPP PF04728.13 CBZ32776.1 - 2.9 8.4 8.7 1.1 9.7 0.8 2.9 3 0 0 3 3 3 0 Lipoprotein leucine-zipper Kinesin PF00225.23 CBZ32777.1 - 4.1e-31 108.1 0.0 4.7e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ32777.1 - 1.2e-17 64.3 0.0 1.5e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Microtubule binding PhoH PF02562.16 CBZ32777.1 - 0.2 11.1 0.1 0.29 10.6 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein WD40 PF00400.32 CBZ32778.1 - 0.085 13.8 5.8 3.6 8.6 0.3 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat CSD PF00313.22 CBZ32779.1 - 5.3e-11 42.2 1.6 2.4e-06 27.3 0.8 3.7 4 0 0 4 4 4 2 'Cold-shock' DNA-binding domain S1-like PF14444.6 CBZ32779.1 - 0.066 13.2 3.8 0.29 11.1 0.2 2.9 3 0 0 3 3 3 0 S1-like Tub PF01167.18 CBZ32780.1 - 6.9e-32 111.1 0.0 1.2e-29 103.8 0.0 2.6 2 1 0 2 2 2 2 Tub family FAD_binding_4 PF01565.23 CBZ32780.1 - 0.089 12.5 1.2 0.18 11.6 1.2 1.4 1 0 0 1 1 1 0 FAD binding domain Enolase_C PF00113.22 CBZ32782.1 - 8.4e-128 425.7 0.0 1.2e-127 425.3 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CBZ32782.1 - 4.1e-58 195.2 0.1 7.1e-58 194.5 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CBZ32782.1 - 2.9e-07 30.3 0.0 4.5e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CBZ32782.1 - 0.0006 19.0 0.1 0.0006 19.0 0.1 1.5 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Ras PF00071.22 CBZ32783.1 - 6e-09 35.7 0.0 8.5e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ32783.1 - 1.3e-06 28.7 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 CBZ32783.1 - 0.056 13.0 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PAP_central PF04928.17 CBZ32784.1 - 4.2e-55 186.4 0.0 6.7e-55 185.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CBZ32784.1 - 1.3e-34 119.3 0.0 2.4e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CBZ32784.1 - 1.5e-05 25.2 0.0 3.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.6 CBZ32784.1 - 0.0058 16.8 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm Carb_kinase PF01256.17 CBZ32785.1 - 4.1e-47 160.7 6.5 4.1e-47 160.7 6.5 1.6 2 0 0 2 2 2 1 Carbohydrate kinase YjeF_N PF03853.15 CBZ32785.1 - 2.7e-45 154.3 0.0 2.7e-45 154.3 0.0 2.3 2 1 1 3 3 3 1 YjeF-related protein N-terminus PSS PF03034.15 CBZ32786.1 - 4.7e-98 328.3 12.6 6.8e-98 327.8 12.6 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF4381 PF14316.6 CBZ32786.1 - 0.064 13.5 11.5 5.3 7.3 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) NIF PF03031.18 CBZ32787.1 - 3.6e-13 49.6 0.0 3.9e-06 26.7 0.1 2.1 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase DUF4795 PF16043.5 CBZ32788.1 - 0.0033 17.1 31.7 5.1 6.6 2.4 5.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4795) SKA2 PF16740.5 CBZ32788.1 - 0.0071 16.1 14.6 1.2 8.9 0.3 6.4 5 1 1 7 7 7 1 Spindle and kinetochore-associated protein 2 Bacillus_HBL PF05791.11 CBZ32788.1 - 0.085 12.7 1.5 0.47 10.3 0.2 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) LPP PF04728.13 CBZ32788.1 - 0.16 12.4 0.2 0.16 12.4 0.2 5.5 6 0 0 6 6 6 0 Lipoprotein leucine-zipper GPS2_interact PF15784.5 CBZ32788.1 - 1.8 9.0 9.6 0.23 11.9 0.1 3.4 4 0 0 4 4 4 0 G-protein pathway suppressor 2-interacting domain TSC22 PF01166.18 CBZ32788.1 - 2.4 8.5 4.9 16 5.9 0.4 3.9 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF724 PF05266.14 CBZ32788.1 - 2.5 7.9 11.3 3.3 7.5 0.5 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF724) DUF1515 PF07439.11 CBZ32788.1 - 3.9 7.5 8.8 1.5 8.9 0.6 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1515) COG2 PF06148.11 CBZ32788.1 - 5.6 7.1 15.4 7.9 6.6 0.6 5.0 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 CBZ32788.1 - 6.1 5.6 27.1 2.8 6.8 2.5 4.8 3 2 1 5 5 5 0 Spc7 kinetochore protein HTH_1 PF00126.27 CBZ32789.1 - 0.14 12.1 5.5 0.37 10.8 0.3 3.1 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family HTH_37 PF13744.6 CBZ32790.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Stevor PF17410.2 CBZ32791.1 - 0.24 10.9 0.3 0.36 10.4 0.3 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ubiquitin PF00240.23 CBZ32793.1 - 7.8e-05 22.3 0.0 8.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBZ32793.1 - 0.073 12.9 0.0 0.08 12.8 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like F420_oxidored PF03807.17 CBZ32794.1 - 1.3e-06 28.9 0.0 4.6e-06 27.1 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 CBZ32794.1 - 0.16 10.9 0.0 0.26 10.2 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase SAM35 PF10806.8 CBZ32795.1 - 0.017 15.3 0.1 0.039 14.2 0.1 1.5 1 0 0 1 1 1 0 SAM35, subunit of SAM coomplex FAM76 PF16046.5 CBZ32795.1 - 4.9 6.4 12.8 0.41 10.0 1.0 2.9 3 0 0 3 3 3 0 FAM76 protein Pkinase PF00069.25 CBZ32796.1 - 3.7e-63 213.4 0.0 8.8e-56 189.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32796.1 - 3.5e-35 121.5 0.0 5.5e-33 114.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ32796.1 - 0.0012 17.7 3.0 0.0045 15.8 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 CBZ32796.1 - 0.097 12.0 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SHMT PF00464.19 CBZ32798.1 - 1.3e-173 577.2 0.0 1.6e-173 576.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DUF2529 PF10740.9 CBZ32798.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) DnaJ PF00226.31 CBZ32799.1 - 1.7e-19 69.7 3.5 1.7e-19 69.7 3.5 2.0 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 CBZ32799.1 - 2.7e-12 47.0 24.0 0.00061 20.2 1.2 6.1 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ32799.1 - 0.00031 20.7 6.4 0.49 10.7 0.0 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ32799.1 - 0.00038 20.2 4.3 1.1 9.1 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ32799.1 - 0.00061 19.7 14.2 1.2 9.5 0.7 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ32799.1 - 0.0036 17.6 14.9 0.016 15.5 0.9 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ32799.1 - 0.004 17.8 20.9 0.078 13.6 3.1 4.5 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ32799.1 - 0.02 14.6 0.3 4 7.2 0.0 3.0 3 0 0 3 3 3 0 TPR repeat DUF884 PF05959.11 CBZ32799.1 - 0.032 13.9 0.1 0.067 12.8 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) TPR_6 PF13174.6 CBZ32799.1 - 0.035 14.7 12.2 54 4.7 0.4 7.5 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ32799.1 - 0.1 12.7 17.2 0.45 10.7 0.6 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ32799.1 - 0.12 12.4 2.8 0.31 11.1 0.2 2.9 2 2 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Mhr1 PF12829.7 CBZ32799.1 - 0.13 12.4 0.3 16 5.7 0.1 2.7 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination TPR_17 PF13431.6 CBZ32799.1 - 0.22 12.0 7.0 5 7.7 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat HTH_WhiA PF02650.14 CBZ32799.1 - 0.23 11.8 2.1 0.87 10.0 0.5 2.6 1 1 1 2 2 2 0 WhiA C-terminal HTH domain TPR_14 PF13428.6 CBZ32799.1 - 0.24 12.3 29.1 1.2 10.1 0.2 7.7 5 3 3 9 9 8 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CBZ32799.1 - 0.7 10.4 6.2 2 8.9 0.4 3.0 2 1 1 3 3 3 0 Alkyl sulfatase dimerisation HemY_N PF07219.13 CBZ32799.1 - 1.6 9.0 5.3 18 5.6 0.2 3.4 3 0 0 3 3 3 0 HemY protein N-terminus GRP PF07172.11 CBZ32799.1 - 3.7 8.3 9.0 9.9 6.9 9.0 1.8 1 0 0 1 1 1 0 Glycine rich protein family TPR_20 PF14561.6 CBZ32799.1 - 4.6 7.6 12.1 0.54 10.6 0.2 3.9 3 1 2 5 5 5 0 Tetratricopeptide repeat FA_desaturase PF00487.24 CBZ32800.1 - 1.2e-35 123.5 12.1 1.2e-35 123.5 12.1 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBZ32800.1 - 0.004 17.3 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ALG11_N PF15924.5 CBZ32800.1 - 0.055 13.5 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 ALG11 mannosyltransferase N-terminus DLIC PF05783.11 CBZ32801.1 - 0.064 12.1 0.0 0.3 9.9 0.1 2.0 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 CBZ32801.1 - 0.11 12.5 0.0 9.7 6.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NAD_binding_5 PF07994.12 CBZ32803.1 - 1.8e-110 369.4 0.0 2e-110 369.2 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CBZ32803.1 - 2.6e-44 149.9 0.1 4.1e-44 149.3 0.1 1.3 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase UPF0004 PF00919.20 CBZ32803.1 - 0.04 14.0 1.4 5.4 7.1 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized protein family UPF0004 tRNA-synt_1b PF00579.25 CBZ32804.1 - 2.8e-53 181.2 0.0 2e-47 161.9 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (W and Y) AAA_lid_2 PF17863.1 CBZ32804.1 - 0.31 10.9 2.0 8 6.4 0.0 3.3 3 0 0 3 3 3 0 AAA lid domain EMP24_GP25L PF01105.24 CBZ32806.1 - 1.2e-22 80.7 0.1 1.5e-22 80.4 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Galactosyl_T PF01762.21 CBZ32808.1 - 0.0013 18.6 1.0 0.0061 16.4 0.0 2.6 3 1 0 3 3 3 1 Galactosyltransferase Pkinase PF00069.25 CBZ32809.1 - 1.5e-64 217.9 0.0 1.9e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32809.1 - 7.5e-44 150.0 0.0 9.9e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ32809.1 - 1.9e-06 27.4 0.2 2.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ32809.1 - 0.00025 19.9 0.0 0.00045 19.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase WD40 PF00400.32 CBZ32811.1 - 4.7e-05 24.1 17.2 10 7.2 0.1 9.1 10 0 0 10 10 10 3 WD domain, G-beta repeat Phage_portal PF04860.12 CBZ32811.1 - 0.036 13.3 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Phage portal protein AKNA PF12443.8 CBZ32811.1 - 0.062 13.9 0.3 0.26 11.9 0.3 2.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor MetOD2 PF18548.1 CBZ32811.1 - 0.61 10.2 6.1 4 7.6 0.6 3.0 2 0 0 2 2 2 0 Metanogen output domain 2 Mt_ATP-synt_D PF05873.12 CBZ32811.1 - 3.2 7.6 6.5 3.8 7.3 0.0 3.4 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) LMBR1 PF04791.16 CBZ32811.1 - 9.1 5.1 11.3 0.51 9.2 4.4 2.2 2 0 0 2 2 2 0 LMBR1-like membrane protein C2 PF00168.30 CBZ32812.1 - 1.8e-07 31.4 0.0 0.0027 18.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain Vac14_Fig4_bd PF11916.8 CBZ32813.1 - 4e-47 160.2 2.8 8.2e-47 159.2 2.8 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CBZ32813.1 - 2.8e-08 34.3 0.0 6.2e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CBZ32813.1 - 0.013 15.7 0.0 0.013 15.7 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat Cnd1 PF12717.7 CBZ32813.1 - 0.093 12.8 0.0 0.54 10.3 0.0 2.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 MPC PF03650.13 CBZ32814.1 - 1.6e-14 54.0 0.1 2e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MalF_P2 PF14785.6 CBZ32815.1 - 0.058 13.4 0.1 0.17 11.9 0.1 1.8 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain GST_N_3 PF13417.6 CBZ32816.1 - 1.5e-07 31.7 0.0 2.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CBZ32816.1 - 3.2e-07 30.5 0.2 7.2e-07 29.3 0.2 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_N_4 PF17172.4 CBZ32816.1 - 0.011 16.5 0.0 0.05 14.4 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 CBZ32816.1 - 0.058 13.7 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Syja_N PF02383.18 CBZ32817.1 - 8.2e-27 94.4 0.0 1.2e-26 93.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain CENP-T_C PF15511.6 CBZ32818.1 - 6.3e-07 29.5 0.1 1.1e-06 28.8 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBZ32818.1 - 4.6e-05 23.6 0.9 5.8e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CBZ32818.1 - 0.00017 21.7 0.1 0.0003 20.9 0.1 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CBZ32818.1 - 0.00065 19.7 0.0 0.00082 19.3 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ32818.1 - 0.0023 18.3 3.2 0.0048 17.3 3.2 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ32818.1 - 0.0096 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Ribosomal_S17e PF00833.18 CBZ32818.1 - 0.041 13.8 0.7 0.048 13.6 0.7 1.1 1 0 0 1 1 1 0 Ribosomal S17 Ly-6_related PF06579.12 CBZ32818.1 - 0.068 13.4 0.6 0.085 13.1 0.6 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein DUF4400 PF14348.6 CBZ32818.1 - 0.088 12.3 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) PCP_red PF08369.10 CBZ32818.1 - 0.16 12.2 2.1 0.21 11.8 0.3 2.1 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit RhoGEF67_u1 PF16615.5 CBZ32819.1 - 0.53 10.8 3.1 0.67 10.5 1.3 2.0 2 0 0 2 2 2 0 Unstructured region one on RhoGEF 6 and 7 GDA1_CD39 PF01150.17 CBZ32820.1 - 7.9e-81 271.9 0.0 1e-80 271.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CBZ32820.1 - 0.0061 16.0 0.0 0.0089 15.5 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Lysine_decarbox PF03641.14 CBZ32821.1 - 8.5e-24 84.1 0.1 1.8e-23 83.1 0.1 1.5 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CBZ32821.1 - 3.6e-08 33.1 0.0 7.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 SLOG cluster4 family MSP1b PF03429.13 CBZ32821.1 - 0.058 11.5 0.0 0.08 11.0 0.0 1.2 1 0 0 1 1 1 0 Major surface protein 1B NAD_binding_1 PF00175.21 CBZ32822.1 - 1.7e-28 99.4 0.0 2.7e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBZ32822.1 - 1.1e-25 89.9 0.0 1.8e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBZ32822.1 - 3.9e-07 30.3 0.0 3e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain MIF4G PF02854.19 CBZ32823.1 - 2.4e-23 82.9 1.3 4.4e-23 82.1 1.3 1.5 1 0 0 1 1 1 1 MIF4G domain CRM1_C PF08767.11 CBZ32823.1 - 0.0017 17.6 0.0 0.005 16.1 0.0 1.8 1 0 0 1 1 1 1 CRM1 C terminal IMS PF00817.20 CBZ32823.1 - 0.038 14.0 0.1 0.44 10.5 0.1 2.4 1 1 0 1 1 1 0 impB/mucB/samB family E_Pc_C PF06752.12 CBZ32824.1 - 0.0093 16.1 2.3 0.023 14.8 2.3 1.7 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus CCDC-167 PF15188.6 CBZ32824.1 - 0.14 12.5 1.7 0.4 11.0 0.7 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 EF-hand_like PF09279.11 CBZ32825.1 - 0.13 12.8 5.3 10 6.7 0.3 4.0 3 1 2 5 5 5 0 Phosphoinositide-specific phospholipase C, efhand-like AAA_2 PF07724.14 CBZ32826.1 - 4.3e-40 137.6 1.8 1.7e-31 109.7 0.8 2.8 1 1 1 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CBZ32826.1 - 1.2e-13 51.6 0.0 6.3e-06 26.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ32826.1 - 6.6e-09 35.9 0.3 1.9e-05 24.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ32826.1 - 6e-06 26.6 0.0 0.00029 21.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 CBZ32826.1 - 1.6e-05 24.1 0.1 0.0019 17.3 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain TniB PF05621.11 CBZ32826.1 - 3.3e-05 23.4 0.2 0.0029 17.0 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein ClpB_D2-small PF10431.9 CBZ32826.1 - 6.2e-05 23.0 0.6 0.00034 20.6 0.0 2.4 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_18 PF13238.6 CBZ32826.1 - 6.4e-05 23.5 0.2 0.00021 21.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CBZ32826.1 - 8.8e-05 22.0 0.1 0.0021 17.5 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CBZ32826.1 - 0.0002 21.8 0.3 0.00062 20.2 0.3 1.7 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 CBZ32826.1 - 0.00074 18.8 1.1 0.0011 18.3 0.0 1.8 2 1 0 2 2 2 1 TIP49 P-loop domain NTPase_1 PF03266.15 CBZ32826.1 - 0.00095 19.1 0.9 0.63 9.9 0.0 2.6 2 0 0 2 2 2 2 NTPase RuvB_N PF05496.12 CBZ32826.1 - 0.0014 18.4 0.1 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DEAD PF00270.29 CBZ32826.1 - 0.0015 18.3 0.1 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 CBZ32826.1 - 0.0042 17.1 0.1 2.3 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CBZ32826.1 - 0.0064 16.2 0.6 0.32 10.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ32826.1 - 0.0076 16.4 0.0 0.023 14.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 CBZ32826.1 - 0.011 15.7 0.0 0.035 14.1 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CBZ32826.1 - 0.017 15.3 0.1 0.13 12.5 0.0 2.4 2 1 1 3 3 3 0 AAA domain Sigma54_activat PF00158.26 CBZ32826.1 - 0.018 14.8 0.0 0.058 13.1 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CBZ32826.1 - 0.019 14.2 0.0 0.058 12.7 0.0 1.8 1 1 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 CBZ32826.1 - 0.026 14.9 0.7 0.09 13.1 0.7 1.9 1 1 0 1 1 1 0 AAA domain CPT PF07931.12 CBZ32826.1 - 0.031 14.1 0.2 0.26 11.1 0.0 2.5 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein IstB_IS21 PF01695.17 CBZ32826.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CBZ32826.1 - 0.042 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 CBZ32826.1 - 0.043 13.3 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CBZ32826.1 - 0.051 14.1 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 CBZ32826.1 - 0.072 13.0 0.1 3 7.8 0.0 2.7 2 1 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 CBZ32826.1 - 0.13 12.7 0.0 0.87 10.0 0.0 2.3 2 1 0 2 2 2 0 RNA helicase AAA_17 PF13207.6 CBZ32826.1 - 1.8 9.0 5.9 4.1 7.8 0.2 3.8 3 1 1 4 4 4 0 AAA domain FMO-like PF00743.19 CBZ32827.1 - 6.1e-27 94.2 0.1 2.9e-22 78.8 0.1 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CBZ32827.1 - 2.7e-14 53.1 0.0 1.1e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBZ32827.1 - 7e-10 38.6 0.7 1.4e-05 24.5 0.1 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CBZ32827.1 - 4.8e-08 32.5 0.3 7.2e-06 25.4 0.2 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CBZ32827.1 - 3.9e-06 27.0 0.0 1.5e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CBZ32827.1 - 0.0012 19.4 0.0 1.4 9.5 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF1490 PF07371.12 CBZ32827.1 - 0.0016 18.5 2.4 0.002 18.2 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1490) NAD_binding_9 PF13454.6 CBZ32827.1 - 0.0046 17.0 0.2 0.063 13.3 0.2 2.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding IlvN PF07991.12 CBZ32827.1 - 0.0076 15.8 0.0 0.88 9.1 0.0 2.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 CBZ32827.1 - 0.014 14.7 0.1 5.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CBZ32827.1 - 0.026 13.2 0.1 0.041 12.6 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 CBZ32827.1 - 0.053 12.6 0.9 0.19 10.8 0.9 2.1 1 1 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 CBZ32827.1 - 0.081 12.1 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 CBZ32827.1 - 0.18 10.9 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A YlqD PF11068.8 CBZ32828.1 - 0.23 11.8 1.1 0.41 11.0 1.1 1.3 1 0 0 1 1 1 0 YlqD protein Mito_carr PF00153.27 CBZ32829.1 - 1.5e-42 143.5 1.2 5.2e-15 55.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.29 CBZ32830.1 - 6.8e-42 143.2 0.1 1.4e-41 142.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ32830.1 - 1.5e-27 96.1 7.3 3e-25 88.7 0.1 4.3 3 1 1 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ32830.1 - 0.00045 20.3 0.1 0.0048 16.9 0.0 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit zf-CCCH PF00642.24 CBZ32831.1 - 8.3e-05 22.4 6.6 8.3e-05 22.4 6.6 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) oligo_HPY PF08352.12 CBZ32831.1 - 0.48 11.0 6.6 0.97 10.0 1.2 2.5 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-CCCH_4 PF18044.1 CBZ32833.1 - 7.3e-05 22.5 1.8 0.00012 21.8 1.8 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CBZ32833.1 - 0.00017 21.4 4.1 0.00028 20.7 4.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ32833.1 - 0.077 13.1 2.0 0.13 12.3 2.0 1.4 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ32833.1 - 0.42 11.2 2.7 0.79 10.3 2.7 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PP2C PF00481.21 CBZ32834.1 - 4.8e-64 216.5 0.0 8.7e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ32834.1 - 0.0015 18.2 0.0 0.0038 16.9 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C DUF3276 PF11680.8 CBZ32834.1 - 0.06 13.5 2.4 0.074 13.2 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) Pkinase PF00069.25 CBZ32835.1 - 1.1e-43 149.5 0.0 2.5e-43 148.3 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32835.1 - 3.5e-14 52.7 0.0 8.6e-14 51.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBZ32835.1 - 3.4e-05 23.9 0.3 0.0025 17.8 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBZ32835.1 - 0.0039 16.8 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 CBZ32835.1 - 0.22 10.5 0.1 0.35 9.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MscS_porin PF12795.7 CBZ32836.1 - 0.08 12.5 6.6 0.29 10.6 0.3 2.9 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Cyt-b5 PF00173.28 CBZ32837.1 - 1.4e-06 28.3 0.0 2.4e-06 27.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Adeno_E3_CR2 PF02439.15 CBZ32837.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Pkr1 PF08636.10 CBZ32838.1 - 7.1 6.9 7.0 0.58 10.3 1.5 1.9 2 0 0 2 2 2 0 ER protein Pkr1 Metallophos PF00149.28 CBZ32841.1 - 2.4e-31 109.8 0.0 3.1e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.32 CBZ32843.1 - 1.8e-09 38.1 4.1 0.0027 18.5 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat MYEOV2 PF15004.6 CBZ32843.1 - 0.097 13.1 0.0 0.29 11.6 0.0 1.8 1 0 0 1 1 1 0 Myeloma-overexpressed-like tRNA-synt_2 PF00152.20 CBZ32844.1 - 1.3e-75 254.4 0.0 2.2e-75 253.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBZ32844.1 - 1.9e-13 50.2 0.0 4.6e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBZ32844.1 - 1.5e-06 27.9 0.0 0.013 15.0 0.0 2.8 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 CBZ32844.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain FlxA PF14282.6 CBZ32844.1 - 0.25 11.3 4.2 0.07 13.1 1.1 1.6 2 0 0 2 2 2 0 FlxA-like protein YabA PF06156.13 CBZ32844.1 - 1.7 9.3 3.4 1 10.0 1.0 1.9 2 0 0 2 2 2 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 CBZ32844.1 - 9 6.6 7.2 1.8 8.8 3.4 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FAE1_CUT1_RppA PF08392.12 CBZ32845.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein EZH2_N PF18601.1 CBZ32847.1 - 0.06 13.7 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 EZH2 N-terminal domain Rtt102p PF09510.10 CBZ32847.1 - 6.1 7.1 6.2 6 7.1 1.3 2.2 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein RPA_C PF08784.11 CBZ32848.1 - 2.9e-11 43.9 2.3 3.2e-11 43.8 0.3 2.1 3 0 0 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 CBZ32848.1 - 1.7e-09 37.5 0.0 3.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PaaX PF07848.12 CBZ32848.1 - 0.091 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 PaaX-like protein GntR PF00392.21 CBZ32848.1 - 0.098 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family PPR_2 PF13041.6 CBZ32849.1 - 0.0019 18.4 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 PPR repeat family FERM_f0 PF16511.5 CBZ32849.1 - 0.0078 16.5 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM PPR_3 PF13812.6 CBZ32849.1 - 0.032 14.3 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Prefoldin_2 PF01920.20 CBZ32849.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Prefoldin subunit PPR_2 PF13041.6 CBZ32850.1 - 1.8e-07 31.2 0.5 0.013 15.7 0.0 2.3 2 0 0 2 2 2 2 PPR repeat family PPR_long PF17177.4 CBZ32850.1 - 0.0014 18.0 0.0 0.28 10.5 0.0 2.1 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CBZ32850.1 - 0.0066 16.5 0.1 0.21 11.7 0.1 2.2 2 0 0 2 2 2 1 Pentatricopeptide repeat domain FERM_f0 PF16511.5 CBZ32850.1 - 0.024 14.9 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM RPM2 PF08579.11 CBZ32850.1 - 0.032 14.6 0.0 0.046 14.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Prefoldin_2 PF01920.20 CBZ32850.1 - 0.034 14.1 0.5 0.073 13.0 0.0 1.7 2 0 0 2 2 2 0 Prefoldin subunit DUF4241 PF14025.6 CBZ32850.1 - 0.06 13.6 0.7 0.27 11.5 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4241) DUF3081 PF11280.8 CBZ32851.1 - 0.015 15.1 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Ecotin PF03974.13 CBZ32852.1 - 3.5e-39 133.5 0.0 4.1e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Ecotin Abhydrolase_3 PF07859.13 CBZ32854.1 - 1e-11 45.1 0.1 2.6e-11 43.8 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 CBZ32854.1 - 2.3e-09 36.7 0.4 8.5e-09 34.8 0.1 1.9 1 1 0 2 2 2 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CBZ32854.1 - 4.7e-06 27.4 0.4 1.4e-05 25.8 0.1 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBZ32854.1 - 2.4e-05 23.9 0.2 0.052 13.0 0.1 2.9 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CBZ32854.1 - 0.032 13.9 0.1 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF4566 PF15130.6 CBZ32854.1 - 0.092 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) Abhydrolase_3 PF07859.13 CBZ32855.1 - 1.4e-11 44.7 0.0 3.2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CBZ32855.1 - 6.4e-09 35.2 0.0 1.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CBZ32855.1 - 1.4e-05 24.7 0.1 0.057 12.9 0.1 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CBZ32855.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PseudoU_synth_2 PF00849.22 CBZ32858.1 - 1.5e-17 64.2 0.4 3.1e-08 33.9 0.1 2.8 2 1 0 2 2 2 2 RNA pseudouridylate synthase Ribosomal_60s PF00428.19 CBZ32859.1 - 3.3e-10 40.4 12.8 4e-10 40.1 12.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arg_repressor_C PF02863.18 CBZ32859.1 - 0.0059 16.4 0.3 0.0059 16.4 0.3 2.1 2 1 0 2 2 2 1 Arginine repressor, C-terminal domain Ribosomal_60s PF00428.19 CBZ32860.1 - 1.6e-21 76.7 14.1 1.9e-21 76.4 14.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Arg_repressor_C PF02863.18 CBZ32860.1 - 0.0091 15.8 0.3 0.0091 15.8 0.3 2.4 2 1 1 3 3 3 1 Arginine repressor, C-terminal domain Asparaginase PF00710.20 CBZ32861.1 - 1e-52 178.5 0.0 1.7e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CBZ32861.1 - 7.3e-23 81.0 0.0 1.2e-22 80.3 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain DUF282 PF03380.14 CBZ32861.1 - 0.11 12.5 2.0 9.9 6.2 0.0 3.1 3 0 0 3 3 3 0 Caenorhabditis protein of unknown function, DUF282 Zf_RING PF16744.5 CBZ32861.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger PPR_2 PF13041.6 CBZ32863.1 - 0.004 17.3 0.0 0.067 13.4 0.0 2.4 1 1 1 2 2 2 2 PPR repeat family PPR_3 PF13812.6 CBZ32863.1 - 0.17 12.0 0.0 0.7 10.0 0.0 1.9 2 0 0 2 2 2 0 Pentatricopeptide repeat domain FR47 PF08445.10 CBZ32865.1 - 0.083 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein TFIIF_alpha PF05793.12 CBZ32866.1 - 0.0047 15.6 2.3 0.006 15.2 2.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GRA6 PF05084.13 CBZ32866.1 - 0.43 10.5 3.9 0.78 9.7 3.9 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) AAA PF00004.29 CBZ32869.1 - 2.6e-38 131.4 0.0 4.3e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ32869.1 - 3.6e-12 45.9 0.0 8.5e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CBZ32869.1 - 4e-09 36.3 0.0 1.3e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 CBZ32869.1 - 1.1e-05 25.5 0.1 7.6e-05 22.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBZ32869.1 - 2.4e-05 24.2 0.0 5.1e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBZ32869.1 - 0.00018 21.8 0.1 0.0037 17.6 0.0 2.8 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ32869.1 - 0.00085 19.7 3.2 0.013 15.8 0.2 3.5 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 CBZ32869.1 - 0.0035 16.6 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CBZ32869.1 - 0.0061 16.0 0.1 0.013 14.9 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBZ32869.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 CBZ32869.1 - 0.009 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CBZ32869.1 - 0.024 15.2 0.0 0.053 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBZ32869.1 - 0.029 13.9 0.2 0.6 9.7 0.0 2.4 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ32869.1 - 0.046 13.9 0.2 0.21 11.8 0.0 2.2 2 1 0 2 2 1 0 AAA domain DUF815 PF05673.13 CBZ32869.1 - 0.052 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 CBZ32869.1 - 0.061 12.7 0.0 2.8 7.3 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein AAA_14 PF13173.6 CBZ32869.1 - 0.072 13.1 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CBZ32869.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 CBZ32869.1 - 0.14 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CBZ32869.1 - 0.2 11.4 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ecotin PF03974.13 CBZ32870.1 - 0.0032 17.4 0.0 0.0036 17.3 0.0 1.1 1 0 0 1 1 1 1 Ecotin Ecotin PF03974.13 CBZ32871.1 - 1.6e-37 128.2 0.1 3e-37 127.3 0.1 1.5 1 0 0 1 1 1 1 Ecotin HMMR_N PF15905.5 CBZ32875.1 - 0.0018 17.8 6.2 0.0018 17.8 6.2 3.2 4 0 0 4 4 4 1 Hyaluronan mediated motility receptor N-terminal RasGAP_C PF03836.15 CBZ32875.1 - 0.62 10.2 5.1 0.26 11.4 1.0 2.4 3 0 0 3 3 3 0 RasGAP C-terminus Sipho_Gp157 PF05565.11 CBZ32875.1 - 0.95 9.5 9.9 0.1 12.6 3.9 2.4 2 0 0 2 2 2 0 Siphovirus Gp157 DUF3456 PF11938.8 CBZ32875.1 - 1.4 9.5 4.7 0.88 10.1 2.1 1.9 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP SPC22 PF04573.12 CBZ32877.1 - 1.8e-16 60.1 0.3 7.1e-11 41.9 0.0 3.1 3 0 0 3 3 3 3 Signal peptidase subunit MDH PF02315.16 CBZ32878.1 - 0.0035 17.4 0.1 0.0076 16.3 0.1 1.5 1 0 0 1 1 1 1 Methanol dehydrogenase beta subunit DUF4429 PF14472.6 CBZ32878.1 - 0.0068 17.0 0.8 0.9 10.2 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4429) FAM183 PF14886.6 CBZ32878.1 - 0.01 16.5 0.2 0.04 14.6 0.2 2.2 1 1 0 1 1 1 0 FAM183A and FAM183B related Fez1 PF06818.15 CBZ32879.1 - 0.022 15.2 4.4 0.077 13.4 4.4 1.9 1 0 0 1 1 1 0 Fez1 Filament PF00038.21 CBZ32879.1 - 3.9 7.0 9.8 8.6 5.8 0.9 2.4 2 0 0 2 2 2 0 Intermediate filament protein ChapFlgA_N PF17656.1 CBZ32880.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 FlgA N-terminal domain CRAL_TRIO PF00650.20 CBZ32881.1 - 6.2e-16 58.5 0.0 2.2e-14 53.5 0.0 2.6 2 1 0 2 2 2 1 CRAL/TRIO domain DUF842 PF05811.13 CBZ32883.1 - 2.5 7.8 9.9 0.54 10.0 6.1 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF842) Kelch_4 PF13418.6 CBZ32884.1 - 2.6e-21 75.4 1.6 4.4e-06 26.6 0.0 6.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ32884.1 - 1.8e-19 69.3 1.8 4.4e-05 23.4 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CBZ32884.1 - 8.9e-15 54.4 1.7 4.5e-07 29.9 0.1 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CBZ32884.1 - 1.2e-12 47.2 3.6 0.00022 21.1 0.1 4.3 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 CBZ32884.1 - 3.3e-12 46.3 12.5 0.00035 20.8 0.0 6.7 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ32884.1 - 1.5e-09 37.2 5.8 0.0046 16.5 0.1 4.1 3 0 0 3 3 3 3 Kelch motif Ipi1_N PF12333.8 CBZ32887.1 - 2.9e-05 24.6 2.0 0.017 15.7 0.1 3.8 2 1 1 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation V-ATPase_H_C PF11698.8 CBZ32887.1 - 0.068 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 V-ATPase subunit H HEAT PF02985.22 CBZ32887.1 - 0.27 11.6 1.5 1.2 9.5 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat Cmc1 PF08583.10 CBZ32888.1 - 0.0034 17.4 0.9 0.0034 17.4 0.9 1.9 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like RseA_C PF03873.13 CBZ32888.1 - 0.19 12.0 0.0 0.55 10.5 0.0 1.8 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain UPF0203 PF05254.12 CBZ32888.1 - 0.24 11.7 3.1 0.15 12.3 0.6 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) tRNA-synt_2c PF01411.19 CBZ32889.1 - 0.0026 16.3 0.0 0.0035 15.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CBZ32889.1 - 0.0096 16.0 0.1 0.042 14.0 0.0 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain TPR_12 PF13424.6 CBZ32891.1 - 0.096 13.0 1.9 0.53 10.6 0.9 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 CBZ32892.1 - 2.6e-05 23.7 3.4 1.1 8.4 0.0 3.9 3 1 0 3 3 3 3 FAD binding domain Pyr_redox PF00070.27 CBZ32892.1 - 0.0052 17.3 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBZ32892.1 - 0.0059 16.2 0.3 0.018 14.7 0.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBZ32892.1 - 0.0084 15.4 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CBZ32892.1 - 0.15 11.7 0.0 0.4 10.3 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Methyltransf_16 PF10294.9 CBZ32893.1 - 7e-10 38.9 0.0 2.6e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 CBZ32893.1 - 0.04 13.3 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CBZ32893.1 - 0.047 14.4 0.1 0.17 12.6 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF2871 PF11070.8 CBZ32894.1 - 9.2e-41 139.3 10.1 1.2e-40 138.9 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2871) TMEM174 PF15029.6 CBZ32894.1 - 0.25 11.1 0.7 0.38 10.4 0.7 1.2 1 0 0 1 1 1 0 Transmembrane protein 174 ABC_tran PF00005.27 CBZ32896.1 - 1.2e-51 174.8 0.0 7.7e-29 100.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CBZ32896.1 - 1.2e-42 146.3 60.8 2.5e-30 105.8 24.4 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CBZ32896.1 - 2e-20 73.8 1.9 1.8e-08 34.5 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 CBZ32896.1 - 3.8e-05 24.3 0.0 0.0083 16.8 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 CBZ32896.1 - 5.4e-05 23.2 0.0 0.023 14.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 CBZ32896.1 - 5.7e-05 22.7 0.1 0.29 10.5 0.1 3.8 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ32896.1 - 8.2e-05 22.3 0.7 0.033 13.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CBZ32896.1 - 0.00017 22.1 1.0 0.027 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CBZ32896.1 - 0.0059 16.4 0.0 4.6 6.8 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_30 PF13604.6 CBZ32896.1 - 0.023 14.4 0.0 0.41 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CBZ32896.1 - 0.054 13.1 0.2 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CBZ32896.1 - 0.077 13.1 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CBZ32896.1 - 0.12 12.8 0.0 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 CBZ32896.1 - 0.17 12.3 0.0 1.8 9.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AIG1 PF04548.16 CBZ32896.1 - 0.21 10.9 0.3 0.73 9.1 0.0 1.9 2 0 0 2 2 2 0 AIG1 family LapA_dom PF06305.11 CBZ32896.1 - 0.34 10.8 2.2 1.5 8.7 2.2 2.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 CBZ32897.1 - 9.5e-29 100.6 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32897.1 - 2.2e-14 53.4 0.0 3.2e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ32897.1 - 0.00091 18.6 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ32897.1 - 0.061 13.2 0.0 4.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family KRE9 PF05390.11 CBZ32897.1 - 0.22 12.3 4.0 0.89 10.3 0.2 3.1 3 0 0 3 3 3 0 Yeast cell wall synthesis protein KRE9/KNH1 TFIIA PF03153.13 CBZ32897.1 - 2.2 8.2 13.0 3.4 7.6 13.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4644 PF15486.6 CBZ32899.1 - 0.03 14.1 2.2 0.4 10.4 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) KASH_CCD PF14662.6 CBZ32900.1 - 0.0061 16.4 2.1 0.0061 16.4 2.1 8.6 7 2 3 10 10 10 2 Coiled-coil region of CCDC155 or KASH Pex16 PF08610.10 CBZ32901.1 - 2e-14 53.5 0.0 7.8e-12 45.0 0.0 2.4 2 0 0 2 2 2 2 Peroxisomal membrane protein (Pex16) DPM2 PF07297.12 CBZ32902.1 - 1.2e-17 63.9 1.3 1.6e-17 63.5 1.3 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) GDI PF00996.18 CBZ32903.1 - 5.1e-19 68.1 0.0 6.2e-10 38.2 0.0 2.7 2 1 0 2 2 2 2 GDP dissociation inhibitor Methyltransf_16 PF10294.9 CBZ32903.1 - 5.9e-12 45.7 0.0 1.9e-05 24.4 0.0 2.3 1 1 1 2 2 2 2 Lysine methyltransferase MTS PF05175.14 CBZ32903.1 - 0.012 15.2 0.2 2.2 7.8 0.0 2.7 2 1 1 3 3 3 0 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 CBZ32903.1 - 0.044 13.0 0.0 0.11 11.6 0.0 1.7 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Phe_tRNA-synt_N PF02912.18 CBZ32905.1 - 2.4 8.2 6.6 0.37 10.8 1.3 2.4 2 1 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Nuc_sug_transp PF04142.15 CBZ32906.1 - 2.3e-26 92.7 19.6 4e-25 88.6 19.6 2.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 CBZ32906.1 - 1.3e-05 25.4 28.5 0.0038 17.4 3.9 3.3 3 1 0 3 3 3 2 EamA-like transporter family MFS_1 PF07690.16 CBZ32909.1 - 3.4e-11 42.7 44.8 5.4e-07 28.9 12.6 3.7 2 2 2 4 4 4 4 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ32909.1 - 7.1e-08 31.7 13.1 1.4e-07 30.8 2.6 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter SirB PF04247.12 CBZ32909.1 - 0.18 11.9 4.5 1.3 9.1 0.1 3.1 3 0 0 3 3 3 0 Invasion gene expression up-regulator, SirB Inositol_P PF00459.25 CBZ32910.1 - 3.6e-46 157.9 2.4 3.9e-23 82.3 0.5 2.2 2 0 0 2 2 2 2 Inositol monophosphatase family Mito_carr PF00153.27 CBZ32910.1 - 0.0091 15.9 0.3 0.042 13.8 0.3 2.2 1 0 0 1 1 1 1 Mitochondrial carrier protein SUIM_assoc PF16619.5 CBZ32910.1 - 3.3 7.8 7.0 9 6.5 7.0 1.9 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF5570 PF17731.1 CBZ32910.1 - 5.3 7.2 7.6 1.7 8.7 0.6 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5570) ABC2_membrane PF01061.24 CBZ32911.1 - 3.5e-40 137.7 19.0 5.6e-40 137.0 19.0 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBZ32911.1 - 5.3e-19 69.1 0.0 8.3e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CBZ32911.1 - 0.0018 18.7 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ32911.1 - 0.0061 16.5 0.0 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CBZ32911.1 - 0.0084 16.4 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CBZ32911.1 - 0.028 14.9 0.1 0.045 14.3 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBZ32911.1 - 0.034 13.9 0.9 0.066 12.9 0.9 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBZ32911.1 - 0.04 13.7 0.4 0.089 12.5 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.18 CBZ32911.1 - 0.047 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CBZ32911.1 - 0.095 13.3 0.0 0.27 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 CBZ32911.1 - 0.097 13.1 0.0 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 CBZ32911.1 - 0.098 12.6 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.19 CBZ32911.1 - 0.11 11.9 0.0 9.7 5.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CBZ32911.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase NB-ARC PF00931.22 CBZ32911.1 - 0.15 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_21 PF13304.6 CBZ32911.1 - 0.15 11.8 0.0 18 5.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 CBZ32911.1 - 0.18 11.5 0.5 0.37 10.5 0.5 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 CBZ32911.1 - 0.27 10.3 16.6 0.015 14.5 11.2 1.6 2 0 0 2 2 2 0 ABC-2 family transporter protein HEAT PF02985.22 CBZ32914.1 - 1.2e-19 68.7 24.7 0.0013 18.9 0.0 10.5 11 0 0 11 11 11 8 HEAT repeat HEAT_2 PF13646.6 CBZ32914.1 - 5.3e-18 65.2 22.1 8e-06 26.2 1.8 7.1 4 2 3 7 7 7 6 HEAT repeats CLASP_N PF12348.8 CBZ32914.1 - 7.7e-05 22.4 0.5 0.28 10.7 0.1 3.8 2 2 1 3 3 3 2 CLASP N terminal Adaptin_N PF01602.20 CBZ32914.1 - 8.8e-05 21.3 4.2 0.018 13.7 0.3 2.7 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 CBZ32914.1 - 0.00079 19.5 4.8 0.77 9.8 0.2 4.5 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Nipped-B_C PF12830.7 CBZ32914.1 - 0.091 12.7 0.6 20 5.1 0.0 3.0 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus OCIA PF07051.11 CBZ32914.1 - 0.14 12.2 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) Cohesin_HEAT PF12765.7 CBZ32914.1 - 0.17 12.2 2.4 0.48 10.8 0.1 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.23 CBZ32914.1 - 0.25 11.4 5.1 10 6.3 0.1 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat EF-hand_9 PF14658.6 CBZ32915.1 - 3e-09 37.1 0.0 0.031 14.6 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CBZ32915.1 - 2.6e-08 33.6 0.0 0.073 12.9 0.0 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 CBZ32915.1 - 3e-08 34.0 0.0 9.6e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ32915.1 - 7e-07 28.7 0.0 0.15 12.0 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBZ32915.1 - 0.00018 20.8 0.0 1.9 8.2 0.0 3.4 3 0 0 3 3 3 2 EF hand DUF2087 PF09860.9 CBZ32915.1 - 0.01 16.0 0.0 0.79 9.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) Retrotran_gag_2 PF14223.6 CBZ32915.1 - 0.04 13.6 0.1 10 5.8 0.0 2.5 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF2267 PF10025.9 CBZ32915.1 - 0.045 14.0 0.4 4.2 7.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) MAP65_ASE1 PF03999.12 CBZ32916.1 - 6.3e-08 31.8 3.6 6.3e-08 31.8 3.6 2.4 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Nup88 PF10168.9 CBZ32916.1 - 0.61 7.8 4.0 1.1 7.0 4.0 1.3 1 0 0 1 1 1 0 Nuclear pore component Evr1_Alr PF04777.13 CBZ32917.1 - 1.2e-21 77.0 0.8 3.9e-21 75.4 0.8 1.9 1 0 0 1 1 1 1 Erv1 / Alr family Prok-E2_E PF14462.6 CBZ32917.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family E ThiF PF00899.21 CBZ32918.1 - 3.5e-49 167.4 0.0 5.1e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family PglD_N PF17836.1 CBZ32918.1 - 0.0018 18.9 0.0 0.0039 17.8 0.0 1.6 1 0 0 1 1 1 1 PglD N-terminal domain 2-Hacid_dh_C PF02826.19 CBZ32918.1 - 0.0036 16.7 0.0 0.0082 15.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CBZ32918.1 - 0.012 15.3 0.1 0.051 13.2 0.1 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 CBZ32918.1 - 0.013 15.8 0.1 0.082 13.2 0.0 2.3 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 CBZ32918.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 CBZ32918.1 - 0.045 13.0 0.3 0.045 13.0 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 CBZ32918.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Peptidase_M66 PF10462.9 CBZ32918.1 - 0.08 11.9 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Fer4_17 PF13534.6 CBZ32920.1 - 5.2e-08 33.3 10.3 1.1e-06 29.0 1.6 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 CBZ32920.1 - 1.8e-07 31.5 0.5 0.00033 21.0 0.4 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBZ32920.1 - 0.00024 21.1 3.8 0.0006 19.9 3.8 1.6 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBZ32920.1 - 0.0084 16.7 2.4 0.026 15.1 2.4 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBZ32920.1 - 0.027 14.6 4.9 0.038 14.2 1.2 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 CBZ32920.1 - 0.051 14.1 1.0 0.051 14.1 1.0 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain ELFV_dehydrog PF00208.21 CBZ32921.1 - 3.7e-49 167.6 0.0 6.5e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CBZ32921.1 - 5.3e-16 57.4 0.0 1.3e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase CLP1_N PF16573.5 CBZ32921.1 - 0.11 12.8 0.0 0.33 11.2 0.0 1.8 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor Clathrin_H_link PF13838.6 CBZ32921.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 Clathrin-H-link polyprenyl_synt PF00348.17 CBZ32922.1 - 9.7e-60 201.8 0.0 1.2e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SKIP_SNW PF02731.15 CBZ32923.1 - 3.9e-08 33.1 2.4 3.9e-08 33.1 2.4 2.6 1 1 1 2 2 2 1 SKIP/SNW domain Mit_KHE1 PF10173.9 CBZ32923.1 - 0.18 11.9 0.9 0.39 10.8 0.5 1.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF572 PF04502.13 CBZ32923.1 - 2.2 7.8 13.5 3.9 7.0 13.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DOR PF14839.6 CBZ32923.1 - 5.1 7.0 10.1 12 5.8 10.1 1.7 1 0 0 1 1 1 0 DOR family GREB1 PF15782.5 CBZ32923.1 - 5.5 4.0 5.8 7.4 3.5 5.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AhpC-TSA PF00578.21 CBZ32926.1 - 5.7e-12 45.6 0.0 7.9e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CBZ32926.1 - 1.3e-11 44.1 0.1 2.4e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CBZ32926.1 - 4.2e-06 26.6 0.0 4.9e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CBZ32928.1 - 7.8e-38 129.2 0.0 1e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ32928.1 - 1.1e-16 60.8 0.0 1.4e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBZ32928.1 - 3.3e-13 49.3 0.7 6.3e-13 48.3 0.1 1.8 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin TFIIB_C_1 PF18542.1 CBZ32929.1 - 1.5e-41 140.3 1.7 1.5e-41 140.3 1.7 2.0 3 0 0 3 3 3 1 Transcription factor IIB C-terminal module 1 TF_Zn_Ribbon PF08271.12 CBZ32929.1 - 1.5e-05 24.4 1.4 2.9e-05 23.5 1.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Lar_restr_allev PF14354.6 CBZ32929.1 - 0.13 12.7 0.4 0.3 11.5 0.4 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 CBZ32929.1 - 0.2 11.1 1.7 0.88 9.1 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain CobS PF02654.15 CBZ32930.1 - 0.73 10.0 8.7 0.72 10.0 0.2 3.5 3 0 0 3 3 3 0 Cobalamin-5-phosphate synthase cNMP_binding PF00027.29 CBZ32931.1 - 0.00022 21.2 0.0 0.01 15.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 CBZ32932.1 - 1.3e-57 195.2 0.0 2.3e-57 194.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32932.1 - 5.2e-40 137.4 0.0 9.1e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 CBZ32932.1 - 2e-29 101.5 0.7 8.5e-15 54.6 0.1 3.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 CBZ32932.1 - 2.6e-08 33.6 0.0 7.1e-07 28.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PAS PF00989.25 CBZ32932.1 - 5e-07 29.7 0.0 1.5e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CBZ32932.1 - 0.00021 21.5 0.0 0.00086 19.5 0.0 2.1 1 0 0 1 1 1 1 PAS domain RIO1 PF01163.22 CBZ32932.1 - 0.057 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Ribosomal_60s PF00428.19 CBZ32933.1 - 2.5e-23 82.5 11.7 3.2e-23 82.1 11.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage-MuB_C PF09077.11 CBZ32933.1 - 0.036 13.9 3.8 0.07 13.0 3.8 1.7 1 1 0 1 1 1 0 Mu B transposition protein, C terminal Ribosomal_60s PF00428.19 CBZ32934.1 - 6.3e-23 81.2 12.6 7.9e-23 80.9 12.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage-MuB_C PF09077.11 CBZ32934.1 - 0.052 13.4 4.5 0.12 12.3 4.5 1.8 1 1 0 1 1 1 0 Mu B transposition protein, C terminal DUF4366 PF14283.6 CBZ32934.1 - 0.1 12.6 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) RhoGAP PF00620.27 CBZ32935.1 - 5.3e-11 42.6 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 CBZ32935.1 - 3.9e-09 36.4 0.0 7.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DnaJ PF00226.31 CBZ32936.1 - 2.9e-26 91.4 1.6 4.5e-26 90.7 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CBZ32936.1 - 4.8e-18 65.7 0.0 2.8e-17 63.2 0.0 2.0 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CBZ32936.1 - 3.8e-07 30.4 12.7 7.1e-07 29.5 12.7 1.4 1 0 0 1 1 1 1 DnaJ central domain SabA_adhesion PF18304.1 CBZ32936.1 - 0.24 10.6 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 SabA N-terminal extracellular adhesion domain Anti-TRAP PF15777.5 CBZ32936.1 - 3.3 7.7 15.2 0.17 11.9 3.2 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Nucleoside_tran PF01733.18 CBZ32937.1 - 3.8e-34 118.5 2.9 3.8e-34 118.5 2.9 2.2 2 1 0 2 2 2 1 Nucleoside transporter COX7a PF02238.15 CBZ32937.1 - 0.22 12.0 0.0 0.22 12.0 0.0 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII COX7a PF02238.15 CBZ32938.1 - 0.007 16.7 0.1 0.007 16.7 0.1 2.0 2 1 0 2 2 2 1 Cytochrome c oxidase subunit VII PrgI PF12666.7 CBZ32938.1 - 0.014 16.1 0.0 0.016 15.9 0.0 1.1 1 0 0 1 1 1 0 PrgI family protein Nucleoside_tran PF01733.18 CBZ32939.1 - 2.3e-13 50.2 0.4 2.7e-13 50.0 0.4 1.1 1 0 0 1 1 1 1 Nucleoside transporter MFS_Mycoplasma PF07672.13 CBZ32939.1 - 0.035 13.4 0.8 0.041 13.2 0.8 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter COX7a PF02238.15 CBZ32940.1 - 0.016 15.6 0.1 0.016 15.6 0.1 1.9 2 1 0 2 2 2 0 Cytochrome c oxidase subunit VII PrgI PF12666.7 CBZ32940.1 - 0.035 14.8 0.3 0.045 14.5 0.4 1.3 1 1 0 1 1 1 0 PrgI family protein UFC1 PF08694.11 CBZ32941.1 - 7.9e-79 262.7 0.2 9e-79 262.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 CBZ32941.1 - 0.00063 19.4 0.2 0.00089 18.9 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBZ32941.1 - 0.0085 16.4 0.0 0.01 16.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain SET PF00856.28 CBZ32942.1 - 4.1e-08 33.8 0.0 9.9e-08 32.5 0.0 1.7 2 1 0 2 2 2 1 SET domain MFAP1 PF06991.11 CBZ32945.1 - 9.6 6.0 24.0 0.0076 16.1 10.3 2.4 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing DNA_topoisoIV PF00521.20 CBZ32946.1 - 1.5e-102 343.7 0.0 2.3e-102 343.1 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CBZ32946.1 - 3.1e-31 108.3 1.2 3.1e-31 108.3 1.2 1.7 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CBZ32946.1 - 9e-10 38.3 0.1 2.1e-09 37.1 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CBZ32946.1 - 1.3e-08 35.4 0.0 4e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CBZ32946.1 - 8e-07 29.2 0.0 3e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Toprim domain Dynein_AAA_lid PF17852.1 CBZ32946.1 - 0.18 11.9 1.0 22 5.1 0.1 2.6 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain UCH PF00443.29 CBZ32947.1 - 9.6e-38 130.1 0.0 1.4e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 CBZ32947.1 - 1.2e-10 41.1 0.0 5.5e-05 22.6 0.0 3.1 2 1 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 CBZ32947.1 - 6.2e-08 32.6 0.7 0.012 15.2 0.0 2.6 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CorA PF01544.18 CBZ32948.1 - 9.2e-24 84.3 7.0 3.9e-21 75.6 7.0 2.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SHOCT PF09851.9 CBZ32948.1 - 4.8e-05 23.0 0.2 8.8e-05 22.1 0.2 1.5 1 0 0 1 1 1 1 Short C-terminal domain Macoilin PF09726.9 CBZ32948.1 - 0.092 11.3 4.5 0.17 10.4 4.5 1.3 1 0 0 1 1 1 0 Macoilin family DUF1645 PF07816.11 CBZ32948.1 - 0.48 11.0 22.1 0.23 12.0 15.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1645) MIF4G PF02854.19 CBZ32949.1 - 4.2e-10 39.6 0.0 1e-09 38.4 0.0 1.6 1 1 0 1 1 1 1 MIF4G domain Actin PF00022.19 CBZ32950.1 - 2.2e-102 342.7 0.0 3.5e-102 342.1 0.0 1.3 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBZ32950.1 - 0.0036 16.2 0.1 0.16 10.8 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein ATP-synt_C PF00137.21 CBZ32950.1 - 0.044 14.1 0.2 6.7 7.1 0.1 2.5 2 0 0 2 2 2 0 ATP synthase subunit C EF-hand_7 PF13499.6 CBZ32951.1 - 0.19 12.2 0.0 2.1 8.9 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Nnf1 PF03980.14 CBZ32953.1 - 0.64 10.4 5.1 1.3 9.5 1.7 2.6 2 1 0 2 2 2 0 Nnf1 Surfac_D-trimer PF09006.11 CBZ32953.1 - 9.1 6.3 6.4 19 5.3 1.2 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation RabGAP-TBC PF00566.18 CBZ32954.1 - 2.5e-05 24.0 0.2 5.2e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SH3_4 PF06347.13 CBZ32954.1 - 0.17 11.8 0.3 0.44 10.4 0.3 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain 2OG-FeII_Oxy PF03171.20 CBZ32955.1 - 0.0055 17.2 0.0 0.17 12.3 0.0 2.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Actin PF00022.19 CBZ32956.1 - 2.1e-72 244.0 0.0 4.1e-48 164.0 0.0 2.1 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 CBZ32956.1 - 1.2e-09 37.5 0.0 2.2e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 CBZ32956.1 - 0.00076 19.9 0.0 0.018 15.5 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA DUF1796 PF08795.10 CBZ32957.1 - 7e-51 172.5 0.0 1.3e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) DDRGK PF09756.9 CBZ32957.1 - 0.19 11.3 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 DDRGK domain Nop PF01798.18 CBZ32958.1 - 3.1e-81 272.2 0.5 4.3e-81 271.8 0.5 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CBZ32958.1 - 0.00014 22.2 0.5 0.18 12.2 0.1 2.9 1 1 1 2 2 2 2 NOP5NT (NUC127) domain RHH_6 PF16762.5 CBZ32958.1 - 0.25 12.0 3.5 11 6.7 0.4 3.2 2 1 1 3 3 3 0 Ribbon-helix-helix domain TMEM164 PF14808.6 CBZ32959.1 - 9.6e-10 38.2 3.4 1.6e-09 37.5 3.4 1.3 1 0 0 1 1 1 1 TMEM164 family Alkyl_sulf_dimr PF14863.6 CBZ32960.1 - 0.0078 16.7 0.1 0.014 15.9 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Dynamitin PF04912.14 CBZ32960.1 - 0.036 13.4 0.1 0.054 12.8 0.1 1.2 1 0 0 1 1 1 0 Dynamitin ABC_tran_CTD PF16326.5 CBZ32960.1 - 0.061 13.6 1.3 0.13 12.5 1.3 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain Whib PF02467.16 CBZ32960.1 - 0.13 12.8 0.8 0.6 10.7 0.1 2.3 2 0 0 2 2 2 0 Transcription factor WhiB zf-RING_2 PF13639.6 CBZ32961.1 - 8.6e-13 48.4 7.6 1.8e-12 47.4 7.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CBZ32961.1 - 3.3e-07 29.9 2.5 7e-07 28.9 2.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CBZ32961.1 - 9.5e-07 28.8 6.2 1.7e-06 27.9 6.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ32961.1 - 1e-06 28.5 7.0 1.9e-06 27.6 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ32961.1 - 9.9e-06 25.8 9.3 2.6e-05 24.4 9.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CBZ32961.1 - 2.1e-05 24.3 5.7 3.9e-05 23.4 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ32961.1 - 0.00018 21.3 6.1 0.00033 20.4 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ32961.1 - 0.0024 17.8 5.7 0.0044 16.9 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 CBZ32961.1 - 0.015 15.4 7.3 0.34 11.1 7.3 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CBZ32961.1 - 0.026 14.6 4.6 0.062 13.4 4.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CBZ32961.1 - 0.031 14.1 5.3 0.063 13.1 5.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBZ32961.1 - 0.068 12.8 4.9 0.14 11.8 4.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Imm_superinfect PF14373.6 CBZ32961.1 - 0.088 12.8 1.6 0.2 11.6 1.6 1.6 1 0 0 1 1 1 0 Superinfection immunity protein zinc_ribbon_16 PF17034.5 CBZ32961.1 - 0.24 11.6 1.6 0.45 10.7 1.6 1.4 1 0 0 1 1 1 0 Zinc-ribbon like family zf-RING_4 PF14570.6 CBZ32961.1 - 0.56 10.0 6.6 1.3 8.9 6.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF5337 PF17272.2 CBZ32961.1 - 0.58 10.0 6.9 0.086 12.7 0.6 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5337) zf-RING-like PF08746.11 CBZ32961.1 - 2 8.8 6.3 3.7 7.9 6.3 1.4 1 0 0 1 1 1 0 RING-like domain MutS_V PF00488.21 CBZ32962.1 - 2.9e-49 167.7 0.0 2.2e-48 164.8 0.0 2.1 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CBZ32962.1 - 6.5e-22 78.7 0.1 1e-21 78.0 0.1 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CBZ32962.1 - 1.3e-19 70.5 0.0 2.2e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 CBZ32962.1 - 0.027 14.8 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 MutS family domain IV tRNA-synt_1c PF00749.21 CBZ32964.1 - 1.4e-104 349.3 0.0 1.9e-104 348.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CBZ32964.1 - 3.9e-40 137.6 0.0 6.4e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain PCNA_N PF00705.18 CBZ32965.1 - 5.5e-42 142.5 1.3 9.6e-42 141.7 0.8 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CBZ32965.1 - 6.8e-38 129.7 0.1 1.8e-19 70.2 0.1 2.3 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CBZ32965.1 - 3.8e-07 29.8 0.0 4.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 CBZ32965.1 - 0.00037 19.6 0.1 0.0068 15.5 0.1 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 CBZ32965.1 - 0.022 13.9 0.0 0.33 10.0 0.0 2.1 2 0 0 2 2 2 0 Hus1-like protein Diphthami_syn_2 PF01902.17 CBZ32965.1 - 0.088 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Diphthamide synthase GHMP_kinases_N PF00288.26 CBZ32966.1 - 4.5e-14 52.4 1.3 1.4e-13 50.8 1.3 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CBZ32966.1 - 4.8e-07 30.1 0.1 2.4e-05 24.6 0.1 2.5 2 0 0 2 2 2 1 GHMP kinases C terminal Gpr1_Fun34_YaaH PF01184.19 CBZ32967.1 - 0.0039 16.8 0.1 0.0044 16.6 0.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ICE2 PF08426.10 CBZ32967.1 - 0.029 13.5 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 ICE2 Ribosomal_L7Ae PF01248.26 CBZ32968.1 - 4.2e-25 87.3 0.1 4.9e-25 87.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CBZ32968.1 - 3.2e-05 23.7 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CBZ32968.1 - 0.0014 18.7 0.2 0.0015 18.6 0.2 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PDEase_I PF00233.19 CBZ32969.1 - 2.3e-70 237.0 0.2 4.5e-70 236.1 0.0 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CBZ32969.1 - 1.3e-30 106.7 0.1 3.8e-15 56.7 0.0 3.3 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 CBZ32969.1 - 2.3e-18 66.9 0.1 7.5e-07 29.5 0.0 3.4 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 CBZ32969.1 - 5.6e-08 33.2 0.0 0.0024 18.2 0.0 2.9 2 1 0 2 2 2 2 GAF domain DUF58 PF01882.18 CBZ32969.1 - 0.095 13.0 1.7 3.4 8.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF58 PDEase_I PF00233.19 CBZ32970.1 - 2.3e-70 237.0 0.2 4.5e-70 236.1 0.0 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 CBZ32970.1 - 1.3e-30 106.7 0.1 3.8e-15 56.7 0.0 3.3 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 CBZ32970.1 - 2.3e-18 66.9 0.1 7.5e-07 29.5 0.0 3.4 3 0 0 3 3 3 3 GAF domain GAF_3 PF13492.6 CBZ32970.1 - 5.6e-08 33.2 0.0 0.0024 18.2 0.0 2.9 2 1 0 2 2 2 2 GAF domain DUF58 PF01882.18 CBZ32970.1 - 0.095 13.0 1.7 3.4 8.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function DUF58 HMG_box_2 PF09011.10 CBZ32971.1 - 0.075 13.6 0.1 0.16 12.6 0.1 1.5 1 0 0 1 1 1 0 HMG-box domain SMRP1 PF15181.6 CBZ32973.1 - 0.031 13.9 0.1 0.12 11.9 0.3 1.7 2 0 0 2 2 2 0 Spermatid-specific manchette-related protein 1 Sld5 PF05916.11 CBZ32973.1 - 0.049 14.1 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 GINS complex protein Presenilin PF01080.17 CBZ32975.1 - 2.1e-73 247.4 33.7 5.2e-51 173.7 20.2 2.0 1 1 1 2 2 2 2 Presenilin Wyosine_form PF08608.12 CBZ32976.1 - 1.5e-17 63.6 0.0 3.6e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CBZ32976.1 - 8.9e-17 62.0 0.0 1.8e-16 61.0 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Paf67 PF10255.9 CBZ32976.1 - 0.053 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 Pkinase PF00069.25 CBZ32978.1 - 4.6e-58 196.7 0.0 6.2e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ32978.1 - 2.3e-26 92.6 0.0 1.7e-25 89.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 CBZ32978.1 - 2.2e-15 56.5 5.6 4.4e-15 55.6 5.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.23 CBZ32978.1 - 4.9e-05 23.4 0.1 0.00096 19.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ32978.1 - 0.00059 18.7 0.0 0.00087 18.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FYVE_2 PF02318.16 CBZ32978.1 - 0.0016 18.6 4.5 0.0016 18.6 4.5 1.9 2 0 0 2 2 2 1 FYVE-type zinc finger DZR PF12773.7 CBZ32978.1 - 0.0041 17.1 3.3 0.1 12.7 0.2 2.7 2 0 0 2 2 2 1 Double zinc ribbon Siva PF05458.12 CBZ32978.1 - 0.056 13.1 5.0 0.15 11.7 5.0 1.7 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Choline_kinase PF01633.20 CBZ32978.1 - 0.064 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase NOB1_Zn_bind PF08772.11 CBZ32978.1 - 1.4 9.1 7.9 0.5 10.6 4.5 2.0 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Cnd1 PF12717.7 CBZ32979.1 - 1.7e-20 73.7 4.0 1e-17 64.6 0.1 3.9 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 CBZ32979.1 - 1.9e-05 24.0 0.7 0.018 14.2 0.1 2.9 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CBZ32979.1 - 2.2e-05 24.3 4.8 0.63 10.5 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 CBZ32979.1 - 0.00014 22.2 5.1 3 8.3 0.0 5.4 4 2 2 6 6 6 2 HEAT repeats Cnd1_N PF12922.7 CBZ32979.1 - 0.00036 20.4 0.0 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Nipped-B_C PF12830.7 CBZ32979.1 - 0.027 14.4 0.4 9.5 6.1 0.0 3.3 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.6 CBZ32979.1 - 0.1 13.1 0.3 29 5.3 0.0 4.0 3 0 0 3 3 3 0 HEAT-like repeat SR-25 PF10500.9 CBZ32980.1 - 0.1 12.2 7.6 0.16 11.6 7.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ASF1_hist_chap PF04729.13 CBZ32981.1 - 1e-24 87.3 0.0 1.2e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF5597 PF18120.1 CBZ32981.1 - 0.074 13.2 0.0 0.095 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5597) Ribosomal_L27A PF00828.19 CBZ32982.1 - 6.5e-07 30.1 0.0 1.1e-06 29.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ADK PF00406.22 CBZ32983.1 - 5.7e-11 42.7 0.5 0.00017 21.8 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CBZ32983.1 - 2.6e-09 37.6 0.1 6.8e-07 29.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ32983.1 - 1.2e-06 29.1 0.0 5e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ32983.1 - 4.7e-06 27.0 1.1 8.1e-06 26.2 0.2 1.8 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 CBZ32983.1 - 2.8e-05 23.9 0.1 4.6e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ32983.1 - 3.8e-05 24.1 0.1 7.5e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CBZ32983.1 - 5.1e-05 23.5 0.3 0.00012 22.3 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ32983.1 - 6.5e-05 23.2 0.1 0.00015 22.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBZ32983.1 - 0.00026 20.7 0.5 0.00042 20.1 0.5 1.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CBZ32983.1 - 0.00034 20.6 0.2 0.00061 19.7 0.2 1.4 1 0 0 1 1 1 1 NTPase SRP54 PF00448.22 CBZ32983.1 - 0.00042 20.0 0.1 0.00074 19.2 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA PF00004.29 CBZ32983.1 - 0.00049 20.5 0.3 0.00094 19.6 0.3 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ32983.1 - 0.00077 19.5 0.0 0.0029 17.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CBZ32983.1 - 0.0011 18.5 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CBZ32983.1 - 0.0013 18.7 0.1 0.0022 17.9 0.1 1.4 1 0 0 1 1 1 1 NACHT domain DUF5582 PF17819.1 CBZ32983.1 - 0.0027 18.2 0.1 0.01 16.3 0.0 1.9 3 0 0 3 3 1 1 Family of unknown function (DUF5582) AAA_24 PF13479.6 CBZ32983.1 - 0.0036 17.0 0.1 0.0061 16.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBZ32983.1 - 0.004 16.3 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CBZ32983.1 - 0.0046 17.3 0.5 0.0071 16.7 0.5 1.5 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 CBZ32983.1 - 0.005 16.5 0.1 0.0077 15.8 0.1 1.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Hydin_ADK PF17213.3 CBZ32983.1 - 0.0059 16.9 2.2 0.0059 16.9 2.2 1.9 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain Mg_chelatase PF01078.21 CBZ32983.1 - 0.0072 15.7 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CBZ32983.1 - 0.0084 16.1 0.1 0.023 14.7 0.0 1.7 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 CBZ32983.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 CBZ32983.1 - 0.015 14.6 0.0 0.055 12.8 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.10 CBZ32983.1 - 0.017 14.6 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.22 CBZ32983.1 - 0.025 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 CBZ32983.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBZ32983.1 - 0.026 14.2 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CBZ32983.1 - 0.029 14.8 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 CBZ32983.1 - 0.038 13.7 0.1 0.068 12.9 0.1 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 CBZ32983.1 - 0.043 13.7 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CBZ32983.1 - 0.043 13.0 0.1 0.063 12.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3987 PF13148.6 CBZ32983.1 - 0.054 12.5 0.0 0.089 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ATPase_2 PF01637.18 CBZ32983.1 - 0.059 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 CBZ32983.1 - 0.059 13.9 0.1 0.081 13.4 0.1 1.5 1 1 0 1 1 1 0 ABC transporter dNK PF01712.19 CBZ32983.1 - 0.065 13.1 0.0 0.086 12.7 0.0 1.5 1 1 0 1 1 1 0 Deoxynucleoside kinase ResIII PF04851.15 CBZ32983.1 - 0.068 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CBZ32983.1 - 0.086 12.6 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CBZ32983.1 - 0.087 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CBZ32983.1 - 0.09 12.2 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Cytidylate_kin PF02224.18 CBZ32983.1 - 0.094 12.4 0.3 0.17 11.6 0.3 1.4 1 0 0 1 1 1 0 Cytidylate kinase DnaB_C PF03796.15 CBZ32983.1 - 0.095 12.0 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain CobU PF02283.16 CBZ32983.1 - 0.097 12.2 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase ATPase PF06745.13 CBZ32983.1 - 0.11 11.8 0.1 0.17 11.2 0.1 1.4 1 1 0 1 1 1 0 KaiC ATP_bind_1 PF03029.17 CBZ32983.1 - 0.11 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 CBZ32983.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Rad17 PF03215.15 CBZ32983.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain GTP_EFTU PF00009.27 CBZ32983.1 - 0.12 12.0 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain PRK PF00485.18 CBZ32983.1 - 0.13 12.0 0.3 0.24 11.1 0.0 1.5 2 0 0 2 2 1 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.20 CBZ32983.1 - 0.13 12.1 0.2 0.28 11.0 0.1 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_23 PF13476.6 CBZ32983.1 - 0.18 12.3 0.1 0.34 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CBZ32983.1 - 0.21 11.7 0.4 0.32 11.1 0.4 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PrmA PF06325.13 CBZ32984.1 - 0.00014 21.3 0.4 0.00021 20.8 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CBZ32984.1 - 0.0058 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CBZ32984.1 - 0.031 15.0 0.1 0.072 13.8 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain AcetDehyd-dimer PF09290.11 CBZ32984.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation CMAS PF02353.20 CBZ32984.1 - 0.12 11.6 0.2 0.31 10.3 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CBZ32984.1 - 0.14 12.8 0.0 0.3 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_3 PF13640.6 CBZ32985.1 - 3.7e-11 43.8 0.0 1.6e-10 41.7 0.1 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 CBZ32985.1 - 9.6e-05 22.7 0.0 0.00017 21.9 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy PF03171.20 CBZ32985.1 - 0.039 14.4 0.0 0.088 13.3 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 CBZ32986.1 - 1.3e-15 57.6 0.0 1.9e-13 50.6 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ32986.1 - 1.5e-13 51.1 0.0 6e-13 49.1 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ32986.1 - 0.079 13.0 0.0 0.28 11.2 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ32986.1 - 0.11 12.7 0.2 31 4.8 0.1 3.0 3 1 0 3 3 3 0 AAA domain DUF4217 PF13959.6 CBZ32986.1 - 0.13 12.5 0.3 2.4 8.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) AAA PF00004.29 CBZ32987.1 - 2.7e-45 154.0 0.0 5.9e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBZ32987.1 - 1.9e-06 27.7 0.0 3.8e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 CBZ32987.1 - 5.1e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 CBZ32987.1 - 0.00015 22.2 1.0 0.0051 17.2 0.0 3.1 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 CBZ32987.1 - 0.00018 21.7 0.0 0.00039 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CBZ32987.1 - 0.002 18.3 0.0 0.0072 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 CBZ32987.1 - 0.0033 16.6 0.0 0.0057 15.8 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 CBZ32987.1 - 0.0038 17.2 0.0 0.016 15.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBZ32987.1 - 0.0047 17.3 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CBZ32987.1 - 0.0047 17.0 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ32987.1 - 0.0069 16.7 0.0 0.13 12.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 CBZ32987.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 CBZ32987.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CBZ32987.1 - 0.018 15.6 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 CBZ32987.1 - 0.018 14.4 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CBZ32987.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 CBZ32987.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_lid_3 PF17862.1 CBZ32987.1 - 0.035 13.9 2.5 0.068 13.0 0.0 2.8 3 0 0 3 3 3 0 AAA+ lid domain AAA_28 PF13521.6 CBZ32987.1 - 0.053 13.8 0.0 0.27 11.5 0.0 2.3 3 0 0 3 3 1 0 AAA domain ATPase PF06745.13 CBZ32987.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 CBZ32987.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 CBZ32987.1 - 0.12 12.9 0.0 0.39 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBZ32987.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain INT_SG_DDX_CT_C PF15300.6 CBZ32988.1 - 0.19 11.6 0.1 0.47 10.3 0.0 1.7 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Kelch_4 PF13418.6 CBZ32989.1 - 7.6e-34 115.5 0.2 2.4e-09 37.0 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ32989.1 - 9.1e-29 99.0 1.4 0.00061 19.7 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CBZ32989.1 - 1e-24 85.9 4.7 4.8e-05 23.5 0.0 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CBZ32989.1 - 5.6e-22 77.5 5.6 0.0044 17.3 0.0 7.0 7 1 0 7 7 7 6 Galactose oxidase, central domain DUF4110 PF13422.6 CBZ32989.1 - 1.7e-19 69.6 10.3 1.7e-19 69.6 10.3 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 CBZ32989.1 - 6e-19 67.4 0.1 2.7e-05 23.6 0.0 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CBZ32989.1 - 1.5e-15 56.4 2.4 0.0038 17.1 0.0 6.4 6 0 0 6 6 6 4 Kelch motif MORN PF02493.20 CBZ32991.1 - 7e-13 47.6 7.8 3.7e-08 32.8 0.8 4.2 4 0 0 4 4 4 2 MORN repeat Vma12 PF11712.8 CBZ32991.1 - 0.089 12.9 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Peptidase_U4 PF03419.13 CBZ32991.1 - 1.7 7.8 5.1 0.5 9.6 0.7 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA APH PF01636.23 CBZ32992.1 - 8.6e-13 48.8 0.0 2.7e-12 47.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-RAG1 PF10426.9 CBZ32994.1 - 0.31 11.2 2.2 0.7 10.1 2.2 1.6 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain eIF-1a PF01176.19 CBZ32995.1 - 1.4e-12 47.2 0.3 2.1e-12 46.6 0.3 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ribosomal_L17 PF01196.19 CBZ32997.1 - 9.6e-13 48.8 0.1 1.4e-12 48.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 Las1 PF04031.13 CBZ33000.1 - 4e-32 111.5 0.1 6.2e-32 110.8 0.1 1.3 1 0 0 1 1 1 1 Las1-like DUF5337 PF17272.2 CBZ33000.1 - 0.019 14.8 0.3 0.04 13.8 0.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Mito_carr PF00153.27 CBZ33001.1 - 1.6e-62 207.5 0.5 2.7e-20 72.1 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CBZ33002.1 - 4.9e-54 180.3 3.0 4.7e-18 64.9 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein MAP65_ASE1 PF03999.12 CBZ33002.1 - 0.0043 15.8 0.0 0.0058 15.4 0.0 1.1 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DSPc PF00782.20 CBZ33004.1 - 5.3e-08 32.8 0.0 7.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ33004.1 - 0.00013 21.6 0.0 0.00016 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Radical_SAM_C PF16199.5 CBZ33005.1 - 2.8e-21 75.3 0.1 6.5e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CBZ33005.1 - 7.8e-15 55.6 0.0 2.3e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CBZ33005.1 - 5.5e-07 29.8 0.1 1.4e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBZ33005.1 - 7.6e-05 22.6 0.1 0.00015 21.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DSPc PF00782.20 CBZ33006.1 - 1.1e-07 31.7 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ33006.1 - 0.00014 21.5 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Hydrolase_4 PF12146.8 CBZ33007.1 - 9.3e-13 48.0 0.8 1.1e-06 28.0 0.5 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ33007.1 - 2.1e-09 37.4 0.1 8.5e-06 25.6 0.1 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBZ33007.1 - 3.1e-08 34.5 0.0 6.9e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ank_2 PF12796.7 CBZ33007.1 - 1.4e-07 32.0 0.0 6.8e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ33007.1 - 3.9e-07 30.5 0.5 0.00076 20.0 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Peptidase_S9 PF00326.21 CBZ33007.1 - 2.6e-06 27.0 0.1 0.026 14.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ank_5 PF13857.6 CBZ33007.1 - 1.6e-05 25.1 0.4 5.8e-05 23.3 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ33007.1 - 1.7e-05 24.8 0.5 0.00021 21.5 0.0 2.8 3 0 0 3 3 2 1 Ankyrin repeat AXE1 PF05448.12 CBZ33007.1 - 4.6e-05 22.3 1.1 0.0069 15.1 1.1 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Ank PF00023.30 CBZ33007.1 - 5.4e-05 23.4 0.1 0.00028 21.2 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat Peptidase_S15 PF02129.18 CBZ33007.1 - 0.0027 17.3 0.0 0.058 13.0 0.1 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) RIH_assoc PF08454.11 CBZ33009.1 - 7.6e-20 70.7 1.8 2.2e-19 69.2 0.9 2.3 2 0 0 2 2 2 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 CBZ33009.1 - 2.7e-14 52.9 0.0 4.2e-13 49.0 0.0 2.7 2 1 1 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Ion_trans PF00520.31 CBZ33009.1 - 1.8e-07 30.7 9.9 4.2e-07 29.4 9.9 1.6 1 0 0 1 1 1 1 Ion transport protein MIR PF02815.19 CBZ33009.1 - 2.3e-06 27.6 0.0 0.087 12.7 0.0 2.4 2 0 0 2 2 2 2 MIR domain RYDR_ITPR PF01365.21 CBZ33009.1 - 0.00027 20.4 0.0 0.00084 18.8 0.0 1.8 1 0 0 1 1 1 1 RIH domain Nas2_N PF18265.1 CBZ33010.1 - 1e-21 76.6 0.0 1.8e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 CBZ33010.1 - 0.00041 20.1 0.1 0.0017 18.2 0.0 2.1 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 CBZ33010.1 - 0.0042 17.4 0.0 0.0068 16.7 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 CBZ33010.1 - 0.0073 16.6 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF4407 PF14362.6 CBZ33010.1 - 0.16 11.3 6.9 0.22 10.9 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COMMD1_N PF17221.3 CBZ33010.1 - 0.16 12.3 4.7 0.052 13.8 1.7 1.6 2 0 0 2 2 2 0 COMMD1 N-terminal domain PSK_trans_fac PF07704.11 CBZ33010.1 - 1.6 9.6 13.3 2.9 8.7 0.3 3.0 3 0 0 3 3 3 0 Rv0623-like transcription factor KfrA_N PF11740.8 CBZ33010.1 - 3 8.6 16.6 9.4 7.0 0.7 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term HAUS-augmin3 PF14932.6 CBZ33010.1 - 4.3 6.8 12.6 12 5.3 0.3 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Pkinase PF00069.25 CBZ33011.1 - 1.2e-67 228.1 0.0 1.6e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33011.1 - 1.6e-49 168.6 0.0 2.1e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ33011.1 - 4e-05 22.6 0.0 6e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ33011.1 - 0.017 14.4 0.1 0.079 12.3 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Met_10 PF02475.16 CBZ33012.1 - 2.5e-47 161.2 0.0 2.6e-35 122.0 0.0 2.2 2 0 0 2 2 2 2 Met-10+ like-protein PrmA PF06325.13 CBZ33012.1 - 0.007 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 CBZ33012.1 - 0.1 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Glyco_transf_64 PF09258.10 CBZ33012.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain FHA PF00498.26 CBZ33013.1 - 5.1e-14 52.4 0.0 9.6e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain EBP PF05241.12 CBZ33015.1 - 2.2e-19 69.6 0.7 2.6e-19 69.4 0.7 1.1 1 0 0 1 1 1 1 Emopamil binding protein 2OG-FeII_Oxy_2 PF13532.6 CBZ33016.1 - 2.9e-56 190.8 0.1 3.9e-56 190.3 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SpvB PF03534.13 CBZ33016.1 - 0.0069 15.6 0.1 2.4 7.3 0.0 2.1 2 0 0 2 2 2 2 Salmonella virulence plasmid 65kDa B protein 4HBT PF03061.22 CBZ33017.1 - 0.04 14.3 1.8 0.21 12.0 1.1 2.4 2 0 0 2 2 2 0 Thioesterase superfamily DUF4763 PF15960.5 CBZ33018.1 - 0.029 13.7 0.4 0.048 13.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Beta_helix PF13229.6 CBZ33018.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Right handed beta helix region TolA_bind_tri PF16331.5 CBZ33018.1 - 0.16 12.1 1.6 0.28 11.3 1.6 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation Lectin_N PF03954.14 CBZ33018.1 - 0.2 11.4 2.0 0.36 10.6 2.0 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Tektin PF03148.14 CBZ33018.1 - 0.26 10.0 1.4 0.38 9.5 1.4 1.1 1 0 0 1 1 1 0 Tektin family DUF3138 PF11336.8 CBZ33018.1 - 8.3 4.9 14.5 0.21 10.2 6.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) TTL PF03133.15 CBZ33019.1 - 6.2e-78 261.9 0.0 5.9e-56 189.8 0.0 2.3 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 CBZ33019.1 - 9.1e-06 25.1 0.0 0.032 13.5 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 CBZ33019.1 - 3.8e-05 23.1 0.0 0.11 11.7 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 CBZ33019.1 - 0.1 12.7 0.0 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain XRN_N PF03159.18 CBZ33020.1 - 1.5e-19 70.4 4.6 1.6e-17 63.8 0.0 3.7 3 1 0 3 3 3 2 XRN 5'-3' exonuclease N-terminus Macoilin PF09726.9 CBZ33022.1 - 0.023 13.3 0.8 0.029 12.9 0.8 1.3 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 CBZ33022.1 - 0.49 9.0 4.7 0.71 8.5 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein Pyridoxal_deC PF00282.19 CBZ33023.1 - 7.6e-19 67.7 0.1 5.7e-13 48.3 0.0 2.5 2 1 1 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain Fucokinase PF07959.12 CBZ33025.1 - 2.3e-15 56.5 0.0 2.1e-13 50.0 0.0 2.5 1 1 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.26 CBZ33025.1 - 8.2e-06 26.0 0.0 4.2e-05 23.7 0.0 2.4 1 1 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CBZ33025.1 - 0.0025 18.1 0.2 0.0087 16.4 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal Sensor PF13796.6 CBZ33027.1 - 0.0014 18.7 0.0 0.099 12.7 0.0 2.2 1 1 1 2 2 2 1 Putative sensor Tetraspanin PF00335.20 CBZ33027.1 - 4.6 6.9 22.7 0.13 12.0 15.0 2.1 1 1 1 2 2 2 0 Tetraspanin family TMEM192 PF14802.6 CBZ33027.1 - 9.3 5.3 7.2 15 4.5 6.4 1.7 1 1 0 1 1 1 0 TMEM192 family Amastin PF07344.11 CBZ33030.1 - 0.00035 20.5 16.8 0.00035 20.5 16.8 1.7 1 1 0 1 1 1 1 Amastin surface glycoprotein EphA2_TM PF14575.6 CBZ33030.1 - 0.044 14.7 7.5 1.1 10.2 0.0 3.8 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DHO_dh PF01180.21 CBZ33033.1 - 1.9e-67 227.6 0.0 2.1e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CBZ33033.1 - 0.039 13.0 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase F_bP_aldolase PF01116.20 CBZ33033.1 - 0.074 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II PcrB PF01884.17 CBZ33033.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 PcrB family OTCace_N PF02729.21 CBZ33034.1 - 5.1e-41 140.1 0.6 8.1e-41 139.5 0.6 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 CBZ33034.1 - 5.3e-31 107.8 0.0 2e-29 102.7 0.0 2.0 2 0 0 2 2 2 2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OMPdecase PF00215.24 CBZ33035.1 - 2.6e-36 125.3 0.0 3.9e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 CBZ33035.1 - 3e-18 65.8 1.1 5.2e-18 65.1 0.2 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBZ33035.1 - 0.00068 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CBZ33035.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase AAA_18 PF13238.6 CBZ33036.1 - 0.00092 19.8 0.0 0.0026 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 CBZ33036.1 - 0.019 14.7 0.0 0.063 13.0 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 CBZ33036.1 - 0.038 14.1 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CBZ33036.1 - 0.05 13.3 0.1 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase CPT PF07931.12 CBZ33036.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Amidohydro_1 PF01979.20 CBZ33037.1 - 4.7e-09 36.0 0.4 6.8e-09 35.5 0.4 1.2 1 0 0 1 1 1 1 Amidohydrolase family TatD_DNase PF01026.21 CBZ33037.1 - 0.0097 15.3 1.6 0.019 14.3 0.3 1.9 1 1 1 2 2 2 1 TatD related DNase Amidohydro_2 PF04909.14 CBZ33037.1 - 0.022 14.6 0.7 1.5 8.5 0.6 2.6 2 1 0 2 2 2 0 Amidohydrolase CPSase_L_D2 PF02786.17 CBZ33038.1 - 1.2e-102 341.8 0.5 2.2e-77 259.3 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CBZ33038.1 - 4.8e-45 152.5 0.0 1.3e-44 151.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CBZ33038.1 - 7e-42 143.3 0.0 1.7e-41 142.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CBZ33038.1 - 2.5e-31 108.6 0.0 6.1e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CBZ33038.1 - 2.9e-22 79.0 0.3 3.6e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Arginosuc_synth PF00764.19 CBZ33038.1 - 4.7e-14 52.5 0.1 3.2e-13 49.8 0.0 2.2 3 0 0 3 3 3 1 Arginosuccinate synthase Dala_Dala_lig_C PF07478.13 CBZ33038.1 - 3.6e-13 49.5 1.0 2.6e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CBZ33038.1 - 8.7e-11 41.7 0.0 1.3e-05 24.9 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 CBZ33038.1 - 1.3e-07 31.6 0.5 8.2e-06 25.7 0.5 2.5 1 1 0 1 1 1 1 Peptidase C26 MGS PF02142.22 CBZ33038.1 - 2.5e-07 30.8 0.0 1.2e-06 28.6 0.0 2.3 2 0 0 2 2 1 1 MGS-like domain ATP-grasp_3 PF02655.14 CBZ33038.1 - 1.5e-05 25.1 0.4 0.00089 19.3 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 CBZ33038.1 - 2.9e-05 23.9 0.5 0.14 11.9 0.0 3.3 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.24 CBZ33038.1 - 0.0022 17.8 0.1 0.023 14.5 0.0 2.7 3 0 0 3 3 3 1 DJ-1/PfpI family TrkA_N PF02254.18 CBZ33038.1 - 0.0056 16.9 0.0 0.05 13.9 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain GSH-S_ATP PF02955.16 CBZ33038.1 - 0.0065 15.9 0.0 0.021 14.2 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain GSP_synth PF03738.14 CBZ33038.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Glutathionylspermidine synthase preATP-grasp Histone PF00125.24 CBZ33040.1 - 7.2e-31 107.3 2.6 8e-31 107.1 2.6 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Mitochondr_Som1 PF11093.8 CBZ33040.1 - 0.067 13.2 0.2 0.085 12.9 0.2 1.4 1 1 0 1 1 1 0 Mitochondrial export protein Som1 Pam16 PF03656.13 CBZ33041.1 - 0.18 11.8 1.9 0.75 9.8 1.9 2.1 1 0 0 1 1 1 0 Pam16 CCDC-167 PF15188.6 CBZ33042.1 - 0.18 12.2 0.2 0.37 11.2 0.2 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Chorion_2 PF03964.15 CBZ33042.1 - 2.6 9.0 9.0 0.42 11.5 2.1 2.3 2 0 0 2 2 2 0 Chorion family 2 RRM_1 PF00076.22 CBZ33043.1 - 1.4e-13 50.5 0.0 2.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.21 CBZ33043.1 - 3e-07 30.8 0.0 0.014 15.7 0.0 2.3 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-rbx1 PF12678.7 CBZ33044.1 - 4.4e-17 62.1 12.3 6.1e-17 61.7 12.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ33044.1 - 5.1e-14 52.1 7.0 6.4e-14 51.8 7.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBZ33044.1 - 2.6e-09 37.3 15.1 3.3e-07 30.5 15.5 2.2 1 1 1 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ33044.1 - 4.5e-07 29.6 11.4 1e-05 25.3 8.4 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBZ33044.1 - 5.2e-06 26.3 12.8 2e-05 24.4 8.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBZ33044.1 - 2.3e-05 24.3 11.9 0.00071 19.6 11.8 2.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.6 CBZ33044.1 - 8.2e-05 22.4 4.5 8.2e-05 22.4 4.5 1.7 1 1 1 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 CBZ33044.1 - 0.00032 20.5 13.2 0.0024 17.7 7.9 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ33044.1 - 0.00053 19.8 12.4 0.0028 17.5 12.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ33044.1 - 0.00058 19.7 17.6 0.1 12.5 17.6 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 CBZ33044.1 - 0.0062 15.9 0.2 0.0062 15.9 0.2 1.6 1 1 1 2 2 2 1 Rtf2 RING-finger FANCL_C PF11793.8 CBZ33044.1 - 0.0099 16.0 13.6 0.03 14.5 3.6 3.1 1 1 1 3 3 3 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CBZ33044.1 - 0.02 14.5 13.7 0.064 12.9 13.7 2.0 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Di19 PF05605.12 CBZ33044.1 - 0.076 13.3 8.5 0.19 12.1 3.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.6 CBZ33044.1 - 0.11 12.4 9.3 2.2 8.1 6.4 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 CBZ33044.1 - 0.11 13.0 8.5 1.6 9.3 0.0 3.4 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain TerY_C PF15616.6 CBZ33044.1 - 0.39 10.8 9.9 0.79 9.8 6.1 2.0 1 1 1 2 2 2 0 TerY-C metal binding domain tRNA-synt_1g PF09334.11 CBZ33044.1 - 0.44 9.2 3.2 1.7 7.3 0.5 2.0 1 1 1 2 2 2 0 tRNA synthetases class I (M) zf-RING_11 PF17123.5 CBZ33044.1 - 0.68 9.7 14.1 16 5.3 14.1 2.5 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 CBZ33044.1 - 0.71 10.1 13.4 26 5.1 1.8 3.5 1 1 2 3 3 3 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 CBZ33044.1 - 0.88 9.7 10.0 0.91 9.7 5.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) zf-Nse PF11789.8 CBZ33044.1 - 0.93 9.4 7.4 5.1 7.0 7.4 2.1 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit HMMR_N PF15905.5 CBZ33045.1 - 0.00099 18.7 26.4 0.00099 18.7 26.4 4.4 2 2 2 4 4 4 2 Hyaluronan mediated motility receptor N-terminal DUF4061 PF13270.6 CBZ33045.1 - 0.019 15.2 1.4 0.019 15.2 1.4 7.2 2 2 5 7 7 7 0 Domain of unknown function (DUF4061) KELK PF15796.5 CBZ33045.1 - 0.026 14.9 3.8 0.026 14.9 3.8 7.6 4 3 3 7 7 7 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1738 PF08401.11 CBZ33046.1 - 9.8e-05 22.5 0.0 0.035 14.2 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1738) Exo_endo_phos PF03372.23 CBZ33047.1 - 1.3e-15 57.6 0.4 4.6e-15 55.8 0.4 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribos_L4_asso_C PF14374.6 CBZ33047.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 60S ribosomal protein L4 C-terminal domain eIF2A PF08662.11 CBZ33048.1 - 8.4e-38 130.2 0.0 1.6e-33 116.3 0.0 3.2 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A LysM PF01476.20 CBZ33049.1 - 1.7e-08 34.4 0.0 0.00058 19.9 0.0 2.4 2 0 0 2 2 2 2 LysM domain LRR_6 PF13516.6 CBZ33051.1 - 3e-09 36.2 20.1 0.7 10.1 0.1 6.5 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 CBZ33051.1 - 8.1e-07 29.3 10.7 0.0017 18.7 0.3 4.8 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ33051.1 - 0.00078 19.2 10.5 0.67 9.8 2.5 4.8 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 CBZ33051.1 - 0.0013 19.0 12.4 8.8 7.3 0.0 5.7 6 0 0 6 6 6 3 Leucine Rich Repeat UCH PF00443.29 CBZ33052.1 - 8.7e-36 123.7 0.0 1.5e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ33052.1 - 9.8e-17 61.5 0.1 1.6e-15 57.5 0.0 2.4 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-RanBP PF00641.18 CBZ33052.1 - 0.0067 15.7 0.9 0.0067 15.7 0.9 2.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Prok-RING_1 PF14446.6 CBZ33052.1 - 0.091 12.7 1.4 0.51 10.3 1.4 2.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 HAD PF12710.7 CBZ33054.1 - 0.12 12.7 0.6 1.3 9.4 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TAL_FSA PF00923.19 CBZ33055.1 - 4.8e-97 324.8 0.1 5.4e-97 324.6 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase SH3BGR PF04908.15 CBZ33056.1 - 0.00054 20.1 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein VPS13 PF16908.5 CBZ33057.1 - 1.1e-28 100.7 0.0 3.3e-28 99.1 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CBZ33057.1 - 2.1e-21 76.5 0.2 7.3e-15 55.2 0.0 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CBZ33057.1 - 5.2e-17 62.0 1.6 1.2e-10 41.5 0.1 2.9 2 1 0 2 2 2 2 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 CBZ33057.1 - 6.2e-13 48.7 0.0 6.5e-12 45.4 0.0 2.5 3 0 0 3 3 3 1 Repeating coiled region of VPS13 SHR-BD PF06650.12 CBZ33057.1 - 1.6e-07 31.0 0.1 0.63 9.4 0.0 4.3 3 1 0 3 3 3 3 SHR-binding domain of vacuolar-sorting associated protein 13 Glyco_hydro_18 PF00704.28 CBZ33058.1 - 1.1e-55 189.5 0.0 1.4e-55 189.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Mem_trans PF03547.18 CBZ33059.1 - 5.1e-12 44.9 18.4 2e-09 36.4 0.1 3.4 3 0 0 3 3 3 3 Membrane transport protein BILBO1_N PF18281.1 CBZ33061.1 - 2e-05 24.9 0.0 0.0066 16.8 0.0 2.6 2 0 0 2 2 2 2 BILBO1 N-terminal domain EF-hand_1 PF00036.32 CBZ33061.1 - 0.002 17.6 0.0 0.0044 16.5 0.0 1.5 1 0 0 1 1 1 1 EF hand Fe-S_biosyn PF01521.20 CBZ33062.1 - 6.1e-08 32.8 0.0 2.9e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Shugoshin_C PF07557.11 CBZ33062.1 - 0.021 14.6 0.2 0.057 13.2 0.2 1.8 1 0 0 1 1 1 0 Shugoshin C terminus JAB PF01398.21 CBZ33064.1 - 3.6e-20 72.1 0.0 5.6e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CBZ33064.1 - 0.0042 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.25 CBZ33066.1 - 7.4e-32 110.7 0.0 1.4e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33066.1 - 1.1e-23 83.8 0.0 1.9e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ33066.1 - 3e-05 23.0 0.0 5.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase zf-ACC PF17848.1 CBZ33066.1 - 0.12 12.4 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2_4 PF13894.6 CBZ33066.1 - 0.24 12.3 1.6 0.92 10.5 1.6 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger Nop52 PF05997.12 CBZ33068.1 - 2.8e-31 109.0 7.8 2.6e-27 96.0 0.4 3.8 4 0 0 4 4 4 3 Nucleolar protein,Nop52 EF-hand_6 PF13405.6 CBZ33072.1 - 1.4e-11 43.3 0.1 0.0033 17.2 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CBZ33072.1 - 1.1e-09 37.2 1.2 0.00046 19.5 0.0 3.3 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 CBZ33072.1 - 1.6e-07 31.7 0.4 2.6e-05 24.6 0.1 3.2 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 CBZ33072.1 - 1.3e-05 24.9 0.8 0.0057 16.5 0.0 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ33072.1 - 0.0074 15.7 1.0 0.11 12.0 0.1 2.9 3 1 0 3 3 3 1 EF hand FAM193_C PF15914.5 CBZ33072.1 - 0.1 12.4 0.3 0.21 11.3 0.3 1.5 1 0 0 1 1 1 0 FAM193 family C-terminal Snf7 PF03357.21 CBZ33073.1 - 1.5e-22 80.0 14.5 2e-22 79.6 14.5 1.2 1 0 0 1 1 1 1 Snf7 EPSP_synthase PF00275.20 CBZ33073.1 - 0.017 13.8 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) HeLo PF14479.6 CBZ33073.1 - 2.4 8.0 7.8 0.49 10.2 3.9 1.7 1 1 1 2 2 2 0 Prion-inhibition and propagation DUF3801 PF12687.7 CBZ33073.1 - 3.4 7.7 11.2 0.37 10.9 6.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3801) V_ATPase_I PF01496.19 CBZ33073.1 - 4 5.2 6.0 3.1 5.6 5.1 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Dynein_light PF01221.18 CBZ33074.1 - 4.4e-25 87.8 0.6 5.1e-25 87.6 0.6 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 YsaB PF13983.6 CBZ33074.1 - 0.11 12.7 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 YsaB-like lipoprotein DUF4854 PF16146.5 CBZ33074.1 - 0.16 12.3 1.6 0.19 12.1 0.7 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4854) Glycos_transf_1 PF00534.20 CBZ33075.1 - 9.2e-30 103.4 0.0 1.5e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ33075.1 - 1e-19 71.3 0.0 2e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBZ33075.1 - 0.00033 21.0 0.0 0.00089 19.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBZ33075.1 - 0.00079 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Methyltransf_23 PF13489.6 CBZ33076.1 - 5.5e-16 58.8 0.0 1.5e-14 54.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ33076.1 - 4.2e-14 53.0 0.0 6.7e-13 49.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ33076.1 - 7.4e-12 45.1 0.0 1.4e-10 40.9 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CBZ33076.1 - 3.4e-10 40.5 0.0 2.2e-07 31.5 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ33076.1 - 1.1e-06 28.5 0.0 4e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ33076.1 - 1.5e-06 28.9 0.0 0.00076 20.2 0.0 2.8 2 0 0 2 2 2 2 Methyltransferase domain DHR10 PF18595.1 CBZ33078.1 - 0.0011 19.0 4.7 0.0011 19.0 4.7 12.7 1 1 10 13 13 13 1 Designed helical repeat protein 10 domain DUF812 PF05667.11 CBZ33078.1 - 0.0016 17.4 39.1 0.0016 17.4 39.1 6.0 1 1 4 5 5 5 2 Protein of unknown function (DUF812) ApoLp-III PF07464.11 CBZ33078.1 - 0.0022 18.1 15.7 0.0022 18.1 15.7 7.4 2 1 5 8 8 8 1 Apolipophorin-III precursor (apoLp-III) UPF0242 PF06785.11 CBZ33078.1 - 0.0078 16.3 5.2 0.0078 16.3 5.2 8.4 1 1 7 8 8 8 3 Uncharacterised protein family (UPF0242) N-terminus DUF4041 PF13250.6 CBZ33078.1 - 0.17 11.8 1.4 2.5 8.0 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) Pkinase PF00069.25 CBZ33079.1 - 7.2e-58 196.0 0.0 9.7e-34 116.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33079.1 - 5.5e-28 97.9 0.0 4.7e-19 68.7 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase PNP_UDP_1 PF01048.20 CBZ33079.1 - 0.024 13.9 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphorylase superfamily Kdo PF06293.14 CBZ33079.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_Orf51 PF06194.11 CBZ33080.1 - 0.06 13.4 0.0 8.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 Phage_Orf51 PF06194.11 CBZ33081.1 - 0.06 13.4 0.0 8.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 Stealth_CR2 PF11380.8 CBZ33082.1 - 1e-08 35.3 0.0 7.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 CBZ33082.1 - 0.16 11.7 0.1 7.2 6.4 0.0 2.4 2 0 0 2 2 2 0 Stealth protein CR1, conserved region 1 Stealth_CR2 PF11380.8 CBZ33085.2 - 3e-15 56.3 0.0 2.6e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 CBZ33085.2 - 2.2 8.1 4.2 17 5.2 0.0 2.9 3 0 0 3 3 3 0 Stealth protein CR1, conserved region 1 Rib_recp_KP_reg PF05104.12 CBZ33086.1 - 0.084 13.9 3.9 0.12 13.4 3.9 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Phage_Orf51 PF06194.11 CBZ33086.1 - 0.11 12.5 0.0 15 5.7 0.0 2.3 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 Stealth_CR2 PF11380.8 CBZ33088.1 - 1e-12 48.2 0.0 6.5e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR2 PF11380.8 CBZ33089.1 - 1.9e-17 63.4 0.0 5.5e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 Stealth_CR3 PF17102.5 CBZ33089.1 - 3.2e-11 42.9 1.7 8e-11 41.7 1.7 1.7 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Ufm1 PF03671.14 CBZ33090.1 - 7.2e-35 118.9 0.1 8.7e-35 118.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein DUF4553 PF15090.6 CBZ33092.1 - 8 5.3 17.3 0.28 10.1 5.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4553) CALM_bind PF16025.5 CBZ33094.1 - 0.041 14.3 0.2 0.041 14.3 0.2 5.1 3 2 0 3 3 3 0 Calcium-dependent calmodulin binding Polyketide_cyc PF03364.20 CBZ33094.1 - 0.098 12.9 4.0 0.058 13.6 1.4 2.0 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 CBZ33095.1 - 2.7e-12 47.0 0.8 2.1e-11 44.2 0.8 2.1 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Antimicrobial_8 PF08103.11 CBZ33095.1 - 0.073 13.2 1.0 0.81 9.9 0.1 2.5 2 0 0 2 2 2 0 Uperin family DUF3292 PF11696.8 CBZ33095.1 - 0.55 8.5 1.7 0.86 7.9 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) tRNA_bind PF01588.20 CBZ33097.1 - 1e-22 80.0 0.0 1.7e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain WW PF00397.26 CBZ33098.1 - 1.6e-51 172.0 33.5 5e-14 52.1 1.3 5.3 5 0 0 5 5 5 5 WW domain Mcp5_PH PF12814.7 CBZ33098.1 - 3.8 7.6 4.4 19 5.4 0.2 3.3 4 0 0 4 4 4 0 Meiotic cell cortex C-terminal pleckstrin homology Tfb5 PF06331.12 CBZ33099.1 - 0.00025 21.0 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIIH complex subunit Tfb5 Ribosomal_L39 PF00832.20 CBZ33102.1 - 3.4e-18 65.0 15.4 3.8e-18 64.8 15.4 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Adap_comp_sub PF00928.21 CBZ33103.1 - 2.3e-13 50.1 0.0 4.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBZ33103.1 - 0.00013 21.9 0.1 0.00023 21.1 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AAA_25 PF13481.6 CBZ33103.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RSN1_7TM PF02714.15 CBZ33104.1 - 7.7e-24 84.4 8.6 1.4e-23 83.6 8.6 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate DUF4590 PF15257.6 CBZ33104.1 - 0.18 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) Pro_isomerase PF00160.21 CBZ33105.1 - 1.4e-31 109.9 0.0 2.1e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD dsrm PF00035.26 CBZ33106.1 - 3.6e-06 27.6 0.1 0.25 12.1 0.0 4.4 4 0 0 4 4 4 2 Double-stranded RNA binding motif Cullin PF00888.22 CBZ33107.1 - 6.5e-38 130.8 0.0 1.7e-31 109.6 0.0 3.7 4 1 0 4 4 4 2 Cullin family Cullin_Nedd8 PF10557.9 CBZ33107.1 - 1.9e-15 56.6 0.0 3.2e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Cullin protein neddylation domain LSM PF01423.22 CBZ33110.1 - 7.3e-05 22.4 0.1 0.00034 20.2 0.1 2.0 1 1 0 1 1 1 1 LSM domain CIA30 PF08547.12 CBZ33113.1 - 0.1 12.6 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) DAGK_acc PF00609.19 CBZ33114.1 - 7.3e-21 75.2 0.0 6.8e-20 72.0 0.0 2.2 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CBZ33114.1 - 7.3e-07 28.9 0.0 2.5e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Cytochrom_C PF00034.21 CBZ33116.1 - 2.1e-10 41.6 0.0 3.4e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CBZ33116.1 - 0.00018 21.8 0.9 0.0012 19.2 0.9 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CBZ33117.1 - 3.7e-11 44.0 0.0 4.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CBZ33117.1 - 2.5e-05 24.5 1.2 0.0002 21.6 1.2 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III LRR_4 PF12799.7 CBZ33118.1 - 1.5e-19 69.7 32.3 0.0033 17.8 0.5 12.0 9 3 4 14 14 14 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ33118.1 - 3.3e-11 42.8 30.3 4.7e-05 23.1 1.0 9.2 8 2 2 10 10 10 5 Leucine rich repeat LRR_6 PF13516.6 CBZ33118.1 - 0.00047 20.0 26.0 39 4.6 0.0 12.0 14 0 0 14 14 14 0 Leucine Rich repeat LRR_9 PF14580.6 CBZ33118.1 - 0.0012 18.4 14.1 0.45 10.0 0.1 5.0 4 2 1 5 5 5 3 Leucine-rich repeat DUF4363 PF14276.6 CBZ33118.1 - 0.28 11.3 0.8 9.6 6.4 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) RNA_pol_Rpb1_5 PF04998.17 CBZ33120.1 - 2.7e-58 197.5 0.0 8.8e-58 195.8 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CBZ33120.1 - 1.1e-48 165.6 0.0 2e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CBZ33120.1 - 8.9e-30 103.7 0.0 2e-29 102.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CBZ33120.1 - 2.1e-14 53.4 0.2 5.9e-14 51.9 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 CBZ33120.1 - 0.061 12.6 0.1 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 1 Amidase PF01425.21 CBZ33121.1 - 2.9e-60 204.5 0.0 1.5e-55 189.0 0.0 2.0 2 0 0 2 2 2 2 Amidase LSM PF01423.22 CBZ33122.1 - 5e-05 22.9 0.0 6.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.17 CBZ33122.1 - 0.043 13.7 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Arf PF00025.21 CBZ33123.1 - 5.7e-47 159.4 0.0 6.4e-47 159.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBZ33123.1 - 4e-10 39.4 0.0 5.2e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBZ33123.1 - 6.9e-10 38.8 0.1 2.6e-08 33.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CBZ33123.1 - 2.4e-09 37.4 0.0 3.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ33123.1 - 8.1e-09 35.3 0.0 9.2e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CBZ33123.1 - 4e-07 30.1 0.0 5.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CBZ33123.1 - 1e-06 28.2 2.4 0.01 15.0 0.5 2.8 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBZ33123.1 - 1.2e-06 28.0 0.1 1.5e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CBZ33123.1 - 1.9e-05 25.0 0.0 0.0011 19.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.18 CBZ33123.1 - 0.00025 20.6 0.1 0.00041 19.9 0.1 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ33123.1 - 0.0027 17.6 0.0 2 8.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 CBZ33123.1 - 0.01 15.4 0.0 3.3 7.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CBZ33123.1 - 0.019 15.5 0.0 0.035 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain PurL_C PF16904.5 CBZ33123.1 - 0.048 14.0 0.0 0.086 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine synthase II C-terminus ATP_bind_1 PF03029.17 CBZ33123.1 - 0.078 12.7 0.5 0.56 9.9 0.2 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Peptidase_M43 PF05572.13 CBZ33123.1 - 0.094 12.6 0.1 0.51 10.2 0.1 2.1 1 1 0 1 1 1 0 Pregnancy-associated plasma protein-A Septin PF00735.18 CBZ33123.1 - 0.13 11.6 0.1 0.23 10.7 0.0 1.4 2 0 0 2 2 2 0 Septin OTU PF02338.19 CBZ33124.1 - 4.7e-14 53.0 0.0 9.3e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CBZ33124.1 - 0.096 12.1 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase C65 Otubain EMG1 PF03587.14 CBZ33125.1 - 1.3e-57 194.6 0.0 2.5e-57 193.7 0.0 1.4 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase TRAPP PF04051.16 CBZ33126.1 - 1e-21 77.2 0.0 1.3e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component IQ PF00612.27 CBZ33127.1 - 0.061 13.1 0.4 0.19 11.6 0.4 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif FAM184 PF15665.5 CBZ33127.1 - 0.39 10.5 34.4 0.11 12.2 18.1 2.9 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B LCIB_C_CA PF18599.1 CBZ33127.1 - 1.5 8.0 5.1 0.59 9.4 1.7 1.9 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF4407 PF14362.6 CBZ33127.1 - 2.1 7.6 23.7 0.53 9.6 14.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3220 PF11516.8 CBZ33127.1 - 3.3 8.0 6.4 4 7.7 0.4 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF3120) DUF3450 PF11932.8 CBZ33127.1 - 3.7 6.8 24.1 0.2 10.9 9.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) zf-C4H2 PF10146.9 CBZ33128.1 - 0.00034 21.0 2.2 0.00044 20.6 2.2 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein Fmp27_WPPW PF10359.9 CBZ33128.1 - 0.045 12.6 5.4 0.06 12.2 5.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CLN3 PF02487.17 CBZ33128.1 - 3.8 6.5 5.1 5.6 5.9 5.1 1.2 1 0 0 1 1 1 0 CLN3 protein FmiP_Thoc5 PF09766.9 CBZ33128.1 - 4.4 6.5 16.3 2.2 7.5 14.1 1.5 1 1 1 2 2 2 0 Fms-interacting protein/Thoc5 Flagellar_rod PF05149.12 CBZ33129.1 - 1.1e-105 353.2 26.6 1.1e-105 353.2 26.6 2.1 2 0 0 2 2 2 1 Paraflagellar rod protein ING PF12998.7 CBZ33129.1 - 1.2 9.7 18.4 0.069 13.7 2.4 3.7 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding UPF0225 PF17775.1 CBZ33129.1 - 1.6 9.6 8.5 3.7 8.4 1.4 3.4 2 1 0 2 2 2 0 UPF0225 domain PAPS_reduct PF01507.19 CBZ33129.1 - 5.3 7.1 11.2 5.5 7.0 3.5 3.2 2 1 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Kinesin PF00225.23 CBZ33134.1 - 6.3e-78 262.0 0.0 9.6e-78 261.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ33134.1 - 2.8e-21 76.0 0.0 6.8e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF5082 PF16888.5 CBZ33134.1 - 0.027 14.7 14.4 0.066 13.5 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF3135 PF11333.8 CBZ33134.1 - 0.028 14.7 0.1 0.084 13.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) PhoH PF02562.16 CBZ33134.1 - 0.043 13.3 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran_CTD PF16326.5 CBZ33134.1 - 0.12 12.6 43.2 0.048 13.9 6.9 4.9 4 1 0 4 4 4 0 ABC transporter C-terminal domain DFF40 PF09230.10 CBZ33134.1 - 0.19 11.3 1.3 0.47 10.0 0.7 1.7 1 1 0 2 2 2 0 DNA fragmentation factor 40 kDa Occludin_ELL PF07303.13 CBZ33134.1 - 2.7 8.8 11.1 4.1 8.2 0.4 3.6 1 1 2 3 3 3 0 Occludin homology domain FAM76 PF16046.5 CBZ33134.1 - 4.6 6.5 12.7 6.2 6.1 2.8 2.3 1 1 1 2 2 2 0 FAM76 protein DUF1664 PF07889.12 CBZ33134.1 - 8.6 6.4 11.6 20 5.2 1.8 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) FtsH_ext PF06480.15 CBZ33135.1 - 0.085 13.2 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 FtsH Extracellular Phage_term_sma PF07141.11 CBZ33136.1 - 0.085 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit Phage_TAC_7 PF10109.9 CBZ33137.1 - 0.49 10.5 3.1 6.2 7.0 1.5 3.3 2 1 0 2 2 2 0 Phage tail assembly chaperone proteins, E, or 41 or 14 OTT_1508_deam PF14441.6 CBZ33138.1 - 0.077 13.0 0.2 10 6.2 0.0 2.2 2 0 0 2 2 2 0 OTT_1508-like deaminase ERO1 PF04137.15 CBZ33140.1 - 3.4e-88 296.2 0.0 4e-88 296.0 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DNA_pol_B PF00136.21 CBZ33141.1 - 2.4e-124 415.6 0.0 3.1e-124 415.2 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBZ33141.1 - 1.1e-38 133.3 0.0 2.4e-38 132.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 CBZ33141.1 - 0.006 16.3 1.9 3.3 7.4 0.0 2.4 1 1 1 2 2 2 2 DNA Polymerase alpha zinc finger DNA_pol_B_2 PF03175.13 CBZ33141.1 - 0.023 13.6 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral WD40 PF00400.32 CBZ33142.1 - 1.4e-14 54.2 4.0 0.022 15.6 0.0 7.2 8 0 0 8 8 8 4 WD domain, G-beta repeat Asp4 PF16996.5 CBZ33142.1 - 0.066 13.0 0.3 0.21 11.4 0.3 1.8 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 FAD_binding_8 PF08022.12 CBZ33143.1 - 0.034 14.2 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 FAD-binding domain Kinesin PF00225.23 CBZ33145.1 - 1.3e-70 238.0 0.0 2.7e-69 233.7 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ33145.1 - 1.8e-15 57.2 0.0 4e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 Microtubule binding PH_12 PF16457.5 CBZ33145.1 - 0.019 15.5 0.0 0.042 14.4 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain AAA_16 PF13191.6 CBZ33145.1 - 0.023 15.1 2.7 0.85 10.0 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CBZ33145.1 - 0.33 11.2 5.8 1.9 8.7 0.5 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CBZ33145.1 - 0.55 10.1 2.7 2.4 8.0 0.1 2.9 2 0 0 2 2 2 0 NACHT domain BST2 PF16716.5 CBZ33145.1 - 1.2 9.7 4.3 2.5 8.7 2.8 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 SMC_ScpA PF02616.14 CBZ33145.1 - 2.7 7.8 6.6 0.44 10.4 2.7 1.6 2 0 0 2 2 2 0 Segregation and condensation protein ScpA MIF4G PF02854.19 CBZ33147.1 - 1.3e-30 106.6 3.6 1.9e-30 106.1 3.6 1.3 1 0 0 1 1 1 1 MIF4G domain DUF5388 PF17363.2 CBZ33147.1 - 0.048 13.9 0.2 16 5.8 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5388) DUF2721 PF11026.8 CBZ33147.1 - 0.12 12.3 0.2 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Band_7 PF01145.25 CBZ33148.1 - 1.4e-23 83.9 2.1 2.3e-23 83.1 2.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CBZ33148.1 - 5.4e-05 22.4 1.3 6.9e-05 22.1 1.3 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Nop PF01798.18 CBZ33150.1 - 1.8e-13 50.5 2.5 3.4e-13 49.6 0.4 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CBZ33150.1 - 0.025 15.5 3.2 0.025 15.5 3.2 1.7 2 0 0 2 2 2 0 Prp31 C terminal domain eIF3_p135 PF12807.7 CBZ33151.1 - 0.0017 18.5 0.2 0.0045 17.0 0.2 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 CBZ33151.1 - 0.011 16.1 30.9 1.8 8.9 0.7 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ33151.1 - 0.022 14.7 7.3 23 5.0 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat IQ PF00612.27 CBZ33151.1 - 0.061 13.1 10.6 1.5 8.8 2.0 4.4 3 0 0 3 3 3 0 IQ calmodulin-binding motif TPR_7 PF13176.6 CBZ33151.1 - 0.21 11.7 1.2 64 3.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ33151.1 - 0.6 10.7 10.2 49 4.5 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat CLU PF13236.6 CBZ33152.1 - 2.8e-09 37.1 0.0 1.7e-07 31.3 0.0 2.9 1 1 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 CBZ33152.1 - 0.0015 18.6 0.1 0.0027 17.8 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.6 CBZ33153.1 - 1.6e-09 38.0 0.0 6.4e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CBZ33153.1 - 0.0017 18.4 1.8 0.0069 16.4 0.0 2.6 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_2 PF07719.17 CBZ33153.1 - 0.0077 16.3 0.1 0.31 11.3 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF3616 PF12275.8 CBZ33153.1 - 0.0085 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3616) ANAPC3 PF12895.7 CBZ33154.1 - 0.0034 17.6 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF1682 PF07946.14 CBZ33154.1 - 0.007 15.6 1.9 0.007 15.6 1.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) DUF3522 PF12036.8 CBZ33155.1 - 8.7e-43 146.8 14.4 1e-42 146.6 14.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) DUF2270 PF10028.9 CBZ33155.1 - 0.38 10.3 1.9 2.1 7.9 0.2 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2270) DUF3522 PF12036.8 CBZ33156.1 - 4.5e-41 141.2 5.9 5.9e-41 140.8 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) 7TMR-DISM_7TM PF07695.11 CBZ33156.1 - 0.03 14.2 1.0 0.03 14.2 1.0 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF2615 PF11027.8 CBZ33156.1 - 0.47 10.6 1.8 1.1 9.4 0.0 2.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) zf-RING_2 PF13639.6 CBZ33157.1 - 2.3e-10 40.6 7.8 5.1e-10 39.5 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBZ33157.1 - 2.3e-08 33.9 5.0 5.6e-08 32.7 5.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ33157.1 - 1.2e-07 31.5 6.7 2.3e-07 30.5 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ33157.1 - 2.3e-07 30.5 8.1 4.1e-07 29.7 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ33157.1 - 6.1e-07 29.6 11.7 9.4e-07 29.0 9.0 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBZ33157.1 - 7.5e-07 28.8 4.5 7.5e-07 28.8 4.5 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 CBZ33157.1 - 5.7e-06 26.1 3.5 1.3e-05 25.0 3.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ33157.1 - 2.4e-05 24.2 4.9 5.7e-05 23.0 4.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CBZ33157.1 - 4.6e-05 23.4 1.6 4.6e-05 23.4 1.6 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CBZ33157.1 - 8.3e-05 22.7 6.3 0.0002 21.4 6.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBZ33157.1 - 0.0046 16.8 7.2 0.27 11.1 8.2 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBZ33157.1 - 0.04 13.8 2.2 0.16 11.8 1.9 2.1 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Myc-LZ PF02344.15 CBZ33157.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Myc leucine zipper domain FANCL_C PF11793.8 CBZ33157.1 - 0.17 12.1 7.2 1.6 8.9 3.3 2.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CBZ33157.1 - 0.31 10.7 5.5 1 9.0 5.5 1.9 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type UBZ_FAAP20 PF15750.5 CBZ33157.1 - 0.78 9.7 5.3 0.94 9.5 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger CpXC PF14353.6 CBZ33157.1 - 0.8 9.8 4.3 2.8 8.0 4.3 1.9 1 1 0 1 1 1 0 CpXC protein zf-C3H2C3 PF17122.5 CBZ33157.1 - 1.2 9.2 6.6 6.2 6.9 6.5 2.3 1 1 1 2 2 2 0 Zinc-finger DnaJ PF00226.31 CBZ33158.1 - 4.6e-08 33.1 0.0 7.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF4160 PF13711.6 CBZ33159.1 - 0.035 14.4 0.8 0.1 12.9 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) TilS_C PF11734.8 CBZ33159.1 - 0.038 13.4 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 TilS substrate C-terminal domain Pkinase PF00069.25 CBZ33160.1 - 3.4e-68 229.9 0.0 4.8e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33160.1 - 1.1e-40 139.6 0.0 1.6e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ33160.1 - 5.4e-05 22.6 0.0 8.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.6 CBZ33160.1 - 0.00012 21.8 0.3 0.16 12.1 0.1 3.0 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 CBZ33160.1 - 0.0032 17.8 0.2 8.7 7.3 0.0 3.1 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_4 PF12799.7 CBZ33160.1 - 0.014 15.8 0.0 0.04 14.3 0.0 1.8 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) RIO1 PF01163.22 CBZ33160.1 - 0.021 14.4 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family LRR_8 PF13855.6 CBZ33160.1 - 0.047 13.5 0.2 0.64 9.8 0.5 2.2 1 1 0 1 1 1 0 Leucine rich repeat APH PF01636.23 CBZ33160.1 - 0.05 13.5 0.0 1.3 8.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ33160.1 - 0.069 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBZ33160.1 - 0.1 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arf PF00025.21 CBZ33161.1 - 1.5e-68 229.6 0.1 1.8e-68 229.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBZ33161.1 - 6.3e-13 49.0 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ33161.1 - 2.8e-11 43.2 0.0 3.2e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBZ33161.1 - 1e-10 41.3 0.1 5.6e-08 32.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CBZ33161.1 - 3e-09 36.7 0.0 3.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CBZ33161.1 - 1.4e-08 34.4 0.0 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ33161.1 - 2e-05 24.7 0.0 3.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ33161.1 - 0.017 14.7 0.8 0.087 12.4 0.8 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Guanylate_cyc PF00211.20 CBZ33162.1 - 1.8e-17 63.6 0.0 4.6e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Mid2 PF04478.12 CBZ33162.1 - 0.04 13.8 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Guanylate_cyc PF00211.20 CBZ33163.1 - 6.1e-18 65.1 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Peripla_BP_6 PF13458.6 CBZ33163.1 - 9.6e-06 25.5 0.3 4.6e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Periplasmic binding protein Peripla_BP_6 PF13458.6 CBZ33164.1 - 2.7e-07 30.6 0.1 9.3e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Periplasmic binding protein GTP_EFTU PF00009.27 CBZ33166.1 - 5.5e-51 172.9 0.0 9e-51 172.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ33166.1 - 8.6e-41 138.8 0.1 2.7e-40 137.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ33166.1 - 2.2e-15 56.8 1.0 4.6e-15 55.8 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ33166.1 - 1.2e-05 25.4 0.0 0.00052 20.1 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBZ33166.1 - 0.0038 16.7 0.1 0.024 14.1 0.0 2.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 CBZ33166.1 - 0.0051 16.7 1.0 0.011 15.6 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 FlpD PF02662.16 CBZ33166.1 - 0.0082 16.1 0.1 0.021 14.8 0.0 1.7 2 0 0 2 2 2 1 Methyl-viologen-reducing hydrogenase, delta subunit Semialdhyde_dhC PF02774.18 CBZ33166.1 - 0.022 14.8 0.1 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain gpW PF02831.15 CBZ33166.1 - 0.14 12.1 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 gpW CD52 PF15116.6 CBZ33168.1 - 0.18 11.8 2.7 1.6 8.9 2.7 2.7 1 0 0 1 1 1 0 CAMPATH-1 antigen YabA PF06156.13 CBZ33169.1 - 0.32 11.6 13.3 0.92 10.2 0.1 3.2 3 2 0 3 3 3 0 Initiation control protein YabA Tup_N PF08581.10 CBZ33169.1 - 1.3 9.4 12.1 0.58 10.5 3.0 2.8 2 0 0 2 2 2 0 Tup N-terminal DUF4407 PF14362.6 CBZ33169.1 - 2.8 7.2 26.8 0.66 9.3 3.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) YkyA PF10368.9 CBZ33169.1 - 6 6.5 11.8 0.63 9.7 6.8 1.9 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein DLIC PF05783.11 CBZ33169.1 - 7.9 5.2 8.6 0.65 8.8 2.6 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) TPR_2 PF07719.17 CBZ33170.1 - 1.3e-16 59.3 1.1 0.00031 20.6 0.0 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ33170.1 - 5.2e-08 33.1 0.5 0.073 13.4 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ33170.1 - 5.9e-08 32.2 5.5 0.012 15.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ33170.1 - 1e-07 31.6 3.2 0.19 12.0 0.1 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ33170.1 - 9.2e-06 26.1 0.3 7.9 7.6 0.0 4.1 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ33170.1 - 2e-05 24.3 3.3 0.046 13.8 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ33170.1 - 2.6e-05 24.6 0.2 0.00021 21.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ33170.1 - 2.7e-05 24.5 0.1 0.071 13.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ33170.1 - 0.00044 20.4 1.4 0.044 14.0 0.0 2.8 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBZ33170.1 - 0.00065 19.9 0.4 14 6.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ33170.1 - 0.003 17.4 1.8 16 5.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 CBZ33170.1 - 0.017 14.8 0.6 0.57 9.9 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain PknG_TPR PF16918.5 CBZ33170.1 - 0.025 13.3 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TPR_11 PF13414.6 CBZ33170.1 - 0.047 13.4 4.3 6 6.6 0.0 4.2 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.6 CBZ33170.1 - 0.15 12.7 1.9 3.4 8.4 0.0 3.7 3 2 1 4 4 3 0 Tetratricopeptide repeat Peptidase_M20 PF01546.28 CBZ33172.1 - 3.9e-11 43.0 0.1 5.5e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ33172.1 - 3.6e-08 33.3 0.0 7.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 CBZ33172.1 - 1.9e-05 23.9 0.1 0.0001 21.5 0.1 2.0 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 CBZ33172.1 - 4.5e-05 23.2 0.1 0.00014 21.6 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M28 Rep_3 PF01051.21 CBZ33172.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Initiator Replication protein FAP206 PF12018.8 CBZ33173.1 - 3e-07 30.2 0.0 2.2e-06 27.4 0.0 2.4 1 1 0 1 1 1 1 Domain of unknown function Kinesin PF00225.23 CBZ33174.1 - 8.6e-41 140.0 0.0 5.4e-39 134.0 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ33174.1 - 2.4e-08 34.0 0.0 8.7e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding Cast PF10174.9 CBZ33174.1 - 0.014 13.7 0.7 1.4 7.1 0.0 2.1 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone WD40 PF00400.32 CBZ33175.1 - 7.7e-26 89.8 9.7 4.5e-06 27.3 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ33175.1 - 6.5e-09 36.0 0.0 0.062 13.6 0.0 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ33175.1 - 2.5e-07 30.0 0.0 0.0054 15.7 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CBZ33175.1 - 8.9e-06 25.5 0.0 0.12 12.4 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Nup160 PF11715.8 CBZ33175.1 - 3.1e-05 22.8 0.7 0.25 9.9 0.0 3.6 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Frtz PF11768.8 CBZ33175.1 - 0.00038 18.9 0.0 0.0033 15.8 0.0 1.9 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 CBZ33175.1 - 0.069 11.7 0.1 0.48 8.9 0.0 2.3 3 0 0 3 3 3 0 Cytochrome D1 heme domain nos_propeller PF18764.1 CBZ33175.1 - 0.077 12.9 0.0 0.89 9.5 0.0 2.7 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat Proteasome_A_N PF10584.9 CBZ33175.1 - 0.2 11.4 0.3 9.4 6.0 0.1 2.9 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature RCC1 PF00415.18 CBZ33176.1 - 4.7e-55 184.0 28.5 1.8e-13 50.8 0.7 8.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ33176.1 - 4.9e-27 93.1 43.5 9.8e-12 44.4 3.1 8.6 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat BTB_2 PF02214.22 CBZ33176.1 - 5.1e-06 26.8 0.0 0.17 12.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain PALP PF00291.25 CBZ33177.1 - 9.4e-66 222.2 0.1 1.1e-65 221.9 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 2Fe-2S_thioredx PF01257.19 CBZ33179.1 - 1.2e-47 161.4 0.0 1.6e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF2293 PF10056.9 CBZ33179.1 - 0.18 12.1 0.1 0.34 11.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) Histone_H2A_C PF16211.5 CBZ33180.1 - 4.9e-12 45.4 1.1 1.1e-11 44.2 1.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBZ33180.1 - 1.2e-09 38.6 0.0 2.3e-09 37.7 0.0 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_3 PF13920.6 CBZ33181.1 - 8.3e-08 32.0 17.2 8.3e-08 32.0 17.2 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ33181.1 - 3.2e-07 30.1 15.4 3.2e-07 30.1 15.4 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ33181.1 - 4.1e-06 26.7 10.9 4.1e-06 26.7 10.9 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ33181.1 - 2.4e-05 24.1 14.6 2.4e-05 24.1 14.6 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ33181.1 - 0.00018 21.4 14.1 0.00018 21.4 14.1 2.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBZ33181.1 - 0.00028 21.0 15.8 0.00028 21.0 15.8 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 CBZ33181.1 - 0.00055 20.2 18.8 0.00055 20.2 18.8 3.5 4 0 0 4 4 4 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ33181.1 - 0.001 18.9 14.8 0.001 18.9 14.8 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBZ33181.1 - 0.029 14.2 12.5 0.095 12.6 12.5 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein LSM PF01423.22 CBZ33182.1 - 4.1e-08 32.8 0.1 3.9e-07 29.7 0.1 2.1 1 1 0 1 1 1 1 LSM domain DUF667 PF05018.13 CBZ33183.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF667) dsrm PF00035.26 CBZ33185.1 - 0.14 12.9 0.0 46 4.8 0.0 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif Dus PF01207.17 CBZ33187.1 - 5.5e-51 173.5 0.0 8.4e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Hid1 PF12722.7 CBZ33187.1 - 0.044 11.9 0.4 0.054 11.6 0.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein dCMP_cyt_deam_1 PF00383.23 CBZ33188.1 - 7.5e-12 45.0 2.1 1.1e-11 44.5 2.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CBZ33188.1 - 6.5e-09 36.1 2.8 4.4e-07 30.2 2.2 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CBZ33188.1 - 0.02 14.5 5.4 0.064 12.9 5.4 1.7 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Thioredoxin PF00085.20 CBZ33188.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Sec20 PF03908.13 CBZ33190.1 - 7e-05 22.7 0.8 7e-05 22.7 0.8 2.1 3 0 0 3 3 3 1 Sec20 V-SNARE_C PF12352.8 CBZ33190.1 - 0.00094 19.4 3.0 0.001 19.3 1.5 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Synaptobrevin PF00957.21 CBZ33190.1 - 0.0045 16.7 1.4 0.0045 16.7 1.4 2.2 1 1 1 2 2 2 1 Synaptobrevin SNARE PF05739.19 CBZ33190.1 - 0.009 16.0 1.1 0.023 14.7 1.1 1.7 1 0 0 1 1 1 1 SNARE domain V-SNARE PF05008.15 CBZ33190.1 - 0.036 14.4 3.9 0.063 13.7 0.1 2.6 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Mce4_CUP1 PF11887.8 CBZ33190.1 - 0.037 13.5 0.3 1.6 8.1 0.1 2.2 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF16 PF01519.16 CBZ33190.1 - 0.043 14.3 0.4 0.043 14.3 0.4 2.2 3 1 0 3 3 2 0 Protein of unknown function DUF16 Prominin PF05478.11 CBZ33190.1 - 0.05 11.6 2.5 0.09 10.7 1.0 1.8 2 0 0 2 2 2 0 Prominin Baculo_11_kDa PF06143.11 CBZ33190.1 - 0.05 13.2 0.3 0.1 12.2 0.3 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family Neur_chan_memb PF02932.16 CBZ33190.1 - 0.12 12.4 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Use1 PF09753.9 CBZ33190.1 - 1.1 8.9 9.5 28 4.3 9.5 2.2 1 1 0 1 1 1 0 Membrane fusion protein Use1 Spc7 PF08317.11 CBZ33190.1 - 1.4 7.8 6.9 0.48 9.2 1.6 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2203 PF09969.9 CBZ33190.1 - 2.6 8.8 6.6 17 6.2 1.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) EMP24_GP25L PF01105.24 CBZ33190.1 - 3.3 7.6 5.8 55 3.6 0.0 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD CENP-H PF05837.12 CBZ33190.1 - 8.4 6.8 10.8 2.4 8.6 2.5 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) YlqD PF11068.8 CBZ33190.1 - 9.6 6.6 12.4 0.56 10.6 0.7 2.7 3 1 0 3 3 3 0 YlqD protein Pkinase PF00069.25 CBZ33191.1 - 3e-61 207.1 0.0 5.7e-61 206.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33191.1 - 9.6e-40 136.5 0.0 8.3e-39 133.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ33191.1 - 8e-07 28.6 0.0 2.5e-06 27.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ33191.1 - 9.4e-06 24.6 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ33191.1 - 0.0033 17.4 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ33191.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ANTH PF07651.16 CBZ33191.1 - 0.015 14.3 0.0 0.041 12.9 0.0 1.6 1 0 0 1 1 1 0 ANTH domain zf-RING_2 PF13639.6 CBZ33192.1 - 2.1e-07 31.1 7.0 7.4e-07 29.4 7.0 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CBZ33192.1 - 3.1e-05 23.9 5.7 3.1e-05 23.9 5.7 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CBZ33192.1 - 0.0034 17.7 5.1 0.015 15.6 5.1 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBZ33192.1 - 0.0035 17.2 6.7 0.0035 17.2 6.7 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ33192.1 - 0.0069 16.3 9.1 0.022 14.7 9.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 CBZ33192.1 - 0.012 15.3 8.0 0.036 13.8 8.0 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBZ33192.1 - 0.064 13.1 13.3 0.22 11.4 10.9 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 CBZ33192.1 - 0.13 12.1 5.2 0.32 10.9 5.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CBZ33192.1 - 3.3 8.0 15.5 0.27 11.4 7.9 3.1 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING N6-adenineMlase PF10237.9 CBZ33194.1 - 6.2e-32 110.6 1.6 9.6e-32 110.0 1.6 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase MTS PF05175.14 CBZ33194.1 - 0.019 14.6 0.0 0.044 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 CBZ33194.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SoxD PF04267.12 CBZ33194.1 - 0.097 12.8 0.2 0.33 11.1 0.2 1.8 1 0 0 1 1 1 0 Sarcosine oxidase, delta subunit family FlxA PF14282.6 CBZ33194.1 - 0.28 11.2 3.1 0.85 9.6 2.2 2.2 1 1 1 2 2 2 0 FlxA-like protein HemY_N PF07219.13 CBZ33195.1 - 8.7 6.6 8.5 0.17 12.1 0.7 2.1 2 0 0 2 2 2 0 HemY protein N-terminus Leu_zip PF15294.6 CBZ33196.1 - 0.00071 19.2 4.4 0.0019 17.8 4.4 1.7 1 0 0 1 1 1 1 Leucine zipper BLOC1_2 PF10046.9 CBZ33196.1 - 1.2 9.5 4.3 0.49 10.7 0.9 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 CBZ33196.1 - 3.2 6.7 11.3 18 4.3 10.7 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DnaJ PF00226.31 CBZ33198.1 - 4.3e-10 39.6 0.0 7.4e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PhzC-PhzF PF02567.16 CBZ33201.1 - 2.1e-34 119.3 1.5 1.9e-23 83.3 0.1 4.6 3 1 0 3 3 3 3 Phenazine biosynthesis-like protein Sigma70_r4 PF04545.16 CBZ33201.1 - 0.0093 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Pkinase PF00069.25 CBZ33202.1 - 1.7e-58 198.1 0.0 2.7e-58 197.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33202.1 - 7.1e-39 133.7 0.0 9.7e-28 97.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase BUD22 PF09073.10 CBZ33202.1 - 0.0033 16.8 29.2 0.006 16.0 29.2 1.3 1 0 0 1 1 1 1 BUD22 Pkinase_fungal PF17667.1 CBZ33202.1 - 0.0073 15.1 0.0 0.026 13.3 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 CBZ33202.1 - 0.046 12.7 0.0 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CBZ33202.1 - 0.059 12.7 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.16 CBZ33202.1 - 0.071 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 CBZ33202.1 - 0.18 11.1 0.1 0.46 9.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Apt1 PF10351.9 CBZ33202.1 - 0.4 9.5 6.8 0.67 8.7 6.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 CBZ33202.1 - 0.76 8.0 16.3 1.3 7.2 16.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CBZ33202.1 - 1.2 7.3 24.3 1.6 6.8 24.3 1.1 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 CBZ33202.1 - 2.2 6.6 18.2 3.3 6.1 18.2 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIF_alpha PF05793.12 CBZ33202.1 - 3.7 6.0 24.6 7.3 5.1 24.6 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SDA1 PF05285.12 CBZ33202.1 - 5.7 6.3 27.4 8.4 5.7 27.4 1.2 1 0 0 1 1 1 0 SDA1 Spc7 PF08317.11 CBZ33206.1 - 0.0025 16.8 7.9 0.0025 16.8 7.9 4.3 3 1 1 4 4 4 2 Spc7 kinetochore protein BCAS2 PF05700.11 CBZ33206.1 - 0.0025 17.5 8.9 0.0025 17.5 8.9 5.0 4 1 1 6 6 6 2 Breast carcinoma amplified sequence 2 (BCAS2) Sirohm_synth_C PF14823.6 CBZ33206.1 - 0.014 15.1 0.1 0.077 12.6 0.0 2.4 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal WD40_alt PF14077.6 CBZ33206.1 - 0.4 10.6 1.9 2.2 8.2 0.0 2.9 3 0 0 3 3 3 0 Alternative WD40 repeat motif zf-ZPR1 PF03367.13 CBZ33206.1 - 1.2 9.0 6.4 0.66 9.8 1.1 2.9 1 1 2 3 3 3 0 ZPR1 zinc-finger domain Golgin_A5 PF09787.9 CBZ33206.1 - 8.6 5.7 51.8 0.012 15.1 17.1 3.4 2 1 1 3 3 3 0 Golgin subfamily A member 5 AAA PF00004.29 CBZ33207.1 - 4.3e-09 36.9 0.0 5.1e-08 33.4 0.0 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ33207.1 - 2.3e-06 28.1 0.1 1.3e-05 25.7 0.1 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CBZ33207.1 - 4.4e-06 26.7 0.0 0.0014 18.6 0.0 3.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CBZ33207.1 - 2.8e-05 24.1 0.1 0.00094 19.1 0.0 2.6 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 CBZ33207.1 - 4.5e-05 23.7 0.1 0.00025 21.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ33207.1 - 0.00016 21.9 0.1 0.0006 20.1 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ33207.1 - 0.00033 21.2 0.0 0.0011 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CBZ33207.1 - 0.00036 20.8 0.1 0.0021 18.4 0.0 2.4 2 0 0 2 2 1 1 AAA C-terminal domain AAA_19 PF13245.6 CBZ33207.1 - 0.00099 19.5 0.0 0.0027 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CBZ33207.1 - 0.0016 18.4 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase RuvB_N PF05496.12 CBZ33207.1 - 0.0017 18.1 0.1 0.0043 16.8 0.1 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBZ33207.1 - 0.0019 18.4 0.0 0.0019 18.4 0.0 2.7 3 1 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 CBZ33207.1 - 0.0028 17.6 0.1 0.0063 16.4 0.1 1.5 1 0 0 1 1 1 1 NTPase AAA_25 PF13481.6 CBZ33207.1 - 0.0078 15.8 0.0 0.024 14.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CBZ33207.1 - 0.028 14.8 0.7 0.099 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CBZ33207.1 - 0.047 13.7 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CBZ33207.1 - 0.073 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 CBZ33207.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase NACHT PF05729.12 CBZ33207.1 - 0.14 12.0 0.0 0.5 10.3 0.0 2.0 1 0 0 1 1 1 0 NACHT domain SKI PF01202.22 CBZ33207.1 - 0.16 12.1 0.4 0.64 10.1 0.0 2.3 2 0 0 2 2 1 0 Shikimate kinase cobW PF02492.19 CBZ33207.1 - 0.19 11.3 0.0 0.43 10.1 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Polyoma_lg_T_C PF06431.11 CBZ33207.1 - 0.21 10.4 0.0 0.4 9.5 0.0 1.3 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus AAA_7 PF12775.7 CBZ33207.1 - 0.23 10.9 0.0 0.56 9.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CBZ33207.1 - 0.23 11.8 0.0 0.74 10.2 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_30 PF13604.6 CBZ33207.1 - 0.26 11.0 11.8 0.022 14.5 2.8 3.4 3 1 0 3 3 3 0 AAA domain SUIM_assoc PF16619.5 CBZ33207.1 - 3.1 7.9 5.5 61 3.8 3.0 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 CBZ33208.1 - 1.4e-12 47.2 0.8 1.5e-08 34.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ33208.1 - 0.0026 17.4 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AsnC_trans_reg PF01037.21 CBZ33208.1 - 0.11 12.5 0.0 4.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain SET_assoc PF11767.8 CBZ33208.1 - 0.14 11.8 0.1 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 CBZ33208.1 - 0.17 11.9 0.0 5.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Mito_fiss_reg PF05308.11 CBZ33208.1 - 0.26 11.4 3.7 0.093 12.8 0.5 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator ELF PF03317.13 CBZ33209.1 - 0.031 14.3 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 ELF protein Arg_decarbox_C PF17944.1 CBZ33209.1 - 0.17 12.5 1.0 1.7 9.3 0.1 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension Fib_alpha PF08702.10 CBZ33210.1 - 0.021 15.0 2.3 3.1 8.0 2.0 2.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Metallophos PF00149.28 CBZ33211.1 - 2.9e-06 28.0 0.0 6.8e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase DUF2201_N PF13203.6 CBZ33211.1 - 0.063 12.9 4.4 0.21 11.2 4.4 1.7 1 1 0 1 1 1 0 Putative metallopeptidase domain DUF4381 PF14316.6 CBZ33212.1 - 2.4 8.4 11.8 0.62 10.3 1.7 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) Cation_ATPase_C PF00689.21 CBZ33213.1 - 2.4e-40 138.2 4.9 5.4e-40 137.0 4.9 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CBZ33213.1 - 1.8e-32 112.3 0.8 4.2e-32 111.1 0.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBZ33213.1 - 1.1e-26 92.8 0.0 2.3e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBZ33213.1 - 5.7e-16 59.4 3.9 2.8e-14 53.9 3.9 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CBZ33213.1 - 6.7e-13 48.1 0.0 1.9e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBZ33213.1 - 0.00016 21.5 0.6 0.00031 20.6 0.6 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACBP PF00887.19 CBZ33214.1 - 4.1e-30 103.8 0.2 1.9e-16 60.1 0.0 3.0 2 0 0 2 2 2 2 Acyl CoA binding protein ACBP PF00887.19 CBZ33215.1 - 3.6e-27 94.4 0.5 4.2e-27 94.2 0.5 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Ldl_recept_b PF00058.17 CBZ33216.1 - 0.095 13.2 0.0 16 6.1 0.1 3.5 3 0 0 3 3 3 0 Low-density lipoprotein receptor repeat class B ACBP PF00887.19 CBZ33217.1 - 6.9e-28 96.7 0.5 7.7e-28 96.5 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Abhydrolase_6 PF12697.7 CBZ33219.1 - 3.9e-05 24.4 0.3 5.3e-05 23.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBZ33219.1 - 0.00087 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cas_GSU0053 PF09617.10 CBZ33219.1 - 0.0067 16.4 0.3 0.025 14.6 0.3 1.8 1 1 0 1 1 1 1 CRISPR-associated protein GSU0053 (Cas_GSU0053) PGAP1 PF07819.13 CBZ33219.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein EF-hand_13 PF17958.1 CBZ33220.1 - 2.1e-22 78.7 0.1 1.2e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CBZ33220.1 - 2.1e-19 69.7 0.4 4e-15 56.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ33220.1 - 1.3e-06 27.8 0.1 0.00032 20.4 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 CBZ33220.1 - 8.7e-05 21.8 0.1 0.00059 19.2 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 CBZ33220.1 - 0.00026 20.3 0.0 0.003 17.0 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 CBZ33220.1 - 0.021 14.6 0.9 0.34 10.8 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain pair VASt PF16016.5 CBZ33221.1 - 0.0064 16.9 0.0 0.0093 16.4 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CBZ33222.1 - 8.6e-09 35.3 0.5 8.6e-09 35.3 0.5 2.3 2 0 0 2 2 2 1 GRAM domain VASt PF16016.5 CBZ33222.1 - 0.0093 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Pkinase PF00069.25 CBZ33224.1 - 4.5e-68 229.5 0.0 5.5e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33224.1 - 5.9e-39 133.9 0.0 7.5e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ33224.1 - 1.9e-09 37.3 0.0 3.5e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ33224.1 - 9.3e-05 21.4 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CBZ33224.1 - 0.00015 20.8 0.2 0.00022 20.3 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBZ33224.1 - 0.00055 19.9 1.4 0.015 15.2 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBZ33224.1 - 0.054 12.5 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF4404 PF14357.6 CBZ33224.1 - 0.11 13.2 1.8 0.54 10.9 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) VID27 PF08553.10 CBZ33225.1 - 2.7e-30 105.7 0.0 4.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Pkinase PF00069.25 CBZ33228.1 - 1.6e-22 80.1 0.0 3.7e-12 46.2 0.0 4.1 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33228.1 - 0.00016 21.1 0.0 0.029 13.7 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase NT5C PF06941.12 CBZ33229.1 - 0.011 15.7 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) DUF4482 PF14818.6 CBZ33230.1 - 0.0089 16.9 0.7 0.064 14.1 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4482) FH2 PF02181.23 CBZ33230.1 - 0.25 10.4 3.4 0.72 8.9 0.1 2.5 3 0 0 3 3 3 0 Formin Homology 2 Domain SR-25 PF10500.9 CBZ33230.1 - 6.6 6.3 13.7 0.36 10.4 0.1 2.9 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein Methyltransf_16 PF10294.9 CBZ33231.1 - 1.5e-18 67.1 0.1 5.1e-14 52.4 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 CBZ33231.1 - 0.17 11.4 0.3 0.39 10.3 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Myb_DNA-binding PF00249.31 CBZ33232.1 - 6.2e-19 67.9 4.0 1.6e-10 41.0 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBZ33232.1 - 5e-14 52.3 10.3 4.6e-08 33.2 0.3 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Peptidase_S9 PF00326.21 CBZ33232.1 - 0.011 15.2 2.0 1.3 8.4 0.1 2.8 3 0 0 3 3 3 0 Prolyl oligopeptidase family RNA_pol_Rpb2_7 PF04560.20 CBZ33232.1 - 0.15 12.5 0.1 6.9 7.1 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 7 Myb_DNA-bind_4 PF13837.6 CBZ33232.1 - 0.88 10.0 7.0 3.9 7.9 0.1 3.7 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain IMPDH PF00478.25 CBZ33234.1 - 7.8e-144 478.9 4.6 9.3e-144 478.7 4.6 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CBZ33234.1 - 2.4e-12 47.1 0.1 6.3e-05 23.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 CBZ33234.1 - 2.7e-07 30.3 9.8 0.00038 19.9 7.6 2.6 2 1 0 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 CBZ33234.1 - 3.9e-07 29.4 6.6 7.4e-07 28.5 6.6 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CBZ33234.1 - 0.00039 20.0 2.6 0.023 14.2 0.1 2.4 1 1 0 2 2 2 2 Histidine biosynthesis protein Glu_synthase PF01645.17 CBZ33234.1 - 0.0014 17.9 4.9 0.0028 16.8 4.9 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 CBZ33234.1 - 0.0034 16.7 4.6 0.024 13.9 0.5 2.3 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 CBZ33234.1 - 0.0043 16.4 0.8 0.0043 16.4 0.8 2.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Beta_elim_lyase PF01212.21 CBZ33234.1 - 0.016 14.5 0.4 0.03 13.6 0.4 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase NanE PF04131.14 CBZ33234.1 - 0.17 11.0 3.9 4.1 6.5 0.2 3.1 3 1 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Lysine_decarbox PF03641.14 CBZ33235.1 - 7.1e-28 97.3 0.2 1.1e-27 96.7 0.2 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CBZ33235.1 - 7.9e-11 41.8 0.5 1.3e-10 41.1 0.5 1.2 1 0 0 1 1 1 1 SLOG cluster4 family ABM PF03992.16 CBZ33235.1 - 6.9e-09 35.7 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Kinesin PF00225.23 CBZ33236.1 - 1.2e-103 346.6 0.1 1.2e-103 346.6 0.1 2.5 2 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ33236.1 - 3.2e-24 85.6 1.8 6.3e-24 84.6 0.0 2.5 2 0 0 2 2 2 1 Microtubule binding ATG16 PF08614.11 CBZ33236.1 - 0.00046 20.5 25.4 0.00046 20.5 25.4 5.9 1 1 4 5 5 5 1 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 CBZ33236.1 - 0.00072 18.3 7.2 0.00072 18.3 7.2 4.4 3 1 1 5 5 5 1 AAA domain G-patch PF01585.23 CBZ33238.1 - 4.4e-13 48.9 0.5 1e-12 47.7 0.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CBZ33238.1 - 0.0025 17.9 0.3 0.0079 16.3 0.3 1.9 1 0 0 1 1 1 1 G-patch domain Macoilin PF09726.9 CBZ33238.1 - 0.022 13.4 4.3 0.023 13.3 4.3 1.0 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 CBZ33238.1 - 0.41 8.4 3.5 0.48 8.1 3.5 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 CBZ33238.1 - 1.9 6.5 7.9 2.3 6.2 7.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Presenilin PF01080.17 CBZ33238.1 - 3 6.5 7.0 3.8 6.2 7.0 1.0 1 0 0 1 1 1 0 Presenilin Peroxin-3 PF04882.12 CBZ33238.1 - 7.3 5.5 7.3 9.4 5.1 7.3 1.1 1 0 0 1 1 1 0 Peroxin-3 DBR1 PF05011.13 CBZ33240.1 - 3.7e-08 33.9 0.0 6.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CBZ33240.1 - 0.00024 21.6 0.0 0.00073 20.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-synt_10 PF05176.14 CBZ33241.1 - 0.0027 17.0 0.0 0.0056 16.0 0.0 1.6 1 0 0 1 1 1 1 ATP10 protein MdcG PF10620.9 CBZ33242.1 - 0.0053 16.6 0.2 0.0073 16.1 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosyl-dephospho-CoA transferase MdcG Hypoth_Ymh PF09509.10 CBZ33242.1 - 0.051 13.5 1.5 0.058 13.3 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) DUF1935 PF09149.10 CBZ33244.1 - 1.4e-34 118.6 0.0 2.8e-34 117.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) META PF03724.16 CBZ33244.1 - 1.1e-27 96.1 1.3 1.3e-09 37.9 0.0 3.2 3 0 0 3 3 3 3 META domain YabA PF06156.13 CBZ33244.1 - 0.065 13.9 0.3 0.96 10.1 0.0 2.6 3 0 0 3 3 3 0 Initiation control protein YabA Fzo_mitofusin PF04799.13 CBZ33245.1 - 0.13 11.9 0.2 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 fzo-like conserved region META PF03724.16 CBZ33246.1 - 1.7e-10 40.8 0.0 2e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 META domain LRR_6 PF13516.6 CBZ33247.1 - 1.6e-12 46.4 0.1 0.24 11.5 0.1 5.7 5 0 0 5 5 5 4 Leucine Rich repeat LRR_4 PF12799.7 CBZ33247.1 - 4.1e-06 27.0 1.4 0.64 10.5 0.1 4.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ33247.1 - 0.0059 17.0 0.0 1.1e+02 4.0 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 CBZ33247.1 - 0.065 13.0 5.9 16 5.4 0.2 4.4 3 2 0 3 3 3 0 Leucine rich repeat ZNRF_3_ecto PF18212.1 CBZ33247.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 ZNRF-3 Ectodomain Acyltransferase PF01553.21 CBZ33248.1 - 1.1e-13 50.9 0.0 2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CBZ33248.1 - 0.00026 21.0 0.1 0.0017 18.4 0.0 2.4 2 1 0 2 2 2 1 Acyltransferase C-terminus Ndc1_Nup PF09531.10 CBZ33248.1 - 0.13 10.9 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec63 PF02889.16 CBZ33249.1 - 8.9e-56 188.9 0.0 1e-50 172.3 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CBZ33249.1 - 4.2e-32 111.3 0.8 2.2e-24 86.2 0.5 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CBZ33249.1 - 3.7e-12 46.6 0.0 2.3e-10 40.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ33249.1 - 1.9e-08 34.6 0.0 1.1e-06 29.0 0.0 2.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_16 PF13191.6 CBZ33249.1 - 0.00028 21.3 2.6 0.58 10.5 0.3 3.8 4 0 0 4 4 4 2 AAA ATPase domain Helicase_PWI PF18149.1 CBZ33249.1 - 0.014 15.6 0.0 0.043 14.0 0.0 1.9 1 0 0 1 1 1 0 N-terminal helicase PWI domain AAA_19 PF13245.6 CBZ33249.1 - 0.056 13.8 0.7 0.85 10.0 0.8 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBZ33249.1 - 0.12 11.8 0.6 4.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Sec63 PF02889.16 CBZ33250.1 - 8.9e-56 188.9 0.0 1e-50 172.3 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CBZ33250.1 - 4.2e-32 111.3 0.8 2.2e-24 86.2 0.5 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CBZ33250.1 - 3.7e-12 46.6 0.0 2.3e-10 40.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ33250.1 - 1.9e-08 34.6 0.0 1.1e-06 29.0 0.0 2.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_16 PF13191.6 CBZ33250.1 - 0.00028 21.3 2.6 0.58 10.5 0.3 3.8 4 0 0 4 4 4 2 AAA ATPase domain Helicase_PWI PF18149.1 CBZ33250.1 - 0.014 15.6 0.0 0.043 14.0 0.0 1.9 1 0 0 1 1 1 0 N-terminal helicase PWI domain AAA_19 PF13245.6 CBZ33250.1 - 0.056 13.8 0.7 0.85 10.0 0.8 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CBZ33250.1 - 0.12 11.8 0.6 4.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FH2 PF02181.23 CBZ33251.1 - 3e-50 171.4 0.0 4.8e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Med9 PF07544.13 CBZ33251.1 - 0.00013 22.0 0.3 0.00046 20.2 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 CUE PF02845.16 CBZ33251.1 - 0.0047 16.6 0.0 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 CUE domain CorA PF01544.18 CBZ33251.1 - 0.0084 15.5 0.1 0.021 14.1 0.1 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RPW8 PF05659.11 CBZ33251.1 - 0.035 13.8 0.3 0.078 12.7 0.3 1.6 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF2096 PF09869.9 CBZ33251.1 - 0.22 11.6 1.0 0.69 10.0 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2096) PCIF1_WW PF12237.8 CBZ33252.1 - 9e-34 116.5 0.1 1.7e-32 112.4 0.1 2.6 2 1 0 2 2 2 1 Phosphorylated CTD interacting factor 1 WW domain PDEase_I PF00233.19 CBZ33253.1 - 5.9e-15 55.6 0.2 1.4e-14 54.4 0.2 1.6 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Mak10 PF04112.13 CBZ33255.1 - 3.6e-07 29.8 0.1 1.8e-05 24.3 0.1 2.5 1 1 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF826 PF05696.11 CBZ33255.1 - 0.01 15.9 1.2 0.43 10.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF826) PI3_PI4_kinase PF00454.27 CBZ33256.1 - 0.0022 17.8 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Autoind_bind PF03472.15 CBZ33257.1 - 0.082 12.4 0.0 0.26 10.8 0.0 1.8 2 0 0 2 2 2 0 Autoinducer binding domain Abhydrolase_1 PF00561.20 CBZ33258.1 - 8.7e-20 71.4 0.1 1.9e-15 57.2 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ33258.1 - 5.5e-09 35.6 0.0 3e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ33258.1 - 1.3e-07 32.5 1.0 1.8e-07 32.0 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 CBZ33258.1 - 0.00065 19.8 0.0 0.0013 18.9 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 CBZ33258.1 - 0.0031 17.2 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 CBZ33258.1 - 0.0079 15.7 0.0 0.08 12.4 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ndr PF03096.14 CBZ33258.1 - 0.045 12.4 0.0 0.095 11.4 0.0 1.4 2 0 0 2 2 2 0 Ndr family Abhydrolase_2 PF02230.16 CBZ33258.1 - 0.12 12.2 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 CBZ33258.1 - 0.16 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase BAAT_C PF08840.11 CBZ33258.1 - 0.24 11.3 0.0 1.8 8.5 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal GlcNAc PF11397.8 CBZ33259.1 - 9.1e-141 469.4 0.0 1.1e-140 469.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase (GlcNAc) DUF2452 PF10504.9 CBZ33259.1 - 0.055 12.9 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) RPA_C PF08784.11 CBZ33260.1 - 0.39 11.4 4.8 0.66 10.7 2.2 2.8 2 0 0 2 2 2 0 Replication protein A C terminal Abhydrolase_1 PF00561.20 CBZ33261.1 - 2.1e-16 60.3 0.0 1.2e-14 54.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBZ33261.1 - 1.5e-09 38.8 0.9 3.9e-09 37.4 0.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBZ33261.1 - 3.3e-07 29.8 0.1 0.015 14.5 0.1 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Esterase_phd PF10503.9 CBZ33261.1 - 5.8e-05 22.7 0.6 0.1 12.1 0.1 2.4 2 0 0 2 2 2 2 Esterase PHB depolymerase Abhydrolase_4 PF08386.10 CBZ33261.1 - 0.00014 22.0 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Ndr PF03096.14 CBZ33261.1 - 0.00086 18.1 0.0 0.0014 17.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 CBZ33261.1 - 0.0025 17.7 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_3 PF07859.13 CBZ33261.1 - 0.021 14.7 0.0 0.85 9.4 0.0 2.6 3 0 0 3 3 3 0 alpha/beta hydrolase fold Esterase PF00756.20 CBZ33261.1 - 0.026 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.13 CBZ33261.1 - 0.044 13.4 0.0 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 CBZ33261.1 - 0.069 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Patatin PF01734.22 CBZ33261.1 - 0.1 12.7 0.5 0.18 12.0 0.5 1.5 1 1 0 1 1 1 0 Patatin-like phospholipase Peptidase_S9 PF00326.21 CBZ33261.1 - 0.12 11.8 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CBZ33262.1 - 7e-20 71.7 0.0 7.9e-19 68.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ33262.1 - 2.5e-14 53.1 0.0 4.2e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ33262.1 - 1.5e-11 45.3 2.3 2.9e-11 44.4 2.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 CBZ33262.1 - 8.2e-06 25.5 0.2 0.0016 18.0 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Esterase PF00756.20 CBZ33262.1 - 0.00011 21.9 0.0 0.00027 20.6 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Ndr PF03096.14 CBZ33262.1 - 0.00097 17.9 0.0 0.004 15.9 0.0 1.8 2 0 0 2 2 2 1 Ndr family Abhydrolase_4 PF08386.10 CBZ33262.1 - 0.0072 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.16 CBZ33262.1 - 0.009 15.8 0.0 0.64 9.8 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 CBZ33262.1 - 0.036 13.6 0.0 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family FIST PF08495.10 CBZ33262.1 - 0.14 12.1 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 FIST N domain Abhydrolase_1 PF00561.20 CBZ33264.1 - 2.2e-17 63.6 0.0 4.1e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ33264.1 - 1.8e-10 40.5 0.0 5.8e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ33264.1 - 5.5e-07 30.4 4.3 5.5e-07 30.4 4.3 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 CBZ33264.1 - 0.0025 17.9 0.0 0.01 15.9 0.0 2.0 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 CBZ33264.1 - 0.0046 17.1 0.0 0.0085 16.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 CBZ33264.1 - 0.023 14.2 0.0 1.5 8.3 0.0 2.8 3 0 0 3 3 3 0 Prolyl oligopeptidase family Esterase PF00756.20 CBZ33264.1 - 0.091 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DUF2048 PF09752.9 CBZ33264.1 - 0.16 11.0 0.3 0.34 10.0 0.3 1.4 1 0 0 1 1 1 0 Abhydrolase domain containing 18 ThiG PF05690.14 CBZ33264.1 - 0.59 9.4 11.6 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PLAC8 PF04749.17 CBZ33265.1 - 0.009 17.0 8.2 0.009 17.0 8.2 1.8 2 0 0 2 2 2 1 PLAC8 family DUF4570 PF15134.6 CBZ33266.1 - 0.005 16.8 4.7 0.0099 15.9 4.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) Cortex-I_coil PF09304.10 CBZ33266.1 - 0.4 10.9 3.3 0.7 10.1 3.3 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil UCH PF00443.29 CBZ33267.1 - 4.6e-16 59.1 0.0 6.4e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ33267.1 - 7.2e-07 29.1 0.0 2.4e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Steroid_dh PF02544.16 CBZ33268.1 - 5.6e-25 88.1 1.4 9.5e-10 38.6 0.0 4.3 4 0 0 4 4 4 4 3-oxo-5-alpha-steroid 4-dehydrogenase Kinesin PF00225.23 CBZ33269.1 - 4e-86 289.0 0.1 6.2e-86 288.3 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ33269.1 - 7.9e-24 84.3 0.0 2.2e-23 82.9 0.0 1.7 2 0 0 2 2 2 1 Microtubule binding Calpain_III PF01067.22 CBZ33269.1 - 8.8e-15 55.2 0.0 3.4e-11 43.6 0.0 2.7 2 0 0 2 2 2 2 Calpain large subunit, domain III Arm PF00514.23 CBZ33269.1 - 5.4e-07 29.4 3.1 0.36 10.9 0.1 5.2 5 1 0 5 5 5 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CBZ33269.1 - 0.42 10.7 2.6 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain Methyltr_RsmB-F PF01189.17 CBZ33271.1 - 1.4e-27 96.6 0.0 1.6e-17 63.8 0.0 3.9 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F WW PF00397.26 CBZ33272.1 - 3.5e-10 39.8 0.2 7.3e-10 38.8 0.2 1.6 1 0 0 1 1 1 1 WW domain DUF746 PF05344.11 CBZ33272.1 - 0.011 15.6 0.1 0.078 12.8 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) XRN_N PF03159.18 CBZ33273.1 - 2.3e-71 240.1 0.0 3.4e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus UDPGP PF01704.18 CBZ33274.1 - 1.9e-10 40.0 0.0 3.7e-10 39.0 0.0 1.4 2 0 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase DUF664 PF04978.12 CBZ33275.1 - 0.69 10.3 7.8 0.37 11.2 4.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF664) PRKG1_interact PF15898.5 CBZ33276.1 - 7 7.6 8.5 17 6.4 4.8 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain ATG16 PF08614.11 CBZ33278.1 - 0.0046 17.2 3.9 0.0046 17.2 3.9 4.1 4 1 1 5 5 5 2 Autophagy protein 16 (ATG16) ADIP PF11559.8 CBZ33278.1 - 0.01 15.9 1.6 0.01 15.9 1.6 2.9 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CtIP_N PF10482.9 CBZ33278.1 - 0.044 13.8 0.2 0.044 13.8 0.2 1.9 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain UPF0242 PF06785.11 CBZ33278.1 - 0.16 12.0 2.3 0.54 10.3 2.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BRE1 PF08647.11 CBZ33278.1 - 0.25 11.4 4.8 0.16 12.0 0.2 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Sugarporin_N PF11471.8 CBZ33278.1 - 0.62 10.1 4.1 0.25 11.3 0.6 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Macoilin PF09726.9 CBZ33278.1 - 0.69 8.4 22.1 0.0085 14.7 6.6 3.0 3 0 0 3 3 3 0 Macoilin family DUF3584 PF12128.8 CBZ33278.1 - 0.89 7.0 7.7 0.66 7.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) CLZ PF16526.5 CBZ33278.1 - 0.94 9.9 6.2 4.4 7.7 1.1 2.5 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaC_arch PF05377.11 CBZ33278.1 - 1.4 9.4 5.5 8.1 6.9 0.6 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 CBZ33278.1 - 2.6 8.3 8.1 7.7 6.8 1.1 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 CBZ33278.1 - 3.1 8.5 8.9 2.2 8.9 0.4 3.5 3 1 0 3 3 3 0 SlyX Cnn_1N PF07989.11 CBZ33278.1 - 7.6 6.8 6.4 15 5.8 0.4 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Motile_Sperm PF00635.26 CBZ33279.1 - 2e-10 40.4 0.0 3.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ECM1 PF05782.11 CBZ33279.1 - 6.7 5.5 14.5 10 4.9 14.5 1.2 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Histone PF00125.24 CBZ33280.1 - 2.1e-09 37.9 0.8 2.8e-09 37.4 0.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ33280.1 - 0.017 15.4 0.6 0.03 14.6 0.6 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4661 PF15576.6 CBZ33281.1 - 0.15 12.0 0.4 0.41 10.5 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) TPR_2 PF07719.17 CBZ33282.1 - 1.7e-07 30.8 1.2 0.19 11.9 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ33282.1 - 5e-05 23.9 6.2 0.013 16.1 0.3 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ33282.1 - 7.5e-05 22.8 0.0 0.88 10.1 0.0 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ33282.1 - 0.0001 22.8 20.2 1 10.4 0.1 7.7 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ33282.1 - 0.00089 19.3 0.0 3.6 8.0 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ33282.1 - 0.019 14.8 0.0 3.3 7.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ33282.1 - 5.2 7.4 7.8 5.1 7.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat GNAT_acetyltr_2 PF13718.6 CBZ33283.1 - 2e-81 272.7 0.0 5.1e-81 271.4 0.0 1.7 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 CBZ33283.1 - 1.9e-59 200.5 0.0 5.8e-59 198.9 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 CBZ33283.1 - 6.5e-30 102.9 0.1 1.7e-29 101.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.6 CBZ33283.1 - 4.2e-22 79.0 0.0 2.5e-21 76.5 0.0 2.0 1 1 0 1 1 1 1 Possible tRNA binding domain AAA_30 PF13604.6 CBZ33283.1 - 2.1e-05 24.4 0.1 0.00036 20.3 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBZ33283.1 - 0.0012 19.2 0.8 0.011 16.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain DUF5585 PF17823.1 CBZ33283.1 - 0.071 12.1 1.5 0.13 11.1 1.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5585) Oscp1 PF10188.9 CBZ33284.1 - 2.1e-56 190.8 0.2 3.1e-56 190.2 0.2 1.3 1 0 0 1 1 1 1 Organic solute transport protein 1 Sterol-sensing PF12349.8 CBZ33284.1 - 0.031 14.1 0.5 0.051 13.4 0.5 1.3 1 0 0 1 1 1 0 Sterol-sensing domain of SREBP cleavage-activation eIF2A PF08662.11 CBZ33287.1 - 1.2e-12 48.2 0.0 3.1e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A SH3_1 PF00018.28 CBZ33288.1 - 0.084 12.5 0.5 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 SH3 domain Methyltransf_32 PF13679.6 CBZ33289.1 - 3.8e-13 49.7 4.1 7.6e-07 29.2 0.3 3.0 2 1 1 3 3 3 2 Methyltransferase domain ubiquitin PF00240.23 CBZ33291.1 - 0.029 14.1 0.2 0.086 12.6 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin family Ribosomal_L25p PF01386.19 CBZ33292.1 - 0.16 12.5 0.0 0.32 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L25p family CTP_transf_like PF01467.26 CBZ33293.1 - 5.3e-19 68.8 0.0 7e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like Cyt-b5 PF00173.28 CBZ33294.1 - 5.7e-14 52.0 0.0 8.5e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3357 PF11837.8 CBZ33294.1 - 0.13 12.7 0.1 0.22 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) ALO PF04030.14 CBZ33295.1 - 1.1e-60 205.6 1.1 2.9e-56 191.2 0.2 2.1 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CBZ33295.1 - 4.8e-23 81.4 0.4 7.7e-23 80.8 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain SDA1 PF05285.12 CBZ33296.1 - 6.1e-76 256.1 65.8 7.7e-43 147.2 4.7 2.8 2 1 1 3 3 3 2 SDA1 NUC130_3NT PF08158.12 CBZ33296.1 - 5.1e-13 49.1 0.1 1.8e-12 47.4 0.1 2.1 1 0 0 1 1 1 1 NUC130/3NT domain DUF1828 PF08861.10 CBZ33296.1 - 0.49 10.7 2.4 1.9 8.8 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function DUF1828 Inositol_P PF00459.25 CBZ33299.1 - 1.3e-52 179.0 0.2 1.5e-52 178.8 0.2 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_C65 PF10275.9 CBZ33300.1 - 5.7e-65 219.2 0.0 6.5e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 CBZ33300.1 - 5.3e-05 23.7 0.0 0.0058 17.1 0.0 2.6 2 1 1 3 3 3 2 OTU-like cysteine protease zf-ZPR1 PF03367.13 CBZ33301.1 - 1.1e-109 363.4 0.0 7.1e-55 185.2 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DUF2387 PF09526.10 CBZ33301.1 - 0.044 13.9 4.0 1.1 9.4 0.1 2.9 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Pro_racemase PF05544.11 CBZ33301.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Proline racemase HypA PF01155.19 CBZ33301.1 - 0.12 12.4 6.1 1.1 9.3 0.5 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RRPl_C4 PF17026.5 CBZ33301.1 - 1.2 9.3 9.4 0.17 12.0 0.4 2.9 2 1 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc-ribbons_6 PF07191.12 CBZ33301.1 - 1.3 9.1 6.3 5.3 7.1 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbons FAM76 PF16046.5 CBZ33302.1 - 1.5 8.1 15.3 2.7 7.2 13.2 1.9 1 1 1 2 2 2 0 FAM76 protein MFS_1 PF07690.16 CBZ33303.1 - 3.2e-20 72.4 35.1 3.2e-20 72.4 35.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ion_trans PF00520.31 CBZ33304.1 - 1.9e-62 210.7 55.6 5.9e-24 84.6 8.4 4.1 4 0 0 4 4 4 4 Ion transport protein DUF3096 PF11295.8 CBZ33304.1 - 5 6.9 8.9 21 4.9 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) RabGAP-TBC PF00566.18 CBZ33305.1 - 1.2e-15 57.7 0.2 2.9e-15 56.5 0.2 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ferrochelatase PF00762.19 CBZ33306.1 - 2e-68 230.9 0.1 2.8e-53 181.0 0.0 2.0 2 0 0 2 2 2 2 Ferrochelatase CBP_BcsG PF11658.8 CBZ33307.1 - 0.14 10.6 0.1 0.39 9.1 0.0 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsG Arg_tRNA_synt_N PF03485.16 CBZ33307.1 - 0.49 11.0 3.3 1.8 9.2 0.1 2.5 1 1 1 2 2 2 0 Arginyl tRNA synthetase N terminal domain FoP_duplication PF13865.6 CBZ33307.1 - 0.63 10.6 1.8 3.6 8.2 1.4 2.2 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 PPR_2 PF13041.6 CBZ33308.1 - 4.1e-48 161.4 13.5 1.3e-07 31.7 0.0 13.6 10 3 6 16 16 16 9 PPR repeat family PPR PF01535.20 CBZ33308.1 - 2.1e-41 137.3 23.3 0.0005 20.1 0.1 18.2 19 0 0 19 19 19 11 PPR repeat PPR_3 PF13812.6 CBZ33308.1 - 2.5e-24 85.1 0.2 5.2e-05 23.2 0.0 8.6 7 1 1 8 8 8 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 CBZ33308.1 - 1.3e-16 60.0 6.2 0.071 12.8 0.0 12.0 13 0 0 13 13 13 4 PPR repeat PPR_long PF17177.4 CBZ33308.1 - 1.5e-12 47.4 0.6 0.0068 15.8 0.1 5.4 1 1 2 5 5 5 3 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 CBZ33308.1 - 8.7e-05 23.0 1.2 6.7 7.8 0.1 5.7 3 1 1 4 4 4 1 Tetratricopeptide repeat SPOB_a PF14689.6 CBZ33308.1 - 0.0081 15.9 1.5 23 4.8 0.0 5.6 7 0 0 7 7 7 0 Sensor_kinase_SpoOB-type, alpha-helical domain RNA_pol_Rpb4 PF03874.16 CBZ33308.1 - 0.083 13.2 0.0 6.6 7.1 0.0 3.7 4 1 1 5 5 5 0 RNA polymerase Rpb4 TPR_19 PF14559.6 CBZ33308.1 - 0.48 11.0 5.4 66 4.1 0.3 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat MDD_C PF18376.1 CBZ33309.1 - 2.3e-52 177.5 0.0 3.7e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CBZ33309.1 - 3.9e-06 27.0 3.9 8.7e-06 25.9 3.9 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain VirE2 PF07229.12 CBZ33309.1 - 0.14 10.8 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 VirE2 RRM_1 PF00076.22 CBZ33310.1 - 1.7e-06 27.8 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ33310.1 - 0.041 13.9 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif MFS_1 PF07690.16 CBZ33311.1 - 3.3e-22 78.9 45.6 3.3e-22 78.9 45.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ33311.1 - 7.9e-10 38.2 11.2 7.9e-10 38.2 11.2 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 CBZ33311.1 - 2.6e-09 35.9 26.4 0.0002 19.8 3.4 3.6 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 CBZ33311.1 - 1.4e-08 34.5 13.1 1.4e-08 34.5 13.1 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB zf-C2HC_2 PF13913.6 CBZ33314.1 - 4.2e-40 134.9 57.5 2.3e-09 36.9 2.2 8.4 9 0 0 9 9 8 6 zinc-finger of a C2HC-type DZR PF12773.7 CBZ33314.1 - 1.7e-16 60.0 53.6 4.8e-12 45.7 10.3 8.6 7 2 0 7 7 7 3 Double zinc ribbon zinc_ribbon_2 PF13240.6 CBZ33314.1 - 9.5e-06 25.2 58.4 0.0021 17.7 4.6 9.1 8 1 1 9 9 9 4 zinc-ribbon domain zf-ribbon_3 PF13248.6 CBZ33314.1 - 1.2e-05 24.5 59.3 0.00074 18.8 1.0 9.7 10 0 0 10 10 10 4 zinc-ribbon domain zinc_ribbon_15 PF17032.5 CBZ33314.1 - 0.0001 23.0 40.3 0.25 12.1 1.4 7.8 8 1 0 8 8 8 4 zinc-ribbon family NOB1_Zn_bind PF08772.11 CBZ33314.1 - 0.00043 20.4 0.3 0.00043 20.4 0.3 6.4 6 1 1 7 7 7 3 Nin one binding (NOB1) Zn-ribbon like UPF0547 PF10571.9 CBZ33314.1 - 0.00067 19.7 4.6 0.00067 19.7 4.6 9.4 9 1 0 9 9 9 1 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.12 CBZ33314.1 - 0.0086 16.0 2.8 0.0086 16.0 2.8 8.4 10 0 0 10 10 10 2 zinc-ribbons OTT_1508_deam PF14441.6 CBZ33314.1 - 0.076 13.0 2.9 11 6.2 0.2 2.9 2 0 0 2 2 2 0 OTT_1508-like deaminase c-SKI_SMAD_bind PF08782.10 CBZ33314.1 - 0.12 12.6 12.8 6.6 7.0 0.0 6.0 5 1 1 6 6 6 0 c-SKI Smad4 binding domain zf-CpG_bind_C PF12269.8 CBZ33314.1 - 0.27 11.0 16.4 8.8 6.0 0.0 6.0 7 0 0 7 7 7 0 CpG binding protein zinc finger C terminal domain zf_UBZ PF18439.1 CBZ33314.1 - 1.1 8.9 43.0 2 8.0 0.3 11.6 9 2 3 12 12 12 0 Ubiquitin-Binding Zinc Finger Rad50_zn_hook PF04423.14 CBZ33314.1 - 3 7.8 25.1 1 9.3 0.3 6.3 7 0 0 7 7 6 0 Rad50 zinc hook motif 3Beta_HSD PF01073.19 CBZ33315.1 - 1.8e-09 37.1 0.0 2.5e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CBZ33315.1 - 2.3e-06 27.6 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CBZ33315.1 - 7.1e-05 23.2 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 CBZ33315.1 - 8.1e-05 22.2 0.0 0.00019 21.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CBZ33315.1 - 0.00056 19.1 0.0 0.19 10.8 0.0 3.0 2 1 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.13 CBZ33315.1 - 0.0055 16.3 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 CBZ33315.1 - 0.048 13.8 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 CBZ33315.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 KR domain Glyco_hydro_31 PF01055.26 CBZ33316.1 - 1.4e-141 472.7 3.2 1.7e-141 472.4 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CBZ33316.1 - 2e-17 63.2 0.2 3e-16 59.5 0.1 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 CBZ33316.1 - 1e-06 28.9 0.2 2.4e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Arg_decarbox_C PF17944.1 CBZ33317.1 - 0.15 12.6 0.3 0.48 11.0 0.1 2.0 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension DUF726 PF05277.12 CBZ33318.1 - 1.1e-53 182.3 27.4 6.2e-52 176.6 0.0 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF726) VirJ PF06057.11 CBZ33318.1 - 0.043 13.7 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) MHC2-interact PF09307.10 CBZ33318.1 - 0.1 12.6 0.2 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 CLIP, MHC2 interacting DUF21 PF01595.20 CBZ33320.1 - 6.8e-31 107.3 0.5 1.3e-30 106.5 0.5 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CBZ33320.1 - 1.2e-06 28.8 0.5 0.0027 18.1 0.0 3.5 3 0 0 3 3 3 1 CBS domain cNMP_binding PF00027.29 CBZ33320.1 - 0.0066 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF21 PF01595.20 CBZ33321.1 - 9.3e-39 132.9 1.3 3e-38 131.3 0.2 2.1 1 1 1 2 2 2 1 Cyclin M transmembrane N-terminal domain Metallophos PF00149.28 CBZ33322.1 - 5.1e-30 105.5 0.3 8e-30 104.9 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CBZ33322.1 - 1.2e-21 76.8 0.5 6.1e-21 74.5 0.1 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 CBZ33322.1 - 4.6e-17 61.0 2.4 8.7e-05 22.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ33322.1 - 4.1e-14 51.5 4.0 0.00038 20.3 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ33322.1 - 7.8e-10 38.2 1.6 0.031 14.5 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ33322.1 - 2.2e-09 36.8 1.1 3.6e-05 23.3 0.1 2.9 2 1 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 CBZ33322.1 - 8.6e-06 26.3 1.7 0.0082 16.8 0.1 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ33322.1 - 2.1e-05 24.6 0.2 0.0004 20.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ33322.1 - 2.9e-05 24.5 1.3 0.032 15.1 0.1 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ33322.1 - 0.00032 21.1 1.4 0.0025 18.3 0.5 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ33322.1 - 0.014 15.7 2.3 4.1 7.8 0.6 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ33322.1 - 0.021 14.9 0.1 1.4 9.1 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ33322.1 - 0.027 14.5 0.1 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Lipase_3 PF01764.25 CBZ33323.1 - 1.2e-11 44.7 0.0 2.3e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CBZ33323.1 - 0.00016 22.4 0.1 0.00056 20.6 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Totivirus_coat PF05518.11 CBZ33323.1 - 0.12 10.4 0.0 0.19 9.7 0.0 1.2 1 0 0 1 1 1 0 Totivirus coat protein RRM_1 PF00076.22 CBZ33324.1 - 2.5e-28 97.7 0.0 2.3e-17 62.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ33324.1 - 0.00053 20.0 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CBZ33324.1 - 0.014 15.4 0.0 4.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CBZ33324.1 - 0.024 14.2 0.0 0.25 10.9 0.0 2.1 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBZ33324.1 - 0.093 12.8 0.0 0.39 10.8 0.0 2.1 2 1 0 2 2 2 0 Limkain b1 RRM_1 PF00076.22 CBZ33325.1 - 2.4e-18 65.7 0.0 3.7e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBZ33325.1 - 0.023 14.8 0.0 0.053 13.6 0.0 1.7 1 1 0 1 1 1 0 Limkain b1 RRM_5 PF13893.6 CBZ33325.1 - 0.034 13.7 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 CBZ33325.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Calcipressin RRM_7 PF16367.5 CBZ33325.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.7 2 1 0 2 2 2 0 RNA recognition motif RRM_1 PF00076.22 CBZ33326.1 - 2.2e-30 104.3 0.0 5.1e-18 64.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ33326.1 - 8e-05 22.6 0.0 0.097 12.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBZ33326.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif SET_assoc PF11767.8 CBZ33326.1 - 0.11 12.2 0.0 0.93 9.2 0.0 2.2 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Amino_oxidase PF01593.24 CBZ33327.1 - 1.3e-07 31.3 0.2 8.8e-07 28.6 0.2 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CBZ33327.1 - 3e-07 30.6 1.1 1.6e-06 28.2 0.3 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBZ33327.1 - 0.0055 16.0 0.1 0.014 14.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CBZ33327.1 - 0.026 14.5 0.2 0.084 12.9 0.2 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CBZ33327.1 - 0.037 13.3 0.5 0.058 12.6 0.5 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBZ33327.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CBZ33327.1 - 0.15 11.3 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 CBZ33327.1 - 0.15 10.7 0.3 0.25 10.0 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Aha1_N PF09229.11 CBZ33328.1 - 3.7e-26 92.0 0.4 5.1e-26 91.5 0.4 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CBZ33328.1 - 7.6e-19 68.2 0.0 2.9e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein DUF1180 PF06679.12 CBZ33328.1 - 0.63 10.4 2.2 0.97 9.8 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RRM_1 PF00076.22 CBZ33329.1 - 9.8e-12 44.5 0.0 1.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metal_resist PF13801.6 CBZ33329.1 - 0.077 13.2 1.8 2.8 8.1 0.2 2.7 2 0 0 2 2 2 0 Heavy-metal resistance ACC_epsilon PF13822.6 CBZ33331.1 - 0.8 10.4 0.1 0.8 10.4 0.1 3.7 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit Pkinase PF00069.25 CBZ33334.1 - 3.3e-58 197.1 0.0 4.3e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33334.1 - 3.4e-23 82.3 0.0 5.6e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ33334.1 - 0.0036 17.3 0.3 0.012 15.6 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBZ33334.1 - 0.0037 16.9 0.1 0.0071 16.0 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 CBZ33334.1 - 0.045 13.1 0.1 0.12 11.7 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UDPGT PF00201.18 CBZ33334.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Vir_act_alpha_C PF10400.9 CBZ33335.1 - 0.098 13.4 3.2 3.3 8.5 0.7 2.8 2 0 0 2 2 2 0 Virulence activator alpha C-term DnaB_bind PF10410.9 CBZ33335.1 - 0.22 11.7 2.2 4.6 7.5 0.1 3.1 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase DUF4404 PF14357.6 CBZ33335.1 - 0.52 11.0 4.0 0.67 10.6 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1484 PF07363.11 CBZ33335.1 - 0.63 11.1 0.1 0.63 11.1 0.1 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF1484) KfrA_N PF11740.8 CBZ33335.1 - 3.9 8.2 14.3 2.3 8.9 0.5 2.9 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term CoaE PF01121.20 CBZ33336.1 - 3.7e-21 75.6 0.7 2.3e-06 27.4 0.4 4.1 4 0 0 4 4 4 4 Dephospho-CoA kinase NTF2 PF02136.20 CBZ33337.1 - 4.9e-05 23.9 0.0 7.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 CBZ33337.1 - 0.097 12.5 0.0 0.35 10.7 0.0 1.9 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4379 PF14311.6 CBZ33339.1 - 6.8e-18 64.8 8.9 1.2e-08 35.2 1.5 3.0 2 1 0 2 2 2 2 Probable Zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CBZ33339.1 - 0.00096 19.1 7.5 0.12 12.4 2.4 3.5 3 0 0 3 3 3 1 Transposase zinc-ribbon domain DUF5313 PF17240.2 CBZ33339.1 - 0.022 15.2 0.1 0.043 14.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Elf1 PF05129.13 CBZ33339.1 - 0.039 14.0 2.3 3.7 7.7 0.2 3.0 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-ZPR1 PF03367.13 CBZ33339.1 - 0.089 12.6 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 ZPR1 zinc-finger domain zf-NADH-PPase PF09297.11 CBZ33339.1 - 0.12 12.0 0.6 0.12 12.0 0.6 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_10 PF10058.9 CBZ33339.1 - 0.29 10.9 3.8 25 4.7 0.5 3.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-HC5HC2H PF13771.6 CBZ33339.1 - 0.46 10.8 5.8 2.1 8.6 0.6 2.9 2 1 0 3 3 3 0 PHD-like zinc-binding domain Ima1_N PF09779.9 CBZ33339.1 - 0.95 10.3 6.4 7.1 7.5 2.6 2.5 3 0 0 3 3 3 0 Ima1 N-terminal domain VATC PF18716.1 CBZ33339.1 - 0.99 9.3 8.9 2.2 8.2 0.5 3.3 2 1 1 3 3 3 0 Vms1-associating treble clef domain DUF4187 PF13821.6 CBZ33339.1 - 1.4 8.7 6.4 8.9 6.2 2.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4187) Fer4_9 PF13187.6 CBZ33339.1 - 5 7.4 6.6 36 4.6 0.8 3.1 2 1 1 3 3 3 0 4Fe-4S dicluster domain Rubredoxin_2 PF18073.1 CBZ33339.1 - 5.7 6.8 14.4 4.1 7.2 0.4 3.4 3 0 0 3 3 3 0 Rubredoxin metal binding domain Zn-ribbon_8 PF09723.10 CBZ33339.1 - 9.7 6.4 8.4 60 3.9 3.0 3.1 2 1 0 2 2 2 0 Zinc ribbon domain DnaJ PF00226.31 CBZ33340.1 - 4.2e-15 55.6 0.0 7.6e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF446 PF04287.12 CBZ33340.1 - 0.052 13.6 0.1 0.095 12.8 0.1 1.4 1 0 0 1 1 1 0 tRNA pseudouridine synthase C DUF2615 PF11027.8 CBZ33340.1 - 0.17 12.0 0.1 0.3 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF535 PF04393.13 CBZ33340.1 - 0.31 10.3 0.7 0.44 9.7 0.2 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF535) FAM221 PF14753.6 CBZ33341.1 - 1.7e-14 53.8 18.9 6e-13 48.8 2.1 3.5 4 0 0 4 4 4 3 Protein FAM221A/B NOB1_Zn_bind PF08772.11 CBZ33341.1 - 0.018 15.2 1.5 0.018 15.2 1.5 2.9 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like DUF2616 PF11077.8 CBZ33341.1 - 0.2 11.3 3.8 0.37 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2616) ATP12 PF07542.11 CBZ33342.1 - 1.3e-19 70.6 0.0 3.5e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 ATP12 chaperone protein Peptidase_C13 PF01650.18 CBZ33343.1 - 1.3e-38 133.0 1.0 1.3e-38 133.0 0.1 1.4 2 0 0 2 2 2 1 Peptidase C13 family TTL PF03133.15 CBZ33344.1 - 5.1e-76 255.6 0.0 7.3e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ33344.1 - 3.8e-05 23.1 0.0 0.0016 17.8 0.0 2.8 3 0 0 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBZ33344.1 - 0.007 15.7 0.0 0.029 13.6 0.0 1.9 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF3884 PF13024.6 CBZ33344.1 - 0.1 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3884) Nuc_sug_transp PF04142.15 CBZ33347.1 - 1.2e-70 238.2 13.7 2.7e-63 214.0 5.8 2.5 2 1 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 CBZ33347.1 - 5.6e-06 26.6 4.3 5.6e-06 26.6 4.3 3.5 2 1 0 2 2 2 1 EamA-like transporter family PUNUT PF16913.5 CBZ33347.1 - 6.6e-05 22.3 5.4 0.0015 17.8 1.0 3.4 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport UAA PF08449.11 CBZ33347.1 - 0.0051 16.1 0.8 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.16 CBZ33347.1 - 0.025 13.9 0.3 0.025 13.9 0.3 2.8 3 0 0 3 3 3 0 Triose-phosphate Transporter family OGFr_III PF04680.13 CBZ33348.1 - 5.1 7.9 8.2 0.71 10.6 3.5 2.1 2 0 0 2 2 2 0 Opioid growth factor receptor repeat PAP2 PF01569.21 CBZ33350.1 - 5.5e-23 81.2 2.4 5.5e-23 81.2 2.4 1.9 3 0 0 3 3 3 1 PAP2 superfamily DUF2069 PF09842.9 CBZ33350.1 - 0.63 10.3 5.8 1.4 9.1 1.7 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) PAP2 PF01569.21 CBZ33351.1 - 2.9e-23 82.1 3.5 2.9e-23 82.1 3.5 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CBZ33351.1 - 0.0024 17.6 4.2 0.0024 17.6 4.2 2.6 2 1 0 2 2 2 1 PAP2 superfamily Peptidase_S10 PF00450.22 CBZ33352.1 - 6.3e-110 368.4 0.3 7.7e-110 368.2 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 CBZ33352.1 - 0.006 15.9 0.1 0.097 11.9 0.2 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ubiquitin_2 PF14560.6 CBZ33353.1 - 6.8e-23 80.9 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 CBZ33353.1 - 1.8e-19 69.5 0.2 2.9e-19 68.8 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 CBZ33353.1 - 0.03 14.1 0.0 0.27 11.0 0.0 2.2 1 1 0 1 1 1 0 Ubiquitin family WD40 PF00400.32 CBZ33354.1 - 2.3e-36 123.2 22.1 1.1e-06 29.3 1.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ33354.1 - 3.2e-11 43.4 3.1 0.036 14.4 0.1 5.6 2 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ33354.1 - 0.0048 15.6 0.6 0.59 8.7 0.5 2.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Pertus-S4-tox PF09275.10 CBZ33354.1 - 0.067 13.5 0.1 0.6 10.4 0.0 2.2 2 0 0 2 2 2 0 Pertussis toxin S4 subunit PALB2_WD40 PF16756.5 CBZ33354.1 - 0.1 11.5 7.2 1.1 8.1 0.4 2.8 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain CENP-F_leu_zip PF10473.9 CBZ33354.1 - 0.28 11.2 17.9 0.43 10.6 17.9 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 CBZ33354.1 - 1.6 9.3 15.9 1.1 9.7 0.9 2.5 2 1 0 2 2 2 0 Cell division protein ZapB UDG PF03167.19 CBZ33355.1 - 2.8e-18 66.4 0.0 4.5e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily BTB_2 PF02214.22 CBZ33356.1 - 9.2e-14 51.6 0.0 1.4e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Phage_CI_C PF16452.5 CBZ33356.1 - 0.15 12.4 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage CI repressor C-terminal domain PPR_3 PF13812.6 CBZ33357.1 - 0.00013 22.0 0.0 0.14 12.2 0.0 2.8 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 CBZ33357.1 - 0.073 13.3 0.0 3.5 7.9 0.0 3.0 3 0 0 3 3 3 0 PPR repeat family Aconitase PF00330.20 CBZ33358.1 - 2.8e-181 603.5 0.0 3.7e-181 603.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CBZ33358.1 - 1.7e-41 141.6 0.0 3.8e-41 140.5 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Lectin_N PF03954.14 CBZ33359.1 - 0.86 9.4 10.6 0.26 11.0 0.2 3.5 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain GIT_CC PF16559.5 CBZ33359.1 - 1.6 8.7 6.2 8.2 6.4 0.7 2.7 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor UPF0242 PF06785.11 CBZ33359.1 - 2.4 8.2 18.2 11 6.1 1.0 2.8 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LemA PF04011.12 CBZ33359.1 - 9 6.1 14.6 0.056 13.3 4.7 2.1 2 0 0 2 2 2 0 LemA family TBCC PF07986.12 CBZ33360.1 - 8.4e-34 115.9 0.1 1.3e-33 115.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C FOP_dimer PF09398.10 CBZ33360.1 - 0.00028 21.1 0.0 0.00065 19.9 0.0 1.6 1 0 0 1 1 1 1 FOP N terminal dimerisation domain CAP_C PF08603.11 CBZ33360.1 - 0.025 14.2 0.1 0.046 13.4 0.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal LisH_2 PF16045.5 CBZ33360.1 - 0.081 12.0 0.2 0.19 10.8 0.2 1.7 1 0 0 1 1 1 0 LisH PPP4R2 PF09184.11 CBZ33360.1 - 1.2 8.6 6.3 2.5 7.6 6.3 1.5 1 0 0 1 1 1 0 PPP4R2 RNA_pol_Rpc4 PF05132.14 CBZ33360.1 - 4.3 7.7 5.7 0.94 9.9 1.2 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 SR-25 PF10500.9 CBZ33360.1 - 5.8 6.5 12.1 11 5.6 12.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Phi29_Phage_SSB PF17427.2 CBZ33362.1 - 0.15 12.2 0.9 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 Phage Single-stranded DNA-binding protein Atrophin-1 PF03154.15 CBZ33362.1 - 6.4 4.9 6.6 7.2 4.8 6.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family V-ATPase_C PF03223.15 CBZ33363.1 - 8.2e-85 285.4 1.1 1e-84 285.1 1.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C ASH PF15780.5 CBZ33364.1 - 2.6e-24 85.3 11.1 0.0098 16.1 0.0 8.6 7 2 0 7 7 7 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CBZ33364.1 - 1.7e-12 47.4 6.3 0.009 16.2 0.2 5.1 5 0 0 5 5 5 4 Flagellar-associated PapD-like DUF1573 PF07610.11 CBZ33364.1 - 1.8e-08 34.3 0.0 0.36 10.9 0.0 7.3 8 1 0 8 8 8 1 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 CBZ33364.1 - 8.7e-06 25.9 1.1 1.3 9.3 0.1 5.2 5 0 0 5 5 5 2 Transmembrane protein 131-like Motile_Sperm PF00635.26 CBZ33364.1 - 0.00011 22.0 0.4 0.071 13.0 0.0 4.7 6 0 0 6 6 6 1 MSP (Major sperm protein) domain PapD_N PF00345.20 CBZ33364.1 - 0.034 14.1 0.0 18 5.2 0.0 3.4 4 0 0 4 4 4 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Glyco_hydro_30C PF17189.4 CBZ33364.1 - 0.035 14.3 0.1 5.9 7.2 0.1 3.7 2 1 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain MYCBPAP PF14646.6 CBZ33364.1 - 0.073 12.0 0.9 0.22 10.4 0.0 2.3 3 0 0 3 3 3 0 MYCBP-associated protein family ECH_1 PF00378.20 CBZ33365.1 - 2.4e-35 122.0 0.4 1.1e-32 113.3 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ33365.1 - 2e-13 50.5 1.0 3.5e-12 46.5 0.2 2.1 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase RRM_1 PF00076.22 CBZ33366.1 - 6.4e-17 61.1 0.0 1.3e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ33366.1 - 0.016 14.8 0.0 0.049 13.2 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ33366.1 - 0.064 13.4 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif Nup35_RRM_2 PF14605.6 CBZ33366.1 - 0.16 12.0 0.0 0.71 9.9 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif FYVE PF01363.21 CBZ33368.1 - 2.5e-19 69.2 8.7 2.5e-19 69.2 8.7 4.7 3 2 0 3 3 3 1 FYVE zinc finger zf-RanBP PF00641.18 CBZ33368.1 - 2.3e-15 55.6 61.8 4.8e-07 29.0 1.0 6.7 7 0 0 7 7 7 5 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 CBZ33368.1 - 0.00017 20.9 40.1 0.0048 16.3 2.4 6.7 6 2 0 6 6 6 5 Vacuolar protein sorting 36 NZF-N zinc-finger domain DZR PF12773.7 CBZ33368.1 - 0.015 15.3 50.4 0.6 10.2 9.6 5.7 3 2 1 4 4 4 0 Double zinc ribbon Peptidase_M41 PF01434.18 CBZ33369.1 - 9.4e-46 156.1 2.4 1.4e-45 155.6 2.4 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBZ33369.1 - 1.8e-39 135.2 0.0 3.2e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ33369.1 - 1.4e-06 28.8 1.2 5.2e-06 27.0 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ33369.1 - 0.00037 20.8 0.5 0.018 15.3 0.1 3.0 1 1 2 3 3 3 1 AAA domain AAA_5 PF07728.14 CBZ33369.1 - 0.00093 19.2 0.5 0.0062 16.5 0.2 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBZ33369.1 - 0.0011 19.2 0.2 0.0056 16.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 CBZ33369.1 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CBZ33369.1 - 0.011 15.5 1.3 0.1 12.3 0.0 2.9 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CBZ33369.1 - 0.022 14.5 0.1 0.073 12.8 0.1 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CBZ33369.1 - 0.027 13.8 0.1 1.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_lid_3 PF17862.1 CBZ33369.1 - 0.032 14.0 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA+ lid domain Peptidase_M50B PF13398.6 CBZ33369.1 - 0.046 13.3 0.1 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like TIP49 PF06068.13 CBZ33369.1 - 0.057 12.6 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CBZ33369.1 - 0.059 13.1 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 CBZ33369.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CBZ33369.1 - 0.1 11.9 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 CBZ33369.1 - 0.1 11.9 0.1 0.27 10.5 0.1 1.6 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 CBZ33369.1 - 0.15 12.0 0.3 0.73 9.7 0.2 2.1 2 0 0 2 2 2 0 NACHT domain Pkinase PF00069.25 CBZ33371.1 - 2.9e-75 253.0 0.0 3.3e-75 252.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33371.1 - 2.6e-39 135.1 0.0 3.1e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ33371.1 - 8.9e-10 38.3 0.0 1.5e-09 37.6 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBZ33371.1 - 4.6e-07 29.1 0.0 1.4e-06 27.5 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CBZ33371.1 - 1.8e-05 24.8 0.1 0.12 12.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CBZ33371.1 - 0.0057 16.0 0.1 0.0094 15.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phosducin PF02114.16 CBZ33371.1 - 0.093 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Phosducin Seadorna_VP7 PF07387.11 CBZ33371.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Choline_kinase PF01633.20 CBZ33371.1 - 0.18 11.4 0.0 0.32 10.5 0.0 1.5 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF421 PF04239.12 CBZ33371.1 - 0.19 11.5 2.0 0.27 11.0 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF421) PA26 PF04636.13 CBZ33372.1 - 3.2e-33 115.3 2.2 1.7e-11 43.8 0.1 3.1 3 0 0 3 3 3 3 PA26 p53-induced protein (sestrin) HEAT PF02985.22 CBZ33373.1 - 2.5e-21 73.9 15.6 0.012 15.8 0.0 10.5 11 0 0 11 11 11 6 HEAT repeat HEAT_2 PF13646.6 CBZ33373.1 - 1.1e-14 54.6 19.3 0.0085 16.5 0.0 7.3 4 4 2 7 7 7 5 HEAT repeats HEAT_EZ PF13513.6 CBZ33373.1 - 0.00041 20.8 3.9 0.077 13.5 0.0 4.8 5 0 0 5 5 5 1 HEAT-like repeat Adaptin_N PF01602.20 CBZ33373.1 - 0.0017 17.0 0.2 2.8 6.4 0.1 3.5 3 1 0 5 5 5 2 Adaptin N terminal region CLASP_N PF12348.8 CBZ33373.1 - 0.021 14.4 0.0 19 4.7 0.0 3.4 2 1 2 4 4 4 0 CLASP N terminal DUF2063 PF09836.9 CBZ33373.1 - 0.052 13.8 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 Putative DNA-binding domain CW_binding_2 PF04122.12 CBZ33373.1 - 0.14 12.8 2.4 0.7 10.6 2.4 2.2 1 1 0 1 1 1 0 Putative cell wall binding repeat 2 WES_acyltransf PF03007.16 CBZ33375.1 - 0.054 13.3 0.0 0.063 13.0 0.0 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Citrate_synt PF00285.21 CBZ33376.1 - 8.4e-61 206.0 0.1 1.1e-60 205.7 0.1 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Cyclin_C PF02984.19 CBZ33376.1 - 0.14 12.3 0.2 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain AAA_16 PF13191.6 CBZ33378.1 - 0.011 16.1 0.2 0.011 16.1 0.2 3.1 4 0 0 4 4 4 0 AAA ATPase domain Seryl_tRNA_N PF02403.22 CBZ33378.1 - 0.084 13.1 0.3 0.18 12.0 0.3 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4239 PF14023.6 CBZ33378.1 - 4.1 7.1 5.9 0.7 9.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) Tctex-1 PF03645.13 CBZ33379.1 - 6.8e-17 61.6 0.1 1.4e-16 60.6 0.1 1.5 1 0 0 1 1 1 1 Tctex-1 family LAT PF15234.6 CBZ33379.1 - 2.4 7.8 10.3 3.5 7.3 10.3 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells DUF4512 PF14975.6 CBZ33379.1 - 4.5 8.1 4.7 18 6.2 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) GTP_EFTU PF00009.27 CBZ33380.1 - 8.6e-53 178.8 0.1 1.5e-52 177.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ33380.1 - 1.6e-19 70.2 0.0 2.8e-18 66.3 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ33380.1 - 7.1e-09 35.9 0.9 1.8e-08 34.7 0.9 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ33380.1 - 0.0049 16.9 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBZ33380.1 - 0.042 13.6 0.6 3 7.6 0.1 2.5 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation zf-C2H2_jaz PF12171.8 CBZ33382.1 - 1.3e-08 34.9 1.5 2.1e-08 34.2 1.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBZ33382.1 - 7.3e-07 29.4 0.6 1.2e-06 28.7 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBZ33382.1 - 0.0041 17.4 0.6 0.0055 17.0 0.6 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.12 CBZ33382.1 - 0.043 13.9 1.4 0.071 13.2 1.4 1.4 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2 PF00096.26 CBZ33382.1 - 0.056 13.9 0.4 0.11 13.0 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type PDZ_6 PF17820.1 CBZ33383.1 - 5e-06 26.3 0.0 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBZ33383.1 - 0.0068 16.7 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBZ33383.1 - 0.1 13.0 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 PDZ domain RNA_pol_Rpb5_C PF01191.19 CBZ33384.1 - 2.8e-29 100.8 0.1 5.4e-29 99.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CBZ33384.1 - 2.4e-23 82.5 0.0 5.1e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain DUF4892 PF16234.5 CBZ33384.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4892) RNA_pol_Rpb5_C PF01191.19 CBZ33385.1 - 1.6e-23 82.3 0.0 3e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CBZ33385.1 - 3.6e-08 33.9 0.0 0.00015 22.3 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb5, N-terminal domain Ribosomal_S8 PF00410.19 CBZ33386.1 - 9.6e-08 32.0 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S8 PhnG PF06754.12 CBZ33386.1 - 0.018 15.0 0.5 0.029 14.3 0.5 1.2 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG CDP-OH_P_transf PF01066.21 CBZ33387.1 - 2.5e-16 60.2 0.1 2.5e-16 60.2 0.1 3.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HEAT_EZ PF13513.6 CBZ33388.1 - 1.1e-05 25.8 15.4 0.039 14.5 1.0 8.3 9 0 0 9 9 9 2 HEAT-like repeat HEAT PF02985.22 CBZ33388.1 - 0.00014 21.8 9.5 0.072 13.4 0.1 8.2 8 0 0 8 8 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 CBZ33388.1 - 0.03 14.9 0.8 49 4.6 0.0 5.4 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region SBF2 PF12335.8 CBZ33388.1 - 0.036 13.7 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Myotubularin protein TFCD_C PF12612.8 CBZ33388.1 - 9.2 6.0 6.9 2.8 7.7 0.0 3.6 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal WD40 PF00400.32 CBZ33389.1 - 2.5e-22 78.7 17.0 6.4e-07 30.0 0.1 11.2 11 1 1 12 12 12 4 WD domain, G-beta repeat Utp12 PF04003.12 CBZ33389.1 - 3.9e-12 46.4 0.2 1.2e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CBZ33389.1 - 1.3e-10 41.4 0.0 0.072 13.4 0.0 7.0 6 1 1 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ33389.1 - 0.001 18.1 0.5 1.7 7.5 0.0 3.9 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 CBZ33389.1 - 0.003 16.7 1.1 0.19 10.8 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1513) Nup160 PF11715.8 CBZ33389.1 - 0.04 12.6 0.1 0.57 8.8 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PD40 PF07676.12 CBZ33389.1 - 0.14 12.1 1.4 29 4.8 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat EPF PF17181.4 CBZ33389.1 - 0.19 11.8 0.4 0.44 10.6 0.4 1.5 1 0 0 1 1 1 0 Epidermal patterning factor proteins 14-3-3 PF00244.20 CBZ33390.1 - 0.21 11.1 0.2 3.5 7.1 0.0 2.5 3 0 0 3 3 3 0 14-3-3 protein AreA_N PF07573.11 CBZ33390.1 - 0.85 10.3 6.8 0.39 11.4 0.1 4.1 3 0 0 3 3 3 0 Nitrogen regulatory protein AreA N terminus XAP5 PF04921.14 CBZ33393.1 - 0.5 10.1 3.0 0.84 9.4 3.0 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator Pro_isomerase PF00160.21 CBZ33394.1 - 7.2e-33 114.1 0.0 1.2e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.22 CBZ33395.1 - 5.1e-54 182.2 1.6 7e-53 178.5 1.6 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CBZ33395.1 - 4.4e-35 120.5 0.1 8.2e-35 119.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ33395.1 - 2e-12 46.9 0.0 2.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ33395.1 - 2.4e-07 30.3 0.0 3.2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ33395.1 - 3.6e-06 27.0 0.0 8e-06 25.9 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ33395.1 - 3.1e-05 23.6 0.6 0.00073 19.1 0.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ33395.1 - 0.0027 17.6 0.1 0.085 12.8 0.0 2.4 1 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CBZ33395.1 - 0.0029 18.0 0.1 0.004 17.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CBZ33395.1 - 0.0059 16.3 0.1 0.041 13.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CBZ33395.1 - 0.015 14.9 0.8 4.3 6.9 0.0 2.5 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CBZ33395.1 - 0.033 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 CBZ33395.1 - 0.039 14.2 0.0 0.066 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CBZ33395.1 - 0.042 13.6 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 CBZ33395.1 - 0.048 13.6 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CBZ33395.1 - 0.053 13.0 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 CBZ33395.1 - 0.07 13.1 0.0 0.094 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CBZ33395.1 - 0.078 13.4 0.0 0.32 11.4 0.0 2.0 1 1 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 CBZ33395.1 - 0.097 11.8 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.9 CBZ33395.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA PF00004.29 CBZ33395.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_trans_1_4 PF13692.6 CBZ33396.1 - 0.00036 21.0 0.0 0.002 18.6 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 PPR_2 PF13041.6 CBZ33397.1 - 0.0018 18.4 0.0 1.7 8.9 0.0 3.4 2 1 1 3 3 3 2 PPR repeat family PPR_3 PF13812.6 CBZ33397.1 - 0.0026 17.8 0.0 0.43 10.7 0.0 2.8 2 1 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 CBZ33397.1 - 0.14 12.4 0.1 20 5.7 0.0 3.6 4 0 0 4 4 4 0 PPR repeat ANAPC4_WD40 PF12894.7 CBZ33398.1 - 0.00018 21.7 0.7 5.7 7.3 0.0 4.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBZ33398.1 - 0.0019 19.0 19.7 0.34 11.9 1.8 6.1 7 1 0 7 7 7 3 WD domain, G-beta repeat PD40 PF07676.12 CBZ33398.1 - 0.0062 16.4 0.0 1.4 9.0 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Myosin_TH1 PF06017.13 CBZ33399.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding V_ATPase_I PF01496.19 CBZ33399.1 - 4.7 5.0 9.4 6.5 4.5 9.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.6 CBZ33399.1 - 9.6 5.5 20.4 0.65 9.3 13.6 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Nrap_D5 PF17406.2 CBZ33400.1 - 1e-29 103.4 0.0 2.3e-29 102.2 0.0 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D3 PF17404.2 CBZ33400.1 - 4.1e-16 59.5 0.1 1.3e-15 57.9 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D4 PF17405.2 CBZ33400.1 - 1.7e-14 53.7 0.0 3.8e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 CBZ33400.1 - 3.6e-05 23.6 0.0 0.00062 19.6 0.0 2.7 3 0 0 3 3 3 1 Nrap protein PAP/OAS-like domain Mannosyl_trans2 PF04188.13 CBZ33402.1 - 1e-33 117.3 23.3 1.9e-20 73.6 10.7 4.2 4 0 0 4 4 4 4 Mannosyltransferase (PIG-V) Cnl2_NKP2 PF09447.10 CBZ33403.1 - 3.4 7.9 6.5 13 6.0 0.2 2.9 2 1 0 2 2 2 0 Cnl2/NKP2 family protein Cwf_Cwc_15 PF04889.12 CBZ33404.1 - 0.0065 16.2 9.8 0.01 15.6 9.8 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Cupin_8 PF13621.6 CBZ33404.1 - 0.13 12.0 0.4 0.15 11.8 0.4 1.1 1 0 0 1 1 1 0 Cupin-like domain FUSC PF04632.12 CBZ33404.1 - 0.18 10.3 5.1 0.21 10.1 5.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 CBZ33404.1 - 0.35 10.2 13.6 0.53 9.6 13.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UDPGP PF01704.18 CBZ33405.1 - 9.3e-116 386.9 0.0 1.6e-115 386.1 0.0 1.3 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Mito_carr PF00153.27 CBZ33406.1 - 3.3e-18 65.4 4.7 3.3e-08 33.3 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Robl_LC7 PF03259.17 CBZ33407.1 - 9.9e-22 76.5 0.0 1.1e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CBZ33407.1 - 0.033 14.1 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 NikR_C PF08753.11 CBZ33407.1 - 0.12 12.6 0.1 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 NikR C terminal nickel binding domain Synaptobrevin PF00957.21 CBZ33408.1 - 0.034 13.9 2.4 0.088 12.6 2.4 1.6 1 0 0 1 1 1 0 Synaptobrevin EzrA PF06160.12 CBZ33408.1 - 0.6 8.2 13.1 0.025 12.8 4.7 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA SOCS_box PF07525.16 CBZ33409.1 - 0.058 13.8 2.7 0.11 12.8 2.7 1.5 1 0 0 1 1 1 0 SOCS box PhoD PF09423.10 CBZ33410.1 - 1.6e-09 37.3 1.1 9.3e-07 28.2 0.6 2.8 2 1 0 2 2 2 2 PhoD-like phosphatase Hydantoinase_B PF02538.14 CBZ33411.1 - 3.4e-196 652.7 1.5 5.1e-196 652.1 1.5 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CBZ33411.1 - 1.2e-93 313.6 0.5 1.2e-93 313.6 0.5 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CBZ33411.1 - 7.6e-52 175.6 0.6 3.1e-50 170.4 0.1 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region NDUF_B7 PF05676.13 CBZ33412.1 - 0.048 13.4 3.2 0.18 11.6 2.9 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Peptidase_C2 PF00648.21 CBZ33413.1 - 1e-18 67.4 0.0 4.5e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 Calpain family cysteine protease Vps16_C PF04840.12 CBZ33414.1 - 8.5e-25 87.5 0.1 1e-11 44.5 0.0 2.3 2 0 0 2 2 2 2 Vps16, C-terminal region Vps16_N PF04841.13 CBZ33414.1 - 8.4e-24 84.1 0.0 8.4e-23 80.8 0.0 2.4 1 1 0 1 1 1 1 Vps16, N-terminal region Pkinase PF00069.25 CBZ33415.1 - 9.1e-73 244.9 0.0 1.1e-72 244.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33415.1 - 1.6e-36 125.9 0.0 2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ33415.1 - 6.2e-07 29.0 0.0 7.9e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ33415.1 - 0.00051 18.9 0.0 0.0051 15.6 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CBZ33415.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ33415.1 - 0.07 12.1 0.1 0.098 11.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PDEase_I PF00233.19 CBZ33416.1 - 2.8e-78 262.9 0.1 2.8e-78 262.9 0.1 2.3 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Ank_2 PF12796.7 CBZ33417.1 - 1.6e-18 67.0 0.5 1.6e-10 41.4 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ33417.1 - 6.4e-18 63.0 0.2 2.9e-05 24.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CBZ33417.1 - 7.2e-18 64.4 1.2 3.7e-06 27.1 0.0 4.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBZ33417.1 - 3.4e-16 59.4 1.2 1e-10 41.9 0.2 3.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CBZ33417.1 - 2.8e-14 52.8 0.1 3.8e-05 23.9 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat RteC PF09357.10 CBZ33417.1 - 0.036 13.7 0.0 7.3 6.2 0.0 2.1 2 0 0 2 2 2 0 RteC protein ISET-FN3_linker PF16625.5 CBZ33417.1 - 0.097 13.2 0.7 0.22 12.1 0.7 1.5 1 0 0 1 1 1 0 Unstructured linking region I-set and fnIII on Brother of CDO Methyltr_RsmB-F PF01189.17 CBZ33418.1 - 7.4e-33 113.9 0.0 1.8e-32 112.6 0.0 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CBZ33418.1 - 0.00093 19.3 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-AN1 PF01428.16 CBZ33419.1 - 1.4e-16 60.3 30.9 2.9e-09 36.9 9.5 3.0 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CBZ33419.1 - 0.00019 21.7 22.6 0.0076 16.6 3.6 3.2 3 0 0 3 3 3 2 Tc5 transposase C-terminal domain IBR PF01485.21 CBZ33419.1 - 0.38 11.0 23.3 0.075 13.3 4.3 3.1 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain Ras PF00071.22 CBZ33420.1 - 1.1e-51 174.7 0.1 4.2e-51 172.8 0.1 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CBZ33420.1 - 4.7e-32 110.7 0.0 1.4e-30 106.0 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ33420.1 - 2e-11 43.6 0.0 4.9e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ33420.1 - 4.6e-05 22.9 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ33420.1 - 0.0056 16.7 0.0 0.021 14.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 CBZ33420.1 - 0.007 16.1 0.0 0.035 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBZ33420.1 - 0.014 15.3 0.2 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 CBZ33420.1 - 0.015 15.8 0.1 0.021 15.3 0.1 1.6 1 1 0 1 1 1 0 ABC transporter DUF1327 PF07041.11 CBZ33420.1 - 0.08 13.0 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) GTP_EFTU PF00009.27 CBZ33420.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CBZ33420.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain Phage_Arf PF17585.2 CBZ33421.1 - 2 8.4 7.3 77 3.3 0.0 4.5 4 0 0 4 4 4 0 Accessory recombination function protein APG6_N PF17675.1 CBZ33421.1 - 7.4 7.1 150.3 0.018 15.6 6.0 10.0 3 1 7 10 10 10 0 Apg6 coiled-coil region zf-C3HC4_3 PF13920.6 CBZ33422.1 - 2.7e-16 59.2 11.0 4.8e-16 58.3 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ33422.1 - 6.7e-07 29.5 12.7 1.4e-06 28.5 12.7 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ33422.1 - 8.4e-07 28.7 12.6 1.7e-06 27.8 12.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CBZ33422.1 - 0.0013 18.5 16.0 0.0024 17.7 16.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.6 CBZ33422.1 - 0.0028 17.3 0.8 0.0073 16.0 0.8 1.8 1 0 0 1 1 1 1 zinc-ribbon domain zf-RING_5 PF14634.6 CBZ33422.1 - 0.01 15.8 11.9 0.021 14.8 11.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-P11 PF03854.14 CBZ33422.1 - 0.29 10.8 10.1 0.7 9.6 10.1 1.7 1 1 0 1 1 1 0 P-11 zinc finger SOG2 PF10428.9 CBZ33422.1 - 0.66 9.1 7.4 0.83 8.8 7.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF1180 PF06679.12 CBZ33422.1 - 3 8.2 7.0 6.3 7.2 7.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) TPR_7 PF13176.6 CBZ33423.1 - 0.13 12.4 0.2 0.29 11.2 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Cmc1 PF08583.10 CBZ33424.1 - 0.0059 16.6 2.3 0.013 15.4 2.3 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NPV_P10 PF05531.12 CBZ33425.1 - 0.5 10.9 10.0 0.062 13.8 1.3 3.4 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Complex1_LYR PF05347.15 CBZ33427.1 - 8.2e-12 45.0 2.0 8.2e-12 45.0 2.0 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CBZ33427.1 - 0.018 15.8 2.2 0.019 15.7 0.6 1.9 2 0 0 2 2 2 0 Complex1_LYR-like tRNA_edit PF04073.15 CBZ33428.1 - 2.5e-18 66.3 0.1 4e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA_edit PF04073.15 CBZ33429.1 - 9.7e-23 80.6 0.1 1.5e-22 79.9 0.1 1.3 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain SET PF00856.28 CBZ33430.1 - 3.2e-10 40.7 0.0 6.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 SET domain PIH1 PF08190.12 CBZ33431.1 - 8.1e-20 70.9 0.0 4e-08 32.9 0.0 3.3 2 1 1 3 3 3 3 PIH1 N-terminal domain PIH1_CS PF18201.1 CBZ33431.1 - 2.2e-09 37.6 0.0 6e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 PIH1 CS-like domain MCRS_N PF13325.6 CBZ33432.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein Myb_DNA-binding PF00249.31 CBZ33432.1 - 0.021 15.0 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Mito_carr PF00153.27 CBZ33433.1 - 5.4e-21 74.3 6.9 8.8e-10 38.4 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CBZ33434.1 - 4.8e-33 113.0 5.6 4.6e-12 45.7 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CBZ33435.1 - 4.8e-33 113.0 5.6 4.6e-12 45.7 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Phytochelatin PF05023.14 CBZ33437.1 - 0.0027 17.0 0.0 5.7 6.1 0.0 3.5 3 0 0 3 3 3 3 Phytochelatin synthase CDP-OH_P_transf PF01066.21 CBZ33438.1 - 1.3e-22 80.3 0.2 1.3e-22 80.3 0.2 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CTP_transf_like PF01467.26 CBZ33438.1 - 1.2e-15 57.9 0.0 2.2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 CBZ33438.1 - 0.05 13.5 0.1 0.58 10.0 0.1 2.5 3 0 0 3 3 3 0 FAD synthetase zf-CCCH PF00642.24 CBZ33439.1 - 0.00014 21.7 9.9 0.13 12.2 0.1 2.7 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ33439.1 - 0.0019 18.2 12.3 0.039 14.0 0.1 2.9 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 CBZ33439.1 - 0.0049 17.5 0.9 0.11 13.2 0.0 2.6 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 CBZ33439.1 - 0.32 11.5 11.0 3.5 8.3 0.8 2.9 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CBZ33439.1 - 0.52 10.5 6.5 11 6.3 1.3 2.5 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 CBZ33439.1 - 2.4 8.1 13.5 5.7 6.9 0.2 2.9 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH PF00642.24 CBZ33440.1 - 0.00038 20.3 8.2 0.08 12.9 2.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ33440.1 - 0.0011 18.7 8.5 0.019 14.7 0.4 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger DUF1150 PF06620.11 CBZ33440.1 - 0.036 14.2 0.3 28 4.9 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1150) zf_CCCH_4 PF18345.1 CBZ33440.1 - 6.8 6.9 15.6 1.3 9.2 3.9 2.8 3 0 0 3 3 3 0 Zinc finger domain ATG16 PF08614.11 CBZ33441.1 - 0.0033 17.7 23.3 0.0033 17.7 23.3 6.5 2 1 4 6 6 6 3 Autophagy protein 16 (ATG16) HSP70 PF00012.20 CBZ33442.1 - 1.5e-108 363.6 5.5 2.4e-102 343.1 0.0 2.9 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CBZ33442.1 - 0.00088 18.2 0.0 0.0063 15.4 0.0 2.3 1 1 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 CBZ33442.1 - 0.0079 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain E1_dh PF00676.20 CBZ33443.1 - 8.8e-100 333.5 0.2 1e-99 333.3 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CBZ33443.1 - 0.0028 16.9 1.2 0.0047 16.2 0.1 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase NDUF_B4 PF07225.12 CBZ33444.1 - 0.0092 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) HTH_32 PF13565.6 CBZ33444.1 - 0.069 13.8 0.9 0.069 13.8 0.9 2.7 3 0 0 3 3 3 0 Homeodomain-like domain Ribosomal_L34e PF01199.18 CBZ33445.1 - 1.4e-10 41.4 2.6 1.4e-10 41.4 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L34e PUF PF00806.19 CBZ33447.1 - 2.4e-45 149.7 0.6 1.3e-05 24.6 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat PMSR PF01625.21 CBZ33447.1 - 0.089 13.0 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 Peptide methionine sulfoxide reductase DnaJ PF00226.31 CBZ33448.1 - 1.1e-19 70.2 0.1 2.6e-19 69.1 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain EF-hand_7 PF13499.6 CBZ33449.1 - 3.9e-11 43.2 2.1 5.7e-08 33.1 0.9 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ33449.1 - 5e-09 35.4 1.4 8.3e-05 22.2 0.1 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CBZ33449.1 - 1.8e-07 30.2 2.5 0.0025 17.2 0.1 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CBZ33449.1 - 0.00017 21.3 6.3 0.15 11.9 0.1 3.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ33449.1 - 0.02 14.4 0.2 0.02 14.4 0.2 3.3 4 0 0 4 4 4 0 EF hand DUF3648 PF12364.8 CBZ33450.1 - 4.3e-56 189.0 3.1 1.2e-55 187.6 3.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3648) WD40 PF00400.32 CBZ33451.1 - 0.00031 21.5 4.8 0.088 13.7 0.2 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat NADH-G_4Fe-4S_3 PF10588.9 CBZ33453.1 - 1.4e-15 56.5 0.3 1.4e-15 56.5 0.3 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 CBZ33453.1 - 5e-12 45.7 1.4 5.9e-12 45.5 0.2 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 CBZ33453.1 - 9.1e-08 31.9 0.2 2.3e-07 30.7 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CBZ33453.1 - 0.099 13.3 6.5 0.22 12.1 3.1 2.9 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 CBZ33453.1 - 0.23 11.7 5.6 0.23 11.6 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain DnaJ PF00226.31 CBZ33454.1 - 1.4e-12 47.6 0.0 3.2e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 CBZ33454.1 - 6.6e-06 25.7 4.1 1.8e-05 24.3 4.1 1.7 1 1 0 1 1 1 1 CSL zinc finger E1-E2_ATPase PF00122.20 CBZ33458.1 - 1.6e-45 154.8 3.2 5.3e-45 153.1 0.3 3.1 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 CBZ33458.1 - 3.3e-17 63.5 0.0 8.5e-17 62.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CBZ33458.1 - 2.9e-13 49.3 0.0 6.4e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBZ33458.1 - 6e-05 22.9 0.0 0.00033 20.5 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ33458.1 - 0.009 16.1 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Kinesin PF00225.23 CBZ33459.1 - 2.3e-47 161.6 0.0 4.4e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ33459.1 - 3.6e-14 53.0 0.0 9.2e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding HlyE PF06109.13 CBZ33459.1 - 0.0052 16.1 0.6 0.0093 15.3 0.6 1.3 1 0 0 1 1 1 1 Haemolysin E (HlyE) AAA_16 PF13191.6 CBZ33459.1 - 0.0087 16.5 0.0 0.0087 16.5 0.0 4.0 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 CBZ33459.1 - 0.033 14.5 0.6 0.22 11.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBZ33459.1 - 0.086 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CBZ33459.1 - 0.099 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region UAA PF08449.11 CBZ33460.1 - 2.8e-47 161.4 9.2 1.3e-29 103.4 1.0 2.0 2 0 0 2 2 2 2 UAA transporter family CRT-like PF08627.10 CBZ33460.1 - 0.046 12.7 0.1 0.046 12.7 0.1 1.7 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like BTB PF00651.31 CBZ33461.1 - 0.0001 22.5 0.0 0.00035 20.8 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain MAD PF05557.13 CBZ33461.1 - 0.031 12.7 0.0 0.044 12.1 0.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein zf-C3HC4_3 PF13920.6 CBZ33463.1 - 2.4e-14 52.9 13.7 3.1e-14 52.5 13.7 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ33463.1 - 5.5e-06 26.1 14.0 8e-06 25.6 14.0 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBZ33463.1 - 0.00064 20.0 16.5 0.00094 19.5 16.5 1.3 1 0 0 1 1 1 1 Ring finger domain IU_nuc_hydro PF01156.19 CBZ33464.1 - 2.5e-92 309.7 2.4 2.8e-92 309.5 2.4 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Kinesin PF00225.23 CBZ33466.1 - 2.7e-62 210.6 0.1 5.4e-62 209.6 0.1 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ33466.1 - 2.6e-09 37.2 0.0 6.9e-09 35.8 0.0 1.7 1 1 0 1 1 1 1 Microtubule binding Noc2 PF03715.13 CBZ33467.1 - 2.5e-89 299.5 3.3 4.5e-89 298.6 3.3 1.4 1 0 0 1 1 1 1 Noc2p family YdjC PF04794.12 CBZ33467.1 - 0.046 13.7 1.1 0.3 11.0 0.1 2.4 2 0 0 2 2 2 0 YdjC-like protein PTPA PF03095.15 CBZ33467.1 - 0.091 12.2 2.3 9 5.6 0.1 2.7 3 0 0 3 3 3 0 Phosphotyrosyl phosphate activator (PTPA) protein DUF4375 PF14300.6 CBZ33467.1 - 1.1 9.5 4.1 3.4 7.9 4.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) Isy1 PF06246.12 CBZ33467.1 - 3.9 7.0 13.5 0.49 9.9 8.8 1.9 2 0 0 2 2 2 0 Isy1-like splicing family Got1 PF04178.12 CBZ33468.1 - 5e-12 46.2 15.3 6.2e-12 46.0 15.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family GlnE PF03710.15 CBZ33469.1 - 0.016 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase HCMVantigenic_N PF12154.8 CBZ33471.1 - 0.03 14.4 0.1 0.14 12.3 0.1 2.0 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV DnaJ PF00226.31 CBZ33472.1 - 8.6e-14 51.4 0.1 5.6e-13 48.8 0.1 2.2 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 CBZ33472.1 - 0.00024 21.0 6.2 1.1 9.5 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ33472.1 - 0.0084 15.9 0.5 37 4.4 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ33472.1 - 0.098 13.0 17.6 0.2 12.0 3.4 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ33472.1 - 0.4 10.9 4.5 27 5.0 0.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ33472.1 - 3 8.6 15.1 0.093 13.4 1.4 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat GCS PF03074.16 CBZ33473.1 - 8.1e-140 466.3 0.0 1.3e-139 465.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase Rx_N PF18052.1 CBZ33475.1 - 0.042 14.1 5.6 1.1 9.6 1.4 2.9 3 0 0 3 3 3 0 Rx N-terminal domain Peptidase_S49_N PF08496.10 CBZ33475.1 - 0.31 11.1 4.4 0.95 9.5 4.4 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Syntaxin-6_N PF09177.11 CBZ33475.1 - 0.48 11.0 5.6 0.4 11.3 2.1 2.4 2 2 0 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 CBZ33475.1 - 2.3 7.0 15.5 9.6 5.0 10.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Sec2p PF06428.11 CBZ33475.1 - 3.9 7.5 18.4 1.5 8.9 0.5 3.6 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 CBZ33475.1 - 7.1 6.8 10.5 2.5 8.3 4.1 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Histone PF00125.24 CBZ33477.1 - 1.2e-10 41.9 0.7 1.5e-10 41.5 0.7 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ33477.1 - 0.0021 18.3 0.3 0.0039 17.4 0.3 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GMP_synt_C PF00958.22 CBZ33477.1 - 0.13 12.3 1.3 0.18 11.9 0.8 1.5 1 1 0 1 1 1 0 GMP synthase C terminal domain SH3_9 PF14604.6 CBZ33478.1 - 1.7e-07 31.0 0.0 3.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBZ33478.1 - 8.7e-07 28.5 0.0 1.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBZ33478.1 - 0.0017 18.0 0.0 0.004 16.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF1772 PF08592.11 CBZ33478.1 - 0.041 14.2 0.0 0.081 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Connexin PF00029.19 CBZ33478.1 - 0.25 11.1 0.0 10 5.8 0.0 2.0 2 0 0 2 2 2 0 Connexin Auts2 PF15336.6 CBZ33478.1 - 6.4 6.8 9.7 0.33 11.0 3.0 2.1 2 1 1 3 3 3 0 Autism susceptibility gene 2 protein DnaJ PF00226.31 CBZ33479.1 - 2.4e-20 72.4 0.3 1.2e-19 70.2 0.3 2.3 1 0 0 1 1 1 1 DnaJ domain DUF865 PF05906.11 CBZ33479.1 - 0.18 11.7 0.5 0.33 10.8 0.5 1.4 1 0 0 1 1 1 0 Herpesvirus-7 repeat of unknown function (DUF865) HydF_tetramer PF18133.1 CBZ33480.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain DnaJ PF00226.31 CBZ33480.1 - 2.6 8.3 7.7 2.4 8.4 0.7 3.2 3 1 0 3 3 3 0 DnaJ domain Fibrillarin PF01269.17 CBZ33481.1 - 1.8e-99 331.5 0.0 2.1e-99 331.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CBZ33481.1 - 8.1e-07 29.0 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltr_RsmB-F PF01189.17 CBZ33481.1 - 0.004 16.8 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Lar_N PF09861.9 CBZ33481.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain FtsJ PF01728.19 CBZ33481.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Clathrin_lg_ch PF01086.17 CBZ33482.1 - 1.3e-07 31.9 1.4 1.8e-07 31.5 1.4 1.2 1 0 0 1 1 1 1 Clathrin light chain NUDE_C PF04880.13 CBZ33482.1 - 6.5 7.2 18.2 0.46 11.0 11.2 2.3 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region SNARE PF05739.19 CBZ33483.1 - 6.6e-09 35.6 0.8 1.4e-08 34.6 0.3 1.8 2 0 0 2 2 2 1 SNARE domain PspA_IM30 PF04012.12 CBZ33483.1 - 0.00029 20.5 0.6 0.00057 19.5 0.2 1.6 1 1 0 1 1 1 1 PspA/IM30 family Syntaxin_2 PF14523.6 CBZ33483.1 - 0.00061 20.1 4.0 0.036 14.4 0.1 2.3 2 0 0 2 2 2 2 Syntaxin-like protein ORC4_C PF14629.6 CBZ33483.1 - 0.0078 15.6 0.1 1.9 7.8 0.0 2.1 2 0 0 2 2 2 2 Origin recognition complex (ORC) subunit 4 C-terminus Vac_Fusion PF02346.16 CBZ33483.1 - 0.052 13.2 1.1 7.6 6.2 0.1 3.2 2 1 1 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 UPF0242 PF06785.11 CBZ33483.1 - 0.14 12.2 8.4 0.24 11.5 8.4 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Med9 PF07544.13 CBZ33483.1 - 0.21 11.7 5.5 2.2 8.4 0.5 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3584 PF12128.8 CBZ33483.1 - 0.87 7.0 12.5 1.1 6.7 12.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec2p PF06428.11 CBZ33483.1 - 1.2 9.1 7.1 0.31 11.0 0.2 2.5 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.19 CBZ33483.1 - 1.5 6.6 6.7 2.6 5.9 0.1 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 CBZ33483.1 - 1.7 7.5 11.7 0.41 9.5 3.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF745 PF05335.13 CBZ33483.1 - 4.3 7.0 8.4 5.6 6.6 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) FliJ PF02050.16 CBZ33483.1 - 9.7 6.4 14.9 2.8 8.2 3.2 2.8 2 1 0 2 2 2 0 Flagellar FliJ protein DER1 PF04511.15 CBZ33484.1 - 1.1e-32 113.5 7.7 1.3e-32 113.3 7.7 1.0 1 0 0 1 1 1 1 Der1-like family Phage_holin_3_2 PF04550.12 CBZ33484.1 - 0.34 11.5 2.2 5.8 7.5 0.1 3.0 3 0 0 3 3 3 0 Phage holin family 2 Pkinase PF00069.25 CBZ33485.1 - 2.2e-50 171.5 0.0 3.9e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33485.1 - 6.6e-25 87.9 0.0 5.3e-20 71.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.25 CBZ33485.1 - 3.2e-16 59.1 0.5 7.2e-16 58.0 0.5 1.6 1 0 0 1 1 1 1 CAP-Gly domain Kinase-like PF14531.6 CBZ33485.1 - 7.5e-05 22.2 0.0 0.031 13.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CBZ33485.1 - 0.98 9.3 4.1 0.54 10.1 0.2 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 CBZ33486.1 - 2.2e-57 194.4 0.0 2.5e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33486.1 - 7.9e-34 117.1 0.0 9.3e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ33486.1 - 2.6e-05 23.2 0.0 3.6e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 CBZ33486.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.7 2 0 0 2 2 2 1 ABC1 family Kinase-like PF14531.6 CBZ33486.1 - 0.19 11.0 0.0 0.28 10.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Peptidase_M24 PF00557.24 CBZ33487.1 - 1e-22 80.9 1.1 1.4e-22 80.4 1.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pkinase PF00069.25 CBZ33489.1 - 4.7e-72 242.5 0.0 5.6e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33489.1 - 1.4e-32 113.0 0.1 2.6e-31 108.8 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ33489.1 - 0.043 13.7 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MYO10_CC PF16735.5 CBZ33489.1 - 0.51 10.5 3.0 12 6.1 0.9 2.3 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain MBF1 PF08523.10 CBZ33490.1 - 2.7e-11 43.8 5.6 2.7e-11 43.8 5.6 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CBZ33490.1 - 5.8e-11 42.3 0.2 1e-10 41.5 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CBZ33490.1 - 0.0026 18.1 0.7 0.005 17.1 0.7 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 CBZ33490.1 - 0.0055 17.3 1.8 0.0094 16.5 0.3 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_19 PF12844.7 CBZ33490.1 - 0.012 15.6 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MqsA_antitoxin PF15731.5 CBZ33490.1 - 0.06 13.5 0.4 0.093 12.8 0.4 1.4 1 1 0 1 1 1 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA Mito_carr PF00153.27 CBZ33491.1 - 5.6e-18 64.6 0.0 6.5e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.27 CBZ33492.1 - 5.2e-67 221.8 4.9 1.2e-23 82.8 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CBZ33492.1 - 0.014 14.6 0.1 0.024 13.8 0.1 1.3 1 0 0 1 1 1 0 Fuseless polyprenyl_synt PF00348.17 CBZ33493.1 - 3.8e-51 173.6 0.0 5.2e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase CrtC PF07143.11 CBZ33493.1 - 2e-16 61.1 0.0 2.5e-15 57.5 0.0 2.2 1 1 0 1 1 1 1 CrtC N-terminal lipocalin domain Lipocalin_9 PF17186.4 CBZ33493.1 - 8.4e-11 42.3 0.0 1.5e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain Complex1_LYR PF05347.15 CBZ33494.1 - 1.6e-07 31.3 1.5 1.6e-06 28.1 0.0 3.4 4 0 0 4 4 4 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CBZ33494.1 - 0.0081 16.9 0.3 0.0081 16.9 0.3 2.9 3 1 1 4 4 4 1 Complex1_LYR-like DUF1192 PF06698.11 CBZ33494.1 - 0.12 12.4 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) GN3L_Grn1 PF08701.11 CBZ33495.1 - 9.2e-06 25.7 14.5 2.1e-05 24.5 14.5 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase DUF4337 PF14235.6 CBZ33495.1 - 0.72 9.9 4.1 1.9 8.6 4.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) UVR PF02151.19 CBZ33496.1 - 2.3e-09 36.7 14.9 7.5e-06 25.5 1.6 2.7 2 0 0 2 2 2 2 UvrB/uvrC motif zf-Di19 PF05605.12 CBZ33496.1 - 0.0081 16.4 4.5 0.0081 16.4 4.5 2.7 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 CBZ33496.1 - 0.088 13.3 0.1 0.088 13.3 0.1 3.6 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_4 PF13894.6 CBZ33496.1 - 0.73 10.8 16.4 0.26 12.2 0.6 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-RAG1 PF10426.9 CBZ33496.1 - 4.1 7.6 7.9 6.6 7.0 0.5 3.1 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain Kinesin PF00225.23 CBZ33497.1 - 1.2e-102 343.3 0.0 2.1e-102 342.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ33497.1 - 2.3e-45 154.2 0.0 7.5e-45 152.5 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding VHS PF00790.19 CBZ33497.1 - 1.9e-06 27.8 0.2 8.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 VHS domain Macoilin PF09726.9 CBZ33497.1 - 0.0088 14.7 4.4 0.014 14.0 4.4 1.2 1 0 0 1 1 1 1 Macoilin family DUF5600 PF18150.1 CBZ33499.1 - 7e-17 62.0 0.0 1.4e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) Dynamin_N PF00350.23 CBZ33499.1 - 2.2e-14 53.9 0.0 1.6e-12 47.8 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBZ33499.1 - 5.8e-07 29.6 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 CBZ33499.1 - 8.8e-05 22.3 0.2 0.00028 20.7 0.1 1.8 2 0 0 2 2 2 1 N-terminal EH-domain containing protein RsgA_GTPase PF03193.16 CBZ33499.1 - 0.11 12.4 0.0 12 5.8 0.0 2.9 3 0 0 3 3 3 0 RsgA GTPase AAA_25 PF13481.6 CBZ33499.1 - 0.13 11.8 0.0 0.37 10.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain GET2 PF08690.10 CBZ33499.1 - 4.1 7.0 5.6 6.6 6.3 5.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 U-box PF04564.15 CBZ33501.1 - 0.0033 17.6 0.0 0.011 15.9 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 CBZ33501.1 - 0.0091 16.1 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF1846 PF08903.11 CBZ33501.1 - 0.035 12.7 0.3 0.044 12.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) DUF2937 PF11157.8 CBZ33501.1 - 0.049 13.3 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) zf-C4H2 PF10146.9 CBZ33501.1 - 0.099 12.9 1.4 0.21 11.9 1.4 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein zf_CCCH_4 PF18345.1 CBZ33501.1 - 0.89 9.7 8.1 0.82 9.8 1.4 2.5 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 CBZ33502.1 - 6.8e-05 22.7 6.9 0.0038 17.1 1.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) U-box PF04564.15 CBZ33502.1 - 0.0078 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 CBZ33502.1 - 0.024 14.7 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf_CCCH_4 PF18345.1 CBZ33502.1 - 0.32 11.1 9.8 0.11 12.6 2.7 2.5 2 0 0 2 2 2 0 Zinc finger domain Menin PF05053.13 CBZ33502.1 - 3.6 5.8 9.0 4.9 5.4 9.0 1.1 1 0 0 1 1 1 0 Menin Sec8_exocyst PF04048.14 CBZ33502.1 - 8.8 6.2 6.8 3.6 7.5 0.1 2.8 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain UPF0016 PF01169.19 CBZ33503.1 - 2e-43 146.6 19.5 1.1e-22 80.2 3.5 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 AbrB PF05145.12 CBZ33503.1 - 0.0004 19.5 6.8 0.0025 16.8 6.8 1.8 1 1 0 1 1 1 1 Transition state regulatory protein AbrB Ion_trans PF00520.31 CBZ33503.1 - 0.0044 16.3 0.1 0.0052 16.0 0.1 1.3 1 1 0 1 1 1 1 Ion transport protein Abhydrolase_9_N PF15420.6 CBZ33503.1 - 0.025 14.6 4.1 0.038 14.0 0.1 2.2 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus MttA_Hcf106 PF02416.16 CBZ33503.1 - 0.52 9.7 3.1 8.3 5.8 0.1 2.4 2 0 0 2 2 2 0 mttA/Hcf106 family ABC_transp_aux PF09822.9 CBZ33504.1 - 1e-06 28.5 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF4350 PF14258.6 CBZ33504.1 - 0.0029 18.0 0.0 0.039 14.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4350) Coatomer_WDAD PF04053.14 CBZ33505.1 - 0.0043 16.1 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CBZ33505.1 - 0.017 15.9 0.1 0.017 15.9 0.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ33505.1 - 0.093 13.0 0.0 13 6.1 0.0 3.7 3 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1143 PF06608.11 CBZ33506.1 - 0.0013 18.8 0.4 0.76 9.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1143) Radical_SAM PF04055.21 CBZ33507.1 - 1.3e-10 41.9 0.2 2.2e-10 41.2 0.2 1.4 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 CBZ33507.1 - 4.5e-10 39.9 0.1 1.1e-09 38.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Pkinase PF00069.25 CBZ33508.1 - 2e-28 99.5 0.1 1.2e-15 57.6 0.0 4.0 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33508.1 - 2.3e-07 30.4 0.1 0.011 15.0 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 CBZ33508.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family PRCH PF03967.13 CBZ33508.1 - 0.085 13.1 1.2 0.33 11.2 1.2 2.0 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region WD40 PF00400.32 CBZ33510.1 - 1.5e-08 35.2 0.5 0.0082 17.0 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat PDZ_2 PF13180.6 CBZ33510.1 - 0.00032 21.0 0.0 0.0008 19.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 CBZ33510.1 - 0.0036 17.1 0.2 0.012 15.5 0.2 1.8 1 0 0 1 1 1 1 PDZ domain CHASE3 PF05227.13 CBZ33510.1 - 0.99 9.3 6.7 16 5.4 1.8 3.0 2 0 0 2 2 2 0 CHASE3 domain Synaptobrevin PF00957.21 CBZ33511.1 - 9.7e-12 44.5 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CBZ33511.1 - 0.031 14.3 0.0 0.088 12.9 0.0 1.7 2 0 0 2 2 2 0 Regulated-SNARE-like domain UMP1 PF05348.11 CBZ33512.1 - 4e-05 23.8 0.0 5e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 TFIIS_C PF01096.18 CBZ33513.1 - 3.2e-19 68.5 2.6 3.2e-19 68.5 2.6 2.6 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CBZ33513.1 - 7e-06 25.8 1.4 2.5e-05 24.0 0.2 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CBZ33513.1 - 0.002 18.1 2.3 0.22 11.5 0.2 2.6 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 CBZ33513.1 - 0.0091 15.6 0.4 0.02 14.6 0.0 1.7 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain GILT PF03227.16 CBZ33513.1 - 0.035 14.3 0.6 0.053 13.8 0.6 1.4 1 0 0 1 1 1 0 Gamma interferon inducible lysosomal thiol reductase (GILT) TF_Zn_Ribbon PF08271.12 CBZ33513.1 - 0.043 13.3 0.4 3.1 7.4 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zinc_ribbon_10 PF10058.9 CBZ33513.1 - 0.14 11.9 3.3 3.7 7.4 0.1 3.3 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein PhnA_Zn_Ribbon PF08274.12 CBZ33513.1 - 0.62 10.1 0.1 0.62 10.1 0.1 2.9 2 1 1 3 3 3 0 PhnA Zinc-Ribbon Elf1 PF05129.13 CBZ33513.1 - 0.95 9.6 4.3 9.4 6.4 0.2 2.5 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like NAP PF00956.18 CBZ33515.1 - 1.3e-58 198.3 0.6 1.3e-58 198.3 0.6 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DpnI_C PF17726.1 CBZ33515.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Dam-replacing HTH domain Cwf_Cwc_15 PF04889.12 CBZ33515.1 - 0.9 9.2 5.5 0.22 11.2 1.8 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 CBZ33515.1 - 0.99 7.4 8.0 2.1 6.3 8.0 1.5 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 CBZ33515.1 - 5.8 6.2 8.8 0.52 9.7 4.0 1.6 2 0 0 2 2 2 0 SDA1 PGA2 PF07543.12 CBZ33515.1 - 6.2 6.8 8.4 0.83 9.6 3.0 2.3 2 1 0 2 2 2 0 Protein trafficking PGA2 CCDC53 PF10152.9 CBZ33517.1 - 3.5e-45 154.1 0.0 4.7e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex YebO PF13974.6 CBZ33517.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 YebO-like protein UPF0193 PF05250.11 CBZ33521.1 - 0.00027 20.8 2.6 0.00046 20.0 2.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) ZapB PF06005.12 CBZ33521.1 - 0.23 11.9 2.0 4.2 7.9 0.1 2.9 3 0 0 3 3 3 0 Cell division protein ZapB PilJ PF13675.6 CBZ33521.1 - 0.88 9.6 5.1 0.83 9.7 1.4 2.5 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term LRR_4 PF12799.7 CBZ33524.1 - 0.0001 22.6 0.1 0.068 13.6 0.0 3.5 3 1 2 5 5 5 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ33524.1 - 0.0037 16.8 0.0 0.31 10.5 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CBZ33524.1 - 0.021 14.6 0.0 8.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Leucine rich repeat Peptidase_M24 PF00557.24 CBZ33525.1 - 1.1e-47 162.4 0.0 1.5e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CBZ33525.1 - 1.8e-14 53.8 7.3 3.5e-14 52.8 7.3 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CBZ33525.1 - 5e-06 26.5 4.4 1.2e-05 25.2 4.4 1.7 1 0 0 1 1 1 1 MYND finger CH_2 PF06294.11 CBZ33526.1 - 2.4e-16 59.6 0.0 6.5e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 CH-like domain in sperm protein DUF2189 PF09955.9 CBZ33527.1 - 2.7 8.2 7.8 20 5.4 7.8 1.9 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2189) TBCC PF07986.12 CBZ33529.1 - 3.1e-27 94.7 9.6 5.3e-09 35.8 0.0 3.5 3 0 0 3 3 3 3 Tubulin binding cofactor C CAP_C PF08603.11 CBZ33529.1 - 0.11 12.1 0.7 0.23 11.1 0.7 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal Pkinase PF00069.25 CBZ33530.1 - 4.6e-46 157.3 0.0 8.9e-36 123.6 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33530.1 - 1.6e-15 57.1 0.0 9.3e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DUF1908 PF08926.11 CBZ33531.1 - 1.2 8.1 3.7 2 7.4 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) DUF2508 PF10704.9 CBZ33531.1 - 6.4 7.0 5.2 1.2 9.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) DAG1 PF05454.11 CBZ33532.1 - 0.027 13.8 0.3 0.032 13.6 0.3 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Mid2 PF04478.12 CBZ33532.1 - 0.12 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor CYTH PF01928.21 CBZ33533.1 - 1e-13 51.6 0.0 0.00011 22.2 0.0 3.6 3 0 0 3 3 3 3 CYTH domain Histone PF00125.24 CBZ33534.1 - 2.2e-37 128.3 4.6 2.7e-37 128.1 4.6 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ33534.1 - 2.6e-06 27.6 0.0 5.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CBZ33534.1 - 5.3e-05 23.3 0.2 5.3e-05 23.3 0.2 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 CBZ33534.1 - 0.0047 17.0 0.0 0.0077 16.3 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CBZ33534.1 - 0.028 14.4 0.1 0.054 13.5 0.1 1.5 1 0 0 1 1 1 0 Bromodomain associated ORC4_C PF14629.6 CBZ33534.1 - 0.041 13.2 0.6 0.072 12.4 0.5 1.5 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus Gene66 PF02053.15 CBZ33534.1 - 0.044 13.4 1.2 0.051 13.2 1.2 1.2 1 0 0 1 1 1 0 Gene 66 (IR5) protein NUC PF18510.1 CBZ33534.1 - 0.094 13.2 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Nuclease domain ANF_receptor PF01094.28 CBZ33535.1 - 4.7e-34 118.0 6.3 1.2e-25 90.4 3.3 3.2 3 0 0 3 3 3 3 Receptor family ligand binding region Peripla_BP_6 PF13458.6 CBZ33535.1 - 0.0012 18.6 7.0 0.0029 17.3 1.1 2.7 2 1 0 2 2 2 2 Periplasmic binding protein Methyltransf_23 PF13489.6 CBZ33536.1 - 0.038 13.8 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_A_bac PF01000.26 CBZ33537.1 - 7.6e-20 71.4 0.0 1.2e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CBZ33537.1 - 2.2e-13 49.4 0.0 3.5e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 CBZ33537.1 - 0.014 15.5 0.4 0.032 14.4 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_10 PF13237.6 CBZ33537.1 - 0.024 14.7 0.8 0.057 13.5 0.8 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 CBZ33537.1 - 0.054 14.1 0.4 0.15 12.7 0.4 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain DUF5349 PF17298.2 CBZ33537.1 - 0.14 11.9 2.6 0.21 11.3 2.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Fer4_6 PF12837.7 CBZ33537.1 - 0.18 11.9 1.5 0.55 10.4 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain DUF2852 PF11014.8 CBZ33538.1 - 0.024 14.8 1.3 0.024 14.8 1.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) ACP_PD PF04336.12 CBZ33538.1 - 0.27 11.7 2.2 4.5 7.7 0.1 2.2 1 1 1 2 2 2 0 Acyl carrier protein phosphodiesterase Kinesin PF00225.23 CBZ33539.1 - 1.7e-06 27.2 0.1 3.9e-06 26.0 0.1 1.8 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ33539.1 - 0.18 11.7 0.0 1.1 9.2 0.0 2.0 2 0 0 2 2 2 0 Microtubule binding Kinesin PF00225.23 CBZ33540.1 - 2.2e-16 59.7 0.4 1.8e-15 56.7 0.2 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ33540.1 - 8e-11 42.1 0.3 7.4e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding Kinesin PF00225.23 CBZ33541.1 - 6.2e-94 314.6 2.7 5.4e-76 255.7 0.4 4.3 3 0 0 3 3 3 3 Kinesin motor domain Microtub_bd PF16796.5 CBZ33541.1 - 5.6e-16 58.8 0.0 1.3e-08 34.9 0.0 4.4 3 0 0 3 3 3 3 Microtubule binding Kinesin_assoc PF16183.5 CBZ33541.1 - 0.00083 19.6 1.8 0.00083 19.6 1.8 10.4 1 1 5 8 8 8 1 Kinesin-associated Ldh_1_N PF00056.23 CBZ33542.1 - 9.5e-36 123.0 0.6 1.4e-35 122.4 0.6 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBZ33542.1 - 9.5e-34 116.7 0.0 1.4e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CBZ33542.1 - 0.014 14.5 0.0 0.06 12.3 0.0 1.8 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 CBZ33542.1 - 0.083 12.3 0.2 0.15 11.5 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DUF1664 PF07889.12 CBZ33543.1 - 1.8e-07 31.2 11.2 0.0066 16.5 0.8 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CBZ33543.1 - 6.2e-06 26.3 7.6 0.028 14.5 0.4 3.3 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 CBZ33543.1 - 2.3e-05 23.4 11.1 0.015 14.2 0.4 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein Alanine_zipper PF11839.8 CBZ33543.1 - 0.00055 20.3 4.8 0.00055 20.3 4.8 3.3 3 0 0 3 3 3 1 Alanine-zipper, major outer membrane lipoprotein Mod_r PF07200.13 CBZ33543.1 - 0.00068 19.8 10.6 0.4 10.8 0.1 3.0 2 1 1 3 3 3 2 Modifier of rudimentary (Mod(r)) protein zf-C4H2 PF10146.9 CBZ33543.1 - 0.0011 19.3 4.7 0.21 11.9 1.9 2.2 2 0 0 2 2 2 2 Zinc finger-containing protein Bacillus_HBL PF05791.11 CBZ33543.1 - 0.0013 18.6 3.6 0.55 10.0 0.4 2.8 2 1 1 3 3 3 2 Bacillus haemolytic enterotoxin (HBL) Helo_like_N PF17111.5 CBZ33543.1 - 0.0019 17.6 8.7 0.0042 16.5 0.7 2.8 1 1 0 3 3 3 1 Fungal N-terminal domain of STAND proteins Syntaxin_2 PF14523.6 CBZ33543.1 - 0.015 15.7 10.4 0.17 12.3 0.6 3.7 1 1 0 2 2 2 0 Syntaxin-like protein Fez1 PF06818.15 CBZ33543.1 - 0.02 15.4 16.0 0.56 10.6 9.4 2.4 1 1 1 2 2 2 0 Fez1 LOH1CR12 PF10158.9 CBZ33543.1 - 0.031 14.3 3.6 0.16 12.0 0.1 2.9 2 1 1 3 3 3 0 Tumour suppressor protein BAR_3 PF16746.5 CBZ33543.1 - 0.034 13.9 4.1 0.18 11.5 0.0 2.6 2 1 0 2 2 2 0 BAR domain of APPL family CREPT PF16566.5 CBZ33543.1 - 0.041 14.1 11.4 1.1 9.4 0.8 3.3 1 1 2 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF948 PF06103.11 CBZ33543.1 - 0.041 14.1 9.3 11 6.3 0.1 4.2 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) AKNA PF12443.8 CBZ33543.1 - 0.042 14.5 1.0 0.13 12.9 0.1 2.3 2 1 0 2 2 1 0 AT-hook-containing transcription factor Fib_alpha PF08702.10 CBZ33543.1 - 0.049 13.8 9.0 0.84 9.8 1.3 3.3 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family IFT57 PF10498.9 CBZ33543.1 - 0.055 12.4 8.2 0.093 11.7 1.7 2.3 1 1 0 2 2 2 0 Intra-flagellar transport protein 57 Tropomyosin_1 PF12718.7 CBZ33543.1 - 0.057 13.6 17.8 0.65 10.1 10.1 3.1 1 1 1 3 3 3 0 Tropomyosin like LXG PF04740.12 CBZ33543.1 - 0.063 13.0 0.2 0.063 13.0 0.2 3.0 1 1 1 3 3 3 0 LXG domain of WXG superfamily Syntaxin-6_N PF09177.11 CBZ33543.1 - 0.087 13.4 12.9 0.19 12.3 0.6 3.8 1 1 0 3 3 3 0 Syntaxin 6, N-terminal COG2 PF06148.11 CBZ33543.1 - 0.093 12.8 15.3 1.7 8.8 3.3 4.0 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.22 CBZ33543.1 - 0.096 12.9 11.0 5.5 7.3 1.9 3.5 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RmuC PF02646.16 CBZ33543.1 - 0.1 11.7 10.4 1.6 7.8 0.2 3.6 1 1 1 3 3 3 0 RmuC family FlgN PF05130.12 CBZ33543.1 - 0.11 13.0 14.4 0.97 9.9 0.8 2.9 2 1 1 3 3 3 0 FlgN protein DUF892 PF05974.12 CBZ33543.1 - 0.13 12.3 7.9 4.4 7.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF892) FadA PF09403.10 CBZ33543.1 - 0.13 12.7 6.5 1.7 9.2 0.8 3.2 2 1 1 3 3 3 0 Adhesion protein FadA DUF724 PF05266.14 CBZ33543.1 - 0.15 11.9 0.1 0.15 11.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF724) CK2S PF15011.6 CBZ33543.1 - 0.17 11.8 11.4 0.84 9.5 0.8 2.7 2 1 0 2 2 2 0 Casein Kinase 2 substrate LIF_OSM PF01291.17 CBZ33543.1 - 0.18 11.9 0.9 2.5 8.2 0.1 2.6 2 1 0 2 2 2 0 LIF / OSM family Laminin_II PF06009.12 CBZ33543.1 - 0.2 11.6 13.0 0.28 11.2 0.1 3.5 1 1 1 3 3 3 0 Laminin Domain II AAA_23 PF13476.6 CBZ33543.1 - 0.21 12.1 0.7 3.1 8.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Leu_zip PF15294.6 CBZ33543.1 - 0.22 11.0 11.7 3.5 7.1 4.0 2.9 1 1 1 3 3 3 0 Leucine zipper Phage_GPO PF05929.11 CBZ33543.1 - 0.23 11.1 12.3 1.1 8.8 5.3 2.6 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1043 PF06295.12 CBZ33543.1 - 0.26 11.3 8.9 5.8 6.9 0.1 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF1043) Baculo_p24 PF05073.12 CBZ33543.1 - 0.27 11.0 3.1 6 6.6 0.1 2.3 2 1 0 2 2 2 0 Baculovirus P24 capsid protein Prefoldin_2 PF01920.20 CBZ33543.1 - 0.31 11.0 9.6 5.6 7.0 0.6 3.8 2 2 0 3 3 3 0 Prefoldin subunit Prominin PF05478.11 CBZ33543.1 - 0.54 8.1 3.6 1.7 6.5 0.2 2.2 1 1 2 3 3 3 0 Prominin Golgin_A5 PF09787.9 CBZ33543.1 - 0.58 9.6 17.8 1.5 8.3 9.9 2.5 1 1 0 2 2 2 0 Golgin subfamily A member 5 AAA_27 PF13514.6 CBZ33543.1 - 0.6 9.7 8.1 0.72 9.4 0.4 2.9 2 1 1 3 3 3 0 AAA domain DUF4795 PF16043.5 CBZ33543.1 - 0.67 9.5 15.0 3 7.4 13.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) BshC PF10079.9 CBZ33543.1 - 0.81 8.4 6.9 0.19 10.4 3.3 1.7 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC Atg14 PF10186.9 CBZ33543.1 - 0.88 8.6 10.2 6.3 5.8 4.4 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAUS6_N PF14661.6 CBZ33543.1 - 0.89 9.1 12.0 2.4 7.7 0.2 2.4 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FliD_C PF07195.12 CBZ33543.1 - 0.9 8.9 3.7 9 5.6 0.2 2.8 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ALIX_LYPXL_bnd PF13949.6 CBZ33543.1 - 1.1 8.6 18.6 0.052 12.8 5.2 3.0 1 1 1 3 3 3 0 ALIX V-shaped domain binding to HIV APG6_N PF17675.1 CBZ33543.1 - 1.1 9.8 16.5 17 5.9 12.1 2.9 2 1 0 2 2 2 0 Apg6 coiled-coil region ThiD2 PF17792.1 CBZ33543.1 - 1.2 9.6 13.4 1.7 9.1 7.5 2.5 1 1 1 2 2 2 0 ThiD2 family PhageMin_Tail PF10145.9 CBZ33543.1 - 1.2 8.9 6.7 2.4 7.9 4.3 2.6 1 1 1 2 2 2 0 Phage-related minor tail protein DUF4407 PF14362.6 CBZ33543.1 - 1.3 8.3 18.5 0.39 10.0 2.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_M61 PF05299.12 CBZ33543.1 - 1.4 9.4 3.3 1.5 9.3 0.3 2.5 3 0 0 3 3 2 0 M61 glycyl aminopeptidase TPR_MLP1_2 PF07926.12 CBZ33543.1 - 1.4 9.0 20.0 3 7.9 8.0 3.7 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DASH_Dam1 PF08653.10 CBZ33543.1 - 1.7 8.5 5.0 15 5.5 0.1 4.2 3 2 1 4 4 3 0 DASH complex subunit Dam1 DASH_Dad3 PF08656.10 CBZ33543.1 - 1.7 8.8 4.0 21 5.3 0.1 3.3 2 1 0 2 2 2 0 DASH complex subunit Dad3 DUF2730 PF10805.8 CBZ33543.1 - 1.7 8.7 5.5 1.1 9.4 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) XhlA PF10779.9 CBZ33543.1 - 2.6 8.3 8.1 99 3.3 0.4 4.5 3 1 1 4 4 4 0 Haemolysin XhlA Snapin_Pallidin PF14712.6 CBZ33543.1 - 5.7 7.4 16.5 3.4 8.2 3.4 4.1 2 2 1 3 3 3 0 Snapin/Pallidin CENP-H PF05837.12 CBZ33543.1 - 6.1 7.3 18.2 0.38 11.2 3.8 3.4 2 2 2 4 4 4 0 Centromere protein H (CENP-H) Occludin_ELL PF07303.13 CBZ33543.1 - 7.8 7.3 7.9 11 6.8 1.1 3.1 2 2 2 4 4 2 0 Occludin homology domain GCN5L1 PF06320.13 CBZ33543.1 - 8.5 6.6 10.1 30 4.8 0.3 3.2 1 1 2 3 3 3 0 GCN5-like protein 1 (GCN5L1) PSK_trans_fac PF07704.11 CBZ33543.1 - 9.3 7.1 22.1 0.96 10.3 3.6 4.0 2 1 2 4 4 4 0 Rv0623-like transcription factor Methyltransf_12 PF08242.12 CBZ33544.1 - 8.6e-11 42.5 0.0 1.6e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ33544.1 - 1.5e-10 41.6 0.0 3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ33544.1 - 2.4e-09 37.7 0.0 4.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ33544.1 - 0.00012 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ33544.1 - 0.00042 20.1 0.0 0.00098 18.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ33544.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 CBZ33544.1 - 0.0034 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase EAP30 PF04157.16 CBZ33545.1 - 2.1e-25 89.4 0.9 3.1e-25 88.9 0.9 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 CBZ33545.1 - 1.6e-24 85.9 0.0 2.8e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Ribosomal_S25 PF03297.15 CBZ33545.1 - 8.4e-05 22.7 0.6 0.00025 21.2 0.0 2.1 3 0 0 3 3 3 1 S25 ribosomal protein IRS PF02174.17 CBZ33545.1 - 0.042 13.7 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 PTB domain (IRS-1 type) CAP_N PF01213.19 CBZ33545.1 - 0.23 10.9 2.1 0.16 11.4 0.3 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Mem_trans PF03547.18 CBZ33547.1 - 6.1e-29 100.6 11.6 4.8e-28 97.6 11.6 2.3 1 1 0 1 1 1 1 Membrane transport protein MFS_MOT1 PF16983.5 CBZ33547.1 - 0.22 12.0 4.9 0.84 10.1 0.6 3.0 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily SBF PF01758.16 CBZ33547.1 - 8.6 6.0 17.3 1.6 8.4 4.9 3.1 2 1 0 2 2 2 0 Sodium Bile acid symporter family V-SNARE_C PF12352.8 CBZ33548.1 - 1.5e-09 38.0 4.8 3.7e-09 36.7 2.5 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CBZ33548.1 - 1.4e-05 24.9 0.0 5.1e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Sec20 DUF1691 PF07950.11 CBZ33549.1 - 0.24 12.1 1.9 0.79 10.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) SRP_TPR_like PF17004.5 CBZ33550.1 - 1.1e-11 44.8 3.7 2.6e-11 43.6 2.1 2.5 3 0 0 3 3 3 1 Putative TPR-like repeat ANAPC3 PF12895.7 CBZ33550.1 - 1.3e-07 31.7 20.2 6.1e-06 26.4 5.4 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 SRP72 PF08492.12 CBZ33550.1 - 1e-06 29.1 3.4 1e-06 29.1 3.4 3.2 3 1 2 5 5 5 1 SRP72 RNA-binding domain TPR_19 PF14559.6 CBZ33550.1 - 1.8e-06 28.3 39.9 1.9e-05 25.1 1.3 7.7 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ33550.1 - 0.00052 20.2 6.4 1.7 9.2 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ33550.1 - 0.0084 16.1 10.1 2.3 8.5 1.9 5.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ33550.1 - 0.014 16.1 16.2 0.02 15.5 8.9 7.1 8 1 1 9 9 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ33550.1 - 0.023 14.8 0.0 0.023 14.8 0.0 5.9 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ33550.1 - 0.079 13.2 13.4 2.8 8.4 0.2 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ33550.1 - 0.16 12.2 28.6 2.4 8.5 4.5 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ33550.1 - 0.21 12.5 41.4 2 9.4 3.3 9.6 6 3 3 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ33550.1 - 0.7 10.0 9.8 22 5.2 0.2 5.7 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 CBZ33550.1 - 1.8 8.5 14.5 17 5.4 2.5 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ33550.1 - 7.3 7.5 24.5 18 6.2 1.0 6.6 7 0 0 7 7 5 0 Tetratricopeptide repeat ABC_tran PF00005.27 CBZ33551.1 - 4e-43 147.2 0.0 1.3e-20 74.3 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CBZ33551.1 - 8.8e-23 80.1 4.3 2.6e-21 75.4 1.7 2.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CBZ33551.1 - 8.3e-21 75.1 0.0 5.1e-05 23.2 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ33551.1 - 1.1e-11 44.7 1.1 0.002 17.6 0.0 4.6 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CBZ33551.1 - 3.9e-07 30.4 0.0 0.013 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CBZ33551.1 - 5.5e-07 29.8 0.0 0.039 14.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 CBZ33551.1 - 6.6e-07 30.0 6.9 0.031 14.8 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 CBZ33551.1 - 1.2e-06 29.0 0.0 0.0088 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 CBZ33551.1 - 1.5e-06 28.7 0.0 0.0087 16.5 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBZ33551.1 - 3.2e-06 27.7 0.0 0.037 14.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 CBZ33551.1 - 4.1e-06 27.1 0.1 0.019 15.3 0.0 3.3 4 0 0 4 4 2 2 RNA helicase AAA_29 PF13555.6 CBZ33551.1 - 1.6e-05 24.6 0.1 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CBZ33551.1 - 4.3e-05 23.4 3.8 0.41 10.3 0.0 3.8 4 0 0 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 CBZ33551.1 - 5e-05 23.3 0.0 0.047 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ33551.1 - 6.7e-05 23.2 0.0 0.077 13.3 0.0 2.8 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 CBZ33551.1 - 7e-05 22.8 0.2 0.0053 16.8 0.0 3.0 2 1 1 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CBZ33551.1 - 0.00013 22.0 0.0 2.1 8.4 0.0 3.6 4 0 0 4 4 4 2 AAA domain NACHT PF05729.12 CBZ33551.1 - 0.00016 21.6 0.1 0.26 11.2 0.0 2.8 3 0 0 3 3 3 1 NACHT domain RsgA_GTPase PF03193.16 CBZ33551.1 - 0.00018 21.4 0.0 0.74 9.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 CBZ33551.1 - 0.00023 21.0 0.0 0.1 12.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CBZ33551.1 - 0.00027 20.6 0.0 1.8 8.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_7 PF12775.7 CBZ33551.1 - 0.00065 19.3 0.0 0.12 11.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CBZ33551.1 - 0.00093 19.3 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Rad17 PF03215.15 CBZ33551.1 - 0.00094 19.2 0.1 0.36 10.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain PduV-EutP PF10662.9 CBZ33551.1 - 0.0025 17.6 0.0 0.55 10.0 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.6 CBZ33551.1 - 0.0027 16.5 0.9 2.5 6.7 0.0 3.5 3 1 1 4 4 4 1 AAA domain AAA_30 PF13604.6 CBZ33551.1 - 0.0032 17.2 0.4 1.5 8.5 0.0 3.2 3 1 0 3 3 2 1 AAA domain NB-ARC PF00931.22 CBZ33551.1 - 0.0036 16.5 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain dNK PF01712.19 CBZ33551.1 - 0.012 15.5 0.0 0.69 9.7 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase Mg_chelatase PF01078.21 CBZ33551.1 - 0.016 14.6 0.0 6.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBZ33551.1 - 0.021 14.6 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein RuvB_N PF05496.12 CBZ33551.1 - 0.023 14.4 0.1 0.3 10.8 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 CBZ33551.1 - 0.023 14.6 0.0 2.9 7.8 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 CBZ33551.1 - 0.026 14.1 0.1 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CBZ33551.1 - 0.027 14.7 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 CBZ33551.1 - 0.031 13.9 0.0 14 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CBZ33551.1 - 0.031 13.5 0.0 0.66 9.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 CBZ33551.1 - 0.038 13.6 0.1 0.75 9.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CBZ33551.1 - 0.04 13.8 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 NTPase KapB PF08810.10 CBZ33551.1 - 0.074 13.2 0.1 0.27 11.4 0.0 2.0 2 0 0 2 2 1 0 Kinase associated protein B MeaB PF03308.16 CBZ33551.1 - 0.083 11.9 0.4 1.8 7.5 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_PrkA PF08298.11 CBZ33551.1 - 0.11 11.4 0.0 2.9 6.7 0.0 2.5 3 0 0 3 3 3 0 PrkA AAA domain ATP-synt_ab PF00006.25 CBZ33551.1 - 0.15 11.7 0.0 9.5 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Vps53_N PF04100.12 CBZ33552.1 - 4.8e-66 223.3 10.0 6.7e-66 222.8 10.0 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal COG2 PF06148.11 CBZ33552.1 - 0.021 14.9 1.3 0.059 13.5 1.0 2.0 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_60s PF00428.19 CBZ33552.1 - 0.58 10.8 5.5 3.5 8.3 0.4 3.9 4 0 0 4 4 4 0 60s Acidic ribosomal protein DUF1664 PF07889.12 CBZ33552.1 - 0.82 9.7 3.3 1.7 8.7 2.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Atg8 PF02991.16 CBZ33554.1 - 2.7e-10 40.4 0.0 3.7e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like ExbD PF02472.16 CBZ33554.1 - 0.2 11.9 0.0 0.22 11.7 0.0 1.1 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR BT1 PF03092.16 CBZ33556.1 - 1e-222 740.0 14.9 1.2e-222 739.8 14.9 1.0 1 0 0 1 1 1 1 BT1 family SHE3 PF17078.5 CBZ33557.1 - 0.14 11.9 0.0 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 CAP_GLY PF01302.25 CBZ33558.1 - 3.8e-17 62.0 0.1 6.3e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain DUF1878 PF08963.10 CBZ33558.1 - 5.7 7.5 12.4 1.1 9.8 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1878) Dynein_light PF01221.18 CBZ33560.1 - 7.5e-28 96.7 0.2 8.8e-28 96.5 0.2 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 FKBP_C PF00254.28 CBZ33561.1 - 1.5e-12 47.7 0.0 2.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FYVE PF01363.21 CBZ33562.1 - 5e-15 55.4 5.4 1.9e-14 53.5 5.4 2.0 1 1 0 1 1 1 1 FYVE zinc finger PRP3 PF08572.10 CBZ33562.1 - 0.041 13.6 0.1 0.62 9.8 0.2 2.2 2 0 0 2 2 2 0 pre-mRNA processing factor 3 (PRP3) AMP-binding PF00501.28 CBZ33563.1 - 1.1e-89 301.0 1.5 1.3e-89 300.8 1.5 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBZ33563.1 - 4.3e-12 46.8 0.0 1.1e-11 45.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CBZ33566.1 - 7.8e-80 268.5 0.1 9.6e-80 268.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CBZ33566.1 - 1.2e-11 45.4 0.0 4.7e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 CBZ33567.1 - 4.8e-16 58.8 2.5 0.00044 21.0 0.6 7.7 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ33567.1 - 0.014 15.7 0.0 27 5.2 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ33567.1 - 0.027 13.1 0.1 0.35 9.4 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.11 CBZ33567.1 - 0.09 12.6 0.0 0.91 9.4 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 CBZ33567.1 - 0.13 11.5 0.0 3.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus EAGR_box PF16713.5 CBZ33567.1 - 0.22 11.2 0.3 0.37 10.5 0.3 1.3 1 0 0 1 1 1 0 Enriched in aromatic and glycine Residues box PseudoU_synth_1 PF01416.20 CBZ33568.1 - 1.2e-13 51.5 0.0 1.1e-11 45.2 0.0 2.7 2 0 0 2 2 2 1 tRNA pseudouridine synthase TP1 PF02079.16 CBZ33568.1 - 0.029 14.3 0.1 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 Nuclear transition protein 1 Cir_N PF10197.9 CBZ33569.1 - 0.00011 22.2 5.2 0.00011 22.2 5.2 3.4 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR GAS PF13851.6 CBZ33569.1 - 0.23 10.8 17.5 0.2 11.0 4.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding 5_nucleotid PF05761.14 CBZ33569.1 - 3.1 6.6 5.9 15 4.4 0.1 2.1 2 0 0 2 2 2 0 5' nucleotidase family tRNA_synthFbeta PF17759.1 CBZ33570.1 - 3.1e-39 134.6 0.0 4.7e-39 134.0 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CBZ33570.1 - 5.2e-30 103.5 0.1 1.9e-29 101.7 0.0 1.9 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 CBZ33570.1 - 1.5e-20 73.2 0.0 1.9e-15 56.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain B3_4 PF03483.17 CBZ33570.1 - 6.1e-18 65.1 0.0 1.1e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain DUF3381 PF11861.8 CBZ33571.1 - 0.51 10.1 3.7 0.24 11.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Pex19 PF04614.12 CBZ33572.1 - 0.83 9.4 18.6 5.8 6.6 2.7 4.4 2 2 1 3 3 3 0 Pex19 protein family SOGA PF11365.8 CBZ33572.1 - 1.1 10.4 7.0 2.5 9.3 1.6 3.6 2 1 1 3 3 3 0 Protein SOGA DUF2497 PF10691.9 CBZ33572.1 - 5.6 7.5 10.9 2.1 8.8 0.1 4.9 4 1 0 4 4 4 0 Protein of unknown function (DUF2497) DAGK_cat PF00781.24 CBZ33573.1 - 1.7e-11 43.8 0.0 2.3e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 Diacylglycerol kinase catalytic domain Anillin_N PF16018.5 CBZ33573.1 - 0.14 12.8 1.6 0.41 11.3 0.4 2.4 2 0 0 2 2 2 0 Anillin N-terminus DUF1664 PF07889.12 CBZ33576.1 - 6.4 6.8 7.4 26 4.8 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) betaPIX_CC PF16523.5 CBZ33576.1 - 6.5 6.6 10.5 1.9 8.3 1.2 3.4 3 1 0 3 3 3 0 betaPIX coiled coil Mito_carr PF00153.27 CBZ33577.1 - 7.4e-52 173.2 6.3 7.7e-18 64.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PCI PF01399.27 CBZ33578.1 - 3.2e-08 34.0 0.0 1.1e-07 32.3 0.0 2.0 1 0 0 1 1 1 1 PCI domain Ank_2 PF12796.7 CBZ33579.1 - 1.6e-26 92.7 22.1 8.4e-07 29.5 0.2 10.7 9 2 1 11 11 11 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ33579.1 - 2e-13 49.2 30.4 0.027 15.0 0.1 14.8 15 0 0 15 15 15 4 Ankyrin repeat Ank PF00023.30 CBZ33579.1 - 7.6e-13 48.3 22.0 0.0042 17.5 0.2 10.3 10 0 0 10 10 10 4 Ankyrin repeat Ank_4 PF13637.6 CBZ33579.1 - 1.6e-09 38.1 14.1 0.034 14.7 0.1 10.2 11 0 0 11 11 11 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ33579.1 - 0.00011 22.4 20.4 0.6 10.5 0.1 9.8 10 1 1 11 11 11 2 Ankyrin repeats (many copies) DUF2456 PF10445.9 CBZ33580.1 - 0.51 10.5 3.3 0.4 10.8 2.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) Spem1 PF15670.5 CBZ33581.1 - 0.68 9.5 3.2 1.6 8.3 3.2 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 DNA_pol3_alpha PF07733.12 CBZ33583.1 - 0.02 14.5 0.2 0.02 14.5 0.2 2.1 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha NTPase domain Lzipper-MIP1 PF14389.6 CBZ33584.1 - 0.43 10.9 7.2 2 8.8 0.1 3.3 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CHCH PF06747.13 CBZ33586.1 - 1.2e-06 28.5 1.7 2e-06 27.8 1.7 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 CBZ33586.1 - 0.0014 18.6 1.0 0.0028 17.6 1.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 CBZ33586.1 - 0.0051 17.1 2.3 0.062 13.7 0.6 2.3 1 1 1 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) NDUF_B7 PF05676.13 CBZ33586.1 - 0.0061 16.3 1.9 0.01 15.5 1.9 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MTCP1 PF08991.10 CBZ33586.1 - 0.018 15.2 0.2 0.027 14.7 0.2 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type COX6B PF02297.17 CBZ33586.1 - 0.045 14.0 0.9 0.074 13.3 0.9 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 CBZ33586.1 - 0.19 12.1 2.5 0.43 10.9 2.5 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Actin PF00022.19 CBZ33587.1 - 7.1e-75 252.1 0.0 8.6e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CBZ33587.1 - 0.13 11.1 0.0 5.1 5.8 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Fcf1 PF04900.12 CBZ33588.1 - 4.3e-31 107.2 2.6 8.1e-31 106.4 2.6 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CBZ33588.1 - 2.5e-13 50.4 0.0 4.5e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 PIN like domain Thioredoxin PF00085.20 CBZ33589.1 - 0.012 15.5 0.1 0.026 14.5 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin DUF5544 PF17698.1 CBZ33589.1 - 0.018 15.2 0.9 0.031 14.4 0.7 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5544) TPR_4 PF07721.14 CBZ33589.1 - 0.03 14.9 1.1 0.062 14.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ33589.1 - 0.033 14.1 0.4 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat NMD3 PF04981.13 CBZ33589.1 - 0.053 13.0 0.3 0.14 11.6 0.3 1.7 1 1 1 2 2 2 0 NMD3 family Castor1_N PF18700.1 CBZ33589.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Pex2_Pex12 PF04757.14 CBZ33592.1 - 1.1e-34 120.0 0.0 2.6e-34 118.8 0.0 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CBZ33592.1 - 0.0058 16.5 4.6 0.011 15.5 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ33592.1 - 0.055 13.8 2.2 0.1 13.0 2.2 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ33592.1 - 0.15 11.9 2.0 0.31 10.9 2.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) NMD3 PF04981.13 CBZ33593.1 - 0.053 13.0 0.5 0.098 12.1 0.5 1.4 1 0 0 1 1 1 0 NMD3 family DZR PF12773.7 CBZ33593.1 - 0.095 12.7 0.2 0.17 11.9 0.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Mss51 PF13824.6 CBZ33593.1 - 0.11 12.6 0.3 0.22 11.7 0.3 1.7 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf_C2H2_13 PF18508.1 CBZ33593.1 - 3.3 7.4 4.6 14 5.3 0.1 2.2 1 1 1 2 2 2 0 Zinc finger domain Surp PF01805.20 CBZ33594.1 - 2.9e-13 49.6 0.6 2.9e-13 49.6 0.6 2.0 2 0 0 2 2 2 1 Surp module Band_7 PF01145.25 CBZ33595.1 - 7.3e-28 97.8 0.1 2.2e-27 96.2 0.0 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CBZ33595.1 - 0.0058 16.4 0.3 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 SPFH domain-Band 7 family Band_7 PF01145.25 CBZ33596.1 - 1.8e-22 80.2 0.0 2.7e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family MVP_shoulder PF11978.8 CBZ33596.1 - 0.13 12.3 0.0 0.63 10.1 0.1 2.1 2 0 0 2 2 2 0 Shoulder domain Pkinase PF00069.25 CBZ33597.1 - 9e-05 22.0 0.0 0.00033 20.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33597.1 - 0.012 14.9 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Calsequestrin PF01216.17 CBZ33598.1 - 0.091 11.8 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Calsequestrin SH3_4 PF06347.13 CBZ33598.1 - 0.22 11.4 1.3 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial SH3 domain MBOAT PF03062.19 CBZ33602.1 - 7.6e-25 88.0 26.5 1e-21 77.7 10.2 3.2 2 1 0 3 3 3 2 MBOAT, membrane-bound O-acyltransferase family Viral_Beta_CD PF04530.12 CBZ33602.1 - 0.023 15.0 0.8 2.8 8.3 0.2 3.1 3 0 0 3 3 3 0 Viral Beta C/D like family DUF1180 PF06679.12 CBZ33602.1 - 1.6 9.1 3.7 1.9 8.9 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) PAP2 PF01569.21 CBZ33603.1 - 3.5e-25 88.4 3.1 3.5e-25 88.4 3.1 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CBZ33603.1 - 0.14 11.8 14.5 0.04 13.6 8.5 2.7 2 1 0 2 2 2 0 PAP2 superfamily DUF4131 PF13567.6 CBZ33603.1 - 0.71 9.5 6.1 1.3 8.7 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2637 PF10935.8 CBZ33603.1 - 1.3 8.9 3.9 10 6.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2637) Gpr1_Fun34_YaaH PF01184.19 CBZ33603.1 - 4.1 6.9 8.3 0.12 12.0 0.4 2.3 3 0 0 3 3 3 0 GPR1/FUN34/yaaH family RDD PF06271.12 CBZ33603.1 - 5.5 7.2 8.2 1.1 9.4 2.8 2.2 2 0 0 2 2 2 0 RDD family DUF2207 PF09972.9 CBZ33604.1 - 0.029 13.1 0.3 0.033 13.0 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TrkH PF02386.16 CBZ33604.1 - 0.039 12.4 0.2 0.044 12.2 0.2 1.1 1 0 0 1 1 1 0 Cation transport protein ISK_Channel PF02060.15 CBZ33604.1 - 0.07 12.8 0.1 0.084 12.6 0.1 1.1 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Pex2_Pex12 PF04757.14 CBZ33604.1 - 0.072 12.7 0.0 0.077 12.6 0.0 1.0 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region Wzy_C PF04932.15 CBZ33604.1 - 0.085 12.5 0.6 0.098 12.3 0.6 1.1 1 0 0 1 1 1 0 O-Antigen ligase Sigma_reg_N PF13800.6 CBZ33604.1 - 0.33 11.3 1.7 0.5 10.7 0.4 1.8 2 0 0 2 2 2 0 Sigma factor regulator N-terminal SLC3A2_N PF16028.5 CBZ33604.1 - 1 9.0 3.9 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus TMEM154 PF15102.6 CBZ33604.1 - 1 9.3 2.9 0.57 10.1 0.5 1.6 1 1 1 2 2 2 0 TMEM154 protein family SecG PF03840.14 CBZ33604.1 - 1.1 9.4 8.2 3.6 7.7 8.2 1.8 1 1 0 1 1 1 0 Preprotein translocase SecG subunit FixP_N PF14715.6 CBZ33604.1 - 1.6 8.5 8.8 3.1 7.6 8.8 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP OppC_N PF12911.7 CBZ33604.1 - 4.1 7.4 8.3 3.1 7.9 1.5 2.3 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF641 PF04859.12 CBZ33606.1 - 2.2e-05 24.8 0.9 0.00045 20.6 0.1 2.6 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) PDZ_6 PF17820.1 CBZ33606.1 - 0.00032 20.5 0.0 0.00087 19.1 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CBZ33606.1 - 0.016 15.5 0.0 0.056 13.8 0.0 1.9 2 0 0 2 2 2 0 PDZ domain PDZ PF00595.24 CBZ33606.1 - 0.078 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 PDZ domain Glyco_hydro_85 PF03644.13 CBZ33606.1 - 0.24 10.8 0.1 0.4 10.1 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 SlyX PF04102.12 CBZ33606.1 - 0.73 10.5 7.7 1.1 10.0 0.2 3.3 3 0 0 3 3 3 0 SlyX DUF4407 PF14362.6 CBZ33606.1 - 3.3 7.0 5.2 1.1 8.6 0.8 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Cation_efflux PF01545.21 CBZ33607.1 - 5.4e-31 107.9 7.8 1.1e-19 70.9 2.5 2.2 2 0 0 2 2 2 2 Cation efflux family TBP PF00352.21 CBZ33608.1 - 7.9e-42 141.1 0.1 9.8e-24 83.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) TPR_11 PF13414.6 CBZ33609.1 - 3e-10 39.6 0.0 0.006 16.2 0.0 4.3 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.28 CBZ33609.1 - 4.3e-08 32.6 1.7 0.0012 18.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ33609.1 - 6.4e-08 32.1 6.7 0.0032 17.4 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ33609.1 - 1.8e-07 31.0 0.9 0.022 15.1 0.0 3.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ33609.1 - 2.5e-07 30.4 1.3 0.0041 17.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ33609.1 - 7.5e-05 22.9 0.1 0.0014 18.8 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ33609.1 - 0.00023 21.7 0.1 0.81 10.7 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 CBZ33609.1 - 0.0026 17.5 0.1 0.0039 16.9 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain Sel1 PF08238.12 CBZ33609.1 - 0.0064 17.1 1.0 1.9 9.3 0.0 3.3 3 0 0 3 3 3 1 Sel1 repeat TPR_16 PF13432.6 CBZ33609.1 - 0.013 16.1 0.0 0.56 10.9 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ33609.1 - 0.019 15.6 0.7 8.9 7.2 0.0 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ33609.1 - 0.05 13.5 0.0 0.57 10.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat PAP_assoc PF03828.19 CBZ33610.1 - 4.5e-14 52.4 0.1 1.1e-13 51.1 0.1 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Peptidase_C1 PF00112.23 CBZ33611.1 - 1.2e-68 231.5 1.3 1.6e-68 231.1 1.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 CBZ33611.1 - 2.4e-07 31.1 0.3 2.4e-07 31.1 0.3 1.8 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 CBZ33611.1 - 6.4e-06 25.2 0.5 0.0035 16.2 0.0 2.4 3 0 0 3 3 3 2 Peptidase C1-like family PIH1 PF08190.12 CBZ33612.1 - 2.7e-08 33.5 0.0 4.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 CBZ33612.1 - 0.015 15.7 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 PIH1 CS-like domain Pkinase PF00069.25 CBZ33613.1 - 2e-66 224.1 0.0 2.4e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33613.1 - 1.4e-33 116.3 0.0 2e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ33613.1 - 2e-06 27.3 0.0 3.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ33613.1 - 0.0017 18.3 0.8 0.0024 17.8 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ33613.1 - 0.0073 15.7 0.3 0.013 14.9 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ33613.1 - 0.031 13.2 0.1 0.043 12.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Oxidored-like PF09791.9 CBZ33614.1 - 5.8e-12 45.1 1.3 1.4e-11 43.8 1.3 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal NAD_binding_1 PF00175.21 CBZ33614.1 - 9.8e-12 45.5 0.0 2.2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 CBZ33614.1 - 8e-07 28.8 0.0 0.00093 18.8 0.1 2.3 1 1 0 2 2 2 2 FAD binding domain DUF5522 PF17653.1 CBZ33614.1 - 0.27 11.2 3.0 0.6 10.1 3.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5522) COX6B PF02297.17 CBZ33615.1 - 0.083 13.1 2.3 0.19 12.0 2.3 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.25 CBZ33616.1 - 1.4e-42 145.9 0.0 5.5e-29 101.3 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33616.1 - 1.2e-16 60.7 0.0 3e-14 52.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ33616.1 - 0.037 12.8 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase IF4E PF01652.18 CBZ33617.1 - 2.2e-40 138.0 0.2 3.2e-40 137.5 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TPT PF03151.16 CBZ33619.1 - 1e-19 71.0 21.8 1.2e-19 70.8 21.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBZ33619.1 - 2.5e-05 24.5 11.1 2.5e-05 24.5 11.1 2.4 1 1 0 2 2 2 2 EamA-like transporter family IF3_N PF05198.16 CBZ33620.1 - 0.041 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain FKBP_C PF00254.28 CBZ33621.1 - 2.6e-31 107.8 0.0 1.1e-30 105.8 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 CBZ33621.1 - 1.7e-10 40.2 0.1 0.00057 19.8 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ33621.1 - 1.9e-09 36.9 0.1 0.013 15.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ33621.1 - 1.6e-06 28.6 1.5 5.8e-06 26.7 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ33621.1 - 2.8e-06 27.5 0.0 0.92 9.8 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ33621.1 - 0.00033 21.2 2.4 0.0097 16.7 0.2 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ33621.1 - 0.00036 20.5 0.0 0.0014 18.6 0.0 2.0 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 CBZ33621.1 - 0.00042 20.5 0.4 0.82 10.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ33621.1 - 0.00063 20.3 0.6 0.73 10.5 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ33621.1 - 0.0018 18.2 0.2 0.45 10.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ33621.1 - 0.0035 17.5 0.1 0.013 15.7 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CBZ33621.1 - 0.0051 16.9 0.1 31 5.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ33621.1 - 0.011 15.6 0.3 2.1 8.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Carn_acyltransf PF00755.20 CBZ33623.1 - 1.5e-148 496.1 0.0 2.2e-148 495.5 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase WD40 PF00400.32 CBZ33624.1 - 9e-11 42.2 1.6 0.00045 21.0 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ33624.1 - 7.7e-07 29.3 0.0 0.00018 21.8 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 CBZ33624.1 - 0.034 13.4 0.0 0.068 12.4 0.0 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus IMPDH PF00478.25 CBZ33625.1 - 5e-123 410.5 3.9 5.9e-123 410.3 3.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CBZ33625.1 - 1.9e-13 50.6 0.3 2.6e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CBZ33625.1 - 1.5e-10 40.7 0.2 1.5e-10 40.7 0.2 1.6 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CBZ33625.1 - 0.00011 21.8 3.1 0.19 11.1 2.8 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 CBZ33625.1 - 0.024 14.1 0.2 0.49 9.8 0.0 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein Formyl_trans_C PF02911.18 CBZ33625.1 - 0.16 12.3 0.0 5 7.4 0.0 2.5 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain ELMO_CED12 PF04727.13 CBZ33626.1 - 7e-28 97.9 0.0 1e-27 97.4 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family Transketolase_C PF02780.20 CBZ33626.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Transketolase, C-terminal domain Peptidase_M41 PF01434.18 CBZ33628.1 - 2e-41 142.0 0.4 3.3e-41 141.2 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBZ33628.1 - 1e-40 139.2 0.0 1.9e-39 135.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ33628.1 - 0.00065 20.0 1.7 0.0073 16.6 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 CBZ33628.1 - 0.00085 19.1 0.2 0.004 16.9 0.2 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBZ33628.1 - 0.0014 18.6 0.3 0.023 14.7 0.3 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ33628.1 - 0.0016 18.8 8.2 0.015 15.6 0.4 3.8 2 2 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CBZ33628.1 - 0.0054 16.5 0.0 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBZ33628.1 - 0.016 14.4 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Peptidase_M50B PF13398.6 CBZ33628.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase M50B-like IstB_IS21 PF01695.17 CBZ33628.1 - 0.031 14.0 0.1 0.075 12.8 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 CBZ33628.1 - 0.082 12.1 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CBZ33628.1 - 0.12 12.3 0.1 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 CBZ33628.1 - 0.15 12.2 0.1 1.1 9.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 CBZ33628.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP19 PF01922.17 CBZ33629.1 - 2.1e-21 76.7 0.1 2.9e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 SRP19 protein Pkinase PF00069.25 CBZ33630.1 - 2e-20 73.2 0.0 2.5e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33630.1 - 9.9e-06 25.0 0.0 3e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ33630.1 - 0.0071 15.2 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase BTB_2 PF02214.22 CBZ33631.1 - 2.2e-12 47.1 0.0 5.7e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Atg8 PF02991.16 CBZ33632.1 - 1.8e-38 130.9 0.0 2.1e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CBZ33632.1 - 1.1e-07 32.1 0.0 1.4e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 LRR_4 PF12799.7 CBZ33633.1 - 1.9e-23 82.1 0.0 9.1e-07 29.1 0.1 8.0 4 2 6 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ33633.1 - 9.7e-10 38.1 0.1 0.023 14.4 0.0 6.0 6 1 1 7 7 7 2 Leucine rich repeat LRR_6 PF13516.6 CBZ33633.1 - 5.4e-05 22.9 2.4 14 6.0 0.0 7.1 8 0 0 8 8 8 2 Leucine Rich repeat zf-C3HC4_2 PF13923.6 CBZ33633.1 - 1.5 8.7 11.7 9.5 6.2 11.7 2.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ33633.1 - 4.3 7.3 10.5 17 5.4 10.5 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ubiq_cyt_C_chap PF03981.12 CBZ33634.1 - 0.081 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Ubiq_cyt_C_chap PF03981.12 CBZ33635.1 - 0.081 13.0 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone WD40 PF00400.32 CBZ33636.1 - 2.2e-16 59.9 6.6 4.3e-05 24.2 0.3 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ33636.1 - 8.5e-06 26.0 0.0 0.35 11.2 0.0 3.2 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ33636.1 - 0.052 12.2 4.3 0.27 9.8 0.2 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Hira PF07569.11 CBZ33636.1 - 0.084 12.6 0.4 16 5.1 0.0 2.8 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF1500 PF07389.12 CBZ33636.1 - 0.13 12.3 0.1 0.57 10.3 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1500) WD40_like PF17005.5 CBZ33636.1 - 0.14 11.4 0.1 0.81 9.0 0.1 2.0 1 1 1 2 2 2 0 WD40-like domain DOT1 PF08123.13 CBZ33637.1 - 5.7e-19 68.4 0.0 8e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 CBZ33637.1 - 7.9e-05 22.5 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ33637.1 - 0.00013 22.6 0.0 0.00023 21.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ33637.1 - 0.0002 21.9 0.0 0.00045 20.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ33637.1 - 0.0051 16.7 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBZ33637.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CBZ33637.1 - 0.034 14.9 0.0 0.06 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 CBZ33637.1 - 0.041 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AdoMet_MTase PF07757.13 CBZ33637.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase UPF0020 PF01170.18 CBZ33637.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PHO4 PF01384.20 CBZ33638.1 - 5e-107 357.8 21.1 6.1e-107 357.6 21.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family ASF1_hist_chap PF04729.13 CBZ33640.1 - 6e-45 152.9 0.0 7.3e-45 152.7 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone TetR_C_30 PF17939.1 CBZ33640.1 - 0.048 13.9 0.2 7.4 6.8 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain BRCA-2_OB1 PF09103.10 CBZ33641.1 - 7.6e-24 84.0 0.0 1.3e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 CBZ33641.1 - 1.9e-08 33.9 0.0 0.0001 21.9 0.0 2.5 2 0 0 2 2 2 2 BRCA2 repeat zf-RanBP PF00641.18 CBZ33641.1 - 0.029 13.7 2.6 0.081 12.3 2.6 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others MRG PF05712.13 CBZ33642.1 - 0.0038 16.6 0.0 0.0042 16.4 0.0 1.1 1 0 0 1 1 1 1 MRG Ion_trans_2 PF07885.16 CBZ33644.1 - 1e-12 47.8 6.3 1e-12 47.8 6.3 2.5 2 0 0 2 2 2 1 Ion channel BK_channel_a PF03493.18 CBZ33644.1 - 1.1e-12 48.0 0.0 2.3e-11 43.7 0.0 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit PGK PF00162.19 CBZ33645.1 - 9.5e-156 518.5 0.0 1.1e-155 518.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PGK PF00162.19 CBZ33646.1 - 4.6e-30 104.8 0.0 5.1e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase AAA_16 PF13191.6 CBZ33647.1 - 1.4e-06 28.8 1.2 0.00018 21.9 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain NB-ARC PF00931.22 CBZ33647.1 - 2.7e-06 26.8 0.0 0.015 14.5 0.0 2.2 1 1 1 2 2 2 2 NB-ARC domain AAA_25 PF13481.6 CBZ33647.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ33647.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 CBZ33647.1 - 0.025 15.0 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CBZ33647.1 - 0.036 14.0 0.0 0.25 11.3 0.0 2.1 1 1 1 2 2 2 0 NACHT domain AAA_14 PF13173.6 CBZ33647.1 - 0.055 13.5 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBZ33647.1 - 0.1 12.5 0.0 2.7 7.9 0.0 2.3 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CBZ33647.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CBZ33647.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 CBZ33647.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase TetR_C_11 PF16859.5 CBZ33647.1 - 3.5 8.0 8.2 1.6 9.1 0.6 3.5 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain MORN PF02493.20 CBZ33648.1 - 4.1e-11 42.1 13.3 1.6e-06 27.6 0.0 6.8 7 1 0 7 7 7 3 MORN repeat RIB43A PF05914.12 CBZ33648.1 - 0.059 12.1 5.8 0.083 11.6 5.8 1.1 1 0 0 1 1 1 0 RIB43A DUF1736 PF08409.11 CBZ33650.1 - 1.7e-17 63.2 0.3 1.7e-17 63.2 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1736) Fez1 PF06818.15 CBZ33651.1 - 0.009 16.5 13.0 0.018 15.5 9.9 2.3 2 0 0 2 2 2 1 Fez1 Ada3 PF10198.9 CBZ33651.1 - 0.013 15.7 4.5 0.039 14.1 4.5 1.8 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 TMF_TATA_bd PF12325.8 CBZ33651.1 - 0.023 14.9 19.4 0.095 12.9 6.3 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.6 CBZ33651.1 - 0.21 10.2 8.7 0.37 9.4 8.7 1.3 1 0 0 1 1 1 0 AAA domain SOGA PF11365.8 CBZ33651.1 - 0.52 11.5 13.6 10 7.3 0.2 2.8 2 1 0 2 2 2 0 Protein SOGA Chlorosome_CsmC PF11098.8 CBZ33651.1 - 0.62 10.0 6.6 0.72 9.8 2.3 2.4 2 0 0 2 2 2 0 Chlorosome envelope protein C DUF4201 PF13870.6 CBZ33651.1 - 1.5 8.5 10.4 0.61 9.8 3.9 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4763 PF15960.5 CBZ33651.1 - 2.3 7.5 11.5 0.23 10.8 6.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Spc7 PF08317.11 CBZ33651.1 - 2.7 6.8 22.1 0.093 11.6 13.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Mto2_bdg PF12808.7 CBZ33651.1 - 2.8 8.3 9.0 1.5 9.2 3.9 3.2 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3450 PF11932.8 CBZ33651.1 - 4.2 6.6 20.9 0.64 9.3 13.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Rx_N PF18052.1 CBZ33651.1 - 4.7 7.5 16.7 2.2 8.6 0.6 4.3 3 1 2 5 5 5 0 Rx N-terminal domain Atg14 PF10186.9 CBZ33651.1 - 5 6.1 10.5 7.9 5.5 10.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 CBZ33651.1 - 5.2 7.8 10.0 32 5.2 2.9 3.2 3 0 0 3 3 3 0 Initiation control protein YabA TolA_bind_tri PF16331.5 CBZ33651.1 - 9.2 6.4 24.2 0.12 12.4 0.3 4.7 5 1 1 6 6 5 0 TolA binding protein trimerisation UT PF03253.14 CBZ33652.1 - 0.027 13.6 0.0 0.043 12.9 0.0 1.2 1 0 0 1 1 1 0 Urea transporter Kelch_6 PF13964.6 CBZ33656.1 - 6.7e-27 92.9 4.5 6.7e-05 23.0 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CBZ33656.1 - 5e-24 83.6 18.1 3e-08 33.1 0.2 6.9 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 CBZ33656.1 - 1.2e-23 82.9 11.9 5e-05 23.5 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ33656.1 - 7.8e-22 76.8 7.9 6.2e-05 22.9 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 CBZ33656.1 - 5.8e-18 64.6 0.5 0.00014 21.8 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CBZ33656.1 - 1.1e-11 44.1 22.5 0.012 15.5 0.9 7.2 6 3 0 6 6 6 5 Kelch motif PQQ_3 PF13570.6 CBZ33656.1 - 6.4 7.4 5.6 19 5.9 0.0 4.1 4 1 1 5 5 5 0 PQQ-like domain DUF2267 PF10025.9 CBZ33657.1 - 1.7 8.9 8.7 2.6 8.3 2.9 3.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) DS PF01916.17 CBZ33660.1 - 1e-86 290.8 0.0 1.2e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase Peptidase_S49_N PF08496.10 CBZ33660.1 - 0.18 11.9 0.2 7.6 6.6 0.2 2.1 1 1 1 2 2 2 0 Peptidase family S49 N-terminal AAA_5 PF07728.14 CBZ33661.1 - 7.7e-124 408.2 0.0 4.2e-23 81.9 0.0 8.7 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CBZ33661.1 - 3.5e-43 146.1 4.7 5.2e-13 49.1 0.1 5.3 4 0 0 4 4 4 4 Midasin AAA lid domain AAA_3 PF07726.11 CBZ33661.1 - 2.3e-27 95.4 0.0 0.0015 18.4 0.0 8.4 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CBZ33661.1 - 1.1e-24 86.9 0.5 8.9e-05 22.1 0.0 6.6 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_lid_5 PF17865.1 CBZ33661.1 - 9.3e-22 77.1 0.0 3.4e-21 75.3 0.0 2.1 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_6 PF12774.7 CBZ33661.1 - 1.5e-21 76.7 0.1 0.0079 15.2 0.0 8.4 9 0 0 9 9 9 5 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 CBZ33661.1 - 2.2e-21 76.6 0.0 0.0032 17.7 0.0 7.5 6 0 0 6 6 6 4 AAA domain AAA PF00004.29 CBZ33661.1 - 4.2e-21 75.8 0.1 0.0017 18.8 0.0 7.4 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ33661.1 - 1.4e-19 71.1 29.1 0.00019 21.8 0.0 10.6 11 1 0 11 11 7 5 AAA ATPase domain Dynein_heavy PF03028.15 CBZ33661.1 - 5.5e-18 65.2 0.0 0.023 14.8 0.0 6.1 5 0 0 5 5 5 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 CBZ33661.1 - 1.7e-15 57.1 0.0 0.014 15.1 0.0 6.6 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_30 PF13604.6 CBZ33661.1 - 3.7e-15 56.2 0.0 0.0084 15.8 0.0 8.0 7 1 1 8 8 8 2 AAA domain AAA_14 PF13173.6 CBZ33661.1 - 1.4e-12 47.8 0.0 0.011 15.8 0.0 6.2 6 0 0 6 6 5 2 AAA domain TsaE PF02367.17 CBZ33661.1 - 3.9e-12 46.3 3.8 0.019 14.9 0.0 6.5 6 0 0 6 6 6 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CBZ33661.1 - 3.2e-10 40.3 0.3 0.0012 19.0 0.0 5.3 6 0 0 6 6 5 2 Sigma-54 interaction domain AAA_18 PF13238.6 CBZ33661.1 - 6.1e-10 39.7 0.2 1.4 9.5 0.0 7.1 6 1 0 6 6 6 3 AAA domain IstB_IS21 PF01695.17 CBZ33661.1 - 4.1e-09 36.4 0.3 0.21 11.3 0.0 4.9 5 0 0 5 5 4 3 IstB-like ATP binding protein AAA_29 PF13555.6 CBZ33661.1 - 4.4e-09 35.9 0.7 13 5.6 0.0 6.6 6 0 0 6 6 6 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CBZ33661.1 - 5.8e-09 36.6 13.4 0.44 11.1 0.0 7.3 7 0 0 7 7 6 2 ABC transporter Zeta_toxin PF06414.12 CBZ33661.1 - 1.1e-08 34.6 0.7 0.2 10.9 0.0 6.0 6 0 0 6 6 6 2 Zeta toxin Rad17 PF03215.15 CBZ33661.1 - 4.1e-08 33.4 1.2 5.4 6.9 0.0 6.1 6 0 0 6 6 6 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 CBZ33661.1 - 4.5e-08 33.2 5.5 1.1 9.2 0.0 5.9 6 0 0 6 6 5 3 RsgA GTPase RNA_helicase PF00910.22 CBZ33661.1 - 1.4e-07 31.9 0.8 0.43 11.0 0.0 6.3 7 0 0 7 7 5 1 RNA helicase DUF815 PF05673.13 CBZ33661.1 - 2.3e-07 30.2 3.9 0.24 10.5 0.0 5.0 6 0 0 6 6 4 2 Protein of unknown function (DUF815) T2SSE PF00437.20 CBZ33661.1 - 2.9e-07 29.8 3.7 0.23 10.5 0.0 5.9 6 0 0 6 6 6 2 Type II/IV secretion system protein AAA_25 PF13481.6 CBZ33661.1 - 3.3e-07 30.1 4.5 0.23 11.0 0.0 6.1 6 0 0 6 6 5 1 AAA domain Mg_chelatase PF01078.21 CBZ33661.1 - 1.2e-06 28.1 2.8 8.8 5.6 0.0 7.6 9 0 0 9 9 8 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CBZ33661.1 - 2.3e-06 27.8 6.0 11 6.2 0.0 7.0 7 0 0 7 7 6 0 AAA domain RuvB_N PF05496.12 CBZ33661.1 - 7.4e-06 25.8 0.4 0.61 9.8 0.0 5.4 7 0 0 7 7 5 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 CBZ33661.1 - 1.4e-05 25.1 1.9 1.3 8.9 0.0 5.6 6 0 0 6 6 6 1 NACHT domain AAA_8 PF12780.7 CBZ33661.1 - 2e-05 24.0 0.2 3.1 7.0 0.0 5.0 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 CPT PF07931.12 CBZ33661.1 - 0.00056 19.8 3.2 0.53 10.1 0.0 4.6 6 0 0 6 6 4 1 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 CBZ33661.1 - 0.00059 19.8 1.0 1.4 8.8 0.0 4.3 4 0 0 4 4 4 1 NTPase MeaB PF03308.16 CBZ33661.1 - 0.0019 17.2 1.5 0.48 9.4 0.1 3.6 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 CBZ33661.1 - 0.0043 17.4 6.4 12 6.2 0.0 6.1 6 0 0 6 6 5 0 AAA domain ResIII PF04851.15 CBZ33661.1 - 0.0064 16.5 5.1 1 9.4 0.0 4.9 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit TniB PF05621.11 CBZ33661.1 - 0.0072 15.8 0.1 1.3 8.4 0.0 4.4 6 0 0 6 6 4 1 Bacterial TniB protein dNK PF01712.19 CBZ33661.1 - 0.0098 15.8 1.1 16 5.3 0.0 4.1 4 0 0 4 4 4 0 Deoxynucleoside kinase PduV-EutP PF10662.9 CBZ33661.1 - 0.037 13.8 0.9 44 3.8 0.0 4.7 7 0 0 7 7 4 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 CBZ33661.1 - 0.058 13.3 0.0 7.9 6.3 0.0 3.8 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 CBZ33661.1 - 0.073 12.3 1.3 13 4.8 0.0 4.0 5 0 0 5 5 5 0 TIP49 P-loop domain AAA_21 PF13304.6 CBZ33661.1 - 0.12 12.1 0.0 2.3 7.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SRP54 PF00448.22 CBZ33661.1 - 0.35 10.5 5.1 81 2.7 0.1 4.8 5 0 0 5 5 5 0 SRP54-type protein, GTPase domain PhoH PF02562.16 CBZ33661.1 - 0.53 9.7 7.7 7 6.0 0.0 4.4 6 0 0 6 6 3 0 PhoH-like protein Roc PF08477.13 CBZ33661.1 - 0.56 10.4 2.2 56 4.0 0.0 4.4 5 0 0 5 5 4 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 CBZ33661.1 - 2.4 8.2 4.3 2.3 8.3 0.0 3.3 3 0 0 3 3 1 0 Helicase HerA, central domain Enkurin PF13864.6 CBZ33663.1 - 4.3e-18 65.5 6.4 7.1e-18 64.9 6.4 1.4 1 0 0 1 1 1 1 Calmodulin-binding GPS2_interact PF15784.5 CBZ33663.1 - 1.2 9.7 5.6 0.57 10.7 2.3 2.1 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain BCDHK_Adom3 PF10436.9 CBZ33664.1 - 1.6e-19 70.3 0.1 2.6e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBZ33664.1 - 1.5e-09 38.3 0.0 3.4e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBZ33664.1 - 3.8e-05 23.5 0.0 8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ZZ PF00569.17 CBZ33665.1 - 7.2e-07 28.9 8.7 7.2e-07 28.9 8.7 2.9 2 0 0 2 2 2 1 Zinc finger, ZZ type C1_2 PF03107.16 CBZ33665.1 - 0.027 14.8 0.4 0.027 14.8 0.4 2.7 2 0 0 2 2 2 0 C1 domain zinc-ribbons_6 PF07191.12 CBZ33665.1 - 8.9 6.4 16.2 0.83 9.7 3.8 2.8 3 0 0 3 3 3 0 zinc-ribbons LRR_6 PF13516.6 CBZ33666.1 - 0.00036 20.4 0.6 0.33 11.1 0.0 3.6 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 CBZ33666.1 - 0.067 13.7 0.8 33 5.1 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ33668.1 - 1e-08 34.8 3.2 8.5e-06 25.5 1.0 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBZ33668.1 - 2.8e-07 30.8 3.0 9.9e-05 22.6 0.4 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ33668.1 - 5.2e-05 23.2 1.2 1.8 9.4 0.1 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 CBZ33668.1 - 0.015 15.3 3.4 34 4.9 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Acetyltransf_13 PF13880.6 CBZ33672.1 - 1.5e-21 76.1 0.0 3e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.7 CBZ33672.1 - 0.058 13.8 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 CBZ33673.1 - 1.8e-17 63.3 33.3 1.1e-13 50.8 6.8 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ33673.1 - 0.00028 19.9 34.1 0.016 14.1 2.0 3.0 2 1 1 3 3 3 3 Sugar (and other) transporter SPC12 PF06645.13 CBZ33673.1 - 3.6 7.8 9.9 5 7.3 0.1 3.2 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MH1 PF03165.16 CBZ33674.1 - 0.12 12.6 0.3 0.4 10.9 0.1 2.0 1 1 1 2 2 2 0 MH1 domain CAP_N PF01213.19 CBZ33674.1 - 9.7 5.6 6.8 0.72 9.3 1.1 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF2946 PF11162.8 CBZ33675.1 - 1e-12 48.7 0.3 3.4e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2946) Vpu PF00558.19 CBZ33675.1 - 0.0021 17.8 0.7 0.0044 16.8 0.7 1.4 1 0 0 1 1 1 1 Vpu protein DUF4381 PF14316.6 CBZ33675.1 - 0.0028 17.9 0.0 0.017 15.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) TMEM174 PF15029.6 CBZ33675.1 - 0.0089 15.8 0.2 0.014 15.1 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 174 ECSCR PF15820.5 CBZ33675.1 - 0.015 15.1 0.2 0.027 14.3 0.2 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator EphA2_TM PF14575.6 CBZ33675.1 - 0.022 15.7 0.0 0.075 13.9 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MAP17 PF15807.5 CBZ33675.1 - 0.028 14.7 0.1 0.05 13.8 0.1 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Shisa PF13908.6 CBZ33675.1 - 0.03 14.6 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4692 PF15763.5 CBZ33675.1 - 0.095 13.2 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Sigma_reg_N PF13800.6 CBZ33675.1 - 0.097 13.0 0.1 0.35 11.2 0.1 1.9 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TMIE PF16038.5 CBZ33675.1 - 0.1 12.5 1.1 0.17 11.8 1.1 1.3 1 0 0 1 1 1 0 TMIE protein Cadherin_C_2 PF16492.5 CBZ33675.1 - 0.15 12.8 0.0 0.68 10.7 0.0 1.9 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal TMEM154 PF15102.6 CBZ33675.1 - 0.17 11.8 0.1 0.28 11.1 0.1 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF3827 PF12877.7 CBZ33675.1 - 0.4 9.0 1.3 0.57 8.5 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) NUDIX PF00293.28 CBZ33678.1 - 0.044 13.8 4.0 6.7 6.8 1.6 3.6 3 1 0 3 3 3 0 NUDIX domain Rad1 PF02144.16 CBZ33679.1 - 1.2e-05 24.6 0.0 0.011 14.8 0.0 2.1 2 0 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Methyltransf_8 PF05148.15 CBZ33682.1 - 1.7e-53 181.7 0.0 2.2e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CBZ33682.1 - 8.5e-07 29.5 0.1 8.9e-06 26.3 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ33682.1 - 0.00023 21.8 0.1 0.063 14.0 0.1 2.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ33682.1 - 0.0081 15.5 0.0 0.032 13.6 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family IHABP4_N PF16174.5 CBZ33682.1 - 1.1 9.9 9.0 1.7 9.2 9.0 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DAO PF01266.24 CBZ33683.1 - 2.1e-16 60.5 1.3 1.5e-13 51.0 1.3 4.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CBZ33683.1 - 2.8e-09 36.9 0.1 5.9e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CBZ33683.1 - 3e-07 29.9 0.3 6.2e-07 28.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CBZ33683.1 - 5.6e-07 29.3 0.4 8.6e-07 28.6 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ33683.1 - 5e-06 26.7 0.6 1.3e-05 25.4 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CBZ33683.1 - 1.7e-05 24.1 0.8 5.5e-05 22.4 0.0 2.1 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.14 CBZ33683.1 - 0.00037 19.3 0.3 0.00057 18.7 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.14 CBZ33683.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ33683.1 - 1.2 9.8 4.2 0.47 11.1 0.3 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GGACT PF06094.12 CBZ33684.1 - 6e-10 39.8 0.0 5.9e-07 30.1 0.0 2.7 2 1 0 2 2 2 2 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 CBZ33684.1 - 2.6e-08 34.2 0.1 9.8e-08 32.3 0.1 2.1 1 0 0 1 1 1 1 AIG2-like family TM231 PF10149.9 CBZ33686.1 - 1.3e-25 90.3 3.3 5.9e-15 55.4 0.0 2.2 2 0 0 2 2 2 2 Transmembrane protein 231 EF-hand_1 PF00036.32 CBZ33686.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 EF hand Tubulin PF00091.25 CBZ33687.1 - 8.1e-27 94.7 0.0 1.3e-13 51.6 0.0 2.9 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 CBZ33687.1 - 0.0027 16.9 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin like PPR_2 PF13041.6 CBZ33688.1 - 4e-12 46.1 0.1 0.0018 18.4 0.0 4.6 3 1 2 5 5 5 4 PPR repeat family PPR PF01535.20 CBZ33688.1 - 2.3e-08 33.7 0.1 0.064 13.5 0.1 4.0 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 CBZ33688.1 - 1.6e-05 24.4 1.2 0.005 16.2 0.2 2.0 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CBZ33688.1 - 5.3e-05 23.2 0.0 0.00084 19.4 0.0 2.6 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 CBZ33688.1 - 0.016 14.9 0.0 0.93 9.3 0.0 2.8 2 0 0 2 2 2 0 PPR repeat A2L_zn_ribbon PF08792.10 CBZ33689.1 - 0.029 14.1 0.4 0.029 14.1 0.4 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc_ribbon_10 PF10058.9 CBZ33689.1 - 0.049 13.4 0.0 8.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein PhnA_Zn_Ribbon PF08274.12 CBZ33689.1 - 0.13 12.3 1.2 12 5.9 0.0 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon CTP_transf_like PF01467.26 CBZ33690.1 - 5.2e-06 26.7 0.0 0.0017 18.5 0.0 2.5 2 0 0 2 2 2 2 Cytidylyltransferase-like Ribosomal_S15 PF00312.22 CBZ33691.1 - 2.9e-07 30.6 1.6 6.3e-07 29.5 1.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 DUF4404 PF14357.6 CBZ33691.1 - 0.16 12.6 1.0 2 9.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) MORN PF02493.20 CBZ33692.1 - 1.2e-19 69.0 13.9 1e-06 28.3 0.1 6.6 6 0 0 6 6 6 4 MORN repeat WW PF00397.26 CBZ33692.1 - 0.013 15.6 0.1 0.034 14.2 0.1 1.7 1 0 0 1 1 1 0 WW domain DivIC PF04977.15 CBZ33692.1 - 3 7.7 7.8 2.7 7.8 5.9 1.9 1 1 0 1 1 1 0 Septum formation initiator Endonuc_Holl PF10107.9 CBZ33693.1 - 0.052 13.4 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase RWD PF05773.22 CBZ33694.1 - 3.8e-10 40.1 0.3 6.1e-10 39.4 0.3 1.3 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 CBZ33694.1 - 1.8e-05 25.1 1.8 3.3e-05 24.3 1.8 1.4 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 phage_tail_N PF08400.10 CBZ33694.1 - 0.1 12.6 1.5 0.37 10.8 0.3 2.3 2 1 1 3 3 3 0 Prophage tail fibre N-terminal DnaJ_C PF01556.18 CBZ33695.1 - 6.4e-18 65.3 0.0 9.5e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CBZ33695.1 - 5.8e-09 36.2 9.8 1.3e-08 35.1 9.8 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ33695.1 - 0.0002 21.2 8.5 0.14 12.2 2.0 2.9 2 1 1 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein Rhv PF00073.20 CBZ33695.1 - 0.15 11.6 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 picornavirus capsid protein Wbp11 PF09429.10 CBZ33695.1 - 0.24 11.8 2.1 0.39 11.1 2.1 1.3 1 0 0 1 1 1 0 WW domain binding protein 11 CTP_synth_N PF06418.14 CBZ33696.1 - 1.3e-106 355.8 0.0 1.7e-106 355.4 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CBZ33696.1 - 4.8e-45 153.7 0.0 1.6e-44 152.0 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CBZ33696.1 - 1.3e-07 31.6 0.1 7.5e-07 29.1 0.1 2.2 2 1 0 2 2 2 1 Peptidase C26 CbiA PF01656.23 CBZ33696.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MORN PF02493.20 CBZ33698.1 - 2.4e-27 93.1 32.5 4.2e-07 29.5 0.4 6.6 6 0 0 6 6 6 6 MORN repeat NTP_transf_2 PF01909.23 CBZ33700.1 - 0.0021 18.3 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Kinesin PF00225.23 CBZ33703.1 - 1.1e-79 267.7 1.4 1.2e-72 244.6 0.0 3.2 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ33703.1 - 6.1e-09 36.0 0.3 0.003 17.5 0.0 2.7 2 0 0 2 2 2 2 Microtubule binding Fib_alpha PF08702.10 CBZ33703.1 - 0.059 13.5 8.1 11 6.2 0.0 3.7 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 CBZ33703.1 - 1.5 8.8 32.0 0.018 15.1 3.0 4.1 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF2353 PF09789.9 CBZ33703.1 - 1.9 7.8 13.8 0.021 14.2 2.8 2.5 2 0 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Rnk_N PF14760.6 CBZ33703.1 - 4.8 7.8 6.2 8 7.0 2.0 2.9 2 0 0 2 2 2 0 Rnk N-terminus CLZ PF16526.5 CBZ33703.1 - 5.7 7.4 9.0 1.7 9.1 0.3 3.7 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 CBZ33703.1 - 8.3 7.0 33.5 0.031 14.8 7.5 4.4 3 1 1 4 4 4 0 Apg6 coiled-coil region Snapin_Pallidin PF14712.6 CBZ33703.1 - 9.7 6.7 16.5 1.2 9.6 0.2 4.6 3 1 2 5 5 5 0 Snapin/Pallidin TPR_14 PF13428.6 CBZ33704.1 - 1.6e-05 25.3 8.2 7.1 7.7 0.1 6.4 3 1 4 7 7 7 2 Tetratricopeptide repeat Suf PF05843.14 CBZ33704.1 - 0.031 14.3 4.5 1.4 8.8 0.1 3.3 2 2 0 2 2 2 0 Suppressor of forked protein (Suf) Bacteriocin_II PF01721.18 CBZ33704.1 - 0.097 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Class II bacteriocin TPR_2 PF07719.17 CBZ33704.1 - 0.3 11.3 3.6 46 4.5 0.2 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Adeno_PIX PF03955.14 CBZ33704.1 - 1.5 9.0 6.3 2.7 8.2 0.1 2.9 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) HEAT PF02985.22 CBZ33705.1 - 7.3e-25 84.9 45.6 0.0033 17.6 0.1 13.8 15 0 0 15 15 15 8 HEAT repeat HEAT_2 PF13646.6 CBZ33705.1 - 4.3e-24 84.7 24.2 2.3e-07 31.1 0.1 8.2 2 2 6 8 8 8 7 HEAT repeats HEAT_EZ PF13513.6 CBZ33705.1 - 3.8e-08 33.7 25.4 0.0042 17.6 0.0 8.5 5 3 5 10 10 10 4 HEAT-like repeat Cnd1 PF12717.7 CBZ33705.1 - 2.5e-07 30.9 9.3 0.016 15.3 0.1 5.6 1 1 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CBZ33705.1 - 2.7e-06 27.9 0.3 0.0096 16.5 0.0 5.4 2 1 3 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CBZ33705.1 - 6.4e-05 21.7 7.9 0.037 12.6 1.0 3.4 1 1 1 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.8 CBZ33705.1 - 8.3e-05 22.3 2.0 0.055 13.0 0.3 3.9 1 1 3 5 5 5 1 CLASP N terminal TAF6_C PF07571.13 CBZ33705.1 - 0.15 12.4 0.2 5.6 7.4 0.1 3.4 2 1 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Acyl-CoA_dh_C PF12806.7 CBZ33706.1 - 0.00074 19.7 0.5 0.0013 18.9 0.5 1.4 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Tfb2 PF03849.14 CBZ33706.1 - 0.0091 15.0 1.4 0.012 14.6 1.4 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 DUF775 PF05603.12 CBZ33707.1 - 6.1e-19 68.3 0.0 1.2e-18 67.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF775) Rtt106_N PF18215.1 CBZ33707.1 - 0.16 11.7 0.1 0.87 9.4 0.0 2.2 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain DUF4422 PF14393.6 CBZ33708.1 - 0.048 13.5 6.2 4.7 7.0 6.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4422) TGF_beta_GS PF08515.12 CBZ33710.1 - 1.2 8.7 7.4 4.6 6.8 0.6 3.0 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Pkinase PF00069.25 CBZ33711.1 - 3.4e-56 190.5 0.0 5.2e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33711.1 - 2.4e-36 125.4 0.0 3.7e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 CBZ33711.1 - 1.5e-14 53.8 0.3 6.8e-07 29.3 0.1 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain PAS PF00989.25 CBZ33711.1 - 9.9e-06 25.5 0.0 3.2e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CBZ33711.1 - 0.00012 22.3 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 PAS domain Kinase-like PF14531.6 CBZ33711.1 - 0.001 18.5 0.0 0.0081 15.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like PAS_4 PF08448.10 CBZ33711.1 - 0.0023 18.2 0.1 0.012 15.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 CBZ33711.1 - 0.049 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold Tubulin_3 PF14881.6 CBZ33712.1 - 7.5e-06 25.7 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CBZ33712.1 - 0.0051 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain TTL PF03133.15 CBZ33713.1 - 5.8e-47 160.2 0.0 9.3e-38 130.0 0.0 2.4 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family Snf7 PF03357.21 CBZ33714.1 - 0.0056 16.3 1.2 0.0056 16.3 1.2 4.2 2 1 2 4 4 4 2 Snf7 CNDH2_C PF16858.5 CBZ33714.1 - 8 6.2 24.9 0.013 15.4 10.2 2.3 2 1 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term AAA PF00004.29 CBZ33715.1 - 1.2e-48 164.9 0.0 1.8e-36 125.5 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ33715.1 - 2.2e-09 37.0 0.0 5.6e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CBZ33715.1 - 4.2e-09 36.8 0.9 0.057 13.7 0.0 4.4 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 CBZ33715.1 - 1.1e-07 32.4 0.1 0.0088 16.4 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 CBZ33715.1 - 1.8e-07 31.7 0.1 0.023 15.2 0.0 3.0 3 1 0 3 3 2 2 AAA domain AAA_5 PF07728.14 CBZ33715.1 - 1.9e-07 31.1 0.0 0.0027 17.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CBZ33715.1 - 4.1e-06 26.2 0.0 0.027 13.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Mg_chelatase PF01078.21 CBZ33715.1 - 1.9e-05 24.2 0.0 0.0029 17.0 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CBZ33715.1 - 5.7e-05 22.9 0.0 0.036 13.8 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CBZ33715.1 - 0.00025 21.4 0.0 0.23 11.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 CBZ33715.1 - 0.00033 20.6 0.1 0.36 10.7 0.0 3.7 3 1 0 3 3 3 1 NACHT domain AAA_7 PF12775.7 CBZ33715.1 - 0.00038 20.0 0.0 0.0056 16.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 CBZ33715.1 - 0.00045 20.1 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBZ33715.1 - 0.00048 19.9 0.0 0.28 10.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 CBZ33715.1 - 0.0006 19.6 0.0 0.59 9.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CBZ33715.1 - 0.00064 19.5 0.0 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 CBZ33715.1 - 0.00066 19.9 0.0 0.91 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CBZ33715.1 - 0.00074 20.0 0.1 0.81 10.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain Sigma54_activ_2 PF14532.6 CBZ33715.1 - 0.00091 19.3 0.0 0.87 9.7 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 CBZ33715.1 - 0.0012 19.2 0.0 2 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 CBZ33715.1 - 0.0035 16.6 0.5 3.9 6.6 0.5 2.9 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) TsaE PF02367.17 CBZ33715.1 - 0.0035 17.3 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 CBZ33715.1 - 0.0036 17.4 0.0 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 CBZ33715.1 - 0.0037 17.0 0.0 0.071 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBZ33715.1 - 0.0044 16.8 0.0 0.63 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBZ33715.1 - 0.0053 17.1 0.5 1.2 9.4 0.1 3.1 4 0 0 4 4 2 1 AAA domain Zeta_toxin PF06414.12 CBZ33715.1 - 0.0057 16.0 0.1 0.34 10.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Cytidylate_kin PF02224.18 CBZ33715.1 - 0.016 14.9 0.0 0.8 9.4 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 CBZ33715.1 - 0.017 15.7 0.7 1.1 9.8 0.0 3.3 3 1 1 4 4 3 0 ABC transporter DUF1599 PF07659.11 CBZ33715.1 - 0.023 15.2 0.1 0.058 13.9 0.1 1.6 1 0 0 1 1 1 0 Nucleotide modification associated domain 1 ATPase PF06745.13 CBZ33715.1 - 0.028 13.8 0.1 1.8 7.8 0.1 2.5 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 CBZ33715.1 - 0.028 14.4 0.0 9.8 6.1 0.0 3.2 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_25 PF13481.6 CBZ33715.1 - 0.034 13.7 0.3 3.3 7.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 CBZ33715.1 - 0.041 13.8 0.1 8 6.3 0.1 3.0 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 CBZ33715.1 - 0.048 12.7 0.0 7 5.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 CBZ33715.1 - 0.051 13.0 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein KTI12 PF08433.10 CBZ33715.1 - 0.055 12.9 0.1 9.7 5.5 0.0 2.7 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 CBZ33715.1 - 0.066 13.0 0.3 7.5 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.22 CBZ33715.1 - 0.072 12.3 0.0 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain CPT PF07931.12 CBZ33715.1 - 0.1 12.4 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sec16_C PF12931.7 CBZ33716.1 - 0.04 13.6 0.0 0.055 13.1 0.0 1.1 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 ACPS PF01648.20 CBZ33717.1 - 2e-12 47.2 0.0 3.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily SCO1-SenC PF02630.14 CBZ33718.1 - 2e-29 102.2 0.1 1.7e-27 95.9 0.1 2.3 1 1 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 CBZ33718.1 - 0.016 15.5 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like TruD PF01142.18 CBZ33719.1 - 7.9e-12 44.7 0.0 2.8e-07 29.7 0.0 3.2 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) DEAD PF00270.29 CBZ33721.1 - 3.6e-30 105.0 0.1 3.2e-16 59.6 0.0 2.6 2 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ33721.1 - 4.9e-16 59.1 0.0 1.5e-15 57.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ33721.1 - 4.4e-07 30.1 0.0 2.3e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ33721.1 - 0.045 14.0 0.2 7.8 6.8 0.1 2.7 2 0 0 2 2 2 0 AAA domain Scramblase PF03803.15 CBZ33721.1 - 0.13 11.5 0.3 0.24 10.6 0.3 1.3 1 0 0 1 1 1 0 Scramblase Elf1 PF05129.13 CBZ33722.1 - 1.1e-18 67.0 0.4 1.6e-18 66.5 0.4 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Elf1 PF05129.13 CBZ33723.1 - 4.1e-12 46.0 0.2 6.8e-12 45.3 0.2 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribonuclease_3 PF00636.26 CBZ33724.1 - 4.6e-06 27.2 0.0 1.4e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain DUF4379 PF14311.6 CBZ33729.1 - 6.3e-17 61.7 10.4 4.2e-10 39.8 7.3 2.6 2 0 0 2 2 2 2 Probable Zinc-ribbon domain Cytochrom_C1 PF02167.15 CBZ33729.1 - 0.13 11.9 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C1 family Pkinase PF00069.25 CBZ33730.1 - 1e-47 162.7 0.0 2.5e-30 105.7 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33730.1 - 1.4e-29 103.2 0.0 2.5e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ33730.1 - 6.6e-05 21.9 0.2 0.0003 19.7 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase PAS_8 PF13188.7 CBZ33730.1 - 0.045 13.8 0.0 0.28 11.3 0.0 2.3 2 0 0 2 2 2 0 PAS domain Kinase-like PF14531.6 CBZ33730.1 - 0.049 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ARD PF03079.14 CBZ33731.1 - 8.9e-37 126.7 0.0 1.3e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family DUF953 PF06110.11 CBZ33731.1 - 4.6e-15 55.3 0.0 7.6e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Cupin_2 PF07883.11 CBZ33731.1 - 3.3e-09 36.3 0.0 5.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CBZ33731.1 - 1.8e-06 27.9 0.1 1.9e-05 24.6 0.0 2.4 3 0 0 3 3 3 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CBZ33731.1 - 0.02 14.5 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Cupin Tox-HDC PF15656.6 CBZ33731.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Toxin with a H, D/N and C signature Ebp2 PF05890.12 CBZ33732.1 - 2.6e-46 158.3 13.6 3.8e-46 157.8 13.6 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Lysine_decarbox PF03641.14 CBZ33733.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Possible lysine decarboxylase Glutaredoxin PF00462.24 CBZ33737.1 - 1e-11 44.8 0.0 1.5e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CBZ33737.1 - 0.048 13.7 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain SH3BGR PF04908.15 CBZ33737.1 - 0.081 13.1 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein GST_N_3 PF13417.6 CBZ33737.1 - 0.086 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain BetaGal_dom4_5 PF13364.6 CBZ33737.1 - 0.11 13.1 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain zf-RING_2 PF13639.6 CBZ33745.1 - 0.001 19.4 3.3 0.001 19.4 3.3 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CBZ33745.1 - 0.0052 17.0 12.0 0.015 15.6 12.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBZ33745.1 - 0.0086 15.9 2.3 0.021 14.7 2.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) oligo_HPY PF08352.12 CBZ33745.1 - 0.035 14.6 0.1 4.4 7.9 0.0 3.0 2 0 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region Zn_ribbon_17 PF17120.5 CBZ33745.1 - 0.1 12.2 13.0 0.0069 16.0 7.2 2.1 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CBZ33745.1 - 1.2 9.1 9.2 5.8 7.0 9.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain AAA PF00004.29 CBZ33746.1 - 0.0046 17.4 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CBZ33746.1 - 0.019 14.0 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 CBZ33746.1 - 0.045 14.0 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBZ33746.1 - 0.22 11.4 0.0 0.41 10.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 CBZ33746.1 - 5.5 7.3 7.9 0.55 10.6 0.1 3.3 4 0 0 4 4 4 0 AAA ATPase domain MORN PF02493.20 CBZ33747.1 - 1.3e-11 43.6 14.7 0.00042 20.0 1.1 4.6 4 0 0 4 4 4 3 MORN repeat PI3_PI4_kinase PF00454.27 CBZ33749.1 - 1.1e-46 159.7 0.0 2.2e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CBZ33749.1 - 2.2e-30 106.0 1.3 4.2e-30 105.1 1.3 1.5 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 CBZ33749.1 - 4.1e-09 36.1 0.0 1.4e-08 34.4 0.0 2.0 1 0 0 1 1 1 1 FATC domain TFCD_C PF12612.8 CBZ33749.1 - 0.00014 21.8 1.9 0.00069 19.5 0.1 3.3 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 CBZ33749.1 - 0.0006 19.9 0.2 8.6 6.9 0.0 6.0 7 0 0 7 7 7 1 HEAT repeat TIP120 PF08623.10 CBZ33749.1 - 0.17 11.6 0.6 32 4.3 0.0 3.1 2 1 0 2 2 2 0 TATA-binding protein interacting (TIP20) DnaJ PF00226.31 CBZ33750.1 - 4.9e-18 65.0 0.5 4.9e-18 65.0 0.5 2.3 2 0 0 2 2 2 1 DnaJ domain Myb_DNA-bind_6 PF13921.6 CBZ33750.1 - 0.00037 20.7 2.3 0.053 13.8 0.9 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CBZ33750.1 - 0.00043 20.4 11.8 0.0019 18.4 0.3 3.9 4 0 0 4 4 4 2 Myb-like DNA-binding domain TFB6 PF17110.5 CBZ33750.1 - 5.3 6.8 8.3 22 4.7 8.3 2.0 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH YIF1 PF03878.15 CBZ33751.1 - 1.1e-43 149.5 0.0 2.3e-43 148.5 0.0 1.4 1 1 0 1 1 1 1 YIF1 Yip1 PF04893.17 CBZ33751.1 - 6.6e-05 22.7 14.4 0.00015 21.6 14.4 1.5 1 0 0 1 1 1 1 Yip1 domain PRP38 PF03371.15 CBZ33752.1 - 9.4e-13 48.4 0.0 1.4e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 PRP38 family Esterase PF00756.20 CBZ33754.1 - 6.4e-15 55.5 0.0 7.4e-14 52.0 0.0 2.1 1 1 0 1 1 1 1 Putative esterase CBM_48 PF02922.18 CBZ33754.1 - 0.016 15.6 0.0 0.054 13.9 0.0 1.9 1 1 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Peptidase_C2 PF00648.21 CBZ33758.1 - 2.9e-55 187.4 0.0 5.3e-55 186.5 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ33758.1 - 8.7e-33 112.8 0.1 1.8e-32 111.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CBZ33759.1 - 8.7e-46 156.3 0.0 1.2e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ33759.1 - 5.8e-25 87.7 0.0 1.1e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CBZ33760.1 - 3.1e-35 121.6 0.0 5.7e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ33760.1 - 2.5e-09 37.4 0.0 8.9e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ33761.1 - 6.2e-25 87.6 0.0 7.4e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ33762.1 - 1.7e-27 95.8 0.0 2.1e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Raptor_N PF14538.6 CBZ33763.1 - 3.1e-10 40.2 0.0 6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain DUF1935 PF09149.10 CBZ33764.1 - 1.5e-30 105.6 0.0 2.5e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ33765.1 - 0.0099 16.2 0.0 4.4 7.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ33766.1 - 3.5e-06 27.3 0.0 4.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Cupredoxin_1 PF13473.6 CBZ33766.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Cupredoxin-like domain DUF1935 PF09149.10 CBZ33767.1 - 8.6e-31 106.4 0.0 1.2e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) NAP PF00956.18 CBZ33768.1 - 4.8e-12 45.6 1.0 5.8e-08 32.3 0.0 2.1 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) DUF1935 PF09149.10 CBZ33769.1 - 6.3e-35 119.7 0.1 7.3e-35 119.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ33770.1 - 2.2e-39 134.0 0.4 2.6e-39 133.8 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) TraS PF10624.9 CBZ33770.1 - 0.087 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Thioredoxin_8 PF13905.6 CBZ33771.1 - 0.00015 22.0 0.0 0.00032 21.0 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like LPD39 PF18858.1 CBZ33771.1 - 0.079 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 39 Pkinase PF00069.25 CBZ33772.1 - 1.1e-33 116.8 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33772.1 - 1.1e-18 67.5 0.0 1.8e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ33772.1 - 0.00033 20.1 0.1 0.07 12.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CBZ33772.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ33772.1 - 0.051 13.5 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adaptin_N PF01602.20 CBZ33774.1 - 5.3e-64 216.7 6.7 7.3e-64 216.2 6.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 CBZ33774.1 - 9.8e-48 161.4 0.0 2.2e-47 160.2 0.0 1.6 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CBZ33774.1 - 3e-42 143.8 0.0 7.7e-42 142.5 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 CBZ33774.1 - 4.4e-07 30.2 6.6 0.37 11.2 0.0 6.0 6 2 0 6 6 6 3 HEAT repeats HEAT PF02985.22 CBZ33774.1 - 9.4e-07 28.6 2.6 0.67 10.4 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 CBZ33774.1 - 2.6e-05 24.3 4.8 0.00048 20.2 0.1 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF4147 PF13660.6 CBZ33774.1 - 0.06 12.9 0.6 1.6 8.3 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) DUF5471 PF17565.2 CBZ33774.1 - 0.079 13.3 0.1 0.22 11.8 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5471) HEAT_EZ PF13513.6 CBZ33774.1 - 2 9.0 5.2 62 4.2 0.0 5.0 6 0 0 6 6 6 0 HEAT-like repeat RNase_PH PF01138.21 CBZ33775.1 - 0.083 13.4 0.0 0.39 11.2 0.0 2.0 2 0 0 2 2 2 0 3' exoribonuclease family, domain 1 PUF PF00806.19 CBZ33776.1 - 4e-18 64.0 0.0 0.0025 17.4 0.0 4.4 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat ANAPC4_WD40 PF12894.7 CBZ33778.1 - 0.085 13.2 0.0 0.97 9.8 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Tropomyosin_1 PF12718.7 CBZ33779.1 - 0.0095 16.1 5.7 1.1 9.4 0.1 3.1 3 0 0 3 3 3 2 Tropomyosin like BRE1 PF08647.11 CBZ33779.1 - 0.035 14.2 2.1 1.8 8.7 0.2 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Trimer_CC PF08954.11 CBZ33779.1 - 0.045 13.3 20.2 0.09 12.3 0.9 4.5 4 0 0 4 4 4 0 Trimerisation motif CENP-F_leu_zip PF10473.9 CBZ33779.1 - 0.085 12.9 9.8 0.38 10.8 0.1 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 CBZ33779.1 - 0.13 12.5 5.6 3.4 7.9 0.2 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Striatin PF08232.12 CBZ33779.1 - 0.17 12.5 17.5 0.044 14.4 1.9 3.4 2 1 1 3 3 3 0 Striatin family DivIC PF04977.15 CBZ33779.1 - 0.36 10.6 14.0 0.044 13.5 1.2 3.3 3 0 0 3 3 3 0 Septum formation initiator Prefoldin_2 PF01920.20 CBZ33779.1 - 0.45 10.5 5.1 7.6 6.5 0.9 2.9 3 0 0 3 3 3 0 Prefoldin subunit Spc24 PF08286.11 CBZ33779.1 - 0.82 9.9 9.1 4 7.7 0.3 3.4 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 Sipho_Gp157 PF05565.11 CBZ33779.1 - 2.5 8.1 7.3 0.88 9.6 0.4 2.8 3 0 0 3 3 3 0 Siphovirus Gp157 Arm PF00514.23 CBZ33780.1 - 4.5e-33 112.3 19.2 8.1e-07 28.9 0.0 8.9 9 0 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CBZ33780.1 - 2.7e-17 61.4 10.9 0.029 14.6 0.1 8.0 8 0 0 8 8 7 4 HEAT repeat HEAT_2 PF13646.6 CBZ33780.1 - 6.8e-16 58.4 16.6 0.00022 21.6 0.1 5.4 2 2 5 7 7 7 6 HEAT repeats HEAT_EZ PF13513.6 CBZ33780.1 - 8.4e-14 51.7 18.2 0.015 15.8 0.3 6.4 6 1 1 7 7 7 5 HEAT-like repeat Cnd1 PF12717.7 CBZ33780.1 - 1.2e-12 48.2 0.1 0.0016 18.5 0.0 3.6 2 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBZ33780.1 - 4.1e-11 42.2 1.2 3.1e-08 32.6 1.5 3.1 2 1 1 3 3 3 2 Adaptin N terminal region DNA_alkylation PF08713.11 CBZ33780.1 - 9.2e-09 35.3 0.1 0.0071 16.1 0.0 4.1 2 1 1 4 4 4 3 DNA alkylation repair enzyme CLASP_N PF12348.8 CBZ33780.1 - 3.8e-05 23.4 0.6 0.33 10.5 0.0 3.0 1 1 1 2 2 2 2 CLASP N terminal V-ATPase_H_C PF11698.8 CBZ33780.1 - 0.00026 21.1 0.6 0.34 11.0 0.3 4.0 3 2 1 4 4 4 2 V-ATPase subunit H CHASE6_C PF17150.4 CBZ33780.1 - 0.00065 20.3 3.1 14 6.4 0.0 5.5 5 1 0 6 6 6 0 C-terminal domain of two-partite extracellular sensor domain Mo25 PF08569.11 CBZ33780.1 - 0.00074 19.0 0.1 0.32 10.3 0.1 2.4 1 1 0 2 2 2 2 Mo25-like RICTOR_N PF14664.6 CBZ33780.1 - 0.0015 17.6 0.3 0.064 12.2 0.1 2.9 1 1 1 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term Proteasom_PSMB PF10508.9 CBZ33780.1 - 0.0052 15.4 2.7 0.52 8.7 0.6 2.8 1 1 1 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_UF PF18817.1 CBZ33780.1 - 0.0057 16.9 0.0 0.31 11.4 0.0 3.5 3 0 0 3 3 3 1 Repeat of uncharacterized protein PH0542 HEAT_PBS PF03130.16 CBZ33780.1 - 0.01 16.4 15.3 0.82 10.5 2.2 6.2 6 1 0 6 6 5 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 CBZ33780.1 - 0.012 16.1 0.1 0.7 10.5 0.0 3.4 1 1 3 4 4 4 0 Vacuolar 14 Fab1-binding region DUF3361 PF11841.8 CBZ33780.1 - 0.047 13.6 0.2 4.8 7.1 0.1 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) SET PF00856.28 CBZ33783.1 - 0.033 14.6 0.0 0.043 14.2 0.0 1.2 1 0 0 1 1 1 0 SET domain GABP-alpha PF11620.8 CBZ33785.1 - 0.07 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 GA-binding protein alpha chain PUMA PF15826.5 CBZ33786.1 - 0.00074 19.8 1.8 0.004 17.3 2.3 1.7 2 0 0 2 2 2 1 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis C2 PF00168.30 CBZ33786.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 C2 domain Myotub-related PF06602.14 CBZ33788.1 - 5.8e-91 305.1 0.0 1.8e-90 303.4 0.0 1.8 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 CBZ33788.1 - 0.0066 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family FYVE_2 PF02318.16 CBZ33788.1 - 0.21 11.8 8.2 0.56 10.4 8.2 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger FYVE PF01363.21 CBZ33788.1 - 0.33 11.1 11.6 1 9.6 11.6 1.8 1 0 0 1 1 1 0 FYVE zinc finger C1_4 PF07975.12 CBZ33788.1 - 1.6 9.1 12.0 7.4 6.9 12.0 2.2 1 0 0 1 1 1 0 TFIIH C1-like domain HEAT PF02985.22 CBZ33789.1 - 0.012 15.8 0.7 1.2 9.6 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat RCDG1 PF15725.5 CBZ33791.1 - 0.6 10.6 7.8 0.55 10.7 4.0 3.0 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein DUF4456 PF14644.6 CBZ33792.1 - 5.6e-11 42.5 0.0 5.6e-11 42.5 0.0 4.8 6 0 0 6 6 6 1 Domain of unknown function (DUF4456) DUF4455 PF14643.6 CBZ33792.1 - 9.5e-07 27.8 0.1 9.5e-07 27.8 0.1 4.8 4 1 0 4 4 4 2 Domain of unknown function (DUF4455) Phage_GP20 PF06810.11 CBZ33792.1 - 3 7.6 6.0 0.99 9.2 2.0 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 AAA PF00004.29 CBZ33793.1 - 5.6e-26 91.5 0.0 3.5e-25 88.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ33793.1 - 0.00098 19.4 0.1 0.019 15.3 0.1 2.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CBZ33793.1 - 0.0017 18.8 0.0 0.0044 17.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CBZ33793.1 - 0.0027 18.1 1.1 0.0027 18.1 1.1 3.8 2 2 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 CBZ33793.1 - 0.04 13.1 0.0 0.066 12.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_29 PF13555.6 CBZ33793.1 - 0.058 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 CBZ33793.1 - 0.068 13.3 0.3 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CBZ33793.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CBZ33793.1 - 0.12 13.0 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ33793.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CBZ33793.1 - 0.21 11.5 0.0 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF1534 PF07551.11 CBZ33793.1 - 0.22 11.3 3.0 6.9 6.5 1.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1534) AAA_23 PF13476.6 CBZ33793.1 - 0.32 11.5 0.0 0.7 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ33793.1 - 0.47 10.4 3.6 2.9 7.8 0.1 3.3 3 1 0 3 3 3 0 NACHT domain RVT_1 PF00078.27 CBZ33794.1 - 0.099 12.1 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.18 CBZ33795.1 - 1.9e-15 57.1 0.1 2.8e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SGS PF05002.15 CBZ33796.1 - 7e-32 109.4 0.6 1.2e-31 108.7 0.6 1.4 1 0 0 1 1 1 1 SGS domain CS PF04969.16 CBZ33796.1 - 5.7e-06 27.3 0.0 1.4e-05 26.1 0.0 1.6 2 0 0 2 2 2 1 CS domain DnaB_2 PF07261.11 CBZ33797.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Replication initiation and membrane attachment KleE PF17394.2 CBZ33797.1 - 1 9.6 3.5 0.66 10.2 1.0 2.0 2 0 0 2 2 2 0 Uncharacterized KleE stable inheritance protein Brix PF04427.18 CBZ33798.1 - 9.6e-34 117.2 0.0 1.4e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain Ribosomal_60s PF00428.19 CBZ33798.1 - 9.7 6.9 9.3 1.5e+02 3.1 0.0 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_C50 PF03568.17 CBZ33799.1 - 9.1e-38 130.4 0.3 5.8e-32 111.3 0.3 2.8 2 1 0 2 2 2 2 Peptidase family C50 CHAT PF12770.7 CBZ33799.1 - 9.8e-10 38.3 1.9 2.8e-05 23.7 0.1 2.9 3 0 0 3 3 3 2 CHAT domain SNAP PF14938.6 CBZ33800.1 - 4.7e-56 190.3 13.5 5.4e-56 190.1 13.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CBZ33800.1 - 2.3e-06 27.8 8.4 5.8e-05 23.3 1.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat BAR PF03114.18 CBZ33800.1 - 0.019 14.6 0.9 0.053 13.2 0.2 2.1 2 0 0 2 2 2 0 BAR domain TPR_5 PF12688.7 CBZ33800.1 - 0.026 14.8 0.2 5.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Tetratrico peptide repeat DUF3741 PF12552.8 CBZ33800.1 - 0.082 12.9 0.9 0.61 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) DUF1033 PF06279.11 CBZ33800.1 - 0.3 11.3 3.0 0.38 10.9 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) TPR_8 PF13181.6 CBZ33800.1 - 0.55 10.6 9.7 24 5.5 0.3 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ33800.1 - 0.88 10.3 9.7 4.8 7.9 2.1 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ33800.1 - 4 8.3 14.4 80 4.2 0.3 5.6 3 3 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ33800.1 - 5.1 7.5 14.3 11 6.4 0.5 5.4 4 1 0 5 5 5 0 Tetratricopeptide repeat tRNA_U5-meth_tr PF05958.11 CBZ33802.1 - 1.5e-16 60.4 0.0 1.4e-15 57.2 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CBZ33802.1 - 1.9e-10 40.7 0.0 3.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ33802.1 - 2.7e-09 37.6 0.0 8.5e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CBZ33802.1 - 2.3e-06 27.4 0.0 3.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 CBZ33802.1 - 1.6e-05 24.8 0.0 3.1e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 CBZ33802.1 - 3.6e-05 24.3 0.0 0.00018 22.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CBZ33802.1 - 6.7e-05 22.5 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CBZ33802.1 - 0.0001 21.7 0.4 0.00031 20.2 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 CBZ33802.1 - 0.00035 20.2 0.0 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 CBZ33802.1 - 0.0018 17.8 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 CBZ33802.1 - 0.0056 16.1 0.1 0.01 15.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CBZ33802.1 - 0.0096 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 CBZ33802.1 - 0.016 14.9 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) DOT1 PF08123.13 CBZ33802.1 - 0.019 14.5 0.1 0.037 13.5 0.1 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_18 PF12847.7 CBZ33802.1 - 0.028 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RNA_ligase PF09414.10 CBZ33804.1 - 2.1e-23 83.4 0.0 2.9e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 RNA ligase T4_Rnl2_C PF18043.1 CBZ33804.1 - 1.4e-08 34.7 0.0 4e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal Peptidase_M20 PF01546.28 CBZ33806.1 - 0.00014 21.6 0.0 0.00031 20.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.28 CBZ33808.1 - 6.3e-12 45.6 0.1 1.5e-11 44.4 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DUF3819 PF12842.7 CBZ33808.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) PPR_2 PF13041.6 CBZ33809.1 - 1.2e-15 57.4 2.8 3.2e-05 24.0 0.0 5.5 5 0 0 5 5 5 3 PPR repeat family PPR_3 PF13812.6 CBZ33809.1 - 2.7e-14 53.0 0.0 4.3e-05 23.5 0.0 4.5 3 1 0 4 4 4 3 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ33809.1 - 5e-13 48.9 0.7 0.00043 19.7 0.0 3.5 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CBZ33809.1 - 3.2e-05 23.5 0.1 0.59 9.9 0.0 5.0 5 0 0 5 5 5 1 PPR repeat PPR PF01535.20 CBZ33809.1 - 0.00037 20.5 9.2 0.79 10.1 0.9 5.8 7 0 0 7 7 7 2 PPR repeat Pkr1 PF08636.10 CBZ33810.1 - 1.1e-05 25.4 8.9 1.5e-05 25.1 8.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 ANAPC4_WD40 PF12894.7 CBZ33811.1 - 0.026 14.8 0.0 0.75 10.1 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1442 PF07279.11 CBZ33811.1 - 0.035 13.4 0.1 0.07 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) MRP-S32 PF10210.9 CBZ33812.1 - 0.066 13.8 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 CHORD PF04968.12 CBZ33813.1 - 5.8e-39 132.6 32.9 1.2e-19 70.7 11.9 2.3 2 0 0 2 2 2 2 CHORD Tetraspanin PF00335.20 CBZ33813.1 - 0.033 13.9 1.0 0.049 13.3 1.0 1.5 1 0 0 1 1 1 0 Tetraspanin family Methyltransf_12 PF08242.12 CBZ33814.1 - 9.6e-15 55.1 0.2 6.4e-13 49.3 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ33814.1 - 9.1e-13 48.4 0.0 1.4e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ33814.1 - 4.7e-12 46.4 0.1 1.8e-06 28.5 0.0 3.1 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ33814.1 - 3.1e-11 43.3 0.0 4.4e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ33814.1 - 1.6e-09 38.3 0.0 0.00082 20.0 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_24 PF13578.6 CBZ33814.1 - 0.003 18.6 0.0 0.0079 17.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 CBZ33814.1 - 0.0051 16.5 0.0 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 Nodulation protein S (NodS) zf-rbx1 PF12678.7 CBZ33815.1 - 1.4e-24 86.1 15.6 1.9e-24 85.7 15.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ33815.1 - 3.1e-17 62.4 11.5 3.8e-17 62.1 11.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBZ33815.1 - 9.1e-06 25.9 17.9 0.00039 20.7 17.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ33815.1 - 0.0009 19.0 15.5 0.061 13.2 15.5 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ33815.1 - 0.0089 15.9 14.4 0.1 12.5 14.4 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ33815.1 - 0.14 12.2 9.3 0.3 11.1 9.3 1.6 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CBZ33815.1 - 0.64 9.7 16.8 0.083 12.5 4.8 2.2 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CBZ33815.1 - 5.4 7.1 14.6 51 3.9 14.7 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 CBZ33815.1 - 7.8 6.3 17.5 3.7e+02 1.0 17.5 2.5 1 1 0 1 1 1 0 RING-like zinc finger OmpH PF03938.14 CBZ33817.1 - 0.0067 16.8 5.9 0.032 14.6 4.0 2.3 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 CBZ33817.1 - 0.0075 16.3 3.5 1.2 9.1 0.1 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1664) PHM7_cyt PF14703.6 CBZ33817.1 - 0.0081 16.4 2.5 0.013 15.7 2.5 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF4047 PF13256.6 CBZ33817.1 - 0.031 14.5 3.5 0.58 10.4 0.5 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4047) Translat_reg PF01818.17 CBZ33817.1 - 0.038 14.0 0.1 0.1 12.6 0.0 1.7 1 1 0 1 1 1 0 Bacteriophage translational regulator DASH_Duo1 PF08651.10 CBZ33817.1 - 0.055 13.2 1.7 0.94 9.3 0.5 2.6 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF948 PF06103.11 CBZ33817.1 - 0.11 12.7 3.2 35 4.7 0.4 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Tape_meas_lam_C PF09718.10 CBZ33817.1 - 0.12 12.5 0.4 8.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF1043 PF06295.12 CBZ33817.1 - 0.18 11.8 4.8 2.2 8.3 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) DUF5082 PF16888.5 CBZ33817.1 - 0.21 11.9 3.9 1.3 9.4 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) AAA_11 PF13086.6 CBZ33817.1 - 0.77 9.5 5.5 1.5 8.6 5.6 1.5 1 1 0 1 1 1 0 AAA domain PRKG1_interact PF15898.5 CBZ33817.1 - 0.84 10.6 14.4 0.094 13.6 3.0 3.0 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3496 PF12001.8 CBZ33817.1 - 2.5 8.5 10.1 1.8 8.9 5.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3496) Nnf1 PF03980.14 CBZ33817.1 - 3 8.3 6.2 0.56 10.6 1.8 2.1 2 0 0 2 2 2 0 Nnf1 DUF4407 PF14362.6 CBZ33817.1 - 4.1 6.7 7.0 3.4 6.9 4.7 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Gln-synt_C PF00120.24 CBZ33818.1 - 0.0047 16.0 0.6 0.0067 15.5 0.1 1.6 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Halogen_Hydrol PF10112.9 CBZ33818.1 - 0.0099 15.9 0.4 0.19 11.7 0.0 2.3 2 1 0 2 2 2 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein OmpH PF03938.14 CBZ33818.1 - 0.01 16.1 0.1 0.29 11.5 0.2 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HEPN_Apea PF18739.1 CBZ33818.1 - 0.057 13.8 0.3 0.26 11.7 0.1 2.2 1 1 1 2 2 2 0 Apea-like HEPN DUF3546 PF12066.8 CBZ33818.1 - 0.098 12.9 4.4 0.047 13.9 2.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) TMPIT PF07851.13 CBZ33818.1 - 0.13 11.5 4.6 2.1 7.5 0.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein PIN_8 PF18476.1 CBZ33818.1 - 0.38 10.6 5.3 0.55 10.0 2.0 2.3 1 1 0 2 2 2 0 PIN like domain SNARE PF05739.19 CBZ33819.1 - 2e-07 30.9 0.8 5.3e-07 29.5 0.8 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-6_N PF09177.11 CBZ33819.1 - 0.029 14.9 4.2 0.036 14.6 0.6 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TrpBP PF02081.15 CBZ33819.1 - 0.051 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein WD40 PF00400.32 CBZ33821.1 - 5.2e-21 74.6 11.2 1e-07 32.5 0.1 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ33821.1 - 7e-05 23.0 0.2 0.11 12.8 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ33821.1 - 0.00069 18.4 3.8 0.075 11.7 0.2 3.6 2 2 3 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CBZ33821.1 - 0.021 13.6 0.0 9.4 4.9 0.0 3.4 2 2 1 3 3 3 0 Nup133 N terminal like MFS_1 PF07690.16 CBZ33823.1 - 8.7e-19 67.6 35.7 4.6e-18 65.3 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.6 CBZ33824.1 - 0.0091 16.1 0.3 0.022 14.8 0.3 1.7 1 0 0 1 1 1 1 PgaD-like protein Spo7 PF03907.13 CBZ33824.1 - 0.04 13.4 0.7 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Spo7-like protein DUF2427 PF10348.9 CBZ33824.1 - 0.087 12.6 0.5 0.087 12.6 0.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF3043 PF11241.8 CBZ33824.1 - 0.22 11.5 0.1 0.22 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Reticulon PF02453.17 CBZ33824.1 - 9.6 6.1 12.7 0.26 11.2 1.2 2.6 3 0 0 3 3 3 0 Reticulon Calpain_III PF01067.22 CBZ33827.1 - 8.5e-16 58.5 0.1 9e-06 26.0 0.0 4.9 3 2 0 3 3 3 3 Calpain large subunit, domain III LRR_6 PF13516.6 CBZ33827.1 - 0.039 14.0 0.6 11 6.4 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat JHY PF15261.6 CBZ33827.1 - 0.22 12.2 3.9 0.24 12.1 1.2 2.3 2 0 0 2 2 2 0 Jhy protein Calpain_III PF01067.22 CBZ33828.1 - 5.4e-11 42.9 0.0 4.1e-10 40.1 0.0 2.5 3 1 0 3 3 3 1 Calpain large subunit, domain III Topoisom_bac PF01131.20 CBZ33829.1 - 2.3e-75 254.2 0.0 4.5e-75 253.2 0.0 1.4 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CBZ33829.1 - 1.4e-14 54.2 0.0 3.7e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 CBZ33829.1 - 0.016 15.7 0.0 0.085 13.3 0.0 2.2 2 0 0 2 2 2 0 Toprim domain FleQ PF06490.11 CBZ33829.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ ACDC PF14733.6 CBZ33829.1 - 0.2 12.0 0.1 2.3 8.6 0.1 2.5 2 1 0 2 2 2 0 AP2-coincident C-terminal Pkinase PF00069.25 CBZ33830.1 - 4.2e-54 183.7 0.0 6.2e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33830.1 - 7e-32 110.7 0.0 1.1e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Guanylate_cyc PF00211.20 CBZ33830.1 - 0.0017 18.0 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Kdo PF06293.14 CBZ33830.1 - 0.002 17.5 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ33830.1 - 0.02 14.8 0.3 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ33830.1 - 0.031 13.1 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 CBZ33830.1 - 0.05 12.9 0.0 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Kinase-like DUF2523 PF10734.9 CBZ33830.1 - 0.15 12.7 2.7 0.43 11.2 2.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2523) RPN6_N PF18055.1 CBZ33831.1 - 0.2 12.0 1.8 0.98 9.8 0.0 2.9 4 0 0 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain Pkinase PF00069.25 CBZ33832.1 - 7.9e-37 127.0 0.0 1.2e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33832.1 - 7.5e-13 48.3 0.0 1.6e-11 44.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ33832.1 - 0.075 12.3 0.1 0.29 10.4 0.1 1.9 1 1 0 1 1 1 0 Kinase-like LRR_4 PF12799.7 CBZ33833.1 - 1.1e-10 41.6 1.3 0.026 14.9 0.0 6.4 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ33833.1 - 3.5e-05 23.5 14.6 0.46 10.7 0.1 8.8 9 0 0 9 9 9 2 Leucine Rich repeat LRR_8 PF13855.6 CBZ33833.1 - 0.00089 19.0 12.5 1.4 8.7 0.4 6.6 5 3 0 5 5 5 2 Leucine rich repeat PUF PF00806.19 CBZ33834.1 - 0.042 13.6 3.5 7.8 6.4 0.0 4.8 5 1 1 6 6 6 0 Pumilio-family RNA binding repeat CHAT PF12770.7 CBZ33835.1 - 2.3e-49 168.4 0.5 4.8e-49 167.3 0.5 1.6 1 0 0 1 1 1 1 CHAT domain LRR_6 PF13516.6 CBZ33835.1 - 0.037 14.1 12.0 0.66 10.2 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LCIB_C_CA PF18599.1 CBZ33835.1 - 0.18 11.1 0.3 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases LRR_1 PF00560.33 CBZ33835.1 - 0.68 10.7 4.2 27 5.9 1.7 3.2 2 1 0 2 2 2 0 Leucine Rich Repeat TPR_2 PF07719.17 CBZ33835.1 - 6.8 7.1 14.4 3.5 8.0 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ33835.1 - 7.5 6.9 23.8 0.1 12.9 0.6 5.5 4 2 3 7 7 7 0 Tetratricopeptide repeat LRR_4 PF12799.7 CBZ33835.1 - 9.2 6.8 6.2 37 4.9 0.2 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) MVP_shoulder PF11978.8 CBZ33837.1 - 1.2e-40 138.2 0.0 2.1e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault_3 PF17795.1 CBZ33837.1 - 3e-33 113.7 1.3 1.2e-29 102.1 0.1 3.6 4 0 0 4 4 4 2 Major Vault Protein Repeat domain Vault PF01505.18 CBZ33837.1 - 1e-29 102.4 0.1 3.5e-13 49.5 0.1 4.6 4 0 0 4 4 4 3 Major Vault Protein repeat domain Vault_4 PF17796.1 CBZ33837.1 - 8.3e-17 61.0 0.0 5.4e-15 55.2 0.0 3.3 3 0 0 3 3 3 1 Major Vault Protein repeat domain Vault_2 PF17794.1 CBZ33837.1 - 7.5e-12 45.4 3.9 1.3e-05 25.4 0.0 4.2 3 1 0 3 3 3 2 Major Vault Protein repeat domain NopRA1 PF16201.5 CBZ33838.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Nucleolar pre-ribosomal-associated protein 1 EF-hand_6 PF13405.6 CBZ33839.1 - 7.1e-11 41.1 1.5 0.00092 19.0 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBZ33839.1 - 5.1e-10 39.7 0.0 2.9e-05 24.4 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ33839.1 - 6e-09 34.8 0.1 0.013 15.0 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CBZ33839.1 - 2.1e-08 33.8 0.0 0.00014 21.7 0.1 3.3 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 CBZ33839.1 - 3.2e-06 27.4 0.4 0.0021 18.4 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CBZ33839.1 - 0.026 14.8 0.0 1.1 9.6 0.0 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dehydratase_SU PF02287.15 CBZ33839.1 - 0.046 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Dehydratase small subunit EF-hand_5 PF13202.6 CBZ33839.1 - 0.15 11.6 5.7 0.98 9.0 0.0 3.2 3 1 0 3 3 3 0 EF hand Actin PF00022.19 CBZ33840.1 - 2.8e-33 115.1 0.0 2.9e-32 111.8 0.0 2.0 1 1 0 1 1 1 1 Actin MAGI_u5 PF16666.5 CBZ33840.1 - 0.042 14.0 4.6 3.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Unstructured region on MAGI Hexokinase_1 PF00349.21 CBZ33841.1 - 9.6e-62 208.4 0.0 1.3e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 CBZ33841.1 - 1.7e-61 207.7 0.0 2.5e-61 207.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PPR_2 PF13041.6 CBZ33843.1 - 1.9e-14 53.5 0.4 2.6e-07 30.7 0.0 4.3 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 CBZ33843.1 - 4.1e-11 42.8 0.1 7.1e-07 29.2 0.0 4.3 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ33843.1 - 2.8e-06 26.9 0.3 0.0009 18.7 0.0 3.4 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CBZ33843.1 - 0.00021 21.3 4.4 4.1 7.9 0.1 6.5 7 0 0 7 7 7 1 PPR repeat PPR_1 PF12854.7 CBZ33843.1 - 0.0059 16.3 0.0 0.72 9.6 0.0 3.2 3 0 0 3 3 3 1 PPR repeat GMP_synt_C PF00958.22 CBZ33843.1 - 0.073 13.1 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 GMP synthase C terminal domain Pkinase PF00069.25 CBZ33844.1 - 2.5e-47 161.4 0.0 1.6e-46 158.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33844.1 - 5.8e-30 104.4 0.0 3.5e-22 78.9 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 CBZ33844.1 - 6.1e-05 22.7 0.1 0.00012 21.8 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 CBZ33844.1 - 0.07 12.4 0.0 6.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CBZ33844.1 - 0.24 11.3 0.0 0.24 11.3 0.0 4.1 3 2 1 4 4 4 0 Phosphotransferase enzyme family LRR_4 PF12799.7 CBZ33846.1 - 0.072 13.5 0.2 4.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ33846.1 - 0.12 11.9 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat DUF702 PF05142.12 CBZ33848.1 - 0.013 16.0 0.4 0.025 15.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF702) zf-U1 PF06220.12 CBZ33849.1 - 0.00011 21.9 4.1 0.00024 20.8 4.1 1.6 1 0 0 1 1 1 1 U1 zinc finger AKAP95 PF04988.12 CBZ33849.1 - 0.014 15.6 0.4 0.02 15.1 0.4 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.8 CBZ33849.1 - 0.017 15.4 0.3 0.048 14.0 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Vps51 PF08700.11 CBZ33850.1 - 2.5e-24 85.1 1.9 8e-24 83.5 1.9 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 CBZ33850.1 - 3.2e-07 30.4 0.2 6.4e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 CBZ33850.1 - 1.6e-06 27.0 2.2 2.8e-06 26.2 2.2 1.3 1 0 0 1 1 1 1 Dor1-like family Vps53_N PF04100.12 CBZ33850.1 - 4.6e-05 22.6 2.3 8.2e-05 21.7 2.3 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal COG2 PF06148.11 CBZ33850.1 - 8.2e-05 22.7 2.0 0.00028 21.0 2.0 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps54_N PF10475.9 CBZ33850.1 - 0.00084 18.7 3.3 0.0015 17.9 3.3 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 CBZ33850.1 - 0.0019 18.4 3.2 0.0074 16.5 3.2 2.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.9 CBZ33850.1 - 0.0083 16.2 2.3 0.0083 16.2 2.3 2.0 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 CBZ33850.1 - 0.048 14.0 0.7 0.21 11.9 0.7 2.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SEO_N PF14576.6 CBZ33850.1 - 0.052 12.7 0.7 0.11 11.6 0.7 1.5 1 0 0 1 1 1 0 Sieve element occlusion N-terminus Occludin_ELL PF07303.13 CBZ33850.1 - 0.056 14.2 0.2 0.2 12.4 0.2 1.9 1 0 0 1 1 1 0 Occludin homology domain DUF1664 PF07889.12 CBZ33850.1 - 0.15 12.1 0.8 0.68 10.0 0.8 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 CBZ33850.1 - 0.21 12.1 1.6 1.7 9.1 0.6 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ZapB PF06005.12 CBZ33850.1 - 0.65 10.5 2.8 3.2 8.3 0.6 3.1 1 1 1 2 2 2 0 Cell division protein ZapB Fib_alpha PF08702.10 CBZ33850.1 - 0.7 10.1 3.6 1.3 9.2 1.6 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.6 CBZ33850.1 - 5.5 7.5 6.2 5 7.6 3.0 2.8 2 0 0 2 2 1 0 Snapin/Pallidin Peptidase_M16 PF00675.20 CBZ33851.1 - 4.8e-10 39.6 0.0 9.9e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBZ33851.1 - 0.027 14.5 0.0 0.55 10.2 0.0 3.0 3 1 0 3 3 3 0 Peptidase M16 inactive domain DUF2922 PF11148.8 CBZ33851.1 - 0.17 11.7 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) MCU PF04678.13 CBZ33852.1 - 1e-18 68.0 6.0 1.2e-18 67.9 6.0 1.0 1 0 0 1 1 1 1 Mitochondrial calcium uniporter DUF2076 PF09849.9 CBZ33853.1 - 0.87 9.6 9.6 0.49 10.4 1.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) RPAP2_Rtr1 PF04181.13 CBZ33854.1 - 4.2e-07 30.2 0.6 3.8e-05 23.9 0.0 2.5 2 1 0 2 2 2 2 Rtr1/RPAP2 family Lant_dehydr_C PF14028.6 CBZ33854.1 - 0.038 13.5 0.4 0.038 13.5 0.4 1.9 2 0 0 2 2 2 0 Lantibiotic biosynthesis dehydratase C-term DUF667 PF05018.13 CBZ33855.1 - 7.5e-92 306.1 0.6 8.5e-92 306.0 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) UCH PF00443.29 CBZ33857.1 - 1.8e-45 155.4 0.6 2.3e-45 155.1 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ33857.1 - 9.7e-20 71.4 3.1 2.1e-19 70.3 3.1 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alpha-2-MRAP_N PF06400.11 CBZ33857.1 - 0.00021 21.2 3.7 0.00044 20.2 3.7 1.5 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, N-terminal domain CFIA_Pcf11 PF11526.8 CBZ33857.1 - 0.35 11.4 4.1 1.6 9.3 0.2 2.7 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Piwi PF02171.17 CBZ33858.1 - 4.5e-08 32.7 0.0 6.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain Pyr_redox_2 PF07992.14 CBZ33859.1 - 3.1e-11 43.0 0.5 2.6e-05 23.6 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ33859.1 - 4e-05 23.8 0.0 0.00029 21.0 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CBZ33859.1 - 0.00067 19.7 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CBZ33859.1 - 0.0035 17.9 0.2 0.31 11.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CBZ33859.1 - 0.025 14.6 0.4 15 5.6 0.0 3.3 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 CBZ33859.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Herpes_pp85 PF04637.12 CBZ33859.1 - 0.45 8.9 2.9 1.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) SPOC PF07744.13 CBZ33860.1 - 0.074 13.0 0.1 0.17 11.8 0.1 1.6 1 1 0 1 1 1 0 SPOC domain TFIIA PF03153.13 CBZ33860.1 - 0.15 12.1 13.7 0.19 11.7 13.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CBZ33860.1 - 0.32 10.6 9.7 0.47 10.0 9.7 1.4 1 0 0 1 1 1 0 Spt20 family Pro-rich PF15240.6 CBZ33860.1 - 0.89 9.8 35.3 1.3 9.3 35.3 1.1 1 0 0 1 1 1 0 Proline-rich TMEM189_B_dmain PF10520.9 CBZ33861.1 - 1.1e-66 224.2 2.3 1.5e-66 223.8 2.3 1.1 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain IBV_3A PF03617.13 CBZ33861.1 - 0.027 14.4 1.0 0.056 13.4 1.0 1.5 1 0 0 1 1 1 0 IBV 3A protein Vps35 PF03635.17 CBZ33864.1 - 8.6e-214 712.2 0.0 1e-213 712.0 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 EABR PF12180.8 CBZ33865.1 - 0.041 13.5 0.9 0.13 11.9 0.9 1.8 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 GPS2_interact PF15784.5 CBZ33865.1 - 0.044 14.2 0.5 0.11 13.0 0.3 1.9 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain RepA_C PF04796.12 CBZ33865.1 - 0.052 13.6 0.5 0.19 11.8 0.3 2.0 2 0 0 2 2 2 0 Plasmid encoded RepA protein Spc7 PF08317.11 CBZ33865.1 - 0.079 11.8 19.7 0.13 11.2 8.5 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein Fib_alpha PF08702.10 CBZ33865.1 - 0.096 12.9 4.1 0.29 11.3 0.8 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DUF4795 PF16043.5 CBZ33865.1 - 0.11 12.1 7.9 1.8 8.1 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) ATG16 PF08614.11 CBZ33865.1 - 0.16 12.2 36.4 0.58 10.4 14.6 3.5 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) 3-PAP PF12578.8 CBZ33865.1 - 0.18 11.6 2.2 6.1 6.6 0.1 3.3 3 0 0 3 3 3 0 Myotubularin-associated protein TPR_MLP1_2 PF07926.12 CBZ33865.1 - 0.26 11.4 28.3 0.29 11.2 0.5 3.2 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 CBZ33865.1 - 0.4 9.3 6.3 0.71 8.4 6.3 1.3 1 0 0 1 1 1 0 AAA domain DUF4686 PF15742.5 CBZ33865.1 - 0.43 9.7 17.3 0.85 8.7 17.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4686) TMF_TATA_bd PF12325.8 CBZ33865.1 - 0.53 10.5 18.2 0.45 10.8 3.7 3.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Occludin_ELL PF07303.13 CBZ33865.1 - 0.54 11.0 10.5 11 6.8 0.2 3.9 2 1 0 3 3 3 0 Occludin homology domain DUF1664 PF07889.12 CBZ33865.1 - 1.2 9.2 4.6 2.1 8.4 1.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 CBZ33865.1 - 1.5 9.1 5.3 1.5 9.1 3.7 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein BRE1 PF08647.11 CBZ33865.1 - 1.7 8.8 11.4 10 6.3 0.0 3.4 2 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase Fez1 PF06818.15 CBZ33865.1 - 1.7 9.0 19.5 15 6.0 17.7 2.5 1 1 1 2 2 2 0 Fez1 DUF812 PF05667.11 CBZ33865.1 - 1.9 7.3 14.2 3.1 6.6 14.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) YabA PF06156.13 CBZ33865.1 - 2 9.1 7.9 2.4 8.8 0.2 3.8 4 1 1 5 5 3 0 Initiation control protein YabA FlxA PF14282.6 CBZ33865.1 - 2.1 8.4 13.3 4.6 7.3 5.7 2.9 2 1 1 3 3 2 0 FlxA-like protein DUF724 PF05266.14 CBZ33865.1 - 4.6 7.0 12.6 1.8 8.4 1.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) GAS PF13851.6 CBZ33865.1 - 5.5 6.3 16.0 0.44 9.9 3.1 3.2 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 CBZ33865.1 - 7.1 5.9 25.0 0.63 9.4 0.2 3.8 2 1 2 4 4 3 0 Tropomyosin DnaJ_C PF01556.18 CBZ33866.1 - 4.2e-32 111.3 0.0 5.9e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ33866.1 - 5.9e-27 93.6 1.5 1e-26 92.8 1.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ33866.1 - 3.6e-14 52.9 11.8 7.4e-14 51.9 11.8 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ33866.1 - 0.003 17.5 11.7 0.077 13.0 2.2 2.7 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 CBZ33866.1 - 0.057 13.5 5.3 1.2 9.2 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF2614 PF11023.8 CBZ33866.1 - 0.25 11.5 0.2 0.66 10.1 0.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF2318 PF10080.9 CBZ33866.1 - 0.84 9.8 4.5 2 8.6 0.5 2.5 1 1 0 2 2 2 0 Predicted membrane protein (DUF2318) zinc_ribbon_5 PF13719.6 CBZ33866.1 - 0.98 9.2 5.3 5.5 6.8 1.8 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CBZ33866.1 - 1.1 9.3 3.8 2.4 8.2 3.8 1.5 1 0 0 1 1 1 0 zinc-ribbons HypA PF01155.19 CBZ33866.1 - 3.8 7.6 7.4 2.6 8.1 1.1 2.4 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Bacteriocin_IIc PF10439.9 CBZ33868.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.7 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide TPR_14 PF13428.6 CBZ33870.1 - 2.6e-16 58.9 27.9 0.021 15.6 0.2 9.9 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ33870.1 - 3.1e-14 53.2 18.2 0.00016 22.2 0.0 7.2 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ33870.1 - 5.4e-12 44.8 21.1 0.012 15.6 0.5 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ33870.1 - 3.9e-10 39.1 8.8 0.013 15.3 0.5 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ33870.1 - 1.1e-08 35.6 36.4 0.00026 21.6 0.0 8.3 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ33870.1 - 1.1e-07 32.0 23.5 0.086 13.1 0.3 6.6 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ33870.1 - 1.9e-06 27.5 9.5 7.7 6.8 0.1 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ33870.1 - 6.8e-06 26.2 21.5 0.21 11.8 0.0 5.9 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CBZ33870.1 - 1.4e-05 24.9 4.0 1.1 9.6 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBZ33870.1 - 0.00018 21.1 2.6 0.092 12.4 0.0 4.8 5 0 0 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_9 PF13371.6 CBZ33870.1 - 0.00039 20.5 12.9 0.0017 18.4 0.3 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ33870.1 - 0.019 14.6 7.5 9 6.1 0.0 5.1 5 0 0 5 5 5 0 TPR repeat TPR_6 PF13174.6 CBZ33870.1 - 0.097 13.4 17.0 12 6.8 0.1 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ33870.1 - 1.1 9.2 17.7 0.37 10.7 0.1 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_20 PF14561.6 CBZ33870.1 - 1.4 9.3 4.5 11 6.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat La PF05383.17 CBZ33871.1 - 1.2e-21 76.5 0.0 2.3e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CBZ33871.1 - 3.7e-06 26.7 0.2 0.00069 19.4 0.1 3.2 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBZ33871.1 - 9.5e-05 22.4 1.8 0.002 18.2 0.6 2.7 2 1 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 CBZ33871.1 - 9.9e-05 22.4 0.2 0.0043 17.1 0.1 2.2 2 0 0 2 2 2 1 RNA recognition motif PTS_2-RNA PF01885.16 CBZ33871.1 - 0.013 15.5 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family DUF5396 PF17374.2 CBZ33871.1 - 0.021 12.7 0.0 0.031 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5396) AbiEi_2 PF09952.9 CBZ33871.1 - 0.13 12.5 0.0 0.98 9.7 0.0 2.2 1 1 1 2 2 2 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Pallilysin PF18663.1 CBZ33871.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Pallilysin beta barrel domain Biotin_lipoyl PF00364.22 CBZ33872.1 - 1.1e-27 95.6 1.7 1.2e-12 47.4 0.1 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme HlyD_3 PF13437.6 CBZ33872.1 - 0.003 18.2 0.2 4.6 8.0 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein E3_binding PF02817.17 CBZ33872.1 - 0.015 15.6 0.4 0.056 13.8 0.3 2.1 1 1 0 1 1 1 0 e3 binding domain PYNP_C PF07831.13 CBZ33872.1 - 0.015 14.9 0.2 8.8 6.1 0.0 2.7 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF2779 PF11074.8 CBZ33872.1 - 0.051 14.0 0.0 15 6.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) DUF3606 PF12244.8 CBZ33872.1 - 0.11 12.5 0.2 0.58 10.1 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) DUF2118 PF09891.9 CBZ33872.1 - 0.15 12.0 0.3 23 4.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) TALPID3 PF15324.6 CBZ33872.1 - 6 4.4 10.9 1.1 6.9 1.3 2.1 2 0 0 2 2 2 0 Hedgehog signalling target CadC_C1 PF18500.1 CBZ33873.1 - 0.022 14.9 0.1 0.029 14.5 0.1 1.2 1 0 0 1 1 1 0 CadC C-terminal domain 1 SNARE PF05739.19 CBZ33873.1 - 0.47 10.5 3.9 0.86 9.6 2.7 2.0 2 1 0 2 2 2 0 SNARE domain CTD_bind PF04818.13 CBZ33875.1 - 0.06 14.2 0.0 0.26 12.1 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase II-binding domain. BssS PF13991.6 CBZ33875.1 - 0.11 12.6 0.0 0.45 10.6 0.0 2.1 2 0 0 2 2 2 0 BssS protein family DUF4916 PF16262.5 CBZ33877.1 - 0.051 13.1 0.8 0.085 12.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4916) DEAD PF00270.29 CBZ33878.1 - 1.8e-15 57.2 0.0 2.4e-11 43.7 0.0 3.1 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ33878.1 - 6.1e-15 55.5 0.0 2.7e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ33878.1 - 0.00048 20.2 0.0 0.003 17.6 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CBZ33878.1 - 0.099 11.9 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain IMS PF00817.20 CBZ33879.1 - 2.8e-25 89.1 0.1 3.4e-25 88.8 0.1 1.1 1 0 0 1 1 1 1 impB/mucB/samB family IMS PF00817.20 CBZ33880.1 - 5.4e-33 114.1 0.1 6.2e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 impB/mucB/samB family PGM_PMM_I PF02878.16 CBZ33881.1 - 1.9e-30 105.4 0.1 3.2e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CBZ33881.1 - 2.2e-25 89.1 0.0 5.1e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CBZ33881.1 - 7e-10 39.0 0.0 1.8e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 CBZ33881.1 - 9e-10 39.1 0.2 4.6e-09 36.8 0.2 2.2 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II ParA PF10609.9 CBZ33883.1 - 1.5e-88 296.4 0.0 1.8e-88 296.2 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CBZ33883.1 - 5.5e-12 45.8 0.0 5.2e-11 42.7 0.0 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CBZ33883.1 - 2.7e-07 30.7 0.4 4.4e-06 26.7 0.4 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CBZ33883.1 - 8.3e-07 28.5 0.0 1.4e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CBZ33883.1 - 0.00025 20.3 0.5 0.00051 19.3 0.1 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 CBZ33883.1 - 0.0036 16.3 0.4 0.0058 15.7 0.4 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CBZ33883.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_26 PF13500.6 CBZ33883.1 - 0.025 14.4 0.4 0.16 11.8 0.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBZ33883.1 - 0.03 14.1 0.9 0.069 12.9 0.2 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CBZ33883.1 - 0.035 13.3 0.2 0.06 12.5 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 CBZ33883.1 - 0.036 14.6 0.0 0.058 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ33883.1 - 0.039 14.3 0.2 0.072 13.5 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 CBZ33883.1 - 0.042 13.4 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 CBZ33883.1 - 0.044 13.2 0.2 0.095 12.1 0.2 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Rad17 PF03215.15 CBZ33883.1 - 0.091 12.7 0.1 0.27 11.1 0.1 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 CBZ33883.1 - 0.2 11.3 0.5 0.65 9.6 0.3 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.12 CBZ33883.1 - 0.2 11.6 0.5 0.35 10.8 0.5 1.4 1 0 0 1 1 1 0 NACHT domain CBP_BcsQ PF06564.12 CBZ33883.1 - 0.21 11.0 0.1 0.66 9.4 0.1 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ RNA_helicase PF00910.22 CBZ33883.1 - 0.21 12.0 0.1 0.39 11.1 0.1 1.4 1 0 0 1 1 1 0 RNA helicase MSC PF09402.10 CBZ33883.1 - 1.1 8.6 4.9 1.7 8.1 4.9 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Lactamase_B PF00753.27 CBZ33884.1 - 3.8e-17 62.9 1.1 7.9e-17 61.9 0.3 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 CBZ33884.1 - 9.2e-11 41.6 0.1 2e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 CBZ33884.1 - 0.00023 20.7 0.4 0.00054 19.5 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CBZ33884.1 - 0.0044 16.9 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain STAR_dimer PF16544.5 CBZ33884.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein Hist_deacetyl PF00850.19 CBZ33885.1 - 1.4e-67 228.4 0.1 1.8e-67 228.0 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DSPc PF00782.20 CBZ33887.1 - 1.3e-18 67.1 0.0 1.9e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain ABC_tran PF00005.27 CBZ33888.1 - 1.4e-36 126.0 0.0 1.1e-17 64.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ33888.1 - 6e-11 42.7 2.2 0.0059 16.5 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ33888.1 - 1.4e-10 41.0 2.9 0.00066 19.2 0.2 3.9 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain RLI PF04068.15 CBZ33888.1 - 5e-09 35.8 5.5 1.4e-08 34.4 5.5 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Fer4 PF00037.27 CBZ33888.1 - 1.1e-07 31.3 2.2 1.1e-07 31.3 2.2 2.2 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_16 PF13191.6 CBZ33888.1 - 1.8e-06 28.5 0.0 0.0062 16.9 0.0 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CBZ33888.1 - 3.1e-06 27.1 0.0 0.025 14.3 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 CBZ33888.1 - 9.8e-06 26.2 0.5 0.009 16.5 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBZ33888.1 - 4.2e-05 23.2 0.4 0.16 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4_21 PF14697.6 CBZ33888.1 - 0.00011 22.3 14.7 0.00025 21.1 14.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CBZ33888.1 - 0.00011 22.1 2.3 0.00011 22.1 2.3 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain RsgA_GTPase PF03193.16 CBZ33888.1 - 0.00033 20.6 0.1 0.15 11.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CBZ33888.1 - 0.0005 20.3 0.1 0.094 13.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 CBZ33888.1 - 0.00051 20.5 0.0 0.034 14.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CBZ33888.1 - 0.00052 20.3 0.0 1.1 9.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CBZ33888.1 - 0.00081 19.3 0.3 0.021 14.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 CBZ33888.1 - 0.001 19.4 0.0 0.52 10.7 0.0 3.2 3 0 0 3 3 3 1 RNA helicase Rad17 PF03215.15 CBZ33888.1 - 0.001 19.0 0.0 0.89 9.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 CBZ33888.1 - 0.0011 18.7 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Fer4_7 PF12838.7 CBZ33888.1 - 0.0013 19.3 0.2 0.0013 19.3 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_5 PF07728.14 CBZ33888.1 - 0.0019 18.2 0.3 0.55 10.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Fer4_10 PF13237.6 CBZ33888.1 - 0.0027 17.8 1.3 0.0027 17.8 1.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain TsaE PF02367.17 CBZ33888.1 - 0.0038 17.2 0.0 0.018 15.1 0.0 1.9 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 CBZ33888.1 - 0.0039 16.9 0.3 0.66 9.6 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 CBZ33888.1 - 0.0082 15.7 0.1 0.35 10.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CBZ33888.1 - 0.0083 16.3 0.0 3.6 7.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 CBZ33888.1 - 0.01 15.5 0.1 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBZ33888.1 - 0.01 15.6 0.1 0.97 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBZ33888.1 - 0.015 15.9 0.0 7.6 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CBZ33888.1 - 0.017 15.2 0.0 4.3 7.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fer4_3 PF12798.7 CBZ33888.1 - 0.031 15.2 4.0 0.031 15.2 4.0 2.7 2 0 0 2 2 1 0 4Fe-4S binding domain AAA_14 PF13173.6 CBZ33888.1 - 0.032 14.3 0.0 0.97 9.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ33888.1 - 0.04 14.2 0.1 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CBZ33888.1 - 0.045 13.0 0.0 4.9 6.4 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 CBZ33888.1 - 0.052 13.1 0.0 0.77 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 CBZ33888.1 - 0.12 12.6 14.5 0.38 11.0 14.6 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 CBZ33888.1 - 0.14 11.8 0.4 15 5.2 0.0 3.2 3 0 0 3 3 3 0 Thymidylate kinase NB-ARC PF00931.22 CBZ33888.1 - 0.15 11.2 0.4 7.1 5.7 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain PduV-EutP PF10662.9 CBZ33888.1 - 0.43 10.3 1.5 1.2 8.9 0.0 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MukB PF04310.12 CBZ33888.1 - 0.71 9.6 3.1 23 4.7 0.1 3.4 4 0 0 4 4 4 0 MukB N-terminal Leu_Phe_trans PF03588.14 CBZ33890.1 - 0.014 14.9 0.0 0.13 11.7 0.0 2.3 3 0 0 3 3 3 0 Leucyl/phenylalanyl-tRNA protein transferase Ribosomal_L36e PF01158.18 CBZ33891.1 - 1.2e-28 99.1 1.8 1.4e-28 99.0 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Corona_M PF01635.18 CBZ33891.1 - 0.28 10.5 0.0 0.35 10.1 0.0 1.1 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein DUF543 PF04418.12 CBZ33892.1 - 6.3e-14 51.7 0.2 8.5e-14 51.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ParA PF10609.9 CBZ33892.1 - 0.02 14.4 0.0 0.029 13.8 0.0 1.3 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DLH PF01738.18 CBZ33892.1 - 0.051 13.1 0.1 0.053 13.1 0.1 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family ATP-synt_C PF00137.21 CBZ33893.1 - 1.8e-06 28.2 14.5 1.8e-06 28.2 14.5 1.6 2 0 0 2 2 2 1 ATP synthase subunit C PCI PF01399.27 CBZ33895.1 - 8e-13 48.8 1.9 1.6e-12 47.9 0.2 2.4 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CBZ33895.1 - 4.3e-05 23.5 0.7 0.0003 20.8 0.3 2.5 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain Vps39_1 PF10366.9 CBZ33895.1 - 0.66 10.3 8.8 8.9 6.6 1.6 3.6 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 Sec34 PF04136.15 CBZ33895.1 - 2.9 7.8 12.1 0.66 9.9 1.5 4.0 3 2 1 4 4 4 0 Sec34-like family Ras PF00071.22 CBZ33898.1 - 8.5e-46 155.5 0.0 1e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ33898.1 - 6e-34 116.8 0.0 8.3e-34 116.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ33898.1 - 2e-10 40.4 0.0 3.8e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBZ33898.1 - 4.1e-06 26.5 0.0 1.2e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ33898.1 - 0.0001 22.2 0.0 0.031 14.2 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CBZ33898.1 - 0.00045 19.6 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ33898.1 - 0.00091 19.3 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBZ33898.1 - 0.037 13.5 0.0 0.08 12.4 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CBZ33898.1 - 0.12 12.7 0.1 0.2 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBZ33898.1 - 0.18 12.1 0.0 0.47 10.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain Not1 PF04054.15 CBZ33900.1 - 6.1e-94 315.0 6.8 6.1e-94 315.0 6.8 1.9 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CBZ33900.1 - 1e-75 254.0 0.1 2.3e-75 252.9 0.1 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 CBZ33900.1 - 2.2e-47 160.7 0.0 1.1e-46 158.4 0.0 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CBZ33900.1 - 3.5e-24 85.4 1.5 9.6e-24 84.0 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) tRNA-synt_1g PF09334.11 CBZ33901.1 - 1.6e-97 326.7 0.5 5.3e-97 325.0 0.5 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CBZ33901.1 - 1.4e-18 66.5 1.7 2.4e-08 32.7 1.5 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CBZ33901.1 - 3.8e-08 33.0 0.1 0.0023 17.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain MKT1_C PF12246.8 CBZ33902.1 - 6.4e-14 51.8 0.0 1.1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CBZ33902.1 - 1.4e-11 44.6 0.0 2.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication CCDC53 PF10152.9 CBZ33902.1 - 1.8 8.9 3.6 58 4.1 0.0 2.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Filament PF00038.21 CBZ33904.1 - 0.0019 17.8 12.5 0.0019 17.8 12.5 14.8 6 3 5 13 13 13 6 Intermediate filament protein DUF4833 PF16117.5 CBZ33906.1 - 9.3e-18 64.6 0.3 1.4e-08 34.9 0.1 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4833) NinG PF05766.12 CBZ33906.1 - 0.098 12.6 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF4833 PF16117.5 CBZ33907.1 - 1.7e-21 76.7 1.2 5.4e-11 42.7 0.1 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4833) Peptidase_M24 PF00557.24 CBZ33908.1 - 1.2e-41 142.7 0.1 1.8e-41 142.1 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 BAF1_ABF1 PF04684.13 CBZ33908.1 - 0.3 10.1 3.0 0.54 9.3 3.0 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor FliE PF02049.18 CBZ33908.1 - 0.58 10.3 4.2 17 5.6 2.1 3.1 3 0 0 3 3 3 0 Flagellar hook-basal body complex protein FliE MWFE PF15879.5 CBZ33909.1 - 0.073 13.2 2.0 7.5 6.8 0.0 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit DUF2730 PF10805.8 CBZ33909.1 - 0.097 12.8 1.9 0.23 11.6 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Pribosyltran PF00156.27 CBZ33910.1 - 1.3e-20 73.5 0.1 1.7e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran PF00156.27 CBZ33911.1 - 2e-18 66.4 0.0 2.8e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pkinase PF00069.25 CBZ33912.1 - 1.1e-52 179.0 0.0 5.1e-37 127.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33912.1 - 3.2e-27 95.5 0.0 9e-18 64.5 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ33912.1 - 2.8e-09 36.7 0.0 5.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like BAG PF02179.16 CBZ33913.1 - 0.00047 20.5 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 BAG domain zinc_ribbon_12 PF11331.8 CBZ33915.1 - 0.072 12.9 0.0 0.072 12.9 0.0 4.5 5 1 1 6 6 6 0 Probable zinc-ribbon domain HEAT PF02985.22 CBZ33917.1 - 0.028 14.7 1.0 1.2 9.6 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat Pkinase PF00069.25 CBZ33917.1 - 0.076 12.4 0.0 0.15 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein kinase domain HEAT_2 PF13646.6 CBZ33917.1 - 0.26 11.7 3.1 1.2 9.5 1.5 3.0 2 1 1 3 3 3 0 HEAT repeats HEAT_2 PF13646.6 CBZ33918.1 - 1.1e-10 41.8 1.9 0.00035 20.9 0.0 4.7 5 1 0 5 5 5 2 HEAT repeats DUF4042 PF13251.6 CBZ33918.1 - 1.7e-07 31.1 1.0 0.00016 21.5 0.2 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 CBZ33918.1 - 6.3e-07 29.8 11.3 0.013 16.0 0.1 6.7 5 1 1 6 6 6 2 HEAT-like repeat HEAT PF02985.22 CBZ33918.1 - 1.3e-06 28.1 3.9 1.1 9.7 0.0 6.6 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 CBZ33918.1 - 0.0036 17.4 0.0 0.0079 16.2 0.0 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBZ33918.1 - 0.11 11.0 0.0 0.26 9.8 0.0 1.5 1 1 0 1 1 1 0 Adaptin N terminal region HEAT_PBS PF03130.16 CBZ33918.1 - 0.54 11.1 2.7 37 5.4 0.0 4.7 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat ABC2_membrane PF01061.24 CBZ33919.1 - 1.7e-07 30.9 15.5 3.2e-07 30.0 15.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBZ33919.1 - 2.6e-06 28.0 0.0 4.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 CBZ33919.1 - 0.0054 16.6 0.0 0.021 14.7 0.0 2.0 1 0 0 1 1 1 1 CDR ABC transporter Rab5ip PF07019.12 CBZ33919.1 - 7.5 7.2 10.9 2.3 8.9 4.6 3.0 2 1 1 3 3 3 0 Rab5-interacting protein (Rab5ip) ATP1G1_PLM_MAT8 PF02038.16 CBZ33920.1 - 0.088 12.3 0.2 0.14 11.6 0.2 1.2 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family MIG-14_Wnt-bd PF06664.12 CBZ33920.1 - 0.12 11.5 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF4499 PF14934.6 CBZ33921.1 - 2.9e-07 30.7 2.9 4.8e-07 30.0 2.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) MutS_V PF00488.21 CBZ33922.1 - 3.1e-31 108.9 0.0 8.4e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CBZ33922.1 - 2.1e-17 64.0 0.2 2.9e-16 60.3 0.0 2.6 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CBZ33922.1 - 0.0011 19.3 0.1 0.0022 18.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain II AAA_21 PF13304.6 CBZ33922.1 - 0.0021 18.0 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CBZ33922.1 - 0.0077 16.6 0.0 0.0077 16.6 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.6 CBZ33922.1 - 0.014 15.6 0.1 0.12 12.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CBZ33922.1 - 0.055 13.5 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBZ33922.1 - 0.12 12.9 0.1 0.27 11.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 CBZ33922.1 - 0.21 12.0 0.0 0.49 10.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 CBZ33922.1 - 0.22 11.4 0.1 0.39 10.6 0.1 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CBZ33922.1 - 0.25 11.8 0.1 0.47 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain CAP_C PF08603.11 CBZ33923.1 - 1e-18 67.5 0.1 1.5e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 CBZ33923.1 - 3.6e-10 39.8 8.3 1.8e-07 30.9 0.0 3.9 3 1 1 4 4 4 2 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 CBZ33923.1 - 0.017 14.8 0.3 0.035 13.8 0.3 1.4 1 0 0 1 1 1 0 Tubulin binding cofactor C tRNA-synt_2 PF00152.20 CBZ33924.1 - 7.5e-64 215.8 0.0 2.5e-63 214.0 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBZ33924.1 - 1e-08 35.0 0.0 1.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBZ33924.1 - 2.9e-06 26.9 0.2 0.0089 15.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Transposase_23 PF03017.14 CBZ33924.1 - 0.086 12.8 0.0 0.47 10.4 0.0 2.1 2 0 0 2 2 2 0 TNP1/EN/SPM transposase DUF3813 PF12758.7 CBZ33925.1 - 0.085 13.2 0.5 0.23 11.8 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) tRNA_edit PF04073.15 CBZ33927.1 - 1e-07 32.0 0.0 2.3e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Sugarporin_N PF11471.8 CBZ33927.1 - 0.0082 16.1 0.2 0.024 14.6 0.0 1.9 2 0 0 2 2 2 1 Maltoporin periplasmic N-terminal extension Histone_H2A_C PF16211.5 CBZ33928.1 - 4.6e-10 39.1 0.9 1e-09 37.9 0.9 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBZ33928.1 - 6.5e-06 26.5 0.0 9.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CBZ33929.1 - 4.6e-10 39.1 0.9 1e-09 37.9 0.9 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CBZ33929.1 - 6.6e-06 26.5 0.0 9.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PDCD2_C PF04194.13 CBZ33931.1 - 3.8e-27 95.5 0.3 3.8e-27 95.5 0.3 2.3 2 2 1 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain SET PF00856.28 CBZ33933.1 - 0.083 13.3 0.0 0.38 11.1 0.0 2.2 1 1 0 1 1 1 0 SET domain YolD PF08863.10 CBZ33933.1 - 0.16 12.0 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 YolD-like protein Clathrin PF00637.20 CBZ33934.1 - 1.4e-12 47.7 17.8 0.011 15.6 0.0 9.6 5 3 4 11 11 11 2 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 CBZ33934.1 - 5.1e-07 29.9 0.0 0.076 13.3 0.0 4.6 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_4 PF07721.14 CBZ33934.1 - 7.9e-06 26.0 10.1 0.35 11.6 0.0 8.6 7 1 1 8 8 8 1 Tetratricopeptide repeat WD40 PF00400.32 CBZ33934.1 - 3.7e-05 24.4 2.2 1.1 10.2 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat PPR PF01535.20 CBZ33934.1 - 0.00013 22.0 6.1 7.5 7.0 0.5 7.4 5 1 1 6 6 6 1 PPR repeat Coatomer_WDAD PF04053.14 CBZ33934.1 - 0.0013 17.8 12.2 0.004 16.3 1.1 5.2 4 2 2 6 6 6 1 Coatomer WD associated region PTAC PF06130.12 CBZ33934.1 - 0.039 14.1 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Phosphate propanoyltransferase ANAPC3 PF12895.7 CBZ33934.1 - 0.057 13.6 0.0 0.057 13.6 0.0 6.8 7 2 0 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF294_C PF10335.9 CBZ33934.1 - 0.061 13.1 0.3 0.17 11.7 0.3 1.8 1 0 0 1 1 1 0 Putative nucleotidyltransferase substrate binding domain PP_kinase_C_1 PF17941.1 CBZ33934.1 - 0.066 12.8 0.2 0.27 10.8 0.1 2.0 2 0 0 2 2 2 0 Polyphosphate kinase C-terminal domain 1 TPR_2 PF07719.17 CBZ33934.1 - 0.3 11.3 41.6 0.24 11.6 0.1 11.1 12 0 0 12 12 10 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ33934.1 - 0.49 10.1 8.5 10 5.9 0.1 4.9 5 0 0 5 5 5 0 TPR repeat PPR_2 PF13041.6 CBZ33934.1 - 0.51 10.6 4.6 14 6.0 0.5 5.1 5 0 0 5 5 5 0 PPR repeat family TPR_8 PF13181.6 CBZ33934.1 - 1.9 8.9 23.6 24 5.4 0.0 8.3 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ33934.1 - 3 8.1 30.2 2.1 8.6 0.0 10.9 14 1 1 15 15 14 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ33934.1 - 3.7 8.6 47.3 12 7.1 0.1 15.2 12 7 5 17 17 15 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ33934.1 - 5.8 6.9 36.8 6.3 6.8 0.1 10.9 11 1 1 12 12 12 0 Tetratricopeptide repeat DUF4795 PF16043.5 CBZ33936.1 - 0.014 15.0 0.0 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Lzipper-MIP1 PF14389.6 CBZ33936.1 - 0.96 9.8 11.2 0.087 13.1 0.2 4.3 4 0 0 4 4 4 0 Leucine-zipper of ternary complex factor MIP1 DUF4596 PF15363.6 CBZ33936.1 - 5 7.4 8.7 9.9 6.5 4.3 4.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Tubulin PF00091.25 CBZ33937.1 - 2.4e-62 210.6 0.0 3.3e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ33937.1 - 6.9e-23 81.2 0.0 1.1e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CBZ33937.1 - 0.00012 21.4 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin like Bombesin PF02044.17 CBZ33937.1 - 0.16 12.1 1.2 0.36 11.0 1.2 1.6 1 0 0 1 1 1 0 Bombesin-like peptide Ax_dynein_light PF10211.9 CBZ33938.1 - 6.5e-49 166.4 1.7 9.9e-49 165.8 1.7 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain CCDC66 PF15236.6 CBZ33939.1 - 0.77 9.6 52.4 0.078 12.8 46.5 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 66 Kinesin PF00225.23 CBZ33940.1 - 6.7e-85 284.9 0.4 1.2e-84 284.1 0.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ33940.1 - 4.4e-13 49.4 0.0 2e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding DUF3958 PF13125.6 CBZ33940.1 - 0.0037 17.5 11.0 0.0037 17.5 11.0 4.7 5 0 0 5 5 5 1 Protein of unknown function (DUF3958) Exonuc_VII_L PF02601.15 CBZ33940.1 - 4 6.9 24.0 0.23 11.0 4.6 4.3 4 0 0 4 4 4 0 Exonuclease VII, large subunit DUF948 PF06103.11 CBZ33940.1 - 9.2 6.6 5.9 8.4 6.7 1.3 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Ribosomal_L6 PF00347.23 CBZ33941.1 - 1.8e-27 95.8 4.2 6.9e-15 55.5 0.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glyco_hydro_65C PF03633.15 CBZ33941.1 - 0.061 13.2 0.1 48 4.0 0.0 3.3 3 0 0 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain Ribosom_S12_S23 PF00164.25 CBZ33942.1 - 2.6e-48 162.4 0.4 2.6e-48 162.4 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.25 CBZ33943.1 - 2.6e-48 162.4 0.4 2.6e-48 162.4 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein S12/S23 Pkinase PF00069.25 CBZ33944.1 - 4.6e-73 245.8 0.0 5.5e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33944.1 - 7.4e-34 117.2 0.0 9.3e-34 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ33944.1 - 0.0011 19.0 0.9 0.022 14.7 0.3 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ33944.1 - 0.0016 17.8 0.0 0.033 13.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CBZ33944.1 - 0.0065 15.8 0.6 0.012 14.9 0.6 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ33944.1 - 0.083 11.8 0.0 10 4.9 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Cpn60_TCP1 PF00118.24 CBZ33945.1 - 1.3e-143 479.2 9.0 1.6e-143 478.9 9.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Colicin PF01024.19 CBZ33945.1 - 0.012 15.5 0.2 0.032 14.1 0.2 1.7 1 0 0 1 1 1 0 Colicin pore forming domain Tau95 PF09734.9 CBZ33946.1 - 5.8e-20 72.5 0.0 1.1e-19 71.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CBZ33946.1 - 0.00059 20.0 0.0 0.058 13.6 0.0 2.7 2 0 0 2 2 2 2 Tau95 Triple barrel domain IQ PF00612.27 CBZ33947.1 - 5.1e-11 41.4 201.1 4.4e-05 22.9 0.1 24.3 25 1 2 27 27 27 12 IQ calmodulin-binding motif TPR_1 PF00515.28 CBZ33947.1 - 1.1e-05 25.0 0.0 0.98 9.4 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ33947.1 - 0.0016 18.2 0.8 0.043 13.7 0.2 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ33947.1 - 0.023 14.9 0.0 8.7 6.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1749 PF08538.10 CBZ33947.1 - 0.14 11.2 0.1 0.29 10.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) TPR_2 PF07719.17 CBZ33947.1 - 0.34 11.1 5.7 4.2 7.7 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 CBZ33948.1 - 5.1e-14 52.4 12.5 0.0063 17.3 0.4 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ33948.1 - 1.1e-05 25.6 0.0 6.8 7.1 0.0 4.4 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ33948.1 - 0.012 14.3 0.0 0.024 13.3 0.0 1.5 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ribosomal_L13 PF00572.18 CBZ33948.1 - 0.023 14.9 0.1 6.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L13 Nbas_N PF15492.6 CBZ33948.1 - 0.032 13.6 0.0 1.4 8.2 0.0 2.4 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Golgin_A5 PF09787.9 CBZ33949.1 - 0.00019 21.0 0.0 0.00019 21.0 0.0 4.4 4 1 1 5 5 5 2 Golgin subfamily A member 5 SHE3 PF17078.5 CBZ33949.1 - 0.55 9.9 15.6 0.29 10.8 5.6 2.7 3 0 0 3 3 3 0 SWI5-dependent HO expression protein 3 DUF948 PF06103.11 CBZ33949.1 - 0.81 10.0 5.0 6.7 7.0 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Tho2 PF11262.8 CBZ33949.1 - 6.6 5.8 13.1 0.25 10.5 2.0 2.8 1 1 2 3 3 3 0 Transcription factor/nuclear export subunit protein 2 LRR_8 PF13855.6 CBZ33953.1 - 5.3e-23 80.6 15.3 1.7e-05 24.5 2.7 5.4 2 2 4 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 CBZ33953.1 - 5.4e-16 58.4 16.2 1.7e-05 25.1 2.2 6.7 3 2 5 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ33953.1 - 3.9e-07 29.7 10.2 0.14 12.8 0.1 8.8 10 1 0 10 10 10 2 Leucine Rich Repeat LRRNT_2 PF08263.12 CBZ33953.1 - 0.03 14.6 0.2 0.03 14.6 0.2 3.6 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 CBZ33953.1 - 0.066 13.3 14.2 5.2 7.4 0.3 7.3 8 0 0 8 8 8 0 Leucine Rich repeat MazE_antitoxin PF04014.18 CBZ33953.1 - 0.11 12.5 0.1 62 3.7 0.0 4.4 5 0 0 5 5 5 0 Antidote-toxin recognition MazE, bacterial antitoxin Ribosomal_L1 PF00687.21 CBZ33954.1 - 8.4e-09 35.4 0.0 1.3e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family PIF1 PF05970.14 CBZ33955.1 - 1.5e-33 116.5 0.0 3.5e-23 82.4 0.0 3.7 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.6 CBZ33955.1 - 4.8e-13 49.3 1.7 1.8e-09 37.6 0.8 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CBZ33955.1 - 1.1e-10 42.1 0.1 5.7e-10 39.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CBZ33955.1 - 7.1e-06 25.9 0.1 0.17 11.6 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 CBZ33955.1 - 0.00013 21.7 0.1 0.0086 15.9 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 CBZ33955.1 - 0.0022 17.8 0.1 0.0048 16.7 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.21 CBZ33955.1 - 0.0026 17.2 0.3 0.0053 16.2 0.3 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBZ33955.1 - 0.0055 16.7 0.2 0.17 11.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_32 PF13654.6 CBZ33955.1 - 0.0057 15.5 0.0 0.0084 14.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CBZ33955.1 - 0.0062 16.1 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 CBZ33955.1 - 0.01 16.2 0.4 0.036 14.4 0.4 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_11 PF13086.6 CBZ33955.1 - 0.015 15.1 0.3 0.23 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Herpes_Helicase PF02689.14 CBZ33955.1 - 0.02 12.9 0.1 0.085 10.8 0.0 1.9 3 0 0 3 3 3 0 Helicase AAA_7 PF12775.7 CBZ33955.1 - 0.024 14.1 0.0 0.88 9.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 CBZ33955.1 - 0.035 13.3 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CBZ33955.1 - 0.043 13.7 0.1 0.14 12.0 0.1 1.9 1 1 0 1 1 1 0 NTPase AAA_24 PF13479.6 CBZ33955.1 - 0.053 13.2 0.0 0.16 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CBZ33955.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 CBZ33955.1 - 0.08 12.0 0.2 0.22 10.6 0.1 1.7 1 1 1 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 CBZ33955.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FAM199X PF15814.5 CBZ33956.1 - 0.037 13.1 0.6 0.07 12.2 0.6 1.4 1 1 0 1 1 1 0 Protein family FAM199X ERM PF00769.19 CBZ33956.1 - 0.044 13.6 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TK PF00265.18 CBZ33957.1 - 1.4e-61 207.4 0.8 1.8e-61 207.1 0.8 1.1 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 CBZ33957.1 - 0.0018 18.3 0.0 0.0028 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Pox_A_type_inc PF04508.12 CBZ33958.1 - 0.039 13.8 6.7 0.89 9.5 0.9 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PKcGMP_CC PF16808.5 CBZ33958.1 - 0.32 10.9 17.0 0.04 13.8 0.9 5.8 4 1 1 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase WD40 PF00400.32 CBZ33959.1 - 5e-08 33.5 17.9 0.00014 22.6 0.2 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_3 PF13570.6 CBZ33959.1 - 0.005 17.3 9.6 0.1 13.1 0.1 4.9 7 0 0 7 7 7 2 PQQ-like domain ANAPC4_WD40 PF12894.7 CBZ33959.1 - 0.016 15.5 0.4 4.9 7.5 0.0 3.6 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2974 PF11187.8 CBZ33959.1 - 0.13 11.8 0.3 0.23 11.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) WD40_like PF17005.5 CBZ33959.1 - 0.18 11.1 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain WD40 PF00400.32 CBZ33960.1 - 2.3e-11 44.1 7.5 3.9e-06 27.5 0.1 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat RNR_N PF08343.10 CBZ33960.1 - 0.063 13.3 0.1 6.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal PQQ_3 PF13570.6 CBZ33960.1 - 0.17 12.4 0.8 26 5.5 0.1 4.1 5 0 0 5 5 5 0 PQQ-like domain ADK PF00406.22 CBZ33961.1 - 6.7e-39 133.4 0.0 1e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ33961.1 - 6.7e-18 65.4 0.0 1.8e-17 64.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBZ33961.1 - 1.1e-05 26.0 0.0 0.00011 22.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ33961.1 - 0.01 16.0 0.0 0.031 14.4 0.0 1.8 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.10 CBZ33961.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 LRR_6 PF13516.6 CBZ33962.1 - 5.3e-08 32.3 2.5 0.42 10.8 0.6 3.7 3 0 0 3 3 3 3 Leucine Rich repeat LRR_1 PF00560.33 CBZ33962.1 - 0.32 11.7 3.7 3.9 8.4 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 CBZ33962.1 - 0.73 9.6 3.9 14 5.5 2.1 3.0 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 CBZ33962.1 - 0.98 9.9 4.2 2 8.9 1.2 2.5 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Serine_rich PF08824.10 CBZ33963.1 - 0.0028 17.7 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Serine rich protein interaction domain Mito_fiss_reg PF05308.11 CBZ33963.1 - 0.081 13.0 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator SelR PF01641.18 CBZ33964.1 - 0.00011 22.2 0.1 0.034 14.2 0.0 2.4 2 0 0 2 2 2 2 SelR domain Synaptobrevin PF00957.21 CBZ33965.1 - 5.3e-26 90.2 0.4 8.4e-26 89.6 0.4 1.3 1 0 0 1 1 1 1 Synaptobrevin zf-RING_2 PF13639.6 CBZ33966.1 - 1.6e-10 41.1 3.5 2.7e-08 34.0 1.1 2.4 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 CBZ33966.1 - 6.3e-09 36.0 2.2 9.5e-08 32.2 0.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBZ33966.1 - 1.7e-08 34.1 2.9 2.4e-07 30.5 0.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBZ33966.1 - 9.2e-07 28.5 0.7 0.0034 17.1 0.1 2.5 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 CBZ33966.1 - 1.2e-06 28.3 2.6 5e-06 26.3 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CBZ33966.1 - 9.3e-05 22.4 0.2 0.0002 21.4 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CBZ33966.1 - 0.0051 16.6 3.1 0.029 14.2 0.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ33966.1 - 0.039 13.9 2.0 0.16 11.9 0.7 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.8 CBZ33966.1 - 0.04 13.7 0.4 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CBZ33966.1 - 0.074 13.1 8.2 0.12 12.4 1.8 2.9 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CBZ33966.1 - 0.079 13.1 1.5 0.079 13.1 1.5 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 CBZ33966.1 - 0.099 12.3 3.3 0.11 12.1 1.2 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 CBZ33966.1 - 0.15 11.9 0.4 0.15 11.9 0.4 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 CBZ33966.1 - 0.64 10.2 5.0 0.13 12.4 1.1 1.8 2 0 0 2 2 2 0 RING-variant domain Prok-RING_4 PF14447.6 CBZ33966.1 - 0.92 9.4 4.0 0.25 11.2 0.6 1.8 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 CBZ33966.1 - 2.8 8.2 4.8 8.8 6.6 2.6 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING-like PF08746.11 CBZ33966.1 - 3 8.2 4.7 0.99 9.8 1.7 1.7 2 0 0 2 2 1 0 RING-like domain RF-1 PF00472.20 CBZ33967.1 - 3.8e-09 36.5 1.0 3.8e-09 36.5 1.0 3.8 4 1 1 5 5 5 1 RF-1 domain KASH_CCD PF14662.6 CBZ33967.1 - 0.0016 18.3 10.1 0.0016 18.3 10.1 3.1 3 1 0 3 3 3 1 Coiled-coil region of CCDC155 or KASH DUF4250 PF14056.6 CBZ33967.1 - 0.021 14.7 2.6 0.14 12.2 0.5 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4250) Laminin_II PF06009.12 CBZ33967.1 - 1.7 8.6 15.2 0.56 10.2 9.8 3.0 2 1 0 2 2 2 0 Laminin Domain II LMBR1 PF04791.16 CBZ33967.1 - 2.8 6.8 4.0 5.3 5.8 4.0 1.5 1 0 0 1 1 1 0 LMBR1-like membrane protein Cep57_CLD_2 PF14197.6 CBZ33967.1 - 3.5 7.8 20.5 5.9 7.1 1.4 3.6 2 1 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF4201 PF13870.6 CBZ33967.1 - 4 7.1 28.3 0.037 13.8 5.4 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4201) DUF3390 PF11870.8 CBZ33968.1 - 0.021 15.2 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) SMC_N PF02463.19 CBZ33970.1 - 2e-68 230.1 12.0 2.5e-67 226.6 12.0 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBZ33970.1 - 5.7e-19 68.5 0.0 2.6e-18 66.4 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBZ33970.1 - 3.8e-12 46.6 0.3 3.5e-05 23.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ33970.1 - 3.1e-09 37.6 2.4 3.1e-09 37.6 2.4 6.2 3 2 2 5 5 5 1 AAA domain AAA_29 PF13555.6 CBZ33970.1 - 1.8e-05 24.4 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CBZ33970.1 - 0.00055 19.8 9.4 0.00055 19.8 9.4 3.3 2 1 0 2 2 2 1 AAA ATPase domain HlyE PF06109.13 CBZ33970.1 - 0.047 13.0 3.1 0.59 9.4 0.7 2.7 2 0 0 2 2 2 0 Haemolysin E (HlyE) DUF5398 PF17376.2 CBZ33970.1 - 0.17 12.5 0.1 0.17 12.5 0.1 4.1 3 1 0 3 3 3 0 Family of unknown function (DUF5398) ABC_tran PF00005.27 CBZ33970.1 - 0.28 11.7 0.0 0.28 11.7 0.0 5.2 6 1 0 6 6 6 0 ABC transporter AAA_22 PF13401.6 CBZ33970.1 - 2 8.7 0.0 2 8.7 0.0 4.5 4 3 1 5 5 5 0 AAA domain V-ATPase_H_N PF03224.14 CBZ33971.1 - 7.7e-72 242.2 0.1 1.1e-71 241.7 0.1 1.1 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CBZ33971.1 - 1.1e-35 122.3 0.0 5.2e-35 120.1 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H PB1 PF00564.24 CBZ33972.1 - 2.9e-08 33.5 0.0 8.6e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 PB1 domain DUF5433 PF17498.2 CBZ33974.1 - 1.3 9.3 2.9 3.1 8.1 2.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5433) DHHC PF01529.20 CBZ33976.1 - 3.2e-30 105.0 4.6 3.2e-30 105.0 4.6 2.6 3 1 0 3 3 3 1 DHHC palmitoyltransferase Herpes_UL73 PF03554.13 CBZ33976.1 - 0.14 12.2 2.0 0.37 10.8 2.0 1.8 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein DUF393 PF04134.12 CBZ33978.1 - 0.00089 20.6 2.5 0.034 15.5 0.4 2.6 2 1 0 2 2 2 2 Protein of unknown function, DUF393 Toxin_22 PF08092.11 CBZ33978.1 - 0.017 15.2 1.6 0.034 14.2 1.6 1.4 1 0 0 1 1 1 0 Magi peptide toxin family E1_dh PF00676.20 CBZ33979.1 - 1.3e-78 264.1 0.0 1.8e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4440 PF14534.6 CBZ33979.1 - 0.091 13.2 0.0 0.62 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) Cyt-b5 PF00173.28 CBZ33980.1 - 4.7e-05 23.5 0.0 0.00017 21.7 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Rad60-SLD PF11976.8 CBZ33980.1 - 0.016 15.1 0.0 0.055 13.3 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Metallothio_Cad PF07846.11 CBZ33980.1 - 0.041 14.0 0.1 0.074 13.2 0.1 1.4 1 0 0 1 1 1 0 Metallothionein family PRMT5 PF05185.16 CBZ33981.1 - 1.5e-39 135.7 0.0 2.5e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CBZ33981.1 - 8.1e-22 77.9 0.0 1.2e-21 77.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain TPR_2 PF07719.17 CBZ33983.1 - 3.1e-05 23.8 4.3 0.0002 21.2 0.4 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ33983.1 - 0.00044 20.2 3.1 0.3 11.4 0.6 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ33983.1 - 0.00094 18.9 3.3 0.0034 17.2 1.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ33983.1 - 0.0016 18.2 2.7 0.25 11.3 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ33983.1 - 0.0018 18.6 5.9 0.056 13.7 0.6 3.9 3 3 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ33983.1 - 0.0075 16.3 0.2 0.025 14.6 0.2 1.9 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 CBZ33983.1 - 0.019 15.0 0.1 0.019 15.0 0.1 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain CCB1 PF12046.8 CBZ33983.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B TPR_6 PF13174.6 CBZ33983.1 - 0.56 11.0 9.1 1.2 10.0 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ33983.1 - 0.61 10.6 5.2 1.9 9.1 0.3 3.5 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ33983.1 - 1.4 10.0 7.3 3.1 8.9 0.3 4.2 5 1 0 5 5 4 0 Tetratricopeptide repeat MAM33 PF02330.16 CBZ33984.1 - 0.0056 16.6 0.7 0.011 15.7 0.7 1.4 1 0 0 1 1 1 1 Mitochondrial glycoprotein ATP-synt_ab PF00006.25 CBZ33984.1 - 0.24 11.0 3.6 0.94 9.1 0.5 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HMG_box PF00505.19 CBZ33988.1 - 3.6e-07 30.5 4.9 0.01 16.2 1.6 3.9 2 2 1 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CBZ33988.1 - 5e-06 27.0 6.6 0.045 14.3 1.9 3.5 3 1 0 3 3 3 2 HMG-box domain HMG_box_5 PF14887.6 CBZ33988.1 - 0.13 12.3 1.3 0.58 10.2 0.2 2.6 2 1 0 2 2 2 0 HMG (high mobility group) box 5 DUF647 PF04884.14 CBZ33989.1 - 8.8e-69 231.8 1.3 1.3e-68 231.3 1.3 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Ribosomal_S17_N PF16205.5 CBZ33991.1 - 0.13 12.6 0.4 0.16 12.4 0.4 1.2 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal DEAD PF00270.29 CBZ33994.1 - 2.4e-36 125.1 0.3 1.4e-35 122.7 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ33994.1 - 1.5e-25 89.6 0.9 4e-25 88.3 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ33994.1 - 1.5e-08 34.8 0.0 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBZ33994.1 - 0.0007 19.0 0.1 0.008 15.6 0.0 2.6 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit DUF4844 PF16133.5 CBZ33994.1 - 0.016 15.8 1.1 0.042 14.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) LETM1 PF07766.13 CBZ33995.1 - 0.00073 19.0 0.1 0.0023 17.3 0.1 1.8 2 1 0 2 2 2 1 LETM1-like protein GST_C_6 PF17171.4 CBZ33996.1 - 1.4e-06 28.0 0.0 5.3e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF2537 PF10801.8 CBZ33996.1 - 0.039 14.2 2.0 0.13 12.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) COG6 PF06419.11 CBZ33997.1 - 0.11 10.7 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 GMC_oxred_C PF05199.13 CBZ33998.1 - 3.6e-13 50.3 0.1 2.5e-12 47.5 0.0 2.3 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CBZ33998.1 - 1.8e-11 43.9 0.0 2.6e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 CBZ33998.1 - 0.00035 19.9 0.2 0.034 13.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ33998.1 - 0.00043 19.5 0.0 0.011 14.8 0.1 2.9 4 0 0 4 4 4 1 Lycopene cyclase protein DAO PF01266.24 CBZ33998.1 - 0.0021 17.7 0.3 0.048 13.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ33998.1 - 0.0036 17.5 0.3 0.0036 17.5 0.3 3.0 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CBZ33998.1 - 0.0039 16.0 0.3 0.006 15.3 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 CBZ33998.1 - 0.0067 15.5 0.1 0.015 14.4 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CBZ33998.1 - 0.027 13.7 0.4 0.027 13.7 0.4 2.2 3 0 0 3 3 3 0 Thi4 family Pkinase PF00069.25 CBZ33999.1 - 1.2e-63 214.9 0.0 2e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ33999.1 - 3.4e-44 151.1 0.0 5.8e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ33999.1 - 4.2e-05 23.0 0.0 4.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like MIP-T3_C PF17749.1 CBZ34000.1 - 2.2e-53 180.4 2.5 2.2e-53 180.4 2.5 3.0 3 1 0 3 3 3 1 Microtubule-binding protein MIP-T3 C-terminal region MIP-T3 PF10243.9 CBZ34000.1 - 1.8e-49 166.4 0.3 6e-49 164.7 0.1 2.0 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain UPF0242 PF06785.11 CBZ34000.1 - 0.83 9.7 13.6 0.055 13.6 1.5 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus COMP PF11598.8 CBZ34000.1 - 1.8 9.1 5.8 1.2 9.7 1.4 2.6 2 1 0 2 2 2 0 Cartilage oligomeric matrix protein Nup88 PF10168.9 CBZ34000.1 - 5.5 4.7 10.2 0.11 10.3 3.3 1.5 2 0 0 2 2 2 0 Nuclear pore component CK2S PF15011.6 CBZ34001.1 - 0.087 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate peroxidase PF00141.23 CBZ34002.1 - 1e-09 38.5 0.0 1.3e-08 34.8 0.0 2.2 1 1 0 2 2 2 1 Peroxidase WD40 PF00400.32 CBZ34003.1 - 0.024 15.5 4.2 2.7 9.0 0.1 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ34003.1 - 0.079 13.3 0.1 0.82 10.0 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Chordopox_A13L PF05961.11 CBZ34004.1 - 7.5 6.9 6.5 0.4 11.0 0.2 2.3 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Nodulin-like PF06813.13 CBZ34005.1 - 2.8e-05 23.7 10.0 2.8e-05 23.7 10.0 2.6 3 0 0 3 3 3 1 Nodulin-like PGG PF13962.6 CBZ34005.1 - 0.014 15.2 0.5 0.014 15.2 0.5 4.1 5 1 0 5 5 5 0 Domain of unknown function MFS_1 PF07690.16 CBZ34005.1 - 0.79 8.6 54.7 0.016 14.2 30.0 3.2 2 1 0 2 2 2 0 Major Facilitator Superfamily F-box-like PF12937.7 CBZ34006.1 - 2.3e-07 30.6 0.5 5.5e-07 29.4 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CBZ34006.1 - 1.1e-06 28.3 0.7 3.4e-06 26.8 0.4 2.0 2 0 0 2 2 2 1 F-box domain DUF2207 PF09972.9 CBZ34006.1 - 0.64 8.7 0.0 0.64 8.7 0.0 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF5079 PF16882.5 CBZ34006.1 - 3 7.6 11.9 0.67 9.8 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5079) DUF3782 PF12644.7 CBZ34007.1 - 0.26 11.5 3.8 20 5.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3782) zf-Sec23_Sec24 PF04810.15 CBZ34008.1 - 0.002 18.1 0.5 0.02 15.0 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger HpaB PF03241.13 CBZ34008.1 - 0.032 13.3 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal P3A PF08727.11 CBZ34008.1 - 0.077 12.4 0.5 12 5.3 0.0 2.5 2 1 0 2 2 2 0 Poliovirus 3A protein like Rad60-SLD_2 PF13881.6 CBZ34009.1 - 1.1e-05 25.5 2.3 0.00016 21.8 2.3 2.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CBZ34009.1 - 0.00028 21.4 0.0 0.00048 20.6 0.0 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain PPR_2 PF13041.6 CBZ34010.1 - 2.6e-07 30.7 0.3 6.9e-07 29.4 0.1 1.9 2 0 0 2 2 2 1 PPR repeat family PPR_3 PF13812.6 CBZ34010.1 - 3.9e-05 23.6 0.1 7.9e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR PF01535.20 CBZ34010.1 - 0.0046 17.1 0.6 0.017 15.3 0.0 2.3 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 CBZ34010.1 - 0.044 13.1 0.1 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP CKS PF01111.19 CBZ34010.1 - 0.15 12.3 0.4 0.72 10.2 0.2 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit EF-hand_1 PF00036.32 CBZ34011.1 - 8.5e-24 81.3 8.8 2.6e-06 26.6 0.3 4.5 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CBZ34011.1 - 2.1e-21 76.1 6.7 1.3e-12 47.9 1.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CBZ34011.1 - 2.5e-19 67.5 7.7 6.7e-05 22.5 0.3 4.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CBZ34011.1 - 5.5e-16 57.3 13.1 1e-06 27.9 0.2 5.0 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 CBZ34011.1 - 2.6e-11 43.2 7.9 0.0003 20.6 1.4 4.1 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CBZ34011.1 - 4.7e-07 29.7 2.7 0.32 11.0 0.2 3.5 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CBZ34011.1 - 4.6e-06 26.9 0.0 0.017 15.5 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CBZ34011.1 - 6.1e-05 23.1 0.8 0.0019 18.4 0.8 2.6 2 1 0 2 2 2 1 Dockerin type I domain DUF1425 PF07233.12 CBZ34011.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) DUF3349 PF11829.8 CBZ34011.1 - 0.16 12.8 0.1 21 6.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) TetR_C_31 PF17940.1 CBZ34012.1 - 0.035 14.3 0.3 0.13 12.5 0.0 2.1 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 CBZ34013.1 - 6.2e-40 137.2 0.0 7.8e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34013.1 - 5.1e-10 39.1 0.0 7.8e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase 5_3_exonuc_N PF02739.16 CBZ34014.1 - 1e-26 93.8 0.1 1.4e-26 93.3 0.1 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 CBZ34014.1 - 1.8e-19 70.1 0.0 3.5e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold EspB_PE PF18625.1 CBZ34014.1 - 0.0093 16.4 0.0 0.025 15.1 0.0 1.7 2 0 0 2 2 2 1 ESX-1 secreted protein B PE domain DUF3361 PF11841.8 CBZ34015.1 - 0.049 13.6 0.1 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) zf-MYND PF01753.18 CBZ34016.1 - 0.002 18.1 20.3 0.0035 17.4 20.3 1.4 1 0 0 1 1 1 1 MYND finger SlyX PF04102.12 CBZ34016.1 - 0.11 13.2 0.3 0.21 12.2 0.3 1.5 1 0 0 1 1 1 0 SlyX PUF PF00806.19 CBZ34017.1 - 1.1e-51 169.7 4.6 5.3e-06 25.8 0.0 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 CBZ34017.1 - 0.0019 18.6 0.4 9.7 6.5 0.0 3.8 2 1 2 4 4 4 3 CPL (NUC119) domain HrpB1_HrpK PF09613.10 CBZ34017.1 - 0.017 14.8 0.6 1 9.0 0.1 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) MCU PF04678.13 CBZ34018.1 - 1.4e-31 110.0 1.3 1.9e-31 109.5 0.8 1.4 1 1 0 1 1 1 1 Mitochondrial calcium uniporter DNA_PPF PF02916.15 CBZ34018.1 - 0.088 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase processivity factor Proteasome PF00227.26 CBZ34019.1 - 1.7e-65 220.1 0.0 2.3e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ34019.1 - 6.5e-09 35.3 0.6 3.6e-08 32.9 0.1 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature YadA_head PF05658.14 CBZ34019.1 - 4.3 7.9 6.6 15 6.1 1.6 2.3 2 0 0 2 2 2 0 Head domain of trimeric autotransporter adhesin DUF4874 PF16173.5 CBZ34020.1 - 0.18 11.5 0.4 0.25 11.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Ribosomal_L32e PF01655.18 CBZ34021.1 - 9.5e-39 132.2 0.1 1.2e-38 131.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 PMSI1 PF15322.6 CBZ34022.1 - 0.35 10.3 3.8 1.1 8.6 0.1 2.0 1 1 0 2 2 2 0 Protein missing in infertile sperm 1, putative Wbp11 PF09429.10 CBZ34022.1 - 0.69 10.3 14.6 0.18 12.2 11.2 1.8 2 0 0 2 2 2 0 WW domain binding protein 11 LCD1 PF09798.9 CBZ34022.1 - 1.2 7.6 6.1 1.4 7.4 6.1 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein PAP_assoc PF03828.19 CBZ34023.1 - 4.8e-05 23.5 0.1 0.00013 22.1 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase SET PF00856.28 CBZ34024.1 - 6.3e-06 26.7 0.4 0.00042 20.7 0.4 2.4 1 1 0 1 1 1 1 SET domain PHD PF00628.29 CBZ34024.1 - 0.047 13.6 10.8 0.17 11.8 10.8 2.1 1 1 0 1 1 1 0 PHD-finger DUF4154 PF13689.6 CBZ34024.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.7 1 1 1 2 2 2 0 YfiR/HmsC-like FYVE PF01363.21 CBZ34024.1 - 0.29 11.3 8.3 0.95 9.6 8.3 1.9 1 0 0 1 1 1 0 FYVE zinc finger DKCLD PF08068.12 CBZ34025.1 - 1.2e-31 108.5 0.0 2e-30 104.6 0.1 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 CBZ34025.1 - 4.2e-22 79.1 2.5 2.3e-15 57.2 0.4 3.3 1 1 1 2 2 2 2 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 CBZ34025.1 - 1.4e-20 73.0 0.9 2.7e-20 72.1 0.9 1.5 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 CBZ34025.1 - 2.8e-20 72.2 0.5 5.2e-20 71.4 0.5 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 CBZ34025.1 - 0.0085 16.3 0.0 0.033 14.4 0.0 2.0 2 0 0 2 2 2 1 UPF0113 PUA domain PseudoU_synth_2 PF00849.22 CBZ34025.1 - 0.081 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA pseudouridylate synthase ATP-synt PF00231.19 CBZ34026.1 - 4.9e-51 174.1 1.1 5.5e-51 173.9 1.1 1.0 1 0 0 1 1 1 1 ATP synthase ATP-synt_C PF00137.21 CBZ34027.1 - 1.2e-26 92.7 33.7 1.7e-19 69.9 14.2 2.7 3 0 0 3 3 3 2 ATP synthase subunit C GerA PF03323.13 CBZ34027.1 - 0.29 9.5 3.6 2.9 6.3 0.7 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein ATP-synt_C PF00137.21 CBZ34028.1 - 2.3e-09 37.4 11.5 2.3e-09 37.4 11.5 1.8 2 0 0 2 2 2 1 ATP synthase subunit C AcrZ PF10766.9 CBZ34028.1 - 0.19 11.3 3.3 0.46 10.1 3.3 1.6 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ Gaa1 PF04114.14 CBZ34029.1 - 1.2e-07 31.2 0.2 1.2e-07 31.2 0.2 2.5 2 1 1 3 3 3 1 Gaa1-like, GPI transamidase component Ribosomal_L37ae PF01780.19 CBZ34030.1 - 9.2e-37 125.0 4.5 1e-36 124.9 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.22 CBZ34030.1 - 0.0022 17.8 2.3 0.0032 17.3 2.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_13 PF17977.1 CBZ34030.1 - 0.05 13.7 1.1 0.071 13.2 1.1 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CBZ34030.1 - 0.065 13.2 2.3 0.11 12.5 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 CBZ34030.1 - 0.16 12.2 3.8 0.43 10.8 0.6 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Proteasome PF00227.26 CBZ34031.1 - 1.3e-58 197.6 0.0 1.6e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ34031.1 - 3.4e-13 49.0 0.0 1e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pex14_N PF04695.13 CBZ34032.1 - 1.2e-25 91.0 1.3 1.2e-25 91.0 1.3 3.7 2 1 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Rootletin PF15035.6 CBZ34032.1 - 7.3e-07 29.4 0.2 1.1e-06 28.8 0.2 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 CBZ34032.1 - 0.00036 21.1 0.3 0.00062 20.3 0.3 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region GAS PF13851.6 CBZ34032.1 - 0.00045 19.6 2.9 0.00071 19.0 2.9 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding ERM PF00769.19 CBZ34032.1 - 0.007 16.2 9.0 0.012 15.5 9.0 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF5082 PF16888.5 CBZ34032.1 - 0.007 16.6 2.9 0.44 10.8 1.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) CC2-LZ PF16516.5 CBZ34032.1 - 0.0071 16.7 4.0 0.014 15.8 4.0 1.4 1 0 0 1 1 1 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FAM76 PF16046.5 CBZ34032.1 - 0.0086 15.5 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 FAM76 protein LOH1CR12 PF10158.9 CBZ34032.1 - 0.016 15.3 0.3 0.026 14.6 0.3 1.3 1 0 0 1 1 1 0 Tumour suppressor protein Fez1 PF06818.15 CBZ34032.1 - 0.019 15.4 0.4 0.029 14.8 0.4 1.2 1 0 0 1 1 1 0 Fez1 GIT_CC PF16559.5 CBZ34032.1 - 0.021 14.6 1.7 0.14 12.0 0.3 2.5 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 CBZ34032.1 - 0.034 14.2 0.6 0.066 13.3 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) JAKMIP_CC3 PF16034.5 CBZ34032.1 - 0.037 14.0 1.4 0.068 13.1 1.4 1.4 1 0 0 1 1 1 0 JAKMIP CC3 domain CALCOCO1 PF07888.11 CBZ34032.1 - 0.039 12.8 5.1 0.059 12.2 5.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cep57_CLD_2 PF14197.6 CBZ34032.1 - 0.054 13.6 5.4 0.32 11.1 0.7 2.3 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 HOOK PF05622.12 CBZ34032.1 - 0.061 11.5 2.9 0.085 11.0 2.9 1.1 1 0 0 1 1 1 0 HOOK protein Macoilin PF09726.9 CBZ34032.1 - 0.071 11.7 0.1 0.099 11.2 0.1 1.1 1 0 0 1 1 1 0 Macoilin family KASH_CCD PF14662.6 CBZ34032.1 - 0.095 12.5 4.5 0.16 11.7 4.5 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Siah-Interact_N PF09032.11 CBZ34032.1 - 0.14 12.5 8.3 0.85 10.0 0.1 3.1 2 1 1 3 3 2 0 Siah interacting protein, N terminal BLOC1_2 PF10046.9 CBZ34032.1 - 0.16 12.3 1.0 0.31 11.4 1.0 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HBM PF16591.5 CBZ34032.1 - 0.17 11.3 4.3 0.29 10.5 4.3 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain FlxA PF14282.6 CBZ34032.1 - 0.17 11.9 6.0 0.94 9.5 6.0 2.1 1 1 0 1 1 1 0 FlxA-like protein CENP-H PF05837.12 CBZ34032.1 - 0.17 12.3 6.6 0.34 11.3 6.6 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FapA PF03961.13 CBZ34032.1 - 0.17 10.4 1.3 0.25 9.9 1.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Spc7 PF08317.11 CBZ34032.1 - 0.5 9.2 5.3 0.77 8.6 5.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 CBZ34032.1 - 0.5 9.9 5.5 0.74 9.3 5.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.8 CBZ34032.1 - 0.52 9.6 6.3 0.94 8.7 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RRF PF01765.19 CBZ34032.1 - 0.53 10.2 5.3 0.92 9.4 5.3 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF2968 PF11180.8 CBZ34032.1 - 0.53 9.9 6.7 1.1 8.9 6.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) G-gamma PF00631.22 CBZ34032.1 - 0.54 10.3 3.3 1.8 8.6 0.2 2.4 2 0 0 2 2 2 0 GGL domain Snapin_Pallidin PF14712.6 CBZ34032.1 - 0.55 10.7 3.2 1.2 9.7 2.9 1.7 1 1 0 1 1 1 0 Snapin/Pallidin ATG16 PF08614.11 CBZ34032.1 - 0.57 10.4 11.7 3.5 7.8 10.4 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) NuDC PF16273.5 CBZ34032.1 - 0.61 10.7 6.5 0.45 11.1 4.4 1.8 1 1 0 1 1 1 0 Nuclear distribution C domain AAA_13 PF13166.6 CBZ34032.1 - 0.74 8.4 2.4 1 7.9 2.4 1.1 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 CBZ34032.1 - 1.1 8.3 4.6 2.2 7.3 4.6 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMCO5 PF14992.6 CBZ34032.1 - 1.1 8.7 5.0 2.2 7.8 5.0 1.4 1 1 0 1 1 1 0 TMCO5 family ADIP PF11559.8 CBZ34032.1 - 1.7 8.7 8.3 3.7 7.6 8.1 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding PRKG1_interact PF15898.5 CBZ34032.1 - 2.2 9.2 7.3 7.4 7.5 7.3 1.9 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain TMF_TATA_bd PF12325.8 CBZ34032.1 - 3.2 8.0 7.6 9 6.5 5.2 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fungal_TACC PF12709.7 CBZ34032.1 - 4.1 7.9 5.4 1.9 9.0 0.6 2.1 1 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF1192 PF06698.11 CBZ34032.1 - 5.4 7.1 8.6 19 5.4 1.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF3584 PF12128.8 CBZ34032.1 - 6 4.2 8.3 8.3 3.8 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DivIC PF04977.15 CBZ34032.1 - 6.2 6.7 10.3 0.59 9.9 2.6 2.3 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 CBZ34032.1 - 7.2 7.1 9.1 23 5.5 0.9 2.3 1 1 1 2 2 2 0 Cell division protein ZapB DUF4407 PF14362.6 CBZ34032.1 - 7.7 5.8 10.7 21 4.3 10.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 CBZ34032.1 - 7.9 6.6 9.3 4.1 7.5 1.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.6 CBZ34032.1 - 9.4 6.4 9.4 69 3.6 9.3 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_1 PF00170.21 CBZ34032.1 - 9.5 6.4 8.9 2.1 8.5 0.2 2.6 2 1 1 3 3 2 0 bZIP transcription factor BolA PF01722.18 CBZ34034.1 - 3.7e-17 62.4 0.0 1.1e-16 60.9 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Tubulin PF00091.25 CBZ34035.1 - 1.1e-17 64.9 0.0 1.2e-17 64.8 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Misat_Tub_SegII PF10644.9 CBZ34035.1 - 1.8e-06 28.3 0.0 2.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Ribosomal_L5_C PF00673.21 CBZ34037.1 - 4.7e-21 74.8 0.0 7.8e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CBZ34037.1 - 5.4e-18 65.1 0.2 1.1e-16 60.8 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L5 SET PF00856.28 CBZ34038.1 - 1.2e-05 25.8 0.0 1.6e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 SET domain R3H PF01424.22 CBZ34040.1 - 5.1e-12 45.6 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CBZ34040.1 - 2.9e-11 43.2 60.0 6.1e-06 26.2 14.2 14.6 15 1 1 16 16 16 8 NF-X1 type zinc finger HopA1 PF17914.1 CBZ34040.1 - 0.024 14.4 0.1 2.6 7.8 0.0 2.6 1 1 1 2 2 2 0 HopA1 effector protein family Rad10 PF03834.14 CBZ34041.1 - 0.0009 19.3 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DnaJ_C PF01556.18 CBZ34042.1 - 3.3e-35 121.3 0.0 4.3e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CBZ34042.1 - 7.9e-15 55.0 12.8 2e-14 53.7 12.8 1.7 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ34042.1 - 7.6e-06 25.8 13.5 0.0071 16.3 4.6 2.4 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CBZ34042.1 - 0.0016 18.4 7.6 0.15 12.1 0.2 2.8 2 1 1 3 3 3 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 CBZ34042.1 - 0.055 13.1 2.1 0.094 12.4 2.1 1.3 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 DUF3556 PF12077.8 CBZ34042.1 - 0.11 10.9 0.1 0.15 10.5 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) zinc-ribbons_6 PF07191.12 CBZ34042.1 - 1.8 8.6 7.7 47 4.1 0.5 2.5 1 1 1 2 2 2 0 zinc-ribbons zf_CopZ PF18423.1 CBZ34042.1 - 3.7 7.6 6.1 3.8 7.6 0.1 3.2 2 1 1 3 3 3 0 Zinc binding domain FdhE PF04216.12 CBZ34042.1 - 4.5 7.1 6.0 7.8 6.3 6.0 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation DUF1356 PF07092.12 CBZ34042.1 - 9.7 5.4 6.5 25 4.0 0.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1356) Pox_MCEL PF03291.16 CBZ34043.1 - 1.7e-46 158.9 0.0 2.2e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme mRNA_cap_C PF03919.15 CBZ34043.1 - 2.7e-08 34.4 0.0 7.9e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain mRNA_cap_enzyme PF01331.19 CBZ34043.1 - 7.4e-08 32.4 0.0 0.009 15.8 0.0 2.4 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain Methyltransf_25 PF13649.6 CBZ34043.1 - 3.7e-06 27.5 0.2 0.00032 21.3 0.1 3.5 2 1 0 2 2 2 1 Methyltransferase domain GATase PF00117.28 CBZ34045.1 - 1.4e-37 129.4 0.0 3.2e-37 128.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 CBZ34045.1 - 7.2e-17 61.2 0.0 9.8e-08 32.0 0.0 3.3 3 0 0 3 3 3 2 GMP synthase C terminal domain Peptidase_C26 PF07722.13 CBZ34045.1 - 5.2e-14 52.5 0.0 2.5e-13 50.3 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 CBZ34045.1 - 2.9e-09 36.4 0.1 0.00032 19.9 0.1 2.4 2 0 0 2 2 2 2 NAD synthase QueC PF06508.13 CBZ34045.1 - 2.7e-05 23.8 0.0 0.0002 20.9 0.0 2.1 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 CBZ34045.1 - 0.00017 21.2 0.1 0.0011 18.6 0.1 2.3 3 0 0 3 3 3 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 CBZ34045.1 - 0.0022 18.0 0.0 0.0039 17.2 0.0 1.5 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 CBZ34045.1 - 0.0059 15.9 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase GATase_3 PF07685.14 CBZ34045.1 - 0.006 16.2 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ATP_bind_3 PF01171.20 CBZ34045.1 - 0.007 16.1 0.1 0.029 14.1 0.1 2.0 2 0 0 2 2 2 1 PP-loop family tRNA_Me_trans PF03054.16 CBZ34045.1 - 0.016 14.1 0.1 0.058 12.2 0.1 1.8 2 0 0 2 2 2 0 tRNA methyl transferase GP79 PF17463.2 CBZ34045.1 - 0.13 12.2 0.3 0.33 11.0 0.3 1.6 1 0 0 1 1 1 0 Gene product 79 Tup_N PF08581.10 CBZ34046.1 - 0.00012 22.4 15.3 0.00039 20.7 0.6 3.1 2 1 1 3 3 3 2 Tup N-terminal Med20 PF08612.11 CBZ34046.1 - 0.055 12.8 0.3 0.12 11.8 0.3 1.5 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex NRN1 PF15056.6 CBZ34046.1 - 0.41 10.8 3.5 0.37 10.9 0.3 2.4 2 1 0 2 2 2 0 Neuritin protein family DUF1664 PF07889.12 CBZ34046.1 - 1.5 8.9 12.3 0.2 11.7 5.8 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 CBZ34046.1 - 1.9 8.3 9.7 0.89 9.4 4.2 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4726 PF15855.5 CBZ34046.1 - 4.5 7.6 6.1 0.53 10.5 0.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4726) FlaC_arch PF05377.11 CBZ34046.1 - 5.4 7.5 11.5 6.8 7.2 1.5 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ZnuA PF01297.17 CBZ34046.1 - 6.8 6.0 8.5 2.5 7.5 1.2 2.3 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Allexi_40kDa PF05549.11 CBZ34046.1 - 8.3 5.8 10.1 4.5 6.7 7.1 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein Spc7 PF08317.11 CBZ34046.1 - 8.5 5.2 34.0 1 8.2 21.8 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein BAG PF02179.16 CBZ34047.1 - 1.7e-05 25.1 0.3 3.4e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 BAG domain Dcc1 PF09724.9 CBZ34048.1 - 6.2e-53 180.3 0.0 7.1e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 XPC-binding PF09280.11 CBZ34048.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 XPC-binding domain zf-CCCH_4 PF18044.1 CBZ34049.1 - 3.4e-09 36.3 11.0 7.1e-05 22.5 2.5 3.2 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CBZ34049.1 - 5.5e-06 27.0 1.0 0.083 13.6 0.3 2.7 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 CBZ34049.1 - 1.3e-05 25.0 1.8 1.3e-05 25.0 1.8 3.7 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ34049.1 - 0.0013 18.7 14.3 0.0038 17.2 2.9 3.5 4 0 0 4 4 4 2 Zinc finger domain DUF883 PF05957.13 CBZ34051.1 - 0.00028 21.4 17.7 0.019 15.5 5.9 3.2 1 1 2 3 3 3 3 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 CBZ34051.1 - 0.00083 19.3 17.7 0.0064 16.4 16.2 2.6 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain ApoO PF09769.9 CBZ34051.1 - 0.0026 17.7 7.6 0.11 12.4 1.4 3.1 1 1 1 2 2 2 2 Apolipoprotein O Mitofilin PF09731.9 CBZ34051.1 - 0.0036 16.2 14.6 0.0042 16.0 14.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ApoLp-III PF07464.11 CBZ34051.1 - 0.0083 16.2 22.0 0.05 13.7 7.2 3.0 2 1 1 3 3 3 2 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 CBZ34051.1 - 0.031 14.3 8.2 0.1 12.7 0.2 3.0 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 CBZ34051.1 - 0.041 13.4 6.7 0.065 12.7 6.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF842 PF05811.13 CBZ34051.1 - 0.097 12.4 3.7 0.3 10.8 3.7 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) TPR_MLP1_2 PF07926.12 CBZ34051.1 - 0.11 12.6 15.3 0.049 13.7 12.1 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein RRF PF01765.19 CBZ34051.1 - 0.18 11.7 16.4 0.97 9.4 2.3 3.7 2 1 2 4 4 4 0 Ribosome recycling factor ATG_C PF09333.11 CBZ34051.1 - 0.21 12.0 15.7 0.28 11.5 1.0 3.6 2 1 1 4 4 4 0 Autophagy-related protein C terminal domain BAR_3 PF16746.5 CBZ34051.1 - 0.29 10.8 3.6 0.53 10.0 3.6 1.5 1 0 0 1 1 1 0 BAR domain of APPL family Glycophorin_A PF01102.18 CBZ34051.1 - 0.43 10.8 7.0 0.046 14.0 1.0 2.2 2 1 0 2 2 2 0 Glycophorin A HisKA_3 PF07730.13 CBZ34051.1 - 0.85 10.2 6.9 20 5.8 0.1 3.6 1 1 2 3 3 3 0 Histidine kinase DUF357 PF04010.13 CBZ34051.1 - 0.96 9.6 3.4 7.3 6.7 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF357) Spc7 PF08317.11 CBZ34051.1 - 1.1 8.0 9.0 2.9 6.7 4.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ISG65-75 PF11727.8 CBZ34051.1 - 1.3 8.2 20.9 2.4 7.3 15.8 2.3 1 1 1 2 2 2 0 Invariant surface glycoprotein DUF1451 PF07295.11 CBZ34051.1 - 2 8.5 8.0 3.3 7.7 2.0 2.6 1 1 1 2 2 2 0 Zinc-ribbon containing domain Mit_KHE1 PF10173.9 CBZ34051.1 - 2.2 8.3 5.7 8.5 6.4 5.7 2.0 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF745 PF05335.13 CBZ34051.1 - 3.1 7.5 30.8 0.22 11.2 23.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF745) SCAB_CC PF16712.5 CBZ34051.1 - 3.2 7.6 15.5 2.3 8.0 10.2 2.8 1 1 2 3 3 3 0 Coiled-coil regions of plant-specific actin-binding protein DivIVA PF05103.13 CBZ34051.1 - 3.2 7.8 19.4 1.1 9.3 9.8 3.3 2 1 1 3 3 2 0 DivIVA protein YtxH PF12732.7 CBZ34051.1 - 3.4 8.3 19.0 7.2e+03 -2.4 17.5 3.8 2 1 0 2 2 0 0 YtxH-like protein Syntaxin-6_N PF09177.11 CBZ34051.1 - 3.6 8.2 7.5 70 4.1 7.5 2.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ZYG-11_interact PF05884.12 CBZ34051.1 - 4.4 6.6 9.1 13 5.1 8.1 2.0 1 1 1 2 2 2 0 Interactor of ZYG-11 dCache_2 PF08269.11 CBZ34051.1 - 4.4 6.4 9.3 21 4.2 9.2 2.0 1 1 0 1 1 1 0 Cache domain DUF2564 PF10819.8 CBZ34051.1 - 7.7 7.0 21.8 0.84 10.1 3.2 4.4 2 2 3 5 5 5 0 Protein of unknown function (DUF2564) KfrA_N PF11740.8 CBZ34051.1 - 7.9 7.2 21.3 24 5.6 17.5 2.7 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term Phasin PF05597.11 CBZ34051.1 - 8.6 6.4 17.4 1.5 8.8 2.3 3.4 1 1 2 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Metal_resist PF13801.6 CBZ34052.1 - 0.092 12.9 0.1 0.092 12.9 0.1 1.9 2 0 0 2 2 2 0 Heavy-metal resistance zf-RING_10 PF16685.5 CBZ34052.1 - 0.39 10.9 15.0 0.34 11.1 10.5 2.6 1 1 1 2 2 2 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 CBZ34052.1 - 0.63 10.1 18.3 2.3 8.3 10.7 3.5 2 1 0 2 2 2 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ34052.1 - 0.75 9.7 16.0 3.7 7.5 14.8 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ34052.1 - 5.8 6.8 18.7 0.2 11.5 11.9 2.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF1736 PF08409.11 CBZ34054.1 - 1.2e-17 63.6 0.2 5e-17 61.7 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_17 PF13431.6 CBZ34054.1 - 0.0045 17.3 0.2 0.95 10.0 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat Aa_trans PF01490.18 CBZ34055.1 - 5.4e-61 206.5 31.5 6.3e-61 206.3 31.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ34055.1 - 7.5e-06 25.2 11.4 7.5e-06 25.2 11.4 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Y_phosphatase3 PF13350.6 CBZ34057.1 - 6.6e-57 193.1 0.0 7.4e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 CBZ34057.1 - 0.007 16.0 0.0 0.022 14.3 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBZ34057.1 - 0.026 14.1 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 CBZ34057.1 - 0.029 14.2 0.0 0.052 13.4 0.0 1.5 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBZ34057.1 - 0.067 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate TRAP_alpha PF03896.16 CBZ34058.1 - 5.5e-18 65.2 0.1 6.5e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit PAP2_3 PF14378.6 CBZ34058.1 - 0.00094 18.9 0.0 0.002 17.9 0.0 1.5 2 0 0 2 2 2 1 PAP2 superfamily zf-Tim10_DDP PF02953.15 CBZ34059.1 - 4.9e-12 45.3 2.3 5.7e-12 45.1 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mito_carr PF00153.27 CBZ34062.1 - 1.7e-08 34.3 0.5 1.6e-06 27.9 0.1 3.2 3 0 0 3 3 3 1 Mitochondrial carrier protein BP28CT PF08146.12 CBZ34063.1 - 0.14 12.0 0.7 0.31 10.9 0.1 1.9 2 0 0 2 2 2 0 BP28CT (NUC211) domain Carn_acyltransf PF00755.20 CBZ34064.1 - 2.5e-87 293.9 0.0 3.2e-87 293.6 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SEP PF08059.13 CBZ34065.1 - 1.6e-15 57.4 0.0 4.6e-15 55.9 0.0 1.9 1 0 0 1 1 1 1 SEP domain CUE PF02845.16 CBZ34065.1 - 0.0009 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 CBZ34065.1 - 0.012 15.4 0.1 0.026 14.3 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain THF_DHG_CYH_C PF02882.19 CBZ34067.1 - 4.2e-30 104.2 0.6 1.7e-28 98.9 0.4 2.5 3 0 0 3 3 3 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBZ34067.1 - 2.8e-26 92.1 0.0 5e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Macoilin PF09726.9 CBZ34068.1 - 0.019 13.5 4.8 0.023 13.3 4.8 1.0 1 0 0 1 1 1 0 Macoilin family MscS_porin PF12795.7 CBZ34068.1 - 0.12 11.9 13.3 0.16 11.5 13.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF1663 PF07909.11 CBZ34069.1 - 0.55 8.9 6.6 1 8.0 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) DNA_primase_S PF01896.19 CBZ34072.1 - 6.5e-42 143.6 0.2 1.3e-41 142.6 0.2 1.5 1 1 0 1 1 1 1 DNA primase small subunit cNMP_binding PF00027.29 CBZ34073.1 - 0.0002 21.4 0.0 6.4 6.9 0.0 3.9 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain AAA_25 PF13481.6 CBZ34073.1 - 0.075 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain Ephrin_rec_like PF07699.13 CBZ34074.1 - 1.1e-05 25.0 19.3 0.00028 20.6 4.2 9.5 6 3 3 9 9 9 5 Putative ephrin-receptor like Serglycin PF04360.12 CBZ34074.1 - 0.12 12.3 2.9 0.35 10.8 2.9 1.7 1 0 0 1 1 1 0 Serglycin NCD3G PF07562.14 CBZ34074.1 - 0.77 9.8 50.5 0.023 14.7 5.2 7.2 6 3 0 7 7 7 0 Nine Cysteines Domain of family 3 GPCR Ribosomal_S19 PF00203.21 CBZ34076.1 - 3.1e-29 100.7 0.4 3.6e-29 100.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 PmbA_TldD PF01523.16 CBZ34076.1 - 0.038 13.9 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase FlaC_arch PF05377.11 CBZ34077.1 - 0.057 13.8 0.3 1.1 9.8 0.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Rhabdo_M1 PF03342.13 CBZ34077.1 - 0.43 9.9 2.7 0.74 9.1 1.8 1.8 1 1 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Acetyltransf_1 PF00583.25 CBZ34078.1 - 8.5e-11 42.1 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBZ34078.1 - 7.8e-07 29.4 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBZ34078.1 - 0.00018 21.4 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CBZ34078.1 - 0.00031 20.7 0.0 0.00058 19.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CBZ34078.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA_bind PF01588.20 CBZ34080.1 - 1e-24 86.5 0.1 2.1e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain Dynamin_N PF00350.23 CBZ34081.1 - 5.3e-13 49.4 0.0 2.6e-12 47.1 0.0 2.0 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CBZ34081.1 - 3.2e-09 36.9 0.0 1.4e-08 34.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ34081.1 - 0.00074 19.5 0.6 0.11 12.4 0.5 3.1 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 CBZ34081.1 - 0.0018 17.8 0.0 0.31 10.5 0.0 2.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 CBZ34081.1 - 0.0099 16.1 0.0 1.7 8.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CBZ34081.1 - 0.023 14.2 0.1 0.8 9.2 0.0 2.7 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CBZ34081.1 - 0.082 13.4 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.20 CBZ34081.1 - 0.15 11.2 0.5 10 5.1 0.1 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Pyr_redox PF00070.27 CBZ34081.1 - 0.16 12.5 0.0 0.4 11.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Peptidase_C7 PF01830.18 CBZ34082.1 - 0.048 13.1 0.8 0.93 8.9 0.1 2.1 1 1 1 2 2 2 0 Peptidase C7 family Med26 PF08711.11 CBZ34083.1 - 4.4e-05 23.4 9.1 0.01 15.8 0.0 3.4 3 0 0 3 3 3 3 TFIIS helical bundle-like domain RabGAP-TBC PF00566.18 CBZ34085.1 - 4.2e-33 114.8 0.0 6.3e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain T7SS_ESX_EspC PF10824.8 CBZ34085.1 - 1.5 9.4 11.4 0.065 13.7 2.6 3.2 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Rotamase PF00639.21 CBZ34086.1 - 8.5e-14 52.3 0.0 1.7e-13 51.4 0.0 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CBZ34086.1 - 1.9e-09 38.0 0.0 3.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CBZ34086.1 - 0.0002 22.2 0.1 0.00051 20.9 0.0 1.6 2 0 0 2 2 2 1 PPIC-type PPIASE domain PPR PF01535.20 CBZ34087.1 - 0.033 14.4 0.0 42 4.7 0.0 4.2 3 0 0 3 3 3 0 PPR repeat ANAPC3 PF12895.7 CBZ34087.1 - 0.059 13.6 0.1 0.16 12.2 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CBZ34087.1 - 0.45 11.3 6.9 0.85 10.4 4.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Kinesin PF00225.23 CBZ34088.1 - 4.9e-85 285.4 0.0 7e-46 156.7 0.0 2.5 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ34088.1 - 8.5e-20 71.2 0.0 2.4e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding CCDC144C PF14915.6 CBZ34088.1 - 0.12 11.4 41.7 0.061 12.4 6.9 3.6 3 1 1 4 4 4 0 CCDC144C protein coiled-coil region KASH_CCD PF14662.6 CBZ34088.1 - 0.55 10.0 32.0 1.1 9.0 16.6 3.9 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 CBZ34088.1 - 1.1 9.4 19.8 5.9 7.1 2.6 5.1 3 2 1 4 4 4 0 bZIP transcription factor HALZ PF02183.18 CBZ34088.1 - 1.2 9.4 12.1 6.6 7.0 0.1 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper Fzo_mitofusin PF04799.13 CBZ34088.1 - 3 7.4 9.8 0.88 9.1 0.5 3.4 2 1 0 2 2 2 0 fzo-like conserved region Pox_A_type_inc PF04508.12 CBZ34088.1 - 3.1 7.8 9.1 1 9.3 0.3 3.4 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF5082 PF16888.5 CBZ34088.1 - 5 7.4 22.2 0.42 10.9 3.7 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF5082) AAA PF00004.29 CBZ34089.1 - 1.7e-43 148.2 0.1 4e-43 147.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ34089.1 - 8.3e-11 41.5 0.0 1.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CBZ34089.1 - 4.3e-06 26.8 0.1 4.3e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ34089.1 - 1.3e-05 25.5 0.1 0.0054 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ34089.1 - 1.9e-05 25.1 0.2 0.00082 19.8 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 CBZ34089.1 - 1.9e-05 24.8 0.0 4.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 CBZ34089.1 - 0.00016 20.9 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBZ34089.1 - 0.00025 20.8 0.0 0.00066 19.4 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CBZ34089.1 - 0.0021 18.3 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBZ34089.1 - 0.0052 16.3 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 CBZ34089.1 - 0.0053 16.7 0.0 0.35 10.8 0.0 2.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 CBZ34089.1 - 0.0061 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBZ34089.1 - 0.0077 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBZ34089.1 - 0.0086 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 CBZ34089.1 - 0.0087 15.5 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CBZ34089.1 - 0.01 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CBZ34089.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CBZ34089.1 - 0.012 16.1 0.1 0.036 14.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 CBZ34089.1 - 0.012 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CBZ34089.1 - 0.015 15.1 0.2 0.057 13.1 0.1 2.0 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CBZ34089.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.26 CBZ34089.1 - 0.054 13.2 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CBZ34089.1 - 0.08 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 CBZ34089.1 - 0.094 12.0 0.0 0.25 10.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 CBZ34089.1 - 0.13 11.7 0.2 0.29 10.6 0.1 1.6 1 1 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 CBZ34089.1 - 0.14 12.5 0.1 0.46 10.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBZ34089.1 - 0.14 11.7 0.0 0.4 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CBZ34089.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CBZ34089.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rer1 PF03248.13 CBZ34090.1 - 2e-52 177.4 5.3 2.3e-52 177.2 5.3 1.0 1 0 0 1 1 1 1 Rer1 family DUF2244 PF10003.9 CBZ34090.1 - 9.8 5.8 10.5 7 6.3 0.3 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) TrmO PF01980.16 CBZ34091.1 - 9.8e-30 103.2 0.0 1.8e-24 86.2 0.0 2.4 2 0 0 2 2 2 2 tRNA-methyltransferase O PWWP PF00855.17 CBZ34091.1 - 0.00012 22.4 0.1 0.00049 20.5 0.0 2.1 2 0 0 2 2 2 1 PWWP domain Acetyltransf_3 PF13302.7 CBZ34092.1 - 5.4e-12 46.6 0.1 8.7e-07 29.7 0.0 2.9 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ34092.1 - 2e-05 24.8 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 CBZ34092.1 - 0.00023 20.8 0.8 0.013 15.2 0.1 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBZ34092.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 CBZ34092.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UQ_con PF00179.26 CBZ34093.1 - 5.6e-42 142.7 0.0 7.2e-42 142.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBZ34093.1 - 7.3e-05 22.5 0.0 9.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF4984 PF16372.5 CBZ34093.1 - 0.19 11.6 0.1 1.2 9.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4984) AAA PF00004.29 CBZ34094.1 - 5.3e-38 130.4 0.0 1.7e-37 128.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CBZ34094.1 - 3.1e-16 59.1 0.7 8.1e-16 57.7 0.7 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CBZ34094.1 - 2.4e-12 46.5 0.2 7e-12 45.0 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBZ34094.1 - 2.5e-05 24.7 2.8 0.0032 17.9 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CBZ34094.1 - 3e-05 24.0 0.1 0.00031 20.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBZ34094.1 - 0.0004 20.5 0.1 0.004 17.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CBZ34094.1 - 0.00043 20.1 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CBZ34094.1 - 0.0017 17.6 0.3 0.0041 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CBZ34094.1 - 0.0019 18.5 4.1 0.25 11.6 0.1 3.1 2 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CBZ34094.1 - 0.0078 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CBZ34094.1 - 0.0089 16.2 2.0 0.036 14.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CBZ34094.1 - 0.022 14.5 0.0 0.065 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CBZ34094.1 - 0.053 12.9 0.1 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.6 CBZ34094.1 - 0.059 12.9 1.2 0.21 11.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CBZ34094.1 - 0.062 13.0 0.4 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 CBZ34094.1 - 0.062 12.7 0.1 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 CBZ34094.1 - 0.074 12.3 1.2 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 CBZ34094.1 - 0.075 12.7 0.0 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 CBZ34094.1 - 0.093 13.3 0.8 0.33 11.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 CBZ34094.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CBZ34094.1 - 0.15 12.0 0.2 0.63 9.9 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Menin PF05053.13 CBZ34095.1 - 4.4 5.5 6.4 1.6 7.0 1.1 2.3 1 1 1 2 2 2 0 Menin Armet PF10208.9 CBZ34097.1 - 0.02 14.8 0.0 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding HeH PF12949.7 CBZ34097.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain Torus PF16131.5 CBZ34098.1 - 0.1 13.3 0.6 0.24 12.1 0.3 1.7 1 1 0 1 1 1 0 Torus domain Prefoldin PF02996.17 CBZ34099.1 - 6.9e-19 67.9 2.4 7.9e-19 67.7 1.3 1.6 1 1 1 2 2 2 1 Prefoldin subunit THF_DHG_CYH_C PF02882.19 CBZ34099.1 - 0.038 13.3 0.3 0.075 12.4 0.1 1.5 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1454 PF07305.12 CBZ34100.1 - 0.0067 15.9 0.0 0.0069 15.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1454) zf-CCCH PF00642.24 CBZ34102.1 - 0.0005 19.9 0.9 0.0005 19.9 0.9 3.5 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ34102.1 - 0.0007 19.6 12.2 0.05 13.7 3.9 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CBZ34102.1 - 0.025 14.4 9.5 0.076 12.8 2.0 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger SBE2 PF17076.5 CBZ34102.1 - 8.7 4.4 10.1 23 3.0 10.1 1.6 1 0 0 1 1 1 0 SBE2, cell-wall formation NAD_binding_1 PF00175.21 CBZ34104.1 - 7.5e-26 90.9 0.0 1.1e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBZ34104.1 - 6.3e-25 87.4 0.0 9.8e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBZ34104.1 - 0.00017 21.7 0.0 0.00033 20.8 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CBZ34105.1 - 1.3e-26 93.4 0.0 1.8e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBZ34105.1 - 7e-21 74.4 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBZ34105.1 - 1.2e-06 28.8 0.0 6.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SUI1 PF01253.22 CBZ34106.1 - 1.1e-16 61.1 0.0 5.2e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CBZ34106.1 - 0.0002 22.0 0.5 0.00083 20.0 0.1 2.2 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 CBZ34106.1 - 0.022 14.7 0.1 0.075 13.0 0.1 2.0 1 0 0 1 1 1 0 PUA domain SWIB PF02201.18 CBZ34106.1 - 0.15 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 SWIB/MDM2 domain Pkinase PF00069.25 CBZ34108.1 - 1.6e-63 214.5 0.0 2e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34108.1 - 1.9e-32 112.6 0.0 2.5e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ34108.1 - 7.8e-05 22.1 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBZ34108.1 - 0.032 13.6 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBZ34108.1 - 0.041 12.7 0.2 0.082 11.7 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 CBZ34108.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family MMR_HSR1 PF01926.23 CBZ34109.1 - 1.3e-16 60.6 0.0 4.9e-16 58.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBZ34109.1 - 1.7e-07 31.4 0.0 1.6e-05 25.0 0.1 2.4 1 1 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 CBZ34109.1 - 0.00015 21.4 0.0 0.001 18.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ34109.1 - 0.0008 19.4 0.0 0.019 14.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 CBZ34109.1 - 0.011 15.3 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 CBZ34109.1 - 0.012 14.9 0.0 0.027 13.8 0.0 1.5 2 0 0 2 2 2 0 Septin AIG1 PF04548.16 CBZ34109.1 - 0.12 11.6 0.0 0.44 9.8 0.0 1.9 1 1 0 1 1 1 0 AIG1 family FeoB_N PF02421.18 CBZ34109.1 - 0.2 11.2 0.0 0.53 9.8 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B YbaB_DNA_bd PF02575.16 CBZ34110.1 - 0.00015 21.9 0.0 0.00029 21.0 0.0 1.4 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family HIF-1 PF11413.8 CBZ34110.1 - 0.019 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 Ribosomal_L22 PF00237.19 CBZ34113.1 - 1e-12 48.2 0.0 1.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e IQ PF00612.27 CBZ34116.1 - 0.75 9.8 4.8 2 8.4 4.8 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif Prp18 PF02840.15 CBZ34117.1 - 3.2e-11 43.4 0.1 8.5e-11 42.1 0.1 1.6 1 0 0 1 1 1 1 Prp18 domain EF-hand_6 PF13405.6 CBZ34118.1 - 7.8e-13 47.2 0.5 0.017 15.0 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 CBZ34118.1 - 1.4e-08 35.0 1.8 0.0069 16.8 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 CBZ34118.1 - 1.5e-07 30.4 0.0 0.49 10.1 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CBZ34118.1 - 0.0063 16.3 0.2 1.1 9.2 0.0 3.4 4 0 0 4 4 4 1 EF-hand domain pair HupE_UreJ PF04955.12 CBZ34119.1 - 0.01 15.3 0.7 0.015 14.7 0.7 1.2 1 0 0 1 1 1 0 HupE / UreJ protein Pkinase PF00069.25 CBZ34120.1 - 9.4e-62 208.7 0.0 1.1e-61 208.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34120.1 - 2.2e-42 145.1 0.0 2.7e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ34120.1 - 2.9e-09 36.7 0.0 4.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ34120.1 - 0.00042 19.2 0.0 0.00064 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ34120.1 - 0.041 13.2 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ34120.1 - 0.065 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ34120.1 - 0.21 10.5 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinesin PF00225.23 CBZ34121.1 - 4.4e-88 295.4 0.1 4.4e-88 295.4 0.1 2.2 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ34121.1 - 1.6e-12 47.6 0.3 2e-06 27.8 0.2 3.2 2 0 0 2 2 2 2 Microtubule binding KELK PF15796.5 CBZ34121.1 - 0.0031 17.9 2.4 0.0031 17.9 2.4 9.5 8 2 0 9 9 9 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Shugoshin_N PF07558.11 CBZ34121.1 - 0.64 9.9 5.3 25 4.8 0.1 4.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Macoilin PF09726.9 CBZ34122.1 - 8.5 4.8 9.0 16 3.9 9.0 1.4 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 CBZ34123.1 - 0.0027 18.5 0.0 0.09 13.7 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat FlgD_ig PF13860.6 CBZ34124.1 - 0.099 12.5 0.0 9.2 6.2 0.0 3.0 2 0 0 2 2 2 0 FlgD Ig-like domain UAA PF08449.11 CBZ34126.1 - 7e-31 107.6 10.7 2.6e-30 105.7 10.6 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 CBZ34126.1 - 0.64 10.2 22.5 0.18 12.0 4.7 4.0 4 0 0 4 4 4 0 EamA-like transporter family Extensin_2 PF04554.13 CBZ34127.1 - 0.0027 17.7 6.6 0.0037 17.3 6.6 1.2 1 0 0 1 1 1 1 Extensin-like region Calcipressin PF04847.12 CBZ34127.1 - 0.5 10.1 2.7 0.57 9.9 2.7 1.2 1 0 0 1 1 1 0 Calcipressin DUF2457 PF10446.9 CBZ34127.1 - 1.2 8.2 5.1 1.4 8.0 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kelch_5 PF13854.6 CBZ34128.1 - 6e-21 74.0 8.2 1.4e-06 28.2 0.2 7.1 6 1 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 CBZ34128.1 - 1.7e-16 60.0 13.7 0.0058 16.6 0.1 7.1 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CBZ34128.1 - 2.8e-16 59.1 4.3 0.007 16.6 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 CBZ34128.1 - 2.8e-14 52.9 27.1 0.00067 19.9 0.1 8.2 8 1 0 8 8 8 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ34128.1 - 3.6e-12 45.7 12.0 0.00091 18.8 0.4 7.3 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.15 CBZ34128.1 - 1.1e-05 25.1 13.3 0.003 17.5 0.3 5.8 6 1 0 6 6 6 2 Kelch motif BTB PF00651.31 CBZ34128.1 - 3e-05 24.2 0.5 0.0045 17.2 0.0 3.6 4 0 0 4 4 4 1 BTB/POZ domain CheY-binding PF09078.11 CBZ34128.1 - 0.0068 16.5 0.1 0.48 10.6 0.0 2.5 2 0 0 2 2 2 1 CheY binding TSP9 PF11493.8 CBZ34128.1 - 0.1 13.3 0.2 0.98 10.1 0.2 2.8 1 0 0 1 1 1 0 Thylakoid soluble phosphoprotein TSP9 Ldt_C PF17969.1 CBZ34129.1 - 0.28 11.9 1.6 0.5 11.1 0.3 2.1 2 0 0 2 2 2 0 L,D-transpeptidase C-terminal domain MFS_1 PF07690.16 CBZ34130.1 - 3.2e-23 82.2 25.9 3.2e-23 82.2 25.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CBZ34130.1 - 5.9e-17 61.2 15.0 4.2e-11 41.8 2.3 3.8 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CBZ34130.1 - 3.7e-15 55.8 2.4 3.7e-15 55.8 2.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CBZ34130.1 - 8.8e-08 31.8 3.6 8.8e-08 31.8 3.6 2.6 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB LSM PF01423.22 CBZ34131.1 - 8.3e-13 47.8 0.1 1e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SP2 PF03014.14 CBZ34131.1 - 0.0038 15.7 0.1 0.0041 15.6 0.1 1.0 1 0 0 1 1 1 1 Structural protein 2 SM-ATX PF14438.6 CBZ34131.1 - 0.041 14.0 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Med20 PF08612.11 CBZ34131.1 - 0.078 12.3 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF3924 PF13062.6 CBZ34131.1 - 0.098 12.6 0.3 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) SPX PF03105.19 CBZ34132.1 - 0.16 11.9 0.3 0.25 11.2 0.2 1.4 1 1 0 1 1 1 0 SPX domain CRAL_TRIO PF00650.20 CBZ34134.1 - 2.5e-13 50.1 0.0 8.9e-13 48.3 0.0 1.8 1 1 0 1 1 1 1 CRAL/TRIO domain zf-C3HC4_3 PF13920.6 CBZ34135.1 - 4.8e-09 35.9 10.6 8.3e-09 35.2 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ34135.1 - 0.087 12.7 9.8 0.19 11.6 9.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBZ34135.1 - 0.13 12.2 10.0 0.24 11.4 10.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain AAA_6 PF12774.7 CBZ34136.1 - 2e-129 431.3 0.1 3.1e-126 420.8 0.0 4.1 3 1 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ34136.1 - 5.4e-87 292.5 0.7 3.2e-86 289.9 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CBZ34136.1 - 6.8e-63 211.7 0.0 2.3e-60 203.4 0.0 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 CBZ34136.1 - 2.3e-58 197.6 0.0 1.1e-36 126.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CBZ34136.1 - 1.3e-44 151.9 0.0 7.3e-38 129.9 0.0 4.6 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 CBZ34136.1 - 1.6e-36 126.0 2.5 2.7e-36 125.3 2.5 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CBZ34136.1 - 2.7e-30 105.2 0.0 5.6e-11 42.6 0.0 6.2 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 CBZ34136.1 - 7.6e-23 80.9 0.0 3.8e-22 78.6 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_C PF18199.1 CBZ34136.1 - 8.5e-23 81.0 0.0 1.9e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 CBZ34136.1 - 2.7e-21 76.1 0.0 6e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CBZ34136.1 - 1.6e-19 70.6 0.3 3.7e-06 27.4 0.0 5.3 5 0 0 5 5 4 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ34136.1 - 1.8e-14 54.2 6.2 1.3e-05 25.5 0.0 6.8 7 0 0 7 7 5 3 AAA domain AAA_16 PF13191.6 CBZ34136.1 - 3.5e-13 50.3 5.6 0.017 15.5 0.0 7.6 5 0 0 5 5 4 4 AAA ATPase domain AAA_18 PF13238.6 CBZ34136.1 - 4e-07 30.6 0.0 2.9 8.5 0.0 5.2 4 0 0 4 4 4 1 AAA domain AAA_24 PF13479.6 CBZ34136.1 - 7.4e-07 29.1 0.1 2 8.1 0.0 4.4 4 0 0 4 4 4 2 AAA domain FtsK_SpoIIIE PF01580.18 CBZ34136.1 - 2e-06 27.4 0.1 0.032 13.6 0.0 3.9 3 0 0 3 3 3 2 FtsK/SpoIIIE family IstB_IS21 PF01695.17 CBZ34136.1 - 4e-06 26.7 1.4 0.015 15.0 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein T2SSE PF00437.20 CBZ34136.1 - 5.1e-06 25.8 0.0 0.55 9.2 0.0 4.2 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_30 PF13604.6 CBZ34136.1 - 3.7e-05 23.5 4.8 0.67 9.7 0.1 4.4 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 CBZ34136.1 - 5.5e-05 23.4 7.9 0.42 10.8 0.0 5.1 5 0 0 5 5 4 2 AAA domain AAA_25 PF13481.6 CBZ34136.1 - 0.00026 20.6 2.9 0.099 12.2 0.0 4.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CBZ34136.1 - 0.00027 21.3 0.2 4.5 7.7 0.0 4.5 4 0 0 4 4 4 0 RNA helicase Sigma54_activat PF00158.26 CBZ34136.1 - 0.00044 20.0 0.0 0.44 10.2 0.0 3.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_19 PF13245.6 CBZ34136.1 - 0.00049 20.5 6.2 1.5 9.1 0.0 5.0 5 0 0 5 5 4 1 AAA domain AAA_lid_1 PF17857.1 CBZ34136.1 - 0.001 19.3 0.0 0.0037 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain Mg_chelatase PF01078.21 CBZ34136.1 - 0.0013 18.1 5.3 0.24 10.7 0.0 3.8 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 CBZ34136.1 - 0.0015 18.2 1.6 1.8 8.4 0.0 4.2 4 0 0 4 4 3 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBZ34136.1 - 0.0017 18.3 0.0 14 5.5 0.0 4.0 3 0 0 3 3 3 0 RsgA GTPase RuvB_N PF05496.12 CBZ34136.1 - 0.0039 16.9 0.4 1.3 8.7 0.0 3.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Dynein_AAA_lid PF17852.1 CBZ34136.1 - 0.0043 17.1 0.1 0.018 15.1 0.1 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Rad17 PF03215.15 CBZ34136.1 - 0.0044 17.0 0.1 5.1 7.0 0.0 4.1 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_28 PF13521.6 CBZ34136.1 - 0.0098 16.1 0.9 31 4.8 0.0 5.0 4 0 0 4 4 4 0 AAA domain TrwB_AAD_bind PF10412.9 CBZ34136.1 - 0.069 12.1 1.4 3 6.7 0.2 3.1 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain POT1PC PF16686.5 CBZ34136.1 - 0.18 11.7 0.0 0.58 10.0 0.0 1.9 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein SRP54 PF00448.22 CBZ34136.1 - 0.21 11.2 2.6 10 5.7 0.1 3.9 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 CBZ34136.1 - 0.33 10.1 2.6 1.4 8.0 0.0 3.1 4 0 0 4 4 4 0 NB-ARC domain AAA_11 PF13086.6 CBZ34136.1 - 0.41 10.4 14.5 1.6 8.4 0.0 5.0 5 0 0 5 5 5 0 AAA domain ABC_tran PF00005.27 CBZ34136.1 - 0.44 11.1 10.4 1.6 9.2 0.0 4.5 5 0 0 5 5 3 0 ABC transporter DUF87 PF01935.17 CBZ34136.1 - 0.7 9.9 2.4 28 4.7 0.0 3.6 4 0 0 4 4 3 0 Helicase HerA, central domain MAD PF05557.13 CBZ34136.1 - 1.1 7.6 18.3 0.0043 15.5 1.1 3.1 3 0 0 3 3 3 0 Mitotic checkpoint protein PhoH PF02562.16 CBZ34136.1 - 1.4 8.3 7.5 0.65 9.4 0.0 3.3 4 0 0 4 4 3 0 PhoH-like protein Filament PF00038.21 CBZ34136.1 - 4.8 6.7 19.4 6.3 6.3 4.6 3.2 2 0 0 2 2 2 0 Intermediate filament protein HemX PF04375.14 CBZ34136.1 - 5.2 6.3 19.6 3.4 6.9 1.8 2.8 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4201 PF13870.6 CBZ34136.1 - 5.3 6.7 14.1 0.036 13.8 2.6 2.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4201) Sec34 PF04136.15 CBZ34136.1 - 5.7 6.8 9.5 0.37 10.7 1.6 3.0 2 0 0 2 2 2 0 Sec34-like family DUF4407 PF14362.6 CBZ34136.1 - 8.7 5.6 17.5 2.1 7.7 2.7 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Lactamase_B_2 PF12706.7 CBZ34137.1 - 1.2e-14 54.3 0.1 4.4e-11 42.7 0.1 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBZ34137.1 - 5.2e-05 23.3 0.6 0.00011 22.3 0.6 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF3330 PF11809.8 CBZ34137.1 - 0.13 12.3 0.1 0.33 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Adap_comp_sub PF00928.21 CBZ34138.1 - 9.2e-84 280.9 0.4 1.1e-83 280.7 0.4 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family PhetRS_B1 PF18262.1 CBZ34138.1 - 0.044 14.0 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain Pkinase PF00069.25 CBZ34139.1 - 1.3e-13 50.9 0.0 2.8e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34139.1 - 0.0018 17.6 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CBZ34139.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CBZ34141.1 - 2.6e-22 79.5 0.0 4.6e-19 68.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34141.1 - 1.1e-07 31.4 0.0 2.7e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ34141.1 - 0.13 11.5 0.0 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like ChaC PF04752.12 CBZ34143.1 - 5.5e-44 150.3 0.0 5.2e-43 147.2 0.0 1.9 1 1 0 1 1 1 1 ChaC-like protein ChaC PF04752.12 CBZ34144.1 - 5.5e-44 150.3 0.0 5.2e-43 147.2 0.0 1.9 1 1 0 1 1 1 1 ChaC-like protein WD40 PF00400.32 CBZ34145.1 - 2.6e-08 34.4 0.5 0.00033 21.4 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ34145.1 - 0.038 14.3 0.0 5.9 7.3 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SHS2_Rpb7-N PF03876.17 CBZ34147.1 - 0.00029 21.2 0.0 0.022 15.1 0.0 2.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 PSRP-3_Ycf65 PF04839.13 CBZ34147.1 - 0.18 12.0 2.0 0.8 10.0 0.0 2.8 3 0 0 3 3 3 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) GTP_EFTU PF00009.27 CBZ34148.1 - 9.4e-33 113.4 3.8 3.9e-31 108.1 3.8 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ34148.1 - 5e-10 39.5 0.2 9.7e-10 38.5 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ34148.1 - 1.6e-05 24.5 0.1 3.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 CBZ34148.1 - 0.00033 20.2 0.0 0.00066 19.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit IF-2 PF11987.8 CBZ34148.1 - 0.00046 20.3 0.0 0.0015 18.6 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 PduV-EutP PF10662.9 CBZ34148.1 - 0.0014 18.3 0.1 0.005 16.6 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CBZ34148.1 - 0.0081 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CBZ34148.1 - 0.019 15.0 1.2 1.9 8.6 0.1 2.9 2 1 1 3 3 3 0 Dynamin family WD40 PF00400.32 CBZ34149.1 - 1.7e-12 47.6 18.1 0.00081 20.2 0.4 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ34149.1 - 0.0012 19.1 0.0 1.4 9.3 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain MORN PF02493.20 CBZ34151.1 - 8.7e-07 28.5 13.5 0.045 13.7 1.3 3.5 3 0 0 3 3 3 3 MORN repeat Ribonuc_red_sm PF00268.21 CBZ34153.1 - 1.7e-23 83.5 0.0 2.3e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Atg8 PF02991.16 CBZ34154.1 - 7.5e-12 45.4 0.0 2.9e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CBZ34154.1 - 0.00066 20.0 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Csm1_N PF18504.1 CBZ34155.1 - 0.11 12.8 3.6 0.54 10.6 0.5 2.8 2 0 0 2 2 2 0 Csm1 N-terminal domain PipA PF07108.11 CBZ34156.1 - 0.11 12.0 0.4 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 PipA protein ING PF12998.7 CBZ34156.1 - 0.12 12.9 1.8 0.13 12.9 0.4 1.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Swi5 PF07061.11 CBZ34156.1 - 0.19 11.8 3.3 0.5 10.5 0.9 2.3 2 0 0 2 2 2 0 Swi5 Nmad5 PF18757.1 CBZ34156.1 - 0.39 10.9 3.0 0.99 9.6 0.3 2.1 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 DUF2508 PF10704.9 CBZ34156.1 - 0.43 10.8 3.3 1 9.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Mto2_bdg PF12808.7 CBZ34156.1 - 0.69 10.3 13.8 0.086 13.2 1.6 3.3 2 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TMF_TATA_bd PF12325.8 CBZ34156.1 - 1.9 8.7 12.0 1.6 9.0 4.0 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding KELK PF15796.5 CBZ34156.1 - 2 8.9 10.7 12 6.4 1.2 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF349 PF03993.12 CBZ34156.1 - 2.7 8.3 7.2 7.1 7.0 1.3 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF2203 PF09969.9 CBZ34156.1 - 2.8 8.7 5.3 2.1 9.1 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4407 PF14362.6 CBZ34156.1 - 7.6 5.8 9.2 29 3.9 9.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4164 PF13747.6 CBZ34156.1 - 8.8 6.7 16.0 3.5 8.0 2.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) FapA PF03961.13 CBZ34157.1 - 0.26 9.9 3.6 17 3.9 0.0 3.3 3 0 0 3 3 3 0 Flagellar Assembly Protein A IFT57 PF10498.9 CBZ34157.1 - 0.29 10.1 13.8 0.12 11.3 3.5 3.4 4 0 0 4 4 4 0 Intra-flagellar transport protein 57 Spc7 PF08317.11 CBZ34157.1 - 0.29 10.0 28.7 0.064 12.1 12.7 4.0 4 0 0 4 4 4 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 CBZ34157.1 - 2.4 7.5 38.1 0.017 14.6 8.7 4.2 5 0 0 5 5 5 0 Golgin subfamily A member 5 Filament PF00038.21 CBZ34158.1 - 0.011 15.4 8.2 0.011 15.4 8.2 5.3 4 1 1 5 5 5 0 Intermediate filament protein COMP PF11598.8 CBZ34158.1 - 0.018 15.5 0.2 0.018 15.5 0.2 4.7 5 0 0 5 5 5 0 Cartilage oligomeric matrix protein DivIC PF04977.15 CBZ34159.1 - 0.016 15.0 0.4 0.016 15.0 0.4 2.8 2 1 1 3 3 3 0 Septum formation initiator PKcGMP_CC PF16808.5 CBZ34159.1 - 0.041 13.7 0.6 0.041 13.7 0.6 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fib_alpha PF08702.10 CBZ34159.1 - 0.084 13.1 1.4 13 6.0 1.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 CBZ34159.1 - 0.089 12.8 4.7 0.14 12.1 0.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF812 PF05667.11 CBZ34159.1 - 0.45 9.3 14.6 0.13 11.1 9.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Spc7 PF08317.11 CBZ34159.1 - 2.2 7.1 12.3 4.3 6.1 0.3 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF641 PF04859.12 CBZ34159.1 - 4.1 7.7 11.8 4.8 7.5 0.1 3.7 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) DUF16 PF01519.16 CBZ34159.1 - 4.4 7.8 5.7 24 5.5 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 GAS PF13851.6 CBZ34159.1 - 6.9 6.0 16.8 4.5 6.6 12.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Methyltransf_28 PF02636.17 CBZ34160.1 - 3.9e-37 128.3 0.0 5.6e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 CBZ34160.1 - 0.0022 17.1 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CBZ34160.1 - 0.0038 17.9 0.0 0.012 16.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ34160.1 - 0.014 16.1 0.0 0.027 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ34160.1 - 0.038 13.8 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DHHC PF01529.20 CBZ34161.1 - 1e-30 106.5 8.5 1e-30 106.5 8.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase polyprenyl_synt PF00348.17 CBZ34162.1 - 1.1e-73 247.5 0.5 1.4e-73 247.1 0.5 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ribosomal_L28e PF01778.17 CBZ34164.1 - 1.8e-28 99.6 0.3 3.6e-28 98.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CBZ34164.1 - 2.2e-15 57.1 24.5 7.4e-15 55.4 24.1 2.1 1 1 1 2 2 2 1 Mak16 protein C-terminal region Gag_p24 PF00607.20 CBZ34164.1 - 0.06 13.2 0.1 0.16 11.8 0.1 1.6 1 1 1 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) CDC45 PF02724.14 CBZ34164.1 - 1.4 7.1 14.1 0.77 8.0 12.5 1.3 1 1 0 1 1 1 0 CDC45-like protein YqfQ PF14181.6 CBZ34164.1 - 3.8 7.7 9.4 1.4 9.1 4.7 2.0 2 0 0 2 2 2 0 YqfQ-like protein MORN PF02493.20 CBZ34166.1 - 5.4e-46 151.8 81.8 8.7e-05 22.2 0.9 12.9 13 0 0 13 13 13 12 MORN repeat EF-hand_1 PF00036.32 CBZ34167.1 - 4.3e-27 91.6 8.2 2.8e-08 32.7 0.4 4.5 4 1 1 5 5 5 4 EF hand EF-hand_7 PF13499.6 CBZ34167.1 - 4.4e-25 87.9 1.3 2e-11 44.2 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ34167.1 - 1.7e-20 71.2 4.6 6e-07 28.9 0.1 4.7 3 1 2 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CBZ34167.1 - 8e-19 67.2 7.5 6.7e-10 38.7 0.3 3.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CBZ34167.1 - 6e-17 60.3 9.9 1.7e-05 24.1 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CBZ34167.1 - 1.4e-07 31.8 0.1 1.6e-06 28.3 0.0 2.1 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CBZ34167.1 - 4.3e-07 29.8 2.8 0.048 13.6 0.8 3.3 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand Ribosomal_L11 PF00298.19 CBZ34167.1 - 0.024 15.1 0.0 3.2 8.3 0.0 2.3 1 1 1 2 2 2 0 Ribosomal protein L11, RNA binding domain EFhand_Ca_insen PF08726.10 CBZ34167.1 - 0.043 13.9 0.2 9.6 6.4 0.0 2.7 2 1 0 2 2 2 0 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.9 CBZ34167.1 - 0.066 13.5 0.1 0.2 12.0 0.0 1.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3911 PF13050.6 CBZ34167.1 - 0.081 13.0 0.1 0.19 11.9 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3911) MIP PF00230.20 CBZ34168.1 - 4.3e-24 85.5 14.2 2.2e-23 83.2 14.2 1.8 1 1 0 1 1 1 1 Major intrinsic protein DUF3792 PF12670.7 CBZ34168.1 - 9.7 6.4 15.5 3.4 7.9 2.0 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF3792) FKBP_C PF00254.28 CBZ34169.1 - 5.5e-30 103.5 0.0 6.4e-30 103.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-RanBP PF00641.18 CBZ34170.1 - 3.5 7.0 7.9 13 5.2 7.9 1.9 1 1 0 1 1 1 0 Zn-finger in Ran binding protein and others Pro_isomerase PF00160.21 CBZ34171.1 - 1.1e-35 123.2 0.0 1.5e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EF-hand_8 PF13833.6 CBZ34172.1 - 3.9e-10 39.4 1.3 5.1e-10 39.1 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 CBZ34172.1 - 0.0014 19.0 0.7 0.0057 17.1 0.7 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ34172.1 - 0.0053 16.2 0.6 0.022 14.3 0.1 2.2 2 0 0 2 2 2 1 EF hand DUF4604 PF15377.6 CBZ34172.1 - 0.006 17.0 4.5 0.0081 16.6 4.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) EF-hand_6 PF13405.6 CBZ34172.1 - 0.018 15.0 0.2 0.1 12.6 0.2 2.3 2 0 0 2 2 2 0 EF-hand domain MAM33 PF02330.16 CBZ34174.1 - 2.9e-19 69.9 0.1 1.9e-17 63.9 0.1 2.2 1 1 0 1 1 1 1 Mitochondrial glycoprotein Metallophos PF00149.28 CBZ34175.1 - 3.2e-11 44.1 0.0 4.5e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 CBZ34175.1 - 0.045 12.1 0.1 1.6 6.9 0.0 2.7 3 0 0 3 3 3 0 Firmicute fructose-1,6-bisphosphatase CATSPERB PF15149.6 CBZ34175.1 - 0.061 11.9 0.0 0.084 11.4 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family DUF4440 PF14534.6 CBZ34175.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) HA2 PF04408.23 CBZ34176.1 - 5.7e-18 65.2 0.0 1.5e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ34176.1 - 1.2e-14 54.6 0.0 2.4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ34176.1 - 3.3e-08 33.5 0.0 1.1e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ34176.1 - 2e-05 24.9 0.0 5.4e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBZ34176.1 - 0.008 16.5 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ribosom_S12_S23 PF00164.25 CBZ34176.1 - 0.014 15.0 0.0 0.14 11.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S12/S23 R3H PF01424.22 CBZ34176.1 - 0.038 14.0 0.0 0.095 12.7 0.0 1.8 1 0 0 1 1 1 0 R3H domain AAA_25 PF13481.6 CBZ34176.1 - 0.052 13.1 0.0 3.4 7.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 CBZ34176.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 CBZ34176.1 - 0.15 12.6 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L14e PF01929.17 CBZ34178.1 - 3.8e-17 62.5 2.2 3.8e-17 62.5 2.2 2.6 3 1 0 3 3 3 1 Ribosomal protein L14 KOW PF00467.29 CBZ34178.1 - 0.00024 20.9 0.9 0.0004 20.2 0.9 1.4 1 0 0 1 1 1 1 KOW motif CoaE PF01121.20 CBZ34179.1 - 1.3e-42 145.5 0.0 2.4e-42 144.6 0.0 1.4 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CBZ34179.1 - 0.00019 21.9 0.3 0.0068 17.0 0.2 2.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 CBZ34179.1 - 0.031 14.0 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family SKI PF01202.22 CBZ34179.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate kinase tRNA-synt_2c PF01411.19 CBZ34180.1 - 1.6e-193 644.2 0.0 2.2e-193 643.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CBZ34180.1 - 5.4e-11 42.4 0.0 1.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CBZ34180.1 - 0.00036 21.0 4.9 0.00042 20.8 1.6 2.8 2 1 2 4 4 4 1 DHHA1 domain FliMN_C PF01052.20 CBZ34181.1 - 0.037 14.0 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Type III flagellar switch regulator (C-ring) FliN C-term RNase_PH PF01138.21 CBZ34184.1 - 4.6e-09 36.9 0.0 1e-08 35.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBZ34184.1 - 2.7e-05 24.1 0.1 5.3e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NAD_binding_5 PF07994.12 CBZ34184.1 - 0.026 13.9 0.1 0.041 13.3 0.1 1.2 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase TEX13 PF15186.6 CBZ34184.1 - 0.081 12.6 1.8 0.21 11.3 1.8 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Apo-CIII PF05778.12 CBZ34184.1 - 0.12 12.0 0.6 0.31 10.7 0.6 1.6 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) Metallophos PF00149.28 CBZ34186.1 - 1.7e-10 41.8 0.0 3.2e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBZ34186.1 - 1.1e-05 25.7 0.0 2.1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ASH PF15780.5 CBZ34188.1 - 1.6e-38 130.9 24.8 2.4e-07 30.9 0.0 16.3 16 0 0 16 16 16 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CBZ34188.1 - 2.9e-10 40.3 0.1 0.26 11.6 0.1 7.9 9 0 0 9 9 9 2 Transmembrane protein 131-like Motile_Sperm PF00635.26 CBZ34188.1 - 2.7e-08 33.6 0.0 5.5 6.9 0.0 8.8 11 0 0 11 11 11 2 MSP (Major sperm protein) domain PapD-like PF14874.6 CBZ34188.1 - 4.4e-05 23.6 13.1 0.015 15.4 0.0 7.6 6 1 1 7 7 7 1 Flagellar-associated PapD-like MYCBPAP PF14646.6 CBZ34188.1 - 0.0018 17.3 0.0 0.48 9.3 0.0 4.1 5 0 0 5 5 5 1 MYCBP-associated protein family CAF1 PF04857.20 CBZ34189.1 - 1.7e-22 80.0 3.0 1.6e-11 44.0 0.1 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease cobW PF02492.19 CBZ34191.1 - 8.9e-28 97.1 0.1 1.3e-27 96.5 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CBZ34191.1 - 0.003 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain TrwB_AAD_bind PF10412.9 CBZ34191.1 - 0.0056 15.6 0.0 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 CBZ34191.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 CBZ34191.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 CBZ34191.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CBZ34191.1 - 0.052 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CBZ34191.1 - 0.079 13.3 0.0 0.26 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CBZ34191.1 - 0.094 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 CBZ34191.1 - 0.14 11.9 0.0 0.57 9.9 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RINT1_TIP1 PF04437.13 CBZ34192.1 - 0.0029 16.5 0.5 0.0052 15.7 0.0 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family PI-PLC-X PF00388.19 CBZ34194.1 - 4.9e-60 201.3 0.0 1e-59 200.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBZ34194.1 - 1.1e-31 109.5 0.0 3.8e-31 107.8 0.0 2.0 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CBZ34194.1 - 1.6e-09 38.0 0.0 3.2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 CBZ34194.1 - 7.7e-08 32.7 0.2 2.8e-07 30.9 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ34194.1 - 0.00016 21.0 0.1 0.00064 19.1 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBZ34194.1 - 0.0028 17.5 0.0 0.044 13.7 0.0 2.8 2 1 0 2 2 2 1 EF-hand domain AAA PF00004.29 CBZ34195.1 - 0.0003 21.2 0.0 0.0022 18.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Asparaginase_C PF17763.1 CBZ34197.1 - 0.12 12.6 0.2 0.24 11.6 0.2 1.5 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain DUF1216 PF06746.11 CBZ34198.1 - 0.043 13.8 0.5 0.089 12.8 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1216) UTP15_C PF09384.10 CBZ34200.1 - 6.2e-30 103.8 0.7 9.4e-30 103.2 0.7 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CBZ34200.1 - 1.4e-12 47.9 4.5 0.012 16.4 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat AhpC-TSA PF00578.21 CBZ34201.1 - 4.1e-38 130.1 0.0 5.3e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ34201.1 - 6e-16 58.5 0.0 7.3e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CBZ34201.1 - 2.2e-08 33.8 0.1 4e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin EIAV_GP90 PF00971.18 CBZ34201.1 - 0.19 10.4 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 EIAV coat protein, gp90 Pro_isomerase PF00160.21 CBZ34202.1 - 2.2e-46 158.0 0.0 3.6e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arginase PF00491.21 CBZ34204.1 - 9.8e-29 100.7 0.0 1.3e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Arginase family Tropomyosin_1 PF12718.7 CBZ34205.1 - 7.4e-06 26.2 5.1 7.4e-06 26.2 5.1 4.4 1 1 3 4 4 4 1 Tropomyosin like ATPase PF06745.13 CBZ34205.1 - 8.9 5.6 13.4 0.48 9.7 7.3 2.1 2 1 0 2 2 2 0 KaiC RMI1_N PF08585.12 CBZ34206.1 - 2.9e-25 89.3 0.3 1.4e-24 87.1 0.3 1.8 1 1 0 1 1 1 1 RecQ mediated genome instability protein Methyltransf_16 PF10294.9 CBZ34207.1 - 6e-16 58.7 0.0 8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 CBZ34207.1 - 1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ34207.1 - 1.1e-08 35.7 0.0 3.7e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ34207.1 - 3.7e-08 34.0 0.1 7.2e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBZ34207.1 - 2e-05 24.2 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 CBZ34207.1 - 0.00018 20.6 0.0 0.00027 20.1 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_11 PF08241.12 CBZ34207.1 - 0.00019 22.0 0.1 0.00047 20.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 CBZ34207.1 - 0.0032 16.9 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 CBZ34207.1 - 0.0056 16.3 0.0 0.0086 15.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 CBZ34207.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 CBZ34207.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MethyltransfD12 PF02086.15 CBZ34207.1 - 0.064 12.9 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase NTP_transferase PF00483.23 CBZ34208.1 - 9.9e-50 169.4 0.0 1.4e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CBZ34208.1 - 8.9e-12 45.6 0.0 1.3e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 CBZ34208.1 - 5.1e-11 41.9 11.6 3.4e-07 29.7 1.6 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 CBZ34208.1 - 8.8e-07 28.2 0.1 0.007 15.3 0.2 2.9 2 1 1 3 3 3 2 L-fucokinase DUF4954 PF16314.5 CBZ34208.1 - 0.0041 15.3 1.2 0.0059 14.8 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 CBZ34208.1 - 0.016 15.0 0.6 0.016 15.0 0.6 3.8 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 CBZ34208.1 - 0.033 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase Beach PF02138.18 CBZ34209.1 - 7.9e-99 330.5 0.0 1.4e-98 329.7 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CBZ34209.1 - 0.0062 16.6 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Pro_isomerase PF00160.21 CBZ34210.1 - 6.1e-14 52.6 0.0 7.5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ATP-synt_C PF00137.21 CBZ34211.1 - 4.9e-27 94.0 36.5 1e-15 57.8 14.7 2.2 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 CBZ34211.1 - 2.5 6.5 9.0 2.8 6.3 0.8 2.1 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF4064 PF13273.6 CBZ34211.1 - 4 7.8 20.5 2.1 8.7 9.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF4064) Abhydrolase_6 PF12697.7 CBZ34212.1 - 1.3e-17 65.2 4.9 2.2e-17 64.4 4.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBZ34212.1 - 1.2e-15 57.9 0.3 2.2e-15 57.0 0.1 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ34212.1 - 2e-11 43.6 0.0 5.1e-11 42.3 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CBZ34212.1 - 8.6e-05 22.5 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 CBZ34212.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase LRR_6 PF13516.6 CBZ34213.1 - 2.3e-11 42.8 10.9 0.0016 18.3 0.0 9.0 11 0 0 11 11 11 5 Leucine Rich repeat cNMP_binding PF00027.29 CBZ34214.1 - 5.7e-07 29.5 0.1 0.055 13.5 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF3040 PF11239.8 CBZ34214.1 - 0.11 12.8 0.5 0.82 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) APG6_N PF17675.1 CBZ34215.1 - 0.0059 17.1 4.0 0.008 16.7 4.0 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region YqjK PF13997.6 CBZ34215.1 - 0.048 13.9 4.7 0.13 12.5 4.7 1.8 1 0 0 1 1 1 0 YqjK-like protein DUF3287 PF11690.8 CBZ34215.1 - 0.048 13.4 5.1 0.084 12.6 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) TMF_DNA_bd PF12329.8 CBZ34215.1 - 0.076 13.0 0.6 0.076 13.0 0.6 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FapA PF03961.13 CBZ34215.1 - 0.083 11.5 0.2 0.1 11.1 0.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A RasGAP_C PF03836.15 CBZ34215.1 - 0.14 12.3 3.5 0.23 11.6 2.7 1.7 2 1 0 2 2 2 0 RasGAP C-terminus DivIC PF04977.15 CBZ34215.1 - 0.35 10.7 7.3 0.083 12.7 2.4 2.2 1 1 1 2 2 2 0 Septum formation initiator HAUS-augmin3 PF14932.6 CBZ34215.1 - 1.1 8.7 8.2 1.6 8.2 8.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF724 PF05266.14 CBZ34215.1 - 3.6 7.4 7.4 8.2 6.2 7.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF4807 PF16065.5 CBZ34216.1 - 0.1 12.3 0.2 0.73 9.5 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4807) YjgF_endoribonc PF14588.6 CBZ34218.1 - 2.8e-32 111.9 0.1 3.1e-32 111.8 0.1 1.0 1 0 0 1 1 1 1 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 CBZ34218.1 - 2.4e-19 69.5 0.0 3.3e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP ABC_membrane PF00664.23 CBZ34219.1 - 6.3e-58 196.6 31.2 1.1e-33 117.1 10.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ34219.1 - 1.3e-21 77.6 0.0 2.3e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter T2SSE PF00437.20 CBZ34219.1 - 0.00016 20.8 0.0 0.00031 19.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.6 CBZ34219.1 - 0.00035 21.0 0.3 0.0013 19.2 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CBZ34219.1 - 0.0004 20.0 0.4 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CBZ34219.1 - 0.0013 18.5 0.0 0.003 17.3 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase SMC_N PF02463.19 CBZ34219.1 - 0.0017 17.8 0.1 0.2 11.1 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ34219.1 - 0.003 17.3 0.2 0.0074 16.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CBZ34219.1 - 0.0036 17.6 0.0 0.0091 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 CBZ34219.1 - 0.0041 16.5 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 CBZ34219.1 - 0.0059 16.5 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CBZ34219.1 - 0.013 15.3 0.0 0.044 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ34219.1 - 0.04 14.4 0.0 0.079 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ34219.1 - 0.051 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 CBZ34219.1 - 0.09 12.4 0.1 0.52 9.9 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 CBZ34219.1 - 0.097 12.8 0.4 0.17 12.0 0.4 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 CBZ34219.1 - 0.1 12.8 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain CAP_GLY PF01302.25 CBZ34220.1 - 0.0081 16.2 0.1 0.028 14.5 0.1 1.8 2 0 0 2 2 2 1 CAP-Gly domain FERM_F1 PF18379.1 CBZ34220.1 - 0.058 13.4 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain Caskin1-CID PF16600.5 CBZ34221.1 - 2.7 8.7 7.0 0.7 10.5 1.0 2.2 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain Yip1 PF04893.17 CBZ34224.1 - 2.3e-16 60.0 18.5 3e-16 59.6 18.3 1.3 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 CBZ34224.1 - 0.33 10.7 11.9 0.57 9.9 11.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) ABC_membrane PF00664.23 CBZ34225.1 - 3.6e-68 230.2 26.2 3.2e-34 118.8 14.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ34225.1 - 2.3e-21 76.7 0.0 4.9e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CBZ34225.1 - 0.0019 17.6 0.0 0.0049 16.2 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family SMC_N PF02463.19 CBZ34225.1 - 0.002 17.6 0.2 1.9 7.9 0.1 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBZ34225.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CBZ34225.1 - 0.0071 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain CAP_GLY PF01302.25 CBZ34225.1 - 0.012 15.6 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 CAP-Gly domain AAA_16 PF13191.6 CBZ34225.1 - 0.029 14.7 0.3 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 CBZ34225.1 - 0.042 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CBZ34225.1 - 0.067 12.2 0.0 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 CBZ34225.1 - 0.1 12.7 0.2 0.54 10.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBZ34225.1 - 0.11 12.7 0.0 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CBZ34225.1 - 0.18 11.5 0.0 0.65 9.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 CBZ34225.1 - 0.21 11.6 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Dynamin family AAA_23 PF13476.6 CBZ34225.1 - 0.27 11.7 0.1 0.48 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain Arginosuc_synth PF00764.19 CBZ34226.1 - 1.5e-148 495.2 0.0 1.8e-148 495.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CBZ34226.1 - 0.086 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC adh_short_C2 PF13561.6 CBZ34227.1 - 1.9e-33 116.0 1.2 1.4e-30 106.6 1.2 2.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBZ34227.1 - 6.2e-25 87.8 0.0 4.8e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 CBZ34227.1 - 0.006 16.1 0.1 0.17 11.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family zf-C3HC4 PF00097.25 CBZ34228.1 - 2.3e-06 27.4 7.4 4.3e-06 26.5 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ34228.1 - 2.2e-05 24.4 7.2 4.8e-05 23.3 7.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ34228.1 - 0.003 17.5 7.3 0.0064 16.4 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CBZ34228.1 - 0.0048 16.7 8.1 0.0094 15.8 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ34228.1 - 0.0069 16.5 8.9 0.016 15.4 8.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING EccE PF11203.8 CBZ34228.1 - 0.025 14.9 3.3 0.14 12.5 0.2 3.1 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE TF_Zn_Ribbon PF08271.12 CBZ34228.1 - 0.1 12.1 5.7 0.27 10.8 5.7 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RING_2 PF13639.6 CBZ34228.1 - 0.42 11.0 8.4 0.91 9.9 8.4 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.6 CBZ34228.1 - 0.44 10.5 6.5 3.7 7.5 6.5 2.4 1 1 0 1 1 1 0 zf-RING of BARD1-type protein RNA_POL_M_15KD PF02150.16 CBZ34228.1 - 1.2 9.1 3.9 2.9 7.8 3.9 1.7 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit zf-C3HC4_3 PF13920.6 CBZ34228.1 - 2.2 8.2 8.4 4.9 7.1 8.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ34228.1 - 5.4 7.0 6.9 17 5.4 6.8 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Hus1 PF04005.12 CBZ34229.1 - 3e-90 302.3 0.0 3.4e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein tRNA-synt_1b PF00579.25 CBZ34230.1 - 3.4e-16 59.4 0.0 1e-15 57.9 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) AAA_16 PF13191.6 CBZ34231.1 - 0.0011 19.4 0.3 0.0044 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 CBZ34231.1 - 0.0048 17.4 0.0 0.011 16.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.14 CBZ34231.1 - 0.0074 16.3 0.0 0.026 14.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBZ34231.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBZ34231.1 - 0.02 15.4 0.0 0.064 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBZ34231.1 - 0.031 14.4 0.0 0.087 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.11 CBZ34231.1 - 0.033 14.3 0.0 0.57 10.2 0.0 2.2 1 1 0 1 1 1 0 tRNA ligase kinase domain AAA PF00004.29 CBZ34231.1 - 0.053 13.9 0.0 0.12 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ34231.1 - 0.057 13.7 0.0 0.16 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CBZ34231.1 - 0.062 12.7 0.0 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CBZ34231.1 - 0.069 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_15 PF13175.6 CBZ34231.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 CBZ34231.1 - 0.24 11.3 0.0 0.54 10.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain V-ATPase_G PF03179.15 CBZ34234.1 - 6.3e-22 78.1 13.8 6.9e-22 78.0 13.8 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit PKK PF12474.8 CBZ34234.1 - 0.075 13.2 10.5 0.85 9.7 0.5 2.1 1 1 1 2 2 2 0 Polo kinase kinase FAM193_C PF15914.5 CBZ34234.1 - 0.091 12.5 1.5 0.57 10.0 0.0 2.6 2 1 1 3 3 3 0 FAM193 family C-terminal ALS2CR8 PF15299.6 CBZ34235.1 - 0.032 14.1 0.4 0.052 13.4 0.4 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 ADH_N PF08240.12 CBZ34237.1 - 3.6e-28 97.6 5.8 3.6e-28 97.6 5.8 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBZ34237.1 - 2.6e-22 79.2 0.0 5.3e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CBZ34237.1 - 1e-07 31.5 0.2 1.6e-07 30.9 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CBZ34237.1 - 3.8e-06 26.4 0.2 6.7e-06 25.6 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glu_dehyd_C PF16912.5 CBZ34237.1 - 3.1e-05 23.6 0.2 4.9e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CBZ34237.1 - 4.1e-05 24.6 0.0 9.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 CBZ34237.1 - 0.00012 22.3 0.8 0.00023 21.3 0.8 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 CBZ34237.1 - 0.0014 18.6 0.4 0.0023 17.9 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CBZ34237.1 - 0.0041 17.2 0.5 0.0076 16.3 0.1 1.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 CBZ34237.1 - 0.023 14.1 0.1 0.34 10.3 0.4 2.3 2 1 0 2 2 2 0 short chain dehydrogenase ApbA PF02558.16 CBZ34237.1 - 0.027 14.1 0.2 0.054 13.1 0.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 CBZ34237.1 - 0.047 13.9 0.1 0.082 13.2 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain DUF364 PF04016.12 CBZ34237.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation ABC_tran PF00005.27 CBZ34239.1 - 5.8e-30 104.6 0.0 1.1e-29 103.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CBZ34239.1 - 1.8e-25 89.6 18.3 1.8e-25 89.6 18.3 3.5 4 0 0 4 4 4 1 ABC-2 type transporter AAA_21 PF13304.6 CBZ34239.1 - 0.0005 20.0 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CBZ34239.1 - 0.00063 20.2 0.2 0.0016 18.9 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ34239.1 - 0.001 19.0 0.1 0.0023 17.8 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CBZ34239.1 - 0.0011 18.7 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 CBZ34239.1 - 0.0025 17.0 18.3 0.005 16.0 16.9 2.1 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.6 CBZ34239.1 - 0.0068 16.9 0.3 0.013 16.0 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ34239.1 - 0.012 15.8 0.0 0.03 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBZ34239.1 - 0.024 15.2 0.1 0.048 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBZ34239.1 - 0.053 13.2 0.1 0.099 12.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CBZ34239.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 CBZ34239.1 - 0.21 11.8 0.7 0.42 10.8 0.7 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CBZ34239.1 - 0.22 11.1 1.3 0.39 10.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain C1_1 PF00130.22 CBZ34239.1 - 0.29 11.1 5.3 0.78 9.7 5.3 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CAP_N PF01213.19 CBZ34242.1 - 0.27 10.7 0.3 0.3 10.5 0.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aldose_epim PF01263.20 CBZ34243.1 - 1.4e-55 188.7 0.0 2.6e-54 184.6 0.0 2.0 1 1 0 1 1 1 1 Aldose 1-epimerase FtsX PF02687.21 CBZ34245.1 - 4.3e-16 59.2 20.8 1.7e-10 41.2 9.4 6.9 7 1 0 7 7 7 3 FtsX-like permease family CHAP PF05257.16 CBZ34246.1 - 1.5e-09 38.3 1.4 2.9e-08 34.2 1.4 2.5 1 1 0 1 1 1 1 CHAP domain DUF3558 PF12079.8 CBZ34246.1 - 0.013 15.5 0.3 0.033 14.2 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) DUF1664 PF07889.12 CBZ34248.1 - 0.01 15.9 3.7 0.01 15.9 3.7 11.9 8 4 7 15 15 15 0 Protein of unknown function (DUF1664) HWE_HK PF07536.14 CBZ34248.1 - 0.75 10.5 0.0 0.75 10.5 0.0 9.7 8 2 3 12 12 12 0 HWE histidine kinase AMPKBI PF04739.15 CBZ34249.1 - 1.6e-14 53.9 1.5 3.9e-14 52.7 1.5 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CBZ34249.1 - 2.8e-08 33.8 0.0 5.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase PTP_tm PF18861.1 CBZ34250.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SET PF00856.28 CBZ34252.1 - 8.6e-14 52.3 0.0 3e-13 50.5 0.0 1.8 1 1 0 1 1 1 1 SET domain FtsJ PF01728.19 CBZ34253.1 - 2.7e-46 157.9 0.0 3.2e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CBZ34253.1 - 0.051 13.4 0.0 0.069 13.0 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 CBZ34254.1 - 4.2e-86 289.2 0.2 5.1e-86 288.9 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CBZ34254.1 - 1.2e-18 66.7 3.2 2.8e-18 65.6 3.2 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CBZ34254.1 - 7.5e-18 65.3 0.6 1.6e-17 64.3 0.6 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EF-hand_6 PF13405.6 CBZ34255.1 - 1.2e-07 31.1 0.0 0.0082 16.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CBZ34255.1 - 4.3e-05 23.9 0.0 7.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ34255.1 - 9.5e-05 21.7 0.0 0.0048 16.4 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CBZ34255.1 - 0.0038 17.1 0.3 0.32 10.9 0.1 2.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CBZ34255.1 - 0.0082 15.6 0.1 0.84 9.2 0.0 2.5 2 0 0 2 2 2 1 EF hand XRN_N PF03159.18 CBZ34256.1 - 1.1e-59 201.8 0.0 1.7e-59 201.2 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CBZ34256.1 - 9e-10 38.1 2.2 0.00014 21.0 0.0 3.3 3 0 0 3 3 3 3 Xrn1 helical domain GIT_CC PF16559.5 CBZ34257.1 - 0.15 12.0 0.3 24 4.9 0.2 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor SKA2 PF16740.5 CBZ34257.1 - 0.25 11.1 4.9 0.43 10.4 1.8 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 YlqD PF11068.8 CBZ34257.1 - 0.26 11.7 1.8 3.9 7.9 0.1 2.4 2 0 0 2 2 2 0 YlqD protein Prefoldin PF02996.17 CBZ34257.1 - 0.79 9.6 4.5 1.6 8.7 0.4 2.7 2 1 0 2 2 2 0 Prefoldin subunit GFO_IDH_MocA PF01408.22 CBZ34258.1 - 5.9e-12 46.5 0.5 5.4e-11 43.4 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 CBZ34258.1 - 0.012 16.2 0.1 0.061 13.9 0.1 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CDT1_C PF16679.5 CBZ34258.1 - 0.012 16.0 0.4 0.057 13.9 0.0 2.2 2 1 1 3 3 3 0 DNA replication factor Cdt1 C-terminal domain Rossmann-like PF10727.9 CBZ34258.1 - 0.02 14.8 0.4 0.28 11.1 0.1 2.6 1 1 1 2 2 2 0 Rossmann-like domain GFO_IDH_MocA PF01408.22 CBZ34259.1 - 1.8e-13 51.4 0.2 2.8e-13 50.7 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 CBZ34259.1 - 0.15 12.5 0.3 0.28 11.6 0.3 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CAF1 PF04857.20 CBZ34262.1 - 3.2e-70 236.8 0.0 4.2e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease CALM_bind PF16025.5 CBZ34262.1 - 0.022 15.2 0.3 0.042 14.3 0.3 1.5 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding LprI PF07007.12 CBZ34262.1 - 1.2 9.8 5.9 35 5.1 0.0 2.5 2 0 0 2 2 2 0 Lysozyme inhibitor LprI Kelch_3 PF13415.6 CBZ34263.1 - 9.8e-12 44.9 10.1 4e-07 30.2 0.3 5.9 4 2 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ34263.1 - 1.1e-11 44.4 9.0 0.0041 17.1 0.1 4.8 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 CBZ34263.1 - 5.9e-10 39.0 11.4 0.00092 19.2 0.0 6.2 5 2 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ34263.1 - 8e-10 38.1 3.0 0.0021 17.6 0.1 4.5 4 1 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CBZ34263.1 - 2.3e-08 34.0 2.6 0.52 10.7 0.1 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CBZ34263.1 - 1.2e-06 28.2 0.2 1.4 9.0 0.0 5.2 4 0 0 4 4 4 2 Kelch motif tRNA_bind PF01588.20 CBZ34264.1 - 5.2e-13 48.9 0.5 7.4e-13 48.4 0.5 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain zf-RanBP PF00641.18 CBZ34264.1 - 0.001 18.4 1.3 0.0021 17.4 1.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.6 CBZ34264.1 - 0.078 12.7 4.3 0.18 11.6 4.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Cu2_monoox_C PF03712.15 CBZ34264.1 - 0.2 11.1 1.2 0.28 10.7 1.2 1.3 1 1 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Lactamase_B PF00753.27 CBZ34265.1 - 2.1e-08 34.4 0.5 1.6e-06 28.2 0.2 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily PAP2 PF01569.21 CBZ34266.1 - 1.4e-08 34.6 6.7 1.3e-07 31.5 4.3 2.7 2 1 0 2 2 2 1 PAP2 superfamily ThiF PF00899.21 CBZ34267.1 - 4.3e-85 285.0 2.9 1e-63 215.0 0.0 2.6 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CBZ34267.1 - 3.9e-67 226.8 0.9 5.8e-67 226.2 0.9 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CBZ34267.1 - 1.4e-12 48.1 0.0 2.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 CBZ34267.1 - 0.0002 21.5 0.1 0.00064 19.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CBZ34267.1 - 0.00025 21.2 0.0 0.00074 19.7 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 CBZ34267.1 - 0.0048 17.0 0.2 2.2 8.4 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Kinesin PF00225.23 CBZ34268.1 - 1.9e-87 293.3 0.1 4.7e-87 292.0 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ34268.1 - 4.6e-15 55.9 0.1 1.7e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding MYCBPAP PF14646.6 CBZ34269.1 - 4.9e-11 42.2 3.7 3.4e-09 36.1 0.1 3.0 2 1 0 2 2 2 2 MYCBP-associated protein family TMEM192 PF14802.6 CBZ34272.1 - 0.086 11.9 1.2 0.13 11.3 1.2 1.2 1 0 0 1 1 1 0 TMEM192 family BING4CT PF08149.11 CBZ34274.1 - 2e-29 101.2 0.2 1.7e-28 98.2 0.0 2.5 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.32 CBZ34274.1 - 2.4e-06 28.1 3.4 1.6e-05 25.5 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat ABC1 PF03109.16 CBZ34274.1 - 0.07 13.3 0.1 0.23 11.6 0.1 1.9 1 0 0 1 1 1 0 ABC1 family Sec10 PF07393.11 CBZ34275.1 - 8.8e-31 107.1 0.6 9.9e-26 90.4 0.0 3.1 2 1 0 3 3 3 3 Exocyst complex component Sec10 Spc7 PF08317.11 CBZ34275.1 - 0.8 8.5 4.9 2 7.2 4.9 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein Presenilin PF01080.17 CBZ34276.1 - 0.038 12.7 14.0 0.1 11.4 14.0 1.8 1 0 0 1 1 1 0 Presenilin SID-1_RNA_chan PF13965.6 CBZ34276.1 - 0.14 10.6 2.4 0.29 9.5 2.4 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PA26 PF04636.13 CBZ34276.1 - 0.37 9.6 10.1 0.66 8.8 10.1 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TFIIA PF03153.13 CBZ34276.1 - 0.44 10.5 17.1 0.58 10.1 17.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM60A PF15396.6 CBZ34276.1 - 0.52 10.3 6.3 1 9.3 6.3 1.6 1 0 0 1 1 1 0 Protein Family FAM60A LAP1C PF05609.12 CBZ34276.1 - 0.54 9.3 15.5 0.81 8.7 15.5 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF2946 PF11162.8 CBZ34276.1 - 0.93 10.2 9.3 8.4 7.1 3.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) DUF4778 PF16008.5 CBZ34276.1 - 1.2 9.1 14.0 1.8 8.6 14.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) U79_P34 PF03064.16 CBZ34276.1 - 2.7 7.3 18.2 4.4 6.6 18.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SLC12 PF03522.15 CBZ34276.1 - 3.2 6.7 10.4 4.3 6.3 10.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PorA PF11271.8 CBZ34276.1 - 4.3 6.6 10.5 0.031 13.6 2.1 1.8 2 0 0 2 2 2 0 Porin PorA DUF572 PF04502.13 CBZ34276.1 - 6.9 6.2 24.5 10 5.7 24.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SprA-related PF12118.8 CBZ34276.1 - 8.1 5.5 27.7 14 4.7 27.7 1.3 1 0 0 1 1 1 0 SprA-related family DIM1 PF02966.16 CBZ34277.1 - 2.9e-31 108.0 0.1 5e-27 94.3 0.1 2.1 2 0 0 2 2 2 2 Mitosis protein DIM1 DUF1205 PF06722.12 CBZ34278.1 - 0.13 12.3 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) GFO_IDH_MocA PF01408.22 CBZ34279.1 - 7.2e-11 43.0 0.0 1.4e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Pyrid_ox_like PF16242.5 CBZ34279.1 - 0.06 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like PriCT_2 PF08707.11 CBZ34280.1 - 4e-17 62.3 2.6 4e-17 62.3 2.6 1.8 2 0 0 2 2 2 1 Primase C terminal 2 (PriCT-2) PPL5 PF18168.1 CBZ34280.1 - 1.7e-07 30.8 8.3 0.00011 21.6 0.0 3.2 3 0 0 3 3 3 2 Prim-pol family 5 DNA_primase_S PF01896.19 CBZ34280.1 - 0.0093 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 DNA primase small subunit Macoilin PF09726.9 CBZ34280.1 - 0.79 8.2 5.8 1.2 7.6 5.8 1.2 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CBZ34280.1 - 1 9.3 16.8 1.9 8.4 16.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 CBZ34280.1 - 1.1 8.3 6.4 1.7 7.8 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Thiolase_N PF00108.23 CBZ34281.1 - 1.4e-13 50.8 5.9 3.2e-13 49.7 3.4 2.5 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CBZ34281.1 - 8.2e-13 48.1 0.1 3.8e-11 42.7 0.1 2.5 1 1 1 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CBZ34281.1 - 1.2e-07 31.6 0.9 2.2e-07 30.7 0.4 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CBZ34281.1 - 0.026 14.4 1.6 2.1 8.2 1.1 2.8 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 CBZ34281.1 - 0.32 11.0 3.8 1.9 8.5 0.2 3.3 3 1 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain COX17 PF05051.13 CBZ34282.1 - 6.1e-06 26.5 0.3 9.1e-06 25.9 0.3 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) ACAS_N PF16177.5 CBZ34283.1 - 9.1e-20 70.3 3.2 1.6e-19 69.5 3.2 1.4 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus RRM_1 PF00076.22 CBZ34284.1 - 9.7e-12 44.5 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBZ34285.1 - 1.9e-13 50.0 0.0 3.5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.23 CBZ34286.1 - 1.7e-10 41.0 0.0 3.9e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CBZ34286.1 - 1.8e-05 24.9 0.1 0.00013 22.0 0.1 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CBZ34286.1 - 0.00027 20.9 0.0 0.0065 16.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CBZ34286.1 - 0.017 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CBZ34286.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.27 CBZ34286.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF1738 PF08401.11 CBZ34288.1 - 0.00036 20.6 1.0 0.27 11.3 0.3 3.1 2 1 1 3 3 3 2 Domain of unknown function (DUF1738) DUF2121 PF09894.9 CBZ34288.1 - 0.066 12.8 0.0 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) DUF676 PF05057.14 CBZ34290.1 - 9.6e-13 48.1 0.0 2.3e-10 40.4 0.0 2.6 2 1 0 2 2 2 2 Putative serine esterase (DUF676) DUF1638 PF07796.11 CBZ34290.1 - 0.093 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) SET PF00856.28 CBZ34291.1 - 8.9e-13 49.0 0.0 3.1e-10 40.7 0.0 2.9 3 0 0 3 3 3 2 SET domain zf-Mss51 PF13824.6 CBZ34291.1 - 0.0052 16.9 1.0 0.014 15.5 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 CBZ34291.1 - 0.02 15.0 2.3 0.02 15.0 2.3 3.1 5 0 0 5 5 5 0 MYND finger FAD-oxidase_C PF02913.19 CBZ34293.1 - 6.1e-47 160.3 0.0 9.2e-47 159.8 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBZ34293.1 - 2.4e-30 105.1 1.9 2.9e-30 104.8 0.5 1.8 2 1 0 2 2 2 1 FAD binding domain SET PF00856.28 CBZ34294.1 - 4.7e-10 40.1 0.0 1.2e-09 38.8 0.0 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 CBZ34294.1 - 1.5 8.9 15.0 0.1 12.7 8.3 2.5 2 1 0 2 2 2 0 MYND finger Na_H_Exchanger PF00999.21 CBZ34295.1 - 2.1e-48 165.0 42.9 3.1e-48 164.5 42.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Mucin PF01456.17 CBZ34296.1 - 4.5 7.3 12.2 0.25 11.3 4.4 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Shisa PF13908.6 CBZ34297.1 - 0.026 14.7 0.3 0.061 13.6 0.3 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Prominin PF05478.11 CBZ34297.1 - 0.063 11.2 1.3 0.09 10.7 1.3 1.1 1 0 0 1 1 1 0 Prominin DUF3481 PF11980.8 CBZ34297.1 - 0.37 10.5 1.8 0.93 9.2 1.8 1.6 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein TPR_12 PF13424.6 CBZ34299.1 - 0.001 19.3 10.0 0.78 10.1 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Plant_NMP1 PF06694.11 CBZ34299.1 - 0.042 13.0 0.3 0.091 11.9 0.3 1.5 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) TPR_17 PF13431.6 CBZ34299.1 - 0.069 13.6 0.2 0.43 11.1 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4919 PF16266.5 CBZ34299.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) TPR_14 PF13428.6 CBZ34299.1 - 0.43 11.5 7.5 1.3 10.1 0.1 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat ADH_zinc_N_2 PF13602.6 CBZ34300.1 - 5.4e-17 63.1 0.0 1.5e-16 61.6 0.0 1.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ34300.1 - 6e-08 32.5 0.2 2.7e-07 30.4 0.1 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBZ34300.1 - 6.8e-08 32.6 0.0 9.1e-07 28.9 0.0 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ABC1 PF03109.16 CBZ34300.1 - 0.06 13.5 0.3 0.14 12.3 0.3 1.6 1 0 0 1 1 1 0 ABC1 family RBM1CTR PF08081.11 CBZ34300.1 - 0.19 11.8 0.4 0.4 10.8 0.4 1.4 1 0 0 1 1 1 0 RBM1CTR (NUC064) family Glyco_hydro_32N PF00251.20 CBZ34301.1 - 1.3e-45 156.3 1.3 1.5e-45 156.1 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Methyltransf_28 PF02636.17 CBZ34302.1 - 2.3e-60 204.5 0.0 3.1e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NIF PF03031.18 CBZ34303.1 - 0.0045 16.8 0.1 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Peptidase_M17 PF00883.21 CBZ34306.1 - 6.3e-102 341.0 0.0 8.6e-102 340.6 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain CHB_HEX_C_1 PF13290.6 CBZ34307.1 - 1.7e-06 28.0 0.1 0.00031 20.7 0.1 2.6 2 0 0 2 2 2 2 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 CBZ34307.1 - 6.2e-05 23.1 0.0 0.14 12.3 0.0 3.6 4 0 0 4 4 4 2 Fn3 associated DUF3576 PF12100.8 CBZ34311.1 - 0.01 16.0 0.1 0.84 9.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3576) DUF4298 PF14131.6 CBZ34311.1 - 0.034 14.1 1.0 0.1 12.5 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) OmpH PF03938.14 CBZ34311.1 - 0.065 13.6 6.8 0.048 14.0 4.7 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fez1 PF06818.15 CBZ34311.1 - 0.087 13.3 7.1 0.064 13.7 5.4 1.6 2 0 0 2 2 2 0 Fez1 APG6_N PF17675.1 CBZ34311.1 - 0.14 12.6 5.8 0.37 11.3 2.2 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 CBZ34311.1 - 1.7 8.8 7.0 2.7 8.2 5.4 2.1 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 CBZ34311.1 - 2.8 7.1 6.4 1.2 8.4 3.9 1.6 2 0 0 2 2 2 0 TMPIT-like protein DUF1168 PF06658.12 CBZ34311.1 - 2.8 7.7 11.9 2.2 8.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) KIAA1430 PF13879.6 CBZ34315.1 - 0.058 14.2 4.6 0.19 12.5 1.7 2.0 1 1 1 2 2 2 0 KIAA1430 homologue 5-FTHF_cyc-lig PF01812.20 CBZ34317.1 - 2.7e-13 50.2 3.6 1.1e-09 38.4 0.1 3.9 3 1 0 3 3 3 3 5-formyltetrahydrofolate cyclo-ligase family HIT PF01230.23 CBZ34318.1 - 1e-11 45.4 0.0 2.7e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CBZ34318.1 - 1.8e-06 28.4 0.1 1.2e-05 25.7 0.1 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding LRR_4 PF12799.7 CBZ34321.1 - 2.5e-15 56.3 16.0 0.014 15.8 0.0 7.6 4 3 5 9 9 9 7 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 CBZ34321.1 - 0.0024 17.8 2.8 0.46 10.4 0.0 3.4 2 1 1 3 3 3 1 BspA type Leucine rich repeat region (6 copies) F-box PF00646.33 CBZ34321.1 - 0.039 13.8 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.33 CBZ34321.1 - 0.49 11.1 13.6 53 4.9 0.0 7.1 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 CBZ34321.1 - 3.3 8.0 21.1 8.9 6.7 0.0 8.0 9 0 0 9 9 9 0 Leucine Rich repeat Stealth_CR2 PF11380.8 CBZ34322.1 - 2.4e-24 85.6 0.2 4.6e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 Stealth protein CR2, conserved region 2 DUF2270 PF10028.9 CBZ34322.1 - 0.072 12.7 1.2 0.12 12.0 1.2 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2270) Stealth_CR2 PF11380.8 CBZ34324.1 - 3.3e-19 69.1 0.0 6.6e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 CH PF00307.31 CBZ34325.1 - 0.0026 17.9 0.0 0.0053 16.9 0.0 1.6 1 1 0 1 1 1 1 Calponin homology (CH) domain DHR10 PF18595.1 CBZ34326.1 - 0.0013 18.8 7.6 0.0013 18.8 7.6 5.1 5 1 0 5 5 5 1 Designed helical repeat protein 10 domain Cnn_1N PF07989.11 CBZ34326.1 - 0.003 17.7 0.4 0.003 17.7 0.4 4.5 4 1 0 4 4 4 1 Centrosomin N-terminal motif 1 APG6_N PF17675.1 CBZ34326.1 - 0.0058 17.2 6.6 0.0058 17.2 6.6 5.3 5 1 0 5 5 5 2 Apg6 coiled-coil region DUF3450 PF11932.8 CBZ34326.1 - 0.06 12.6 30.2 0.062 12.6 3.0 4.7 4 1 1 5 5 5 0 Protein of unknown function (DUF3450) Pox_A_type_inc PF04508.12 CBZ34326.1 - 0.27 11.1 8.0 15 5.6 3.5 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DivIC PF04977.15 CBZ34326.1 - 1 9.2 28.7 0.052 13.3 1.0 5.5 5 1 0 5 5 5 0 Septum formation initiator Bacillus_HBL PF05791.11 CBZ34326.1 - 1.6 8.5 3.8 1.1 9.1 0.9 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2681 PF10883.8 CBZ34326.1 - 2.8 8.4 6.2 6.1 7.3 1.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Pox_A_type_inc PF04508.12 CBZ34327.1 - 0.068 13.0 0.4 0.068 13.0 0.4 4.7 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Fez1 PF06818.15 CBZ34327.1 - 9.7 6.6 59.0 0.091 13.2 19.1 4.3 1 1 3 4 4 4 0 Fez1 CdiI_2 PF18593.1 CBZ34328.1 - 0.069 13.8 1.0 1.6 9.5 0.0 3.3 3 1 0 3 3 3 0 CdiI immunity protein BRCA-2_OB3 PF09104.10 CBZ34328.1 - 0.083 12.5 2.3 2 8.1 0.1 3.1 3 0 0 3 3 3 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 SKA2 PF16740.5 CBZ34328.1 - 0.2 11.4 15.0 0.54 10.1 0.5 3.9 5 0 0 5 5 5 0 Spindle and kinetochore-associated protein 2 Serine_rich PF08824.10 CBZ34328.1 - 0.95 9.4 9.8 0.096 12.7 3.1 2.7 3 0 0 3 3 3 0 Serine rich protein interaction domain UPF0242 PF06785.11 CBZ34328.1 - 3.1 7.9 13.3 25 4.9 8.4 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus PAXNEB PF05625.11 CBZ34329.1 - 0.17 11.0 0.8 0.19 10.8 0.8 1.1 1 0 0 1 1 1 0 PAXNEB protein DUF1899 PF08953.11 CBZ34330.1 - 3.8e-11 42.7 0.1 6.3e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CBZ34330.1 - 3.4e-10 39.6 0.0 7.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CBZ34330.1 - 5.1e-06 27.1 7.8 0.024 15.5 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ34330.1 - 0.00037 20.7 0.1 0.0096 16.2 0.1 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ34330.1 - 0.012 14.3 0.1 0.019 13.7 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 ATG16 PF08614.11 CBZ34330.1 - 0.21 11.8 3.9 0.29 11.3 3.9 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Ribosomal_S9 PF00380.19 CBZ34331.1 - 0.00023 21.7 0.0 0.00049 20.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S9/S16 TMEM234 PF10639.9 CBZ34332.1 - 1.1e-37 128.5 2.0 1.3e-37 128.3 2.0 1.0 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 CBZ34332.1 - 1.1e-07 32.1 7.6 3e-05 24.2 2.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family His_Phos_2 PF00328.22 CBZ34333.1 - 3.9e-10 39.7 1.0 2.3e-07 30.5 0.1 2.8 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Methyltransf_5 PF01795.19 CBZ34334.1 - 4e-30 105.4 0.0 5.7e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family Methyltransf_31 PF13847.6 CBZ34334.1 - 3.6e-06 26.8 0.0 0.00029 20.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ34334.1 - 0.00019 22.1 0.0 0.0018 18.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ34334.1 - 0.0095 16.6 0.0 0.35 11.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CBZ34334.1 - 0.17 11.4 0.0 0.51 9.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain ADH_zinc_N PF00107.26 CBZ34334.1 - 0.18 11.8 0.0 23 5.0 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase SIR2 PF02146.17 CBZ34335.1 - 1.4e-35 122.9 0.1 3.5e-34 118.2 0.1 2.1 1 1 0 1 1 1 1 Sir2 family Ribosomal_L32p PF01783.23 CBZ34335.1 - 0.064 13.5 0.4 0.87 9.9 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L32p protein family Cpn60_TCP1 PF00118.24 CBZ34336.1 - 3e-160 534.1 5.2 3.5e-160 533.9 5.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Tipalpha PF16753.5 CBZ34336.1 - 0.066 13.0 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter V_ATPase_I PF01496.19 CBZ34336.1 - 0.21 9.5 0.0 0.27 9.1 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PPR_1 PF12854.7 CBZ34338.1 - 9.4e-06 25.2 0.0 2.2e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.6 CBZ34338.1 - 6.7e-05 22.9 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 CBZ34338.1 - 0.00034 20.7 0.0 0.0013 18.9 0.0 2.0 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 CBZ34338.1 - 0.0045 17.1 0.5 0.014 15.6 0.1 2.1 2 0 0 2 2 2 1 PPR repeat C2-C2_1 PF11618.8 CBZ34339.1 - 7.6e-28 97.4 6.1 2.1e-27 95.9 0.3 3.5 2 1 1 3 3 3 1 First C2 domain of RPGR-interacting protein 1 DUF3153 PF11353.8 CBZ34339.1 - 2.6 7.5 8.6 4.1 6.9 7.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3153) HCMV_UL139 PF12507.8 CBZ34339.1 - 3.5 8.0 11.1 0.27 11.6 0.2 3.4 2 1 1 3 3 3 0 Human Cytomegalovirus UL139 protein RICTOR_M PF14666.6 CBZ34340.1 - 3e-22 78.3 0.0 1.1e-20 73.3 0.0 3.3 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.6 CBZ34340.1 - 4.8e-15 55.4 1.4 2.3e-14 53.2 0.2 2.4 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 CBZ34340.1 - 7.1e-12 45.7 1.7 1.4e-11 44.8 0.3 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 CBZ34340.1 - 0.001 19.3 0.2 0.13 12.5 0.0 4.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 DUF2605 PF10792.9 CBZ34340.1 - 1.1 9.3 3.6 0.79 9.7 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2605) CobD_Cbib PF03186.13 CBZ34342.1 - 0.022 14.0 0.4 0.033 13.4 0.4 1.2 1 0 0 1 1 1 0 CobD/Cbib protein XPG_I PF00867.18 CBZ34343.1 - 9.9e-18 64.3 0.2 4.3e-16 59.0 0.1 2.6 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 CBZ34343.1 - 8.2e-15 55.1 0.1 3.8e-06 27.3 0.0 2.6 3 0 0 3 3 3 2 XPG N-terminal domain XPG_I_2 PF12813.7 CBZ34343.1 - 0.0095 15.4 0.2 0.02 14.4 0.2 1.5 1 0 0 1 1 1 1 XPG domain containing Lentiviral_Tat PF02998.14 CBZ34344.1 - 0.034 14.2 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 Lentiviral Tat protein FA_hydroxylase PF04116.13 CBZ34346.1 - 2.1e-22 79.9 18.6 2.1e-22 79.9 18.6 2.4 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily COX14 PF14880.6 CBZ34346.1 - 0.086 12.7 0.2 0.25 11.2 0.2 1.8 1 0 0 1 1 1 0 Cytochrome oxidase c assembly RSN1_TM PF13967.6 CBZ34346.1 - 0.16 11.7 0.1 0.16 11.7 0.1 2.7 2 1 0 3 3 3 0 Late exocytosis, associated with Golgi transport DHC_N1 PF08385.12 CBZ34347.1 - 4e-149 497.8 0.0 4e-149 497.8 0.0 4.5 5 2 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 CBZ34347.1 - 1.5e-147 490.9 0.0 4.2e-147 489.4 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ34347.1 - 2e-112 376.2 8.8 2e-112 376.2 8.8 4.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ34347.1 - 5.2e-97 324.2 2.2 6.1e-97 324.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ34347.1 - 5.1e-85 285.4 0.8 2.1e-84 283.3 0.0 2.6 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ34347.1 - 5.3e-80 267.7 0.5 5.3e-80 267.7 0.5 3.1 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ34347.1 - 2e-62 209.9 0.4 9.7e-58 194.6 0.0 4.1 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ34347.1 - 2e-52 177.3 0.0 4.6e-52 176.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ34347.1 - 7.4e-44 148.7 0.0 1.9e-42 144.1 0.0 3.4 4 0 0 4 4 4 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBZ34347.1 - 1e-40 139.8 15.1 1e-40 139.8 15.1 1.6 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CBZ34347.1 - 4e-25 88.4 0.3 1.4e-07 31.6 0.0 5.8 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CBZ34347.1 - 8.9e-23 80.8 0.0 3e-22 79.1 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBZ34347.1 - 5.6e-17 61.8 0.1 2.8e-16 59.5 0.1 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBZ34347.1 - 4.7e-06 27.1 5.5 0.52 10.7 0.0 6.1 5 0 0 5 5 4 1 AAA ATPase domain AAA PF00004.29 CBZ34347.1 - 4.9e-06 27.0 0.1 0.45 10.9 0.0 4.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CBZ34347.1 - 0.00037 19.6 4.4 0.3 10.1 0.0 4.3 5 0 0 5 5 5 2 Type II/IV secretion system protein AAA_22 PF13401.6 CBZ34347.1 - 0.0033 17.7 9.1 1.3 9.3 0.0 6.1 6 0 0 6 6 6 1 AAA domain RNA_helicase PF00910.22 CBZ34347.1 - 0.021 15.2 0.1 8 6.9 0.0 3.3 3 0 0 3 3 3 0 RNA helicase Sigma54_activat PF00158.26 CBZ34347.1 - 0.026 14.2 0.0 0.44 10.2 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 CBZ34347.1 - 0.034 14.7 1.1 4.9 7.7 0.0 4.6 5 0 0 5 5 4 0 AAA domain AAA_33 PF13671.6 CBZ34347.1 - 0.067 13.3 0.3 21 5.2 0.0 4.1 3 0 0 3 3 3 0 AAA domain YceI PF04264.13 CBZ34348.1 - 0.00033 21.3 0.0 0.00038 21.0 0.0 1.2 1 0 0 1 1 1 1 YceI-like domain DNA_pol_B PF00136.21 CBZ34349.1 - 8.8e-82 275.2 0.0 1.1e-81 274.9 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBZ34349.1 - 4.5e-07 29.3 0.0 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CBZ34349.1 - 0.0019 18.6 3.1 0.0024 18.3 0.5 2.4 3 0 0 3 3 3 1 C4-type zinc-finger of DNA polymerase delta Radical_SAM_C PF16199.5 CBZ34351.1 - 3.5e-17 62.2 0.2 7.2e-17 61.2 0.2 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CBZ34351.1 - 7.7e-15 55.7 0.0 2.6e-14 53.9 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CBZ34351.1 - 2.7e-07 30.9 0.2 6e-07 29.7 0.2 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBZ34351.1 - 0.00043 20.2 0.2 0.0012 18.8 0.2 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 CBZ34353.1 - 3.8e-35 119.7 0.2 9.1e-16 57.6 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Helicase_C PF00271.31 CBZ34354.1 - 1.2e-11 45.0 0.0 2.6e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ34354.1 - 2.3e-11 43.8 0.0 7.8e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase HHH_5 PF14520.6 CBZ34354.1 - 0.001 19.7 0.0 0.0043 17.6 0.0 2.1 1 0 0 1 1 1 1 Helix-hairpin-helix domain ResIII PF04851.15 CBZ34354.1 - 0.0041 17.1 0.0 0.0076 16.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Hydrolase_4 PF12146.8 CBZ34354.1 - 0.14 11.4 0.5 0.48 9.6 0.2 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 TMEM208_SND2 PF05620.11 CBZ34355.1 - 0.06 13.1 0.5 0.12 12.2 0.5 1.7 1 1 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 MscS_TM PF12794.7 CBZ34355.1 - 3.9 6.2 13.9 0.89 8.4 8.0 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Mog1 PF04603.12 CBZ34356.1 - 5.7e-34 117.5 0.0 7.2e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Fer2_3 PF13085.6 CBZ34358.1 - 1.5e-31 108.6 0.2 5.3e-31 106.8 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 CBZ34358.1 - 0.011 15.6 2.2 0.013 15.4 0.7 1.9 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain TPR_21 PF09976.9 CBZ34358.1 - 0.033 13.9 1.1 0.065 12.9 1.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Acetone_carb_G PF08882.11 CBZ34358.1 - 0.051 13.7 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 Acetone carboxylase gamma subunit TPR_6 PF13174.6 CBZ34358.1 - 0.37 11.5 1.9 0.54 11.0 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ34358.1 - 0.43 11.1 2.6 0.67 10.5 1.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DHHC PF01529.20 CBZ34359.1 - 4.4e-30 104.5 15.7 4.4e-30 104.5 15.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1282 PF06930.12 CBZ34359.1 - 1.5 8.6 14.6 0.047 13.5 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) DHHC PF01529.20 CBZ34360.1 - 2.3e-30 105.4 4.7 2.3e-30 105.4 4.7 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DHHC PF01529.20 CBZ34361.1 - 1.7e-25 89.7 15.1 1.7e-25 89.7 15.1 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase PepSY_TM PF03929.16 CBZ34361.1 - 0.09 12.4 4.5 0.02 14.6 1.1 1.6 2 0 0 2 2 2 0 PepSY-associated TM region PTPlike_phytase PF14566.6 CBZ34362.1 - 1.2e-120 399.0 0.5 3.6e-45 153.9 0.0 3.6 3 0 0 3 3 3 3 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CBZ34362.1 - 0.047 13.6 0.1 3.5 7.5 0.0 3.0 3 0 0 3 3 3 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBZ34362.1 - 0.2 11.2 0.0 35 3.9 0.0 3.0 3 0 0 3 3 3 0 Protein-tyrosine phosphatase ADK PF00406.22 CBZ34363.1 - 2.5e-07 30.9 0.0 0.0015 18.7 0.0 2.3 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CBZ34363.1 - 0.00033 21.1 0.0 0.14 12.5 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 CBZ34363.1 - 0.0005 20.2 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ34363.1 - 0.028 14.7 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ34363.1 - 0.045 14.1 1.9 0.11 12.8 0.9 2.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CBZ34363.1 - 0.05 14.0 0.1 0.32 11.4 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ34363.1 - 0.05 13.6 0.0 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 CBZ34363.1 - 0.13 11.7 0.1 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Rad17 PF03215.15 CBZ34363.1 - 0.42 10.5 1.2 3.8 7.4 0.1 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain B9-C2 PF07162.11 CBZ34365.1 - 1.2e-18 67.9 0.0 1.9e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Mt_ATP-synt_B PF05405.14 CBZ34366.1 - 0.13 11.9 1.3 0.17 11.5 1.3 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Anoctamin PF04547.12 CBZ34367.1 - 0.11 11.3 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Calcium-activated chloride channel Pet100 PF09803.9 CBZ34367.1 - 1.5 9.4 6.5 10 6.7 6.5 2.1 1 1 0 1 1 1 0 Pet100 zf-rbx1 PF12678.7 CBZ34368.1 - 1.2e-12 47.9 5.8 2.5e-12 46.9 5.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CBZ34368.1 - 7.6e-10 39.0 7.5 2.4e-08 34.1 4.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CBZ34368.1 - 5.1e-07 29.4 10.0 8.9e-06 25.4 7.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ34368.1 - 1.1e-06 28.4 6.5 2.2e-06 27.4 6.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ34368.1 - 2.6e-05 24.1 5.5 5.8e-05 23.0 5.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CBZ34368.1 - 0.00031 20.8 5.2 0.0013 18.8 5.2 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CBZ34368.1 - 0.00068 19.6 2.9 0.00068 19.6 2.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CBZ34368.1 - 0.003 17.4 7.8 0.01 15.7 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBZ34368.1 - 0.0033 17.1 7.9 0.0049 16.6 0.9 3.1 3 0 0 3 3 3 1 RING-like zinc finger Prok-RING_4 PF14447.6 CBZ34368.1 - 0.0051 16.6 7.8 0.034 14.0 3.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CBZ34368.1 - 0.05 13.2 4.7 0.074 12.7 2.8 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 CBZ34368.1 - 0.11 12.3 2.7 0.25 11.2 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 CBZ34368.1 - 0.12 12.5 5.6 0.12 12.6 3.2 2.0 2 0 0 2 2 2 0 RING-variant domain GAGA PF09237.11 CBZ34368.1 - 2.6 7.9 5.7 34 4.3 0.7 3.2 3 0 0 3 3 3 0 GAGA factor FANCL_C PF11793.8 CBZ34368.1 - 4 7.7 7.3 27 5.0 7.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain V-SNARE PF05008.15 CBZ34369.1 - 1.4e-07 31.8 0.4 5.9e-05 23.4 0.0 3.3 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 CBZ34369.1 - 6.6e-06 26.0 1.4 1.6e-05 24.7 0.3 2.0 2 0 0 2 2 2 1 Sec20 Laminin_I PF06008.14 CBZ34369.1 - 0.0051 16.5 2.7 0.0051 16.5 2.7 2.0 2 0 0 2 2 2 1 Laminin Domain I V-SNARE_C PF12352.8 CBZ34369.1 - 0.006 16.8 3.4 0.006 16.8 3.4 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus EMP24_GP25L PF01105.24 CBZ34369.1 - 0.036 14.0 0.4 1.6 8.7 0.3 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Fib_alpha PF08702.10 CBZ34369.1 - 0.28 11.4 2.8 10 6.3 1.0 3.0 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Laminin_II PF06009.12 CBZ34369.1 - 0.45 10.5 3.9 6.3 6.8 2.4 2.7 1 1 2 3 3 3 0 Laminin Domain II DUF1640 PF07798.11 CBZ34369.1 - 0.49 10.4 4.8 1.4 9.0 1.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1640) V-SNARE PF05008.15 CBZ34370.1 - 4.5e-13 49.4 0.2 3.4e-12 46.6 0.0 2.6 2 2 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 CBZ34370.1 - 9.9e-07 29.0 0.5 2.6e-06 27.6 0.5 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Unstab_antitox PF09720.10 CBZ34370.1 - 0.00021 21.2 0.6 0.0006 19.8 0.2 2.0 2 0 0 2 2 2 1 Putative addiction module component Sec20 PF03908.13 CBZ34370.1 - 0.00033 20.5 2.0 0.00074 19.4 1.3 1.9 2 0 0 2 2 2 1 Sec20 KASH_CCD PF14662.6 CBZ34370.1 - 0.00043 20.2 4.1 0.062 13.1 0.8 2.2 2 0 0 2 2 2 2 Coiled-coil region of CCDC155 or KASH Baculo_11_kDa PF06143.11 CBZ34370.1 - 0.031 13.8 0.1 0.059 13.0 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Baculo_F PF12259.8 CBZ34370.1 - 0.084 11.4 0.7 0.12 10.9 0.1 1.5 2 0 0 2 2 2 0 Baculovirus F protein XTBD PF11952.8 CBZ34370.1 - 0.086 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD DUF5082 PF16888.5 CBZ34370.1 - 0.23 11.7 4.1 1.1 9.5 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) TRIQK PF15168.6 CBZ34370.1 - 0.24 11.3 1.1 0.36 10.7 0.2 1.8 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family DUF883 PF05957.13 CBZ34370.1 - 0.52 10.9 9.9 0.83 10.3 1.9 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) RTT107_BRCT_5 PF16770.5 CBZ34371.1 - 0.2 11.6 0.0 0.41 10.6 0.0 1.4 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain EXOSC1 PF10447.9 CBZ34372.1 - 0.00026 21.5 0.0 0.032 14.8 0.0 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 TRAM PF01938.20 CBZ34372.1 - 0.011 15.7 0.1 0.033 14.2 0.0 1.9 3 0 0 3 3 3 0 TRAM domain TPH PF13868.6 CBZ34375.1 - 1.5e-35 122.4 127.5 1.5e-35 122.4 127.5 2.1 2 0 0 2 2 2 2 Trichohyalin-plectin-homology domain Semialdhyde_dh PF01118.24 CBZ34375.1 - 2.3 8.7 5.0 4.5 7.7 0.9 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TIP41 PF04176.13 CBZ34376.1 - 4.8e-22 78.3 0.0 7.9e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 TIP41-like family GAF_2 PF13185.6 CBZ34376.1 - 6.5e-12 45.9 0.0 1.2e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CBZ34376.1 - 1e-07 32.7 0.0 2.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 CBZ34376.1 - 0.0009 19.6 0.0 0.0024 18.2 0.0 1.7 2 0 0 2 2 2 1 GAF domain LRR_4 PF12799.7 CBZ34377.1 - 8.1e-06 26.1 4.8 0.001 19.4 0.1 2.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ34377.1 - 0.0018 17.8 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat CDC45 PF02724.14 CBZ34377.1 - 0.08 11.2 6.6 0.1 10.9 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 CBZ34377.1 - 0.47 10.4 7.6 0.71 9.8 7.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.12 CBZ34377.1 - 0.58 9.5 9.6 0.66 9.3 9.6 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 CBZ34377.1 - 1.5 8.7 6.0 2 8.2 6.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 CBZ34377.1 - 5.5 5.1 10.9 6.4 4.9 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family Ala_racemase_N PF01168.20 CBZ34378.1 - 7.8e-22 78.0 0.0 9e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain LRR_8 PF13855.6 CBZ34379.1 - 4.4e-10 39.2 6.4 0.17 11.7 0.1 5.0 4 2 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CBZ34379.1 - 6.1e-09 36.0 8.4 0.049 14.1 0.3 5.8 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ34379.1 - 4.6e-06 26.4 6.1 6.3 7.8 0.0 6.3 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 CBZ34379.1 - 0.00029 20.6 12.6 0.86 9.8 0.4 5.5 6 0 0 6 6 6 3 Leucine Rich repeat PMP1_2 PF08114.11 CBZ34379.1 - 0.009 15.7 0.2 0.017 14.9 0.2 1.4 1 0 0 1 1 1 1 ATPase proteolipid family Coronavirus_5 PF05528.11 CBZ34379.1 - 0.021 14.8 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Coronavirus gene 5 protein STD1 PF17235.2 CBZ34379.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 STD1/MTH1 V_ATPase_I PF01496.19 CBZ34381.1 - 1.5e-261 870.0 21.4 1.9e-238 793.5 12.6 3.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DUF3021 PF11457.8 CBZ34381.1 - 0.017 15.5 5.3 0.017 15.5 5.3 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3021) DegS PF05384.11 CBZ34381.1 - 0.087 12.3 3.7 5.4 6.5 0.0 3.2 3 0 0 3 3 3 0 Sensor protein DegS Atg14 PF10186.9 CBZ34381.1 - 0.57 9.2 2.6 3.2 6.8 2.6 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 CBZ34381.1 - 2.1 8.7 4.4 1.8 9.0 0.1 2.7 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 CBZ34381.1 - 5.7 7.5 5.9 3.3 8.2 0.9 2.5 2 0 0 2 2 2 0 Cell division protein ZapB UbiA PF01040.18 CBZ34382.1 - 8.6e-49 166.1 22.0 1.3e-48 165.5 22.0 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family NRDE-2 PF08424.10 CBZ34385.1 - 1.5e-06 27.6 1.2 0.03 13.4 0.0 4.2 3 1 1 4 4 4 3 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 CBZ34385.1 - 0.00085 19.8 7.2 9.7 6.8 0.0 6.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ34385.1 - 0.035 14.9 26.5 11 7.2 0.0 9.3 7 2 2 9 9 9 0 Tetratricopeptide repeat AsnC_trans_reg2 PF17805.1 CBZ34385.1 - 0.089 13.0 1.9 0.35 11.1 0.1 2.8 3 0 0 3 3 3 0 AsnC-like ligand binding domain Beach PF02138.18 CBZ34387.1 - 1.4e-88 296.9 0.0 1.8e-88 296.5 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain Nuc_deoxyrib_tr PF05014.15 CBZ34388.1 - 1.3e-38 132.0 0.0 1.5e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase DUF4406 PF14359.6 CBZ34388.1 - 0.017 15.5 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4406) BCDHK_Adom3 PF10436.9 CBZ34389.1 - 3.2e-25 88.9 0.0 7.1e-25 87.7 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CBZ34389.1 - 0.078 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ANTH PF07651.16 CBZ34390.1 - 4e-24 85.1 0.2 6.4e-24 84.4 0.2 1.3 1 1 0 1 1 1 1 ANTH domain ENTH PF01417.20 CBZ34390.1 - 0.015 15.4 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 ENTH domain Ribosomal_L22 PF00237.19 CBZ34392.1 - 4.6e-32 110.3 0.4 5.6e-32 110.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF4616 PF15394.6 CBZ34393.1 - 0.016 14.3 0.0 0.03 13.3 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4616) LacI PF00356.21 CBZ34395.1 - 0.11 12.3 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF3592 PF12158.8 CBZ34397.1 - 6.7e-08 32.7 0.3 8.9e-08 32.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) Enkurin PF13864.6 CBZ34398.1 - 4.2e-19 68.8 3.3 6.3e-19 68.2 3.3 1.3 1 0 0 1 1 1 1 Calmodulin-binding PARP_regulatory PF01358.18 CBZ34399.1 - 1.5e-14 53.6 0.0 2.5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Poly A polymerase regulatory subunit UPF0182 PF03699.13 CBZ34399.1 - 0.061 11.5 0.0 0.084 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) WD40 PF00400.32 CBZ34400.1 - 0.021 15.7 9.9 4.9 8.2 0.1 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat Blt1_C PF17183.4 CBZ34400.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Get5 carboxyl domain SsgA PF04686.12 CBZ34400.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA Ank_4 PF13637.6 CBZ34401.1 - 2.1e-39 133.4 4.9 1.6e-08 34.9 0.0 5.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ34401.1 - 6.1e-35 119.7 7.2 3.8e-15 56.2 0.4 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBZ34401.1 - 6.4e-31 106.0 6.0 2.3e-09 37.3 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ34401.1 - 6.1e-27 90.7 3.5 0.00017 21.8 0.1 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 CBZ34401.1 - 3.1e-24 84.3 3.9 0.0001 22.6 0.1 7.3 7 0 0 7 7 7 6 Ankyrin repeat TPR_1 PF00515.28 CBZ34401.1 - 7.3e-09 35.1 1.5 0.044 13.6 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ34401.1 - 1.1e-05 25.1 6.2 0.45 10.8 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ34401.1 - 0.00063 19.4 0.6 0.24 11.1 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_17 PF13431.6 CBZ34401.1 - 0.0013 19.0 1.8 2.8 8.5 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ34401.1 - 0.029 14.6 0.9 0.067 13.4 0.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Clathrin_H_link PF13838.6 CBZ34401.1 - 0.11 12.4 0.5 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Clathrin-H-link PEX11 PF05648.14 CBZ34402.1 - 2e-10 40.5 1.5 4.7e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) PalH PF08733.10 CBZ34402.1 - 0.17 10.8 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 PalH/RIM21 Phosducin PF02114.16 CBZ34404.1 - 1.6e-07 30.6 0.0 2.3e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 Phosducin MRC1 PF09444.10 CBZ34404.1 - 0.00053 20.5 0.8 0.00099 19.6 0.8 1.4 1 0 0 1 1 1 1 MRC1-like domain AAA PF00004.29 CBZ34405.1 - 1e-29 103.6 0.0 2e-26 93.0 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ34405.1 - 2.6e-08 34.2 0.0 0.012 15.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ34405.1 - 6e-08 33.2 6.8 0.00056 20.3 0.1 3.8 2 2 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 CBZ34405.1 - 1.7e-05 24.8 1.5 0.22 11.4 0.6 3.5 2 2 1 3 3 3 2 NACHT domain AAA_5 PF07728.14 CBZ34405.1 - 8.9e-05 22.5 0.2 0.012 15.6 0.0 3.0 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CBZ34405.1 - 0.00012 21.8 0.9 0.41 10.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_tran PF00005.27 CBZ34405.1 - 0.00013 22.5 0.4 0.27 11.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_33 PF13671.6 CBZ34405.1 - 0.00024 21.3 0.1 0.1 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CBZ34405.1 - 0.00026 21.3 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.15 CBZ34405.1 - 0.00088 19.2 0.2 0.74 9.7 0.1 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 CBZ34405.1 - 0.0013 18.3 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CBZ34405.1 - 0.0013 18.7 0.7 0.78 9.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 CBZ34405.1 - 0.0014 18.4 0.7 0.028 14.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 CBZ34405.1 - 0.0032 17.5 0.2 2.1 8.4 0.1 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 CBZ34405.1 - 0.0033 16.6 0.0 0.33 10.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 CBZ34405.1 - 0.0068 16.2 0.0 5.7 6.6 0.0 2.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 CBZ34405.1 - 0.011 15.5 0.0 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 CBZ34405.1 - 0.011 15.3 0.2 1 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CBZ34405.1 - 0.016 14.9 0.2 2.8 7.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 CBZ34405.1 - 0.016 14.4 0.1 0.66 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 CBZ34405.1 - 0.017 15.2 0.0 6.6 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CBZ34405.1 - 0.018 15.3 1.2 8.3 6.6 0.1 2.8 2 1 1 3 3 3 0 AAA domain TIP49 PF06068.13 CBZ34405.1 - 0.018 14.2 0.1 0.036 13.3 0.0 1.4 2 0 0 2 2 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 CBZ34405.1 - 0.019 14.3 0.5 1 8.6 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 CBZ34405.1 - 0.036 14.6 0.1 13 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBZ34405.1 - 0.04 13.8 0.0 1.6 8.6 0.0 2.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea TniB PF05621.11 CBZ34405.1 - 0.072 12.5 0.0 12 5.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein FtsK_SpoIIIE PF01580.18 CBZ34405.1 - 0.098 12.0 1.8 0.13 11.6 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 CBZ34405.1 - 0.15 11.8 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein HEAT PF02985.22 CBZ34406.1 - 1.1e-09 37.7 16.2 0.22 11.9 0.1 7.9 7 0 0 7 7 7 4 HEAT repeat HEAT_2 PF13646.6 CBZ34406.1 - 3.1e-08 33.9 8.6 0.0011 19.3 0.0 4.6 3 1 0 3 3 3 3 HEAT repeats Cnd1 PF12717.7 CBZ34406.1 - 0.00014 22.0 0.1 0.83 9.7 0.0 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CBZ34406.1 - 0.00053 20.5 0.1 4.4 8.0 0.1 3.8 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CBZ34406.1 - 0.0022 16.6 1.4 0.13 10.8 0.0 3.3 3 1 0 3 3 3 1 Adaptin N terminal region DBINO PF13892.6 CBZ34406.1 - 0.0076 16.6 2.1 0.019 15.3 2.1 1.6 1 0 0 1 1 1 1 DNA-binding domain Erf4 PF10256.9 CBZ34406.1 - 0.093 12.8 0.1 0.37 10.9 0.1 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family TFIIS_M PF07500.14 CBZ34407.1 - 1.1e-06 29.1 0.1 1.7e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain MLTR_LBD PF17765.1 CBZ34407.1 - 0.0069 16.5 0.3 0.012 15.7 0.3 1.6 1 0 0 1 1 1 1 MmyB-like transcription regulator ligand binding domain Zn_Tnp_IS1595 PF12760.7 CBZ34407.1 - 0.039 13.9 3.0 0.13 12.3 3.0 2.0 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TFIIS_C PF01096.18 CBZ34407.1 - 0.33 10.9 5.7 0.34 10.8 0.8 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) EccE PF11203.8 CBZ34407.1 - 1.8 8.9 9.5 0.61 10.4 4.1 2.3 1 1 1 2 2 2 0 Putative type VII ESX secretion system translocon, EccE TFIIS_M PF07500.14 CBZ34408.1 - 5.2e-16 59.1 0.2 9.2e-16 58.3 0.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CBZ34408.1 - 7.3e-15 54.5 4.5 1.3e-14 53.7 4.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Baculo_LEF5_C PF11792.8 CBZ34408.1 - 1.8e-05 24.3 1.0 6.7e-05 22.5 1.0 2.0 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain zf-DNL PF05180.12 CBZ34408.1 - 0.0054 16.6 0.4 0.013 15.5 0.4 1.6 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 CBZ34408.1 - 0.078 13.0 1.2 0.16 12.0 1.2 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like ubiquitin PF00240.23 CBZ34409.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family Pkinase PF00069.25 CBZ34410.1 - 7.7e-53 179.5 0.0 5.3e-52 176.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34410.1 - 1.9e-24 86.4 0.0 9.5e-19 67.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 CBZ34410.1 - 2e-15 56.9 0.2 4e-15 55.9 0.2 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBZ34410.1 - 6.5e-09 36.0 0.0 1.7e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 CBZ34410.1 - 0.00027 20.9 0.2 0.68 9.8 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ34410.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CAF1C_H4-bd PF12265.8 CBZ34411.1 - 2.6e-11 43.6 0.3 1.9e-10 40.9 0.1 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CBZ34411.1 - 0.00037 20.7 2.0 1 9.7 0.3 4.1 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CBZ34411.1 - 0.013 16.3 14.0 0.027 15.3 0.7 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat DEAD PF00270.29 CBZ34412.1 - 5e-33 114.3 0.6 1.7e-32 112.6 0.6 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ34412.1 - 2.6e-17 63.2 0.0 1.2e-16 61.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ34412.1 - 2.8e-07 30.7 0.0 9.3e-07 29.0 0.0 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CBZ34412.1 - 0.0067 15.2 0.3 0.024 13.4 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Stonin2_N PF12016.8 CBZ34413.1 - 0.18 11.2 6.4 0.037 13.5 2.9 1.6 2 0 0 2 2 2 0 Stonin 2 WD40 PF00400.32 CBZ34415.1 - 1.4e-07 32.0 3.9 0.04 14.8 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat tify PF06200.14 CBZ34415.1 - 0.0033 16.7 2.6 1.7 8.0 0.1 2.7 2 0 0 2 2 2 2 tify domain NIF PF03031.18 CBZ34416.1 - 3.2e-32 111.4 0.4 4.3e-32 111.0 0.4 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 CBZ34416.1 - 0.085 13.1 0.0 1 9.6 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase zf-RING_2 PF13639.6 CBZ34417.1 - 8.4e-05 22.8 8.9 0.00024 21.4 8.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBZ34417.1 - 0.019 15.2 8.2 0.063 13.6 8.2 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain FANCL_C PF11793.8 CBZ34417.1 - 0.032 14.4 4.4 0.085 13.0 4.4 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CBZ34417.1 - 0.062 13.4 5.6 0.14 12.2 4.4 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CBZ34417.1 - 0.13 12.1 7.2 0.31 10.9 7.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4226 PF10774.9 CBZ34417.1 - 0.15 12.3 2.0 1.5 9.2 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) zf-C3HC4_3 PF13920.6 CBZ34417.1 - 0.83 9.6 4.4 1.9 8.4 4.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 CBZ34417.1 - 0.84 9.8 6.5 2.1 8.5 6.5 1.8 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CBZ34417.1 - 2.7 8.4 6.7 1.1 9.6 3.3 2.2 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_2 PF13923.6 CBZ34417.1 - 3.5 7.6 7.7 11 5.9 7.7 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AF-4 PF05110.13 CBZ34417.1 - 7.2 4.6 10.5 12 3.9 10.5 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Fumerase_C PF05683.12 CBZ34419.1 - 1.8e-86 288.7 0.0 3.3e-86 287.9 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 CBZ34419.1 - 2.3e-79 266.6 0.0 3e-79 266.3 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) Rsm22 PF09243.10 CBZ34420.1 - 7.8e-30 104.1 1.2 2.9e-17 62.8 0.1 3.1 3 0 0 3 3 3 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 CBZ34420.1 - 0.096 12.5 0.0 1.6 8.5 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ34420.1 - 0.2 12.4 0.0 9.4 7.1 0.0 2.9 2 0 0 2 2 2 0 Methyltransferase domain Phosphodiest PF01663.22 CBZ34421.1 - 9.9e-10 38.5 0.0 2.1e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CBZ34421.1 - 0.0099 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Mg_trans_NIPA PF05653.14 CBZ34421.1 - 0.018 14.2 0.2 0.039 13.1 0.2 1.5 1 0 0 1 1 1 0 Magnesium transporter NIPA Sulfatase PF00884.23 CBZ34421.1 - 0.036 13.4 0.1 0.064 12.6 0.1 1.3 1 0 0 1 1 1 0 Sulfatase Tudor_3 PF18115.1 CBZ34422.1 - 0.081 12.8 0.0 8 6.4 0.0 2.5 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain DUF2561 PF10812.8 CBZ34424.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Aminotran_1_2 PF00155.21 CBZ34425.1 - 2.6e-69 234.1 0.0 3e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II RF-1 PF00472.20 CBZ34427.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 RF-1 domain TPR_2 PF07719.17 CBZ34428.1 - 0.02 14.9 0.1 6 7.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat SET PF00856.28 CBZ34428.1 - 0.089 13.2 0.3 0.23 11.8 0.3 1.8 1 1 0 1 1 1 0 SET domain AAA_16 PF13191.6 CBZ34429.1 - 0.03 14.7 0.0 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_C12 PF01088.21 CBZ34430.1 - 3.1e-57 193.7 0.0 4.3e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CBZ34430.1 - 3.8e-12 45.9 0.4 8e-12 44.9 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Stealth_CR3 PF17102.5 CBZ34432.1 - 0.01 15.7 0.5 0.01 15.7 0.5 2.7 3 0 0 3 3 3 0 Stealth protein CR3, conserved region 3 Peptidase_M50B PF13398.6 CBZ34434.1 - 0.097 12.3 0.9 0.14 11.8 0.9 1.4 1 1 0 1 1 1 0 Peptidase M50B-like Ketoacyl-synt_2 PF13723.6 CBZ34434.1 - 1.7 8.3 5.1 2.3 7.8 5.1 1.2 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain ThiF PF00899.21 CBZ34435.1 - 1.2e-32 113.3 0.1 1.2e-32 113.2 0.1 1.2 1 0 0 1 1 1 1 ThiF family GTP-bdg_N PF13167.6 CBZ34435.1 - 0.032 14.9 0.0 0.077 13.7 0.0 1.6 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal Kelch_4 PF13418.6 CBZ34437.1 - 3.8e-28 97.2 5.5 2.3e-07 30.7 0.0 7.1 6 2 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ34437.1 - 2.9e-23 81.4 0.5 8.2e-09 35.3 0.1 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 CBZ34437.1 - 3.1e-17 62.2 0.0 0.0016 18.7 0.0 6.0 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.15 CBZ34437.1 - 6.4e-10 38.6 0.1 0.011 15.7 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CBZ34437.1 - 1.8e-08 34.4 19.3 0.0006 20.0 0.1 8.8 10 0 0 10 10 10 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ34437.1 - 3.5e-06 26.5 7.8 0.028 14.0 0.0 5.9 7 0 0 7 7 7 2 Kelch motif LRR_4 PF12799.7 CBZ34438.1 - 8.2e-46 153.2 63.1 1.8e-06 28.2 0.1 14.2 9 4 3 14 14 14 14 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ34438.1 - 1.9e-43 146.1 63.7 5.5e-08 32.5 0.2 11.0 7 3 4 11 11 11 10 Leucine rich repeat LRR_9 PF14580.6 CBZ34438.1 - 6.5e-36 123.5 21.4 1e-09 38.1 0.3 8.0 6 2 2 8 8 8 7 Leucine-rich repeat LRR_6 PF13516.6 CBZ34438.1 - 3.3e-07 29.8 38.5 4.5 7.6 0.1 15.9 16 1 1 17 17 17 3 Leucine Rich repeat Pico_P1A PF02226.16 CBZ34438.1 - 0.17 11.9 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) Dicer_dimer PF03368.14 CBZ34439.1 - 0.16 12.1 0.1 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 Dicer dimerisation domain Spectrin PF00435.21 CBZ34440.1 - 0.0025 18.3 8.8 0.0025 18.3 8.8 5.0 5 2 1 6 6 6 1 Spectrin repeat DUF1664 PF07889.12 CBZ34440.1 - 0.15 12.1 8.1 0.2 11.7 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 CBZ34440.1 - 2.6 6.8 36.3 1.7 7.4 4.6 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein DnaJ PF00226.31 CBZ34441.1 - 9.7e-16 57.7 1.7 2e-15 56.7 1.7 1.6 1 0 0 1 1 1 1 DnaJ domain TFIID-31kDa PF02291.15 CBZ34441.1 - 0.0034 17.4 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Metal_resist PF13801.6 CBZ34441.1 - 2.1 8.6 6.3 0.96 9.6 0.1 3.1 3 0 0 3 3 3 0 Heavy-metal resistance ENT PF03735.14 CBZ34442.1 - 0.00059 19.8 0.2 0.0032 17.5 0.0 2.0 2 0 0 2 2 2 1 ENT domain TRM13 PF05206.14 CBZ34443.1 - 5.1e-14 52.4 0.1 8.2e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase TRM13 Methyltransf_32 PF13679.6 CBZ34443.1 - 3.5e-06 27.1 0.0 1.3e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain NolV PF06635.12 CBZ34444.1 - 0.0075 15.7 1.1 0.11 11.8 0.1 2.2 2 0 0 2 2 2 2 Nodulation protein NolV LapA_dom PF06305.11 CBZ34445.1 - 0.0013 18.6 0.2 0.0017 18.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain WBP-1 PF11669.8 CBZ34445.1 - 0.0025 18.4 0.0 0.0038 17.8 0.0 1.4 1 0 0 1 1 1 1 WW domain-binding protein 1 DUF4381 PF14316.6 CBZ34445.1 - 0.14 12.4 0.1 0.18 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SIT PF15330.6 CBZ34446.1 - 0.0037 17.7 0.0 0.004 17.6 0.0 1.1 1 0 0 1 1 1 1 SHP2-interacting transmembrane adaptor protein, SIT EphA2_TM PF14575.6 CBZ34446.1 - 0.014 16.3 0.0 0.014 16.2 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 CBZ34446.1 - 0.023 14.7 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Protocadherin Phage_ASH PF10554.9 CBZ34447.1 - 0.06 13.7 0.3 0.14 12.5 0.3 1.5 1 0 0 1 1 1 0 Ash protein family Npa1 PF11707.8 CBZ34449.1 - 5.8e-08 32.5 0.0 1.6e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CBZ34449.1 - 6.3e-07 29.2 0.0 3.5e-06 26.8 0.0 2.5 1 1 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 MOR2-PAG1_N PF14222.6 CBZ34449.1 - 0.031 13.2 0.2 0.064 12.2 0.2 1.4 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Arm PF00514.23 CBZ34449.1 - 0.56 10.3 2.4 2.8 8.1 0.7 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SNF2_N PF00176.23 CBZ34450.1 - 8.4e-32 110.2 0.0 1.3e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ34450.1 - 1.1e-09 38.6 0.0 4.5e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ34450.1 - 2.9e-07 30.7 0.0 5.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CBZ34450.1 - 0.082 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 Flavivirus DEAD domain TniB PF05621.11 CBZ34450.1 - 0.12 11.8 0.2 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein UCH PF00443.29 CBZ34451.1 - 1.2e-45 156.0 0.0 2.1e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ34451.1 - 2.3e-09 37.3 0.0 0.00018 21.2 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ATP-synt_C PF00137.21 CBZ34452.1 - 1.8e-06 28.2 14.5 1.8e-06 28.2 14.5 1.6 2 0 0 2 2 2 1 ATP synthase subunit C Kinesin PF00225.23 CBZ34453.1 - 1.5e-90 303.5 0.0 2e-90 303.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ34453.1 - 6.8e-17 61.8 0.0 1.4e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Peptidase_C97 PF05903.14 CBZ34454.1 - 3.1e-29 101.8 0.0 9.7e-29 100.1 0.0 1.7 2 0 0 2 2 2 1 PPPDE putative peptidase domain LRAT PF04970.13 CBZ34454.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Pkinase PF00069.25 CBZ34456.1 - 9e-35 120.3 0.0 1.3e-33 116.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34456.1 - 3.6e-10 39.6 0.0 1.7e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sugar_tr PF00083.24 CBZ34457.1 - 1.8e-128 429.2 34.7 2.2e-128 429.0 34.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBZ34457.1 - 2.4e-30 105.7 80.8 4.2e-29 101.6 42.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF523 PF04463.12 CBZ34460.1 - 6.6e-14 52.1 0.0 8e-08 32.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF523) zf-Tim10_DDP PF02953.15 CBZ34461.1 - 0.00021 20.9 2.7 0.00029 20.4 2.7 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger SRP54 PF00448.22 CBZ34462.1 - 5.1e-74 248.2 1.1 9.3e-74 247.3 1.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CBZ34462.1 - 4.4e-25 88.2 1.6 4.4e-25 88.2 1.6 4.2 4 1 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 CBZ34462.1 - 2.7e-13 49.9 3.4 3e-13 49.8 1.4 2.2 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CBZ34462.1 - 3.1e-07 30.2 0.5 1.1e-06 28.3 0.5 2.0 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CBZ34462.1 - 9.5e-05 22.6 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CBZ34462.1 - 9.7e-05 22.8 1.4 0.00015 22.2 0.2 2.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CBZ34462.1 - 0.0015 18.3 0.1 0.0047 16.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CBZ34462.1 - 0.0015 17.6 0.1 0.006 15.6 0.0 1.9 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 CBZ34462.1 - 0.0031 16.8 0.1 0.0063 15.8 0.1 1.4 1 0 0 1 1 1 1 Zeta toxin Methyltransf_24 PF13578.6 CBZ34462.1 - 0.0033 18.4 0.0 0.034 15.2 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain CbiA PF01656.23 CBZ34462.1 - 0.0043 17.1 0.0 0.017 15.2 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.10 CBZ34462.1 - 0.01 15.3 1.2 2.7 7.4 1.2 2.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 CBZ34462.1 - 0.011 15.5 0.5 0.057 13.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBZ34462.1 - 0.014 15.7 0.3 0.12 12.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.20 CBZ34462.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Fe-ADH PF00465.19 CBZ34462.1 - 0.017 14.0 0.0 0.035 12.9 0.0 1.5 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase GhoS PF11080.8 CBZ34462.1 - 0.018 15.0 0.2 15 5.7 0.1 3.4 4 0 0 4 4 3 0 Endoribonuclease GhoS CLP1_P PF16575.5 CBZ34462.1 - 0.022 14.6 0.5 0.49 10.2 0.0 2.4 1 1 1 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 CBZ34462.1 - 0.042 13.6 0.2 0.28 10.9 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MipZ PF09140.11 CBZ34462.1 - 0.064 12.5 0.1 1.5 8.1 0.1 2.3 1 1 0 1 1 1 0 ATPase MipZ Dynamin_N PF00350.23 CBZ34462.1 - 0.067 13.2 1.1 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 CBZ34462.1 - 0.071 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_31 PF13614.6 CBZ34462.1 - 0.099 12.6 1.4 4 7.3 0.0 2.7 2 1 1 3 3 2 0 AAA domain SWI2_SNF2 PF18766.1 CBZ34462.1 - 0.1 12.2 1.0 2.2 7.9 0.0 2.3 1 1 1 2 2 2 0 SWI2/SNF2 ATPase ATPase PF06745.13 CBZ34462.1 - 0.12 11.7 1.8 0.35 10.2 0.1 2.4 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.15 CBZ34462.1 - 0.16 11.9 3.4 11 6.0 3.4 2.5 1 1 0 1 1 1 0 NTPase DUF2209 PF09974.9 CBZ34462.1 - 0.17 12.2 1.7 0.53 10.6 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) MMR_HSR1 PF01926.23 CBZ34462.1 - 0.22 11.6 1.9 1.2 9.2 1.0 2.6 2 1 0 2 2 1 0 50S ribosome-binding GTPase HAD_SAK_2 PF18143.1 CBZ34464.1 - 7.5e-31 107.3 0.6 1.2e-30 106.6 0.0 1.6 2 0 0 2 2 2 1 HAD domain in Swiss Army Knife RNA repair proteins Gp-FAR-1 PF05823.12 CBZ34464.1 - 0.0018 18.6 0.9 0.0029 18.0 0.9 1.4 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) APG6_N PF17675.1 CBZ34464.1 - 0.0056 17.2 1.0 0.0056 17.2 1.0 1.7 2 0 0 2 2 2 1 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 CBZ34464.1 - 0.0074 16.3 3.7 0.0074 16.3 3.7 1.9 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 CBZ34464.1 - 0.17 12.2 0.6 0.34 11.2 0.6 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DivIC PF04977.15 CBZ34464.1 - 4.9 7.0 7.1 0.87 9.4 3.1 1.8 2 0 0 2 2 2 0 Septum formation initiator Cnn_1N PF07989.11 CBZ34464.1 - 5.4 7.2 7.4 15 5.8 2.2 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 CENP-H PF05837.12 CBZ34464.1 - 5.4 7.5 10.0 27 5.2 10.0 2.0 1 1 0 1 1 1 0 Centromere protein H (CENP-H) KELK PF15796.5 CBZ34464.1 - 9.5 6.8 12.8 0.081 13.4 2.4 2.5 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SNF2_N PF00176.23 CBZ34465.1 - 1.5e-57 194.9 0.0 2.6e-57 194.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ34465.1 - 4.7e-17 62.3 0.0 1.6e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ34465.1 - 8.3e-10 38.9 0.0 1.7e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBZ34465.1 - 1.2e-08 35.0 0.0 2.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cwf_Cwc_15 PF04889.12 CBZ34465.1 - 4.4 7.0 7.9 21 4.8 0.0 2.6 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Malic_M PF03949.15 CBZ34466.1 - 1.1e-82 277.2 0.3 1.4e-82 276.8 0.3 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CBZ34466.1 - 1.9e-67 226.6 0.0 5.8e-67 225.0 0.0 1.8 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 CBZ34467.1 - 5.9e-84 281.4 0.1 1.8e-83 279.7 0.1 1.7 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.19 CBZ34467.1 - 2e-68 229.7 0.0 3e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain KN17_SH3 PF18131.1 CBZ34469.1 - 0.14 12.3 0.3 0.27 11.4 0.3 1.3 1 0 0 1 1 1 0 KN17 SH3-like C-terminal domain PTS_2-RNA PF01885.16 CBZ34471.1 - 9.1e-56 188.8 0.0 1.3e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RNase_T PF00929.24 CBZ34471.1 - 1.9e-20 74.0 0.0 3.4e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Syja_N PF02383.18 CBZ34472.1 - 1e-54 186.0 0.0 1.6e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain DUF547 PF04784.14 CBZ34472.1 - 0.00018 21.5 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF547 Ax_dynein_light PF10211.9 CBZ34474.1 - 9.5e-78 260.4 4.6 1.1e-77 260.2 4.6 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Filament PF00038.21 CBZ34474.1 - 0.00052 19.7 9.0 0.002 17.8 3.7 2.0 1 1 1 2 2 2 1 Intermediate filament protein APG6_N PF17675.1 CBZ34474.1 - 0.00067 20.2 7.7 0.00067 20.2 7.7 1.7 2 0 0 2 2 2 1 Apg6 coiled-coil region Mei5 PF10376.9 CBZ34474.1 - 0.0052 16.7 1.8 0.0071 16.2 1.8 1.3 1 0 0 1 1 1 1 Double-strand recombination repair protein Jnk-SapK_ap_N PF09744.9 CBZ34474.1 - 0.013 15.8 13.9 0.53 10.5 13.9 2.1 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.21 CBZ34474.1 - 0.02 15.0 2.3 0.02 15.0 2.3 1.9 2 0 0 2 2 2 0 bZIP transcription factor CENP-H PF05837.12 CBZ34474.1 - 0.046 14.1 5.8 0.1 13.0 5.8 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) HALZ PF02183.18 CBZ34474.1 - 0.071 13.4 2.9 0.27 11.5 0.8 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.11 CBZ34474.1 - 0.077 13.6 4.2 0.14 12.7 4.2 1.5 1 0 0 1 1 1 0 Syntaxin 6, N-terminal End3 PF12761.7 CBZ34474.1 - 0.11 12.6 5.9 0.053 13.7 3.4 1.6 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Spc24 PF08286.11 CBZ34474.1 - 0.17 12.2 5.5 0.18 12.0 3.9 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FadA PF09403.10 CBZ34474.1 - 0.21 12.1 5.6 0.56 10.7 5.6 1.8 1 0 0 1 1 1 0 Adhesion protein FadA ERM PF00769.19 CBZ34474.1 - 0.53 10.1 14.5 0.025 14.4 9.2 1.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DivIC PF04977.15 CBZ34474.1 - 2.1 8.2 8.6 0.77 9.6 4.2 2.3 2 1 0 2 2 2 0 Septum formation initiator TIM PF00121.18 CBZ34475.1 - 6.9e-89 297.4 0.1 7.7e-89 297.2 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase EMP24_GP25L PF01105.24 CBZ34478.1 - 0.0026 17.7 0.0 0.0031 17.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF5564 PF17719.1 CBZ34478.1 - 0.058 13.5 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5564) PRIMA1 PF16101.5 CBZ34479.1 - 0.007 16.4 0.3 0.015 15.3 0.3 1.5 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 DNA_pol_A PF00476.20 CBZ34480.1 - 3.9e-49 167.7 0.2 8.9e-49 166.5 0.2 1.6 1 1 0 1 1 1 1 DNA polymerase family A P4Ha_N PF08336.11 CBZ34480.1 - 0.2 11.7 0.1 0.38 10.8 0.1 1.4 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region MCM PF00493.23 CBZ34482.1 - 2.4e-88 295.0 0.1 3.7e-88 294.4 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ34482.1 - 3.6e-34 117.3 0.4 8.3e-34 116.2 0.4 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ34482.1 - 2e-23 82.6 1.6 1.4e-22 79.9 1.6 2.4 1 1 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBZ34482.1 - 1.2e-09 38.7 0.0 3.3e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBZ34482.1 - 1.7e-07 30.8 0.0 3.7e-06 26.5 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBZ34482.1 - 0.00024 21.0 0.0 0.00064 19.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ34482.1 - 0.00038 20.5 0.0 0.001 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PUA PF01472.20 CBZ34482.1 - 0.0044 17.0 1.8 0.66 10.0 0.2 2.6 2 0 0 2 2 2 2 PUA domain Sigma54_activat PF00158.26 CBZ34482.1 - 0.034 13.9 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF844 PF05815.11 CBZ34482.1 - 0.087 12.0 0.5 0.64 9.2 0.1 2.4 2 1 0 2 2 2 0 Baculovirus protein of unknown function (DUF844) UBA PF00627.31 CBZ34482.1 - 0.16 11.9 0.1 0.55 10.2 0.1 2.0 1 0 0 1 1 1 0 UBA/TS-N domain MTS PF05175.14 CBZ34483.1 - 0.0044 16.6 0.0 0.012 15.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 CBZ34483.1 - 0.0053 17.4 0.1 0.037 14.7 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain DUF2489 PF10675.9 CBZ34484.1 - 0.084 12.8 0.3 0.16 11.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) ANAPC4_WD40 PF12894.7 CBZ34484.1 - 0.092 13.1 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Importin_rep_6 PF18829.1 CBZ34485.1 - 0.098 12.8 0.2 6.7 6.9 0.5 2.1 1 1 1 2 2 2 0 Importin repeat 6 RabGAP-TBC PF00566.18 CBZ34486.1 - 5.4e-10 39.3 2.1 2.1e-09 37.4 2.2 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RFC1 PF08519.12 CBZ34490.1 - 4.8e-43 147.0 0.0 1.3e-42 145.6 0.0 1.8 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CBZ34490.1 - 7.6e-12 45.8 0.0 2e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CBZ34490.1 - 4.2e-08 33.3 0.0 7.9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain Zeta_toxin PF06414.12 CBZ34490.1 - 0.00014 21.2 0.0 0.00034 19.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.6 CBZ34490.1 - 0.00054 20.0 0.0 0.0017 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ34490.1 - 0.00071 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBZ34490.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ34490.1 - 0.0026 18.2 0.0 0.0071 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ34490.1 - 0.0088 16.3 0.0 0.03 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ34490.1 - 0.011 16.0 0.2 0.59 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBZ34490.1 - 0.033 14.6 0.0 0.081 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_assoc_2 PF16193.5 CBZ34490.1 - 0.034 14.5 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain AAA_6 PF12774.7 CBZ34490.1 - 0.067 12.2 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region NTPase_1 PF03266.15 CBZ34490.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.6 CBZ34490.1 - 0.097 13.2 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ34490.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PAP1 PF08601.10 CBZ34490.1 - 5.1 6.7 22.5 8.4 6.0 22.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 DUF572 PF04502.13 CBZ34490.1 - 9.9 5.7 15.0 15 5.1 15.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Mnd1 PF03962.15 CBZ34492.1 - 6.7e-17 61.5 0.0 1.2e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 CBZ34492.1 - 3.2e-06 27.1 0.0 4.8e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 Leucine zipper with capping helix domain FUSC PF04632.12 CBZ34492.1 - 1.1 7.7 12.8 1.5 7.3 12.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Kelch_6 PF13964.6 CBZ34493.1 - 6.9e-16 57.9 3.8 3.3e-05 24.0 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 CBZ34493.1 - 3.4e-13 49.4 4.8 1.9e-05 24.5 0.0 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ34493.1 - 3e-10 39.5 3.5 0.00021 20.8 0.0 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBZ34493.1 - 1.1e-08 34.8 1.8 0.0012 18.8 0.0 3.4 4 0 0 4 4 4 2 Kelch motif F-box PF00646.33 CBZ34493.1 - 9.4e-06 25.4 0.3 2.4e-05 24.1 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CBZ34493.1 - 1e-05 25.3 0.3 2.2e-05 24.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like Kelch_3 PF13415.6 CBZ34493.1 - 0.00041 20.6 0.7 0.62 10.4 0.0 3.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_2 PF07646.15 CBZ34493.1 - 0.0013 18.6 0.0 1.5 8.9 0.0 3.5 3 0 0 3 3 3 1 Kelch motif TctA PF01970.16 CBZ34493.1 - 0.052 12.3 0.0 0.086 11.5 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family LRR_4 PF12799.7 CBZ34494.1 - 2.1e-12 47.0 11.9 4.1e-07 30.2 0.5 3.6 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ34494.1 - 1.4e-09 37.7 0.9 8.3e-09 35.2 0.9 2.1 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CBZ34494.1 - 1.7e-09 37.3 6.7 6e-07 29.1 0.6 3.1 2 1 2 4 4 4 3 Leucine rich repeat FNIP PF05725.12 CBZ34494.1 - 0.033 14.4 0.3 0.085 13.0 0.3 1.7 1 0 0 1 1 1 0 FNIP Repeat LRR_1 PF00560.33 CBZ34494.1 - 0.45 11.2 5.1 20 6.2 0.8 3.6 2 2 0 2 2 2 0 Leucine Rich Repeat SNF2_N PF00176.23 CBZ34496.1 - 3.3e-35 121.5 0.0 4e-34 117.9 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ34496.1 - 1.6e-14 54.2 0.0 5e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ34496.1 - 3.3e-05 23.9 0.0 0.0004 20.4 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CBZ34496.1 - 0.0046 16.7 0.5 0.016 14.9 0.0 2.1 3 0 0 3 3 3 1 SWI2/SNF2 ATPase ParD PF09386.10 CBZ34496.1 - 0.088 13.2 0.3 0.29 11.6 0.3 1.9 1 0 0 1 1 1 0 Antitoxin ParD HCV_NS4b PF01001.19 CBZ34496.1 - 0.87 9.2 5.1 3.4 7.2 0.4 2.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4b Dishevelled PF02377.15 CBZ34496.1 - 4.9 7.6 10.3 0.25 11.8 3.5 2.3 2 0 0 2 2 2 0 Dishevelled specific domain AKAP7_NLS PF10469.9 CBZ34497.1 - 2.6e-15 56.9 0.0 5.9e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DnaJ PF00226.31 CBZ34499.1 - 2.8e-14 53.0 0.1 2.1e-13 50.2 0.0 2.4 3 0 0 3 3 3 1 DnaJ domain HA2 PF04408.23 CBZ34501.1 - 1.8e-13 50.7 1.2 4.2e-13 49.5 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBZ34501.1 - 1.5e-10 41.3 0.0 3.5e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBZ34501.1 - 4.2e-10 39.9 0.0 9.5e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ34501.1 - 1e-05 25.4 0.0 2.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CBZ34501.1 - 0.00085 19.1 0.1 0.0027 17.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ34501.1 - 0.0019 18.5 0.6 0.015 15.5 0.6 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBZ34501.1 - 0.0069 16.7 0.3 0.028 14.7 0.1 1.9 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CBZ34501.1 - 0.047 14.2 0.0 0.14 12.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 CBZ34501.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 KaiC cobW PF02492.19 CBZ34501.1 - 0.19 11.3 0.4 0.76 9.3 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FH2 PF02181.23 CBZ34502.1 - 3.1e-51 174.7 0.0 4.1e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain PTEN_C2 PF10409.9 CBZ34502.1 - 0.0012 18.6 0.0 0.0037 17.0 0.0 1.7 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein KdpC PF02669.15 CBZ34503.1 - 0.087 12.6 0.2 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 K+-transporting ATPase, c chain EF-hand_6 PF13405.6 CBZ34503.1 - 0.11 12.5 0.0 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain APG6_N PF17675.1 CBZ34505.1 - 0.0007 20.1 7.8 0.0007 20.1 7.8 6.9 5 2 1 6 6 6 2 Apg6 coiled-coil region ATG16 PF08614.11 CBZ34505.1 - 0.0068 16.6 8.5 0.0068 16.6 8.5 6.5 3 1 2 5 5 5 3 Autophagy protein 16 (ATG16) CC2-LZ PF16516.5 CBZ34505.1 - 0.013 15.9 7.5 0.013 15.9 7.5 8.6 6 2 3 9 9 9 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF573 PF04504.14 CBZ34505.1 - 0.27 11.9 2.3 0.76 10.5 0.9 2.5 1 1 0 1 1 1 0 Protein of unknown function, DUF573 Pox_A_type_inc PF04508.12 CBZ34505.1 - 1.4 8.9 5.8 18 5.4 0.1 4.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat ThiS PF02597.20 CBZ34505.1 - 2.6 8.8 4.1 5.2 7.8 0.1 3.6 3 1 0 3 3 3 0 ThiS family EF-hand_1 PF00036.32 CBZ34506.1 - 0.045 13.3 0.0 10 5.9 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 CBZ34506.1 - 0.17 11.9 0.0 39 4.5 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain RNA_pol PF00940.19 CBZ34507.1 - 1.5e-131 439.1 0.0 2.6e-131 438.3 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase Syntaxin PF00804.25 CBZ34508.1 - 2 8.1 11.1 2.9 7.5 4.3 2.6 2 0 0 2 2 2 0 Syntaxin Prominin PF05478.11 CBZ34508.1 - 3.6 5.4 4.7 5.5 4.8 4.7 1.1 1 0 0 1 1 1 0 Prominin Adaptin_binding PF10199.9 CBZ34509.1 - 6.7e-05 23.5 0.0 0.21 12.2 0.1 3.5 3 1 0 3 3 3 2 Alpha and gamma adaptin binding protein p34 SURF6 PF04935.12 CBZ34510.1 - 2.7e-16 60.0 12.2 2.7e-16 60.0 12.2 1.8 1 1 1 2 2 2 1 Surfeit locus protein 6 Bax1-I PF01027.20 CBZ34511.1 - 5.2e-41 140.8 18.7 5.2e-41 140.8 18.7 1.6 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.7 CBZ34511.1 - 4.1e-09 36.4 7.2 5.9e-09 35.8 7.2 1.2 1 0 0 1 1 1 1 Bax inhibitor 1 like YL1 PF05764.13 CBZ34512.1 - 1.7e-10 41.4 30.1 4.5e-09 36.8 30.3 2.0 1 1 1 2 2 2 2 YL1 nuclear protein MBF1 PF08523.10 CBZ34512.1 - 2.1 8.9 8.8 1.1 9.7 3.1 2.8 2 1 0 2 2 2 0 Multiprotein bridging factor 1 Spt5_N PF11942.8 CBZ34512.1 - 3.8 8.5 30.8 3.4 8.7 4.1 2.8 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SUI1 PF01253.22 CBZ34513.1 - 1.4e-21 76.8 0.2 1.8e-21 76.4 0.2 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 RRM_1 PF00076.22 CBZ34514.1 - 0.0041 16.9 0.2 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spuma_A9PTase PF03539.14 CBZ34514.1 - 0.099 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) PHD PF00628.29 CBZ34515.1 - 3e-05 23.8 10.7 3e-05 23.8 10.7 1.8 2 0 0 2 2 2 1 PHD-finger Acetyltransf_7 PF13508.7 CBZ34515.1 - 4.5e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBZ34515.1 - 0.01 15.8 0.2 0.39 10.7 0.2 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBZ34515.1 - 0.17 12.0 0.5 1.5 8.9 0.5 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PHD_4 PF16866.5 CBZ34515.1 - 8.6 6.5 11.6 0.18 11.9 4.7 1.8 2 0 0 2 2 2 0 PHD-finger Amastin PF07344.11 CBZ34517.1 - 5.6e-20 71.8 4.4 7.3e-20 71.4 4.4 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_C7 PF01830.18 CBZ34517.1 - 0.0052 16.2 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase C7 family TMEM100 PF16311.5 CBZ34517.1 - 0.16 11.5 2.6 0.24 11.0 2.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 Amastin PF07344.11 CBZ34518.1 - 7e-43 146.1 13.2 8.5e-43 145.9 13.2 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1345 PF07077.11 CBZ34518.1 - 0.46 10.2 8.1 0.035 13.8 1.9 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1345) Amastin PF07344.11 CBZ34519.1 - 8.6e-47 158.8 15.5 1e-46 158.6 15.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF1345 PF07077.11 CBZ34519.1 - 1.9 8.2 9.4 0.07 12.8 2.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1345) Caveolin PF01146.17 CBZ34519.1 - 7.5 6.5 11.8 0.77 9.7 5.7 2.1 2 0 0 2 2 2 0 Caveolin Amastin PF07344.11 CBZ34520.1 - 4.9e-13 49.2 0.7 8e-13 48.5 0.7 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein Peptidase_C7 PF01830.18 CBZ34520.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase C7 family WASH-7_mid PF14744.6 CBZ34521.1 - 1.7e-131 438.4 0.1 2.9e-131 437.7 0.1 1.3 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.6 CBZ34521.1 - 6.6e-47 159.4 0.3 1.6e-46 158.2 0.3 1.7 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal WASH-7_N PF14745.6 CBZ34521.1 - 1.8e-28 99.4 0.0 1.1e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 WASH complex subunit 7, N-terminal DnaJ PF00226.31 CBZ34522.1 - 6.6e-10 39.0 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Glyco_hydro_9 PF00759.19 CBZ34522.1 - 0.027 13.9 0.2 0.089 12.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 9 PAS PF00989.25 CBZ34522.1 - 0.091 12.8 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold BLUF PF04940.12 CBZ34523.1 - 0.083 13.0 0.1 0.53 10.4 0.0 2.1 2 0 0 2 2 2 0 Sensors of blue-light using FAD Pro_isomerase PF00160.21 CBZ34524.1 - 1.1e-19 71.2 0.0 1.6e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TRAPP PF04051.16 CBZ34525.1 - 2e-05 24.4 0.0 2.4e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component LRR_9 PF14580.6 CBZ34525.1 - 0.16 11.4 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeat GTP_EFTU PF00009.27 CBZ34527.1 - 5.7e-24 84.7 0.3 3.8e-22 78.8 0.3 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ34527.1 - 1.1e-11 44.9 0.0 2.8e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBZ34527.1 - 2.4e-05 24.1 0.1 0.00015 21.6 0.0 2.2 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation IF-2 PF11987.8 CBZ34527.1 - 8.6e-05 22.6 0.0 0.00022 21.3 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 RsgA_GTPase PF03193.16 CBZ34527.1 - 0.00041 20.3 0.1 0.059 13.3 0.4 2.5 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CBZ34527.1 - 0.021 14.9 1.2 0.12 12.4 0.0 2.5 2 1 1 3 3 3 0 Dynamin family Roc PF08477.13 CBZ34527.1 - 0.027 14.7 0.0 0.084 13.1 0.0 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF678 PF05077.12 CBZ34527.1 - 0.041 14.0 0.3 0.1 12.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF678) FeoB_N PF02421.18 CBZ34527.1 - 0.041 13.4 0.1 0.12 11.9 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 CBZ34527.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1484 PF07363.11 CBZ34527.1 - 0.14 13.2 2.0 0.15 13.1 0.3 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF1484) cobW PF02492.19 CBZ34527.1 - 0.16 11.5 3.7 0.36 10.4 0.5 3.0 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain IQ PF00612.27 CBZ34528.1 - 3.4e-06 26.4 45.9 0.001 18.7 0.4 7.1 7 0 0 7 7 7 5 IQ calmodulin-binding motif Dymeclin PF09742.9 CBZ34529.1 - 3.3e-57 194.3 0.0 4.5e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 CBZ34529.1 - 7.5e-29 100.5 4.7 1.3e-13 50.0 2.6 4.2 3 2 0 3 3 3 3 High-temperature-induced dauer-formation protein Hist_deacetyl PF00850.19 CBZ34530.1 - 6.1e-73 246.0 0.2 7.8e-73 245.6 0.2 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MAGI_u5 PF16666.5 CBZ34530.1 - 2.8 8.1 8.7 5.2 7.2 8.7 1.3 1 0 0 1 1 1 0 Unstructured region on MAGI EF-hand_7 PF13499.6 CBZ34531.1 - 9.8e-22 77.2 3.4 1.6e-13 50.9 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ34531.1 - 2.9e-18 64.0 4.0 4.3e-05 22.8 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBZ34531.1 - 1.9e-16 58.5 4.9 0.00034 20.3 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CBZ34531.1 - 3.8e-13 48.3 3.3 2.7e-05 23.5 0.1 4.3 4 0 0 4 4 4 3 EF hand zf-C3HC4_3 PF13920.6 CBZ34531.1 - 2.8e-11 43.1 5.7 2.8e-11 43.1 5.7 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) EF-hand_8 PF13833.6 CBZ34531.1 - 5.7e-09 35.7 3.4 0.00081 19.2 0.3 3.7 3 1 1 4 4 4 2 EF-hand domain pair zf-C3HC4_2 PF13923.6 CBZ34531.1 - 8.6e-09 35.1 9.5 2.7e-08 33.5 9.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ34531.1 - 2.1e-08 34.1 2.1 2.1e-08 34.1 2.1 3.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ34531.1 - 1.3e-07 31.5 5.9 1.3e-07 31.5 5.9 2.2 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBZ34531.1 - 1.7e-07 31.0 4.4 1.7e-07 31.0 4.4 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ34531.1 - 1.6e-06 28.3 8.2 1.6e-06 28.3 8.2 2.5 2 1 0 2 2 1 1 Ring finger domain SPARC_Ca_bdg PF10591.9 CBZ34531.1 - 1.7e-06 28.4 0.0 9.8e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Prok-RING_4 PF14447.6 CBZ34531.1 - 6.1e-06 26.0 6.7 6.1e-06 26.0 6.7 2.1 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CBZ34531.1 - 1.3e-05 25.0 2.5 3.6e-05 23.5 2.5 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CBZ34531.1 - 0.00059 19.9 4.8 0.00059 19.9 4.8 2.7 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CBZ34531.1 - 0.0041 16.8 4.6 0.022 14.5 3.2 2.4 2 0 0 2 2 2 1 RING-like zinc finger EF-hand_10 PF14788.6 CBZ34531.1 - 0.056 13.3 0.3 27 4.7 0.0 3.3 3 1 1 4 4 4 0 EF hand EF-hand_11 PF08976.11 CBZ34531.1 - 0.072 14.0 0.2 16 6.5 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain zf-RING_10 PF16685.5 CBZ34531.1 - 1.2 9.3 11.4 0.78 9.9 9.0 1.9 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 CBZ34532.1 - 3.3e-11 42.9 5.3 3.3e-11 42.9 5.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ34532.1 - 6.2e-09 35.5 9.5 1.6e-08 34.2 9.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ34532.1 - 1.3e-08 34.8 2.1 1.3e-08 34.8 2.1 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ34532.1 - 7.6e-08 32.2 5.9 7.6e-08 32.2 5.9 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CBZ34532.1 - 1.1e-07 31.5 4.5 1.1e-07 31.5 4.5 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ34532.1 - 8.7e-07 29.2 8.1 8.7e-07 29.2 8.1 2.2 2 1 0 2 2 2 1 Ring finger domain EF-hand_1 PF00036.32 CBZ34532.1 - 1.1e-06 27.7 0.6 0.00028 20.2 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CBZ34532.1 - 1.6e-06 28.4 0.1 2.3e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair Prok-RING_4 PF14447.6 CBZ34532.1 - 2e-06 27.5 6.8 6.4e-06 25.9 6.9 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 EF-hand_6 PF13405.6 CBZ34532.1 - 3.2e-06 26.6 0.5 0.0024 17.6 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain zf-RING_6 PF14835.6 CBZ34532.1 - 1.9e-05 24.5 2.5 1.9e-05 24.5 2.5 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 CBZ34532.1 - 6.4e-05 23.0 1.8 6.4e-05 23.0 1.8 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C2HC5 PF06221.13 CBZ34532.1 - 0.0022 17.9 1.7 0.0076 16.2 1.7 1.8 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type EF-hand_8 PF13833.6 CBZ34532.1 - 0.0023 17.8 0.2 0.041 13.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair zf-RING_11 PF17123.5 CBZ34532.1 - 0.0076 16.0 5.9 0.014 15.2 3.2 2.3 2 0 0 2 2 2 1 RING-like zinc finger EF-hand_5 PF13202.6 CBZ34532.1 - 0.017 14.6 0.5 3.1 7.5 0.2 2.3 2 0 0 2 2 2 0 EF hand zf-RING_10 PF16685.5 CBZ34532.1 - 0.24 11.5 9.8 0.43 10.8 9.0 1.9 1 1 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 CBZ34532.1 - 4.6 7.4 11.5 80 3.4 11.6 2.5 1 1 0 1 1 1 0 Double zinc ribbon DUF4686 PF15742.5 CBZ34533.1 - 0.0063 15.7 15.5 0.0085 15.3 3.8 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4686) BicD PF09730.9 CBZ34533.1 - 0.027 12.9 15.6 0.3 9.5 7.4 2.0 1 1 1 2 2 2 0 Microtubule-associated protein Bicaudal-D DUF16 PF01519.16 CBZ34533.1 - 0.72 10.4 10.7 1.7 9.1 6.2 2.8 1 1 2 3 3 3 0 Protein of unknown function DUF16 Atg14 PF10186.9 CBZ34533.1 - 1.3 8.0 17.9 2.4 7.1 17.1 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CBZ34533.1 - 4.8 6.4 21.6 10 5.4 21.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF641 PF04859.12 CBZ34533.1 - 5.5 7.3 19.2 1.3 9.3 6.7 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 CBZ34533.1 - 9.2 6.4 8.1 13 6.0 4.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mlh1_C PF16413.5 CBZ34535.1 - 4.1e-31 108.4 0.0 1.5e-10 41.0 0.0 3.5 4 0 0 4 4 4 3 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CBZ34535.1 - 1.6e-23 82.6 0.0 3.1e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Kinesin PF00225.23 CBZ34536.1 - 4.4e-58 196.8 0.0 2.7e-40 138.3 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ34536.1 - 2e-11 44.1 0.0 4.7e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding GIT_CC PF16559.5 CBZ34536.1 - 0.055 13.3 3.2 0.18 11.7 3.2 1.9 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 CBZ34536.1 - 0.12 11.7 7.0 0.33 10.3 7.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vps54_N PF10475.9 CBZ34536.1 - 0.24 10.6 0.2 0.41 9.9 0.2 1.2 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DivIC PF04977.15 CBZ34536.1 - 0.9 9.4 4.3 2.2 8.1 4.3 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF1515 PF07439.11 CBZ34536.1 - 2.5 8.1 5.8 0.44 10.6 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF3509 PF12021.8 CBZ34537.1 - 0.057 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) HpcH_HpaI PF03328.14 CBZ34538.1 - 1.6e-21 76.5 0.0 7.4e-10 38.3 0.0 3.3 1 1 0 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 CBZ34538.1 - 2.4e-13 50.0 0.0 3.7e-07 29.6 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold CbiG_C PF01890.16 CBZ34538.1 - 0.041 14.4 0.3 0.24 12.0 0.0 2.2 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus Cnl2_NKP2 PF09447.10 CBZ34538.1 - 0.092 12.9 0.2 0.9 9.7 0.0 2.3 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Pkinase PF00069.25 CBZ34539.1 - 5.5e-64 216.1 0.0 7e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34539.1 - 9.3e-41 139.8 0.0 1.4e-40 139.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ34539.1 - 7.2e-06 25.0 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ34539.1 - 1.4e-05 24.5 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ34539.1 - 0.0025 17.8 0.0 0.12 12.2 0.1 3.0 1 1 2 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 CBZ34539.1 - 0.0098 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 DZR PF12773.7 CBZ34539.1 - 0.012 15.7 0.6 0.025 14.6 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon NOB1_Zn_bind PF08772.11 CBZ34539.1 - 0.053 13.7 0.4 0.1 12.8 0.4 1.4 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_2 PF13240.6 CBZ34539.1 - 0.095 12.4 3.1 0.26 11.1 3.1 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Kinase-like PF14531.6 CBZ34539.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 CBZ34539.1 - 0.21 10.5 0.0 0.39 9.6 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain zf-NADH-PPase PF09297.11 CBZ34539.1 - 0.29 10.8 9.5 0.56 9.9 3.6 2.6 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ABC_tran PF00005.27 CBZ34540.1 - 4.5e-22 79.0 0.0 8.8e-08 32.8 0.0 4.7 4 0 0 4 4 4 4 ABC transporter ABC_membrane PF00664.23 CBZ34540.1 - 2.1e-19 70.2 7.5 3.4e-11 43.3 8.0 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_16 PF13191.6 CBZ34540.1 - 0.0012 19.2 0.5 1.8 8.9 0.0 3.8 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ34540.1 - 0.078 12.9 0.2 0.76 9.7 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase CNDH2_C PF16858.5 CBZ34540.1 - 0.23 11.3 1.6 3.2 7.6 0.1 2.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Dynamin_N PF00350.23 CBZ34540.1 - 4.7 7.2 6.8 1.1 9.2 2.1 2.3 3 0 0 3 3 3 0 Dynamin family WD40 PF00400.32 CBZ34542.1 - 0.017 16.0 2.6 1e+02 4.0 0.1 6.2 6 0 0 6 6 6 0 WD domain, G-beta repeat Focadhesin PF11229.8 CBZ34542.1 - 0.14 10.4 0.1 0.21 9.8 0.1 1.1 1 0 0 1 1 1 0 Focadhesin START PF01852.19 CBZ34543.1 - 1.9e-05 24.2 0.1 0.34 10.3 0.0 3.3 3 0 0 3 3 3 2 START domain DUF2921 PF11145.8 CBZ34543.1 - 0.2 9.5 0.0 0.28 9.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) WD40 PF00400.32 CBZ34544.1 - 8.4e-09 35.9 2.9 0.0034 18.2 0.1 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat FYDLN_acid PF09538.10 CBZ34544.1 - 0.14 12.8 6.6 0.26 12.0 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TCTP PF00838.17 CBZ34545.1 - 1.1e-44 152.7 1.4 1.2e-44 152.6 1.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein RICH PF05062.12 CBZ34545.1 - 0.039 14.3 0.4 0.068 13.5 0.4 1.4 1 0 0 1 1 1 0 RICH domain DUF273 PF03314.14 CBZ34545.1 - 0.054 13.1 0.8 0.58 9.7 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF273 UPF0262 PF06793.12 CBZ34545.1 - 0.1 12.7 0.2 0.14 12.3 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) TCTP PF00838.17 CBZ34546.1 - 2e-06 28.3 0.3 2.1e-06 28.2 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein ERCC4 PF02732.15 CBZ34547.1 - 9.4e-12 45.4 0.0 2e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 ERCC4 domain SAP PF02037.27 CBZ34547.1 - 4.2e-06 26.4 0.4 1.2e-05 24.9 0.4 1.8 1 0 0 1 1 1 1 SAP domain RecQ_Zn_bind PF16124.5 CBZ34548.1 - 1.2e-15 58.0 0.0 3.3e-15 56.5 0.0 1.9 1 0 0 1 1 1 1 RecQ zinc-binding DEAD PF00270.29 CBZ34548.1 - 9.6e-15 54.8 0.0 5.1e-14 52.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ34548.1 - 9.4e-14 51.7 0.0 3.1e-12 46.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.23 CBZ34548.1 - 6.5e-05 22.8 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 HRDC domain GreA_GreB_N PF03449.15 CBZ34548.1 - 0.03 14.5 3.1 0.076 13.2 3.1 1.6 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal Choline_kin_N PF04428.14 CBZ34548.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Choline kinase N terminus DHR10 PF18595.1 CBZ34548.1 - 0.5 10.4 6.0 1.2 9.2 6.0 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Clat_adaptor_s PF01217.20 CBZ34549.1 - 1.3e-44 151.6 0.9 1.6e-44 151.3 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MRG PF05712.13 CBZ34549.1 - 0.047 13.0 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 MRG LRR_6 PF13516.6 CBZ34551.1 - 0.00029 20.7 0.6 1.9 8.7 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich repeat EF-hand_6 PF13405.6 CBZ34551.1 - 0.025 14.5 0.1 7.5 6.8 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 CBZ34551.1 - 0.13 11.9 1.3 13 5.6 0.1 3.1 3 0 0 3 3 3 0 EF hand RRM_1 PF00076.22 CBZ34552.1 - 1.2e-31 108.4 0.8 2.2e-21 75.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ34552.1 - 4.1e-05 23.5 0.0 0.023 14.7 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 CBZ34552.1 - 0.0022 18.0 0.0 0.0062 16.6 0.0 1.7 1 0 0 1 1 1 1 Limkain b1 RRM_5 PF13893.6 CBZ34552.1 - 0.0026 17.4 0.0 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ34552.1 - 0.0034 17.5 0.0 1.6 8.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 CBZ34552.1 - 0.049 13.9 3.4 4.3 7.5 0.0 3.3 4 1 1 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 CBZ34552.1 - 0.1 12.4 0.0 0.33 10.8 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif PAT1 PF09770.9 CBZ34552.1 - 3.8 5.7 14.2 5.9 5.0 14.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UBA PF00627.31 CBZ34553.1 - 0.00088 19.1 0.5 0.0017 18.2 0.5 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 CBZ34553.1 - 0.0031 17.5 1.0 0.0069 16.4 1.0 1.6 1 1 0 1 1 1 1 Rhomboid family UBA_4 PF14555.6 CBZ34553.1 - 0.046 13.6 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DUF2967 PF11179.8 CBZ34553.1 - 0.88 7.6 4.1 1.2 7.2 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) zf-rbx1 PF12678.7 CBZ34556.1 - 5.4e-21 74.6 13.0 7.3e-21 74.2 13.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ34556.1 - 4.7e-12 45.8 9.4 6.5e-12 45.3 9.2 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CBZ34556.1 - 1.4e-09 38.1 5.4 1.4e-09 38.1 5.4 2.2 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBZ34556.1 - 3.1e-06 26.9 10.9 4.8e-05 23.1 10.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBZ34556.1 - 0.00027 20.8 3.4 0.00027 20.8 3.4 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ34556.1 - 0.00097 18.9 15.6 0.022 14.6 15.6 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBZ34556.1 - 0.002 17.8 13.1 0.45 10.3 13.1 2.4 1 1 0 1 1 1 1 RING-like zinc finger Zn_ribbon_17 PF17120.5 CBZ34556.1 - 0.007 16.0 15.9 0.088 12.4 4.7 2.2 1 1 1 2 2 2 2 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 CBZ34556.1 - 0.11 12.7 10.1 0.26 11.5 10.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 CBZ34556.1 - 0.11 12.5 13.4 0.65 10.1 13.4 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ34556.1 - 0.17 11.8 12.7 1.2 9.2 12.7 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.6 CBZ34556.1 - 0.58 10.3 11.1 1 9.5 11.1 1.4 1 1 0 1 1 1 0 PHD-zinc-finger like domain GST_N_4 PF17172.4 CBZ34557.1 - 2.5e-14 53.8 0.0 6.3e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 CBZ34557.1 - 4.7e-08 33.4 0.0 1.8e-07 31.5 0.0 2.0 1 1 1 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 CBZ34557.1 - 9.7e-08 31.7 0.3 2.6e-07 30.3 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CBZ34557.1 - 0.00012 22.0 0.0 0.00034 20.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PelD_GGDEF PF16963.5 CBZ34557.1 - 0.0074 16.1 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 1 PelD GGDEF domain FAD_binding_2 PF00890.24 CBZ34558.1 - 5.8e-117 391.3 2.4 3.4e-116 388.8 1.1 1.9 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 CBZ34558.1 - 8.5e-42 142.2 1.6 1.3e-41 141.6 1.6 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 CBZ34558.1 - 0.00055 19.3 0.2 0.0012 18.2 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CBZ34558.1 - 0.0012 18.2 0.1 0.15 11.3 0.1 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 CBZ34558.1 - 0.0071 16.0 0.3 0.049 13.2 0.3 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CBZ34558.1 - 0.026 13.2 0.1 0.044 12.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 CBZ34558.1 - 0.05 12.7 3.3 0.11 11.5 2.4 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CBZ34558.1 - 0.13 11.3 2.7 1.7 7.6 0.5 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 CBZ34558.1 - 0.59 9.3 3.2 0.62 9.2 0.3 2.1 2 0 0 2 2 2 0 FAD binding domain NAD_binding_4 PF07993.12 CBZ34559.1 - 1.9e-67 227.1 0.0 2.7e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 CBZ34559.1 - 1.3e-11 44.6 0.2 2.9e-11 43.4 0.2 1.7 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CBZ34559.1 - 9.1e-06 25.3 0.6 0.00013 21.5 0.6 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBZ34559.1 - 0.0011 18.5 0.3 0.96 8.8 0.0 3.0 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CBZ34559.1 - 0.0021 17.2 0.0 0.067 12.3 0.0 2.7 3 0 0 3 3 3 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CBZ34559.1 - 0.027 13.6 0.2 0.76 8.8 0.2 2.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 CBZ34559.1 - 0.06 13.8 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TMF_TATA_bd PF12325.8 CBZ34560.1 - 0.012 15.8 10.6 0.012 15.8 10.6 4.4 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF4515 PF14988.6 CBZ34560.1 - 0.02 14.8 47.0 0.091 12.6 26.9 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4515) DUF2312 PF10073.9 CBZ34560.1 - 0.042 13.5 0.5 0.042 13.5 0.5 3.7 4 1 1 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2312) FlaC_arch PF05377.11 CBZ34560.1 - 0.089 13.2 11.5 0.67 10.4 0.1 4.6 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) BRE1 PF08647.11 CBZ34560.1 - 0.4 10.8 34.0 1.3 9.2 0.3 4.1 3 2 0 3 3 3 0 BRE1 E3 ubiquitin ligase RasGAP_C PF03836.15 CBZ34560.1 - 7.2 6.8 30.8 3.3 7.9 1.1 4.2 2 2 2 4 4 4 0 RasGAP C-terminus Filament PF00038.21 CBZ34560.1 - 9.6 5.7 48.5 0.62 9.6 3.9 3.2 1 1 1 2 2 2 0 Intermediate filament protein SpoU_methylase PF00588.19 CBZ34561.1 - 1.8e-14 54.1 0.1 9.8e-12 45.2 0.0 3.2 2 1 0 2 2 2 1 SpoU rRNA Methylase family Pterin_4a PF01329.19 CBZ34562.1 - 0.023 14.9 0.6 0.48 10.6 0.0 2.8 3 1 0 3 3 3 0 Pterin 4 alpha carbinolamine dehydratase Ssl1 PF04056.14 CBZ34563.1 - 2.3e-18 66.7 0.1 4.4e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Ssl1-like VWA_2 PF13519.6 CBZ34563.1 - 1.6e-08 35.1 0.0 3.9e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Ifi-6-16 PF06140.13 CBZ34563.1 - 2.9 7.8 8.9 1.8 8.5 0.9 2.7 1 1 1 2 2 2 0 Interferon-induced 6-16 family Rubredoxin_2 PF18073.1 CBZ34563.1 - 3.5 7.5 11.1 2.4 8.0 0.6 3.5 3 0 0 3 3 3 0 Rubredoxin metal binding domain DZR PF12773.7 CBZ34563.1 - 6.8 6.8 10.8 20 5.3 4.4 2.7 1 1 1 2 2 2 0 Double zinc ribbon SET PF00856.28 CBZ34564.1 - 1.7e-09 38.3 0.2 3.6e-09 37.2 0.2 1.6 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 CBZ34564.1 - 0.00046 19.9 3.9 0.00052 19.7 0.4 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-tcix PF14952.6 CBZ34564.1 - 0.0057 16.3 1.6 0.0057 16.3 1.6 3.3 4 0 0 4 4 4 1 Putative treble-clef, zinc-finger, Zn-binding TPR_2 PF07719.17 CBZ34564.1 - 0.013 15.6 3.4 0.02 15.0 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2116 PF09889.9 CBZ34564.1 - 8.7 6.4 7.9 33 4.6 8.0 2.0 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Clathrin-link PF09268.10 CBZ34565.1 - 0.16 11.4 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Ribosomal_S21 PF01165.20 CBZ34565.1 - 0.85 9.4 3.9 0.22 11.3 0.2 1.9 2 0 0 2 2 2 0 Ribosomal protein S21 UQ_con PF00179.26 CBZ34566.1 - 1.2e-18 67.2 0.0 1.6e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CBZ34566.1 - 0.00053 19.7 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B WD40 PF00400.32 CBZ34567.1 - 2.4e-25 88.3 17.1 4e-06 27.5 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ34567.1 - 8.5e-22 77.3 1.7 1.6e-07 31.5 0.2 6.0 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBZ34567.1 - 4.5e-06 26.7 0.1 0.31 10.9 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CBZ34567.1 - 0.0018 17.3 0.3 0.67 8.9 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 CBZ34567.1 - 0.066 11.2 1.8 0.78 7.6 0.0 2.5 3 0 0 3 3 3 0 IKI3 family Nbas_N PF15492.6 CBZ34567.1 - 0.071 12.4 0.2 2.6 7.3 0.0 2.6 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 CBZ34567.1 - 0.6 8.7 4.4 9.2 4.8 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 Pkinase PF00069.25 CBZ34568.1 - 2.3e-48 164.9 0.0 3.8e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34568.1 - 3.6e-28 98.6 0.0 8.4e-28 97.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 CBZ34568.1 - 6.4e-07 29.0 1.8 3.3e-05 23.5 0.2 3.6 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CBZ34568.1 - 2.2e-06 27.9 1.5 0.00046 20.5 0.2 2.9 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Kinase-like PF14531.6 CBZ34568.1 - 0.00035 20.0 0.0 0.003 16.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like zf-UBR PF02207.20 CBZ34568.1 - 0.011 15.9 1.8 0.011 15.9 1.8 3.4 3 1 0 3 3 2 0 Putative zinc finger in N-recognin (UBR box) LRR_1 PF00560.33 CBZ34568.1 - 0.043 14.4 1.8 19 6.3 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 CBZ34568.1 - 0.072 13.2 0.0 14 6.0 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat zf-B_box PF00643.24 CBZ34568.1 - 0.095 12.9 24.2 0.5 10.6 8.9 3.1 2 1 0 2 2 2 0 B-box zinc finger C1_2 PF03107.16 CBZ34568.1 - 0.36 11.2 27.8 0.015 15.6 5.7 3.0 3 0 0 3 3 3 0 C1 domain zf-H2C2_5 PF13909.6 CBZ34568.1 - 0.5 10.2 2.6 1.6 8.5 2.6 1.9 1 0 0 1 1 1 0 C2H2-type zinc-finger domain ZZ PF00569.17 CBZ34568.1 - 1.4 8.8 22.1 3.2 7.6 5.9 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type GCV_T PF01571.21 CBZ34569.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Gar1 PF04410.14 CBZ34569.1 - 0.21 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region SET PF00856.28 CBZ34570.1 - 1.6e-09 38.4 0.0 4e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 SET domain CGI-121 PF08617.10 CBZ34571.1 - 9e-07 29.2 0.0 1.6e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 Kinase binding protein CGI-121 Inhibitor_I42 PF09394.10 CBZ34572.1 - 4.7e-19 68.6 0.0 5.7e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Inhibitor_I71 PF12628.7 CBZ34572.1 - 0.0042 16.9 0.3 1.4 8.8 0.0 2.1 1 1 1 2 2 2 2 Falstatin, cysteine peptidase inhibitor CA_like PF10563.9 CBZ34572.1 - 0.083 12.8 0.0 0.083 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative carbonic anhydrase AMP-binding PF00501.28 CBZ34573.1 - 9.4e-14 50.8 2.2 0.00045 18.9 0.9 4.9 3 1 0 3 3 3 3 AMP-binding enzyme DUF5566 PF17721.1 CBZ34573.1 - 0.4 10.9 5.4 2.9 8.1 0.5 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5566) RRM_1 PF00076.22 CBZ34574.1 - 1.8e-16 59.7 0.0 5.2e-16 58.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ34574.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 CBZ34574.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.6 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SPX PF03105.19 CBZ34574.1 - 0.46 10.3 4.9 0.53 10.2 4.9 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 CBZ34574.1 - 0.76 8.4 11.2 0.98 8.0 11.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 CBZ34574.1 - 1.2 9.1 23.2 1.6 8.7 23.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 CBZ34574.1 - 3.5 7.1 7.6 5 6.6 7.6 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2076 PF09849.9 CBZ34574.1 - 4.2 7.3 31.7 5.9 6.9 31.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PAT1 PF09770.9 CBZ34574.1 - 9.3 4.4 18.5 12 4.0 18.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mannitol_dh_C PF08125.13 CBZ34575.1 - 0.052 13.0 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain adh_short PF00106.25 CBZ34576.1 - 4.5e-19 68.7 0.1 8.2e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ34576.1 - 1.3e-10 41.3 0.1 2.6e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ34576.1 - 6.4e-07 29.4 0.2 1.5e-06 28.2 0.2 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ34576.1 - 0.011 15.2 0.3 0.046 13.2 0.1 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 CBZ34576.1 - 0.016 15.6 0.1 0.034 14.6 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 CBZ34577.1 - 1.2e-22 80.4 0.0 9.2e-14 51.3 0.0 3.2 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ34577.1 - 4.9e-11 42.6 0.0 1.2e-07 31.5 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ34577.1 - 3.3e-06 27.1 0.0 3.3e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CBZ34577.1 - 0.024 14.1 0.0 0.059 12.8 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.6 CBZ34577.1 - 0.1 13.0 0.0 0.31 11.5 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding WVELL PF14043.6 CBZ34578.1 - 0.05 13.4 0.3 0.098 12.5 0.3 1.5 1 0 0 1 1 1 0 WVELL protein Abhydrolase_2 PF02230.16 CBZ34579.1 - 5.2e-37 127.8 0.0 6.8e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CBZ34579.1 - 0.00013 21.4 0.3 0.074 12.3 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ34579.1 - 0.0037 17.9 0.2 0.005 17.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBZ34579.1 - 0.0093 15.6 0.3 1.8 8.2 0.0 2.7 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 CBZ34579.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.18 CBZ34579.1 - 0.058 12.9 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family SMG1_N PF17229.2 CBZ34579.1 - 0.089 13.5 0.0 0.29 11.9 0.0 1.8 1 0 0 1 1 1 0 Serine/threonine-protein kinase SMG1 N-terminal Esterase PF00756.20 CBZ34579.1 - 0.17 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PARM PF17061.5 CBZ34580.1 - 0.31 11.1 6.7 0.14 12.3 2.0 2.1 2 0 0 2 2 2 0 PARM DUF2981 PF11200.8 CBZ34581.1 - 1.4 8.6 4.2 2.5 7.8 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) LAP1C PF05609.12 CBZ34581.1 - 4.8 6.2 11.5 7.9 5.4 11.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SPRY PF00622.28 CBZ34582.1 - 0.032 14.4 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 SPRY domain Cyclin PF08613.11 CBZ34583.1 - 2.5e-17 63.7 0.1 4.7e-17 62.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBZ34583.1 - 2e-07 30.8 0.2 4.3e-07 29.7 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CBZ34584.1 - 1.5e-20 74.2 0.0 2.8e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBZ34584.1 - 2.9e-06 27.1 0.0 4.5e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain PFU PF09070.11 CBZ34585.1 - 5.6e-26 91.0 0.2 8.8e-26 90.4 0.2 1.3 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CBZ34585.1 - 6.1e-22 77.5 26.0 5.1e-05 24.0 0.2 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PUL PF08324.11 CBZ34585.1 - 2.8e-07 30.1 1.9 5e-07 29.2 1.9 1.3 1 0 0 1 1 1 1 PUL domain PPTA PF01239.22 CBZ34586.1 - 0.0026 17.4 8.7 0.01 15.5 1.1 3.4 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat DnaJ PF00226.31 CBZ34587.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain DUF4574 PF15141.6 CBZ34588.1 - 0.0048 16.8 0.7 0.016 15.1 0.3 2.1 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 CEP63 PF17045.5 CBZ34588.1 - 0.028 14.3 22.6 0.052 13.4 6.3 2.4 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa UPF0242 PF06785.11 CBZ34588.1 - 0.21 11.7 18.0 0.75 9.9 4.9 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus ADIP PF11559.8 CBZ34588.1 - 0.92 9.6 26.2 0.21 11.6 7.3 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding KLRAQ PF10205.9 CBZ34588.1 - 1.9 8.8 11.8 0.1 12.9 1.7 3.0 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein YabA PF06156.13 CBZ34588.1 - 9.6 6.9 14.6 5.9 7.6 1.0 3.6 3 1 1 4 4 4 0 Initiation control protein YabA Ins134_P3_kin PF05770.11 CBZ34589.1 - 1.3e-06 28.1 0.0 0.0081 15.7 0.1 3.4 3 0 0 3 3 3 3 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Cnn_1N PF07989.11 CBZ34592.1 - 0.0033 17.6 4.7 0.0033 17.6 4.7 4.1 2 2 3 5 5 5 1 Centrosomin N-terminal motif 1 Utp12 PF04003.12 CBZ34592.1 - 6.8 7.1 8.2 1.8 8.9 2.8 2.7 2 0 0 2 2 2 0 Dip2/Utp12 Family DUF1515 PF07439.11 CBZ34593.1 - 0.17 11.9 0.5 0.38 10.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) TetR_C_14 PF17754.1 CBZ34593.1 - 0.65 9.9 6.4 0.31 11.0 0.9 2.7 2 0 0 2 2 2 0 MftR C-terminal domain TruB_C PF09142.11 CBZ34594.1 - 0.14 12.0 0.1 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal STOP PF05217.12 CBZ34594.1 - 0.55 10.6 12.8 0.26 11.6 9.6 2.3 2 1 0 2 2 2 0 STOP protein Pdase_M17_N2 PF18295.1 CBZ34595.1 - 2.2 8.6 6.7 0.73 10.1 3.5 1.8 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 PCIF1_WW PF12237.8 CBZ34596.1 - 2.2e-12 46.9 0.0 7.4e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain POTRA PF07244.15 CBZ34596.1 - 0.074 13.6 0.0 0.76 10.4 0.0 2.5 3 0 0 3 3 3 0 Surface antigen variable number repeat HTH_25 PF13413.6 CBZ34596.1 - 0.12 12.3 0.2 4.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain PI3_PI4_kinase PF00454.27 CBZ34597.1 - 1.6e-42 146.0 0.0 7.3e-28 98.0 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CBZ34597.1 - 3.2e-22 78.8 0.0 6.4e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 CBZ34597.1 - 0.00023 21.1 0.0 0.00039 20.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 CBZ34597.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) TFCD_C PF12612.8 CBZ34598.1 - 9.5e-32 110.4 0.1 4.4e-31 108.2 0.1 2.3 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 CBZ34598.1 - 6.3e-10 39.3 17.6 0.0017 18.7 0.6 7.3 6 1 0 6 6 6 4 HEAT repeats Cnd1 PF12717.7 CBZ34598.1 - 4.3e-06 26.9 0.2 0.14 12.2 0.0 4.5 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBZ34598.1 - 0.04 14.2 35.1 0.49 10.8 0.0 11.2 12 1 1 13 13 13 0 HEAT repeat adh_short_C2 PF13561.6 CBZ34599.1 - 1.5e-43 149.1 0.3 2e-43 148.6 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBZ34599.1 - 1.8e-42 145.1 1.4 2.3e-42 144.7 1.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBZ34599.1 - 1.2e-10 41.6 3.6 1e-09 38.6 3.6 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ34599.1 - 6.6e-06 25.8 0.4 2.1e-05 24.1 0.4 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 CBZ34599.1 - 3.5e-05 23.2 0.8 6.3e-05 22.4 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 CBZ34599.1 - 0.012 15.5 2.1 0.014 15.3 1.6 1.5 1 1 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 CBZ34599.1 - 0.048 13.6 0.5 0.083 12.8 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2235 PF09994.9 CBZ34599.1 - 0.055 12.8 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sacchrp_dh_NADP PF03435.18 CBZ34599.1 - 0.065 13.5 0.8 0.095 13.0 0.8 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 CBZ34599.1 - 0.082 12.3 0.4 0.16 11.3 0.1 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 CBZ34599.1 - 0.086 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NmrA PF05368.13 CBZ34599.1 - 0.17 11.4 0.9 0.3 10.6 0.9 1.3 1 0 0 1 1 1 0 NmrA-like family Shikimate_DH PF01488.20 CBZ34599.1 - 0.22 11.6 1.2 0.31 11.1 0.5 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase BolA PF01722.18 CBZ34600.1 - 9.6e-15 54.6 0.0 1.1e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein Ribosomal_L26 PF16906.5 CBZ34602.1 - 5.5e-35 119.7 0.7 6.3e-35 119.5 0.7 1.0 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CBZ34602.1 - 1.5e-06 27.9 0.8 4e-06 26.6 0.8 1.8 1 1 0 1 1 1 1 KOW motif Transketolase_N PF00456.21 CBZ34603.1 - 3.9e-139 463.3 0.1 5.2e-139 462.9 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CBZ34603.1 - 9.5e-43 145.9 0.0 1.6e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBZ34603.1 - 4e-09 36.4 0.1 8.7e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 CBZ34603.1 - 0.00014 21.6 0.2 0.00077 19.3 0.1 2.3 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 CBZ34603.1 - 0.0023 17.2 0.0 0.0045 16.2 0.0 1.4 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Terpene_synth PF01397.21 CBZ34603.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Ribosomal_S8e PF01201.22 CBZ34604.1 - 1.6e-46 157.9 1.8 1.9e-46 157.7 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_S8e PF01201.22 CBZ34605.1 - 2.4e-18 66.6 1.4 2.6e-18 66.5 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Kelch_3 PF13415.6 CBZ34606.1 - 7.8e-40 134.4 4.9 2.4e-09 37.2 0.0 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ34606.1 - 1.4e-35 120.6 20.9 3.8e-08 32.8 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CBZ34606.1 - 2.9e-35 120.0 17.8 1e-06 28.7 0.1 6.9 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ34606.1 - 2.6e-31 107.1 15.6 2e-07 30.8 0.5 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CBZ34606.1 - 7.5e-29 99.0 10.7 2.4e-07 30.8 0.0 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CBZ34606.1 - 5.5e-26 89.5 16.1 1.9e-06 27.6 0.4 6.6 6 1 0 6 6 6 6 Kelch motif TPR_19 PF14559.6 CBZ34607.1 - 0.04 14.4 0.4 0.04 14.4 0.4 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ34607.1 - 0.42 11.3 8.0 1.5 9.5 8.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4129 PF13559.6 CBZ34607.1 - 6 7.2 11.3 2.5e+02 2.0 11.3 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4129) HMG_CoA_synt_N PF01154.17 CBZ34608.1 - 6.5e-12 45.7 0.2 1.2e-11 44.8 0.2 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 CBZ34608.1 - 1.2e-06 28.4 0.1 0.00033 20.4 0.0 2.4 2 0 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III PF08545.10 CBZ34608.1 - 0.00048 19.9 0.5 0.0012 18.7 0.2 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III UQ_con PF00179.26 CBZ34610.1 - 1.4e-44 151.2 0.1 1.5e-44 151.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CBZ34610.1 - 0.00087 19.1 0.3 0.0015 18.4 0.3 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 CBZ34610.1 - 0.00089 19.5 0.2 0.0012 19.1 0.2 1.4 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CBZ34610.1 - 0.0094 15.7 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UQ_con PF00179.26 CBZ34611.1 - 2e-07 30.7 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBZ34611.1 - 0.049 13.9 0.0 0.068 13.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain CBM_5_12_2 PF14600.6 CBZ34611.1 - 0.07 13.1 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 Cellulose-binding domain DUF1917 PF08939.10 CBZ34612.1 - 0.005 16.8 1.1 0.0055 16.6 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) GDPD PF03009.17 CBZ34613.1 - 9.6e-21 74.7 0.0 1.4e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Vps54_N PF10475.9 CBZ34614.1 - 3.8e-13 49.4 1.5 7.7e-13 48.4 1.5 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 CBZ34614.1 - 1.2e-11 44.9 2.1 1.3e-11 44.7 1.0 1.6 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 CBZ34614.1 - 0.0016 18.4 0.6 0.0039 17.1 0.6 1.6 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain KELK PF15796.5 CBZ34615.1 - 0.006 17.0 8.9 0.006 17.0 8.9 19.1 7 6 15 23 23 23 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase WD40_alt PF14077.6 CBZ34615.1 - 0.97 9.3 3.2 1.8 8.5 0.8 2.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif Asparaginase_C PF17763.1 CBZ34616.1 - 0.017 15.3 1.7 4.6 7.5 0.3 3.0 2 1 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain PPR_3 PF13812.6 CBZ34617.1 - 1.6e-12 47.3 0.0 2.5e-05 24.2 0.0 3.0 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ34617.1 - 3.4e-06 26.6 0.1 0.015 14.7 0.0 2.0 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 CBZ34617.1 - 4e-06 26.9 0.0 0.0032 17.6 0.0 2.8 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.20 CBZ34617.1 - 0.014 15.6 0.0 12 6.4 0.0 3.5 4 0 0 4 4 4 0 PPR repeat AAA_16 PF13191.6 CBZ34618.1 - 0.018 15.4 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 CBZ34618.1 - 0.043 13.8 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CBZ34618.1 - 0.12 12.8 0.0 0.34 11.3 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CBZ34618.1 - 0.14 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain UPF0014 PF03649.13 CBZ34619.1 - 0.24 10.7 5.2 0.4 10.0 5.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0014) DUF2070 PF09843.9 CBZ34619.1 - 0.77 8.0 2.7 0.84 7.9 2.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF1294 PF06961.13 CBZ34619.1 - 1.6 9.0 3.9 2.5 8.4 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1294) DUF5345 PF17280.2 CBZ34619.1 - 7.6 6.6 8.1 1 9.4 2.0 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5345) Cob_adeno_trans PF01923.18 CBZ34620.1 - 8.5e-52 175.6 0.4 1.3e-51 175.1 0.4 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF5522 PF17653.1 CBZ34620.1 - 8.5e-21 73.7 1.1 8.5e-21 73.7 1.1 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5522) FA_desaturase PF00487.24 CBZ34621.1 - 2.9e-18 66.6 19.4 2.9e-18 66.6 19.4 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBZ34621.1 - 5e-08 33.0 0.4 6e-07 29.5 0.0 2.9 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DUF2269 PF10027.9 CBZ34621.1 - 0.031 14.3 1.2 0.068 13.2 1.2 1.5 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) TssN PF17555.2 CBZ34621.1 - 0.06 12.7 0.1 0.06 12.7 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN WD40 PF00400.32 CBZ34622.1 - 5.3e-54 179.0 31.4 4.7e-08 33.6 0.0 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ34622.1 - 3.1e-21 75.4 4.5 0.0012 19.1 0.0 6.4 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CBZ34622.1 - 1.9e-12 47.5 0.1 3.2e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 CBZ34622.1 - 1.6e-08 33.9 0.3 0.048 12.6 0.0 4.5 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CBZ34622.1 - 5.2e-07 29.7 0.1 0.052 13.4 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBZ34622.1 - 2.7e-06 27.0 0.0 0.56 9.5 0.0 3.3 2 1 1 3 3 3 3 WD40-like domain PD40 PF07676.12 CBZ34622.1 - 2.6e-05 24.0 3.1 1.9 8.5 0.1 5.0 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 CBZ34622.1 - 0.00036 19.9 0.1 0.27 10.5 0.0 3.5 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal DHHC PF01529.20 CBZ34623.1 - 1.8e-14 54.0 11.0 1.8e-14 54.0 11.0 3.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase DEAD_2 PF06733.15 CBZ34624.1 - 1.7e-39 135.3 0.0 4.4e-39 133.9 0.0 1.7 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CBZ34624.1 - 2.9e-39 135.0 0.0 6e-39 133.9 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 CBZ34624.1 - 8.8e-35 120.1 1.0 4e-29 101.7 0.2 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain DEAD PF00270.29 CBZ34624.1 - 0.00013 21.8 0.4 0.0096 15.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CBZ34624.1 - 0.00028 20.9 0.8 0.0026 17.8 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBZ34624.1 - 0.011 16.1 0.0 0.033 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Glyco_transf_21 PF13506.6 CBZ34624.1 - 0.022 14.3 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Flavi_DEAD PF07652.14 CBZ34624.1 - 0.022 14.7 0.7 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.6 CBZ34624.1 - 0.026 14.8 1.1 0.32 11.3 0.0 3.2 3 1 0 3 3 3 0 AAA domain SAPIS-gp6 PF16722.5 CBZ34624.1 - 0.18 12.2 0.5 0.41 11.1 0.5 1.5 1 0 0 1 1 1 0 Pathogenicity island protein gp6 in Staphylococcus Cullin PF00888.22 CBZ34625.1 - 5.1e-79 266.5 0.0 6.7e-79 266.1 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBZ34625.1 - 7.6e-23 80.3 0.2 2e-22 79.0 0.2 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Succ_CoA_lig PF13607.6 CBZ34626.1 - 0.029 14.2 0.2 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain SlyX PF04102.12 CBZ34626.1 - 0.16 12.6 0.1 1.8 9.3 0.0 2.2 2 0 0 2 2 2 0 SlyX Vac_Fusion PF02346.16 CBZ34626.1 - 0.16 11.6 0.1 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 HSBP1 PF06825.12 CBZ34626.1 - 0.2 11.5 0.2 4.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Heat shock factor binding protein 1 ABC_tran_CTD PF16326.5 CBZ34627.1 - 0.014 15.6 0.7 0.014 15.6 0.7 3.6 3 1 0 3 3 3 0 ABC transporter C-terminal domain DUF641 PF04859.12 CBZ34627.1 - 0.021 15.1 10.5 0.57 10.5 4.8 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HIP1_clath_bdg PF16515.5 CBZ34627.1 - 0.028 15.0 5.8 0.028 15.0 5.8 2.4 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LRRFIP PF09738.9 CBZ34627.1 - 0.1 12.1 14.9 4.9 6.5 14.9 2.1 1 1 0 1 1 1 0 LRRFIP family DUF4201 PF13870.6 CBZ34627.1 - 0.11 12.2 15.2 0.31 10.8 2.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Lectin_N PF03954.14 CBZ34627.1 - 0.21 11.3 3.8 0.58 9.9 0.8 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain FlxA PF14282.6 CBZ34627.1 - 0.22 11.5 9.7 0.27 11.2 0.8 2.3 2 0 0 2 2 2 0 FlxA-like protein Tup_N PF08581.10 CBZ34627.1 - 0.25 11.7 0.2 0.25 11.7 0.2 3.1 2 1 1 3 3 3 0 Tup N-terminal Snapin_Pallidin PF14712.6 CBZ34627.1 - 0.44 11.0 13.5 2.6 8.5 1.1 3.2 1 1 2 3 3 3 0 Snapin/Pallidin Cir_N PF10197.9 CBZ34627.1 - 0.77 10.0 0.1 0.77 10.0 0.1 3.4 3 2 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR ADIP PF11559.8 CBZ34627.1 - 0.99 9.5 13.7 3.6 7.7 11.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.6 CBZ34627.1 - 1.1 9.6 20.1 0.7 10.3 4.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Exonuc_VII_L PF02601.15 CBZ34627.1 - 1.5 8.3 6.4 1.9 8.0 6.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 CBZ34627.1 - 1.5 8.8 5.8 1 9.4 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CBZ34627.1 - 1.7 7.9 9.4 2.1 7.6 9.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 CBZ34627.1 - 1.8 8.6 14.8 6.8 6.7 14.8 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 CBZ34627.1 - 1.9 9.0 4.9 1.8 9.1 0.2 3.0 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) Enkurin PF13864.6 CBZ34627.1 - 2.1 8.8 10.2 11 6.5 10.2 2.4 1 1 0 1 1 1 0 Calmodulin-binding DivIC PF04977.15 CBZ34627.1 - 3.7 7.4 18.7 1.5 8.6 2.7 3.7 1 1 3 4 4 4 0 Septum formation initiator APG6_N PF17675.1 CBZ34627.1 - 4.1 7.9 21.5 1.3 9.6 4.6 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region GrpE PF01025.19 CBZ34627.1 - 4.9 6.8 13.2 62 3.2 13.2 2.2 1 1 0 1 1 1 0 GrpE TPR_MLP1_2 PF07926.12 CBZ34627.1 - 6.4 6.9 19.1 0.2 11.7 6.8 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMPIT PF07851.13 CBZ34627.1 - 7.2 5.8 9.7 9.3 5.4 3.6 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF724 PF05266.14 CBZ34627.1 - 8.2 6.2 11.2 16 5.3 10.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Pkinase PF00069.25 CBZ34628.1 - 1.6e-60 204.7 0.0 1.9e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34628.1 - 4.4e-39 134.3 0.0 5.7e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ34628.1 - 0.001 18.5 0.0 0.003 16.9 0.0 1.7 1 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CBZ34628.1 - 0.0042 16.7 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBZ34628.1 - 0.018 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Methyltransf_33 PF10017.9 CBZ34628.1 - 0.065 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent SpoU_methylase PF00588.19 CBZ34630.1 - 5.6e-14 52.5 0.0 1.7e-07 31.5 0.0 2.5 2 1 0 2 2 2 2 SpoU rRNA Methylase family Glycos_transf_2 PF00535.26 CBZ34631.1 - 1.3e-07 31.6 0.1 3.1e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 FR47 PF08445.10 CBZ34632.1 - 9.5e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CBZ34632.1 - 1.5e-06 28.2 0.1 2.1e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ34632.1 - 3.4e-06 27.3 0.0 4.6e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBZ34632.1 - 0.00049 20.5 0.1 0.0011 19.3 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2431 PF10354.9 CBZ34633.1 - 6.8e-24 85.0 0.0 1.1e-23 84.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2 PF00096.26 CBZ34633.1 - 5e-05 23.5 19.6 0.081 13.4 0.1 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CBZ34633.1 - 0.00013 22.2 1.1 0.27 11.5 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CBZ34633.1 - 0.013 16.3 17.8 0.49 11.4 0.1 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 CBZ34633.1 - 0.026 14.9 0.1 0.026 14.9 0.1 3.9 3 2 0 3 3 3 0 Zinc-finger of C2H2 type YabA PF06156.13 CBZ34634.1 - 0.061 14.0 0.2 0.061 14.0 0.2 4.2 3 1 1 4 4 4 0 Initiation control protein YabA TSC22 PF01166.18 CBZ34634.1 - 0.69 10.3 4.9 0.85 10.0 0.3 3.3 2 1 1 3 3 3 0 TSC-22/dip/bun family CEP44 PF15007.6 CBZ34635.1 - 0.00029 21.0 0.0 0.00038 20.6 0.0 1.1 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 Got1 PF04178.12 CBZ34636.1 - 6.6e-27 94.2 17.2 8.4e-27 93.8 17.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family AzlD PF05437.12 CBZ34636.1 - 0.13 12.5 6.3 0.58 10.4 6.8 1.8 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF3270 PF11674.8 CBZ34636.1 - 1 9.6 5.8 0.31 11.2 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) DUF2070 PF09843.9 CBZ34636.1 - 2.1 6.5 8.0 2.5 6.3 8.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RRM_1 PF00076.22 CBZ34638.1 - 2.9e-65 216.0 0.4 1.3e-18 66.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CBZ34638.1 - 6.3e-19 67.9 0.3 1.2e-18 67.1 0.3 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 CBZ34638.1 - 1.5e-07 31.2 0.1 0.00089 19.1 0.0 4.1 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_7 PF16367.5 CBZ34638.1 - 9.8e-06 25.6 0.0 0.19 11.9 0.0 4.6 4 2 0 4 4 4 2 RNA recognition motif OB_RNB PF08206.11 CBZ34638.1 - 0.47 10.2 1.3 6.4 6.5 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain RPAP1_N PF08621.10 CBZ34639.1 - 0.03 14.1 2.6 1.4 8.7 0.2 2.2 2 0 0 2 2 2 0 RPAP1-like, N-terminal Ketoacyl-synt_C PF02801.22 CBZ34639.1 - 0.11 12.5 0.3 0.38 10.8 0.3 2.0 1 1 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain RAMP4 PF06624.12 CBZ34640.1 - 0.0012 18.8 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 CrgA PF06781.12 CBZ34640.1 - 0.0079 16.2 0.3 0.0081 16.2 0.3 1.1 1 0 0 1 1 1 1 Cell division protein CrgA DUF364 PF04016.12 CBZ34640.1 - 0.06 12.9 0.0 0.069 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative heavy-metal chelation Kei1 PF08552.11 CBZ34640.1 - 0.1 12.5 0.0 0.12 12.2 0.0 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1345 PF07077.11 CBZ34640.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) ETF PF01012.21 CBZ34642.1 - 1.6e-42 145.5 2.3 2.1e-42 145.1 2.3 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PIG-L PF02585.17 CBZ34642.1 - 0.013 16.1 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase Y_Y_Y PF07495.13 CBZ34642.1 - 0.2 11.6 0.3 1.6 8.8 0.1 2.1 2 0 0 2 2 2 0 Y_Y_Y domain GTP_EFTU PF00009.27 CBZ34643.1 - 7.6e-50 169.1 0.2 1.2e-49 168.5 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CBZ34643.1 - 6e-14 51.8 0.0 1.4e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus Septin PF00735.18 CBZ34643.1 - 1.4e-05 24.5 0.1 2.3e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CBZ34643.1 - 1.9e-05 24.7 0.1 4.2e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CBZ34643.1 - 0.0028 18.0 0.0 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CBZ34643.1 - 0.0095 16.0 0.6 0.05 13.7 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II RNA_pol_Rpb6 PF01192.22 CBZ34644.1 - 3e-08 33.5 0.0 4.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 GIT_CC PF16559.5 CBZ34646.1 - 0.016 15.1 0.2 0.049 13.5 0.2 1.8 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 CBZ34646.1 - 0.13 12.7 0.1 0.34 11.3 0.1 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.11 CBZ34646.1 - 0.32 11.1 0.3 0.32 11.1 0.3 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) TPR_MLP1_2 PF07926.12 CBZ34646.1 - 0.33 11.0 12.0 0.082 13.0 6.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 CBZ34646.1 - 0.34 11.3 7.8 0.43 11.0 0.2 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF724 PF05266.14 CBZ34646.1 - 0.59 9.9 4.8 0.38 10.5 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ZapB PF06005.12 CBZ34646.1 - 4.9 7.7 8.5 3 8.3 0.1 3.0 2 1 1 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 CBZ34646.1 - 9.4 6.1 8.2 1.2 8.9 0.3 2.7 2 1 0 2 2 2 0 Septum formation initiator Lactamase_B_6 PF16661.5 CBZ34647.1 - 2.1e-18 66.5 0.0 3.3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CBZ34647.1 - 5.2e-15 56.0 0.5 5.2e-15 56.0 0.5 2.5 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Lactamase_B_2 PF12706.7 CBZ34647.1 - 0.00012 21.7 0.0 0.00033 20.2 0.0 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CBZ34647.1 - 0.012 15.7 0.3 0.023 14.7 0.3 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF3245 PF11595.8 CBZ34647.1 - 0.061 13.8 0.1 0.15 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Beta-Casp PF10996.8 CBZ34647.1 - 0.07 13.4 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Beta-Casp domain Tryp_alpha_amyl PF00234.22 CBZ34648.1 - 0.51 10.8 4.0 0.36 11.3 0.6 2.4 2 0 0 2 2 2 0 Protease inhibitor/seed storage/LTP family Peptidase_C12 PF01088.21 CBZ34649.1 - 1.7e-54 184.8 0.0 1.9e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 WD40_3 PF15911.5 CBZ34650.1 - 1.3e-14 53.9 0.0 2.8e-13 49.7 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat Clathrin PF00637.20 CBZ34650.1 - 3e-07 30.4 7.1 0.00047 20.0 0.4 4.6 4 0 0 4 4 4 2 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 CBZ34650.1 - 0.00029 21.1 0.0 0.33 11.3 0.0 4.2 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_19 PF14559.6 CBZ34650.1 - 0.0033 17.9 9.8 0.044 14.3 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat zf-ribbon_3 PF13248.6 CBZ34650.1 - 0.053 13.0 5.5 2.2 7.8 2.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain GGA_N-GAT PF18308.1 CBZ34650.1 - 0.15 11.7 0.2 0.54 9.9 0.0 1.9 2 0 0 2 2 2 0 GGA N-GAT domain TPR_7 PF13176.6 CBZ34650.1 - 0.2 11.8 10.9 2.2 8.5 0.4 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ34650.1 - 3 8.9 16.9 30 5.8 0.2 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat Mito_carr PF00153.27 CBZ34651.1 - 2e-60 200.7 0.3 5e-20 71.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CBZ34651.1 - 0.16 11.1 0.3 11 5.0 0.0 3.1 3 1 0 3 3 3 0 Gammaproteobacterial serine protease SyrA PF11089.8 CBZ34652.1 - 0.046 13.8 1.8 0.081 13.0 1.8 1.3 1 0 0 1 1 1 0 Exopolysaccharide production repressor Spt5_N PF11942.8 CBZ34652.1 - 0.31 12.1 7.1 0.43 11.6 0.1 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DSPc PF00782.20 CBZ34653.1 - 1.3e-15 57.3 0.1 2.1e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 CBZ34653.1 - 0.00031 20.4 0.0 0.00049 19.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CBZ34653.1 - 0.0053 16.9 0.0 0.0098 16.0 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CBZ34653.1 - 0.0075 16.3 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBZ34653.1 - 0.02 14.5 0.2 0.027 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF442 PF04273.13 CBZ34653.1 - 0.023 14.8 0.1 0.045 13.8 0.1 1.5 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Bud13 PF09736.9 CBZ34654.1 - 4.1e-07 30.5 0.0 7.7e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor of RES complex ATG16 PF08614.11 CBZ34655.1 - 0.0063 16.8 7.6 0.0063 16.8 7.6 3.4 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) AAA_33 PF13671.6 CBZ34655.1 - 0.1 12.8 7.8 0.13 12.4 0.0 3.4 2 1 0 2 2 2 0 AAA domain KxDL PF10241.9 CBZ34655.1 - 0.11 12.8 2.9 1.4 9.2 0.2 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein TMF_DNA_bd PF12329.8 CBZ34655.1 - 1.1 9.3 6.3 1.3 9.1 0.3 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Lectin_N PF03954.14 CBZ34655.1 - 2.1 8.1 7.8 1.6 8.5 0.2 3.3 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain SlyX PF04102.12 CBZ34655.1 - 3.6 8.3 17.3 1.4 9.6 2.3 3.6 3 0 0 3 3 3 0 SlyX Tli4_N PF18443.1 CBZ34655.1 - 8.3 6.8 7.1 0.56 10.6 1.0 2.1 2 1 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain Dynein_light PF01221.18 CBZ34656.1 - 1.6e-34 118.0 0.1 1.8e-34 117.9 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 YabA PF06156.13 CBZ34657.1 - 7.8 7.2 39.6 0.027 15.1 2.6 7.2 5 2 2 7 7 7 0 Initiation control protein YabA HALZ PF02183.18 CBZ34657.1 - 8.3 6.7 22.5 0.49 10.6 0.6 6.1 6 0 0 6 6 6 0 Homeobox associated leucine zipper V_ATPase_I PF01496.19 CBZ34658.1 - 2.5 5.9 9.7 0.3 8.9 4.1 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family CENP-F_leu_zip PF10473.9 CBZ34658.1 - 6.2 6.8 24.9 0.12 12.3 14.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tho2 PF11262.8 CBZ34658.1 - 6.5 5.9 6.7 1 8.5 2.6 1.6 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 RRM_1 PF00076.22 CBZ34659.1 - 2.5e-05 24.0 1.0 0.0014 18.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Diphthami_syn_2 PF01902.17 CBZ34660.1 - 9e-30 103.8 0.0 2.5e-24 86.0 0.0 2.8 2 1 0 2 2 2 2 Diphthamide synthase FTR PF01913.18 CBZ34661.1 - 0.022 14.7 0.3 0.024 14.6 0.3 1.1 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase DUF3530 PF12048.8 CBZ34661.1 - 0.031 13.7 0.6 0.033 13.6 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) BRCT_2 PF16589.5 CBZ34662.1 - 1.4e-05 25.4 0.0 0.3 11.5 0.0 2.6 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain TMEM171 PF15471.6 CBZ34662.1 - 0.012 14.6 2.0 0.025 13.6 2.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 LIG3_BRCT PF16759.5 CBZ34662.1 - 0.026 14.8 0.0 12 6.3 0.0 2.4 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain B9-C2 PF07162.11 CBZ34663.1 - 2.6e-43 148.1 0.2 2.9e-43 148.0 0.2 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein SPRY PF00622.28 CBZ34664.1 - 1.9e-05 24.8 0.0 3.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 SPRY domain baeRF_family12 PF18856.1 CBZ34664.1 - 0.31 11.6 4.2 0.17 12.5 0.6 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 DUF1308 PF07000.11 CBZ34666.1 - 2.8e-21 76.1 0.0 3.6e-20 72.6 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1308) zf_C2H2_13 PF18508.1 CBZ34667.1 - 0.14 11.8 0.2 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 Zinc finger domain Fcf2 PF08698.11 CBZ34668.1 - 1.1e-07 32.2 6.4 4.4e-07 30.2 6.4 2.0 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing TMEM51 PF15345.6 CBZ34668.1 - 8.9 6.1 7.3 16 5.2 7.3 1.4 1 1 0 1 1 1 0 Transmembrane protein 51 DNA_pol_P_Exo PF18049.1 CBZ34669.1 - 0.016 14.6 0.9 0.033 13.6 0.9 1.5 1 0 0 1 1 1 0 DNA polymerase nu pseudo-exo Phage_lysozyme PF00959.19 CBZ34669.1 - 1.5 9.3 3.7 14 6.2 3.7 2.5 1 1 0 1 1 1 0 Phage lysozyme SUI1 PF01253.22 CBZ34672.1 - 4.3e-18 65.6 0.0 8.3e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 BRX_N PF13713.6 CBZ34673.1 - 0.025 14.3 0.1 0.8 9.5 0.0 2.7 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain Noelin-1 PF12308.8 CBZ34673.1 - 4.2 7.4 26.6 0.37 10.8 1.0 6.6 4 2 2 6 6 6 0 Neurogenesis glycoprotein Baculo_PEP_C PF04513.12 CBZ34673.1 - 4.4 7.4 42.9 0.37 10.8 11.0 6.8 3 1 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.32 CBZ34674.1 - 6.8e-36 121.7 21.6 3.1e-08 34.1 0.8 8.8 9 0 0 9 9 9 6 WD domain, G-beta repeat Utp13 PF08625.11 CBZ34674.1 - 2.5e-34 118.2 1.4 4.2e-34 117.5 1.4 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 CBZ34674.1 - 4.7e-16 58.9 6.0 1.7e-05 25.1 0.1 6.4 5 2 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ34674.1 - 1.7e-06 27.2 4.5 0.24 10.3 0.1 5.4 3 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CBZ34674.1 - 2.1e-05 24.0 0.1 1.7 7.9 0.0 4.4 4 1 1 5 5 5 2 WD40-like domain MMS1_N PF10433.9 CBZ34674.1 - 0.0036 16.0 0.1 0.079 11.6 0.0 2.9 4 0 0 4 4 4 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nup160 PF11715.8 CBZ34674.1 - 0.036 12.7 8.0 0.89 8.1 0.2 4.3 3 2 2 5 5 5 0 Nucleoporin Nup120/160 Utp12 PF04003.12 CBZ34674.1 - 0.041 14.2 0.9 0.084 13.2 0.9 1.6 1 0 0 1 1 1 0 Dip2/Utp12 Family UTP15_C PF09384.10 CBZ34674.1 - 0.056 13.1 2.1 0.18 11.5 2.1 1.8 1 1 0 1 1 1 0 UTP15 C terminal TFIIB PF00382.19 CBZ34675.1 - 2.7e-23 81.8 0.1 1.5e-11 44.2 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CBZ34675.1 - 0.0097 15.4 0.1 0.024 14.2 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding MMR_HSR1 PF01926.23 CBZ34676.1 - 4.1e-13 49.4 0.0 6.7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ34676.1 - 1.4e-07 31.1 0.0 6.8e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ34676.1 - 2.3e-05 24.4 0.0 0.0001 22.3 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 CBZ34676.1 - 0.0025 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CBZ34676.1 - 0.0053 16.3 0.0 0.31 10.6 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CBZ34676.1 - 0.0063 16.6 0.5 0.59 10.2 0.1 2.4 1 1 1 2 2 2 1 Dynamin family SRPRB PF09439.10 CBZ34676.1 - 0.017 14.5 0.0 0.028 13.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit UMP1 PF05348.11 CBZ34677.1 - 0.012 15.8 0.1 0.021 15.1 0.1 1.4 1 0 0 1 1 1 0 Proteasome maturation factor UMP1 Cyt_bd_oxida_II PF02322.15 CBZ34677.1 - 0.082 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Kringle PF00051.18 CBZ34678.1 - 8.7e-09 35.6 0.0 1.9e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Kringle domain CHB_HEX_C_1 PF13290.6 CBZ34678.1 - 0.014 15.3 2.7 0.057 13.4 0.0 3.2 3 1 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.6 CBZ34678.1 - 0.11 12.6 0.0 0.41 10.8 0.0 2.0 1 0 0 1 1 1 0 Fn3 associated Myosin_head PF00063.21 CBZ34679.1 - 0.0046 15.2 0.0 0.0074 14.6 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Tryp_alpha_amyl PF00234.22 CBZ34679.1 - 3.2 8.3 6.2 14 6.1 6.2 2.2 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family CnrY PF17524.2 CBZ34680.1 - 0.038 14.2 0.6 0.042 14.1 0.6 1.0 1 0 0 1 1 1 0 Anti-sigma factor CnrY Vma12 PF11712.8 CBZ34680.1 - 0.14 12.2 0.2 0.16 12.1 0.2 1.0 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RRM_1 PF00076.22 CBZ34681.1 - 6.3e-22 77.2 0.0 8.4e-22 76.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ34681.1 - 8.5e-05 22.1 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ34681.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CBZ34681.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 CBZ34683.1 - 1.2e-18 66.7 0.8 2e-18 65.9 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ34683.1 - 0.0052 16.4 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_membrane PF00664.23 CBZ34684.1 - 3.6e-53 181.0 2.3 5e-53 180.5 2.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ34684.1 - 7.2e-33 114.0 0.0 1.3e-32 113.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBZ34684.1 - 2.5e-05 23.8 0.0 0.038 13.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBZ34684.1 - 0.00012 22.5 0.7 0.0024 18.3 0.7 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CBZ34684.1 - 0.0052 16.8 0.0 0.22 11.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CBZ34684.1 - 0.0058 17.1 0.1 0.085 13.3 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 CBZ34684.1 - 0.006 16.4 0.0 0.074 12.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ABC_ATPase PF09818.9 CBZ34684.1 - 0.0083 15.0 0.1 0.015 14.1 0.1 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 CBZ34684.1 - 0.01 16.1 0.4 0.31 11.3 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.6 CBZ34684.1 - 0.023 14.4 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBZ34684.1 - 0.041 13.8 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Zeta_toxin PF06414.12 CBZ34684.1 - 0.044 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_15 PF13175.6 CBZ34684.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 CBZ34684.1 - 0.13 12.4 0.1 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CBZ34684.1 - 0.16 12.0 0.2 0.44 10.6 0.1 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain LSM14 PF12701.7 CBZ34685.1 - 2.2e-27 95.0 0.1 3.3e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 CBZ34685.1 - 5.5e-06 26.4 0.1 1.1e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 CBZ34685.1 - 0.0022 18.8 18.5 0.12 13.3 3.2 2.8 2 1 1 3 3 3 2 FDF domain DUF5578 PF17741.1 CBZ34686.1 - 6.1e-19 68.5 0.2 2.6e-07 30.3 0.1 3.4 3 0 0 3 3 3 3 Family of unknown function (DUF5578) SMC_hinge PF06470.13 CBZ34686.1 - 0.15 12.3 1.1 30 4.9 0.1 2.9 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain DnaJ PF00226.31 CBZ34687.1 - 0.00014 21.9 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Y_phosphatase2 PF03162.13 CBZ34688.1 - 4e-36 124.1 0.0 2.6e-27 95.4 0.0 2.1 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CBZ34688.1 - 0.00013 22.0 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PreAtp-grasp PF18604.1 CBZ34689.1 - 0.041 13.5 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 Pre ATP-grasp domain Ins_beta PF03488.14 CBZ34689.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type DASH_Spc34 PF08657.10 CBZ34689.1 - 0.093 12.5 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 DASH complex subunit Spc34 DUF2475 PF10629.9 CBZ34691.1 - 0.047 13.9 0.7 0.12 12.6 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) Raptor_N PF14538.6 CBZ34692.1 - 4e-46 156.6 0.0 6.4e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain RNA_pol_Rpb2_6 PF00562.28 CBZ34693.1 - 1.9e-72 244.5 0.0 1.2e-71 241.9 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 CBZ34693.1 - 2.2e-19 69.4 0.0 8.2e-19 67.6 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 CBZ34693.1 - 3.2e-14 53.1 0.0 7.6e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 CBZ34693.1 - 4.2e-10 39.5 0.1 3e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 PF04563.15 CBZ34693.1 - 1.4e-07 31.3 0.0 3.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_4 PF04566.13 CBZ34693.1 - 0.091 13.1 0.0 0.41 11.0 0.0 2.2 1 1 0 1 1 1 0 RNA polymerase Rpb2, domain 4 zinc_ribbon_10 PF10058.9 CBZ34693.1 - 0.14 11.9 0.1 0.39 10.5 0.1 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein PPR PF01535.20 CBZ34694.1 - 0.00099 19.2 0.3 0.0093 16.2 0.0 2.5 2 0 0 2 2 2 1 PPR repeat PPR_long PF17177.4 CBZ34694.1 - 0.0039 16.6 0.1 0.0057 16.0 0.1 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 CBZ34694.1 - 0.0061 16.7 0.4 0.062 13.5 0.0 2.6 2 1 1 3 3 3 1 PPR repeat family PPR_3 PF13812.6 CBZ34694.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 CBZ34694.1 - 0.013 15.2 0.0 0.042 13.6 0.0 2.0 1 0 0 1 1 1 0 PPR repeat zf-AN1 PF01428.16 CBZ34696.1 - 2.7 8.2 30.6 0.64 10.2 10.4 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger ENTH PF01417.20 CBZ34698.1 - 1.3e-26 93.1 0.0 2.5e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 ENTH domain CCDC50_N PF15295.6 CBZ34698.1 - 0.1 12.7 19.1 0.36 11.0 19.1 1.9 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Alpha_kinase PF02816.18 CBZ34699.1 - 4.8e-55 186.5 0.0 7.8e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family Draxin PF15550.6 CBZ34699.1 - 8.3 6.2 15.1 30 4.3 15.1 2.0 1 0 0 1 1 1 0 Draxin SCAMP PF04144.13 CBZ34702.1 - 1.2e-33 116.8 8.7 1.5e-33 116.5 8.7 1.1 1 0 0 1 1 1 1 SCAMP family FtsL PF04999.13 CBZ34702.1 - 2.8 8.0 5.0 1.1 9.4 1.2 2.2 2 0 0 2 2 2 0 Cell division protein FtsL Sugarporin_N PF11471.8 CBZ34702.1 - 9.2 6.3 6.1 1.9 8.5 1.6 2.3 2 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension eIF-5a PF01287.20 CBZ34704.1 - 4.9e-26 90.6 0.1 6.8e-26 90.2 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CBZ34704.1 - 0.00021 21.3 0.0 0.00044 20.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain eIF-5a PF01287.20 CBZ34705.1 - 4.9e-26 90.6 0.1 6.8e-26 90.2 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CBZ34705.1 - 0.00021 21.3 0.0 0.00044 20.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain SNF2_N PF00176.23 CBZ34707.1 - 2.6e-53 181.0 1.5 1.9e-27 95.9 0.0 3.5 2 2 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ34707.1 - 4e-18 65.8 0.0 1.8e-17 63.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-PARP PF00645.18 CBZ34707.1 - 1.4e-12 48.3 0.1 5.2e-12 46.5 0.1 2.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-RING_2 PF13639.6 CBZ34707.1 - 1.5e-06 28.4 3.6 1.5e-06 28.4 3.6 3.0 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 CBZ34707.1 - 5e-05 22.9 2.2 0.00013 21.6 2.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBZ34707.1 - 7.4e-05 22.5 4.6 7.4e-05 22.5 4.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ34707.1 - 0.00012 21.8 3.2 0.00012 21.8 3.2 3.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 CBZ34707.1 - 0.00035 19.8 0.0 0.0008 18.7 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase zf-rbx1 PF12678.7 CBZ34707.1 - 0.0032 17.7 3.0 0.0032 17.7 3.0 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ34707.1 - 0.014 15.4 1.1 0.049 13.7 1.1 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CBZ34707.1 - 0.047 13.7 3.3 0.2 11.7 3.3 2.2 1 0 0 1 1 1 0 RING-type zinc-finger PP2C PF00481.21 CBZ34708.1 - 1.1e-49 169.4 0.1 1.5e-49 169.0 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ34708.1 - 0.0031 17.2 0.0 0.0059 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CBZ34708.1 - 0.0041 17.1 0.0 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) TIP39 PF14980.6 CBZ34708.1 - 0.019 14.8 0.0 0.074 12.9 0.0 1.9 2 0 0 2 2 2 0 TIP39 peptide Spore_III_AB PF09548.10 CBZ34708.1 - 0.028 14.5 0.0 0.88 9.7 0.0 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Luciferase_N PF05295.11 CBZ34708.1 - 0.036 14.1 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Luciferase/LBP N-terminal domain Pdase_C33_assoc PF14756.6 CBZ34710.1 - 0.048 13.6 1.0 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 Peptidase_C33-associated domain HTH_53 PF18606.1 CBZ34710.1 - 0.14 11.9 1.6 0.38 10.4 0.2 2.1 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain TMEM171 PF15471.6 CBZ34711.1 - 0.51 9.3 2.0 0.88 8.5 2.0 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Ank_4 PF13637.6 CBZ34712.1 - 1.6e-09 38.1 1.3 0.0066 17.0 0.0 4.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ34712.1 - 1.9e-08 34.8 0.9 0.042 14.4 0.0 4.8 3 2 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ34712.1 - 0.00034 20.8 0.5 0.08 13.5 0.0 4.3 4 1 1 5 5 5 1 Ankyrin repeat LAT PF15234.6 CBZ34712.1 - 0.09 12.5 6.9 0.26 11.0 6.9 1.8 1 0 0 1 1 1 0 Linker for activation of T-cells DUF3318 PF11780.8 CBZ34712.1 - 0.49 10.3 4.0 19 5.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3318) zf-DNL PF05180.12 CBZ34713.1 - 1.1e-27 95.8 0.1 1.9e-27 95.0 0.1 1.4 1 0 0 1 1 1 1 DNL zinc finger DUF3094 PF11293.8 CBZ34713.1 - 0.033 13.9 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) zf-RING_4 PF14570.6 CBZ34713.1 - 0.064 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_4 PF13717.6 CBZ34713.1 - 0.11 12.4 0.0 0.29 11.1 0.0 1.7 2 0 0 2 2 2 0 zinc-ribbon domain Ashwin PF15323.6 CBZ34713.1 - 0.36 10.8 2.6 0.5 10.4 2.6 1.1 1 0 0 1 1 1 0 Developmental protein Cyclin_N PF00134.23 CBZ34714.1 - 7.3e-07 29.0 0.6 0.00073 19.3 0.0 3.3 3 0 0 3 3 3 2 Cyclin, N-terminal domain TFIIB_C_1 PF18542.1 CBZ34714.1 - 0.25 11.4 2.3 0.79 9.8 2.3 1.8 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 Prefoldin_2 PF01920.20 CBZ34715.1 - 2e-11 43.8 3.1 2.6e-11 43.4 3.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 CBZ34715.1 - 2.9e-06 27.2 4.1 0.00037 20.4 1.2 2.1 2 0 0 2 2 2 2 Prefoldin subunit TPR_MLP1_2 PF07926.12 CBZ34715.1 - 0.0024 17.9 3.4 0.046 13.8 2.1 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein XhlA PF10779.9 CBZ34715.1 - 0.0025 18.0 5.8 0.31 11.3 0.4 2.1 2 0 0 2 2 2 2 Haemolysin XhlA FapA PF03961.13 CBZ34715.1 - 0.0056 15.3 0.8 0.0069 15.0 0.8 1.0 1 0 0 1 1 1 1 Flagellar Assembly Protein A DUF5082 PF16888.5 CBZ34715.1 - 0.0062 16.8 1.7 0.2 12.0 0.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) CdvA PF18822.1 CBZ34715.1 - 0.011 15.6 2.2 0.019 14.8 2.2 1.4 1 1 0 1 1 1 0 CdvA-like coiled-coil domain AAA_lid_9 PF17871.1 CBZ34715.1 - 0.011 15.6 1.3 0.031 14.2 0.7 1.8 2 0 0 2 2 2 0 AAA lid domain CLZ PF16526.5 CBZ34715.1 - 0.013 15.8 4.4 0.096 13.1 1.4 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Med9 PF07544.13 CBZ34715.1 - 0.015 15.4 2.2 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 KfrA_N PF11740.8 CBZ34715.1 - 0.015 15.9 0.9 0.019 15.6 0.9 1.2 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF4140 PF13600.6 CBZ34715.1 - 0.015 15.7 2.8 3.7 8.1 0.6 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.11 CBZ34715.1 - 0.029 14.7 1.7 7.9 7.0 0.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PEP-utilisers_N PF05524.13 CBZ34715.1 - 0.06 13.5 2.1 0.12 12.6 0.5 1.9 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Baculo_PEP_C PF04513.12 CBZ34715.1 - 0.062 13.3 0.1 0.12 12.4 0.1 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.19 CBZ34715.1 - 0.075 10.9 0.4 0.086 10.7 0.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.22 CBZ34715.1 - 0.081 13.2 3.3 1 9.6 1.7 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Troponin PF00992.20 CBZ34715.1 - 0.16 12.2 5.6 0.51 10.6 5.6 1.8 1 1 1 2 2 2 0 Troponin Ead_Ea22 PF13935.6 CBZ34715.1 - 0.2 12.3 3.4 0.27 11.9 3.4 1.3 1 1 0 1 1 1 0 Ead/Ea22-like protein Spc24 PF08286.11 CBZ34715.1 - 0.21 11.8 5.9 0.77 10.0 2.2 2.1 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 THOC7 PF05615.13 CBZ34715.1 - 0.53 10.6 5.8 1.6 9.0 5.8 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 HR1 PF02185.16 CBZ34715.1 - 0.81 9.9 6.4 2.6 8.2 0.3 2.3 2 1 0 2 2 2 0 Hr1 repeat CCDC-167 PF15188.6 CBZ34715.1 - 0.95 9.8 7.7 3 8.2 7.7 1.7 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF4164 PF13747.6 CBZ34715.1 - 2.3 8.5 9.5 11 6.4 9.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) Kdo PF06293.14 CBZ34720.1 - 1.1e-06 28.1 0.1 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ34720.1 - 0.00057 19.5 0.0 0.85 9.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.25 CBZ34720.1 - 0.036 13.4 0.0 0.083 12.2 0.0 1.7 1 1 0 1 1 1 0 Protein kinase domain LRR_8 PF13855.6 CBZ34721.1 - 1.1e-25 89.2 6.5 1.2e-15 57.0 0.5 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBZ34721.1 - 9.1e-10 38.7 1.1 0.00024 21.4 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ34721.1 - 0.0027 18.0 5.5 0.033 14.7 0.2 4.0 4 1 1 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 CBZ34721.1 - 0.0065 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_5 PF13306.6 CBZ34721.1 - 0.038 14.0 0.0 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 CBZ34721.1 - 5.5 7.3 6.7 16 5.8 0.3 3.3 3 0 0 3 3 3 0 Leucine Rich repeat PKcGMP_CC PF16808.5 CBZ34721.1 - 6.9 6.6 12.7 1.2 9.0 0.3 4.4 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ribosomal_L23 PF00276.20 CBZ34722.1 - 4.9e-06 26.8 0.1 7.3e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 SPC25 PF06703.11 CBZ34723.1 - 2.5 7.9 6.2 14 5.4 0.6 2.3 1 1 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Pro_isomerase PF00160.21 CBZ34724.1 - 2.1e-45 154.9 0.0 2.3e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SLBP_RNA_bind PF15247.6 CBZ34725.1 - 5.5e-17 61.7 0.0 1.5e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain GAF_2 PF13185.6 CBZ34725.1 - 0.074 13.3 0.9 1 9.7 0.1 2.4 2 0 0 2 2 2 0 GAF domain Ank_4 PF13637.6 CBZ34726.1 - 1.5e-20 73.2 0.5 8.4e-09 35.8 0.1 3.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ34726.1 - 1.4e-16 60.9 0.0 7e-10 39.4 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ34726.1 - 1.1e-12 46.9 0.6 7.6e-05 22.8 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CBZ34726.1 - 1.4e-12 47.4 2.8 0.00017 21.9 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 CBZ34726.1 - 8.9e-11 41.8 1.9 5.7e-06 26.5 0.1 3.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) PUB PF09409.10 CBZ34728.1 - 0.0032 17.4 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 PUB domain Tubulin PF00091.25 CBZ34729.1 - 3e-67 226.7 0.0 4.4e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CBZ34729.1 - 2.9e-44 150.2 0.2 5.9e-44 149.3 0.2 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CBZ34729.1 - 1.1e-05 25.8 0.0 3.5e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CBZ34729.1 - 0.003 16.8 0.0 0.005 16.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin like Tubulin_3 PF14881.6 CBZ34729.1 - 0.04 13.6 0.0 0.097 12.4 0.0 1.6 2 0 0 2 2 2 0 Tubulin domain EF-hand_7 PF13499.6 CBZ34730.1 - 0.00077 19.9 0.0 0.066 13.7 0.0 3.3 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ34730.1 - 0.017 14.6 0.0 0.097 12.3 0.0 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 CBZ34730.1 - 0.047 13.6 0.0 1.5 9.0 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 CBZ34730.1 - 0.2 11.5 0.0 0.62 10.0 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair AAA_6 PF12774.7 CBZ34731.1 - 1.9e-144 480.6 0.9 4.9e-143 476.0 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CBZ34731.1 - 6.6e-143 477.3 13.8 6.6e-143 477.3 13.8 3.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CBZ34731.1 - 9.3e-114 380.6 3.6 9.3e-114 380.6 3.6 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ34731.1 - 1.5e-86 289.9 0.0 4e-86 288.5 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ34731.1 - 2.2e-77 260.3 0.4 1.5e-76 257.6 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ34731.1 - 3.3e-76 255.3 7.1 3.3e-76 255.3 7.1 2.4 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ34731.1 - 2.6e-53 180.2 3.1 7.7e-50 168.9 0.0 4.4 4 0 0 4 4 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ34731.1 - 1.5e-45 155.0 0.1 3.9e-44 150.4 0.1 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 CBZ34731.1 - 2.2e-38 132.2 7.9 2.2e-38 132.2 7.9 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CBZ34731.1 - 1.4e-37 128.4 2.1 1.9e-36 124.8 0.1 3.4 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 CBZ34731.1 - 3.7e-21 75.5 0.6 2.7e-20 72.8 0.2 2.9 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBZ34731.1 - 3.6e-14 52.9 0.0 0.0016 18.5 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CBZ34731.1 - 1.4e-11 44.5 0.0 2.6e-10 40.4 0.0 3.1 1 1 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CBZ34731.1 - 1.6e-06 28.6 1.2 0.049 14.1 0.0 5.4 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBZ34731.1 - 0.0098 16.4 0.1 0.38 11.3 0.0 3.6 3 0 0 3 3 2 1 AAA domain SNF5 PF04855.12 CBZ34731.1 - 0.012 15.4 0.1 6.4 6.5 0.1 3.1 2 0 0 2 2 2 0 SNF5 / SMARCB1 / INI1 PET PF06297.14 CBZ34731.1 - 0.088 13.1 0.0 0.37 11.1 0.0 2.2 1 0 0 1 1 1 0 PET Domain AAA_22 PF13401.6 CBZ34731.1 - 0.39 11.0 8.1 23 5.2 0.0 5.7 6 0 0 6 6 6 0 AAA domain Complex1_LYR PF05347.15 CBZ34732.1 - 2.3e-05 24.3 0.0 5.1e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) 2OG-FeII_Oxy PF03171.20 CBZ34734.1 - 1.3e-14 54.5 0.0 2.6e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CBZ34734.1 - 0.01 16.6 0.0 1.1 10.1 0.0 2.5 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal PrlF_antitoxin PF15937.5 CBZ34734.1 - 0.1 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin SecE PF00584.20 CBZ34735.1 - 1.6e-12 47.1 0.4 1.9e-12 46.9 0.4 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NAD_binding_2 PF03446.15 CBZ34736.1 - 4.3e-31 108.2 0.1 6.8e-31 107.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CBZ34736.1 - 6.4e-13 49.0 1.7 2.2e-11 44.0 0.1 2.9 3 0 0 3 3 3 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 CBZ34736.1 - 9e-05 22.6 0.3 0.0054 16.8 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CBZ34736.1 - 0.0034 17.9 0.1 0.028 15.0 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 CBZ34736.1 - 0.0061 17.4 0.0 0.77 10.6 0.0 2.9 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 CBZ34736.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PQQ_2 PF13360.6 CBZ34738.1 - 0.0062 16.2 3.1 0.014 15.0 3.1 1.5 1 0 0 1 1 1 1 PQQ-like domain Macoilin PF09726.9 CBZ34738.1 - 0.011 14.3 0.4 0.011 14.3 0.4 2.9 2 1 1 3 3 3 0 Macoilin family HTH_30 PF13556.6 CBZ34738.1 - 0.14 11.9 0.9 0.52 10.1 0.1 2.3 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain NPV_P10 PF05531.12 CBZ34738.1 - 0.24 11.9 1.8 0.56 10.7 0.2 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FAM184 PF15665.5 CBZ34738.1 - 0.57 9.9 12.3 0.064 13.0 4.9 2.4 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B His_kinase PF06580.13 CBZ34738.1 - 2.1 8.8 3.9 0.69 10.3 0.8 1.8 2 0 0 2 2 2 0 Histidine kinase Yuri_gagarin PF15934.5 CBZ34738.1 - 2.5 7.9 7.3 4.7 7.0 2.4 2.2 2 0 0 2 2 2 0 Yuri gagarin BBP1_C PF15272.6 CBZ34738.1 - 2.7 7.8 6.4 0.62 9.9 0.9 2.2 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Tup_N PF08581.10 CBZ34738.1 - 7.8 6.9 7.3 1.9 8.8 0.8 2.7 2 1 1 3 3 3 0 Tup N-terminal Frataxin_Cyay PF01491.16 CBZ34739.1 - 1.5e-28 99.0 0.0 2e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain CBM77 PF18283.1 CBZ34739.1 - 0.054 13.9 0.1 0.084 13.2 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding module 77 Phenol_Hydrox PF02332.18 CBZ34739.1 - 0.065 12.8 0.5 0.095 12.2 0.5 1.2 1 0 0 1 1 1 0 Methane/Phenol/Toluene Hydroxylase AATF-Che1 PF13339.6 CBZ34741.1 - 0.013 16.2 1.8 0.013 16.2 1.8 3.1 3 1 0 3 3 3 0 Apoptosis antagonizing transcription factor GAS PF13851.6 CBZ34741.1 - 1.1 8.5 17.2 1.1 8.6 5.3 3.7 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding RRM_1 PF00076.22 CBZ34742.1 - 0.0015 18.3 0.1 0.003 17.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2652 PF10851.8 CBZ34742.1 - 0.0017 18.5 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2652) CorA PF01544.18 CBZ34743.1 - 3.9e-19 69.1 0.2 1.3e-18 67.3 0.2 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF1217 PF06748.12 CBZ34743.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) DnaJ_C PF01556.18 CBZ34744.1 - 1.1e-31 109.9 0.0 1.6e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ34744.1 - 1.7e-17 63.3 1.0 2.7e-17 62.6 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ34744.1 - 2.3e-14 53.5 13.7 4.1e-14 52.7 13.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ34744.1 - 4.1e-08 33.1 7.4 0.0016 18.3 0.5 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein T6SS_TssF PF05947.12 CBZ34744.1 - 0.067 11.7 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssF Lar_restr_allev PF14354.6 CBZ34744.1 - 0.14 12.5 7.0 6.6 7.2 0.1 3.4 2 1 1 3 3 3 0 Restriction alleviation protein Lar Zn_ribbon_SprT PF17283.2 CBZ34744.1 - 0.65 10.0 10.7 2.2 8.2 3.4 3.3 2 1 0 2 2 2 0 SprT-like zinc ribbon domain TackOD1 PF18551.1 CBZ34744.1 - 0.67 9.6 7.9 0.2 11.3 1.0 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-RING_7 PF02591.15 CBZ34744.1 - 1.3 9.3 4.5 1.2 9.3 0.2 2.7 2 0 0 2 2 2 0 C4-type zinc ribbon domain DUF1356 PF07092.12 CBZ34744.1 - 1.4 8.1 7.9 0.41 9.9 0.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1356) HypA PF01155.19 CBZ34744.1 - 1.5 8.9 10.6 2.5 8.1 1.7 2.3 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CBZ34744.1 - 2.3 8.3 11.3 2.5 8.2 2.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 CBZ34744.1 - 3 8.2 14.1 3.9 7.8 0.3 3.6 2 2 2 4 4 4 0 zinc-ribbon Prok-RING_1 PF14446.6 CBZ34744.1 - 3.8 7.5 11.7 0.17 11.8 1.2 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.12 CBZ34744.1 - 4.4 7.4 9.4 37 4.4 9.4 2.1 1 1 0 1 1 1 0 zinc-ribbons DUF3797 PF12677.7 CBZ34744.1 - 6.2 6.8 5.4 7.5 6.5 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3797) DUF5351 PF17302.2 CBZ34744.1 - 7.4 6.9 15.6 11 6.4 0.8 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5351) Kelch_4 PF13418.6 CBZ34745.1 - 2e-06 27.7 0.4 0.002 18.1 0.1 3.0 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CBZ34745.1 - 0.00032 20.9 0.1 1.3 9.4 0.0 2.8 2 0 0 2 2 2 2 Kelch motif Kelch_1 PF01344.25 CBZ34745.1 - 0.00041 19.9 0.1 0.17 11.5 0.1 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 CBZ34745.1 - 0.039 13.9 2.3 23 5.1 0.0 3.8 3 0 0 3 3 3 0 Kelch motif GvpL_GvpF PF06386.11 CBZ34745.1 - 0.18 11.7 1.1 0.82 9.5 0.0 2.5 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Aldedh PF00171.22 CBZ34746.1 - 8.2e-177 588.3 0.2 9.2e-177 588.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CBZ34746.1 - 0.0061 16.0 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) LPD7 PF18821.1 CBZ34746.1 - 0.18 12.0 0.6 4.1 7.6 0.1 2.4 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 SBP_bac_3 PF00497.20 CBZ34747.1 - 0.038 13.4 0.0 2.5 7.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 SMI1_KNR4 PF09346.10 CBZ34748.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) Acetyltransf_16 PF05301.11 CBZ34749.1 - 5.7e-50 169.5 0.0 6.8e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase, Mec-17 Acetyltransf_1 PF00583.25 CBZ34749.1 - 0.0004 20.6 0.0 0.00085 19.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBZ34749.1 - 0.00085 19.7 0.0 0.0017 18.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBZ34749.1 - 0.009 16.0 0.0 0.028 14.4 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain LMBR1 PF04791.16 CBZ34750.1 - 4.7e-30 105.0 33.7 2e-22 79.8 9.6 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF3810 PF12725.7 CBZ34750.1 - 0.027 13.9 0.0 0.027 13.9 0.0 4.4 2 1 3 5 5 5 0 Protein of unknown function (DUF3810) DUF2721 PF11026.8 CBZ34750.1 - 0.058 13.3 0.1 0.058 13.3 0.1 5.4 4 2 3 7 7 7 0 Protein of unknown function (DUF2721) ATP-synt_ab PF00006.25 CBZ34751.1 - 6.5e-64 215.5 0.1 2.7e-63 213.5 0.0 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CBZ34751.1 - 1.2e-12 48.2 0.2 2.8e-12 47.0 0.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 CBZ34751.1 - 0.0045 17.4 0.1 0.029 14.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CBZ34751.1 - 0.016 15.6 1.5 0.28 11.5 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CBZ34751.1 - 0.017 14.7 0.2 0.095 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CBZ34751.1 - 0.035 13.3 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain ATPase PF06745.13 CBZ34751.1 - 0.036 13.4 0.1 0.062 12.6 0.1 1.4 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 CBZ34751.1 - 0.072 13.0 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 CBZ34751.1 - 0.1 12.5 0.1 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ribosomal_S25 PF03297.15 CBZ34752.1 - 1.5e-36 124.7 5.5 1.7e-36 124.4 5.5 1.1 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.8 CBZ34752.1 - 0.15 11.1 1.6 0.18 10.8 1.6 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3516) DNA_methylase PF00145.17 CBZ34753.1 - 5.5e-40 137.7 0.0 3.5e-30 105.5 0.0 3.7 2 1 0 3 3 3 3 C-5 cytosine-specific DNA methylase TAF4 PF05236.14 CBZ34754.1 - 0.13 12.0 2.6 0.32 10.7 2.6 1.6 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family PQQ_3 PF13570.6 CBZ34754.1 - 0.14 12.7 4.3 12 6.5 0.1 5.0 4 0 0 4 4 4 0 PQQ-like domain zinc_ribbon_16 PF17034.5 CBZ34757.1 - 1.9e-07 31.3 18.0 2.5e-06 27.7 18.0 2.2 1 1 0 1 1 1 1 Zinc-ribbon like family DUF776 PF05604.11 CBZ34757.1 - 0.02 15.3 1.0 0.27 11.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF776) zf-RING_2 PF13639.6 CBZ34757.1 - 0.25 11.7 7.4 0.85 10.0 7.4 1.9 1 0 0 1 1 1 0 Ring finger domain BRD4_CDT PF17105.5 CBZ34757.1 - 2.5 7.8 7.0 5.9 6.6 7.0 1.7 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 zinc_ribbon_16 PF17034.5 CBZ34758.1 - 0.0015 18.7 23.9 0.028 14.6 23.9 2.4 1 1 0 1 1 1 1 Zinc-ribbon like family zinc_ribbon_16 PF17034.5 CBZ34759.1 - 0.0015 18.7 23.9 0.028 14.6 23.9 2.4 1 1 0 1 1 1 1 Zinc-ribbon like family Med3 PF11593.8 CBZ34760.1 - 0.11 11.6 13.6 1.3 8.2 7.0 2.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal BSD PF03909.17 CBZ34760.1 - 0.21 11.6 2.2 0.27 11.3 0.3 2.1 3 0 0 3 3 3 0 BSD domain Microtub_bind PF13931.6 CBZ34760.1 - 1.4 9.3 3.8 1.1 9.7 0.9 2.1 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding Cullin PF00888.22 CBZ34761.1 - 4.5e-51 174.2 0.0 2.1e-50 172.0 0.0 2.0 1 1 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBZ34761.1 - 6.8e-07 29.2 0.0 2.5e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain NPL4 PF05021.15 CBZ34762.1 - 7e-06 25.6 0.0 0.0001 21.8 0.0 2.1 2 0 0 2 2 2 1 NPL4 family FLYWCH_N PF15423.6 CBZ34762.1 - 0.066 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 FLYWCH-type zinc finger-containing protein PRP38 PF03371.15 CBZ34763.1 - 3.5e-05 23.7 0.0 5.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 PRP38 family MbeB_N PF04837.12 CBZ34763.1 - 0.045 14.0 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region PPP4R2 PF09184.11 CBZ34764.1 - 0.00027 20.6 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 PPP4R2 RNA_pol_N PF01194.17 CBZ34765.1 - 1.2e-29 102.3 0.7 1.5e-29 102.0 0.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit UBA PF00627.31 CBZ34765.1 - 0.11 12.4 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 UBA/TS-N domain Metallophos PF00149.28 CBZ34766.1 - 1.4e-33 117.2 1.1 1.9e-33 116.7 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GIY-YIG PF01541.24 CBZ34767.1 - 2.4e-11 43.8 0.0 4.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain RNF220 PF15926.5 CBZ34767.1 - 0.18 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 T5orf172 PF10544.9 CBZ34767.1 - 0.21 12.1 0.2 0.95 10.0 0.0 2.1 2 0 0 2 2 2 0 T5orf172 domain Sec23_trunk PF04811.15 CBZ34768.1 - 2.7e-39 135.2 0.0 4.3e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CBZ34768.1 - 4.6e-21 74.6 0.0 8.8e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CBZ34768.1 - 6.2e-17 62.1 0.1 1.2e-16 61.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CBZ34768.1 - 2.7e-10 40.1 0.9 8.1e-10 38.6 0.9 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger ASH PF15780.5 CBZ34769.1 - 1.4e-09 38.0 10.9 4.3e-06 26.8 0.1 6.7 6 1 1 7 7 7 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 CBZ34769.1 - 0.021 15.1 6.8 0.056 13.7 0.1 4.6 6 1 0 6 6 6 0 Transmembrane protein 131-like TAP42 PF04177.12 CBZ34771.1 - 2.6e-44 151.6 9.0 4e-43 147.7 9.0 2.0 1 1 0 1 1 1 1 TAP42-like family Sec3_C PF09763.9 CBZ34772.1 - 0.11 10.8 0.1 0.14 10.5 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 RMF PF04957.12 CBZ34772.1 - 0.32 11.3 3.0 10 6.5 0.5 2.3 2 0 0 2 2 2 0 Ribosome modulation factor ATP_bind_1 PF03029.17 CBZ34773.1 - 2.8e-62 210.6 0.0 3.3e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 CBZ34773.1 - 0.00019 21.2 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ34773.1 - 0.00089 19.8 0.0 0.0019 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CBZ34773.1 - 0.0015 19.0 0.0 0.0033 17.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SRP54 PF00448.22 CBZ34773.1 - 0.0025 17.5 0.1 0.0054 16.4 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CBZ34773.1 - 0.0051 17.1 0.0 0.0094 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 CBZ34773.1 - 0.0075 16.1 0.0 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 CBZ34773.1 - 0.0094 16.3 0.0 0.015 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CBZ34773.1 - 0.018 14.8 0.1 0.039 13.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 CBZ34773.1 - 0.02 14.5 0.0 0.91 9.0 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 CBZ34773.1 - 0.023 14.9 0.0 0.038 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CBZ34773.1 - 0.024 14.7 0.0 0.23 11.6 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 CBZ34773.1 - 0.025 14.3 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 Cytidylate kinase RsgA_GTPase PF03193.16 CBZ34773.1 - 0.041 13.8 0.0 0.37 10.7 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase RNA_helicase PF00910.22 CBZ34773.1 - 0.046 14.1 0.6 0.26 11.7 0.1 2.4 2 1 1 3 3 3 0 RNA helicase AAA_17 PF13207.6 CBZ34773.1 - 0.049 14.1 0.1 0.15 12.5 0.1 1.7 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CBZ34773.1 - 0.054 13.2 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 CBZ34773.1 - 0.13 11.9 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CBZ34773.1 - 0.15 12.1 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 CBZ34773.1 - 0.16 11.9 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arm PF00514.23 CBZ34773.1 - 0.18 11.9 0.1 0.65 10.1 0.0 2.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Surp PF01805.20 CBZ34774.1 - 7.9e-15 54.6 4.0 2.1e-12 46.8 0.2 2.6 3 0 0 3 3 3 2 Surp module DNA_pol_D_N PF18018.1 CBZ34775.1 - 8.4e-28 97.1 0.0 1.7e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DNA_pol_E_B PF04042.16 CBZ34775.1 - 1.3e-23 83.5 0.8 3.1e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Ras PF00071.22 CBZ34776.1 - 2.1e-50 170.5 0.0 2.6e-50 170.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ34776.1 - 6.2e-32 110.3 0.0 1.1e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ34776.1 - 5.2e-11 42.3 0.0 7.1e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ34776.1 - 0.00027 20.4 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 CBZ34776.1 - 0.00033 21.0 0.2 0.0021 18.4 0.2 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 CBZ34776.1 - 0.00033 20.7 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CBZ34776.1 - 0.0068 15.6 1.1 1.2 8.2 0.1 2.7 2 1 1 3 3 3 1 G-protein alpha subunit RsgA_GTPase PF03193.16 CBZ34776.1 - 0.008 16.1 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CBZ34776.1 - 0.018 14.6 0.4 0.071 12.6 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 CBZ34776.1 - 0.029 13.9 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CBZ34776.1 - 0.036 14.2 0.0 0.054 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 CBZ34776.1 - 0.041 13.3 0.1 0.075 12.5 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein cobW PF02492.19 CBZ34776.1 - 0.079 12.5 0.1 3.7 7.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CBZ34776.1 - 0.08 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 CBZ34776.1 - 0.094 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CBZ34776.1 - 0.098 12.4 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CBZ34776.1 - 0.1 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin Cluap1 PF10234.9 CBZ34777.1 - 3e-89 299.0 13.6 4.3e-89 298.5 13.6 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Lectin_N PF03954.14 CBZ34777.1 - 0.55 10.0 6.4 0.14 11.9 0.9 2.4 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Atg14 PF10186.9 CBZ34777.1 - 1 8.4 9.7 2 7.5 9.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 XhlA PF10779.9 CBZ34777.1 - 6.2 7.1 10.3 17 5.7 1.8 2.7 2 0 0 2 2 2 0 Haemolysin XhlA Jnk-SapK_ap_N PF09744.9 CBZ34777.1 - 9.7 6.4 20.7 0.59 10.3 9.9 2.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 RNase_T PF00929.24 CBZ34778.1 - 8.5e-06 26.4 0.0 1.4e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DUF1295 PF06966.12 CBZ34780.1 - 6.1e-08 32.5 1.4 7.4e-08 32.2 0.5 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CBZ34780.1 - 0.00013 22.3 0.9 0.00013 22.3 0.9 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 CBZ34780.1 - 0.0031 17.5 1.1 0.005 16.8 0.7 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Rod_cone_degen PF15201.6 CBZ34780.1 - 0.083 13.0 2.1 0.12 12.5 0.7 2.0 2 0 0 2 2 2 0 Progressive rod-cone degeneration PCRF PF03462.18 CBZ34781.1 - 1.8e-30 106.3 0.2 1.8e-30 106.3 0.2 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CBZ34781.1 - 9.7e-26 90.0 0.2 2.2e-25 88.8 0.2 1.6 1 0 0 1 1 1 1 RF-1 domain CsiV PF10972.8 CBZ34781.1 - 0.02 14.6 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV DUF1126 PF06565.12 CBZ34782.1 - 6.6e-69 228.4 0.3 6.7e-26 90.2 0.0 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 CBZ34782.1 - 0.0067 16.8 0.3 0.22 12.0 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain pair Cyclin_N PF00134.23 CBZ34783.1 - 2.9e-38 130.5 0.7 4.2e-38 130.0 0.7 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBZ34783.1 - 4.4e-14 52.6 0.0 7.6e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Rhodopsin_N PF10413.9 CBZ34783.1 - 0.013 15.3 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin NfI_DNAbd_pre-N PF10524.9 CBZ34783.1 - 0.038 13.9 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Peptidase_C2 PF00648.21 CBZ34784.1 - 3.6e-64 216.6 0.1 5.2e-64 216.1 0.1 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ34784.1 - 1.5e-25 89.5 0.1 3.6e-25 88.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Rab3-GTPase_cat PF13890.6 CBZ34785.1 - 1.8e-44 151.3 0.2 3.9e-44 150.1 0.0 1.7 2 0 0 2 2 2 1 Rab3 GTPase-activating protein catalytic subunit Methyltr_RsmB-F PF01189.17 CBZ34786.1 - 3.4e-22 79.1 0.0 1.3e-14 54.3 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PUA PF01472.20 CBZ34786.1 - 3e-07 30.3 0.1 6.3e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 PUA domain Pkinase PF00069.25 CBZ34788.1 - 1.6e-42 145.7 0.0 2.1e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34788.1 - 5.9e-30 104.4 0.0 8e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ34788.1 - 1.3e-06 27.5 0.0 2.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ34788.1 - 0.0024 17.3 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ34788.1 - 0.01 15.7 2.3 0.056 13.3 0.1 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 CBZ34788.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_ATPase PF09818.9 CBZ34790.1 - 7.2e-175 582.1 0.0 9.3e-175 581.7 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 CBZ34790.1 - 0.003 18.1 0.0 0.0051 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain zf-Tim10_DDP PF02953.15 CBZ34791.1 - 0.00071 19.2 0.2 0.0012 18.4 0.2 1.4 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Antimicrobial21 PF14861.6 CBZ34791.1 - 0.087 12.5 0.3 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Plant antimicrobial peptide Pkinase PF00069.25 CBZ34792.1 - 1.4e-26 93.4 0.0 6.7e-15 55.2 0.0 3.5 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34792.1 - 1.7e-06 27.5 0.0 0.16 11.2 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CBZ34792.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TRAPPC-Trs85 PF12739.7 CBZ34793.1 - 1.3e-36 126.5 0.1 2.1e-36 125.8 0.1 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_1 PF00515.28 CBZ34793.1 - 9.2 6.3 6.5 3.2 7.7 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 CBZ34794.1 - 8e-26 91.0 0.0 2.4e-20 73.0 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34794.1 - 2e-12 47.0 0.0 3.5e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ34794.1 - 3.2e-05 22.9 0.0 4.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ34794.1 - 0.0088 16.0 0.0 0.049 13.6 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family BRCT PF00533.26 CBZ34795.1 - 0.00028 21.2 0.0 0.0032 17.8 0.0 2.7 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CBZ34795.1 - 0.01 16.3 0.0 1.2 9.6 0.0 3.3 3 0 0 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain WD40 PF00400.32 CBZ34796.1 - 1.9e-15 57.0 13.3 0.036 14.9 0.0 10.0 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ34796.1 - 4.1e-06 27.0 0.4 0.032 14.5 0.0 4.3 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain JAB PF01398.21 CBZ34797.1 - 0.0001 22.3 0.0 0.00028 20.8 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UPF0172 PF03665.13 CBZ34797.1 - 0.088 12.9 0.1 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) DAGAT PF03982.13 CBZ34799.1 - 2.2e-78 263.2 0.0 2.8e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF1016_N PF17761.1 CBZ34800.1 - 0.0083 16.3 0.2 0.028 14.6 0.0 1.9 2 0 0 2 2 2 1 DUF1016 N-terminal domain KOW PF00467.29 CBZ34800.1 - 0.016 15.1 0.5 0.044 13.7 0.5 1.7 1 0 0 1 1 1 0 KOW motif ribosomal_L24 PF17136.4 CBZ34800.1 - 0.035 14.5 0.0 0.082 13.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 DUF3410 PF11890.8 CBZ34800.1 - 0.081 12.7 0.3 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) COX6B PF02297.17 CBZ34801.1 - 0.0046 17.2 5.5 0.013 15.7 5.4 1.7 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 CBZ34801.1 - 0.046 13.9 5.5 0.088 13.0 0.5 2.3 2 0 0 2 2 2 0 CHCH domain CX9C PF16860.5 CBZ34801.1 - 0.089 12.8 0.6 0.089 12.8 0.6 2.5 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 CBZ34801.1 - 0.47 10.7 5.4 1.6 9.1 5.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) EFP_N PF08207.12 CBZ34802.1 - 9.4e-06 25.6 0.4 1.7e-05 24.8 0.4 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain HORMA PF02301.18 CBZ34804.1 - 6.2e-17 61.9 0.0 9.9e-17 61.2 0.0 1.3 1 1 0 1 1 1 1 HORMA domain TPR_12 PF13424.6 CBZ34805.1 - 2e-14 53.6 17.9 5.7e-07 29.7 1.9 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ34805.1 - 1.6e-05 24.7 2.7 1.6 9.0 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ34805.1 - 0.4 11.4 2.0 11 6.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HSCB_C PF07743.13 CBZ34806.1 - 0.00096 19.6 0.0 0.085 13.4 0.0 2.5 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CBZ34806.1 - 0.0048 17.0 1.9 0.035 14.2 0.4 2.4 2 0 0 2 2 2 1 DnaJ domain LRR_9 PF14580.6 CBZ34807.1 - 1e-12 47.9 0.0 2.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 CBZ34807.1 - 2.1e-07 30.6 3.8 1.6e-05 24.6 0.5 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBZ34807.1 - 5e-07 30.0 2.0 0.00035 20.9 0.3 3.3 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ34807.1 - 0.0048 16.9 1.1 13 6.1 0.0 3.9 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 CBZ34807.1 - 0.022 15.3 0.1 18 6.4 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat LSM PF01423.22 CBZ34808.1 - 5.7e-14 51.6 0.0 7.7e-14 51.1 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ34808.1 - 0.035 14.3 0.0 0.2 11.8 0.0 2.0 1 1 0 1 1 1 0 Ataxin 2 SM domain Transket_pyr PF02779.24 CBZ34809.1 - 1.4e-43 148.6 0.0 2.1e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBZ34809.1 - 9.9e-40 135.3 0.0 2.4e-39 134.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CBZ34809.1 - 0.099 13.0 0.0 0.52 10.6 0.0 2.2 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II DUF1935 PF09149.10 CBZ34813.1 - 1.6e-27 95.9 0.0 1.9e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) RMI1_N PF08585.12 CBZ34814.1 - 6.3e-11 42.4 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 RecQ mediated genome instability protein BRCA-2_OB1 PF09103.10 CBZ34814.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.6 1 1 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Steroid_dh PF02544.16 CBZ34815.1 - 2e-24 86.3 2.4 3.3e-24 85.6 2.4 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CBZ34815.1 - 7.8e-05 22.3 1.0 0.00014 21.5 0.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ubiquitin PF00240.23 CBZ34815.1 - 0.046 13.5 0.0 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin family PEMT PF04191.13 CBZ34815.1 - 0.097 13.1 4.7 0.13 12.7 0.7 2.3 1 1 1 2 2 2 0 Phospholipid methyltransferase YukD PF08817.10 CBZ34815.1 - 0.18 12.5 0.1 0.4 11.4 0.1 1.5 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Dala_Dala_lig_C PF07478.13 CBZ34816.1 - 1.3e-14 54.2 0.0 2.7e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus SET PF00856.28 CBZ34816.1 - 2.5e-06 28.0 0.1 2e-05 25.1 0.0 2.1 2 1 0 2 2 2 1 SET domain ATP-grasp_3 PF02655.14 CBZ34816.1 - 3.9e-05 23.7 0.0 0.00019 21.5 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 CBZ34816.1 - 0.0014 18.2 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Herpes_capsid PF06112.11 CBZ34816.1 - 0.0041 17.2 17.8 0.0073 16.4 17.8 1.3 1 0 0 1 1 1 1 Gammaherpesvirus capsid protein RimK PF08443.11 CBZ34816.1 - 0.0048 16.5 0.0 0.0097 15.5 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 CBZ34816.1 - 0.023 13.9 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 CBZ34816.1 - 0.043 13.4 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 CBZ34816.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain FAM199X PF15814.5 CBZ34816.1 - 1.8 7.5 13.7 3.1 6.8 13.7 1.3 1 0 0 1 1 1 0 Protein family FAM199X CHAP PF05257.16 CBZ34817.1 - 1.7e-05 25.3 0.1 3.4e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 CHAP domain zinc_ribbon_16 PF17034.5 CBZ34818.1 - 2.5e-05 24.5 12.5 0.037 14.2 0.2 2.4 2 0 0 2 2 2 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 CBZ34818.1 - 0.063 12.9 18.6 0.038 13.6 14.9 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Thioredoxin PF00085.20 CBZ34819.1 - 0.0054 16.7 0.0 0.0099 15.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF4542 PF15075.6 CBZ34820.1 - 0.0076 16.6 0.2 0.035 14.5 0.2 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4542) SLBP_RNA_bind PF15247.6 CBZ34821.1 - 3.1e-23 81.7 4.1 7.4e-23 80.5 4.1 1.7 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain Not3 PF04065.15 CBZ34822.1 - 1e-61 208.3 23.3 1.9e-61 207.4 23.3 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CBZ34822.1 - 1.2e-34 119.2 9.4 5.1e-34 117.2 9.4 2.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 CBZ34822.1 - 0.00033 21.0 0.9 0.00033 21.0 0.9 2.5 2 1 0 2 2 2 1 Syntaxin-like protein WD40 PF00400.32 CBZ34823.1 - 7.6e-20 70.9 7.8 0.0015 19.4 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ34823.1 - 1.5e-07 31.6 0.0 0.055 13.8 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4589 PF15252.6 CBZ34823.1 - 0.15 12.0 1.4 0.22 11.5 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4589) TPM_phosphatase PF04536.14 CBZ34824.1 - 4e-18 65.8 0.0 5.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 TPM domain zf-IS66 PF13005.7 CBZ34824.1 - 0.54 10.7 0.0 0.54 10.7 0.0 3.5 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 Vicilin_N PF04702.12 CBZ34825.1 - 0.7 9.7 7.1 1.1 9.1 3.9 2.1 2 0 0 2 2 2 0 Vicilin N terminal region Vps55 PF04133.14 CBZ34826.1 - 7.2e-27 93.7 5.3 8.7e-27 93.4 5.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF308 PF03729.13 CBZ34826.1 - 0.14 12.5 11.4 0.72 10.2 5.0 2.4 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Phage_holin_3_6 PF07332.11 CBZ34826.1 - 1.3 9.1 10.8 5.1 7.2 0.4 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III MARVEL PF01284.23 CBZ34826.1 - 1.8 8.6 10.4 2 8.4 2.7 2.1 2 0 0 2 2 2 0 Membrane-associating domain PAC3 PF10178.9 CBZ34827.1 - 0.0011 19.1 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 DFP PF04127.15 CBZ34828.1 - 1.1e-20 74.3 0.0 9.7e-10 38.6 0.0 2.3 1 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein DNA_repr_REX1B PF14966.6 CBZ34829.1 - 0.00038 21.1 2.5 0.0089 16.7 0.6 2.3 2 0 0 2 2 2 2 DNA repair REX1-B TPR_MalT PF17874.1 CBZ34830.1 - 3.1e-08 33.4 23.3 1e-07 31.7 4.8 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_12 PF13424.6 CBZ34830.1 - 9.1e-08 32.3 30.0 0.00011 22.5 2.9 4.7 1 1 3 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ34830.1 - 6.3e-05 22.7 19.3 0.0017 18.2 0.6 5.6 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ34830.1 - 0.0071 16.1 10.1 0.08 12.8 0.1 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat DHR-2 PF06920.13 CBZ34830.1 - 0.087 11.4 0.3 0.14 10.8 0.3 1.2 1 0 0 1 1 1 0 Dock homology region 2 TPR_2 PF07719.17 CBZ34830.1 - 0.26 11.5 0.2 0.26 11.5 0.2 6.8 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ34830.1 - 0.72 10.8 30.7 1.5 9.9 0.1 7.0 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ34830.1 - 2 9.2 25.4 2 9.1 7.6 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ34830.1 - 3.5 8.1 9.6 6.8 7.2 0.1 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CBZ34830.1 - 4.5 7.4 12.4 4.7 7.4 0.1 3.5 2 2 0 3 3 3 0 Anaphase-promoting complex subunit 5 RRM_1 PF00076.22 CBZ34831.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 CBZ34833.1 - 2.3e-78 263.5 0.2 2.3e-78 263.5 0.2 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ34833.1 - 7.9e-22 77.8 0.2 2.9e-21 76.0 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding FapA PF03961.13 CBZ34833.1 - 0.0035 16.0 4.9 0.0064 15.1 4.9 1.4 1 0 0 1 1 1 1 Flagellar Assembly Protein A Helicase_C_2 PF13307.6 CBZ34833.1 - 0.048 13.8 0.2 0.12 12.5 0.2 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain DUF5339 PF17274.2 CBZ34833.1 - 0.25 12.2 2.3 9.9 7.1 1.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5339) ResIII PF04851.15 CBZ34833.1 - 0.32 11.0 1.9 0.51 10.3 0.1 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF445 PF04286.12 CBZ34833.1 - 1.2 8.9 7.2 0.4 10.4 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF445) PIN_8 PF18476.1 CBZ34833.1 - 1.5 8.6 12.0 9.7 6.0 8.1 2.7 2 1 0 2 2 2 0 PIN like domain AAA_16 PF13191.6 CBZ34833.1 - 2.7 8.4 9.0 6.7 7.1 0.0 3.9 3 1 0 3 3 3 0 AAA ATPase domain Kinesin PF00225.23 CBZ34835.1 - 1e-101 340.2 0.0 1.7e-101 339.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ34835.1 - 5.1e-25 88.2 0.0 1.6e-24 86.5 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 CBZ34835.1 - 0.21 11.1 0.0 0.44 10.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 CBZ34835.1 - 0.22 11.8 0.0 0.22 11.8 0.0 3.6 4 1 0 4 4 4 0 AAA domain DUF812 PF05667.11 CBZ34835.1 - 0.3 9.9 30.1 0.038 12.9 12.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF812) MMS19_N PF14500.6 CBZ34836.1 - 0.13 11.8 0.2 0.39 10.3 0.0 1.8 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Pkinase PF00069.25 CBZ34837.1 - 3.4e-57 193.8 0.0 5.6e-42 143.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34837.1 - 6.6e-33 114.1 0.0 4.5e-24 85.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ34837.1 - 1.3e-05 24.2 0.0 2.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ34837.1 - 0.00037 19.9 0.0 0.083 12.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CBZ34837.1 - 0.0059 16.0 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ34837.1 - 0.0094 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ34837.1 - 0.043 13.4 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Iso_dh PF00180.20 CBZ34837.1 - 0.2 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Isocitrate/isopropylmalate dehydrogenase K_channel_TID PF07941.11 CBZ34838.1 - 7.4 7.1 12.2 2.4 8.6 0.8 2.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain HpcH_HpaI PF03328.14 CBZ34839.1 - 1.3e-54 184.7 0.0 1.6e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DHQS PF01959.16 CBZ34839.1 - 0.054 12.4 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase II rRNA_methylase PF06962.12 CBZ34839.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative rRNA methylase Zeta_toxin PF06414.12 CBZ34840.1 - 7.4e-05 22.1 0.0 0.26 10.6 0.0 2.3 1 1 1 2 2 2 2 Zeta toxin Cytidylate_kin PF02224.18 CBZ34840.1 - 0.0022 17.8 0.1 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase AAA_16 PF13191.6 CBZ34840.1 - 0.0024 18.3 0.1 0.0084 16.5 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CBZ34840.1 - 0.0035 17.3 0.1 0.0058 16.6 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain SRP54 PF00448.22 CBZ34840.1 - 0.013 15.1 0.5 0.083 12.5 0.2 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ribosomal_S7 PF00177.21 CBZ34840.1 - 0.026 14.2 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S7p/S5e AAA_30 PF13604.6 CBZ34840.1 - 0.031 14.0 0.0 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBZ34840.1 - 0.048 14.2 0.2 0.2 12.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF1456 PF07308.13 CBZ34840.1 - 0.054 13.8 1.7 0.49 10.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1456) PIF1 PF05970.14 CBZ34840.1 - 0.054 12.6 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_33 PF13671.6 CBZ34840.1 - 0.06 13.5 0.1 0.11 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CBZ34840.1 - 0.066 13.6 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain PEPCK_ATP PF01293.20 CBZ34840.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Ploopntkinase2 PF18747.1 CBZ34840.1 - 0.14 11.4 0.0 0.32 10.2 0.0 1.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase2 NIF PF03031.18 CBZ34841.1 - 4.9e-49 166.1 0.1 7.3e-49 165.5 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase G-alpha PF00503.20 CBZ34841.1 - 0.0033 16.6 0.0 0.0051 16.0 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit DUF2777 PF10949.8 CBZ34841.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2777) SNF2_N PF00176.23 CBZ34843.1 - 5.3e-40 137.2 0.2 9e-40 136.5 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ34843.1 - 4.4e-17 62.4 0.0 9.1e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.29 CBZ34843.1 - 6.6e-07 29.1 12.5 0.0037 17.1 2.1 2.7 2 0 0 2 2 2 2 PHD-finger ResIII PF04851.15 CBZ34843.1 - 2.2e-06 27.8 0.0 3.5e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBZ34843.1 - 0.00026 20.8 0.0 0.0007 19.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-PHD-like PF15446.6 CBZ34843.1 - 0.0093 15.6 6.9 0.067 12.8 0.7 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain SWI2_SNF2 PF18766.1 CBZ34843.1 - 0.023 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase HDA2-3 PF11496.8 CBZ34843.1 - 0.024 13.8 0.0 0.054 12.6 0.0 1.5 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 GET2 PF08690.10 CBZ34843.1 - 0.031 14.0 5.2 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 Prok-RING_1 PF14446.6 CBZ34843.1 - 8.9 6.3 17.6 8.2 6.5 5.0 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 SpoIIE PF07228.12 CBZ34844.1 - 3.9e-15 56.3 0.2 4.7e-14 52.7 0.2 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CBZ34844.1 - 5.9e-06 26.1 0.1 1.3e-05 25.0 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CBZ34844.1 - 0.00052 19.7 0.0 0.0055 16.4 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C Rieske PF00355.26 CBZ34845.1 - 5.9e-07 29.3 0.2 1.4e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CBZ34845.1 - 1.7e-06 27.9 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain NAD_binding_1 PF00175.21 CBZ34845.1 - 0.009 16.6 0.0 4.4 8.0 0.0 2.5 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain Dak1_2 PF13684.6 CBZ34845.1 - 0.13 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family GTP_EFTU PF00009.27 CBZ34846.1 - 5.7e-51 172.8 0.0 1.2e-50 171.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CBZ34846.1 - 2.2e-16 59.6 0.0 5.2e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CBZ34846.1 - 6.9e-08 32.8 0.1 1.5e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 CBZ34846.1 - 1.3e-06 28.2 0.0 3.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 CBZ34846.1 - 0.00034 20.6 0.0 0.0023 18.0 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II cobW PF02492.19 CBZ34846.1 - 0.049 13.2 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.22 CBZ34846.1 - 0.13 11.9 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 CBZ34846.1 - 0.15 11.9 0.4 0.38 10.6 0.3 1.7 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 CBZ34846.1 - 0.18 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit mRNA_triPase PF02940.15 CBZ34848.1 - 8.4e-12 45.3 0.0 9.9e-11 41.8 0.0 2.2 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain Trp_syntA PF00290.20 CBZ34848.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.4 1 1 0 1 1 1 0 Tryptophan synthase alpha chain TPR_2 PF07719.17 CBZ34849.1 - 7.1e-18 63.2 21.5 0.0051 16.8 0.0 7.2 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ34849.1 - 5.2e-13 48.2 16.7 0.00036 20.2 0.1 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ34849.1 - 5e-10 38.8 17.7 0.0043 17.1 0.1 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ34849.1 - 7.8e-08 32.5 16.7 0.0021 18.3 1.0 5.1 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ34849.1 - 6e-07 29.8 11.4 0.061 14.2 0.2 5.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ34849.1 - 7.9e-06 26.4 21.6 0.083 13.5 0.6 4.8 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ34849.1 - 3e-05 24.4 6.8 0.53 10.8 0.1 4.8 2 2 3 5 5 5 1 Tetratricopeptide repeat zf-C2H2_10 PF16588.5 CBZ34849.1 - 4e-05 23.2 2.2 0.00011 21.9 2.2 1.7 1 0 0 1 1 1 1 C2H2 zinc-finger TPR_11 PF13414.6 CBZ34849.1 - 0.00094 18.8 13.2 0.55 10.0 1.1 6.3 6 1 1 7 7 7 2 TPR repeat TPR_6 PF13174.6 CBZ34849.1 - 0.0012 19.4 5.6 11 6.9 0.0 5.6 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ34849.1 - 0.003 17.8 7.5 0.16 12.4 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat zf-CCHC PF00098.23 CBZ34849.1 - 0.0034 17.4 1.3 0.0067 16.5 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle ANAPC3 PF12895.7 CBZ34849.1 - 0.014 15.6 14.1 0.74 10.1 1.1 4.5 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-CCHC_2 PF13696.6 CBZ34849.1 - 0.016 15.0 0.4 0.028 14.2 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle Fis1_TPR_C PF14853.6 CBZ34849.1 - 0.022 14.8 2.4 2.4 8.3 0.1 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Mgm101p PF06420.12 CBZ34849.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 NYD-SP12_N PF15015.6 CBZ34849.1 - 0.039 12.3 0.4 0.075 11.4 0.1 1.5 2 0 0 2 2 2 0 Spermatogenesis-associated, N-terminal TPR_3 PF07720.12 CBZ34849.1 - 0.29 11.2 3.7 9.5 6.3 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CBZ34849.1 - 0.7 10.0 11.3 2.3 8.4 0.3 4.1 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CBZ34849.1 - 1.8 8.6 12.0 4.5 7.3 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat KBP_C PF12309.8 CBZ34850.1 - 6.9e-49 167.3 2.6 1.6e-47 162.8 0.4 2.9 2 1 0 2 2 2 1 KIF-1 binding protein C terminal NRN1 PF15056.6 CBZ34850.1 - 0.054 13.6 0.2 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 Neuritin protein family RNA_polI_A14 PF08203.11 CBZ34850.1 - 0.12 13.2 0.1 0.55 11.0 0.0 2.2 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 TPR_7 PF13176.6 CBZ34850.1 - 0.75 10.0 4.0 11 6.3 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat eIF3_subunit PF08597.10 CBZ34851.1 - 4.9e-11 43.0 11.9 6.5e-11 42.6 11.9 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit WASH-7_C PF14746.6 CBZ34851.1 - 0.41 10.3 2.1 0.44 10.2 0.1 1.9 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal CoA_binding PF02629.19 CBZ34852.1 - 1.4e-27 96.2 4.0 1.6e-27 96.0 2.4 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CBZ34852.1 - 8.2e-23 80.9 0.7 1.3e-22 80.3 0.1 1.6 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 CBZ34852.1 - 4e-09 36.4 0.0 8.1e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CBZ34852.1 - 0.00074 20.0 0.1 0.0015 19.0 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain BRO1 PF03097.18 CBZ34854.1 - 2.6e-24 85.8 0.0 3.1e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain KIX PF02172.16 CBZ34854.1 - 0.067 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 KIX domain Kre28 PF17097.5 CBZ34855.1 - 0.53 9.2 2.7 1.7 7.6 0.1 2.4 3 0 0 3 3 3 0 Spindle pole body component Rad60-SLD PF11976.8 CBZ34856.1 - 1.4e-05 24.8 0.3 2.3e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CBZ34856.1 - 0.00016 21.4 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family CLP1_P PF16575.5 CBZ34857.1 - 2.5e-18 66.5 0.0 4.2e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CBZ34857.1 - 2.8e-07 30.7 0.0 4.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CbiA PF01656.23 CBZ34857.1 - 0.00068 19.7 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CBZ34857.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sec1 PF00995.23 CBZ34858.1 - 2.1e-84 284.8 0.0 2.4e-84 284.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family ATP-synt_F PF01990.17 CBZ34858.1 - 0.025 14.9 0.1 2.1 8.7 0.0 3.2 3 0 0 3 3 3 0 ATP synthase (F/14-kDa) subunit H2O2_YaaD PF03883.14 CBZ34858.1 - 0.14 11.6 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Peroxide stress protein YaaA DnaJ PF00226.31 CBZ34859.1 - 1.3e-23 82.9 3.3 2.7e-23 81.9 3.3 1.6 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 CBZ34859.1 - 7.7e-10 38.8 6.2 1.5e-09 37.9 6.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CBZ34859.1 - 9.1e-08 32.2 3.3 1.7e-07 31.4 3.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBZ34859.1 - 5.9e-05 23.3 0.5 0.00017 21.9 0.1 1.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CBZ34859.1 - 0.011 16.5 1.2 0.03 15.2 0.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger AKAP95 PF04988.12 CBZ34859.1 - 0.037 14.3 0.3 0.037 14.3 0.3 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) DUF4136 PF13590.6 CBZ34859.1 - 0.049 14.2 3.4 0.12 13.0 3.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) zf-C2H2 PF00096.26 CBZ34859.1 - 0.059 13.8 1.5 0.12 12.9 1.5 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CBZ34859.1 - 0.19 11.7 1.1 0.4 10.7 1.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger ParcG PF10274.9 CBZ34860.1 - 8.4e-79 263.9 0.0 1e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 CBZ34860.1 - 0.26 10.9 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 PCI PF01399.27 CBZ34861.1 - 1.7e-06 28.5 0.1 4.4e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.6 CBZ34861.1 - 0.38 11.4 10.5 20 5.9 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4211 PF13926.6 CBZ34862.1 - 0.0096 16.0 0.9 0.018 15.1 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) DUF4004 PF13171.6 CBZ34862.1 - 0.019 15.2 0.1 0.019 15.2 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4004) Nre_N PF04894.12 CBZ34862.1 - 0.035 13.9 0.1 0.065 13.0 0.1 1.4 1 0 0 1 1 1 0 Archaeal Nre, N-terminal Gp-FAR-1 PF05823.12 CBZ34862.1 - 0.037 14.4 1.2 0.13 12.6 0.4 2.1 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SOAR PF16533.5 CBZ34862.1 - 0.38 10.8 6.6 1.5 8.9 0.8 2.8 2 0 0 2 2 2 0 STIM1 Orai1-activating region DUF913 PF06025.12 CBZ34862.1 - 1.3 7.9 0.0 1.3 7.9 0.0 3.2 2 1 1 3 3 3 0 Domain of Unknown Function (DUF913) Fib_alpha PF08702.10 CBZ34862.1 - 1.9 8.7 8.3 1.9 8.7 2.7 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Remorin_C PF03763.13 CBZ34862.1 - 3.5 7.6 10.6 0.78 9.6 3.9 3.0 2 1 0 2 2 2 0 Remorin, C-terminal region Pex2_Pex12 PF04757.14 CBZ34863.1 - 1.9e-27 96.4 11.5 2.3e-27 96.1 11.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 CBZ34863.1 - 0.02 14.7 12.1 0.033 14.1 12.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ34863.1 - 0.12 12.6 10.8 0.21 11.7 10.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CBZ34863.1 - 0.13 12.2 13.5 0.19 11.6 13.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TFIIS_C PF01096.18 CBZ34863.1 - 0.26 11.1 5.8 0.64 9.9 5.8 1.6 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) zf-RING_5 PF14634.6 CBZ34863.1 - 0.55 10.2 12.0 0.89 9.6 12.0 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBZ34863.1 - 0.58 10.2 9.0 1.1 9.4 9.0 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ34863.1 - 0.81 9.6 7.1 1.8 8.4 7.1 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ34863.1 - 1.2 9.5 10.2 2.2 8.7 10.2 1.4 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 CBZ34864.1 - 9.6e-06 25.4 16.1 2.4e-05 24.1 7.9 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 CBZ34864.1 - 0.0026 17.4 4.9 0.019 14.6 0.7 2.3 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 CBZ34864.1 - 4 7.6 9.7 42 4.3 9.8 2.3 1 1 1 2 2 2 0 PHD-finger Jas PF16135.5 CBZ34865.1 - 0.071 13.3 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling DUF4235 PF14019.6 CBZ34866.1 - 0.13 12.3 0.4 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) DHHC PF01529.20 CBZ34869.1 - 6.3e-36 123.4 2.7 6.3e-36 123.4 2.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF975 PF06161.11 CBZ34869.1 - 0.062 13.1 0.2 0.062 13.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF975) Yip1 PF04893.17 CBZ34869.1 - 0.34 10.6 11.3 0.054 13.2 0.8 2.2 2 0 0 2 2 2 0 Yip1 domain Pex2_Pex12 PF04757.14 CBZ34870.1 - 1.2e-13 51.2 0.1 5.2e-06 26.2 0.0 2.1 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 CBZ34870.1 - 4e-09 36.7 12.7 6.7e-09 35.9 12.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBZ34870.1 - 5.7e-09 35.7 10.9 8.5e-09 35.1 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ34870.1 - 1.7e-07 31.1 10.4 3.1e-07 30.2 10.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CBZ34870.1 - 1.3e-06 28.1 11.0 2.1e-06 27.5 11.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBZ34870.1 - 1.6e-06 27.9 12.5 2.7e-06 27.1 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ34870.1 - 9.8e-06 25.6 11.7 1.8e-05 24.8 11.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBZ34870.1 - 1.1e-05 25.6 9.1 2e-05 24.8 9.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ34870.1 - 2.9e-05 24.0 6.0 4.9e-05 23.3 6.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CBZ34870.1 - 0.00019 21.2 12.2 0.00033 20.4 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ34870.1 - 0.0003 20.7 8.6 0.0013 18.7 8.7 2.0 1 1 1 2 2 2 1 RING-type zinc-finger DUF4381 PF14316.6 CBZ34870.1 - 0.066 13.4 0.0 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) U-box PF04564.15 CBZ34870.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 U-box domain zf-Di19 PF05605.12 CBZ34870.1 - 0.24 11.7 2.9 0.37 11.1 0.2 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Nse PF11789.8 CBZ34870.1 - 0.78 9.6 4.9 1.9 8.4 4.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 CBZ34870.1 - 1.1 8.9 8.3 2.6 7.7 8.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 CBZ34870.1 - 1.7 8.8 6.7 3.3 7.9 6.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 IBR PF01485.21 CBZ34870.1 - 2.7 8.3 10.0 2 8.7 7.8 1.9 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 CBZ34870.1 - 4.2 7.2 11.2 1.2 9.0 7.9 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain LRR_4 PF12799.7 CBZ34871.1 - 3.1e-07 30.6 4.5 9e-05 22.8 2.9 3.3 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.6 CBZ34871.1 - 1.1e-06 29.0 0.3 6.3e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair LRR_8 PF13855.6 CBZ34871.1 - 4.3e-06 26.4 1.9 4.3e-06 26.4 1.9 2.3 2 0 0 2 2 2 1 Leucine rich repeat EF-hand_1 PF00036.32 CBZ34871.1 - 6.5e-05 22.2 0.1 0.0027 17.1 0.0 3.0 3 0 0 3 3 3 1 EF hand LRR_6 PF13516.6 CBZ34871.1 - 0.00046 20.0 1.7 0.78 9.9 0.0 3.1 3 0 0 3 3 2 2 Leucine Rich repeat EF-hand_6 PF13405.6 CBZ34871.1 - 0.00086 19.0 0.1 0.011 15.7 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 CBZ34871.1 - 0.0026 17.6 0.1 0.47 10.3 0.0 2.8 1 1 1 2 2 2 1 EF-hand domain pair 7TMR-HDED PF07697.11 CBZ34871.1 - 0.033 14.3 0.1 0.24 11.5 0.1 2.3 1 1 0 1 1 1 0 7TM-HD extracellular REV1_C PF16727.5 CBZ34871.1 - 0.042 14.2 0.6 0.18 12.2 0.1 2.4 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain LRR_1 PF00560.33 CBZ34871.1 - 0.052 14.1 3.3 3.4 8.6 0.1 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat Xpo1 PF08389.12 CBZ34871.1 - 0.19 11.8 1.3 1.8 8.6 0.0 2.8 3 1 0 3 3 3 0 Exportin 1-like protein DUF4352 PF11611.8 CBZ34872.1 - 0.01 16.1 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4352) SPC12 PF06645.13 CBZ34873.1 - 2.4e-07 30.7 0.8 3.3e-07 30.3 0.8 1.2 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) COX14 PF14880.6 CBZ34873.1 - 0.0078 16.0 0.0 0.022 14.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome oxidase c assembly Sensor PF13796.6 CBZ34873.1 - 0.057 13.5 4.6 0.093 12.8 4.6 1.3 1 0 0 1 1 1 0 Putative sensor FA_desaturase PF00487.24 CBZ34873.1 - 0.06 13.2 0.8 0.074 12.9 0.8 1.2 1 0 0 1 1 1 0 Fatty acid desaturase VPS9 PF02204.18 CBZ34874.1 - 4.4e-15 55.8 0.0 6.7e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MORN PF02493.20 CBZ34874.1 - 4.2e-09 35.8 20.8 5.7e-06 25.9 0.5 6.0 6 0 0 6 6 6 4 MORN repeat Pkinase PF00069.25 CBZ34875.1 - 7.1e-67 225.5 0.0 9.3e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34875.1 - 1.4e-38 132.7 0.0 1.8e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ34875.1 - 2.8e-05 23.6 0.0 5.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ34875.1 - 0.0059 16.6 0.0 0.17 11.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ34875.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CHAD PF05235.14 CBZ34876.1 - 0.098 12.6 7.0 0.19 11.7 7.0 1.5 1 1 0 1 1 1 0 CHAD domain TEX15 PF15326.6 CBZ34876.1 - 0.15 11.8 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Testis expressed sequence 15 Carot_N PF09150.10 CBZ34877.1 - 0.099 12.5 0.3 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 Orange carotenoid protein, N-terminal ADK PF00406.22 CBZ34878.1 - 8.3e-37 126.6 0.0 9.8e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ34878.1 - 4.2e-18 66.1 0.0 6.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CBZ34878.1 - 1.7e-10 40.7 2.6 2.7e-10 40.1 2.6 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid A2L_zn_ribbon PF08792.10 CBZ34878.1 - 0.0016 18.1 0.9 0.35 10.6 0.0 2.4 2 0 0 2 2 2 2 A2L zinc ribbon domain YadA_anchor PF03895.15 CBZ34878.1 - 0.0037 17.3 0.1 0.0068 16.5 0.1 1.3 1 0 0 1 1 1 1 YadA-like membrane anchor domain AAA_18 PF13238.6 CBZ34878.1 - 0.017 15.7 0.0 0.024 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBZ34878.1 - 0.017 15.2 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain TerY_C PF15616.6 CBZ34878.1 - 0.069 13.3 0.1 0.099 12.7 0.1 1.2 1 0 0 1 1 1 0 TerY-C metal binding domain zf-C2H2_3 PF13878.6 CBZ34878.1 - 0.18 11.6 2.1 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DUF2627 PF11118.8 CBZ34879.1 - 0.094 13.3 0.2 0.13 12.8 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2627) GSP_synth PF03738.14 CBZ34880.1 - 2.2e-46 158.8 0.0 7e-38 130.8 0.0 2.1 2 0 0 2 2 2 2 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 CBZ34880.1 - 2e-13 50.7 0.0 4.2e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 CHAP domain Arv1 PF04161.13 CBZ34881.1 - 4.8e-31 108.6 10.4 8.4e-31 107.8 10.4 1.4 1 1 0 1 1 1 1 Arv1-like family PH_12 PF16457.5 CBZ34882.1 - 5.3e-06 27.0 0.1 0.00026 21.5 0.0 3.5 3 0 0 3 3 3 1 Pleckstrin homology domain Creatinase_N_2 PF16189.5 CBZ34884.1 - 5.9e-16 59.0 0.0 8.5e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain LEF-9 PF05094.12 CBZ34884.1 - 0.16 10.5 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 9 (LEF-9) PfkB PF00294.24 CBZ34886.1 - 1.2e-36 126.5 0.1 1.6e-36 126.2 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase CENP-T_C PF15511.6 CBZ34887.1 - 6.8e-07 29.4 0.1 1e-06 28.8 0.0 1.2 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBZ34887.1 - 3.7e-05 23.9 0.1 5.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CBZ34887.1 - 0.0002 21.5 0.1 0.0003 20.9 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CBZ34887.1 - 0.00066 19.6 0.0 0.00082 19.3 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ34887.1 - 0.003 17.9 2.5 0.0058 17.0 2.5 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ34887.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_S17e PF00833.18 CBZ34887.1 - 0.045 13.7 0.6 0.054 13.4 0.6 1.1 1 0 0 1 1 1 0 Ribosomal S17 Ly-6_related PF06579.12 CBZ34887.1 - 0.071 13.4 0.6 0.088 13.1 0.6 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein DUF4400 PF14348.6 CBZ34887.1 - 0.09 12.3 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) PCP_red PF08369.10 CBZ34887.1 - 0.17 12.2 2.1 0.2 11.9 0.4 2.1 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit LSM PF01423.22 CBZ34889.1 - 9.6e-14 50.8 0.2 1.3e-13 50.4 0.2 1.3 1 0 0 1 1 1 1 LSM domain DUF2642 PF10842.8 CBZ34889.1 - 0.12 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) HydF_dimer PF18128.1 CBZ34889.1 - 0.16 12.1 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain Brix PF04427.18 CBZ34890.1 - 1.2e-29 103.8 0.0 1.6e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Brix domain Glyoxalase_4 PF13669.6 CBZ34891.1 - 2.6e-16 59.8 0.0 3.3e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 CBZ34891.1 - 0.00072 19.7 0.0 0.00086 19.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CBZ34891.1 - 0.0066 16.6 0.0 0.0078 16.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain PTH2 PF01981.16 CBZ34891.1 - 0.14 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 GDC-P PF02347.16 CBZ34892.1 - 2e-171 570.6 0.0 5.4e-157 523.0 0.1 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 CBZ34892.1 - 0.0036 16.6 0.1 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Beta-eliminating lyase Pkinase PF00069.25 CBZ34893.1 - 2.2e-56 191.2 0.0 2.4e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34893.1 - 9.1e-22 77.6 0.0 1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBZ34893.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CBZ34893.1 - 0.02 14.2 0.0 0.066 12.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Rhomboid PF01694.22 CBZ34900.1 - 0.0014 18.6 3.3 0.0045 17.0 3.3 1.8 1 1 0 1 1 1 1 Rhomboid family Pribosyltran PF00156.27 CBZ34901.1 - 1.3e-18 67.1 0.0 1.7e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBZ34901.1 - 3.7e-05 23.3 0.0 4.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 CBZ34901.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosyl transferase MCM_bind PF09739.9 CBZ34902.1 - 1.6e-35 122.6 0.0 6.7e-35 120.6 0.0 1.8 1 1 0 1 1 1 1 Mini-chromosome maintenance replisome factor AAA_lid_2 PF17863.1 CBZ34902.1 - 0.42 10.5 4.7 0.19 11.6 0.6 2.4 2 0 0 2 2 2 0 AAA lid domain NIF PF03031.18 CBZ34903.1 - 1.2e-51 174.6 0.7 2e-51 173.8 0.2 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.7 CBZ34903.1 - 0.15 12.5 0.1 1.1 9.7 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Ribosomal_L30_N PF08079.12 CBZ34904.1 - 2.1e-16 59.9 14.2 2.5e-16 59.7 14.2 1.1 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain CDRT4 PF15213.6 CBZ34904.1 - 0.013 16.2 0.1 0.02 15.5 0.1 1.3 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Ribosomal_L30 PF00327.20 CBZ34905.1 - 2.8e-19 68.8 1.9 6.2e-19 67.6 1.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CBZ34905.1 - 8.3e-16 58.0 13.0 1.5e-15 57.2 13.0 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DUF2062 PF09835.9 CBZ34906.1 - 2e-05 24.5 7.7 2.4e-05 24.3 7.7 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2062) DUF1453 PF07301.11 CBZ34906.1 - 0.091 12.8 4.7 0.57 10.2 0.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1453) TMEM223 PF14640.6 CBZ34906.1 - 0.67 10.1 3.2 0.85 9.8 0.3 2.0 1 1 1 2 2 2 0 Transmembrane protein 223 NifU PF01106.17 CBZ34907.1 - 1.8e-25 88.8 0.2 4.7e-25 87.5 0.0 1.8 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.11 CBZ34907.1 - 6.5e-23 80.6 0.0 1.1e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal eRF1_1 PF03463.15 CBZ34908.1 - 8.9e-31 106.6 0.1 2e-30 105.4 0.0 1.6 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.15 CBZ34908.1 - 2.2e-16 60.4 0.1 3.5e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CBZ34908.1 - 2.3e-14 53.8 0.0 7.3e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 eRF1 domain 3 DUF334 PF03904.13 CBZ34908.1 - 0.024 14.2 0.2 0.038 13.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) SIR2 PF02146.17 CBZ34909.1 - 5.5e-58 195.8 0.0 7.4e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zinc_ribbon_4 PF13717.6 CBZ34909.1 - 0.005 16.7 1.7 0.015 15.2 0.2 2.3 2 0 0 2 2 2 1 zinc-ribbon domain LIDHydrolase PF10230.9 CBZ34910.1 - 4.7e-64 216.5 0.0 5.5e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 CBZ34910.1 - 5.6e-12 45.4 0.0 6.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ34910.1 - 5e-05 24.0 0.1 6.5e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBZ34910.1 - 0.0004 20.1 0.0 0.00053 19.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CBZ34910.1 - 0.0045 17.1 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 CBZ34910.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF1057 PF06342.12 CBZ34910.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) IF4E PF01652.18 CBZ34912.1 - 1.2e-12 47.9 0.0 1.5e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1834 PF08873.11 CBZ34914.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) MMR_HSR1 PF01926.23 CBZ34915.1 - 5.9e-44 148.8 0.0 8.3e-21 74.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ34915.1 - 3.7e-25 88.6 0.4 2.7e-12 46.6 0.0 3.9 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CBZ34915.1 - 4.8e-21 74.9 0.1 8.1e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 CBZ34915.1 - 2.1e-17 63.7 0.1 0.00085 19.4 0.0 4.3 3 1 1 4 4 4 3 Dynamin family AIG1 PF04548.16 CBZ34915.1 - 7.6e-15 54.8 0.1 1.7e-06 27.5 0.0 2.7 3 0 0 3 3 2 2 AIG1 family Roc PF08477.13 CBZ34915.1 - 1.4e-13 51.1 0.0 4.2e-06 27.0 0.0 3.2 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CBZ34915.1 - 4.4e-13 49.5 0.3 0.0025 17.8 0.0 4.3 2 1 2 4 4 4 3 RsgA GTPase KH_dom-like PF14714.6 CBZ34915.1 - 6e-13 48.9 0.3 1.4e-12 47.8 0.3 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SRPRB PF09439.10 CBZ34915.1 - 2e-11 43.7 0.0 9e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Ras PF00071.22 CBZ34915.1 - 9.1e-11 41.6 0.0 1.1e-06 28.3 0.1 2.7 2 1 0 2 2 2 2 Ras family MMR_HSR1_Xtn PF16897.5 CBZ34915.1 - 1.1e-06 28.7 0.0 0.0089 16.0 0.0 2.5 2 0 0 2 2 2 2 C-terminal region of MMR_HSR1 domain Septin PF00735.18 CBZ34915.1 - 1.5e-05 24.4 0.0 0.0092 15.3 0.0 2.4 2 0 0 2 2 2 2 Septin ABC_tran PF00005.27 CBZ34915.1 - 1.6e-05 25.5 0.0 0.29 11.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PduV-EutP PF10662.9 CBZ34915.1 - 3.3e-05 23.7 0.0 1.2 8.9 0.0 3.6 4 0 0 4 4 3 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CBZ34915.1 - 5e-05 22.9 0.9 0.13 11.8 0.3 3.7 3 1 1 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 CBZ34915.1 - 7.5e-05 22.3 0.8 0.059 12.8 0.1 3.4 2 2 0 2 2 2 1 ADP-ribosylation factor family TniB PF05621.11 CBZ34915.1 - 7.7e-05 22.2 0.0 0.011 15.1 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein IIGP PF05049.13 CBZ34915.1 - 0.00026 20.2 0.0 0.051 12.6 0.0 2.5 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) GBP PF02263.19 CBZ34915.1 - 0.0021 17.4 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain T2SSE PF00437.20 CBZ34915.1 - 0.0078 15.3 0.0 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.14 CBZ34915.1 - 0.009 15.9 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 CBZ34915.1 - 0.012 16.2 0.0 0.63 10.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBZ34915.1 - 0.014 15.2 0.0 6.8 6.5 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_21 PF13304.6 CBZ34915.1 - 0.022 14.6 0.0 3.6 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system G-alpha PF00503.20 CBZ34915.1 - 0.022 13.9 0.1 1.6 7.8 0.0 2.9 2 1 0 3 3 3 0 G-protein alpha subunit ATPase_2 PF01637.18 CBZ34915.1 - 0.042 13.7 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CBZ34915.1 - 0.046 14.2 0.1 18 5.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain CLP1_P PF16575.5 CBZ34915.1 - 0.051 13.4 0.6 24 4.6 0.0 3.5 2 1 1 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FtsK_SpoIIIE PF01580.18 CBZ34915.1 - 0.07 12.5 0.0 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.6 CBZ34915.1 - 0.088 13.1 0.0 6.5 7.0 0.0 3.1 4 0 0 4 4 3 0 AAA domain AAA_15 PF13175.6 CBZ34915.1 - 0.16 11.7 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain MIT PF04212.18 CBZ34916.1 - 0.081 13.0 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain NUDIX_2 PF13869.6 CBZ34917.1 - 2.3e-41 141.4 0.0 3.7e-40 137.5 0.0 2.5 1 1 0 1 1 1 1 Nucleotide hydrolase Peptidase_M1 PF01433.20 CBZ34918.1 - 2.3e-75 252.9 0.9 4.1e-75 252.1 0.4 1.7 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CBZ34918.1 - 4.4e-51 174.3 0.1 7.7e-51 173.5 0.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CBZ34918.1 - 7.9e-42 143.6 0.0 1.5e-41 142.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain 6PF2K PF01591.18 CBZ34919.1 - 4.1e-32 111.3 0.0 6.1e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CBZ34919.1 - 1e-15 57.9 0.0 2.1e-13 50.4 0.0 2.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ank_2 PF12796.7 CBZ34919.1 - 2.8e-12 47.1 0.0 1.2e-11 45.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBZ34919.1 - 7.4e-12 45.3 0.1 1.6e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CBZ34919.1 - 8.1e-10 39.0 0.0 4.1e-07 30.4 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ34919.1 - 2.5e-08 34.0 0.2 6.3e-05 23.2 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CBZ34919.1 - 2.9e-08 33.3 0.0 7.5e-06 25.9 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat AAA_33 PF13671.6 CBZ34919.1 - 2.7e-07 30.8 0.2 4.7e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CBZ34919.1 - 6.5e-05 22.5 0.1 0.00014 21.5 0.1 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_5 PF07728.14 CBZ34919.1 - 0.031 14.3 0.0 0.1 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 CBZ34919.1 - 0.14 12.1 0.1 0.52 10.2 0.0 2.0 3 0 0 3 3 3 0 Adenylylsulphate kinase THF_DHG_CYH_C PF02882.19 CBZ34920.1 - 3.9e-61 205.1 0.2 5.6e-61 204.5 0.2 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CBZ34920.1 - 1.1e-36 125.6 0.3 1.6e-36 125.1 0.3 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Cyclin_N PF00134.23 CBZ34921.1 - 7.1e-15 54.9 0.7 5e-14 52.1 0.0 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBZ34921.1 - 0.0009 19.3 3.5 0.0019 18.3 1.1 2.6 2 1 0 2 2 2 1 Cyclin, C-terminal domain IU_nuc_hydro PF01156.19 CBZ34922.1 - 1.7e-18 67.2 1.5 2.5e-18 66.7 1.5 1.3 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Vps52 PF04129.12 CBZ34923.1 - 1.3e-47 162.8 0.0 2e-16 59.8 0.0 3.6 3 1 0 3 3 3 3 Vps52 / Sac2 family DASH_Duo1 PF08651.10 CBZ34923.1 - 0.00091 19.0 0.1 0.087 12.6 0.2 2.7 2 0 0 2 2 2 2 DASH complex subunit Duo1 TPR_2 PF07719.17 CBZ34925.1 - 4.8e-29 98.1 38.9 0.0012 18.8 0.1 15.1 16 0 0 16 16 15 7 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ34925.1 - 2.9e-23 80.6 24.5 0.00041 20.1 0.0 12.1 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ34925.1 - 5.7e-21 72.9 15.1 0.0075 16.4 0.0 13.2 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ34925.1 - 2.3e-18 66.2 54.2 0.00042 20.5 1.8 11.8 9 1 2 11 11 11 7 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ34925.1 - 3.8e-17 62.2 51.0 0.012 15.8 0.6 10.7 6 2 4 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ34925.1 - 1.5e-16 60.7 65.1 0.0015 19.1 6.7 11.7 8 3 4 12 12 12 7 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ34925.1 - 3.8e-11 42.5 10.5 0.0011 18.5 0.0 8.0 9 0 0 9 9 8 2 TPR repeat TPR_19 PF14559.6 CBZ34925.1 - 5.5e-09 36.4 29.3 0.00084 19.8 0.0 8.5 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ34925.1 - 0.00049 20.3 15.5 7.6 7.2 0.0 7.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ34925.1 - 0.00082 20.0 54.8 0.57 11.2 0.3 11.8 12 1 1 13 13 12 4 Tetratricopeptide repeat NARP1 PF12569.8 CBZ34925.1 - 0.0025 16.8 0.5 0.9 8.4 0.0 3.7 5 0 0 5 5 5 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 CBZ34925.1 - 0.0026 18.3 27.9 44 5.0 0.1 10.9 12 0 0 12 12 11 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CBZ34925.1 - 0.0077 16.3 11.2 9.5 6.4 0.0 6.2 5 2 1 6 6 6 1 Anaphase-promoting complex subunit 5 SHNi-TPR PF10516.9 CBZ34925.1 - 0.016 14.6 0.9 0.89 9.1 0.0 4.1 4 0 0 4 4 4 0 SHNi-TPR ANAPC3 PF12895.7 CBZ34925.1 - 0.071 13.3 21.0 3.7 7.8 0.3 7.7 4 2 6 10 10 10 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CBZ34925.1 - 0.2 11.7 9.4 0.58 10.3 0.0 4.9 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CBZ34925.1 - 0.33 10.9 48.0 2.8 8.0 0.3 10.6 12 0 0 12 12 11 0 Tetratricopeptide repeat Ist1 PF03398.14 CBZ34926.1 - 6.4e-45 153.0 0.2 7.9e-45 152.7 0.2 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ribosomal_S16 PF00886.19 CBZ34926.1 - 0.15 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S16 Ret2_MD PF18528.1 CBZ34927.1 - 1.6e-48 163.0 0.5 2.8e-48 162.2 0.5 1.4 1 0 0 1 1 1 1 RNA editing 3' terminal uridylyl transferase 2 middle domain PAP_assoc PF03828.19 CBZ34927.1 - 3.3e-15 56.0 0.1 7e-15 55.0 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBZ34927.1 - 7.5e-05 22.9 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2967 PF11179.8 CBZ34927.1 - 0.027 12.6 0.0 0.027 12.6 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2967) Polbeta PF18765.1 CBZ34927.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase 2OG-FeII_Oxy_2 PF13532.6 CBZ34928.1 - 1.7e-11 44.7 0.0 3.3e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1091 PF06477.13 CBZ34929.1 - 0.019 15.4 0.0 0.029 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) zf-B_box PF00643.24 CBZ34929.1 - 0.057 13.6 11.0 0.29 11.3 5.3 3.0 3 0 0 3 3 3 0 B-box zinc finger DUF3090 PF11290.8 CBZ34929.1 - 0.15 11.9 0.0 0.15 11.9 0.0 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3090) PyrI_C PF02748.15 CBZ34929.1 - 0.69 9.9 11.1 2.7 7.9 0.0 3.3 3 1 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Sgf11 PF08209.11 CBZ34929.1 - 1.3 8.7 10.1 0.59 9.7 0.4 2.8 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Cys_rich_KTR PF14205.6 CBZ34929.1 - 2.5 8.0 10.1 7.1 6.5 0.1 2.8 2 1 1 3 3 3 0 Cysteine-rich KTR PseudoU_synth_1 PF01416.20 CBZ34930.1 - 0.00023 21.6 0.0 0.031 14.7 0.0 2.9 2 1 0 2 2 2 2 tRNA pseudouridine synthase ParA PF10609.9 CBZ34931.1 - 2.3e-93 312.2 0.3 4.3e-92 308.0 0.3 2.0 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CBZ34931.1 - 6.6e-11 42.4 0.0 1.9e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CBZ34931.1 - 2.6e-07 30.7 0.2 2.5e-05 24.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 CBZ34931.1 - 4.5e-07 29.3 0.2 6.3e-06 25.6 0.1 2.5 3 0 0 3 3 3 1 Anion-transporting ATPase MipZ PF09140.11 CBZ34931.1 - 7.4e-05 22.2 0.1 0.0013 18.1 0.1 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_25 PF13481.6 CBZ34931.1 - 0.00011 21.9 0.5 0.00041 20.0 0.2 1.9 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 CBZ34931.1 - 0.004 16.6 0.0 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NACHT PF05729.12 CBZ34931.1 - 0.0077 16.2 0.2 0.014 15.4 0.2 1.4 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 CBZ34931.1 - 0.023 13.9 0.2 0.048 12.8 0.2 1.4 1 0 0 1 1 1 0 NB-ARC domain CLP1_P PF16575.5 CBZ34931.1 - 0.037 13.8 0.0 2.3 8.0 0.0 2.5 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 CBZ34931.1 - 0.039 13.8 0.0 0.067 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase CBP_BcsQ PF06564.12 CBZ34931.1 - 0.082 12.4 0.1 0.17 11.4 0.1 1.5 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Hpr_kinase_C PF07475.12 CBZ34931.1 - 0.094 12.2 0.1 0.41 10.1 0.2 1.9 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 CBZ34931.1 - 0.16 12.4 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 CBZ34931.1 - 0.16 11.8 0.2 0.38 10.6 0.2 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF1358 PF07096.11 CBZ34932.1 - 0.002 18.1 0.1 0.0043 17.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1358) TMEM108 PF15759.5 CBZ34932.1 - 0.012 14.7 7.1 0.017 14.2 7.1 1.2 1 0 0 1 1 1 0 TMEM108 family Metaviral_G PF09595.10 CBZ34932.1 - 3.9 7.5 12.9 0.64 10.1 8.5 1.8 2 0 0 2 2 2 0 Metaviral_G glycoprotein DUF2474 PF10617.9 CBZ34935.1 - 0.048 13.5 0.3 0.13 12.1 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) GGDEF_2 PF17853.1 CBZ34935.1 - 0.53 10.6 17.4 8.9 6.6 0.2 5.4 4 2 0 4 4 4 0 GGDEF-like domain ATP_bind_1 PF03029.17 CBZ34936.1 - 4.3e-48 164.2 0.0 4.4e-46 157.6 0.0 2.3 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 CBZ34936.1 - 0.0045 17.3 0.0 0.13 12.5 0.0 2.8 3 1 1 4 4 4 1 AAA domain AAA_18 PF13238.6 CBZ34936.1 - 0.018 15.6 2.7 0.11 13.0 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ34936.1 - 0.021 15.0 0.0 0.06 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CBZ34936.1 - 0.022 15.2 1.1 0.44 11.0 0.3 2.7 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 CBZ34936.1 - 0.068 13.6 0.0 0.57 10.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CBZ34936.1 - 0.077 12.7 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain PAP_assoc PF03828.19 CBZ34937.1 - 2.9e-07 30.6 0.0 6.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBZ34937.1 - 0.075 13.3 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain LRR_6 PF13516.6 CBZ34938.1 - 8.6e-35 115.8 20.7 0.00029 20.7 0.0 12.1 12 0 0 12 12 12 10 Leucine Rich repeat LRR_4 PF12799.7 CBZ34938.1 - 2.3e-05 24.7 19.8 0.61 10.6 0.1 6.6 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ34938.1 - 6.4e-05 23.0 8.1 14 6.7 0.1 8.0 10 0 0 10 10 10 1 Leucine Rich Repeat LRR_8 PF13855.6 CBZ34938.1 - 0.0011 18.7 18.9 2.5 7.9 1.4 7.5 3 2 2 5 5 5 3 Leucine rich repeat HrcA_DNA-bdg PF03444.15 CBZ34938.1 - 0.2 11.3 1.1 2.1 8.0 0.1 3.1 3 1 0 4 4 4 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Glycos_transf_2 PF00535.26 CBZ34941.1 - 0.045 13.6 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 MAPKK1_Int PF08923.10 CBZ34943.1 - 0.0016 18.2 0.0 0.049 13.5 0.0 2.0 2 0 0 2 2 2 2 Mitogen-activated protein kinase kinase 1 interacting DUF525 PF04379.14 CBZ34944.1 - 2.2e-15 56.7 0.0 5.5e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 ApaG domain Taxilin PF09728.9 CBZ34946.1 - 3e-10 39.8 46.0 3.9e-10 39.4 46.0 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein BRE1 PF08647.11 CBZ34946.1 - 0.0021 18.1 6.2 0.0021 18.1 6.2 4.4 1 1 3 4 4 4 1 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 CBZ34946.1 - 0.0084 16.3 27.4 0.3 11.3 7.6 3.0 1 1 0 2 2 2 2 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 CBZ34946.1 - 0.42 10.4 18.2 2.1 8.1 5.0 4.2 1 1 3 4 4 4 0 Hepatic lectin, N-terminal domain AAA_13 PF13166.6 CBZ34946.1 - 0.66 8.5 32.7 0.12 11.0 17.0 2.1 1 1 1 2 2 2 0 AAA domain Strep_SA_rep PF06696.11 CBZ34946.1 - 1.4 9.0 8.0 11 6.1 0.0 4.4 4 0 0 4 4 4 0 Streptococcal surface antigen repeat DUF1664 PF07889.12 CBZ34946.1 - 2 8.5 30.9 0.59 10.2 1.1 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 CBZ34946.1 - 4.5 7.4 49.0 0.3 11.2 15.2 4.1 1 1 1 3 3 3 0 Tropomyosin like GAS PF13851.6 CBZ34946.1 - 7.3 5.9 51.3 2.6 7.4 14.1 3.9 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 CBZ34946.1 - 8.3 6.6 51.0 3.2 8.0 24.7 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) PPR_2 PF13041.6 CBZ34947.1 - 3.3e-13 49.6 0.3 3.2e-06 27.2 0.0 3.8 2 1 1 3 3 3 3 PPR repeat family PPR_3 PF13812.6 CBZ34947.1 - 1.1e-10 41.4 0.0 3e-05 24.0 0.0 2.7 2 1 0 2 2 2 2 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ34947.1 - 6.3e-08 32.2 0.5 5.7e-07 29.1 0.6 2.1 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CBZ34947.1 - 2.9e-07 30.3 9.0 0.0035 17.5 0.1 5.1 5 1 0 5 5 5 2 PPR repeat DUF3368 PF11848.8 CBZ34947.1 - 0.0099 15.6 0.1 33 4.4 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) MNE1 PF13762.6 CBZ34947.1 - 0.22 11.5 0.1 1.3 9.0 0.0 2.2 2 1 1 3 3 3 0 Mitochondrial splicing apparatus component Cpn10 PF00166.21 CBZ34950.1 - 1.5e-24 85.8 0.3 1.7e-24 85.7 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF4821 PF16092.5 CBZ34951.1 - 1.5e-15 57.6 0.0 6.1e-15 55.6 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 CBZ34951.1 - 1.1e-07 31.4 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIRC PF00731.20 CBZ34951.1 - 0.024 14.2 1.1 7.8 6.1 0.0 3.5 3 0 0 3 3 3 0 AIR carboxylase Pyr_redox PF00070.27 CBZ34951.1 - 0.14 12.7 0.0 2.2 8.9 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 CBZ34952.1 - 6.1e-57 190.0 0.0 2e-27 95.2 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 CBZ34952.1 - 1.8e-19 70.4 0.1 4.3e-19 69.2 0.1 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 CBZ34952.1 - 2.8e-17 63.1 0.2 1.7e-07 31.7 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CBZ34952.1 - 6e-16 58.6 0.0 2e-07 30.7 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CBZ34952.1 - 4.2e-08 33.4 0.0 0.0015 18.8 0.1 3.8 2 2 2 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 CBZ34952.1 - 5.1e-08 32.9 0.1 0.0021 17.9 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 CBZ34952.1 - 5.4e-08 32.9 0.0 0.0071 16.2 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CBZ34952.1 - 6.7e-08 32.6 0.2 0.00037 20.6 0.0 2.8 2 1 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.10 CBZ34952.1 - 2.5e-05 24.0 0.1 0.024 14.4 0.1 2.4 2 0 0 2 2 2 2 Redoxin HyaE PF07449.11 CBZ34952.1 - 2.6e-05 24.1 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 CBZ34952.1 - 0.0026 17.5 0.1 1.3 8.7 0.0 3.6 2 2 2 4 4 4 1 Thioredoxin Glutaredoxin PF00462.24 CBZ34952.1 - 0.0095 16.1 0.1 0.48 10.7 0.0 2.8 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin_9 PF14595.6 CBZ34952.1 - 0.17 11.7 0.1 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin Thioredoxin PF00085.20 CBZ34953.1 - 7.1e-05 22.7 0.0 8.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF2012 PF09430.10 CBZ34954.1 - 2.8e-30 105.0 0.1 3.6e-30 104.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 CBZ34954.1 - 0.0044 17.3 0.2 0.015 15.5 0.1 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 CBZ34954.1 - 0.057 13.8 0.1 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 Prealbumin-like fold domain SNARE PF05739.19 CBZ34955.1 - 5.4e-09 35.9 1.4 5.4e-09 35.9 1.4 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.11 CBZ34955.1 - 0.0015 19.1 0.3 0.031 14.8 0.0 2.4 1 1 1 2 2 2 1 Syntaxin 6, N-terminal DHR10 PF18595.1 CBZ34955.1 - 0.0068 16.5 3.3 0.36 10.9 0.2 2.5 2 0 0 2 2 2 2 Designed helical repeat protein 10 domain eIF3_N PF09440.10 CBZ34955.1 - 0.049 14.1 2.0 0.49 10.8 0.4 2.3 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain T3SSipB PF16535.5 CBZ34955.1 - 0.075 13.5 3.8 0.44 11.0 0.2 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB CRPA PF05745.11 CBZ34955.1 - 0.096 12.7 0.2 0.18 11.8 0.2 1.5 1 0 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Laminin_II PF06009.12 CBZ34955.1 - 0.3 11.1 2.5 0.51 10.4 0.4 2.1 2 1 0 2 2 2 0 Laminin Domain II EMP24_GP25L PF01105.24 CBZ34955.1 - 0.52 10.2 4.5 0.11 12.4 0.5 1.8 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Snapin_Pallidin PF14712.6 CBZ34955.1 - 0.59 10.6 5.0 6.9 7.2 1.3 2.7 2 1 0 2 2 2 0 Snapin/Pallidin Spc7 PF08317.11 CBZ34955.1 - 0.72 8.7 5.1 1.7 7.4 0.5 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2951 PF11166.8 CBZ34955.1 - 1.6 9.0 5.4 0.35 11.1 1.6 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) Pentapeptide_4 PF13599.6 CBZ34956.1 - 2.7e-08 33.9 2.6 6e-07 29.5 0.1 3.8 3 1 1 4 4 4 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 CBZ34956.1 - 4.8e-07 29.3 5.4 4.5e-06 26.2 0.1 4.2 4 0 0 4 4 4 1 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 CBZ34956.1 - 0.00045 20.3 0.0 0.00045 20.3 0.0 4.3 4 0 0 4 4 4 1 Pentapeptide repeats (9 copies) DAGK_cat PF00781.24 CBZ34957.1 - 9.1e-12 44.7 0.1 1.5e-10 40.7 0.0 2.6 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain LGFP PF08310.11 CBZ34957.1 - 0.15 12.6 0.5 0.35 11.4 0.5 1.6 1 0 0 1 1 1 0 LGFP repeat RCC1 PF00415.18 CBZ34960.1 - 4.1e-71 235.4 44.3 1.3e-14 54.5 0.5 12.1 11 2 0 11 11 11 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ34960.1 - 9.3e-41 136.9 74.5 9.8e-08 31.6 1.1 11.8 13 0 0 13 13 13 9 Regulator of chromosome condensation (RCC1) repeat GAD-like PF08887.11 CBZ34960.1 - 0.0067 16.2 1.0 16 5.3 0.1 4.1 4 0 0 4 4 4 2 GAD-like domain Tachylectin PF14517.6 CBZ34960.1 - 0.012 15.1 0.2 0.06 12.9 0.1 2.0 2 0 0 2 2 2 0 Tachylectin Hira PF07569.11 CBZ34960.1 - 0.029 14.1 0.4 11 5.7 0.0 3.6 4 0 0 4 4 4 0 TUP1-like enhancer of split MliC PF09864.9 CBZ34960.1 - 0.15 12.0 0.7 14 5.8 0.2 3.0 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme RCC1 PF00415.18 CBZ34961.1 - 4e-66 219.4 32.1 7.7e-13 48.9 0.2 12.6 13 0 0 13 13 13 10 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ34961.1 - 1.2e-39 133.3 53.0 1.7e-05 24.5 0.7 12.0 11 0 0 11 11 11 11 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 CBZ34961.1 - 0.00087 19.1 0.2 0.17 11.6 0.0 3.6 4 1 0 4 4 4 1 TUP1-like enhancer of split DUF4213 PF13938.6 CBZ34961.1 - 0.85 9.9 7.6 1.8 8.9 0.5 4.6 4 1 1 5 5 5 0 Putative heavy-metal chelation RRM_1 PF00076.22 CBZ34962.1 - 6.7e-11 41.8 0.1 1e-10 41.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUA_3 PF17785.1 CBZ34962.1 - 0.04 13.7 0.1 1.9 8.3 0.0 2.4 1 1 1 2 2 2 0 PUA-like domain RRM_1 PF00076.22 CBZ34964.1 - 1.1e-08 34.8 0.1 1.6e-07 31.0 0.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GSHPx PF00255.19 CBZ34966.1 - 9.7e-37 124.9 0.3 1.2e-36 124.5 0.3 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CBZ34966.1 - 0.0049 16.8 0.1 0.01 15.7 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CBZ34966.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Redoxin AsnA PF03590.15 CBZ34967.1 - 5.7e-95 317.4 0.0 7.8e-95 316.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate-ammonia ligase tRNA-synt_2 PF00152.20 CBZ34967.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Exo_endo_phos PF03372.23 CBZ34970.1 - 2.2e-06 27.4 0.0 1.5e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family XRN_N PF03159.18 CBZ34970.1 - 0.00055 19.4 0.0 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus FYRC PF05965.14 CBZ34971.1 - 0.00065 19.8 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 CBZ34971.1 - 0.11 12.3 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 F/Y-rich N-terminus Zip PF02535.22 CBZ34971.1 - 3 7.0 5.4 1.4 8.1 2.1 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter TFIIA PF03153.13 CBZ34971.1 - 3 7.7 18.9 0.79 9.6 14.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CBZ34971.1 - 5.1 5.8 7.1 12 4.6 7.1 1.5 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 CBZ34971.1 - 6.3 5.5 10.4 11 4.7 10.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ribosomal_S9 PF00380.19 CBZ34972.1 - 4.6e-27 94.9 1.1 5.4e-27 94.7 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_S9 PF00380.19 CBZ34973.1 - 4.6e-27 94.9 1.1 5.4e-27 94.7 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 HSP70 PF00012.20 CBZ34974.1 - 7.5e-78 262.2 0.2 2.4e-41 141.6 0.0 2.8 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CBZ34974.1 - 0.00058 18.8 0.1 0.25 10.1 0.0 3.2 2 1 1 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 CBZ34974.1 - 0.12 12.8 0.0 3.2 8.2 0.0 3.1 2 2 0 2 2 2 0 Cell division protein FtsA HSP70 PF00012.20 CBZ34975.1 - 7.5e-78 262.2 0.2 2.4e-41 141.6 0.0 2.8 3 0 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 CBZ34975.1 - 0.00058 18.8 0.1 0.25 10.1 0.0 3.2 2 1 1 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 CBZ34975.1 - 0.12 12.8 0.0 3.2 8.2 0.0 3.1 2 2 0 2 2 2 0 Cell division protein FtsA OGFr_N PF04664.13 CBZ34976.1 - 2.1e-06 27.4 0.1 0.00058 19.4 0.0 2.2 2 0 0 2 2 2 2 Opioid growth factor receptor (OGFr) conserved region Glutaredoxin PF00462.24 CBZ34977.1 - 0.17 12.1 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin PIF1 PF05970.14 CBZ34978.1 - 1.4e-05 24.5 0.0 2.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase IstB_IS21 PF01695.17 CBZ34978.1 - 0.00017 21.4 0.2 0.0015 18.3 0.1 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein SRP54 PF00448.22 CBZ34978.1 - 0.0044 16.7 0.1 0.0094 15.6 0.0 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Bac_DnaA PF00308.18 CBZ34978.1 - 0.015 15.1 0.1 0.055 13.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein DUF815 PF05673.13 CBZ34978.1 - 0.029 13.5 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Viral_env_E26 PF11050.8 CBZ34978.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 AAA_30 PF13604.6 CBZ34978.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3395 PF11875.8 CBZ34979.1 - 1.5e-43 148.4 0.0 2.6e-43 147.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CBZ34979.1 - 1.3e-14 54.1 0.2 2.4e-14 53.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Mcp5_PH PF12814.7 CBZ34980.1 - 4.7e-25 88.1 1.1 7.6e-25 87.4 1.1 1.3 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology NMD3 PF04981.13 CBZ34982.1 - 3.2e-77 259.3 3.4 4.5e-77 258.8 3.4 1.2 1 0 0 1 1 1 1 NMD3 family FlgM PF04316.13 CBZ34982.1 - 2.9 8.3 5.0 0.72 10.3 0.7 2.3 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM TF_Zn_Ribbon PF08271.12 CBZ34982.1 - 3.6 7.2 9.7 0.6 9.7 1.2 3.0 2 1 0 2 2 2 0 TFIIB zinc-binding Pkinase PF00069.25 CBZ34983.1 - 8.3e-30 104.0 0.0 2.8e-29 102.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ34983.1 - 8.6e-12 44.9 0.0 6.5e-06 25.6 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CBZ34983.1 - 0.038 13.0 0.1 0.057 12.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PKD_channel PF08016.12 CBZ34984.1 - 2.8e-07 29.6 8.5 4.4e-07 28.9 8.5 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CBZ34984.1 - 0.00011 21.5 10.8 0.00011 21.5 10.8 1.8 2 0 0 2 2 2 1 Ion transport protein DUF4349 PF14257.6 CBZ34984.1 - 0.86 9.0 3.8 2 7.8 3.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) PRKCSH_1 PF13015.6 CBZ34985.1 - 9.8e-22 77.3 0.2 2.4e-21 76.0 0.2 1.7 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CBZ34985.1 - 8.8e-05 23.4 0.1 0.00031 21.7 0.1 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Imm6 PF14434.6 CBZ34985.1 - 0.0071 16.3 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Immunity protein Imm6 AAA_23 PF13476.6 CBZ34985.1 - 0.19 12.2 0.1 0.19 12.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain CENP-H PF05837.12 CBZ34985.1 - 0.84 10.1 10.2 0.66 10.4 3.0 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Spc24 PF08286.11 CBZ34985.1 - 6.8 7.0 7.1 24 5.3 1.3 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 AAA_6 PF12774.7 CBZ34988.1 - 8.9e-154 511.3 0.0 8.3e-153 508.1 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ34988.1 - 3.5e-114 382.0 11.0 3.5e-114 382.0 11.0 4.0 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ34988.1 - 5e-97 324.3 0.2 1.8e-96 322.5 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ34988.1 - 1e-95 320.6 0.1 8.8e-95 317.4 0.0 2.7 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ34988.1 - 2.8e-86 288.2 0.7 2.8e-86 288.2 0.7 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 CBZ34988.1 - 2.6e-53 181.3 8.1 4.9e-53 180.3 8.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 CBZ34988.1 - 5.2e-53 179.2 0.0 4.1e-49 166.6 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ34988.1 - 4.3e-51 173.0 0.0 1.2e-50 171.6 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ34988.1 - 1.2e-39 135.1 0.0 3.8e-37 127.0 0.0 3.9 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 CBZ34988.1 - 1.8e-23 83.0 0.0 4.7e-06 26.6 0.0 6.0 5 2 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CBZ34988.1 - 3.2e-18 66.0 0.1 1.1e-16 61.1 0.0 3.7 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBZ34988.1 - 8e-16 58.1 0.0 3.2e-15 56.2 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBZ34988.1 - 1.2e-06 29.0 10.8 1.5 9.1 0.0 7.8 6 1 1 7 7 6 2 AAA ATPase domain AAA PF00004.29 CBZ34988.1 - 4.6e-06 27.1 0.2 1.6 9.2 0.0 5.2 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ34988.1 - 5.3e-06 26.7 0.5 8.8 6.6 0.0 6.3 6 0 0 6 6 5 0 AAA domain FtsK_SpoIIIE PF01580.18 CBZ34988.1 - 1.2e-05 24.8 1.4 0.0029 17.0 0.0 3.7 4 0 0 4 4 4 1 FtsK/SpoIIIE family T2SSE PF00437.20 CBZ34988.1 - 0.0075 15.4 0.1 2.2 7.3 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein OHCU_decarbox PF09349.10 CBZ34988.1 - 0.011 16.2 2.5 0.038 14.5 0.5 3.1 2 0 0 2 2 2 0 OHCU decarboxylase AAA_18 PF13238.6 CBZ34988.1 - 0.014 15.9 0.0 24 5.5 0.0 4.9 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 CBZ34988.1 - 0.025 15.0 0.0 5.4 7.5 0.0 4.4 4 0 0 4 4 4 0 RNA helicase AAA_30 PF13604.6 CBZ34988.1 - 0.027 14.2 1.4 2.4 7.8 0.2 3.9 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 CBZ34988.1 - 4.2 7.4 7.9 0.31 11.1 0.4 3.1 3 0 0 3 3 2 0 Helicase HerA, central domain Peptidase_M28 PF04389.17 CBZ34990.1 - 0.00036 20.3 0.2 0.00072 19.3 0.2 1.5 1 0 0 1 1 1 1 Peptidase family M28 Fer2 PF00111.27 CBZ34991.1 - 5e-12 45.6 1.0 7.5e-12 45.0 1.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RRM_1 PF00076.22 CBZ34992.1 - 2.5e-07 30.4 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Btz PF09405.10 CBZ34992.1 - 0.0036 17.6 0.0 0.0066 16.7 0.0 1.5 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Nrap_D3 PF17404.2 CBZ34994.1 - 0.12 12.4 0.9 0.43 10.7 0.2 2.1 2 0 0 2 2 2 0 Nrap protein domain 3 TROVE PF05731.11 CBZ34997.1 - 1.9e-60 205.2 0.0 8.5e-31 107.5 0.0 2.4 2 0 0 2 2 2 2 TROVE domain WD40 PF00400.32 CBZ34997.1 - 2.3e-15 56.7 14.8 0.017 16.0 0.0 8.6 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF4062 PF13271.6 CBZ34997.1 - 5.4e-12 45.9 0.0 1.8e-11 44.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) ANAPC4_WD40 PF12894.7 CBZ34997.1 - 7.3e-06 26.2 0.3 3.3 8.1 0.0 5.3 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ34997.1 - 0.25 10.3 0.1 2.4 7.0 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ax_dynein_light PF10211.9 CBZ34998.1 - 4.5e-44 150.6 3.8 6.8e-44 150.1 3.8 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain AAA_33 PF13671.6 CBZ34998.1 - 0.062 13.5 0.1 0.062 13.5 0.1 2.1 2 1 0 2 2 2 0 AAA domain FapA PF03961.13 CBZ34998.1 - 0.26 9.8 2.2 0.39 9.3 2.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4570 PF15134.6 CBZ34998.1 - 0.38 10.8 4.3 0.77 9.8 3.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) PrpR_N PF06506.11 CBZ35000.1 - 0.012 15.2 0.3 0.04 13.5 0.1 1.9 2 0 0 2 2 2 0 Propionate catabolism activator HMD PF03201.16 CBZ35000.1 - 0.42 10.9 3.8 0.49 10.7 0.1 2.9 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase PseudoU_synth_2 PF00849.22 CBZ35002.1 - 7.9e-15 55.3 0.1 3.1e-07 30.6 0.0 3.8 2 2 0 2 2 2 2 RNA pseudouridylate synthase TT_ORF2 PF02957.15 CBZ35002.1 - 2.2 9.2 5.4 11 6.9 0.9 3.5 3 0 0 3 3 3 0 TT viral ORF2 zf-RING_2 PF13639.6 CBZ35003.1 - 1.1e-06 28.8 7.8 1e-05 25.8 1.4 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CBZ35003.1 - 2.2e-05 24.2 7.1 6.9e-05 22.6 1.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ35003.1 - 0.00043 20.1 4.6 0.0021 17.9 1.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CBZ35003.1 - 0.0018 18.1 1.6 0.0018 18.1 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CBZ35003.1 - 0.0048 16.6 2.1 0.48 10.2 0.0 2.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBZ35003.1 - 0.011 15.5 2.4 0.011 15.5 2.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ35003.1 - 0.013 15.5 1.6 0.013 15.5 1.6 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Spore_III_AB PF09548.10 CBZ35003.1 - 0.047 13.8 0.4 3 7.9 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Baculo_IE-1 PF05290.11 CBZ35003.1 - 0.1 12.6 0.3 0.1 12.6 0.3 1.6 2 0 0 2 2 1 0 Baculovirus immediate-early protein (IE-0) Snapin_Pallidin PF14712.6 CBZ35003.1 - 0.16 12.4 4.0 0.71 10.3 0.7 2.2 1 1 0 2 2 2 0 Snapin/Pallidin DHR10 PF18595.1 CBZ35003.1 - 0.17 12.0 0.2 0.17 12.0 0.2 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain GOLGA2L5 PF15070.6 CBZ35003.1 - 0.19 10.3 4.0 0.27 9.8 4.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 YscO PF07321.12 CBZ35003.1 - 1.3 8.9 9.7 5.9 6.8 2.3 2.4 2 0 0 2 2 2 0 Type III secretion protein YscO zf-RING_UBOX PF13445.6 CBZ35003.1 - 3.6 7.7 13.2 3.3 7.8 2.2 2.9 2 0 0 2 2 2 0 RING-type zinc-finger Ribosomal_60s PF00428.19 CBZ35004.1 - 0.064 13.9 0.4 0.064 13.9 0.4 6.7 7 1 0 7 7 7 0 60s Acidic ribosomal protein DnaJ PF00226.31 CBZ35006.1 - 9.7e-21 73.7 0.2 2.2e-20 72.5 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 CBZ35006.1 - 3.3e-05 23.4 0.2 0.00016 21.2 0.0 2.1 2 1 0 2 2 2 1 X-domain of DnaJ-containing Aldo_ket_red PF00248.21 CBZ35007.1 - 5.1e-27 94.8 0.0 4.2e-23 82.0 0.0 2.2 2 0 0 2 2 2 2 Aldo/keto reductase family LRR_4 PF12799.7 CBZ35008.1 - 1.3e-12 47.7 1.8 0.0001 22.6 0.2 4.2 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ35008.1 - 7.7e-12 44.8 2.7 0.0032 17.2 5.2 4.5 3 1 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 CBZ35008.1 - 0.00026 20.8 4.2 1.5 9.1 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_9 PF14580.6 CBZ35008.1 - 0.0021 17.6 0.0 0.011 15.3 0.0 2.0 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 CBZ35008.1 - 0.022 15.2 11.9 16 6.5 0.4 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat PTCB-BRCT PF12738.7 CBZ35009.1 - 1.8e-06 27.8 0.1 0.036 14.0 0.0 3.7 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 CBZ35009.1 - 0.005 17.2 0.0 7.7 7.0 0.0 3.6 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain HSP70 PF00012.20 CBZ35010.1 - 7.4e-243 807.1 3.7 8.5e-243 806.9 3.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ35010.1 - 6.7e-18 64.6 0.2 3.9e-16 58.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CBZ35010.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 CBZ35010.1 - 0.0093 15.5 0.4 4.6 6.7 0.0 2.6 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family DUF1464 PF07318.12 CBZ35010.1 - 0.032 13.4 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Hydantoinase_A PF01968.18 CBZ35010.1 - 0.13 11.5 2.6 0.073 12.3 0.3 1.9 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase FtsA PF14450.6 CBZ35010.1 - 0.51 10.8 4.7 6.5 7.2 0.1 3.3 3 3 0 3 3 3 0 Cell division protein FtsA FYVE PF01363.21 CBZ35012.1 - 3.7e-13 49.4 10.7 7.9e-13 48.3 5.2 2.7 2 0 0 2 2 2 2 FYVE zinc finger DnaJ PF00226.31 CBZ35013.1 - 5e-22 77.8 0.3 1.3e-21 76.5 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 CBZ35013.1 - 1.8e-09 37.3 0.0 1.4e-05 24.6 0.1 2.6 1 1 1 2 2 2 2 X-domain of DnaJ-containing GRAS PF03514.14 CBZ35013.1 - 0.072 12.0 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 GRAS domain family Cupin_8 PF13621.6 CBZ35015.1 - 4.2e-59 200.3 0.0 9.7e-58 195.9 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain CENP-B_dimeris PF09026.10 CBZ35015.1 - 0.069 13.5 2.2 0.2 12.1 2.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PHC2_SAM_assoc PF16616.5 CBZ35017.1 - 2.8 8.8 6.0 0.28 12.0 0.7 1.9 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DNA_ligase_OB_2 PF14743.6 CBZ35020.1 - 1.7e-18 66.3 0.0 4e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.6 CBZ35020.1 - 2.1e-12 47.2 1.8 2.1e-12 47.2 1.8 2.2 2 0 0 2 2 2 1 Probable Zinc-ribbon domain DNA_ligase_A_M PF01068.21 CBZ35020.1 - 8.1e-12 45.2 0.0 9.7e-05 22.1 0.0 3.0 2 1 0 3 3 3 2 ATP dependent DNA ligase domain PhnA_Zn_Ribbon PF08274.12 CBZ35020.1 - 0.013 15.4 2.7 1.1 9.3 1.3 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon mRNA_cap_enzyme PF01331.19 CBZ35020.1 - 0.13 12.1 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 CBZ35021.1 - 2.7e-19 69.6 0.0 1.1e-18 67.6 0.0 1.9 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB_2 PF14743.6 CBZ35021.1 - 2.6e-17 62.6 0.0 5.2e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 DNA ligase OB-like domain DUF4379 PF14311.6 CBZ35021.1 - 4.4e-06 27.0 0.7 1e-05 25.8 0.7 1.7 1 0 0 1 1 1 1 Probable Zinc-ribbon domain mRNA_cap_enzyme PF01331.19 CBZ35021.1 - 0.0027 17.6 0.1 5.2 6.9 0.1 3.3 2 2 1 3 3 3 2 mRNA capping enzyme, catalytic domain Zn-ribbon_8 PF09723.10 CBZ35021.1 - 0.0055 16.8 1.5 0.013 15.6 0.5 2.2 2 0 0 2 2 2 1 Zinc ribbon domain CCP_MauG PF03150.14 CBZ35021.1 - 0.098 13.3 0.0 0.21 12.2 0.0 1.5 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Zn_Tnp_IS1595 PF12760.7 CBZ35021.1 - 0.11 12.4 2.5 2.2 8.3 0.1 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Thioredoxin PF00085.20 CBZ35022.1 - 0.0062 16.5 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin MutS_IV PF05190.18 CBZ35022.1 - 0.094 13.1 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 MutS family domain IV MMR_HSR1 PF01926.23 CBZ35023.1 - 9.3e-15 54.7 0.0 4.4e-13 49.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ35023.1 - 4.7e-06 26.2 0.0 0.00013 21.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ35023.1 - 9.5e-05 22.4 0.0 0.0021 18.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CBZ35023.1 - 0.0055 16.3 0.0 3.7 7.0 0.1 2.9 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CBZ35023.1 - 2.9 7.9 9.3 0.27 11.3 0.2 2.8 2 1 1 3 3 3 0 Dynamin family DUF4266 PF14086.6 CBZ35023.1 - 5 8.2 9.7 28 5.8 5.8 3.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Prefoldin PF02996.17 CBZ35024.1 - 2.2e-26 92.1 2.0 2.9e-26 91.7 1.4 1.5 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 CBZ35024.1 - 0.018 15.0 3.8 0.88 9.6 0.2 2.5 2 1 0 2 2 2 0 Prefoldin subunit NBP1 PF08537.10 CBZ35024.1 - 0.02 14.3 1.7 0.067 12.6 1.7 1.7 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 End3 PF12761.7 CBZ35024.1 - 0.057 13.6 3.8 0.8 9.9 0.6 2.3 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 BST2 PF16716.5 CBZ35024.1 - 0.074 13.6 3.4 2.8 8.6 0.9 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 YabA PF06156.13 CBZ35024.1 - 3 8.5 5.7 19 6.0 3.0 2.3 2 0 0 2 2 2 0 Initiation control protein YabA WD40 PF00400.32 CBZ35026.1 - 6.5e-15 55.3 16.3 0.023 15.5 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat WWE PF02825.20 CBZ35026.1 - 1.6e-10 41.4 2.5 1.7e-10 41.4 0.5 2.2 2 1 0 2 2 2 1 WWE domain DnaJ PF00226.31 CBZ35027.1 - 2.1e-18 66.2 0.8 3.6e-18 65.4 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain MORN PF02493.20 CBZ35028.1 - 9.1e-46 151.1 127.1 0.00012 21.8 0.5 24.4 26 0 0 26 26 26 20 MORN repeat FYVE PF01363.21 CBZ35028.1 - 1.5e-27 95.5 12.9 2.4e-19 69.2 3.5 2.6 2 0 0 2 2 2 2 FYVE zinc finger zf-CRD PF17979.1 CBZ35028.1 - 0.17 12.0 8.6 3.5 7.7 2.6 2.6 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions FYVE_2 PF02318.16 CBZ35028.1 - 1.1 9.5 11.7 3.1 8.0 2.3 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger Cyt-b5 PF00173.28 CBZ35029.1 - 2.5e-18 66.0 0.0 5.1e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3474 PF11960.8 CBZ35029.1 - 0.0045 17.2 0.7 3.8 7.7 0.1 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF3474) zf-C2H2 PF00096.26 CBZ35031.1 - 0.13 12.7 0.2 0.45 11.1 0.2 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Shisa PF13908.6 CBZ35032.1 - 0.00043 20.6 1.0 0.0043 17.3 0.0 2.2 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator CYYR1 PF10873.8 CBZ35032.1 - 0.0025 18.3 1.4 0.0025 18.3 0.0 1.7 2 0 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 Neur_chan_memb PF02932.16 CBZ35032.1 - 0.038 14.1 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4803 PF16061.5 CBZ35032.1 - 0.2 11.1 2.2 12 5.2 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4803) EphA2_TM PF14575.6 CBZ35032.1 - 1.4 9.9 4.5 2.6 9.0 1.7 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Prenyltrans PF00432.21 CBZ35033.1 - 3.4e-23 81.1 12.1 2.6e-05 23.9 0.1 5.7 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat XPC-binding PF09280.11 CBZ35033.1 - 0.16 11.7 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 XPC-binding domain COG7 PF10191.9 CBZ35034.1 - 3.6e-10 38.8 6.8 0.0053 15.1 1.6 5.2 5 0 0 5 5 5 4 Golgi complex component 7 (COG7) MoCF_biosynth PF00994.24 CBZ35034.1 - 0.0038 16.9 0.1 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 Probable molybdopterin binding domain AIP3 PF03915.13 CBZ35034.1 - 0.14 11.2 2.0 2.1 7.4 0.1 2.4 2 1 0 2 2 2 0 Actin interacting protein 3 V_ATPase_I PF01496.19 CBZ35034.1 - 0.47 8.3 1.7 0.84 7.5 0.1 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2497 PF10691.9 CBZ35034.1 - 0.77 10.2 4.6 32 5.0 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2497) DUF445 PF04286.12 CBZ35034.1 - 0.94 9.2 3.1 8.5 6.1 0.0 3.3 3 2 0 3 3 3 0 Protein of unknown function (DUF445) PhoD PF09423.10 CBZ35035.1 - 2.2e-05 23.6 0.0 0.00075 18.6 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Tad PF13400.6 CBZ35035.1 - 1 9.7 7.5 0.88 9.9 1.5 2.5 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Abhydrolase_6 PF12697.7 CBZ35038.1 - 4.2e-14 53.7 0.0 7.7e-14 52.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBZ35038.1 - 6.8e-05 22.2 2.5 0.083 12.1 0.1 3.9 3 1 0 3 3 3 2 Serine aminopeptidase, S33 DUF915 PF06028.11 CBZ35038.1 - 0.0021 17.5 0.0 0.0048 16.3 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 CBZ35038.1 - 0.052 13.2 2.1 0.29 10.7 1.1 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold RRM_1 PF00076.22 CBZ35039.1 - 3.8e-16 58.7 0.0 6.6e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ35039.1 - 1.4e-05 24.7 0.0 2.9e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ35039.1 - 0.0029 17.7 0.0 0.0078 16.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif PHM7_cyt PF14703.6 CBZ35039.1 - 0.075 13.3 0.1 1.6 9.0 0.1 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Glutaredoxin PF00462.24 CBZ35040.1 - 6.7e-06 26.2 0.0 2.1e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 CBZ35040.1 - 5.5e-05 23.5 0.0 0.00019 21.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_4 PF14834.6 CBZ35040.1 - 0.016 15.6 0.0 0.031 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CBZ35040.1 - 0.12 12.7 0.0 0.42 11.0 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF3918 PF13056.6 CBZ35040.1 - 0.23 11.1 0.2 0.48 10.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) 3HCDH_N PF02737.18 CBZ35041.1 - 2.6e-50 170.8 4.1 4.9e-50 169.9 4.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CBZ35041.1 - 1.3e-35 121.9 0.5 6.2e-23 81.2 0.0 3.1 4 0 0 4 4 4 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_1 PF00378.20 CBZ35041.1 - 9.2e-29 100.5 0.2 9.2e-29 100.5 0.2 2.2 2 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ35041.1 - 2.4e-19 70.0 0.2 5.2e-19 68.9 0.1 1.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase NAD_binding_2 PF03446.15 CBZ35041.1 - 7.2e-05 23.0 1.4 0.00027 21.2 1.4 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CBZ35041.1 - 0.0099 16.4 1.4 0.037 14.6 1.4 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Penicillinase_R PF03965.16 CBZ35041.1 - 0.075 13.4 0.0 6.2 7.2 0.0 2.7 2 0 0 2 2 2 0 Penicillinase repressor Shikimate_DH PF01488.20 CBZ35041.1 - 0.13 12.3 1.3 0.6 10.2 0.2 2.4 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CBZ35041.1 - 0.18 12.1 2.5 0.28 11.4 0.6 2.4 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain SNF2_N PF00176.23 CBZ35042.1 - 1.3e-28 99.7 0.3 1.2e-18 67.0 0.0 3.1 3 0 0 3 3 3 3 SNF2 family N-terminal domain zf-RING_UBOX PF13445.6 CBZ35042.1 - 1.8e-06 27.9 1.6 8e-06 25.8 1.6 2.2 1 0 0 1 1 1 1 RING-type zinc-finger Helicase_C PF00271.31 CBZ35042.1 - 1e-05 25.9 0.0 1.9e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 CBZ35042.1 - 1.3e-05 25.4 4.7 1.3e-05 25.4 4.7 2.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CBZ35042.1 - 2.3e-05 24.1 4.5 8.7e-05 22.3 4.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBZ35042.1 - 2.6e-05 24.0 5.2 2.6e-05 24.0 5.2 3.7 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ35042.1 - 0.0001 22.2 4.6 0.0001 22.2 4.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain DEAD PF00270.29 CBZ35042.1 - 0.00018 21.3 0.0 0.00038 20.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 CBZ35042.1 - 0.00049 19.9 7.8 0.00049 19.9 7.8 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ35042.1 - 0.0013 18.8 9.9 0.0037 17.4 6.0 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBZ35042.1 - 0.0058 16.5 4.4 0.0058 16.5 4.4 3.0 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 Lar_restr_allev PF14354.6 CBZ35042.1 - 0.44 11.0 6.3 2 8.9 0.2 3.7 4 0 0 4 4 3 0 Restriction alleviation protein Lar Peptidase_M3 PF01432.20 CBZ35043.1 - 1.7e-115 386.9 0.0 1.3e-114 384.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 CBZ35043.1 - 0.038 13.6 0.4 0.07 12.8 0.4 1.4 1 0 0 1 1 1 0 Peptidase M50B-like PQQ_2 PF13360.6 CBZ35044.1 - 0.0039 16.8 0.4 0.015 14.9 0.1 2.1 3 0 0 3 3 3 1 PQQ-like domain U-box PF04564.15 CBZ35046.1 - 0.00064 19.8 0.0 0.0017 18.4 0.0 1.7 2 0 0 2 2 2 1 U-box domain Circo_capsid PF02443.15 CBZ35046.1 - 1.5 8.3 6.8 2.3 7.8 6.8 1.2 1 0 0 1 1 1 0 Circovirus capsid protein Pro_dh PF01619.18 CBZ35047.1 - 1.3e-64 218.6 0.4 2.3e-64 217.8 0.4 1.3 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 CBZ35047.1 - 0.0012 18.3 0.0 0.024 14.1 0.0 2.3 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel EF-hand_7 PF13499.6 CBZ35047.1 - 0.064 13.7 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair DUF1133 PF06576.11 CBZ35047.1 - 0.11 11.9 0.0 0.39 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) Equine_IAV_S2 PF06502.11 CBZ35047.1 - 0.15 12.2 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein CTP_transf_1 PF01148.20 CBZ35048.1 - 2e-62 211.4 17.5 2.9e-62 210.8 17.5 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosomal_S28e PF01200.18 CBZ35049.1 - 1.9e-29 101.4 0.8 2.4e-29 101.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e Ribosomal_S28e PF01200.18 CBZ35050.1 - 1.9e-29 101.4 0.8 2.4e-29 101.1 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S28e MIT PF04212.18 CBZ35051.1 - 8.3e-05 22.6 0.1 0.00017 21.6 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Spo0A_C PF08769.11 CBZ35051.1 - 0.06 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal FliS PF02561.14 CBZ35051.1 - 0.17 12.2 0.1 0.51 10.6 0.0 1.8 2 0 0 2 2 2 0 Flagellar protein FliS MIT PF04212.18 CBZ35052.1 - 8.3e-05 22.6 0.1 0.00017 21.6 0.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Spo0A_C PF08769.11 CBZ35052.1 - 0.06 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal FliS PF02561.14 CBZ35052.1 - 0.17 12.2 0.1 0.51 10.6 0.0 1.8 2 0 0 2 2 2 0 Flagellar protein FliS LRR_6 PF13516.6 CBZ35053.1 - 4.4e-05 23.2 8.6 3.7 7.9 0.0 6.2 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 CBZ35053.1 - 0.025 15.1 12.4 10 7.1 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.7 CBZ35053.1 - 0.32 11.5 10.4 53 4.4 0.1 5.1 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ35053.1 - 0.46 10.3 7.1 5.7 6.8 0.0 5.1 5 1 1 6 6 6 0 Leucine rich repeat Lipid_DES PF08557.10 CBZ35055.1 - 4.2e-15 54.9 0.4 5.9e-15 54.5 0.4 1.2 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 CBZ35056.1 - 1.2e-22 81.0 24.6 2e-22 80.3 24.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 CBZ35056.1 - 2.3e-14 52.6 0.5 4.6e-14 51.6 0.5 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Pkinase PF00069.25 CBZ35059.1 - 1.9e-58 197.9 0.0 2.9e-58 197.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35059.1 - 1.1e-35 123.2 0.0 1.7e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ35059.1 - 1.2e-06 28.1 0.0 0.00057 19.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like PAS PF00989.25 CBZ35059.1 - 1.7e-06 28.0 0.0 5.1e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold Pkinase_fungal PF17667.1 CBZ35059.1 - 1.9e-05 23.7 0.0 3.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ35059.1 - 0.00019 20.9 0.1 0.00056 19.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 CBZ35059.1 - 0.00097 19.4 0.0 0.0037 17.5 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 CBZ35059.1 - 0.0024 17.9 0.0 0.0093 16.0 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 CBZ35059.1 - 0.003 17.8 0.0 0.014 15.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_10 PF13596.6 CBZ35059.1 - 0.012 16.2 0.0 0.03 14.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain FTA2 PF13095.6 CBZ35059.1 - 0.038 13.6 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MLTR_LBD PF17765.1 CBZ35059.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain APH PF01636.23 CBZ35059.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ank_4 PF13637.6 CBZ35060.1 - 1.3e-08 35.2 8.0 0.028 15.0 0.1 5.9 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ35060.1 - 1.1e-06 29.1 0.4 0.2 12.3 0.0 4.4 4 1 1 5 5 5 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ35060.1 - 0.011 16.1 3.5 3.4 8.5 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeat TPR_14 PF13428.6 CBZ35061.1 - 3.6 8.7 9.4 0.84 10.6 1.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Na_trans_cytopl PF11933.8 CBZ35062.1 - 0.65 9.8 6.1 8.7 6.1 1.6 2.8 3 0 0 3 3 3 0 Cytoplasmic domain of voltage-gated Na+ ion channel ATG101 PF07855.12 CBZ35062.1 - 1.3 9.0 6.4 2.2 8.2 0.2 2.4 1 1 1 2 2 2 0 Autophagy-related protein 101 GHL13 PF14883.6 CBZ35065.1 - 0.012 14.7 0.7 0.016 14.3 0.7 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 NuA4 PF09340.10 CBZ35066.1 - 1.3e-08 34.6 0.0 2.4e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Histone acetyltransferase subunit NuA4 MCM2_N PF12619.8 CBZ35066.1 - 0.41 10.9 8.6 4.6 7.5 7.1 2.1 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 HEAT PF02985.22 CBZ35067.1 - 0.0024 18.0 0.7 2.6 8.6 0.0 4.6 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 CBZ35067.1 - 0.008 16.2 0.0 0.03 14.4 0.0 2.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CBZ35067.1 - 0.051 12.1 0.0 0.11 11.0 0.0 1.5 1 0 0 1 1 1 0 Adaptin N terminal region YcbB PF08664.10 CBZ35067.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 YcbB domain PNISR PF15996.5 CBZ35067.1 - 5.7 7.2 8.7 4 7.7 0.5 2.5 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR DNA_binding_1 PF01035.20 CBZ35068.1 - 5.1e-20 71.4 0.4 1.1e-19 70.3 0.0 1.8 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain zf-Di19 PF05605.12 CBZ35069.1 - 0.066 13.5 0.0 0.066 13.5 0.0 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CBZ35069.1 - 0.87 10.6 0.1 0.87 10.6 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger ELMO_CED12 PF04727.13 CBZ35073.1 - 1.5e-42 145.7 0.0 2e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family DUF35_N PF12172.8 CBZ35073.1 - 0.072 13.0 0.2 0.19 11.6 0.2 1.8 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) LRR_6 PF13516.6 CBZ35075.1 - 0.0099 15.9 11.1 0.75 10.0 0.2 5.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 CBZ35075.1 - 0.011 16.2 1.4 5.2 7.6 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ35075.1 - 0.02 14.6 0.7 28 4.6 0.1 4.1 5 0 0 5 5 5 0 Leucine rich repeat DUF4460 PF14687.6 CBZ35076.1 - 6.7e-08 32.6 0.0 1.8e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 CBZ35076.1 - 0.032 14.0 1.5 0.54 10.0 1.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4461) DUF2959 PF11172.8 CBZ35076.1 - 0.21 11.7 2.4 5.9 7.0 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Sedlin_N PF04628.13 CBZ35077.1 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region HEAT_2 PF13646.6 CBZ35079.1 - 5.5e-27 94.0 7.9 2.4e-15 56.7 0.8 3.3 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 CBZ35079.1 - 1.8e-18 65.3 9.4 0.001 19.5 0.1 6.0 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.22 CBZ35079.1 - 7.2e-08 32.1 4.5 0.0042 17.2 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 CBZ35079.1 - 5.5e-05 23.6 1.9 0.051 14.1 0.6 4.2 3 1 1 4 4 4 1 HEAT-like repeat DUF5463 PF17551.2 CBZ35079.1 - 0.15 12.0 0.2 0.31 11.0 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5463) DMRT-like PF15791.5 CBZ35079.1 - 0.16 12.4 4.4 0.9 10.0 0.7 2.9 2 1 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 DUF4457 PF14652.6 CBZ35080.1 - 1e-21 77.5 0.0 4.5e-07 29.4 0.0 5.1 5 0 0 5 5 5 4 Domain of unknown function (DUF4457) 4HBT_2 PF13279.6 CBZ35081.1 - 8.7e-11 42.4 0.0 1.3e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 CBZ35081.1 - 1e-08 35.4 0.1 4e-07 30.3 0.0 2.6 3 0 0 3 3 3 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 CBZ35081.1 - 0.054 12.8 0.0 0.14 11.4 0.0 1.7 1 1 0 1 1 1 0 Acyl-ACP thioesterase NdhS PF11623.8 CBZ35082.1 - 0.006 16.2 6.0 9.6 5.9 0.0 6.1 8 0 0 8 8 8 2 NAD(P)H dehydrogenase subunit S MT PF12777.7 CBZ35082.1 - 0.0068 15.5 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor PUB_1 PF18486.1 CBZ35082.1 - 0.014 15.2 2.3 2.7 7.9 0.1 4.9 5 0 0 5 5 5 0 PNGase/UBA- or UBX-containing domain T4_tail_cap PF11091.8 CBZ35082.1 - 0.052 12.5 0.0 10 4.9 0.0 2.4 2 0 0 2 2 2 0 Tail-tube assembly protein Brucella_OMP2 PF05244.11 CBZ35082.1 - 0.23 10.8 5.2 14 5.0 0.1 4.2 4 0 0 4 4 4 0 Brucella outer membrane protein 2 dCache_3 PF14827.6 CBZ35082.1 - 0.43 10.2 1.8 0.5 10.0 0.1 2.0 2 0 0 2 2 2 0 Double sensory domain of two-component sensor kinase DUF1459 PF07312.11 CBZ35082.1 - 0.52 10.6 2.7 4.4 7.6 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1459) COMMD1_N PF17221.3 CBZ35083.1 - 0.14 12.5 0.7 0.57 10.5 0.7 2.0 1 0 0 1 1 1 0 COMMD1 N-terminal domain SCO1-SenC PF02630.14 CBZ35084.1 - 3.4e-45 153.3 0.0 6.3e-45 152.4 0.0 1.5 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 CBZ35084.1 - 0.0049 17.2 0.0 0.0094 16.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CBZ35084.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family Methyltransf_31 PF13847.6 CBZ35087.1 - 4.3e-13 49.3 0.0 2.1e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ35087.1 - 1.4e-12 47.8 0.0 2.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ35087.1 - 6.8e-11 42.7 0.0 6e-08 33.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ35087.1 - 1.2e-09 38.8 0.0 1.5e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ35087.1 - 1.5e-09 38.4 0.0 2.7e-05 24.8 0.0 3.0 1 1 2 3 3 3 2 Methyltransferase domain DREV PF05219.12 CBZ35087.1 - 0.0004 19.6 0.0 0.001 18.2 0.0 1.7 1 1 0 1 1 1 1 DREV methyltransferase CMAS PF02353.20 CBZ35087.1 - 0.01 15.1 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PHD PF00628.29 CBZ35088.1 - 0.00098 19.0 3.9 0.002 18.0 3.9 1.5 1 0 0 1 1 1 1 PHD-finger Zn_ribbon_17 PF17120.5 CBZ35088.1 - 0.14 11.8 2.4 0.33 10.6 2.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ATG22 PF11700.8 CBZ35090.1 - 0.011 14.4 0.0 0.019 13.6 0.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like HEAT PF02985.22 CBZ35090.1 - 0.32 11.4 5.0 0.7 10.3 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat PQ-loop PF04193.14 CBZ35091.1 - 4.1e-20 71.3 0.1 3.9e-14 52.1 0.0 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 CBZ35091.1 - 0.011 16.6 0.6 0.011 16.6 0.6 2.1 2 0 0 2 2 2 0 ER lumen protein retaining receptor MtN3_slv PF03083.16 CBZ35091.1 - 0.067 13.2 2.5 9.8 6.3 0.6 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF1180 PF06679.12 CBZ35091.1 - 0.31 11.5 1.0 0.53 10.7 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Pkinase PF00069.25 CBZ35093.1 - 7e-13 48.5 0.0 1.4e-09 37.8 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35093.1 - 1.7e-08 34.1 0.4 1.5e-05 24.4 0.0 2.9 2 1 0 3 3 3 2 Protein tyrosine kinase Peptidase_C48 PF02902.19 CBZ35094.1 - 1.7e-14 54.2 0.0 3.6e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Metallophos PF00149.28 CBZ35097.1 - 5.6e-15 56.4 0.0 3.4e-13 50.6 0.0 2.8 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 CBZ35098.1 - 4.4e-33 114.8 0.0 1.1e-15 57.8 0.0 3.7 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35098.1 - 9.1e-07 28.4 0.0 4.6e-05 22.8 0.0 2.9 4 0 0 4 4 4 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBZ35098.1 - 0.00043 19.3 0.0 0.00065 18.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBZ35098.1 - 0.045 12.5 0.0 0.091 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CBZ35099.1 - 4.2e-07 29.6 0.0 8.1e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase PF00069.25 CBZ35100.1 - 4.2e-07 29.6 0.0 8.1e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Limkain-b1 PF11608.8 CBZ35101.1 - 0.051 13.7 0.1 0.15 12.2 0.1 1.8 1 1 0 1 1 1 0 Limkain b1 RRM_1 PF00076.22 CBZ35101.1 - 0.15 11.9 0.0 5.4 6.9 0.1 2.7 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pet191_N PF10203.9 CBZ35102.1 - 0.0078 16.5 3.0 0.14 12.5 0.4 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 CBZ35102.1 - 0.73 9.9 3.8 1.5 8.9 0.2 2.5 1 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, FtsJ PF01728.19 CBZ35103.1 - 2.8e-06 27.6 0.0 1e-05 25.7 0.0 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Dicty_REP PF05086.12 CBZ35105.1 - 0.43 8.5 0.4 0.6 8.0 0.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Arf PF00025.21 CBZ35107.1 - 1.7e-22 79.7 0.3 2.5e-09 36.8 0.0 4.3 4 0 0 4 4 4 3 ADP-ribosylation factor family G-alpha PF00503.20 CBZ35107.1 - 1.6e-06 27.6 0.0 0.00027 20.2 0.0 2.5 2 1 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CBZ35107.1 - 0.001 19.3 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 CBZ35107.1 - 0.0037 16.8 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CBZ35107.1 - 0.0037 16.7 0.0 4.3 6.7 0.0 2.7 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 CBZ35107.1 - 0.0041 16.8 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 CBZ35107.1 - 0.013 15.4 0.1 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 CBZ35107.1 - 0.019 15.0 0.0 0.15 12.2 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CBZ35107.1 - 0.026 15.0 0.0 0.042 14.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Ras PF00071.22 CBZ35107.1 - 0.039 13.6 0.0 52 3.4 0.0 3.6 3 1 0 3 3 3 0 Ras family AAA_28 PF13521.6 CBZ35107.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CBZ35107.1 - 0.18 11.7 0.0 17 5.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Yip1 PF04893.17 CBZ35108.1 - 0.0017 18.1 12.3 0.0027 17.4 12.3 1.3 1 0 0 1 1 1 1 Yip1 domain DUF2273 PF10031.9 CBZ35108.1 - 6.2 6.9 6.4 5.7 7.0 1.7 2.5 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) AAA_16 PF13191.6 CBZ35109.1 - 9.9e-07 29.3 5.9 9.7e-06 26.1 0.3 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CBZ35109.1 - 3.2e-06 27.5 0.0 0.066 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain Ribosomal_L38e PF01781.18 CBZ35110.1 - 2.9e-29 101.0 4.0 3.4e-29 100.7 4.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family GDP_Man_Dehyd PF16363.5 CBZ35111.1 - 1.8e-61 208.4 0.0 5.9e-56 190.3 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CBZ35111.1 - 6.5e-52 176.4 0.1 1.2e-51 175.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CBZ35111.1 - 1.5e-21 76.6 0.0 2.7e-16 59.4 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CBZ35111.1 - 1.9e-21 76.4 0.1 1.3e-17 63.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 CBZ35111.1 - 1.1e-19 70.6 0.7 2.7e-18 66.1 0.5 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CBZ35111.1 - 2.3e-18 66.4 0.0 3.9e-12 45.9 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CBZ35111.1 - 0.00038 20.4 0.1 0.02 14.8 0.0 3.0 2 1 0 3 3 3 1 NAD(P)H-binding Aminotran_5 PF00266.19 CBZ35112.1 - 8.5e-16 57.9 0.0 1.1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CBZ35112.1 - 2.6e-05 23.0 0.0 3.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CBZ35112.1 - 0.00084 18.7 0.6 0.0015 17.9 0.3 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CBZ35112.1 - 0.031 13.5 0.0 0.085 12.0 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class I and II DUF2383 PF09537.10 CBZ35113.1 - 0.12 12.8 0.2 0.68 10.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Sec1 PF00995.23 CBZ35114.1 - 1.5e-87 295.2 0.0 1.8e-87 295.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MRP-S34 PF16053.5 CBZ35115.1 - 2.7e-05 23.8 0.0 3.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 CN_hydrolase PF00795.22 CBZ35116.1 - 9.8e-51 172.6 0.0 1.1e-50 172.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Esterase PF00756.20 CBZ35117.1 - 0.045 13.4 0.0 0.09 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DUF3450 PF11932.8 CBZ35118.1 - 0.0014 18.0 8.6 0.0014 18.0 8.6 8.6 8 2 1 9 9 9 1 Protein of unknown function (DUF3450) Tnp_22_trimer PF17489.2 CBZ35118.1 - 0.056 13.4 0.4 7.2 6.7 0.0 4.2 4 0 0 4 4 4 0 L1 transposable element trimerization domain Surfac_D-trimer PF09006.11 CBZ35118.1 - 0.2 11.6 0.7 3.2 7.7 0.0 3.2 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DASH_Dam1 PF08653.10 CBZ35118.1 - 1.8 8.4 12.9 8.6 6.3 0.2 7.1 6 2 2 8 8 8 0 DASH complex subunit Dam1 Cauli_DNA-bind PF03310.13 CBZ35118.1 - 4.4 7.4 11.6 3.6 7.7 0.5 4.6 4 0 0 4 4 4 0 Caulimovirus DNA-binding protein Phage_fiber_2 PF03406.13 CBZ35118.1 - 5 6.8 9.5 1.9 8.1 0.1 3.6 4 0 0 4 4 4 0 Phage tail fibre repeat AMH_N PF04709.12 CBZ35119.1 - 0.021 13.8 0.8 0.023 13.6 0.8 1.1 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region PTPlike_phytase PF14566.6 CBZ35120.1 - 0.12 12.4 0.7 0.24 11.5 0.7 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate WD40 PF00400.32 CBZ35121.1 - 7.6e-09 36.1 8.9 0.025 15.5 0.8 5.0 5 0 0 5 5 4 3 WD domain, G-beta repeat BUD22 PF09073.10 CBZ35121.1 - 0.00085 18.8 21.9 0.00085 18.8 21.9 2.1 2 0 0 2 2 2 1 BUD22 DUF4533 PF15047.6 CBZ35121.1 - 0.0063 16.1 2.1 0.014 15.0 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) QRPTase_C PF01729.19 CBZ35121.1 - 0.0088 15.8 0.7 0.017 14.9 0.7 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PQQ_3 PF13570.6 CBZ35121.1 - 0.015 15.7 4.5 11 6.6 0.1 4.6 4 1 0 4 4 4 0 PQQ-like domain Nup160 PF11715.8 CBZ35121.1 - 0.062 11.9 0.0 0.41 9.2 0.0 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Cwf_Cwc_15 PF04889.12 CBZ35121.1 - 1.1 9.0 29.4 0.24 11.1 21.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CNDH2_C PF16858.5 CBZ35121.1 - 2.8 7.7 23.8 0.21 11.5 16.2 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Pes-10 PF07149.11 CBZ35121.1 - 3.5 6.6 30.8 0.0097 15.0 21.1 1.5 2 0 0 2 2 2 0 Pes-10 Nop14 PF04147.12 CBZ35121.1 - 6.4 4.9 29.8 0.16 10.2 21.7 1.9 2 0 0 2 2 2 0 Nop14-like family FAM60A PF15396.6 CBZ35121.1 - 7.1 6.6 12.1 4.6 7.2 8.6 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Ribosomal_L29 PF00831.23 CBZ35122.1 - 1.5e-18 66.5 2.2 1.5e-18 66.5 2.2 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 CBZ35122.1 - 0.026 14.6 0.5 0.026 14.6 0.5 2.0 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 CBZ35123.1 - 1.5e-18 66.5 2.2 1.5e-18 66.5 2.2 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 CBZ35123.1 - 0.026 14.6 0.5 0.026 14.6 0.5 2.0 2 0 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Sec1 PF00995.23 CBZ35125.1 - 1.4e-88 298.7 0.0 1.5e-88 298.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Kelch_1 PF01344.25 CBZ35125.1 - 0.042 13.5 0.0 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 Kelch motif HECT PF00632.25 CBZ35126.1 - 5.3e-34 118.1 0.0 1.2e-33 116.9 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBZ35126.1 - 1.9e-13 50.6 0.0 2.4e-09 37.3 0.0 3.4 3 0 0 3 3 3 2 SPRY domain zf-RanBP PF00641.18 CBZ35126.1 - 2.1e-07 30.1 14.1 3.1e-05 23.2 2.5 2.8 1 1 1 2 2 2 2 Zn-finger in Ran binding protein and others fn3 PF00041.21 CBZ35127.1 - 3.7e-96 315.6 55.4 7.2e-05 23.1 0.2 38.1 41 1 0 41 41 41 21 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 CBZ35127.1 - 4.9e-46 155.2 45.3 0.0041 17.7 0.9 29.5 30 1 0 30 30 30 10 Purple acid Phosphatase, N-terminal domain Interfer-bind PF09294.10 CBZ35127.1 - 9.2e-16 58.1 7.9 0.68 10.3 0.1 14.6 15 0 0 15 15 15 2 Interferon-alpha/beta receptor, fibronectin type III Glyco_hydro_36C PF16874.5 CBZ35127.1 - 1.4e-06 28.7 0.0 7.5 7.1 0.0 9.7 12 0 0 12 12 12 1 Glycosyl hydrolase family 36 C-terminal domain Y_Y_Y PF07495.13 CBZ35127.1 - 0.0029 17.5 0.0 5.2 7.1 0.0 5.1 6 0 0 6 6 6 1 Y_Y_Y domain fn3_4 PF16794.5 CBZ35127.1 - 0.0034 17.3 0.0 1.3 9.0 0.0 4.9 6 0 0 6 6 6 1 Fibronectin-III type domain Collagen_bind_2 PF12904.7 CBZ35127.1 - 0.0047 16.9 0.0 12 5.9 0.0 6.0 7 0 0 7 7 7 1 Putative collagen-binding domain of a collagenase DUF4129 PF13559.6 CBZ35127.1 - 0.089 13.1 2.8 1.3 9.3 2.8 3.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) DUF2369 PF10179.9 CBZ35127.1 - 0.13 12.7 7.5 45 4.5 0.0 7.3 8 0 0 8 8 8 0 Uncharacterised conserved protein (DUF2369) zf-primase PF09329.11 CBZ35128.1 - 6.4e-10 38.7 0.5 1.3e-09 37.7 0.5 1.5 1 0 0 1 1 1 1 Primase zinc finger Mcm10 PF09332.11 CBZ35128.1 - 2.1e-08 34.0 1.0 3.9e-08 33.1 1.0 1.5 1 0 0 1 1 1 1 Mcm10 replication factor Tim17 PF02466.19 CBZ35129.1 - 1.7e-09 38.0 1.4 5.9e-09 36.3 0.9 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5645 PF18713.1 CBZ35130.1 - 0.034 14.5 0.2 0.085 13.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) Lyase_1 PF00206.20 CBZ35130.1 - 0.071 12.5 0.0 2.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Lyase DUF3772 PF12607.8 CBZ35130.1 - 1.7 8.5 5.0 1.3 8.9 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) BTB PF00651.31 CBZ35131.1 - 1.1e-10 41.7 0.1 0.0012 19.1 0.2 3.0 2 2 0 2 2 2 2 BTB/POZ domain MATH PF00917.26 CBZ35131.1 - 0.00012 22.3 0.0 0.00022 21.4 0.0 1.3 1 0 0 1 1 1 1 MATH domain JAB PF01398.21 CBZ35132.1 - 1.8e-08 34.4 0.1 4.4e-08 33.1 0.2 1.7 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CBZ35132.1 - 8.1e-06 25.6 0.5 1.2e-05 25.1 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.25 CBZ35133.1 - 2.7e-44 151.5 0.0 3.5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35133.1 - 2.6e-32 112.2 0.0 3.8e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBZ35133.1 - 0.00043 19.7 0.4 0.00079 18.8 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBZ35133.1 - 0.0057 16.0 0.1 0.019 14.3 0.1 1.7 1 1 0 1 1 1 1 Kinase-like DUF2513 PF10711.9 CBZ35134.1 - 0.081 13.2 0.0 0.23 11.7 0.0 1.8 2 0 0 2 2 2 0 Hypothetical protein (DUF2513) RRM_1 PF00076.22 CBZ35134.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Stc1 PF12898.7 CBZ35136.1 - 0.1 13.2 10.4 0.32 11.6 2.1 2.5 1 1 1 2 2 2 0 Stc1 domain CDP-OH_P_transf PF01066.21 CBZ35137.1 - 2.5e-12 47.4 3.5 2.5e-12 47.4 3.5 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Atg14 PF10186.9 CBZ35138.1 - 0.0034 16.5 14.4 0.0034 16.5 14.4 9.7 3 2 5 9 9 9 2 Vacuolar sorting 38 and autophagy-related subunit 14 CC2-LZ PF16516.5 CBZ35138.1 - 0.0068 16.7 6.2 0.0068 16.7 6.2 14.6 10 5 5 16 16 16 3 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator APG6_N PF17675.1 CBZ35138.1 - 0.0077 16.8 0.0 0.0077 16.8 0.0 14.3 4 3 7 13 13 13 3 Apg6 coiled-coil region JIP_LZII PF16471.5 CBZ35138.1 - 0.021 15.0 0.2 0.021 15.0 0.2 16.1 17 3 1 20 20 20 0 JNK-interacting protein leucine zipper II DUF2205 PF10224.9 CBZ35138.1 - 0.023 14.7 0.7 0.023 14.7 0.7 12.8 14 2 2 16 16 16 0 Short coiled-coil protein MTCP1 PF08991.10 CBZ35140.1 - 0.00018 21.7 4.3 0.025 14.8 0.7 2.3 2 0 0 2 2 2 2 Mature-T-Cell Proliferation I type CHCH PF06747.13 CBZ35140.1 - 0.0017 18.4 9.9 0.12 12.6 4.5 2.7 2 1 0 2 2 2 2 CHCH domain CX9C PF16860.5 CBZ35140.1 - 0.0079 16.2 2.4 0.0079 16.2 2.4 2.5 3 0 0 3 3 3 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, STI1 PF17830.1 CBZ35140.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 STI1 domain NHR2 PF08788.11 CBZ35140.1 - 0.12 12.2 3.8 0.16 11.8 3.3 1.5 1 1 0 1 1 1 0 NHR2 domain like COX6B PF02297.17 CBZ35140.1 - 8.4 6.7 10.7 1.4 9.2 6.8 1.9 2 1 0 2 2 2 0 Cytochrome oxidase c subunit VIb Pkinase PF00069.25 CBZ35141.1 - 5.5e-49 166.9 0.0 6.8e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35141.1 - 1.5e-28 99.8 0.0 2.2e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FYVE PF01363.21 CBZ35141.1 - 4.9e-09 36.2 13.3 1.1e-08 35.1 13.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger Pkinase_fungal PF17667.1 CBZ35141.1 - 0.00025 20.0 0.0 0.00039 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ35141.1 - 0.0017 18.3 0.0 0.0068 16.4 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ35141.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DnaJ PF00226.31 CBZ35142.1 - 9.6e-06 25.6 0.0 2.9e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain zf-LITAF-like PF10601.9 CBZ35142.1 - 0.26 11.6 14.6 0.39 11.0 7.5 2.5 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain TFIIA PF03153.13 CBZ35142.1 - 0.9 9.5 14.4 2.6 7.9 2.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GEMIN8 PF15348.6 CBZ35142.1 - 4.5 7.5 13.4 0.64 10.3 3.8 2.4 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Metallophos PF00149.28 CBZ35143.1 - 2.6e-34 119.5 0.0 3.9e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPR PF01535.20 CBZ35144.1 - 0.0044 17.2 0.0 1.8 9.0 0.0 3.0 2 0 0 2 2 2 2 PPR repeat DUF4376 PF14301.6 CBZ35144.1 - 0.023 15.0 0.0 0.12 12.8 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) SET PF00856.28 CBZ35146.1 - 1.1e-13 51.9 0.0 1.1e-11 45.5 0.0 2.3 1 1 0 1 1 1 1 SET domain Dala_Dala_lig_C PF07478.13 CBZ35146.1 - 2.4e-12 46.8 0.0 4.3e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBZ35146.1 - 0.00024 20.7 0.0 0.0004 20.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CBZ35146.1 - 0.0042 17.2 0.0 0.0075 16.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 CBZ35146.1 - 0.011 15.4 0.0 0.048 13.3 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain Pkinase PF00069.25 CBZ35147.1 - 3.8e-45 154.3 0.0 6e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35147.1 - 9.5e-34 116.8 0.0 1.2e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ35147.1 - 0.0026 16.6 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase TrmO_C PF18389.1 CBZ35147.1 - 0.012 15.7 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 TrmO C-terminal domain APH PF01636.23 CBZ35147.1 - 0.067 13.1 0.8 0.13 12.1 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family PqiA PF04403.13 CBZ35149.1 - 3.9e-13 49.5 23.0 2.5e-11 43.6 10.0 3.7 3 1 1 4 4 4 2 Paraquat-inducible protein A Golgin_A5 PF09787.9 CBZ35150.1 - 0.013 15.0 6.0 0.11 11.9 1.2 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 FAD_binding_3 PF01494.19 CBZ35151.1 - 1.4e-12 47.5 0.0 3.8e-10 39.6 0.0 2.8 2 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 CBZ35151.1 - 1e-06 28.8 0.0 3.5e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBZ35151.1 - 0.00021 20.5 0.1 0.00054 19.2 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CBZ35151.1 - 0.00035 19.9 0.0 0.0022 17.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ35151.1 - 0.00044 20.7 0.0 0.00095 19.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBZ35151.1 - 0.0015 18.2 0.1 0.005 16.5 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CBZ35151.1 - 0.017 14.2 0.6 0.049 12.7 0.0 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 CBZ35151.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 CBZ35151.1 - 0.21 10.8 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2798 PF11391.8 CBZ35152.1 - 0.084 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) zf-CSL PF05207.13 CBZ35153.1 - 2.4e-15 56.0 0.3 3.3e-15 55.5 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger Bacillus_HBL PF05791.11 CBZ35154.1 - 0.0039 17.0 0.8 0.0066 16.3 0.8 1.3 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) CLZ PF16526.5 CBZ35154.1 - 0.014 15.7 0.5 0.033 14.5 0.5 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fzo_mitofusin PF04799.13 CBZ35154.1 - 0.056 13.0 0.1 2.5 7.7 0.1 2.4 2 1 0 2 2 2 0 fzo-like conserved region Uso1_p115_C PF04871.13 CBZ35154.1 - 0.13 12.7 1.7 0.28 11.5 1.7 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region HECT PF00632.25 CBZ35155.1 - 3.2e-07 30.1 0.0 0.00012 21.6 0.0 2.8 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) RTT107_BRCT_5 PF16770.5 CBZ35156.1 - 0.024 14.5 0.0 0.1 12.5 0.0 2.1 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain ABC_membrane PF00664.23 CBZ35157.1 - 3.4e-97 325.4 26.5 1e-53 182.8 9.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ35157.1 - 2.5e-68 228.9 0.1 3.3e-34 118.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBZ35157.1 - 1.2e-11 44.5 0.6 7.3e-06 25.6 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CBZ35157.1 - 6.8e-06 25.5 0.0 0.004 16.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 CBZ35157.1 - 1.7e-05 24.5 0.6 0.13 12.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBZ35157.1 - 1.9e-05 24.7 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 CBZ35157.1 - 7.3e-05 23.2 1.0 0.5 10.8 0.1 3.9 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ35157.1 - 0.00021 21.7 0.2 0.6 10.5 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CBZ35157.1 - 0.00028 19.8 0.1 0.0071 15.2 0.1 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 CBZ35157.1 - 0.00041 20.9 1.0 0.61 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CBZ35157.1 - 0.00041 20.2 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 CBZ35157.1 - 0.0013 18.7 0.1 0.2 11.5 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 CBZ35157.1 - 0.0013 19.0 1.9 0.45 10.8 0.1 3.6 2 2 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 CBZ35157.1 - 0.0015 18.2 0.2 1.7 8.3 0.0 2.7 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain 7TM_GPCR_Srh PF10318.9 CBZ35157.1 - 0.0026 16.8 1.3 0.0026 16.8 1.3 2.3 3 0 0 3 3 2 1 Serpentine type 7TM GPCR chemoreceptor Srh AAA_7 PF12775.7 CBZ35157.1 - 0.003 17.1 0.1 0.67 9.4 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 CBZ35157.1 - 0.0035 16.9 2.4 6.7 6.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.14 CBZ35157.1 - 0.0056 16.7 0.2 0.66 10.0 0.0 3.4 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 CBZ35157.1 - 0.0061 15.8 0.1 0.78 8.8 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit RNA_helicase PF00910.22 CBZ35157.1 - 0.0076 16.6 0.2 7.4 7.0 0.1 2.9 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 CBZ35157.1 - 0.0085 16.2 0.4 2.3 8.3 0.1 2.7 2 0 0 2 2 2 1 Helicase HerA, central domain Viral_helicase1 PF01443.18 CBZ35157.1 - 0.02 14.7 0.1 12 5.5 0.0 3.1 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.6 CBZ35157.1 - 0.067 13.4 7.1 16 5.8 0.7 4.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 CBZ35157.1 - 0.079 12.3 0.0 33 3.8 0.0 3.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CBZ35157.1 - 0.088 13.0 0.4 6.2 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBZ35157.1 - 0.095 13.3 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain MoaE PF02391.17 CBZ35157.1 - 0.097 13.0 1.3 1.6 9.0 0.0 3.2 4 0 0 4 4 2 0 MoaE protein DUF815 PF05673.13 CBZ35157.1 - 0.12 11.6 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 CBZ35157.1 - 0.17 11.7 0.1 6 6.6 0.0 2.7 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NTPase_1 PF03266.15 CBZ35157.1 - 0.17 11.7 2.1 48 3.8 0.1 3.5 2 1 0 3 3 3 0 NTPase MMR_HSR1 PF01926.23 CBZ35157.1 - 0.21 11.7 0.6 30 4.7 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase DEAD PF00270.29 CBZ35157.1 - 0.3 10.9 2.5 1.3 8.8 0.2 2.9 2 2 0 2 2 2 0 DEAD/DEAH box helicase NB-ARC PF00931.22 CBZ35157.1 - 0.38 9.9 1.9 10 5.2 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain CPBP PF02517.16 CBZ35159.1 - 4.5e-20 71.8 0.9 4.5e-20 71.8 0.9 1.9 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Glucosamine_iso PF01182.20 CBZ35160.1 - 1.1e-52 179.2 0.0 1.2e-52 179.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase AA_kinase PF00696.28 CBZ35161.1 - 1.6e-40 139.2 0.3 2e-40 138.9 0.3 1.0 1 0 0 1 1 1 1 Amino acid kinase family TPR_2 PF07719.17 CBZ35162.1 - 0.00042 20.2 2.3 1 9.6 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ35162.1 - 0.00084 19.8 3.0 2.2 8.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 CBZ35162.1 - 0.0017 18.6 0.9 0.076 13.3 0.0 3.5 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ35162.1 - 0.0051 17.5 6.1 1.1 10.3 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ35162.1 - 0.014 16.0 3.9 1.3 9.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ35162.1 - 0.021 15.4 2.2 30 5.4 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ35162.1 - 0.072 13.4 0.5 19 5.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Meckelin PF09773.9 CBZ35163.1 - 9.4e-240 798.1 5.9 9.4e-240 798.1 5.9 1.4 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) hEGF PF12661.7 CBZ35163.1 - 1.5 9.5 8.0 18 6.2 0.7 3.8 3 0 0 3 3 3 0 Human growth factor-like EGF TGT PF01702.18 CBZ35164.1 - 6.5e-29 101.2 0.0 7.9e-28 97.6 0.0 1.9 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Peptidase_M48_N PF16491.5 CBZ35165.1 - 5e-42 143.8 2.6 8.7e-42 143.1 2.6 1.3 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CBZ35165.1 - 3.1e-41 141.3 0.0 6.2e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 CBZ35165.1 - 0.013 14.7 0.5 0.028 13.6 0.2 1.8 2 0 0 2 2 2 0 BlaR1 peptidase M56 DEAD PF00270.29 CBZ35166.1 - 3.9e-39 134.2 0.7 5.9e-39 133.6 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ35166.1 - 6.4e-23 81.2 0.0 6.5e-20 71.5 0.0 3.7 2 1 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBZ35166.1 - 1.2e-08 35.1 0.7 8.3e-08 32.3 0.2 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBZ35166.1 - 6.4e-08 32.8 0.0 2.7e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ35166.1 - 0.17 12.1 2.4 2.2 8.6 1.2 3.0 2 1 0 2 2 2 0 AAA domain p450 PF00067.22 CBZ35170.1 - 1.8e-53 181.9 0.0 2.5e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_L PF01193.24 CBZ35170.1 - 0.34 10.4 1.4 0.59 9.6 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 CBZ35171.1 - 3.4e-67 226.6 0.0 4.8e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35171.1 - 2.2e-27 96.0 0.0 3.7e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PUL PF08324.11 CBZ35171.1 - 0.0076 15.5 0.0 0.58 9.3 0.0 2.2 2 0 0 2 2 2 2 PUL domain Beta-lactamase2 PF13354.6 CBZ35171.1 - 0.089 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase enzyme family DUF4692 PF15763.5 CBZ35171.1 - 8.4 6.8 7.2 4.3 7.8 1.1 2.8 2 1 1 3 3 3 0 Regulator of human erythroid cell expansion (RHEX) RINGv PF12906.7 CBZ35173.1 - 4e-10 39.7 11.7 8.2e-10 38.6 11.7 1.5 1 0 0 1 1 1 1 RING-variant domain WW PF00397.26 CBZ35174.1 - 1.7e-11 44.0 1.7 4e-11 42.8 1.7 1.7 1 0 0 1 1 1 1 WW domain zf_CCCH_4 PF18345.1 CBZ35174.1 - 2.6e-06 27.3 3.6 4.7e-06 26.5 3.6 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CBZ35174.1 - 3.3e-06 26.9 0.7 5.4e-06 26.2 0.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ35174.1 - 2.9e-05 23.8 1.6 5.1e-05 23.0 1.6 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CBZ35174.1 - 0.014 16.1 0.1 0.017 15.8 0.1 1.3 1 0 0 1 1 1 0 Torus domain Torus PF16131.5 CBZ35176.1 - 5.4e-07 30.3 0.1 1.3e-06 29.0 0.1 1.6 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 CBZ35176.1 - 7e-07 29.1 2.5 9.9e-07 28.6 2.5 1.2 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBZ35176.1 - 5.1e-06 26.1 1.3 7.2e-06 25.7 1.3 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CBZ35176.1 - 0.0068 16.3 0.3 0.0099 15.8 0.3 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CBZ35176.1 - 0.0072 16.8 2.5 0.011 16.2 2.5 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger SET PF00856.28 CBZ35177.1 - 1.9e-12 47.9 0.0 1.1e-11 45.4 0.0 1.9 1 1 0 1 1 1 1 SET domain OSTMP1 PF09777.9 CBZ35177.1 - 0.0039 16.6 0.2 0.0059 16.0 0.2 1.2 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor Proteasome PF00227.26 CBZ35180.1 - 1e-43 149.0 0.1 1.4e-43 148.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ35180.1 - 1.2e-08 34.5 0.1 1.2e-08 34.5 0.1 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Torus PF16131.5 CBZ35181.1 - 0.0017 19.0 0.1 0.0035 18.0 0.1 1.5 1 0 0 1 1 1 1 Torus domain Inhibitor_I36 PF03995.13 CBZ35181.1 - 0.0044 16.9 1.0 0.31 11.0 0.1 2.8 3 0 0 3 3 3 2 Peptidase inhibitor family I36 VIT1 PF01988.19 CBZ35182.1 - 2e-50 171.7 4.2 2.7e-50 171.2 4.2 1.2 1 0 0 1 1 1 1 VIT family DUF3295 PF11702.8 CBZ35184.1 - 0.0052 16.2 0.5 0.096 12.0 0.4 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3295) XPG_I PF00867.18 CBZ35186.1 - 3.6e-30 104.2 0.0 6.4e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CBZ35186.1 - 1.1e-26 93.3 0.0 2.2e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 CBZ35186.1 - 4.8e-06 27.1 0.0 3.4e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold DUF3043 PF11241.8 CBZ35186.1 - 0.043 13.9 1.6 0.08 13.0 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) XRN_N PF03159.18 CBZ35186.1 - 0.06 12.8 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus PP-binding PF00550.25 CBZ35190.1 - 1.1e-10 41.7 0.1 1.5e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site MM_CoA_mutase PF01642.22 CBZ35191.1 - 6.8e-230 764.0 0.2 8.2e-230 763.7 0.2 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 CBZ35191.1 - 2.5e-12 46.9 0.1 6.4e-12 45.6 0.1 1.7 1 0 0 1 1 1 1 B12 binding domain HisG_C PF08029.11 CBZ35191.1 - 0.053 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 HisG, C-terminal domain TIP120 PF08623.10 CBZ35192.1 - 6.4e-08 32.5 0.9 3.3e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 CBZ35192.1 - 7.2 7.2 9.9 34 5.0 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat TSNAXIP1_N PF15739.5 CBZ35194.1 - 2.1e-19 69.9 4.5 2.1e-19 69.9 4.5 2.6 2 0 0 2 2 2 1 Translin-associated factor X-interacting N-terminus Arg_decarbox_C PF17944.1 CBZ35194.1 - 0.039 14.5 2.4 40 4.9 0.2 4.2 3 0 0 3 3 3 0 Arginine decarboxylase C-terminal helical extension RRM_1 PF00076.22 CBZ35196.1 - 4.7e-14 52.0 0.0 1.1e-07 31.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.29 CBZ35197.1 - 4.2e-36 124.3 0.0 1.9e-35 122.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ35197.1 - 5.4e-08 33.4 0.3 0.049 14.0 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 CBZ35197.1 - 1.2e-06 28.3 0.1 3.4e-06 26.7 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Rad17 PF03215.15 CBZ35197.1 - 0.00062 19.7 0.0 0.006 16.5 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 CBZ35197.1 - 0.002 18.5 0.0 0.29 11.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 CBZ35197.1 - 0.0039 17.2 0.0 0.018 15.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CBZ35197.1 - 0.01 15.1 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_33 PF13671.6 CBZ35197.1 - 0.041 14.0 0.0 0.094 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ35197.1 - 0.065 12.7 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 CBZ35197.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CBZ35197.1 - 0.12 12.6 0.3 1.5 9.0 0.1 2.6 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.6 CBZ35197.1 - 0.14 12.2 0.0 0.42 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBZ35197.1 - 0.21 11.5 0.0 1.6 8.6 0.0 2.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Herpes_UL49_5 PF05702.11 CBZ35198.1 - 0.031 14.4 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Nup96 PF12110.8 CBZ35199.1 - 1.8e-34 119.2 0.0 2.9e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 CBZ35199.1 - 7.6e-14 52.1 0.0 1.4e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase APG9 PF04109.16 CBZ35200.1 - 3.1e-61 207.9 2.8 6.6e-61 206.8 2.8 1.4 1 1 0 1 1 1 1 Autophagy protein Apg9 DUF3525 PF12039.8 CBZ35200.1 - 0.041 12.6 0.3 0.065 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) KIP1 PF07765.12 CBZ35201.1 - 0.055 13.6 2.3 1.4 9.0 0.8 2.3 1 1 1 2 2 2 0 KIP1-like protein DnaJ PF00226.31 CBZ35202.1 - 1.3e-24 86.1 0.4 2.3e-24 85.3 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain DUF1353 PF07087.11 CBZ35202.1 - 0.11 12.3 0.0 6.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) MrpF_PhaF PF04066.13 CBZ35202.1 - 1.3 9.5 4.1 2.3 8.7 4.1 1.4 1 0 0 1 1 1 0 Multiple resistance and pH regulation protein F (MrpF / PhaF) PfkB PF00294.24 CBZ35203.1 - 3.4e-68 230.2 0.1 3.8e-68 230.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CBZ35203.1 - 6.2e-09 35.6 0.0 8.8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Mur_ligase PF01225.25 CBZ35203.1 - 0.022 15.1 0.0 0.17 12.2 0.0 2.5 2 1 0 2 2 2 0 Mur ligase family, catalytic domain DAO PF01266.24 CBZ35203.1 - 0.045 13.3 0.4 0.35 10.4 0.1 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Vps53_N PF04100.12 CBZ35204.1 - 0.038 12.9 1.0 0.058 12.4 1.0 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal Brix PF04427.18 CBZ35206.1 - 5.9e-27 95.0 1.0 6.3e-27 94.9 0.1 1.5 2 0 0 2 2 2 1 Brix domain Vasohibin PF14822.6 CBZ35207.1 - 1.7e-48 165.0 0.0 2.5e-48 164.4 0.0 1.2 1 0 0 1 1 1 1 Vasohibin ABC_membrane_2 PF06472.15 CBZ35208.1 - 1.8e-24 86.6 0.2 2.7e-24 86.0 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CBZ35208.1 - 4.2e-15 56.5 0.0 9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CBZ35208.1 - 5.7e-08 32.5 0.0 2.8e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 CBZ35208.1 - 1.1e-05 25.4 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_21 PF13304.6 CBZ35208.1 - 0.00063 19.6 0.0 0.034 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CBZ35208.1 - 0.0015 18.3 0.0 0.0048 16.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ35208.1 - 0.0016 18.7 0.3 1.4 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CBZ35208.1 - 0.0061 17.1 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ35208.1 - 0.018 15.4 0.0 0.048 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain HTH_43 PF09904.9 CBZ35208.1 - 0.075 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn helix AAA_29 PF13555.6 CBZ35208.1 - 0.1 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_membrane PF00664.23 CBZ35208.1 - 0.13 11.9 0.9 0.22 11.2 0.9 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region BcrAD_BadFG PF01869.20 CBZ35208.1 - 0.16 11.4 0.0 0.44 10.0 0.0 1.7 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DASH_Dam1 PF08653.10 CBZ35208.1 - 0.21 11.4 2.4 13 5.6 0.2 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 Peptidase_C2 PF00648.21 CBZ35211.1 - 8.9e-59 198.9 0.0 1.9e-34 119.1 0.0 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 CBZ35211.1 - 5.1e-12 46.3 0.0 4e-07 30.4 0.0 3.1 3 0 0 3 3 3 2 Calpain large subunit, domain III DUF1382 PF07131.11 CBZ35211.1 - 0.0013 18.7 3.0 54 3.9 0.0 8.6 8 0 0 8 8 8 1 Protein of unknown function (DUF1382) Peptidase_C2 PF00648.21 CBZ35212.1 - 1.2e-72 244.4 0.0 2e-37 128.8 0.0 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease Calpain_III PF01067.22 CBZ35212.1 - 9.4e-09 35.7 0.0 1.3e-06 28.7 0.0 3.1 3 0 0 3 3 3 1 Calpain large subunit, domain III CHASE3 PF05227.13 CBZ35212.1 - 9.2 6.2 9.2 5.9 6.8 0.3 3.2 3 0 0 3 3 3 0 CHASE3 domain LRR_8 PF13855.6 CBZ35213.1 - 0.23 11.2 2.7 0.57 10.0 0.0 2.6 3 0 0 3 3 3 0 Leucine rich repeat RhlB PF12300.8 CBZ35214.1 - 0.42 10.7 8.8 0.1 12.7 4.2 2.1 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB UBA PF00627.31 CBZ35216.1 - 4e-09 36.2 0.2 1.1e-08 34.8 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 CBZ35216.1 - 0.041 13.7 0.1 0.092 12.6 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain NAD_binding_1 PF00175.21 CBZ35217.1 - 1.1e-18 67.8 0.0 2.1e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBZ35217.1 - 9.2e-16 58.0 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBZ35217.1 - 0.00025 21.2 0.0 0.00095 19.3 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Oxidored_q6 PF01058.22 CBZ35218.1 - 2.8e-19 69.3 0.1 3.7e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Dabb PF07876.12 CBZ35219.1 - 9.7e-08 32.5 0.0 1.5e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Dabb PF07876.12 CBZ35220.1 - 1.4e-06 28.8 0.0 1.9e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ras PF00071.22 CBZ35221.1 - 5e-64 214.8 0.6 5.7e-64 214.6 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ35221.1 - 3.6e-37 127.2 0.1 6e-37 126.5 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ35221.1 - 3.4e-16 59.2 0.1 4.2e-16 58.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBZ35221.1 - 4.9e-07 29.8 0.7 0.0057 16.6 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CBZ35221.1 - 9.3e-07 28.4 0.1 1.1e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBZ35221.1 - 2.9e-05 23.6 0.1 3.7e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBZ35221.1 - 4.9e-05 23.0 0.3 0.00012 21.7 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ35221.1 - 8.6e-05 22.6 0.1 0.00026 21.0 0.0 1.7 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ35221.1 - 0.00052 19.6 0.1 0.0027 17.3 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 CBZ35221.1 - 0.01 16.2 0.0 0.85 10.0 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ35221.1 - 0.014 15.8 0.0 0.024 15.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CBZ35221.1 - 0.016 15.7 0.2 0.099 13.2 0.2 1.9 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 CBZ35221.1 - 0.028 13.6 4.1 0.09 11.9 0.8 2.5 1 1 1 2 2 2 0 G-protein alpha subunit AAA_22 PF13401.6 CBZ35221.1 - 0.055 13.7 0.0 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CBZ35221.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 CBZ35221.1 - 0.093 12.1 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 CBZ35221.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 CBZ35221.1 - 0.14 12.1 0.1 0.28 11.2 0.0 1.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Pkinase PF00069.25 CBZ35222.1 - 0.038 13.4 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain MCU PF04678.13 CBZ35223.1 - 5.8e-46 156.8 0.1 8.7e-46 156.2 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter LCE PF14672.6 CBZ35223.1 - 0.0023 18.5 0.8 0.0049 17.4 0.8 1.6 1 0 0 1 1 1 1 Late cornified envelope Glyoxalase_4 PF13669.6 CBZ35223.1 - 0.0098 16.2 0.1 0.023 15.0 0.1 1.6 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GerA PF03323.13 CBZ35223.1 - 0.076 11.5 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein FLILHELTA PF10306.9 CBZ35223.1 - 0.23 11.9 0.8 1.1 9.6 0.1 2.4 3 0 0 3 3 3 0 Hypothetical protein FLILHELTA MatE PF01554.18 CBZ35224.1 - 1.9e-37 128.4 22.3 9.4e-20 70.9 8.0 2.4 2 0 0 2 2 2 2 MatE FAM176 PF14851.6 CBZ35224.1 - 0.061 13.0 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 FAM176 family Gmad1 PF10647.9 CBZ35224.1 - 0.062 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain COP-gamma_platf PF08752.10 CBZ35224.1 - 0.41 10.8 1.7 0.74 9.9 1.7 1.4 1 0 0 1 1 1 0 Coatomer gamma subunit appendage platform subdomain LRR_6 PF13516.6 CBZ35225.1 - 0.00056 19.7 10.6 0.0096 15.9 0.2 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.6 CBZ35225.1 - 0.08 12.7 2.6 2.1 8.2 1.2 3.2 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.7 CBZ35225.1 - 0.27 11.7 2.7 7.4 7.1 1.7 3.4 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Glutaredoxin PF00462.24 CBZ35226.1 - 9e-17 61.1 0.1 1.2e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 CBZ35226.1 - 1.8e-05 25.0 0.0 2.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.6 CBZ35226.1 - 3.9e-05 23.6 0.0 5.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 CBZ35226.1 - 9.9e-05 22.8 0.2 0.00016 22.1 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 CBZ35226.1 - 0.00097 19.5 0.1 0.0011 19.3 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 CBZ35226.1 - 0.0013 18.9 0.3 1.8 8.7 0.0 2.1 1 1 0 2 2 2 2 Thioredoxin DSBA PF01323.20 CBZ35226.1 - 0.0027 17.5 0.4 0.17 11.7 0.3 2.1 1 1 1 2 2 2 1 DSBA-like thioredoxin domain Redoxin PF08534.10 CBZ35226.1 - 0.058 13.1 0.1 0.094 12.4 0.1 1.3 1 0 0 1 1 1 0 Redoxin TraF PF13728.6 CBZ35226.1 - 0.066 13.0 0.0 0.093 12.5 0.0 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein zf-RING_7 PF02591.15 CBZ35226.1 - 0.083 13.1 0.1 0.97 9.7 0.0 2.7 3 0 0 3 3 3 0 C4-type zinc ribbon domain GST_N_2 PF13409.6 CBZ35226.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Beta_helix PF13229.6 CBZ35227.1 - 1.1e-95 317.7 87.7 1.6e-15 57.3 1.2 17.1 10 4 5 15 15 15 13 Right handed beta helix region NosD PF05048.13 CBZ35227.1 - 6.8e-70 235.1 39.1 4.3e-11 42.5 6.3 15.2 9 6 6 15 15 15 13 Periplasmic copper-binding protein (NosD) zf-RING_6 PF14835.6 CBZ35227.1 - 0.025 14.4 4.3 2.1 8.3 0.0 4.6 4 0 0 4 4 4 0 zf-RING of BARD1-type protein DUF1565 PF07602.11 CBZ35227.1 - 0.28 10.5 40.6 1.1 8.6 0.0 10.6 10 3 3 14 14 14 0 Protein of unknown function (DUF1565) ADP_ribosyl_GH PF03747.14 CBZ35229.1 - 1.4 8.6 8.3 0.057 13.1 0.7 2.1 2 1 0 2 2 2 0 ADP-ribosylglycohydrolase WD40 PF00400.32 CBZ35231.1 - 5.4e-06 27.0 10.8 0.012 16.5 0.1 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat SnoaL_3 PF13474.6 CBZ35231.1 - 0.11 12.8 0.3 0.5 10.6 0.3 2.2 2 0 0 2 2 2 0 SnoaL-like domain DUF1126 PF06565.12 CBZ35232.1 - 7.7e-80 263.5 1.1 7.8e-26 89.9 0.2 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 CBZ35232.1 - 1.1e-08 35.3 3.3 8.6e-08 32.5 0.1 3.3 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 CBZ35232.1 - 7.3e-07 28.9 2.6 0.0019 18.0 0.1 3.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ35232.1 - 8.9e-06 24.9 0.8 0.25 11.0 0.0 4.7 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 CBZ35232.1 - 1.6e-05 24.5 0.2 0.1 12.6 0.1 4.3 4 0 0 4 4 4 1 EF-hand domain EF-hand_5 PF13202.6 CBZ35232.1 - 0.14 11.8 0.4 2.5 7.7 0.0 3.0 3 0 0 3 3 3 0 EF hand E1_dh PF00676.20 CBZ35234.1 - 9.1e-58 195.6 0.0 1.6e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 CBZ35234.1 - 3.2e-48 163.8 0.0 5.4e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 CBZ35234.1 - 4.4e-38 130.4 0.1 7.8e-38 129.6 0.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CBZ35234.1 - 8.5e-05 22.1 0.1 0.00018 21.0 0.1 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus PIP5K PF01504.18 CBZ35235.1 - 3.4e-34 118.3 0.0 3.7e-16 59.2 0.0 3.2 2 1 1 3 3 3 3 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 CBZ35235.1 - 1.1e-16 60.7 4.0 2.1e-16 59.8 4.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger Cpn60_TCP1 PF00118.24 CBZ35235.1 - 0.00056 18.7 0.0 0.00091 18.0 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family IBR PF01485.21 CBZ35235.1 - 0.2 11.9 3.4 0.55 10.5 3.4 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Zn-ribbon_8 PF09723.10 CBZ35235.1 - 0.33 11.1 5.4 1.4 9.1 5.4 2.1 1 0 0 1 1 1 0 Zinc ribbon domain Ribosomal_S27e PF01667.17 CBZ35235.1 - 1.7 8.4 4.3 5.2 6.9 4.3 1.8 1 0 0 1 1 1 0 Ribosomal protein S27 HypA PF01155.19 CBZ35235.1 - 2.4 8.2 5.7 3.7 7.6 1.9 2.7 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_C2HC_14 PF18574.1 CBZ35235.1 - 6.3 6.7 8.8 3.7 7.4 4.1 2.4 2 0 0 2 2 2 0 C2HC Zing finger domain DUF778 PF05608.12 CBZ35236.1 - 7.4e-34 117.8 2.9 3.2e-19 70.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF778) Pep3_Vps18 PF05131.14 CBZ35237.1 - 1.3e-08 34.8 0.0 4.5e-07 29.8 0.0 2.8 2 1 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CBZ35237.1 - 9e-08 32.1 0.0 5.1e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CBZ35237.1 - 4.1e-06 27.2 0.1 9.2e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 CBZ35237.1 - 0.0039 16.8 0.4 0.0039 16.8 0.4 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Clathrin_H_link PF13838.6 CBZ35237.1 - 0.0088 15.9 0.0 0.052 13.5 0.0 2.2 2 0 0 2 2 2 1 Clathrin-H-link zf-RING_UBOX PF13445.6 CBZ35237.1 - 0.021 14.8 0.9 0.049 13.7 0.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger vATP-synt_E PF01991.18 CBZ35237.1 - 0.072 12.5 0.0 0.35 10.2 0.0 2.0 1 1 0 2 2 2 0 ATP synthase (E/31 kDa) subunit zf-C3HC4_2 PF13923.6 CBZ35237.1 - 0.22 11.4 1.7 0.99 9.3 1.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ35237.1 - 0.91 9.5 9.0 0.033 14.2 2.5 2.1 2 1 0 2 2 2 0 zinc-RING finger domain Prok-RING_1 PF14446.6 CBZ35237.1 - 7.5 6.6 7.0 0.89 9.5 0.5 2.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DUF1295 PF06966.12 CBZ35238.1 - 3.6e-27 95.4 15.5 6.8e-27 94.5 15.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Acyl-CoA_dh_1 PF00441.24 CBZ35239.1 - 2.7e-40 138.0 1.3 3.7e-40 137.6 0.5 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBZ35239.1 - 1.8e-28 99.5 0.0 4.8e-28 98.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CBZ35239.1 - 1.6e-22 79.5 0.1 3.1e-22 78.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CBZ35239.1 - 7.3e-20 71.6 0.1 1.6e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 CBZ35239.1 - 0.14 12.7 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal XRN_N PF03159.18 CBZ35240.1 - 5.3e-25 88.3 0.0 7.8e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XPG_N PF00752.17 CBZ35240.1 - 0.048 14.1 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 XPG N-terminal domain ABC2_membrane_3 PF12698.7 CBZ35243.1 - 0.1 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.7 CBZ35244.1 - 6.5e-71 239.2 41.7 1.1e-45 156.3 14.8 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ35244.1 - 5.9e-53 179.1 0.0 5.7e-28 98.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ35244.1 - 3.1e-15 56.8 0.1 6.2e-06 26.2 0.0 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 CBZ35244.1 - 0.00011 22.8 0.0 0.034 14.9 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) SMC_N PF02463.19 CBZ35244.1 - 0.00018 21.0 0.0 2.4 7.5 0.0 3.6 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 CBZ35244.1 - 0.00043 20.1 0.0 0.047 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBZ35244.1 - 0.00062 19.5 0.2 0.12 12.1 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CBZ35244.1 - 0.00067 20.2 5.2 0.39 11.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CBZ35244.1 - 0.00072 19.5 0.0 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 CBZ35244.1 - 0.00091 18.6 0.3 2.3 7.5 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin SRP54 PF00448.22 CBZ35244.1 - 0.0047 16.6 0.8 1 8.9 0.0 2.8 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_15 PF13175.6 CBZ35244.1 - 0.0098 15.6 0.7 3.5 7.2 0.0 3.5 4 0 0 4 4 3 1 AAA ATPase domain SbcCD_C PF13558.6 CBZ35244.1 - 0.015 15.6 2.2 3.5 7.9 0.0 4.1 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 CBZ35244.1 - 0.044 14.2 0.0 0.62 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 CBZ35244.1 - 0.12 12.4 0.2 7 6.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.20 CBZ35244.1 - 0.16 11.9 0.2 0.6 10.0 0.1 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase MukB PF04310.12 CBZ35244.1 - 0.21 11.4 0.6 5.4 6.8 0.1 2.3 2 0 0 2 2 2 0 MukB N-terminal ABC2_membrane PF01061.24 CBZ35244.1 - 0.37 10.2 49.4 0.02 14.3 16.7 4.0 4 1 0 4 4 4 0 ABC-2 type transporter AAA_28 PF13521.6 CBZ35244.1 - 2 8.6 4.3 4.5 7.5 0.1 3.1 3 0 0 3 3 2 0 AAA domain TatD_DNase PF01026.21 CBZ35246.1 - 8.7e-39 133.4 0.1 1.1e-38 133.1 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 CBZ35246.1 - 0.0017 18.2 0.0 0.099 12.4 0.0 2.5 1 1 0 1 1 1 1 Amidohydrolase PriCT_1 PF08708.11 CBZ35246.1 - 0.023 14.4 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) Sec6 PF06046.13 CBZ35247.1 - 2.1e-13 49.5 2.1 2.8e-12 45.8 2.1 2.3 1 1 0 1 1 1 1 Exocyst complex component Sec6 DUF4559 PF15112.6 CBZ35247.1 - 0.46 10.1 5.1 1.7 8.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) DUF5308 PF17233.2 CBZ35248.1 - 0.029 14.6 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) LpqV PF17301.2 CBZ35248.1 - 0.029 14.6 0.1 0.26 11.5 0.0 2.4 3 0 0 3 3 3 0 Putative lipoprotein LpqV DUF896 PF05979.12 CBZ35248.1 - 0.03 14.2 0.5 0.17 11.8 0.2 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Pyridox_ox_2 PF12900.7 CBZ35248.1 - 0.1 12.6 0.4 3.1 7.8 0.1 2.2 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase DUF3446 PF11928.8 CBZ35249.1 - 8.9 6.7 10.9 1.1e+02 3.2 7.1 3.4 3 0 0 3 3 3 0 Early growth response N-terminal domain AAA PF00004.29 CBZ35252.1 - 1.2e-86 287.8 0.0 3.1e-47 160.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ35252.1 - 4.2e-23 80.9 0.6 6.5e-11 41.9 0.0 3.1 3 0 0 3 3 2 2 AAA+ lid domain RuvB_N PF05496.12 CBZ35252.1 - 3.3e-16 59.4 0.0 3e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ35252.1 - 6.9e-13 49.3 0.9 0.00059 20.3 0.1 4.3 2 2 2 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 CBZ35252.1 - 2.4e-11 43.8 0.3 0.0002 21.4 0.0 3.9 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBZ35252.1 - 5.4e-11 42.9 0.0 2.4e-05 24.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CBZ35252.1 - 6.1e-09 36.3 1.0 0.013 15.8 0.0 4.5 3 2 0 3 3 2 2 AAA domain AAA_33 PF13671.6 CBZ35252.1 - 1.6e-08 34.8 0.0 0.0058 16.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CBZ35252.1 - 1.7e-07 31.3 0.0 0.015 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CBZ35252.1 - 9.8e-07 29.1 0.0 0.034 14.5 0.0 3.1 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.6 CBZ35252.1 - 1.3e-06 29.0 0.0 0.065 13.8 0.0 3.1 3 1 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 CBZ35252.1 - 5.8e-06 26.2 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 CBZ35252.1 - 1.6e-05 24.9 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CBZ35252.1 - 2.1e-05 23.9 0.0 0.19 10.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain Zeta_toxin PF06414.12 CBZ35252.1 - 2.2e-05 23.8 0.0 0.021 14.1 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin AAA_3 PF07726.11 CBZ35252.1 - 3.7e-05 23.6 0.0 0.38 10.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CBZ35252.1 - 4.3e-05 23.0 0.2 0.049 13.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CBZ35252.1 - 6.2e-05 23.3 0.0 0.37 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CBZ35252.1 - 7.9e-05 22.6 0.2 0.34 10.8 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_24 PF13479.6 CBZ35252.1 - 9.7e-05 22.2 0.0 0.49 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CBZ35252.1 - 0.0002 21.2 0.0 0.35 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CBZ35252.1 - 0.00021 21.8 0.6 0.39 11.2 0.0 2.9 3 1 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.26 CBZ35252.1 - 0.00042 20.1 0.0 0.09 12.5 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain Vps4_C PF09336.10 CBZ35252.1 - 0.00077 19.4 0.1 0.0091 16.0 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.6 CBZ35252.1 - 0.00087 19.7 0.2 0.33 11.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CBZ35252.1 - 0.001 18.6 0.1 0.63 9.5 0.0 2.6 2 1 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 CBZ35252.1 - 0.001 19.2 0.0 0.047 13.8 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain NB-ARC PF00931.22 CBZ35252.1 - 0.0013 18.0 0.0 0.79 8.8 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.15 CBZ35252.1 - 0.0014 18.6 0.5 0.19 11.7 0.0 2.9 3 0 0 3 3 2 1 NTPase Rad17 PF03215.15 CBZ35252.1 - 0.0016 18.4 0.0 0.075 12.9 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain ATPase_2 PF01637.18 CBZ35252.1 - 0.0018 18.2 0.0 0.33 10.8 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 CBZ35252.1 - 0.002 17.9 0.0 0.51 10.0 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 CBZ35252.1 - 0.0031 17.4 0.0 1.8 8.4 0.0 2.8 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_19 PF13245.6 CBZ35252.1 - 0.0037 17.6 0.0 3.6 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 CBZ35252.1 - 0.0058 15.8 0.1 0.44 9.6 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 CBZ35252.1 - 0.0067 16.0 4.0 2.9 7.4 0.1 3.8 2 2 1 4 4 4 1 AAA domain DUF815 PF05673.13 CBZ35252.1 - 0.018 14.2 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 CBZ35252.1 - 0.022 14.5 0.1 8.2 6.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain MCM PF00493.23 CBZ35252.1 - 0.029 13.5 0.0 3 6.9 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain TniB PF05621.11 CBZ35252.1 - 0.04 13.3 0.0 16 4.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein ATPase PF06745.13 CBZ35252.1 - 0.14 11.5 0.2 3 7.1 0.0 2.6 2 1 0 2 2 2 0 KaiC SKI PF01202.22 CBZ35252.1 - 0.14 12.2 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_29 PF13555.6 CBZ35252.1 - 0.16 11.7 0.0 7.5 6.4 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Aminotran_5 PF00266.19 CBZ35253.1 - 1.3e-83 281.1 0.0 1.5e-83 280.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBZ35253.1 - 2e-10 40.4 0.1 3e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CBZ35253.1 - 0.0016 17.8 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CBZ35253.1 - 0.011 14.5 0.1 0.02 13.7 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain AAA PF00004.29 CBZ35254.1 - 7e-37 126.8 0.0 5e-27 94.9 0.0 3.6 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ35254.1 - 5.9e-14 52.5 0.9 1.5e-06 28.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ35254.1 - 1.4e-11 45.1 0.9 0.00028 21.3 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 CBZ35254.1 - 2.5e-09 37.8 0.1 0.0012 19.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CBZ35254.1 - 9.2e-08 31.7 0.0 0.00066 19.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBZ35254.1 - 1e-07 32.0 0.0 0.0083 16.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CBZ35254.1 - 3.1e-07 30.3 0.0 0.00083 19.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 CBZ35254.1 - 8.1e-07 28.6 0.0 0.039 13.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 CBZ35254.1 - 1.1e-06 28.9 0.0 0.044 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CBZ35254.1 - 2.7e-06 27.7 0.0 0.0017 18.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CBZ35254.1 - 5.1e-06 26.3 0.1 0.0022 17.7 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CBZ35254.1 - 6.3e-06 26.4 0.0 0.00056 20.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 CBZ35254.1 - 1.8e-05 24.5 0.0 0.076 12.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 CBZ35254.1 - 2e-05 24.9 0.0 0.28 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 CBZ35254.1 - 2.6e-05 24.7 0.0 0.15 12.6 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_24 PF13479.6 CBZ35254.1 - 3.5e-05 23.6 0.0 0.22 11.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.6 CBZ35254.1 - 4.6e-05 23.8 0.0 0.15 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 CBZ35254.1 - 6.6e-05 22.3 0.0 0.34 10.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 CBZ35254.1 - 0.00022 21.6 0.0 0.74 10.2 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 CBZ35254.1 - 0.00026 20.6 0.0 0.32 10.5 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_lid_3 PF17862.1 CBZ35254.1 - 0.00047 19.9 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_29 PF13555.6 CBZ35254.1 - 0.001 18.8 0.0 0.17 11.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CBZ35254.1 - 0.001 18.7 0.1 1.7 8.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 CBZ35254.1 - 0.0013 18.9 0.0 0.64 10.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain KTI12 PF08433.10 CBZ35254.1 - 0.0021 17.5 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 NACHT PF05729.12 CBZ35254.1 - 0.0022 17.9 0.2 5.4 6.9 0.0 3.4 3 1 0 3 3 3 0 NACHT domain RuvB_N PF05496.12 CBZ35254.1 - 0.0024 17.7 0.1 0.97 9.2 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 CBZ35254.1 - 0.0024 17.1 0.0 0.45 9.6 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain TsaE PF02367.17 CBZ35254.1 - 0.003 17.6 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 CBZ35254.1 - 0.0033 17.4 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 CBZ35254.1 - 0.0041 17.1 0.0 0.69 9.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain 6PF2K PF01591.18 CBZ35254.1 - 0.0054 16.1 0.1 0.6 9.4 0.1 2.2 2 0 0 2 2 2 1 6-phosphofructo-2-kinase TniB PF05621.11 CBZ35254.1 - 0.0055 16.1 0.0 0.35 10.2 0.0 2.8 2 1 0 2 2 2 1 Bacterial TniB protein Viral_helicase1 PF01443.18 CBZ35254.1 - 0.0057 16.4 0.0 0.028 14.1 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 CBZ35254.1 - 0.011 15.6 0.0 3.6 7.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CBZ35254.1 - 0.014 15.3 0.1 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 NTPase Ploopntkinase3 PF18751.1 CBZ35254.1 - 0.034 14.1 0.0 0.13 12.2 0.0 2.0 2 0 0 2 2 1 0 P-loop Nucleotide Kinase3 T2SSE PF00437.20 CBZ35254.1 - 0.038 13.0 0.1 0.24 10.4 0.1 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein MeaB PF03308.16 CBZ35254.1 - 0.044 12.8 2.0 0.073 12.0 0.3 2.2 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 CBZ35254.1 - 0.045 12.9 0.0 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 CBZ35254.1 - 0.074 13.6 0.2 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CBZ35254.1 - 0.098 12.7 0.0 0.89 9.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase PPV_E1_C PF00519.17 CBZ35254.1 - 0.1 11.4 0.0 10 4.8 0.0 2.3 2 0 0 2 2 2 0 Papillomavirus helicase Parvo_NS1 PF01057.17 CBZ35254.1 - 0.14 11.2 0.0 5.8 5.9 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 CBZ35254.1 - 0.2 11.5 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 CBZ35254.1 - 0.38 10.1 1.0 26 4.1 0.4 2.9 2 1 1 3 3 3 0 KaiC TPR_19 PF14559.6 CBZ35255.1 - 6.8e-07 29.7 20.6 0.09 13.3 0.0 10.0 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ35255.1 - 1e-05 25.6 14.8 0.76 10.3 0.0 8.6 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ35255.1 - 1.9e-05 25.1 54.3 0.068 14.0 0.0 15.4 14 5 4 18 18 16 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ35255.1 - 2.1e-05 24.2 6.7 6.8 6.7 0.5 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ35255.1 - 0.00081 19.3 24.3 22 5.5 0.0 11.8 14 0 0 14 14 14 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ35255.1 - 0.001 18.7 2.0 5.8 6.7 0.0 5.6 7 0 0 7 7 7 1 TPR repeat TPR_12 PF13424.6 CBZ35255.1 - 0.0016 18.6 46.0 0.024 14.9 3.7 10.6 10 2 1 11 11 11 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ35255.1 - 0.0039 17.1 19.9 0.57 10.3 0.2 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ35255.1 - 0.0099 16.0 12.1 31 5.1 0.2 8.8 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ35255.1 - 0.037 14.7 0.0 0.037 14.7 0.0 11.0 12 2 1 13 13 10 0 Tetratricopeptide repeat Exonuc_VII_L PF02601.15 CBZ35255.1 - 0.18 11.4 3.6 0.66 9.5 3.6 2.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit EBP PF05241.12 CBZ35256.1 - 4.3e-14 52.4 3.7 5.3e-14 52.1 3.7 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 CBZ35256.1 - 0.00026 21.4 6.4 0.00034 21.1 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF5408 PF17402.2 CBZ35256.1 - 4.6 7.2 6.3 24 4.9 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5408) MRP PF09387.10 CBZ35258.1 - 1.3e-50 172.1 0.7 1.3e-50 172.1 0.7 1.9 2 0 0 2 2 2 1 Mitochondrial RNA binding protein MRP Neur_chan_memb PF02932.16 CBZ35258.1 - 4.6 7.2 4.9 1.2 9.1 2.2 1.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region WGG PF10273.9 CBZ35259.1 - 5.7e-06 26.9 0.6 1.6e-05 25.5 0.6 1.8 1 1 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Virul_Fac PF10139.9 CBZ35259.1 - 0.0041 15.4 0.3 0.005 15.1 0.3 1.0 1 0 0 1 1 1 1 Putative bacterial virulence factor DUF5435 PF17503.2 CBZ35259.1 - 0.035 13.8 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5435) CDC45 PF02724.14 CBZ35259.1 - 0.043 12.1 0.7 0.037 12.3 0.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TPR_16 PF13432.6 CBZ35261.1 - 2e-25 89.1 22.1 2.7e-05 24.7 0.0 7.5 6 1 3 9 9 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ35261.1 - 3.7e-25 86.7 45.9 6.5e-05 22.6 0.9 11.7 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ35261.1 - 1.7e-23 80.7 46.6 0.0011 18.9 0.3 12.0 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ35261.1 - 9.4e-19 67.5 31.9 6.1e-06 26.4 0.2 9.2 8 4 1 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ35261.1 - 2e-18 66.7 25.4 1.1e-05 25.8 1.2 7.5 6 2 3 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ35261.1 - 5.4e-18 64.4 27.7 7.7e-05 23.1 0.0 11.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ35261.1 - 1.5e-16 59.1 26.3 0.041 13.9 0.0 10.1 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ35261.1 - 1.8e-16 58.9 31.7 0.0086 16.2 0.4 10.4 12 0 0 12 12 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ35261.1 - 4.7e-14 51.9 12.6 0.015 16.1 0.0 9.3 5 3 4 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ35261.1 - 2.2e-09 36.8 28.3 3.7e-06 26.5 1.3 8.1 9 1 0 9 9 9 3 TPR repeat ANAPC3 PF12895.7 CBZ35261.1 - 5.1e-09 36.2 30.3 0.00047 20.3 0.4 7.1 5 2 4 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CBZ35261.1 - 3e-06 27.3 5.4 0.15 12.2 0.0 5.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ35261.1 - 1.1e-05 25.4 29.0 0.01 16.1 0.5 10.1 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ35261.1 - 0.00055 20.3 0.4 30 5.6 0.1 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 CBZ35261.1 - 0.00069 18.5 6.2 0.0039 16.0 0.0 2.9 3 1 1 4 4 4 1 Protein of unknown function (DUF3808) DUF4919 PF16266.5 CBZ35261.1 - 0.011 15.7 4.7 0.35 10.8 0.0 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4919) TPR_10 PF13374.6 CBZ35261.1 - 0.019 14.9 32.2 4 7.4 0.0 9.2 11 0 0 11 11 10 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBZ35261.1 - 0.073 12.7 0.2 35 4.1 0.0 3.6 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF3856 PF12968.7 CBZ35261.1 - 0.18 11.9 4.0 4.1 7.5 0.4 3.7 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) 23S_rRNA_IVP PF05635.11 CBZ35261.1 - 0.25 11.7 3.4 5.5 7.3 0.1 4.0 5 0 0 5 5 4 0 23S rRNA-intervening sequence protein PPR PF01535.20 CBZ35261.1 - 0.85 10.0 14.5 17 6.0 0.1 7.8 8 0 0 8 8 8 0 PPR repeat Fis1_TPR_C PF14853.6 CBZ35261.1 - 3.5 7.8 23.5 1.6 8.9 0.2 6.7 7 1 1 8 8 6 0 Fis1 C-terminal tetratricopeptide repeat JmjC PF02373.22 CBZ35263.1 - 1.2e-10 41.8 5.0 3.3e-09 37.2 5.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 CBZ35263.1 - 0.0019 18.0 0.0 0.067 12.9 0.0 2.7 2 1 0 2 2 2 1 Cupin-like domain HTH_Tnp_ISL3 PF13542.6 CBZ35263.1 - 0.089 12.2 0.2 0.19 11.2 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 RAI16-like PF10257.9 CBZ35264.1 - 1.7e-07 30.5 0.1 0.0014 17.6 0.0 2.8 2 1 0 3 3 3 2 Retinoic acid induced 16-like protein Arm PF00514.23 CBZ35264.1 - 0.5 10.5 2.7 0.66 10.1 0.4 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat CNDH2_M PF16869.5 CBZ35265.1 - 0.042 14.6 0.7 0.042 14.6 0.7 1.7 2 0 0 2 2 2 0 PF16858 eIF-1a PF01176.19 CBZ35265.1 - 0.075 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 SpoIIE PF07228.12 CBZ35266.1 - 0.002 18.1 1.0 0.019 14.9 0.6 2.7 1 1 1 2 2 2 1 Stage II sporulation protein E (SpoIIE) HC2 PF07382.11 CBZ35267.1 - 0.00043 20.4 33.2 0.00051 20.2 33.2 1.1 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 zf-RING_2 PF13639.6 CBZ35268.1 - 1.1e-08 35.2 14.6 3.1e-08 33.8 14.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBZ35268.1 - 3.7e-08 33.5 11.7 8.6e-08 32.4 11.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CBZ35268.1 - 2.8e-06 26.9 7.7 5.8e-06 25.9 7.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CBZ35268.1 - 1.4e-05 25.0 7.9 3.3e-05 23.8 7.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 CBZ35268.1 - 3.6e-05 23.7 4.7 7.4e-05 22.7 4.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CBZ35268.1 - 3.7e-05 23.5 11.7 3.7e-05 23.5 11.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ35268.1 - 0.00069 19.4 11.2 0.0016 18.3 11.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ35268.1 - 0.019 14.9 12.9 0.042 13.8 12.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CBZ35268.1 - 0.21 11.2 9.4 0.5 10.0 9.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 CBZ35268.1 - 0.35 10.8 5.8 10 6.1 0.0 2.7 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 CBZ35268.1 - 1.3 8.9 13.8 0.83 9.6 11.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IF-2B PF01008.17 CBZ35269.1 - 1.6e-33 116.1 0.0 4.1e-33 114.8 0.0 1.8 2 1 0 2 2 2 1 Initiation factor 2 subunit family FliD_N PF02465.18 CBZ35269.1 - 0.098 13.4 11.8 1.6 9.4 1.7 3.2 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Allexi_40kDa PF05549.11 CBZ35269.1 - 0.1 12.1 1.2 0.21 11.1 0.1 1.8 1 1 0 2 2 2 0 Allexivirus 40kDa protein UPF0449 PF15136.6 CBZ35269.1 - 0.66 10.5 2.8 6.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Com_YlbF PF06133.11 CBZ35269.1 - 1.9 9.1 8.9 13 6.5 2.0 2.5 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA IMD PF08397.11 CBZ35269.1 - 5.2 6.4 11.2 7 6.0 4.1 2.3 2 0 0 2 2 2 0 IRSp53/MIM homology domain ABC_tran_CTD PF16326.5 CBZ35269.1 - 5.4 7.3 12.6 0.12 12.7 3.3 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain NuA4 PF09340.10 CBZ35270.1 - 0.048 13.5 0.6 1.9 8.4 0.1 2.8 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 WD40 PF00400.32 CBZ35272.1 - 6.8e-16 58.4 18.2 0.00093 20.0 0.5 5.8 4 1 1 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ35272.1 - 0.00014 22.0 0.2 0.52 10.6 0.0 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CBZ35272.1 - 0.031 14.2 0.0 0.29 11.1 0.0 2.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cpn60_TCP1 PF00118.24 CBZ35273.1 - 1.6e-148 495.4 11.2 1.9e-148 495.2 11.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_efflux PF01545.21 CBZ35274.1 - 8.1e-44 149.7 15.5 8.1e-44 149.7 15.5 2.7 2 1 0 2 2 2 1 Cation efflux family UCH PF00443.29 CBZ35275.1 - 1.7e-48 165.3 0.9 2.4e-48 164.9 0.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ35275.1 - 2.3e-15 57.0 2.6 8.6e-15 55.1 2.6 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DZR PF12773.7 CBZ35275.1 - 1.2 9.3 8.5 7.5 6.7 8.6 2.1 1 1 1 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 CBZ35275.1 - 2.1 8.4 8.5 11 6.1 1.2 2.5 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Ribonucleas_3_3 PF14622.6 CBZ35277.1 - 3.7e-05 23.9 0.0 0.0016 18.6 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease-III-like vMSA PF00695.19 CBZ35277.1 - 0.037 13.1 0.1 0.047 12.8 0.1 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus LRR_6 PF13516.6 CBZ35278.1 - 5.2e-21 72.9 16.8 0.0015 18.4 0.0 9.6 10 0 0 10 10 10 7 Leucine Rich repeat LRR_1 PF00560.33 CBZ35278.1 - 4.5e-08 32.6 1.4 1.7 9.5 0.5 7.2 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_8 PF13855.6 CBZ35278.1 - 2.4e-06 27.2 1.7 0.024 14.4 0.4 5.3 5 2 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 CBZ35278.1 - 1.2e-05 25.5 7.8 0.15 12.6 0.1 5.2 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ35278.1 - 0.061 12.8 0.5 0.39 10.2 0.0 2.4 3 0 0 3 3 3 0 Leucine-rich repeat SAM_2 PF07647.17 CBZ35280.1 - 0.044 13.9 0.0 0.055 13.6 0.0 1.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) LpxI_N PF17930.1 CBZ35280.1 - 0.13 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 LpxI N-terminal domain tRNA-synt_1d PF00750.19 CBZ35281.1 - 5.3e-111 370.9 0.1 1e-66 225.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.15 CBZ35281.1 - 3e-27 95.2 2.5 4.1e-26 91.5 0.4 2.7 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CBZ35281.1 - 9.4e-14 51.8 0.2 3.3e-13 50.0 0.2 2.0 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Cupin_8 PF13621.6 CBZ35282.1 - 2.4e-16 60.2 1.3 7.7e-16 58.6 0.1 2.3 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 CBZ35282.1 - 2.7e-11 43.9 0.1 6e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 CBZ35282.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein F-box PF00646.33 CBZ35282.1 - 0.0048 16.8 0.4 0.023 14.6 0.6 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CBZ35282.1 - 0.085 12.8 0.1 0.19 11.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like Cupin_2 PF07883.11 CBZ35282.1 - 0.11 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Cupin domain LAM_C PF12544.8 CBZ35282.1 - 0.16 12.1 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Lysine-2,3-aminomutase Mo25 PF08569.11 CBZ35283.1 - 0.14 11.5 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Mo25-like Pkinase PF00069.25 CBZ35287.1 - 6.6e-58 196.1 0.0 9.7e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35287.1 - 5.4e-41 140.6 0.0 9.5e-41 139.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ35287.1 - 0.0047 16.9 0.0 0.021 14.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ35287.1 - 0.015 14.1 0.0 0.032 13.0 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CBZ35287.1 - 0.33 10.0 0.0 0.53 9.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_L10 PF00466.20 CBZ35288.1 - 4.5e-18 65.2 0.1 5.2e-18 65.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L10 DUF1719 PF08224.11 CBZ35289.1 - 0.023 13.8 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) Choline_kinase PF01633.20 CBZ35291.1 - 5.1e-20 72.0 0.1 1.6e-19 70.4 0.1 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBZ35291.1 - 2.2e-11 44.2 0.0 7e-11 42.5 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CBZ35291.1 - 0.0077 15.6 0.1 0.017 14.5 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain AlbA_2 PF04326.14 CBZ35292.1 - 0.00037 20.8 0.0 0.00065 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative DNA-binding domain Snf7 PF03357.21 CBZ35293.1 - 1.2e-33 116.1 34.7 1.2e-33 116.1 34.7 1.9 1 1 1 2 2 2 2 Snf7 CBF PF03914.17 CBZ35294.1 - 4.3e-32 111.5 1.7 7.4e-32 110.7 0.3 2.1 2 0 0 2 2 2 1 CBF/Mak21 family DUF2773 PF10971.8 CBZ35294.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) BUD22 PF09073.10 CBZ35294.1 - 3.2 7.0 12.6 5.1 6.3 12.6 1.2 1 0 0 1 1 1 0 BUD22 PCI PF01399.27 CBZ35295.1 - 4.9e-18 65.6 0.1 9.6e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.11 CBZ35295.1 - 9.4e-16 58.0 1.3 9.4e-16 58.0 1.3 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 CBZ35295.1 - 0.072 13.2 0.8 0.22 11.7 0.8 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat cNMP_binding PF00027.29 CBZ35296.1 - 6.6e-13 48.5 0.1 0.0015 18.6 0.0 4.2 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain DUF543 PF04418.12 CBZ35301.1 - 1.6e-21 76.0 0.0 2e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) GNAT_acetyltran PF12746.7 CBZ35302.1 - 3.4e-67 226.6 0.0 4.2e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 GNAT acetyltransferase RNA_pol_L_2 PF13656.6 CBZ35303.1 - 1.7e-22 79.0 0.0 2.3e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CBZ35303.1 - 2.2e-05 23.8 0.0 4.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DAGAT PF03982.13 CBZ35304.1 - 2.9e-28 98.6 0.0 5.4e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Nha1_C PF08619.10 CBZ35304.1 - 0.049 12.8 0.6 0.079 12.2 0.6 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus DAGAT PF03982.13 CBZ35305.1 - 2.9e-28 98.6 0.0 5.4e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Nha1_C PF08619.10 CBZ35305.1 - 0.049 12.8 0.6 0.079 12.2 0.6 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Aa_trans PF01490.18 CBZ35307.1 - 9.7e-58 195.8 27.9 1.2e-57 195.5 27.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ35307.1 - 2.7e-10 39.9 6.5 6e-10 38.7 6.5 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF4231 PF14015.6 CBZ35307.1 - 0.33 11.4 6.2 4 8.0 0.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) DUF1980 PF09323.10 CBZ35307.1 - 3.8 7.4 6.1 0.52 10.2 0.4 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1980) IF4E PF01652.18 CBZ35310.1 - 1e-45 155.4 0.3 1.2e-45 155.2 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.32 CBZ35311.1 - 8.9e-07 29.5 1.4 8.7 7.4 0.0 5.9 5 1 0 5 5 5 4 WD domain, G-beta repeat BRO1 PF03097.18 CBZ35312.1 - 2e-59 201.4 0.6 2e-59 201.4 0.6 2.3 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CBZ35312.1 - 2.3e-30 105.9 10.7 2.3e-30 105.9 10.7 2.6 2 1 1 3 3 3 1 ALIX V-shaped domain binding to HIV DHHA2 PF02833.14 CBZ35312.1 - 0.018 15.2 2.2 0.68 10.1 0.2 3.4 4 0 0 4 4 4 0 DHHA2 domain kleA_kleC PF17383.2 CBZ35312.1 - 0.35 11.2 7.2 14 6.1 0.1 3.3 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Baculo_PEP_C PF04513.12 CBZ35312.1 - 4.1 7.4 8.6 2.6 8.1 0.4 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Strumpellin PF10266.9 CBZ35314.1 - 0 1337.1 0.0 0 1337.0 0.0 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin ThiF PF00899.21 CBZ35315.1 - 4.3e-62 209.6 0.0 6.1e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CBZ35315.1 - 0.00098 19.6 0.0 0.0056 17.2 0.0 2.2 2 1 0 2 2 2 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 CBZ35315.1 - 0.014 15.6 0.3 0.038 14.2 0.3 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CBZ35315.1 - 0.034 14.2 0.2 0.09 12.8 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 CBZ35315.1 - 0.091 13.4 0.1 29 5.4 0.1 3.1 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CBZ35315.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Se-cys_synth_N PF12390.8 CBZ35315.1 - 2.6 8.4 5.7 4.1 7.7 0.0 3.9 4 1 0 4 4 4 0 Selenocysteine synthase N terminal LRR_9 PF14580.6 CBZ35316.1 - 0.00015 21.3 0.1 0.00032 20.2 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBZ35317.1 - 2.1e-05 24.8 0.7 6.9e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ35317.1 - 0.00045 19.9 0.3 0.00098 18.8 0.3 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 CBZ35317.1 - 0.0054 16.3 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 CBZ35317.1 - 0.018 15.0 0.1 3.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich repeat zf-CCCH PF00642.24 CBZ35317.1 - 0.097 12.6 5.9 0.056 13.4 2.6 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CBZ35317.1 - 0.12 12.5 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 CBZ35317.1 - 0.15 11.9 2.0 0.43 10.4 2.0 1.9 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ35317.1 - 0.51 10.5 6.1 0.1 12.7 1.1 2.4 2 1 0 2 2 2 0 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ35317.1 - 0.79 10.3 7.8 0.1 13.1 3.1 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger ABC2_membrane PF01061.24 CBZ35318.1 - 0.065 12.6 19.7 0.17 11.2 19.7 1.7 1 1 0 1 1 1 0 ABC-2 type transporter eRF1_2 PF03464.15 CBZ35319.1 - 6e-41 139.9 0.0 1.2e-40 138.9 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CBZ35319.1 - 1.1e-37 129.0 1.9 1.4e-37 128.6 0.5 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 CBZ35319.1 - 2.5e-12 46.9 0.0 4.2e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 CBZ35319.1 - 2e-09 37.8 0.0 3.6e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 CBZ35319.1 - 5.5e-09 36.4 0.0 8.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Vps5 PF09325.10 CBZ35321.1 - 0.13 11.7 5.3 2 7.9 5.3 2.2 1 1 0 1 1 1 0 Vps5 C terminal like AAA_6 PF12774.7 CBZ35322.1 - 2.5e-123 411.2 0.0 6e-123 410.0 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ35322.1 - 2e-112 376.2 6.3 2e-112 376.2 6.3 4.7 5 0 0 5 5 5 2 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CBZ35322.1 - 2e-61 206.9 3.9 2e-61 206.9 3.9 2.7 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 CBZ35322.1 - 4.7e-47 160.5 0.2 7.7e-46 156.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 CBZ35322.1 - 1.7e-31 109.2 0.0 3.7e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBZ35322.1 - 7.1e-31 107.0 0.0 3.1e-20 72.6 0.0 5.6 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CBZ35322.1 - 8.5e-30 103.6 0.0 2.5e-23 82.5 0.0 4.2 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 CBZ35322.1 - 6.7e-25 87.5 0.0 5.1e-24 84.6 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBZ35322.1 - 1.5e-24 86.7 9.2 3.4e-24 85.5 9.2 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 CBZ35322.1 - 6.3e-22 78.2 0.0 6.3e-22 78.2 0.0 3.5 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_16 PF13191.6 CBZ35322.1 - 1.6e-14 54.7 4.1 0.00039 20.8 0.0 7.5 6 1 1 7 7 6 2 AAA ATPase domain AAA_22 PF13401.6 CBZ35322.1 - 5e-12 46.3 1.9 0.046 14.0 0.0 6.6 6 0 0 6 6 5 3 AAA domain AAA PF00004.29 CBZ35322.1 - 1.1e-08 35.5 0.1 0.061 13.7 0.0 5.8 5 0 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CBZ35322.1 - 1.9e-07 31.1 5.6 5.5e-06 26.4 0.0 4.0 4 0 0 4 4 3 1 RsgA GTPase RNA_helicase PF00910.22 CBZ35322.1 - 1.7e-06 28.3 0.4 0.44 11.0 0.0 5.1 5 0 0 5 5 5 1 RNA helicase AAA_24 PF13479.6 CBZ35322.1 - 5.1e-05 23.1 0.1 0.12 12.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 CBZ35322.1 - 5.6e-05 23.7 4.7 0.00051 20.6 0.0 4.4 4 0 0 4 4 2 1 ABC transporter AAA_30 PF13604.6 CBZ35322.1 - 0.0001 22.1 2.2 0.023 14.4 0.0 3.6 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 CBZ35322.1 - 0.0001 22.0 0.2 0.019 14.7 0.0 3.6 4 0 0 4 4 4 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CBZ35322.1 - 0.00026 21.5 0.0 0.11 13.0 0.0 3.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CBZ35322.1 - 0.00047 20.4 7.0 0.0011 19.2 0.0 4.3 5 0 0 5 5 2 1 AAA domain T2SSE PF00437.20 CBZ35322.1 - 0.00095 18.3 0.4 0.0042 16.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 CBZ35322.1 - 0.002 18.4 4.6 0.53 10.6 0.2 4.8 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 CBZ35322.1 - 0.0078 16.4 3.6 0.087 13.0 0.0 4.5 5 0 0 5 5 4 1 AAA domain Rad17 PF03215.15 CBZ35322.1 - 0.011 15.7 0.3 0.42 10.5 0.0 3.7 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_21 PF13304.6 CBZ35322.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_lid_7 PF17867.1 CBZ35322.1 - 0.017 15.3 0.0 0.079 13.2 0.0 2.3 1 0 0 1 1 1 0 Midasin AAA lid domain KAP_NTPase PF07693.14 CBZ35322.1 - 0.025 13.8 0.0 0.13 11.5 0.0 2.3 1 0 0 1 1 1 0 KAP family P-loop domain PhoH PF02562.16 CBZ35322.1 - 0.042 13.3 0.9 0.27 10.7 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein ATPase_2 PF01637.18 CBZ35322.1 - 0.066 13.1 9.9 0.25 11.2 0.0 4.6 5 0 0 5 5 3 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 CBZ35322.1 - 0.069 13.2 0.0 0.42 10.7 0.0 2.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CBZ35322.1 - 0.12 12.2 0.1 8.3 6.1 0.0 3.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 CBZ35322.1 - 0.15 12.1 0.2 2.3 8.2 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CBZ35322.1 - 0.15 11.9 1.7 2.1 8.3 0.0 3.7 4 0 0 4 4 2 0 NACHT domain Guanylate_kin PF00625.21 CBZ35322.1 - 0.18 11.5 1.9 5.4 6.6 0.0 3.7 4 0 0 4 4 4 0 Guanylate kinase AAA_23 PF13476.6 CBZ35322.1 - 0.43 11.1 0.0 0.43 11.1 0.0 6.0 6 1 0 6 6 3 0 AAA domain PIN_3 PF13470.6 CBZ35322.1 - 2.4 9.0 4.5 4.1 8.2 0.1 3.6 3 0 0 3 3 3 0 PIN domain TBCC PF07986.12 CBZ35323.1 - 3.2e-24 85.0 4.6 6.7e-18 64.6 6.3 2.4 2 0 0 2 2 2 2 Tubulin binding cofactor C Frag1 PF10277.9 CBZ35324.1 - 5.2e-37 127.5 14.8 5.2e-37 127.5 14.8 3.4 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 CBZ35324.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 CBZ35325.1 - 2.2e-25 89.5 0.0 2.8e-17 63.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35325.1 - 1.3e-12 47.6 0.4 2.4e-12 46.7 0.4 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ35325.1 - 3.2e-08 32.8 0.4 4.7e-08 32.2 0.4 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ35325.1 - 4.2e-05 23.6 0.0 7.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ35325.1 - 0.00074 18.9 0.1 0.0014 18.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ35325.1 - 0.0015 18.2 1.0 0.0023 17.5 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 CBZ35327.1 - 2.4e-39 135.3 0.0 3.2e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35327.1 - 9.4e-17 61.1 0.0 1.4e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ35327.1 - 0.014 14.2 0.9 0.032 13.0 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase MscS_porin PF12795.7 CBZ35329.1 - 0.0013 18.4 17.9 0.0013 18.4 17.9 13.3 4 3 5 12 12 12 3 Mechanosensitive ion channel porin domain bZIP_1 PF00170.21 CBZ35329.1 - 0.021 14.9 0.2 0.23 11.6 0.0 12.9 16 1 1 17 17 17 0 bZIP transcription factor Cbl_N PF02262.16 CBZ35329.1 - 0.045 13.8 2.9 0.86 9.6 0.0 4.5 4 0 0 4 4 4 0 CBL proto-oncogene N-terminal domain 1 Apo-CII PF05355.11 CBZ35329.1 - 0.22 11.7 7.0 5.9 7.1 0.1 3.3 3 0 0 3 3 3 0 Apolipoprotein C-II YchF-GTPase_C PF06071.13 CBZ35330.1 - 1.5e-24 86.0 0.1 3.5e-24 84.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CBZ35330.1 - 9.5e-21 74.0 0.0 1.9e-20 73.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ35330.1 - 1.3e-07 31.2 0.0 2.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 CBZ35330.1 - 0.0017 18.4 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain ABC_tran PF00005.27 CBZ35330.1 - 0.0079 16.7 0.0 0.02 15.4 0.0 1.6 1 1 0 1 1 1 1 ABC transporter MeaB PF03308.16 CBZ35330.1 - 0.04 12.9 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DSPc PF00782.20 CBZ35331.1 - 2.3e-23 82.5 0.0 3.5e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ35331.1 - 0.00068 19.3 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Flagellar_rod PF05149.12 CBZ35332.1 - 2.3e-109 365.3 24.2 2.3e-109 365.3 24.2 1.8 2 0 0 2 2 2 1 Paraflagellar rod protein SH3_9 PF14604.6 CBZ35332.1 - 7.8e-13 48.1 0.0 1.7e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBZ35332.1 - 4.2e-11 42.3 0.0 7.6e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CBZ35332.1 - 6.3e-10 38.6 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Mlp PF03304.13 CBZ35332.1 - 0.0019 18.5 2.0 0.17 12.1 1.2 2.8 2 0 0 2 2 2 1 Mlp lipoprotein family Cnl2_NKP2 PF09447.10 CBZ35332.1 - 0.029 14.5 6.8 0.054 13.7 1.7 3.8 3 0 0 3 3 3 0 Cnl2/NKP2 family protein Kp4 PF09044.10 CBZ35332.1 - 0.069 13.2 0.0 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Kp4 RRT14 PF17075.5 CBZ35332.1 - 0.34 11.0 6.7 0.041 14.0 1.7 2.0 2 0 0 2 2 2 0 Regular of rDNA transcription protein 14 FKBP_N PF01346.18 CBZ35332.1 - 3 8.8 11.4 0.18 12.8 2.7 3.2 3 0 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase GSP_synth PF03738.14 CBZ35334.1 - 5e-73 246.4 0.0 6.4e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Glutathionylspermidine synthase preATP-grasp CHAP PF05257.16 CBZ35334.1 - 3.2e-11 43.7 0.0 1e-10 42.1 0.0 1.9 1 0 0 1 1 1 1 CHAP domain Mre11_DNA_bind PF04152.14 CBZ35336.1 - 2.9e-28 99.3 0.0 6.5e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CBZ35336.1 - 6.3e-14 53.0 0.2 1.3e-13 51.9 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBZ35336.1 - 0.0012 19.1 0.0 0.026 14.7 0.0 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PSD5 PF07637.11 CBZ35337.1 - 0.0081 16.5 0.0 0.049 14.0 0.0 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1595) DICT PF10069.9 CBZ35337.1 - 0.15 11.8 0.3 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system DUF846 PF05832.12 CBZ35338.1 - 1.9e-44 151.1 11.6 2.5e-44 150.7 11.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TM1586_NiRdase PF14512.6 CBZ35339.1 - 0.045 13.3 0.2 0.07 12.7 0.2 1.4 1 1 1 2 2 2 0 Putative TM nitroreductase Amastin PF07344.11 CBZ35341.1 - 0.00035 20.4 1.4 0.00035 20.4 1.4 1.8 2 0 0 2 2 2 1 Amastin surface glycoprotein DUF5562 PF17717.1 CBZ35341.1 - 0.078 12.9 0.9 0.74 9.8 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5562) Lectin_N PF03954.14 CBZ35341.1 - 0.38 10.5 0.1 0.38 10.5 0.1 1.7 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain TMEM52 PF14979.6 CBZ35341.1 - 1.9 8.4 7.2 0.72 9.8 0.5 2.5 2 0 0 2 2 2 0 Transmembrane 52 HemY_N PF07219.13 CBZ35341.1 - 2.5 8.3 4.8 14 5.9 0.2 3.0 3 0 0 3 3 3 0 HemY protein N-terminus KdpC PF02669.15 CBZ35342.1 - 0.15 11.9 1.4 0.77 9.6 0.1 2.1 1 1 0 2 2 2 0 K+-transporting ATPase, c chain Pkinase PF00069.25 CBZ35343.1 - 2e-45 155.2 0.0 6.9e-42 143.6 0.0 3.0 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35343.1 - 5.3e-23 81.6 0.0 1e-21 77.4 0.0 2.4 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ35343.1 - 2.2e-07 30.5 0.0 3.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBZ35343.1 - 0.00091 18.3 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DUF4122 PF13498.6 CBZ35343.1 - 0.0094 15.7 0.1 0.024 14.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4122) CCDC142 PF14923.6 CBZ35343.1 - 0.095 11.4 1.0 0.14 10.8 0.3 1.6 2 0 0 2 2 2 0 Coiled-coil protein 142 APH PF01636.23 CBZ35343.1 - 0.25 11.2 3.4 1.3 8.9 3.4 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family AF-4 PF05110.13 CBZ35343.1 - 2.9 5.9 12.9 5.1 5.0 12.9 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 CBZ35343.1 - 4.9 6.7 13.9 1.1 8.8 9.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dpy-30 PF05186.13 CBZ35344.1 - 4.9e-06 26.1 0.1 9.3e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif Hydin_ADK PF17213.3 CBZ35344.1 - 0.096 13.0 8.4 0.044 14.1 0.7 2.8 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Rap_GAP PF02145.15 CBZ35344.1 - 0.21 11.1 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Rap/ran-GAP IFT43 PF15305.6 CBZ35345.1 - 0.00013 22.1 6.8 0.00076 19.7 6.8 2.4 1 1 0 1 1 1 1 Intraflagellar transport protein 43 LSM PF01423.22 CBZ35346.1 - 6.8e-18 64.1 0.3 8.3e-18 63.8 0.3 1.1 1 0 0 1 1 1 1 LSM domain HA1 PF18239.1 CBZ35346.1 - 0.072 13.0 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Hemagglutinin I FtsJ PF01728.19 CBZ35347.1 - 2.5e-56 190.6 0.1 3.9e-56 190.0 0.1 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 CBZ35347.1 - 3.6e-30 105.2 18.2 3.6e-30 105.2 18.2 3.3 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 CBZ35347.1 - 2.1e-29 102.4 4.1 2.1e-29 102.4 4.1 4.7 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) TrmB PF01978.19 CBZ35347.1 - 0.019 14.9 0.3 0.058 13.3 0.3 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RabGAP-TBC PF00566.18 CBZ35348.1 - 3e-29 102.2 0.0 3.4e-15 56.3 0.0 3.6 4 0 0 4 4 4 3 Rab-GTPase-TBC domain GMP_PDE_delta PF05351.11 CBZ35349.1 - 7.9e-63 211.2 0.1 9.2e-63 211.0 0.1 1.0 1 0 0 1 1 1 1 GMP-PDE, delta subunit BRE1 PF08647.11 CBZ35350.1 - 0.0059 16.6 1.6 0.0091 16.0 1.6 1.2 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase Cgr1 PF03879.14 CBZ35350.1 - 0.25 11.7 6.1 0.4 11.1 6.1 1.2 1 0 0 1 1 1 0 Cgr1 family FOXP-CC PF16159.5 CBZ35350.1 - 1.2 9.8 5.2 3.1 8.5 5.0 1.8 1 1 0 1 1 1 0 FOXP coiled-coil domain FAD-oxidase_C PF02913.19 CBZ35351.1 - 3.1e-38 131.9 0.1 4.5e-38 131.3 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBZ35351.1 - 1.6e-34 118.6 2.1 3.8e-34 117.4 2.1 1.7 1 0 0 1 1 1 1 FAD binding domain Aminotran_4 PF01063.19 CBZ35352.1 - 8.2e-28 97.8 0.0 1.1e-27 97.4 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Erv26 PF04148.13 CBZ35353.1 - 3.6e-19 69.4 11.9 3.9e-18 66.0 11.9 1.9 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Ribonuc_red_sm PF00268.21 CBZ35354.1 - 2.7e-48 164.8 0.5 3.2e-48 164.6 0.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain OCRE PF17780.1 CBZ35356.1 - 5.7e-05 23.1 2.7 0.00014 21.8 2.7 1.6 1 0 0 1 1 1 1 OCRE domain Comm PF15957.5 CBZ35356.1 - 4.2 7.7 5.7 9.5 6.6 4.5 2.2 2 0 0 2 2 2 0 Commissureless RRM_1 PF00076.22 CBZ35359.1 - 6.9e-34 115.5 0.0 2.8e-11 43.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ35359.1 - 3.2e-10 39.8 0.1 0.0064 16.5 0.0 3.3 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CBZ35359.1 - 1.2e-07 31.5 0.0 0.0018 18.1 0.0 2.6 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 CBZ35359.1 - 0.00046 20.3 0.1 0.51 10.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif zf-CCHC PF00098.23 CBZ35359.1 - 0.00078 19.4 0.5 0.0015 18.5 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_3 PF08777.11 CBZ35359.1 - 0.013 15.5 0.0 24 5.0 0.0 3.4 3 0 0 3 3 3 0 RNA binding motif zf-CCHC_3 PF13917.6 CBZ35359.1 - 0.034 14.1 1.7 0.082 12.9 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle PHM7_cyt PF14703.6 CBZ35359.1 - 0.065 13.5 0.1 8.7 6.5 0.0 3.3 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Lipase_3 PF01764.25 CBZ35360.1 - 2.7e-13 50.0 0.0 7e-12 45.4 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) C1_1 PF00130.22 CBZ35360.1 - 0.00016 21.5 3.4 0.0088 15.9 0.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Hydrolase_4 PF12146.8 CBZ35360.1 - 0.013 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 C1_2 PF03107.16 CBZ35360.1 - 0.031 14.6 0.7 0.12 12.7 0.1 2.2 2 0 0 2 2 2 0 C1 domain Zf_RING PF16744.5 CBZ35360.1 - 0.16 12.1 4.3 0.064 13.4 0.8 2.1 2 0 0 2 2 2 0 KIAA1045 RING finger zf-RING-like PF08746.11 CBZ35360.1 - 0.26 11.6 5.4 0.64 10.4 2.1 2.4 2 0 0 2 2 2 0 RING-like domain Motile_Sperm PF00635.26 CBZ35361.1 - 1.9e-06 27.7 0.2 6.8e-06 25.9 0.0 2.0 2 1 0 2 2 2 1 MSP (Major sperm protein) domain SOG2 PF10428.9 CBZ35361.1 - 0.27 10.4 3.9 0.31 10.2 3.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PI3_PI4_kinase PF00454.27 CBZ35363.1 - 6.3e-19 68.8 0.0 2.5e-18 66.8 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase WD40 PF00400.32 CBZ35366.1 - 1.1e-11 45.1 2.7 0.0071 17.2 0.1 6.8 8 0 0 8 8 8 3 WD domain, G-beta repeat BORCS6 PF10157.9 CBZ35366.1 - 0.045 14.0 0.1 0.045 14.0 0.1 2.9 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 6 Ge1_WD40 PF16529.5 CBZ35366.1 - 0.067 12.2 0.4 0.18 10.7 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NIF PF03031.18 CBZ35367.1 - 9.5e-26 90.4 0.0 1.4e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase VKOR PF07884.14 CBZ35368.1 - 3.1e-17 62.9 19.8 3.7e-17 62.7 19.8 1.1 1 0 0 1 1 1 1 Vitamin K epoxide reductase family Thioredoxin PF00085.20 CBZ35369.1 - 2.3e-06 27.5 0.0 4.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 CBZ35369.1 - 2.6e-05 23.3 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Phosducin DSPc PF00782.20 CBZ35370.1 - 3.2e-25 88.5 0.0 4.6e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ35370.1 - 0.0096 15.5 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ribosomal_L11_N PF03946.14 CBZ35371.1 - 1.7e-15 56.6 0.0 3e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CBZ35371.1 - 6.7e-15 55.4 0.0 1.2e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Atg14 PF10186.9 CBZ35373.1 - 5.6e-06 25.7 3.3 8.8e-06 25.0 3.3 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TFIIA PF03153.13 CBZ35373.1 - 1.3 8.9 4.9 2 8.3 4.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FTA4 PF13093.6 CBZ35373.1 - 3.8 7.3 11.1 5.9 6.7 11.1 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DivIC PF04977.15 CBZ35373.1 - 4.7 7.1 10.5 1.4 8.8 0.1 2.7 2 0 0 2 2 2 0 Septum formation initiator EMG1 PF03587.14 CBZ35374.1 - 3.6e-39 134.4 0.0 4.5e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF5372 PF17342.2 CBZ35375.1 - 0.76 10.2 9.2 0.076 13.4 1.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5372) Tropomyosin PF00261.20 CBZ35376.1 - 0.036 13.4 0.4 0.066 12.6 0.4 1.4 1 0 0 1 1 1 0 Tropomyosin Mcp5_PH PF12814.7 CBZ35377.1 - 1e-15 57.9 0.1 1.3e-15 57.6 0.1 1.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 CBZ35377.1 - 2.5e-07 31.1 0.5 3e-07 30.9 0.5 1.1 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 CBZ35377.1 - 0.046 14.1 0.5 0.067 13.6 0.0 1.5 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_12 PF16457.5 CBZ35377.1 - 0.063 13.8 0.6 0.42 11.1 0.6 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain ACOX PF01756.19 CBZ35378.1 - 9e-10 38.4 0.0 2.2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Spt5-NGN PF03439.13 CBZ35379.1 - 2.5e-21 75.3 0.4 8.1e-21 73.7 0.1 2.1 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CBZ35379.1 - 1.8e-06 27.7 5.4 0.076 13.0 0.1 4.2 4 0 0 4 4 4 2 KOW motif HAS-barrel PF09378.10 CBZ35379.1 - 0.0015 18.7 0.3 0.51 10.5 0.0 3.3 3 0 0 3 3 3 1 HAS barrel domain Hormone_3 PF00159.18 CBZ35379.1 - 0.0083 16.2 2.2 0.18 11.9 0.3 2.7 2 0 0 2 2 2 1 Pancreatic hormone peptide BUD22 PF09073.10 CBZ35379.1 - 1.2 8.4 16.4 1.9 7.8 16.4 1.2 1 0 0 1 1 1 0 BUD22 MORN PF02493.20 CBZ35380.1 - 3.2e-21 73.9 19.0 1.4e-07 31.0 0.1 5.9 6 0 0 6 6 6 4 MORN repeat PP2C PF00481.21 CBZ35382.1 - 1.6e-76 257.4 0.0 1.9e-76 257.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SCRL PF06876.12 CBZ35382.1 - 0.062 13.5 0.2 0.19 12.0 0.2 1.8 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein YchF-GTPase_C PF06071.13 CBZ35383.1 - 3.3e-37 126.5 0.4 8e-37 125.3 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CBZ35383.1 - 4.6e-22 78.3 0.0 2.6e-21 75.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ35383.1 - 9.3e-05 22.0 0.0 0.00023 20.7 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 CBZ35383.1 - 0.013 16.0 0.0 0.051 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CBZ35383.1 - 0.026 14.7 0.0 0.52 10.5 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 CBZ35383.1 - 0.029 13.4 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TGS PF02824.21 CBZ35383.1 - 0.031 14.3 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 TGS domain ABC_tran PF00005.27 CBZ35383.1 - 0.092 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 CBZ35383.1 - 0.16 12.0 0.1 25 4.9 0.0 2.6 1 1 1 2 2 2 0 Dynamin family DUF5526 PF17664.1 CBZ35384.1 - 0.069 12.7 0.8 0.089 12.3 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5526) Cpn60_TCP1 PF00118.24 CBZ35385.1 - 0.018 13.7 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family Glyco_hydro_32N PF00251.20 CBZ35386.1 - 7.2e-82 275.4 3.0 8.7e-82 275.1 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CBZ35386.1 - 1e-20 74.3 0.0 1.5e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal RcnB PF11776.8 CBZ35386.1 - 0.042 13.9 1.7 1.9 8.6 0.0 3.2 3 0 0 3 3 3 0 Nickel/cobalt transporter regulator Synaptobrevin PF00957.21 CBZ35387.1 - 2.5e-23 81.7 0.5 3.4e-23 81.2 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CBZ35387.1 - 1.8e-10 40.7 0.1 3.3e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain HHV-5_US34A PF17087.5 CBZ35389.1 - 0.028 14.6 3.4 0.066 13.4 2.4 2.2 2 1 0 2 2 2 0 Herpesvirus US34A protein family GWT1 PF06423.12 CBZ35390.1 - 0.23 11.6 5.3 0.27 11.3 5.3 1.3 1 1 0 1 1 1 0 GWT1 TPR_2 PF07719.17 CBZ35391.1 - 1.6e-14 52.7 4.1 7.3e-05 22.6 1.9 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ35391.1 - 3.6e-14 51.9 3.5 2.9e-05 23.7 0.8 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat RPAP3_C PF13877.6 CBZ35391.1 - 9.7e-14 51.7 0.1 1.9e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_8 PF13181.6 CBZ35391.1 - 1.1e-09 37.7 3.3 0.00079 19.5 0.4 4.2 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ35391.1 - 7.2e-07 28.8 6.2 0.00023 20.8 0.0 4.2 4 2 2 6 6 6 2 TPR repeat TPR_16 PF13432.6 CBZ35391.1 - 1.7e-05 25.4 8.8 0.00028 21.5 2.7 4.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ35391.1 - 4.3e-05 23.6 1.6 0.52 10.8 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ35391.1 - 5.7e-05 23.3 5.4 0.012 15.9 4.5 3.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ35391.1 - 0.00022 21.7 4.8 0.0056 17.4 3.3 4.9 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ35391.1 - 0.00032 20.8 25.9 0.00059 19.9 1.2 4.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ35391.1 - 0.0014 19.1 14.4 0.0026 18.2 0.1 3.5 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ35391.1 - 0.082 13.6 14.6 0.12 13.1 1.3 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ35391.1 - 0.088 12.9 6.8 16 5.8 0.4 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ35391.1 - 0.12 12.6 3.5 0.81 10.0 3.4 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SMYLE_N PF18615.1 CBZ35391.1 - 0.69 9.4 20.0 0.25 10.8 17.2 1.6 1 1 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF3808 PF10300.9 CBZ35391.1 - 1.4 7.6 8.1 0.12 11.1 1.5 2.3 1 1 1 3 3 3 0 Protein of unknown function (DUF3808) GREB1 PF15782.5 CBZ35391.1 - 5.8 3.9 14.0 7.7 3.5 14.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DnaJ_C PF01556.18 CBZ35392.1 - 4.6e-32 111.1 0.0 6.1e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ35392.1 - 2.4e-28 98.0 0.7 2.4e-28 98.0 0.7 1.8 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ35392.1 - 1.9e-13 50.6 16.8 3.1e-13 49.9 16.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ35392.1 - 0.0051 16.7 8.1 0.5 10.4 1.6 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CBZ35392.1 - 2.3 8.3 11.0 2.6 8.1 1.3 2.6 1 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CBZ35392.1 - 5.6 7.1 12.1 4.9e+02 0.9 12.2 2.6 1 1 0 1 1 1 0 Double zinc ribbon Aldo_ket_red PF00248.21 CBZ35393.1 - 7.6e-33 113.9 0.0 1.6e-32 112.9 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family TBPIP PF07106.13 CBZ35394.1 - 1.1e-08 34.8 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Nore1-SARAH PF16517.5 CBZ35394.1 - 0.15 12.0 2.4 0.15 12.0 0.6 1.8 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain adh_short_C2 PF13561.6 CBZ35396.1 - 7e-42 143.6 0.7 7.9e-42 143.4 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CBZ35396.1 - 5.2e-38 130.5 0.5 7.4e-38 130.0 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CBZ35396.1 - 1e-14 54.9 1.7 4.3e-14 52.8 1.7 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ35396.1 - 2.8e-06 27.0 0.1 6.3e-06 25.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CBZ35396.1 - 0.017 14.2 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 CBZ35396.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.6 1 1 0 1 1 1 0 NAD(P)H-binding NAD_binding_4 PF07993.12 CBZ35396.1 - 0.035 13.3 0.0 6.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DUF1043 PF06295.12 CBZ35397.1 - 0.0002 21.4 6.4 0.025 14.6 0.1 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1043) AIP3 PF03915.13 CBZ35397.1 - 0.0031 16.7 1.2 0.17 10.9 0.1 2.2 2 0 0 2 2 2 2 Actin interacting protein 3 Filament PF00038.21 CBZ35397.1 - 0.071 12.7 8.6 0.63 9.6 0.6 2.3 2 0 0 2 2 2 0 Intermediate filament protein DUF724 PF05266.14 CBZ35397.1 - 0.15 11.8 2.1 0.35 10.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Prefoldin_2 PF01920.20 CBZ35397.1 - 0.35 10.9 4.0 3.7 7.5 0.0 3.4 2 1 1 3 3 3 0 Prefoldin subunit APG6_N PF17675.1 CBZ35397.1 - 1.4 9.4 6.9 0.68 10.5 2.0 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 CBZ35397.1 - 1.9 8.9 7.5 13 6.2 0.5 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) LOH1CR12 PF10158.9 CBZ35397.1 - 2.5 8.1 8.8 0.33 11.0 1.3 2.9 2 2 1 4 4 4 0 Tumour suppressor protein GAS PF13851.6 CBZ35397.1 - 5.7 6.2 7.1 2.4 7.5 0.8 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding V-SNARE PF05008.15 CBZ35397.1 - 6.8 7.2 6.8 15 6.1 0.6 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Pkinase PF00069.25 CBZ35398.1 - 3.2e-49 167.6 0.0 6e-49 166.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35398.1 - 4.6e-23 81.8 0.0 8.8e-23 80.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ35398.1 - 0.00012 22.2 0.9 0.19 11.6 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ35398.1 - 0.00055 19.3 0.0 0.64 9.3 0.0 2.9 2 1 0 3 3 3 2 Kinase-like Kdo PF06293.14 CBZ35398.1 - 0.0026 17.2 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBZ35398.1 - 0.25 10.1 0.0 0.35 9.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CBZ35399.1 - 7.2e-68 228.8 0.0 1.3e-67 227.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35399.1 - 6e-31 107.7 0.0 9.1e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ35399.1 - 0.00053 19.4 0.0 0.0026 17.1 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CBZ35399.1 - 0.053 12.9 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ35399.1 - 0.13 12.2 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 CBZ35399.1 - 0.17 11.5 0.1 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Prp19 PF08606.11 CBZ35400.1 - 2.5e-24 85.0 0.2 5.3e-24 84.0 0.2 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 CBZ35400.1 - 2.5e-09 37.6 10.5 0.051 14.5 0.7 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-Nse PF11789.8 CBZ35400.1 - 0.0011 18.7 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 CBZ35400.1 - 0.0013 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 U-box domain PALB2_WD40 PF16756.5 CBZ35400.1 - 0.017 14.0 0.3 0.11 11.4 0.0 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 CBZ35400.1 - 0.064 12.2 1.8 0.73 8.7 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 CBZ35400.1 - 0.21 9.9 0.1 2.1 6.5 0.0 2.4 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz TTL PF03133.15 CBZ35401.1 - 1.3e-48 165.6 0.0 1.9e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ35401.1 - 1.1e-05 24.8 0.0 0.26 10.5 0.0 3.2 1 1 1 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBZ35401.1 - 0.019 14.2 0.0 0.079 12.2 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 CBZ35401.1 - 0.05 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Kri1 PF05178.12 CBZ35402.1 - 0.077 13.6 4.6 0.12 12.9 4.6 1.3 1 0 0 1 1 1 0 KRI1-like family AAA_6 PF12774.7 CBZ35403.1 - 4.5e-156 518.9 0.1 2.6e-154 513.0 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ35403.1 - 1.5e-114 383.3 8.1 1.5e-114 383.3 8.1 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CBZ35403.1 - 4.4e-111 371.0 0.0 1.4e-110 369.3 0.0 1.9 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBZ35403.1 - 8e-93 310.5 0.0 2.3e-92 309.0 0.0 1.9 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CBZ35403.1 - 3e-76 255.0 0.0 3.8e-73 244.9 0.0 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_9 PF12781.7 CBZ35403.1 - 4.3e-75 251.6 2.8 1.1e-74 250.3 2.8 1.8 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 CBZ35403.1 - 5.2e-59 198.7 0.0 1.7e-58 197.1 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ35403.1 - 3.2e-39 133.7 0.0 4.2e-36 123.6 0.0 3.0 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBZ35403.1 - 8.8e-24 84.2 11.8 2.5e-23 82.7 11.7 1.8 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CBZ35403.1 - 9.4e-20 71.0 0.0 3.2e-19 69.3 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBZ35403.1 - 2e-19 70.0 0.0 4.3e-05 23.5 0.0 5.8 4 2 1 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CBZ35403.1 - 1.2e-13 51.1 0.0 3.8e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CBZ35403.1 - 1.3e-08 35.4 2.9 0.0045 17.4 0.0 4.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ35403.1 - 3.1e-08 34.0 4.4 0.037 14.3 0.0 6.2 6 0 0 6 6 5 2 AAA domain AAA_18 PF13238.6 CBZ35403.1 - 0.00012 22.6 1.3 0.01 16.4 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CBZ35403.1 - 0.00034 20.4 4.9 0.13 12.0 0.0 3.9 3 0 0 3 3 3 2 AAA domain LBR_tudor PF09465.10 CBZ35403.1 - 0.0031 17.3 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain DUF815 PF05673.13 CBZ35403.1 - 0.014 14.6 0.0 0.055 12.6 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 CBZ35403.1 - 0.029 14.4 2.4 1.2 9.2 0.1 3.6 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CBZ35403.1 - 0.033 14.4 0.1 3.8 7.7 0.0 3.9 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 CBZ35403.1 - 0.062 13.2 0.4 0.29 11.0 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.22 CBZ35403.1 - 0.066 13.6 4.2 3.3 8.2 0.0 3.7 4 0 0 4 4 3 0 RNA helicase AAA_16 PF13191.6 CBZ35403.1 - 1.4 9.3 0.0 1.4 9.3 0.0 7.9 10 0 0 10 10 8 0 AAA ATPase domain HTH_9 PF08221.11 CBZ35404.1 - 0.00055 20.0 0.1 0.021 14.9 0.0 2.9 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain HTH_9 PF08221.11 CBZ35405.1 - 0.00054 20.0 0.1 0.021 14.9 0.0 2.9 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain RL10P_insert PF17777.1 CBZ35406.1 - 2.3e-19 69.1 0.2 3.8e-19 68.4 0.2 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CBZ35406.1 - 4.7e-17 62.0 0.1 1e-16 60.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 CBZ35406.1 - 2.9e-15 56.6 4.4 2.9e-15 56.6 4.4 2.3 3 0 0 3 3 3 1 60s Acidic ribosomal protein PEPCK_ATP PF01293.20 CBZ35407.1 - 5.8e-194 645.1 0.0 7.6e-194 644.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF4914 PF16260.5 CBZ35407.1 - 0.02 13.0 0.1 0.056 11.5 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4914) AAA_33 PF13671.6 CBZ35407.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Methyltransf_25 PF13649.6 CBZ35408.1 - 0.076 13.7 0.0 0.21 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.29 CBZ35410.1 - 8.8e-09 35.9 0.0 1.1e-07 32.4 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ35410.1 - 2.9e-07 30.8 0.0 4.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ35410.1 - 3e-05 24.5 0.0 0.00024 21.5 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 CBZ35410.1 - 0.0016 18.8 0.2 0.0085 16.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBZ35410.1 - 0.0025 16.9 0.0 0.01 14.9 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 CBZ35410.1 - 0.019 14.7 0.0 0.062 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CBZ35410.1 - 0.036 14.0 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 CBZ35410.1 - 0.036 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 CBZ35410.1 - 0.086 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.15 CBZ35410.1 - 0.09 12.8 0.0 0.23 11.4 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CBZ35410.1 - 0.12 11.8 0.0 0.41 10.1 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 CBZ35410.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PPR PF01535.20 CBZ35411.1 - 4.1e-05 23.5 0.3 0.3 11.4 0.0 5.7 7 0 0 7 7 7 1 PPR repeat PPR_2 PF13041.6 CBZ35411.1 - 0.027 14.7 1.7 1.2 9.4 0.0 4.1 5 0 0 5 5 5 0 PPR repeat family DUF1168 PF06658.12 CBZ35411.1 - 0.03 14.1 0.2 0.03 14.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) NYD-SP28 PF14772.6 CBZ35412.1 - 8.2e-19 67.5 3.9 8.2e-19 67.5 3.9 4.6 2 1 1 3 3 3 1 Sperm tail NYD-SP28_assoc PF14775.6 CBZ35412.1 - 0.00025 21.1 1.5 0.0014 18.7 1.5 2.4 1 0 0 1 1 1 1 Sperm tail C-terminal domain BAG6 PF12057.8 CBZ35412.1 - 0.011 15.4 0.9 0.1 12.3 0.1 2.7 2 1 1 3 3 3 0 BCL2-associated athanogene 6 DUF5069 PF16798.5 CBZ35412.1 - 0.012 15.8 3.4 0.042 14.1 2.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5069) Hemocyanin_M PF00372.19 CBZ35412.1 - 0.27 10.4 3.7 2.5 7.2 0.7 2.3 1 1 1 2 2 2 0 Hemocyanin, copper containing domain SOAR PF16533.5 CBZ35412.1 - 2.4 8.2 22.1 0.75 9.8 1.1 3.7 1 1 1 3 3 3 0 STIM1 Orai1-activating region Baculo_PEP_C PF04513.12 CBZ35412.1 - 3.8 7.5 9.4 23 5.0 0.6 4.0 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.12 CBZ35412.1 - 4.8 7.5 15.0 0.14 12.4 1.8 4.2 2 1 2 4 4 4 0 Proteins of 100 residues with WXG IMD PF08397.11 CBZ35412.1 - 8.9 5.6 22.9 0.24 10.7 5.4 3.4 1 1 2 3 3 3 0 IRSp53/MIM homology domain CVNH PF08881.10 CBZ35412.1 - 9.7 6.9 7.9 2.3e+02 2.6 6.2 3.1 2 1 0 2 2 2 0 CVNH domain FIST PF08495.10 CBZ35413.1 - 0.00078 19.5 0.2 0.0018 18.3 0.2 1.7 1 0 0 1 1 1 1 FIST N domain IQ PF00612.27 CBZ35415.1 - 2.1e-05 23.9 15.4 0.45 10.4 0.0 5.1 4 0 0 4 4 4 4 IQ calmodulin-binding motif Guanylate_cyc PF00211.20 CBZ35416.1 - 3.3e-24 85.5 0.0 7.6e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Globin PF00042.22 CBZ35416.1 - 5.3e-11 43.1 0.2 1.8e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 Globin Proteasome PF00227.26 CBZ35418.1 - 8.6e-39 133.0 0.0 9.8e-39 132.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RNA_POL_M_15KD PF02150.16 CBZ35419.1 - 0.00041 20.2 6.5 0.00041 20.2 6.5 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CBZ35419.1 - 0.0027 17.5 3.3 0.0027 17.5 3.3 3.2 3 2 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-Sec23_Sec24 PF04810.15 CBZ35419.1 - 0.018 15.1 3.9 0.018 15.1 3.9 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger HNH_5 PF14279.6 CBZ35419.1 - 0.036 13.9 4.7 0.23 11.3 0.0 2.7 3 0 0 3 3 3 0 HNH endonuclease Ogr_Delta PF04606.12 CBZ35419.1 - 0.048 13.7 1.7 0.048 13.7 1.7 2.5 2 2 0 2 2 2 0 Ogr/Delta-like zinc finger Lar_restr_allev PF14354.6 CBZ35419.1 - 0.06 13.7 2.5 0.06 13.7 2.5 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 CBZ35419.1 - 0.14 11.7 11.7 1.2 8.6 1.1 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 CBZ35419.1 - 7.8 6.4 14.2 0.35 10.6 0.7 3.3 2 1 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CBZ35419.1 - 9.8 6.2 16.0 0.27 11.3 1.7 2.9 2 2 0 2 2 2 0 Transposase zinc-ribbon domain 7tm_1 PF00001.21 CBZ35420.1 - 0.085 12.2 0.9 0.14 11.5 0.8 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Fumble PF03630.14 CBZ35421.1 - 1.9e-94 316.5 0.0 2.8e-94 316.0 0.0 1.2 1 0 0 1 1 1 1 Fumble AMP-binding PF00501.28 CBZ35421.1 - 1.1e-15 57.2 0.6 5.6e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Exo_endo_phos PF03372.23 CBZ35421.1 - 7.6e-08 32.2 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 CBZ35422.1 - 1.3e-33 116.4 59.7 4.8e-26 91.5 35.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ35422.1 - 0.067 12.0 33.9 1.6 7.5 33.7 3.1 1 1 0 1 1 1 0 Sugar (and other) transporter RRM_1 PF00076.22 CBZ35423.1 - 0.0088 15.8 0.0 0.08 12.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.6 CBZ35423.1 - 0.023 14.3 0.0 0.058 13.0 0.0 1.6 2 0 0 2 2 2 0 Sporulation protein family 7 RRM_occluded PF16842.5 CBZ35423.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.8 1 1 0 1 1 1 0 Occluded RNA-recognition motif DSPc PF00782.20 CBZ35424.1 - 5e-26 91.1 0.0 7.7e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 CBZ35424.1 - 5.4e-09 35.7 13.3 0.00011 21.9 4.3 3.6 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CBZ35424.1 - 3.9e-05 23.9 14.4 0.0051 17.2 7.2 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) Y_phosphatase PF00102.27 CBZ35424.1 - 0.003 17.2 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_9 PF14580.6 CBZ35424.1 - 0.027 14.0 4.2 1.8 8.1 1.1 2.5 3 0 0 3 3 3 0 Leucine-rich repeat CDKN3 PF05706.12 CBZ35424.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Histone PF00125.24 CBZ35428.1 - 4.2e-11 43.3 0.1 5.4e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CBZ35428.1 - 0.013 15.8 0.3 0.023 15.0 0.3 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DHHC PF01529.20 CBZ35429.1 - 1.1e-31 109.7 3.5 1.1e-31 109.7 3.5 2.0 2 1 0 2 2 2 1 DHHC palmitoyltransferase DAO PF01266.24 CBZ35431.1 - 1.8e-43 149.5 0.1 5.2e-43 148.0 0.0 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase DAO_C PF16901.5 CBZ35431.1 - 3.3e-32 111.0 0.1 6.3e-32 110.1 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_oxidored PF12831.7 CBZ35431.1 - 0.056 12.8 1.5 0.097 12.0 1.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBZ35431.1 - 0.056 12.7 0.1 0.33 10.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CBZ35431.1 - 0.06 13.2 0.2 0.13 12.1 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 CBZ35431.1 - 0.1 11.7 1.4 0.23 10.5 1.4 1.6 1 0 0 1 1 1 0 FAD binding domain dsrm PF00035.26 CBZ35431.1 - 0.15 12.8 0.1 0.33 11.7 0.1 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif AlaDh_PNT_C PF01262.21 CBZ35431.1 - 0.18 11.1 0.0 0.18 11.1 0.0 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Carboxyl_trans PF01039.22 CBZ35432.1 - 4.9e-176 586.2 0.1 5.7e-176 586.0 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBZ35432.1 - 0.0004 19.9 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) ACCA PF03255.14 CBZ35432.1 - 0.13 12.1 0.9 2 8.3 0.0 2.5 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carboxyl_trans PF01039.22 CBZ35433.1 - 4.9e-176 586.2 0.1 5.7e-176 586.0 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 CBZ35433.1 - 0.0004 19.9 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) ACCA PF03255.14 CBZ35433.1 - 0.13 12.1 0.9 2 8.3 0.0 2.5 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Carb_anhydrase PF00194.21 CBZ35435.1 - 5.2e-27 95.0 0.0 7.3e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase VIT1 PF01988.19 CBZ35435.1 - 0.064 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 VIT family RIFIN PF02009.16 CBZ35435.1 - 0.23 11.3 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Rifin Dicty_REP PF05086.12 CBZ35435.1 - 0.38 8.7 2.0 0.54 8.2 2.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Apt1 PF10351.9 CBZ35435.1 - 2.1 7.1 6.0 2.8 6.7 6.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain WD40 PF00400.32 CBZ35436.1 - 0.0058 17.5 1.9 8.9 7.4 0.1 4.6 4 1 1 5 5 5 2 WD domain, G-beta repeat Med3 PF11593.8 CBZ35437.1 - 9.9 5.2 14.1 2.3 7.3 7.4 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal RNB PF00773.19 CBZ35438.1 - 4e-91 305.7 0.0 7.2e-91 304.9 0.0 1.4 1 1 0 1 1 1 1 RNB domain Carn_acyltransf PF00755.20 CBZ35439.1 - 0.0016 17.2 0.0 0.0032 16.2 0.0 1.4 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rft-1 PF04506.13 CBZ35442.1 - 0.06 12.1 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 Rft protein AAA PF00004.29 CBZ35443.1 - 6.2e-40 136.7 0.0 1.3e-39 135.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ35443.1 - 2.8e-10 39.8 0.0 8.8e-10 38.2 0.0 2.0 1 1 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CBZ35443.1 - 2.5e-08 33.8 0.5 8e-08 32.2 0.3 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CBZ35443.1 - 1.8e-05 24.6 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBZ35443.1 - 0.00025 21.1 0.0 0.0021 18.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) NACHT PF05729.12 CBZ35443.1 - 0.00097 19.1 0.1 0.16 11.9 0.0 2.7 3 0 0 3 3 2 1 NACHT domain Mg_chelatase PF01078.21 CBZ35443.1 - 0.0012 18.3 0.1 0.0026 17.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CBZ35443.1 - 0.0019 18.5 0.1 0.024 14.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ35443.1 - 0.0022 18.4 0.0 0.0056 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CBZ35443.1 - 0.004 16.9 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBZ35443.1 - 0.0048 16.9 0.0 0.014 15.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CBZ35443.1 - 0.0067 16.6 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CBZ35443.1 - 0.007 16.5 0.0 0.029 14.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) ATPase PF06745.13 CBZ35443.1 - 0.0098 15.3 0.0 2.6 7.3 0.0 2.6 2 1 1 3 3 3 1 KaiC TIP49 PF06068.13 CBZ35443.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 CBZ35443.1 - 0.013 16.0 0.3 0.042 14.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 CBZ35443.1 - 0.015 15.0 0.0 0.041 13.6 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CBZ35443.1 - 0.018 14.7 0.2 0.35 10.4 0.1 2.4 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBZ35443.1 - 0.025 14.9 0.0 0.066 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CBZ35443.1 - 0.026 14.1 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 CBZ35443.1 - 0.074 12.2 0.0 0.39 9.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 CBZ35443.1 - 0.089 11.9 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 CBZ35443.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 CBZ35443.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CBZ35443.1 - 0.17 11.5 0.0 0.67 9.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain FYVE PF01363.21 CBZ35444.1 - 0.035 14.2 3.6 0.71 10.1 0.4 3.0 2 0 0 2 2 2 0 FYVE zinc finger PI-TkoII_IV PF18714.1 CBZ35444.1 - 0.11 11.9 0.7 0.31 10.5 0.2 2.0 2 0 0 2 2 2 0 DNA polymerase II intein Domain IV PAPS_reduct PF01507.19 CBZ35446.1 - 6.3e-24 84.9 0.0 3.7e-21 75.9 0.0 2.1 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 CBZ35446.1 - 0.0097 15.7 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 PP-loop family zf_CCCH_4 PF18345.1 CBZ35449.1 - 7.6e-07 29.0 12.0 0.0013 18.7 3.8 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-HIT PF04438.16 CBZ35449.1 - 2.2e-06 27.4 10.8 5.8e-06 26.1 10.8 1.7 1 0 0 1 1 1 1 HIT zinc finger zf-CCCH PF00642.24 CBZ35449.1 - 5.5e-05 23.0 10.6 0.00018 21.3 1.2 2.8 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBZ35449.1 - 0.00047 20.8 4.6 0.038 14.7 0.2 2.7 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 CBZ35449.1 - 0.28 11.7 10.3 1.2 9.7 2.8 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CBZ35449.1 - 0.38 11.0 5.8 0.55 10.5 0.5 2.6 1 1 1 2 2 2 0 Zinc-finger containing family RNB PF00773.19 CBZ35452.1 - 3.3e-96 322.4 0.0 5.6e-96 321.7 0.0 1.3 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CBZ35452.1 - 1.7e-20 72.8 0.0 3.6e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 CBZ35452.1 - 7.2e-07 29.0 0.0 1.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 CBZ35452.1 - 1.1e-06 28.7 0.0 5.1e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 Cold shock domain Rrp44_S1 PF17215.3 CBZ35452.1 - 0.00083 19.3 0.1 0.0029 17.5 0.1 2.0 1 1 0 1 1 1 1 S1 domain Dis3l2_C_term PF17877.1 CBZ35452.1 - 0.014 15.7 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal MtN3_slv PF03083.16 CBZ35454.1 - 1.5e-18 66.6 11.5 7.6e-11 41.9 3.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange Tox-ODYAM1 PF15642.6 CBZ35454.1 - 0.0029 16.7 0.1 0.0039 16.2 0.1 1.1 1 0 0 1 1 1 1 Toxin in Odyssella and Amoebophilus ThiF PF00899.21 CBZ35455.1 - 5.6e-10 39.0 0.2 9.6e-10 38.2 0.2 1.4 1 0 0 1 1 1 1 ThiF family Nab1 PF04902.12 CBZ35455.1 - 0.044 14.2 0.1 0.071 13.5 0.1 1.3 1 0 0 1 1 1 0 Conserved region in Nab1 Phage_TAC_11 PF11836.8 CBZ35455.1 - 0.046 13.8 3.7 0.084 13.0 0.2 2.6 3 0 0 3 3 3 0 Phage tail tube protein, GTA-gp10 Sacchrp_dh_NADP PF03435.18 CBZ35457.1 - 6.9e-23 81.3 0.3 1.4e-22 80.3 0.3 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CBZ35457.1 - 0.00031 20.7 0.0 0.00073 19.5 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 CBZ35457.1 - 0.015 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CBZ35457.1 - 0.035 14.5 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CBZ35457.1 - 0.044 12.8 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TPR_16 PF13432.6 CBZ35458.1 - 4.8e-08 33.5 0.4 0.0012 19.4 0.6 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ35458.1 - 3e-06 26.9 3.2 1.5 9.1 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ35458.1 - 4e-06 26.4 1.7 0.5 10.3 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ35458.1 - 0.00063 20.0 1.5 0.22 11.8 0.6 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ35458.1 - 0.034 14.7 1.0 2.8 8.5 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat CheD PF03975.13 CBZ35458.1 - 0.071 13.2 0.1 0.53 10.4 0.1 2.2 2 0 0 2 2 2 0 CheD chemotactic sensory transduction zf-MYND PF01753.18 CBZ35458.1 - 1.4 9.1 15.7 4.5 7.5 15.7 2.0 1 1 0 1 1 1 0 MYND finger DUF2800 PF10926.8 CBZ35459.1 - 0.079 12.2 0.3 0.69 9.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2800) Pkinase PF00069.25 CBZ35460.1 - 3.3e-62 210.3 0.0 3.8e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35460.1 - 9.5e-40 136.5 0.0 1.2e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ35460.1 - 3.9e-06 26.4 0.0 5.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBZ35460.1 - 0.00011 21.3 0.1 0.00016 20.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CBZ35460.1 - 0.0038 16.9 0.2 0.49 10.0 0.0 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CBZ35460.1 - 0.0055 16.1 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBZ35460.1 - 0.0062 15.4 0.0 0.0084 14.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ35460.1 - 0.0072 16.3 1.8 0.037 14.0 1.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBZ35460.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 CBZ35460.1 - 0.042 13.4 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GP52 PF17468.2 CBZ35460.1 - 0.11 12.6 0.0 0.39 10.9 0.0 1.9 1 0 0 1 1 1 0 Phage gene product 52 AAA_23 PF13476.6 CBZ35461.1 - 7.4e-28 98.4 0.0 7.4e-28 98.4 0.0 7.2 3 2 1 5 5 3 1 AAA domain SMC_N PF02463.19 CBZ35461.1 - 1.3e-14 54.2 0.0 8.6e-07 28.6 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBZ35461.1 - 5.1e-08 33.1 0.0 0.0011 18.8 0.1 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CBZ35461.1 - 6.6e-08 32.7 14.2 8.8e-05 22.4 0.3 3.3 4 1 0 4 4 4 2 AAA ATPase domain SbcCD_C PF13558.6 CBZ35461.1 - 8.3e-08 32.4 0.0 2.9e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CBZ35461.1 - 0.0019 17.9 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad50_zn_hook PF04423.14 CBZ35461.1 - 0.0021 17.8 0.2 0.039 13.8 0.1 3.5 2 0 0 2 2 2 1 Rad50 zinc hook motif ABC_tran PF00005.27 CBZ35461.1 - 0.0031 18.0 0.0 0.0031 18.0 0.0 5.9 5 2 1 6 6 6 2 ABC transporter Pox_A_type_inc PF04508.12 CBZ35461.1 - 0.022 14.6 1.0 8.8 6.4 0.0 4.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Arf PF00025.21 CBZ35461.1 - 0.073 12.5 0.5 0.46 9.9 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CBZ35461.1 - 0.5 10.3 0.0 0.5 10.3 0.0 3.9 5 1 0 5 5 5 0 RsgA GTPase AAA_18 PF13238.6 CBZ35461.1 - 2 9.0 6.3 2.2 8.8 0.1 3.8 2 1 0 2 2 2 0 AAA domain DAGK_cat PF00781.24 CBZ35461.1 - 8.7 6.0 7.5 2.6 7.7 0.1 3.8 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain Ribosomal_S26e PF01283.19 CBZ35462.1 - 3.7e-35 120.6 3.4 3.9e-35 120.5 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Rad51 PF08423.11 CBZ35463.1 - 2.2e-128 426.9 0.2 3.7e-128 426.2 0.2 1.3 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.6 CBZ35463.1 - 1.1e-10 41.4 0.1 1.7e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CBZ35463.1 - 2e-10 40.6 0.1 3.3e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 CBZ35463.1 - 8.2e-05 23.1 0.1 0.00025 21.6 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 CBZ35463.1 - 9.2e-05 21.9 0.8 0.00038 19.9 0.8 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CBZ35463.1 - 0.0033 16.8 0.0 0.015 14.7 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 CBZ35463.1 - 0.042 14.1 0.1 0.12 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBZ35463.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 CBZ35463.1 - 0.74 8.9 0.0 0.74 8.9 0.0 2.0 3 0 0 3 3 3 0 PAXNEB protein Mod_r PF07200.13 CBZ35464.1 - 6.7e-13 49.0 5.9 1.2e-12 48.2 5.9 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein JMY PF15871.5 CBZ35464.1 - 0.00066 19.1 1.7 0.0011 18.4 1.7 1.3 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein TMCO5 PF14992.6 CBZ35464.1 - 0.0057 16.3 2.9 0.0077 15.8 2.9 1.2 1 0 0 1 1 1 1 TMCO5 family APG6_N PF17675.1 CBZ35464.1 - 0.0061 17.1 3.5 0.0061 17.1 3.5 2.1 2 0 0 2 2 2 1 Apg6 coiled-coil region ADIP PF11559.8 CBZ35464.1 - 0.0068 16.5 6.2 0.013 15.6 6.0 1.6 1 1 0 1 1 1 1 Afadin- and alpha -actinin-Binding End3 PF12761.7 CBZ35464.1 - 0.008 16.4 3.4 0.017 15.3 3.4 1.5 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 FlaC_arch PF05377.11 CBZ35464.1 - 0.012 15.9 4.6 0.19 12.2 1.9 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Adeno_52K PF03052.15 CBZ35464.1 - 0.017 14.6 0.9 0.028 13.8 0.9 1.3 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa Lectin_N PF03954.14 CBZ35464.1 - 0.019 14.7 1.7 0.06 13.1 1.7 1.8 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain COG2 PF06148.11 CBZ35464.1 - 0.02 15.0 1.5 0.05 13.7 1.5 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 GAS PF13851.6 CBZ35464.1 - 0.027 13.8 9.7 0.07 12.5 9.7 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 CBZ35464.1 - 0.027 14.8 8.1 0.027 14.8 8.1 2.1 2 0 0 2 2 1 0 Csm1 N-terminal domain Uso1_p115_C PF04871.13 CBZ35464.1 - 0.032 14.6 4.9 0.032 14.6 4.9 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1280 PF06918.14 CBZ35464.1 - 0.038 13.6 0.3 0.053 13.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) FAM184 PF15665.5 CBZ35464.1 - 0.043 13.6 6.6 0.017 14.9 4.0 1.7 2 0 0 2 2 1 0 Family with sequence similarity 184, A and B Spc24 PF08286.11 CBZ35464.1 - 0.045 14.0 3.7 0.098 12.9 2.2 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Cnn_1N PF07989.11 CBZ35464.1 - 0.06 13.5 5.0 0.055 13.6 2.7 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF4162 PF13732.6 CBZ35464.1 - 0.061 14.1 0.3 7.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) JAKMIP_CC3 PF16034.5 CBZ35464.1 - 0.067 13.1 9.9 0.028 14.4 6.4 1.9 1 1 1 2 2 2 0 JAKMIP CC3 domain DUF5082 PF16888.5 CBZ35464.1 - 0.085 13.1 3.4 0.23 11.7 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Phage_GP20 PF06810.11 CBZ35464.1 - 0.085 12.7 5.6 0.078 12.8 3.5 1.9 1 1 0 1 1 1 0 Phage minor structural protein GP20 Tup_N PF08581.10 CBZ35464.1 - 0.13 12.6 5.6 0.056 13.7 2.3 2.1 3 0 0 3 3 1 0 Tup N-terminal Urocanase_N PF17391.2 CBZ35464.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Urocanase N-terminal domain bZIP_1 PF00170.21 CBZ35464.1 - 0.15 12.2 1.9 0.5 10.5 1.9 2.0 1 0 0 1 1 1 0 bZIP transcription factor Fib_alpha PF08702.10 CBZ35464.1 - 0.17 12.1 9.1 1.2 9.4 5.5 2.9 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family 7TMR-HDED PF07697.11 CBZ35464.1 - 0.18 11.9 4.4 0.24 11.5 3.1 1.7 2 1 0 2 2 2 0 7TM-HD extracellular TSC22 PF01166.18 CBZ35464.1 - 0.2 12.0 4.8 0.75 10.2 4.4 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family ZapB PF06005.12 CBZ35464.1 - 0.2 12.1 8.3 0.49 10.9 8.3 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 CBZ35464.1 - 0.25 11.6 4.1 0.34 11.2 1.1 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 CBZ35464.1 - 0.26 11.8 9.8 1.2 9.6 6.1 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.8 CBZ35464.1 - 0.29 11.1 5.5 0.21 11.6 3.5 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-H PF05837.12 CBZ35464.1 - 0.31 11.5 6.9 0.43 11.0 6.1 1.7 1 1 0 1 1 1 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.5 CBZ35464.1 - 0.43 10.7 10.0 1.4 9.0 10.0 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation Tropomyosin_1 PF12718.7 CBZ35464.1 - 0.46 10.6 7.9 0.061 13.5 3.2 1.9 2 0 0 2 2 2 0 Tropomyosin like PI3K_P85_iSH2 PF16454.5 CBZ35464.1 - 0.69 9.5 8.1 0.34 10.5 4.8 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain YscO PF07321.12 CBZ35464.1 - 0.71 9.8 11.2 0.11 12.5 5.7 2.1 2 0 0 2 2 2 0 Type III secretion protein YscO DivIC PF04977.15 CBZ35464.1 - 0.93 9.3 8.8 0.11 12.3 2.5 2.5 1 1 1 2 2 2 0 Septum formation initiator OmpH PF03938.14 CBZ35464.1 - 1.2 9.5 8.1 7.2 6.9 8.2 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) FliD_N PF02465.18 CBZ35464.1 - 2.3 9.0 5.7 4.9 7.9 0.6 2.7 3 0 0 3 3 2 0 Flagellar hook-associated protein 2 N-terminus DUF16 PF01519.16 CBZ35464.1 - 2.7 8.5 7.5 6.2 7.4 5.7 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF1664 PF07889.12 CBZ35464.1 - 7.1 6.7 7.0 4.1 7.5 2.9 2.2 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) Peptidase_M8 PF01457.16 CBZ35465.1 - 1.4e-141 472.8 0.7 1.8e-141 472.5 0.7 1.0 1 0 0 1 1 1 1 Leishmanolysin Pkinase PF00069.25 CBZ35466.1 - 1.3e-54 185.3 0.0 6.8e-37 127.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35466.1 - 6.3e-22 78.1 0.0 9.4e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ35466.1 - 0.0077 16.2 2.3 0.046 13.6 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ35466.1 - 0.021 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ35466.1 - 0.16 10.9 0.0 0.38 9.6 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 CBZ35467.1 - 1.3e-54 185.3 0.0 6.8e-37 127.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35467.1 - 6.3e-22 78.1 0.0 9.4e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ35467.1 - 0.0077 16.2 2.3 0.046 13.6 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ35467.1 - 0.021 14.2 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ35467.1 - 0.16 10.9 0.0 0.38 9.6 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain DUF812 PF05667.11 CBZ35468.1 - 0.0058 15.6 0.7 0.0078 15.2 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Med9 PF07544.13 CBZ35468.1 - 0.0067 16.5 1.8 3.3 7.9 1.3 2.8 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.12 CBZ35468.1 - 0.024 15.2 10.1 1.4 9.6 4.4 3.3 3 0 0 3 3 3 0 SlyX DUF4618 PF15397.6 CBZ35468.1 - 0.047 13.1 2.1 0.26 10.7 0.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) APG6_N PF17675.1 CBZ35468.1 - 0.057 14.0 2.4 0.1 13.1 0.2 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region USP8_interact PF08941.10 CBZ35468.1 - 0.077 12.8 0.5 0.5 10.2 0.4 2.1 2 0 0 2 2 2 0 USP8 interacting BLOC1_2 PF10046.9 CBZ35468.1 - 0.089 13.1 0.5 9.8 6.6 0.0 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 CBZ35468.1 - 0.098 12.5 1.4 0.27 11.0 1.1 1.7 1 1 0 1 1 1 0 Spindle Pole Component 29 DUF3450 PF11932.8 CBZ35468.1 - 0.27 10.5 5.1 0.29 10.4 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 CBZ35468.1 - 0.4 10.7 8.7 2 8.5 3.3 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein CREPT PF16566.5 CBZ35468.1 - 0.72 10.0 4.6 12 6.1 0.1 2.5 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ZapB PF06005.12 CBZ35468.1 - 0.93 10.0 9.3 3.2 8.2 2.5 3.3 3 0 0 3 3 3 0 Cell division protein ZapB Csm1_N PF18504.1 CBZ35468.1 - 3.2 8.2 5.2 33 4.9 0.1 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain Hemerythrin PF01814.23 CBZ35468.1 - 4.9 7.8 8.7 6.1 7.5 2.1 3.2 3 1 1 4 4 4 0 Hemerythrin HHE cation binding domain AAA_6 PF12774.7 CBZ35470.1 - 3.5e-151 502.8 0.0 6.2e-149 495.4 0.0 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ35470.1 - 3.1e-117 392.1 1.7 3.1e-117 392.1 1.7 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CBZ35470.1 - 1.9e-106 355.7 0.1 1e-105 353.3 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBZ35470.1 - 2.9e-93 311.9 0.0 3e-90 302.1 0.0 3.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CBZ35470.1 - 2e-79 265.8 2.3 2e-79 265.8 2.3 2.6 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ35470.1 - 4.5e-64 215.3 0.0 6e-59 198.6 0.0 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ35470.1 - 4e-54 182.8 0.0 1.1e-53 181.4 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 CBZ35470.1 - 1.4e-46 159.1 3.7 1.4e-46 159.1 3.7 2.0 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 CBZ35470.1 - 8e-46 155.0 0.5 6.6e-44 148.8 0.1 3.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 CBZ35470.1 - 1.4e-16 60.5 0.1 4.5e-16 58.9 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 CBZ35470.1 - 4e-16 59.3 0.0 2.3e-15 56.8 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBZ35470.1 - 2.1e-15 56.9 0.1 0.00027 20.9 0.0 6.5 5 2 0 5 5 5 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ35470.1 - 9.8e-08 32.4 1.3 1.1 9.6 0.0 5.3 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 CBZ35470.1 - 1.5e-06 28.5 0.0 0.026 14.9 0.0 4.3 4 0 0 4 4 4 2 RNA helicase AAA_16 PF13191.6 CBZ35470.1 - 4.1e-06 27.3 0.6 0.46 10.9 0.0 5.8 5 1 1 6 6 5 2 AAA ATPase domain AAA PF00004.29 CBZ35470.1 - 4.3e-05 23.9 0.4 1.3 9.4 0.0 5.1 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CBZ35470.1 - 0.00035 21.1 0.0 0.24 12.0 0.0 4.0 3 0 0 3 3 2 1 AAA domain Baculo_PEP_C PF04513.12 CBZ35470.1 - 0.0023 18.0 4.0 3.8 7.5 0.1 5.1 5 0 0 5 5 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_24 PF13479.6 CBZ35470.1 - 0.0038 17.0 0.4 1.8 8.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 CBZ35470.1 - 0.004 16.2 3.6 0.22 10.6 0.0 4.3 6 0 0 6 6 6 1 Type II/IV secretion system protein PhoH PF02562.16 CBZ35470.1 - 0.15 11.5 3.4 3.4 7.1 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein Mg_chelatase PF01078.21 CBZ35470.1 - 0.15 11.4 5.2 0.93 8.8 0.0 4.1 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CBZ35470.1 - 0.16 11.6 15.9 2.9 7.6 0.1 4.4 5 0 0 5 5 4 0 AAA domain SRP54 PF00448.22 CBZ35470.1 - 1.1 8.9 4.0 11 5.6 0.1 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 CBZ35470.1 - 1.4 8.4 5.1 13 5.3 0.0 4.2 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 CBZ35470.1 - 2.7 8.3 4.8 66 3.8 0.1 4.1 5 0 0 5 5 4 0 AAA domain AAA_33 PF13671.6 CBZ35470.1 - 6.4 6.9 8.0 30 4.8 0.0 4.4 4 0 0 4 4 3 0 AAA domain Pkinase PF00069.25 CBZ35471.1 - 1.4e-51 175.4 0.0 2.2e-51 174.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35471.1 - 1.3e-36 126.2 0.0 2.2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase BAF1_ABF1 PF04684.13 CBZ35471.1 - 0.48 9.4 1.5 0.77 8.7 1.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ER_lumen_recept PF00810.18 CBZ35472.1 - 5.4e-50 170.0 8.6 5.4e-50 170.0 8.6 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor ATP_synt_H PF05493.13 CBZ35473.1 - 7.9e-19 67.9 6.7 8.7e-19 67.8 6.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit H MgtE PF01769.16 CBZ35473.1 - 0.34 11.3 4.8 0.37 11.2 4.8 1.0 1 0 0 1 1 1 0 Divalent cation transporter WD40 PF00400.32 CBZ35474.1 - 2.8e-13 50.1 6.9 0.00056 20.7 0.1 6.7 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ35474.1 - 6e-12 45.7 0.2 0.0011 19.2 0.0 3.6 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ35474.1 - 0.061 12.3 0.4 0.27 10.2 0.2 2.3 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_3 PF15911.5 CBZ35474.1 - 0.093 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat TerC PF03741.16 CBZ35475.1 - 0.032 13.9 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein TerC family Ank_4 PF13637.6 CBZ35477.1 - 1.2e-18 67.2 0.3 2.9e-09 37.3 0.1 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ35477.1 - 8.7e-18 64.7 2.8 8.6e-12 45.5 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBZ35477.1 - 1.3e-16 60.4 3.4 2.8e-07 30.7 0.4 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ35477.1 - 3.3e-11 42.4 1.1 0.00093 19.5 0.1 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CBZ35477.1 - 3.8e-06 27.1 1.9 0.0096 16.3 0.2 3.3 3 1 1 4 4 4 2 Ankyrin repeat Metallophos PF00149.28 CBZ35478.1 - 4.9e-37 128.4 0.1 6.4e-37 128.0 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ35478.1 - 2.3e-17 63.1 1.1 4.3e-17 62.3 1.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain BTB_2 PF02214.22 CBZ35479.1 - 1e-11 45.0 0.0 1.7e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4539 PF15072.6 CBZ35480.1 - 1.7e-13 50.4 0.0 2.7e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) SNARE_assoc PF09335.11 CBZ35481.1 - 2e-09 38.0 4.0 2.2e-09 37.8 1.0 2.6 2 0 0 2 2 2 1 SNARE associated Golgi protein EF-hand_5 PF13202.6 CBZ35481.1 - 0.00014 21.2 0.0 0.00048 19.5 0.0 1.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBZ35481.1 - 0.0017 18.1 0.0 0.0085 15.9 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 CBZ35481.1 - 0.0057 16.1 0.0 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CBZ35481.1 - 0.071 13.6 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Sas10_Utp3 PF04000.15 CBZ35482.1 - 8.1e-18 64.8 1.2 2.5e-17 63.3 1.2 1.9 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Sas10 PF09368.10 CBZ35482.1 - 1.6e-15 57.3 4.4 1.6e-15 57.3 4.4 1.9 2 0 0 2 2 2 1 Sas10 C-terminal domain Stm1_N PF09598.10 CBZ35482.1 - 4.4 8.2 8.4 1.5 9.8 3.9 2.6 2 0 0 2 2 2 0 Stm1 SNF2_N PF00176.23 CBZ35486.1 - 5.5e-52 176.6 0.0 1.2e-50 172.3 0.0 2.1 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ35486.1 - 2.1e-16 60.2 0.3 5.6e-16 58.9 0.1 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 CBZ35486.1 - 1.8e-07 31.0 3.0 3.6e-07 30.1 1.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger ResIII PF04851.15 CBZ35486.1 - 3.4e-07 30.4 0.4 1.6e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CBZ35486.1 - 5.3e-07 29.4 4.9 1.2e-06 28.3 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBZ35486.1 - 3.9e-06 26.6 4.5 8.2e-06 25.6 4.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ35486.1 - 4.4e-05 23.7 5.5 4.4e-05 23.7 5.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CBZ35486.1 - 0.00023 21.1 9.8 0.00057 19.8 9.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBZ35486.1 - 0.00057 20.0 4.5 0.0012 19.0 4.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING ERCC3_RAD25_C PF16203.5 CBZ35486.1 - 0.00064 19.0 0.2 0.0016 17.7 0.2 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_2 PF13923.6 CBZ35486.1 - 0.0011 18.7 9.6 0.0064 16.3 9.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CBZ35486.1 - 0.0022 17.8 0.0 0.0045 16.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-4CXXC_R1 PF10497.9 CBZ35486.1 - 0.0035 17.5 5.9 0.0094 16.2 5.9 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Prok-RING_4 PF14447.6 CBZ35486.1 - 0.0036 17.1 4.5 0.01 15.7 4.5 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CBZ35486.1 - 0.66 10.3 7.8 0.18 12.1 3.8 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger domain VP_N-CPKC PF11475.8 CBZ35486.1 - 1.6 8.7 4.5 0.34 10.8 0.4 2.1 2 0 0 2 2 2 0 Virion protein N terminal domain RPE65 PF03055.15 CBZ35487.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Retinal pigment epithelial membrane protein PAP_assoc PF03828.19 CBZ35489.1 - 8.1e-13 48.4 0.0 1.7e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase DSPc PF00782.20 CBZ35490.1 - 3.6e-18 65.6 0.0 1.3e-16 60.6 0.0 2.6 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain EF-hand_7 PF13499.6 CBZ35491.1 - 2.5e-14 53.5 0.1 1.3e-06 28.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CBZ35491.1 - 3.7e-13 49.6 0.0 1.2e-10 41.6 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CBZ35491.1 - 3.7e-12 44.9 0.2 4.9e-05 22.6 0.0 4.1 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBZ35491.1 - 3.3e-11 42.2 0.9 1.5e-05 24.6 0.0 3.5 3 1 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CBZ35491.1 - 8.8e-09 35.1 0.5 5.5e-05 22.9 0.0 4.0 1 1 3 4 4 4 3 EF-hand domain pair EFhand_Ca_insen PF08726.10 CBZ35491.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.6 1 1 0 1 1 1 0 Ca2+ insensitive EF hand Adenine_glyco PF03352.13 CBZ35491.1 - 0.13 12.0 0.0 3.1 7.5 0.0 2.1 1 1 1 2 2 2 0 Methyladenine glycosylase RNA_pol_Rpb8 PF03870.15 CBZ35492.1 - 4.1e-36 124.2 0.0 4.6e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CBZ35492.1 - 0.00058 19.9 0.3 0.56 10.3 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G Myco_19_kDa PF05481.12 CBZ35492.1 - 0.068 13.4 0.1 0.092 13.0 0.1 1.2 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen PP_kinase_C PF13090.6 CBZ35493.1 - 0.18 11.2 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 2 LPD23 PF18838.1 CBZ35493.1 - 0.28 11.0 1.4 1.1 9.0 0.1 2.8 2 1 0 2 2 2 0 Large polyvalent protein associated domain 23 CSD PF00313.22 CBZ35495.1 - 2.5e-15 56.0 0.2 3.3e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain DUF5318 PF17249.2 CBZ35496.1 - 0.0033 17.2 2.2 0.2 11.4 0.3 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5318) Phage_tail_APC PF16778.5 CBZ35497.1 - 0.13 12.2 0.1 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Phage tail assembly chaperone protein OrfB_IS605 PF01385.19 CBZ35497.1 - 0.18 12.0 0.9 0.29 11.4 0.1 1.7 1 1 1 2 2 2 0 Probable transposase MCM PF00493.23 CBZ35499.1 - 2.4e-93 311.4 0.0 4.2e-93 310.5 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ35499.1 - 5.1e-36 123.3 0.1 8.9e-36 122.5 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ35499.1 - 9.2e-27 93.3 0.1 2.1e-26 92.1 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBZ35499.1 - 9.2e-10 39.0 3.4 1.5e-09 38.4 0.9 2.5 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBZ35499.1 - 1.2e-07 31.3 0.0 1.3e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM2_N PF12619.8 CBZ35499.1 - 6.1e-06 26.6 24.6 6.1e-06 26.6 24.6 3.5 5 0 0 5 5 4 1 Mini-chromosome maintenance protein 2 AAA_5 PF07728.14 CBZ35499.1 - 1.8e-05 24.7 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CBZ35499.1 - 0.0017 18.2 0.0 0.0082 16.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CBZ35499.1 - 0.0052 16.6 0.1 0.021 14.7 0.1 2.0 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 CBZ35499.1 - 0.036 14.5 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBZ35499.1 - 0.12 12.1 0.0 0.5 10.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain CagY_M PF07337.11 CBZ35499.1 - 1.8 8.2 6.7 0.29 10.8 1.4 2.4 3 0 0 3 3 3 0 DC-EC Repeat M16C_assoc PF08367.11 CBZ35499.1 - 2 7.5 3.5 0.75 8.9 0.0 1.9 2 0 0 2 2 2 0 Peptidase M16C associated Ribonuc_red_lgC PF02867.15 CBZ35503.1 - 2.7e-182 607.0 0.0 3.3e-182 606.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CBZ35503.1 - 1.7e-23 82.4 0.0 4.4e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CBZ35503.1 - 3.9e-11 43.4 0.0 9.4e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain Lebercilin PF15619.6 CBZ35504.1 - 0.0023 17.6 31.6 0.33 10.6 28.5 3.2 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease HGD-D PF06050.13 CBZ35504.1 - 0.37 10.5 4.0 0.53 10.0 4.0 1.4 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component TssC PF17541.2 CBZ35504.1 - 0.38 9.5 6.3 0.5 9.1 6.3 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB Spc7 PF08317.11 CBZ35504.1 - 0.67 8.8 25.2 3.6 6.4 11.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 CBZ35504.1 - 0.74 9.9 8.8 1.1 9.3 2.9 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bep_C_terminal PF17841.1 CBZ35504.1 - 0.81 9.9 6.1 5.4 7.3 1.7 2.5 1 1 1 2 2 2 0 BID domain of Bartonella effector protein (Bep) T5orf172 PF10544.9 CBZ35504.1 - 1.7 9.2 6.3 0.39 11.3 1.2 2.3 1 1 1 2 2 2 0 T5orf172 domain CarD_CdnL_TRCF PF02559.16 CBZ35504.1 - 2.3 9.0 4.6 3.4 8.4 0.6 2.5 1 1 1 2 2 2 0 CarD-like/TRCF domain Fib_alpha PF08702.10 CBZ35504.1 - 4.1 7.6 11.6 15 5.8 10.2 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Exo_endo_phos PF03372.23 CBZ35505.1 - 4.1e-08 33.0 0.0 0.0074 15.8 0.0 3.6 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Pertus-S4-tox PF09275.10 CBZ35505.1 - 0.85 9.9 3.6 16 5.9 0.1 3.6 4 0 0 4 4 4 0 Pertussis toxin S4 subunit HEAT_2 PF13646.6 CBZ35507.1 - 0.085 13.3 2.9 5.1 7.5 0.0 3.2 3 0 0 3 3 3 0 HEAT repeats ATP-synt_I PF03899.15 CBZ35507.1 - 0.14 12.5 0.8 0.55 10.6 0.1 2.2 2 0 0 2 2 2 0 ATP synthase I chain DUF4381 PF14316.6 CBZ35507.1 - 0.64 10.2 5.3 0.23 11.7 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) adh_short PF00106.25 CBZ35508.1 - 9e-16 57.9 0.0 7.7e-09 35.3 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ35508.1 - 1e-12 48.1 0.0 2.1e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Tctex-1 PF03645.13 CBZ35509.1 - 9.2e-25 86.9 0.1 1.1e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family Ribosomal_S11 PF00411.19 CBZ35510.1 - 4.5e-47 159.0 1.7 5.6e-47 158.7 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 LSM PF01423.22 CBZ35511.1 - 0.0018 18.0 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ35511.1 - 0.046 13.9 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain MtN3_slv PF03083.16 CBZ35512.1 - 0.11 12.6 0.3 0.18 11.8 0.3 1.3 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Serinc PF03348.15 CBZ35513.1 - 7.9e-55 186.5 34.4 6.4e-54 183.5 34.4 1.9 1 1 0 1 1 1 1 Serine incorporator (Serinc) DUF3899 PF13038.6 CBZ35513.1 - 8.1 7.0 15.0 2.6 8.6 6.4 4.2 3 2 0 3 3 3 0 Domain of unknown function (DUF3899) PPR_2 PF13041.6 CBZ35515.1 - 0.00032 20.8 0.3 2.6 8.3 0.1 5.1 5 1 1 6 6 6 1 PPR repeat family PPR PF01535.20 CBZ35515.1 - 0.00035 20.6 2.0 0.19 12.1 0.1 4.9 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.6 CBZ35515.1 - 0.029 14.4 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Ribosomal_S10 PF00338.22 CBZ35516.1 - 5.6e-24 84.2 0.3 6.5e-24 84.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 CBZ35516.1 - 0.15 12.9 0.0 0.3 11.9 0.0 1.5 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Ribosomal_S10 PF00338.22 CBZ35517.1 - 5.6e-24 84.2 0.3 6.5e-24 84.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e PriA_C PF18074.1 CBZ35517.1 - 0.15 12.9 0.0 0.3 11.9 0.0 1.5 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Hormone_5 PF00184.17 CBZ35520.1 - 0.12 13.2 0.5 0.3 12.0 0.5 1.6 1 0 0 1 1 1 0 Neurohypophysial hormones, C-terminal Domain HMG_box_2 PF09011.10 CBZ35522.1 - 0.00061 20.3 2.7 0.5 11.0 0.1 2.8 2 0 0 2 2 2 2 HMG-box domain Herpes_pp85 PF04637.12 CBZ35522.1 - 0.032 12.7 1.3 0.063 11.7 1.3 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) HMG_box PF00505.19 CBZ35522.1 - 0.039 14.4 1.5 14 6.2 0.1 2.8 2 0 0 2 2 2 0 HMG (high mobility group) box HGTP_anticodon2 PF12745.7 CBZ35522.1 - 0.11 11.9 1.4 0.23 10.9 1.4 1.4 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs ATP-grasp_4 PF13535.6 CBZ35523.1 - 5.6e-10 39.0 0.0 7.3e-08 32.2 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CBZ35523.1 - 2.1e-06 27.9 0.0 6.2e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CBZ35523.1 - 9.1e-05 22.0 0.1 0.0022 17.5 0.1 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 CBZ35523.1 - 0.00048 19.9 0.3 0.0012 18.6 0.3 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.6 CBZ35523.1 - 0.00077 19.2 0.0 1.7 8.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon DUF4763 PF15960.5 CBZ35523.1 - 0.02 14.2 1.0 0.053 12.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) RimK PF08443.11 CBZ35523.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Spc7 PF08317.11 CBZ35523.1 - 0.54 9.1 4.5 0.86 8.4 4.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ubiquitin PF00240.23 CBZ35525.1 - 6.4e-05 22.6 0.1 0.00013 21.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family SP2 PF03014.14 CBZ35525.1 - 0.16 10.4 1.4 0.25 9.7 1.4 1.2 1 0 0 1 1 1 0 Structural protein 2 WD40 PF00400.32 CBZ35526.1 - 1.9e-34 117.1 29.3 8.8e-05 23.2 0.1 10.6 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ35526.1 - 5.2e-15 55.5 0.4 0.0091 16.3 0.0 6.3 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBZ35526.1 - 1.9e-05 24.7 0.0 1 9.2 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBZ35526.1 - 7.8e-05 22.1 0.8 0.025 13.9 0.9 3.1 2 1 1 3 3 3 2 WD40-like domain Gmad1 PF10647.9 CBZ35526.1 - 0.031 14.0 0.1 7.9 6.1 0.1 3.0 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain WD40_3 PF15911.5 CBZ35526.1 - 0.068 13.2 1.5 2.2 8.4 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat PQQ_3 PF13570.6 CBZ35526.1 - 0.096 13.2 11.9 82 3.9 0.0 6.9 6 1 0 6 6 6 0 PQQ-like domain Amastin PF07344.11 CBZ35527.1 - 0.0024 17.7 12.3 0.0037 17.1 12.3 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CBZ35527.1 - 0.041 13.8 9.1 0.069 13.0 9.1 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF3810 PF12725.7 CBZ35527.1 - 2.2 7.5 7.8 0.93 8.8 4.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Amastin PF07344.11 CBZ35528.1 - 3.4e-31 108.2 22.5 2.2e-18 66.6 3.9 2.5 2 1 0 2 2 2 2 Amastin surface glycoprotein DUF5134 PF17197.4 CBZ35528.1 - 1.1 9.2 10.0 0.51 10.2 0.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5134) ETF_alpha PF00766.19 CBZ35529.1 - 1.6e-35 120.9 0.2 1.6e-35 120.9 0.2 2.0 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 CBZ35529.1 - 3.9e-28 98.6 7.0 6e-28 98.0 7.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AMP-binding PF00501.28 CBZ35530.1 - 8e-54 182.8 0.0 1.5e-49 168.8 0.0 3.0 3 0 0 3 3 3 3 AMP-binding enzyme AMP-binding_C PF13193.6 CBZ35530.1 - 3.2e-10 40.8 0.6 7.6e-10 39.6 0.6 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP-synt_C PF00137.21 CBZ35531.1 - 5e-25 87.6 49.1 3e-18 65.9 13.6 3.1 3 0 0 3 3 3 2 ATP synthase subunit C LRR_6 PF13516.6 CBZ35532.1 - 5.5e-07 29.1 6.2 0.44 10.7 0.0 4.8 4 0 0 4 4 4 3 Leucine Rich repeat zf-AN1 PF01428.16 CBZ35533.1 - 7e-09 35.7 9.1 1.1e-08 35.1 9.1 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CBZ35533.1 - 0.00067 20.0 3.3 0.001 19.4 3.3 1.3 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain Copine PF07002.16 CBZ35535.1 - 1.3e-64 217.6 0.0 1.8e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 CBZ35535.1 - 7.2e-28 96.9 0.0 7.6e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 CBZ35535.1 - 0.00031 20.9 0.0 0.00058 20.0 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 CBZ35535.1 - 0.0094 16.2 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain HSP70 PF00012.20 CBZ35536.1 - 3.2e-250 831.5 14.1 3.6e-250 831.3 14.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ35536.1 - 7.8e-21 74.2 0.8 3.1e-18 65.7 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CBZ35536.1 - 0.0015 18.3 0.0 0.0055 16.5 0.0 2.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 CBZ35536.1 - 0.0018 17.6 0.7 0.039 13.2 0.1 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DUF1542 PF07564.11 CBZ35536.1 - 1.1 9.4 9.9 0.086 13.0 1.6 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) WWE PF02825.20 CBZ35538.1 - 0.0019 18.7 0.0 0.0041 17.7 0.0 1.6 1 0 0 1 1 1 1 WWE domain SGL PF08450.12 CBZ35539.1 - 2.3e-39 135.4 0.0 8.3e-39 133.6 0.0 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region FAD_binding_1 PF00667.20 CBZ35540.1 - 5e-40 137.4 0.0 7.6e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CBZ35540.1 - 5.5e-34 117.4 0.4 3.5e-33 114.8 0.2 2.2 2 1 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CBZ35540.1 - 2.6e-13 50.6 0.0 1.7e-12 48.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF5614 PF18474.1 CBZ35540.1 - 0.098 12.0 0.1 0.19 11.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5614) DHDPS PF00701.22 CBZ35540.1 - 0.15 10.7 0.0 0.33 9.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family BILBO1_N PF18281.1 CBZ35541.1 - 2.5e-29 101.6 0.2 6.5e-29 100.2 0.2 1.8 1 0 0 1 1 1 1 BILBO1 N-terminal domain Exonuc_VII_L PF02601.15 CBZ35541.1 - 0.005 16.4 0.9 0.0071 16.0 0.9 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit Filament PF00038.21 CBZ35541.1 - 0.12 11.9 14.5 0.19 11.3 14.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein DnaJ PF00226.31 CBZ35543.1 - 5.2e-17 61.7 1.0 1.1e-16 60.7 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain PDZ_6 PF17820.1 CBZ35543.1 - 0.024 14.5 0.0 0.29 11.0 0.0 2.6 3 0 0 3 3 3 0 PDZ domain Biopterin_H PF00351.21 CBZ35544.1 - 3.1e-131 437.4 0.0 4e-131 437.0 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase LCE6A PF15858.5 CBZ35545.1 - 1.2 9.9 7.5 3.9 8.3 1.3 2.5 2 0 0 2 2 2 0 Late cornified envelope protein 6A family zf-C3HC4_2 PF13923.6 CBZ35546.1 - 7.2e-06 25.7 11.0 1.2e-05 25.0 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ35546.1 - 1.4e-05 25.0 11.6 2.7e-05 24.1 11.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ35546.1 - 6.3e-05 22.8 9.2 0.00011 22.0 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CBZ35546.1 - 9.5e-05 22.2 7.4 0.00016 21.5 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ35546.1 - 0.00022 21.1 7.1 0.00036 20.4 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CBZ35546.1 - 0.0011 19.2 10.2 0.0019 18.5 10.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CBZ35546.1 - 0.0021 18.2 13.8 0.0033 17.6 13.8 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CBZ35546.1 - 0.0082 16.0 8.3 0.015 15.2 8.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C2H2_3 PF13878.6 CBZ35546.1 - 0.043 13.7 1.4 0.42 10.5 0.3 2.5 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-HIT PF04438.16 CBZ35546.1 - 0.16 11.9 4.5 0.15 12.0 1.2 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-RING_6 PF14835.6 CBZ35546.1 - 0.25 11.3 5.7 0.57 10.1 5.7 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Spc7 PF08317.11 CBZ35546.1 - 0.26 10.1 10.9 0.16 10.8 9.0 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein FapA PF03961.13 CBZ35546.1 - 0.34 9.5 4.2 0.3 9.6 2.6 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A zf-RING_10 PF16685.5 CBZ35546.1 - 0.36 11.0 4.4 0.67 10.1 4.4 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Pup PF05639.11 CBZ35546.1 - 0.6 11.1 4.5 5.5 8.0 0.2 2.9 2 1 0 2 2 2 0 Pup-like protein CENP-F_leu_zip PF10473.9 CBZ35546.1 - 2.6 8.1 16.9 79 3.3 13.7 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RecR PF02132.15 CBZ35546.1 - 2.8 7.6 4.5 4.7 6.9 1.1 2.6 1 1 1 2 2 2 0 RecR protein BST2 PF16716.5 CBZ35546.1 - 7 7.3 13.5 2.4 8.8 8.0 2.8 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 DUF1664 PF07889.12 CBZ35546.1 - 8.4 6.5 9.9 7.6 6.6 2.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DEAD PF00270.29 CBZ35547.1 - 2.1e-41 141.6 0.0 4.4e-41 140.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ35547.1 - 2.8e-25 88.8 0.0 1.3e-24 86.7 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBZ35547.1 - 9.7e-12 44.9 0.1 2.3e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBZ35547.1 - 5.9e-08 32.9 0.0 2.5e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2753 PF10952.8 CBZ35547.1 - 0.018 15.2 0.1 0.037 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) DUF3160 PF11369.8 CBZ35547.1 - 0.053 12.0 0.1 0.1 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) HGD-D PF06050.13 CBZ35547.1 - 0.12 12.1 0.2 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DUF2500 PF10694.9 CBZ35547.1 - 0.19 12.2 0.4 0.45 11.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) UbiA PF01040.18 CBZ35548.1 - 2.5e-37 128.6 17.6 2.8e-37 128.4 16.9 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family TP2 PF01254.18 CBZ35549.1 - 0.64 10.6 3.4 1.1 9.8 3.4 1.5 1 0 0 1 1 1 0 Nuclear transition protein 2 Hydrolase_3 PF08282.12 CBZ35550.1 - 4.6e-21 75.7 0.0 6.3e-20 72.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ35550.1 - 1.9e-05 24.3 0.0 3.1e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 CBZ35551.1 - 1.1e-36 126.9 0.2 3e-35 122.2 0.2 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ35551.1 - 1.5e-09 37.8 0.0 9.1e-06 25.4 0.0 2.3 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CBZ35551.1 - 0.0052 17.1 3.5 0.13 12.5 3.5 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBZ35552.1 - 3.8e-52 177.6 0.0 5.2e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ35552.1 - 2e-14 53.7 0.0 3.1e-07 30.2 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CBZ35552.1 - 2.3e-09 37.9 0.8 0.00022 21.6 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ35552.1 - 0.00017 22.1 1.4 0.035 14.5 0.0 3.0 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CBZ35552.1 - 0.005 16.9 0.0 0.018 15.1 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBZ35552.1 - 0.016 15.3 0.1 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBZ35553.1 - 5.9e-51 173.7 0.0 7.1e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ35553.1 - 2.9e-18 66.3 0.0 5.5e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CBZ35553.1 - 1.8e-07 31.7 0.1 0.028 14.7 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ35553.1 - 0.0047 17.4 1.4 2.1 8.7 0.0 3.5 1 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CBZ35553.1 - 0.019 15.1 0.0 0.07 13.2 0.0 2.0 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBZ35553.1 - 0.058 13.5 0.0 0.58 10.2 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBZ35554.1 - 5.9e-50 170.4 0.0 2e-33 116.2 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ35554.1 - 3.1e-15 56.4 0.0 6.8e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CBZ35554.1 - 2e-08 34.8 0.0 0.0036 17.6 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ35554.1 - 0.0021 18.5 0.1 1 9.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBZ35554.1 - 0.014 15.5 0.0 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CBZ35554.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Amastin PF07344.11 CBZ35555.1 - 3e-50 170.1 7.1 3.9e-50 169.7 7.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ35556.1 - 6.4e-34 117.0 6.9 9.5e-34 116.5 6.9 1.2 1 0 0 1 1 1 1 Amastin surface glycoprotein ECSCR PF15820.5 CBZ35556.1 - 1.4 8.8 5.1 3.7 7.4 0.2 2.5 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator zf-CCCH_4 PF18044.1 CBZ35557.1 - 1e-05 25.2 6.4 1.6e-05 24.5 6.4 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ35557.1 - 0.00025 21.0 6.7 0.00042 20.3 6.7 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CBZ35557.1 - 0.00039 21.1 0.4 0.00078 20.1 0.4 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 CBZ35557.1 - 0.0004 20.2 4.7 0.00072 19.4 4.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CBZ35557.1 - 0.0055 17.1 7.4 0.011 16.1 7.4 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger IMS PF00817.20 CBZ35558.1 - 1.4e-35 122.6 0.1 3.8e-35 121.1 0.1 1.8 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CBZ35558.1 - 2.1e-12 47.8 0.4 8e-12 45.9 0.4 2.0 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CBZ35558.1 - 0.00027 21.1 0.0 0.00065 19.9 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif SPX PF03105.19 CBZ35558.1 - 0.0014 18.7 3.3 0.0014 18.7 3.3 2.1 2 0 0 2 2 2 1 SPX domain ATP-grasp_5 PF13549.6 CBZ35558.1 - 0.16 11.4 0.2 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain IMS PF00817.20 CBZ35559.1 - 3.1e-39 134.3 0.0 5.3e-39 133.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CBZ35559.1 - 2.7e-12 47.4 0.8 4.9e-12 46.6 0.1 1.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CBZ35559.1 - 0.00047 20.3 0.0 0.0014 18.9 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif IMS PF00817.20 CBZ35560.1 - 1.8e-06 28.0 0.0 1.8e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 impB/mucB/samB family IMS PF00817.20 CBZ35561.1 - 0.07 13.1 0.4 1.1 9.2 0.4 2.7 1 1 0 1 1 1 0 impB/mucB/samB family AAA PF00004.29 CBZ35563.1 - 4.6e-30 104.7 0.0 1.9e-21 76.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ35563.1 - 6.2e-08 33.2 3.6 7.6e-08 32.9 0.4 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CBZ35563.1 - 4e-06 26.9 0.0 8.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ35563.1 - 8.6e-06 26.1 0.0 5.3e-05 23.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBZ35563.1 - 2.3e-05 24.4 0.0 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CBZ35563.1 - 3.1e-05 23.8 0.0 6.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBZ35563.1 - 7.9e-05 22.8 0.0 0.00021 21.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBZ35563.1 - 0.00021 21.0 0.0 0.00046 20.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBZ35563.1 - 0.0019 17.6 0.1 0.0035 16.8 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CBZ35563.1 - 0.0022 17.3 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 CBZ35563.1 - 0.0076 16.6 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.12 CBZ35563.1 - 0.0077 16.2 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_2 PF07724.14 CBZ35563.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 CBZ35563.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CBZ35563.1 - 0.017 14.7 0.1 0.11 12.1 0.1 2.2 1 1 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 CBZ35563.1 - 0.019 15.3 0.5 0.6 10.4 0.0 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF815 PF05673.13 CBZ35563.1 - 0.02 14.0 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CBZ35563.1 - 0.027 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 CBZ35563.1 - 0.036 13.9 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBZ35563.1 - 0.038 14.6 0.0 0.075 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CBZ35563.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 CBZ35563.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 CBZ35563.1 - 0.06 13.6 0.0 0.32 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CBZ35563.1 - 0.061 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 CBZ35563.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CBZ35563.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 CBZ35563.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Cytidylate_kin2 PF13189.6 CBZ35563.1 - 0.093 12.8 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family Syntaxin PF00804.25 CBZ35564.1 - 1.7e-10 40.9 4.4 1.9e-10 40.8 4.4 1.0 1 0 0 1 1 1 1 Syntaxin PTRF_SDPR PF15237.6 CBZ35564.1 - 0.027 14.1 1.9 0.026 14.1 1.9 1.0 1 0 0 1 1 1 0 PTRF/SDPR family Syntaxin PF00804.25 CBZ35565.1 - 6.1e-25 88.1 11.3 6.1e-25 88.1 11.3 1.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CBZ35565.1 - 7.2e-14 51.5 0.7 2.6e-13 49.8 0.7 2.0 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 CBZ35565.1 - 0.005 17.2 8.4 0.96 9.9 3.7 2.5 2 0 0 2 2 2 2 Syntaxin-like protein bact-PGI_C PF10432.9 CBZ35565.1 - 0.037 14.1 0.6 0.059 13.4 0.6 1.4 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal SIS domain ETRAMP PF09716.10 CBZ35565.1 - 0.092 12.8 0.5 0.72 9.9 0.0 2.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF2207 PF09972.9 CBZ35565.1 - 0.16 10.7 3.7 0.087 11.6 1.0 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Amnionless PF14828.6 CBZ35565.1 - 0.16 10.7 3.7 0.18 10.6 2.6 1.7 1 1 0 1 1 1 0 Amnionless DUF2400 PF09674.10 CBZ35565.1 - 1.4 8.9 5.8 0.15 12.1 0.5 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) PTRF_SDPR PF15237.6 CBZ35565.1 - 1.5 8.4 10.6 2.6 7.6 10.6 1.6 1 1 0 1 1 1 0 PTRF/SDPR family CEP19 PF14933.6 CBZ35565.1 - 3.8 7.8 9.7 0.45 10.8 2.1 2.6 1 1 2 3 3 3 0 CEP19-like protein Shisa PF13908.6 CBZ35565.1 - 6.4 7.0 6.2 0.8 9.9 0.4 2.1 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF423 PF04241.15 CBZ35566.1 - 2.8e-14 53.1 2.1 4.5e-14 52.4 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) NOG1 PF06858.14 CBZ35566.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) DUF423 PF04241.15 CBZ35567.1 - 1.1e-15 57.6 0.8 1.5e-15 57.1 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) GerA PF03323.13 CBZ35567.1 - 0.041 12.3 0.4 0.076 11.5 0.1 1.5 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein DUF423 PF04241.15 CBZ35568.1 - 3.1e-20 72.2 2.1 5.5e-20 71.4 2.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF423) CaM_binding PF07839.11 CBZ35569.1 - 0.11 13.3 0.5 15 6.3 0.0 2.2 2 0 0 2 2 2 0 Plant calmodulin-binding domain MSP1_C PF07462.11 CBZ35569.1 - 0.14 10.8 1.3 0.16 10.6 1.3 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4551 PF15087.6 CBZ35569.1 - 2.3 7.0 4.1 2.6 6.8 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DEAD PF00270.29 CBZ35571.1 - 1.7e-43 148.4 0.0 1.1e-42 145.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ35571.1 - 1.3e-30 106.0 0.1 8.8e-30 103.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CBZ35571.1 - 0.002 17.5 0.0 0.0048 16.3 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 CBZ35571.1 - 0.0036 17.3 0.0 0.025 14.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ35571.1 - 0.047 12.9 0.1 0.065 12.4 0.1 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 CBZ35571.1 - 0.16 12.3 0.7 0.5 10.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain Coa1 PF08695.10 CBZ35573.1 - 0.0054 16.5 0.0 0.016 15.0 0.0 1.8 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2046 PF09755.9 CBZ35574.1 - 0.1 11.8 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) DNA_repr_REX1B PF14966.6 CBZ35574.1 - 0.51 11.0 2.3 1.2 9.8 0.1 2.3 2 0 0 2 2 2 0 DNA repair REX1-B Abhydrolase_1 PF00561.20 CBZ35575.1 - 1.6e-17 64.1 0.0 1.4e-15 57.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CBZ35575.1 - 1.4e-14 54.0 0.0 3e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ35575.1 - 2.5e-11 44.6 0.1 3.2e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 CBZ35575.1 - 0.00039 19.2 0.2 0.0023 16.7 0.2 1.9 1 1 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 CBZ35575.1 - 0.00048 19.7 0.4 0.03 13.8 0.0 2.9 3 1 1 4 4 4 1 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 CBZ35575.1 - 0.00085 19.4 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_2 PF02230.16 CBZ35575.1 - 0.001 19.0 0.1 0.019 14.8 0.0 2.5 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CBZ35575.1 - 0.008 15.9 0.0 0.027 14.1 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Esterase_phd PF10503.9 CBZ35575.1 - 0.026 14.0 0.4 0.83 9.1 0.3 2.1 1 1 1 2 2 2 0 Esterase PHB depolymerase Peptidase_S15 PF02129.18 CBZ35575.1 - 0.031 13.9 0.0 3.6 7.1 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 CBZ35575.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 CBZ35575.1 - 0.16 11.5 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family TPP_enzyme_N PF02776.18 CBZ35576.1 - 2e-13 50.3 0.9 6.2e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CBZ35576.1 - 1.8e-10 40.8 3.5 2.4e-09 37.1 1.1 3.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Kelch_3 PF13415.6 CBZ35577.1 - 6.4e-16 58.2 0.7 3.7e-06 27.1 0.0 4.0 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_4 PF13418.6 CBZ35577.1 - 4.4e-14 52.2 0.4 3.5e-06 26.9 0.0 3.6 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CBZ35577.1 - 3.7e-12 46.1 0.6 2.8e-05 24.2 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 CBZ35577.1 - 4e-12 45.8 0.4 5.9e-05 22.9 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CBZ35577.1 - 1.2e-10 41.0 2.8 0.0018 18.2 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CBZ35577.1 - 4.2e-10 39.0 2.4 0.00013 21.4 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Helicase_C_2 PF13307.6 CBZ35578.1 - 5.1e-45 153.7 0.0 8.9e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBZ35578.1 - 1.1e-36 126.1 0.0 1.9e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 CBZ35578.1 - 3.8e-05 23.8 0.0 0.033 14.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CBZ35578.1 - 0.00057 19.7 0.0 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase TruD PF01142.18 CBZ35580.1 - 6.3e-28 97.7 0.0 2.8e-27 95.6 0.0 1.8 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) DUF3342 PF11822.8 CBZ35581.1 - 2.9e-38 130.0 0.0 5.3e-38 129.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) DUF2756 PF10956.8 CBZ35582.1 - 0.2 12.1 0.3 0.45 11.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2756) Pkinase PF00069.25 CBZ35583.1 - 0.014 14.7 0.0 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein kinase domain APH PF01636.23 CBZ35583.1 - 0.099 12.5 3.2 0.15 12.0 0.3 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 CBZ35585.1 - 1.7e-63 214.4 0.0 2.6e-63 213.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Lipocalin_5 PF13924.6 CBZ35585.1 - 3.2e-34 117.8 0.0 5.7e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain Pkinase_Tyr PF07714.17 CBZ35585.1 - 6.8e-34 117.3 0.0 1.1e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PX PF00787.24 CBZ35585.1 - 8.2e-14 51.6 0.2 1.8e-13 50.4 0.2 1.5 1 0 0 1 1 1 1 PX domain Kinase-like PF14531.6 CBZ35585.1 - 0.00022 20.7 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FYVE PF01363.21 CBZ35585.1 - 0.00035 20.7 2.4 0.0011 19.1 2.4 1.9 1 0 0 1 1 1 1 FYVE zinc finger APH PF01636.23 CBZ35585.1 - 0.0013 18.7 2.4 0.021 14.8 0.2 3.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ35585.1 - 0.079 12.3 0.1 0.19 11.1 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CBZ35585.1 - 0.19 11.4 0.0 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 zf-CRD PF17979.1 CBZ35585.1 - 1.9 8.6 5.7 1.8 8.6 3.4 2.2 2 0 0 2 2 2 0 Cysteine rich domain with multizinc binding regions Sulfate_transp PF00916.20 CBZ35586.1 - 1.8e-45 155.4 21.4 2.8e-45 154.7 21.4 1.3 1 0 0 1 1 1 1 Sulfate permease family His_Phos_2 PF00328.22 CBZ35586.1 - 1.3e-16 60.9 0.0 7e-14 52.0 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) STAS PF01740.21 CBZ35586.1 - 6.2e-08 32.3 0.0 1.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CBZ35586.1 - 0.0074 16.7 4.1 0.0074 16.7 4.1 2.6 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily DUF3947 PF13135.6 CBZ35586.1 - 0.83 9.9 4.1 2.3 8.5 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) DZR PF12773.7 CBZ35587.1 - 0.64 10.1 5.6 0.13 12.3 1.6 1.9 2 1 0 2 2 2 0 Double zinc ribbon zf-HIT PF04438.16 CBZ35587.1 - 2.2 8.3 7.3 4.3 7.3 7.3 1.5 1 0 0 1 1 1 0 HIT zinc finger RPN2_C PF18004.1 CBZ35590.1 - 2e-28 99.4 0.0 3.4e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CBZ35590.1 - 7.7e-16 57.6 8.1 0.17 12.4 0.0 8.5 7 0 0 7 7 7 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CBZ35590.1 - 7.9e-15 55.0 3.2 4.7e-11 42.9 0.0 4.6 4 1 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 CBZ35590.1 - 0.00063 19.8 0.2 1.3 9.0 0.0 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 TPR_14 PF13428.6 CBZ35590.1 - 0.0046 17.7 1.0 6.4 7.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ35590.1 - 0.12 12.6 5.8 1.4e+02 3.1 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ35590.1 - 2.7 8.3 8.7 8.1 6.8 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ35590.1 - 3.7 8.5 9.9 36 5.4 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 CBZ35591.1 - 1.4e-28 99.9 0.1 4.8e-15 55.7 0.1 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_30 PF05430.11 CBZ35592.1 - 0.0049 16.8 0.0 0.0092 15.9 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 CBZ35593.1 - 9.9e-11 41.5 0.0 1.1e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35593.1 - 0.0064 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ35593.1 - 0.013 15.4 0.0 0.038 13.9 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 CBZ35593.1 - 0.014 16.2 4.3 4.2 8.4 0.1 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat RIO1 PF01163.22 CBZ35593.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Sporozoite_P67 PF05642.11 CBZ35593.1 - 3.4 5.6 7.2 6.1 4.8 7.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ArfGap PF01412.18 CBZ35594.1 - 3.7e-12 46.4 0.0 5.2e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Topoisom_bac PF01131.20 CBZ35595.1 - 5.2e-111 371.6 0.0 6.4e-111 371.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CBZ35595.1 - 3.3e-17 62.6 0.0 5.7e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Toprim domain OrfB_Zn_ribbon PF07282.11 CBZ35595.1 - 0.28 11.2 5.0 13 5.8 0.2 3.5 3 0 0 3 3 3 0 Putative transposase DNA-binding domain AAA PF00004.29 CBZ35596.1 - 1.1e-31 110.0 0.0 1.6e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ35596.1 - 4.4e-06 27.0 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ35596.1 - 1e-05 26.0 0.0 2.8e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CBZ35596.1 - 2e-05 25.2 0.0 4e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBZ35596.1 - 2.4e-05 24.5 0.0 4.8e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBZ35596.1 - 0.0006 19.6 0.0 0.0022 17.8 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 CBZ35596.1 - 0.00067 19.7 0.0 0.0021 18.0 0.0 1.9 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CBZ35596.1 - 0.001 19.4 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CBZ35596.1 - 0.0011 18.7 0.0 0.0035 17.1 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CBZ35596.1 - 0.0012 19.2 0.0 0.0046 17.3 0.0 1.9 2 0 0 2 2 2 1 RNA helicase Cytidylate_kin PF02224.18 CBZ35596.1 - 0.0012 18.6 0.1 0.0025 17.6 0.1 1.6 1 1 0 1 1 1 1 Cytidylate kinase AAA_11 PF13086.6 CBZ35596.1 - 0.0044 16.8 0.0 0.0071 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CBZ35596.1 - 0.0053 16.8 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CBZ35596.1 - 0.0065 16.0 0.0 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 CBZ35596.1 - 0.017 14.8 0.0 0.061 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ35596.1 - 0.048 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 CBZ35596.1 - 0.093 13.2 0.1 0.23 11.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CBZ35596.1 - 0.096 12.3 0.3 1.7 8.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.10 CBZ35596.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Rad17 PF03215.15 CBZ35596.1 - 0.14 12.1 0.0 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain TIP49 PF06068.13 CBZ35596.1 - 0.14 11.3 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 CBZ35596.1 - 0.21 11.7 0.0 0.85 9.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) PduV-EutP PF10662.9 CBZ35596.1 - 0.24 11.1 0.0 0.64 9.8 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Rep_fac-A_C PF08646.10 CBZ35599.1 - 7e-41 139.4 0.7 1.7e-39 134.9 0.2 2.7 3 0 0 3 3 3 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CBZ35599.1 - 2e-22 79.0 1.8 1.6e-20 72.9 0.7 2.5 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 CBZ35599.1 - 1.5e-12 47.3 0.5 7.2e-09 35.5 0.0 2.9 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CBZ35599.1 - 3.5e-07 30.2 0.0 1.5e-05 24.8 0.0 2.6 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 tRNA_anti_2 PF13742.6 CBZ35599.1 - 0.031 14.5 0.0 0.099 12.9 0.0 1.8 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain DZR PF12773.7 CBZ35599.1 - 0.04 14.0 1.5 0.074 13.1 1.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 CBZ35599.1 - 0.051 13.6 1.0 0.1 12.6 1.0 1.4 1 0 0 1 1 1 0 zinc-ribbons zf_UBZ PF18439.1 CBZ35599.1 - 0.1 12.2 2.5 2.9 7.6 0.3 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger OrfB_Zn_ribbon PF07282.11 CBZ35599.1 - 0.63 10.0 2.9 1.3 9.0 2.9 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain SNF2_N PF00176.23 CBZ35600.1 - 6.5e-56 189.5 0.0 1.5e-55 188.3 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ35600.1 - 6.3e-11 42.6 0.0 1.3e-09 38.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 CBZ35600.1 - 2e-09 37.1 9.7 2e-09 37.1 9.7 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ35600.1 - 2e-09 37.1 10.2 2e-09 37.1 10.2 3.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ35600.1 - 1.1e-08 35.2 10.5 1.1e-08 35.2 10.5 4.0 4 0 0 4 4 3 1 Ring finger domain Prok-RING_4 PF14447.6 CBZ35600.1 - 2.4e-08 33.7 9.2 2.4e-08 33.7 9.2 3.3 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBZ35600.1 - 3.6e-08 33.3 7.2 1.1e-07 31.7 7.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ35600.1 - 1.1e-07 31.6 11.2 1.1e-07 31.6 11.2 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ35600.1 - 2e-06 27.6 9.5 2e-06 27.6 9.5 3.6 3 0 0 3 3 3 1 zinc-RING finger domain ResIII PF04851.15 CBZ35600.1 - 9.6e-06 25.7 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 CBZ35600.1 - 0.0023 18.1 9.5 0.0023 18.1 9.5 2.7 3 0 0 3 3 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBZ35600.1 - 0.0031 17.8 7.5 0.0031 17.8 7.5 2.9 3 0 0 3 3 1 1 RING-H2 zinc finger domain zf-RanBP PF00641.18 CBZ35600.1 - 0.0074 15.6 2.1 0.0074 15.6 2.1 3.3 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others zf-RING_11 PF17123.5 CBZ35600.1 - 0.024 14.4 7.5 0.059 13.1 7.5 1.8 1 0 0 1 1 1 0 RING-like zinc finger DEAD PF00270.29 CBZ35600.1 - 0.029 14.2 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase DZR PF12773.7 CBZ35600.1 - 0.93 9.6 22.8 0.38 10.8 0.7 3.5 2 1 1 3 3 3 0 Double zinc ribbon zf-RING_6 PF14835.6 CBZ35600.1 - 8.4 6.3 9.2 0.6 10.0 2.9 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Aldolase_II PF00596.21 CBZ35601.1 - 2.2e-41 141.9 0.0 2.4e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Kinesin PF00225.23 CBZ35602.1 - 3.5e-87 292.4 0.1 5.3e-87 291.8 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ35602.1 - 1.1e-35 122.8 0.0 8.9e-29 100.4 0.0 2.6 2 0 0 2 2 2 2 Microtubule binding bZIP_1 PF00170.21 CBZ35602.1 - 0.044 13.9 4.6 0.43 10.7 0.3 2.7 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 CBZ35602.1 - 0.18 12.3 18.4 0.65 10.5 0.7 3.4 2 1 2 4 4 4 0 Cell division protein ZapB AAA_13 PF13166.6 CBZ35602.1 - 0.24 10.0 9.6 0.46 9.1 9.6 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ35602.1 - 1.2 9.5 6.9 9.7 6.5 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain DUF4586 PF15239.6 CBZ35603.1 - 6.3e-38 131.7 1.7 8.6e-38 131.2 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Methyltransf_16 PF10294.9 CBZ35604.1 - 1.3e-13 51.0 0.4 2.3e-10 40.5 0.3 3.2 2 1 0 2 2 2 2 Lysine methyltransferase FAM86 PF14904.6 CBZ35604.1 - 0.042 13.9 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function RIBIOP_C PF04950.12 CBZ35605.1 - 2e-77 260.5 0.0 2e-77 260.5 0.0 1.7 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CBZ35605.1 - 1.9e-22 79.1 0.0 7.6e-22 77.2 0.0 2.1 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 CBZ35605.1 - 7.9e-05 23.0 0.0 0.00025 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ35605.1 - 0.00037 20.9 0.4 0.00093 19.6 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_30 PF13604.6 CBZ35605.1 - 0.00052 19.8 0.7 0.00095 18.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.23 CBZ35605.1 - 0.002 18.2 0.1 0.0076 16.3 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ35605.1 - 0.0023 17.5 0.0 0.13 11.7 0.0 2.7 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA PF00004.29 CBZ35605.1 - 0.0026 18.2 0.0 0.0067 16.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CBZ35605.1 - 0.0077 16.7 0.1 0.06 13.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 CBZ35605.1 - 0.022 14.9 1.7 0.046 13.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 CBZ35605.1 - 0.023 14.6 0.1 0.045 13.6 0.1 1.4 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 CBZ35605.1 - 0.024 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 CBZ35605.1 - 0.026 14.9 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CBZ35605.1 - 0.029 14.4 0.0 0.085 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 CBZ35605.1 - 0.046 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 CBZ35605.1 - 0.049 14.2 1.3 0.2 12.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 CBZ35605.1 - 0.052 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 CBZ35605.1 - 0.053 12.7 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 CBZ35605.1 - 0.39 11.2 3.7 27 5.2 0.9 3.0 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 CBZ35605.1 - 0.59 9.9 0.0 0.59 9.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain DHHC PF01529.20 CBZ35606.1 - 1.7e-23 83.2 12.7 1.7e-23 83.2 12.7 2.5 3 0 0 3 3 3 1 DHHC palmitoyltransferase MFS_2 PF13347.6 CBZ35606.1 - 3.1 6.2 14.0 0.041 12.4 6.7 1.4 2 0 0 2 2 2 0 MFS/sugar transport protein DnaJ PF00226.31 CBZ35607.1 - 3.6e-08 33.4 0.0 8.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain BCIP PF13862.6 CBZ35608.1 - 1.7e-30 106.3 0.0 2.9e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 p21-C-terminal region-binding protein dsDNA_bind PF01984.20 CBZ35609.1 - 6.6e-19 68.2 12.3 8.3e-19 67.9 12.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain HTH_40 PF14493.6 CBZ35609.1 - 0.087 13.3 0.9 0.32 11.5 0.1 2.0 1 1 1 2 2 2 0 Helix-turn-helix domain UPF0154 PF03672.13 CBZ35609.1 - 0.19 11.8 4.8 2.7 8.1 0.1 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) DUF2870 PF11069.8 CBZ35609.1 - 0.45 10.9 5.0 0.27 11.7 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) DUF1749 PF08538.10 CBZ35609.1 - 2.1 7.4 4.6 0.84 8.7 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) Zip PF02535.22 CBZ35610.1 - 7.7e-43 147.0 10.8 7.7e-43 147.0 10.8 2.2 2 1 0 2 2 2 2 ZIP Zinc transporter CorA PF01544.18 CBZ35611.1 - 0.00012 21.5 5.2 0.0003 20.2 5.2 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CorA PF01544.18 CBZ35612.1 - 0.00012 21.5 5.2 0.0003 20.2 5.2 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_S15 PF02129.18 CBZ35613.1 - 8.1e-60 202.7 0.1 5.9e-59 199.9 0.2 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 CBZ35613.1 - 8e-34 117.5 0.0 1.1e-33 117.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Hydrolase_4 PF12146.8 CBZ35613.1 - 1e-08 34.8 0.1 2.6e-07 30.2 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ35613.1 - 1.3e-06 28.3 0.1 2e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CBZ35613.1 - 1.1e-05 25.0 1.0 6.7e-05 22.5 0.2 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 CBZ35613.1 - 0.00016 20.5 0.0 0.00048 18.9 0.0 1.7 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 CBZ35613.1 - 0.08 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family GTP_EFTU PF00009.27 CBZ35614.1 - 4.6e-42 143.8 0.0 8.6e-42 142.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBZ35614.1 - 8.6e-20 70.6 0.0 1.7e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CBZ35614.1 - 2.1e-12 46.9 0.1 4.5e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus RF3_C PF16658.5 CBZ35614.1 - 2.5e-06 27.3 0.1 6e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ35614.1 - 1.8e-05 25.0 0.0 5.4e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ35614.1 - 0.0015 18.6 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CBZ35614.1 - 0.014 14.8 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 AIG1 family EFG_IV PF03764.18 CBZ35614.1 - 0.056 13.2 0.0 0.57 10.0 0.0 2.5 3 0 0 3 3 3 0 Elongation factor G, domain IV FeoB_N PF02421.18 CBZ35614.1 - 0.069 12.7 0.0 0.23 11.0 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B LacAB_rpiB PF02502.18 CBZ35615.1 - 1.3e-50 171.0 0.5 1.5e-50 170.8 0.5 1.1 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 CBZ35615.1 - 0.02 14.9 0.2 0.032 14.3 0.2 1.5 1 1 0 1 1 1 0 Glycine-rich SFCGS LRR_6 PF13516.6 CBZ35617.1 - 2.7e-16 58.1 4.4 0.029 14.4 0.0 6.7 6 0 0 6 6 6 5 Leucine Rich repeat LRR_4 PF12799.7 CBZ35617.1 - 6.8e-10 39.0 3.0 0.018 15.4 0.0 4.6 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ35617.1 - 0.00024 20.8 9.9 0.2 11.4 0.8 5.2 4 2 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 CBZ35617.1 - 0.0018 18.5 1.6 79 4.4 0.0 5.4 5 1 1 6 6 6 0 Leucine Rich Repeat GAS PF13851.6 CBZ35617.1 - 0.12 11.7 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding COMP PF11598.8 CBZ35617.1 - 0.14 12.7 0.6 1.1 9.8 1.2 2.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein DuoxA PF10204.9 CBZ35618.1 - 0.037 13.0 1.7 0.045 12.8 1.7 1.1 1 0 0 1 1 1 0 Dual oxidase maturation factor CobD_Cbib PF03186.13 CBZ35618.1 - 0.23 10.6 2.4 0.29 10.3 2.4 1.1 1 0 0 1 1 1 0 CobD/Cbib protein Sec62 PF03839.16 CBZ35618.1 - 3.3 7.2 6.3 4.5 6.7 6.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Pkinase PF00069.25 CBZ35619.1 - 2.7e-53 181.0 0.0 5.7e-53 180.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35619.1 - 3e-26 92.2 0.0 4.4e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ35619.1 - 2.1e-05 23.5 0.0 5.5e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ35619.1 - 0.0013 18.7 0.2 0.24 11.3 0.1 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ35619.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 CBZ35619.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase NPCC PF08058.11 CBZ35619.1 - 0.12 12.5 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore complex component Kdo PF06293.14 CBZ35619.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family D123 PF07065.14 CBZ35620.1 - 0.0062 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 D123 GRIM-19 PF06212.12 CBZ35622.1 - 3.7e-09 36.6 0.2 5.2e-09 36.1 0.2 1.2 1 0 0 1 1 1 1 GRIM-19 protein DPCD PF14913.6 CBZ35623.1 - 1.7e-68 229.8 0.0 1.9e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 DPCD protein family AMP-binding PF00501.28 CBZ35624.1 - 7.4e-30 103.9 0.0 1.2e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Ank_2 PF12796.7 CBZ35624.1 - 1.3e-15 57.7 8.7 1.4e-08 35.2 0.3 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ35624.1 - 8.2e-14 51.8 1.0 2.6e-07 31.0 0.0 3.8 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ35624.1 - 4.2e-09 35.9 4.5 0.26 12.0 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CBZ35624.1 - 3.5e-07 30.4 7.2 0.029 14.7 0.1 4.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CBZ35624.1 - 1.3e-06 28.6 10.0 0.015 15.7 0.1 6.0 6 0 0 6 6 6 2 Ankyrin repeat PP-binding PF00550.25 CBZ35624.1 - 0.016 15.5 0.0 0.051 13.9 0.0 1.9 1 0 0 1 1 1 0 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CBZ35624.1 - 0.028 15.4 0.0 0.093 13.7 0.0 1.9 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain TruB_C PF09142.11 CBZ35624.1 - 0.055 13.2 0.7 0.2 11.5 0.7 2.0 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal RNA_pol_L_2 PF13656.6 CBZ35625.1 - 3.3e-24 84.4 0.0 4.7e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CBZ35625.1 - 0.00013 21.3 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sua5_yciO_yrdC PF01300.18 CBZ35626.1 - 9.4e-47 158.8 0.0 1.3e-46 158.3 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CBZ35626.1 - 4.5e-12 46.7 0.0 7.8e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DEAD PF00270.29 CBZ35627.1 - 1.9e-44 151.5 0.0 1.5e-43 148.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ35627.1 - 4.5e-27 94.6 0.0 3.8e-26 91.6 0.2 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ35627.1 - 4.6e-05 23.5 0.0 0.0002 21.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ35627.1 - 9.3e-05 21.8 0.1 0.00016 21.0 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase T4SS-DNA_transf PF02534.14 CBZ35627.1 - 0.012 14.5 0.0 0.025 13.4 0.0 1.4 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer PhoH PF02562.16 CBZ35627.1 - 0.012 15.1 0.1 5.6 6.4 0.0 2.9 2 1 1 3 3 3 0 PhoH-like protein CEP76-C2 PF15627.6 CBZ35628.1 - 1.4e-39 135.2 0.0 2.6e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 CEP76 C2 domain C2 PF00168.30 CBZ35628.1 - 0.0086 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Transglut_core PF01841.19 CBZ35628.1 - 0.1 13.1 0.0 0.54 10.7 0.0 2.2 3 0 0 3 3 3 0 Transglutaminase-like superfamily UPF0220 PF05255.11 CBZ35629.1 - 3.5e-14 52.7 0.7 4.2e-14 52.4 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) LptF_LptG PF03739.14 CBZ35629.1 - 0.5 9.2 7.8 1.9 7.3 1.4 2.0 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG PrgI PF12666.7 CBZ35629.1 - 0.78 10.5 4.3 0.82 10.4 0.3 2.1 2 0 0 2 2 2 0 PrgI family protein GDPD PF03009.17 CBZ35630.1 - 7.6e-20 71.7 0.0 5.9e-17 62.2 0.0 2.1 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 CBZ35630.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Cullin PF00888.22 CBZ35631.1 - 3.9e-42 144.7 1.7 4.8e-42 144.4 1.7 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBZ35631.1 - 1.3e-09 37.9 0.4 8.3e-09 35.4 0.1 2.6 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 CBZ35631.1 - 0.0081 16.5 0.0 0.055 13.8 0.0 2.5 2 0 0 2 2 2 1 Penicillinase repressor TrmB PF01978.19 CBZ35631.1 - 0.013 15.4 0.6 0.23 11.4 0.0 2.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Cullin PF00888.22 CBZ35632.1 - 2.2e-37 129.0 0.0 6.7e-37 127.4 0.0 1.7 1 1 0 1 1 1 1 Cullin family Penicillinase_R PF03965.16 CBZ35632.1 - 0.00055 20.3 0.2 0.0036 17.6 0.1 2.4 2 0 0 2 2 2 1 Penicillinase repressor Cullin_Nedd8 PF10557.9 CBZ35632.1 - 0.0021 18.0 0.4 0.0085 16.1 0.1 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_20 PF12840.7 CBZ35632.1 - 0.0053 16.8 0.6 4.7 7.3 0.1 3.8 4 0 0 4 4 4 1 Helix-turn-helix domain EAP30 PF04157.16 CBZ35632.1 - 0.049 12.9 0.2 0.32 10.3 0.1 2.0 1 1 0 2 2 2 0 EAP30/Vps36 family HTH_DeoR PF08220.12 CBZ35632.1 - 0.14 11.9 0.6 2 8.3 0.1 2.5 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Dynein_light PF01221.18 CBZ35633.1 - 1.9e-32 111.4 0.0 2.1e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 PapC_C PF13953.6 CBZ35633.1 - 0.049 13.4 0.0 0.15 11.9 0.1 1.6 2 0 0 2 2 2 0 PapC C-terminal domain TINF2_N PF14973.6 CBZ35633.1 - 0.12 12.7 0.0 0.14 12.5 0.0 1.1 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus HhH-GPD PF00730.25 CBZ35634.1 - 5e-19 68.8 0.0 3.6e-18 66.0 0.0 2.3 2 1 1 3 3 3 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 CBZ35634.1 - 7.3e-12 45.2 0.0 2.9e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 NUDIX domain HHH PF00633.23 CBZ35634.1 - 1.3e-05 24.8 0.1 5e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 CBZ35634.1 - 0.0087 16.6 0.1 0.49 11.0 0.0 3.2 4 0 0 4 4 4 1 Helix-hairpin-helix domain HHH_2 PF12826.7 CBZ35634.1 - 0.018 15.1 0.0 7.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Whib PF02467.16 CBZ35634.1 - 2.6 8.7 5.6 4.5 7.9 2.1 2.8 2 1 0 2 2 2 0 Transcription factor WhiB Kelch_6 PF13964.6 CBZ35635.1 - 6e-08 32.7 0.0 0.0034 17.6 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 CBZ35635.1 - 2.3e-05 24.3 0.1 0.017 15.2 0.0 3.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ35635.1 - 6.8e-05 22.4 0.0 0.13 11.9 0.0 2.6 2 0 0 2 2 2 2 Kelch motif APS-reductase_C PF12139.8 CBZ35635.1 - 0.00038 20.6 0.0 0.0014 18.8 0.0 1.9 2 0 0 2 2 2 1 Adenosine-5'-phosphosulfate reductase beta subunit Kelch_2 PF07646.15 CBZ35635.1 - 0.0016 18.3 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 Kelch motif DUF5546 PF17700.1 CBZ35635.1 - 0.0091 16.4 1.0 0.015 15.6 0.5 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5546) Kelch_3 PF13415.6 CBZ35635.1 - 0.011 16.0 0.0 0.12 12.7 0.0 2.8 2 0 0 2 2 2 0 Galactose oxidase, central domain Methyltransf_25 PF13649.6 CBZ35636.1 - 5.2e-07 30.3 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ35636.1 - 1.4e-05 25.6 0.0 3.8e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ35636.1 - 2.2e-05 24.3 0.0 2.9e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ35636.1 - 8.6e-05 23.2 0.0 0.00015 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ35636.1 - 0.0081 16.0 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CBZ35636.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ROS_MUCR PF05443.11 CBZ35637.1 - 0.3 11.1 3.7 0.22 11.6 0.3 2.3 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein CorA PF01544.18 CBZ35637.1 - 0.32 10.3 1.6 0.53 9.6 1.6 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Sel1 PF08238.12 CBZ35637.1 - 0.45 11.3 7.5 0.53 11.1 0.1 3.6 4 0 0 4 4 4 0 Sel1 repeat CortBP2 PF09727.9 CBZ35639.1 - 0.0052 16.7 14.1 0.18 11.7 0.5 2.4 2 0 0 2 2 2 2 Cortactin-binding protein-2 HSA PF07529.13 CBZ35639.1 - 0.0082 16.4 2.6 0.028 14.7 2.6 1.9 1 0 0 1 1 1 1 HSA Prp19 PF08606.11 CBZ35639.1 - 0.036 14.1 0.1 0.036 14.1 0.1 2.4 3 0 0 3 3 3 0 Prp19/Pso4-like Jnk-SapK_ap_N PF09744.9 CBZ35639.1 - 0.14 12.4 15.9 0.79 9.9 1.9 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SAP30_Sin3_bdg PF13867.6 CBZ35639.1 - 0.19 12.1 1.0 0.4 11.1 1.0 1.5 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Macoilin PF09726.9 CBZ35639.1 - 0.48 8.9 14.0 0.14 10.7 0.9 2.5 2 0 0 2 2 2 0 Macoilin family TSNAXIP1_N PF15739.5 CBZ35639.1 - 0.92 9.9 6.9 1.7 9.1 0.6 2.7 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus LsmAD PF06741.13 CBZ35639.1 - 1.6 9.3 6.0 9.2 6.9 0.4 2.7 2 0 0 2 2 2 0 LsmAD domain JIP_LZII PF16471.5 CBZ35639.1 - 2.3 8.5 8.5 0.98 9.6 0.5 2.9 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II dCache_1 PF02743.18 CBZ35639.1 - 4.3 7.1 4.7 1.2 8.9 0.9 1.8 2 0 0 2 2 2 0 Cache domain Glyco_hydro_63 PF03200.16 CBZ35640.1 - 3.4e-49 167.9 0.1 1.7e-46 159.1 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CBZ35640.1 - 1.8e-17 64.2 0.2 4.1e-17 63.0 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Ribosomal_S14 PF00253.21 CBZ35641.1 - 2.5e-11 43.1 3.5 2.7e-11 43.0 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e PhosphMutase PF10143.9 CBZ35643.1 - 8.4e-46 155.9 0.0 1.8e-45 154.9 0.0 1.6 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 CBZ35643.1 - 3.1e-13 49.7 0.0 7.8e-13 48.4 0.0 1.6 1 1 0 1 1 1 1 Metalloenzyme superfamily GGACT PF06094.12 CBZ35643.1 - 1.5e-09 38.5 0.0 4.3e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Cyclin_N PF00134.23 CBZ35644.1 - 0.00025 20.8 0.1 0.00046 19.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain PEX11 PF05648.14 CBZ35646.1 - 0.00021 20.8 2.2 0.0004 19.9 2.2 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.14 CBZ35647.1 - 2.3e-19 69.8 0.7 5.2e-19 68.6 0.7 1.5 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MOZ_SAS PF01853.18 CBZ35648.1 - 4.1e-40 137.4 0.2 7.9e-22 77.8 0.3 3.1 3 0 0 3 3 3 3 MOZ/SAS family DNA_topoisoIV PF00521.20 CBZ35649.1 - 5.1e-130 434.2 0.0 7.8e-130 433.6 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CBZ35649.1 - 1.1e-42 145.3 0.2 3.4e-42 143.8 0.2 1.9 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CBZ35649.1 - 6.3e-21 74.6 0.1 1.6e-20 73.3 0.1 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CBZ35649.1 - 1.3e-09 38.5 0.0 3.7e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CBZ35649.1 - 0.00017 21.7 0.0 0.00059 20.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain DNA_gyraseB_C PF00986.21 CBZ35649.1 - 0.018 15.2 0.1 0.049 13.8 0.1 1.8 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus PBP1_TM PF14812.6 CBZ35649.1 - 0.47 10.9 25.8 0.14 12.6 5.3 4.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UPF0561 PF10573.9 CBZ35649.1 - 2.6 8.2 16.2 0.075 13.2 4.3 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Pap_E4 PF02711.14 CBZ35649.1 - 4.1 8.4 22.1 9.2 7.3 6.2 3.6 3 0 0 3 3 3 0 E4 protein Hexapep PF00132.24 CBZ35650.1 - 5.3e-06 25.9 7.0 0.00066 19.3 0.5 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 CBZ35650.1 - 0.0077 15.8 0.0 0.029 14.0 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase Fucokinase PF07959.12 CBZ35650.1 - 0.042 12.8 0.1 0.084 11.8 0.1 1.4 1 0 0 1 1 1 0 L-fucokinase Hexapep_2 PF14602.6 CBZ35650.1 - 0.049 13.4 5.7 0.2 11.4 0.4 3.3 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 CBZ35650.1 - 0.065 13.6 0.1 0.15 12.4 0.1 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain SR-25 PF10500.9 CBZ35650.1 - 0.51 9.9 12.5 0.086 12.4 4.4 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Cep57_MT_bd PF06657.13 CBZ35651.1 - 7.7e-05 23.1 2.4 0.0046 17.4 0.1 2.8 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.11 CBZ35651.1 - 0.012 15.8 2.6 6.5 6.9 3.7 2.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 CBZ35651.1 - 0.032 14.6 0.4 0.032 14.6 0.4 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF2408 PF10303.9 CBZ35651.1 - 0.067 13.7 0.2 0.22 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) HrpA_pilin PF09589.10 CBZ35651.1 - 0.078 13.7 0.1 0.18 12.5 0.1 1.5 1 0 0 1 1 1 0 HrpA pilus formation protein TMF_TATA_bd PF12325.8 CBZ35651.1 - 4.4 7.6 9.2 0.73 10.1 2.2 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding eIF3_N PF09440.10 CBZ35652.1 - 6.1e-12 46.1 2.7 1.7e-11 44.7 2.7 1.8 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 CBZ35652.1 - 5.5e-10 39.7 0.4 1.7e-09 38.1 0.4 1.9 2 0 0 2 2 2 1 PCI domain TPR_3 PF07720.12 CBZ35652.1 - 0.064 13.3 1.5 0.18 11.9 1.5 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PEP-utilisers_N PF05524.13 CBZ35652.1 - 0.56 10.4 2.6 2 8.6 0.4 2.7 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal CactinC_cactus PF09732.9 CBZ35654.1 - 1.1e-37 128.7 2.2 2e-37 127.9 2.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SHMT PF00464.19 CBZ35657.1 - 1.3e-172 573.9 0.0 1.6e-172 573.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CBZ35657.1 - 0.029 13.6 0.0 0.059 12.6 0.0 1.5 2 0 0 2 2 2 0 Beta-eliminating lyase MCM PF00493.23 CBZ35659.1 - 2.4e-91 304.8 0.3 3.6e-91 304.2 0.3 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ35659.1 - 2.9e-35 120.8 0.7 5.3e-35 120.0 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ35659.1 - 2.1e-21 76.1 5.1 2.5e-21 75.9 3.3 2.2 3 0 0 3 3 3 1 MCM AAA-lid domain MCM6_C PF18263.1 CBZ35659.1 - 1.1e-08 35.2 0.0 2.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 CBZ35659.1 - 2.1e-07 30.5 0.0 3.6e-06 26.5 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBZ35659.1 - 0.00045 20.2 0.2 0.0031 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 CBZ35659.1 - 0.0026 18.3 0.0 0.0066 17.0 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_3 PF07726.11 CBZ35659.1 - 0.0059 16.5 0.0 0.016 15.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBZ35659.1 - 0.0065 16.2 0.1 0.02 14.6 0.1 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AadA_C PF18280.1 CBZ35659.1 - 0.14 12.3 0.9 1.3 9.2 0.0 2.9 4 0 0 4 4 4 0 Aminoglycoside adenyltransferase C-terminal domain DUF188 PF02639.14 CBZ35659.1 - 0.16 11.7 0.9 9.6 5.9 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized BCR, YaiI/YqxD family COG1671 QRPTase_C PF01729.19 CBZ35659.1 - 0.55 10.0 4.0 0.64 9.8 0.4 2.6 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain WW PF00397.26 CBZ35660.1 - 3.9e-09 36.4 0.9 7.8e-09 35.5 0.9 1.5 1 0 0 1 1 1 1 WW domain GCD14 PF08704.10 CBZ35661.1 - 1.4e-62 211.6 1.8 4.4e-37 128.1 0.0 3.3 2 1 2 4 4 4 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CBZ35661.1 - 1.2e-07 31.6 0.0 2.6e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ35661.1 - 2.5e-06 28.1 0.1 0.0003 21.4 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CBZ35661.1 - 4.9e-05 23.2 0.0 0.00015 21.6 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.6 CBZ35661.1 - 0.0001 22.0 0.1 0.00051 19.8 0.1 2.1 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_11 PF08241.12 CBZ35661.1 - 0.0026 18.4 0.1 0.022 15.4 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 CBZ35661.1 - 0.0034 16.5 0.0 0.77 8.8 0.0 2.3 2 0 0 2 2 2 2 Fibrillarin Methyltransf_12 PF08242.12 CBZ35661.1 - 0.0074 17.0 0.1 0.13 13.1 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ35661.1 - 0.0099 15.2 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 CBZ35661.1 - 0.013 16.5 0.1 0.036 15.1 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CBZ35661.1 - 0.037 13.6 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain RrnaAD PF00398.20 CBZ35661.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltr_RsmB-F PF01189.17 CBZ35661.1 - 0.091 12.4 0.1 0.43 10.2 0.1 2.0 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Rft-1 PF04506.13 CBZ35662.1 - 3.1e-48 164.8 7.1 7.6e-42 143.7 3.4 2.4 2 1 0 2 2 2 2 Rft protein Herpes_ICP4_N PF03584.15 CBZ35662.1 - 0.033 14.0 0.2 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus ICP4-like protein N-terminal region 2-oxoacid_dh PF00198.23 CBZ35664.1 - 2.9e-80 269.1 0.3 3.7e-80 268.7 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CBZ35664.1 - 4e-20 71.4 1.8 6.6e-20 70.7 1.8 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CBZ35664.1 - 1e-05 25.3 0.4 0.041 13.7 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.19 CBZ35664.1 - 0.002 18.0 0.8 0.0038 17.1 0.8 1.4 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_D23 PF16576.5 CBZ35664.1 - 0.028 13.6 0.1 0.16 11.1 0.0 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CBZ35664.1 - 0.05 14.3 1.1 0.93 10.2 0.1 2.4 1 1 1 2 2 2 0 HlyD family secretion protein ATP-synt_ab PF00006.25 CBZ35665.1 - 4.3e-67 225.9 0.0 5.6e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CBZ35665.1 - 1.2e-14 54.5 1.5 2.4e-14 53.6 1.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NTP_transferase PF00483.23 CBZ35666.1 - 0.00026 20.7 0.0 0.00072 19.2 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 CBZ35666.1 - 0.00082 19.0 12.2 0.16 11.8 4.1 3.6 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 CBZ35666.1 - 0.0052 15.8 0.2 0.0083 15.1 0.2 1.2 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 CBZ35666.1 - 0.021 15.2 0.0 0.17 12.2 0.0 2.3 1 1 0 1 1 1 0 MobA-like NTP transferase domain DUF4954 PF16314.5 CBZ35666.1 - 0.11 10.5 1.9 0.36 8.9 1.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 CBZ35666.1 - 7.7 6.4 9.7 60 3.5 5.1 3.4 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase DUF676 PF05057.14 CBZ35667.1 - 8.3e-14 51.6 0.0 2.2e-12 47.0 0.0 2.4 2 1 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CBZ35667.1 - 0.0056 16.6 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Palmitoyl protein thioesterase VCBS PF13517.6 CBZ35668.1 - 1.1e-06 29.1 0.1 1.5 9.5 0.0 5.4 6 0 0 6 6 6 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CBZ35668.1 - 6.8e-06 26.1 0.3 0.0041 17.2 0.0 3.8 3 0 0 3 3 3 1 FG-GAP repeat TcdB_toxin_midN PF12256.8 CBZ35668.1 - 0.022 14.1 0.6 1.1 8.6 0.0 2.9 3 1 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region Ribosomal_S14 PF00253.21 CBZ35669.1 - 2.5e-11 43.1 3.5 2.7e-11 43.0 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e ParA PF10609.9 CBZ35670.1 - 1.2e-90 303.3 0.0 1.4e-90 303.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CBZ35670.1 - 1.4e-15 57.5 0.0 2.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CBZ35670.1 - 2.9e-11 43.6 3.1 9e-10 38.7 3.1 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CBZ35670.1 - 1.5e-08 34.2 1.1 7.9e-08 31.9 1.1 1.9 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 CBZ35670.1 - 2.5e-05 23.9 0.0 0.00041 19.9 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 CBZ35670.1 - 5.9e-05 22.5 0.2 0.00013 21.4 0.1 1.5 2 0 0 2 2 2 1 VirC1 protein ArsA_ATPase PF02374.15 CBZ35670.1 - 0.00023 20.5 0.6 0.0017 17.6 0.6 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 CBZ35670.1 - 0.01 15.3 0.1 0.029 13.9 0.1 1.7 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_26 PF13500.6 CBZ35670.1 - 0.064 13.1 0.2 6.2 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1611 PF07755.11 CBZ35670.1 - 0.08 12.2 1.2 0.18 11.1 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain Myc_N PF01056.18 CBZ35672.1 - 0.23 11.3 7.2 2.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Myc amino-terminal region HNF-1_N PF04814.13 CBZ35672.1 - 7.3 7.2 7.0 4.9 7.7 1.3 2.3 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus IF4E PF01652.18 CBZ35673.1 - 2.3e-30 105.5 0.0 3.2e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E MRP-L20 PF12824.7 CBZ35673.1 - 0.059 13.5 1.2 0.12 12.5 1.2 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 Acyl-CoA_dh_C PF12806.7 CBZ35674.1 - 1.1e-23 83.7 1.4 2.4e-23 82.6 1.4 1.5 1 0 0 1 1 1 1 Acetyl-CoA dehydrogenase C-terminal like Acyl-CoA_dh_M PF02770.19 CBZ35674.1 - 3.5e-19 68.8 0.0 7.9e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CBZ35674.1 - 7.1e-19 68.5 3.7 7.3e-18 65.2 3.7 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CBZ35674.1 - 1e-10 42.2 0.0 2.6e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBZ35674.1 - 6.3e-06 26.5 0.0 1.7e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain R3H PF01424.22 CBZ35675.1 - 3.8e-10 39.6 0.3 8.4e-10 38.5 0.3 1.6 1 0 0 1 1 1 1 R3H domain ABC_trans_N PF14510.6 CBZ35675.1 - 3.1 8.5 0.0 3.1 8.5 0.0 3.2 3 1 0 3 3 3 0 ABC-transporter N-terminal PIF1 PF05970.14 CBZ35676.1 - 1.7e-29 103.1 0.2 1.7e-25 90.0 0.0 3.3 4 0 0 4 4 4 2 PIF1-like helicase AAA_30 PF13604.6 CBZ35676.1 - 7.5e-16 58.4 0.7 1.5e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CBZ35676.1 - 1.4e-06 28.7 0.0 4.9e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CBZ35676.1 - 2.2e-05 24.2 0.1 5.2e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CBZ35676.1 - 0.00011 22.0 0.0 0.31 10.7 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 CBZ35676.1 - 0.0017 18.8 1.0 0.009 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Rrn6 PF10214.9 CBZ35676.1 - 0.055 12.0 2.2 0.076 11.5 2.2 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor MobB PF03205.14 CBZ35676.1 - 0.092 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Herpes_Helicase PF02689.14 CBZ35676.1 - 0.096 10.6 0.5 5.8 4.7 0.0 2.1 2 0 0 2 2 2 0 Helicase DUF2075 PF09848.9 CBZ35676.1 - 0.23 10.6 0.0 0.53 9.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CBZ35676.1 - 0.47 10.3 1.1 0.7 9.8 0.2 1.7 2 0 0 2 2 2 0 NTPase HEAT_2 PF13646.6 CBZ35677.1 - 4.2e-07 30.3 26.1 5.7e-05 23.4 2.1 7.6 7 1 0 7 7 7 2 HEAT repeats HEAT PF02985.22 CBZ35677.1 - 0.00011 22.1 11.7 0.44 10.9 0.0 7.1 7 0 0 7 7 7 3 HEAT repeat IFRD PF05004.13 CBZ35677.1 - 0.011 14.9 0.5 0.011 14.9 0.5 2.7 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) TPR_2 PF07719.17 CBZ35678.1 - 1.5e-06 27.9 0.2 0.037 14.1 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ35678.1 - 0.00021 21.5 0.5 0.59 10.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat SET PF00856.28 CBZ35678.1 - 0.00022 21.6 0.0 0.00052 20.4 0.0 1.8 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.18 CBZ35678.1 - 0.0034 17.4 8.3 0.0034 17.4 8.3 2.4 2 0 0 2 2 2 1 MYND finger TPR_14 PF13428.6 CBZ35678.1 - 0.04 14.7 2.0 6.5 7.9 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn-ribbon_8 PF09723.10 CBZ35678.1 - 0.041 14.0 0.5 0.13 12.4 0.5 1.9 1 0 0 1 1 1 0 Zinc ribbon domain TPR_1 PF00515.28 CBZ35678.1 - 0.059 13.2 0.0 5.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ35678.1 - 0.1 13.2 4.2 0.12 13.1 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S17e PF00833.18 CBZ35679.1 - 3e-50 169.2 3.9 3.8e-50 168.9 3.9 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S17e PF00833.18 CBZ35680.1 - 3e-50 169.2 3.9 3.8e-50 168.9 3.9 1.1 1 0 0 1 1 1 1 Ribosomal S17 SF3b1 PF08920.10 CBZ35682.1 - 9.1e-08 32.6 0.2 2.2e-07 31.4 0.2 1.6 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 CBZ35682.1 - 1.9e-07 31.3 20.1 0.028 14.8 4.7 7.0 5 2 2 7 7 7 2 HEAT repeats UME PF08064.13 CBZ35682.1 - 4.4e-05 23.3 1.3 0.0035 17.2 0.1 3.8 4 0 0 4 4 4 1 UME (NUC010) domain DRIM PF07539.12 CBZ35682.1 - 0.0037 15.6 0.4 0.63 8.3 0.1 2.7 2 1 0 2 2 2 2 Down-regulated in metastasis NUC173 PF08161.12 CBZ35682.1 - 0.016 14.9 3.0 2.8 7.6 0.0 4.4 4 2 0 4 4 4 0 NUC173 domain Adaptin_N PF01602.20 CBZ35682.1 - 0.046 12.3 1.2 6.5 5.2 0.1 2.7 1 1 0 2 2 2 0 Adaptin N terminal region HEAT PF02985.22 CBZ35682.1 - 0.095 13.0 16.7 2.4 8.6 0.0 7.0 7 0 0 7 7 7 0 HEAT repeat DHO_dh PF01180.21 CBZ35682.1 - 0.1 11.8 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase CTD PF12815.7 CBZ35682.1 - 0.11 13.1 3.5 0.22 12.1 3.5 1.5 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 HEAT_EZ PF13513.6 CBZ35682.1 - 0.34 11.5 23.0 11 6.7 0.0 7.8 8 1 1 9 9 8 0 HEAT-like repeat Cnd1 PF12717.7 CBZ35682.1 - 0.59 10.2 7.5 2.2 8.3 0.5 4.2 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 LRR_4 PF12799.7 CBZ35683.1 - 3.7e-11 43.1 8.2 7e-05 23.1 0.2 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) IQ PF00612.27 CBZ35683.1 - 5.5e-10 38.2 9.9 1.1e-05 24.7 2.5 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif LRR_8 PF13855.6 CBZ35683.1 - 8.3e-07 28.7 15.4 0.0014 18.4 0.1 4.3 2 2 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 CBZ35683.1 - 0.0039 16.7 2.1 0.072 12.6 0.6 2.7 3 0 0 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 CBZ35683.1 - 0.022 15.2 8.0 4 8.4 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 CBZ35683.1 - 0.026 14.6 12.5 5.5 7.3 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeat ADP_ribosyl_GH PF03747.14 CBZ35684.1 - 2.2e-10 40.8 0.3 1.3e-06 28.4 0.1 2.4 2 1 0 2 2 2 2 ADP-ribosylglycohydrolase IQ PF00612.27 CBZ35685.1 - 1.2e-18 65.1 87.8 0.00069 19.2 0.1 14.4 14 0 0 14 14 14 10 IQ calmodulin-binding motif Fis1_TPR_C PF14853.6 CBZ35685.1 - 0.023 14.8 0.1 0.055 13.6 0.1 1.6 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 CBZ35685.1 - 1.3 9.2 5.1 1.3 9.2 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Adaptin_N PF01602.20 CBZ35686.1 - 1.3e-71 241.8 10.3 1.6e-71 241.5 10.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CBZ35686.1 - 2.3e-33 115.5 0.0 4.6e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CBZ35686.1 - 1.7e-22 79.7 0.0 3.6e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CBZ35686.1 - 4.6e-12 46.2 0.4 9.8e-06 25.9 0.0 4.6 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 CBZ35686.1 - 4.3e-05 23.6 7.8 0.0037 17.3 0.3 4.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CBZ35686.1 - 6.6e-05 22.8 5.0 11 6.6 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat MoaC PF01967.21 CBZ35688.1 - 6.2e-23 81.4 0.0 1.7e-22 80.0 0.0 1.8 1 0 0 1 1 1 1 MoaC family His_Phos_2 PF00328.22 CBZ35689.1 - 3.3e-09 36.6 0.1 8e-06 25.4 0.0 2.9 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) DUF1656 PF07869.12 CBZ35689.1 - 0.14 12.2 1.1 0.36 10.9 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) SelR PF01641.18 CBZ35690.1 - 1.7e-39 134.6 0.0 2e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 CBZ35690.1 - 0.00079 19.1 0.2 0.08 12.7 0.0 2.4 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein FYVE PF01363.21 CBZ35690.1 - 0.024 14.8 1.1 0.044 13.9 1.1 1.4 1 0 0 1 1 1 0 FYVE zinc finger Yippee-Mis18 PF03226.14 CBZ35690.1 - 0.025 14.8 1.1 0.25 11.6 1.1 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4796 PF16044.5 CBZ35690.1 - 0.037 13.6 0.1 0.067 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) zf_C2HC_14 PF18574.1 CBZ35690.1 - 0.047 13.5 0.9 0.099 12.5 0.1 2.0 2 0 0 2 2 2 0 C2HC Zing finger domain TF_Zn_Ribbon PF08271.12 CBZ35690.1 - 0.14 11.7 4.0 0.52 9.9 0.2 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding Endonuclease_7 PF02945.15 CBZ35690.1 - 0.21 11.5 1.9 1 9.3 1.9 2.1 1 1 0 1 1 1 0 Recombination endonuclease VII Metallophos PF00149.28 CBZ35691.1 - 9.4e-34 117.7 0.1 1.2e-33 117.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf_UBZ PF18439.1 CBZ35691.1 - 0.11 12.1 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger VitD-bind_III PF09164.10 CBZ35691.1 - 0.11 12.5 0.7 0.27 11.3 0.7 1.6 1 0 0 1 1 1 0 Vitamin D binding protein, domain III COX15-CtaA PF02628.15 CBZ35692.1 - 1.2e-103 346.6 11.6 1.4e-103 346.4 11.6 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein BAALC_N PF06989.12 CBZ35694.1 - 0.071 13.4 1.4 18 5.8 0.1 3.4 2 0 0 2 2 2 0 BAALC N-terminus 2OG-FeII_Oxy_2 PF13532.6 CBZ35695.1 - 0.00032 20.9 0.0 0.00049 20.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily APG12 PF04110.13 CBZ35696.1 - 0.12 12.8 0.0 0.94 9.9 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DUF179 PF02622.15 CBZ35697.1 - 6.3e-06 26.2 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 HSP70 PF00012.20 CBZ35698.1 - 2.4e-13 49.1 0.1 2.9e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 Hsp70 protein Asp_decarbox PF02261.16 CBZ35698.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 Aspartate decarboxylase WD40 PF00400.32 CBZ35700.1 - 1.1e-46 155.8 19.3 3.2e-08 34.1 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ35700.1 - 1.1e-12 48.0 0.3 0.011 16.1 0.0 4.2 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ35700.1 - 2.9e-09 36.1 2.9 0.016 13.9 0.2 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CBZ35700.1 - 4.7e-07 29.9 0.0 0.0009 19.2 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CBZ35700.1 - 6.6e-05 22.7 0.0 1.8 8.6 0.0 4.8 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CBZ35700.1 - 0.00018 20.6 1.3 0.015 14.3 0.4 3.4 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CBZ35700.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain PQQ_2 PF13360.6 CBZ35700.1 - 0.034 13.7 0.0 0.093 12.3 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain Cytochrom_D1 PF02239.16 CBZ35700.1 - 0.038 12.5 0.0 1 7.8 0.0 2.4 2 0 0 2 2 2 0 Cytochrome D1 heme domain GCP_C_terminal PF04130.13 CBZ35701.1 - 4.3e-40 138.1 8.9 8e-40 137.2 8.9 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CBZ35701.1 - 7.1e-34 117.8 0.5 1.9e-33 116.4 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal HSP70 PF00012.20 CBZ35702.1 - 1.2e-262 872.5 5.1 1.4e-262 872.3 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ35702.1 - 2.8e-14 52.7 0.1 3.8e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CBZ35702.1 - 0.037 13.7 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CBZ35702.1 - 0.077 12.0 0.5 2 7.3 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF4364 PF14277.6 CBZ35702.1 - 0.086 12.6 1.7 0.24 11.1 1.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) DUF5581 PF17744.1 CBZ35702.1 - 0.12 11.7 0.2 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5581) CENP-Q PF13094.6 CBZ35703.1 - 0.0038 17.4 2.4 0.0065 16.7 2.4 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit CCDC85 PF10226.9 CBZ35703.1 - 0.021 14.5 0.5 0.04 13.6 0.5 1.4 1 0 0 1 1 1 0 CCDC85 family Jnk-SapK_ap_N PF09744.9 CBZ35703.1 - 0.036 14.3 6.6 0.036 14.3 6.6 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Lebercilin PF15619.6 CBZ35703.1 - 0.058 13.0 8.1 0.42 10.2 6.4 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease EzrA PF06160.12 CBZ35703.1 - 0.059 11.6 3.6 0.099 10.8 3.6 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA HALZ PF02183.18 CBZ35703.1 - 0.095 12.9 10.5 0.88 9.8 0.1 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper YabA PF06156.13 CBZ35703.1 - 0.21 12.2 2.9 1.8 9.3 3.0 2.0 2 0 0 2 2 2 0 Initiation control protein YabA TSC22 PF01166.18 CBZ35703.1 - 0.55 10.6 3.5 11 6.5 0.1 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4407 PF14362.6 CBZ35703.1 - 0.88 8.9 5.2 1.1 8.5 5.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 CBZ35703.1 - 0.9 9.4 6.7 12 5.7 0.0 2.8 2 1 1 3 3 3 0 Septum formation initiator OmpH PF03938.14 CBZ35703.1 - 1.2 9.5 8.9 3.2 8.1 8.0 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ZapB PF06005.12 CBZ35703.1 - 4.8 7.7 11.5 8.7 6.9 7.7 2.3 2 1 0 2 2 2 0 Cell division protein ZapB betaPIX_CC PF16523.5 CBZ35703.1 - 8.5 6.3 9.0 6.6 6.6 3.1 2.7 3 0 0 3 3 3 0 betaPIX coiled coil Beta-lactamase PF00144.24 CBZ35704.1 - 1.2e-10 41.2 0.1 4e-10 39.5 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase FlgT_N PF16548.5 CBZ35705.1 - 0.053 14.1 0.1 0.12 13.0 0.1 1.6 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain HSP70 PF00012.20 CBZ35706.1 - 5.1e-193 642.5 5.5 6.3e-193 642.2 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ35706.1 - 3.5e-18 65.5 1.3 6.4e-15 54.8 0.2 2.5 2 0 0 2 2 2 2 MreB/Mbl protein Phage_TAC_11 PF11836.8 CBZ35706.1 - 0.002 18.2 0.1 0.023 14.8 0.0 2.5 2 0 0 2 2 2 1 Phage tail tube protein, GTA-gp10 BcrAD_BadFG PF01869.20 CBZ35706.1 - 0.0023 17.5 1.5 0.21 11.1 0.0 2.9 4 1 0 4 4 4 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 CBZ35706.1 - 0.0042 17.5 6.2 0.17 12.3 0.0 3.5 2 1 0 2 2 2 1 Cell division protein FtsA Tudor_RapA PF18337.1 CBZ35706.1 - 0.73 10.0 2.2 3.7 7.8 0.1 3.0 2 1 1 3 3 3 0 RapA N-terminal Tudor like domain F-box PF00646.33 CBZ35708.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 F-box domain Ldh_1_N PF00056.23 CBZ35709.1 - 2.7e-34 118.3 0.1 4.5e-34 117.6 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBZ35709.1 - 4.3e-28 98.3 0.0 7.2e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain AAA_6 PF12774.7 CBZ35711.1 - 2.6e-150 499.9 0.0 6.9e-150 498.5 0.0 1.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ35711.1 - 4.1e-105 352.1 1.8 4.1e-105 352.1 1.8 3.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ35711.1 - 2.2e-101 338.5 0.0 8e-101 336.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ35711.1 - 6.9e-83 278.4 0.0 8.8e-81 271.5 0.0 3.7 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ35711.1 - 8.8e-78 260.4 2.6 1.1e-76 256.8 0.1 3.0 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ35711.1 - 4.8e-71 238.0 0.5 5.2e-65 218.4 0.0 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ35711.1 - 1e-52 178.2 0.0 2.5e-52 177.0 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ35711.1 - 7.8e-43 145.4 0.0 3.5e-41 140.0 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBZ35711.1 - 9e-41 140.0 11.2 1.7e-40 139.1 11.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CBZ35711.1 - 1.4e-25 89.9 0.0 5.9e-25 87.8 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CBZ35711.1 - 3.8e-24 85.2 0.0 1.8e-06 28.0 0.0 6.1 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 CBZ35711.1 - 4.2e-12 46.2 0.1 1.5e-11 44.3 0.0 2.1 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 CBZ35711.1 - 1.3e-08 35.3 0.3 0.057 13.9 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ35711.1 - 3.2e-06 27.6 7.2 4.2 7.7 0.0 7.3 6 1 0 6 6 6 2 AAA ATPase domain AAA_18 PF13238.6 CBZ35711.1 - 3.4e-05 24.4 0.0 0.088 13.4 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 CBZ35711.1 - 0.00031 21.0 8.8 3 8.1 0.0 6.0 6 0 0 6 6 5 1 AAA domain AAA_14 PF13173.6 CBZ35711.1 - 0.0014 18.6 0.0 0.78 9.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CBZ35711.1 - 0.0021 17.8 0.3 0.64 9.7 0.0 3.8 4 0 0 4 4 4 1 Sigma-54 interaction domain RNA_helicase PF00910.22 CBZ35711.1 - 0.0021 18.4 0.0 0.38 11.2 0.0 4.2 4 0 0 4 4 4 1 RNA helicase ResIII PF04851.15 CBZ35711.1 - 0.028 14.4 1.1 0.82 9.6 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CBZ35711.1 - 0.038 13.9 2.5 2.5 8.0 0.0 4.0 4 0 0 4 4 3 0 NACHT domain AAA_lid_7 PF17867.1 CBZ35711.1 - 0.085 13.1 0.1 0.47 10.7 0.1 2.3 1 0 0 1 1 1 0 Midasin AAA lid domain Mg_chelatase PF01078.21 CBZ35711.1 - 0.094 12.1 1.0 1.8 7.9 0.0 3.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CBZ35711.1 - 0.16 12.1 0.8 62 3.7 0.0 4.4 4 0 0 4 4 3 0 AAA domain Microtub_bd PF16796.5 CBZ35711.1 - 0.39 10.7 1.7 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 Microtubule binding SRP54 PF00448.22 CBZ35711.1 - 1.3 8.6 4.7 29 4.2 0.2 4.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CBZ35711.1 - 1.5 9.1 4.8 59 4.0 0.0 4.7 5 0 0 5 5 4 0 AAA domain Dor1 PF04124.12 CBZ35713.1 - 5.8e-23 81.1 7.2 7.9e-23 80.7 7.2 1.1 1 0 0 1 1 1 1 Dor1-like family Exo84_C PF16528.5 CBZ35713.1 - 1.4e-06 28.3 0.7 2.4e-06 27.5 0.3 1.6 1 1 0 1 1 1 1 Exocyst component 84 C-terminal TPR_16 PF13432.6 CBZ35713.1 - 0.98 10.1 4.8 0.42 11.3 0.7 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ELFV_dehydrog PF00208.21 CBZ35714.1 - 4.9e-88 295.0 4.4 6.6e-88 294.5 4.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CBZ35714.1 - 5.3e-50 168.7 0.0 1.5e-49 167.2 0.0 1.8 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 CBZ35714.1 - 0.00037 20.9 0.1 0.00068 20.0 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 CBZ35714.1 - 0.001 18.5 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Na_sulph_symp PF00939.19 CBZ35716.1 - 5e-19 68.7 45.7 4.7e-18 65.5 45.7 2.8 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CBZ35716.1 - 2.4e-17 63.1 46.2 2.4e-17 63.1 46.2 1.6 1 1 1 2 2 2 1 Citrate transporter SPX PF03105.19 CBZ35716.1 - 6.1e-07 29.7 8.2 3.4e-06 27.2 0.4 2.4 1 1 2 3 3 3 2 SPX domain zf-CCCH_4 PF18044.1 CBZ35718.1 - 0.015 15.1 0.6 0.015 15.1 0.6 2.3 2 1 0 2 2 2 0 CCCH-type zinc finger zf-CCCH PF00642.24 CBZ35718.1 - 0.071 13.0 5.7 3.7 7.6 0.3 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ35718.1 - 2.4 8.3 9.0 0.19 11.9 2.3 2.3 2 0 0 2 2 2 0 Zinc finger domain WD40 PF00400.32 CBZ35719.1 - 0.037 14.9 9.9 17 6.5 0.1 5.3 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF2828 PF11443.8 CBZ35719.1 - 0.062 11.4 0.0 0.11 10.5 0.0 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF1192 PF06698.11 CBZ35723.1 - 0.018 15.1 2.6 0.035 14.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Glycolipid_bind PF06475.11 CBZ35723.1 - 0.042 13.4 0.1 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 Putative glycolipid-binding DUF3323 PF11796.8 CBZ35723.1 - 0.092 12.6 6.6 0.15 11.9 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) dCache_2 PF08269.11 CBZ35723.1 - 0.21 10.8 0.9 0.68 9.1 0.0 2.0 1 1 1 2 2 2 0 Cache domain Pkinase PF00069.25 CBZ35724.1 - 9.3e-47 159.6 0.0 1.2e-46 159.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35724.1 - 1.5e-26 93.2 0.0 1.9e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ35724.1 - 0.00039 19.8 0.0 0.00056 19.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Cas_Cmr3 PF09700.10 CBZ35724.1 - 0.0054 16.2 0.1 0.0075 15.7 0.1 1.2 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cmr3) Pkinase_fungal PF17667.1 CBZ35724.1 - 0.0098 14.7 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Acetyltransf_1 PF00583.25 CBZ35725.1 - 1.6e-13 50.9 0.0 1.8e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CBZ35725.1 - 1e-10 41.7 0.0 1.3e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CBZ35725.1 - 4.3e-09 36.7 0.0 6.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CBZ35725.1 - 0.00045 20.3 0.0 0.00065 19.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBZ35725.1 - 0.0045 17.1 0.1 0.0067 16.5 0.1 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 CBZ35725.1 - 0.0095 16.6 0.0 0.012 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBZ35725.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 CBZ35725.1 - 0.043 13.8 0.0 0.14 12.2 0.0 1.8 2 1 0 2 2 2 0 ESCO1/2 acetyl-transferase ECH_1 PF00378.20 CBZ35726.1 - 3.8e-38 131.2 0.0 4.5e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ35726.1 - 3.6e-11 43.1 0.0 4.1e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FAD-oxidase_C PF02913.19 CBZ35726.1 - 0.088 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain SPT16 PF08644.11 CBZ35727.1 - 1.4e-30 106.5 1.6 2.1e-30 105.9 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 CBZ35727.1 - 4.1e-14 52.8 0.0 1.2e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CBZ35727.1 - 1.7e-09 38.0 0.0 6.1e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CDC45 PF02724.14 CBZ35727.1 - 1.2 7.4 15.1 2.5 6.3 15.1 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CBZ35727.1 - 3 5.9 15.6 5 5.2 15.6 1.2 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L3 PF00297.22 CBZ35728.1 - 3e-07 29.8 0.1 3e-07 29.8 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L3 PWWP PF00855.17 CBZ35728.1 - 0.1 13.0 0.3 0.23 11.9 0.3 1.6 1 0 0 1 1 1 0 PWWP domain tRNA-synt_1b PF00579.25 CBZ35731.1 - 3.8e-20 72.4 0.0 1.8e-19 70.2 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) ATG11 PF10377.9 CBZ35731.1 - 0.12 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Autophagy-related protein 11 SNARE PF05739.19 CBZ35732.1 - 8.8e-06 25.6 0.9 2.1e-05 24.4 0.9 1.7 1 0 0 1 1 1 1 SNARE domain DUF1664 PF07889.12 CBZ35732.1 - 0.0037 17.3 5.2 0.85 9.7 0.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) Dynactin_p22 PF07426.11 CBZ35732.1 - 0.043 13.7 2.5 0.081 12.8 0.1 2.2 2 0 0 2 2 2 0 Dynactin subunit p22 Syntaxin_2 PF14523.6 CBZ35732.1 - 0.044 14.1 9.4 0.16 12.4 1.5 2.4 2 0 0 2 2 2 0 Syntaxin-like protein RmuC PF02646.16 CBZ35732.1 - 0.12 11.5 7.7 0.035 13.2 1.1 2.7 2 1 1 3 3 3 0 RmuC family LMBR1 PF04791.16 CBZ35732.1 - 0.16 10.8 4.4 0.21 10.5 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Synaptobrevin PF00957.21 CBZ35732.1 - 0.34 10.7 5.5 0.24 11.2 1.9 2.2 2 0 0 2 2 2 0 Synaptobrevin Peroxin-13_N PF04088.13 CBZ35732.1 - 0.44 10.8 3.6 1.7 8.9 0.1 2.8 2 1 1 3 3 3 0 Peroxin 13, N-terminal region BLOC1S3 PF15753.5 CBZ35732.1 - 0.92 9.6 13.4 0.11 12.6 1.0 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Jnk-SapK_ap_N PF09744.9 CBZ35732.1 - 2.6 8.3 15.0 0.4 10.9 6.1 2.5 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 MCU PF04678.13 CBZ35732.1 - 4.9 7.2 7.7 1.7e+02 2.2 7.7 2.2 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Ras PF00071.22 CBZ35734.1 - 1.5e-35 122.2 0.2 1.7e-35 122.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ35734.1 - 1.2e-18 67.5 0.1 1.6e-18 67.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ35734.1 - 2.6e-11 43.3 0.0 3.4e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ35734.1 - 6.5e-06 25.7 0.1 8.5e-06 25.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ35734.1 - 0.0036 17.4 0.0 0.0074 16.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBZ35734.1 - 0.0092 15.7 0.0 0.17 11.6 0.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 CBZ35734.1 - 0.043 13.0 0.0 0.42 9.7 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit tify PF06200.14 CBZ35735.1 - 0.00051 19.3 0.1 0.47 9.8 0.0 2.5 2 0 0 2 2 2 2 tify domain RPN1_RPN2_N PF17781.1 CBZ35737.1 - 2.7e-77 260.2 0.2 7.1e-77 258.8 0.1 1.7 3 0 0 3 3 3 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 CBZ35737.1 - 5.8e-23 80.1 14.9 1.8e-05 24.9 0.0 8.4 9 0 0 9 9 9 5 Proteasome/cyclosome repeat RPN1_C PF18051.1 CBZ35737.1 - 7.4e-19 67.5 0.1 1.5e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 CBZ35737.1 - 0.00075 19.8 4.6 0.18 12.2 0.1 4.7 4 2 1 5 5 5 1 HEAT repeats IFRD PF05004.13 CBZ35737.1 - 0.016 14.3 0.3 0.055 12.6 0.0 2.0 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 CBZ35737.1 - 0.019 15.5 3.3 3.2 8.4 0.1 4.8 5 0 0 5 5 5 0 HEAT-like repeat CHASE6_C PF17150.4 CBZ35737.1 - 0.08 13.6 0.0 3.3 8.5 0.0 3.0 1 1 1 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain PhrC_PhrF PF11131.8 CBZ35737.1 - 0.08 12.5 0.3 0.28 10.8 0.3 1.9 1 0 0 1 1 1 0 Rap-phr extracellular signalling RNA_pol_A_bac PF01000.26 CBZ35739.1 - 1.7e-20 73.4 0.0 3.1e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CBZ35739.1 - 8.9e-17 60.3 0.0 1.3e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fer4_9 PF13187.6 CBZ35739.1 - 0.059 13.5 1.0 0.059 13.5 1.0 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain TPR_19 PF14559.6 CBZ35740.1 - 2.4e-12 47.2 19.8 0.0008 19.9 0.4 6.5 5 1 0 7 7 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ35740.1 - 1.9e-11 44.0 13.8 1.7e-07 31.4 4.0 3.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CBZ35740.1 - 2.1e-11 43.0 23.7 5.7e-05 22.9 0.1 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ35740.1 - 1.3e-09 38.2 19.6 0.0045 17.3 1.0 7.3 6 3 2 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ35740.1 - 2e-07 30.5 22.9 0.019 14.8 0.1 8.0 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ35740.1 - 4.4e-06 26.4 6.2 1.7 8.8 0.1 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ35740.1 - 5.2e-06 26.8 13.2 0.025 15.4 0.0 7.3 6 3 3 9 9 7 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBZ35740.1 - 0.00015 21.4 0.9 0.03 14.0 0.0 4.1 2 1 2 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 CBZ35740.1 - 0.00067 20.3 11.2 0.0023 18.5 0.1 4.9 5 2 1 7 7 5 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CBZ35740.1 - 0.001 19.1 14.8 0.073 13.1 0.3 4.3 3 1 2 5 5 5 3 Putative TPR-like repeat TPR_8 PF13181.6 CBZ35740.1 - 0.0016 18.5 15.5 0.24 11.7 0.1 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_3 PF07720.12 CBZ35740.1 - 0.0067 16.4 0.1 0.0067 16.4 0.1 4.3 4 1 2 6 6 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ35740.1 - 0.009 16.6 0.1 0.009 16.6 0.1 7.3 10 0 0 10 10 7 1 Tetratricopeptide repeat N1221 PF07923.13 CBZ35740.1 - 0.0095 15.2 1.2 0.015 14.5 0.1 1.9 2 0 0 2 2 2 1 N1221-like protein tRNA-synt_His PF13393.6 CBZ35740.1 - 0.07 12.4 1.3 2.4 7.4 0.0 2.8 3 0 0 3 3 3 0 Histidyl-tRNA synthetase PPR PF01535.20 CBZ35740.1 - 0.087 13.1 11.0 15 6.1 0.1 5.1 6 0 0 6 6 4 0 PPR repeat Sec16_C PF12931.7 CBZ35740.1 - 0.14 11.7 3.3 0.62 9.7 0.4 2.5 3 0 0 3 3 3 0 Sec23-binding domain of Sec16 TPR_9 PF13371.6 CBZ35740.1 - 0.28 11.4 2.1 28 5.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ35740.1 - 0.4 11.2 6.2 27 5.4 0.3 5.1 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF3829 PF12889.7 CBZ35740.1 - 1.4 8.3 10.4 4.8 6.6 0.4 3.5 2 2 0 2 2 2 0 Protein of unknown function (DUF3829) Fis1_TPR_C PF14853.6 CBZ35740.1 - 1.9 8.7 17.9 10 6.3 0.3 5.5 3 1 2 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CBZ35740.1 - 2 8.4 8.9 21 5.1 0.2 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 CBZ35740.1 - 4.6 7.6 10.3 17 5.8 0.1 4.4 5 1 0 5 5 4 0 Tetratricopeptide repeat UPF0182 PF03699.13 CBZ35741.1 - 0.24 9.5 2.0 0.62 8.1 2.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) IPP-2 PF04979.14 CBZ35742.1 - 1.6e-22 80.6 2.5 1.9e-22 80.4 2.5 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) zf-RanBP PF00641.18 CBZ35743.1 - 0.012 14.9 7.7 0.012 14.9 7.7 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DivIVA PF05103.13 CBZ35744.1 - 8.7 6.4 12.2 4.2 7.5 9.1 2.1 2 0 0 2 2 2 0 DivIVA protein SNF2_N PF00176.23 CBZ35745.1 - 1.4e-30 106.2 0.0 2.4e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ35745.1 - 5.5e-11 42.8 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ35745.1 - 2.8e-07 30.7 0.0 4.2e-06 26.9 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CBZ35745.1 - 0.00044 20.0 0.1 0.0031 17.2 0.0 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase ERCC3_RAD25_C PF16203.5 CBZ35745.1 - 0.0016 17.7 0.0 0.0028 16.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CBZ35745.1 - 0.063 13.5 0.2 0.32 11.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain TruB_C_2 PF16198.5 CBZ35745.1 - 0.26 11.4 2.2 0.59 10.3 1.0 2.4 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain Remorin_C PF03763.13 CBZ35746.1 - 0.0055 16.6 2.8 0.0055 16.6 2.8 1.6 2 0 0 2 2 2 1 Remorin, C-terminal region DUF2207 PF09972.9 CBZ35746.1 - 0.02 13.7 0.1 0.026 13.3 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Chi-conotoxin PF16981.5 CBZ35746.1 - 0.41 10.9 0.0 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 chi-Conotoxin or t superfamily Sec23_trunk PF04811.15 CBZ35747.1 - 6.6e-42 143.7 0.0 1.1e-41 143.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CBZ35747.1 - 6e-21 75.0 0.0 1.6e-20 73.6 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CBZ35747.1 - 1.8e-13 50.3 2.3 3.8e-13 49.2 2.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 CBZ35747.1 - 1.2e-10 41.1 0.0 2.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Maf_N PF08383.11 CBZ35747.1 - 0.024 14.4 0.1 2 8.3 0.0 2.8 2 0 0 2 2 2 0 Maf N-terminal region DNA_RNApol_7kD PF03604.13 CBZ35747.1 - 0.066 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit DUF4893 PF16233.5 CBZ35747.1 - 0.17 11.4 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4893) RIO1 PF01163.22 CBZ35749.1 - 2.2e-65 219.8 0.3 7.2e-65 218.1 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 CBZ35749.1 - 0.087 11.6 0.0 0.087 11.6 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 CBZ35749.1 - 0.093 12.6 0.1 0.66 9.9 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family CDC45 PF02724.14 CBZ35749.1 - 0.42 8.8 6.0 0.58 8.4 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DIOX_N PF14226.6 CBZ35750.1 - 1.2e-35 122.8 0.0 1.9e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CBZ35750.1 - 3e-24 85.4 0.0 6.2e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TTL PF03133.15 CBZ35751.1 - 8.8e-42 143.2 0.0 8.3e-19 67.8 0.0 3.2 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 CBZ35751.1 - 0.0039 16.5 0.0 2.8 7.1 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp FAD-oxidase_C PF02913.19 CBZ35753.1 - 5.5e-46 157.2 0.2 9.2e-46 156.5 0.2 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBZ35753.1 - 5.5e-38 129.9 0.5 1.1e-37 128.8 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain zf-C2HC_2 PF13913.6 CBZ35754.1 - 1.4e-18 66.3 8.6 5.4e-11 42.1 1.5 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 CBZ35754.1 - 0.00032 21.3 4.5 0.086 13.7 0.5 2.9 3 0 0 3 3 2 2 C2H2-type zinc finger zf-RING_7 PF02591.15 CBZ35754.1 - 0.0076 16.4 3.2 2.5 8.4 0.1 2.9 3 0 0 3 3 2 2 C4-type zinc ribbon domain zinc_ribbon_9 PF14369.6 CBZ35754.1 - 0.011 16.0 3.0 4 7.8 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon zf-FPG_IleRS PF06827.14 CBZ35754.1 - 0.013 15.4 9.2 0.29 11.1 2.5 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.10 CBZ35754.1 - 0.013 15.6 3.0 2.4 8.3 0.6 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.26 CBZ35754.1 - 0.031 14.7 6.0 0.28 11.7 1.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf_UBZ PF18439.1 CBZ35754.1 - 0.047 13.3 1.7 7.3 6.3 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger RNF220 PF15926.5 CBZ35754.1 - 0.055 13.1 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase RNF220 zf-Di19 PF05605.12 CBZ35754.1 - 0.16 12.3 9.8 0.24 11.7 1.1 2.6 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 CBZ35754.1 - 0.17 11.3 4.6 3.1 7.3 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain NinG PF05766.12 CBZ35754.1 - 0.24 11.3 0.8 17 5.3 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein Lar_restr_allev PF14354.6 CBZ35754.1 - 0.42 11.0 4.7 0.87 10.0 0.4 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar ADK_lid PF05191.14 CBZ35754.1 - 0.44 10.6 4.9 7.1 6.7 0.3 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid Rad50_zn_hook PF04423.14 CBZ35754.1 - 0.44 10.4 2.9 13 5.7 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_1 PF14446.6 CBZ35754.1 - 0.56 10.2 2.4 6.3 6.8 0.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Nairovirus_M PF07948.11 CBZ35754.1 - 0.58 8.3 1.5 2.3 6.3 0.1 1.9 2 0 0 2 2 2 0 Nairovirus M polyprotein-like Zn_Tnp_IS1595 PF12760.7 CBZ35754.1 - 1.4 8.9 4.9 8.5 6.4 1.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2256 PF10013.9 CBZ35754.1 - 1.8 8.7 5.8 14 5.9 0.1 3.0 3 0 0 3 3 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Sgf11 PF08209.11 CBZ35754.1 - 2.2 7.9 5.5 12 5.5 0.8 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zinc_ribbon_2 PF13240.6 CBZ35754.1 - 3.6 7.4 9.5 3.3 7.6 0.1 2.7 3 0 0 3 3 2 0 zinc-ribbon domain YacG PF03884.14 CBZ35754.1 - 3.8 7.3 5.8 1.9 8.3 0.5 2.4 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG Prim_Zn_Ribbon PF08273.12 CBZ35754.1 - 9.8 6.6 7.2 20 5.6 0.7 2.7 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase FHA PF00498.26 CBZ35755.1 - 1.4e-07 31.8 0.0 1.3e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CBZ35755.1 - 0.011 16.0 0.0 5.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain STI1 PF17830.1 CBZ35757.1 - 7.2e-13 48.3 14.5 7.2e-13 48.3 14.5 1.9 2 0 0 2 2 2 1 STI1 domain TPR_2 PF07719.17 CBZ35757.1 - 5.1e-09 35.6 3.2 0.02 15.0 0.7 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ35757.1 - 7e-07 29.3 0.5 2.5e-06 27.5 0.4 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ35757.1 - 1.1e-05 25.0 0.6 0.0056 16.5 0.5 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ35757.1 - 1.3e-05 24.8 0.1 0.14 11.8 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 CBZ35757.1 - 1.5e-05 25.0 0.3 0.24 11.9 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ35757.1 - 0.0099 16.0 0.2 1.9 8.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Rrn6 PF10214.9 CBZ35757.1 - 0.093 11.2 0.2 0.11 11.0 0.2 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF2999 PF11212.8 CBZ35757.1 - 0.13 12.6 4.7 27 5.1 4.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2999) NARP1 PF12569.8 CBZ35757.1 - 0.21 10.5 9.3 0.16 10.9 7.2 1.7 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 ArfGap PF01412.18 CBZ35758.1 - 4.8e-39 133.1 0.1 9.1e-39 132.2 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf FGF-BP1 PF06473.12 CBZ35758.1 - 1.4 8.7 7.1 2.3 8.0 7.1 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) UBA_4 PF14555.6 CBZ35759.1 - 1e-06 28.5 0.2 2.2e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 CBZ35759.1 - 0.00031 20.9 0.3 0.0009 19.4 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin-like HipA_C PF07804.12 CBZ35760.1 - 0.026 14.2 1.1 0.49 10.1 0.8 2.9 2 0 0 2 2 2 0 HipA-like C-terminal domain zf-met PF12874.7 CBZ35761.1 - 0.0042 17.4 0.4 0.0085 16.5 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AKAP95 PF04988.12 CBZ35761.1 - 0.039 14.2 0.1 0.064 13.5 0.1 1.2 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Pkinase PF00069.25 CBZ35762.1 - 1.6e-42 145.7 0.0 4.2e-20 72.2 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35762.1 - 2.6e-23 82.6 0.1 1.5e-14 53.9 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ35762.1 - 0.00054 19.4 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CBZ35762.1 - 0.007 16.3 0.5 0.057 13.3 0.2 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CBZ35762.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 CBZ35762.1 - 0.26 10.6 0.1 0.51 9.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C2-C2_1 PF11618.8 CBZ35763.1 - 2.8e-06 27.5 0.0 2.8e-06 27.5 0.0 3.7 4 1 1 5 5 5 1 First C2 domain of RPGR-interacting protein 1 Cep57_CLD PF14073.6 CBZ35763.1 - 0.0011 19.1 1.4 0.0011 19.1 1.4 5.1 3 1 2 5 5 5 1 Centrosome localisation domain of Cep57 RRM_1 PF00076.22 CBZ35764.1 - 9.1e-15 54.2 0.1 1.1e-06 28.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ35764.1 - 0.075 13.0 0.2 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_pol_Rpb4 PF03874.16 CBZ35765.1 - 8.9e-05 22.8 0.0 0.00019 21.7 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb4 Prolamin_like PF05617.11 CBZ35765.1 - 0.078 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Prolamin-like zf-CCCH PF00642.24 CBZ35767.1 - 0.0081 16.1 0.4 0.012 15.5 0.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBZ35767.1 - 0.021 15.5 0.0 0.04 14.6 0.0 1.4 1 0 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 CBZ35767.1 - 1.1 9.4 5.7 1.6 8.9 5.7 1.3 1 0 0 1 1 1 0 Zinc finger domain PPR_3 PF13812.6 CBZ35768.1 - 0.0012 18.9 0.0 0.0063 16.6 0.0 2.1 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 CBZ35768.1 - 0.019 15.1 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 PPR repeat family DUF2890 PF11081.8 CBZ35768.1 - 0.038 14.1 1.2 0.072 13.2 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) HycH PF07450.11 CBZ35768.1 - 0.057 13.8 0.0 2.4 8.5 0.0 3.0 3 0 0 3 3 3 0 Formate hydrogenlyase maturation protein HycH PPR PF01535.20 CBZ35768.1 - 0.08 13.2 0.0 29 5.2 0.0 3.6 3 0 0 3 3 3 0 PPR repeat PPR_1 PF12854.7 CBZ35768.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 PPR repeat Metallophos PF00149.28 CBZ35769.1 - 3.1e-06 27.8 0.0 4.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rad51 PF08423.11 CBZ35770.1 - 1.9e-22 79.8 0.3 4.2e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 Rad51 RecA PF00154.21 CBZ35770.1 - 2.1e-09 37.3 1.2 6.9e-07 29.0 0.1 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 CBZ35770.1 - 2e-07 30.6 0.0 4.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 KaiC CASP_C PF08172.12 CBZ35771.1 - 0.006 16.0 3.6 0.006 16.0 3.6 3.5 3 1 0 3 3 3 1 CASP C terminal Tox-ODYAM1 PF15642.6 CBZ35771.1 - 0.35 9.8 3.2 0.71 8.8 3.2 1.5 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus AAA_23 PF13476.6 CBZ35771.1 - 1.5 9.3 6.4 3.4 8.1 1.5 2.4 2 0 0 2 2 2 0 AAA domain DGF-1_C PF11040.8 CBZ35771.1 - 2.6 8.1 9.6 4.1 7.5 3.2 3.0 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Gly-zipper_Omp PF13488.6 CBZ35772.1 - 0.009 16.0 8.9 0.009 16.0 8.9 2.5 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_OmpA PF13436.6 CBZ35772.1 - 1.2 9.0 16.8 0.56 10.0 12.9 2.5 2 0 0 2 2 2 0 Glycine-zipper domain CaATP_NAI PF12515.8 CBZ35775.1 - 8.5e-19 66.9 0.3 2.1e-18 65.6 0.3 1.8 1 0 0 1 1 1 1 Ca2+-ATPase N terminal autoinhibitory domain OrsD PF12013.8 CBZ35775.1 - 0.2 12.1 1.0 1.2 9.6 0.4 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Cofilin_ADF PF00241.20 CBZ35776.1 - 1.3e-29 102.4 0.1 1.5e-29 102.2 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RNase_T PF00929.24 CBZ35779.1 - 8.2e-27 94.8 0.0 2.9e-25 89.7 0.0 2.2 1 1 0 1 1 1 1 Exonuclease Ndc1_Nup PF09531.10 CBZ35779.1 - 1.4 7.5 2.5 2 7.0 2.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RNase_T PF00929.24 CBZ35780.1 - 2.3e-27 96.6 0.0 3.2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 CBZ35780.1 - 0.058 13.4 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like PSRT PF07636.11 CBZ35780.1 - 0.059 13.1 5.3 0.081 12.6 1.9 2.9 2 0 0 2 2 2 0 PSRT RNase_T PF00929.24 CBZ35782.1 - 1.5e-25 90.7 0.0 2.4e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 CBZ35782.1 - 0.033 14.2 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like Ank_2 PF12796.7 CBZ35783.1 - 1.7e-15 57.4 0.6 2.2e-07 31.4 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ35783.1 - 4.9e-08 33.4 0.3 0.0035 17.9 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ35783.1 - 1.9e-06 28.0 1.0 0.17 12.4 0.1 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CBZ35783.1 - 3e-05 24.1 0.4 2.5 8.9 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CBZ35783.1 - 0.00022 21.5 2.2 0.098 13.0 0.3 3.7 3 1 0 3 3 3 2 Ankyrin repeats (many copies) ERCC3_RAD25_C PF16203.5 CBZ35785.1 - 3.7e-62 209.7 0.0 9.2e-55 185.5 0.0 2.3 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CBZ35785.1 - 3e-14 53.4 0.0 4.6e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ35785.1 - 5.9e-10 39.5 0.0 1.9e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_3 PF13625.6 CBZ35785.1 - 3.1e-07 30.6 0.1 1e-06 28.9 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ35785.1 - 0.0068 16.2 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-NF-X1 PF01422.17 CBZ35786.1 - 1.8e-07 31.1 37.3 1e-05 25.5 14.1 15.0 16 0 0 16 16 16 6 NF-X1 type zinc finger zf-CCHC_2 PF13696.6 CBZ35787.1 - 1.1e-09 37.9 3.5 2.1e-09 37.0 3.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_jaz PF12171.8 CBZ35787.1 - 6.6e-05 23.1 0.2 0.00033 20.9 0.5 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CBZ35787.1 - 0.0016 18.8 2.2 0.031 14.7 0.1 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type eIF3g PF12353.8 CBZ35787.1 - 0.011 16.1 0.0 0.011 16.1 0.0 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_5 PF14787.6 CBZ35787.1 - 0.015 15.0 1.3 0.015 15.0 1.3 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger NUFIP1 PF10453.9 CBZ35787.1 - 0.021 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-LITAF-like PF10601.9 CBZ35787.1 - 0.04 14.2 0.3 0.04 14.2 0.3 1.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-C2H2_4 PF13894.6 CBZ35787.1 - 0.092 13.6 0.2 0.092 13.6 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CBZ35787.1 - 0.2 12.1 0.3 0.49 10.9 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ABC2_membrane_3 PF12698.7 CBZ35788.1 - 2.8e-62 210.9 62.6 9.5e-46 156.5 25.7 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 CBZ35788.1 - 1.9e-54 183.9 0.0 3.2e-27 95.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ35788.1 - 2.4e-11 44.0 6.0 0.0018 18.2 0.0 4.5 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ35788.1 - 2e-09 37.2 0.0 0.0002 20.9 0.2 3.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ35788.1 - 5.7e-05 22.8 1.3 0.0064 16.2 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CBZ35788.1 - 0.00049 19.9 1.3 0.083 12.6 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CBZ35788.1 - 0.00087 19.8 0.4 0.22 12.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBZ35788.1 - 0.0029 17.5 0.3 0.91 9.4 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase RNA_helicase PF00910.22 CBZ35788.1 - 0.03 14.7 0.3 5.5 7.4 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_25 PF13481.6 CBZ35788.1 - 0.071 12.7 3.9 2.2 7.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 CBZ35788.1 - 0.12 11.9 0.4 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 CBZ35788.1 - 0.75 9.4 4.0 1.6 8.3 0.4 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2207 PF09972.9 CBZ35790.1 - 0.0034 16.2 0.0 0.004 16.0 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) PET117 PF15786.5 CBZ35790.1 - 0.008 16.4 0.2 0.016 15.5 0.2 1.5 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF919 PF06034.11 CBZ35790.1 - 0.069 13.0 0.4 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DcpS_C PF11969.8 CBZ35791.1 - 1.1e-23 83.9 0.6 2.8e-23 82.6 0.3 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CBZ35791.1 - 2.1e-13 50.8 0.7 7.3e-13 49.1 0.2 2.0 3 0 0 3 3 3 1 HIT domain zf-C2HE PF16278.5 CBZ35791.1 - 2.8e-07 30.9 0.0 5.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 CBZ35791.1 - 0.049 14.0 0.2 0.098 13.0 0.2 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) PHO4 PF01384.20 CBZ35792.1 - 3.7e-85 286.0 14.9 4.4e-85 285.7 14.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF436 PF04260.12 CBZ35792.1 - 0.027 14.1 0.2 0.075 12.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF436) RRM_1 PF00076.22 CBZ35795.1 - 1.2e-22 79.5 0.0 9.7e-14 50.9 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RHD3 PF05879.12 CBZ35796.1 - 0.017 13.3 0.0 0.021 13.0 0.0 1.0 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) CLAMP PF14769.6 CBZ35797.1 - 0.046 14.2 0.0 3.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 Ribosomal_L37 PF08561.10 CBZ35797.1 - 3.1 8.3 5.5 16 6.0 0.3 3.2 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L37 BBS2_Mid PF14783.6 CBZ35798.1 - 0.0043 17.1 0.2 2.2 8.4 0.1 2.7 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 CBZ35798.1 - 0.0043 17.1 2.5 0.012 15.8 2.5 1.7 1 0 0 1 1 1 1 FG-GAP repeat Itfg2 PF15907.5 CBZ35798.1 - 0.018 14.1 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 VCBS PF13517.6 CBZ35798.1 - 0.02 15.4 0.2 0.072 13.7 0.2 1.9 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF_TS PF00889.19 CBZ35799.1 - 3.5e-14 52.9 0.0 9.4e-14 51.5 0.0 1.6 1 1 1 2 2 2 1 Elongation factor TS HOIP-UBA PF16678.5 CBZ35799.1 - 0.15 12.1 0.2 2.2 8.3 0.0 2.6 3 1 0 3 3 3 0 HOIP UBA domain pair SAF PF08666.12 CBZ35799.1 - 0.15 12.7 0.0 6.2 7.5 0.0 2.3 2 0 0 2 2 2 0 SAF domain UPF0175 PF03683.13 CBZ35800.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) WD40 PF00400.32 CBZ35801.1 - 3.9e-20 71.8 7.3 0.00023 21.9 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Mpp10 PF04006.12 CBZ35802.1 - 9.2e-67 225.9 26.4 1.3e-66 225.3 26.4 1.1 1 0 0 1 1 1 1 Mpp10 protein HSP90 PF00183.18 CBZ35803.1 - 2.3e-173 577.8 9.0 2.9e-173 577.5 9.0 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 CBZ35803.1 - 6.1e-08 32.6 0.0 1.7e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBZ35803.1 - 2.2e-06 28.2 0.0 8.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GSH-S_ATP PF02955.16 CBZ35803.1 - 0.052 13.0 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, ATP-grasp domain Plasmid_RAQPRD PF09686.10 CBZ35804.1 - 0.048 13.9 5.8 0.74 10.1 0.1 2.6 2 1 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) U-box PF04564.15 CBZ35805.1 - 1.6e-12 47.4 0.0 1.1e-11 44.7 0.0 2.4 3 0 0 3 3 3 1 U-box domain zf-Nse PF11789.8 CBZ35805.1 - 0.00014 21.6 0.0 0.00035 20.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 CBZ35805.1 - 0.17 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein YqfQ PF14181.6 CBZ35809.1 - 5.8 7.1 6.3 15 5.8 0.4 2.7 2 0 0 2 2 2 0 YqfQ-like protein Peptidase_C1 PF00112.23 CBZ35810.1 - 4.6e-60 203.4 4.2 5.5e-60 203.2 4.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 CBZ35810.1 - 0.00031 19.7 2.6 0.0037 16.1 0.5 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Propeptide_C1 PF08127.13 CBZ35810.1 - 0.00061 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family C1 propeptide Nop14 PF04147.12 CBZ35811.1 - 3 5.9 5.5 3.8 5.6 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 CBZ35811.1 - 9.4 5.4 11.8 14 4.9 11.8 1.2 1 0 0 1 1 1 0 BUD22 DUF1634 PF07843.11 CBZ35812.1 - 0.085 12.9 3.6 3.3 7.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) HMG_box PF00505.19 CBZ35813.1 - 8.8e-34 115.8 11.5 5.4e-21 74.8 1.5 3.0 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CBZ35813.1 - 1.2e-19 70.7 21.5 4.5e-12 46.4 1.1 3.2 3 1 0 3 3 3 2 HMG-box domain Protamine_like PF06382.11 CBZ35813.1 - 1.4e-07 31.8 13.7 7.5e-05 22.9 2.7 2.2 1 1 1 2 2 2 2 Protamine and protamine like DEK_C PF08766.11 CBZ35813.1 - 1.5e-05 24.8 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain HMG_box_5 PF14887.6 CBZ35813.1 - 8.4e-05 22.5 16.5 0.0006 19.7 1.3 3.1 3 0 0 3 3 3 2 HMG (high mobility group) box 5 DUF1088 PF06469.11 CBZ35813.1 - 0.14 11.8 3.5 0.16 11.6 1.7 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1088) COX4 PF02936.14 CBZ35813.1 - 0.52 10.3 5.7 3.6 7.6 0.2 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV YABBY PF04690.13 CBZ35813.1 - 2.5 8.6 10.7 0.11 13.0 3.5 2.1 1 1 1 2 2 2 0 YABBY protein Cyt-b5 PF00173.28 CBZ35814.1 - 7.1e-09 35.7 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.22 CBZ35816.1 - 4.9e-07 29.5 0.0 7.8e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ35816.1 - 0.014 15.0 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ35816.1 - 0.077 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Amidohydro_1 PF01979.20 CBZ35817.1 - 6.4e-55 186.8 0.0 1e-54 186.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CBZ35817.1 - 2.9e-09 36.9 0.0 7.8e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF4202 PF13875.6 CBZ35818.1 - 0.0093 15.9 0.1 0.0093 15.9 0.1 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4202) TPR_8 PF13181.6 CBZ35818.1 - 0.13 12.5 1.0 11 6.5 0.1 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Arf PF00025.21 CBZ35819.1 - 1.3e-64 216.9 0.0 1.4e-64 216.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBZ35819.1 - 3.6e-15 55.9 0.0 4.4e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CBZ35819.1 - 9.2e-15 54.9 0.0 1.2e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ35819.1 - 1.7e-14 53.7 0.0 1.9e-14 53.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBZ35819.1 - 5.5e-12 45.5 0.2 3.8e-09 36.2 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBZ35819.1 - 4.3e-11 42.6 0.0 5.1e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ35819.1 - 4.1e-08 33.3 0.0 5.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ35819.1 - 0.00052 19.6 0.0 0.0018 17.9 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CBZ35819.1 - 0.0021 17.5 0.0 0.0035 16.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein cobW PF02492.19 CBZ35819.1 - 0.0047 16.5 0.0 0.059 12.9 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBZ35819.1 - 0.014 15.4 0.0 3.5 7.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CBZ35819.1 - 0.072 13.5 0.3 0.28 11.5 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 CBZ35819.1 - 0.097 11.6 0.1 0.48 9.4 0.1 1.9 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PhyH PF05721.13 CBZ35820.1 - 2.4e-06 28.0 0.0 7.8e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) C1_1 PF00130.22 CBZ35820.1 - 9.8e-05 22.2 4.9 0.00029 20.6 4.9 1.8 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 CBZ35820.1 - 0.037 13.9 9.7 0.092 12.7 9.7 1.8 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 CBZ35820.1 - 0.045 13.7 9.4 0.12 12.3 9.4 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 CBZ35820.1 - 0.39 10.8 8.0 0.87 9.7 8.0 1.6 1 0 0 1 1 1 0 PHD-finger OrfB_Zn_ribbon PF07282.11 CBZ35820.1 - 1.4 8.9 11.2 0.39 10.7 4.3 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-PARP PF00645.18 CBZ35820.1 - 5.2 8.0 6.9 12 6.8 6.9 1.7 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DZR PF12773.7 CBZ35820.1 - 5.8 7.0 9.8 32 4.6 9.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon SLC35F PF06027.12 CBZ35821.1 - 9.2e-62 209.2 26.5 3.2e-47 161.5 6.1 2.0 2 0 0 2 2 2 2 Solute carrier family 35 CRT-like PF08627.10 CBZ35821.1 - 4.6e-12 45.5 6.7 4.6e-12 45.5 6.7 1.8 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CBZ35821.1 - 8.8e-09 35.7 41.9 0.00018 21.7 13.8 3.0 3 0 0 3 3 3 2 EamA-like transporter family IPPT PF01715.17 CBZ35822.1 - 6.3e-15 55.6 0.0 9.4e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 CBZ35822.1 - 5.4e-06 26.6 0.5 9.3e-06 25.9 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CBZ35822.1 - 0.027 14.8 0.3 0.047 14.0 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Peptidase_A22B PF04258.13 CBZ35823.1 - 1.5e-62 211.7 18.7 3.3e-57 194.2 9.9 2.0 1 1 1 2 2 2 2 Signal peptide peptidase SPP PF06550.11 CBZ35823.1 - 0.0059 16.1 13.8 0.025 14.0 13.8 1.9 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease DUF2157 PF09925.9 CBZ35823.1 - 1.3 8.8 10.1 12 5.7 10.1 2.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) LETM1 PF07766.13 CBZ35824.1 - 5.9e-62 209.4 0.0 2.8e-61 207.2 0.0 1.9 2 0 0 2 2 2 1 LETM1-like protein DASH_Duo1 PF08651.10 CBZ35824.1 - 0.061 13.1 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 ABC2_membrane PF01061.24 CBZ35825.1 - 0.0018 17.7 18.5 0.0035 16.8 18.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CBZ35825.1 - 0.058 13.9 0.0 0.091 13.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter FGE-sulfatase PF03781.16 CBZ35827.1 - 3.6e-21 75.9 1.3 7.7e-21 74.8 1.3 1.6 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 CBZ35827.1 - 2e-05 25.1 0.0 4.8e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.6 CBZ35827.1 - 6e-05 23.7 0.1 0.0047 17.6 0.1 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ35827.1 - 0.002 18.0 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ35827.1 - 0.0021 17.9 0.0 0.0059 16.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ35827.1 - 0.052 14.2 0.1 0.2 12.3 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ35827.1 - 0.079 13.7 0.0 0.24 12.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF2938 PF11158.8 CBZ35828.1 - 0.027 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2938) DUF4761 PF15958.5 CBZ35829.1 - 0.0085 16.2 0.2 0.046 13.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4761) Kinesin PF00225.23 CBZ35830.1 - 8.9e-84 281.3 0.1 1.4e-82 277.4 0.0 2.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ35830.1 - 1.9e-15 57.1 0.9 1.3e-14 54.4 0.0 3.0 3 0 0 3 3 3 1 Microtubule binding HTH_16 PF12645.7 CBZ35830.1 - 0.029 14.4 0.1 0.22 11.6 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain UL41A PF17591.2 CBZ35831.1 - 0.2 11.8 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus UL41A Baculo_PEP_C PF04513.12 CBZ35833.1 - 1.4e-05 25.1 4.3 0.15 12.1 0.0 3.3 3 1 1 4 4 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 CBZ35833.1 - 0.0013 17.7 19.6 0.0034 16.3 2.4 3.2 3 0 0 3 3 3 2 Spc7 kinetochore protein EzrA PF06160.12 CBZ35833.1 - 0.0013 17.0 0.7 0.027 12.7 0.6 2.4 2 0 0 2 2 2 1 Septation ring formation regulator, EzrA COG5 PF10392.9 CBZ35833.1 - 0.015 15.4 0.3 0.015 15.4 0.3 3.1 3 1 0 3 3 3 0 Golgi transport complex subunit 5 KASH_CCD PF14662.6 CBZ35833.1 - 0.019 14.8 0.3 0.019 14.8 0.3 3.3 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH LcrV PF04792.12 CBZ35833.1 - 0.05 12.9 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 V antigen (LcrV) protein Mto2_bdg PF12808.7 CBZ35833.1 - 0.054 13.8 8.0 0.11 12.9 0.4 3.4 3 0 0 3 3 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region YabA PF06156.13 CBZ35833.1 - 0.059 14.0 0.4 0.059 14.0 0.4 4.3 4 2 1 5 5 5 0 Initiation control protein YabA DUF1515 PF07439.11 CBZ35833.1 - 0.07 13.2 0.3 0.07 13.2 0.3 4.2 4 1 1 5 5 4 0 Protein of unknown function (DUF1515) BLOC1_2 PF10046.9 CBZ35833.1 - 0.078 13.3 6.9 7.8 6.9 0.1 4.1 4 1 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TIP120 PF08623.10 CBZ35833.1 - 0.082 12.7 0.7 9 6.0 0.4 2.4 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) TMF_TATA_bd PF12325.8 CBZ35833.1 - 0.12 12.6 16.0 0.23 11.7 0.3 3.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.15 CBZ35833.1 - 0.14 12.2 0.3 0.14 12.2 0.3 5.2 7 0 0 7 7 5 0 Basic region leucine zipper FlaC_arch PF05377.11 CBZ35833.1 - 0.16 12.4 0.7 42 4.6 0.0 3.9 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) DUF4611 PF15387.6 CBZ35833.1 - 0.18 12.0 1.5 1.7 8.9 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TraF_2 PF13729.6 CBZ35833.1 - 0.2 11.0 1.4 0.88 8.9 0.3 2.2 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein ZapB PF06005.12 CBZ35833.1 - 0.21 12.0 21.4 1.5 9.4 2.1 4.6 3 1 0 3 3 3 0 Cell division protein ZapB DUF4795 PF16043.5 CBZ35833.1 - 0.24 11.0 12.4 0.043 13.4 2.1 3.6 3 2 0 3 3 3 0 Domain of unknown function (DUF4795) Fib_alpha PF08702.10 CBZ35833.1 - 0.29 11.3 11.8 0.5 10.5 0.3 4.5 3 2 1 5 5 5 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 CBZ35833.1 - 1.5 9.3 8.2 4.2 7.9 0.4 3.9 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Jnk-SapK_ap_N PF09744.9 CBZ35833.1 - 1.8 8.8 19.5 0.21 11.8 1.4 3.6 3 1 0 3 3 3 0 JNK_SAPK-associated protein-1 HALZ PF02183.18 CBZ35833.1 - 2.4 8.5 6.2 0.35 11.1 0.2 2.8 3 0 0 3 3 2 0 Homeobox associated leucine zipper Cnn_1N PF07989.11 CBZ35833.1 - 7.3 6.8 12.4 4.3 7.6 0.3 3.9 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 DUF501 PF04417.12 CBZ35833.1 - 7.8 6.3 8.9 1.3 8.9 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Snapin_Pallidin PF14712.6 CBZ35833.1 - 7.9 7.0 15.2 4 7.9 0.1 4.4 3 2 1 4 4 4 0 Snapin/Pallidin CREPT PF16566.5 CBZ35833.1 - 9 6.5 16.3 7.7 6.7 1.9 4.0 3 2 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour ADH_zinc_N_2 PF13602.6 CBZ35834.1 - 2.3e-15 57.8 0.0 6.5e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ35834.1 - 1e-11 44.7 0.3 1.3e-10 41.2 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBZ35834.1 - 1.1e-08 35.1 0.0 6.4e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase SseB PF07179.12 CBZ35835.1 - 0.00071 19.8 0.0 1.5 9.1 0.0 2.8 2 0 0 2 2 2 2 SseB protein N-terminal domain Band_3_cyto PF07565.13 CBZ35836.1 - 0.45 10.3 7.2 0.59 9.9 7.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Nexin_C PF08628.12 CBZ35836.1 - 2.7 8.6 9.7 11 6.6 7.3 2.8 2 1 0 2 2 2 0 Sorting nexin C terminal DUF1043 PF06295.12 CBZ35836.1 - 3.8 7.5 7.7 27 4.8 7.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) cNMP_binding PF00027.29 CBZ35837.1 - 1.1e-15 57.5 0.0 3.9e-08 33.3 0.0 4.5 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Ku PF02735.16 CBZ35838.1 - 2.1e-26 92.9 0.0 4.7e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CBZ35838.1 - 4e-17 62.7 0.0 5.4e-10 39.4 0.0 2.6 3 0 0 3 3 3 2 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CBZ35838.1 - 4.8e-05 24.0 0.3 0.0011 19.6 0.3 2.5 1 1 0 1 1 1 1 Ku70/Ku80 C-terminal arm HeH PF12949.7 CBZ35838.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain SAP PF02037.27 CBZ35838.1 - 0.17 11.7 0.0 0.41 10.5 0.0 1.6 1 0 0 1 1 1 0 SAP domain Ribosomal_L4 PF00573.22 CBZ35840.1 - 5.5e-10 39.2 0.1 6.2e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L4 PF00573.22 CBZ35841.1 - 7.7e-36 123.6 0.1 1.3e-35 122.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CBZ35841.1 - 6.8e-20 70.9 5.4 1e-19 70.4 2.5 2.4 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Ribosomal_L4 PF00573.22 CBZ35842.1 - 1.4e-10 41.2 0.2 1.6e-10 41.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ank_2 PF12796.7 CBZ35843.1 - 5.2e-32 110.3 0.0 4.7e-11 43.1 0.0 3.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ35843.1 - 1.9e-24 85.7 0.1 2.1e-10 40.9 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ35843.1 - 2.5e-20 70.4 0.0 0.023 15.2 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CBZ35843.1 - 4.5e-16 58.5 0.0 0.00036 20.8 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CBZ35843.1 - 4.7e-14 52.3 0.4 4.9e-06 26.7 0.0 5.7 3 3 2 5 5 5 4 Ankyrin repeats (many copies) PSP1 PF04468.12 CBZ35845.1 - 5.5e-13 49.0 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Thioredoxin_8 PF13905.6 CBZ35846.1 - 4.1e-11 43.1 0.0 7.6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CBZ35846.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ35846.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 CBZ35847.1 - 2.3e-20 72.7 0.0 6.1e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CBZ35847.1 - 4.4e-12 46.0 0.0 7.3e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ35847.1 - 5.6e-12 45.6 0.0 1.6e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Redoxin Thioredoxin PF00085.20 CBZ35847.1 - 2.7e-07 30.5 0.0 6.4e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 CBZ35847.1 - 1.2e-05 25.2 0.0 3e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CBZ35847.1 - 0.00021 21.4 0.0 0.00046 20.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBZ35847.1 - 0.00044 20.7 0.1 0.0024 18.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CBZ35847.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin DUF4234 PF14018.6 CBZ35847.1 - 0.032 14.3 1.6 0.058 13.5 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Hex_IIIa PF02455.16 CBZ35847.1 - 0.21 10.3 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Thioredoxin_8 PF13905.6 CBZ35848.1 - 1.2e-23 83.3 0.0 1.5e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CBZ35848.1 - 1.7e-06 27.9 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 CBZ35848.1 - 1.8e-06 27.8 0.2 1.6e-05 24.8 0.1 1.9 1 1 1 2 2 2 1 Thioredoxin Redoxin PF08534.10 CBZ35848.1 - 2.6e-06 27.2 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 CBZ35848.1 - 2.4e-05 24.3 0.0 0.0001 22.2 0.0 1.8 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 CBZ35848.1 - 0.0011 19.4 0.1 0.0019 18.6 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBZ35848.1 - 0.02 15.1 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DUF953 PF06110.11 CBZ35848.1 - 0.032 13.8 0.0 7.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_8 PF13905.6 CBZ35849.1 - 4.4e-26 91.0 0.0 6.3e-26 90.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 CBZ35849.1 - 7e-09 35.6 0.1 3.1e-06 27.1 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 CBZ35849.1 - 3.1e-08 33.6 0.0 5.1e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CBZ35849.1 - 7.5e-08 32.2 0.0 9e-08 32.0 0.0 1.3 1 1 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.6 CBZ35849.1 - 9.7e-06 26.0 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CBZ35849.1 - 0.0013 18.6 0.0 0.0097 15.7 0.0 1.9 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CBZ35849.1 - 0.0018 18.1 0.0 0.086 12.6 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CBZ35849.1 - 0.0018 18.4 0.0 0.0026 17.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like DUF953 PF06110.11 CBZ35849.1 - 0.044 13.4 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF953) EF-hand_7 PF13499.6 CBZ35850.1 - 1e-07 32.3 0.0 9.8e-07 29.1 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ35850.1 - 0.00066 19.0 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CBZ35850.1 - 0.0008 19.1 0.1 0.0017 18.1 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 CBZ35850.1 - 0.0033 17.2 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CBZ35850.1 - 0.066 12.7 0.2 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 EF hand Thioredoxin_8 PF13905.6 CBZ35851.1 - 0.00034 20.9 0.0 1.2 9.6 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like PRIMA1 PF16101.5 CBZ35851.1 - 0.017 15.2 0.3 0.17 12.0 0.3 2.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF572 PF04502.13 CBZ35855.1 - 1.8e-16 60.7 10.5 4.7e-16 59.3 10.5 1.7 1 1 0 1 1 1 1 Family of unknown function (DUF572) Sec16_C PF12931.7 CBZ35856.1 - 1.4e-15 57.8 0.0 2.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 GPHH PF16905.5 CBZ35856.1 - 0.043 13.6 0.2 0.41 10.4 0.1 2.7 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated HSP70 PF00012.20 CBZ35857.1 - 3.6e-23 81.6 7.1 1.7e-22 79.4 0.0 2.4 1 1 1 2 2 2 1 Hsp70 protein TPR_1 PF00515.28 CBZ35857.1 - 5.8e-11 41.7 0.1 3.2e-06 26.7 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ35857.1 - 9.4e-10 37.9 0.3 6.5e-05 22.8 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ35857.1 - 4.1e-07 29.7 0.2 0.0001 22.2 0.1 3.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ35857.1 - 7.6e-07 29.3 2.3 5.2e-05 23.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ35857.1 - 1.7e-06 27.6 0.6 0.083 13.0 0.1 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ35857.1 - 2.8e-06 27.9 0.2 4.2e-05 24.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ35857.1 - 1.9e-05 24.7 0.1 0.00028 21.0 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ35857.1 - 0.00014 21.5 0.6 0.017 14.8 0.0 2.8 1 1 1 2 2 2 2 TPR repeat TPR_19 PF14559.6 CBZ35857.1 - 0.00016 22.1 0.7 0.0012 19.3 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ35857.1 - 0.0016 18.6 0.6 0.0041 17.3 0.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBZ35857.1 - 0.0032 17.7 0.4 0.011 16.0 0.1 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat ANAPC5 PF12862.7 CBZ35857.1 - 0.0038 17.3 1.1 0.06 13.4 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 CBZ35857.1 - 0.02 14.8 0.2 0.2 11.6 0.2 2.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ35857.1 - 0.13 13.1 0.8 1 10.4 0.2 3.0 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ35857.1 - 0.39 11.5 7.3 0.22 12.3 0.7 3.9 5 0 0 5 5 2 0 Tetratricopeptide repeat Cob_adeno_trans PF01923.18 CBZ35857.1 - 7.5 6.7 9.5 4.2 7.5 3.7 3.1 3 1 0 3 3 3 0 Cobalamin adenosyltransferase DUF4357 PF14267.6 CBZ35858.1 - 5.1 7.1 11.0 0.88 9.6 1.4 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4357) Lipase_3 PF01764.25 CBZ35859.1 - 2.2e-25 89.2 0.0 4.3e-18 65.5 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) MIG-14_Wnt-bd PF06664.12 CBZ35859.1 - 5.7e-08 32.3 3.5 6.6e-08 32.1 2.1 1.8 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion Abhydrolase_5 PF12695.7 CBZ35859.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_2 PF07724.14 CBZ35860.1 - 5.4e-57 192.6 0.1 2.9e-54 183.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CBZ35860.1 - 1.5e-36 124.5 1.8 1.5e-36 124.5 1.8 2.8 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 CBZ35860.1 - 6.2e-27 94.6 0.0 5.7e-15 55.9 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CBZ35860.1 - 1e-20 73.5 0.1 1e-20 73.5 0.1 3.3 4 0 0 4 4 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CBZ35860.1 - 4.5e-15 55.8 0.3 2.5e-10 40.5 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CBZ35860.1 - 2.5e-11 43.5 9.8 7.5e-06 26.0 2.0 3.7 3 0 0 3 3 3 2 Clp amino terminal domain, pathogenicity island component AAA_22 PF13401.6 CBZ35860.1 - 9.4e-09 35.7 0.1 0.025 14.9 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ35860.1 - 4.6e-08 33.6 11.4 0.001 19.5 0.1 5.1 3 3 0 4 4 4 2 AAA ATPase domain Sigma54_activat PF00158.26 CBZ35860.1 - 6.1e-08 32.6 0.0 4.9e-05 23.1 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CBZ35860.1 - 4.2e-07 30.1 0.0 0.021 14.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain TniB PF05621.11 CBZ35860.1 - 5.1e-07 29.3 0.0 0.0004 19.9 0.0 3.4 2 1 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 CBZ35860.1 - 6.1e-07 29.3 0.0 0.02 14.6 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 CBZ35860.1 - 1.3e-06 28.2 1.5 0.3 10.8 0.0 4.6 4 1 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CBZ35860.1 - 6.7e-06 25.7 0.0 0.033 13.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region ATPase_2 PF01637.18 CBZ35860.1 - 7.8e-05 22.7 7.3 0.71 9.7 0.2 4.3 3 1 1 4 4 4 2 ATPase domain predominantly from Archaea NACHT PF05729.12 CBZ35860.1 - 9.7e-05 22.3 0.0 0.14 12.1 0.0 3.8 4 0 0 4 4 3 1 NACHT domain AAA_18 PF13238.6 CBZ35860.1 - 0.0001 22.9 0.3 0.26 11.8 0.0 3.8 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CBZ35860.1 - 0.00016 21.0 1.5 0.12 11.6 0.0 4.2 5 0 0 5 5 4 1 Zeta toxin AAA_33 PF13671.6 CBZ35860.1 - 0.00035 20.8 0.6 0.38 10.9 0.0 3.9 4 0 0 4 4 4 1 AAA domain Roc PF08477.13 CBZ35860.1 - 0.00036 20.8 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CBZ35860.1 - 0.00064 20.3 15.4 0.34 11.4 6.6 4.3 3 1 0 3 3 3 1 AAA domain TsaE PF02367.17 CBZ35860.1 - 0.00073 19.5 0.0 2.4 8.1 0.0 2.9 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CBZ35860.1 - 0.00075 19.1 4.2 0.24 10.9 0.0 3.9 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CBZ35860.1 - 0.0011 19.4 0.2 1.7 9.1 0.0 3.2 4 0 0 4 4 2 1 RNA helicase TIP49 PF06068.13 CBZ35860.1 - 0.0012 18.2 0.1 0.33 10.1 0.0 3.0 2 1 1 3 3 3 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CBZ35860.1 - 0.0012 18.2 0.1 3.9 6.8 0.1 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CBZ35860.1 - 0.0013 17.9 0.1 0.28 10.3 0.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 CBZ35860.1 - 0.0039 17.1 0.1 6.6 6.6 0.0 3.2 2 1 0 3 3 3 0 RsgA GTPase AAA_3 PF07726.11 CBZ35860.1 - 0.0043 16.9 0.1 1.8 8.4 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CBZ35860.1 - 0.0054 16.5 0.9 1.1 9.0 0.0 3.3 3 1 0 3 3 2 1 DNA polymerase III, delta subunit NTPase_1 PF03266.15 CBZ35860.1 - 0.0072 16.3 0.3 2.3 8.1 0.0 3.4 3 0 0 3 3 3 1 NTPase ResIII PF04851.15 CBZ35860.1 - 0.0077 16.3 0.0 0.86 9.6 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 CBZ35860.1 - 0.012 16.1 1.9 15 6.1 0.0 4.0 4 1 0 4 4 3 0 ABC transporter Bac_DnaA PF00308.18 CBZ35860.1 - 0.016 15.1 0.0 10 5.9 0.0 3.0 2 1 0 2 2 2 0 Bacterial dnaA protein AAA_19 PF13245.6 CBZ35860.1 - 0.017 15.5 1.6 0.73 10.2 0.1 3.5 2 2 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CBZ35860.1 - 0.019 14.7 0.0 11 5.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 CBZ35860.1 - 0.052 13.8 0.1 26 5.0 0.0 3.5 3 0 0 3 3 2 0 AAA domain Spc7 PF08317.11 CBZ35860.1 - 0.39 9.6 15.8 0.86 8.4 15.8 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CBZ35860.1 - 0.6 8.0 4.1 0.93 7.3 4.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF16 PF01519.16 CBZ35860.1 - 2.6 8.6 11.5 2.5 8.7 3.7 3.4 2 1 1 3 3 2 0 Protein of unknown function DUF16 Lipase_3 PF01764.25 CBZ35861.1 - 4.4e-23 81.7 0.0 1e-22 80.5 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) MIG-14_Wnt-bd PF06664.12 CBZ35861.1 - 7.1e-08 32.0 27.7 1.2e-07 31.3 27.7 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DSS1_SEM1 PF05160.13 CBZ35862.1 - 0.11 12.6 12.1 0.24 11.5 12.1 1.7 1 1 0 1 1 1 0 DSS1/SEM1 family Carn_acyltransf PF00755.20 CBZ35864.1 - 4.9e-117 392.0 0.0 5.9e-117 391.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase RNA_pol_Rpc34 PF05158.12 CBZ35865.1 - 2.2e-53 181.8 0.0 2.1e-52 178.6 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit TFIIE_alpha PF02002.17 CBZ35865.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 TFIIE alpha subunit GNVR PF13807.6 CBZ35865.1 - 0.097 12.6 0.2 0.18 11.7 0.2 1.4 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Rrf2 PF02082.20 CBZ35865.1 - 0.1 13.0 0.7 6.8 7.1 0.1 2.9 3 0 0 3 3 3 0 Transcriptional regulator Pkinase PF00069.25 CBZ35866.1 - 1.3e-61 208.3 0.0 5.9e-61 206.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35866.1 - 6.2e-33 114.2 0.0 1.4e-23 83.5 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 CBZ35866.1 - 0.0011 18.4 0.2 0.0021 17.4 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ35866.1 - 0.011 14.7 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBZ35866.1 - 0.039 13.9 0.3 0.078 12.9 0.3 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ35866.1 - 0.078 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 CBZ35868.1 - 1.3e-32 111.4 0.0 1.2e-19 69.8 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ35868.1 - 1.7e-05 24.8 0.0 0.00039 20.5 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 CBZ35868.1 - 0.00078 19.3 0.0 0.4 10.6 0.0 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CBZ35868.1 - 0.0015 18.1 0.0 0.0064 16.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBZ35868.1 - 0.0025 17.9 0.0 0.02 15.0 0.0 2.5 3 0 0 3 3 3 1 Limkain b1 RRM_8 PF11835.8 CBZ35868.1 - 0.0061 16.7 0.0 2.4 8.4 0.0 3.0 2 1 0 2 2 2 1 RRM-like domain RRM_3 PF08777.11 CBZ35868.1 - 0.016 15.2 0.0 2.9 8.0 0.0 2.7 2 1 0 2 2 2 0 RNA binding motif RRM_1 PF00076.22 CBZ35872.1 - 3.4e-23 81.3 0.0 6.6e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBZ35873.1 - 1e-25 89.4 0.0 2.6e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ35873.1 - 0.017 15.2 0.0 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif RRM_1 PF00076.22 CBZ35874.1 - 5.5e-26 90.2 0.0 4.5e-14 52.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ35874.1 - 0.0016 18.5 0.0 0.24 11.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif PHM7_cyt PF14703.6 CBZ35874.1 - 0.078 13.2 0.3 79 3.4 0.1 3.5 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 CBZ35876.1 - 3.8e-20 71.5 0.1 2.1e-13 49.9 0.1 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ35876.1 - 0.005 16.9 0.1 4.5 7.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RNA_bind PF08675.11 CBZ35876.1 - 0.072 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA binding domain zf-LYAR PF08790.11 CBZ35877.1 - 1.8e-13 50.1 1.8 1.8e-13 50.1 1.8 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 CBZ35877.1 - 0.15 11.7 0.4 8.3 6.1 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-DNL PF05180.12 CBZ35877.1 - 0.94 9.5 5.5 2 8.4 5.5 1.5 1 0 0 1 1 1 0 DNL zinc finger Clat_adaptor_s PF01217.20 CBZ35879.1 - 5.9e-49 165.7 1.2 7e-49 165.4 1.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PI3_PI4_kinase PF00454.27 CBZ35881.1 - 2e-35 122.8 0.0 3.1e-32 112.4 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CBZ35881.1 - 6.5e-16 58.3 0.3 2e-15 56.7 0.1 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 CBZ35881.1 - 0.033 13.5 0.0 0.077 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Ank_2 PF12796.7 CBZ35883.1 - 3e-05 24.5 0.2 9e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CBZ35883.1 - 0.0025 18.1 0.2 2.1 8.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ35883.1 - 0.077 13.6 1.3 5 8.0 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 CBZ35883.1 - 0.11 13.1 1.1 1.1 9.9 0.1 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Nodulin-like PF06813.13 CBZ35886.1 - 7.9e-09 35.4 17.5 8.2e-09 35.3 13.4 2.9 2 1 0 2 2 2 1 Nodulin-like MFS_1 PF07690.16 CBZ35886.1 - 2.7e-08 33.1 38.3 9.9e-06 24.7 19.6 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CBZ35887.1 - 1.1e-21 77.1 19.0 1.9e-13 50.1 17.0 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ35887.1 - 5.6e-12 45.7 14.7 5.6e-12 45.7 14.7 2.6 2 1 0 2 2 2 1 Nodulin-like MFS_1 PF07690.16 CBZ35888.1 - 0.00017 20.6 9.4 0.00021 20.4 9.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily RabGAP-TBC PF00566.18 CBZ35893.1 - 5.3e-43 147.2 0.0 7.2e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M20 PF01546.28 CBZ35894.1 - 2e-36 125.6 0.0 2.6e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ35894.1 - 1.6e-18 66.6 0.0 2.7e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.14 CBZ35894.1 - 0.15 11.1 0.0 1.3 8.0 0.0 2.3 2 1 1 3 3 3 0 M42 glutamyl aminopeptidase WD40 PF00400.32 CBZ35895.1 - 7.1e-06 26.7 0.0 0.006 17.4 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ35895.1 - 2.5e-05 24.5 0.0 0.0019 18.5 0.0 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain XPC-binding PF09280.11 CBZ35896.1 - 8.9e-07 28.6 3.2 2.1e-06 27.4 3.2 1.7 1 1 0 1 1 1 1 XPC-binding domain UBA PF00627.31 CBZ35896.1 - 2.7e-06 27.2 0.0 8e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain MmoB_DmpM PF02406.17 CBZ35896.1 - 0.051 13.8 0.3 13 6.1 0.0 2.6 2 0 0 2 2 2 0 MmoB/DmpM family RNA_pol_3_Rpc31 PF11705.8 CBZ35896.1 - 0.93 9.7 11.7 3 8.1 5.4 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 CBZ35896.1 - 1.6 8.4 10.7 0.044 13.5 2.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 CBZ35896.1 - 3 7.9 6.8 4.5 7.3 2.7 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal FAM176 PF14851.6 CBZ35896.1 - 4 7.1 7.9 4.5 6.9 1.2 2.5 2 0 0 2 2 2 0 FAM176 family EMP70 PF02990.16 CBZ35899.1 - 2.3e-152 508.3 14.8 2.9e-152 508.0 14.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 SYS1 PF09801.9 CBZ35901.1 - 1.1e-20 74.3 3.2 5.3e-19 68.8 1.1 2.2 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network PAP2 PF01569.21 CBZ35901.1 - 2.2 8.0 6.5 0.31 10.8 2.2 1.7 2 0 0 2 2 2 0 PAP2 superfamily dsrm PF00035.26 CBZ35902.1 - 4.7e-08 33.6 0.0 1.9 9.2 0.0 5.8 5 0 0 5 5 5 3 Double-stranded RNA binding motif DNA_pol_phi PF04931.13 CBZ35902.1 - 6.6 4.7 7.7 10 4.1 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi RINGv PF12906.7 CBZ35903.1 - 4.3e-11 42.8 8.9 9.7e-11 41.6 8.9 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CBZ35903.1 - 0.069 13.5 7.6 0.13 12.6 7.6 1.5 1 0 0 1 1 1 0 Ring finger domain Phage_holin_2_4 PF16082.5 CBZ35903.1 - 0.31 10.8 3.2 0.81 9.5 0.3 2.5 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like zf-RING-like PF08746.11 CBZ35903.1 - 3.4 8.0 6.8 6.2 7.2 6.8 1.4 1 0 0 1 1 1 0 RING-like domain ABC_tran PF00005.27 CBZ35904.1 - 2.6e-27 96.0 0.0 5.3e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBZ35904.1 - 8.3e-07 29.1 0.9 0.0002 21.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ35904.1 - 0.0012 18.3 0.1 0.013 14.9 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBZ35904.1 - 0.035 14.0 0.0 0.092 12.6 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase RuvB_N PF05496.12 CBZ35904.1 - 0.049 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ35904.1 - 0.054 13.9 0.1 0.11 12.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 CBZ35904.1 - 0.1 12.9 0.3 1.6 9.0 0.3 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CBZ35904.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CBZ35904.1 - 0.11 12.3 0.0 5 6.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein T6SS_VipA PF05591.12 CBZ35904.1 - 0.12 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 AAA_10 PF12846.7 CBZ35904.1 - 0.15 10.9 0.0 8.5 5.2 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.29 CBZ35904.1 - 0.28 11.6 1.1 8.6 6.8 1.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thioredoxin PF00085.20 CBZ35905.1 - 1.5e-06 28.1 0.0 1.9e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin FUSC PF04632.12 CBZ35906.1 - 0.51 8.8 6.7 0.63 8.5 6.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family 4HBT PF03061.22 CBZ35907.1 - 1.1e-14 54.5 3.8 1.9e-09 37.7 0.7 2.5 2 0 0 2 2 2 2 Thioesterase superfamily 4HBT_2 PF13279.6 CBZ35907.1 - 0.0052 17.3 0.5 0.59 10.6 0.2 2.4 1 1 0 2 2 2 1 Thioesterase-like superfamily MaoC_dehydratas PF01575.19 CBZ35907.1 - 0.029 13.9 0.1 1.1 8.9 0.1 2.9 3 0 0 3 3 3 0 MaoC like domain Cas_Csx8 PF09657.10 CBZ35907.1 - 0.09 11.7 0.2 0.13 11.2 0.2 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) MORN PF02493.20 CBZ35908.1 - 2.1e-48 159.4 103.3 4.3e-07 29.5 2.2 21.7 22 0 0 22 22 22 17 MORN repeat DUF2671 PF10877.8 CBZ35908.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2671) MutS_III PF05192.18 CBZ35909.1 - 2.1e-16 60.7 0.0 4.7e-16 59.6 0.0 1.6 1 1 0 1 1 1 1 MutS domain III MutS_V PF00488.21 CBZ35909.1 - 4.5e-15 56.2 1.7 8.9e-08 32.4 0.1 2.7 3 0 0 3 3 3 2 MutS domain V AAA_29 PF13555.6 CBZ35909.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CBZ35909.1 - 0.02 14.7 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ35909.1 - 0.028 14.8 0.0 0.1 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 CBZ35909.1 - 0.078 12.4 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 CBZ35909.1 - 0.093 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Flagellar_rod PF05149.12 CBZ35914.1 - 1.4e-103 346.4 28.1 1.4e-103 346.4 28.1 2.9 2 1 1 3 3 3 2 Paraflagellar rod protein DUF1120 PF06551.12 CBZ35914.1 - 0.16 12.2 1.0 0.32 11.2 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1120) Diphthamide_syn PF01866.17 CBZ35915.1 - 4.7e-113 377.6 0.0 5.9e-113 377.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein BRCT PF00533.26 CBZ35916.1 - 6.6e-09 36.0 0.0 0.12 12.8 0.0 4.5 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 CBZ35916.1 - 2.4e-07 30.6 0.0 1.5e-06 28.0 0.0 2.4 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 CBZ35916.1 - 0.00017 21.5 4.3 1.4 8.9 0.0 5.1 5 1 0 5 5 5 2 twin BRCT domain BRCT_2 PF16589.5 CBZ35916.1 - 0.00036 20.9 0.0 1.6 9.2 0.0 3.5 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain Pullulanase_N2 PF17967.1 CBZ35916.1 - 0.075 13.9 0.1 0.19 12.6 0.1 1.7 1 0 0 1 1 1 0 Pullulanase N2 domain BRCT_3 PF18428.1 CBZ35916.1 - 0.097 12.7 2.8 2.6 8.2 0.1 3.5 4 0 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain Ribosomal_S8 PF00410.19 CBZ35917.1 - 5.4e-21 74.9 0.0 6.8e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Folliculin_C PF16692.5 CBZ35918.1 - 2.5e-08 33.9 0.0 4.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Folliculin C-terminal domain Folliculin PF11704.8 CBZ35918.1 - 3.6e-08 33.5 0.0 8.8e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Bac_surface_Ag PF01103.23 CBZ35919.1 - 4.2e-20 72.5 0.6 5.1e-20 72.2 0.6 1.2 1 0 0 1 1 1 1 Surface antigen Pyr_redox_2 PF07992.14 CBZ35920.1 - 3.6e-46 157.7 0.2 4.9e-46 157.3 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBZ35920.1 - 9.8e-21 74.1 0.1 3.5e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBZ35920.1 - 3.3e-19 69.2 1.0 1.5e-16 60.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CBZ35920.1 - 2.9e-10 40.1 0.3 4.9e-10 39.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CBZ35920.1 - 1.1e-07 31.4 0.1 0.029 13.6 0.0 3.3 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_3 PF13738.6 CBZ35920.1 - 3.4e-07 29.8 8.7 0.0035 16.7 0.6 3.4 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ35920.1 - 1e-06 27.7 1.3 0.00084 18.1 0.4 3.3 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 CBZ35920.1 - 8.1e-06 25.2 5.3 0.066 12.3 2.8 3.7 3 1 0 3 3 3 2 Glucose inhibited division protein A K_oxygenase PF13434.6 CBZ35920.1 - 8.9e-06 25.1 0.0 4e-05 22.9 0.0 1.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CBZ35920.1 - 6.1e-05 22.4 0.3 0.0079 15.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 CBZ35920.1 - 0.00014 21.2 0.1 0.32 10.3 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CBZ35920.1 - 0.00038 20.2 11.7 0.0071 16.0 0.3 3.4 2 2 1 3 3 3 2 FAD dependent oxidoreductase ThiF PF00899.21 CBZ35920.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.24 CBZ35920.1 - 0.0019 17.4 1.4 0.0019 17.4 1.4 2.9 2 1 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 CBZ35920.1 - 0.0042 17.3 4.1 0.43 10.8 0.8 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 CBZ35920.1 - 0.0077 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CBZ35920.1 - 0.012 15.0 0.0 0.045 13.1 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 CBZ35920.1 - 0.012 14.7 1.0 0.69 8.9 0.3 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 CBZ35920.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Snapin_Pallidin PF14712.6 CBZ35921.1 - 0.012 16.1 24.5 0.22 12.0 1.2 4.6 1 1 3 4 4 4 0 Snapin/Pallidin Myb_DNA-bind_4 PF13837.6 CBZ35921.1 - 0.031 14.6 0.6 0.1 13.0 0.6 1.9 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain PIN_8 PF18476.1 CBZ35921.1 - 0.046 13.6 12.7 0.56 10.0 2.5 2.3 1 1 1 2 2 2 0 PIN like domain Glyco_hydro_67C PF07477.12 CBZ35921.1 - 0.055 13.0 0.5 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 C-terminus XPG_N PF00752.17 CBZ35921.1 - 0.081 13.4 0.1 0.25 11.8 0.0 1.8 2 0 0 2 2 2 0 XPG N-terminal domain Sugarporin_N PF11471.8 CBZ35921.1 - 0.21 11.5 7.1 5.5 7.0 1.2 3.3 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension FlaC_arch PF05377.11 CBZ35921.1 - 0.26 11.7 9.4 1.1 9.7 0.1 4.7 4 1 3 7 7 7 0 Flagella accessory protein C (FlaC) ETF_alpha PF00766.19 CBZ35921.1 - 0.33 11.0 2.1 1.6 8.8 0.2 2.7 3 1 0 3 3 2 0 Electron transfer flavoprotein FAD-binding domain DUF1664 PF07889.12 CBZ35921.1 - 0.37 10.8 16.5 0.21 11.6 4.2 3.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) SNN_linker PF09050.10 CBZ35921.1 - 0.64 9.8 4.1 31 4.4 0.2 3.5 3 0 0 3 3 3 0 Stannin unstructured linker TolA_bind_tri PF16331.5 CBZ35921.1 - 1.5 8.9 33.4 1.5 9.0 2.9 4.8 2 1 2 4 4 3 0 TolA binding protein trimerisation Baculo_PEP_C PF04513.12 CBZ35921.1 - 1.8 8.6 10.0 0.34 11.0 0.6 3.2 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1993 PF09351.10 CBZ35921.1 - 2.1 8.5 8.1 1.3 9.2 3.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) Cupin_8 PF13621.6 CBZ35921.1 - 2.2 8.0 3.9 0.47 10.1 0.8 1.5 2 0 0 2 2 2 0 Cupin-like domain Baculo_F PF12259.8 CBZ35921.1 - 2.3 6.7 6.8 6.8 5.1 5.0 2.0 1 1 1 2 2 2 0 Baculovirus F protein FapA PF03961.13 CBZ35921.1 - 3.4 6.2 13.0 0.86 8.1 0.9 2.2 1 1 0 2 2 2 0 Flagellar Assembly Protein A DOG1 PF14144.6 CBZ35921.1 - 3.6 7.9 8.7 1.4 9.1 0.9 3.6 3 1 1 4 4 4 0 Seed dormancy control Fib_alpha PF08702.10 CBZ35921.1 - 4.1 7.6 18.5 4.8 7.4 4.5 3.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.8 CBZ35921.1 - 6.1 7.0 10.0 11 6.1 0.5 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) XhlA PF10779.9 CBZ35921.1 - 9.8 6.5 7.6 2.6 8.3 0.6 3.2 2 2 1 3 3 3 0 Haemolysin XhlA ING PF12998.7 CBZ35921.1 - 9.9 6.8 12.3 1.5 9.5 1.9 3.0 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding PIH1_CS PF18201.1 CBZ35922.1 - 1.4e-09 38.2 0.1 2.3e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 PIH1 CS-like domain zf_C2H2_10 PF18414.1 CBZ35924.1 - 0.018 14.6 0.1 0.026 14.1 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger zf-met2 PF12907.7 CBZ35924.1 - 0.11 12.6 2.9 1.1 9.5 2.9 2.3 1 1 0 1 1 1 0 Zinc-binding zf-C2H2_12 PF18658.1 CBZ35924.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger C2H2-type DnaJ PF00226.31 CBZ35926.1 - 1.2e-07 31.8 0.0 2.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain zf-ribbon_3 PF13248.6 CBZ35927.1 - 0.012 15.0 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 CBZ35927.1 - 0.033 13.9 0.2 0.067 12.9 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain BID PF06393.11 CBZ35927.1 - 0.12 11.9 0.4 0.46 10.0 0.1 1.9 2 0 0 2 2 2 0 BH3 interacting domain (BID) Rieske PF00355.26 CBZ35927.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain DNA_ligase_ZBD PF03119.16 CBZ35927.1 - 0.15 12.1 1.1 0.32 11.0 1.1 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Zn_ribbon_recom PF13408.6 CBZ35927.1 - 0.17 12.4 1.6 0.35 11.4 1.6 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-HIT PF04438.16 CBZ35927.1 - 0.96 9.4 3.2 0.41 10.6 0.5 1.7 2 0 0 2 2 2 0 HIT zinc finger Zn_ribbon_SprT PF17283.2 CBZ35927.1 - 3.4 7.7 5.3 2.9 7.9 0.8 1.8 1 1 1 2 2 2 0 SprT-like zinc ribbon domain EF-hand_7 PF13499.6 CBZ35930.1 - 8.1e-13 48.6 0.1 0.0035 17.7 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 CBZ35930.1 - 0.0004 20.1 0.2 0.73 9.9 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 CBZ35930.1 - 0.0017 17.7 0.3 0.41 10.3 0.1 3.6 4 0 0 4 4 4 1 EF hand DUF5315 PF17242.2 CBZ35931.1 - 0.14 12.0 0.3 0.26 11.1 0.3 1.4 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) PPTA PF01239.22 CBZ35932.1 - 6.7e-17 60.6 11.4 2.3e-06 27.2 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 CBZ35932.1 - 3.1 7.6 5.8 26 4.6 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) Fumerase_C PF05683.12 CBZ35933.1 - 1.4e-88 295.6 0.0 2.4e-88 294.9 0.0 1.4 1 0 0 1 1 1 1 Fumarase C-terminus Fumerase PF05681.14 CBZ35933.1 - 1.7e-80 270.3 0.0 2.2e-80 270.0 0.0 1.1 1 0 0 1 1 1 1 Fumarate hydratase (Fumerase) BRCT_2 PF16589.5 CBZ35934.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain DUF2935 PF11155.8 CBZ35935.1 - 0.0022 18.3 0.0 1.1 9.6 0.0 4.8 4 1 0 4 4 4 1 Domain of unknown function (DUF2935) Methyltr_RsmB-F PF01189.17 CBZ35937.1 - 1.9e-12 47.2 0.0 1.2e-08 34.9 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F UL45 PF05473.12 CBZ35937.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like PPR_2 PF13041.6 CBZ35938.1 - 3.7e-06 27.0 0.0 0.0066 16.6 0.0 3.7 3 1 1 4 4 4 2 PPR repeat family PPR_3 PF13812.6 CBZ35938.1 - 0.00064 19.7 0.0 1.1 9.3 0.0 3.5 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 CBZ35938.1 - 0.0026 17.9 0.0 9.6 6.7 0.0 4.2 5 0 0 5 5 5 1 PPR repeat SPG48 PF14764.6 CBZ35938.1 - 0.007 16.8 0.2 0.45 11.0 0.2 2.7 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking Pkinase PF00069.25 CBZ35939.1 - 1.3e-73 247.6 0.0 1.8e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35939.1 - 7.7e-40 136.8 0.0 1.1e-39 136.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ35939.1 - 1.3e-06 27.9 0.0 7.7e-06 25.4 0.0 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 CBZ35939.1 - 2.7e-05 23.9 0.3 0.00067 19.3 0.0 2.1 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 CBZ35939.1 - 0.00013 21.4 0.1 0.00023 20.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ35939.1 - 0.00062 18.8 0.1 0.001 18.1 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CBZ35939.1 - 0.0021 18.0 0.3 0.15 11.9 0.1 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Gpi1 PF05024.15 CBZ35940.1 - 1.6e-38 132.7 3.1 4.5e-38 131.2 3.1 1.8 1 1 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Hpt PF01627.23 CBZ35944.1 - 0.048 13.9 0.5 0.098 12.9 0.5 1.5 1 0 0 1 1 1 0 Hpt domain adh_short PF00106.25 CBZ35945.1 - 8.1e-05 22.2 0.0 0.0051 16.3 0.1 2.9 2 1 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 CBZ35945.1 - 0.039 13.4 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase AAA_12 PF13087.6 CBZ35946.1 - 2.7e-32 112.0 0.0 4.3e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CBZ35946.1 - 3.1e-15 56.7 0.1 1.5e-09 38.0 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CBZ35946.1 - 1.9e-07 31.0 3.8 0.0011 18.7 0.0 3.6 3 1 1 4 4 4 2 AAA domain AAA_19 PF13245.6 CBZ35946.1 - 7.5e-06 26.3 0.4 0.35 11.2 0.4 3.3 2 1 0 2 2 2 2 AAA domain PhoH PF02562.16 CBZ35946.1 - 0.00021 20.8 0.1 0.15 11.5 0.0 3.1 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.6 CBZ35946.1 - 0.00036 20.8 0.2 1 9.6 0.0 4.3 4 1 0 4 4 4 1 AAA domain AAA_33 PF13671.6 CBZ35946.1 - 0.003 17.7 0.0 5.5 7.2 0.0 3.2 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CBZ35946.1 - 0.0095 15.7 0.9 3.5 7.3 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CBZ35946.1 - 0.018 14.3 0.2 0.04 13.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) zf-C2H2_10 PF16588.5 CBZ35946.1 - 0.02 14.6 5.0 0.035 13.8 5.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger CSD PF00313.22 CBZ35946.1 - 0.2 11.6 0.1 0.55 10.1 0.1 1.8 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain AAA_16 PF13191.6 CBZ35946.1 - 0.71 10.2 3.4 1.2 9.5 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain DUF4139 PF13598.6 CBZ35947.1 - 1.2e-31 110.1 0.0 2.1e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) Glyco_transf_24 PF18404.1 CBZ35948.1 - 1.6e-131 437.6 1.9 2.3e-131 437.1 1.9 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CBZ35948.1 - 1.8e-38 133.0 0.0 7.8e-35 121.0 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CBZ35948.1 - 3.5e-22 78.8 0.0 4.9e-20 71.8 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CBZ35948.1 - 1.9e-13 50.4 0.0 4.3e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_12 PF18400.1 CBZ35948.1 - 1.4e-11 44.6 0.0 4e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 CBZ35948.1 - 8.2e-07 28.8 0.1 1.9e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 Thioredoxin_15 PF18403.1 CBZ35948.1 - 0.0092 15.9 0.0 0.63 9.9 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain LRR_4 PF12799.7 CBZ35949.1 - 1.2e-09 38.3 19.2 0.0042 17.5 0.5 6.1 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) FNIP PF05725.12 CBZ35949.1 - 3e-06 27.3 6.0 0.53 10.5 0.1 4.7 3 1 0 4 4 4 3 FNIP Repeat LRR_8 PF13855.6 CBZ35949.1 - 3.3e-06 26.8 14.7 0.036 13.8 0.6 4.5 2 2 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 CBZ35949.1 - 3.4e-06 26.7 10.3 0.24 11.5 0.0 7.1 8 0 0 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 CBZ35949.1 - 4e-05 23.6 18.1 10 7.1 0.1 7.9 6 3 0 6 6 6 3 Leucine Rich Repeat ERG2_Sigma1R PF04622.12 CBZ35950.1 - 1.3e-80 269.7 0.3 1.5e-80 269.5 0.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Pkinase PF00069.25 CBZ35951.1 - 7e-39 133.8 0.0 4.2e-36 124.7 0.0 3.6 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35951.1 - 1.6e-17 63.7 0.0 1e-15 57.8 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ35951.1 - 0.12 11.7 0.0 0.96 8.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like GDI PF00996.18 CBZ35952.1 - 3.8e-179 595.8 0.0 4.3e-179 595.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor DTW PF03942.15 CBZ35953.1 - 3.2e-32 111.9 0.1 5.6e-32 111.1 0.1 1.3 1 0 0 1 1 1 1 DTW domain DUF4379 PF14311.6 CBZ35954.1 - 3.2e-44 149.1 15.9 1.8e-15 57.0 3.2 3.4 3 0 0 3 3 3 3 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 CBZ35954.1 - 1.1e-05 25.5 10.6 0.1 12.7 0.1 3.6 3 0 0 3 3 3 3 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 CBZ35954.1 - 0.038 13.5 2.7 2.2 7.9 0.0 4.1 4 0 0 4 4 4 0 TFIIB zinc-binding Zn-C2H2_12 PF18112.1 CBZ35954.1 - 0.37 11.3 2.2 1.9 9.0 0.0 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Zn_Tnp_IS91 PF14319.6 CBZ35954.1 - 3.1 7.9 13.6 0.12 12.4 0.4 3.6 3 2 0 3 3 3 0 Transposase zinc-binding domain DUF2072 PF09845.9 CBZ35954.1 - 3.7 7.8 6.8 0.33 11.2 0.3 2.6 3 0 0 3 3 3 0 Zn-ribbon containing protein zinc_ribbon_10 PF10058.9 CBZ35954.1 - 5.6 6.8 9.8 36 4.2 0.0 4.3 5 0 0 5 5 5 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-C3HC4_3 PF13920.6 CBZ35954.1 - 7.8 6.4 18.5 5.1 7.0 1.8 4.0 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Dynamin_M PF01031.20 CBZ35956.1 - 5.3e-81 272.0 0.3 1.2e-80 270.8 0.3 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CBZ35956.1 - 1.5e-50 171.6 0.1 3.5e-50 170.3 0.1 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CBZ35956.1 - 3.8e-25 87.9 0.2 1.3e-24 86.2 0.2 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CBZ35956.1 - 9e-05 22.5 0.2 0.00094 19.3 0.2 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AF0941-like PF14591.6 CBZ35956.1 - 0.017 15.7 1.7 4.8 7.8 0.6 3.1 2 1 0 2 2 2 0 AF0941-like FeoB_N PF02421.18 CBZ35956.1 - 0.019 14.5 0.3 4.3 6.9 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Baculo_p74 PF04583.12 CBZ35956.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Baculoviridae p74 conserved region AAA_15 PF13175.6 CBZ35956.1 - 0.25 11.0 1.8 0.58 9.8 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain LRR_9 PF14580.6 CBZ35957.1 - 3.3e-18 65.8 0.2 4.7e-18 65.3 0.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBZ35957.1 - 6.7e-12 45.4 3.7 3.1e-05 24.2 0.4 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ35957.1 - 1.1e-08 34.8 3.1 2.3e-07 30.5 0.8 3.2 2 2 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 CBZ35957.1 - 0.00047 20.0 1.2 2.3 8.5 0.1 3.5 3 0 0 3 3 3 2 Leucine Rich repeat TIG_plexin PF17960.1 CBZ35957.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 TIG domain LRR_1 PF00560.33 CBZ35957.1 - 0.4 11.4 6.1 1.9e+02 3.3 0.0 4.6 3 1 1 4 4 4 0 Leucine Rich Repeat Myosin_TH1 PF06017.13 CBZ35958.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding Peptidase_M1 PF01433.20 CBZ35960.1 - 4.7e-65 219.2 0.0 7.5e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CBZ35960.1 - 7.2e-33 114.5 0.6 1.1e-32 113.9 0.6 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CBZ35960.1 - 1.7e-23 83.7 0.0 4.9e-23 82.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain CPCFC PF17223.3 CBZ35960.1 - 0.42 10.4 2.3 0.88 9.4 0.3 2.7 2 0 0 2 2 2 0 Cuticle protein CPCFC DUF4407 PF14362.6 CBZ35961.1 - 0.0041 16.5 9.6 0.0041 16.5 9.6 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 CBZ35961.1 - 0.011 15.9 1.5 0.011 15.9 1.5 3.9 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 LXG PF04740.12 CBZ35961.1 - 0.011 15.4 3.4 0.011 15.4 3.4 2.9 3 1 1 4 4 3 0 LXG domain of WXG superfamily Phage_GP20 PF06810.11 CBZ35961.1 - 0.067 13.0 21.7 0.033 14.0 4.5 3.3 4 0 0 4 4 4 0 Phage minor structural protein GP20 DUF1664 PF07889.12 CBZ35961.1 - 0.093 12.8 9.8 1.7 8.7 1.1 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF4600 PF15372.6 CBZ35961.1 - 0.094 13.1 11.8 0.91 10.0 1.9 3.0 3 0 0 3 3 2 0 Domain of unknown function (DUF4600) MCC-bdg_PDZ PF10506.9 CBZ35961.1 - 0.12 12.4 0.2 0.12 12.4 0.2 5.4 6 2 0 7 7 5 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Myc-LZ PF02344.15 CBZ35961.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.9 3 0 0 3 3 2 0 Myc leucine zipper domain Fmp27_WPPW PF10359.9 CBZ35961.1 - 0.2 10.5 13.3 0.39 9.5 2.8 2.4 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain TTKRSYEDQ PF10212.9 CBZ35961.1 - 0.37 9.7 10.7 0.015 14.3 1.5 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Tropomyosin PF00261.20 CBZ35961.1 - 0.38 10.1 26.3 0.033 13.6 3.7 3.6 4 0 0 4 4 4 0 Tropomyosin ADIP PF11559.8 CBZ35961.1 - 0.39 10.8 30.9 0.043 13.9 3.0 3.5 4 0 0 4 4 3 0 Afadin- and alpha -actinin-Binding LMBR1 PF04791.16 CBZ35961.1 - 0.5 9.2 3.1 2.4 7.0 2.2 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein Lebercilin PF15619.6 CBZ35961.1 - 0.5 10.0 26.7 1.3 8.7 3.6 3.5 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease APG6_N PF17675.1 CBZ35961.1 - 0.61 10.6 37.3 0.85 10.2 8.6 4.4 4 0 0 4 4 4 0 Apg6 coiled-coil region DHR10 PF18595.1 CBZ35961.1 - 0.61 10.1 38.1 0.16 12.1 3.6 4.1 5 0 0 5 5 3 0 Designed helical repeat protein 10 domain HALZ PF02183.18 CBZ35961.1 - 0.65 10.3 13.4 4.3 7.7 0.0 4.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper FH2 PF02181.23 CBZ35961.1 - 0.85 8.7 12.4 0.24 10.5 0.5 3.3 4 0 0 4 4 4 0 Formin Homology 2 Domain Fez1 PF06818.15 CBZ35961.1 - 1.2 9.5 24.8 0.24 11.8 14.7 3.3 2 1 1 3 3 3 0 Fez1 ACCA PF03255.14 CBZ35961.1 - 1.2 8.9 9.8 2.4 8.0 0.3 3.2 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Atg14 PF10186.9 CBZ35961.1 - 1.6 7.8 25.0 0.45 9.5 8.2 3.3 3 1 1 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 Striatin PF08232.12 CBZ35961.1 - 4.2 8.0 16.9 0.68 10.5 11.2 2.6 3 0 0 3 3 3 0 Striatin family DUF1465 PF07323.12 CBZ35961.1 - 4.4 7.1 17.3 0.34 10.7 0.8 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1465) DUF2968 PF11180.8 CBZ35961.1 - 4.7 6.8 30.5 0.072 12.7 10.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) YabA PF06156.13 CBZ35961.1 - 4.8 7.9 14.6 10 6.8 0.3 4.0 3 0 0 3 3 3 0 Initiation control protein YabA ATG16 PF08614.11 CBZ35961.1 - 5.3 7.2 38.2 0.68 10.1 11.2 4.1 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) CC2-LZ PF16516.5 CBZ35961.1 - 7.5 7.0 25.7 5.2 7.5 2.3 5.3 4 2 0 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator HMMR_N PF15905.5 CBZ35961.1 - 8.6 5.7 26.2 16 4.8 19.8 3.2 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Uso1_p115_C PF04871.13 CBZ35961.1 - 9.9 6.5 31.3 0.85 10.0 6.2 4.4 4 0 0 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region SLD5_C PF16922.5 CBZ35962.1 - 4e-09 36.5 0.0 7.9e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CBZ35962.1 - 0.0043 17.5 0.0 0.0085 16.6 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein Acyltransferase PF01553.21 CBZ35963.1 - 3.8e-09 36.3 0.3 8.2e-09 35.2 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase Acyltransferase PF01553.21 CBZ35964.1 - 2.5e-09 36.9 0.0 4.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Phage_holin_3_3 PF16083.5 CBZ35964.1 - 0.15 12.2 1.5 0.29 11.3 1.5 1.5 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III DUF1029 PF06269.12 CBZ35964.1 - 1 9.5 6.5 7.1 6.8 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1029) UCH PF00443.29 CBZ35966.1 - 1.7e-43 149.0 0.0 2.6e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 CBZ35966.1 - 8.5e-18 63.9 7.5 3.1e-16 58.9 5.7 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 CBZ35966.1 - 3e-17 62.7 27.5 1.7e-16 60.3 6.5 3.6 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CBZ35966.1 - 9.3e-14 51.7 0.0 4.7e-13 49.4 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CBZ35966.1 - 1e-05 25.3 0.2 3.4e-05 23.6 0.2 2.0 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 CBZ35966.1 - 0.039 13.8 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.16 CBZ35966.1 - 0.17 11.6 0.0 0.47 10.2 0.0 1.8 1 0 0 1 1 1 0 CUE domain ECH_1 PF00378.20 CBZ35967.1 - 1.1e-74 250.9 0.7 1.3e-74 250.7 0.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ35967.1 - 3.7e-36 125.3 0.6 1.9e-32 113.1 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CBZ35967.1 - 0.011 15.7 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 DUF5563 PF17718.1 CBZ35967.1 - 0.062 12.9 0.1 0.088 12.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5563) Pkinase PF00069.25 CBZ35968.1 - 1.2e-54 185.5 0.0 2.1e-54 184.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35968.1 - 2e-34 119.0 0.0 3.3e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CBZ35968.1 - 1.1e-05 24.5 0.4 0.0032 16.5 0.0 2.9 3 0 0 3 3 3 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CBZ35968.1 - 6.4e-05 21.9 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ35968.1 - 0.0004 20.4 0.0 0.12 12.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Ig_6 PF18452.1 CBZ35968.1 - 0.051 13.1 0.1 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 Immunoglobulin domain GET2 PF08690.10 CBZ35969.1 - 0.0014 18.3 0.5 0.0035 17.1 0.0 1.8 2 0 0 2 2 2 1 GET complex subunit GET2 DUF4407 PF14362.6 CBZ35969.1 - 0.018 14.4 4.2 0.12 11.8 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) GrpE PF01025.19 CBZ35969.1 - 0.071 12.8 0.4 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 GrpE NRN1 PF15056.6 CBZ35969.1 - 0.083 13.0 0.1 0.31 11.2 0.1 2.1 1 1 1 2 2 2 0 Neuritin protein family Sec34 PF04136.15 CBZ35969.1 - 0.93 9.4 4.1 5.1 7.0 0.1 3.1 3 1 0 3 3 3 0 Sec34-like family NAP PF00956.18 CBZ35970.1 - 4e-07 29.5 5.7 0.0061 15.8 0.0 3.0 1 1 2 3 3 3 3 Nucleosome assembly protein (NAP) Phage_Mu_Gam PF07352.12 CBZ35970.1 - 0.022 14.7 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein COQ7 PF03232.13 CBZ35971.1 - 4.2e-54 182.9 0.5 4.9e-54 182.7 0.5 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Peptidase_M18 PF02127.15 CBZ35972.1 - 7.1e-159 529.2 0.0 8.1e-159 529.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CBZ35972.1 - 2.8e-09 36.4 0.1 6.9e-07 28.6 0.1 2.2 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Ribosomal_L39 PF00832.20 CBZ35973.1 - 3.4e-18 65.0 15.4 3.8e-18 64.8 15.4 1.0 1 0 0 1 1 1 1 Ribosomal L39 protein Kinesin PF00225.23 CBZ35974.1 - 1.4e-21 76.8 0.0 1.6e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ35974.1 - 6.1e-15 55.4 0.0 6.8e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 Microtubule binding BACON PF13004.7 CBZ35974.1 - 0.08 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative binding domain, N-terminal Bac_DnaA PF00308.18 CBZ35974.1 - 0.091 12.6 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein Kinesin PF00225.23 CBZ35975.1 - 1.5e-92 310.1 0.1 1.9e-92 309.8 0.1 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ35975.1 - 5.6e-20 71.8 0.0 1.3e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding STN1_2 PF09170.10 CBZ35975.1 - 0.058 13.6 1.0 0.13 12.5 1.0 1.6 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 HR1 PF02185.16 CBZ35975.1 - 0.56 10.4 8.2 6.6 6.9 0.6 3.1 3 0 0 3 3 3 0 Hr1 repeat NIF PF03031.18 CBZ35976.1 - 1e-29 103.3 0.0 1.5e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 CBZ35976.1 - 0.00062 19.3 0.0 0.00096 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Acyltransferase PF01553.21 CBZ35977.1 - 1.9e-10 40.5 0.0 3.5e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase JmjN PF02375.17 CBZ35977.1 - 0.031 14.3 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 jmjN domain DUF5017 PF16409.5 CBZ35979.1 - 0.19 11.2 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5017) PDEase_I PF00233.19 CBZ35980.1 - 7.1e-75 251.8 2.3 7.1e-75 251.8 2.3 1.9 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Pec_lyase_N PF04431.13 CBZ35980.1 - 3.6 7.9 5.5 14 6.0 1.1 2.7 2 0 0 2 2 2 0 Pectate lyase, N terminus HSP20 PF00011.21 CBZ35981.1 - 7.2e-17 61.4 0.0 8.8e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CBZ35981.1 - 1.2e-09 37.6 0.0 4.2e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 HSP20-like domain found in ArsA PapC_N PF13954.6 CBZ35981.1 - 0.002 18.1 0.0 0.0027 17.7 0.0 1.2 1 0 0 1 1 1 1 PapC N-terminal domain Ribosomal_L13e PF01294.18 CBZ35982.1 - 1.8e-14 54.0 4.9 2e-14 53.9 4.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L13e PF01294.18 CBZ35983.1 - 5.8e-12 45.8 4.6 6.4e-12 45.7 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L13e HCV_NS5a PF01506.19 CBZ35984.1 - 9.7 6.2 9.8 10 6.1 1.4 2.3 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor Pkinase PF00069.25 CBZ35985.1 - 2.8e-42 144.9 0.0 4e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35985.1 - 5.2e-36 124.2 0.0 6.5e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ35985.1 - 0.0017 17.2 0.0 0.0037 16.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ35985.1 - 0.022 14.7 0.3 0.05 13.5 0.3 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CBZ35985.1 - 0.062 12.3 0.1 0.1 11.5 0.1 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Haspin_kinase PF12330.8 CBZ35985.1 - 0.079 11.9 0.4 0.17 10.8 0.4 1.5 1 1 0 1 1 1 0 Haspin like kinase domain CBP_BcsO PF17037.5 CBZ35985.1 - 0.093 12.9 0.1 0.15 12.2 0.1 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO AAA PF00004.29 CBZ35986.1 - 5e-40 137.0 0.0 1.2e-39 135.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CBZ35986.1 - 2.7e-24 84.9 0.1 8e-24 83.4 0.1 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CBZ35986.1 - 1.2e-16 60.5 3.0 1.2e-16 60.5 3.0 2.2 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CBZ35986.1 - 3.2e-09 36.5 0.3 1.2e-07 31.4 0.0 3.0 3 0 0 3 3 3 1 AAA+ lid domain AAA_2 PF07724.14 CBZ35986.1 - 9.8e-06 25.8 0.0 2.7e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBZ35986.1 - 1.2e-05 25.7 0.1 0.00054 20.4 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CBZ35986.1 - 2.8e-05 24.4 0.0 0.0029 17.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBZ35986.1 - 0.00013 22.0 0.0 0.00077 19.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CBZ35986.1 - 0.0006 19.6 0.0 0.0014 18.4 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 CBZ35986.1 - 0.00062 19.0 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CBZ35986.1 - 0.00071 19.4 0.0 0.002 17.9 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CBZ35986.1 - 0.0015 18.7 0.0 0.0038 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain USP8_dimer PF08969.11 CBZ35986.1 - 0.0017 18.5 3.2 0.0052 17.0 3.2 1.8 1 0 0 1 1 1 1 USP8 dimerisation domain TIP49 PF06068.13 CBZ35986.1 - 0.0021 17.4 0.0 0.0031 16.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 CBZ35986.1 - 0.0023 17.7 0.0 0.0059 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CBZ35986.1 - 0.0029 17.6 0.0 0.011 15.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 CBZ35986.1 - 0.0075 16.8 0.0 0.019 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBZ35986.1 - 0.0092 16.4 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 CBZ35986.1 - 0.011 15.3 0.2 0.9 9.1 0.1 2.4 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 CBZ35986.1 - 0.027 14.9 0.1 0.092 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CBZ35986.1 - 0.029 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CBZ35986.1 - 0.05 13.5 1.9 2.8 7.8 0.0 2.9 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 CBZ35986.1 - 0.05 13.0 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 CBZ35986.1 - 0.057 13.3 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 CBZ35986.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 CBZ35986.1 - 0.071 12.6 0.0 0.22 11.0 0.0 1.8 2 1 0 2 2 2 0 P-loop containing dynein motor region PPV_E1_C PF00519.17 CBZ35986.1 - 0.085 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase NACHT PF05729.12 CBZ35986.1 - 0.087 12.7 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AFG1_ATPase PF03969.16 CBZ35986.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase PhoH PF02562.16 CBZ35986.1 - 0.13 11.7 0.2 0.32 10.4 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 CBZ35986.1 - 0.15 11.7 0.0 0.42 10.3 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain PFK PF00365.20 CBZ35987.1 - 8.6e-63 212.3 0.1 1.1e-62 212.0 0.1 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 CBZ35987.1 - 0.00041 19.9 0.2 0.001 18.7 0.0 1.7 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 CBZ35987.1 - 0.024 13.8 0.0 0.053 12.7 0.0 1.6 1 1 0 1 1 1 0 ATP-NAD kinase zf-MIZ PF02891.20 CBZ35988.1 - 1.2e-09 37.8 0.3 1e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CBZ35988.1 - 0.042 13.7 0.3 0.1 12.4 0.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit CMV_1a PF12467.8 CBZ35988.1 - 1.5 9.1 5.2 5.3 7.4 0.3 3.3 2 1 1 3 3 3 0 Cucumber mosaic virus 1a protein family Methyltr_RsmB-F PF01189.17 CBZ35990.1 - 6e-39 133.8 0.1 1.1e-37 129.7 0.1 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CBZ35990.1 - 5.7e-05 23.3 0.0 0.00022 21.4 0.0 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 CBZ35990.1 - 0.0079 16.9 0.0 0.028 15.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 CBZ35990.1 - 0.13 12.8 0.0 0.43 11.1 0.0 2.0 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF TPR_19 PF14559.6 CBZ35991.1 - 2.2e-22 79.3 26.4 1.8e-07 31.5 0.8 8.8 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ35991.1 - 2.5e-16 59.0 37.8 0.002 18.8 0.2 10.5 9 1 2 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ35991.1 - 2.8e-13 50.3 32.1 3.2e-05 24.5 0.5 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBZ35991.1 - 4.3e-09 36.1 18.6 0.00013 21.6 1.3 5.3 5 1 1 6 6 6 3 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 CBZ35991.1 - 1.5e-07 31.6 14.3 0.18 12.0 0.2 5.9 6 0 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CBZ35991.1 - 0.00013 21.8 33.9 0.089 13.0 0.0 11.0 13 0 0 13 13 11 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ35991.1 - 0.00015 21.9 10.4 8.4 7.0 0.1 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ35991.1 - 0.00018 21.8 36.8 0.46 10.8 0.0 10.1 8 3 2 10 10 10 3 Tetratricopeptide repeat NatB_MDM20 PF09797.9 CBZ35991.1 - 0.00043 19.3 1.1 0.0048 15.9 0.2 2.4 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_4 PF07721.14 CBZ35991.1 - 0.0065 17.0 43.6 2.2 9.2 0.9 9.8 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_20 PF14561.6 CBZ35991.1 - 0.0072 16.6 6.0 0.054 13.8 0.3 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Topoisom_bac PF01131.20 CBZ35991.1 - 0.0085 15.1 0.2 0.016 14.3 0.2 1.4 1 0 0 1 1 1 1 DNA topoisomerase TPR_11 PF13414.6 CBZ35991.1 - 0.033 13.9 10.2 3.9 7.2 0.0 6.0 7 1 1 8 8 8 0 TPR repeat TPR_8 PF13181.6 CBZ35991.1 - 0.035 14.3 3.1 1.4e+02 3.1 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ35991.1 - 0.037 14.1 1.8 18 5.5 0.0 4.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CBZ35991.1 - 0.11 13.2 19.1 0.67 10.7 0.0 8.3 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ35991.1 - 0.4 10.6 0.0 0.4 10.6 0.0 7.2 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF4586 PF15239.6 CBZ35992.1 - 2.8e-66 224.8 13.7 3.4e-66 224.5 13.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Pkinase PF00069.25 CBZ35993.1 - 1.3e-64 218.1 0.0 2e-64 217.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ35993.1 - 1.6e-44 152.1 0.0 2.8e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ35993.1 - 2.8e-05 23.6 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ35993.1 - 0.019 14.9 0.1 6.4 6.6 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ35993.1 - 0.039 12.7 0.6 0.094 11.5 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase APC_u15 PF16636.5 CBZ35993.1 - 8.5 6.9 7.1 2.5 8.6 3.6 2.0 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 Nucleoporin_FG PF13634.6 CBZ35994.1 - 0.044 14.6 0.9 0.044 14.6 0.9 3.2 3 0 0 3 3 3 0 Nucleoporin FG repeat region DCX PF03607.17 CBZ35995.1 - 4.9e-06 26.5 0.0 0.00065 19.8 0.0 2.5 2 0 0 2 2 2 2 Doublecortin Msg2_C PF12373.8 CBZ35995.1 - 0.53 9.8 3.4 1.2 8.6 3.4 1.6 1 0 0 1 1 1 0 Major surface glycoprotein 2 C terminal NTP_transf_2 PF01909.23 CBZ35996.1 - 0.041 14.2 0.0 0.061 13.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase domain NACHT_N PF17100.5 CBZ35996.1 - 0.078 12.8 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase GAS PF13851.6 CBZ35997.1 - 0.43 9.9 11.8 0.026 13.9 5.3 2.4 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Rx_N PF18052.1 CBZ35997.1 - 9.4 6.6 7.2 5.6 7.3 0.5 3.7 4 1 1 5 5 5 0 Rx N-terminal domain SAM_1 PF00536.30 CBZ35999.1 - 0.0001 22.7 0.0 0.00025 21.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CBZ35999.1 - 0.089 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DnaB_bind PF10410.9 CBZ35999.1 - 0.32 11.2 3.8 5.3 7.3 0.0 4.2 4 0 0 4 4 4 0 DnaB-helicase binding domain of primase DUF2613 PF11021.8 CBZ35999.1 - 3.8 7.7 5.8 15 5.8 5.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) B12-binding_2 PF02607.17 CBZ35999.1 - 4.7 7.7 7.2 11 6.6 0.1 3.7 4 0 0 4 4 4 0 B12 binding domain FlxA PF14282.6 CBZ35999.1 - 6.7 6.8 9.3 4.8 7.2 0.3 3.9 4 0 0 4 4 4 0 FlxA-like protein SPACA9 PF15120.6 CBZ36000.1 - 0.068 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Sperm acrosome-associated protein 9 Cnd3 PF12719.7 CBZ36001.1 - 4.5e-33 114.7 0.2 4.5e-33 114.7 0.2 2.2 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 CBZ36001.1 - 1.3e-06 28.5 1.8 0.063 13.3 0.2 4.6 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ36001.1 - 2e-05 24.9 1.3 0.0012 19.2 0.1 5.3 5 1 2 7 7 7 3 HEAT repeats HEAT PF02985.22 CBZ36001.1 - 3.9e-05 23.6 10.8 1.8 9.0 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat RTP1_C1 PF10363.9 CBZ36001.1 - 0.059 13.6 0.1 1.9 8.7 0.0 3.0 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CBZ36001.1 - 1.4 9.5 4.3 13 6.4 0.1 4.2 4 0 0 4 4 4 0 HEAT-like repeat ACOX PF01756.19 CBZ36001.1 - 1.4 8.4 5.0 0.4 10.2 1.1 2.0 2 0 0 2 2 2 0 Acyl-CoA oxidase Helicase_C_2 PF13307.6 CBZ36002.1 - 1.5e-49 168.5 0.0 4.4e-49 166.9 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 CBZ36002.1 - 1.7e-43 148.3 0.2 1.6e-42 145.1 0.0 2.1 2 0 0 2 2 2 1 DEAD_2 DEAD PF00270.29 CBZ36002.1 - 0.00013 21.8 0.0 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CBZ36002.1 - 0.0002 21.4 0.0 0.016 15.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HBB PF06777.11 CBZ36002.1 - 0.0023 17.6 0.0 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 Helical and beta-bridge domain AAA_11 PF13086.6 CBZ36002.1 - 0.041 13.7 0.6 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 CBZ36003.1 - 2.7e-63 213.8 0.0 3.6e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36003.1 - 1.8e-40 138.9 0.0 2.4e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ36003.1 - 0.00027 19.9 0.0 0.00067 18.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ36003.1 - 0.00075 19.5 0.2 0.26 11.2 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ36003.1 - 0.0012 18.3 0.0 0.0029 17.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CBZ36003.1 - 0.015 14.9 0.0 0.46 10.1 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CBZ36003.1 - 0.079 11.9 0.1 10 5.0 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain PDEase_I PF00233.19 CBZ36004.1 - 3.3e-47 161.2 0.8 1.3e-46 159.3 0.0 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase FYVE PF01363.21 CBZ36004.1 - 5.8e-08 32.8 12.3 1.5e-07 31.5 12.3 1.7 1 0 0 1 1 1 1 FYVE zinc finger Beta_helix PF13229.6 CBZ36007.1 - 3.7e-31 108.1 1.9 4.4e-16 59.1 0.1 2.1 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 CBZ36007.1 - 2.5e-10 40.1 0.0 3.4e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 CBZ36007.1 - 0.039 13.8 0.1 0.67 9.8 0.0 2.1 1 1 0 2 2 2 0 Pectate lyase superfamily protein Pkinase PF00069.25 CBZ36008.1 - 4.9e-38 131.0 0.0 1.5e-36 126.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36008.1 - 4.1e-16 59.0 0.0 5.9e-16 58.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBZ36008.1 - 9.5e-05 21.8 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FAM47 PF14642.6 CBZ36008.1 - 0.033 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 FAM47 family YrbL-PhoP_reg PF10707.9 CBZ36008.1 - 0.2 11.1 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL START PF01852.19 CBZ36009.1 - 4.3e-27 94.9 0.0 9.7e-27 93.7 0.0 1.5 2 0 0 2 2 2 1 START domain Actin PF00022.19 CBZ36010.1 - 8.4e-19 67.4 0.0 4.5e-13 48.6 0.0 2.2 2 0 0 2 2 2 2 Actin Pet100 PF09803.9 CBZ36011.1 - 0.14 12.7 0.0 0.37 11.3 0.0 1.6 2 0 0 2 2 2 0 Pet100 TPR_19 PF14559.6 CBZ36012.1 - 2.2e-10 40.9 3.2 0.0037 17.7 0.1 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ36012.1 - 8.3e-09 36.0 1.4 0.35 11.5 0.0 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ36012.1 - 9.6e-08 31.6 21.0 0.053 13.7 0.0 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ36012.1 - 0.00014 22.0 19.8 0.38 11.0 1.8 5.3 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CBZ36012.1 - 0.00097 18.9 16.6 0.15 11.9 0.3 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ36012.1 - 0.0016 19.1 6.9 22 6.2 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ36012.1 - 0.003 17.8 8.6 2.2 8.6 0.2 5.2 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ36012.1 - 0.0086 15.7 0.9 3.2 7.5 0.0 2.9 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.6 CBZ36012.1 - 0.094 12.8 2.9 2 8.7 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ36012.1 - 0.39 11.0 14.6 3.5 8.1 0.1 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ36012.1 - 0.94 10.3 11.2 5.6 7.8 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Trypsin_2 PF13365.6 CBZ36013.1 - 0.0057 17.6 3.7 0.021 15.7 3.7 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Mito_carr PF00153.27 CBZ36014.1 - 5.5e-58 192.9 0.8 1.3e-19 69.8 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein ThrE_2 PF12821.7 CBZ36014.1 - 0.0035 17.5 1.4 0.088 12.9 0.2 2.5 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE Acyl_transf_3 PF01757.22 CBZ36015.1 - 0.041 12.9 1.3 0.049 12.7 1.3 1.1 1 0 0 1 1 1 0 Acyltransferase family IU_nuc_hydro PF01156.19 CBZ36016.1 - 2.3e-43 148.9 0.0 3e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LRR_6 PF13516.6 CBZ36017.1 - 2.5e-34 114.4 39.0 0.00055 19.8 0.1 13.5 14 0 0 14 14 14 11 Leucine Rich repeat LRR_1 PF00560.33 CBZ36017.1 - 1.5e-11 43.1 5.2 19 6.3 0.0 10.2 11 0 0 11 11 10 0 Leucine Rich Repeat LRR_4 PF12799.7 CBZ36017.1 - 1.2e-07 31.9 13.5 0.72 10.4 0.0 6.9 7 0 0 7 7 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ36017.1 - 0.0041 16.9 23.7 4 7.3 1.5 7.8 5 4 0 5 5 5 2 Leucine rich repeat PIEZO PF15917.5 CBZ36017.1 - 0.25 10.8 3.1 0.55 9.7 3.1 1.5 1 0 0 1 1 1 0 Piezo GIT_CC PF16559.5 CBZ36017.1 - 0.98 9.3 3.7 1.4 8.9 1.5 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 CBZ36017.1 - 2.6 7.3 12.4 5.8 6.2 12.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 CBZ36017.1 - 3 7.9 7.8 6.4 6.8 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 CBZ36017.1 - 3 8.6 6.4 2.4 9.0 3.9 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF3450 PF11932.8 CBZ36017.1 - 3.1 7.0 13.4 2.5 7.3 6.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FAM76 PF16046.5 CBZ36017.1 - 5.8 6.2 7.1 10 5.3 7.1 1.4 1 0 0 1 1 1 0 FAM76 protein RRM_1 PF00076.22 CBZ36019.1 - 2.4e-18 65.7 0.0 3.5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ36019.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrolase_4 PF12146.8 CBZ36024.1 - 4.1e-09 36.1 0.0 7.6e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ36024.1 - 1.5e-08 34.6 0.1 3.9e-07 30.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBZ36024.1 - 1.6e-07 32.1 2.5 1.6e-07 32.1 2.5 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Pro_isomerase PF00160.21 CBZ36025.1 - 1.4e-19 71.0 0.0 2e-18 67.1 0.0 2.0 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UPF0220 PF05255.11 CBZ36027.1 - 8.6e-17 61.2 0.1 1e-16 60.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3267 PF11667.8 CBZ36027.1 - 0.0037 17.5 0.3 0.0084 16.4 0.1 1.7 1 1 1 2 2 2 1 Putative zincin peptidase BacA PF02673.18 CBZ36027.1 - 0.022 14.5 0.2 0.032 13.9 0.2 1.3 1 1 0 1 1 1 0 Bacitracin resistance protein BacA DUF5391 PF17369.2 CBZ36027.1 - 0.087 12.9 2.8 0.17 11.9 2.8 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5391) MATH PF00917.26 CBZ36028.1 - 3.1e-06 27.3 0.3 3.1e-06 27.3 0.3 2.3 2 0 0 2 2 2 1 MATH domain YL1 PF05764.13 CBZ36028.1 - 0.0042 17.2 7.7 0.0042 17.2 7.7 2.5 2 0 0 2 2 2 1 YL1 nuclear protein CorA PF01544.18 CBZ36028.1 - 0.29 10.4 14.2 0.71 9.1 14.2 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein REF PF05755.12 CBZ36028.1 - 8.6 6.1 10.6 83 2.9 10.6 2.3 1 1 0 1 1 1 0 Rubber elongation factor protein (REF) Phycoerythr_ab PF02972.14 CBZ36030.1 - 0.19 11.6 0.2 2.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Phycoerythrin, alpha/beta chain Cyclin_N PF00134.23 CBZ36031.1 - 5.4e-24 84.4 0.2 1.6e-23 82.8 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TERF2_RBM PF16772.5 CBZ36031.1 - 0.14 11.6 0.0 0.44 10.0 0.0 1.8 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif eIF-3_zeta PF05091.12 CBZ36032.1 - 5.1 6.0 10.4 5.8 5.8 10.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RseC_MucC PF04246.12 CBZ36033.1 - 0.088 12.8 0.2 0.21 11.5 0.2 1.6 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC WD40_3 PF15911.5 CBZ36033.1 - 0.1 12.6 0.0 2.4 8.2 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat AAA_25 PF13481.6 CBZ36033.1 - 0.13 11.9 0.1 0.46 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PQQ_2 PF13360.6 CBZ36033.1 - 0.17 11.4 2.8 4 6.9 1.0 2.9 2 0 0 2 2 2 0 PQQ-like domain LRR_4 PF12799.7 CBZ36034.1 - 5.7e-08 32.9 7.6 0.00016 22.0 0.2 4.8 5 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ36034.1 - 2.6e-05 23.9 7.1 0.015 15.0 0.1 4.5 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.6 CBZ36034.1 - 0.096 12.8 5.5 30 5.0 0.1 4.8 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ36034.1 - 5.1 8.0 7.0 43 5.2 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich Repeat FAD-oxidase_C PF02913.19 CBZ36035.1 - 3.5e-48 164.4 0.0 6.2e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CBZ36035.1 - 1.4e-37 128.5 0.0 2.4e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CBZ36035.1 - 0.015 15.4 0.0 0.041 14.0 0.0 1.8 2 0 0 2 2 2 0 Berberine and berberine like tRNA-synt_2 PF00152.20 CBZ36036.1 - 3.9e-78 262.7 0.0 4.9e-78 262.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CBZ36036.1 - 1.6e-09 37.6 0.1 0.00026 20.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 CBZ36036.1 - 2.6e-07 30.5 0.0 4.6e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Yip1 PF04893.17 CBZ36037.1 - 6.9e-10 38.9 17.1 1.2e-09 38.1 16.6 1.5 1 1 0 1 1 1 1 Yip1 domain LRR_6 PF13516.6 CBZ36038.1 - 1.1e-28 96.8 4.4 1e-06 28.3 0.1 5.3 5 0 0 5 5 5 5 Leucine Rich repeat LRR_4 PF12799.7 CBZ36038.1 - 4.6e-07 30.0 1.1 0.00037 20.8 0.1 3.2 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ36038.1 - 2.1e-05 24.4 0.0 0.61 10.9 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_8 PF13855.6 CBZ36038.1 - 0.0001 22.0 1.1 0.041 13.7 1.5 3.8 2 2 0 2 2 2 1 Leucine rich repeat Lgl_C PF08596.10 CBZ36038.1 - 0.0088 14.8 0.1 1 8.0 0.0 2.1 2 0 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal Rubis-subs-bind PF09273.11 CBZ36039.1 - 9.2e-11 42.5 0.0 3.4e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 CBZ36039.1 - 0.039 14.4 0.0 0.065 13.6 0.0 1.6 1 1 0 1 1 1 0 SET domain T6SS_TssG PF06996.11 CBZ36039.1 - 0.084 12.1 0.2 0.58 9.3 0.1 2.0 2 0 0 2 2 2 0 Type VI secretion, TssG NAD_binding_2 PF03446.15 CBZ36040.1 - 5.9e-50 169.5 0.4 1e-49 168.7 0.4 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CBZ36040.1 - 6.8e-36 123.2 0.2 1.1e-35 122.5 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 CBZ36040.1 - 3.7e-05 23.2 0.2 0.00015 21.2 0.0 2.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CBZ36040.1 - 0.00073 20.1 1.8 0.0017 18.9 0.0 2.5 4 0 0 4 4 4 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CBZ36040.1 - 0.0034 17.5 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CBZ36040.1 - 0.0038 17.1 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 CBZ36040.1 - 0.03 13.9 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain PDH PF02153.17 CBZ36040.1 - 0.031 13.3 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase ApbA PF02558.16 CBZ36040.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CBZ36040.1 - 0.083 12.5 0.1 12 5.4 0.0 2.3 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gly-zipper_Omp PF13488.6 CBZ36043.1 - 0.14 12.2 7.1 0.23 11.5 7.1 1.4 1 0 0 1 1 1 0 Glycine zipper DUF4781 PF16013.5 CBZ36043.1 - 0.26 10.1 0.3 0.29 9.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) RrnaAD PF00398.20 CBZ36044.1 - 3.6e-61 206.6 0.0 5.1e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CBZ36044.1 - 1.3e-07 32.3 0.0 2.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ36044.1 - 3.1e-05 24.6 0.0 6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ36044.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ36044.1 - 0.0015 19.2 0.0 0.003 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CBZ36044.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.17 CBZ36044.1 - 0.048 13.3 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 CBZ36044.1 - 0.049 13.4 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.12 CBZ36044.1 - 0.067 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 CBZ36044.1 - 0.083 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 CBZ36044.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CBZ36044.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_18 PF12847.7 CBZ36044.1 - 0.15 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain zf-RanBP PF00641.18 CBZ36045.1 - 0.005 16.1 1.6 0.005 16.1 1.6 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others VHS PF00790.19 CBZ36045.1 - 0.081 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 VHS domain Mito_carr PF00153.27 CBZ36046.1 - 5.2e-12 45.5 0.1 4.6e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein Tim17 PF02466.19 CBZ36046.1 - 0.041 14.3 0.3 0.13 12.7 0.1 2.0 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family RNase_T PF00929.24 CBZ36048.1 - 1.4e-16 61.4 0.0 3.4e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH_1 PF13423.6 CBZ36048.1 - 4e-13 49.7 0.0 2.5e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 CBZ36048.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2_4 PF13894.6 CBZ36049.1 - 2.2e-15 56.0 49.8 0.005 17.6 0.5 8.4 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2 PF00096.26 CBZ36049.1 - 6.2e-12 45.3 47.1 0.049 14.1 1.0 8.3 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-met PF12874.7 CBZ36049.1 - 8.8e-09 35.5 10.5 0.0039 17.5 0.7 5.7 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CBZ36049.1 - 4.2e-07 30.2 32.4 0.0012 19.1 2.4 7.0 7 0 0 7 7 7 3 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CBZ36049.1 - 1.6e-06 28.3 15.6 0.03 14.6 0.1 5.4 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding Actin_micro PF17003.5 CBZ36049.1 - 0.00011 21.6 7.2 0.22 10.7 0.0 4.9 5 0 0 5 5 5 2 Putative actin-like family RNA_POL_M_15KD PF02150.16 CBZ36049.1 - 0.016 15.0 0.4 0.016 15.0 0.4 2.6 3 0 0 3 3 2 0 RNA polymerases M/15 Kd subunit DUF4729 PF15866.5 CBZ36049.1 - 0.028 13.8 10.9 2 7.7 1.2 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4729) DUF629 PF04780.12 CBZ36049.1 - 0.062 11.8 16.3 0.44 9.0 0.2 5.2 5 1 1 6 6 6 0 Protein of unknown function (DUF629) TRAF6_Z2 PF18048.1 CBZ36049.1 - 0.21 11.7 3.7 7.3 6.8 0.0 3.7 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 zf-met2 PF12907.7 CBZ36049.1 - 0.22 11.7 12.7 2.2 8.5 0.3 4.7 5 1 0 5 5 5 0 Zinc-binding HypA PF01155.19 CBZ36049.1 - 0.66 10.0 11.0 0.94 9.5 0.2 4.1 2 2 2 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_3rep PF18868.1 CBZ36049.1 - 0.74 10.5 19.8 0.78 10.4 0.4 5.5 4 2 1 6 6 6 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 CBZ36049.1 - 1.2 8.9 12.2 2.8 7.8 0.2 4.5 4 0 0 4 4 4 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CBZ36049.1 - 1.4 9.3 22.8 2.7 8.4 0.4 6.3 5 1 2 7 7 7 0 C2H2 type zinc-finger (2 copies) zf_C2H2_10 PF18414.1 CBZ36049.1 - 8.5 6.0 10.6 5.6 6.6 0.1 3.4 4 0 0 4 4 3 0 C2H2 type zinc-finger Peptidase_C54 PF03416.19 CBZ36050.1 - 5.7e-45 153.9 0.0 1.3e-44 152.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 CBZ36050.1 - 0.054 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase family C78 COP23 PF14218.6 CBZ36050.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.5 1 0 0 1 1 1 0 Circadian oscillating protein COP23 LIM PF00412.22 CBZ36051.1 - 3.6e-05 23.9 11.6 4.6e-05 23.6 8.6 2.4 2 1 0 2 2 2 1 LIM domain NCD3G PF07562.14 CBZ36051.1 - 0.085 12.8 4.9 4.2 7.4 1.3 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DUF3022 PF11226.8 CBZ36052.1 - 0.062 13.7 2.5 0.37 11.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3022) TNFR_c6 PF00020.18 CBZ36052.1 - 3.7 8.0 7.1 5.2 7.6 0.3 2.8 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region Sad1_UNC PF07738.13 CBZ36055.1 - 2.4e-19 69.6 0.0 3.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Ku PF02735.16 CBZ36056.1 - 1.8e-29 102.9 0.0 3.2e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 CBZ36056.1 - 2.2e-22 79.4 0.1 6.3e-22 78.0 0.0 1.8 2 0 0 2 2 2 1 Ku C terminal domain like Ku_N PF03731.15 CBZ36056.1 - 2.9e-07 30.4 0.0 6.6e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.6 CBZ36056.1 - 0.018 15.7 0.0 2.7 8.7 0.0 2.9 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA PF00092.28 CBZ36056.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Kinesin PF00225.23 CBZ36057.1 - 1.4e-89 300.4 1.4 2.1e-89 299.7 1.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ36057.1 - 2.9e-26 92.2 0.1 1.1e-25 90.3 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding AAA_16 PF13191.6 CBZ36057.1 - 0.0058 17.0 0.8 0.026 14.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ36057.1 - 0.0086 16.4 0.1 0.22 11.8 0.0 3.0 2 1 1 3 3 3 1 AAA domain YabA PF06156.13 CBZ36057.1 - 0.011 16.3 4.0 0.073 13.7 4.0 2.5 1 1 0 1 1 1 0 Initiation control protein YabA PIF1 PF05970.14 CBZ36057.1 - 0.026 13.7 0.2 0.083 12.0 0.2 1.8 1 0 0 1 1 1 0 PIF1-like helicase bZIP_1 PF00170.21 CBZ36057.1 - 0.027 14.5 1.9 0.027 14.5 1.9 2.7 2 0 0 2 2 2 0 bZIP transcription factor TSC22 PF01166.18 CBZ36057.1 - 0.03 14.6 0.6 0.11 12.8 0.6 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family Cast PF10174.9 CBZ36057.1 - 0.037 12.3 12.5 0.0077 14.5 9.1 1.5 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone AAA_19 PF13245.6 CBZ36057.1 - 0.1 12.9 4.0 6.2 7.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain TMF_DNA_bd PF12329.8 CBZ36057.1 - 0.27 11.3 10.0 0.57 10.2 0.5 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding USP8_interact PF08941.10 CBZ36057.1 - 3 7.6 5.6 12 5.7 1.4 2.5 2 0 0 2 2 2 0 USP8 interacting DUF5082 PF16888.5 CBZ36057.1 - 6.4 7.1 9.1 10 6.4 0.3 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 CBZ36057.1 - 9.2 5.5 12.7 0.41 10.0 4.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) EMP70 PF02990.16 CBZ36058.1 - 7.5e-145 483.5 8.8 1e-144 483.1 8.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Pkinase PF00069.25 CBZ36059.1 - 1.3e-60 205.0 0.0 7e-60 202.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36059.1 - 2.5e-26 92.5 0.0 3.9e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ36059.1 - 0.00015 21.2 0.0 0.00048 19.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like DUF3455 PF11937.8 CBZ36059.1 - 0.088 13.2 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3455) Seadorna_VP7 PF07387.11 CBZ36059.1 - 0.2 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 PP2C PF00481.21 CBZ36060.1 - 1e-47 163.0 0.1 1.4e-47 162.6 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ36060.1 - 0.00019 21.2 0.1 0.00096 18.8 0.1 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CBZ36060.1 - 0.00021 21.3 0.0 0.00085 19.3 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Hydrolase_4 PF12146.8 CBZ36062.1 - 2.7e-12 46.5 0.0 1.5e-09 37.5 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ36062.1 - 8.4e-09 35.4 0.1 9.6e-06 25.4 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CBZ36062.1 - 2.2e-08 34.0 0.0 1.4e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 CBZ36062.1 - 0.00069 20.3 0.1 0.00069 20.3 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBZ36062.1 - 0.00089 18.8 0.0 0.013 15.0 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 CBZ36062.1 - 0.016 14.8 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase PAP2 PF01569.21 CBZ36063.1 - 1.1e-23 83.5 5.1 1.8e-23 82.8 5.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily ODAM PF15424.6 CBZ36063.1 - 0.038 13.6 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family Ribosomal_L12_N PF16320.5 CBZ36063.1 - 0.13 12.0 0.1 4.5 7.1 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain WD40 PF00400.32 CBZ36064.1 - 5.2e-30 103.0 14.1 5e-09 36.6 0.5 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ36064.1 - 3.1e-16 59.4 0.2 5.8e-05 23.3 0.0 5.4 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ36064.1 - 0.00038 19.5 0.0 0.032 13.2 0.0 2.7 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DAGK_cat PF00781.24 CBZ36065.1 - 1.2e-13 50.8 0.0 2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PFK PF00365.20 CBZ36065.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphofructokinase Evr1_Alr PF04777.13 CBZ36066.1 - 2.2e-12 47.3 0.1 8.9e-12 45.4 0.0 2.2 2 1 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 CBZ36066.1 - 2.2e-07 30.8 0.0 5.6e-07 29.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin RRF PF01765.19 CBZ36067.1 - 4.3e-16 59.3 2.5 4.3e-16 59.3 2.5 1.8 1 1 1 2 2 2 1 Ribosome recycling factor Nab2 PF11517.8 CBZ36067.1 - 0.067 13.5 1.0 0.43 10.9 0.1 2.5 1 1 1 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) DUF2203 PF09969.9 CBZ36067.1 - 3.3 8.4 5.6 1.2 9.8 0.8 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) IF4E PF01652.18 CBZ36068.1 - 2e-27 95.9 0.0 2.7e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E tRNA-synt_2 PF00152.20 CBZ36069.1 - 1.4e-74 251.0 0.0 2.1e-74 250.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CBZ36069.1 - 1.9e-09 37.4 0.1 3.6e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CBZ36069.1 - 8.8e-05 22.1 0.2 0.25 10.8 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Retinal PF15449.6 CBZ36070.1 - 9.2 3.9 11.5 13 3.4 11.5 1.1 1 0 0 1 1 1 0 Retinal protein Bystin PF05291.11 CBZ36071.1 - 8.6e-110 366.6 0.3 1.2e-109 366.2 0.3 1.1 1 0 0 1 1 1 1 Bystin DUF3299 PF11736.8 CBZ36071.1 - 0.027 14.5 0.4 0.067 13.2 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3299) GPHR_N PF12537.8 CBZ36072.1 - 1.7 8.8 4.4 28 4.9 0.3 3.2 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Macoilin PF09726.9 CBZ36072.1 - 3 6.3 16.4 9.3 4.7 16.5 1.5 1 1 0 1 1 1 0 Macoilin family Med9 PF07544.13 CBZ36072.1 - 7.6 6.7 21.9 4.4 7.5 8.7 3.8 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4611 PF15387.6 CBZ36074.1 - 0.00078 19.6 1.6 0.0019 18.4 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 CBZ36074.1 - 0.24 11.8 4.6 0.76 10.2 4.6 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 CBZ36074.1 - 0.34 11.0 14.5 0.15 12.2 5.7 2.2 2 0 0 2 2 2 0 YL1 nuclear protein CDC45 PF02724.14 CBZ36074.1 - 0.68 8.1 3.4 0.94 7.7 3.4 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 CBZ36074.1 - 5.5 6.6 7.2 0.31 10.7 1.8 1.7 2 0 0 2 2 2 0 FAM176 family DUF3246 PF11596.8 CBZ36074.1 - 5.9 6.2 15.2 0.086 12.3 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) BUD22 PF09073.10 CBZ36074.1 - 7.1 5.8 14.8 0.28 10.5 8.3 1.8 2 0 0 2 2 2 0 BUD22 NOA36 PF06524.12 CBZ36074.1 - 7.9 5.7 7.4 12 5.1 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein LRR_4 PF12799.7 CBZ36075.1 - 2.3e-06 27.8 0.2 0.02 15.3 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ36075.1 - 0.011 15.5 1.0 0.056 13.2 0.3 2.1 2 1 0 2 2 2 0 Leucine rich repeat LRR_9 PF14580.6 CBZ36075.1 - 0.066 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat NatB_MDM20 PF09797.9 CBZ36076.1 - 2.8e-27 95.7 0.1 5e-26 91.5 0.0 2.2 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 CBZ36076.1 - 0.16 12.5 15.3 0.073 13.6 1.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ36076.1 - 5.1 7.8 11.2 0.72 10.6 1.2 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Alg14 PF08660.11 CBZ36077.1 - 1.3e-57 194.6 0.0 1.9e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.16 CBZ36077.1 - 7.3e-19 68.4 0.0 2e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain RRM_1 PF00076.22 CBZ36078.1 - 5.5e-15 55.0 0.0 8.5e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LMBR1 PF04791.16 CBZ36079.1 - 3.5e-54 184.6 21.5 4.6e-54 184.2 21.5 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein FKBP_N PF01346.18 CBZ36080.1 - 0.15 13.0 0.3 0.15 13.0 0.3 4.0 3 2 0 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF3037 PF11236.8 CBZ36080.1 - 0.82 10.1 6.4 1.6 9.2 1.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) CTP_transf_like PF01467.26 CBZ36080.1 - 0.86 9.8 2.8 2 8.6 2.8 1.8 1 1 0 1 1 1 0 Cytidylyltransferase-like PSP PF04046.16 CBZ36081.1 - 1e-18 66.9 3.0 2.8e-18 65.5 3.0 1.8 1 0 0 1 1 1 1 PSP DUF382 PF04037.13 CBZ36081.1 - 3.8e-11 43.2 3.3 6.2e-11 42.5 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF382) LUC7 PF03194.15 CBZ36081.1 - 0.086 12.5 10.3 0.12 12.0 10.3 1.1 1 0 0 1 1 1 0 LUC7 N_terminus AMP-binding PF00501.28 CBZ36082.1 - 9.7e-26 90.3 0.0 4.5e-12 45.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme BBS2_C PF14782.6 CBZ36083.1 - 6.4e-126 420.6 0.0 8.9e-126 420.1 0.0 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 CBZ36083.1 - 7.8e-23 80.6 0.0 8.3e-22 77.3 0.0 2.8 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 CBZ36083.1 - 3.2e-19 68.8 0.0 9.2e-19 67.3 0.0 1.8 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal FG-GAP PF01839.23 CBZ36083.1 - 0.00061 19.9 0.5 0.0018 18.3 0.5 1.8 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.6 CBZ36083.1 - 0.0078 16.8 0.5 0.031 14.9 0.1 2.3 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FlgN PF05130.12 CBZ36083.1 - 0.026 15.0 1.8 0.026 15.0 1.8 2.4 2 1 1 3 3 3 0 FlgN protein DUF4611 PF15387.6 CBZ36083.1 - 0.18 12.0 0.1 6.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Pkinase PF00069.25 CBZ36084.1 - 4.5e-65 219.6 0.0 5.8e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36084.1 - 1e-40 139.7 0.0 1.5e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ36084.1 - 0.00015 21.2 0.0 0.00096 18.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ36084.1 - 0.0092 14.8 0.0 0.035 12.9 0.0 1.9 1 1 1 2 2 2 1 Fungal protein kinase Cyt-b5 PF00173.28 CBZ36085.1 - 4.3e-24 84.4 0.0 1.4e-15 57.1 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 CBZ36085.1 - 1.7e-08 35.0 0.0 7.7e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBZ36085.1 - 1.8e-08 34.7 0.0 3.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBZ36085.1 - 5.3e-07 29.9 0.0 0.0002 21.5 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain RRS1 PF04939.12 CBZ36086.1 - 2.9e-40 137.8 5.5 2.9e-40 137.8 5.5 1.6 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) EMC3_TMCO1 PF01956.16 CBZ36086.1 - 2 8.2 5.5 4 7.2 5.5 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like tRNA-synt_His PF13393.6 CBZ36087.1 - 4.9e-36 124.6 0.0 7.1e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CBZ36087.1 - 1e-06 28.8 0.3 3.8e-06 27.0 0.0 2.0 2 1 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CBZ36087.1 - 4.1e-05 23.6 0.0 7.3e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1965 PF09248.10 CBZ36089.1 - 0.06 13.1 0.2 0.18 11.6 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) CedA PF10729.9 CBZ36089.1 - 0.079 12.8 0.5 0.29 11.0 0.0 2.2 3 0 0 3 3 3 0 Cell division activator CedA PDZ_2 PF13180.6 CBZ36090.1 - 6.9e-11 42.3 0.0 4e-10 39.9 0.1 2.2 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CBZ36090.1 - 8.3e-08 32.0 0.0 2.5e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBZ36090.1 - 2.8e-06 27.6 0.1 1e-05 25.8 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PI-PLC-X PF00388.19 CBZ36090.1 - 4.7e-06 26.2 0.0 8.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.11 CBZ36090.1 - 0.052 14.0 0.1 0.12 12.9 0.1 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like PI-PLC-Y PF00387.19 CBZ36090.1 - 0.075 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, Y domain Ribosomal_S30 PF04758.14 CBZ36091.1 - 4.7e-26 90.7 8.5 5.4e-26 90.6 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Ribosomal_S30 PF04758.14 CBZ36092.1 - 4.7e-26 90.7 8.5 5.4e-26 90.6 8.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 CS PF04969.16 CBZ36093.1 - 4e-16 59.8 0.0 6.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 CBZ36095.1 - 5.7e-26 88.5 17.5 0.00073 19.5 0.4 9.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ36095.1 - 6.4e-24 82.7 14.4 3.8e-05 23.3 0.3 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ36095.1 - 2.2e-20 71.1 10.0 9e-05 22.4 0.1 7.7 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ36095.1 - 3.7e-17 62.4 12.2 7.4e-09 35.8 0.3 6.3 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ36095.1 - 3.4e-15 56.3 1.4 0.00037 21.0 0.1 6.2 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ36095.1 - 3.5e-15 54.8 9.5 0.00056 19.8 0.2 7.2 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ36095.1 - 2.2e-13 50.6 6.3 0.0013 19.3 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ36095.1 - 1.8e-11 43.8 11.2 0.87 10.6 0.1 8.9 7 2 3 10 10 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ36095.1 - 9.9e-10 38.5 20.8 7.5e-05 22.9 0.3 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBZ36095.1 - 1.5e-08 34.8 12.1 0.0024 18.4 0.7 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ36095.1 - 1.5e-07 30.9 7.4 0.016 14.9 0.2 6.1 5 2 2 7 7 6 2 TPR repeat TPR_15 PF13429.6 CBZ36095.1 - 2.6e-06 26.9 1.4 0.022 14.0 0.0 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ36095.1 - 6e-05 23.1 3.2 0.036 14.2 0.0 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ36095.1 - 6.4e-05 23.1 8.6 9.8 6.8 0.0 6.7 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ36095.1 - 0.0021 17.9 9.4 0.98 9.4 0.5 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat SNAP PF14938.6 CBZ36095.1 - 0.0025 17.3 2.3 0.0025 17.3 2.3 2.8 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP Sel1 PF08238.12 CBZ36095.1 - 0.0029 18.2 6.7 8.5 7.2 0.0 4.8 4 0 0 4 4 4 0 Sel1 repeat BTAD PF03704.17 CBZ36095.1 - 0.021 15.2 11.5 0.72 10.3 0.2 4.6 4 2 1 5 5 5 0 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 CBZ36095.1 - 0.028 14.9 0.3 17 5.9 0.0 3.5 3 1 1 4 4 3 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 CBZ36095.1 - 0.033 14.3 13.4 3.7 7.7 0.1 6.1 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 CBZ36095.1 - 0.04 14.5 0.6 61 4.7 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 CBZ36095.1 - 0.082 13.0 1.8 0.63 10.1 0.2 2.9 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) GrpE PF01025.19 CBZ36097.1 - 2.2e-42 144.5 3.2 2.8e-42 144.2 3.2 1.2 1 0 0 1 1 1 1 GrpE Met_gamma_lyase PF06838.11 CBZ36097.1 - 0.13 10.8 0.1 0.15 10.5 0.1 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase GrpE PF01025.19 CBZ36098.1 - 1.1e-34 119.6 1.1 1.3e-34 119.3 1.1 1.0 1 0 0 1 1 1 1 GrpE BALF1 PF06861.11 CBZ36098.1 - 0.025 14.2 0.1 0.035 13.7 0.1 1.2 1 0 0 1 1 1 0 BALF1 protein DUF1192 PF06698.11 CBZ36098.1 - 0.39 10.8 2.3 3.3 7.8 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DJ-1_PfpI PF01965.24 CBZ36101.1 - 3.7e-38 130.9 0.3 4.3e-38 130.7 0.3 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family Arm PF00514.23 CBZ36102.1 - 4e-21 74.3 19.0 0.01 15.9 0.0 11.7 12 0 0 12 12 12 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CBZ36102.1 - 6.1e-18 64.7 12.3 0.002 18.1 0.0 8.6 3 3 5 9 9 9 6 Spinocerebellar ataxia type 10 protein domain HEAT_2 PF13646.6 CBZ36102.1 - 5.2e-07 30.0 7.1 0.0055 17.1 0.3 5.0 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 CBZ36102.1 - 0.00015 22.2 10.9 0.83 10.2 0.4 5.8 4 3 0 4 4 4 3 HEAT-like repeat DOG1 PF14144.6 CBZ36102.1 - 0.0086 16.3 1.4 1.2 9.4 0.0 3.6 3 0 0 3 3 3 1 Seed dormancy control Pkinase PF00069.25 CBZ36106.1 - 4e-70 236.2 0.0 7.3e-70 235.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36106.1 - 2.2e-31 109.1 0.0 3.5e-31 108.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBZ36106.1 - 5.2e-06 26.9 0.1 1.4e-05 25.5 0.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CBZ36106.1 - 0.00019 20.9 0.0 0.00048 19.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ36106.1 - 0.024 14.6 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CBZ36106.1 - 0.032 13.6 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GH97_C PF14509.6 CBZ36106.1 - 0.079 13.2 0.1 0.49 10.7 0.0 2.3 3 0 0 3 3 3 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation BCL_N PF04714.13 CBZ36106.1 - 0.12 12.5 0.1 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region FeoB_C PF07664.12 CBZ36107.1 - 0.015 14.9 0.7 0.044 13.5 0.7 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B C terminus FlaG PF03646.15 CBZ36107.1 - 0.17 12.0 0.1 0.29 11.3 0.1 1.3 1 0 0 1 1 1 0 FlaG protein CrgA PF06781.12 CBZ36108.1 - 0.17 11.9 0.3 0.37 10.9 0.3 1.6 1 0 0 1 1 1 0 Cell division protein CrgA HRG PF16954.5 CBZ36108.1 - 3.3 8.2 9.6 0.15 12.5 1.9 2.4 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Methyltransf_PK PF05891.12 CBZ36109.1 - 4e-66 222.7 0.0 4.9e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CBZ36109.1 - 9.5e-12 45.5 0.0 1.5e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ36109.1 - 3.9e-11 43.5 0.0 5.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ36109.1 - 3.3e-06 27.1 0.0 6.5e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ36109.1 - 1.9e-05 25.3 0.0 3.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ36109.1 - 5e-05 23.1 0.0 8.9e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CBZ36109.1 - 0.00011 21.7 0.0 0.0002 20.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CBZ36109.1 - 0.0002 20.7 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain DUF4407 PF14362.6 CBZ36110.1 - 0.0087 15.5 0.8 0.0087 15.5 0.8 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 CBZ36110.1 - 1.6 8.9 10.0 0.25 11.5 4.3 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF29 PF01724.16 CBZ36110.1 - 6.6 7.0 8.9 0.29 11.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF29 Prefoldin_2 PF01920.20 CBZ36111.1 - 9.6e-08 31.9 1.6 9.6e-08 31.9 1.6 1.7 1 1 0 1 1 1 1 Prefoldin subunit DUF2642 PF10842.8 CBZ36111.1 - 0.03 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2642) UPF0242 PF06785.11 CBZ36111.1 - 0.046 13.8 4.2 0.059 13.5 4.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MMR_HSR1 PF01926.23 CBZ36112.1 - 5.6e-07 29.6 0.0 0.00016 21.7 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CBZ36112.1 - 0.00014 21.7 0.0 0.0023 17.8 0.0 2.5 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CBZ36112.1 - 0.00033 20.3 0.0 0.00065 19.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CBZ36112.1 - 0.00093 18.8 0.3 0.61 9.6 0.1 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B Dynamin_N PF00350.23 CBZ36112.1 - 0.00098 19.2 0.0 0.063 13.3 0.0 2.7 2 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 CBZ36112.1 - 0.016 15.1 0.0 0.39 10.6 0.0 3.0 2 1 0 2 2 2 0 RsgA GTPase Amastin PF07344.11 CBZ36113.1 - 2.7e-44 150.7 8.7 3.2e-44 150.5 8.7 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ36114.1 - 1.8e-40 138.3 5.2 2.4e-40 137.9 5.2 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Yip1 PF04893.17 CBZ36114.1 - 0.094 12.4 11.2 0.057 13.1 8.0 1.9 2 0 0 2 2 2 0 Yip1 domain Claudin_2 PF13903.6 CBZ36114.1 - 0.17 11.6 11.1 0.071 12.8 7.1 2.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TNFR_16_TM PF18422.1 CBZ36114.1 - 0.31 11.0 2.3 9.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Ycf66_N PF07444.11 CBZ36114.1 - 0.81 9.9 7.0 0.17 12.0 1.5 2.4 3 0 0 3 3 3 0 Ycf66 protein N-terminus DUF3951 PF13131.6 CBZ36114.1 - 3.3 8.0 10.6 5.2 7.3 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3951) PfkB PF00294.24 CBZ36115.1 - 8.2e-58 196.1 0.4 1.1e-57 195.7 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DAGK_cat PF00781.24 CBZ36115.1 - 0.029 14.0 0.0 0.1 12.2 0.0 1.8 1 1 0 1 1 1 0 Diacylglycerol kinase catalytic domain PfkB PF00294.24 CBZ36116.1 - 1.9e-14 53.7 0.0 2.9e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HECT PF00632.25 CBZ36118.1 - 6.5e-78 262.3 0.0 9.7e-78 261.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Cytochrom_B559 PF00283.19 CBZ36118.1 - 0.013 14.9 0.5 0.044 13.2 0.5 1.9 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits PSK_trans_fac PF07704.11 CBZ36118.1 - 0.36 11.6 3.6 1.9 9.3 3.6 2.3 1 0 0 1 1 1 0 Rv0623-like transcription factor Toxin_8 PF07365.12 CBZ36119.1 - 0.012 15.8 0.1 0.048 13.8 0.1 2.0 1 0 0 1 1 1 0 Alpha conotoxin precursor DUF2894 PF11445.8 CBZ36119.1 - 2.6 8.5 8.9 0.99 9.8 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2894) DUF4139 PF13598.6 CBZ36120.1 - 2.4e-22 79.7 0.0 4.7e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 CBZ36120.1 - 8.4e-06 26.1 6.1 0.00033 21.0 1.4 2.2 2 0 0 2 2 2 2 N-terminal domain of unknown function (DUF4140) PP-binding PF00550.25 CBZ36120.1 - 0.015 15.7 0.2 0.18 12.2 0.1 2.2 2 0 0 2 2 2 0 Phosphopantetheine attachment site Cast PF10174.9 CBZ36120.1 - 0.089 11.0 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Tropomyosin_1 PF12718.7 CBZ36120.1 - 0.09 12.9 2.4 2.6 8.2 0.1 2.2 2 0 0 2 2 2 0 Tropomyosin like ABC_tran_CTD PF16326.5 CBZ36120.1 - 0.33 11.2 0.2 0.33 11.2 0.2 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain Prefoldin_2 PF01920.20 CBZ36120.1 - 0.35 10.9 2.0 19 5.3 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit Sugarporin_N PF11471.8 CBZ36120.1 - 1.6 8.8 4.8 1.1 9.3 2.4 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension GCP_C_terminal PF04130.13 CBZ36121.1 - 1.8e-22 80.2 0.0 2.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CBZ36121.1 - 5.4e-05 23.0 0.0 0.00054 19.7 0.0 2.1 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal RWP-RK PF02042.15 CBZ36121.1 - 0.098 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 RWP-RK domain WD40 PF00400.32 CBZ36122.1 - 5.8e-12 45.9 8.6 7.3e-05 23.5 0.6 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CBZ36122.1 - 2.9e-10 40.3 0.0 6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CBZ36122.1 - 0.015 15.6 0.1 9.4 6.6 0.0 3.7 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain MAM33 PF02330.16 CBZ36124.1 - 6e-31 108.0 1.1 4.5e-28 98.6 1.1 2.1 1 1 0 1 1 1 1 Mitochondrial glycoprotein ABM PF03992.16 CBZ36124.1 - 0.034 14.3 0.1 0.35 11.0 0.0 2.4 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase APG5 PF04106.12 CBZ36125.1 - 0.0045 16.6 0.0 0.056 13.0 0.0 2.1 2 0 0 2 2 2 1 Autophagy protein Apg5 SLT PF01464.20 CBZ36125.1 - 0.092 12.4 0.2 0.36 10.5 0.0 2.0 3 0 0 3 3 3 0 Transglycosylase SLT domain E_Pc_C PF06752.12 CBZ36126.1 - 0.072 13.2 1.9 0.13 12.4 0.7 2.0 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Pkinase PF00069.25 CBZ36127.1 - 1e-34 120.1 0.0 6.9e-14 51.8 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36127.1 - 6.7e-22 78.0 0.0 3.4e-13 49.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ36127.1 - 0.062 12.6 0.0 0.84 8.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Med3 PF11593.8 CBZ36127.1 - 0.44 9.7 0.0 0.44 9.7 0.0 2.8 2 1 1 3 3 3 0 Mediator complex subunit 3 fungal Ufd2P_core PF10408.9 CBZ36128.1 - 3.4e-95 320.0 0.0 4.8e-95 319.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core Thioredoxin PF00085.20 CBZ36128.1 - 4.3e-21 74.8 0.0 9.4e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CBZ36128.1 - 7.7e-07 28.7 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CBZ36128.1 - 5.6e-06 26.8 0.2 2e-05 25.0 0.2 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain U-box PF04564.15 CBZ36128.1 - 0.00053 20.1 0.2 0.0044 17.2 0.1 2.7 2 1 0 2 2 2 1 U-box domain Thioredoxin_8 PF13905.6 CBZ36128.1 - 0.0016 18.7 0.0 0.21 11.9 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CBZ36128.1 - 0.002 17.9 0.0 0.0053 16.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CBZ36128.1 - 0.012 15.8 0.2 0.042 14.0 0.2 1.9 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 CBZ36128.1 - 0.038 13.9 0.1 0.16 11.9 0.1 1.9 1 1 0 1 1 1 0 AhpC/TSA family DUF2694 PF10904.8 CBZ36129.1 - 0.086 12.9 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) DnaJ PF00226.31 CBZ36130.1 - 0.0015 18.6 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain zf-CCHC_2 PF13696.6 CBZ36131.1 - 1.9 8.4 4.2 1.4 8.8 1.4 2.2 2 0 0 2 2 2 0 Zinc knuckle Mito_carr PF00153.27 CBZ36132.1 - 4.9e-47 157.8 2.7 2.9e-17 62.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RF-1 PF00472.20 CBZ36133.1 - 1.7e-15 57.0 0.0 2.7e-15 56.3 0.0 1.3 1 1 0 1 1 1 1 RF-1 domain TRF PF08558.10 CBZ36133.1 - 0.026 14.1 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) MRP-S28 PF10213.9 CBZ36133.1 - 0.05 14.0 0.0 0.067 13.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Sdh5 PF03937.16 CBZ36134.1 - 3.4e-19 68.6 0.4 6.6e-19 67.7 0.4 1.5 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase IQ PF00612.27 CBZ36135.1 - 1.1e-06 27.9 19.9 0.0057 16.3 0.2 5.3 5 0 0 5 5 5 4 IQ calmodulin-binding motif WW PF00397.26 CBZ36136.1 - 4.9e-10 39.3 2.2 9.1e-10 38.5 2.2 1.5 1 0 0 1 1 1 1 WW domain ATG16 PF08614.11 CBZ36136.1 - 0.0017 18.6 0.5 0.0017 18.6 0.5 2.6 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) DUF1465 PF07323.12 CBZ36136.1 - 0.026 14.4 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) YscO-like PF16789.5 CBZ36136.1 - 0.12 12.4 0.7 0.23 11.5 0.7 1.3 1 0 0 1 1 1 0 YscO-like protein DREV PF05219.12 CBZ36137.1 - 8.1e-63 212.0 0.0 9.6e-63 211.7 0.0 1.0 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_12 PF08242.12 CBZ36137.1 - 4.8e-12 46.5 0.0 8.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ36137.1 - 5.6e-12 45.8 0.0 7.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ36137.1 - 1.4e-11 44.9 0.0 2.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ36137.1 - 5.9e-09 36.5 0.0 1.1e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ36137.1 - 4.4e-05 23.3 0.1 0.00035 20.4 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 CBZ36137.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 CBZ36137.1 - 0.098 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 CBZ36137.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.4 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase RRM_1 PF00076.22 CBZ36138.1 - 1.1e-22 79.6 0.0 2e-09 37.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CBZ36138.1 - 0.0014 18.6 0.0 0.12 12.4 0.0 2.8 3 0 0 3 3 3 1 RNA binding domain DUF4523 PF15023.6 CBZ36138.1 - 0.0092 15.8 0.0 0.033 14.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 CBZ36138.1 - 0.0093 16.0 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Arm PF00514.23 CBZ36139.1 - 9e-69 225.6 19.5 4.2e-10 39.3 0.0 8.8 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 CBZ36139.1 - 6.1e-15 54.5 0.0 2e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 CBZ36139.1 - 1e-14 54.7 2.2 0.001 19.4 0.1 5.8 2 1 4 7 7 7 5 HEAT repeats HEAT_EZ PF13513.6 CBZ36139.1 - 2.6e-14 53.4 11.6 0.00015 22.2 0.2 6.9 5 2 3 8 8 8 3 HEAT-like repeat HEAT PF02985.22 CBZ36139.1 - 4e-12 45.3 11.5 0.084 13.2 0.0 8.0 9 0 0 9 9 9 4 HEAT repeat Arm_2 PF04826.13 CBZ36139.1 - 0.0076 15.7 0.0 0.31 10.4 0.0 3.2 3 1 1 4 4 4 2 Armadillo-like DCB PF16213.5 CBZ36139.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 MA3 PF02847.17 CBZ36142.1 - 1.8e-08 34.3 0.0 4.3e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 MA3 domain MCM_bind PF09739.9 CBZ36142.1 - 3 6.2 6.8 5 5.5 6.8 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DHHC PF01529.20 CBZ36144.1 - 1.6e-34 118.9 10.5 1.6e-34 118.9 10.5 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase TMEM107 PF14995.6 CBZ36145.1 - 7.2e-32 110.4 7.9 8.8e-32 110.1 7.9 1.1 1 0 0 1 1 1 1 Transmembrane protein Cupin_8 PF13621.6 CBZ36146.1 - 2.2e-20 73.5 0.0 1.6e-19 70.7 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CBZ36146.1 - 1.3e-09 38.4 0.1 2.6e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 JmjC domain, hydroxylase Cupin_2 PF07883.11 CBZ36146.1 - 0.00095 18.8 0.2 0.025 14.3 0.1 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_4 PF08007.12 CBZ36146.1 - 0.0022 17.5 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein F-box-like PF12937.7 CBZ36146.1 - 1.3 9.0 9.2 0.087 12.7 2.4 2.8 3 0 0 3 3 3 0 F-box-like LSM PF01423.22 CBZ36148.1 - 4e-14 52.0 0.1 4.6e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain AAA_28 PF13521.6 CBZ36149.1 - 1.1e-18 68.0 0.0 2.3e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CBZ36149.1 - 0.0062 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CBZ36149.1 - 0.018 14.7 0.2 0.057 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 CBZ36149.1 - 0.033 13.4 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Zeta_toxin PF06414.12 CBZ36149.1 - 0.053 12.8 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 CBZ36149.1 - 0.08 12.0 0.0 0.41 9.7 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 CBZ36149.1 - 0.083 12.7 0.2 0.58 9.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-C3HC4_3 PF13920.6 CBZ36150.1 - 7.9e-09 35.2 12.9 7.9e-09 35.2 12.9 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ36150.1 - 0.00013 21.7 13.7 0.00013 21.7 13.7 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ36150.1 - 0.014 15.2 12.9 0.014 15.2 12.9 3.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CBZ36150.1 - 0.018 15.4 14.6 0.018 15.4 14.6 3.6 2 1 1 3 3 3 0 Ring finger domain Rtf2 PF04641.12 CBZ36150.1 - 1.8 7.9 8.7 7.7 5.8 1.6 2.6 2 0 0 2 2 2 0 Rtf2 RING-finger Phos_pyr_kin PF08543.12 CBZ36152.1 - 1e-16 61.1 0.0 1.3e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CBZ36152.1 - 9e-10 38.3 1.7 7.2e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Acetyltransf_7 PF13508.7 CBZ36153.1 - 3.4e-05 24.2 0.0 0.0025 18.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ36153.1 - 0.0001 22.5 0.0 0.00038 20.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CBZ36153.1 - 0.003 17.5 0.1 0.098 12.6 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 CBZ36153.1 - 0.0061 16.6 0.0 0.052 13.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBZ36153.1 - 0.044 13.7 0.0 0.3 11.0 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CENP-F_leu_zip PF10473.9 CBZ36155.1 - 0.0002 21.4 1.4 0.0002 21.4 1.4 3.8 4 1 0 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.22 CBZ36155.1 - 0.015 15.6 0.5 0.015 15.6 0.5 4.6 4 1 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain Takusan PF04822.13 CBZ36155.1 - 0.13 12.2 3.2 0.16 11.9 0.3 2.7 2 0 0 2 2 2 0 Takusan DUF5320 PF17253.2 CBZ36155.1 - 1.3 10.1 6.0 91 4.2 0.0 4.3 3 1 1 4 4 4 0 Family of unknown function (DUF5320) NPV_P10 PF05531.12 CBZ36155.1 - 3.3 8.2 14.4 21 5.7 0.6 4.7 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 CBZ36155.1 - 5.5 5.5 13.3 0.37 9.4 8.1 1.6 2 0 0 2 2 2 0 AAA domain GIT_CC PF16559.5 CBZ36155.1 - 8.2 6.4 15.2 0.24 11.3 2.8 3.5 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Clathrin PF00637.20 CBZ36156.1 - 4.2e-09 36.4 0.1 2.9e-07 30.5 0.3 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 CBZ36156.1 - 0.00014 21.6 1.3 0.00049 19.9 1.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 CBZ36156.1 - 0.0035 17.4 1.8 0.0087 16.1 1.8 1.7 1 0 0 1 1 1 1 Zinc-finger zf-RING_2 PF13639.6 CBZ36156.1 - 0.0095 16.3 1.1 0.032 14.6 1.1 2.0 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CBZ36156.1 - 0.014 15.7 0.3 0.044 14.1 0.3 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CBZ36156.1 - 0.024 14.5 0.5 0.07 13.0 0.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) LysM PF01476.20 CBZ36156.1 - 0.053 13.6 0.0 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 LysM domain zf-RING_5 PF14634.6 CBZ36156.1 - 0.1 12.5 3.3 0.08 12.9 0.6 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 CBZ36156.1 - 0.26 11.1 2.5 0.95 9.3 2.5 2.1 1 0 0 1 1 1 0 RING-like zinc finger SAP130_C PF16014.5 CBZ36156.1 - 0.54 9.3 5.2 1.3 8.1 5.2 1.5 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Zn_ribbon_17 PF17120.5 CBZ36156.1 - 1.7 8.4 9.7 0.068 12.8 0.5 3.2 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Brix PF04427.18 CBZ36157.1 - 7e-30 104.6 0.3 9.3e-30 104.2 0.3 1.2 1 0 0 1 1 1 1 Brix domain Sarcoglycan_2 PF05510.13 CBZ36157.1 - 0.094 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon SNF2_N PF00176.23 CBZ36158.1 - 3.7e-43 147.6 0.0 6.1e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ36158.1 - 1.1e-09 38.6 0.0 2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ36158.1 - 0.00013 22.1 0.0 0.0004 20.4 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ36158.1 - 0.01 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Anillin_N PF16018.5 CBZ36159.1 - 0.62 10.7 3.1 1.5 9.5 1.8 2.4 2 0 0 2 2 2 0 Anillin N-terminus ABC_tran PF00005.27 CBZ36160.1 - 2.8e-19 70.0 0.6 1.1e-12 48.7 0.6 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CBZ36160.1 - 4.3e-09 36.6 0.8 0.00052 19.9 0.3 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ36160.1 - 9.5e-07 28.5 0.0 0.0072 15.8 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBZ36160.1 - 0.00044 20.7 0.1 0.014 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ36160.1 - 0.0011 18.9 0.1 0.0038 17.1 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase IstB_IS21 PF01695.17 CBZ36160.1 - 0.0024 17.6 0.6 1.7 8.3 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_29 PF13555.6 CBZ36160.1 - 0.0036 17.0 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 CBZ36160.1 - 0.0046 17.2 0.8 0.091 13.0 0.8 2.6 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBZ36160.1 - 0.035 13.8 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CBZ36160.1 - 0.047 14.2 0.1 0.076 13.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CBZ36160.1 - 0.097 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Dynamin family T2SSE PF00437.20 CBZ36160.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_15 PF13175.6 CBZ36160.1 - 0.17 11.6 0.1 0.23 11.1 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CBZ36160.1 - 0.49 10.7 1.6 2.3 8.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain RabGAP-TBC PF00566.18 CBZ36162.1 - 7.1e-36 123.9 0.2 1.2e-35 123.1 0.2 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RIO1 PF01163.22 CBZ36163.1 - 3.2e-45 154.1 0.0 5.8e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CBZ36163.1 - 4.5e-33 113.3 0.2 1.2e-31 108.7 0.3 2.4 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 CBZ36163.1 - 6.4e-10 39.3 0.1 1.2e-05 25.4 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CBZ36163.1 - 0.011 15.1 5.5 0.022 14.1 0.0 3.1 3 1 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family PSP1 PF04468.12 CBZ36164.1 - 8.3e-12 45.2 0.1 1.4e-11 44.5 0.1 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Peptidase_M20 PF01546.28 CBZ36165.1 - 6.4e-29 101.1 0.1 8.6e-29 100.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ36165.1 - 9.3e-08 32.0 0.1 2.3e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CBZ36165.1 - 0.012 15.3 0.3 0.019 14.7 0.3 1.3 1 0 0 1 1 1 0 Peptidase family M28 PLAC8 PF04749.17 CBZ36166.1 - 2.1e-15 57.5 13.2 2.9e-15 57.1 13.2 1.2 1 0 0 1 1 1 1 PLAC8 family WD40 PF00400.32 CBZ36167.1 - 3.8e-19 68.7 0.6 0.00092 20.0 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ36167.1 - 0.0028 17.9 0.0 1.5 9.2 0.0 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CBZ36167.1 - 0.085 11.5 0.1 4.2 5.9 0.1 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PLAC8 PF04749.17 CBZ36168.1 - 1.1e-11 45.5 23.6 1.4e-11 45.2 23.6 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.17 CBZ36169.1 - 1.3e-13 51.7 21.2 1.7e-13 51.4 21.2 1.1 1 0 0 1 1 1 1 PLAC8 family Kinesin PF00225.23 CBZ36172.1 - 1.1e-81 274.4 0.1 1.1e-81 274.4 0.1 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ36172.1 - 3.9e-17 62.6 0.0 9.3e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Serine_protease PF18405.1 CBZ36172.1 - 0.12 11.5 0.2 0.27 10.3 0.2 1.5 1 0 0 1 1 1 0 Gammaproteobacterial serine protease AAA_16 PF13191.6 CBZ36172.1 - 1.6 9.1 0.0 1.6 9.1 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 CBZ36172.1 - 5.8 5.4 16.9 3.2 6.3 14.5 1.6 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.9 CBZ36172.1 - 6.7 5.7 10.6 12 4.8 10.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 S1-P1_nuclease PF02265.16 CBZ36173.1 - 1.2e-32 113.7 0.1 1.3e-32 113.6 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PseudoU_synth_2 PF00849.22 CBZ36174.1 - 3.7e-31 108.4 0.0 3.6e-30 105.2 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUF2109 PF09882.9 CBZ36174.1 - 0.042 13.9 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) Rad17 PF03215.15 CBZ36175.1 - 3.6e-05 23.8 0.0 5.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CBZ36175.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Flavoprotein PF02441.19 CBZ36176.1 - 8.4e-48 162.1 0.3 1.6e-44 151.5 0.2 2.1 2 0 0 2 2 2 2 Flavoprotein GHMP_kinases_N PF00288.26 CBZ36176.1 - 0.059 13.6 0.4 0.16 12.2 0.4 1.8 1 0 0 1 1 1 0 GHMP kinases N terminal domain PseudoU_synth_1 PF01416.20 CBZ36178.1 - 1.6e-27 96.0 0.0 1.1e-25 90.1 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pkinase PF00069.25 CBZ36179.1 - 1.9e-31 109.4 0.0 9.4e-12 44.8 0.1 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36179.1 - 1.3e-14 54.1 0.0 6.3e-06 25.7 0.1 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ36179.1 - 0.003 16.4 0.0 0.0079 15.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Rubredoxin_2 PF18073.1 CBZ36179.1 - 0.23 11.2 1.4 0.74 9.6 1.4 1.8 1 0 0 1 1 1 0 Rubredoxin metal binding domain DUF1796 PF08795.10 CBZ36180.1 - 1.3e-66 223.8 0.0 1.9e-66 223.2 0.0 1.3 1 0 0 1 1 1 1 Putative papain-like cysteine peptidase (DUF1796) Kelch_4 PF13418.6 CBZ36181.1 - 1.1e-07 31.7 2.2 0.081 13.0 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain PH PF00169.29 CBZ36181.1 - 1.6e-06 28.6 2.9 0.0018 18.8 0.3 2.6 2 1 0 2 2 2 2 PH domain Kelch_3 PF13415.6 CBZ36181.1 - 0.0035 17.6 2.1 31 5.0 0.1 5.7 6 0 0 6 6 6 0 Galactose oxidase, central domain DUF4846 PF16138.5 CBZ36181.1 - 0.088 12.3 0.0 0.21 11.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (4846) Albumin_I PF08027.11 CBZ36181.1 - 0.37 10.5 3.2 6.3 6.5 0.0 3.1 3 0 0 3 3 3 0 Albumin I chain b Med3 PF11593.8 CBZ36181.1 - 5.1 6.2 8.2 1.6 7.8 2.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Kelch_1 PF01344.25 CBZ36181.1 - 8.7 6.0 10.8 2.3 7.9 0.1 4.2 6 0 0 6 6 6 0 Kelch motif DUF2142 PF09913.9 CBZ36182.1 - 0.29 9.9 1.5 1.1 8.1 0.9 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) Actin PF00022.19 CBZ36183.1 - 0.003 16.2 0.0 0.0064 15.1 0.0 1.4 1 0 0 1 1 1 1 Actin Apt1 PF10351.9 CBZ36183.1 - 1.4 7.7 4.2 1.9 7.2 4.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain NAD_binding_6 PF08030.12 CBZ36184.1 - 2e-17 63.7 0.1 1.9e-08 34.6 0.0 2.9 2 1 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 CBZ36184.1 - 5.1e-15 55.7 11.0 2e-14 53.8 11.0 2.1 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CBZ36184.1 - 1.2e-08 35.0 0.0 2.3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 CBZ36184.1 - 0.022 15.1 0.0 0.067 13.6 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBZ36184.1 - 0.16 12.6 0.0 5.3 7.7 0.0 2.7 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Smim3 PF17307.2 CBZ36184.1 - 0.22 11.1 0.6 0.5 9.9 0.6 1.6 1 0 0 1 1 1 0 Small integral membrane protein 3 DUF1077 PF06417.12 CBZ36187.1 - 1.4e-35 121.9 1.0 1.6e-35 121.6 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) ThrE PF06738.12 CBZ36187.1 - 0.0028 17.0 0.5 0.0047 16.3 0.5 1.5 1 1 0 1 1 1 1 Putative threonine/serine exporter PqiA PF04403.13 CBZ36187.1 - 0.0073 16.1 1.2 0.0094 15.8 1.2 1.1 1 0 0 1 1 1 1 Paraquat-inducible protein A DUF4064 PF13273.6 CBZ36187.1 - 0.015 15.6 0.3 0.022 15.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF1189 PF06691.11 CBZ36187.1 - 0.015 14.9 0.0 4.5 6.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1189) HSP33 PF01430.19 CBZ36188.1 - 4.5e-14 52.5 0.0 2.4e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Hsp33 protein CRAL_TRIO PF00650.20 CBZ36189.1 - 2.5e-21 76.0 0.0 3.2e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBZ36189.1 - 0.0027 17.8 0.0 0.0038 17.4 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CBZ36189.1 - 0.016 15.3 0.0 0.037 14.2 0.0 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain ATXN-1_C PF12547.8 CBZ36190.1 - 0.22 11.9 0.1 0.22 11.9 0.1 2.7 2 1 1 3 3 3 0 Capicua transcriptional repressor modulator AAA_2 PF07724.14 CBZ36191.1 - 3.3e-07 30.6 0.0 5.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CBZ36191.1 - 6.6e-06 26.4 0.0 6.4e-05 23.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ36191.1 - 3.6e-05 23.8 0.0 9.6e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2721 PF11026.8 CBZ36191.1 - 9.8e-05 22.2 1.1 0.00027 20.8 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) AAA PF00004.29 CBZ36191.1 - 0.0036 17.7 0.0 0.0076 16.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ36191.1 - 0.03 14.7 0.2 0.92 9.9 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 CBZ36191.1 - 0.032 14.4 0.8 0.37 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain KASH_CCD PF14662.6 CBZ36191.1 - 1.4 8.8 8.4 0.69 9.7 0.9 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Ras PF00071.22 CBZ36192.1 - 5.4e-38 130.2 0.0 6.5e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ36192.1 - 2.7e-25 88.9 0.0 4.4e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ36192.1 - 1.8e-10 40.6 0.0 2.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBZ36192.1 - 0.0017 18.4 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBZ36192.1 - 0.0032 16.8 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBZ36192.1 - 0.0042 17.0 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CBZ36192.1 - 0.0042 16.6 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Ribonuc_red_lgN PF00317.21 CBZ36192.1 - 0.041 13.9 0.1 0.087 12.8 0.1 1.5 1 1 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain AAA_16 PF13191.6 CBZ36192.1 - 0.055 13.9 0.0 0.096 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.20 CBZ36192.1 - 0.067 12.3 0.0 6.8 5.7 0.0 2.4 1 1 1 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 CBZ36192.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Fez1 PF06818.15 CBZ36194.1 - 0.0019 18.7 3.1 0.0019 18.7 3.1 2.2 2 0 0 2 2 2 1 Fez1 Spc29 PF17082.5 CBZ36194.1 - 0.011 15.6 11.2 2.6 7.8 0.6 3.3 2 1 1 3 3 3 0 Spindle Pole Component 29 ATG16 PF08614.11 CBZ36194.1 - 0.013 15.8 27.7 0.057 13.6 9.2 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 CBZ36194.1 - 0.02 15.4 21.9 0.2 12.2 3.7 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Rootletin PF15035.6 CBZ36194.1 - 0.046 13.7 19.6 0.68 9.9 9.6 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 CBZ36194.1 - 0.39 10.8 27.4 0.23 11.5 7.3 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 CBZ36194.1 - 0.44 10.4 23.8 0.065 13.0 2.3 3.3 2 1 1 3 3 3 0 Septum formation initiator GAS PF13851.6 CBZ36194.1 - 0.67 9.3 22.0 0.27 10.6 6.3 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 CBZ36194.1 - 1.5 8.8 25.9 9.9 6.2 12.0 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAUS-augmin3 PF14932.6 CBZ36194.1 - 7.2 6.1 20.9 0.12 11.9 4.2 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3450 PF11932.8 CBZ36194.1 - 7.3 5.8 23.2 8.9 5.5 7.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) RVT_3 PF13456.6 CBZ36196.1 - 0.063 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like CLASP_N PF12348.8 CBZ36197.1 - 1.3e-10 41.2 3.7 1.1e-06 28.4 0.1 4.1 5 0 0 5 5 5 2 CLASP N terminal NUC173 PF08161.12 CBZ36197.1 - 0.011 15.4 1.9 0.61 9.7 0.1 4.1 5 0 0 5 5 5 0 NUC173 domain Cnd1 PF12717.7 CBZ36197.1 - 0.071 13.1 3.6 28 4.7 0.0 4.0 2 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ36197.1 - 0.11 12.9 17.3 0.31 11.5 0.2 6.7 7 1 0 7 7 7 0 HEAT repeats PPP4R2 PF09184.11 CBZ36197.1 - 0.75 9.3 2.7 3.7 7.0 0.9 2.3 2 0 0 2 2 2 0 PPP4R2 FSA_C PF10479.9 CBZ36197.1 - 6.4 4.8 8.9 14 3.7 8.9 1.5 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus HEAT PF02985.22 CBZ36197.1 - 9.2 6.8 15.2 13 6.3 0.1 7.1 8 0 0 8 8 8 0 HEAT repeat IFT46_B_C PF12317.8 CBZ36198.1 - 2.8e-79 265.8 0.1 3.5e-79 265.4 0.1 1.1 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Voldacs PF03517.13 CBZ36198.1 - 0.041 14.0 1.4 0.075 13.1 1.4 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling NOA36 PF06524.12 CBZ36198.1 - 1.9 7.7 5.9 2.8 7.2 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein Pkinase PF00069.25 CBZ36199.1 - 6e-30 104.5 0.0 1.4e-27 96.8 0.0 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36199.1 - 4.6e-09 35.9 0.0 8.2e-06 25.3 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ36199.1 - 0.0032 17.4 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DnaJ PF00226.31 CBZ36200.1 - 8.1e-20 70.7 0.3 2.5e-19 69.2 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain TGT PF01702.18 CBZ36201.1 - 1.5e-125 419.0 0.0 1.1e-92 310.9 0.0 2.1 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase ASH PF15780.5 CBZ36202.1 - 2.3e-53 178.4 47.3 3.5e-07 30.3 0.2 31.2 35 0 0 35 35 34 10 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CBZ36202.1 - 3.5e-23 81.7 26.8 0.00042 20.4 0.1 14.7 17 0 0 17 17 16 5 Flagellar-associated PapD-like Motile_Sperm PF00635.26 CBZ36202.1 - 4.3e-16 58.7 3.3 0.25 11.2 0.0 12.5 13 0 0 13 13 12 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 CBZ36202.1 - 1.3e-13 50.8 0.3 8.5 6.5 0.0 13.6 17 0 0 17 17 17 1 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 CBZ36202.1 - 1.8e-07 30.5 0.0 18 4.1 0.0 7.8 7 1 0 8 8 8 0 MYCBP-associated protein family AAA_33 PF13671.6 CBZ36202.1 - 1.4e-05 25.3 1.0 3.3e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CBZ36202.1 - 0.00019 20.8 0.2 0.0011 18.3 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin DUF5001 PF16392.5 CBZ36202.1 - 0.00047 20.0 3.5 12 5.9 0.1 7.2 9 0 0 9 9 8 0 Ig-like domain TMEM131_like PF12371.8 CBZ36202.1 - 0.0011 19.1 14.1 16 5.8 0.1 9.5 12 0 0 12 12 10 0 Transmembrane protein 131-like NACHT PF05729.12 CBZ36202.1 - 0.0037 17.2 0.0 0.022 14.7 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CBZ36202.1 - 0.0042 17.5 2.8 0.0089 16.4 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain KTI12 PF08433.10 CBZ36202.1 - 0.0069 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 CBZ36202.1 - 0.028 14.7 0.0 0.076 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Trigger_C PF05698.14 CBZ36202.1 - 0.035 14.1 1.3 0.066 13.2 1.3 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus PapD_N PF00345.20 CBZ36202.1 - 0.038 13.9 0.2 4.8 7.1 0.0 4.3 4 0 0 4 4 3 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain AAA_28 PF13521.6 CBZ36202.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBZ36202.1 - 0.16 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CBZ36202.1 - 0.17 12.4 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3449 PF11931.8 CBZ36203.1 - 2e-38 132.1 2.7 2.6e-38 131.7 0.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 CBZ36203.1 - 2.4e-09 37.6 0.0 9.6e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-RING_7 PF02591.15 CBZ36203.1 - 0.084 13.1 0.0 22 5.4 0.0 3.0 2 0 0 2 2 2 0 C4-type zinc ribbon domain FYVE PF01363.21 CBZ36205.1 - 1.2e-11 44.6 8.7 1.6e-11 44.2 5.3 2.8 2 0 0 2 2 2 1 FYVE zinc finger PI3_PI4_kinase PF00454.27 CBZ36205.1 - 1e-09 38.6 0.3 9.3e-08 32.2 0.1 2.5 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase IBR PF01485.21 CBZ36205.1 - 0.029 14.6 2.2 0.13 12.5 2.2 2.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain OrfB_Zn_ribbon PF07282.11 CBZ36205.1 - 0.44 10.5 2.8 1.5 8.8 2.8 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain MCR PF18509.1 CBZ36208.2 - 0.056 13.0 1.1 0.35 10.5 0.1 2.1 2 0 0 2 2 2 0 Magnetochrome domain AAA_18 PF13238.6 CBZ36209.1 - 1.3e-27 96.9 0.0 2e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CBZ36209.1 - 1.3e-07 32.2 1.6 2.2e-07 31.4 0.2 2.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CBZ36209.1 - 2.5e-07 31.0 0.2 0.00011 22.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CBZ36209.1 - 1.5e-05 25.4 0.5 3.1e-05 24.4 0.5 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBZ36209.1 - 0.00021 21.1 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CBZ36209.1 - 0.00021 21.6 4.0 0.00038 20.7 0.1 2.4 1 1 2 3 3 3 1 AAA domain AAA_22 PF13401.6 CBZ36209.1 - 0.00028 21.2 0.0 0.00083 19.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain dNK PF01712.19 CBZ36209.1 - 0.00097 19.0 0.8 0.43 10.4 0.1 2.3 1 1 0 2 2 2 2 Deoxynucleoside kinase ADK PF00406.22 CBZ36209.1 - 0.0015 18.7 0.1 0.25 11.4 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase NTPase_1 PF03266.15 CBZ36209.1 - 0.0018 18.2 0.6 0.01 15.8 0.0 2.3 2 1 0 2 2 2 1 NTPase AAA_16 PF13191.6 CBZ36209.1 - 0.003 17.9 0.1 0.0041 17.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Parvo_NS1 PF01057.17 CBZ36209.1 - 0.0066 15.6 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 DUF2075 PF09848.9 CBZ36209.1 - 0.0067 15.7 0.1 0.0089 15.3 0.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 CBZ36209.1 - 0.0069 16.4 0.0 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CBZ36209.1 - 0.011 15.5 0.8 0.033 13.9 0.2 2.0 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 CBZ36209.1 - 0.012 16.2 1.7 0.079 13.5 1.7 2.0 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 CBZ36209.1 - 0.012 14.9 0.2 0.024 13.9 0.0 1.7 2 1 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 CBZ36209.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 CBZ36209.1 - 0.015 14.7 0.1 0.053 12.9 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CBZ36209.1 - 0.016 15.6 1.2 0.024 15.0 0.1 1.8 2 1 0 2 2 2 0 AAA domain SKI PF01202.22 CBZ36209.1 - 0.017 15.2 4.3 0.22 11.6 4.3 2.2 1 1 0 1 1 1 0 Shikimate kinase ATPase_2 PF01637.18 CBZ36209.1 - 0.018 14.9 0.2 0.039 13.9 0.2 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ATPase PF06745.13 CBZ36209.1 - 0.019 14.4 1.8 0.02 14.2 0.1 1.8 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 CBZ36209.1 - 0.019 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain CoaE PF01121.20 CBZ36209.1 - 0.02 14.6 0.4 0.69 9.6 0.1 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase TIP49 PF06068.13 CBZ36209.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Torsin PF06309.11 CBZ36209.1 - 0.031 14.4 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Torsin KTI12 PF08433.10 CBZ36209.1 - 0.037 13.5 0.1 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CPT PF07931.12 CBZ36209.1 - 0.041 13.7 3.4 0.63 9.9 0.0 2.9 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein KAP_NTPase PF07693.14 CBZ36209.1 - 0.046 12.9 0.0 0.052 12.8 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.17 CBZ36209.1 - 0.047 13.4 0.3 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 CBZ36209.1 - 0.053 13.0 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sars6 PF12133.8 CBZ36209.1 - 0.087 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus AAA_3 PF07726.11 CBZ36209.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CBZ36209.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.17 CBZ36209.1 - 0.21 11.3 3.1 7.9 6.1 0.1 2.3 1 1 1 2 2 2 0 Thymidylate kinase FYVE PF01363.21 CBZ36211.1 - 0.057 13.6 3.8 0.44 10.7 0.1 2.6 2 0 0 2 2 2 0 FYVE zinc finger CoA_trans PF01144.23 CBZ36212.1 - 3.6e-47 160.6 0.0 4e-47 160.4 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase CoA_trans PF01144.23 CBZ36213.1 - 3.9e-33 114.7 0.2 4.4e-33 114.5 0.2 1.0 1 0 0 1 1 1 1 Coenzyme A transferase PseudoU_synth_2 PF00849.22 CBZ36215.1 - 2.3e-21 76.5 0.3 1.4e-12 48.0 0.1 2.6 2 0 0 2 2 2 2 RNA pseudouridylate synthase S4 PF01479.25 CBZ36215.1 - 0.008 15.9 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 S4 domain TPR_MLP1_2 PF07926.12 CBZ36216.1 - 0.15 12.1 17.8 0.29 11.2 1.8 3.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1154 PF06631.11 CBZ36216.1 - 0.19 11.7 3.5 0.31 11.1 2.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1154) BILBO1_N PF18281.1 CBZ36217.1 - 4.1e-21 75.2 0.0 7e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 BILBO1 N-terminal domain zf-C2H2_2 PF12756.7 CBZ36218.1 - 1.1e-19 70.7 7.7 8.5e-14 51.7 1.5 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CBZ36218.1 - 1.8e-06 28.3 7.4 2 9.5 0.0 4.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 CBZ36218.1 - 5.5e-05 23.4 13.1 0.0014 18.9 0.3 4.0 3 1 1 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding zf-ISL3 PF14690.6 CBZ36218.1 - 0.024 15.3 0.1 0.079 13.6 0.1 1.9 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 PC_rep PF01851.22 CBZ36220.1 - 0.0014 19.0 9.1 17 6.1 0.1 6.8 7 0 0 7 7 7 3 Proteasome/cyclosome repeat IFT20 PF14931.6 CBZ36221.1 - 8.1e-35 119.6 7.4 9e-35 119.4 7.4 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 VQ PF05678.14 CBZ36221.1 - 0.013 14.9 1.9 0.72 9.4 0.1 2.9 3 0 0 3 3 3 0 VQ motif Haem_bd PF14376.6 CBZ36221.1 - 0.03 14.3 0.2 0.039 13.9 0.2 1.2 1 0 0 1 1 1 0 Haem-binding domain DUF459 PF04311.13 CBZ36221.1 - 0.041 12.9 0.0 0.054 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF459) ISG65-75 PF11727.8 CBZ36221.1 - 0.3 10.3 2.9 0.37 10.0 2.9 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Mannosyl_trans PF05007.13 CBZ36224.1 - 1.6e-83 280.6 12.8 2.2e-83 280.1 12.8 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) GT87 PF09594.10 CBZ36224.1 - 9.3e-09 35.4 14.4 9.3e-09 35.4 14.4 2.7 1 1 1 2 2 2 1 Glycosyltransferase family 87 PIG-U PF06728.13 CBZ36224.1 - 3e-08 33.1 16.9 1.3e-07 31.0 16.7 1.9 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Peptidase_C2 PF00648.21 CBZ36225.1 - 1.2e-26 93.5 0.0 3.5e-12 45.9 0.0 4.1 4 0 0 4 4 4 3 Calpain family cysteine protease Calpain_III PF01067.22 CBZ36225.1 - 0.0034 17.7 0.0 0.51 10.6 0.0 2.8 3 0 0 3 3 3 1 Calpain large subunit, domain III LRR_4 PF12799.7 CBZ36225.1 - 0.046 14.2 9.1 0.39 11.2 3.2 2.8 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ36225.1 - 0.12 12.5 3.4 16 5.9 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ36225.1 - 0.26 12.0 6.9 27 5.8 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat zf-RING_UBOX PF13445.6 CBZ36227.1 - 3.3e-05 23.8 7.4 0.00011 22.1 7.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ36227.1 - 0.0015 18.3 5.3 0.0015 18.3 5.3 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ36227.1 - 0.006 16.7 10.3 0.006 16.7 10.3 2.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CBZ36227.1 - 0.008 16.0 4.8 0.008 16.0 4.8 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) NFACT-R_1 PF05670.13 CBZ36229.1 - 1.1e-43 148.3 0.0 1.7e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF3987 PF13148.6 CBZ36229.1 - 3 6.8 7.9 3.8 6.4 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Tho2 PF11262.8 CBZ36229.1 - 5.5 6.1 8.1 7.5 5.7 8.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 AAA_16 PF13191.6 CBZ36230.1 - 0.0036 17.7 0.3 0.014 15.8 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 CBZ36230.1 - 0.011 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 CBZ36230.1 - 0.019 15.5 0.0 0.068 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBZ36230.1 - 0.034 14.4 0.0 0.12 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBZ36230.1 - 0.039 13.7 0.2 0.11 12.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain CbiA PF01656.23 CBZ36230.1 - 0.055 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 CBZ36230.1 - 0.19 11.8 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_19 PF13245.6 CBZ36230.1 - 0.22 11.8 1.5 0.66 10.3 0.0 2.4 3 0 0 3 3 3 0 AAA domain Fe-ADH PF00465.19 CBZ36231.1 - 1.2e-116 389.5 1.3 1.4e-116 389.3 1.3 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CBZ36231.1 - 7.6e-20 71.7 0.1 1.7e-12 47.6 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase PFK PF00365.20 CBZ36231.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphofructokinase DUF1664 PF07889.12 CBZ36232.1 - 2.7e-05 24.2 0.7 7.6e-05 22.7 0.7 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DUF883 PF05957.13 CBZ36232.1 - 0.0092 16.6 1.7 0.038 14.6 1.7 2.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Exonuc_VII_L PF02601.15 CBZ36232.1 - 0.01 15.4 0.9 0.01 15.4 0.9 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit Apolipoprotein PF01442.18 CBZ36232.1 - 0.015 15.2 3.0 0.042 13.7 3.0 1.7 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain FTA4 PF13093.6 CBZ36232.1 - 0.035 14.0 0.3 0.082 12.8 0.2 1.7 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GCP_N_terminal PF17681.1 CBZ36232.1 - 0.041 13.5 0.6 0.069 12.8 0.6 1.3 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal Baculo_PEP_C PF04513.12 CBZ36232.1 - 0.043 13.9 1.0 0.085 12.9 1.0 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HisKA_3 PF07730.13 CBZ36232.1 - 0.052 14.1 2.1 0.31 11.6 2.1 2.4 1 0 0 1 1 1 0 Histidine kinase FlgN PF05130.12 CBZ36232.1 - 0.085 13.4 6.0 0.13 12.7 4.5 2.1 2 0 0 2 2 2 0 FlgN protein DUF4164 PF13747.6 CBZ36232.1 - 0.1 12.9 1.1 0.3 11.4 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Sigma70_ner PF04546.13 CBZ36232.1 - 0.12 12.3 1.1 0.21 11.4 1.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Salp15 PF12115.8 CBZ36232.1 - 0.13 12.8 0.3 0.27 11.7 0.3 1.6 1 0 0 1 1 1 0 Salivary protein of 15kDa inhibits CD4+ T cell activation OmpH PF03938.14 CBZ36232.1 - 0.2 12.0 4.0 0.53 10.6 4.0 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fzo_mitofusin PF04799.13 CBZ36232.1 - 0.27 10.8 2.9 0.64 9.6 2.9 1.5 1 0 0 1 1 1 0 fzo-like conserved region DUF148 PF02520.17 CBZ36232.1 - 1.4 9.1 6.4 2.5 8.2 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 PMEI PF04043.15 CBZ36232.1 - 5.2 7.4 9.3 21 5.4 0.1 2.9 3 1 0 3 3 2 0 Plant invertase/pectin methylesterase inhibitor Sex_peptide PF08138.11 CBZ36234.1 - 0.066 13.4 1.6 0.15 12.2 1.3 1.7 2 0 0 2 2 2 0 Sex peptide (SP) family E1-N PF14463.6 CBZ36234.1 - 0.23 11.3 0.4 0.33 10.8 0.4 1.2 1 0 0 1 1 1 0 E1 N-terminal domain Pkinase PF00069.25 CBZ36235.1 - 6.2e-52 176.6 0.0 3.5e-38 131.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36235.1 - 1.2e-34 119.8 0.0 2e-27 96.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Beta_helix PF13229.6 CBZ36235.1 - 1.2e-28 99.9 8.9 2.3e-14 53.6 5.2 2.5 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 CBZ36235.1 - 1.6e-24 86.5 0.3 2.4e-15 56.5 0.8 2.5 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Kinase-like PF14531.6 CBZ36235.1 - 0.0003 20.2 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF1565 PF07602.11 CBZ36235.1 - 0.0017 17.7 5.4 0.079 12.3 5.4 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) zf-B_box PF00643.24 CBZ36235.1 - 0.003 17.7 7.3 0.0088 16.2 7.3 1.7 1 0 0 1 1 1 1 B-box zinc finger APH PF01636.23 CBZ36235.1 - 0.014 15.3 0.0 0.19 11.7 0.0 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family CEBP_ZZ PF16366.5 CBZ36235.1 - 0.11 12.8 7.1 0.32 11.3 7.1 1.8 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Kdo PF06293.14 CBZ36235.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IBR PF01485.21 CBZ36235.1 - 0.29 11.4 7.6 1.8 8.9 7.6 2.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Patatin PF01734.22 CBZ36236.1 - 7.3e-23 81.8 0.1 6.5e-22 78.7 0.0 2.6 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.8 CBZ36236.1 - 3.1e-07 30.2 0.0 5.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) WD40 PF00400.32 CBZ36237.1 - 1.8e-08 34.9 11.8 0.33 11.9 0.0 8.0 8 1 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ36237.1 - 0.0014 18.9 0.0 1.9 8.8 0.0 4.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Herpes_TAF50 PF03326.13 CBZ36238.1 - 0.074 11.7 1.0 0.11 11.1 1.0 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) IBR PF01485.21 CBZ36239.1 - 4e-14 52.6 27.9 7.9e-09 35.6 14.1 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 CBZ36239.1 - 0.011 15.7 4.6 0.011 15.7 4.6 3.1 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ36239.1 - 0.022 14.7 12.9 0.022 14.7 12.9 4.2 3 1 1 4 4 4 0 zinc-RING finger domain MctB PF11382.8 CBZ36239.1 - 0.075 12.7 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Copper transport outer membrane protein, MctB Chor_lyase PF04345.13 CBZ36239.1 - 0.082 12.6 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Chorismate lyase UBA_4 PF14555.6 CBZ36239.1 - 0.089 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain zf-C3HC4 PF00097.25 CBZ36239.1 - 1.3 8.9 40.7 0.058 13.3 10.8 3.9 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CBZ36240.1 - 3.1e-25 87.8 0.0 1.1e-13 50.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBZ36240.1 - 0.016 15.2 0.0 7.3 6.7 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif RRM_Rrp7 PF17799.1 CBZ36240.1 - 0.064 13.1 0.0 0.33 10.7 0.0 2.0 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 CBZ36241.1 - 6.1e-24 83.6 1.7 3.1e-14 52.5 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CBZ36241.1 - 0.0094 15.8 0.5 0.4 10.5 0.0 2.3 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CBZ36241.1 - 0.045 13.9 0.0 0.65 10.1 0.0 2.5 2 1 0 2 2 2 0 RNA recognition motif zf-CCCH PF00642.24 CBZ36242.1 - 2.8e-08 33.5 0.4 3.9e-08 33.0 0.4 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ36242.1 - 7.9e-07 28.7 0.8 1.1e-06 28.3 0.8 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ36242.1 - 7.1e-05 22.7 0.6 0.00021 21.2 0.6 1.8 1 1 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ36242.1 - 0.00091 19.6 0.8 0.0014 19.0 0.8 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CBZ36242.1 - 0.1 12.8 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger containing family Torus PF16131.5 CBZ36242.1 - 0.18 12.5 0.0 0.26 12.0 0.0 1.3 1 0 0 1 1 1 0 Torus domain GYF_2 PF14237.6 CBZ36243.1 - 5e-18 64.6 0.4 5e-18 64.6 0.4 2.0 2 0 0 2 2 2 1 GYF domain 2 DnaJ PF00226.31 CBZ36243.1 - 6.2e-15 55.1 0.4 1.5e-14 53.9 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain CDC14 PF08045.11 CBZ36243.1 - 0.065 12.3 0.7 0.15 11.1 0.7 1.5 1 0 0 1 1 1 0 Cell division control protein 14, SIN component DUF155 PF02582.14 CBZ36244.1 - 6.5e-19 68.7 0.0 1.5e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Alkyl_sulf_dimr PF14863.6 CBZ36244.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation Mito_carr PF00153.27 CBZ36246.1 - 1.7e-09 37.5 9.8 0.11 12.5 0.0 5.1 5 1 0 5 5 5 4 Mitochondrial carrier protein CytB6-F_Fe-S PF08802.10 CBZ36246.1 - 2.3 8.3 5.5 0.22 11.6 0.5 1.8 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit zf-C2H2_2 PF12756.7 CBZ36247.1 - 3.4e-24 85.1 7.5 2.9e-18 66.1 1.3 3.1 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CBZ36247.1 - 1.1e-10 41.4 5.8 3.3e-07 30.4 0.7 3.9 3 1 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CBZ36247.1 - 1.2e-06 28.4 8.6 0.0046 16.9 1.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CBZ36247.1 - 4.6e-06 27.0 10.5 0.0034 18.1 1.3 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 CBZ36247.1 - 0.0002 21.7 13.1 0.007 16.7 2.5 3.8 3 1 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_12 PF18658.1 CBZ36247.1 - 0.00055 19.5 9.8 0.018 14.6 0.1 3.7 2 1 1 3 3 3 1 Zinc-finger C2H2-type zf-C2H2 PF00096.26 CBZ36247.1 - 0.0038 17.6 15.9 0.05 14.1 2.7 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf_Hakai PF18408.1 CBZ36247.1 - 0.042 13.6 0.7 0.14 11.9 0.7 2.0 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain zf-LYAR PF08790.11 CBZ36247.1 - 1.2 9.1 5.3 0.25 11.3 1.2 2.1 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger PhoLip_ATPase_C PF16212.5 CBZ36248.1 - 3.5e-39 135.1 14.4 8.5e-39 133.8 14.4 1.7 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBZ36248.1 - 3.8e-19 68.1 2.9 8.6e-19 67.0 2.9 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CBZ36248.1 - 4.2e-11 43.5 0.2 3.2e-05 24.3 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ36248.1 - 2.1e-07 30.9 0.0 6.2e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBZ36248.1 - 0.00014 21.5 0.0 0.00072 19.1 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBZ36248.1 - 0.011 15.5 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase KRTAP7 PF15034.6 CBZ36248.1 - 0.17 12.9 1.1 0.4 11.7 0.0 2.1 2 0 0 2 2 2 0 KRTAP type 7 family TTL PF03133.15 CBZ36250.1 - 3.5e-49 167.5 0.0 5.2e-30 104.6 0.0 3.1 3 0 0 3 3 3 3 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ36250.1 - 2.4e-07 30.2 0.0 0.008 15.4 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 CBZ36250.1 - 1.3e-05 24.6 0.0 0.038 13.2 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 CBZ36250.1 - 0.096 12.2 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DEAD PF00270.29 CBZ36251.1 - 1.6e-13 50.8 0.0 5.5e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ36251.1 - 1.2e-12 48.1 0.0 3e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Drf_FH3 PF06367.16 CBZ36252.1 - 0.19 11.4 4.4 0.31 10.6 4.4 1.3 1 0 0 1 1 1 0 Diaphanous FH3 Domain Spc7 PF08317.11 CBZ36252.1 - 1.2 7.9 12.0 2.1 7.1 12.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 CBZ36252.1 - 2.7 5.4 23.6 3.8 4.9 23.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PUA_3 PF17785.1 CBZ36253.1 - 0.016 15.0 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 PUA-like domain SET PF00856.28 CBZ36254.1 - 1.3e-09 38.6 0.0 2.3e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 SET domain HTH_29 PF13551.6 CBZ36254.1 - 0.057 13.4 0.9 1.4 9.0 0.6 2.6 2 0 0 2 2 2 0 Winged helix-turn helix zf-C2H2_4 PF13894.6 CBZ36256.1 - 0.098 13.6 0.7 0.25 12.3 0.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger ZapB PF06005.12 CBZ36256.1 - 0.19 12.2 8.0 0.37 11.2 0.3 3.2 3 0 0 3 3 3 0 Cell division protein ZapB zf-C2H2 PF00096.26 CBZ36256.1 - 0.2 12.2 0.6 0.44 11.1 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Pyridoxal_deC PF00282.19 CBZ36257.1 - 1.1e-16 60.6 0.0 2.4e-16 59.4 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CBZ36257.1 - 7.6e-11 41.6 0.0 2.3e-10 40.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CBZ36257.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family CooT PF10133.9 CBZ36257.1 - 0.16 12.3 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 CO dehydrogenase accessory protein CooT zf-C3HC4 PF00097.25 CBZ36258.1 - 1.6e-08 34.3 6.2 1.6e-08 34.3 6.2 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CBZ36258.1 - 3.7e-08 33.1 7.3 3.7e-08 33.1 7.3 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CBZ36258.1 - 6.3e-08 32.6 7.5 6.3e-08 32.6 7.5 3.8 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CBZ36258.1 - 8.2e-08 32.1 6.6 8.2e-08 32.1 6.6 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-B_box PF00643.24 CBZ36258.1 - 6.2e-07 29.5 7.3 6.2e-07 29.5 7.3 4.3 4 1 0 4 4 4 2 B-box zinc finger Flg_hook PF02120.16 CBZ36258.1 - 0.043 13.7 0.6 0.16 11.9 0.6 1.9 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Apolipoprotein PF01442.18 CBZ36258.1 - 0.88 9.4 10.1 2.2 8.1 10.1 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Arf PF00025.21 CBZ36259.1 - 1.9e-49 167.5 0.0 2.1e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBZ36259.1 - 1.1e-17 64.1 0.0 1.4e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBZ36259.1 - 3.4e-11 43.0 0.0 4.1e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBZ36259.1 - 6.4e-11 42.0 0.0 1.4e-06 27.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CBZ36259.1 - 1.8e-10 40.9 0.0 2.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CBZ36259.1 - 7.4e-10 39.1 0.0 1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBZ36259.1 - 4.1e-06 26.3 0.0 8.6e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 CBZ36259.1 - 0.00022 20.8 0.0 0.00036 20.1 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CBZ36259.1 - 0.0076 15.8 0.1 0.11 12.0 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CBZ36259.1 - 0.0086 15.5 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein RsgA_GTPase PF03193.16 CBZ36259.1 - 0.0087 16.0 0.0 0.64 9.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase CdhD PF03599.16 CBZ36259.1 - 0.021 13.6 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit NOG1 PF06858.14 CBZ36259.1 - 0.029 14.1 0.3 0.063 13.1 0.3 1.6 1 1 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_18 PF13238.6 CBZ36259.1 - 0.036 14.6 0.0 0.07 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 CBZ36259.1 - 0.079 12.6 0.1 3.3 7.3 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DLIC PF05783.11 CBZ36259.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.3 1 1 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 CBZ36259.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Hemopexin PF00045.19 CBZ36261.1 - 0.11 12.4 0.8 1.9 8.5 0.0 3.2 3 0 0 3 3 3 0 Hemopexin CLP1_P PF16575.5 CBZ36263.1 - 3.1e-36 124.9 0.0 5.3e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 CBZ36263.1 - 0.0051 17.2 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 CBZ36263.1 - 0.028 14.6 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor PTH2 PF01981.16 CBZ36264.1 - 1.2e-20 73.9 0.3 1.6e-20 73.5 0.3 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 IL4_i_Ig PF18258.1 CBZ36264.1 - 0.06 13.6 0.1 0.095 12.9 0.1 1.3 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain TPR_9 PF13371.6 CBZ36266.1 - 0.00017 21.7 0.5 0.0032 17.6 0.8 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ36266.1 - 0.00099 19.0 0.2 0.47 10.7 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ36266.1 - 0.052 14.2 0.2 6.3 7.5 0.3 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ36266.1 - 0.1 12.9 0.0 0.67 10.3 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBZ36266.1 - 0.15 11.5 0.1 0.33 10.4 0.1 1.6 1 0 0 1 1 1 0 SHNi-TPR DUF2256 PF10013.9 CBZ36266.1 - 0.68 10.1 3.7 13 6.0 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DnaJ PF00226.31 CBZ36267.1 - 1.4e-11 44.3 0.0 3.9e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Plasmodium_Vir PF05795.11 CBZ36267.1 - 0.0033 16.9 2.7 0.0056 16.1 2.7 1.3 1 1 0 1 1 1 1 Plasmodium vivax Vir protein Dzip-like_N PF13815.6 CBZ36267.1 - 0.079 12.9 2.3 0.073 13.0 0.7 1.7 1 1 1 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal HSP70 PF00012.20 CBZ36268.1 - 9.3e-24 83.6 0.1 1e-23 83.4 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 CBZ36269.1 - 6.1e-220 731.4 2.6 6.9e-220 731.3 2.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ36269.1 - 1.9e-14 53.2 0.7 4.3e-13 48.8 0.3 2.4 2 1 0 2 2 2 1 MreB/Mbl protein StbA PF06406.11 CBZ36269.1 - 0.0024 17.2 1.3 0.8 8.9 0.1 3.5 3 1 1 4 4 4 2 StbA protein BcrAD_BadFG PF01869.20 CBZ36269.1 - 0.0055 16.2 0.3 3.5 7.1 0.0 2.5 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.16 CBZ36269.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Oleosin PF01277.17 CBZ36272.1 - 0.29 10.9 0.2 0.29 10.9 0.2 1.7 2 0 0 2 2 2 0 Oleosin HSP70 PF00012.20 CBZ36274.1 - 9.3e-24 83.6 0.1 1e-23 83.4 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 CBZ36275.1 - 2.7e-22 78.7 0.0 3.1e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein TSNAXIP1_N PF15739.5 CBZ36276.1 - 8.8e-06 26.1 0.4 8.8e-06 26.1 0.4 3.2 3 1 1 4 4 4 1 Translin-associated factor X-interacting N-terminus AAA_13 PF13166.6 CBZ36276.1 - 0.074 11.7 4.3 0.12 11.0 4.3 1.2 1 0 0 1 1 1 0 AAA domain SOGA PF11365.8 CBZ36276.1 - 8.6 7.6 11.9 5.7 8.1 7.2 3.2 4 0 0 4 4 4 0 Protein SOGA Cofilin_ADF PF00241.20 CBZ36277.1 - 2.1e-12 46.9 0.0 4.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein RecT PF03837.14 CBZ36277.1 - 0.032 13.7 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 RecT family Reticulon PF02453.17 CBZ36278.1 - 3.9e-27 95.2 7.2 4.8e-27 94.8 7.2 1.1 1 0 0 1 1 1 1 Reticulon PrgI PF12666.7 CBZ36278.1 - 0.0057 17.3 3.1 0.13 13.0 0.2 2.3 2 0 0 2 2 2 1 PrgI family protein DUF3292 PF11696.8 CBZ36278.1 - 0.0084 14.5 1.1 0.013 13.9 0.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3292) Sugarporin_N PF11471.8 CBZ36278.1 - 0.039 13.9 1.2 0.3 11.1 0.0 2.8 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension PRT_C PF08372.10 CBZ36278.1 - 0.085 12.6 3.2 0.28 10.9 0.3 2.2 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Cytomega_TRL10 PF06084.11 CBZ36278.1 - 0.15 12.1 0.7 0.36 10.8 0.7 1.7 1 1 0 1 1 1 0 Cytomegalovirus TRL10 protein CcmF_C PF16327.5 CBZ36278.1 - 0.65 9.2 7.7 0.45 9.8 0.7 2.0 1 1 1 2 2 2 0 Cytochrome c-type biogenesis protein CcmF C-terminal Phage_holin_3_6 PF07332.11 CBZ36278.1 - 4.5 7.4 9.8 1.9 8.6 1.1 2.3 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III FTHFS PF01268.19 CBZ36280.1 - 4.6e-254 843.8 0.0 5.2e-254 843.6 0.0 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase RRM_1 PF00076.22 CBZ36281.1 - 1e-15 57.2 0.0 2.2e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CBZ36281.1 - 0.0014 18.6 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3138 PF11336.8 CBZ36281.1 - 0.0095 14.6 2.0 0.014 14.0 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) PHM7_cyt PF14703.6 CBZ36281.1 - 0.05 13.8 0.4 13 6.0 0.4 2.1 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CPSF100_C PF13299.6 CBZ36281.1 - 0.056 13.6 0.6 0.081 13.1 0.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal AAA PF00004.29 CBZ36283.1 - 1.1e-13 51.8 0.0 2.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CBZ36283.1 - 1.3e-11 44.7 0.0 2.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBZ36283.1 - 1.6e-09 37.8 0.0 6.3e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase III, delta subunit AAA_11 PF13086.6 CBZ36283.1 - 1.2e-05 25.3 0.0 3.3e-05 23.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 CBZ36283.1 - 3.7e-05 24.0 0.1 0.00039 20.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CBZ36283.1 - 3.9e-05 23.4 0.0 0.0002 21.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ36283.1 - 4.6e-05 23.9 0.7 0.0011 19.4 0.0 2.6 2 1 0 3 3 3 1 AAA ATPase domain Rad17 PF03215.15 CBZ36283.1 - 0.00012 22.1 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain DUF2075 PF09848.9 CBZ36283.1 - 0.003 16.8 0.0 0.0041 16.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CBZ36283.1 - 0.0038 17.0 0.0 0.0071 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CBZ36283.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 CBZ36283.1 - 0.026 14.5 0.0 0.057 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBZ36283.1 - 0.041 14.0 0.0 0.082 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CBZ36283.1 - 0.043 13.2 0.1 0.1 11.9 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 CBZ36283.1 - 0.05 13.4 0.1 0.62 9.8 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_24 PF13479.6 CBZ36283.1 - 0.061 13.0 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CBZ36283.1 - 0.065 13.6 0.0 0.18 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 CBZ36283.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 CBZ36283.1 - 0.086 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CBZ36283.1 - 0.089 12.5 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 CBZ36283.1 - 0.18 11.7 0.0 0.89 9.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CBZ36283.1 - 0.26 11.8 0.0 0.39 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain ubiquitin PF00240.23 CBZ36286.1 - 2.4e-05 24.0 0.0 4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF4152 PF13680.6 CBZ36286.1 - 0.062 12.7 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4152) rRNA_methylase PF06962.12 CBZ36286.1 - 0.063 13.3 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative rRNA methylase TPR_12 PF13424.6 CBZ36287.1 - 8.5e-05 22.8 4.3 0.00039 20.7 0.8 2.7 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF3156 PF11354.8 CBZ36287.1 - 0.0021 18.0 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3156) TPR_10 PF13374.6 CBZ36287.1 - 0.13 12.2 1.1 8.3 6.4 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPT PF03151.16 CBZ36289.1 - 1.2e-15 57.6 20.3 1.5e-15 57.3 20.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBZ36289.1 - 0.00059 20.0 13.9 0.00059 20.0 13.9 2.3 2 1 0 2 2 2 2 EamA-like transporter family SH3_9 PF14604.6 CBZ36290.1 - 1.9e-06 27.6 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CBZ36290.1 - 6.8e-06 25.7 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CBZ36290.1 - 0.00018 21.0 0.0 0.00035 20.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain CortBP2 PF09727.9 CBZ36290.1 - 0.0038 17.2 0.3 0.0054 16.7 0.3 1.1 1 0 0 1 1 1 1 Cortactin-binding protein-2 Tmemb_9 PF05434.11 CBZ36290.1 - 0.31 10.9 0.7 0.51 10.2 0.7 1.3 1 0 0 1 1 1 0 TMEM9 LRR_6 PF13516.6 CBZ36291.1 - 0.0048 16.8 0.4 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Leucine Rich repeat GRAM PF02893.20 CBZ36293.1 - 2.1e-12 46.9 0.0 3.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 GRAM domain SPA PF08616.10 CBZ36294.1 - 1.1e-29 102.7 0.0 2.7e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 CBZ36294.1 - 9.6e-07 29.4 0.0 1.9e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 CBZ36294.1 - 0.00046 19.0 0.0 0.1 11.2 0.0 2.4 1 1 1 2 2 2 2 Transport protein Avl9 DENN PF02141.21 CBZ36294.1 - 0.0051 16.8 0.7 0.01 15.8 0.1 1.9 2 1 0 2 2 2 1 DENN (AEX-3) domain DUF2347 PF09804.9 CBZ36294.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) TPR_1 PF00515.28 CBZ36295.1 - 1.8e-26 90.8 8.4 1.6e-08 34.0 1.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ36295.1 - 3.2e-19 67.4 14.1 3.6e-07 29.8 0.0 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ36295.1 - 9.8e-16 56.6 3.6 5.6e-05 23.0 0.7 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ36295.1 - 1.7e-13 50.0 9.5 3.4e-07 29.9 0.7 3.8 2 1 2 4 4 4 3 TPR repeat TPR_17 PF13431.6 CBZ36295.1 - 5.6e-11 42.0 3.2 0.00044 20.4 0.3 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ36295.1 - 1.3e-08 35.0 3.4 2.3e-05 24.6 0.2 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ36295.1 - 1.9e-08 34.4 0.5 0.049 14.5 0.0 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ36295.1 - 6.6e-08 33.1 7.9 7.8e-05 23.2 0.0 3.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ36295.1 - 2.1e-07 30.5 0.5 0.072 13.2 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat SGT1 PF07093.11 CBZ36295.1 - 4e-07 28.9 1.3 5.7e-07 28.4 1.3 1.2 1 0 0 1 1 1 1 SGT1 protein STI1 PF17830.1 CBZ36295.1 - 7.9e-06 25.7 9.7 0.00094 19.1 0.3 3.3 3 0 0 3 3 2 2 STI1 domain TPR_9 PF13371.6 CBZ36295.1 - 3.5e-05 23.9 0.1 0.0083 16.2 0.1 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ36295.1 - 7.1e-05 22.5 2.2 5.4 7.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ36295.1 - 7.3e-05 23.2 4.9 0.028 14.9 0.5 3.8 3 1 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ36295.1 - 0.0036 17.9 4.9 1.7 9.5 0.0 4.0 5 0 0 5 5 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ36295.1 - 0.019 15.1 2.6 15 5.8 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CBZ36295.1 - 0.026 14.7 3.8 0.33 11.2 0.5 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TOM20_plant PF06552.12 CBZ36295.1 - 0.026 14.3 2.5 1.1 9.0 0.5 3.2 1 1 1 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 Ins_allergen_rp PF06757.13 CBZ36295.1 - 0.079 12.9 0.9 3 7.8 0.0 2.9 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification MIT PF04212.18 CBZ36295.1 - 0.39 10.8 10.9 2.3 8.3 1.7 3.8 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain Smg4_UPF3 PF03467.15 CBZ36295.1 - 0.89 9.5 5.7 0.27 11.2 1.1 2.4 3 0 0 3 3 3 0 Smg-4/UPF3 family RIG-I_C PF18119.1 CBZ36295.1 - 1.4 9.0 4.6 2.5 8.1 1.6 2.6 2 1 1 3 3 3 0 RIG-I receptor C-terminal domain Methyltransf_5 PF01795.19 CBZ36296.1 - 0.021 14.3 0.3 0.031 13.8 0.3 1.2 1 0 0 1 1 1 0 MraW methylase family DSBA PF01323.20 CBZ36296.1 - 0.045 13.5 0.4 0.071 12.9 0.4 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain TMA7 PF09072.10 CBZ36297.1 - 2.8e-14 53.7 13.1 3e-14 53.6 13.1 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 FixG_C PF11614.8 CBZ36298.1 - 0.0058 16.9 0.2 0.0092 16.2 0.2 1.5 1 1 0 1 1 1 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Sod_Fe_N PF00081.22 CBZ36299.1 - 1.7e-06 28.4 0.0 2.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 CBZ36299.1 - 2.6e-06 27.6 0.0 6e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain zf-CCCH PF00642.24 CBZ36300.1 - 1.9e-06 27.6 1.7 1.9e-06 27.6 1.7 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ36300.1 - 2.1e-05 24.4 4.5 4.9e-05 23.2 4.5 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBZ36300.1 - 4.3e-05 23.2 2.5 7.8e-05 22.4 2.5 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CBZ36300.1 - 0.082 13.4 1.9 0.18 12.3 1.9 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF3489 PF11994.8 CBZ36300.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) DUF872 PF05915.12 CBZ36301.1 - 1.2e-06 28.7 0.6 1.6e-06 28.3 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Cpn60_TCP1 PF00118.24 CBZ36304.1 - 2.4e-71 240.8 6.8 1.1e-70 238.6 6.8 1.8 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RabGAP-TBC PF00566.18 CBZ36306.1 - 8.4e-34 117.1 0.7 3.4e-33 115.1 0.7 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PPR PF01535.20 CBZ36311.1 - 0.00091 19.3 0.4 67 4.1 0.0 5.7 7 0 0 7 7 7 0 PPR repeat PPR_2 PF13041.6 CBZ36311.1 - 0.0016 18.6 0.0 55 4.1 0.0 5.1 5 0 0 5 5 5 0 PPR repeat family TPR_7 PF13176.6 CBZ36311.1 - 0.0036 17.2 2.9 65 3.9 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ36311.1 - 0.052 14.4 8.9 43 5.3 0.0 6.7 5 1 1 6 6 6 0 Tetratricopeptide repeat OST_P2 PF18235.1 CBZ36312.1 - 0.12 12.3 0.0 2.5 8.1 0.0 2.4 3 0 0 3 3 3 0 Oligosaccharyltransferase Peripheral 2 domain Aldedh PF00171.22 CBZ36313.1 - 4.2e-119 398.1 0.0 5.4e-119 397.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Med27 PF11571.8 CBZ36313.1 - 0.13 12.7 0.0 0.32 11.4 0.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 27 Pkinase PF00069.25 CBZ36314.1 - 2.3e-52 178.0 0.0 3.3e-52 177.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36314.1 - 1.3e-17 64.0 0.0 1.7e-17 63.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBZ36314.1 - 1.2e-06 28.1 0.1 1.8e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ36314.1 - 0.0004 20.4 0.2 0.00057 19.9 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ36314.1 - 0.0055 16.1 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ36314.1 - 0.0071 15.2 0.1 0.011 14.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase PI-PLC-X PF00388.19 CBZ36318.1 - 1.8e-59 199.5 0.0 4e-59 198.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBZ36318.1 - 2.5e-33 114.8 0.0 4.7e-33 113.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CBZ36318.1 - 2.5e-17 63.0 0.1 1.4e-16 60.7 0.1 2.3 2 0 0 2 2 2 1 C2 domain EF-hand_7 PF13499.6 CBZ36318.1 - 3.6e-10 40.2 0.5 2.5e-06 27.8 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ36318.1 - 5.1e-09 35.1 0.0 0.0022 17.4 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CBZ36318.1 - 1.3e-06 27.9 0.1 0.45 10.6 0.1 4.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CBZ36318.1 - 2.4e-06 26.8 0.7 0.013 15.0 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CBZ36318.1 - 5.4e-06 26.2 2.6 0.0062 16.4 0.2 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_10 PF14788.6 CBZ36318.1 - 2.8e-05 23.9 0.1 5.9e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 EF hand GDPD PF03009.17 CBZ36318.1 - 0.0074 16.0 0.2 0.024 14.4 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family ATG13 PF10033.9 CBZ36318.1 - 0.014 15.1 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Autophagy-related protein 13 EF-hand_4 PF12763.7 CBZ36318.1 - 0.042 13.8 0.4 0.31 11.0 0.4 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand zf-CHCC PF10276.9 CBZ36319.1 - 6.3e-05 23.0 1.9 6.3e-05 23.0 1.9 1.9 2 0 0 2 2 2 1 Zinc-finger domain Gp_dh_C PF02800.20 CBZ36320.1 - 1.1e-64 216.7 0.1 1.9e-64 216.0 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBZ36320.1 - 2.8e-30 104.6 0.1 5.8e-30 103.6 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 CBZ36320.1 - 0.019 15.8 0.1 0.036 14.9 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Gp_dh_C PF02800.20 CBZ36321.1 - 1.1e-64 216.7 0.1 1.9e-64 216.0 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBZ36321.1 - 2.8e-30 104.6 0.1 5.8e-30 103.6 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 CBZ36321.1 - 0.019 15.8 0.1 0.036 14.9 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DUF2817 PF10994.8 CBZ36322.1 - 1.8e-107 359.7 0.3 2.1e-107 359.5 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) AstE_AspA PF04952.14 CBZ36322.1 - 3.3e-05 23.1 0.0 6.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family TPR_1 PF00515.28 CBZ36324.1 - 1.5e-106 344.3 35.8 4.5e-08 32.6 0.5 14.8 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ36324.1 - 9.2e-87 278.3 48.3 3.2e-06 26.8 0.5 15.3 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ36324.1 - 7.7e-66 217.5 31.9 1.2e-09 37.7 3.0 14.0 4 3 10 14 14 14 12 TPR repeat TPR_8 PF13181.6 CBZ36324.1 - 3.9e-62 201.4 22.0 6.8e-05 22.8 0.3 14.5 15 0 0 15 15 15 11 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ36324.1 - 2.1e-50 169.1 55.4 9.3e-10 39.0 0.2 10.2 8 2 2 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ36324.1 - 8.6e-46 151.1 25.8 5.5e-06 26.4 0.0 12.9 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ36324.1 - 1.1e-40 137.6 42.2 1.1e-05 25.5 0.2 11.0 4 3 6 11 11 11 9 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ36324.1 - 3.1e-36 123.5 57.5 3.2e-08 33.7 4.7 11.0 5 2 6 12 12 12 10 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ36324.1 - 2.4e-29 99.2 34.5 0.0049 16.8 0.1 14.0 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ36324.1 - 4.4e-22 77.2 41.3 0.088 13.5 0.2 14.2 15 0 0 15 15 14 6 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ36324.1 - 6.9e-20 71.3 28.1 5.7e-05 23.5 0.1 9.6 6 4 4 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ36324.1 - 6.3e-19 67.1 44.6 0.0083 16.9 0.1 14.3 4 2 11 15 15 14 6 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ36324.1 - 1.1e-10 41.0 46.6 0.43 10.5 0.2 12.3 13 0 0 13 13 13 5 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBZ36324.1 - 5.3e-09 35.4 29.8 1.3 8.5 0.0 10.9 13 0 0 13 13 12 4 SHNi-TPR ANAPC3 PF12895.7 CBZ36324.1 - 2.8e-06 27.5 30.9 0.0054 16.9 0.7 7.2 4 4 4 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 CBZ36324.1 - 4.1e-05 23.6 27.2 0.088 12.9 0.1 9.3 9 1 0 9 9 9 2 MIT (microtubule interacting and transport) domain Coatomer_E PF04733.14 CBZ36324.1 - 0.00087 18.8 0.4 6.3 6.1 0.0 4.1 4 1 0 4 4 4 1 Coatomer epsilon subunit DUF3856 PF12968.7 CBZ36324.1 - 0.011 15.8 15.7 14 5.7 0.2 8.0 7 4 1 9 9 8 0 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 CBZ36324.1 - 0.018 15.1 2.1 14 5.9 0.1 4.7 4 2 0 4 4 4 0 Anaphase-promoting complex subunit 5 PA28_beta PF02252.18 CBZ36324.1 - 0.041 13.5 4.0 8 6.1 0.0 4.7 5 0 0 5 5 5 0 Proteasome activator pa28 beta subunit NARP1 PF12569.8 CBZ36324.1 - 0.042 12.8 11.4 0.17 10.7 0.1 4.8 2 1 3 6 6 6 0 NMDA receptor-regulated protein 1 BTAD PF03704.17 CBZ36324.1 - 0.067 13.6 32.7 0.68 10.4 0.7 6.7 4 2 3 7 7 7 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 CBZ36324.1 - 0.94 9.8 15.4 14 6.1 0.0 6.2 6 2 0 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ36324.1 - 3.5 8.5 24.3 4.5 8.2 1.4 8.4 8 0 0 8 8 8 0 Tetratricopeptide repeat LSM PF01423.22 CBZ36325.1 - 3.3e-08 33.1 0.3 4.8e-08 32.6 0.3 1.3 1 0 0 1 1 1 1 LSM domain KH_8 PF17903.1 CBZ36326.1 - 8.1e-26 89.9 0.0 1.6e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain DUF1513 PF07433.11 CBZ36327.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1513) DUF21 PF01595.20 CBZ36328.1 - 9.2e-27 93.9 4.2 3.2e-26 92.1 4.8 1.6 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CBZ36328.1 - 0.00034 21.0 0.0 0.47 10.9 0.0 2.8 3 0 0 3 3 3 2 CBS domain eIF-3_zeta PF05091.12 CBZ36329.1 - 3.4e-91 306.8 0.0 4e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.25 CBZ36330.1 - 3.2e-66 223.4 0.0 4.5e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36330.1 - 6.1e-45 153.5 0.0 9.4e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ36330.1 - 0.0027 16.6 0.0 0.0053 15.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ36330.1 - 0.0035 16.7 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CBZ36330.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MCLC PF05934.11 CBZ36330.1 - 0.52 9.0 2.1 1.1 7.9 2.1 1.4 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Kinesin PF00225.23 CBZ36331.1 - 1.5e-82 277.2 0.0 1.5e-82 277.2 0.0 2.9 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ36331.1 - 3.1e-20 72.7 0.1 2.3e-19 69.8 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 CBZ36331.1 - 0.0033 17.2 1.0 0.0033 17.2 1.0 7.7 8 0 0 8 8 8 1 Coiled-coil N-terminus of cGMP-dependent protein kinase tRNA_m1G_MT PF01746.21 CBZ36332.1 - 1e-18 67.7 0.0 2.1e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase GHMP_kinases_N PF00288.26 CBZ36333.1 - 4.1e-09 36.6 1.7 1e-08 35.2 1.7 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CBZ36333.1 - 5.5e-07 29.9 0.1 1.2e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Bac_rhamnosid_C PF17390.2 CBZ36333.1 - 0.056 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain PPR_3 PF13812.6 CBZ36335.1 - 0.0027 17.8 0.0 0.24 11.5 0.0 3.7 5 0 0 5 5 5 1 Pentatricopeptide repeat domain MOZART2 PF12926.7 CBZ36335.1 - 0.067 12.8 0.1 0.51 10.0 0.0 2.5 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated SAM_decarbox PF01536.16 CBZ36336.1 - 5e-88 295.5 0.0 5.8e-88 295.3 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase SAM_decarbox PF01536.16 CBZ36337.1 - 1.6e-09 37.3 0.0 0.00039 19.6 0.0 2.1 2 0 0 2 2 2 2 Adenosylmethionine decarboxylase tRNA-synt_1 PF00133.22 CBZ36338.1 - 2.2e-195 650.4 0.0 2.5e-194 646.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CBZ36338.1 - 6.7e-37 126.8 0.0 1.3e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Val_tRNA-synt_C PF10458.9 CBZ36338.1 - 4.4e-15 55.7 1.2 9.2e-15 54.7 1.2 1.6 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1g PF09334.11 CBZ36338.1 - 1e-14 54.1 0.3 1.5e-07 30.5 0.0 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CBZ36338.1 - 2.3e-08 33.8 0.0 0.00017 21.2 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CBZ36338.1 - 0.022 14.1 0.8 1.2 8.4 0.1 3.2 4 0 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 CBZ36338.1 - 0.052 12.9 0.2 0.12 11.7 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) ADC PF06314.11 CBZ36338.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) MIS13 PF08202.11 CBZ36338.1 - 0.15 11.3 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Nuc_recep-AF1 PF11825.8 CBZ36339.1 - 0.077 13.0 0.2 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 GH-E PF14410.6 CBZ36339.1 - 0.34 11.3 2.1 0.68 10.4 2.1 1.5 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues TRAP_beta PF05753.14 CBZ36340.1 - 1.8e-09 37.3 3.0 2.7e-08 33.4 3.0 2.5 1 1 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.18 CBZ36340.1 - 3e-09 37.0 2.7 9.7e-09 35.4 2.7 1.9 1 1 0 1 1 1 1 Domain of unknown function DUF11 CARDB PF07705.11 CBZ36340.1 - 1e-05 25.7 0.9 1.5e-05 25.2 0.9 1.3 1 0 0 1 1 1 1 CARDB NPCBM_assoc PF10633.9 CBZ36340.1 - 0.0031 17.7 0.6 0.018 15.3 0.3 2.3 1 1 0 1 1 1 1 NPCBM-associated, NEW3 domain of alpha-galactosidase TPH PF13868.6 CBZ36342.1 - 1.1e-36 126.1 142.6 1.1e-36 126.1 142.6 1.8 1 1 0 1 1 1 1 Trichohyalin-plectin-homology domain RRM_1 PF00076.22 CBZ36343.1 - 1.4e-08 34.4 0.0 2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ36343.1 - 0.094 12.3 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG-CoA_red PF00368.18 CBZ36344.1 - 1.9e-133 445.0 3.5 2.2e-133 444.8 3.5 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Ribosomal_S26e PF01283.19 CBZ36345.1 - 3.7e-35 120.6 3.4 3.9e-35 120.5 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e TPR_MLP1_2 PF07926.12 CBZ36346.1 - 0.0063 16.6 2.2 0.0063 16.6 2.2 5.0 3 2 0 3 3 3 1 TPR/MLP1/MLP2-like protein DUF2274 PF10038.9 CBZ36346.1 - 0.094 13.2 4.8 0.042 14.3 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) LPP PF04728.13 CBZ36346.1 - 0.54 10.7 4.3 2.1 8.8 0.3 3.6 3 0 0 3 3 3 0 Lipoprotein leucine-zipper DUF4250 PF14056.6 CBZ36346.1 - 0.92 9.5 3.9 0.95 9.5 0.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4250) tRNA-synt_1c PF00749.21 CBZ36350.1 - 6.6e-104 347.2 0.1 9.4e-104 346.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CBZ36350.1 - 2.7e-35 121.8 0.2 5.9e-35 120.7 0.2 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain HA2 PF04408.23 CBZ36351.1 - 5.7e-14 52.3 0.0 5.7e-14 52.3 0.0 3.0 2 1 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ36351.1 - 1.1e-10 41.9 0.1 9.6e-10 38.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ36351.1 - 5.1e-09 36.1 0.0 2e-07 30.9 0.0 2.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ36351.1 - 1.5e-06 28.5 0.6 4.8e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 CBZ36351.1 - 2.6e-06 27.7 0.0 5.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 CBZ36351.1 - 0.00048 20.5 0.0 0.002 18.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CBZ36351.1 - 0.0037 17.3 3.3 0.028 14.4 0.1 3.4 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit ATPase PF06745.13 CBZ36351.1 - 0.013 14.9 0.1 0.14 11.4 0.0 2.5 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 CBZ36351.1 - 0.022 13.8 4.9 0.053 12.6 4.9 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 CBZ36351.1 - 0.12 12.7 2.8 0.4 11.1 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain BRCT PF00533.26 CBZ36351.1 - 0.14 12.5 0.0 0.86 10.0 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF4890 PF16231.5 CBZ36351.1 - 0.18 12.3 19.3 0.51 10.8 19.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) AAA_23 PF13476.6 CBZ36351.1 - 1 9.8 0.0 1 9.8 0.0 3.3 3 1 0 3 3 2 0 AAA domain Ank_4 PF13637.6 CBZ36352.1 - 1.7e-33 114.5 4.8 4.1e-10 40.0 0.0 6.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ36352.1 - 1.9e-32 111.7 2.5 1.9e-11 44.4 0.0 4.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ36352.1 - 2.2e-26 89.0 3.0 0.00075 19.8 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 CBZ36352.1 - 4.3e-25 87.4 6.6 1.3e-07 31.7 0.0 6.6 4 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 CBZ36352.1 - 2e-24 84.9 8.4 0.00021 21.6 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat DUF3417 PF11897.8 CBZ36352.1 - 0.074 13.5 0.6 0.19 12.2 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) Reductase_C PF14759.6 CBZ36352.1 - 0.1 13.2 0.0 0.52 10.9 0.0 2.2 2 0 0 2 2 2 0 Reductase C-terminal FlgN PF05130.12 CBZ36352.1 - 3.8 8.0 11.0 0.97 9.9 0.1 3.4 3 1 0 3 3 3 0 FlgN protein Sensor PF13796.6 CBZ36353.1 - 0.042 13.9 2.0 0.058 13.5 2.0 1.2 1 0 0 1 1 1 0 Putative sensor Metallophos PF00149.28 CBZ36354.1 - 3.6e-09 37.4 0.1 5.6e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase XPC-binding PF09280.11 CBZ36356.1 - 3.5e-14 52.3 0.1 7.2e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 CBZ36356.1 - 1.6e-13 50.2 0.0 3.1e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CBZ36356.1 - 1.3e-11 44.2 4.9 4.4e-07 29.7 0.8 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.8 CBZ36356.1 - 4e-07 29.8 0.1 2.4e-06 27.3 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 CBZ36356.1 - 0.031 14.1 0.0 0.088 12.6 0.0 1.7 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain YukD PF08817.10 CBZ36356.1 - 0.1 13.3 0.0 0.28 11.9 0.0 1.9 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_4 PF18036.1 CBZ36356.1 - 0.25 11.4 0.3 6.1 7.0 0.1 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain MORN PF02493.20 CBZ36357.1 - 6.3e-92 296.3 107.3 3e-10 39.4 2.5 15.1 15 0 0 15 15 15 15 MORN repeat Peptidase_S55 PF05580.12 CBZ36357.1 - 0.072 13.0 9.8 1.3 8.9 0.1 5.3 3 2 2 5 5 5 0 SpoIVB peptidase S55 MORN_2 PF07661.13 CBZ36357.1 - 4 8.0 16.9 31 5.3 0.3 6.8 4 1 2 6 6 6 0 MORN repeat variant BAR PF03114.18 CBZ36358.1 - 0.00026 20.7 0.3 0.00036 20.2 0.3 1.2 1 0 0 1 1 1 1 BAR domain Ribosomal_L6 PF00347.23 CBZ36360.1 - 7.4e-16 58.6 0.7 9e-16 58.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L6 Glyco_hydro_65C PF03633.15 CBZ36360.1 - 0.082 12.8 0.3 15 5.6 0.0 2.7 3 0 0 3 3 3 0 Glycosyl hydrolase family 65, C-terminal domain EF-hand_7 PF13499.6 CBZ36362.1 - 8.4e-39 131.9 15.9 2.9e-08 34.1 0.2 6.2 6 0 0 6 6 6 5 EF-hand domain pair EF-hand_1 PF00036.32 CBZ36362.1 - 1.3e-34 115.1 13.8 5.3e-05 22.5 0.0 10.6 10 0 0 10 10 10 7 EF hand EF-hand_6 PF13405.6 CBZ36362.1 - 1.8e-33 111.6 13.3 1.2e-05 24.9 0.1 10.2 10 0 0 10 10 10 7 EF-hand domain EF-hand_5 PF13202.6 CBZ36362.1 - 1.1e-27 94.2 13.1 4.5e-05 22.8 0.1 8.7 9 0 0 9 9 9 6 EF hand EF-hand_8 PF13833.6 CBZ36362.1 - 3.2e-16 58.9 17.6 0.19 11.6 0.2 10.7 10 1 1 11 11 11 7 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CBZ36362.1 - 3.5e-10 40.2 0.9 0.02 15.2 0.0 5.5 4 2 1 5 5 5 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CBZ36362.1 - 0.048 13.5 0.1 30 4.6 0.0 3.7 3 0 0 3 3 3 0 EF hand Caleosin PF05042.13 CBZ36362.1 - 0.076 12.9 1.6 14 5.5 0.0 4.8 6 0 0 6 6 6 0 Caleosin related protein Tropomyosin PF00261.20 CBZ36362.1 - 0.098 12.0 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Tropomyosin RelB_N PF18506.1 CBZ36362.1 - 0.15 11.9 0.2 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 RelB Antitoxin alpha helical domain DUF3349 PF11829.8 CBZ36362.1 - 0.21 12.4 1.8 15 6.4 0.1 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF3349) PGK PF00162.19 CBZ36364.1 - 5e-136 453.6 0.1 6.2e-136 453.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase PAS PF00989.25 CBZ36364.1 - 6.1e-07 29.4 0.0 2.6e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 CBZ36364.1 - 0.00015 22.0 0.0 0.00089 19.5 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 CBZ36364.1 - 0.00035 20.8 0.0 0.0055 16.9 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.7 CBZ36364.1 - 0.00091 19.2 0.0 0.0029 17.6 0.0 1.9 1 0 0 1 1 1 1 PAS domain DUF2671 PF10877.8 CBZ36364.1 - 0.051 13.4 0.2 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2671) CAS_CSE1 PF03378.15 CBZ36365.1 - 2.8e-68 230.5 0.0 7.9e-68 229.0 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 CBZ36365.1 - 4.6e-47 160.6 0.0 6.9e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 CBZ36365.1 - 0.0035 17.2 0.0 0.027 14.4 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CBZ36365.1 - 0.013 15.6 1.3 2.2 8.3 0.1 3.8 3 1 0 3 3 3 0 Exportin 1-like protein MCM_N PF14551.6 CBZ36365.1 - 0.11 13.1 0.7 2.5 8.7 0.1 3.1 3 0 0 3 3 3 0 MCM N-terminal domain Dynein_heavy PF03028.15 CBZ36367.1 - 8.6e-07 29.1 0.0 2.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain WD40 PF00400.32 CBZ36367.1 - 1e-05 26.1 9.6 1.8 9.6 0.5 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Tcp11 PF05794.13 CBZ36368.1 - 9.9e-30 104.0 3.8 9.9e-30 104.0 3.8 1.6 2 0 0 2 2 2 1 T-complex protein 11 MKT1_C PF12246.8 CBZ36369.1 - 4.1e-17 62.2 0.0 6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CBZ36369.1 - 5.2e-08 33.1 0.0 1.6e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication DNA_ligase_A_M PF01068.21 CBZ36370.1 - 1.5e-55 188.0 0.0 2.3e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CBZ36370.1 - 2.2e-32 112.7 0.0 3.5e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CBZ36370.1 - 1.5e-23 83.2 0.0 3.1e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CBZ36370.1 - 1.8e-05 25.1 0.0 3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 CBZ36370.1 - 0.085 12.9 0.5 3 7.9 0.0 2.5 2 0 0 2 2 2 0 DNA ligase OB-like domain TPR_16 PF13432.6 CBZ36372.1 - 2.9e-08 34.2 7.5 0.0012 19.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ36372.1 - 2.1e-05 24.9 9.7 0.042 14.7 0.0 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ36372.1 - 6.1e-05 23.1 1.4 26 5.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ36372.1 - 0.00017 21.7 6.5 0.013 15.6 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ36372.1 - 0.0015 18.2 5.0 5 7.1 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ36372.1 - 0.0033 17.4 12.5 0.051 13.7 0.0 5.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ36372.1 - 0.0058 17.1 6.2 0.018 15.5 0.1 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ36372.1 - 0.013 15.8 0.2 0.16 12.2 0.2 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CBZ36372.1 - 0.017 14.8 1.9 22 4.8 0.0 4.2 5 0 0 5 5 5 0 TPR repeat TTC5_OB PF16669.5 CBZ36372.1 - 0.018 14.8 0.2 0.2 11.4 0.2 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain ChAPs PF09295.10 CBZ36372.1 - 0.19 10.7 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_8 PF13181.6 CBZ36372.1 - 2.5 8.5 4.6 49 4.5 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Yippee-Mis18 PF03226.14 CBZ36373.1 - 2e-11 44.0 0.2 2.6e-11 43.7 0.2 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 CBZ36373.1 - 0.002 18.3 0.2 0.0028 17.9 0.2 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I Pkinase PF00069.25 CBZ36374.1 - 1.3e-21 77.2 0.0 1.6e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36374.1 - 2.2e-11 43.5 0.0 2.7e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ36374.1 - 2.2e-09 36.6 0.0 3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ36374.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ36374.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-MIZ PF02891.20 CBZ36376.1 - 7.4e-19 67.2 5.3 1.3e-18 66.4 5.3 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CBZ36376.1 - 3.8e-05 23.4 1.4 7.9e-05 22.4 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit PWWP PF00855.17 CBZ36376.1 - 0.001 19.4 0.1 0.002 18.5 0.1 1.5 1 0 0 1 1 1 1 PWWP domain CYLD_phos_site PF16607.5 CBZ36376.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphorylation region of CYLD, unstructured S-AdoMet_synt_C PF02773.16 CBZ36377.1 - 4.8e-66 220.9 0.0 9.3e-66 220.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CBZ36377.1 - 8.6e-43 145.4 0.0 1.3e-41 141.6 0.0 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CBZ36377.1 - 1.3e-40 138.1 1.1 1.5e-40 137.9 0.2 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Strep_pep PF14404.6 CBZ36377.1 - 0.029 14.6 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species Rhodanese PF00581.20 CBZ36378.1 - 1.5e-06 28.7 0.0 2.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 CBZ36379.1 - 1.5e-06 28.7 0.0 2.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 CBZ36380.1 - 1.5e-06 28.7 0.0 2.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain RF-1 PF00472.20 CBZ36381.1 - 6.3e-08 32.6 0.8 1.7e-07 31.2 0.1 2.0 3 0 0 3 3 3 1 RF-1 domain CARD PF00619.21 CBZ36381.1 - 0.0057 16.7 0.1 0.019 15.0 0.1 1.9 1 0 0 1 1 1 1 Caspase recruitment domain Terminase_4 PF05119.12 CBZ36381.1 - 0.033 14.6 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 Phage terminase, small subunit p450 PF00067.22 CBZ36382.1 - 4.9e-49 167.3 0.0 6.9e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Mago_nashi PF02792.14 CBZ36383.1 - 7.3e-59 198.0 0.2 8.3e-59 197.8 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein zf-CCCH PF00642.24 CBZ36384.1 - 5.6e-06 26.1 1.6 1.2e-05 25.0 1.6 1.6 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ36384.1 - 0.49 10.5 5.7 0.15 12.1 0.8 2.1 2 0 0 2 2 2 0 Zinc finger domain Pkinase PF00069.25 CBZ36385.1 - 1.9e-34 119.2 0.0 1.2e-17 64.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36385.1 - 4.5e-10 39.3 0.0 1e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase DAHP_snth_FXD PF18152.1 CBZ36385.1 - 0.36 10.7 1.2 0.78 9.6 0.1 2.1 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Ribosomal_S11 PF00411.19 CBZ36386.1 - 3.4e-47 159.4 1.6 4.3e-47 159.1 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 NFACT-R_1 PF05670.13 CBZ36386.1 - 0.1 13.2 0.0 0.14 12.8 0.0 1.2 1 0 0 1 1 1 0 NFACT protein RNA binding domain ATP-synt_DE_N PF02823.16 CBZ36387.1 - 5.1e-13 48.7 0.0 9.7e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF773 PF05600.12 CBZ36388.1 - 8e-19 67.7 13.2 9.2e-13 47.7 2.5 3.3 1 1 2 3 3 3 3 CDK5 regulatory subunit-associated protein 3 Q_salvage PF10343.9 CBZ36388.1 - 0.0076 15.9 0.5 0.016 14.8 0.5 1.5 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Cytochrom_B562 PF07361.11 CBZ36388.1 - 0.026 15.2 3.3 0.18 12.5 0.3 2.6 2 0 0 2 2 2 0 Cytochrome b562 Rep_3 PF01051.21 CBZ36388.1 - 0.032 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Initiator Replication protein CENP-H PF05837.12 CBZ36388.1 - 0.042 14.3 8.0 0.15 12.4 0.1 2.9 2 1 0 2 2 2 0 Centromere protein H (CENP-H) SOAR PF16533.5 CBZ36388.1 - 0.1 12.6 0.5 0.1 12.6 0.5 2.8 2 1 0 2 2 2 0 STIM1 Orai1-activating region ABC_tran_CTD PF16326.5 CBZ36388.1 - 0.28 11.5 6.3 8.4 6.7 0.3 3.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain Prefoldin_2 PF01920.20 CBZ36388.1 - 0.37 10.8 5.1 11 6.0 0.3 2.7 2 0 0 2 2 2 0 Prefoldin subunit ZapB PF06005.12 CBZ36388.1 - 5.6 7.5 7.5 0.26 11.8 0.6 2.3 3 0 0 3 3 3 0 Cell division protein ZapB TSNAXIP1_N PF15739.5 CBZ36388.1 - 8.4 6.8 9.6 1.4 9.3 1.1 3.1 2 1 0 3 3 3 0 Translin-associated factor X-interacting N-terminus Cyclin PF08613.11 CBZ36390.1 - 2.8e-21 76.6 0.1 3.7e-21 76.2 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBZ36390.1 - 1.3e-05 24.9 0.2 2.3e-05 24.2 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain LRR_9 PF14580.6 CBZ36391.1 - 3.5e-20 72.2 0.4 1.4e-14 54.0 0.0 2.5 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CBZ36391.1 - 1.1e-11 44.8 15.6 0.0001 22.6 1.2 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ36391.1 - 2.4e-09 36.8 30.3 1e-05 25.2 4.7 3.8 1 1 3 4 4 4 4 Leucine rich repeat DpaA_N PF16924.5 CBZ36391.1 - 0.058 13.5 0.0 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain LRR_6 PF13516.6 CBZ36391.1 - 6.8 7.0 7.0 64 4.0 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Ribosomal_L15e PF00827.17 CBZ36392.1 - 1.7e-85 285.6 7.4 2e-85 285.3 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 ATP-synt_C PF00137.21 CBZ36393.1 - 2.2e-21 75.9 42.9 9e-12 45.2 12.6 3.1 3 0 0 3 3 3 2 ATP synthase subunit C SnoaL_2 PF12680.7 CBZ36394.1 - 5.1e-05 23.8 0.1 9.7e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_3 PF13474.6 CBZ36394.1 - 0.00032 21.0 0.2 0.00074 19.8 0.1 1.7 2 1 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 CBZ36394.1 - 0.0034 17.2 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 CBZ36394.1 - 0.0039 17.6 0.0 0.02 15.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) KfrB PF18790.1 CBZ36395.1 - 0.18 12.1 1.5 7.1 7.0 0.0 2.9 2 0 0 2 2 2 0 KfrB protein DUF3808 PF10300.9 CBZ36396.1 - 2.7e-26 92.3 4.1 4.1e-25 88.5 3.6 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 CBZ36396.1 - 7e-11 42.3 0.6 9.7e-06 25.8 0.2 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ36396.1 - 4.2e-08 32.7 6.1 0.054 13.6 0.4 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ36396.1 - 1.6e-05 25.4 0.5 1.2 9.7 0.1 5.1 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ36396.1 - 5.6e-05 23.6 0.4 0.98 10.4 0.1 5.0 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ36396.1 - 0.00011 21.8 0.1 2.3 8.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ36396.1 - 0.00017 21.7 2.9 0.55 10.5 1.0 4.6 4 2 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBZ36396.1 - 0.0049 17.4 5.1 6.7 7.6 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CBZ36396.1 - 0.042 13.2 0.0 2.7 7.3 0.0 2.8 3 0 0 3 3 3 0 MalT-like TPR region TPR_16 PF13432.6 CBZ36396.1 - 0.064 13.9 2.9 1.8 9.3 0.6 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat SR-25 PF10500.9 CBZ36396.1 - 0.082 12.5 6.6 0.14 11.7 6.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2225 PF09986.9 CBZ36396.1 - 0.18 11.5 5.8 0.6 9.8 1.4 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF4710 PF15828.5 CBZ36396.1 - 0.76 9.9 7.6 1.9 8.7 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Cytochrome-c551 PF10643.9 CBZ36397.1 - 1.5 8.3 5.7 0.34 10.5 0.8 2.3 3 0 0 3 3 3 0 Photosystem P840 reaction-centre cytochrome c-551 CPSF_A PF03178.15 CBZ36398.1 - 2.5e-67 227.5 0.0 4.5e-67 226.7 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CBZ36398.1 - 3.9e-06 25.8 0.0 1.5e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_60s PF00428.19 CBZ36399.1 - 3.2e-24 85.3 15.1 3.7e-24 85.1 15.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2275 PF10039.9 CBZ36399.1 - 0.031 14.4 1.1 0.037 14.1 1.1 1.0 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) TetR_C_31 PF17940.1 CBZ36399.1 - 0.086 13.0 5.5 0.13 12.5 4.4 1.8 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_60s PF00428.19 CBZ36400.1 - 3.2e-24 85.3 15.1 3.7e-24 85.1 15.1 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2275 PF10039.9 CBZ36400.1 - 0.031 14.4 1.1 0.037 14.1 1.1 1.0 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) TetR_C_31 PF17940.1 CBZ36400.1 - 0.086 13.0 5.5 0.13 12.5 4.4 1.8 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ATP_bind_1 PF03029.17 CBZ36401.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Meth_synt_2 PF01717.18 CBZ36402.1 - 8.4e-155 514.9 0.0 1.8e-147 490.8 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CBZ36402.1 - 2e-120 402.0 0.0 4e-111 371.5 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain MIP PF00230.20 CBZ36403.1 - 8.2e-48 163.1 9.6 1e-47 162.7 9.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein RINGv PF12906.7 CBZ36404.1 - 1.2e-11 44.6 5.4 1.2e-11 44.6 5.4 2.2 2 0 0 2 2 2 1 RING-variant domain BT1 PF03092.16 CBZ36405.1 - 0.00026 19.4 19.0 0.011 14.0 5.7 2.8 2 1 0 2 2 2 2 BT1 family ERGIC_N PF13850.6 CBZ36405.1 - 0.62 10.4 4.1 16 6.0 0.1 3.6 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF3311 PF11755.8 CBZ36405.1 - 1.7 8.7 8.0 5.2 7.1 0.2 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) Pro_isomerase PF00160.21 CBZ36406.1 - 7.8e-45 153.0 0.0 9.7e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ResIII PF04851.15 CBZ36408.1 - 7.1e-16 58.7 0.0 1.9e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ36408.1 - 3.5e-09 37.0 0.0 9.8e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T5orf172 PF10544.9 CBZ36408.1 - 1.3e-08 35.3 0.0 3.4e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain DEAD PF00270.29 CBZ36408.1 - 1.7e-07 31.2 0.0 2.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CBZ36408.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Jas PF16135.5 CBZ36408.1 - 0.036 14.3 0.1 0.13 12.4 0.1 1.9 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling OrsD PF12013.8 CBZ36408.1 - 0.06 13.8 0.6 0.19 12.2 0.6 1.9 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D FGase PF05013.12 CBZ36408.1 - 0.071 13.3 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase DUF3638 PF12340.8 CBZ36408.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) zf-CCCH_4 PF18044.1 CBZ36409.1 - 7.4e-06 25.6 12.8 0.00016 21.4 5.4 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ36409.1 - 2.4e-05 24.2 7.2 0.00035 20.5 1.0 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CBZ36409.1 - 3.8e-05 23.5 11.1 0.0009 19.1 3.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHH PF10283.9 CBZ36409.1 - 0.38 10.8 3.8 4.2 7.5 0.1 2.4 2 0 0 2 2 2 0 PBZ domain zf-CCCH_2 PF14608.6 CBZ36409.1 - 0.89 10.1 8.1 2.8 8.6 2.5 2.6 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CBZ36409.1 - 5.5 7.7 7.8 0.64 10.7 2.3 2.1 1 1 2 3 3 3 0 Torus domain Peptidase_C33 PF05412.12 CBZ36410.1 - 0.036 14.1 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase Peptidase_M22 PF00814.25 CBZ36411.1 - 8.2e-85 284.8 0.0 9.8e-85 284.5 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 CBZ36411.1 - 0.079 12.6 0.0 1.7 8.3 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus VCBS PF13517.6 CBZ36412.1 - 5.7e-12 46.0 23.4 0.00012 22.5 4.8 7.1 7 1 1 8 8 8 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 CBZ36412.1 - 0.0012 18.9 22.5 0.63 10.2 3.6 5.7 6 0 0 6 6 6 4 FG-GAP repeat BBS1 PF14779.6 CBZ36412.1 - 0.017 14.6 0.0 1.2 8.5 0.0 2.9 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 1 BBS2_C PF14782.6 CBZ36412.1 - 0.081 11.7 0.2 5.6 5.6 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, C-terminal Itfg2 PF15907.5 CBZ36412.1 - 0.24 10.4 1.2 25 3.8 0.0 3.4 3 1 1 4 4 4 0 Integrin-alpha FG-GAP repeat-containing protein 2 ZapB PF06005.12 CBZ36414.1 - 0.027 14.9 1.1 0.027 14.9 1.1 7.8 3 2 0 4 4 4 0 Cell division protein ZapB UCH PF00443.29 CBZ36415.1 - 1.5e-41 142.6 0.0 2.2e-41 142.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ36415.1 - 1.2e-11 44.8 0.0 1.2e-10 41.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CBZ36415.1 - 1.7e-08 34.1 0.1 4.4e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 CBZ36415.1 - 0.041 14.3 0.1 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain Peptidase_C98 PF15499.6 CBZ36415.1 - 0.048 13.1 0.1 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Polyoma_coat2 PF00761.20 CBZ36415.1 - 0.22 11.2 1.9 0.35 10.5 1.9 1.3 1 0 0 1 1 1 0 Polyomavirus coat protein RNA_pol_Rpb2_6 PF00562.28 CBZ36417.1 - 1.3e-120 403.1 0.0 1.7e-120 402.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CBZ36417.1 - 2.5e-42 144.7 0.0 3.7e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 CBZ36417.1 - 2.6e-31 107.9 0.1 1.1e-30 105.8 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 CBZ36417.1 - 6.8e-24 84.5 0.0 1.2e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 CBZ36417.1 - 7.5e-22 77.4 1.1 1.6e-21 76.3 1.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CBZ36417.1 - 2.5e-21 75.6 0.1 7.3e-21 74.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CBZ36417.1 - 7.7e-09 36.0 0.7 2e-08 34.7 0.7 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 OrfB_Zn_ribbon PF07282.11 CBZ36417.1 - 0.33 10.9 2.8 0.32 10.9 0.9 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF3176 PF11374.8 CBZ36418.1 - 0.0044 17.2 1.4 0.0077 16.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) 7TMR-DISM_7TM PF07695.11 CBZ36418.1 - 0.49 10.2 9.3 1.6 8.6 2.8 2.3 2 0 0 2 2 2 0 7TM diverse intracellular signalling Methyltr_RsmB-F PF01189.17 CBZ36420.1 - 1.3e-69 233.9 0.0 2.8e-69 232.8 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CBZ36420.1 - 3e-08 34.0 0.0 1.5e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CBZ36420.1 - 2.5e-05 24.5 0.1 7.9e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.19 CBZ36420.1 - 0.033 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.16 CBZ36420.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein CorA PF01544.18 CBZ36420.1 - 0.49 9.7 3.0 1 8.6 3.0 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein WD40 PF00400.32 CBZ36421.1 - 6.7e-14 52.1 10.8 0.012 16.5 0.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 CBZ36421.1 - 2.7e-10 40.6 0.2 4.7e-10 39.8 0.2 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 CBZ36421.1 - 0.00032 20.9 0.2 2.1 8.7 0.0 4.4 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 CBZ36421.1 - 0.023 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller CLP1_P PF16575.5 CBZ36422.1 - 2.2e-10 40.7 0.0 1e-09 38.5 0.0 2.0 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CBZ36422.1 - 2.3e-09 37.4 0.0 4.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CBZ36422.1 - 8.8e-05 22.9 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 SDA1 PF05285.12 CBZ36423.1 - 0.0073 15.8 16.9 0.0084 15.6 16.9 1.2 1 0 0 1 1 1 1 SDA1 DUF4746 PF15928.5 CBZ36423.1 - 0.092 12.2 10.3 0.12 11.8 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 CBZ36423.1 - 0.15 10.2 17.8 0.17 10.1 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family Nop16 PF09420.10 CBZ36423.1 - 0.35 10.9 5.6 0.44 10.5 5.6 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 TFIIF_alpha PF05793.12 CBZ36423.1 - 0.75 8.3 16.3 0.82 8.2 16.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 CBZ36423.1 - 2.2 6.5 13.1 2.7 6.2 13.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Cupin_4 PF08007.12 CBZ36425.1 - 7e-40 137.4 0.0 1.6e-38 133.0 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein Cupin_8 PF13621.6 CBZ36425.1 - 1.1e-06 28.5 0.0 1.7e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 CBZ36425.1 - 0.026 14.2 0.0 0.093 12.5 0.0 1.9 1 0 0 1 1 1 0 Cupin domain Cupin_3 PF05899.12 CBZ36425.1 - 0.17 11.6 0.0 0.53 10.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Helicase_C PF00271.31 CBZ36426.1 - 1.8e-10 41.1 0.0 4.5e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ36426.1 - 3.8e-06 26.8 0.0 8.9e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase 2OG-FeII_Oxy_3 PF13640.6 CBZ36429.1 - 7.2e-16 58.9 0.0 1.4e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 CBZ36429.1 - 3.6e-10 40.4 0.0 7.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily COPIIcoated_ERV PF07970.12 CBZ36430.1 - 1.6e-19 70.7 0.0 2.9e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBZ36430.1 - 3.5e-08 33.7 0.0 6.9e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Kinesin PF00225.23 CBZ36431.1 - 6.9e-90 301.3 1.0 2.3e-89 299.6 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ36431.1 - 4.5e-16 59.1 0.0 8.4e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding XLF PF09302.11 CBZ36431.1 - 0.17 12.1 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TMF_DNA_bd PF12329.8 CBZ36431.1 - 2.3 8.3 7.6 0.16 12.0 1.4 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CRAL_TRIO PF00650.20 CBZ36432.1 - 1.9e-12 47.2 0.0 3.7e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO PF00650.20 CBZ36433.1 - 1.1e-14 54.4 0.0 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Trp_Tyr_perm PF03222.13 CBZ36434.1 - 6.2e-07 28.8 7.6 8.1e-07 28.4 7.6 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 CBZ36434.1 - 1.8e-06 27.0 7.1 2.6e-06 26.4 7.1 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2207 PF09972.9 CBZ36434.1 - 0.0011 17.9 0.0 0.0013 17.6 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SdpI PF13630.6 CBZ36434.1 - 0.034 14.3 1.5 0.063 13.4 1.5 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF997 PF06196.12 CBZ36434.1 - 0.054 13.5 1.7 0.087 12.8 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) YhzD PF14120.6 CBZ36434.1 - 0.14 12.3 0.3 0.28 11.3 0.3 1.5 1 0 0 1 1 1 0 YhzD-like protein Orf78 PF06024.12 CBZ36434.1 - 6.2 7.2 5.1 3 8.2 1.9 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Trp_Tyr_perm PF03222.13 CBZ36435.1 - 7e-07 28.6 7.3 9.1e-07 28.3 7.3 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 CBZ36435.1 - 2e-06 26.8 6.9 2.9e-06 26.3 6.9 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2207 PF09972.9 CBZ36435.1 - 0.0011 17.9 0.0 0.0013 17.6 0.0 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SdpI PF13630.6 CBZ36435.1 - 0.034 14.3 1.5 0.063 13.4 1.5 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF997 PF06196.12 CBZ36435.1 - 0.054 13.5 1.7 0.086 12.9 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) YhzD PF14120.6 CBZ36435.1 - 0.14 12.3 0.3 0.28 11.3 0.3 1.5 1 0 0 1 1 1 0 YhzD-like protein Orf78 PF06024.12 CBZ36435.1 - 6.1 7.2 5.1 3 8.2 1.9 2.0 2 0 0 2 2 2 0 Orf78 (ac78) Aa_trans PF01490.18 CBZ36436.1 - 4.4e-53 180.5 32.9 5.5e-53 180.2 32.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CBZ36437.1 - 4.4e-53 180.5 32.9 5.5e-53 180.2 32.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CBZ36438.1 - 0.00074 18.3 2.2 0.00085 18.1 2.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 CBZ36439.1 - 2.9e-50 171.2 38.2 3.4e-50 170.9 38.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CBZ36439.1 - 1e-09 37.8 22.6 1e-09 37.8 22.6 2.0 2 0 0 2 2 2 1 Amino acid permease Trp_Tyr_perm PF03222.13 CBZ36439.1 - 1e-05 24.8 17.4 1e-05 24.8 17.4 2.0 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family CRAL_TRIO PF00650.20 CBZ36440.1 - 4.1e-13 49.4 0.0 6.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Syd PF07348.12 CBZ36440.1 - 0.096 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Syd protein (SUKH-2) Ribosomal_L12_N PF16320.5 CBZ36440.1 - 0.37 10.5 5.1 0.16 11.7 1.8 2.2 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain Peptidase_C2 PF00648.21 CBZ36443.1 - 1.8e-46 158.6 0.0 2.4e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ36443.1 - 4.3e-26 91.3 0.1 7.9e-26 90.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CBZ36444.1 - 1.5e-29 103.0 0.0 2.7e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ36444.1 - 1.9e-15 57.1 0.0 4.7e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DUF1935 PF09149.10 CBZ36445.1 - 3e-16 59.7 0.0 5.3e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CBZ36445.1 - 3.9e-16 58.9 0.0 8.8e-16 57.8 0.0 1.6 1 1 0 1 1 1 1 Calpain family cysteine protease Peptidase_C2 PF00648.21 CBZ36446.1 - 3e-34 118.4 0.0 4.2e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ36446.1 - 1.5e-22 79.9 0.0 2.6e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DivIC PF04977.15 CBZ36446.1 - 0.078 12.8 0.5 0.15 11.9 0.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Peptidase_C2 PF00648.21 CBZ36447.1 - 3.6e-50 170.7 0.0 5.2e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ36447.1 - 4.7e-21 75.1 0.1 1.2e-20 73.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Peptidase_C2 PF00648.21 CBZ36449.1 - 1.3e-65 221.4 0.0 1.7e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DUF1935 PF09149.10 CBZ36449.1 - 5.5e-18 65.2 0.2 1.1e-17 64.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) Calpain_III PF01067.22 CBZ36449.1 - 0.054 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Calpain large subunit, domain III AAA_16 PF13191.6 CBZ36450.1 - 0.0022 18.4 0.1 0.006 17.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 CBZ36450.1 - 0.089 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sulfotransfer_4 PF17784.1 CBZ36451.1 - 2.7e-42 145.1 0.0 6.6e-42 143.8 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain cNMP_binding PF00027.29 CBZ36452.1 - 7.3e-27 93.3 0.9 1e-07 31.9 0.0 4.6 4 1 0 4 4 4 4 Cyclic nucleotide-binding domain DnaJ PF00226.31 CBZ36454.1 - 9.5e-23 80.1 0.5 1.7e-22 79.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ-X PF14308.6 CBZ36454.1 - 0.0039 16.7 0.5 0.007 15.8 0.5 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing Toprim_2 PF13155.6 CBZ36454.1 - 0.17 12.3 0.0 9.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Toprim-like TRM13 PF05206.14 CBZ36455.1 - 8.3e-39 133.7 0.0 5.4e-27 95.0 0.0 3.0 1 1 1 2 2 2 2 Methyltransferase TRM13 zf-U11-48K PF05253.12 CBZ36455.1 - 5.2e-10 39.0 1.6 1.1e-09 38.0 1.6 1.6 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 CBZ36455.1 - 2.1e-07 30.6 10.0 2.1e-07 30.6 10.0 2.3 3 0 0 3 3 3 1 CCCH zinc finger in TRM13 protein zf-ACC PF17848.1 CBZ36455.1 - 0.056 13.5 1.8 0.058 13.5 0.1 2.0 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Methyltransf_32 PF13679.6 CBZ36455.1 - 0.58 10.1 5.3 8.3 6.4 5.3 2.5 1 1 0 1 1 1 0 Methyltransferase domain ABC_membrane_2 PF06472.15 CBZ36457.1 - 5.8e-75 252.2 3.7 5.8e-75 252.2 3.7 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CBZ36457.1 - 1.3e-15 58.1 0.0 3.1e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Med3 PF11593.8 CBZ36457.1 - 0.069 12.3 0.2 0.14 11.3 0.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FAM76 PF16046.5 CBZ36458.1 - 0.12 11.7 14.4 0.29 10.4 1.3 3.3 3 0 0 3 3 3 0 FAM76 protein DNA_pol_P_Exo PF18049.1 CBZ36458.1 - 0.13 11.7 1.0 1.3 8.4 0.1 2.5 3 0 0 3 3 3 0 DNA polymerase nu pseudo-exo Filament PF00038.21 CBZ36458.1 - 7.2 6.1 43.6 0.012 15.2 7.2 4.9 5 0 0 5 5 5 0 Intermediate filament protein GHMP_kinases_C PF08544.13 CBZ36459.1 - 6.6e-17 61.7 0.2 1.3e-16 60.8 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CBZ36459.1 - 3.8e-12 46.3 1.3 9.5e-12 45.0 1.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain YcaO PF02624.16 CBZ36459.1 - 0.033 13.5 0.0 0.097 11.9 0.0 1.7 2 1 0 2 2 2 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Dict-STAT-coil PF09267.10 CBZ36459.1 - 0.057 13.8 0.5 0.057 13.8 0.5 1.8 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil Hexokinase_2 PF03727.16 CBZ36459.1 - 0.091 12.2 0.3 2.3 7.6 0.0 2.1 1 1 1 2 2 2 0 Hexokinase Aa_trans PF01490.18 CBZ36460.1 - 2.2e-46 158.4 35.9 2.7e-46 158.1 35.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ36460.1 - 5.9e-12 45.3 13.8 5.9e-12 45.3 13.8 2.1 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Aa_trans PF01490.18 CBZ36461.1 - 5.5e-48 163.7 33.9 7.3e-48 163.3 33.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ36461.1 - 1.7e-07 30.7 14.0 1.7e-07 30.7 14.0 2.2 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family MaAIMP_sms PF16951.5 CBZ36461.1 - 0.098 12.4 0.3 0.098 12.4 0.3 2.4 2 0 0 2 2 2 0 Putative methionine and alanine importer, small subunit OppC_N PF12911.7 CBZ36461.1 - 2.4 8.2 5.4 10 6.2 0.3 3.5 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Aa_trans PF01490.18 CBZ36462.1 - 1e-41 143.0 33.5 1.4e-41 142.6 33.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FA_hydroxylase PF04116.13 CBZ36463.1 - 5.4e-16 59.1 13.7 1.1e-15 58.1 13.7 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily SPC12 PF06645.13 CBZ36464.1 - 0.02 15.0 0.3 0.044 13.9 0.3 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF5313 PF17240.2 CBZ36464.1 - 0.1 13.0 0.7 0.22 11.9 0.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Ribosomal_L7Ae PF01248.26 CBZ36465.1 - 0.0001 22.0 0.1 0.00026 20.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Antimicrobial19 PF08225.11 CBZ36465.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide DUF3391 PF11871.8 CBZ36465.1 - 0.05 14.1 0.1 0.17 12.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Tudor_1_RapA PF18339.1 CBZ36466.1 - 0.3 11.0 1.5 0.49 10.4 0.2 2.0 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain 1 FtsJ PF01728.19 CBZ36469.1 - 2.8e-43 148.1 0.0 3.5e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cecropin PF00272.19 CBZ36471.1 - 0.12 12.1 0.1 0.34 10.6 0.1 1.7 1 0 0 1 1 1 0 Cecropin family C2 PF00168.30 CBZ36472.1 - 1.2e-22 80.2 0.0 1.7e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain cPLA2_C2 PF18695.1 CBZ36472.1 - 0.0096 15.9 0.0 0.027 14.5 0.0 1.7 2 0 0 2 2 2 1 Cytosolic phospholipases A2 C2-domain DOCK-C2 PF14429.6 CBZ36472.1 - 0.012 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins Peptidase_M41 PF01434.18 CBZ36474.1 - 3.5e-45 154.2 0.0 1.1e-44 152.6 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CBZ36474.1 - 6.7e-34 117.2 0.0 1.4e-33 116.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ36474.1 - 6e-10 38.8 0.1 1.5e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CBZ36474.1 - 0.0012 19.1 0.5 0.6 10.4 0.1 2.9 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ36474.1 - 0.0015 18.5 0.8 0.17 11.9 0.3 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CBZ36474.1 - 0.0025 17.9 0.0 0.0068 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CBZ36474.1 - 0.0047 17.5 0.0 0.028 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ36474.1 - 0.012 16.0 1.1 0.055 13.9 1.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 CBZ36474.1 - 0.031 14.0 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CBZ36474.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 CBZ36474.1 - 0.087 13.1 0.2 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ36474.1 - 0.091 12.9 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CBZ36474.1 - 0.12 11.8 0.3 0.24 10.8 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MFS_1 PF07690.16 CBZ36476.1 - 1e-08 34.5 25.6 1e-08 34.5 25.6 3.8 2 2 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ36476.1 - 0.32 10.4 17.7 0.018 14.6 7.9 2.4 2 0 0 2 2 2 0 Nodulin-like CesT PF05932.13 CBZ36478.1 - 6.5e-18 65.0 0.3 7.8e-17 61.5 0.0 2.3 2 0 0 2 2 2 1 Tir chaperone protein (CesT) family DivIC PF04977.15 CBZ36478.1 - 0.0041 16.9 1.7 0.0074 16.0 1.7 1.4 1 0 0 1 1 1 1 Septum formation initiator DUF3450 PF11932.8 CBZ36478.1 - 0.0087 15.4 0.7 0.012 14.9 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) ZapB PF06005.12 CBZ36478.1 - 0.012 16.1 0.6 0.024 15.0 0.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 CBZ36478.1 - 0.012 16.1 1.5 0.019 15.5 1.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4200 PF13863.6 CBZ36478.1 - 0.019 15.4 2.0 0.034 14.6 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DHR10 PF18595.1 CBZ36478.1 - 0.021 14.9 5.5 0.038 14.1 5.5 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain MYO10_CC PF16735.5 CBZ36478.1 - 0.023 14.8 1.7 0.062 13.4 1.7 1.7 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain ADIP PF11559.8 CBZ36478.1 - 0.044 13.9 1.1 0.093 12.8 1.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 CBZ36478.1 - 0.053 13.8 2.4 0.11 12.8 2.4 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Phage_min_cap2 PF06152.11 CBZ36478.1 - 0.06 12.2 2.4 0.084 11.8 2.4 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 DUF1192 PF06698.11 CBZ36478.1 - 0.067 13.2 2.0 12 6.0 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Spc24 PF08286.11 CBZ36478.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.5 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF2543 PF10820.8 CBZ36479.1 - 0.015 15.5 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) Rab_bind PF16704.5 CBZ36479.1 - 0.061 13.4 1.1 0.17 11.9 1.1 1.8 1 0 0 1 1 1 0 Rab binding domain DUF16 PF01519.16 CBZ36479.1 - 0.28 11.7 2.3 1.1 9.8 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 SCP-1 PF05483.12 CBZ36480.1 - 0.0018 16.4 2.0 0.0022 16.1 2.0 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) Seryl_tRNA_N PF02403.22 CBZ36480.1 - 0.072 13.3 5.1 0.056 13.7 2.9 1.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain COG5 PF10392.9 CBZ36480.1 - 0.11 12.7 9.0 0.14 12.4 4.0 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Cucumopine_C PF18631.1 CBZ36480.1 - 0.13 12.2 0.5 7.2 6.6 0.0 2.9 1 1 2 3 3 3 0 Cucumopine synthase C-terminal helical bundle domain HJURP_C PF12347.8 CBZ36480.1 - 0.28 11.3 3.5 13 5.9 0.0 3.2 3 1 0 4 4 4 0 Holliday junction regulator protein family C-terminal repeat DUF16 PF01519.16 CBZ36480.1 - 0.95 10.0 7.0 1.9 9.0 4.3 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 UPF0242 PF06785.11 CBZ36480.1 - 1.2 9.2 8.9 0.54 10.3 5.6 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus KxDL PF10241.9 CBZ36480.1 - 2.5 8.4 12.4 6.1 7.2 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein HAUS6_N PF14661.6 CBZ36480.1 - 2.8 7.5 10.8 1.3 8.5 8.5 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus SlyX PF04102.12 CBZ36480.1 - 3 8.5 6.2 0.57 10.8 0.4 2.5 3 0 0 3 3 2 0 SlyX LMBR1 PF04791.16 CBZ36480.1 - 9.6 5.0 6.5 13 4.5 6.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PGBA_C PF15437.6 CBZ36481.1 - 0.00091 19.5 4.2 0.0024 18.2 4.2 1.7 1 0 0 1 1 1 1 Plasminogen-binding protein pgbA C-terminal LPD34 PF18852.1 CBZ36481.1 - 0.031 13.9 0.8 0.053 13.1 0.8 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 34 Rap1a PF18602.1 CBZ36481.1 - 0.06 13.7 0.2 0.25 11.7 0.1 2.1 2 0 0 2 2 2 0 Rap1a immunity proteins HsbA PF12296.8 CBZ36481.1 - 0.084 13.3 0.6 10 6.6 0.2 2.9 3 1 0 3 3 3 0 Hydrophobic surface binding protein A Fib_alpha PF08702.10 CBZ36481.1 - 0.26 11.5 4.8 0.089 13.0 1.7 1.8 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CotJB PF12652.7 CBZ36481.1 - 0.3 11.3 1.9 12 6.2 0.5 3.3 2 2 1 3 3 3 0 CotJB protein MamL-1 PF09596.10 CBZ36481.1 - 0.53 10.6 4.8 16 5.8 0.0 3.3 3 0 0 3 3 3 0 MamL-1 domain PhaP_Bmeg PF09602.10 CBZ36481.1 - 0.83 9.6 6.8 9.1 6.2 6.2 2.5 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) KapB PF08810.10 CBZ36481.1 - 1.6 8.9 6.6 0.94 9.7 0.2 2.9 2 1 0 2 2 2 0 Kinase associated protein B PRKG1_interact PF15898.5 CBZ36481.1 - 2 9.3 8.0 0.78 10.7 4.4 2.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain C2 PF00168.30 CBZ36482.1 - 4.5e-19 68.6 0.0 8.2e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 C2 domain DOCK-C2 PF14429.6 CBZ36482.1 - 0.11 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins C2 PF00168.30 CBZ36483.1 - 8.6e-22 77.4 0.1 1.2e-21 77.0 0.1 1.2 1 0 0 1 1 1 1 C2 domain DOCK-C2 PF14429.6 CBZ36483.1 - 0.017 14.9 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 C2 domain in Dock180 and Zizimin proteins FAD-SLDH PF12318.8 CBZ36485.1 - 0.065 13.3 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Lipase_3 PF01764.25 CBZ36487.1 - 2.3e-29 102.1 0.0 4e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CBZ36487.1 - 0.00014 21.2 0.1 0.0002 20.7 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CBZ36487.1 - 0.00054 20.6 0.8 0.0008 20.1 0.8 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 CBZ36487.1 - 0.066 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF2974 PF11187.8 CBZ36487.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF5512 PF17631.2 CBZ36487.1 - 0.15 12.1 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5512) Lipase_3 PF01764.25 CBZ36488.1 - 4.1e-38 130.4 0.0 5.2e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 CBZ36488.1 - 0.0028 17.3 0.1 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CBZ36488.1 - 0.0035 18.0 0.1 0.0044 17.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBZ36488.1 - 0.0081 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 CBZ36488.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 CBZ36488.1 - 0.07 12.8 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 CBZ36488.1 - 0.079 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 CBZ36488.1 - 0.081 12.7 0.0 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family PhdYeFM_antitox PF02604.19 CBZ36488.1 - 0.13 12.0 0.0 0.4 10.5 0.0 1.7 2 0 0 2 2 2 0 Antitoxin Phd_YefM, type II toxin-antitoxin system DUF676 PF05057.14 CBZ36488.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2048 PF09752.9 CBZ36488.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 HsbA PF12296.8 CBZ36489.1 - 0.0028 18.1 0.3 2.5 8.6 0.1 3.0 3 1 0 3 3 3 2 Hydrophobic surface binding protein A PGBA_C PF15437.6 CBZ36489.1 - 0.0036 17.6 5.6 0.0087 16.4 5.6 1.6 1 0 0 1 1 1 1 Plasminogen-binding protein pgbA C-terminal Fib_alpha PF08702.10 CBZ36489.1 - 0.038 14.2 2.0 0.1 12.8 1.0 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family BAR_3 PF16746.5 CBZ36489.1 - 0.1 12.3 12.1 1.3 8.6 7.5 2.1 1 1 1 2 2 2 0 BAR domain of APPL family PhaP_Bmeg PF09602.10 CBZ36489.1 - 0.19 11.7 7.0 2.2 8.2 6.2 2.6 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) MCPsignal PF00015.21 CBZ36489.1 - 0.21 11.4 1.8 1.2 8.9 0.0 2.7 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain KapB PF08810.10 CBZ36489.1 - 0.26 11.5 0.2 0.26 11.5 0.2 3.1 2 1 0 2 2 2 0 Kinase associated protein B CotJB PF12652.7 CBZ36489.1 - 0.45 10.8 1.9 13 6.0 0.6 3.2 2 2 1 3 3 3 0 CotJB protein MamL-1 PF09596.10 CBZ36489.1 - 1.4 9.3 5.5 18 5.7 0.0 3.1 3 0 0 3 3 3 0 MamL-1 domain RSS_P20 PF11757.8 CBZ36489.1 - 7.8 7.0 7.3 4.7 7.7 3.1 2.7 2 2 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Ras PF00071.22 CBZ36490.1 - 4.5e-23 81.6 0.9 5.4e-19 68.4 0.0 2.6 2 1 0 2 2 2 2 Ras family Roc PF08477.13 CBZ36490.1 - 1.3e-15 57.6 0.0 1.9e-09 37.8 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ36490.1 - 2.2e-07 30.5 0.0 1.9e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBZ36490.1 - 4.2e-07 29.7 0.1 7.7e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ36490.1 - 0.0001 22.4 0.0 0.00036 20.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBZ36490.1 - 0.00062 19.2 0.1 0.0023 17.3 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 CBZ36490.1 - 0.033 13.0 0.0 9.2 5.0 0.0 2.6 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) RsgA_GTPase PF03193.16 CBZ36490.1 - 0.11 12.4 0.1 19 5.1 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase Aa_trans PF01490.18 CBZ36493.1 - 5.6e-47 160.3 42.1 6.8e-47 160.1 42.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ36493.1 - 3.7e-05 22.9 31.2 7.6e-05 21.9 31.2 1.6 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family OST3_OST6 PF04756.13 CBZ36493.1 - 2.4 7.5 11.6 0.18 11.1 5.4 2.2 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family KIAA1430 PF13879.6 CBZ36494.1 - 9.2e-18 64.9 1.6 1.7e-17 64.1 1.6 1.4 1 0 0 1 1 1 1 KIAA1430 homologue DUF3852 PF12963.7 CBZ36495.1 - 0.052 13.9 0.5 0.12 12.7 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3852) DUF2244 PF10003.9 CBZ36495.1 - 0.059 13.0 0.5 0.072 12.8 0.5 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Bax1-I PF01027.20 CBZ36495.1 - 0.094 12.5 0.2 0.11 12.4 0.2 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2244 PF10003.9 CBZ36498.1 - 0.034 13.8 0.5 0.046 13.4 0.5 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Bax1-I PF01027.20 CBZ36498.1 - 0.042 13.7 0.5 0.046 13.5 0.5 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF3852 PF12963.7 CBZ36498.1 - 0.049 14.0 1.1 0.14 12.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3852) HTH_Tnp_1 PF01527.20 CBZ36499.1 - 0.026 14.8 0.3 1.3 9.4 0.0 3.1 3 0 0 3 3 3 0 Transposase X PF00739.19 CBZ36499.1 - 0.52 10.4 3.4 2.9 8.0 3.4 2.3 1 0 0 1 1 1 0 Trans-activation protein X RBR PF17208.3 CBZ36501.1 - 0.1 13.3 4.3 0.06 14.1 1.1 2.5 2 0 0 2 2 2 0 RNA binding Region RBR PF17208.3 CBZ36502.1 - 0.02 15.6 0.1 0.02 15.6 0.1 4.5 3 1 1 5 5 5 0 RNA binding Region DUF4217 PF13959.6 CBZ36504.1 - 0.0077 16.4 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) RRM_1 PF00076.22 CBZ36506.1 - 9.7e-06 25.3 0.0 1.8e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YhfH PF14149.6 CBZ36506.1 - 0.029 14.3 1.4 0.28 11.2 0.1 2.5 2 0 0 2 2 2 0 YhfH-like protein RRM_1 PF00076.22 CBZ36507.1 - 7e-08 32.2 0.0 1.3e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 CBZ36509.1 - 4.1e-08 33.8 0.0 3.7e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 SET domain BPL_LplA_LipB PF03099.19 CBZ36510.1 - 1.7e-11 44.2 0.0 3.2e-11 43.2 0.0 1.5 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Nup54 PF13874.6 CBZ36511.1 - 0.004 17.3 1.2 0.004 17.3 1.2 1.8 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Gp58 PF07902.11 CBZ36511.1 - 0.059 11.7 2.0 0.083 11.2 2.0 1.1 1 0 0 1 1 1 0 gp58-like protein Apolipoprotein PF01442.18 CBZ36511.1 - 0.2 11.5 9.6 1 9.2 9.3 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain SlyX PF04102.12 CBZ36511.1 - 1.1 9.9 3.2 68 4.2 0.0 2.7 2 0 0 2 2 2 0 SlyX OmpH PF03938.14 CBZ36511.1 - 1.6 9.1 10.3 0.22 11.9 0.4 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 CBZ36511.1 - 1.9 7.7 2.8 2.8 7.1 2.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein DHR10 PF18595.1 CBZ36511.1 - 6.6 6.8 12.7 1.9 8.6 7.8 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain DUF4498 PF14926.6 CBZ36513.1 - 3.9e-18 65.7 0.0 1.2e-11 44.5 0.0 3.9 3 1 0 3 3 3 2 Domain of unknown function (DUF4498) EMP24_GP25L PF01105.24 CBZ36514.1 - 3.3e-28 98.9 0.0 3.9e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Gypsy PF07253.11 CBZ36514.1 - 0.001 17.7 0.7 0.0015 17.2 0.7 1.1 1 0 0 1 1 1 1 Gypsy protein PBECR5 PF18814.1 CBZ36514.1 - 0.12 12.3 0.2 0.18 11.7 0.2 1.1 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 EMP24_GP25L PF01105.24 CBZ36515.1 - 1.4e-19 70.8 0.0 1.6e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Peptidase_M20 PF01546.28 CBZ36516.1 - 1e-26 93.9 0.1 1.3e-26 93.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ36516.1 - 4.7e-10 39.3 0.0 8.9e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Hydrolase_4 PF12146.8 CBZ36517.1 - 7.6e-65 218.5 0.0 1e-64 218.1 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ36517.1 - 3.7e-15 56.3 0.0 3.7e-12 46.4 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBZ36517.1 - 3.5e-13 50.7 0.0 4.8e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBZ36517.1 - 2.1e-10 40.5 0.1 6.9e-09 35.5 0.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 CBZ36517.1 - 0.00037 20.1 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 CBZ36517.1 - 0.00055 19.6 0.0 0.06 12.9 0.1 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF2920 PF11144.8 CBZ36517.1 - 0.001 18.4 0.1 0.82 8.8 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.13 CBZ36517.1 - 0.0062 16.4 0.0 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 CBZ36517.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 CBZ36517.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Palm_thioest PF02089.15 CBZ36517.1 - 0.013 15.4 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 CBZ36517.1 - 0.014 15.3 0.0 1 9.2 0.0 2.2 1 1 0 2 2 2 0 Serine hydrolase Abhydrolase_2 PF02230.16 CBZ36517.1 - 0.019 14.7 0.1 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 CBZ36517.1 - 0.026 14.6 0.1 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain AXE1 PF05448.12 CBZ36517.1 - 0.034 12.8 0.6 1.3 7.6 0.0 2.4 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 CBZ36517.1 - 0.035 13.8 0.0 0.092 12.4 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_8 PF06259.12 CBZ36517.1 - 0.06 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_5 PF12695.7 CBZ36517.1 - 0.067 12.9 0.0 0.53 10.0 0.0 2.2 3 0 0 3 3 3 0 Alpha/beta hydrolase family LRR_4 PF12799.7 CBZ36519.1 - 5.7e-10 39.3 12.4 0.15 12.5 0.2 7.1 5 1 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ36519.1 - 3.3e-06 26.8 3.9 0.38 10.5 0.8 4.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 CBZ36519.1 - 0.0019 17.7 1.3 0.14 11.7 0.2 3.0 2 1 1 3 3 3 1 Leucine-rich repeat DUF5538 PF17692.1 CBZ36519.1 - 0.072 13.2 1.7 0.16 12.1 0.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5538) DUF4372 PF14294.6 CBZ36519.1 - 0.97 9.6 3.6 30 4.8 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4372) Cyt-b5 PF00173.28 CBZ36520.1 - 3.3e-06 27.1 0.0 5.5e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 CBZ36521.1 - 9e-08 32.2 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4335 PF14233.6 CBZ36521.1 - 0.029 14.3 0.4 0.047 13.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Cyt-b5 PF00173.28 CBZ36522.1 - 3.3e-05 23.9 0.0 4.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 CBZ36523.1 - 9.9e-09 35.2 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 CBZ36524.1 - 6.1e-09 35.9 0.0 9.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3638 PF12340.8 CBZ36525.1 - 1.2e-29 103.2 0.1 1e-28 100.2 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 CBZ36525.1 - 7.4e-16 57.2 0.5 2.7e-15 55.4 0.5 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) zf-RanBP PF00641.18 CBZ36525.1 - 1.8e-08 33.6 20.7 2e-05 23.8 4.3 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Thioredoxin_8 PF13905.6 CBZ36525.1 - 2.7e-06 27.6 0.0 6.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like ubiquitin PF00240.23 CBZ36525.1 - 0.00072 19.3 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Vps36-NZF-N PF16988.5 CBZ36525.1 - 3.3 7.2 13.3 1.5 8.2 2.3 3.6 2 1 1 3 3 3 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain H_PPase PF03030.16 CBZ36526.1 - 5.1e-239 795.3 33.4 6.7e-239 794.9 33.4 1.2 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase RP853 PF17542.2 CBZ36526.1 - 3.9 6.5 5.6 1.4 7.9 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized RP853 LRR_6 PF13516.6 CBZ36527.1 - 0.00053 19.8 3.6 3.7 7.8 0.0 4.7 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 CBZ36527.1 - 0.1 13.2 4.7 4.2 8.3 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat GvpG PF05120.12 CBZ36527.1 - 0.12 12.4 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 Gas vesicle protein G LRR_4 PF12799.7 CBZ36527.1 - 1.1 9.8 7.4 2.8 8.5 0.3 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Spt20 PF12090.8 CBZ36528.1 - 0.0037 16.9 2.3 0.0037 16.9 2.3 2.3 2 0 0 2 2 2 1 Spt20 family MT PF12777.7 CBZ36530.1 - 9.6e-07 28.1 6.4 1.7e-06 27.3 0.2 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Borrelia_REV PF03978.13 CBZ36530.1 - 0.0033 17.4 1.3 0.011 15.8 1.3 1.9 1 0 0 1 1 1 1 Borrelia burgdorferi REV protein DUF5082 PF16888.5 CBZ36530.1 - 0.48 10.7 0.1 0.48 10.7 0.1 4.3 4 2 1 5 5 5 0 Domain of unknown function (DUF5082) Bacillus_HBL PF05791.11 CBZ36530.1 - 0.93 9.3 9.1 1.3 8.8 0.1 3.1 4 0 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Nas2_N PF18265.1 CBZ36530.1 - 3.1 7.8 6.4 0.95 9.4 0.7 3.0 3 0 0 3 3 3 0 Nas2 N_terminal domain ABC_membrane PF00664.23 CBZ36531.1 - 1.7e-53 182.0 32.7 7.8e-31 107.7 14.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ36531.1 - 1.3e-35 122.9 0.0 1.6e-20 74.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 CBZ36531.1 - 2.3e-10 40.0 2.0 1.2e-05 25.0 0.1 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CBZ36531.1 - 5.5e-09 36.3 0.0 0.003 17.4 0.0 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ36531.1 - 1.1e-07 32.6 0.0 0.00017 22.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ36531.1 - 7e-07 29.8 2.9 0.004 17.6 0.0 3.7 3 0 0 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 CBZ36531.1 - 1.6e-06 27.4 0.0 0.01 14.9 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.19 CBZ36531.1 - 6.9e-06 25.6 0.1 0.044 13.2 0.0 3.3 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 CBZ36531.1 - 1.1e-05 25.0 0.2 0.016 14.5 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CBZ36531.1 - 2e-05 24.6 0.3 0.22 11.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ36531.1 - 6.4e-05 22.9 0.2 0.0071 16.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CBZ36531.1 - 7e-05 23.0 0.3 0.015 15.3 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 CBZ36531.1 - 7.7e-05 22.5 2.1 0.27 10.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CBZ36531.1 - 0.00015 21.4 0.4 0.024 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBZ36531.1 - 0.00024 21.4 0.6 0.24 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CBZ36531.1 - 0.00032 19.8 0.3 0.34 9.8 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 CBZ36531.1 - 0.00032 20.9 0.8 0.59 10.2 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 CBZ36531.1 - 0.00074 19.5 1.5 0.13 12.2 0.0 3.1 3 0 0 3 3 3 1 NACHT domain ATP_bind_1 PF03029.17 CBZ36531.1 - 0.022 14.5 0.7 5.3 6.8 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 CBZ36531.1 - 0.024 13.6 0.6 0.69 8.8 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 CBZ36531.1 - 0.028 14.0 3.4 0.86 9.2 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CBZ36531.1 - 0.036 13.8 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CBZ36531.1 - 0.04 13.4 0.1 8.5 5.8 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 CBZ36531.1 - 0.042 13.6 0.1 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 CBZ36531.1 - 0.045 13.9 1.9 0.85 9.8 0.2 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBZ36531.1 - 0.056 13.8 0.1 2.5 8.5 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_18 PF13238.6 CBZ36531.1 - 0.1 13.1 0.1 6 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 CBZ36531.1 - 0.12 11.1 0.6 0.52 9.1 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein IstB_IS21 PF01695.17 CBZ36531.1 - 0.15 11.8 0.1 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein CAP_GLY PF01302.25 CBZ36531.1 - 0.19 11.8 0.6 0.44 10.6 0.4 1.7 2 0 0 2 2 1 0 CAP-Gly domain AAA_5 PF07728.14 CBZ36531.1 - 0.2 11.7 0.3 10 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.14 CBZ36531.1 - 0.24 11.3 0.2 18 5.3 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 CBZ36531.1 - 0.28 11.1 0.1 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_15 PF13175.6 CBZ36531.1 - 0.32 10.7 0.0 5.5 6.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CBZ36531.1 - 0.6 10.3 1.7 30 4.8 0.2 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase E1-E2_ATPase PF00122.20 CBZ36531.1 - 2.3 7.7 5.5 1.3 8.5 1.6 2.4 2 0 0 2 2 2 0 E1-E2 ATPase ABC_membrane PF00664.23 CBZ36532.1 - 3.6e-18 66.2 3.7 5.5e-18 65.6 3.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region CAP_GLY PF01302.25 CBZ36532.1 - 0.074 13.1 1.0 0.15 12.1 0.4 1.8 2 0 0 2 2 2 0 CAP-Gly domain CAP_GLY PF01302.25 CBZ36533.1 - 0.014 15.4 0.7 0.056 13.5 0.4 2.0 2 0 0 2 2 2 0 CAP-Gly domain ALF PF03752.13 CBZ36534.1 - 1.9 8.5 5.2 4.6 7.3 2.0 2.9 2 0 0 2 2 2 0 Short repeats of unknown function DUF4150 PF13665.6 CBZ36535.1 - 0.05 13.8 2.4 3.4 7.8 0.2 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) PP2C PF00481.21 CBZ36536.1 - 1.2e-31 110.3 0.1 2.6e-27 96.1 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C zf-UBP PF02148.19 CBZ36536.1 - 0.074 13.4 10.3 0.18 12.2 10.3 1.7 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 CBZ36536.1 - 0.25 11.1 2.8 0.55 10.0 2.8 1.5 1 0 0 1 1 1 0 Variant UBP zinc finger CSD PF00313.22 CBZ36537.1 - 2.8e-07 30.3 0.0 0.0002 21.1 0.1 2.4 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain TEX13 PF15186.6 CBZ36537.1 - 0.38 10.4 3.5 0.67 9.6 3.5 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family CSD PF00313.22 CBZ36538.1 - 1.1e-10 41.2 0.0 2.3e-07 30.6 0.0 2.7 3 0 0 3 3 3 2 'Cold-shock' DNA-binding domain CSD PF00313.22 CBZ36539.1 - 0.00049 19.9 0.3 0.82 9.6 0.0 2.5 2 0 0 2 2 2 2 'Cold-shock' DNA-binding domain ParD_antitoxin PF03693.14 CBZ36540.1 - 0.038 14.4 1.0 0.11 12.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH DivIC PF04977.15 CBZ36540.1 - 0.18 11.6 0.2 0.18 11.6 0.2 5.1 4 2 1 5 5 5 0 Septum formation initiator Tmemb_cc2 PF10267.9 CBZ36540.1 - 5.2 6.1 15.4 0.4 9.8 1.9 2.6 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein SPRY PF00622.28 CBZ36541.1 - 1.4e-05 25.2 0.0 3.7e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 SPRY domain DUF1388 PF07142.12 CBZ36541.1 - 0.0021 18.0 0.3 0.011 15.7 0.3 2.3 1 0 0 1 1 1 1 Repeat of unknown function (DUF1388) Neuralized PF07177.12 CBZ36541.1 - 0.15 12.0 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 Neuralized DUF1366 PF07104.11 CBZ36542.1 - 0.83 9.4 7.4 0.17 11.5 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) zf-LSD1 PF06943.12 CBZ36544.1 - 2e-10 40.3 7.0 2e-10 40.3 7.0 2.4 2 0 0 2 2 2 1 LSD1 zinc finger zinc-ribbons_6 PF07191.12 CBZ36544.1 - 0.082 12.9 10.6 0.71 9.9 7.3 2.2 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 CBZ36544.1 - 0.11 12.5 15.2 7 6.8 11.0 2.3 1 1 1 2 2 2 0 Double zinc ribbon Tmemb_55A PF09788.9 CBZ36544.1 - 0.34 10.0 12.9 4 6.4 13.1 1.9 1 1 0 1 1 1 0 Transmembrane protein 55A zinc_ribbon_4 PF13717.6 CBZ36544.1 - 1 9.3 0.0 1 9.3 0.0 4.0 3 1 1 4 4 3 0 zinc-ribbon domain HypA PF01155.19 CBZ36544.1 - 7 6.7 11.6 2 8.4 0.8 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 CBZ36544.1 - 7.8 6.5 10.9 3.8 7.5 2.4 2.7 1 1 2 3 3 3 0 Putative transposase DNA-binding domain Glyco_trans_1_2 PF13524.6 CBZ36545.1 - 2.2 8.8 5.1 2 8.8 0.7 2.8 3 0 0 3 3 3 0 Glycosyl transferases group 1 RcsF PF16358.5 CBZ36546.1 - 0.015 15.4 0.8 0.12 12.5 0.1 2.5 2 0 0 2 2 2 0 RcsF lipoprotein ABC_tran PF00005.27 CBZ36548.1 - 2.9e-43 147.7 0.0 1e-24 87.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBZ36548.1 - 6.3e-39 134.3 16.5 3e-20 73.0 6.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CBZ36548.1 - 4.6e-09 36.0 0.2 0.051 13.0 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBZ36548.1 - 7.7e-08 32.5 0.0 0.013 15.3 0.0 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CBZ36548.1 - 1.3e-06 28.9 1.6 0.0073 16.7 0.1 3.3 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 CBZ36548.1 - 2.1e-06 27.4 0.0 0.099 12.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 CBZ36548.1 - 1.4e-05 24.3 0.0 0.072 12.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 CBZ36548.1 - 2.2e-05 23.9 0.1 0.025 13.9 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.6 CBZ36548.1 - 0.00027 21.2 1.8 0.23 11.7 0.1 3.0 3 0 0 3 3 2 2 AAA domain TrwB_AAD_bind PF10412.9 CBZ36548.1 - 0.0004 19.4 0.4 0.3 10.0 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 CBZ36548.1 - 0.00045 20.8 0.0 0.49 10.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CBZ36548.1 - 0.00047 20.2 0.1 0.38 10.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 CBZ36548.1 - 0.0017 18.1 0.3 1.8 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 CBZ36548.1 - 0.0073 15.3 1.1 1.6 7.6 0.2 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 CBZ36548.1 - 0.013 15.4 0.3 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase CAP_GLY PF01302.25 CBZ36548.1 - 0.02 14.9 0.0 0.061 13.4 0.0 1.8 1 0 0 1 1 1 0 CAP-Gly domain AAA_25 PF13481.6 CBZ36548.1 - 0.023 14.3 0.6 2.4 7.7 0.1 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CBZ36548.1 - 0.029 14.3 1.3 3 7.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 CBZ36548.1 - 0.042 13.9 5.9 0.65 10.1 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 CBZ36548.1 - 0.063 12.8 0.1 6 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CBZ36548.1 - 0.077 12.3 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 CBZ36548.1 - 0.11 12.4 0.1 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATP-synt_ab PF00006.25 CBZ36548.1 - 0.13 11.9 0.0 7.4 6.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 CBZ36548.1 - 0.14 11.8 0.0 1.4 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CBZ36548.1 - 0.21 11.2 3.6 5.2 6.6 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 CBZ36548.1 - 0.41 9.8 1.1 1.3 8.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.23 CBZ36548.1 - 0.67 10.0 2.8 21 5.1 0.2 2.3 2 0 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 CBZ36548.1 - 3.5 7.8 5.7 5.9 7.0 0.2 2.9 3 0 0 3 3 3 0 AAA domain LRRNT_2 PF08263.12 CBZ36549.1 - 0.0035 17.6 0.1 0.0067 16.7 0.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain DUF3982 PF13138.6 CBZ36549.1 - 0.086 12.6 0.1 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3982) Mucin PF01456.17 CBZ36550.1 - 8.7e-09 35.5 37.7 8.7e-09 35.5 37.7 2.2 2 0 0 2 2 2 1 Mucin-like glycoprotein LRR_8 PF13855.6 CBZ36550.1 - 4e-07 29.7 0.1 0.00068 19.3 0.0 2.9 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBZ36550.1 - 2.1e-05 24.8 0.0 0.027 14.9 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 CBZ36550.1 - 0.17 12.2 0.1 0.17 12.2 0.1 3.4 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain KAR9 PF08580.10 CBZ36550.1 - 1.6 7.2 4.6 1.8 7.0 4.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 LRR_8 PF13855.6 CBZ36551.1 - 8.6e-05 22.2 0.1 0.028 14.2 0.2 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CBZ36551.1 - 0.012 16.0 4.5 0.021 15.2 0.2 3.1 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 CBZ36553.1 - 2.7e-12 46.7 11.3 2.9 8.4 0.4 10.0 8 2 1 10 10 10 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ36553.1 - 2.5e-07 30.2 15.1 0.13 12.4 0.1 11.2 13 0 0 13 13 13 1 Leucine Rich repeat LRR_8 PF13855.6 CBZ36553.1 - 0.00035 20.3 13.0 0.24 11.2 0.1 7.5 7 1 1 8 8 8 1 Leucine rich repeat TTSSLRR PF12468.8 CBZ36553.1 - 0.038 14.2 0.1 0.097 12.9 0.1 1.6 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Pkinase PF00069.25 CBZ36558.1 - 8.6e-40 136.8 0.0 2.6e-27 95.9 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36558.1 - 1.6e-20 73.5 0.0 8.8e-10 38.3 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase PH_3 PF14593.6 CBZ36558.1 - 0.0017 18.4 0.0 0.029 14.5 0.0 2.3 2 0 0 2 2 2 1 PH domain APH PF01636.23 CBZ36558.1 - 0.075 12.9 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ36558.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like L51_S25_CI-B8 PF05047.16 CBZ36560.1 - 1.4e-10 40.9 0.0 2.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LysR_substrate PF03466.20 CBZ36560.1 - 0.1 11.9 0.2 0.51 9.7 0.0 1.9 2 0 0 2 2 2 0 LysR substrate binding domain TFCD_C PF12612.8 CBZ36561.1 - 0.1 12.5 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal Cmc1 PF08583.10 CBZ36563.1 - 0.037 14.0 3.8 0.097 12.7 3.8 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ribosomal_L36 PF00444.18 CBZ36564.1 - 0.0008 19.6 0.1 0.0016 18.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 LRR_4 PF12799.7 CBZ36565.1 - 8e-34 115.1 29.6 0.00031 21.1 2.3 12.6 9 1 3 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ36565.1 - 1.2e-11 44.1 35.4 2.6e-05 23.9 1.3 9.6 6 2 7 13 13 13 8 Leucine rich repeat LRR_6 PF13516.6 CBZ36565.1 - 1.3e-08 34.2 35.9 1.2 9.4 0.0 14.6 18 0 0 18 18 18 3 Leucine Rich repeat WAP PF00095.21 CBZ36565.1 - 0.045 14.1 1.1 0.045 14.1 1.1 2.2 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' LRR_2 PF07723.13 CBZ36565.1 - 0.047 14.4 0.6 28 5.6 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_1 PF00560.33 CBZ36565.1 - 8.4 7.4 17.3 48 5.1 0.0 8.6 10 1 0 10 10 10 0 Leucine Rich Repeat TP_methylase PF00590.20 CBZ36566.1 - 1.5e-20 74.0 0.1 2.7e-20 73.2 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NolV PF06635.12 CBZ36566.1 - 0.007 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein NolV DUF4434 PF14488.6 CBZ36566.1 - 0.036 14.1 0.0 0.071 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) NTPase_I-T PF01931.18 CBZ36567.1 - 2.4e-53 180.2 0.1 2.7e-53 180.1 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Flg_bb_rod PF00460.20 CBZ36567.1 - 0.054 13.4 0.2 0.091 12.7 0.2 1.4 1 0 0 1 1 1 0 Flagella basal body rod protein zf-MYND PF01753.18 CBZ36569.1 - 4.5e-10 39.4 9.3 4.5e-10 39.4 9.3 2.2 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 CBZ36569.1 - 0.00035 20.8 11.5 0.00093 19.5 11.5 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 CBZ36569.1 - 1.4 9.1 7.2 1.4 9.1 5.3 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Sld5 PF05916.11 CBZ36570.1 - 6.6e-09 36.2 0.0 8.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Filament PF00038.21 CBZ36572.1 - 0.0063 16.1 1.3 0.0099 15.5 1.2 1.4 1 1 0 1 1 1 1 Intermediate filament protein DUF1682 PF07946.14 CBZ36572.1 - 2 7.5 4.5 4.5 6.4 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) UME PF08064.13 CBZ36573.1 - 0.076 12.9 0.9 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 UME (NUC010) domain PPR_3 PF13812.6 CBZ36574.1 - 0.00099 19.1 0.7 1.1 9.3 0.0 2.9 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 CBZ36574.1 - 0.0013 18.9 0.2 21 5.4 0.0 4.5 4 0 0 4 4 4 1 PPR repeat family Cullin_Nedd8 PF10557.9 CBZ36576.1 - 1e-13 51.1 2.2 2.5e-13 49.8 2.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Cullin PF00888.22 CBZ36576.1 - 0.0021 16.8 0.1 0.035 12.7 0.1 2.3 1 1 0 1 1 1 1 Cullin family NAP PF00956.18 CBZ36579.1 - 3.9e-76 255.8 0.6 3.9e-76 255.8 0.6 1.6 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DNA_pol_phi PF04931.13 CBZ36579.1 - 0.037 12.1 6.9 0.066 11.3 6.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi Ni_hydr_CYTB PF01292.20 CBZ36581.1 - 0.089 12.4 0.6 3.6 7.2 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 TRAM_LAG1_CLN8 PF03798.16 CBZ36582.1 - 2.1e-40 138.6 12.6 2.1e-40 138.6 12.6 2.2 2 0 0 2 2 2 1 TLC domain Tachystatin_B PF11478.8 CBZ36582.1 - 2 8.5 6.1 0.26 11.3 1.0 2.2 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B M20_dimer PF07687.14 CBZ36585.1 - 1.1e-07 31.7 0.0 1.5e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain Aa_trans PF01490.18 CBZ36586.1 - 4.8e-22 78.2 6.7 5.7e-22 78.0 6.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ36586.1 - 7.6e-10 38.4 9.7 1e-09 37.9 9.7 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 CBZ36586.1 - 0.00014 20.9 13.8 0.00017 20.6 13.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1145 PF06611.12 CBZ36586.1 - 1.4 9.0 5.4 5.6 7.0 5.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1145) Aa_trans PF01490.18 CBZ36587.1 - 3.8e-07 29.2 0.4 3.8e-07 29.2 0.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CBZ36587.1 - 0.0014 17.6 1.7 0.0018 17.2 1.7 1.0 1 0 0 1 1 1 1 Amino acid permease SNF PF00209.18 CBZ36588.1 - 0.0065 15.2 0.6 0.0097 14.6 0.6 1.2 1 0 0 1 1 1 1 Sodium:neurotransmitter symporter family Orf78 PF06024.12 CBZ36592.1 - 0.046 14.0 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Glycos_transf_1 PF00534.20 CBZ36593.1 - 2.6e-15 56.4 0.0 1e-14 54.5 0.0 1.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ36593.1 - 1.8e-12 47.8 0.2 1.1e-11 45.3 0.1 2.3 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBZ36593.1 - 1.3e-05 25.5 0.0 3.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBZ36593.1 - 0.00099 19.1 1.6 0.002 18.2 0.3 2.2 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_transf_90 PF05686.12 CBZ36593.1 - 0.0078 15.2 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 90 ubiquitin PF00240.23 CBZ36594.1 - 2.1e-33 113.9 0.2 2.7e-33 113.5 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CBZ36594.1 - 1.1e-27 95.7 10.6 1.6e-27 95.1 10.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CBZ36594.1 - 5.7e-17 61.3 0.2 8e-17 60.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CBZ36594.1 - 2.4e-05 24.7 0.0 0.0001 22.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CBZ36594.1 - 0.0029 17.5 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBZ36594.1 - 0.0037 17.6 0.1 0.0076 16.6 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CBZ36594.1 - 0.0071 16.4 0.1 0.014 15.5 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CBZ36594.1 - 0.043 13.9 0.6 7.6 6.7 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain UPF0547 PF10571.9 CBZ36594.1 - 3.3 7.9 6.3 5.2 7.2 6.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 RINGv PF12906.7 CBZ36596.1 - 3.1e-12 46.4 6.5 8.4e-12 45.0 6.5 1.8 1 0 0 1 1 1 1 RING-variant domain Dus PF01207.17 CBZ36597.1 - 3.1e-50 171.0 0.6 3e-20 72.5 0.0 4.2 4 0 0 4 4 4 4 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 CBZ36597.1 - 0.052 12.7 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Thioredoxin_8 PF13905.6 CBZ36600.1 - 2.7e-24 85.3 0.0 4.1e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 CBZ36600.1 - 3.4e-10 39.8 0.0 1.5e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.10 CBZ36600.1 - 1.8e-08 34.2 0.0 2.5e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CBZ36600.1 - 4.7e-06 26.5 0.0 6.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CBZ36600.1 - 6e-06 26.7 0.0 9.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CBZ36600.1 - 0.00018 21.4 0.0 0.00056 19.8 0.0 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CBZ36600.1 - 0.00078 19.6 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CBZ36600.1 - 0.025 14.3 0.1 0.058 13.2 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin Glutaredoxin PF00462.24 CBZ36600.1 - 0.038 14.2 0.1 0.58 10.4 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin CP12 PF02672.15 CBZ36602.1 - 0.00054 20.7 1.5 0.00069 20.3 1.5 1.2 1 0 0 1 1 1 1 CP12 domain HEPN_SAV_6107 PF18726.1 CBZ36602.1 - 0.0056 17.2 0.9 0.006 17.1 0.9 1.1 1 0 0 1 1 1 1 SAV_6107-like HEPN Peptidase_M8 PF01457.16 CBZ36604.1 - 8.2e-130 434.0 0.0 1.8e-129 432.9 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M20 PF01546.28 CBZ36606.1 - 5.4e-21 75.2 0.1 8.5e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ36606.1 - 8e-09 35.4 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain CRAL_TRIO PF00650.20 CBZ36608.1 - 3.4e-50 169.9 0.0 5.1e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Glyco_hydro_1 PF00232.18 CBZ36608.1 - 0.066 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 T3SS_needle_reg PF09025.10 CBZ36608.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator CRAL_TRIO PF00650.20 CBZ36609.1 - 4e-46 156.6 0.0 6.6e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBZ36609.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 CBZ36610.1 - 7.5e-39 133.0 0.0 1.2e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBZ36610.1 - 0.08 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain VPS38 PF17649.1 CBZ36611.1 - 0.058 12.3 0.0 0.073 11.9 0.0 1.0 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Tis11B_N PF04553.12 CBZ36616.1 - 0.1 13.2 6.9 0.27 11.8 4.3 2.7 2 1 1 3 3 3 0 Tis11B like protein, N terminus tRNA_lig_CPD PF08302.11 CBZ36618.1 - 3.8e-10 39.7 0.0 3.7e-09 36.4 0.0 2.3 1 1 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 CBZ36618.1 - 0.00036 20.7 0.0 0.0052 16.9 0.0 2.2 1 1 0 1 1 1 1 tRNA ligase kinase domain AAA_15 PF13175.6 CBZ36618.1 - 0.00099 18.9 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CBZ36618.1 - 0.0015 18.7 0.0 0.0055 16.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ36618.1 - 0.0019 18.5 0.0 0.18 12.1 0.0 3.8 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 CBZ36618.1 - 0.0038 17.7 0.0 0.011 16.3 0.0 1.7 2 0 0 2 2 1 1 ABC transporter ATP_bind_1 PF03029.17 CBZ36618.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_21 PF13304.6 CBZ36618.1 - 0.018 14.9 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CBZ36618.1 - 0.037 13.8 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CBZ36618.1 - 0.062 13.7 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SWM_repeat PF13753.6 CBZ36618.1 - 0.11 12.6 0.3 0.28 11.3 0.3 1.6 1 0 0 1 1 1 0 Putative flagellar system-associated repeat AAA_18 PF13238.6 CBZ36618.1 - 0.13 12.8 0.0 0.42 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Aldo_ket_red PF00248.21 CBZ36620.1 - 2.1e-49 168.3 0.1 1.9e-47 161.9 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HEAT_2 PF13646.6 CBZ36622.1 - 5.4e-06 26.7 20.5 0.0018 18.6 0.1 5.4 5 0 0 5 5 5 2 HEAT repeats DUF3807 PF12720.7 CBZ36623.1 - 0.43 10.8 6.8 1.8 8.8 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) ECH_1 PF00378.20 CBZ36631.1 - 2.2e-46 158.2 0.0 2.7e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ36631.1 - 5.4e-10 39.3 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_M1 PF01433.20 CBZ36632.1 - 7e-09 35.6 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CBZ36632.1 - 3e-08 34.1 0.0 4.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DA1-like PF12315.8 CBZ36632.1 - 0.0021 17.5 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein DA1 Fes1 PF08609.10 CBZ36633.1 - 0.0092 16.8 2.4 0.038 14.9 0.6 2.4 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 Arf PF00025.21 CBZ36634.1 - 8.8e-75 250.0 0.2 1e-74 249.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBZ36634.1 - 5.2e-15 55.7 0.1 7.1e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ36634.1 - 4.6e-14 52.3 0.0 5.5e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBZ36634.1 - 2.2e-13 50.1 0.0 2.4e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CBZ36634.1 - 9.7e-12 44.7 0.4 4.1e-08 32.8 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CBZ36634.1 - 2.8e-07 30.1 0.0 3.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ36634.1 - 2e-05 24.6 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBZ36634.1 - 0.001 18.4 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.27 CBZ36634.1 - 0.023 14.2 0.1 0.099 12.2 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CBZ36634.1 - 0.15 12.2 0.1 0.17 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain PEMT PF04191.13 CBZ36635.1 - 7.4e-31 106.7 2.6 1.2e-30 106.0 1.6 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase S1-P1_nuclease PF02265.16 CBZ36637.1 - 6.3e-66 222.8 0.0 9.3e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease DUF4690 PF15756.5 CBZ36637.1 - 0.17 12.5 2.6 0.18 12.4 0.5 2.0 2 0 0 2 2 2 0 Small Novel Rich in Cartilage SNF2_N PF00176.23 CBZ36638.1 - 8.8e-41 139.8 0.2 3.4e-40 137.9 0.2 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ36638.1 - 1.7e-11 44.5 0.0 8.5e-08 32.5 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ36638.1 - 2.3e-06 27.7 0.0 5.4e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CBZ36638.1 - 0.0055 15.9 0.0 0.7 9.0 0.0 2.3 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.6 CBZ36638.1 - 0.012 15.9 0.1 0.16 12.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ36638.1 - 0.12 12.8 0.1 0.37 11.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain SWI2_SNF2 PF18766.1 CBZ36638.1 - 0.22 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase ECH_1 PF00378.20 CBZ36639.1 - 9.6e-44 149.6 0.0 1.2e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ36639.1 - 2e-08 34.1 0.0 3.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Hydrolase_6 PF13344.6 CBZ36640.1 - 5.9e-20 71.3 0.0 2e-19 69.6 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBZ36640.1 - 1.1e-18 67.0 0.0 3e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 CBZ36640.1 - 7e-05 22.5 0.0 0.00029 20.5 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase PF00702.26 CBZ36640.1 - 0.00024 21.5 0.1 0.072 13.4 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CBZ36640.1 - 0.0032 17.6 0.1 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase WD40 PF00400.32 CBZ36643.1 - 0.1 13.5 0.3 55 4.9 0.0 4.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Cation_efflux PF01545.21 CBZ36645.1 - 2.3e-41 141.7 10.2 3.1e-41 141.3 10.2 1.2 1 0 0 1 1 1 1 Cation efflux family DUF5407 PF17401.2 CBZ36647.1 - 0.091 13.0 0.2 0.16 12.3 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5407) Barttin PF15462.6 CBZ36647.1 - 0.12 12.1 1.4 0.13 12.0 0.3 1.6 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) ER-remodelling PF14755.6 CBZ36650.1 - 0.0028 18.0 0.1 0.0047 17.2 0.1 1.3 1 0 0 1 1 1 1 Intracellular membrane remodeller Lipase_3 PF01764.25 CBZ36652.1 - 1.9e-36 125.0 0.0 4.6e-36 123.8 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CBZ36652.1 - 6.1e-05 22.4 0.0 9.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 CBZ36652.1 - 0.00074 19.1 0.5 0.0084 15.7 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CBZ36652.1 - 0.025 15.2 0.1 0.035 14.7 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Na_K-ATPase PF00287.18 CBZ36653.1 - 0.22 10.7 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain PRK PF00485.18 CBZ36654.1 - 6.4e-12 45.6 0.0 7.7e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family zf-C2H2_4 PF13894.6 CBZ36654.1 - 0.014 16.2 0.5 2.9 9.0 0.0 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Fer2 PF00111.27 CBZ36655.1 - 3.7e-11 42.8 1.2 5e-11 42.4 1.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain HECT_2 PF09814.9 CBZ36655.1 - 0.018 13.9 0.2 0.02 13.7 0.2 1.1 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF5021 PF16424.5 CBZ36655.1 - 0.069 13.0 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5021) Fer2 PF00111.27 CBZ36656.1 - 2.7e-09 36.8 2.5 3.9e-09 36.3 2.5 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NifU PF01106.17 CBZ36656.1 - 0.15 12.2 0.7 0.3 11.3 0.7 1.5 1 0 0 1 1 1 0 NifU-like domain Fer2 PF00111.27 CBZ36657.1 - 8.8e-10 38.4 1.4 1.2e-09 38.0 1.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain SurE PF01975.17 CBZ36657.1 - 0.024 14.4 0.0 0.031 14.1 0.0 1.1 1 0 0 1 1 1 0 Survival protein SurE Fer2 PF00111.27 CBZ36658.1 - 2.6e-08 33.7 1.0 5.3e-08 32.7 1.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PepSY_TM PF03929.16 CBZ36659.1 - 0.0046 16.7 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 PepSY-associated TM region NIPSNAP PF07978.13 CBZ36660.1 - 0.11 12.8 0.3 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 NIPSNAP XkdW PF09636.10 CBZ36661.1 - 0.22 11.6 0.0 0.63 10.1 0.0 1.7 1 0 0 1 1 1 0 XkdW protein UCR_hinge PF02320.16 CBZ36663.1 - 6.9e-18 64.6 3.6 7.7e-18 64.5 3.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Leucyl-specific PF14795.6 CBZ36663.1 - 0.055 13.5 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain TerD PF02342.18 CBZ36664.1 - 3.9e-14 52.6 0.0 0.00018 21.0 0.0 3.3 3 0 0 3 3 3 3 TerD domain Calreticulin PF00262.18 CBZ36665.1 - 1.5e-74 251.1 11.8 2.2e-53 181.4 3.3 2.1 1 1 1 2 2 2 2 Calreticulin family Sialidase PF02973.16 CBZ36665.1 - 0.085 12.3 0.1 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Sialidase, N-terminal domain FAM219A PF15260.6 CBZ36665.1 - 0.1 13.0 0.4 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein family FAM219A RNA_pol_Rpb1_5 PF04998.17 CBZ36666.1 - 6.8e-98 327.3 0.2 1.1e-97 326.7 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CBZ36666.1 - 1.7e-95 319.9 1.6 1.5e-94 316.8 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CBZ36666.1 - 2e-70 236.3 0.6 5.3e-70 234.9 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CBZ36666.1 - 1.1e-49 168.9 1.0 1.9e-49 168.1 1.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 CBZ36666.1 - 2.9e-39 134.5 0.0 7.3e-39 133.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CBZ36666.1 - 5.6e-29 100.2 0.1 1.9e-28 98.6 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 CBZ36666.1 - 3e-23 82.3 0.6 3e-23 82.3 0.6 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 PspA_IM30 PF04012.12 CBZ36666.1 - 0.03 13.9 1.9 0.078 12.5 1.9 1.6 1 0 0 1 1 1 0 PspA/IM30 family CRCB PF02537.15 CBZ36667.1 - 1.2e-27 96.0 17.6 1.1e-13 51.3 0.6 2.6 2 1 1 3 3 3 2 CrcB-like protein, Camphor Resistance (CrcB) Metallophos PF00149.28 CBZ36668.1 - 1.6e-37 130.0 0.3 2e-37 129.7 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ36668.1 - 8.2e-08 32.6 0.1 2.7e-07 30.9 0.1 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Pyr_redox_2 PF07992.14 CBZ36669.1 - 3.3e-38 131.6 0.1 4.4e-38 131.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBZ36669.1 - 6.6e-16 58.5 0.5 4.7e-15 55.8 0.0 2.6 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBZ36669.1 - 4.8e-15 55.9 0.0 1.7e-14 54.1 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 CBZ36669.1 - 2.4e-05 23.8 0.0 0.0001 21.7 0.0 2.0 3 0 0 3 3 3 1 ThiF family K_oxygenase PF13434.6 CBZ36669.1 - 5.9e-05 22.4 0.0 0.001 18.3 0.0 2.2 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CBZ36669.1 - 0.0002 20.8 0.0 0.00042 19.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CBZ36669.1 - 0.00026 21.0 0.1 0.00046 20.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 CBZ36669.1 - 0.00078 19.1 1.0 0.69 9.4 0.0 3.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.22 CBZ36669.1 - 0.0052 15.9 0.0 0.22 10.5 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A ApbA PF02558.16 CBZ36669.1 - 0.017 14.7 0.0 0.05 13.2 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 CBZ36669.1 - 0.027 13.2 0.5 0.56 8.8 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.18 CBZ36669.1 - 0.027 14.7 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.24 CBZ36669.1 - 0.063 12.4 1.0 1.7 7.6 0.2 2.5 3 0 0 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.21 CBZ36669.1 - 0.064 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 CBZ36669.1 - 0.079 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 CBZ36669.1 - 0.12 12.6 0.1 0.32 11.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBZ36670.1 - 3.5e-43 147.9 0.0 5e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBZ36670.1 - 2.6e-20 72.7 0.2 9.6e-20 70.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBZ36670.1 - 2.9e-17 63.0 0.2 8.2e-13 48.7 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CBZ36670.1 - 2.3e-10 40.4 0.0 2.3e-10 40.4 0.0 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ36670.1 - 3.7e-09 36.7 1.4 0.00038 20.6 0.3 2.9 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CBZ36670.1 - 3.9e-08 32.8 1.2 8.8e-06 25.0 0.4 2.9 2 1 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 CBZ36670.1 - 5.3e-07 29.5 2.3 0.00014 21.5 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 CBZ36670.1 - 7.8e-07 28.1 2.4 8.1e-06 24.8 0.2 2.8 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 CBZ36670.1 - 1.9e-06 27.4 8.2 0.00036 19.9 0.5 2.9 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBZ36670.1 - 2.8e-06 26.7 0.7 2.8e-06 26.7 0.7 2.4 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 CBZ36670.1 - 5.2e-06 25.9 0.4 0.0016 17.7 0.0 2.8 3 0 0 3 3 3 1 Thi4 family Lycopene_cycl PF05834.12 CBZ36670.1 - 8.3e-06 25.1 0.5 0.00073 18.7 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 CBZ36670.1 - 3.6e-05 23.2 1.2 0.0026 17.1 0.0 3.1 3 1 0 3 3 3 1 FAD binding domain PALP PF00291.25 CBZ36670.1 - 0.00016 21.2 0.1 0.00032 20.2 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.21 CBZ36670.1 - 0.0002 20.8 0.2 0.46 9.7 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 CBZ36670.1 - 0.0011 18.3 0.1 0.0031 16.9 0.1 1.7 1 0 0 1 1 1 1 ThiF family K_oxygenase PF13434.6 CBZ36670.1 - 0.0032 16.7 0.0 0.21 10.7 0.0 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CBZ36670.1 - 0.033 14.2 0.5 0.37 10.8 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.18 CBZ36670.1 - 0.039 14.2 2.1 1.4 9.2 0.1 3.2 3 0 0 3 3 3 0 TrkA-N domain Utp14 PF04615.13 CBZ36673.1 - 0.044 12.4 3.2 0.064 11.8 3.2 1.2 1 0 0 1 1 1 0 Utp14 protein Mucin PF01456.17 CBZ36673.1 - 0.27 11.2 134.0 0.027 14.5 65.9 4.7 2 1 2 4 4 4 0 Mucin-like glycoprotein KAR9 PF08580.10 CBZ36673.1 - 2.9 6.3 14.9 4.7 5.6 14.9 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Endomucin PF07010.12 CBZ36673.1 - 4.9 7.0 46.5 12 5.8 46.5 1.6 1 0 0 1 1 1 0 Endomucin RIFIN PF02009.16 CBZ36673.1 - 6.2 6.6 8.5 13 5.5 8.5 1.5 1 0 0 1 1 1 0 Rifin GREB1 PF15782.5 CBZ36673.1 - 9.8 3.1 8.4 14 2.7 8.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LRR_4 PF12799.7 CBZ36674.1 - 0.0007 19.9 1.1 0.0013 19.0 1.1 1.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) DNA_pol_A_exo1 PF01612.20 CBZ36676.1 - 2e-05 24.4 0.1 8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease MORN PF02493.20 CBZ36677.1 - 2.1e-29 99.7 47.1 6.9e-09 35.1 0.7 7.9 8 0 0 8 8 8 7 MORN repeat Kinesin PF00225.23 CBZ36677.1 - 3.2e-17 62.4 0.0 2e-16 59.8 0.0 2.1 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ36677.1 - 0.00075 19.5 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF3048_C PF17479.2 CBZ36677.1 - 0.024 15.0 5.9 1.1 9.7 1.4 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain DUF3253 PF11625.8 CBZ36677.1 - 0.092 13.0 0.2 0.39 11.0 0.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) FTO_CTD PF12934.7 CBZ36677.1 - 0.23 11.2 2.6 0.19 11.5 0.4 2.1 2 0 0 2 2 2 0 FTO C-terminal domain RVT_N PF13655.6 CBZ36677.1 - 3.2 8.1 4.9 1.2 9.4 0.1 2.7 3 0 0 3 3 3 0 N-terminal domain of reverse transcriptase Bap31 PF05529.12 CBZ36678.1 - 0.0064 16.4 3.5 0.0081 16.0 3.5 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region RCC1 PF00415.18 CBZ36679.1 - 3e-27 95.0 11.1 2.6e-13 50.4 0.0 7.5 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ36679.1 - 5.8e-19 67.4 16.6 0.00044 20.0 0.1 5.1 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat EMP24_GP25L PF01105.24 CBZ36680.1 - 4.9e-35 121.1 0.0 6.5e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD COPIIcoated_ERV PF07970.12 CBZ36681.1 - 2.6e-65 220.4 0.0 4e-65 219.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBZ36681.1 - 9.7e-26 89.9 0.2 2.4e-25 88.7 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Cytochrom_B561 PF03188.16 CBZ36681.1 - 0.091 12.9 0.2 0.26 11.4 0.1 1.8 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 DUF725 PF05267.12 CBZ36682.1 - 0.064 13.2 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF725) SesA PF17107.5 CBZ36682.1 - 0.065 13.4 0.8 0.11 12.6 0.8 1.3 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Exonuc_VII_L PF02601.15 CBZ36682.1 - 0.2 11.2 6.7 0.29 10.7 6.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TFIIA PF03153.13 CBZ36682.1 - 1.3 9.0 9.2 1.6 8.6 9.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PROL5-SMR PF15621.6 CBZ36682.1 - 2 9.0 9.7 1 9.9 7.1 1.8 1 1 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family RRM_1 PF00076.22 CBZ36684.1 - 1e-11 44.5 0.0 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4778 PF16008.5 CBZ36685.1 - 0.1 12.7 5.5 0.093 12.8 4.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4778) Arf PF00025.21 CBZ36687.1 - 1.2e-77 259.4 0.1 1.3e-77 259.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBZ36687.1 - 6e-14 51.9 0.0 7.3e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBZ36687.1 - 1.7e-13 50.5 0.4 3.1e-09 36.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CBZ36687.1 - 2.1e-13 50.5 0.0 2.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ36687.1 - 1e-12 48.0 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CBZ36687.1 - 3.6e-09 36.3 0.0 4.4e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ36687.1 - 9.4e-05 22.5 0.0 0.00015 21.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CBZ36687.1 - 0.0075 15.6 0.1 0.01 15.2 0.1 1.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase cobW PF02492.19 CBZ36687.1 - 0.046 13.3 0.1 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CBZ36687.1 - 0.059 13.5 0.2 0.11 12.6 0.2 1.6 1 1 0 1 1 1 0 AAA domain Prok-TraM PF09228.10 CBZ36688.1 - 0.056 13.8 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic Transcriptional repressor TraM DUF1771 PF08590.10 CBZ36689.1 - 3.1e-19 69.1 6.7 6.6e-19 68.0 6.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) KH_1 PF00013.29 CBZ36689.1 - 2.2e-08 33.8 0.7 4.4e-08 32.8 0.7 1.5 1 0 0 1 1 1 1 KH domain Smr PF01713.21 CBZ36689.1 - 4.4e-06 26.9 1.4 1.1e-05 25.6 0.0 2.3 2 1 1 3 3 3 1 Smr domain KH_2 PF07650.17 CBZ36689.1 - 0.0053 16.6 0.8 0.02 14.7 0.2 2.2 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 CBZ36689.1 - 0.17 11.8 0.6 0.48 10.3 0.5 1.9 1 1 0 1 1 1 0 KH domain Sec2p PF06428.11 CBZ36689.1 - 2.7 8.0 8.0 4.1 7.5 0.7 2.7 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p Maf1 PF09174.10 CBZ36690.1 - 1.7e-27 96.7 0.0 2.3e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Tryp_alpha_amyl PF00234.22 CBZ36690.1 - 0.04 14.3 0.0 0.069 13.6 0.0 1.3 1 0 0 1 1 1 0 Protease inhibitor/seed storage/LTP family Reprolysin_4 PF13583.6 CBZ36690.1 - 0.18 11.4 0.1 0.28 10.8 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like PriC PF07445.12 CBZ36691.1 - 0.23 11.4 3.0 0.64 9.9 2.9 1.7 1 1 0 1 1 1 0 Primosomal replication protein priC PGA2 PF07543.12 CBZ36691.1 - 6 6.8 11.2 20 5.1 11.2 1.9 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2244 PF10003.9 CBZ36692.1 - 3.2 7.4 10.9 0.045 13.4 1.4 2.5 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) Ribosomal_L12 PF00542.19 CBZ36693.1 - 4.8e-17 62.1 1.3 9.6e-17 61.1 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Pkinase PF00069.25 CBZ36694.1 - 6.3e-58 196.2 0.0 1.5e-57 195.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36694.1 - 2.8e-28 98.9 0.0 6e-28 97.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ36694.1 - 0.0028 17.0 0.0 0.016 14.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CBZ36694.1 - 0.011 15.3 0.2 0.051 13.2 0.2 2.1 1 1 1 2 2 2 0 RIO1 family Pox_ser-thr_kin PF05445.11 CBZ36694.1 - 0.14 11.1 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase L71 PF02448.15 CBZ36694.1 - 0.18 12.3 0.1 0.5 10.8 0.1 1.7 1 0 0 1 1 1 0 L71 family APH PF01636.23 CBZ36694.1 - 3 7.7 7.0 0.39 10.6 0.6 2.6 2 2 1 3 3 3 0 Phosphotransferase enzyme family Spc7 PF08317.11 CBZ36694.1 - 3.8 6.3 17.5 0.14 11.1 1.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 CBZ36694.1 - 5.3 6.5 11.9 23 4.4 12.0 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Aldo_ket_red PF00248.21 CBZ36696.1 - 2.2e-56 191.2 0.0 3.9e-55 187.1 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Clathrin PF00637.20 CBZ36697.1 - 2.2e-08 34.1 2.1 6e-08 32.7 0.7 2.2 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 CBZ36697.1 - 0.047 13.9 0.0 0.095 13.0 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal RNA_pol_Rpb4 PF03874.16 CBZ36697.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb4 zf-RING_UBOX PF13445.6 CBZ36697.1 - 0.18 11.9 10.5 0.42 10.7 5.5 3.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 CBZ36697.1 - 0.23 11.5 2.5 0.83 9.7 2.5 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2396 PF09654.10 CBZ36697.1 - 0.26 11.4 0.1 0.26 11.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) zf-rbx1 PF12678.7 CBZ36697.1 - 0.7 10.2 7.0 2.2 8.6 7.0 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBZ36697.1 - 9.8 6.2 15.5 4.9 7.2 10.5 2.7 2 0 0 2 2 2 0 zinc-RING finger domain Nup54 PF13874.6 CBZ36698.1 - 4.3e-23 82.0 1.0 4.3e-23 82.0 1.0 2.1 2 1 1 3 3 3 1 Nucleoporin complex subunit 54 Nup54_C PF18437.1 CBZ36698.1 - 0.023 14.6 0.4 0.065 13.1 0.4 1.8 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain DUF5586 PF17824.1 CBZ36699.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5586) DUF4677 PF15726.5 CBZ36700.1 - 0.0058 16.8 0.2 0.0083 16.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4677) DUF4588 PF15251.6 CBZ36700.1 - 0.0061 16.4 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Inositol_P PF00459.25 CBZ36701.1 - 1.2e-13 51.2 0.6 6.6e-13 48.8 0.6 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L7Ae PF01248.26 CBZ36702.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SQS_PSY PF00494.19 CBZ36703.1 - 3.2e-45 154.7 0.0 4.5e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase NUDIX PF00293.28 CBZ36704.1 - 5.9e-14 52.2 0.0 1.1e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 CBZ36704.1 - 6.4e-09 35.3 3.6 1.3e-08 34.4 3.6 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 CBZ36704.1 - 0.0015 18.5 0.9 0.0032 17.5 0.9 1.4 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 CBZ36704.1 - 0.035 14.1 0.1 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RecR PF02132.15 CBZ36704.1 - 0.044 13.4 0.1 0.089 12.4 0.1 1.5 1 0 0 1 1 1 0 RecR protein zinc_ribbon_2 PF13240.6 CBZ36704.1 - 0.15 11.8 4.4 1.2 9.0 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HscB_4_cys PF18256.1 CBZ36704.1 - 0.15 11.9 2.8 0.32 10.8 2.8 1.6 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif DMA PF03474.14 CBZ36704.1 - 0.79 9.4 2.5 4.4 7.0 0.0 2.6 3 0 0 3 3 3 0 DMRTA motif Pkinase PF00069.25 CBZ36705.1 - 6.2e-63 212.6 0.0 8.3e-63 212.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36705.1 - 1.4e-42 145.8 0.0 2.1e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ36705.1 - 2e-08 33.9 0.0 1.2e-06 28.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PH PF00169.29 CBZ36705.1 - 1.6e-05 25.3 0.0 3.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 CBZ36705.1 - 0.00047 19.2 0.1 0.00067 18.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DUF1636 PF07845.11 CBZ36705.1 - 0.045 14.2 0.3 0.12 12.9 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1636) Kdo PF06293.14 CBZ36705.1 - 0.09 12.1 0.2 0.43 9.9 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Carboxyl_trans PF01039.22 CBZ36706.1 - 1e-129 433.4 0.0 1.5e-129 432.9 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 CBZ36706.1 - 1.7e-53 182.0 0.0 3.4e-52 177.7 0.1 2.3 2 1 0 2 2 2 1 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 CBZ36706.1 - 9e-49 165.8 0.0 1.7e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBZ36706.1 - 7.9e-29 100.4 0.0 2e-28 99.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBZ36706.1 - 1.8e-21 76.2 0.0 1.8e-20 73.0 0.0 2.7 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBZ36706.1 - 3e-07 30.2 0.0 8.2e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CBZ36706.1 - 0.00027 20.5 0.0 0.00059 19.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBZ36706.1 - 0.0017 18.0 0.0 0.0063 16.1 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CBZ36706.1 - 0.0089 15.8 0.0 0.027 14.3 0.0 1.8 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CBZ36706.1 - 0.038 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain SMK-1 PF04802.15 CBZ36707.1 - 2.2e-08 34.2 0.0 3.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 HMW1C_N PF18071.1 CBZ36708.1 - 0.09 12.6 0.1 0.54 10.1 0.1 2.5 1 0 0 1 1 1 0 HMW1C N-terminal DUF4407 PF14362.6 CBZ36709.1 - 0.0015 17.9 10.2 0.0028 17.0 10.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DivIC PF04977.15 CBZ36709.1 - 0.075 12.8 5.3 26 4.7 0.0 3.7 3 0 0 3 3 3 0 Septum formation initiator NPV_P10 PF05531.12 CBZ36709.1 - 0.17 12.4 0.7 41 4.7 0.2 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 CBZ36709.1 - 0.28 11.5 1.8 27 5.1 0.0 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0242 PF06785.11 CBZ36709.1 - 0.3 11.2 7.2 0.65 10.1 2.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 CBZ36709.1 - 0.6 10.2 3.9 11 6.1 0.4 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) HALZ PF02183.18 CBZ36709.1 - 1.4 9.2 6.2 0.7 10.2 0.5 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper TMF_TATA_bd PF12325.8 CBZ36709.1 - 2.3 8.4 20.8 0.92 9.8 4.6 3.7 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 CBZ36709.1 - 4.6 7.9 5.9 12 6.6 2.5 2.9 2 1 0 2 2 2 0 Initiation control protein YabA F_actin_bind PF08919.10 CBZ36710.1 - 0.00027 21.0 8.3 0.068 13.3 0.6 2.6 1 1 1 2 2 2 2 F-actin binding MCPsignal PF00015.21 CBZ36710.1 - 0.014 15.2 0.0 0.045 13.6 0.0 1.9 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CENP-H PF05837.12 CBZ36710.1 - 0.022 15.2 7.8 0.022 15.2 7.8 2.6 1 1 0 2 2 2 0 Centromere protein H (CENP-H) DUF4972 PF16342.5 CBZ36710.1 - 0.033 13.9 2.3 0.069 12.8 1.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) Prominin PF05478.11 CBZ36710.1 - 0.32 8.9 1.8 0.49 8.3 1.8 1.3 1 0 0 1 1 1 0 Prominin FapA PF03961.13 CBZ36710.1 - 2.5 6.6 5.4 3.4 6.1 5.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 CBZ36710.1 - 3.6 6.7 8.2 2.7 7.2 5.9 1.6 1 1 1 2 2 2 0 TMPIT-like protein LMBR1 PF04791.16 CBZ36710.1 - 9 5.1 6.4 12 4.6 6.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Per1 PF04080.13 CBZ36714.1 - 0.018 14.8 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Per1-like family DUF948 PF06103.11 CBZ36714.1 - 0.085 13.1 0.2 0.38 11.1 0.2 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Phg_2220_C PF09524.10 CBZ36714.1 - 0.16 12.0 4.4 0.88 9.7 0.2 2.3 1 1 1 2 2 2 0 Conserved phage C-terminus (Phg_2220_C) DUF1515 PF07439.11 CBZ36714.1 - 0.34 11.0 6.1 0.66 10.0 3.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Cyclase PF04199.13 CBZ36715.1 - 1.6e-16 60.8 0.0 2.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Zip PF02535.22 CBZ36716.1 - 1.8e-08 34.0 3.4 2.1e-08 33.8 3.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 CBZ36717.1 - 2.8e-41 141.9 5.7 4.1e-41 141.3 5.7 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter BTB_2 PF02214.22 CBZ36718.1 - 0.00034 20.9 0.0 0.00087 19.6 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Peptidase_M16 PF00675.20 CBZ36719.1 - 2.5e-31 108.7 0.0 4.7e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 CBZ36719.1 - 2.2e-29 102.6 0.1 1.4e-25 90.1 0.1 2.5 3 0 0 3 3 3 2 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CBZ36719.1 - 9.5e-13 48.6 0.0 8.1e-08 32.5 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain DnaJ PF00226.31 CBZ36720.1 - 1.1e-16 60.7 0.1 1.7e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Autophagy_act_C PF03987.15 CBZ36721.1 - 0.15 12.7 0.1 0.72 10.5 0.0 2.2 2 1 0 2 2 2 0 Autophagocytosis associated protein, active-site domain SUV3_C PF12513.8 CBZ36722.1 - 0.033 14.1 2.0 0.12 12.3 0.2 3.2 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal PKcGMP_CC PF16808.5 CBZ36722.1 - 2 8.4 18.0 2.2 8.2 1.3 5.2 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PEMT PF04191.13 CBZ36723.1 - 5.1e-52 174.7 11.0 6.7e-30 103.6 1.0 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase CPSase_L_D2 PF02786.17 CBZ36724.1 - 1.8e-63 213.9 0.0 3.5e-63 212.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CBZ36724.1 - 9.5e-44 148.4 0.1 2.4e-43 147.1 0.0 1.7 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CBZ36724.1 - 3.2e-34 117.3 0.0 7.9e-34 116.0 0.0 1.7 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CBZ36724.1 - 1.5e-14 53.6 1.8 2.8e-14 52.7 1.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CBZ36724.1 - 2.5e-11 43.5 0.0 6.7e-11 42.1 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CBZ36724.1 - 1.6e-10 40.8 0.1 2.8e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CBZ36724.1 - 0.00013 21.7 0.1 0.00082 19.2 0.0 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CBZ36724.1 - 0.0047 17.0 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 CBZ36724.1 - 0.0084 15.7 0.0 2.5 7.7 0.0 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 CBZ36724.1 - 0.027 13.8 0.0 0.078 12.2 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 CBZ36724.1 - 0.05 14.3 0.2 9 7.1 0.0 3.0 3 0 0 3 3 3 0 HlyD family secretion protein RnfC_N PF13375.6 CBZ36724.1 - 0.14 12.1 1.0 0.55 10.2 0.4 2.2 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain FAD_binding_3 PF01494.19 CBZ36725.1 - 0.09 12.0 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain PaRep2a PF07903.11 CBZ36725.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 PaRep2a protein Robl_LC7 PF03259.17 CBZ36726.1 - 5.7e-07 29.2 0.0 8.5e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 Roadblock/LC7 domain LDcluster4 PF18306.1 CBZ36727.1 - 0.17 11.4 0.9 0.39 10.3 0.9 1.5 1 0 0 1 1 1 0 SLOG cluster4 family Pkinase PF00069.25 CBZ36728.1 - 4.1e-61 206.7 0.0 5.5e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36728.1 - 1.5e-41 142.4 0.0 2.1e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBZ36728.1 - 1.6e-12 47.8 0.1 3.4e-12 46.8 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CBZ36728.1 - 2.7e-08 34.2 0.3 7.4e-07 29.6 0.3 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 CBZ36728.1 - 2.7e-07 30.2 0.0 5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ36728.1 - 0.024 13.4 0.1 0.097 11.4 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase PH_11 PF15413.6 CBZ36728.1 - 0.22 11.9 2.7 18 5.8 2.7 2.6 1 1 0 1 1 1 0 Pleckstrin homology domain MFS_1 PF07690.16 CBZ36729.1 - 2.1e-21 76.2 37.4 1.4e-17 63.7 26.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ36729.1 - 2.8e-10 40.1 9.0 2.8e-10 40.1 9.0 2.5 2 1 0 2 2 2 1 Nodulin-like TssO PF17561.2 CBZ36729.1 - 0.91 9.6 6.5 0.23 11.6 0.3 2.7 3 0 0 3 3 3 0 Type VI secretion system, TssO UPF0242 PF06785.11 CBZ36729.1 - 9.1 6.3 8.5 2.8 8.0 2.7 3.0 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus DUF19 PF01579.18 CBZ36735.1 - 0.11 12.3 8.0 0.13 12.1 5.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF19) DUF4245 PF14030.6 CBZ36735.1 - 0.43 10.6 3.3 0.39 10.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) TrbM PF07424.11 CBZ36735.1 - 2.2 8.2 10.2 4 7.4 3.0 2.9 1 1 2 3 3 3 0 TrbM WXG100 PF06013.12 CBZ36735.1 - 4.7 7.5 10.9 1.1 9.5 1.1 4.0 4 0 0 4 4 4 0 Proteins of 100 residues with WXG Torus PF16131.5 CBZ36736.1 - 0.32 11.7 2.0 1.7 9.4 0.8 2.5 2 1 0 2 2 2 0 Torus domain Torus PF16131.5 CBZ36737.1 - 0.14 12.8 0.6 0.35 11.6 0.1 1.9 2 0 0 2 2 2 0 Torus domain zf-CCCH PF00642.24 CBZ36737.1 - 0.43 10.6 0.2 0.43 10.6 0.2 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) WD40 PF00400.32 CBZ36738.1 - 1.8e-18 66.5 5.1 0.025 15.4 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ36738.1 - 1.4e-05 25.3 0.7 0.64 10.4 0.0 3.7 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SNARE PF05739.19 CBZ36740.1 - 1.5e-10 40.9 1.8 1.4e-09 37.8 0.0 2.7 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 CBZ36740.1 - 5.8e-05 22.9 11.7 0.00053 19.7 11.7 2.3 1 1 0 1 1 1 1 Syntaxin Nup54 PF13874.6 CBZ36740.1 - 0.0051 16.9 0.9 0.0051 16.9 0.9 2.2 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 DUF4208 PF13907.6 CBZ36740.1 - 0.0069 16.8 0.7 5.4 7.5 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4208) DUF2935 PF11155.8 CBZ36740.1 - 0.017 15.5 0.0 1.2 9.5 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) HsbA PF12296.8 CBZ36740.1 - 0.11 13.0 1.0 0.55 10.7 0.1 2.3 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 CBZ36740.1 - 0.29 11.2 5.7 2.2 8.3 0.2 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TraD_N PF12615.8 CBZ36740.1 - 0.4 11.5 0.2 0.4 11.5 0.2 2.5 3 0 0 3 3 2 0 F sex factor protein N terminal DUF16 PF01519.16 CBZ36740.1 - 1.2 9.7 8.3 0.42 11.1 0.8 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF16 Sec8_exocyst PF04048.14 CBZ36740.1 - 1.5 8.7 6.1 0.95 9.3 0.2 2.8 2 1 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF883 PF05957.13 CBZ36740.1 - 8.2 7.1 8.7 1.2 9.8 1.4 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) NMT PF01233.19 CBZ36741.1 - 3.3e-67 225.3 0.0 5.8e-67 224.5 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 CBZ36741.1 - 3.2e-64 216.3 0.4 5.2e-64 215.6 0.0 1.5 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DUF3432 PF11914.8 CBZ36742.1 - 0.013 15.7 3.3 0.028 14.7 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) TMEM239 PF15841.5 CBZ36742.1 - 0.034 14.0 0.6 0.06 13.2 0.6 1.4 1 0 0 1 1 1 0 Transmembrane protein 239 family NIF PF03031.18 CBZ36743.1 - 3.3e-26 91.9 0.0 3.6e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mito_carr PF00153.27 CBZ36744.1 - 1.2e-38 130.9 2.1 2.5e-14 52.9 0.0 4.6 3 2 1 4 4 4 4 Mitochondrial carrier protein Pkinase PF00069.25 CBZ36745.1 - 7.3e-58 196.0 0.0 9.4e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36745.1 - 6.5e-28 97.7 0.0 9.3e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ36745.1 - 1.9e-05 23.6 0.0 4.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CBZ36745.1 - 0.00032 20.1 0.1 0.00051 19.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBZ36745.1 - 0.0026 17.1 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CBZ36745.1 - 0.02 13.9 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CBZ36745.1 - 0.042 13.8 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Arm PF00514.23 CBZ36747.1 - 1.4e-37 126.6 28.7 1.8e-07 31.0 0.0 16.6 17 1 0 17 17 17 9 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 CBZ36747.1 - 1.5e-07 31.1 0.1 0.068 12.6 0.0 5.1 4 2 0 5 5 5 2 Armadillo-like Atx10homo_assoc PF09759.9 CBZ36747.1 - 0.0015 18.5 0.8 5 7.2 0.0 5.1 6 1 0 6 6 6 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 CBZ36747.1 - 0.038 14.3 6.6 25 5.5 0.3 5.9 5 1 0 5 5 5 0 HEAT repeat DUF383 PF04063.14 CBZ36747.1 - 0.043 13.5 0.0 45 3.6 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF383) HEAT_EZ PF13513.6 CBZ36747.1 - 0.1 13.1 11.3 21 5.7 0.0 7.2 7 2 0 7 7 7 0 HEAT-like repeat Spc7 PF08317.11 CBZ36747.1 - 0.36 9.6 4.6 0.58 9.0 4.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 CBZ36747.1 - 1.1 9.4 7.3 2.5 8.2 7.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Utp14 PF04615.13 CBZ36748.1 - 4.3e-117 392.7 44.4 4.3e-117 392.7 44.4 1.7 1 1 1 2 2 2 1 Utp14 protein LRR_9 PF14580.6 CBZ36751.1 - 2.7e-20 72.6 1.7 7.7e-20 71.1 1.7 1.7 1 1 0 1 1 1 1 Leucine-rich repeat CCDC-167 PF15188.6 CBZ36751.1 - 0.024 15.0 3.4 0.024 15.0 3.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 LRR_4 PF12799.7 CBZ36751.1 - 0.028 14.9 0.8 10 6.7 0.0 3.5 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) GvpG PF05120.12 CBZ36751.1 - 0.12 12.4 2.2 0.24 11.4 2.2 1.5 1 0 0 1 1 1 0 Gas vesicle protein G SpoIIIAH PF12685.7 CBZ36751.1 - 0.12 12.2 4.1 0.18 11.6 4.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein K_channel_TID PF07941.11 CBZ36751.1 - 0.52 10.8 5.4 1.4 9.4 5.4 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF4407 PF14362.6 CBZ36751.1 - 0.76 9.1 10.3 1.1 8.6 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rtf2 PF04641.12 CBZ36751.1 - 0.82 9.0 0.0 0.82 9.0 0.0 2.5 1 1 2 3 3 3 0 Rtf2 RING-finger DUF1936 PF09151.10 CBZ36752.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) HSP70 PF00012.20 CBZ36753.1 - 7.9e-08 30.9 0.2 0.00049 18.4 0.1 2.4 2 0 0 2 2 2 2 Hsp70 protein PKI PF02827.16 CBZ36754.1 - 0.048 13.9 0.1 0.22 11.7 0.1 2.2 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor Baculo_PEP_C PF04513.12 CBZ36754.1 - 0.074 13.1 5.4 2.8 8.0 0.8 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 CBZ36754.1 - 0.17 11.4 11.0 0.13 11.8 6.3 2.7 2 1 0 2 2 2 0 Intermediate filament protein Fib_alpha PF08702.10 CBZ36754.1 - 0.2 11.8 5.3 2.5 8.3 0.3 3.4 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Herpes_UL6 PF01763.16 CBZ36754.1 - 0.2 10.1 1.6 0.22 10.0 0.8 1.5 1 1 0 1 1 1 0 Herpesvirus UL6 like WXG100 PF06013.12 CBZ36754.1 - 2 8.7 0.0 2 8.7 0.0 4.5 5 1 1 6 6 6 0 Proteins of 100 residues with WXG Rtt106 PF08512.12 CBZ36755.1 - 1.2e-11 44.9 0.0 1.6e-09 38.1 0.0 3.0 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SSrecog PF03531.14 CBZ36755.1 - 3.2e-05 23.7 0.0 0.0001 22.1 0.0 1.9 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) YL1 PF05764.13 CBZ36755.1 - 0.09 12.9 34.5 0.13 12.4 34.5 1.2 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 CBZ36755.1 - 1.1 7.5 32.4 1.6 6.9 32.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CBZ36755.1 - 1.9 6.6 33.9 2.3 6.3 33.9 1.1 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 CBZ36755.1 - 2.4 8.1 27.3 3.2 7.7 26.5 1.5 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 CBZ36755.1 - 3.3 7.0 34.3 4.3 6.7 34.3 1.1 1 0 0 1 1 1 0 SDA1 Apt1 PF10351.9 CBZ36755.1 - 7.7 5.2 18.4 10 4.9 18.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 CBZ36755.1 - 8.7 5.0 14.7 13 4.4 14.7 1.1 1 0 0 1 1 1 0 Presenilin MPM1 PF17234.2 CBZ36756.1 - 0.21 11.9 4.0 0.52 10.6 4.0 1.6 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Peroxin-3 PF04882.12 CBZ36756.1 - 0.96 8.4 10.8 0.96 8.4 0.8 2.3 2 0 0 2 2 2 0 Peroxin-3 Dynein_light PF01221.18 CBZ36757.1 - 6.7e-41 138.5 0.9 7.5e-41 138.4 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.20 CBZ36757.1 - 0.018 15.0 0.0 0.021 14.7 0.0 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Imm48 PF15574.6 CBZ36757.1 - 0.065 13.0 0.1 0.087 12.6 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 48 Ectatomin PF06457.11 CBZ36757.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Ectatomin LRR_4 PF12799.7 CBZ36758.1 - 3.4e-05 24.1 2.8 0.0077 16.6 0.1 3.9 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ36758.1 - 0.0021 18.0 0.9 38 4.7 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich repeat DUF4200 PF13863.6 CBZ36758.1 - 0.13 12.7 13.8 2.3 8.6 1.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) LRR_8 PF13855.6 CBZ36758.1 - 0.59 9.9 5.2 13 5.6 0.0 3.5 4 0 0 4 4 4 0 Leucine rich repeat AAA_13 PF13166.6 CBZ36758.1 - 0.61 8.7 4.6 0.84 8.2 3.9 1.5 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 CBZ36760.1 - 4.4e-67 226.2 0.0 6.2e-67 225.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36760.1 - 2e-50 171.5 0.0 3e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ36760.1 - 2.1e-05 24.0 0.0 5.6e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CBZ36760.1 - 0.017 14.7 0.2 0.042 13.4 0.2 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CBZ36760.1 - 0.065 12.6 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Big_9 PF17963.1 CBZ36761.1 - 0.59 10.9 0.0 0.59 10.9 0.0 3.8 5 2 1 6 6 6 0 Bacterial Ig domain B9-C2 PF07162.11 CBZ36762.1 - 4.2e-34 118.2 0.0 5.3e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein LRR_8 PF13855.6 CBZ36764.1 - 3.8e-13 49.0 11.1 7e-07 28.9 2.3 5.6 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 CBZ36764.1 - 2.2e-08 34.2 10.2 0.086 13.3 0.4 5.2 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CBZ36764.1 - 0.0092 16.0 8.9 7.6 6.9 0.7 6.5 8 0 0 8 8 8 1 Leucine Rich repeat LRR_9 PF14580.6 CBZ36764.1 - 0.03 13.8 0.6 2.2 7.8 0.0 2.8 2 1 1 3 3 3 0 Leucine-rich repeat LRR_1 PF00560.33 CBZ36764.1 - 0.062 13.9 9.9 2.8 8.8 0.3 5.8 6 1 0 6 6 6 0 Leucine Rich Repeat TPR_19 PF14559.6 CBZ36765.1 - 3.4e-08 33.9 11.9 0.017 15.6 0.5 8.0 7 2 2 9 9 8 2 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 CBZ36765.1 - 3.2e-06 26.5 0.4 0.023 13.8 0.0 4.2 3 2 1 4 4 4 1 Coatomer WD associated region Clathrin PF00637.20 CBZ36765.1 - 8.1e-06 25.8 0.2 5.6 6.8 0.0 5.5 4 2 1 5 5 5 1 Region in Clathrin and VPS Nic96 PF04097.14 CBZ36765.1 - 0.00017 20.2 2.9 0.38 9.1 0.0 4.0 2 1 2 4 4 4 1 Nup93/Nic96 TPR_7 PF13176.6 CBZ36765.1 - 0.0017 18.3 19.6 1.7 8.8 0.7 7.9 8 1 1 9 9 9 2 Tetratricopeptide repeat Nucleoporin_N PF08801.11 CBZ36765.1 - 0.0074 15.1 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like TPR_16 PF13432.6 CBZ36765.1 - 0.018 15.6 1.4 0.018 15.6 1.4 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 CBZ36765.1 - 0.024 14.9 0.1 0.99 9.7 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TPR_12 PF13424.6 CBZ36765.1 - 0.17 12.2 26.7 1.6 9.0 0.1 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat WD40 PF00400.32 CBZ36765.1 - 0.18 12.7 0.2 61 4.7 0.1 3.3 3 0 0 3 3 2 0 WD domain, G-beta repeat TPR_14 PF13428.6 CBZ36765.1 - 0.2 12.6 29.1 4.1 8.5 1.3 10.0 8 2 2 10 10 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ36765.1 - 0.28 11.1 18.6 12 5.9 3.0 7.1 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ36765.1 - 0.38 11.0 32.3 3.6 7.9 3.4 9.8 10 1 0 10 10 10 0 Tetratricopeptide repeat MIT PF04212.18 CBZ36765.1 - 0.39 10.8 17.4 8.8 6.5 0.4 6.0 7 0 0 7 7 7 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 CBZ36765.1 - 3.8 7.2 8.6 3.4 7.3 0.0 4.5 4 2 1 5 5 5 0 26S proteasome subunit RPN7 Cas9_Topo PF17894.1 CBZ36767.1 - 0.1 12.7 0.1 0.32 11.1 0.1 1.8 1 0 0 1 1 1 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 ARL2_Bind_BART PF11527.8 CBZ36768.1 - 0.18 12.0 0.0 0.84 9.8 0.0 2.1 1 1 0 1 1 1 0 The ARF-like 2 binding protein BART DUF4558 PF15104.6 CBZ36769.1 - 9.3 6.4 9.9 1.6 8.9 3.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4558) RHD3 PF05879.12 CBZ36771.1 - 1.1e-101 341.2 0.0 1.2e-89 301.5 0.0 3.2 2 1 1 3 3 3 3 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 CBZ36771.1 - 3.2e-05 24.1 0.1 6.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 CBZ36771.1 - 0.00029 21.1 0.1 0.00097 19.4 0.1 2.0 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBZ36771.1 - 0.0063 16.6 0.0 0.026 14.6 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Cgr1 PF03879.14 CBZ36772.1 - 0.41 11.1 3.3 0.67 10.3 3.3 1.3 1 0 0 1 1 1 0 Cgr1 family JAB PF01398.21 CBZ36773.1 - 3.2e-25 88.4 0.0 3.4e-24 85.1 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CBZ36773.1 - 2e-17 63.6 0.6 4.3e-17 62.5 0.6 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function ASL_C PF08328.11 CBZ36773.1 - 0.024 14.7 0.8 3.5 7.8 0.2 2.4 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal DEAD PF00270.29 CBZ36774.1 - 1.4e-46 158.5 0.0 2.3e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ36774.1 - 1.3e-32 112.4 0.0 4e-31 107.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CBZ36774.1 - 0.0022 17.2 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CBZ36774.1 - 0.051 13.9 0.0 0.42 10.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain GRIM-19 PF06212.12 CBZ36774.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 GRIM-19 protein TPR_19 PF14559.6 CBZ36775.1 - 0.0061 17.0 12.9 0.59 10.7 2.2 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ36775.1 - 0.63 10.4 26.4 1.1 9.6 0.3 6.4 5 2 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ36775.1 - 2 8.7 28.9 2.8 8.3 0.1 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ36775.1 - 6.1 6.8 12.6 5.7 6.9 1.3 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Kinesin PF00225.23 CBZ36776.1 - 9.6e-33 113.5 0.0 1.3e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain MORN PF02493.20 CBZ36776.1 - 8.1e-17 60.0 36.2 0.0015 18.3 0.2 7.4 7 0 0 7 7 7 5 MORN repeat Microtub_bd PF16796.5 CBZ36776.1 - 5.8e-10 39.3 0.0 9.9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding DUF1279 PF06916.13 CBZ36777.1 - 1.3e-07 32.1 0.1 2.2e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) WW PF00397.26 CBZ36777.1 - 0.00027 21.0 0.5 0.00061 19.8 0.5 1.6 1 0 0 1 1 1 1 WW domain Ribosomal_S5_C PF03719.15 CBZ36778.1 - 4.8e-25 86.8 0.0 7.7e-25 86.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CBZ36778.1 - 1.8e-21 75.9 0.3 3.7e-21 74.9 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Phage_tail_NK PF16532.5 CBZ36778.1 - 0.21 11.2 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales FoP_duplication PF13865.6 CBZ36778.1 - 0.34 11.5 6.3 0.7 10.5 6.3 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Aldo_ket_red PF00248.21 CBZ36779.1 - 4.5e-57 193.5 0.0 3.8e-55 187.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family LRR_6 PF13516.6 CBZ36780.1 - 3.7e-07 29.7 21.9 0.051 13.7 0.0 8.8 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 CBZ36780.1 - 0.00068 20.0 10.7 51 4.5 0.0 7.6 7 1 1 8 8 8 0 Leucine Rich repeats (2 copies) RTT107_BRCT_5 PF16770.5 CBZ36780.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain TMEM247 PF15444.6 CBZ36780.1 - 0.2 11.7 3.4 0.37 10.8 3.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 Mpp10 PF04006.12 CBZ36780.1 - 1.3 7.4 21.3 2.3 6.6 21.3 1.3 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 CBZ36780.1 - 7.8 4.6 22.7 13 3.8 22.7 1.3 1 0 0 1 1 1 0 Nop14-like family Rtf2 PF04641.12 CBZ36781.1 - 1.6e-23 83.4 0.3 1.3e-22 80.4 0.3 1.9 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 CBZ36781.1 - 0.00026 20.7 0.0 0.6 10.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 CBZ36781.1 - 0.01 15.9 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Corona_RPol_N PF06478.13 CBZ36782.1 - 0.048 12.7 0.0 0.054 12.5 0.0 1.0 1 0 0 1 1 1 0 Coronavirus RPol N-terminus FOG_N PF15888.5 CBZ36782.1 - 0.084 13.3 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Folded gastrulation N-terminus Ras PF00071.22 CBZ36784.1 - 5.3e-56 188.7 0.1 6.2e-56 188.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ36784.1 - 2.3e-35 121.4 0.0 3.3e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ36784.1 - 2.9e-15 56.2 0.0 3.4e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CBZ36784.1 - 1.1e-07 31.6 0.2 1.3e-06 28.1 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ36784.1 - 2.3e-05 24.4 0.0 4.3e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CBZ36784.1 - 2.6e-05 23.7 0.0 3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CBZ36784.1 - 0.00044 20.2 0.0 0.031 14.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 CBZ36784.1 - 0.00058 19.2 0.0 0.00088 18.6 0.0 1.2 1 0 0 1 1 1 1 Septin PduV-EutP PF10662.9 CBZ36784.1 - 0.0027 17.5 0.1 0.01 15.6 0.1 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 CBZ36784.1 - 0.021 15.1 0.0 0.047 14.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain NACHT PF05729.12 CBZ36784.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain TniB PF05621.11 CBZ36784.1 - 0.049 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_7 PF12775.7 CBZ36784.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CBZ36784.1 - 0.072 13.5 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CBZ36784.1 - 0.11 12.1 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain YwhD PF08741.10 CBZ36784.1 - 0.12 12.0 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 YwhD family CDC50 PF03381.15 CBZ36786.1 - 5.5e-51 173.7 0.0 6.7e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Promethin PF16015.5 CBZ36786.1 - 0.091 12.7 2.9 6.1 6.8 0.1 2.2 2 0 0 2 2 2 0 Promethin Profilin PF00235.19 CBZ36787.1 - 1.5e-42 144.8 0.3 1.9e-42 144.5 0.3 1.1 1 0 0 1 1 1 1 Profilin TauE PF01925.19 CBZ36789.1 - 4.6e-23 82.1 23.6 7e-15 55.3 0.0 3.0 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE Herpes_LMP1 PF05297.11 CBZ36789.1 - 1.2 8.3 9.8 0.45 9.6 3.0 2.9 2 1 1 3 3 3 0 Herpesvirus latent membrane protein 1 (LMP1) CHCH PF06747.13 CBZ36790.1 - 0.00025 21.1 6.2 0.045 13.9 0.2 2.6 2 1 0 2 2 2 2 CHCH domain MTCP1 PF08991.10 CBZ36790.1 - 0.00096 19.3 3.5 0.00096 19.3 3.5 2.2 2 1 0 2 2 2 1 Mature-T-Cell Proliferation I type Cmc1 PF08583.10 CBZ36790.1 - 0.037 14.0 9.3 0.25 11.4 0.4 2.9 2 1 1 3 3 3 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 CBZ36790.1 - 0.71 10.2 6.5 0.99 9.7 0.4 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.12 CBZ36790.1 - 0.76 10.1 12.3 8.5 6.7 0.1 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0203) CX9C PF16860.5 CBZ36790.1 - 0.94 9.5 9.1 0.5 10.4 0.5 3.0 2 1 1 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, GCK PF07802.11 CBZ36790.1 - 2 8.9 7.2 0.73 10.3 0.8 2.4 1 1 2 3 3 3 0 GCK domain DUF3716 PF12511.8 CBZ36790.1 - 4.5 7.4 12.7 1.2e+02 2.9 9.2 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3716) zf-C3HC4_3 PF13920.6 CBZ36791.1 - 2.4e-05 24.1 17.5 4e-05 23.4 17.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SKG6 PF08693.10 CBZ36791.1 - 0.68 9.4 3.2 1.1 8.7 3.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DEAD PF00270.29 CBZ36792.1 - 4.4e-34 117.8 0.1 1.1e-33 116.5 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ36792.1 - 3.1e-27 95.1 0.0 1.5e-26 92.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ36792.1 - 8.4e-07 29.1 0.1 1.9e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CBZ36792.1 - 0.29 10.5 0.0 0.29 10.5 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit PBP1_TM PF14812.6 CBZ36793.1 - 0.6 10.5 12.1 2.1 8.8 12.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YL1 PF05764.13 CBZ36793.1 - 0.64 10.1 16.9 1.6 8.8 16.9 1.7 1 1 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.13 CBZ36793.1 - 3 7.7 5.6 21 4.9 2.6 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region DnaJ PF00226.31 CBZ36794.1 - 8.1e-10 38.7 0.0 2.5e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 DnaJ domain TRPM_tetra PF16519.5 CBZ36795.1 - 0.29 11.3 2.8 0.2 11.8 0.3 2.1 2 0 0 2 2 2 0 Tetramerisation domain of TRPM KxDL PF10241.9 CBZ36795.1 - 0.33 11.2 5.4 0.09 13.1 0.8 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein Vac_Fusion PF02346.16 CBZ36795.1 - 0.37 10.5 2.5 0.73 9.5 0.2 2.5 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 WD40 PF00400.32 CBZ36796.1 - 8.8e-10 39.0 1.2 0.0012 19.6 0.4 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat MFS18 PF17352.2 CBZ36796.1 - 0.02 15.3 0.4 0.04 14.3 0.4 1.4 1 0 0 1 1 1 0 Male Flower Specific protein 18 Ge1_WD40 PF16529.5 CBZ36796.1 - 0.065 12.2 0.1 22 3.8 0.0 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MMS1_N PF10433.9 CBZ36796.1 - 0.11 11.1 0.0 3.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term ANAPC4_WD40 PF12894.7 CBZ36796.1 - 0.16 12.3 0.1 20 5.6 0.0 3.4 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain AMMECR1 PF01871.17 CBZ36798.1 - 4.1e-46 156.6 0.0 4.8e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 DSPc PF00782.20 CBZ36799.1 - 1.7e-12 47.3 0.0 3.3e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ36799.1 - 1.6e-10 41.0 0.0 3.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CBZ36799.1 - 4.5e-05 23.2 0.0 8.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CBZ36799.1 - 8.5e-05 22.7 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CBZ36799.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family AKAP7_NLS PF10469.9 CBZ36800.1 - 4.1e-44 151.0 0.0 5e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 CBZ36800.1 - 1.4e-07 31.6 0.0 2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily EF-hand_7 PF13499.6 CBZ36801.1 - 2.2e-11 44.0 1.5 0.00012 22.4 0.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ36801.1 - 2.6e-11 42.5 0.9 0.00044 20.0 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CBZ36801.1 - 9.2e-09 34.2 2.2 0.0064 16.0 0.1 4.0 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 CBZ36801.1 - 8.3e-07 28.8 7.0 0.0015 18.4 1.1 4.4 2 1 3 5 5 5 3 EF-hand domain pair EFhand_Ca_insen PF08726.10 CBZ36801.1 - 0.00029 20.8 0.2 0.19 11.9 0.0 2.4 2 1 0 2 2 2 2 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 CBZ36801.1 - 0.0031 17.0 3.2 0.27 10.8 0.1 3.1 4 0 0 4 4 4 2 EF hand YqeY PF09424.10 CBZ36801.1 - 0.099 12.7 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Yqey-like protein Trypsin_2 PF13365.6 CBZ36802.1 - 0.015 16.2 0.0 0.033 15.1 0.0 1.6 1 1 0 1 1 1 0 Trypsin-like peptidase domain Kinesin PF00225.23 CBZ36803.1 - 1.2e-100 336.7 0.3 1.2e-100 336.7 0.3 3.2 4 0 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ36803.1 - 8.3e-27 93.9 2.5 5.9e-26 91.2 0.0 3.2 3 0 0 3 3 3 1 Microtubule binding DUF3800 PF12686.7 CBZ36803.1 - 0.052 14.2 0.0 24 5.6 0.0 4.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) zf-C2H2_9 PF16293.5 CBZ36803.1 - 0.17 11.8 6.5 0.032 14.1 1.1 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) AAA_16 PF13191.6 CBZ36803.1 - 3.5 8.0 0.0 3.5 8.0 0.0 4.3 4 3 0 4 4 4 0 AAA ATPase domain S4 PF01479.25 CBZ36804.1 - 6.6e-05 22.5 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain UQ_con PF00179.26 CBZ36805.1 - 2.5e-35 121.1 0.0 4e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GEN1_C PF18380.1 CBZ36805.1 - 0.5 11.3 3.6 2.6 9.0 4.5 1.8 2 1 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Mut7-C PF01927.16 CBZ36806.1 - 9.5e-46 155.5 0.5 1.6e-45 154.8 0.5 1.3 1 0 0 1 1 1 1 Mut7-C RNAse domain LSM PF01423.22 CBZ36807.1 - 5.4e-12 45.2 0.1 7.3e-12 44.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ36807.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Pan3_PK PF18101.1 CBZ36808.1 - 6.8e-40 136.2 0.6 9.6e-40 135.8 0.6 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain LRR_4 PF12799.7 CBZ36809.1 - 1.7e-12 47.3 7.5 0.00014 22.1 0.0 4.2 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ36809.1 - 2.4e-12 46.4 6.5 1.2e-08 34.5 3.3 4.2 4 1 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 CBZ36809.1 - 0.00068 19.2 0.2 0.95 8.9 0.0 3.2 3 0 0 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 CBZ36809.1 - 0.02 14.9 2.1 4.9 7.5 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ36809.1 - 0.055 14.0 0.2 17 6.4 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat 4PPT_N PF17837.1 CBZ36810.1 - 0.00084 19.4 0.3 0.0029 17.7 0.3 2.0 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain RRM_1 PF00076.22 CBZ36811.1 - 1.1e-10 41.2 0.8 6.2e-05 22.7 0.2 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ36811.1 - 0.018 14.6 0.0 0.13 11.9 0.0 2.0 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2967 PF11179.8 CBZ36811.1 - 0.049 11.8 2.5 0.071 11.2 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Cyclin_N PF00134.23 CBZ36812.1 - 4.3e-08 33.0 0.6 9.3e-08 31.9 0.6 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain RIC1 PF07064.13 CBZ36813.1 - 3.8e-43 147.7 0.0 6.5e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 CBZ36813.1 - 0.0011 19.3 0.0 0.061 13.6 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CBZ36814.1 - 5.8e-47 160.3 0.0 9.7e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36814.1 - 4.3e-30 104.9 0.0 7.6e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ36814.1 - 0.0013 18.7 0.0 0.0037 17.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ36814.1 - 0.057 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CBZ36814.1 - 0.058 12.4 0.1 0.096 11.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 CBZ36818.1 - 1.2e-49 169.1 0.0 1.9e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36818.1 - 1.5e-35 122.8 0.0 2.8e-35 121.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1356 PF07092.12 CBZ36818.1 - 0.058 12.7 0.1 7.6 5.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) HemY_N PF07219.13 CBZ36818.1 - 0.2 11.8 2.2 2.1 8.6 1.2 2.3 2 0 0 2 2 2 0 HemY protein N-terminus Cyclin PF08613.11 CBZ36819.1 - 8.4e-24 84.8 0.4 1.1e-23 84.3 0.4 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBZ36819.1 - 6.5e-10 38.8 0.2 8.3e-10 38.5 0.2 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain RRM_8 PF11835.8 CBZ36821.1 - 1.2e-07 31.8 0.0 2.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 RRM-like domain RRM_1 PF00076.22 CBZ36821.1 - 0.0022 17.8 0.0 0.044 13.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBZ36822.1 - 1.2e-12 47.5 0.0 3.2e-05 23.7 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CBZ36822.1 - 0.00023 20.9 0.0 0.00081 19.2 0.0 1.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_8 PF11835.8 CBZ36822.1 - 0.0074 16.5 0.0 0.023 14.9 0.0 1.8 1 1 0 1 1 1 1 RRM-like domain RRM_5 PF13893.6 CBZ36822.1 - 0.021 14.4 0.0 3.7 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBZ36822.1 - 0.05 13.6 0.0 17 5.5 0.0 3.2 3 0 0 3 3 3 0 RNA binding motif Tmemb_55A PF09788.9 CBZ36823.1 - 0.0018 17.4 0.5 0.0042 16.2 0.5 1.5 1 0 0 1 1 1 1 Transmembrane protein 55A tRNA-synt_2d PF01409.20 CBZ36824.1 - 1.2e-79 267.3 0.2 1.7e-79 266.7 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD1 PF18552.1 CBZ36824.1 - 6.8e-09 35.4 0.1 1.7e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 1 PheRS_DBD3 PF18553.1 CBZ36824.1 - 3.1e-06 27.4 0.1 6.7e-05 23.1 0.0 2.9 3 0 0 3 3 3 1 PheRS DNA binding domain 3 PheRS_DBD2 PF18554.1 CBZ36824.1 - 0.00011 22.1 0.5 0.00024 21.0 0.5 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 CBZ36824.1 - 0.00062 18.9 0.4 0.0021 17.2 0.2 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 CBZ36824.1 - 0.0019 17.6 0.2 1.6 8.1 0.0 2.7 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 CBZ36824.1 - 0.0031 17.5 0.1 0.0084 16.1 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HTH_24 PF13412.6 CBZ36824.1 - 0.048 13.2 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.6 CBZ36824.1 - 0.16 11.8 0.2 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain CTP_transf_like PF01467.26 CBZ36825.1 - 5.1e-45 153.2 0.1 8.3e-27 94.1 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CBZ36825.1 - 1.7e-05 24.7 0.7 0.21 11.4 0.0 3.4 2 1 0 2 2 2 2 FAD synthetase Bcr-Abl_Oligo PF09036.10 CBZ36826.1 - 1.3 9.1 5.9 0.67 10.0 1.8 2.1 1 1 1 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Abhydrolase_6 PF12697.7 CBZ36827.1 - 7.3e-16 59.4 0.0 8.9e-16 59.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBZ36827.1 - 1.5e-10 40.7 0.1 2.2e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ36827.1 - 1.1e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CBZ36827.1 - 0.00054 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 CBZ36827.1 - 0.0021 17.8 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 CBZ36827.1 - 0.0045 15.9 0.0 0.017 14.1 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Lipase_3 PF01764.25 CBZ36827.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 CBZ36827.1 - 0.014 14.8 0.0 0.034 13.6 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family PAF-AH_p_II PF03403.13 CBZ36827.1 - 0.023 13.2 0.1 0.066 11.7 0.0 1.7 3 0 0 3 3 3 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_9 PF10081.9 CBZ36827.1 - 0.026 13.6 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF900 PF05990.12 CBZ36827.1 - 0.056 12.9 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase PF00151.19 CBZ36827.1 - 0.059 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Lipase Abhydrolase_5 PF12695.7 CBZ36827.1 - 0.073 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CBZ36827.1 - 0.1 12.5 0.6 0.21 11.4 0.0 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold V_ATPase_I PF01496.19 CBZ36828.1 - 9.1e-246 817.7 0.6 1.1e-245 817.4 0.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family GMC_oxred_N PF00732.19 CBZ36829.1 - 9.2e-07 28.5 0.2 0.00055 19.4 0.0 3.1 3 1 0 3 3 3 2 GMC oxidoreductase DAO PF01266.24 CBZ36829.1 - 1.3e-06 28.2 0.4 1.7e-05 24.6 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CBZ36829.1 - 9.7e-05 21.6 1.2 0.0024 17.0 0.3 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CBZ36829.1 - 0.00061 20.0 0.2 0.0015 18.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBZ36829.1 - 0.0029 16.9 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ36829.1 - 0.0039 16.3 0.2 0.0062 15.6 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 CBZ36829.1 - 0.014 14.1 0.3 0.021 13.5 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.14 CBZ36829.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 CBZ36829.1 - 0.034 14.1 0.1 0.077 13.0 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 CBZ36829.1 - 0.049 12.9 0.4 0.17 11.2 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 CBZ36829.1 - 0.12 11.6 0.2 0.24 10.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CBZ36829.1 - 0.26 10.3 0.7 0.38 9.8 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CLASP_N PF12348.8 CBZ36830.1 - 4.8e-11 42.7 0.6 3.4e-09 36.6 0.2 2.5 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 CBZ36830.1 - 0.0023 18.0 20.2 10 6.7 0.0 8.1 7 0 0 7 7 7 3 HEAT repeat Cnd1 PF12717.7 CBZ36830.1 - 0.003 17.6 0.0 2.6 8.1 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 T_Ag_DNA_bind PF02217.16 CBZ36830.1 - 0.67 10.6 2.1 1.6 9.4 2.1 1.6 1 0 0 1 1 1 0 Origin of replication binding protein DUF3022 PF11226.8 CBZ36830.1 - 5 7.6 8.1 0.29 11.6 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) SNase PF00565.17 CBZ36831.1 - 1.6e-53 179.7 2.7 1.6e-15 57.5 0.0 5.3 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 CBZ36831.1 - 4.3e-16 59.1 0.0 8.4e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Tudor domain Agenet PF05641.12 CBZ36831.1 - 0.0055 17.2 0.5 0.047 14.2 0.0 2.7 3 0 0 3 3 3 1 Agenet domain DUF4537 PF15057.6 CBZ36831.1 - 0.012 15.6 0.0 0.048 13.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) UQ_con PF00179.26 CBZ36832.1 - 3.4e-40 136.9 0.0 4.7e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF3630 PF12305.8 CBZ36832.1 - 0.081 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3630) Peptidase_C2 PF00648.21 CBZ36833.1 - 1.1e-06 27.9 0.0 3.7e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Calpain family cysteine protease DGF-1_C PF11040.8 CBZ36833.1 - 1.2 9.2 5.6 1.1 9.3 0.1 3.4 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus RRM_1 PF00076.22 CBZ36834.1 - 0.0052 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vps23_core PF09454.10 CBZ36835.1 - 1.1e-17 63.7 0.0 2.6e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Vps23 core domain Exonuc_VII_L PF02601.15 CBZ36835.1 - 0.039 13.5 1.3 0.057 13.0 1.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit WD40 PF00400.32 CBZ36836.1 - 4.1e-08 33.7 3.9 1.3e-05 25.8 0.3 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat Cpn60_TCP1 PF00118.24 CBZ36837.1 - 1.2e-152 509.0 1.4 1.4e-152 508.8 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Y_phosphatase2 PF03162.13 CBZ36838.1 - 7.9e-22 77.6 0.0 5.7e-21 74.8 0.0 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Pkinase PF00069.25 CBZ36839.1 - 8.6e-33 113.8 0.4 1.3e-26 93.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36839.1 - 4.7e-17 62.1 0.3 1e-16 61.0 0.3 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CBZ36839.1 - 0.0021 17.8 0.2 0.0096 15.6 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CBZ36839.1 - 0.0042 15.9 0.0 0.0087 14.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase DUF747 PF05346.11 CBZ36839.1 - 0.038 13.5 0.6 0.062 12.7 0.6 1.2 1 0 0 1 1 1 0 Eukaryotic membrane protein family APH PF01636.23 CBZ36839.1 - 0.19 11.6 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Maf PF02545.14 CBZ36840.1 - 1.3e-17 64.2 0.0 1.5e-17 64.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein ATP11 PF06644.11 CBZ36840.1 - 0.064 13.0 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 ATP11 protein NECFESHC PF16621.5 CBZ36841.1 - 0.075 13.0 0.2 0.24 11.4 0.2 1.9 1 0 0 1 1 1 0 SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 Thioredoxin_4 PF13462.6 CBZ36841.1 - 0.1 12.7 2.6 0.29 11.3 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin DUF1722 PF08349.11 CBZ36841.1 - 2.6 8.3 4.6 4 7.7 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) Syntaxin_2 PF14523.6 CBZ36841.1 - 3.2 8.2 15.7 13 6.2 0.2 4.1 4 0 0 4 4 4 0 Syntaxin-like protein DUF445 PF04286.12 CBZ36841.1 - 3.4 7.4 15.0 0.13 12.0 2.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF445) Metallophos_2 PF12850.7 CBZ36842.1 - 1.3e-14 54.7 0.1 1.6e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 CBZ36842.1 - 0.068 12.5 0.0 2.8 7.2 0.0 2.1 1 1 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily WD40 PF00400.32 CBZ36843.1 - 2.6e-08 34.4 11.2 0.15 13.0 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ36843.1 - 0.0022 18.3 0.1 0.12 12.7 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain LSM PF01423.22 CBZ36844.1 - 4.8e-14 51.8 0.1 5.6e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ36844.1 - 0.0086 16.2 0.0 0.0097 16.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain HECT PF00632.25 CBZ36846.1 - 7.6e-70 235.8 0.0 1.1e-69 235.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ZZ PF00569.17 CBZ36846.1 - 0.00026 20.7 9.2 0.00026 20.7 9.2 1.7 2 0 0 2 2 2 1 Zinc finger, ZZ type Utp14 PF04615.13 CBZ36846.1 - 0.79 8.2 4.5 0.16 10.6 0.6 1.6 2 0 0 2 2 2 0 Utp14 protein DNA_pol_phi PF04931.13 CBZ36846.1 - 1.6 6.8 6.0 3.2 5.8 6.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi CRM1_C PF08767.11 CBZ36847.1 - 4.5e-61 206.8 0.8 4.5e-61 206.8 0.8 2.9 4 0 0 4 4 4 1 CRM1 C terminal CRM1_repeat_2 PF18784.1 CBZ36847.1 - 6.2e-27 93.0 1.5 1.9e-26 91.5 1.5 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 Xpo1 PF08389.12 CBZ36847.1 - 1.7e-26 93.0 5.8 2.4e-26 92.6 0.9 3.8 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 CBZ36847.1 - 2.3e-23 82.0 3.9 2.5e-23 81.9 1.4 2.5 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 CBZ36847.1 - 2.4e-10 40.2 0.2 2.3e-09 37.0 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 CBZ36847.1 - 1.5e-09 37.2 1.1 5.3e-09 35.5 1.1 2.0 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat DUF4473 PF14747.6 CBZ36847.1 - 0.00084 19.8 0.4 5.1 7.7 0.1 4.0 3 1 1 4 4 4 1 Domain of unknown function (DUF4473) Peptidase_C27 PF05407.12 CBZ36847.1 - 0.039 14.0 1.6 0.16 12.0 1.0 2.3 3 0 0 3 3 3 0 Rubella virus endopeptidase DUF1765 PF08578.10 CBZ36847.1 - 0.18 12.3 5.0 2.6 8.5 0.4 4.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1765) Mito_carr PF00153.27 CBZ36848.1 - 3e-48 161.7 1.5 1.6e-16 60.0 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CBZ36849.1 - 2.1e-49 165.4 2.2 2.4e-18 65.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PPR_2 PF13041.6 CBZ36851.1 - 0.0011 19.1 0.3 26 5.1 0.0 4.7 5 1 1 6 6 6 3 PPR repeat family ELO PF01151.18 CBZ36853.1 - 7.2e-50 169.8 18.2 9.6e-50 169.4 18.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Ank PF00023.30 CBZ36855.1 - 2.3e-06 27.8 2.4 0.023 15.1 0.4 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CBZ36855.1 - 7.3e-06 26.4 0.2 2.2e-05 24.9 0.2 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ36855.1 - 1.2e-05 25.5 1.0 3.1e-05 24.2 1.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CBZ36855.1 - 1.2e-05 25.8 0.0 2.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ36855.1 - 2.1e-05 24.5 0.3 0.044 14.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat CSN8_PSD8_EIF3K PF10075.9 CBZ36857.1 - 1.3e-26 93.3 0.0 2.1e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HhH-GPD PF00730.25 CBZ36857.1 - 0.084 13.3 0.1 0.23 11.9 0.0 1.7 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein PPR_2 PF13041.6 CBZ36858.1 - 6.6e-40 135.1 22.6 2.9e-14 53.0 0.0 12.6 8 5 6 14 14 14 8 PPR repeat family PPR_3 PF13812.6 CBZ36858.1 - 4.4e-34 116.3 12.5 7.6e-15 54.7 0.2 9.6 6 3 3 10 10 10 8 Pentatricopeptide repeat domain PPR_long PF17177.4 CBZ36858.1 - 3.3e-15 56.0 11.5 2.9e-05 23.5 0.0 5.9 3 2 3 6 6 6 4 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CBZ36858.1 - 4.3e-14 51.7 18.4 6.6e-07 29.2 0.0 9.9 12 0 0 12 12 12 3 PPR repeat PPR_1 PF12854.7 CBZ36858.1 - 3.3e-11 42.7 24.2 1.6e-09 37.3 0.0 8.3 9 0 0 9 9 9 2 PPR repeat COX5A PF02284.16 CBZ36858.1 - 4.7e-05 23.3 0.2 0.43 10.6 0.1 2.9 1 1 1 2 2 2 2 Cytochrome c oxidase subunit Va ECSIT PF06239.11 CBZ36858.1 - 0.0013 17.9 2.1 2.2 7.3 0.1 4.1 3 1 1 4 4 4 2 Evolutionarily conserved signalling intermediate in Toll pathway RPM2 PF08579.11 CBZ36858.1 - 0.018 15.5 3.1 24 5.3 0.7 4.7 2 1 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) DUF4407 PF14362.6 CBZ36859.1 - 0.047 13.0 8.6 1.4 8.2 1.6 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Pox_A_type_inc PF04508.12 CBZ36859.1 - 0.1 12.5 4.0 0.085 12.7 1.7 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat LapA_dom PF06305.11 CBZ36859.1 - 0.21 11.4 2.7 10 6.0 0.0 2.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RCDG1 PF15725.5 CBZ36859.1 - 1.2 9.6 9.3 0.27 11.7 5.2 2.1 2 0 0 2 2 2 0 Renal cancer differentiation gene 1 protein Flagellin_N PF00669.20 CBZ36859.1 - 4.3 7.4 9.9 1.2 9.2 0.2 3.3 4 0 0 4 4 4 0 Bacterial flagellin N-terminal helical region Clusterin PF01093.17 CBZ36859.1 - 7.5 5.5 9.7 5.3 6.0 5.3 2.4 2 1 0 2 2 2 0 Clusterin ArfGap PF01412.18 CBZ36860.1 - 1.2e-27 96.3 0.0 2.1e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Apolipoprotein PF01442.18 CBZ36860.1 - 0.07 13.0 0.6 0.1 12.4 0.6 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain TF_Zn_Ribbon PF08271.12 CBZ36860.1 - 0.075 12.6 2.1 0.13 11.7 2.1 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding PHTB1_C PF14728.6 CBZ36861.1 - 8.3e-105 350.9 0.1 1.1e-104 350.6 0.1 1.1 1 0 0 1 1 1 1 PTHB1 C-terminus PHTB1_N PF14727.6 CBZ36861.1 - 3e-91 306.8 0.0 8.6e-66 223.0 0.0 2.1 2 0 0 2 2 2 2 PTHB1 N-terminus BBS2_Mid PF14783.6 CBZ36861.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region YqfQ PF14181.6 CBZ36861.1 - 2.2 8.4 4.7 12 6.1 4.5 2.2 1 1 0 1 1 1 0 YqfQ-like protein UCH PF00443.29 CBZ36862.1 - 2.7e-33 115.5 0.0 3.7e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ36862.1 - 1.8e-11 44.2 0.0 2.1e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CRAL_TRIO PF00650.20 CBZ36863.1 - 7e-41 139.6 0.0 1e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain GOLD_2 PF13897.6 CBZ36863.1 - 0.00017 22.1 0.1 0.22 12.0 0.0 2.3 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking CRAL_TRIO_N PF03765.15 CBZ36863.1 - 0.16 12.1 0.2 0.4 10.9 0.2 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain UBA_4 PF14555.6 CBZ36863.1 - 0.17 11.7 0.1 12 5.9 0.0 2.4 2 0 0 2 2 2 0 UBA-like domain CRAL_TRIO PF00650.20 CBZ36864.1 - 3.2e-30 105.0 0.0 6.6e-30 103.9 0.0 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBZ36864.1 - 0.00043 20.4 0.0 0.0011 19.1 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain SHS2_Rpb7-N PF03876.17 CBZ36865.1 - 2.7e-14 53.3 0.0 4.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase PF00069.25 CBZ36866.1 - 2.4e-08 33.7 0.0 4.1e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36866.1 - 5.8e-06 25.8 0.0 8.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ36866.1 - 9.2e-05 22.5 0.0 0.0002 21.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBZ36866.1 - 0.0065 16.1 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 CBZ36866.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pep_deformylase PF01327.21 CBZ36867.1 - 2.7e-28 98.6 0.0 3.4e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase WLM PF08325.10 CBZ36868.1 - 2.4e-34 119.1 0.0 3.1e-32 112.2 0.0 2.1 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 CBZ36868.1 - 0.0023 18.0 1.1 0.0045 17.0 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 EHN PF06441.12 CBZ36869.1 - 6.9 7.1 7.7 1.1 9.6 2.1 2.5 3 0 0 3 3 3 0 Epoxide hydrolase N terminus Peptidase_C97 PF05903.14 CBZ36870.1 - 8e-17 61.5 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain CPSF_A PF03178.15 CBZ36871.1 - 1.9e-65 221.3 0.0 3.7e-65 220.4 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CBZ36871.1 - 6.8e-18 64.6 0.0 2.3e-12 46.3 0.0 3.6 3 1 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term LicD PF04991.13 CBZ36872.1 - 4.3e-08 33.6 0.0 7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 LicD family mRNA_cap_enzyme PF01331.19 CBZ36873.1 - 4e-08 33.3 0.0 7.1e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain ADK PF00406.22 CBZ36873.1 - 9.3e-07 29.1 0.0 2e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ36873.1 - 2.4e-06 28.0 0.0 9.2e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain mRNA_cap_C PF03919.15 CBZ36873.1 - 7.7e-06 26.5 0.0 1.6e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain AAA_18 PF13238.6 CBZ36873.1 - 1.1e-05 25.9 0.0 2.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBZ36873.1 - 0.0037 17.4 0.3 0.016 15.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 CBZ36873.1 - 0.0062 16.2 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.6 CBZ36873.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBZ36873.1 - 0.054 13.5 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBZ36873.1 - 0.088 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBZ36873.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBZ36873.1 - 0.16 11.3 0.1 0.83 8.9 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 CBZ36873.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 CBZ36874.1 - 0.003 18.1 0.0 0.0058 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ36874.1 - 0.0056 17.1 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CBZ36874.1 - 0.0061 16.7 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CBZ36874.1 - 0.013 15.9 0.1 0.029 14.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CBZ36874.1 - 0.097 13.1 0.1 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PAM2 PF07145.15 CBZ36874.1 - 0.21 11.3 1.5 0.79 9.5 1.5 2.0 1 0 0 1 1 1 0 Ataxin-2 C-terminal region FliT PF05400.13 CBZ36874.1 - 0.62 10.9 0.0 0.62 10.9 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein FliT DEAD PF00270.29 CBZ36877.1 - 3e-21 76.0 0.1 1e-20 74.2 0.1 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 CBZ36877.1 - 1.3e-18 67.1 0.0 7.4e-16 58.1 0.0 2.7 3 0 0 3 3 3 2 Sec63 Brl domain ResIII PF04851.15 CBZ36877.1 - 6.3e-07 29.5 0.0 1.8e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ36877.1 - 1.6e-06 28.4 0.0 6.1e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 CBZ36877.1 - 0.025 13.6 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Cyclase PF04199.13 CBZ36878.1 - 1.7e-08 34.8 0.1 4.8e-08 33.3 0.1 1.9 1 1 0 1 1 1 1 Putative cyclase Extensin_2 PF04554.13 CBZ36880.1 - 0.011 15.8 8.4 0.011 15.8 8.4 4.1 3 1 0 4 4 4 0 Extensin-like region TF_Zn_Ribbon PF08271.12 CBZ36880.1 - 0.23 11.0 0.2 0.42 10.2 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding MnmE_helical PF12631.7 CBZ36880.1 - 0.44 10.7 1.7 0.75 9.9 1.7 1.3 1 0 0 1 1 1 0 MnmE helical domain Chloroa_b-bind PF00504.21 CBZ36881.1 - 0.13 12.8 1.0 0.14 12.6 0.5 1.4 1 1 0 1 1 1 0 Chlorophyll A-B binding protein PI3_PI4_kinase PF00454.27 CBZ36883.1 - 1.2e-44 153.0 0.2 2.1e-44 152.2 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CBZ36883.1 - 2e-10 40.3 0.7 2e-10 40.3 0.7 2.6 3 0 0 3 3 3 1 FATC domain FAT PF02259.23 CBZ36883.1 - 3.9e-07 29.6 4.4 5.2e-06 25.9 0.3 3.3 2 1 0 2 2 2 1 FAT domain DUF4395 PF14340.6 CBZ36883.1 - 0.075 13.4 0.8 0.29 11.4 0.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) UME PF08064.13 CBZ36883.1 - 0.12 12.3 0.0 0.55 10.2 0.0 2.2 1 0 0 1 1 1 0 UME (NUC010) domain MIP-T3 PF10243.9 CBZ36884.1 - 5e-27 94.1 0.1 9.2e-27 93.3 0.1 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain Fib_alpha PF08702.10 CBZ36884.1 - 0.027 14.7 1.6 0.57 10.4 0.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CEP209_CC5 PF16574.5 CBZ36884.1 - 0.084 13.0 2.3 5.7 7.1 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 rRNA_processing PF08524.11 CBZ36886.1 - 3.6e-10 40.0 36.1 1.3e-08 35.0 36.1 2.1 1 1 0 1 1 1 1 rRNA processing DUF4407 PF14362.6 CBZ36886.1 - 0.47 9.8 19.4 0.58 9.5 19.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_M41 PF01434.18 CBZ36888.1 - 1.3e-46 158.9 0.2 1.9e-46 158.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBZ36888.1 - 3.9e-41 140.6 0.0 7.4e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ36888.1 - 6.8e-05 23.3 0.1 0.0009 19.7 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ36888.1 - 0.002 18.4 0.1 0.031 14.5 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ36888.1 - 0.0044 17.0 0.0 0.021 14.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBZ36888.1 - 0.0093 15.7 0.0 0.028 14.2 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBZ36888.1 - 0.011 15.0 0.1 0.022 14.0 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain Sigma54_activat PF00158.26 CBZ36888.1 - 0.036 13.8 0.0 0.17 11.6 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CBZ36888.1 - 0.037 13.3 0.0 0.086 12.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 CBZ36888.1 - 0.076 12.7 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 CBZ36888.1 - 0.083 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 CBZ36888.1 - 0.12 12.1 0.1 0.78 9.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 CBZ36888.1 - 0.15 12.1 0.3 1.6 8.8 0.2 2.5 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 CBZ36888.1 - 0.17 11.8 0.0 0.67 9.8 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 CBZ36888.1 - 0.19 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain YqaJ PF09588.10 CBZ36890.1 - 1.4e-62 210.3 0.0 5.5e-62 208.3 0.0 1.9 1 1 0 1 1 1 1 YqaJ-like viral recombinase domain NUDIX PF00293.28 CBZ36892.1 - 2.3e-12 47.1 0.4 3.4e-12 46.5 0.4 1.3 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 CBZ36893.1 - 2e-06 27.9 0.0 3.8e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain PSP1 PF04468.12 CBZ36894.1 - 7.6e-23 80.6 1.3 1.3e-22 79.9 1.3 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region eIF3_p135 PF12807.7 CBZ36895.1 - 1e-11 45.2 0.0 1.8e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 CLU PF13236.6 CBZ36895.1 - 1.7e-07 31.3 0.0 5.3e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Clustered mitochondria zf-RING_4 PF14570.6 CBZ36895.1 - 0.18 11.7 4.9 0.52 10.1 4.9 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ArfGap PF01412.18 CBZ36896.1 - 7e-41 139.0 0.1 1.1e-40 138.3 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PMI_typeI PF01238.21 CBZ36897.1 - 2.2e-90 303.5 0.0 2.7e-90 303.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF2312 PF10073.9 CBZ36897.1 - 0.2 11.4 0.3 0.44 10.2 0.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) PIN_11 PF18479.1 CBZ36900.1 - 0.032 14.4 0.2 0.38 10.9 0.2 2.3 1 1 0 1 1 1 0 PIN like domain PDZ_4 PF17816.1 CBZ36903.1 - 0.14 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 PDZ domain NAD_synthase PF02540.17 CBZ36906.1 - 5.6e-32 110.8 0.0 7.7e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 CBZ36906.1 - 0.057 13.1 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase PAPS_reduct PF01507.19 CBZ36906.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF2184 PF09950.9 CBZ36907.1 - 0.048 13.0 0.1 5.9 6.2 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2184) PP2C PF00481.21 CBZ36908.1 - 3.8e-68 229.9 0.0 6.5e-68 229.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoU_methylase PF00588.19 CBZ36910.1 - 9.9e-10 38.7 0.0 0.012 15.8 0.0 3.6 4 0 0 4 4 4 3 SpoU rRNA Methylase family cwf21 PF08312.12 CBZ36910.1 - 0.15 12.2 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 cwf21 domain DNA_pol_E_B PF04042.16 CBZ36911.1 - 3.4e-13 49.4 0.2 5.5e-11 42.2 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Coatomer_E PF04733.14 CBZ36912.1 - 8.2e-30 104.2 6.3 7.3e-29 101.1 6.3 1.9 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 CBZ36912.1 - 1.4e-05 24.8 4.8 0.34 11.1 0.0 5.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ36912.1 - 0.00036 21.1 12.9 0.37 11.7 1.0 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ36912.1 - 0.0024 18.1 9.2 0.027 14.8 3.2 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ36912.1 - 0.0047 16.7 3.5 0.54 10.2 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ36912.1 - 0.0061 17.2 19.0 0.0069 17.0 3.8 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ36912.1 - 0.0074 16.4 4.5 0.26 11.6 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ36912.1 - 0.01 15.7 4.8 3.3 7.7 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ36912.1 - 0.024 15.2 12.3 0.61 10.6 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ36912.1 - 0.045 14.4 2.0 0.41 11.4 0.3 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ36912.1 - 0.098 12.9 3.9 3.3 8.0 0.3 3.7 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CBZ36912.1 - 0.15 12.1 0.3 5.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat CD225 PF04505.12 CBZ36912.1 - 0.86 9.8 0.0 0.86 9.8 0.0 3.2 4 0 0 4 4 4 0 Interferon-induced transmembrane protein TPR_7 PF13176.6 CBZ36912.1 - 1 9.6 3.2 21 5.4 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat WW PF00397.26 CBZ36913.1 - 1.6e-12 47.3 1.2 2.5e-12 46.6 1.2 1.3 1 0 0 1 1 1 1 WW domain zf-CCCH PF00642.24 CBZ36913.1 - 1.2e-05 25.1 1.9 1.2e-05 25.0 0.7 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ36913.1 - 0.00012 22.0 1.3 0.00028 20.8 1.3 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBZ36913.1 - 0.0019 18.0 0.7 0.0038 17.0 0.7 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CBZ36913.1 - 0.0048 17.6 0.5 0.0062 17.2 0.5 1.2 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 CBZ36913.1 - 0.048 14.2 0.5 0.13 12.8 0.5 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Glyco_hyd_101C PF17451.2 CBZ36913.1 - 0.13 12.6 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain PUF PF00806.19 CBZ36914.1 - 7.2e-23 78.9 0.0 0.021 14.5 0.0 9.1 10 0 0 10 10 10 7 Pumilio-family RNA binding repeat UTP15_C PF09384.10 CBZ36914.1 - 0.067 12.9 7.0 0.73 9.5 0.1 3.5 4 0 0 4 4 4 0 UTP15 C terminal DAZAP2 PF11029.8 CBZ36916.1 - 0.088 13.7 2.6 0.27 12.2 0.3 2.6 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) zf-RING_12 PF17976.1 CBZ36916.1 - 0.089 13.1 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2726 PF10881.8 CBZ36917.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) MRI PF15325.6 CBZ36919.1 - 4.4 8.5 8.4 1.8 9.7 5.8 1.7 2 0 0 2 2 2 0 Modulator of retrovirus infection Pkinase PF00069.25 CBZ36921.1 - 1e-45 156.2 0.0 2.9e-44 151.4 0.0 2.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ36921.1 - 1.9e-30 106.0 0.0 1e-29 103.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBZ36921.1 - 7.4e-07 29.6 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 CBZ36921.1 - 0.0016 17.8 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH_9 PF15410.6 CBZ36921.1 - 0.0038 17.6 0.0 0.0079 16.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain Sod_Fe_C PF02777.18 CBZ36922.1 - 2.7e-38 130.2 0.0 4.1e-38 129.6 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBZ36922.1 - 2.1e-18 66.6 0.2 4.6e-18 65.5 0.1 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 CBZ36923.1 - 2.5e-38 130.3 0.0 3.9e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBZ36923.1 - 4.3e-18 65.6 0.6 8.6e-18 64.6 0.1 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Ras PF00071.22 CBZ36924.1 - 1.3e-35 122.3 0.0 1.7e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ36924.1 - 6.4e-32 110.3 0.0 9.7e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ36924.1 - 3.1e-10 39.8 0.0 4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CBZ36924.1 - 8.7e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CBZ36924.1 - 1.3e-05 24.7 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CBZ36924.1 - 2.4e-05 24.0 0.0 0.0017 17.9 0.0 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CBZ36924.1 - 4.1e-05 23.6 0.0 6.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 CBZ36924.1 - 0.00017 21.0 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein MMR_HSR1_Xtn PF16897.5 CBZ36924.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 CBZ36924.1 - 0.0022 17.8 0.0 0.0036 17.1 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CBZ36924.1 - 0.0024 17.8 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CBZ36924.1 - 0.12 12.8 0.0 0.15 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Cpn60_TCP1 PF00118.24 CBZ36925.1 - 1.1e-82 278.3 4.9 2.2e-82 277.2 4.9 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_efflux PF01545.21 CBZ36927.1 - 7e-07 29.2 1.9 1.2e-06 28.4 1.9 1.4 1 0 0 1 1 1 1 Cation efflux family CBFD_NFYB_HMF PF00808.23 CBZ36928.1 - 0.0013 19.0 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DNA_pol_A_exo1 PF01612.20 CBZ36929.1 - 8.6e-11 41.9 0.0 3e-10 40.1 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease DUF1663 PF07909.11 CBZ36932.1 - 0.13 11.0 9.3 0.012 14.4 4.1 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1663) DUF647 PF04884.14 CBZ36933.1 - 1.4e-35 123.1 7.9 2.3e-35 122.3 7.9 1.4 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis WDCP PF15390.6 CBZ36934.1 - 0.15 10.4 4.9 0.32 9.3 4.9 1.5 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Phlebovirus_NSM PF07246.11 CBZ36934.1 - 3.3 7.0 6.0 2 7.7 4.2 1.5 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DnaJ_C PF01556.18 CBZ36935.1 - 1.7e-34 119.0 0.0 2.3e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ36935.1 - 6.8e-16 58.2 0.5 1.3e-15 57.2 0.5 1.5 1 1 0 1 1 1 1 DnaJ domain Qn_am_d_aII PF14930.6 CBZ36935.1 - 0.048 14.0 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Acyltransferase PF01553.21 CBZ36937.1 - 2.2e-15 56.4 0.2 7e-15 54.8 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase Lipase_GDSL_3 PF14606.6 CBZ36937.1 - 0.026 14.7 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Ribo_biogen_C PF04034.13 CBZ36939.1 - 2.5e-49 166.2 0.0 3.3e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CBZ36939.1 - 1.2e-11 44.2 0.0 2.4e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Med3 PF11593.8 CBZ36940.1 - 9.1 5.3 14.2 11 5.1 14.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4200 PF13863.6 CBZ36941.1 - 2.4e-21 76.3 14.7 2.4e-21 76.3 14.7 4.3 4 0 0 4 4 4 2 Domain of unknown function (DUF4200) DUF2730 PF10805.8 CBZ36941.1 - 0.19 11.9 10.5 2 8.5 0.5 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) NuA4 PF09340.10 CBZ36941.1 - 3.3 7.6 7.5 0.26 11.2 0.3 2.8 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 DUF16 PF01519.16 CBZ36941.1 - 6.4 7.3 15.3 17 6.0 4.1 4.0 3 1 0 3 3 3 0 Protein of unknown function DUF16 Endosulfine PF04667.17 CBZ36942.1 - 0.00036 20.6 7.3 0.00056 20.0 7.3 1.5 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF2981 PF11200.8 CBZ36942.1 - 0.12 12.1 0.5 0.12 12.1 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Suf PF05843.14 CBZ36942.1 - 0.6 10.0 7.3 0.62 10.0 7.3 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 CBZ36942.1 - 0.85 9.5 11.9 0.86 9.5 11.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CBZ36942.1 - 3 7.4 15.9 3.5 7.2 15.9 1.1 1 0 0 1 1 1 0 Spt20 family FCP1_C PF09309.10 CBZ36942.1 - 9.9 6.0 11.3 13 5.6 11.3 1.1 1 0 0 1 1 1 0 FCP1, C-terminal DUF3456 PF11938.8 CBZ36943.1 - 2.1e-30 106.3 0.8 1.2e-29 103.8 0.1 1.9 2 0 0 2 2 2 1 TLR4 regulator and MIR-interacting MSAP PEHE PF15275.6 CBZ36943.1 - 0.062 13.9 0.9 0.062 13.9 0.9 1.8 2 0 0 2 2 2 0 PEHE domain MIR PF02815.19 CBZ36944.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 MIR domain EMP24_GP25L PF01105.24 CBZ36945.1 - 2.1e-31 109.3 0.0 2.4e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ras PF00071.22 CBZ36946.1 - 1e-60 204.0 0.0 1.2e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ36946.1 - 5e-33 113.9 0.0 8.3e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ36946.1 - 1.8e-12 47.1 0.0 2.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBZ36946.1 - 0.00023 21.2 0.0 0.00055 20.0 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ36946.1 - 0.00032 20.7 0.0 0.2 11.5 0.0 2.6 2 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 CBZ36946.1 - 0.00036 20.1 0.0 0.0015 18.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CBZ36946.1 - 0.00046 19.6 0.0 0.00069 19.0 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CBZ36946.1 - 0.021 15.1 0.1 0.074 13.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.9 CBZ36946.1 - 0.038 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CBZ36946.1 - 0.098 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CBZ36946.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ36946.1 - 0.14 12.5 0.1 0.24 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain TetR_C_16 PF17920.1 CBZ36946.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF5617 PF18493.1 CBZ36948.1 - 0.0069 16.5 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5617) ABC_tran PF00005.27 CBZ36949.1 - 1.8e-17 64.2 0.0 3.2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBZ36949.1 - 9e-09 35.5 0.9 6.7e-05 22.8 0.3 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 CBZ36949.1 - 1.4e-07 31.5 7.6 2.7e-07 30.5 7.6 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CBZ36949.1 - 5.3e-07 29.3 0.0 4.6e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CBZ36949.1 - 0.00071 19.5 0.1 0.0023 17.9 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CBZ36949.1 - 0.0014 19.1 0.1 0.0052 17.2 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ36949.1 - 0.0029 17.9 2.9 0.028 14.7 2.1 2.7 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CBZ36949.1 - 0.012 16.1 0.2 0.25 11.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CBZ36949.1 - 0.015 15.8 0.0 0.024 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CBZ36949.1 - 0.015 15.0 0.0 0.8 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 CBZ36949.1 - 0.038 13.9 0.1 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Adeno_IVa2 PF02456.15 CBZ36949.1 - 0.044 12.6 0.1 0.076 11.8 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_29 PF13555.6 CBZ36949.1 - 0.059 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CBZ36949.1 - 0.072 13.5 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase SbcCD_C PF13558.6 CBZ36949.1 - 0.11 12.7 0.1 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 CBZ36949.1 - 0.12 11.9 0.4 0.39 10.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBZ36949.1 - 0.26 11.2 0.1 0.53 10.2 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CTP_transf_like PF01467.26 CBZ36950.1 - 2.3e-09 37.6 0.0 4.9e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 CBZ36950.1 - 0.018 14.9 0.1 0.14 12.0 0.1 2.1 2 0 0 2 2 2 0 FAD synthetase dCMP_cyt_deam_1 PF00383.23 CBZ36951.1 - 3.1e-07 30.2 0.0 9.8e-07 28.6 0.0 1.9 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CBZ36951.1 - 4.9e-06 26.4 0.0 9.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 CBZ36951.1 - 0.0014 18.7 0.0 0.0051 16.9 0.0 2.0 2 0 0 2 2 2 1 Bd3614-like deaminase Cons_hypoth95 PF03602.15 CBZ36952.1 - 0.024 14.3 0.0 0.074 12.7 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 KLRAQ PF10205.9 CBZ36953.1 - 0.23 11.7 0.1 0.23 11.7 0.1 4.2 3 1 1 4 4 4 0 Predicted coiled-coil domain-containing protein TMPIT PF07851.13 CBZ36953.1 - 0.28 10.4 2.7 0.66 9.2 2.7 1.5 1 0 0 1 1 1 0 TMPIT-like protein MAD PF05557.13 CBZ36953.1 - 1.6 7.0 20.3 0.23 9.8 15.0 1.9 2 0 0 2 2 2 0 Mitotic checkpoint protein Fungal_TACC PF12709.7 CBZ36953.1 - 2.8 8.4 11.7 19 5.8 0.1 4.0 3 1 2 5 5 5 0 Fungal Transforming acidic coiled-coil (TACC) proteins baeRF_family7 PF18849.1 CBZ36954.1 - 0.2 11.8 0.0 0.54 10.4 0.0 1.7 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 RRM_1 PF00076.22 CBZ36956.1 - 2.6e-07 30.3 0.0 4.8e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 CBZ36956.1 - 0.00014 22.2 0.1 0.00014 22.2 0.1 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 DUF3292 PF11696.8 CBZ36956.1 - 6 5.1 7.8 8.7 4.6 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Importin_rep_4 PF18808.1 CBZ36958.1 - 1.3e-17 63.8 2.0 3e-13 49.9 0.0 4.0 3 0 0 3 3 3 2 Importin repeat HEAT_EZ PF13513.6 CBZ36958.1 - 1.5e-09 38.2 3.9 0.48 11.0 0.0 6.3 5 0 0 5 5 5 3 HEAT-like repeat HEAT PF02985.22 CBZ36958.1 - 6.2e-08 32.2 9.9 0.35 11.2 0.5 6.9 6 0 0 6 6 6 3 HEAT repeat Cnd1 PF12717.7 CBZ36958.1 - 4.4e-06 26.8 0.6 0.00025 21.1 0.1 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ36958.1 - 1.9e-05 24.9 0.6 0.0045 17.4 0.1 4.5 4 1 2 6 6 6 2 HEAT repeats RTP1_C1 PF10363.9 CBZ36958.1 - 0.003 17.7 3.0 0.3 11.3 0.0 4.3 4 1 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 CBZ36958.1 - 0.017 15.0 0.2 0.92 9.4 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) DUF4487 PF14868.6 CBZ36958.1 - 0.087 11.6 0.8 1.7 7.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4487) Synaptobrevin PF00957.21 CBZ36960.1 - 1.1e-08 34.7 4.0 2.4e-08 33.6 4.0 1.4 1 0 0 1 1 1 1 Synaptobrevin CSN8_PSD8_EIF3K PF10075.9 CBZ36962.1 - 7.6e-15 55.1 0.1 1.4e-14 54.3 0.0 1.4 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 CBZ36962.1 - 0.0024 18.3 0.0 0.0034 17.9 0.0 1.3 1 0 0 1 1 1 1 PCI domain FPL PF09758.9 CBZ36962.1 - 0.081 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein DUF4551 PF15087.6 CBZ36963.1 - 3.8 6.2 7.9 5.6 5.7 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) GTP_EFTU PF00009.27 CBZ36964.1 - 7.9e-27 94.1 0.0 2.3e-25 89.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CBZ36964.1 - 6e-17 61.5 0.0 1.5e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CBZ36964.1 - 1.4e-08 34.7 0.0 2.8e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CBZ36964.1 - 2.1e-06 27.8 0.0 3.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.18 CBZ36964.1 - 3.1e-06 27.0 0.0 7.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV Dynamin_N PF00350.23 CBZ36964.1 - 8.2e-05 22.7 0.1 0.08 13.0 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Septin PF00735.18 CBZ36964.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 CBZ36964.1 - 0.0025 17.3 0.0 0.004 16.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 CBZ36964.1 - 0.0047 17.1 0.0 0.0097 16.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 CBZ36964.1 - 0.16 11.4 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein EFTUD2 PF16004.5 CBZ36964.1 - 0.45 11.1 3.0 24 5.5 3.0 2.3 1 1 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Complex1_LYR PF05347.15 CBZ36965.1 - 3.4e-12 46.2 0.8 7.2e-12 45.2 0.8 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 CBZ36965.1 - 0.002 18.7 0.3 0.004 17.7 0.3 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DnaB_bind PF10410.9 CBZ36965.1 - 3.2 8.0 8.2 0.78 10.0 1.0 3.1 3 1 1 4 4 4 0 DnaB-helicase binding domain of primase Spc7 PF08317.11 CBZ36966.1 - 4e-05 22.7 17.9 4e-05 22.7 17.9 2.4 3 0 0 3 3 3 1 Spc7 kinetochore protein Filament PF00038.21 CBZ36966.1 - 0.0035 17.0 16.7 0.0035 17.0 16.7 2.8 2 1 1 3 3 3 1 Intermediate filament protein Rootletin PF15035.6 CBZ36966.1 - 0.0095 16.0 15.1 0.0095 16.0 15.1 2.5 2 0 0 2 2 2 1 Ciliary rootlet component, centrosome cohesion LMBR1 PF04791.16 CBZ36966.1 - 0.81 8.5 11.6 1.2 7.9 11.6 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4201 PF13870.6 CBZ36966.1 - 8.9 6.0 31.3 0.066 13.0 8.4 4.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) DEAD PF00270.29 CBZ36967.1 - 4.7e-41 140.5 0.0 9.4e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ36967.1 - 9.1e-24 83.9 0.0 2.1e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBZ36967.1 - 3.5e-14 52.7 0.2 7.7e-14 51.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBZ36967.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Formyl_trans_N PF00551.19 CBZ36968.1 - 3.9e-16 59.3 0.0 8.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase CoA_binding_2 PF13380.6 CBZ36968.1 - 0.015 15.8 0.1 7.5 7.1 0.0 2.6 2 0 0 2 2 2 0 CoA binding domain Cas_Cas02710 PF09670.10 CBZ36969.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) CS PF04969.16 CBZ36970.1 - 0.0094 17.0 0.0 0.0094 17.0 0.0 1.7 2 0 0 2 2 2 1 CS domain PAP2 PF01569.21 CBZ36973.1 - 2.6e-16 59.6 2.5 2.6e-16 59.6 2.5 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CBZ36973.1 - 0.0015 18.2 2.9 0.0015 18.2 2.9 3.0 3 0 0 3 3 3 2 PAP2 superfamily TraU PF06834.11 CBZ36973.1 - 0.058 12.7 0.6 0.11 11.8 0.6 1.4 1 0 0 1 1 1 0 TraU protein ERG4_ERG24 PF01222.17 CBZ36976.1 - 3.4e-124 414.9 4.1 3.9e-124 414.7 4.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CBZ36976.1 - 2e-08 34.0 0.7 1e-07 31.8 0.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 CBZ36976.1 - 0.00019 21.8 0.1 0.0008 19.8 0.0 2.2 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 CBZ36976.1 - 0.0049 17.3 0.0 0.0049 17.3 0.0 3.1 4 0 0 4 4 4 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family EamA PF00892.20 CBZ36977.1 - 0.0016 18.6 8.7 0.0032 17.6 8.7 1.5 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 CBZ36977.1 - 0.034 14.2 0.9 0.043 13.8 0.9 1.2 1 0 0 1 1 1 0 Putative transmembrane family 234 MIP PF00230.20 CBZ36979.1 - 3.7e-29 102.1 15.8 5.5e-29 101.5 15.8 1.2 1 0 0 1 1 1 1 Major intrinsic protein Tub_N PF16322.5 CBZ36979.1 - 0.067 13.6 4.9 0.056 13.8 3.0 1.7 2 0 0 2 2 2 0 Tubby N-terminal Podoplanin PF05808.11 CBZ36979.1 - 0.29 11.2 3.0 1 9.4 3.0 2.0 1 0 0 1 1 1 0 Podoplanin MIP PF00230.20 CBZ36980.1 - 1.2e-34 120.0 17.7 1.4e-34 119.8 17.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein Nsp1_C PF05064.13 CBZ36982.1 - 5.7e-09 35.8 0.4 9.4e-09 35.1 0.4 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Cep57_MT_bd PF06657.13 CBZ36982.1 - 0.012 16.0 2.3 0.059 13.8 0.5 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 T3SSipB PF16535.5 CBZ36982.1 - 0.019 15.5 4.0 0.019 15.5 4.0 1.7 2 0 0 2 2 2 0 Type III cell invasion protein SipB Spc7 PF08317.11 CBZ36982.1 - 0.021 13.7 3.8 0.03 13.2 3.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PIN_8 PF18476.1 CBZ36982.1 - 0.03 14.2 0.5 0.044 13.6 0.5 1.1 1 0 0 1 1 1 0 PIN like domain Exonuc_VII_L PF02601.15 CBZ36982.1 - 0.075 12.6 2.6 0.13 11.8 2.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mut7-C PF01927.16 CBZ36982.1 - 0.078 13.1 0.9 0.13 12.4 0.9 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain Tropomyosin_1 PF12718.7 CBZ36982.1 - 0.091 12.9 1.9 0.14 12.3 1.9 1.2 1 0 0 1 1 1 0 Tropomyosin like ABC_tran_CTD PF16326.5 CBZ36982.1 - 0.3 11.4 3.1 0.71 10.2 3.1 1.7 1 0 0 1 1 1 0 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 CBZ36982.1 - 2.8 7.9 5.2 3.8 7.5 1.2 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NAD_binding_1 PF00175.21 CBZ36983.1 - 1.3e-18 67.7 0.0 3.1e-16 60.0 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CBZ36983.1 - 1.7e-12 47.6 0.0 2.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CBZ36983.1 - 0.001 19.2 0.0 0.0025 18.0 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain TPR_12 PF13424.6 CBZ36985.1 - 6.5e-07 29.6 3.9 6.5e-07 29.6 3.9 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 CBZ36985.1 - 0.0016 18.4 2.1 0.014 15.4 0.6 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 CBZ36985.1 - 0.071 13.0 8.7 6.1 6.8 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ36985.1 - 0.2 11.8 14.6 1.4 9.2 0.4 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3292 PF11696.8 CBZ36985.1 - 0.57 8.5 12.3 0.0056 15.1 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) TPR_10 PF13374.6 CBZ36985.1 - 1.6 8.7 8.1 2.9 7.9 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ36985.1 - 4.8 7.4 12.0 1.3 9.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Methyltr_RsmB-F PF01189.17 CBZ36987.1 - 1.8e-29 102.9 0.0 2.9e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F MTS PF05175.14 CBZ36987.1 - 0.087 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain MelC1 PF06236.11 CBZ36987.1 - 5.5 7.1 6.2 1.7 8.8 0.1 2.6 3 0 0 3 3 3 0 Tyrosinase co-factor MelC1 NUDIX PF00293.28 CBZ36988.1 - 0.0028 17.7 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain PAP_assoc PF03828.19 CBZ36989.1 - 7.2e-09 35.7 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CBZ36989.1 - 0.0042 17.4 0.0 0.0083 16.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBZ36989.1 - 0.013 15.6 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase ubiquitin PF00240.23 CBZ36991.1 - 0.034 13.9 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family TPR_14 PF13428.6 CBZ36992.1 - 2.7e-07 30.8 45.2 0.26 12.2 0.2 11.0 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ36992.1 - 0.00018 21.6 0.4 3.9 8.1 0.1 4.8 3 0 0 3 3 3 1 Tetratricopeptide repeat PRP1_N PF06424.12 CBZ36992.1 - 0.0011 19.4 2.4 0.0025 18.2 2.4 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_2 PF07719.17 CBZ36992.1 - 0.0047 16.9 1.7 0.0047 16.9 1.7 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ36992.1 - 0.015 15.5 1.8 0.13 12.5 0.4 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CBZ36992.1 - 0.021 14.7 1.3 0.28 11.1 1.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ACTH_assoc PF16102.5 CBZ36992.1 - 0.068 14.0 2.7 0.22 12.4 1.3 2.8 2 0 0 2 2 2 0 ACTH-associated domain CAMSAP_CC1 PF17095.5 CBZ36992.1 - 0.095 12.6 0.8 0.36 10.7 0.8 2.0 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin TPR_12 PF13424.6 CBZ36992.1 - 0.18 12.1 17.5 0.21 11.9 1.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat cNMP_binding PF00027.29 CBZ36996.1 - 8.4e-12 45.0 0.4 0.00013 21.9 0.0 5.6 5 1 0 5 5 5 3 Cyclic nucleotide-binding domain HD PF01966.22 CBZ36997.1 - 2.1e-07 31.2 0.0 7.1e-07 29.5 0.0 2.1 1 0 0 1 1 1 1 HD domain A_deaminase PF00962.22 CBZ36998.1 - 4.5e-92 308.9 0.1 5.1e-68 229.8 0.0 2.5 3 0 0 3 3 3 2 Adenosine/AMP deaminase DUF4603 PF15376.6 CBZ36998.1 - 0.056 10.9 0.0 0.083 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CHCH PF06747.13 CBZ37002.1 - 0.021 15.0 3.3 0.033 14.3 3.3 1.4 1 0 0 1 1 1 0 CHCH domain PHD_3 PF13922.6 CBZ37004.1 - 1.2 9.6 10.6 0.081 13.3 0.5 3.9 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx Complex1_LYR PF05347.15 CBZ37005.1 - 6.5e-05 22.9 0.7 0.00017 21.6 0.7 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Sod_Fe_C PF02777.18 CBZ37006.1 - 1.8e-31 108.3 1.6 2.4e-31 107.9 0.5 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CBZ37006.1 - 7.9e-20 71.1 0.3 2.1e-19 69.8 0.3 1.8 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cys_Met_Meta_PP PF01053.20 CBZ37007.1 - 2.8e-89 299.3 0.0 3.2e-89 299.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CBZ37007.1 - 1.5e-06 27.6 0.1 2.3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CBZ37007.1 - 0.01 15.1 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CBZ37007.1 - 0.025 13.6 0.0 0.037 13.0 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBZ37007.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase HyaE PF07449.11 CBZ37007.1 - 0.17 11.8 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE SpoU_methylase PF00588.19 CBZ37008.1 - 1e-24 87.3 0.1 6.7e-23 81.4 0.0 3.8 4 0 0 4 4 4 1 SpoU rRNA Methylase family Aa_trans PF01490.18 CBZ37009.1 - 6.6e-52 176.6 29.7 8.2e-52 176.3 29.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ37009.1 - 3.7e-10 39.4 11.0 5e-10 39.0 10.0 1.7 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.6 CBZ37009.1 - 2.5 6.8 36.0 0.0023 16.8 21.5 2.1 1 1 1 2 2 2 0 Amino acid permease FTCD_C PF04961.12 CBZ37010.1 - 0.022 14.5 14.5 0.025 14.4 4.3 3.6 3 0 0 3 3 3 0 Formiminotransferase-cyclodeaminase VASt PF16016.5 CBZ37011.1 - 4.4e-09 36.9 0.0 8.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain Ribosomal_L27e PF01777.18 CBZ37012.1 - 8.2e-25 87.0 1.4 1.2e-24 86.5 1.4 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CBZ37012.1 - 3.5e-05 23.6 0.4 3.5e-05 23.6 0.4 1.7 2 0 0 2 2 2 1 KOW motif DUF3446 PF11928.8 CBZ37013.1 - 1.3 9.4 7.3 0.89 9.9 4.0 2.5 1 1 1 2 2 2 0 Early growth response N-terminal domain Ribosomal_L27e PF01777.18 CBZ37014.1 - 8.2e-25 87.0 1.4 1.2e-24 86.5 1.4 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CBZ37014.1 - 3.5e-05 23.6 0.4 3.5e-05 23.6 0.4 1.7 2 0 0 2 2 2 1 KOW motif Sybindin PF04099.12 CBZ37015.1 - 5.2e-22 78.3 0.0 6.1e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CBZ37015.1 - 1.3e-06 28.6 0.0 1.3e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region COPI_C PF06957.11 CBZ37016.1 - 0.58 8.9 0.0 0.58 8.9 0.0 1.7 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus SelP_N PF04592.14 CBZ37016.1 - 1.7 8.0 13.6 3.3 7.1 13.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Rhodanese PF00581.20 CBZ37017.1 - 1.4e-07 32.0 0.0 1.8e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF952 PF06108.12 CBZ37017.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF952) Sec7_N PF12783.7 CBZ37018.1 - 1.7e-19 70.3 0.2 6.1e-19 68.5 0.2 1.9 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.20 CBZ37018.1 - 3.2e-18 66.1 0.0 4.8e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain DUF4140 PF13600.6 CBZ37019.1 - 0.0026 18.2 5.4 0.018 15.5 1.3 2.6 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 CBZ37019.1 - 0.6 9.4 5.9 4.2 6.6 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) RNase_T PF00929.24 CBZ37022.1 - 1.8e-12 48.1 0.0 2.7e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CBZ37022.1 - 0.081 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 3'-5' exonuclease RRM_1 PF00076.22 CBZ37024.1 - 1.7e-20 72.6 0.1 8.7e-07 28.7 0.0 4.0 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CBZ37024.1 - 0.013 15.4 0.1 0.082 12.7 0.0 2.3 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RPN7 PF10602.9 CBZ37025.1 - 1.5e-48 164.8 0.0 2.7e-48 164.0 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CBZ37025.1 - 1.6e-15 57.5 0.3 4.2e-15 56.1 0.0 1.9 3 0 0 3 3 3 1 PCI domain IFT46_B_C PF12317.8 CBZ37025.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Secretin_N_2 PF07655.13 CBZ37026.1 - 1.1 9.9 3.8 0.39 11.3 0.2 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Prefoldin PF02996.17 CBZ37027.1 - 2.6e-09 37.0 0.2 4.7e-09 36.2 0.2 1.5 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 CBZ37027.1 - 6.9e-06 26.0 1.6 0.0056 16.7 0.2 2.3 2 0 0 2 2 2 2 Prefoldin subunit TPR_2 PF07719.17 CBZ37028.1 - 4.1e-09 35.9 20.5 0.038 14.1 0.2 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ37028.1 - 1.9e-08 33.8 17.5 0.15 11.9 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ37028.1 - 8e-08 32.8 0.6 8e-08 32.8 0.6 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ37028.1 - 2.3e-06 28.0 12.6 0.00011 22.6 0.8 5.1 4 2 0 4 4 4 2 Tetratricopeptide repeat CS PF04969.16 CBZ37028.1 - 1.8e-05 25.7 0.2 4.3e-05 24.5 0.1 1.7 2 0 0 2 2 1 1 CS domain TPR_12 PF13424.6 CBZ37028.1 - 0.0021 18.3 19.9 0.39 11.0 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ37028.1 - 0.012 15.7 7.5 4.5 7.4 0.1 4.3 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CBZ37028.1 - 0.024 14.9 10.3 2 8.7 0.7 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CBZ37028.1 - 0.029 15.0 1.3 0.81 10.5 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ37028.1 - 0.064 14.1 25.3 1.3 10.0 0.1 7.2 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ37028.1 - 0.2 11.6 8.5 2.6 8.0 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPPII_N PF12583.8 CBZ37028.1 - 1.3 9.6 10.1 1.1 9.8 0.1 2.9 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal TPR_8 PF13181.6 CBZ37028.1 - 2.6 8.5 12.6 12 6.4 0.1 4.8 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ37028.1 - 6.7 7.0 18.0 43 4.5 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat FYVE PF01363.21 CBZ37029.1 - 0.0066 16.6 13.5 0.018 15.2 13.5 1.7 1 0 0 1 1 1 1 FYVE zinc finger CTP_transf_1 PF01148.20 CBZ37030.1 - 3.6e-32 112.2 11.3 2.8e-30 106.0 0.3 3.6 4 0 0 4 4 4 2 Cytidylyltransferase family DUF92 PF01940.16 CBZ37030.1 - 0.31 10.4 6.5 2.1 7.7 0.4 2.7 3 0 0 3 3 3 0 Integral membrane protein DUF92 DUF778 PF05608.12 CBZ37031.1 - 6.5e-72 241.9 0.0 6.5e-72 241.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF778) SNAP PF14938.6 CBZ37033.1 - 1.1e-54 185.8 20.1 1.3e-54 185.6 20.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 CBZ37033.1 - 0.0002 21.9 16.6 1.4 10.0 0.3 5.5 3 1 2 5 5 5 3 Tetratricopeptide repeat Foie-gras_1 PF11817.8 CBZ37033.1 - 0.0034 17.0 5.7 0.0053 16.4 5.7 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_12 PF13424.6 CBZ37033.1 - 0.016 15.5 9.4 3.1 8.1 0.1 4.0 1 1 1 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CBZ37033.1 - 0.04 14.4 7.7 0.57 10.6 0.1 2.8 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_19 PF14559.6 CBZ37033.1 - 0.34 11.5 14.0 1 9.9 0.7 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat UCH PF00443.29 CBZ37035.1 - 2.4e-50 171.4 0.0 4.2e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ37035.1 - 1.1e-13 51.4 2.7 2.6e-08 33.9 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase FG-GAP PF01839.23 CBZ37036.1 - 0.0016 18.5 0.1 0.0051 16.9 0.1 1.9 1 0 0 1 1 1 1 FG-GAP repeat VCBS PF13517.6 CBZ37036.1 - 0.06 13.9 0.4 0.28 11.8 0.0 2.4 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella PQQ PF01011.21 CBZ37036.1 - 0.63 10.1 2.0 3.9 7.6 0.1 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat TTL PF03133.15 CBZ37037.1 - 9.6e-71 238.3 0.0 2.6e-58 197.5 0.0 2.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ37037.1 - 7.4e-08 31.9 0.0 0.00079 18.7 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp DUF1738 PF08401.11 CBZ37038.1 - 0.0022 18.1 0.0 1.4 9.0 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF1738) NigD_C PF17415.2 CBZ37038.1 - 0.022 14.8 0.0 0.87 9.7 0.0 2.4 2 0 0 2 2 2 0 NigD-like C-terminal beta sandwich domain NDK PF00334.19 CBZ37039.1 - 7.3e-57 191.1 0.0 8.4e-57 191.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MCM PF00493.23 CBZ37040.1 - 1.2e-97 325.4 0.0 1.8e-97 324.9 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ37040.1 - 2.7e-27 95.1 1.7 5.5e-27 94.1 1.7 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ37040.1 - 5.3e-21 74.8 0.1 1.4e-20 73.4 0.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBZ37040.1 - 2.5e-07 31.2 0.1 6.5e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBZ37040.1 - 6.4e-07 29.0 0.0 9.1e-05 21.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBZ37040.1 - 5.9e-06 26.3 0.0 3.5e-05 23.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 CBZ37040.1 - 0.0016 18.2 0.5 0.0043 16.8 0.5 1.8 1 0 0 1 1 1 1 AAA lid domain HisKA PF00512.25 CBZ37040.1 - 0.0073 16.3 0.1 0.34 11.0 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_3 PF07726.11 CBZ37040.1 - 0.012 15.5 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBZ37040.1 - 0.14 11.9 0.0 0.84 9.3 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain TBCA PF02970.16 CBZ37041.1 - 4.1e-17 62.3 1.4 5.6e-17 61.8 1.4 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Spc7 PF08317.11 CBZ37041.1 - 0.0054 15.7 0.9 0.0063 15.4 0.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein EIAV_Rev PF11129.8 CBZ37041.1 - 0.099 12.9 0.7 0.32 11.2 0.3 1.8 1 1 1 2 2 2 0 Rev protein of equine infectious anaemia virus Phosducin PF02114.16 CBZ37042.1 - 1.6e-10 40.4 0.1 1.9e-10 40.2 0.1 1.0 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 CBZ37042.1 - 1.4e-08 34.7 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 CBZ37042.1 - 0.003 17.4 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein MnmE_helical PF12631.7 CBZ37042.1 - 0.022 14.9 0.1 0.022 14.9 0.1 1.1 1 0 0 1 1 1 0 MnmE helical domain Thioredoxin_3 PF13192.6 CBZ37042.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain Rab5ip PF07019.12 CBZ37045.1 - 3e-18 66.2 7.1 3.5e-18 65.9 7.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Sec16 PF12932.7 CBZ37045.1 - 0.19 12.3 0.1 0.24 12.0 0.1 1.2 1 0 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region DUF21 PF01595.20 CBZ37047.1 - 2.2e-37 128.5 1.3 3.2e-37 127.9 1.3 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain Bax1-I PF01027.20 CBZ37047.1 - 0.46 10.3 8.8 0.42 10.4 2.3 2.2 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 LRR_4 PF12799.7 CBZ37048.1 - 1.2e-16 60.6 15.8 1.7e-08 34.6 3.0 3.7 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) AMPK1_CBM PF16561.5 CBZ37048.1 - 4.6e-14 52.4 0.0 1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase SCAB-Ig PF16709.5 CBZ37048.1 - 1.3e-12 47.6 0.1 0.00018 21.5 0.0 5.1 4 1 1 5 5 5 3 Ig domain of plant-specific actin-binding protein LRR_9 PF14580.6 CBZ37048.1 - 2.7e-10 40.0 0.1 5.4e-06 26.0 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CBZ37048.1 - 2e-09 37.0 8.4 0.00014 21.6 2.0 3.4 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 CBZ37048.1 - 0.0044 17.0 12.2 2.7 8.3 0.1 5.0 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 CBZ37048.1 - 0.0052 17.1 2.2 53 4.9 0.2 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat CBM_48 PF02922.18 CBZ37048.1 - 0.054 13.8 0.4 0.42 11.0 0.0 2.6 3 0 0 3 3 3 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) MMR_HSR1 PF01926.23 CBZ37049.1 - 5e-13 49.1 0.0 1.1e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ37049.1 - 8.6e-07 29.0 0.2 5.2e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 CBZ37049.1 - 0.0014 18.2 0.0 0.31 10.5 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CBZ37049.1 - 0.028 14.8 0.0 0.11 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CBZ37049.1 - 0.033 14.7 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DnaJ PF00226.31 CBZ37050.1 - 2.3e-20 72.5 0.0 4.4e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.28 CBZ37051.1 - 1.6e-36 126.7 0.1 2.2e-36 126.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ37051.1 - 0.022 15.2 0.1 0.046 14.2 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Roc PF08477.13 CBZ37052.1 - 1.2e-14 54.5 0.0 2.5e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ37052.1 - 2.4e-11 43.5 0.1 5.8e-11 42.2 0.1 1.6 1 1 0 1 1 1 1 Ras family COR PF16095.5 CBZ37052.1 - 3.9e-09 36.6 0.1 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain IBR PF01485.21 CBZ37052.1 - 0.00034 20.8 0.3 0.00079 19.6 0.3 1.5 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain Gtr1_RagA PF04670.12 CBZ37052.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region YdjO PF14169.6 CBZ37052.1 - 0.044 13.5 0.3 0.091 12.5 0.3 1.4 1 0 0 1 1 1 0 Cold-inducible protein YdjO DUF3082 PF11282.8 CBZ37054.1 - 0.016 15.4 1.3 0.03 14.6 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3082) zf-MIZ PF02891.20 CBZ37055.1 - 9.5e-11 41.3 6.2 1.9e-10 40.3 6.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CBZ37055.1 - 1.9e-06 27.6 1.4 4.3e-06 26.4 1.4 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 CBZ37055.1 - 0.073 13.1 0.1 0.073 13.1 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon DUF2072 PF09845.9 CBZ37055.1 - 0.17 12.2 0.1 0.39 11.0 0.1 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein zf-NADH-PPase PF09297.11 CBZ37055.1 - 2.3 7.9 10.4 0.27 10.9 4.9 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain ABC_tran PF00005.27 CBZ37056.1 - 7.2e-35 120.5 0.0 2.6e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 CBZ37056.1 - 1.8e-33 116.4 6.4 2.4e-33 116.0 6.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CBZ37056.1 - 2e-05 24.1 0.3 0.0028 17.1 0.3 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBZ37056.1 - 0.0011 19.4 0.6 0.0022 18.4 0.1 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CBZ37056.1 - 0.0014 18.4 1.3 0.013 15.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBZ37056.1 - 0.0031 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CBZ37056.1 - 0.0063 16.8 0.1 0.084 13.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CBZ37056.1 - 0.023 15.2 0.3 0.13 12.7 0.3 2.0 1 1 1 2 2 2 0 AAA domain AAA_21 PF13304.6 CBZ37056.1 - 0.042 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CBZ37056.1 - 0.072 13.2 0.0 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CBZ37056.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CBZ37056.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FSH1 PF03959.13 CBZ37059.1 - 1.9e-29 102.8 0.0 2.9e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) MMR_HSR1_C PF08438.10 CBZ37059.1 - 4.4e-24 85.2 0.0 1.1e-23 84.0 0.0 1.7 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CBZ37059.1 - 8.8e-15 54.8 0.0 4.2e-14 52.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ37059.1 - 0.00095 18.7 0.1 0.0092 15.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RWD PF05773.22 CBZ37059.1 - 0.025 14.9 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 RWD domain Hydrolase_4 PF12146.8 CBZ37059.1 - 0.06 12.6 0.8 0.65 9.2 0.0 2.5 1 1 0 2 2 2 0 Serine aminopeptidase, S33 ATP_bind_1 PF03029.17 CBZ37059.1 - 0.1 12.4 0.0 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 CBZ37059.1 - 0.11 11.5 0.2 0.95 8.4 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ribosomal_L3 PF00297.22 CBZ37060.1 - 9.8e-45 153.1 0.2 1.1e-44 153.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Aldedh PF00171.22 CBZ37062.1 - 1.7e-18 66.4 1.4 3.4e-14 52.2 0.3 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family IQ PF00612.27 CBZ37063.1 - 3.2e-22 76.2 90.3 5.3e-06 25.8 4.8 10.4 10 0 0 10 10 10 9 IQ calmodulin-binding motif TPR_2 PF07719.17 CBZ37063.1 - 0.00036 20.4 0.1 2.8 8.3 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ37063.1 - 0.0025 17.6 0.0 0.0025 17.6 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ37063.1 - 0.014 15.4 1.0 2.4 8.4 0.0 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ37063.1 - 0.023 14.5 0.0 12 5.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.6 CBZ37064.1 - 8.3e-07 28.6 9.8 0.024 14.7 0.2 4.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 CBZ37064.1 - 8.7e-06 26.0 2.7 0.0008 19.8 1.5 3.5 2 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ37064.1 - 0.0034 17.1 2.1 0.076 12.8 1.4 2.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 CBZ37064.1 - 0.15 12.7 2.3 9.9 7.2 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat L51_S25_CI-B8 PF05047.16 CBZ37065.1 - 0.0065 16.4 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain COG5 PF10392.9 CBZ37067.1 - 3.1e-13 50.1 17.7 7.5e-13 48.8 3.2 3.7 3 0 0 3 3 3 2 Golgi transport complex subunit 5 DUF1664 PF07889.12 CBZ37067.1 - 0.0031 17.5 2.2 0.0074 16.3 1.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) COG2 PF06148.11 CBZ37067.1 - 1.5 8.9 4.1 2.6 8.1 1.5 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Roc PF08477.13 CBZ37069.1 - 1.5e-08 34.9 0.1 1.1e-07 32.1 0.1 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ37069.1 - 4.3e-06 26.3 0.1 0.00031 20.3 0.2 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CBZ37069.1 - 1.9e-05 24.3 0.0 6.6e-05 22.6 0.0 1.8 2 1 0 2 2 2 1 Ras family G-alpha PF00503.20 CBZ37069.1 - 9.9e-05 21.6 0.0 0.15 11.2 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 CBZ37069.1 - 0.00029 20.9 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ37069.1 - 0.0073 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CBZ37069.1 - 0.0081 15.9 0.1 0.021 14.6 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CBZ37069.1 - 0.022 14.2 0.2 0.051 13.0 0.2 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PA PF02225.22 CBZ37069.1 - 0.06 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 PA domain AAA_18 PF13238.6 CBZ37069.1 - 0.077 13.5 0.1 0.15 12.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CBZ37069.1 - 0.081 12.0 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.23 CBZ37069.1 - 0.082 13.0 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Dynamin family DUF3335 PF11814.8 CBZ37069.1 - 0.18 11.3 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase_C39 like family Roc PF08477.13 CBZ37071.1 - 3.5e-06 27.2 0.0 2.2e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CBZ37071.1 - 4.2e-06 27.3 0.0 9.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ37071.1 - 0.00026 21.0 0.4 0.048 13.6 0.5 2.8 1 1 1 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CBZ37071.1 - 0.00033 20.9 0.5 0.011 16.1 0.1 2.8 1 1 1 2 2 2 1 AAA domain GTP_EFTU PF00009.27 CBZ37071.1 - 0.00094 18.8 0.0 0.79 9.2 0.0 2.7 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain G-alpha PF00503.20 CBZ37071.1 - 0.0019 17.5 0.0 0.02 14.1 0.1 2.1 2 0 0 2 2 2 1 G-protein alpha subunit NACHT PF05729.12 CBZ37071.1 - 0.002 18.1 0.0 0.0075 16.2 0.0 1.9 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 CBZ37071.1 - 0.0034 17.9 0.0 0.0069 16.9 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 CBZ37071.1 - 0.0048 17.1 1.4 0.023 14.9 0.1 2.6 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.6 CBZ37071.1 - 0.011 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 CBZ37071.1 - 0.026 14.1 0.3 0.23 11.0 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 CBZ37071.1 - 0.027 13.7 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 CBZ37071.1 - 0.029 13.7 0.0 0.071 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Arf PF00025.21 CBZ37071.1 - 0.03 13.8 0.0 0.21 11.0 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family ATP_bind_1 PF03029.17 CBZ37071.1 - 0.035 13.9 0.7 2 8.2 0.5 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.12 CBZ37071.1 - 0.042 13.3 0.0 0.094 12.2 0.0 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein MobB PF03205.14 CBZ37071.1 - 0.044 13.7 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 CBZ37071.1 - 0.046 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DAP3 PF10236.9 CBZ37071.1 - 0.069 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.10 CBZ37071.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 CBZ37071.1 - 0.11 12.2 0.9 1.4 8.6 0.1 2.7 2 1 1 3 3 3 0 AAA domain Ras PF00071.22 CBZ37071.1 - 0.14 11.7 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Ras family Pkinase PF00069.25 CBZ37073.1 - 1.5e-74 250.7 0.0 2e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37073.1 - 6.1e-35 120.8 0.0 2.9e-34 118.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CBZ37073.1 - 0.002 17.7 0.1 0.0035 17.0 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 CBZ37073.1 - 0.017 14.4 0.0 0.041 13.2 0.0 1.4 1 1 0 1 1 1 0 Kinase-like FTA2 PF13095.6 CBZ37073.1 - 0.02 14.5 0.0 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CBZ37073.1 - 0.045 12.7 0.1 0.072 12.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CBZ37073.1 - 0.046 12.8 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Glucosamine_iso PF01182.20 CBZ37074.1 - 2.4e-20 73.4 0.0 3.1e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Cpn60_TCP1 PF00118.24 CBZ37075.1 - 2.8e-147 491.3 10.5 3.2e-147 491.1 10.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MotA_ExbB PF01618.16 CBZ37077.1 - 1.2 8.8 0.0 1.2 8.8 0.0 2.5 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family DnaJ_C PF01556.18 CBZ37078.1 - 1.4e-27 96.6 0.0 1.9e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ37078.1 - 5.5e-17 61.6 5.9 8.8e-17 61.0 5.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ37078.1 - 5.6e-12 45.8 12.9 9e-12 45.2 12.9 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ37078.1 - 4.5e-06 26.5 9.1 0.0088 16.0 0.9 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 CBZ37078.1 - 0.55 10.3 10.1 5.8 7.0 10.1 2.1 1 1 0 1 1 1 0 Double zinc ribbon A2L_zn_ribbon PF08792.10 CBZ37078.1 - 0.58 9.9 13.9 0.63 9.8 0.0 3.3 3 1 1 4 4 4 0 A2L zinc ribbon domain HypA PF01155.19 CBZ37078.1 - 2.1 8.4 8.9 27 4.8 8.9 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NMD3 PF04981.13 CBZ37078.1 - 3.9 6.9 9.4 0.88 9.0 0.1 2.5 3 0 0 3 3 3 0 NMD3 family Zn-ribbon_8 PF09723.10 CBZ37078.1 - 4.1 7.6 10.7 0.15 12.2 1.8 2.9 1 1 3 4 4 4 0 Zinc ribbon domain Pyr_redox_2 PF07992.14 CBZ37079.1 - 1.2e-68 231.5 9.1 3.6e-68 230.0 5.6 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CBZ37079.1 - 2.1e-39 134.2 0.4 4.9e-39 133.0 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CBZ37079.1 - 9.9e-19 67.7 11.6 1.9e-17 63.5 2.0 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBZ37079.1 - 6.2e-16 58.5 7.9 2e-13 50.3 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CBZ37079.1 - 5.5e-10 39.2 0.8 5.5e-10 39.2 0.8 3.3 3 1 1 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.22 CBZ37079.1 - 6.2e-10 38.7 2.9 6.2e-10 38.7 2.9 2.9 2 2 1 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CBZ37079.1 - 1.6e-07 31.5 5.7 4.2e-05 23.7 0.8 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CBZ37079.1 - 1e-06 28.1 1.1 1e-06 28.1 1.1 3.9 2 1 2 4 4 4 1 FAD binding domain Thi4 PF01946.17 CBZ37079.1 - 8.2e-06 25.2 1.3 0.00017 20.9 0.1 2.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 CBZ37079.1 - 9e-06 25.2 12.6 0.02 14.2 0.6 3.2 2 1 1 3 3 3 3 FAD binding domain K_oxygenase PF13434.6 CBZ37079.1 - 1.3e-05 24.5 0.3 0.02 14.1 0.0 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CBZ37079.1 - 6.7e-05 22.3 9.4 0.0031 16.9 0.7 3.1 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CBZ37079.1 - 0.00047 19.0 1.1 0.00047 19.0 1.1 3.8 3 1 1 4 4 4 1 HI0933-like protein 3HCDH_N PF02737.18 CBZ37079.1 - 0.0022 17.9 0.8 0.0022 17.9 0.8 2.9 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 CBZ37079.1 - 0.037 14.5 0.2 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.6 CBZ37079.1 - 0.068 13.6 1.7 0.59 10.6 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 CBZ37079.1 - 0.45 9.5 3.0 3 6.8 0.0 2.5 2 1 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 CBZ37079.1 - 2 7.9 17.4 3.2 7.2 3.4 3.5 2 2 1 4 4 4 0 FAD dependent oxidoreductase Cyclin_N PF00134.23 CBZ37080.1 - 1.2e-38 131.7 3.7 3.9e-38 130.1 0.8 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CBZ37080.1 - 1.3e-31 109.2 0.1 3.2e-31 107.9 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 CBZ37080.1 - 0.011 16.0 0.2 0.029 14.8 0.0 1.8 2 0 0 2 2 2 0 Cyclin C-terminal domain TMEMspv1-c74-12 PF11044.8 CBZ37081.1 - 0.021 14.8 1.1 0.033 14.2 0.3 1.8 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Na_H_antiporter PF03553.14 CBZ37081.1 - 0.059 12.6 0.0 0.07 12.3 0.0 1.0 1 0 0 1 1 1 0 Na+/H+ antiporter family GlnD_UR_UTase PF08335.11 CBZ37082.1 - 0.17 12.0 0.3 1.3 9.1 0.3 2.5 1 1 0 1 1 1 0 GlnD PII-uridylyltransferase zf-B_box PF00643.24 CBZ37083.1 - 1.6e-07 31.3 3.4 4.1e-07 30.0 3.4 1.7 1 0 0 1 1 1 1 B-box zinc finger SesA PF17107.5 CBZ37083.1 - 0.75 10.0 3.1 1.8 8.8 0.0 2.6 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Exonuc_VII_L PF02601.15 CBZ37083.1 - 4.9 6.6 7.3 1.6 8.2 3.3 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Lipase_3 PF01764.25 CBZ37084.1 - 6.2e-11 42.3 0.1 1.6e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 CBZ37084.1 - 0.017 14.4 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Voltage_CLC PF00654.20 CBZ37085.1 - 3.9e-82 276.3 26.5 8e-82 275.3 24.7 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CBZ37085.1 - 3.4e-08 33.8 0.3 0.00031 21.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain TruD PF01142.18 CBZ37086.1 - 2.7e-32 112.1 0.0 1.3e-24 86.8 0.0 3.3 3 0 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) Thiol_cytolysin PF01289.19 CBZ37086.1 - 0.13 11.2 0.0 0.31 9.9 0.0 1.5 2 0 0 2 2 2 0 Thiol-activated cytolysin zf-MYND PF01753.18 CBZ37087.1 - 0.0068 16.5 13.3 0.0068 16.5 13.3 2.4 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 CBZ37087.1 - 0.031 14.4 9.0 0.031 14.4 6.6 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_4 PF13894.6 CBZ37087.1 - 1.3 10.0 10.3 6.9 7.8 10.3 2.4 1 0 0 1 1 1 0 C2H2-type zinc finger Abhydrolase_1 PF00561.20 CBZ37088.1 - 1.2e-06 28.4 0.1 3.8e-05 23.4 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Dopey_N PF04118.14 CBZ37089.1 - 1.1e-37 129.9 0.0 7.7e-37 127.0 0.0 2.1 1 1 0 1 1 1 1 Dopey, N-terminal Cytochrom_B_N_2 PF13631.6 CBZ37090.1 - 2.2 8.3 8.0 1.7 8.6 0.2 2.7 3 0 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB UPF0564 PF10595.9 CBZ37091.1 - 5.6e-11 42.1 21.3 8.3e-08 31.7 4.3 3.4 2 2 0 3 3 3 2 Uncharacterised protein family UPF0564 zf-C2HC_2 PF13913.6 CBZ37093.1 - 2.1e-25 88.0 14.9 2.1e-10 40.2 0.8 3.5 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zinc_ribbon_2 PF13240.6 CBZ37093.1 - 0.002 17.8 7.6 0.002 17.8 7.6 3.8 3 0 0 3 3 3 1 zinc-ribbon domain zf-RING_7 PF02591.15 CBZ37093.1 - 0.024 14.8 10.2 1.2 9.4 0.0 4.1 3 1 0 3 3 3 0 C4-type zinc ribbon domain zf-CHCC PF10276.9 CBZ37093.1 - 0.028 14.5 1.8 0.97 9.5 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_4 PF13894.6 CBZ37093.1 - 0.054 14.4 13.1 0.48 11.4 0.5 4.0 4 0 0 4 4 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 CBZ37093.1 - 0.063 12.9 10.3 1.9 8.2 0.0 4.0 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger DZR PF12773.7 CBZ37093.1 - 1.1 9.3 18.9 29 4.8 12.8 4.0 3 1 0 3 3 3 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 CBZ37093.1 - 2.1 8.7 8.4 18 5.7 0.1 4.1 4 0 0 4 4 4 0 zinc-ribbon Sgf11 PF08209.11 CBZ37093.1 - 2.6 7.7 7.2 5.4 6.7 0.2 3.6 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) NinF PF05810.12 CBZ37093.1 - 2.8 7.9 10.2 4.2 7.3 0.3 3.4 3 0 0 3 3 3 0 NinF protein DUF2318 PF10080.9 CBZ37093.1 - 3.8 7.7 10.5 11 6.2 0.1 3.8 4 0 0 4 4 4 0 Predicted membrane protein (DUF2318) Rad50_zn_hook PF04423.14 CBZ37093.1 - 4 7.4 5.9 4.8 7.1 0.0 2.7 3 0 0 3 3 3 0 Rad50 zinc hook motif zinc_ribbon_15 PF17032.5 CBZ37093.1 - 5.3 7.9 10.0 9.7 7.0 6.6 2.9 3 1 0 3 3 3 0 zinc-ribbon family TF_Zn_Ribbon PF08271.12 CBZ37093.1 - 6.2 6.4 15.1 10 5.7 0.1 4.8 5 0 0 5 5 5 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 CBZ37093.1 - 9.5 6.4 12.7 7.6 6.7 0.0 4.1 4 0 0 4 4 4 0 Zinc ribbon domain RNase_PH_C PF03725.15 CBZ37094.1 - 1.6e-06 28.0 0.0 2.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 CBZ37094.1 - 3.3e-06 27.6 0.0 6.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 FAA_hydro_N_2 PF18288.1 CBZ37094.1 - 0.043 14.2 0.1 0.1 13.0 0.1 1.6 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 RRM_1 PF00076.22 CBZ37095.1 - 2.7e-09 36.7 0.0 2.4e-06 27.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rrn6 PF10214.9 CBZ37095.1 - 2.3 6.6 12.5 3.6 5.9 12.5 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TPR_19 PF14559.6 CBZ37096.1 - 0.78 10.3 0.0 0.78 10.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 CBZ37097.1 - 8.2e-17 61.5 0.0 1.7e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ37097.1 - 0.00018 21.9 0.0 0.0014 19.0 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ37097.1 - 0.00067 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 CBZ37097.1 - 0.0096 16.3 0.0 0.55 10.7 0.0 3.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ37097.1 - 0.013 15.8 2.1 0.52 10.6 0.5 3.4 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 CBZ37097.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 CBZ37097.1 - 0.063 13.1 0.2 0.38 10.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain Robl_LC7 PF03259.17 CBZ37100.1 - 2.4e-07 30.4 0.1 1.2e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CBZ37100.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 NUDE_C PF04880.13 CBZ37100.1 - 0.17 12.4 0.4 0.3 11.5 0.4 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Methyltr_RsmB-F PF01189.17 CBZ37102.1 - 0.00035 20.3 0.0 0.0011 18.6 0.0 1.8 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F RE_XamI PF09572.10 CBZ37103.1 - 0.13 11.9 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 XamI restriction endonuclease EDR1 PF14381.6 CBZ37104.1 - 0.0083 15.9 0.1 0.012 15.3 0.1 1.2 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 LPP PF04728.13 CBZ37104.1 - 0.085 13.3 0.7 0.085 13.3 0.7 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper PH PF00169.29 CBZ37106.1 - 0.00099 19.6 0.0 0.0028 18.1 0.0 1.8 1 1 0 1 1 1 1 PH domain PH_6 PF15406.6 CBZ37106.1 - 0.083 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Syntaxin PF00804.25 CBZ37107.1 - 0.0016 18.1 0.1 0.0016 18.1 0.1 1.7 2 0 0 2 2 2 1 Syntaxin DUF503 PF04456.12 CBZ37107.1 - 0.14 12.0 0.7 0.29 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF503) MPDZ_u10 PF16667.5 CBZ37107.1 - 2 9.4 10.2 21 6.1 4.9 3.0 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein ECH_2 PF16113.5 CBZ37109.1 - 2.6e-16 60.0 0.0 2.9e-16 59.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ37110.1 - 1.8e-88 297.3 0.0 2.2e-88 297.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBZ37110.1 - 1e-16 61.0 0.0 1.8e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ37111.1 - 6.1e-104 348.1 0.0 7e-104 347.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBZ37111.1 - 5.1e-24 84.9 0.0 7.2e-23 81.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase zinc_ribbon_2 PF13240.6 CBZ37112.1 - 0.00089 18.9 1.5 0.0017 18.0 1.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain BT1 PF03092.16 CBZ37115.1 - 9.9e-27 93.3 17.9 1.8e-16 59.5 3.3 2.1 2 0 0 2 2 2 2 BT1 family TMEM18 PF14770.6 CBZ37116.1 - 2.1e-30 105.2 0.7 2.6e-30 104.8 0.7 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 RseC_MucC PF04246.12 CBZ37116.1 - 2.5 8.1 5.4 8.7 6.3 1.8 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TYW3 PF02676.14 CBZ37118.1 - 2e-50 171.1 0.0 2.3e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 Mid1 PF12929.7 CBZ37118.1 - 0.044 13.0 0.3 0.054 12.7 0.3 1.1 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component DUF4404 PF14357.6 CBZ37119.1 - 0.026 15.2 0.4 0.99 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF3106 PF11304.8 CBZ37120.1 - 0.017 15.6 6.0 0.026 15.0 6.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) CKS PF01111.19 CBZ37122.1 - 7.9e-37 125.4 0.9 9.6e-37 125.1 0.9 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit TPR_1 PF00515.28 CBZ37123.1 - 8.4e-07 28.6 1.6 0.056 13.3 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ37123.1 - 9.6e-06 25.3 6.7 0.051 13.7 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ37123.1 - 0.00012 22.3 3.9 0.039 14.2 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ37123.1 - 0.0068 16.5 0.2 0.74 10.2 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ37123.1 - 0.047 13.6 1.5 4.8 7.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ37123.1 - 3 8.7 10.4 14 6.6 0.3 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat SHQ1 PF04925.15 CBZ37124.1 - 1e-33 116.4 0.0 2.5e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 SHQ1 protein WD40 PF00400.32 CBZ37125.1 - 7e-05 23.5 2.4 1.7 9.7 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37125.1 - 0.00021 21.5 0.0 9.7 6.6 0.0 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cornichon PF03311.14 CBZ37126.1 - 1.1e-15 58.0 7.2 1.1e-15 58.0 7.2 1.6 1 1 0 1 1 1 1 Cornichon protein Pox_P21 PF05313.12 CBZ37126.1 - 0.013 15.1 0.2 0.013 15.1 0.2 2.1 3 0 0 3 3 3 0 Poxvirus P21 membrane protein DUF4212 PF13937.6 CBZ37126.1 - 0.024 15.0 3.0 0.024 15.0 3.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4212) Cornichon PF03311.14 CBZ37127.1 - 5.7e-26 91.2 3.0 5.7e-26 91.2 3.0 1.8 1 1 1 2 2 2 1 Cornichon protein HAUS-augmin3 PF14932.6 CBZ37128.1 - 0.00015 21.4 9.9 0.0033 17.1 0.2 2.1 1 1 1 2 2 2 2 HAUS augmin-like complex subunit 3 Wtap PF17098.5 CBZ37128.1 - 0.00016 21.7 10.7 0.013 15.4 4.4 2.7 1 1 2 3 3 3 2 WTAP/Mum2p family TSKS PF15358.6 CBZ37128.1 - 0.0086 14.5 8.9 0.018 13.4 0.4 2.3 1 1 1 2 2 2 2 Testis-specific serine kinase substrate Dsh_C PF12316.8 CBZ37128.1 - 0.016 15.7 1.6 0.031 14.7 1.6 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF1192 PF06698.11 CBZ37128.1 - 0.016 15.2 9.0 1.7 8.7 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) CENP-K PF11802.8 CBZ37128.1 - 0.027 14.1 1.7 0.036 13.7 0.6 1.7 2 0 0 2 2 2 0 Centromere-associated protein K SGT1 PF07093.11 CBZ37128.1 - 0.032 12.7 0.3 0.036 12.5 0.3 1.1 1 0 0 1 1 1 0 SGT1 protein DUF5044 PF16447.5 CBZ37128.1 - 0.034 14.0 0.1 15 5.4 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5044) Med26_C PF15693.5 CBZ37128.1 - 0.068 13.3 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal ABC_tran_CTD PF16326.5 CBZ37128.1 - 0.11 12.7 6.3 1.1 9.6 0.5 2.7 2 1 1 3 3 3 0 ABC transporter C-terminal domain Spc7 PF08317.11 CBZ37128.1 - 0.15 10.9 7.7 1.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein GIT_CC PF16559.5 CBZ37128.1 - 0.2 11.5 2.4 0.3 11.0 0.2 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc24 PF08286.11 CBZ37128.1 - 0.34 11.2 5.2 1.3 9.2 1.2 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 NYD-SP28_assoc PF14775.6 CBZ37128.1 - 0.36 11.0 5.5 0.29 11.2 0.7 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain SIKE PF05769.11 CBZ37128.1 - 0.44 10.5 8.4 0.32 10.9 0.2 2.7 3 0 0 3 3 3 0 SIKE family Swi5 PF07061.11 CBZ37128.1 - 0.45 10.6 2.3 1.7 8.8 0.4 2.4 2 0 0 2 2 2 0 Swi5 HrpB7 PF09486.10 CBZ37128.1 - 0.66 10.3 18.6 1.7 9.0 0.9 2.7 2 2 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) ADIP PF11559.8 CBZ37128.1 - 0.92 9.6 9.9 8 6.5 0.2 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Med9 PF07544.13 CBZ37128.1 - 1.1 9.4 7.6 7 6.8 1.3 3.2 3 1 0 4 4 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF812 PF05667.11 CBZ37128.1 - 1.1 8.0 8.0 0.66 8.8 4.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF812) YabA PF06156.13 CBZ37128.1 - 1.5 9.5 8.4 50 4.6 4.6 3.2 2 1 0 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 CBZ37128.1 - 2.4 7.2 7.5 2.7 7.0 4.8 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TolA_bind_tri PF16331.5 CBZ37128.1 - 4.7 7.4 20.0 7.1 6.8 7.5 3.8 2 2 2 4 4 4 0 TolA binding protein trimerisation DivIC PF04977.15 CBZ37128.1 - 4.8 7.0 7.6 1.2 9.0 2.4 2.4 2 1 0 2 2 2 0 Septum formation initiator DUF737 PF05300.11 CBZ37129.1 - 0.12 12.7 1.5 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) Myosin_head PF00063.21 CBZ37130.1 - 5.9e-176 586.6 0.0 8.6e-176 586.1 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) UBA PF00627.31 CBZ37130.1 - 1.2e-07 31.5 0.3 0.00043 20.1 0.1 2.8 2 0 0 2 2 2 2 UBA/TS-N domain AAA_lid_6 PF17866.1 CBZ37130.1 - 0.0015 18.6 0.5 0.2 11.8 0.0 3.4 3 0 0 3 3 3 1 AAA lid domain AAA_16 PF13191.6 CBZ37130.1 - 0.0015 18.9 2.3 0.52 10.7 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain CUE PF02845.16 CBZ37130.1 - 0.0028 17.3 0.3 13 5.6 0.0 3.9 3 0 0 3 3 3 1 CUE domain Mg_chelatase PF01078.21 CBZ37130.1 - 0.0062 15.9 0.1 0.031 13.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CBZ37130.1 - 0.0063 16.8 0.0 0.041 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.19 CBZ37130.1 - 0.016 15.0 0.2 0.049 13.5 0.2 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain DUF2972 PF11186.8 CBZ37130.1 - 0.18 11.7 1.1 0.95 9.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2972) Pet100 PF09803.9 CBZ37130.1 - 0.54 10.8 4.0 0.57 10.7 0.1 2.6 2 0 0 2 2 2 0 Pet100 Peptidase_C54 PF03416.19 CBZ37132.1 - 1.1e-43 149.7 0.0 1.4e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 COPIIcoated_ERV PF07970.12 CBZ37133.1 - 8.4e-37 127.2 0.2 1.1e-36 126.8 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CBZ37133.1 - 6e-24 84.2 0.2 1.1e-23 83.4 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF5534 PF17686.1 CBZ37133.1 - 0.5 10.6 3.0 18 5.5 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5534) ERCC3_RAD25_C PF16203.5 CBZ37134.1 - 2e-70 236.9 0.2 1.2e-69 234.2 0.0 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CBZ37134.1 - 6.1e-19 68.4 0.4 1.5e-18 67.1 0.4 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ37134.1 - 1.9e-12 47.5 0.0 3.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CBZ37134.1 - 3e-10 40.4 0.3 1e-09 38.7 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CBZ37134.1 - 4e-05 22.5 0.0 0.00011 21.1 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF2089 PF09862.9 CBZ37134.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) HECT PF00632.25 CBZ37135.1 - 6.7e-39 134.2 0.7 2.1e-38 132.6 0.7 1.8 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBZ37135.1 - 2.1e-27 95.6 0.0 4.4e-07 30.1 0.0 5.2 5 0 0 5 5 5 4 SPRY domain ZZ PF00569.17 CBZ37135.1 - 0.00096 18.9 8.7 0.0023 17.7 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.20 CBZ37135.1 - 0.0018 18.4 3.8 0.0074 16.4 3.8 2.1 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) PIN_4 PF13638.6 CBZ37136.1 - 0.032 14.5 0.0 0.13 12.5 0.0 2.1 1 1 0 1 1 1 0 PIN domain PG_binding_1 PF01471.18 CBZ37138.1 - 0.082 13.1 0.2 0.62 10.3 0.0 2.5 3 0 0 3 3 3 0 Putative peptidoglycan binding domain CARD_2 PF16739.5 CBZ37138.1 - 0.09 12.8 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Caspase recruitment domain cNMP_binding PF00027.29 CBZ37139.1 - 4.9e-21 74.6 0.1 7.9e-08 32.3 0.0 4.1 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain GCM PF03615.15 CBZ37139.1 - 0.091 12.7 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 GCM motif protein Gar1 PF04410.14 CBZ37140.1 - 7.4e-22 77.8 0.0 9.8e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Glycos_transf_2 PF00535.26 CBZ37141.1 - 8.8e-08 32.1 0.0 1.7e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 PRCC PF10253.9 CBZ37141.1 - 0.046 14.5 0.2 0.074 13.8 0.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting LysM PF01476.20 CBZ37142.1 - 1.1e-07 31.8 0.0 0.033 14.3 0.0 3.2 3 0 0 3 3 3 2 LysM domain HTH_AsnC-type PF13404.6 CBZ37142.1 - 0.00066 19.5 0.5 2.3 8.1 0.0 4.4 4 0 0 4 4 4 1 AsnC-type helix-turn-helix domain HTH_23 PF13384.6 CBZ37142.1 - 0.0013 18.5 0.0 6.5 6.7 0.0 3.6 3 0 0 3 3 3 2 Homeodomain-like domain Death PF00531.22 CBZ37142.1 - 0.013 15.7 0.0 5.5 7.2 0.0 3.3 3 0 0 3 3 3 0 Death domain DUF3606 PF12244.8 CBZ37142.1 - 0.014 15.3 0.3 0.85 9.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3606) Fringe PF02434.16 CBZ37142.1 - 0.053 13.0 0.1 0.14 11.6 0.1 1.6 2 0 0 2 2 2 0 Fringe-like Herpes_UL52 PF03121.15 CBZ37144.1 - 3.2e-11 43.0 0.1 9.7e-11 41.5 0.1 1.8 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase DUF4110 PF13422.6 CBZ37144.1 - 0.2 11.8 0.0 0.36 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) FOP_dimer PF09398.10 CBZ37146.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.3 1 0 0 1 1 1 0 FOP N terminal dimerisation domain WD40 PF00400.32 CBZ37147.1 - 6.5e-27 93.2 13.1 2e-06 28.4 0.2 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37147.1 - 2.1e-17 63.2 1.2 0.0031 17.8 0.0 5.4 1 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CBZ37147.1 - 1e-06 28.6 0.1 0.0019 17.8 0.0 2.2 1 1 2 3 3 3 2 PQQ-like domain Ge1_WD40 PF16529.5 CBZ37147.1 - 0.00063 18.8 0.5 1.6 7.6 0.0 3.6 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WDCP PF15390.6 CBZ37147.1 - 0.0029 16.1 0.5 0.0051 15.3 0.5 1.3 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family Frtz PF11768.8 CBZ37147.1 - 0.006 15.0 0.1 0.27 9.5 0.0 2.6 1 1 2 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 CBZ37147.1 - 0.011 15.6 0.0 1.9 8.6 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat WD40_like PF17005.5 CBZ37147.1 - 0.013 14.9 0.0 0.25 10.6 0.0 2.5 2 1 0 3 3 3 0 WD40-like domain PQQ_3 PF13570.6 CBZ37147.1 - 0.054 14.0 1.2 12 6.6 0.1 4.0 4 1 0 4 4 4 0 PQQ-like domain PD40 PF07676.12 CBZ37147.1 - 0.1 12.5 0.0 11 6.1 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat HEAT PF02985.22 CBZ37148.1 - 5.5e-06 26.2 0.1 0.074 13.3 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat UVR PF02151.19 CBZ37148.1 - 0.0039 16.9 4.3 0.18 11.6 0.3 2.6 2 0 0 2 2 2 2 UvrB/uvrC motif HEAT_EZ PF13513.6 CBZ37148.1 - 0.021 15.3 1.1 0.15 12.6 0.0 2.8 3 0 0 3 3 3 0 HEAT-like repeat HEAT_2 PF13646.6 CBZ37148.1 - 0.035 14.5 0.9 3.2 8.2 0.0 3.0 2 1 1 3 3 3 0 HEAT repeats Cnd3 PF12719.7 CBZ37148.1 - 0.09 12.0 0.0 0.21 10.7 0.0 1.6 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain RecX PF02631.16 CBZ37149.1 - 0.096 13.1 0.9 0.16 12.4 0.9 1.3 1 0 0 1 1 1 0 RecX family Zip PF02535.22 CBZ37151.1 - 2.8e-12 46.5 18.8 1.1e-07 31.4 0.5 3.1 2 1 1 3 3 3 3 ZIP Zinc transporter DUF5525 PF17663.1 CBZ37151.1 - 0.46 8.5 2.5 0.59 8.1 2.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) CEP19 PF14933.6 CBZ37154.1 - 1e-52 178.8 0.0 1.7e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 CEP19-like protein Nop PF01798.18 CBZ37155.1 - 8e-46 156.4 0.0 9.4e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Aminotran_1_2 PF00155.21 CBZ37155.1 - 0.2 10.8 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Ank_2 PF12796.7 CBZ37156.1 - 3.1e-10 40.5 0.6 5.1e-08 33.4 0.1 2.7 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ37156.1 - 4.3e-07 29.7 0.3 0.013 16.0 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CBZ37156.1 - 5.4e-07 30.0 3.2 0.0013 19.3 0.2 3.9 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ37156.1 - 6.4e-06 26.3 2.4 0.0031 17.8 0.3 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ37156.1 - 0.00047 20.5 6.1 0.00085 19.7 0.5 3.8 4 0 0 4 4 4 1 Ankyrin repeat Iwr1 PF08574.10 CBZ37157.1 - 4.4e-05 24.4 2.7 4.4e-05 24.4 2.7 1.9 2 0 0 2 2 2 1 Transcription factor Iwr1 RANK_CRD_2 PF18278.1 CBZ37157.1 - 0.017 15.3 0.0 0.055 13.6 0.0 1.9 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 DUF4064 PF13273.6 CBZ37158.1 - 0.007 16.6 1.1 2 8.7 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) Tetraspanin PF00335.20 CBZ37159.1 - 1.4e-12 47.9 14.2 2e-12 47.3 14.2 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF1772 PF08592.11 CBZ37159.1 - 0.3 11.4 9.4 1.1 9.6 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) CTF_NFI PF00859.18 CBZ37161.1 - 0.024 14.5 2.6 0.037 14.0 1.4 1.8 2 0 0 2 2 2 0 CTF/NF-I family transcription modulation region DUF3486 PF11985.8 CBZ37161.1 - 0.057 13.8 0.1 0.099 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Peptidase_M14 PF00246.24 CBZ37162.1 - 4e-11 43.3 0.0 8.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 CBZ37162.1 - 1.5e-07 31.8 0.0 1.5e-07 31.8 0.0 2.5 3 0 0 3 3 3 1 Cytosolic carboxypeptidase N-terminal domain DUF4926 PF16277.5 CBZ37164.1 - 0.018 14.4 0.2 0.034 13.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) DHHC PF01529.20 CBZ37165.1 - 2.9e-47 160.1 3.6 2.9e-47 160.1 3.6 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase A_deamin PF02137.18 CBZ37166.1 - 3.2e-18 66.3 0.0 5.2e-18 65.6 0.0 1.5 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain GST_C_5 PF16865.5 CBZ37167.1 - 5.4e-103 339.0 0.7 1.6e-53 179.9 0.1 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CBZ37167.1 - 9.1e-31 106.1 0.1 2e-14 53.7 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CBZ37167.1 - 3.2e-26 91.4 0.1 2.2e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CBZ37167.1 - 3e-19 69.1 0.2 3.9e-09 36.7 0.0 2.9 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CBZ37167.1 - 6.9e-14 51.6 1.5 2.5e-06 27.4 0.1 2.7 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CBZ37167.1 - 2.9e-11 43.4 0.2 7.7e-09 35.6 0.1 2.5 2 0 0 2 2 2 1 Glutaredoxin GST_C_3 PF14497.6 CBZ37167.1 - 3.2e-05 24.0 0.1 0.0066 16.6 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBZ37167.1 - 0.00017 21.7 0.0 0.045 14.0 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.22 CBZ37169.1 - 2.3e-09 36.9 0.0 3.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBZ37169.1 - 0.0018 18.3 0.0 0.0031 17.5 0.0 1.5 1 1 0 1 1 1 1 RNA binding motif RRM_occluded PF16842.5 CBZ37169.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Mpv17_PMP22 PF04117.12 CBZ37170.1 - 4.4e-08 33.2 0.9 8.5e-08 32.3 0.9 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family WD40 PF00400.32 CBZ37171.1 - 6.3e-18 64.8 13.3 0.00087 20.1 0.0 7.3 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37171.1 - 2.4e-07 30.9 0.0 1 9.7 0.0 4.4 3 2 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain CSTF1_dimer PF16699.5 CBZ37171.1 - 0.0049 16.6 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain GNAT_acetyltran PF12746.7 CBZ37171.1 - 0.029 13.9 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Ge1_WD40 PF16529.5 CBZ37171.1 - 0.039 12.9 0.0 9 5.1 0.0 3.2 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LAL_C2 PF18603.1 CBZ37171.1 - 0.53 10.5 3.4 0.28 11.4 0.2 2.3 3 0 0 3 3 3 0 L-amino acid ligase C-terminal domain 2 Sugar_tr PF00083.24 CBZ37172.1 - 6.3e-140 467.0 29.4 7.9e-140 466.7 29.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBZ37172.1 - 2.8e-11 43.0 27.5 2.8e-11 43.0 27.5 2.3 2 1 1 3 3 3 1 Major Facilitator Superfamily YlmH_RBD PF17774.1 CBZ37172.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH Autophagy_N PF03986.13 CBZ37173.1 - 2.3e-26 92.4 0.5 3.5e-26 91.8 0.5 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CBZ37173.1 - 1e-18 67.7 1.2 2.1e-18 66.7 1.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CBZ37173.1 - 6.6e-11 41.5 0.7 1.5e-10 40.4 0.7 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Beta_propel PF09826.9 CBZ37173.1 - 0.045 12.6 0.4 0.054 12.3 0.4 1.1 1 0 0 1 1 1 0 Beta propeller domain Glycos_transf_2 PF00535.26 CBZ37174.1 - 0.096 12.5 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 BRAP2 PF07576.12 CBZ37174.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 ABC_tran PF00005.27 CBZ37175.1 - 1.4e-44 152.0 0.1 1.2e-20 74.5 0.0 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 CBZ37175.1 - 2.4e-17 63.7 1.0 0.00056 19.8 0.0 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ37175.1 - 1.3e-10 41.1 5.1 0.00014 21.3 0.0 5.1 4 2 1 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ37175.1 - 9.6e-08 31.7 0.3 0.014 15.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBZ37175.1 - 1.3e-07 31.7 1.3 0.0082 16.1 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_28 PF13521.6 CBZ37175.1 - 7.8e-05 23.0 0.2 0.07 13.4 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CBZ37175.1 - 0.00025 21.3 0.0 0.4 10.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ37175.1 - 0.00071 20.0 1.2 1.5 9.2 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 CBZ37175.1 - 0.0009 19.3 0.0 0.31 11.1 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CBZ37175.1 - 0.0011 19.3 0.0 0.93 9.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 CBZ37175.1 - 0.0012 19.2 0.2 1.3 9.5 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CBZ37175.1 - 0.0026 18.3 0.4 0.092 13.2 0.1 4.8 6 0 0 6 6 4 2 AAA domain AAA_5 PF07728.14 CBZ37175.1 - 0.0032 17.5 0.2 1.6 8.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CBZ37175.1 - 0.0038 17.3 0.0 1.8 8.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_tran_Xtn PF12848.7 CBZ37175.1 - 0.0041 17.1 3.1 0.0041 17.1 3.1 4.0 3 1 1 4 4 3 1 ABC transporter AAA_33 PF13671.6 CBZ37175.1 - 0.0041 17.3 0.7 0.99 9.6 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.6 CBZ37175.1 - 0.0074 16.0 3.3 0.76 9.5 0.0 3.7 2 1 1 3 3 3 1 AAA domain AAA_15 PF13175.6 CBZ37175.1 - 0.014 15.1 11.7 0.38 10.4 0.0 4.7 4 1 1 5 5 4 0 AAA ATPase domain SbcCD_C PF13558.6 CBZ37175.1 - 0.018 15.2 0.5 0.77 10.0 0.1 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 CBZ37175.1 - 0.029 14.3 0.1 11 5.8 0.0 2.6 3 0 0 3 3 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 CBZ37175.1 - 0.057 13.3 0.0 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 NTPase Nbl1_Borealin_N PF10444.9 CBZ37175.1 - 1.4 8.6 5.9 0.12 12.0 0.4 2.2 2 0 0 2 2 1 0 Nbl1 / Borealin N terminal AAA_18 PF13238.6 CBZ37175.1 - 1.8 9.1 0.0 1.8 9.1 0.0 3.8 5 1 1 6 6 4 0 AAA domain HSP90 PF00183.18 CBZ37176.1 - 7e-229 761.0 27.9 9.2e-229 760.6 27.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CBZ37176.1 - 2.2e-16 60.4 0.0 4.6e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBZ37176.1 - 6.9e-11 42.1 0.0 2e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.18 CBZ37176.1 - 0.012 16.3 0.4 0.012 16.3 0.4 3.9 5 0 0 5 5 5 0 Ribosomal protein S20 HSP90 PF00183.18 CBZ37177.1 - 7e-229 761.0 27.9 9.2e-229 760.6 27.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CBZ37177.1 - 2.2e-16 60.4 0.0 4.6e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBZ37177.1 - 6.9e-11 42.1 0.0 2e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.18 CBZ37177.1 - 0.012 16.3 0.4 0.012 16.3 0.4 3.9 5 0 0 5 5 5 0 Ribosomal protein S20 HSP90 PF00183.18 CBZ37178.1 - 7e-229 761.0 27.9 9.2e-229 760.6 27.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CBZ37178.1 - 2.2e-16 60.4 0.0 4.6e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CBZ37178.1 - 6.9e-11 42.1 0.0 2e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S20p PF01649.18 CBZ37178.1 - 0.012 16.3 0.4 0.012 16.3 0.4 3.9 5 0 0 5 5 5 0 Ribosomal protein S20 WD40 PF00400.32 CBZ37179.1 - 1.1e-09 38.7 2.2 4.3e-05 24.2 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37179.1 - 0.00078 19.7 0.0 3.4 8.0 0.0 4.0 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Hydrolase_4 PF12146.8 CBZ37182.1 - 4.8e-13 48.9 1.4 1.4e-08 34.3 1.8 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ37182.1 - 2e-11 44.0 0.8 1.1e-08 35.1 1.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CBZ37182.1 - 0.0011 18.9 0.3 0.051 13.4 0.3 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CBZ37182.1 - 0.0017 19.0 5.7 0.0071 17.0 5.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBZ37182.1 - 0.004 16.7 0.1 1.9 7.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 CBZ37182.1 - 0.006 16.3 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CBZ37182.1 - 0.042 13.4 0.0 0.16 11.5 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CBZ37182.1 - 0.065 13.1 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MutS_V PF00488.21 CBZ37183.1 - 9.1e-74 247.6 0.1 1.6e-73 246.8 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CBZ37183.1 - 1.3e-27 97.2 0.5 1.3e-27 97.2 0.5 2.2 3 0 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 CBZ37183.1 - 5.6e-17 61.9 1.0 1.2e-16 60.8 1.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.6 CBZ37183.1 - 0.043 13.6 0.0 0.6 9.9 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain MutS_II PF05188.17 CBZ37183.1 - 0.087 13.1 1.0 0.32 11.3 0.1 2.3 2 0 0 2 2 2 0 MutS domain II Lipoprotein_7 PF01540.16 CBZ37183.1 - 0.13 11.6 0.9 7.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Adhesin lipoprotein MnmE_helical PF12631.7 CBZ37183.1 - 0.13 12.4 1.7 0.2 11.8 0.4 1.9 2 0 0 2 2 2 0 MnmE helical domain Tup_N PF08581.10 CBZ37183.1 - 0.43 10.9 2.0 25 5.2 0.0 3.2 3 0 0 3 3 3 0 Tup N-terminal Phage_term_sma PF07141.11 CBZ37187.1 - 0.03 14.1 0.2 0.04 13.7 0.2 1.3 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit FAD_binding_7 PF03441.14 CBZ37189.1 - 9.8e-68 227.6 1.7 9.8e-68 227.6 1.7 1.9 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CBZ37189.1 - 1.2e-32 113.2 0.0 2.2e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Fe_dep_repr_C PF02742.15 CBZ37189.1 - 0.058 13.5 0.1 7.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain SET PF00856.28 CBZ37193.1 - 1e-08 35.8 0.0 1.7e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 SET domain ADH_N PF08240.12 CBZ37194.1 - 4.3e-23 81.3 0.2 1.5e-22 79.5 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CBZ37194.1 - 2.3e-19 69.7 0.1 4.7e-19 68.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBZ37194.1 - 1.3e-05 26.2 0.0 2.8e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CBZ37194.1 - 2.7e-05 23.8 0.3 8.3e-05 22.2 0.2 1.8 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus LRR_4 PF12799.7 CBZ37195.1 - 6e-19 67.8 0.0 0.00043 20.6 0.0 8.2 6 2 1 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ37195.1 - 1.2e-13 50.6 1.2 0.0019 17.9 0.0 6.8 6 2 2 8 8 8 5 Leucine rich repeat LRR_6 PF13516.6 CBZ37195.1 - 0.028 14.5 3.6 0.29 11.3 0.2 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ37195.1 - 0.33 11.7 8.7 9.1 7.3 0.3 6.7 6 1 0 6 6 6 0 Leucine Rich Repeat NifU PF01106.17 CBZ37197.1 - 4.3e-19 68.4 0.0 1.3e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.11 CBZ37197.1 - 7.2e-13 48.4 0.2 2.2e-10 40.4 0.1 2.4 2 0 0 2 2 2 2 Scaffold protein Nfu/NifU N terminal DUF2543 PF10820.8 CBZ37197.1 - 0.01 16.0 0.8 0.021 15.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) RtcB PF01139.17 CBZ37199.1 - 6.8e-95 318.7 0.0 9.5e-95 318.2 0.0 1.2 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Polysacc_deac_2 PF04748.13 CBZ37199.1 - 0.19 10.9 0.0 0.93 8.6 0.0 1.9 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase FYVE PF01363.21 CBZ37200.1 - 0.097 12.8 15.4 0.48 10.6 15.5 1.9 1 1 0 1 1 1 0 FYVE zinc finger WD40 PF00400.32 CBZ37201.1 - 2.3 9.2 5.0 44 5.2 0.0 4.3 5 1 0 5 5 5 0 WD domain, G-beta repeat Nkap_C PF06047.11 CBZ37202.1 - 4.8e-15 55.5 0.9 1.1e-14 54.3 0.9 1.6 1 0 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain BRE1 PF08647.11 CBZ37204.1 - 3.9e-13 49.3 12.4 3.9e-13 49.3 12.4 11.2 3 2 8 13 13 13 5 BRE1 E3 ubiquitin ligase DUF3584 PF12128.8 CBZ37204.1 - 0.00027 18.6 51.7 0.00027 18.6 51.7 3.7 1 1 1 3 3 3 1 Protein of unknown function (DUF3584) DUF724 PF05266.14 CBZ37204.1 - 0.0023 17.8 3.6 0.0023 17.8 3.6 8.8 3 2 7 10 10 10 6 Protein of unknown function (DUF724) DUF4094 PF13334.6 CBZ37204.1 - 0.0075 16.7 3.8 0.0075 16.7 3.8 9.4 4 3 4 9 9 9 1 Domain of unknown function (DUF4094) AAA_13 PF13166.6 CBZ37204.1 - 0.48 9.0 116.8 0.0069 15.1 11.8 6.7 1 1 3 6 6 6 0 AAA domain rve_3 PF13683.6 CBZ37204.1 - 5.1 7.0 5.5 8.9 6.2 0.1 3.9 3 1 1 4 4 4 0 Integrase core domain IGR PF09597.10 CBZ37205.1 - 1.8e-05 24.7 0.0 3.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 IGR protein motif ANAPC3 PF12895.7 CBZ37206.1 - 0.0061 16.8 0.3 8.6 6.7 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CBZ37206.1 - 0.064 13.3 0.1 2.3e+02 2.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat IFT57 PF10498.9 CBZ37208.1 - 1e-63 215.5 5.4 1.2e-63 215.3 5.4 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 HBM PF16591.5 CBZ37208.1 - 0.00042 19.8 7.7 0.00069 19.1 7.7 1.3 1 0 0 1 1 1 1 Helical bimodular sensor domain TPR_MLP1_2 PF07926.12 CBZ37208.1 - 0.0028 17.7 10.0 0.16 12.0 1.2 2.4 2 0 0 2 2 2 2 TPR/MLP1/MLP2-like protein mRNA_stabil PF13929.6 CBZ37208.1 - 0.0044 16.1 0.8 0.014 14.4 0.7 1.8 1 1 0 1 1 1 1 mRNA stabilisation CREPT PF16566.5 CBZ37208.1 - 0.0049 17.0 5.2 0.008 16.4 5.2 1.4 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Apolipoprotein PF01442.18 CBZ37208.1 - 0.0089 15.9 12.2 0.023 14.6 12.2 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 CBZ37208.1 - 0.02 14.5 6.4 0.03 13.9 6.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CHDCT2 PF08074.11 CBZ37208.1 - 0.024 14.8 5.1 0.3 11.2 2.2 2.2 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Spc7 PF08317.11 CBZ37208.1 - 0.026 13.4 11.7 0.09 11.6 11.0 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 CBZ37208.1 - 0.036 14.3 5.9 2.7 8.3 0.3 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein FRB_dom PF08771.11 CBZ37208.1 - 0.052 14.0 0.8 0.15 12.5 0.6 1.8 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain AAA_13 PF13166.6 CBZ37208.1 - 0.084 11.5 5.1 0.1 11.2 5.1 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.12 CBZ37208.1 - 0.14 12.2 10.2 0.84 9.7 0.4 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF745 PF05335.13 CBZ37208.1 - 0.14 11.9 9.2 0.72 9.5 5.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Phage_GPO PF05929.11 CBZ37208.1 - 0.17 11.5 4.7 0.25 11.0 4.7 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF5063 PF16702.5 CBZ37208.1 - 0.24 11.8 4.5 1.4 9.3 0.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5063) Prominin PF05478.11 CBZ37208.1 - 0.36 8.8 5.3 0.45 8.4 5.3 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 CBZ37208.1 - 0.39 10.8 10.3 1.3 9.1 3.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 CBZ37208.1 - 0.49 9.9 8.8 0.52 9.9 7.4 1.7 1 1 0 1 1 1 0 fzo-like conserved region DUF2203 PF09969.9 CBZ37208.1 - 0.73 10.6 6.0 2 9.1 4.5 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) UPF0242 PF06785.11 CBZ37208.1 - 0.76 9.8 9.2 1.2 9.3 9.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 CBZ37208.1 - 1.5 7.8 11.2 2.4 7.1 9.8 1.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 CBZ37208.1 - 1.7 9.6 9.1 0.68 10.9 6.2 1.9 2 0 0 2 2 1 0 cGMP-dependent protein kinase interacting domain YjbH PF06082.11 CBZ37208.1 - 9.7 4.9 8.8 23 3.6 8.8 1.6 1 1 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Adenylsucc_synt PF00709.21 CBZ37209.1 - 0.018 14.0 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Adenylosuccinate synthetase EF-hand_7 PF13499.6 CBZ37210.1 - 4.4e-05 23.8 0.1 6.3e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ37210.1 - 0.00099 18.5 0.1 0.0037 16.7 0.0 2.0 1 1 1 2 2 2 1 EF hand EF-hand_6 PF13405.6 CBZ37210.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain HR1 PF02185.16 CBZ37211.1 - 0.01 15.9 3.0 0.01 15.9 3.0 5.7 3 1 0 4 4 4 0 Hr1 repeat Noelin-1 PF12308.8 CBZ37211.1 - 0.13 12.2 15.3 0.43 10.6 0.2 4.5 3 2 1 4 4 4 0 Neurogenesis glycoprotein WD40 PF00400.32 CBZ37213.1 - 0.0043 17.9 0.5 27 5.8 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Miga PF10265.9 CBZ37213.1 - 0.97 8.3 2.1 1.5 7.7 2.1 1.2 1 0 0 1 1 1 0 Mitoguardin ERG4_ERG24 PF01222.17 CBZ37214.1 - 1.2e-103 347.2 23.8 1.4e-103 346.9 23.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Corona_nucleoca PF00937.18 CBZ37214.1 - 0.96 8.4 6.4 1.6 7.7 6.4 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4131 PF13567.6 CBZ37214.1 - 4.9 6.8 5.6 5.1 6.7 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ANAPC3 PF12895.7 CBZ37216.1 - 0.004 17.4 3.4 0.0082 16.4 3.4 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CBZ37216.1 - 0.0047 16.9 9.3 0.15 12.3 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ37216.1 - 0.0064 16.3 7.7 0.83 9.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF658 PF04936.12 CBZ37216.1 - 0.016 14.9 0.8 0.028 14.2 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF658) TPR_19 PF14559.6 CBZ37216.1 - 0.026 15.0 1.3 0.052 14.1 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SKI PF01202.22 CBZ37216.1 - 0.15 12.1 1.0 1.8 8.7 0.1 2.3 2 0 0 2 2 2 0 Shikimate kinase TPR_16 PF13432.6 CBZ37216.1 - 0.21 12.3 5.2 0.2 12.4 1.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ37216.1 - 0.73 10.2 3.1 31 5.1 1.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PTR2 PF00854.21 CBZ37217.1 - 3.2e-36 125.0 0.0 4.1e-34 118.1 0.0 2.4 2 1 0 2 2 2 2 POT family MFS_1 PF07690.16 CBZ37217.1 - 2.9e-08 33.0 29.5 1.5e-06 27.4 12.3 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily 2C_adapt PF08793.10 CBZ37218.1 - 0.15 12.3 0.1 0.2 11.8 0.1 1.2 1 0 0 1 1 1 0 2-cysteine adaptor domain WD40 PF00400.32 CBZ37219.1 - 1.3e-14 54.3 5.6 9.5e-06 26.3 0.2 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37219.1 - 0.011 16.1 0.0 37 4.7 0.0 4.0 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CBZ37219.1 - 0.2 12.2 1.5 5.6 7.6 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain bact-PGI_C PF10432.9 CBZ37220.1 - 0.037 14.1 0.2 0.072 13.1 0.2 1.4 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal SIS domain BRF1 PF07741.13 CBZ37220.1 - 0.38 11.1 2.9 0.72 10.2 2.9 1.4 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF2040 PF09745.9 CBZ37222.1 - 0.0042 17.1 0.3 0.0087 16.1 0.3 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) PG_binding_3 PF09374.10 CBZ37222.1 - 0.077 13.3 0.0 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 Predicted Peptidoglycan domain NUP50 PF08911.11 CBZ37222.1 - 7.3 7.3 7.6 5.4 7.7 0.5 3.1 2 2 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) Cyclin PF08613.11 CBZ37224.1 - 4.6e-28 98.6 0.0 1.4e-27 97.0 0.0 1.9 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CBZ37224.1 - 9e-05 22.2 0.1 0.00015 21.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain NIF PF03031.18 CBZ37225.1 - 9.9e-19 67.6 0.2 7.9e-17 61.5 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Oxidored_FMN PF00724.20 CBZ37228.1 - 6.9e-71 239.3 0.0 1.2e-70 238.5 0.0 1.4 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pyr_redox_2 PF07992.14 CBZ37228.1 - 1e-21 77.5 3.8 5.7e-21 75.0 3.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ37228.1 - 1e-09 38.4 0.1 7.2e-09 35.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CBZ37228.1 - 8.6e-09 35.8 0.2 0.00043 20.8 0.2 3.0 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CBZ37228.1 - 3.7e-07 29.6 0.3 0.0019 17.4 0.1 3.0 2 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 CBZ37228.1 - 5.2e-07 28.7 3.6 2.3e-06 26.6 0.3 2.7 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 CBZ37228.1 - 7.2e-07 28.9 0.9 1.2e-06 28.2 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBZ37228.1 - 1.3e-06 27.9 1.7 0.00015 21.1 0.1 3.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBZ37228.1 - 1.4e-06 28.1 6.9 1.4e-05 24.9 0.4 3.8 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CBZ37228.1 - 1.6e-05 24.2 4.3 1.8e-05 24.1 1.3 2.1 2 1 0 2 2 2 1 FAD binding domain GIDA PF01134.22 CBZ37228.1 - 1.9e-05 24.0 0.9 4.3e-05 22.8 0.7 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 CBZ37228.1 - 7.9e-05 22.6 1.0 0.012 15.5 0.0 2.6 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CBZ37228.1 - 0.00034 21.0 0.3 0.02 15.3 0.1 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CBZ37228.1 - 0.00035 19.9 1.1 0.0029 16.9 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain FMO-like PF00743.19 CBZ37228.1 - 0.00095 17.7 0.1 3.6 5.9 0.0 3.1 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.23 CBZ37228.1 - 0.0014 18.6 0.1 0.045 13.7 0.0 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.24 CBZ37228.1 - 0.0051 16.1 0.6 0.013 14.8 0.1 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 CBZ37228.1 - 0.006 16.6 4.9 0.23 11.5 0.1 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CBZ37228.1 - 0.012 15.9 3.2 3.4 7.9 0.0 2.9 3 0 0 3 3 2 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 CBZ37228.1 - 0.018 14.3 0.5 0.039 13.2 0.1 1.7 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 CBZ37228.1 - 0.028 13.7 1.5 0.033 13.5 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 CBZ37228.1 - 0.031 14.5 0.1 2.4 8.3 0.0 3.0 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 CBZ37228.1 - 0.038 13.3 0.1 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CBZ37228.1 - 0.074 13.6 0.2 15 6.2 0.0 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.14 CBZ37228.1 - 0.12 12.0 0.2 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4404 PF14357.6 CBZ37230.1 - 0.13 12.9 1.8 0.4 11.3 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TipAS PF07739.13 CBZ37230.1 - 0.24 12.0 0.7 1.7 9.2 0.1 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Sulfotransfer_4 PF17784.1 CBZ37231.1 - 1e-46 159.5 0.0 1.7e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Pol_alpha_B_N PF08418.10 CBZ37232.1 - 6.8 6.6 9.7 4.6 7.1 4.4 2.4 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal FAM104 PF15434.6 CBZ37232.1 - 8.5 7.0 6.9 5.4 7.6 0.6 2.9 3 0 0 3 3 3 0 Family 104 zf-Tim10_DDP PF02953.15 CBZ37234.1 - 0.0019 17.8 1.0 0.1 12.2 0.2 2.4 2 0 0 2 2 2 2 Tim10/DDP family zinc finger DnaJ PF00226.31 CBZ37235.1 - 7.8e-23 80.4 0.5 1.2e-22 79.7 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain Zip PF02535.22 CBZ37235.1 - 0.023 13.9 1.2 0.043 13.0 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter DUF5100 PF17029.5 CBZ37236.1 - 0.036 13.9 0.0 0.047 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) Bacteriocin_IIc PF10439.9 CBZ37236.1 - 0.2 11.8 0.1 0.3 11.2 0.1 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Ribosomal_S3_C PF00189.20 CBZ37237.1 - 3.4e-19 69.1 1.8 3.4e-19 69.1 1.8 2.0 2 1 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CBZ37237.1 - 2.8e-07 30.3 0.2 6.1e-07 29.2 0.2 1.5 1 0 0 1 1 1 1 KH domain FIBP PF05427.11 CBZ37240.1 - 1.9e-07 30.7 0.0 0.0018 17.7 0.0 3.0 3 0 0 3 3 3 2 Acidic fibroblast growth factor binding (FIBP) WD40 PF00400.32 CBZ37241.1 - 2.2e-07 31.5 2.0 0.13 13.1 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37241.1 - 3.6e-06 27.2 0.0 0.94 9.8 0.0 4.8 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain NAPRTase PF04095.16 CBZ37242.1 - 1.1e-71 241.3 0.0 1.4e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CBZ37242.1 - 3.5e-40 137.3 0.1 7.9e-40 136.1 0.1 1.6 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain SAM_2 PF07647.17 CBZ37242.1 - 0.1 12.7 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Skp1 PF01466.19 CBZ37244.1 - 0.00041 20.4 0.1 0.00069 19.7 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Rhodanese PF00581.20 CBZ37245.1 - 8.3e-09 35.9 0.0 1.1e-08 35.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF1611 PF07755.11 CBZ37245.1 - 0.051 12.9 0.1 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain ORF_12_N PF18042.1 CBZ37245.1 - 0.095 13.1 0.1 0.2 12.1 0.0 1.6 1 1 0 1 1 1 0 ORF 12 gene product N-terminal DAGAT PF03982.13 CBZ37246.1 - 2.7e-19 69.2 0.1 6.5e-12 45.0 0.0 4.2 4 0 0 4 4 4 3 Diacylglycerol acyltransferase Cation_ATPase_C PF00689.21 CBZ37247.1 - 1e-39 136.1 4.5 1e-39 136.1 4.5 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CBZ37247.1 - 1.4e-30 106.2 2.0 1.4e-30 106.2 2.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CBZ37247.1 - 7.8e-10 39.4 0.0 0.11 12.8 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ37247.1 - 2e-07 31.0 0.0 4.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBZ37247.1 - 9e-07 28.5 0.0 2.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBZ37247.1 - 8.8e-05 22.4 0.2 0.00015 21.6 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1774 PF08611.10 CBZ37247.1 - 2.7 8.4 6.0 1.6 9.1 0.1 3.1 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) PSP1 PF04468.12 CBZ37248.1 - 6.1e-13 48.9 0.1 1.5e-12 47.6 0.1 1.6 1 1 0 1 1 1 1 PSP1 C-terminal conserved region PPTA PF01239.22 CBZ37249.1 - 7.4e-27 92.3 19.3 2.6e-08 33.3 0.6 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Thioredoxin_14 PF18402.1 CBZ37249.1 - 0.037 14.0 0.2 0.063 13.2 0.2 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Phage_sheath_1 PF04984.14 CBZ37249.1 - 0.047 13.6 0.8 1.5 8.7 0.2 2.5 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain OCRE PF17780.1 CBZ37250.1 - 0.0038 17.2 6.6 0.0057 16.6 6.6 1.3 1 0 0 1 1 1 1 OCRE domain TPR_MLP1_2 PF07926.12 CBZ37251.1 - 2 8.5 9.9 0.15 12.2 3.6 2.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Voltage_CLC PF00654.20 CBZ37253.1 - 1.6e-97 326.9 29.2 2.3e-96 323.1 25.9 2.2 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 CBZ37253.1 - 5.8e-11 42.7 0.2 6.2e-06 26.6 0.1 2.5 2 0 0 2 2 2 2 CBS domain Gly-zipper_YMGG PF13441.6 CBZ37253.1 - 0.81 9.5 4.8 15 5.4 0.0 2.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper YEATS PF03366.16 CBZ37255.1 - 1.4e-08 34.6 0.0 2.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 YEATS family PSK_trans_fac PF07704.11 CBZ37255.1 - 2 9.2 9.5 1.3 9.8 1.8 2.7 3 0 0 3 3 3 0 Rv0623-like transcription factor Guanylate_kin PF00625.21 CBZ37256.1 - 1.2e-47 162.0 0.0 1.4e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 CBZ37256.1 - 3e-06 27.8 0.1 6.4e-06 26.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBZ37256.1 - 8.2e-06 25.9 0.0 1.3e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CBZ37256.1 - 5.9e-05 23.3 0.3 0.00045 20.4 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ37256.1 - 0.00054 20.2 0.0 0.0028 17.9 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ37256.1 - 0.002 18.5 0.2 0.0029 18.0 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ37256.1 - 0.0026 17.7 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_17 PF13207.6 CBZ37256.1 - 0.0026 18.2 0.2 0.36 11.3 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 CBZ37256.1 - 0.018 15.1 0.1 0.081 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) dNK PF01712.19 CBZ37256.1 - 0.02 14.8 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Rad17 PF03215.15 CBZ37256.1 - 0.036 14.0 0.0 0.056 13.4 0.0 1.4 1 1 0 1 1 1 0 Rad17 P-loop domain ADK PF00406.22 CBZ37256.1 - 0.072 13.2 0.3 4 7.5 0.1 2.3 2 0 0 2 2 2 0 Adenylate kinase ABC_tran PF00005.27 CBZ37256.1 - 0.12 12.9 0.1 0.18 12.3 0.1 1.8 1 1 0 1 1 1 0 ABC transporter zf-CW PF07496.15 CBZ37257.1 - 3.1e-14 52.7 13.8 8.4e-10 38.5 5.7 3.8 3 0 0 3 3 3 3 CW-type Zinc Finger Yippee-Mis18 PF03226.14 CBZ37258.1 - 0.00074 19.7 1.6 0.79 10.0 0.2 2.6 2 0 0 2 2 2 2 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nup88 PF10168.9 CBZ37258.1 - 0.18 9.6 11.6 0.25 9.1 11.6 1.1 1 0 0 1 1 1 0 Nuclear pore component DUF16 PF01519.16 CBZ37258.1 - 6 7.4 14.2 37 4.9 14.2 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.12 CBZ37258.1 - 8.5 7.1 19.6 1.1 9.9 2.9 3.4 2 1 1 3 3 3 0 SlyX Big_3_4 PF13754.6 CBZ37262.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function PUF PF00806.19 CBZ37263.1 - 2e-50 165.7 6.3 5.4e-06 25.8 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ax_dynein_light PF10211.9 CBZ37267.1 - 1.2e-44 152.5 11.8 1.5e-44 152.2 11.8 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain RSRP PF17069.5 CBZ37267.1 - 0.16 11.5 2.4 0.25 10.9 2.4 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 TRAP-gamma PF07074.12 CBZ37267.1 - 1.2 8.6 2.8 2 8.0 2.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) APG6_N PF17675.1 CBZ37267.1 - 6.4 7.3 19.7 0.78 10.3 15.6 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region AAA PF00004.29 CBZ37269.1 - 2.1e-14 54.0 0.0 8.6e-10 39.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ37269.1 - 1.6e-05 25.0 0.0 4.8e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ37269.1 - 5.8e-05 23.5 2.3 0.00016 22.1 0.2 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CBZ37269.1 - 0.0017 18.6 0.0 0.013 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ37269.1 - 0.0026 17.9 0.0 0.0096 16.1 0.0 1.9 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CBZ37269.1 - 0.0028 17.4 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CBZ37269.1 - 0.0031 18.1 0.7 0.014 16.0 0.1 2.6 2 2 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CBZ37269.1 - 0.0046 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBZ37269.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBZ37269.1 - 0.0081 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 CBZ37269.1 - 0.029 13.7 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 KaiC IPT PF01745.16 CBZ37269.1 - 0.04 13.3 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Isopentenyl transferase DUF815 PF05673.13 CBZ37269.1 - 0.043 13.0 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 CBZ37269.1 - 0.044 14.2 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Mg_chelatase PF01078.21 CBZ37269.1 - 0.045 13.1 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CBZ37269.1 - 0.046 12.9 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 CBZ37269.1 - 0.05 13.3 0.3 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CBZ37269.1 - 0.062 13.5 0.3 0.18 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 CBZ37269.1 - 0.077 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CBZ37269.1 - 0.079 13.3 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ37269.1 - 0.08 12.8 0.0 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 CBZ37269.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 CBZ37269.1 - 0.14 11.3 0.0 0.44 9.7 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_11 PF13086.6 CBZ37269.1 - 0.21 11.4 1.7 0.67 9.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain PPR_2 PF13041.6 CBZ37270.1 - 4e-05 23.7 0.2 0.00025 21.2 0.1 2.3 3 0 0 3 3 3 1 PPR repeat family PPR PF01535.20 CBZ37270.1 - 0.00059 19.9 0.1 1.9 8.9 0.0 3.6 3 0 0 3 3 3 2 PPR repeat TPR_19 PF14559.6 CBZ37270.1 - 0.038 14.5 1.6 0.14 12.7 0.0 2.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.6 CBZ37270.1 - 0.039 14.0 0.0 0.096 12.8 0.0 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain F-box PF00646.33 CBZ37271.1 - 0.03 14.2 0.0 0.085 12.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain CDC45 PF02724.14 CBZ37271.1 - 0.092 11.0 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein GcrA PF07750.11 CBZ37271.1 - 0.23 11.9 2.2 0.34 11.3 0.2 2.2 2 0 0 2 2 2 0 GcrA cell cycle regulator Rrn6 PF10214.9 CBZ37271.1 - 0.42 9.1 7.9 0.73 8.3 7.9 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor F-box-like PF12937.7 CBZ37271.1 - 2.7 8.0 7.7 1.9 8.4 2.3 2.9 3 0 0 3 3 3 0 F-box-like WD40 PF00400.32 CBZ37272.1 - 6.6e-10 39.4 10.0 1.9e-06 28.5 0.0 5.5 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37272.1 - 7.5e-05 23.0 0.9 0.42 10.9 0.0 3.9 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CBZ37272.1 - 0.0035 17.4 0.1 12 5.9 0.1 4.5 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region SlyX PF04102.12 CBZ37272.1 - 0.034 14.8 0.4 0.88 10.2 0.1 2.6 2 0 0 2 2 2 0 SlyX PQQ_3 PF13570.6 CBZ37272.1 - 0.21 12.1 3.3 7.9 7.1 0.0 4.0 2 1 1 3 3 3 0 PQQ-like domain CENP-Q PF13094.6 CBZ37272.1 - 0.28 11.4 1.8 0.57 10.4 1.1 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit WD40 PF00400.32 CBZ37273.1 - 1.1e-08 35.6 8.1 0.00029 21.6 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37273.1 - 0.0037 17.5 0.0 28 5.1 0.0 3.6 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4226 PF10774.9 CBZ37273.1 - 1.3 9.4 6.9 8.4 6.7 1.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) Hepatitis_core PF00906.20 CBZ37274.1 - 0.7 9.4 7.1 1.3 8.5 7.1 1.4 1 0 0 1 1 1 0 Hepatitis core antigen CFC PF09443.10 CBZ37275.1 - 0.041 13.7 0.1 0.071 13.0 0.1 1.3 1 0 0 1 1 1 0 Cripto_Frl-1_Cryptic (CFC) Thioredoxin PF00085.20 CBZ37278.1 - 7.9e-09 35.4 0.1 1.3e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBZ37278.1 - 0.0041 17.4 0.4 0.076 13.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 CBZ37278.1 - 0.019 14.9 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_2 PF13098.6 CBZ37278.1 - 0.055 13.9 0.5 0.16 12.5 0.2 1.9 1 1 1 2 2 2 0 Thioredoxin-like domain Ribosomal_L29 PF00831.23 CBZ37278.1 - 0.23 11.5 2.3 7.5 6.6 0.1 2.5 2 0 0 2 2 2 0 Ribosomal L29 protein MFS_1_like PF12832.7 CBZ37279.1 - 2e-44 152.0 27.6 3.4e-44 151.2 27.6 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 CBZ37279.1 - 6e-16 58.3 47.5 1.2e-08 34.3 27.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 CBZ37279.1 - 1.1e-05 24.6 23.7 4.9e-05 22.5 23.7 2.1 1 1 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 CBZ37279.1 - 9.6e-05 21.3 3.5 9.6e-05 21.3 3.5 2.2 2 0 0 2 2 2 2 LacY proton/sugar symporter DiS_P_DiS PF06750.13 CBZ37279.1 - 0.068 13.3 0.5 0.24 11.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain ABC1 PF03109.16 CBZ37280.1 - 6.8e-29 100.4 0.0 1.4e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CBZ37280.1 - 0.011 15.3 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 CBZ37280.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain WaaY PF06176.11 CBZ37280.1 - 0.086 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DAD PF02109.16 CBZ37280.1 - 0.13 12.6 0.1 5.9 7.3 0.0 2.8 3 0 0 3 3 3 0 DAD family APH PF01636.23 CBZ37280.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family Cwf_Cwc_15 PF04889.12 CBZ37281.1 - 2.2e-05 24.3 8.9 3.7e-05 23.6 8.6 1.5 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 CBZ37281.1 - 0.16 10.6 10.8 0.17 10.5 10.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3381 PF11861.8 CBZ37281.1 - 0.46 10.3 5.1 0.23 11.3 3.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Ndc1_Nup PF09531.10 CBZ37281.1 - 1.3 7.7 6.3 1.5 7.4 6.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3246 PF11596.8 CBZ37281.1 - 3.5 7.0 7.2 6.5 6.1 7.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) Aminotran_1_2 PF00155.21 CBZ37284.1 - 1.3e-50 172.7 0.0 1.5e-50 172.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CBZ37284.1 - 6.4e-06 25.0 0.2 9.5e-06 24.4 0.2 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CBZ37284.1 - 1.9e-05 23.8 0.4 4e-05 22.7 0.4 1.4 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CBZ37284.1 - 5.6e-05 22.6 0.1 8.2e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CBZ37284.1 - 0.032 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF3341 PF11821.8 CBZ37284.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) RNase_Zc3h12a PF11977.8 CBZ37284.1 - 0.14 12.0 0.2 0.32 10.8 0.2 1.6 1 1 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain SNARE PF05739.19 CBZ37285.1 - 5.8e-07 29.4 0.1 5.8e-07 29.4 0.1 1.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CBZ37285.1 - 5.8e-07 29.4 13.0 8.9e-07 28.8 13.0 1.3 1 0 0 1 1 1 1 Syntaxin Ubiquitin_3 PF14836.6 CBZ37285.1 - 0.031 14.2 0.8 0.076 13.0 0.5 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain CagS PF16707.5 CBZ37285.1 - 0.1 12.6 1.5 0.12 12.4 0.4 1.6 2 0 0 2 2 2 0 Cag pathogenicity island protein S of Helicobacter pylori Syntaxin_2 PF14523.6 CBZ37285.1 - 3.8 7.9 11.8 0.99 9.8 4.4 2.3 2 0 0 2 2 2 0 Syntaxin-like protein UPF0113 PF03657.13 CBZ37286.1 - 9.6e-19 67.4 0.0 2.4e-18 66.1 0.0 1.7 2 0 0 2 2 2 1 UPF0113 PUA domain UPF0113_N PF17833.1 CBZ37286.1 - 4.7e-18 65.5 0.1 7.5e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain DUF5317 PF17248.2 CBZ37286.1 - 0.063 13.3 0.0 0.11 12.4 0.0 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5317) Clavanin PF05452.11 CBZ37286.1 - 0.075 13.2 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 Clavanin Complex1_LYR PF05347.15 CBZ37287.1 - 1.2e-07 31.6 2.8 2.1e-07 30.9 2.8 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF1416 PF07210.12 CBZ37287.1 - 0.083 12.8 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Pkinase PF00069.25 CBZ37290.1 - 4.2e-65 219.7 0.0 5.6e-65 219.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37290.1 - 4.8e-31 108.0 0.0 7.2e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CBZ37290.1 - 2e-05 24.0 0.4 3.6e-05 23.2 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ37290.1 - 0.00022 20.3 0.2 0.00034 19.7 0.2 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CBZ37290.1 - 0.0025 17.2 0.0 0.008 15.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ37290.1 - 0.005 15.7 1.2 0.0057 15.5 0.2 1.7 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CBZ37290.1 - 0.054 12.6 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 CBZ37290.1 - 0.077 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 MRP-L28 PF09812.9 CBZ37291.1 - 6.5e-05 23.1 0.2 0.00011 22.4 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Hist_deacetyl PF00850.19 CBZ37291.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Histone deacetylase domain Pkinase PF00069.25 CBZ37292.1 - 3e-49 167.8 0.0 5.7e-28 98.0 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37292.1 - 3.7e-29 101.8 0.1 2.4e-20 72.9 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase FHA PF00498.26 CBZ37292.1 - 9.7e-10 38.7 0.1 0.001 19.4 0.0 2.7 2 0 0 2 2 2 2 FHA domain Kinase-like PF14531.6 CBZ37292.1 - 4.5e-06 26.2 0.2 0.00074 18.9 0.1 2.2 2 0 0 2 2 2 2 Kinase-like Yop-YscD_cpl PF16697.5 CBZ37292.1 - 6.6e-05 23.2 0.0 0.00061 20.1 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain RIO1 PF01163.22 CBZ37292.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CBZ37292.1 - 0.0091 15.9 0.0 0.14 12.1 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family WD40 PF00400.32 CBZ37293.1 - 1.5e-14 54.1 19.8 0.00084 20.1 0.3 6.6 7 0 0 7 7 6 3 WD domain, G-beta repeat Nup160 PF11715.8 CBZ37293.1 - 0.00016 20.5 6.3 0.12 11.0 0.1 3.6 2 1 2 4 4 4 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 CBZ37293.1 - 0.039 14.5 0.0 0.33 11.5 0.0 2.5 2 0 0 2 2 2 0 PQQ-like domain OmpH PF03938.14 CBZ37293.1 - 0.064 13.6 26.3 0.32 11.3 13.5 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HOOK PF05622.12 CBZ37293.1 - 0.065 11.4 28.5 0.25 9.5 28.1 1.8 1 1 1 2 2 2 0 HOOK protein CALCOCO1 PF07888.11 CBZ37293.1 - 0.069 12.0 26.8 0.097 11.5 26.8 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IFP_35_N PF07334.13 CBZ37293.1 - 0.21 11.7 11.1 3.6 7.7 1.0 3.4 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus BLOC1_2 PF10046.9 CBZ37293.1 - 0.21 11.9 9.6 0.028 14.7 3.1 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CTP_transf_like PF01467.26 CBZ37293.1 - 0.49 10.6 3.8 0.71 10.1 1.3 2.3 1 1 0 2 2 2 0 Cytidylyltransferase-like NHL PF01436.21 CBZ37293.1 - 0.71 10.0 2.2 38 4.6 0.1 3.5 3 0 0 3 3 3 0 NHL repeat Cep57_MT_bd PF06657.13 CBZ37293.1 - 0.98 9.9 19.2 0.81 10.2 2.8 3.7 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF1192 PF06698.11 CBZ37293.1 - 1 9.5 6.7 0.22 11.6 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TPR_MLP1_2 PF07926.12 CBZ37293.1 - 1.1 9.3 28.3 0.41 10.7 15.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 CBZ37293.1 - 1.2 9.3 37.0 10 6.3 28.7 3.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1319 PF07028.11 CBZ37293.1 - 1.9 8.8 7.2 5.2 7.3 0.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) AAA_13 PF13166.6 CBZ37293.1 - 2.2 6.8 13.9 3.7 6.1 13.9 1.3 1 0 0 1 1 1 0 AAA domain FUSC PF04632.12 CBZ37293.1 - 3.4 6.1 19.7 5.2 5.5 19.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SLATT_fungal PF18142.1 CBZ37293.1 - 4.6 7.3 10.4 15 5.6 5.0 2.7 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain YabA PF06156.13 CBZ37293.1 - 8.6 7.1 20.6 3.2 8.5 1.1 3.3 1 1 2 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 CBZ37293.1 - 8.7 6.7 26.0 2.3 8.6 13.1 2.3 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 CBZ37293.1 - 9 6.4 8.7 7 6.7 2.6 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Aa_trans PF01490.18 CBZ37294.1 - 2e-52 178.3 18.7 2.4e-52 178.0 18.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ37294.1 - 1.2e-09 37.8 15.6 1.2e-09 37.8 15.6 2.8 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family TssN PF17555.2 CBZ37294.1 - 2.6 7.4 13.3 1.4 8.3 0.5 3.4 2 1 1 3 3 3 0 Type VI secretion system, TssN RRM_1 PF00076.22 CBZ37296.1 - 2.1e-08 33.9 0.0 6.5e-05 22.7 0.0 2.3 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CBZ37297.1 - 2.4e-13 49.7 0.1 1.7e-09 37.3 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ37297.1 - 0.00094 18.8 0.0 0.0021 17.7 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ37297.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 CBZ37298.1 - 1.4e-09 37.6 0.0 4.6e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ37298.1 - 0.0061 16.2 0.0 0.021 14.4 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 CBZ37298.1 - 0.011 15.7 0.1 0.042 13.9 0.0 2.0 2 0 0 2 2 2 0 RNA binding domain RRM_1 PF00076.22 CBZ37299.1 - 2.2e-16 59.4 0.0 3.7e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ37299.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif TPR_12 PF13424.6 CBZ37300.1 - 3.9e-06 27.1 20.5 4.1e-05 23.8 1.5 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ37300.1 - 0.039 14.0 2.4 7.7 6.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ37300.1 - 0.23 11.4 12.0 20 5.2 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ37300.1 - 0.35 11.4 5.2 5.9 7.5 0.9 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ37300.1 - 0.99 10.4 13.5 4.2 8.5 0.3 7.4 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ37300.1 - 9.5 6.6 18.1 7.2 7.0 0.0 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat ubiquitin PF00240.23 CBZ37301.1 - 9e-05 22.2 0.0 0.67 9.8 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin family TetR_C_28 PF17937.1 CBZ37301.1 - 1.6 9.2 5.0 5.4 7.5 0.9 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain TPR_14 PF13428.6 CBZ37302.1 - 0.18 12.7 0.0 0.18 12.7 0.0 6.0 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ37302.1 - 1.6 9.6 0.0 1.6 9.6 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat PRA1 PF03208.19 CBZ37303.1 - 1.1e-18 67.2 3.1 1.1e-18 67.2 3.1 1.4 2 0 0 2 2 2 1 PRA1 family protein UbiA PF01040.18 CBZ37303.1 - 0.015 14.6 4.8 0.023 14.0 4.3 1.5 1 1 0 1 1 1 0 UbiA prenyltransferase family DUF2070 PF09843.9 CBZ37303.1 - 0.35 9.1 4.8 0.44 8.8 4.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FixQ PF05545.11 CBZ37303.1 - 0.74 9.8 0.0 0.74 9.8 0.0 2.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ PRA1 PF03208.19 CBZ37304.1 - 7.8e-27 93.7 8.2 1.2e-26 93.1 8.2 1.2 1 0 0 1 1 1 1 PRA1 family protein FA_hydroxylase PF04116.13 CBZ37304.1 - 0.92 9.8 4.7 3.5 8.0 0.1 2.3 2 1 0 2 2 2 0 Fatty acid hydroxylase superfamily GST_C PF00043.25 CBZ37306.1 - 4.5e-14 52.4 0.0 7.3e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBZ37306.1 - 1e-07 32.1 0.1 1.7e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CBZ37306.1 - 2.1e-07 31.2 0.0 3.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CBZ37306.1 - 3.3e-06 27.0 0.0 7.3e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CBZ37306.1 - 0.035 14.5 0.0 0.081 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TauE PF01925.19 CBZ37308.1 - 3.8e-15 56.2 13.6 9.7e-09 35.2 5.7 2.4 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE DUF3021 PF11457.8 CBZ37308.1 - 0.00025 21.4 1.3 0.00025 21.4 1.3 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3021) DivIC PF04977.15 CBZ37308.1 - 0.0049 16.6 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Septum formation initiator RseC_MucC PF04246.12 CBZ37308.1 - 0.0078 16.2 4.2 0.13 12.2 0.4 2.8 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC DUF2244 PF10003.9 CBZ37308.1 - 0.044 13.5 0.2 0.044 13.5 0.2 2.7 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) CcmD PF04995.14 CBZ37308.1 - 0.077 13.1 0.3 9 6.5 0.0 3.0 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF3611 PF12263.8 CBZ37308.1 - 0.16 11.9 6.4 0.21 11.4 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) MscS_TM PF12794.7 CBZ37308.1 - 1.1 8.1 7.5 0.082 11.7 0.2 2.4 2 1 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Ribul_P_3_epim PF00834.19 CBZ37309.1 - 1.6e-58 197.4 0.0 1.9e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 CBZ37309.1 - 0.00087 18.9 0.1 0.0036 16.9 0.1 1.9 2 1 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family adh_short PF00106.25 CBZ37309.1 - 0.089 12.2 0.4 0.28 10.6 0.2 1.8 2 0 0 2 2 2 0 short chain dehydrogenase adh_short PF00106.25 CBZ37312.1 - 6.6e-33 113.8 0.0 8.4e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ37312.1 - 1.1e-22 80.8 0.0 1.5e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ37312.1 - 1.3e-07 31.7 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CBZ37312.1 - 0.038 13.9 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 CBZ37312.1 - 0.048 13.1 0.1 0.078 12.4 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TruD PF01142.18 CBZ37313.1 - 0.17 10.7 0.0 0.56 9.0 0.0 1.8 2 0 0 2 2 2 0 tRNA pseudouridine synthase D (TruD) Staph_haemo PF05480.11 CBZ37313.1 - 0.19 11.5 0.2 0.44 10.4 0.2 1.6 1 0 0 1 1 1 0 Staphylococcus haemolytic protein AAA_lid_4 PF17864.1 CBZ37313.1 - 0.95 9.3 0.0 0.95 9.3 0.0 2.9 3 0 0 3 3 3 0 RuvB AAA lid domain Peptidase_M20 PF01546.28 CBZ37314.1 - 1.6e-18 67.1 0.0 2.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CBZ37314.1 - 2.7e-09 36.9 0.0 4.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain HEAT PF02985.22 CBZ37315.1 - 4.4e-07 29.6 20.5 8.1 7.0 0.0 9.8 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 CBZ37315.1 - 0.00014 22.2 4.1 0.72 10.3 0.1 5.4 5 2 1 6 6 6 2 HEAT repeats Cnd1 PF12717.7 CBZ37315.1 - 0.0054 16.8 12.1 1.5 8.9 0.0 5.1 7 0 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CBZ37315.1 - 0.012 16.1 4.9 1.1 10.0 0.2 4.6 5 1 0 5 5 5 0 Vacuolar 14 Fab1-binding region Nipped-B_C PF12830.7 CBZ37315.1 - 0.16 11.9 0.6 90 2.9 0.0 3.4 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Pro_isomerase PF00160.21 CBZ37316.1 - 7.4e-45 153.1 0.0 9e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YfkB PF08756.10 CBZ37317.1 - 0.032 14.0 0.0 0.039 13.7 0.0 1.2 1 0 0 1 1 1 0 YfkB-like domain PHM7_cyt PF14703.6 CBZ37317.1 - 0.045 14.0 0.4 0.054 13.7 0.4 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter PIGA PF08288.12 CBZ37320.1 - 3.1e-38 130.2 0.1 6.8e-38 129.1 0.1 1.6 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CBZ37320.1 - 8.2e-28 97.5 0.3 1.4e-27 96.8 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CBZ37320.1 - 3.1e-27 95.2 0.0 4.7e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ37320.1 - 1.3e-22 80.7 0.0 2e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CBZ37320.1 - 4e-13 50.1 0.0 7.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CBZ37320.1 - 0.0012 18.9 0.0 0.011 15.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CBZ37320.1 - 0.036 14.4 0.0 0.097 13.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 ThiI PF02568.14 CBZ37321.1 - 1.8e-45 155.0 0.2 3.1e-45 154.2 0.2 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Aminotran_5 PF00266.19 CBZ37321.1 - 4e-27 95.1 0.2 8.5e-13 48.0 0.0 2.3 1 1 1 2 2 2 2 Aminotransferase class-V tRNA_Me_trans PF03054.16 CBZ37321.1 - 6.1e-05 22.0 0.1 0.00012 21.0 0.1 1.5 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 CBZ37321.1 - 0.0022 17.5 0.2 0.026 14.0 0.0 2.5 3 0 0 3 3 3 1 Queuosine biosynthesis protein QueC DNA_pol_B PF00136.21 CBZ37322.1 - 6.5e-138 460.3 0.0 9e-138 459.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CBZ37322.1 - 2.5e-74 250.4 0.0 4.1e-74 249.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CBZ37322.1 - 2.5e-17 63.1 8.5 5.7e-17 61.9 8.5 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta zinc-ribbons_6 PF07191.12 CBZ37322.1 - 0.035 14.1 5.7 0.44 10.6 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbons DNA_pol_B_2 PF03175.13 CBZ37322.1 - 0.06 12.2 0.1 0.66 8.8 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral zf-RING-like PF08746.11 CBZ37322.1 - 4 7.8 8.3 6.8 7.1 1.5 2.9 2 0 0 2 2 2 0 RING-like domain SNF2_N PF00176.23 CBZ37323.1 - 9.1e-71 238.4 0.6 1e-69 234.9 0.1 2.7 2 1 1 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ37323.1 - 3.1e-20 72.6 0.0 4.7e-19 68.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ37323.1 - 1.4e-08 34.9 0.0 5.1e-08 33.1 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 CBZ37323.1 - 1.5e-07 31.4 0.6 4.4e-07 29.9 0.6 1.8 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 CBZ37323.1 - 2.4e-07 31.5 8.8 8.9e-07 29.7 8.8 2.0 1 0 0 1 1 1 1 HAND DEAD PF00270.29 CBZ37323.1 - 0.00093 19.0 0.0 0.0042 16.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 CBZ37323.1 - 0.035 13.3 0.0 0.1 11.8 0.0 1.7 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 RRM_occluded PF16842.5 CBZ37323.1 - 0.042 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif RXT2_N PF08595.11 CBZ37323.1 - 8.3 6.4 8.2 18 5.3 4.0 3.1 3 0 0 3 3 3 0 RXT2-like, N-terminal Pkinase PF00069.25 CBZ37324.1 - 1.3e-67 228.0 0.0 5.2e-67 226.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37324.1 - 8.3e-40 136.7 0.0 1.4e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 CBZ37324.1 - 5.4e-15 55.6 1.1 1.7e-08 34.8 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ37324.1 - 3.2e-10 38.8 1.7 0.082 12.5 0.1 4.3 4 0 0 4 4 4 3 EF hand Kinase-like PF14531.6 CBZ37324.1 - 3.7e-10 39.6 0.0 1.2e-09 37.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like EF-hand_6 PF13405.6 CBZ37324.1 - 4.5e-10 38.6 1.3 0.037 13.9 0.0 5.5 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CBZ37324.1 - 5.8e-07 29.3 2.1 0.007 16.2 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair RIO1 PF01163.22 CBZ37324.1 - 2.3e-05 24.1 1.3 4.7e-05 23.1 1.3 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CBZ37324.1 - 0.00063 18.8 0.1 0.00096 18.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CBZ37324.1 - 0.0021 17.4 0.2 0.004 16.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CBZ37324.1 - 0.0067 16.0 0.3 0.013 15.0 0.3 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL EF-hand_5 PF13202.6 CBZ37324.1 - 0.024 14.1 0.6 27 4.5 0.0 3.9 3 0 0 3 3 3 0 EF hand MYO10_CC PF16735.5 CBZ37324.1 - 0.13 12.4 0.2 0.37 10.9 0.2 1.8 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain Crystallin PF00525.18 CBZ37324.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal TPR_12 PF13424.6 CBZ37325.1 - 2.8e-18 66.0 12.0 1.6e-08 34.7 1.4 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ37325.1 - 4.4e-12 45.3 7.0 0.11 12.4 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ37325.1 - 4.7e-09 35.7 9.9 0.52 10.5 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat ANAPC5 PF12862.7 CBZ37325.1 - 1.3e-05 25.2 4.2 0.0057 16.7 0.1 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 CBZ37325.1 - 8.1e-05 22.5 4.7 1.7 9.1 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ37325.1 - 0.00075 19.4 7.3 25 5.2 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CBZ37325.1 - 0.0011 18.4 4.1 0.0015 18.0 2.7 1.8 2 0 0 2 2 2 1 MalT-like TPR region TPR_9 PF13371.6 CBZ37325.1 - 0.0055 16.8 2.7 0.85 9.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 CBZ37325.1 - 0.033 13.9 0.2 3.1 7.5 0.0 2.6 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_21 PF09976.9 CBZ37325.1 - 0.04 13.6 0.2 0.087 12.5 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain MIF PF01187.18 CBZ37327.1 - 1.5e-11 44.6 0.0 1.6e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.21 CBZ37327.1 - 0.046 13.6 0.0 2.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme MIF PF01187.18 CBZ37328.1 - 5.8e-09 36.3 0.0 6.2e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Topo_C_assoc PF14370.6 CBZ37328.1 - 0.0084 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal topoisomerase domain OTT_1508_deam PF14441.6 CBZ37329.1 - 0.0018 18.3 1.2 0.0028 17.6 0.1 1.9 2 0 0 2 2 2 1 OTT_1508-like deaminase LisH PF08513.11 CBZ37331.1 - 0.002 18.0 0.6 0.008 16.1 0.1 2.3 2 0 0 2 2 2 1 LisH DOT1 PF08123.13 CBZ37332.1 - 5.1e-15 55.6 0.1 7.2e-15 55.1 0.1 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 CBZ37332.1 - 0.00026 20.8 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CBZ37332.1 - 0.015 14.8 0.2 0.13 11.7 0.0 2.1 1 1 1 2 2 2 0 Putative methyltransferase Methyltransf_25 PF13649.6 CBZ37332.1 - 0.031 15.0 0.0 0.05 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ37332.1 - 0.04 13.8 0.0 0.1 12.4 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ37332.1 - 0.05 14.3 0.0 0.095 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ37332.1 - 0.13 13.0 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 CBZ37332.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DER1 PF04511.15 CBZ37333.1 - 1.9e-31 109.5 11.7 2.3e-31 109.2 11.7 1.0 1 0 0 1 1 1 1 Der1-like family Oleosin PF01277.17 CBZ37333.1 - 0.003 17.3 0.8 0.003 17.3 0.8 2.0 2 1 1 3 3 3 1 Oleosin DUF373 PF04123.13 CBZ37333.1 - 2.2 7.7 6.6 6.3 6.1 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Pkinase PF00069.25 CBZ37336.1 - 1.2e-48 165.8 0.0 1.5e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37336.1 - 4.7e-25 88.4 0.0 6.9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ37336.1 - 7.5e-05 22.8 0.1 0.00063 19.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CBZ37336.1 - 0.041 12.9 0.1 0.065 12.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CBZ37336.1 - 0.15 11.6 0.1 0.67 9.5 0.1 1.8 1 1 1 2 2 2 0 RIO1 family ABC1 PF03109.16 CBZ37336.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 ABC1 family Ras PF00071.22 CBZ37337.1 - 3.2e-50 169.9 0.0 3.8e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ37337.1 - 7.7e-34 116.5 0.0 1.2e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ37337.1 - 6.7e-16 58.2 0.0 8e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CBZ37337.1 - 1.1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ37337.1 - 1.3e-05 25.2 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ37337.1 - 1.8e-05 24.7 0.3 0.0041 17.0 0.4 2.8 2 1 1 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 CBZ37337.1 - 0.0023 18.4 0.1 0.005 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 CBZ37337.1 - 0.0028 17.4 0.2 0.054 13.2 0.2 2.3 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 CBZ37337.1 - 0.0083 15.7 0.0 0.06 12.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DAP3 PF10236.9 CBZ37337.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 ATP_bind_1 PF03029.17 CBZ37337.1 - 0.012 15.4 0.3 0.042 13.6 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 CBZ37337.1 - 0.015 14.8 0.1 0.046 13.2 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM PF00493.23 CBZ37337.1 - 0.016 14.3 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_29 PF13555.6 CBZ37337.1 - 0.017 14.8 1.2 0.049 13.4 1.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CBZ37337.1 - 0.019 14.6 0.5 1.6 8.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.10 CBZ37337.1 - 0.027 13.9 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CBZ37337.1 - 0.077 12.1 0.7 1.8 7.7 0.2 2.3 1 1 1 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 CBZ37337.1 - 0.078 13.5 1.1 0.14 12.6 0.4 1.7 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 CBZ37337.1 - 0.087 13.3 0.3 0.11 12.9 0.3 1.4 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 CBZ37337.1 - 0.091 11.9 0.2 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 CBZ37337.1 - 0.12 12.7 0.1 0.57 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CBZ37337.1 - 0.17 11.9 0.1 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 CBZ37337.1 - 0.19 11.0 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 Septin ABC_membrane_2 PF06472.15 CBZ37339.1 - 1.8e-64 217.8 0.2 2.6e-64 217.3 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CBZ37339.1 - 1.7e-18 67.5 0.0 3.1e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBZ37339.1 - 0.0028 17.5 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CBZ37339.1 - 0.0051 16.3 0.1 0.25 10.7 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CBZ37339.1 - 0.013 15.2 0.2 0.033 13.9 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3584 PF12128.8 CBZ37339.1 - 0.018 12.6 0.5 0.027 12.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_23 PF13476.6 CBZ37339.1 - 0.024 15.1 0.1 0.044 14.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ37339.1 - 0.033 14.1 0.1 0.32 10.9 0.0 2.6 3 0 0 3 3 3 0 NACHT domain AAA_30 PF13604.6 CBZ37339.1 - 0.039 13.7 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CBZ37339.1 - 0.069 12.5 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 CBZ37339.1 - 0.072 12.5 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DLIC PF05783.11 CBZ37339.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 CBZ37339.1 - 0.17 12.2 0.7 2.9 8.1 0.1 3.1 4 0 0 4 4 4 0 AAA domain NOG1_N PF17835.1 CBZ37340.1 - 2e-53 180.6 0.3 3.9e-53 179.7 0.3 1.5 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 CBZ37340.1 - 1.9e-27 94.8 0.0 4.6e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 CBZ37340.1 - 7.5e-23 80.3 6.3 2.1e-22 78.8 6.3 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 CBZ37340.1 - 2.8e-17 62.8 0.0 6.4e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ37340.1 - 4e-09 36.2 0.0 9.6e-09 35.0 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ37340.1 - 0.0015 18.5 0.0 1.5 8.7 0.0 2.7 2 1 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CBZ37340.1 - 0.007 15.7 0.1 0.023 14.0 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.23 CBZ37340.1 - 0.069 13.2 0.1 6.2 6.8 0.0 2.7 1 1 1 2 2 2 0 Dynamin family IQ PF00612.27 CBZ37341.1 - 0.00026 20.5 0.1 0.00078 19.0 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif FOP_dimer PF09398.10 CBZ37343.1 - 7.3e-12 45.4 0.0 1.3e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 CBZ37343.1 - 1.6e-05 23.8 0.0 2.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 LisH LisH PF08513.11 CBZ37343.1 - 0.012 15.6 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 0 LisH Snf7 PF03357.21 CBZ37344.1 - 9.6e-13 48.1 9.1 9.6e-13 48.1 9.1 2.0 1 1 1 2 2 2 1 Snf7 E3_binding PF02817.17 CBZ37344.1 - 0.064 13.6 0.2 0.16 12.4 0.2 1.7 1 1 0 1 1 1 0 e3 binding domain DUF1463 PF07316.11 CBZ37344.1 - 0.069 13.0 1.1 0.68 9.8 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1463) CAF1C_H4-bd PF12265.8 CBZ37345.1 - 6.3e-12 45.6 0.1 1.5e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF2992 PF11208.8 CBZ37345.1 - 0.062 13.5 3.3 0.58 10.4 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2992) WD40 PF00400.32 CBZ37345.1 - 0.18 12.7 9.4 0.22 12.5 0.0 4.8 6 0 0 6 6 6 0 WD domain, G-beta repeat Nop14 PF04147.12 CBZ37345.1 - 0.33 9.1 25.8 0.32 9.1 18.9 2.0 2 0 0 2 2 2 0 Nop14-like family Pho88 PF10032.9 CBZ37346.1 - 1.3e-25 89.7 0.0 1.6e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pribosyltran_N PF13793.6 CBZ37347.1 - 2.1e-40 137.3 0.1 1.2e-39 134.9 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBZ37347.1 - 1.5e-22 80.5 0.8 1.1e-21 77.7 0.2 2.1 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBZ37347.1 - 3.9e-18 65.5 0.1 8.3e-18 64.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBZ37347.1 - 0.0067 15.9 0.1 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase HHH_3 PF12836.7 CBZ37347.1 - 0.12 12.7 0.1 9.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif zn-ribbon_14 PF16503.5 CBZ37347.1 - 0.12 11.9 0.4 0.31 10.6 0.4 1.7 1 0 0 1 1 1 0 Zinc-ribbon PRORP PF16953.5 CBZ37349.1 - 7.7e-16 58.3 0.3 7.5e-12 45.3 0.1 4.4 4 1 0 4 4 4 1 Protein-only RNase P PPR_long PF17177.4 CBZ37349.1 - 5.6e-11 42.2 0.1 9.6e-11 41.4 0.1 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Ribosomal_L37e PF01907.19 CBZ37350.1 - 6.6e-25 87.0 8.5 1e-24 86.4 8.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e Pkinase PF00069.25 CBZ37353.1 - 1.9e-61 207.8 0.0 2.6e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37353.1 - 3.6e-39 134.6 0.1 4.8e-39 134.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBZ37353.1 - 4.1e-09 36.9 0.0 3.7e-08 33.8 0.0 2.3 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 CBZ37353.1 - 5.6e-08 32.5 0.0 7.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 CBZ37353.1 - 0.00043 20.7 0.1 0.0018 18.7 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 CBZ37353.1 - 0.0016 18.8 0.1 0.075 13.4 0.1 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 CBZ37353.1 - 0.033 13.0 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF1636 PF07845.11 CBZ37353.1 - 0.039 14.4 0.2 0.12 12.8 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1636) PH_3 PF14593.6 CBZ37353.1 - 0.069 13.3 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 PH domain PEN-2 PF10251.9 CBZ37355.1 - 6.9e-08 32.8 7.7 1.1e-07 32.2 7.7 1.4 1 1 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase Peptidase_C2 PF00648.21 CBZ37356.1 - 2.9e-34 118.4 0.0 4.7e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CBZ37356.1 - 1.3e-09 38.4 0.0 0.00025 21.3 0.0 3.6 3 0 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.18 CBZ37356.1 - 2e-08 34.2 0.2 6e-08 32.6 0.2 1.8 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Arm PF00514.23 CBZ37358.1 - 2.9e-05 23.9 3.5 2.5 8.3 0.0 5.1 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Nup84_Nup100 PF04121.13 CBZ37359.1 - 1.8e-07 29.7 0.0 0.0055 14.9 0.0 2.6 2 1 1 3 3 3 2 Nuclear pore protein 84 / 107 TAF4 PF05236.14 CBZ37359.1 - 0.11 12.2 0.4 0.27 10.9 0.4 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF383 PF04063.14 CBZ37360.1 - 0.0012 18.5 0.0 0.0072 16.0 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF383) HEAT PF02985.22 CBZ37360.1 - 0.034 14.4 1.4 5.6 7.5 0.0 4.2 5 0 0 5 5 5 0 HEAT repeat HrpB1_HrpK PF09613.10 CBZ37360.1 - 0.61 9.7 4.0 8.7 6.0 0.0 2.9 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Orf78 PF06024.12 CBZ37361.1 - 0.07 13.4 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Pkinase PF00069.25 CBZ37362.1 - 5.6e-46 157.0 0.0 1.8e-35 122.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37362.1 - 1.3e-27 96.7 0.1 5.6e-19 68.4 0.1 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase E1-E2_ATPase PF00122.20 CBZ37364.1 - 4.8e-47 159.8 0.7 1.1e-46 158.6 0.7 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 CBZ37364.1 - 8.2e-36 122.3 7.3 2.7e-15 56.6 0.1 3.9 4 0 0 4 4 4 3 Heavy-metal-associated domain Hydrolase PF00702.26 CBZ37364.1 - 4.6e-35 121.8 1.1 4.6e-35 121.8 1.1 2.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBZ37364.1 - 1e-06 28.7 0.2 1.1e-05 25.4 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ37364.1 - 0.0008 19.9 0.2 0.002 18.6 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CoA_binding_2 PF13380.6 CBZ37364.1 - 0.0023 18.4 0.5 0.017 15.6 0.5 2.5 1 0 0 1 1 1 1 CoA binding domain ProQ_C PF17516.2 CBZ37364.1 - 0.068 12.6 0.6 0.4 10.1 0.1 2.6 2 0 0 2 2 2 0 ProQ C-terminal domain cpYpsA PF12694.7 CBZ37364.1 - 0.094 12.5 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Circularly permutated YpsA SLOG family K_channel_TID PF07941.11 CBZ37364.1 - 1.8 9.1 5.1 6.6 7.3 5.1 2.0 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain His_Phos_1 PF00300.22 CBZ37365.1 - 6.5e-30 104.3 0.1 2.4e-21 76.3 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Sporozoite_P67 PF05642.11 CBZ37365.1 - 1 7.3 11.5 1.3 7.0 5.1 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen His_Phos_1 PF00300.22 CBZ37366.1 - 1e-17 64.5 0.0 1.9e-09 37.5 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) zf-HIT PF04438.16 CBZ37367.1 - 1.1e-06 28.4 12.0 2.1e-06 27.5 12.0 1.5 1 0 0 1 1 1 1 HIT zinc finger CwsA PF10814.8 CBZ37367.1 - 0.00043 20.5 4.4 0.00072 19.7 4.4 1.3 1 0 0 1 1 1 1 Cell wall synthesis protein CwsA STI1 PF17830.1 CBZ37367.1 - 0.09 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 STI1 domain zf-MYND PF01753.18 CBZ37367.1 - 0.19 11.8 12.6 0.38 10.9 12.6 1.5 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.24 CBZ37367.1 - 0.54 10.5 5.6 1 9.6 5.6 1.5 1 0 0 1 1 1 0 B-box zinc finger Kinesin PF00225.23 CBZ37369.1 - 6e-81 271.9 0.0 1.2e-80 271.0 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ37369.1 - 3.4e-23 82.2 0.0 7.7e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding NodZ PF05830.11 CBZ37369.1 - 0.039 12.8 0.0 0.096 11.5 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) Peptidase_S49_N PF08496.10 CBZ37369.1 - 0.27 11.3 3.3 12 5.9 0.2 2.7 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Dynein_heavy PF03028.15 CBZ37370.1 - 3.5e-05 23.9 0.0 7.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain WD40 PF00400.32 CBZ37370.1 - 0.048 14.6 16.9 6.8 7.7 0.4 6.5 8 0 0 8 8 8 0 WD domain, G-beta repeat Acid_PPase PF12689.7 CBZ37371.1 - 7.3e-50 169.1 0.0 8.3e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Hydrolase PF00702.26 CBZ37371.1 - 0.034 14.4 0.0 0.044 14.1 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NIF PF03031.18 CBZ37371.1 - 0.043 13.6 0.0 0.22 11.3 0.0 1.9 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase HAD PF12710.7 CBZ37371.1 - 0.18 12.2 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2384 PF09722.10 CBZ37372.1 - 0.012 15.6 0.3 0.052 13.6 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) Tup_N PF08581.10 CBZ37372.1 - 0.16 12.3 7.2 0.56 10.5 1.1 2.5 2 0 0 2 2 2 0 Tup N-terminal Spc7 PF08317.11 CBZ37372.1 - 0.49 9.2 2.8 0.73 8.6 0.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF29 PF01724.16 CBZ37375.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF29 DUF3903 PF13043.6 CBZ37375.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3903) DUF1279 PF06916.13 CBZ37376.1 - 0.29 11.7 1.2 0.5 10.9 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1279) FSA_C PF10479.9 CBZ37376.1 - 1.2 7.1 8.7 1.7 6.7 8.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF1279 PF06916.13 CBZ37377.1 - 0.0022 18.5 0.1 0.0038 17.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) CFAP91 PF14738.6 CBZ37378.1 - 1.4e-45 155.1 2.3 1.4e-45 155.1 2.3 2.1 2 1 0 2 2 2 1 Cilia- and flagella-associated protein 91 Baculo_IE-1 PF05290.11 CBZ37381.1 - 0.0011 18.9 1.9 0.0018 18.2 1.9 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.6 CBZ37381.1 - 0.11 12.4 13.2 0.17 11.8 13.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Bac_small_YrzI PF09501.10 CBZ37381.1 - 0.43 10.8 3.0 1.3 9.2 3.0 1.7 1 1 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) zf-RING_2 PF13639.6 CBZ37381.1 - 0.51 10.7 13.5 0.82 10.0 13.5 1.3 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 CBZ37381.1 - 9.2 6.1 12.7 24 4.8 12.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_hydro_85 PF03644.13 CBZ37382.1 - 8.6e-86 288.1 0.0 1.5e-85 287.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Peptidase_C97 PF05903.14 CBZ37382.1 - 2e-21 76.4 0.0 3.5e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUB PF09409.10 CBZ37382.1 - 8.6e-13 48.0 0.0 1.7e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 PUB domain DUF3421 PF11901.8 CBZ37382.1 - 1.4e-08 34.7 0.2 0.00038 20.4 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3421) Fungal_TACC PF12709.7 CBZ37383.1 - 0.19 12.2 5.5 0.33 11.4 0.4 2.6 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins APG6_N PF17675.1 CBZ37383.1 - 0.43 11.1 28.1 1.5 9.4 5.1 3.6 2 1 1 3 3 3 0 Apg6 coiled-coil region Tup_N PF08581.10 CBZ37383.1 - 0.77 10.1 9.1 0.16 12.3 2.4 2.7 2 0 0 2 2 2 0 Tup N-terminal FlxA PF14282.6 CBZ37383.1 - 1.3 9.1 11.9 0.088 12.8 3.6 2.5 2 1 0 2 2 2 0 FlxA-like protein zf-MYND PF01753.18 CBZ37384.1 - 1.2e-07 31.7 9.9 1.2e-07 31.7 9.9 2.0 2 0 0 2 2 2 1 MYND finger Pkinase PF00069.25 CBZ37385.1 - 6.7e-54 183.0 0.0 9.4e-49 166.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37385.1 - 4.9e-39 134.2 0.0 6.7e-37 127.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CBZ37385.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBZ37385.1 - 0.00047 19.6 0.0 0.0016 17.8 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ37385.1 - 0.0063 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBZ37385.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CBZ37385.1 - 0.12 12.3 0.3 19 5.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Epimerase PF01370.21 CBZ37386.1 - 4e-38 131.2 0.0 5e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CBZ37386.1 - 6.3e-33 114.6 0.0 6.2e-31 108.0 0.0 2.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CBZ37386.1 - 1.4e-14 53.9 0.0 1.7e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CBZ37386.1 - 3.3e-09 36.2 0.0 2.7e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CBZ37386.1 - 1.7e-07 30.7 0.0 6.4e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 CBZ37386.1 - 0.002 18.0 0.0 0.009 15.9 0.0 2.0 2 1 0 2 2 2 1 KR domain RmlD_sub_bind PF04321.17 CBZ37386.1 - 0.0035 16.5 0.0 0.015 14.4 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain CDC45 PF02724.14 CBZ37388.1 - 7.8e-85 285.5 0.0 9.2e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein UPF0561 PF10573.9 CBZ37388.1 - 0.2 11.8 7.3 0.57 10.3 7.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Spem1 PF15670.5 CBZ37388.1 - 0.72 9.4 5.4 1.8 8.1 5.4 1.6 1 0 0 1 1 1 0 Spermatid maturation protein 1 TGF_beta_GS PF08515.12 CBZ37388.1 - 0.84 9.2 4.3 1.9 8.0 4.3 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Nbs1_C PF08599.10 CBZ37388.1 - 1.3 9.2 4.7 1.9 8.7 0.7 2.8 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 Prp19 PF08606.11 CBZ37389.1 - 0.18 11.8 9.5 0.24 11.4 0.6 3.2 2 0 0 2 2 2 0 Prp19/Pso4-like Peptidase_C98 PF15499.6 CBZ37389.1 - 4.8 6.6 6.1 9.2 5.6 3.8 2.5 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase CoA_trans PF01144.23 CBZ37390.1 - 3.1e-96 321.0 1.3 2.4e-60 203.6 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CBZ37390.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain NCA2 PF08637.10 CBZ37391.1 - 3.2e-36 125.0 0.1 1.6e-26 93.1 0.0 2.2 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 GRASP55_65 PF04495.14 CBZ37393.1 - 8.8e-47 158.9 0.0 7.6e-41 139.7 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 CBZ37393.1 - 0.053 13.9 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 PDZ domain IBV_3A PF03617.13 CBZ37393.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 IBV 3A protein HSP90 PF00183.18 CBZ37394.1 - 8.3e-95 318.6 2.1 6.5e-93 312.4 0.3 2.0 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 CBZ37394.1 - 1e-10 41.6 0.0 2.4e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBZ37394.1 - 2.6e-07 31.1 0.0 4.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DPRP PF04244.13 CBZ37394.1 - 0.0084 16.0 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 Deoxyribodipyrimidine photo-lyase-related protein Ph1570 PF09638.10 CBZ37394.1 - 0.086 12.7 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Ph1570 protein MMR_HSR1 PF01926.23 CBZ37395.1 - 6.8e-18 64.8 0.1 4.8e-13 49.2 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ37395.1 - 2.6e-11 43.3 1.2 3.6e-09 36.4 0.2 2.5 3 0 0 3 3 3 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ37395.1 - 8.1e-06 25.8 0.3 0.00019 21.4 0.3 2.5 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CBZ37395.1 - 0.00013 21.6 0.1 0.0012 18.4 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CBZ37395.1 - 0.0014 18.7 0.3 0.037 14.1 0.1 2.6 2 1 1 3 3 3 1 Dynamin family AAA_18 PF13238.6 CBZ37395.1 - 0.014 16.0 0.0 0.046 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CBZ37395.1 - 0.032 13.2 0.5 0.14 11.2 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CBZ37395.1 - 0.11 12.1 0.6 0.47 10.0 0.2 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MSL1_dimer PF16801.5 CBZ37395.1 - 8.3 6.3 9.1 0.11 12.3 1.1 2.1 2 0 0 2 2 2 0 Dimerisation domain of Male-specific-Lethal 1 Diphthamide_syn PF01866.17 CBZ37396.1 - 1.2e-43 149.7 0.1 1.5e-23 83.8 0.0 3.0 3 0 0 3 3 3 2 Putative diphthamide synthesis protein DUF3708 PF12501.8 CBZ37396.1 - 0.15 11.8 0.1 0.15 11.8 0.1 3.1 3 0 0 3 3 3 0 Phosphate ATP-binding cassette transporter zf-MYND PF01753.18 CBZ37397.1 - 1.3e-08 34.8 45.5 3.3e-05 23.9 17.1 3.0 3 0 0 3 3 3 2 MYND finger zf-C3HC PF07967.13 CBZ37400.1 - 0.017 15.1 2.7 2.2 8.3 0.1 3.0 3 0 0 3 3 3 0 C3HC zinc finger-like DUF4569 PF15133.6 CBZ37400.1 - 7.4 6.2 9.8 17 5.0 9.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Tox-WTIP PF15654.6 CBZ37402.1 - 0.0029 18.0 0.1 0.02 15.3 0.0 2.3 2 0 0 2 2 2 1 Toxin with a conserved tryptophan and TIP tripeptide motif RE_HindIII PF09518.10 CBZ37402.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 HindIII restriction endonuclease KorB PF08535.10 CBZ37403.1 - 0.0019 18.2 0.0 0.0082 16.2 0.0 2.1 2 1 0 2 2 2 1 KorB domain Rad51 PF08423.11 CBZ37404.1 - 1.3e-32 113.0 0.0 9.6e-22 77.5 0.2 4.0 3 1 1 4 4 4 3 Rad51 AAA_25 PF13481.6 CBZ37404.1 - 2.3e-09 37.1 0.0 6.6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CBZ37404.1 - 0.0001 21.7 0.2 0.00025 20.5 0.2 1.6 1 0 0 1 1 1 1 KaiC RecA PF00154.21 CBZ37404.1 - 0.0002 20.9 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 CBZ37404.1 - 0.083 13.3 0.0 0.26 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CBZ37404.1 - 0.13 12.2 0.0 0.36 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 CBZ37404.1 - 0.15 12.5 0.0 0.44 11.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Radial_spoke PF04712.12 CBZ37405.1 - 5.3e-08 32.2 0.0 6e-07 28.8 0.0 2.2 3 0 0 3 3 3 1 Radial spokehead-like protein WcbI PF18588.1 CBZ37406.1 - 0.052 13.2 1.0 0.12 11.9 1.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI UDPGP PF01704.18 CBZ37407.1 - 2e-24 86.0 0.0 1.5e-23 83.2 0.0 1.9 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CBZ37407.1 - 0.014 15.8 0.6 0.014 15.8 0.6 2.8 3 1 1 4 4 4 0 MobA-like NTP transferase domain NUC173 PF08161.12 CBZ37408.1 - 6.7e-13 48.8 5.9 3.3e-12 46.5 0.9 3.5 2 1 0 2 2 2 1 NUC173 domain VCPO_N PF17897.1 CBZ37408.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Vanadium chloroperoxidase N-terminal domain Peptidase_M32 PF02074.15 CBZ37409.1 - 2.3e-160 534.6 0.0 2.6e-160 534.4 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase Iso_dh PF00180.20 CBZ37410.1 - 1.5e-106 356.5 0.0 1.9e-106 356.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.12 CBZ37410.1 - 0.012 15.0 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA Kinesin PF00225.23 CBZ37411.1 - 4.9e-102 341.3 0.0 8.1e-102 340.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ37411.1 - 1.1e-20 74.1 0.0 3.8e-20 72.3 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 CBZ37411.1 - 1.2e-05 25.8 0.0 0.02 15.3 0.0 3.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ37411.1 - 2.1e-05 24.8 1.0 0.02 15.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CBZ37411.1 - 0.0011 18.7 0.2 0.19 11.5 0.0 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CBZ37411.1 - 0.0016 17.8 0.0 0.28 10.5 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 CBZ37411.1 - 0.0026 17.7 0.0 0.025 14.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CBZ37411.1 - 0.013 16.0 0.0 0.08 13.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 CBZ37411.1 - 0.02 15.1 0.0 0.02 15.1 0.0 2.7 2 0 0 2 2 1 0 AAA domain CPT PF07931.12 CBZ37411.1 - 0.03 14.2 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SmpA_OmlA PF04355.13 CBZ37411.1 - 0.044 13.6 0.1 0.24 11.2 0.1 2.2 2 1 1 3 3 3 0 SmpA / OmlA family Ras PF00071.22 CBZ37411.1 - 0.047 13.3 0.0 7.3 6.2 0.0 2.9 3 0 0 3 3 3 0 Ras family RNA_helicase PF00910.22 CBZ37411.1 - 0.064 13.6 0.4 6.2 7.3 0.0 3.2 3 0 0 3 3 3 0 RNA helicase IstB_IS21 PF01695.17 CBZ37411.1 - 0.068 12.9 0.0 5.5 6.7 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 CBZ37411.1 - 0.094 12.4 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CBZ37411.1 - 0.095 12.8 0.1 2.9 8.0 0.0 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase Roc PF08477.13 CBZ37411.1 - 0.1 12.8 0.0 1 9.6 0.0 2.7 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 CBZ37411.1 - 0.11 12.0 0.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Mito_fiss_reg PF05308.11 CBZ37411.1 - 0.17 11.9 0.0 0.17 11.9 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator AAA_33 PF13671.6 CBZ37411.1 - 0.39 10.9 0.0 0.39 10.9 0.0 2.5 3 0 0 3 3 2 0 AAA domain Peptidase_M17 PF00883.21 CBZ37412.1 - 9.6e-93 310.9 0.1 9.6e-93 310.9 0.1 1.8 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 CBZ37412.1 - 2.1e-28 99.0 4.2 2.1e-28 99.0 4.2 1.8 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 UPF0767 PF15990.5 CBZ37413.1 - 0.089 12.9 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 UPF0767 family 3HCDH_N PF02737.18 CBZ37416.1 - 3.5e-42 144.3 0.0 6e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CBZ37416.1 - 5.2e-20 71.9 0.2 8.6e-09 35.9 0.1 3.5 3 0 0 3 3 3 3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DAO PF01266.24 CBZ37416.1 - 0.0001 22.1 0.2 0.0002 21.1 0.2 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 CBZ37416.1 - 0.00044 20.5 0.0 0.00085 19.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 CBZ37416.1 - 0.00093 18.5 2.6 0.025 13.8 0.2 1.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CBZ37416.1 - 0.0037 16.9 0.0 0.0071 16.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 CBZ37416.1 - 0.0044 17.0 0.0 0.0082 16.1 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 CBZ37416.1 - 0.0048 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CBZ37416.1 - 0.015 15.9 0.1 0.039 14.5 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 CBZ37416.1 - 0.015 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 CBZ37416.1 - 0.015 15.6 0.1 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 CBZ37416.1 - 0.042 14.0 0.1 0.15 12.2 0.1 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.20 CBZ37416.1 - 0.069 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus IlvN PF07991.12 CBZ37416.1 - 0.082 12.5 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Ldh_1_N PF00056.23 CBZ37416.1 - 0.15 12.2 0.6 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.21 CBZ37416.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 ThiF family Peptidase_M16_C PF05193.21 CBZ37417.1 - 2.9e-19 69.8 0.0 5.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CBZ37417.1 - 0.00051 20.1 0.0 0.0015 18.5 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) SRPRB PF09439.10 CBZ37418.1 - 1.7e-19 70.0 0.0 2.8e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBZ37418.1 - 8.7e-05 22.6 0.0 0.00018 21.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ37418.1 - 0.00019 21.1 0.1 0.001 18.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 CBZ37418.1 - 0.019 15.5 0.0 0.1 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 CBZ37418.1 - 0.022 13.7 0.1 0.91 8.4 0.0 2.4 2 0 0 2 2 2 0 YcjX-like family, DUF463 RsgA_GTPase PF03193.16 CBZ37418.1 - 0.028 14.3 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CBZ37418.1 - 0.041 14.2 0.7 0.13 12.5 0.1 2.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ37418.1 - 0.078 13.3 0.2 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ37418.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CBZ37418.1 - 0.27 10.8 0.8 0.38 10.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CBZ37418.1 - 0.29 11.5 3.4 0.74 10.2 0.3 2.8 2 2 0 2 2 2 0 AAA ATPase domain LIM PF00412.22 CBZ37420.1 - 1.1e-05 25.6 0.3 1.9e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 LIM domain ThiF PF00899.21 CBZ37421.1 - 6.9e-07 28.9 0.0 2.7e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 ThiF family zf-C2H2_10 PF16588.5 CBZ37422.1 - 4.3 7.1 10.3 0.31 10.8 0.8 2.9 2 0 0 2 2 2 0 C2H2 zinc-finger Filament PF00038.21 CBZ37423.1 - 0.0013 18.3 6.1 0.0013 18.3 6.1 6.6 2 1 3 5 5 5 2 Intermediate filament protein Lzipper-MIP1 PF14389.6 CBZ37423.1 - 0.15 12.4 0.0 0.15 12.4 0.0 9.9 5 3 4 10 10 10 0 Leucine-zipper of ternary complex factor MIP1 Coat_F PF07875.12 CBZ37423.1 - 0.71 10.1 3.5 28 5.1 0.2 3.2 2 0 0 2 2 2 0 Coat F domain DnaJ PF00226.31 CBZ37425.1 - 1.4e-09 38.0 0.1 3.8e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Dor1 PF04124.12 CBZ37425.1 - 0.021 13.6 0.0 0.025 13.2 0.0 1.3 1 0 0 1 1 1 0 Dor1-like family Mis12 PF05859.12 CBZ37425.1 - 0.065 13.3 1.2 0.26 11.3 0.3 2.3 2 1 1 3 3 3 0 Mis12 protein FlaG PF03646.15 CBZ37425.1 - 0.084 13.0 0.6 0.084 13.0 0.6 2.1 2 0 0 2 2 2 0 FlaG protein CENP-X PF09415.10 CBZ37425.1 - 0.11 12.8 0.9 0.3 11.4 0.9 1.9 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Latarcin PF10279.9 CBZ37425.1 - 0.5 10.8 2.8 3.7 8.0 0.0 2.9 2 1 0 2 2 2 0 Latarcin precursor MCM PF00493.23 CBZ37426.1 - 6.6e-84 280.5 0.0 1.3e-83 279.5 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CBZ37426.1 - 1.5e-26 92.7 0.0 2.6e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CBZ37426.1 - 7.1e-20 71.2 0.0 1.5e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CBZ37426.1 - 1.1e-08 35.6 0.0 4e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CBZ37426.1 - 2e-08 33.9 0.1 6.5e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CBZ37426.1 - 0.00036 20.3 0.0 0.002 17.9 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 CBZ37426.1 - 0.0016 18.3 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ37426.1 - 0.032 14.2 0.0 0.17 11.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CBZ37426.1 - 0.074 13.5 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Complex1_LYR PF05347.15 CBZ37427.1 - 5.7e-05 23.1 1.0 0.0001 22.3 1.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Misat_Tub_SegII PF10644.9 CBZ37427.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain ketoacyl-synt PF00109.26 CBZ37428.1 - 2.7e-37 128.7 0.6 9.6e-37 126.9 0.6 1.9 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CBZ37428.1 - 4.3e-27 94.5 0.8 4.3e-27 94.5 0.8 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain FAM153 PF15722.5 CBZ37428.1 - 0.2 12.0 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 FAM153 family A2M_BRD PF07703.14 CBZ37429.1 - 0.16 12.3 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin bait region domain GTP_EFTU PF00009.27 CBZ37430.1 - 3.8e-35 121.2 0.0 1.1e-34 119.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CBZ37430.1 - 1.2e-15 57.5 0.0 2.8e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CBZ37430.1 - 6.6e-10 39.3 1.8 3.9e-07 30.4 0.0 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CBZ37430.1 - 1.5e-08 34.4 2.0 1.9e-08 34.1 0.7 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 CBZ37430.1 - 8.3e-08 32.3 0.0 5.8e-07 29.6 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 CBZ37430.1 - 7.9e-05 22.9 0.0 0.00018 21.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CBZ37430.1 - 0.0062 16.5 0.6 0.82 9.6 0.1 3.1 1 1 1 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 CBZ37430.1 - 0.012 15.4 0.0 0.042 13.6 0.0 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CBZ37430.1 - 0.02 15.3 0.0 0.02 15.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Ras PF00071.22 CBZ37430.1 - 0.034 13.8 0.0 0.14 11.7 0.0 2.0 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.23 CBZ37430.1 - 0.19 11.7 15.5 0.094 12.8 6.2 4.0 2 1 0 2 2 2 0 Dynamin family DUF4520 PF15016.6 CBZ37431.1 - 8e-21 73.9 0.1 5.7e-19 68.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) DUF3247 PF11607.8 CBZ37431.1 - 0.07 13.4 0.1 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3247) Carboxyl_trans PF01039.22 CBZ37431.1 - 0.23 10.0 0.1 0.4 9.2 0.1 1.3 1 0 0 1 1 1 0 Carboxyl transferase domain Corona_NS3b PF03053.14 CBZ37431.1 - 0.28 10.9 0.0 0.45 10.2 0.0 1.2 1 0 0 1 1 1 0 ORF3b coronavirus protein UQ_con PF00179.26 CBZ37433.1 - 7.1e-35 119.7 0.0 9.7e-35 119.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FAM199X PF15814.5 CBZ37433.1 - 0.00072 18.7 0.5 0.00082 18.5 0.5 1.1 1 0 0 1 1 1 1 Protein family FAM199X BRE PF06113.12 CBZ37433.1 - 0.054 12.3 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Prok-E2_B PF14461.6 CBZ37433.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.7 2 1 0 2 2 2 0 Prokaryotic E2 family B Beach PF02138.18 CBZ37434.1 - 5.1e-95 318.0 0.0 1e-94 317.0 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.6 CBZ37434.1 - 3.6e-07 30.4 0.5 1.2e-06 28.8 0.5 2.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily GTP_EFTU PF00009.27 CBZ37435.1 - 2e-18 66.6 0.0 1.3e-17 64.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ37435.1 - 2e-05 24.9 0.4 6.7e-05 23.2 0.4 1.9 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CBZ37435.1 - 2.5e-05 24.6 0.8 6.1e-05 23.3 0.8 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ37435.1 - 0.013 15.5 0.0 0.078 13.1 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBZ37435.1 - 0.027 14.2 0.2 2 8.2 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TFIIS_C PF01096.18 CBZ37437.1 - 1.7e-14 53.4 8.8 3.5e-14 52.4 8.8 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) PWWP PF00855.17 CBZ37437.1 - 4.2e-06 27.1 0.2 2.2e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 PWWP domain Med26 PF08711.11 CBZ37437.1 - 0.089 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain UBD PF16455.5 CBZ37437.1 - 0.09 13.0 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-binding domain Sporozoite_P67 PF05642.11 CBZ37437.1 - 3.1 5.8 4.4 4 5.4 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PWWP PF00855.17 CBZ37438.1 - 6.7e-11 42.5 1.6 7e-11 42.4 0.0 1.9 2 0 0 2 2 1 1 PWWP domain Med26 PF08711.11 CBZ37438.1 - 8.9e-07 28.8 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Zn_ribbon_SprT PF17283.2 CBZ37438.1 - 6.5e-05 22.8 1.3 0.00018 21.3 1.3 1.7 1 0 0 1 1 1 1 SprT-like zinc ribbon domain Lar_restr_allev PF14354.6 CBZ37438.1 - 0.0001 22.6 0.5 0.0003 21.1 0.5 1.9 1 0 0 1 1 1 1 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 CBZ37438.1 - 0.022 14.7 1.2 0.022 14.7 1.2 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TFIIS_C PF01096.18 CBZ37438.1 - 0.065 13.1 1.9 0.2 11.5 1.9 1.9 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) zinc_ribbon_4 PF13717.6 CBZ37438.1 - 0.12 12.3 2.3 0.87 9.6 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CBZ37438.1 - 0.44 10.0 2.0 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain SRP-alpha_N PF04086.13 CBZ37438.1 - 1.1 9.2 15.3 1.6 8.6 15.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Zn-ribbon_8 PF09723.10 CBZ37438.1 - 1.6 8.9 3.5 19 5.4 0.3 2.7 1 1 1 2 2 2 0 Zinc ribbon domain PBP1_TM PF14812.6 CBZ37438.1 - 7.4 7.0 21.3 10 6.6 14.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CHAP PF05257.16 CBZ37439.1 - 2.9e-17 63.0 0.1 1.1e-16 61.1 0.0 1.9 2 0 0 2 2 2 1 CHAP domain OppC_N PF12911.7 CBZ37440.1 - 0.26 11.3 0.8 0.93 9.5 0.3 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Macoilin PF09726.9 CBZ37440.1 - 0.43 9.1 1.4 0.59 8.6 1.4 1.2 1 0 0 1 1 1 0 Macoilin family Y_phosphatase3 PF13350.6 CBZ37441.1 - 8.2e-49 166.7 0.2 9.2e-49 166.5 0.2 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CBZ37441.1 - 0.019 14.6 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF5010 PF16402.5 CBZ37441.1 - 0.17 10.7 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) CHAP PF05257.16 CBZ37442.1 - 3e-16 59.8 0.0 6.3e-16 58.7 0.0 1.6 1 1 0 1 1 1 1 CHAP domain TetR_C_16 PF17920.1 CBZ37442.1 - 0.085 13.1 0.2 0.23 11.7 0.2 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CHAP PF05257.16 CBZ37443.1 - 5.3e-06 26.9 1.1 8.1e-05 23.1 0.0 2.9 2 1 0 2 2 2 1 CHAP domain Kinesin PF00225.23 CBZ37446.1 - 0.00093 18.2 0.0 0.068 12.1 0.0 2.9 2 1 0 2 2 2 2 Kinesin motor domain DUF2499 PF10693.9 CBZ37447.1 - 0.041 14.2 0.5 1.6 9.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) HBS1_N PF08938.10 CBZ37448.1 - 0.039 14.3 0.1 0.17 12.2 0.1 2.1 1 0 0 1 1 1 0 HBS1 N-terminus Kinesin PF00225.23 CBZ37449.1 - 4.4e-08 32.4 0.0 0.14 11.0 0.0 5.1 5 1 0 5 5 5 2 Kinesin motor domain RRM_occluded PF16842.5 CBZ37449.1 - 0.057 13.3 0.3 0.91 9.4 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif DUF4835 PF16119.5 CBZ37454.1 - 0.099 11.7 0.3 0.17 11.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) ABC_tran PF00005.27 CBZ37462.1 - 2.7e-10 40.9 0.0 0.0003 21.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SbcCD_C PF13558.6 CBZ37462.1 - 0.0005 20.2 0.9 0.0046 17.2 0.3 2.7 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 CBZ37462.1 - 0.042 14.1 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Tyr-DNA_phospho PF06087.12 CBZ37463.1 - 8.5e-68 229.2 0.0 1.2e-67 228.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase SH2_2 PF14633.6 CBZ37466.1 - 2.5e-20 72.8 0.1 4.7e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 SH2 domain YqgF PF14639.6 CBZ37466.1 - 3.4e-11 43.1 0.0 1.3e-10 41.2 0.0 2.0 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 Tex_YqgF PF16921.5 CBZ37466.1 - 0.00067 20.1 0.0 0.0015 19.0 0.0 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain SH2 PF00017.24 CBZ37466.1 - 0.066 13.3 0.4 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 SH2 domain HHH_7 PF14635.6 CBZ37466.1 - 0.093 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif TetR_C_15 PF17918.1 CBZ37466.1 - 0.1 13.4 6.1 0.083 13.7 1.4 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Trypsin_2 PF13365.6 CBZ37469.1 - 6.8e-07 30.3 0.1 1.6e-06 29.1 0.1 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CBZ37469.1 - 0.013 15.3 0.3 0.022 14.6 0.3 1.6 1 1 0 1 1 1 0 Trypsin Ribosomal_S13_N PF08069.12 CBZ37471.1 - 8.4e-25 86.6 1.8 1.6e-24 85.7 1.8 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CBZ37471.1 - 4.1e-13 49.3 1.0 6.8e-13 48.6 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 DUF3958 PF13125.6 CBZ37472.1 - 0.09 13.0 0.3 0.09 13.0 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3958) DUF1664 PF07889.12 CBZ37473.1 - 0.057 13.5 4.8 31 4.6 0.2 4.0 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) BRX_N PF13713.6 CBZ37473.1 - 0.08 12.7 0.0 0.31 10.8 0.0 2.0 2 0 0 2 2 2 0 Transcription factor BRX N-terminal domain AAA_13 PF13166.6 CBZ37473.1 - 0.12 11.0 0.8 4.4 5.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain FliT PF05400.13 CBZ37473.1 - 0.44 11.4 8.6 1.4 9.8 0.6 4.1 3 2 0 3 3 3 0 Flagellar protein FliT PhaP_Bmeg PF09602.10 CBZ37473.1 - 0.55 10.1 3.0 1.7 8.6 0.1 2.6 3 0 0 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) kleA_kleC PF17383.2 CBZ37473.1 - 1 9.7 4.7 0.93 9.9 0.3 2.8 2 2 0 2 2 2 0 Uncharacterized KorC regulated protein A Rootletin PF15035.6 CBZ37473.1 - 1.3 9.0 7.4 0.89 9.5 1.0 2.5 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion TMF_TATA_bd PF12325.8 CBZ37473.1 - 1.3 9.3 4.8 1.9 8.7 0.4 2.9 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 CBZ37473.1 - 2.4 8.2 11.3 23 5.0 0.1 4.1 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cep57_CLD_2 PF14197.6 CBZ37473.1 - 2.8 8.1 8.2 1.5 9.0 0.9 3.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Spectrin PF00435.21 CBZ37473.1 - 6.4 7.3 6.4 28 5.3 0.4 3.1 3 1 1 4 4 4 0 Spectrin repeat PepSY_TM PF03929.16 CBZ37474.1 - 0.026 14.2 0.3 0.026 14.2 0.3 4.0 2 1 1 3 3 3 0 PepSY-associated TM region EphA2_TM PF14575.6 CBZ37474.1 - 0.26 12.2 17.6 4.7 8.2 0.1 5.6 2 1 3 5 5 5 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 CBZ37474.1 - 0.41 10.9 0.0 0.41 10.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TAF4 PF05236.14 CBZ37474.1 - 1.6 8.4 3.5 2.5 7.7 3.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family SRP9-21 PF05486.12 CBZ37474.1 - 6.5 7.2 6.3 26 5.3 0.2 3.7 1 1 1 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) LSM PF01423.22 CBZ37475.1 - 6.8e-14 51.3 0.1 9.5e-14 50.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain Zip PF02535.22 CBZ37476.1 - 8.8e-37 127.1 18.6 1.3e-24 87.0 10.9 2.0 1 1 1 2 2 2 2 ZIP Zinc transporter Coatomer_WDAD PF04053.14 CBZ37477.1 - 2.1e-138 462.1 0.0 3.4e-138 461.4 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CBZ37477.1 - 9.5e-28 95.9 1.2 3.1e-07 31.0 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37477.1 - 5e-08 33.1 0.0 2.2 8.6 0.0 5.8 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain TPR_8 PF13181.6 CBZ37477.1 - 0.015 15.5 0.4 0.13 12.6 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat eIF2A PF08662.11 CBZ37477.1 - 0.029 14.3 0.0 6.5 6.6 0.0 3.5 2 2 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 CBZ37477.1 - 0.036 14.1 0.0 18 5.4 0.0 4.0 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region Clathrin PF00637.20 CBZ37477.1 - 0.1 12.5 0.3 4.3 7.2 0.0 2.7 1 1 2 3 3 3 0 Region in Clathrin and VPS EF-hand_7 PF13499.6 CBZ37478.1 - 4.1e-06 27.1 0.0 0.00011 22.6 0.0 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CBZ37478.1 - 0.00014 21.5 0.0 0.0058 16.5 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CBZ37478.1 - 0.00018 20.8 0.0 0.00043 19.7 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CBZ37478.1 - 0.0029 17.1 0.0 0.04 13.5 0.0 2.6 2 0 0 2 2 2 1 EF hand Ribosomal_L44 PF00935.19 CBZ37479.1 - 1.2e-31 109.0 9.1 1.7e-31 108.5 9.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 AAA-ATPase_like PF09820.9 CBZ37481.1 - 1.8 7.9 3.4 1.9 7.8 1.6 1.9 1 1 1 2 2 2 0 Predicted AAA-ATPase ABC_tran PF00005.27 CBZ37482.1 - 1.7e-18 67.5 0.0 2.7e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 CBZ37482.1 - 0.0085 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CBZ37482.1 - 0.0089 16.4 0.0 0.031 14.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 CBZ37482.1 - 0.065 12.7 0.0 1.1 8.6 0.0 1.9 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain Cys_Met_Meta_PP PF01053.20 CBZ37482.1 - 0.1 11.1 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme MMR_HSR1 PF01926.23 CBZ37482.1 - 0.2 11.7 0.1 0.55 10.3 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase FA_desaturase PF00487.24 CBZ37483.1 - 1.2e-23 84.3 31.8 1.2e-23 84.3 31.8 1.7 1 1 1 2 2 2 2 Fatty acid desaturase UPF0114 PF03350.16 CBZ37483.1 - 0.075 13.2 0.0 0.59 10.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 adh_short PF00106.25 CBZ37484.1 - 2.8e-35 121.6 0.0 3.5e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ37484.1 - 1e-21 77.6 0.0 1.4e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ37484.1 - 0.0029 17.5 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Exog_C PF18026.1 CBZ37484.1 - 0.011 15.8 0.1 0.039 14.0 0.0 2.0 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain Sacchrp_dh_NADP PF03435.18 CBZ37484.1 - 0.011 15.9 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LRR_4 PF12799.7 CBZ37485.1 - 1.2e-06 28.7 9.9 0.13 12.7 0.7 6.0 2 1 8 10 10 10 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ37485.1 - 0.024 14.4 10.7 0.16 11.7 0.1 5.3 2 1 6 8 8 8 0 Leucine rich repeat LRR_5 PF13306.6 CBZ37485.1 - 0.075 13.0 0.0 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 CBZ37485.1 - 0.091 12.9 13.7 26 5.2 0.0 7.0 8 0 0 8 8 8 0 Leucine Rich repeat Pkinase PF00069.25 CBZ37486.1 - 1.7e-40 139.1 0.0 2.2e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37486.1 - 8.4e-24 84.2 0.0 9.9e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ37486.1 - 3.6e-06 26.5 0.0 1e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like DnaJ PF00226.31 CBZ37487.1 - 7.4e-12 45.2 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Wzy_C_2 PF11846.8 CBZ37487.1 - 2.6 7.9 9.0 1.1 9.2 0.6 2.8 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal CLPTM1 PF05602.12 CBZ37488.1 - 8.8e-99 331.4 0.0 1.1e-98 331.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) peroxidase PF00141.23 CBZ37490.1 - 4.4e-46 157.4 0.0 7.2e-46 156.7 0.0 1.3 1 1 0 1 1 1 1 Peroxidase G6PD_C PF02781.16 CBZ37491.1 - 2.6e-108 361.7 0.0 3.2e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CBZ37491.1 - 1.9e-57 194.7 0.0 3.4e-57 193.9 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain FliT PF05400.13 CBZ37493.1 - 0.071 13.9 0.1 0.68 10.8 0.0 2.6 2 0 0 2 2 2 0 Flagellar protein FliT NUDIX PF00293.28 CBZ37494.1 - 0.027 14.5 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain Herpes_UL52 PF03121.15 CBZ37494.1 - 5.1 7.1 6.8 9.9 6.2 6.8 1.4 1 0 0 1 1 1 0 Herpesviridae UL52/UL70 DNA primase ADK PF00406.22 CBZ37495.1 - 2.3e-51 173.9 0.0 2.7e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ37495.1 - 7.2e-23 81.5 0.0 1.3e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CBZ37495.1 - 3.1e-16 59.1 0.1 6.4e-16 58.0 0.1 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CBZ37495.1 - 0.0057 17.2 0.1 0.016 15.8 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ37495.1 - 0.025 14.7 0.0 0.065 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CBZ37495.1 - 0.074 13.3 0.0 0.31 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Hydin_ADK PF17213.3 CBZ37495.1 - 0.14 12.4 0.0 0.83 9.9 0.0 2.0 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain ADK PF00406.22 CBZ37496.1 - 1.5e-28 99.8 0.0 1.8e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 CBZ37496.1 - 3.8e-13 49.2 0.0 7.4e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 CBZ37496.1 - 6.1e-13 49.4 0.0 1.2e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 CBZ37496.1 - 5.6e-05 23.5 0.2 0.015 15.6 0.0 2.4 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 CBZ37496.1 - 0.0011 19.5 0.0 0.0029 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CBZ37496.1 - 0.0091 16.2 0.1 0.025 14.7 0.0 1.7 2 1 0 2 2 2 1 AAA domain MscS_porin PF12795.7 CBZ37496.1 - 0.023 14.2 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain AAA_28 PF13521.6 CBZ37496.1 - 0.035 14.3 0.0 0.066 13.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CBZ37496.1 - 0.072 12.8 0.1 0.26 11.0 0.0 1.9 1 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 CBZ37496.1 - 0.08 12.7 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase Ldh_1_C PF02866.18 CBZ37497.1 - 3.9e-15 56.2 0.0 1.5e-14 54.2 0.0 1.8 1 1 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CBZ37497.1 - 3.1e-12 46.8 0.0 5.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CBZ37497.1 - 0.032 13.6 0.2 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.23 CBZ37498.1 - 2.2e-45 154.2 0.2 2.9e-45 153.8 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBZ37498.1 - 2.5e-45 154.4 0.0 4.1e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CBZ37498.1 - 0.00022 20.3 0.0 0.00034 19.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CBZ37498.1 - 0.001 19.5 0.1 0.0026 18.2 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CBZ37498.1 - 0.0035 17.5 0.0 0.0079 16.3 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_C PF02866.18 CBZ37499.1 - 4.3e-37 127.6 0.0 7.6e-37 126.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CBZ37499.1 - 1.7e-36 125.4 0.0 2.3e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CBZ37499.1 - 0.00013 21.1 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CBZ37499.1 - 0.00089 19.7 0.0 0.0023 18.4 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CBZ37499.1 - 0.048 13.0 0.0 0.31 10.4 0.0 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.23 CBZ37500.1 - 1.2e-41 142.1 0.0 1.6e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CBZ37500.1 - 8e-40 136.5 0.0 1.2e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CBZ37500.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3756 PF12581.8 CBZ37500.1 - 0.31 11.0 1.5 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) Nop25 PF09805.9 CBZ37501.1 - 5.1e-12 46.4 2.4 5.1e-12 46.4 2.4 2.5 3 0 0 3 3 3 1 Nucleolar protein 12 (25kDa) FmdE PF02663.14 CBZ37501.1 - 0.0031 17.5 0.4 1.9 8.5 0.3 2.3 2 0 0 2 2 2 2 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Methyltransf_25 PF13649.6 CBZ37503.1 - 0.018 15.7 0.1 0.055 14.2 0.1 1.9 1 0 0 1 1 1 0 Methyltransferase domain NICE-1 PF15845.5 CBZ37503.1 - 5 8.0 12.6 0.34 11.7 5.4 2.9 3 0 0 3 3 3 0 Cysteine-rich C-terminal 1 family DUF1935 PF09149.10 CBZ37504.1 - 3e-120 393.7 4.2 7.1e-31 106.7 0.1 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) OCRE PF17780.1 CBZ37504.1 - 0.35 10.9 4.8 9.8 6.3 0.0 3.8 4 0 0 4 4 4 0 OCRE domain DUF1935 PF09149.10 CBZ37505.1 - 1.5e-115 378.6 0.0 6.8e-29 100.3 0.0 4.1 4 0 0 4 4 4 4 Domain of unknown function (DUF1935) CS PF04969.16 CBZ37506.1 - 4.3e-07 30.8 0.0 6.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 CS domain PIH1_CS PF18201.1 CBZ37506.1 - 0.094 13.1 0.0 0.19 12.2 0.0 1.5 1 1 0 1 1 1 0 PIH1 CS-like domain EMP24_GP25L PF01105.24 CBZ37507.1 - 2.3e-13 50.5 0.2 5.6e-13 49.2 0.2 1.7 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MCU PF04678.13 CBZ37507.1 - 0.071 13.2 0.3 0.12 12.5 0.3 1.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter IFT81_CH PF18383.1 CBZ37508.1 - 5.9e-31 107.3 0.1 2.8e-30 105.1 0.0 2.2 2 0 0 2 2 2 1 Intraflagellar transport 81 calponin homology domain Spc7 PF08317.11 CBZ37508.1 - 0.0014 17.6 7.9 0.0014 17.6 7.9 4.4 1 1 2 4 4 4 3 Spc7 kinetochore protein Cep57_MT_bd PF06657.13 CBZ37508.1 - 0.061 13.8 0.1 0.061 13.8 0.1 5.9 5 2 3 8 8 8 0 Centrosome microtubule-binding domain of Cep57 DUF465 PF04325.13 CBZ37508.1 - 0.14 12.3 0.2 0.14 12.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Baculo_PEP_C PF04513.12 CBZ37508.1 - 0.19 11.8 21.3 0.99 9.4 4.0 5.4 3 1 4 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus ORF6C PF10552.9 CBZ37508.1 - 0.53 10.4 5.0 0.24 11.5 0.9 2.6 2 0 0 2 2 2 0 ORF6C domain IZUMO PF15005.6 CBZ37508.1 - 5.2 7.6 22.3 1.2 9.6 0.1 5.1 2 2 4 6 6 6 0 Izumo sperm-egg fusion, Ig domain-associated DUF4051 PF13260.6 CBZ37509.1 - 1.6 8.6 4.5 2.4 8.0 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4051) RIIa PF02197.17 CBZ37511.1 - 1.5e-06 27.8 0.5 2.6e-06 27.0 0.5 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Dpy-30 PF05186.13 CBZ37511.1 - 0.00013 21.5 0.1 0.00031 20.4 0.1 1.7 1 1 0 1 1 1 1 Dpy-30 motif Sigma70_r2 PF04542.14 CBZ37511.1 - 0.025 14.4 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-70 region 2 DUF760 PF05542.11 CBZ37511.1 - 0.045 14.1 0.3 9.6 6.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF760) Pyr_redox_2 PF07992.14 CBZ37512.1 - 1.1e-09 38.0 0.0 2.3e-07 30.4 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ37512.1 - 0.00074 19.7 0.1 0.0022 18.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CBZ37512.1 - 0.0024 17.2 0.1 0.004 16.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CBZ37512.1 - 0.0032 17.1 3.2 0.07 12.7 1.1 2.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CBZ37512.1 - 0.0096 14.8 0.4 0.016 14.0 0.4 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 CBZ37512.1 - 0.013 14.6 0.4 0.025 13.7 0.4 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 CBZ37512.1 - 0.03 14.6 0.2 0.09 13.0 0.2 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox_3 PF13738.6 CBZ37512.1 - 0.045 13.0 0.4 3.1 7.0 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ37512.1 - 0.089 11.5 1.2 0.69 8.5 0.6 2.2 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.21 CBZ37512.1 - 0.089 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.6 CBZ37512.1 - 0.11 12.5 2.4 0.33 10.9 0.2 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.18 CBZ37512.1 - 0.12 12.6 0.4 0.35 11.1 0.4 1.8 1 1 0 1 1 1 0 TrkA-N domain FAD_binding_2 PF00890.24 CBZ37512.1 - 0.16 11.0 1.3 0.21 10.6 0.5 1.7 2 0 0 2 2 2 0 FAD binding domain LapA_dom PF06305.11 CBZ37512.1 - 0.18 11.6 0.5 0.56 10.1 0.5 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Peptidase_C2 PF00648.21 CBZ37513.1 - 6.6e-07 28.6 0.0 1.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Mon1 PF03164.14 CBZ37514.1 - 1.3e-30 106.8 0.0 5.8e-11 42.1 0.0 3.0 3 0 0 3 3 3 3 Trafficking protein Mon1 WD40 PF00400.32 CBZ37515.1 - 2.1e-14 53.6 5.1 0.0047 17.7 0.0 7.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37515.1 - 0.027 14.8 0.0 4.2 7.7 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PseudoU_synth_1 PF01416.20 CBZ37516.1 - 1.1e-11 45.2 0.0 2e-08 34.6 0.0 3.3 3 1 0 3 3 3 2 tRNA pseudouridine synthase Synaphin PF05835.12 CBZ37516.1 - 1.8 8.8 9.2 1.4 9.2 0.1 3.0 3 0 0 3 3 3 0 Synaphin protein START PF01852.19 CBZ37517.1 - 0.0032 16.9 0.1 0.0053 16.2 0.1 1.3 1 0 0 1 1 1 1 START domain DS PF01916.17 CBZ37518.1 - 3.6e-51 174.1 0.2 1.9e-35 122.5 0.0 4.2 3 1 1 4 4 4 4 Deoxyhypusine synthase AAA PF00004.29 CBZ37519.1 - 5.9e-09 36.5 0.0 1.6e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ37519.1 - 1.3e-06 28.5 0.0 3.1e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ37519.1 - 6.3e-05 23.4 0.1 0.00027 21.4 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_6 PF12774.7 CBZ37519.1 - 0.0026 16.8 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 CBZ37519.1 - 0.0032 17.6 0.0 0.0078 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ37519.1 - 0.0042 17.6 0.0 0.0084 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ37519.1 - 0.0048 17.2 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBZ37519.1 - 0.0092 15.5 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 CBZ37519.1 - 0.0097 16.3 0.0 0.033 14.6 0.0 1.9 2 0 0 2 2 1 1 RNA helicase Viral_helicase1 PF01443.18 CBZ37519.1 - 0.022 14.5 0.0 0.056 13.2 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 CBZ37519.1 - 0.025 13.7 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 CBZ37519.1 - 0.028 14.8 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CBZ37519.1 - 0.031 14.3 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FAD-SLDH PF12318.8 CBZ37519.1 - 0.041 13.9 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase AAA_17 PF13207.6 CBZ37519.1 - 0.066 13.6 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ37519.1 - 0.067 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CBZ37519.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBZ37519.1 - 0.17 11.6 0.0 0.17 11.6 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_2 PF07724.14 CBZ37519.1 - 0.17 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CBZ37519.1 - 0.19 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain eIF-5_eIF-2B PF01873.17 CBZ37520.1 - 5.7e-33 113.3 0.0 1.1e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CBZ37520.1 - 0.00095 19.3 0.0 0.0039 17.3 0.0 2.0 1 1 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RNA_pol_Rpb1_5 PF04998.17 CBZ37521.1 - 1.7e-76 257.2 0.0 2.4e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CBZ37521.1 - 3.5e-67 225.8 0.0 6.2e-67 225.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CBZ37521.1 - 5.5e-54 183.6 0.0 8.1e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 CBZ37521.1 - 7.4e-32 110.5 0.0 1.7e-31 109.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CBZ37521.1 - 2.5e-31 107.8 0.0 6.1e-31 106.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Rpr2 PF04032.16 CBZ37521.1 - 2.2 8.7 6.4 0.71 10.2 1.8 2.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain COG6 PF06419.11 CBZ37522.1 - 1.5e-47 162.2 0.1 3.5e-44 151.1 0.0 3.1 3 0 0 3 3 3 3 Conserved oligomeric complex COG6 Occludin_ELL PF07303.13 CBZ37522.1 - 0.0018 18.9 2.4 0.0035 18.1 1.4 2.0 1 1 0 1 1 1 1 Occludin homology domain Filament PF00038.21 CBZ37522.1 - 0.038 13.6 0.3 0.038 13.6 0.3 2.0 1 1 1 2 2 2 0 Intermediate filament protein DUF4766 PF15973.5 CBZ37522.1 - 0.044 14.4 0.7 0.22 12.1 0.7 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4766) DASH_Dad3 PF08656.10 CBZ37522.1 - 0.15 12.2 0.1 7.6 6.7 0.0 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF4785 PF16024.5 CBZ37524.1 - 0.21 10.3 0.1 0.32 9.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4785) Ribosomal_S6 PF01250.17 CBZ37525.1 - 0.0028 17.9 0.1 0.0044 17.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 GAS PF13851.6 CBZ37526.1 - 8.8e-06 25.2 1.5 4.9e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Troponin PF00992.20 CBZ37526.1 - 0.04 14.2 0.9 0.04 14.2 0.9 2.0 2 0 0 2 2 2 0 Troponin DUF4140 PF13600.6 CBZ37526.1 - 0.053 13.9 5.7 4 7.9 0.1 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) EzrA PF06160.12 CBZ37526.1 - 0.073 11.2 3.2 0.083 11.1 0.4 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA HMMR_N PF15905.5 CBZ37526.1 - 0.3 10.5 5.7 2.3 7.6 1.3 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Med9 PF07544.13 CBZ37526.1 - 0.49 10.5 2.3 2.1 8.5 0.3 2.8 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 HrpB7 PF09486.10 CBZ37526.1 - 1.2 9.5 14.7 2.1 8.7 5.9 3.0 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) Uso1_p115_C PF04871.13 CBZ37526.1 - 1.8 9.0 8.5 1.4 9.3 3.3 2.5 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region MIEAP PF16026.5 CBZ37527.1 - 0.014 15.6 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 Mitochondria-eating protein Ribosomal_S25 PF03297.15 CBZ37529.1 - 1.5e-36 124.7 5.5 1.7e-36 124.4 5.5 1.1 1 0 0 1 1 1 1 S25 ribosomal protein DUF3516 PF12029.8 CBZ37529.1 - 0.15 11.1 1.6 0.18 10.8 1.6 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3516) WD40 PF00400.32 CBZ37532.1 - 1.3e-36 124.0 24.2 7.2e-07 29.8 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37532.1 - 2.3e-07 31.0 0.0 0.045 14.0 0.0 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CBZ37532.1 - 0.052 12.1 0.1 15 4.0 0.0 3.2 4 0 0 4 4 4 0 Cytochrome D1 heme domain Ion_trans PF00520.31 CBZ37533.1 - 8.6e-118 391.9 108.4 1.8e-38 132.2 19.7 4.2 4 0 0 4 4 4 4 Ion transport protein GPHH PF16905.5 CBZ37533.1 - 0.0027 17.4 0.0 0.0081 15.9 0.0 1.9 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated HEAT PF02985.22 CBZ37534.1 - 9.4e-13 47.2 6.5 0.7 10.3 0.0 8.9 8 1 1 9 9 9 5 HEAT repeat HEAT_2 PF13646.6 CBZ37534.1 - 1.2e-09 38.4 4.9 0.017 15.5 0.1 6.1 4 2 1 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 CBZ37534.1 - 4.6e-09 36.6 12.2 0.00011 22.6 0.1 6.5 5 3 2 7 7 7 3 HEAT-like repeat Arm PF00514.23 CBZ37534.1 - 7.8e-08 32.1 5.2 0.2 11.7 0.0 5.5 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 CBZ37534.1 - 9e-08 31.9 0.0 5.9e-07 29.3 0.0 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 CBZ37534.1 - 2.6e-05 23.0 0.9 0.059 11.9 0.1 3.1 3 0 0 3 3 3 2 Adaptin N terminal region DUF3385 PF11865.8 CBZ37534.1 - 0.00043 20.2 1.7 2.4 8.1 0.1 5.2 4 2 2 6 6 6 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 CBZ37534.1 - 0.0076 16.8 3.4 13 6.5 0.1 4.9 4 3 1 5 5 5 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CBZ37534.1 - 0.019 14.6 1.4 0.72 9.4 0.0 3.5 3 1 1 4 4 4 0 CLASP N terminal Spidroin_N PF16763.5 CBZ37534.1 - 0.02 14.9 1.2 13 5.8 0.8 3.3 2 0 0 2 2 2 0 Major ampullate spidroin 1, spider silk protein 1, N-term U3snoRNP10 PF12397.8 CBZ37534.1 - 0.031 14.6 2.7 34 4.8 0.0 5.1 4 1 1 5 5 5 0 U3 small nucleolar RNA-associated protein 10 Telomere_reg-2 PF10193.9 CBZ37534.1 - 0.24 11.9 3.7 9.2 6.8 0.1 4.1 3 1 0 3 3 3 0 Telomere length regulation protein NopRA1 PF16201.5 CBZ37534.1 - 0.27 10.8 1.6 3 7.4 0.2 3.5 4 1 0 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Macoilin PF09726.9 CBZ37535.1 - 5.6 5.4 18.5 6.9 5.1 18.5 1.1 1 0 0 1 1 1 0 Macoilin family O-FucT PF10250.9 CBZ37536.1 - 0.022 14.4 0.4 0.32 10.6 0.1 2.5 3 0 0 3 3 3 0 GDP-fucose protein O-fucosyltransferase Imm1 PF14430.6 CBZ37536.1 - 0.14 12.8 0.4 26 5.5 0.0 3.2 3 0 0 3 3 3 0 Immunity protein Imm1 SNAP PF14938.6 CBZ37539.1 - 2.1e-07 30.7 14.7 3e-06 26.9 11.8 2.9 2 1 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.17 CBZ37539.1 - 0.011 15.8 11.2 0.08 13.1 0.4 5.1 3 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ37539.1 - 0.031 14.1 4.8 2.4 8.1 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ37539.1 - 0.035 14.4 0.3 0.035 14.4 0.3 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ37539.1 - 1.4 9.9 6.9 17 6.5 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat LRR_4 PF12799.7 CBZ37540.1 - 1.6e-09 37.9 21.2 0.25 11.8 0.0 6.3 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) MbeD_MobD PF04899.12 CBZ37540.1 - 5.9 7.1 7.0 1 9.6 2.5 2.0 2 0 0 2 2 2 0 MbeD/MobD like GTP_EFTU PF00009.27 CBZ37542.1 - 5.5e-43 146.8 0.2 8.8e-43 146.1 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CBZ37542.1 - 1.2e-31 109.1 1.4 1.9e-31 108.4 1.4 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CBZ37542.1 - 1.8e-14 53.5 0.0 3.4e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 CBZ37542.1 - 0.00028 20.9 0.0 0.00074 19.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CBZ37542.1 - 0.0016 18.2 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D2 PF03144.25 CBZ37542.1 - 0.0017 18.7 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 CBZ37542.1 - 0.0038 16.8 0.1 0.0078 15.8 0.1 1.4 1 0 0 1 1 1 1 Ras family Septin PF00735.18 CBZ37542.1 - 0.035 13.4 0.2 0.56 9.4 0.0 2.1 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 CBZ37542.1 - 0.047 13.2 0.3 0.093 12.2 0.3 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CBZ37542.1 - 0.068 13.1 0.0 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase DUF677 PF05055.12 CBZ37543.1 - 1.3e-05 24.3 2.5 1.5e-05 24.1 2.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF677) DUF4618 PF15397.6 CBZ37543.1 - 0.00096 18.6 6.8 0.00096 18.6 6.8 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) Phage_Mu_Gam PF07352.12 CBZ37543.1 - 0.0041 17.0 5.6 0.0041 17.0 5.6 1.8 1 1 1 2 2 2 1 Bacteriophage Mu Gam like protein FAM184 PF15665.5 CBZ37543.1 - 0.014 15.2 11.5 0.017 14.9 11.5 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B SlyX PF04102.12 CBZ37543.1 - 0.026 15.1 3.5 3.6 8.3 0.6 2.4 1 1 1 2 2 2 0 SlyX Tho2 PF11262.8 CBZ37543.1 - 0.047 12.9 6.2 0.062 12.5 6.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF1690 PF07956.11 CBZ37543.1 - 0.077 13.4 8.4 0.095 13.1 8.4 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Ax_dynein_light PF10211.9 CBZ37543.1 - 0.077 12.9 10.2 0.094 12.7 10.2 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain MPS2 PF17060.5 CBZ37543.1 - 0.08 12.2 7.2 0.091 12.0 7.2 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF641 PF04859.12 CBZ37543.1 - 0.11 12.8 6.6 0.14 12.5 6.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 CBZ37543.1 - 0.15 12.4 10.4 1.7 9.0 3.2 2.5 1 1 1 2 2 2 0 Csm1 N-terminal domain APC_N_CC PF16689.5 CBZ37543.1 - 0.22 11.6 5.7 2.7 8.1 5.1 2.2 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain FapA PF03961.13 CBZ37543.1 - 0.48 9.0 6.6 0.49 8.9 6.6 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A HALZ PF02183.18 CBZ37543.1 - 0.55 10.5 8.5 0.32 11.2 3.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper ZapB PF06005.12 CBZ37543.1 - 0.79 10.2 14.3 0.3 11.6 11.4 1.8 1 1 1 2 2 2 0 Cell division protein ZapB AAA_11 PF13086.6 CBZ37543.1 - 0.82 9.4 6.0 0.87 9.3 6.0 1.1 1 0 0 1 1 1 0 AAA domain DivIC PF04977.15 CBZ37543.1 - 0.96 9.3 11.2 6.4 6.6 2.5 3.0 2 1 1 3 3 3 0 Septum formation initiator FAM76 PF16046.5 CBZ37543.1 - 1.6 8.0 9.3 1.5 8.1 8.7 1.3 1 1 0 1 1 1 0 FAM76 protein FlaC_arch PF05377.11 CBZ37543.1 - 1.8 9.0 8.3 1.9 9.0 3.5 2.4 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DUF4446 PF14584.6 CBZ37543.1 - 3 7.8 8.5 1.7 8.6 5.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 CBZ37543.1 - 5.5 6.1 6.0 6.1 6.0 6.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein RRF PF01765.19 CBZ37543.1 - 6.6 6.7 13.0 1.1 9.1 6.5 2.0 1 1 1 2 2 2 0 Ribosome recycling factor LapA_dom PF06305.11 CBZ37543.1 - 8.4 6.3 8.7 35 4.3 2.2 2.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Titin_Z PF09042.11 CBZ37544.1 - 0.35 10.9 5.3 6.6 6.8 1.9 3.1 2 0 0 2 2 2 0 Titin Z DinB_2 PF12867.7 CBZ37544.1 - 2.4 8.7 5.8 0.71 10.4 0.9 2.8 3 0 0 3 3 3 0 DinB superfamily NMO PF03060.15 CBZ37546.1 - 2.8e-60 204.5 2.8 1.9e-39 136.0 2.7 2.0 1 1 1 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 CBZ37546.1 - 1.6e-10 40.5 0.3 1.1e-05 24.6 1.1 2.4 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CBZ37546.1 - 7.6e-09 35.1 0.8 1.3e-08 34.3 0.8 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 CBZ37546.1 - 7.9e-06 25.3 0.1 1.6e-05 24.3 0.1 1.5 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.14 CBZ37546.1 - 5.2e-05 22.7 1.0 8.6e-05 22.0 1.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 CBZ37546.1 - 0.00059 19.1 0.3 0.001 18.3 0.3 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Peripla_BP_6 PF13458.6 CBZ37546.1 - 0.018 14.7 0.8 0.32 10.6 0.8 2.3 1 1 2 3 3 3 0 Periplasmic binding protein ZnuA PF01297.17 CBZ37546.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic COG5 PF10392.9 CBZ37547.1 - 1 9.5 4.4 17 5.6 0.3 2.8 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF1664 PF07889.12 CBZ37547.1 - 7.6 6.6 13.1 0.23 11.5 0.8 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FAA_hydro_N_2 PF18288.1 CBZ37548.1 - 0.82 10.1 5.4 28 5.2 0.0 4.2 3 1 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 DUF1818 PF08848.11 CBZ37548.1 - 1.1 9.4 5.5 0.38 10.9 0.6 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF1818) Sec20 PF03908.13 CBZ37548.1 - 2.9 7.9 8.0 2.7 8.0 1.8 3.1 1 1 2 3 3 3 0 Sec20 Spc7 PF08317.11 CBZ37548.1 - 4.3 6.1 40.5 0.18 10.7 20.7 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein Nup88 PF10168.9 CBZ37548.1 - 8.3 4.1 18.7 15 3.2 18.7 1.4 1 0 0 1 1 1 0 Nuclear pore component LRR_8 PF13855.6 CBZ37549.1 - 0.0038 17.0 0.5 0.2 11.4 0.0 3.1 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 CBZ37549.1 - 0.35 11.0 8.5 5.4 7.3 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeat JAB PF01398.21 CBZ37550.1 - 7.6e-28 96.9 0.0 1.4e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CBZ37550.1 - 1.6e-08 34.3 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MitMem_reg PF13012.6 CBZ37550.1 - 0.0022 18.4 0.2 0.0053 17.2 0.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function ABC_tran PF00005.27 CBZ37552.1 - 3e-39 134.7 0.0 5.3e-22 78.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CBZ37552.1 - 1.2e-35 123.5 21.4 5e-21 75.6 6.4 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 CBZ37552.1 - 1e-08 34.9 0.8 0.00042 19.8 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CBZ37552.1 - 1.3e-05 25.2 0.3 0.73 9.6 0.0 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CBZ37552.1 - 2e-05 24.6 0.2 0.015 15.3 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ37552.1 - 3.7e-05 23.7 0.1 0.062 13.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CBZ37552.1 - 0.00021 21.7 2.9 0.011 16.1 0.0 3.8 2 1 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 CBZ37552.1 - 0.00022 21.3 0.3 0.99 9.4 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AAA_29 PF13555.6 CBZ37552.1 - 0.00058 19.5 0.1 0.4 10.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 CBZ37552.1 - 0.0032 17.9 0.0 2.2 8.7 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ37552.1 - 0.0041 17.4 0.1 0.19 12.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.16 CBZ37552.1 - 0.0086 15.4 1.1 1.2 8.4 0.1 2.4 2 0 0 2 2 2 1 AIG1 family AAA_25 PF13481.6 CBZ37552.1 - 0.0091 15.6 0.1 0.14 11.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CBZ37552.1 - 0.017 15.6 0.4 4.1 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CBZ37552.1 - 0.055 13.9 0.1 4.6 7.7 0.0 3.1 3 0 0 3 3 3 0 RNA helicase ATPase_2 PF01637.18 CBZ37552.1 - 0.065 13.1 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Transposase_20 PF02371.16 CBZ37552.1 - 0.075 13.4 0.5 0.36 11.2 0.1 2.4 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family Rrn6 PF10214.9 CBZ37552.1 - 0.16 10.4 2.4 0.27 9.7 2.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF5539 PF17693.1 CBZ37552.1 - 0.64 9.6 8.6 0.1 12.2 0.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5539) MT PF12777.7 CBZ37553.1 - 0.0034 16.5 3.8 0.011 14.8 3.8 1.8 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor FTA4 PF13093.6 CBZ37554.1 - 0.17 11.7 0.1 0.17 11.7 0.1 3.9 4 1 0 4 4 4 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Spc42p PF11544.8 CBZ37554.1 - 1.8 8.6 9.9 7.3 6.7 0.0 3.9 3 1 0 3 3 3 0 Spindle pole body component Spc42p MT PF12777.7 CBZ37555.1 - 0.0013 17.8 3.0 0.0021 17.1 0.7 1.9 1 1 0 2 2 2 1 Microtubule-binding stalk of dynein motor HrpB7 PF09486.10 CBZ37555.1 - 0.16 12.4 4.9 1.7 9.1 0.9 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF2039 PF10217.9 CBZ37556.1 - 2.8e-22 78.9 22.8 4.4e-22 78.2 22.8 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) Tankyrase_bdg_C PF15327.6 CBZ37556.1 - 0.043 14.3 2.5 0.073 13.5 2.5 1.4 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain Cript PF10235.9 CBZ37556.1 - 3.6 8.2 16.6 13 6.4 16.7 1.9 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT Transmemb_17 PF09799.9 CBZ37557.1 - 1.3e-19 70.7 9.7 1.9e-19 70.2 9.7 1.2 1 0 0 1 1 1 1 Predicted membrane protein DUF2070 PF09843.9 CBZ37557.1 - 3.3 5.9 10.9 3.8 5.7 10.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Acetyltransf_16 PF05301.11 CBZ37558.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 YqeY PF09424.10 CBZ37558.1 - 0.13 12.3 0.0 0.43 10.7 0.0 1.9 1 1 0 1 1 1 0 Yqey-like protein Sod_Fe_C PF02777.18 CBZ37559.1 - 0.0036 17.4 0.0 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Tcp10_C PF07202.13 CBZ37559.1 - 0.018 15.0 0.1 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 T-complex protein 10 C-terminus DUF3767 PF12597.8 CBZ37559.1 - 0.05 13.4 0.5 0.12 12.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) SpoIIE PF07228.12 CBZ37560.1 - 9.3e-09 35.5 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CBZ37560.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CBZ37560.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C CBF PF03914.17 CBZ37561.1 - 1.9e-27 96.4 0.7 3e-27 95.7 0.7 1.3 1 0 0 1 1 1 1 CBF/Mak21 family DUF4844 PF16133.5 CBZ37562.1 - 0.03 14.9 0.1 1.4 9.5 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4844) NAD_binding_10 PF13460.6 CBZ37563.1 - 1.9e-06 27.9 0.0 0.0023 17.9 0.1 2.3 2 0 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 CBZ37563.1 - 0.00068 19.3 0.1 0.0034 17.0 0.1 1.9 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.20 CBZ37563.1 - 0.001 19.1 0.1 0.0019 18.3 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CBZ37563.1 - 0.0077 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 CBZ37563.1 - 0.09 12.2 0.0 0.72 9.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CBZ37563.1 - 0.13 11.7 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 CBZ37563.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Metallophos PF00149.28 CBZ37565.1 - 4.1e-28 99.3 0.0 5.3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ37565.1 - 6.9e-14 52.0 1.3 1.2e-13 51.3 1.3 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CBZ37566.1 - 1.6e-16 61.5 0.1 2e-16 61.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ37566.1 - 1.2e-13 51.2 0.4 1.7e-13 50.8 0.4 1.2 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos PF00149.28 CBZ37567.1 - 4.6e-18 66.5 0.1 5.7e-18 66.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ37567.1 - 6.2e-15 55.4 1.9 8.7e-15 54.9 1.9 1.2 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PAH PF02671.21 CBZ37567.1 - 0.13 12.4 1.1 0.31 11.2 0.0 2.1 3 0 0 3 3 3 0 Paired amphipathic helix repeat Pcc1 PF09341.10 CBZ37568.1 - 2.5e-10 40.4 0.1 3.9e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF4232 PF14016.6 CBZ37568.1 - 0.054 13.6 1.0 1.6 8.8 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4232) EF1_GNE PF00736.19 CBZ37569.1 - 3.3e-26 91.3 1.1 5.7e-26 90.5 1.1 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain GST_C_2 PF13410.6 CBZ37569.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CBZ37569.1 - 0.1 12.4 0.2 0.38 10.6 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain HTH_1 PF00126.27 CBZ37569.1 - 0.12 12.4 0.1 9.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family Stm1_N PF09598.10 CBZ37569.1 - 0.92 10.4 9.0 1.9 9.4 2.3 2.5 2 0 0 2 2 2 0 Stm1 DUF3275 PF11679.8 CBZ37569.1 - 3.9 7.4 6.9 6.9 6.6 6.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) GST_C_2 PF13410.6 CBZ37570.1 - 0.0029 17.6 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AsnC_trans_reg PF01037.21 CBZ37570.1 - 0.085 12.8 0.0 0.13 12.3 0.0 1.3 1 1 0 1 1 1 0 Lrp/AsnC ligand binding domain Metallophos PF00149.28 CBZ37571.1 - 2.5e-32 113.0 0.0 3.1e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CBZ37571.1 - 1.7e-05 25.2 0.0 3.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Ribosomal_L13 PF00572.18 CBZ37572.1 - 0.13 12.5 0.8 1.4 9.2 0.8 2.1 1 1 0 1 1 1 0 Ribosomal protein L13 DARPP-32 PF05395.12 CBZ37573.1 - 0.079 13.2 3.8 0.19 11.9 3.8 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 RNA_pol_Rpb6 PF01192.22 CBZ37575.1 - 4.4e-14 52.1 1.5 5.7e-14 51.8 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb6 UQ_con PF00179.26 CBZ37576.1 - 1.2e-16 60.6 0.0 2e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_E PF14462.6 CBZ37576.1 - 0.069 13.0 0.4 8.3 6.2 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic E2 family E DUF2046 PF09755.9 CBZ37578.1 - 0.12 11.5 6.2 0.12 11.6 3.3 2.1 2 1 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) TSP_NTD PF17804.1 CBZ37578.1 - 0.19 12.0 0.3 0.3 11.3 0.3 1.2 1 0 0 1 1 1 0 Tail specific protease N-terminal domain SR-25 PF10500.9 CBZ37578.1 - 1.9 8.0 12.8 4 7.0 12.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-Tim10_DDP PF02953.15 CBZ37579.1 - 0.01 15.4 0.8 0.041 13.5 0.0 2.0 2 0 0 2 2 2 0 Tim10/DDP family zinc finger Pkinase PF00069.25 CBZ37580.1 - 9.7e-41 139.9 0.0 3.2e-30 105.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37580.1 - 5.8e-19 68.4 0.0 2.6e-14 53.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CBZ37580.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CBZ37580.1 - 0.29 11.0 2.9 0.83 9.5 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Rhodanese PF00581.20 CBZ37581.1 - 7.3e-08 32.9 0.0 0.0054 17.2 0.0 3.3 2 1 0 2 2 2 2 Rhodanese-like domain Amastin PF07344.11 CBZ37582.1 - 3.4e-58 195.9 5.0 4.2e-58 195.6 5.0 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.6 CBZ37582.1 - 0.012 15.4 0.3 0.012 15.4 0.3 1.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF829 PF05705.14 CBZ37582.1 - 0.21 11.4 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) PMP22_Claudin PF00822.20 CBZ37582.1 - 0.4 10.5 8.3 0.086 12.7 4.1 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Amastin PF07344.11 CBZ37583.1 - 5.7e-50 169.2 8.1 6.5e-50 169.0 8.1 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein Claudin_2 PF13903.6 CBZ37583.1 - 0.0013 18.6 0.6 0.0013 18.6 0.6 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction UNC-50 PF05216.13 CBZ37583.1 - 0.12 11.9 8.5 0.17 11.4 8.5 1.1 1 0 0 1 1 1 0 UNC-50 family SUR7 PF06687.12 CBZ37583.1 - 0.79 9.3 20.6 0.4 10.3 11.6 2.3 1 1 1 2 2 2 0 SUR7/PalI family Amastin PF07344.11 CBZ37584.1 - 1.1e-50 171.5 10.8 1.3e-50 171.3 10.8 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein DUF4064 PF13273.6 CBZ37584.1 - 0.055 13.7 0.0 0.055 13.7 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) SUR7 PF06687.12 CBZ37584.1 - 0.19 11.3 22.4 0.38 10.4 9.1 3.1 2 1 1 3 3 3 0 SUR7/PalI family Amastin PF07344.11 CBZ37585.1 - 9.5e-40 136.0 11.3 1.1e-39 135.7 11.3 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein ABC_membrane PF00664.23 CBZ37586.1 - 4.5e-130 433.2 18.4 6.8e-72 242.4 8.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CBZ37586.1 - 7.7e-67 224.0 0.0 5.1e-32 111.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CBZ37586.1 - 4.5e-12 45.9 0.0 1.7e-05 24.4 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CBZ37586.1 - 5.5e-06 26.9 0.1 0.056 13.8 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CBZ37586.1 - 2.9e-05 24.3 0.7 0.026 14.8 0.0 3.6 2 2 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBZ37586.1 - 3.1e-05 23.9 0.0 0.4 10.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 CBZ37586.1 - 7.4e-05 22.1 0.0 0.15 11.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.29 CBZ37586.1 - 7.9e-05 23.1 0.0 2.1 8.8 0.1 3.6 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CBZ37586.1 - 0.00077 19.1 0.7 1.4 8.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 CBZ37586.1 - 0.0012 17.8 0.0 0.16 10.7 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_5 PF07728.14 CBZ37586.1 - 0.0031 17.5 0.0 0.075 13.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 CBZ37586.1 - 0.0032 17.1 0.0 0.88 9.2 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 CBZ37586.1 - 0.004 17.4 4.5 6.4 7.1 0.2 4.9 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 CBZ37586.1 - 0.0062 16.1 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region RNA_helicase PF00910.22 CBZ37586.1 - 0.021 15.2 0.3 5.8 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 CBZ37586.1 - 0.025 13.7 0.2 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MoaE PF02391.17 CBZ37586.1 - 0.03 14.6 0.3 6.6 7.0 0.0 3.2 3 0 0 3 3 3 0 MoaE protein AAA_23 PF13476.6 CBZ37586.1 - 0.032 14.7 0.1 0.46 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2852 PF11014.8 CBZ37586.1 - 0.032 14.4 0.9 8.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) G-alpha PF00503.20 CBZ37586.1 - 0.034 13.3 0.0 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA_15 PF13175.6 CBZ37586.1 - 0.036 13.8 0.0 2.1 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 CBZ37586.1 - 0.064 13.0 0.3 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Abhydrolase_9_N PF15420.6 CBZ37586.1 - 0.079 13.0 9.2 0.029 14.4 1.1 3.3 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Rad17 PF03215.15 CBZ37586.1 - 0.11 12.5 0.4 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 CBZ37586.1 - 0.14 11.9 0.2 10 5.8 0.0 3.0 3 1 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 CBZ37586.1 - 0.22 11.6 0.8 16 5.6 0.0 3.4 4 0 0 4 4 3 0 50S ribosome-binding GTPase Myosin_head PF00063.21 CBZ37587.1 - 3.7e-208 693.0 0.0 4.1e-125 418.6 0.0 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) Myosin_TH1 PF06017.13 CBZ37587.1 - 1.9e-07 30.9 0.0 0.029 14.1 0.0 3.2 3 0 0 3 3 3 2 Unconventional myosin tail, actin- and lipid-binding FYVE PF01363.21 CBZ37587.1 - 2e-05 24.6 7.5 5.2e-05 23.3 7.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger AAA_16 PF13191.6 CBZ37587.1 - 0.021 15.2 2.6 0.039 14.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 CBZ37587.1 - 0.16 12.5 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 CBZ37587.1 - 0.23 11.2 8.4 21 4.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain EPO_TPO PF00758.18 CBZ37588.1 - 0.18 11.9 2.9 7.4 6.6 0.0 2.9 3 0 0 3 3 3 0 Erythropoietin/thrombopoietin N2227 PF07942.12 CBZ37589.1 - 2.3e-93 312.4 0.0 2.8e-93 312.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein EF-hand_7 PF13499.6 CBZ37590.1 - 1.6e-09 38.1 0.0 2.6e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CBZ37590.1 - 5.3e-09 35.8 0.1 9.6e-09 35.0 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ37590.1 - 2.1e-06 26.8 0.1 0.00061 19.2 0.2 3.0 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 CBZ37590.1 - 4.2e-05 23.2 0.1 0.035 14.0 0.1 3.0 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBZ37590.1 - 0.00052 19.4 1.2 0.0013 18.1 0.1 2.2 2 0 0 2 2 2 1 EF hand Ribosomal_60s PF00428.19 CBZ37590.1 - 0.73 10.5 0.1 0.73 10.5 0.1 2.5 2 1 0 2 2 2 0 60s Acidic ribosomal protein UPRTase PF14681.6 CBZ37591.1 - 1.9e-70 236.5 0.0 2.3e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CBZ37591.1 - 3.4e-06 26.7 0.0 5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SET PF00856.28 CBZ37592.1 - 2.1e-15 57.6 0.0 7.3e-15 55.8 0.0 2.0 2 1 0 2 2 2 1 SET domain TPR_2 PF07719.17 CBZ37592.1 - 5.2e-07 29.3 10.2 0.00052 19.9 0.3 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ37592.1 - 0.0034 17.6 7.9 0.028 14.7 0.6 4.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ37592.1 - 0.011 15.6 0.5 0.011 15.6 0.5 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ37592.1 - 0.012 16.3 6.0 0.14 13.1 0.1 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ37592.1 - 0.053 13.7 2.0 0.42 11.0 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ37592.1 - 0.22 11.4 2.9 1.2 9.1 0.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ37592.1 - 0.4 10.8 3.1 4.7 7.5 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M41 PF01434.18 CBZ37593.1 - 1e-39 136.4 0.0 1.6e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBZ37593.1 - 3.4e-39 134.3 0.0 5.9e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ37593.1 - 2.1e-10 40.3 0.0 5.5e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CBZ37593.1 - 0.00024 21.3 0.0 0.00051 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBZ37593.1 - 0.00024 21.5 0.0 0.11 12.9 0.1 2.8 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CBZ37593.1 - 0.00031 20.5 0.0 0.001 18.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CBZ37593.1 - 0.0024 17.1 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CBZ37593.1 - 0.0065 16.7 0.0 0.4 11.0 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ37593.1 - 0.0089 16.0 1.2 0.15 12.0 0.3 3.2 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CBZ37593.1 - 0.019 14.5 0.2 3.3 7.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 CBZ37593.1 - 0.023 14.7 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBZ37593.1 - 0.047 13.4 0.1 0.094 12.4 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CBZ37593.1 - 0.052 12.9 0.1 0.15 11.4 0.1 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CBZ37593.1 - 0.11 13.0 0.0 0.78 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Lipase_3 PF01764.25 CBZ37594.1 - 1.5e-07 31.4 0.0 3.2e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CBZ37594.1 - 7.4e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 CBZ37594.1 - 0.0011 18.6 0.1 0.0044 16.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 CBZ37594.1 - 0.0029 18.3 0.1 0.0029 18.3 0.1 3.0 3 1 0 3 3 3 1 Alpha/beta hydrolase family TMEM43 PF07787.12 CBZ37594.1 - 0.012 15.0 2.6 0.031 13.7 2.6 1.7 1 0 0 1 1 1 0 Transmembrane protein 43 Thioesterase PF00975.20 CBZ37594.1 - 0.04 14.0 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 CBZ37594.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CBZ37594.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1409 PF07197.12 CBZ37594.1 - 0.15 11.9 0.1 28 4.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) PGAP1 PF07819.13 CBZ37594.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Pox_A14 PF05767.12 CBZ37594.1 - 0.38 10.9 3.6 0.32 11.2 0.7 2.4 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Amastin PF07344.11 CBZ37595.1 - 3e-54 183.1 16.6 3.7e-54 182.8 16.6 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein Acyltransferase PF01553.21 CBZ37597.1 - 2.4e-18 66.0 0.0 6.3e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase SBDS PF01172.18 CBZ37599.1 - 1e-24 86.4 0.4 1.8e-24 85.6 0.4 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CBZ37599.1 - 5.1e-24 84.5 0.0 1.2e-23 83.3 0.0 1.7 2 0 0 2 2 2 1 SBDS protein C-terminal domain CH_2 PF06294.11 CBZ37600.1 - 1.2e-30 105.4 0.0 2.3e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 CBZ37600.1 - 5.9e-19 67.7 0.0 1e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain Csm1_N PF18504.1 CBZ37600.1 - 0.057 13.8 2.3 0.057 13.8 2.3 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain CH PF00307.31 CBZ37600.1 - 0.079 13.1 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Calponin homology (CH) domain TMF_DNA_bd PF12329.8 CBZ37600.1 - 0.18 11.8 5.0 0.17 11.9 2.3 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 CBZ37600.1 - 0.28 11.1 2.5 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 CBZ37600.1 - 2.6 8.2 5.1 4.8 7.4 4.9 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Dus PF01207.17 CBZ37602.1 - 3.5e-53 180.7 0.0 8.9e-52 176.1 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) BMC PF00936.19 CBZ37602.1 - 0.0052 16.7 0.6 0.035 14.1 0.0 2.3 2 0 0 2 2 2 1 BMC domain ThiG PF05690.14 CBZ37602.1 - 0.008 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 CBZ37602.1 - 0.0098 15.4 0.0 0.033 13.7 0.0 1.8 3 0 0 3 3 3 1 Histidine biosynthesis protein DUF167 PF02594.16 CBZ37604.1 - 3.9e-13 49.3 0.1 4.8e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised ACR, YggU family COG1872 Cnn_1N PF07989.11 CBZ37606.1 - 0.004 17.3 4.7 0.004 17.3 4.7 6.9 2 2 2 6 6 6 2 Centrosomin N-terminal motif 1 Stc1 PF12898.7 CBZ37606.1 - 0.61 10.7 7.7 0.082 13.5 1.0 3.0 2 0 0 2 2 2 0 Stc1 domain Glycophorin_A PF01102.18 CBZ37608.1 - 0.17 12.1 0.1 0.38 11.0 0.1 1.6 1 0 0 1 1 1 0 Glycophorin A HA2 PF04408.23 CBZ37609.1 - 1.7e-13 50.8 0.0 5.4e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ37609.1 - 2.1e-12 47.4 0.0 1.4e-11 44.7 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ37609.1 - 1e-10 41.7 0.1 2.5e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CBZ37609.1 - 0.00024 21.4 0.3 0.0045 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain dsrm PF00035.26 CBZ37609.1 - 0.0034 18.1 0.7 0.096 13.4 0.2 2.8 3 0 0 3 3 3 1 Double-stranded RNA binding motif AAA_22 PF13401.6 CBZ37609.1 - 0.0061 16.8 0.1 0.018 15.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBZ37609.1 - 0.047 12.7 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 CBZ37609.1 - 0.051 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 CBZ37609.1 - 0.22 11.7 1.3 17 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain F-box PF00646.33 CBZ37611.1 - 0.046 13.6 0.5 0.085 12.8 0.5 1.5 1 0 0 1 1 1 0 F-box domain Exo_endo_phos PF03372.23 CBZ37612.1 - 7.1e-05 22.4 0.0 0.00018 21.1 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YabA PF06156.13 CBZ37613.1 - 0.025 15.2 3.2 0.028 15.0 0.8 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Shugoshin_N PF07558.11 CBZ37613.1 - 0.045 13.6 2.8 0.12 12.3 1.4 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region TolA_bind_tri PF16331.5 CBZ37613.1 - 0.19 11.8 8.9 6 7.0 0.1 2.8 2 0 0 2 2 2 0 TolA binding protein trimerisation Vps51 PF08700.11 CBZ37613.1 - 0.4 10.8 2.3 0.59 10.2 0.9 2.0 2 0 0 2 2 2 0 Vps51/Vps67 HALZ PF02183.18 CBZ37613.1 - 2.4 8.4 3.9 5.3 7.4 0.9 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.15 CBZ37613.1 - 3.9 7.3 6.1 15 5.4 1.5 2.6 2 0 0 2 2 2 0 Septum formation initiator DNA_pol_A_exo1 PF01612.20 CBZ37614.1 - 4.6e-13 49.2 0.1 2.3e-12 47.0 0.0 2.1 2 1 1 3 3 3 1 3'-5' exonuclease zf-CCCH PF00642.24 CBZ37614.1 - 0.013 15.4 0.2 0.03 14.2 0.2 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBZ37614.1 - 0.031 15.0 0.5 0.13 13.0 0.0 2.3 2 0 0 2 2 2 0 Torus domain zf-RRN7 PF11781.8 CBZ37614.1 - 0.07 12.8 0.4 0.56 10.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TPR_15 PF13429.6 CBZ37615.1 - 0.0046 16.2 0.2 0.0054 16.0 0.2 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat NIF PF03031.18 CBZ37616.1 - 9.3e-31 106.7 0.1 1.3e-28 99.8 0.1 3.0 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase Ntox34 PF15606.6 CBZ37616.1 - 0.0085 16.2 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial toxin 34 Sds3 PF08598.11 CBZ37616.1 - 0.18 11.8 0.8 1.9 8.5 0.1 2.1 2 0 0 2 2 2 0 Sds3-like Bac_chlorC PF02043.17 CBZ37616.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriochlorophyll C binding protein DNA_pol_A PF00476.20 CBZ37617.1 - 1.9e-94 316.8 0.0 8.4e-83 278.5 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family A Piezo_RRas_bdg PF12166.8 CBZ37618.1 - 5e-88 296.2 0.0 6.5e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain LRR_6 PF13516.6 CBZ37620.1 - 4.1e-05 23.3 1.3 10 6.4 0.0 6.2 6 0 0 6 6 6 2 Leucine Rich repeat MFS18 PF17352.2 CBZ37620.1 - 2.8 8.4 10.4 4.4 7.7 0.1 2.9 1 1 1 2 2 2 0 Male Flower Specific protein 18 OsmC PF02566.19 CBZ37621.1 - 1.3e-06 28.8 0.4 2.5e-06 27.9 0.4 1.5 1 0 0 1 1 1 1 OsmC-like protein BCS1_N PF08740.11 CBZ37624.1 - 7.5e-30 104.3 3.6 1.2e-29 103.7 3.6 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CBZ37624.1 - 2.1e-19 70.2 0.0 4.2e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CBZ37624.1 - 0.00064 20.2 0.3 0.012 16.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CBZ37624.1 - 0.0011 18.9 0.2 0.01 15.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CBZ37624.1 - 0.0012 18.7 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CBZ37624.1 - 0.003 17.5 0.0 0.017 15.1 0.0 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 CBZ37624.1 - 0.0037 17.8 0.0 0.0085 16.6 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_11 PF13086.6 CBZ37624.1 - 0.0041 17.0 0.0 0.0071 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CBZ37624.1 - 0.0091 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.13 CBZ37624.1 - 0.01 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 CBZ37624.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ37624.1 - 0.033 14.1 0.1 0.19 11.6 0.0 2.3 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 CBZ37624.1 - 0.037 14.6 0.0 0.083 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CBZ37624.1 - 0.046 14.0 0.1 0.41 10.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CBZ37624.1 - 0.13 12.1 0.0 9.6 6.0 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 CBZ37624.1 - 0.17 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Syntaxin PF00804.25 CBZ37626.1 - 0.0073 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Syntaxin Filament PF00038.21 CBZ37626.1 - 0.041 13.5 1.1 0.072 12.7 1.1 1.4 1 0 0 1 1 1 0 Intermediate filament protein Nup188 PF10487.9 CBZ37627.1 - 0.00081 17.5 0.3 0.0024 15.9 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 Spc7 PF08317.11 CBZ37628.1 - 1.1 8.1 12.8 1.6 7.6 12.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 CBZ37628.1 - 1.9 8.6 7.6 5.2 7.1 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_33 PF13671.6 CBZ37628.1 - 7.8 6.6 8.6 4 7.6 6.1 1.7 2 1 0 2 2 2 0 AAA domain Atg14 PF10186.9 CBZ37628.1 - 9.7 5.2 13.1 18 4.3 13.1 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 VPS13 PF16908.5 CBZ37630.1 - 3e-35 122.1 0.0 4.9e-34 118.2 0.0 2.7 2 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CBZ37630.1 - 6.2e-27 94.0 0.1 1.8e-26 92.5 0.1 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 SHR-BD PF06650.12 CBZ37630.1 - 1.2e-13 51.1 0.0 1.1e-08 34.8 0.0 3.4 3 0 0 3 3 3 3 SHR-binding domain of vacuolar-sorting associated protein 13 SPK PF04435.18 CBZ37631.1 - 0.096 13.1 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF545) DUF1143 PF06608.11 CBZ37632.1 - 0.031 14.3 0.1 0.091 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1143) PTEN_C2 PF10409.9 CBZ37633.1 - 1.5e-10 41.0 0.0 2.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 CBZ37633.1 - 2.5e-08 33.8 0.1 5.3e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ37633.1 - 0.00015 21.5 0.1 0.00032 20.4 0.1 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBZ37633.1 - 0.0016 18.5 0.0 0.0032 17.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CBZ37633.1 - 0.017 15.2 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate C2 PF00168.30 CBZ37634.1 - 0.042 14.1 0.0 4.8 7.5 0.0 3.2 3 1 0 3 3 3 0 C2 domain R3H-assoc PF13902.6 CBZ37635.1 - 2.9e-18 66.6 0.1 6.9e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 CBZ37635.1 - 0.0066 16.4 0.0 0.022 14.7 0.0 1.9 1 0 0 1 1 1 1 R3H domain PPR PF01535.20 CBZ37636.1 - 0.072 13.4 0.0 17 6.0 0.0 2.9 2 0 0 2 2 2 0 PPR repeat PPR_2 PF13041.6 CBZ37636.1 - 0.084 13.1 0.0 21 5.4 0.0 3.3 4 0 0 4 4 4 0 PPR repeat family EAP30 PF04157.16 CBZ37637.1 - 1e-65 221.3 1.9 1.5e-65 220.8 1.9 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family DUF3995 PF13160.6 CBZ37639.1 - 0.87 10.0 4.0 2.8 8.3 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) DUF3808 PF10300.9 CBZ37640.1 - 1.2e-42 146.3 1.0 2.2e-42 145.4 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) DUF4094 PF13334.6 CBZ37641.1 - 0.0052 17.2 0.2 0.024 15.1 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) p25-alpha PF05517.12 CBZ37642.1 - 4.7e-34 117.8 3.5 5.4e-34 117.6 3.5 1.0 1 0 0 1 1 1 1 p25-alpha Spo0A_C PF08769.11 CBZ37642.1 - 0.025 14.6 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal SCP-1 PF05483.12 CBZ37642.1 - 0.054 11.5 0.1 0.064 11.3 0.1 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) p25-alpha PF05517.12 CBZ37643.1 - 4.7e-34 117.8 3.5 5.4e-34 117.6 3.5 1.0 1 0 0 1 1 1 1 p25-alpha Spo0A_C PF08769.11 CBZ37643.1 - 0.025 14.6 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal SCP-1 PF05483.12 CBZ37643.1 - 0.054 11.5 0.1 0.064 11.3 0.1 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Kinesin PF00225.23 CBZ37644.1 - 3.2e-88 295.8 0.0 4.4e-88 295.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ37644.1 - 5.6e-23 81.5 0.7 8e-20 71.3 0.0 2.8 2 1 0 2 2 2 1 Microtubule binding TrwB_AAD_bind PF10412.9 CBZ37644.1 - 0.003 16.5 0.0 0.0057 15.6 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 CBZ37644.1 - 0.014 15.8 0.0 0.065 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain DUF4140 PF13600.6 CBZ37644.1 - 0.035 14.5 6.2 0.13 12.7 0.6 3.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) HsbA PF12296.8 CBZ37644.1 - 0.13 12.7 1.1 8.5 6.8 0.3 3.1 3 0 0 3 3 3 0 Hydrophobic surface binding protein A Kinesin_assoc PF16183.5 CBZ37644.1 - 0.85 9.7 2.7 1.3 9.2 0.3 2.5 2 1 0 2 2 2 0 Kinesin-associated DivIC PF04977.15 CBZ37644.1 - 1.8 8.4 6.0 11 5.9 0.0 3.6 3 0 0 3 3 3 0 Septum formation initiator KASH_CCD PF14662.6 CBZ37644.1 - 3.1 7.6 7.2 0.68 9.7 0.9 2.7 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH DEAD PF00270.29 CBZ37645.1 - 1.8e-05 24.6 0.0 2.9e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ37645.1 - 3.2e-05 24.2 0.0 0.0003 21.1 0.0 2.7 3 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_7 PF12775.7 CBZ37645.1 - 0.0082 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region UQ_con PF00179.26 CBZ37646.1 - 8.4e-22 77.3 0.0 9.6e-22 77.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Amastin PF07344.11 CBZ37647.1 - 1.1e-56 191.0 11.1 1.8e-56 190.3 11.1 1.3 1 0 0 1 1 1 1 Amastin surface glycoprotein Fz PF01392.22 CBZ37647.1 - 0.38 11.4 4.8 0.087 13.4 1.2 1.7 2 0 0 2 2 2 0 Fz domain SRTM1 PF15872.5 CBZ37647.1 - 0.96 9.6 8.8 0.94 9.7 1.1 2.5 1 1 1 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 Amastin PF07344.11 CBZ37648.1 - 1.1e-47 161.8 9.5 1.3e-47 161.5 9.5 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CBZ37648.1 - 0.00074 19.4 6.9 0.0011 18.9 6.9 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin family DUF973 PF06157.11 CBZ37648.1 - 0.088 11.8 5.5 0.085 11.9 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF973) Claudin_2 PF13903.6 CBZ37648.1 - 0.24 11.2 15.5 0.012 15.3 9.4 1.8 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3273 PF11677.8 CBZ37648.1 - 0.57 9.4 9.8 0.054 12.8 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3273) DUF2530 PF10745.9 CBZ37648.1 - 1.7 8.9 9.5 7.1 6.9 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) SP_C-Propep PF08999.10 CBZ37648.1 - 2.9 7.8 13.0 2 8.3 0.3 3.3 2 1 1 3 3 3 0 Surfactant protein C, N terminal propeptide DUF805 PF05656.14 CBZ37648.1 - 6.4 7.2 9.6 1.8 9.0 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Amastin PF07344.11 CBZ37649.1 - 9.7e-53 178.2 15.7 1.9e-52 177.2 15.7 1.4 1 0 0 1 1 1 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ37651.1 - 7.1e-52 175.4 13.1 8.7e-52 175.1 13.1 1.1 1 0 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CBZ37651.1 - 0.041 13.8 11.3 0.066 13.1 11.3 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Claudin_2 PF13903.6 CBZ37651.1 - 0.44 10.3 11.9 0.012 15.4 4.2 2.1 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction CrgA PF06781.12 CBZ37651.1 - 0.92 9.6 3.6 1.3 9.1 1.6 2.4 2 0 0 2 2 2 0 Cell division protein CrgA Zeta_toxin PF06414.12 CBZ37652.1 - 1.8e-09 37.2 0.0 5.8e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin Thioredoxin PF00085.20 CBZ37652.1 - 0.089 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin AAA_33 PF13671.6 CBZ37652.1 - 0.095 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Peptidase_C15 PF01470.17 CBZ37653.1 - 9.6e-10 39.0 0.4 0.00093 19.4 0.1 2.3 2 0 0 2 2 2 2 Pyroglutamyl peptidase DUF4075 PF13294.6 CBZ37653.1 - 0.18 12.0 0.4 0.63 10.2 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4075) RCC1 PF00415.18 CBZ37655.1 - 3.7e-23 81.9 1.2 6.4e-08 33.1 0.1 4.7 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ37655.1 - 2.1e-18 65.6 13.2 2.8e-10 39.7 1.7 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 CBZ37656.1 - 0.0011 18.6 45.2 0.013 15.2 0.8 7.3 7 0 0 7 7 7 6 IQ calmodulin-binding motif DEAD PF00270.29 CBZ37658.1 - 5.4e-45 153.3 0.0 1.4e-44 152.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ37658.1 - 3.7e-23 82.0 0.0 8.7e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CBZ37658.1 - 1.3e-10 41.3 3.7 3.6e-10 40.0 3.7 1.7 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 CBZ37658.1 - 0.00032 20.7 0.0 0.00087 19.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ37658.1 - 0.13 12.5 0.2 0.95 9.7 0.2 2.5 1 1 0 1 1 1 0 AAA domain FtsX PF02687.21 CBZ37660.1 - 1.5e-10 41.4 8.0 1.5e-10 41.4 8.0 6.6 5 1 1 6 6 6 2 FtsX-like permease family Fez1 PF06818.15 CBZ37661.1 - 0.0027 18.2 16.9 0.067 13.6 9.6 2.8 1 1 1 2 2 2 2 Fez1 LAT PF15234.6 CBZ37661.1 - 0.019 14.7 2.0 4.2 7.0 0.1 2.6 2 0 0 2 2 2 0 Linker for activation of T-cells DUF724 PF05266.14 CBZ37661.1 - 0.09 12.6 3.5 0.21 11.4 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Mlf1IP PF10248.9 CBZ37661.1 - 0.16 11.9 1.3 0.31 11.0 1.3 1.4 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein MIP-T3_C PF17749.1 CBZ37661.1 - 0.25 11.3 7.3 0.17 11.9 2.9 2.9 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Pkinase PF00069.25 CBZ37662.1 - 2.5e-56 190.9 0.0 3.5e-56 190.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37662.1 - 1.1e-30 106.9 0.0 1.4e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ37662.1 - 0.0026 17.1 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Orthopox_A5L PF06193.11 CBZ37662.1 - 0.034 13.6 0.0 0.08 12.4 0.0 1.6 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like Pkinase_fungal PF17667.1 CBZ37662.1 - 0.11 11.3 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PLDc_2 PF13091.6 CBZ37664.1 - 7.1e-31 106.8 0.0 3.3e-23 82.0 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CBZ37664.1 - 3.6e-08 33.3 0.6 0.013 15.6 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DNA_repr_REX1B PF14966.6 CBZ37664.1 - 0.062 14.0 0.4 0.35 11.6 0.0 2.4 3 0 0 3 3 3 0 DNA repair REX1-B ubiquitin PF00240.23 CBZ37666.1 - 4e-16 58.5 0.0 4.5e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CBZ37666.1 - 4.5e-07 29.6 0.0 4.9e-07 29.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CBZ37666.1 - 0.00068 19.7 0.1 0.0015 18.6 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CBZ37666.1 - 0.0037 17.6 0.0 0.0039 17.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 CBZ37666.1 - 0.033 14.6 0.0 0.067 13.6 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-like domain DoxX PF07681.12 CBZ37667.1 - 0.0017 18.9 7.3 0.0017 18.9 7.3 1.6 2 1 0 2 2 2 1 DoxX PigN PF04987.14 CBZ37667.1 - 0.007 15.3 0.9 0.0078 15.1 0.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) HR_lesion PF05514.11 CBZ37667.1 - 0.036 14.3 5.7 0.11 12.6 5.7 1.7 1 1 0 1 1 1 0 HR-like lesion-inducing DUF4239 PF14023.6 CBZ37667.1 - 0.05 13.3 2.6 0.049 13.3 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) SIR2 PF02146.17 CBZ37668.1 - 3.7e-46 157.3 0.0 4.5e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family TraU PF06834.11 CBZ37668.1 - 0.022 14.1 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 TraU protein Zn-ribbon_8 PF09723.10 CBZ37668.1 - 0.068 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Zinc ribbon domain PNTB PF02233.16 CBZ37668.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.4 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit Pkinase PF00069.25 CBZ37669.1 - 7.6e-43 146.8 0.0 7.4e-42 143.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37669.1 - 7.4e-23 81.1 0.0 6.2e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CBZ37669.1 - 0.044 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CBZ37669.1 - 0.17 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like OGG_N PF07934.12 CBZ37671.1 - 4.8e-29 100.9 0.0 9.2e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CBZ37671.1 - 4.7e-09 36.7 0.0 8.3e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CBZ37671.1 - 0.00016 21.4 0.0 0.0017 18.2 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif Pro_dh-DNA_bdg PF14850.6 CBZ37672.1 - 0.25 11.9 1.0 15 6.2 0.2 3.3 3 0 0 3 3 3 0 DNA-binding domain of Proline dehydrogenase Pkinase PF00069.25 CBZ37673.1 - 3.7e-48 164.2 0.0 5.9e-23 81.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37673.1 - 1.8e-28 99.6 0.0 2.2e-15 56.6 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase DSPc PF00782.20 CBZ37673.1 - 1.6e-26 92.6 0.0 4.1e-26 91.4 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 CBZ37673.1 - 5.9e-09 35.6 10.2 7.6e-08 32.0 5.0 3.7 2 1 1 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 CBZ37673.1 - 1.1e-06 28.9 6.0 0.00042 20.6 0.2 4.0 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) Y_phosphatase PF00102.27 CBZ37673.1 - 0.00048 19.8 0.1 0.0013 18.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase ZYG-11_interact PF05884.12 CBZ37673.1 - 0.11 11.9 0.2 0.21 11.0 0.2 1.4 1 0 0 1 1 1 0 Interactor of ZYG-11 LRR_1 PF00560.33 CBZ37673.1 - 6.8 7.7 5.3 1.9e+02 3.3 0.1 4.6 4 0 0 4 4 4 0 Leucine Rich Repeat Thioredoxin PF00085.20 CBZ37674.1 - 1.3e-26 92.5 0.0 3.5e-26 91.2 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CBZ37674.1 - 1.4e-08 35.2 0.1 7.7e-07 29.5 0.1 3.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBZ37674.1 - 5.2e-06 26.7 0.0 0.00045 20.5 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_6 PF13848.6 CBZ37674.1 - 2.6e-05 24.2 0.0 0.003 17.5 0.0 2.6 3 0 0 3 3 3 1 Thioredoxin-like domain TraF PF13728.6 CBZ37674.1 - 0.00019 21.4 0.0 0.0012 18.8 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 CBZ37674.1 - 0.00048 19.6 0.0 0.00099 18.5 0.0 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CBZ37674.1 - 0.0007 19.5 0.0 0.0024 17.8 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CBZ37674.1 - 0.00082 19.1 0.1 0.0078 15.9 0.1 2.5 1 1 0 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 CBZ37674.1 - 0.013 15.6 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.6 CBZ37674.1 - 0.016 15.4 0.1 0.044 13.9 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_9 PF14595.6 CBZ37674.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin Exo_endo_phos PF03372.23 CBZ37676.1 - 1.1e-16 61.1 0.0 2e-15 56.9 0.0 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_65m PF03632.15 CBZ37678.1 - 5.7e-42 143.9 0.0 8.4e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 CBZ37678.1 - 7.7e-10 38.5 0.1 1.7e-09 37.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Kelch_1 PF01344.25 CBZ37679.1 - 1.1e-10 40.9 8.8 2.4e-05 23.8 0.1 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CBZ37679.1 - 4.6e-10 39.4 7.5 9.3e-05 22.4 0.0 5.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CBZ37679.1 - 9.2e-10 38.6 19.5 0.00021 21.5 0.0 7.4 8 1 0 8 8 8 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ37679.1 - 2e-09 37.2 11.2 0.00044 20.2 0.3 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 CBZ37679.1 - 2.2e-07 30.9 1.6 0.024 14.9 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CBZ37679.1 - 0.0017 18.3 5.2 6 7.0 0.0 5.4 5 0 0 5 5 5 1 Kelch motif TPD52 PF04201.15 CBZ37679.1 - 0.13 11.9 3.0 0.16 11.6 0.1 2.3 2 0 0 2 2 2 0 Tumour protein D52 family HA2 PF04408.23 CBZ37680.1 - 2.1e-16 60.1 0.0 5.5e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ37680.1 - 4.7e-12 46.2 0.0 3e-11 43.6 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CBZ37680.1 - 4.2e-09 36.6 0.0 1e-08 35.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 CBZ37680.1 - 7.9e-07 29.5 0.2 2.1e-06 28.1 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ37680.1 - 1.3e-06 28.7 0.1 4.3e-06 27.0 0.1 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CBZ37680.1 - 2.7e-06 27.3 1.4 3.9e-06 26.7 0.4 1.8 2 0 0 2 2 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CBZ37680.1 - 9e-05 22.3 0.0 0.0002 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CBZ37680.1 - 0.00016 21.4 0.1 0.0005 19.8 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 CBZ37680.1 - 0.0012 18.4 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 CBZ37680.1 - 0.0037 16.9 0.0 0.01 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CBZ37680.1 - 0.0054 15.8 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein cobW PF02492.19 CBZ37680.1 - 0.01 15.4 0.2 0.48 10.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CBZ37680.1 - 0.024 14.4 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CBZ37680.1 - 0.033 14.6 4.3 0.05 14.0 0.5 3.0 3 1 0 3 3 2 0 AAA ATPase domain ABC_tran PF00005.27 CBZ37680.1 - 0.033 14.7 0.0 0.12 12.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 CBZ37680.1 - 0.11 13.0 0.0 0.71 10.3 0.0 2.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 CBZ37680.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ATPase PF06745.13 CBZ37680.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.6 CBZ37680.1 - 0.17 11.6 0.2 0.67 9.7 0.1 2.0 1 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CBZ37680.1 - 0.22 12.0 0.0 0.39 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CBZ37680.1 - 0.53 10.2 2.2 1.5 8.8 0.1 2.8 3 1 0 3 3 2 0 NACHT domain Dynamin_N PF00350.23 CBZ37681.1 - 2e-14 54.0 0.0 7.6e-11 42.3 0.0 2.7 3 0 0 3 3 3 2 Dynamin family DUF5600 PF18150.1 CBZ37681.1 - 1.2e-10 41.9 0.0 2.9e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) MMR_HSR1 PF01926.23 CBZ37681.1 - 6.1e-07 29.5 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EHD_N PF16880.5 CBZ37681.1 - 0.00068 19.5 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein GET2 PF08690.10 CBZ37681.1 - 0.8 9.3 14.9 1.2 8.8 14.9 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4376 PF14301.6 CBZ37681.1 - 0.83 10.0 8.0 1.7 9.1 8.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) TFIIA PF03153.13 CBZ37681.1 - 2.5 8.0 19.7 3.2 7.6 19.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cofilin_ADF PF00241.20 CBZ37683.1 - 1.1e-16 60.7 0.0 3.2e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Cytochrom_B559 PF00283.19 CBZ37684.1 - 2.6 7.6 4.0 24 4.5 0.1 2.5 2 0 0 2 2 2 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits MMgT PF10270.9 CBZ37686.1 - 0.043 14.2 1.1 0.071 13.5 1.1 1.5 1 1 0 1 1 1 0 Membrane magnesium transporter TMEM144 PF07857.12 CBZ37686.1 - 0.13 11.2 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters Clat_adaptor_s PF01217.20 CBZ37687.1 - 4.9e-50 169.2 4.4 5.4e-50 169.0 4.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain tRNA-synt_2 PF00152.20 CBZ37688.1 - 2e-86 289.9 0.0 2.8e-86 289.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.15 CBZ37688.1 - 3.1e-33 115.1 0.1 5.5e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.25 CBZ37688.1 - 8.5e-11 41.7 0.0 1.9e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2046 PF09755.9 CBZ37690.1 - 1.5e-07 31.0 25.6 7.7e-07 28.6 21.8 2.5 2 1 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) ATG16 PF08614.11 CBZ37690.1 - 0.0017 18.6 9.3 0.0017 18.6 9.3 3.2 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 CBZ37690.1 - 0.0018 17.8 27.8 0.049 13.2 3.8 2.3 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain TMPIT PF07851.13 CBZ37690.1 - 0.0052 16.1 16.4 0.13 11.5 6.0 2.2 2 0 0 2 2 2 2 TMPIT-like protein Atg14 PF10186.9 CBZ37690.1 - 0.013 14.6 16.0 0.032 13.3 8.4 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 CBZ37690.1 - 0.022 14.3 18.1 0.15 11.6 10.2 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit TrmB PF01978.19 CBZ37690.1 - 0.095 12.6 1.5 0.2 11.6 0.6 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF4680 PF15730.5 CBZ37690.1 - 0.9 9.9 8.7 2.9 8.3 7.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4680) XhlA PF10779.9 CBZ37690.1 - 6.8 7.0 8.5 5.8 7.2 0.5 3.0 3 0 0 3 3 3 0 Haemolysin XhlA CBFD_NFYB_HMF PF00808.23 CBZ37691.1 - 1.9e-06 28.0 0.3 3.2e-06 27.3 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CBZ37691.1 - 0.00011 22.5 0.1 0.00018 21.8 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF1931 PF09123.11 CBZ37691.1 - 0.15 12.2 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) CENP-X PF09415.10 CBZ37691.1 - 0.2 12.0 0.4 0.4 11.0 0.4 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X EF-hand_7 PF13499.6 CBZ37693.1 - 1.7e-23 82.8 5.6 2.1e-15 56.9 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ37693.1 - 4.3e-21 72.8 9.9 1.8e-07 30.2 1.4 3.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CBZ37693.1 - 4.1e-19 66.8 3.5 3.5e-06 26.5 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CBZ37693.1 - 1.8e-14 53.3 8.5 1.9e-11 43.6 0.9 3.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CBZ37693.1 - 2.4e-13 50.2 0.3 1.4e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBZ37693.1 - 1.5e-12 46.4 4.9 0.00032 20.1 1.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 CBZ37693.1 - 1.1e-06 28.6 0.5 0.0048 16.8 0.2 2.2 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CBZ37693.1 - 0.00089 19.2 0.1 0.32 10.9 0.0 3.0 2 1 1 3 3 3 1 Caleosin related protein DUF3164 PF11363.8 CBZ37693.1 - 0.0058 16.3 0.2 0.072 12.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3164) EF-hand_14 PF17959.1 CBZ37693.1 - 0.0078 16.5 3.2 0.35 11.3 0.3 2.3 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 CBZ37693.1 - 0.013 15.5 5.6 0.1 12.6 1.2 2.5 1 1 2 3 3 3 0 Tellurite resistance protein TerB MgtE_N PF03448.17 CBZ37693.1 - 0.033 14.8 0.6 0.033 14.8 0.6 2.5 3 0 0 3 3 3 0 MgtE intracellular N domain SPARC_Ca_bdg PF10591.9 CBZ37693.1 - 0.068 13.5 1.7 1.2 9.5 0.4 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CBZ37693.1 - 0.082 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Dockerin type I domain SurA_N_2 PF13623.6 CBZ37693.1 - 0.086 12.7 4.6 0.96 9.3 0.4 2.4 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_11 PF08976.11 CBZ37693.1 - 0.11 13.3 0.4 0.43 11.5 0.1 1.9 2 0 0 2 2 2 0 EF-hand domain DUF3911 PF13050.6 CBZ37693.1 - 0.53 10.4 3.2 2.7 8.1 0.2 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3911) DUF1091 PF06477.13 CBZ37694.1 - 0.036 14.5 0.2 8.5 6.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1091) Aminotran_4 PF01063.19 CBZ37695.1 - 2e-34 119.4 0.0 2.6e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Glycos_transf_1 PF00534.20 CBZ37696.1 - 4.3e-28 98.0 0.0 7.5e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ37696.1 - 2.5e-15 57.1 0.1 2e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CBZ37696.1 - 1.4e-05 25.2 0.0 2.4e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CBZ37696.1 - 0.0031 17.9 0.0 0.011 16.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 DnaJ PF00226.31 CBZ37697.1 - 2.2e-19 69.3 0.1 5.8e-19 68.0 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 CBZ37697.1 - 5.6e-17 60.8 16.0 1.5e-05 24.6 0.1 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ37697.1 - 3.3e-14 51.8 26.2 0.00065 19.6 0.4 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ37697.1 - 2e-08 33.8 13.8 0.017 15.3 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ37697.1 - 2.5e-05 24.8 12.7 0.73 10.5 0.2 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ37697.1 - 3.1e-05 24.2 0.8 3.1e-05 24.2 0.8 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ37697.1 - 0.00027 21.1 0.1 7.6 7.2 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 CBZ37697.1 - 0.00086 19.4 0.6 0.07 13.2 0.0 3.0 2 1 1 3 3 3 1 Rapsyn N-terminal myristoylation and linker region TPR_11 PF13414.6 CBZ37697.1 - 0.003 17.2 2.3 1 9.1 0.3 4.0 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.6 CBZ37697.1 - 0.0082 16.6 8.8 13 6.3 0.1 5.6 4 2 2 6 6 5 0 Tetratricopeptide repeat Strep_SA_rep PF06696.11 CBZ37697.1 - 0.009 16.0 0.2 0.2 11.7 0.1 3.0 2 0 0 2 2 2 1 Streptococcal surface antigen repeat Syntaxin_2 PF14523.6 CBZ37697.1 - 0.12 12.7 0.0 23 5.4 0.0 2.5 2 0 0 2 2 2 0 Syntaxin-like protein TPR_7 PF13176.6 CBZ37697.1 - 0.16 12.0 12.1 3.5 7.9 0.1 5.5 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ37697.1 - 0.19 11.9 6.7 0.86 9.8 0.7 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ37697.1 - 0.45 10.8 13.8 0.35 11.1 0.4 4.5 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CBZ37697.1 - 0.64 10.8 13.8 2.8 8.8 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ37697.1 - 1.6 8.7 8.4 3.8 7.5 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat C1_1 PF00130.22 CBZ37698.1 - 0.033 14.1 0.6 0.083 12.8 0.6 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ADD_DNMT3 PF17980.1 CBZ37698.1 - 0.058 13.4 0.3 0.13 12.3 0.3 1.6 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 Sec7 PF01369.20 CBZ37699.1 - 2.2e-46 157.8 0.0 3.5e-46 157.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CBZ37699.1 - 1.4e-05 25.1 0.0 8.1e-05 22.6 0.0 2.3 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal GTP_EFTU PF00009.27 CBZ37700.1 - 2.9e-07 30.2 0.0 1.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CBZ37700.1 - 0.0049 16.8 0.1 0.79 9.6 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CBZ37700.1 - 0.01 15.6 2.1 0.4 10.4 0.3 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 CBZ37700.1 - 0.072 12.8 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CBZ37700.1 - 0.073 13.6 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter GTP_EFTU_D2 PF03144.25 CBZ37700.1 - 0.095 13.1 0.1 0.23 11.9 0.1 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Ribosomal_L35Ae PF01247.18 CBZ37701.1 - 2.7e-33 114.0 0.8 4.3e-33 113.3 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CBZ37701.1 - 4.9e-05 23.5 0.7 0.12 12.7 0.1 2.5 2 1 0 2 2 2 2 RimM N-terminal domain MFS_MOT1 PF16983.5 CBZ37703.1 - 0.034 14.6 3.5 0.067 13.6 3.5 1.6 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily DUF308 PF03729.13 CBZ37703.1 - 1.8 8.9 5.9 1.5 9.2 2.3 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) CENP-F_leu_zip PF10473.9 CBZ37705.1 - 0.00015 21.8 17.2 0.00015 21.8 17.2 8.3 3 2 5 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PriCT_1 PF08708.11 CBZ37705.1 - 0.17 11.6 2.0 2.5 7.9 0.1 3.4 3 0 0 3 3 3 0 Primase C terminal 1 (PriCT-1) M PF02370.16 CBZ37705.1 - 0.23 12.1 10.1 10 7.1 2.2 5.1 2 0 0 2 2 2 0 M protein repeat LRR_6 PF13516.6 CBZ37706.1 - 6.3e-06 25.8 4.8 0.083 13.0 0.1 4.3 5 0 0 5 5 5 3 Leucine Rich repeat BRX PF08381.11 CBZ37706.1 - 0.059 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 ANAPC4_WD40 PF12894.7 CBZ37707.1 - 0.00019 21.6 0.0 2.4 8.5 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Epiglycanin_C PF14654.6 CBZ37707.1 - 0.022 14.8 1.2 0.092 12.8 0.0 2.6 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region WD40 PF00400.32 CBZ37707.1 - 0.049 14.5 2.7 20 6.3 0.0 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat PP2C PF00481.21 CBZ37708.1 - 4.7e-52 177.2 0.0 6e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ37708.1 - 0.0002 21.1 0.1 0.00043 20.0 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CBZ37708.1 - 0.00094 19.1 0.2 0.22 11.4 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CBZ37709.1 - 1.2e-55 188.9 0.0 1.6e-55 188.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 CBZ37709.1 - 0.025 14.2 0.0 0.062 12.9 0.0 1.6 1 1 0 1 1 1 0 Protein phosphatase 2C Sec7 PF01369.20 CBZ37711.1 - 7.6e-49 165.9 0.0 3.7e-46 157.1 0.0 3.2 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 CBZ37711.1 - 7.9e-19 68.1 1.9 1.8e-18 67.0 0.4 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CBZ37711.1 - 6.1e-18 64.5 0.1 1.6e-17 63.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) APG6_N PF17675.1 CBZ37712.1 - 0.0097 16.4 0.8 0.0097 16.4 0.8 5.4 4 1 0 5 5 5 2 Apg6 coiled-coil region Cluap1 PF10234.9 CBZ37712.1 - 0.012 15.0 0.8 0.012 15.0 0.8 3.9 4 1 0 4 4 4 0 Clusterin-associated protein-1 Spc7 PF08317.11 CBZ37712.1 - 0.014 14.3 0.8 0.014 14.3 0.8 4.9 4 1 1 5 5 5 0 Spc7 kinetochore protein Replic_Relax PF13814.6 CBZ37712.1 - 0.038 14.1 4.5 0.1 12.6 4.1 1.9 1 1 0 1 1 1 0 Replication-relaxation Surfac_D-trimer PF09006.11 CBZ37712.1 - 0.072 13.0 0.0 8 6.4 0.0 2.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DASH_Dad3 PF08656.10 CBZ37712.1 - 2.4 8.3 13.3 0.041 14.0 1.6 3.5 3 1 0 3 3 3 0 DASH complex subunit Dad3 Jnk-SapK_ap_N PF09744.9 CBZ37712.1 - 2.7 8.2 50.9 0.15 12.3 1.8 5.2 5 0 0 5 5 5 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 CBZ37712.1 - 2.8 8.0 19.0 0.066 13.2 1.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 CBZ37712.1 - 9.6 6.5 14.4 4 7.8 0.4 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 CBZ37713.1 - 0.0097 16.4 0.8 0.0097 16.4 0.8 5.4 4 1 0 5 5 5 2 Apg6 coiled-coil region Cluap1 PF10234.9 CBZ37713.1 - 0.012 15.0 0.8 0.012 15.0 0.8 3.9 4 1 0 4 4 4 0 Clusterin-associated protein-1 Spc7 PF08317.11 CBZ37713.1 - 0.014 14.3 0.8 0.014 14.3 0.8 4.9 4 1 1 5 5 5 0 Spc7 kinetochore protein Replic_Relax PF13814.6 CBZ37713.1 - 0.038 14.1 4.5 0.1 12.6 4.1 1.9 1 1 0 1 1 1 0 Replication-relaxation Surfac_D-trimer PF09006.11 CBZ37713.1 - 0.072 13.0 0.0 8 6.4 0.0 2.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DASH_Dad3 PF08656.10 CBZ37713.1 - 2.4 8.3 13.3 0.041 14.0 1.6 3.5 3 1 0 3 3 3 0 DASH complex subunit Dad3 Jnk-SapK_ap_N PF09744.9 CBZ37713.1 - 2.8 8.2 50.9 0.15 12.3 1.8 5.2 5 0 0 5 5 5 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 CBZ37713.1 - 2.8 8.0 19.0 0.066 13.3 1.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 CBZ37713.1 - 9.6 6.5 14.4 3.9 7.8 0.4 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Shugoshin_N PF07558.11 CBZ37714.1 - 0.00035 20.4 26.5 1.1 9.2 0.1 8.4 8 1 1 9 9 9 3 Shugoshin N-terminal coiled-coil region C2 PF00168.30 CBZ37714.1 - 0.0017 18.6 0.0 0.0039 17.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain Peptidase_U32_C PF16325.5 CBZ37714.1 - 0.087 13.1 0.5 34 4.8 0.0 3.8 3 1 0 3 3 3 0 Peptidase family U32 C-terminal domain Fez1 PF06818.15 CBZ37714.1 - 0.24 11.8 72.9 0.15 12.5 20.5 5.3 2 1 2 4 4 4 0 Fez1 DUF1040 PF06288.13 CBZ37714.1 - 0.25 11.8 4.8 0.3 11.5 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1040) DUF3573 PF12097.8 CBZ37714.1 - 0.94 8.2 6.2 0.56 9.0 0.2 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3573) ACP_PD PF04336.12 CBZ37714.1 - 0.94 9.9 10.7 1.2 9.6 0.6 4.3 4 0 0 4 4 4 0 Acyl carrier protein phosphodiesterase DUF3138 PF11336.8 CBZ37714.1 - 0.97 8.0 6.7 0.057 12.0 0.8 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) IFT57 PF10498.9 CBZ37715.1 - 3e-05 23.2 0.7 3e-05 23.2 0.7 1.8 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 Spc42p PF11544.8 CBZ37715.1 - 1.3 9.0 4.8 0.34 10.9 0.2 2.4 3 0 0 3 3 3 0 Spindle pole body component Spc42p OmpH PF03938.14 CBZ37715.1 - 3.8 7.8 16.0 0.78 10.1 3.2 3.0 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 CBZ37715.1 - 8 6.9 6.4 1.9 9.0 0.1 3.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) RecG_N PF17190.4 CBZ37715.1 - 8.3 7.2 8.4 5.2 7.9 0.5 3.0 3 0 0 3 3 3 0 RecG N-terminal helical domain Golgin_A5 PF09787.9 CBZ37715.1 - 8.8 5.7 20.0 0.93 8.9 1.8 3.1 2 1 0 3 3 3 0 Golgin subfamily A member 5 DUF641 PF04859.12 CBZ37716.1 - 0.0046 17.3 19.5 0.0081 16.5 0.2 4.0 4 0 0 4 4 4 2 Plant protein of unknown function (DUF641) DUF4515 PF14988.6 CBZ37716.1 - 0.11 12.3 25.0 0.12 12.2 2.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4515) FliD_C PF07195.12 CBZ37716.1 - 1.3 8.3 5.7 7.8 5.8 0.2 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus FH2 PF02181.23 CBZ37716.1 - 1.6 7.8 16.8 1.5 7.9 1.0 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain Glutaredoxin2_C PF04399.13 CBZ37716.1 - 1.7 8.5 10.1 12 5.7 0.3 3.8 4 0 0 4 4 4 0 Glutaredoxin 2, C terminal domain Spc7 PF08317.11 CBZ37716.1 - 9.7 5.0 39.9 3.2 6.6 4.8 4.0 3 1 0 3 3 3 0 Spc7 kinetochore protein Corona_S2 PF01601.16 CBZ37717.1 - 0.037 12.5 0.1 0.067 11.7 0.1 1.4 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Ribosomal_L14 PF00238.19 CBZ37717.1 - 0.53 10.4 2.8 1.7 8.7 1.1 2.3 1 1 0 2 2 2 0 Ribosomal protein L14p/L23e HetR_C PF18460.1 CBZ37717.1 - 3.7 7.5 12.7 0.41 10.6 0.8 4.2 4 1 1 5 5 5 0 Heterocyst differentiation regulator C-terminal Hood domain Alba PF01918.21 CBZ37718.1 - 5e-17 61.5 0.3 7.2e-17 61.0 0.3 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 CBZ37718.1 - 0.0033 17.4 0.1 0.0051 16.8 0.1 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Caprin-1_C PF12287.8 CBZ37718.1 - 7.6 6.6 5.7 9.8 6.2 5.7 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Adap_comp_sub PF00928.21 CBZ37719.1 - 3.2e-58 197.2 0.0 3.9e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBZ37719.1 - 0.00025 21.0 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ACBP PF00887.19 CBZ37720.1 - 8.4e-16 58.0 0.5 9.3e-16 57.8 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein TIP49 PF06068.13 CBZ37721.1 - 1.2e-157 524.6 0.8 1.2e-157 524.6 0.8 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 CBZ37721.1 - 6.3e-25 87.1 0.7 2e-24 85.5 0.7 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CBZ37721.1 - 2e-08 34.8 2.0 1.2e-05 25.7 0.1 3.1 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBZ37721.1 - 2.4e-07 30.6 0.6 0.0002 21.1 0.1 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CBZ37721.1 - 6.8e-06 26.1 0.2 0.0016 18.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 CBZ37721.1 - 9.3e-06 25.2 0.2 1.9e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CBZ37721.1 - 1.7e-05 25.3 0.1 8.4e-05 23.0 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CBZ37721.1 - 3e-05 23.5 1.3 0.00061 19.2 0.7 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CBZ37721.1 - 3.7e-05 24.0 0.8 0.14 12.4 0.0 2.9 2 1 1 3 3 2 2 AAA domain AAA_19 PF13245.6 CBZ37721.1 - 0.00014 22.2 5.9 0.00063 20.1 1.6 3.0 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CBZ37721.1 - 0.0037 17.0 0.0 1.6 8.4 0.1 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.6 CBZ37721.1 - 0.0038 17.6 0.1 0.037 14.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CBZ37721.1 - 0.004 16.5 0.4 0.01 15.1 0.4 1.6 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.12 CBZ37721.1 - 0.0053 16.6 0.3 0.022 14.6 0.1 2.3 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein NACHT PF05729.12 CBZ37721.1 - 0.0092 15.9 0.1 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 CBZ37721.1 - 0.013 15.8 0.1 0.03 14.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CBZ37721.1 - 0.019 14.3 1.8 0.02 14.2 0.2 1.9 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.6 CBZ37721.1 - 0.024 15.1 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CBZ37721.1 - 0.025 14.3 0.2 0.075 12.8 0.2 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CBZ37721.1 - 0.027 14.0 0.2 0.089 12.3 0.2 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CBZ37721.1 - 0.029 14.1 0.2 0.44 10.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBZ37721.1 - 0.03 14.1 0.1 0.17 11.6 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2075 PF09848.9 CBZ37721.1 - 0.035 13.4 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GATase PF00117.28 CBZ37721.1 - 0.047 13.5 0.1 0.95 9.2 0.0 2.2 2 0 0 2 2 2 0 Glutamine amidotransferase class-I TFIID-31kDa PF02291.15 CBZ37721.1 - 0.057 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TsaE PF02367.17 CBZ37721.1 - 0.064 13.3 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Parvo_NS1 PF01057.17 CBZ37721.1 - 0.066 12.3 0.2 0.13 11.3 0.2 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 CBZ37721.1 - 0.076 13.1 0.0 0.89 9.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CBZ37721.1 - 0.085 12.4 0.6 0.38 10.3 0.1 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_33 PF13671.6 CBZ37721.1 - 0.094 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBZ37721.1 - 0.094 13.2 0.2 0.21 12.1 0.2 1.6 1 0 0 1 1 1 0 ABC transporter Suv3_C_1 PF18147.1 CBZ37722.1 - 5.9e-09 35.7 0.2 2.6e-08 33.6 0.2 2.2 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 SUV3_C PF12513.8 CBZ37722.1 - 1.6e-08 34.4 0.3 3.2e-08 33.4 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CBZ37722.1 - 4.2e-05 23.8 0.0 0.00031 21.1 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ37722.1 - 0.013 15.3 0.0 0.076 12.8 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase SCAB-ABD PF16711.5 CBZ37722.1 - 0.043 13.7 0.3 0.15 11.9 0.3 1.9 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein Kinesin PF00225.23 CBZ37722.1 - 0.077 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain DUF936 PF06075.12 CBZ37722.1 - 0.1 11.5 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) PhoLip_ATPase_C PF16212.5 CBZ37723.1 - 2.6e-43 148.6 22.5 2.6e-43 148.6 22.5 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBZ37723.1 - 2.1e-22 78.5 0.8 5.5e-22 77.2 0.8 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CBZ37723.1 - 2.3e-12 47.7 2.3 1.1e-06 29.1 1.9 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ37723.1 - 5e-09 36.1 0.0 1.7e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CBZ37723.1 - 7.6e-05 22.3 0.3 0.0025 17.4 0.1 2.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CBZ37723.1 - 0.0017 18.1 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ37723.1 - 0.017 15.5 0.1 8.3 6.8 0.0 2.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Castor_Poll_mid PF06241.12 CBZ37723.1 - 0.043 13.8 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel Hydrolase_6 PF13344.6 CBZ37723.1 - 0.18 11.9 0.0 0.68 10.1 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TPR_4 PF07721.14 CBZ37724.1 - 0.39 11.5 4.2 6.1 7.8 0.0 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF21 PF01595.20 CBZ37725.1 - 6.5e-34 117.1 1.7 1.8e-33 115.7 0.3 2.0 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CBZ37725.1 - 5.7e-06 26.7 0.1 0.017 15.6 0.1 2.6 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 CBZ37725.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DIM PF08194.12 CBZ37725.1 - 5.1 7.4 5.6 23 5.3 5.6 2.2 1 0 0 1 1 1 0 DIM protein Vps52 PF04129.12 CBZ37726.1 - 5.2e-15 55.2 1.4 4.9e-14 52.0 0.5 2.1 2 0 0 2 2 2 1 Vps52 / Sac2 family Sec3_C PF09763.9 CBZ37726.1 - 0.0001 20.9 0.1 0.21 9.9 0.0 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec3 TMCO5 PF14992.6 CBZ37726.1 - 0.048 13.2 0.3 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 TMCO5 family ATG16 PF08614.11 CBZ37726.1 - 4.8 7.4 6.8 1.2 9.4 0.2 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FAD_binding_1 PF00667.20 CBZ37727.1 - 6.5e-29 101.1 0.0 9.2e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CBZ37727.1 - 4.1e-24 85.4 0.0 8.7e-24 84.4 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CBZ37727.1 - 3.6e-16 59.8 0.0 6.3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain WD40 PF00400.32 CBZ37728.1 - 5.7e-14 52.3 3.4 0.0017 19.1 0.2 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37728.1 - 2.8e-06 27.5 0.2 0.0039 17.5 0.1 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain R_equi_Vir PF05526.11 CBZ37728.1 - 0.43 10.4 5.5 5.6 6.8 0.0 3.6 4 1 0 4 4 4 0 Rhodococcus equi virulence-associated protein RRM_1 PF00076.22 CBZ37730.1 - 1.2e-11 44.3 0.0 2.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 CBZ37730.1 - 0.0014 19.0 0.5 0.0049 17.3 0.0 1.9 1 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G MFS_1 PF07690.16 CBZ37732.1 - 7.6e-22 77.7 22.4 1.5e-11 43.9 7.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily WBS_methylT PF12589.8 CBZ37735.1 - 2.8e-10 40.8 9.3 6.9e-10 39.6 9.3 1.7 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 CBZ37735.1 - 6.2e-09 36.4 0.0 0.0016 19.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ37735.1 - 2.2e-07 31.5 0.0 0.00034 21.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ37735.1 - 0.00021 22.0 0.0 0.016 15.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ37735.1 - 0.00051 19.9 0.0 0.0054 16.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ37735.1 - 0.0026 17.6 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CDC45 PF02724.14 CBZ37735.1 - 1.1 7.5 12.2 0.1 10.9 4.7 2.0 2 0 0 2 2 2 0 CDC45-like protein FAM176 PF14851.6 CBZ37736.1 - 0.12 12.0 6.5 0.19 11.4 0.1 2.3 2 0 0 2 2 2 0 FAM176 family FYDLN_acid PF09538.10 CBZ37736.1 - 2.7 8.7 11.8 5.8 7.6 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Metallophos PF00149.28 CBZ37738.1 - 3.3e-15 57.1 0.0 5.3e-10 40.1 0.4 3.4 2 2 0 2 2 2 2 Calcineurin-like phosphoesterase Ribosomal_S19e PF01090.19 CBZ37739.1 - 1.1e-42 145.0 0.0 1.3e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e Mrr_N PF14338.6 CBZ37739.1 - 0.01 15.9 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 Mrr N-terminal domain SRP68 PF16969.5 CBZ37740.1 - 8.6e-53 180.2 13.8 3.3e-48 165.0 13.8 3.0 1 1 0 1 1 1 1 RNA-binding signal recognition particle 68 Terpene_synth_C PF03936.16 CBZ37740.1 - 0.023 14.1 0.2 0.1 11.9 0.0 2.0 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain SRP54 PF00448.22 CBZ37740.1 - 0.043 13.5 0.1 0.36 10.4 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TPR_2 PF07719.17 CBZ37740.1 - 0.076 13.2 0.5 0.076 13.2 0.5 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ37740.1 - 0.12 12.6 3.1 0.2 12.0 0.6 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 CBZ37741.1 - 8.4e-08 32.8 0.4 2.5e-07 31.2 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ37741.1 - 7.4e-06 26.3 0.2 8.8e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CBZ37741.1 - 0.0018 18.3 0.0 0.0069 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CBZ37741.1 - 0.029 13.4 0.1 0.053 12.6 0.1 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 CBZ37741.1 - 0.043 13.5 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CBZ37741.1 - 0.056 13.4 0.0 0.097 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2760 PF10816.8 CBZ37741.1 - 0.086 12.7 0.1 15 5.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2760) AAA_18 PF13238.6 CBZ37741.1 - 0.13 12.8 0.0 0.41 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CBZ37741.1 - 0.14 12.3 2.5 0.24 11.6 0.0 2.6 3 1 0 3 3 3 0 AAA domain VWA_2 PF13519.6 CBZ37741.1 - 0.15 12.7 0.3 27 5.5 0.0 2.6 2 0 0 2 2 2 0 von Willebrand factor type A domain Peptidase_M14 PF00246.24 CBZ37744.1 - 1.1e-16 61.5 0.0 5.1e-16 59.3 0.0 2.0 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 CBZ37744.1 - 3.3e-07 30.6 0.1 7e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain AstE_AspA PF04952.14 CBZ37744.1 - 8.5e-05 21.8 0.1 0.00014 21.0 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family PIN_11 PF18479.1 CBZ37744.1 - 0.029 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 PIN like domain cNMP_binding PF00027.29 CBZ37745.1 - 3.3e-25 88.0 0.2 1.5e-12 47.4 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CBZ37745.1 - 0.0036 17.0 0.2 0.013 15.2 0.1 1.9 2 0 0 2 2 2 1 Cupin domain Urm1 PF09138.11 CBZ37746.1 - 4e-24 84.8 0.0 4.6e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CBZ37746.1 - 5.3e-08 33.4 0.3 6.6e-08 33.1 0.3 1.1 1 0 0 1 1 1 1 ThiS family TGS PF02824.21 CBZ37746.1 - 0.015 15.3 0.3 0.039 14.0 0.2 1.7 2 0 0 2 2 2 0 TGS domain GTP_EFTU PF00009.27 CBZ37747.1 - 7.3e-28 97.4 0.1 1.1e-27 96.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CBZ37747.1 - 8.2e-08 32.5 0.2 2.4e-07 31.0 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ37747.1 - 8.2e-07 29.1 0.1 2.2e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBZ37747.1 - 0.00051 19.5 0.6 0.0068 15.9 0.2 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CBZ37747.1 - 0.0052 16.5 0.1 2.8 7.7 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CBZ37747.1 - 0.0066 16.0 2.0 0.014 14.9 0.5 2.2 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU_D4 PF14578.6 CBZ37747.1 - 0.045 13.7 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 ATP_bind_1 PF03029.17 CBZ37747.1 - 0.085 12.6 0.0 1.8 8.3 0.0 2.7 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Hexapep PF00132.24 CBZ37748.1 - 3.9e-10 39.0 12.4 1.7e-06 27.5 0.9 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CBZ37748.1 - 0.0024 17.6 13.8 0.92 9.3 0.2 3.6 2 2 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase SAS4 PF15460.6 CBZ37749.1 - 0.023 14.8 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 Ribosomal_L33 PF00471.20 CBZ37749.1 - 0.082 13.4 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L33 Ribosomal_L3 PF00297.22 CBZ37750.1 - 1.6e-41 142.5 0.3 1.8e-41 142.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Patatin PF01734.22 CBZ37751.1 - 6e-09 36.4 1.4 0.00062 20.0 0.7 2.4 1 1 0 2 2 2 2 Patatin-like phospholipase Thioredoxin PF00085.20 CBZ37753.1 - 0.073 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin EF-hand_6 PF13405.6 CBZ37755.1 - 1.7e-14 52.4 0.0 0.0005 19.8 0.0 6.9 7 0 0 7 7 7 4 EF-hand domain EF-hand_7 PF13499.6 CBZ37755.1 - 1.7e-14 54.0 0.0 0.00019 21.8 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_8 PF13833.6 CBZ37755.1 - 1.1e-12 47.6 0.2 5.2e-09 35.8 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ37755.1 - 1.3e-12 46.3 0.1 0.00022 20.5 0.0 5.8 6 0 0 6 6 6 3 EF hand EF-hand_5 PF13202.6 CBZ37755.1 - 1.3e-11 43.4 1.2 0.06 12.9 0.0 6.0 7 0 0 7 7 7 3 EF hand Spc7 PF08317.11 CBZ37757.1 - 0.00012 21.1 14.8 0.00017 20.6 14.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 CBZ37757.1 - 0.19 11.3 5.1 0.2 11.2 5.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 CBZ37757.1 - 0.28 9.0 2.2 0.29 9.0 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 CBZ37757.1 - 1.8 8.4 20.3 0.42 10.4 7.1 2.7 1 1 2 3 3 3 0 Septum formation initiator ADIP PF11559.8 CBZ37757.1 - 2 8.5 18.9 3.1 7.9 18.9 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Nup88 PF10168.9 CBZ37757.1 - 7.1 4.3 13.0 9.2 3.9 13.0 1.0 1 0 0 1 1 1 0 Nuclear pore component NDK PF00334.19 CBZ37758.1 - 4.7e-15 55.8 0.0 3.6e-14 52.9 0.0 2.2 2 1 0 2 2 2 1 Nucleoside diphosphate kinase DUF1126 PF06565.12 CBZ37758.1 - 0.023 14.5 0.0 0.14 12.0 0.0 2.1 1 1 0 1 1 1 0 DUF1126 PH-like domain Inhibitor_I10 PF12559.8 CBZ37758.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Serine endopeptidase inhibitors DUF3682 PF12446.8 CBZ37759.1 - 0.029 14.8 5.3 0.055 14.0 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) LRR_6 PF13516.6 CBZ37759.1 - 0.033 14.2 0.9 0.34 11.1 0.0 2.5 2 0 0 2 2 2 0 Leucine Rich repeat CENP-B_dimeris PF09026.10 CBZ37759.1 - 0.039 14.3 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Rhodanese PF00581.20 CBZ37761.1 - 1.6e-11 44.7 0.1 2.8e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.25 CBZ37762.1 - 2.6e-20 72.9 0.0 7.8e-20 71.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 CBZ37762.1 - 0.006 16.5 0.2 0.48 10.3 0.0 3.1 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ37762.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CBZ37762.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RMP PF14996.6 CBZ37763.1 - 1.2e-10 41.9 7.8 1.6e-09 38.2 4.5 3.1 2 1 0 2 2 2 1 Retinal Maintenance Adeno_E1B_55K PF01696.17 CBZ37764.1 - 0.00092 18.0 0.6 0.00092 18.0 0.6 2.1 2 0 0 2 2 2 1 Adenovirus EB1 55K protein / large t-antigen Beta_helix PF13229.6 CBZ37764.1 - 0.0016 18.3 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 2 Right handed beta helix region EcKinase PF02958.20 CBZ37764.1 - 0.033 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Cyt-b5 PF00173.28 CBZ37765.1 - 1.1e-06 28.6 0.1 2.1e-06 27.8 0.1 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mito_carr PF00153.27 CBZ37766.1 - 1.8e-47 159.2 4.5 2.7e-23 81.7 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein SWIM PF04434.17 CBZ37767.1 - 1.6 8.4 5.1 1.1 8.9 1.0 2.4 2 0 0 2 2 2 0 SWIM zinc finger Phostensin_N PF13916.6 CBZ37768.1 - 0.022 15.1 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal zf-CCHC PF00098.23 CBZ37769.1 - 0.0049 16.9 3.3 0.0049 16.9 3.3 3.7 4 0 0 4 4 4 1 Zinc knuckle WW PF00397.26 CBZ37769.1 - 0.015 15.4 3.8 0.015 15.4 3.8 2.2 2 0 0 2 2 2 0 WW domain zinc-ribbons_6 PF07191.12 CBZ37769.1 - 1 9.4 18.0 1.5 8.9 10.9 3.0 2 1 0 2 2 2 0 zinc-ribbons Herpes_capsid PF06112.11 CBZ37769.1 - 2.5 8.2 14.9 4.2 7.4 14.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DZR PF12773.7 CBZ37769.1 - 7 6.8 18.5 5.6 7.1 0.5 3.1 2 1 0 2 2 2 0 Double zinc ribbon eIF3g PF12353.8 CBZ37769.1 - 7.2 7.0 22.5 7.2 7.0 6.8 3.7 1 1 2 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Gemini_mov PF01708.16 CBZ37770.1 - 2.1 8.1 3.9 4.5 7.1 3.9 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein CesT PF05932.13 CBZ37772.1 - 3.8e-13 49.6 0.2 1e-12 48.2 0.2 1.8 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family ubiquitin PF00240.23 CBZ37772.1 - 0.011 15.5 0.1 0.065 13.0 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin family Rad60-SLD PF11976.8 CBZ37772.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like LRS4 PF10422.9 CBZ37772.1 - 0.033 13.8 1.3 0.05 13.2 1.3 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 ApoLp-III PF07464.11 CBZ37772.1 - 0.14 12.3 0.6 0.25 11.4 0.6 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PRKG1_interact PF15898.5 CBZ37772.1 - 0.94 10.4 13.5 0.51 11.3 7.0 2.4 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain BST2 PF16716.5 CBZ37772.1 - 1 10.0 5.8 7.2 7.3 5.1 2.5 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 DUF641 PF04859.12 CBZ37772.1 - 6.9 7.0 9.9 0.99 9.7 4.6 2.2 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Epimerase PF01370.21 CBZ37774.1 - 6.8e-15 55.2 0.0 1.1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CBZ37774.1 - 1.1e-08 35.2 0.0 2.4e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CBZ37774.1 - 2.3e-07 30.6 0.1 2.5e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family 3Beta_HSD PF01073.19 CBZ37774.1 - 2.3e-06 26.8 0.1 8.6e-06 25.0 0.1 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CBZ37774.1 - 6.5e-06 25.8 0.0 1.9e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 CBZ37774.1 - 0.082 12.3 0.1 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase GCV_H PF01597.19 CBZ37776.1 - 0.001 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein DUF1344 PF07076.11 CBZ37776.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) DUF4520 PF15016.6 CBZ37776.1 - 0.083 13.0 0.2 0.23 11.6 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4520) PhoLip_ATPase_C PF16212.5 CBZ37777.1 - 2.8e-36 125.6 23.6 2.8e-36 125.6 23.6 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CBZ37777.1 - 2.8e-13 49.4 4.7 8e-13 47.9 4.7 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CBZ37777.1 - 6.9e-13 48.5 0.8 3.4e-12 46.3 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CBZ37777.1 - 9.5e-09 35.2 0.0 9.8e-08 32.0 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CBZ37777.1 - 9.9e-09 35.8 3.3 0.0026 18.1 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CBZ37777.1 - 0.0018 18.0 0.2 0.0031 17.3 0.2 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L2 PF00181.23 CBZ37777.1 - 0.089 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal Proteins L2, RNA binding domain TPP_enzyme_N PF02776.18 CBZ37780.1 - 1.1e-33 116.2 0.1 2.1e-33 115.3 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CBZ37780.1 - 1.7e-20 73.3 0.0 4.4e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CBZ37780.1 - 2.7e-15 56.3 0.0 5.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Chitin_synth_1 PF01644.17 CBZ37780.1 - 0.094 12.7 0.1 3.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Chitin synthase DXP_synthase_N PF13292.6 CBZ37780.1 - 0.14 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DRMBL PF07522.14 CBZ37781.1 - 2.6e-17 63.0 0.0 4.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 CBZ37781.1 - 0.52 10.3 5.0 13 5.7 4.8 2.3 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF4379 PF14311.6 CBZ37782.1 - 8.7e-16 58.0 0.3 1.5e-15 57.3 0.3 1.4 1 0 0 1 1 1 1 Probable Zinc-ribbon domain HypA PF01155.19 CBZ37782.1 - 0.1 12.6 0.8 0.13 12.3 0.5 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin_2 PF18073.1 CBZ37782.1 - 0.73 9.6 5.5 4.5 7.1 0.4 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-UBP PF02148.19 CBZ37783.1 - 1e-15 57.8 8.1 1e-15 57.8 8.1 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UPF0242 PF06785.11 CBZ37783.1 - 0.036 14.2 1.8 0.074 13.1 1.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LuxC PF05893.14 CBZ37783.1 - 0.044 12.8 0.1 0.071 12.1 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) RasGAP_C PF03836.15 CBZ37783.1 - 0.12 12.5 0.9 0.31 11.2 0.9 1.6 1 0 0 1 1 1 0 RasGAP C-terminus DAGK_cat PF00781.24 CBZ37783.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Spc7 PF08317.11 CBZ37783.1 - 2.1 7.1 7.0 2.2 7.1 5.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein UPF0054 PF02130.17 CBZ37785.1 - 1.7e-22 79.6 0.0 2.3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 LRR_6 PF13516.6 CBZ37786.1 - 1.8e-05 24.4 8.1 0.03 14.4 1.4 4.5 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 CBZ37786.1 - 0.15 12.6 6.9 1.7 9.2 0.8 3.4 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ37786.1 - 0.17 12.5 5.2 35 5.5 0.2 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat OrfB_IS605 PF01385.19 CBZ37787.1 - 0.16 12.2 1.8 0.25 11.6 1.8 1.4 1 1 0 1 1 1 0 Probable transposase p450 PF00067.22 CBZ37788.1 - 5.9e-59 200.0 0.0 8.4e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1477 PF07346.11 CBZ37788.1 - 0.0031 17.7 0.2 0.0063 16.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1477) AAA PF00004.29 CBZ37790.1 - 1.6e-34 119.2 0.0 4.7e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ37790.1 - 2.3e-05 24.4 0.0 0.00012 22.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ37790.1 - 0.00038 20.7 0.8 0.092 13.0 0.1 3.0 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 CBZ37790.1 - 0.00041 20.1 0.0 0.002 17.9 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ37790.1 - 0.00058 20.3 0.3 0.00058 20.3 0.3 3.0 2 2 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CBZ37790.1 - 0.0027 17.6 0.3 2.2 8.2 0.0 2.9 2 1 1 3 3 3 2 NACHT domain AAA_33 PF13671.6 CBZ37790.1 - 0.0067 16.6 0.0 0.027 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBZ37790.1 - 0.0088 15.8 0.6 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.6 CBZ37790.1 - 0.018 15.5 0.0 0.049 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 CBZ37790.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Vps4_C PF09336.10 CBZ37790.1 - 0.032 14.2 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 CBZ37790.1 - 0.039 13.2 0.0 0.096 11.9 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CBZ37790.1 - 0.057 12.8 0.1 0.21 10.9 0.1 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CBZ37790.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 CBZ37790.1 - 0.13 12.3 0.0 0.33 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Hydin_ADK PF17213.3 CBZ37790.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.4 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain RNA_helicase PF00910.22 CBZ37790.1 - 0.14 12.5 0.0 0.98 9.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase Tyr_Deacylase PF02580.16 CBZ37791.1 - 3.5e-27 95.7 0.0 5e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase POLO_box PF00659.18 CBZ37792.1 - 0.18 12.0 0.2 0.63 10.3 0.2 1.9 1 1 0 1 1 1 0 POLO box duplicated region Aldose_epim PF01263.20 CBZ37793.1 - 8.9e-32 110.6 0.0 1.2e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase HECT PF00632.25 CBZ37794.1 - 2e-10 40.7 0.0 0.0034 16.9 0.0 3.1 3 0 0 3 3 3 3 HECT-domain (ubiquitin-transferase) HECT PF00632.25 CBZ37795.1 - 5.1e-08 32.8 0.0 5.3e-07 29.4 0.2 2.0 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Lactamase_B PF00753.27 CBZ37797.1 - 1.8e-07 31.4 0.3 5.6e-07 29.8 0.3 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CBZ37797.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta-Casp PF10996.8 CBZ37798.1 - 7.6e-32 109.9 0.0 2.8e-31 108.0 0.0 2.1 1 0 0 1 1 1 1 Beta-Casp domain CPSF73-100_C PF11718.8 CBZ37798.1 - 1.3e-28 100.1 0.0 1.9e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lactamase_B PF00753.27 CBZ37798.1 - 8.2e-24 84.7 0.0 1.4e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CBZ37798.1 - 1.5e-16 60.4 0.0 3.8e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CBZ37798.1 - 6e-13 48.5 0.0 1.9e-12 46.9 0.0 1.9 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CBZ37798.1 - 5.4e-10 39.1 0.1 3.1e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CBZ37798.1 - 0.00078 19.4 0.0 0.0028 17.5 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Topoisom_I PF01028.20 CBZ37799.1 - 2.8e-92 308.2 1.1 5.7e-92 307.2 1.1 1.5 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CBZ37799.1 - 8e-92 306.6 1.4 8e-92 306.6 1.4 3.1 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment DUF3891 PF13030.6 CBZ37799.1 - 0.03 14.1 2.5 0.46 10.2 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3891) Peptidase_A3 PF02160.15 CBZ37799.1 - 0.37 10.2 4.2 0.83 9.1 4.2 1.5 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) TA_inhibitor PF17574.2 CBZ37799.1 - 0.84 9.7 4.6 15 5.7 0.5 2.7 2 0 0 2 2 2 0 Inhibitor of toxin/antitoxin system (Gp4.5) LRR_9 PF14580.6 CBZ37800.1 - 1.6e-06 27.7 0.1 3.2e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBZ37800.1 - 0.01 16.2 3.0 0.02 15.3 0.0 2.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) bZIP_1 PF00170.21 CBZ37800.1 - 0.3 11.2 4.2 0.22 11.6 0.4 2.7 3 0 0 3 3 3 0 bZIP transcription factor zf-RanBP PF00641.18 CBZ37801.1 - 2.5e-05 23.5 2.6 2.5e-05 23.5 2.6 1.7 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-CCCH_4 PF18044.1 CBZ37801.1 - 0.00049 19.8 0.8 0.00049 19.8 0.8 3.0 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ37801.1 - 0.0013 18.7 0.9 0.0038 17.2 0.9 1.9 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CBZ37801.1 - 0.046 13.6 1.6 0.13 12.2 1.6 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Amidinotransf PF02274.17 CBZ37802.1 - 5.1e-10 39.0 0.0 7.1e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Amidinotransferase LRR_6 PF13516.6 CBZ37803.1 - 0.13 12.4 0.4 0.61 10.3 0.0 2.3 2 0 0 2 2 2 0 Leucine Rich repeat TPR_12 PF13424.6 CBZ37804.1 - 5.1e-32 110.0 23.2 3.2e-08 33.8 2.9 6.6 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ37804.1 - 7.1e-27 92.5 26.6 1.9e-08 33.9 0.0 7.5 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ37804.1 - 5.4e-07 29.3 28.9 0.02 15.1 0.2 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat Drf_FH3 PF06367.16 CBZ37804.1 - 0.0026 17.4 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 Diaphanous FH3 Domain TPR_7 PF13176.6 CBZ37804.1 - 0.0065 16.4 15.3 0.13 12.4 0.1 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ37804.1 - 0.055 13.9 6.8 14 6.4 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2225 PF09986.9 CBZ37804.1 - 0.056 13.2 2.5 10 5.8 0.1 3.2 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) GPW_gp25 PF04965.14 CBZ37804.1 - 0.058 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Gene 25-like lysozyme DUF3301 PF11743.8 CBZ37804.1 - 0.073 12.8 3.1 2.3 7.9 0.0 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF3301) TPR_1 PF00515.28 CBZ37804.1 - 0.12 12.3 17.4 15 5.6 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ37804.1 - 0.25 12.0 21.1 7.8 7.2 0.2 6.6 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ37804.1 - 0.39 11.7 23.0 6.1 7.9 0.1 7.2 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ37804.1 - 1.2 9.5 28.5 0.22 11.7 0.4 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ37804.1 - 7.6 7.1 13.4 0.63 10.6 0.9 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TIP49 PF06068.13 CBZ37805.1 - 1.8e-166 553.6 0.7 2.3e-166 553.3 0.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CBZ37805.1 - 6.2e-20 71.1 0.8 2e-19 69.5 0.2 2.3 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 CBZ37805.1 - 7e-12 45.9 0.8 3.7e-07 30.6 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBZ37805.1 - 1.7e-11 44.1 0.1 8.9e-08 32.0 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBZ37805.1 - 6.7e-07 29.7 0.1 0.0098 16.2 0.0 2.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ37805.1 - 2.8e-05 24.6 0.1 0.00035 21.0 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 CBZ37805.1 - 0.00013 21.4 0.2 0.0084 15.5 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBZ37805.1 - 0.00034 20.6 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CBZ37805.1 - 0.0028 18.0 0.6 2.5 8.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CBZ37805.1 - 0.0061 16.7 0.0 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 CBZ37805.1 - 0.0085 15.5 0.0 0.03 13.7 0.0 1.8 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_28 PF13521.6 CBZ37805.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 CBZ37805.1 - 0.015 14.1 0.8 1.6 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 CBZ37805.1 - 0.016 14.8 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CBZ37805.1 - 0.017 14.9 0.0 0.066 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CBZ37805.1 - 0.022 14.8 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CBZ37805.1 - 0.051 13.1 0.1 0.29 10.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 CBZ37805.1 - 0.052 14.1 0.1 0.18 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CBZ37805.1 - 0.059 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 CBZ37805.1 - 0.065 13.0 0.2 0.19 11.5 0.1 1.9 2 0 0 2 2 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CBZ37805.1 - 0.065 12.9 0.1 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 CBZ37805.1 - 0.071 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_17 PF13207.6 CBZ37805.1 - 0.1 13.1 1.5 1.3 9.4 0.2 3.1 1 1 2 3 3 3 0 AAA domain SET PF00856.28 CBZ37806.1 - 0.009 16.4 0.0 0.016 15.6 0.0 1.4 1 1 0 1 1 1 1 SET domain AAA PF00004.29 CBZ37807.1 - 1.5e-49 167.8 0.0 1.1e-37 129.4 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CBZ37807.1 - 1.8e-15 57.1 0.2 4.7e-15 55.8 0.2 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 CBZ37807.1 - 1.4e-12 48.4 3.1 3.4e-05 24.3 0.1 4.4 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 CBZ37807.1 - 7.5e-09 36.0 0.2 0.011 16.0 0.0 3.9 3 1 1 4 4 3 2 AAA domain DUF815 PF05673.13 CBZ37807.1 - 2.8e-07 29.9 0.0 0.00027 20.2 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 CBZ37807.1 - 4.8e-07 29.5 0.0 0.037 13.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 CBZ37807.1 - 2.6e-06 27.7 0.0 0.014 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATP-synt_ab PF00006.25 CBZ37807.1 - 2.3e-05 24.2 0.0 0.073 12.7 0.0 2.4 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 CBZ37807.1 - 4.4e-05 23.5 0.2 0.083 12.9 0.0 3.4 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CBZ37807.1 - 5.2e-05 23.3 0.0 0.0078 16.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CBZ37807.1 - 9.8e-05 22.9 0.0 0.43 11.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter AAA_29 PF13555.6 CBZ37807.1 - 0.00013 21.7 0.0 0.29 10.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 CBZ37807.1 - 0.00016 22.0 0.0 0.068 13.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.6 CBZ37807.1 - 0.00019 21.8 0.1 0.089 13.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CBZ37807.1 - 0.00049 20.2 0.0 0.0019 18.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 CBZ37807.1 - 0.00056 19.9 0.0 0.58 10.0 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain RsgA_GTPase PF03193.16 CBZ37807.1 - 0.0011 18.9 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase TsaE PF02367.17 CBZ37807.1 - 0.0012 18.8 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CBZ37807.1 - 0.0014 18.2 6.9 3.3 7.2 0.0 5.6 4 1 2 6 6 6 1 AAA domain Sigma54_activat PF00158.26 CBZ37807.1 - 0.0017 18.1 0.1 3.1 7.5 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 CBZ37807.1 - 0.0018 18.1 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.12 CBZ37807.1 - 0.0024 17.8 1.9 3.8 7.4 0.0 3.9 3 1 0 4 4 3 1 NACHT domain ATPase_2 PF01637.18 CBZ37807.1 - 0.0024 17.8 0.1 0.064 13.2 0.0 2.5 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 CBZ37807.1 - 0.0035 16.4 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Vps4_C PF09336.10 CBZ37807.1 - 0.0039 17.1 0.0 0.012 15.6 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_28 PF13521.6 CBZ37807.1 - 0.004 17.4 0.0 1.9 8.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBZ37807.1 - 0.0041 16.5 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 CBZ37807.1 - 0.0055 17.2 0.1 4.8 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_lid_3 PF17862.1 CBZ37807.1 - 0.0091 15.8 0.0 0.053 13.3 0.0 2.3 2 0 0 2 2 2 1 AAA+ lid domain Sigma54_activ_2 PF14532.6 CBZ37807.1 - 0.0098 16.0 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.12 CBZ37807.1 - 0.013 15.2 0.0 4.9 6.9 0.0 2.8 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CBZ37807.1 - 0.014 15.1 0.2 2 8.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 CBZ37807.1 - 0.024 14.0 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 CBZ37807.1 - 0.037 13.9 0.2 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 NTPase Bac_DnaA PF00308.18 CBZ37807.1 - 0.054 13.3 0.0 7 6.4 0.0 2.6 3 0 0 3 3 2 0 Bacterial dnaA protein FtsK_SpoIIIE PF01580.18 CBZ37807.1 - 0.06 12.7 0.3 0.15 11.4 0.0 1.8 2 0 0 2 2 1 0 FtsK/SpoIIIE family NB-ARC PF00931.22 CBZ37807.1 - 0.078 12.1 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 CBZ37807.1 - 0.079 13.5 0.0 6.2 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CBZ37807.1 - 0.093 12.0 0.0 9.4 5.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin TIP49 PF06068.13 CBZ37807.1 - 0.13 11.4 0.0 4 6.5 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain BBIP10 PF14777.6 CBZ37807.1 - 0.15 11.6 0.0 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Cilia BBSome complex subunit 10 RHD3 PF05879.12 CBZ37808.1 - 0.15 10.2 0.0 0.23 9.6 0.0 1.2 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) LicD PF04991.13 CBZ37809.1 - 4.5e-07 30.2 0.1 0.0049 17.0 0.3 2.1 1 1 1 2 2 2 2 LicD family Deltaretro_Tax PF05599.11 CBZ37809.1 - 0.011 16.2 0.0 0.027 15.0 0.0 1.7 1 0 0 1 1 1 0 Deltaretrovirus Tax protein NTP_transf_2 PF01909.23 CBZ37809.1 - 0.094 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase domain PDCD2_C PF04194.13 CBZ37810.1 - 3.7e-25 89.0 1.3 9.6e-25 87.7 0.0 2.2 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Elf1 PF05129.13 CBZ37810.1 - 0.013 15.6 0.7 0.067 13.2 0.2 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RRN7 PF11781.8 CBZ37810.1 - 0.058 13.1 1.8 0.6 9.8 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Zn-ribbon_8 PF09723.10 CBZ37810.1 - 0.12 12.5 2.4 22 5.2 0.2 3.5 3 0 0 3 3 3 0 Zinc ribbon domain Stc1 PF12898.7 CBZ37810.1 - 0.25 11.9 3.1 0.51 10.9 0.3 2.7 2 1 0 2 2 2 0 Stc1 domain CpXC PF14353.6 CBZ37810.1 - 5.2 7.1 5.6 91 3.1 0.0 3.0 2 1 0 2 2 2 0 CpXC protein Lar_restr_allev PF14354.6 CBZ37810.1 - 8.1 6.9 6.8 14 6.2 0.1 3.1 2 1 1 3 3 3 0 Restriction alleviation protein Lar Ank_2 PF12796.7 CBZ37811.1 - 2.9e-31 107.9 0.8 2.1e-14 53.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ37811.1 - 6e-23 80.9 0.4 5.6e-06 26.8 0.1 5.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CBZ37811.1 - 7.8e-23 79.9 2.4 9.8e-06 25.8 0.1 5.3 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 CBZ37811.1 - 8.8e-21 71.8 0.4 5.8e-05 23.2 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CBZ37811.1 - 4.5e-19 68.2 6.2 7.5e-08 32.5 0.2 4.4 1 1 3 4 4 4 3 Ankyrin repeats (many copies) DUF3372 PF11852.8 CBZ37811.1 - 0.092 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) DUF2065 PF09838.9 CBZ37811.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) PI3_PI4_kinase PF00454.27 CBZ37814.1 - 3.3e-36 125.4 0.0 8.9e-25 87.9 0.0 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 CBZ37814.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) PfkB PF00294.24 CBZ37815.1 - 2.1e-44 152.0 0.1 4.5e-43 147.7 0.1 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Complex1_LYR PF05347.15 CBZ37816.1 - 2.1e-09 37.3 0.8 3.2e-09 36.7 0.8 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF3336 PF11815.8 CBZ37817.1 - 6.6e-20 71.2 0.0 1.1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CBZ37817.1 - 8.9e-11 42.4 0.3 1.7e-10 41.4 0.3 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Metallophos PF00149.28 CBZ37818.1 - 1.1e-07 32.5 0.0 2.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CBZ37818.1 - 0.00053 20.2 0.0 0.019 15.2 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain VirB3 PF05101.13 CBZ37820.1 - 0.28 11.5 3.4 0.24 11.6 1.9 1.7 1 1 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Ribosomal_L21e PF01157.18 CBZ37821.1 - 2.4e-40 136.5 2.6 3.6e-40 135.9 2.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e EMP70 PF02990.16 CBZ37822.1 - 7.8e-134 447.2 0.5 9.7e-134 446.9 0.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ATP-synt_ab PF00006.25 CBZ37823.1 - 2.2e-105 351.0 0.0 3.5e-105 350.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CBZ37823.1 - 2.5e-44 150.0 0.2 6.2e-44 148.7 0.0 1.8 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CBZ37823.1 - 1.7e-15 57.3 1.5 1.7e-15 57.3 1.5 2.6 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain DUF2737 PF10930.8 CBZ37823.1 - 0.1 12.2 0.1 5.9 6.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2737) DUF2118 PF09891.9 CBZ37823.1 - 0.11 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Ribosomal_L13 PF00572.18 CBZ37824.1 - 4.1e-29 101.4 0.1 5.3e-29 101.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ins_P5_2-kin PF06090.12 CBZ37826.1 - 8e-25 88.0 0.0 1e-24 87.6 0.0 1.3 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase TMIE PF16038.5 CBZ37827.1 - 1.6 8.6 4.1 3.2 7.7 0.2 2.3 2 0 0 2 2 2 0 TMIE protein DUF501 PF04417.12 CBZ37828.1 - 2.7e-29 101.8 0.4 4.5e-29 101.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF501) Aminotran_1_2 PF00155.21 CBZ37830.1 - 2e-44 152.3 0.0 2.4e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II LIM PF00412.22 CBZ37832.1 - 0.051 13.8 9.8 0.11 12.8 8.3 2.2 2 0 0 2 2 2 0 LIM domain zinc_ribbon_6 PF14599.6 CBZ37832.1 - 1.2 9.2 5.8 3.5 7.7 5.8 1.8 1 0 0 1 1 1 0 Zinc-ribbon Actin PF00022.19 CBZ37833.1 - 1.3e-30 106.4 0.0 3.4e-30 105.0 0.0 1.6 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CBZ37833.1 - 0.0013 19.1 0.0 0.0019 18.6 0.0 1.4 1 1 0 1 1 1 1 Cell division protein FtsA TetR_C_6 PF13977.6 CBZ37833.1 - 0.013 15.7 0.3 3.2 8.0 0.0 2.8 2 1 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal Ribosomal_60s PF00428.19 CBZ37834.1 - 0.12 13.0 0.9 0.23 12.0 0.9 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein PGM_PMM_I PF02878.16 CBZ37835.1 - 1.5e-37 128.4 0.0 3.2e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CBZ37835.1 - 1.3e-20 73.9 0.0 5e-20 72.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CBZ37835.1 - 1.5e-15 57.3 0.1 2.4e-14 53.5 0.1 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CBZ37835.1 - 5e-06 26.6 0.0 1.8e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ANAPC4_WD40 PF12894.7 CBZ37836.1 - 0.041 14.2 0.0 40 4.6 0.0 4.7 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L14 PF00238.19 CBZ37839.1 - 2.1e-21 76.3 0.1 3.4e-21 75.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TPR_1 PF00515.28 CBZ37840.1 - 2e-07 30.5 8.2 0.091 12.6 0.1 3.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ37840.1 - 9.3e-07 28.5 10.2 0.095 12.9 0.2 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ37840.1 - 0.00026 20.6 0.2 0.019 14.6 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 CBZ37840.1 - 0.00033 20.9 5.7 0.53 10.6 1.6 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ37840.1 - 0.0028 18.1 0.1 0.38 11.3 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ37840.1 - 0.011 15.9 5.8 1.3 9.3 1.3 3.7 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CBZ37840.1 - 0.037 14.4 0.1 15 6.3 0.1 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ37840.1 - 0.11 13.4 2.4 31 5.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ37840.1 - 0.11 12.6 0.1 4.2 7.6 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ37840.1 - 0.15 12.4 7.0 3.5 8.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ37840.1 - 0.21 12.3 4.9 17 6.3 1.3 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat Toxin_36 PF10550.9 CBZ37840.1 - 1.1 10.8 4.1 7.6 8.2 1.0 2.7 2 0 0 2 2 2 0 Conantokin-G mollusc-toxin TPR_16 PF13432.6 CBZ37840.1 - 1.2 9.8 11.1 12 6.6 0.1 3.6 3 1 1 4 4 3 0 Tetratricopeptide repeat DUF745 PF05335.13 CBZ37841.1 - 0.0015 18.3 8.6 0.0015 18.3 8.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF745) MscS_porin PF12795.7 CBZ37841.1 - 0.0064 16.1 13.6 0.0064 16.1 13.6 1.8 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain Nup88 PF10168.9 CBZ37841.1 - 0.033 12.0 4.3 0.043 11.6 4.3 1.1 1 0 0 1 1 1 0 Nuclear pore component V_ATPase_I PF01496.19 CBZ37841.1 - 0.069 11.1 1.0 0.068 11.1 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.11 CBZ37841.1 - 0.11 11.0 5.4 0.12 10.8 5.4 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 CBZ37841.1 - 0.14 11.5 7.2 0.19 11.0 7.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CBZ37841.1 - 0.17 10.7 14.6 0.05 12.5 10.8 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein LMBR1 PF04791.16 CBZ37841.1 - 0.36 9.7 0.6 0.43 9.4 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein TSC22 PF01166.18 CBZ37841.1 - 0.41 11.0 0.0 0.41 11.0 0.0 2.7 3 1 1 4 4 4 0 TSC-22/dip/bun family Atg14 PF10186.9 CBZ37841.1 - 1.5 7.8 14.5 0.06 12.4 7.9 1.9 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF724 PF05266.14 CBZ37841.1 - 2.1 8.1 8.3 1.6 8.5 4.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF45 PF01863.17 CBZ37841.1 - 2.5 8.1 7.4 21 5.1 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 MPS2 PF17060.5 CBZ37841.1 - 3.2 6.9 6.7 1 8.5 3.9 1.5 2 0 0 2 2 2 0 Monopolar spindle protein 2 Acyl-CoA_dh_2 PF08028.11 CBZ37841.1 - 5.6 7.2 17.5 0.24 11.7 10.4 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain OmpH PF03938.14 CBZ37841.1 - 7.6 6.9 11.3 16 5.9 11.3 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DHR10 PF18595.1 CBZ37841.1 - 9.4 6.3 29.2 0.49 10.5 18.0 3.1 2 2 2 4 4 4 0 Designed helical repeat protein 10 domain RP853 PF17542.2 CBZ37842.1 - 0.09 11.9 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized RP853 MIP PF00230.20 CBZ37843.1 - 6.5e-35 120.9 18.6 3.9e-34 118.3 18.6 1.8 1 1 0 1 1 1 1 Major intrinsic protein Transgly_assoc PF04226.13 CBZ37843.1 - 1.5 9.2 0.0 1.5 9.2 0.0 3.6 4 0 0 4 4 4 0 Transglycosylase associated protein LSM PF01423.22 CBZ37844.1 - 1.1e-12 47.4 0.1 1.4e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ37844.1 - 0.013 15.7 0.1 0.02 15.1 0.1 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Cu_amine_oxidN1 PF07833.11 CBZ37844.1 - 0.13 12.7 0.0 0.2 12.2 0.0 1.2 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain DnaJ PF00226.31 CBZ37845.1 - 9.2e-19 67.3 0.0 1.8e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain AAA_6 PF12774.7 CBZ37846.1 - 3.4e-152 506.1 0.0 1.1e-151 504.4 0.0 2.0 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 CBZ37846.1 - 5.5e-135 451.2 1.3 5.5e-135 451.2 1.3 2.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 CBZ37846.1 - 1.9e-114 382.9 8.2 1.9e-114 382.9 8.2 4.4 6 0 0 6 6 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 CBZ37846.1 - 7.7e-103 343.3 0.0 2.1e-102 341.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 CBZ37846.1 - 5.1e-83 278.8 0.2 5.1e-83 278.8 0.2 2.1 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 CBZ37846.1 - 6.3e-75 251.1 0.0 6.3e-75 251.1 0.0 3.0 4 0 0 4 4 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ37846.1 - 2.7e-65 219.3 5.4 7.9e-60 201.5 0.1 4.8 4 1 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ37846.1 - 7.3e-50 169.0 0.0 1.8e-49 167.7 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ37846.1 - 9.9e-43 145.0 0.0 2e-41 140.8 0.1 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBZ37846.1 - 1.6e-41 142.5 8.1 2.6e-41 141.8 8.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CBZ37846.1 - 1.8e-22 79.8 0.4 2.4e-07 30.8 0.0 7.0 5 2 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 CBZ37846.1 - 6e-21 74.9 0.0 2.8e-20 72.7 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBZ37846.1 - 1.3e-14 54.2 0.0 5.8e-14 52.1 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CBZ37846.1 - 2.3e-10 41.1 1.2 0.048 14.0 0.0 6.7 5 0 0 5 5 5 2 AAA ATPase domain AAA PF00004.29 CBZ37846.1 - 7.9e-09 36.0 2.2 0.78 10.2 0.0 6.3 5 0 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CBZ37846.1 - 3.4e-05 24.1 4.8 0.43 10.8 0.0 5.7 6 0 0 6 6 4 1 AAA domain AAA_18 PF13238.6 CBZ37846.1 - 0.00033 21.2 0.2 4 8.0 0.0 4.7 4 0 0 4 4 3 1 AAA domain RsgA_GTPase PF03193.16 CBZ37846.1 - 0.0007 19.5 1.0 0.029 14.3 0.1 3.5 3 0 0 3 3 3 1 RsgA GTPase AAA_30 PF13604.6 CBZ37846.1 - 0.003 17.3 2.0 3 7.5 0.1 4.0 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.6 CBZ37846.1 - 0.0031 17.2 0.7 0.085 12.6 0.0 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 CBZ37846.1 - 0.011 15.7 0.4 2.4 8.0 0.0 3.5 4 0 0 4 4 2 0 Rad17 P-loop domain AAA_33 PF13671.6 CBZ37846.1 - 0.014 15.5 8.9 0.86 9.8 0.0 5.0 6 0 0 6 6 4 0 AAA domain RNA_helicase PF00910.22 CBZ37846.1 - 0.036 14.5 2.1 2.7 8.4 0.0 3.4 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 CBZ37846.1 - 0.086 13.4 4.2 1.3 9.5 0.0 4.2 4 0 0 4 4 2 0 ABC transporter AAA_lid_7 PF17867.1 CBZ37846.1 - 0.089 13.0 0.0 9.4 6.5 0.0 3.9 3 0 0 3 3 3 0 Midasin AAA lid domain DUF1612 PF07756.12 CBZ37846.1 - 0.2 11.9 4.4 0.74 10.1 4.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) SMC_N PF02463.19 CBZ37846.1 - 0.23 10.9 0.1 3.2 7.1 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 CBZ37846.1 - 0.27 11.5 4.4 32 4.9 0.0 4.2 4 0 0 4 4 3 0 AAA domain Carla_C4 PF01623.17 CBZ37846.1 - 0.7 9.9 2.0 3.1 7.8 0.2 2.5 2 0 0 2 2 2 0 Carlavirus putative nucleic acid binding protein T2SSE PF00437.20 CBZ37846.1 - 2.4 7.2 8.3 3 6.8 0.1 3.8 4 0 0 4 4 4 0 Type II/IV secretion system protein DUF1512 PF07431.12 CBZ37847.1 - 0.038 13.0 0.0 0.073 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) HATPase_c PF02518.26 CBZ37848.1 - 2.2e-10 41.0 0.0 4.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pet191_N PF10203.9 CBZ37849.1 - 4.4e-09 36.5 2.6 6.5e-09 36.0 2.6 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 NIF PF03031.18 CBZ37850.1 - 3.5e-26 91.8 0.0 5.3e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF705 PF05152.12 CBZ37850.1 - 2.3e-05 24.0 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) HAD PF12710.7 CBZ37850.1 - 0.76 10.1 3.0 7.8 6.9 0.1 3.0 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase LBP_BPI_CETP_C PF02886.17 CBZ37851.1 - 0.0015 18.0 0.4 0.028 13.9 0.0 2.6 3 0 0 3 3 3 1 LBP / BPI / CETP family, C-terminal domain PI3_PI4_kinase PF00454.27 CBZ37852.1 - 1.9e-56 191.7 0.0 5.7e-56 190.1 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CBZ37852.1 - 1.2e-21 77.4 0.1 2.6e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 CBZ37852.1 - 1.1e-14 54.7 0.6 7.2e-14 52.0 0.6 2.6 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 CBZ37852.1 - 4.3e-13 49.5 4.9 1.3e-12 47.9 0.2 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) FATC PF02260.20 CBZ37852.1 - 2.3e-11 43.3 0.4 1.2e-10 41.0 0.0 2.3 2 0 0 2 2 2 1 FATC domain PDZ_6 PF17820.1 CBZ37852.1 - 8.8e-05 22.3 0.2 0.00025 20.8 0.2 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBZ37852.1 - 0.00039 20.7 0.1 0.00094 19.5 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PUF PF00806.19 CBZ37852.1 - 0.22 11.3 0.5 29 4.6 0.0 3.3 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat IFRD PF05004.13 CBZ37852.1 - 0.37 9.8 3.8 0.54 9.3 0.1 3.1 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) UPF0184 PF03670.13 CBZ37853.1 - 0.055 13.9 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Fmp27_WPPW PF10359.9 CBZ37853.1 - 0.076 11.9 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain PIG-Y PF15159.6 CBZ37855.1 - 1.6e-09 38.5 1.9 2e-09 38.2 1.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y HECT PF00632.25 CBZ37856.1 - 2e-48 165.5 0.0 5e-48 164.2 0.0 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.20 CBZ37857.1 - 1.9e-73 247.8 5.0 2.6e-73 247.4 5.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CBZ37857.1 - 1.3e-07 31.9 0.0 3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Vac14_Fab1_bd PF12755.7 CBZ37857.1 - 0.041 14.5 0.6 2.3 8.9 0.0 3.4 2 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CBZ37857.1 - 0.092 12.3 0.7 13 5.2 0.0 3.4 3 1 0 3 3 3 0 CLASP N terminal Ribosomal_L7Ae PF01248.26 CBZ37858.1 - 1e-19 70.0 0.4 1.3e-19 69.7 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Rgp1 PF08737.10 CBZ37859.1 - 1.5e-10 40.8 0.0 0.00019 20.7 0.0 2.1 2 0 0 2 2 2 2 Rgp1 T4BSS_DotH_IcmK PF12293.8 CBZ37859.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative outer membrane core complex of type IVb secretion Arrestin_N PF00339.29 CBZ37859.1 - 0.12 12.4 0.2 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Peptidase_C78 PF07910.13 CBZ37860.1 - 6.7e-48 163.0 0.0 9.3e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 CBZ37860.1 - 0.07 12.5 0.1 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 Peptidase family C54 DUF4964 PF16334.5 CBZ37860.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) DUF445 PF04286.12 CBZ37862.1 - 0.012 15.5 0.4 0.014 15.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) FANCI_S1-cap PF14674.6 CBZ37862.1 - 0.063 13.4 0.6 1.7 8.8 0.1 2.4 2 0 0 2 2 2 0 FANCI solenoid 1 cap MGC-24 PF05283.11 CBZ37862.1 - 0.067 13.6 1.0 0.12 12.8 1.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin HrpB_C PF08482.10 CBZ37862.1 - 0.1 13.0 0.3 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 ATP-dependent helicase C-terminal TEX33 PF15400.6 CBZ37862.1 - 0.26 11.8 0.8 2.8 8.4 0.1 2.2 1 1 1 2 2 2 0 Testis-expressed sequence 33 protein family U3snoRNP10 PF12397.8 CBZ37862.1 - 7.3 7.0 7.1 2.1 8.7 0.8 3.0 2 2 1 3 3 3 0 U3 small nucleolar RNA-associated protein 10 Prenyltrans PF00432.21 CBZ37863.1 - 2.3e-71 235.2 16.4 1.2e-14 53.7 0.4 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CBZ37863.1 - 5e-08 32.4 0.0 0.11 11.6 0.0 4.2 1 1 3 4 4 4 3 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 CBZ37863.1 - 8.9e-06 25.0 0.6 0.00045 19.4 0.0 2.7 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 CBZ37863.1 - 0.073 12.1 0.1 0.84 8.6 0.0 2.7 3 2 1 4 4 4 0 A-macroglobulin TED domain UCH PF00443.29 CBZ37866.1 - 9.7e-37 126.8 0.1 1.4e-36 126.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ37866.1 - 5.1e-13 49.3 0.0 1.8e-12 47.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CBZ37866.1 - 0.047 13.2 0.4 0.11 11.9 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Casc1_N PF15927.5 CBZ37867.1 - 1.1e-09 38.4 7.6 1.2e-08 35.0 7.6 2.1 1 1 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus SLT_L PF14718.6 CBZ37867.1 - 0.13 12.4 1.1 0.35 11.0 1.1 1.7 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain FapA PF03961.13 CBZ37867.1 - 0.45 9.0 3.1 20 3.7 0.0 3.0 3 0 0 3 3 3 0 Flagellar Assembly Protein A DnaJ PF00226.31 CBZ37868.1 - 4.2e-07 30.0 0.1 2.3e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 DnaJ domain GRIP PF01465.20 CBZ37869.1 - 3.8e-11 42.7 0.2 9.6e-11 41.4 0.2 1.8 1 0 0 1 1 1 1 GRIP domain MPS2 PF17060.5 CBZ37869.1 - 0.0032 16.8 5.8 0.022 14.1 2.7 2.7 3 0 0 3 3 3 1 Monopolar spindle protein 2 DUF4618 PF15397.6 CBZ37869.1 - 0.0052 16.2 0.0 0.0052 16.2 0.0 3.8 3 1 0 3 3 2 2 Domain of unknown function (DUF4618) TPR_MLP1_2 PF07926.12 CBZ37869.1 - 0.03 14.4 1.3 0.03 14.4 1.3 5.1 4 1 0 5 5 5 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CBZ37869.1 - 0.06 12.2 0.2 0.06 12.2 0.2 3.6 3 1 0 3 3 3 0 Spc7 kinetochore protein Filament PF00038.21 CBZ37869.1 - 0.069 12.7 33.7 0.032 13.8 11.8 4.5 4 1 1 5 5 5 0 Intermediate filament protein Prominin PF05478.11 CBZ37869.1 - 0.071 11.1 12.4 0.015 13.3 8.9 1.5 2 0 0 2 2 2 0 Prominin PKcGMP_CC PF16808.5 CBZ37869.1 - 0.24 11.3 8.7 2.7 7.9 0.0 3.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase CorA PF01544.18 CBZ37869.1 - 0.4 10.0 8.7 0.33 10.2 5.1 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein GAS PF13851.6 CBZ37869.1 - 0.47 9.8 37.5 2.8 7.2 0.5 4.2 4 0 0 4 4 4 0 Growth-arrest specific micro-tubule binding LOH1CR12 PF10158.9 CBZ37869.1 - 0.59 10.1 7.1 9.2 6.3 0.9 3.1 3 0 0 3 3 3 0 Tumour suppressor protein Peptidase_M13 PF01431.21 CBZ37869.1 - 0.74 9.4 5.2 1.9 8.1 0.2 2.3 2 0 0 2 2 2 0 Peptidase family M13 CCDC53 PF10152.9 CBZ37869.1 - 1 9.8 12.4 4.5 7.7 8.7 2.6 1 1 1 2 2 2 0 Subunit CCDC53 of WASH complex SPATA9 PF15824.5 CBZ37869.1 - 1.3 8.3 4.7 1 8.6 3.1 1.6 2 0 0 2 2 2 0 Spermatogenesis-associated protein 9 TSC22 PF01166.18 CBZ37869.1 - 1.3 9.4 7.9 14 6.1 0.0 4.3 4 1 1 5 5 4 0 TSC-22/dip/bun family FAM184 PF15665.5 CBZ37869.1 - 1.8 8.3 36.2 0.37 10.5 0.4 4.2 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B HIP1_clath_bdg PF16515.5 CBZ37869.1 - 3.5 8.3 42.8 1 10.0 0.7 5.4 4 1 1 5 5 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 LURAP PF14854.6 CBZ37869.1 - 4.6 7.2 8.0 0.24 11.4 0.6 2.8 3 1 1 4 4 3 0 Leucine rich adaptor protein DnaB_bind PF10410.9 CBZ37870.1 - 0.26 11.5 1.9 5.3 7.3 0.0 2.6 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase 40S_SA_C PF16122.5 CBZ37870.1 - 3 9.2 6.4 3.3 9.1 2.7 2.5 2 1 0 2 2 2 0 40S ribosomal protein SA C-terminus Peptidase_C50 PF03568.17 CBZ37871.1 - 0.083 12.0 0.1 0.59 9.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase family C50 Abhydrolase_1 PF00561.20 CBZ37872.1 - 6.7e-06 25.9 0.0 0.001 18.8 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBZ37872.1 - 4.5e-05 24.2 0.3 5.8e-05 23.8 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CBZ37872.1 - 0.00043 19.6 0.0 0.00059 19.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EMC1_C PF07774.13 CBZ37873.1 - 3.4e-49 167.4 0.0 1.1e-48 165.8 0.0 1.9 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal DCB PF16213.5 CBZ37873.1 - 0.089 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 PQQ_3 PF13570.6 CBZ37873.1 - 2.7 8.6 6.6 2.5 8.7 0.2 3.9 3 0 0 3 3 3 0 PQQ-like domain DUF4743 PF15916.5 CBZ37874.1 - 0.3 11.0 2.5 0.18 11.8 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4743) REPA_OB_2 PF16900.5 CBZ37875.1 - 0.0073 16.2 0.0 0.022 14.7 0.0 1.8 1 1 0 1 1 1 1 Replication protein A OB domain Gag_spuma PF03276.14 CBZ37875.1 - 0.15 10.5 0.1 0.23 9.8 0.1 1.2 1 0 0 1 1 1 0 Spumavirus gag protein AAA_6 PF12774.7 CBZ37876.1 - 1.7e-127 424.9 0.1 1e-126 422.4 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ37876.1 - 3.9e-108 362.1 2.7 3.9e-108 362.1 2.7 5.0 6 0 0 6 6 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CBZ37876.1 - 2e-64 216.7 0.1 2e-64 216.7 0.1 4.0 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 CBZ37876.1 - 6.1e-45 153.6 2.5 3.5e-43 147.8 0.0 3.7 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 DHC_N1 PF08385.12 CBZ37876.1 - 5.5e-38 130.9 2.2 6.6e-37 127.4 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_5 PF07728.14 CBZ37876.1 - 1.5e-33 115.7 0.0 3.6e-21 75.6 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 CBZ37876.1 - 3.8e-31 107.6 0.0 4.6e-30 104.2 0.0 3.1 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 CBZ37876.1 - 5.3e-29 101.0 3.5 4.8e-24 84.9 0.0 4.6 5 0 0 5 5 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ37876.1 - 6.5e-29 100.9 0.0 1.3e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 CBZ37876.1 - 9.7e-25 87.4 0.0 3.7e-24 85.5 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain MT PF12777.7 CBZ37876.1 - 2.3e-24 86.1 12.3 5.5e-24 84.8 12.3 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_16 PF13191.6 CBZ37876.1 - 3.4e-15 56.9 0.0 1.4e-05 25.5 0.0 6.0 4 0 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 CBZ37876.1 - 1.4e-11 44.8 0.1 0.00083 19.6 0.0 4.8 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 CBZ37876.1 - 2.1e-10 41.1 2.8 0.028 14.9 0.0 4.4 4 0 0 4 4 3 3 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CBZ37876.1 - 1.6e-07 31.2 0.6 0.0016 18.2 0.0 4.1 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 CBZ37876.1 - 3.5e-07 30.6 0.0 0.13 12.6 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_24 PF13479.6 CBZ37876.1 - 9.8e-07 28.7 0.0 0.11 12.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CBZ37876.1 - 1.2e-06 28.8 0.0 0.12 12.6 0.0 4.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 CBZ37876.1 - 3.4e-06 27.6 6.2 0.0024 18.4 0.0 4.5 4 0 0 4 4 2 2 ABC transporter RsgA_GTPase PF03193.16 CBZ37876.1 - 4.1e-06 26.8 1.8 0.00094 19.1 0.0 3.1 3 0 0 3 3 2 1 RsgA GTPase AAA_33 PF13671.6 CBZ37876.1 - 1e-05 25.8 0.1 0.094 12.9 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 CBZ37876.1 - 1.3e-05 25.7 0.7 0.056 14.0 0.0 4.8 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.17 CBZ37876.1 - 2.4e-05 24.1 0.3 0.089 12.5 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein NACHT PF05729.12 CBZ37876.1 - 8.3e-05 22.6 0.8 0.37 10.7 0.0 3.2 3 0 0 3 3 2 2 NACHT domain AAA_14 PF13173.6 CBZ37876.1 - 0.00016 21.7 0.0 0.17 11.9 0.0 3.9 3 0 0 3 3 3 1 AAA domain SRPRB PF09439.10 CBZ37876.1 - 0.00052 19.5 1.3 0.023 14.2 0.0 3.1 3 0 0 3 3 2 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 CBZ37876.1 - 0.00063 19.4 0.6 0.033 13.9 0.0 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CBZ37876.1 - 0.00066 19.4 0.0 0.17 11.6 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Fez1 PF06818.15 CBZ37876.1 - 0.0011 19.5 5.2 0.0011 19.5 5.2 5.2 6 0 0 6 6 4 1 Fez1 AAA_25 PF13481.6 CBZ37876.1 - 0.0014 18.3 0.9 2.3 7.7 0.0 4.4 5 0 0 5 5 3 1 AAA domain TsaE PF02367.17 CBZ37876.1 - 0.0014 18.6 0.1 0.57 10.2 0.0 3.9 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Laminin_II PF06009.12 CBZ37876.1 - 0.0018 18.3 2.8 0.0018 18.3 2.8 4.9 5 0 0 5 5 3 1 Laminin Domain II T2SSE PF00437.20 CBZ37876.1 - 0.0025 16.9 0.1 0.11 11.6 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein Rad17 PF03215.15 CBZ37876.1 - 0.0028 17.6 0.2 0.84 9.5 0.0 3.5 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_21 PF13304.6 CBZ37876.1 - 0.0032 17.3 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 CBZ37876.1 - 0.0036 16.7 0.0 5 6.4 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI CbiA PF01656.23 CBZ37876.1 - 0.0037 17.3 0.1 27 4.8 0.1 3.8 2 1 1 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Roc PF08477.13 CBZ37876.1 - 0.006 16.8 0.2 3.1 8.1 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 CBZ37876.1 - 0.0077 15.2 0.5 0.11 11.5 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CBZ37876.1 - 0.012 15.2 3.1 0.92 9.1 0.0 3.2 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 CBZ37876.1 - 0.016 14.4 0.2 1.5 8.0 0.0 3.2 3 0 0 3 3 2 0 NB-ARC domain IIGP PF05049.13 CBZ37876.1 - 0.017 14.2 0.8 0.054 12.6 0.0 2.1 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_lid_7 PF17867.1 CBZ37876.1 - 0.018 15.2 1.8 0.12 12.6 0.0 3.4 4 0 0 4 4 1 0 Midasin AAA lid domain AAA_PrkA PF08298.11 CBZ37876.1 - 0.019 13.9 0.0 0.058 12.3 0.0 1.7 2 0 0 2 2 1 0 PrkA AAA domain MMR_HSR1 PF01926.23 CBZ37876.1 - 0.03 14.4 0.3 3.9 7.6 0.1 3.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase Septin PF00735.18 CBZ37876.1 - 0.031 13.6 0.3 5.7 6.1 0.0 2.8 3 0 0 3 3 2 0 Septin Zeta_toxin PF06414.12 CBZ37876.1 - 0.032 13.5 0.0 1.5 8.0 0.0 3.4 4 0 0 4 4 3 0 Zeta toxin ATP_bind_1 PF03029.17 CBZ37876.1 - 0.036 13.9 1.4 1.4 8.7 0.0 3.5 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Guanylate_kin PF00625.21 CBZ37876.1 - 0.041 13.6 8.9 0.35 10.5 0.0 4.0 4 0 0 4 4 3 0 Guanylate kinase MobB PF03205.14 CBZ37876.1 - 0.097 12.6 0.3 7.6 6.4 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ploopntkinase3 PF18751.1 CBZ37876.1 - 0.12 12.2 0.0 0.55 10.1 0.0 2.1 2 0 0 2 2 1 0 P-loop Nucleotide Kinase3 ATPase_2 PF01637.18 CBZ37876.1 - 0.19 11.6 0.0 0.19 11.6 0.0 4.3 5 0 0 5 5 3 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 CBZ37876.1 - 0.84 10.1 0.0 0.84 10.1 0.0 7.5 7 0 0 7 7 7 0 AAA domain V_ATPase_I PF01496.19 CBZ37876.1 - 1.3 6.9 13.7 0.5 8.2 3.3 2.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family G-alpha PF00503.20 CBZ37876.1 - 2.7 7.1 7.5 0.9 8.6 0.1 3.5 4 0 0 4 4 4 0 G-protein alpha subunit zf-CCHC_3 PF13917.6 CBZ37877.1 - 9.5e-13 47.9 1.4 1.6e-12 47.1 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 CBZ37877.1 - 0.00094 19.6 0.8 0.00094 19.6 0.8 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G zf-CCHC PF00098.23 CBZ37877.1 - 0.05 13.7 1.0 0.076 13.1 0.2 1.7 2 0 0 2 2 2 0 Zinc knuckle Fam20C PF06702.12 CBZ37878.1 - 5.4e-06 26.4 0.1 0.021 14.7 0.0 2.3 2 0 0 2 2 2 2 Golgi casein kinase, C-terminal, Fam20 HipA_C PF07804.12 CBZ37878.1 - 0.02 14.6 0.0 0.069 12.8 0.0 1.8 1 1 0 1 1 1 0 HipA-like C-terminal domain Metallophos PF00149.28 CBZ37879.1 - 4e-33 115.7 0.0 5.3e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Complex1_LYR PF05347.15 CBZ37882.1 - 0.031 14.3 0.1 0.073 13.1 0.1 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Robl_LC7 PF03259.17 CBZ37883.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.6 1 1 0 1 1 1 0 Roadblock/LC7 domain BRCT PF00533.26 CBZ37884.1 - 5.2e-08 33.1 0.0 1.1e-05 25.7 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain FHA PF00498.26 CBZ37884.1 - 6.4e-07 29.6 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 CBZ37884.1 - 4.1e-06 26.6 0.0 8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 CBZ37884.1 - 4.3e-05 23.4 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CBZ37884.1 - 6.5e-05 23.3 0.0 0.14 12.6 0.0 2.8 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain Glycos_trans_3N PF02885.17 CBZ37884.1 - 0.059 13.2 5.7 1.2 9.1 0.0 3.6 4 0 0 4 4 4 0 Glycosyl transferase family, helical bundle domain KASH PF10541.9 CBZ37885.1 - 0.4 11.0 3.1 21 5.5 0.2 3.4 2 1 1 3 3 3 0 Nuclear envelope localisation domain Cullin_binding PF03556.15 CBZ37887.1 - 2.2e-16 60.4 0.7 3.5e-16 59.7 0.7 1.3 1 0 0 1 1 1 1 Cullin binding Ank_2 PF12796.7 CBZ37888.1 - 1.7e-17 63.8 1.1 2.6e-10 40.7 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ37888.1 - 1.8e-16 60.3 1.7 1e-06 29.1 0.3 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ37888.1 - 6e-14 50.8 1.5 0.016 15.7 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 CBZ37888.1 - 3.8e-09 36.6 10.9 0.003 17.9 0.1 5.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CBZ37888.1 - 3.1e-07 30.5 6.5 0.21 12.1 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeat Pox_TAP PF03355.14 CBZ37888.1 - 0.22 11.1 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Viral Trans-Activator Protein Gar1 PF04410.14 CBZ37889.1 - 6.6e-27 94.2 0.0 8e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DHHC PF01529.20 CBZ37890.1 - 1e-16 61.3 4.0 1.5e-16 60.7 4.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase zinc_ribbon_2 PF13240.6 CBZ37890.1 - 0.021 14.5 1.2 0.046 13.5 1.2 1.6 1 1 0 1 1 1 0 zinc-ribbon domain Cys_knot PF00007.22 CBZ37890.1 - 0.032 14.5 0.9 0.054 13.8 0.9 1.4 1 0 0 1 1 1 0 Cystine-knot domain COPI_C PF06957.11 CBZ37891.1 - 4.9e-98 328.5 0.0 7.5e-98 327.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 CBZ37891.1 - 2.7e-97 326.6 0.2 3.9e-97 326.1 0.2 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CBZ37891.1 - 3.5e-40 135.2 19.1 3.6e-07 30.8 0.2 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat HSDR_N PF04313.14 CBZ37891.1 - 0.024 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) TPR_14 PF13428.6 CBZ37891.1 - 0.87 10.6 8.7 36 5.5 0.6 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat LAP2alpha PF11560.8 CBZ37891.1 - 1 8.8 5.7 9.9 5.5 0.9 2.3 2 0 0 2 2 2 0 Lamina-associated polypeptide 2 alpha ESSS PF10183.9 CBZ37893.1 - 1.5e-16 60.5 8.2 3e-16 59.5 8.2 1.6 1 1 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) PI3_PI4_kinase PF00454.27 CBZ37894.1 - 3.8e-58 197.3 0.4 9.2e-58 196.0 0.1 1.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CBZ37894.1 - 2.4e-41 142.1 1.1 4.9e-41 141.1 1.1 1.6 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 CBZ37894.1 - 3.1e-28 98.1 0.6 1.1e-27 96.3 0.2 2.3 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 CBZ37894.1 - 6.2e-15 55.5 0.0 3.7e-14 52.9 0.0 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) FATC PF02260.20 CBZ37894.1 - 2.9e-11 43.0 0.4 1e-10 41.3 0.4 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CBZ37894.1 - 5.3e-05 23.1 0.7 3.4 8.2 0.0 6.4 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.6 CBZ37894.1 - 0.0055 17.1 0.0 2.2 8.7 0.0 4.8 6 0 0 6 6 6 1 HEAT repeats Cnd1 PF12717.7 CBZ37894.1 - 0.0065 16.5 0.1 0.65 10.0 0.0 4.2 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CBZ37894.1 - 0.025 15.1 0.8 6.5 7.4 0.0 4.9 5 0 0 5 5 5 0 HEAT-like repeat ADIP PF11559.8 CBZ37895.1 - 0.00027 21.1 4.5 0.00031 20.9 4.5 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding IFT57 PF10498.9 CBZ37895.1 - 0.0076 15.3 3.2 0.0073 15.3 3.2 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 JAKMIP_CC3 PF16034.5 CBZ37895.1 - 0.013 15.5 2.4 0.016 15.2 2.4 1.2 1 0 0 1 1 1 0 JAKMIP CC3 domain BRE1 PF08647.11 CBZ37895.1 - 0.013 15.5 5.7 0.013 15.5 5.7 1.5 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase HMMR_C PF15908.5 CBZ37895.1 - 0.016 15.4 2.1 0.024 14.9 2.1 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal DUF3450 PF11932.8 CBZ37895.1 - 0.02 14.2 6.3 0.018 14.4 5.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1241 PF06840.11 CBZ37895.1 - 0.03 14.0 3.2 0.04 13.6 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Lebercilin PF15619.6 CBZ37895.1 - 0.039 13.6 8.6 0.097 12.3 8.6 1.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 CBZ37895.1 - 0.041 13.4 6.7 0.066 12.7 6.7 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 GAS PF13851.6 CBZ37895.1 - 0.054 12.8 8.0 0.063 12.6 8.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF4061 PF13270.6 CBZ37895.1 - 0.06 13.7 1.4 0.17 12.2 1.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4061) Spc7 PF08317.11 CBZ37895.1 - 0.081 11.8 8.8 0.1 11.4 8.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FAM76 PF16046.5 CBZ37895.1 - 0.082 12.2 3.4 0.091 12.1 3.4 1.1 1 0 0 1 1 1 0 FAM76 protein Wtap PF17098.5 CBZ37895.1 - 0.091 12.7 5.5 0.11 12.4 5.5 1.1 1 0 0 1 1 1 0 WTAP/Mum2p family OmpH PF03938.14 CBZ37895.1 - 0.092 13.1 6.3 0.11 12.8 6.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) CLZ PF16526.5 CBZ37895.1 - 0.3 11.5 6.7 0.63 10.4 3.0 2.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FliD_N PF02465.18 CBZ37895.1 - 0.33 11.7 5.1 0.62 10.8 5.1 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus THOC7 PF05615.13 CBZ37895.1 - 0.39 11.0 8.0 0.32 11.3 5.2 1.8 1 1 1 2 2 2 0 Tho complex subunit 7 APG6_N PF17675.1 CBZ37895.1 - 1.9 9.0 10.9 6.3 7.3 10.9 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 CBZ37895.1 - 2.3 8.1 9.5 1.3 8.9 0.4 2.7 1 1 2 3 3 3 0 Septum formation initiator CENP-Q PF13094.6 CBZ37895.1 - 2.5 8.3 10.2 5.9 7.1 10.2 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4140 PF13600.6 CBZ37895.1 - 3 8.3 7.8 90 3.6 7.8 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Rcd1 PF04078.13 CBZ37896.1 - 3e-100 334.8 2.0 3.5e-100 334.6 2.0 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like V-ATPase_H_N PF03224.14 CBZ37896.1 - 0.095 12.0 0.2 1.3 8.2 0.0 2.4 1 1 1 2 2 2 0 V-ATPase subunit H RRM_1 PF00076.22 CBZ37897.1 - 2.1e-28 98.0 0.0 6.5e-14 51.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBZ37897.1 - 0.00044 20.3 0.0 3.1 7.9 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif RRM_7 PF16367.5 CBZ37897.1 - 0.00067 19.7 0.0 0.49 10.6 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif RNA_bind PF08675.11 CBZ37897.1 - 0.011 15.8 0.1 0.6 10.2 0.0 2.7 3 1 0 3 3 3 0 RNA binding domain RRM_5 PF13893.6 CBZ37897.1 - 0.12 12.0 0.0 12 5.5 0.0 2.5 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CBZ37897.1 - 0.13 12.5 1.9 5.5 7.2 0.3 3.0 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 CBZ37897.1 - 0.14 12.2 0.0 0.91 9.6 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Tmemb_170 PF10190.9 CBZ37898.1 - 0.0023 18.3 9.8 0.0028 18.0 9.8 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 TMEM239 PF15841.5 CBZ37898.1 - 0.21 11.5 2.6 0.3 11.0 2.6 1.5 1 1 0 1 1 1 0 Transmembrane protein 239 family TMEM40 PF15817.5 CBZ37898.1 - 2.4 7.9 6.6 0.66 9.7 1.2 2.1 1 1 1 2 2 2 0 Transmembrane protein 40 family FAM176 PF14851.6 CBZ37898.1 - 4.2 7.0 7.3 0.1 12.3 0.7 1.6 2 0 0 2 2 2 0 FAM176 family WD40 PF00400.32 CBZ37899.1 - 0.00015 22.4 4.7 0.04 14.8 0.0 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ37899.1 - 0.0061 16.8 0.0 13 6.2 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-bind_6 PF13921.6 CBZ37900.1 - 0.014 15.7 0.1 0.73 10.1 0.1 2.6 1 1 1 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CBZ37900.1 - 0.04 14.1 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain ARD PF03079.14 CBZ37901.1 - 1.5e-25 90.3 0.0 1.5e-25 90.3 0.0 2.1 2 0 0 2 2 2 1 ARD/ARD' family Cupin_2 PF07883.11 CBZ37901.1 - 1.5e-06 27.8 0.0 3.8e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 CBZ37901.1 - 0.00061 19.4 0.0 0.0016 18.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 CBZ37901.1 - 0.0012 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_8 PF13621.6 CBZ37901.1 - 0.025 14.3 2.7 0.068 12.9 0.0 2.2 2 1 0 2 2 2 0 Cupin-like domain Cupin_6 PF12852.7 CBZ37901.1 - 0.031 14.0 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Cupin CDC45 PF02724.14 CBZ37901.1 - 0.11 10.8 7.1 0.11 10.7 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein 2OG-FeII_Oxy_5 PF13759.6 CBZ37901.1 - 0.19 12.1 0.7 0.52 10.8 0.0 2.0 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Cupin_1 PF00190.22 CBZ37901.1 - 0.22 11.1 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 Cupin Presenilin PF01080.17 CBZ37901.1 - 0.24 10.1 3.0 0.25 10.1 3.0 1.2 1 0 0 1 1 1 0 Presenilin AAA_17 PF13207.6 CBZ37901.1 - 0.73 10.3 10.0 5.2 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain cNMP_binding PF00027.29 CBZ37903.1 - 2.2e-09 37.3 0.0 5.1e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain adh_short PF00106.25 CBZ37904.1 - 5.1e-13 48.9 1.3 1.6e-12 47.3 1.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ37904.1 - 4.3e-07 29.7 3.1 1.1e-06 28.4 3.1 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CBZ37904.1 - 0.016 14.7 0.2 0.032 13.7 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Proteasome PF00227.26 CBZ37905.1 - 3.7e-06 26.6 0.0 3.7e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TPT PF03151.16 CBZ37907.1 - 3.4e-08 33.2 25.4 4.2e-08 32.9 25.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CBZ37907.1 - 0.0011 19.2 40.6 0.014 15.6 18.0 2.1 2 0 0 2 2 2 2 EamA-like transporter family AAA_33 PF13671.6 CBZ37908.1 - 3.5e-13 49.9 0.0 5.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ37908.1 - 0.0019 18.5 0.1 0.018 15.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBZ37908.1 - 0.0055 16.7 0.0 0.0086 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) KTI12 PF08433.10 CBZ37908.1 - 0.008 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 CopD PF05425.13 CBZ37908.1 - 0.012 16.0 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Copper resistance protein D AAA_14 PF13173.6 CBZ37908.1 - 0.017 15.1 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBZ37908.1 - 0.018 14.3 0.0 0.028 13.7 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin Ctr PF04145.15 CBZ37908.1 - 0.049 14.3 0.0 0.065 13.9 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Bacteriocin_IId PF09221.10 CBZ37909.1 - 0.0036 17.5 0.1 0.011 15.9 0.1 1.9 1 0 0 1 1 1 1 Bacteriocin class IId cyclical uberolysin-like PIP5K PF01504.18 CBZ37910.1 - 4.1e-72 242.7 0.0 6.8e-72 242.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Sec15 PF04091.12 CBZ37910.1 - 0.043 13.2 0.1 0.081 12.3 0.1 1.3 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like DNA_pol_A_exo1 PF01612.20 CBZ37911.1 - 7.7e-40 136.5 0.6 1.3e-39 135.7 0.6 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CBZ37911.1 - 1.1e-18 67.7 0.1 6e-18 65.3 0.1 2.3 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 CBZ37911.1 - 4.7e-09 36.1 0.0 1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Pup PF05639.11 CBZ37911.1 - 3.4 8.6 4.6 3.2 8.7 0.0 2.6 2 0 0 2 2 2 0 Pup-like protein Amastin PF07344.11 CBZ37912.1 - 4.7e-54 182.4 4.7 5.6e-54 182.2 4.7 1.0 1 0 0 1 1 1 1 Amastin surface glycoprotein SUR7 PF06687.12 CBZ37912.1 - 0.0035 17.0 6.8 0.025 14.2 0.9 2.9 3 0 0 3 3 3 2 SUR7/PalI family Adeno_E3_14_5 PF04834.12 CBZ37912.1 - 0.24 12.0 1.3 0.36 11.4 0.1 1.9 2 0 0 2 2 2 0 Early E3 14.5 kDa protein DUF2721 PF11026.8 CBZ37912.1 - 0.34 10.8 4.9 0.27 11.1 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) 2-Hacid_dh_C PF02826.19 CBZ37913.1 - 1.1e-38 132.4 0.0 1.5e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CBZ37913.1 - 5.8e-06 26.6 0.2 1.9e-05 24.9 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CBZ37913.1 - 0.00015 21.4 0.1 0.00028 20.5 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 CBZ37913.1 - 0.0011 19.5 0.1 0.0044 17.6 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 CBZ37913.1 - 0.0013 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 CBZ37913.1 - 0.0058 16.7 2.5 0.0067 16.5 0.2 2.2 3 1 0 3 3 3 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh PF00389.30 CBZ37913.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Sacchrp_dh_NADP PF03435.18 CBZ37913.1 - 0.2 11.9 1.9 1.1 9.6 0.7 2.6 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PK PF00224.21 CBZ37914.1 - 2e-20 73.0 0.1 2.2e-20 72.9 0.1 1.0 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PI-PLC-X PF00388.19 CBZ37915.1 - 4.9e-58 194.8 0.0 8.4e-58 194.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CBZ37915.1 - 4.6e-33 114.0 0.1 1.8e-32 112.0 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_1 PF00036.32 CBZ37915.1 - 0.0018 17.7 0.3 0.0056 16.1 0.3 1.9 1 0 0 1 1 1 1 EF hand C2 PF00168.30 CBZ37915.1 - 0.0043 17.3 0.0 0.0088 16.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 CBZ37915.1 - 0.014 15.8 5.0 0.063 13.7 0.5 1.8 1 1 1 2 2 2 0 EF-hand domain pair Transket_pyr PF02779.24 CBZ37916.1 - 2.3e-40 138.2 0.0 3.9e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CBZ37916.1 - 1.4e-35 121.8 0.0 3.4e-35 120.6 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CBZ37916.1 - 7e-06 26.3 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II SRP14 PF02290.15 CBZ37917.1 - 1.7 9.1 5.2 5.1 7.5 0.5 2.7 2 0 0 2 2 2 0 Signal recognition particle 14kD protein Band_7 PF01145.25 CBZ37918.1 - 8.3e-25 87.8 3.5 1.4e-24 87.1 3.5 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Nfu_N PF08712.11 CBZ37918.1 - 0.16 12.0 0.1 0.42 10.7 0.0 1.7 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal TrkH PF02386.16 CBZ37919.1 - 1.1e-07 30.7 22.5 1.7e-07 30.1 2.7 3.5 3 1 1 4 4 4 3 Cation transport protein UCR_14kD PF02271.16 CBZ37921.1 - 5.6e-08 32.7 0.0 3.2e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Clat_adaptor_s PF01217.20 CBZ37922.1 - 5.7e-10 39.3 0.0 7.9e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L2 PF00181.23 CBZ37922.1 - 0.084 12.9 0.0 0.22 11.5 0.0 1.7 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain LMBR1 PF04791.16 CBZ37923.1 - 6.6e-19 68.2 22.9 2.7e-13 49.7 3.1 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein CTV_P33 PF07184.11 CBZ37923.1 - 0.021 13.9 0.0 0.71 8.9 0.0 2.2 2 0 0 2 2 2 0 Citrus tristeza virus P33 protein DUF1206 PF06724.11 CBZ37923.1 - 2.5 8.3 0.0 2.5 8.3 0.0 4.2 5 1 0 5 5 5 0 Domain of Unknown Function (DUF1206) Arf PF00025.21 CBZ37924.1 - 5.3e-65 218.1 0.1 6e-65 217.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CBZ37924.1 - 7.9e-13 48.3 1.7 1e-07 31.4 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CBZ37924.1 - 9.5e-12 45.2 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CBZ37924.1 - 1.4e-09 37.7 0.0 1.6e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CBZ37924.1 - 1.4e-08 34.4 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CBZ37924.1 - 2e-07 30.8 0.0 2.3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CBZ37924.1 - 9.3e-07 28.9 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CBZ37924.1 - 7e-05 22.5 0.0 0.00069 19.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CBZ37924.1 - 0.0015 18.1 0.1 0.0048 16.4 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 CBZ37924.1 - 0.0092 15.6 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Mito_carr PF00153.27 CBZ37926.1 - 3.8e-05 23.5 4.0 0.14 12.1 1.4 2.9 2 1 0 2 2 2 2 Mitochondrial carrier protein Tropomyosin_1 PF12718.7 CBZ37928.1 - 0.017 15.3 4.9 0.017 15.3 4.9 2.6 2 2 1 3 3 3 0 Tropomyosin like SKA2 PF16740.5 CBZ37929.1 - 0.0022 17.7 6.3 0.0022 17.7 6.3 8.3 2 2 8 10 10 10 1 Spindle and kinetochore-associated protein 2 GAS PF13851.6 CBZ37929.1 - 0.0076 15.6 7.0 0.0076 15.6 7.0 8.4 2 2 4 7 7 7 3 Growth-arrest specific micro-tubule binding YabA PF06156.13 CBZ37929.1 - 0.0089 16.6 6.2 0.0089 16.6 6.2 10.4 3 3 7 10 10 10 2 Initiation control protein YabA Spc7 PF08317.11 CBZ37929.1 - 0.04 12.8 125.0 0.024 13.5 14.0 7.3 2 2 5 7 7 7 0 Spc7 kinetochore protein BRICHOS PF04089.14 CBZ37929.1 - 0.045 14.0 0.8 0.44 10.8 0.1 3.2 2 0 0 2 2 2 0 BRICHOS domain WD40_alt PF14077.6 CBZ37929.1 - 3.1 7.7 13.9 0.8 9.6 1.0 5.2 6 0 0 6 6 6 0 Alternative WD40 repeat motif Glyco_tran_WbsX PF14307.6 CBZ37929.1 - 3.2 7.1 7.7 2.7 7.3 0.6 2.8 2 0 0 2 2 2 0 Glycosyltransferase WbsX Kisspeptin PF15152.6 CBZ37929.1 - 3.7 8.4 5.2 2.3 9.1 0.2 3.2 2 0 0 2 2 2 0 Kisspeptin SLATT_5 PF18160.1 CBZ37929.1 - 4.3 6.6 8.4 0.24 10.7 0.1 3.2 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 Strep_SA_rep PF06696.11 CBZ37929.1 - 5.8 7.0 8.0 17 5.5 0.1 3.6 3 0 0 3 3 3 0 Streptococcal surface antigen repeat NIF PF03031.18 CBZ37930.1 - 3.2e-32 111.5 0.0 4.5e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 CBZ37930.1 - 0.0002 21.7 0.0 0.00028 21.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CBZ37930.1 - 0.0012 19.3 0.0 0.0053 17.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.12 CBZ37930.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) ATG16 PF08614.11 CBZ37931.1 - 0.0021 18.3 8.9 0.0021 18.3 8.9 16.8 5 4 10 15 15 15 5 Autophagy protein 16 (ATG16) DUF1242 PF06842.12 CBZ37932.1 - 5.5e-10 38.9 1.5 8.2e-10 38.3 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DnaJ PF00226.31 CBZ37934.1 - 1.2e-05 25.4 0.0 2.8e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 DnaJ domain zf-CCCH PF00642.24 CBZ37934.1 - 0.0015 18.4 4.5 0.0037 17.2 4.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CBZ37934.1 - 0.0026 18.5 0.4 0.0073 17.0 0.4 1.7 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 CBZ37934.1 - 0.0081 16.2 3.8 0.0081 16.2 3.8 2.2 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBZ37934.1 - 1.3 8.9 8.5 0.2 11.5 2.7 2.2 2 0 0 2 2 2 0 CCCH-type zinc finger Ribosomal_L7Ae PF01248.26 CBZ37935.1 - 2.1e-24 85.1 0.0 2.3e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ArfGap PF01412.18 CBZ37937.1 - 3e-29 101.5 0.0 6.7e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF5323 PF17257.2 CBZ37937.1 - 0.59 10.0 2.3 0.54 10.2 0.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5323) CCSMST1 PF15013.6 CBZ37938.1 - 0.24 11.6 1.8 2.5 8.3 0.1 2.0 1 1 1 2 2 2 0 CCSMST1 family Nup96 PF12110.8 CBZ37941.1 - 0.029 13.5 0.0 0.065 12.3 0.0 1.6 2 0 0 2 2 2 0 Nuclear protein 96 MAD PF05557.13 CBZ37941.1 - 0.046 12.1 1.1 0.12 10.8 0.1 1.9 2 0 0 2 2 2 0 Mitotic checkpoint protein Ank_2 PF12796.7 CBZ37942.1 - 6.7e-09 36.2 0.0 1e-06 29.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CBZ37942.1 - 1.6e-07 31.1 0.1 0.041 14.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CBZ37942.1 - 1e-06 29.2 0.0 0.012 16.2 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ37942.1 - 0.001 19.4 0.2 0.17 12.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CBZ37942.1 - 0.02 15.2 0.0 0.4 11.1 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeats (many copies) pPIWI_RE_Y PF18156.1 CBZ37942.1 - 0.14 12.6 0.5 0.34 11.3 0.0 1.9 2 0 0 2 2 2 0 pPIWI_RE three-gene island domain Y Aminotran_1_2 PF00155.21 CBZ37943.1 - 6e-49 167.1 0.0 7.1e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CBZ37943.1 - 0.043 12.8 0.0 0.073 12.0 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CBZ37943.1 - 0.06 12.7 0.0 0.63 9.3 0.0 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family adh_short PF00106.25 CBZ37944.1 - 3.3e-40 137.6 0.2 4.3e-40 137.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ37944.1 - 3.4e-25 89.0 1.0 4.4e-25 88.6 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ37944.1 - 2.4e-15 56.9 0.6 3.8e-15 56.3 0.6 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CBZ37944.1 - 0.0014 17.8 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 CBZ37944.1 - 0.083 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TGBp3 PF02495.17 CBZ37944.1 - 0.19 11.4 0.5 0.4 10.4 0.5 1.5 1 0 0 1 1 1 0 Triple gene block 3 ECH_1 PF00378.20 CBZ37947.1 - 5.1e-45 153.7 0.4 1.1e-44 152.6 0.4 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CBZ37947.1 - 1.8e-21 77.0 0.7 9.9e-20 71.3 0.1 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase T2SSF PF00482.23 CBZ37947.1 - 0.0045 16.9 0.2 0.0089 16.0 0.2 1.5 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F DEAD PF00270.29 CBZ37948.1 - 5.3e-45 153.3 0.4 7.7e-45 152.8 0.4 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ37948.1 - 1.6e-28 99.2 1.4 7.2e-28 97.2 0.9 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CBZ37948.1 - 0.00067 18.9 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 CBZ37948.1 - 0.0057 17.0 0.3 0.01 16.2 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CBZ37948.1 - 0.0059 16.9 0.3 0.018 15.3 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CBZ37948.1 - 0.11 12.9 0.8 1.9 8.9 0.8 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thioredoxin PF00085.20 CBZ37949.1 - 1.5e-05 24.9 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CBZ37949.1 - 8.6e-05 22.8 0.1 0.016 15.5 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CBZ37949.1 - 0.034 14.6 0.1 0.21 12.1 0.1 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CBZ37949.1 - 0.068 13.4 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 CBZ37949.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin PBP1_TM PF14812.6 CBZ37949.1 - 0.9 10.0 3.3 3.6 8.0 0.7 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_S3Ae PF01015.18 CBZ37951.1 - 1.3e-68 230.6 3.6 1.5e-68 230.4 3.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DNA_pol3_delt_C PF14840.6 CBZ37951.1 - 0.14 12.5 2.6 0.21 11.9 2.0 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term Ribosomal_S3Ae PF01015.18 CBZ37952.1 - 1.3e-68 230.6 3.6 1.5e-68 230.4 3.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DNA_pol3_delt_C PF14840.6 CBZ37952.1 - 0.14 12.5 2.6 0.21 11.9 2.0 1.5 1 1 0 1 1 1 0 Processivity clamp loader gamma complex DNA pol III C-term SHIPPO-rpt PF07004.12 CBZ37953.1 - 3.7e-14 52.9 18.7 0.12 13.3 0.0 8.5 8 0 0 8 8 8 7 Sperm-tail PG-rich repeat Arrestin_N PF00339.29 CBZ37954.1 - 1.3e-08 35.0 0.0 3.6e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.29 CBZ37955.1 - 4.1e-05 23.7 0.1 0.00015 21.8 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain dsrm PF00035.26 CBZ37955.1 - 4.1 8.2 0.0 4.1 8.2 0.0 2.8 3 0 0 3 3 3 0 Double-stranded RNA binding motif HAP2-GCS1 PF10699.9 CBZ37956.1 - 1.1e-19 70.1 0.0 2.5e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Male gamete fusion factor Shisa PF13908.6 CBZ37956.1 - 0.00076 19.8 0.0 0.0026 18.1 0.0 1.9 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3737 PF12541.8 CBZ37956.1 - 0.021 14.0 0.0 0.57 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3737) Pkinase PF00069.25 CBZ37959.1 - 1.3e-52 178.7 0.0 6e-33 114.3 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ37959.1 - 1.4e-24 86.8 0.1 1.7e-18 66.9 0.1 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase EF-hand_6 PF13405.6 CBZ37959.1 - 2.1e-07 30.3 0.0 0.0068 16.3 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CBZ37959.1 - 3.3e-07 30.7 0.2 0.014 15.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ37959.1 - 0.00028 20.2 0.0 0.15 11.7 0.0 3.1 3 0 0 3 3 3 2 EF hand Kinase-like PF14531.6 CBZ37959.1 - 0.0011 18.4 0.0 0.56 9.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CBZ37959.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_8 PF13855.6 CBZ37960.1 - 4e-05 23.3 6.9 0.098 12.4 3.3 2.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CBZ37960.1 - 0.0035 17.7 4.2 0.68 10.4 0.7 4.1 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) DUF3079 PF11278.8 CBZ37960.1 - 0.042 13.7 2.6 0.83 9.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) LRRNT_2 PF08263.12 CBZ37961.1 - 0.028 14.7 6.9 0.58 10.5 1.4 2.7 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 CBZ37961.1 - 0.035 14.6 1.9 0.58 10.7 0.2 3.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) PIP5K PF01504.18 CBZ37962.1 - 1.1e-58 198.7 0.0 3.2e-58 197.1 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF4763 PF15960.5 CBZ37962.1 - 0.052 12.9 2.4 0.084 12.2 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) WD40 PF00400.32 CBZ37963.1 - 3.5e-06 27.6 18.8 0.0011 19.7 1.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat Snf7 PF03357.21 CBZ37964.1 - 8.7e-39 132.9 18.9 1e-38 132.7 18.9 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 CBZ37964.1 - 0.0023 18.3 5.6 0.0027 18.1 0.7 2.6 1 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein XRN_M PF17846.1 CBZ37964.1 - 0.11 11.4 7.4 0.15 10.9 7.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF3573 PF12097.8 CBZ37964.1 - 0.27 10.0 3.7 0.36 9.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FlaC_arch PF05377.11 CBZ37964.1 - 0.72 10.3 4.6 10 6.6 0.6 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Phage_Gp23 PF10669.9 CBZ37964.1 - 7.7 6.9 11.0 0.73 10.2 4.8 2.0 1 1 1 2 2 2 0 Protein gp23 (Bacteriophage A118) Ribosomal_L18A PF01775.17 CBZ37966.1 - 5e-41 139.6 1.4 6.5e-41 139.2 1.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A HalX PF08663.10 CBZ37967.1 - 0.29 11.5 1.7 1.1 9.6 0.2 2.6 2 0 0 2 2 2 0 HalX domain Nup35_RRM_2 PF14605.6 CBZ37969.1 - 2.2e-15 56.4 0.0 3.4e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Glyco_hydro_32N PF00251.20 CBZ37970.1 - 2.3e-58 198.1 4.6 2.4e-57 194.8 4.1 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CBZ37970.1 - 6e-16 58.8 0.0 2.4e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_4 PF14295.6 CBZ37970.1 - 0.00036 20.4 1.6 0.0012 18.7 1.6 1.9 1 0 0 1 1 1 1 PAN domain Glyco_hydro_32N PF00251.20 CBZ37971.1 - 2.3e-58 198.1 4.6 2.4e-57 194.8 4.1 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CBZ37971.1 - 6e-16 58.8 0.0 2.4e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal PAN_4 PF14295.6 CBZ37971.1 - 0.00036 20.4 1.6 0.0012 18.7 1.6 1.9 1 0 0 1 1 1 1 PAN domain zf-C3HC4_2 PF13923.6 CBZ37973.1 - 0.0057 16.5 6.9 0.0057 16.5 6.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ37973.1 - 0.012 15.9 9.1 0.012 15.9 9.1 2.8 2 0 0 2 2 2 0 Ring finger domain zf-RING_6 PF14835.6 CBZ37973.1 - 0.12 12.3 9.7 0.013 15.3 4.7 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CBZ37973.1 - 0.71 9.8 12.9 0.32 10.9 8.0 2.8 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBZ37973.1 - 0.74 9.8 12.8 0.12 12.3 8.2 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CBZ37973.1 - 1.3 8.9 15.5 0.084 12.8 8.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CBZ37973.1 - 2.8 8.0 14.9 0.12 12.5 8.3 2.2 3 0 0 3 3 3 0 RING-type zinc-finger DUF1272 PF06906.11 CBZ37973.1 - 4.5 7.5 9.8 0.8 9.8 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DRIM PF07539.12 CBZ37974.1 - 5.8e-13 48.0 18.8 1.5e-10 40.1 0.1 5.4 5 0 0 5 5 5 3 Down-regulated in metastasis TPR_12 PF13424.6 CBZ37976.1 - 2.7e-59 197.4 39.0 4.7e-14 52.4 1.3 8.2 6 2 2 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ37976.1 - 3.2e-41 138.1 30.1 1.4e-06 28.0 0.3 11.7 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ37976.1 - 3.1e-21 73.7 40.1 0.0024 17.8 0.4 12.3 12 1 0 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ37976.1 - 1.2e-17 62.8 41.7 0.00014 21.5 0.0 12.0 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ37976.1 - 6e-17 60.4 35.4 0.044 14.0 0.0 12.4 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ37976.1 - 2.8e-15 55.1 22.8 0.00025 20.9 0.1 9.7 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ37976.1 - 3.7e-11 43.5 26.1 0.0074 16.9 0.1 8.2 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 CBZ37976.1 - 4.7e-08 32.8 14.5 0.00082 18.8 4.7 4.4 2 1 2 5 5 5 3 MalT-like TPR region TPR_14 PF13428.6 CBZ37976.1 - 6.7e-08 32.7 30.7 4.4 8.4 0.0 10.8 9 3 2 11 11 11 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ37976.1 - 8.3e-06 26.2 24.1 0.009 16.5 0.4 7.5 7 1 0 8 8 8 2 Tetratricopeptide repeat SET_assoc PF11767.8 CBZ37976.1 - 0.027 14.1 0.0 0.082 12.6 0.0 1.8 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated SHNi-TPR PF10516.9 CBZ37976.1 - 0.028 13.9 1.5 37 3.9 0.0 4.3 5 0 0 5 5 5 0 SHNi-TPR ANAPC5 PF12862.7 CBZ37976.1 - 0.15 12.2 15.1 4.3 7.5 0.2 6.0 4 2 2 6 6 6 0 Anaphase-promoting complex subunit 5 TPR_17 PF13431.6 CBZ37976.1 - 0.37 11.3 17.2 26 5.5 0.0 7.6 8 1 0 8 8 7 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ37976.1 - 0.78 10.0 34.9 0.55 10.5 3.2 7.6 4 4 3 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 CBZ37976.1 - 5.7 7.1 11.6 18 5.5 0.2 4.9 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain ATP-synt_D PF01813.17 CBZ37977.1 - 6.9e-75 251.2 0.8 9.6e-75 250.7 0.8 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Mit_ribos_Mrp51 PF11709.8 CBZ37977.1 - 0.016 14.8 0.2 0.021 14.4 0.2 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Exo_endo_phos PF03372.23 CBZ37978.1 - 5.5e-08 32.6 0.0 9.9e-08 31.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SET PF00856.28 CBZ37980.1 - 1.2e-11 45.3 0.6 6.4e-08 33.2 0.0 3.1 1 1 0 2 2 2 2 SET domain FHA PF00498.26 CBZ37981.1 - 0.053 13.9 0.0 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 FHA domain PA28_beta PF02252.18 CBZ37982.1 - 6.4e-10 38.9 0.1 1.8e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Proteasome activator pa28 beta subunit CBS PF00571.28 CBZ37983.1 - 3.3e-16 59.5 1.3 0.00017 21.9 0.0 4.3 4 0 0 4 4 4 4 CBS domain RrnaAD PF00398.20 CBZ37984.1 - 2e-25 89.4 0.0 1e-14 54.3 0.0 2.0 2 0 0 2 2 2 2 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 CBZ37984.1 - 0.0013 19.4 0.0 0.0033 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 CBZ37984.1 - 0.053 13.0 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF1054 PF06335.12 CBZ37984.1 - 0.15 12.0 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) Actin PF00022.19 CBZ37986.1 - 8.6e-58 195.9 0.0 2.5e-47 161.4 0.0 2.0 2 0 0 2 2 2 2 Actin ASFV_J13L PF05568.11 CBZ37987.1 - 0.0077 16.0 1.0 0.043 13.6 1.0 2.4 1 0 0 1 1 1 1 African swine fever virus J13L protein Aminotran_1_2 PF00155.21 CBZ37989.1 - 3.5e-67 227.1 0.0 4e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FYVE_2 PF02318.16 CBZ37989.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger FAD_binding_2 PF00890.24 CBZ37990.1 - 8.8e-83 278.7 0.1 1.4e-82 278.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.15 CBZ37990.1 - 1.9e-48 165.2 0.0 7.1e-48 163.4 0.0 1.8 1 1 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.21 CBZ37990.1 - 8e-18 65.1 0.0 1.6e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DAO PF01266.24 CBZ37990.1 - 7.4e-13 48.8 0.2 1.9e-12 47.5 0.2 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CBZ37990.1 - 1.3e-09 37.9 5.2 3.9e-09 36.4 4.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_6 PF00970.24 CBZ37990.1 - 4.6e-09 36.5 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Pyr_redox_2 PF07992.14 CBZ37990.1 - 2e-08 33.9 0.0 5.4e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ37990.1 - 5.4e-07 29.8 1.4 2.8e-06 27.5 1.4 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 CBZ37990.1 - 1.7e-06 27.5 0.5 4.1e-06 26.2 0.5 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CBZ37990.1 - 4.2e-06 26.1 5.7 1e-05 24.8 4.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 CBZ37990.1 - 0.00033 19.5 5.1 0.00076 18.3 3.1 2.3 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 CBZ37990.1 - 0.0048 17.4 0.9 0.012 16.1 0.9 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_6 PF08030.12 CBZ37990.1 - 0.0051 16.9 0.0 0.075 13.2 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox_3 PF13738.6 CBZ37990.1 - 0.0082 15.4 0.9 0.076 12.3 0.7 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBZ37990.1 - 0.065 12.5 1.2 0.1 11.8 1.2 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CBZ37990.1 - 0.28 10.2 1.9 0.48 9.4 1.9 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein S_4TM PF18159.1 CBZ37991.1 - 1.4 8.1 8.2 1.6 8.0 0.1 3.1 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain DUF2838 PF10998.8 CBZ37992.1 - 1.3e-15 57.6 23.1 3.2e-10 40.2 5.2 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF2838) DUF2852 PF11014.8 CBZ37992.1 - 0.83 9.8 4.0 14 5.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) PBP1_TM PF14812.6 CBZ37993.1 - 3.5 8.1 5.7 0.67 10.4 1.9 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Telomere_reg-2 PF10193.9 CBZ37994.1 - 0.015 15.7 0.0 0.058 13.8 0.0 2.1 1 0 0 1 1 1 0 Telomere length regulation protein DUF4399 PF14347.6 CBZ37994.1 - 0.17 12.2 0.0 0.52 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) BatA PF07584.11 CBZ37994.1 - 2.4 8.6 5.1 8.6 6.8 0.0 3.0 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal COX6B PF02297.17 CBZ37996.1 - 0.005 17.1 0.1 0.28 11.4 0.0 2.3 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb UPF0203 PF05254.12 CBZ37996.1 - 0.024 14.9 0.4 0.12 12.6 0.4 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) GP120 PF00516.18 CBZ37996.1 - 0.055 12.1 0.0 0.062 11.9 0.0 1.1 1 0 0 1 1 1 0 Envelope glycoprotein GP120 CX9C PF16860.5 CBZ37996.1 - 0.38 10.8 3.3 0.34 10.9 0.4 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF2065 PF09838.9 CBZ37999.1 - 0.0053 16.7 1.1 0.027 14.5 0.2 2.8 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2065) HemY_N PF07219.13 CBZ37999.1 - 0.061 13.5 3.6 0.18 12.0 0.6 3.2 2 0 0 2 2 2 0 HemY protein N-terminus tRNA_bind_3 PF17176.4 CBZ37999.1 - 0.073 13.4 0.4 0.31 11.3 0.4 2.1 1 0 0 1 1 1 0 tRNA-binding domain ECH_2 PF16113.5 CBZ38000.1 - 0.05 13.1 0.7 0.064 12.8 0.7 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Mrpl_C PF18502.1 CBZ38000.1 - 0.13 12.5 1.2 0.19 12.0 1.2 1.2 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain DUF4355 PF14265.6 CBZ38000.1 - 5.7 7.2 9.9 1.4 9.1 5.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) DUF4131 PF13567.6 CBZ38001.1 - 0.11 12.2 0.2 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) PSP1 PF04468.12 CBZ38002.1 - 4e-23 81.5 0.3 8.7e-23 80.4 0.3 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Cupin_8 PF13621.6 CBZ38003.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Cupin-like domain Aldose_epim PF01263.20 CBZ38004.1 - 4e-36 124.9 0.0 4.6e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF362 PF04015.12 CBZ38004.1 - 0.09 13.0 0.0 0.25 11.6 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF362) Pkinase PF00069.25 CBZ38007.1 - 3.1e-24 85.8 0.0 3.8e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38007.1 - 3.4e-12 46.2 0.0 3.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ38007.1 - 1.9e-10 40.1 0.5 2.6e-10 39.6 0.5 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ38007.1 - 6.5e-06 26.2 0.1 0.0016 18.4 0.2 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family polyprenyl_synt PF00348.17 CBZ38007.1 - 0.0021 17.1 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.25 CBZ38008.1 - 1.2e-24 87.1 0.0 1.9e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38008.1 - 4.5e-13 49.1 0.0 5.6e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ38008.1 - 9.9e-09 34.5 0.0 1.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ38008.1 - 0.0001 22.4 0.0 0.00024 21.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CBZ38008.1 - 0.008 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH PF00642.24 CBZ38009.1 - 8.5e-06 25.6 6.4 1.3e-05 24.9 6.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cupin_5 PF06172.11 CBZ38010.1 - 4e-44 150.2 0.0 5e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) zf-CCCH PF00642.24 CBZ38011.1 - 5.3e-07 29.4 1.0 1.1e-06 28.4 1.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ38011.1 - 0.00035 20.5 0.8 0.00072 19.5 0.8 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ38011.1 - 0.022 15.2 0.6 0.044 14.3 0.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CBZ38011.1 - 0.074 12.9 1.2 0.17 11.8 1.2 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger Membralin PF09746.9 CBZ38011.1 - 0.15 11.1 2.0 0.25 10.4 2.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein Pkinase PF00069.25 CBZ38012.1 - 1.2e-61 208.4 0.0 2.1e-61 207.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38012.1 - 1e-21 77.4 0.0 2.2e-21 76.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ38012.1 - 4.8e-05 22.8 0.1 0.071 12.4 0.2 3.1 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 CBZ38012.1 - 0.002 17.5 0.1 0.0038 16.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CBZ38012.1 - 0.028 13.2 0.0 0.049 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 CBZ38012.1 - 0.065 12.9 0.1 0.5 10.0 0.1 2.2 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 QWRF PF04484.12 CBZ38012.1 - 0.12 12.1 2.6 0.19 11.5 2.6 1.2 1 0 0 1 1 1 0 QWRF family DUF1645 PF07816.11 CBZ38012.1 - 0.18 12.4 4.9 0.33 11.5 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) YL1 PF05764.13 CBZ38014.1 - 0.00018 21.7 0.8 0.00025 21.3 0.8 1.1 1 0 0 1 1 1 1 YL1 nuclear protein eIF3_subunit PF08597.10 CBZ38014.1 - 0.0051 16.8 2.6 0.0077 16.2 2.6 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CDC45 PF02724.14 CBZ38014.1 - 0.024 12.9 3.2 0.034 12.4 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 CBZ38014.1 - 0.037 13.4 2.5 0.056 12.8 2.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) UPF0254 PF06787.11 CBZ38014.1 - 0.19 11.5 0.1 0.35 10.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Pox_RNA_Pol_19 PF05320.12 CBZ38014.1 - 0.21 11.6 0.5 0.33 10.9 0.5 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Rrn6 PF10214.9 CBZ38014.1 - 0.5 8.8 4.8 0.73 8.2 4.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Kri1 PF05178.12 CBZ38015.1 - 1.5e-20 73.6 9.8 1.5e-20 73.6 9.8 4.2 5 1 0 5 5 5 1 KRI1-like family Kri1_C PF12936.7 CBZ38015.1 - 4.6e-18 65.2 0.0 4.6e-18 65.2 0.0 2.4 2 0 0 2 2 2 1 KRI1-like family C-terminal Peptidase_M15_3 PF08291.11 CBZ38016.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Peptidase M15 Rdx PF10262.9 CBZ38017.1 - 4.2e-05 23.7 0.0 8.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Rdx family DUF3328 PF11807.8 CBZ38018.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) Hydin_ADK PF17213.3 CBZ38018.1 - 0.64 10.3 5.8 0.92 9.8 5.8 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain STT3 PF02516.14 CBZ38019.1 - 1.7e-19 70.1 3.2 2.3e-19 69.7 3.2 1.1 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit STT3 PF02516.14 CBZ38020.1 - 1.1e-39 136.7 21.8 1.2e-39 136.6 21.8 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT PF02366.18 CBZ38020.1 - 2.8e-06 27.1 10.4 5.5e-06 26.1 10.4 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF5379 PF17350.2 CBZ38020.1 - 0.077 13.3 0.8 0.077 13.3 0.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5379) DUF2929 PF11151.8 CBZ38020.1 - 0.12 12.7 0.5 0.12 12.7 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) Mannosyl_trans4 PF15971.5 CBZ38020.1 - 0.2 11.5 7.8 0.32 10.8 7.8 1.3 1 0 0 1 1 1 0 DolP-mannose mannosyltransferase STT3 PF02516.14 CBZ38021.1 - 7.2e-47 160.4 21.8 1.2e-46 159.7 21.8 1.4 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Mannosyl_trans4 PF15971.5 CBZ38021.1 - 2.3 8.0 14.6 0.59 10.0 7.3 2.8 2 0 0 2 2 2 0 DolP-mannose mannosyltransferase STT3 PF02516.14 CBZ38022.1 - 2.9e-19 69.4 4.5 3.4e-19 69.1 4.3 1.2 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Rhodanese PF00581.20 CBZ38023.1 - 3.3e-09 37.2 0.0 1.2e-08 35.4 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain FAD_binding_2 PF00890.24 CBZ38024.1 - 4.5e-84 283.0 0.1 6.7e-84 282.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbE PF02424.15 CBZ38024.1 - 4.1e-57 193.7 0.0 6.5e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 ApbE family NAD_binding_1 PF00175.21 CBZ38024.1 - 1.9e-18 67.1 0.0 4.8e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DAO PF01266.24 CBZ38024.1 - 3e-11 43.5 3.1 3.1e-10 40.2 3.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CBZ38024.1 - 2.9e-10 40.1 3.7 7.3e-10 38.8 3.7 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBZ38024.1 - 5.7e-09 35.6 0.5 2.3e-08 33.6 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ38024.1 - 1.2e-07 31.9 0.9 7.7e-07 29.3 0.7 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_6 PF00970.24 CBZ38024.1 - 1.4e-07 31.8 0.0 3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain GIDA PF01134.22 CBZ38024.1 - 2.8e-07 30.0 6.1 1.9e-06 27.3 2.1 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CBZ38024.1 - 1.8e-06 27.4 0.8 4.1e-06 26.2 0.8 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_6 PF08030.12 CBZ38024.1 - 2.4e-06 27.7 0.0 0.0029 17.8 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain HI0933_like PF03486.14 CBZ38024.1 - 2.9e-05 23.0 4.9 0.00013 20.8 1.7 2.6 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 CBZ38024.1 - 4.8e-05 23.8 1.5 0.00028 21.4 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CBZ38024.1 - 0.0006 19.2 0.3 0.022 14.0 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBZ38024.1 - 0.0017 17.7 0.4 0.0028 17.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CBZ38024.1 - 0.01 14.9 2.7 0.034 13.2 1.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.17 CBZ38024.1 - 0.024 13.9 1.5 0.097 11.9 0.4 2.5 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 CBZ38025.1 - 4.6e-90 302.7 0.6 5.3e-90 302.5 0.6 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CBZ38025.1 - 2.2e-09 37.4 8.0 3.1e-08 33.6 7.7 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CBZ38025.1 - 2.4e-08 33.6 1.4 7.2e-08 32.0 1.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CBZ38025.1 - 6.8e-08 32.6 1.2 2.4e-07 30.9 1.1 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CBZ38025.1 - 1e-07 31.7 4.7 1.8e-07 30.9 4.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CBZ38025.1 - 0.0002 20.8 2.5 0.13 11.5 1.3 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CBZ38025.1 - 0.00028 19.7 6.7 0.0024 16.6 0.2 3.3 4 0 0 4 4 4 2 HI0933-like protein GIDA PF01134.22 CBZ38025.1 - 0.00063 18.9 12.7 0.0011 18.2 3.7 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CBZ38025.1 - 0.0083 15.4 0.6 0.015 14.6 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CBZ38025.1 - 0.025 13.7 1.3 2.2 7.2 0.6 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 CBZ38025.1 - 0.027 15.0 1.2 0.13 12.9 0.6 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CBZ38025.1 - 0.028 13.7 0.6 0.053 12.8 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 CBZ38025.1 - 0.077 13.3 0.4 3.5 7.9 0.2 2.5 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.17 CBZ38025.1 - 0.095 11.9 3.6 0.049 12.9 1.1 1.8 2 0 0 2 2 2 0 Thi4 family HA2 PF04408.23 CBZ38026.1 - 7.6e-20 71.2 0.0 2e-19 69.8 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ38026.1 - 4.7e-16 59.1 0.0 1.3e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CBZ38026.1 - 4.5e-14 52.6 0.1 1e-13 51.4 0.1 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 CBZ38026.1 - 2.4e-07 31.1 0.0 6.9e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CBZ38026.1 - 4.5e-07 29.8 0.2 1.3e-06 28.3 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CBZ38026.1 - 0.00033 21.0 0.0 0.00071 19.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CBZ38026.1 - 0.00052 19.6 0.0 0.0016 18.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 CBZ38026.1 - 0.0025 16.9 0.0 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 CBZ38026.1 - 0.0058 16.6 0.0 0.31 11.0 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CBZ38026.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CBZ38026.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBZ38026.1 - 0.023 15.2 0.1 0.14 12.7 0.1 2.2 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 CBZ38026.1 - 0.04 13.6 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CBZ38026.1 - 0.11 12.9 0.1 0.44 10.9 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 CBZ38026.1 - 0.15 11.7 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Armet PF10208.9 CBZ38027.1 - 8.4e-09 35.5 0.0 2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding SAP PF02037.27 CBZ38027.1 - 2.9e-05 23.7 0.1 0.00011 21.8 0.0 2.0 2 0 0 2 2 2 1 SAP domain adh_short PF00106.25 CBZ38028.1 - 7.1e-46 156.1 3.3 8.4e-46 155.9 3.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ38028.1 - 1.3e-33 116.5 2.9 1.7e-33 116.1 2.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ38028.1 - 1.2e-11 44.9 0.2 1.5e-11 44.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ38028.1 - 0.00022 20.8 0.4 0.00035 20.1 0.4 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CBZ38028.1 - 0.03 13.5 1.3 0.045 12.9 1.3 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein SLBB PF10531.9 CBZ38028.1 - 0.086 12.7 0.0 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 SLBB domain DUF1161 PF06649.12 CBZ38028.1 - 0.77 10.0 5.2 4.9 7.4 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) adh_short PF00106.25 CBZ38029.1 - 6.1e-36 123.7 0.0 1.6e-35 122.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ38029.1 - 7e-20 71.6 0.0 2.2e-19 69.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ38029.1 - 7.7e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CBZ38029.1 - 0.00037 20.0 0.0 0.00063 19.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 CBZ38029.1 - 0.052 13.4 0.1 0.075 12.8 0.1 1.4 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Lambda_tail_I PF06805.12 CBZ38030.1 - 0.064 13.6 0.8 1.5 9.2 0.0 3.6 2 1 1 3 3 3 0 Bacteriophage lambda tail assembly protein I HrcA_DNA-bdg PF03444.15 CBZ38030.1 - 0.23 11.1 1.4 14 5.4 0.2 3.4 3 0 0 3 3 3 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DUF496 PF04363.12 CBZ38030.1 - 3.8 7.6 8.0 0.44 10.6 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF496) Fib_alpha PF08702.10 CBZ38030.1 - 7.7 6.7 42.1 0.55 10.4 1.8 6.7 3 3 5 8 8 8 0 Fibrinogen alpha/beta chain family Glutaredoxin PF00462.24 CBZ38031.1 - 3e-16 59.4 1.4 3.8e-12 46.2 0.1 3.2 2 1 1 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 CBZ38031.1 - 2.2e-12 46.9 0.0 5.7e-12 45.5 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 CBZ38031.1 - 0.00081 19.5 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CBZ38031.1 - 0.002 17.5 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CBZ38031.1 - 0.018 15.4 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.16 CBZ38031.1 - 0.05 12.5 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosducin AhpC-TSA PF00578.21 CBZ38031.1 - 0.092 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family AAA PF00004.29 CBZ38032.1 - 7.1e-36 123.6 0.0 1.7e-35 122.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ38032.1 - 8.2e-08 32.3 0.0 2e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 CBZ38032.1 - 1.8e-07 30.8 0.0 4.9e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CBZ38032.1 - 4.3e-07 29.8 0.0 1.5e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ38032.1 - 7.5e-07 29.7 0.2 2.2e-05 24.9 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 CBZ38032.1 - 2.2e-06 27.1 0.0 1.2e-05 24.7 0.0 2.1 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 CBZ38032.1 - 8.8e-06 26.0 0.1 0.0014 18.9 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ38032.1 - 1.3e-05 25.4 0.0 2.4e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ38032.1 - 4.9e-05 23.9 0.0 9.5e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBZ38032.1 - 0.00018 21.3 0.0 0.00036 20.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 CBZ38032.1 - 0.00045 20.6 0.0 0.00092 19.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.12 CBZ38032.1 - 0.0011 18.3 0.0 0.0061 15.9 0.0 2.2 3 0 0 3 3 3 1 Zeta toxin TsaE PF02367.17 CBZ38032.1 - 0.0017 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CBZ38032.1 - 0.0018 18.3 0.0 0.0035 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBZ38032.1 - 0.0025 17.5 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CBZ38032.1 - 0.0027 18.0 0.2 0.0083 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 CBZ38032.1 - 0.0029 17.7 0.0 0.017 15.3 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Mg_chelatase PF01078.21 CBZ38032.1 - 0.0031 16.9 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CBZ38032.1 - 0.0045 16.5 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 CBZ38032.1 - 0.0057 16.5 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CBZ38032.1 - 0.01 16.0 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 CBZ38032.1 - 0.011 15.5 0.0 0.038 13.7 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 CBZ38032.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 CBZ38032.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.6 1 1 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.17 CBZ38032.1 - 0.02 14.0 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Cytidylate_kin PF02224.18 CBZ38032.1 - 0.024 14.4 0.1 0.082 12.6 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase Sigma54_activ_2 PF14532.6 CBZ38032.1 - 0.026 14.7 0.0 0.062 13.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 CBZ38032.1 - 0.03 14.0 0.0 0.081 12.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 CBZ38032.1 - 0.034 13.3 0.0 0.097 11.8 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 CBZ38032.1 - 0.046 13.3 0.3 0.14 11.7 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 CBZ38032.1 - 0.053 13.9 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CBZ38032.1 - 0.054 13.3 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBZ38032.1 - 0.074 13.6 0.1 1.6 9.3 0.0 2.4 1 1 1 2 2 2 0 ABC transporter AAA_6 PF12774.7 CBZ38032.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 CBZ38032.1 - 0.075 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein PPV_E1_C PF00519.17 CBZ38032.1 - 0.085 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase DUF2075 PF09848.9 CBZ38032.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 CBZ38032.1 - 0.18 11.9 0.1 1.9 8.6 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase 2OG-FeII_Oxy_2 PF13532.6 CBZ38034.1 - 4e-08 33.7 0.0 5.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CBZ38034.1 - 0.013 15.9 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.26 CBZ38036.1 - 1.8e-54 183.2 0.0 2e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CBZ38036.1 - 0.0062 16.8 0.0 0.0072 16.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CBZ38036.1 - 0.14 11.9 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B CENP-T_C PF15511.6 CBZ38037.1 - 4.6e-06 26.7 0.1 6.9e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBZ38037.1 - 0.00071 19.8 0.1 0.00071 19.8 0.1 1.4 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CBZ38037.1 - 0.00072 19.7 0.1 0.0011 19.1 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CBZ38037.1 - 0.0016 18.4 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ38037.1 - 0.011 16.1 2.4 0.021 15.2 2.4 1.5 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ38037.1 - 0.033 14.3 0.0 0.043 13.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_S17e PF00833.18 CBZ38037.1 - 0.054 13.4 0.8 0.064 13.2 0.8 1.1 1 0 0 1 1 1 0 Ribosomal S17 Ly-6_related PF06579.12 CBZ38037.1 - 0.076 13.3 0.6 0.094 13.0 0.6 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein PCP_red PF08369.10 CBZ38037.1 - 0.15 12.3 1.6 0.26 11.5 0.3 2.1 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit DUF4400 PF14348.6 CBZ38037.1 - 0.17 11.3 0.1 0.26 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Thioredoxin PF00085.20 CBZ38039.1 - 1.8e-14 53.5 0.1 7.1e-14 51.7 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CBZ38039.1 - 0.0011 19.4 0.7 0.019 15.4 0.2 2.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 CBZ38039.1 - 0.0037 17.3 0.0 5.7 7.1 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_8 PF13905.6 CBZ38039.1 - 0.05 13.9 0.1 0.44 10.9 0.1 2.7 2 1 0 2 2 2 0 Thioredoxin-like OST3_OST6 PF04756.13 CBZ38039.1 - 0.1 12.0 0.5 0.36 10.1 0.1 2.0 2 1 0 2 2 2 0 OST3 / OST6 family, transporter family zf-CDGSH PF09360.10 CBZ38043.1 - 4.5e-19 68.4 6.9 1.1e-09 38.3 0.6 2.2 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Imm43 PF15570.6 CBZ38043.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 1 1 2 2 2 0 Immunity protein 43 DUF4379 PF14311.6 CBZ38043.1 - 0.11 12.9 2.4 1.6 9.2 0.1 2.5 2 1 0 2 2 2 0 Probable Zinc-ribbon domain Peptidase_M16 PF00675.20 CBZ38044.1 - 5.5e-27 94.6 0.0 9.3e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CBZ38044.1 - 2.6e-14 53.7 0.0 9.9e-14 51.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain DAHP_snth_FXD PF18152.1 CBZ38044.1 - 0.17 11.7 1.2 3.6 7.5 0.1 2.6 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain OTU PF02338.19 CBZ38045.1 - 1.2e-16 61.3 0.0 2.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-RanBP PF00641.18 CBZ38045.1 - 8.2e-06 25.0 1.6 8.2e-06 25.0 1.6 5.1 4 1 1 5 5 5 2 Zn-finger in Ran binding protein and others Peptidase_C65 PF10275.9 CBZ38045.1 - 0.00013 21.5 0.0 0.1 12.0 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain zf-tcix PF14952.6 CBZ38045.1 - 0.036 13.7 0.4 0.036 13.7 0.4 3.7 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding zf-ribbon_3 PF13248.6 CBZ38045.1 - 0.081 12.4 0.0 0.081 12.4 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain RecR PF02132.15 CBZ38045.1 - 0.3 10.7 16.4 3.8 7.2 0.4 4.4 4 1 0 4 4 4 0 RecR protein DZR PF12773.7 CBZ38045.1 - 2.7 8.1 31.0 0.93 9.6 6.7 4.1 3 1 0 3 3 3 0 Double zinc ribbon RRM_1 PF00076.22 CBZ38046.1 - 1.3e-06 28.1 0.0 0.059 13.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP-alpha_N PF04086.13 CBZ38046.1 - 0.092 12.7 9.9 0.12 12.3 9.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hid1 PF12722.7 CBZ38046.1 - 0.5 8.4 5.4 0.57 8.2 5.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein tRNA-synt_2b PF00587.25 CBZ38047.1 - 1e-30 107.0 0.0 1.6e-27 96.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CBZ38047.1 - 7.7e-17 61.2 0.2 1.6e-16 60.3 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 CBZ38047.1 - 2.7e-13 49.7 0.0 8.9e-13 48.1 0.0 1.9 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.14 CBZ38047.1 - 2.1e-11 43.7 0.0 3.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RraB PF06877.11 CBZ38047.1 - 0.015 16.0 0.4 0.24 12.2 0.0 2.7 2 0 0 2 2 2 0 Regulator of ribonuclease activity B TPR_1 PF00515.28 CBZ38048.1 - 1e-22 78.9 5.0 1.8e-06 27.5 0.1 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38048.1 - 7e-21 73.6 3.2 1.3e-05 24.8 0.7 5.5 3 2 2 5 5 5 3 TPR repeat TPR_2 PF07719.17 CBZ38048.1 - 1.8e-20 71.4 7.4 3.1e-05 23.8 0.0 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ38048.1 - 1.4e-18 65.8 6.1 8.2e-05 22.7 0.8 5.3 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ38048.1 - 3.3e-17 62.8 5.4 1.3e-08 35.3 0.1 4.9 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38048.1 - 4.2e-15 55.2 18.0 4e-05 24.1 0.0 7.5 4 2 4 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ38048.1 - 1.5e-12 46.7 4.6 0.0039 17.3 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ38048.1 - 2.5e-12 47.1 16.0 5.7e-06 26.7 0.2 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ38048.1 - 2.6e-08 33.3 1.5 0.53 10.4 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38048.1 - 4.2e-08 33.4 1.1 4.3e-05 23.7 0.0 4.4 3 1 2 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ38048.1 - 2.7e-06 27.4 1.8 0.15 12.3 0.1 3.7 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ38048.1 - 0.005 16.7 14.7 2 8.4 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ38048.1 - 0.0058 17.2 15.6 1 10.2 0.0 7.0 9 0 0 9 9 7 1 Tetratricopeptide repeat DUF5588 PF17826.1 CBZ38048.1 - 0.0099 14.8 1.9 0.63 8.9 0.0 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5588) TPR_20 PF14561.6 CBZ38048.1 - 0.011 16.1 15.6 1.5 9.2 0.1 5.3 3 1 2 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ38048.1 - 0.035 14.3 2.5 0.23 11.7 0.1 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 CBZ38048.1 - 0.18 11.9 3.7 4.5 7.4 0.1 4.3 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 CBZ38048.1 - 1.2 9.6 10.8 1.4 9.3 0.1 3.8 3 1 1 4 4 4 0 Bacterial transcriptional activator domain Ribosomal_L2 PF00181.23 CBZ38049.1 - 1.2e-13 50.8 0.0 1.5e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L2 PF00181.23 CBZ38050.1 - 9.5e-14 51.1 0.0 1.2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Choline_kinase PF01633.20 CBZ38053.1 - 1.9e-31 109.3 0.1 1.1e-30 106.8 0.1 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CBZ38053.1 - 5.9e-11 42.7 0.0 2.3e-08 34.3 0.0 2.7 2 1 0 2 2 2 2 Phosphotransferase enzyme family Arginase PF00491.21 CBZ38054.1 - 4.4e-75 252.8 0.0 5.2e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family NIF PF03031.18 CBZ38056.1 - 7.7e-18 64.7 0.0 1.5e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase zf-CCCH PF00642.24 CBZ38056.1 - 1.4e-06 28.1 1.2 2.8e-06 27.1 1.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CBZ38056.1 - 0.00019 21.3 0.2 0.00041 20.3 0.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CBZ38056.1 - 0.094 12.5 2.3 0.18 11.6 2.3 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger BRK PF07533.16 CBZ38056.1 - 0.1 12.3 0.0 17 5.2 0.0 2.5 2 0 0 2 2 2 0 BRK domain Myosin_N PF02736.19 CBZ38056.1 - 0.19 11.6 0.9 0.36 10.7 0.9 1.4 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Rieske PF00355.26 CBZ38059.1 - 2.6e-12 46.5 0.0 4.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Myb_DNA-bind_5 PF13873.6 CBZ38060.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Methyltransf_23 PF13489.6 CBZ38062.1 - 8.8e-20 71.2 0.0 1.7e-19 70.3 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ38062.1 - 1.2e-12 48.3 0.0 2.5e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ38062.1 - 3.8e-11 43.5 0.0 7.7e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ38062.1 - 2.1e-09 37.1 0.0 2.8e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CBZ38062.1 - 1.1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ38062.1 - 1.2e-07 32.3 0.0 5e-07 30.4 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain AsnC_trans_reg PF01037.21 CBZ38062.1 - 0.025 14.5 0.1 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain MTS PF05175.14 CBZ38062.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Peptidase_C14 PF00656.22 CBZ38063.1 - 3.6e-48 164.7 0.0 4.7e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain HrpB7 PF09486.10 CBZ38064.1 - 0.0002 21.8 8.0 0.0004 20.8 8.0 1.5 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Myosin_tail_1 PF01576.19 CBZ38064.1 - 0.023 12.5 7.2 0.035 11.9 7.2 1.1 1 0 0 1 1 1 0 Myosin tail Spc7 PF08317.11 CBZ38064.1 - 0.21 10.4 6.9 0.45 9.4 6.9 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 CBZ38064.1 - 0.38 10.8 2.5 0.5 10.4 1.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Nucleopor_Nup85 PF07575.13 CBZ38065.1 - 0.029 12.9 0.1 0.049 12.2 0.1 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin Laminin_G_3 PF13385.6 CBZ38067.1 - 7.7e-11 42.4 0.1 3e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF2972 PF11186.8 CBZ38067.1 - 0.11 12.3 1.5 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2972) EF-hand_7 PF13499.6 CBZ38068.1 - 4.1e-05 23.9 0.0 0.0002 21.7 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ38068.1 - 0.009 15.5 0.0 4.5 7.0 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CBZ38068.1 - 0.082 12.9 0.0 9.6 6.4 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain NYD-SP28_assoc PF14775.6 CBZ38070.1 - 0.1 12.7 0.2 0.1 12.7 0.2 5.6 5 1 1 6 6 6 0 Sperm tail C-terminal domain MutL_C PF08676.11 CBZ38071.1 - 3.8e-29 101.4 0.0 8.2e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CBZ38071.1 - 6.3e-10 38.8 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CBZ38071.1 - 5.9e-08 32.6 0.6 3.8e-07 30.0 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CBZ38071.1 - 0.00016 22.1 0.0 0.00053 20.5 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LRR_4 PF12799.7 CBZ38073.1 - 9.6e-10 38.6 4.6 0.00064 20.1 0.1 3.4 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ38073.1 - 7.9e-09 35.1 8.3 0.00026 20.7 4.7 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 CBZ38073.1 - 1.3e-05 24.8 2.9 2.2 8.6 0.5 5.0 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 CBZ38073.1 - 0.00019 21.5 5.0 6.6 7.7 0.0 5.1 4 1 0 4 4 4 1 Leucine Rich Repeat FlaC_arch PF05377.11 CBZ38073.1 - 0.011 16.0 1.6 0.041 14.3 0.3 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Spc29 PF17082.5 CBZ38073.1 - 0.014 15.2 1.7 0.014 15.2 1.7 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 KLRAQ PF10205.9 CBZ38073.1 - 0.018 15.3 3.3 0.018 15.3 3.3 2.2 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4685 PF15737.5 CBZ38073.1 - 0.33 11.4 0.1 0.33 11.4 0.1 3.7 2 1 2 4 4 4 0 Domain of unknown function (DUF4685) Macoilin PF09726.9 CBZ38073.1 - 0.44 9.1 14.0 0.56 8.7 14.0 1.1 1 0 0 1 1 1 0 Macoilin family GIT_CC PF16559.5 CBZ38073.1 - 1.7 8.5 12.5 0.11 12.3 1.3 3.7 4 0 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4200 PF13863.6 CBZ38073.1 - 9.3 6.7 12.9 0.39 11.1 6.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) RTC PF01137.21 CBZ38074.1 - 4.3e-42 143.8 0.1 4.9e-42 143.6 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CBZ38074.1 - 4.9e-27 94.4 0.1 7.9e-27 93.8 0.1 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Pro_isomerase PF00160.21 CBZ38075.1 - 3.8e-09 37.0 0.0 6.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD COX4_pro_2 PF07835.12 CBZ38075.1 - 0.19 11.9 0.3 0.36 11.0 0.3 1.4 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Pkinase PF00069.25 CBZ38076.1 - 1.2e-58 198.5 0.0 1.4e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38076.1 - 4.4e-18 65.5 0.0 7.8e-18 64.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ38076.1 - 2.2e-05 24.5 0.0 0.00084 19.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CBZ38076.1 - 0.04 13.2 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like UCH PF00443.29 CBZ38077.1 - 4.9e-49 167.1 0.3 8.7e-49 166.3 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ38077.1 - 5.2e-20 72.3 0.3 1.1e-17 64.7 0.2 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CBZ38077.1 - 2.6e-10 40.3 0.0 8.6e-10 38.7 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 CBZ38077.1 - 1e-09 38.1 0.0 2.7e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 Robl_LC7 PF03259.17 CBZ38078.1 - 6.6e-20 70.7 0.0 8.5e-20 70.3 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 CBZ38078.1 - 9.7e-07 28.6 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Epimerase_2 PF02350.19 CBZ38078.1 - 0.0018 17.2 0.2 0.0025 16.7 0.2 1.1 1 0 0 1 1 1 1 UDP-N-acetylglucosamine 2-epimerase SPOUT_MTase_2 PF14419.6 CBZ38078.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP CRM1_repeat_2 PF18784.1 CBZ38078.1 - 0.034 13.8 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 Glyco_hydro_38 PF18438.1 CBZ38078.1 - 0.063 13.3 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 Proteasom_Rpn13 PF04683.13 CBZ38080.1 - 5.5e-15 55.7 0.2 8.6e-15 55.1 0.2 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 CBZ38080.1 - 3.1e-10 40.2 0.0 5.3e-10 39.5 0.0 1.4 1 1 0 1 1 1 1 UCH-binding domain DUF737 PF05300.11 CBZ38081.1 - 0.0047 17.3 1.1 0.0049 17.2 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF737) RskA PF10099.9 CBZ38081.1 - 0.044 14.1 0.0 0.08 13.2 0.0 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA Pox_MCEL PF03291.16 CBZ38081.1 - 0.1 11.7 1.1 0.21 10.7 0.8 1.6 1 1 1 2 2 2 0 mRNA capping enzyme YabA PF06156.13 CBZ38081.1 - 1.1 9.9 10.6 0.12 13.0 2.6 2.2 1 1 0 2 2 2 0 Initiation control protein YabA DUF4570 PF15134.6 CBZ38081.1 - 3.1 7.8 9.6 0.34 10.9 2.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) DNA_pol_E_B PF04042.16 CBZ38082.1 - 9.5e-23 80.6 0.0 1.5e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DTW PF03942.15 CBZ38083.1 - 1.1e-22 80.7 0.1 1.9e-22 79.9 0.1 1.4 1 0 0 1 1 1 1 DTW domain C1_4 PF07975.12 CBZ38083.1 - 0.095 12.9 0.8 0.21 11.8 0.8 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain zinc_ribbon_9 PF14369.6 CBZ38083.1 - 1 9.6 4.8 4.6 7.6 0.4 2.5 1 1 1 2 2 2 0 zinc-ribbon GAS PF13851.6 CBZ38084.1 - 5.1e-58 195.7 26.3 5.1e-58 195.7 26.3 3.2 2 1 0 2 2 2 1 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 CBZ38084.1 - 0.099 12.9 13.4 1.3 9.3 0.5 4.5 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DinB_2 PF12867.7 CBZ38084.1 - 0.71 10.4 5.9 0.6 10.6 0.9 3.1 3 1 0 3 3 3 0 DinB superfamily Tyrosinase PF00264.20 CBZ38084.1 - 3.7 7.8 7.2 8.2 6.6 4.4 2.5 1 1 1 2 2 2 0 Common central domain of tyrosinase DUF5527 PF17665.1 CBZ38086.1 - 0.0025 17.3 0.4 0.0046 16.5 0.4 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF5527) EMP24_GP25L PF01105.24 CBZ38087.1 - 8.1e-40 136.7 0.1 9.6e-40 136.5 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MogR_DNAbind PF12181.8 CBZ38087.1 - 0.057 13.3 0.6 0.086 12.8 0.6 1.2 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) Pkinase PF00069.25 CBZ38088.1 - 7.4e-52 176.3 0.0 9.9e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38088.1 - 3.4e-21 75.7 0.0 5.9e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ38088.1 - 0.033 13.5 0.3 4.2 6.6 0.0 2.3 1 1 1 2 2 2 0 Kinase-like RIO1 PF01163.22 CBZ38088.1 - 0.13 11.8 0.1 0.28 10.8 0.1 1.4 1 1 0 1 1 1 0 RIO1 family GYD PF08734.11 CBZ38089.1 - 0.0087 16.0 0.0 0.033 14.1 0.0 2.0 1 0 0 1 1 1 1 GYD domain GAF_2 PF13185.6 CBZ38089.1 - 0.012 15.9 0.4 0.068 13.5 0.2 2.6 2 1 0 2 2 2 0 GAF domain PspA_IM30 PF04012.12 CBZ38089.1 - 0.057 13.0 1.1 0.13 11.9 1.1 1.5 1 0 0 1 1 1 0 PspA/IM30 family TRAF_BIRC3_bd PF16673.5 CBZ38089.1 - 0.14 12.0 0.3 0.26 11.1 0.3 1.4 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain Ribosomal_L5e PF17144.4 CBZ38090.1 - 2.6e-76 255.2 0.7 4e-76 254.5 0.7 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CBZ38090.1 - 3.7e-26 91.9 5.6 3.7e-26 91.9 5.6 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region P53_C PF11619.8 CBZ38090.1 - 0.0011 19.0 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 2 Transcription factor P53 - C terminal domain Ribosomal_L18p PF00861.22 CBZ38090.1 - 0.011 16.1 1.0 0.022 15.1 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Ribosomal_L15e PF00827.17 CBZ38091.1 - 1.7e-85 285.6 7.4 2e-85 285.3 7.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 Ribosomal_L36e PF01158.18 CBZ38092.1 - 1.5e-28 98.9 1.8 1.7e-28 98.7 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PHD PF00628.29 CBZ38094.1 - 0.00097 19.0 1.5 0.00097 19.0 1.5 1.8 2 0 0 2 2 2 1 PHD-finger PHD_Oberon PF07227.11 CBZ38094.1 - 0.077 12.9 3.8 0.28 11.1 2.0 2.1 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein C1_1 PF00130.22 CBZ38094.1 - 0.082 12.8 8.7 0.046 13.6 4.7 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 CBZ38094.1 - 0.48 10.4 5.4 0.98 9.4 5.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Atg14 PF10186.9 CBZ38095.1 - 0.008 15.3 5.2 0.013 14.7 5.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 TMCO5 PF14992.6 CBZ38095.1 - 0.021 14.4 3.5 0.04 13.5 3.5 1.4 1 0 0 1 1 1 0 TMCO5 family UPF0184 PF03670.13 CBZ38095.1 - 0.038 14.4 1.0 0.11 12.9 1.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) SHE3 PF17078.5 CBZ38095.1 - 1.1 9.0 6.7 1.7 8.3 6.7 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TMF_TATA_bd PF12325.8 CBZ38095.1 - 2.8 8.2 9.5 6 7.1 9.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding OmpH PF03938.14 CBZ38095.1 - 3.1 8.1 7.5 5.5 7.3 7.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DivIC PF04977.15 CBZ38095.1 - 4 7.3 7.4 20 5.1 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator CENP-H PF05837.12 CBZ38095.1 - 4.3 7.8 9.6 8.1 6.9 9.6 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) PRKG1_interact PF15898.5 CBZ38095.1 - 5.9 7.8 11.8 10 7.1 1.6 2.8 1 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain TolA_bind_tri PF16331.5 CBZ38095.1 - 6.4 6.9 14.0 5.3 7.2 10.6 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation YabA PF06156.13 CBZ38095.1 - 7.3 7.3 8.1 30 5.3 1.6 2.5 1 1 1 2 2 2 0 Initiation control protein YabA NYD-SP28_assoc PF14775.6 CBZ38095.1 - 7.5 6.7 10.2 1.5 9.0 1.6 2.4 1 1 1 2 2 2 0 Sperm tail C-terminal domain Cep57_CLD_2 PF14197.6 CBZ38095.1 - 9.2 6.4 17.2 2.4e+02 1.9 17.2 2.3 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 ATP11 PF06644.11 CBZ38096.1 - 1.8e-21 77.1 1.1 3.2e-21 76.3 1.1 1.4 1 1 0 1 1 1 1 ATP11 protein Lysine_decarbox PF03641.14 CBZ38097.1 - 3.6e-14 53.0 0.4 1.2e-13 51.3 0.0 1.8 1 1 1 2 2 2 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CBZ38097.1 - 1.2e-12 47.7 0.7 2.5e-11 43.4 0.7 2.2 1 1 0 1 1 1 1 SLOG cluster4 family UBX PF00789.20 CBZ38098.1 - 5.3e-07 29.8 0.1 2.2e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.6 CBZ38098.1 - 0.09 13.0 2.7 0.18 12.0 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin-like TALPID3 PF15324.6 CBZ38098.1 - 0.21 9.2 9.9 0.28 8.8 9.9 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Asp-B-Hydro_N PF05279.11 CBZ38098.1 - 2.1 8.4 14.6 3 7.8 14.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF572 PF04502.13 CBZ38098.1 - 2.6 7.6 11.1 3.8 7.0 11.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4569 PF15133.6 CBZ38098.1 - 2.6 7.7 4.3 3.6 7.2 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) HAUS6_N PF14661.6 CBZ38098.1 - 3.7 7.1 11.7 5.7 6.5 11.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Presenilin PF01080.17 CBZ38098.1 - 4.8 5.8 5.4 6.3 5.4 5.4 1.1 1 0 0 1 1 1 0 Presenilin ARGLU PF15346.6 CBZ38098.1 - 5.5 6.8 29.9 9.6 6.1 29.9 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF658 PF04936.12 CBZ38099.1 - 0.065 13.0 0.9 1.2 8.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF658) Peptidase_S55 PF05580.12 CBZ38099.1 - 0.19 11.7 0.1 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 SpoIVB peptidase S55 U3_assoc_6 PF08640.11 CBZ38100.1 - 1.6e-16 60.2 0.2 6.2e-16 58.2 0.2 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 HemY_N PF07219.13 CBZ38100.1 - 1.1 9.5 7.3 0.19 12.0 2.1 2.6 2 0 0 2 2 2 0 HemY protein N-terminus RmlD_sub_bind PF04321.17 CBZ38102.1 - 0.00012 21.3 0.0 0.05 12.7 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Sulfatase_C PF14707.6 CBZ38102.1 - 0.15 12.8 0.0 0.32 11.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase AAA_lid_7 PF17867.1 CBZ38102.1 - 0.17 12.1 0.1 0.6 10.3 0.0 1.9 2 0 0 2 2 2 0 Midasin AAA lid domain EF-hand_6 PF13405.6 CBZ38103.1 - 7e-09 34.9 0.1 0.2 11.7 0.0 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CBZ38103.1 - 6.1e-07 28.5 0.0 0.25 11.0 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CBZ38103.1 - 4.2e-05 23.9 0.0 1 9.9 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ38103.1 - 0.0051 16.2 0.2 0.49 10.0 0.2 2.4 2 0 0 2 2 2 1 EF hand Ank_2 PF12796.7 CBZ38104.1 - 6.1e-63 209.4 21.1 1.8e-09 38.0 0.0 14.4 12 3 4 16 16 16 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ38104.1 - 2e-33 114.3 22.5 0.00043 20.8 0.0 15.0 12 4 6 18 18 18 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 CBZ38104.1 - 4.8e-32 109.6 37.1 1.4e-06 28.5 0.4 17.9 15 4 5 20 20 20 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ38104.1 - 1.7e-25 86.2 32.2 0.012 16.1 0.1 19.1 20 0 0 20 20 20 6 Ankyrin repeat Ank PF00023.30 CBZ38104.1 - 6.2e-25 86.5 50.0 0.036 14.5 0.1 18.1 19 1 0 19 19 19 8 Ankyrin repeat Filamin PF00630.19 CBZ38104.1 - 0.0098 16.7 0.0 0.069 14.0 0.0 2.3 2 0 0 2 2 2 1 Filamin/ABP280 repeat TetR_C_36 PF18598.1 CBZ38104.1 - 0.066 13.2 0.3 0.31 11.0 0.3 2.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L32e PF01655.18 CBZ38105.1 - 1.3e-39 134.9 0.2 1.6e-39 134.7 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 SH3_9 PF14604.6 CBZ38106.1 - 7.8e-33 112.1 1.6 2.7e-12 46.3 0.0 4.8 5 0 0 5 5 5 3 Variant SH3 domain SH3_1 PF00018.28 CBZ38106.1 - 5.1e-29 99.6 0.2 5.2e-12 45.2 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 CBZ38106.1 - 9.3e-25 86.1 0.7 5.4e-12 45.2 0.1 3.8 4 0 0 4 4 4 3 Variant SH3 domain DUF4205 PF13898.6 CBZ38107.1 - 7.7e-24 84.3 0.0 1.3e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) DUF1180 PF06679.12 CBZ38108.1 - 0.92 9.9 3.6 0.38 11.1 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) E1-E2_ATPase PF00122.20 CBZ38109.1 - 2.8e-43 147.5 1.7 2.8e-43 147.5 1.7 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CBZ38109.1 - 3.1e-27 95.5 2.4 3.1e-27 95.5 2.4 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CBZ38109.1 - 7.2e-16 59.1 0.0 2.7e-14 54.0 0.0 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CBZ38109.1 - 7.1e-15 54.9 0.1 1.8e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CBZ38109.1 - 2.1e-10 40.2 0.0 5e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CBZ38109.1 - 1.5e-05 24.9 2.5 3.3e-05 23.7 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Kinesin PF00225.23 CBZ38110.1 - 4.2e-73 246.2 0.0 1.6e-43 148.9 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ38110.1 - 1.1e-22 80.6 0.0 2.3e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 CBZ38111.1 - 4.2e-73 246.2 0.0 1.6e-43 148.9 0.0 2.3 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ38111.1 - 1.1e-22 80.6 0.0 2.3e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Dpy-30 PF05186.13 CBZ38113.1 - 7.6 6.3 6.6 64 3.4 0.1 3.8 4 0 0 4 4 4 0 Dpy-30 motif Synaptobrevin PF00957.21 CBZ38114.1 - 5.2e-14 51.8 0.1 8.9e-14 51.1 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CBZ38114.1 - 4.1e-06 26.8 0.0 6.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain SDA1 PF05285.12 CBZ38115.1 - 0.0024 17.4 2.4 0.0025 17.3 2.4 1.2 1 0 0 1 1 1 1 SDA1 COPI_C PF06957.11 CBZ38115.1 - 0.024 13.4 1.2 0.031 13.1 1.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus EccE PF11203.8 CBZ38116.1 - 0.049 14.0 2.3 0.2 12.0 2.3 2.1 1 1 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE Lipase_3 PF01764.25 CBZ38117.1 - 0.00019 21.3 0.0 0.0008 19.3 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.13 CBZ38117.1 - 0.0019 18.0 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 CBZ38117.1 - 0.034 14.3 0.1 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain KIAA1430 PF13879.6 CBZ38117.1 - 0.11 13.2 3.7 3.9 8.3 0.6 2.4 2 0 0 2 2 2 0 KIAA1430 homologue Nup188 PF10487.9 CBZ38117.1 - 0.18 9.7 0.0 0.25 9.2 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 adh_short PF00106.25 CBZ38118.1 - 3.2e-18 65.9 0.1 5.1e-16 58.7 0.1 2.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ38118.1 - 3.2e-09 36.7 0.0 1.4e-07 31.4 0.0 2.7 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase HTH_8 PF02954.19 CBZ38118.1 - 0.0036 17.1 0.0 0.031 14.0 0.1 2.2 2 0 0 2 2 2 1 Bacterial regulatory protein, Fis family Asp_Arg_Hydrox PF05118.15 CBZ38118.1 - 0.17 11.7 0.0 22 4.8 0.0 2.5 3 0 0 3 3 3 0 Aspartyl/Asparaginyl beta-hydroxylase A_deaminase PF00962.22 CBZ38119.1 - 6.7e-58 196.6 0.0 8.4e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase adh_short PF00106.25 CBZ38120.1 - 1.8e-14 53.7 0.3 5.9e-14 52.0 0.1 2.0 3 0 0 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ38120.1 - 1.2e-08 34.8 1.2 1.1e-07 31.6 0.2 2.7 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ38120.1 - 0.00032 20.7 0.5 0.0017 18.3 0.6 2.0 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 CBZ38120.1 - 0.0066 16.4 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CBZ38120.1 - 0.0089 15.4 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.13 CBZ38120.1 - 0.17 11.4 0.4 0.44 10.1 0.1 1.7 2 0 0 2 2 2 0 NmrA-like family DUF1761 PF08570.10 CBZ38120.1 - 1.5 9.1 6.8 1.8 8.9 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1761) Ribosomal_L11_N PF03946.14 CBZ38122.1 - 8.1e-17 60.8 0.5 1.3e-16 60.1 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CBZ38122.1 - 7.4e-14 52.0 1.8 8.2e-14 51.9 0.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain RRM_1 PF00076.22 CBZ38123.1 - 7.5e-36 121.8 0.0 4.9e-17 61.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CBZ38123.1 - 3.5e-05 23.7 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CBZ38123.1 - 0.0046 17.0 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif KMP11 PF03037.16 CBZ38124.1 - 1.7e-55 185.8 18.2 1.9e-55 185.6 18.2 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 CBZ38124.1 - 0.003 17.4 4.1 0.0076 16.1 4.1 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 CBZ38124.1 - 0.03 13.2 1.7 0.031 13.2 1.7 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain PIN_8 PF18476.1 CBZ38124.1 - 0.083 12.7 5.6 0.091 12.6 5.6 1.0 1 0 0 1 1 1 0 PIN like domain TetR_C_15 PF17918.1 CBZ38124.1 - 0.12 13.2 1.8 11 6.8 0.1 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ZnuA PF01297.17 CBZ38124.1 - 0.18 11.1 3.6 1.5 8.1 0.2 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic YtxH PF12732.7 CBZ38124.1 - 0.24 12.0 2.5 1.2 9.7 2.5 1.9 1 1 0 1 1 1 0 YtxH-like protein TipAS PF07739.13 CBZ38124.1 - 0.24 11.9 10.5 0.39 11.3 4.0 2.0 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain DUF3987 PF13148.6 CBZ38124.1 - 0.35 9.8 4.8 0.21 10.5 3.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) YkuI_C PF10388.9 CBZ38124.1 - 1.1 9.0 7.6 0.64 9.8 6.0 1.5 1 1 0 1 1 1 0 EAL-domain associated signalling protein domain OmpH PF03938.14 CBZ38124.1 - 6.7 7.0 13.3 19 5.6 13.3 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) KMP11 PF03037.16 CBZ38125.1 - 2.1e-57 191.9 17.4 2.3e-57 191.7 17.4 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 CBZ38125.1 - 0.0023 17.8 3.5 0.0062 16.4 3.5 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 CBZ38125.1 - 0.021 13.7 1.2 0.021 13.7 1.2 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain PIN_8 PF18476.1 CBZ38125.1 - 0.036 13.9 5.5 0.037 13.9 5.5 1.0 1 0 0 1 1 1 0 PIN like domain TetR_C_15 PF17918.1 CBZ38125.1 - 0.12 13.1 1.9 11 6.8 0.1 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3987 PF13148.6 CBZ38125.1 - 0.13 11.2 3.0 0.17 10.9 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) YtxH PF12732.7 CBZ38125.1 - 0.18 12.4 2.1 0.87 10.2 2.1 1.9 1 1 0 1 1 1 0 YtxH-like protein ZnuA PF01297.17 CBZ38125.1 - 0.27 10.6 4.4 1.6 8.1 0.2 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic TipAS PF07739.13 CBZ38125.1 - 0.28 11.8 10.3 0.46 11.1 3.9 2.0 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain DUF2884 PF11101.8 CBZ38125.1 - 1.8 8.0 8.5 3.2 7.2 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) OmpH PF03938.14 CBZ38125.1 - 5 7.5 12.7 14 6.0 12.7 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Vma12 PF11712.8 CBZ38125.1 - 9.7 6.3 8.4 15 5.6 5.8 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase KMP11 PF03037.16 CBZ38126.1 - 2.1e-57 191.9 17.4 2.3e-57 191.7 17.4 1.0 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Apolipoprotein PF01442.18 CBZ38126.1 - 0.0023 17.8 3.5 0.0062 16.4 3.5 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Lyase_8_N PF08124.11 CBZ38126.1 - 0.021 13.7 1.2 0.021 13.7 1.2 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain PIN_8 PF18476.1 CBZ38126.1 - 0.036 13.9 5.5 0.037 13.9 5.5 1.0 1 0 0 1 1 1 0 PIN like domain TetR_C_15 PF17918.1 CBZ38126.1 - 0.12 13.1 1.9 11 6.8 0.1 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3987 PF13148.6 CBZ38126.1 - 0.13 11.2 3.0 0.17 10.9 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) YtxH PF12732.7 CBZ38126.1 - 0.18 12.4 2.1 0.87 10.2 2.1 1.9 1 1 0 1 1 1 0 YtxH-like protein ZnuA PF01297.17 CBZ38126.1 - 0.27 10.6 4.4 1.6 8.1 0.2 2.0 1 1 1 2 2 2 0 Zinc-uptake complex component A periplasmic TipAS PF07739.13 CBZ38126.1 - 0.28 11.8 10.3 0.46 11.1 3.9 2.0 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain DUF2884 PF11101.8 CBZ38126.1 - 1.8 8.0 8.5 3.2 7.2 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) OmpH PF03938.14 CBZ38126.1 - 5 7.5 12.7 14 6.0 12.7 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Vma12 PF11712.8 CBZ38126.1 - 9.7 6.3 8.4 15 5.6 5.8 2.3 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ATG_C PF09333.11 CBZ38129.1 - 0.0015 18.9 0.1 0.042 14.2 0.1 2.8 1 1 0 1 1 1 1 Autophagy-related protein C terminal domain ATP-grasp_4 PF13535.6 CBZ38130.1 - 4.3e-08 32.9 0.0 1.3e-06 28.1 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 CBZ38130.1 - 1e-05 25.6 0.4 3.1e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 L-amino acid ligase C-terminal domain 2 ATPgrasp_Ter PF15632.6 CBZ38130.1 - 0.00041 20.1 0.3 0.23 11.2 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 CBZ38130.1 - 0.0049 16.9 0.0 0.076 13.1 0.0 2.5 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CBZ38130.1 - 0.075 12.5 0.0 5.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Helicase_C PF00271.31 CBZ38131.1 - 2.3e-08 34.4 0.0 4.9e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ38131.1 - 0.00018 21.4 0.0 0.0004 20.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ38131.1 - 0.068 13.4 0.1 0.38 11.0 0.0 2.2 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 CBZ38136.1 - 9.9e-42 143.1 0.2 5.3e-23 81.7 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38136.1 - 2e-26 92.8 0.0 1.8e-22 79.9 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CBZ38136.1 - 0.0001 21.8 0.0 0.066 12.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pox_ser-thr_kin PF05445.11 CBZ38136.1 - 0.28 10.1 0.1 0.42 9.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CBP_BcsO PF17037.5 CBZ38136.1 - 7.9 6.6 11.2 0.37 10.9 4.5 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO HEAT_EZ PF13513.6 CBZ38137.1 - 1.9e-06 28.2 9.1 0.011 16.2 0.0 5.9 5 1 1 6 6 6 2 HEAT-like repeat 2Fe-2S_thioredx PF01257.19 CBZ38137.1 - 0.00074 19.4 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin TAF6_C PF07571.13 CBZ38137.1 - 0.0075 16.6 0.1 33 4.9 0.0 4.3 4 1 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain HEAT PF02985.22 CBZ38137.1 - 0.0076 16.4 10.8 53 4.5 0.2 7.5 7 0 0 7 7 7 0 HEAT repeat RIX1 PF08167.12 CBZ38137.1 - 0.012 15.4 1.0 6.2 6.5 0.0 3.6 3 2 1 4 4 4 0 rRNA processing/ribosome biogenesis UME PF08064.13 CBZ38137.1 - 0.034 14.1 1.3 0.99 9.3 0.4 3.5 2 1 0 2 2 2 0 UME (NUC010) domain TrbC PF04956.13 CBZ38137.1 - 0.052 13.8 0.2 0.54 10.5 0.0 2.5 2 0 0 2 2 2 0 TrbC/VIRB2 family IBN_N PF03810.19 CBZ38137.1 - 0.058 13.3 0.9 0.28 11.1 0.9 2.2 1 0 0 1 1 1 0 Importin-beta N-terminal domain Adaptin_N PF01602.20 CBZ38137.1 - 0.16 10.5 0.1 0.34 9.4 0.1 1.4 1 0 0 1 1 1 0 Adaptin N terminal region CAF1 PF04857.20 CBZ38138.1 - 2.3e-56 191.3 0.0 2.9e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease Peptidase_M24 PF00557.24 CBZ38139.1 - 2.1e-51 174.6 0.7 3.2e-51 174.0 0.7 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CBZ38139.1 - 9.2e-24 83.5 0.0 2.4e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain EGF PF00008.27 CBZ38139.1 - 0.044 14.1 2.8 0.093 13.1 2.8 1.6 1 0 0 1 1 1 0 EGF-like domain DUF1764 PF08576.10 CBZ38140.1 - 5.1e-07 30.5 1.6 5.1e-07 30.5 1.6 2.6 1 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) SET PF00856.28 CBZ38141.1 - 0.00058 20.3 0.0 0.0082 16.5 0.0 2.5 2 1 1 3 3 3 1 SET domain Spt4 PF06093.13 CBZ38143.1 - 6.6e-10 39.0 0.0 8.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger ANAPC4_WD40 PF12894.7 CBZ38144.1 - 6.9e-05 23.1 0.0 0.027 14.8 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CBZ38144.1 - 7.7e-05 22.4 0.1 0.00029 20.5 0.1 2.0 1 0 0 1 1 1 1 PQQ-like domain WD40 PF00400.32 CBZ38144.1 - 0.00021 22.0 0.2 9 7.4 0.0 5.0 6 0 0 6 6 6 1 WD domain, G-beta repeat LRR_6 PF13516.6 CBZ38144.1 - 0.037 14.1 0.2 17 5.8 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich repeat Arc_C PF18162.1 CBZ38144.1 - 0.062 13.2 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Arc C-lobe UCH PF00443.29 CBZ38145.1 - 2.3e-36 125.6 0.0 1.2e-29 103.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CBZ38145.1 - 5.6e-12 45.9 0.0 2.8e-09 37.0 0.0 3.3 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf_UBZ PF18439.1 CBZ38145.1 - 8.6 6.0 9.1 2.4 7.8 0.2 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Vps5 PF09325.10 CBZ38146.1 - 1.4e-16 60.8 4.1 2e-16 60.2 4.1 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CBZ38146.1 - 2e-16 60.0 0.0 3.8e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 CBZ38146.1 - 0.0043 16.6 0.9 0.017 14.6 0.9 1.8 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein P4Ha_N PF08336.11 CBZ38146.1 - 0.025 14.6 0.4 0.68 9.9 0.0 2.6 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF5405 PF17399.2 CBZ38146.1 - 0.059 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5405) DUF4164 PF13747.6 CBZ38146.1 - 0.089 13.1 5.5 0.42 10.9 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Sec16_N PF12935.7 CBZ38147.1 - 1.7 8.8 4.6 1.7 8.7 0.6 2.4 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 N-terminus FAA_hydrolase PF01557.18 CBZ38148.1 - 8.1e-39 133.5 0.1 1.3e-37 129.6 0.1 2.0 1 1 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3490 PF11995.8 CBZ38148.1 - 0.00029 20.7 0.0 0.00077 19.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3490) HECT PF00632.25 CBZ38149.1 - 3.1e-81 273.2 0.0 5.7e-81 272.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IBR PF01485.21 CBZ38149.1 - 0.23 11.7 4.9 0.63 10.3 4.9 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain ZZ PF00569.17 CBZ38149.1 - 0.99 9.3 8.6 3 7.7 8.6 1.8 1 0 0 1 1 1 0 Zinc finger, ZZ type C1_2 PF03107.16 CBZ38149.1 - 2.8 8.3 8.0 7.7 6.9 8.0 1.8 1 0 0 1 1 1 0 C1 domain DUF3492 PF11997.8 CBZ38150.1 - 1.7 8.3 4.0 0.47 10.2 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3492) Nop53 PF07767.11 CBZ38151.1 - 7.7e-17 61.8 16.2 1.9e-16 60.5 16.2 1.6 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Cystatin PF00031.21 CBZ38151.1 - 0.39 11.0 4.7 0.12 12.6 0.6 2.3 2 1 0 2 2 2 0 Cystatin domain FPP PF05911.11 CBZ38152.1 - 0.0009 17.6 12.6 0.0014 16.9 12.6 1.3 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil 7TMR-HDED PF07697.11 CBZ38152.1 - 0.043 13.9 7.4 0.1 12.7 7.4 1.7 1 0 0 1 1 1 0 7TM-HD extracellular MMR1 PF08505.10 CBZ38152.1 - 4 7.6 10.9 9 6.5 10.9 1.5 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Fez1 PF06818.15 CBZ38152.1 - 7.2 7.0 17.8 16 5.9 17.8 1.5 1 0 0 1 1 1 0 Fez1 Phage_Nu1 PF07471.12 CBZ38152.1 - 7.3 6.3 11.0 19 5.0 11.0 1.6 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 V_ATPase_I PF01496.19 CBZ38152.1 - 7.4 4.3 11.2 11 3.8 11.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EcKinase PF02958.20 CBZ38152.1 - 7.8 5.7 9.9 13 5.0 9.9 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase CorA PF01544.18 CBZ38152.1 - 8.5 5.6 7.7 17 4.6 7.7 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Cupin_6 PF12852.7 CBZ38153.1 - 0.1 12.3 3.4 0.18 11.5 0.1 2.6 3 0 0 3 3 3 0 Cupin Propep_M14 PF02244.16 CBZ38153.1 - 0.14 12.6 0.1 0.35 11.3 0.1 1.6 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Yos1 PF08571.10 CBZ38154.1 - 1.7e-25 89.1 0.1 2.6e-25 88.5 0.1 1.3 1 1 0 1 1 1 1 Yos1-like zf-RING_2 PF13639.6 CBZ38155.1 - 3.7e-09 36.8 14.4 0.00012 22.4 0.2 3.7 3 1 0 3 3 3 2 Ring finger domain zf-RING_11 PF17123.5 CBZ38155.1 - 1.5e-06 27.9 3.1 0.001 18.7 0.3 3.9 4 0 0 4 4 4 2 RING-like zinc finger zf-RING_5 PF14634.6 CBZ38155.1 - 1.2e-05 25.2 6.4 0.0021 18.0 0.8 4.1 3 3 0 4 4 4 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 CBZ38155.1 - 0.00011 22.1 21.6 0.023 14.7 0.2 5.2 5 0 0 5 5 5 2 RING-type zinc-finger IQ PF00612.27 CBZ38155.1 - 0.00016 21.1 1.6 0.00059 19.4 1.6 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Eapp_C PF10238.9 CBZ38155.1 - 0.087 12.9 3.9 41 4.2 0.0 3.6 3 1 1 4 4 4 0 E2F-associated phosphoprotein zf-C3HC4_2 PF13923.6 CBZ38155.1 - 0.12 12.3 0.1 0.12 12.3 0.1 5.1 5 0 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 CBZ38155.1 - 0.33 11.1 0.1 0.33 11.1 0.1 3.5 3 1 0 3 3 3 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 CBZ38155.1 - 0.62 9.7 12.9 0.51 10.0 0.1 3.5 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CBZ38155.1 - 2.1 8.3 28.1 3.4 7.6 4.0 5.2 4 1 0 4 4 4 0 Prokaryotic RING finger family 4 CS PF04969.16 CBZ38156.1 - 0.25 12.4 1.0 0.5 11.4 1.0 1.5 1 1 0 1 1 1 0 CS domain DctQ PF04290.12 CBZ38157.1 - 0.13 12.2 11.5 0.055 13.4 7.9 1.9 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component SUR7 PF06687.12 CBZ38157.1 - 1.2 8.7 13.0 0.078 12.6 7.2 1.8 1 1 0 2 2 2 0 SUR7/PalI family RRM_1 PF00076.22 CBZ38158.1 - 1.8e-15 56.5 0.0 3.3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CBZ38158.1 - 0.0053 16.9 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif FAD_binding_1 PF00667.20 CBZ38159.1 - 1.9e-28 99.5 0.0 3.1e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CBZ38159.1 - 3.7e-17 62.9 0.5 2e-12 47.5 0.0 2.9 3 0 0 3 3 3 2 Flavodoxin FAD_binding_6 PF00970.24 CBZ38159.1 - 0.00017 21.9 0.0 0.0014 19.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CBZ38159.1 - 0.0063 17.1 0.1 0.11 13.1 0.1 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Acetyltransf_16 PF05301.11 CBZ38160.1 - 0.22 11.3 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 FixS PF03597.15 CBZ38161.1 - 0.029 14.1 0.3 0.052 13.3 0.3 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DHHC PF01529.20 CBZ38162.1 - 9.2e-26 90.5 10.5 9.2e-26 90.5 10.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Phage_holin_3_6 PF07332.11 CBZ38162.1 - 0.016 15.2 4.5 0.063 13.3 0.2 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1772 PF08592.11 CBZ38162.1 - 0.033 14.5 6.9 0.13 12.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) YwiC PF14256.6 CBZ38162.1 - 0.046 14.0 0.2 0.046 14.0 0.2 2.2 2 0 0 2 2 2 0 YwiC-like protein DUF2749 PF10907.8 CBZ38162.1 - 0.074 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Transgly_assoc PF04226.13 CBZ38162.1 - 0.53 10.6 8.3 0.65 10.3 1.3 2.5 2 0 0 2 2 2 0 Transglycosylase associated protein NIF PF03031.18 CBZ38165.1 - 7e-28 97.4 0.3 1.4e-27 96.4 0.1 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase zf-HC5HC2H PF13771.6 CBZ38166.1 - 6.7e-06 26.3 8.5 6.7e-06 26.3 8.5 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CBZ38166.1 - 0.00022 21.3 9.0 0.00022 21.3 9.0 2.5 2 1 0 2 2 2 1 PHD-zinc-finger like domain TruD PF01142.18 CBZ38167.1 - 0.00015 20.8 0.2 0.24 10.2 0.1 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) PAC1 PF16094.5 CBZ38169.1 - 4.5 6.3 6.1 8.7 5.4 3.9 2.2 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Ank_2 PF12796.7 CBZ38170.1 - 1.4e-21 76.9 0.8 4e-15 56.2 0.3 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CBZ38170.1 - 4.2e-21 75.0 5.2 3.4e-10 40.3 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CBZ38170.1 - 1.2e-20 73.0 1.7 4.9e-11 42.5 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CBZ38170.1 - 8.6e-19 65.7 0.4 2.2e-06 27.5 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CBZ38170.1 - 3.6e-17 62.2 5.6 1.8e-10 40.9 0.6 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) HSBP1 PF06825.12 CBZ38171.1 - 3.9e-24 84.3 5.8 4.5e-24 84.1 5.8 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF4618 PF15397.6 CBZ38171.1 - 0.0069 15.8 0.3 0.0077 15.7 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) BORCS6 PF10157.9 CBZ38171.1 - 0.0073 16.5 0.2 0.0094 16.2 0.2 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Matrilin_ccoil PF10393.9 CBZ38171.1 - 0.01 15.7 0.1 0.16 11.9 0.1 2.1 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin IL11 PF07400.11 CBZ38171.1 - 0.018 14.7 0.4 0.098 12.3 0.4 1.8 1 1 1 2 2 2 0 Interleukin 11 BLOC1_2 PF10046.9 CBZ38171.1 - 0.019 15.3 0.2 0.024 14.9 0.2 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PhoU_div PF01865.16 CBZ38171.1 - 0.019 14.3 0.6 0.023 14.0 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function DUF47 Trimer_CC PF08954.11 CBZ38171.1 - 0.019 14.5 0.4 0.72 9.5 0.1 2.3 1 1 1 2 2 2 0 Trimerisation motif Apolipoprotein PF01442.18 CBZ38171.1 - 0.024 14.5 0.1 0.028 14.3 0.1 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fzo_mitofusin PF04799.13 CBZ38171.1 - 0.043 13.4 0.6 0.045 13.3 0.6 1.0 1 0 0 1 1 1 0 fzo-like conserved region Hemagglutinin PF00509.18 CBZ38171.1 - 0.052 12.0 0.1 0.057 11.8 0.1 1.0 1 0 0 1 1 1 0 Haemagglutinin DUF16 PF01519.16 CBZ38171.1 - 0.053 14.0 0.1 0.076 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Nsp1_C PF05064.13 CBZ38171.1 - 0.058 13.2 0.4 0.068 13.0 0.4 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region Allexi_40kDa PF05549.11 CBZ38171.1 - 0.065 12.7 0.4 0.072 12.6 0.4 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein CLZ PF16526.5 CBZ38171.1 - 0.08 13.3 0.4 0.16 12.3 0.2 1.5 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MtrB PF05440.12 CBZ38171.1 - 0.092 13.2 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B YojJ PF10372.9 CBZ38171.1 - 0.11 12.7 1.2 0.14 12.3 1.2 1.2 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus DUF4351 PF14261.6 CBZ38171.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4351) DUF948 PF06103.11 CBZ38171.1 - 0.12 12.7 0.7 9 6.6 0.1 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YvrJ PF12841.7 CBZ38171.1 - 0.14 11.7 0.1 0.61 9.7 0.1 2.0 1 1 1 2 2 2 0 YvrJ protein family XhlA PF10779.9 CBZ38171.1 - 0.15 12.3 0.4 0.25 11.6 0.3 1.4 1 1 0 1 1 1 0 Haemolysin XhlA BTB_2 PF02214.22 CBZ38172.1 - 6.5e-12 45.6 0.0 2.3e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Atg14 PF10186.9 CBZ38172.1 - 0.042 12.9 0.1 0.062 12.4 0.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TRAPPC9-Trs120 PF08626.11 CBZ38173.1 - 0.00046 17.7 0.0 0.0027 15.1 0.0 2.2 3 0 0 3 3 3 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SNARE PF05739.19 CBZ38175.1 - 2.8e-12 46.5 0.3 8.3e-12 44.9 0.3 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CBZ38175.1 - 0.00013 21.7 17.2 0.00021 21.0 17.2 1.3 1 0 0 1 1 1 1 Syntaxin Lipoprotein_6 PF01441.19 CBZ38175.1 - 0.016 15.2 2.0 0.11 12.5 0.3 2.3 2 0 0 2 2 2 0 Lipoprotein Syntaxin_2 PF14523.6 CBZ38175.1 - 0.023 15.1 5.9 0.045 14.1 0.8 2.6 2 2 0 2 2 2 0 Syntaxin-like protein Syntaxin-5_N PF11416.8 CBZ38175.1 - 0.17 11.1 0.5 0.42 9.9 0.5 1.6 1 0 0 1 1 1 0 Syntaxin-5 N-terminal, Sly1p-binding domain PBECR5 PF18814.1 CBZ38175.1 - 3.6 7.5 12.3 0.34 10.8 5.9 2.0 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 SET PF00856.28 CBZ38176.1 - 0.014 15.7 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 SET domain Acyl-CoA_dh_1 PF00441.24 CBZ38177.1 - 1.8e-40 138.6 2.7 2.5e-40 138.1 2.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CBZ38177.1 - 4.9e-26 90.8 0.3 1.6e-25 89.1 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CBZ38177.1 - 1e-25 90.6 0.0 2.7e-25 89.2 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CBZ38177.1 - 1.5e-19 70.6 0.0 2.4e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CBZ38177.1 - 0.059 13.0 0.1 0.25 11.0 0.1 2.0 1 1 1 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal GalKase_gal_bdg PF10509.9 CBZ38178.1 - 3.4e-14 52.1 0.0 1.4e-13 50.2 0.0 2.2 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 CBZ38178.1 - 1.1e-08 35.3 2.8 1.9e-08 34.5 0.0 2.6 2 1 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CBZ38178.1 - 6e-08 32.8 0.1 1.2e-07 31.8 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Val_tRNA-synt_C PF10458.9 CBZ38179.1 - 9.6 6.6 13.7 14 6.0 5.5 4.0 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm MMR_HSR1 PF01926.23 CBZ38180.1 - 3e-06 27.3 0.0 6.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ38180.1 - 0.0046 16.5 0.0 0.013 15.0 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 CBZ38180.1 - 0.0051 17.2 0.9 0.016 15.6 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CBZ38180.1 - 0.13 12.5 0.1 7.3 6.9 0.0 2.6 1 1 0 2 2 2 0 AAA domain IQ PF00612.27 CBZ38181.1 - 0.00026 20.5 1.4 0.00078 19.0 1.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif MFS_1 PF07690.16 CBZ38182.1 - 2.3e-27 95.8 40.2 1.6e-22 79.9 15.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ38182.1 - 3.2e-11 42.8 10.3 3.2e-11 42.8 10.3 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter DUF5075 PF16825.5 CBZ38183.1 - 0.0018 18.0 0.5 0.0025 17.5 0.5 1.2 1 0 0 1 1 1 1 IGP family C-type lectin domain DUF2561 PF10812.8 CBZ38183.1 - 0.027 14.5 0.4 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) SCIMP PF15050.6 CBZ38183.1 - 0.1 13.1 0.1 0.1 13.1 0.1 1.7 2 0 0 2 2 2 0 SCIMP protein DUF4492 PF14899.6 CBZ38183.1 - 0.12 12.3 0.3 0.21 11.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) ATP-synt_8 PF00895.20 CBZ38183.1 - 0.16 12.5 1.9 0.44 11.0 1.9 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 TMIE PF16038.5 CBZ38183.1 - 0.26 11.2 1.3 0.57 10.1 1.3 1.5 1 0 0 1 1 1 0 TMIE protein Pox_EPC_I2-L1 PF12575.8 CBZ38183.1 - 0.77 10.0 2.3 2.2 8.6 2.3 1.7 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Orf78 PF06024.12 CBZ38183.1 - 1.6 9.1 3.0 0.67 10.3 0.1 1.9 2 0 0 2 2 2 0 Orf78 (ac78) Hydrolase_4 PF12146.8 CBZ38184.1 - 6.4e-07 28.9 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ38184.1 - 1.2e-06 28.3 0.1 1.9e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.12 CBZ38184.1 - 3.8e-05 22.8 0.0 5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.21 CBZ38184.1 - 0.00036 20.1 0.0 0.00054 19.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CBZ38184.1 - 0.0032 18.1 0.6 0.0089 16.6 0.1 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CBZ38184.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.9 CBZ38184.1 - 0.087 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Lipase_3 PF01764.25 CBZ38184.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) UPF0227 PF05728.12 CBZ38184.1 - 0.15 12.0 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2512 PF10710.9 CBZ38184.1 - 1.6 8.4 7.7 3.5 7.3 7.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) MFS_1 PF07690.16 CBZ38185.1 - 1.7e-20 73.2 15.9 1.7e-20 73.2 15.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CBZ38185.1 - 3e-10 39.5 3.9 3.2e-05 23.0 3.7 2.3 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 CBZ38185.1 - 1.7e-06 27.2 6.7 1.7e-06 27.2 6.7 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CBZ38185.1 - 0.0068 15.8 6.7 0.078 12.3 6.8 2.2 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 CBZ38185.1 - 0.01 14.5 6.5 0.018 13.6 6.5 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein MFS_1 PF07690.16 CBZ38186.1 - 1.2e-23 83.6 32.0 2e-19 69.8 6.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CBZ38186.1 - 5.1e-06 25.6 5.0 0.038 12.8 0.4 3.4 2 2 1 3 3 3 2 MFS_1 like family Sugar_tr PF00083.24 CBZ38186.1 - 1.8e-05 23.8 4.6 1.8e-05 23.8 4.6 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter Aminotran_5 PF00266.19 CBZ38188.1 - 2.5e-47 161.6 0.3 1.1e-28 100.3 0.1 2.3 1 1 1 2 2 2 2 Aminotransferase class-V Leo1 PF04004.13 CBZ38189.1 - 8.4e-10 38.7 7.0 5.5e-09 36.1 7.2 2.1 1 1 0 1 1 1 1 Leo1-like protein Alb1 PF09135.11 CBZ38190.1 - 0.00017 22.4 6.3 0.00017 22.4 6.3 2.2 1 1 0 2 2 2 1 Alb1 Agouti PF05039.12 CBZ38190.1 - 1.6 9.5 10.6 6.3 7.6 0.3 2.3 2 0 0 2 2 2 0 Agouti protein Pkinase PF00069.25 CBZ38191.1 - 1.1e-06 28.2 0.1 0.0011 18.5 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38191.1 - 2e-06 27.3 0.1 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Sybindin PF04099.12 CBZ38192.1 - 1.6e-16 60.5 0.0 1.8e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family CHU_C PF13585.6 CBZ38192.1 - 0.03 14.4 0.1 0.053 13.6 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain of CHU protein family SpoU_methylase PF00588.19 CBZ38193.1 - 1.1e-07 32.1 0.0 3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family NAGidase PF07555.13 CBZ38193.1 - 0.08 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase OrfB_IS605 PF01385.19 CBZ38193.1 - 6.3 7.0 7.8 1.7 8.9 1.2 2.8 3 0 0 3 3 3 0 Probable transposase Tctex-1 PF03645.13 CBZ38195.1 - 1.9e-27 95.5 0.1 2.2e-27 95.3 0.1 1.0 1 0 0 1 1 1 1 Tctex-1 family DSPc PF00782.20 CBZ38195.1 - 0.029 14.2 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF4200 PF13863.6 CBZ38196.1 - 0.0024 18.3 6.9 0.0024 18.3 6.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4200) FAM76 PF16046.5 CBZ38196.1 - 0.063 12.6 1.2 0.15 11.4 1.2 1.6 1 0 0 1 1 1 0 FAM76 protein Seryl_tRNA_N PF02403.22 CBZ38196.1 - 0.11 12.8 4.9 13 6.1 0.0 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain YabA PF06156.13 CBZ38196.1 - 0.49 11.1 2.7 1.6 9.4 2.7 1.9 1 0 0 1 1 1 0 Initiation control protein YabA Swi5 PF07061.11 CBZ38196.1 - 1.9 8.6 4.3 1.6 8.8 1.2 2.2 2 0 0 2 2 2 0 Swi5 T3SS_needle_F PF09392.10 CBZ38196.1 - 4.2 7.6 6.2 3.9 7.7 1.1 2.6 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF CCDC-167 PF15188.6 CBZ38196.1 - 8.3 6.8 8.0 6.5 7.2 6.1 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 FeoC PF09012.10 CBZ38197.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 FeoC like transcriptional regulator Cupin_8 PF13621.6 CBZ38198.1 - 5.1e-47 160.7 0.0 1.6e-46 159.1 0.0 1.8 2 0 0 2 2 2 1 Cupin-like domain LCM PF04072.14 CBZ38198.1 - 2.4e-16 60.2 0.1 3.1e-09 37.0 0.0 3.0 2 1 0 2 2 2 2 Leucine carboxyl methyltransferase Kelch_5 PF13854.6 CBZ38198.1 - 1.7e-08 34.3 0.5 0.83 9.7 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CBZ38198.1 - 1.6e-06 28.0 6.0 0.02 14.9 0.0 6.2 6 1 0 6 6 6 1 Galactose oxidase, central domain Kelch_6 PF13964.6 CBZ38198.1 - 8.8e-05 22.7 0.8 25 5.3 0.0 6.3 6 0 0 6 6 6 0 Kelch motif Kelch_3 PF13415.6 CBZ38198.1 - 0.00012 22.3 15.0 0.0086 16.3 0.1 5.7 5 0 0 5 5 5 2 Galactose oxidase, central domain Cupin_4 PF08007.12 CBZ38198.1 - 0.0002 20.9 0.0 0.00084 18.9 0.0 1.9 1 1 0 1 1 1 1 Cupin superfamily protein RAG2 PF03089.14 CBZ38198.1 - 0.00024 20.2 0.0 0.00063 18.8 0.0 1.5 1 1 0 1 1 1 1 Recombination activating protein 2 PriCT_2 PF08707.11 CBZ38198.1 - 0.14 12.6 0.3 0.42 11.0 0.3 1.9 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) PPR_2 PF13041.6 CBZ38199.1 - 9.6e-22 76.9 9.4 5.1e-07 29.8 0.0 7.8 6 2 2 8 8 8 6 PPR repeat family PPR PF01535.20 CBZ38199.1 - 3.8e-21 73.8 27.5 0.016 15.4 0.0 12.0 14 0 0 14 14 14 6 PPR repeat PPR_3 PF13812.6 CBZ38199.1 - 8.5e-11 41.8 10.7 0.034 14.2 0.1 7.3 5 1 4 9 9 9 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 CBZ38199.1 - 1.8e-10 40.3 0.0 0.46 10.2 0.0 6.0 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 CBZ38199.1 - 3.7e-06 26.5 10.8 2e-05 24.0 0.8 5.3 4 2 3 7 7 7 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CBZ38199.1 - 0.019 15.4 0.4 8.2 7.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SPOB_a PF14689.6 CBZ38199.1 - 1.7 8.4 5.5 57 3.5 0.1 4.6 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain DENN PF02141.21 CBZ38200.1 - 7e-24 84.8 0.5 1.2e-23 84.0 0.5 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 CBZ38200.1 - 0.085 13.6 0.0 0.22 12.3 0.0 1.8 1 0 0 1 1 1 0 uDENN domain TPR_14 PF13428.6 CBZ38201.1 - 0.00074 20.1 4.1 0.31 12.0 0.2 3.8 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ38201.1 - 0.0035 17.8 1.7 0.018 15.5 0.4 2.5 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ38201.1 - 0.0069 16.4 2.4 5.1 7.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ38201.1 - 0.008 16.3 0.4 7.7 7.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ38201.1 - 0.014 16.0 3.9 0.025 15.2 3.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ38201.1 - 0.019 15.2 0.3 0.033 14.4 0.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CBZ38201.1 - 0.068 13.8 0.1 0.29 11.9 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Alpha_adaptin_C PF02296.16 CBZ38201.1 - 0.085 13.0 0.0 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain TPR_1 PF00515.28 CBZ38201.1 - 0.14 12.1 1.7 13 5.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ38201.1 - 0.34 10.8 2.1 1.9 8.5 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaJ_C PF01556.18 CBZ38202.1 - 2.6e-31 108.7 0.1 3.4e-31 108.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ38202.1 - 3.9e-22 78.1 1.8 9e-22 77.0 0.9 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CBZ38202.1 - 9.7e-15 54.7 19.9 2e-14 53.7 19.9 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CBZ38202.1 - 0.2 11.6 13.9 0.088 12.8 3.6 3.0 1 1 2 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CBZ38202.1 - 0.39 10.8 7.8 3.8 7.6 1.3 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_pol_A_exo1 PF01612.20 CBZ38203.1 - 8.1e-16 58.2 0.0 1.2e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2_10 PF16588.5 CBZ38203.1 - 0.00016 21.3 27.5 0.012 15.4 2.8 3.7 4 0 0 4 4 4 3 C2H2 zinc-finger zf-CCHC PF00098.23 CBZ38203.1 - 0.00041 20.3 32.2 0.0041 17.1 2.3 4.7 4 1 0 4 4 4 3 Zinc knuckle zf-C4_ClpX PF06689.13 CBZ38203.1 - 0.72 9.8 10.4 0.94 9.4 1.3 2.7 2 0 0 2 2 2 0 ClpX C4-type zinc finger CLIP1_ZNF PF16641.5 CBZ38203.1 - 9.6 6.2 9.6 1.3 9.0 0.5 3.4 3 0 0 3 3 3 0 CLIP1 zinc knuckle Glyoxalase PF00903.25 CBZ38205.1 - 2e-14 53.9 0.2 2.6e-14 53.5 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CBZ38205.1 - 2.8e-08 34.0 0.0 4.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 CBZ38205.1 - 0.0028 17.7 0.0 0.0035 17.4 0.0 1.2 1 0 0 1 1 1 1 CppA N-terminal Glyoxalase_2 PF12681.7 CBZ38205.1 - 0.0075 16.2 0.1 0.029 14.3 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 CBZ38205.1 - 0.037 14.1 0.0 3.3 7.8 0.0 2.4 1 1 1 2 2 2 0 Glyoxalase-like domain PAF-AH_p_II PF03403.13 CBZ38206.1 - 8e-31 106.9 0.0 2.1e-30 105.5 0.0 1.6 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 CBZ38206.1 - 4.8e-07 30.6 0.1 7.1e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CBZ38206.1 - 1.1e-05 24.5 0.0 6.8e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CBZ38206.1 - 0.00049 19.4 0.0 0.85 8.8 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ38206.1 - 0.0049 16.5 0.1 0.033 13.8 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 CBZ38206.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) SNARE_assoc PF09335.11 CBZ38206.1 - 0.18 12.3 1.9 0.47 10.9 0.8 2.2 2 0 0 2 2 2 0 SNARE associated Golgi protein ICMT PF04140.14 CBZ38207.1 - 7.4e-19 68.0 3.0 7.4e-19 68.0 3.0 2.1 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CBZ38207.1 - 5e-06 26.9 2.4 5e-06 26.9 2.4 3.1 3 2 1 4 4 4 1 Phospholipid methyltransferase DUF1295 PF06966.12 CBZ38207.1 - 0.0041 16.7 2.9 0.0041 16.7 2.9 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF1295) DUF2721 PF11026.8 CBZ38207.1 - 0.048 13.5 4.1 0.29 11.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) OST3_OST6 PF04756.13 CBZ38207.1 - 0.05 12.9 0.7 0.068 12.5 0.0 1.5 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family RseC_MucC PF04246.12 CBZ38207.1 - 1 9.3 3.3 0.42 10.6 0.2 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC NDUFA12 PF05071.16 CBZ38208.1 - 3.8e-05 24.5 1.9 0.00014 22.6 1.9 2.0 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 zf-CCHC_2 PF13696.6 CBZ38209.1 - 5.4e-08 32.5 8.2 9.7e-08 31.7 8.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-RING_4 PF14570.6 CBZ38209.1 - 0.015 15.0 0.9 0.015 15.0 0.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_14 PF17978.1 CBZ38209.1 - 0.044 14.2 0.3 0.092 13.2 0.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CCHC PF00098.23 CBZ38209.1 - 0.096 12.8 4.5 0.22 11.6 4.5 1.7 1 0 0 1 1 1 0 Zinc knuckle FYVE PF01363.21 CBZ38209.1 - 2.2 8.5 5.8 0.6 10.3 1.2 2.2 2 1 0 2 2 2 0 FYVE zinc finger zf-CCHC_3 PF13917.6 CBZ38209.1 - 2.3 8.3 5.3 1.1 9.2 0.4 2.3 2 0 0 2 2 2 0 Zinc knuckle TF_Zn_Ribbon PF08271.12 CBZ38209.1 - 3.1 7.4 8.3 0.77 9.3 2.7 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding zf-RING_5 PF14634.6 CBZ38209.1 - 4.7 7.3 8.8 3 7.9 3.2 2.4 2 0 0 2 2 2 0 zinc-RING finger domain ThiF PF00899.21 CBZ38210.1 - 4.3e-74 248.9 0.0 1.5e-57 194.8 0.0 2.2 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CBZ38210.1 - 3.7e-58 197.4 0.1 5.4e-58 196.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_4HB PF16191.5 CBZ38210.1 - 4.1e-11 42.9 0.0 8.8e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Rhamno_transf PF11316.8 CBZ38210.1 - 0.042 13.2 0.1 0.078 12.4 0.1 1.4 1 0 0 1 1 1 0 Putative rhamnosyl transferase PglD_N PF17836.1 CBZ38210.1 - 0.057 14.1 0.0 0.17 12.6 0.0 1.8 1 0 0 1 1 1 0 PglD N-terminal domain 3HCDH_N PF02737.18 CBZ38210.1 - 0.074 12.9 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CBZ38210.1 - 0.12 11.7 0.0 0.39 10.1 0.0 1.8 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lipocalin_9 PF17186.4 CBZ38211.1 - 8.9e-06 26.0 0.0 4e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Lipocalin-like domain FGGY_N PF00370.21 CBZ38212.1 - 9.1e-68 228.4 0.0 1.2e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CBZ38212.1 - 3.4e-60 203.2 1.2 7.5e-60 202.0 1.1 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DnaJ PF00226.31 CBZ38213.1 - 1.1e-09 38.2 0.0 2.7e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Babuvirus_MP PF07234.11 CBZ38213.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Movement and RNA silencing protein DEAD PF00270.29 CBZ38214.1 - 9.3e-43 146.0 0.0 1.6e-41 142.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ38214.1 - 6.7e-31 106.9 0.1 1.4e-30 105.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ38214.1 - 0.00038 20.5 0.0 0.00093 19.2 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ38214.1 - 0.014 14.6 0.1 0.026 13.8 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CBZ38214.1 - 0.051 13.9 0.4 0.45 10.8 0.4 2.4 1 1 0 1 1 1 0 AAA domain Dynein_light PF01221.18 CBZ38217.1 - 1.2e-13 51.2 0.3 1.6e-13 50.7 0.3 1.4 1 1 0 1 1 1 1 Dynein light chain type 1 IPK PF03770.16 CBZ38218.1 - 1.6e-19 70.5 0.0 1.5e-18 67.4 0.0 2.2 1 1 0 1 1 1 1 Inositol polyphosphate kinase Flavokinase PF01687.17 CBZ38220.1 - 1e-24 87.0 0.0 1.2e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase DUF1694 PF07997.11 CBZ38220.1 - 0.013 15.6 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) Pkinase PF00069.25 CBZ38221.1 - 3.3e-39 134.8 0.0 6.8e-39 133.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38221.1 - 2.1e-17 63.3 0.0 5.1e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ38221.1 - 2.3e-07 29.9 0.4 9.2e-07 28.0 0.4 2.1 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CBZ38221.1 - 0.00011 22.2 1.4 0.00057 19.9 0.1 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ38221.1 - 0.0083 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family RPN7 PF10602.9 CBZ38221.1 - 0.087 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 His_Phos_1 PF00300.22 CBZ38223.1 - 2.2e-10 40.5 0.0 2.5e-08 33.8 0.0 2.6 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) RRM_1 PF00076.22 CBZ38224.1 - 1.7e-07 30.9 0.0 5.3e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4781 PF16013.5 CBZ38224.1 - 2.7 6.7 4.3 4.4 6.0 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) Thymidylate_kin PF02223.17 CBZ38225.1 - 8.5e-36 123.4 0.0 1e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 CBZ38225.1 - 2.9e-06 27.5 0.0 8.3e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ38225.1 - 0.00018 22.0 0.0 0.0015 19.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CBZ38225.1 - 0.007 16.8 0.2 0.0093 16.4 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ38225.1 - 0.016 15.5 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CBZ38225.1 - 0.017 15.5 0.1 0.055 13.9 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CBZ38225.1 - 0.026 14.2 0.6 0.074 12.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 CBZ38225.1 - 0.072 13.1 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 CBZ38225.1 - 0.082 12.1 0.1 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Glyco_transf_28 PF03033.20 CBZ38225.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain AAA_28 PF13521.6 CBZ38225.1 - 0.16 12.2 0.9 0.43 10.8 0.9 1.8 1 1 0 1 1 1 0 AAA domain EF-hand_13 PF17958.1 CBZ38226.1 - 3.2e-17 62.1 0.0 6.6e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CBZ38226.1 - 1.7e-12 47.6 0.3 2e-11 44.2 0.0 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CBZ38226.1 - 0.013 15.3 2.5 0.019 14.8 0.1 2.6 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 CBZ38226.1 - 0.023 14.2 5.4 0.11 12.1 0.2 3.5 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 CBZ38226.1 - 0.054 13.4 4.9 4.3 7.3 1.1 2.9 2 1 0 2 2 2 0 EF-hand domain pair Popeye PF04831.13 CBZ38226.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Popeye protein conserved region EF-hand_5 PF13202.6 CBZ38226.1 - 0.17 11.4 0.5 0.58 9.8 0.0 2.2 2 0 0 2 2 2 0 EF hand PGM_PMM_II PF02879.16 CBZ38227.1 - 0.034 14.8 0.1 2.7 8.7 0.0 2.4 1 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Cys_Met_Meta_PP PF01053.20 CBZ38228.1 - 5.5e-130 433.3 0.1 6.3e-130 433.1 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CBZ38228.1 - 5e-08 32.6 2.1 1e-07 31.6 0.5 1.9 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CBZ38228.1 - 0.00011 21.3 0.1 0.00025 20.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CBZ38228.1 - 0.0017 17.7 0.8 0.0034 16.7 0.8 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 CBZ38228.1 - 0.025 13.3 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF3586 PF12131.8 CBZ38228.1 - 0.26 11.5 4.0 0.41 10.9 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) UPF0126 PF03458.13 CBZ38229.1 - 0.017 15.0 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 UPF0126 domain AAA PF00004.29 CBZ38230.1 - 1.6e-15 57.7 0.0 3.1e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CBZ38230.1 - 4.7e-13 49.4 0.0 1.2e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CBZ38230.1 - 1.8e-10 40.8 0.0 2.9e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CBZ38230.1 - 2.5e-10 40.6 0.0 5.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 CBZ38230.1 - 6.7e-07 29.2 0.0 2.5e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CBZ38230.1 - 2.1e-06 27.3 0.0 3.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CBZ38230.1 - 5.3e-06 26.9 0.0 2.9e-05 24.5 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ38230.1 - 1.3e-05 25.5 0.2 7.1e-05 23.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CBZ38230.1 - 1.5e-05 25.0 0.0 4e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CBZ38230.1 - 2.2e-05 24.5 0.0 3.8e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CBZ38230.1 - 2.3e-05 24.8 0.0 5.3e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBZ38230.1 - 0.00014 21.6 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CBZ38230.1 - 0.00018 21.0 0.0 0.0026 17.2 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_11 PF13086.6 CBZ38230.1 - 0.00037 20.4 0.1 0.0044 16.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_23 PF13476.6 CBZ38230.1 - 0.00042 20.9 0.0 0.00056 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CBZ38230.1 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RuvB_N PF05496.12 CBZ38230.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 CBZ38230.1 - 0.0015 18.8 0.0 0.0061 16.9 0.0 2.1 2 0 0 2 2 1 1 AAA C-terminal domain AAA_29 PF13555.6 CBZ38230.1 - 0.0021 17.7 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_3 PF07726.11 CBZ38230.1 - 0.0029 17.5 0.0 0.021 14.7 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 CBZ38230.1 - 0.0062 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CBZ38230.1 - 0.0072 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CBZ38230.1 - 0.017 14.8 0.0 0.076 12.7 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 CBZ38230.1 - 0.026 13.7 0.0 3 7.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ResIII PF04851.15 CBZ38230.1 - 0.03 14.3 0.0 1.1 9.2 0.0 2.1 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 CBZ38230.1 - 0.03 14.5 0.0 0.068 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CBZ38230.1 - 0.032 13.6 0.0 0.083 12.2 0.0 1.6 2 0 0 2 2 1 0 FtsK/SpoIIIE family DSBA PF01323.20 CBZ38230.1 - 0.032 14.0 0.1 0.074 12.8 0.0 1.6 2 0 0 2 2 2 0 DSBA-like thioredoxin domain DEAD PF00270.29 CBZ38230.1 - 0.056 13.2 0.2 0.38 10.5 0.0 2.0 1 1 1 2 2 2 0 DEAD/DEAH box helicase MeaB PF03308.16 CBZ38230.1 - 0.06 12.3 0.1 0.18 10.8 0.1 1.8 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2075 PF09848.9 CBZ38230.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 CBZ38230.1 - 0.07 12.9 0.0 4.1 7.1 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_2 PF07724.14 CBZ38230.1 - 0.11 12.6 0.0 0.61 10.2 0.0 2.1 2 1 1 3 3 2 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 CBZ38230.1 - 0.16 11.9 0.0 0.63 10.0 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pex19 PF04614.12 CBZ38231.1 - 2e-14 54.0 0.1 2e-14 54.0 0.1 3.5 1 1 1 3 3 3 2 Pex19 protein family PPR_2 PF13041.6 CBZ38231.1 - 0.056 13.7 0.3 0.19 12.0 0.3 1.9 1 0 0 1 1 1 0 PPR repeat family Ntox34 PF15606.6 CBZ38231.1 - 0.12 12.5 0.5 4 7.6 0.1 2.7 2 0 0 2 2 2 0 Bacterial toxin 34 Ribosomal_L31e PF01198.19 CBZ38233.1 - 1.6e-25 89.1 0.4 1.6e-25 89.1 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L31e Ribosomal_L31e PF01198.19 CBZ38234.1 - 1.6e-25 89.1 0.4 1.6e-25 89.1 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L31e WD40 PF00400.32 CBZ38235.1 - 0.0021 18.8 9.6 1.1 10.2 0.9 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Hira PF07569.11 CBZ38235.1 - 0.18 11.5 0.2 2.4 7.8 0.0 2.5 2 0 0 2 2 2 0 TUP1-like enhancer of split LRR_9 PF14580.6 CBZ38236.1 - 2.6e-11 43.3 0.6 7.7e-11 41.8 0.5 1.7 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CBZ38236.1 - 1.3e-08 35.0 0.4 0.00023 21.5 0.2 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ38236.1 - 1.2e-05 25.0 1.1 0.0041 16.9 0.1 2.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 CBZ38236.1 - 0.0012 18.7 1.2 21 5.5 0.0 4.0 3 0 0 3 3 3 3 Leucine Rich repeat TRAPP PF04051.16 CBZ38237.1 - 5.4e-25 87.8 0.0 6.4e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Mito_carr PF00153.27 CBZ38238.1 - 1.1e-52 175.9 0.3 1.1e-18 66.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein 6PGD PF00393.19 CBZ38239.1 - 1.2e-74 251.4 0.0 1.6e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CBZ38239.1 - 3e-47 160.7 0.1 4.5e-47 160.2 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CBZ38239.1 - 5.1e-06 26.6 0.2 8.5e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CBZ38239.1 - 2.2e-05 24.9 0.4 4.7e-05 23.9 0.4 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CBZ38239.1 - 2.9e-05 24.0 0.1 4.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 CBZ38239.1 - 0.00043 20.3 0.0 0.00085 19.3 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 CBZ38239.1 - 0.0026 17.1 0.3 0.0086 15.5 0.3 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CBZ38239.1 - 0.01 15.5 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 CBZ38239.1 - 0.081 12.1 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 CBZ38239.1 - 0.092 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain adh_short PF00106.25 CBZ38239.1 - 0.095 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase PGK PF00162.19 CBZ38239.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase TP_methylase PF00590.20 CBZ38240.1 - 4.9e-19 69.1 1.6 3.1e-18 66.5 0.1 2.6 2 2 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF3138 PF11336.8 CBZ38240.1 - 0.19 10.3 0.7 0.3 9.6 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2428 PF10350.9 CBZ38241.1 - 1.1e-35 123.2 0.6 4.5e-35 121.3 0.0 2.3 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) CLASP_N PF12348.8 CBZ38241.1 - 0.12 11.9 0.2 4.6 6.7 0.0 3.3 3 0 0 3 3 3 0 CLASP N terminal SesA PF17107.5 CBZ38241.1 - 0.18 12.0 0.7 0.93 9.7 0.7 2.2 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases HEAT PF02985.22 CBZ38241.1 - 0.64 10.4 14.0 24 5.5 0.4 6.3 6 0 0 6 6 6 0 HEAT repeat Sigma54_DBD PF04552.13 CBZ38242.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54, DNA binding domain PARP_regulatory PF01358.18 CBZ38243.1 - 6.9e-14 51.4 0.0 5e-09 35.5 0.0 2.6 2 1 0 2 2 2 2 Poly A polymerase regulatory subunit CDC50 PF03381.15 CBZ38245.1 - 2.4e-72 243.8 0.0 3.1e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Rep_fac-A_3 PF08661.11 CBZ38249.1 - 5.3e-07 29.9 0.0 1.1e-06 28.9 0.0 1.5 1 1 0 1 1 1 1 Replication factor A protein 3 Rad4 PF03835.15 CBZ38250.1 - 1.9e-21 76.3 0.1 4.3e-21 75.1 0.1 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CBZ38250.1 - 3.8e-15 56.1 0.0 1.4e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CBZ38250.1 - 4.7e-10 39.2 0.0 8.7e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CBZ38250.1 - 0.00035 21.5 4.4 0.01 16.8 0.9 3.6 2 1 0 2 2 2 1 Rad4 beta-hairpin domain 2 peroxidase PF00141.23 CBZ38251.1 - 5.7e-08 32.7 0.0 7.8e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 Peroxidase Acyl_transf_1 PF00698.21 CBZ38252.1 - 5.2e-21 75.5 0.0 2.1e-20 73.5 0.0 1.9 2 1 0 2 2 2 1 Acyl transferase domain SMC_N PF02463.19 CBZ38256.1 - 1.2e-57 194.8 0.0 2.3e-56 190.7 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CBZ38256.1 - 8.6e-25 87.3 0.0 4.6e-24 85.0 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CBZ38256.1 - 3.9e-14 53.1 0.0 1.8e-06 28.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CBZ38256.1 - 3e-08 34.4 54.8 0.00015 22.4 31.8 5.3 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 CBZ38256.1 - 3.7e-08 33.5 0.0 3.7e-08 33.5 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CBZ38256.1 - 1.9e-06 27.5 0.0 4.2e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CBZ38256.1 - 0.027 14.4 0.0 0.027 14.4 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase AAA PF00004.29 CBZ38256.1 - 0.052 14.0 0.2 1.5 9.2 0.1 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CBZ38256.1 - 0.19 12.3 0.0 0.19 12.3 0.0 5.9 4 2 0 4 4 4 0 ABC transporter AAA_22 PF13401.6 CBZ38256.1 - 3.2 8.0 11.2 9.4 6.5 0.0 5.1 3 2 0 3 3 3 0 AAA domain NIF PF03031.18 CBZ38257.1 - 2e-29 102.4 0.1 1.2e-15 57.7 0.0 2.5 1 1 1 2 2 2 2 NLI interacting factor-like phosphatase B12-binding_2 PF02607.17 CBZ38258.1 - 0.0065 16.9 0.0 9.6 6.7 0.0 3.3 3 0 0 3 3 3 2 B12 binding domain KH_1 PF00013.29 CBZ38259.1 - 0.00047 19.9 0.4 0.0012 18.6 0.4 1.7 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 CBZ38259.1 - 0.069 13.2 0.1 0.43 10.7 0.1 2.1 1 1 0 1 1 1 0 Krr1 KH1 domain DUF2497 PF10691.9 CBZ38260.1 - 0.0067 16.8 0.1 0.0067 16.8 0.1 3.6 4 0 0 4 4 4 1 Protein of unknown function (DUF2497) DUF4795 PF16043.5 CBZ38260.1 - 0.017 14.7 12.0 0.022 14.4 10.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) BLOC1_2 PF10046.9 CBZ38260.1 - 0.043 14.1 2.2 8.5 6.8 0.0 3.5 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF5098 PF17023.5 CBZ38260.1 - 0.06 12.3 0.9 0.082 11.9 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) Fib_alpha PF08702.10 CBZ38260.1 - 0.1 12.8 10.5 3.3 7.9 2.1 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.12 CBZ38260.1 - 0.12 12.4 3.8 0.78 9.8 0.3 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3584 PF12128.8 CBZ38260.1 - 0.13 9.7 19.5 0.21 9.1 19.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prominin PF05478.11 CBZ38260.1 - 0.72 7.7 6.4 1.5 6.7 6.4 1.5 1 1 0 1 1 1 0 Prominin DUF4407 PF14362.6 CBZ38260.1 - 0.94 8.8 17.9 4.4 6.6 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Apolipoprotein PF01442.18 CBZ38260.1 - 2 8.3 37.2 0.031 14.2 29.2 2.1 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 CBZ38260.1 - 2.3 8.5 11.2 72 3.7 0.0 4.9 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) zf-C4H2 PF10146.9 CBZ38260.1 - 3.1 8.0 13.5 0.14 12.5 0.4 2.9 1 1 1 2 2 2 0 Zinc finger-containing protein MIP-T3_C PF17749.1 CBZ38260.1 - 6.6 6.7 15.4 1.5 8.8 9.0 2.8 1 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region CRAL_TRIO PF00650.20 CBZ38261.1 - 8.3e-26 90.6 0.1 1.3e-25 90.0 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CBZ38261.1 - 4.7e-06 26.7 0.9 1.1e-05 25.5 0.9 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain FUSC_2 PF13515.6 CBZ38262.1 - 5.3e-09 36.3 4.3 1.2e-08 35.1 4.3 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 CBZ38262.1 - 0.0035 17.5 5.2 0.0035 17.5 5.2 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 1 MatE PF01554.18 CBZ38263.1 - 1.3e-32 112.6 26.3 3.9e-17 62.4 11.0 2.2 2 0 0 2 2 2 2 MatE XPG_I_2 PF12813.7 CBZ38264.1 - 1.2e-40 139.6 0.0 1.8e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 CBZ38264.1 - 3.3e-20 72.2 0.2 6.3e-20 71.3 0.2 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CBZ38264.1 - 8.1e-20 71.2 0.0 2e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 XPG N-terminal domain Methyltransf_23 PF13489.6 CBZ38265.1 - 1.1e-29 103.4 0.0 1.6e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF2252 PF10009.9 CBZ38265.1 - 0.00018 20.7 0.1 0.00027 20.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) Methyltransf_12 PF08242.12 CBZ38265.1 - 0.013 16.2 0.1 0.15 12.8 0.0 2.6 4 0 0 4 4 4 0 Methyltransferase domain Pro_isomerase PF00160.21 CBZ38266.1 - 1.3e-28 100.3 0.0 2.8e-28 99.2 0.0 1.4 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NifU_N PF01592.16 CBZ38267.1 - 6.4e-50 168.6 0.0 8.4e-50 168.2 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain MatE PF01554.18 CBZ38268.1 - 1.3e-33 115.9 32.3 7.4e-17 61.5 13.0 3.5 3 0 0 3 3 3 3 MatE TfuA PF07812.12 CBZ38268.1 - 0.037 13.8 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 TfuA-like protein NDUF_B7 PF05676.13 CBZ38272.1 - 5.2e-09 35.7 0.5 8.8e-09 35.0 0.5 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ribul_P_3_epim PF00834.19 CBZ38273.1 - 3.2e-49 167.0 0.0 3.7e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PEX11 PF05648.14 CBZ38274.1 - 8e-07 28.7 0.0 9.5e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEX11 PF05648.14 CBZ38275.1 - 3.3e-13 49.6 0.0 4.9e-13 49.1 0.0 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Vir_act_alpha_C PF10400.9 CBZ38276.1 - 0.0026 18.4 2.9 0.0048 17.5 2.9 1.3 1 0 0 1 1 1 1 Virulence activator alpha C-term DUF4190 PF13828.6 CBZ38276.1 - 6.7 6.6 8.8 0.32 10.8 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) APG6_N PF17675.1 CBZ38277.1 - 0.025 15.1 1.9 0.025 15.1 1.9 4.6 2 1 2 4 4 4 0 Apg6 coiled-coil region LPD23 PF18838.1 CBZ38277.1 - 1.1 9.0 4.1 0.7 9.7 0.1 2.7 3 0 0 3 3 3 0 Large polyvalent protein associated domain 23 HALZ PF02183.18 CBZ38277.1 - 1.5 9.1 6.1 29 5.0 0.3 3.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF3535 PF12054.8 CBZ38279.1 - 0.049 12.9 0.1 0.065 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) PhyH PF05721.13 CBZ38279.1 - 0.13 12.5 0.0 0.75 10.0 0.0 2.1 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Cullin PF00888.22 CBZ38280.1 - 4.9e-15 55.2 0.0 7.6e-15 54.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family Antibiotic_NAT PF02522.14 CBZ38280.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase U3snoRNP10 PF12397.8 CBZ38280.1 - 0.1 13.0 0.3 1.1 9.6 0.1 2.7 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 Ank_5 PF13857.6 CBZ38280.1 - 0.13 12.7 0.0 0.53 10.7 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 CBZ38280.1 - 0.13 12.9 0.1 3.1 8.6 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat Ribosomal_L27A PF00828.19 CBZ38281.1 - 4e-21 76.0 0.1 5.1e-21 75.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L14 PF00238.19 CBZ38283.1 - 4.3e-37 126.9 0.0 5.1e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PAS PF00989.25 CBZ38283.1 - 0.21 11.6 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 PAS fold Cep57_CLD_2 PF14197.6 CBZ38285.1 - 0.0047 17.0 3.1 0.0047 17.0 3.1 3.6 3 1 0 3 3 3 2 Centrosome localisation domain of PPC89 Trimer_CC PF08954.11 CBZ38285.1 - 0.0077 15.8 6.1 0.16 11.6 1.2 3.5 3 0 0 3 3 3 2 Trimerisation motif CENP-F_leu_zip PF10473.9 CBZ38285.1 - 0.082 12.9 13.8 0.49 10.4 2.1 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IFT20 PF14931.6 CBZ38285.1 - 0.48 10.6 13.2 0.58 10.3 1.6 2.6 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF4446 PF14584.6 CBZ38285.1 - 1.2 9.2 4.1 0.71 9.9 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) TSC22 PF01166.18 CBZ38285.1 - 1.7 9.0 7.3 9.2 6.7 1.5 3.8 3 1 0 3 3 3 0 TSC-22/dip/bun family DivIC PF04977.15 CBZ38285.1 - 1.9 8.3 16.2 3.8 7.4 0.1 4.5 3 2 1 4 4 4 0 Septum formation initiator SET PF00856.28 CBZ38286.1 - 8.1e-05 23.1 0.0 0.00013 22.4 0.0 1.3 1 0 0 1 1 1 1 SET domain Proteasome PF00227.26 CBZ38287.1 - 3.4e-47 160.4 0.4 4e-47 160.2 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CBZ38287.1 - 0.0026 17.1 2.5 0.0043 16.4 0.0 2.3 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Ribosomal_S17 PF00366.20 CBZ38288.1 - 9.4e-18 64.1 0.4 1.9e-17 63.1 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 Cpn60_TCP1 PF00118.24 CBZ38289.1 - 6.3e-157 523.1 2.1 7.9e-157 522.8 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NDK PF00334.19 CBZ38290.1 - 7.9e-31 106.9 0.0 1.2e-27 96.5 0.0 2.4 1 1 1 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 CBZ38290.1 - 1.1e-05 25.2 0.0 4.1e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 DUF1126 PH-like domain WD40 PF00400.32 CBZ38291.1 - 7.5e-30 102.5 14.9 1.7e-08 35.0 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.14 CBZ38291.1 - 1.3e-09 38.2 6.3 2.5e-09 37.3 6.3 1.4 1 0 0 1 1 1 1 Sof1-like domain ANAPC4_WD40 PF12894.7 CBZ38291.1 - 4.1e-05 23.8 0.0 0.17 12.2 0.0 4.5 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ38291.1 - 0.00014 21.0 0.2 0.98 8.3 0.0 3.2 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CBZ38291.1 - 0.0082 15.5 0.0 2.9 7.1 0.0 3.0 4 0 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 CBZ38291.1 - 0.75 8.4 6.0 16 3.9 0.1 3.6 3 2 1 4 4 4 0 Nucleoporin Nup120/160 EF-hand_7 PF13499.6 CBZ38292.1 - 2.6e-12 47.0 1.7 2.7e-06 27.7 0.7 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ38292.1 - 1.4e-08 33.7 4.6 4.5e-08 32.1 0.1 3.5 4 0 0 4 4 4 1 EF hand EF-hand_6 PF13405.6 CBZ38292.1 - 1.8e-08 33.7 0.1 3.2e-06 26.6 0.0 3.3 3 1 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 CBZ38292.1 - 2.1e-08 33.9 1.6 3e-05 23.8 0.4 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CBZ38292.1 - 0.00013 21.3 0.0 0.00013 21.3 0.0 2.6 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 CBZ38292.1 - 0.0051 17.1 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 CBZ38292.1 - 0.068 13.2 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 CBZ38292.1 - 0.098 13.0 0.0 5.4 7.4 0.0 2.2 1 1 1 2 2 2 0 EF-hand domain DUF1398 PF07166.11 CBZ38292.1 - 0.1 12.7 0.2 0.23 11.5 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1398) Rhodanese_C PF12368.8 CBZ38295.1 - 0.45 10.9 12.6 0.47 10.9 4.7 2.7 2 0 0 2 2 2 0 Rhodanase C-terminal SHIPPO-rpt PF07004.12 CBZ38296.1 - 2.4e-15 56.6 43.3 0.38 11.8 3.9 10.0 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat UNC-50 PF05216.13 CBZ38297.1 - 5.9e-46 156.8 9.3 7.4e-46 156.5 9.3 1.0 1 0 0 1 1 1 1 UNC-50 family INCENP_N PF12178.8 CBZ38298.1 - 0.00052 20.0 0.2 0.0011 19.0 0.2 1.5 1 0 0 1 1 1 1 Chromosome passenger complex (CPC) protein INCENP N terminal PROCN PF08083.11 CBZ38299.1 - 2.3e-192 639.2 3.7 6.6e-192 637.7 3.7 1.8 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CBZ38299.1 - 5e-91 304.4 0.0 8e-91 303.8 0.0 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CBZ38299.1 - 3.6e-69 231.8 0.1 8.1e-69 230.6 0.1 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 CBZ38299.1 - 7e-59 197.7 0.1 1.6e-58 196.6 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PRO8NT PF08082.11 CBZ38299.1 - 1.9e-58 196.7 0.0 5.7e-58 195.2 0.0 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain RRM_4 PF10598.9 CBZ38299.1 - 1.4e-36 124.7 0.1 4.3e-36 123.1 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 CBZ38299.1 - 1.4e-29 102.5 0.0 2.9e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain DUF5480 PF17576.2 CBZ38299.1 - 0.0086 16.0 0.3 0.019 14.9 0.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5480) Pkinase PF00069.25 CBZ38300.1 - 6.6e-20 71.6 0.1 7.8e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38300.1 - 2.2e-11 43.5 0.4 2.9e-11 43.1 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase zf-MIZ PF02891.20 CBZ38301.1 - 5e-20 71.0 1.3 1e-19 70.0 1.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CBZ38301.1 - 9.6e-05 22.1 0.1 0.00021 21.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Mito_carr PF00153.27 CBZ38303.1 - 4.3e-40 135.5 0.5 2.9e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein HECT PF00632.25 CBZ38304.1 - 1.8e-48 165.6 0.0 3.1e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 CBZ38304.1 - 2.8e-45 154.7 0.0 5.6e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38304.1 - 2.2e-29 102.5 0.0 1e-28 100.4 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase TPR_1 PF00515.28 CBZ38304.1 - 3.6e-13 48.7 2.3 5.4e-06 26.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ38304.1 - 5.8e-13 47.9 4.0 3.2e-05 23.7 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ38304.1 - 2.4e-11 42.9 1.6 0.0046 17.1 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38304.1 - 1.8e-09 37.1 0.7 1.2e-05 24.8 0.2 3.2 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 CBZ38304.1 - 6.2e-05 23.6 1.3 0.0003 21.4 0.3 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat Kinase-like PF14531.6 CBZ38304.1 - 6.8e-05 22.3 0.0 0.00019 20.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like TPR_7 PF13176.6 CBZ38304.1 - 0.00015 21.5 0.5 0.014 15.3 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38304.1 - 0.00017 22.1 5.0 0.51 11.3 0.0 4.2 3 0 0 3 3 2 2 Tetratricopeptide repeat APH PF01636.23 CBZ38304.1 - 0.00032 20.7 2.9 0.00033 20.6 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family TPR_19 PF14559.6 CBZ38304.1 - 0.0018 18.7 4.9 0.31 11.6 0.0 4.1 3 1 1 4 4 3 1 Tetratricopeptide repeat RIO1 PF01163.22 CBZ38304.1 - 0.0045 16.6 0.0 0.014 15.0 0.0 1.8 1 0 0 1 1 1 1 RIO1 family TPR_12 PF13424.6 CBZ38304.1 - 0.0061 16.8 0.2 0.36 11.2 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ38304.1 - 0.011 16.0 0.1 1.6 9.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_2c PF01411.19 CBZ38304.1 - 0.032 12.7 3.2 0.057 11.9 3.2 1.4 1 0 0 1 1 1 0 tRNA synthetases class II (A) EMP24_GP25L PF01105.24 CBZ38304.1 - 0.039 13.9 2.7 0.11 12.5 2.7 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD TPR_9 PF13371.6 CBZ38304.1 - 0.05 13.8 0.1 19 5.5 0.0 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ38304.1 - 0.067 13.8 0.2 3.1 8.6 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ38304.1 - 3.1 7.8 5.1 29 4.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 CBZ38305.1 - 1.7e-21 76.8 0.2 2e-21 76.5 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38305.1 - 9.6e-12 44.7 0.3 1.6e-11 44.0 0.2 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Hydrolase_4 PF12146.8 CBZ38306.1 - 9e-16 57.9 0.1 2.5e-10 40.0 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CBZ38306.1 - 3.5e-10 40.0 0.0 3.2e-07 30.3 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CBZ38306.1 - 4.3e-07 30.8 0.1 1e-06 29.5 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CBZ38306.1 - 5.5e-06 26.0 0.0 3.7e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CBZ38306.1 - 1.8e-05 24.7 0.0 0.048 13.4 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CBZ38306.1 - 4.2e-05 23.5 0.4 9.7e-05 22.3 0.4 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 CBZ38306.1 - 0.00021 20.1 0.1 0.0033 16.2 0.0 2.2 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 CBZ38306.1 - 0.00026 20.6 0.0 0.049 13.2 0.0 2.2 1 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 CBZ38306.1 - 0.00062 19.8 0.0 0.0014 18.6 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 CBZ38306.1 - 0.0034 17.0 0.0 1.5 8.4 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.12 CBZ38306.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.13 CBZ38306.1 - 0.033 13.8 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1100 PF06500.11 CBZ38306.1 - 0.036 12.9 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) UPF0227 PF05728.12 CBZ38306.1 - 0.054 13.4 0.0 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 CBZ38306.1 - 0.064 13.0 0.0 0.78 9.5 0.0 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 CBZ38306.1 - 0.19 11.4 0.1 0.66 9.6 0.1 1.9 1 1 0 1 1 1 0 PGAP1-like protein DEAD PF00270.29 CBZ38307.1 - 3.5e-38 131.1 0.0 1.3e-37 129.2 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ38307.1 - 3.2e-24 85.4 0.0 1.4e-23 83.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBZ38307.1 - 1.9e-13 50.4 0.0 5.6e-13 48.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CBZ38307.1 - 6.9e-05 22.9 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ PF00226.31 CBZ38308.1 - 5.5e-15 55.2 0.0 2.7e-09 37.0 0.0 2.5 2 0 0 2 2 2 2 DnaJ domain TORC_N PF12884.7 CBZ38308.1 - 2 9.3 8.7 0.1 13.4 2.5 2.2 3 0 0 3 3 3 0 Transducer of regulated CREB activity, N terminus Pkinase PF00069.25 CBZ38310.1 - 1.7e-39 135.8 0.0 2e-38 132.3 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38310.1 - 5.9e-21 74.9 0.0 3.7e-20 72.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ38310.1 - 2.3e-09 37.0 0.0 4.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CBZ38310.1 - 0.005 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-RING_4 PF14570.6 CBZ38310.1 - 8.8 6.2 17.3 15 5.4 17.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RIIa PF02197.17 CBZ38311.1 - 2.9e-11 42.8 0.0 2.3e-10 39.9 0.0 2.4 2 0 0 2 2 2 1 Regulatory subunit of type II PKA R-subunit EF-hand_6 PF13405.6 CBZ38311.1 - 5.4e-05 22.8 0.0 0.079 12.9 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CBZ38311.1 - 0.001 19.4 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ38311.1 - 0.091 12.4 0.0 3.7 7.3 0.0 2.8 2 0 0 2 2 2 0 EF hand TPR_2 PF07719.17 CBZ38312.1 - 3.1e-14 51.8 12.9 0.0023 17.9 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ38312.1 - 2.7e-12 47.0 13.8 2.3e-06 28.0 0.3 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38312.1 - 9.3e-10 38.5 19.5 0.00026 21.6 0.4 6.6 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38312.1 - 7.2e-09 35.8 20.7 0.00039 20.6 0.1 5.6 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ38312.1 - 2.5e-06 28.0 16.8 0.046 14.4 3.6 4.6 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ38312.1 - 2.7e-06 27.2 4.2 2.5 8.5 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ38312.1 - 7.5e-06 26.0 7.9 0.34 11.4 0.0 4.9 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ38312.1 - 9.6e-06 25.2 11.5 2.1 8.3 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ38312.1 - 1.5e-05 25.1 11.2 0.014 16.0 0.9 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 CBZ38312.1 - 5.8e-05 22.4 5.8 0.016 14.4 0.3 3.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ38312.1 - 8.3e-05 22.3 14.5 0.025 14.6 0.1 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ38312.1 - 0.00019 21.8 9.2 0.72 10.6 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat DUF218 PF02698.17 CBZ38312.1 - 0.0055 16.7 0.4 0.017 15.1 0.2 1.9 2 0 0 2 2 2 1 DUF218 domain TPR_11 PF13414.6 CBZ38312.1 - 0.0066 16.1 10.8 7.2 6.4 0.2 6.4 6 1 1 7 7 7 1 TPR repeat ANAPC3 PF12895.7 CBZ38312.1 - 0.033 14.4 9.3 0.69 10.2 1.1 3.4 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CBZ38312.1 - 0.073 13.0 20.2 5.6 7.0 0.6 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat HEAT_2 PF13646.6 CBZ38312.1 - 0.34 11.3 3.0 22 5.5 0.4 3.2 2 1 1 3 3 3 0 HEAT repeats Alkyl_sulf_dimr PF14863.6 CBZ38312.1 - 0.35 11.3 2.1 0.61 10.5 0.4 2.2 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation TPR_21 PF09976.9 CBZ38312.1 - 0.94 9.1 7.3 7.5 6.2 0.4 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat-like domain MIT PF04212.18 CBZ38312.1 - 1.7 8.7 9.5 1.4 9.0 0.5 3.7 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain SF3b10 PF07189.11 CBZ38314.1 - 9.6e-17 60.9 0.0 1e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) RecC_C PF17946.1 CBZ38314.1 - 0.12 12.2 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 RecC C-terminal domain SseB PF07179.12 CBZ38315.1 - 0.043 14.1 0.0 6.8 7.0 0.0 2.3 2 0 0 2 2 2 0 SseB protein N-terminal domain HD_3 PF13023.6 CBZ38316.1 - 4.6e-38 130.7 0.0 5.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CBZ38316.1 - 1.6e-11 44.3 0.0 2.5e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CBZ38316.1 - 3.7e-06 27.2 0.0 6.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 HD domain DUF1467 PF07330.12 CBZ38317.1 - 0.068 13.1 0.5 0.24 11.4 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) RRM_1 PF00076.22 CBZ38319.1 - 6.9e-73 240.4 0.1 4e-17 61.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CBZ38319.1 - 1.1e-24 86.3 0.1 2.1e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 CBZ38319.1 - 2.7e-09 36.8 0.0 0.073 12.9 0.0 3.9 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_3 PF08777.11 CBZ38319.1 - 5.1e-08 32.9 2.6 0.23 11.5 0.3 4.4 3 1 1 4 4 4 4 RNA binding motif Nup35_RRM_2 PF14605.6 CBZ38319.1 - 1.1e-07 31.8 0.1 0.023 14.7 0.0 3.9 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBZ38319.1 - 1.8e-05 24.8 0.0 0.19 11.8 0.0 5.0 5 2 0 5 5 5 1 RNA recognition motif RRM_5 PF13893.6 CBZ38319.1 - 9.3e-05 22.0 0.0 0.016 14.8 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBZ38319.1 - 0.1 12.7 0.6 7.8 6.7 0.0 3.4 3 0 0 3 3 3 0 Limkain b1 TB2_DP1_HVA22 PF03134.19 CBZ38320.1 - 0.02 14.8 0.9 0.049 13.6 0.9 1.6 1 0 0 1 1 1 0 TB2/DP1, HVA22 family GTP_EFTU PF00009.27 CBZ38321.1 - 2.8e-40 137.9 0.0 1.1e-38 132.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CBZ38321.1 - 2.1e-13 50.5 0.0 4.3e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CBZ38321.1 - 0.0021 18.1 0.0 0.011 15.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CBZ38321.1 - 0.03 14.7 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 FeoB_N PF02421.18 CBZ38321.1 - 0.064 12.8 0.1 0.34 10.4 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B HBS1_N PF08938.10 CBZ38321.1 - 8.1 6.8 9.2 46 4.4 9.2 2.1 1 1 0 1 1 1 0 HBS1 N-terminus DUF2009 PF09418.10 CBZ38322.1 - 7.5e-177 589.0 0.1 8.5e-177 588.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) RNA_pol_Rpc4 PF05132.14 CBZ38323.1 - 1.8e-06 28.5 0.0 4e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase III RPC4 BBS1 PF14779.6 CBZ38324.1 - 1e-81 274.1 0.0 3.6e-81 272.4 0.0 1.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 1 PHTB1_N PF14727.6 CBZ38324.1 - 0.0015 18.0 0.1 0.026 13.9 0.1 2.6 2 1 1 3 3 3 1 PTHB1 N-terminus BBS2_Mid PF14783.6 CBZ38324.1 - 0.0076 16.3 0.0 5.1 7.2 0.0 3.3 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Mcl1_mid PF12341.8 CBZ38324.1 - 0.099 12.0 0.3 5.6 6.2 0.1 2.6 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region VMA21 PF09446.10 CBZ38325.1 - 1.8e-05 24.7 7.1 2.7e-05 24.2 7.1 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF1218 PF06749.12 CBZ38325.1 - 0.042 14.4 1.0 0.1 13.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) Neurensin PF14927.6 CBZ38325.1 - 0.18 11.5 1.2 0.52 10.0 0.1 1.9 1 1 1 2 2 2 0 Neurensin Syja_N PF02383.18 CBZ38329.1 - 1.8e-23 83.4 0.0 5.5e-23 81.8 0.0 1.7 1 1 0 1 1 1 1 SacI homology domain PPR_2 PF13041.6 CBZ38330.1 - 0.07 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 PPR repeat family Methyltransf_23 PF13489.6 CBZ38331.1 - 1.5e-22 80.2 0.0 2.2e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ38331.1 - 1.6e-18 67.1 0.1 2.8e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ38331.1 - 3.9e-17 62.4 0.0 8.9e-17 61.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ38331.1 - 2e-15 57.3 0.2 5.5e-15 55.9 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ38331.1 - 6.3e-14 52.5 0.0 1.3e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBZ38331.1 - 6.2e-08 32.3 0.1 2e-07 30.6 0.1 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 CBZ38331.1 - 5.3e-07 29.8 0.0 8.2e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CBZ38331.1 - 6.1e-07 29.1 0.0 8.9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 CBZ38331.1 - 1.1e-05 25.2 0.3 5.1e-05 23.0 0.3 1.8 1 1 0 1 1 1 1 Nodulation protein S (NodS) Pox_MCEL PF03291.16 CBZ38331.1 - 2.2e-05 23.7 0.0 3.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme MTS PF05175.14 CBZ38331.1 - 5.5e-05 22.8 0.1 0.00011 21.8 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CBZ38331.1 - 0.0013 18.5 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 CBZ38331.1 - 0.0013 18.1 0.0 0.0026 17.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 CBZ38331.1 - 0.0085 15.7 0.4 0.2 11.3 0.1 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW TPMT PF05724.11 CBZ38331.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) TehB PF03848.14 CBZ38331.1 - 0.02 14.3 0.0 0.069 12.6 0.0 1.8 1 1 0 1 1 1 0 Tellurite resistance protein TehB DREV PF05219.12 CBZ38331.1 - 0.091 11.8 0.0 0.58 9.2 0.0 1.9 1 1 0 1 1 1 0 DREV methyltransferase FYVE PF01363.21 CBZ38332.1 - 6.3e-16 58.3 7.9 6.3e-16 58.3 7.9 2.6 2 1 0 2 2 2 1 FYVE zinc finger DUF5401 PF17380.2 CBZ38332.1 - 0.056 11.5 37.1 0.077 11.1 37.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) C1_1 PF00130.22 CBZ38332.1 - 0.057 13.3 8.7 0.14 12.1 3.7 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-C2H2_12 PF18112.1 CBZ38332.1 - 0.082 13.4 0.2 0.28 11.7 0.2 1.9 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain DUF3584 PF12128.8 CBZ38332.1 - 0.28 8.6 42.8 0.34 8.4 42.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myc_N PF01056.18 CBZ38332.1 - 1.2 9.0 15.7 1.5 8.6 15.7 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DZR PF12773.7 CBZ38332.1 - 1.6 8.9 18.0 0.42 10.7 9.2 3.1 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 CBZ38332.1 - 1.9 8.4 20.8 0.3 11.0 0.9 3.2 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4604 PF15377.6 CBZ38332.1 - 5 7.5 30.3 8.6 6.8 30.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Rhodanese_C PF12368.8 CBZ38332.1 - 6.1 7.3 15.0 5.3 7.5 9.2 2.5 1 1 1 2 2 2 0 Rhodanase C-terminal Borrelia_P83 PF05262.11 CBZ38332.1 - 7.8 4.9 37.7 10 4.4 37.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SRP-alpha_N PF04086.13 CBZ38332.1 - 7.9 6.3 29.9 11 5.8 29.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.10 CBZ38332.1 - 8.4 4.9 11.1 9.9 4.7 11.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAS-6_N PF16531.5 CBZ38334.1 - 2.4e-18 66.5 0.0 5.9e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal GIT_CC PF16559.5 CBZ38334.1 - 0.87 9.5 17.8 12 5.9 0.0 4.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_2 PF07716.15 CBZ38334.1 - 2.6 8.2 19.6 0.73 10.0 0.6 4.6 3 1 1 4 4 4 0 Basic region leucine zipper bZIP_1 PF00170.21 CBZ38334.1 - 4.9 7.3 29.3 0.38 10.9 6.4 4.6 5 0 0 5 5 5 0 bZIP transcription factor MCC-bdg_PDZ PF10506.9 CBZ38334.1 - 9.9 6.3 15.7 0.6 10.2 0.1 4.2 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4381 PF14316.6 CBZ38335.1 - 0.068 13.4 0.8 0.16 12.2 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3987 PF13148.6 CBZ38336.1 - 0.016 14.2 1.4 0.016 14.2 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) PepSY_TM PF03929.16 CBZ38336.1 - 0.03 14.0 0.9 0.055 13.1 0.9 1.4 1 0 0 1 1 1 0 PepSY-associated TM region DUF4633 PF15464.6 CBZ38336.1 - 0.21 11.8 6.4 0.2 11.8 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) DUF4179 PF13786.6 CBZ38337.1 - 0.061 13.8 1.0 4.7 7.7 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) PalH PF08733.10 CBZ38337.1 - 0.073 12.1 0.1 0.087 11.8 0.1 1.0 1 0 0 1 1 1 0 PalH/RIM21 Bac_export_2 PF01312.19 CBZ38337.1 - 0.16 11.2 1.3 0.18 10.9 1.3 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Hydrolase_6 PF13344.6 CBZ38338.1 - 1.8e-22 79.4 0.0 3.8e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CBZ38338.1 - 4.3e-14 52.3 0.0 1.1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4121 PF13497.6 CBZ38338.1 - 0.069 12.3 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) PIH1 PF08190.12 CBZ38339.1 - 2.6e-62 209.2 0.0 4.1e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 CBZ38339.1 - 4.7e-25 87.9 0.0 1.3e-24 86.5 0.0 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain DUF5495 PF17599.2 CBZ38340.1 - 0.14 12.5 0.1 0.93 9.8 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5495) PGAP1 PF07819.13 CBZ38341.1 - 5.4e-12 45.9 0.0 0.00014 21.7 0.0 2.9 2 1 0 2 2 2 2 PGAP1-like protein Abhydrolase_1 PF00561.20 CBZ38341.1 - 0.0052 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold MnmE_helical PF12631.7 CBZ38341.1 - 0.019 15.1 0.2 0.26 11.4 0.3 2.0 2 0 0 2 2 2 0 MnmE helical domain Hydrolase_4 PF12146.8 CBZ38341.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DNA_pol_B_exo1 PF03104.19 CBZ38342.1 - 4.3e-54 183.9 0.0 8.1e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DUF1744 PF08490.12 CBZ38342.1 - 2e-52 178.2 0.0 6.8e-51 173.1 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B PF00136.21 CBZ38342.1 - 1.1e-12 47.5 0.2 1.6e-10 40.4 0.2 3.0 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CBZ38342.1 - 6.1e-10 39.1 0.1 9.8e-08 31.9 0.0 2.5 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CBZ38342.1 - 9.6e-08 32.2 0.1 3.9e-07 30.2 0.1 2.1 1 1 0 1 1 1 1 RNase_H superfamily zf-DNA_Pol PF08996.10 CBZ38342.1 - 0.0049 16.6 2.8 0.014 15.2 2.8 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger zf-CHY PF05495.12 CBZ38342.1 - 0.27 11.7 3.0 1 9.9 3.0 2.1 1 1 0 1 1 1 0 CHY zinc finger zf-4CXXC_R1 PF10497.9 CBZ38342.1 - 3.7 7.8 6.2 2.2 8.5 1.5 2.6 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-3CxxC PF13695.6 CBZ38343.1 - 2e-07 31.4 1.5 2.3e-07 31.2 1.5 1.2 1 0 0 1 1 1 1 Zinc-binding domain zf-3CxxC_2 PF17180.4 CBZ38343.1 - 5.8e-05 23.7 5.7 0.0001 23.0 5.7 1.5 1 1 0 1 1 1 1 Zinc-binding domain zinc_ribbon_4 PF13717.6 CBZ38343.1 - 0.0021 18.0 0.4 0.0021 18.0 0.4 2.2 2 0 0 2 2 2 1 zinc-ribbon domain HypA PF01155.19 CBZ38343.1 - 0.043 13.8 0.3 0.057 13.4 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-dskA_traR PF01258.17 CBZ38343.1 - 0.55 10.2 3.9 3.9 7.5 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger OrfB_Zn_ribbon PF07282.11 CBZ38343.1 - 3.1 7.8 5.8 14 5.6 0.7 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain LisH PF08513.11 CBZ38344.1 - 0.024 14.6 0.2 0.035 14.1 0.2 1.3 1 0 0 1 1 1 0 LisH TPR_12 PF13424.6 CBZ38345.1 - 1.8e-07 31.3 9.8 0.0014 18.9 0.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat T2SSF PF00482.23 CBZ38345.1 - 0.12 12.4 0.6 0.79 9.7 0.2 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F TPR_8 PF13181.6 CBZ38345.1 - 1.7 9.0 5.5 63 4.2 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Snf7 PF03357.21 CBZ38346.1 - 6.7e-14 51.8 16.5 6.7e-14 51.8 16.5 1.7 1 1 1 2 2 2 1 Snf7 UCH PF00443.29 CBZ38346.1 - 0.17 11.4 1.6 0.3 10.5 1.6 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase AA_permease_2 PF13520.6 CBZ38347.1 - 1.5e-37 129.4 41.3 2e-37 129.1 41.3 1.1 1 0 0 1 1 1 1 Amino acid permease Mito_carr PF00153.27 CBZ38348.1 - 2.8e-17 62.4 0.6 4.2e-14 52.2 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein LSM PF01423.22 CBZ38351.1 - 2.1e-19 69.0 0.1 2.3e-19 68.8 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ38351.1 - 0.0001 22.4 0.0 0.00011 22.2 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CBZ38351.1 - 0.023 14.8 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain CS PF04969.16 CBZ38352.1 - 2e-09 38.3 0.0 2.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 CS domain ARL2_Bind_BART PF11527.8 CBZ38353.1 - 5e-06 26.6 1.0 7.6e-06 26.0 1.0 1.3 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART zf-ANAPC11 PF12861.7 CBZ38355.1 - 3.5e-29 100.7 10.3 3.8e-29 100.6 10.3 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CBZ38355.1 - 1.9e-18 66.5 12.6 2.5e-18 66.1 12.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CBZ38355.1 - 1.5e-06 27.9 19.0 1.3e-05 24.9 7.9 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ38355.1 - 1.8e-06 28.2 20.5 3.4e-05 24.1 19.4 2.5 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CBZ38355.1 - 2.1e-05 24.4 12.0 2.6e-05 24.1 11.2 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CBZ38355.1 - 3e-05 23.8 14.7 3.3e-05 23.6 13.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CBZ38355.1 - 0.00074 19.4 18.6 0.0034 17.3 17.2 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBZ38355.1 - 0.0015 18.4 17.7 0.069 13.0 10.8 2.6 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBZ38355.1 - 0.0032 17.1 4.9 0.0032 17.1 4.9 1.8 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CBZ38355.1 - 0.0091 15.7 15.3 0.32 10.8 15.3 2.5 1 1 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 CBZ38355.1 - 0.011 15.5 18.7 0.33 10.8 11.1 2.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CBZ38355.1 - 0.021 15.0 4.4 0.021 15.0 4.4 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HIT PF04438.16 CBZ38355.1 - 0.18 11.7 11.1 0.37 10.7 6.1 2.4 2 1 0 2 2 2 0 HIT zinc finger zf-Nse PF11789.8 CBZ38355.1 - 0.6 10.0 10.0 0.93 9.4 10.0 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 CBZ38355.1 - 3.7 7.5 14.8 57 3.7 14.8 2.5 1 1 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 CBZ38355.1 - 9.6 6.6 17.5 1.1e+02 3.2 17.6 2.5 1 1 0 1 1 1 0 RING-like domain FTCD_C PF04961.12 CBZ38356.1 - 0.25 11.1 2.7 1.6 8.5 0.2 2.5 2 1 0 2 2 2 0 Formiminotransferase-cyclodeaminase DUF962 PF06127.11 CBZ38357.1 - 1.3e-22 79.7 1.9 2.4e-22 78.8 1.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SET PF00856.28 CBZ38360.1 - 1.1e-33 117.1 0.0 2.4e-05 24.8 0.0 9.4 8 3 2 10 10 9 5 SET domain SAF PF08666.12 CBZ38360.1 - 0.0001 22.8 0.0 66 4.2 0.0 8.0 10 1 0 10 10 10 1 SAF domain zf-HC5HC2H PF13771.6 CBZ38361.1 - 6.6e-14 51.9 1.7 1.4e-13 50.9 1.7 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CBZ38361.1 - 5.4e-08 33.0 7.0 9.9e-08 32.1 7.0 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING-like PF08746.11 CBZ38361.1 - 9.9 6.6 8.0 0.5 10.7 1.6 2.1 2 0 0 2 2 2 0 RING-like domain 60KD_IMP PF02096.20 CBZ38363.1 - 0.00031 20.7 0.0 0.00055 19.9 0.0 1.5 1 1 0 1 1 1 1 60Kd inner membrane protein PS_Dcarbxylase PF02666.15 CBZ38364.1 - 4.1e-39 134.2 0.0 4.9e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Lebercilin PF15619.6 CBZ38365.1 - 3.3e-05 23.7 10.8 3.3e-05 23.7 10.8 5.0 5 2 1 6 6 6 2 Ciliary protein causing Leber congenital amaurosis disease NRBF2 PF08961.10 CBZ38365.1 - 0.0067 16.1 6.3 0.12 11.9 7.1 2.7 2 1 1 3 3 3 1 Nuclear receptor-binding factor 2, autophagy regulator Jnk-SapK_ap_N PF09744.9 CBZ38365.1 - 0.021 15.1 7.2 0.021 15.1 7.2 4.1 4 1 0 4 4 4 0 JNK_SAPK-associated protein-1 Ima1_N PF09779.9 CBZ38365.1 - 0.35 11.7 3.1 0.84 10.5 3.1 1.6 1 0 0 1 1 1 0 Ima1 N-terminal domain DUF3584 PF12128.8 CBZ38365.1 - 1.7 6.0 22.3 0.23 8.9 12.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Pox_A11 PF05061.13 CBZ38365.1 - 2.5 7.3 3.9 0.54 9.5 0.4 1.8 2 0 0 2 2 2 0 Poxvirus A11 Protein GAS PF13851.6 CBZ38365.1 - 7.2 5.9 28.6 0.9 8.9 1.0 4.9 5 0 0 5 5 5 0 Growth-arrest specific micro-tubule binding Pkinase PF00069.25 CBZ38367.1 - 9.7e-11 41.5 0.0 2.3e-09 37.0 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38367.1 - 0.0033 16.7 0.0 0.0074 15.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.31 CBZ38368.1 - 9.8e-14 51.2 0.1 1.9e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain PSD1 PF07587.11 CBZ38368.1 - 0.079 12.4 0.0 3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1553) Cgr1 PF03879.14 CBZ38369.1 - 1.7e-06 28.3 23.7 2.2e-06 28.0 23.7 1.2 1 0 0 1 1 1 1 Cgr1 family Med8 PF10232.9 CBZ38369.1 - 0.015 14.9 6.0 0.017 14.7 6.0 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 EcoRII-C PF09019.11 CBZ38369.1 - 0.025 14.7 3.0 0.038 14.1 2.8 1.4 1 1 0 1 1 1 0 EcoRII C terminal FAM178 PF14816.6 CBZ38369.1 - 0.049 12.6 5.1 0.054 12.5 5.1 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 LPP20 PF02169.16 CBZ38369.1 - 0.071 13.5 2.9 0.086 13.2 2.9 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein MGS PF02142.22 CBZ38369.1 - 0.12 12.6 0.8 0.18 12.0 0.8 1.3 1 0 0 1 1 1 0 MGS-like domain AAA_11 PF13086.6 CBZ38369.1 - 0.71 9.6 12.2 0.74 9.5 12.2 1.0 1 0 0 1 1 1 0 AAA domain DUF2756 PF10956.8 CBZ38369.1 - 4.5 7.8 9.4 8.8 6.9 9.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2756) DSPc PF00782.20 CBZ38370.1 - 4.2e-17 62.2 0.0 6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CBZ38370.1 - 0.036 13.6 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.12 CBZ38370.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) zf-SNAP50_C PF12251.8 CBZ38371.1 - 9.3e-38 129.9 0.1 1.3e-37 129.4 0.1 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Katanin_con80 PF13925.6 CBZ38372.1 - 9.3e-26 90.8 0.0 1.3e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 CBZ38372.1 - 2.7e-25 88.1 7.8 4.7e-06 27.2 0.4 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ38372.1 - 1.6e-13 50.8 0.0 2.3e-06 27.8 0.0 3.8 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CBZ38372.1 - 0.0058 16.5 0.0 6 6.7 0.0 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CBZ38372.1 - 0.01 15.2 0.0 0.094 12.0 0.0 2.2 1 1 1 2 2 2 0 WD40-like domain Ge1_WD40 PF16529.5 CBZ38372.1 - 0.1 11.5 0.0 0.4 9.6 0.0 1.9 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3450 PF11932.8 CBZ38373.1 - 0.0024 17.2 2.0 0.0028 17.0 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Med4 PF10018.9 CBZ38373.1 - 0.023 14.4 0.2 0.028 14.1 0.2 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Ntox6 PF15544.6 CBZ38373.1 - 0.05 13.2 0.1 0.052 13.1 0.1 1.1 1 0 0 1 1 1 0 Bacterial toxin 6 Wtap PF17098.5 CBZ38373.1 - 0.077 12.9 1.6 0.092 12.7 1.6 1.1 1 0 0 1 1 1 0 WTAP/Mum2p family NEMO PF11577.8 CBZ38373.1 - 0.14 12.2 5.6 6.1 6.9 0.4 2.2 1 1 1 2 2 2 0 NF-kappa-B essential modulator NEMO HBS1_N PF08938.10 CBZ38373.1 - 0.15 12.4 1.6 0.68 10.3 1.6 2.0 1 1 0 1 1 1 0 HBS1 N-terminus ParcG PF10274.9 CBZ38374.1 - 7.2e-76 254.4 0.0 8.9e-76 254.1 0.0 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein Kinesin PF00225.23 CBZ38375.1 - 3.3e-56 190.6 0.9 1.1e-55 188.9 0.9 1.7 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CBZ38375.1 - 2.8e-08 33.8 0.0 5.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF87 PF01935.17 CBZ38375.1 - 0.074 13.1 0.1 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_16 PF13191.6 CBZ38375.1 - 0.096 13.1 0.4 0.23 11.8 0.3 1.6 1 1 0 1 1 1 0 AAA ATPase domain PhoH PF02562.16 CBZ38375.1 - 0.098 12.1 0.3 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 CBZ38375.1 - 0.25 11.6 0.8 0.59 10.4 0.8 1.8 1 1 0 1 1 1 0 AAA domain HSP70 PF00012.20 CBZ38376.1 - 3.3e-60 203.9 2.4 5e-59 200.0 2.4 2.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CBZ38376.1 - 0.00062 18.7 0.0 0.0067 15.3 0.0 2.5 3 0 0 3 3 3 1 MreB/Mbl protein GCV_H PF01597.19 CBZ38377.1 - 1.6e-36 124.9 0.7 1.7e-36 124.8 0.7 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CBZ38377.1 - 2e-07 30.8 0.3 3.3e-07 30.0 0.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme PTS_EIIA_1 PF00358.20 CBZ38377.1 - 9.5e-05 22.2 0.1 0.00011 21.9 0.1 1.2 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 RnfC_N PF13375.6 CBZ38377.1 - 0.00011 22.1 0.2 0.00014 21.7 0.2 1.2 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Peptidase_M23 PF01551.22 CBZ38377.1 - 0.026 14.7 0.5 1.9 8.7 0.1 2.2 1 1 1 2 2 2 0 Peptidase family M23 MS_channel PF00924.18 CBZ38377.1 - 0.03 13.9 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel Gp_dh_N PF00044.24 CBZ38379.1 - 2e-18 66.6 0.0 3.4e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Gp_dh_C PF02800.20 CBZ38379.1 - 9.6e-12 44.8 0.1 1.8e-11 43.9 0.0 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain ADH_zinc_N PF00107.26 CBZ38379.1 - 0.063 13.3 0.2 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Pho88 PF10032.9 CBZ38380.1 - 0.019 14.2 1.5 0.041 13.2 1.5 1.5 1 0 0 1 1 1 0 Phosphate transport (Pho88) Pro_isomerase PF00160.21 CBZ38381.1 - 3e-46 157.6 0.1 5.5e-46 156.7 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CBZ38381.1 - 1.5e-09 37.2 3.9 0.0004 20.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ38381.1 - 3.7e-08 32.8 2.9 0.00025 20.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38381.1 - 1e-05 25.1 3.2 0.098 12.4 0.2 3.5 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 CBZ38381.1 - 2.5e-05 24.7 4.7 0.01 16.4 0.2 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ38381.1 - 4.8e-05 23.7 0.8 0.31 11.8 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ38381.1 - 0.00017 21.7 0.3 0.00037 20.6 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38381.1 - 0.0017 19.0 0.3 0.027 15.2 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ38381.1 - 0.004 17.2 2.0 1.2 9.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ38381.1 - 0.011 16.4 4.2 0.037 14.7 1.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38381.1 - 0.014 15.7 4.4 0.84 10.0 1.2 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF1586 PF07625.11 CBZ38381.1 - 0.025 14.6 0.3 0.064 13.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1586) TPR_17 PF13431.6 CBZ38381.1 - 0.036 14.4 0.1 0.19 12.2 0.0 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat MIT PF04212.18 CBZ38381.1 - 0.055 13.5 0.5 0.055 13.5 0.5 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 CBZ38381.1 - 0.056 13.7 3.4 0.75 10.1 2.4 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Sigma70_r3 PF04539.16 CBZ38381.1 - 0.25 11.5 1.1 1.2 9.2 0.4 2.2 2 0 0 2 2 2 0 Sigma-70 region 3 SCAMP PF04144.13 CBZ38383.1 - 6.9e-39 133.9 13.6 8.6e-39 133.6 13.6 1.0 1 0 0 1 1 1 1 SCAMP family DUF1129 PF06570.11 CBZ38383.1 - 0.03 13.8 0.3 0.035 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) A_deaminase PF00962.22 CBZ38384.1 - 2.7e-120 401.7 0.0 9.8e-88 294.6 0.0 3.0 3 0 0 3 3 3 3 Adenosine/AMP deaminase BRCT_2 PF16589.5 CBZ38385.1 - 1.1e-07 32.1 0.0 6.2e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CBZ38385.1 - 1.1e-05 25.7 0.0 0.26 11.7 0.0 2.7 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 CBZ38385.1 - 0.035 14.2 0.1 13 5.9 0.0 2.7 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CBZ38385.1 - 0.083 13.2 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain His_Phos_1 PF00300.22 CBZ38386.1 - 8.9e-12 45.1 0.0 0.00014 21.7 0.0 3.3 3 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Radical_SAM PF04055.21 CBZ38387.1 - 0.0028 18.0 0.0 0.018 15.5 0.0 2.2 1 1 1 2 2 2 1 Radical SAM superfamily Proteasome PF00227.26 CBZ38389.1 - 4.5e-39 133.9 0.1 6.6e-39 133.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ38389.1 - 1.5e-11 43.8 0.2 1.5e-11 43.8 0.2 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2358 PF10184.9 CBZ38390.1 - 0.077 13.3 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) RNase_3_N PF18497.1 CBZ38391.1 - 0.04 14.1 3.5 0.23 11.7 1.4 3.6 2 1 0 2 2 2 0 Ribonuclease III N-terminal domain PG_binding_3 PF09374.10 CBZ38391.1 - 6 7.2 7.7 38 4.7 2.4 4.6 2 1 0 2 2 2 0 Predicted Peptidoglycan domain TPR_1 PF00515.28 CBZ38392.1 - 1.5e-15 56.2 12.5 2.6e-06 27.0 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ38392.1 - 4.8e-11 41.9 23.3 3.2e-05 23.7 0.5 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38392.1 - 2e-09 37.0 11.5 1.4e-08 34.3 2.8 2.7 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.6 CBZ38392.1 - 1e-07 31.6 10.4 0.027 14.7 1.9 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat UPF0121 PF03661.13 CBZ38392.1 - 2.2e-06 27.2 11.2 4e-06 26.4 11.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) TPR_16 PF13432.6 CBZ38392.1 - 4.6e-06 27.2 2.2 4.6e-06 27.2 2.2 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ38392.1 - 1.1e-05 25.4 1.1 1.1e-05 25.4 1.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38392.1 - 1.6e-05 25.1 8.9 0.00023 21.4 3.2 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ38392.1 - 0.00026 20.8 11.3 0.043 13.7 2.4 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ38392.1 - 0.00027 20.7 2.0 1.1 9.4 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ38392.1 - 0.087 13.1 6.2 0.19 12.0 6.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CBZ38392.1 - 0.36 11.8 0.1 0.36 11.8 0.1 4.7 3 1 2 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ38392.1 - 0.56 10.8 11.4 0.16 12.5 1.1 3.1 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 CBZ38392.1 - 0.8 9.8 8.0 7.4 6.7 2.3 3.8 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 CBZ38392.1 - 3.4 8.1 8.7 20 5.6 0.4 3.0 1 1 0 2 2 2 0 Bacterial transcriptional activator domain COX14 PF14880.6 CBZ38392.1 - 7.3 6.5 9.3 0.34 10.8 1.8 2.7 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Rad51 PF08423.11 CBZ38393.1 - 5.8e-124 412.4 0.0 7e-124 412.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CBZ38393.1 - 5.6e-14 52.2 0.2 7e-14 51.9 0.2 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CBZ38393.1 - 9.5e-07 28.4 0.1 1.7e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 CBZ38393.1 - 1.4e-05 24.8 0.0 2.6e-05 23.9 0.0 1.4 2 0 0 2 2 2 1 AAA domain HHH_5 PF14520.6 CBZ38393.1 - 0.018 15.6 0.4 0.064 13.9 0.4 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain DnaB_C PF03796.15 CBZ38393.1 - 0.065 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 CBZ38393.1 - 0.091 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 CBZ38395.1 - 2.1e-57 193.8 0.0 3.3e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CBZ38395.1 - 7.2e-15 55.2 0.0 1.9e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 CBZ38395.1 - 4.4e-12 45.9 0.9 8.7e-12 45.0 0.9 1.4 1 0 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 CBZ38395.1 - 0.00014 21.8 0.0 0.0014 18.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CBZ38395.1 - 0.00059 19.3 0.0 0.033 13.6 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CBZ38395.1 - 0.014 15.3 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TTL PF03133.15 CBZ38396.1 - 4.7e-76 255.7 0.0 7.5e-76 255.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CBZ38396.1 - 0.0015 17.8 0.1 0.015 14.6 0.0 2.4 2 1 1 3 3 3 1 YheC/D like ATP-grasp DUF4303 PF14136.6 CBZ38396.1 - 0.13 12.0 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) ATPgrasp_ST PF14397.6 CBZ38396.1 - 0.21 10.8 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Med30 PF11315.8 CBZ38397.1 - 0.1 12.8 3.0 0.096 12.9 1.5 1.7 1 1 0 1 1 1 0 Mediator complex subunit 30 Neur_chan_memb PF02932.16 CBZ38397.1 - 0.87 9.6 3.1 1.3 9.0 3.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FoP_duplication PF13865.6 CBZ38397.1 - 4.1 8.0 12.2 1 9.9 4.2 2.9 2 1 1 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 zf-CCCH PF00642.24 CBZ38398.1 - 0.0012 18.7 4.6 0.0021 17.9 4.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ38398.1 - 0.0012 18.5 4.5 0.0019 18.0 4.5 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger SUIM_assoc PF16619.5 CBZ38398.1 - 0.015 15.4 0.0 0.015 15.4 0.0 4.7 3 2 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 zf-CCCH_2 PF14608.6 CBZ38398.1 - 0.04 14.4 3.9 0.065 13.7 3.9 1.3 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 CBZ38398.1 - 0.33 11.1 6.0 0.58 10.3 6.0 1.4 1 0 0 1 1 1 0 Zinc finger domain PAP2_C PF14360.6 CBZ38401.1 - 2.7e-20 72.7 7.5 2.7e-20 72.7 7.5 2.6 3 0 0 3 3 3 1 PAP2 superfamily C-terminal PAP2 PF01569.21 CBZ38401.1 - 0.67 9.7 12.1 0.34 10.7 8.0 2.3 2 1 0 2 2 2 0 PAP2 superfamily PSP1 PF04468.12 CBZ38402.1 - 6.1e-19 68.1 1.0 9.7e-19 67.4 1.0 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PE_PPE_C PF12484.8 CBZ38402.1 - 0.0096 16.8 5.1 0.023 15.6 5.1 1.6 1 0 0 1 1 1 1 Polymorphic PE/PPE proteins C terminal Leptin PF02024.15 CBZ38402.1 - 0.078 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Leptin DAGK_acc PF00609.19 CBZ38404.1 - 4.1e-37 128.0 0.0 5.7e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 CBZ38404.1 - 7.7e-12 44.9 0.0 1.2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 CBZ38404.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Aa_trans PF01490.18 CBZ38405.1 - 2e-53 181.6 32.5 2.3e-53 181.4 32.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ38405.1 - 9e-07 28.3 18.6 9e-07 28.3 18.6 2.1 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family HECT PF00632.25 CBZ38406.1 - 6.4e-37 127.7 0.3 1.4e-36 126.5 0.3 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBZ38406.1 - 1.7e-18 66.9 0.0 1.1e-07 31.9 0.0 5.0 5 0 0 5 5 5 3 SPRY domain Exo70 PF03081.15 CBZ38407.1 - 0.0012 17.9 1.4 0.0071 15.4 1.4 1.9 1 1 0 1 1 1 1 Exo70 exocyst complex subunit Glycoprotein_B PF00606.18 CBZ38408.1 - 0.064 12.7 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain Methyltransf_11 PF08241.12 CBZ38409.1 - 1.7e-05 25.4 0.0 0.00075 20.1 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ38409.1 - 0.00018 21.4 0.0 0.00024 21.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ38409.1 - 0.0002 22.0 0.0 0.00041 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ38409.1 - 0.00075 19.3 0.0 0.082 12.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ38409.1 - 0.0029 18.3 0.0 0.13 13.0 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase domain Pex16 PF08610.10 CBZ38409.1 - 0.019 14.1 0.0 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 Peroxisomal membrane protein (Pex16) BT1 PF03092.16 CBZ38410.1 - 3.6e-223 741.5 10.9 4.2e-223 741.3 10.9 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.16 CBZ38410.1 - 2.6e-05 23.3 13.8 2.6e-05 23.3 13.8 3.7 2 1 1 3 3 3 2 Major Facilitator Superfamily AAA_28 PF13521.6 CBZ38411.1 - 0.0011 19.2 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ38411.1 - 0.0032 18.0 0.0 0.0074 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CBZ38411.1 - 0.0061 16.5 0.0 0.023 14.6 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 CBZ38411.1 - 0.0096 16.3 0.0 0.014 15.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 CBZ38411.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CBZ38411.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBZ38411.1 - 0.018 14.4 0.0 0.032 13.5 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin AAA PF00004.29 CBZ38411.1 - 0.047 14.1 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CBZ38411.1 - 0.092 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 CBZ38411.1 - 0.16 12.1 0.0 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CBZ38412.1 - 0.00046 20.3 0.0 0.00081 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CBZ38412.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Peptidase_C92 PF05708.12 CBZ38413.1 - 0.13 12.3 0.1 0.89 9.6 0.0 2.1 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Pkinase PF00069.25 CBZ38414.1 - 7.3e-57 192.7 0.0 1.1e-56 192.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38414.1 - 2e-35 122.3 0.0 3.1e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CBZ38414.1 - 1.3e-11 44.9 0.0 5.8e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 CBZ38414.1 - 8.8e-08 31.8 0.0 1.6e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 CBZ38414.1 - 0.028 14.9 0.5 0.12 12.9 0.5 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.7 CBZ38414.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology zf-CCCH PF00642.24 CBZ38415.1 - 5.4e-05 23.0 0.3 5.4e-05 23.0 0.3 2.4 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CBZ38415.1 - 0.00013 22.2 1.2 0.00027 21.1 1.2 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 CBZ38415.1 - 0.00027 20.9 8.1 0.0039 17.2 0.8 2.7 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 CBZ38415.1 - 0.71 10.4 11.9 2.8 8.5 3.2 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 CBZ38415.1 - 0.92 9.4 7.1 1.6 8.6 0.2 3.0 2 1 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 CBZ38415.1 - 1.5 9.6 5.6 7 7.4 0.9 2.3 1 1 1 2 2 2 0 Torus domain MMR_HSR1 PF01926.23 CBZ38416.1 - 1.2e-12 48.0 0.0 1.7e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CBZ38416.1 - 1.1e-06 28.7 0.0 9.2e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CBZ38416.1 - 0.0041 17.4 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 CBZ38416.1 - 0.021 14.4 0.1 0.049 13.2 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.23 CBZ38416.1 - 0.047 13.7 0.9 3.5 7.7 0.0 2.8 2 1 1 3 3 3 0 Dynamin family Septin PF00735.18 CBZ38416.1 - 0.13 11.6 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 CBZ38416.1 - 0.14 12.5 0.0 0.44 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DUF4407 PF14362.6 CBZ38417.1 - 0.0049 16.3 9.2 0.0049 16.3 9.2 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) V-SNARE PF05008.15 CBZ38417.1 - 0.044 14.2 3.3 0.067 13.6 1.3 2.5 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus CCDC92 PF14916.6 CBZ38417.1 - 0.072 12.9 2.9 0.12 12.1 0.2 2.7 3 0 0 3 3 3 0 Coiled-coil domain of unknown function CEP63 PF17045.5 CBZ38417.1 - 0.12 12.2 15.5 0.45 10.4 2.5 3.8 3 1 0 3 3 3 0 Centrosomal protein of 63 kDa JIP_LZII PF16471.5 CBZ38417.1 - 0.35 11.1 5.2 0.73 10.0 0.3 3.3 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II RRP36 PF06102.12 CBZ38417.1 - 0.7 9.8 3.2 0.33 10.9 0.8 1.7 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 DUF4201 PF13870.6 CBZ38417.1 - 0.99 9.1 12.2 0.038 13.7 4.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) DUF3138 PF11336.8 CBZ38417.1 - 1.8 7.1 5.6 2.6 6.5 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CLZ PF16526.5 CBZ38417.1 - 2.7 8.4 12.6 15 6.0 2.4 3.7 2 2 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Methyltransf_4 PF02390.17 CBZ38418.1 - 1.8e-36 125.2 0.0 2.4e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 CBZ38418.1 - 3.7e-05 23.6 0.0 0.00034 20.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ38418.1 - 0.0004 21.0 0.0 0.0024 18.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ38418.1 - 0.0047 17.6 0.0 0.016 15.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Transpos_assoc PF13963.6 CBZ38418.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Transposase-associated domain ALG11_N PF15924.5 CBZ38420.1 - 1.4e-59 201.7 0.0 1.9e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CBZ38420.1 - 3e-21 75.7 0.0 4.4e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CBZ38420.1 - 4.3e-11 43.4 0.3 7.5e-11 42.6 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CBZ38420.1 - 0.0033 17.8 0.0 0.0081 16.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 HALZ PF02183.18 CBZ38421.1 - 4.5e-06 26.8 1.1 7.9e-06 26.0 1.1 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper Fungal_TACC PF12709.7 CBZ38421.1 - 0.0028 18.1 0.3 0.0037 17.7 0.2 1.4 1 1 0 1 1 1 1 Fungal Transforming acidic coiled-coil (TACC) proteins Prp19 PF08606.11 CBZ38421.1 - 0.0055 16.7 0.4 0.2 11.7 0.1 2.1 2 0 0 2 2 2 1 Prp19/Pso4-like DUF1640 PF07798.11 CBZ38421.1 - 0.0074 16.4 0.2 0.0087 16.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DivIC PF04977.15 CBZ38421.1 - 0.016 15.0 2.7 0.019 14.8 0.4 1.9 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 CBZ38421.1 - 0.052 14.0 0.6 0.052 14.0 0.6 1.8 2 1 0 2 2 2 0 Cell division protein ZapB Dpy-30 PF05186.13 CBZ38421.1 - 0.062 13.0 0.2 0.16 11.7 0.2 1.7 1 1 0 1 1 1 0 Dpy-30 motif bZIP_2 PF07716.15 CBZ38421.1 - 0.079 13.1 1.0 0.079 13.1 1.0 1.8 2 0 0 2 2 2 0 Basic region leucine zipper WD40 PF00400.32 CBZ38422.1 - 2.1e-09 37.8 5.6 0.0023 18.7 0.1 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat MMR_HSR1_Xtn PF16897.5 CBZ38426.1 - 3.9e-37 126.5 0.8 7.3e-37 125.6 0.8 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CBZ38426.1 - 7e-23 80.5 0.0 1.5e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CBZ38426.1 - 7.3e-19 67.9 0.0 1.7e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ38426.1 - 8.7e-10 38.3 0.0 1.6e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CBZ38426.1 - 0.00056 20.0 0.2 0.18 11.8 0.0 2.5 1 1 0 2 2 2 2 Dynamin family Roc PF08477.13 CBZ38426.1 - 0.011 15.9 0.1 0.66 10.2 0.0 3.1 1 1 2 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CBZ38426.1 - 0.067 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 AIG1 family SAC3_GANP PF03399.16 CBZ38427.1 - 1.8e-11 44.0 1.2 8.4e-10 38.5 1.2 2.2 1 1 0 1 1 1 1 SAC3/GANP family NTP_transf_3 PF12804.7 CBZ38427.1 - 0.12 12.7 0.2 0.22 11.9 0.2 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain FMN_dh PF01070.18 CBZ38428.1 - 8.4e-31 107.3 0.1 1.6e-19 70.1 0.2 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 CBZ38428.1 - 5.5e-07 28.9 0.7 0.0012 17.9 0.2 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CBZ38428.1 - 4.4e-05 22.8 1.3 0.00026 20.2 1.3 2.0 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CBZ38428.1 - 0.025 14.0 0.3 0.048 13.0 0.3 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 CBZ38428.1 - 0.42 10.0 2.3 0.61 9.5 0.1 2.1 2 1 1 3 3 3 0 Histidine biosynthesis protein Ank_2 PF12796.7 CBZ38429.1 - 5e-09 36.6 0.0 1.6e-08 35.0 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Dynein_heavy PF03028.15 CBZ38429.1 - 7.1e-09 35.8 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Ank_4 PF13637.6 CBZ38429.1 - 6e-07 29.9 0.0 0.032 14.8 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CBZ38429.1 - 2e-05 24.8 0.0 0.00057 20.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CBZ38429.1 - 0.0016 18.7 0.0 0.067 13.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Aa_trans PF01490.18 CBZ38430.1 - 1.5e-55 188.6 32.7 1.7e-55 188.4 32.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DHHC PF01529.20 CBZ38430.1 - 0.022 14.9 3.7 0.022 14.9 3.7 3.9 2 2 3 5 5 5 0 DHHC palmitoyltransferase MscL PF01741.18 CBZ38430.1 - 1.2 9.5 4.5 0.74 10.1 0.4 2.6 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL Pkinase PF00069.25 CBZ38431.1 - 1.3e-67 227.9 0.0 1.6e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38431.1 - 1.1e-29 103.5 0.0 3e-29 102.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ38431.1 - 6.5e-06 25.7 0.1 0.00043 19.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CBZ38431.1 - 0.012 15.2 0.1 0.071 12.7 0.0 1.9 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CBZ38431.1 - 0.028 14.3 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CBZ38431.1 - 0.044 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 CBZ38431.1 - 0.061 12.7 0.2 0.13 11.6 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_ligase_A_N PF04675.14 CBZ38432.1 - 0.052 13.9 0.2 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 DNA ligase N terminus RRM_1 PF00076.22 CBZ38434.1 - 1.3e-78 258.8 4.8 1.4e-20 72.9 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CBZ38434.1 - 1.6e-21 76.3 0.4 1.4e-20 73.3 0.1 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CBZ38434.1 - 3.7e-09 36.3 0.2 0.00065 19.3 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CBZ38434.1 - 3.1e-06 27.2 1.3 0.66 10.1 0.3 4.3 4 0 0 4 4 4 1 RNA binding motif DUF4523 PF15023.6 CBZ38434.1 - 9.7e-06 25.5 0.1 0.05 13.4 0.1 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.6 CBZ38434.1 - 2.3e-05 24.3 0.6 1.1 9.3 0.1 4.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CBZ38434.1 - 5.7e-05 23.2 0.9 0.14 12.3 0.1 3.7 4 2 0 4 4 4 2 RNA recognition motif Pkinase_C PF00433.24 CBZ38434.1 - 0.03 15.0 0.0 0.11 13.2 0.0 2.0 1 0 0 1 1 1 0 Protein kinase C terminal domain SET_assoc PF11767.8 CBZ38434.1 - 0.047 13.3 2.0 8.9 6.0 0.0 3.6 4 0 0 4 4 4 0 Histone lysine methyltransferase SET associated RRM_8 PF11835.8 CBZ38434.1 - 0.054 13.7 0.0 0.68 10.2 0.0 2.7 4 0 0 4 4 4 0 RRM-like domain XS PF03468.14 CBZ38434.1 - 0.26 11.6 2.9 10 6.4 0.2 3.2 2 1 1 3 3 3 0 XS domain bVLRF1 PF18826.1 CBZ38436.1 - 1.2e-38 132.3 0.0 2.5e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor FUSC PF04632.12 CBZ38436.1 - 0.94 7.9 3.5 0.38 9.2 0.6 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family EF-hand_6 PF13405.6 CBZ38437.1 - 0.069 13.1 1.0 0.11 12.5 0.1 1.8 2 0 0 2 2 2 0 EF-hand domain TF_Zn_Ribbon PF08271.12 CBZ38437.1 - 0.07 12.7 0.5 0.2 11.2 0.5 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding PK PF00224.21 CBZ38438.1 - 2.1e-155 516.9 2.0 2.7e-155 516.5 2.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CBZ38438.1 - 8.8e-26 90.4 0.4 8.8e-26 90.4 0.4 2.2 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CBZ38438.1 - 0.00033 19.8 0.7 0.0011 18.1 0.7 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 CBZ38438.1 - 0.4 9.6 4.9 0.36 9.8 0.1 2.5 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain CENP-T_C PF15511.6 CBZ38440.1 - 6.8e-07 29.4 0.1 1e-06 28.8 0.0 1.2 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBZ38440.1 - 3.6e-05 24.0 0.1 5.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CBZ38440.1 - 0.0002 21.4 0.1 0.0003 20.9 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CBZ38440.1 - 0.00065 19.7 0.0 0.00082 19.3 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ38440.1 - 0.0031 17.9 2.2 0.0063 16.9 2.2 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ38440.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_S17e PF00833.18 CBZ38440.1 - 0.045 13.7 0.6 0.054 13.4 0.6 1.1 1 0 0 1 1 1 0 Ribosomal S17 Ly-6_related PF06579.12 CBZ38440.1 - 0.071 13.4 0.6 0.088 13.1 0.6 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein DUF4400 PF14348.6 CBZ38440.1 - 0.09 12.3 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) PCP_red PF08369.10 CBZ38440.1 - 0.16 12.2 2.1 0.2 11.9 0.4 2.1 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit CENP-T_C PF15511.6 CBZ38441.1 - 6.8e-07 29.4 0.1 1e-06 28.8 0.0 1.2 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CBZ38441.1 - 3.6e-05 24.0 0.1 5.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CBZ38441.1 - 0.0002 21.4 0.1 0.0003 20.9 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CBZ38441.1 - 0.00065 19.7 0.0 0.00082 19.3 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CBZ38441.1 - 0.0031 17.9 2.2 0.0063 16.9 2.2 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CBZ38441.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_S17e PF00833.18 CBZ38441.1 - 0.045 13.7 0.6 0.054 13.4 0.6 1.1 1 0 0 1 1 1 0 Ribosomal S17 Ly-6_related PF06579.12 CBZ38441.1 - 0.071 13.4 0.6 0.088 13.1 0.6 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein DUF4400 PF14348.6 CBZ38441.1 - 0.09 12.3 0.2 0.14 11.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) PCP_red PF08369.10 CBZ38441.1 - 0.16 12.2 2.1 0.2 11.9 0.4 2.1 2 1 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Amidohydro_1 PF01979.20 CBZ38443.1 - 3.2e-09 36.6 2.5 7.2e-08 32.1 2.5 2.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CBZ38443.1 - 2.7e-08 33.7 0.1 0.024 14.1 0.0 3.1 3 0 0 3 3 3 3 Amidohydrolase family PUF PF00806.19 CBZ38444.1 - 6.7e-33 110.5 11.5 7.7e-06 25.3 0.1 7.4 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat CPL PF08144.11 CBZ38444.1 - 8.1e-06 26.2 1.5 4.5 7.6 0.0 4.1 2 1 3 5 5 5 3 CPL (NUC119) domain TFIIB_C_1 PF18542.1 CBZ38444.1 - 0.022 14.8 1.3 0.037 14.1 0.2 2.0 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 CYTH PF01928.21 CBZ38444.1 - 0.11 12.4 0.0 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 CYTH domain REV1_C PF16727.5 CBZ38444.1 - 0.16 12.4 0.0 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain FGGY_C PF02782.16 CBZ38445.1 - 1.4e-36 126.2 0.1 2.4e-36 125.3 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CBZ38445.1 - 1.4e-05 24.8 0.0 3.5e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain SAP PF02037.27 CBZ38446.1 - 2.2e-12 46.4 0.4 4.8e-12 45.3 0.4 1.5 1 0 0 1 1 1 1 SAP domain TPR_1 PF00515.28 CBZ38447.1 - 3.2e-41 137.5 14.2 7.5e-08 31.9 0.0 6.2 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ38447.1 - 1.8e-35 118.2 10.9 5.8e-09 35.4 0.0 6.3 6 1 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ38447.1 - 6e-25 85.3 7.6 4.7e-06 26.4 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38447.1 - 1.7e-23 82.0 9.2 0.00011 21.8 0.3 6.2 4 2 2 6 6 6 5 TPR repeat TPR_7 PF13176.6 CBZ38447.1 - 7.9e-18 63.1 1.5 0.00022 21.0 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38447.1 - 2.3e-16 59.8 7.3 0.00071 19.8 0.1 4.3 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ38447.1 - 3.6e-14 53.1 1.8 0.014 16.0 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38447.1 - 1.2e-12 47.5 1.7 0.00095 19.8 0.0 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ38447.1 - 3.4e-12 45.9 6.1 0.019 15.3 0.1 6.3 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ38447.1 - 7.5e-11 41.9 7.0 0.00022 21.7 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ38447.1 - 1.3e-10 41.6 5.7 0.0029 18.1 0.1 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ38447.1 - 8.8e-10 38.6 0.1 0.0012 19.0 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBZ38447.1 - 8.3e-09 34.8 4.2 0.0099 15.3 0.0 5.0 5 0 0 5 5 5 2 SHNi-TPR MIT PF04212.18 CBZ38447.1 - 4.3e-07 29.9 10.7 0.09 12.9 0.1 4.4 4 0 0 4 4 4 3 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CBZ38447.1 - 1.2e-06 28.2 8.3 0.39 10.7 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ38447.1 - 1.1e-05 25.6 2.6 0.3 11.3 0.1 3.6 2 1 1 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 CBZ38447.1 - 0.0002 21.3 5.5 0.16 12.0 0.1 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.7 CBZ38447.1 - 0.00023 21.3 2.9 0.17 11.9 0.1 3.4 2 2 0 2 2 2 2 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 CBZ38447.1 - 0.0003 20.8 0.8 0.095 12.8 0.0 4.4 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat SPO22 PF08631.10 CBZ38447.1 - 0.00033 20.2 3.7 0.022 14.3 0.3 3.2 3 1 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like DUF2225 PF09986.9 CBZ38447.1 - 0.013 15.2 4.0 0.36 10.5 0.1 2.9 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_15 PF13429.6 CBZ38447.1 - 0.021 14.0 1.1 2 7.6 0.1 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 CBZ38447.1 - 0.028 15.1 8.3 3.6 8.4 0.2 4.2 3 1 1 4 4 4 0 Sel1 repeat MAS20 PF02064.15 CBZ38447.1 - 0.039 14.0 1.8 5.7 7.1 0.4 3.0 2 1 1 3 3 3 0 MAS20 protein import receptor Rota_NSP3 PF01665.16 CBZ38447.1 - 0.05 12.7 0.2 0.8 8.8 0.0 2.3 1 1 1 2 2 2 0 Rotavirus non-structural protein NSP3 TPR_MalT PF17874.1 CBZ38447.1 - 0.085 12.2 0.1 4 6.7 0.1 2.4 1 1 1 2 2 2 0 MalT-like TPR region Egg_lysin PF01303.17 CBZ38447.1 - 0.12 12.6 1.0 0.37 11.0 0.1 2.0 2 1 0 2 2 2 0 Egg lysin (Sperm-lysin) BTAD PF03704.17 CBZ38447.1 - 0.13 12.7 0.9 3 8.3 0.0 3.0 2 2 1 3 3 3 0 Bacterial transcriptional activator domain LCM PF04072.14 CBZ38448.1 - 9.7e-24 84.3 0.0 3.7e-23 82.4 0.0 1.8 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase IMS PF00817.20 CBZ38450.1 - 1.1e-34 119.6 0.1 2.9e-34 118.2 0.1 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 CBZ38450.1 - 0.0028 18.3 0.0 0.0071 17.0 0.0 1.7 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain Pox_MCEL PF03291.16 CBZ38452.1 - 1.5e-31 109.8 0.0 9.3e-31 107.1 0.0 1.8 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CBZ38452.1 - 0.015 16.0 0.1 0.08 13.6 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CBZ38452.1 - 0.016 14.4 0.0 0.43 9.7 0.1 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 CBZ38452.1 - 0.061 13.2 0.0 0.21 11.4 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ38452.1 - 0.066 14.0 0.0 0.3 11.9 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain PUB PF09409.10 CBZ38453.1 - 1.4e-16 60.1 0.0 3.2e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 PUB domain LIAS_N PF16881.5 CBZ38453.1 - 0.079 13.4 1.1 0.17 12.3 1.1 1.6 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family DUF572 PF04502.13 CBZ38453.1 - 4.2 6.9 14.2 6.4 6.3 14.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) His_Phos_1 PF00300.22 CBZ38455.1 - 3.5e-28 98.6 0.0 1.5e-27 96.6 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CBZ38455.1 - 0.081 12.3 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) EFG_C PF00679.24 CBZ38458.1 - 3.5e-20 71.8 0.0 4.2e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU PF00009.27 CBZ38459.1 - 5.7e-65 218.5 0.5 9.5e-65 217.8 0.5 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CBZ38459.1 - 2.6e-29 101.5 0.0 7.2e-29 100.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CBZ38459.1 - 6.4e-20 71.0 0.0 2.9e-19 68.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 CBZ38459.1 - 5.7e-14 52.0 0.0 3.1e-13 49.6 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CBZ38459.1 - 6e-14 52.2 0.1 1.6e-13 50.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CBZ38459.1 - 0.0019 18.2 0.1 0.0051 16.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_S24 PF00717.23 CBZ38460.1 - 1.4e-06 28.1 0.0 2.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CBZ38460.1 - 0.0084 15.9 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 SET PF00856.28 CBZ38461.1 - 2.3e-11 44.4 0.1 1.9e-09 38.1 0.1 2.3 1 1 0 1 1 1 1 SET domain RimK PF08443.11 CBZ38461.1 - 0.0018 17.9 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Glycos_transf_2 PF00535.26 CBZ38462.1 - 5.8e-35 120.6 0.0 7.3e-35 120.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CBZ38462.1 - 6e-06 26.3 0.0 8.2e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CBZ38462.1 - 0.011 16.3 0.0 0.019 15.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 FKBP_C PF00254.28 CBZ38463.1 - 5.3e-27 94.0 0.0 6.7e-27 93.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ADIP PF11559.8 CBZ38464.1 - 5.5e-06 26.5 16.0 5.5e-06 26.5 16.0 1.9 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF4164 PF13747.6 CBZ38464.1 - 4.1e-05 23.8 6.4 4.1e-05 23.8 6.4 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4164) KASH_CCD PF14662.6 CBZ38464.1 - 0.00036 20.4 21.0 0.00036 20.4 21.0 1.6 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH V_ATPase_I PF01496.19 CBZ38464.1 - 0.033 12.1 3.8 0.041 11.8 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.21 CBZ38464.1 - 0.038 14.1 1.3 0.038 14.1 1.3 2.9 3 0 0 3 3 3 0 bZIP transcription factor FapA PF03961.13 CBZ38464.1 - 0.12 10.9 7.2 0.45 9.1 7.2 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A YabA PF06156.13 CBZ38464.1 - 0.16 12.6 13.4 3.9 8.2 5.3 2.9 2 1 1 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 CBZ38464.1 - 0.16 12.0 23.1 0.19 11.7 20.0 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Golgin_A5 PF09787.9 CBZ38464.1 - 0.36 10.3 16.8 0.073 12.5 13.0 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 CENP-H PF05837.12 CBZ38464.1 - 0.4 11.1 17.1 2.6 8.5 13.3 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) GAS PF13851.6 CBZ38464.1 - 0.44 9.9 19.2 1.9 7.8 17.3 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 CBZ38464.1 - 0.52 10.3 5.2 0.98 9.5 4.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DivIC PF04977.15 CBZ38464.1 - 0.69 9.7 22.0 2 8.2 7.8 3.4 2 1 1 3 3 3 0 Septum formation initiator Sec34 PF04136.15 CBZ38464.1 - 0.69 9.8 8.4 0.96 9.3 4.7 2.5 2 1 1 3 3 3 0 Sec34-like family FlaC_arch PF05377.11 CBZ38464.1 - 0.71 10.3 7.6 0.23 11.9 2.1 2.6 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 CBZ38464.1 - 0.73 10.1 16.7 0.093 13.0 10.7 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 CBZ38464.1 - 1.1 9.1 8.4 5 6.9 7.9 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 RskA PF10099.9 CBZ38464.1 - 1.1 9.5 5.9 1.6 9.0 5.9 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF2959 PF11172.8 CBZ38464.1 - 1.2 9.2 11.1 7.4 6.7 7.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) Enkurin PF13864.6 CBZ38464.1 - 1.2 9.6 15.9 1 9.8 13.2 2.1 2 0 0 2 2 2 0 Calmodulin-binding Atg14 PF10186.9 CBZ38464.1 - 1.9 7.5 22.3 0.38 9.8 14.2 2.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 CBZ38464.1 - 2 8.5 26.2 0.5 10.4 2.1 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein HIP1_clath_bdg PF16515.5 CBZ38464.1 - 2 9.1 20.8 11 6.7 0.1 2.8 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PRKG1_interact PF15898.5 CBZ38464.1 - 3.8 8.5 21.5 5.2 8.0 17.0 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 CBZ38464.1 - 6.1 5.6 20.5 1.2 7.9 16.8 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 CBZ38464.1 - 7.2 6.4 15.2 11 5.7 10.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4446 PF14584.6 CBZ38464.1 - 10 6.1 10.6 0.23 11.5 1.9 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Paf67 PF10255.9 CBZ38465.1 - 1.3e-49 169.3 0.0 3e-49 168.1 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 FGGY_N PF00370.21 CBZ38466.1 - 2.8e-07 30.4 0.0 2.9e-07 30.3 0.0 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain ROK PF00480.20 CBZ38466.1 - 0.19 11.2 0.0 0.19 11.2 0.0 1.0 1 0 0 1 1 1 0 ROK family CH PF00307.31 CBZ38467.1 - 0.022 14.9 0.0 7.6 6.8 0.0 2.9 3 0 0 3 3 3 0 Calponin homology (CH) domain TFIIS_M PF07500.14 CBZ38468.1 - 5.3e-05 23.7 1.8 0.00013 22.4 1.8 1.7 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Cys_rich_KTR PF14205.6 CBZ38468.1 - 0.15 11.9 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 Cysteine-rich KTR NUDIX PF00293.28 CBZ38470.1 - 1.7e-13 50.7 0.0 2.9e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain ESCRT-II PF05871.12 CBZ38471.1 - 8.9e-13 48.7 0.0 6.4e-12 45.9 0.0 2.0 1 1 0 1 1 1 1 ESCRT-II complex subunit MiaE_2 PF13794.6 CBZ38471.1 - 0.1 12.3 0.1 15 5.2 0.0 2.2 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like DUF3223 PF11523.8 CBZ38471.1 - 0.12 13.2 0.1 1.2 10.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3223) Proteasome PF00227.26 CBZ38472.1 - 1.6e-26 93.0 0.0 1.9e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RNase_HII PF01351.18 CBZ38474.1 - 2.3e-19 70.0 0.0 8.1e-11 42.1 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease HII Nop10p PF04135.12 CBZ38475.1 - 2.1e-22 78.9 0.4 2.6e-22 78.6 0.4 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family EMC3_TMCO1 PF01956.16 CBZ38477.1 - 3.7e-47 160.2 3.7 3.7e-47 160.2 3.7 1.5 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like DUF5326 PF17260.2 CBZ38477.1 - 0.063 13.4 0.9 0.16 12.1 0.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5326) PIP5K PF01504.18 CBZ38478.1 - 3.3e-55 187.2 0.0 5.2e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase TFIIA PF03153.13 CBZ38479.1 - 1.6 8.6 10.9 1.7 8.6 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 CBZ38479.1 - 8.6 4.9 6.9 9.8 4.7 6.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DB_JBP1 PF18526.1 CBZ38480.1 - 0.002 18.1 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Thymine dioxygenase JBP1 DNA-binding domain Med3 PF11593.8 CBZ38480.1 - 0.0046 16.2 2.9 0.0046 16.2 2.9 1.8 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal Pex14_N PF04695.13 CBZ38480.1 - 0.2 12.3 6.4 0.72 10.5 6.4 2.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.9 CBZ38480.1 - 1.8 7.0 5.4 2.2 6.7 5.4 1.1 1 0 0 1 1 1 0 Macoilin family NUDE_C PF04880.13 CBZ38480.1 - 2.1 8.8 14.5 6.4 7.2 14.5 1.8 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DUF4614 PF15391.6 CBZ38480.1 - 2.7 8.0 13.1 5.2 7.0 13.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 CBZ38480.1 - 5 5.9 10.3 7.3 5.3 10.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FAM199X PF15814.5 CBZ38480.1 - 6.8 5.7 17.4 11 5.0 17.4 1.3 1 0 0 1 1 1 0 Protein family FAM199X MRI PF15325.6 CBZ38480.1 - 9 7.4 11.9 20 6.3 11.9 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection PDZ_2 PF13180.6 CBZ38481.1 - 3.9e-05 23.9 0.1 9.9e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CBZ38481.1 - 0.0028 18.0 0.0 0.0061 16.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain HTH_50 PF18024.1 CBZ38481.1 - 0.048 13.3 0.1 0.45 10.2 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain PI3K_P85_iSH2 PF16454.5 CBZ38481.1 - 0.26 10.9 3.7 0.18 11.4 1.6 1.8 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain THOC7 PF05615.13 CBZ38481.1 - 0.64 10.3 8.1 4.7 7.5 3.8 2.3 2 0 0 2 2 2 0 Tho complex subunit 7 Baculo_PEP_C PF04513.12 CBZ38481.1 - 1.5 8.8 4.4 10 6.2 3.8 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BMFP PF04380.13 CBZ38481.1 - 2.4 8.7 11.7 3 8.4 0.3 3.0 3 0 0 3 3 3 0 Membrane fusogenic activity ArnB_C PF18677.1 CBZ38482.1 - 0.019 15.1 3.8 0.038 14.1 3.8 1.5 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Histone_HNS PF00816.21 CBZ38482.1 - 0.14 13.0 0.7 0.2 12.5 0.2 1.5 2 0 0 2 2 2 0 H-NS histone family Aa_trans PF01490.18 CBZ38483.1 - 9.9e-64 215.5 16.4 1.1e-63 215.3 16.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CBZ38483.1 - 2e-07 30.4 16.3 2e-07 30.4 16.3 2.0 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family TMEM70 PF06979.12 CBZ38483.1 - 0.45 10.9 8.4 0.93 9.9 0.1 3.5 2 1 1 3 3 3 0 Assembly, mitochondrial proton-transport ATP synth complex Stevor PF17410.2 CBZ38483.1 - 3.1 7.3 3.7 11 5.5 0.0 2.1 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame TFIIA_gamma_C PF02751.14 CBZ38484.1 - 0.001 19.2 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 CBZ38484.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain DUF1634 PF07843.11 CBZ38485.1 - 0.097 12.8 0.4 0.3 11.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) YPEB PF14620.6 CBZ38486.1 - 0.054 12.8 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 YpeB sporulation Sec1 PF00995.23 CBZ38487.1 - 5.3e-105 352.8 0.1 7.1e-105 352.4 0.1 1.2 1 0 0 1 1 1 1 Sec1 family Dus PF01207.17 CBZ38488.1 - 1.5e-35 122.8 0.3 3.7e-31 108.4 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-ANAPC11 PF12861.7 CBZ38489.1 - 0.022 14.8 0.8 0.039 14.0 0.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C2HC_2 PF13913.6 CBZ38490.1 - 1.2e-15 57.0 6.1 2.5e-10 40.0 1.3 2.3 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 CBZ38490.1 - 0.013 15.9 0.4 7.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 CBZ38490.1 - 0.031 14.3 2.2 3.1 7.9 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CBZ38490.1 - 0.049 14.5 1.3 10 7.3 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CBZ38490.1 - 0.26 11.8 3.3 20 5.9 1.6 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DnaJ PF00226.31 CBZ38491.1 - 2.3e-21 75.7 2.0 7e-21 74.1 0.6 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 CBZ38491.1 - 2.1e-18 64.8 23.8 0.00028 20.8 0.1 8.1 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ38491.1 - 5e-12 46.2 18.6 0.0021 18.5 0.7 6.6 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ38491.1 - 3.7e-11 42.4 22.5 0.0023 17.7 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38491.1 - 8.6e-10 38.6 18.4 0.014 16.2 0.1 7.2 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ38491.1 - 6.9e-09 35.7 15.2 0.013 15.6 0.3 5.9 3 2 2 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ38491.1 - 1.2e-08 35.4 18.6 0.00014 22.5 1.9 5.7 3 2 3 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ38491.1 - 1.3e-07 31.5 10.7 0.0011 19.2 0.1 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38491.1 - 2.3e-07 30.4 20.6 2.3e-05 23.9 0.4 5.5 6 2 1 7 7 6 3 TPR repeat TPR_8 PF13181.6 CBZ38491.1 - 3.2e-07 30.1 12.1 0.055 13.7 0.1 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38491.1 - 2.6e-05 24.4 17.6 0.0032 17.7 1.6 5.8 4 2 2 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ38491.1 - 0.0002 21.5 10.9 0.0044 17.2 0.1 4.2 2 2 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CBZ38491.1 - 0.0038 17.0 0.2 0.0038 17.0 0.2 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat 3HCDH_RFF PF18321.1 CBZ38491.1 - 0.0074 16.7 0.3 0.065 13.7 0.0 2.6 1 1 1 2 2 2 1 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain TPR_7 PF13176.6 CBZ38491.1 - 0.0094 15.9 10.1 11 6.3 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat LPD7 PF18821.1 CBZ38491.1 - 0.095 12.8 3.8 1 9.5 0.1 3.1 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 7 Fis1_TPR_C PF14853.6 CBZ38491.1 - 0.21 11.7 4.2 1.1 9.4 0.3 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.9 CBZ38491.1 - 3.5 7.2 6.8 18 4.9 0.0 3.4 4 0 0 4 4 4 0 SHNi-TPR DUF3856 PF12968.7 CBZ38491.1 - 4.7 7.3 8.5 5.4 7.1 0.9 4.0 2 2 1 3 3 3 0 Domain of Unknown Function (DUF3856) DUF4407 PF14362.6 CBZ38491.1 - 5.2 6.3 10.4 11 5.3 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mito_carr PF00153.27 CBZ38492.1 - 2.8e-88 290.0 21.0 3.3e-21 75.0 0.0 6.2 5 1 1 6 6 6 6 Mitochondrial carrier protein Serine_protease PF18405.1 CBZ38492.1 - 0.00078 18.7 5.2 0.84 8.7 0.0 4.3 5 0 0 5 5 5 3 Gammaproteobacterial serine protease ThrE PF06738.12 CBZ38492.1 - 0.37 10.1 3.1 0.39 10.1 0.7 2.3 2 1 0 2 2 2 0 Putative threonine/serine exporter PP2C PF00481.21 CBZ38494.1 - 2.6e-70 237.0 0.6 3.3e-70 236.7 0.6 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CBZ38494.1 - 0.012 15.6 0.0 0.47 10.4 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CBZ38494.1 - 0.03 14.0 0.1 0.053 13.1 0.1 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C LSM PF01423.22 CBZ38495.1 - 1.3e-07 31.2 0.0 1.8e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CBZ38495.1 - 0.036 14.2 0.2 0.1 12.7 0.0 1.8 3 0 0 3 3 3 0 Ataxin 2 SM domain LSM14 PF12701.7 CBZ38495.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Scd6-like Sm domain EFG_IV PF03764.18 CBZ38495.1 - 0.053 13.3 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Elongation factor G, domain IV DUF5623 PF18536.1 CBZ38496.1 - 0.0043 17.3 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5623) ubiquitin PF00240.23 CBZ38497.1 - 2.9e-16 59.0 0.1 5.2e-16 58.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CBZ38497.1 - 4.3e-06 26.5 0.8 1.2e-05 25.1 0.8 1.9 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 CBZ38497.1 - 1.2e-05 25.0 0.1 2.1e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ComX PF05952.12 CBZ38497.1 - 0.0047 16.8 2.5 0.013 15.4 2.5 1.8 1 0 0 1 1 1 1 Bacillus competence pheromone ComX Ubiquitin_2 PF14560.6 CBZ38497.1 - 0.0056 17.1 0.0 0.017 15.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain RNA_pol_Rpb5_C PF01191.19 CBZ38497.1 - 0.0065 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain DUF2407 PF10302.9 CBZ38497.1 - 0.01 16.4 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 CBZ38497.1 - 0.015 15.7 0.1 0.027 14.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain YukD PF08817.10 CBZ38497.1 - 0.02 15.6 0.1 0.087 13.5 0.0 2.1 3 0 0 3 3 2 0 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD_2 PF13881.6 CBZ38497.1 - 0.046 13.8 0.1 0.12 12.5 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.11 CBZ38497.1 - 0.094 12.5 18.9 0.33 10.7 18.9 2.0 1 0 0 1 1 1 0 XPC-binding domain Ubiquitin_4 PF18036.1 CBZ38497.1 - 0.12 12.5 0.1 18 5.4 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain HOIP-UBA PF16678.5 CBZ38497.1 - 0.18 11.8 0.8 0.34 10.9 0.1 1.8 2 0 0 2 2 2 0 HOIP UBA domain pair GerD PF17898.1 CBZ38497.1 - 0.27 11.2 14.9 0.4 10.6 13.0 2.1 2 0 0 2 2 2 0 Spore germination GerD central core domain TFIIA PF03153.13 CBZ38497.1 - 1.5 8.7 12.9 1.8 8.5 12.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit STI1 PF17830.1 CBZ38497.1 - 2.6 8.0 25.2 0.79 9.7 12.0 2.9 1 1 1 2 2 2 0 STI1 domain Pkinase PF00069.25 CBZ38498.1 - 1.9e-79 266.7 0.0 2.2e-79 266.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38498.1 - 2.1e-35 122.3 0.0 4.3e-35 121.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CBZ38498.1 - 0.0009 19.2 0.3 0.02 14.8 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ38498.1 - 0.014 14.4 0.0 0.074 12.0 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 CBZ38498.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Syntaxin_2 PF14523.6 CBZ38499.1 - 0.68 10.3 10.4 0.65 10.4 6.2 2.8 1 1 1 2 2 2 0 Syntaxin-like protein DUF3450 PF11932.8 CBZ38499.1 - 2.6 7.3 28.8 0.64 9.3 3.1 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) FlxA PF14282.6 CBZ38499.1 - 3.9 7.5 18.4 3.7 7.6 0.2 3.7 1 1 1 3 3 3 0 FlxA-like protein YabA PF06156.13 CBZ38499.1 - 7.6 7.2 20.1 1.7 9.3 3.2 3.8 2 1 2 4 4 4 0 Initiation control protein YabA GTP_EFTU PF00009.27 CBZ38500.1 - 2.3e-62 210.0 0.0 3.8e-62 209.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CBZ38500.1 - 3.7e-24 84.6 0.0 8.4e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CBZ38500.1 - 5.9e-21 74.3 0.1 2e-20 72.6 0.1 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.18 CBZ38500.1 - 4.2e-18 65.3 0.0 1e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 CBZ38500.1 - 2.3e-07 31.1 0.0 8.7e-07 29.2 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CBZ38500.1 - 4.1e-05 23.4 0.1 0.00018 21.3 0.0 2.1 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CBZ38500.1 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CBZ38500.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 AIG1 family DUF4132 PF13569.6 CBZ38500.1 - 0.023 14.5 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) DUF442 PF04273.13 CBZ38500.1 - 0.11 12.6 0.1 3.5 7.8 0.0 2.9 2 1 1 3 3 3 0 Putative phosphatase (DUF442) FeoB_N PF02421.18 CBZ38500.1 - 0.11 12.1 0.1 0.77 9.3 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B WD40 PF00400.32 CBZ38501.1 - 6.4e-09 36.3 11.1 0.00096 19.9 0.1 6.1 7 0 0 7 7 7 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CBZ38501.1 - 0.00014 21.0 1.4 0.056 12.4 0.0 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CRAL_TRIO PF00650.20 CBZ38502.1 - 4e-23 81.9 0.0 6.3e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CAP_GLY PF01302.25 CBZ38502.1 - 6.8e-11 42.0 0.8 1.2e-10 41.3 0.8 1.4 1 0 0 1 1 1 1 CAP-Gly domain CRAL_TRIO_N PF03765.15 CBZ38502.1 - 0.0059 16.8 0.2 0.012 15.8 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain IF4E PF01652.18 CBZ38503.1 - 3.8e-09 36.5 0.0 4.5e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Ribosomal_S27 PF01599.19 CBZ38504.1 - 5e-23 81.0 4.0 9.4e-23 80.1 4.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 CBZ38504.1 - 3e-10 39.7 0.1 1.7e-09 37.3 0.0 2.2 2 1 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CBZ38504.1 - 2.2e-06 27.4 0.2 2.5e-05 24.0 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.21 CBZ38504.1 - 0.0044 17.2 0.7 0.0078 16.4 0.7 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain DnaJ PF00226.31 CBZ38505.1 - 1.5e-22 79.5 0.5 1.5e-22 79.5 0.5 1.9 3 0 0 3 3 3 1 DnaJ domain ATP-synt_Eps PF04627.13 CBZ38506.1 - 1e-05 25.4 0.2 2.5e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DUF3592 PF12158.8 CBZ38507.1 - 1.3e-19 70.8 0.5 1.4e-19 70.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3592) RNase_HII PF01351.18 CBZ38508.1 - 5.6e-31 107.9 0.0 7.8e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Alg14 PF08660.11 CBZ38508.1 - 0.0031 17.5 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like PIG-U PF06728.13 CBZ38509.1 - 7.2e-07 28.6 22.1 9.6e-06 24.9 22.1 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U EamA PF00892.20 CBZ38511.1 - 4.8e-07 30.0 31.3 4.2e-06 27.0 1.9 4.5 5 0 0 5 5 5 3 EamA-like transporter family UAA PF08449.11 CBZ38511.1 - 2.6e-06 26.9 1.0 2.6e-06 26.9 1.0 2.5 2 1 0 3 3 3 2 UAA transporter family CRT-like PF08627.10 CBZ38511.1 - 4.3e-05 22.6 13.7 8e-05 21.7 13.7 1.4 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SSB PF00436.25 CBZ38514.1 - 1.1e-05 25.4 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 CBZ38514.1 - 0.05 13.6 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain LRR_9 PF14580.6 CBZ38515.1 - 3.4e-12 46.2 0.8 1.1e-11 44.5 0.1 2.1 2 1 1 3 3 3 1 Leucine-rich repeat LRR_4 PF12799.7 CBZ38515.1 - 6e-07 29.7 0.3 0.06 13.8 0.0 3.1 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ38515.1 - 9.2e-07 28.5 0.5 5.9e-05 22.7 0.1 2.7 1 1 1 2 2 2 2 Leucine rich repeat MSA-2c PF12238.8 CBZ38515.1 - 0.99 9.4 3.8 1.9 8.4 2.0 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c Ribosomal_60s PF00428.19 CBZ38515.1 - 1.4 9.5 5.2 0.42 11.2 2.0 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Pkinase PF00069.25 CBZ38516.1 - 2.8e-69 233.4 0.0 3.6e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38516.1 - 6.5e-35 120.7 0.0 8.9e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ38516.1 - 0.00013 21.3 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBZ38516.1 - 0.0014 18.0 1.7 0.0027 17.1 1.7 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CBZ38516.1 - 0.015 14.3 2.1 0.042 12.8 2.1 1.7 1 1 0 1 1 1 0 Haspin like kinase domain FeoB_N PF02421.18 CBZ38516.1 - 0.12 11.9 0.2 0.23 11.0 0.2 1.4 1 1 0 1 1 1 0 Ferrous iron transport protein B APH PF01636.23 CBZ38516.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CBZ38516.1 - 0.21 10.4 1.5 0.45 9.2 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase Torus PF16131.5 CBZ38517.1 - 5.6e-07 30.2 5.5 0.00044 20.9 0.1 3.2 3 0 0 3 3 3 2 Torus domain zf-CCCH PF00642.24 CBZ38517.1 - 0.00063 19.6 17.0 0.061 13.3 0.4 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CBZ38517.1 - 0.004 16.9 2.8 0.004 16.9 2.8 3.4 3 0 0 3 3 3 2 CCCH-type zinc finger DUF459 PF04311.13 CBZ38517.1 - 0.072 12.1 3.4 0.12 11.4 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Torus PF16131.5 CBZ38518.1 - 1.6e-05 25.6 8.6 0.0002 22.0 0.1 3.8 2 1 1 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 CBZ38518.1 - 0.0027 17.5 1.8 0.0027 17.5 1.8 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CBZ38518.1 - 0.0077 16.3 1.2 0.0077 16.3 1.2 2.7 3 0 0 3 3 3 1 Zinc finger domain XPC-binding PF09280.11 CBZ38519.1 - 0.00045 19.9 0.0 0.00096 18.8 0.0 1.6 1 0 0 1 1 1 1 XPC-binding domain Plasmid_RAQPRD PF09686.10 CBZ38519.1 - 0.039 14.1 0.3 0.14 12.3 0.3 2.0 1 0 0 1 1 1 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TPR_1 PF00515.28 CBZ38520.1 - 1.6e-12 46.7 11.2 0.00016 21.3 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ38520.1 - 1.9e-11 43.2 28.7 0.014 15.5 0.2 8.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38520.1 - 4.7e-11 42.2 2.1 0.00073 19.2 0.0 4.7 4 0 0 4 4 4 2 TPR repeat DnaJ PF00226.31 CBZ38520.1 - 3.3e-09 36.7 0.3 1.1e-08 35.1 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain TPR_9 PF13371.6 CBZ38520.1 - 0.00025 21.1 25.5 1.5 9.1 0.4 6.0 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ38520.1 - 0.00038 20.4 6.6 0.68 10.3 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ38520.1 - 0.00086 19.2 8.5 0.83 9.8 0.2 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38520.1 - 0.004 17.4 3.8 0.004 17.4 3.8 5.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38520.1 - 0.0078 17.0 41.4 0.18 12.7 0.7 8.0 5 3 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ38520.1 - 0.0081 16.5 2.2 8.8 7.0 0.2 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ38520.1 - 0.034 14.8 43.6 0.31 11.7 1.9 6.4 6 0 0 6 6 4 0 Tetratricopeptide repeat Peptidase_C2 PF00648.21 CBZ38522.1 - 4.1e-25 88.4 0.0 6.4e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Tfb2 PF03849.14 CBZ38524.1 - 9.7e-24 84.0 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.6 CBZ38524.1 - 1.1e-05 25.6 0.1 6.3e-05 23.1 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Tfb2_C PF18307.1 CBZ38524.1 - 0.19 12.2 0.3 0.36 11.3 0.3 1.5 1 0 0 1 1 1 0 Transcription factor Tfb2 (p52) C-terminal domain Arf PF00025.21 CBZ38526.1 - 6.2e-30 103.9 0.0 8.9e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CBZ38526.1 - 8.3e-09 35.1 0.0 4e-08 32.8 0.0 2.0 2 1 1 3 3 3 1 G-protein alpha subunit Ras PF00071.22 CBZ38526.1 - 2.9e-08 33.5 0.0 4.4e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CBZ38526.1 - 5.3e-08 33.1 0.0 9.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CBZ38526.1 - 1.3e-05 24.8 0.0 2.7e-05 23.7 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit DUF5586 PF17824.1 CBZ38526.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) DUF5582 PF17819.1 CBZ38526.1 - 0.21 12.1 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5582) cNMP_binding PF00027.29 CBZ38527.1 - 2.2e-17 62.9 0.0 2.5e-10 40.3 0.1 4.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain C2 PF00168.30 CBZ38527.1 - 8.1e-09 35.7 0.0 0.012 15.9 0.0 4.5 4 0 0 4 4 4 2 C2 domain cNMP_binding PF00027.29 CBZ38528.1 - 2.2e-17 62.9 0.0 2.5e-10 40.3 0.1 4.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain C2 PF00168.30 CBZ38528.1 - 8.1e-09 35.7 0.0 0.012 15.9 0.0 4.5 4 0 0 4 4 4 2 C2 domain Torus PF16131.5 CBZ38529.1 - 1.7e-07 31.9 1.3 0.00035 21.2 0.0 2.7 2 0 0 2 2 2 2 Torus domain zf-CCCH PF00642.24 CBZ38529.1 - 0.023 14.6 11.5 0.039 13.9 0.4 2.9 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HALZ PF02183.18 CBZ38529.1 - 0.054 13.7 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Macoilin PF09726.9 CBZ38530.1 - 0.0072 15.0 5.8 0.0098 14.5 5.8 1.1 1 0 0 1 1 1 1 Macoilin family LRRFIP PF09738.9 CBZ38530.1 - 0.0085 15.6 10.7 0.014 14.9 10.7 1.2 1 0 0 1 1 1 1 LRRFIP family WDCP PF15390.6 CBZ38530.1 - 0.021 13.3 10.3 0.035 12.5 10.3 1.3 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family ABC_tran_CTD PF16326.5 CBZ38530.1 - 0.025 14.8 0.8 0.025 14.8 0.8 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain Exonuc_VII_L PF02601.15 CBZ38530.1 - 0.12 11.9 10.0 0.23 11.0 10.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_DNA_bd PF12329.8 CBZ38530.1 - 0.17 11.9 9.5 2.7 8.0 2.5 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.15 CBZ38530.1 - 0.28 11.0 12.0 0.056 13.2 1.1 2.7 2 1 0 2 2 2 0 Septum formation initiator TMCO5 PF14992.6 CBZ38530.1 - 0.44 10.1 5.2 0.69 9.4 5.2 1.2 1 0 0 1 1 1 0 TMCO5 family Cep57_MT_bd PF06657.13 CBZ38530.1 - 0.69 10.4 12.6 1.3 9.6 1.0 2.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 LCIB_C_CA PF18599.1 CBZ38530.1 - 0.77 9.0 3.8 1.5 8.1 3.8 1.4 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases SlyX PF04102.12 CBZ38530.1 - 1.3 9.7 19.4 3.3 8.4 2.3 3.2 2 1 1 3 3 3 0 SlyX Fib_alpha PF08702.10 CBZ38530.1 - 1.6 8.9 6.3 4.7 7.4 0.3 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 CBZ38530.1 - 3 5.6 4.4 5.5 4.8 4.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 CBZ38530.1 - 4.2 6.6 14.4 6.6 6.0 14.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 CBZ38530.1 - 4.4 7.5 27.9 0.17 12.1 9.0 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Ribosomal_60s PF00428.19 CBZ38530.1 - 6.4 7.4 6.3 4.3 8.0 0.4 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein Spc24 PF08286.11 CBZ38530.1 - 7.4 6.9 7.0 1.1 9.5 0.3 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Pkinase PF00069.25 CBZ38531.1 - 1.1e-58 198.7 0.0 1.5e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38531.1 - 1.5e-32 112.9 0.0 2.1e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ38531.1 - 0.00026 19.9 0.0 0.00037 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CBZ38531.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CBZ38531.1 - 0.11 12.5 2.3 0.76 9.7 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CBZ38531.1 - 0.24 10.9 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase HA2 PF04408.23 CBZ38532.1 - 2.4e-17 63.2 0.0 7.5e-17 61.6 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CBZ38532.1 - 3.1e-15 56.5 0.0 1e-14 54.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ38532.1 - 2.4e-09 37.2 0.0 9.1e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 CBZ38532.1 - 1.2e-05 25.6 0.0 3.1e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 CBZ38532.1 - 0.0021 18.4 0.3 0.016 15.5 0.3 2.4 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 CBZ38532.1 - 0.0021 17.2 0.0 0.0061 15.7 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CBZ38532.1 - 0.0033 17.8 0.0 0.018 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 CBZ38532.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 CBZ38532.1 - 0.026 14.0 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 CBZ38532.1 - 0.048 13.4 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_23 PF13476.6 CBZ38532.1 - 0.055 14.0 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CBZ38532.1 - 0.068 12.7 0.2 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 CBZ38532.1 - 0.072 13.0 0.1 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 CBZ38532.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase ResIII PF04851.15 CBZ38532.1 - 0.11 12.5 0.0 2.2 8.3 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 CBZ38532.1 - 0.13 12.7 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CBZ38532.1 - 0.14 11.7 0.0 0.37 10.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region NifU PF01106.17 CBZ38533.1 - 1.7e-24 85.7 0.1 3.3e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CBZ38533.1 - 5.4e-12 45.6 0.0 1.7e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal eIF-6 PF01912.18 CBZ38534.1 - 4.7e-79 264.4 0.6 7.2e-79 263.8 0.4 1.3 2 0 0 2 2 2 1 eIF-6 family Pkinase PF00069.25 CBZ38535.1 - 1.1e-71 241.3 0.0 1.8e-71 240.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38535.1 - 1.7e-37 129.1 0.0 2.8e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ38535.1 - 7e-06 25.6 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBZ38535.1 - 0.0071 15.7 0.1 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CBZ38535.1 - 0.016 14.8 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 CBZ38535.1 - 0.043 13.7 0.1 1.6 8.6 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ38535.1 - 0.046 13.3 1.1 0.061 12.9 0.1 1.7 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 CBZ38536.1 - 9e-50 169.5 0.0 1.4e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38536.1 - 2.4e-30 105.7 0.0 3.8e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CBZ38536.1 - 0.00086 19.3 0.3 0.0049 16.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribonuclease_3 PF00636.26 CBZ38537.1 - 0.00018 22.1 0.0 0.034 14.8 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribosomal_S13 PF00416.22 CBZ38538.1 - 1.5e-44 151.4 0.3 1.8e-44 151.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Ribosomal_S13 PF00416.22 CBZ38539.1 - 1.5e-44 151.4 0.3 1.8e-44 151.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 AAA_6 PF12774.7 CBZ38540.1 - 9.4e-152 504.6 0.0 7.2e-151 501.7 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CBZ38540.1 - 4.9e-114 381.5 15.2 4.9e-114 381.5 15.2 3.9 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 CBZ38540.1 - 2.7e-102 342.1 0.0 2.7e-102 342.1 0.0 4.5 5 0 0 5 5 4 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 CBZ38540.1 - 3.7e-99 331.3 0.2 6.4e-98 327.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 CBZ38540.1 - 9.2e-77 257.1 0.0 9.2e-77 257.1 0.0 3.7 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 CBZ38540.1 - 2.7e-66 222.5 1.5 4.8e-64 215.2 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 CBZ38540.1 - 4e-52 176.3 0.0 1.9e-51 174.1 0.0 2.2 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CBZ38540.1 - 2.8e-47 159.7 0.1 3.8e-45 152.8 0.0 3.9 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 CBZ38540.1 - 3.3e-44 151.3 8.4 3.3e-44 151.3 8.4 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 CBZ38540.1 - 1.9e-24 86.2 0.3 1.3e-23 83.5 0.0 2.7 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 CBZ38540.1 - 2.2e-15 56.7 0.0 1.6e-14 53.9 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CBZ38540.1 - 2.9e-15 56.5 0.0 0.00026 21.0 0.0 7.3 6 2 0 6 6 6 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ38540.1 - 7.5e-09 36.0 2.9 7.9e-05 22.9 0.0 4.8 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 CBZ38540.1 - 1.5e-05 25.3 0.0 0.084 13.3 0.0 3.8 3 0 0 3 3 3 1 RNA helicase AAA PF00004.29 CBZ38540.1 - 3.1e-05 24.4 0.0 0.43 11.0 0.0 3.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CBZ38540.1 - 0.00011 22.1 0.1 0.029 14.3 0.0 3.8 2 0 0 2 2 2 1 NACHT domain ATG16 PF08614.11 CBZ38540.1 - 0.00027 21.2 9.8 0.00027 21.2 9.8 4.0 4 0 0 4 4 3 1 Autophagy protein 16 (ATG16) AAA_30 PF13604.6 CBZ38540.1 - 0.00058 19.6 0.0 0.95 9.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CBZ38540.1 - 0.0019 18.6 9.6 0.8 10.1 0.0 5.2 5 0 0 5 5 4 2 AAA ATPase domain CM_1 PF07736.11 CBZ38540.1 - 0.011 16.1 1.2 0.39 11.1 0.1 3.8 2 1 1 3 3 3 0 Chorismate mutase type I AAA_24 PF13479.6 CBZ38540.1 - 0.022 14.5 0.0 6.1 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CBZ38540.1 - 0.054 14.0 5.0 1.4 9.5 0.0 4.9 6 0 0 6 6 2 0 AAA domain AAA_14 PF13173.6 CBZ38540.1 - 0.065 13.3 0.0 9.7 6.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CBZ38540.1 - 0.14 12.3 2.9 2 8.6 0.0 3.6 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 CBZ38540.1 - 0.84 9.9 9.4 34 4.6 0.0 5.0 5 0 0 5 5 3 0 AAA domain Filament PF00038.21 CBZ38540.1 - 2.9 7.4 38.1 0.12 11.9 5.9 4.2 3 0 0 3 3 3 0 Intermediate filament protein Fib_alpha PF08702.10 CBZ38540.1 - 4.9 7.3 19.3 0.08 13.1 0.7 4.4 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family S10_plectin PF03501.15 CBZ38543.1 - 3.3e-35 120.0 0.0 3.9e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain S10_plectin PF03501.15 CBZ38544.1 - 4.3e-35 119.7 0.0 5.1e-35 119.4 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain WD40 PF00400.32 CBZ38545.1 - 4e-12 46.5 13.6 1.3e-07 32.2 0.5 6.9 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ38545.1 - 1.1e-08 35.3 0.0 0.37 11.1 0.0 5.1 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CBZ38545.1 - 2.5e-05 23.5 0.0 0.0074 15.4 0.1 4.1 5 0 0 5 5 5 1 Coatomer WD associated region Clathrin PF00637.20 CBZ38545.1 - 0.0003 20.7 1.7 0.1 12.5 0.0 3.6 2 1 2 4 4 4 2 Region in Clathrin and VPS TPR_7 PF13176.6 CBZ38545.1 - 0.0025 17.7 1.3 0.9 9.7 0.0 4.3 5 1 0 5 5 4 1 Tetratricopeptide repeat Nic96 PF04097.14 CBZ38545.1 - 0.005 15.3 0.0 0.0081 14.7 0.0 1.3 1 0 0 1 1 1 1 Nup93/Nic96 DUF2802 PF10975.8 CBZ38545.1 - 0.0062 16.6 0.1 0.038 14.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2802) TPR_MalT PF17874.1 CBZ38545.1 - 0.034 13.5 0.2 0.09 12.1 0.2 1.7 1 0 0 1 1 1 0 MalT-like TPR region TPR_14 PF13428.6 CBZ38545.1 - 0.42 11.6 9.5 34 5.6 0.5 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ38545.1 - 1.3 9.3 10.5 17 5.8 0.2 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-RING_6 PF14835.6 CBZ38545.1 - 8.4 6.4 14.8 0.14 12.1 0.8 3.6 4 0 0 4 4 4 0 zf-RING of BARD1-type protein LOH1CR12 PF10158.9 CBZ38546.1 - 0.089 12.8 1.8 0.2 11.7 1.8 1.5 1 0 0 1 1 1 0 Tumour suppressor protein Thymidylat_synt PF00303.19 CBZ38546.1 - 0.17 11.0 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Thymidylate synthase CLAMP PF14769.6 CBZ38549.1 - 2.2e-30 105.0 1.8 4.9e-30 103.9 1.6 1.7 1 1 1 2 2 2 1 Flagellar C1a complex subunit C1a-32 Tsi6 PF18660.1 CBZ38549.1 - 0.061 13.4 0.1 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 Tsi6 Ribonuclease_3 PF00636.26 CBZ38550.1 - 0.0043 17.7 0.0 0.014 16.0 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain WSD PF15613.6 CBZ38551.1 - 1.2e-08 35.3 3.1 1.4e-08 35.1 0.0 2.9 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif BUD22 PF09073.10 CBZ38551.1 - 0.00024 20.6 24.0 0.0031 16.9 7.3 2.5 2 0 0 2 2 2 2 BUD22 DDT PF02791.17 CBZ38551.1 - 0.0063 16.8 0.3 0.0063 16.8 0.3 2.3 3 0 0 3 3 3 1 DDT domain AC_N PF16214.5 CBZ38551.1 - 1.7 7.7 5.0 4.5 6.3 5.0 1.7 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Ribosomal_L24e PF01246.20 CBZ38552.1 - 1.6e-05 25.0 0.1 1.6e-05 25.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e DUF4189 PF13827.6 CBZ38554.1 - 0.043 14.3 1.5 0.059 13.9 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4189) HORMA PF02301.18 CBZ38555.1 - 1e-48 165.7 0.0 1.3e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 HORMA domain SPEG_u2 PF16650.5 CBZ38556.1 - 1.2 9.3 4.1 18 5.6 0.2 2.5 2 0 0 2 2 2 0 Unstructured region on SPEG complex protein YqhG PF11079.8 CBZ38557.1 - 0.1 11.5 0.0 12 4.7 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein YqhG of unknown function 3HCDH_N PF02737.18 CBZ38558.1 - 3.7e-57 193.1 1.6 4.6e-57 192.8 1.6 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CBZ38558.1 - 3.9e-34 117.1 0.0 1.8e-33 115.1 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CBZ38558.1 - 0.014 15.6 1.0 0.055 13.6 1.0 1.9 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 CBZ38558.1 - 0.023 13.9 0.2 0.033 13.4 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ38558.1 - 0.033 14.7 0.1 0.09 13.3 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Memo PF01875.17 CBZ38560.1 - 9.2e-61 205.4 0.0 1.2e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein AChE_tetra PF08674.10 CBZ38560.1 - 0.047 13.4 5.0 0.06 13.0 0.4 2.9 3 0 0 3 3 3 0 Acetylcholinesterase tetramerisation domain CorA PF01544.18 CBZ38561.1 - 8e-05 22.1 0.1 0.00024 20.5 0.1 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein COQ7 PF03232.13 CBZ38563.1 - 0.035 13.9 0.1 0.045 13.5 0.1 1.1 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Glyco_transf_22 PF03901.17 CBZ38564.1 - 8.2e-66 222.9 26.2 9.8e-66 222.7 26.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PP2C PF00481.21 CBZ38567.1 - 6.9e-08 32.4 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Agenet PF05641.12 CBZ38567.1 - 0.062 13.8 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Agenet domain DUF5393 PF17371.2 CBZ38568.1 - 0 1131.1 14.5 0 1130.8 14.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5393) S4 PF01479.25 CBZ38569.1 - 2.7e-13 49.4 0.3 5.8e-13 48.3 0.3 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 CBZ38569.1 - 1.1e-07 32.7 0.2 2.3e-07 31.6 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain TyrRSs_C PF16714.5 CBZ38569.1 - 0.02 14.7 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Glycolytic PF00274.19 CBZ38570.1 - 1.4e-141 471.3 0.0 1.6e-141 471.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I KfrA_N PF11740.8 CBZ38572.1 - 0.083 13.6 6.0 1.8 9.3 1.0 2.4 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term DUF3094 PF11293.8 CBZ38572.1 - 0.17 11.6 3.4 0.73 9.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) SIP1 PF04938.12 CBZ38573.1 - 8.8e-05 22.3 0.0 0.00027 20.7 0.0 2.1 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) BILBO1_N PF18281.1 CBZ38574.1 - 3.1e-29 101.2 0.2 5.8e-29 100.4 0.2 1.4 1 0 0 1 1 1 1 BILBO1 N-terminal domain DUF1682 PF07946.14 CBZ38574.1 - 1.5 8.0 8.2 86 2.2 9.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) DnaJ PF00226.31 CBZ38576.1 - 1e-06 28.7 0.0 2.7e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 DnaJ domain MerC PF03203.14 CBZ38576.1 - 0.044 14.2 0.2 0.068 13.6 0.2 1.3 1 0 0 1 1 1 0 MerC mercury resistance protein DUF3491 PF11996.8 CBZ38576.1 - 0.16 9.7 0.0 0.21 9.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) NARP1 PF12569.8 CBZ38577.1 - 4.1e-85 286.6 13.7 3.7e-81 273.6 9.3 2.7 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CBZ38577.1 - 7.3e-14 50.7 12.8 0.00023 21.0 0.0 7.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ38577.1 - 3.3e-12 45.7 3.9 9.5e-05 22.1 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ38577.1 - 9.4e-10 37.9 1.9 0.017 15.3 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ38577.1 - 1.8e-08 34.2 1.2 0.41 11.1 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38577.1 - 4.1e-08 33.4 23.6 0.52 11.3 0.0 8.5 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ38577.1 - 6.6e-08 33.0 6.6 0.0025 18.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ38577.1 - 9.5e-07 28.9 8.2 0.00055 20.0 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38577.1 - 5.5e-06 26.0 1.5 0.055 13.2 0.0 5.3 4 1 1 5 5 5 1 TPR repeat TPR_7 PF13176.6 CBZ38577.1 - 0.00016 21.5 6.4 3.9 7.7 0.0 6.4 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38577.1 - 0.00022 21.5 15.4 0.2 12.0 0.0 5.7 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ38577.1 - 0.00056 20.5 21.2 0.9 10.2 4.3 6.7 6 1 2 8 8 8 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ38577.1 - 0.0041 17.2 1.0 21 5.3 0.0 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CBZ38577.1 - 0.035 14.3 16.4 0.65 10.3 0.0 5.4 4 1 2 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CBZ38577.1 - 0.045 13.6 2.9 4.8 7.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1771 PF08590.10 CBZ38577.1 - 0.76 10.2 8.0 1.6 9.2 3.7 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1771) zf-PARP PF00645.18 CBZ38578.1 - 5.4e-19 68.8 0.8 1.1e-18 67.9 0.8 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.9 CBZ38578.1 - 9.5e-09 35.1 4.2 1.6e-08 34.3 4.2 1.4 1 0 0 1 1 1 1 PBZ domain ADK PF00406.22 CBZ38579.1 - 5.1e-42 143.5 0.0 9.2e-42 142.7 0.0 1.4 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CBZ38579.1 - 7.1e-25 88.0 0.0 4.5e-24 85.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CBZ38579.1 - 1.9e-11 44.6 0.1 6.2e-11 43.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CBZ38579.1 - 6.7e-05 23.1 0.1 0.00015 21.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 CBZ38579.1 - 0.0033 17.2 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase AAA PF00004.29 CBZ38579.1 - 0.0034 17.8 0.0 0.013 16.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 CBZ38579.1 - 0.0044 17.3 0.1 0.081 13.2 0.0 2.5 2 1 1 3 3 3 1 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 CBZ38579.1 - 0.0069 15.7 0.0 0.051 12.8 0.0 2.2 2 1 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.17 CBZ38579.1 - 0.025 14.3 0.5 1.8 8.2 0.0 2.9 2 1 1 3 3 3 0 Thymidylate kinase AAA_24 PF13479.6 CBZ38579.1 - 0.036 13.8 0.3 5.2 6.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CBZ38579.1 - 0.046 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CBZ38579.1 - 0.077 12.9 0.1 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain dNK PF01712.19 CBZ38579.1 - 0.13 12.2 1.0 5.7 6.7 0.0 2.9 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA PF00004.29 CBZ38580.1 - 7.1e-96 317.7 0.0 6e-47 159.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ38580.1 - 6.6e-27 93.1 8.4 2.1e-13 49.8 0.3 3.2 3 1 0 3 3 2 2 AAA+ lid domain CDC48_N PF02359.18 CBZ38580.1 - 2.5e-21 75.7 0.2 1.1e-20 73.6 0.1 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CBZ38580.1 - 1e-13 51.3 0.0 1e-05 25.3 0.0 2.7 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ38580.1 - 2.1e-12 47.7 0.2 0.00044 20.7 0.0 4.0 2 2 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 CBZ38580.1 - 3.8e-12 46.6 0.0 2.3e-06 27.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CBZ38580.1 - 3.6e-11 43.4 0.0 1.1e-05 25.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.17 CBZ38580.1 - 2e-10 40.3 0.0 4.6e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 CBZ38580.1 - 2.2e-10 40.6 0.1 6.7e-05 22.9 0.0 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CBZ38580.1 - 2.9e-09 37.3 0.4 0.037 14.3 0.0 3.9 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 CBZ38580.1 - 9.8e-09 34.9 0.1 0.00037 19.8 0.1 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 CBZ38580.1 - 1.5e-07 31.5 0.0 0.0047 17.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CBZ38580.1 - 1.6e-07 31.9 0.0 0.015 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CBZ38580.1 - 2e-07 31.4 0.0 0.0049 17.2 0.0 2.9 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 CBZ38580.1 - 4.6e-07 29.4 0.2 0.031 13.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CBZ38580.1 - 4.5e-06 26.5 0.0 0.074 12.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 CBZ38580.1 - 1.5e-05 25.5 0.0 0.054 14.0 0.0 3.1 2 1 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 CBZ38580.1 - 1.5e-05 24.6 0.3 1.1 8.9 0.0 3.5 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.6 CBZ38580.1 - 1.6e-05 25.4 0.0 0.11 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 CBZ38580.1 - 1.8e-05 24.7 0.1 0.00056 19.9 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Zeta_toxin PF06414.12 CBZ38580.1 - 1.9e-05 24.1 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 CBZ38580.1 - 2e-05 24.9 0.0 0.24 11.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain ATPase_2 PF01637.18 CBZ38580.1 - 2.5e-05 24.3 0.2 0.33 10.8 0.1 3.0 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 CBZ38580.1 - 3.1e-05 23.9 0.0 0.039 13.8 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein Parvo_NS1 PF01057.17 CBZ38580.1 - 3.6e-05 23.0 0.0 0.056 12.5 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase PF06745.13 CBZ38580.1 - 5.3e-05 22.7 0.2 1.5 8.1 0.0 3.4 3 0 0 3 3 3 1 KaiC NACHT PF05729.12 CBZ38580.1 - 5.7e-05 23.1 0.1 0.19 11.6 0.0 3.1 3 1 0 3 3 3 1 NACHT domain AAA_24 PF13479.6 CBZ38580.1 - 5.9e-05 22.9 0.0 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CBZ38580.1 - 0.00011 22.0 0.0 0.68 9.6 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 CBZ38580.1 - 0.00011 22.1 0.0 0.64 10.0 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 CBZ38580.1 - 0.00013 21.8 0.0 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 CBZ38580.1 - 0.00016 21.2 0.0 0.49 9.9 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_3 PF07726.11 CBZ38580.1 - 0.00034 20.5 0.0 0.96 9.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 CBZ38580.1 - 0.00072 19.6 0.0 0.066 13.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 CBZ38580.1 - 0.00075 18.8 0.0 0.98 8.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activ_2 PF14532.6 CBZ38580.1 - 0.0011 19.1 0.0 0.65 10.1 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 CBZ38580.1 - 0.0025 17.3 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 CBZ38580.1 - 0.0031 16.8 0.0 0.87 8.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CBZ38580.1 - 0.008 16.1 0.9 10 6.0 0.0 3.9 3 1 1 4 4 4 0 NTPase Rad17 PF03215.15 CBZ38580.1 - 0.0093 15.9 0.0 1.9 8.4 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain Molydop_binding PF01568.21 CBZ38580.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Cytidylate_kin2 PF13189.6 CBZ38580.1 - 0.018 15.2 0.4 1.3 9.2 0.0 2.6 3 0 0 3 3 2 0 Cytidylate kinase-like family DUF815 PF05673.13 CBZ38580.1 - 0.022 13.9 0.0 5.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 CBZ38580.1 - 0.034 13.9 0.0 5.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_11 PF13086.6 CBZ38580.1 - 0.045 13.5 0.0 12 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CBZ38580.1 - 0.047 13.4 0.0 7.3 6.4 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.29 CBZ38580.1 - 0.056 13.2 0.2 7.3 6.3 0.0 3.4 4 0 0 4 4 4 0 DEAD/DEAH box helicase AAA_19 PF13245.6 CBZ38580.1 - 0.057 13.8 2.6 9 6.6 0.1 3.2 3 1 0 4 4 3 0 AAA domain SKI PF01202.22 CBZ38580.1 - 0.059 13.5 0.1 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_23 PF13476.6 CBZ38580.1 - 0.067 13.7 0.1 24 5.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CBZ38580.1 - 0.072 12.3 0.2 3.3 6.8 0.0 3.1 2 2 2 4 4 4 0 KAP family P-loop domain Zot PF05707.12 CBZ38580.1 - 0.077 12.6 0.0 1.1 8.8 0.0 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_30 PF13604.6 CBZ38580.1 - 0.085 12.6 0.1 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 CBZ38580.1 - 0.11 12.4 0.0 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein TEX19 PF15553.6 CBZ38580.1 - 0.17 11.8 0.1 0.31 11.0 0.1 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 AFG1_ATPase PF03969.16 CBZ38580.1 - 0.24 10.3 1.0 11 4.8 0.0 2.5 3 0 0 3 3 2 0 AFG1-like ATPase Trypsin_2 PF13365.6 CBZ38581.1 - 8.1e-06 26.8 0.1 1.2e-05 26.2 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain DUF755 PF05501.11 CBZ38582.1 - 0.034 14.4 5.6 0.11 12.8 5.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF755) ARL2_Bind_BART PF11527.8 CBZ38584.1 - 3.1e-32 111.1 1.1 6.6e-32 110.1 1.1 1.6 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART UIM PF02809.20 CBZ38584.1 - 0.0028 17.4 0.3 0.0028 17.4 0.3 4.1 4 0 0 4 4 4 1 Ubiquitin interaction motif IL15 PF02372.15 CBZ38584.1 - 0.068 13.2 1.3 2.1 8.4 0.2 2.5 2 0 0 2 2 2 0 Interleukin 15 DZR PF12773.7 CBZ38585.1 - 8.2 6.5 127.1 0.22 11.6 8.0 9.9 5 3 3 8 8 8 0 Double zinc ribbon zf-RanBP PF00641.18 CBZ38586.1 - 2.4e-19 68.3 80.8 6.7e-09 34.9 2.7 9.5 9 0 0 9 9 9 7 Zn-finger in Ran binding protein and others DZR PF12773.7 CBZ38586.1 - 3e-05 24.0 66.8 0.002 18.1 6.3 6.9 4 3 2 6 6 6 6 Double zinc ribbon EF1_GNE PF00736.19 CBZ38587.1 - 1.4e-26 92.5 1.0 2.2e-26 91.8 1.0 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DUF3752 PF12572.8 CBZ38587.1 - 0.0042 17.6 1.0 0.006 17.1 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) T2SSC PF11356.8 CBZ38587.1 - 0.18 11.7 2.2 0.29 11.0 2.2 1.3 1 0 0 1 1 1 0 Type II secretion system protein C UBA2_C PF16195.5 CBZ38587.1 - 0.19 12.4 7.1 0.34 11.6 7.1 1.4 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Chorein_N PF12624.7 CBZ38588.1 - 4.6e-25 88.0 0.2 3.6e-11 43.2 0.0 2.7 2 0 0 2 2 2 2 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 CBZ38588.1 - 4.7e-15 55.8 0.1 1e-08 35.2 0.0 2.3 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CBZ38588.1 - 3.7e-07 30.2 0.6 9.8e-07 28.8 0.6 1.8 1 1 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal DUF5582 PF17819.1 CBZ38589.1 - 0.0013 19.1 0.5 0.0025 18.3 0.5 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5582) DUF4400 PF14348.6 CBZ38589.1 - 0.13 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) ERM PF00769.19 CBZ38590.1 - 0.0025 17.7 0.4 0.004 17.0 0.4 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Kelch_4 PF13418.6 CBZ38591.1 - 4.2e-18 65.1 0.0 1.1e-06 28.6 0.0 5.1 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ38591.1 - 8.1e-17 60.5 1.5 7.4e-08 31.9 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CBZ38591.1 - 4.6e-12 45.8 2.2 0.00028 21.1 0.0 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CBZ38591.1 - 5.3e-11 42.0 0.5 1.7e-05 24.6 0.0 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CBZ38591.1 - 1.2e-10 41.4 0.3 0.0018 18.5 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CBZ38591.1 - 3e-08 33.4 7.7 0.00077 19.4 0.0 4.1 4 0 0 4 4 4 2 Kelch motif DUF4515 PF14988.6 CBZ38595.1 - 0.014 15.2 1.2 0.02 14.8 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) DUF4795 PF16043.5 CBZ38595.1 - 0.023 14.3 0.8 0.029 14.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4392 PF14336.6 CBZ38595.1 - 0.028 13.9 0.2 0.035 13.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Med30 PF11315.8 CBZ38595.1 - 0.055 13.7 0.5 0.11 12.7 0.5 1.5 1 1 0 1 1 1 0 Mediator complex subunit 30 AAA_23 PF13476.6 CBZ38595.1 - 0.064 13.7 1.3 0.08 13.4 1.3 1.1 1 0 0 1 1 1 0 AAA domain FliS PF02561.14 CBZ38595.1 - 0.075 13.3 0.5 0.11 12.8 0.5 1.2 1 0 0 1 1 1 0 Flagellar protein FliS Spectrin PF00435.21 CBZ38595.1 - 0.12 12.9 3.5 0.17 12.4 0.5 2.3 1 1 1 2 2 2 0 Spectrin repeat Nucleocap_ssRNA PF11128.8 CBZ38595.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Plant viral coat protein nucleocapsid Pkinase PF00069.25 CBZ38596.1 - 5.4e-56 189.9 0.0 8.3e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38596.1 - 6e-35 120.8 0.0 9.5e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ38596.1 - 6e-06 25.8 0.0 1.5e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like PH PF00169.29 CBZ38596.1 - 0.00016 22.1 0.3 0.00057 20.4 0.3 1.9 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 CBZ38596.1 - 0.00058 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 CBZ38596.1 - 0.028 14.8 0.1 0.11 12.9 0.1 2.0 2 1 0 2 2 2 0 Pleckstrin homology domain PH_4 PF15404.6 CBZ38596.1 - 0.042 13.6 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase_fungal PF17667.1 CBZ38596.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CBZ38597.1 - 1.8e-54 184.9 0.0 2.4e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38597.1 - 1.5e-34 119.5 0.0 2.2e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ38597.1 - 1.9e-06 27.4 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 CBZ38597.1 - 4.2e-06 27.2 0.0 9.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 CBZ38597.1 - 0.023 13.5 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ELMO_CED12 PF04727.13 CBZ38598.1 - 4.5e-35 121.4 0.0 6.2e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 ELMO/CED-12 family zf-B_box PF00643.24 CBZ38599.1 - 4e-08 33.3 6.7 4e-08 33.3 6.7 3.7 5 0 0 5 5 5 2 B-box zinc finger Baculo_PEP_C PF04513.12 CBZ38599.1 - 0.012 15.6 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus LRR_4 PF12799.7 CBZ38600.1 - 8.4e-21 73.7 8.6 2.9e-05 24.3 0.9 5.9 3 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ38600.1 - 1.8e-17 62.9 6.8 2.7e-07 30.2 0.1 4.6 4 0 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CBZ38600.1 - 1.7e-08 34.2 1.0 0.00058 19.4 0.5 2.6 1 1 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CBZ38600.1 - 0.0052 16.7 11.0 13 6.2 0.0 6.4 6 0 0 6 6 6 1 Leucine Rich repeat LRR_5 PF13306.6 CBZ38600.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 CBZ38600.1 - 0.11 13.1 14.6 12 6.9 0.2 7.3 8 2 0 8 8 8 0 Leucine Rich Repeat DUF4407 PF14362.6 CBZ38601.1 - 0.00013 21.5 24.9 0.001 18.5 16.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) DUF2408 PF10303.9 CBZ38601.1 - 0.14 12.8 13.5 0.19 12.3 4.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) AAA_23 PF13476.6 CBZ38601.1 - 4 7.9 16.0 33 4.9 11.5 2.4 2 0 0 2 2 2 0 AAA domain Spc7 PF08317.11 CBZ38601.1 - 4.9 5.9 32.0 2.4 7.0 5.0 2.4 2 1 0 2 2 2 0 Spc7 kinetochore protein FAM184 PF15665.5 CBZ38601.1 - 9.4 6.0 34.0 0.15 11.8 0.7 2.7 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B Rnk_N PF14760.6 CBZ38602.1 - 0.056 13.9 2.3 0.24 11.9 0.2 2.9 2 0 0 2 2 2 0 Rnk N-terminus STAG PF08514.11 CBZ38603.1 - 1.2e-20 73.5 0.6 1.2e-20 73.5 0.6 2.4 2 0 0 2 2 2 1 STAG domain Proteasome PF00227.26 CBZ38605.1 - 3.5e-56 189.7 0.1 4.4e-56 189.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CBZ38605.1 - 2.6e-13 49.4 0.0 7.3e-13 47.9 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature zf-CCHC PF00098.23 CBZ38606.1 - 2.4e-42 141.2 41.1 8e-10 38.3 3.1 5.1 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_3 PF13917.6 CBZ38606.1 - 2.4e-14 53.0 26.6 0.0041 17.0 0.8 5.0 1 1 4 5 5 5 5 Zinc knuckle zf-CCHC_4 PF14392.6 CBZ38606.1 - 4.9e-09 35.8 27.0 0.092 12.5 1.0 5.0 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_6 PF15288.6 CBZ38606.1 - 7.9e-06 25.6 28.9 0.073 12.9 0.6 5.1 2 2 3 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 CBZ38606.1 - 0.017 14.9 31.4 0.37 10.7 2.1 5.3 5 0 0 5 5 5 0 Zinc knuckle HscB_4_cys PF18256.1 CBZ38606.1 - 0.084 12.7 25.7 9.5 6.1 1.1 5.5 5 0 0 5 5 5 0 Co-chaperone HscB tetracysteine metal binding motif Dermcidin PF15291.6 CBZ38606.1 - 0.12 13.0 0.4 2.5 8.7 0.1 2.2 1 1 1 2 2 2 0 Dermcidin, antibiotic peptide zf-CCHC_5 PF14787.6 CBZ38606.1 - 0.36 10.6 31.0 2.9 7.7 0.5 5.1 5 0 0 5 5 5 0 GAG-polyprotein viral zinc-finger TRAF6_Z2 PF18048.1 CBZ38606.1 - 0.67 10.1 12.2 19 5.4 0.1 5.2 5 1 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 zf-CCHC PF00098.23 CBZ38607.1 - 2.2e-14 52.8 11.3 1.3e-08 34.6 2.0 2.1 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CBZ38607.1 - 4.4e-05 23.4 5.2 0.0044 16.9 0.7 2.0 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 CBZ38607.1 - 0.0014 18.5 7.4 0.035 13.9 1.9 2.1 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 CBZ38607.1 - 0.0026 17.4 6.5 0.1 12.4 0.6 2.0 2 0 0 2 2 2 2 Zinc knuckle Ntox16 PF15523.6 CBZ38607.1 - 0.013 15.8 4.2 0.84 9.9 0.4 2.0 1 1 1 2 2 2 0 Novel toxin 16 NinD PF17466.2 CBZ38607.1 - 0.032 14.3 3.4 0.9 9.7 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function HscB_4_cys PF18256.1 CBZ38607.1 - 0.039 13.8 5.1 2.1 8.2 0.9 2.5 2 1 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif DZR PF12773.7 CBZ38607.1 - 0.13 12.4 6.0 0.21 11.6 6.0 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 CBZ38607.1 - 0.14 11.6 7.4 1.3 8.5 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain DUF1815 PF08844.10 CBZ38607.1 - 0.48 10.4 5.6 2.8 8.0 0.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1815) zf-C2HC_2 PF13913.6 CBZ38607.1 - 0.49 10.4 7.1 2.8 8.0 0.2 2.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_10 PF16588.5 CBZ38607.1 - 0.58 9.9 9.1 1.8 8.4 1.5 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger Clathrin PF00637.20 CBZ38608.1 - 1.9e-161 530.3 41.3 4.4e-27 94.7 1.5 8.9 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CBZ38608.1 - 2e-18 66.0 0.0 1e-17 63.8 0.0 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.20 CBZ38608.1 - 6.2e-09 35.7 0.2 0.16 12.4 0.0 4.7 5 0 0 5 5 5 3 Clathrin propeller repeat Clathrin-link PF09268.10 CBZ38608.1 - 6.6e-07 28.6 0.4 2.4e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_1 PF00515.28 CBZ38608.1 - 0.019 14.8 0.5 8.8 6.3 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ38608.1 - 0.051 13.6 4.3 29 5.0 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR PF01535.20 CBZ38608.1 - 0.1 12.9 0.3 77 3.9 0.0 4.8 3 0 0 3 3 3 0 PPR repeat Egg_lysin PF01303.17 CBZ38608.1 - 0.16 12.2 5.3 1.3 9.3 0.5 3.6 3 0 0 3 3 3 0 Egg lysin (Sperm-lysin) Dynein_heavy PF03028.15 CBZ38608.1 - 0.16 12.1 0.7 1.9 8.6 0.3 3.0 2 0 0 2 2 2 0 Dynein heavy chain region D6 P-loop domain Mic1 PF07035.12 CBZ38608.1 - 0.26 11.0 0.0 0.26 11.0 0.0 4.5 5 1 1 6 6 6 0 Colon cancer-associated protein Mic1-like zf-CCHC PF00098.23 CBZ38609.1 - 2.6e-39 131.6 49.3 1.8e-07 30.9 2.3 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 CBZ38609.1 - 2e-08 34.1 33.8 0.005 16.8 0.8 5.0 2 1 3 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 CBZ38609.1 - 4e-08 32.9 50.7 9.4e-05 22.2 2.5 6.3 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.6 CBZ38609.1 - 3.4e-06 26.7 32.8 0.12 12.1 1.6 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.6 CBZ38609.1 - 6.8e-06 25.7 39.6 0.0021 17.7 0.8 5.6 4 2 2 6 6 6 5 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 CBZ38610.1 - 2.7e-74 242.2 87.9 4.1e-09 36.1 2.1 9.2 9 0 0 9 9 9 9 Zinc knuckle zf-CCHC_3 PF13917.6 CBZ38610.1 - 7.2e-27 93.1 53.4 0.00024 21.0 0.9 9.1 3 2 6 9 9 9 9 Zinc knuckle zf-CCHC_2 PF13696.6 CBZ38610.1 - 2.8e-11 43.0 65.7 0.00019 21.2 1.2 9.4 9 0 0 9 9 9 5 Zinc knuckle zf-CCHC_5 PF14787.6 CBZ38610.1 - 1.2e-08 34.5 60.5 0.21 11.3 0.7 9.2 9 0 0 9 9 9 9 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 CBZ38610.1 - 9.8e-08 31.6 53.9 1.1 9.1 0.5 9.1 9 0 0 9 9 9 9 Zinc knuckle zf-CCHC_6 PF15288.6 CBZ38610.1 - 0.00036 20.3 67.0 0.1 12.4 1.2 9.2 8 1 1 9 9 9 7 Zinc knuckle TRAF6_Z2 PF18048.1 CBZ38610.1 - 0.0083 16.2 31.5 6 7.1 0.2 8.9 9 0 0 9 9 9 1 TNF receptor-associated factor 6 zinc finger 2 Ntox16 PF15523.6 CBZ38610.1 - 0.044 14.0 47.1 3.3 8.0 0.5 8.4 7 1 1 8 8 8 0 Novel toxin 16 zf-ribbon_3 PF13248.6 CBZ38610.1 - 0.19 11.2 60.1 0.12 11.9 3.3 10.5 10 0 0 10 10 10 0 zinc-ribbon domain Hyd_WA PF06462.12 CBZ38610.1 - 9.6 6.3 14.0 37 4.4 0.1 6.0 7 0 0 7 7 7 0 Propeller Proteasome PF00227.26 CBZ38611.1 - 4.5e-48 163.3 0.2 5.5e-48 163.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit PseudoU_synth_2 PF00849.22 CBZ38612.1 - 1.2e-06 28.7 0.0 2.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 CBZ38612.1 - 4.2e-06 26.4 0.0 2.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 S4 domain Q_salvage PF10343.9 CBZ38613.1 - 6.5e-17 62.0 0.0 2.7e-16 60.0 0.0 1.9 3 0 0 3 3 3 1 Potential Queuosine, Q, salvage protein family Ank PF00023.30 CBZ38613.1 - 0.058 13.9 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat CAAD PF14159.6 CBZ38613.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Peptidase_M76 PF09768.9 CBZ38615.1 - 1.1e-56 191.3 0.5 1.5e-56 190.8 0.5 1.2 1 0 0 1 1 1 1 Peptidase M76 family HTH_30 PF13556.6 CBZ38615.1 - 0.0093 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 PucR C-terminal helix-turn-helix domain GPI2 PF06432.11 CBZ38617.1 - 7.9e-68 228.9 12.9 9.2e-68 228.7 12.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Beach PF02138.18 CBZ38618.1 - 1.1e-107 359.6 0.0 1.5e-107 359.1 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CBZ38618.1 - 2.8e-22 78.7 0.0 5.1e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 CBZ38618.1 - 5.5e-05 23.4 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 CBZ38618.1 - 0.039 14.8 0.1 1.8 9.5 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat Sec34 PF04136.15 CBZ38619.1 - 5.8e-12 45.7 1.2 5.8e-12 45.7 1.2 2.0 2 0 0 2 2 2 1 Sec34-like family MerR-DNA-bind PF09278.11 CBZ38619.1 - 0.55 10.8 3.6 5.7 7.6 0.1 3.2 2 0 0 2 2 2 0 MerR, DNA binding GAF PF01590.26 CBZ38620.1 - 0.024 15.3 1.0 6.1 7.5 0.1 3.7 3 1 0 3 3 3 0 GAF domain Herpes_IE2_3 PF03361.14 CBZ38620.1 - 0.059 13.3 0.6 0.88 9.4 0.1 2.4 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 Aldedh PF00171.22 CBZ38622.1 - 5.8e-165 549.3 0.1 6.6e-165 549.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3253 PF11625.8 CBZ38622.1 - 0.0066 16.6 0.2 0.017 15.3 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) DUF1487 PF07368.11 CBZ38622.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) TPR_2 PF07719.17 CBZ38624.1 - 5.4e-15 54.2 17.5 0.0019 18.2 0.1 9.6 10 1 1 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ38624.1 - 1.3e-14 53.3 7.4 0.00086 19.0 0.0 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ38624.1 - 1.7e-10 40.9 14.7 4.5e-06 26.7 0.3 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38624.1 - 2.3e-09 36.8 5.8 0.077 12.7 0.0 6.4 6 1 1 7 7 7 4 TPR repeat TPR_8 PF13181.6 CBZ38624.1 - 1.9e-08 33.8 2.0 2.4 8.6 0.1 7.4 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ38624.1 - 8.4e-08 32.6 21.9 0.13 12.7 0.2 7.2 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38624.1 - 4.8e-07 30.0 16.3 0.029 14.7 0.5 6.6 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ38624.1 - 6.4e-07 29.9 17.3 0.0088 16.7 0.1 7.6 9 1 1 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ38624.1 - 1.2e-06 28.5 1.1 2 9.0 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ38624.1 - 0.00068 19.5 17.4 0.092 12.8 0.1 6.6 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38624.1 - 0.001 19.7 28.1 7.6 7.6 1.1 9.6 5 3 5 10 10 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 CBZ38624.1 - 0.022 15.1 0.1 0.48 10.8 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 CBZ38624.1 - 0.068 12.4 3.2 4.7 6.3 0.0 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ38624.1 - 7.6 6.6 21.7 1.1 9.2 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat XRN_N PF03159.18 CBZ38625.1 - 1.4e-85 286.6 1.3 2.4e-85 285.8 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CBZ38625.1 - 1.1e-63 215.7 1.9 1.1e-63 215.7 1.9 2.8 2 1 0 2 2 2 1 Xrn1 helical domain TFIIA PF03153.13 CBZ38626.1 - 2.7 7.9 17.3 3.5 7.5 17.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MORN PF02493.20 CBZ38627.1 - 1.1e-54 179.1 87.8 5.4e-07 29.1 0.6 19.0 21 0 0 21 21 21 15 MORN repeat DUF3048_C PF17479.2 CBZ38627.1 - 0.057 13.8 0.5 0.057 13.8 0.5 4.5 5 1 0 5 5 5 0 Protein of unknown function (DUF3048) C-terminal domain Ras PF00071.22 CBZ38628.1 - 1.7e-13 50.5 0.0 2.7e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CBZ38628.1 - 1.1e-09 38.6 0.0 2.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CBZ38628.1 - 0.029 14.4 0.0 0.079 13.0 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CBZ38628.1 - 0.16 12.4 0.5 0.94 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 CBZ38630.1 - 1.2e-42 145.6 0.0 2.6e-42 144.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ38630.1 - 2.2e-23 82.7 0.0 1.9e-22 79.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CBZ38630.1 - 4.2e-15 55.7 0.0 8.8e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Menin PF05053.13 CBZ38630.1 - 2 6.7 10.5 3.2 6.0 10.5 1.2 1 0 0 1 1 1 0 Menin DEAD PF00270.29 CBZ38631.1 - 3e-46 157.4 0.1 1.5e-45 155.1 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ38631.1 - 4.3e-28 97.9 0.1 5.3e-27 94.4 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ38631.1 - 1.9e-05 24.7 0.0 7.3e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CBZ38631.1 - 0.00036 19.8 0.1 0.00089 18.5 0.0 1.5 1 1 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_S5_C PF03719.15 CBZ38632.1 - 2.4e-11 42.9 0.2 3.8e-11 42.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CBZ38632.1 - 2.3e-06 27.5 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF1918 PF08940.11 CBZ38632.1 - 0.14 11.8 0.0 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) MVP_shoulder PF11978.8 CBZ38633.1 - 1.7e-45 153.9 0.0 2.9e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 Shoulder domain Vault PF01505.18 CBZ38633.1 - 9.4e-28 96.1 0.0 1.1e-11 44.7 0.0 5.0 4 0 0 4 4 4 3 Major Vault Protein repeat domain Vault_2 PF17794.1 CBZ38633.1 - 4.5e-19 68.6 0.5 3.2e-12 46.6 0.1 3.1 2 1 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 CBZ38633.1 - 2.9e-15 56.1 0.0 1.4e-14 53.8 0.0 2.3 1 1 0 1 1 1 1 Major Vault Protein Repeat domain Vault_4 PF17796.1 CBZ38633.1 - 7.4e-13 48.4 0.0 4.4e-12 45.9 0.0 2.3 2 0 0 2 2 2 1 Major Vault Protein repeat domain Tfb4 PF03850.14 CBZ38633.1 - 0.073 12.6 4.7 0.12 11.8 4.7 1.3 1 0 0 1 1 1 0 Transcription factor Tfb4 CBF PF03914.17 CBZ38634.1 - 3.1e-28 98.9 0.3 3.1e-28 98.9 0.3 2.4 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.11 CBZ38634.1 - 7.2e-06 26.4 0.1 2.9e-05 24.5 0.1 2.1 1 0 0 1 1 1 1 Nucleolar complex-associated protein CENP-H PF05837.12 CBZ38634.1 - 0.83 10.1 5.8 2.6 8.5 2.7 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Cep57_MT_bd PF06657.13 CBZ38634.1 - 1.7 9.1 8.7 29 5.2 0.0 3.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 CBZ38634.1 - 3.4 7.5 6.5 13 5.6 6.5 1.9 1 0 0 1 1 1 0 Septum formation initiator MacB_PCD PF12704.7 CBZ38635.1 - 6.5 7.1 0.0 6.5 7.1 0.0 2.7 3 0 0 3 3 3 0 MacB-like periplasmic core domain GAS PF13851.6 CBZ38638.1 - 1.2e-56 191.2 30.0 1.2e-56 191.2 30.0 3.9 3 1 1 4 4 4 1 Growth-arrest specific micro-tubule binding Filament PF00038.21 CBZ38638.1 - 1.2 8.6 70.0 0.52 9.8 9.2 4.6 1 1 2 3 3 3 0 Intermediate filament protein PBECR1 PF18809.1 CBZ38638.1 - 2.5 8.8 11.4 0.27 11.9 3.8 3.1 2 1 1 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 MCU PF04678.13 CBZ38639.1 - 0.049 13.7 8.7 0.45 10.6 6.6 3.2 1 1 1 2 2 2 0 Mitochondrial calcium uniporter CLZ PF16526.5 CBZ38639.1 - 2.4 8.6 10.8 4.4 7.7 0.2 4.7 5 0 0 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ribosomal_L37ae PF01780.19 CBZ38640.1 - 9.2e-37 125.0 4.5 1e-36 124.9 4.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family C1_1 PF00130.22 CBZ38640.1 - 0.0022 17.8 2.3 0.0032 17.3 2.3 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_13 PF17977.1 CBZ38640.1 - 0.05 13.7 1.1 0.071 13.2 1.1 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CBZ38640.1 - 0.065 13.2 2.3 0.11 12.5 2.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain NOB1_Zn_bind PF08772.11 CBZ38640.1 - 0.16 12.2 3.8 0.43 10.8 0.6 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-C3HC4_3 PF13920.6 CBZ38641.1 - 1.3e-10 41.0 3.4 1.8e-10 40.5 3.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ38641.1 - 1.3e-10 41.0 5.9 2e-10 40.4 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ38641.1 - 2e-09 37.2 4.9 3.2e-09 36.5 4.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CBZ38641.1 - 2.7e-09 36.9 5.3 3.5e-09 36.5 3.1 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CBZ38641.1 - 4.1e-09 36.1 8.2 6.7e-09 35.4 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ38641.1 - 8.4e-09 35.6 9.1 1.3e-08 35.0 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CBZ38641.1 - 4.4e-07 29.8 5.7 6.7e-07 29.2 5.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CBZ38641.1 - 5.2e-07 29.7 6.9 8.8e-07 29.0 6.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CBZ38641.1 - 0.00025 21.3 7.8 0.00069 19.9 7.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CBZ38641.1 - 0.003 17.6 2.3 0.0059 16.6 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.11 CBZ38641.1 - 0.0084 16.1 2.0 0.013 15.5 2.0 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 CBZ38641.1 - 0.036 13.9 4.6 0.089 12.7 4.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CBZ38641.1 - 0.12 12.2 4.7 0.3 10.9 4.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain SPX PF03105.19 CBZ38641.1 - 0.16 11.9 2.3 0.25 11.2 2.3 1.2 1 0 0 1 1 1 0 SPX domain zf-RING_10 PF16685.5 CBZ38641.1 - 0.19 11.9 3.6 0.32 11.1 3.6 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 RINGv PF12906.7 CBZ38641.1 - 0.45 10.7 4.5 1.4 9.1 4.5 1.9 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 CBZ38641.1 - 0.66 9.6 6.8 1.2 8.9 6.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CBZ38641.1 - 2.3 8.0 7.4 1.3 8.9 4.1 2.2 2 0 0 2 2 2 0 RING-like zinc finger IBR PF01485.21 CBZ38641.1 - 2.4 8.4 8.8 1.6 9.0 6.8 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Nucleoside_tran PF01733.18 CBZ38642.1 - 2.7e-24 86.1 7.7 2.7e-24 86.1 7.7 2.1 2 1 0 2 2 2 1 Nucleoside transporter Ndc1_Nup PF09531.10 CBZ38642.1 - 5.7 5.5 9.6 0.21 10.3 2.0 2.1 2 1 0 2 2 2 0 Nucleoporin protein Ndc1-Nup MutS_V PF00488.21 CBZ38643.1 - 9.1e-55 185.6 0.9 9.7e-54 182.3 0.9 2.4 1 1 0 1 1 1 1 MutS domain V MutS_I PF01624.20 CBZ38643.1 - 1.1e-32 112.6 0.1 2.3e-32 111.6 0.1 1.6 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 CBZ38643.1 - 1.5e-32 113.4 0.6 3.6e-32 112.2 0.4 1.8 2 0 0 2 2 2 1 MutS domain III AAA_29 PF13555.6 CBZ38643.1 - 0.0002 21.1 1.0 0.031 14.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MutS_IV PF05190.18 CBZ38643.1 - 0.0035 17.7 0.0 0.0082 16.5 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV ABC_tran PF00005.27 CBZ38643.1 - 0.0044 17.5 0.1 0.017 15.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter TLD PF07534.16 CBZ38644.1 - 2.8e-21 76.2 0.1 3.4e-20 72.7 0.1 2.0 1 1 0 1 1 1 1 TLD PMM PF03332.13 CBZ38645.1 - 9.7e-101 336.1 0.8 1.1e-100 335.9 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CBZ38645.1 - 2.1e-06 27.7 0.0 4.8e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CBZ38645.1 - 6.6e-05 22.5 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase HAD_2 PF13419.6 CBZ38645.1 - 0.019 15.1 0.5 3.4 7.7 0.0 3.2 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase FliG_N PF14842.6 CBZ38645.1 - 0.044 14.3 0.0 0.097 13.2 0.0 1.5 1 0 0 1 1 1 0 FliG N-terminal domain Hydrolase PF00702.26 CBZ38645.1 - 0.29 11.4 0.7 3.3 7.9 0.5 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase 2OG-FeII_Oxy_2 PF13532.6 CBZ38646.1 - 3.2e-07 30.7 0.0 9.1e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CBZ38646.1 - 0.0037 17.7 0.0 0.0065 16.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.28 CBZ38647.1 - 8.5e-18 65.6 0.0 1.2e-17 65.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ipi1_N PF12333.8 CBZ38649.1 - 1 10.0 3.1 2 9.0 0.1 3.0 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation PHM7_cyt PF14703.6 CBZ38650.1 - 1.4 9.1 12.3 0.25 11.5 7.1 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Cpn60_TCP1 PF00118.24 CBZ38651.1 - 9.4e-85 285.1 15.3 1.4e-84 284.5 15.3 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn60_TCP1 PF00118.24 CBZ38652.1 - 1.2e-86 291.3 16.2 2.5e-86 290.3 16.2 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 CBZ38653.1 - 1.8e-08 34.9 5.9 0.031 15.1 0.5 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ALG3 PF05208.13 CBZ38654.1 - 3.2e-125 418.3 13.8 3.8e-125 418.0 13.8 1.0 1 0 0 1 1 1 1 ALG3 protein Metallophos PF00149.28 CBZ38655.1 - 3.6e-15 57.0 0.0 2.7e-10 41.1 0.0 2.6 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase DUF72 PF01904.18 CBZ38656.1 - 2.3e-29 103.1 0.1 2.3e-27 96.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function DUF72 TPR_2 PF07719.17 CBZ38657.1 - 4.6e-12 45.1 8.8 6.7e-07 29.0 0.7 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ38657.1 - 5.6e-09 35.4 6.6 1.1e-05 25.0 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CBZ38657.1 - 3.9e-07 29.8 0.9 0.00069 19.6 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38657.1 - 1.9e-06 27.5 2.5 0.00071 19.2 0.2 3.4 2 2 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 CBZ38657.1 - 3.2e-06 27.7 22.2 0.00016 22.3 3.7 3.9 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ38657.1 - 1.9e-05 24.4 1.4 0.0054 16.7 0.3 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38657.1 - 0.00039 21.0 2.8 0.00039 21.0 2.8 4.1 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38657.1 - 0.0032 17.7 5.9 0.016 15.4 1.7 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ38657.1 - 0.038 14.2 3.8 2.4 8.4 3.2 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ38657.1 - 0.044 14.4 0.4 1.1 10.1 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ38657.1 - 0.059 13.3 0.9 0.059 13.3 0.9 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat T2SSppdC PF12528.8 CBZ38657.1 - 0.072 13.9 1.1 0.18 12.6 1.1 1.6 1 0 0 1 1 1 0 Type II secretion prepilin peptidase dependent protein C TPR_19 PF14559.6 CBZ38657.1 - 0.31 11.6 8.0 0.33 11.5 4.4 2.8 2 2 0 2 2 2 0 Tetratricopeptide repeat SPA PF08616.10 CBZ38659.1 - 0.00098 19.1 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CBZ38659.1 - 0.0025 16.6 0.0 0.0081 14.9 0.0 1.8 2 0 0 2 2 2 1 Transport protein Avl9 Acetyltransf_10 PF13673.7 CBZ38660.1 - 7.9e-05 22.6 0.0 0.00075 19.4 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CBZ38660.1 - 0.00081 19.6 0.0 0.0027 17.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DnaJ PF00226.31 CBZ38661.1 - 5.5e-22 77.7 0.5 8.1e-22 77.1 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 CBZ38661.1 - 3e-07 30.6 0.5 2.6e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) YecR PF13992.6 CBZ38663.1 - 6.2 7.2 8.2 0.29 11.5 0.9 2.5 2 0 0 2 2 2 0 YecR-like lipoprotein DEAD PF00270.29 CBZ38664.1 - 1.9e-48 164.5 0.0 3.8e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ38664.1 - 1.8e-31 108.8 0.0 7e-30 103.6 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ38664.1 - 0.00011 22.2 0.0 0.0027 17.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CBZ38664.1 - 0.0014 18.4 0.0 0.082 12.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain ERCC3_RAD25_C PF16203.5 CBZ38664.1 - 0.0034 16.6 0.1 0.005 16.1 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2239 PF09998.9 CBZ38664.1 - 0.037 13.8 0.1 0.92 9.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2239) DUF2608 PF11019.8 CBZ38665.1 - 0.082 12.4 0.0 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) EMP24_GP25L PF01105.24 CBZ38666.1 - 3.3e-26 92.3 0.0 4.8e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dynein_light PF01221.18 CBZ38667.1 - 1.7e-22 79.5 0.0 2.3e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Alpha-amyl_C PF09071.10 CBZ38667.1 - 0.0049 16.7 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 Alpha-amylase, C terminal DUF3646 PF12362.8 CBZ38667.1 - 0.0072 16.6 0.0 0.012 15.9 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III gamma and tau subunits C terminal Methyltr_RsmB-F PF01189.17 CBZ38668.1 - 8.2e-30 103.9 0.0 8.4e-23 81.0 0.0 2.8 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CBZ38668.1 - 0.001 19.2 0.0 0.0029 17.7 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 CBZ38668.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Y_phosphatase PF00102.27 CBZ38669.1 - 1.3e-43 149.2 0.0 3.7e-43 147.8 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CBZ38669.1 - 7.4e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CBZ38669.1 - 0.14 12.1 0.3 0.52 10.2 0.1 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family PrkA PF06798.12 CBZ38670.1 - 0.053 13.1 2.7 0.17 11.5 0.5 2.5 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain Choline_transpo PF04515.12 CBZ38672.1 - 9.4e-67 225.5 31.6 9.4e-67 225.5 31.6 2.5 2 1 0 2 2 2 1 Plasma-membrane choline transporter BRCT_2 PF16589.5 CBZ38673.1 - 2.7e-07 30.9 0.0 0.00086 19.7 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CBZ38673.1 - 0.00082 19.7 0.1 0.19 12.1 0.0 3.2 2 2 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 CBZ38673.1 - 0.0027 17.7 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CBZ38673.1 - 0.015 15.2 0.0 3.4 7.7 0.0 2.8 3 0 0 3 3 3 0 twin BRCT domain Sec1 PF00995.23 CBZ38674.1 - 1.4e-98 331.7 0.0 1.6e-98 331.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family GCP_N_terminal PF17681.1 CBZ38675.1 - 1.6e-14 54.3 0.0 1.1e-13 51.5 0.0 2.3 3 0 0 3 3 3 1 Gamma tubulin complex component N-terminal MMR_HSR1_Xtn PF16897.5 CBZ38676.1 - 8.9e-42 141.4 0.0 1.8e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CBZ38676.1 - 1.1e-19 70.2 0.0 2.3e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CBZ38676.1 - 1.3e-19 70.4 0.0 2.9e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ38676.1 - 4e-09 36.2 0.0 1.3e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CBZ38676.1 - 0.0036 16.3 0.1 0.0096 14.9 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CBZ38676.1 - 0.059 13.4 0.2 2.5 8.1 0.0 2.4 1 1 1 2 2 2 0 Dynamin family Guanylate_kin PF00625.21 CBZ38677.1 - 5.3e-39 133.8 0.1 2.1e-23 83.0 0.0 3.0 2 1 0 2 2 2 2 Guanylate kinase AAA_33 PF13671.6 CBZ38677.1 - 2.3e-06 27.8 0.2 0.00063 19.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CBZ38677.1 - 0.00045 20.6 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CBZ38677.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 CBZ38677.1 - 0.0018 18.0 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CBZ38677.1 - 0.0035 17.6 0.0 0.007 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CBZ38677.1 - 0.0035 17.4 0.0 0.0076 16.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CBZ38677.1 - 0.0082 16.7 0.0 0.083 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CBZ38677.1 - 0.0089 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 CBZ38677.1 - 0.012 16.2 0.0 0.042 14.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 CBZ38677.1 - 0.02 15.3 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 CBZ38677.1 - 0.031 14.2 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 CBZ38677.1 - 0.031 14.5 0.1 0.17 12.1 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 CBZ38677.1 - 0.046 13.2 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 CBZ38677.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CBZ38677.1 - 0.079 13.0 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 CBZ38677.1 - 0.082 12.1 0.0 0.16 11.1 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.6 CBZ38677.1 - 0.09 12.5 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CBZ38677.1 - 0.091 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein dNK PF01712.19 CBZ38677.1 - 0.092 12.6 0.1 7.1 6.4 0.1 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_17 PF13207.6 CBZ38677.1 - 0.1 13.0 0.0 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_pol_N PF01194.17 CBZ38677.1 - 0.12 12.7 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA polymerases N / 8 kDa subunit AAA_23 PF13476.6 CBZ38677.1 - 0.26 11.8 0.0 0.57 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_1 PF00515.28 CBZ38679.1 - 6.8e-31 104.8 6.7 0.00037 20.2 0.0 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ38679.1 - 1.5e-28 96.5 12.0 0.00093 19.1 0.2 9.9 9 1 1 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38679.1 - 3.7e-23 80.9 5.6 7.3e-07 28.8 0.1 7.3 5 2 3 8 8 7 5 TPR repeat TPR_8 PF13181.6 CBZ38679.1 - 7e-22 75.8 1.2 0.0014 18.6 0.0 8.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ38679.1 - 6.5e-19 68.3 10.5 0.002 18.7 0.2 6.9 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ38679.1 - 2.6e-16 58.7 6.2 0.015 15.6 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38679.1 - 1.2e-15 57.5 18.9 1.7e-05 25.0 1.4 6.7 1 1 8 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ38679.1 - 1.2e-14 54.5 12.8 5.4e-06 26.8 0.1 5.8 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38679.1 - 3.3e-14 52.3 14.1 0.002 18.8 0.3 8.8 5 3 5 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 CBZ38679.1 - 4.2e-12 46.0 10.9 1.3e-06 28.5 0.1 5.2 3 1 2 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 CBZ38679.1 - 7.7e-12 45.0 7.7 2.1 9.2 0.1 8.5 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ38679.1 - 3.7e-10 39.9 19.9 0.0017 18.6 0.1 5.8 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CBZ38679.1 - 5.4e-07 29.2 12.5 0.53 10.4 0.1 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ38679.1 - 7.3e-07 28.9 9.6 0.0011 18.7 0.3 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 CBZ38679.1 - 3.8e-06 27.1 0.5 0.13 12.6 0.2 4.6 4 1 1 5 5 4 1 Tetratricopeptide repeat Paf67 PF10255.9 CBZ38679.1 - 0.00066 18.8 2.5 0.58 9.1 0.2 2.6 2 1 0 2 2 2 2 RNA polymerase I-associated factor PAF67 PknG_TPR PF16918.5 CBZ38679.1 - 0.001 17.9 0.4 0.006 15.4 0.0 2.2 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat Fis1_TPR_C PF14853.6 CBZ38679.1 - 0.015 15.4 3.9 12 6.1 0.0 5.4 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 CBZ38679.1 - 0.015 15.7 0.2 0.015 15.7 0.2 3.6 4 1 0 4 4 3 0 Bacterial transcriptional activator domain TPR_4 PF07721.14 CBZ38679.1 - 0.016 15.8 13.8 0.051 14.2 2.1 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 CBZ38679.1 - 0.016 14.2 1.1 0.87 8.5 0.0 2.8 2 1 2 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 CBZ38679.1 - 0.039 12.9 0.2 18 4.1 0.1 3.2 2 1 1 4 4 4 0 NMDA receptor-regulated protein 1 DUF3808 PF10300.9 CBZ38679.1 - 0.055 12.2 0.1 0.081 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Alkyl_sulf_dimr PF14863.6 CBZ38679.1 - 0.072 13.5 0.4 15 6.0 0.0 3.3 2 1 0 3 3 3 0 Alkyl sulfatase dimerisation NatB_MDM20 PF09797.9 CBZ38679.1 - 0.11 11.4 1.0 0.9 8.4 0.2 2.1 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit DUF5113 PF17140.4 CBZ38679.1 - 0.31 10.8 3.8 11 5.8 0.1 3.7 4 0 0 4 4 3 0 Domain of unknown function (DUF5113) DUF3856 PF12968.7 CBZ38679.1 - 0.31 11.1 3.6 7.3 6.7 0.0 3.7 5 0 0 5 5 4 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 CBZ38679.1 - 0.9 9.7 8.6 15 5.7 0.3 5.8 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain ANAPC5 PF12862.7 CBZ38679.1 - 2.1 8.5 6.4 27 4.9 0.2 3.5 3 2 1 4 4 3 0 Anaphase-promoting complex subunit 5 Pkinase PF00069.25 CBZ38680.1 - 4.1e-49 167.3 0.0 1.1e-45 156.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38680.1 - 4.1e-34 118.0 0.0 2.3e-33 115.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ38680.1 - 2.4e-06 27.1 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CBZ38680.1 - 0.00053 18.9 0.0 0.00085 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CBZ38680.1 - 0.24 10.4 0.1 0.37 9.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ribosomal_S18 PF01084.20 CBZ38682.1 - 0.00015 21.9 0.0 0.00032 20.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 Glucokinase PF02685.16 CBZ38683.1 - 4.6e-15 55.4 0.0 1.9e-14 53.4 0.0 1.9 1 1 0 1 1 1 1 Glucokinase Endonuclease_5 PF04493.14 CBZ38684.1 - 4.4e-53 179.9 0.0 5.8e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 CBZ38684.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 UvrC Helix-hairpin-helix N-terminal adh_short PF00106.25 CBZ38685.1 - 6.9e-16 58.3 0.8 5.6e-08 32.5 0.1 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ38685.1 - 7.1e-06 25.7 0.6 0.0032 17.1 0.1 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ38685.1 - 0.00034 20.6 1.5 0.0011 18.9 1.5 1.9 1 1 0 1 1 1 1 KR domain Toxin_TOLIP PF00087.21 CBZ38685.1 - 0.044 14.0 1.1 0.13 12.5 0.8 1.9 2 0 0 2 2 2 0 Snake toxin and toxin-like protein NAD_binding_2 PF03446.15 CBZ38685.1 - 0.062 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Gp_dh_C PF02800.20 CBZ38686.1 - 2.2e-68 228.8 0.0 3e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CBZ38686.1 - 7.7e-41 138.5 0.4 1.8e-40 137.4 0.3 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CBZ38686.1 - 0.0015 18.7 0.8 0.0075 16.4 0.8 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Phage_attach PF05354.11 CBZ38686.1 - 0.041 13.8 0.4 1.8 8.5 0.1 2.3 2 0 0 2 2 2 0 Phage Head-Tail Attachment 2-Hacid_dh_C PF02826.19 CBZ38686.1 - 0.044 13.2 0.0 0.078 12.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aminotran_1_2 PF00155.21 CBZ38687.1 - 6.5e-62 209.8 0.0 7.8e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CBZ38687.1 - 0.0039 16.5 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CBZ38687.1 - 0.011 14.3 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RdRP_5 PF07925.11 CBZ38687.1 - 0.1 10.0 0.0 0.14 9.6 0.0 1.1 1 0 0 1 1 1 0 Reovirus RNA-dependent RNA polymerase lambda 3 Sterol_MT_C PF08498.10 CBZ38689.1 - 6.2e-24 84.1 0.0 1.3e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CBZ38689.1 - 8.7e-17 61.6 0.7 3.3e-16 59.7 0.1 2.3 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ38689.1 - 5.1e-14 52.8 0.2 3.6e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ38689.1 - 2.1e-11 43.8 0.1 3.9e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBZ38689.1 - 2.7e-09 36.7 0.1 4.1e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CBZ38689.1 - 5.1e-08 32.9 0.0 8.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ38689.1 - 1.5e-07 31.0 0.1 3.3e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CBZ38689.1 - 1.5e-06 28.8 0.2 6e-05 23.7 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBZ38689.1 - 0.0067 16.0 0.4 0.011 15.3 0.4 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 CBZ38689.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Sterol_MT_C PF08498.10 CBZ38690.1 - 6.2e-24 84.1 0.0 1.3e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CBZ38690.1 - 8.7e-17 61.6 0.7 3.3e-16 59.7 0.1 2.3 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ38690.1 - 5.1e-14 52.8 0.2 3.6e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ38690.1 - 2.1e-11 43.8 0.1 3.9e-11 43.0 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CBZ38690.1 - 2.7e-09 36.7 0.1 4.1e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CBZ38690.1 - 5.1e-08 32.9 0.0 8.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ38690.1 - 1.5e-07 31.0 0.1 3.3e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CBZ38690.1 - 1.5e-06 28.8 0.2 6e-05 23.7 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_15 PF09445.10 CBZ38690.1 - 0.0067 16.0 0.4 0.011 15.3 0.4 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 CBZ38690.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 EF-hand_7 PF13499.6 CBZ38691.1 - 9.7e-05 22.7 0.0 0.00018 21.9 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CBZ38691.1 - 0.011 15.6 0.0 7.5 6.8 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 CBZ38691.1 - 0.016 14.7 0.0 5.3 6.8 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 CBZ38691.1 - 0.13 12.2 0.0 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair Cullin_Nedd8 PF10557.9 CBZ38692.1 - 2.4e-17 62.7 0.1 4.7e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Cullin protein neddylation domain TilS PF09179.11 CBZ38692.1 - 1.9 9.0 10.5 4.9 7.7 2.4 4.1 3 0 0 3 3 3 0 TilS substrate binding domain Peptidase_S9 PF00326.21 CBZ38693.1 - 3.8e-32 111.5 0.1 7.5e-32 110.5 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.21 CBZ38693.1 - 5.4e-25 87.9 0.0 9.6e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_6 PF12697.7 CBZ38693.1 - 0.0062 17.2 1.5 0.01 16.4 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 CBZ38693.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 CBZ38693.1 - 0.032 13.8 0.0 0.12 11.9 0.0 1.9 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) FYVE PF01363.21 CBZ38695.1 - 2.5e-09 37.1 8.2 4.6e-09 36.3 8.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 CBZ38695.1 - 0.052 13.8 8.4 0.13 12.4 8.4 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 CBZ38695.1 - 0.5 10.6 9.9 4.7 7.5 7.2 2.7 2 1 0 2 2 2 0 B-box zinc finger PEHE PF15275.6 CBZ38695.1 - 4.1 8.0 6.9 23 5.6 6.9 2.0 1 1 0 1 1 1 0 PEHE domain zf-C2H2_6 PF13912.6 CBZ38695.1 - 7.4 6.7 10.7 7.9 6.6 1.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger His_Phos_2 PF00328.22 CBZ38698.1 - 2.3e-11 43.7 1.5 2.1e-07 30.6 0.2 3.1 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.22 CBZ38699.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Condensation PF00668.20 CBZ38699.1 - 0.11 11.1 0.8 0.14 10.8 0.8 1.1 1 0 0 1 1 1 0 Condensation domain CAP_N PF01213.19 CBZ38699.1 - 4.1 6.8 12.0 2.8 7.3 10.5 1.4 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Plasmodium_Vir PF05795.11 CBZ38700.1 - 0.064 12.7 1.7 0.11 11.9 1.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein WD40 PF00400.32 CBZ38701.1 - 5.4e-18 65.0 14.5 1.8e-06 28.5 0.8 6.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ38701.1 - 2e-08 34.4 0.5 13 6.2 0.0 5.4 5 0 0 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nic96 PF04097.14 CBZ38702.1 - 1e-55 189.4 0.1 2e-55 188.5 0.1 1.3 1 1 0 1 1 1 1 Nup93/Nic96 SNAPc_SNAP43 PF09808.9 CBZ38703.1 - 0.00063 19.7 0.0 0.00094 19.2 0.0 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 DEAD PF00270.29 CBZ38704.1 - 5.8e-26 91.3 0.0 9.5e-25 87.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ38704.1 - 1.5e-24 86.5 0.0 3.5e-22 78.9 0.0 2.3 2 0 0 2 2 2 2 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 CBZ38704.1 - 0.0031 17.7 0.0 0.051 13.7 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 CBZ38704.1 - 0.014 15.4 0.0 0.63 10.0 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit UTP25 PF06862.12 CBZ38704.1 - 0.016 14.0 0.0 0.73 8.5 0.0 2.7 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CBZ38704.1 - 0.06 13.6 0.1 6.7 7.0 0.0 2.7 1 1 0 2 2 2 0 AAA domain K_channel_TID PF07941.11 CBZ38704.1 - 0.086 13.3 0.8 0.19 12.2 0.8 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain FA_hydroxylase PF04116.13 CBZ38705.1 - 2.1e-21 76.6 14.7 2.1e-21 76.6 14.7 2.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily HEAT PF02985.22 CBZ38707.1 - 0.0032 17.6 7.3 1.5 9.3 0.1 5.0 4 0 0 4 4 4 2 HEAT repeat His_Phos_2 PF00328.22 CBZ38708.1 - 1.8e-09 37.5 1.2 0.011 15.1 0.0 3.1 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) GDPD PF03009.17 CBZ38709.1 - 9.8e-38 130.4 0.0 1.4e-37 129.9 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family His_Phos_2 PF00328.22 CBZ38710.1 - 5.3e-08 32.6 0.3 1.1e-05 24.9 0.0 3.0 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) RCC1 PF00415.18 CBZ38711.1 - 5.6e-23 81.3 11.5 3e-06 27.8 0.0 6.3 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ38711.1 - 1.9e-22 78.5 14.4 6.3e-09 35.4 0.2 3.9 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 CBZ38711.1 - 0.0051 17.0 1.1 2.8 8.2 0.0 3.1 2 1 0 2 2 2 2 Putative heavy-metal chelation Mur_ligase_M PF08245.12 CBZ38712.1 - 5.3e-10 39.6 0.3 1.6e-09 38.0 0.3 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CBZ38712.1 - 0.087 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain CAP_N PF01213.19 CBZ38712.1 - 2.4 7.5 5.3 4.2 6.8 5.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CBZ38712.1 - 4.3 7.4 6.0 10 6.2 6.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Androgen_recep PF02166.16 CBZ38712.1 - 7.3 5.3 6.6 20 3.8 6.2 1.8 2 0 0 2 2 2 0 Androgen receptor VRR_NUC PF08774.11 CBZ38713.1 - 2.7e-06 27.4 0.0 6.2e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain TPR_12 PF13424.6 CBZ38713.1 - 0.059 13.7 2.7 0.17 12.2 0.8 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CBZ38713.1 - 3 7.9 6.9 1.4 8.9 1.9 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 CBZ38714.1 - 3.4e-23 82.4 0.0 1.8e-11 43.9 0.0 3.4 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38714.1 - 2.9e-11 43.2 0.0 1.1e-09 38.0 0.0 2.7 3 0 0 3 3 3 1 Protein tyrosine kinase PCI PF01399.27 CBZ38715.1 - 0.002 18.6 0.0 0.34 11.4 0.0 3.0 3 0 0 3 3 3 2 PCI domain Methyltransf_11 PF08241.12 CBZ38716.1 - 5.9e-11 42.9 0.1 3.5e-07 30.8 0.0 3.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ38716.1 - 1.5e-10 41.6 0.1 3.6e-05 24.4 0.0 3.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ38716.1 - 5.3e-06 26.4 0.0 8.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ38716.1 - 0.00013 22.7 0.0 0.0019 18.9 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ38716.1 - 0.0024 17.7 0.0 8.1 6.2 0.0 3.0 3 0 0 3 3 3 2 Methyltransferase domain 2-oxoacid_dh PF00198.23 CBZ38717.1 - 1.8e-76 256.7 0.0 2.3e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 CBZ38717.1 - 4.9e-12 46.0 2.2 1.4e-11 44.5 0.4 2.6 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl PF00364.22 CBZ38717.1 - 3.2e-10 39.7 0.0 1.3e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 Biotin-requiring enzyme DUF3597 PF12200.8 CBZ38717.1 - 4.4 7.8 9.3 6.8 7.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Metallophos_2 PF12850.7 CBZ38718.1 - 3e-07 30.8 1.2 1.2e-05 25.5 1.2 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CBZ38718.1 - 0.00051 20.6 0.1 0.0013 19.3 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MMS22L_C PF14911.6 CBZ38719.1 - 0.11 11.5 0.0 0.27 10.3 0.0 1.6 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal Pentapeptide_4 PF13599.6 CBZ38720.1 - 4.2e-16 58.9 22.0 5e-09 36.2 8.8 3.0 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 CBZ38720.1 - 2.8e-11 43.4 11.2 3.1e-05 24.0 0.2 4.1 2 2 2 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 CBZ38720.1 - 5.4e-09 35.5 27.4 2.2e-05 24.0 2.1 4.6 2 1 3 5 5 5 4 Pentapeptide repeats (8 copies) IPPT PF01715.17 CBZ38722.1 - 0.3 10.8 3.2 1.1 9.1 2.9 2.1 1 1 0 1 1 1 0 IPP transferase Peptidase_M41 PF01434.18 CBZ38723.1 - 3.2e-55 186.9 0.1 5e-55 186.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CBZ38723.1 - 2.4e-41 141.2 0.0 4.8e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ38723.1 - 1.2e-06 28.2 0.4 4.1e-06 26.5 0.2 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 CBZ38723.1 - 1.1e-05 25.4 0.0 3.9e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ38723.1 - 1.9e-05 25.1 0.1 0.00015 22.2 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CBZ38723.1 - 3.8e-05 24.0 0.3 0.011 16.0 0.1 2.9 2 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 CBZ38723.1 - 0.00012 21.9 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CBZ38723.1 - 0.00021 20.9 0.6 0.064 12.8 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 CBZ38723.1 - 0.00042 20.3 0.0 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CBZ38723.1 - 0.001 18.4 0.0 0.0028 16.9 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_18 PF13238.6 CBZ38723.1 - 0.0012 19.4 0.0 0.0032 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CBZ38723.1 - 0.0026 17.7 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain IstB_IS21 PF01695.17 CBZ38723.1 - 0.0026 17.5 0.0 0.0074 16.0 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein NACHT PF05729.12 CBZ38723.1 - 0.0026 17.7 0.2 0.016 15.1 0.1 2.1 1 1 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 CBZ38723.1 - 0.0042 17.5 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CBZ38723.1 - 0.0055 16.1 0.2 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CBZ38723.1 - 0.015 15.6 0.0 0.044 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 CBZ38723.1 - 0.02 15.2 0.0 0.12 12.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_2 PF07724.14 CBZ38723.1 - 0.022 14.9 0.0 0.079 13.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 CBZ38723.1 - 0.023 14.7 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CBZ38723.1 - 0.032 14.4 0.0 0.064 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBZ38723.1 - 0.065 12.5 0.1 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 CBZ38723.1 - 0.075 13.6 0.6 0.33 11.5 0.3 2.2 2 0 0 2 2 2 0 ABC transporter ATPase PF06745.13 CBZ38723.1 - 0.096 12.0 0.1 0.8 9.0 0.0 2.4 3 0 0 3 3 3 0 KaiC TniB PF05621.11 CBZ38723.1 - 0.15 11.4 0.0 4.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 CBZ38723.1 - 0.15 11.2 0.0 0.37 9.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 CBZ38723.1 - 0.24 10.4 0.0 0.44 9.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Peptidase_M50B PF13398.6 CBZ38723.1 - 0.33 10.5 0.8 0.48 10.0 0.0 1.5 2 0 0 2 2 1 0 Peptidase M50B-like RIX1 PF08167.12 CBZ38724.1 - 3.1e-07 30.3 2.0 1.1e-06 28.6 2.0 2.0 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis IBN_N PF03810.19 CBZ38724.1 - 0.00056 19.8 2.3 0.089 12.7 0.1 4.3 3 1 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.6 CBZ38724.1 - 0.00059 20.3 3.7 0.17 12.4 0.0 4.3 3 2 1 4 4 4 2 HEAT-like repeat B56 PF01603.20 CBZ38724.1 - 0.028 13.4 0.0 0.091 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) TetR_C_15 PF17918.1 CBZ38724.1 - 0.052 14.3 0.1 3 8.6 0.0 3.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HEAT PF02985.22 CBZ38724.1 - 0.4 11.1 2.1 18 6.0 0.0 4.9 6 0 0 6 6 6 0 HEAT repeat Tyr_Deacylase PF02580.16 CBZ38725.1 - 2.2e-46 158.0 0.0 2.4e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Sec23_helical PF04815.15 CBZ38726.1 - 0.012 15.4 0.2 0.089 12.6 0.0 2.5 2 0 0 2 2 2 0 Sec23/Sec24 helical domain Acetyltransf_1 PF00583.25 CBZ38727.1 - 8.4e-16 58.3 0.1 1.1e-15 57.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CBZ38727.1 - 1.1e-06 29.0 0.0 1.7e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CBZ38727.1 - 0.00014 21.8 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CBZ38727.1 - 0.00096 19.2 0.0 0.0017 18.4 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 CBZ38727.1 - 0.003 17.5 0.0 0.0081 16.1 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_6 PF13480.7 CBZ38727.1 - 0.0073 16.5 0.5 0.016 15.4 0.5 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3161 PF11362.8 CBZ38727.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3161) Acetyltransf_16 PF05301.11 CBZ38727.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 MFS_1 PF07690.16 CBZ38728.1 - 7.1e-14 51.5 42.9 6.1e-13 48.4 27.3 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 CBZ38728.1 - 1.6e-13 50.7 11.1 1.6e-13 50.7 11.1 2.1 3 0 0 3 3 3 1 Nodulin-like TP6A_N PF04406.14 CBZ38730.1 - 9.2e-05 22.4 0.0 0.00055 19.9 0.0 2.1 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 CBZ38730.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2399) NDK PF00334.19 CBZ38731.1 - 0.0009 19.3 0.0 0.078 13.0 0.0 3.3 4 0 0 4 4 4 1 Nucleoside diphosphate kinase RGS PF00615.19 CBZ38735.1 - 0.047 14.0 0.7 0.42 10.9 0.1 2.2 2 0 0 2 2 2 0 Regulator of G protein signaling domain HA2 PF04408.23 CBZ38736.1 - 4.3e-18 65.6 0.2 2e-17 63.4 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBZ38736.1 - 4.5e-17 62.2 0.0 2.7e-16 59.7 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBZ38736.1 - 1.7e-14 54.1 0.0 7.2e-14 52.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ38736.1 - 1.2e-08 34.9 0.6 8.4e-08 32.2 0.1 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ38736.1 - 5.9e-06 26.6 0.8 2.1e-05 24.8 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CBZ38736.1 - 6.9e-05 22.6 0.4 0.00019 21.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CBZ38736.1 - 0.022 14.5 0.1 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 CBZ38736.1 - 0.037 14.5 1.5 0.13 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ38736.1 - 0.05 13.9 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 CBZ38736.1 - 0.052 13.5 0.7 3 7.8 0.0 3.1 3 0 0 3 3 3 0 Microtubule binding ABC_tran PF00005.27 CBZ38736.1 - 0.067 13.7 0.1 0.8 10.2 0.1 2.7 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CBZ38736.1 - 0.091 12.3 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CBZ38736.1 - 0.095 12.9 2.4 0.9 9.7 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CBZ38736.1 - 3.1 7.5 6.0 34 4.1 0.0 3.0 3 0 0 3 3 3 0 AAA domain RasGAP_C PF03836.15 CBZ38738.1 - 0.0028 17.8 0.7 0.0032 17.6 0.7 1.1 1 0 0 1 1 1 1 RasGAP C-terminus APG6_N PF17675.1 CBZ38738.1 - 0.0066 17.0 7.5 0.0085 16.6 7.5 1.1 1 0 0 1 1 1 1 Apg6 coiled-coil region Spc7 PF08317.11 CBZ38738.1 - 0.011 14.6 4.3 0.012 14.5 4.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 CBZ38738.1 - 0.014 15.5 3.2 0.015 15.5 3.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF2968 PF11180.8 CBZ38738.1 - 0.034 13.8 5.8 0.035 13.7 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) CENP-Q PF13094.6 CBZ38738.1 - 0.034 14.3 4.1 0.039 14.2 4.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit GvpG PF05120.12 CBZ38738.1 - 0.039 14.0 6.4 0.06 13.4 6.4 1.4 1 1 0 1 1 1 0 Gas vesicle protein G OmpH PF03938.14 CBZ38738.1 - 0.039 14.3 6.5 0.041 14.2 6.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TACC_C PF05010.14 CBZ38738.1 - 0.041 13.7 4.6 0.052 13.3 4.6 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Baculo_PEP_C PF04513.12 CBZ38738.1 - 0.043 13.8 0.8 0.049 13.7 0.8 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Occludin_ELL PF07303.13 CBZ38738.1 - 0.045 14.5 0.8 0.065 14.0 0.8 1.3 1 1 0 1 1 1 0 Occludin homology domain Spc24 PF08286.11 CBZ38738.1 - 0.048 13.9 1.9 0.058 13.6 1.9 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 CBZ38738.1 - 0.076 12.4 4.6 0.08 12.3 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS6_N PF14661.6 CBZ38738.1 - 0.086 12.4 2.7 0.1 12.2 2.7 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus FapA PF03961.13 CBZ38738.1 - 0.095 11.3 0.8 0.1 11.2 0.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A FliD_N PF02465.18 CBZ38738.1 - 0.099 13.3 1.6 0.13 13.0 1.6 1.1 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus V_ATPase_I PF01496.19 CBZ38738.1 - 0.1 10.5 1.1 0.11 10.4 1.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RmuC PF02646.16 CBZ38738.1 - 0.11 11.6 3.1 0.13 11.4 3.1 1.1 1 0 0 1 1 1 0 RmuC family Phage_GP20 PF06810.11 CBZ38738.1 - 0.11 12.2 5.3 0.13 12.1 2.4 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 Borrelia_P83 PF05262.11 CBZ38738.1 - 0.12 10.8 3.2 0.12 10.8 3.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Herpes_UL25 PF01499.16 CBZ38738.1 - 0.28 9.7 2.0 0.32 9.5 2.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL25 family FUSC PF04632.12 CBZ38738.1 - 0.47 8.9 3.5 0.49 8.9 3.5 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIC PF04977.15 CBZ38738.1 - 0.83 9.5 10.4 1.8 8.4 0.8 2.2 1 1 1 2 2 2 0 Septum formation initiator SlyX PF04102.12 CBZ38738.1 - 1 10.0 7.8 8 7.2 7.8 2.0 1 1 0 1 1 1 0 SlyX GIT_CC PF16559.5 CBZ38738.1 - 1.6 8.6 6.1 4.5 7.2 1.9 2.1 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4140 PF13600.6 CBZ38738.1 - 1.7 9.1 6.2 3.2 8.2 6.2 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Lactamase_B_2 PF12706.7 CBZ38739.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_S24e PF01282.19 CBZ38740.1 - 6e-27 93.4 0.0 1.1e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e ASH PF15780.5 CBZ38741.1 - 1e-21 76.9 2.5 0.00051 20.2 0.0 9.6 11 0 0 11 11 11 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 CBZ38741.1 - 9.9e-12 44.7 0.0 0.067 13.0 0.0 6.4 6 0 0 6 6 6 3 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CBZ38741.1 - 8.8e-05 22.7 0.0 6.6 7.1 0.0 4.5 4 0 0 4 4 4 2 Transmembrane protein 131-like DUF1573 PF07610.11 CBZ38741.1 - 0.17 11.9 0.0 17 5.5 0.0 4.3 6 0 0 6 6 6 0 Protein of unknown function (DUF1573) ABC2_membrane PF01061.24 CBZ38742.1 - 4.9e-34 117.6 17.1 4.9e-34 117.6 17.1 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CBZ38742.1 - 9.3e-23 81.3 0.0 1.5e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CBZ38742.1 - 3.3e-07 30.4 0.3 0.0097 15.7 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CBZ38742.1 - 0.00062 20.2 1.1 0.0069 16.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CBZ38742.1 - 0.0015 18.5 0.1 0.0031 17.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CBZ38742.1 - 0.0045 16.7 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CBZ38742.1 - 0.0076 16.5 0.1 0.036 14.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CBZ38742.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 CBZ38742.1 - 0.017 14.8 1.8 0.082 12.6 0.2 2.5 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CBZ38742.1 - 0.04 14.1 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CBZ38742.1 - 0.041 14.4 0.0 0.085 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 CBZ38742.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 CBZ38742.1 - 0.063 12.3 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 CBZ38742.1 - 0.1 12.4 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 CBZ38742.1 - 0.22 12.0 0.0 0.38 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 CBZ38743.1 - 1.1e-05 24.6 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain AAA_16 PF13191.6 CBZ38743.1 - 0.0066 16.8 1.4 0.028 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CBZ38743.1 - 0.23 11.9 0.1 0.45 11.0 0.1 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PHF5 PF03660.14 CBZ38745.1 - 4.6e-34 116.8 9.3 5.2e-34 116.6 9.3 1.0 1 0 0 1 1 1 1 PHF5-like protein FYVE_2 PF02318.16 CBZ38745.1 - 0.44 10.8 8.9 0.2 11.9 6.9 1.5 2 0 0 2 2 2 0 FYVE-type zinc finger TF_Zn_Ribbon PF08271.12 CBZ38745.1 - 1.1 8.8 9.3 0.77 9.3 0.7 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding zf-CHY PF05495.12 CBZ38745.1 - 2.9 8.4 10.4 12 6.5 10.4 2.0 1 1 0 1 1 1 0 CHY zinc finger DZR PF12773.7 CBZ38745.1 - 3.1 7.9 10.9 11 6.2 2.6 2.6 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.6 CBZ38745.1 - 5.1 7.0 14.3 0.13 12.1 4.5 2.8 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_2 PF03107.16 CBZ38745.1 - 6.3 7.2 13.9 14 6.1 7.1 3.1 1 1 1 2 2 2 0 C1 domain RecR PF02132.15 CBZ38745.1 - 8.4 6.1 15.7 2.8 7.6 6.7 3.1 2 1 1 3 3 3 0 RecR protein zf-RING_2 PF13639.6 CBZ38746.1 - 4.2e-12 46.2 6.2 4.2e-12 46.2 6.2 2.3 3 0 0 3 3 2 1 Ring finger domain zf-RING_11 PF17123.5 CBZ38746.1 - 9.5e-10 38.0 3.6 9.5e-10 38.0 3.6 1.8 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CBZ38746.1 - 3.3e-08 33.2 5.7 8.3e-08 31.9 5.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CBZ38746.1 - 6.2e-07 29.2 3.6 6.2e-07 29.2 3.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CBZ38746.1 - 2.4e-06 27.7 7.1 1.4e-05 25.3 7.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CBZ38746.1 - 4.8e-06 26.5 3.5 1.1e-05 25.3 3.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CBZ38746.1 - 1.4e-05 25.0 4.5 3.4e-05 23.7 4.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CBZ38746.1 - 2.2e-05 24.2 4.2 2.2e-05 24.2 4.2 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CBZ38746.1 - 0.00078 19.0 4.7 0.00078 19.0 4.7 2.0 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 CBZ38746.1 - 0.015 15.2 5.0 0.015 15.2 5.0 2.3 2 0 0 2 2 2 0 PHD-finger zf-ANAPC11 PF12861.7 CBZ38746.1 - 0.073 13.1 4.7 0.25 11.4 4.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_9 PF13901.6 CBZ38746.1 - 0.087 12.8 3.7 0.77 9.7 2.3 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon FANCL_C PF11793.8 CBZ38746.1 - 0.3 11.3 4.7 1.1 9.5 4.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CBZ38746.1 - 0.44 10.4 5.0 1.3 8.9 5.0 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 CBZ38746.1 - 2 8.6 5.0 0.73 10.0 1.8 1.9 2 0 0 2 2 1 0 Zinc ribbon domain Prok-RING_1 PF14446.6 CBZ38746.1 - 3.1 7.8 7.9 2 8.4 3.6 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PI3_PI4_kinase PF00454.27 CBZ38747.1 - 6e-27 95.0 0.0 1.1e-26 94.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 CBZ38747.1 - 5.7e-06 25.5 0.0 0.078 11.9 0.0 2.5 2 0 0 2 2 2 2 NUC194 domain FATC PF02260.20 CBZ38747.1 - 0.00015 21.5 0.0 0.00049 19.9 0.0 1.9 1 0 0 1 1 1 1 FATC domain MSL1_dimer PF16801.5 CBZ38747.1 - 2.9 7.7 7.6 0.23 11.3 0.8 2.5 2 0 0 2 2 2 0 Dimerisation domain of Male-specific-Lethal 1 ATP-grasp_2 PF08442.10 CBZ38748.1 - 9.6e-65 217.9 4.4 1.5e-64 217.3 4.4 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CBZ38748.1 - 1.2e-21 77.1 1.2 1.2e-21 77.1 1.2 2.4 3 0 0 3 3 3 1 CoA-ligase KleE PF17394.2 CBZ38749.1 - 0.13 12.5 0.2 0.17 12.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein YlaH PF14036.6 CBZ38750.1 - 0.056 13.8 3.1 0.061 13.7 1.4 1.8 2 0 0 2 2 2 0 YlaH-like protein DUF1430 PF07242.11 CBZ38750.1 - 0.1 12.9 1.0 0.21 11.9 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1430) Bromodomain PF00439.25 CBZ38751.1 - 5.7e-22 77.6 0.0 8.9e-22 77.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain ANAPC15 PF15243.6 CBZ38751.1 - 1 9.8 0.0 0.47 10.9 3.4 3.7 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 15 TFIIA PF03153.13 CBZ38751.1 - 9.6 6.1 17.2 11 5.9 17.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTP1_OBG PF01018.22 CBZ38752.1 - 1.6e-39 135.0 5.8 2.3e-39 134.5 5.8 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 CBZ38752.1 - 4e-18 65.6 0.0 7.1e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ38752.1 - 2.9e-06 26.9 0.0 7.8e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DSHCT PF08148.12 CBZ38753.1 - 3.6e-46 156.8 1.0 9.1e-46 155.5 0.4 2.1 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 CBZ38753.1 - 6.2e-44 151.0 0.7 1.2e-43 150.1 0.3 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 CBZ38753.1 - 2e-22 79.8 0.3 3.1e-21 75.9 0.0 2.9 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ38753.1 - 3e-07 30.7 0.0 1.9e-06 28.1 0.0 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ38753.1 - 2.1e-06 27.8 0.0 5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 CBZ38753.1 - 0.0068 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein T2SSE PF00437.20 CBZ38753.1 - 0.0084 15.2 0.1 0.054 12.6 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein FlxA PF14282.6 CBZ38753.1 - 0.011 15.7 2.8 0.023 14.7 2.8 1.4 1 0 0 1 1 1 0 FlxA-like protein ATPase_2 PF01637.18 CBZ38753.1 - 0.023 14.6 0.8 0.073 13.0 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CBZ38753.1 - 0.029 14.6 0.0 0.15 12.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain MutS_III PF05192.18 CBZ38753.1 - 0.063 13.5 1.5 1.8 8.7 0.0 2.8 1 1 0 2 2 2 0 MutS domain III Zot PF05707.12 CBZ38753.1 - 0.099 12.3 0.0 0.57 9.8 0.0 2.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DnaB_C PF03796.15 CBZ38753.1 - 0.22 10.8 1.7 1.2 8.4 0.1 2.7 3 1 1 4 4 4 0 DnaB-like helicase C terminal domain GSHPx PF00255.19 CBZ38754.1 - 2.7e-27 94.5 0.1 3.3e-27 94.2 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.10 CBZ38754.1 - 0.006 16.3 0.0 0.0081 15.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin DUF2095 PF09868.9 CBZ38754.1 - 0.2 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) RNase_PH PF01138.21 CBZ38755.1 - 8.8e-29 100.7 0.3 1.2e-28 100.2 0.3 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CBZ38755.1 - 5.9e-05 23.0 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1623 PF07785.11 CBZ38755.1 - 0.046 13.9 0.7 0.084 13.1 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1623) Adap_comp_sub PF00928.21 CBZ38756.1 - 1.2e-56 192.0 0.0 1.5e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CBZ38756.1 - 0.00023 21.1 0.5 0.00037 20.4 0.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CBZ38756.1 - 0.0084 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain RRM_1 PF00076.22 CBZ38757.1 - 2.4e-08 33.7 0.0 3.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ38757.1 - 1.1e-07 31.5 0.0 1.4e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_Gp23 PF10669.9 CBZ38757.1 - 0.017 15.4 2.3 0.027 14.8 2.3 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Cullin PF00888.22 CBZ38759.1 - 3.1e-61 207.8 0.0 3.6e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CBZ38759.1 - 4.7e-12 45.8 0.1 1e-10 41.5 0.0 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain Fibrillarin PF01269.17 CBZ38760.1 - 3.2e-101 337.2 0.0 3.6e-101 337.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CBZ38760.1 - 0.00046 19.9 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 CBZ38760.1 - 0.023 14.5 0.1 0.041 13.6 0.1 1.3 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BPL_LplA_LipB PF03099.19 CBZ38761.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.6 1 1 0 1 1 1 0 Biotin/lipoate A/B protein ligase family vATP-synt_E PF01991.18 CBZ38763.1 - 2.1e-40 138.2 8.4 2.4e-40 138.1 8.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Acyl-CoA_dh_N PF02771.16 CBZ38763.1 - 0.11 13.1 3.3 0.12 13.0 1.7 1.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain YjeJ PF15922.5 CBZ38763.1 - 0.13 11.4 5.1 0.21 10.8 5.0 1.4 1 1 0 1 1 1 0 YjeJ-like Pannexin_like PF12534.8 CBZ38763.1 - 1.2 8.1 6.6 1.7 7.7 6.6 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 DUF1266 PF06889.11 CBZ38764.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) EF-hand_8 PF13833.6 CBZ38765.1 - 1.5e-06 27.9 0.3 9.1e-05 22.2 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 CBZ38765.1 - 0.0001 22.7 0.4 0.012 16.1 0.0 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CBZ38765.1 - 0.014 14.9 0.1 3.2 7.5 0.0 3.4 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.6 CBZ38765.1 - 0.046 13.7 0.1 19 5.5 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain Pro_isomerase PF00160.21 CBZ38766.1 - 9.2e-38 130.0 0.0 1.1e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ArfGap PF01412.18 CBZ38768.1 - 5e-23 81.4 0.1 1.1e-22 80.3 0.0 1.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf REV1_C PF16727.5 CBZ38768.1 - 0.021 15.2 0.1 0.038 14.4 0.1 1.3 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain IRF-2BP1_2 PF11261.8 CBZ38768.1 - 0.1 12.2 0.3 0.28 10.8 0.3 1.6 1 0 0 1 1 1 0 Interferon regulatory factor 2-binding protein zinc finger TBCC PF07986.12 CBZ38769.1 - 7.6e-25 87.0 0.6 1.6e-24 86.0 0.6 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 CBZ38769.1 - 0.00027 21.4 7.8 0.00052 20.4 7.8 1.4 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain TAN PF11640.8 CBZ38769.1 - 0.047 13.8 0.5 0.079 13.1 0.5 1.3 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair cobW PF02492.19 CBZ38770.1 - 7.5e-48 162.4 0.3 1e-47 162.0 0.3 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CBZ38770.1 - 0.00082 19.3 0.2 0.89 9.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 CBZ38770.1 - 0.0044 17.6 0.1 0.28 11.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CBZ38770.1 - 0.01 15.5 0.1 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.14 CBZ38770.1 - 0.027 14.3 0.2 0.23 11.4 0.2 2.2 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.14 CBZ38770.1 - 0.035 14.0 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain AAA_33 PF13671.6 CBZ38770.1 - 0.066 13.4 0.1 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CBZ38770.1 - 0.069 13.4 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CBZ38770.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 CBZ38770.1 - 0.14 11.9 0.4 0.31 10.8 0.4 1.6 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 CBZ38770.1 - 0.14 11.8 0.1 0.55 9.9 0.0 1.9 3 0 0 3 3 3 0 AAA domain Guanylate_cyc PF00211.20 CBZ38771.1 - 1.6e-37 128.9 0.0 2.7e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF1935 PF09149.10 CBZ38771.1 - 8.9e-30 103.1 0.0 1.9e-29 102.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1935) DAG1 PF05454.11 CBZ38771.1 - 0.044 13.2 0.1 0.094 12.1 0.1 1.4 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) zf-CCHC PF00098.23 CBZ38772.1 - 2.4e-16 59.0 85.4 0.00062 19.7 2.4 9.9 10 0 0 10 10 10 8 Zinc knuckle zf-CCHC_2 PF13696.6 CBZ38772.1 - 4.9e-06 26.2 15.2 0.0004 20.1 2.6 9.4 8 1 1 9 9 9 4 Zinc knuckle NYN PF01936.18 CBZ38772.1 - 0.12 12.8 0.0 0.33 11.4 0.0 1.7 2 0 0 2 2 2 0 NYN domain zf-CCHC_4 PF14392.6 CBZ38772.1 - 7.4 6.4 83.8 0.03 14.1 2.8 10.0 6 3 4 10 10 10 0 Zinc knuckle Topoisom_bac PF01131.20 CBZ38773.1 - 1.1e-103 347.5 0.0 2.1e-103 346.5 0.0 1.4 2 0 0 2 2 2 1 DNA topoisomerase Toprim PF01751.22 CBZ38773.1 - 1.4e-16 60.6 0.0 4.5e-16 58.9 0.0 1.9 2 0 0 2 2 2 1 Toprim domain zf-GRF PF06839.12 CBZ38773.1 - 2.2e-07 30.8 1.8 2.2e-07 30.8 1.8 2.6 2 0 0 2 2 2 1 GRF zinc finger zf-C4_Topoisom PF01396.19 CBZ38773.1 - 1e-06 28.4 0.1 1e-06 28.4 0.1 4.8 5 1 0 5 5 5 1 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_12 PF11331.8 CBZ38773.1 - 0.0034 17.2 3.9 0.41 10.5 0.0 4.4 4 0 0 4 4 4 1 Probable zinc-ribbon domain Cys_rich_CPCC PF14206.6 CBZ38773.1 - 0.028 14.2 1.6 0.072 12.9 0.4 2.3 3 0 0 3 3 3 0 Cysteine-rich CPCC HypA PF01155.19 CBZ38773.1 - 0.36 10.9 12.6 0.28 11.2 0.3 4.0 3 1 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_4 PF13717.6 CBZ38773.1 - 0.74 9.8 0.0 0.74 9.8 0.0 4.3 6 0 0 6 6 6 0 zinc-ribbon domain 14-3-3 PF00244.20 CBZ38774.1 - 6.7e-85 284.1 1.0 7.7e-85 283.9 1.0 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 CBZ38774.1 - 0.28 11.5 3.7 0.32 11.3 0.8 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Acetyltransf_17 PF17668.1 CBZ38775.1 - 0.045 14.6 1.2 0.045 14.6 1.2 3.7 4 1 0 4 4 4 0 Acetyltransferase (GNAT) domain Matrilin_ccoil PF10393.9 CBZ38775.1 - 3.6 7.5 15.8 0.31 10.9 0.4 4.0 4 0 0 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin GMC_oxred_N PF00732.19 CBZ38776.1 - 3.4e-48 164.5 0.0 6.8e-48 163.5 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CBZ38776.1 - 1.3e-20 74.4 0.0 2.2e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CBZ38776.1 - 1.6e-07 30.8 4.8 0.00017 20.8 0.8 2.9 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 CBZ38776.1 - 3.7e-05 23.1 0.1 0.0011 18.2 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CBZ38776.1 - 3.7e-05 23.5 9.5 0.0019 17.8 5.0 3.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ38776.1 - 0.0022 18.2 1.0 0.0078 16.4 1.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CBZ38776.1 - 0.0072 15.5 0.7 0.2 10.7 1.5 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CBZ38776.1 - 0.011 14.8 0.6 0.011 14.8 0.6 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 CBZ38776.1 - 0.014 14.7 1.8 0.3 10.4 1.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CBZ38776.1 - 0.014 14.1 0.6 0.043 12.5 0.7 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 CBZ38776.1 - 0.032 13.5 0.2 0.068 12.4 0.2 1.5 1 0 0 1 1 1 0 Thi4 family Flavi_M PF01004.19 CBZ38777.1 - 0.046 13.5 0.2 0.094 12.5 0.2 1.4 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M dCache_1 PF02743.18 CBZ38778.1 - 5e-07 29.8 0.3 0.002 18.0 0.1 2.3 2 0 0 2 2 2 2 Cache domain DUF1712 PF08217.11 CBZ38779.1 - 0.00012 20.7 0.0 0.00017 20.3 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Ribosomal_L20 PF00453.18 CBZ38780.1 - 0.016 15.3 1.0 0.024 14.7 1.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 Ribosomal_L22e PF01776.17 CBZ38781.1 - 3.4e-36 124.0 2.9 4.2e-36 123.6 2.9 1.1 1 0 0 1 1 1 1 Ribosomal L22e protein family ECH_2 PF16113.5 CBZ38782.1 - 1.1e-21 77.7 0.0 3e-11 43.4 0.0 4.0 3 1 0 3 3 3 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CBZ38782.1 - 4.3e-13 49.2 0.0 2.8e-08 33.4 0.0 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase EPO_TPO PF00758.18 CBZ38782.1 - 0.047 13.7 0.0 3 7.8 0.0 2.3 1 1 1 2 2 2 0 Erythropoietin/thrombopoietin Macro PF01661.21 CBZ38783.1 - 0.00029 20.9 0.0 0.00044 20.3 0.0 1.3 1 0 0 1 1 1 1 Macro domain Actin PF00022.19 CBZ38785.1 - 1.1e-98 330.5 0.0 9.5e-98 327.5 0.0 1.9 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CBZ38785.1 - 0.029 14.8 0.0 0.2 12.1 0.0 2.1 2 1 0 2 2 2 0 Cell division protein FtsA Piezo_RRas_bdg PF12166.8 CBZ38788.1 - 2.2e-91 307.3 0.0 3.2e-91 306.7 0.0 1.3 1 0 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain Bromodomain PF00439.25 CBZ38790.1 - 2.4e-13 49.9 0.0 5.2e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain YtzH PF14165.6 CBZ38790.1 - 0.099 13.0 0.7 0.28 11.6 0.1 2.0 2 1 0 2 2 2 0 YtzH-like protein BET PF17035.5 CBZ38790.1 - 0.14 12.4 0.3 0.29 11.4 0.3 1.6 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation Ribosomal_L29e PF01779.17 CBZ38793.1 - 2.2e-12 47.1 6.0 2.2e-12 47.1 6.0 1.9 2 0 0 2 2 2 1 Ribosomal L29e protein family Ribosomal_L29e PF01779.17 CBZ38794.1 - 2.2e-12 47.1 6.0 2.2e-12 47.1 6.0 1.9 2 0 0 2 2 2 1 Ribosomal L29e protein family adh_short PF00106.25 CBZ38795.1 - 8e-37 126.6 0.0 1.1e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CBZ38795.1 - 2.7e-15 56.5 0.0 4.1e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CBZ38795.1 - 6.3e-10 39.3 1.0 2.8e-09 37.1 1.0 1.9 1 1 0 1 1 1 1 KR domain Methyltransf_31 PF13847.6 CBZ38795.1 - 0.001 18.9 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CBZ38795.1 - 0.023 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.15 CBZ38795.1 - 0.032 13.4 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CBZ38795.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Vps26 PF03643.15 CBZ38796.1 - 6.2e-53 179.6 0.6 7.6e-53 179.3 0.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CBZ38796.1 - 0.00024 21.2 1.7 0.41 10.7 0.0 3.1 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain CRAL_TRIO PF00650.20 CBZ38797.1 - 1.1e-28 100.0 0.0 1.5e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CBZ38797.1 - 0.072 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Snf7 PF03357.21 CBZ38798.1 - 1.5e-27 96.3 30.0 1.5e-27 96.3 30.0 2.0 1 1 1 2 2 2 1 Snf7 GUCT PF08152.12 CBZ38798.1 - 1.3 9.4 6.8 1.2 9.4 0.6 2.6 1 1 1 2 2 2 0 GUCT (NUC152) domain Glyco_transf_25 PF01755.17 CBZ38799.1 - 8e-11 42.2 0.0 2.5e-10 40.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) NIPSNAP PF07978.13 CBZ38800.1 - 3.5e-14 52.9 0.1 6.9e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 NIPSNAP Transket_pyr PF02779.24 CBZ38801.1 - 5.8e-56 189.0 0.0 2.9e-55 186.7 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CBZ38801.1 - 7.5e-51 172.9 0.0 1.2e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CBZ38801.1 - 2.6e-44 150.6 0.2 4.6e-44 149.8 0.2 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CBZ38801.1 - 2.6e-15 55.7 0.9 6.1e-15 54.5 0.9 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus SMAP PF15477.6 CBZ38802.1 - 4.9e-11 43.4 7.2 4.9e-11 43.4 7.2 2.0 2 1 0 2 2 2 1 Small acidic protein family MID_MedPIWI PF18296.1 CBZ38802.1 - 0.15 11.9 1.4 0.16 11.8 1.4 1.1 1 0 0 1 1 1 0 MID domain of medPIWI LCD1 PF09798.9 CBZ38802.1 - 0.21 10.1 1.7 0.24 9.9 1.7 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF2870 PF11069.8 CBZ38803.1 - 1.2e-24 86.5 0.0 2.8e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Rota_NSP4 PF01452.16 CBZ38804.1 - 0.0092 15.7 1.9 0.018 14.7 1.9 1.4 1 0 0 1 1 1 1 Rotavirus non structural protein DivIC PF04977.15 CBZ38804.1 - 0.026 14.3 0.3 0.026 14.3 0.3 3.4 4 0 0 4 4 4 0 Septum formation initiator DUF3658 PF12395.8 CBZ38804.1 - 0.15 12.0 1.4 6.9 6.6 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function Shugoshin_N PF07558.11 CBZ38804.1 - 0.25 11.2 1.9 0.59 10.1 1.9 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region HMMR_C PF15908.5 CBZ38804.1 - 0.26 11.5 4.9 0.68 10.2 0.0 2.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal YabA PF06156.13 CBZ38804.1 - 0.29 11.8 0.1 0.29 11.8 0.1 2.9 2 1 0 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 CBZ38804.1 - 2 8.6 7.5 5 7.3 0.3 2.7 2 0 0 2 2 2 0 bZIP transcription factor DUF2150 PF09920.9 CBZ38806.1 - 0.0063 16.5 0.3 0.026 14.5 0.0 1.9 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2150) COE1_DBD PF16422.5 CBZ38806.1 - 0.15 11.5 0.1 0.22 10.9 0.1 1.1 1 0 0 1 1 1 0 Transcription factor COE1 DNA-binding domain TPR_1 PF00515.28 CBZ38807.1 - 0.0012 18.5 12.9 0.0016 18.2 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ38807.1 - 0.073 13.2 0.1 0.073 13.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3846 PF12957.7 CBZ38807.1 - 0.12 12.7 0.0 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) TPR_9 PF13371.6 CBZ38807.1 - 0.13 12.5 2.8 0.11 12.7 0.8 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38807.1 - 0.14 11.9 5.2 2.1 8.1 0.1 3.4 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.6 CBZ38807.1 - 0.91 10.2 9.5 2 9.2 5.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SQS_PSY PF00494.19 CBZ38809.1 - 4.9e-13 49.2 0.0 7.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase TetR_C_20 PF17925.1 CBZ38809.1 - 0.055 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain SRP54 PF00448.22 CBZ38810.1 - 3.3e-53 180.3 0.1 7e-53 179.2 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CBZ38810.1 - 1.7e-20 74.1 0.0 3e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 CBZ38810.1 - 1.2e-09 38.3 0.0 3e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_22 PF13401.6 CBZ38810.1 - 1.2e-05 25.5 0.0 5.6e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CBZ38810.1 - 1.6e-05 24.7 0.4 1.6e-05 24.7 0.4 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CBZ38810.1 - 0.00092 18.5 0.1 0.0051 16.1 0.0 2.3 2 1 0 2 2 2 1 Zeta toxin APS_kinase PF01583.20 CBZ38810.1 - 0.0016 18.3 0.1 0.0046 16.9 0.0 1.8 2 0 0 2 2 2 1 Adenylylsulphate kinase NTPase_1 PF03266.15 CBZ38810.1 - 0.0017 18.3 0.0 0.57 10.1 0.0 2.4 2 0 0 2 2 2 1 NTPase MeaB PF03308.16 CBZ38810.1 - 0.0028 16.7 1.3 0.0038 16.2 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CBZ38810.1 - 0.0035 17.7 0.1 0.01 16.2 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 CBZ38810.1 - 0.0063 16.6 0.7 0.3 11.1 0.1 2.8 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 CBZ38810.1 - 0.0074 16.7 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CBZ38810.1 - 0.0083 15.9 0.0 0.12 12.1 0.0 2.7 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 CBZ38810.1 - 0.015 15.4 0.9 0.46 10.6 0.6 3.2 3 1 0 3 3 3 0 50S ribosome-binding GTPase ETF PF01012.21 CBZ38810.1 - 0.017 15.1 0.2 0.17 11.8 0.1 2.3 2 0 0 2 2 2 0 Electron transfer flavoprotein domain RsgA_GTPase PF03193.16 CBZ38810.1 - 0.05 13.5 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase ArsA_ATPase PF02374.15 CBZ38810.1 - 0.055 12.6 0.4 0.17 11.0 0.1 1.9 2 0 0 2 2 2 0 Anion-transporting ATPase DAP3 PF10236.9 CBZ38810.1 - 0.056 12.6 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 CBZ38810.1 - 0.075 12.9 0.2 2.8 7.8 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 CBZ38810.1 - 0.08 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CBZ38810.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Longin PF13774.6 CBZ38810.1 - 0.14 12.3 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 Regulated-SNARE-like domain AAA_23 PF13476.6 CBZ38810.1 - 0.17 12.3 0.2 1.8 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2009 PF09418.10 CBZ38811.1 - 1.6e-161 538.5 0.0 1.9e-161 538.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) PALP PF00291.25 CBZ38812.1 - 7e-61 206.2 0.6 8e-61 206.0 0.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 CBZ38812.1 - 0.0056 16.7 0.5 3.2 7.7 0.2 2.9 2 1 0 2 2 2 2 Zinc-binding dehydrogenase EF-hand_7 PF13499.6 CBZ38815.1 - 2.5e-11 43.9 2.5 5.4e-11 42.8 0.7 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CBZ38815.1 - 5.9e-08 32.4 0.7 0.0015 18.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ38815.1 - 6.7e-06 25.6 0.3 0.0037 17.1 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 CBZ38815.1 - 2e-05 23.8 0.5 0.042 13.4 0.0 3.3 3 1 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 CBZ38815.1 - 0.002 17.6 0.2 0.0076 15.7 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_14 PF17959.1 CBZ38815.1 - 0.044 14.1 0.0 0.091 13.1 0.0 1.5 1 1 1 2 2 2 0 EF-hand domain Miga PF10265.9 CBZ38816.1 - 0.004 16.2 0.8 0.0052 15.8 0.8 1.1 1 0 0 1 1 1 1 Mitoguardin DUF4448 PF14610.6 CBZ38816.1 - 0.009 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Shisa PF13908.6 CBZ38816.1 - 0.013 15.7 0.8 0.029 14.6 0.8 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.6 CBZ38816.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Tmemb_9 PF05434.11 CBZ38816.1 - 0.023 14.6 0.9 0.051 13.5 0.9 1.5 1 0 0 1 1 1 0 TMEM9 DUF4229 PF14012.6 CBZ38816.1 - 0.041 14.0 0.0 0.079 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Adeno_E3_CR2 PF02439.15 CBZ38816.1 - 0.053 13.3 2.6 0.11 12.3 2.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MLANA PF14991.6 CBZ38816.1 - 0.061 13.6 0.1 0.061 13.6 0.1 2.1 2 0 0 2 2 2 0 Protein melan-A FixQ PF05545.11 CBZ38816.1 - 0.068 13.2 0.3 0.14 12.1 0.1 1.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DAP10 PF07213.11 CBZ38816.1 - 0.082 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 DAP10 membrane protein BatD PF13584.6 CBZ38816.1 - 0.099 11.4 0.2 0.2 10.5 0.1 1.4 1 1 1 2 2 2 0 Oxygen tolerance DUF3481 PF11980.8 CBZ38816.1 - 0.14 11.9 4.5 0.22 11.2 4.0 1.6 1 1 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein DUF4330 PF14221.6 CBZ38816.1 - 0.15 12.3 0.2 0.23 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DAG1 PF05454.11 CBZ38816.1 - 0.17 11.3 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) EphA2_TM PF14575.6 CBZ38816.1 - 0.21 12.5 1.4 0.36 11.8 1.4 1.5 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 CBZ38816.1 - 0.98 9.6 8.8 2.3 8.5 8.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) WD40 PF00400.32 CBZ38818.1 - 2.2e-11 44.1 9.7 0.0082 17.0 0.2 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat DUF1619 PF07773.11 CBZ38820.1 - 1.6e-47 163.0 1.1 3.9e-46 158.4 0.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1619) NUDIX PF00293.28 CBZ38821.1 - 8.3e-12 45.3 0.0 1.4e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain EF-hand_1 PF00036.32 CBZ38823.1 - 2.7e-27 92.2 4.9 3.4e-07 29.4 0.8 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CBZ38823.1 - 2.4e-26 92.0 0.8 3.5e-14 53.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ38823.1 - 2.4e-22 76.9 2.2 1.3e-06 27.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CBZ38823.1 - 3.9e-21 74.6 4.3 1.2e-09 37.9 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CBZ38823.1 - 4.8e-14 51.1 7.0 0.00012 21.4 0.9 4.0 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CBZ38823.1 - 6e-08 32.9 1.2 0.0011 19.2 0.1 2.9 2 2 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 CBZ38823.1 - 5.8e-05 23.0 2.3 0.0059 16.6 0.2 2.4 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CBZ38823.1 - 0.0083 16.3 1.7 1.1 9.5 0.3 2.9 2 1 2 4 4 4 2 Dockerin type I domain Caleosin PF05042.13 CBZ38823.1 - 0.17 11.8 0.1 0.7 9.8 0.0 2.0 2 1 0 2 2 2 0 Caleosin related protein Pkinase PF00069.25 CBZ38824.1 - 1e-56 192.2 0.0 9.5e-56 189.1 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38824.1 - 2.1e-29 102.6 0.0 9.4e-29 100.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.25 CBZ38824.1 - 0.00045 20.2 0.0 0.0022 18.0 0.0 2.2 1 0 0 1 1 1 1 PAS fold Kinase-like PF14531.6 CBZ38824.1 - 0.00085 18.7 0.0 0.0066 15.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CBZ38824.1 - 0.0019 17.1 0.0 0.0037 16.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 CBZ38824.1 - 0.0071 16.0 0.0 0.051 13.2 0.0 2.1 2 0 0 2 2 2 1 RIO1 family FTA2 PF13095.6 CBZ38824.1 - 0.0084 15.8 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CBZ38824.1 - 0.0099 15.8 0.0 0.041 13.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.7 CBZ38824.1 - 0.012 15.9 0.0 0.032 14.5 0.0 1.8 1 0 0 1 1 1 0 PAS domain Amastin PF07344.11 CBZ38824.1 - 0.11 12.4 2.6 0.27 11.1 2.6 1.6 1 0 0 1 1 1 0 Amastin surface glycoprotein CLP1_P PF16575.5 CBZ38827.1 - 3.7e-09 36.7 0.0 5.1e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 CBZ38827.1 - 0.0015 18.9 0.0 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 FtsK_SpoIIIE PF01580.18 CBZ38827.1 - 0.052 12.9 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family CLP1_N PF16573.5 CBZ38827.1 - 0.096 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal beta-sandwich domain of polyadenylation factor DUF498 PF04430.14 CBZ38828.1 - 2.2e-19 69.5 0.0 4.5e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) HA PF03457.14 CBZ38828.1 - 0.051 13.9 0.4 0.48 10.8 0.0 2.6 2 0 0 2 2 2 0 Helicase associated domain tRNA_int_endo PF01974.17 CBZ38829.1 - 2.3e-16 59.6 0.0 3.7e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Ribosomal_L34e PF01199.18 CBZ38830.1 - 8.5e-27 93.3 2.4 8.5e-27 93.3 2.4 2.2 2 1 0 2 2 2 1 Ribosomal protein L34e RecA PF00154.21 CBZ38830.1 - 0.024 14.1 1.8 0.032 13.7 1.8 1.1 1 0 0 1 1 1 0 recA bacterial DNA recombination protein PGM_PMM_III PF02880.16 CBZ38830.1 - 0.2 11.8 0.9 0.36 11.0 0.3 1.7 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Ribosomal_S27e PF01667.17 CBZ38831.1 - 8.1e-22 76.7 3.2 9.9e-22 76.4 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 FYVE_2 PF02318.16 CBZ38831.1 - 0.014 15.6 0.8 0.016 15.4 0.8 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Zn_Tnp_IS1595 PF12760.7 CBZ38831.1 - 0.025 14.5 1.8 0.04 13.9 1.8 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.6 CBZ38831.1 - 0.13 12.2 4.6 2.9 7.9 4.6 2.4 1 1 0 1 1 1 0 zinc-ribbon domain HypA PF01155.19 CBZ38831.1 - 0.15 12.1 1.8 0.17 11.9 1.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 CBZ38831.1 - 1.3 9.0 6.0 11 6.0 6.3 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_L1 PF00687.21 CBZ38832.1 - 5.1e-08 32.9 0.1 5.3e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family NAC PF01849.18 CBZ38833.1 - 1.3e-16 60.3 0.0 1.8e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 NAC domain Carbam_trans_N PF02543.15 CBZ38833.1 - 0.067 12.8 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus MORN PF02493.20 CBZ38834.1 - 1.1e-16 59.7 60.5 6.3e-05 22.6 1.2 9.4 10 0 0 10 10 10 7 MORN repeat DUF2766 PF10964.8 CBZ38834.1 - 0.022 14.7 0.0 0.072 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2766) DUF448 PF04296.13 CBZ38834.1 - 0.043 13.7 5.2 11 6.0 0.0 4.9 4 3 1 5 5 5 0 Protein of unknown function (DUF448) PilJ_C PF18223.1 CBZ38834.1 - 2.9 8.4 6.6 5.2 7.6 0.1 3.2 2 2 1 3 3 3 0 Pili PilJ C-terminal domain CH PF00307.31 CBZ38835.1 - 0.00048 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain IMS PF00817.20 CBZ38835.1 - 0.002 18.1 0.9 0.0057 16.7 0.9 1.7 1 0 0 1 1 1 1 impB/mucB/samB family ADIP PF11559.8 CBZ38835.1 - 0.013 15.6 5.2 0.013 15.6 5.2 3.3 5 0 0 5 5 5 0 Afadin- and alpha -actinin-Binding CAMSAP_CH PF11971.8 CBZ38835.1 - 0.091 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain BRE1 PF08647.11 CBZ38835.1 - 1.3 9.1 7.0 36 4.5 4.3 2.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DSBA PF01323.20 CBZ38835.1 - 6.8 6.4 9.9 0.33 10.7 3.3 2.1 2 1 0 2 2 2 0 DSBA-like thioredoxin domain GCV_T PF01571.21 CBZ38836.1 - 1.3e-24 87.0 0.1 1.4e-24 86.9 0.1 1.0 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T PF01571.21 CBZ38837.1 - 1.5e-79 267.1 0.4 1.8e-79 266.8 0.4 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CBZ38837.1 - 6.2e-19 67.7 0.4 1.4e-18 66.6 0.2 1.7 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Pico_P1A PF02226.16 CBZ38837.1 - 0.063 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) TolA_bind_tri PF16331.5 CBZ38838.1 - 0.0079 16.2 1.9 0.015 15.4 1.9 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation HisKA_3 PF07730.13 CBZ38838.1 - 0.015 15.8 1.0 0.03 14.8 1.0 1.5 1 0 0 1 1 1 0 Histidine kinase Uds1 PF15456.6 CBZ38838.1 - 0.084 13.0 2.8 0.11 12.7 2.8 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Gon7 PF08738.10 CBZ38838.1 - 0.09 12.9 0.1 12 6.1 0.0 2.1 2 0 0 2 2 2 0 Gon7 family DUF1690 PF07956.11 CBZ38838.1 - 0.19 12.1 2.3 0.19 12.1 0.9 1.7 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) bZIP_2 PF07716.15 CBZ38838.1 - 0.25 11.4 8.1 1.2 9.3 3.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper zf-C3HC4_3 PF13920.6 CBZ38839.1 - 1.1e-18 66.8 31.8 3.5e-13 49.2 11.8 4.3 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CBZ38839.1 - 3.6e-06 26.7 28.3 1e-05 25.3 9.9 3.6 3 1 1 4 4 4 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CBZ38839.1 - 0.00045 20.1 12.3 0.00045 20.1 12.3 3.9 4 0 0 4 4 4 2 zinc-RING finger domain zf-RING_2 PF13639.6 CBZ38839.1 - 0.0092 16.3 13.2 0.0092 16.3 13.2 4.5 4 1 0 4 4 4 2 Ring finger domain ADK_lid PF05191.14 CBZ38839.1 - 0.21 11.6 0.0 0.21 11.6 0.0 4.1 4 2 0 4 4 4 0 Adenylate kinase, active site lid HGTP_anticodon PF03129.20 CBZ38840.1 - 5e-18 65.0 0.0 9.8e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CBZ38840.1 - 6.2e-07 29.6 0.0 3e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Snf7 PF03357.21 CBZ38841.1 - 2.7e-29 102.0 32.2 2.7e-29 102.0 32.2 1.5 2 0 0 2 2 2 1 Snf7 SOG2 PF10428.9 CBZ38841.1 - 0.016 14.4 3.6 0.018 14.2 3.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Exonuc_VII_L PF02601.15 CBZ38841.1 - 5.6 6.4 12.5 7.4 6.0 12.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 CBZ38841.1 - 6.6 6.0 18.4 2.3 7.5 15.8 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HAP2-GCS1 PF10699.9 CBZ38842.1 - 7.9e-14 51.4 0.1 3.3e-13 49.4 0.1 2.2 2 0 0 2 2 2 1 Male gamete fusion factor Big_1 PF02369.16 CBZ38842.1 - 0.47 10.5 3.6 0.45 10.6 0.1 2.7 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) THOC7 PF05615.13 CBZ38843.1 - 0.04 14.2 3.5 0.067 13.5 3.5 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Flot PF15975.5 CBZ38843.1 - 0.2 11.9 3.8 0.51 10.5 2.2 2.4 2 0 0 2 2 2 0 Flotillin WD40 PF00400.32 CBZ38844.1 - 3.5e-14 52.9 2.8 0.00034 21.4 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ38844.1 - 3.4e-09 36.9 0.0 1.5 9.2 0.0 5.2 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CBZ38844.1 - 0.028 13.4 0.0 0.13 11.2 0.0 2.1 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MAM33 PF02330.16 CBZ38845.1 - 4.9e-05 23.4 0.0 0.0003 20.8 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial glycoprotein AdoHcyase PF05221.17 CBZ38847.1 - 1.4e-130 434.8 0.0 1.6e-73 247.5 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CBZ38847.1 - 2.3e-86 287.9 1.9 3.3e-86 287.4 1.9 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CBZ38847.1 - 2.5e-10 40.0 0.0 5.1e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CBZ38847.1 - 3.3e-05 23.5 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CBZ38847.1 - 0.00016 21.9 0.2 0.0008 19.7 0.2 2.3 2 1 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 CBZ38847.1 - 0.00072 20.0 0.1 0.0018 18.7 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding PALP PF00291.25 CBZ38847.1 - 0.022 14.2 0.5 0.065 12.6 0.2 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme ELFV_dehydrog PF00208.21 CBZ38847.1 - 0.046 13.4 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_nitro PF00148.19 CBZ38847.1 - 0.071 11.8 0.0 0.13 11.0 0.0 1.5 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase DUF2244 PF10003.9 CBZ38848.1 - 9.5 5.9 9.3 19 4.9 7.0 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Telomerase_RBD PF12009.8 CBZ38849.1 - 1.8e-21 76.7 0.1 3.1e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CBZ38849.1 - 0.0011 18.6 0.0 0.0028 17.2 0.0 1.6 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cast PF10174.9 CBZ38851.1 - 0.00027 19.3 12.9 0.00027 19.3 12.9 1.6 1 1 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Atg14 PF10186.9 CBZ38851.1 - 0.00097 18.3 6.4 0.0058 15.8 0.2 2.2 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 IFT46_B_C PF12317.8 CBZ38851.1 - 0.055 13.2 0.2 0.23 11.2 0.6 1.9 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Hemagglutinin PF00509.18 CBZ38851.1 - 0.092 11.1 0.6 0.12 10.8 0.6 1.1 1 0 0 1 1 1 0 Haemagglutinin Bacillus_HBL PF05791.11 CBZ38851.1 - 0.18 11.6 2.9 0.33 10.7 0.2 2.5 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Fez1 PF06818.15 CBZ38851.1 - 0.5 10.8 16.4 0.021 15.3 7.5 2.2 1 1 1 2 2 2 0 Fez1 TFIIF_beta_N PF17683.1 CBZ38851.1 - 1.8 9.3 5.0 37 5.0 5.0 2.2 1 1 0 1 1 1 0 TFIIF, beta subunit N-terminus TACC_C PF05010.14 CBZ38851.1 - 4.9 6.9 16.9 0.078 12.8 6.3 2.8 2 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FlaC_arch PF05377.11 CBZ38851.1 - 5.8 7.4 10.9 1.2 9.6 0.4 4.2 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) Phage_holin_2_1 PF04971.12 CBZ38853.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S Herpes_UL6 PF01763.16 CBZ38853.1 - 0.23 9.9 4.4 0.38 9.2 4.4 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like CDC73_C PF05179.14 CBZ38854.1 - 1.6e-32 112.3 0.0 2.3e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal Proteasome PF00227.26 CBZ38855.1 - 7.7e-25 87.5 0.3 3e-24 85.5 0.3 1.8 1 1 0 1 1 1 1 Proteasome subunit Fimbrial_PilY2 PF14481.6 CBZ38855.1 - 0.14 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 NTP_transf_2 PF01909.23 CBZ38856.1 - 5.5e-07 29.8 0.0 9.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CBZ38856.1 - 0.00061 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase Rieske PF00355.26 CBZ38857.1 - 0.0069 16.3 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain V-SNARE_C PF12352.8 CBZ38859.1 - 1.3e-06 28.6 1.1 1.3e-06 28.6 1.1 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SSFA2_C PF14723.6 CBZ38859.1 - 0.019 14.9 0.2 0.019 14.9 0.2 2.1 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus RD3 PF14473.6 CBZ38859.1 - 0.15 11.9 1.1 0.74 9.7 0.1 2.2 2 0 0 2 2 2 0 RD3 protein Peptidase_M14 PF00246.24 CBZ38860.1 - 2.6e-14 53.7 0.0 1.3e-13 51.4 0.0 2.1 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CBZ38860.1 - 8.9e-07 28.3 0.1 1.4e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Pepdidase_M14_N PF18027.1 CBZ38860.1 - 1.3e-06 28.8 0.0 2.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain TPR_12 PF13424.6 CBZ38861.1 - 0.00078 19.7 9.4 0.14 12.5 0.7 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CBZ38861.1 - 0.0021 18.7 14.2 0.56 10.9 1.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 CBZ38861.1 - 0.0097 15.3 1.1 0.022 14.2 1.1 1.6 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.17 CBZ38861.1 - 0.01 15.9 16.1 0.69 10.2 2.3 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ38861.1 - 0.016 15.0 6.3 11 6.1 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CBZ38861.1 - 0.053 13.6 5.9 4.5 7.5 1.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Strep_SA_rep PF06696.11 CBZ38861.1 - 0.23 11.5 11.1 3 7.9 3.8 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF913 PF06025.12 CBZ38861.1 - 0.25 10.3 2.5 0.4 9.6 2.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TPR_8 PF13181.6 CBZ38861.1 - 0.75 10.2 3.0 5.4 7.5 0.5 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat SURF2 PF05477.11 CBZ38861.1 - 6.1 6.5 9.5 12 5.6 9.5 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) SKA1 PF07160.12 CBZ38861.1 - 7.9 6.2 7.1 7.1 6.4 4.6 2.0 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 TatD_DNase PF01026.21 CBZ38862.1 - 1.4e-24 86.8 0.0 5.1e-24 85.0 0.0 1.8 2 0 0 2 2 2 1 TatD related DNase RCC1 PF00415.18 CBZ38863.1 - 7.8e-40 135.3 10.2 2.6e-09 37.5 0.1 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CBZ38863.1 - 1.3e-19 69.5 25.0 1.1e-07 31.4 3.0 7.8 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat His_Phos_1 PF00300.22 CBZ38864.1 - 3.8e-13 49.6 3.3 4e-05 23.4 0.1 3.4 1 1 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) DUF501 PF04417.12 CBZ38864.1 - 0.0076 16.1 0.3 0.012 15.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF501) CREPT PF16566.5 CBZ38864.1 - 0.12 12.5 1.8 0.24 11.6 1.8 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour IQ PF00612.27 CBZ38865.1 - 1.5e-11 43.0 14.6 0.00018 21.0 0.2 4.1 4 0 0 4 4 4 3 IQ calmodulin-binding motif Glyco_hydro_31 PF01055.26 CBZ38867.1 - 7.8e-51 173.6 0.0 1.4e-50 172.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 MyTH4 PF00784.17 CBZ38868.1 - 0.11 13.0 0.2 2.3 8.8 0.0 2.7 2 1 0 2 2 2 0 MyTH4 domain Tnp_22_dsRBD PF17490.2 CBZ38868.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 L1 transposable element dsRBD-like domain Amastin PF07344.11 CBZ38870.1 - 1.1e-06 28.6 6.2 1.1e-06 28.6 6.2 2.1 2 0 0 2 2 2 1 Amastin surface glycoprotein Amastin PF07344.11 CBZ38871.1 - 1.7e-13 50.7 6.9 2.7e-13 50.1 6.7 1.4 1 1 0 1 1 1 1 Amastin surface glycoprotein PMP22_Claudin PF00822.20 CBZ38871.1 - 0.13 12.1 8.3 0.4 10.5 8.3 1.8 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family DUF2207 PF09972.9 CBZ38871.1 - 0.89 8.2 5.8 0.43 9.3 0.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TFIIS_C PF01096.18 CBZ38872.1 - 9.3e-11 41.4 8.4 9.3e-11 41.4 8.4 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF1451 PF07295.11 CBZ38872.1 - 0.0059 16.6 0.6 0.0059 16.6 0.6 2.2 3 0 0 3 3 3 1 Zinc-ribbon containing domain Baculo_LEF5_C PF11792.8 CBZ38872.1 - 0.027 14.2 1.4 0.086 12.5 1.4 1.9 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Sar8_2 PF03058.14 CBZ38872.1 - 0.044 14.3 0.4 0.044 14.3 0.4 2.3 2 1 0 2 2 2 0 Sar8.2 family Trm112p PF03966.16 CBZ38872.1 - 0.089 13.4 0.0 0.19 12.3 0.0 1.6 1 0 0 1 1 1 0 Trm112p-like protein DUF3255 PF11631.8 CBZ38872.1 - 0.17 11.8 0.1 0.51 10.2 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3255) RNA_POL_M_15KD PF02150.16 CBZ38872.1 - 0.3 11.0 5.1 18 5.3 0.1 3.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Phage_lysozyme PF00959.19 CBZ38873.1 - 0.075 13.5 0.0 0.33 11.4 0.0 2.1 1 0 0 1 1 1 0 Phage lysozyme Katanin_con80 PF13925.6 CBZ38873.1 - 0.1 12.7 6.6 0.032 14.3 1.8 2.4 2 1 0 2 2 2 0 con80 domain of Katanin ADH_zinc_N PF00107.26 CBZ38875.1 - 1.5e-29 102.6 0.0 2.8e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CBZ38875.1 - 1.2e-17 65.2 0.0 2.4e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CBZ38875.1 - 1.6e-11 44.0 0.0 5.4e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 CBZ38875.1 - 0.011 16.2 0.1 0.44 11.0 0.0 2.4 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 CBZ38875.1 - 0.042 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain PK_C PF02887.16 CBZ38875.1 - 0.075 13.3 0.4 0.28 11.4 0.2 2.0 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain Cpn10 PF00166.21 CBZ38875.1 - 0.093 12.8 0.1 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit Glycos_transf_4 PF00953.21 CBZ38876.1 - 2.2e-49 167.5 4.9 2.2e-49 167.5 4.9 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 4 Seadorna_Vp10 PF07322.11 CBZ38876.1 - 0.031 13.7 0.0 0.074 12.4 0.0 1.5 2 0 0 2 2 2 0 Seadornavirus Vp10 VIT1 PF01988.19 CBZ38876.1 - 0.7 9.7 3.5 9.3 6.0 0.2 3.2 3 0 0 3 3 3 0 VIT family Sld5 PF05916.11 CBZ38877.1 - 7.7e-18 65.0 0.0 1.5e-17 64.0 0.0 1.5 2 0 0 2 2 2 1 GINS complex protein Arrestin_N PF00339.29 CBZ38878.1 - 3.1e-07 30.5 0.0 1.9e-05 24.7 0.0 2.7 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CBZ38878.1 - 2.3e-05 24.2 0.0 0.0001 22.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin_N terminal like Spo0M PF07070.11 CBZ38878.1 - 0.00086 18.9 0.2 0.0029 17.2 0.1 1.9 3 0 0 3 3 3 1 SpoOM protein Utp21 PF04192.12 CBZ38879.1 - 8.8e-24 84.3 0.1 1.4e-23 83.7 0.1 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 CBZ38879.1 - 2.3e-15 56.7 8.6 0.0011 19.8 0.0 9.0 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ38879.1 - 6e-13 48.9 0.2 4.4e-05 23.7 0.0 5.2 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CBZ38879.1 - 1.4e-06 28.1 4.2 0.0015 18.1 0.4 3.2 2 2 0 2 2 2 2 PQQ-like domain Nup160 PF11715.8 CBZ38879.1 - 0.00017 20.4 1.1 0.036 12.7 0.0 3.7 3 1 1 4 4 4 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CBZ38879.1 - 0.0045 15.9 6.2 0.16 10.8 0.2 3.8 3 1 1 4 4 4 2 Partner and localizer of BRCA2 WD40 domain Utp12 PF04003.12 CBZ38879.1 - 0.027 14.8 0.0 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Hira PF07569.11 CBZ38879.1 - 0.05 13.3 0.3 9.7 5.8 0.1 3.7 3 1 0 3 3 3 0 TUP1-like enhancer of split HU-CCDC81_euk_2 PF18289.1 CBZ38879.1 - 0.13 12.4 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 2 LRR_6 PF13516.6 CBZ38881.1 - 2.9e-48 157.8 41.4 0.0002 21.1 0.1 18.8 20 0 0 20 20 20 12 Leucine Rich repeat LRR_4 PF12799.7 CBZ38881.1 - 5.3e-17 61.6 29.3 0.00048 20.5 0.0 12.1 12 2 1 13 13 13 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CBZ38881.1 - 1.6e-07 30.9 15.7 1.7e+02 3.4 0.0 14.6 20 0 0 20 20 20 0 Leucine Rich Repeat LRR_8 PF13855.6 CBZ38881.1 - 0.00093 18.9 34.9 0.082 12.7 0.2 12.3 11 5 1 12 12 12 2 Leucine rich repeat WD40 PF00400.32 CBZ38882.1 - 4.9e-05 24.0 0.8 7.5 7.6 0.1 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ38882.1 - 0.0044 17.3 0.0 1.5 9.2 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CBZ38882.1 - 0.13 12.7 0.8 12 6.5 0.1 3.7 3 0 0 3 3 3 0 PQQ-like domain Pkinase PF00069.25 CBZ38883.1 - 2.5e-46 158.2 0.0 2.4e-23 82.8 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38883.1 - 3e-18 66.0 0.0 4.1e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CBZ38883.1 - 0.19 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4238 PF14022.6 CBZ38884.1 - 0.98 8.9 5.3 1.5 8.3 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Cor1 PF04803.12 CBZ38884.1 - 8.5 6.6 15.3 0.4 10.9 8.5 2.2 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region TPR_14 PF13428.6 CBZ38886.1 - 1.1e-09 38.2 56.2 0.035 14.9 1.3 12.6 9 3 4 13 13 12 7 Tetratricopeptide repeat HAT PF02184.16 CBZ38886.1 - 1.4e-06 28.1 16.9 0.11 12.5 0.2 5.7 6 0 0 6 6 6 3 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 CBZ38886.1 - 3.6e-05 24.2 15.5 0.24 11.9 0.1 5.9 6 1 0 6 6 5 2 Tetratricopeptide repeat DUF2063 PF09836.9 CBZ38886.1 - 0.0022 18.2 1.5 0.0071 16.6 0.4 2.5 2 0 0 2 2 2 1 Putative DNA-binding domain CCP_MauG PF03150.14 CBZ38886.1 - 0.018 15.7 0.8 0.18 12.4 0.0 2.9 2 2 0 2 2 2 0 Di-haem cytochrome c peroxidase TPR_16 PF13432.6 CBZ38886.1 - 0.02 15.6 31.6 1.7 9.3 0.9 7.4 5 2 1 6 6 6 0 Tetratricopeptide repeat NRDE-2 PF08424.10 CBZ38886.1 - 0.02 14.0 3.1 0.25 10.4 0.1 3.2 2 2 0 3 3 3 0 NRDE-2, necessary for RNA interference TPR_9 PF13371.6 CBZ38886.1 - 0.022 14.9 24.8 0.043 14.0 1.2 6.0 5 1 0 5 5 5 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CBZ38886.1 - 0.031 14.3 4.3 2.4 8.2 0.1 5.0 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 VitK2_biosynth PF02621.14 CBZ38886.1 - 0.91 9.0 9.1 0.095 12.2 0.5 3.0 3 0 0 3 3 3 0 Menaquinone biosynthesis TPR_17 PF13431.6 CBZ38886.1 - 3.4 8.2 5.6 1.4e+02 3.2 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat Arf PF00025.21 CBZ38887.1 - 2.4e-11 43.4 0.0 4.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PH PF00169.29 CBZ38887.1 - 2.1e-08 34.6 0.1 5e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CBZ38887.1 - 0.037 14.3 0.2 0.14 12.4 0.2 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain MMR_HSR1 PF01926.23 CBZ38887.1 - 0.13 12.4 0.0 0.66 10.1 0.0 2.3 2 1 0 2 2 2 0 50S ribosome-binding GTPase CHAP PF05257.16 CBZ38888.1 - 9.1e-12 45.4 0.3 4.3e-11 43.2 0.1 2.3 2 0 0 2 2 2 1 CHAP domain SET PF00856.28 CBZ38889.1 - 2.5e-08 34.5 0.0 1.6e-07 31.9 0.0 2.2 1 1 0 1 1 1 1 SET domain DUF3618 PF12277.8 CBZ38889.1 - 0.73 10.1 5.8 4.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) C2 PF00168.30 CBZ38890.1 - 3e-45 152.7 0.0 2.5e-12 47.0 0.0 8.4 9 1 0 9 9 9 6 C2 domain CEP76-C2 PF15627.6 CBZ38890.1 - 0.0017 18.0 0.2 0.15 11.7 0.0 3.1 3 0 0 3 3 3 1 CEP76 C2 domain C2 PF00168.30 CBZ38891.1 - 1.1e-16 61.0 0.0 0.0074 16.6 0.0 4.5 4 0 0 4 4 4 4 C2 domain AAA PF00004.29 CBZ38894.1 - 6.1e-44 149.6 0.0 1.4e-43 148.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CBZ38894.1 - 6.3e-15 54.7 0.3 2e-14 53.1 0.1 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 CBZ38894.1 - 2.9e-07 30.6 0.0 1.1e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 CBZ38894.1 - 4.6e-07 29.7 0.7 1e-06 28.6 0.7 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CBZ38894.1 - 9e-07 29.2 0.0 2.4e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CBZ38894.1 - 2.5e-06 28.0 0.3 0.0001 22.8 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CBZ38894.1 - 2.1e-05 24.3 0.0 5.4e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CBZ38894.1 - 2.1e-05 24.8 2.5 0.0093 16.2 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 CBZ38894.1 - 0.00037 21.0 0.2 0.022 15.3 0.0 2.8 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 CBZ38894.1 - 0.0013 18.5 0.0 0.0037 17.0 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CBZ38894.1 - 0.0016 18.6 0.0 0.0037 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CBZ38894.1 - 0.0029 16.9 0.0 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 CBZ38894.1 - 0.003 16.9 0.2 0.1 11.9 0.0 2.6 3 0 0 3 3 3 1 KaiC AAA_28 PF13521.6 CBZ38894.1 - 0.0053 17.0 0.2 0.016 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CBZ38894.1 - 0.0077 15.4 0.0 0.41 9.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_3 PF07726.11 CBZ38894.1 - 0.0077 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CBZ38894.1 - 0.008 15.9 0.9 0.055 13.2 0.1 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CBZ38894.1 - 0.0081 15.6 0.0 0.028 13.8 0.0 1.8 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CBZ38894.1 - 0.0092 15.6 0.3 0.17 11.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CBZ38894.1 - 0.012 15.9 0.0 0.026 14.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CBZ38894.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CBZ38894.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CBZ38894.1 - 0.02 14.9 0.0 0.069 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain APG6_N PF17675.1 CBZ38894.1 - 0.022 15.3 0.2 0.046 14.3 0.2 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region ADIP PF11559.8 CBZ38894.1 - 0.022 14.8 1.4 0.045 13.8 1.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF815 PF05673.13 CBZ38894.1 - 0.023 13.9 0.1 0.066 12.4 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CBZ38894.1 - 0.025 14.3 0.1 0.066 12.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CBZ38894.1 - 0.025 13.8 0.5 0.16 11.2 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 CBZ38894.1 - 0.027 14.3 0.1 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CBZ38894.1 - 0.029 13.8 0.1 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.17 CBZ38894.1 - 0.048 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4618 PF15397.6 CBZ38894.1 - 0.062 12.7 1.0 0.17 11.3 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) AAA_19 PF13245.6 CBZ38894.1 - 0.073 13.4 2.6 0.65 10.3 0.0 2.8 2 1 1 3 3 3 0 AAA domain DUF2968 PF11180.8 CBZ38894.1 - 0.48 10.0 3.3 0.36 10.5 1.7 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2968) HECT PF00632.25 CBZ38895.1 - 4.9e-58 197.0 0.0 7.1e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HECT PF00632.25 CBZ38896.1 - 4.9e-58 197.0 0.0 7.1e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AOX PF01786.17 CBZ38897.1 - 3.5e-79 265.4 0.0 4.2e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase GCP_C_terminal PF04130.13 CBZ38898.1 - 4.3e-42 144.6 0.2 8.4e-42 143.7 0.2 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CBZ38898.1 - 1.5e-24 87.2 0.0 4.1e-24 85.8 0.0 1.9 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF309 PF03745.14 CBZ38898.1 - 0.011 15.4 0.3 0.12 12.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF309) DEAD PF00270.29 CBZ38899.1 - 1.1e-31 110.0 0.3 6e-31 107.6 0.1 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CBZ38899.1 - 8.5e-31 106.6 0.3 4.7e-29 101.0 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.14 CBZ38899.1 - 0.0084 15.4 0.2 0.38 10.0 0.2 2.7 1 1 0 1 1 1 1 SecA DEAD-like domain ResIII PF04851.15 CBZ38899.1 - 0.02 14.9 0.7 0.69 9.9 0.0 3.2 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CBZ38899.1 - 0.29 11.4 2.6 41 4.4 0.0 3.6 4 1 0 4 4 4 0 AAA domain Asparaginase PF00710.20 CBZ38902.1 - 1.8e-35 122.2 0.0 2.4e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CBZ38902.1 - 1.1e-24 86.9 0.0 2.2e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain SinI PF08671.10 CBZ38902.1 - 0.2 11.5 0.2 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 Anti-repressor SinI TPR_19 PF14559.6 CBZ38903.1 - 2.6e-05 24.6 0.1 0.0073 16.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CBZ38903.1 - 0.00034 20.8 6.6 0.0018 18.5 0.7 3.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ38903.1 - 0.0021 18.1 0.2 0.0021 18.1 0.2 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CBZ38903.1 - 0.0024 18.0 1.2 0.17 12.1 0.1 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CBZ38903.1 - 0.003 17.6 0.6 0.014 15.5 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ38903.1 - 0.0036 18.0 2.1 2.8 9.0 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CBZ38903.1 - 0.008 16.0 1.7 0.046 13.6 0.3 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CBZ38903.1 - 0.014 15.0 0.3 0.075 12.7 0.2 2.4 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 CBZ38903.1 - 0.02 15.5 0.7 0.18 12.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 CBZ38903.1 - 0.033 14.8 0.8 0.12 13.0 0.8 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CBZ38903.1 - 0.057 13.7 0.1 0.2 12.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2193 PF09959.9 CBZ38903.1 - 0.11 10.9 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) TPR_10 PF13374.6 CBZ38903.1 - 0.16 11.9 0.3 0.54 10.2 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Peptidase_M3 PF01432.20 CBZ38904.1 - 5.1e-73 246.9 0.3 2.1e-58 198.7 0.3 2.0 2 0 0 2 2 2 2 Peptidase family M3 Peptidase_M32 PF02074.15 CBZ38904.1 - 0.0031 16.4 0.3 0.0072 15.1 0.3 1.5 2 0 0 2 2 2 1 Carboxypeptidase Taq (M32) metallopeptidase DnaJ PF00226.31 CBZ38906.1 - 1.6e-22 79.4 0.2 4.1e-22 78.1 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain Spectrin_like PF18373.1 CBZ38906.1 - 1.6 8.9 4.3 9 6.4 0.4 3.1 2 1 1 3 3 3 0 Spectrin like domain Aa_trans PF01490.18 CBZ38907.1 - 1.5e-43 149.1 0.4 1.5e-35 122.7 0.0 2.6 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein TMEM107 PF14995.6 CBZ38907.1 - 0.054 13.9 0.3 0.054 13.9 0.3 2.9 3 0 0 3 3 3 0 Transmembrane protein FAM209 PF15206.6 CBZ38907.1 - 0.26 11.1 0.1 0.52 10.1 0.1 1.4 1 0 0 1 1 1 0 FAM209 family MTS PF05175.14 CBZ38908.1 - 5.2e-12 45.6 0.0 2.5e-09 36.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_31 PF13847.6 CBZ38908.1 - 2e-08 34.2 0.0 4.4e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ38908.1 - 1.8e-07 31.8 0.0 5.1e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CBZ38908.1 - 3.3e-06 26.7 0.0 6.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 CBZ38908.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 CBZ38908.1 - 0.002 17.9 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.12 CBZ38908.1 - 0.0037 17.9 0.0 0.0088 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ38908.1 - 0.011 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ38908.1 - 0.018 15.8 0.0 0.045 14.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 CBZ38908.1 - 0.058 13.1 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 CBZ38908.1 - 0.084 12.8 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 CBZ38908.1 - 0.094 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 CBZ38908.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TRM PF02005.16 CBZ38908.1 - 0.21 10.7 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DUF2870 PF11069.8 CBZ38909.1 - 1.3e-36 124.8 0.1 3e-36 123.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Nup54_C PF18437.1 CBZ38909.1 - 0.05 13.5 0.4 0.1 12.5 0.4 1.5 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain BBS2_C PF14782.6 CBZ38909.1 - 0.083 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Ribosomal_L18 PF17135.4 CBZ38910.1 - 2.5e-74 248.7 3.5 2.9e-74 248.5 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CBZ38910.1 - 0.00012 22.8 0.1 0.0004 21.1 0.1 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A ABC1 PF03109.16 CBZ38912.1 - 2.1e-26 92.4 0.0 3.6e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family AalphaY_MDB PF04611.12 CBZ38912.1 - 0.014 15.4 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Pkinase PF00069.25 CBZ38912.1 - 0.045 13.1 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Alpha_kinase PF02816.18 CBZ38913.1 - 7.4e-51 172.9 0.2 9.5e-51 172.5 0.2 1.1 1 0 0 1 1 1 1 Alpha-kinase family Alpha_kinase PF02816.18 CBZ38914.1 - 1.7e-78 263.0 0.1 1.6e-39 135.9 0.0 3.4 3 0 0 3 3 3 3 Alpha-kinase family Alpha_kinase PF02816.18 CBZ38915.1 - 7.6e-57 192.4 0.3 9.7e-57 192.1 0.3 1.1 1 0 0 1 1 1 1 Alpha-kinase family PSP1 PF04468.12 CBZ38916.1 - 8.3e-28 96.5 0.7 1.3e-27 95.9 0.7 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region BBS2_N PF14781.6 CBZ38918.1 - 0.062 13.2 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal zf-HC5HC2H PF13771.6 CBZ38919.1 - 1.5e-07 31.6 6.7 1.5e-07 31.6 6.7 3.4 3 1 1 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CBZ38919.1 - 9.5e-06 25.8 18.8 3e-05 24.2 11.5 3.0 2 1 0 2 2 2 2 PHD-zinc-finger like domain C1_1 PF00130.22 CBZ38919.1 - 0.058 13.3 0.5 0.058 13.3 0.5 4.6 4 1 1 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Transmemb_17 PF09799.9 CBZ38920.1 - 2.7e-17 63.3 13.4 3.7e-17 62.8 13.4 1.2 1 0 0 1 1 1 1 Predicted membrane protein HTH_Tnp_1 PF01527.20 CBZ38922.1 - 0.14 12.4 1.5 4.2 7.7 0.4 3.0 3 0 0 3 3 3 0 Transposase Ham1p_like PF01725.16 CBZ38923.1 - 2.9e-47 161.0 0.0 3.3e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Peptidase_S9 PF00326.21 CBZ38924.1 - 4.8e-07 29.5 0.4 1.4e-05 24.7 0.1 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 CBZ38924.1 - 9e-07 28.6 2.0 3.4e-06 26.7 2.1 1.8 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 CBZ38924.1 - 1.4e-06 28.3 0.1 1.2e-05 25.2 0.1 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.20 CBZ38924.1 - 2.8e-05 23.9 0.0 0.00028 20.6 0.0 2.2 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 CBZ38924.1 - 0.038 13.8 0.1 0.076 12.9 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold FSH1 PF03959.13 CBZ38924.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 CBZ38924.1 - 0.06 12.6 0.1 15 4.8 0.0 3.0 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 CBZ38924.1 - 5.4 6.5 5.4 5.7 6.4 0.1 3.0 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) EVC2_like PF12297.8 CBZ38924.1 - 7.7 5.1 6.2 11 4.5 6.2 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein RL10P_insert PF17777.1 CBZ38925.1 - 1e-24 86.3 0.0 1.7e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CBZ38925.1 - 3.6e-20 72.0 0.0 5.6e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3577 PF12101.8 CBZ38925.1 - 0.032 14.0 0.1 0.05 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3577) VPS9 PF02204.18 CBZ38926.1 - 4.2e-30 104.0 0.0 1e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Phage-scaffold PF09306.10 CBZ38926.1 - 0.028 13.8 0.2 0.054 12.8 0.2 1.4 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein Prok-TraM PF09228.10 CBZ38926.1 - 0.067 13.6 0.6 12 6.3 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic Transcriptional repressor TraM HALZ PF02183.18 CBZ38927.1 - 0.038 14.2 0.1 0.038 14.2 0.1 2.6 3 1 0 3 3 2 0 Homeobox associated leucine zipper SKA2 PF16740.5 CBZ38927.1 - 0.043 13.6 4.5 0.07 12.9 4.5 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Golgin_A5 PF09787.9 CBZ38927.1 - 0.051 13.0 7.2 0.24 10.8 7.3 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 TMF_DNA_bd PF12329.8 CBZ38927.1 - 0.054 13.5 8.4 0.51 10.4 0.2 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 CBZ38927.1 - 0.061 13.5 0.6 0.081 13.1 0.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 CBZ38927.1 - 0.08 11.6 2.4 0.1 11.2 2.4 1.1 1 0 0 1 1 1 0 AAA domain ZapB PF06005.12 CBZ38927.1 - 0.11 12.9 11.0 13 6.4 3.5 2.2 1 1 1 2 2 2 0 Cell division protein ZapB Cnn_1N PF07989.11 CBZ38927.1 - 0.15 12.2 6.0 5.6 7.2 2.0 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 GIT_CC PF16559.5 CBZ38927.1 - 0.16 11.8 5.3 0.23 11.3 0.3 2.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlxA PF14282.6 CBZ38927.1 - 0.23 11.4 3.8 0.2 11.6 1.1 2.0 1 1 1 2 2 2 0 FlxA-like protein Atg14 PF10186.9 CBZ38927.1 - 0.23 10.5 6.1 0.43 9.6 6.1 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 CBZ38927.1 - 0.24 11.7 5.4 0.32 11.3 5.4 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TetR_C_24 PF17932.1 CBZ38927.1 - 0.24 11.6 5.2 0.41 10.9 1.3 2.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain UPF0242 PF06785.11 CBZ38927.1 - 0.29 11.2 4.0 0.39 10.8 4.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 CBZ38927.1 - 0.69 10.6 6.9 2 9.1 1.9 2.2 1 1 0 2 2 2 0 Initiation control protein YabA DUF3450 PF11932.8 CBZ38927.1 - 0.95 8.7 8.2 0.29 10.4 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 CBZ38927.1 - 1.3 7.8 8.5 1.7 7.5 8.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein XhlA PF10779.9 CBZ38927.1 - 1.4 9.2 4.6 0.79 10.0 0.5 2.3 2 1 0 2 2 2 0 Haemolysin XhlA CCDC-167 PF15188.6 CBZ38927.1 - 1.6 9.1 10.4 4.4 7.7 0.8 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 kleA_kleC PF17383.2 CBZ38927.1 - 1.7 9.0 10.7 0.93 9.9 3.0 2.3 1 1 1 2 2 2 0 Uncharacterized KorC regulated protein A TSC22 PF01166.18 CBZ38927.1 - 3.7 7.9 7.6 2.1 8.7 0.5 2.8 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_2 PF07716.15 CBZ38927.1 - 5.2 7.2 13.0 3.7 7.7 0.4 3.2 2 1 2 4 4 4 0 Basic region leucine zipper DUF724 PF05266.14 CBZ38927.1 - 8.4 6.2 8.4 91 2.8 8.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF4140 PF13600.6 CBZ38927.1 - 8.8 6.8 8.8 4.7 7.7 1.6 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cyt-b5 PF00173.28 CBZ38928.1 - 1.1e-13 51.1 0.0 1.3e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Abhydrolase_1 PF00561.20 CBZ38930.1 - 0.0046 16.6 0.1 2.7 7.6 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold End_tail_spike PF12219.8 CBZ38930.1 - 0.12 12.4 0.9 0.32 11.0 0.2 2.0 2 0 0 2 2 2 0 Catalytic domain of bacteriophage endosialidase WD40 PF00400.32 CBZ38931.1 - 1.5e-10 41.4 4.4 0.062 14.2 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ38931.1 - 1.9e-07 31.3 0.0 0.99 9.8 0.0 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Flavodoxin_1 PF00258.25 CBZ38932.1 - 6.7e-34 117.1 0.0 3.2e-24 85.8 0.0 4.4 5 0 0 5 5 5 3 Flavodoxin FAD_binding_1 PF00667.20 CBZ38932.1 - 4.7e-18 65.6 0.0 8.5e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CBZ38932.1 - 1.1e-09 38.9 0.0 3.4e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain RabGAP-TBC PF00566.18 CBZ38933.1 - 0.033 13.8 0.2 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 Rab-GTPase-TBC domain PIG-P PF08510.12 CBZ38935.1 - 9.3e-28 96.6 1.5 1.1e-27 96.4 1.5 1.0 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 CBZ38935.1 - 0.036 14.4 8.7 0.099 13.0 8.7 1.7 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF2347 PF09804.9 CBZ38936.1 - 0.0035 17.0 0.1 0.044 13.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) LOB PF03195.14 CBZ38936.1 - 0.058 14.0 0.6 23 5.6 0.0 3.6 3 0 0 3 3 3 0 Lateral organ boundaries (LOB) domain Peptidase_M35 PF02102.15 CBZ38936.1 - 0.1 11.5 1.8 0.16 10.8 1.8 1.2 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family FAST_1 PF06743.15 CBZ38937.1 - 0.0014 18.6 0.4 16 5.5 0.1 5.4 5 1 1 6 6 6 3 FAST kinase-like protein, subdomain 1 DUF1749 PF08538.10 CBZ38938.1 - 2.9e-15 56.1 0.0 3.9e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 CBZ38938.1 - 0.024 13.9 0.4 0.04 13.2 0.4 1.5 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF4519 PF15012.6 CBZ38939.1 - 2.6 8.3 4.7 5.1 7.4 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) CAMSAP_CC1 PF17095.5 CBZ38939.1 - 3.9 7.4 11.4 0.12 12.2 0.5 3.3 3 0 0 3 3 3 0 Spectrin-binding region of Ca2+-Calmodulin Methyltransf_24 PF13578.6 CBZ38940.1 - 0.0062 17.5 0.1 0.024 15.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 CBZ38940.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PPR_2 PF13041.6 CBZ38941.1 - 4.6e-39 132.4 6.1 3.8e-16 59.0 0.8 5.1 3 1 2 5 5 5 5 PPR repeat family PPR_3 PF13812.6 CBZ38941.1 - 1.6e-34 117.8 0.4 8.4e-14 51.4 0.2 5.1 2 1 3 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.20 CBZ38941.1 - 4.2e-34 114.4 1.9 4.5e-06 26.6 0.0 6.2 6 0 0 6 6 6 5 PPR repeat PPR_1 PF12854.7 CBZ38941.1 - 2.4e-28 97.5 0.7 4.5e-09 35.9 0.0 6.2 6 0 0 6 6 6 5 PPR repeat PPR_long PF17177.4 CBZ38941.1 - 3.7e-21 75.5 0.3 3.9e-15 55.8 0.1 2.2 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 CBZ38941.1 - 1.9e-06 28.2 2.7 11 7.2 0.3 5.6 5 1 2 7 7 7 2 Tetratricopeptide repeat ATP13 PF12921.7 CBZ38941.1 - 0.017 15.0 0.0 13 5.7 0.0 3.5 2 1 1 4 4 4 0 Mitochondrial ATPase expression BTAD PF03704.17 CBZ38941.1 - 3 8.3 5.5 23 5.4 0.5 3.7 3 2 1 4 4 4 0 Bacterial transcriptional activator domain WD40 PF00400.32 CBZ38942.1 - 7.5e-37 124.7 12.5 3.7e-06 27.6 0.1 7.8 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CBZ38942.1 - 7.8e-07 29.3 0.1 1.2 9.5 0.0 5.3 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CBZ38942.1 - 0.0017 17.7 0.0 0.026 13.9 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain Roc PF08477.13 CBZ38943.1 - 3.5e-05 24.0 0.0 0.0044 17.2 0.0 2.7 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CBZ38943.1 - 0.0031 17.9 0.0 0.011 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.22 CBZ38943.1 - 0.03 13.9 0.0 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 Ras family SRPRB PF09439.10 CBZ38943.1 - 0.08 12.4 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CBZ38943.1 - 0.092 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase LRR_4 PF12799.7 CBZ38944.1 - 2.1e-28 97.9 37.7 0.00011 22.4 0.2 13.8 9 3 5 16 16 16 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ38944.1 - 3.7e-16 58.6 25.7 2.4e-05 24.0 1.2 7.9 7 2 0 7 7 7 5 Leucine rich repeat LRR_6 PF13516.6 CBZ38944.1 - 0.00051 19.9 39.3 0.0068 16.4 0.3 11.7 16 0 0 16 16 16 3 Leucine Rich repeat Spc29 PF17082.5 CBZ38945.1 - 0.13 12.1 0.3 0.26 11.1 0.3 1.5 1 0 0 1 1 1 0 Spindle Pole Component 29 PspB PF06667.12 CBZ38945.1 - 0.78 9.8 3.5 23 5.1 0.1 3.0 2 0 0 2 2 2 0 Phage shock protein B 2_5_RNA_ligase2 PF13563.6 CBZ38946.1 - 0.00068 19.6 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily MtN3_slv PF03083.16 CBZ38947.1 - 7.7e-25 86.7 19.9 5.9e-14 51.9 0.8 3.0 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange UNC-93 PF05978.16 CBZ38947.1 - 0.0046 16.7 1.4 0.0046 16.7 1.4 1.9 1 1 0 1 1 1 1 Ion channel regulatory protein UNC-93 LRR_4 PF12799.7 CBZ38948.1 - 8.7e-13 48.2 6.7 0.00038 20.8 0.1 4.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CBZ38948.1 - 5.3e-12 45.6 0.0 4.7e-09 36.0 0.2 2.3 1 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 CBZ38948.1 - 1.4e-09 37.6 12.3 1.4e-06 28.0 1.2 3.5 3 2 1 4 4 4 3 Leucine rich repeat Cuticle_4 PF15955.5 CBZ38948.1 - 0.041 14.6 0.2 0.065 13.9 0.2 1.4 1 0 0 1 1 1 0 Cuticle protein LRR_6 PF13516.6 CBZ38948.1 - 0.097 12.8 0.2 0.097 12.8 0.2 4.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 CBZ38948.1 - 0.16 12.7 7.1 19 6.3 0.1 5.2 4 1 0 4 4 4 0 Leucine Rich Repeat RNase_PH PF01138.21 CBZ38949.1 - 6.2e-14 52.6 0.3 1e-13 51.9 0.3 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Clathrin PF00637.20 CBZ38950.1 - 3.8e-07 30.1 1.1 1.5e-06 28.1 0.2 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 CBZ38950.1 - 0.0032 17.3 0.4 0.0093 15.8 0.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CBZ38950.1 - 0.015 15.6 0.4 0.015 15.6 0.4 2.3 2 0 0 2 2 2 0 Ring finger domain Vps8 PF12816.7 CBZ38950.1 - 0.028 13.9 0.1 22 4.5 0.0 4.1 5 0 0 5 5 5 0 Golgi CORVET complex core vacuolar protein 8 zf-rbx1 PF12678.7 CBZ38950.1 - 0.055 13.8 5.2 0.13 12.5 5.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CBZ38950.1 - 7.1 6.7 7.9 0.12 12.4 0.6 1.8 2 0 0 2 2 2 0 zinc-RING finger domain Nucleoplasmin PF03066.15 CBZ38951.1 - 0.89 10.1 6.7 0.32 11.5 3.2 2.1 1 1 1 2 2 2 0 Nucleoplasmin/nucleophosmin domain CH PF00307.31 CBZ38952.1 - 8.9e-12 45.2 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain RE_HindIII PF09518.10 CBZ38952.1 - 0.16 11.2 0.3 0.24 10.6 0.3 1.2 1 0 0 1 1 1 0 HindIII restriction endonuclease IF-2B PF01008.17 CBZ38953.1 - 7.6e-72 241.9 0.3 8.9e-72 241.7 0.3 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family UPF0029 PF01205.19 CBZ38954.1 - 1.6e-29 102.3 0.4 2.9e-29 101.5 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CBZ38954.1 - 0.00028 21.2 0.3 0.0033 17.7 0.3 2.3 1 1 0 1 1 1 1 RWD domain 2OG-FeII_Oxy_2 PF13532.6 CBZ38955.1 - 5.6e-07 29.9 0.0 3.4e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LPP PF04728.13 CBZ38955.1 - 1.2 9.5 3.1 1.6 9.2 1.1 2.1 2 0 0 2 2 2 0 Lipoprotein leucine-zipper START PF01852.19 CBZ38956.1 - 0.00036 20.0 0.0 1.9 7.8 0.0 3.1 3 0 0 3 3 3 3 START domain DnaJ PF00226.31 CBZ38957.1 - 2.1e-05 24.5 0.0 7.7e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 DnaJ domain HTH_38 PF13936.6 CBZ38957.1 - 0.03 14.1 0.0 0.086 12.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain PSP1 PF04468.12 CBZ38958.1 - 0.11 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 PSP1 C-terminal conserved region Tubulin PF00091.25 CBZ38959.1 - 2.4e-33 116.0 0.1 3.1e-24 86.3 0.0 2.9 2 1 1 3 3 3 2 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 CBZ38959.1 - 0.00082 18.7 0.1 0.0017 17.6 0.0 1.5 2 0 0 2 2 2 1 Tubulin like Ribosomal_S2 PF00318.20 CBZ38961.1 - 4.5e-08 32.6 0.0 5.1e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 Sulfotransfer_1 PF00685.27 CBZ38961.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Sulfotransferase domain DUF3113 PF11310.8 CBZ38962.1 - 0.083 12.8 1.3 3.7 7.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3113) SMAP PF15477.6 CBZ38962.1 - 7.1 7.7 0.0 7.1 7.7 0.0 5.9 6 3 0 6 6 6 0 Small acidic protein family MAP65_ASE1 PF03999.12 CBZ38963.1 - 0.037 12.8 10.6 0.0058 15.4 5.0 2.0 1 1 1 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) GIT_CC PF16559.5 CBZ38963.1 - 0.15 12.0 8.5 1.5 8.7 0.1 4.5 4 2 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-C4H2 PF10146.9 CBZ38963.1 - 0.34 11.2 17.9 1.3 9.2 0.9 2.6 1 1 2 3 3 2 0 Zinc finger-containing protein DUF948 PF06103.11 CBZ38963.1 - 0.38 11.0 6.7 3.5 7.9 0.4 3.8 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) HrpA_pilin PF09589.10 CBZ38963.1 - 0.89 10.3 5.5 2.3 9.0 5.1 1.9 1 1 0 1 1 1 0 HrpA pilus formation protein Gp-FAR-1 PF05823.12 CBZ38963.1 - 1 9.7 4.9 0.98 9.8 1.7 2.5 1 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1759 PF03564.15 CBZ38963.1 - 1.1 9.2 4.1 9.6 6.1 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) PE PF00934.20 CBZ38963.1 - 1.6 9.1 12.1 1.1 9.6 0.2 3.4 2 1 1 3 3 3 0 PE family GAS PF13851.6 CBZ38963.1 - 2 7.7 21.5 0.32 10.3 3.9 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF4446 PF14584.6 CBZ38963.1 - 2.2 8.3 9.1 17 5.4 0.3 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4446) DUF724 PF05266.14 CBZ38963.1 - 3.8 7.3 20.0 3 7.6 2.2 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.12 CBZ38963.1 - 4.1 7.4 9.3 14 5.7 2.3 3.7 2 1 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF445 PF04286.12 CBZ38963.1 - 5.1 6.8 12.3 10 5.8 11.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF445) SKA2 PF16740.5 CBZ38963.1 - 6 6.7 23.3 8.4 6.2 5.8 3.9 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 ADIP PF11559.8 CBZ38963.1 - 9.9 6.2 22.9 40 4.3 0.2 3.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Hexapep PF00132.24 CBZ38964.1 - 4.8e-09 35.6 11.2 0.035 13.8 0.2 5.0 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NOB1_Zn_bind PF08772.11 CBZ38966.1 - 6.9e-26 90.2 0.2 1.4e-25 89.2 0.2 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 CBZ38966.1 - 2.4e-22 79.2 0.2 4.4e-22 78.4 0.2 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease DUF35_N PF12172.8 CBZ38966.1 - 0.00023 20.9 0.8 0.00044 20.1 0.8 1.4 1 0 0 1 1 1 1 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.7 CBZ38966.1 - 0.01 15.8 0.3 0.018 15.1 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon SUV3_C PF12513.8 CBZ38967.1 - 0.11 12.4 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal Peripla_BP_4 PF13407.6 CBZ38968.1 - 0.011 15.4 0.1 0.08 12.5 0.1 2.1 2 0 0 2 2 2 0 Periplasmic binding protein domain DUF2316 PF10078.9 CBZ38968.1 - 0.17 12.1 0.3 1.1 9.5 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) CK_II_beta PF01214.18 CBZ38969.1 - 6.7e-74 247.6 0.0 8.1e-74 247.4 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HU-CCDC81_euk_2 PF18289.1 CBZ38971.1 - 2.1e-16 59.8 0.0 4.1e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 CBZ38971.1 - 3.6e-13 49.5 0.0 5.5e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 40S_SA_C PF16122.5 CBZ38972.1 - 0.0047 18.3 2.9 0.0072 17.7 2.9 1.3 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Porin_3 PF01459.22 CBZ38973.1 - 0.0049 16.4 0.4 0.22 11.0 0.1 2.7 2 1 0 2 2 2 2 Eukaryotic porin VHS PF00790.19 CBZ38974.1 - 2.3e-11 43.7 0.1 3.3e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 VHS domain Kinesin PF00225.23 CBZ38975.1 - 1.2e-23 83.6 0.0 3.5e-17 62.3 0.0 3.8 4 1 0 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 CBZ38975.1 - 1e-06 28.7 4.0 2e-06 27.8 0.0 3.4 3 1 0 3 3 3 1 Microtubule binding MA3 PF02847.17 CBZ38976.1 - 6.9e-13 48.6 1.2 6.9e-13 48.6 1.2 2.1 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 CBZ38976.1 - 3.9e-06 26.7 2.8 5.1e-06 26.3 0.2 2.2 2 1 0 2 2 2 1 MIF4G domain VPS28 PF03997.12 CBZ38977.1 - 1e-42 146.0 0.0 1.2e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Phage_Mu_Gam PF07352.12 CBZ38977.1 - 0.17 11.8 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Aldedh PF00171.22 CBZ38978.1 - 2.3e-130 435.2 1.1 2.5e-130 435.1 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNF2_N PF00176.23 CBZ38979.1 - 2.6e-61 207.3 0.0 4.9e-61 206.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CBZ38979.1 - 4.1e-18 65.7 0.0 9.4e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CBZ38979.1 - 1.2e-08 35.1 0.0 2.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CBZ38979.1 - 0.0029 17.4 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CBZ38979.1 - 0.0062 15.8 0.2 0.03 13.5 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Sec8_exocyst PF04048.14 CBZ38979.1 - 0.055 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain AAA_22 PF13401.6 CBZ38979.1 - 0.19 12.0 0.3 1.2 9.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain PRKCSH PF07915.13 CBZ38981.1 - 0.034 15.2 1.0 0.1 13.6 1.0 1.8 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein NDUF_B12 PF08122.12 CBZ38982.1 - 0.019 15.0 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family TPR_17 PF13431.6 CBZ38982.1 - 0.025 14.9 0.6 15 6.3 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_65m PF03632.15 CBZ38983.1 - 2.5e-69 234.0 0.0 5.1e-69 233.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 CBZ38983.1 - 3.5e-26 92.3 0.2 7.4e-26 91.2 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 CBZ38983.1 - 7.2e-06 25.8 0.1 3.8e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain HAD_2 PF13419.6 CBZ38983.1 - 0.0042 17.2 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Adaptin_N PF01602.20 CBZ38985.1 - 3.9e-78 263.3 0.0 4.9e-78 263.0 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBZ38985.1 - 3.1e-14 53.3 0.4 7.6e-14 52.1 0.4 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ38985.1 - 2.7e-06 27.7 10.1 9.2e-05 22.8 3.4 4.3 2 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 CBZ38985.1 - 0.00042 20.3 8.2 0.79 10.1 0.2 4.5 4 0 0 4 4 4 3 HEAT repeat Exo_endo_phos PF03372.23 CBZ38986.1 - 3.3e-09 36.6 0.0 2.7e-07 30.3 0.0 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CBZ38986.1 - 0.059 13.2 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Arm PF00514.23 CBZ38987.1 - 0.045 13.8 1.6 5.7 7.1 0.5 3.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CBZ38987.1 - 0.058 13.9 10.7 1.1 9.9 1.4 5.9 3 2 1 4 4 4 0 HEAT-like repeat HEAT PF02985.22 CBZ38987.1 - 1.2 9.6 14.7 1.9 9.0 0.0 6.2 7 1 1 8 8 8 0 HEAT repeat HEAT_2 PF13646.6 CBZ38987.1 - 2.4 8.6 20.0 0.68 10.4 1.3 5.7 6 1 0 6 6 6 0 HEAT repeats DUF737 PF05300.11 CBZ38988.1 - 1.2 9.5 10.7 1.9 8.8 10.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) GST_C_2 PF13410.6 CBZ38991.1 - 1.1e-07 31.8 0.6 3.3e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CBZ38991.1 - 0.00031 20.9 0.0 0.00066 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CBZ38991.1 - 0.025 14.8 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SR-25 PF10500.9 CBZ38992.1 - 5.7 6.5 19.4 16 5.0 19.4 1.8 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.25 CBZ38994.1 - 9.9e-58 195.6 0.0 1.5e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ38994.1 - 3e-35 121.7 0.0 5.1e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ38994.1 - 1.3e-10 41.1 0.0 3.4e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CBZ38994.1 - 0.00052 20.0 1.5 0.11 12.4 0.1 3.6 3 1 1 4 4 4 1 Phosphotransferase enzyme family C1_2 PF03107.16 CBZ38994.1 - 0.0015 18.8 3.8 0.0015 18.8 3.8 2.1 2 0 0 2 2 2 1 C1 domain Kdo PF06293.14 CBZ38994.1 - 0.017 14.5 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CBZ38994.1 - 0.025 13.6 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 zf-piccolo PF05715.13 CBZ38994.1 - 0.092 12.9 5.3 0.2 11.9 5.3 1.6 1 0 0 1 1 1 0 Piccolo Zn-finger Haspin_kinase PF12330.8 CBZ38994.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain SF1-HH PF16275.5 CBZ38994.1 - 0.68 10.3 2.7 0.87 9.9 0.2 2.5 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain FYVE_2 PF02318.16 CBZ38994.1 - 2.4 8.4 9.9 0.28 11.4 5.1 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger zf-UDP PF14569.6 CBZ38994.1 - 9.2 6.5 10.5 4.3 7.5 6.5 2.4 3 0 0 3 3 3 0 Zinc-binding RING-finger Ubie_methyltran PF01209.18 CBZ38995.1 - 3.7e-113 376.6 0.0 4.3e-113 376.4 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CBZ38995.1 - 3.4e-16 59.7 0.0 1.5e-15 57.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CBZ38995.1 - 9.5e-16 58.2 0.0 1.9e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ38995.1 - 1.2e-09 38.1 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CBZ38995.1 - 5.6e-07 30.2 0.0 8.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ38995.1 - 3.1e-05 23.9 0.0 4.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CBZ38995.1 - 0.0016 18.3 0.0 0.049 13.5 0.0 2.3 2 1 0 2 2 2 1 Hypothetical methyltransferase WD40 PF00400.32 CBZ38996.1 - 0.57 11.1 4.3 8.9 7.4 0.0 3.8 4 1 0 4 4 4 0 WD domain, G-beta repeat Y_phosphatase PF00102.27 CBZ38997.1 - 1.3e-66 224.6 0.0 1.7e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CBZ38997.1 - 0.00028 20.9 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CBZ38997.1 - 0.0004 20.2 0.0 0.00097 19.0 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CBZ38997.1 - 0.028 14.5 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Pyr_redox_2 PF07992.14 CBZ38998.1 - 8.8e-53 179.4 0.0 1.1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ38998.1 - 2.1e-10 41.0 0.0 1.8e-07 31.6 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CBZ38998.1 - 1.2e-05 24.6 0.0 0.0063 15.6 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 CBZ38998.1 - 0.00032 20.9 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CBZ38998.1 - 0.0027 17.4 0.3 1 8.9 0.0 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 CBZ38998.1 - 0.012 14.7 0.4 1.7 7.7 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CBZ38998.1 - 0.033 13.2 0.1 5.3 6.0 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CBZ38998.1 - 0.041 13.2 0.0 2.4 7.3 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pribosyltran_N PF13793.6 CBZ38999.1 - 1.7e-39 134.3 0.2 4.2e-39 133.1 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CBZ38999.1 - 2.4e-29 102.7 3.3 6e-29 101.4 1.2 2.2 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CBZ38999.1 - 5.7e-16 58.4 0.3 1.3e-15 57.3 0.3 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CBZ38999.1 - 0.00011 21.7 0.3 0.00026 20.5 0.1 1.7 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase IL2 PF00715.17 CBZ38999.1 - 0.099 12.6 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Interleukin 2 BCS1_N PF08740.11 CBZ39000.1 - 1.7e-29 103.2 2.2 2.7e-29 102.5 2.2 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CBZ39000.1 - 7.3e-11 42.6 0.0 3.8e-05 24.1 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CBZ39000.1 - 0.00029 20.6 0.0 0.00055 19.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CBZ39000.1 - 0.0004 20.8 0.5 0.0024 18.2 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CBZ39000.1 - 0.0024 17.8 0.0 0.0057 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CBZ39000.1 - 0.003 17.7 0.1 0.0097 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CBZ39000.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 CBZ39000.1 - 0.028 13.6 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 CBZ39000.1 - 0.067 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_3 PF07726.11 CBZ39000.1 - 0.16 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 CBZ39000.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_28 PF13521.6 CBZ39000.1 - 0.18 12.0 0.6 1.2 9.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CBZ39000.1 - 0.18 12.3 0.0 0.46 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AIRS_C PF02769.22 CBZ39001.1 - 2.4e-17 63.5 0.0 5.4e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 CBZ39001.1 - 8.7e-09 35.9 0.6 2e-08 34.7 0.1 1.8 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Extensin-like_C PF06904.12 CBZ39001.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Extensin-like protein C-terminus SF1-HH PF16275.5 CBZ39002.1 - 6.5e-07 29.7 0.1 1.5e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CBZ39002.1 - 5e-06 26.3 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 KH domain DUF3824 PF12868.7 CBZ39002.1 - 0.13 12.9 7.5 0.29 11.8 7.5 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ribosomal_60s PF00428.19 CBZ39002.1 - 8.2 7.1 14.4 23 5.7 14.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein TylF PF05711.11 CBZ39003.1 - 2.9e-20 72.6 0.0 2.1e-19 69.8 0.0 2.1 1 1 0 1 1 1 1 Macrocin-O-methyltransferase (TylF) Methyltransf_24 PF13578.6 CBZ39003.1 - 5.6e-08 33.8 0.1 5.2e-07 30.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain CmcI PF04989.12 CBZ39003.1 - 0.04 13.6 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Cephalosporin hydroxylase SEP PF08059.13 CBZ39004.1 - 2.2e-08 34.6 0.0 6.4e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CBZ39004.1 - 0.00013 22.1 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain FPP PF05911.11 CBZ39004.1 - 0.00032 19.1 4.3 0.00046 18.5 4.3 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 CBZ39004.1 - 0.0022 18.2 8.6 0.0037 17.5 5.4 2.2 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Jnk-SapK_ap_N PF09744.9 CBZ39004.1 - 0.012 15.9 5.0 0.012 15.9 5.0 1.6 2 0 0 2 2 1 0 JNK_SAPK-associated protein-1 CALCOCO1 PF07888.11 CBZ39004.1 - 0.012 14.5 4.3 0.02 13.8 4.3 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Golgin_A5 PF09787.9 CBZ39004.1 - 0.051 13.0 4.0 0.098 12.1 4.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 APG6_N PF17675.1 CBZ39004.1 - 0.066 13.7 11.9 0.1 13.1 10.4 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region tRNA-synt_1d PF00750.19 CBZ39004.1 - 0.071 12.1 1.5 0.11 11.5 1.5 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) Cep57_MT_bd PF06657.13 CBZ39004.1 - 0.11 13.0 6.2 0.19 12.2 5.2 1.9 1 1 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Fmp27_WPPW PF10359.9 CBZ39004.1 - 0.14 11.0 0.5 0.23 10.3 0.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Filament PF00038.21 CBZ39004.1 - 0.3 10.6 9.6 0.025 14.1 4.5 1.7 2 0 0 2 2 2 0 Intermediate filament protein FapA PF03961.13 CBZ39004.1 - 0.3 9.6 1.1 0.48 9.0 1.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 CBZ39004.1 - 0.64 9.3 7.8 0.06 12.7 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 CBZ39004.1 - 0.77 10.0 8.2 0.14 12.4 4.4 1.7 2 0 0 2 2 1 0 Spc24 subunit of Ndc80 OmpH PF03938.14 CBZ39004.1 - 3.5 8.0 12.4 0.25 11.7 6.4 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.12 CBZ39004.1 - 3.6 7.6 17.3 0.17 11.9 9.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 CBZ39004.1 - 6.9 6.9 12.2 5.1 7.3 7.6 2.4 2 1 0 2 2 1 0 TATA element modulatory factor 1 TATA binding DAO PF01266.24 CBZ39006.1 - 7.5e-45 154.0 0.0 9.5e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ39006.1 - 0.00066 19.8 0.1 0.0016 18.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBZ39006.1 - 0.00097 18.5 0.5 0.0029 16.9 0.4 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CBZ39006.1 - 0.0047 16.2 0.5 0.2 10.9 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CBZ39006.1 - 0.0058 15.9 0.2 0.024 13.9 0.0 2.0 3 0 0 3 3 3 1 Thi4 family Mqo PF06039.15 CBZ39006.1 - 0.0094 14.5 0.0 0.042 12.4 0.0 1.9 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) TrkA_N PF02254.18 CBZ39006.1 - 0.01 16.1 0.1 0.039 14.2 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.27 CBZ39006.1 - 0.078 13.5 0.1 0.2 12.2 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CBZ39006.1 - 0.11 11.6 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DUF5641 PF18701.1 CBZ39007.1 - 0.056 13.6 0.2 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5641) US6 PF17616.2 CBZ39007.1 - 0.078 12.9 0.5 0.22 11.5 0.5 1.7 1 0 0 1 1 1 0 Viral unique short region 6 ApoC-I PF04691.12 CBZ39009.1 - 0.075 13.0 0.0 0.61 10.0 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) HlyIII PF03006.20 CBZ39010.1 - 3.6e-51 174.0 23.7 4.8e-51 173.6 23.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.20 CBZ39011.1 - 1.1e-48 165.9 26.0 1.4e-48 165.5 26.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.20 CBZ39012.1 - 5.3e-54 183.3 27.1 6.8e-54 182.9 27.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related PCIF1_WW PF12237.8 CBZ39013.1 - 8.1e-28 97.2 0.1 5.2e-18 65.3 0.2 2.3 2 0 0 2 2 2 2 Phosphorylated CTD interacting factor 1 WW domain KTI12 PF08433.10 CBZ39014.1 - 0.004 16.7 0.6 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_33 PF13671.6 CBZ39014.1 - 0.031 14.4 0.4 0.031 14.4 0.4 2.9 2 2 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CBZ39014.1 - 0.048 14.0 0.0 0.048 14.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Peptidase_M24 PF00557.24 CBZ39016.1 - 2.3e-34 118.9 0.0 3.8e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CBZ39016.1 - 3.1e-09 36.6 0.0 1.2e-08 34.7 0.0 2.1 3 0 0 3 3 3 1 Aminopeptidase P, N-terminal domain Pox_F17 PF04767.12 CBZ39016.1 - 0.16 12.5 3.5 0.13 12.7 0.4 2.5 2 0 0 2 2 2 0 DNA-binding 11 kDa phosphoprotein EMP24_GP25L PF01105.24 CBZ39017.1 - 7.5e-11 42.3 0.0 9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HrpB2 PF09487.10 CBZ39018.1 - 0.00053 20.4 0.0 0.0021 18.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB2) NICE-3 PF07406.11 CBZ39018.1 - 0.081 12.9 0.0 1.2 9.1 0.1 2.1 2 0 0 2 2 2 0 NICE-3 protein CAP_C PF08603.11 CBZ39019.1 - 2.1e-47 160.7 3.4 2.8e-47 160.3 3.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal CAP_N PF01213.19 CBZ39019.1 - 4.6e-13 49.3 5.5 4.6e-13 49.3 5.5 1.6 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal TBCC PF07986.12 CBZ39019.1 - 9.3e-06 25.4 7.4 1.6e-05 24.7 7.4 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C RskA PF10099.9 CBZ39019.1 - 0.0038 17.6 3.4 0.006 16.9 3.4 1.4 1 0 0 1 1 1 1 Anti-sigma-K factor rskA XRCC1_N PF01834.16 CBZ39019.1 - 0.075 13.0 0.6 0.28 11.2 0.2 2.0 1 1 1 2 2 2 0 XRCC1 N terminal domain Sde2_N_Ubi PF13019.6 CBZ39019.1 - 0.72 9.7 2.8 20 4.9 0.0 2.2 2 0 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain DUF573 PF04504.14 CBZ39021.1 - 0.054 14.2 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF573 tRNA-synt_1 PF00133.22 CBZ39023.1 - 1.2e-213 710.8 3.7 3.7e-213 709.1 0.2 2.8 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CBZ39023.1 - 9.7e-21 74.3 0.0 3.1e-20 72.7 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CBZ39023.1 - 3.1e-13 49.2 2.5 0.00076 18.3 0.3 3.9 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CBZ39023.1 - 0.0025 17.2 1.2 0.089 12.1 0.0 3.1 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain SWIM PF04434.17 CBZ39024.1 - 0.24 11.1 2.7 0.48 10.1 2.7 1.5 1 0 0 1 1 1 0 SWIM zinc finger Cyclin_N PF00134.23 CBZ39025.1 - 0.00082 19.1 0.1 0.0065 16.2 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain DAO PF01266.24 CBZ39027.1 - 9.4e-18 64.9 2.6 1.1e-10 41.6 1.2 3.3 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CBZ39027.1 - 7.2e-08 32.6 0.6 3.2e-07 30.5 0.7 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CBZ39027.1 - 3.5e-06 26.5 0.1 6.8e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CBZ39027.1 - 1.6e-05 25.4 1.7 4.2e-05 24.0 1.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CBZ39027.1 - 0.00028 20.2 0.1 0.00061 19.1 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 CBZ39027.1 - 0.0018 17.4 0.7 0.0031 16.6 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CBZ39027.1 - 0.0027 16.8 0.8 0.0046 16.1 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 CBZ39027.1 - 0.022 14.6 0.7 0.052 13.4 0.7 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CBZ39027.1 - 0.023 14.0 0.4 0.043 13.1 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CBZ39027.1 - 0.03 13.0 0.5 0.046 12.4 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CBZ39027.1 - 0.033 13.4 0.1 0.076 12.3 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CBZ39027.1 - 0.072 13.1 0.3 0.18 11.8 0.3 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 CBZ39027.1 - 0.086 12.1 1.8 0.077 12.2 0.5 1.5 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 CBZ39027.1 - 0.26 10.6 1.7 0.88 8.8 1.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HA2 PF04408.23 CBZ39028.1 - 1.8e-15 57.1 0.2 4e-15 56.0 0.2 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CBZ39028.1 - 3.3e-15 56.2 0.0 8.1e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CBZ39028.1 - 1.7e-13 50.9 0.0 4.5e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CBZ39028.1 - 5.8e-10 39.2 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CBZ39028.1 - 0.00026 21.3 0.3 0.0011 19.3 0.1 2.1 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 CBZ39028.1 - 0.014 14.9 0.1 0.069 12.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 CBZ39028.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 CBZ39028.1 - 0.017 14.2 0.2 0.04 13.0 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ResIII PF04851.15 CBZ39028.1 - 0.024 14.6 0.0 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CBZ39028.1 - 0.027 14.8 0.5 0.089 13.1 0.0 2.1 2 2 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CBZ39028.1 - 0.039 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain CK2S PF15011.6 CBZ39028.1 - 0.043 13.7 0.1 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Casein Kinase 2 substrate Kringle PF00051.18 CBZ39028.1 - 0.062 13.6 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Kringle domain ATPase PF06745.13 CBZ39028.1 - 0.098 12.0 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 KaiC CUE PF02845.16 CBZ39031.1 - 0.043 13.5 0.3 0.66 9.7 0.0 2.6 2 0 0 2 2 2 0 CUE domain Cullin_binding PF03556.15 CBZ39032.1 - 2.9e-20 72.9 2.9 5.1e-20 72.1 2.9 1.4 1 0 0 1 1 1 1 Cullin binding DUF1685 PF07939.11 CBZ39034.1 - 0.034 13.9 0.0 5.8 6.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) TruD PF01142.18 CBZ39036.1 - 1.3e-59 202.1 0.0 7.8e-58 196.2 0.0 2.7 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) RAB3GAP2_N PF14655.6 CBZ39037.1 - 7e-12 45.3 0.1 1.1e-11 44.7 0.1 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus MS_channel PF00924.18 CBZ39038.1 - 2.9e-18 66.2 0.9 3.5e-18 65.9 0.9 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel Gcd10p PF04189.13 CBZ39039.1 - 4.6e-47 160.6 0.1 6e-47 160.2 0.1 1.2 1 0 0 1 1 1 1 Gcd10p family LRR_9 PF14580.6 CBZ39040.1 - 6.4e-05 22.5 0.0 0.00024 20.7 0.0 1.9 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CBZ39040.1 - 0.00023 21.5 0.3 0.0099 16.3 0.1 2.8 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CBZ39040.1 - 0.00099 18.8 0.0 0.047 13.5 0.0 2.5 1 1 2 3 3 3 1 Leucine rich repeat DUF383 PF04063.14 CBZ39041.1 - 0.0016 18.2 0.0 4.1 7.0 0.0 3.4 2 1 1 3 3 3 3 Domain of unknown function (DUF383) DUF945 PF06097.11 CBZ39042.1 - 0.0082 15.3 1.1 0.012 14.7 1.1 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF945) HECW1_helix PF18436.1 CBZ39042.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 GvpL_GvpF PF06386.11 CBZ39042.1 - 2.5 8.0 9.5 0.26 11.2 3.5 2.1 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DUF4404 PF14357.6 CBZ39042.1 - 2.6 8.7 9.5 2.7 8.7 3.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Nitroreductase PF00881.24 CBZ39044.1 - 2.9e-12 47.0 0.2 3.5e-12 46.7 0.2 1.1 1 0 0 1 1 1 1 Nitroreductase family BLIP PF07467.11 CBZ39044.1 - 0.055 14.1 0.3 0.087 13.4 0.3 1.2 1 0 0 1 1 1 0 Beta-lactamase inhibitor (BLIP) HMG_box PF00505.19 CBZ39045.1 - 0.046 14.1 1.4 1.1 9.7 0.0 3.1 3 1 0 3 3 3 0 HMG (high mobility group) box HMG_box_2 PF09011.10 CBZ39046.1 - 3.8e-05 24.2 2.8 0.026 15.1 0.2 2.4 2 1 0 2 2 2 2 HMG-box domain YABBY PF04690.13 CBZ39046.1 - 0.00024 21.7 0.7 0.00028 21.5 0.7 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.19 CBZ39046.1 - 0.13 12.7 4.5 0.26 11.7 0.4 2.9 2 2 0 2 2 2 0 HMG (high mobility group) box AAA PF00004.29 CBZ39048.1 - 1.9e-11 44.5 0.0 9.5e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ39048.1 - 3.7e-05 23.8 0.0 7.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CBZ39048.1 - 0.00041 20.8 3.2 0.0037 17.7 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CBZ39048.1 - 0.0019 17.4 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) HIP1_clath_bdg PF16515.5 CBZ39048.1 - 0.12 13.0 0.8 0.23 12.1 0.8 1.4 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_7 PF12775.7 CBZ39048.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 CBZ39050.1 - 2e-67 227.0 0.3 2.7e-67 226.5 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ39050.1 - 3.8e-07 30.2 0.0 1e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CBZ39050.1 - 6.7e-06 26.3 0.0 2.6e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ39050.1 - 9.6e-06 25.2 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CBZ39050.1 - 0.0085 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Ras family YliH PF10799.8 CBZ39050.1 - 0.0097 15.8 0.9 0.019 14.9 0.1 1.9 2 0 0 2 2 2 1 Biofilm formation protein (YliH/bssR) ATP_bind_1 PF03029.17 CBZ39050.1 - 0.011 15.5 0.5 0.022 14.6 0.2 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRPRB PF09439.10 CBZ39050.1 - 0.013 15.0 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF910 PF06014.11 CBZ39050.1 - 0.081 12.9 0.0 0.29 11.2 0.0 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) CDP-OH_P_transf PF01066.21 CBZ39052.1 - 1.2e-17 64.4 0.1 1.2e-17 64.4 0.1 4.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Lge1 PF11488.8 CBZ39054.1 - 0.03 14.5 0.1 0.03 14.5 0.1 1.9 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Taxilin PF09728.9 CBZ39055.1 - 1.8e-05 24.1 56.6 2.3e-05 23.8 56.6 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.8 CBZ39055.1 - 0.03 14.6 2.5 0.03 14.6 2.5 4.1 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 CBZ39055.1 - 2.9 8.4 17.3 5.3 7.6 0.1 4.3 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 CBZ39055.1 - 7.2 5.4 55.6 1.1 8.0 2.1 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein LmjF365940-deam PF14421.6 CBZ39056.1 - 1.5e-42 145.4 0.1 2.3e-22 79.6 0.1 2.3 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_1 PF00383.23 CBZ39056.1 - 0.13 12.2 0.1 0.25 11.2 0.1 1.5 1 1 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF5567 PF17722.1 CBZ39057.1 - 4.4e-06 26.7 0.1 0.17 11.8 0.0 3.1 2 1 1 3 3 3 3 Family of unknown function (DUF5567) DUF4996 PF16387.5 CBZ39058.1 - 3.2e-31 107.8 0.1 8e-31 106.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function GDPD PF03009.17 CBZ39058.1 - 3.6e-23 82.6 0.1 8.2e-23 81.5 0.1 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 CBZ39058.1 - 0.0093 15.6 0.1 0.022 14.4 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Tmemb_185A PF10269.9 CBZ39059.1 - 3.7e-06 26.8 3.8 0.011 15.4 0.0 2.4 2 0 0 2 2 2 2 Transmembrane Fragile-X-F protein DUF2207 PF09972.9 CBZ39059.1 - 0.013 14.3 5.7 1.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 CBZ39059.1 - 1.3 9.1 14.9 8 6.5 0.0 2.4 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III ICMT PF04140.14 CBZ39059.1 - 1.7 9.1 8.8 1.8 9.1 1.0 3.0 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family EphA2_TM PF14575.6 CBZ39059.1 - 2.7 8.9 0.0 2.7 8.9 0.0 3.3 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain RRM_1 PF00076.22 CBZ39060.1 - 0.016 15.0 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WW PF00397.26 CBZ39060.1 - 0.15 12.2 0.3 0.3 11.2 0.3 1.5 1 0 0 1 1 1 0 WW domain SpoV PF08183.11 CBZ39061.1 - 6.6e-07 29.2 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Stage V sporulation protein family Trimer_CC PF08954.11 CBZ39062.1 - 0.98 9.0 8.9 0.51 9.9 2.4 3.2 2 0 0 2 2 2 0 Trimerisation motif Osmo_CC PF08946.10 CBZ39062.1 - 1.7 8.9 4.6 20 5.5 0.2 3.1 2 0 0 2 2 2 0 Osmosensory transporter coiled coil TMF_DNA_bd PF12329.8 CBZ39063.1 - 0.0085 16.1 7.2 0.0085 16.1 7.2 3.8 4 0 0 4 4 4 2 TATA element modulatory factor 1 DNA binding AHSP PF09236.10 CBZ39063.1 - 0.045 14.2 0.3 0.14 12.6 0.3 1.8 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein Baculo_PEP_C PF04513.12 CBZ39063.1 - 0.065 13.3 4.3 0.71 9.9 0.4 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 CBZ39063.1 - 1.6 8.3 34.5 0.45 10.0 11.4 3.2 1 1 0 2 2 2 0 Intermediate filament protein TMF_TATA_bd PF12325.8 CBZ39063.1 - 5.9 7.1 29.5 0.26 11.5 4.2 3.8 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding OTU PF02338.19 CBZ39064.1 - 0.00012 22.6 0.0 0.00038 21.0 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease FAP206 PF12018.8 CBZ39065.1 - 7.6e-12 45.3 0.0 0.0002 21.0 0.0 4.9 4 0 0 4 4 4 3 Domain of unknown function YHS PF04945.13 CBZ39065.1 - 1.3e-06 28.4 1.6 0.055 13.6 0.4 4.2 4 0 0 4 4 4 2 YHS domain AAA_18 PF13238.6 CBZ39065.1 - 3.2e-05 24.5 0.1 0.034 14.7 0.0 3.6 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.6 CBZ39065.1 - 0.00012 22.5 2.0 0.035 14.5 0.0 4.1 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CBZ39065.1 - 0.00059 20.0 0.0 0.00059 20.0 0.0 4.1 3 1 0 4 4 4 1 AAA domain AAA PF00004.29 CBZ39065.1 - 0.01 16.3 0.0 0.2 12.1 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CBZ39065.1 - 0.012 15.6 0.0 0.52 10.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ADK PF00406.22 CBZ39065.1 - 0.018 15.1 0.1 0.087 12.9 0.0 2.2 3 0 0 3 3 3 0 Adenylate kinase Cytidylate_kin PF02224.18 CBZ39065.1 - 0.037 13.8 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_16 PF13191.6 CBZ39065.1 - 0.045 14.1 17.8 0.65 10.4 6.4 5.3 4 1 0 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 CBZ39065.1 - 0.16 12.2 0.0 1.7 8.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 CBZ39065.1 - 0.2 11.2 0.6 0.82 9.3 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SKI PF01202.22 CBZ39065.1 - 0.27 11.4 3.1 0.85 9.7 0.0 3.2 3 0 0 3 3 3 0 Shikimate kinase COG2 PF06148.11 CBZ39066.1 - 9.8e-45 151.9 0.0 2.6e-44 150.5 0.0 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 CBZ39066.1 - 3.4e-30 105.0 2.1 1.3e-29 103.1 0.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3510) MIF4G PF02854.19 CBZ39068.1 - 5.9e-22 78.4 0.0 1.5e-21 77.0 0.0 1.7 2 0 0 2 2 2 1 MIF4G domain RabGAP-TBC PF00566.18 CBZ39069.1 - 3.8e-58 196.7 0.0 4.7e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 CBZ39070.1 - 7.7e-60 202.2 0.3 1e-59 201.8 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ABC1 PF03109.16 CBZ39071.1 - 1.4e-28 99.5 0.0 3e-28 98.4 0.0 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 CBZ39071.1 - 2e-07 30.7 0.0 0.0052 16.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ39071.1 - 1.6e-06 27.6 0.1 0.0075 15.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CBZ39071.1 - 0.00017 21.6 0.0 0.00027 20.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CBZ39071.1 - 0.0005 19.7 0.0 0.00098 18.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family CagD PF16567.5 CBZ39071.1 - 0.047 13.5 0.7 0.089 12.6 0.2 1.6 2 0 0 2 2 2 0 Pathogenicity island component CagD CRISPR_Cas6 PF10040.9 CBZ39071.1 - 0.059 14.0 0.0 0.51 11.0 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated endoribonuclease Cas6 NanE PF04131.14 CBZ39071.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase UBM PF14377.6 CBZ39071.1 - 0.5 9.9 4.4 0.2 11.2 0.4 2.4 2 0 0 2 2 2 0 Ubiquitin binding region TPR_16 PF13432.6 CBZ39072.1 - 0.0018 18.9 26.0 2 9.2 1.9 5.6 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 CBZ39072.1 - 0.0024 18.3 14.9 1.7 9.2 2.5 5.2 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ39072.1 - 0.02 15.0 16.1 7.9 6.9 0.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 CBZ39072.1 - 0.039 14.8 18.9 2 9.4 0.2 5.6 4 2 2 6 6 6 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CBZ39072.1 - 0.07 12.8 4.1 0.28 10.8 0.0 3.6 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) ANAPC3 PF12895.7 CBZ39072.1 - 0.2 11.9 15.1 0.48 10.7 0.6 5.1 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CBZ39072.1 - 3.4 7.6 5.9 28 4.7 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 CBZ39072.1 - 7.4 6.8 10.1 2.5 8.4 0.5 4.6 5 0 0 5 5 5 0 HemY protein N-terminus EF-hand_7 PF13499.6 CBZ39073.1 - 1.9e-14 53.8 3.3 1.9e-06 28.2 0.0 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CBZ39073.1 - 5.8e-09 35.2 1.8 0.0022 17.8 0.0 4.2 4 1 1 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 CBZ39073.1 - 2.4e-08 33.7 0.5 0.0033 17.2 0.5 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CBZ39073.1 - 3.2e-08 32.5 2.1 0.012 15.1 0.0 4.6 4 1 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 CBZ39073.1 - 1.2e-05 25.6 0.1 0.002 18.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CBZ39073.1 - 0.034 13.7 0.3 3.1 7.5 0.1 3.3 3 0 0 3 3 3 0 EF hand ATP_bind_3 PF01171.20 CBZ39074.1 - 1e-16 61.3 0.0 1.8e-16 60.5 0.0 1.4 1 1 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CBZ39074.1 - 3.4e-11 42.5 5.3 3.4e-11 42.5 5.3 3.5 3 0 0 3 3 3 1 Zinc-ribbon tRNA_Me_trans PF03054.16 CBZ39074.1 - 0.043 12.6 0.0 0.092 11.5 0.0 1.5 1 1 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 CBZ39074.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.3 1 1 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family TF_Zn_Ribbon PF08271.12 CBZ39074.1 - 0.35 10.4 2.4 0.9 9.1 0.2 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding SUIM_assoc PF16619.5 CBZ39075.1 - 0.016 15.3 2.3 0.034 14.2 0.0 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 FAM76 PF16046.5 CBZ39075.1 - 0.2 10.9 4.5 0.052 12.9 1.2 1.6 2 0 0 2 2 2 0 FAM76 protein Fis1_TPR_C PF14853.6 CBZ39077.1 - 2.9e-05 24.0 1.5 6.5e-05 22.9 0.8 2.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.28 CBZ39077.1 - 0.003 17.3 0.1 0.0082 15.9 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CBZ39077.1 - 0.028 14.5 0.0 0.12 12.6 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Ran_BP1 PF00638.18 CBZ39078.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 RanBP1 domain Kelch_5 PF13854.6 CBZ39079.1 - 8.3e-15 54.4 1.7 0.016 15.2 0.0 5.7 7 0 0 7 7 7 4 Kelch motif Kelch_4 PF13418.6 CBZ39079.1 - 5.6e-12 45.5 2.6 0.0096 15.9 0.0 5.2 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CBZ39079.1 - 9.9e-11 41.7 8.4 0.053 13.8 0.0 5.8 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CBZ39079.1 - 1.4e-10 40.5 1.2 0.018 14.6 0.0 5.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 CBZ39079.1 - 1.6e-07 31.4 2.4 2 8.9 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 CBZ39079.1 - 1.8e-05 24.5 0.1 0.56 10.3 0.0 4.9 5 0 0 5 5 5 1 Kelch motif Suc_Fer-like PF06999.12 CBZ39080.1 - 4.1e-27 95.3 0.1 6.2e-27 94.7 0.1 1.3 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Vps54 PF07928.12 CBZ39083.1 - 4.8e-22 78.8 0.2 8.6e-21 74.8 0.1 3.0 2 1 0 2 2 2 1 Vps54-like protein GCN5L1 PF06320.13 CBZ39083.1 - 0.0041 17.2 0.0 0.032 14.4 0.0 2.4 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) COG2 PF06148.11 CBZ39083.1 - 0.053 13.6 0.0 0.21 11.7 0.0 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.7 CBZ39084.1 - 0.019 15.1 1.0 0.019 15.1 1.0 3.2 3 0 0 3 3 3 0 Tropomyosin like AAA_13 PF13166.6 CBZ39084.1 - 3.4 6.2 10.9 5.7 5.4 10.9 1.2 1 0 0 1 1 1 0 AAA domain FAM76 PF16046.5 CBZ39084.1 - 5.5 6.3 14.3 0.52 9.6 0.3 2.6 1 1 1 2 2 2 0 FAM76 protein Arf PF00025.21 CBZ39085.1 - 1.2e-60 203.9 0.0 1.3e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CBZ39085.1 - 6.8e-13 48.9 0.0 9.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CBZ39085.1 - 2.9e-12 46.4 0.0 1.5e-09 37.5 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CBZ39085.1 - 1.3e-11 44.3 0.0 1.6e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CBZ39085.1 - 1.7e-11 43.9 0.0 2.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CBZ39085.1 - 2e-10 40.8 0.0 3.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CBZ39085.1 - 9e-10 38.3 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CBZ39085.1 - 0.0011 18.5 0.0 0.0029 17.2 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 CBZ39085.1 - 0.0069 15.4 0.1 0.095 11.7 0.1 2.2 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 CBZ39085.1 - 0.011 15.3 0.1 0.12 11.9 0.1 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 CBZ39085.1 - 0.014 14.8 0.0 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein DSBA PF01323.20 CBZ39085.1 - 0.041 13.7 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain AAA_18 PF13238.6 CBZ39085.1 - 0.044 14.3 0.0 0.086 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CBZ39085.1 - 0.059 13.8 0.0 0.086 13.2 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 CBZ39085.1 - 0.06 13.1 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 CBZ39085.1 - 0.06 13.3 0.0 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase CdhD PF03599.16 CBZ39085.1 - 0.068 11.9 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Thioredoxin_2 PF13098.6 CBZ39085.1 - 0.073 13.5 0.0 0.098 13.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain cobW PF02492.19 CBZ39085.1 - 0.1 12.2 0.1 0.77 9.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.23 CBZ39085.1 - 0.11 12.5 0.0 9.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.6 CBZ39086.1 - 0.021 15.0 0.1 0.054 13.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CBZ39086.1 - 0.2 11.7 0.0 0.55 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CBZ39086.1 - 0.2 11.9 0.0 0.44 10.8 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CBZ39087.1 - 4.4e-47 159.7 1.8 1e-46 158.5 0.7 1.9 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CBZ39087.1 - 7.7e-31 106.8 0.9 2e-30 105.5 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CBZ39087.1 - 3e-06 26.8 0.0 3.9e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CBZ39087.1 - 0.0039 17.3 0.1 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CBZ39087.1 - 0.0098 15.4 0.0 3.7 7.1 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CBZ39087.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TniB PF05621.11 CBZ39087.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Peptidase_M32 PF02074.15 CBZ39088.1 - 2.3e-90 303.7 0.0 2.7e-90 303.5 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase DnaJ_C PF01556.18 CBZ39089.1 - 4e-36 124.3 0.0 5.3e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CBZ39089.1 - 6.5e-27 93.4 5.2 1.1e-26 92.8 5.2 1.3 1 0 0 1 1 1 1 DnaJ domain DUF643 PF04867.12 CBZ39089.1 - 0.052 14.2 0.2 0.51 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF643) Sugar_tr PF00083.24 CBZ39090.1 - 2.3e-30 105.9 3.2 2.6e-30 105.7 3.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CBZ39090.1 - 0.00069 18.6 0.1 0.00089 18.3 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CBZ39091.1 - 1.4e-96 324.2 36.1 1e-57 196.1 16.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CBZ39091.1 - 7.2e-15 54.8 37.0 1.8e-13 50.1 35.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily S-methyl_trans PF02574.16 CBZ39092.1 - 1.1e-69 235.3 0.0 1.3e-69 235.0 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.25 CBZ39092.1 - 0.0068 16.0 1.1 0.011 15.3 0.1 1.8 2 0 0 2 2 2 1 Kelch motif FliG_M PF14841.6 CBZ39092.1 - 0.076 13.2 0.3 10 6.4 0.2 2.5 2 0 0 2 2 2 0 FliG middle domain HEPN_SAV_6107 PF18726.1 CBZ39092.1 - 0.18 12.3 3.1 0.18 12.4 0.5 2.3 2 0 0 2 2 2 0 SAV_6107-like HEPN PI3_PI4_kinase PF00454.27 CBZ39093.1 - 5.1e-63 213.2 0.0 9.4e-63 212.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CBZ39093.1 - 8.7e-54 183.0 0.3 2e-53 181.8 0.3 1.6 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.8 CBZ39093.1 - 1.5e-21 77.0 2.9 8.6e-20 71.3 0.0 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CBZ39093.1 - 2e-21 76.3 0.1 9.8e-21 74.0 0.1 2.4 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 CBZ39093.1 - 5.4e-16 58.1 0.2 1.3e-15 56.9 0.2 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 CBZ39093.1 - 3.6e-07 30.5 6.0 0.25 11.7 0.1 6.7 6 0 0 6 6 6 3 HEAT repeats IFRD PF05004.13 CBZ39093.1 - 0.027 13.6 0.0 1.7 7.7 0.0 2.6 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 CBZ39093.1 - 0.37 11.2 11.1 24 5.6 0.1 7.5 6 0 0 6 6 6 0 HEAT repeat UTP15_C PF09384.10 CBZ39094.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 UTP15 C terminal TB2_DP1_HVA22 PF03134.19 CBZ39094.1 - 1.1 9.2 5.0 1.4 8.9 0.2 2.6 3 0 0 3 3 3 0 TB2/DP1, HVA22 family HECT PF00632.25 CBZ39095.1 - 1.2e-53 182.6 0.0 1.9e-53 182.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CBZ39095.1 - 3.6e-39 133.6 0.0 2.6e-16 59.8 0.0 4.3 4 0 0 4 4 4 3 SPRY domain Laminin_G_3 PF13385.6 CBZ39095.1 - 8.5e-16 58.5 0.0 7.5e-08 32.7 0.0 4.1 4 0 0 4 4 4 2 Concanavalin A-like lectin/glucanases superfamily Pox_MCEL PF03291.16 CBZ39096.1 - 0.022 13.9 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme PH_11 PF15413.6 CBZ39097.1 - 0.0079 16.6 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Syntaxin-6_N PF09177.11 CBZ39097.1 - 0.14 12.8 0.7 0.31 11.6 0.1 2.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal CAF1 PF04857.20 CBZ39098.1 - 1.1e-64 218.6 0.0 1.4e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DUF3371 PF11851.8 CBZ39098.1 - 0.082 14.0 0.1 0.58 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) Tma16 PF11176.8 CBZ39099.1 - 2.6e-23 82.5 0.2 2.6e-23 82.5 0.2 1.6 2 0 0 2 2 2 1 Translation machinery-associated protein 16 RabGAP-TBC PF00566.18 CBZ39100.1 - 1.3e-13 51.1 0.9 1.9e-13 50.6 0.9 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ArfGap PF01412.18 CBZ39100.1 - 0.099 12.7 0.2 0.28 11.3 0.2 1.7 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DUF1126 PF06565.12 CBZ39101.1 - 4.6e-63 209.6 0.1 1.9e-22 79.1 0.0 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_7 PF13499.6 CBZ39101.1 - 2.2e-05 24.8 0.2 0.00031 21.1 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 CBZ39101.1 - 8.9e-05 22.3 0.5 0.11 12.4 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain pair Mac-1 PF09028.10 CBZ39101.1 - 0.056 12.5 0.1 0.093 11.8 0.1 1.3 1 0 0 1 1 1 0 Mac 1 MTHFR PF02219.17 CBZ39102.1 - 1.8e-89 299.9 0.0 2.1e-89 299.6 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Toxin_22 PF08092.11 CBZ39102.1 - 0.15 12.1 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 Magi peptide toxin family YAcAr PF10686.9 CBZ39102.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Ribosomal_S8e PF01201.22 CBZ39103.1 - 2.4e-45 154.0 3.3 2.4e-45 154.0 3.3 1.5 1 1 1 2 2 2 1 Ribosomal protein S8e DUF3746 PF12562.8 CBZ39103.1 - 0.076 12.9 0.5 0.41 10.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3746) CCDC-167 PF15188.6 CBZ39103.1 - 0.32 11.4 3.0 0.68 10.3 3.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ribosomal_L26 PF16906.5 CBZ39103.1 - 1.3 9.5 6.4 21 5.6 0.1 2.4 2 0 0 2 2 2 0 Ribosomal proteins L26 eukaryotic, L24P archaeal HU-CCDC81_euk_2 PF18289.1 CBZ39104.1 - 7.6e-08 32.4 0.0 1.4e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 TB2_DP1_HVA22 PF03134.19 CBZ39105.1 - 0.047 13.6 0.5 0.074 13.0 0.5 1.4 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Sec23_trunk PF04811.15 CBZ39106.1 - 4.4e-50 170.5 0.0 6.9e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CBZ39106.1 - 2.6e-22 78.6 0.0 1.7e-21 76.0 0.1 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CBZ39106.1 - 8.5e-21 74.5 0.9 8.5e-21 74.5 0.9 2.3 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CBZ39106.1 - 1.1e-11 44.6 0.7 2.6e-11 43.4 0.7 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CBZ39106.1 - 2.1e-05 24.3 0.6 5.5e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CBZ39106.1 - 0.34 10.3 2.1 0.27 10.7 0.3 1.8 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF1539 PF07560.11 CBZ39107.1 - 0.032 14.3 0.5 0.39 10.8 0.1 2.1 1 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) ComP_DUS PF16732.5 CBZ39107.1 - 0.35 11.8 2.0 0.65 10.9 0.3 2.2 3 0 0 3 3 3 0 Type IV minor pilin ComP, DNA uptake sequence receptor His_Phos_2 PF00328.22 CBZ39109.1 - 0.29 10.5 0.3 0.39 10.0 0.3 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Pkinase PF00069.25 CBZ39111.1 - 3.2e-62 210.3 0.0 3.7e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CBZ39111.1 - 3.7e-25 88.7 0.0 5.1e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CBZ39111.1 - 3.6e-09 36.3 0.0 7.6e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CBZ39111.1 - 4.5e-05 22.9 0.7 9.9e-05 21.8 0.7 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CBZ39111.1 - 0.048 13.2 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CBZ39111.1 - 0.063 13.2 0.5 0.73 9.7 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CBZ39111.1 - 0.13 11.1 0.2 0.18 10.7 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain His_Phos_2 PF00328.22 CBZ39112.1 - 6.5e-12 45.5 5.2 2.7e-07 30.3 0.1 3.1 1 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) UFD1 PF03152.14 CBZ39113.1 - 1.8e-46 157.8 0.0 2.3e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 PCI PF01399.27 CBZ39115.1 - 0.014 15.9 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 PCI domain MFS_1 PF07690.16 CBZ39117.1 - 0.011 14.7 6.5 0.014 14.4 6.5 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily Phage_holin_3_6 PF07332.11 CBZ39117.1 - 0.1 12.6 3.5 0.26 11.3 2.0 2.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SdpI PF13630.6 CBZ39117.1 - 0.35 11.0 7.7 0.13 12.4 4.7 1.8 1 1 1 2 2 2 0 SdpI/YhfL protein family SLC3A2_N PF16028.5 CBZ39117.1 - 1.9 8.1 8.5 2.2 7.9 1.9 2.5 1 1 1 2 2 2 0 Solute carrier family 3 member 2 N-terminus ZapB PF06005.12 CBZ39118.1 - 2.4 8.6 6.6 0.77 10.2 0.4 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Myb_DNA-bind_7 PF15963.5 CBZ39119.1 - 3e-24 84.7 0.4 5.6e-24 83.9 0.4 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CBZ39119.1 - 1.6e-05 25.0 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CBZ39119.1 - 0.14 12.4 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain DLH PF01738.18 CBZ39120.1 - 6e-22 78.3 0.0 7.7e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CBZ39120.1 - 0.0073 16.0 0.0 0.015 15.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3530 PF12048.8 CBZ39120.1 - 0.053 12.9 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) BAAT_C PF08840.11 CBZ39120.1 - 0.067 13.1 0.0 0.095 12.6 0.0 1.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1847 PF08901.11 CBZ39120.1 - 0.16 11.6 0.0 5.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1847) PCMT PF01135.19 CBZ39121.1 - 1.7e-46 158.7 0.0 2.2e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4491 PF14898.6 CBZ39121.1 - 0.0014 19.0 0.3 0.76 10.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4491) Methyltransf_32 PF13679.6 CBZ39121.1 - 0.0042 17.1 0.0 0.0065 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 CBZ39121.1 - 0.012 16.6 0.0 0.02 15.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CBZ39121.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CBZ39121.1 - 0.083 13.6 0.0 0.15 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CBZ39121.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ACBP PF00887.19 CBZ39122.1 - 1.7e-14 53.8 0.9 2.5e-14 53.3 0.2 1.7 2 0 0 2 2 2 1 Acyl CoA binding protein SRP-alpha_N PF04086.13 CBZ39122.1 - 0.11 12.4 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF5320 PF17253.2 CBZ39123.1 - 0.098 13.7 0.7 0.098 13.7 0.7 2.1 2 1 1 3 3 3 0 Family of unknown function (DUF5320) FXMRP1_C_core PF12235.8 CBZ39123.1 - 0.92 10.2 4.5 1.1 9.9 0.2 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal zf-PARP PF00645.18 CBZ39124.1 - 0.013 16.3 0.0 0.021 15.7 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region NYD-SP28_assoc PF14775.6 CBZ39125.1 - 3.7e-20 71.8 2.5 3.7e-20 71.8 2.5 4.2 5 1 1 6 6 6 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 CBZ39125.1 - 1.4e-17 63.6 6.4 1.4e-17 63.6 6.4 5.2 4 1 1 5 5 5 2 Sperm tail Ovate PF04844.13 CBZ39125.1 - 0.04 13.9 0.1 20 5.2 0.0 3.3 2 1 1 3 3 3 0 Transcriptional repressor, ovate FliD_C PF07195.12 CBZ39125.1 - 2 7.8 23.1 0.29 10.5 5.4 3.6 2 2 0 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF948 PF06103.11 CBZ39125.1 - 3.9 7.8 7.3 16 5.9 0.4 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Mito_carr PF00153.27 CBZ39127.1 - 1.7e-33 114.4 4.3 7.1e-13 48.3 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein SAS-6_N PF16531.5 CBZ39130.1 - 8.2e-24 84.0 0.3 1.2e-23 83.5 0.3 1.2 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Pneumo_matrix PF03393.16 CBZ39130.1 - 0.022 14.0 0.0 0.049 12.8 0.0 1.6 1 1 1 2 2 2 0 Pneumovirus matrix protein CSD PF00313.22 CBZ39130.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Metalloenzyme PF01676.18 CBZ39131.1 - 8e-80 267.8 0.0 9.2e-80 267.6 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 CBZ39131.1 - 2.6e-61 206.8 0.0 3.8e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 CBZ39131.1 - 7.7e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 CBZ39131.1 - 0.00061 19.9 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 PglZ domain Alk_phosphatase PF00245.20 CBZ39131.1 - 0.047 12.6 0.1 0.11 11.4 0.1 1.5 1 0 0 1 1 1 0 Alkaline phosphatase Sulfatase PF00884.23 CBZ39131.1 - 0.11 11.8 0.1 1.6 8.1 0.0 2.5 2 1 0 3 3 3 0 Sulfatase DUF3659 PF12396.8 CBZ39131.1 - 1.5 8.8 4.3 2.8 7.9 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3659) FtsJ PF01728.19 CBZ39132.1 - 8.4e-28 97.7 0.0 1.3e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cyt-b5 PF00173.28 CBZ39133.1 - 3.7e-11 43.0 0.0 4.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4239 PF14023.6 CBZ39134.1 - 0.013 15.3 4.3 0.016 14.9 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) bZIP_2 PF07716.15 CBZ39134.1 - 0.065 13.3 3.0 0.065 13.3 3.0 3.5 3 1 0 3 3 3 0 Basic region leucine zipper DUF812 PF05667.11 CBZ39134.1 - 0.074 11.9 14.9 0.11 11.3 14.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Val_tRNA-synt_C PF10458.9 CBZ39134.1 - 0.076 13.3 0.1 0.076 13.3 0.1 3.8 3 1 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm EOS1 PF12326.8 CBZ39134.1 - 0.076 12.9 0.6 0.11 12.4 0.6 1.2 1 0 0 1 1 1 0 N-glycosylation protein DUF4407 PF14362.6 CBZ39134.1 - 0.2 11.0 10.8 0.23 10.8 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ax_dynein_light PF10211.9 CBZ39134.1 - 0.35 10.8 15.5 0.37 10.7 1.4 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain FAM76 PF16046.5 CBZ39134.1 - 0.39 10.0 8.6 0.32 10.3 7.7 1.4 1 1 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 CBZ39134.1 - 1.9 7.3 17.6 0.17 10.7 5.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein GrpE PF01025.19 CBZ39134.1 - 2.5 7.7 14.7 0.13 11.9 0.4 2.2 1 1 1 2 2 2 0 GrpE UPF0242 PF06785.11 CBZ39134.1 - 2.7 8.0 15.1 5.3 7.1 15.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 CBZ39134.1 - 3.2 8.4 11.9 13 6.5 0.6 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Exonuc_VII_L PF02601.15 CBZ39134.1 - 3.4 7.1 8.7 4 6.9 8.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ACCA PF03255.14 CBZ39134.1 - 6 6.7 10.1 12 5.7 4.5 2.4 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spc24 PF08286.11 CBZ39134.1 - 9.4 6.5 11.9 18 5.6 4.9 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Solute_trans_a PF03619.16 CBZ39135.1 - 4.8e-78 262.3 19.1 4.8e-78 262.3 19.1 1.3 2 0 0 2 2 2 1 Organic solute transporter Ostalpha NUFIP1 PF10453.9 CBZ39135.1 - 0.35 10.7 0.6 0.64 9.9 0.6 1.3 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) AAA_16 PF13191.6 CBZ39136.1 - 9.8e-07 29.3 1.0 0.00025 21.5 0.1 3.0 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 CBZ39136.1 - 1.1e-05 25.8 0.0 4e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CBZ39136.1 - 0.015 15.6 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CBZ39136.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DNA_pol3_delta2 PF13177.6 CBZ39137.1 - 4.2e-14 52.7 0.0 6.4e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CBZ39137.1 - 2.1e-07 31.4 0.0 8.1e-07 29.5 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CBZ39137.1 - 0.00018 21.9 0.0 0.00036 20.9 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_24 PF13479.6 CBZ39137.1 - 0.00026 20.8 0.0 0.00062 19.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CBZ39137.1 - 0.0026 17.7 0.1 0.026 14.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CBZ39137.1 - 0.0028 17.6 0.0 0.0061 16.5 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 CBZ39137.1 - 0.004 16.6 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CBZ39137.1 - 0.0045 17.4 0.0 0.18 12.2 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CBZ39137.1 - 0.016 14.9 0.1 0.52 10.0 0.0 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 CBZ39137.1 - 0.033 14.3 0.0 0.83 9.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.6 CBZ39137.1 - 0.054 13.8 0.1 0.24 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CBZ39137.1 - 0.072 12.8 0.0 6 6.5 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Mito_carr PF00153.27 CBZ39138.1 - 6.4e-24 83.7 1.3 1.1e-11 44.5 0.2 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein BCNT PF07572.12 CBZ39139.1 - 0.045 13.8 0.5 0.13 12.4 0.5 1.8 1 0 0 1 1 1 0 Bucentaur or craniofacial development HTH_15 PF12324.8 CBZ39139.1 - 0.14 12.1 0.1 0.45 10.5 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Peptidase_S9_N PF02897.15 CBZ39141.1 - 2.3e-98 329.7 6.3 3.2e-98 329.3 6.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 CBZ39141.1 - 3.7e-64 216.1 0.0 7.1e-64 215.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 CBZ39141.1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF4019 PF13211.6 CBZ39141.1 - 0.022 15.1 0.3 3.6 8.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) Abhydrolase_3 PF07859.13 CBZ39141.1 - 0.047 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CBZ39141.1 - 0.091 12.4 0.0 0.42 10.2 0.1 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold OSCP PF00213.18 CBZ39142.1 - 3.8e-07 30.4 0.2 1.4e-06 28.5 0.2 1.9 1 1 0 1 1 1 1 ATP synthase delta (OSCP) subunit Adaptin_N PF01602.20 CBZ39143.1 - 1.4e-101 340.6 4.2 1.8e-101 340.3 4.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CBZ39143.1 - 1.4e-48 165.0 0.3 8.1e-47 159.3 0.0 2.7 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CBZ39143.1 - 1.9e-11 44.2 4.4 1.2e-06 28.8 0.0 4.9 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 CBZ39143.1 - 1.2e-07 31.4 3.6 0.046 14.0 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat RIX1 PF08167.12 CBZ39143.1 - 0.00039 20.2 1.6 0.12 12.2 0.2 3.5 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis RTP1_C1 PF10363.9 CBZ39143.1 - 0.00077 19.6 0.9 0.27 11.5 0.0 3.5 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 VHS PF00790.19 CBZ39143.1 - 0.004 17.0 0.5 0.011 15.6 0.1 2.0 2 0 0 2 2 2 1 VHS domain PD-C2-AF1 PF09310.10 CBZ39143.1 - 0.093 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 HEAT_EZ PF13513.6 CBZ39143.1 - 0.15 12.6 2.8 13 6.4 0.1 4.6 2 1 2 4 4 4 0 HEAT-like repeat CAP18_C PF12153.8 CBZ39143.1 - 0.26 11.2 1.2 0.63 10.0 1.2 1.6 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) NIF PF03031.18 CBZ39144.1 - 1.5e-31 109.3 0.0 2.1e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 CBZ39144.1 - 0.089 13.1 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AFG1_ATPase PF03969.16 CBZ39146.1 - 2.2e-56 191.3 4.0 9.7e-56 189.2 0.1 2.4 3 0 0 3 3 3 2 AFG1-like ATPase AAA_16 PF13191.6 CBZ39146.1 - 0.00015 22.2 1.0 0.00077 19.9 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CBZ39146.1 - 0.15 12.3 0.0 1.6 9.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CBZ39146.1 - 0.15 12.3 0.1 4.4 7.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF1289 PF06945.13 CBZ39146.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) E3_UFM1_ligase PF09743.9 CBZ39147.1 - 3e-67 227.1 0.0 4.5e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 4HBT PF03061.22 CBZ39148.1 - 1.7e-05 25.1 0.0 2.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 CBZ39148.1 - 0.00039 20.6 0.0 0.00054 20.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) SET PF00856.28 CBZ39149.1 - 2.9e-05 24.5 0.0 0.0006 20.2 0.0 2.2 1 1 0 1 1 1 1 SET domain Aa_trans PF01490.18 CBZ39150.1 - 9.3e-41 139.9 34.0 1.1e-40 139.6 34.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MuF_C PF18819.1 CBZ39150.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.2 1 0 0 1 1 1 0 Phage MuF-C-terminal domain TMEM65 PF10507.9 CBZ39151.1 - 2.3e-37 127.3 3.3 5.8e-37 126.0 3.3 1.7 1 0 0 1 1 1 1 Transmembrane protein 65 EF-hand_1 PF00036.32 CBZ39151.1 - 7e-08 31.5 0.4 0.0018 17.7 0.0 3.4 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CBZ39151.1 - 1.3e-05 24.7 0.3 0.019 14.8 0.0 3.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 CBZ39151.1 - 0.0018 18.7 2.2 0.6 10.6 0.1 2.8 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_14 PF17959.1 CBZ39151.1 - 0.0019 18.5 0.3 0.0085 16.4 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 CBZ39151.1 - 0.015 14.8 0.8 0.28 10.7 0.0 3.0 3 0 0 3 3 3 0 EF hand Ppx-GppA PF02541.16 CBZ39151.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DUF2514 PF10721.9 CBZ39151.1 - 1.7 8.7 13.3 0.41 10.7 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) RNA_lig_T4_1 PF09511.10 CBZ39153.1 - 3e-29 102.5 0.0 6.4e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 CBZ39153.1 - 2.2e-09 37.6 0.2 5.1e-09 36.4 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CBZ39153.1 - 1.5e-06 28.8 0.0 3.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CBZ39153.1 - 5e-05 23.3 0.1 0.00019 21.4 0.1 2.0 1 0 0 1 1 1 1 NACHT domain 6PF2K PF01591.18 CBZ39153.1 - 6.8e-05 22.3 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase APS_kinase PF01583.20 CBZ39153.1 - 0.00011 22.1 0.0 0.00033 20.6 0.0 1.9 1 1 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.10 CBZ39153.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ABC_tran PF00005.27 CBZ39153.1 - 0.0025 18.3 0.0 0.013 16.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 CBZ39153.1 - 0.033 14.6 0.3 0.14 12.6 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 CBZ39153.1 - 0.038 13.6 3.9 0.12 12.0 0.5 3.0 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 CBZ39153.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CPT PF07931.12 CBZ39153.1 - 0.044 13.6 0.3 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.12 CBZ39153.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 CBZ39153.1 - 0.082 12.2 0.0 0.18 11.1 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 CBZ39153.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain ComP_DUS PF16732.5 CBZ39153.1 - 0.16 12.9 0.1 0.66 10.9 0.1 2.1 1 0 0 1 1 1 0 Type IV minor pilin ComP, DNA uptake sequence receptor LAM_C PF12544.8 CBZ39153.1 - 0.22 11.7 0.0 0.46 10.7 0.0 1.4 1 0 0 1 1 1 0 Lysine-2,3-aminomutase EVE PF01878.18 CBZ39155.1 - 7e-52 175.3 0.2 9.5e-52 174.9 0.2 1.2 1 0 0 1 1 1 1 EVE domain LPD28 PF18843.1 CBZ39155.1 - 0.082 12.5 0.0 0.22 11.2 0.0 1.6 1 1 0 1 1 1 0 Large polyvalent protein associated domain 28 Bromodomain PF00439.25 CBZ39156.1 - 2.1e-18 66.2 0.1 3.4e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 Bromodomain Mqo PF06039.15 CBZ39156.1 - 0.06 11.9 0.2 0.082 11.5 0.2 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Nucleoporin_N PF08801.11 CBZ39157.1 - 1.8e-59 201.7 0.0 2.8e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like LRR_8 PF13855.6 CBZ39158.1 - 0.0065 16.2 0.4 0.028 14.2 0.1 2.3 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 CBZ39158.1 - 0.081 13.4 0.0 1.1 9.8 0.0 2.6 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) Cpn60_TCP1 PF00118.24 CBZ39159.1 - 1.5e-153 512.0 11.2 1.7e-153 511.8 11.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF374 PF04028.13 CBZ39159.1 - 0.034 13.7 0.2 0.21 11.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF374) eIF3_subunit PF08597.10 CBZ39159.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Ribosomal_L1 PF00687.21 CBZ39160.1 - 4.3e-20 72.3 0.0 5.5e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-C2H2_6 PF13912.6 CBZ39161.1 - 6.8e-09 35.5 12.3 6.1e-08 32.5 2.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CBZ39161.1 - 0.0008 20.0 11.4 0.0066 17.2 2.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CBZ39161.1 - 0.0015 18.1 1.3 0.048 13.3 0.1 2.3 2 0 0 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 CBZ39161.1 - 0.0046 17.3 9.9 0.042 14.3 2.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 CBZ39161.1 - 0.018 15.5 5.3 0.48 10.9 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CBZ39161.1 - 0.04 14.2 0.7 3.1 8.2 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 CBZ39161.1 - 0.047 14.0 1.0 5.3 7.4 0.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Vps39_2 PF10367.9 CBZ39161.1 - 0.13 12.7 0.1 17 5.9 0.0 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 SSB PF00436.25 CBZ39161.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Single-strand binding protein family DUF629 PF04780.12 CBZ39161.1 - 0.7 8.4 2.4 2 6.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.8 CBZ39161.1 - 1 9.7 3.9 20 5.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CBZ39161.1 - 1.3 9.6 9.7 3.1 8.4 0.2 3.3 4 0 0 4 4 3 0 Zinc-finger double domain HEPN_SAV2148 PF18725.1 CBZ39162.1 - 0.089 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 SAV2148-like HEPN Thioredoxin PF00085.20 CBZ39163.1 - 1.7e-61 204.6 0.5 2.8e-31 107.6 0.0 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CBZ39163.1 - 4.4e-28 98.4 0.1 5.9e-14 52.4 0.0 3.6 2 2 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CBZ39163.1 - 1.4e-13 51.3 2.5 6.3e-06 26.6 0.2 3.9 2 2 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CBZ39163.1 - 3.1e-09 37.0 0.8 0.06 13.7 0.0 4.6 4 2 2 6 6 6 3 Thioredoxin-like Thioredoxin_7 PF13899.6 CBZ39163.1 - 3.4e-09 36.7 0.0 0.0014 18.8 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CBZ39163.1 - 4.6e-08 33.0 0.6 0.016 15.1 0.0 3.2 2 1 1 3 3 3 2 AhpC/TSA family OST3_OST6 PF04756.13 CBZ39163.1 - 2.6e-07 30.3 0.0 0.0013 18.2 0.0 2.6 2 1 0 2 2 2 2 OST3 / OST6 family, transporter family TraF PF13728.6 CBZ39163.1 - 8.1e-06 25.8 0.0 0.0095 15.8 0.0 3.4 3 1 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CBZ39163.1 - 1.9e-05 24.5 0.0 0.041 13.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_3 PF13192.6 CBZ39163.1 - 0.00035 20.6 0.0 1.7 8.7 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin domain Redoxin PF08534.10 CBZ39163.1 - 0.00079 19.2 0.6 0.34 10.6 0.0 3.3 3 0 0 3 3 3 1 Redoxin Calsequestrin PF01216.17 CBZ39163.1 - 0.0016 17.6 0.3 0.0084 15.2 0.3 1.9 2 0 0 2 2 2 1 Calsequestrin HyaE PF07449.11 CBZ39163.1 - 0.013 15.5 0.0 0.19 11.7 0.0 2.8 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Phosphatase PF15698.5 CBZ39163.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphatase FA_desaturase PF00487.24 CBZ39164.1 - 5.1e-30 105.1 12.4 5.6e-30 105.0 11.8 1.3 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CBZ39164.1 - 1.3e-10 41.3 0.0 2.7e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2208 PF09973.9 CBZ39165.1 - 0.17 11.5 0.8 0.33 10.5 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) KxDL PF10241.9 CBZ39165.1 - 1.9 8.8 27.5 0.11 12.8 4.7 5.0 4 2 2 6 6 6 0 Uncharacterized conserved protein Methyltransf_23 PF13489.6 CBZ39166.1 - 0.042 13.7 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain eIF-3c_N PF05470.12 CBZ39167.1 - 1.5e-20 73.1 0.8 4.2e-16 58.4 0.0 2.4 1 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRM_1 PF00076.22 CBZ39168.1 - 0.00053 19.8 0.0 0.0014 18.4 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CBZ39168.1 - 0.0096 15.5 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CBZ39168.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 RRM_occluded PF16842.5 CBZ39168.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif MOZ_SAS PF01853.18 CBZ39169.1 - 3.2e-47 160.5 0.0 4.1e-47 160.2 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CBZ39169.1 - 0.0058 16.2 1.6 0.011 15.4 1.6 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CBZ39169.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CBZ39169.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.25 CBZ39169.1 - 0.04 14.2 0.0 0.075 13.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family zf-met PF12874.7 CBZ39169.1 - 0.075 13.5 2.9 0.15 12.4 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C4_ClpX PF06689.13 CBZ39169.1 - 0.11 12.4 1.4 0.25 11.2 1.4 1.5 1 0 0 1 1 1 0 ClpX C4-type zinc finger PSP1 PF04468.12 CBZ39171.1 - 1.5e-27 95.6 0.2 2.7e-27 94.9 0.2 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_donovani-ASM22713v2/GCA_000227135.2_ASM22713v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_donovani-ASM22713v2/GCA_000227135.2_ASM22713v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_donovani-ASM22713v2/GCA_000227135.2_ASM22713v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Kinetoplastida/Leishmania_donovani-ASM22713v2/GCA_000227135.2_ASM22713v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 08:38:27 2019 # [ok]