# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- DUP PF00674.18 CAR25450.1 - 5.8e-09 36.0 0.2 5.8e-09 36.0 0.2 2.6 3 0 0 3 3 3 1 DUP family TctB PF07331.11 CAR25450.1 - 0.0096 16.2 1.2 1.8 8.8 0.2 2.3 2 0 0 2 2 2 2 Tripartite tricarboxylate transporter TctB family DUP PF00674.18 CAR25452.1 - 2.6e-08 34.0 0.6 2.6e-08 34.0 0.6 2.1 2 0 0 2 2 2 1 DUP family DUP PF00674.18 CAR25453.1 - 1.2e-33 115.3 11.5 4.7e-17 62.0 3.2 2.9 2 2 0 2 2 2 2 DUP family DUP PF00674.18 CAR25454.1 - 2.2e-07 30.9 0.2 2.2e-07 30.9 0.2 2.4 2 0 0 2 2 2 1 DUP family DUF4532 PF15046.6 CAR25454.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) Aldo_ket_red PF00248.21 CAR25456.1 - 5e-60 203.2 0.0 5.9e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family AA_permease PF00324.21 CAR25457.1 - 5e-122 407.9 37.0 5.9e-122 407.7 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR25457.1 - 1.8e-33 116.0 40.7 2.3e-33 115.7 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease HTH_49 PF18010.1 CAR25457.1 - 0.014 15.2 0.1 0.033 14.0 0.1 1.6 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain MFS_1 PF07690.16 CAR25458.1 - 9e-44 149.8 40.2 5.3e-43 147.3 40.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR25458.1 - 1.6e-17 63.5 16.8 5.8e-17 61.7 7.4 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 CAR25458.1 - 4.3e-06 25.4 12.5 7.9e-06 24.6 12.5 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cation_ATPase_C PF00689.21 CAR25458.1 - 0.00027 20.7 1.1 0.00027 20.7 1.1 2.9 3 1 1 4 4 4 1 Cation transporting ATPase, C-terminus MFS_1 PF07690.16 CAR25459.1 - 1.4e-21 76.8 12.3 2.1e-21 76.2 12.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CAR25459.1 - 0.0007 18.6 1.7 0.0013 17.7 1.7 1.4 1 0 0 1 1 1 1 MFS_1 like family DUF997 PF06196.12 CAR25459.1 - 0.044 13.8 2.1 0.068 13.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF997) adh_short PF00106.25 CAR25460.1 - 9.1e-47 159.0 1.7 1.1e-46 158.8 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR25460.1 - 5.8e-35 120.9 0.4 7.1e-35 120.6 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR25460.1 - 1.2e-12 48.1 1.1 1.7e-12 47.6 1.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CAR25460.1 - 1.9e-05 24.3 0.1 0.001 18.6 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CAR25460.1 - 3.3e-05 23.2 0.3 4e-05 22.9 0.3 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CAR25460.1 - 0.00018 21.5 0.4 0.00027 20.9 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CAR25460.1 - 0.036 13.1 0.4 0.051 12.6 0.4 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CAR25460.1 - 0.085 12.2 0.1 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans_2 PF11951.8 CAR25461.1 - 4.9e-103 344.9 3.4 7e-103 344.4 3.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR25461.1 - 3e-12 46.4 7.4 7.1e-12 45.2 7.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIID-18kDa PF02269.16 CAR25462.1 - 6.6e-33 112.6 0.0 9.4e-33 112.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.24 CAR25462.1 - 0.0086 16.4 2.2 0.068 13.5 0.0 2.7 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CAR25462.1 - 0.073 13.2 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 CAR25462.1 - 0.13 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CDC45 PF02724.14 CAR25462.1 - 0.27 9.5 6.5 0.24 9.6 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein ERO1 PF04137.15 CAR25463.1 - 3.8e-119 398.0 1.0 5.4e-119 397.5 1.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) VPS9 PF02204.18 CAR25464.1 - 7.9e-27 93.5 0.3 1.6e-26 92.5 0.3 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.16 CAR25464.1 - 3.3e-11 42.6 0.0 8.1e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 CUE domain DUF5601 PF18151.1 CAR25464.1 - 4.4e-09 36.5 0.9 1.1e-08 35.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) Asn_synthase PF00733.21 CAR25465.1 - 3.4e-23 82.9 0.1 2.3e-13 50.6 0.0 2.8 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CAR25465.1 - 1.8e-09 37.5 0.4 1.1e-07 31.8 0.3 2.8 2 1 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CAR25465.1 - 6.8e-05 23.1 0.0 0.00049 20.3 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CAR25465.1 - 0.16 11.4 0.1 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 Aluminium induced protein Rad10 PF03834.14 CAR25466.1 - 3.6e-36 123.7 1.1 5.2e-36 123.1 1.1 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Prefoldin PF02996.17 CAR25467.1 - 3.1e-25 88.4 1.4 3.2e-25 88.4 0.9 1.3 1 1 0 1 1 1 1 Prefoldin subunit E2F_CC-MB PF16421.5 CAR25467.1 - 0.035 14.5 3.5 0.055 13.8 0.1 2.2 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain PHM7_cyt PF14703.6 CAR25467.1 - 0.078 13.2 7.0 0.11 12.8 7.0 1.5 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter HAUS6_N PF14661.6 CAR25467.1 - 0.12 12.0 6.7 0.45 10.0 2.8 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus PilJ PF13675.6 CAR25467.1 - 0.79 9.8 9.4 2.2 8.3 0.9 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Utp14 PF04615.13 CAR25468.1 - 3.5e-190 634.3 83.5 3.5e-190 634.3 83.5 2.1 1 1 1 2 2 2 1 Utp14 protein Proteasome PF00227.26 CAR25469.1 - 2.7e-60 203.1 0.0 3.3e-60 202.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR25469.1 - 7.8e-10 38.2 0.9 1.6e-09 37.3 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RRM_1 PF00076.22 CAR25470.1 - 8.8e-06 25.5 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 CAR25470.1 - 5.4e-05 23.0 1.5 5.4e-05 23.0 1.5 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CAR25470.1 - 0.23 12.2 2.7 0.45 11.2 2.7 1.6 1 1 0 1 1 1 0 Torus domain zf_CCCH_4 PF18345.1 CAR25470.1 - 0.57 10.3 6.3 0.72 10.0 3.5 2.3 2 0 0 2 2 2 0 Zinc finger domain COX14 PF14880.6 CAR25471.1 - 2.8e-24 84.7 0.4 3.1e-24 84.6 0.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Ish1 PF10281.9 CAR25472.1 - 4.1e-38 129.4 19.0 3.4e-08 33.6 1.3 6.9 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein SAP PF02037.27 CAR25472.1 - 0.0015 18.3 0.2 0.93 9.3 0.1 4.6 4 1 0 4 4 4 1 SAP domain SAP30_Sin3_bdg PF13867.6 CAR25472.1 - 0.022 15.1 0.3 0.3 11.4 0.0 2.9 4 0 0 4 4 4 0 Sin3 binding region of histone deacetylase complex subunit SAP30 HeH PF12949.7 CAR25472.1 - 0.074 12.8 0.3 5.3 6.9 0.0 3.3 3 0 0 3 3 3 0 HeH/LEM domain Xin PF08043.12 CAR25472.1 - 0.19 11.4 3.5 0.5 10.1 3.5 1.7 1 0 0 1 1 1 0 Xin repeat Remorin_C PF03763.13 CAR25472.1 - 0.45 10.4 0.0 0.45 10.4 0.0 3.4 4 0 0 4 4 4 0 Remorin, C-terminal region DUF445 PF04286.12 CAR25472.1 - 1.6 8.4 7.2 2.8 7.7 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF445) YtxH PF12732.7 CAR25472.1 - 8.5 7.0 10.8 63 4.2 1.8 4.9 3 2 0 3 3 3 0 YtxH-like protein Peptidase_M4 PF01447.18 CAR25473.1 - 0.023 15.2 0.0 0.042 14.3 0.0 1.3 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain RPM2 PF08579.11 CAR25474.1 - 9.3e-48 161.6 2.1 5.3e-47 159.1 2.1 2.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) HMG_CoA_synt_C PF08540.10 CAR25475.1 - 5.5e-114 380.5 3.2 7e-114 380.2 3.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 CAR25475.1 - 4.8e-92 306.6 0.3 6.8e-92 306.1 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal F-box-like PF12937.7 CAR25476.1 - 5.3e-12 45.4 0.8 1.1e-11 44.4 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAR25476.1 - 7.7e-08 32.0 0.6 7.7e-08 32.0 0.6 1.9 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 CAR25476.1 - 0.001 18.9 0.1 0.0025 17.7 0.1 1.6 1 0 0 1 1 1 1 F-box UIM PF02809.20 CAR25476.1 - 0.011 15.6 5.0 0.011 15.6 5.0 4.2 4 0 0 4 4 4 0 Ubiquitin interaction motif PRANC PF09372.10 CAR25476.1 - 0.017 15.4 0.1 0.037 14.4 0.1 1.6 1 0 0 1 1 1 0 PRANC domain Pex14_N PF04695.13 CAR25476.1 - 1.6 9.4 11.2 2.9 8.5 11.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NAD_binding_1 PF00175.21 CAR25477.1 - 1.4e-27 96.5 0.0 2.1e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CAR25477.1 - 7.1e-27 93.7 0.0 1.2e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CAR25477.1 - 3.1e-05 24.1 0.0 0.00026 21.1 0.0 2.3 2 1 1 3 3 3 1 Ferric reductase NAD binding domain ALO PF04030.14 CAR25478.1 - 1.5e-100 336.3 1.6 1.5e-100 336.3 1.6 1.4 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CAR25478.1 - 8.9e-29 100.0 0.0 1.3e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain UPF0180 PF03698.13 CAR25478.1 - 0.042 14.0 0.1 0.085 13.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Tubulin PF00091.25 CAR25480.1 - 1e-66 224.9 0.0 1.5e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAR25480.1 - 2.6e-50 169.8 0.1 4e-50 169.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Sugar_tr PF00083.24 CAR25481.1 - 6.3e-44 150.6 15.3 1.7e-29 103.0 6.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CAR25481.1 - 3.9e-19 68.8 26.2 3.1e-17 62.5 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TIL PF01826.17 CAR25481.1 - 0.017 15.3 0.4 0.017 15.3 0.4 1.8 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain SQS_PSY PF00494.19 CAR25482.1 - 3.2e-42 144.8 0.0 4.2e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Pept_tRNA_hydro PF01195.19 CAR25483.1 - 1.7e-40 138.8 0.0 2.1e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Gtr1_RagA PF04670.12 CAR25484.1 - 1.3e-94 315.9 1.8 1.7e-94 315.5 1.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CAR25484.1 - 1.7e-09 37.5 0.5 4.2e-09 36.2 0.1 1.8 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CAR25484.1 - 6.1e-09 36.1 0.1 1.7e-08 34.7 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR25484.1 - 3.2e-07 30.0 0.1 3.2e-07 30.0 0.1 1.9 3 0 0 3 3 3 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR25484.1 - 6.1e-07 29.5 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CAR25484.1 - 0.0093 16.5 0.1 0.02 15.4 0.1 1.8 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CAR25484.1 - 0.023 14.6 0.8 1.2 9.1 0.1 2.6 2 0 0 2 2 2 0 RsgA GTPase AIG1 PF04548.16 CAR25484.1 - 0.024 14.0 0.7 0.18 11.1 0.1 2.3 1 1 1 2 2 2 0 AIG1 family Guanylate_kin PF00625.21 CAR25484.1 - 0.031 13.9 1.1 0.38 10.4 1.1 2.3 1 1 0 1 1 1 0 Guanylate kinase AAA_29 PF13555.6 CAR25484.1 - 0.049 13.4 0.3 0.098 12.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bac_RepA_C PF18008.1 CAR25484.1 - 0.38 11.1 3.6 0.24 11.8 0.3 2.2 2 1 1 3 3 3 0 Replication initiator protein A C-terminal domain SUIM_assoc PF16619.5 CAR25485.1 - 0.007 16.4 2.4 0.007 16.4 2.4 2.4 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 tRNA-synt_2 PF00152.20 CAR25486.1 - 2.2e-65 220.8 0.0 2.7e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CAR25486.1 - 3.4e-05 23.4 0.2 0.00023 20.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 CAR25486.1 - 0.00083 19.3 0.0 0.002 18.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Mating_N PF12731.7 CAR25486.1 - 0.055 13.6 0.0 1.6 8.9 0.0 2.7 3 0 0 3 3 3 0 Mating-type protein beta 1 Ferric_reduct PF01794.19 CAR25487.1 - 4.5e-22 78.5 21.4 6.7e-22 77.9 18.7 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CAR25487.1 - 5.2e-15 55.9 0.1 8.4e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CAR25487.1 - 1.5e-13 50.8 0.1 5.4e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 FAD-binding domain RNase_HII PF01351.18 CAR25488.1 - 5e-62 209.3 0.0 6.1e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII 2-Hacid_dh_C PF02826.19 CAR25489.1 - 9.2e-31 106.6 0.0 5.5e-30 104.0 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CAR25489.1 - 0.00016 21.9 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 CAR25489.1 - 0.0018 17.6 0.1 0.035 13.4 0.0 2.1 1 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 CAR25489.1 - 0.012 16.2 0.0 0.044 14.4 0.0 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CAR25489.1 - 0.014 15.5 0.1 0.057 13.5 0.1 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CAR25489.1 - 0.015 15.6 0.0 0.17 12.1 0.0 2.7 1 1 2 3 3 3 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CAR25489.1 - 0.051 14.0 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-oxoacid_dh PF00198.23 CAR25490.1 - 5.1e-73 245.4 0.3 6.5e-73 245.0 0.3 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CAR25490.1 - 2.4e-16 59.3 0.2 5e-16 58.3 0.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CAR25490.1 - 3.4e-14 52.9 0.3 1.2e-13 51.2 0.3 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CAR25490.1 - 0.0044 16.8 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 Biotin-lipoyl like MSA-2c PF12238.8 CAR25490.1 - 0.025 14.6 4.9 0.045 13.8 4.9 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Tom7 PF08038.12 CAR25491.1 - 2.1e-19 68.9 0.2 2.8e-19 68.5 0.2 1.2 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.27 CAR25492.1 - 2.2e-59 197.4 3.8 1.2e-19 70.0 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L13 PF00572.18 CAR25493.1 - 1.3e-09 38.3 2.5 4.5e-08 33.4 0.2 2.7 2 1 0 2 2 2 1 Ribosomal protein L13 CSM2 PF16834.5 CAR25494.1 - 3.4e-67 225.9 0.3 4.1e-67 225.7 0.3 1.0 1 0 0 1 1 1 1 Shu complex component Csm2, DNA-binding Forkhead PF00250.18 CAR25495.1 - 1.2e-32 112.0 0.1 2.5e-32 111.0 0.1 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CAR25495.1 - 2.9e-10 40.3 0.0 8.1e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 CAR25495.1 - 0.0014 18.9 0.1 0.003 17.9 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family SBBP PF06739.11 CAR25495.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Beta-propeller repeat MOR2-PAG1_N PF14222.6 CAR25496.1 - 2e-181 604.7 5.5 2e-181 604.7 5.5 2.4 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 CAR25496.1 - 3.2e-87 292.6 0.5 3.2e-87 292.6 0.5 3.1 4 0 0 4 4 4 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 CAR25496.1 - 2.6e-18 65.1 23.4 1.8e-09 35.9 0.3 4.0 3 1 0 4 4 4 3 Cell morphogenesis central region Cnd1 PF12717.7 CAR25496.1 - 0.0092 16.0 4.9 0.018 15.1 0.1 3.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 STAR_dimer PF16544.5 CAR25496.1 - 0.24 11.0 1.2 0.92 9.1 1.2 2.0 1 0 0 1 1 1 0 Homodimerisation region of STAR domain protein Ribosomal_60s PF00428.19 CAR25496.1 - 0.68 10.6 5.2 2.3 8.8 4.7 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein RskA PF10099.9 CAR25496.1 - 8.8 6.6 9.5 0.74 10.1 0.3 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA MMS19_C PF12460.8 CAR25497.1 - 3.9e-94 316.2 13.8 3.9e-94 316.2 13.8 2.9 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 CAR25497.1 - 1.2e-87 293.9 7.4 1.8e-83 280.1 0.2 4.0 3 1 1 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 CAR25497.1 - 0.00078 19.9 0.2 2.4 8.8 0.0 3.8 4 0 0 4 4 4 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CAR25497.1 - 0.0021 18.6 1.9 0.093 13.3 0.0 4.0 3 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region DUF4325 PF14213.6 CAR25497.1 - 0.0084 15.8 0.0 0.61 9.8 0.0 3.3 2 0 0 2 2 2 1 STAS-like domain of unknown function (DUF4325) WAPL PF07814.13 CAR25497.1 - 0.011 14.5 5.2 0.016 14.0 3.6 2.0 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin Cnd1 PF12717.7 CAR25497.1 - 0.026 14.5 14.8 0.29 11.2 0.3 5.4 5 3 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CAR25497.1 - 0.031 14.4 3.4 0.23 11.7 0.2 3.4 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Condensin2nSMC PF12422.8 CAR25497.1 - 0.051 13.8 0.3 0.44 10.7 0.1 2.8 1 1 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit APAF1_C PF17908.1 CAR25497.1 - 0.081 12.9 0.1 0.26 11.3 0.1 1.8 1 0 0 1 1 1 0 APAF-1 helical domain RRT14 PF17075.5 CAR25498.1 - 8.3e-62 208.8 23.3 9.8e-62 208.6 23.3 1.0 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 SNF2_N PF00176.23 CAR25499.1 - 2e-73 247.1 0.3 2e-73 247.1 0.3 2.2 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR25499.1 - 2.8e-24 85.6 0.5 7.6e-20 71.3 0.0 3.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Bromodomain PF00439.25 CAR25499.1 - 1e-20 73.6 0.2 3.7e-20 71.8 0.2 2.0 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 CAR25499.1 - 1.1e-10 41.8 0.0 1.1e-10 41.8 0.0 3.8 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit SnAC PF14619.6 CAR25499.1 - 5.4e-10 39.8 0.0 5.4e-10 39.8 0.0 4.3 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.13 CAR25499.1 - 0.00013 22.2 10.6 0.00013 22.2 10.6 4.2 3 2 1 4 4 4 1 HSA COMP PF11598.8 CAR25499.1 - 0.76 10.3 5.2 19 5.8 0.5 3.5 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein Ribosomal_S13 PF00416.22 CAR25499.1 - 7.4 7.0 13.6 0.18 12.2 4.2 3.0 2 0 0 2 2 2 0 Ribosomal protein S13/S18 CBFB_NFYA PF02045.15 CAR25499.1 - 7.7 7.2 10.3 4.3 8.0 1.3 4.0 3 0 0 3 3 3 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ribosomal_L6 PF00347.23 CAR25500.1 - 1.5e-26 92.9 7.3 7.6e-13 49.0 0.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Transket_pyr PF02779.24 CAR25501.1 - 4.7e-66 221.8 0.0 9.8e-66 220.8 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CAR25501.1 - 2.1e-56 191.1 0.0 2.9e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CAR25501.1 - 5.9e-49 165.7 0.0 9.9e-49 164.9 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CAR25501.1 - 2.2e-19 68.8 2.7 2.2e-19 68.8 2.7 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus adh_short PF00106.25 CAR25502.1 - 1.4e-44 151.9 0.1 1.9e-44 151.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR25502.1 - 3.5e-28 98.8 0.0 4.4e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR25502.1 - 1.7e-09 37.9 0.1 2.4e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CAR25502.1 - 3e-06 26.9 0.9 1.4e-05 24.7 0.9 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CAR25502.1 - 8.2e-05 22.1 0.2 0.00083 18.8 0.2 2.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 CAR25502.1 - 0.0017 17.5 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CAR25502.1 - 0.013 14.9 0.4 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CAR25502.1 - 0.03 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Cas_Cas1 PF01867.16 CAR25502.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR associated protein Cas1 SUN PF03856.13 CAR25503.1 - 1.7e-97 325.7 14.8 3.4e-97 324.7 14.8 1.5 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) RNA_pol_Rpb4 PF03874.16 CAR25504.1 - 0.081 13.3 1.2 0.19 12.1 1.2 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb4 MFS_1 PF07690.16 CAR25505.1 - 4.5e-43 147.5 26.1 1.1e-39 136.4 11.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR25505.1 - 4.7e-09 35.6 12.8 4.7e-09 35.6 12.8 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 CAR25505.1 - 0.0041 15.6 4.6 0.0067 14.9 4.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DnaJ_C PF01556.18 CAR25506.1 - 7.4e-41 139.7 0.3 9.4e-41 139.3 0.3 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAR25506.1 - 1e-25 89.6 2.2 1.7e-25 88.9 2.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAR25506.1 - 2.7e-16 59.7 17.6 4.2e-16 59.1 17.6 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CAR25506.1 - 0.011 15.7 2.8 0.011 15.7 2.8 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein LprI PF07007.12 CAR25506.1 - 0.13 12.9 0.0 0.26 12.0 0.0 1.4 1 0 0 1 1 1 0 Lysozyme inhibitor LprI HypA PF01155.19 CAR25506.1 - 2 8.5 10.6 5.2 7.1 1.9 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA MTS PF05175.14 CAR25507.1 - 3.9e-09 36.3 0.0 7.2e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CAR25507.1 - 1.2e-05 25.1 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR25507.1 - 1.7e-05 25.5 0.0 3.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 CAR25507.1 - 0.11 13.1 0.1 0.24 12.0 0.1 1.6 1 0 0 1 1 1 0 PrmC N-terminal domain Methyltransf_16 PF10294.9 CAR25507.1 - 0.21 11.3 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Gcd10p PF04189.13 CAR25508.1 - 6e-102 340.8 1.2 8.4e-102 340.3 1.2 1.2 1 0 0 1 1 1 1 Gcd10p family CREPT PF16566.5 CAR25508.1 - 0.13 12.4 1.9 0.27 11.4 1.9 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Methyltr_RsmB-F PF01189.17 CAR25509.1 - 1.2e-81 273.2 0.0 2.5e-81 272.1 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CAR25509.1 - 4.2e-07 30.4 0.0 1.7e-06 28.4 0.0 2.1 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CAR25509.1 - 0.02 15.0 0.0 0.047 13.8 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Actin PF00022.19 CAR25510.1 - 2.1e-52 178.1 0.0 1.2e-48 165.7 0.0 2.6 1 1 0 1 1 1 1 Actin Ras PF00071.22 CAR25511.1 - 9.8e-56 187.8 0.0 1.4e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR25511.1 - 2.3e-22 79.5 0.0 4.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR25511.1 - 4.6e-09 36.0 0.0 7.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CAR25511.1 - 0.00086 18.6 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 CAR25511.1 - 0.00093 18.7 0.0 0.0018 17.7 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CAR25511.1 - 0.0016 18.0 0.2 0.0063 16.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAR25511.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 CAR25511.1 - 0.0062 15.4 0.2 0.021 13.7 0.2 1.8 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 CAR25511.1 - 0.009 16.1 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CAR25511.1 - 0.039 14.5 0.0 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Y_phosphatase2 PF03162.13 CAR25513.1 - 5e-49 166.1 0.0 5.9e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CAR25513.1 - 6.5e-05 23.0 0.0 7.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Aminotran_1_2 PF00155.21 CAR25514.1 - 3e-64 217.5 0.0 3.4e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 CAR25514.1 - 0.00025 20.0 0.0 0.00036 19.5 0.0 1.1 1 0 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.20 CAR25514.1 - 0.11 11.0 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Microcephalin PF12258.8 CAR25514.1 - 0.12 11.5 0.1 0.18 11.0 0.1 1.1 1 0 0 1 1 1 0 Microcephalin protein NUP214 PF16755.5 CAR25515.1 - 1.5e-171 570.5 6.6 2.5e-171 569.8 6.6 1.3 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Porin_3 PF01459.22 CAR25516.1 - 4.8e-66 223.0 1.6 5.3e-66 222.8 1.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin Vac7 PF12751.7 CAR25517.1 - 9.7e-31 107.6 20.6 3.4e-20 72.8 0.0 3.6 3 0 0 3 3 3 2 Vacuolar segregation subunit 7 DSPc PF00782.20 CAR25518.1 - 8.6e-35 119.4 0.0 1.3e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CAR25518.1 - 0.055 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate MR_MLE_C PF13378.6 CAR25518.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Enolase C-terminal domain-like tRNA_SAD PF07973.14 CAR25519.1 - 3.6e-08 33.4 0.1 7.7e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 CAR25519.1 - 2.4e-06 26.3 0.0 3.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) Fip1 PF05182.13 CAR25519.1 - 0.31 10.6 1.4 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Fip1 motif WD40 PF00400.32 CAR25520.1 - 6.8e-08 33.1 1.8 0.0042 17.9 0.3 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR25520.1 - 0.00061 20.0 0.2 2.7 8.4 0.0 3.5 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CAR25521.1 - 1e-37 130.0 0.0 1.9e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25521.1 - 5.7e-27 94.6 0.0 8.5e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR25521.1 - 0.011 14.7 1.1 0.014 14.4 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 CAR25521.1 - 0.068 12.5 0.0 0.17 11.2 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Arb2 PF09757.9 CAR25522.1 - 1.8e-94 315.7 0.0 2.7e-94 315.1 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 CAR25522.1 - 7.1e-89 298.3 0.0 1.1e-88 297.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Methyltr_RsmB-F PF01189.17 CAR25523.1 - 1e-21 77.5 0.0 1.7e-21 76.8 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Iso_dh PF00180.20 CAR25524.1 - 6.1e-108 361.1 0.0 7.4e-108 360.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase R3H PF01424.22 CAR25525.1 - 7.9e-20 70.6 0.1 1.4e-19 69.9 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CAR25525.1 - 5.4e-09 35.9 58.6 2.6e-06 27.4 16.9 12.9 13 0 0 13 13 13 5 NF-X1 type zinc finger YbgS PF13985.6 CAR25525.1 - 1.1 9.6 0.0 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 YbgS-like protein MRP-S25 PF13741.6 CAR25526.1 - 1.5e-93 312.6 3.4 1.8e-93 312.4 3.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 CAR25526.1 - 3.3e-07 30.6 0.5 3.5e-05 24.1 0.0 2.6 2 1 1 3 3 3 2 Mitochondrial ribosomal protein S23 DUF1242 PF06842.12 CAR25527.1 - 6.9e-16 57.8 0.8 9.1e-16 57.4 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) UTP25 PF06862.12 CAR25528.1 - 1.2e-195 650.8 5.9 1.6e-195 650.4 5.9 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 CAR25528.1 - 0.0024 17.6 0.1 0.066 13.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ICE2 PF08426.10 CAR25529.1 - 2e-155 517.9 32.1 2.3e-155 517.7 32.1 1.0 1 0 0 1 1 1 1 ICE2 Cyclin_N PF00134.23 CAR25530.1 - 4.4e-17 62.0 1.5 1.8e-16 60.0 0.2 2.3 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CAR25530.1 - 0.0073 16.7 1.3 0.031 14.6 1.3 2.0 1 1 0 1 1 1 1 Cyclin C-terminal domain Cyclin_C PF02984.19 CAR25530.1 - 0.014 15.4 4.9 1.4 9.0 2.0 3.3 2 1 1 3 3 3 0 Cyclin, C-terminal domain Aa_trans PF01490.18 CAR25531.1 - 3.9e-113 378.2 18.1 4.5e-113 378.0 18.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Evf PF18270.1 CAR25531.1 - 0.012 15.1 0.3 0.02 14.3 0.3 1.3 1 0 0 1 1 1 0 Virulence factor Evf Y_phosphatase2 PF03162.13 CAR25532.1 - 2e-62 209.7 0.0 2.2e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CAR25532.1 - 1.9e-07 31.3 0.0 2e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CAR25532.1 - 0.00091 19.1 0.0 0.00099 18.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR25532.1 - 0.002 17.8 0.0 0.0026 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Aim19 PF10315.9 CAR25533.1 - 1.3e-37 128.6 0.3 1.6e-37 128.3 0.3 1.1 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Histone PF00125.24 CAR25534.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CAR25534.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CAR25534.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CAR25534.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CAR25534.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CAR25534.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CAR25535.1 - 1.8e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CAR25535.1 - 1.4e-05 25.4 0.2 1.7e-05 25.2 0.2 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR25535.1 - 1.9e-05 24.9 0.1 3.2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CAR25535.1 - 2.5e-05 24.4 0.1 3.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CAR25535.1 - 0.00016 22.0 0.1 0.00022 21.6 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CAR25535.1 - 0.0028 17.7 0.0 0.0034 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CAR25535.1 - 0.0093 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CAR25535.1 - 0.049 14.1 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Glyco_transf_15 PF01793.16 CAR25536.1 - 2.5e-83 280.0 16.4 9.5e-55 186.1 7.4 2.1 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Sds3 PF08598.11 CAR25537.1 - 3.8e-76 255.9 7.6 4.7e-76 255.6 7.6 1.1 1 0 0 1 1 1 1 Sds3-like Met_10 PF02475.16 CAR25538.1 - 1.5e-10 41.2 0.0 3.3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 CAR25538.1 - 9.4e-06 25.4 0.0 2.1e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 CAR25538.1 - 0.0065 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain zf-C2H2 PF00096.26 CAR25539.1 - 4.7e-14 52.0 11.2 7.7e-07 29.2 1.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR25539.1 - 8.9e-14 51.2 11.8 8.3e-09 35.5 0.4 3.9 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR25539.1 - 3.7e-10 39.8 10.0 0.00013 22.5 0.9 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CAR25539.1 - 7.8e-07 29.2 3.1 0.024 14.9 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CAR25539.1 - 1.5e-06 28.0 7.9 0.0061 16.5 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CAR25539.1 - 2.4e-06 27.7 2.1 0.0005 20.4 0.2 2.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.6 CAR25539.1 - 0.00051 20.5 5.3 0.0011 19.5 2.2 2.4 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain zf_UBZ PF18439.1 CAR25539.1 - 0.003 17.1 0.7 0.37 10.4 0.3 3.0 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 CAR25539.1 - 0.013 15.3 2.4 1.1 9.0 0.1 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn-ribbon_8 PF09723.10 CAR25539.1 - 0.16 12.1 0.8 0.55 10.4 0.8 2.0 1 1 0 1 1 1 0 Zinc ribbon domain zf-BED PF02892.15 CAR25539.1 - 0.61 10.1 5.4 19 5.4 3.3 3.1 2 1 0 2 2 2 0 BED zinc finger zf-AN1 PF01428.16 CAR25539.1 - 0.9 9.8 4.7 6.8 6.9 1.0 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger Bac_surface_Ag PF01103.23 CAR25540.1 - 2.8e-42 145.3 4.8 3.9e-42 144.9 4.8 1.2 1 0 0 1 1 1 1 Surface antigen Thioredoxin_14 PF18402.1 CAR25540.1 - 0.088 12.7 0.8 0.18 11.7 0.8 1.5 1 1 0 1 1 1 0 Thioredoxin-like domain DFP PF04127.15 CAR25541.1 - 3.3e-15 56.4 0.0 3.7e-06 26.9 0.0 2.7 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Ubiquitin_3 PF14836.6 CAR25541.1 - 0.13 12.3 0.0 13 5.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain RRM_1 PF00076.22 CAR25542.1 - 9.4e-54 179.1 0.4 2.9e-19 68.7 0.3 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR25542.1 - 1.6e-09 37.4 0.0 0.00012 21.7 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR25542.1 - 1.8e-08 34.1 0.0 0.00046 20.0 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CAR25542.1 - 0.0016 18.4 0.2 0.057 13.4 0.1 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CAR25542.1 - 0.0035 17.4 0.1 0.37 10.9 0.0 3.4 3 1 0 3 3 3 1 RNA recognition motif PHM7_cyt PF14703.6 CAR25542.1 - 0.0038 17.5 0.0 3.7 7.7 0.0 3.0 3 0 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter Cas_Cas2CT1978 PF09707.10 CAR25542.1 - 0.026 14.6 0.1 4.6 7.4 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) DUF3421 PF11901.8 CAR25542.1 - 0.12 12.4 0.2 3 7.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3421) RRM_8 PF11835.8 CAR25542.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain DbpA PF03880.15 CAR25542.1 - 0.14 12.2 0.2 24 5.0 0.0 2.6 2 0 0 2 2 2 0 DbpA RNA binding domain UCH PF00443.29 CAR25543.1 - 7.1e-47 160.1 0.2 1.2e-46 159.4 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR25543.1 - 1.8e-06 27.8 5.2 5.3e-05 23.0 5.2 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TraI_2_C PF07515.11 CAR25543.1 - 0.021 14.8 0.0 0.078 12.9 0.0 1.9 1 0 0 1 1 1 0 Putative conjugal transfer nickase/helicase TraI C-term FAST_1 PF06743.15 CAR25543.1 - 0.16 12.0 0.1 2 8.4 0.0 2.6 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 DUF4614 PF15391.6 CAR25543.1 - 5.6 6.9 0.0 5.6 6.9 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4614) Frataxin_Cyay PF01491.16 CAR25545.1 - 2.6e-36 124.0 0.1 3.4e-36 123.6 0.1 1.1 1 0 0 1 1 1 1 Frataxin-like domain RTBV_P46 PF06216.11 CAR25545.1 - 0.087 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Glyco_hydro_38N PF01074.22 CAR25546.1 - 8.6e-81 271.5 1.1 1.4e-80 270.7 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CAR25546.1 - 1.6e-51 175.4 0.5 1.6e-51 175.4 0.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CAR25546.1 - 1.4e-26 92.5 0.0 3.5e-26 91.2 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CAR25546.1 - 8.7e-10 38.6 0.2 5.1e-09 36.1 0.2 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 CAR25546.1 - 0.0015 17.8 0.0 0.0049 16.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Prenyltrans PF00432.21 CAR25547.1 - 1.5e-31 107.8 0.2 1.4e-07 31.1 0.0 6.1 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CAR25547.1 - 0.00084 18.5 0.0 0.0029 16.8 0.0 1.9 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Mito_carr PF00153.27 CAR25548.1 - 4.1e-46 154.9 5.3 7.5e-18 64.2 0.1 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Tn7_Tnp_TnsA_C PF08721.11 CAR25548.1 - 0.11 13.2 0.1 0.56 10.9 0.0 2.1 2 0 0 2 2 2 0 TnsA endonuclease C terminal ACPS PF01648.20 CAR25549.1 - 2.8e-10 40.3 0.0 5.3e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Pex14_N PF04695.13 CAR25550.1 - 4.7e-30 105.3 5.4 4.7e-30 105.3 5.4 3.6 2 2 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5446 PF17522.2 CAR25550.1 - 0.34 11.1 8.4 0.25 11.5 3.4 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5446) CCDC-167 PF15188.6 CAR25550.1 - 6.1 7.3 11.1 6.4 7.2 0.7 3.2 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 Med5 PF08689.10 CAR25551.1 - 0 1511.2 53.9 0 1511.1 53.9 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 AFP_2 PF18815.1 CAR25551.1 - 0.47 10.8 2.8 1.7 9.0 0.1 3.2 3 0 0 3 3 3 0 Bacterial antifreeze protein repeat SNF2_N PF00176.23 CAR25552.1 - 4e-67 226.4 1.1 4e-67 226.4 1.1 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 CAR25552.1 - 3.8e-48 163.3 19.9 3.8e-48 163.3 19.9 3.5 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 CAR25552.1 - 4e-18 65.8 0.8 5.9e-17 62.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR25552.1 - 2.2e-07 31.1 1.6 1.4e-06 28.5 0.0 3.0 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Fe_hyd_lg_C PF02906.14 CAR25552.1 - 0.028 14.1 4.4 0.08 12.6 4.4 1.7 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Asp_Glu_race PF01177.22 CAR25552.1 - 0.035 13.9 0.5 0.7 9.7 0.7 2.5 2 0 0 2 2 2 0 Asp/Glu/Hydantoin racemase Chorismate_synt PF01264.21 CAR25553.1 - 1.1e-138 461.4 0.1 1.3e-138 461.2 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase SH3_1 PF00018.28 CAR25554.1 - 3e-05 23.5 0.2 0.00012 21.6 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CAR25554.1 - 8.7e-05 22.3 0.1 0.00019 21.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR25554.1 - 0.00013 21.6 0.1 0.00028 20.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core PF01841.19 CAR25554.1 - 0.00013 22.4 0.0 0.00029 21.2 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Nup84_Nup100 PF04121.13 CAR25555.1 - 9.7e-185 615.8 11.3 1.2e-184 615.4 11.3 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Nup96 PF12110.8 CAR25555.1 - 0.096 11.8 0.1 0.54 9.3 0.0 2.1 2 0 0 2 2 2 0 Nuclear protein 96 SUV3_C PF12513.8 CAR25556.1 - 4.2e-15 55.4 1.9 1.1e-14 54.1 1.7 1.9 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CAR25556.1 - 1.6e-12 47.8 0.0 3.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Thiolase_N PF00108.23 CAR25557.1 - 2.1e-93 312.4 0.6 2.7e-93 312.1 0.6 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CAR25557.1 - 3.4e-45 152.6 2.7 5.3e-45 152.0 0.2 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CAR25557.1 - 9.7e-05 22.1 0.7 9.7e-05 22.1 0.7 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain APS_kinase PF01583.20 CAR25558.1 - 4.3e-09 36.5 0.0 5.3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 CAR25558.1 - 1.1e-06 29.2 0.1 3e-06 27.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 CAR25558.1 - 1.3e-05 25.4 0.0 1.7e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase dNK PF01712.19 CAR25558.1 - 0.00077 19.4 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase ABC_tran PF00005.27 CAR25558.1 - 0.0024 18.4 0.0 0.0029 18.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 CAR25558.1 - 0.0035 16.6 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin RsgA_GTPase PF03193.16 CAR25558.1 - 0.0077 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase DUF815 PF05673.13 CAR25558.1 - 0.0078 15.4 0.0 0.58 9.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CAR25558.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAR25558.1 - 0.013 15.7 0.0 0.016 15.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 CAR25558.1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA PF00004.29 CAR25558.1 - 0.019 15.4 0.1 0.24 11.8 0.0 2.4 2 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAR25558.1 - 0.022 15.2 0.0 0.055 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 CAR25558.1 - 0.053 13.2 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CAR25558.1 - 0.055 13.7 0.0 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CAR25558.1 - 0.056 12.7 0.0 0.52 9.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 CAR25558.1 - 0.067 12.9 0.0 0.09 12.5 0.0 1.4 1 1 0 1 1 1 0 Cytidylate kinase Guanylate_kin PF00625.21 CAR25558.1 - 0.08 12.6 0.0 0.48 10.1 0.0 2.0 2 1 0 2 2 2 0 Guanylate kinase T2SSE PF00437.20 CAR25558.1 - 0.087 11.9 0.0 0.21 10.6 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 CAR25558.1 - 0.15 11.8 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CAR25558.1 - 0.15 12.4 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 CAR25558.1 - 0.2 11.2 0.2 0.39 10.3 0.2 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 CAR25559.1 - 7.1e-47 160.0 0.7 2.7e-41 141.7 0.2 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25559.1 - 6.9e-25 87.8 0.5 2.1e-22 79.7 0.1 2.3 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CAR25559.1 - 4.7e-08 32.7 0.0 6.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CAR25559.1 - 0.00032 20.4 0.2 0.27 10.8 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CAR25559.1 - 0.014 15.3 0.1 0.024 14.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIP49_C PF12260.8 CAR25559.1 - 0.069 12.8 1.1 0.95 9.1 0.2 2.2 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Sybindin PF04099.12 CAR25560.1 - 1.4e-34 119.1 4.9 9.3e-22 77.5 2.4 3.0 2 1 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.13 CAR25560.1 - 5.1e-10 39.6 0.6 1.3e-09 38.2 0.6 1.7 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region RMI1_N PF08585.12 CAR25561.1 - 4.3e-18 65.9 0.0 5.9e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 RecQ mediated genome instability protein MTHFR PF02219.17 CAR25562.1 - 1.8e-107 358.9 0.0 3.3e-107 358.1 0.0 1.4 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ERCC4 PF02732.15 CAR25563.1 - 1.3e-25 90.4 0.5 8.1e-25 87.8 0.0 2.7 3 0 0 3 3 3 1 ERCC4 domain ARID PF01388.21 CAR25564.1 - 5.8e-16 58.9 0.1 5.8e-16 58.9 0.1 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain TFIIA PF03153.13 CAR25564.1 - 0.01 15.8 100.4 0.067 13.2 41.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Myf5 PF12232.8 CAR25564.1 - 0.024 15.4 0.0 0.26 12.1 0.0 2.9 1 0 0 1 1 1 0 Myogenic determination factor 5 BOF PF04076.13 CAR25564.1 - 0.078 13.0 0.2 0.27 11.3 0.2 1.9 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein Glyco_transf_34 PF05637.12 CAR25565.1 - 1.7e-74 250.6 0.4 2.2e-74 250.2 0.4 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 CAR25565.1 - 0.034 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase TPR_1 PF00515.28 CAR25566.1 - 5.1e-18 64.1 1.1 4.4e-06 26.3 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR25566.1 - 5.8e-17 60.4 1.7 0.00042 20.2 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CAR25566.1 - 9.5e-16 57.2 1.3 6.7e-06 25.7 0.1 5.7 4 1 2 6 6 6 3 TPR repeat TPR_14 PF13428.6 CAR25566.1 - 2.2e-13 49.8 0.4 0.0012 19.5 0.2 5.0 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 CAR25566.1 - 3.4e-11 43.5 2.9 0.003 18.0 0.1 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAR25566.1 - 5.2e-11 43.0 1.1 0.0002 21.9 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR25566.1 - 2.5e-10 40.0 1.0 0.66 10.5 0.0 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CAR25566.1 - 7e-09 35.7 0.6 0.00013 22.0 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAR25566.1 - 7.4e-09 35.1 4.2 0.098 12.9 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 CAR25566.1 - 8.2e-07 29.3 6.7 0.02 15.2 0.0 4.5 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAR25566.1 - 8.4e-05 22.8 4.3 0.0022 18.2 1.3 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR25566.1 - 0.00025 21.2 1.9 0.0036 17.5 0.2 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CAR25566.1 - 0.00038 19.8 0.6 0.07 12.3 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAR25566.1 - 0.074 13.1 0.6 10 6.4 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TFIIA PF03153.13 CAR25566.1 - 1.1 9.2 30.0 1.3 8.9 30.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NRN1 PF15056.6 CAR25566.1 - 2.8 8.1 5.7 8 6.6 0.9 3.1 2 1 1 3 3 2 0 Neuritin protein family DEAD PF00270.29 CAR25567.1 - 2.2e-45 154.6 0.6 3.1e-43 147.6 0.1 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR25567.1 - 1.5e-28 99.3 0.2 8.5e-28 96.9 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR25567.1 - 3.3e-06 27.2 2.6 9.9e-06 25.7 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CAR25567.1 - 0.0039 16.6 0.1 0.01 15.2 0.0 1.7 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CAR25567.1 - 0.077 13.3 0.2 0.86 9.9 0.0 2.8 3 1 0 3 3 3 0 AAA domain RNA_pol_Rpb1_4 PF05000.17 CAR25567.1 - 0.22 11.5 0.9 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 4 Torus PF16131.5 CAR25568.1 - 4.5e-35 120.6 0.1 4.5e-35 120.6 0.1 2.0 2 1 0 2 2 2 1 Torus domain RRM_1 PF00076.22 CAR25568.1 - 0.007 16.2 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR25568.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf_CCCH_4 PF18345.1 CAR25568.1 - 1.1 9.4 9.1 0.59 10.3 6.5 1.9 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 CAR25568.1 - 3.5 7.5 7.7 6.7 6.6 7.7 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger PRP1_N PF06424.12 CAR25569.1 - 1.7e-23 83.7 16.8 1.1e-16 61.6 3.3 2.9 2 1 1 3 3 3 2 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 CAR25569.1 - 4.2e-20 72.0 8.9 0.00029 21.3 0.7 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CAR25569.1 - 8e-18 63.6 13.6 0.06 14.2 0.1 10.8 7 3 5 12 12 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAR25569.1 - 2.2e-12 46.1 8.3 0.14 12.3 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 CAR25569.1 - 3.3e-11 43.6 0.1 0.54 11.0 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAR25569.1 - 1.2e-10 40.7 1.4 0.0074 16.4 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAR25569.1 - 5.8e-08 32.9 7.6 1.9 8.9 0.0 7.1 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAR25569.1 - 6.9e-08 32.4 2.0 0.66 10.5 0.0 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAR25569.1 - 6.3e-07 28.9 2.6 0.11 12.3 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR25569.1 - 4.3e-06 26.9 6.8 0.49 10.6 0.0 6.0 5 1 3 8 8 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CAR25569.1 - 6.6e-05 23.0 0.5 0.32 11.2 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAR25569.1 - 0.0012 19.4 11.0 10 7.0 0.1 7.7 10 0 0 10 10 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAR25569.1 - 0.0065 16.4 1.4 52 4.2 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CAR25569.1 - 0.0095 15.6 0.3 6.9 6.4 0.0 3.8 4 1 0 4 4 3 1 TPR repeat ChAPs PF09295.10 CAR25569.1 - 0.049 12.6 4.9 0.21 10.5 0.2 2.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) SPO22 PF08631.10 CAR25569.1 - 0.092 12.2 12.2 0.99 8.8 0.0 3.8 3 2 1 5 5 5 0 Meiosis protein SPO22/ZIP4 like TPR_4 PF07721.14 CAR25569.1 - 0.18 12.6 0.2 16 6.5 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HEPN PF05168.14 CAR25569.1 - 1.9 8.7 7.0 1.8 8.7 0.1 4.0 5 0 0 5 5 5 0 HEPN domain Fungal_trans_2 PF11951.8 CAR25570.1 - 2.2e-26 92.6 0.2 3.2e-26 92.1 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR25570.1 - 3.6e-07 30.2 12.4 6.1e-07 29.5 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arginase PF00491.21 CAR25571.1 - 4.4e-82 275.7 0.0 5.4e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 Arginase family MatE PF01554.18 CAR25572.1 - 3.5e-52 176.3 31.7 1.7e-37 128.5 11.5 2.6 3 0 0 3 3 3 2 MatE Mal_decarbox_Al PF16957.5 CAR25572.1 - 0.1 10.9 0.0 0.2 9.9 0.0 1.4 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter FMN_red PF03358.15 CAR25573.1 - 2.1e-09 37.3 0.0 2.8e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase SGL PF08450.12 CAR25574.1 - 8.7e-40 136.8 0.0 1.1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Bac_rhodopsin PF01036.18 CAR25575.1 - 5.3e-36 124.3 21.6 6.7e-36 123.9 21.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1772 PF08592.11 CAR25575.1 - 8.5 6.7 9.0 7 7.0 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) FMN_red PF03358.15 CAR25576.1 - 6.6e-09 35.7 0.0 8.9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CAR25576.1 - 0.0031 17.2 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold CX9C PF16860.5 CAR25577.1 - 1.7e-27 95.1 13.2 3.9e-19 68.4 3.5 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CAR25577.1 - 1.7e-07 31.2 12.0 0.0011 19.0 0.9 2.3 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.10 CAR25577.1 - 4.7e-05 23.3 10.1 5.3e-05 23.2 1.4 2.2 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.12 CAR25577.1 - 8.3e-05 22.8 7.7 0.017 15.3 0.6 3.5 1 1 3 4 4 4 2 Uncharacterised protein family (UPF0203) Pet191_N PF10203.9 CAR25577.1 - 0.0035 17.6 11.5 0.0061 16.8 7.0 2.8 1 1 1 2 2 2 1 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.13 CAR25577.1 - 0.0085 15.8 8.1 0.15 11.8 0.6 2.6 1 1 2 3 3 3 3 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) DB PF01682.19 CAR25577.1 - 0.03 14.6 9.8 0.063 13.6 9.8 1.6 1 1 0 1 1 1 0 DB module DUF244 PF03112.14 CAR25577.1 - 0.044 13.6 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF GCK PF07802.11 CAR25577.1 - 0.1 13.1 7.9 2.7 8.4 0.6 2.4 1 1 0 2 2 2 0 GCK domain COX6B PF02297.17 CAR25577.1 - 0.14 12.4 9.8 0.46 10.8 7.0 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb WD40 PF00400.32 CAR25578.1 - 5e-10 39.8 12.1 0.011 16.6 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR25578.1 - 1.9e-07 31.3 0.2 0.18 12.2 0.1 5.1 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1752 PF08550.10 CAR25579.1 - 3.1e-12 46.1 3.2 7.4e-12 44.9 3.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Myb_DNA-binding PF00249.31 CAR25581.1 - 7.1e-20 70.9 18.1 7e-11 42.1 0.4 4.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR25581.1 - 4.9e-17 61.9 12.6 4.7e-14 52.4 0.7 4.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 CAR25581.1 - 0.43 10.9 9.5 1.7 9.0 0.4 4.0 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.6 CAR25581.1 - 3.2 8.2 17.2 1.8 9.0 6.6 4.4 3 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain Ribosomal_S17_N PF16205.5 CAR25582.1 - 6.1e-32 109.8 1.1 1.2e-31 108.9 1.1 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CAR25582.1 - 5e-26 90.6 3.7 5e-26 90.6 3.7 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 FMP23 PF17315.2 CAR25583.1 - 7.4e-79 263.2 0.6 8.7e-79 262.9 0.6 1.0 1 0 0 1 1 1 1 Found in mitochondrial proteome ADH_zinc_N PF00107.26 CAR25584.1 - 9.8e-25 87.0 0.0 1.7e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR25584.1 - 4.3e-20 73.1 0.0 3.7e-19 70.1 0.0 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR25584.1 - 8e-08 32.1 0.0 1.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CAR25584.1 - 0.028 14.3 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Semialdhyde_dh PF01118.24 CAR25584.1 - 0.086 13.3 0.1 0.16 12.4 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain tRNA-synt_2b PF00587.25 CAR25586.1 - 2.6e-31 108.9 0.0 4.5e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CAR25586.1 - 1.7e-22 79.7 9.2 1.7e-22 79.7 9.2 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain MAP7 PF05672.11 CAR25586.1 - 0.0026 17.4 0.2 0.0041 16.8 0.2 1.3 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family Atg31 PF09795.9 CAR25587.1 - 9.7e-60 201.1 4.0 1.1e-59 200.9 4.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 31 DEAD PF00270.29 CAR25588.1 - 1e-42 145.9 0.8 1.7e-42 145.2 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR25588.1 - 6.2e-33 113.5 0.2 2.2e-31 108.5 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR25588.1 - 7.7e-05 22.8 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAR25588.1 - 0.0023 18.2 0.3 0.0063 16.8 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR25588.1 - 0.0023 17.7 0.4 0.0056 16.4 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR25588.1 - 0.004 17.5 0.2 0.034 14.5 0.2 2.2 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 CAR25588.1 - 0.0049 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit PhoH PF02562.16 CAR25588.1 - 0.012 15.1 1.4 0.16 11.4 1.4 2.3 1 1 0 1 1 1 0 PhoH-like protein Helicase_RecD PF05127.14 CAR25588.1 - 0.016 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Helicase tRNA-synt_1b PF00579.25 CAR25588.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) PRK PF00485.18 CAR25589.1 - 2.3e-11 43.8 0.1 3.1e-11 43.4 0.1 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family BRCC36_C PF18110.1 CAR25590.1 - 0.026 14.6 0.4 2.2 8.5 0.0 3.3 3 0 0 3 3 3 0 BRCC36 C-terminal helical domain ACT_6 PF13740.6 CAR25590.1 - 0.043 13.8 0.2 0.32 11.0 0.0 2.6 4 0 0 4 4 4 0 ACT domain GCV_T PF01571.21 CAR25591.1 - 3.3e-85 285.5 0.0 4.1e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CAR25591.1 - 2.2e-13 49.9 0.0 6.1e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 CAR25591.1 - 0.041 14.0 0.0 0.68 10.1 0.0 2.2 1 1 0 2 2 2 0 Sarcosine oxidase, gamma subunit family MFS_1 PF07690.16 CAR25592.1 - 5.5e-29 101.2 23.1 5.5e-29 101.2 23.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR25592.1 - 1.2e-07 31.0 1.4 1.2e-07 31.0 1.4 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter Acyltransferase PF01553.21 CAR25593.1 - 2.7e-30 104.8 0.0 4.2e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CAR25593.1 - 2.7e-15 56.2 0.1 5.6e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus AMP-binding PF00501.28 CAR25594.1 - 5.4e-58 196.6 0.0 6.8e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAR25594.1 - 1.5e-05 25.9 0.0 2.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fig1 PF12351.8 CAR25595.1 - 8.1e-61 205.2 2.7 8.1e-61 205.2 2.7 1.5 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 DctQ PF04290.12 CAR25595.1 - 0.16 11.9 11.0 0.38 10.7 5.0 2.8 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component ATP-synt PF00231.19 CAR25596.1 - 2.6e-71 240.6 2.4 2.9e-71 240.4 2.4 1.0 1 0 0 1 1 1 1 ATP synthase Spore_YhcN_YlaJ PF09580.10 CAR25596.1 - 0.0079 16.3 0.1 0.0079 16.3 0.1 1.9 3 0 0 3 3 3 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) IPK PF03770.16 CAR25597.1 - 2.9e-47 161.1 0.0 2.9e-47 161.1 0.0 3.0 3 0 0 3 3 3 1 Inositol polyphosphate kinase PCYCGC PF13798.6 CAR25597.1 - 2.8 7.8 0.0 2.8 7.8 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function with PCYCGC motif DASH_Dad1 PF08649.10 CAR25598.1 - 1.5e-26 92.3 1.6 1.9e-26 92.0 1.6 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 GCR1_C PF12550.8 CAR25598.1 - 0.063 13.6 0.0 0.28 11.5 0.0 1.8 1 1 1 2 2 2 0 Transcriptional activator of glycolytic enzymes PNP_phzG_C PF10590.9 CAR25600.1 - 1.8e-20 72.7 3.7 3.6e-20 71.8 3.7 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 CAR25600.1 - 2e-11 43.9 0.0 3.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 CAR25600.1 - 0.079 13.6 0.1 0.17 12.5 0.1 1.7 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Wap1 PF16997.5 CAR25601.1 - 4.1e-125 417.9 7.1 6.4e-125 417.3 7.1 1.3 1 0 0 1 1 1 1 Wap1 domain Sld5 PF05916.11 CAR25602.1 - 1.5e-09 38.2 0.6 2.5e-09 37.5 0.6 1.4 1 0 0 1 1 1 1 GINS complex protein PIF1 PF05970.14 CAR25602.1 - 0.0026 17.0 0.0 0.0055 15.9 0.0 1.4 1 1 0 1 1 1 1 PIF1-like helicase DUF4062 PF13271.6 CAR25602.1 - 0.13 12.6 0.1 0.5 10.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4062) SLD5_C PF16922.5 CAR25602.1 - 0.16 12.2 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 DNA replication complex GINS protein SLD5 C-terminus Methyltransf_25 PF13649.6 CAR25603.1 - 6.2e-12 46.1 0.1 9.1e-11 42.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CAR25603.1 - 3.7e-11 43.0 0.0 6.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 CAR25603.1 - 3.1e-09 37.3 0.0 6.8e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR25603.1 - 3.4e-09 36.7 0.0 7.9e-09 35.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR25603.1 - 9.6e-08 32.0 0.0 1.3e-07 31.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CAR25603.1 - 1.5e-06 27.4 0.1 1.9e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 CAR25603.1 - 1.4e-05 24.5 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CAR25603.1 - 0.00022 20.8 0.1 0.00045 19.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CAR25603.1 - 0.0014 19.3 0.0 0.0031 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CAR25603.1 - 0.0022 17.9 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CAR25603.1 - 0.0025 17.6 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 CAR25603.1 - 0.0054 16.9 0.0 0.012 15.8 0.0 1.5 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 CAR25603.1 - 0.024 14.6 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CAR25603.1 - 0.045 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.16 CAR25603.1 - 0.047 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase DOT1 PF08123.13 CAR25603.1 - 0.062 12.8 0.8 0.27 10.7 0.2 2.0 1 1 0 2 2 2 0 Histone methylation protein DOT1 Met_10 PF02475.16 CAR25603.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.5 2 0 0 2 2 2 0 Met-10+ like-protein RrnaAD PF00398.20 CAR25603.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ribosomal_L4 PF00573.22 CAR25604.1 - 1.2e-43 149.0 0.6 1.7e-43 148.6 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CAR25604.1 - 8.1e-30 102.7 4.0 1.8e-29 101.6 1.2 2.4 2 1 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain SET PF00856.28 CAR25605.1 - 1.3e-09 38.7 0.1 0.0017 18.8 0.0 3.9 3 1 0 3 3 3 2 SET domain DUF2052 PF09747.9 CAR25605.1 - 0.012 15.8 1.6 0.012 15.8 1.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Na_trans_assoc PF06512.13 CAR25605.1 - 0.027 14.7 7.1 0.79 10.0 1.0 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated NOA36 PF06524.12 CAR25605.1 - 0.22 10.8 12.9 0.42 9.9 12.9 1.3 1 0 0 1 1 1 0 NOA36 protein BUD22 PF09073.10 CAR25605.1 - 0.33 10.3 7.9 0.075 12.4 2.4 1.9 2 0 0 2 2 2 0 BUD22 Cwf_Cwc_15 PF04889.12 CAR25605.1 - 0.5 10.1 13.7 0.09 12.5 7.1 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FYDLN_acid PF09538.10 CAR25605.1 - 0.59 10.8 14.0 0.16 12.6 5.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Sigma70_ner PF04546.13 CAR25605.1 - 0.63 9.9 9.8 0.18 11.6 4.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.12 CAR25605.1 - 0.9 8.9 15.9 0.042 13.3 7.5 2.0 2 0 0 2 2 2 0 SDA1 RXT2_N PF08595.11 CAR25605.1 - 1.3 9.0 9.0 0.037 14.0 2.5 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Eapp_C PF10238.9 CAR25605.1 - 1.6 8.8 6.8 0.27 11.3 2.4 1.8 2 0 0 2 2 2 0 E2F-associated phosphoprotein RNA_pol_3_Rpc31 PF11705.8 CAR25605.1 - 2.7 8.2 21.3 0.095 12.9 12.8 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 CAR25605.1 - 3.1 7.4 10.6 0.23 11.1 4.1 2.1 2 0 0 2 2 2 0 FAM176 family Afi1 PF07792.12 CAR25605.1 - 4.1 7.9 7.2 0.44 11.0 1.0 2.0 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Cytomega_UL84 PF06284.11 CAR25605.1 - 5.6 5.3 6.5 8 4.8 6.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CTP_transf_1 PF01148.20 CAR25606.1 - 2.2e-79 267.0 17.9 2.9e-79 266.6 17.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF433 PF04255.14 CAR25606.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Pkinase PF00069.25 CAR25607.1 - 2.6e-65 220.4 0.0 3.5e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25607.1 - 4.5e-36 124.5 0.0 6e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CAR25607.1 - 0.0014 19.2 0.8 0.0042 17.7 0.8 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CAR25607.1 - 0.002 17.5 0.0 0.036 13.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CAR25607.1 - 0.0021 18.0 1.7 0.42 10.5 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAR25607.1 - 0.06 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase ADH_zinc_N PF00107.26 CAR25608.1 - 2.4e-09 37.2 0.0 4.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF5614 PF18474.1 CAR25608.1 - 0.016 14.6 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5614) DUF4795 PF16043.5 CAR25608.1 - 0.056 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) CSG2 PF16965.5 CAR25609.1 - 8.9e-164 545.2 6.8 1.1e-163 544.8 6.8 1.1 1 0 0 1 1 1 1 Ceramide synthase regulator YchF-GTPase_C PF06071.13 CAR25610.1 - 2.1e-36 124.0 0.0 5.3e-36 122.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CAR25610.1 - 6.2e-17 61.7 0.0 1.4e-16 60.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR25610.1 - 0.0053 16.3 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 CAR25610.1 - 0.032 14.3 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 TGS domain RSB_motif PF16294.5 CAR25610.1 - 0.16 12.2 0.4 0.51 10.6 0.4 1.8 1 1 0 1 1 1 0 RNSP1-SAP18 binding (RSB) motif SCO1-SenC PF02630.14 CAR25611.1 - 6e-48 162.2 0.0 8.5e-48 161.7 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CAR25611.1 - 0.00048 20.0 0.0 0.0011 18.9 0.0 1.5 1 1 1 2 2 2 1 AhpC/TSA family Chitin_synth_1 PF01644.17 CAR25612.1 - 2.5e-69 232.4 0.2 4e-69 231.8 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 CAR25612.1 - 2.5e-22 79.2 6.6 4.7e-18 65.1 0.0 3.0 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 CAR25612.1 - 1.5e-19 69.7 0.1 4.3e-19 68.2 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 CAR25612.1 - 4.7e-10 39.7 0.4 4.7e-10 39.7 0.4 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CAR25612.1 - 0.0011 19.0 0.0 0.0029 17.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 PMP22_Claudin PF00822.20 CAR25612.1 - 0.023 14.6 3.5 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Peptidase_M20 PF01546.28 CAR25613.1 - 3e-32 112.0 0.0 4.8e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR25613.1 - 1.1e-09 38.1 0.0 5.3e-09 36.0 0.0 2.1 3 0 0 3 3 3 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CAR25613.1 - 6.8e-05 22.7 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Chitin_synth_2 PF03142.15 CAR25614.1 - 5.3e-288 955.9 0.1 8.3e-288 955.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CAR25614.1 - 3.5e-12 46.7 2.8 1.5e-11 44.6 2.8 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CAR25614.1 - 2.1e-11 44.2 0.0 1.8e-08 34.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CAR25614.1 - 0.00084 18.9 0.1 0.0021 17.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CAR25614.1 - 0.0058 16.4 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF1418 PF07214.12 CAR25614.1 - 4.8 7.1 6.7 13 5.7 6.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) Macro PF01661.21 CAR25615.1 - 1.9e-27 95.7 0.0 4.4e-27 94.5 0.0 1.5 1 1 0 1 1 1 1 Macro domain Abhydrolase_1 PF00561.20 CAR25615.1 - 0.14 11.8 0.2 0.29 10.7 0.2 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Transp_cyt_pur PF02133.15 CAR25616.1 - 2.2e-161 537.6 43.3 2.6e-161 537.3 43.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ABC2_membrane PF01061.24 CAR25617.1 - 2.3e-62 210.2 61.3 1.1e-38 132.7 14.5 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CAR25617.1 - 7.6e-37 126.9 0.0 1.4e-19 71.0 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 CAR25617.1 - 2.4e-33 113.9 6.2 1.2e-28 98.9 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CAR25617.1 - 5.3e-08 32.3 39.2 5.6e-07 29.0 13.9 3.4 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 CAR25617.1 - 3.7e-07 30.7 0.1 1e-06 29.2 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CAR25617.1 - 3.3e-05 24.4 0.1 0.0021 18.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAR25617.1 - 3.6e-05 23.7 0.1 0.00029 20.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CAR25617.1 - 0.00079 20.0 0.1 0.0036 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CAR25617.1 - 0.0014 18.3 0.4 0.079 12.7 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CAR25617.1 - 0.0028 17.5 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 CAR25617.1 - 0.0041 17.5 0.1 0.49 10.8 0.0 3.1 3 0 0 3 3 2 1 RNA helicase SMC_N PF02463.19 CAR25617.1 - 0.0063 16.0 0.0 1.1 8.6 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CAR25617.1 - 0.0066 16.7 0.9 0.015 15.5 0.1 2.0 2 0 0 2 2 1 1 AAA domain RecT PF03837.14 CAR25617.1 - 0.0085 15.6 0.3 0.22 11.0 0.0 2.3 2 0 0 2 2 2 1 RecT family AAA_25 PF13481.6 CAR25617.1 - 0.015 14.9 0.1 0.046 13.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CAR25617.1 - 0.016 14.8 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CAR25617.1 - 0.037 13.7 0.1 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CAR25617.1 - 0.038 14.1 1.4 0.26 11.4 0.3 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 CAR25617.1 - 0.045 13.7 0.9 0.24 11.3 0.1 2.5 3 0 0 3 3 2 0 NACHT domain TsaE PF02367.17 CAR25617.1 - 0.07 13.1 0.3 0.2 11.6 0.3 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CAR25617.1 - 0.12 12.6 0.1 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CAR25617.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CAR25617.1 - 0.46 10.2 1.6 2.9 7.6 0.4 2.4 2 0 0 2 2 2 0 AAA domain GalKase_gal_bdg PF10509.9 CAR25618.1 - 2e-21 75.2 0.0 4e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CAR25618.1 - 5.1e-14 52.3 0.5 1.1e-13 51.2 0.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CAR25618.1 - 1.9e-13 50.6 0.0 4.1e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal DUF1748 PF08520.10 CAR25618.1 - 0.02 14.8 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Aldose_epim PF01263.20 CAR25619.1 - 6.9e-58 196.3 0.0 1.2e-57 195.5 0.0 1.4 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.21 CAR25619.1 - 1.1e-55 188.7 0.0 2.1e-55 187.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAR25619.1 - 4e-55 187.5 0.0 5.7e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CAR25619.1 - 2.7e-16 59.4 0.0 7.7e-16 57.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CAR25619.1 - 2.9e-14 52.9 0.0 8.3e-12 44.8 0.1 2.3 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CAR25619.1 - 1.3e-08 34.3 0.0 2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 CAR25619.1 - 3.2e-08 33.7 0.1 1.1e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.12 CAR25619.1 - 1e-07 31.4 0.0 8.1e-06 25.2 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CAR25619.1 - 6e-06 25.8 0.0 9.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 CAR25619.1 - 0.00091 19.2 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding GalP_UDP_transf PF01087.22 CAR25620.1 - 1.1e-65 221.5 0.0 3.2e-65 220.0 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 CAR25620.1 - 1.5e-62 210.2 0.1 2.6e-62 209.4 0.1 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 CAR25620.1 - 0.0065 15.3 0.1 0.54 9.0 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4921) HIT PF01230.23 CAR25620.1 - 0.019 15.7 0.0 0.68 10.7 0.0 2.4 2 0 0 2 2 2 0 HIT domain WG_beta_rep PF14903.6 CAR25620.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 WG containing repeat AAA PF00004.29 CAR25621.1 - 4e-40 137.3 0.0 6.8e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR25621.1 - 1.3e-10 40.9 0.3 2.8e-10 39.8 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CAR25621.1 - 2.2e-08 33.9 0.0 4.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CAR25621.1 - 3e-06 27.4 0.0 7.1e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CAR25621.1 - 1.6e-05 25.2 0.2 0.0077 16.5 0.2 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CAR25621.1 - 2.1e-05 23.9 0.0 3.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CAR25621.1 - 5.5e-05 23.2 0.2 0.00028 20.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAR25621.1 - 0.00012 22.6 0.1 0.0037 17.7 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CAR25621.1 - 0.00076 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CAR25621.1 - 0.0033 17.7 0.3 0.0073 16.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 CAR25621.1 - 0.0033 18.0 0.2 0.024 15.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR25621.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CAR25621.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CAR25621.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CAR25621.1 - 0.017 14.9 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 CAR25621.1 - 0.025 13.8 0.0 0.048 12.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 CAR25621.1 - 0.027 13.8 0.1 0.44 9.9 0.1 2.3 1 1 0 2 2 2 0 KaiC NTPase_1 PF03266.15 CAR25621.1 - 0.04 13.8 0.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 CAR25621.1 - 0.044 14.2 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 CAR25621.1 - 0.052 13.1 2.6 0.27 10.8 0.2 2.7 2 1 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 CAR25621.1 - 0.053 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CAR25621.1 - 0.062 12.5 0.1 0.67 9.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain PhoH PF02562.16 CAR25621.1 - 0.074 12.5 0.2 0.5 9.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 CAR25621.1 - 0.099 12.6 0.1 0.6 10.0 0.1 2.1 1 1 1 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 CAR25621.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 CAR25621.1 - 0.16 11.7 1.3 0.29 10.8 0.3 2.1 2 1 0 2 2 2 0 AAA domain PP2C PF00481.21 CAR25622.1 - 3.3e-74 249.8 0.4 5.1e-74 249.2 0.4 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CAR25622.1 - 0.0089 16.0 0.5 0.12 12.3 0.5 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Nitrate_red_del PF02613.15 CAR25622.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Nitrate reductase delta subunit Med2 PF11214.8 CAR25623.1 - 1.7e-33 114.7 32.9 5.6e-30 103.4 32.9 2.6 1 1 0 1 1 1 1 Mediator complex subunit 2 Spem1 PF15670.5 CAR25623.1 - 0.00035 20.2 4.2 0.00044 19.9 4.2 1.2 1 0 0 1 1 1 1 Spermatid maturation protein 1 DDHD PF02862.17 CAR25623.1 - 0.026 14.7 2.5 0.034 14.3 2.5 1.3 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 CAR25623.1 - 0.07 11.4 14.8 0.086 11.1 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Dynamin_N PF00350.23 CAR25623.1 - 0.16 12.1 3.4 0.25 11.4 3.4 1.3 1 0 0 1 1 1 0 Dynamin family Merozoite_SPAM PF07133.11 CAR25623.1 - 0.17 11.8 20.4 0.27 11.2 20.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) NARP1 PF12569.8 CAR25623.1 - 0.29 10.0 13.9 0.39 9.6 13.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 CAR25623.1 - 0.3 10.9 14.1 0.43 10.3 14.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CobT PF06213.12 CAR25623.1 - 0.3 10.4 18.3 0.43 9.9 18.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 CAR25623.1 - 0.35 9.8 7.1 0.55 9.1 7.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CAR25623.1 - 0.41 9.4 11.0 0.48 9.1 11.0 1.1 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 CAR25623.1 - 0.46 10.2 13.4 0.7 9.6 13.4 1.2 1 0 0 1 1 1 0 AAA domain TERB2 PF15101.6 CAR25623.1 - 0.71 9.9 7.2 1.1 9.2 7.2 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NPR3 PF03666.13 CAR25623.1 - 1 8.1 11.8 1.4 7.7 11.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Borrelia_P83 PF05262.11 CAR25623.1 - 1.1 7.7 16.5 1.4 7.3 16.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein VIR_N PF15912.5 CAR25623.1 - 2.2 7.8 10.2 3.2 7.3 10.2 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Zip PF02535.22 CAR25623.1 - 2.5 7.2 5.7 3.1 6.9 5.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM60A PF15396.6 CAR25623.1 - 2.8 7.9 8.9 4 7.4 8.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Hid1 PF12722.7 CAR25623.1 - 2.9 5.9 10.6 3.3 5.7 10.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MDM10 PF12519.8 CAR25623.1 - 3.2 6.5 8.3 4.3 6.1 8.3 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF1682 PF07946.14 CAR25623.1 - 3.2 6.9 22.1 4.1 6.5 22.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Neur_chan_memb PF02932.16 CAR25623.1 - 3.5 7.6 8.1 5.2 7.1 8.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cytochrom_NNT PF03264.14 CAR25623.1 - 3.5 7.3 9.5 5.2 6.7 9.5 1.2 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region ALMT PF11744.8 CAR25623.1 - 7.5 5.3 11.2 9.8 4.9 11.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Paramyxo_ncap PF00973.19 CAR25623.1 - 8.1 5.2 8.1 10 4.9 8.1 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein V_ATPase_I PF01496.19 CAR25623.1 - 9.7 4.0 11.4 12 3.6 11.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP-synt_DE_N PF02823.16 CAR25625.1 - 6.7e-17 61.2 0.0 1.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Rad21_Rec8_N PF04825.13 CAR25626.1 - 7.4e-24 84.0 0.2 2.1e-23 82.6 0.2 1.7 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CAR25626.1 - 1.7e-11 43.2 0.0 4.5e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DRIM PF07539.12 CAR25627.1 - 1.5e-160 535.6 0.6 1.5e-160 535.6 0.6 4.1 5 1 1 6 6 6 1 Down-regulated in metastasis IFRD PF05004.13 CAR25627.1 - 0.0037 16.4 7.5 0.35 9.9 0.1 4.7 4 1 1 5 5 5 2 Interferon-related developmental regulator (IFRD) YtzH PF14165.6 CAR25627.1 - 0.16 12.4 5.5 1.5 9.3 0.3 4.2 3 0 0 3 3 3 0 YtzH-like protein HEAT PF02985.22 CAR25627.1 - 0.45 10.9 3.9 1.2e+02 3.4 0.1 5.7 5 0 0 5 5 5 0 HEAT repeat HMG_box PF00505.19 CAR25628.1 - 8.5e-16 58.1 2.8 2.5e-15 56.6 2.8 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CAR25628.1 - 2.1e-14 53.8 3.1 6.4e-14 52.3 3.1 1.9 1 0 0 1 1 1 1 HMG-box domain FTCD_C PF04961.12 CAR25628.1 - 0.11 12.3 1.3 0.19 11.5 1.3 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase YqzL PF14006.6 CAR25628.1 - 1 9.7 0.1 1 9.7 0.1 4.5 4 2 1 5 5 5 0 YqzL-like protein DUF155 PF02582.14 CAR25629.1 - 2.7e-56 190.4 1.3 4.3e-56 189.8 1.3 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 CAR25629.1 - 0.022 15.2 0.0 0.06 13.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Histone_H2A_C PF16211.5 CAR25630.1 - 6.7e-21 73.7 1.8 1.1e-20 73.0 1.8 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAR25630.1 - 8.6e-18 65.0 0.0 1.2e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR25630.1 - 1.8e-06 28.1 0.0 2.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CAR25631.1 - 3e-19 69.7 4.1 3.7e-19 69.4 4.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR25631.1 - 4e-05 23.8 0.1 4e-05 23.8 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CAR25631.1 - 0.0043 17.5 0.0 0.0075 16.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 CAR25631.1 - 0.061 13.4 0.8 0.075 13.1 0.8 1.1 1 0 0 1 1 1 0 YscO-like protein Thiamine_BP PF01910.17 CAR25632.1 - 1.4e-28 98.6 0.0 1.6e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Hom_end PF05204.14 CAR25633.1 - 0.13 12.4 0.1 0.35 11.1 0.1 1.8 1 1 0 1 1 1 0 Homing endonuclease BRICHOS PF04089.14 CAR25634.1 - 0.079 13.2 0.1 0.22 11.8 0.1 1.8 1 0 0 1 1 1 0 BRICHOS domain Trehalase PF01204.18 CAR25635.1 - 2.6e-184 613.8 0.0 3.2e-184 613.5 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CAR25635.1 - 4.2e-16 58.4 0.4 7.2e-16 57.6 0.4 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain OCRE PF17780.1 CAR25635.1 - 0.4 10.7 2.7 0.33 11.0 0.3 2.1 2 0 0 2 2 2 0 OCRE domain Ran_BP1 PF00638.18 CAR25636.1 - 4.9e-54 181.8 1.1 6.9e-54 181.3 1.1 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CAR25636.1 - 0.0003 20.7 0.6 0.0037 17.2 0.6 2.1 1 1 0 1 1 1 1 WH1 domain DUF1041 PF06292.17 CAR25636.1 - 0.089 13.2 0.2 0.2 12.1 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) Prenyltransf PF01255.19 CAR25637.1 - 5e-72 242.0 0.0 6.1e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase polyprenyl_synt PF00348.17 CAR25638.1 - 4.3e-67 225.9 0.0 1.1e-65 221.3 0.0 2.4 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 CAR25638.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Mannosyl_trans2 PF04188.13 CAR25639.1 - 3.4e-97 326.6 39.2 1.2e-94 318.2 39.2 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) Mpv17_PMP22 PF04117.12 CAR25639.1 - 1.6 9.0 9.3 1.3 9.3 0.1 3.6 3 0 0 3 3 3 0 Mpv17 / PMP22 family RCR PF12273.8 CAR25640.1 - 1.4e-28 99.9 0.2 1.9e-28 99.5 0.2 1.3 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4064 PF13273.6 CAR25640.1 - 0.016 15.4 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF4834 PF16118.5 CAR25640.1 - 0.17 12.9 0.3 1.7 9.7 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) SLC3A2_N PF16028.5 CAR25640.1 - 1.4 8.5 3.4 2.5 7.7 3.4 1.3 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus PBP_N PF17093.5 CAR25640.1 - 1.9 8.7 6.2 2.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Aldedh PF00171.22 CAR25641.1 - 3.9e-159 530.1 0.3 4.4e-159 529.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CAR25641.1 - 5.3e-06 26.0 0.0 9.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) PTE PF02126.18 CAR25641.1 - 0.033 13.6 0.2 0.45 9.9 0.0 2.2 1 1 0 2 2 2 0 Phosphotriesterase family Rad51 PF08423.11 CAR25642.1 - 1.8e-43 148.7 0.0 3.8e-40 137.8 0.0 2.5 2 1 0 2 2 2 2 Rad51 AAA_25 PF13481.6 CAR25642.1 - 1.5e-08 34.4 0.1 4.5e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 CAR25642.1 - 0.00029 20.4 0.8 0.001 18.6 0.8 1.8 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CAR25642.1 - 0.0032 16.9 0.5 0.013 14.9 0.2 2.1 2 0 0 2 2 2 1 KaiC DUF1488 PF07369.11 CAR25642.1 - 0.15 12.1 0.0 0.83 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) AAA_24 PF13479.6 CAR25642.1 - 0.16 11.7 0.0 0.45 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Maf1 PF09174.10 CAR25643.1 - 2.4e-40 138.5 1.1 4.3e-40 137.7 1.1 1.4 1 1 0 1 1 1 1 Maf1 regulator M_domain PF12938.7 CAR25643.1 - 6.4 6.5 5.9 8.4 6.1 5.9 1.1 1 0 0 1 1 1 0 M domain of GW182 Sel1 PF08238.12 CAR25644.1 - 4.7e-07 30.3 2.8 0.092 13.5 0.1 3.4 3 0 0 3 3 3 2 Sel1 repeat Phage_Gp23 PF10669.9 CAR25644.1 - 7.1 7.0 17.8 61 4.0 17.8 2.5 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Tcp11 PF05794.13 CAR25645.1 - 1.2e-139 466.2 3.7 2e-139 465.5 3.7 1.4 1 0 0 1 1 1 1 T-complex protein 11 CENP-T_C PF15511.6 CAR25646.1 - 1.8e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CAR25646.1 - 1.4e-05 25.4 0.2 1.7e-05 25.2 0.2 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR25646.1 - 1.9e-05 24.9 0.1 3.2e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 CAR25646.1 - 2.5e-05 24.4 0.1 3.4e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 CAR25646.1 - 0.00016 22.0 0.1 0.00022 21.6 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CAR25646.1 - 0.0028 17.7 0.0 0.0034 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CAR25646.1 - 0.0093 16.0 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CAR25646.1 - 0.049 14.1 0.0 0.081 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 CAR25647.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CAR25647.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CAR25647.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CAR25647.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CAR25647.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CAR25647.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PRAI PF00697.22 CAR25648.1 - 1e-62 211.4 0.1 1.2e-62 211.2 0.1 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Pyrophosphatase PF00719.19 CAR25649.1 - 8.2e-58 194.7 0.2 1.1e-57 194.3 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase zf-ANAPC11 PF12861.7 CAR25650.1 - 7.5e-45 150.9 6.0 1e-44 150.5 6.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CAR25650.1 - 7.3e-22 77.4 10.1 1.2e-21 76.8 10.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CAR25650.1 - 1.8e-07 31.4 15.3 2.1e-06 28.0 15.3 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAR25650.1 - 6.6e-05 22.7 3.3 6.6e-05 22.7 3.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR25650.1 - 0.00085 19.3 6.2 0.0079 16.2 3.3 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 CAR25650.1 - 0.011 15.5 12.9 0.61 9.9 9.2 3.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 CAR25650.1 - 0.012 15.5 14.1 0.059 13.2 14.1 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR25650.1 - 0.014 15.4 13.3 0.11 12.4 13.7 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CAR25650.1 - 0.023 14.6 12.3 0.97 9.3 12.3 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CAR25650.1 - 0.03 14.5 2.8 0.03 14.5 2.8 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HIT PF04438.16 CAR25650.1 - 0.051 13.4 4.6 0.051 13.4 4.6 2.0 2 0 0 2 2 2 0 HIT zinc finger FANCL_C PF11793.8 CAR25650.1 - 0.063 13.5 12.5 0.34 11.1 12.5 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CAR25650.1 - 0.14 11.8 9.5 0.28 10.8 9.5 1.6 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CAR25650.1 - 0.21 11.3 10.4 1.4 8.7 10.4 2.3 1 1 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 CAR25650.1 - 0.28 11.2 10.4 0.43 10.6 5.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-HC5HC2H_2 PF13832.6 CAR25650.1 - 0.38 10.9 7.8 0.15 12.2 4.8 1.8 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CAR25650.1 - 0.75 10.1 7.8 2.1 8.7 7.9 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain RINGv PF12906.7 CAR25650.1 - 1.7 8.8 10.6 7.1 6.8 10.6 2.0 1 1 0 1 1 1 0 RING-variant domain Glutaredoxin PF00462.24 CAR25651.1 - 9e-15 54.6 0.0 1.4e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 CAR25651.1 - 0.045 14.2 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like domain Mannosyl_trans3 PF11051.8 CAR25652.1 - 5.5e-83 278.5 0.0 7.6e-83 278.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative CYSTM PF12734.7 CAR25653.1 - 2e-13 50.4 8.4 2e-13 50.4 8.4 4.1 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 CAR25653.1 - 9.6 6.8 7.2 16 6.2 7.2 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C3HC4_2 PF13923.6 CAR25654.1 - 0.0031 17.3 0.1 0.0081 16.0 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR25654.1 - 0.0057 16.6 0.8 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CAR25654.1 - 0.0071 16.3 0.6 0.017 15.1 0.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CAR25654.1 - 0.0079 16.0 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Tubulin PF00091.25 CAR25654.1 - 0.024 14.8 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain zf-C3HC4_3 PF13920.6 CAR25654.1 - 0.027 14.3 0.1 0.027 14.3 0.1 1.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR25654.1 - 0.032 14.1 0.0 0.084 12.8 0.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR25654.1 - 0.071 13.5 0.1 0.23 11.8 0.1 1.8 1 0 0 1 1 1 0 Ring finger domain DUF2514 PF10721.9 CAR25654.1 - 0.31 11.1 0.1 0.31 11.1 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2514) Fibrillarin PF01269.17 CAR25655.1 - 1.6e-106 354.5 0.0 1.9e-106 354.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CAR25655.1 - 9.5e-06 25.5 0.0 1.5e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 CAR25655.1 - 0.0028 17.8 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 CAR25655.1 - 0.067 12.8 0.0 0.2 11.3 0.0 1.8 3 0 0 3 3 3 0 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 CAR25655.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Steroid_dh PF02544.16 CAR25656.1 - 6.6e-31 107.3 11.3 1.1e-30 106.6 11.3 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase GlcV_C_terminal PF17847.1 CAR25656.1 - 0.11 12.9 0.0 5.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Glucose ABC transporter C-terminal domain PB1 PF00564.24 CAR25656.1 - 0.16 12.0 0.1 0.83 9.6 0.1 2.0 2 0 0 2 2 2 0 PB1 domain Pkinase PF00069.25 CAR25657.1 - 4.9e-39 134.3 0.0 5.7e-20 71.8 0.0 3.8 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25657.1 - 1.7e-14 53.8 0.0 8.3e-09 35.1 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CAR25657.1 - 0.0031 17.5 0.0 0.0074 16.2 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CAR25657.1 - 0.0038 16.6 0.0 3.2 7.0 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 CAR25657.1 - 0.015 14.1 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 CAR25657.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 EMP24_GP25L PF01105.24 CAR25658.1 - 1.3e-31 110.0 0.0 1.5e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Amidohydro_1 PF01979.20 CAR25659.1 - 1.9e-40 139.3 0.0 2.3e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CAR25659.1 - 4.5e-15 56.1 0.0 1.2e-09 38.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family HEAT PF02985.22 CAR25660.1 - 9.5e-20 69.0 5.8 0.0017 18.4 0.0 8.0 8 0 0 8 8 7 4 HEAT repeat HEAT_EZ PF13513.6 CAR25660.1 - 5.6e-18 65.1 2.3 1.3e-10 41.5 0.0 7.0 7 1 1 8 8 7 2 HEAT-like repeat HEAT_2 PF13646.6 CAR25660.1 - 9.5e-11 42.0 0.0 0.0016 18.8 0.0 5.7 6 1 1 7 7 7 2 HEAT repeats Cnd1 PF12717.7 CAR25660.1 - 8.9e-07 29.1 2.3 0.2 11.7 0.0 4.0 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CAR25660.1 - 2.3e-05 23.1 1.0 0.036 12.6 0.0 3.2 3 1 0 3 3 3 2 Adaptin N terminal region IBN_N PF03810.19 CAR25660.1 - 0.00021 21.1 3.0 0.0051 16.7 0.3 3.9 3 1 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 CAR25660.1 - 0.00096 19.7 0.0 5.3 7.7 0.0 4.1 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CAR25660.1 - 0.003 17.1 0.1 0.27 10.8 0.0 3.7 5 0 0 5 5 5 1 CLASP N terminal UNC45-central PF11701.8 CAR25660.1 - 0.0052 16.8 1.0 0.015 15.2 0.3 2.1 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central TIP120 PF08623.10 CAR25660.1 - 0.013 15.2 1.5 0.26 11.0 0.1 3.6 5 0 0 5 5 5 0 TATA-binding protein interacting (TIP20) Urb2 PF10441.9 CAR25660.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Urb2/Npa2 family DNA_pol_phi PF04931.13 CAR25660.1 - 2.3 6.2 10.3 6 4.8 10.3 1.6 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 CAR25660.1 - 7.2 5.0 6.7 6.4 5.2 3.4 2.5 4 0 0 4 4 4 0 RNA polymerase I specific transcription initiation factor RRN3 SH3_1 PF00018.28 CAR25661.1 - 7.7e-10 38.2 0.0 2e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR25661.1 - 0.04 13.8 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain SAICAR_synt PF01259.18 CAR25662.1 - 8e-101 336.9 0.0 9.4e-101 336.6 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase UPF0086 PF01868.16 CAR25662.1 - 0.028 14.3 0.1 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function UPF0086 HELP PF03451.14 CAR25662.1 - 0.12 12.2 0.1 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 HELP motif Pkinase PF00069.25 CAR25663.1 - 1.1e-54 185.6 0.3 8.4e-54 182.7 0.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25663.1 - 9.2e-33 113.6 0.0 2.5e-32 112.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR25663.1 - 0.0033 16.2 0.0 0.0055 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase PPP5 PF08321.12 CAR25663.1 - 0.083 13.2 0.8 0.22 11.8 0.1 2.0 2 0 0 2 2 2 0 PPP5 TPR repeat region APH PF01636.23 CAR25663.1 - 0.1 12.5 0.0 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 CAR25664.1 - 1.4e-76 257.4 0.3 2.7e-76 256.4 0.3 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25664.1 - 2.8e-56 190.7 0.1 6.8e-56 189.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR25664.1 - 2.8e-05 23.6 0.2 0.00014 21.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CAR25664.1 - 0.028 13.2 0.0 0.062 12.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CAR25664.1 - 0.072 12.4 0.1 0.16 11.3 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Carn_acyltransf PF00755.20 CAR25665.1 - 3.8e-206 686.3 0.0 4.3e-206 686.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Oxysterol_BP PF01237.18 CAR25666.1 - 1.4e-132 442.1 0.1 1.4e-132 442.1 0.1 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein PH PF00169.29 CAR25666.1 - 2.8e-12 47.0 0.1 6.8e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 PH domain Ank_5 PF13857.6 CAR25666.1 - 1.1e-10 41.5 0.1 6.9e-06 26.2 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CAR25666.1 - 2.8e-09 37.3 0.0 0.0058 17.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR25666.1 - 4.2e-08 33.7 0.0 0.0041 17.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) PH_8 PF15409.6 CAR25666.1 - 1.3e-07 31.7 0.2 3.3e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_3 PF13606.6 CAR25666.1 - 8e-07 28.9 0.0 0.051 14.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CAR25666.1 - 3.4e-05 24.1 0.0 0.18 12.3 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat PH_11 PF15413.6 CAR25666.1 - 0.0095 16.3 4.9 0.022 15.2 1.0 3.5 3 1 0 3 3 3 1 Pleckstrin homology domain Phos_pyr_kin PF08543.12 CAR25667.1 - 4.4e-77 258.8 0.1 5.5e-77 258.5 0.1 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CAR25667.1 - 1.6e-58 198.0 0.1 2.2e-58 197.5 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.15 CAR25667.1 - 1.2e-05 24.8 0.1 2.9e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family PfkB PF00294.24 CAR25667.1 - 0.033 13.5 0.0 0.09 12.1 0.0 1.7 1 1 0 1 1 1 0 pfkB family carbohydrate kinase zf-C2H2 PF00096.26 CAR25668.1 - 0.00076 19.8 10.4 0.066 13.7 0.4 3.1 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR25668.1 - 0.027 15.3 6.5 2.5 9.2 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR25668.1 - 0.041 14.3 2.5 1 9.9 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CAR25668.1 - 0.042 14.1 1.5 11 6.5 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CAR25668.1 - 0.24 11.4 7.0 2.6 8.1 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2457 PF10446.9 CAR25668.1 - 10 5.2 21.6 0.37 9.9 15.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) His_Phos_1 PF00300.22 CAR25669.1 - 4.9e-31 107.9 0.1 1.3e-14 54.4 0.0 3.0 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) Phage_TAC_3 PF06896.11 CAR25669.1 - 0.043 14.4 0.0 0.089 13.4 0.0 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone proteins, TAC Peptidase_M49 PF03571.15 CAR25670.1 - 1.8e-232 772.6 0.0 2.6e-232 772.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M49 Arginosuc_synth PF00764.19 CAR25671.1 - 8.6e-163 542.1 0.0 1e-162 541.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CAR25671.1 - 0.00044 19.8 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CAR25671.1 - 0.0024 16.7 0.0 0.0036 16.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 CAR25671.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase DUF2790 PF10976.8 CAR25671.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) NAD_Gly3P_dh_N PF01210.23 CAR25672.1 - 1.3e-51 174.6 0.0 2.4e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CAR25672.1 - 6.6e-41 139.9 0.1 1.1e-40 139.2 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CAR25672.1 - 0.028 15.0 0.0 12 6.5 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CAR25672.1 - 0.066 13.1 0.3 2 8.3 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_Me_trans PF04252.13 CAR25673.1 - 7.7e-79 263.9 0.0 8.6e-79 263.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Cpn10 PF00166.21 CAR25674.1 - 1.5e-26 92.3 0.0 1.7e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PRP3 PF08572.10 CAR25675.1 - 6.8e-55 186.2 17.6 1.2e-54 185.5 17.6 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CAR25675.1 - 3.5e-32 111.5 0.5 3.5e-32 111.5 0.5 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1115) YliH PF10799.8 CAR25675.1 - 0.14 12.1 0.3 1.3 8.9 0.1 2.4 1 1 0 2 2 2 0 Biofilm formation protein (YliH/bssR) Arf PF00025.21 CAR25677.1 - 2.5e-31 108.5 0.0 3.3e-30 104.8 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.22 CAR25677.1 - 2.9e-12 46.5 0.0 3.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CAR25677.1 - 6.5e-11 42.0 0.5 8.6e-09 35.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CAR25677.1 - 6.7e-11 42.5 0.0 1e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CAR25677.1 - 1.8e-09 37.7 0.0 2.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CAR25677.1 - 2.6e-06 27.0 0.0 3.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CAR25677.1 - 4.5e-06 26.2 0.1 6.2e-06 25.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CAR25677.1 - 4.9e-05 23.0 0.0 0.0022 17.5 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CAR25677.1 - 0.00051 19.6 0.6 0.0012 18.4 0.6 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CAR25677.1 - 0.0028 17.5 0.3 1.3 8.7 0.1 2.1 1 1 0 2 2 2 2 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 CAR25677.1 - 0.01 15.9 0.1 0.027 14.5 0.0 1.7 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 CAR25677.1 - 0.11 12.2 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CAR25677.1 - 0.13 11.9 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 CAR25677.1 - 0.14 12.7 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2470 PF10615.9 CAR25678.1 - 8e-11 42.4 0.0 1.2e-10 41.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Kelch_5 PF13854.6 CAR25678.1 - 0.087 12.8 0.5 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 Kelch motif Pkinase PF00069.25 CAR25679.1 - 7.6e-75 251.7 0.0 1.3e-74 250.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain AdenylateSensor PF16579.5 CAR25679.1 - 3.5e-57 191.9 0.8 7.2e-57 190.9 0.1 2.0 2 0 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Pkinase_Tyr PF07714.17 CAR25679.1 - 1.1e-36 126.4 0.0 1.7e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.11 CAR25679.1 - 1.9e-20 72.7 3.9 2.4e-20 72.4 1.7 2.2 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 CAR25679.1 - 6.8e-10 38.7 0.0 1.6e-09 37.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 CAR25679.1 - 9.7e-05 22.0 0.7 0.0002 21.0 0.7 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.9 CAR25679.1 - 0.00018 20.5 0.6 0.00034 19.6 0.6 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 CAR25679.1 - 0.0003 19.9 0.5 0.00052 19.1 0.5 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CAR25679.1 - 0.0052 16.2 0.2 0.0052 16.2 0.2 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR25679.1 - 0.012 15.5 0.2 0.68 9.8 0.2 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family GEP5 PF17053.5 CAR25679.1 - 0.014 15.3 0.4 0.095 12.5 0.4 2.2 2 0 0 2 2 2 0 Genetic interactor of prohibitin 5 YqzL PF14006.6 CAR25679.1 - 0.16 12.4 6.0 2 8.8 2.1 2.7 2 0 0 2 2 2 0 YqzL-like protein SIR2 PF02146.17 CAR25680.1 - 2.2e-37 128.7 0.0 2.4e-22 79.7 0.0 2.4 2 0 0 2 2 2 2 Sir2 family CRA PF06589.11 CAR25680.1 - 0.22 11.6 0.0 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Zn-ribbon_8 PF09723.10 CAR25680.1 - 0.52 10.5 4.1 1.2 9.4 4.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Rpr2 PF04032.16 CAR25681.1 - 4e-13 49.5 0.0 4e-13 49.5 0.0 2.1 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.7 CAR25681.1 - 0.0074 16.3 1.4 0.017 15.1 1.4 1.6 1 1 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 CAR25681.1 - 0.031 14.0 0.1 0.031 14.0 0.1 1.9 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 CAR25681.1 - 0.043 13.2 1.4 0.087 12.3 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 CAR25681.1 - 0.42 10.4 0.2 0.42 10.4 0.2 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Pex24p PF06398.11 CAR25682.1 - 1.3e-72 244.9 7.0 1.6e-72 244.5 7.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin WD40_like PF17005.5 CAR25683.1 - 1.1e-05 24.9 0.2 0.0018 17.6 0.0 2.5 3 0 0 3 3 3 2 WD40-like domain WD40 PF00400.32 CAR25683.1 - 0.00012 22.8 10.0 0.006 17.4 0.1 5.4 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR25683.1 - 0.0035 17.6 0.2 6.8 7.1 0.0 4.2 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PHTB1_N PF14727.6 CAR25683.1 - 0.017 14.5 0.2 1 8.7 0.0 2.6 3 0 0 3 3 3 0 PTHB1 N-terminus PQQ_3 PF13570.6 CAR25683.1 - 0.3 11.6 3.6 66 4.2 0.0 5.0 7 0 0 7 7 7 0 PQQ-like domain SET PF00856.28 CAR25684.1 - 1.9e-16 60.9 0.0 3e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 SET domain TPR_1 PF00515.28 CAR25685.1 - 4.3e-47 156.1 17.8 4.7e-07 29.3 0.1 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 CAR25685.1 - 2.4e-36 120.9 20.9 8e-05 22.5 0.2 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 CAR25685.1 - 1.4e-33 114.6 12.8 1.8e-16 59.8 2.4 2.7 2 0 0 2 2 2 2 STI1 domain TPR_11 PF13414.6 CAR25685.1 - 8.1e-24 83.0 15.3 0.0061 16.2 0.0 8.4 7 1 1 8 8 8 6 TPR repeat TPR_12 PF13424.6 CAR25685.1 - 3.2e-23 81.8 10.3 3.9e-09 36.7 0.8 6.0 5 2 1 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 CAR25685.1 - 1.9e-20 71.3 19.1 0.0073 16.4 0.3 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 CAR25685.1 - 2.3e-16 60.2 10.3 0.0006 20.4 0.0 6.9 3 3 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CAR25685.1 - 1.5e-15 56.5 9.4 1.6 9.8 0.1 9.1 4 3 5 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 CAR25685.1 - 1e-14 54.7 13.5 0.001 19.5 0.1 7.1 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 CAR25685.1 - 1.5e-10 40.3 7.0 0.29 11.2 0.1 6.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR25685.1 - 8.3e-10 38.4 5.6 1.7 9.2 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAR25685.1 - 5.3e-07 29.7 0.1 0.0055 16.8 0.0 4.2 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAR25685.1 - 8.5e-06 26.1 18.8 0.49 11.2 0.1 8.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAR25685.1 - 1.3e-05 24.9 10.7 1.9 8.5 0.0 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat DUF3808 PF10300.9 CAR25685.1 - 0.00021 20.2 5.9 0.0031 16.3 0.2 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 CAR25685.1 - 0.00051 20.2 12.3 0.39 11.0 0.4 5.0 3 3 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 CAR25685.1 - 0.00083 18.8 7.3 0.48 9.9 0.1 5.7 7 0 0 7 7 7 1 SHNi-TPR PPR PF01535.20 CAR25685.1 - 0.013 15.7 0.8 78 3.8 0.1 5.5 6 0 0 6 6 6 0 PPR repeat DUF627 PF04781.12 CAR25685.1 - 0.023 14.7 2.6 29 4.7 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF627) ChAPs PF09295.10 CAR25685.1 - 0.06 12.3 1.7 1.3 7.9 0.1 2.3 2 1 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) Erf4 PF10256.9 CAR25685.1 - 0.074 13.2 1.3 13 5.9 0.1 3.5 2 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family DUF498 PF04430.14 CAR25685.1 - 0.093 12.8 1.2 5.3 7.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) PPR_2 PF13041.6 CAR25685.1 - 0.56 10.5 4.6 17 5.7 0.0 4.7 5 1 1 6 6 6 0 PPR repeat family TPR_20 PF14561.6 CAR25685.1 - 1.6 9.1 11.7 6.5 7.2 0.2 5.4 4 3 3 7 7 6 0 Tetratricopeptide repeat Trypan_PARP PF05887.11 CAR25685.1 - 1.7 8.6 14.9 0.81 9.7 11.9 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) adh_short PF00106.25 CAR25686.1 - 8.3e-53 178.8 0.1 1e-52 178.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR25686.1 - 2.9e-34 118.7 0.1 3.6e-34 118.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR25686.1 - 2e-12 47.4 0.0 2.7e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CAR25686.1 - 0.00014 21.1 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.10 CAR25686.1 - 0.00094 18.6 0.0 0.0022 17.4 0.0 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 CAR25686.1 - 0.001 18.6 0.2 0.0079 15.7 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CAR25686.1 - 0.043 14.1 0.2 0.14 12.4 0.0 1.9 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain AMMECR1 PF01871.17 CAR25687.1 - 2e-37 128.3 0.0 2.3e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 APP_N PF02177.16 CAR25687.1 - 0.013 15.9 0.3 0.033 14.6 0.1 1.7 1 1 1 2 2 2 0 Amyloid A4 N-terminal heparin-binding Thioredoxin PF00085.20 CAR25688.1 - 1.8e-23 82.5 0.8 5.7e-23 80.9 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CAR25688.1 - 1.4e-06 28.7 0.9 6e-06 26.7 0.2 2.3 3 0 0 3 3 3 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CAR25688.1 - 3.6e-05 23.3 0.1 5.7e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 CAR25688.1 - 0.00021 21.3 1.1 0.8 9.6 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CAR25688.1 - 0.00086 19.6 0.4 0.42 11.0 0.1 3.2 2 1 1 3 3 3 2 Thioredoxin-like TraF PF13728.6 CAR25688.1 - 0.0015 18.4 0.2 0.0038 17.1 0.1 1.6 2 0 0 2 2 2 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 CAR25688.1 - 0.061 13.4 0.3 0.14 12.2 0.3 1.5 1 0 0 1 1 1 0 Thioredoxin domain DSBA PF01323.20 CAR25688.1 - 0.078 12.7 0.2 0.15 11.8 0.2 1.6 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.6 CAR25688.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 CAR25688.1 - 0.11 12.6 0.2 0.41 10.8 0.1 2.0 2 0 0 2 2 2 0 Thioredoxin-like MRP_L53 PF10780.9 CAR25689.1 - 3.8e-21 75.0 0.4 5.5e-21 74.5 0.4 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 RRP36 PF06102.12 CAR25690.1 - 9.1e-41 139.6 24.9 9.1e-41 139.6 24.9 2.7 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 Rhodanese PF00581.20 CAR25691.1 - 3.9e-14 53.1 0.0 5.1e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 CAR25692.1 - 5.9e-15 55.7 0.0 7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain His_Phos_1 PF00300.22 CAR25693.1 - 1.3e-39 135.9 0.0 1.6e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CRAL_TRIO_2 PF13716.6 CAR25693.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Mre11_DNA_bind PF04152.14 CAR25694.1 - 4.1e-48 163.9 1.2 5.9e-48 163.4 0.1 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CAR25694.1 - 8.2e-12 46.0 0.7 1.7e-11 45.0 0.7 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Phosducin PF02114.16 CAR25695.1 - 1.9e-12 46.7 6.3 8.1e-12 44.6 6.3 1.8 1 1 0 1 1 1 1 Phosducin YicC_N PF03755.13 CAR25695.1 - 0.18 12.3 1.5 0.31 11.5 0.1 2.1 3 0 0 3 3 3 0 YicC-like family, N-terminal region UCH PF00443.29 CAR25696.1 - 5.9e-50 170.2 3.2 8.8e-50 169.6 3.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR25696.1 - 4e-18 66.1 13.6 6.8e-18 65.3 7.9 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CAR25696.1 - 5.1e-11 42.7 8.3 5.1e-11 42.7 8.3 3.1 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein DUF5124 PF17160.4 CAR25696.1 - 0.79 10.5 3.0 1.9 9.3 0.3 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5124) FSH1 PF03959.13 CAR25697.1 - 1.5e-61 207.7 0.0 1.7e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CAR25697.1 - 0.00031 20.6 0.3 0.0016 18.3 0.1 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.10 CAR25697.1 - 0.042 14.0 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 CAR25698.1 - 7.1e-65 218.6 0.0 8.6e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CAR25698.1 - 0.00054 19.8 0.1 0.0015 18.4 0.1 1.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase CLCA PF08434.11 CAR25698.1 - 0.0071 15.7 0.1 0.0099 15.2 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel N terminal Peptidase_S15 PF02129.18 CAR25698.1 - 0.008 15.8 0.3 0.031 13.9 0.0 2.0 2 1 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CAR25698.1 - 0.029 13.6 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAR25698.1 - 0.068 12.8 1.4 4.4 6.9 0.0 2.7 1 1 0 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.16 CAR25699.1 - 2.2e-15 56.5 11.0 2.5e-15 56.3 8.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GHMP_kinases_N PF00288.26 CAR25701.1 - 1.7e-14 53.8 0.3 3.6e-14 52.7 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CAR25701.1 - 8.5e-07 29.2 0.0 2.2e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 GHMP kinases C terminal Rad33 PF08730.10 CAR25701.1 - 0.039 14.0 0.4 0.66 9.9 0.0 2.2 2 0 0 2 2 2 0 Rad33 EzrA PF06160.12 CAR25701.1 - 0.05 11.8 0.7 0.086 11.0 0.7 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.12 CAR25701.1 - 0.53 10.8 2.5 1.8 9.1 2.5 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Trypan_PARP PF05887.11 CAR25702.1 - 0.0001 22.3 92.4 0.0008 19.4 47.6 9.0 6 3 3 9 9 9 2 Procyclic acidic repetitive protein (PARP) TRAPPC10 PF12584.8 CAR25703.1 - 8.5e-08 32.1 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 CAR25703.1 - 0.011 15.3 0.0 0.029 13.9 0.0 1.6 2 0 0 2 2 2 0 Foie gras liver health family 1 TPR_12 PF13424.6 CAR25703.1 - 0.041 14.2 0.3 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAR25703.1 - 0.072 13.2 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAR25703.1 - 0.19 11.7 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat HEM4 PF02602.15 CAR25704.1 - 1e-43 149.4 0.0 1.2e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD GMP_synt_C PF00958.22 CAR25705.1 - 7.6e-45 150.9 0.0 1.4e-44 150.1 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CAR25705.1 - 5.3e-41 140.5 0.0 7.9e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CAR25705.1 - 9.8e-08 31.4 0.1 0.00052 19.2 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CAR25705.1 - 7.3e-07 29.2 0.1 4.7e-06 26.5 0.1 2.2 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 CAR25705.1 - 0.062 12.1 0.1 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 tRNA methyl transferase Arginosuc_synth PF00764.19 CAR25705.1 - 0.063 12.6 0.1 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.19 CAR25705.1 - 0.12 12.4 0.1 0.28 11.2 0.0 1.6 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family Pkinase PF00069.25 CAR25706.1 - 1.1e-41 143.0 0.6 6.8e-20 71.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25706.1 - 1.1e-10 41.2 2.2 7.4e-08 32.0 0.7 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_72 PF03198.14 CAR25707.1 - 3.5e-123 410.9 4.8 6.1e-123 410.1 4.8 1.3 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 CAR25707.1 - 5.3e-09 35.6 0.1 1.1e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 CAR25707.1 - 1.2e-06 28.1 0.3 0.016 14.7 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) HGTP_anticodon PF03129.20 CAR25707.1 - 0.08 13.1 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Anticodon binding domain DnaJ PF00226.31 CAR25708.1 - 1.4e-26 92.4 0.4 2.3e-26 91.7 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CAR25708.1 - 1.2e-23 83.9 0.0 1.4e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CAR25708.1 - 2.7e-14 53.2 16.2 4.4e-14 52.6 16.2 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CAR25708.1 - 2.1e-06 27.6 9.8 0.00088 19.2 1.9 2.3 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein FdhE PF04216.12 CAR25708.1 - 0.12 12.3 3.2 0.18 11.6 3.2 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation HypA PF01155.19 CAR25708.1 - 0.14 12.2 8.7 1.7 8.7 0.9 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-IS66 PF13005.7 CAR25708.1 - 6.7 7.2 8.4 22 5.6 0.1 3.3 3 0 0 3 3 3 0 zinc-finger binding domain of transposase IS66 CAF20 PF17052.5 CAR25709.1 - 1e-53 181.7 2.5 1.2e-53 181.5 2.5 1.0 1 0 0 1 1 1 1 Cap associated factor Septin PF00735.18 CAR25710.1 - 3.7e-112 374.2 0.0 5.5e-112 373.6 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CAR25710.1 - 3.5e-06 27.1 0.0 7.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR25710.1 - 0.00036 20.1 0.5 0.017 14.7 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CAR25710.1 - 0.00054 20.2 0.0 0.0015 18.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CAR25710.1 - 0.0011 18.8 0.7 0.0011 18.8 0.7 3.1 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 CAR25710.1 - 0.0025 18.2 0.1 0.0098 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain IIGP PF05049.13 CAR25710.1 - 0.0045 16.1 0.0 0.0086 15.2 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 CAR25710.1 - 0.011 15.5 0.3 0.029 14.1 0.3 1.8 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CAR25710.1 - 0.012 15.7 4.6 0.81 9.7 0.0 3.1 2 1 0 3 3 3 0 Dynamin family AIG1 PF04548.16 CAR25710.1 - 0.015 14.6 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 AIG1 family RNA_helicase PF00910.22 CAR25710.1 - 0.021 15.2 0.0 0.052 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 CAR25710.1 - 0.042 14.3 0.2 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Roc PF08477.13 CAR25710.1 - 0.061 13.5 0.4 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 CAR25710.1 - 0.063 13.2 0.5 0.12 12.3 0.2 1.6 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.18 CAR25710.1 - 0.08 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 CAR25710.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CAR25710.1 - 0.089 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 CAR25710.1 - 0.2 11.8 0.9 0.48 10.6 0.2 2.0 2 0 0 2 2 2 0 AAA domain PGBA_C PF15437.6 CAR25710.1 - 1 9.8 6.4 2 8.8 6.4 1.5 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Pyr_redox_2 PF07992.14 CAR25711.1 - 5.5e-49 167.0 0.4 6.5e-49 166.7 0.4 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR25711.1 - 1.7e-20 73.3 0.3 4.5e-17 62.4 0.1 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR25711.1 - 1.4e-15 57.4 0.3 5.2e-14 52.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CAR25711.1 - 6.5e-06 25.5 1.5 0.47 9.5 0.2 3.7 3 1 0 4 4 4 3 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CAR25711.1 - 0.00021 20.5 1.4 0.07 12.2 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 CAR25711.1 - 0.00038 19.8 0.1 0.0021 17.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 CAR25711.1 - 0.00066 19.8 0.1 0.025 14.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 CAR25711.1 - 0.00075 19.9 0.0 0.21 12.0 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 CAR25711.1 - 0.005 16.0 0.4 9.6 5.2 0.1 3.3 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 CAR25711.1 - 0.0073 15.7 0.2 0.27 10.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CAR25711.1 - 0.086 12.1 0.2 2.9 7.0 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.16 CAR25711.1 - 0.16 11.6 1.6 0.51 10.0 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PX PF00787.24 CAR25712.1 - 1.1e-13 51.2 0.0 1.3e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 PX domain Glycolytic PF00274.19 CAR25712.1 - 0.2 10.4 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Aldo_ket_red PF00248.21 CAR25713.1 - 5.8e-45 153.7 0.0 8.9e-45 153.1 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family PQ-loop PF04193.14 CAR25714.1 - 3.4e-35 119.6 6.1 7.1e-18 64.1 0.7 2.6 2 0 0 2 2 2 2 PQ loop repeat FA_hydroxylase PF04116.13 CAR25714.1 - 0.025 14.9 4.7 0.33 11.3 0.8 2.4 2 0 0 2 2 2 0 Fatty acid hydroxylase superfamily MtN3_slv PF03083.16 CAR25714.1 - 0.037 14.1 3.0 1.2 9.2 0.0 2.9 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange SID-1_RNA_chan PF13965.6 CAR25714.1 - 0.13 10.7 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SBE2 PF17076.5 CAR25715.1 - 2.1e-285 949.1 35.9 1.7e-283 942.9 35.9 2.0 1 1 0 1 1 1 1 SBE2, cell-wall formation SIX1_SD PF16878.5 CAR25715.1 - 0.024 15.1 1.2 2 8.9 0.0 3.6 3 0 0 3 3 3 0 Transcriptional regulator, SIX1, N-terminal SD domain Androgen_recep PF02166.16 CAR25715.1 - 1.1 8.0 8.5 1.9 7.3 8.5 1.3 1 0 0 1 1 1 0 Androgen receptor Pkinase PF00069.25 CAR25716.1 - 3.5e-71 239.7 0.0 5.8e-71 238.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25716.1 - 1.7e-52 178.3 0.0 2.5e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR25716.1 - 1.3e-06 27.4 0.1 5.5e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CAR25716.1 - 6.1e-05 22.5 0.2 0.0045 16.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 CAR25716.1 - 0.073 12.0 0.1 0.3 10.0 0.1 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Sec7_N PF12783.7 CAR25718.1 - 0.095 12.6 0.2 0.76 9.7 0.2 2.2 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal PGP_phosphatase PF09419.10 CAR25719.1 - 5.2e-69 231.2 0.0 5.9e-69 231.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 CAR25719.1 - 8.7e-06 25.7 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like FAT PF02259.23 CAR25720.1 - 8.5e-72 242.2 8.7 2e-71 241.0 8.7 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CAR25720.1 - 8e-54 183.1 0.6 2.7e-53 181.4 0.6 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CAR25720.1 - 0.0033 17.2 0.1 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 FATC domain Sec7_N PF12783.7 CAR25720.1 - 0.06 13.3 4.8 0.18 11.7 0.0 4.5 4 0 0 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal NusA_N PF08529.11 CAR25720.1 - 0.067 13.6 0.5 17 5.8 0.1 3.3 3 0 0 3 3 3 0 NusA N-terminal domain Condensin2nSMC PF12422.8 CAR25720.1 - 0.18 12.0 7.0 4.2 7.5 0.2 4.6 3 1 1 4 4 4 0 Condensin II non structural maintenance of chromosomes subunit PXA PF02194.15 CAR25720.1 - 1.5 8.7 4.8 11 6.0 0.1 4.2 3 0 0 3 3 3 0 PXA domain Asp PF00026.23 CAR25721.1 - 4.5e-30 105.2 4.0 4.5e-30 105.2 4.0 2.5 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR25721.1 - 0.00094 19.5 0.7 0.00094 19.5 0.7 3.1 3 2 0 3 3 3 1 Xylanase inhibitor N-terminal Trypan_PARP PF05887.11 CAR25721.1 - 0.028 14.4 1.1 0.092 12.7 0.3 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Sec23_trunk PF04811.15 CAR25722.1 - 2e-55 188.0 0.0 4.2e-55 187.0 0.0 1.5 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CAR25722.1 - 1.2e-17 63.5 0.1 2.5e-17 62.6 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CAR25722.1 - 3.6e-12 46.8 0.0 7.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CAR25722.1 - 7.8e-11 41.8 0.5 1.7e-10 40.8 0.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CAR25722.1 - 6.7e-08 32.3 0.0 1.5e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Pal1 PF08316.11 CAR25723.1 - 3e-49 167.3 2.6 3e-49 167.3 2.6 2.9 2 1 1 3 3 3 1 Pal1 cell morphology protein RR_TM4-6 PF06459.12 CAR25723.1 - 2.2 8.0 4.3 0.77 9.5 1.5 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 FAM76 PF16046.5 CAR25723.1 - 7.3 5.9 6.8 13 5.1 6.8 1.3 1 0 0 1 1 1 0 FAM76 protein Sod_Fe_C PF02777.18 CAR25724.1 - 1.5e-11 44.4 0.2 0.00012 22.2 0.1 2.4 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DUF3847 PF12958.7 CAR25724.1 - 0.47 10.6 2.4 1 9.5 2.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) Svf1 PF08622.10 CAR25725.1 - 5.2e-70 234.7 0.7 1.1e-69 233.7 0.7 1.6 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 CAR25725.1 - 2.9e-63 212.6 2.3 6.2e-63 211.5 2.3 1.6 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain eIF_4G1 PF12152.8 CAR25725.1 - 0.063 13.5 0.1 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 PPL5 PF18168.1 CAR25725.1 - 0.24 10.7 2.2 0.48 9.7 2.2 1.4 1 0 0 1 1 1 0 Prim-pol family 5 DUF4820 PF16091.5 CAR25725.1 - 0.69 9.2 4.9 0.45 9.8 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Sugar_tr PF00083.24 CAR25726.1 - 4.2e-169 563.2 33.6 4.8e-169 563.0 33.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR25726.1 - 9.2e-27 93.9 31.3 2.2e-25 89.4 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_1d PF00750.19 CAR25727.1 - 3.9e-116 387.8 4.9 5e-116 387.5 4.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CAR25727.1 - 4.6e-28 97.8 0.2 9.2e-28 96.8 0.2 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CAR25727.1 - 2.9e-13 50.2 0.0 1.9e-11 44.4 0.0 2.8 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Fcf1 PF04900.12 CAR25728.1 - 1.8e-34 118.1 0.9 2.6e-34 117.6 0.4 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CAR25728.1 - 1e-14 54.8 0.0 1.5e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 CAR25728.1 - 0.026 14.8 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein ING PF12998.7 CAR25729.1 - 4.1e-23 81.9 5.8 6.3e-23 81.3 5.8 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CAR25729.1 - 9.7e-07 28.6 8.9 9.7e-07 28.6 8.9 1.7 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 CAR25729.1 - 0.0067 16.7 1.0 0.0067 16.7 1.0 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain Cas_Csn2 PF09711.10 CAR25729.1 - 0.052 13.2 0.8 0.081 12.6 0.8 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csn2) DUF4749 PF15936.5 CAR25729.1 - 1.5 10.0 7.0 0.18 12.9 2.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4749) Lge1 PF11488.8 CAR25729.1 - 6.5 7.0 7.6 7.4 6.8 2.3 2.4 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 MatE PF01554.18 CAR25730.1 - 3.7e-60 202.2 38.6 8.8e-40 136.0 7.7 3.2 3 0 0 3 3 3 2 MatE Abhydrolase_1 PF00561.20 CAR25731.1 - 4.7e-40 137.9 0.1 8.6e-40 137.0 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR25731.1 - 0.0014 18.0 0.0 0.0023 17.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 CAR25731.1 - 0.0018 18.0 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Tannase PF07519.11 CAR25731.1 - 0.006 15.5 0.0 0.0087 15.0 0.0 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Ribosomal_S15 PF00312.22 CAR25732.1 - 6.7e-29 99.9 1.0 1.3e-28 99.0 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 Gar1 PF04410.14 CAR25733.1 - 3.4e-39 134.1 0.0 4.1e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region MMR_HSR1 PF01926.23 CAR25734.1 - 2.9e-19 69.2 0.0 1e-17 64.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR25734.1 - 4.8e-07 29.8 0.1 3.6e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 CAR25734.1 - 9.3e-07 28.5 0.0 2.3e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CAR25734.1 - 7.2e-05 22.9 0.1 0.18 11.9 0.2 2.5 1 1 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 CAR25734.1 - 9.7e-05 22.0 0.0 0.00046 19.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CAR25734.1 - 0.00013 21.4 0.0 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit IIGP PF05049.13 CAR25734.1 - 0.00099 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Septin PF00735.18 CAR25734.1 - 0.0012 18.1 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Septin AIG1 PF04548.16 CAR25734.1 - 0.0034 16.7 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 CAR25734.1 - 0.0047 17.4 0.1 0.014 15.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 CAR25734.1 - 0.01 15.6 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CAR25734.1 - 0.066 13.6 0.0 0.18 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Xpo1 PF08389.12 CAR25735.1 - 0.0088 16.1 8.8 0.09 12.8 8.8 2.9 1 1 0 1 1 1 1 Exportin 1-like protein Brix PF04427.18 CAR25736.1 - 2.7e-26 92.9 1.1 4.4e-26 92.2 1.1 1.4 1 0 0 1 1 1 1 Brix domain DUF1764 PF08576.10 CAR25736.1 - 0.42 11.5 4.2 1 10.3 4.2 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) SBDS PF01172.18 CAR25738.1 - 8e-16 57.9 0.9 9e-16 57.7 0.9 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SNF2_N PF00176.23 CAR25739.1 - 1.6e-64 217.9 0.0 3.6e-64 216.7 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR25739.1 - 6.5e-18 65.1 0.0 5.4e-17 62.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.13 CAR25739.1 - 1.1e-17 64.0 6.8 5.3e-17 61.9 6.8 2.3 1 0 0 1 1 1 1 HSA ResIII PF04851.15 CAR25739.1 - 7.5e-12 45.6 0.1 3.4e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR25739.1 - 7.2e-06 25.9 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.22 CAR25740.1 - 1.7e-41 139.8 0.0 3.8e-17 61.9 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2722 PF10846.8 CAR25740.1 - 0.00016 20.8 20.7 0.00027 20.0 20.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RRM_occluded PF16842.5 CAR25740.1 - 0.00055 19.8 0.0 0.087 12.7 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CAR25740.1 - 0.0014 18.6 0.1 0.0078 16.2 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DDHD PF02862.17 CAR25740.1 - 0.0022 18.2 3.8 0.0036 17.5 3.8 1.4 1 0 0 1 1 1 1 DDHD domain MecA PF05389.12 CAR25740.1 - 0.003 17.2 2.0 0.0046 16.6 2.0 1.2 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) DUF775 PF05603.12 CAR25740.1 - 0.01 15.4 8.3 0.018 14.6 8.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF775) PAT1 PF09770.9 CAR25740.1 - 0.012 14.0 19.1 0.015 13.6 19.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 API5 PF05918.11 CAR25740.1 - 0.018 13.9 14.9 0.029 13.2 14.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Neur_chan_memb PF02932.16 CAR25740.1 - 0.02 15.0 1.9 0.03 14.4 1.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRM_7 PF16367.5 CAR25740.1 - 0.03 14.4 8.1 0.14 12.3 0.0 3.9 4 1 0 4 4 3 0 RNA recognition motif DUF1840 PF08895.11 CAR25740.1 - 0.063 13.6 11.7 0.12 12.8 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Gti1_Pac2 PF09729.9 CAR25740.1 - 0.077 13.1 4.2 0.14 12.2 4.2 1.5 1 0 0 1 1 1 0 Gti1/Pac2 family SpoIIP PF07454.11 CAR25740.1 - 0.083 12.3 8.8 0.13 11.7 8.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 CAR25740.1 - 0.11 12.7 8.1 0.22 11.7 8.1 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TMEM51 PF15345.6 CAR25740.1 - 0.13 12.1 9.1 0.22 11.4 9.1 1.5 1 0 0 1 1 1 0 Transmembrane protein 51 EOS1 PF12326.8 CAR25740.1 - 0.15 12.0 0.4 0.21 11.5 0.4 1.3 1 0 0 1 1 1 0 N-glycosylation protein DUF702 PF05142.12 CAR25740.1 - 0.22 12.0 8.6 0.47 10.9 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) GREB1 PF15782.5 CAR25740.1 - 0.3 8.2 13.0 0.39 7.8 13.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-3_zeta PF05091.12 CAR25740.1 - 0.3 10.0 15.1 0.43 9.5 15.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) OATP PF03137.20 CAR25740.1 - 0.36 9.1 5.8 0.56 8.4 5.8 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Tim54 PF11711.8 CAR25740.1 - 0.4 9.4 8.5 0.56 8.9 8.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pal1 PF08316.11 CAR25740.1 - 0.55 11.0 5.8 3.1 8.6 5.5 2.2 2 0 0 2 2 2 0 Pal1 cell morphology protein Presenilin PF01080.17 CAR25740.1 - 1.1 8.0 13.8 1.7 7.3 13.8 1.2 1 0 0 1 1 1 0 Presenilin RRM_3 PF08777.11 CAR25740.1 - 1.3 9.1 7.7 7.2 6.7 7.7 2.2 1 1 0 1 1 1 0 RNA binding motif OmpH PF03938.14 CAR25740.1 - 1.6 9.1 32.1 2.6 8.4 32.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lin-8 PF03353.15 CAR25740.1 - 1.6 8.2 19.0 2.8 7.4 19.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ABC2_membrane_2 PF12679.7 CAR25740.1 - 1.8 7.7 4.3 1.6 8.0 3.1 1.4 2 0 0 2 2 1 0 ABC-2 family transporter protein FAM60A PF15396.6 CAR25740.1 - 1.9 8.5 7.9 3.1 7.7 7.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A CLN3 PF02487.17 CAR25740.1 - 2 7.4 7.8 3 6.8 7.8 1.2 1 0 0 1 1 1 0 CLN3 protein Suf PF05843.14 CAR25740.1 - 2 8.3 16.2 4.6 7.1 16.2 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 CAR25740.1 - 3 7.8 19.1 5.2 7.1 19.1 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EIF4E-T PF10477.9 CAR25740.1 - 3.4 6.4 21.6 5.2 5.8 21.6 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Ndc1_Nup PF09531.10 CAR25740.1 - 4.1 6.0 13.2 5.7 5.5 13.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EMC3_TMCO1 PF01956.16 CAR25740.1 - 4.8 6.9 9.8 8.1 6.1 9.8 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FAM176 PF14851.6 CAR25740.1 - 4.9 6.8 6.5 8.9 6.0 6.5 1.3 1 0 0 1 1 1 0 FAM176 family RR_TM4-6 PF06459.12 CAR25740.1 - 4.9 6.9 12.0 7.6 6.3 12.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 CAR25740.1 - 5.1 6.9 13.0 8.9 6.1 13.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus Pex14_N PF04695.13 CAR25740.1 - 6.4 7.4 31.8 0.26 12.0 23.5 2.4 3 0 0 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Serinc PF03348.15 CAR25740.1 - 7.7 5.3 6.4 11 4.9 6.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PepSY_TM PF03929.16 CAR25740.1 - 7.9 6.0 8.2 13 5.3 8.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM region AAA_23 PF13476.6 CAR25740.1 - 9.4 6.7 17.4 14 6.1 17.4 1.3 1 0 0 1 1 1 0 AAA domain CobT PF06213.12 CAR25740.1 - 9.9 5.5 18.8 15 4.9 18.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PCRF PF03462.18 CAR25741.1 - 3.2e-54 183.8 1.1 4.7e-54 183.2 0.0 1.8 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CAR25741.1 - 8.4e-38 128.9 4.1 1.7e-37 127.9 4.1 1.5 1 0 0 1 1 1 1 RF-1 domain TraI_2B PF18340.1 CAR25741.1 - 0.031 14.4 0.0 0.092 12.8 0.0 1.8 1 0 0 1 1 1 0 DNA relaxase TraI 2B/2B-like domain Pkinase PF00069.25 CAR25742.1 - 1.2e-71 241.2 0.0 1.3e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25742.1 - 6.9e-31 107.5 0.0 9.2e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR25742.1 - 7.5e-06 26.0 0.1 1.2e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CAR25742.1 - 0.00088 18.7 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DAO PF01266.24 CAR25743.1 - 2e-51 175.7 0.0 2.3e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAR25743.1 - 1e-06 28.9 0.0 3.1e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CAR25743.1 - 0.00035 19.9 0.3 0.0018 17.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR25743.1 - 0.0043 17.6 0.5 0.021 15.4 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR25743.1 - 0.0059 15.9 0.5 0.022 14.0 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CAR25743.1 - 0.023 13.8 0.0 0.52 9.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 CAR25743.1 - 0.038 14.3 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.14 CAR25743.1 - 0.064 12.0 0.7 0.18 10.5 0.1 1.9 3 0 0 3 3 3 0 HI0933-like protein Amino_oxidase PF01593.24 CAR25743.1 - 0.17 11.1 0.0 2.1 7.6 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase K_oxygenase PF13434.6 CAR25743.1 - 0.18 10.9 0.2 16 4.5 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TPR_2 PF07719.17 CAR25744.1 - 9.2e-11 41.0 2.2 0.14 12.3 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAR25744.1 - 1.4e-07 31.2 1.1 0.0034 17.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAR25744.1 - 0.00045 19.9 1.1 0.27 11.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAR25744.1 - 0.0011 19.6 0.0 0.017 15.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAR25744.1 - 0.0012 19.1 0.0 0.026 14.8 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAR25744.1 - 0.019 15.0 0.2 4.5 7.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 CAR25744.1 - 0.047 14.4 0.3 27 5.6 0.0 4.1 4 0 0 4 4 4 0 Sel1 repeat TPR_14 PF13428.6 CAR25744.1 - 0.15 13.0 0.0 3.7 8.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 CAR25744.1 - 0.17 12.4 0.4 2 9.0 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.17 CAR25745.1 - 6.6e-106 355.0 24.0 7.7e-106 354.8 24.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HECT PF00632.25 CAR25746.1 - 1.5e-86 290.6 0.6 1.5e-86 290.6 0.6 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 CAR25747.1 - 1.3e-10 41.4 0.1 3e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 SPRY domain Homeodomain PF00046.29 CAR25748.1 - 9.5e-19 67.0 2.6 2.9e-18 65.5 2.7 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CAR25748.1 - 0.00099 19.0 0.5 0.0022 17.9 0.5 1.5 1 0 0 1 1 1 1 Homeobox KN domain L_protein_N PF15518.6 CAR25748.1 - 0.18 11.7 1.2 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 L protein N-terminus Aldedh PF00171.22 CAR25749.1 - 5.1e-164 546.2 0.0 5.7e-164 546.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 CAR25750.1 - 5.4e-168 559.3 0.5 6.1e-168 559.1 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3813 PF12758.7 CAR25750.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Cep3 PF16846.5 CAR25751.1 - 1.3e-214 713.4 16.1 1.5e-214 713.2 16.1 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Zn_clus PF00172.18 CAR25751.1 - 5.8e-07 29.5 9.4 1.2e-06 28.6 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mlh1_C PF16413.5 CAR25752.1 - 3e-82 276.0 0.1 4.5e-82 275.4 0.1 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CAR25752.1 - 2e-29 101.6 0.0 7.9e-29 99.8 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CAR25752.1 - 4.1e-11 42.8 0.0 8.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CAR25752.1 - 4.1e-05 24.1 0.0 8.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nse4_C PF08743.10 CAR25753.1 - 7.3e-31 106.3 1.6 8.1e-31 106.1 0.1 1.9 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 CAR25753.1 - 1.4e-13 50.8 3.9 5e-13 48.9 3.9 2.0 1 1 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Flu_M1_C PF08289.11 CAR25753.1 - 0.18 12.0 1.3 0.57 10.4 0.4 2.2 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain Peptidase_M22 PF00814.25 CAR25754.1 - 5e-69 233.0 0.0 6.1e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Mito_carr PF00153.27 CAR25755.1 - 9.7e-65 214.5 1.9 1.8e-24 85.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CAR25755.1 - 0.012 14.8 1.2 5.9 6.0 0.4 2.7 2 1 1 3 3 3 0 Gammaproteobacterial serine protease LNS2 PF08235.13 CAR25756.1 - 1.2e-91 306.2 0.0 5e-91 304.2 0.0 1.8 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CAR25756.1 - 5e-43 145.2 0.0 1.2e-42 144.0 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region WRNPLPNID PF15017.6 CAR25756.1 - 0.072 14.0 0.3 0.072 14.0 0.3 4.3 5 0 0 5 5 5 0 Putative WW-binding domain and destruction box Acid_phosphat_B PF03767.14 CAR25756.1 - 0.076 12.6 0.2 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) LisH PF08513.11 CAR25757.1 - 3e-07 30.2 0.3 4.6e-07 29.6 0.3 1.3 1 0 0 1 1 1 1 LisH Vezatin PF12632.7 CAR25758.1 - 0.002 17.6 14.0 0.17 11.2 14.0 3.3 1 1 0 1 1 1 1 Mysoin-binding motif of peroxisomes IPP-2 PF04979.14 CAR25758.1 - 0.11 13.2 4.9 0.23 12.2 4.9 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) UDPGP PF01704.18 CAR25759.1 - 6.9e-49 166.6 0.0 9.8e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CAR25759.1 - 0.19 12.1 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain PhoLip_ATPase_C PF16212.5 CAR25760.1 - 1.3e-72 244.6 21.2 1.3e-72 244.6 21.2 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAR25760.1 - 8.8e-23 79.8 1.4 8.8e-23 79.8 1.4 2.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CAR25760.1 - 2.8e-12 46.6 0.0 1.9e-11 43.9 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CAR25760.1 - 1.6e-11 44.9 0.0 0.00014 22.2 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CAR25760.1 - 6.9e-11 42.0 2.1 9.3e-10 38.3 0.1 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CAR25760.1 - 0.0011 18.7 0.7 0.0011 18.7 0.7 3.5 4 1 0 4 4 4 1 haloacid dehalogenase-like hydrolase DnaJ PF00226.31 CAR25761.1 - 4.3e-24 84.4 1.3 5.3e-24 84.1 0.6 1.6 2 0 0 2 2 2 1 DnaJ domain TrmK PF04816.12 CAR25761.1 - 0.024 14.2 0.1 0.035 13.7 0.1 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase DNA_pol_B PF00136.21 CAR25762.1 - 8.8e-143 476.3 0.8 1.2e-142 475.9 0.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CAR25762.1 - 3e-86 289.6 0.2 6.1e-86 288.6 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CAR25762.1 - 1.4e-17 63.9 5.4 2.8e-17 62.9 5.4 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CAR25762.1 - 2.6e-05 23.3 0.7 0.00057 18.9 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 CAR25762.1 - 0.002 18.2 0.9 0.028 14.4 0.7 2.9 2 1 0 2 2 2 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 CAR25762.1 - 0.0071 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.22 CAR25762.1 - 6.7 6.7 8.1 14 5.7 1.2 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 CAR25763.1 - 1.7e-70 237.4 0.0 2.3e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25763.1 - 3.3e-35 121.6 0.0 4.6e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CAR25763.1 - 9.1e-16 58.0 1.7 2.1e-15 56.8 1.7 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CAR25763.1 - 1.6e-07 31.6 0.1 3.9e-07 30.3 0.1 1.7 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 CAR25763.1 - 2.1e-05 23.5 0.0 4.9e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAR25763.1 - 4.6e-05 22.9 0.2 4.6e-05 22.9 0.2 1.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CAR25763.1 - 0.012 15.2 1.2 0.028 14.0 0.4 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 CAR25763.1 - 0.036 13.6 0.9 0.085 12.4 0.9 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL ATG16 PF08614.11 CAR25765.1 - 9.6e-11 42.3 9.5 9.6e-11 42.3 9.5 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) OmpH PF03938.14 CAR25765.1 - 0.0015 18.9 3.1 0.0017 18.7 3.1 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) TMF_TATA_bd PF12325.8 CAR25765.1 - 0.0018 18.5 5.3 0.0029 17.8 5.3 1.4 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 CAR25765.1 - 0.0047 17.4 5.7 0.006 17.1 5.7 1.2 1 0 0 1 1 1 1 Fez1 HIP1_clath_bdg PF16515.5 CAR25765.1 - 0.026 15.1 1.3 0.026 15.1 1.3 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2312 PF10073.9 CAR25765.1 - 0.041 13.5 0.1 0.041 13.5 0.1 2.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) DUF469 PF04320.14 CAR25765.1 - 0.11 13.3 1.9 1.9 9.4 1.9 2.2 1 1 0 1 1 1 0 Protein with unknown function (DUF469) KLRAQ PF10205.9 CAR25765.1 - 0.14 12.4 7.4 0.26 11.5 7.0 1.7 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF641 PF04859.12 CAR25765.1 - 0.21 12.0 5.0 0.2 12.0 3.4 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.8 CAR25765.1 - 0.38 10.8 12.7 1.5 8.9 3.7 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 CAR25765.1 - 0.69 8.9 6.2 0.77 8.8 6.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPD52 PF04201.15 CAR25765.1 - 1.5 8.4 6.3 2.9 7.5 1.6 2.1 1 1 1 2 2 2 0 Tumour protein D52 family Val_tRNA-synt_C PF10458.9 CAR25765.1 - 2.8 8.3 11.0 9.1 6.6 1.6 2.9 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm bZIP_1 PF00170.21 CAR25765.1 - 4.4 7.5 9.5 1.1 9.4 3.0 2.5 1 1 2 3 3 3 0 bZIP transcription factor DivIC PF04977.15 CAR25765.1 - 5.2 6.9 9.0 4.9 7.0 3.3 2.7 1 1 2 3 3 3 0 Septum formation initiator ArsA_ATPase PF02374.15 CAR25766.1 - 4.7e-116 387.2 0.0 5.5e-116 387.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CAR25766.1 - 1.6e-10 41.2 0.7 1.4e-09 38.1 0.0 2.6 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 CAR25766.1 - 1.4e-08 34.9 0.0 3.5e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CAR25766.1 - 0.00081 18.9 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 CAR25766.1 - 0.0013 18.3 1.7 0.0044 16.5 0.5 2.3 2 1 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 CAR25766.1 - 0.0024 17.5 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 CAR25766.1 - 0.019 14.9 0.2 0.046 13.6 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 CAR25766.1 - 0.02 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CAR25766.1 - 0.031 14.0 0.0 0.39 10.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 CAR25766.1 - 0.033 13.7 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 CAR25766.1 - 0.1 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Peptidase_C65 PF10275.9 CAR25767.1 - 0.016 14.7 1.5 0.016 14.7 1.5 1.8 2 0 0 2 2 2 0 Peptidase C65 Otubain Streptin-Immun PF11083.8 CAR25767.1 - 0.026 14.9 2.2 0.065 13.7 2.2 1.8 1 0 0 1 1 1 0 Lantibiotic streptin immunity protein SlyX PF04102.12 CAR25767.1 - 0.027 15.1 7.5 0.027 15.1 7.5 4.3 4 2 1 5 5 5 0 SlyX FlaC_arch PF05377.11 CAR25767.1 - 0.5 10.8 17.0 0.28 11.6 3.0 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) SOAR PF16533.5 CAR25767.1 - 1.4 9.0 16.0 0.52 10.3 3.5 2.8 2 0 0 2 2 2 0 STIM1 Orai1-activating region Macoilin PF09726.9 CAR25767.1 - 7.6 5.0 34.1 10 4.6 34.1 1.1 1 0 0 1 1 1 0 Macoilin family Ribosomal_S8 PF00410.19 CAR25768.1 - 1.5e-12 47.6 0.0 1.1e-11 44.8 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 Saw1 PF11561.8 CAR25768.1 - 0.11 12.1 0.2 0.17 11.4 0.1 1.5 2 0 0 2 2 2 0 Single strand annealing-weakened 1 EphA2_TM PF14575.6 CAR25769.1 - 0.15 13.0 0.0 0.32 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain zf-met PF12874.7 CAR25770.1 - 3.1e-06 27.4 1.9 6.4e-06 26.4 1.9 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CAR25770.1 - 0.031 14.6 2.2 0.067 13.5 2.2 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CK_II_beta PF01214.18 CAR25770.1 - 0.067 13.0 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Casein kinase II regulatory subunit zf-DBF PF07535.12 CAR25770.1 - 0.09 12.9 2.1 0.22 11.7 2.1 1.6 1 0 0 1 1 1 0 DBF zinc finger Imm70 PF15601.6 CAR25770.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 70 PNK3P PF08645.11 CAR25771.1 - 4.9e-39 133.6 0.0 5.6e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase RPN6_N PF18055.1 CAR25772.1 - 1.8e-38 131.5 3.1 1.8e-38 131.5 3.1 2.5 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CAR25772.1 - 5.5e-18 65.4 0.2 2.6e-17 63.3 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 CAR25772.1 - 4.6e-12 45.4 1.4 1e-11 44.3 0.4 2.2 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_15 PF13429.6 CAR25772.1 - 0.0028 16.9 2.7 0.0028 16.9 2.7 1.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAR25772.1 - 0.0039 17.8 0.2 1.5 9.5 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DDRGK PF09756.9 CAR25772.1 - 0.011 15.3 0.8 0.026 14.1 0.0 1.9 2 0 0 2 2 2 0 DDRGK domain TPR_19 PF14559.6 CAR25772.1 - 0.027 15.0 1.2 32 5.1 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 CAR25772.1 - 0.064 13.6 4.1 1.7 9.0 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4606 PF15379.6 CAR25772.1 - 0.35 11.1 2.4 3.3 8.0 0.8 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4606) Vps39_1 PF10366.9 CAR25772.1 - 0.38 11.1 5.4 0.16 12.3 1.8 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_7 PF13176.6 CAR25772.1 - 1.7 8.9 5.6 4.6 7.5 0.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAR25772.1 - 2 9.2 6.1 8.7 7.2 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat PMT PF02366.18 CAR25773.1 - 6.3e-81 271.6 17.7 6.3e-81 271.6 17.7 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CAR25773.1 - 1.1e-60 204.6 20.8 2.8e-60 203.3 20.8 1.7 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CAR25773.1 - 3.5e-46 157.4 0.0 6.1e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 MIR domain Nodulin-like PF06813.13 CAR25774.1 - 7.3e-12 45.3 5.5 1.6e-11 44.2 5.5 1.6 1 0 0 1 1 1 1 Nodulin-like Reticulon PF02453.17 CAR25774.1 - 0.088 12.8 0.7 0.41 10.6 0.4 2.1 2 0 0 2 2 2 0 Reticulon SRP14 PF02290.15 CAR25775.1 - 3.7e-24 84.9 0.4 3.7e-24 84.9 0.4 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein UBX PF00789.20 CAR25776.1 - 2.2e-16 59.8 0.0 3.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain Prenyltrans PF00432.21 CAR25777.1 - 1e-41 140.4 2.9 2.6e-12 46.2 0.0 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Crl PF07417.12 CAR25777.1 - 0.017 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Sigma factor-binding transcriptional regulator Crl SQHop_cyclase_C PF13243.6 CAR25777.1 - 0.051 12.7 0.1 4.8 6.2 0.0 2.3 1 1 1 2 2 2 0 Squalene-hopene cyclase C-terminal domain DUF2418 PF10332.9 CAR25779.1 - 3.1e-21 75.7 1.9 5.8e-21 74.8 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Nup35_RRM PF05172.13 CAR25780.1 - 6.5e-33 112.7 0.0 1.3e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CAR25780.1 - 0.0057 16.6 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ADH_zinc_N_2 PF13602.6 CAR25781.1 - 3.2e-14 54.1 0.0 6.5e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CAR25781.1 - 8.3e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR25781.1 - 6.3e-05 22.8 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain LUC7 PF03194.15 CAR25782.1 - 7.6e-61 205.9 5.5 8.6e-61 205.8 5.5 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Syntaxin_2 PF14523.6 CAR25782.1 - 0.14 12.6 3.4 0.44 11.0 0.7 2.5 1 1 1 2 2 2 0 Syntaxin-like protein adh_short PF00106.25 CAR25783.1 - 1.9e-19 69.9 0.0 3e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR25783.1 - 6.1e-06 26.0 0.0 9.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Noelin-1 PF12308.8 CAR25783.1 - 0.0019 18.2 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 Neurogenesis glycoprotein Alpha-mann_mid PF09261.11 CAR25783.1 - 0.054 13.6 0.1 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Alpha mannosidase middle domain Peptidase_M9_N PF08453.10 CAR25783.1 - 0.087 12.5 0.9 4.6 6.9 0.0 2.1 1 1 1 2 2 2 0 Peptidase family M9 N-terminal Peptidase_S24 PF00717.23 CAR25784.1 - 5.6e-06 26.2 0.1 5.1e-05 23.1 0.0 2.4 2 2 1 3 3 3 1 Peptidase S24-like Peptidase_S26 PF10502.9 CAR25784.1 - 0.0051 16.6 0.0 0.0092 15.8 0.0 1.5 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Ribophorin_II PF05817.14 CAR25785.1 - 2.4e-14 52.9 2.2 2.4e-14 52.9 2.2 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Osw5 PF17062.5 CAR25786.1 - 1.4e-30 105.2 12.5 1.8e-30 104.9 12.5 1.1 1 0 0 1 1 1 1 Outer spore wall 5 T5orf172 PF10544.9 CAR25788.1 - 3.9e-08 33.8 0.2 1.3e-06 28.9 0.2 2.1 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 CAR25788.1 - 1.4e-06 28.8 0.2 1.1e-05 26.0 0.2 2.1 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 DLH PF01738.18 CAR25789.1 - 7.5e-24 84.5 0.0 8.7e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CAR25789.1 - 1.2e-05 24.9 0.1 6.1e-05 22.6 0.0 2.1 2 1 0 2 2 2 1 Prolyl oligopeptidase family LIDHydrolase PF10230.9 CAR25789.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase PF07224.11 CAR25789.1 - 0.1 11.6 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase WD40 PF00400.32 CAR25790.1 - 1.1e-25 89.4 3.7 2.5e-06 28.1 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR25790.1 - 1.6e-08 34.7 0.2 1.1 9.6 0.2 4.6 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR25790.1 - 6.3e-06 26.2 0.1 0.2 11.5 0.1 3.1 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CAR25790.1 - 0.066 11.7 0.1 0.68 8.4 0.1 2.5 1 1 1 2 2 2 0 Cytochrome D1 heme domain 2-Hacid_dh_C PF02826.19 CAR25791.1 - 2.9e-38 131.0 0.0 1.7e-37 128.5 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAR25791.1 - 1.5e-17 63.5 0.1 2e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.20 CAR25791.1 - 0.036 14.1 0.2 0.98 9.5 0.0 2.6 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 CAR25792.1 - 3.6e-47 161.0 0.0 5.2e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR25792.1 - 7.5e-12 45.6 0.0 5.2e-11 42.9 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR25792.1 - 0.0075 15.6 0.0 2.1 7.5 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AMP-binding_C PF13193.6 CAR25792.1 - 0.028 15.4 0.0 0.27 12.2 0.0 2.5 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain HTH_psq PF05225.16 CAR25793.1 - 0.08 12.7 0.5 0.21 11.4 0.0 2.0 2 0 0 2 2 2 0 helix-turn-helix, Psq domain DEAD PF00270.29 CAR25794.1 - 1.5e-34 119.3 0.0 2.8e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR25794.1 - 8e-26 90.6 0.1 3.9e-24 85.1 0.2 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR25794.1 - 3.3e-08 33.7 0.0 6.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4844 PF16133.5 CAR25794.1 - 0.11 13.1 1.2 0.2 12.2 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) DSX_dimer PF08828.10 CAR25795.1 - 0.14 11.8 0.2 9.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Doublesex dimerisation domain DUF848 PF05852.11 CAR25795.1 - 0.15 12.1 8.1 0.054 13.6 4.8 1.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) YebO PF13974.6 CAR25795.1 - 1.8 8.7 11.1 6.2 7.0 1.8 3.5 3 0 0 3 3 3 0 YebO-like protein Ribosomal_S9 PF00380.19 CAR25796.1 - 2.9e-32 111.7 0.2 3.3e-32 111.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.18 CAR25797.1 - 2.8e-67 226.0 2.7 4.8e-67 225.3 2.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L13e E1_4HB PF16191.5 CAR25797.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Ribosomal_60s PF00428.19 CAR25798.1 - 1.3e-24 86.6 9.6 1.6e-24 86.3 9.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein WRNPLPNID PF15017.6 CAR25798.1 - 0.032 15.1 0.2 0.062 14.2 0.2 1.4 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF3824 PF12868.7 CAR25798.1 - 1.5 9.5 6.0 2.1 9.0 6.0 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Aminotran_3 PF00202.21 CAR25800.1 - 1.2e-62 211.9 0.0 1.5e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CAR25800.1 - 0.00058 19.2 0.0 0.0017 17.7 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CAR25800.1 - 0.1 11.7 0.0 0.55 9.3 0.0 2.1 2 1 1 3 3 3 0 Aminotransferase class I and II Pyridoxal_deC PF00282.19 CAR25800.1 - 0.12 11.1 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain TPP_enzyme_N PF02776.18 CAR25801.1 - 8.2e-29 100.4 0.0 1.3e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR25801.1 - 1.8e-20 73.1 0.0 3.5e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CAR25801.1 - 1.3e-14 54.2 0.1 2.4e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pkinase PF00069.25 CAR25802.1 - 4.4e-62 209.8 0.0 5.3e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25802.1 - 2.5e-26 92.5 0.0 3.6e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR25802.1 - 0.0082 16.1 0.1 0.022 14.7 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CAR25802.1 - 0.033 13.8 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ldh_1_N PF00056.23 CAR25803.1 - 1.5e-44 151.5 0.2 2.6e-44 150.7 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CAR25803.1 - 1.3e-43 148.8 0.0 2e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 CAR25803.1 - 3.7e-06 26.1 0.0 5.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CAR25803.1 - 0.018 15.5 0.0 0.039 14.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Arf PF00025.21 CAR25804.1 - 1.7e-42 144.8 0.0 2.1e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAR25804.1 - 8.6e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CAR25804.1 - 1.2e-12 47.6 1.0 2.8e-07 30.0 0.1 2.9 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CAR25804.1 - 2.1e-10 40.4 0.0 2.6e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CAR25804.1 - 3.1e-07 30.5 0.0 4.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR25804.1 - 4.6e-06 26.6 0.0 0.098 12.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CAR25804.1 - 1.1e-05 25.0 0.0 1.8e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CAR25804.1 - 1.7e-05 24.3 0.0 2.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR25804.1 - 0.00016 21.3 0.0 0.054 13.0 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CAR25804.1 - 0.0061 16.0 0.0 0.0077 15.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 CAR25804.1 - 0.025 14.2 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1_Xtn PF16897.5 CAR25804.1 - 0.18 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DRMBL PF07522.14 CAR25805.1 - 1.1e-25 90.0 0.6 2e-25 89.1 0.6 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CAR25805.1 - 0.017 14.6 0.1 0.031 13.8 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CAR25805.1 - 0.031 14.3 2.3 0.052 13.6 1.7 1.6 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily GATA PF00320.27 CAR25806.1 - 4.9e-15 54.8 2.3 1.1e-14 53.7 2.3 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF2031 PF09592.10 CAR25806.1 - 0.05 13.1 0.6 0.088 12.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) RE_AccI PF09545.10 CAR25806.1 - 0.18 10.7 0.0 0.26 10.2 0.0 1.1 1 0 0 1 1 1 0 AccI restriction endonuclease CLTH PF10607.9 CAR25807.1 - 1.4e-25 89.9 0.1 3.3e-25 88.7 0.1 1.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain HAD PF12710.7 CAR25807.1 - 0.091 13.2 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PLC-beta_C PF08703.10 CAR25808.1 - 0.013 15.5 0.4 0.025 14.6 0.4 1.4 1 0 0 1 1 1 0 PLC-beta C terminal UPF0052 PF01933.18 CAR25808.1 - 0.14 11.3 0.0 0.94 8.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0052 DUF1387 PF07139.11 CAR25809.1 - 0.44 10.2 6.9 0.51 10.0 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Macoilin PF09726.9 CAR25809.1 - 0.85 8.1 13.5 1 7.9 13.5 1.1 1 0 0 1 1 1 0 Macoilin family SRP1_TIP1 PF00660.17 CAR25810.1 - 4.9e-11 42.6 0.1 9.8e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 Seripauperin and TIP1 family Meiotic_rec114 PF03525.14 CAR25811.1 - 1.4e-06 27.6 0.2 1.4e-06 27.6 0.2 2.1 2 1 0 2 2 2 1 Meiotic recombination protein rec114 HTH_Tnp_Tc3_2 PF01498.18 CAR25811.1 - 0.21 11.8 1.7 15 5.9 0.2 2.8 3 0 0 3 3 3 0 Transposase NFACT-R_1 PF05670.13 CAR25812.1 - 8.3e-33 113.3 0.0 1.7e-32 112.3 0.0 1.5 2 0 0 2 2 2 1 NFACT protein RNA binding domain CAF1C_H4-bd PF12265.8 CAR25813.1 - 9e-16 57.9 0.2 4.8e-15 55.6 0.1 2.3 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CAR25813.1 - 1.1e-10 41.9 7.8 0.0012 19.6 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR25813.1 - 1.4e-07 31.7 0.9 0.0042 17.4 0.1 3.6 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RIC1 PF07064.13 CAR25814.1 - 1.2e-16 60.9 2.8 3.2e-16 59.5 2.8 1.8 1 1 0 1 1 1 1 RIC1 COX6B PF02297.17 CAR25815.1 - 2e-20 72.8 4.5 2.3e-20 72.6 4.5 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 CAR25815.1 - 0.11 12.6 1.8 0.16 12.0 1.8 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Hydrolase PF00702.26 CAR25816.1 - 8e-11 42.6 0.0 1.1e-10 42.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAR25816.1 - 1.2e-09 38.5 0.0 2.3e-09 37.6 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR25816.1 - 2.4e-07 30.7 0.0 4.8e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HATPase_c_3 PF13589.6 CAR25817.1 - 6.5e-11 42.2 0.5 1.7e-10 40.9 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 CAR25817.1 - 5.6e-08 32.5 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 CAR25817.1 - 4.8e-05 23.8 0.0 0.00014 22.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3747 PF12565.8 CAR25818.1 - 0.11 11.8 0.0 0.74 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3747) Y_Y_Y PF07495.13 CAR25818.1 - 0.22 11.5 2.5 0.93 9.5 0.9 2.8 2 0 0 2 2 2 0 Y_Y_Y domain Nramp PF01566.18 CAR25819.1 - 1.4e-93 313.8 16.7 1.8e-93 313.4 16.7 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Bromodomain PF00439.25 CAR25820.1 - 1.5e-07 31.4 0.8 4.9e-07 29.7 0.3 2.2 2 1 0 2 2 2 1 Bromodomain RNA_pol_Rpc4 PF05132.14 CAR25820.1 - 0.024 15.0 1.4 0.044 14.2 1.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 CAR25820.1 - 0.41 8.9 7.6 0.59 8.4 7.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CAR25820.1 - 7.5 5.2 6.8 11 4.7 6.8 1.2 1 0 0 1 1 1 0 Presenilin HA2 PF04408.23 CAR25821.1 - 1.3e-28 99.4 2.9 2.9e-28 98.3 0.0 3.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CAR25821.1 - 2.7e-14 53.3 0.0 7.1e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAR25821.1 - 1.4e-12 47.9 0.1 6.6e-11 42.5 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAR25821.1 - 7.4e-08 32.3 0.0 2.5e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR25821.1 - 0.00054 20.2 1.0 0.0019 18.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CAR25821.1 - 0.012 16.0 0.0 0.034 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CAR25821.1 - 0.013 14.9 0.0 0.04 13.3 0.0 1.8 1 0 0 1 1 1 0 KaiC HTH_37 PF13744.6 CAR25821.1 - 0.017 15.0 0.7 0.081 12.9 0.7 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain T2SSE PF00437.20 CAR25821.1 - 0.029 13.5 0.1 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.16 CAR25821.1 - 0.035 13.6 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 CAR25821.1 - 0.042 13.6 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MOZ_SAS PF01853.18 CAR25822.1 - 1.8e-56 190.6 1.6 2.5e-56 190.2 1.6 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CAR25822.1 - 4.3e-09 35.8 3.9 7.5e-07 28.7 2.0 2.8 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CAR25822.1 - 0.0038 17.6 0.0 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAR25822.1 - 0.013 15.7 0.0 0.043 14.1 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family SNF2_N PF00176.23 CAR25823.1 - 1.6e-66 224.5 0.1 2.2e-66 224.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 CAR25823.1 - 6.9e-16 58.0 0.0 1.3e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 CAR25823.1 - 7.3e-15 55.3 0.0 1.9e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 CAR25823.1 - 4.6e-08 33.3 11.9 8.7e-08 32.4 11.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CAR25823.1 - 8.1e-06 25.6 10.1 1.4e-05 24.9 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 CAR25823.1 - 5.7e-05 23.2 0.0 0.00025 21.1 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 CAR25823.1 - 6.8e-05 22.7 12.7 0.00013 21.8 12.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CAR25823.1 - 0.00029 20.6 14.2 0.00058 19.7 14.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR25823.1 - 0.00041 20.3 9.5 0.00086 19.3 9.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR25823.1 - 0.073 12.9 12.5 0.15 11.9 12.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn-ribbon_8 PF09723.10 CAR25823.1 - 0.12 12.5 1.7 0.32 11.2 1.7 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-ANAPC11 PF12861.7 CAR25823.1 - 0.18 11.9 2.9 0.4 10.8 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CAR25823.1 - 0.35 10.8 9.5 0.63 9.9 9.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CAR25823.1 - 0.54 10.6 7.5 1.3 9.4 7.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CAR25823.1 - 0.72 9.7 9.9 1.6 8.6 9.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CAR25823.1 - 1.8 8.8 12.4 3.8 7.7 12.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4129 PF13559.6 CAR25824.1 - 0.21 11.9 0.0 0.4 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) DUF3827 PF12877.7 CAR25824.1 - 0.31 9.4 4.3 0.46 8.8 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MIF4G_like_2 PF09090.11 CAR25825.1 - 2.1e-54 184.8 3.8 2.5e-47 161.6 0.3 2.6 2 1 1 3 3 3 2 MIF4G like MIF4G_like PF09088.11 CAR25825.1 - 2.1e-53 180.9 1.9 4.3e-53 179.9 0.8 2.1 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.19 CAR25825.1 - 5.1e-09 36.1 4.3 1.2e-08 34.8 2.9 2.5 2 0 0 2 2 2 1 MIF4G domain BLOC1_2 PF10046.9 CAR25825.1 - 0.51 10.7 2.2 1.4 9.3 0.3 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pkr1 PF08636.10 CAR25827.1 - 1.7e-29 101.8 8.1 2.2e-29 101.4 8.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 PufQ PF05398.11 CAR25827.1 - 0.0075 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 PufQ cytochrome subunit DUF4834 PF16118.5 CAR25827.1 - 0.012 16.5 0.4 0.012 16.5 0.4 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) Peroxin-13_N PF04088.13 CAR25827.1 - 0.015 15.6 0.3 0.022 15.1 0.3 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Ni_hydr_CYTB PF01292.20 CAR25827.1 - 0.021 14.5 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 TMEM192 PF14802.6 CAR25827.1 - 0.033 13.3 0.2 0.051 12.7 0.2 1.3 1 0 0 1 1 1 0 TMEM192 family O-antigen_lig PF13425.6 CAR25827.1 - 0.035 12.9 0.0 0.036 12.9 0.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein SPATIAL PF15256.6 CAR25827.1 - 0.04 14.3 1.5 0.04 14.3 1.5 1.5 2 0 0 2 2 2 0 SPATIAL FAM176 PF14851.6 CAR25827.1 - 0.04 13.6 0.2 0.05 13.3 0.2 1.2 1 0 0 1 1 1 0 FAM176 family Menin PF05053.13 CAR25827.1 - 0.052 11.9 1.9 0.055 11.8 1.9 1.0 1 0 0 1 1 1 0 Menin DUF4131 PF13567.6 CAR25827.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Mem_trans PF03547.18 CAR25827.1 - 0.11 10.9 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Membrane transport protein Kei1 PF08552.11 CAR25827.1 - 0.23 11.3 4.6 0.44 10.4 4.6 1.5 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Ribosomal_L15e PF00827.17 CAR25830.1 - 1.2e-87 292.6 12.2 1.4e-87 292.4 12.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 AICARFT_IMPCHas PF01808.18 CAR25831.1 - 3.6e-93 312.3 0.0 5.8e-93 311.6 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CAR25831.1 - 2e-24 85.6 0.2 4.1e-24 84.6 0.0 1.7 2 0 0 2 2 2 1 MGS-like domain Dis3l2_C_term PF17877.1 CAR25831.1 - 0.055 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal zf-C3HC4_3 PF13920.6 CAR25832.1 - 1.2e-08 34.7 11.6 2.2e-08 33.8 11.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR25832.1 - 0.097 12.5 11.8 0.19 11.6 11.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Transket_pyr PF02779.24 CAR25833.1 - 1.1e-45 155.5 0.0 1.7e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CAR25833.1 - 7.8e-39 132.4 0.3 2.3e-38 130.8 0.3 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain Acatn PF13000.7 CAR25834.1 - 1.1e-274 912.1 8.3 1.3e-274 911.9 8.3 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Scs3p PF10261.9 CAR25835.1 - 4.5e-66 222.8 5.4 6.2e-66 222.4 5.4 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Med31 PF05669.12 CAR25836.1 - 1.8e-24 85.6 0.7 2.1e-24 85.4 0.7 1.2 1 0 0 1 1 1 1 SOH1 Hexapep PF00132.24 CAR25837.1 - 4.3e-12 45.2 20.7 8.9e-07 28.4 2.0 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) W2 PF02020.18 CAR25837.1 - 1e-10 41.6 23.9 5e-10 39.4 22.3 2.7 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 CAR25837.1 - 1.7e-07 31.1 0.0 4e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Fucokinase PF07959.12 CAR25837.1 - 7.6e-06 25.1 1.0 1.1e-05 24.5 0.5 1.5 2 0 0 2 2 2 1 L-fucokinase NTP_transf_3 PF12804.7 CAR25837.1 - 0.00081 19.8 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CAR25837.1 - 0.0037 17.0 18.7 0.0039 16.9 4.8 3.5 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CAR25837.1 - 0.042 12.0 11.8 0.0055 14.9 6.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) Ras PF00071.22 CAR25838.1 - 1.4e-50 171.1 0.0 1.6e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR25838.1 - 2.8e-18 66.3 0.0 3.9e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR25838.1 - 8.5e-07 28.6 0.0 1.1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Siah-Interact_N PF09032.11 CAR25838.1 - 0.06 13.7 0.4 0.097 13.0 0.4 1.2 1 0 0 1 1 1 0 Siah interacting protein, N terminal Cpn60_TCP1 PF00118.24 CAR25839.1 - 6.4e-154 513.2 15.2 7.2e-154 513.0 15.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MRP-S31 PF15433.6 CAR25839.1 - 0.2 11.3 0.1 0.36 10.4 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Fungal_trans_2 PF11951.8 CAR25840.1 - 4.2e-13 48.9 0.4 4.2e-13 48.9 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR25840.1 - 5.8e-08 32.7 12.3 1e-07 31.9 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc7_N PF15402.6 CAR25840.1 - 0.00067 18.1 6.6 0.00067 18.1 6.6 3.1 2 1 0 3 3 3 1 N-terminus of kinetochore NMS complex subunit Spc7 MecA PF05389.12 CAR25840.1 - 1.2 8.7 4.5 0.63 9.6 0.7 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Aha1_N PF09229.11 CAR25841.1 - 4.8e-35 120.7 0.4 1.4e-34 119.2 0.1 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CAR25841.1 - 6.9e-12 45.7 0.1 1.3e-11 44.8 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF515 PF04415.12 CAR25841.1 - 0.04 12.3 2.8 0.063 11.7 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Hydrolase_6 PF13344.6 CAR25842.1 - 4.9e-23 81.2 0.0 1.2e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR25842.1 - 3.1e-13 49.6 0.0 1.2e-12 47.7 0.0 2.1 2 1 0 2 2 2 1 HAD-hyrolase-like zf-C2H2 PF00096.26 CAR25843.1 - 2.2e-07 30.9 18.0 7.7e-05 22.9 1.7 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR25843.1 - 1.7e-06 28.1 10.2 8.9e-06 25.9 6.1 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR25843.1 - 0.00036 21.1 15.4 0.036 14.9 1.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CAR25843.1 - 0.011 16.1 4.6 1.2 9.6 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CAR25843.1 - 0.051 13.9 2.5 0.67 10.3 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3439 PF11921.8 CAR25843.1 - 0.99 9.4 8.5 3.4 7.6 8.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-C2H2_6 PF13912.6 CAR25843.1 - 4.7 7.3 13.5 0.49 10.5 1.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Rad9_Rad53_bind PF08605.10 CAR25844.1 - 9.8e-41 139.0 0.2 2.4e-40 137.7 0.2 1.7 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 CAR25844.1 - 3.7e-07 30.4 0.8 1.5e-06 28.5 0.1 2.6 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CAR25844.1 - 0.00083 19.7 0.9 0.071 13.5 0.0 3.2 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CAR25844.1 - 0.076 12.9 2.8 0.093 12.6 0.0 2.5 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain Septin PF00735.18 CAR25846.1 - 7.3e-71 238.7 0.2 1e-70 238.2 0.2 1.2 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 CAR25846.1 - 0.011 15.6 0.0 0.71 9.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 CAR25846.1 - 0.018 15.1 0.5 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Dynamin family AAA_24 PF13479.6 CAR25846.1 - 0.14 11.9 0.0 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Glutaredoxin2_C PF04399.13 CAR25846.1 - 0.15 11.9 0.3 1 9.2 0.2 2.3 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain MMR_HSR1 PF01926.23 CAR25846.1 - 0.17 12.0 0.0 0.54 10.4 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF2587 PF10759.9 CAR25847.1 - 0.045 13.3 0.2 0.081 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) F-box-like PF12937.7 CAR25848.1 - 0.00096 19.0 0.1 0.0018 18.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CAR25848.1 - 0.0015 18.4 0.4 0.0027 17.6 0.4 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 CAR25848.1 - 0.0057 16.5 1.5 0.0091 15.9 0.1 2.1 2 0 0 2 2 2 1 F-box domain PRKCSH-like PF12999.7 CAR25849.1 - 4e-39 134.2 1.2 1.1e-38 132.8 1.2 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CAR25849.1 - 5.3e-18 65.2 6.2 1.5e-16 60.4 6.2 2.8 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein DIT1_PvcA PF05141.12 CAR25849.1 - 3.1e-05 23.6 0.8 3.1e-05 23.6 0.8 1.9 2 0 0 2 2 2 1 Pyoverdine/dityrosine biosynthesis protein PRKCSH PF07915.13 CAR25849.1 - 0.00087 20.2 0.2 0.0029 18.6 0.2 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Golgin_A5 PF09787.9 CAR25849.1 - 0.0096 15.4 1.5 0.0096 15.4 1.5 2.7 2 1 2 4 4 4 1 Golgin subfamily A member 5 Hemerythrin PF01814.23 CAR25849.1 - 0.016 15.9 4.4 0.27 11.9 0.2 3.7 3 1 1 4 4 4 0 Hemerythrin HHE cation binding domain Ldl_recept_a PF00057.18 CAR25849.1 - 0.04 14.1 15.6 0.42 10.9 5.6 2.8 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A SMC_ScpB PF04079.16 CAR25849.1 - 0.049 13.2 1.1 3.7 7.2 0.1 2.4 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB Phage_connect_1 PF05135.13 CAR25849.1 - 0.053 14.0 0.1 0.053 14.0 0.1 3.1 4 1 0 4 4 4 0 Phage gp6-like head-tail connector protein DUF2048 PF09752.9 CAR25849.1 - 0.14 11.2 0.1 0.19 10.8 0.1 1.4 1 0 0 1 1 1 0 Abhydrolase domain containing 18 TPR_MLP1_2 PF07926.12 CAR25849.1 - 0.48 10.5 13.8 0.42 10.7 2.6 3.4 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein RNase_E_G PF10150.9 CAR25849.1 - 0.5 9.7 5.6 5.1 6.4 0.8 2.5 2 0 0 2 2 2 0 Ribonuclease E/G family KinB_sensor PF16767.5 CAR25849.1 - 1 9.9 4.8 11 6.5 0.2 2.8 2 1 1 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB LemA PF04011.12 CAR25849.1 - 1.2 9.0 5.1 6.4 6.6 0.5 2.9 2 1 0 2 2 2 0 LemA family Mod_r PF07200.13 CAR25849.1 - 2 8.5 12.2 8.1 6.5 3.8 3.9 2 2 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Svf1_C PF17187.4 CAR25850.1 - 2.1e-39 135.0 0.8 6.6e-39 133.4 0.8 1.8 1 1 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 CAR25850.1 - 1.4e-38 132.5 0.2 1.8e-36 125.6 0.0 2.1 2 0 0 2 2 2 2 Svf1-like N-terminal lipocalin domain DUF3194 PF11419.8 CAR25850.1 - 0.0086 16.4 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3194) CRF1 PF10380.9 CAR25852.1 - 1e-35 122.5 3.0 1e-35 122.5 3.0 4.1 4 1 0 4 4 4 1 Transcription factor CRF1 Utp13 PF08625.11 CAR25853.1 - 2e-48 163.9 1.4 3.3e-48 163.2 1.4 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 CAR25853.1 - 2.6e-41 138.8 22.0 2.4e-05 25.0 0.0 10.6 11 0 0 11 11 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR25853.1 - 8.9e-23 80.4 5.5 0.0011 19.2 0.0 7.8 5 2 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAR25853.1 - 1.1e-08 34.7 3.6 0.00074 18.9 0.1 4.2 2 2 3 5 5 5 2 WD40-like domain Nup160 PF11715.8 CAR25853.1 - 1.9e-07 30.1 7.0 0.21 10.2 1.4 6.2 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CAR25853.1 - 0.00017 20.5 3.0 0.026 13.3 0.1 3.3 1 1 2 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.16 CAR25853.1 - 0.0017 16.9 0.1 2.4 6.6 0.0 3.3 3 1 1 4 4 4 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 CAR25853.1 - 0.0021 17.2 1.5 0.091 11.8 0.0 2.4 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 CAR25853.1 - 0.026 14.4 0.5 2.6 7.9 0.1 3.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Utp12 PF04003.12 CAR25853.1 - 0.03 14.6 0.6 0.065 13.5 0.6 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Ntox33 PF15533.6 CAR25853.1 - 0.12 12.9 0.2 0.7 10.4 0.1 2.1 2 0 0 2 2 2 0 Bacterial toxin 33 DUF2750 PF11042.8 CAR25853.1 - 0.49 10.5 4.2 1.7 8.8 0.4 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2750) Rsa3 PF14615.6 CAR25854.1 - 7.5e-18 63.8 0.3 1.3e-17 63.1 0.3 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 TerD PF02342.18 CAR25854.1 - 0.0031 17.0 0.2 0.005 16.3 0.2 1.2 1 0 0 1 1 1 1 TerD domain Fusion_gly PF00523.18 CAR25854.1 - 0.0045 15.3 0.8 0.0057 14.9 0.8 1.1 1 0 0 1 1 1 1 Fusion glycoprotein F0 NAM-associated PF14303.6 CAR25854.1 - 0.38 11.4 13.7 0.5 11.1 13.7 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain VIT1 PF01988.19 CAR25855.1 - 2.1e-62 210.8 0.4 2.7e-62 210.5 0.4 1.1 1 0 0 1 1 1 1 VIT family DUF3185 PF11381.8 CAR25855.1 - 0.02 14.9 3.3 0.069 13.2 3.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) Histone PF00125.24 CAR25856.1 - 1.3e-19 70.9 2.9 1.6e-19 70.6 2.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR25856.1 - 1.9e-05 24.8 0.1 4e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CAR25856.1 - 0.0044 17.5 0.0 0.0075 16.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone_H2A_C PF16211.5 CAR25857.1 - 1.4e-20 72.7 1.6 2.3e-20 72.0 1.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CAR25857.1 - 8.7e-18 64.9 0.0 1.2e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR25857.1 - 1.8e-06 28.1 0.0 2.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Trypan_PARP PF05887.11 CAR25858.1 - 5 7.1 18.0 1.8 8.6 13.4 2.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SIR4_SID PF16991.5 CAR25859.1 - 1.4e-32 113.0 0.1 1.4e-32 113.0 0.1 5.2 4 2 3 7 7 7 1 Sir4 SID domain CobT_C PF11775.8 CAR25859.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Thg1 PF04446.12 CAR25860.1 - 0.028 14.5 0.5 8.7 6.4 0.0 2.5 2 0 0 2 2 2 0 tRNAHis guanylyltransferase DUF3573 PF12097.8 CAR25860.1 - 3.2 6.5 7.1 1.4 7.7 3.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) Atg14 PF10186.9 CAR25860.1 - 3.5 6.6 20.7 0.52 9.3 3.6 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 CAR25860.1 - 8.8 7.0 17.6 0.28 11.8 2.2 4.7 6 0 0 6 6 6 0 SlyX CFIA_Pcf11 PF11526.8 CAR25861.1 - 3.5e-26 91.5 1.0 3.5e-26 91.5 1.0 2.5 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 DUF1644 PF07800.12 CAR25861.1 - 0.078 13.0 2.5 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) AIF_C PF14721.6 CAR25861.1 - 0.079 13.3 2.3 0.19 12.1 2.3 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term V_ATPase_I PF01496.19 CAR25861.1 - 0.11 10.4 7.9 0.15 9.9 7.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C2H2_4 PF13894.6 CAR25861.1 - 0.19 12.7 1.2 13 6.9 0.1 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 CAR25861.1 - 0.23 11.9 1.8 4.7 7.8 0.0 2.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain ZYG-11_interact PF05884.12 CAR25861.1 - 0.43 10.0 4.5 0.71 9.2 4.5 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 Exonuc_VII_L PF02601.15 CAR25861.1 - 0.48 9.9 12.0 0.81 9.2 12.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit EIF4E-T PF10477.9 CAR25861.1 - 0.59 8.9 16.5 0.93 8.2 16.5 1.3 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF4175 PF13779.6 CAR25861.1 - 1.2 6.9 27.9 1.6 6.6 27.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CTU2 PF10288.9 CAR25861.1 - 2.1 8.6 9.5 4.7 7.5 5.0 3.0 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-H2C2_2 PF13465.6 CAR25861.1 - 7.6 7.2 7.8 30 5.3 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain LMBR1 PF04791.16 CAR25861.1 - 9.3 5.0 7.5 13 4.5 7.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Mito_carr PF00153.27 CAR25862.1 - 6.5e-34 115.7 1.2 1e-15 57.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.24 CAR25863.1 - 9.1e-100 334.6 17.9 1.1e-99 334.4 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR25863.1 - 6.8e-29 100.9 45.1 4.4e-28 98.2 22.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CAR25863.1 - 0.067 11.5 5.0 0.022 13.1 0.7 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DNA_binding_1 PF01035.20 CAR25864.1 - 1.2e-26 92.6 0.1 1.8e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_4 PF02390.17 CAR25865.1 - 1.5e-61 206.9 0.1 2.2e-61 206.3 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CAR25865.1 - 0.00023 21.8 0.0 0.0017 19.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR25865.1 - 0.00029 20.7 0.1 0.00089 19.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CAR25865.1 - 0.0019 17.8 0.0 0.012 15.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CAR25865.1 - 0.0025 18.5 0.0 0.017 15.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR25865.1 - 0.027 13.8 0.0 0.078 12.3 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DOT1 PF08123.13 CAR25865.1 - 0.051 13.1 0.0 0.2 11.2 0.0 1.8 1 1 1 2 2 2 0 Histone methylation protein DOT1 Ribosomal_L10 PF00466.20 CAR25866.1 - 6.8e-11 42.2 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Peptidase_C97 PF05903.14 CAR25867.1 - 0.025 14.4 0.1 0.04 13.8 0.1 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain Luciferase_3H PF10284.9 CAR25867.1 - 0.073 13.2 1.1 0.22 11.7 0.2 2.1 2 0 0 2 2 2 0 Luciferase helical bundle domain 5_3_exonuc PF01367.20 CAR25867.1 - 0.089 13.4 0.5 0.37 11.4 0.5 2.1 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF3767 PF12597.8 CAR25868.1 - 1.4e-37 127.5 0.1 2e-37 127.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) CPP1-like PF11833.8 CAR25868.1 - 0.064 12.9 0.3 0.092 12.4 0.2 1.5 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Sel1 PF08238.12 CAR25869.1 - 4.8e-36 122.4 26.6 1.5e-09 38.2 0.3 8.3 7 2 0 7 7 7 6 Sel1 repeat Phospholip_A2_3 PF09056.11 CAR25869.1 - 0.039 14.6 2.8 2.5 8.8 0.6 2.6 2 0 0 2 2 2 0 Prokaryotic phospholipase A2 Med3 PF11593.8 CAR25869.1 - 0.054 12.7 3.1 0.078 12.2 3.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TPR_6 PF13174.6 CAR25869.1 - 6.4 7.6 12.1 71 4.4 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 CAR25870.1 - 4.2e-72 243.3 0.0 5.2e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CAR25870.1 - 1.9e-08 33.3 0.0 3.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CAR25870.1 - 4.5e-05 22.6 0.1 0.00011 21.3 0.1 1.6 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CAR25870.1 - 0.0011 18.3 0.3 0.51 9.6 0.1 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Preseq_ALAS PF09029.10 CAR25870.1 - 0.0057 17.1 0.3 0.012 16.1 0.3 1.5 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Reticulon PF02453.17 CAR25871.1 - 1.9e-34 118.9 2.2 2.7e-34 118.4 2.2 1.2 1 0 0 1 1 1 1 Reticulon Aconitase PF00330.20 CAR25872.1 - 5.7e-107 358.6 0.1 3e-105 352.9 0.1 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CAR25872.1 - 1.3e-28 100.0 0.0 2.6e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Porphobil_deam PF01379.20 CAR25873.1 - 1.6e-74 249.9 0.0 2e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CAR25873.1 - 4e-20 72.0 0.3 6.9e-20 71.2 0.3 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain ATF7IP_BD PF16788.5 CAR25873.1 - 0.14 12.3 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 ATF-interacting protein binding domain Na_Ca_ex PF01699.24 CAR25875.1 - 3.8e-48 163.3 38.3 5e-28 98.0 10.1 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Flavokinase PF01687.17 CAR25876.1 - 4e-26 91.5 0.0 5.2e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase GLE1 PF07817.13 CAR25877.1 - 2.1e-90 302.3 0.9 3.8e-90 301.5 0.9 1.4 1 0 0 1 1 1 1 GLE1-like protein CDC45 PF02724.14 CAR25877.1 - 0.0029 16.0 15.6 0.0045 15.4 15.6 1.2 1 0 0 1 1 1 1 CDC45-like protein CAF-1_p150 PF11600.8 CAR25877.1 - 0.0047 16.6 34.4 0.011 15.4 34.4 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MAP7 PF05672.11 CAR25877.1 - 0.0093 15.7 39.1 0.019 14.7 39.1 1.5 1 0 0 1 1 1 1 MAP7 (E-MAP-115) family DUF1682 PF07946.14 CAR25877.1 - 0.092 11.9 18.8 0.17 11.1 18.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.12 CAR25877.1 - 0.41 10.4 15.8 0.85 9.4 15.8 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CAR25877.1 - 3.6 6.2 14.9 5.8 5.6 14.9 1.3 1 0 0 1 1 1 0 Presenilin Asp-B-Hydro_N PF05279.11 CAR25877.1 - 9.5 6.2 23.7 0.78 9.8 19.1 1.6 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Ribosomal_L5_C PF00673.21 CAR25878.1 - 2e-28 98.4 0.0 1.7e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CAR25878.1 - 1.5e-12 47.6 0.0 3.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 MRP-S33 PF08293.11 CAR25879.1 - 6.3e-32 109.7 0.0 7.5e-32 109.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Gpi1 PF05024.15 CAR25880.1 - 1.1e-59 201.7 16.1 1.1e-59 201.7 16.1 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Ion_trans PF00520.31 CAR25881.1 - 2.4e-114 380.7 107.4 2.3e-40 138.4 14.8 5.2 4 1 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 CAR25881.1 - 5.6e-06 25.3 4.0 5.6e-06 25.3 4.0 9.4 8 2 1 10 10 10 5 Polycystin cation channel EF-hand_1 PF00036.32 CAR25881.1 - 0.028 14.0 0.0 0.15 11.7 0.0 2.3 2 0 0 2 2 2 0 EF hand GPHH PF16905.5 CAR25881.1 - 0.035 13.9 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_7 PF13499.6 CAR25881.1 - 0.038 14.4 0.0 0.21 12.1 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair GDPD PF03009.17 CAR25882.1 - 3.8e-82 275.9 0.2 6.8e-82 275.1 0.2 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 CAR25882.1 - 2.2e-25 89.1 0.0 1e-11 45.3 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) SPX PF03105.19 CAR25882.1 - 1.9e-21 77.5 22.9 2.4e-12 47.5 2.7 4.4 3 1 1 4 4 4 3 SPX domain Ank_4 PF13637.6 CAR25882.1 - 9.1e-16 58.0 0.1 3.4e-07 30.7 0.0 4.5 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAR25882.1 - 6.7e-15 55.0 0.2 0.017 15.4 0.0 5.1 2 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAR25882.1 - 4.8e-13 48.0 2.6 1.6 9.5 0.0 7.5 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 CAR25882.1 - 2.1e-12 46.9 6.8 0.22 12.1 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat ABC1 PF03109.16 CAR25883.1 - 1.5e-19 70.3 0.0 5.3e-19 68.5 0.0 1.8 1 1 0 1 1 1 1 ABC1 family Arf PF00025.21 CAR25884.1 - 5.3e-75 250.7 0.1 6e-75 250.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAR25884.1 - 1.2e-15 57.7 0.0 1.7e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAR25884.1 - 1.3e-11 44.3 0.0 1.5e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CAR25884.1 - 1.3e-10 41.1 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CAR25884.1 - 3.6e-10 39.5 0.2 3.7e-06 26.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CAR25884.1 - 2.7e-09 36.7 0.0 3.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR25884.1 - 0.00015 21.8 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR25884.1 - 0.00023 20.7 0.2 0.0019 17.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CAR25884.1 - 0.00062 20.3 0.3 0.0024 18.4 0.3 1.7 1 1 0 1 1 1 1 ABC transporter MeaB PF03308.16 CAR25884.1 - 0.0023 17.0 0.9 0.096 11.7 0.4 2.7 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CAR25884.1 - 0.04 14.5 0.1 0.098 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 CAR25884.1 - 0.065 12.9 0.3 0.69 9.5 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 CAR25884.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain EBV-NA3 PF05009.12 CAR25885.1 - 0.0035 16.9 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PDH PF02153.17 CAR25886.1 - 2.5e-13 49.6 0.1 3.5e-13 49.2 0.1 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 CAR25886.1 - 4e-05 24.1 0.0 8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CAR25886.1 - 4e-05 23.8 0.0 8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 CAR25886.1 - 0.0001 21.7 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CAR25886.1 - 0.00026 20.7 0.0 0.00057 19.6 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CAR25886.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 CAR25886.1 - 0.016 15.5 0.0 0.04 14.2 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 CAR25886.1 - 0.027 14.1 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 CAR25886.1 - 0.03 14.4 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rossmann-like PF10727.9 CAR25886.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain EccE PF11203.8 CAR25886.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE Ureidogly_lyase PF04115.12 CAR25887.1 - 3.4e-50 170.4 0.0 4.1e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase TPR_10 PF13374.6 CAR25888.1 - 0.011 15.5 0.5 0.02 14.8 0.5 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Rpp20 PF12328.8 CAR25889.1 - 2e-27 95.8 1.2 4.8e-25 88.1 1.2 2.0 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 CAR25889.1 - 3.8e-09 36.2 0.1 5.7e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Alba Ribosomal_L18 PF17135.4 CAR25889.1 - 0.034 13.6 0.1 0.039 13.4 0.1 1.1 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Pex24p PF06398.11 CAR25890.1 - 1.6e-40 139.2 8.7 2.1e-40 138.8 8.7 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3810 PF12725.7 CAR25890.1 - 0.069 12.5 0.7 0.1 11.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Oxidored-like PF09791.9 CAR25891.1 - 3.8e-25 87.3 1.1 6.9e-25 86.5 1.1 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5383 PF17355.2 CAR25891.1 - 0.33 11.3 4.1 0.66 10.4 4.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5383) HSP70 PF00012.20 CAR25892.1 - 6.6e-182 605.8 0.4 6.6e-182 605.8 0.4 1.7 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CAR25892.1 - 8.3e-10 38.0 0.0 4e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CAR25892.1 - 0.00013 22.3 3.0 0.00052 20.4 0.1 3.1 3 2 0 3 3 3 1 Cell division protein FtsA PilM_2 PF11104.8 CAR25892.1 - 0.00017 20.7 0.0 0.0082 15.2 0.0 2.3 1 1 0 2 2 2 1 Type IV pilus assembly protein PilM; Trans_reg_C PF00486.28 CAR25892.1 - 0.021 14.9 0.0 0.081 13.0 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Endonuc_Holl PF10107.9 CAR25892.1 - 3.6 7.4 7.3 0.5 10.2 0.2 2.5 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Aa_trans PF01490.18 CAR25893.1 - 9.4e-92 307.8 29.0 1.1e-91 307.6 29.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA PF00004.29 CAR25894.1 - 1.5e-40 138.7 0.0 5.3e-40 136.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR25894.1 - 1.4e-06 28.0 0.0 3.8e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CAR25894.1 - 9.5e-05 22.4 0.0 0.00032 20.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAR25894.1 - 0.0001 22.5 0.0 0.00025 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CAR25894.1 - 0.0001 22.6 0.0 0.0019 18.5 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CAR25894.1 - 0.00029 21.3 0.2 0.0026 18.2 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CAR25894.1 - 0.0014 17.9 0.0 0.0025 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CAR25894.1 - 0.0032 17.2 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CAR25894.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAR25894.1 - 0.018 15.2 0.0 0.055 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CAR25894.1 - 0.021 15.4 0.0 0.072 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAR25894.1 - 0.028 13.9 0.0 0.068 12.7 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CAR25894.1 - 0.032 14.0 0.0 0.081 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CAR25894.1 - 0.033 14.6 0.0 0.073 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 CAR25894.1 - 0.051 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CAR25894.1 - 0.055 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CAR25894.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 CAR25894.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CAR25894.1 - 0.17 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 CAR25894.1 - 0.22 11.6 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_pol_Rbc25 PF08292.12 CAR25895.1 - 3.1e-52 176.2 0.4 4e-52 175.9 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CAR25895.1 - 1e-21 77.0 0.0 1.6e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CAR25895.1 - 0.004 17.5 0.0 0.0098 16.2 0.0 1.7 1 1 0 1 1 1 1 S1 RNA binding domain RPA43_OB PF17875.1 CAR25895.1 - 0.043 14.4 0.2 0.074 13.7 0.2 1.4 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I LTV PF04180.14 CAR25896.1 - 1.8e-106 357.1 38.2 2.2e-106 356.9 38.2 1.0 1 0 0 1 1 1 1 Low temperature viability protein DUF3294 PF07957.11 CAR25897.1 - 1.8e-92 308.9 1.1 2.1e-92 308.7 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Pro-rich_19 PF15455.6 CAR25897.1 - 0.04 13.1 0.6 0.053 12.7 0.6 1.1 1 0 0 1 1 1 0 Proline-rich 19 CENP-F_leu_zip PF10473.9 CAR25897.1 - 8.6 6.4 10.4 5.7 7.0 4.5 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PUF PF00806.19 CAR25898.1 - 6.2e-34 113.8 2.7 0.0001 21.8 0.0 8.3 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat TetR_C_8 PF14278.6 CAR25898.1 - 0.26 11.4 2.7 1 9.5 0.4 3.1 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region Cpn60_TCP1 PF00118.24 CAR25899.1 - 2.7e-142 474.9 7.9 3e-142 474.7 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 CAR25899.1 - 0.028 14.7 0.1 0.32 11.4 0.0 2.5 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Vps53_N PF04100.12 CAR25900.1 - 1.1e-93 314.2 9.9 1.9e-93 313.5 9.9 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 CAR25900.1 - 7.9e-88 293.6 4.3 1.5e-87 292.7 4.3 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 53 C-terminus Acetyltransf_15 PF17013.5 CAR25900.1 - 0.0044 16.5 0.1 0.011 15.2 0.1 1.7 1 0 0 1 1 1 1 Putative acetyl-transferase CCDC53 PF10152.9 CAR25900.1 - 0.068 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Peptidase_U57 PF05582.12 CAR25900.1 - 0.15 11.3 0.2 0.26 10.5 0.2 1.3 1 0 0 1 1 1 0 YabG peptidase U57 DUF3724 PF12521.8 CAR25900.1 - 0.24 11.4 1.7 0.36 10.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3724) HORMA PF02301.18 CAR25901.1 - 7.5e-24 84.5 0.2 1.2e-23 83.9 0.2 1.3 1 0 0 1 1 1 1 HORMA domain PPTA PF01239.22 CAR25902.1 - 6.3e-33 111.5 19.5 1.6e-08 33.9 1.3 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Cyclin_N PF00134.23 CAR25903.1 - 1.8e-09 37.4 1.1 3.6e-09 36.4 1.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DEAD PF00270.29 CAR25904.1 - 7.2e-47 159.4 0.0 2.2e-46 157.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR25904.1 - 5.6e-25 87.8 0.0 2e-24 86.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAR25904.1 - 1e-20 73.7 0.0 2.3e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CAR25904.1 - 1.2e-05 25.4 0.0 1.2e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 CAR25904.1 - 0.00096 19.4 1.4 0.0023 18.1 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain CMS1 PF14617.6 CAR25904.1 - 0.016 14.6 0.0 0.016 14.6 0.0 2.9 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit FHA PF00498.26 CAR25905.1 - 1.7e-14 53.9 0.0 3.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CAR25905.1 - 0.0001 22.5 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 CAR25905.1 - 0.0039 17.4 0.0 0.0072 16.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain HSP70 PF00012.20 CAR25906.1 - 3.7e-261 867.6 11.9 4.2e-261 867.4 11.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR25906.1 - 2.6e-18 66.0 2.3 4.3e-17 61.9 0.4 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CAR25906.1 - 0.00026 21.3 3.3 0.64 10.5 0.1 3.7 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 CAR25906.1 - 0.011 15.2 0.3 0.15 11.5 0.3 2.2 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Radial_spoke_3 PF06098.11 CAR25906.1 - 0.012 14.9 1.7 0.024 13.9 1.7 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 Hydantoinase_A PF01968.18 CAR25906.1 - 0.085 12.1 5.7 0.19 10.9 0.1 3.2 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 CAR25906.1 - 0.095 12.4 0.0 0.78 9.4 0.0 2.3 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Secretin_N PF03958.17 CAR25906.1 - 0.12 12.8 1.0 10 6.6 0.0 3.4 4 0 0 4 4 4 0 Bacterial type II/III secretion system short domain DUF790 PF05626.11 CAR25906.1 - 0.41 9.3 3.0 1.6 7.3 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF790) DUF883 PF05957.13 CAR25906.1 - 5.1 7.8 6.5 1.3 9.7 1.5 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) dCMP_cyt_deam_1 PF00383.23 CAR25908.1 - 1.8e-19 69.5 0.0 2.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CAR25908.1 - 2.5e-13 50.0 0.0 3.6e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CAR25908.1 - 0.017 15.3 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 CAR25908.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain NAD1 PF18778.1 CAR25908.1 - 0.076 13.1 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 DUF3525 PF12039.8 CAR25908.1 - 0.14 10.8 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) Bd3614-deam PF14439.6 CAR25908.1 - 0.15 12.2 0.1 0.29 11.2 0.1 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase XOO_2897-deam PF14440.6 CAR25908.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.6 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase PX PF00787.24 CAR25909.1 - 4e-25 88.0 0.3 1.2e-24 86.4 0.3 1.8 1 0 0 1 1 1 1 PX domain DUF4391 PF14335.6 CAR25909.1 - 0.0023 17.7 1.0 0.0023 17.7 1.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4391) Vps5 PF09325.10 CAR25909.1 - 0.015 14.9 1.4 0.015 14.9 1.4 2.4 2 1 0 2 2 2 0 Vps5 C terminal like T3SSipB PF16535.5 CAR25909.1 - 0.083 13.4 0.2 0.083 13.4 0.2 2.3 2 1 0 2 2 2 0 Type III cell invasion protein SipB FlaC_arch PF05377.11 CAR25909.1 - 0.095 13.1 6.4 0.67 10.4 0.1 3.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 CAR25909.1 - 0.31 11.5 2.2 34 5.0 0.5 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3552 PF12072.8 CAR25909.1 - 0.39 10.1 7.9 0.66 9.4 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) bZIP_1 PF00170.21 CAR25909.1 - 0.39 10.9 6.2 13 6.0 0.5 3.7 2 2 1 3 3 3 0 bZIP transcription factor DUF1664 PF07889.12 CAR25909.1 - 0.43 10.6 3.1 3.6 7.7 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 CAR25909.1 - 0.57 9.4 6.8 0.21 10.8 0.4 2.3 1 1 0 2 2 2 0 TMPIT-like protein DASH_Dam1 PF08653.10 CAR25909.1 - 0.67 9.8 4.0 5.3 6.9 0.1 3.9 3 1 1 4 4 4 0 DASH complex subunit Dam1 DUF948 PF06103.11 CAR25909.1 - 0.79 10.0 2.2 2.4 8.5 0.8 2.5 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 CAR25909.1 - 1.6 9.3 14.4 2.6 8.6 0.7 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region Gp-FAR-1 PF05823.12 CAR25909.1 - 1.7 9.0 8.2 0.72 10.2 3.0 2.7 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4407 PF14362.6 CAR25909.1 - 4.2 6.6 5.8 9.8 5.4 0.9 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_TATA_bd PF12325.8 CAR25909.1 - 6.1 7.1 10.2 2.7 8.2 0.6 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding T4_tail_cap PF11091.8 CAR25910.1 - 0.12 11.3 1.1 0.17 10.8 1.1 1.2 1 0 0 1 1 1 0 Tail-tube assembly protein Prefoldin PF02996.17 CAR25910.1 - 0.18 11.8 1.2 0.37 10.7 1.2 1.5 1 0 0 1 1 1 0 Prefoldin subunit Fungal_trans PF04082.18 CAR25911.1 - 1.6e-41 142.1 0.5 4.5e-41 140.7 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR25911.1 - 2e-09 37.4 13.1 3.6e-09 36.6 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NMT1 PF09084.11 CAR25912.1 - 1.2e-78 264.0 0.0 1.4e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 CAR25912.1 - 0.0014 18.3 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 2 NMT1-like family 2Fe-2S_thioredx PF01257.19 CAR25912.1 - 0.017 15.0 1.1 0.028 14.3 1.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin Phosphonate-bd PF12974.7 CAR25912.1 - 0.18 11.4 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF4462 PF14692.6 CAR25912.1 - 4.7 6.8 4.7 2.5 7.7 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) GCD14_N PF14801.6 CAR25914.1 - 0.0028 17.4 0.0 0.019 14.8 0.0 2.3 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit N-term GCD14 PF08704.10 CAR25914.1 - 0.0033 17.2 0.0 0.052 13.2 0.0 2.2 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Ribosomal_L24e PF01246.20 CAR25915.1 - 4.9e-33 113.2 3.7 1.2e-32 111.9 3.7 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e TFIIF_alpha PF05793.12 CAR25915.1 - 0.034 12.7 23.6 0.043 12.4 23.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_3_Rpc31 PF11705.8 CAR25915.1 - 0.1 12.9 17.2 0.15 12.3 17.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4746 PF15928.5 CAR25915.1 - 0.89 8.9 19.8 1.2 8.5 19.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) AAA_23 PF13476.6 CAR25915.1 - 2 8.8 18.6 2.4 8.6 18.6 1.2 1 0 0 1 1 1 0 AAA domain YqfQ PF14181.6 CAR25915.1 - 2.3 8.4 8.2 3.8 7.7 8.2 1.4 1 0 0 1 1 1 0 YqfQ-like protein Mem_trans PF03547.18 CAR25915.1 - 6.2 5.1 7.3 9.1 4.6 7.3 1.2 1 0 0 1 1 1 0 Membrane transport protein GOLD_2 PF13897.6 CAR25915.1 - 7.3 7.1 9.9 86 3.6 0.0 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking PI3K_1B_p101 PF10486.9 CAR25915.1 - 9.4 3.9 13.6 15 3.2 13.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pam16 PF03656.13 CAR25916.1 - 2.9e-06 27.3 0.1 3.7e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 CAR25916.1 - 0.0042 17.2 0.2 0.0069 16.5 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain SMC_Nse1 PF07574.13 CAR25917.1 - 2e-47 161.6 0.0 2.5e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CAR25917.1 - 1.3e-08 35.0 13.4 1.3e-08 35.0 13.4 2.4 3 0 0 3 3 3 1 RING-like domain C1_1 PF00130.22 CAR25917.1 - 1.3 9.0 14.1 0.083 12.8 8.3 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ZapB PF06005.12 CAR25918.1 - 3.7e-05 24.1 8.9 3.7e-05 24.1 8.9 7.9 4 3 2 6 6 6 3 Cell division protein ZapB Spc7 PF08317.11 CAR25918.1 - 0.0017 17.3 17.1 0.0017 17.3 17.1 3.9 1 1 3 4 4 4 1 Spc7 kinetochore protein DASH_Dam1 PF08653.10 CAR25918.1 - 0.075 12.8 0.1 0.075 12.8 0.1 6.3 6 1 1 8 8 8 0 DASH complex subunit Dam1 GAS PF13851.6 CAR25918.1 - 0.92 8.8 78.0 0.29 10.5 16.6 5.1 1 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding SHE3 PF17078.5 CAR25918.1 - 2.8 7.6 76.5 0.1 12.3 25.1 5.6 1 1 4 5 5 5 0 SWI5-dependent HO expression protein 3 Response_reg PF00072.24 CAR25919.1 - 3.4e-19 69.1 0.1 9.9e-13 48.2 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain Ssl1 PF04056.14 CAR25920.1 - 4.1e-84 281.2 0.0 5.5e-84 280.8 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 CAR25920.1 - 1.1e-24 86.4 11.2 1.1e-24 86.4 11.2 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 CAR25920.1 - 1.1e-13 51.8 0.0 1.9e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CAR25920.1 - 0.0012 19.2 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain NPR3 PF03666.13 CAR25920.1 - 5.3 5.7 5.8 8 5.1 5.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-HIT PF04438.16 CAR25920.1 - 5.4 7.0 19.7 0.54 10.2 6.3 3.4 3 0 0 3 3 3 0 HIT zinc finger CDC45 PF02724.14 CAR25920.1 - 9.8 4.3 12.3 13 3.9 12.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUP PF00674.18 CAR25921.1 - 2e-08 34.3 0.2 2e-08 34.3 0.2 2.3 2 1 1 3 3 3 1 DUP family DUP PF00674.18 CAR25922.1 - 2.6e-08 33.9 0.1 2.6e-08 33.9 0.1 2.4 2 0 0 2 2 2 1 DUP family DUP PF00674.18 CAR25923.1 - 9.5e-08 32.1 0.1 9.5e-08 32.1 0.1 2.3 2 1 1 3 3 3 1 DUP family DUP PF00674.18 CAR25924.1 - 2.8e-08 33.8 0.2 2.8e-08 33.8 0.2 2.7 3 0 0 3 3 3 1 DUP family DUP PF00674.18 CAR25925.1 - 5.3e-07 29.7 0.3 5.3e-07 29.7 0.3 2.2 2 1 0 2 2 2 1 DUP family MFS_1 PF07690.16 CAR25927.1 - 7.5e-35 120.5 24.2 1e-34 120.1 24.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5408 PF17402.2 CAR25927.1 - 0.078 12.9 0.1 0.26 11.2 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5408) CMS1 PF14617.6 CAR25928.1 - 5.3e-21 75.1 12.0 2e-20 73.2 12.0 1.8 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit YL1 PF05764.13 CAR25928.1 - 0.0049 17.0 13.0 0.0062 16.7 13.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Merozoite_SPAM PF07133.11 CAR25928.1 - 0.044 13.8 16.8 0.092 12.7 16.8 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 CAR25928.1 - 1.9 6.7 12.0 2.3 6.4 12.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Adaptin_N PF01602.20 CAR25929.1 - 1.6e-87 294.3 13.7 2e-87 294.0 13.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CAR25929.1 - 3.1e-09 37.1 4.5 1.5e-08 34.9 0.1 2.9 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAR25929.1 - 4.6e-05 23.7 2.2 0.24 11.8 0.1 4.2 4 1 1 5 5 5 2 HEAT repeats RTP1_C1 PF10363.9 CAR25929.1 - 0.00042 20.5 2.3 0.0052 16.9 0.2 3.0 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 CAR25929.1 - 0.0053 16.8 0.0 7.7 6.7 0.0 4.0 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat FliS PF02561.14 CAR25929.1 - 0.088 13.1 0.7 4.6 7.5 0.1 2.8 2 0 0 2 2 2 0 Flagellar protein FliS Candida_ALS_N PF11766.8 CAR25930.1 - 2.6e-71 239.8 8.9 2.6e-71 239.8 8.9 3.9 3 1 0 3 3 3 1 Cell-wall agglutinin N-terminal ligand-sugar binding Flocculin PF00624.18 CAR25930.1 - 3.1e-38 129.7 187.3 5.5e-10 39.3 19.9 15.4 12 4 1 13 13 13 6 Flocculin repeat Big_8 PF17961.1 CAR25930.1 - 0.004 17.3 0.1 0.004 17.3 0.1 3.5 3 0 0 3 3 3 1 Bacterial Ig domain CCSAP PF15748.5 CAR25931.1 - 0.0037 17.5 5.3 0.0037 17.5 5.3 2.7 2 1 0 2 2 1 1 Centriole, cilia and spindle-associated SpoIIP PF07454.11 CAR25931.1 - 0.009 15.5 10.0 0.022 14.2 10.0 1.6 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) CDC45 PF02724.14 CAR25931.1 - 0.036 12.4 6.0 0.064 11.5 6.0 1.4 1 0 0 1 1 1 0 CDC45-like protein EIIBC-GUT_N PF03612.14 CAR25931.1 - 0.049 13.4 4.8 0.1 12.3 4.8 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2828 PF11443.8 CAR25931.1 - 0.052 11.6 6.9 0.076 11.1 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) MAS20 PF02064.15 CAR25931.1 - 0.06 13.4 12.9 0.12 12.4 12.9 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor YABBY PF04690.13 CAR25931.1 - 0.25 11.9 6.3 0.91 10.1 6.3 1.9 1 0 0 1 1 1 0 YABBY protein FYDLN_acid PF09538.10 CAR25931.1 - 0.34 11.6 7.5 1.1 10.0 7.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF4820 PF16091.5 CAR25931.1 - 0.38 10.1 10.2 1 8.7 10.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Membralin PF09746.9 CAR25931.1 - 0.56 9.2 4.0 1.1 8.2 4.0 1.5 1 0 0 1 1 1 0 Tumour-associated protein LMBR1 PF04791.16 CAR25931.1 - 0.65 8.8 1.7 0.89 8.4 1.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein CPSF100_C PF13299.6 CAR25931.1 - 0.74 10.0 10.1 2.6 8.2 10.1 1.9 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MecA PF05389.12 CAR25931.1 - 1.2 8.7 11.8 0.044 13.4 5.3 1.8 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF5308 PF17233.2 CAR25931.1 - 1.4 9.1 12.0 0.017 15.3 3.4 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5308) SID-1_RNA_chan PF13965.6 CAR25931.1 - 1.5 7.2 2.9 2.2 6.6 2.9 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAT1 PF09770.9 CAR25931.1 - 2 6.6 22.7 0.02 13.2 13.6 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 CLN3 PF02487.17 CAR25931.1 - 3.3 6.7 12.1 3.2 6.7 9.7 1.9 2 0 0 2 2 2 0 CLN3 protein Borrelia_P83 PF05262.11 CAR25931.1 - 3.7 5.9 13.1 5.6 5.3 13.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1980 PF09323.10 CAR25931.1 - 3.8 7.4 18.1 0.89 9.4 10.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CSG2 PF16965.5 CAR25931.1 - 4.2 6.2 6.7 7.5 5.4 6.7 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator RR_TM4-6 PF06459.12 CAR25931.1 - 4.7 7.0 17.8 0.12 12.2 10.3 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Peptidase_S49_N PF08496.10 CAR25931.1 - 4.9 7.2 16.9 12 6.0 16.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CobT PF06213.12 CAR25931.1 - 5.7 6.2 24.5 13 5.0 24.5 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT eIF-3_zeta PF05091.12 CAR25931.1 - 7.1 5.5 18.2 15 4.4 18.2 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF5523 PF17661.1 CAR25931.1 - 7.6 6.1 21.0 0.15 11.8 14.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5523) Band_3_cyto PF07565.13 CAR25931.1 - 9.7 5.9 13.6 5.3 6.8 10.1 2.1 2 1 0 2 2 2 0 Band 3 cytoplasmic domain Alg6_Alg8 PF03155.15 CAR25932.1 - 2.2e-167 557.9 38.6 2.6e-167 557.7 38.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Vps5 PF09325.10 CAR25933.1 - 2.2e-74 250.0 15.6 2.2e-74 250.0 15.6 1.9 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 CAR25933.1 - 4.9e-23 81.3 0.6 4.9e-23 81.3 0.6 2.7 3 0 0 3 3 3 1 PX domain BAR_3_WASP_bdg PF10456.9 CAR25933.1 - 0.013 14.9 1.4 0.037 13.5 1.4 1.8 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Arfaptin PF06456.13 CAR25933.1 - 0.12 11.9 7.9 2.5 7.6 7.9 2.4 1 1 0 1 1 1 0 Arfaptin-like domain Hydrolase_6 PF13344.6 CAR25933.1 - 2.3 8.4 4.3 4.3 7.5 0.1 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Lactamase_B_4 PF13691.6 CAR25934.1 - 3.7e-27 93.8 0.1 7.6e-27 92.8 0.1 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CAR25934.1 - 1e-10 41.5 0.0 1.5e-05 24.6 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain RabGAP-TBC PF00566.18 CAR25935.1 - 8.1e-52 176.0 2.3 8.1e-52 176.0 2.3 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Macoilin PF09726.9 CAR25935.1 - 0.49 8.9 8.5 0.77 8.3 8.5 1.2 1 0 0 1 1 1 0 Macoilin family Serglycin PF04360.12 CAR25935.1 - 5.4 7.0 14.7 0.72 9.8 7.2 2.6 1 1 1 2 2 2 0 Serglycin THF_DHG_CYH PF00763.23 CAR25936.1 - 2e-25 89.3 0.1 5.6e-25 87.9 0.1 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CAR25936.1 - 1.7e-17 63.2 0.0 2.9e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FTP PF07504.13 CAR25936.1 - 0.0049 16.7 0.4 0.012 15.4 0.4 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif CdiI_N PF18228.1 CAR25936.1 - 0.034 14.0 0.1 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 CdiI N-terminal domain Brix PF04427.18 CAR25937.1 - 3e-37 128.6 0.3 4.4e-37 128.1 0.3 1.2 1 0 0 1 1 1 1 Brix domain NOA36 PF06524.12 CAR25937.1 - 4.5 6.5 9.4 6.9 5.9 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoporin_N PF08801.11 CAR25938.1 - 3e-65 220.7 2.9 4.9e-65 220.0 2.9 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CAR25938.1 - 3.9e-25 88.6 10.3 3.9e-25 88.6 10.3 1.5 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal DASH_Dad2 PF08654.10 CAR25939.1 - 2.6e-32 111.2 1.5 3e-32 111.0 1.5 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 CAR25939.1 - 0.00017 21.3 1.0 0.00029 20.6 1.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 YlbD_coat PF14071.6 CAR25939.1 - 0.093 13.0 3.3 0.46 10.7 0.2 2.0 2 0 0 2 2 2 0 Putative coat protein Histone_HNS PF00816.21 CAR25939.1 - 0.19 12.5 1.9 0.28 12.0 1.9 1.5 1 1 0 1 1 1 0 H-NS histone family Shugoshin_N PF07558.11 CAR25940.1 - 2.5e-16 59.2 1.6 7e-16 57.8 1.6 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 CAR25940.1 - 2.2e-08 33.7 3.9 7.6e-08 32.0 3.9 2.1 1 0 0 1 1 1 1 Shugoshin C terminus CHZ PF09649.10 CAR25940.1 - 0.0086 15.5 0.3 0.025 14.0 0.3 1.8 1 0 0 1 1 1 1 Histone chaperone domain CHZ Thymidylat_synt PF00303.19 CAR25941.1 - 1.8e-116 388.0 0.0 2e-116 387.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Syntaxin-18_N PF10496.9 CAR25942.1 - 4.8e-20 71.6 1.3 4.8e-20 71.6 1.3 2.9 3 1 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 CAR25942.1 - 4e-05 23.5 0.1 4e-05 23.5 0.1 2.3 3 0 0 3 3 3 1 SNARE domain Cluap1 PF10234.9 CAR25942.1 - 0.0028 17.1 23.9 0.003 17.0 5.8 2.2 2 0 0 2 2 2 2 Clusterin-associated protein-1 DUF2120 PF09893.9 CAR25942.1 - 0.17 12.0 7.8 0.16 12.1 4.8 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) L31 PF09784.9 CAR25942.1 - 1.4 9.4 11.2 0.1 13.0 1.4 3.3 2 2 0 2 2 2 0 Mitochondrial ribosomal protein L31 GTP_EFTU PF00009.27 CAR25943.1 - 3.2e-42 144.3 0.0 5.3e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 CAR25943.1 - 8.1e-13 48.5 5.5 1.9e-12 47.3 5.5 1.6 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 CAR25943.1 - 2.9e-06 27.4 0.0 0.0041 17.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 CAR25943.1 - 0.00096 19.4 1.7 0.0012 19.1 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CAR25943.1 - 0.0018 18.6 0.1 0.0049 17.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Roc PF08477.13 CAR25943.1 - 0.017 15.3 0.0 2.1 8.6 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 CAR25943.1 - 0.089 12.7 0.1 0.26 11.2 0.1 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Dabb PF07876.12 CAR25943.1 - 0.82 10.3 3.0 4.7 7.9 0.2 3.1 3 0 0 3 3 3 0 Stress responsive A/B Barrel Domain MRP-L20 PF12824.7 CAR25945.1 - 8e-52 175.7 5.0 9.7e-52 175.4 5.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HA2 PF04408.23 CAR25946.1 - 2.1e-19 69.8 0.0 2.1e-19 69.8 0.0 2.4 3 0 0 3 3 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CAR25946.1 - 4e-15 55.9 0.0 1.1e-14 54.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAR25946.1 - 3.2e-14 53.2 0.1 1.2e-13 51.4 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CAR25946.1 - 1.3e-07 32.0 0.2 4.2e-07 30.3 0.2 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CAR25946.1 - 8.9e-06 25.6 1.4 2.6e-05 24.1 1.4 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CAR25946.1 - 6.7e-05 23.3 0.1 0.00014 22.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR25946.1 - 9e-05 22.3 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CAR25946.1 - 0.0011 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CAR25946.1 - 0.0077 15.7 0.3 0.068 12.6 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 CAR25946.1 - 0.011 15.4 0.2 3.4 7.4 0.0 2.6 1 1 1 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 CAR25946.1 - 0.012 14.7 0.1 0.025 13.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 CAR25946.1 - 0.017 14.8 0.4 0.056 13.1 0.4 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 CAR25946.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Herpes_ori_bp PF02399.15 CAR25946.1 - 0.033 12.2 0.2 0.057 11.5 0.2 1.3 1 0 0 1 1 1 0 Origin of replication binding protein Reprolysin PF01421.19 CAR25946.1 - 0.045 13.6 0.1 0.19 11.6 0.1 2.0 1 1 1 2 2 2 0 Reprolysin (M12B) family zinc metalloprotease ABC_tran PF00005.27 CAR25946.1 - 0.046 14.2 1.0 0.2 12.2 0.0 2.5 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 CAR25946.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Flavi_DEAD PF07652.14 CAR25946.1 - 0.068 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain ResIII PF04851.15 CAR25946.1 - 0.08 12.9 5.3 3.4 7.6 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CAR25946.1 - 0.16 12.0 2.5 1.3 9.1 0.7 2.9 2 1 0 2 2 1 0 AAA domain Peptidase_M48 PF01435.18 CAR25947.1 - 4.9e-30 104.8 0.0 8.7e-30 104.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M48 Kin17_mid PF10357.9 CAR25948.1 - 1.9e-47 160.3 4.9 2.9e-47 159.7 4.9 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 CAR25948.1 - 2.3e-06 27.7 3.9 4.6e-06 26.8 3.9 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAR25948.1 - 3.2e-05 24.1 2.6 6.7e-05 23.1 2.6 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CAR25948.1 - 0.0034 17.7 3.8 0.0036 17.6 0.7 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 CAR25948.1 - 0.0058 16.9 3.6 0.0058 16.9 3.6 1.9 2 0 0 2 2 2 1 A-kinase anchoring protein 95 (AKAP95) DUF640 PF04852.12 CAR25948.1 - 0.011 15.9 0.5 0.25 11.5 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF640) TFIID_NTD2 PF04494.15 CAR25948.1 - 0.083 13.1 1.4 0.22 11.7 1.3 1.8 1 1 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain zf-C2H2_4 PF13894.6 CAR25948.1 - 0.18 12.8 1.1 0.46 11.5 1.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger SNARE_assoc PF09335.11 CAR25949.1 - 8.2e-14 52.1 6.1 8.2e-14 52.1 6.1 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein TctB PF07331.11 CAR25949.1 - 0.00067 19.9 8.7 0.00067 19.9 8.7 2.1 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family DUF3188 PF11384.8 CAR25949.1 - 0.12 12.1 1.8 0.23 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) TssN PF17555.2 CAR25949.1 - 0.21 11.0 7.2 0.36 10.2 2.9 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN DUF4234 PF14018.6 CAR25949.1 - 8.3 6.6 6.8 1.6 8.9 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) adh_short_C2 PF13561.6 CAR25950.1 - 8.8e-62 208.7 0.0 1.1e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR25950.1 - 2e-41 141.6 0.1 2.4e-41 141.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR25950.1 - 1.7e-08 34.6 0.3 5.7e-08 32.9 0.3 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CAR25950.1 - 0.021 14.3 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Nre_N PF04894.12 CAR25950.1 - 0.066 13.0 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal Nre, N-terminal 3HCDH_N PF02737.18 CAR25950.1 - 0.067 13.1 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Haem_degrading PF03928.14 CAR25951.1 - 7.4e-10 38.9 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Haem-degrading Pyridox_oxase_2 PF12766.7 CAR25952.1 - 3.2e-30 104.7 0.0 6.4e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aminotran_3 PF00202.21 CAR25953.1 - 1.4e-102 343.4 0.0 1.9e-102 343.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III SipA_VBS PF17985.1 CAR25953.1 - 0.049 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 SipA vinculin binding site fn3_2 PF16893.5 CAR25954.1 - 1.9e-40 136.9 0.3 3.7e-40 136.0 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 CAR25954.1 - 7.3e-24 83.5 0.2 1.2e-23 82.8 0.2 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 CAR25954.1 - 1.3e-08 35.0 0.1 5.2e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.21 CAR25954.1 - 0.0015 18.9 0.1 0.0049 17.2 0.1 1.9 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.8 CAR25954.1 - 0.0056 16.9 0.0 0.0056 16.9 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3006) PTCB-BRCT PF12738.7 CAR25954.1 - 0.0087 16.0 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CAR25954.1 - 0.037 14.4 0.0 0.15 12.4 0.0 2.1 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Mur_ligase PF01225.25 CAR25954.1 - 0.081 13.3 0.7 0.67 10.3 0.0 2.7 2 0 0 2 2 2 0 Mur ligase family, catalytic domain ATP-synt_F PF01990.17 CAR25955.1 - 4.1e-30 104.0 0.1 4.7e-30 103.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Transcrip_reg PF01709.20 CAR25956.1 - 1.3e-73 247.4 0.2 1.4e-73 247.2 0.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF4258 PF14076.6 CAR25956.1 - 0.084 13.3 0.0 2.9 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) DUF3656 PF12392.8 CAR25956.1 - 0.11 13.2 0.4 0.55 10.9 0.2 2.1 2 0 0 2 2 2 0 Collagenase RRM_1 PF00076.22 CAR25956.1 - 0.13 12.1 0.1 0.62 9.9 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mid2 PF04478.12 CAR25957.1 - 7.2e-58 194.7 0.5 7.2e-58 194.7 0.5 3.3 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 CAR25957.1 - 0.0095 15.3 0.6 0.089 12.2 0.6 2.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Thg1 PF04446.12 CAR25958.1 - 4.2e-50 169.0 1.1 6.3e-50 168.4 1.1 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 CAR25958.1 - 4.3e-39 133.4 0.2 6.8e-39 132.8 0.2 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Xpo1 PF08389.12 CAR25958.1 - 0.055 13.5 0.6 6.3 6.9 0.1 2.2 2 0 0 2 2 2 0 Exportin 1-like protein SecY PF00344.20 CAR25959.1 - 0.044 13.0 5.4 0.17 11.1 0.2 2.2 1 1 1 2 2 2 0 SecY translocase LrgB PF04172.16 CAR25959.1 - 0.076 12.5 0.9 0.11 12.0 0.9 1.4 1 0 0 1 1 1 0 LrgB-like family TatC PF00902.18 CAR25959.1 - 0.083 12.7 12.3 0.015 15.1 8.7 1.6 2 1 0 2 2 2 0 Sec-independent protein translocase protein (TatC) Ribosomal_S25 PF03297.15 CAR25960.1 - 1e-40 138.0 6.0 1.1e-40 137.8 6.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 CAR25960.1 - 0.0035 17.1 0.1 0.0054 16.5 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.11 CAR25960.1 - 0.016 14.7 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 CodY helix-turn-helix domain EAP30 PF04157.16 CAR25960.1 - 0.054 12.8 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family GntR PF00392.21 CAR25960.1 - 0.071 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Ran_BP1 PF00638.18 CAR25961.1 - 1.8e-34 118.6 0.3 4.9e-34 117.2 0.3 1.8 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 CAR25961.1 - 3.3e-15 56.5 3.5 3.3e-15 56.5 3.5 4.6 3 2 0 3 3 3 1 NUP50 (Nucleoporin 50 kDa) MA3 PF02847.17 CAR25962.1 - 4.1e-29 100.8 0.3 1.6e-28 99.0 0.3 2.1 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 CAR25962.1 - 2.1e-23 83.1 3.1 2.1e-23 83.1 3.1 2.3 2 0 0 2 2 2 1 MIF4G domain LAP1C PF05609.12 CAR25962.1 - 1.2 8.1 30.3 0.0085 15.2 7.0 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) AAA PF00004.29 CAR25963.1 - 2.1e-35 122.0 0.0 4.3e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR25963.1 - 1.1e-09 37.9 0.1 2.9e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 CAR25963.1 - 1.4e-06 28.4 0.0 5.3e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAR25963.1 - 3.3e-06 27.6 0.2 2.1e-05 24.9 0.1 2.4 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 CAR25963.1 - 6.8e-06 25.9 0.0 3.7e-05 23.5 0.0 2.3 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CAR25963.1 - 9.1e-06 26.0 0.4 0.0013 19.0 0.1 3.3 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.14 CAR25963.1 - 2.5e-05 24.3 0.0 0.00016 21.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAR25963.1 - 4e-05 23.8 0.0 0.00016 21.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TniB PF05621.11 CAR25963.1 - 0.00016 21.1 0.1 0.24 10.8 0.0 2.5 2 1 0 3 3 2 2 Bacterial TniB protein Sigma54_activ_2 PF14532.6 CAR25963.1 - 0.00027 21.0 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 CAR25963.1 - 0.00028 21.1 0.0 0.0005 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CAR25963.1 - 0.00035 20.3 0.0 0.00088 19.1 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 CAR25963.1 - 0.00063 20.3 0.0 0.0018 18.8 0.0 1.9 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CAR25963.1 - 0.0013 18.2 0.1 0.0028 17.1 0.1 1.6 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CAR25963.1 - 0.0019 18.1 0.1 0.0051 16.8 0.0 1.7 2 0 0 2 2 1 1 NACHT domain RNA_helicase PF00910.22 CAR25963.1 - 0.002 18.5 0.0 0.0049 17.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.13 CAR25963.1 - 0.006 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Rad17 PF03215.15 CAR25963.1 - 0.0068 16.3 0.1 0.032 14.2 0.0 1.9 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 CAR25963.1 - 0.0069 16.0 0.1 0.077 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 CAR25963.1 - 0.0078 15.9 0.0 0.035 13.8 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain Viral_helicase1 PF01443.18 CAR25963.1 - 0.0096 15.7 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 CAR25963.1 - 0.012 16.2 0.0 0.027 15.0 0.0 1.8 2 1 0 2 2 1 0 ABC transporter TIP49 PF06068.13 CAR25963.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Zeta_toxin PF06414.12 CAR25963.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.11 CAR25963.1 - 0.013 15.3 0.0 0.066 13.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CAR25963.1 - 0.015 15.5 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 CAR25963.1 - 0.02 15.2 0.0 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_7 PF12775.7 CAR25963.1 - 0.023 14.2 0.0 0.08 12.5 0.0 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 CAR25963.1 - 0.03 14.2 0.0 0.063 13.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein TsaE PF02367.17 CAR25963.1 - 0.043 13.8 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CAR25963.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CAR25963.1 - 0.068 13.6 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CAR25963.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain CPT PF07931.12 CAR25963.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.6 CAR25963.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.11 CAR25963.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA ligase kinase domain Parvo_NS1 PF01057.17 CAR25963.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PELOTA_1 PF15608.6 CAR25963.1 - 0.16 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 PELOTA RNA binding domain Oxidored_nitro PF00148.19 CAR25963.1 - 0.17 10.6 0.0 13 4.3 0.0 2.1 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase SMC_N PF02463.19 CAR25963.1 - 0.2 11.1 0.2 16 4.8 0.0 2.2 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain Evr1_Alr PF04777.13 CAR25964.1 - 1.7e-28 99.0 4.0 1.7e-28 99.0 4.0 1.4 2 0 0 2 2 2 1 Erv1 / Alr family LolA_2 PF16584.5 CAR25964.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA WH2 PF02205.20 CAR25965.1 - 3.2e-14 52.2 0.5 9e-10 38.1 0.0 2.9 2 0 0 2 2 2 2 WH2 motif DUF3445 PF11927.8 CAR25966.1 - 9e-58 195.6 0.0 1.4e-57 194.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Alba PF01918.21 CAR25967.1 - 4.3e-05 23.3 0.2 0.00015 21.5 0.2 1.8 1 1 0 1 1 1 1 Alba DUF5039 PF16442.5 CAR25967.1 - 0.0082 15.7 0.2 0.01 15.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5039) Ribosomal_L10 PF00466.20 CAR25968.1 - 6.5e-25 87.2 0.1 9.8e-25 86.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CAR25968.1 - 1.4e-21 76.3 0.0 2.3e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CAR25968.1 - 1.9e-18 66.8 5.0 3.4e-18 66.0 1.6 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein HMG_box_5 PF14887.6 CAR25969.1 - 0.12 12.4 0.0 0.42 10.6 0.0 2.0 1 0 0 1 1 1 0 HMG (high mobility group) box 5 Abhydrolase_1 PF00561.20 CAR25970.1 - 3.7e-24 85.8 0.0 7.5e-24 84.7 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR25970.1 - 2.9e-15 57.5 0.0 4e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR25970.1 - 2.7e-11 43.2 0.0 5.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CAR25970.1 - 2e-05 24.5 0.0 0.00041 20.2 0.0 2.2 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.16 CAR25970.1 - 0.0026 17.6 0.0 0.09 12.6 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF676 PF05057.14 CAR25970.1 - 0.015 14.8 0.0 0.055 13.0 0.0 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Esterase PF00756.20 CAR25970.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 CAR25970.1 - 0.035 14.2 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.7 CAR25970.1 - 0.059 12.3 0.0 0.096 11.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 CAR25970.1 - 0.088 12.3 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Nucleoporin_FG PF13634.6 CAR25970.1 - 0.16 12.8 0.8 1.3 9.9 0.2 2.0 2 0 0 2 2 2 0 Nucleoporin FG repeat region Glucan_synthase PF02364.15 CAR25971.1 - 0 1351.8 0.0 0 1351.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CAR25971.1 - 5.7e-43 146.3 0.1 1.5e-42 145.0 0.1 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.14 CAR25972.1 - 4.9e-138 459.7 2.5 6.9e-138 459.2 2.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CAR25972.1 - 5e-16 59.1 0.1 1.3e-15 57.8 0.1 1.7 1 0 0 1 1 1 1 X8 domain TIM21 PF08294.11 CAR25973.1 - 4.4e-51 172.6 0.0 5.4e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 TIM21 DUF411 PF04214.13 CAR25973.1 - 0.043 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF Ribosomal_L26 PF16906.5 CAR25974.1 - 2.3e-35 120.9 3.6 4.2e-35 120.1 3.6 1.4 1 1 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CAR25974.1 - 2.4e-05 24.1 1.0 6.6e-05 22.7 1.0 1.7 1 0 0 1 1 1 1 KOW motif 6PF2K PF01591.18 CAR25975.1 - 1.6e-62 210.7 1.2 2.2e-62 210.3 1.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CAR25975.1 - 1.5e-19 70.4 0.0 3.5e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CAR25975.1 - 0.0014 18.8 0.1 0.0029 17.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain PAP2 PF01569.21 CAR25976.1 - 3.3e-18 65.8 1.1 5.5e-18 65.0 1.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 CAR25976.1 - 0.068 13.3 0.1 0.36 11.0 0.0 2.0 1 1 1 2 2 2 0 Divergent PAP2 family HEAT PF02985.22 CAR25977.1 - 4.6e-14 51.3 17.8 0.0079 16.4 0.1 10.3 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.6 CAR25977.1 - 1.2e-12 48.0 7.2 1.2e-05 25.7 0.0 8.4 7 2 2 9 9 9 2 HEAT-like repeat IBN_N PF03810.19 CAR25977.1 - 8e-09 35.3 4.0 1.1e-07 31.7 1.1 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.7 CAR25977.1 - 6.2e-07 29.6 1.0 0.0057 16.7 0.0 4.5 4 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAR25977.1 - 4.3e-06 27.0 6.5 0.039 14.4 0.0 6.5 3 2 6 9 9 9 1 HEAT repeats DUF3347 PF11827.8 CAR25977.1 - 0.00033 20.9 0.6 0.011 16.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3347) Arm PF00514.23 CAR25977.1 - 0.00033 20.6 4.0 2.2 8.5 0.0 5.8 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 CAR25977.1 - 0.00062 19.4 2.8 2.2 7.8 0.0 4.8 4 2 2 6 6 6 2 CLASP N terminal Sec7_N PF12783.7 CAR25977.1 - 0.0078 16.1 0.2 0.15 11.9 0.1 3.1 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal RIX1 PF08167.12 CAR25977.1 - 0.022 14.5 0.5 0.82 9.4 0.1 3.4 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis CTD_bind PF04818.13 CAR25977.1 - 0.043 14.7 1.1 12 6.8 0.0 4.5 5 1 0 5 5 3 0 RNA polymerase II-binding domain. Telomere_reg-2 PF10193.9 CAR25977.1 - 0.11 12.9 5.5 0.29 11.6 0.2 4.0 3 1 0 3 3 3 0 Telomere length regulation protein ACBP PF00887.19 CAR25978.1 - 1.5e-27 95.6 2.9 1.7e-27 95.4 2.9 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 CAR25978.1 - 0.01 16.3 0.2 3.2 8.2 0.0 2.0 1 1 1 2 2 2 0 FERM central domain ORMDL PF04061.14 CAR25979.1 - 4.2e-57 191.8 5.1 5e-57 191.5 5.1 1.1 1 0 0 1 1 1 1 ORMDL family DUF4271 PF14093.6 CAR25979.1 - 0.0052 16.7 0.5 0.0059 16.5 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) CN_hydrolase PF00795.22 CAR25980.1 - 1.3e-61 208.2 0.0 1.5e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DAO PF01266.24 CAR25981.1 - 2.8e-31 109.4 0.0 3.2e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAR25981.1 - 0.021 15.0 1.8 0.037 14.3 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pkinase PF00069.25 CAR25982.1 - 2.2e-67 227.2 0.0 2.7e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR25982.1 - 1.2e-32 113.2 0.0 2e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR25982.1 - 7.6e-05 22.2 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAR25982.1 - 0.0019 17.6 0.1 0.0043 16.4 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAR25982.1 - 0.0031 16.5 0.1 0.0049 15.9 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CAR25982.1 - 0.027 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CAR25982.1 - 0.054 13.1 0.1 0.11 12.1 0.1 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CAR25982.1 - 0.099 12.2 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 RIO1 family LRR_4 PF12799.7 CAR25983.1 - 0.0015 18.9 19.4 0.024 15.1 2.6 5.6 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) UNC119_bdg PF15435.6 CAR25983.1 - 0.017 14.7 0.2 0.046 13.3 0.0 1.8 2 0 0 2 2 2 0 UNC119-binding protein C5orf30 homologue LRR_6 PF13516.6 CAR25983.1 - 0.068 13.3 10.9 11 6.3 0.1 5.1 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.6 CAR25983.1 - 1.2 9.0 13.6 0.33 10.7 1.4 4.6 5 0 0 5 5 5 0 Leucine rich repeat DUF1870 PF08965.10 CAR25983.1 - 1.5 8.9 3.7 0.75 9.8 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1870) LRR_1 PF00560.33 CAR25983.1 - 1.6 9.6 10.4 3e+02 2.7 0.0 6.7 6 0 0 6 6 6 0 Leucine Rich Repeat DNA_pol_phi PF04931.13 CAR25984.1 - 0.91 7.5 12.4 1.5 6.9 12.4 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CAR25984.1 - 3 6.0 7.3 6 5.0 7.3 1.4 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 CAR25984.1 - 3.6 6.8 16.6 8.7 5.6 16.6 1.6 1 0 0 1 1 1 0 NOA36 protein DUF2439 PF10382.9 CAR25985.1 - 1.3e-09 38.3 0.1 1.9e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) TAL_FSA PF00923.19 CAR25986.1 - 6.1e-95 317.9 0.1 7e-95 317.7 0.1 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase zf-C2H2 PF00096.26 CAR25987.1 - 1.3e-06 28.6 15.1 0.0027 18.1 1.7 3.6 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR25987.1 - 0.00014 22.4 16.5 0.024 15.4 0.4 4.0 3 1 0 3 3 3 2 C2H2-type zinc finger WRKY PF03106.15 CAR25987.1 - 0.036 14.3 0.4 0.13 12.5 0.4 1.9 1 0 0 1 1 1 0 WRKY DNA -binding domain PyrI_C PF02748.15 CAR25987.1 - 0.038 13.9 0.8 4.2 7.3 0.1 2.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.7 CAR25987.1 - 0.039 14.3 5.1 1.1 9.6 0.1 2.5 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 CAR25987.1 - 0.061 13.5 3.4 1.3 9.1 0.7 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger DUF4422 PF14393.6 CAR25987.1 - 0.069 13.0 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) zf-C2H2_11 PF16622.5 CAR25987.1 - 0.23 11.3 7.3 2.6 7.9 0.1 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF629 PF04780.12 CAR25987.1 - 0.29 9.6 2.4 4.2 5.8 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_jaz PF12171.8 CAR25987.1 - 5.6 7.4 14.2 1.4 9.3 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding AhpC-TSA PF00578.21 CAR25988.1 - 2.5e-27 95.2 0.0 3.3e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAR25988.1 - 2.3e-10 40.4 0.0 3.1e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 CAR25988.1 - 1.9e-06 27.6 0.1 3.2e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin WD40 PF00400.32 CAR25989.1 - 2e-46 155.0 19.4 8.2e-10 39.1 0.2 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CAR25989.1 - 1.5e-40 138.4 2.5 2.5e-40 137.7 2.5 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CAR25989.1 - 1.4e-12 47.7 0.0 0.16 12.3 0.0 6.1 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CAR25989.1 - 9.1e-07 28.6 0.1 2.2e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 CAR25989.1 - 0.0003 19.6 3.3 0.67 8.5 0.0 3.9 4 1 2 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CAR25989.1 - 0.00031 19.8 0.0 0.68 8.8 0.0 3.5 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CAR25989.1 - 0.00059 19.3 0.0 3 7.1 0.0 3.4 3 0 0 3 3 3 2 WD40-like domain GPI2 PF06432.11 CAR25990.1 - 2.8e-50 171.4 25.3 3.5e-50 171.0 25.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF5315 PF17242.2 CAR25991.1 - 8.1e-25 86.5 0.1 1.5e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) PGI PF00342.19 CAR25992.1 - 3.4e-243 807.6 5.7 4e-243 807.3 5.7 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase WD40 PF00400.32 CAR25993.1 - 3.2e-18 65.7 6.2 0.00033 21.4 1.2 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CAR25993.1 - 7.7e-17 61.3 0.9 2.4e-16 59.7 0.9 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 CAR25993.1 - 2e-10 40.8 0.0 0.0013 19.0 0.0 4.0 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR25993.1 - 0.00037 20.4 0.0 0.17 11.7 0.0 2.9 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A SdiA-regulated PF06977.11 CAR25993.1 - 0.065 12.5 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 SdiA-regulated Mt_ATP-synt_B PF05405.14 CAR25994.1 - 8.1e-56 188.1 10.0 9.8e-56 187.9 10.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) NpwBP PF12622.7 CAR25995.1 - 6e-12 46.1 1.0 8.4e-12 45.7 1.0 1.4 1 1 0 1 1 1 1 mRNA biogenesis factor Med8 PF10232.9 CAR25996.1 - 6.7e-16 58.6 1.2 9e-16 58.2 1.2 1.3 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Mito_carr PF00153.27 CAR25997.1 - 3.8e-77 254.3 3.4 3.5e-27 94.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 CAR25997.1 - 0.0044 17.2 0.0 1.3 9.3 0.0 3.1 3 0 0 3 3 3 1 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Ribosomal_L21e PF01157.18 CAR25998.1 - 1.1e-39 134.4 3.4 1.1e-39 134.4 3.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e SIMPL PF04402.14 CAR25998.1 - 0.022 15.2 0.0 0.026 15.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF541) S4 PF01479.25 CAR25999.1 - 7.6e-11 41.6 0.4 7.6e-11 41.6 0.4 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 CAR25999.1 - 0.00033 21.5 0.4 0.0006 20.7 0.3 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain HMGL-like PF00682.19 CAR26000.1 - 8e-84 281.3 0.0 1e-83 280.9 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.20 CAR26000.1 - 0.055 12.3 0.0 5.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Tryptophan synthase alpha chain DUF3535 PF12054.8 CAR26001.1 - 5.7e-110 368.5 0.1 4.9e-109 365.5 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 CAR26001.1 - 2e-67 227.4 0.0 5e-67 226.1 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR26001.1 - 2.3e-19 69.8 0.0 3.5e-18 66.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 CAR26001.1 - 1.1e-08 34.6 7.5 2.9 8.4 0.0 8.5 9 0 0 9 9 9 3 HEAT repeat ResIII PF04851.15 CAR26001.1 - 4.7e-06 26.7 0.0 3.4e-05 23.9 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Vac14_Fab1_bd PF12755.7 CAR26001.1 - 0.00013 22.5 0.0 1.8 9.2 0.0 4.7 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 CAR26001.1 - 0.0079 16.5 0.0 11 6.4 0.0 4.5 4 1 1 5 5 5 1 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 CAR26001.1 - 0.012 16.1 4.3 31 5.2 0.0 6.6 7 0 0 7 7 7 0 HEAT-like repeat ERCC3_RAD25_C PF16203.5 CAR26001.1 - 0.016 14.5 0.0 0.035 13.3 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase GUN4_N PF16416.5 CAR26001.1 - 0.14 12.1 0.3 5.2 7.1 0.0 2.9 2 0 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal cwf18 PF08315.12 CAR26002.1 - 1.8e-07 31.9 13.1 0.00073 20.2 1.3 2.1 1 1 1 2 2 2 2 cwf18 pre-mRNA splicing factor KicB PF03882.14 CAR26002.1 - 0.077 13.2 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 MukF winged-helix domain UPF0016 PF01169.19 CAR26003.1 - 7.2e-41 138.4 22.7 6.3e-21 74.5 8.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Cation_ATPase_C PF00689.21 CAR26003.1 - 9.7 5.9 10.6 44 3.7 10.6 2.0 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus AAA PF00004.29 CAR26004.1 - 6.4e-32 110.8 0.0 1.2e-31 109.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CAR26004.1 - 1e-05 25.8 0.0 2.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAR26004.1 - 3.4e-05 24.3 0.0 0.00024 21.5 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CAR26004.1 - 0.00014 21.9 0.1 0.083 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CAR26004.1 - 0.00017 21.9 0.0 0.0037 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR26004.1 - 0.00021 21.8 0.0 0.00049 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAR26004.1 - 0.00023 21.1 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CAR26004.1 - 0.00081 19.4 0.1 0.0043 17.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 CAR26004.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CAR26004.1 - 0.0031 17.2 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CAR26004.1 - 0.0034 17.8 0.0 0.011 16.1 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CAR26004.1 - 0.0042 17.1 0.1 0.015 15.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CAR26004.1 - 0.0068 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 CAR26004.1 - 0.0071 16.5 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CAR26004.1 - 0.013 15.5 0.0 0.048 13.7 0.0 1.9 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.14 CAR26004.1 - 0.013 14.7 0.1 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase DUF2075 PF09848.9 CAR26004.1 - 0.016 14.5 0.0 0.031 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CAR26004.1 - 0.016 15.1 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.6 CAR26004.1 - 0.018 15.5 0.1 0.059 13.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CAR26004.1 - 0.021 14.6 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain T2SSE PF00437.20 CAR26004.1 - 0.021 13.9 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 CAR26004.1 - 0.027 15.0 0.0 0.073 13.6 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Cytidylate_kin PF02224.18 CAR26004.1 - 0.037 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase IstB_IS21 PF01695.17 CAR26004.1 - 0.037 13.8 0.1 0.18 11.6 0.0 2.1 3 0 0 3 3 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 CAR26004.1 - 0.038 13.9 0.1 0.074 12.9 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_3 PF07726.11 CAR26004.1 - 0.046 13.6 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CAR26004.1 - 0.054 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CAR26004.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 CAR26004.1 - 0.13 12.8 0.9 0.2 12.1 0.2 1.9 2 1 0 2 2 1 0 AAA domain ATPase PF06745.13 CAR26004.1 - 0.13 11.6 0.1 0.56 9.5 0.0 1.8 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 CAR26004.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein RhoGEF PF00621.20 CAR26004.1 - 0.15 12.3 0.5 0.74 10.0 0.1 2.1 2 0 0 2 2 2 0 RhoGEF domain tRNA_int_end_N2 PF12928.7 CAR26005.1 - 1.2e-16 60.7 0.0 2.3e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term BRO1 PF03097.18 CAR26006.1 - 3.8e-94 315.7 7.8 3.8e-94 315.7 7.8 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CAR26006.1 - 1.3e-25 90.3 4.9 1.3e-25 90.3 4.9 2.3 2 1 1 3 3 3 1 ALIX V-shaped domain binding to HIV MBD_C PF14048.6 CAR26006.1 - 0.12 13.1 0.0 0.4 11.4 0.0 1.9 1 0 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 DUF627 PF04781.12 CAR26006.1 - 0.58 10.2 3.1 0.76 9.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF627) MBA1 PF07961.11 CAR26007.1 - 1.4e-101 338.5 1.2 1.7e-101 338.2 1.2 1.0 1 0 0 1 1 1 1 MBA1-like protein Glyco_transf_20 PF00982.21 CAR26007.1 - 0.016 13.9 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 20 Sec16_C PF12931.7 CAR26008.1 - 4.5e-75 253.1 0.0 8.3e-75 252.2 0.0 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CAR26008.1 - 4.5e-07 30.5 0.0 4.5e-07 30.5 0.0 3.6 3 0 0 3 3 3 1 Vesicle coat trafficking protein Sec16 mid-region Trypan_PARP PF05887.11 CAR26008.1 - 0.00031 20.7 17.0 0.00031 20.7 17.0 8.2 4 2 2 7 7 7 1 Procyclic acidic repetitive protein (PARP) Radical_SAM_C PF16199.5 CAR26009.1 - 2.1e-32 111.0 0.0 4.1e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CAR26009.1 - 2e-18 67.3 0.7 5.8e-18 65.8 0.1 2.0 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CAR26009.1 - 5.1e-11 42.8 0.1 8.7e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR26009.1 - 4.8e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR26009.1 - 0.044 14.2 0.0 0.092 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ceramidase PF05875.12 CAR26010.1 - 3.4e-91 305.3 16.5 3.9e-91 305.1 16.5 1.0 1 0 0 1 1 1 1 Ceramidase Phage_holin_2_2 PF10746.9 CAR26010.1 - 0.0053 16.4 0.1 0.017 14.8 0.1 1.9 1 0 0 1 1 1 1 Phage holin T7 family, holin superfamily II SRF-TF PF00319.18 CAR26011.1 - 4.4e-21 74.1 0.1 7.1e-21 73.4 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Phage_tail_3 PF08813.11 CAR26011.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Phage tail tube protein, TTP TFIIA PF03153.13 CAR26011.1 - 1.4 8.9 18.2 2.1 8.3 18.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HSP20 PF00011.21 CAR26012.1 - 1.5e-18 66.8 0.0 2e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CAR26012.1 - 0.00026 20.5 0.0 0.00042 19.8 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA FAD_binding_7 PF03441.14 CAR26013.1 - 7e-67 224.8 0.7 7e-67 224.8 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CAR26013.1 - 2.7e-26 92.5 0.3 1.7e-25 89.9 0.3 2.1 1 1 0 1 1 1 1 DNA photolyase SnoaL_4 PF13577.6 CAR26014.1 - 1e-25 90.3 0.0 1.2e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Epimerase PF01370.21 CAR26015.1 - 9.4e-22 77.6 0.0 1.7e-21 76.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR26015.1 - 2.3e-17 62.9 0.0 3.5e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CAR26015.1 - 5.1e-12 45.8 0.0 2.7e-11 43.5 0.0 2.0 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CAR26015.1 - 6e-12 45.3 0.0 1.1e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 CAR26015.1 - 2e-07 30.5 0.1 3.1e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CAR26015.1 - 3.2e-06 27.1 0.0 4.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CAR26015.1 - 0.00011 21.9 0.0 0.055 13.0 0.0 3.0 3 0 0 3 3 3 1 NmrA-like family KR PF08659.10 CAR26015.1 - 0.00046 20.1 0.0 0.00091 19.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 CAR26015.1 - 0.0012 19.1 0.6 0.0039 17.4 0.0 2.1 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 CAR26015.1 - 0.0017 17.8 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 CAR26015.1 - 0.006 15.7 0.0 0.0087 15.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain DUF2788 PF10981.8 CAR26015.1 - 0.12 12.4 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2788) Zn_clus PF00172.18 CAR26016.1 - 6e-08 32.7 10.9 1.4e-07 31.5 10.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CAR26017.1 - 4.7e-32 111.3 29.0 4.7e-32 111.3 29.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR26017.1 - 5.7e-05 21.7 2.4 8.4e-05 21.2 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GST_N PF02798.20 CAR26018.1 - 2.3e-17 63.1 0.1 9.1e-17 61.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CAR26018.1 - 9.2e-11 41.8 0.0 2.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CAR26018.1 - 5.9e-09 36.2 0.0 7.7e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CAR26018.1 - 9.6e-07 29.0 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CAR26018.1 - 1.4e-06 28.4 0.3 5.1e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAR26018.1 - 0.002 18.1 0.0 0.0046 17.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Flo11 PF10182.9 CAR26019.1 - 1.1e-69 233.3 2.7 1.1e-69 233.3 2.7 1.8 2 0 0 2 2 2 1 Flo11 domain MFS_1 PF07690.16 CAR26020.1 - 5.8e-34 117.6 26.1 7.2e-34 117.3 26.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Spindle_Spc25 PF08234.12 CAR26021.1 - 0.032 14.4 0.5 0.041 14.1 0.5 1.2 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 HATPase_c_2 PF13581.6 CAR26021.1 - 0.2 11.6 1.0 0.25 11.3 1.0 1.1 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Astro_capsid_p PF12226.8 CAR26021.1 - 0.41 9.8 6.4 0.4 9.8 6.4 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TRAP_alpha PF03896.16 CAR26021.1 - 1 8.5 4.9 1.2 8.3 4.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 CAR26021.1 - 8 4.6 9.5 7.9 4.6 9.5 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 CAR26021.1 - 9.4 5.4 10.8 11 5.3 10.8 1.1 1 0 0 1 1 1 0 NOA36 protein DUP PF00674.18 CAR26022.1 - 3.5e-17 62.4 0.2 7e-17 61.4 0.2 1.6 1 1 0 1 1 1 1 DUP family DUP PF00674.18 CAR26024.1 - 3e-07 30.5 0.9 3e-07 30.5 0.9 2.3 2 0 0 2 2 2 1 DUP family DUF4532 PF15046.6 CAR26024.1 - 0.16 11.1 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4532) DUP PF00674.18 CAR26026.1 - 2.1e-08 34.2 0.1 2.1e-08 34.2 0.1 3.3 2 1 1 3 3 3 1 DUP family Vesiculo_matrix PF06326.12 CAR26026.1 - 0.057 13.2 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Vesiculovirus matrix protein DUP PF00674.18 CAR26027.1 - 2.4e-32 111.2 6.5 7.8e-17 61.3 0.3 2.5 2 0 0 2 2 2 2 DUP family DUF1360 PF07098.11 CAR26027.1 - 0.0098 15.8 0.6 0.0098 15.8 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1360) AAA_26 PF13500.6 CAR26028.1 - 3.3e-38 131.5 0.0 4.2e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain Aminotran_3 PF00202.21 CAR26029.1 - 5.8e-102 341.4 0.0 1.1e-101 340.5 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CAR26029.1 - 0.00026 20.4 0.0 0.00047 19.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DUP PF00674.18 CAR26030.1 - 3.3e-09 36.8 0.1 3.3e-09 36.8 0.1 2.7 2 1 1 3 3 3 1 DUP family Comm PF15957.5 CAR26030.1 - 1.2 9.5 3.8 18 5.7 0.0 2.4 2 0 0 2 2 2 0 Commissureless DUP PF00674.18 CAR26032.1 - 5.9e-41 138.8 4.2 6.4e-22 77.6 1.7 2.4 2 0 0 2 2 2 2 DUP family Sortilin-Vps10 PF15902.5 CAR26033.1 - 3.9e-53 180.8 4.7 2.7e-29 102.3 0.2 2.9 2 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CAR26033.1 - 4.6e-14 53.1 0.9 8.8e-14 52.2 0.9 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CAR26033.1 - 8.5e-10 37.2 14.5 0.77 10.0 0.0 7.6 6 0 0 6 6 6 4 BNR/Asp-box repeat PSII_BNR PF14870.6 CAR26033.1 - 0.00053 19.4 0.4 0.099 11.9 0.1 3.5 3 1 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.16 CAR26033.1 - 0.0014 18.7 0.5 25 4.9 0.0 4.6 6 0 0 6 6 6 0 Mo-co oxidoreductase dimerisation domain CHB_HEX_C PF03174.13 CAR26033.1 - 0.044 13.7 0.5 4.4 7.4 0.0 3.8 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain ApoC-I PF04691.12 CAR26033.1 - 0.082 12.8 0.6 0.55 10.2 0.0 2.4 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Nitr_red_alph_N PF14710.6 CAR26033.1 - 0.15 12.6 3.1 0.36 11.3 0.1 3.2 3 0 0 3 3 3 0 Respiratory nitrate reductase alpha N-terminal BNR_6 PF15899.5 CAR26033.1 - 0.27 11.4 5.2 31 5.0 0.1 5.1 4 0 0 4 4 4 0 BNR-Asp box repeat adh_short_C2 PF13561.6 CAR26034.1 - 1.3e-37 129.6 0.0 1.6e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR26034.1 - 3.3e-29 101.7 0.0 4e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR26034.1 - 6.3e-10 39.3 0.2 1.1e-09 38.5 0.1 1.4 2 0 0 2 2 2 1 KR domain Aldolase_II PF00596.21 CAR26035.1 - 3.5e-49 167.3 0.1 5.2e-49 166.7 0.1 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans_2 PF11951.8 CAR26036.1 - 3.7e-09 35.9 0.1 8.9e-09 34.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR26036.1 - 5.8e-07 29.5 11.0 1.6e-06 28.1 11.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 CAR26036.1 - 0.25 11.1 5.7 0.18 11.6 3.3 2.0 2 0 0 2 2 2 0 Integrin plexin domain MFS_1 PF07690.16 CAR26037.1 - 1.6e-30 106.2 24.5 1.6e-30 106.2 24.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Holin_SPP1 PF04688.13 CAR26037.1 - 0.54 10.5 2.2 0.73 10.0 0.3 2.2 2 0 0 2 2 2 0 SPP1 phage holin Peptidase_M20 PF01546.28 CAR26038.1 - 0.022 14.4 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.28 CAR26039.1 - 1.8e-30 106.2 0.0 2.8e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR26039.1 - 1.6e-05 24.8 0.0 3.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CAR26039.1 - 2.1e-05 24.3 0.0 3.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Epimerase PF01370.21 CAR26040.1 - 1.5e-22 80.2 0.0 2.9e-22 79.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR26040.1 - 9.3e-14 51.1 0.0 1.4e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CAR26040.1 - 8e-13 48.5 0.0 1.7e-12 47.4 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CAR26040.1 - 1.1e-11 44.4 0.0 5.1e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 CAR26040.1 - 8.3e-09 35.6 0.0 1.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CAR26040.1 - 1.6e-07 31.0 0.0 3.8e-05 23.2 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase Polysacc_synt_2 PF02719.15 CAR26040.1 - 4.2e-06 26.1 0.0 3.3e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CAR26040.1 - 0.00011 21.9 0.2 0.00092 18.8 0.2 2.4 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 CAR26040.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CAR26040.1 - 0.062 12.4 0.0 0.47 9.5 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short_C2 PF13561.6 CAR26040.1 - 0.1 12.1 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Mito_carr PF00153.27 CAR26041.1 - 6.9e-60 199.0 1.3 1.8e-20 72.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CAR26042.1 - 1.3e-44 150.0 6.3 4.4e-19 68.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Polysacc_deac_1 PF01522.21 CAR26043.1 - 1.5e-27 96.0 0.0 2.3e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CAR26043.1 - 4.3e-05 22.9 0.0 5.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 GRIP PF01465.20 CAR26044.1 - 2.3e-13 49.8 0.1 5.9e-13 48.5 0.1 1.8 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 CAR26044.1 - 2.2e-06 26.8 143.1 0.0026 16.7 12.9 6.2 2 2 4 6 6 6 5 Spc7 kinetochore protein ATG16 PF08614.11 CAR26044.1 - 5.2e-06 26.8 147.9 0.097 12.9 22.2 8.3 1 1 7 8 8 8 5 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 CAR26044.1 - 0.0011 19.0 145.6 0.047 13.8 8.9 8.7 2 2 6 8 8 8 6 TPR/MLP1/MLP2-like protein EzrA PF06160.12 CAR26044.1 - 0.0024 16.1 17.1 0.0024 16.1 17.1 5.3 4 2 1 5 5 5 4 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 CAR26044.1 - 0.0025 18.0 18.2 0.0025 18.0 18.2 7.5 2 2 5 8 8 8 2 Fibrinogen alpha/beta chain family SlyX PF04102.12 CAR26044.1 - 0.0036 17.9 6.4 0.0036 17.9 6.4 11.4 4 2 8 12 12 12 3 SlyX IFT57 PF10498.9 CAR26044.1 - 0.013 14.4 126.4 0.13 11.2 6.2 6.2 1 1 2 5 5 5 0 Intra-flagellar transport protein 57 KxDL PF10241.9 CAR26044.1 - 0.02 15.2 4.5 0.02 15.2 4.5 10.1 4 4 6 11 11 10 0 Uncharacterized conserved protein Filament PF00038.21 CAR26044.1 - 0.029 13.9 117.6 0.027 14.1 27.3 5.6 2 1 1 4 4 4 0 Intermediate filament protein HrpB7 PF09486.10 CAR26044.1 - 0.14 12.6 49.1 2.8 8.3 2.6 6.4 3 2 1 5 5 5 0 Bacterial type III secretion protein (HrpB7) PLAC9 PF15205.6 CAR26044.1 - 0.98 9.9 3.8 49 4.4 0.1 4.3 3 1 1 4 4 4 0 Placenta-specific protein 9 Atg14 PF10186.9 CAR26044.1 - 1.9 7.5 135.1 0.021 13.9 20.4 6.6 1 1 5 6 6 5 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 CAR26044.1 - 4.1 7.4 103.6 0.11 12.5 8.1 8.7 2 2 6 9 9 9 0 Laminin Domain II Golgin_A5 PF09787.9 CAR26044.1 - 4.8 6.6 136.0 0.86 9.0 39.4 5.3 1 1 2 4 4 4 0 Golgin subfamily A member 5 RasGEF PF00617.19 CAR26045.1 - 2.9e-54 184.0 4.0 6e-54 182.9 0.0 2.9 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 CAR26045.1 - 5.4e-21 74.8 0.1 2.7e-20 72.5 0.1 2.3 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 CAR26045.1 - 2.1e-09 37.1 0.0 4.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CAR26045.1 - 2.2e-07 30.4 0.0 4.7e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CAR26045.1 - 2.9e-07 30.1 0.0 7.2e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain GAGA_bind PF06217.12 CAR26045.1 - 0.02 15.2 0.6 0.074 13.3 0.6 1.9 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3425 PF11905.8 CAR26045.1 - 0.074 13.0 0.1 0.69 9.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3425) DNA_binding_1 PF01035.20 CAR26045.1 - 0.079 13.1 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain TFIIB PF00382.19 CAR26046.1 - 2.1e-40 136.6 1.7 3e-26 91.3 1.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CAR26046.1 - 1.4e-13 50.1 0.7 2.8e-13 49.1 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 CAR26046.1 - 0.12 11.8 0.5 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF1456 PF07308.13 CAR26046.1 - 0.19 12.1 0.4 0.5 10.7 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) tRNA-synt_2 PF00152.20 CAR26047.1 - 2.5e-78 263.4 0.2 2.5e-78 263.4 0.2 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAR26047.1 - 2.6e-07 30.5 0.1 5.5e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CAR26047.1 - 0.025 14.1 0.2 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) FAM178 PF14816.6 CAR26047.1 - 0.32 9.9 2.5 0.46 9.4 2.5 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 NARP1 PF12569.8 CAR26047.1 - 0.79 8.6 9.9 1.2 8.0 9.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cytadhesin_P30 PF07271.11 CAR26047.1 - 2.1 7.9 3.3 3.9 6.9 3.3 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 CHCH PF06747.13 CAR26048.1 - 0.00058 19.9 2.0 0.00098 19.2 2.0 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 CAR26048.1 - 0.026 14.5 1.5 0.036 14.1 1.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 CAR26048.1 - 0.052 13.8 3.6 0.095 13.0 3.6 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 CAR26048.1 - 0.12 12.4 3.0 0.19 11.7 3.0 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 CAR26048.1 - 0.25 11.7 3.0 4.6 7.7 0.4 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pkinase PF00069.25 CAR26049.1 - 1.1e-37 129.9 0.0 1.3e-36 126.3 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR26049.1 - 3e-16 59.5 0.0 6.2e-16 58.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CAR26049.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribonucleas_3_3 PF14622.6 CAR26051.1 - 9.1e-21 74.3 0.0 1.6e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CAR26051.1 - 3.9e-05 24.2 0.1 0.00012 22.6 0.0 1.9 2 1 0 2 2 2 1 Ribonuclease III domain ARTD15_N PF18084.1 CAR26051.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 ARTD15 N-terminal domain GIT_SHD PF08518.11 CAR26052.1 - 2.5e-24 84.6 8.7 9.1e-13 47.6 0.4 3.4 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 CAR26052.1 - 1.5e-06 28.3 0.5 1.5e-06 28.3 0.5 2.4 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term HALZ PF02183.18 CAR26052.1 - 3.8e-06 27.0 4.7 0.0034 17.6 0.3 3.1 2 0 0 2 2 2 2 Homeobox associated leucine zipper bZIP_1 PF00170.21 CAR26052.1 - 0.0044 17.1 5.0 1.1 9.4 0.3 3.2 2 0 0 2 2 2 2 bZIP transcription factor CCDC92 PF14916.6 CAR26052.1 - 0.007 16.1 0.1 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 Coiled-coil domain of unknown function bZIP_2 PF07716.15 CAR26052.1 - 0.028 14.5 4.9 2.9 8.0 0.3 3.3 2 0 0 2 2 2 0 Basic region leucine zipper APC_N_CC PF16689.5 CAR26052.1 - 0.045 13.8 3.1 0.057 13.5 0.2 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Shugoshin_N PF07558.11 CAR26052.1 - 0.094 12.6 3.8 0.71 9.8 0.4 2.6 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 CAR26052.1 - 0.098 12.4 8.9 1.6 8.6 0.4 3.7 3 0 0 3 3 2 0 Septum formation initiator FlaC_arch PF05377.11 CAR26052.1 - 0.3 11.5 5.0 1.3 9.4 0.6 3.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) JIP_LZII PF16471.5 CAR26052.1 - 0.61 10.3 10.6 0.66 10.2 0.4 3.2 2 1 1 3 3 2 0 JNK-interacting protein leucine zipper II DUF3484 PF11983.8 CAR26052.1 - 1.9 9.6 15.8 16 6.7 7.1 5.2 3 0 0 3 3 3 0 Membrane-attachment and polymerisation-promoting switch Cep57_CLD_2 PF14197.6 CAR26052.1 - 9.8 6.3 11.5 4.4 7.5 6.8 3.0 2 1 0 2 2 1 0 Centrosome localisation domain of PPC89 E1-E2_ATPase PF00122.20 CAR26053.1 - 1.3e-46 158.4 0.1 1.2e-45 155.2 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CAR26053.1 - 6.5e-30 105.0 0.0 1.1e-29 104.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CAR26053.1 - 1.5e-24 86.2 2.4 1.4e-09 38.3 0.1 5.6 5 0 0 5 5 5 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CAR26053.1 - 7.4e-07 29.2 0.0 0.00028 20.7 0.1 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAR26053.1 - 3.7e-06 27.5 0.0 7.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAR26053.1 - 0.0001 22.5 0.0 0.00024 21.2 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DpaA_N PF16924.5 CAR26053.1 - 0.028 14.5 0.0 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain SNAD4 PF18750.1 CAR26053.1 - 0.41 10.8 2.2 2.8 8.1 0.7 2.9 2 1 1 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 4 DUF678 PF05077.12 CAR26053.1 - 0.54 10.4 2.3 27 5.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF678) DUF3795 PF12675.7 CAR26053.1 - 5.5 7.5 7.2 8.4 6.9 2.1 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3795) Septin PF00735.18 CAR26054.1 - 1.1e-109 366.1 0.6 1.1e-109 366.1 0.6 2.0 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CAR26054.1 - 3.3e-05 23.9 0.2 3.3e-05 23.9 0.2 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Exonuc_VII_L PF02601.15 CAR26054.1 - 0.013 15.1 6.6 0.019 14.5 6.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_16 PF13191.6 CAR26054.1 - 0.015 15.7 0.5 0.048 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DASH_Dad1 PF08649.10 CAR26054.1 - 0.12 12.5 0.0 0.54 10.5 0.0 2.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 GTP_EFTU PF00009.27 CAR26054.1 - 0.42 10.1 4.5 0.83 9.2 0.0 2.9 2 2 0 2 2 2 0 Elongation factor Tu GTP binding domain FapA PF03961.13 CAR26054.1 - 2.5 6.6 9.5 4.3 5.8 9.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A RsgA_GTPase PF03193.16 CAR26054.1 - 2.6 7.9 10.2 0.5 10.3 2.2 3.1 3 1 0 3 3 3 0 RsgA GTPase Dynamin_N PF00350.23 CAR26054.1 - 3.7 7.6 8.7 5.4 7.0 0.8 3.3 2 1 0 2 2 2 0 Dynamin family DUF883 PF05957.13 CAR26054.1 - 4.1 8.1 6.3 4.3 8.0 3.9 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) SHNi-TPR PF10516.9 CAR26055.1 - 6.3e-08 31.9 0.4 6.3e-08 31.9 0.4 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_16 PF13432.6 CAR26055.1 - 2.9e-05 24.6 2.5 0.00056 20.5 0.8 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAR26055.1 - 0.00011 22.3 0.5 0.079 13.1 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR26055.1 - 0.00039 20.9 1.1 0.00039 20.9 1.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAR26055.1 - 0.00074 19.8 1.5 0.063 13.6 0.2 3.4 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAR26055.1 - 0.0016 19.1 3.6 0.052 14.4 0.2 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAR26055.1 - 0.0032 17.5 7.4 3 8.2 0.3 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR26055.1 - 0.0065 16.8 1.8 0.11 12.9 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAR26055.1 - 0.0069 16.0 2.5 0.026 14.2 0.9 2.5 2 0 0 2 2 2 1 TPR repeat TPR_6 PF13174.6 CAR26055.1 - 0.018 15.6 3.9 1.4 9.7 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAR26055.1 - 0.023 14.9 7.5 0.68 10.3 0.0 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAR26055.1 - 0.047 13.7 3.5 6 7.1 0.1 3.8 2 2 0 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR26055.1 - 0.22 11.7 2.6 0.31 11.3 0.7 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 LMBR1 PF04791.16 CAR26055.1 - 0.46 9.3 1.0 0.73 8.7 1.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein TPR_1 PF00515.28 CAR26055.1 - 1.8 8.5 9.0 21 5.1 0.3 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat UPF0121 PF03661.13 CAR26056.1 - 1.7e-23 83.3 10.9 2.2e-23 82.9 10.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) HSP70 PF00012.20 CAR26057.1 - 2.9e-261 867.9 7.6 3.2e-261 867.8 7.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR26057.1 - 1.2e-16 60.5 0.0 2.3e-15 56.3 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CAR26057.1 - 0.0045 16.7 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CAR26057.1 - 0.0054 17.1 1.9 6.4 7.3 0.0 3.8 3 2 0 3 3 3 1 Cell division protein FtsA DDR PF08841.10 CAR26057.1 - 0.032 13.2 0.4 0.17 10.8 0.1 2.0 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CAR26057.1 - 0.057 12.7 0.2 0.18 11.0 0.2 1.9 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase SWI-SNF_Ssr4 PF08549.10 CAR26057.1 - 0.72 8.4 7.6 1.4 7.5 0.1 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) NPR3 PF03666.13 CAR26058.1 - 5.9e-171 569.4 0.3 5.9e-171 569.4 0.3 2.8 3 0 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.11 CAR26058.1 - 0.00049 19.0 1.2 0.05 12.4 0.5 2.3 2 0 0 2 2 2 2 Nitrogen permease regulator 2 RRM_1 PF00076.22 CAR26059.1 - 5.7e-28 96.5 5.9 3.7e-14 52.3 0.3 4.3 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR26059.1 - 0.014 15.4 0.1 6.9 6.8 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif AAA_2 PF07724.14 CAR26060.1 - 2.4e-46 158.0 0.0 9.9e-45 152.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CAR26060.1 - 6.8e-27 93.4 0.3 6.8e-27 93.4 0.3 3.1 1 1 2 3 3 3 1 AAA lid domain AAA PF00004.29 CAR26060.1 - 4.5e-25 88.6 0.2 8.9e-14 52.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CAR26060.1 - 4.1e-24 84.4 1.3 4.1e-24 84.4 1.3 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 CAR26060.1 - 2.1e-17 63.0 3.9 1.3e-11 44.4 0.4 3.1 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 CAR26060.1 - 3.1e-16 59.6 0.1 2.4e-08 34.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CAR26060.1 - 3.9e-11 42.9 0.1 3.2e-08 33.5 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 CAR26060.1 - 4.1e-09 37.0 6.2 0.00026 21.4 0.0 5.2 5 1 1 6 6 5 2 AAA ATPase domain AAA_22 PF13401.6 CAR26060.1 - 7.2e-07 29.6 1.6 0.14 12.4 0.1 4.4 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.6 CAR26060.1 - 1.8e-06 28.0 0.0 0.077 13.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 CAR26060.1 - 7.7e-06 25.4 0.1 0.0033 16.8 0.0 3.9 2 1 1 3 3 3 1 Bacterial TniB protein NACHT PF05729.12 CAR26060.1 - 8.1e-05 22.6 0.1 0.63 10.0 0.0 2.8 2 0 0 2 2 2 2 NACHT domain TIP49 PF06068.13 CAR26060.1 - 0.00012 21.4 5.1 0.043 13.0 0.0 4.0 4 0 0 4 4 4 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CAR26060.1 - 0.00013 21.5 0.0 0.59 9.5 0.0 3.6 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CAR26060.1 - 0.00031 20.3 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 CAR26060.1 - 0.00054 19.7 0.0 0.27 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 CAR26060.1 - 0.002 18.0 0.0 0.23 11.3 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CAR26060.1 - 0.0043 16.4 1.7 0.32 10.2 0.0 3.6 3 1 1 4 4 4 1 Zeta toxin AAA_33 PF13671.6 CAR26060.1 - 0.0098 16.1 5.2 0.23 11.6 0.0 4.1 4 0 0 4 4 3 1 AAA domain Torsin PF06309.11 CAR26060.1 - 0.01 15.9 0.0 0.054 13.6 0.0 2.1 2 0 0 2 2 2 0 Torsin IstB_IS21 PF01695.17 CAR26060.1 - 0.019 14.7 0.0 0.88 9.3 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 CAR26060.1 - 0.022 15.0 0.0 14 6.0 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CAR26060.1 - 0.024 14.7 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PEPCK_ATP PF01293.20 CAR26060.1 - 0.029 13.0 0.0 0.066 11.9 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase AAA_19 PF13245.6 CAR26060.1 - 0.054 13.8 2.4 1.2 9.4 0.4 3.6 2 2 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CAR26060.1 - 0.071 13.0 0.0 5.1 7.0 0.0 2.9 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.18 CAR26060.1 - 0.13 11.9 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CAR26060.1 - 0.15 12.0 10.4 3.2 7.6 0.1 4.5 3 3 2 5 5 3 0 ATPase domain predominantly from Archaea OEP PF02321.18 CAR26060.1 - 0.39 10.5 10.6 1.4 8.7 10.6 2.1 1 0 0 1 1 1 0 Outer membrane efflux protein ABC_tran PF00005.27 CAR26060.1 - 0.72 10.4 5.9 7.4 7.1 0.0 3.9 3 1 0 3 3 2 0 ABC transporter DUF4407 PF14362.6 CAR26060.1 - 1.1 8.5 10.1 2.9 7.2 10.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 CAR26060.1 - 2.5 7.1 11.4 5 6.1 11.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 CAR26060.1 - 4.9 6.0 18.8 16 4.3 18.7 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CAR26060.1 - 9.1 4.1 9.4 15 3.3 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fe-S_biosyn PF01521.20 CAR26061.1 - 1.5e-17 63.8 0.0 2.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DAG_kinase_N PF14513.6 CAR26061.1 - 0.012 15.8 0.8 0.017 15.4 0.8 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus TMEM51 PF15345.6 CAR26061.1 - 0.13 12.1 3.2 0.18 11.6 3.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Presenilin PF01080.17 CAR26061.1 - 0.46 9.2 1.0 0.49 9.1 1.0 1.1 1 0 0 1 1 1 0 Presenilin BRF1 PF07741.13 CAR26061.1 - 5 7.5 9.6 5.5 7.4 8.9 1.4 1 1 0 1 1 1 0 Brf1-like TBP-binding domain MFS_1 PF07690.16 CAR26062.1 - 1.3e-36 126.3 32.0 1.3e-36 126.3 32.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR26062.1 - 3.4e-12 46.0 7.8 3.4e-12 46.0 7.8 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 CAR26062.1 - 0.00034 19.2 5.6 0.00067 18.2 5.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RICTOR_V PF14668.6 CAR26062.1 - 0.14 12.4 0.5 0.37 11.1 0.5 1.7 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Peptidase_M24 PF00557.24 CAR26063.1 - 8.9e-46 156.2 0.0 1.3e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 CAR26063.1 - 3.2e-42 144.4 0.4 6.9e-42 143.3 0.2 1.7 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CAR26063.1 - 6.5e-21 74.2 1.6 1.5e-20 73.0 0.7 2.1 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CAR26063.1 - 3e-08 34.4 0.0 1e-07 32.7 0.0 2.0 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain P4Ha_N PF08336.11 CAR26063.1 - 0.15 12.1 1.2 0.37 10.8 1.2 1.7 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Phosphodiest PF01663.22 CAR26064.1 - 5.5e-15 55.8 0.3 9.5e-15 55.0 0.3 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CAR26064.1 - 0.0031 16.9 2.0 0.0041 16.5 1.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 CAR26064.1 - 0.0048 16.3 0.1 0.0084 15.5 0.1 1.3 1 0 0 1 1 1 1 Sulfatase SOBP PF15279.6 CAR26065.1 - 1.8 9.1 22.2 0.52 10.9 16.3 2.0 2 0 0 2 2 2 0 Sine oculis-binding protein DUF572 PF04502.13 CAR26066.1 - 1.3e-48 166.3 9.5 1.6e-48 166.0 9.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Aconitase PF00330.20 CAR26066.1 - 0.049 12.6 0.1 0.049 12.6 0.1 1.8 2 0 0 2 2 2 0 Aconitase family (aconitate hydratase) bZIP_1 PF00170.21 CAR26067.1 - 0.0003 20.8 20.7 0.00055 20.0 20.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CAR26067.1 - 0.0087 16.6 11.8 0.017 15.7 11.8 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Exonuc_VII_L PF02601.15 CAR26067.1 - 0.011 15.3 0.8 0.014 15.0 0.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CASP_C PF08172.12 CAR26067.1 - 0.018 14.4 3.7 0.028 13.8 3.7 1.3 1 0 0 1 1 1 0 CASP C terminal Glutaredoxin2_C PF04399.13 CAR26067.1 - 0.022 14.6 2.4 0.045 13.6 2.4 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain TPR_MLP1_2 PF07926.12 CAR26067.1 - 0.034 14.2 12.6 0.06 13.4 12.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 CAR26067.1 - 0.045 14.4 3.0 0.052 14.2 1.8 1.7 1 1 0 1 1 1 0 Initiation control protein YabA V_ATPase_I PF01496.19 CAR26067.1 - 0.073 11.0 2.1 0.083 10.8 2.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FapA PF03961.13 CAR26067.1 - 0.39 9.3 3.4 0.6 8.6 3.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A CUE PF02845.16 CAR26068.1 - 2.5e-09 36.7 0.3 0.0045 16.7 0.2 3.4 3 0 0 3 3 3 2 CUE domain Smr PF01713.21 CAR26068.1 - 3.5e-07 30.5 0.0 9.8e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Smr domain CENP-C_C PF11699.8 CAR26069.1 - 1.2e-26 92.7 1.6 2.1e-26 91.9 1.6 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 CAR26069.1 - 6.4e-06 25.8 0.0 1.6e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Mif2_N PF15624.6 CAR26069.1 - 1.8e-05 25.4 4.0 1.8e-05 25.4 4.0 4.4 4 2 0 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal MannoseP_isomer PF01050.18 CAR26069.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase AT_hook PF02178.19 CAR26069.1 - 0.55 10.3 6.1 1.5 8.9 6.1 1.8 1 0 0 1 1 1 0 AT hook motif Pkinase PF00069.25 CAR26070.1 - 1.2e-72 244.5 0.0 1.8e-72 243.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR26070.1 - 3.2e-48 164.3 0.0 5.2e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CAR26070.1 - 1.4e-21 76.6 0.0 4.9e-21 74.8 0.0 2.1 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 CAR26070.1 - 2.8e-05 23.6 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAR26070.1 - 0.00034 19.5 1.2 0.00034 19.5 1.2 2.6 2 2 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CAR26070.1 - 0.21 11.5 0.0 1.2 9.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family HECT PF00632.25 CAR26071.1 - 1.5e-71 241.4 0.1 2.4e-71 240.7 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RL10P_insert PF17777.1 CAR26072.1 - 1.1e-19 70.1 0.0 1.8e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 CAR26072.1 - 2.8e-18 65.9 0.0 4.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_S2 PF00318.20 CAR26074.1 - 9.8e-69 230.9 0.0 4.9e-68 228.6 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 EzrA PF06160.12 CAR26074.1 - 0.0024 16.1 0.8 0.0032 15.7 0.8 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA MazG PF03819.17 CAR26074.1 - 0.0076 16.4 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain ApoLp-III PF07464.11 CAR26074.1 - 0.013 15.5 1.6 0.034 14.2 1.3 1.8 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Tudor_RapA PF18337.1 CAR26074.1 - 0.027 14.6 0.0 0.089 13.0 0.0 1.9 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain FAM76 PF16046.5 CAR26074.1 - 0.12 11.7 0.3 0.19 11.1 0.3 1.3 1 0 0 1 1 1 0 FAM76 protein TRAM_LAG1_CLN8 PF03798.16 CAR26075.1 - 4.4e-35 121.2 25.2 4.4e-35 121.2 25.2 2.2 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.11 CAR26075.1 - 6.9e-23 80.1 0.5 1.7e-22 78.8 0.5 1.8 1 0 0 1 1 1 1 TRAM1-like protein VHS PF00790.19 CAR26076.1 - 1.4e-35 122.2 0.1 3.9e-35 120.8 0.1 1.8 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 CAR26076.1 - 1.1e-14 53.8 0.0 1.8e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CAR26076.1 - 4.3e-12 45.5 0.1 1.1e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 CAR26076.1 - 6.3e-11 42.0 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Hrs_helical PF12210.8 CAR26076.1 - 2.8e-06 27.8 3.1 0.00016 22.1 0.1 2.4 2 0 0 2 2 2 1 Hepatocyte growth factor-regulated tyrosine kinase substrate GAT PF03127.14 CAR26076.1 - 0.00086 19.6 0.1 0.00086 19.6 0.1 2.9 3 0 0 3 3 3 1 GAT domain Tnp_DNA_bind PF14706.6 CAR26076.1 - 0.12 12.3 0.1 27 4.7 0.1 3.2 3 0 0 3 3 3 0 Transposase DNA-binding FAM76 PF16046.5 CAR26076.1 - 0.18 11.2 3.8 0.48 9.7 0.2 2.3 2 0 0 2 2 2 0 FAM76 protein F-actin_cap_A PF01267.17 CAR26077.1 - 4.9e-79 265.5 2.2 5.5e-79 265.3 2.2 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Flu_NS2 PF00601.19 CAR26078.1 - 0.0083 16.4 0.1 0.011 16.1 0.1 1.2 1 0 0 1 1 1 1 Influenza non-structural protein (NS2) Polysacc_deac_2 PF04748.13 CAR26078.1 - 0.034 13.3 0.1 0.038 13.2 0.1 1.1 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF507 PF04368.13 CAR26078.1 - 0.046 13.6 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF507) DUF2207 PF09972.9 CAR26078.1 - 0.1 11.4 0.1 0.11 11.3 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_L14e PF01929.17 CAR26079.1 - 3.5e-31 107.5 4.0 5.3e-31 106.9 4.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CAR26079.1 - 0.097 12.7 0.8 0.097 12.7 0.8 1.6 2 0 0 2 2 2 0 KOW motif TFIIS_M PF07500.14 CAR26080.1 - 1e-23 84.0 2.2 1.8e-23 83.2 2.2 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 CAR26080.1 - 1.9e-10 40.4 8.2 3.4e-10 39.7 8.2 1.4 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.13 CAR26080.1 - 0.0035 17.3 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 SPOC domain Prok-RING_1 PF14446.6 CAR26080.1 - 0.14 12.1 10.5 0.12 12.3 1.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD_4 PF16866.5 CAR26080.1 - 1.1 9.4 6.3 3 8.0 6.3 1.8 1 0 0 1 1 1 0 PHD-finger PHD_2 PF13831.6 CAR26080.1 - 1.4 8.5 4.9 4.8 6.8 4.9 1.9 1 1 0 1 1 1 0 PHD-finger PAP2_3 PF14378.6 CAR26081.1 - 1.1e-24 87.2 9.3 1.1e-24 87.2 9.3 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CAR26081.1 - 7.8e-11 41.9 3.5 7.8e-11 41.9 3.5 2.4 2 0 0 2 2 2 2 PAP2 superfamily Ribosomal_S6 PF01250.17 CAR26082.1 - 1.5e-25 89.3 0.0 2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Snf7 PF03357.21 CAR26083.1 - 2.1e-30 105.6 24.7 7e-30 103.9 22.4 1.9 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.14 CAR26083.1 - 6.6e-05 22.9 8.3 9e-05 22.5 8.3 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DEPP PF15343.6 CAR26083.1 - 0.071 13.2 4.0 0.045 13.8 2.0 1.8 2 0 0 2 2 2 0 Decidual protein induced by progesterone family Uds1 PF15456.6 CAR26083.1 - 1 9.5 14.1 0.021 15.0 1.6 2.5 1 1 1 2 2 2 0 Up-regulated During Septation Hpt PF01627.23 CAR26083.1 - 1.2 9.5 5.3 0.23 11.8 0.5 2.3 2 1 0 2 2 2 0 Hpt domain DUF1002 PF06207.11 CAR26083.1 - 4.6 6.7 13.9 0.039 13.5 3.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1002) DUF3958 PF13125.6 CAR26083.1 - 5.8 7.2 15.5 0.9 9.8 9.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3958) YlqD PF11068.8 CAR26083.1 - 9.4 6.6 22.2 0.49 10.8 9.6 2.5 1 1 2 3 3 3 0 YlqD protein APS_kinase PF01583.20 CAR26084.1 - 4.8e-75 250.8 0.0 5.8e-75 250.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 CAR26084.1 - 1.7e-07 31.5 0.0 3.2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CAR26084.1 - 0.00039 20.0 0.0 0.00044 19.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CAR26084.1 - 0.00051 20.6 0.1 0.0012 19.4 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.6 CAR26084.1 - 0.00094 18.9 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.20 CAR26084.1 - 0.0096 15.1 0.2 0.031 13.4 0.1 1.7 1 1 1 2 2 2 1 G-protein alpha subunit CPT PF07931.12 CAR26084.1 - 0.014 15.3 0.5 0.25 11.1 0.5 2.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 CAR26084.1 - 0.037 14.4 0.0 0.041 14.3 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 CAR26084.1 - 0.065 13.0 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 CAR26084.1 - 0.082 13.4 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 CAR26084.1 - 0.096 12.0 0.0 0.16 11.2 0.0 1.3 1 1 0 1 1 1 0 Zeta toxin CbiA PF01656.23 CAR26084.1 - 0.12 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain YozD PF14162.6 CAR26084.1 - 0.16 12.3 0.2 0.4 11.0 0.0 1.7 2 0 0 2 2 2 0 YozD-like protein Dynamin_M PF01031.20 CAR26085.1 - 8.7e-98 327.0 0.1 2.4e-97 325.6 0.0 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CAR26085.1 - 1.9e-55 187.5 0.1 4.3e-55 186.3 0.1 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CAR26085.1 - 1.5e-28 98.8 4.8 3.6e-28 97.5 4.8 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CAR26085.1 - 8.8e-05 22.6 0.1 0.00034 20.7 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CAR26085.1 - 0.084 13.3 0.0 0.4 11.1 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 CAR26085.1 - 0.44 10.2 8.8 1.8 8.2 0.8 2.8 3 0 0 3 3 3 0 AAA ATPase domain PAP_central PF04928.17 CAR26086.1 - 2.1e-110 367.6 0.0 3.3e-110 366.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CAR26086.1 - 1.8e-54 183.9 3.9 2.1e-54 183.7 2.5 1.8 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CAR26086.1 - 9e-14 51.5 1.7 1.3e-13 51.0 0.0 2.2 2 1 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 CAR26086.1 - 0.0078 16.3 0.1 0.052 13.6 0.0 2.4 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase Oxysterol_BP PF01237.18 CAR26087.1 - 9.4e-84 281.4 0.2 6.4e-82 275.4 0.2 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Ribosomal_L50 PF10501.9 CAR26090.1 - 5.2e-29 100.6 0.2 1.6e-28 99.0 0.2 1.8 1 0 0 1 1 1 1 Ribosomal subunit 39S PAS_10 PF13596.6 CAR26090.1 - 0.15 12.7 1.9 0.32 11.6 0.1 2.3 2 1 0 2 2 2 0 PAS domain LAMTOR PF15454.6 CAR26091.1 - 3.6e-21 75.5 2.5 3.6e-21 75.5 2.5 1.5 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Nkap_C PF06047.11 CAR26091.1 - 0.023 14.8 2.2 0.15 12.2 0.3 2.0 2 0 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain PPR_1 PF12854.7 CAR26091.1 - 0.07 12.9 0.3 0.12 12.1 0.3 1.4 1 0 0 1 1 1 0 PPR repeat Bromodomain PF00439.25 CAR26092.1 - 4.3e-31 106.8 5.6 2.1e-19 69.3 0.2 2.5 2 0 0 2 2 2 2 Bromodomain Glyco_transf_15 PF01793.16 CAR26093.1 - 3.7e-119 397.8 9.5 4.7e-119 397.4 9.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase QCR10 PF09796.9 CAR26094.1 - 2.5e-27 94.7 0.5 3e-27 94.4 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) RhodobacterPufX PF11511.8 CAR26094.1 - 0.055 13.1 1.9 0.1 12.2 1.6 1.6 1 1 0 1 1 1 0 Intrinsic membrane protein PufX adh_short PF00106.25 CAR26095.1 - 4.4e-82 274.3 10.0 4.8e-41 140.4 2.2 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CAR26095.1 - 3.4e-64 216.6 3.9 3.5e-32 111.8 0.1 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR26095.1 - 1.9e-31 109.4 3.2 1.9e-15 57.2 0.4 2.5 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 CAR26095.1 - 3.1e-30 104.3 0.0 5.7e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CAR26095.1 - 1.5e-07 31.6 0.0 0.0011 19.2 0.0 2.7 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase NAD_binding_8 PF13450.6 CAR26095.1 - 0.12 12.6 0.7 0.42 10.9 0.7 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain XdhC_CoxI PF02625.16 CAR26095.1 - 0.16 12.1 0.4 0.39 10.9 0.4 1.6 1 0 0 1 1 1 0 XdhC and CoxI family PglL_A PF15864.5 CAR26095.1 - 1.2 9.0 7.9 5.5 6.8 1.0 2.6 2 0 0 2 2 2 0 Protein glycosylation ligase Adap_comp_sub PF00928.21 CAR26096.1 - 1.2e-32 113.3 0.4 2.9e-32 112.1 0.4 1.6 1 1 0 1 1 1 1 Adaptor complexes medium subunit family SNF5 PF04855.12 CAR26097.1 - 2.6e-51 174.7 3.3 2.6e-51 174.7 3.3 5.0 3 2 0 3 3 3 1 SNF5 / SMARCB1 / INI1 DUF2370 PF10176.9 CAR26098.1 - 3.1e-79 265.8 0.0 3.7e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Mito_carr PF00153.27 CAR26099.1 - 1.6e-57 191.4 2.5 3.8e-20 71.6 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CAR26099.1 - 0.016 14.4 0.2 2.8 7.0 0.0 2.7 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Tim17 PF02466.19 CAR26099.1 - 0.016 15.5 2.0 2.5 8.5 0.0 3.3 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.27 CAR26100.1 - 3.7e-61 203.1 0.6 1.1e-22 79.7 0.0 3.7 3 2 1 4 4 4 3 Mitochondrial carrier protein ThiF PF00899.21 CAR26101.1 - 1.6e-44 152.1 0.0 2.4e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CAR26101.1 - 0.00059 20.1 0.2 0.0027 18.0 0.2 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CAR26101.1 - 0.0025 17.9 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CAR26101.1 - 0.027 14.9 0.1 0.055 13.9 0.1 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 CAR26101.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 CAR26101.1 - 0.097 12.2 0.3 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 CAR26101.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TFIIE_alpha PF02002.17 CAR26102.1 - 2.5e-34 117.3 0.2 1.1e-33 115.2 0.0 2.1 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 CAR26102.1 - 4e-11 42.2 0.5 1.3e-10 40.6 0.5 2.0 1 0 0 1 1 1 1 TFIIB zinc-binding PTPRCAP PF15713.5 CAR26102.1 - 8.1 6.7 28.1 0.37 11.1 20.8 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DAO PF01266.24 CAR26103.1 - 8.3e-29 101.3 0.0 1e-28 101.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CAR26103.1 - 0.086 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Malic_M PF03949.15 CAR26104.1 - 5.9e-85 284.6 0.0 7.9e-85 284.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CAR26104.1 - 3.5e-63 212.7 0.0 5.3e-63 212.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AA_kinase PF00696.28 CAR26104.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Amino acid kinase family LAGLIDADG_3 PF14528.6 CAR26105.1 - 0.13 12.6 1.8 0.59 10.5 0.3 2.8 2 0 0 2 2 2 0 LAGLIDADG-like domain Spc7 PF08317.11 CAR26105.1 - 1.9 7.3 75.8 0.039 12.8 16.3 4.9 2 1 3 5 5 5 0 Spc7 kinetochore protein NIF PF03031.18 CAR26106.1 - 1.3e-50 171.2 0.1 1.8e-50 170.8 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Molydop_binding PF01568.21 CAR26106.1 - 0.017 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain Leuk-A4-hydro_C PF09127.11 CAR26106.1 - 0.023 14.8 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Acetyltransf_1 PF00583.25 CAR26107.1 - 7.4e-11 42.3 0.0 9.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR26107.1 - 2.1e-09 37.4 0.0 3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR26107.1 - 3.2e-09 37.1 0.0 5.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CAR26107.1 - 0.0016 18.6 0.2 0.0023 18.1 0.2 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAR26107.1 - 0.0075 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 CAR26107.1 - 0.0083 15.6 1.3 0.016 14.7 1.3 1.6 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 CAR26107.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CAR26107.1 - 0.04 14.6 0.1 0.053 14.2 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C2H2 PF00096.26 CAR26108.1 - 5.6e-06 26.5 12.8 1.6e-05 25.1 3.3 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR26108.1 - 1.9e-05 25.1 12.9 0.0007 20.2 3.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 CAR26108.1 - 0.00014 22.1 3.3 0.00035 20.8 3.3 1.7 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_aberr PF17017.5 CAR26108.1 - 0.00051 20.2 0.3 0.00082 19.6 0.3 1.3 1 0 0 1 1 1 1 Aberrant zinc-finger Zn-C2H2_12 PF18112.1 CAR26108.1 - 0.0032 17.9 0.0 0.0098 16.3 0.0 1.8 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain GAGA PF09237.11 CAR26108.1 - 0.032 14.0 1.1 3.7 7.4 0.3 2.4 1 1 1 2 2 2 0 GAGA factor zf-H2C2_2 PF13465.6 CAR26108.1 - 0.04 14.4 12.3 2.4 8.7 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 CAR26108.1 - 0.041 14.2 6.1 1.3 9.4 1.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CAR26108.1 - 0.043 14.1 0.5 0.13 12.5 0.5 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CAR26108.1 - 0.077 13.3 2.0 0.46 10.8 1.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc ribbon DUF2225 PF09986.9 CAR26108.1 - 0.15 11.8 0.9 12 5.5 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_5 PF13909.6 CAR26108.1 - 0.16 11.8 14.4 0.46 10.3 1.1 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain TFIIA PF03153.13 CAR26108.1 - 0.17 11.8 4.0 0.19 11.7 4.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-met PF12874.7 CAR26108.1 - 0.24 11.8 3.8 0.42 11.1 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_9 PF16293.5 CAR26108.1 - 0.26 11.2 1.9 7.6 6.5 0.2 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Cg6151-P PF10233.9 CAR26109.1 - 4.9e-37 126.7 12.1 5.9e-37 126.4 12.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P SLATT_1 PF18181.1 CAR26109.1 - 9.4 6.2 6.2 7.3 6.5 1.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 zinc_ribbon_6 PF14599.6 CAR26110.1 - 3.7e-24 84.5 3.0 3.7e-24 84.5 3.0 5.0 3 1 2 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 CAR26110.1 - 4e-15 56.1 23.9 4e-15 56.1 23.9 4.0 2 1 2 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.6 CAR26110.1 - 7.6e-09 35.8 9.7 7.6e-09 35.8 9.7 5.6 4 2 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAR26110.1 - 0.00016 21.4 9.9 0.00016 21.4 9.9 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR26110.1 - 0.00086 19.2 12.1 0.00086 19.2 12.1 6.4 4 3 2 6 6 6 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CAR26110.1 - 0.0029 17.5 5.5 0.0029 17.5 5.5 5.4 5 2 1 6 6 6 2 Prokaryotic RING finger family 4 HMG_box PF00505.19 CAR26111.1 - 1.1e-30 105.9 15.4 1.5e-17 63.8 4.2 3.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CAR26111.1 - 1.2e-14 54.6 10.4 3.1e-11 43.7 4.1 4.3 4 1 0 4 4 4 2 HMG-box domain CHDNT PF08073.12 CAR26111.1 - 2.4e-10 40.2 0.1 0.00021 21.1 0.0 2.9 2 0 0 2 2 2 2 CHDNT (NUC034) domain Cyt-b5 PF00173.28 CAR26112.1 - 4.1e-20 71.7 0.1 6.1e-20 71.1 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cu_amine_oxid PF01179.20 CAR26113.1 - 1.5e-145 485.2 0.2 1.9e-145 484.9 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 CAR26113.1 - 0.014 15.6 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain dsDNA_bind PF01984.20 CAR26114.1 - 7.5e-23 80.9 0.0 1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PHD PF00628.29 CAR26115.1 - 3.9e-14 52.3 21.5 4.7e-11 42.4 7.6 3.3 2 1 1 3 3 3 2 PHD-finger PHF12_MRG_bd PF16737.5 CAR26115.1 - 0.04 13.7 0.3 0.1 12.4 0.3 1.6 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain PHD_4 PF16866.5 CAR26115.1 - 0.04 14.0 16.4 0.028 14.5 2.3 2.8 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.6 CAR26115.1 - 0.083 13.2 9.6 0.14 12.5 1.6 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain C1_1 PF00130.22 CAR26115.1 - 0.27 11.1 10.5 0.63 10.0 0.7 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 CAR26115.1 - 0.37 10.4 5.4 7.9 6.1 0.3 2.7 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 CAR26115.1 - 5.8 6.6 11.8 9.4 5.9 0.3 3.6 3 0 0 3 3 3 0 PHD-finger Prok-RING_1 PF14446.6 CAR26115.1 - 9.9 6.2 11.0 0.45 10.5 1.1 3.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Cnd1 PF12717.7 CAR26116.1 - 2.3e-05 24.5 6.0 0.00034 20.7 1.4 4.3 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DTHCT PF08070.11 CAR26116.1 - 0.41 11.4 10.2 1.4 9.7 10.2 1.8 1 0 0 1 1 1 0 DTHCT (NUC029) region Form_Nir_trans PF01226.17 CAR26117.1 - 4.6e-57 193.1 18.5 5.6e-57 192.8 18.5 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Arm PF00514.23 CAR26118.1 - 0.023 14.7 0.9 2.2 8.4 0.1 3.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat BRAP2 PF07576.12 CAR26119.1 - 5e-29 100.4 1.0 1.2e-28 99.3 1.0 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CAR26119.1 - 1.4e-21 76.5 6.7 4e-21 75.1 6.7 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CAR26119.1 - 3.5e-09 36.9 11.2 3.5e-09 36.9 11.2 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAR26119.1 - 6.8e-07 29.0 11.6 2e-06 27.5 11.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAR26119.1 - 6.6e-06 25.8 4.9 6.6e-06 25.8 4.9 2.0 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CAR26119.1 - 1.4e-05 25.0 7.9 6.5e-05 22.9 8.1 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAR26119.1 - 1.7e-05 24.6 10.8 5e-05 23.1 10.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CAR26119.1 - 1.7e-05 25.0 8.0 5.4e-05 23.4 8.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CAR26119.1 - 3e-05 23.8 6.9 3e-05 23.8 6.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR26119.1 - 5.2e-05 23.1 9.2 5.2e-05 23.1 9.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CAR26119.1 - 0.0014 18.6 4.7 0.0048 16.9 4.7 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CAR26119.1 - 0.011 15.6 12.3 0.011 15.6 12.3 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CAR26119.1 - 0.019 14.7 8.8 0.047 13.5 8.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UBP_var PF17807.1 CAR26119.1 - 0.039 13.7 0.6 0.096 12.5 0.6 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger Pribosyl_synth PF14572.6 CAR26120.1 - 1.2e-41 142.8 3.4 1.3e-36 126.3 2.0 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CAR26120.1 - 7.4e-39 132.3 0.1 2.1e-38 130.9 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CAR26120.1 - 8e-18 64.5 0.9 2.4e-17 62.9 0.7 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAR26120.1 - 0.027 13.9 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HAD_2 PF13419.6 CAR26121.1 - 1.1e-19 71.2 0.0 1.4e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR26121.1 - 6.3e-11 43.0 0.0 6.8e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CAR26121.1 - 0.0025 17.9 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 CAR26121.1 - 0.026 14.9 0.0 0.032 14.7 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 CAR26122.1 - 4.1e-13 49.0 0.0 8.5e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CAR26122.1 - 0.011 16.3 0.6 0.011 16.3 0.6 3.0 2 1 1 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 Mito_carr PF00153.27 CAR26124.1 - 5.4e-44 148.0 4.9 5.5e-16 58.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Histone_HNS PF00816.21 CAR26124.1 - 0.12 13.2 0.1 0.51 11.2 0.1 1.9 2 0 0 2 2 2 0 H-NS histone family Mito_carr PF00153.27 CAR26125.1 - 9.4e-58 192.2 2.1 1.2e-20 73.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_60s PF00428.19 CAR26126.1 - 4.3e-24 84.9 15.9 5.4e-24 84.6 15.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 CAR26126.1 - 0.27 11.9 2.3 0.38 11.4 2.3 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF2714 PF10896.8 CAR26127.1 - 0.057 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2714) ARTD15_N PF18084.1 CAR26127.1 - 0.059 13.6 1.3 2.3 8.5 0.4 3.1 2 1 0 2 2 2 0 ARTD15 N-terminal domain DUF5572 PF17733.1 CAR26127.1 - 0.059 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5572) BioW PF03744.13 CAR26127.1 - 0.073 12.6 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase DASH_Dad3 PF08656.10 CAR26127.1 - 0.082 13.0 1.4 0.67 10.1 0.2 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad3 Noelin-1 PF12308.8 CAR26127.1 - 0.21 11.6 3.1 0.31 11.0 1.3 2.0 1 1 1 2 2 2 0 Neurogenesis glycoprotein Gpr1_Fun34_YaaH PF01184.19 CAR26128.1 - 3.1e-71 239.2 13.7 3.9e-71 238.9 13.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Reprolysin_4 PF13583.6 CAR26129.1 - 0.037 13.7 1.1 0.054 13.1 1.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like WD40 PF00400.32 CAR26130.1 - 8.8e-09 35.9 7.9 0.0027 18.5 0.3 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 CAR26130.1 - 0.00038 19.2 0.4 0.00062 18.5 0.4 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 SUKH_6 PF14568.6 CAR26130.1 - 0.007 16.8 0.2 0.099 13.1 0.0 2.6 2 0 0 2 2 2 1 SMI1-KNR4 cell-wall PQQ_3 PF13570.6 CAR26130.1 - 0.026 15.0 0.0 0.14 12.7 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain PQQ PF01011.21 CAR26130.1 - 0.17 11.9 0.5 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 PQQ enzyme repeat NMT_C PF02799.15 CAR26131.1 - 7.7e-80 267.3 0.0 1.1e-79 266.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CAR26131.1 - 3.6e-73 244.7 0.0 6.4e-73 243.9 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 CAR26131.1 - 3.4e-07 30.4 0.0 5.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAR26131.1 - 0.0012 19.0 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CAR26131.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CAR26131.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FIT1_2 PF17357.2 CAR26132.1 - 1.9 8.6 20.9 2.1 8.5 0.4 3.2 3 0 0 3 3 3 0 Facilitor Of iron transport 1 and 2 PRELI PF04707.14 CAR26133.1 - 2.3e-50 170.5 0.1 2.7e-50 170.2 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family Fungal_trans_2 PF11951.8 CAR26134.1 - 1.9e-71 240.9 9.7 2.3e-71 240.7 9.7 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR26134.1 - 5.4e-09 36.0 7.4 9.6e-09 35.2 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RB_B PF01857.20 CAR26134.1 - 0.069 13.2 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain Dickkopf_N PF04706.12 CAR26134.1 - 3 8.4 9.1 2.4 8.7 6.7 2.1 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region GATase_2 PF00310.21 CAR26135.1 - 8.7e-171 568.3 0.0 1.2e-170 567.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CAR26135.1 - 9.6e-154 511.9 0.0 1.6e-153 511.2 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CAR26135.1 - 2e-113 378.5 0.0 3.9e-110 367.7 0.0 2.6 2 1 0 2 2 2 2 Glutamate synthase central domain GXGXG PF01493.19 CAR26135.1 - 3.8e-69 232.1 2.2 6.7e-69 231.3 2.2 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 CAR26135.1 - 1.2e-23 83.1 0.1 2.1e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 CAR26135.1 - 7.7e-22 77.9 0.2 3.8e-21 75.6 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAR26135.1 - 3.9e-09 36.6 0.0 1.2e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CAR26135.1 - 4.7e-07 30.3 0.7 3.3e-05 24.3 0.1 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CAR26135.1 - 9.7e-07 28.4 0.0 2.7e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 CAR26135.1 - 8.9e-06 25.2 0.2 0.0054 16.0 0.0 2.9 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAR26135.1 - 1.9e-05 24.2 0.0 4.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CAR26135.1 - 2.1e-05 23.4 1.1 2.9e-05 22.9 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 CAR26135.1 - 4.4e-05 23.2 0.2 0.00051 19.7 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CAR26135.1 - 0.00023 20.4 0.0 0.00042 19.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CAR26135.1 - 0.00051 19.3 0.1 0.0018 17.6 0.1 1.9 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 CAR26135.1 - 0.00057 19.2 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CAR26135.1 - 0.0026 16.9 0.2 0.016 14.3 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FMO-like PF00743.19 CAR26135.1 - 0.0033 15.9 0.2 0.32 9.3 0.0 3.0 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like FMN_dh PF01070.18 CAR26135.1 - 0.0046 16.0 4.8 0.043 12.8 1.1 2.9 3 0 0 3 3 3 1 FMN-dependent dehydrogenase NAD_binding_9 PF13454.6 CAR26135.1 - 0.014 15.4 0.3 0.16 11.9 0.0 2.9 4 0 0 4 4 3 0 FAD-NAD(P)-binding AdoHcyase_NAD PF00670.21 CAR26135.1 - 0.017 15.2 0.8 4.7 7.3 0.0 3.0 3 0 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Lycopene_cycl PF05834.12 CAR26135.1 - 0.041 12.9 0.1 0.073 12.1 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 CAR26135.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 CAR26135.1 - 0.047 13.6 0.0 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GATase_6 PF13522.6 CAR26135.1 - 0.051 13.8 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 Glutamine amidotransferase domain NAD_binding_7 PF13241.6 CAR26135.1 - 0.063 13.7 1.1 2.3 8.7 0.0 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF4538 PF15061.6 CAR26135.1 - 0.069 12.9 0.1 0.18 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) AlaDh_PNT_C PF01262.21 CAR26135.1 - 0.11 11.8 0.5 1.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CAR26135.1 - 0.12 11.7 0.0 2.5 7.5 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 CAR26135.1 - 0.32 10.9 1.2 0.7 9.8 0.0 2.1 2 0 0 2 2 2 0 Rossmann-like domain DUF3602 PF12223.8 CAR26136.1 - 6.1e-19 68.4 11.6 5.4e-11 42.9 0.2 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF3602) GTP1_OBG PF01018.22 CAR26136.1 - 0.058 13.0 1.7 12 5.4 0.1 3.1 3 0 0 3 3 3 0 GTP1/OBG eIF3_subunit PF08597.10 CAR26137.1 - 3.5e-53 181.0 19.1 4.9e-53 180.5 19.1 1.2 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit FAD-oxidase_C PF02913.19 CAR26138.1 - 2e-59 201.2 0.0 3.6e-59 200.4 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CAR26138.1 - 9.7e-38 129.0 0.0 1.8e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Peroxin-13_N PF04088.13 CAR26140.1 - 1.4e-50 171.4 2.4 2.3e-50 170.7 2.4 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 CAR26140.1 - 1.6e-08 34.0 0.0 3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR26140.1 - 3.2e-07 30.1 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR26140.1 - 1.8e-06 27.5 0.0 3.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain MMR1 PF08505.10 CAR26141.1 - 1.1e-75 255.4 34.9 1.1e-75 255.4 34.9 3.4 2 1 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein bZIP_1 PF00170.21 CAR26141.1 - 0.0063 16.6 6.3 0.92 9.6 1.1 2.9 2 0 0 2 2 2 2 bZIP transcription factor BRI3BP PF14965.6 CAR26141.1 - 0.093 12.2 2.2 0.91 9.0 0.2 2.2 2 0 0 2 2 2 0 Negative regulator of p53/TP53 PALP PF00291.25 CAR26143.1 - 1.5e-79 267.5 0.1 2e-79 267.1 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CAR26143.1 - 2.6e-40 136.1 0.0 2.6e-25 88.0 0.0 2.6 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase tRNA-synt_2b PF00587.25 CAR26144.1 - 2.5e-37 128.6 0.0 4.4e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CAR26144.1 - 0.1 12.8 0.0 0.42 10.8 0.0 1.9 1 1 0 1 1 1 0 Anticodon binding domain BET PF17035.5 CAR26144.1 - 0.15 12.3 0.0 3.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Sec61_beta PF03911.16 CAR26145.1 - 2.5e-17 62.6 0.9 3.2e-17 62.3 0.9 1.1 1 0 0 1 1 1 1 Sec61beta family RRM_1 PF00076.22 CAR26146.1 - 1.4e-07 31.2 0.1 2.7e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CLN3 PF02487.17 CAR26146.1 - 0.44 9.5 1.0 0.85 8.6 1.0 1.4 1 0 0 1 1 1 0 CLN3 protein MOZ_SAS PF01853.18 CAR26147.1 - 9.8e-75 250.1 0.2 1.5e-74 249.5 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CAR26147.1 - 8.8e-19 66.9 8.4 8.8e-19 66.9 8.4 1.8 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CAR26147.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cwf_Cwc_15 PF04889.12 CAR26147.1 - 0.019 14.7 22.6 0.039 13.7 22.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 CAR26147.1 - 0.084 12.2 20.9 0.17 11.2 20.9 1.5 1 0 0 1 1 1 0 NOA36 protein BPA_C PF18040.1 CAR26147.1 - 0.09 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 beta porphyranase A C-terminal SDA1 PF05285.12 CAR26147.1 - 1.2 8.5 21.5 1.9 7.8 21.5 1.3 1 0 0 1 1 1 0 SDA1 TFIIA PF03153.13 CAR26147.1 - 8.7 6.2 23.8 14 5.6 23.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myb_DNA-binding PF00249.31 CAR26148.1 - 1.5e-11 44.3 2.5 3.2e-10 40.0 0.1 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR26148.1 - 7.8e-09 35.7 0.8 7.8e-09 35.7 0.8 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain TatD_DNase PF01026.21 CAR26149.1 - 1.5e-36 126.1 0.0 2e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase PP2C PF00481.21 CAR26150.1 - 9.6e-81 271.2 0.0 1.5e-80 270.6 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Chorismate_bind PF00425.18 CAR26151.1 - 9.9e-89 297.3 0.0 3.7e-88 295.4 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 CAR26151.1 - 1.6e-29 102.9 0.1 2.1e-27 96.1 0.0 3.2 2 1 0 3 3 3 1 Anthranilate synthase component I, N terminal region POR PF01558.18 CAR26151.1 - 0.015 15.4 0.0 0.083 13.0 0.0 2.0 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Sel_put PF04328.13 CAR26151.1 - 0.14 12.3 0.0 7.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Selenoprotein, putative PTH2 PF01981.16 CAR26152.1 - 1.1e-42 145.0 0.0 1.6e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Myc_N PF01056.18 CAR26152.1 - 0.0033 17.4 0.8 0.004 17.1 0.8 1.1 1 0 0 1 1 1 1 Myc amino-terminal region AIF-MLS PF14962.6 CAR26152.1 - 0.017 15.1 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence ArAE_2 PF10334.9 CAR26152.1 - 0.022 14.6 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 UBA_e1_thiolCys PF10585.9 CAR26152.1 - 0.03 14.3 0.1 0.041 13.8 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site RNA_pol_3_Rpc31 PF11705.8 CAR26152.1 - 0.032 14.5 7.2 0.042 14.1 7.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 CAR26152.1 - 0.045 13.1 1.1 0.054 12.8 1.1 1.1 1 0 0 1 1 1 0 BUD22 DUF4611 PF15387.6 CAR26152.1 - 0.053 13.7 3.7 0.3 11.3 4.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 CAR26152.1 - 0.15 10.1 6.2 0.19 9.8 6.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 CAR26152.1 - 0.36 11.2 5.2 0.57 10.6 5.2 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vpu PF00558.19 CAR26152.1 - 4 7.3 6.5 8.8 6.2 6.5 1.5 1 0 0 1 1 1 0 Vpu protein SEP PF08059.13 CAR26153.1 - 5.1e-23 81.4 1.5 6.4e-22 77.9 0.2 2.6 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 CAR26153.1 - 2e-16 60.0 0.0 3.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CAR26153.1 - 5.3e-07 29.4 1.6 8.9e-07 28.6 1.6 1.4 1 0 0 1 1 1 1 UBA-like domain Meth_synt_2 PF01717.18 CAR26154.1 - 2.4e-151 503.6 0.0 3.7e-148 493.1 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CAR26154.1 - 1.2e-123 412.7 0.0 5.8e-116 387.4 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain IES5 PF17335.2 CAR26155.1 - 3.3e-46 156.2 3.4 3.6e-46 156.1 3.4 1.0 1 0 0 1 1 1 1 Ino80 complex subunit 5 APC_N_CC PF16689.5 CAR26155.1 - 0.0015 18.5 1.1 0.002 18.2 0.1 1.7 2 0 0 2 2 2 1 Coiled-coil N-terminus of APC, dimerisation domain Mei5 PF10376.9 CAR26155.1 - 0.025 14.4 2.4 0.46 10.3 0.1 2.0 1 1 1 2 2 2 0 Double-strand recombination repair protein RICTOR_N PF14664.6 CAR26156.1 - 1e-98 330.8 9.9 2.5e-98 329.5 9.9 1.7 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 CAR26156.1 - 8e-32 109.1 4.7 1.7e-29 101.6 0.2 4.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 CAR26156.1 - 8.1e-28 97.0 1.2 1.1e-26 93.3 0.6 3.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 CAR26156.1 - 4.5e-27 94.1 1.6 3.4e-26 91.3 0.9 3.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 Cnn_1N PF07989.11 CAR26156.1 - 0.11 12.7 2.8 14 5.9 0.3 3.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF1640 PF07798.11 CAR26156.1 - 0.37 10.8 6.3 1 9.4 6.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) PspA_IM30 PF04012.12 CAR26156.1 - 0.63 9.6 4.0 1.8 8.1 0.2 2.3 2 0 0 2 2 2 0 PspA/IM30 family Tup_N PF08581.10 CAR26156.1 - 0.92 9.9 8.5 2 8.8 0.5 2.9 1 1 1 2 2 2 0 Tup N-terminal DUF724 PF05266.14 CAR26156.1 - 1.3 8.8 6.9 4 7.2 6.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Macoilin PF09726.9 CAR26156.1 - 1.7 7.1 18.9 0.01 14.4 10.4 1.5 2 0 0 2 2 2 0 Macoilin family Snf7 PF03357.21 CAR26156.1 - 1.8 8.1 7.1 2.1 7.9 0.9 2.6 2 0 0 2 2 2 0 Snf7 DivIC PF04977.15 CAR26156.1 - 2.3 8.0 6.0 18 5.2 0.3 2.8 2 0 0 2 2 2 0 Septum formation initiator Tropomyosin_1 PF12718.7 CAR26156.1 - 2.7 8.1 7.7 18 5.5 7.7 2.3 1 1 0 1 1 1 0 Tropomyosin like FlxA PF14282.6 CAR26156.1 - 7.8 6.6 14.7 9.5 6.3 5.9 3.2 2 1 1 3 3 3 0 FlxA-like protein Cmc1 PF08583.10 CAR26158.1 - 3e-17 62.4 7.6 4e-17 62.0 7.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 CAR26158.1 - 0.0033 17.1 2.2 0.0056 16.4 2.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.13 CAR26158.1 - 0.021 15.0 2.4 0.56 10.4 0.3 2.4 2 0 0 2 2 2 0 CHCH domain HMG_box_2 PF09011.10 CAR26158.1 - 0.036 14.7 1.5 0.073 13.7 1.5 1.5 1 0 0 1 1 1 0 HMG-box domain DUF4606 PF15379.6 CAR26158.1 - 0.04 14.2 3.7 0.048 13.9 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) GAIN_A PF18619.1 CAR26158.1 - 0.052 13.8 0.1 0.15 12.3 0.1 1.8 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A Proteasome PF00227.26 CAR26159.1 - 2.1e-42 144.8 0.0 2.7e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sec7 PF01369.20 CAR26160.1 - 3.8e-16 59.3 0.2 7.8e-16 58.3 0.2 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 CAR26160.1 - 0.018 15.4 0.1 0.26 11.7 0.1 2.8 3 0 0 3 3 3 0 Pleckstrin homology domain Rad51 PF08423.11 CAR26161.1 - 3.1e-127 423.1 0.0 3.8e-127 422.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CAR26161.1 - 8.7e-13 48.3 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 CAR26161.1 - 8.5e-10 38.5 0.0 1.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 CAR26161.1 - 1.6e-07 31.8 0.1 3.1e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 CAR26161.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CAR26161.1 - 0.0026 17.1 0.6 0.032 13.5 0.0 2.6 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain HHH PF00633.23 CAR26161.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sel1 PF08238.12 CAR26162.1 - 1.9e-45 152.3 18.1 3.7e-08 33.8 0.6 7.6 7 0 0 7 7 7 7 Sel1 repeat DUF4261 PF14080.6 CAR26162.1 - 0.068 13.3 0.1 0.17 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) TPR_6 PF13174.6 CAR26162.1 - 7.6 7.4 7.6 54 4.7 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Kinesin PF00225.23 CAR26163.1 - 2.1e-103 345.8 11.8 1.7e-102 342.8 9.6 2.9 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CAR26163.1 - 3.4e-26 92.0 0.1 1.9e-25 89.6 0.1 2.4 1 0 0 1 1 1 1 Microtubule binding ResIII PF04851.15 CAR26163.1 - 0.14 12.1 0.0 0.14 12.1 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Baculo_PEP_C PF04513.12 CAR26163.1 - 0.27 11.3 20.0 0.17 11.9 2.8 4.4 2 2 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus AhpC-TSA PF00578.21 CAR26164.1 - 3.2e-30 104.6 0.0 5.2e-30 103.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CAR26164.1 - 4.2e-12 45.7 0.3 8.1e-12 44.8 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CAR26164.1 - 6.8e-10 38.8 0.0 1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 CAR26164.1 - 0.016 15.4 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Fungal_trans PF04082.18 CAR26165.1 - 1.3e-20 73.5 0.8 3e-20 72.4 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR26165.1 - 6.4e-09 35.8 8.7 6.4e-09 35.8 8.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UCH PF00443.29 CAR26166.1 - 1.7e-64 217.8 15.9 9.1e-64 215.4 15.9 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR26166.1 - 5e-22 78.9 8.7 3.1e-17 63.2 3.9 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pribosyltran_N PF13793.6 CAR26167.1 - 4.5e-44 149.1 0.3 4.3e-42 142.7 0.1 2.4 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CAR26167.1 - 8.3e-35 120.5 1.3 4.1e-29 101.9 0.6 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CAR26167.1 - 3e-16 59.3 0.9 1.6e-15 57.0 0.6 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAR26167.1 - 0.0018 17.8 0.1 0.003 17.0 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UQ_con PF00179.26 CAR26168.1 - 9.6e-22 77.1 0.1 1.4e-21 76.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Gag_p12 PF01141.18 CAR26168.1 - 0.23 11.8 1.7 0.35 11.2 0.1 2.0 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 ADH_zinc_N_2 PF13602.6 CAR26169.1 - 5e-14 53.5 0.0 1.1e-13 52.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR26169.1 - 0.00012 21.9 0.1 0.00024 21.0 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 CAR26169.1 - 0.025 15.0 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 CAR26169.1 - 0.067 13.2 0.0 0.21 11.6 0.0 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NOGCT PF08155.11 CAR26169.1 - 0.63 10.1 3.1 0.46 10.5 0.6 2.0 2 0 0 2 2 2 0 NOGCT (NUC087) domain zf-CSL PF05207.13 CAR26170.1 - 5.8e-20 70.8 0.9 8e-20 70.3 0.9 1.2 1 0 0 1 1 1 1 CSL zinc finger ATPase-cat_bd PF12156.8 CAR26170.1 - 0.086 13.6 0.0 0.13 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Ribosomal_S8e PF01201.22 CAR26171.1 - 8.3e-56 187.9 2.0 1e-55 187.7 2.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e AAR2 PF05282.11 CAR26172.1 - 2.1e-29 103.1 0.5 9.7e-29 100.9 0.5 1.8 1 1 0 1 1 1 1 AAR2 protein Strep_his_triad PF04270.13 CAR26172.1 - 0.13 12.3 0.1 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 Streptococcal histidine triad protein HSP70 PF00012.20 CAR26173.1 - 4.9e-256 850.7 8.8 5.6e-256 850.5 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR26173.1 - 1.4e-15 57.0 0.4 1.1e-14 54.0 0.2 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CAR26173.1 - 0.0098 16.3 3.4 10 6.6 0.1 3.6 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 CAR26173.1 - 0.031 13.6 0.5 0.1 11.8 0.0 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 CAR26173.1 - 0.034 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Zincin_2 PF10103.9 CAR26173.1 - 0.054 12.8 0.4 0.097 11.9 0.0 1.6 2 0 0 2 2 2 0 Zincin-like metallopeptidase GARP PF16731.5 CAR26173.1 - 5.9 6.5 14.0 12 5.5 0.1 2.3 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma tRNA-synt_1 PF00133.22 CAR26174.1 - 6e-243 807.5 0.3 1e-242 806.7 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CAR26174.1 - 4.1e-28 98.3 0.1 1.6e-27 96.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CAR26174.1 - 4.1e-16 58.7 1.5 1.8e-05 23.7 0.2 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CAR26174.1 - 0.00028 20.3 0.0 0.00091 18.7 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 CAR26174.1 - 0.0083 15.7 0.1 0.14 11.7 0.1 2.6 2 1 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 AAA_23 PF13476.6 CAR26175.1 - 0.0038 17.7 1.7 0.0043 17.6 1.7 1.1 1 0 0 1 1 1 1 AAA domain DUF5344 PF17279.2 CAR26175.1 - 0.006 17.1 0.3 0.014 15.9 0.3 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5344) Atg8 PF02991.16 CAR26176.1 - 1.4e-50 169.8 0.1 1.6e-50 169.6 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CAR26176.1 - 1.1e-06 29.0 0.0 1.4e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Nucleoporin_N PF08801.11 CAR26177.1 - 1.9e-137 458.6 6.2 3e-137 457.9 6.2 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CAR26177.1 - 1.8e-132 443.1 5.0 5.9e-132 441.4 5.0 1.7 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal MAM1 PF10434.9 CAR26178.1 - 1.6e-42 146.0 4.9 6.1e-42 144.1 4.1 2.1 1 1 1 2 2 2 1 Monopolin complex protein MAM1 Pox_A_type_inc PF04508.12 CAR26178.1 - 0.0048 16.7 0.1 4.3 7.4 0.1 2.6 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat GatB_N PF02934.15 CAR26179.1 - 2.1e-91 306.1 0.0 3.5e-91 305.4 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CAR26179.1 - 5.9e-30 104.1 1.3 1e-29 103.3 1.3 1.4 1 0 0 1 1 1 1 GatB domain SpoVIF PF14069.6 CAR26179.1 - 0.086 12.6 1.2 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Stage VI sporulation protein F GST_C_6 PF17171.4 CAR26179.1 - 0.12 12.2 0.1 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain EF-hand_11 PF08976.11 CAR26179.1 - 0.39 11.6 1.7 1.7 9.6 0.6 2.6 3 1 0 3 3 3 0 EF-hand domain DUF5349 PF17298.2 CAR26180.1 - 1.7e-51 176.1 52.7 1.8e-50 172.8 52.7 2.3 1 1 0 1 1 1 1 Family of unknown function (DUF5349) Menin PF05053.13 CAR26180.1 - 3.4 5.9 4.6 4.4 5.5 4.6 1.2 1 0 0 1 1 1 0 Menin WD40 PF00400.32 CAR26181.1 - 7.4e-18 64.6 7.2 8.2e-05 23.3 0.5 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR26181.1 - 3.8e-06 27.1 0.0 0.0086 16.3 0.0 4.3 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR26181.1 - 0.00013 21.9 0.0 0.18 11.7 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CAR26181.1 - 0.0094 14.6 0.1 0.62 8.6 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CAR26181.1 - 0.012 14.6 0.0 0.048 12.6 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein T4-Gluco-transf PF09198.10 CAR26181.1 - 0.18 11.4 0.1 0.37 10.4 0.1 1.5 1 0 0 1 1 1 0 Bacteriophage T4 beta-glucosyltransferase LisH PF08513.11 CAR26182.1 - 1.6e-05 24.7 0.1 2.9e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 LisH ALG3 PF05208.13 CAR26183.1 - 3.7e-126 421.3 21.0 4.5e-126 421.1 21.0 1.1 1 0 0 1 1 1 1 ALG3 protein IBN_N PF03810.19 CAR26184.1 - 3.8e-13 49.2 5.7 2.3e-10 40.3 0.8 4.4 3 0 0 3 3 3 2 Importin-beta N-terminal domain HEAT_EZ PF13513.6 CAR26184.1 - 5e-13 49.2 0.2 0.047 14.2 0.0 7.4 6 1 1 7 7 7 2 HEAT-like repeat HEAT PF02985.22 CAR26184.1 - 1.2e-08 34.5 3.1 0.28 11.5 0.0 6.6 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 CAR26184.1 - 3.1e-06 27.5 2.7 1.5 9.2 0.3 6.2 4 2 4 8 8 8 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CAR26184.1 - 0.013 16.1 5.4 78 4.0 0.0 6.1 5 1 3 8 8 8 0 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 CAR26184.1 - 0.029 13.6 0.9 7.4 5.7 0.0 3.5 3 0 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 CAR26184.1 - 0.044 13.8 7.4 2 8.5 0.1 4.9 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 G-alpha PF00503.20 CAR26184.1 - 0.079 12.1 0.1 0.17 11.0 0.1 1.6 1 0 0 1 1 1 0 G-protein alpha subunit Xpo1 PF08389.12 CAR26184.1 - 0.27 11.3 3.3 0.81 9.7 0.1 3.6 4 1 0 4 4 4 0 Exportin 1-like protein Ank_2 PF12796.7 CAR26185.1 - 8.1e-08 32.8 2.6 0.0066 17.0 0.5 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) KilA-N PF04383.13 CAR26185.1 - 1.1e-05 25.2 0.4 5.2e-05 23.1 0.4 2.2 1 1 0 1 1 1 1 KilA-N domain Ank_3 PF13606.6 CAR26185.1 - 0.00012 22.3 2.2 0.13 12.9 0.1 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CAR26185.1 - 0.00019 22.0 4.8 0.056 14.0 1.2 3.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CAR26185.1 - 0.00069 19.9 6.9 0.23 12.0 0.5 3.7 4 0 0 4 4 4 2 Ankyrin repeat TMEM247 PF15444.6 CAR26185.1 - 0.027 14.5 0.5 0.062 13.3 0.5 1.6 1 0 0 1 1 1 0 Transmembrane protein 247 Ank_5 PF13857.6 CAR26185.1 - 0.072 13.4 5.7 0.6 10.5 0.7 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Type2_restr_D3 PF16902.5 CAR26185.1 - 0.58 10.1 2.3 4 7.4 1.1 2.5 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain Latarcin PF10279.9 CAR26185.1 - 1.1 9.7 8.9 1.3 9.5 0.3 3.8 3 1 1 4 4 4 0 Latarcin precursor PBP1_TM PF14812.6 CAR26185.1 - 3.3 8.1 13.1 1.2 9.5 4.9 3.1 3 0 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 CAR26185.1 - 6.5 6.0 7.0 19 4.4 7.0 1.7 1 0 0 1 1 1 0 NOA36 protein LSM PF01423.22 CAR26186.1 - 1.8e-15 56.4 0.3 2.6e-15 55.9 0.3 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAR26186.1 - 6e-05 23.1 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain MyTH4 PF00784.17 CAR26186.1 - 0.12 12.9 0.1 0.28 11.7 0.1 1.6 1 0 0 1 1 1 0 MyTH4 domain EMP70 PF02990.16 CAR26187.1 - 3.7e-131 438.3 14.1 3.7e-131 438.3 14.1 1.7 2 0 0 2 2 2 1 Endomembrane protein 70 MFS_1 PF07690.16 CAR26187.1 - 0.31 9.9 29.9 0.043 12.7 8.6 2.3 1 1 1 2 2 2 0 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.20 CAR26187.1 - 4.5 6.8 13.4 0.03 13.9 0.7 2.9 3 1 0 3 3 3 0 Prokaryotic cytochrome b561 TPR_2 PF07719.17 CAR26188.1 - 4.7e-39 129.3 9.1 3e-08 33.2 0.6 8.7 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_1 PF00515.28 CAR26188.1 - 4e-38 127.7 10.0 7.3e-10 38.2 0.9 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 CAR26188.1 - 1.1e-32 109.4 11.3 1.5e-06 28.0 0.0 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR26188.1 - 1.1e-26 92.9 23.1 7.8e-19 67.7 2.2 4.4 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CAR26188.1 - 2.7e-21 75.6 6.9 0.00023 21.4 0.0 7.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 CAR26188.1 - 4.1e-20 71.2 6.7 0.006 16.2 0.0 7.9 4 3 4 8 8 8 4 TPR repeat TPR_16 PF13432.6 CAR26188.1 - 1.1e-19 70.8 0.0 3.6e-07 30.7 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CAR26188.1 - 1.4e-17 62.3 9.6 5.6e-06 26.0 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAR26188.1 - 3.5e-17 61.5 10.6 4.9e-05 23.4 0.4 7.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAR26188.1 - 8.5e-14 51.1 3.5 0.016 16.0 0.0 7.0 4 2 3 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CAR26188.1 - 3.3e-13 49.9 7.9 9.3e-05 22.9 0.0 6.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 CAR26188.1 - 5.5e-10 39.2 0.2 0.0042 17.2 0.2 4.4 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_6 PF13174.6 CAR26188.1 - 8e-09 35.6 10.1 0.0042 17.6 0.1 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 CAR26188.1 - 6.6e-07 28.8 0.0 0.017 14.4 0.0 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 CAR26188.1 - 3.3e-05 23.6 5.9 0.037 13.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR PF01535.20 CAR26188.1 - 0.00076 19.6 0.4 3.6 8.0 0.4 3.3 3 0 0 3 3 2 2 PPR repeat SUIM_assoc PF16619.5 CAR26188.1 - 0.0024 17.9 4.3 0.0082 16.2 2.1 3.0 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 TPR_20 PF14561.6 CAR26188.1 - 0.0029 17.9 3.5 7.4 7.0 0.0 4.5 5 0 0 5 5 3 0 Tetratricopeptide repeat ChAPs PF09295.10 CAR26188.1 - 0.0095 15.0 0.1 0.38 9.7 0.0 2.9 2 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) SRP_TPR_like PF17004.5 CAR26188.1 - 0.01 15.8 6.0 0.027 14.5 2.5 3.2 2 1 0 2 2 2 0 Putative TPR-like repeat TFIIA PF03153.13 CAR26188.1 - 0.011 15.7 6.3 0.018 15.0 6.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sel1 PF08238.12 CAR26188.1 - 0.024 15.3 10.5 1 10.2 0.0 4.4 3 1 0 3 3 3 0 Sel1 repeat DUF3856 PF12968.7 CAR26188.1 - 0.027 14.5 0.7 2 8.5 0.1 3.6 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) SWI-SNF_Ssr4 PF08549.10 CAR26188.1 - 0.31 9.6 9.7 0.45 9.1 9.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Fis1_TPR_C PF14853.6 CAR26188.1 - 1.3 9.2 8.3 1.3 9.1 0.2 4.5 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat SR-25 PF10500.9 CAR26188.1 - 5.5 6.5 15.4 0.19 11.3 9.4 1.5 2 0 0 2 2 1 0 Nuclear RNA-splicing-associated protein PH PF00169.29 CAR26189.1 - 2.8e-18 66.3 0.0 7.4e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.28 CAR26189.1 - 5.6e-14 51.5 0.1 1.1e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 CAR26189.1 - 5.1e-10 39.3 0.0 1.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 CAR26189.1 - 1.2e-09 37.9 0.1 2.4e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.6 CAR26189.1 - 8.6e-05 22.7 0.0 0.008 16.4 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.17 CAR26189.1 - 0.00032 20.3 0.0 0.00099 18.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 CAR26189.1 - 0.00033 21.0 0.0 0.00059 20.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 CAR26189.1 - 0.00069 20.0 0.0 0.0033 17.8 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain BORCS8 PF10167.9 CAR26189.1 - 0.046 13.7 1.1 0.24 11.4 0.1 2.3 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 NT-C2 PF10358.9 CAR26191.1 - 1.7e-51 173.7 0.7 8.7e-51 171.5 1.5 1.7 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins zf-C3HC4 PF00097.25 CAR26193.1 - 4.7e-10 39.2 8.0 8.4e-10 38.4 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAR26193.1 - 2.6e-09 36.8 7.2 4e-09 36.2 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR26193.1 - 2.2e-08 33.9 8.7 3.5e-08 33.3 8.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CAR26193.1 - 1.1e-07 31.7 8.0 2e-07 30.9 8.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CAR26193.1 - 2e-07 31.2 9.1 3.2e-07 30.6 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CAR26193.1 - 4.1e-06 26.6 7.2 8.7e-06 25.5 7.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CAR26193.1 - 2.5e-05 24.0 7.9 8.2e-05 22.4 8.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CAR26193.1 - 0.00066 19.8 8.2 0.0012 18.9 8.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CAR26193.1 - 0.0015 18.6 3.1 0.0022 18.0 3.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CAR26193.1 - 0.025 14.4 5.2 0.083 12.7 5.2 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CAR26193.1 - 0.066 13.5 6.4 0.26 11.6 6.5 1.9 1 1 1 2 2 2 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CAR26193.1 - 0.073 12.8 8.0 0.33 10.8 4.7 2.6 2 1 0 2 2 2 0 RING-like zinc finger FYVE PF01363.21 CAR26193.1 - 0.19 11.9 5.5 0.58 10.3 3.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger DUF2992 PF11208.8 CAR26193.1 - 0.21 11.9 2.3 0.2 11.9 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2992) T-box_assoc PF16176.5 CAR26193.1 - 0.21 11.6 0.8 0.33 11.0 0.8 1.3 1 0 0 1 1 1 0 T-box transcription factor-associated Ribosomal_L14 PF00238.19 CAR26194.1 - 5e-33 113.8 0.0 6e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PI3_PI4_kinase PF00454.27 CAR26195.1 - 1.1e-55 189.2 0.0 3.1e-55 187.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 CAR26195.1 - 5.8e-24 84.9 2.3 3.9e-23 82.3 2.3 2.6 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 CAR26195.1 - 7.7e-13 48.0 0.1 2.1e-12 46.6 0.1 1.8 1 0 0 1 1 1 1 FATC domain SH3_9 PF14604.6 CAR26196.1 - 1.1e-10 41.1 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CAR26196.1 - 1.3e-10 40.7 0.1 2.4e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CAR26196.1 - 1.7e-07 30.8 0.0 3.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TctB PF07331.11 CAR26196.1 - 0.072 13.4 3.6 0.11 12.8 3.6 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Phage_tail_2 PF06199.11 CAR26196.1 - 0.094 12.8 0.3 0.18 11.9 0.3 1.4 1 0 0 1 1 1 0 Phage tail tube protein SH3_10 PF17902.1 CAR26196.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Aa_trans PF01490.18 CAR26197.1 - 8.8e-102 340.9 21.3 1e-101 340.7 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CAR26197.1 - 1.2e-09 37.7 10.9 1.2e-09 37.7 10.9 1.7 3 0 0 3 3 3 1 Tryptophan/tyrosine permease family Ribosomal_S21 PF01165.20 CAR26198.1 - 1.5e-11 43.8 0.1 2.8e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Peptidase_M24 PF00557.24 CAR26199.1 - 1.3e-47 162.2 0.0 1.8e-47 161.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Motile_Sperm PF00635.26 CAR26200.1 - 8e-25 86.8 0.0 1.3e-24 86.1 0.0 1.4 1 1 0 1 1 1 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CAR26200.1 - 0.0048 17.1 0.1 0.0079 16.4 0.1 1.3 1 0 0 1 1 1 1 Transmembrane protein 131-like Ribosomal_L32e PF01655.18 CAR26201.1 - 4.2e-45 152.6 1.2 4.9e-45 152.4 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Asn_synthase PF00733.21 CAR26202.1 - 3.6e-92 309.8 0.2 1.2e-53 183.0 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CAR26202.1 - 6.5e-34 116.5 0.0 1.1e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CAR26202.1 - 1.7e-27 96.3 0.0 3.7e-27 95.1 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CAR26202.1 - 9.1e-05 22.0 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 CAR26202.1 - 0.035 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase CBF PF03914.17 CAR26203.1 - 1.7e-34 119.3 0.5 3.5e-34 118.3 0.2 1.7 2 0 0 2 2 2 1 CBF/Mak21 family Metallophos PF00149.28 CAR26204.1 - 1.4e-31 110.6 0.1 2.3e-31 109.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CAR26204.1 - 3.9e-23 81.5 0.2 1.8e-22 79.4 0.0 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 CAR26204.1 - 1.6e-14 53.0 3.9 1.5e-05 24.6 0.1 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR26204.1 - 8.1e-14 50.6 0.4 0.0016 18.4 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAR26204.1 - 3.8e-09 36.1 0.7 0.0005 19.7 0.0 3.5 4 0 0 4 4 4 2 TPR repeat TPR_17 PF13431.6 CAR26204.1 - 1.7e-05 24.8 0.6 0.33 11.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAR26204.1 - 2e-05 24.5 3.2 3.5 8.1 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 CAR26204.1 - 4.1e-05 23.6 0.0 9.6e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAR26204.1 - 0.0067 16.7 0.5 0.71 10.2 0.2 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAR26204.1 - 0.016 15.2 0.1 1.1 9.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAR26204.1 - 0.024 15.3 0.0 4.1 8.1 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR26204.1 - 0.031 14.3 0.3 1.5 8.9 0.1 2.7 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 CAR26204.1 - 0.061 12.5 0.2 0.13 11.5 0.2 1.5 1 1 0 1 1 1 0 Tetratricopeptide repeat Sel1 PF08238.12 CAR26204.1 - 0.11 13.2 0.1 0.34 11.6 0.1 1.9 1 0 0 1 1 1 0 Sel1 repeat Rrp15p PF07890.12 CAR26205.1 - 1e-28 100.3 11.2 1e-28 100.3 11.2 2.4 2 1 0 2 2 2 1 Rrp15p Ndc1_Nup PF09531.10 CAR26205.1 - 8.8 4.9 6.1 10 4.7 6.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Kinesin PF00225.23 CAR26206.1 - 1.4e-103 346.4 4.1 1.4e-103 346.4 4.1 2.7 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CAR26206.1 - 1e-56 191.0 0.5 1e-56 191.0 0.5 3.2 4 0 0 4 4 4 1 Microtubule binding HrpB7 PF09486.10 CAR26206.1 - 0.00082 19.8 3.6 0.00082 19.8 3.6 2.8 2 1 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) DUF1664 PF07889.12 CAR26206.1 - 0.0036 17.3 6.8 0.0036 17.3 6.8 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Calpain_inhib PF00748.19 CAR26206.1 - 0.21 12.1 2.3 0.42 11.1 0.6 2.1 2 0 0 2 2 2 0 Calpain inhibitor DegT_DnrJ_EryC1 PF01041.17 CAR26206.1 - 0.6 9.3 7.9 0.044 13.1 1.6 2.2 2 1 1 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family Bap31_Bap29_C PF18035.1 CAR26206.1 - 0.91 9.6 7.0 1.1 9.4 2.2 3.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF725 PF05267.12 CAR26206.1 - 3 7.9 14.5 0.027 14.4 1.8 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF725) Filament PF00038.21 CAR26206.1 - 6.6 6.2 44.8 0.02 14.5 9.1 3.3 2 1 1 3 3 3 0 Intermediate filament protein Acyltransferase PF01553.21 CAR26207.1 - 2e-14 53.3 0.0 4.6e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 CAR26208.1 - 0.14 11.8 0.0 0.46 10.1 0.0 1.8 1 1 0 1 1 1 0 Acyltransferase DUF5355 PF17306.2 CAR26209.1 - 1.8e-110 369.1 0.3 2.2e-110 368.8 0.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5355) Ammonium_transp PF00909.21 CAR26210.1 - 2.8e-117 391.8 24.7 3.3e-117 391.6 24.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 CAR26210.1 - 0.2 11.7 0.1 0.2 11.7 0.1 3.9 4 0 0 4 4 4 0 Bacteriophage P21 holin S ABC2_membrane_2 PF12679.7 CAR26210.1 - 0.38 10.0 8.2 0.027 13.7 2.9 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein WD40 PF00400.32 CAR26211.1 - 7.3e-16 58.3 4.0 6.3e-05 23.7 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR26211.1 - 0.0059 16.9 0.0 0.5 10.7 0.0 2.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 CAR26212.1 - 1.6e-85 287.0 0.0 5.4e-85 285.3 0.0 1.9 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 CAR26212.1 - 3.3e-06 27.3 0.2 0.42 10.9 0.0 4.7 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAR26212.1 - 3.1e-05 23.4 0.2 0.034 13.5 0.0 3.1 2 1 0 3 3 3 2 WD40-like domain RAB3GAP2_N PF14655.6 CAR26212.1 - 0.046 13.0 0.0 0.098 11.9 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Cathelicidins PF00666.17 CAR26212.1 - 0.057 13.7 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 Cathelicidin Ge1_WD40 PF16529.5 CAR26212.1 - 0.078 11.9 0.0 5 6.0 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DNA_pol_alpha_N PF12254.8 CAR26212.1 - 0.17 12.0 4.6 0.43 10.7 4.6 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal COG2 PF06148.11 CAR26213.1 - 5.5e-08 33.0 3.1 1.1e-07 32.1 2.2 1.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 LOH1CR12 PF10158.9 CAR26213.1 - 0.035 14.1 1.2 0.046 13.7 0.4 1.7 2 0 0 2 2 2 0 Tumour suppressor protein PilJ PF13675.6 CAR26213.1 - 0.04 13.9 0.5 5.1 7.1 0.6 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Syntaxin_2 PF14523.6 CAR26213.1 - 0.098 13.0 8.6 1.7 9.1 5.4 2.8 3 0 0 3 3 3 0 Syntaxin-like protein DUF2730 PF10805.8 CAR26213.1 - 0.81 9.8 4.3 0.48 10.6 1.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Nup54 PF13874.6 CAR26214.1 - 2.5e-36 124.9 3.4 2.5e-36 124.9 3.4 2.9 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 CAR26214.1 - 4.8e-09 37.0 122.2 1.3e-08 35.6 30.0 4.4 1 1 2 3 3 3 2 Nucleoporin FG repeat region Fib_alpha PF08702.10 CAR26214.1 - 0.033 14.4 0.7 0.033 14.4 0.7 3.1 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family eIF-3_zeta PF05091.12 CAR26214.1 - 0.5 9.3 21.5 0.84 8.5 21.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 CAR26214.1 - 2.7 6.7 14.4 3.8 6.2 14.4 1.4 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CAR26214.1 - 7.4 5.1 19.3 9.9 4.7 19.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tom5 PF10642.9 CAR26216.1 - 1e-19 70.3 0.1 1.1e-19 70.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.11 CAR26217.1 - 5.2e-12 45.6 0.0 1.4e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SRP54 PF00448.22 CAR26217.1 - 0.26 10.9 2.1 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain THOC7 PF05615.13 CAR26217.1 - 3.4 7.9 15.2 0.092 13.0 7.2 2.5 3 0 0 3 3 3 0 Tho complex subunit 7 DUF4083 PF13314.6 CAR26217.1 - 4.1 7.4 6.9 0.62 10.0 0.9 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4083) Ribosom_S12_S23 PF00164.25 CAR26218.1 - 4.1e-51 171.4 0.3 5.3e-51 171.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 LisH PF08513.11 CAR26220.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 LisH Acetyltransf_1 PF00583.25 CAR26221.1 - 5.7e-10 39.5 0.0 7.7e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CAR26221.1 - 2.1e-06 27.6 0.0 3.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CAR26221.1 - 1.4e-05 25.0 0.0 2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR26221.1 - 1.5e-05 25.3 0.0 2.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CAR26221.1 - 0.012 15.8 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CAR26221.1 - 0.043 13.9 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LSM14 PF12701.7 CAR26222.1 - 1.2e-22 79.7 0.0 1.2e-22 79.7 0.0 1.6 2 0 0 2 2 2 1 Scd6-like Sm domain TFIIA PF03153.13 CAR26222.1 - 0.00013 22.1 16.6 0.00016 21.8 16.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BLOC1S3 PF15753.5 CAR26222.1 - 0.08 13.1 2.9 0.13 12.4 2.9 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 SM-ATX PF14438.6 CAR26222.1 - 0.083 13.0 1.1 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 Ataxin 2 SM domain FDF PF09532.10 CAR26222.1 - 0.34 11.8 16.4 0.33 11.8 0.4 3.5 2 1 1 3 3 3 0 FDF domain DUF2868 PF11067.8 CAR26222.1 - 0.57 9.6 5.6 0.83 9.1 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Dicty_REP PF05086.12 CAR26222.1 - 3.2 5.6 5.3 3.8 5.4 5.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GRP PF07172.11 CAR26222.1 - 3.3 8.4 15.8 0.19 12.4 9.6 2.0 2 0 0 2 2 2 0 Glycine rich protein family RP-C_C PF11800.8 CAR26223.1 - 8.1 6.5 8.6 23 5.0 5.1 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region DDHD PF02862.17 CAR26224.1 - 8e-39 134.1 0.0 1.2e-24 87.8 0.1 2.5 1 1 1 2 2 2 2 DDHD domain LCAT PF02450.15 CAR26224.1 - 0.00038 19.8 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Palm_thioest PF02089.15 CAR26224.1 - 0.03 14.2 0.0 0.076 12.8 0.0 1.7 2 0 0 2 2 2 0 Palmitoyl protein thioesterase WWE PF02825.20 CAR26224.1 - 0.042 14.4 0.6 0.25 12.0 0.3 2.5 2 1 0 2 2 2 0 WWE domain Abhydrolase_6 PF12697.7 CAR26224.1 - 0.11 13.1 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 CAR26224.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 CAR26224.1 - 0.13 11.5 0.0 2 7.7 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF21 PF01595.20 CAR26225.1 - 6.3e-31 107.4 1.4 1.1e-30 106.7 0.5 1.8 3 0 0 3 3 3 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CAR26225.1 - 0.00018 21.9 0.0 0.23 11.9 0.0 2.7 2 0 0 2 2 2 2 CBS domain Pkinase PF00069.25 CAR26226.1 - 1.6e-49 168.7 0.0 3.3e-49 167.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR26226.1 - 4.4e-22 78.6 0.0 7.3e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR26226.1 - 0.008 15.5 0.1 0.035 13.4 0.0 2.1 3 0 0 3 3 3 1 Kinase-like Pribosyl_synth PF14572.6 CAR26227.1 - 2.2e-44 151.7 0.3 3.9e-44 150.9 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CAR26227.1 - 2.4e-36 124.2 0.1 7.2e-36 122.7 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CAR26227.1 - 2.4e-12 46.6 1.5 5.7e-12 45.4 0.3 2.2 2 1 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAR26227.1 - 0.041 13.3 0.1 0.073 12.5 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Adap_comp_sub PF00928.21 CAR26228.1 - 2.3e-77 259.9 0.2 3e-77 259.6 0.2 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF5484 PF17583.2 CAR26228.1 - 0.68 9.6 2.6 2.7 7.7 0.0 3.1 4 0 0 4 4 4 0 Family of unknown function (DUF5484) TatC PF00902.18 CAR26229.1 - 0.019 14.8 1.1 0.032 14.0 1.1 1.3 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Halogen_Hydrol PF10112.9 CAR26229.1 - 0.06 13.4 0.7 0.1 12.6 0.7 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Prominin PF05478.11 CAR26229.1 - 0.46 8.4 1.4 0.62 7.9 1.4 1.1 1 0 0 1 1 1 0 Prominin CRT10 PF08728.10 CAR26230.1 - 1.2e-156 522.9 0.0 1.8e-156 522.3 0.0 1.3 1 1 0 1 1 1 1 CRT10 Pkinase PF00069.25 CAR26231.1 - 1.6e-51 175.2 0.0 3.2e-51 174.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR26231.1 - 3e-22 79.2 0.0 1.3e-21 77.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CAR26231.1 - 6.6e-05 22.6 0.1 0.1 12.2 0.0 2.6 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CAR26231.1 - 0.00026 20.4 0.0 0.0069 15.7 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CAR26231.1 - 0.0032 17.4 0.0 2.1 8.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 CAR26231.1 - 0.042 13.4 0.2 0.11 12.0 0.1 1.7 1 1 0 1 1 1 0 RIO1 family Actin PF00022.19 CAR26232.1 - 2.8e-109 365.4 0.0 9.1e-109 363.7 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CAR26232.1 - 0.0067 15.3 0.0 0.039 12.8 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein DUF3449 PF11931.8 CAR26233.1 - 1.6e-65 220.3 0.2 1.6e-65 220.3 0.2 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) PRP9_N PF16958.5 CAR26233.1 - 2.1e-54 183.6 3.3 2.1e-54 183.6 3.3 2.0 2 0 0 2 2 2 1 Pre-mRNA-splicing factor PRP9 N-terminus SF3A3 PF16837.5 CAR26233.1 - 6.2e-17 61.9 1.8 6.2e-17 61.9 1.8 2.6 3 1 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 CAR26233.1 - 9.4e-09 35.3 0.9 4.1e-08 33.3 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAR26233.1 - 2.1e-07 31.1 3.0 2.3e-05 24.6 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CAR26233.1 - 0.00042 20.6 0.9 0.017 15.4 0.2 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CAR26233.1 - 0.0012 19.5 3.4 0.29 12.1 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Actin_micro PF17003.5 CAR26233.1 - 0.0013 18.0 0.2 0.0013 18.0 0.2 2.3 3 0 0 3 3 3 1 Putative actin-like family Gon7 PF08738.10 CAR26233.1 - 0.022 14.9 0.2 0.091 12.8 0.2 2.1 1 0 0 1 1 1 0 Gon7 family DUF2175 PF09943.9 CAR26233.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.8 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2H2_3rep PF18868.1 CAR26233.1 - 0.15 12.8 0.3 4.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 CAR26233.1 - 0.38 11.3 6.6 4.1 8.0 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-DBF PF07535.12 CAR26233.1 - 0.88 9.7 4.2 2.3 8.4 0.2 2.6 2 0 0 2 2 2 0 DBF zinc finger DEAD PF00270.29 CAR26234.1 - 6.4e-51 172.6 0.0 1e-48 165.4 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR26234.1 - 1.4e-23 83.3 0.5 1.4e-22 80.2 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CAR26234.1 - 2e-18 66.4 6.1 2e-18 66.4 6.1 3.1 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ResIII PF04851.15 CAR26234.1 - 1.2e-06 28.7 1.5 3e-06 27.3 0.0 2.5 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit T4-Gluco-transf PF09198.10 CAR26234.1 - 0.13 11.9 0.1 0.33 10.6 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage T4 beta-glucosyltransferase tRNA_Me_trans PF03054.16 CAR26235.1 - 3.3e-114 381.4 0.0 3.8e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 CAR26235.1 - 0.015 15.0 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.17 CAR26235.1 - 0.094 11.8 0.0 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 NAD synthase Inositol_P PF00459.25 CAR26236.1 - 4.6e-56 190.3 0.1 1.4e-55 188.8 0.1 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family Git3 PF11710.8 CAR26237.1 - 1.5e-74 250.1 10.8 2.5e-74 249.4 10.8 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 CAR26237.1 - 1.3e-33 114.8 5.5 1.3e-33 114.8 5.5 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3545 PF12065.8 CAR26237.1 - 0.031 14.3 0.5 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) Exo_endo_phos PF03372.23 CAR26238.1 - 4.4e-08 32.9 0.0 1.4e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Inv-AAD PF18785.1 CAR26239.1 - 4.2e-40 136.6 0.0 7.7e-40 135.7 0.0 1.5 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase PseudoU_synth_2 PF00849.22 CAR26239.1 - 2.2e-32 112.4 0.8 3.6e-32 111.7 0.0 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.23 CAR26239.1 - 5.9e-20 71.0 0.1 1.8e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CAR26239.1 - 3.6e-07 30.0 0.0 7.4e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 MafB19-like deaminase NARP1 PF12569.8 CAR26240.1 - 2.2e-108 363.4 20.9 5.7e-79 266.4 2.4 3.9 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CAR26240.1 - 5.3e-17 60.5 11.5 0.017 15.2 0.0 9.0 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 CAR26240.1 - 1.9e-12 46.4 12.6 0.14 12.0 0.0 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CAR26240.1 - 1.3e-10 41.8 0.6 0.009 16.6 0.0 5.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAR26240.1 - 2.5e-10 39.8 8.2 0.17 12.2 0.1 7.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAR26240.1 - 4.1e-10 39.6 0.4 1.4 9.9 0.0 7.8 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAR26240.1 - 5e-08 33.1 9.8 0.075 13.3 0.1 7.7 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CAR26240.1 - 9.9e-08 32.4 4.7 0.028 14.9 0.0 6.5 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAR26240.1 - 1.3e-06 28.4 3.2 0.015 15.7 0.0 6.1 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR26240.1 - 3.2e-06 27.3 13.3 0.015 15.5 0.1 5.0 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CAR26240.1 - 9.7e-06 25.3 3.0 11 6.3 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAR26240.1 - 3.1e-05 23.7 0.1 1.5 8.8 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR26240.1 - 0.00026 21.0 6.6 0.29 11.2 0.2 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 CAR26240.1 - 0.0029 17.3 3.8 12 5.7 0.1 5.3 6 0 0 6 6 6 0 TPR repeat TPR_MalT PF17874.1 CAR26240.1 - 0.0037 16.7 0.2 0.014 14.8 0.0 2.1 2 0 0 2 2 2 1 MalT-like TPR region HetR_C PF18460.1 CAR26240.1 - 0.16 11.9 1.3 36 4.4 0.1 4.4 5 0 0 5 5 5 0 Heterocyst differentiation regulator C-terminal Hood domain TPR_6 PF13174.6 CAR26240.1 - 0.31 11.8 5.6 8.4 7.3 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat HLH PF00010.26 CAR26241.1 - 5.6e-16 58.2 0.1 9.6e-16 57.5 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SIR2 PF02146.17 CAR26242.1 - 4.1e-66 222.3 0.0 6.3e-66 221.7 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 CAR26242.1 - 1.1e-62 210.4 0.4 1.7e-62 209.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 CAR26242.1 - 0.0006 19.6 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain SF3A2 PF16835.5 CAR26243.1 - 4.5e-23 81.4 0.1 7.9e-23 80.7 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CAR26243.1 - 3.3e-05 24.1 1.1 7.1e-05 23.1 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Nuf2 PF03800.14 CAR26244.1 - 2e-43 147.9 0.9 2e-43 147.9 0.9 2.8 2 1 1 3 3 3 1 Nuf2 family Spc7 PF08317.11 CAR26244.1 - 0.0048 15.8 23.2 0.0048 15.8 23.2 2.6 1 1 1 2 2 2 1 Spc7 kinetochore protein Rep_fac-A_C PF08646.10 CAR26244.1 - 0.27 11.0 0.0 0.27 11.0 0.0 3.1 2 1 1 3 3 3 0 Replication factor-A C terminal domain CENP-F_leu_zip PF10473.9 CAR26244.1 - 0.88 9.6 45.0 0.021 14.9 10.2 3.6 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 XhlA PF10779.9 CAR26244.1 - 1.1 9.6 16.4 8.2 6.7 0.5 4.1 4 0 0 4 4 4 0 Haemolysin XhlA Mga PF05043.13 CAR26244.1 - 1.9 9.1 12.4 0.6 10.7 3.7 3.2 1 1 2 3 3 3 0 Mga helix-turn-helix domain FlaC_arch PF05377.11 CAR26244.1 - 8 6.9 27.7 6.3 7.3 0.4 5.9 3 2 0 4 4 4 0 Flagella accessory protein C (FlaC) FMO-like PF00743.19 CAR26245.1 - 5.8e-15 54.7 6.4 7.3e-06 24.7 0.8 3.3 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CAR26245.1 - 5.7e-05 22.5 0.0 0.0016 17.7 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR26245.1 - 0.00019 20.8 0.0 0.37 10.0 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAR26245.1 - 0.0032 17.5 0.0 0.24 11.4 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CAR26245.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CAR26245.1 - 0.27 10.8 0.1 0.88 9.1 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF5590 PF17881.1 CAR26246.1 - 0.24 11.5 0.9 0.41 10.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5590) RNA_pol_Rpb2_6 PF00562.28 CAR26247.1 - 0.17 10.9 2.8 0.24 10.4 2.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 PAPS_reduct PF01507.19 CAR26248.1 - 5.4e-30 104.7 0.0 3e-29 102.3 0.0 1.9 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CHCH PF06747.13 CAR26249.1 - 7.8e-05 22.7 0.5 0.0001 22.3 0.5 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 CAR26249.1 - 0.017 15.2 0.8 0.019 15.0 0.8 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Sdh5 PF03937.16 CAR26250.1 - 1.6e-27 95.3 0.4 2.3e-27 94.8 0.4 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase E1_DerP2_DerF2 PF02221.15 CAR26251.1 - 1.8e-28 99.6 0.0 2.1e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 ML domain DUF4625 PF15418.6 CAR26251.1 - 0.091 13.0 0.1 0.17 12.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) Metallophos PF00149.28 CAR26252.1 - 2.4e-38 132.7 0.1 3.1e-38 132.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAR26252.1 - 0.00055 20.3 0.5 0.0012 19.2 0.5 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 CAR26252.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 CAR26252.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) PCI PF01399.27 CAR26253.1 - 1.3e-13 51.4 0.1 2.7e-12 47.1 0.0 2.5 2 0 0 2 2 2 1 PCI domain Smg4_UPF3 PF03467.15 CAR26254.1 - 1.2e-25 90.6 12.2 1.2e-25 90.6 12.2 3.2 3 1 0 3 3 3 1 Smg-4/UPF3 family DUF1965 PF09248.10 CAR26254.1 - 0.1 12.4 0.3 0.39 10.5 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) Mpv17_PMP22 PF04117.12 CAR26255.1 - 0.057 13.6 0.2 0.2 11.9 0.1 1.9 2 0 0 2 2 2 0 Mpv17 / PMP22 family LSM PF01423.22 CAR26256.1 - 5.3e-22 77.3 0.1 1e-21 76.4 0.1 1.5 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAR26256.1 - 0.00063 19.8 0.0 0.001 19.2 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain BLACT_WH PF17778.1 CAR26256.1 - 0.29 11.1 1.6 6.4 6.8 0.2 2.2 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain PRP38 PF03371.15 CAR26257.1 - 8.7e-48 162.5 0.8 1e-47 162.2 0.8 1.0 1 0 0 1 1 1 1 PRP38 family Radial_spoke PF04712.12 CAR26257.1 - 0.06 12.3 1.2 0.077 11.9 1.2 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein ANAPC15 PF15243.6 CAR26257.1 - 0.17 12.3 10.9 0.33 11.4 10.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 NOA36 PF06524.12 CAR26257.1 - 3.5 6.8 14.5 4.7 6.4 14.5 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 CAR26257.1 - 3.9 7.2 11.5 4.8 6.8 11.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mitoc_mL59 PF18126.1 CAR26258.1 - 7.3e-30 103.9 1.4 7.3e-30 103.9 1.4 1.9 1 1 1 2 2 2 2 Mitochondrial ribosomal protein mL59 Prefoldin PF02996.17 CAR26261.1 - 3.7e-32 110.8 0.2 5e-32 110.3 0.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit SNAD4 PF18750.1 CAR26261.1 - 0.029 14.5 0.1 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 ABC_tran PF00005.27 CAR26262.1 - 4.9e-54 182.5 0.8 4.8e-26 91.9 0.1 2.9 3 0 0 3 3 3 2 ABC transporter ABC2_membrane PF01061.24 CAR26262.1 - 1.1e-41 142.6 30.9 1.1e-26 93.5 12.4 2.5 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 CAR26262.1 - 2.8e-12 47.1 12.0 0.0002 21.3 0.1 4.5 2 2 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR26262.1 - 4e-10 39.5 3.6 5.7e-06 25.9 0.2 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CAR26262.1 - 3e-09 37.0 3.8 0.00016 21.6 0.3 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CAR26262.1 - 5.9e-07 30.0 0.1 0.036 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CAR26262.1 - 2.2e-06 27.3 2.0 0.061 13.1 0.1 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 CAR26262.1 - 5.3e-06 26.2 0.4 0.00098 18.7 0.0 3.4 4 0 0 4 4 4 1 AAA domain NACHT PF05729.12 CAR26262.1 - 2.4e-05 24.3 0.0 0.016 15.2 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_23 PF13476.6 CAR26262.1 - 4.1e-05 24.2 0.3 0.054 14.0 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAR26262.1 - 9.6e-05 22.7 0.1 0.46 10.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 CAR26262.1 - 0.00011 22.8 0.8 0.68 10.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain T2SSE PF00437.20 CAR26262.1 - 0.00023 20.3 0.1 0.039 13.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.6 CAR26262.1 - 0.00053 20.3 0.0 0.098 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CAR26262.1 - 0.00096 19.5 0.3 0.43 11.0 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 CAR26262.1 - 0.0013 18.5 0.2 0.44 10.2 0.1 2.6 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 CAR26262.1 - 0.0037 17.3 4.6 0.52 10.4 0.6 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_24 PF13479.6 CAR26262.1 - 0.0048 16.6 0.0 2.2 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CAR26262.1 - 0.0048 17.3 0.1 27 5.2 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CAR26262.1 - 0.0053 16.0 0.5 1.2 8.3 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 CAR26262.1 - 0.006 16.5 0.2 4.2 7.3 0.1 2.8 3 0 0 3 3 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 CAR26262.1 - 0.0065 16.4 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CAR26262.1 - 0.0068 16.8 0.0 0.16 12.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 CAR26262.1 - 0.0088 16.2 0.0 7.2 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CAR26262.1 - 0.014 15.0 1.3 1.1 8.9 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 CAR26262.1 - 0.015 14.5 1.0 4.4 6.4 0.0 2.5 3 0 0 3 3 2 0 KAP family P-loop domain Cytidylate_kin PF02224.18 CAR26262.1 - 0.02 14.7 0.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_17 PF13207.6 CAR26262.1 - 0.027 14.9 0.2 6.3 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CAR26262.1 - 0.033 13.9 0.0 10 5.7 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain DUF2791 PF10923.8 CAR26262.1 - 0.034 13.0 0.1 2.8 6.7 0.0 2.8 2 1 1 3 3 3 0 P-loop Domain of unknown function (DUF2791) AAA_14 PF13173.6 CAR26262.1 - 0.036 14.1 0.0 6.9 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 CAR26262.1 - 0.043 13.7 0.0 1.5 8.7 0.0 2.9 3 0 0 3 3 3 0 NTPase ABC2_membrane_3 PF12698.7 CAR26262.1 - 0.044 12.9 26.8 0.18 10.9 12.5 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein FtsK_SpoIIIE PF01580.18 CAR26262.1 - 0.054 12.9 1.5 0.67 9.3 0.4 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.18 CAR26262.1 - 0.072 12.8 0.5 6.9 6.3 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Pox_A32 PF04665.12 CAR26262.1 - 0.11 11.9 2.8 0.25 10.8 0.5 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein PduV-EutP PF10662.9 CAR26262.1 - 0.11 12.2 0.2 10 5.9 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 CAR26262.1 - 0.14 12.2 5.8 2.5 8.1 0.6 3.3 2 1 1 3 3 3 0 Helicase HerA, central domain Zeta_toxin PF06414.12 CAR26262.1 - 0.17 11.2 0.3 6.6 6.0 0.2 2.3 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 CAR26262.1 - 0.21 11.3 1.4 6.5 6.5 0.1 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.6 CAR26262.1 - 0.32 9.6 0.6 4.6 5.8 0.1 2.6 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 CAR26262.1 - 0.35 10.2 1.3 1.2 8.4 0.1 2.5 4 0 0 4 4 3 0 KaiC SbcCD_C PF13558.6 CAR26262.1 - 0.63 10.3 2.3 51 4.2 0.1 3.6 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 CAR26262.1 - 1.9 8.5 7.1 3.7 7.6 1.0 2.6 2 0 0 2 2 2 0 Dynamin family Haem_degrading PF03928.14 CAR26263.1 - 1.4e-30 105.7 0.0 1.7e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading NatB_MDM20 PF09797.9 CAR26265.1 - 4.2e-40 137.9 6.0 1.2e-38 133.1 6.0 2.4 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_7 PF13176.6 CAR26265.1 - 0.099 12.7 0.3 0.61 10.2 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Brix PF04427.18 CAR26266.1 - 5.6e-40 137.5 0.6 8e-40 137.0 0.6 1.2 1 0 0 1 1 1 1 Brix domain Nucleopor_Nup85 PF07575.13 CAR26266.1 - 0.086 11.4 0.2 0.11 11.0 0.2 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin PCP_red PF08369.10 CAR26266.1 - 0.1 12.8 0.4 0.26 11.6 0.4 1.7 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit ATP19 PF11022.8 CAR26267.1 - 3.9e-22 78.4 0.0 4.3e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K Peptidase_S10 PF00450.22 CAR26268.1 - 2.5e-124 415.9 0.1 3e-124 415.6 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CRIM PF16978.5 CAR26269.1 - 2.2e-38 131.6 2.6 1.1e-34 119.6 0.5 2.8 2 0 0 2 2 2 2 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 CAR26269.1 - 3.1e-31 107.9 0.2 3.1e-31 107.9 0.2 2.6 3 0 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 CAR26269.1 - 0.055 13.6 0.0 0.19 11.8 0.0 1.9 1 0 0 1 1 1 0 Raf-like Ras-binding domain RNase_T PF00929.24 CAR26270.1 - 6.5e-16 59.3 0.1 5.2e-14 53.1 0.0 2.3 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CAR26270.1 - 0.0018 18.0 0.0 0.0053 16.5 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Chrome_Resist PF09828.9 CAR26270.1 - 0.057 13.9 0.1 0.11 13.0 0.1 1.4 1 0 0 1 1 1 0 Chromate resistance exported protein Tox-MPTase3 PF15639.6 CAR26270.1 - 0.07 13.0 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 3 DALR_2 PF09190.11 CAR26270.1 - 0.19 12.2 0.0 10 6.7 0.0 2.4 2 0 0 2 2 2 0 DALR domain RasGAP PF00616.19 CAR26271.1 - 2.4e-20 73.2 0.6 9e-12 45.1 0.1 3.0 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase Bmt2 PF11968.8 CAR26272.1 - 1.9e-82 276.4 0.0 2.7e-82 275.9 0.0 1.2 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 CAR26272.1 - 0.013 15.3 0.0 0.036 13.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CAR26272.1 - 0.1 13.3 0.0 0.19 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 CAR26273.1 - 1.4e-37 129.2 0.0 3.9e-37 127.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR26273.1 - 7.1e-31 106.8 1.7 9e-27 93.6 0.0 3.5 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CAR26273.1 - 1.4e-05 25.1 0.0 1.4e-05 25.1 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 CAR26273.1 - 0.015 15.4 2.4 0.42 10.8 0.0 3.6 4 0 0 4 4 4 0 Helicase C-terminal domain ASC PF00858.24 CAR26273.1 - 0.025 13.6 0.3 0.047 12.7 0.3 1.4 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Zip PF02535.22 CAR26273.1 - 0.082 12.1 6.0 0.17 11.0 6.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Spt20 PF12090.8 CAR26273.1 - 0.66 9.5 19.8 2.5 7.6 19.8 2.0 1 0 0 1 1 1 0 Spt20 family Endostatin PF06482.11 CAR26273.1 - 1.1 8.7 6.7 1.4 8.3 5.3 1.8 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin SAPS PF04499.15 CAR26273.1 - 5.7 5.6 17.5 0.39 9.4 11.4 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 CAR26273.1 - 7.7 4.5 12.5 14 3.6 12.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eRF1_2 PF03464.15 CAR26274.1 - 1.4e-45 154.9 0.1 2.7e-45 153.9 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CAR26274.1 - 9.5e-38 129.2 0.3 1.9e-37 128.2 0.3 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CAR26274.1 - 3.5e-20 72.3 0.0 5.7e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CAR26274.1 - 1.9e-09 37.9 0.0 2.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CAR26274.1 - 2.4e-09 37.6 0.0 3.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 ATG19_autophagy PF12744.7 CAR26275.1 - 6.1e-21 74.7 0.2 3.4e-17 62.5 0.0 2.3 1 1 1 2 2 2 2 Autophagy protein Atg19, Atg8-binding ZZ PF00569.17 CAR26275.1 - 7.6e-08 32.0 4.4 7.6e-08 32.0 4.4 2.1 2 0 0 2 2 2 1 Zinc finger, ZZ type TACC_C PF05010.14 CAR26275.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal RSN1_7TM PF02714.15 CAR26276.1 - 6.6e-89 297.9 18.2 6.6e-89 297.9 18.2 1.8 2 1 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CAR26276.1 - 1.3e-39 135.5 2.8 1.8e-39 135.0 1.1 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 CAR26276.1 - 1.8e-24 85.7 0.2 3.4e-24 84.8 0.2 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 CAR26276.1 - 1.5e-21 77.5 0.1 2.3e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter ADH_N PF08240.12 CAR26277.1 - 1.3e-29 102.3 1.5 3.2e-29 101.0 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR26277.1 - 2.9e-21 75.8 2.4 4.5e-21 75.2 2.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR26277.1 - 6.9e-05 23.9 0.1 0.00012 23.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CAR26277.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YbjQ_1 PF01906.17 CAR26277.1 - 0.72 10.5 3.5 0.51 11.0 1.3 1.9 2 0 0 2 2 2 0 Putative heavy-metal-binding Ribosomal_S9 PF00380.19 CAR26278.1 - 9.4e-42 142.4 0.2 1.7e-41 141.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2277 PF10041.9 CAR26278.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) DUF3337 PF11816.8 CAR26279.1 - 5.2e-32 111.1 0.3 1.5e-31 109.5 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 CAR26279.1 - 0.00011 22.9 4.4 0.83 10.6 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat RAWUL PF16207.5 CAR26279.1 - 0.0069 17.0 0.1 0.016 15.8 0.1 1.7 1 0 0 1 1 1 1 RAWUL domain RING finger- and WD40-associated ubiquitin-like Rad60-SLD_2 PF13881.6 CAR26279.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RNA_pol_Rpb5_C PF01191.19 CAR26280.1 - 6.4e-31 106.1 0.2 1.2e-30 105.2 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CAR26280.1 - 1.2e-28 99.5 0.2 2.2e-28 98.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 CAR26280.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease Sof1 PF04158.14 CAR26280.1 - 0.062 13.6 0.3 0.13 12.6 0.3 1.5 1 0 0 1 1 1 0 Sof1-like domain SH3_2 PF07653.17 CAR26280.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain RibD_C PF01872.17 CAR26281.1 - 5e-35 121.1 0.0 5.8e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain MFAP1 PF06991.11 CAR26282.1 - 1.4e-05 25.1 7.8 2.1e-05 24.5 7.8 1.2 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing DUF3316 PF11777.8 CAR26282.1 - 0.1 12.7 1.5 0.98 9.5 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3316) NICE-1 PF15845.5 CAR26282.1 - 0.16 12.8 0.5 0.34 11.7 0.5 1.5 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family Pyrid_oxidase_2 PF13883.6 CAR26283.1 - 4.1e-35 121.2 0.0 5.1e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Thioredoxin PF00085.20 CAR26284.1 - 1.6e-09 37.7 0.1 6.5e-09 35.7 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin Suc_Fer-like PF06999.12 CAR26285.1 - 3.1e-48 164.3 0.0 4e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Aldo_ket_red PF00248.21 CAR26286.1 - 4.8e-35 121.2 0.1 3.1e-33 115.2 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MutS_V PF00488.21 CAR26287.1 - 1e-84 283.3 0.1 2.1e-84 282.3 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAR26287.1 - 1.2e-31 110.5 1.4 1.2e-31 110.5 1.4 2.2 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CAR26287.1 - 1.2e-20 74.1 2.0 1.9e-20 73.5 0.2 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 CAR26287.1 - 1.4e-17 63.8 0.7 5.1e-17 62.0 0.7 2.1 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 CAR26287.1 - 7.2e-10 39.1 0.1 6.8e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 MutS domain I AAA_27 PF13514.6 CAR26287.1 - 0.077 12.6 0.0 0.29 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Herpes_BLRF2 PF05812.12 CAR26287.1 - 0.078 13.1 2.7 0.11 12.6 0.3 2.3 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Terminase_4 PF05119.12 CAR26287.1 - 0.11 13.0 0.0 0.46 11.0 0.0 2.1 1 0 0 1 1 1 0 Phage terminase, small subunit HALZ PF02183.18 CAR26288.1 - 2.3e-06 27.7 42.5 0.0051 17.0 0.4 8.6 6 2 3 9 9 9 5 Homeobox associated leucine zipper GAS PF13851.6 CAR26288.1 - 0.0025 17.2 12.9 0.0025 17.2 12.9 5.6 4 1 1 5 5 5 2 Growth-arrest specific micro-tubule binding Utp12 PF04003.12 CAR26288.1 - 0.043 14.1 0.7 0.22 11.8 0.1 2.7 2 0 0 2 2 2 0 Dip2/Utp12 Family CENP-F_leu_zip PF10473.9 CAR26288.1 - 0.059 13.4 60.0 0.016 15.2 11.3 6.1 4 1 3 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.9 CAR26288.1 - 0.78 9.0 55.2 1.7 7.9 10.9 4.5 2 1 2 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) LPP PF04728.13 CAR26288.1 - 1.3 9.5 18.1 1.8 9.0 0.1 6.0 4 1 2 6 6 6 0 Lipoprotein leucine-zipper PQ-loop PF04193.14 CAR26289.1 - 2.8e-39 132.7 20.5 6.3e-22 77.1 1.0 3.4 4 0 0 4 4 4 2 PQ loop repeat Steroid_dh PF02544.16 CAR26289.1 - 0.61 10.1 5.1 0.22 11.5 1.1 2.3 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase tRNA_m1G_MT PF01746.21 CAR26290.1 - 1.8e-38 132.2 0.1 2.7e-38 131.6 0.1 1.3 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Rep_fac_C PF08542.11 CAR26291.1 - 6.9e-19 68.1 0.1 2.6e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CAR26291.1 - 4.2e-14 52.7 0.1 9.1e-11 41.8 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 CAR26291.1 - 3.3e-13 50.2 0.0 6.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAR26291.1 - 2e-07 31.6 0.0 5.4e-05 23.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CAR26291.1 - 6.6e-07 29.4 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAR26291.1 - 8.4e-06 26.1 0.1 0.022 15.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 CAR26291.1 - 1.1e-05 25.3 0.0 2.8e-05 24.0 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CAR26291.1 - 2.6e-05 24.1 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 CAR26291.1 - 6.9e-05 22.9 0.0 0.00023 21.2 0.0 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 CAR26291.1 - 0.00012 21.9 0.8 0.00021 21.1 0.8 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 CAR26291.1 - 0.00015 21.5 0.1 0.00037 20.3 0.1 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 CAR26291.1 - 0.00051 19.5 0.1 1 8.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein Mg_chelatase PF01078.21 CAR26291.1 - 0.0015 18.0 0.1 0.024 14.0 0.1 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 CAR26291.1 - 0.0041 17.4 0.0 0.011 16.0 0.0 1.8 2 0 0 2 2 1 1 AAA C-terminal domain MeaB PF03308.16 CAR26291.1 - 0.013 14.5 0.0 0.11 11.5 0.0 2.2 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 CAR26291.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CAR26291.1 - 0.018 15.0 0.1 0.14 12.1 0.0 2.2 1 1 1 2 2 2 0 NTPase AAA_19 PF13245.6 CAR26291.1 - 0.038 14.3 0.2 0.62 10.4 0.0 2.4 1 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CAR26291.1 - 0.067 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NapD PF03927.13 CAR26291.1 - 0.076 13.1 0.1 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 NapD protein KTI12 PF08433.10 CAR26291.1 - 0.1 12.0 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 CAR26291.1 - 0.11 12.2 0.0 0.43 10.3 0.0 2.0 1 1 0 1 1 1 0 AAA domain Ins_P5_2-kin PF06090.12 CAR26291.1 - 0.13 11.6 0.1 0.25 10.7 0.1 1.3 1 1 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase ChapFlgA_N PF17656.1 CAR26291.1 - 0.15 12.2 0.0 0.49 10.6 0.0 1.9 2 0 0 2 2 2 0 FlgA N-terminal domain Vps52 PF04129.12 CAR26292.1 - 9.9e-129 430.4 20.5 1.3e-128 430.0 20.5 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family CENP-F_leu_zip PF10473.9 CAR26292.1 - 0.0065 16.5 0.9 0.017 15.2 0.9 1.7 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ApoLp-III PF07464.11 CAR26292.1 - 0.0099 16.0 0.2 5.9 7.0 0.1 2.8 2 0 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) CortBP2 PF09727.9 CAR26292.1 - 0.4 10.6 4.0 0.59 10.0 0.9 2.5 2 0 0 2 2 2 0 Cortactin-binding protein-2 CCDC144C PF14915.6 CAR26292.1 - 1.3 8.0 9.0 0.22 10.6 1.7 2.7 3 0 0 3 3 3 0 CCDC144C protein coiled-coil region UvrD-helicase PF00580.21 CAR26293.1 - 4.8e-32 111.7 0.1 1.6e-15 57.5 0.0 2.5 1 1 1 2 2 2 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CAR26293.1 - 2.5e-30 106.1 0.0 6.2e-30 104.8 0.0 1.7 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CAR26293.1 - 5.4e-27 94.9 0.0 1e-26 94.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CAR26293.1 - 1.1e-12 47.5 0.0 2.4e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 CAR26293.1 - 4.3e-10 39.8 0.0 7.1e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CAR26293.1 - 5.2e-10 39.5 0.0 0.0005 19.9 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 CAR26293.1 - 7.2e-05 22.6 0.0 0.024 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CAR26293.1 - 0.0031 17.8 0.1 1.2 9.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain YL1 PF05764.13 CAR26294.1 - 3e-52 178.2 48.1 3e-52 178.2 48.1 2.8 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 CAR26294.1 - 1.4e-11 43.9 0.3 2.3e-11 43.2 0.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Methyltransf_23 PF13489.6 CAR26295.1 - 8.8e-24 84.2 0.0 1.4e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR26295.1 - 2.3e-17 63.4 0.0 3.8e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR26295.1 - 7.6e-16 58.3 0.0 1.1e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR26295.1 - 1.4e-15 57.8 0.0 2.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR26295.1 - 5.7e-15 55.9 0.0 1e-14 55.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CAR26295.1 - 1.7e-07 30.9 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 CAR26295.1 - 2.2e-07 30.6 0.0 3.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CAR26295.1 - 7.6e-07 28.8 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 CAR26295.1 - 1.4e-05 24.8 0.0 9.5e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 CAR26295.1 - 4e-05 23.1 0.0 5.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CAR26295.1 - 0.00043 20.3 0.0 0.00065 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 CAR26295.1 - 0.0018 17.5 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 CAR26295.1 - 0.0038 17.0 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 CAR26295.1 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CAR26295.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_8 PF05148.15 CAR26295.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase AviRa PF11599.8 CAR26295.1 - 0.041 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Snf7 PF03357.21 CAR26296.1 - 5.6e-41 140.0 16.4 7.5e-41 139.6 16.4 1.1 1 0 0 1 1 1 1 Snf7 Fmp27_WPPW PF10359.9 CAR26296.1 - 0.00089 18.2 9.7 0.00089 18.2 9.7 1.5 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain YlqD PF11068.8 CAR26296.1 - 0.0081 16.5 12.5 0.0081 16.5 12.5 2.2 1 1 1 2 2 2 1 YlqD protein CdvA PF18822.1 CAR26296.1 - 0.014 15.2 13.4 0.25 11.2 1.4 3.1 1 1 1 2 2 2 0 CdvA-like coiled-coil domain DUF5082 PF16888.5 CAR26296.1 - 0.016 15.4 1.2 0.016 15.4 1.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Cep57_MT_bd PF06657.13 CAR26296.1 - 0.037 14.5 5.1 0.037 14.5 5.1 2.8 3 1 1 4 4 3 0 Centrosome microtubule-binding domain of Cep57 Fib_alpha PF08702.10 CAR26296.1 - 0.042 14.0 14.0 1.3 9.2 0.4 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1732 PF08340.11 CAR26296.1 - 0.056 13.4 2.3 0.089 12.8 1.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) Glutaredoxin PF00462.24 CAR26296.1 - 0.063 13.5 1.6 6.2 7.1 0.1 2.6 1 1 1 2 2 2 0 Glutaredoxin SKA1 PF07160.12 CAR26296.1 - 0.093 12.6 13.8 0.059 13.2 10.4 1.8 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 CENP-F_leu_zip PF10473.9 CAR26296.1 - 0.14 12.2 16.0 0.14 12.2 0.6 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PhoU PF01895.19 CAR26296.1 - 0.24 11.9 5.2 0.24 11.9 0.1 2.7 1 1 1 2 2 2 0 PhoU domain LPP PF04728.13 CAR26296.1 - 0.32 11.4 0.3 0.32 11.4 0.3 3.7 2 1 0 2 2 1 0 Lipoprotein leucine-zipper Not3 PF04065.15 CAR26296.1 - 0.47 9.8 13.5 2.1 7.7 13.5 1.9 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component FlaC_arch PF05377.11 CAR26296.1 - 0.55 10.7 7.0 2.4 8.6 0.1 3.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 CAR26296.1 - 0.86 9.1 13.9 1.3 8.5 13.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit FliJ PF02050.16 CAR26296.1 - 0.9 9.8 21.0 0.17 12.1 12.7 2.5 1 1 2 3 3 3 0 Flagellar FliJ protein TMF_DNA_bd PF12329.8 CAR26296.1 - 1.6 8.8 14.4 2.2 8.3 0.4 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 CAR26296.1 - 2.1 8.5 14.8 0.44 10.7 10.8 1.8 1 1 1 2 2 2 0 Tropomyosin like Serine_rich PF08824.10 CAR26296.1 - 2.2 8.3 18.8 0.25 11.3 7.6 2.7 1 1 1 2 2 2 0 Serine rich protein interaction domain Sec34 PF04136.15 CAR26296.1 - 2.3 8.1 13.3 6.9 6.5 6.2 2.4 1 1 0 2 2 2 0 Sec34-like family CENP-O PF09496.10 CAR26296.1 - 2.7 7.9 8.1 7.2 6.5 8.1 1.7 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component YabA PF06156.13 CAR26296.1 - 3.2 8.4 12.1 51 4.6 1.5 2.9 1 1 1 2 2 2 0 Initiation control protein YabA Jnk-SapK_ap_N PF09744.9 CAR26296.1 - 4.4 7.5 19.1 0.63 10.3 3.7 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 tRNA-synt_1b PF00579.25 CAR26297.1 - 1.8e-17 63.6 0.0 1.4e-16 60.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) DHBP_synthase PF00926.19 CAR26298.1 - 6e-84 280.4 0.0 6.8e-84 280.2 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase WD40 PF00400.32 CAR26299.1 - 0.0064 17.3 0.4 0.29 12.1 0.4 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat SLD5_C PF16922.5 CAR26300.1 - 9.5e-22 77.0 0.0 1.8e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CAR26300.1 - 4.3e-11 43.2 1.7 9.4e-11 42.1 1.4 1.8 2 0 0 2 2 2 1 GINS complex protein Peptidase_M16_C PF05193.21 CAR26301.1 - 3.1e-12 46.9 0.0 4.5e-11 43.1 0.0 2.8 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CAR26301.1 - 2.2e-10 40.7 0.0 9.4e-09 35.4 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) UPF0728 PF15092.6 CAR26301.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 TusA PF01206.17 CAR26301.1 - 0.16 11.9 0.0 0.52 10.2 0.0 2.0 1 0 0 1 1 1 0 Sulfurtransferase TusA Pkinase PF00069.25 CAR26302.1 - 1.4e-60 204.9 0.2 2.9e-60 203.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR26302.1 - 1e-33 116.7 0.0 1.5e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR26302.1 - 2.3e-08 33.7 0.0 5.3e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAR26302.1 - 5.5e-06 25.4 0.7 1.8e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 CAR26302.1 - 3e-05 23.7 0.3 0.094 12.3 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CAR26302.1 - 0.0016 17.8 0.0 0.004 16.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAR26302.1 - 0.015 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain AAA_14 PF13173.6 CAR26302.1 - 0.024 14.7 0.1 0.052 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain RIO1 PF01163.22 CAR26302.1 - 0.034 13.8 0.3 0.12 12.0 0.3 1.9 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 CAR26302.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HlyIII PF03006.20 CAR26304.1 - 3.2e-56 190.6 19.5 3.8e-56 190.3 19.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related PTS_2-RNA PF01885.16 CAR26306.1 - 9.6e-56 188.7 0.4 1.4e-55 188.2 0.4 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.17 CAR26306.1 - 0.044 13.8 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 La domain SPK PF04435.18 CAR26308.1 - 0.036 14.5 1.9 0.11 12.9 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF545) CPL PF08144.11 CAR26309.1 - 1.8e-49 167.8 0.2 1.3e-46 158.5 0.0 3.8 5 0 0 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 CAR26309.1 - 0.018 14.7 1.3 12 5.8 0.0 5.0 6 0 0 6 6 6 0 Pumilio-family RNA binding repeat SAC3 PF12209.8 CAR26309.1 - 0.048 13.9 5.3 5.6 7.2 0.0 4.1 4 1 1 5 5 5 0 Leucine permease transcriptional regulator helical domain CDC45 PF02724.14 CAR26309.1 - 4.7 5.4 13.4 8.3 4.6 13.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Sugar_tr PF00083.24 CAR26310.1 - 3.5e-129 431.6 24.3 4.2e-129 431.3 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR26310.1 - 1.9e-33 115.8 28.8 1.5e-30 106.3 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CAR26310.1 - 5.5e-07 28.4 3.0 5.5e-07 28.4 3.0 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CAR26310.1 - 0.00087 17.8 0.8 0.00087 17.8 0.8 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector Sec20 PF03908.13 CAR26311.1 - 1e-27 95.8 0.9 1e-27 95.8 0.9 3.0 4 0 0 4 4 4 1 Sec20 ORC_WH_C PF18137.1 CAR26311.1 - 0.037 14.1 1.0 0.088 12.9 1.0 1.7 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal ERG4_ERG24 PF01222.17 CAR26313.1 - 8.6e-162 538.8 8.1 9.7e-162 538.6 8.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CAR26313.1 - 0.0022 17.6 0.4 0.0022 17.6 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) DDE_Tnp_Tn3 PF01526.17 CAR26313.1 - 0.021 13.6 0.0 0.029 13.1 0.0 1.1 1 0 0 1 1 1 0 Tn3 transposase DDE domain TMEM40 PF15817.5 CAR26313.1 - 2.6 7.8 6.9 37 4.1 0.0 3.4 3 0 0 3 3 3 0 Transmembrane protein 40 family Aha1_N PF09229.11 CAR26314.1 - 1.1e-28 100.1 0.0 1.3e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal RNase_P_pop3 PF08228.11 CAR26315.1 - 1.2e-40 139.1 0.9 1.6e-40 138.8 0.9 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 WSC PF01822.19 CAR26316.1 - 4.3e-12 46.1 9.5 1.4e-11 44.5 9.5 1.9 1 0 0 1 1 1 1 WSC domain PTP_tm PF18861.1 CAR26316.1 - 0.00014 21.9 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4690 PF15756.5 CAR26316.1 - 0.0036 17.9 1.2 0.0036 17.9 1.2 2.5 2 1 1 3 3 3 1 Small Novel Rich in Cartilage SKG6 PF08693.10 CAR26316.1 - 0.19 11.1 7.6 0.43 10.0 7.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ribosomal_L27A PF00828.19 CAR26317.1 - 4.9e-34 117.8 3.1 2e-33 115.8 0.4 2.2 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF1751 PF08551.10 CAR26318.1 - 1.2e-28 99.6 2.4 1.2e-28 99.6 2.4 1.8 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) HLH PF00010.26 CAR26319.1 - 0.00093 19.1 0.4 0.00093 19.1 0.4 2.0 1 1 1 2 2 2 1 Helix-loop-helix DNA-binding domain MIF4G_like_2 PF09090.11 CAR26319.1 - 0.013 15.0 2.6 0.022 14.3 2.6 1.4 1 0 0 1 1 1 0 MIF4G like RRM_1 PF00076.22 CAR26320.1 - 8.9e-19 67.1 0.5 5e-10 39.1 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR26320.1 - 0.00027 20.5 0.1 0.022 14.3 0.1 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR26320.1 - 0.019 15.0 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Hfq PF17209.3 CAR26320.1 - 0.064 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Hfq protein Adaptin_N PF01602.20 CAR26321.1 - 8.7e-115 384.2 11.5 1.1e-114 383.9 11.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CAR26321.1 - 8.2e-45 152.6 1.0 8.2e-45 152.6 1.0 2.2 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CAR26321.1 - 3.9e-30 104.3 0.0 9.9e-30 103.0 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CAR26321.1 - 1.7e-13 50.7 0.9 4.3e-07 30.2 0.1 4.7 3 2 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 CAR26321.1 - 1.4e-06 28.4 7.4 0.0018 18.3 0.0 4.1 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CAR26321.1 - 0.0012 18.9 3.5 6.4 7.3 0.1 5.9 7 0 0 7 7 7 1 HEAT repeat Dioxygenase_N PF04444.14 CAR26321.1 - 0.13 12.2 0.1 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 Catechol dioxygenase N terminus HEAT_EZ PF13513.6 CAR26321.1 - 0.17 12.4 0.3 2.9 8.5 0.2 3.3 3 1 0 3 3 3 0 HEAT-like repeat CobT PF06213.12 CAR26322.1 - 0.00097 18.6 4.3 0.001 18.6 4.3 1.1 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Zip PF02535.22 CAR26322.1 - 0.11 11.7 0.7 0.12 11.5 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 CAR26322.1 - 0.16 11.7 8.6 0.19 11.5 8.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 CAR26322.1 - 0.17 10.8 1.8 0.17 10.8 1.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CAR26322.1 - 0.26 10.0 5.0 0.25 10.1 5.0 1.2 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 CAR26322.1 - 6.9 6.4 11.7 9.8 5.9 11.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Rcd1 PF04078.13 CAR26323.1 - 7.9e-113 376.0 4.7 9.4e-113 375.8 4.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like SRX PF09201.10 CAR26323.1 - 0.016 15.0 0.0 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 SRX, signal recognition particle receptor alpha subunit EIIBC-GUT_N PF03612.14 CAR26324.1 - 0.63 9.8 5.1 0.63 9.8 5.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SseC PF04888.12 CAR26324.1 - 0.64 9.6 7.1 0.72 9.4 7.1 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family UPF0242 PF06785.11 CAR26324.1 - 0.74 9.9 10.1 0.85 9.7 10.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3292 PF11696.8 CAR26324.1 - 1 7.6 7.2 1.1 7.5 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Y_phosphatase3 PF13350.6 CAR26325.1 - 1.4e-55 188.8 0.0 2e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Hydrolase_4 PF12146.8 CAR26325.1 - 6.1e-07 29.0 0.0 1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PTPlike_phytase PF14566.6 CAR26325.1 - 0.0094 16.1 0.1 0.026 14.6 0.1 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 CAR26325.1 - 0.03 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Abhydrolase_6 PF12697.7 CAR26325.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ank_4 PF13637.6 CAR26326.1 - 2.8e-13 50.1 2.8 1e-06 29.1 0.0 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR26326.1 - 1.3e-12 48.2 0.0 1.3e-05 25.7 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAR26326.1 - 3e-09 37.0 4.0 0.0014 18.9 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAR26326.1 - 3.8e-09 36.0 0.2 0.024 15.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CAR26326.1 - 3.1e-08 33.7 0.0 0.26 11.8 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat KilA-N PF04383.13 CAR26326.1 - 7.4e-07 29.0 0.1 7.4e-07 29.0 0.1 2.7 2 1 0 2 2 2 1 KilA-N domain Noelin-1 PF12308.8 CAR26326.1 - 0.086 12.8 0.2 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein IZUMO PF15005.6 CAR26326.1 - 0.55 10.7 2.6 1.7 9.2 2.6 1.8 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated Cytochrom_B562 PF07361.11 CAR26326.1 - 2 9.1 5.6 0.43 11.3 1.3 2.2 2 0 0 2 2 2 0 Cytochrome b562 COG5 PF10392.9 CAR26326.1 - 7.3 6.8 9.7 0.29 11.3 0.3 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 NTP_transferase PF00483.23 CAR26327.1 - 2.3e-53 181.3 0.0 2.9e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CAR26327.1 - 1e-10 42.2 0.0 1.4e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 CAR26327.1 - 3.4e-08 32.9 7.2 1.1e-07 31.3 1.4 3.4 1 1 1 3 3 3 1 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 CAR26327.1 - 0.0031 15.7 0.3 0.0046 15.2 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 CAR26327.1 - 0.014 14.4 0.1 0.047 12.6 0.1 1.8 2 0 0 2 2 2 0 L-fucokinase Hexapep_2 PF14602.6 CAR26327.1 - 0.025 14.3 3.5 0.049 13.4 0.4 2.9 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 CAR26327.1 - 0.097 12.4 0.0 0.56 9.9 0.0 2.1 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FA_hydroxylase PF04116.13 CAR26328.1 - 2.5e-26 92.6 22.2 2.5e-26 92.6 22.2 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_hydro_85 PF03644.13 CAR26329.1 - 2e-72 244.2 7.4 2.7e-72 243.7 7.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Spc24 PF08286.11 CAR26329.1 - 0.27 11.5 2.2 0.36 11.1 0.8 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SecY PF00344.20 CAR26330.1 - 7.2e-63 212.7 12.1 9.5e-63 212.3 12.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CAR26330.1 - 8.2e-18 64.0 0.2 4.2e-17 61.7 0.2 2.4 1 0 0 1 1 1 1 Plug domain of Sec61p Claudin_3 PF06653.11 CAR26330.1 - 0.29 11.1 0.0 0.29 11.1 0.0 3.1 3 1 0 3 3 3 0 Tight junction protein, Claudin-like DUF2975 PF11188.8 CAR26330.1 - 1.3 8.9 7.1 0.37 10.7 1.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Cation_ATPase_C PF00689.21 CAR26330.1 - 2 8.1 9.9 2.8 7.6 0.9 2.7 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus MFS_1 PF07690.16 CAR26331.1 - 1.6e-11 43.8 30.9 2.8e-11 43.0 30.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5393 PF17371.2 CAR26332.1 - 0.27 9.3 4.8 0.27 9.3 4.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) APC_basic PF05956.11 CAR26332.1 - 0.84 9.0 30.2 0.69 9.3 29.1 1.3 1 1 0 1 1 1 0 APC basic domain DUF2561 PF10812.8 CAR26332.1 - 1.2 9.2 2.3 1.6 8.7 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Macoilin PF09726.9 CAR26332.1 - 1.8 7.0 20.1 1.9 7.0 20.1 1.0 1 0 0 1 1 1 0 Macoilin family FBPase PF00316.20 CAR26333.1 - 2.9e-80 268.2 0.2 3.7e-80 267.9 0.2 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 CAR26333.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family Acyltransferase PF01553.21 CAR26334.1 - 6.7e-33 113.2 0.0 1e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Glyco_trans_1_3 PF13528.6 CAR26334.1 - 0.0059 15.9 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 PSY3 PF16836.5 CAR26335.1 - 1.4e-79 266.7 1.5 1.6e-79 266.5 1.5 1.0 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description DUF835 PF05763.12 CAR26335.1 - 0.091 12.5 0.1 0.2 11.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF835) DUF3944 PF13099.6 CAR26335.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) La PF05383.17 CAR26336.1 - 4.7e-22 77.8 0.0 1.2e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CAR26336.1 - 3.4e-07 30.0 1.0 1.3e-06 28.2 0.2 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PikAIV_N PF18605.1 CAR26336.1 - 0.021 14.4 0.1 0.021 14.4 0.1 2.0 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain KRE9 PF05390.11 CAR26337.1 - 1.4e-44 151.0 4.9 3e-44 149.9 4.9 1.6 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CAR26337.1 - 5.1e-10 40.0 0.3 1.2e-09 38.8 0.1 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NAR2 PF16974.5 CAR26337.1 - 0.028 13.8 0.0 4 6.8 0.0 2.3 2 0 0 2 2 2 0 High-affinity nitrate transporter accessory FA_desaturase PF00487.24 CAR26338.1 - 3.2e-21 76.3 26.0 8.8e-21 74.9 26.0 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 CAR26338.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) CCB1 PF12046.8 CAR26338.1 - 0.31 10.4 1.2 0.48 9.8 0.1 1.8 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B zf-C2H2_4 PF13894.6 CAR26339.1 - 1.2e-06 28.9 26.1 0.00024 21.7 0.9 5.1 5 0 0 5 5 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CAR26339.1 - 0.00023 21.1 12.5 0.00042 20.3 0.3 4.1 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CAR26339.1 - 0.00032 21.0 1.8 0.00032 21.0 1.8 5.0 4 1 0 4 4 4 1 Zinc finger, C2H2 type Zn-C2H2_12 PF18112.1 CAR26339.1 - 0.0013 19.2 0.2 1.1 9.8 0.0 3.2 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 CAR26339.1 - 0.0073 16.6 8.2 0.022 15.1 4.5 3.4 3 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CAR26339.1 - 0.016 15.5 6.8 0.02 15.1 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CAR26339.1 - 0.052 14.0 2.4 0.052 14.0 2.4 5.0 4 1 1 5 5 5 0 Zinc-finger double domain Prok-RING_1 PF14446.6 CAR26339.1 - 0.14 12.1 2.0 3.4 7.7 0.0 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.14 CAR26339.1 - 0.15 11.9 2.1 0.75 9.7 0.1 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif Serglycin PF04360.12 CAR26339.1 - 0.17 11.8 2.1 0.49 10.3 0.6 2.2 2 0 0 2 2 2 0 Serglycin Prok-RING_4 PF14447.6 CAR26339.1 - 0.27 11.2 5.6 3.5 7.6 0.2 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAR26339.1 - 0.3 11.1 4.0 13 5.8 0.1 3.2 3 0 0 3 3 3 0 zinc-RING finger domain HypA PF01155.19 CAR26339.1 - 0.35 10.9 1.5 3.9 7.5 0.0 2.4 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 CAR26339.1 - 0.71 10.2 4.5 1.7 9.0 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon TRAF6_Z2 PF18048.1 CAR26339.1 - 0.95 9.6 7.4 2 8.6 0.1 4.0 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 zf-C3HC4_3 PF13920.6 CAR26339.1 - 2.8 7.9 11.6 8.4 6.3 1.0 3.3 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.7 CAR26339.1 - 3.6 8.1 7.8 0.45 11.0 0.3 3.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type ELO PF01151.18 CAR26340.1 - 1.6e-58 198.2 25.2 2e-58 197.9 25.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF92 PF01940.16 CAR26340.1 - 0.3 10.5 2.3 0.21 11.0 0.3 1.8 2 0 0 2 2 2 0 Integral membrane protein DUF92 MARVEL PF01284.23 CAR26340.1 - 0.56 10.2 10.4 2 8.5 0.3 2.4 2 1 0 2 2 2 0 Membrane-associating domain CNH PF00780.22 CAR26341.1 - 3.1e-78 263.2 0.7 5.1e-78 262.5 0.1 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 CAR26341.1 - 4.6e-38 130.4 0.0 1.7e-37 128.5 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 CAR26341.1 - 7e-29 101.4 0.4 1.9e-28 99.9 0.0 2.0 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.21 CAR26341.1 - 1.5e-13 50.6 0.0 3.9e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) P21-Arc PF04062.14 CAR26342.1 - 1.6e-65 220.4 0.0 1.8e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit HSP70 PF00012.20 CAR26343.1 - 3.9e-217 722.2 8.6 4.7e-217 721.9 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR26343.1 - 2.1e-16 59.7 1.3 9.4e-14 50.9 0.2 2.6 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CAR26343.1 - 0.0006 19.6 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain GARP PF16731.5 CAR26343.1 - 0.011 15.4 0.8 0.094 12.4 0.0 2.3 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF763 PF05559.11 CAR26343.1 - 0.18 10.9 1.2 1.6 7.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF763) Terminase_2 PF03592.16 CAR26343.1 - 3.5 8.1 11.4 0.33 11.4 3.7 2.6 3 0 0 3 3 3 0 Terminase small subunit F-box PF00646.33 CAR26344.1 - 4.9e-05 23.1 1.1 0.00021 21.0 1.1 2.2 1 0 0 1 1 1 1 F-box domain CelTOS PF18659.1 CAR26344.1 - 0.14 12.6 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites F-box-like PF12937.7 CAR26344.1 - 0.92 9.5 3.9 1.3 8.9 1.1 2.6 3 0 0 3 3 3 0 F-box-like zf-C2H2 PF00096.26 CAR26345.1 - 2.7e-08 33.8 12.2 0.00016 22.0 1.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR26345.1 - 3.5e-07 30.4 17.7 1.8e-05 24.9 4.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR26345.1 - 0.0001 22.8 12.0 0.02 15.7 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger PHD_4 PF16866.5 CAR26345.1 - 0.15 12.2 0.2 0.42 10.7 0.2 1.7 1 0 0 1 1 1 0 PHD-finger zf-C2H2_jaz PF12171.8 CAR26345.1 - 0.18 12.1 5.1 7.8 6.9 2.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CAR26345.1 - 0.74 10.2 3.5 1.5 9.1 3.5 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 CAR26345.1 - 2 8.5 6.6 6.1 7.0 0.6 3.2 2 1 1 3 3 3 0 BED zinc finger Ribosomal_S8 PF00410.19 CAR26346.1 - 3.1e-23 82.1 0.1 4.2e-23 81.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 MFS_1 PF07690.16 CAR26347.1 - 5e-19 68.4 19.2 3.6e-17 62.3 17.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily KdgM PF06178.13 CAR26347.1 - 0.12 12.0 6.2 0.21 11.2 6.2 1.3 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) Glutaredoxin PF00462.24 CAR26348.1 - 3.8e-06 27.0 0.0 1.5e-05 25.1 0.0 2.0 2 1 1 3 3 3 1 Glutaredoxin Thioredoxin PF00085.20 CAR26348.1 - 0.00058 19.8 0.0 0.00069 19.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Prd1-P2 PF09214.11 CAR26348.1 - 0.0019 17.1 0.0 0.0021 16.9 0.0 1.0 1 0 0 1 1 1 1 Bacteriophage Prd1, adsorption protein P2 Thioredoxin_9 PF14595.6 CAR26348.1 - 0.0024 17.6 0.0 0.0027 17.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CAR26348.1 - 0.01 16.3 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain DUF953 PF06110.11 CAR26348.1 - 0.03 14.0 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Spt4 PF06093.13 CAR26349.1 - 5e-29 100.2 0.4 5.9e-29 100.0 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-TFIIB PF13453.6 CAR26349.1 - 0.042 13.2 0.5 0.076 12.4 0.5 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger TackOD1 PF18551.1 CAR26349.1 - 0.12 12.0 1.4 0.17 11.6 1.4 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 60KD_IMP PF02096.20 CAR26350.1 - 1.1e-08 35.1 4.0 2.5e-07 30.7 0.9 2.1 2 0 0 2 2 2 2 60Kd inner membrane protein DUF2462 PF09495.10 CAR26351.1 - 3.3e-15 56.6 11.8 3.3e-15 56.6 11.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) GATase_5 PF13507.6 CAR26352.1 - 6.3e-102 340.1 0.0 9.2e-102 339.6 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CAR26352.1 - 8e-44 149.5 0.0 1e-28 100.4 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CAR26352.1 - 6.2e-26 90.6 0.0 1.2e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CAR26352.1 - 8.3e-23 80.7 0.0 2.3e-22 79.3 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain EF-G-binding_N PF07299.11 CAR26352.1 - 0.13 12.8 0.1 0.67 10.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal FA_hydroxylase PF04116.13 CAR26353.1 - 1.7e-26 93.2 19.9 1.7e-26 93.2 19.9 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily PIN_4 PF13638.6 CAR26354.1 - 7.9e-06 26.2 0.0 1.3e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 PIN domain Septin PF00735.18 CAR26355.1 - 6.9e-89 297.9 0.1 1e-88 297.3 0.1 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CAR26355.1 - 0.00024 21.2 0.0 0.00096 19.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR26355.1 - 0.00036 20.5 0.1 0.0047 16.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CAR26355.1 - 0.00098 18.7 0.1 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain T2SSE PF00437.20 CAR26355.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Roc PF08477.13 CAR26355.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CAR26355.1 - 0.051 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 CAR26355.1 - 0.11 12.3 0.6 1.2 8.8 0.1 2.7 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 CAR26355.1 - 1.7 8.7 5.8 17 5.4 0.0 3.3 3 1 1 4 4 4 0 Dynamin family EF-hand_7 PF13499.6 CAR26356.1 - 1.4e-06 28.7 0.6 1.6e-05 25.2 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CAR26356.1 - 4e-05 23.2 0.2 0.097 12.7 0.0 3.7 3 1 1 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 CAR26356.1 - 0.0013 18.5 0.0 0.07 13.0 0.0 3.1 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CAR26356.1 - 0.0027 17.1 0.0 2.4 7.9 0.0 3.6 4 0 0 4 4 4 1 EF hand Suppressor_P21 PF11479.8 CAR26356.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain EF-hand_5 PF13202.6 CAR26356.1 - 0.1 12.2 0.0 20 4.9 0.0 3.3 3 0 0 3 3 3 0 EF hand IMUP PF15761.5 CAR26356.1 - 0.29 11.8 4.3 0.54 11.0 0.7 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Pkinase PF00069.25 CAR26357.1 - 1.9e-66 224.1 0.2 5.1e-59 199.8 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR26357.1 - 2.8e-48 164.5 0.3 7.2e-46 156.6 0.0 2.5 2 1 1 3 3 3 2 Protein tyrosine kinase Ras_bdg_2 PF14847.6 CAR26357.1 - 9.4e-36 122.2 0.1 2.3e-35 120.9 0.1 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 CAR26357.1 - 9.9e-11 41.6 0.0 3e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CAR26357.1 - 1.8e-09 37.9 0.1 4.6e-09 36.6 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 CAR26357.1 - 8.5e-05 22.5 0.0 0.00029 20.7 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 CAR26357.1 - 9.9e-05 21.8 0.0 0.0033 16.8 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CAR26357.1 - 0.00064 18.6 0.1 0.0016 17.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Metallophos PF00149.28 CAR26359.1 - 1.2e-16 61.9 2.6 1.6e-16 61.5 0.9 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase VPS38 PF17649.1 CAR26360.1 - 3.3e-167 556.7 8.1 3.7e-167 556.5 8.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 38 Jnk-SapK_ap_N PF09744.9 CAR26360.1 - 0.073 13.3 5.6 0.12 12.6 5.6 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 CAR26360.1 - 1.7 8.1 5.3 2.3 7.7 5.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Folliculin PF11704.8 CAR26361.1 - 8.3e-48 162.7 0.2 1.2e-47 162.2 0.2 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Lyase_1 PF00206.20 CAR26362.1 - 9.1e-26 91.0 0.0 1.6e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CAR26362.1 - 1.4e-17 64.0 0.0 5.5e-17 62.1 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 CAR26362.1 - 0.28 10.9 1.3 0.41 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) Bromodomain PF00439.25 CAR26363.1 - 7.3e-29 99.7 6.2 3e-15 56.1 0.5 2.9 3 0 0 3 3 3 2 Bromodomain BAH PF01426.18 CAR26363.1 - 3.2e-24 85.1 0.2 7.7e-24 83.9 0.1 1.7 2 0 0 2 2 2 1 BAH domain SIR2 PF02146.17 CAR26364.1 - 3.1e-35 121.7 0.0 6.6e-34 117.4 0.0 2.2 1 1 0 1 1 1 1 Sir2 family Meiosis_expr PF15163.6 CAR26364.1 - 0.016 15.9 0.0 0.035 14.8 0.0 1.5 1 0 0 1 1 1 0 Meiosis-expressed Glyco_transf_28 PF03033.20 CAR26364.1 - 0.072 13.1 0.0 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase family 28 N-terminal domain Zn-ribbon_8 PF09723.10 CAR26364.1 - 0.11 12.6 0.1 0.35 11.0 0.1 1.8 1 0 0 1 1 1 0 Zinc ribbon domain AA_permease_2 PF13520.6 CAR26365.1 - 3.5e-80 269.9 46.0 4.4e-80 269.6 46.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAR26365.1 - 1.4e-19 70.1 39.9 2.1e-19 69.5 39.9 1.2 1 0 0 1 1 1 1 Amino acid permease UPF0182 PF03699.13 CAR26365.1 - 0.35 8.9 5.7 0.5 8.4 5.7 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) eIF2A PF08662.11 CAR26366.1 - 1.7e-77 259.7 0.1 8.4e-77 257.4 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CAR26366.1 - 4.7e-05 24.1 0.4 0.37 11.8 0.1 4.2 3 1 0 3 3 3 2 WD domain, G-beta repeat MMU163 PF17119.5 CAR26367.1 - 6.8e-21 74.6 0.4 2.3e-20 72.8 0.4 1.7 1 1 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis IlvN PF07991.12 CAR26369.1 - 6.6e-45 152.6 0.0 9.4e-45 152.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 CAR26369.1 - 9.6e-41 139.4 0.0 2e-40 138.4 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 CAR26369.1 - 0.06 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PFK PF00365.20 CAR26370.1 - 1e-182 605.8 0.3 4e-102 341.4 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 CAR26370.1 - 2.7e-25 88.6 0.1 6.2e-25 87.5 0.1 1.7 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 CAR26370.1 - 0.034 13.8 0.1 0.23 11.1 0.0 2.4 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain TgMIC1 PF11476.8 CAR26370.1 - 0.069 12.9 0.9 0.53 10.0 0.0 2.4 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 ORF6C PF10552.9 CAR26372.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 ORF6C domain Dor1 PF04124.12 CAR26372.1 - 0.017 13.8 0.1 0.034 12.8 0.1 1.4 1 0 0 1 1 1 0 Dor1-like family Seryl_tRNA_N PF02403.22 CAR26372.1 - 0.044 14.0 0.5 0.11 12.7 0.3 1.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GlutR_dimer PF00745.20 CAR26372.1 - 0.067 13.6 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain BCAS2 PF05700.11 CAR26372.1 - 6 6.5 8.1 19 4.9 3.0 2.2 1 1 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) TDA11 PF17084.5 CAR26373.1 - 8.3e-60 203.0 46.6 2.9e-40 138.6 21.6 3.3 1 1 1 2 2 2 2 Topoisomerase I damage affected protein 11 EMC3_TMCO1 PF01956.16 CAR26373.1 - 5.5 6.7 6.2 12 5.6 6.2 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Spt20 PF12090.8 CAR26373.1 - 8.4 5.9 38.0 3.3 7.3 9.2 2.8 3 0 0 3 3 3 0 Spt20 family Kelch_4 PF13418.6 CAR26374.1 - 1.6e-30 104.8 5.8 6.4e-05 22.9 0.2 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 CAR26374.1 - 5.8e-30 103.0 4.1 2e-06 27.9 0.0 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CAR26374.1 - 1.7e-27 94.9 4.0 5.5e-05 23.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 CAR26374.1 - 1.7e-24 85.2 3.7 1.2e-05 25.4 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CAR26374.1 - 1.8e-19 69.0 1.9 2.6e-06 26.9 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CAR26374.1 - 2.2e-12 46.4 6.8 0.00035 20.4 0.0 5.9 6 1 0 6 6 6 3 Kelch motif Nmad5 PF18757.1 CAR26374.1 - 1.4 9.0 16.4 0.23 11.7 5.6 2.6 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 FUSC PF04632.12 CAR26374.1 - 2.9 6.3 7.3 1.7 7.1 5.1 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family Collagen PF01391.18 CAR26374.1 - 9 6.1 40.6 1.1 9.1 35.4 2.2 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) REC104 PF17378.2 CAR26375.1 - 0.00053 19.8 0.5 0.00087 19.1 0.2 1.6 1 1 0 1 1 1 1 Meiotic recombination protein REC104 Intron_maturas2 PF01348.21 CAR26376.1 - 2.8e-05 24.1 0.1 5.8e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Type II intron maturase DUF4724 PF15852.5 CAR26376.1 - 1.1 9.8 5.8 0.51 10.9 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) DUF3046 PF11248.8 CAR26377.1 - 0.17 12.3 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) ATP-synt_J PF04911.12 CAR26378.1 - 7.1e-26 89.5 2.8 8e-26 89.4 2.8 1.0 1 0 0 1 1 1 1 ATP synthase j chain Cys_Met_Meta_PP PF01053.20 CAR26379.1 - 2e-26 92.4 0.0 5.8e-26 90.9 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CAR26379.1 - 0.14 11.3 0.0 0.75 8.9 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II Glyco_hydro_47 PF01532.20 CAR26380.1 - 9.1e-150 499.5 0.2 1e-149 499.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Ctf8 PF09696.10 CAR26381.1 - 5.5e-18 65.7 0.2 1.4e-15 57.9 0.2 2.4 1 1 0 1 1 1 1 Ctf8 MIP-T3_C PF17749.1 CAR26381.1 - 0.093 12.7 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region zinc_ribbon_10 PF10058.9 CAR26382.1 - 1.5e-11 43.9 0.2 2.7e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein DUF3180 PF11377.8 CAR26382.1 - 0.01 15.9 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) HemX PF04375.14 CAR26382.1 - 0.037 13.3 13.6 0.031 13.6 5.7 2.0 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase AAA_13 PF13166.6 CAR26382.1 - 0.081 11.6 10.3 1.1 7.9 0.1 2.0 2 0 0 2 2 2 0 AAA domain Nmad5 PF18757.1 CAR26382.1 - 0.11 12.7 6.4 0.28 11.4 6.4 1.6 1 1 0 1 1 1 0 Nucleotide modification associated domain 5 PRTase_2 PF15609.6 CAR26382.1 - 0.13 11.8 0.5 0.31 10.5 0.5 1.7 1 1 0 1 1 1 0 Phosphoribosyl transferase Com_YlbF PF06133.11 CAR26382.1 - 0.32 11.6 17.8 3.2 8.4 4.4 3.1 2 1 1 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA HIP1_clath_bdg PF16515.5 CAR26382.1 - 0.35 11.5 16.1 0.44 11.2 0.6 2.7 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CorA PF01544.18 CAR26382.1 - 0.42 9.9 9.4 2.1 7.6 0.3 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Seryl_tRNA_N PF02403.22 CAR26382.1 - 0.57 10.4 14.0 2.8 8.2 0.1 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3573 PF12097.8 CAR26382.1 - 0.86 8.4 7.2 0.06 12.2 1.6 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3573) MHCassoc_trimer PF08831.10 CAR26382.1 - 1.1 9.3 5.8 0.33 11.0 1.5 2.2 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain DUF745 PF05335.13 CAR26382.1 - 1.4 8.6 7.4 0.69 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) LapA_dom PF06305.11 CAR26382.1 - 1.8 8.4 7.2 1.4 8.8 0.1 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain NPV_P10 PF05531.12 CAR26382.1 - 1.9 9.0 4.6 1.6 9.3 0.1 2.7 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.6 CAR26382.1 - 2 8.8 16.7 3.6 8.0 0.6 2.3 2 0 0 2 2 2 0 Syntaxin-like protein Spc24 PF08286.11 CAR26382.1 - 3 8.2 15.3 1.9 8.7 0.2 3.2 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF919 PF06034.11 CAR26382.1 - 3.2 7.7 10.8 3 7.7 0.6 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF919) PHM7_cyt PF14703.6 CAR26382.1 - 4 7.6 7.4 2.8 8.2 0.1 2.3 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter APG6_N PF17675.1 CAR26382.1 - 4.1 7.9 18.5 6.4 7.3 0.8 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region E2F_CC-MB PF16421.5 CAR26382.1 - 4.5 7.7 10.3 13 6.3 0.1 3.0 2 1 1 3 3 3 0 E2F transcription factor CC-MB domain FapA PF03961.13 CAR26382.1 - 5.8 5.4 11.1 7.8 5.0 0.3 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A LMBR1 PF04791.16 CAR26382.1 - 7.2 5.4 8.3 35 3.1 8.4 1.9 1 1 0 1 1 1 0 LMBR1-like membrane protein Phage_lysis PF03245.13 CAR26382.1 - 9.7 6.3 11.2 7.5 6.7 0.2 3.0 3 0 0 3 3 3 0 Bacteriophage Rz lysis protein NAC PF01849.18 CAR26383.1 - 7.1e-19 67.5 0.1 1.6e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 NAC domain MDM31_MDM32 PF08118.11 CAR26384.1 - 7.1e-223 741.0 4.3 7.9e-222 737.6 4.3 1.9 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins LAX PF15681.5 CAR26385.1 - 0.015 14.1 3.7 0.022 13.6 3.7 1.3 1 0 0 1 1 1 0 Lymphocyte activation family X SDP_N PF12278.8 CAR26385.1 - 0.14 12.3 4.1 0.31 11.2 4.1 1.6 1 0 0 1 1 1 0 Sex determination protein N terminal IBN_N PF03810.19 CAR26386.1 - 5e-14 52.0 0.0 1.9e-12 46.9 0.0 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain DUF5503 PF17607.2 CAR26386.1 - 0.097 13.0 0.2 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5503) Utp12 PF04003.12 CAR26387.1 - 0.0016 18.7 0.3 0.003 17.8 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CAR26387.1 - 0.033 14.5 0.3 13 6.1 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain TMF_TATA_bd PF12325.8 CAR26388.1 - 2e-32 111.8 21.6 2e-32 111.8 21.6 6.3 3 1 4 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CAR26388.1 - 9.3e-19 67.2 8.4 9.3e-19 67.2 8.4 10.1 5 4 5 10 10 10 2 TATA element modulatory factor 1 DNA binding SIKE PF05769.11 CAR26388.1 - 0.00073 19.5 6.7 0.00073 19.5 6.7 5.3 3 2 2 5 5 5 1 SIKE family Lebercilin PF15619.6 CAR26388.1 - 0.0017 18.1 18.7 0.0017 18.1 18.7 5.2 2 1 1 4 4 4 1 Ciliary protein causing Leber congenital amaurosis disease BST2 PF16716.5 CAR26388.1 - 0.0039 17.7 13.5 0.0039 17.7 13.5 7.5 2 2 6 9 9 9 1 Bone marrow stromal antigen 2 Csm1_N PF18504.1 CAR26388.1 - 0.021 15.1 6.5 0.021 15.1 6.5 9.7 5 3 6 11 11 11 0 Csm1 N-terminal domain Translat_reg PF01818.17 CAR26388.1 - 0.024 14.6 1.0 0.63 10.0 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage translational regulator DUF1664 PF07889.12 CAR26388.1 - 1.6 8.8 49.7 0.55 10.3 9.7 5.9 2 2 5 7 7 7 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 CAR26388.1 - 2.1 8.7 24.2 1 9.6 3.5 5.6 4 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Filament PF00038.21 CAR26388.1 - 4.6 6.7 82.8 0.015 14.9 39.9 4.7 2 2 2 4 4 4 0 Intermediate filament protein RIX1 PF08167.12 CAR26389.1 - 2.2e-47 161.3 4.8 2.2e-47 161.3 4.8 3.1 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis TLP-20 PF06088.11 CAR26389.1 - 1.2 9.0 7.1 0.055 13.4 1.1 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Transposase_21 PF02992.14 CAR26390.1 - 0.031 13.5 0.0 0.87 8.8 0.0 2.2 1 1 0 1 1 1 0 Transposase family tnp2 AAR2 PF05282.11 CAR26390.1 - 0.056 12.9 1.1 0.085 12.2 1.1 1.2 1 0 0 1 1 1 0 AAR2 protein Glutaredoxin2_C PF04399.13 CAR26390.1 - 0.074 12.9 0.3 0.19 11.6 0.3 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain zf-Tim10_DDP PF02953.15 CAR26391.1 - 4.2e-21 74.3 4.3 5.2e-21 74.1 4.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Peptidase_S9_N PF02897.15 CAR26391.1 - 0.043 12.6 0.4 0.053 12.3 0.4 1.0 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF445 PF04286.12 CAR26391.1 - 0.063 13.1 0.1 0.071 12.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Tti2 PF10521.9 CAR26392.1 - 1.3e-66 225.0 0.3 1.7e-66 224.7 0.3 1.1 1 0 0 1 1 1 1 Tti2 family Vpu PF00558.19 CAR26392.1 - 0.062 13.1 0.1 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Vpu protein Chalcone_2 PF16035.5 CAR26393.1 - 2.1e-69 233.4 0.0 2.7e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 CAR26393.1 - 0.011 15.9 0.5 0.19 11.9 0.1 2.1 1 1 0 2 2 2 0 Chalcone isomerase-like NIR_SIR PF01077.22 CAR26394.1 - 4e-51 172.7 0.0 1.1e-44 151.8 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 CAR26394.1 - 1.1e-27 95.7 0.0 8.3e-14 51.2 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 CAR26394.1 - 3.3e-26 92.2 0.0 7.7e-26 91.0 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin VWA_2 PF13519.6 CAR26396.1 - 8.2e-19 68.2 2.5 9e-19 68.1 0.0 2.2 2 1 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 CAR26396.1 - 2e-07 31.0 0.3 3e-07 30.5 0.3 1.2 1 0 0 1 1 1 1 Ssl1-like PDH PF02153.17 CAR26396.1 - 0.047 12.7 0.1 0.068 12.2 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Presenilin PF01080.17 CAR26396.1 - 0.24 10.1 0.8 0.26 10.0 0.8 1.2 1 0 0 1 1 1 0 Presenilin HNOBA PF07701.14 CAR26396.1 - 0.39 10.1 0.0 0.39 10.1 0.0 2.3 2 0 0 2 2 2 0 Heme NO binding associated IML1 PF12257.8 CAR26397.1 - 6.4e-104 347.1 0.3 1.1e-103 346.3 0.3 1.4 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 CAR26397.1 - 1.7e-26 92.1 0.1 3.9e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Homoserine_dh PF00742.19 CAR26398.1 - 1.9e-55 187.4 0.0 2.5e-55 187.1 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CAR26398.1 - 3.7e-22 79.2 0.0 6.6e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CAR26398.1 - 0.035 14.7 0.0 0.12 13.0 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 CAR26398.1 - 0.096 13.0 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 CAR26398.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HECT_2 PF09814.9 CAR26400.1 - 1.5e-62 211.6 0.1 1.8e-62 211.4 0.1 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding PknG_rubred PF16919.5 CAR26400.1 - 0.21 11.8 0.1 0.39 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein kinase G rubredoxin domain DHHA2 PF02833.14 CAR26401.1 - 2e-31 109.1 0.2 3.9e-31 108.2 0.2 1.5 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 CAR26401.1 - 1.2e-09 38.3 0.0 8.1e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 DHH family DUF4743 PF15916.5 CAR26402.1 - 5.4e-09 36.1 0.0 1.1e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 CAR26402.1 - 1.3e-06 28.5 0.0 5.5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain PMT PF02366.18 CAR26403.1 - 1.3e-78 263.9 20.5 1.3e-78 263.9 20.5 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CAR26403.1 - 1.8e-62 210.5 9.8 1.8e-62 210.5 9.8 2.6 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CAR26403.1 - 2.1e-22 79.9 0.0 3.8e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 MIR domain Herpes_UL43 PF05072.13 CAR26403.1 - 0.00027 20.2 1.8 0.0004 19.6 1.8 1.2 1 0 0 1 1 1 1 Herpesvirus UL43 protein Mgm101p PF06420.12 CAR26404.1 - 5.7e-85 283.1 0.0 6.7e-85 282.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Lac_bphage_repr PF06543.12 CAR26404.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor WD40 PF00400.32 CAR26405.1 - 7e-05 23.5 0.2 0.23 12.4 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat BPL_LplA_LipB PF03099.19 CAR26406.1 - 2.6e-08 33.8 0.1 9.5e-08 32.0 0.1 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family UPF0086 PF01868.16 CAR26407.1 - 1.7e-21 75.9 0.0 3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DUF268 PF03269.14 CAR26407.1 - 0.091 12.6 0.0 0.29 11.0 0.0 1.7 1 1 1 2 2 2 0 Caenorhabditis protein of unknown function, DUF268 COMPASS-Shg1 PF05205.12 CAR26408.1 - 3.6e-23 82.2 2.1 4.2e-23 82.0 2.1 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Coat_F PF07875.12 CAR26409.1 - 0.013 15.7 0.2 0.044 14.0 0.2 1.8 1 0 0 1 1 1 0 Coat F domain Cullin_Nedd8 PF10557.9 CAR26410.1 - 0.012 15.6 0.0 0.062 13.4 0.0 2.2 1 0 0 1 1 1 0 Cullin protein neddylation domain HTH_5 PF01022.20 CAR26410.1 - 0.081 12.8 0.0 0.23 11.4 0.0 1.8 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family RhoGAP PF00620.27 CAR26411.1 - 7.3e-40 136.3 0.7 5.3e-39 133.5 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 CAR26411.1 - 2.7e-05 24.3 4.7 0.00034 20.9 4.7 2.7 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Sec34 PF04136.15 CAR26411.1 - 0.21 11.5 7.1 0.097 12.6 3.4 2.3 2 1 0 2 2 2 0 Sec34-like family M11L PF11099.8 CAR26411.1 - 0.67 10.2 4.7 1.5 9.1 0.2 2.8 3 0 0 3 3 3 0 Apoptosis regulator M11L like Methyltransf_PK PF05891.12 CAR26412.1 - 1.8e-93 312.1 0.0 2e-93 311.9 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CAR26412.1 - 5.8e-07 30.1 0.0 1e-06 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR26412.1 - 0.00015 21.7 0.0 0.00049 20.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR26412.1 - 0.0014 19.2 0.0 0.0027 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CAR26412.1 - 0.012 14.9 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CAR26412.1 - 0.014 16.1 0.0 0.026 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Bin3 PF06859.12 CAR26412.1 - 0.035 14.8 0.0 0.12 13.1 0.0 1.6 1 1 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Methyltransf_2 PF00891.18 CAR26412.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.4 1 1 0 1 1 1 0 O-methyltransferase domain AIM5 PF17050.5 CAR26413.1 - 2e-07 31.7 0.0 2.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 SHMT PF00464.19 CAR26414.1 - 1.2e-204 679.5 0.0 1.4e-204 679.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CAR26414.1 - 0.0035 16.7 0.0 0.007 15.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Ras PF00071.22 CAR26415.1 - 2.5e-41 141.0 0.1 2.8e-40 137.6 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CAR26415.1 - 6.2e-33 113.6 0.0 9.4e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR26415.1 - 8.9e-17 61.1 0.0 2.7e-16 59.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR26415.1 - 3.6e-06 27.0 0.1 5.6e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CAR26415.1 - 3.8e-05 23.2 0.0 0.00012 21.6 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CAR26415.1 - 7.5e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CAR26415.1 - 0.0015 18.5 0.5 0.17 11.8 0.1 2.9 2 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CAR26415.1 - 0.0017 18.0 0.0 0.042 13.4 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 CAR26415.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 CAR26415.1 - 0.03 13.5 0.0 3.1 6.9 0.1 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 CAR26415.1 - 0.053 13.2 0.1 0.17 11.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain Rif1_N PF12231.8 CAR26416.1 - 5e-48 164.0 10.2 5e-48 164.0 10.2 1.7 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.25 CAR26417.1 - 9e-57 192.4 0.0 1.1e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR26417.1 - 6.1e-31 107.6 0.0 8e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR26417.1 - 2.1e-06 27.3 0.0 3.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAR26417.1 - 0.00029 19.7 0.0 0.00042 19.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CAR26417.1 - 0.0028 16.8 0.0 0.0058 15.7 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 CAR26417.1 - 0.07 12.1 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain UBX PF00789.20 CAR26418.1 - 1.1e-17 64.0 0.0 2.7e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 UBX domain DUF5526 PF17664.1 CAR26418.1 - 0.001 18.6 2.5 0.0023 17.5 2.5 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5526) 4HB_MCP_1 PF12729.7 CAR26418.1 - 0.0058 16.2 0.9 0.011 15.3 0.9 1.3 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction Snf7 PF03357.21 CAR26419.1 - 5.4e-16 58.7 17.2 8e-16 58.1 17.2 1.2 1 0 0 1 1 1 1 Snf7 Retrotran_gag_2 PF14223.6 CAR26419.1 - 0.24 11.0 6.7 0.44 10.2 2.6 2.4 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RPW8 PF05659.11 CAR26419.1 - 9.4 5.9 11.5 3.2 7.5 7.1 2.4 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Vps26 PF03643.15 CAR26420.1 - 1.1e-111 372.3 0.3 1.3e-111 372.1 0.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CAR26420.1 - 0.0021 18.1 0.2 0.041 13.9 0.2 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CAR26420.1 - 0.011 16.2 0.1 0.036 14.5 0.0 1.9 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Imm19 PF15563.6 CAR26420.1 - 0.08 12.4 0.5 0.19 11.2 0.5 1.5 1 1 0 1 1 1 0 Immunity protein 19 Rgp1 PF08737.10 CAR26420.1 - 0.08 12.1 0.5 1.4 8.0 0.1 2.4 2 1 0 2 2 2 0 Rgp1 ECSCR PF15820.5 CAR26421.1 - 0.091 12.6 2.3 0.11 12.3 0.4 2.2 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator rRNA_proc-arch PF13234.6 CAR26422.1 - 8.9e-83 278.3 0.5 8.9e-83 278.3 0.5 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 CAR26422.1 - 1.7e-53 180.6 0.5 4.7e-53 179.2 0.5 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CAR26422.1 - 9.8e-19 67.8 0.1 2.8e-17 63.0 0.0 3.0 3 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR26422.1 - 4.4e-06 27.0 0.0 4.2e-05 23.9 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ATPase_2 PF01637.18 CAR26422.1 - 0.026 14.5 1.4 4.4 7.2 0.0 2.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 CAR26422.1 - 0.087 13.1 0.0 0.35 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain HSM3_N PF18795.1 CAR26423.1 - 2.4e-113 377.4 13.7 3.7e-113 376.8 13.7 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, N terminal domain HSM3_C PF18794.1 CAR26423.1 - 2.1e-84 281.5 5.1 4.4e-84 280.5 5.1 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, C terminal domain Aminotran_1_2 PF00155.21 CAR26424.1 - 7.8e-79 265.5 0.0 8.9e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ING PF12998.7 CAR26425.1 - 9.6e-25 87.1 1.8 6e-24 84.6 1.1 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CAR26425.1 - 0.00022 21.1 9.3 0.00039 20.3 9.3 1.4 1 0 0 1 1 1 1 PHD-finger Med16 PF11635.8 CAR26425.1 - 0.0068 14.4 0.2 0.0073 14.3 0.2 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 zf-HC5HC2H PF13771.6 CAR26425.1 - 0.076 13.3 1.5 0.17 12.1 1.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Ras PF00071.22 CAR26426.1 - 2.3e-56 189.9 0.2 3e-56 189.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR26426.1 - 1e-20 74.1 0.0 1.7e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR26426.1 - 2.6e-09 36.8 0.1 3.1e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CAR26426.1 - 0.00094 19.1 1.0 1.1 9.1 0.2 2.6 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 CAR26426.1 - 0.0018 18.3 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR26426.1 - 0.0024 17.5 0.2 0.019 14.5 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 CAR26426.1 - 0.033 14.2 0.2 0.14 12.2 0.2 2.0 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DAD PF02109.16 CAR26427.1 - 1.9e-36 124.7 3.2 2.3e-36 124.4 3.2 1.1 1 0 0 1 1 1 1 DAD family PalH PF08733.10 CAR26427.1 - 2e-05 23.8 0.7 2.3e-05 23.6 0.7 1.0 1 0 0 1 1 1 1 PalH/RIM21 DUF4231 PF14015.6 CAR26427.1 - 0.07 13.6 0.1 0.098 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF2207 PF09972.9 CAR26427.1 - 0.14 10.9 0.1 0.17 10.6 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Y_phosphatase2 PF03162.13 CAR26428.1 - 2.5e-58 196.3 0.0 3.5e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CAR26428.1 - 1.6e-05 25.0 0.0 4.9e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CAR26428.1 - 0.039 13.8 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR26428.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ApoO PF09769.9 CAR26430.1 - 2.1e-07 31.0 0.1 0.032 14.2 0.0 3.0 2 1 1 3 3 3 2 Apolipoprotein O HEPN_LA2681 PF18733.1 CAR26430.1 - 0.016 14.5 0.1 0.027 13.8 0.1 1.4 1 0 0 1 1 1 0 LA2681-like HEPN Aa_trans PF01490.18 CAR26431.1 - 1.2e-96 323.9 34.8 1.5e-96 323.6 34.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DNA_pol_B PF00136.21 CAR26433.1 - 1e-119 400.3 0.2 1.5e-119 399.7 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CAR26433.1 - 1.5e-60 204.1 5.7 3e-60 203.1 5.7 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 CAR26433.1 - 1.5e-41 142.7 0.0 5.3e-41 140.9 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 CAR26433.1 - 2.3e-16 59.6 8.4 7e-16 58.1 8.4 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal CAF20 PF17052.5 CAR26433.1 - 0.24 11.6 4.8 0.91 9.7 4.8 2.0 1 0 0 1 1 1 0 Cap associated factor zinc_ribbon_4 PF13717.6 CAR26433.1 - 0.36 10.8 3.7 16 5.5 0.4 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.6 CAR26433.1 - 3.4 7.5 5.3 30 4.5 5.3 2.5 1 1 0 1 1 1 0 zinc-ribbon domain SNARE PF05739.19 CAR26434.1 - 1.5e-10 40.9 1.8 1.5e-10 40.9 1.8 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 CAR26434.1 - 2.8e-09 37.2 0.8 2.8e-09 37.2 0.8 3.1 3 0 0 3 3 3 2 Syntaxin-like protein Synaptobrevin PF00957.21 CAR26434.1 - 0.00044 20.0 2.6 0.00044 20.0 2.6 2.1 2 0 0 2 2 2 1 Synaptobrevin Rx_N PF18052.1 CAR26434.1 - 0.0073 16.6 0.1 0.0073 16.6 0.1 3.1 4 0 0 4 4 4 1 Rx N-terminal domain DUF5345 PF17280.2 CAR26434.1 - 0.032 14.2 10.2 0.058 13.4 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5345) T2SSF PF00482.23 CAR26434.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.6 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein F PepSY_TM PF03929.16 CAR26434.1 - 0.29 10.8 0.2 0.39 10.3 0.2 1.2 1 0 0 1 1 1 0 PepSY-associated TM region VIT1 PF01988.19 CAR26434.1 - 0.3 10.9 1.0 0.64 9.8 1.0 1.6 1 0 0 1 1 1 0 VIT family MCU PF04678.13 CAR26434.1 - 5 7.2 14.7 0.042 14.0 2.6 2.7 2 1 1 3 3 3 0 Mitochondrial calcium uniporter CRA PF06589.11 CAR26434.1 - 7.6 6.7 11.1 31 4.7 7.3 3.0 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) bZIP_2 PF07716.15 CAR26435.1 - 0.0017 18.4 4.8 0.0017 18.4 4.8 3.1 3 0 0 3 3 3 1 Basic region leucine zipper Optomotor-blind PF11078.8 CAR26435.1 - 0.77 10.4 3.8 7.1 7.3 0.1 2.4 2 0 0 2 2 2 0 Optomotor-blind protein N-terminal region RGS PF00615.19 CAR26436.1 - 3.1e-13 50.0 1.4 3.1e-13 50.0 1.4 1.6 2 0 0 2 2 2 1 Regulator of G protein signaling domain Myb_DNA-bind_2 PF08914.11 CAR26436.1 - 0.03 14.5 0.8 0.19 11.9 0.6 2.2 2 0 0 2 2 2 0 Rap1 Myb domain HMGL-like PF00682.19 CAR26437.1 - 5.8e-89 298.2 0.0 7.5e-89 297.8 0.0 1.1 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 CAR26437.1 - 5.4e-25 87.8 0.0 1.1e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Sigma_reg_N PF13800.6 CAR26437.1 - 0.18 12.1 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Syja_N PF02383.18 CAR26438.1 - 2.5e-75 253.8 0.2 5.2e-75 252.7 0.2 1.5 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CAR26438.1 - 9e-15 54.8 0.0 1.4e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YkuD PF03734.14 CAR26438.1 - 0.098 13.1 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain YEATS PF03366.16 CAR26439.1 - 1.7e-35 120.8 1.5 2.8e-35 120.1 1.5 1.4 1 0 0 1 1 1 1 YEATS family Lge1 PF11488.8 CAR26439.1 - 0.24 11.6 2.2 0.38 11.0 1.8 1.6 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 TFIIIC_sub6 PF10419.9 CAR26440.1 - 2.8e-24 84.8 0.1 5.9e-24 83.8 0.1 1.6 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain His_Phos_1 PF00300.22 CAR26440.1 - 1.1e-18 67.7 0.0 2.6e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Maf PF02545.14 CAR26441.1 - 2.8e-38 131.4 0.0 3.3e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein RRM_1 PF00076.22 CAR26442.1 - 3.4e-19 68.4 0.8 5.1e-19 67.9 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CAR26442.1 - 0.012 15.6 0.3 0.046 13.7 0.1 2.1 2 1 0 2 2 2 0 RL domain Limkain-b1 PF11608.8 CAR26442.1 - 0.03 14.4 1.0 0.45 10.6 0.0 2.8 2 1 1 3 3 3 0 Limkain b1 Cyt-b5 PF00173.28 CAR26443.1 - 4.5e-25 87.6 0.1 8.9e-25 86.6 0.1 1.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Cnd1 PF12717.7 CAR26444.1 - 0.00083 19.4 2.5 0.44 10.6 0.2 2.5 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CAR26444.1 - 0.0009 18.9 0.2 0.074 12.6 0.0 2.6 1 1 2 3 3 3 1 CLASP N terminal HEAT PF02985.22 CAR26444.1 - 0.09 13.1 0.0 62 4.3 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat MPDZ_u10 PF16667.5 CAR26444.1 - 4.8 8.2 11.4 6.9 7.6 9.0 2.5 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein DEAD PF00270.29 CAR26445.1 - 1.6e-49 168.0 0.0 2.1e-48 164.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR26445.1 - 5e-33 113.8 0.0 3.3e-32 111.1 0.0 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR26445.1 - 4.6e-05 23.5 0.0 0.00012 22.2 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 CAR26445.1 - 0.0015 17.4 0.0 0.029 13.2 0.0 2.1 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_30 PF13604.6 CAR26445.1 - 0.041 13.6 0.0 0.22 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF5335 PF17269.2 CAR26445.1 - 0.054 13.3 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) ERCC3_RAD25_C PF16203.5 CAR26445.1 - 0.081 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 CAR26445.1 - 0.11 12.8 0.0 11 6.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain GRP PF07172.11 CAR26445.1 - 6.1 7.6 45.1 1.2 9.8 27.3 2.5 2 0 0 2 2 2 0 Glycine rich protein family RNA_pol_L_2 PF13656.6 CAR26446.1 - 2.9e-34 116.7 0.0 3.8e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CAR26446.1 - 2.4e-14 52.5 0.0 3.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GST_N_2 PF13409.6 CAR26447.1 - 7.8e-21 74.2 0.0 6.7e-20 71.2 0.0 2.5 3 1 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CAR26447.1 - 8.5e-12 44.9 0.0 1.8e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CAR26447.1 - 0.005 17.0 0.2 0.015 15.5 0.2 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CAR26447.1 - 0.028 14.8 0.2 4.3 7.8 0.0 2.8 3 0 0 3 3 3 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CAR26447.1 - 0.045 14.0 0.4 0.28 11.4 0.4 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2854 PF11016.8 CAR26448.1 - 0.031 14.2 0.2 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) NOC3p PF07540.11 CAR26450.1 - 4.6e-29 100.7 0.0 4.6e-29 100.7 0.0 3.7 3 1 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 CAR26450.1 - 6.2e-25 88.2 0.0 6.2e-25 88.2 0.0 2.8 3 0 0 3 3 3 1 CBF/Mak21 family DUF4806 PF16064.5 CAR26450.1 - 0.045 14.0 1.5 0.12 12.7 0.5 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4806) DUF5308 PF17233.2 CAR26450.1 - 0.28 11.4 2.8 15 5.8 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5308) DUF489 PF04356.12 CAR26450.1 - 0.4 10.7 2.6 0.94 9.5 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Eapp_C PF10238.9 CAR26450.1 - 8.9 6.4 13.6 14 5.7 4.8 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein Mpp10 PF04006.12 CAR26451.1 - 1.2e-144 483.1 90.0 8.4e-144 480.3 90.0 1.8 1 1 0 1 1 1 1 Mpp10 protein Aa_trans PF01490.18 CAR26452.1 - 4.9e-81 272.5 19.1 5.8e-81 272.3 19.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Slx4 PF09494.10 CAR26452.1 - 0.08 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Slx4 endonuclease Fasciclin PF02469.22 CAR26453.1 - 5.7e-22 78.3 0.0 8.1e-06 26.1 0.0 5.8 5 1 0 5 5 5 4 Fasciclin domain Dynamin_M PF01031.20 CAR26454.1 - 6.3e-108 360.3 0.0 1.2e-107 359.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CAR26454.1 - 2.3e-54 184.0 0.0 9.8e-54 181.9 0.0 2.2 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CAR26454.1 - 6.5e-30 103.1 3.6 1.9e-29 101.6 3.6 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CAR26454.1 - 1.7e-05 24.9 0.4 0.00021 21.3 0.4 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 CAR26454.1 - 0.061 13.1 0.5 0.17 11.6 0.0 2.0 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system HAT_KAT11 PF08214.11 CAR26455.1 - 5.1e-97 325.3 0.8 6e-97 325.1 0.8 1.0 1 0 0 1 1 1 1 Histone acetylation protein Proteasome PF00227.26 CAR26456.1 - 2.7e-47 160.7 1.1 3e-47 160.6 1.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Sfi1_C PF10638.9 CAR26457.1 - 4.5e-41 139.9 6.7 1.6e-40 138.1 6.7 2.0 1 0 0 1 1 1 1 Spindle body associated protein C-terminus Sfi1 PF08457.10 CAR26457.1 - 4.9e-40 137.6 74.2 1.6e-37 129.3 52.2 3.2 1 1 2 3 3 3 3 Sfi1 spindle body protein Ribophorin_I PF04597.14 CAR26458.1 - 1.1e-118 397.3 0.4 1.2e-118 397.1 0.4 1.0 1 0 0 1 1 1 1 Ribophorin I CLP1_N PF16573.5 CAR26458.1 - 0.0033 17.6 0.0 6.4 7.1 0.0 3.1 3 1 0 3 3 3 2 N-terminal beta-sandwich domain of polyadenylation factor ORC_WH_C PF18137.1 CAR26459.1 - 1.9e-20 73.4 0.0 4.1e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 CAR26459.1 - 3.9e-06 26.2 2.3 8.3e-06 25.1 1.0 2.0 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus COX16 PF14138.6 CAR26460.1 - 8.2e-28 96.7 0.5 1.2e-27 96.2 0.0 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 MFS_1 PF07690.16 CAR26460.1 - 0.028 13.4 0.0 0.036 13.0 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily RSN1_7TM PF02714.15 CAR26461.1 - 5.9e-79 265.2 24.6 5.9e-79 265.2 24.6 3.4 5 0 0 5 5 5 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CAR26461.1 - 1.3e-26 93.2 7.3 1.3e-26 93.2 7.3 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CAR26461.1 - 3.2e-07 30.8 1.7 8.6e-07 29.3 1.7 1.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter MMM1 PF10296.9 CAR26462.1 - 9.4e-141 468.6 1.4 1.1e-140 468.4 1.4 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 CRR7 PF12095.8 CAR26462.1 - 0.12 12.8 1.1 3.7 8.1 0.0 2.9 4 0 0 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 PH_12 PF16457.5 CAR26463.1 - 1.6e-07 31.9 0.0 3.5e-06 27.6 0.0 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain MKRN1_C PF15815.5 CAR26463.1 - 2.3 8.7 5.7 11 6.4 0.1 3.5 4 0 0 4 4 4 0 E3 ubiquitin-protein ligase makorin-1, C-terminal DEAD PF00270.29 CAR26464.1 - 2.5e-47 160.9 0.1 5.1e-47 159.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR26464.1 - 4.9e-30 104.1 0.1 3.1e-28 98.3 0.0 3.1 2 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CAR26464.1 - 0.2 12.0 1.0 0.43 10.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain VIT1 PF01988.19 CAR26464.1 - 1.1 9.1 4.9 1.2 9.0 0.1 2.8 2 0 0 2 2 2 0 VIT family SYS1 PF09801.9 CAR26465.1 - 1.3e-49 168.0 16.3 1.5e-49 167.8 16.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network CTP_transf_1 PF01148.20 CAR26465.1 - 1.1 9.0 12.1 1.3 8.7 12.1 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family PP2C PF00481.21 CAR26466.1 - 8.4e-50 169.8 0.0 1.9e-49 168.7 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 CAR26466.1 - 4.6e-40 135.2 71.1 1.4e-10 40.8 3.2 9.8 6 3 3 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 CAR26466.1 - 1.8e-29 101.3 80.2 7.8e-05 23.0 3.2 11.8 7 2 4 12 12 12 11 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 CAR26466.1 - 1.3e-28 99.9 0.0 2.7e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 CAR26466.1 - 2.2e-10 40.3 25.5 0.0011 18.5 3.1 4.7 2 2 2 4 4 4 4 Leucine-rich repeat LRR_5 PF13306.6 CAR26466.1 - 2.8e-05 24.1 7.7 0.00015 21.7 1.0 3.3 3 0 0 3 3 3 1 BspA type Leucine rich repeat region (6 copies) Ad_cyc_g-alpha PF08509.11 CAR26466.1 - 0.0012 18.5 0.0 0.0037 16.9 0.0 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain PP2C_2 PF13672.6 CAR26466.1 - 0.01 15.5 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 Protein phosphatase 2C SUIM_assoc PF16619.5 CAR26466.1 - 6.8 6.8 0.0 6.8 6.8 0.0 6.5 3 3 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 LRR_2 PF07723.13 CAR26466.1 - 7.2 7.5 6.7 40 5.1 0.0 4.4 4 1 1 5 5 5 0 Leucine Rich Repeat PNP_UDP_1 PF01048.20 CAR26467.1 - 1.5e-34 119.3 0.0 1.9e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily NPCC PF08058.11 CAR26468.1 - 3.7e-28 98.2 0.5 6.2e-28 97.5 0.5 1.3 1 0 0 1 1 1 1 Nuclear pore complex component NAD_kinase PF01513.21 CAR26468.1 - 0.092 11.9 0.0 8.3 5.5 0.0 2.1 2 0 0 2 2 2 0 ATP-NAD kinase NIF PF03031.18 CAR26469.1 - 1e-52 178.1 0.0 1.8e-52 177.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sof1 PF04158.14 CAR26470.1 - 1.6e-28 98.8 11.4 4.3e-28 97.4 11.4 1.8 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 CAR26470.1 - 3.5e-27 94.1 12.3 5.8e-05 23.8 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR26470.1 - 2.8e-07 30.7 0.4 0.023 15.0 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CAR26470.1 - 0.00087 19.3 0.2 0.095 12.7 0.0 3.4 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 CAR26470.1 - 0.077 11.9 0.1 0.59 9.0 0.1 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Abhydro_lipase PF04083.16 CAR26471.1 - 1.7e-15 56.3 0.1 3.2e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CAR26471.1 - 1.3e-07 31.5 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR26471.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 POC3_POC4 PF10448.9 CAR26472.1 - 1.5e-31 109.4 0.0 1.6e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 SBDS PF01172.18 CAR26473.1 - 1.8e-35 120.9 2.3 3e-35 120.2 2.3 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CAR26473.1 - 1.1e-31 109.2 4.7 1.2e-31 109.1 1.6 2.0 2 0 0 2 2 2 1 SBDS protein C-terminal domain DASH_Dad1 PF08649.10 CAR26473.1 - 0.4 10.9 2.6 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad1 Phage_TAC_5 PF08890.11 CAR26473.1 - 0.51 10.3 6.2 0.23 11.5 0.2 2.9 1 1 2 3 3 3 0 Phage XkdN-like tail assembly chaperone protein, TAC HlyIII PF03006.20 CAR26474.1 - 5.3e-70 235.6 15.6 6.9e-70 235.3 15.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related TssN PF17555.2 CAR26474.1 - 0.12 11.8 11.0 0.12 11.8 9.6 1.6 1 1 1 2 2 2 0 Type VI secretion system, TssN CDC45 PF02724.14 CAR26474.1 - 0.99 7.6 5.0 1.2 7.4 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 CAR26474.1 - 4.4 6.5 10.1 9 5.5 10.1 1.4 1 0 0 1 1 1 0 NOA36 protein PUF PF00806.19 CAR26475.1 - 1.1e-54 179.1 9.0 2.5e-07 30.0 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SUIM_assoc PF16619.5 CAR26475.1 - 0.0032 17.5 2.6 0.0032 17.5 2.6 2.5 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Rab5ip PF07019.12 CAR26476.1 - 1.4e-23 83.3 4.9 1.6e-23 83.1 4.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF383 PF04063.14 CAR26477.1 - 2.9e-65 219.5 2.0 5.2e-65 218.7 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CAR26477.1 - 2.4e-23 81.7 0.1 6.8e-23 80.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) PapB PF03333.13 CAR26477.1 - 0.036 14.1 0.1 0.092 12.8 0.1 1.7 1 0 0 1 1 1 0 Adhesin biosynthesis transcription regulatory protein TFIIF_alpha PF05793.12 CAR26478.1 - 3.5e-10 39.1 0.4 3.5e-10 39.1 0.4 3.2 2 1 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TMEM214 PF10151.9 CAR26478.1 - 3.6 5.9 7.6 7.6 4.9 7.6 1.4 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator tRNA-synt_1b PF00579.25 CAR26479.1 - 1e-75 254.8 0.0 1.3e-75 254.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.20 CAR26480.1 - 7.3e-13 48.5 8.8 7.3e-13 48.5 8.8 2.6 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.24 CAR26480.1 - 5.7 7.2 12.6 1.6 8.9 8.0 2.6 2 0 0 2 2 2 0 B-box zinc finger zf-UBR PF02207.20 CAR26481.1 - 1.4e-15 57.2 15.7 1.4e-15 57.2 15.7 2.4 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CAR26481.1 - 0.00011 21.9 0.0 0.00038 20.2 0.0 2.0 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 CAR26481.1 - 0.00064 20.0 1.6 0.00064 20.0 1.6 3.6 4 0 0 4 4 4 1 Ring finger domain zf-rbx1 PF12678.7 CAR26481.1 - 0.0081 16.4 0.2 0.0081 16.4 0.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain UCR_UQCRX_QCR9 PF05365.12 CAR26482.1 - 1.7e-26 91.9 1.0 1.8e-26 91.8 1.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like T6SS_HCP PF05638.12 CAR26482.1 - 0.021 15.2 0.0 0.023 15.1 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion system effector, Hcp VASt PF16016.5 CAR26482.1 - 0.054 13.9 0.2 0.063 13.7 0.2 1.0 1 0 0 1 1 1 0 VAD1 Analog of StAR-related lipid transfer domain DUF2976 PF11190.8 CAR26482.1 - 0.13 12.1 0.1 0.15 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) zf-Tim10_DDP PF02953.15 CAR26483.1 - 9.2e-19 66.9 0.7 1.2e-18 66.5 0.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Clat_adaptor_s PF01217.20 CAR26484.1 - 4.7e-56 188.7 0.8 5.6e-56 188.4 0.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Orthopox_B11R PF07033.11 CAR26484.1 - 0.085 12.7 0.5 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 Orthopoxvirus B11R protein CBP4 PF07960.11 CAR26485.1 - 1.6e-56 189.7 4.0 2.1e-56 189.3 4.0 1.1 1 0 0 1 1 1 1 CBP4 mTERF PF02536.14 CAR26485.1 - 0.011 14.7 0.9 0.012 14.5 0.9 1.0 1 0 0 1 1 1 0 mTERF LAMTOR PF15454.6 CAR26485.1 - 0.051 14.2 0.6 0.051 14.2 0.6 2.7 2 1 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator VIT1 PF01988.19 CAR26485.1 - 7.2 6.4 5.6 3.7 7.3 1.6 1.9 2 0 0 2 2 2 0 VIT family SE PF08491.10 CAR26486.1 - 7.7e-121 402.4 0.0 1e-120 402.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CAR26486.1 - 7.6e-16 58.3 0.0 1.1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CAR26486.1 - 2.8e-07 30.4 0.1 0.00041 20.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 CAR26486.1 - 0.00044 20.7 0.7 0.0015 19.0 0.1 2.2 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAR26486.1 - 0.0031 17.7 0.1 0.0069 16.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CAR26486.1 - 0.0067 15.6 1.8 0.01 15.0 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CAR26486.1 - 0.008 15.4 0.2 0.02 14.2 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CAR26486.1 - 0.014 15.3 0.1 0.021 14.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CAR26486.1 - 0.019 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 CAR26486.1 - 0.034 14.7 0.1 0.067 13.8 0.1 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Thi4 PF01946.17 CAR26486.1 - 0.035 13.3 0.1 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 CAR26486.1 - 0.056 13.7 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.7 CAR26486.1 - 0.061 12.7 1.4 0.072 12.4 0.5 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase adh_short PF00106.25 CAR26486.1 - 0.18 11.2 0.1 0.43 10.0 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase Pyr_redox_3 PF13738.6 CAR26486.1 - 0.18 11.0 0.1 0.32 10.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAR26486.1 - 0.24 10.1 1.4 0.37 9.4 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 CAR26486.1 - 0.29 10.1 0.8 0.4 9.7 0.2 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-RRN7 PF11781.8 CAR26487.1 - 5.2e-10 38.8 5.4 4.6e-09 35.8 0.9 2.3 2 0 0 2 2 2 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 LsmAD PF06741.13 CAR26488.1 - 1.2e-28 99.5 1.1 1.2e-28 99.5 1.1 2.5 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 CAR26488.1 - 6.7e-16 58.2 0.0 1.7e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain CENP-Q PF13094.6 CAR26489.1 - 2.7e-07 31.0 3.6 2.7e-07 31.0 3.6 2.1 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit HEPN_MAE_28990 PF18737.1 CAR26489.1 - 0.0025 17.8 12.4 0.37 10.7 5.7 2.6 1 1 1 2 2 2 2 MAE_28990/MAE_18760-like HEPN Speriolin_C PF15059.6 CAR26489.1 - 0.017 15.2 0.9 0.042 14.0 0.3 2.0 1 1 1 2 2 2 0 Speriolin C-terminus DUF755 PF05501.11 CAR26489.1 - 0.074 13.3 2.2 0.2 12.0 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF755) UCH PF00443.29 CAR26490.1 - 2.4e-49 168.1 0.8 5.8e-49 166.9 0.8 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR26490.1 - 1.9e-06 27.7 6.2 6e-06 26.1 0.2 2.7 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Ndc1_Nup PF09531.10 CAR26490.1 - 0.85 8.2 5.7 0.82 8.3 3.7 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Aminotran_1_2 PF00155.21 CAR26492.1 - 1.1e-18 67.5 0.0 1.3e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CAR26492.1 - 3.3e-05 22.8 0.0 5.4e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase PET122 PF05476.11 CAR26493.1 - 1.9e-122 407.6 1.6 2.2e-122 407.4 1.6 1.0 1 0 0 1 1 1 1 PET122 COX6A PF02046.15 CAR26493.1 - 0.011 16.2 0.4 0.024 15.1 0.4 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa 60KD_IMP PF02096.20 CAR26494.1 - 8.8e-20 71.3 0.0 8.8e-20 71.3 0.0 1.5 2 0 0 2 2 2 1 60Kd inner membrane protein RhoGAP PF00620.27 CAR26495.1 - 8.3e-38 129.6 1.8 1.4e-37 128.9 0.2 2.2 2 0 0 2 2 2 1 RhoGAP domain RasGEF_N PF00618.20 CAR26495.1 - 6e-17 61.8 0.5 6e-17 61.8 0.5 4.1 4 0 0 4 4 4 1 RasGEF N-terminal motif RasGEF PF00617.19 CAR26495.1 - 1.9e-11 44.5 0.8 1.5e-09 38.3 0.0 3.7 3 1 0 3 3 3 1 RasGEF domain PH PF00169.29 CAR26495.1 - 0.013 16.0 0.0 0.087 13.3 0.0 2.6 1 0 0 1 1 1 0 PH domain UPF0160 PF03690.13 CAR26496.1 - 1.2e-131 439.1 0.0 1.4e-131 438.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF5060 PF16586.5 CAR26496.1 - 0.027 14.8 0.0 0.087 13.2 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5060) Pet100 PF09803.9 CAR26497.1 - 3.1e-10 40.4 0.6 4.3e-10 40.0 0.1 1.5 2 0 0 2 2 2 1 Pet100 Sec34 PF04136.15 CAR26498.1 - 4.7e-43 146.6 4.6 4.7e-43 146.6 4.6 3.8 3 1 0 3 3 3 1 Sec34-like family PLU-1 PF08429.11 CAR26498.1 - 0.021 14.0 8.9 0.17 11.0 2.9 3.2 2 2 0 2 2 2 0 PLU-1-like protein DUF5344 PF17279.2 CAR26498.1 - 0.11 13.1 7.6 0.88 10.2 0.4 4.6 3 1 0 3 3 3 0 Family of unknown function (DUF5344) GAT PF03127.14 CAR26498.1 - 0.17 12.2 11.3 0.51 10.7 0.1 4.6 3 1 1 4 4 4 0 GAT domain Ribosomal_S20p PF01649.18 CAR26498.1 - 0.74 10.5 6.2 6.1 7.6 0.0 4.2 4 0 0 4 4 4 0 Ribosomal protein S20 Tfb5 PF06331.12 CAR26499.1 - 1.8e-26 91.9 0.1 2e-26 91.7 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Clathrin PF00637.20 CAR26500.1 - 6.4e-26 90.9 2.0 6.4e-26 90.9 2.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.9 CAR26500.1 - 0.0014 18.9 0.1 0.0014 18.9 0.1 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.32 CAR26500.1 - 0.014 16.3 0.4 0.086 13.8 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat WD40_like PF17005.5 CAR26500.1 - 0.025 13.9 0.2 0.95 8.7 0.0 2.4 1 1 1 2 2 2 0 WD40-like domain RXT2_N PF08595.11 CAR26500.1 - 0.75 9.8 13.8 1.6 8.8 13.8 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 CAR26500.1 - 3 7.5 23.6 5.5 6.6 23.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 CAR26500.1 - 5 5.1 6.3 7.1 4.6 6.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DDE_1 PF03184.19 CAR26501.1 - 2e-66 222.9 2.0 2.1e-66 222.9 0.5 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CAR26501.1 - 1.1e-13 51.0 0.1 1.1e-13 51.0 0.1 2.4 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CAR26501.1 - 0.001 18.7 0.0 0.003 17.2 0.0 1.9 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 CAR26501.1 - 0.17 12.5 0.8 3.7 8.2 0.1 2.9 3 0 0 3 3 3 0 Homeodomain-like domain Mucin PF01456.17 CAR26501.1 - 7.9 6.5 14.1 18 5.3 14.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Transthyretin PF00576.21 CAR26502.1 - 1.1e-33 116.2 0.0 1.5e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family Stn1_C PF12659.7 CAR26503.1 - 3.8e-42 143.0 0.2 6.2e-42 142.3 0.2 1.3 1 0 0 1 1 1 1 Telomere capping C-terminal wHTH Stn1 PF10451.9 CAR26503.1 - 2.1e-34 118.7 0.9 2.9e-33 114.9 0.3 2.2 1 1 1 2 2 2 1 Telomere regulation protein Stn1 Methyltransf_8 PF05148.15 CAR26504.1 - 9.8e-67 225.0 1.7 2.5e-65 220.4 0.1 2.8 1 1 1 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CAR26504.1 - 1.8e-07 31.7 0.0 7.3e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR26504.1 - 0.00014 22.5 0.0 0.0024 18.6 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR26504.1 - 0.0098 15.7 2.0 0.54 10.0 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain GREB1 PF15782.5 CAR26504.1 - 0.082 10.0 2.8 1.6 5.8 5.8 1.5 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Methyltransf_32 PF13679.6 CAR26504.1 - 0.1 12.5 1.5 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Ndc1_Nup PF09531.10 CAR26504.1 - 1.8 7.1 5.6 2.1 6.9 5.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup YebO PF13974.6 CAR26504.1 - 4.8 7.3 7.1 18 5.5 7.1 2.0 1 0 0 1 1 1 0 YebO-like protein Presenilin PF01080.17 CAR26504.1 - 9.5 4.9 7.5 14 4.3 7.5 1.2 1 0 0 1 1 1 0 Presenilin DUF846 PF05832.12 CAR26505.1 - 4.3e-45 153.2 4.8 5.2e-45 152.9 4.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) FA_desaturase PF00487.24 CAR26505.1 - 1.9 8.2 8.9 0.12 12.1 2.8 1.8 1 1 1 2 2 2 0 Fatty acid desaturase CBFD_NFYB_HMF PF00808.23 CAR26507.1 - 2.5e-10 40.5 0.0 4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SecE PF00584.20 CAR26508.1 - 6.2e-13 48.5 0.1 7e-13 48.3 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex HBB PF06777.11 CAR26508.1 - 0.09 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Helical and beta-bridge domain Nop52 PF05997.12 CAR26509.1 - 1.1e-68 231.2 10.0 1.3e-68 231.0 10.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.8 CAR26509.1 - 0.14 12.3 1.9 1.2 9.3 0.0 2.7 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair Slu7 PF11708.8 CAR26510.1 - 4.2e-18 66.1 18.9 4.5e-16 59.4 18.8 2.3 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 CAR26510.1 - 0.0046 17.0 0.6 0.0082 16.2 0.6 1.4 1 0 0 1 1 1 1 Zinc knuckle PrpF PF04303.13 CAR26510.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 PrpF protein zf-CCHC_5 PF14787.6 CAR26510.1 - 0.54 10.0 3.3 1.1 9.0 3.3 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger SPT2 PF08243.11 CAR26511.1 - 1.3e-28 99.7 31.4 1.3e-28 99.7 31.4 2.3 2 1 1 3 3 3 1 SPT2 chromatin protein YebO PF13974.6 CAR26511.1 - 0.47 10.6 6.9 3.4 7.8 1.4 2.9 2 0 0 2 2 2 0 YebO-like protein Rad4 PF03835.15 CAR26512.1 - 1.9e-31 108.7 1.8 1.9e-31 108.7 1.8 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CAR26512.1 - 1.8e-23 82.7 0.2 4.2e-23 81.5 0.1 1.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CAR26512.1 - 1.3e-15 57.0 0.3 5.8e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CAR26512.1 - 1.3e-08 35.7 0.7 1.3e-08 35.7 0.7 3.6 4 1 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CAR26512.1 - 4.4e-05 23.9 0.1 0.00093 19.6 0.0 2.6 2 0 0 2 2 2 1 Transglutaminase-like superfamily ChaC PF04752.12 CAR26513.1 - 2e-57 194.1 0.0 2.5e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein ABC_tran PF00005.27 CAR26514.1 - 3.1e-37 128.1 0.0 3e-18 66.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 CAR26514.1 - 4.7e-15 55.1 5.6 1.2e-14 53.9 5.6 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 CAR26514.1 - 2.2e-11 44.1 7.1 0.025 14.4 0.1 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR26514.1 - 1.2e-10 41.2 1.9 0.0093 15.4 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 CAR26514.1 - 4.8e-07 29.3 4.0 4.8e-07 29.3 4.0 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_16 PF13191.6 CAR26514.1 - 3.9e-06 27.3 0.0 0.0054 17.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 CAR26514.1 - 7.4e-06 26.4 0.0 0.049 14.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CAR26514.1 - 7.6e-06 25.9 0.1 0.041 13.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CAR26514.1 - 2.4e-05 24.6 0.0 0.0078 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.7 CAR26514.1 - 4.2e-05 23.4 2.7 4.2e-05 23.4 2.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_23 PF13476.6 CAR26514.1 - 0.00017 22.1 0.0 0.032 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CAR26514.1 - 0.00023 21.1 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_29 PF13555.6 CAR26514.1 - 0.00026 20.7 1.1 0.52 10.1 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CAR26514.1 - 0.00066 19.5 5.5 0.33 10.6 0.3 3.1 2 2 0 3 3 3 2 AAA ATPase domain Fer4_7 PF12838.7 CAR26514.1 - 0.00089 19.8 8.1 0.0013 19.3 0.4 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_30 PF13604.6 CAR26514.1 - 0.0012 18.6 0.5 0.075 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.6 CAR26514.1 - 0.0018 18.3 11.3 0.0041 17.2 11.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain RNA_helicase PF00910.22 CAR26514.1 - 0.002 18.5 0.0 0.9 10.0 0.0 3.0 3 0 0 3 3 3 1 RNA helicase NB-ARC PF00931.22 CAR26514.1 - 0.0022 17.3 0.0 0.58 9.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_28 PF13521.6 CAR26514.1 - 0.0033 17.7 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CAR26514.1 - 0.0035 17.3 1.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 CAR26514.1 - 0.0036 17.1 0.9 0.58 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 CAR26514.1 - 0.0049 17.0 10.5 0.011 15.9 10.5 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_33 PF13671.6 CAR26514.1 - 0.0059 16.8 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_2 PF12797.7 CAR26514.1 - 0.0065 16.5 1.0 0.0065 16.5 1.0 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain SRP54 PF00448.22 CAR26514.1 - 0.0087 15.7 2.8 0.37 10.4 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_10 PF13237.6 CAR26514.1 - 0.009 16.1 1.5 0.009 16.1 1.5 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CAR26514.1 - 0.012 16.6 0.2 0.012 16.6 0.2 2.6 2 0 0 2 2 1 0 4Fe-4S double cluster binding domain AAA_7 PF12775.7 CAR26514.1 - 0.015 14.8 0.4 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Fer4_17 PF13534.6 CAR26514.1 - 0.017 15.6 0.1 0.017 15.6 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain MMR_HSR1 PF01926.23 CAR26514.1 - 0.021 14.9 0.1 4.5 7.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 CAR26514.1 - 0.021 14.8 1.1 0.24 11.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 CAR26514.1 - 0.027 13.8 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_18 PF13238.6 CAR26514.1 - 0.027 15.0 0.0 18 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CAR26514.1 - 0.04 13.9 0.0 9.2 6.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 CAR26514.1 - 0.053 13.5 0.1 0.69 9.9 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SbcCD_C PF13558.6 CAR26514.1 - 0.054 13.7 0.0 13 6.1 0.0 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 CAR26514.1 - 0.057 12.1 0.3 0.17 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.6 CAR26514.1 - 0.11 12.9 0.2 0.11 12.9 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain VirE PF05272.11 CAR26514.1 - 0.13 12.0 0.0 5.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E Septin PF00735.18 CAR26514.1 - 0.14 11.5 0.0 4.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Septin DLIC PF05783.11 CAR26514.1 - 0.16 10.8 0.1 0.31 9.8 0.1 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) MeaB PF03308.16 CAR26514.1 - 0.18 10.7 0.1 3.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_4 PF12800.7 CAR26514.1 - 0.32 11.6 15.3 0.29 11.7 3.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain NTPase_1 PF03266.15 CAR26514.1 - 0.58 10.1 1.9 8.8 6.2 0.1 3.0 3 0 0 3 3 3 0 NTPase Fer4_3 PF12798.7 CAR26514.1 - 3.3 8.9 16.8 0.13 13.3 4.5 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.23 CAR26515.1 - 3.2e-62 210.3 0.0 5.2e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cdh1_DBD_1 PF18196.1 CAR26515.1 - 1.2e-43 148.3 7.2 1.2e-43 148.3 7.2 2.6 2 0 0 2 2 2 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 CAR26515.1 - 4.4e-28 97.6 1.2 4.4e-28 97.6 1.2 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 CAR26515.1 - 5.3e-21 74.3 5.2 6.8e-13 48.3 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CAR26515.1 - 1e-20 74.1 0.0 2.9e-20 72.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR26515.1 - 1.8e-08 34.5 0.8 1.4e-07 31.7 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CAR26515.1 - 5.4e-07 29.1 0.1 2.6e-06 26.8 0.1 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SLIDE PF09111.10 CAR26515.1 - 0.0019 18.2 2.2 0.0046 17.0 0.1 2.8 3 0 0 3 3 3 1 SLIDE Myb_DNA-binding PF00249.31 CAR26515.1 - 0.0072 16.5 0.2 0.093 12.9 0.0 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain CHDCT2 PF08074.11 CAR26515.1 - 0.045 13.9 0.7 0.25 11.5 0.0 2.6 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain RRM_1 PF00076.22 CAR26516.1 - 1.6e-81 268.1 3.7 2.7e-20 72.0 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CAR26516.1 - 2.4e-18 66.1 2.1 1.7e-17 63.3 0.1 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 CAR26516.1 - 1.8e-07 30.9 0.0 0.00018 21.3 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 CAR26516.1 - 7.4e-06 25.9 6.0 1.1 9.4 0.0 4.9 5 0 0 5 5 5 2 RNA binding motif RRM_7 PF16367.5 CAR26516.1 - 4.4e-05 23.5 0.2 0.024 14.8 0.0 4.0 3 3 0 3 3 3 1 RNA recognition motif YflT PF11181.8 CAR26516.1 - 0.019 15.4 5.8 8 7.0 0.5 3.7 2 1 1 3 3 3 0 Heat induced stress protein YflT OB_RNB PF08206.11 CAR26516.1 - 0.025 14.3 5.4 1 9.1 0.5 3.7 3 1 0 3 3 3 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 CAR26516.1 - 0.14 12.1 0.3 18 5.4 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif UQ_con PF00179.26 CAR26517.1 - 3.8e-48 162.7 0.0 4.3e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAR26517.1 - 0.0014 18.3 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CAR26517.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 CAR26517.1 - 0.076 13.3 0.3 0.11 12.8 0.3 1.6 1 1 0 1 1 1 0 RWD domain PhoLip_ATPase_C PF16212.5 CAR26518.1 - 6.8e-79 265.1 26.4 6.8e-79 265.1 26.4 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAR26518.1 - 3e-17 62.1 1.3 3e-17 62.1 1.3 2.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CAR26518.1 - 1.8e-10 40.7 0.0 9e-10 38.5 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CAR26518.1 - 1.7e-08 35.0 0.5 0.00051 20.4 0.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CAR26518.1 - 0.00013 21.6 1.5 0.00022 20.8 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CAR26518.1 - 0.0034 17.2 0.1 0.0079 16.0 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PolyA_pol PF01743.20 CAR26520.1 - 1.4e-30 106.3 0.1 2.7e-30 105.4 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain tRNA_NucTran2_2 PF13735.6 CAR26520.1 - 0.00012 22.1 0.0 0.00032 20.7 0.0 1.7 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative PolyA_pol_RNAbd PF12627.7 CAR26520.1 - 0.00081 19.1 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A JmjC PF02373.22 CAR26521.1 - 1.2e-40 138.4 0.3 1.2e-40 138.4 0.3 2.1 2 0 0 2 2 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CAR26521.1 - 3e-15 55.9 0.8 1.3e-14 53.8 0.9 2.1 2 0 0 2 2 1 1 jmjN domain zf-H2C2_2 PF13465.6 CAR26521.1 - 2.2e-07 31.0 5.8 2.2e-07 31.0 5.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 CAR26521.1 - 2.8e-06 27.5 14.4 0.0019 18.6 1.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CAR26521.1 - 0.00037 20.4 5.6 0.00037 20.4 5.6 2.7 3 0 0 3 3 2 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CAR26521.1 - 0.00061 20.4 17.9 0.05 14.5 1.4 3.4 3 0 0 3 3 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CAR26521.1 - 0.0061 16.7 3.4 0.0061 16.7 3.4 1.8 2 0 0 2 2 1 1 Zinc ribbon domain zf_UBZ PF18439.1 CAR26521.1 - 0.026 14.1 2.7 2.5 7.7 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HypA PF01155.19 CAR26521.1 - 0.038 14.0 0.6 0.087 12.8 0.6 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_jaz PF12171.8 CAR26521.1 - 0.072 13.4 8.9 0.15 12.4 2.4 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DZR PF12773.7 CAR26521.1 - 0.085 12.9 0.5 0.2 11.7 0.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_8 PF15909.5 CAR26521.1 - 0.09 13.1 1.6 0.23 11.8 1.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc ribbon zinc_ribbon_5 PF13719.6 CAR26521.1 - 0.11 12.2 1.2 0.37 10.6 1.2 1.9 1 0 0 1 1 1 0 zinc-ribbon domain zf-MYST PF17772.1 CAR26521.1 - 0.39 10.4 1.5 0.58 9.8 0.1 2.0 2 0 0 2 2 2 0 MYST family zinc finger domain ADK_lid PF05191.14 CAR26521.1 - 0.52 10.3 3.6 22 5.2 3.4 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-met PF12874.7 CAR26521.1 - 1.1 9.7 7.1 4.3 7.9 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CAR26521.1 - 2.2 8.1 10.7 0.12 12.2 3.4 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type LIM PF00412.22 CAR26521.1 - 4.7 7.5 5.8 47 4.3 6.0 2.3 1 1 0 1 1 1 0 LIM domain zf_C2H2_ZHX PF18387.1 CAR26521.1 - 8.8 6.1 7.5 0.94 9.2 1.2 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain MutS_V PF00488.21 CAR26522.1 - 1.7e-64 217.3 0.9 3.5e-64 216.3 0.9 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAR26522.1 - 4.5e-34 118.3 0.4 4.5e-34 118.3 0.4 1.9 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CAR26522.1 - 3.9e-32 110.8 0.0 2.1e-31 108.5 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 CAR26522.1 - 6.8e-19 68.0 0.3 1.4e-18 67.0 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 CAR26522.1 - 3.4e-13 50.0 0.0 2.5e-12 47.3 0.0 2.3 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.6 CAR26522.1 - 0.045 13.5 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mitofilin PF09731.9 CAR26522.1 - 3.4 6.4 20.9 6.5 5.5 20.9 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ABC_tran PF00005.27 CAR26522.1 - 3.7 8.1 6.6 3.3 8.2 0.0 3.0 3 0 0 3 3 3 0 ABC transporter ADK PF00406.22 CAR26523.1 - 1.3e-41 142.2 0.0 1.6e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAR26523.1 - 1.1e-18 68.0 0.0 1.7e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CAR26523.1 - 2.1e-13 50.0 0.0 3.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CAR26523.1 - 0.0001 22.8 0.0 0.00017 22.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAR26523.1 - 0.0011 19.2 0.1 0.011 15.9 0.1 2.4 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CAR26523.1 - 0.11 11.8 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DEAD_2 PF06733.15 CAR26524.1 - 9.4e-57 191.5 3.6 1.5e-56 190.8 2.5 1.9 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 CAR26524.1 - 7.3e-44 149.9 0.0 2.1e-43 148.5 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 CAR26524.1 - 1.7e-43 148.5 3.0 3.4e-39 134.5 1.1 2.7 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 CAR26524.1 - 0.00086 19.3 0.1 0.029 14.4 0.1 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR26524.1 - 0.013 15.3 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase Sec63 PF02889.16 CAR26525.1 - 1.8e-133 443.5 13.1 3.4e-75 252.5 0.2 3.0 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 CAR26525.1 - 1.1e-44 152.3 0.0 1.6e-28 99.6 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CAR26525.1 - 1.1e-19 71.0 0.0 7e-13 48.9 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_PWI PF18149.1 CAR26525.1 - 3.1e-17 62.7 2.1 3.1e-17 62.7 2.1 3.3 3 0 0 3 3 3 1 N-terminal helicase PWI domain Helicase_C PF00271.31 CAR26525.1 - 2.5e-10 40.7 0.1 1.2e-07 32.1 0.0 4.0 3 2 0 3 3 2 1 Helicase conserved C-terminal domain Zeta_toxin PF06414.12 CAR26525.1 - 0.01 15.1 0.0 5.4 6.3 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin IstB_IS21 PF01695.17 CAR26525.1 - 0.017 14.9 0.0 1.3 8.7 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.29 CAR26525.1 - 0.032 14.6 0.8 0.43 11.0 0.0 3.3 4 1 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CAR26525.1 - 0.052 13.1 0.0 0.46 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain TRAP_alpha PF03896.16 CAR26525.1 - 0.68 9.1 7.1 1.4 8.0 7.1 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Pox_RNA_Pol_19 PF05320.12 CAR26525.1 - 0.94 9.4 8.6 3.1 7.7 8.6 1.9 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PA26 PF04636.13 CAR26525.1 - 2.7 6.8 7.5 4.9 6.0 7.5 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Rad17 PF03215.15 CAR26526.1 - 9.3e-34 117.0 0.0 2.8e-33 115.4 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 CAR26526.1 - 0.0012 19.2 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MTA_R1 PF17226.2 CAR26526.1 - 0.028 14.6 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 MTA R1 domain Pro-NT_NN PF07421.11 CAR26526.1 - 0.036 14.3 6.9 0.066 13.5 0.1 3.3 3 0 0 3 3 3 0 Neurotensin/neuromedin N precursor UPF0172 PF03665.13 CAR26526.1 - 0.051 13.6 0.6 0.14 12.1 0.6 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) AAA_16 PF13191.6 CAR26526.1 - 0.084 13.2 0.2 0.26 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 CAR26526.1 - 0.11 12.9 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Glutaredoxin PF00462.24 CAR26527.1 - 1.9e-18 66.4 0.2 6.9e-17 61.4 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin Thioredoxin PF00085.20 CAR26527.1 - 6.9e-14 51.7 0.0 1.4e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CAR26527.1 - 5.3e-06 26.7 0.0 0.00053 20.3 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 CAR26527.1 - 0.0027 17.1 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 CAR26527.1 - 0.0028 17.5 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 CAR26527.1 - 0.0058 16.8 0.0 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 CAR26527.1 - 0.0097 15.8 0.0 0.018 14.9 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CAR26527.1 - 0.014 15.8 0.1 0.26 11.8 0.0 2.6 2 2 1 3 3 3 0 Thioredoxin-like domain DIM1 PF02966.16 CAR26527.1 - 0.052 13.3 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Methyltransf_25 PF13649.6 CAR26528.1 - 4.9e-15 56.0 0.0 8.8e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR26528.1 - 3.7e-13 49.9 0.0 6.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR26528.1 - 1.2e-11 44.6 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR26528.1 - 5.7e-11 43.0 0.0 1.2e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR26528.1 - 5.6e-09 36.0 0.0 7.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR26528.1 - 8.8e-06 25.2 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CAR26528.1 - 0.00058 19.9 0.0 0.00088 19.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CAR26528.1 - 0.0017 17.8 0.0 0.0024 17.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CAR26528.1 - 0.039 13.7 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 CAR26528.1 - 0.064 13.4 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 CAR26528.1 - 0.072 12.6 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Rsm22 PF09243.10 CAR26528.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_31 PF13847.6 CAR26529.1 - 4.9e-14 52.4 0.0 7.2e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR26529.1 - 3e-13 50.3 0.0 5.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR26529.1 - 1.2e-11 45.1 0.0 2.1e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR26529.1 - 2.6e-09 37.7 0.0 7.1e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR26529.1 - 2.4e-06 27.5 0.0 3.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR26529.1 - 1.7e-05 24.3 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CAR26529.1 - 0.017 14.7 0.0 0.055 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.13 CAR26529.1 - 0.053 12.9 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.17 CAR26529.1 - 0.054 12.7 0.0 0.11 11.7 0.0 1.5 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 CAR26529.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 CAR26529.1 - 0.21 11.6 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain AAA_12 PF13087.6 CAR26530.1 - 2.7e-56 190.3 0.0 9.8e-56 188.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CAR26530.1 - 1.7e-34 119.8 0.9 9.7e-18 64.9 0.1 3.4 2 2 1 3 3 2 2 AAA domain AAA_19 PF13245.6 CAR26530.1 - 1.9e-11 44.5 0.1 1.5e-10 41.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAR26530.1 - 2.6e-10 40.4 0.0 3.3e-09 36.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CAR26530.1 - 2.6e-06 27.3 0.0 0.034 13.9 0.0 3.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CAR26530.1 - 0.00011 22.2 0.4 0.00045 20.3 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CAR26530.1 - 0.00094 18.8 0.1 0.00094 18.8 0.1 2.7 2 2 0 2 2 1 1 UvrD/REP helicase N-terminal domain DEAD PF00270.29 CAR26530.1 - 0.0012 18.6 0.1 0.0059 16.4 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase PhoH PF02562.16 CAR26530.1 - 0.0057 16.1 0.0 0.04 13.4 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 CAR26530.1 - 0.0073 16.7 0.0 0.041 14.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CAR26530.1 - 0.0082 16.1 0.1 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase UvrD_C_2 PF13538.6 CAR26530.1 - 0.013 15.3 0.0 0.95 9.3 0.0 2.9 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 CAR26530.1 - 0.039 14.2 0.3 0.53 10.6 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CAR26530.1 - 0.046 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CAR26530.1 - 0.054 13.4 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CAR26530.1 - 0.086 12.3 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 CAR26530.1 - 0.16 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) 14-3-3 PF00244.20 CAR26531.1 - 8.1e-105 349.2 5.2 9.4e-105 349.0 5.2 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 CAR26531.1 - 0.006 16.6 0.2 0.015 15.3 0.2 1.7 1 0 0 1 1 1 1 Flagellar protein FlaF Paf1 PF03985.13 CAR26531.1 - 0.01 14.9 0.3 0.01 14.9 0.3 1.4 2 0 0 2 2 2 1 Paf1 FRG PF08867.11 CAR26531.1 - 0.21 12.5 0.9 0.61 11.1 0.1 2.1 2 1 0 2 2 2 0 FRG domain COPI_assoc PF08507.10 CAR26532.1 - 6.2e-42 142.7 8.2 7e-42 142.6 8.2 1.0 1 0 0 1 1 1 1 COPI associated protein Peptidase_M24 PF00557.24 CAR26533.1 - 2.5e-08 33.9 0.0 9.5e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Metallopeptidase family M24 ASH PF15780.5 CAR26533.1 - 0.061 13.5 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CRAL_TRIO PF00650.20 CAR26534.1 - 4.6e-39 133.7 0.0 7.2e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CAR26534.1 - 8.4e-10 38.7 0.2 2.3e-09 37.3 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CAR26534.1 - 2.8e-05 24.3 0.0 4.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain tRNA-synt_1 PF00133.22 CAR26536.1 - 1.9e-55 188.2 0.5 9.7e-35 119.9 1.4 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CAR26536.1 - 6.2e-46 156.3 0.0 1.1e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 CAR26536.1 - 3.7e-27 95.1 0.7 4e-19 68.7 0.0 4.5 4 1 1 5 5 5 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CAR26536.1 - 3e-07 30.5 0.3 6.8e-07 29.4 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CAR26536.1 - 6.3e-06 25.7 0.0 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.19 CAR26536.1 - 0.0029 16.6 0.0 0.0058 15.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (R) zf-ribbon_3 PF13248.6 CAR26536.1 - 0.044 13.2 3.2 2.9 7.4 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain tRNA-synt_1f PF01921.18 CAR26536.1 - 0.051 12.5 0.0 6.6 5.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) DZR PF12773.7 CAR26536.1 - 0.071 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CAR26536.1 - 0.46 10.6 1.7 2.1 8.5 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain SMC_N PF02463.19 CAR26537.1 - 1.2e-26 93.5 5.2 1.1e-25 90.4 5.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CAR26537.1 - 8.9e-18 65.5 3.2 8.9e-18 65.5 3.2 5.2 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.6 CAR26537.1 - 3.3e-11 43.5 13.7 3.3e-11 43.5 13.7 3.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 CAR26537.1 - 1.2e-07 31.9 10.6 0.00088 19.2 0.1 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 CAR26537.1 - 1.9e-05 25.0 0.5 0.001 19.4 0.0 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 CAR26537.1 - 0.00027 20.6 0.0 0.00072 19.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF812 PF05667.11 CAR26537.1 - 0.0035 16.3 11.8 0.0035 16.3 11.8 3.2 2 2 0 2 2 1 1 Protein of unknown function (DUF812) Ploopntkinase3 PF18751.1 CAR26537.1 - 0.025 14.5 0.0 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_13 PF13166.6 CAR26537.1 - 0.034 12.8 58.6 0.012 14.3 10.7 4.4 3 2 1 4 4 4 0 AAA domain HsbA PF12296.8 CAR26537.1 - 0.048 14.1 0.0 0.74 10.3 0.0 3.2 3 0 0 3 3 2 0 Hydrophobic surface binding protein A ABC_tran PF00005.27 CAR26537.1 - 0.091 13.3 0.1 0.091 13.3 0.1 5.2 3 2 0 3 3 2 0 ABC transporter AAA_27 PF13514.6 CAR26537.1 - 0.33 10.5 0.0 0.33 10.5 0.0 4.0 4 0 0 4 4 4 0 AAA domain Spc7 PF08317.11 CAR26537.1 - 1.2 8.0 76.9 0.041 12.8 7.0 6.1 3 2 3 6 6 6 0 Spc7 kinetochore protein Osmo_CC PF08946.10 CAR26537.1 - 3 8.2 11.7 8.7 6.7 3.6 5.2 4 1 0 4 4 3 0 Osmosensory transporter coiled coil ANAPC4 PF12896.7 CAR26537.1 - 4 6.9 16.0 0.54 9.7 0.1 4.1 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF1664 PF07889.12 CAR26537.1 - 4.2 7.4 46.4 0.57 10.2 1.1 7.1 3 2 5 8 8 8 0 Protein of unknown function (DUF1664) Uso1_p115_head PF04869.14 CAR26538.1 - 1.2e-104 349.8 0.2 6.1e-104 347.5 0.2 2.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 CAR26538.1 - 5.9e-18 65.5 32.5 5.9e-18 65.5 32.5 15.6 1 1 11 13 13 13 3 Uso1 / p115 like vesicle tethering protein, C terminal region DUF812 PF05667.11 CAR26538.1 - 5.7e-05 22.2 17.9 5.7e-05 22.2 17.9 9.9 1 1 8 9 9 9 1 Protein of unknown function (DUF812) Spc7 PF08317.11 CAR26538.1 - 0.00012 21.0 324.4 0.0051 15.7 23.8 12.5 1 1 10 13 13 13 9 Spc7 kinetochore protein MscS_porin PF12795.7 CAR26538.1 - 0.00044 19.9 26.5 0.00044 19.9 26.5 10.4 3 1 7 10 10 10 4 Mechanosensitive ion channel porin domain Rab5-bind PF09311.11 CAR26538.1 - 0.00075 19.0 26.6 0.00075 19.0 26.6 10.0 1 1 5 8 8 8 2 Rabaptin-like protein HIP1_clath_bdg PF16515.5 CAR26538.1 - 0.006 17.2 9.0 0.006 17.2 9.0 18.5 1 1 21 22 22 22 4 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 CAR26538.1 - 0.0074 16.3 15.0 0.0074 16.3 15.0 16.6 1 1 16 18 18 18 9 TPR/MLP1/MLP2-like protein Rad52_Rad22 PF04098.15 CAR26539.1 - 3.2e-38 131.0 0.0 3.7e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein TruB-C_2 PF09157.11 CAR26539.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 2 0 0 2 2 2 0 Pseudouridine synthase II TruB, C-terminal IKI3 PF04762.12 CAR26540.1 - 0 1116.5 0.8 0 1116.1 0.8 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 CAR26540.1 - 0.00024 21.3 3.8 0.92 9.9 0.9 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PPR_1 PF12854.7 CAR26540.1 - 0.013 15.1 0.0 0.06 13.1 0.0 2.1 1 0 0 1 1 1 0 PPR repeat TPR_1 PF00515.28 CAR26540.1 - 0.12 12.2 0.2 0.78 9.7 0.2 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SWC7 PF17330.2 CAR26541.1 - 5.8e-41 138.5 0.8 7.2e-41 138.2 0.8 1.1 1 0 0 1 1 1 1 SWR1 chromatin-remodelling complex, sub-unit Swc7 Vac14_Fig4_bd PF11916.8 CAR26542.1 - 7.2e-69 231.0 5.1 7.2e-69 231.0 5.1 1.7 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CAR26542.1 - 4e-47 158.8 2.0 4.4e-38 129.8 0.0 4.4 4 0 0 4 4 4 3 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CAR26542.1 - 6.2e-11 41.6 7.8 0.0014 18.8 0.0 7.2 6 0 0 6 6 6 1 HEAT repeat CLASP_N PF12348.8 CAR26542.1 - 2.7e-07 30.4 1.7 0.0018 17.8 0.5 4.0 3 1 1 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.6 CAR26542.1 - 6.7e-06 26.5 5.1 0.37 11.4 0.1 5.9 6 1 1 7 7 6 2 HEAT-like repeat Cnd1 PF12717.7 CAR26542.1 - 9e-06 25.8 7.6 0.076 13.1 0.9 4.5 2 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CAR26542.1 - 0.00013 22.2 2.6 0.26 11.5 0.2 3.3 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 CAR26542.1 - 0.00015 22.1 4.1 0.23 11.9 0.0 4.9 4 1 1 5 5 4 1 HEAT repeats ParcG PF10274.9 CAR26542.1 - 0.0061 16.7 0.5 3.9 7.6 0.1 2.7 2 0 0 2 2 2 2 Parkin co-regulated protein RIX1 PF08167.12 CAR26542.1 - 0.042 13.6 2.0 0.37 10.5 0.1 3.1 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Tsp45I PF06300.12 CAR26542.1 - 0.059 12.9 0.5 0.13 11.7 0.5 1.5 1 0 0 1 1 1 0 Tsp45I type II restriction enzyme Sigma70_r2 PF04542.14 CAR26542.1 - 0.068 12.9 0.1 4 7.3 0.2 2.5 2 0 0 2 2 2 0 Sigma-70 region 2 Arm PF00514.23 CAR26542.1 - 0.084 13.0 13.7 6 7.1 0.0 5.5 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat DUF3361 PF11841.8 CAR26542.1 - 2.3 8.1 6.5 5 7.0 0.2 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) RasGEF_N_2 PF14663.6 CAR26542.1 - 2.7 8.4 9.7 0.49 10.8 0.2 4.0 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain zf-C2H2_2 PF12756.7 CAR26543.1 - 6.9e-32 109.8 4.7 1.9e-29 101.9 2.1 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) RIBIOP_C PF04950.12 CAR26544.1 - 2.2e-100 335.8 0.0 4.7e-100 334.8 0.0 1.6 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CAR26544.1 - 4.1e-24 84.5 0.0 9.9e-24 83.3 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Ribosomal_S14 PF00253.21 CAR26545.1 - 3e-16 58.9 2.6 3.3e-16 58.8 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 CAR26545.1 - 0.035 14.0 0.3 0.041 13.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Peptidase_M16_M PF16187.5 CAR26546.1 - 1.4e-86 290.3 6.5 1.4e-86 290.3 6.5 2.0 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CAR26546.1 - 1.9e-39 135.0 0.2 5.1e-39 133.6 0.1 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CAR26546.1 - 2.5e-34 118.9 1.7 4.5e-19 69.2 0.0 3.6 3 0 0 3 3 3 2 Peptidase M16 inactive domain UPF0302 PF08864.10 CAR26547.1 - 0.066 13.3 1.0 0.25 11.4 0.1 2.2 2 0 0 2 2 2 0 UPF0302 domain nsp7 PF08716.10 CAR26547.1 - 0.16 12.6 0.2 0.16 12.6 0.2 3.1 4 0 0 4 4 4 0 nsp7 replicase RhoGAP PF00620.27 CAR26547.1 - 0.17 11.7 1.8 0.41 10.5 0.3 2.4 2 0 0 2 2 2 0 RhoGAP domain RIH_assoc PF08454.11 CAR26547.1 - 0.79 9.6 10.1 5.1 7.0 0.6 4.1 4 1 0 4 4 4 0 RyR and IP3R Homology associated UQ_con PF00179.26 CAR26548.1 - 6.7e-44 148.9 0.0 7.7e-44 148.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAR26548.1 - 0.0017 18.1 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CAR26548.1 - 0.46 10.8 2.4 0.45 10.8 1.5 1.7 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.12 CAR26549.1 - 2e-63 214.5 14.7 2e-63 214.5 14.7 1.6 2 0 0 2 2 2 1 Pex19 protein family PilJ PF13675.6 CAR26549.1 - 0.076 13.0 4.9 1.5 8.8 0.1 3.3 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF5454 PF17535.2 CAR26549.1 - 0.15 11.5 0.1 0.15 11.5 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5454) CFEM PF05730.11 CAR26550.1 - 3.8e-08 33.3 10.0 8.4e-08 32.2 10.0 1.6 1 0 0 1 1 1 1 CFEM domain SPX PF03105.19 CAR26550.1 - 0.2 11.5 11.3 0.24 11.3 11.3 1.1 1 0 0 1 1 1 0 SPX domain Menin PF05053.13 CAR26550.1 - 2.4 6.4 12.2 3.3 5.9 12.2 1.2 1 0 0 1 1 1 0 Menin Apt1 PF10351.9 CAR26550.1 - 3.8 6.3 14.0 4.1 6.1 14.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOBP PF15279.6 CAR26550.1 - 5.9 7.4 11.0 7.9 7.0 11.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Arrestin_N PF00339.29 CAR26551.1 - 2.1e-06 27.8 0.2 5.5e-06 26.5 0.2 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain ATP-synt_10 PF05176.14 CAR26552.1 - 3.3e-95 318.2 0.0 4.1e-95 317.9 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein Iso_dh PF00180.20 CAR26553.1 - 5.4e-69 233.0 0.0 6.3e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NTP_transf_6 PF06042.11 CAR26553.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase zf-RING_5 PF14634.6 CAR26554.1 - 3e-07 30.3 10.7 7.2e-07 29.1 10.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CAR26554.1 - 0.027 14.4 9.7 0.097 12.6 9.7 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Pox_A_type_inc PF04508.12 CAR26554.1 - 0.034 14.0 0.0 0.095 12.6 0.0 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Not1 PF04054.15 CAR26554.1 - 0.16 10.8 5.3 0.21 10.4 5.3 1.2 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 BLOC1_2 PF10046.9 CAR26554.1 - 0.33 11.3 4.1 0.72 10.2 0.5 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C3HC4_2 PF13923.6 CAR26554.1 - 0.9 9.4 9.1 3.2 7.7 9.1 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RasGAP_C PF03836.15 CAR26554.1 - 1.2 9.3 9.9 7.1 6.8 9.3 2.3 1 1 0 1 1 1 0 RasGAP C-terminus zf-RING_2 PF13639.6 CAR26554.1 - 1.8 9.0 9.7 4.7 7.6 9.7 1.8 1 0 0 1 1 1 0 Ring finger domain COX7C PF02935.16 CAR26555.1 - 8.2e-23 80.4 3.1 9.3e-23 80.3 3.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Sec1 PF00995.23 CAR26557.1 - 2.8e-82 277.8 4.8 3.5e-82 277.5 4.8 1.0 1 0 0 1 1 1 1 Sec1 family DUF1825 PF08855.10 CAR26557.1 - 0.065 13.2 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) AAA PF00004.29 CAR26558.1 - 4.4e-89 295.7 0.0 9.9e-44 149.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR26558.1 - 1.4e-25 88.8 3.3 1.2e-12 47.5 0.4 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CAR26558.1 - 1.5e-13 50.8 0.0 1.4e-05 24.9 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAR26558.1 - 6e-11 43.0 0.3 2.1e-05 25.0 0.0 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CAR26558.1 - 9.2e-11 41.9 0.1 0.00016 21.7 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAR26558.1 - 2.5e-10 40.7 0.0 0.00039 20.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CAR26558.1 - 2.3e-08 34.4 1.8 0.00022 21.5 0.0 4.1 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 CAR26558.1 - 7.4e-08 32.7 0.0 0.0011 19.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CAR26558.1 - 3.8e-07 30.2 0.0 0.0013 18.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CAR26558.1 - 1.9e-06 27.4 0.9 0.011 15.0 0.0 2.6 3 0 0 3 3 2 2 TIP49 P-loop domain CDC48_N PF02359.18 CAR26558.1 - 8.3e-06 25.9 0.0 2.6e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RNA_helicase PF00910.22 CAR26558.1 - 1.1e-05 25.7 0.0 0.31 11.5 0.0 3.1 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 CAR26558.1 - 2.1e-05 24.0 0.2 0.062 12.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CAR26558.1 - 5.6e-05 23.1 0.0 0.0083 16.1 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 CAR26558.1 - 0.00011 22.1 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 CAR26558.1 - 0.00012 21.9 0.0 0.0027 17.6 0.0 2.8 4 1 0 4 4 3 1 Bacterial dnaA protein AAA_28 PF13521.6 CAR26558.1 - 0.00037 20.8 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CAR26558.1 - 0.00042 19.9 0.1 0.96 8.9 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_11 PF13086.6 CAR26558.1 - 0.00053 19.9 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CAR26558.1 - 0.00055 19.6 3.0 2.3 7.7 0.1 3.7 2 2 1 3 3 3 1 AAA domain AAA_3 PF07726.11 CAR26558.1 - 0.00071 19.4 0.0 0.82 9.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CAR26558.1 - 0.0038 17.2 1.9 3 7.9 0.0 4.6 5 0 0 5 5 4 1 Vps4 C terminal oligomerisation domain NACHT PF05729.12 CAR26558.1 - 0.0041 17.1 0.1 0.13 12.1 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AFG1_ATPase PF03969.16 CAR26558.1 - 0.0069 15.3 0.0 0.23 10.3 0.0 2.4 3 0 0 3 3 3 1 AFG1-like ATPase AAA_18 PF13238.6 CAR26558.1 - 0.007 16.9 0.0 1.1 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CAR26558.1 - 0.0073 16.1 0.0 0.043 13.5 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 CAR26558.1 - 0.0079 16.7 0.0 0.35 11.4 0.0 2.8 2 1 0 2 2 2 1 ABC transporter IstB_IS21 PF01695.17 CAR26558.1 - 0.008 15.9 0.0 4.3 7.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_19 PF13245.6 CAR26558.1 - 0.013 15.8 0.8 0.55 10.6 0.2 3.2 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.6 CAR26558.1 - 0.014 15.1 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CAR26558.1 - 0.016 14.9 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 CAR26558.1 - 0.026 14.7 0.0 1.5 9.0 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CAR26558.1 - 0.043 13.1 0.1 7 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATPase PF06745.13 CAR26558.1 - 0.057 12.8 0.1 17 4.7 0.0 3.1 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.26 CAR26558.1 - 0.093 12.4 0.0 19 4.9 0.0 3.2 3 1 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.13 CAR26558.1 - 0.12 11.5 0.0 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ribonucleas_3_3 PF14622.6 CAR26559.1 - 0.00074 19.7 0.0 0.0027 17.9 0.0 1.9 2 1 0 2 2 2 1 Ribonuclease-III-like DSHCT PF08148.12 CAR26560.1 - 6.9e-46 155.9 0.2 1.5e-45 154.8 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 CAR26560.1 - 2.2e-38 131.1 0.3 6.1e-38 129.7 0.3 1.8 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 CAR26560.1 - 4.7e-20 72.1 0.0 1.2e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 CAR26560.1 - 6.2e-15 55.9 8.0 1.8e-14 54.3 8.0 1.9 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 CAR26560.1 - 2e-07 31.3 0.0 9.7e-07 29.1 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR26560.1 - 6.2e-06 26.3 0.2 1.8e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAR26560.1 - 0.016 15.5 0.3 0.2 11.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Bmp PF02608.14 CAR26560.1 - 0.051 12.5 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter substrate-binding protein PnrA-like DNA_topoisoIV PF00521.20 CAR26560.1 - 1.4 7.7 8.7 0.037 12.9 1.2 2.0 2 1 1 3 3 3 0 DNA gyrase/topoisomerase IV, subunit A FoP_duplication PF13865.6 CAR26560.1 - 3.1 8.4 9.5 7.1 7.3 9.5 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Bromodomain PF00439.25 CAR26561.1 - 1.9e-41 140.0 2.6 9.7e-21 73.6 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 CAR26561.1 - 3.9e-20 71.8 0.9 1.1e-19 70.4 0.9 1.8 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation BRCC36_C PF18110.1 CAR26561.1 - 0.1 12.7 0.1 0.34 11.1 0.1 1.8 1 0 0 1 1 1 0 BRCC36 C-terminal helical domain UPF0524 PF15823.5 CAR26561.1 - 1.5 8.2 3.9 4.2 6.7 3.9 1.8 1 0 0 1 1 1 0 UPF0524 of C3orf70 Bap31 PF05529.12 CAR26562.1 - 4.1e-42 143.2 3.0 5.4e-42 142.9 3.0 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DUF2383 PF09537.10 CAR26562.1 - 0.002 18.5 0.7 0.0032 17.8 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) IFT20 PF14931.6 CAR26562.1 - 0.037 14.2 5.0 0.063 13.5 5.0 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 PKcGMP_CC PF16808.5 CAR26562.1 - 0.038 13.9 4.9 0.038 13.9 4.9 1.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF733 PF05306.11 CAR26562.1 - 0.071 13.4 2.4 0.12 12.7 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF733) S8_pro-domain PF16470.5 CAR26562.1 - 0.1 13.4 0.2 0.17 12.6 0.2 1.4 1 0 0 1 1 1 0 Peptidase S8 pro-domain DivIC PF04977.15 CAR26562.1 - 0.25 11.2 8.1 7 6.5 6.0 2.6 3 0 0 3 3 3 0 Septum formation initiator Bap31_Bap29_C PF18035.1 CAR26562.1 - 0.45 10.5 8.4 0.93 9.5 8.4 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Dus PF01207.17 CAR26563.1 - 1.4e-44 152.5 0.0 1.7e-43 148.9 0.0 2.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.24 CAR26563.1 - 0.0011 18.8 10.4 0.0016 18.3 0.7 2.8 2 1 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAR26563.1 - 0.002 17.9 10.7 0.053 13.3 1.6 3.0 2 1 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CAR26563.1 - 0.073 13.2 0.7 0.073 13.2 0.7 3.0 3 0 0 3 3 3 0 Zinc finger domain Torus PF16131.5 CAR26563.1 - 0.98 10.1 4.2 15 6.3 0.1 2.9 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 CAR26563.1 - 1.2 9.7 5.0 2.2 8.9 0.4 2.7 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-C2H2_aberr PF17017.5 CAR26564.1 - 8e-05 22.8 5.6 0.0048 17.1 0.3 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 CAR26564.1 - 0.00033 20.9 16.4 0.021 15.3 1.1 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CAR26564.1 - 0.0059 16.9 3.8 3.3 8.1 0.1 3.2 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CAR26564.1 - 0.061 14.2 0.6 0.061 14.2 0.6 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR26564.1 - 0.18 12.3 18.7 0.19 12.3 1.2 3.8 3 0 0 3 3 3 0 Zinc-finger double domain Na_trans_assoc PF06512.13 CAR26564.1 - 0.79 10.0 11.6 0.021 15.1 1.9 2.5 2 0 0 2 2 2 0 Sodium ion transport-associated PGA2 PF07543.12 CAR26564.1 - 5.6 6.9 11.4 11 6.0 2.4 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF1765 PF08578.10 CAR26566.1 - 2.3e-19 70.1 8.0 2.3e-19 70.1 8.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1765) BRE1 PF08647.11 CAR26567.1 - 4.3e-27 94.0 11.3 4.3e-27 94.0 11.3 6.3 5 1 1 6 6 5 2 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 CAR26567.1 - 8.2e-08 32.0 11.5 1.8e-07 30.9 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR26567.1 - 9.3e-08 31.8 10.4 2.3e-07 30.6 10.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CAR26567.1 - 2.3e-06 27.3 12.5 7.1e-06 25.8 12.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR26567.1 - 7.8e-06 25.7 13.5 1.9e-05 24.5 13.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CAR26567.1 - 5.2e-05 23.0 14.5 0.00016 21.4 14.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR26567.1 - 0.0007 19.9 12.5 0.0022 18.3 12.5 1.9 1 0 0 1 1 1 1 Ring finger domain DUF2353 PF09789.9 CAR26567.1 - 0.00077 18.9 8.3 0.00077 18.9 8.3 4.4 1 1 4 5 5 5 1 Uncharacterized coiled-coil protein (DUF2353) zf-C2H2 PF00096.26 CAR26567.1 - 0.01 16.3 0.2 0.01 16.3 0.2 3.1 3 0 0 3 3 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CAR26567.1 - 0.014 15.6 1.4 0.94 9.9 0.0 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-RING_UBOX PF13445.6 CAR26567.1 - 0.019 15.0 10.6 0.019 15.0 10.6 2.3 2 0 0 2 2 2 0 RING-type zinc-finger AvrPtoB-E3_ubiq PF09046.10 CAR26567.1 - 0.046 14.0 0.8 0.35 11.1 0.2 2.5 2 0 0 2 2 2 0 AvrPtoB E3 ubiquitin ligase zf-RING_6 PF14835.6 CAR26567.1 - 0.094 12.6 4.8 0.23 11.3 4.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2_4 PF13894.6 CAR26567.1 - 0.23 12.4 0.1 0.23 12.4 0.1 3.3 3 0 0 3 3 2 0 C2H2-type zinc finger zf-RING_4 PF14570.6 CAR26567.1 - 2.9 7.7 10.7 6.6 6.6 10.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ApoO PF09769.9 CAR26567.1 - 3 7.8 9.5 1 9.3 2.6 3.5 3 1 0 3 3 3 0 Apolipoprotein O HypA PF01155.19 CAR26567.1 - 4.4 7.4 14.9 1.7 8.7 0.0 3.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-rbx1 PF12678.7 CAR26567.1 - 4.6 7.6 13.9 0.77 10.1 9.0 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain FYVE PF01363.21 CAR26567.1 - 5.2 7.3 14.8 1e+02 3.1 14.9 2.7 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_4 PF15227.6 CAR26567.1 - 5.8 7.2 10.9 15 5.8 10.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Dus PF01207.17 CAR26568.1 - 8.9e-80 268.1 0.0 1.1e-79 267.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 CAR26568.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain BKACE PF05853.12 CAR26568.1 - 0.15 11.3 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Ribosomal_L31e PF01198.19 CAR26569.1 - 1.2e-36 124.8 1.2 1.4e-36 124.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Rxt3 PF08642.10 CAR26570.1 - 3.6e-24 86.0 2.2 1.1e-12 48.8 0.1 2.7 2 1 1 3 3 3 2 Histone deacetylation protein Rxt3 SUZ PF12752.7 CAR26570.1 - 0.086 13.6 0.7 0.8 10.5 0.3 2.3 2 0 0 2 2 2 0 SUZ domain DUF4050 PF13259.6 CAR26571.1 - 2.8e-07 31.1 9.1 9.1e-06 26.1 0.1 2.9 1 1 2 3 3 3 2 Protein of unknown function (DUF4050) GCN5L1 PF06320.13 CAR26572.1 - 0.00053 20.1 0.2 0.0011 19.1 0.2 1.6 1 1 1 2 2 2 1 GCN5-like protein 1 (GCN5L1) DUF4476 PF14771.6 CAR26572.1 - 0.027 14.8 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Vps39_1 PF10366.9 CAR26573.1 - 6.1e-29 100.5 0.2 6.1e-29 100.5 0.2 3.8 5 0 0 5 5 5 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CAR26573.1 - 2.7e-13 50.3 0.1 9.7e-13 48.5 0.1 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 DUF2175 PF09943.9 CAR26573.1 - 0.005 17.1 0.7 0.016 15.5 0.7 1.9 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) zf-H2C2_2 PF13465.6 CAR26573.1 - 0.16 12.5 0.3 0.47 11.0 0.3 1.8 1 0 0 1 1 1 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 CAR26573.1 - 0.23 11.5 1.5 0.6 10.2 1.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Utp21 PF04192.12 CAR26574.1 - 1.4e-72 244.0 0.6 2e-72 243.5 0.6 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 CAR26574.1 - 3.9e-18 65.5 0.0 3.7e-05 23.9 0.0 5.1 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR26574.1 - 4.8e-12 46.2 12.5 3.6e-08 33.9 0.4 6.9 8 0 0 8 8 8 1 WD domain, G-beta repeat PQQ_2 PF13360.6 CAR26574.1 - 4e-05 23.3 0.0 0.0013 18.4 0.0 2.9 3 0 0 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.16 CAR26574.1 - 0.00024 19.8 0.0 0.0012 17.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain SGL PF08450.12 CAR26574.1 - 0.0013 18.4 0.2 14 5.1 0.0 4.9 5 1 1 6 6 6 1 SMP-30/Gluconolactonase/LRE-like region eIF2A PF08662.11 CAR26574.1 - 0.002 18.1 0.2 0.088 12.7 0.0 3.3 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.15 CAR26574.1 - 0.025 13.9 0.2 1.7 7.9 0.0 3.0 3 1 0 3 3 3 0 CPSF A subunit region PD40 PF07676.12 CAR26574.1 - 0.24 11.4 2.0 0.82 9.7 0.1 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 CAR26574.1 - 0.31 11.6 2.2 5 7.8 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain His_Phos_2 PF00328.22 CAR26575.1 - 2.1e-135 452.0 0.6 3.2e-135 451.4 0.6 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CAR26575.1 - 1.4e-36 124.5 0.0 3.2e-36 123.4 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CAR26575.1 - 8.7e-09 35.2 0.0 2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 CAR26575.1 - 0.039 14.0 1.2 0.11 12.5 0.3 2.3 2 1 0 2 2 2 0 ATP-grasp domain Pribosyltran_N PF13793.6 CAR26576.1 - 6.7e-40 135.7 0.1 2.5e-39 133.8 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CAR26576.1 - 1.1e-37 129.8 1.5 3.5e-30 105.4 0.3 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CAR26576.1 - 8.7e-06 25.3 0.1 0.028 13.9 0.0 2.5 2 1 0 2 2 2 2 Phosphoribosyl transferase domain SRR1 PF07985.12 CAR26577.1 - 3.4e-18 65.4 0.1 7e-18 64.4 0.1 1.6 1 0 0 1 1 1 1 SRR1 EntA_Immun PF08951.10 CAR26577.1 - 0.11 12.9 0.0 0.33 11.3 0.0 1.8 1 0 0 1 1 1 0 Enterocin A Immunity DUF1729 PF08354.10 CAR26578.1 - 5.9e-158 525.4 0.0 9.1e-158 524.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 CAR26578.1 - 4.8e-105 351.6 0.0 5e-104 348.2 0.0 2.5 2 0 0 2 2 2 1 Acyl transferase domain FAS_meander PF17951.1 CAR26578.1 - 8.4e-42 142.4 0.0 2.3e-41 141.0 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 CAR26578.1 - 2.7e-36 123.9 0.0 6.2e-36 122.7 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 CAR26578.1 - 3e-35 121.0 0.2 8.1e-35 119.7 0.2 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta SAT PF16073.5 CAR26578.1 - 1.4e-33 116.6 0.0 6e-33 114.6 0.0 2.0 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 CAR26578.1 - 1e-14 54.8 0.0 3.5e-14 53.1 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 CAR26578.1 - 0.003 17.0 0.0 0.031 13.6 0.0 2.4 1 1 0 1 1 1 1 Nitronate monooxygenase Lipase_3 PF01764.25 CAR26578.1 - 0.37 10.7 1.3 7.1 6.5 0.0 2.9 2 0 0 2 2 2 0 Lipase (class 3) Voldacs PF03517.13 CAR26579.1 - 1.1e-25 90.4 0.2 1.3e-25 90.1 0.2 1.1 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Orn_Arg_deC_N PF02784.16 CAR26580.1 - 9.1e-80 267.6 0.0 1.2e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CAR26580.1 - 3.2e-16 59.3 0.0 4.8e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 CAR26580.1 - 0.0037 16.7 0.0 0.0063 16.0 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel GATA PF00320.27 CAR26581.1 - 3e-09 36.3 8.1 3e-09 36.3 8.1 2.1 2 0 0 2 2 2 1 GATA zinc finger Spt20 PF12090.8 CAR26581.1 - 0.62 9.6 14.0 1.1 8.8 14.0 1.3 1 0 0 1 1 1 0 Spt20 family Mtr2 PF10429.9 CAR26582.1 - 1.3e-68 230.0 0.1 1.6e-68 229.8 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.20 CAR26582.1 - 0.13 12.8 0.0 0.22 12.1 0.0 1.4 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain SUR7 PF06687.12 CAR26583.1 - 1.6e-41 142.2 12.5 1.9e-41 142.0 12.5 1.0 1 0 0 1 1 1 1 SUR7/PalI family ABC_membrane_2 PF06472.15 CAR26585.1 - 2.7e-71 240.1 9.7 3.6e-71 239.7 9.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CAR26585.1 - 7.4e-18 65.4 0.0 2.1e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CAR26585.1 - 2e-05 24.6 0.2 0.00013 21.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CAR26585.1 - 0.00076 20.0 0.2 0.0037 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PBP1_TM PF14812.6 CAR26585.1 - 0.0043 17.4 2.1 0.0095 16.3 2.1 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Rad17 PF03215.15 CAR26585.1 - 0.0045 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 CAR26585.1 - 0.025 14.3 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 CAR26585.1 - 0.05 13.0 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CAR26585.1 - 0.12 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase RRN3 PF05327.11 CAR26585.1 - 1.2 7.6 5.3 8.8 4.7 0.1 2.4 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Vps36_ESCRT-II PF11605.8 CAR26586.1 - 1.6e-29 101.9 0.2 3.9e-29 100.7 0.2 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 CAR26586.1 - 7.9e-21 73.2 3.3 7.9e-21 73.2 3.3 2.7 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain EAP30 PF04157.16 CAR26586.1 - 4.6e-20 71.9 0.0 1.1e-19 70.7 0.0 1.7 1 1 0 1 1 1 1 EAP30/Vps36 family PH_TFIIH PF08567.11 CAR26586.1 - 0.018 15.4 0.0 0.057 13.8 0.0 1.8 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain zf-RanBP PF00641.18 CAR26586.1 - 5.5 6.4 14.0 0.25 10.7 0.9 2.8 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DZR PF12773.7 CAR26586.1 - 7.1 6.7 10.9 0.54 10.3 1.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon Mo25 PF08569.11 CAR26587.1 - 1.9e-111 372.5 15.0 2.2e-111 372.4 15.0 1.0 1 0 0 1 1 1 1 Mo25-like ILEI PF15711.5 CAR26587.1 - 0.0069 16.8 3.7 0.054 14.0 0.3 2.7 1 1 1 2 2 2 1 Interleukin-like EMT inducer DUF3361 PF11841.8 CAR26587.1 - 0.05 13.5 4.1 0.12 12.3 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) U62_UL91 PF17442.2 CAR26587.1 - 0.08 12.9 0.8 1.1 9.3 0.0 2.9 3 0 0 3 3 3 0 Functional domain of U62 and UL91 proteins CDC73_C PF05179.14 CAR26588.1 - 1.8e-56 190.2 0.9 2.8e-56 189.5 0.9 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal OB_NTP_bind PF07717.16 CAR26589.1 - 4.6e-16 59.0 0.0 1.4e-15 57.4 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAR26589.1 - 3.9e-14 53.0 0.1 9.4e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 CAR26589.1 - 3.5e-10 40.2 0.1 1.5e-09 38.1 0.1 2.2 1 1 0 1 1 1 1 RWD domain DEAD PF00270.29 CAR26589.1 - 1.1e-08 35.0 0.5 1.1e-08 35.0 0.5 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase HA2 PF04408.23 CAR26589.1 - 1.2e-06 28.7 4.9 1.3e-06 28.7 0.0 3.0 3 0 0 3 3 2 1 Helicase associated domain (HA2) PhoH PF02562.16 CAR26589.1 - 0.00031 20.3 0.0 0.0058 16.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 CAR26589.1 - 0.00059 20.1 0.1 0.0022 18.3 0.1 2.0 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CAR26589.1 - 0.0013 17.9 0.1 0.0025 16.9 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 CAR26589.1 - 0.0026 17.5 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.6 CAR26589.1 - 0.0032 17.8 0.2 0.0077 16.6 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CAR26589.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CAR26589.1 - 0.0061 15.9 0.6 0.054 12.8 0.0 2.5 3 0 0 3 3 3 1 KaiC FtsK_SpoIIIE PF01580.18 CAR26589.1 - 0.0063 15.9 0.1 0.02 14.2 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF1296 PF06972.11 CAR26589.1 - 0.0076 16.4 1.6 0.067 13.3 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1296) AAA_7 PF12775.7 CAR26589.1 - 0.017 14.7 0.1 0.053 13.0 0.1 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 CAR26589.1 - 0.024 14.4 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CAR26589.1 - 0.026 15.0 0.0 0.026 15.0 0.0 3.9 3 1 0 3 3 2 0 AAA domain Zot PF05707.12 CAR26589.1 - 0.035 13.8 0.1 0.18 11.4 0.1 2.1 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) CDRT4 PF15213.6 CAR26589.1 - 1.2 9.7 9.8 0.89 10.2 1.7 2.9 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein Pox_RNA_Pol_19 PF05320.12 CAR26589.1 - 5.5 6.9 9.1 1.1 9.3 0.1 3.2 4 0 0 4 4 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Glyco_hydro_32N PF00251.20 CAR26590.1 - 7.6e-83 278.6 4.8 7.6e-83 278.6 4.8 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CAR26590.1 - 1.5e-10 41.3 0.0 2.8e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF2724 PF10893.8 CAR26590.1 - 0.035 14.0 0.1 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2724) MFS_1 PF07690.16 CAR26591.1 - 1.4e-27 96.6 20.1 1.4e-27 96.6 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.8 CAR26591.1 - 5e-06 25.4 10.3 5e-06 25.4 10.3 1.6 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like EF-hand_1 PF00036.32 CAR26592.1 - 1.8e-24 83.4 12.6 1e-05 24.7 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CAR26592.1 - 1.2e-21 76.9 8.5 1.3e-12 48.0 1.9 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAR26592.1 - 1.5e-19 68.2 7.4 9.5e-05 22.0 0.4 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CAR26592.1 - 1.9e-15 55.6 12.6 0.00065 19.1 0.4 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CAR26592.1 - 1.1e-10 41.1 16.4 0.015 15.1 0.3 4.5 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CAR26592.1 - 1.5e-06 28.1 9.7 0.02 14.8 0.4 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CAR26592.1 - 2e-05 24.9 0.1 0.24 11.7 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CAR26592.1 - 0.0017 18.6 0.1 4.3 7.8 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain Nse4-Nse3_bdg PF15412.6 CAR26592.1 - 0.13 12.4 4.4 3 8.0 0.1 2.9 3 0 0 3 3 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE Diphthamide_syn PF01866.17 CAR26593.1 - 1.7e-71 241.1 0.0 2.2e-71 240.8 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein UL73_N PF12522.8 CAR26593.1 - 0.47 10.2 4.1 1.3 8.8 4.1 1.7 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Amidohydro_2 PF04909.14 CAR26594.1 - 7.2e-08 32.5 0.0 1.8e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 CAR26594.1 - 0.00011 21.6 0.0 0.00019 20.9 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family RepB_primase PF16793.5 CAR26594.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 RepB DNA-primase from phage plasmid Proteasom_Rpn13 PF04683.13 CAR26595.1 - 2e-22 79.5 0.0 2.8e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor CinA PF02464.17 CAR26596.1 - 1.3e-32 112.5 0.0 1.6e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein DHR-2 PF06920.13 CAR26597.1 - 4.5e-39 134.5 3.1 1.6e-38 132.6 3.1 1.9 1 1 0 1 1 1 1 Dock homology region 2 GBR_NSP5 PF17580.2 CAR26597.1 - 0.13 12.0 1.8 0.3 10.9 0.6 2.1 2 0 0 2 2 2 0 Group B Rotavirus Non-structural protein 5 PP-binding PF00550.25 CAR26598.1 - 1.4e-09 38.1 0.3 1.8e-09 37.8 0.3 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CAR26598.1 - 2.1e-05 24.6 0.6 3.2e-05 24.0 0.6 1.3 1 0 0 1 1 1 1 Acyl-carrier LRR_4 PF12799.7 CAR26599.1 - 7.9e-30 102.4 38.8 8.5e-11 41.9 2.0 7.5 4 2 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAR26599.1 - 2.6e-26 91.1 31.3 5.6e-08 32.4 0.2 6.4 3 2 1 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 CAR26599.1 - 5.2e-16 58.6 20.9 4.6e-07 29.5 2.9 5.0 1 1 5 6 6 6 4 Leucine-rich repeat LRR_1 PF00560.33 CAR26599.1 - 0.00034 20.7 28.6 0.65 10.8 0.2 8.6 8 2 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 CAR26599.1 - 0.029 14.4 20.6 3.3 8.0 0.1 6.6 7 0 0 7 7 7 0 Leucine Rich repeat MRP-63 PF14978.6 CAR26599.1 - 0.092 13.4 0.3 2.1 9.0 0.3 2.4 1 1 0 1 1 1 0 Mitochondrial ribosome protein 63 LRR_5 PF13306.6 CAR26599.1 - 0.16 11.9 10.5 0.1 12.6 0.5 2.9 1 1 3 4 4 4 0 BspA type Leucine rich repeat region (6 copies) UB2H PF14814.6 CAR26599.1 - 0.29 11.2 2.4 37 4.4 0.1 4.3 2 2 4 6 6 6 0 Bifunctional transglycosylase second domain tRNA-synt_2b PF00587.25 CAR26600.1 - 2.2e-46 158.1 0.0 4.1e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CAR26600.1 - 6e-17 61.6 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain APG17 PF04108.12 CAR26601.1 - 1.6e-91 307.4 15.4 1.8e-91 307.2 15.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Bap31_Bap29_C PF18035.1 CAR26601.1 - 0.0013 18.7 0.5 2.7 8.1 0.1 3.2 2 0 0 2 2 2 2 Bap31/Bap29 cytoplasmic coiled-coil domain Lip_prot_lig_C PF10437.9 CAR26601.1 - 0.028 14.4 3.3 0.34 10.9 0.1 3.5 3 1 1 4 4 4 0 Bacterial lipoate protein ligase C-terminus DUF2026 PF09641.10 CAR26601.1 - 0.036 13.7 0.4 0.23 11.1 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2026) Glyco_transf_88 PF16849.5 CAR26601.1 - 0.07 12.0 5.9 0.067 12.1 4.8 1.5 1 1 0 1 1 1 0 Glycosyltransferase family 88 Cluap1 PF10234.9 CAR26601.1 - 0.093 12.1 12.9 0.025 14.0 5.2 2.7 1 1 2 3 3 3 0 Clusterin-associated protein-1 DASH_Dad2 PF08654.10 CAR26601.1 - 0.34 11.3 3.3 2.1 8.8 0.0 3.4 3 1 0 3 3 3 0 DASH complex subunit Dad2 SPATA1_C PF15743.5 CAR26601.1 - 6.7 6.8 12.1 0.71 9.9 3.4 2.7 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus DUF745 PF05335.13 CAR26601.1 - 8.2 6.1 8.0 34 4.1 2.7 3.2 3 1 2 5 5 5 0 Protein of unknown function (DUF745) G-patch PF01585.23 CAR26602.1 - 3.6e-13 49.2 2.0 7.7e-13 48.1 2.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CAR26602.1 - 2.4e-06 27.5 0.4 4.6e-06 26.6 0.4 1.4 1 0 0 1 1 1 1 G-patch domain CHCH PF06747.13 CAR26603.1 - 3.5e-08 33.4 4.8 6.8e-08 32.5 4.8 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 CAR26603.1 - 0.00014 22.2 4.3 0.00014 22.2 4.3 1.7 2 0 0 2 2 2 1 GCK domain Synaptobrevin PF00957.21 CAR26604.1 - 1.7e-15 56.5 1.0 3.1e-15 55.7 1.0 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CAR26604.1 - 4.7e-11 42.6 0.0 8.1e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Herpes_teg_N PF04843.12 CAR26604.1 - 0.065 12.9 0.1 0.22 11.2 0.1 1.8 2 1 0 2 2 2 0 Herpesvirus tegument protein, N-terminal conserved region DUF5452 PF17533.2 CAR26604.1 - 0.11 12.5 1.5 0.16 12.0 1.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5452) FMN_dh PF01070.18 CAR26605.1 - 3.3e-119 398.0 0.0 4.2e-119 397.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CAR26605.1 - 2.5e-20 72.4 0.0 4.9e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CAR26605.1 - 9.8e-06 24.9 0.1 3.9e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CAR26605.1 - 2.3e-05 23.6 1.2 0.0013 17.8 0.0 2.6 1 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CAR26605.1 - 0.00018 21.0 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 CAR26605.1 - 0.041 13.3 0.7 3 7.3 0.0 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 CAR26605.1 - 0.055 12.8 0.0 11 5.3 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG CNH PF00780.22 CAR26606.1 - 3.7e-19 69.4 0.9 1e-18 67.9 0.9 1.7 1 1 0 1 1 1 1 CNH domain RhoGEF PF00621.20 CAR26606.1 - 2.4e-08 34.5 0.0 2.4e-08 34.5 0.0 2.2 3 0 0 3 3 3 1 RhoGEF domain PH_5 PF15405.6 CAR26606.1 - 0.00025 21.2 2.3 0.00034 20.7 0.2 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CAR26606.1 - 0.0065 17.0 5.0 0.16 12.5 0.2 3.4 4 0 0 4 4 4 2 PH domain adh_short PF00106.25 CAR26607.1 - 6e-26 91.1 0.0 8.4e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR26607.1 - 2.9e-14 53.2 0.0 3.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR26607.1 - 7.5e-07 29.2 1.3 9.1e-06 25.7 1.3 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 CAR26607.1 - 0.0012 17.9 0.1 0.0026 16.8 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family PfaD_N PF18328.1 CAR26607.1 - 0.0022 17.9 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit PfaD N-terminal domain Epimerase PF01370.21 CAR26607.1 - 0.021 14.3 0.1 0.055 12.9 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family LRR_RI_capping PF18779.1 CAR26607.1 - 0.029 14.0 1.6 2.6 7.8 0.2 3.3 3 0 0 3 3 3 0 Capping Ribonuclease inhibitor Leucine Rich Repeat SPC25 PF06703.11 CAR26608.1 - 5.9e-37 127.0 1.9 6.8e-37 126.8 1.9 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) zf-RING_UBOX PF13445.6 CAR26609.1 - 4e-07 29.9 5.0 8.9e-07 28.8 5.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CAR26609.1 - 3.1e-06 27.4 4.5 5.8e-06 26.5 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CAR26609.1 - 3.8e-06 26.7 1.5 8.8e-06 25.5 1.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR26609.1 - 0.00036 20.4 5.1 0.00096 19.1 5.1 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CAR26609.1 - 0.00048 20.2 6.3 0.0014 18.7 6.3 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CAR26609.1 - 0.0016 18.3 6.6 0.0095 15.8 6.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR26609.1 - 0.0079 16.0 1.9 0.0079 16.0 1.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR26609.1 - 0.02 14.7 10.6 1.7 8.5 6.8 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CAR26609.1 - 0.057 13.2 2.7 0.13 12.1 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.21 CAR26609.1 - 0.4 10.9 1.7 33 4.8 0.0 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE PF01363.21 CAR26609.1 - 0.8 9.9 3.6 3.2 7.9 3.6 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-rbx1 PF12678.7 CAR26609.1 - 1.4 9.2 4.9 5.9 7.3 4.9 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain Lar_restr_allev PF14354.6 CAR26609.1 - 3 8.3 4.0 54 4.3 0.9 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar DUF1899 PF08953.11 CAR26610.1 - 1.2e-30 105.2 0.2 2.5e-30 104.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CAR26610.1 - 4.5e-20 71.3 0.2 9.2e-20 70.3 0.2 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CAR26610.1 - 5.6e-15 55.5 1.2 0.00011 22.9 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 CAR26610.1 - 2.8e-07 29.6 0.3 9.6e-05 21.2 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CAR26610.1 - 4.3e-05 23.7 0.1 0.0024 18.1 0.1 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CAR26610.1 - 0.0071 14.9 0.0 0.012 14.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.11 CAR26610.1 - 0.022 14.7 0.1 0.48 10.3 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR26610.1 - 0.084 11.8 0.0 0.36 9.7 0.0 1.9 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SEN1_N PF12726.7 CAR26611.1 - 1.1e-211 705.0 14.4 1.6e-211 704.5 14.4 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 CAR26611.1 - 6.2e-70 236.0 0.2 6.2e-70 236.0 0.2 2.6 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.6 CAR26611.1 - 1.5e-61 207.5 0.2 3.1e-61 206.5 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR26611.1 - 1.1e-08 35.5 0.0 7.6e-08 32.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR26611.1 - 2e-08 34.2 0.0 0.00035 20.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CAR26611.1 - 6.1e-06 26.1 0.1 0.07 12.9 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CAR26611.1 - 0.00058 19.5 7.8 0.0013 18.4 0.0 3.5 3 2 0 3 3 3 1 UvrD/REP helicase N-terminal domain Phage_ABA_S PF18066.1 CAR26611.1 - 0.014 16.1 0.0 29 5.5 0.0 3.7 3 0 0 3 3 3 0 Phage ABA sandwich domain ZapB PF06005.12 CAR26611.1 - 0.093 13.2 3.8 2.6 8.6 1.7 3.0 2 0 0 2 2 2 0 Cell division protein ZapB DUF2730 PF10805.8 CAR26612.1 - 0.12 12.4 1.5 1.2 9.3 0.0 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF2730) UL11 PF11094.8 CAR26612.1 - 0.16 11.9 0.6 2.1 8.3 0.1 2.4 2 0 0 2 2 2 0 Membrane-associated tegument protein IMPDH PF00478.25 CAR26613.1 - 4.6e-131 436.9 3.3 5.2e-131 436.7 3.3 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CAR26613.1 - 5.1e-13 49.2 0.0 2.6e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain His_biosynth PF00977.21 CAR26613.1 - 6.3e-06 25.8 1.7 0.0029 17.1 0.2 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein FMN_dh PF01070.18 CAR26613.1 - 6.7e-06 25.4 2.2 6.3e-05 22.2 3.3 2.0 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CAR26613.1 - 4.4e-05 23.0 5.0 0.012 15.1 1.3 2.8 3 1 1 4 4 4 2 Nitronate monooxygenase ThiG PF05690.14 CAR26613.1 - 0.053 12.8 0.1 0.25 10.6 0.4 1.9 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Metallophos PF00149.28 CAR26614.1 - 5.3e-35 121.8 0.0 1e-34 120.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WGG PF10273.9 CAR26615.1 - 2.8e-27 95.2 1.1 2.8e-27 95.2 1.1 1.6 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 Hid1 PF12722.7 CAR26616.1 - 3.6e-61 207.4 24.0 2.7e-35 121.8 1.3 4.2 2 2 0 2 2 2 2 High-temperature-induced dauer-formation protein RNR_inhib PF08591.10 CAR26617.1 - 1.1e-05 26.7 0.3 2.1e-05 25.8 0.3 1.6 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Aminotran_3 PF00202.21 CAR26618.1 - 1.5e-123 412.5 0.0 1.7e-123 412.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CAR26618.1 - 0.00013 21.4 0.0 0.00037 19.9 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CAR26618.1 - 0.013 14.7 0.0 0.09 11.9 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II Pea-VEAacid PF08111.11 CAR26618.1 - 0.16 12.4 1.6 0.39 11.1 1.6 1.7 1 0 0 1 1 1 0 Pea-VEAacid family cNMP_binding PF00027.29 CAR26619.1 - 6.7e-30 103.0 0.3 1.9e-13 50.3 0.0 6.1 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 CAR26619.1 - 7.7e-20 71.9 0.5 1.6e-12 48.0 0.8 3.4 3 0 0 3 3 3 2 Patatin-like phospholipase TRAP-gamma PF07074.12 CAR26619.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) LSM PF01423.22 CAR26620.1 - 1.2e-18 66.5 0.1 1.4e-18 66.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CAR26620.1 - 0.015 15.4 0.0 0.032 14.4 0.0 1.6 1 1 1 2 2 2 0 RimP C-terminal SH3 domain SH3_9 PF14604.6 CAR26620.1 - 0.18 11.7 0.1 19 5.2 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain MRP-L47 PF06984.13 CAR26621.1 - 1.7e-26 92.2 1.4 5.3e-26 90.6 0.7 2.1 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2884 PF11101.8 CAR26621.1 - 0.043 13.3 0.5 0.075 12.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) OGG_N PF07934.12 CAR26622.1 - 4.7e-21 75.1 0.6 7.8e-21 74.4 0.1 1.6 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CAR26622.1 - 1.7e-19 70.3 0.0 2.7e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PIF1 PF05970.14 CAR26623.1 - 7.7e-73 245.7 1.0 1.1e-69 235.4 1.0 2.4 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CAR26623.1 - 1.3e-18 67.5 0.0 2.1e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR26623.1 - 6.6e-09 36.3 0.0 1.6e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CAR26623.1 - 0.0015 18.0 0.1 0.0037 16.7 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CAR26623.1 - 0.003 17.9 0.1 0.013 15.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 CAR26623.1 - 0.0042 15.1 0.3 0.045 11.7 0.0 2.1 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 CAR26623.1 - 0.0045 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 CAR26623.1 - 0.0052 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region DEAD PF00270.29 CAR26623.1 - 0.0096 15.7 0.1 3 7.6 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_5 PF07728.14 CAR26623.1 - 0.06 13.3 0.3 0.5 10.4 0.3 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 CAR26623.1 - 0.065 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 CAR26623.1 - 1.1 9.7 4.6 3.4 8.2 0.2 3.2 2 1 1 3 3 3 0 ABC transporter Sec39 PF08314.11 CAR26624.1 - 1.7e-107 360.8 10.8 2.6e-105 353.6 10.8 2.0 1 1 0 1 1 1 1 Secretory pathway protein Sec39 THOC7 PF05615.13 CAR26625.1 - 7.7e-09 35.9 6.3 7.7e-09 35.9 6.3 2.6 3 1 0 3 3 2 1 Tho complex subunit 7 HAUS6_N PF14661.6 CAR26625.1 - 0.0057 16.3 1.9 0.0057 16.3 1.9 2.5 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus Laminin_II PF06009.12 CAR26625.1 - 0.02 14.9 2.1 0.02 14.9 2.1 2.2 2 1 1 3 3 3 0 Laminin Domain II EMP24_GP25L PF01105.24 CAR26625.1 - 0.064 13.2 2.3 0.17 11.8 2.3 1.7 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SCVP PF17619.2 CAR26625.1 - 0.099 13.5 0.9 12 6.9 0.0 2.8 2 0 0 2 2 2 0 Secreted clade V proteins TRPM_tetra PF16519.5 CAR26625.1 - 0.2 11.8 4.4 0.16 12.1 2.1 2.0 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DUF1664 PF07889.12 CAR26625.1 - 0.36 10.9 4.0 0.39 10.8 0.7 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Prominin PF05478.11 CAR26625.1 - 0.44 8.4 3.2 0.52 8.2 3.2 1.3 1 0 0 1 1 1 0 Prominin ZYG-11_interact PF05884.12 CAR26625.1 - 0.48 9.8 1.6 0.84 9.0 1.6 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 Fib_alpha PF08702.10 CAR26625.1 - 2.5 8.3 12.7 3.2 7.9 1.0 3.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 CAR26625.1 - 2.8 8.4 10.9 1.1 9.7 2.4 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Ribosomal_S3Ae PF01015.18 CAR26626.1 - 6e-84 280.6 5.8 7.1e-84 280.4 5.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 CAR26626.1 - 0.044 14.3 0.2 0.1 13.2 0.2 1.7 1 1 0 1 1 1 0 Translation initiation factor SUI1 Ras PF00071.22 CAR26627.1 - 2e-29 102.3 0.0 2.5e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR26627.1 - 1.9e-20 73.3 0.0 3.3e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR26627.1 - 8.9e-05 22.0 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR26627.1 - 0.00017 21.0 0.1 0.00022 20.7 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 CAR26627.1 - 0.0024 17.4 0.6 0.0071 15.9 0.1 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region DLIC PF05783.11 CAR26627.1 - 0.0053 15.7 0.0 0.54 9.0 0.0 2.0 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 CAR26627.1 - 0.043 13.9 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_lid_10 PF17872.1 CAR26628.1 - 6.5e-42 141.7 0.0 3.6e-41 139.3 0.0 2.3 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 CAR26628.1 - 3.8e-20 72.7 0.0 9.1e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 CAR26628.1 - 4.6e-17 62.0 1.3 6.9e-17 61.4 0.1 2.0 2 0 0 2 2 2 1 BAH domain AAA_16 PF13191.6 CAR26628.1 - 1.8e-07 31.7 9.2 2.3e-06 28.1 0.0 4.0 5 0 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 CAR26628.1 - 8.4e-07 29.3 0.0 3.2e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CAR26628.1 - 0.00051 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Merozoite_SPAM PF07133.11 CAR26628.1 - 0.0011 19.0 32.8 0.0011 19.0 32.8 2.6 2 0 0 2 2 2 1 Merozoite surface protein (SPAM) AAA_19 PF13245.6 CAR26628.1 - 0.0049 17.2 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF1075 PF06388.11 CAR26628.1 - 0.011 15.8 0.5 0.038 14.0 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) MeaB PF03308.16 CAR26628.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SUR7 PF06687.12 CAR26629.1 - 4.1e-11 42.9 4.8 6.7e-11 42.2 4.8 1.4 1 0 0 1 1 1 1 SUR7/PalI family AI-2E_transport PF01594.16 CAR26629.1 - 0.0059 15.8 1.1 0.011 14.9 0.0 1.9 3 0 0 3 3 3 1 AI-2E family transporter Claudin_2 PF13903.6 CAR26630.1 - 0.8 9.4 6.5 0.66 9.7 1.1 2.2 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4389 PF14333.6 CAR26630.1 - 4 7.4 8.0 0.33 10.9 1.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4389) SUR7 PF06687.12 CAR26630.1 - 6.2 6.4 15.1 1.1e+02 2.3 15.1 2.4 1 1 0 1 1 1 0 SUR7/PalI family COPIIcoated_ERV PF07970.12 CAR26631.1 - 2.6e-29 102.7 0.0 3.9e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CAR26631.1 - 4.6e-23 81.4 0.1 8.7e-23 80.5 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IBR PF01485.21 CAR26633.1 - 1.5e-14 53.9 45.1 1.1e-07 31.9 4.3 4.0 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CAR26633.1 - 0.0024 17.7 9.0 0.0024 17.7 9.0 4.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR26633.1 - 0.0028 18.0 7.1 0.0028 18.0 7.1 5.0 3 2 2 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 CAR26633.1 - 0.0042 17.1 6.0 0.0042 17.1 6.0 3.7 3 1 0 3 3 3 2 RING-type zinc-finger CopK PF11525.8 CAR26633.1 - 0.089 12.4 0.6 0.37 10.4 0.1 2.1 2 0 0 2 2 2 0 Copper resistance protein K Gal4_dimer PF03902.13 CAR26633.1 - 0.46 10.7 1.9 0.73 10.0 0.7 2.0 2 0 0 2 2 2 0 Gal4-like dimerisation domain SSrecog PF03531.14 CAR26634.1 - 7.9e-28 96.2 1.3 1.3e-26 92.3 0.0 3.2 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 CAR26634.1 - 2.3e-27 95.2 0.1 2.6e-25 88.6 0.0 2.7 2 0 0 2 2 2 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 CAR26634.1 - 1.8e-26 92.3 0.0 1.5e-24 86.2 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Dak1 PF02733.17 CAR26635.1 - 1e-102 343.2 1.7 1.3e-102 342.9 1.7 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CAR26635.1 - 2.2e-45 154.7 2.3 6e-45 153.3 2.5 1.7 2 0 0 2 2 2 1 DAK2 domain HTH_7 PF02796.15 CAR26635.1 - 0.19 11.8 0.1 0.62 10.2 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase BAR PF03114.18 CAR26636.1 - 3.8e-05 23.5 0.0 0.00011 21.9 0.0 1.6 1 1 0 1 1 1 1 BAR domain Zn_clus PF00172.18 CAR26637.1 - 1.8e-05 24.7 8.1 3.4e-05 23.9 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5601 PF18151.1 CAR26637.1 - 0.041 14.2 0.5 1.4 9.3 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) Imm3 PF14425.6 CAR26637.1 - 0.39 10.8 0.0 0.39 10.8 0.0 2.7 3 0 0 3 3 3 0 Immunity protein Imm3 Hexokinase_1 PF00349.21 CAR26638.1 - 6.1e-18 65.4 0.0 9.3e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 CAR26638.1 - 2.5e-13 50.0 0.0 1.1e-12 47.9 0.0 1.9 1 1 0 1 1 1 1 Hexokinase Cyt-b5 PF00173.28 CAR26639.1 - 2.1e-09 37.4 0.1 3.5e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain vATP-synt_AC39 PF01992.16 CAR26640.1 - 1.7e-102 343.4 3.8 1.9e-102 343.3 3.8 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit SF3A3 PF16837.5 CAR26640.1 - 0.13 12.8 1.3 25 5.4 0.0 3.1 2 1 1 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 Dor1 PF04124.12 CAR26641.1 - 1.1e-38 132.8 2.6 3.7e-37 127.8 2.6 2.2 1 1 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 CAR26641.1 - 0.0012 18.7 0.5 0.0055 16.5 0.5 2.2 1 1 0 1 1 1 1 Exocyst complex component Sec5 DUF2630 PF10944.8 CAR26641.1 - 0.032 14.7 2.7 0.058 13.9 1.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2630) FliT PF05400.13 CAR26641.1 - 0.08 13.8 3.4 0.12 13.2 0.1 3.0 2 1 0 2 2 2 0 Flagellar protein FliT DUF4533 PF15047.6 CAR26641.1 - 0.32 10.5 5.6 7.6 6.0 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF4533) C2 PF00168.30 CAR26642.1 - 2.3e-56 188.4 0.3 2e-15 56.9 0.0 5.9 6 0 0 6 6 6 5 C2 domain Ribosomal_L6e PF01159.19 CAR26643.1 - 2e-37 128.1 1.0 2.7e-37 127.7 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e FKBP_C PF00254.28 CAR26644.1 - 8.8e-28 96.5 0.5 8.1e-27 93.4 0.1 2.5 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CAR26644.1 - 2.4e-18 66.6 10.4 2.4e-18 66.6 10.4 3.7 2 2 0 2 2 2 1 Nucleoplasmin-like domain GAGA_bind PF06217.12 CAR26644.1 - 1.3 9.2 25.4 1 9.6 2.9 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family HMG-CoA_red PF00368.18 CAR26645.1 - 1.4e-140 468.5 1.0 1.9e-140 468.0 1.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 CAR26645.1 - 7.6e-41 139.6 0.6 1.3e-40 138.8 0.6 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 CAR26645.1 - 3.8e-11 43.1 7.0 9.5e-11 41.8 7.0 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation DUF3810 PF12725.7 CAR26645.1 - 1.2 8.4 6.7 16 4.7 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3810) Zn_clus PF00172.18 CAR26646.1 - 6.7e-05 22.9 8.4 0.00012 22.1 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sybindin PF04099.12 CAR26647.1 - 3.4e-17 62.7 0.3 4.3e-17 62.4 0.3 1.1 1 0 0 1 1 1 1 Sybindin-like family LptD PF04453.14 CAR26647.1 - 0.026 13.8 0.2 0.03 13.5 0.2 1.1 1 0 0 1 1 1 0 LPS transport system D Sedlin_N PF04628.13 CAR26647.1 - 0.032 14.4 0.1 0.041 14.0 0.1 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region ABC2_membrane PF01061.24 CAR26648.1 - 8.4e-62 208.3 62.4 5e-39 133.9 15.1 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CAR26648.1 - 2.5e-36 125.2 0.0 1.4e-18 67.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CAR26648.1 - 5e-36 122.5 4.6 1.5e-30 105.0 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CAR26648.1 - 2.1e-10 40.2 34.3 2e-08 33.8 12.5 3.5 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 CAR26648.1 - 4.2e-07 30.5 0.2 1.1e-06 29.1 0.2 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CAR26648.1 - 2.2e-05 24.9 0.2 0.0031 17.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAR26648.1 - 3.1e-05 23.9 0.1 0.00022 21.1 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 CAR26648.1 - 0.00015 21.6 0.0 0.55 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CAR26648.1 - 0.00044 20.8 0.5 0.01 16.3 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.6 CAR26648.1 - 0.0018 18.6 0.8 0.0084 16.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CAR26648.1 - 0.0023 17.6 0.7 0.078 12.7 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 CAR26648.1 - 0.0074 15.7 0.0 0.62 9.5 0.0 3.2 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 CAR26648.1 - 0.0076 15.9 0.1 0.021 14.4 0.1 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CAR26648.1 - 0.011 15.5 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CAR26648.1 - 0.014 15.5 0.5 0.13 12.3 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase RgpF PF05045.12 CAR26648.1 - 0.019 13.8 0.7 0.037 12.8 0.5 1.5 2 0 0 2 2 2 0 Rhamnan synthesis protein F AAA_25 PF13481.6 CAR26648.1 - 0.02 14.4 0.2 0.15 11.7 0.1 2.3 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CAR26648.1 - 0.043 14.2 0.0 0.72 10.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 CAR26648.1 - 0.077 12.9 1.1 0.31 10.9 0.2 2.4 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 CAR26648.1 - 0.097 12.7 0.2 0.32 11.0 0.2 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CAR26648.1 - 0.62 9.8 2.5 4.1 7.1 0.9 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CAR26648.1 - 0.65 10.5 0.0 0.65 10.5 0.0 2.5 4 0 0 4 4 2 0 AAA domain ENTH PF01417.20 CAR26649.1 - 5.7e-43 145.9 0.1 9e-43 145.3 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CAR26649.1 - 0.0089 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 CAR26649.1 - 0.02 14.7 1.3 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 VHS domain DUF2457 PF10446.9 CAR26649.1 - 6.4 5.8 17.7 0.77 8.8 9.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Pro_isomerase PF00160.21 CAR26650.1 - 5.7e-47 159.9 0.0 7.1e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TFR_dimer PF04253.15 CAR26651.1 - 2.7e-13 50.1 0.0 6.4e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CAR26651.1 - 4.9e-08 32.9 0.0 8.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CAR26651.1 - 0.00021 21.2 0.0 0.00048 20.1 0.0 1.5 1 0 0 1 1 1 1 PA domain Cupin_5 PF06172.11 CAR26652.1 - 2.4e-42 144.4 0.0 3e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Dus PF01207.17 CAR26653.1 - 2e-79 266.9 0.0 2.5e-79 266.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-C2H2 PF00096.26 CAR26654.1 - 2.8e-06 27.4 14.5 0.00023 21.4 2.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR26654.1 - 3.6e-06 27.1 9.0 3.3e-05 24.1 4.9 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR26654.1 - 0.001 19.7 14.0 0.009 16.8 2.3 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger NDUF_B6 PF09782.9 CAR26654.1 - 1.4 9.0 4.3 1.3 9.1 0.1 2.9 4 0 0 4 4 4 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit Fer4 PF00037.27 CAR26654.1 - 3.6 7.6 4.3 8.6 6.4 0.4 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Methyltransf_16 PF10294.9 CAR26655.1 - 1.2e-20 74.0 0.0 2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CAR26655.1 - 3.2e-08 33.3 0.0 5.6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CAR26655.1 - 2.1e-06 28.3 0.0 3.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR26655.1 - 1.7e-05 24.7 0.0 2.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CAR26655.1 - 3.9e-05 22.8 0.0 8.3e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 CAR26655.1 - 4.7e-05 24.1 0.0 8.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CAR26655.1 - 8.1e-05 22.2 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CAR26655.1 - 8.9e-05 23.1 0.0 0.00018 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CAR26655.1 - 0.0027 17.1 0.0 0.0059 16.0 0.0 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_31 PF13847.6 CAR26655.1 - 0.0073 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CAR26655.1 - 0.19 11.5 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Allantoicase PF03561.15 CAR26656.1 - 6.6e-87 288.8 0.5 3.5e-48 163.3 0.0 2.9 2 1 0 2 2 2 2 Allantoicase repeat ApoO PF09769.9 CAR26657.1 - 7.4e-32 110.1 0.1 1.4e-31 109.2 0.0 1.4 2 0 0 2 2 2 1 Apolipoprotein O Globin PF00042.22 CAR26658.1 - 1.6e-09 38.3 0.0 4.1e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 CAR26658.1 - 1.8e-09 37.8 0.0 3.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CAR26658.1 - 4.2e-07 30.6 0.0 1.6e-06 28.7 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 CAR26658.1 - 0.0018 18.2 0.2 0.0046 16.9 0.2 1.6 1 1 0 1 1 1 1 Protoglobin Scm3 PF10384.9 CAR26658.1 - 0.03 14.1 1.0 0.055 13.2 1.0 1.4 1 0 0 1 1 1 0 Centromere protein Scm3 RTT107_BRCT_6 PF16771.5 CAR26659.1 - 3e-36 124.0 0.3 1.3e-35 122.0 0.3 2.2 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain RTT107_BRCT_5 PF16770.5 CAR26659.1 - 2.9e-24 84.8 0.2 2e-22 78.9 0.0 3.0 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 CAR26659.1 - 1.3e-19 69.9 0.1 4.8e-12 45.6 0.0 4.0 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.26 CAR26659.1 - 1.2e-16 60.9 11.5 4.7e-05 23.7 0.0 5.2 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CAR26659.1 - 8.6e-14 51.7 1.3 0.0026 18.2 0.2 4.9 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CAR26659.1 - 0.0074 16.6 0.4 18 5.7 0.0 4.0 4 0 0 4 4 4 1 DNA ligase 3 BRCT domain zf-C4 PF00105.18 CAR26659.1 - 0.21 12.0 0.6 0.52 10.8 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C4 type (two domains) AA_permease_2 PF13520.6 CAR26660.1 - 3.4e-65 220.5 46.7 4.1e-65 220.3 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAR26660.1 - 4.9e-18 65.0 38.4 7.8e-18 64.3 38.4 1.2 1 0 0 1 1 1 1 Amino acid permease GWT1 PF06423.12 CAR26660.1 - 1.2 9.3 0.0 1.2 9.3 0.0 3.1 2 1 2 4 4 4 0 GWT1 Ank_2 PF12796.7 CAR26662.1 - 3.3e-31 107.7 0.3 3.6e-13 49.9 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAR26662.1 - 1e-22 79.9 1.0 0.0023 18.2 0.0 6.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 CAR26662.1 - 1.2e-20 73.6 0.4 3.8e-07 30.5 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.19 CAR26662.1 - 2e-20 74.1 16.5 9.3e-08 32.4 0.2 3.2 1 1 2 3 3 3 3 SPX domain Ank_3 PF13606.6 CAR26662.1 - 2.6e-19 67.3 0.2 0.0016 18.8 0.0 6.1 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CAR26662.1 - 3.3e-19 68.4 3.6 0.0091 16.4 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat GDPD PF03009.17 CAR26662.1 - 0.0084 15.9 0.0 0.037 13.8 0.0 2.1 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_4 PF13637.6 CAR26663.1 - 1.1e-31 108.7 0.2 7.7e-06 26.4 0.0 5.6 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR26663.1 - 1.7e-31 108.6 0.0 1.8e-13 50.8 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAR26663.1 - 5.3e-29 99.9 1.0 2e-09 37.5 0.0 4.9 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAR26663.1 - 8.2e-29 96.5 1.2 0.0003 21.0 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CAR26663.1 - 1.2e-25 88.7 1.8 1.1e-06 28.8 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.8 CAR26663.1 - 0.022 14.3 0.1 4.3 7.0 0.0 2.8 3 0 0 3 3 3 0 Shal-type voltage-gated potassium channels, N-terminal zf-SAP30 PF13866.6 CAR26663.1 - 0.11 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 SAP30 zinc-finger Band_7 PF01145.25 CAR26664.1 - 6.4e-20 71.9 0.5 1e-19 71.2 0.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family COMPASS-Shg1 PF05205.12 CAR26664.1 - 0.76 10.5 3.8 15 6.4 0.2 2.2 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Spo12 PF05032.12 CAR26665.1 - 3.3e-19 68.5 4.6 3.3e-19 68.5 4.6 1.8 2 0 0 2 2 2 1 Spo12 family SMI1_KNR4 PF09346.10 CAR26666.1 - 9.6e-32 110.2 0.0 1.6e-30 106.2 0.0 3.1 1 1 2 3 3 3 1 SMI1 / KNR4 family (SUKH-1) DIE2_ALG10 PF04922.12 CAR26667.1 - 1.8e-109 366.7 29.8 1.8e-109 366.7 29.8 2.1 3 0 0 3 3 3 1 DIE2/ALG10 family Pex24p PF06398.11 CAR26669.1 - 3.1e-70 237.0 0.7 6.2e-70 236.0 0.7 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Reticulon PF02453.17 CAR26669.1 - 0.013 15.5 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 Reticulon PRT_C PF08372.10 CAR26669.1 - 0.061 13.1 1.5 0.074 12.8 0.3 1.7 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal DUF639 PF04842.12 CAR26669.1 - 0.074 12.5 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF2208 PF09973.9 CAR26669.1 - 0.094 12.3 3.7 0.12 12.0 0.1 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2208) NAAA-beta PF15508.6 CAR26669.1 - 0.13 12.6 0.0 0.41 11.0 0.0 1.9 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase WD40 PF00400.32 CAR26670.1 - 6e-14 52.2 3.3 0.00015 22.5 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR26670.1 - 3.2e-06 27.4 0.4 1.3 9.4 0.0 4.0 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAR26670.1 - 0.0013 18.1 0.0 0.54 9.5 0.0 2.8 3 0 0 3 3 3 2 WD40-like domain Frtz PF11768.8 CAR26670.1 - 0.054 11.8 0.0 2 6.6 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40 PF00400.32 CAR26671.1 - 0.00064 20.5 0.0 2.1 9.4 0.0 3.7 2 1 1 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CAR26671.1 - 0.0031 16.5 0.5 0.24 10.3 0.0 3.1 3 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 CAR26671.1 - 0.0047 17.2 0.0 4.8 7.5 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ILVD_EDD PF00920.21 CAR26673.1 - 2.6e-207 689.6 0.1 3e-207 689.3 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family SKG6 PF08693.10 CAR26674.1 - 1.4e-09 37.2 3.0 2.2e-09 36.5 3.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF3377 PF11857.8 CAR26674.1 - 0.0022 17.9 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) TMEM154 PF15102.6 CAR26674.1 - 0.018 14.9 0.0 0.08 12.8 0.0 2.1 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.6 CAR26674.1 - 0.029 14.1 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF1180 PF06679.12 CAR26674.1 - 0.083 13.3 0.8 0.27 11.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF2207 PF09972.9 CAR26674.1 - 0.14 10.9 0.0 0.33 9.7 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FixQ PF05545.11 CAR26674.1 - 0.15 12.0 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Shisa PF13908.6 CAR26674.1 - 1.8 8.8 0.0 1.8 8.8 0.0 3.7 3 1 0 3 3 3 0 Wnt and FGF inhibitory regulator Ribosomal_S4 PF00163.19 CAR26675.1 - 2.1e-12 47.8 1.5 3.6e-12 47.0 1.4 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 CAR26675.1 - 2.1e-10 40.1 0.0 5.1e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.11 CAR26675.1 - 0.033 12.8 0.1 0.039 12.6 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Pox_A_type_inc PF04508.12 CAR26675.1 - 0.047 13.6 2.1 0.96 9.4 0.5 2.8 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Ribosomal_L6 PF00347.23 CAR26676.1 - 1.2e-25 89.9 1.7 9.7e-16 58.2 0.1 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L3 PF00297.22 CAR26677.1 - 6.2e-17 61.6 0.7 7.1e-15 54.8 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 CRM1_C PF08767.11 CAR26678.1 - 1.8e-130 434.8 4.4 1.8e-130 434.8 4.4 2.8 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 CAR26678.1 - 1.2e-36 126.1 4.1 1.2e-36 126.1 4.1 3.7 5 0 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CAR26678.1 - 6.7e-32 109.0 1.8 1.8e-31 107.6 1.8 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CAR26678.1 - 1.1e-28 99.1 0.5 1.1e-28 99.1 0.5 3.1 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 CAR26678.1 - 5.2e-16 58.3 0.6 5.2e-15 55.1 0.1 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 CAR26678.1 - 6.8e-16 57.5 0.4 6.8e-16 57.5 0.4 2.1 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat DUF3385 PF11865.8 CAR26678.1 - 0.061 13.2 4.1 0.24 11.3 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) MerR_2 PF13591.6 CAR26678.1 - 0.087 12.7 0.3 0.51 10.2 0.3 2.4 1 0 0 1 1 1 0 MerR HTH family regulatory protein V-ATPase_H_C PF11698.8 CAR26678.1 - 0.096 12.8 1.2 2.1 8.5 0.1 3.3 2 0 0 2 2 2 0 V-ATPase subunit H Tom6 PF17112.5 CAR26679.1 - 2.3e-27 94.2 2.6 2.8e-27 93.9 2.6 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal DEAD PF00270.29 CAR26680.1 - 1.8e-37 128.8 0.6 4.1e-37 127.7 0.2 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR26680.1 - 2e-28 98.9 0.0 4.7e-28 97.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CAR26680.1 - 0.004 16.5 10.3 0.036 13.4 0.1 3.2 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 CAR26680.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Spore_coat_CotO PF14153.6 CAR26680.1 - 0.11 12.4 11.3 0.19 11.6 11.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO TetR_C_11 PF16859.5 CAR26680.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Tim54 PF11711.8 CAR26680.1 - 0.25 10.1 6.8 0.42 9.4 6.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CobT PF06213.12 CAR26680.1 - 3.9 6.8 14.6 6.3 6.1 14.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT XRN_M PF17846.1 CAR26681.1 - 2.2e-129 432.3 15.9 2.8e-93 313.3 6.1 2.8 2 1 1 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 CAR26681.1 - 1.5e-98 329.0 0.0 1.5e-98 329.0 0.0 2.5 2 1 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Arabino_trans_C PF14896.6 CAR26681.1 - 0.53 9.2 6.6 1.2 8.1 6.6 1.5 1 0 0 1 1 1 0 EmbC C-terminal domain Med30 PF11315.8 CAR26682.1 - 0.04 14.1 0.0 0.084 13.1 0.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 30 DUF2935 PF11155.8 CAR26682.1 - 0.076 13.3 0.1 13 6.1 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) RTA1 PF04479.13 CAR26683.1 - 1.2e-68 230.8 11.1 2e-68 230.1 11.1 1.4 1 0 0 1 1 1 1 RTA1 like protein Acyltransferase PF01553.21 CAR26684.1 - 1.1e-05 25.0 0.0 8.4e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase PapC_C PF13953.6 CAR26684.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 PapC C-terminal domain TRAPP PF04051.16 CAR26685.1 - 2.4e-31 108.4 0.0 3.5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dsl1_N PF11988.8 CAR26685.1 - 0.049 12.6 0.0 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal Nro1 PF12753.7 CAR26686.1 - 2e-168 560.6 25.2 2.2e-168 560.5 25.2 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 MerR_2 PF13591.6 CAR26686.1 - 0.023 14.6 0.1 0.1 12.5 0.1 2.2 1 0 0 1 1 1 0 MerR HTH family regulatory protein CdiI_2 PF18593.1 CAR26686.1 - 0.38 11.4 0.1 0.38 11.4 0.1 3.2 2 1 0 2 2 2 0 CdiI immunity protein TP_methylase PF00590.20 CAR26687.1 - 6.1e-42 144.0 0.2 9.4e-42 143.4 0.2 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 CAR26687.1 - 4.5e-11 43.1 0.0 1.1e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 CAR26687.1 - 1.7e-09 36.9 0.3 4.4e-09 35.6 0.3 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 CAR26687.1 - 0.02 14.5 0.1 4.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal DUF2199 PF09965.9 CAR26687.1 - 0.079 13.0 0.6 0.17 12.0 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2199) Hydrolase_like PF13242.6 CAR26688.1 - 3.1e-26 91.2 0.0 5.7e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 CAR26688.1 - 3.5e-24 84.8 0.0 6.3e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR26688.1 - 0.0045 17.3 0.0 0.4 10.9 0.0 3.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAR26688.1 - 0.0048 17.0 0.1 0.12 12.4 0.0 2.8 3 1 1 4 4 4 1 Haloacid dehalogenase-like hydrolase REC1 PF18501.1 CAR26688.1 - 0.091 12.6 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Alpha helical recognition lobe domain zf-AN1 PF01428.16 CAR26689.1 - 2e-09 37.4 12.7 3.6e-09 36.7 12.7 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger MutL PF13941.6 CAR26689.1 - 0.1 11.1 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 MutL protein C5HCH PF17982.1 CAR26689.1 - 1 9.6 9.1 1.8 8.8 9.1 1.4 1 0 0 1 1 1 0 NSD Cys-His rich domain Androgen_recep PF02166.16 CAR26689.1 - 1.4 7.7 7.4 4.8 5.9 3.7 2.0 1 1 0 2 2 2 0 Androgen receptor SUIM_assoc PF16619.5 CAR26689.1 - 2.9 8.0 12.4 3.7 7.7 4.6 2.2 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CIAPIN1 PF05093.13 CAR26690.1 - 6.1e-38 129.4 5.7 6.1e-38 129.4 5.7 2.2 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 CAR26690.1 - 3.6e-28 98.4 0.0 5.7e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Dicty_REP PF05086.12 CAR26690.1 - 0.017 13.1 5.2 0.021 12.8 5.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Flavoprotein PF02441.19 CAR26691.1 - 2.4e-51 173.6 0.0 5.5e-51 172.5 0.0 1.6 1 1 0 1 1 1 1 Flavoprotein TFIIA PF03153.13 CAR26691.1 - 1.8e-13 51.3 31.2 1.8e-13 51.3 31.2 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PPP4R2 PF09184.11 CAR26691.1 - 0.0032 17.1 15.5 0.0032 17.1 15.5 3.1 3 0 0 3 3 3 1 PPP4R2 DUF2052 PF09747.9 CAR26691.1 - 0.029 14.5 25.0 0.025 14.7 9.5 2.8 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) DUF3474 PF11960.8 CAR26691.1 - 0.25 11.5 3.5 0.61 10.3 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) Connexin PF00029.19 CAR26691.1 - 0.9 9.2 8.2 8.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Connexin DUF4746 PF15928.5 CAR26691.1 - 1.2 8.5 20.0 1.3 8.4 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Serinc PF03348.15 CAR26691.1 - 7 5.5 7.3 25 3.6 0.1 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) PIN_6 PF17146.4 CAR26692.1 - 5.1e-32 110.2 0.0 1.2e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CAR26692.1 - 7.3e-24 83.7 0.2 1.8e-23 82.5 0.1 1.7 1 1 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 CAR26692.1 - 0.084 13.0 0.4 0.19 11.9 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Ndc1_Nup PF09531.10 CAR26692.1 - 0.11 11.2 4.9 0.15 10.7 4.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zinc_ribbon_9 PF14369.6 CAR26692.1 - 0.16 12.2 0.5 0.36 11.1 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon Miga PF10265.9 CAR26692.1 - 0.49 9.3 4.4 0.73 8.7 4.4 1.3 1 0 0 1 1 1 0 Mitoguardin ALMT PF11744.8 CAR26692.1 - 5.2 5.8 6.8 7.8 5.2 6.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter NPR3 PF03666.13 CAR26692.1 - 6.6 5.4 17.3 12 4.6 17.3 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 CAR26692.1 - 7 5.3 17.9 12 4.6 17.9 1.4 1 0 0 1 1 1 0 Presenilin Red1 PF07964.11 CAR26692.1 - 9.2 4.4 25.1 13 3.8 25.1 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Hid1 PF12722.7 CAR26692.1 - 9.8 4.2 14.4 13 3.8 14.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SGS PF05002.15 CAR26693.1 - 5.3e-30 103.4 1.8 5.3e-30 103.4 1.8 2.3 2 0 0 2 2 2 1 SGS domain CS PF04969.16 CAR26693.1 - 1.3e-11 45.3 0.4 2.4e-11 44.5 0.4 1.5 1 0 0 1 1 1 1 CS domain MAP65_ASE1 PF03999.12 CAR26694.1 - 4.9e-114 382.2 24.4 8.3e-114 381.5 24.4 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF1870 PF08965.10 CAR26694.1 - 0.025 14.6 0.1 0.14 12.2 0.1 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) Spore_III_AB PF09548.10 CAR26694.1 - 0.043 13.9 0.1 0.043 13.9 0.1 3.3 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Retrotrans_gag PF03732.17 CAR26694.1 - 0.051 13.9 1.0 5.8 7.3 0.7 3.3 2 0 0 2 2 2 0 Retrotransposon gag protein NLRC4_HD PF17889.1 CAR26694.1 - 0.1 12.9 2.6 0.33 11.3 0.1 3.3 2 1 0 3 3 3 0 NLRC4 helical domain Virulence_fact PF13769.6 CAR26694.1 - 0.14 12.4 0.1 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 Virulence factor Bacillus_HBL PF05791.11 CAR26694.1 - 0.23 11.3 10.4 5.8 6.7 0.3 3.9 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) LUC7 PF03194.15 CAR26694.1 - 0.34 10.5 4.8 8.9 5.9 4.4 2.9 1 1 0 1 1 1 0 LUC7 N_terminus DUF2340 PF10209.9 CAR26695.1 - 2.2e-53 179.8 1.7 2.5e-53 179.6 1.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF676 PF05057.14 CAR26696.1 - 3.2e-49 167.4 0.0 4.9e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CAR26696.1 - 2.4e-05 24.2 0.1 6.4e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 CAR26696.1 - 0.013 15.4 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 CAR26696.1 - 0.17 12.5 0.0 0.4 11.3 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sld7_N PF18636.1 CAR26697.1 - 2.7e-40 137.5 0.4 4.7e-40 136.8 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial morphogenesis protein SLD7 N-terminal domain Sld7_C PF18596.1 CAR26697.1 - 6.8e-24 83.8 0.0 1.7e-23 82.5 0.0 1.7 1 1 0 1 1 1 1 Sld7 C-terminal domain Pkinase PF00069.25 CAR26698.1 - 9.5e-57 192.3 0.0 1.2e-56 192.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR26698.1 - 8.2e-16 58.1 0.0 1.3e-15 57.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR26698.1 - 3.1e-07 30.6 0.0 1.5e-06 28.3 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CAR26698.1 - 0.031 13.9 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CAR26698.1 - 0.047 12.5 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CAR26698.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3K_1B_p101 PF10486.9 CAR26699.1 - 0.26 9.0 2.6 0.32 8.7 2.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ribosomal_L3 PF00297.22 CAR26700.1 - 3.5e-186 618.5 8.4 4e-186 618.4 8.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Tho1_MOS11_C PF18592.1 CAR26700.1 - 0.13 12.1 2.8 0.42 10.4 0.2 2.8 3 0 0 3 3 3 0 Tho1/MOS11 C-terminal domain zf-HC5HC2H PF13771.6 CAR26701.1 - 0.0046 17.2 2.7 0.0098 16.1 2.7 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CAR26701.1 - 0.055 13.6 2.0 0.11 12.7 2.0 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain Ecl1 PF12855.7 CAR26701.1 - 0.062 14.5 1.5 0.49 11.5 0.1 2.1 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins FtsH_ext PF06480.15 CAR26701.1 - 0.089 13.1 1.4 0.21 11.9 1.6 1.5 1 1 1 2 2 2 0 FtsH Extracellular Nore1-SARAH PF16517.5 CAR26701.1 - 0.38 10.7 2.7 0.21 11.5 0.5 1.7 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Cytochrom_C1 PF02167.15 CAR26702.1 - 1.2e-94 316.1 0.0 1.5e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CAR26702.1 - 0.0013 19.0 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CAR26702.1 - 0.0086 17.2 0.1 0.032 15.4 0.1 2.0 2 1 0 2 2 2 1 Cytochrome c zf-H2C2_2 PF13465.6 CAR26703.1 - 1.6e-18 66.2 24.3 1.7e-09 37.7 0.9 4.8 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 CAR26703.1 - 6.3e-15 54.7 37.6 1.9e-05 24.9 0.1 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR26703.1 - 3.3e-08 33.7 34.0 0.0016 19.1 0.1 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.7 CAR26703.1 - 1.1e-05 25.7 13.2 0.02 15.3 0.1 4.8 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CAR26703.1 - 0.038 14.3 14.5 0.23 11.8 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 CAR26703.1 - 0.051 13.7 1.3 0.1 12.7 0.1 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger zf-Di19 PF05605.12 CAR26703.1 - 2 8.8 11.4 4.1 7.8 0.9 2.7 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-DBF PF07535.12 CAR26703.1 - 3.6 7.8 9.7 18 5.6 0.4 3.9 3 0 0 3 3 3 0 DBF zinc finger zf-C2H2_6 PF13912.6 CAR26703.1 - 9.7 6.3 25.6 2.9 8.0 0.3 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger KRAB PF01352.27 CAR26704.1 - 0.034 13.8 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 KRAB box TRAPP PF04051.16 CAR26705.1 - 7e-30 103.7 0.0 1.6e-29 102.5 0.0 1.6 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component zf-Mss51 PF13824.6 CAR26705.1 - 0.082 13.0 0.1 0.23 11.6 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 SH3_1 PF00018.28 CAR26706.1 - 1.3e-21 75.9 0.2 2.4e-10 39.8 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 CAR26706.1 - 1.4e-19 69.7 0.8 1.4e-09 37.7 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 CAR26706.1 - 3.6e-19 68.8 0.4 3.6e-19 68.8 0.4 3.1 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 CAR26706.1 - 3.4e-11 42.7 0.1 4.6e-07 29.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 CAR26706.1 - 0.0053 17.0 0.3 3.4 8.0 0.1 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain DUF2271 PF10029.9 CAR26706.1 - 0.059 13.0 1.4 8.3 6.1 0.1 2.5 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2271) Tox-HNH-HHH PF15637.6 CAR26706.1 - 2 8.6 5.0 21 5.3 0.4 2.8 2 1 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif IFT57 PF10498.9 CAR26706.1 - 7.8 5.3 19.1 0.15 11.0 8.5 2.6 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 DUF2417 PF10329.9 CAR26707.1 - 1.3e-84 283.4 5.7 1.7e-84 282.9 5.7 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 CAR26707.1 - 5.4e-11 42.6 0.0 1.8e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR26707.1 - 0.00052 20.7 0.0 0.00074 20.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CAR26707.1 - 0.051 13.7 0.0 0.094 12.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain FHA PF00498.26 CAR26708.1 - 4.9e-14 52.4 0.0 1.1e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 CAR26708.1 - 1.1e-11 44.2 8.5 2e-11 43.4 8.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CAR26708.1 - 1.2e-07 31.9 10.9 2e-07 31.2 10.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CAR26708.1 - 0.00018 21.7 6.3 0.00038 20.7 6.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CAR26708.1 - 0.00056 19.7 10.6 0.00099 18.9 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 CAR26708.1 - 0.0017 18.6 0.0 0.0045 17.3 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_2 PF13923.6 CAR26708.1 - 0.0045 16.8 10.6 0.0079 16.0 10.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CAR26708.1 - 0.0068 16.4 4.2 0.013 15.6 4.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CAR26708.1 - 0.021 14.8 9.2 0.042 13.9 9.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CAR26708.1 - 0.022 14.7 12.0 0.037 14.0 12.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Sec_GG PF07549.14 CAR26708.1 - 0.075 12.5 0.2 0.19 11.2 0.2 1.7 1 0 0 1 1 1 0 SecD/SecF GG Motif Malate_synthase PF01274.22 CAR26709.1 - 2.5e-216 719.0 0.0 3e-216 718.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase NMT1 PF09084.11 CAR26710.1 - 6.8e-10 39.3 0.0 9.9e-10 38.7 0.0 1.3 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 CAR26710.1 - 1.3e-08 34.9 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family Phosphonate-bd PF12974.7 CAR26710.1 - 1.3e-08 34.7 0.0 1.8e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.20 CAR26710.1 - 3.7e-05 23.3 0.0 6.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 LysR_substrate PF03466.20 CAR26710.1 - 0.016 14.6 0.0 0.02 14.2 0.0 1.3 1 1 0 1 1 1 0 LysR substrate binding domain VitK2_biosynth PF02621.14 CAR26710.1 - 0.21 11.0 0.2 0.76 9.2 0.0 1.9 2 0 0 2 2 2 0 Menaquinone biosynthesis DCP2 PF05026.13 CAR26711.1 - 8.4e-25 86.9 1.0 2.1e-24 85.7 1.0 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 CAR26711.1 - 1.2e-13 51.2 0.0 2.9e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Orthopox_F6 PF06601.12 CAR26711.1 - 0.15 12.3 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Orthopoxvirus F6 protein CTU2 PF10288.9 CAR26712.1 - 5.3e-22 78.2 1.8 3.6e-21 75.5 0.1 2.5 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 HscB_4_cys PF18256.1 CAR26712.1 - 0.011 15.5 1.3 0.027 14.3 1.3 1.7 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Pcc1 PF09341.10 CAR26713.1 - 3.2e-18 65.6 0.0 3.5e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 PIN_4 PF13638.6 CAR26714.1 - 5.9e-14 52.5 0.2 5.9e-14 52.5 0.2 2.5 2 1 0 2 2 2 1 PIN domain PEPCK_ATP PF01293.20 CAR26716.1 - 2.8e-218 725.3 0.0 3.3e-218 725.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 CAR26716.1 - 0.025 14.7 0.0 0.087 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CAR26716.1 - 0.029 14.8 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 CAR26716.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 CAR26716.1 - 0.13 12.0 0.1 0.38 10.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CAR26716.1 - 0.18 11.3 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain PTPA PF03095.15 CAR26717.1 - 8.5e-103 343.9 0.0 1.6e-102 343.0 0.0 1.4 2 0 0 2 2 2 1 Phosphotyrosyl phosphate activator (PTPA) protein Peptidase_C39 PF03412.15 CAR26717.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase C39 family Usp PF00582.26 CAR26718.1 - 0.0015 19.0 0.9 0.02 15.4 0.0 2.2 2 0 0 2 2 2 1 Universal stress protein family Nop14 PF04147.12 CAR26718.1 - 0.0019 16.5 1.0 0.0031 15.8 1.0 1.3 1 0 0 1 1 1 1 Nop14-like family DUF2722 PF10846.8 CAR26718.1 - 0.031 13.2 2.0 0.043 12.8 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DNA_pol_phi PF04931.13 CAR26718.1 - 1.1 7.3 9.6 1.7 6.7 9.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi DAO PF01266.24 CAR26719.1 - 1.1e-49 170.0 0.0 1.6e-49 169.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CAR26719.1 - 2e-41 140.8 0.0 4.3e-41 139.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CAR26719.1 - 8.9e-13 48.1 2.2 3.8e-12 46.0 2.2 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CAR26719.1 - 3.6e-09 36.5 0.8 6.1e-05 22.5 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CAR26719.1 - 0.00017 21.0 1.2 0.0029 16.9 1.3 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CAR26719.1 - 0.00032 20.0 0.2 0.00092 18.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CAR26719.1 - 0.0011 18.1 0.9 0.06 12.4 0.4 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 CAR26719.1 - 0.0077 15.0 0.6 0.015 14.1 0.6 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 CAR26719.1 - 0.012 14.8 0.4 0.12 11.6 0.1 2.1 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 CAR26719.1 - 0.013 15.7 1.0 0.047 13.9 1.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CAR26719.1 - 0.067 12.4 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CAR26719.1 - 0.076 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 CAR26719.1 - 2.4 8.0 4.2 1.3 8.9 1.0 2.2 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UCH PF00443.29 CAR26720.1 - 4.8e-57 193.4 7.5 4.8e-57 193.4 7.5 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR26720.1 - 9.9e-15 54.9 14.0 1.6e-12 47.7 14.0 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rubredoxin_2 PF18073.1 CAR26720.1 - 4.2 7.2 5.1 21 5.0 1.1 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain Myb_DNA-bind_6 PF13921.6 CAR26721.1 - 1.9e-32 111.3 3.0 1e-11 44.9 0.2 3.7 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CAR26721.1 - 4.5e-32 110.0 12.0 1.1e-13 51.1 0.1 3.6 3 1 0 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CAR26721.1 - 3e-05 24.0 1.3 0.45 10.6 0.0 3.8 3 1 0 4 4 4 2 SLIDE SANT_DAMP1_like PF16282.5 CAR26721.1 - 0.0031 17.7 1.3 8.6 6.6 0.1 3.6 3 1 1 4 4 4 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 CAR26721.1 - 0.044 13.9 0.9 5.1 7.2 0.3 3.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain NOA36 PF06524.12 CAR26721.1 - 2.9 7.1 7.1 6.5 6.0 7.1 1.5 1 0 0 1 1 1 0 NOA36 protein DUF1748 PF08520.10 CAR26722.1 - 9e-28 96.0 0.0 9.9e-28 95.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Coa1 PF08695.10 CAR26723.1 - 1.2e-40 137.8 0.0 1.5e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Sipho_tail PF05709.11 CAR26723.1 - 0.095 12.1 0.0 0.11 11.9 0.0 1.0 1 0 0 1 1 1 0 Phage tail protein Flu_B_M2 PF04772.12 CAR26723.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) Peptidase_M42 PF05343.14 CAR26724.1 - 0.026 13.5 0.1 0.044 12.8 0.1 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase SKG6 PF08693.10 CAR26724.1 - 0.061 12.7 0.4 0.2 11.1 0.4 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FH2 PF02181.23 CAR26725.1 - 2.5e-73 247.4 13.7 2.5e-73 247.4 13.7 2.7 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CAR26725.1 - 7.6e-13 48.4 0.3 7.6e-13 48.4 0.3 3.0 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain Thiolase_N PF00108.23 CAR26726.1 - 2.3e-75 253.4 0.0 3e-75 253.0 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CAR26726.1 - 9.6e-49 164.1 0.4 1.6e-48 163.4 0.4 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CAR26726.1 - 6.8e-05 22.6 0.0 0.00021 21.0 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain CDC45 PF02724.14 CAR26727.1 - 0.045 12.1 9.0 0.048 11.9 9.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 CAR26727.1 - 0.062 11.9 17.3 0.07 11.7 17.3 1.1 1 0 0 1 1 1 0 Macoilin family Pneumo_att_G PF05539.11 CAR26727.1 - 0.32 10.5 10.8 0.41 10.2 10.8 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Presenilin PF01080.17 CAR26727.1 - 1 8.1 15.7 1.3 7.8 15.7 1.2 1 0 0 1 1 1 0 Presenilin Epimerase PF01370.21 CAR26728.1 - 1.5e-19 70.5 0.0 2.3e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAR26728.1 - 2.9e-11 43.4 0.0 3.1e-10 40.0 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CAR26728.1 - 1.2e-10 40.9 0.0 1.7e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 CAR26728.1 - 4.1e-07 29.6 0.0 1.3e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 CAR26728.1 - 1.1e-06 28.7 0.0 2.9e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CAR26728.1 - 9.6e-06 24.9 0.0 0.032 13.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 CAR26728.1 - 2.3e-05 24.1 0.1 4.4e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 CAR26728.1 - 0.00016 20.9 0.0 0.01 15.0 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CAR26728.1 - 0.0007 18.8 0.0 0.038 13.1 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 CAR26728.1 - 0.0051 17.1 0.0 0.009 16.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 CAR26728.1 - 0.0056 16.6 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 CAR26728.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Catalase PF00199.19 CAR26729.1 - 7.6e-180 598.0 0.0 9.5e-180 597.7 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CAR26729.1 - 8.4e-11 41.9 0.0 1.8e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive MFS_1 PF07690.16 CAR26730.1 - 5.6e-32 111.0 28.9 5.6e-32 111.0 28.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR26730.1 - 0.00017 20.1 3.0 0.00026 19.6 3.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CAR26730.1 - 0.16 10.2 19.8 0.033 12.5 7.5 3.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Cornifin PF02389.15 CAR26731.1 - 2.2e-05 24.7 1.1 2.2e-05 24.7 1.1 2.2 2 0 0 2 2 2 1 Cornifin (SPRR) family MFS_1 PF07690.16 CAR26732.1 - 2.7e-07 29.8 3.7 8e-07 28.3 4.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily SBF PF01758.16 CAR26733.1 - 1.4e-52 178.2 13.0 1.4e-52 178.2 13.0 1.9 3 1 0 3 3 3 1 Sodium Bile acid symporter family Sortilin-Vps10 PF15902.5 CAR26734.1 - 1e-19 70.7 0.0 2.1e-19 69.6 0.0 1.5 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CAR26734.1 - 1.7e-06 28.5 0.1 2.4e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CAR26734.1 - 8.7e-05 22.0 3.1 0.13 12.4 0.0 3.4 3 0 0 3 3 3 2 BNR/Asp-box repeat Nitr_red_alph_N PF14710.6 CAR26734.1 - 0.035 14.6 0.1 0.12 12.9 0.1 1.9 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal CHB_HEX_C PF03174.13 CAR26734.1 - 0.17 11.9 0.0 1 9.4 0.0 2.2 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain DUP PF00674.18 CAR26735.1 - 1e-08 35.2 0.3 1e-08 35.2 0.3 2.5 3 0 0 3 3 3 1 DUP family Aminotran_3 PF00202.21 CAR26736.1 - 3.1e-99 332.4 0.0 5.5e-99 331.6 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CAR26736.1 - 9.8e-05 21.8 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Peptidase_M16_C PF05193.21 CAR26736.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 1 0 1 1 1 0 Peptidase M16 inactive domain AAA_26 PF13500.6 CAR26737.1 - 6.9e-39 133.7 0.0 8.8e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CAR26737.1 - 0.13 12.3 0.0 6.9 6.7 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUP PF00674.18 CAR26738.1 - 7.8e-09 35.6 0.9 7.8e-09 35.6 0.9 2.3 2 0 0 2 2 2 1 DUP family DUP PF00674.18 CAR26740.1 - 5.8e-42 142.0 5.1 5.6e-23 81.0 2.1 2.4 2 0 0 2 2 2 2 DUP family PNTB PF02233.16 CAR26740.1 - 0.14 11.1 0.1 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit BioY PF02632.14 CAR26740.1 - 0.33 11.0 4.4 0.76 9.8 0.3 2.2 2 0 0 2 2 2 0 BioY family DUF1445 PF07286.12 CAR26742.1 - 3.2e-54 182.8 0.0 4.1e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Transp_cyt_pur PF02133.15 CAR26743.1 - 1.4e-81 274.6 23.3 1.6e-81 274.3 23.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Bac_luciferase PF00296.20 CAR26744.1 - 1e-51 176.2 0.0 1.5e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Sugar_tr PF00083.24 CAR26745.1 - 3e-79 267.0 27.5 3.7e-79 266.7 27.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR26745.1 - 4e-29 101.7 32.8 4e-29 101.7 32.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ELFV_dehydrog PF00208.21 CAR26746.1 - 8.2e-81 271.3 4.0 1e-80 271.0 4.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CAR26746.1 - 7.7e-48 161.7 0.0 1.8e-47 160.5 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 CAR26746.1 - 0.092 13.2 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Alb1 PF09135.11 CAR26747.1 - 5.5e-26 91.5 11.2 5.5e-26 91.5 11.2 1.8 2 0 0 2 2 2 1 Alb1 Calreticulin PF00262.18 CAR26748.1 - 9.9e-132 439.2 1.7 1.2e-131 439.0 1.7 1.1 1 0 0 1 1 1 1 Calreticulin family Aldedh PF00171.22 CAR26749.1 - 1.4e-180 600.8 0.2 1.5e-180 600.6 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LRR_8 PF13855.6 CAR26750.1 - 6.1e-15 54.7 35.8 0.00025 20.7 1.5 6.4 4 2 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 CAR26750.1 - 2.5e-14 53.1 43.6 0.0016 18.8 1.0 7.5 4 3 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CAR26750.1 - 3.4e-07 29.8 28.4 0.3 11.3 0.2 8.5 8 0 0 8 8 8 4 Leucine Rich repeat LRR_9 PF14580.6 CAR26750.1 - 0.0017 17.9 12.6 0.086 12.3 0.2 4.2 2 1 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 CAR26750.1 - 0.0061 16.9 34.1 5.3 8.0 1.1 9.7 5 3 2 7 7 7 3 Leucine Rich Repeat DivIC PF04977.15 CAR26751.1 - 3.2 7.6 8.2 9.5 6.1 8.2 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF4175 PF13779.6 CAR26751.1 - 9.3 4.0 15.2 19 3.0 15.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Kelch_6 PF13964.6 CAR26752.1 - 5.6e-10 39.1 8.7 0.14 12.5 0.1 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 CAR26752.1 - 7.8e-10 38.5 5.1 0.19 11.7 0.0 6.5 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.25 CAR26752.1 - 3.2e-08 33.0 13.4 0.0079 15.8 0.3 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CAR26752.1 - 2.5e-07 30.4 14.5 0.038 14.0 0.2 6.8 7 0 0 7 7 7 2 Kelch motif Kelch_4 PF13418.6 CAR26752.1 - 2.3e-06 27.5 15.2 0.0017 18.3 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CAR26752.1 - 0.0015 18.8 6.0 0.24 11.8 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain ABM PF03992.16 CAR26752.1 - 0.13 12.4 0.3 0.24 11.5 0.3 1.4 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase GDI PF00996.18 CAR26753.1 - 6.9e-44 150.1 0.0 3.4e-43 147.8 0.0 1.8 1 1 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CAR26753.1 - 0.0064 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CAR26753.1 - 0.06 12.6 0.0 0.12 11.5 0.0 1.6 1 1 0 1 1 1 0 FAD binding domain Glyco_hydro_2_N PF02837.18 CAR26753.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Ribosomal_L7Ae PF01248.26 CAR26754.1 - 3.7e-21 74.7 0.4 4.7e-21 74.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.12 CAR26754.1 - 0.023 15.0 0.1 0.045 14.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Rad1 PF02144.16 CAR26755.1 - 7.9e-63 212.1 0.6 1.2e-62 211.5 0.6 1.3 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Peroxin-22 PF12827.7 CAR26756.1 - 5.2e-29 100.5 0.0 6.6e-29 100.1 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family CH PF00307.31 CAR26757.1 - 2e-16 60.1 0.0 3.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain AMP-binding PF00501.28 CAR26758.1 - 4e-88 295.8 0.0 5.1e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAR26758.1 - 3.8e-23 82.2 0.1 4.9e-22 78.7 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CAR26758.1 - 2.6e-17 62.5 1.0 5.5e-17 61.4 1.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus TRP PF06011.12 CAR26759.1 - 7.6e-155 515.8 34.0 9.2e-155 515.5 34.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CAR26759.1 - 1.4e-39 135.6 0.8 2.3e-39 135.0 0.8 1.3 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 CAR26759.1 - 1.2e-05 25.7 0.1 2.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 ML domain KLRAQ PF10205.9 CAR26759.1 - 0.035 14.3 0.0 9 6.6 0.0 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Zn_clus PF00172.18 CAR26760.1 - 7.6e-10 38.8 10.2 1.2e-09 38.1 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DLH PF01738.18 CAR26761.1 - 7.4e-33 113.9 0.0 8.6e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CAR26761.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold EF_assoc_1 PF08355.12 CAR26762.1 - 7.4e-27 92.8 0.5 1.7e-26 91.6 0.5 1.7 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 CAR26762.1 - 3.5e-26 91.0 0.0 1e-25 89.5 0.0 1.8 2 0 0 2 2 1 1 EF hand associated Ras PF00071.22 CAR26762.1 - 5.7e-25 87.8 0.0 6.9e-12 45.3 0.0 2.8 2 1 0 2 2 2 2 Ras family Roc PF08477.13 CAR26762.1 - 9.1e-18 64.6 0.0 2.9e-07 30.7 0.0 3.3 3 0 0 3 3 3 3 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR26762.1 - 6.6e-08 32.2 0.0 3.8e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR26762.1 - 4.8e-07 29.8 0.0 0.0063 16.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 CAR26762.1 - 5.1e-06 25.7 3.2 0.052 13.1 0.9 3.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CAR26762.1 - 0.00023 21.5 1.6 0.084 13.3 0.4 3.3 2 1 1 3 3 3 2 EF-hand domain pair Dynamin_N PF00350.23 CAR26762.1 - 0.00024 21.2 0.3 0.0077 16.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 CAR26762.1 - 0.0028 17.9 0.0 3.4 7.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAR26762.1 - 0.0028 18.1 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain EF-hand_8 PF13833.6 CAR26762.1 - 0.0034 17.2 1.5 0.28 11.1 1.2 2.7 2 0 0 2 2 2 1 EF-hand domain pair AAA_18 PF13238.6 CAR26762.1 - 0.0066 17.0 1.3 0.99 10.0 0.0 4.0 3 2 1 4 4 4 1 AAA domain FeoB_N PF02421.18 CAR26762.1 - 0.0071 15.9 0.0 5.1 6.6 0.0 3.3 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAR26762.1 - 0.0089 16.0 1.1 0.5 10.2 0.1 3.5 4 0 0 4 4 4 1 RsgA GTPase EF-hand_6 PF13405.6 CAR26762.1 - 0.01 15.7 5.1 1.9 8.7 1.2 3.0 2 0 0 2 2 2 0 EF-hand domain GTP_EFTU PF00009.27 CAR26762.1 - 0.011 15.2 0.0 7.1 6.1 0.0 3.4 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain Septin PF00735.18 CAR26762.1 - 0.02 14.2 0.0 0.89 8.8 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 CAR26762.1 - 0.021 14.6 0.0 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain EF-hand_5 PF13202.6 CAR26762.1 - 0.047 13.2 4.6 0.14 11.7 1.2 3.0 2 0 0 2 2 2 0 EF hand AAA_29 PF13555.6 CAR26762.1 - 0.055 13.2 0.0 8 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ShlB PF03865.13 CAR26762.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Proteasome PF00227.26 CAR26763.1 - 2.1e-52 177.4 0.0 2.8e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR26763.1 - 1.6e-11 43.6 0.0 1.6e-11 43.6 0.0 2.2 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature Mto2_bdg PF12808.7 CAR26764.1 - 3e-06 27.4 6.2 3e-06 27.4 6.2 4.6 3 1 1 4 4 4 1 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3450 PF11932.8 CAR26764.1 - 0.00079 18.8 13.4 0.00079 18.8 13.4 5.6 3 1 4 7 7 7 3 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 CAR26764.1 - 0.0062 16.6 21.9 0.0062 16.6 21.9 5.9 5 1 1 6 6 6 2 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.15 CAR26764.1 - 0.011 15.9 3.3 0.011 15.9 3.3 6.1 4 1 1 5 5 5 0 Basic region leucine zipper PikAIV_N PF18605.1 CAR26764.1 - 1.4 8.5 8.4 0.24 11.0 2.5 2.8 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TSC22 PF01166.18 CAR26764.1 - 9.1 6.7 31.6 32 4.9 3.7 7.5 6 1 1 7 7 7 0 TSC-22/dip/bun family eIF2A PF08662.11 CAR26765.1 - 3.4e-24 85.8 3.2 4.4e-21 75.7 0.6 4.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CAR26765.1 - 4.6e-08 32.8 0.1 1.1e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CAR26765.1 - 0.13 13.2 0.6 4e+02 2.1 0.0 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat BolA PF01722.18 CAR26766.1 - 2.5e-13 50.1 0.0 8.8e-13 48.3 0.0 1.8 1 1 0 1 1 1 1 BolA-like protein BolA PF01722.18 CAR26767.1 - 4.7e-26 90.9 0.1 6e-26 90.5 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein GCV_H PF01597.19 CAR26768.1 - 2.3e-42 143.7 0.2 2.7e-42 143.5 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein GP70 PF17429.2 CAR26768.1 - 0.17 11.8 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Gene product 70 MBF1 PF08523.10 CAR26769.1 - 1.9e-23 82.7 1.2 1.9e-23 82.7 1.2 2.0 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CAR26769.1 - 1.8e-13 50.3 0.3 3.1e-13 49.6 0.3 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CAR26769.1 - 5.7e-05 23.4 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CAR26769.1 - 0.005 16.8 0.3 0.0083 16.1 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain TRAP-gamma PF07074.12 CAR26769.1 - 0.28 10.7 0.8 0.37 10.3 0.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) LRR_6 PF13516.6 CAR26770.1 - 1.6e-09 37.1 14.8 0.63 10.2 0.0 7.0 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.7 CAR26770.1 - 1.8e-07 31.3 24.4 0.27 11.7 2.8 6.6 4 3 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CAR26770.1 - 2e-06 27.6 6.9 40 5.3 0.1 6.8 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 CAR26770.1 - 0.00059 19.5 17.4 2.8 7.8 1.9 5.7 4 2 0 4 4 4 3 Leucine rich repeat RasGAP PF00616.19 CAR26770.1 - 0.18 11.5 2.1 3.7 7.2 1.1 2.3 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Acyltransf_C PF16076.5 CAR26771.1 - 6.4e-05 23.0 0.3 0.0002 21.4 0.1 1.9 2 0 0 2 2 2 1 Acyltransferase C-terminus OHA PF14418.6 CAR26771.1 - 0.0016 18.2 0.2 1.3 8.8 0.0 2.7 2 0 0 2 2 2 2 OST-HTH Associated domain CybS PF05328.12 CAR26772.1 - 1.1e-53 180.4 0.0 1.3e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Cauli_VI PF01693.16 CAR26773.1 - 8.3e-31 106.0 7.5 5.1e-19 68.3 1.5 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 CAR26773.1 - 2.4e-30 105.6 0.1 4.6e-30 104.7 0.1 1.5 1 0 0 1 1 1 1 RNase H DUF4928 PF16280.5 CAR26773.1 - 0.074 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) Bul1_N PF04425.12 CAR26774.1 - 2.2e-47 161.9 1.9 8.9e-30 103.8 0.2 2.4 3 0 0 3 3 3 2 Bul1 N terminus Bul1_C PF04426.12 CAR26774.1 - 3e-32 112.1 2.5 2.7e-16 59.8 0.5 2.4 1 1 1 2 2 2 2 Bul1 C terminus Proteasome PF00227.26 CAR26775.1 - 1.3e-46 158.5 0.0 1.5e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR26775.1 - 6.7e-12 44.8 0.1 1.3e-11 43.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PikAIV_N PF18605.1 CAR26775.1 - 0.093 12.3 0.1 0.22 11.1 0.1 1.6 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF3336 PF11815.8 CAR26776.1 - 1.8e-26 92.5 0.1 3.4e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CAR26776.1 - 1.2e-07 32.1 0.0 2.3e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Tautomerase PF01361.21 CAR26777.1 - 0.0051 16.7 0.0 0.01 15.7 0.0 1.6 1 0 0 1 1 1 1 Tautomerase enzyme ELP6 PF09807.9 CAR26777.1 - 0.033 13.6 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Elongation complex protein 6 RAC_head PF16717.5 CAR26778.1 - 5.3e-20 72.2 6.1 5.3e-20 72.2 6.1 3.2 4 1 0 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 CAR26778.1 - 6.1e-15 55.1 0.5 6.1e-15 55.1 0.5 2.0 2 0 0 2 2 2 1 DnaJ domain SURF4 PF02077.15 CAR26779.1 - 3.9e-102 341.4 10.6 4.5e-102 341.2 10.6 1.0 1 0 0 1 1 1 1 SURF4 family MerC PF03203.14 CAR26779.1 - 2.5 8.6 10.9 2.7 8.5 2.0 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein IPP-2 PF04979.14 CAR26780.1 - 4.2e-24 85.8 17.1 9.8e-24 84.6 15.0 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Peptidase_C37 PF05416.12 CAR26780.1 - 0.49 8.9 5.9 0.57 8.6 5.9 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Methyltrn_RNA_3 PF02598.17 CAR26781.1 - 2.9e-74 250.2 0.0 3.6e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase MurJ PF03023.14 CAR26781.1 - 0.14 10.8 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Lipid II flippase MurJ Glyco_hydro_17 PF00332.18 CAR26782.1 - 1.7e-84 284.1 3.4 1.9e-84 283.9 3.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 eIF-3c_N PF05470.12 CAR26783.1 - 6.5e-163 543.2 12.8 4.4e-125 418.3 1.6 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CAR26783.1 - 7.8e-13 48.9 0.3 6.4e-12 45.9 0.3 2.7 1 1 0 1 1 1 1 PCI domain DUF1548 PF07579.11 CAR26783.1 - 1.6 9.0 5.7 3 8.2 0.2 3.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) Importin_rep_6 PF18829.1 CAR26784.1 - 1.8e-47 159.9 7.4 2.5e-47 159.5 0.2 3.9 4 0 0 4 4 4 1 Importin repeat 6 Importin_rep_4 PF18808.1 CAR26784.1 - 4.6e-31 107.0 0.5 4.6e-31 107.0 0.5 3.5 4 0 0 4 4 3 1 Importin repeat Importin_rep_5 PF18816.1 CAR26784.1 - 4.7e-24 84.4 2.3 4.2e-23 81.4 0.2 3.1 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 CAR26784.1 - 2e-23 82.5 0.8 7.4e-11 42.3 0.0 7.2 6 2 2 8 8 6 3 HEAT-like repeat HEAT_2 PF13646.6 CAR26784.1 - 3.7e-14 52.9 0.2 5.4e-05 23.5 0.0 6.1 4 2 3 7 7 7 4 HEAT repeats HEAT PF02985.22 CAR26784.1 - 7.8e-13 47.5 1.6 0.036 14.3 0.0 9.2 9 0 0 9 9 9 1 HEAT repeat RIX1 PF08167.12 CAR26784.1 - 3.5e-07 30.2 0.1 0.00084 19.1 0.1 4.4 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 CAR26784.1 - 8.3e-06 25.2 10.7 0.0018 17.5 3.0 3.7 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 CAR26784.1 - 1.1e-05 25.9 0.1 0.077 13.6 0.0 5.0 2 1 2 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CAR26784.1 - 0.00015 21.9 1.1 2.5 8.1 0.0 5.1 3 3 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CAR26784.1 - 0.00028 20.6 0.3 0.2 11.2 0.3 3.7 3 0 0 3 3 3 1 CLASP N terminal Arm PF00514.23 CAR26784.1 - 0.001 19.1 3.3 30 4.8 0.0 5.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 CAR26784.1 - 0.0011 18.9 4.8 0.22 11.4 0.3 5.1 5 2 2 7 7 7 1 Domain of unknown function (DUF3385) IFRD PF05004.13 CAR26784.1 - 0.02 14.0 0.3 0.02 14.0 0.3 3.4 4 1 2 6 6 6 0 Interferon-related developmental regulator (IFRD) DnaJ-X PF14308.6 CAR26784.1 - 0.12 11.9 0.0 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 X-domain of DnaJ-containing RTP1_C1 PF10363.9 CAR26784.1 - 0.14 12.4 0.8 19 5.5 0.1 4.3 5 0 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 PBP1_TM PF14812.6 CAR26784.1 - 3 8.3 12.5 0.23 11.9 1.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.16 CAR26785.1 - 6.4e-50 170.0 38.8 1e-49 169.4 38.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR26785.1 - 7.7e-15 54.3 8.9 1.1e-14 53.9 8.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CAR26785.1 - 2.3e-14 53.2 11.6 2.3e-14 53.2 11.6 2.8 4 0 0 4 4 4 1 Sugar (and other) transporter MFS_1_like PF12832.7 CAR26785.1 - 3.5e-05 22.8 4.9 3.5e-05 22.8 4.9 2.4 1 1 1 2 2 2 1 MFS_1 like family GNVR PF13807.6 CAR26785.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.8 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase NDUF_B12 PF08122.12 CAR26785.1 - 0.19 11.8 1.2 0.29 11.2 0.0 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Sulfate_transp PF00916.20 CAR26786.1 - 3.3e-117 391.5 9.8 4.2e-117 391.1 9.8 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CAR26786.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 STAS domain Consortin_C PF15281.6 CAR26786.1 - 0.16 11.9 1.6 0.84 9.6 1.6 2.3 1 0 0 1 1 1 0 Consortin C-terminus DUF3611 PF12263.8 CAR26786.1 - 0.32 10.9 2.4 0.72 9.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3611) MFS_MOT1 PF16983.5 CAR26786.1 - 3.7 8.0 8.2 0.11 12.9 0.8 2.3 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily ANAPC4 PF12896.7 CAR26787.1 - 2.7e-25 89.1 1.5 5e-25 88.2 0.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 CAR26787.1 - 0.013 15.8 0.0 0.066 13.5 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain SUI1 PF01253.22 CAR26788.1 - 1.6e-15 57.4 0.0 3.8e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CAR26788.1 - 3e-08 34.3 0.1 1e-07 32.5 0.1 2.0 1 1 0 1 1 1 1 Pre-PUA-like domain SWIB PF02201.18 CAR26788.1 - 8.1e-06 25.6 0.3 2.4e-05 24.1 0.3 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Ribosomal_L1 PF00687.21 CAR26789.1 - 8.1e-25 87.7 0.1 9.9e-25 87.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Rab_bind PF16704.5 CAR26789.1 - 0.042 13.9 1.0 0.076 13.1 1.0 1.3 1 0 0 1 1 1 0 Rab binding domain Orthopox_A5L PF06193.11 CAR26789.1 - 0.25 10.7 3.1 0.75 9.2 0.2 2.1 1 1 1 2 2 2 0 Orthopoxvirus A5L protein-like Ribosomal_L34 PF00468.17 CAR26790.1 - 2.9e-18 65.5 7.4 2.9e-18 65.5 7.4 1.5 1 1 0 1 1 1 1 Ribosomal protein L34 GEP5 PF17053.5 CAR26791.1 - 1.8e-77 260.2 5.8 2.2e-77 259.9 5.8 1.0 1 0 0 1 1 1 1 Genetic interactor of prohibitin 5 Rep_fac-A_3 PF08661.11 CAR26791.1 - 0.098 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Replication factor A protein 3 Securin PF04856.13 CAR26792.1 - 4e-24 85.9 10.8 6.7e-24 85.1 10.8 1.3 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor Nucleo_P87 PF07267.11 CAR26792.1 - 0.1 11.5 2.4 0.19 10.5 2.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DnaJ_C PF01556.18 CAR26793.1 - 1.2e-33 116.2 0.0 1.8e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAR26793.1 - 2.1e-25 88.6 1.3 3.4e-25 87.9 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAR26793.1 - 9e-12 45.2 16.1 2.7e-11 43.7 16.3 1.7 1 1 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.6 CAR26793.1 - 0.0015 18.9 4.7 0.0077 16.7 0.6 2.5 2 0 0 2 2 2 1 Cytochrome c3 Anti-TRAP PF15777.5 CAR26793.1 - 0.0084 16.0 13.9 0.04 13.9 2.2 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_C7 PF14522.6 CAR26793.1 - 2 8.5 12.9 14 5.8 12.1 2.3 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Aminotran_1_2 PF00155.21 CAR26794.1 - 1.1e-36 126.8 0.0 1.6e-36 126.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CAR26794.1 - 0.043 13.1 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CAR26794.1 - 0.064 11.8 0.0 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Gaa1 PF04114.14 CAR26796.1 - 1.2e-118 397.3 12.9 1.6e-118 396.9 12.9 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PHO4 PF01384.20 CAR26796.1 - 1.7 7.6 8.6 1.9 7.4 7.4 1.6 2 0 0 2 2 2 0 Phosphate transporter family SMC_N PF02463.19 CAR26798.1 - 4.5e-61 206.1 64.7 3.6e-60 203.1 64.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CAR26798.1 - 2.5e-23 82.6 0.0 8.7e-23 80.9 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CAR26798.1 - 7.1e-11 42.5 17.8 2.1e-05 24.5 3.9 4.1 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CAR26798.1 - 4.3e-06 26.7 15.1 4.3e-06 26.7 15.1 4.5 2 2 2 4 4 4 1 AAA ATPase domain Sec34 PF04136.15 CAR26798.1 - 2.9e-05 24.0 5.9 2.9e-05 24.0 5.9 7.6 4 2 3 7 7 7 2 Sec34-like family AAA_29 PF13555.6 CAR26798.1 - 0.00099 18.8 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RasGAP_C PF03836.15 CAR26798.1 - 0.0057 16.8 3.5 0.0057 16.8 3.5 8.3 2 2 5 7 7 7 1 RasGAP C-terminus TolA_bind_tri PF16331.5 CAR26798.1 - 0.029 14.5 0.7 0.029 14.5 0.7 8.4 8 1 1 9 9 9 0 TolA binding protein trimerisation ABC_tran PF00005.27 CAR26798.1 - 1.5 9.3 0.0 1.5 9.3 0.0 6.3 3 2 0 4 4 4 0 ABC transporter Actin PF00022.19 CAR26799.1 - 5.9e-51 173.3 0.0 6.5e-50 169.9 0.0 1.9 1 1 0 1 1 1 1 Actin Ses_B PF17046.5 CAR26799.1 - 0.056 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein PEX-2N PF09263.10 CAR26799.1 - 0.061 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal FGGY_C PF02782.16 CAR26800.1 - 4.2e-51 173.5 0.1 8.1e-51 172.6 0.1 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CAR26800.1 - 5.5e-22 78.5 0.0 9.7e-21 74.4 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 CAR26800.1 - 0.046 13.6 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Hexokinase Rax2 PF12768.7 CAR26801.1 - 3e-33 115.1 0.6 3e-33 115.1 0.6 5.1 5 1 1 6 6 6 2 Cortical protein marker for cell polarity SR-25 PF10500.9 CAR26801.1 - 7 6.2 7.9 19 4.8 7.9 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TRAPPC-Trs85 PF12739.7 CAR26802.1 - 2.2e-108 362.9 1.3 2.2e-108 362.9 1.3 2.0 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Vac14_Fig4_bd PF11916.8 CAR26802.1 - 0.049 13.3 2.8 4.3 7.0 0.2 3.0 3 0 0 3 3 3 0 Vacuolar protein 14 C-terminal Fig4p binding EMP70 PF02990.16 CAR26803.1 - 2e-193 643.8 13.1 2.8e-193 643.3 13.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF2205 PF10224.9 CAR26804.1 - 1.3e-07 31.5 1.8 1.3e-07 31.5 1.8 1.6 2 0 0 2 2 2 1 Short coiled-coil protein DUF5094 PF17015.5 CAR26804.1 - 0.0052 16.9 1.4 0.0065 16.6 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5094) RBD-FIP PF09457.10 CAR26804.1 - 0.021 14.7 0.3 0.051 13.5 0.3 1.6 1 0 0 1 1 1 0 FIP domain Serinc PF03348.15 CAR26806.1 - 7.9e-134 446.8 11.4 9.2e-134 446.6 11.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) YtpI PF14007.6 CAR26806.1 - 0.034 14.3 0.9 0.034 14.3 0.9 2.7 3 0 0 3 3 3 0 YtpI-like protein Rad51 PF08423.11 CAR26807.1 - 4.6e-113 376.7 0.3 6.2e-113 376.3 0.1 1.3 2 0 0 2 2 2 1 Rad51 RecA PF00154.21 CAR26807.1 - 4.2e-11 42.8 0.1 5.8e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CAR26807.1 - 9.1e-07 28.5 1.9 2.2e-06 27.2 0.4 2.4 2 1 0 2 2 2 1 KaiC HHH_5 PF14520.6 CAR26807.1 - 1.7e-05 25.4 0.4 5.1e-05 23.8 0.2 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain PAXNEB PF05625.11 CAR26807.1 - 0.092 11.9 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 PAXNEB protein PH_4 PF15404.6 CAR26808.1 - 2e-77 259.1 0.1 5.5e-77 257.7 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.6 CAR26808.1 - 4.1e-25 87.2 0.0 1.3e-24 85.5 0.0 2.0 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 CAR26808.1 - 1.1e-05 25.9 3.7 0.33 11.5 0.1 5.0 4 1 0 4 4 4 2 PH domain PH_12 PF16457.5 CAR26808.1 - 0.0028 18.2 0.2 0.016 15.7 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 CAR26808.1 - 0.1 12.4 3.0 0.45 10.3 2.1 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Ste5_C PF12194.8 CAR26809.1 - 2.1e-81 272.4 0.0 3.6e-81 271.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase Fus3-binding zf-RING_2 PF13639.6 CAR26809.1 - 0.0021 18.3 2.8 0.0045 17.3 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 CAR26809.1 - 0.021 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CAR26809.1 - 0.021 14.6 1.3 0.051 13.3 1.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 CAR26809.1 - 0.049 13.7 0.4 0.12 12.4 0.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CAR26809.1 - 0.11 12.5 2.5 0.38 10.8 2.5 1.9 1 1 0 1 1 1 0 zinc-RING finger domain E1_dh PF00676.20 CAR26810.1 - 3.3e-118 394.0 0.1 4e-118 393.7 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CAR26810.1 - 0.0034 16.6 0.1 0.006 15.8 0.1 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Cyclin_N PF00134.23 CAR26811.1 - 1e-21 77.0 0.0 1.8e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CAR26811.1 - 1.5e-07 31.9 0.0 1.5e-07 31.9 0.0 1.8 2 1 0 2 2 2 1 Cyclin DNA_pol3_delta2 PF13177.6 CAR26812.1 - 1e-17 64.4 0.1 4.6e-12 46.0 0.1 3.0 2 1 1 3 3 3 2 DNA polymerase III, delta subunit AAA PF00004.29 CAR26812.1 - 3.1e-17 63.2 0.0 5.8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CAR26812.1 - 6.1e-14 52.2 0.2 3.6e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 CAR26812.1 - 3.5e-08 33.6 0.0 2.9e-07 30.6 0.0 2.4 2 1 0 2 2 2 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 CAR26812.1 - 9.2e-07 28.8 0.2 1.9e-06 27.8 0.1 1.6 2 0 0 2 2 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 CAR26812.1 - 3e-06 27.7 0.0 8e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CAR26812.1 - 8.9e-06 25.5 0.0 1.5e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CAR26812.1 - 2e-05 24.9 0.4 0.13 12.5 0.1 2.7 1 1 1 2 2 2 2 AAA domain AAA_assoc_2 PF16193.5 CAR26812.1 - 5e-05 23.5 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain DUF815 PF05673.13 CAR26812.1 - 5.6e-05 22.4 0.0 0.00022 20.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 CAR26812.1 - 7.1e-05 22.8 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR26812.1 - 0.00013 21.7 0.0 0.0014 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CAR26812.1 - 0.00031 20.6 0.1 0.00099 19.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 CAR26812.1 - 0.00034 20.7 0.0 0.024 14.6 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR26812.1 - 0.00079 19.2 0.1 0.017 14.9 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase IstB_IS21 PF01695.17 CAR26812.1 - 0.0011 18.8 0.1 0.005 16.6 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 CAR26812.1 - 0.0014 18.1 0.0 0.0045 16.5 0.0 1.7 1 1 1 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 CAR26812.1 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAR26812.1 - 0.0034 17.4 0.0 0.015 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 CAR26812.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 CAR26812.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CAR26812.1 - 0.026 13.9 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CAR26812.1 - 0.028 14.0 0.4 0.52 9.9 0.0 2.4 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.22 CAR26812.1 - 0.035 14.5 0.1 0.097 13.1 0.0 1.9 2 1 0 2 2 1 0 RNA helicase AAA_19 PF13245.6 CAR26812.1 - 0.047 14.0 0.2 2.6 8.4 0.0 2.6 2 1 0 3 3 2 0 AAA domain Methyltransf_31 PF13847.6 CAR26812.1 - 0.05 13.4 0.1 0.1 12.4 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain AAA_18 PF13238.6 CAR26812.1 - 0.051 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CAR26812.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 CAR26812.1 - 0.067 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 CAR26812.1 - 0.068 13.4 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.23 CAR26812.1 - 0.088 11.5 0.0 0.19 10.4 0.0 1.5 2 0 0 2 2 2 0 SNF2 family N-terminal domain Mid1 PF12929.7 CAR26813.1 - 1.6e-126 423.0 11.1 1.8e-126 422.8 11.1 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 CAR26813.1 - 0.00027 21.5 6.8 0.0079 16.8 6.8 2.6 1 1 0 1 1 1 1 Fz domain TruB_N PF01509.18 CAR26814.1 - 4e-41 140.8 5.2 1.5e-39 135.7 0.1 3.1 3 0 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CAR26814.1 - 0.00044 20.3 0.0 0.0034 17.5 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain ORC_WH_C PF18137.1 CAR26814.1 - 8.1 6.5 9.6 1.2 9.2 4.7 2.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Erf4 PF10256.9 CAR26815.1 - 1.2e-32 112.4 0.0 1.6e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Get5_bdg PF16843.5 CAR26816.1 - 1.7e-28 97.8 2.1 2.1e-28 97.6 1.1 1.6 2 0 0 2 2 2 1 Binding domain to Get4 on Get5, Golgi to ER traffic protein Get5_C PF18514.1 CAR26816.1 - 3.7e-11 42.5 0.6 7.7e-11 41.5 0.6 1.6 1 0 0 1 1 1 1 Get5 C-terminal domain ubiquitin PF00240.23 CAR26816.1 - 5.2e-10 38.9 0.1 9.2e-10 38.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CAR26816.1 - 9.2e-05 22.2 0.1 0.00019 21.2 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 CAR26816.1 - 0.00024 21.2 0.1 0.00063 19.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RabGAP-TBC PF00566.18 CAR26817.1 - 5.1e-44 150.5 4.2 6.2e-43 147.0 4.2 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PalH PF08733.10 CAR26818.1 - 2.1e-85 286.7 7.7 2.5e-85 286.4 7.7 1.1 1 0 0 1 1 1 1 PalH/RIM21 Pet20 PF08692.10 CAR26819.1 - 4.8e-32 111.4 1.0 1.2e-31 110.1 0.2 2.1 2 0 0 2 2 2 1 Mitochondrial protein Pet20 DCB PF16213.5 CAR26820.1 - 6e-46 156.3 1.9 6e-46 156.3 1.9 3.7 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CAR26820.1 - 3e-34 118.2 3.6 3e-34 118.2 3.6 5.0 6 0 0 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 CAR26820.1 - 3.6e-12 45.3 0.3 5.2e-10 38.1 0.1 2.4 2 0 0 2 2 2 2 C-terminal region of Mon2 protein Pkinase PF00069.25 CAR26821.1 - 9.9e-65 218.5 0.7 7e-64 215.7 0.7 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR26821.1 - 1.7e-50 171.7 0.0 2.9e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CAR26821.1 - 2.4e-23 82.2 0.2 7.3e-23 80.7 0.2 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 CAR26821.1 - 4.6e-12 46.4 0.0 1.1e-11 45.2 0.0 1.7 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 CAR26821.1 - 7.6e-07 28.2 1.1 3.8e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CAR26821.1 - 7.1e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR26821.1 - 0.099 12.6 0.1 0.26 11.2 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family RF-1 PF00472.20 CAR26822.1 - 1.9e-18 66.5 0.3 2.8e-18 66.0 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain Gag_p10 PF02337.17 CAR26822.1 - 0.1 12.5 0.3 0.24 11.4 0.1 1.7 2 0 0 2 2 2 0 Retroviral GAG p10 protein NTP_transf_2 PF01909.23 CAR26823.1 - 8.6e-19 67.6 0.0 3.1e-18 65.9 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CAR26823.1 - 5.9e-13 48.8 0.0 1.4e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 CAR26823.1 - 0.0032 17.5 0.0 0.0088 16.1 0.0 1.7 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DNA_pol_B_palm PF14792.6 CAR26823.1 - 0.045 14.0 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm ADK PF00406.22 CAR26824.1 - 9.5e-60 201.1 0.0 1.1e-59 200.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAR26824.1 - 1e-24 87.5 0.1 1.7e-24 86.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CAR26824.1 - 1.6e-17 63.1 0.0 4.4e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CAR26824.1 - 9e-07 29.2 0.0 1.8e-06 28.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR26824.1 - 2.2e-06 28.3 0.0 5.1e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 CAR26824.1 - 0.0069 16.7 0.1 0.96 9.7 0.0 2.3 1 1 1 2 2 2 1 Hydin Adenylate kinase-like domain Thymidylate_kin PF02223.17 CAR26824.1 - 0.017 14.8 0.1 0.05 13.3 0.0 1.7 1 1 1 2 2 2 0 Thymidylate kinase Cytidylate_kin PF02224.18 CAR26824.1 - 0.037 13.8 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase GCR1_C PF12550.8 CAR26825.1 - 4.5e-23 81.4 0.4 7.9e-23 80.6 0.4 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TFIIA PF03153.13 CAR26825.1 - 0.0017 18.4 17.6 0.002 18.2 17.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SIKE PF05769.11 CAR26825.1 - 0.02 14.8 0.5 0.02 14.8 0.5 2.0 2 0 0 2 2 2 0 SIKE family Tropomyosin PF00261.20 CAR26825.1 - 0.022 14.2 0.5 0.022 14.2 0.5 1.4 2 0 0 2 2 2 0 Tropomyosin DUF4551 PF15087.6 CAR26825.1 - 0.59 8.9 10.0 0.89 8.3 10.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 CAR26825.1 - 0.7 8.5 8.1 0.84 8.3 8.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 CAR26825.1 - 6.9 4.8 16.3 8.9 4.4 16.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YlbD_coat PF14071.6 CAR26827.1 - 0.036 14.3 0.2 0.1 12.9 0.1 1.9 1 1 0 1 1 1 0 Putative coat protein Redoxin PF08534.10 CAR26828.1 - 2.7e-29 101.8 0.0 3.4e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin MFS_1 PF07690.16 CAR26829.1 - 2.6e-29 102.3 36.2 2.6e-29 102.3 36.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CAR26830.1 - 2.5e-28 99.0 36.7 2.5e-28 99.0 36.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L18 PF17135.4 CAR26831.1 - 8.6e-84 279.6 2.9 9.5e-84 279.4 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CAR26831.1 - 0.014 16.0 0.9 0.014 16.0 0.9 2.0 2 1 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Nudc_N PF14050.6 CAR26831.1 - 0.11 12.4 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. Ribosomal_S19e PF01090.19 CAR26832.1 - 1.9e-54 183.1 0.1 2.1e-54 182.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Nramp PF01566.18 CAR26833.1 - 7.5e-86 288.3 17.9 1.1e-84 284.5 17.9 2.1 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein RRM_1 PF00076.22 CAR26834.1 - 3.1e-34 116.6 0.5 1.1e-17 63.6 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR26834.1 - 7.4e-12 45.2 0.4 3.7e-06 27.0 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif Glyco_H_20C_C PF18088.1 CAR26834.1 - 0.0022 17.9 0.7 0.0057 16.5 0.7 1.6 1 0 0 1 1 1 1 Glycoside Hydrolase 20C C-terminal domain OB_RNB PF08206.11 CAR26834.1 - 0.023 14.3 0.1 11 5.8 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain MID_MedPIWI PF18296.1 CAR26834.1 - 1.2 8.8 21.3 0.49 10.1 0.1 2.2 2 0 0 2 2 2 0 MID domain of medPIWI SMYLE_N PF18615.1 CAR26834.1 - 2.1 7.8 8.2 4.2 6.8 8.2 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain UPF0020 PF01170.18 CAR26835.1 - 3.9e-12 46.3 0.0 2.7e-10 40.3 0.0 2.5 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CAR26835.1 - 0.0012 18.6 0.1 0.042 13.6 0.0 2.4 2 1 0 2 2 2 1 DNA methylase MethyltransfD12 PF02086.15 CAR26835.1 - 0.0099 15.6 1.0 4.8 6.8 0.0 2.6 2 1 1 3 3 3 2 D12 class N6 adenine-specific DNA methyltransferase DUF2489 PF10675.9 CAR26835.1 - 0.22 11.4 0.1 0.36 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Ras PF00071.22 CAR26836.1 - 7e-27 94.0 0.1 3.9e-22 78.6 0.1 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CAR26836.1 - 1.2e-16 61.0 0.1 7.3e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 CAR26836.1 - 5.3e-06 25.8 0.1 0.016 14.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Arf PF00025.21 CAR26836.1 - 2.7e-05 23.7 0.6 0.00017 21.1 0.2 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_7 PF12775.7 CAR26836.1 - 0.00011 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 CAR26836.1 - 0.0017 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 CAR26836.1 - 0.068 12.6 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein TIP49 PF06068.13 CAR26836.1 - 0.077 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA PF00004.29 CAR26836.1 - 0.084 13.3 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAR26836.1 - 0.093 13.1 0.0 0.16 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AFG1_ATPase PF03969.16 CAR26836.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase TRM13 PF05206.14 CAR26837.1 - 2.4e-85 286.2 0.5 4.2e-85 285.4 0.5 1.4 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 CAR26837.1 - 1.3e-10 40.9 0.8 1.3e-10 40.9 0.8 2.4 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.8 CAR26837.1 - 4.3e-10 39.2 2.2 1e-09 37.9 2.2 1.7 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein Ldh_1_N PF00056.23 CAR26838.1 - 6.3e-41 139.8 0.2 9.6e-41 139.2 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CAR26838.1 - 1.6e-34 119.3 0.0 2.3e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Bax1-I PF01027.20 CAR26839.1 - 5.4e-44 150.5 22.6 6.6e-44 150.2 22.6 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2157 PF09925.9 CAR26839.1 - 0.018 14.8 6.9 0.018 14.8 6.9 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Lig_chan PF00060.26 CAR26839.1 - 0.055 13.3 2.8 0.13 12.0 2.8 1.6 1 1 0 1 1 1 0 Ligand-gated ion channel BaxI_1 PF12811.7 CAR26839.1 - 0.091 12.3 20.5 0.37 10.3 20.4 1.8 1 1 0 1 1 1 0 Bax inhibitor 1 like Ribosomal_L23eN PF03939.13 CAR26840.1 - 1.1e-19 70.4 9.7 1.1e-19 70.4 9.7 2.0 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CAR26840.1 - 8.4e-16 58.1 2.8 8.4e-16 58.1 2.8 2.5 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_S11 PF00411.19 CAR26841.1 - 0.00035 20.9 0.0 0.00057 20.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Pkinase PF00069.25 CAR26842.1 - 1.3e-56 191.9 0.0 1.5e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR26842.1 - 3.1e-28 98.8 0.0 4.1e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR26842.1 - 8.4e-05 22.0 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR26842.1 - 0.00031 20.8 0.1 0.0011 18.9 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CAR26842.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UPF0220 PF05255.11 CAR26843.1 - 5.7e-70 234.2 3.5 7.2e-70 233.8 3.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) V_ATPase_I_N PF18670.1 CAR26843.1 - 0.059 13.8 0.0 5.4 7.5 0.0 2.3 2 0 0 2 2 2 0 V-type ATPase subunit I, N-terminal domain Kri1_C PF12936.7 CAR26844.1 - 2.9e-30 104.3 3.0 2.9e-30 104.3 3.0 3.9 2 1 1 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.12 CAR26844.1 - 1.4e-14 54.5 11.8 1.4e-14 54.5 11.8 5.5 5 3 0 5 5 5 1 KRI1-like family CorA PF01544.18 CAR26845.1 - 2.1e-38 132.3 0.9 6e-37 127.5 0.9 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CAP_N PF01213.19 CAR26846.1 - 0.55 9.7 3.4 0.92 8.9 3.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-DNL PF05180.12 CAR26847.1 - 1e-30 105.4 1.8 1.7e-30 104.7 1.8 1.4 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 CAR26847.1 - 0.0081 16.1 0.9 0.32 11.0 0.0 2.3 2 0 0 2 2 2 1 zinc-ribbon domain CGGC PF08821.11 CAR26847.1 - 0.02 15.1 0.2 0.028 14.6 0.2 1.2 1 0 0 1 1 1 0 CGGC domain Elf1 PF05129.13 CAR26847.1 - 0.028 14.5 0.5 0.042 13.9 0.5 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like TFIIS_C PF01096.18 CAR26847.1 - 0.034 14.0 0.6 3.2 7.7 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-CSL PF05207.13 CAR26847.1 - 0.042 13.6 0.2 0.079 12.7 0.2 1.4 1 0 0 1 1 1 0 CSL zinc finger HypA PF01155.19 CAR26847.1 - 0.084 12.9 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ZPR1 PF03367.13 CAR26847.1 - 0.16 11.8 2.5 0.45 10.4 2.0 2.0 1 1 1 2 2 2 0 ZPR1 zinc-finger domain Zn_Tnp_IS1595 PF12760.7 CAR26847.1 - 1.4 8.9 4.2 12 6.0 0.3 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain F-box-like PF12937.7 CAR26848.1 - 6.1e-06 26.0 0.5 6.1e-06 26.0 0.5 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CAR26848.1 - 6.8e-05 22.6 0.2 6.8e-05 22.6 0.2 2.6 2 0 0 2 2 2 1 F-box domain Glyco_hydro_72 PF03198.14 CAR26849.1 - 6e-136 452.8 0.9 7.6e-136 452.5 0.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 CAR26849.1 - 0.0014 18.1 0.1 0.0066 15.9 0.2 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) tRNA_anti-codon PF01336.25 CAR26850.1 - 2.4e-09 37.1 0.4 5.9e-09 35.8 0.4 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 CAR26850.1 - 3.3e-06 27.7 0.0 1.9e-05 25.2 0.0 2.1 1 1 1 2 2 2 1 Replication protein A C terminal tRNA_anti_2 PF13742.6 CAR26850.1 - 0.07 13.3 0.4 0.16 12.2 0.4 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RMI2 PF16100.5 CAR26850.1 - 0.19 11.6 1.3 0.57 10.0 1.3 1.9 1 1 0 1 1 1 0 RecQ-mediated genome instability protein 2 TPR_8 PF13181.6 CAR26851.1 - 2.8e-09 36.5 1.6 0.0026 17.9 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAR26851.1 - 1.4e-06 28.0 0.1 0.13 12.5 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAR26851.1 - 1.9e-05 24.3 0.5 0.99 9.3 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAR26851.1 - 2e-05 25.0 3.3 0.0098 16.4 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAR26851.1 - 9.1e-05 23.0 6.5 0.97 10.4 0.1 6.5 6 2 2 8 8 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 CAR26851.1 - 0.0034 16.6 0.9 0.31 10.2 0.4 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAR26851.1 - 0.0039 17.5 3.1 1.9 8.8 0.1 4.3 3 1 0 4 4 4 1 Tetratricopeptide repeat Clathrin PF00637.20 CAR26851.1 - 0.02 14.7 2.8 0.12 12.2 0.1 2.8 3 0 0 3 3 3 0 Region in Clathrin and VPS TPR_17 PF13431.6 CAR26851.1 - 0.08 13.4 0.5 1.3 9.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ChAPs PF09295.10 CAR26851.1 - 0.13 11.2 0.6 0.23 10.4 0.0 1.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 CAR26851.1 - 0.13 12.4 0.8 1.4 9.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR26851.1 - 0.38 11.0 4.2 2.9 8.2 0.1 3.4 3 1 0 3 3 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 CAR26851.1 - 0.6 10.8 2.5 1.2 9.8 0.0 2.8 3 1 1 4 4 2 0 Tetratricopeptide repeat Myb_DNA-bind_5 PF13873.6 CAR26852.1 - 4e-05 23.6 0.6 0.00012 22.1 0.6 1.8 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain SPX PF03105.19 CAR26852.1 - 0.85 9.5 18.2 0.56 10.1 16.8 1.3 1 1 0 1 1 1 0 SPX domain ATP11 PF06644.11 CAR26853.1 - 3e-86 289.6 0.5 3.5e-86 289.4 0.5 1.0 1 0 0 1 1 1 1 ATP11 protein Mt_ATP-synt_D PF05873.12 CAR26853.1 - 0.028 14.3 0.4 0.069 13.0 0.4 1.6 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) PDT PF00800.18 CAR26854.1 - 3.3e-54 183.5 0.0 4.1e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 CAR26854.1 - 0.042 13.6 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 ACT domain zf-rbx1 PF12678.7 CAR26855.1 - 3.7e-23 81.6 13.2 6.3e-23 80.8 13.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAR26855.1 - 5.1e-17 61.7 10.5 6.5e-17 61.4 10.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CAR26855.1 - 8.7e-06 26.0 14.0 0.00042 20.6 14.0 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CAR26855.1 - 0.0023 17.8 12.0 0.023 14.6 12.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAR26855.1 - 0.0037 17.0 1.1 0.0037 17.0 1.1 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CAR26855.1 - 0.0063 16.3 14.0 1.1 9.2 14.0 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CAR26855.1 - 0.26 11.5 0.4 0.26 11.5 0.4 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 CAR26855.1 - 1.1 9.0 14.7 0.12 12.0 5.3 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 CAR26855.1 - 1.1 9.3 8.7 3.5 7.7 8.7 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CAR26855.1 - 1.1 9.2 10.6 2.8 7.9 4.4 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR26855.1 - 2.2 8.3 9.5 10 6.2 9.5 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.11 CAR26855.1 - 4.8 7.6 11.3 36 4.8 11.3 2.2 1 1 0 1 1 1 0 RING-like domain Med7 PF05983.11 CAR26856.1 - 3.4e-65 219.7 5.8 3.9e-65 219.5 5.8 1.0 1 0 0 1 1 1 1 MED7 protein 6PF2K PF01591.18 CAR26857.1 - 2.3e-49 167.7 0.5 4.6e-49 166.7 0.5 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 CAR26857.1 - 0.0005 20.3 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF5409 PF17421.2 CAR26857.1 - 0.0062 17.2 0.1 0.016 15.9 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5409) DUF3718 PF12514.8 CAR26857.1 - 0.062 13.5 0.4 0.23 11.6 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) KTI12 PF08433.10 CAR26857.1 - 0.072 12.5 0.1 0.21 11.0 0.0 1.8 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_18 PF13238.6 CAR26857.1 - 0.096 13.2 0.2 0.4 11.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.11 CAR26857.1 - 0.13 12.4 0.9 0.6 10.2 0.3 2.1 2 0 0 2 2 2 0 tRNA ligase kinase domain DUF3399 PF11879.8 CAR26857.1 - 0.39 11.1 3.5 0.27 11.6 1.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3399) WD40 PF00400.32 CAR26858.1 - 1.1e-32 111.6 12.0 7.5e-06 26.6 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR26858.1 - 3e-18 65.9 0.3 0.012 15.8 0.0 5.7 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR26858.1 - 2.3e-06 27.7 2.1 4.7e-05 23.4 0.9 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR26858.1 - 3.6e-05 22.9 0.9 0.73 8.7 0.0 4.1 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CAR26858.1 - 0.0082 14.8 0.4 0.17 10.5 0.1 2.4 2 1 0 2 2 2 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 CAR26858.1 - 0.058 13.4 0.1 13 5.8 0.0 3.1 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region MFS_1 PF07690.16 CAR26859.1 - 7e-21 74.5 35.1 1.9e-16 59.9 6.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR26860.1 - 5e-119 398.1 34.3 5.8e-119 397.9 34.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR26860.1 - 7.2e-20 71.2 42.2 3.2e-16 59.2 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_ribbon_17 PF17120.5 CAR26861.1 - 5.9e-09 35.4 1.8 1.3e-08 34.3 1.8 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CAR26861.1 - 1.5e-08 35.1 3.9 0.0022 18.8 0.1 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-rbx1 PF12678.7 CAR26861.1 - 0.0044 17.3 3.5 0.0044 17.3 3.5 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CAR26861.1 - 0.015 15.6 2.9 0.053 13.9 2.9 2.0 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 CAR26861.1 - 0.015 15.1 3.9 0.025 14.5 0.4 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR26861.1 - 0.91 9.4 5.4 0.22 11.4 1.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hydrolase_4 PF12146.8 CAR26862.1 - 3.6e-16 59.2 0.0 7.3e-09 35.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAR26862.1 - 4.4e-14 52.7 0.1 2e-07 31.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CAR26862.1 - 9.4e-07 28.5 0.0 2.2e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 CAR26862.1 - 0.00062 19.7 0.0 0.055 13.4 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 CAR26862.1 - 0.00068 19.3 0.0 0.0011 18.7 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 CAR26862.1 - 0.0025 17.4 0.0 0.022 14.3 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF829 PF05705.14 CAR26862.1 - 0.0087 16.0 0.0 1.3 8.9 0.0 2.3 1 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_2 PF02230.16 CAR26862.1 - 0.018 14.9 0.1 4.4 7.0 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.12 CAR26862.1 - 0.032 14.2 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) LIDHydrolase PF10230.9 CAR26862.1 - 0.041 13.4 0.8 3.9 6.9 0.0 2.3 2 1 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CAR26862.1 - 0.06 13.9 0.0 0.073 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF818 PF05677.12 CAR26862.1 - 0.061 12.3 0.1 0.098 11.6 0.1 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Esterase PF00756.20 CAR26862.1 - 0.093 12.4 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.12 CAR26862.1 - 0.16 10.6 0.0 0.43 9.2 0.0 1.6 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) IF4E PF01652.18 CAR26863.1 - 4e-53 179.5 0.5 4.8e-53 179.2 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Na_Ca_ex PF01699.24 CAR26864.1 - 9.3e-21 74.4 28.7 6.3e-15 55.4 13.8 3.7 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 CAR26864.1 - 4.7e-12 46.4 9.1 4.7e-12 46.4 9.1 3.9 3 0 0 3 3 3 1 Inner membrane component domain Na_K-ATPase PF00287.18 CAR26864.1 - 0.23 10.6 2.1 7.6 5.6 4.0 2.1 2 0 0 2 2 2 0 Sodium / potassium ATPase beta chain KRE1 PF17056.5 CAR26865.1 - 4.5e-22 77.6 7.0 4.5e-22 77.6 7.0 3.9 3 2 2 5 5 5 1 Killer toxin-resistance protein 1 Hamartin PF04388.12 CAR26865.1 - 6.4 5.3 18.0 7.4 5.1 18.0 1.2 1 0 0 1 1 1 0 Hamartin protein Aminotran_3 PF00202.21 CAR26866.1 - 1.1e-126 422.8 0.0 1.4e-126 422.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CAR26866.1 - 4.1e-05 22.9 0.0 6.4e-05 22.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Serine_rich PF08824.10 CAR26866.1 - 0.06 13.3 0.2 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Serine rich protein interaction domain Rhodanese PF00581.20 CAR26866.1 - 0.11 13.0 0.1 1.3 9.6 0.0 2.5 3 0 0 3 3 3 0 Rhodanese-like domain CDC50 PF03381.15 CAR26867.1 - 3.5e-80 269.5 0.8 4.5e-80 269.2 0.8 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3098 PF11297.8 CAR26867.1 - 0.0061 16.1 0.1 0.49 10.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3098) PBP1_TM PF14812.6 CAR26867.1 - 0.95 9.9 4.9 2.6 8.5 1.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LCM PF04072.14 CAR26868.1 - 3e-26 92.5 0.0 4.8e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_6 PF13964.6 CAR26868.1 - 3.1e-17 62.2 1.7 8.5e-08 32.2 0.1 5.2 5 1 1 6 6 6 3 Kelch motif Kelch_4 PF13418.6 CAR26868.1 - 4.3e-17 61.8 2.4 3.2e-12 46.3 0.1 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CAR26868.1 - 7e-08 32.6 0.1 5.5e-05 23.3 0.1 4.0 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CAR26868.1 - 8.6e-08 31.7 0.2 1.7e-06 27.5 0.1 3.0 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 CAR26868.1 - 0.00026 20.9 0.0 1.7 8.7 0.0 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 CAR26868.1 - 0.041 13.9 0.3 0.47 10.5 0.1 3.0 4 0 0 4 4 4 0 Kelch motif Syja_N PF02383.18 CAR26869.1 - 1e-79 268.2 0.5 1e-79 268.2 0.5 2.0 3 0 0 3 3 3 1 SacI homology domain KH_6 PF15985.5 CAR26870.1 - 2.2e-14 53.5 0.0 4.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 CAR26870.1 - 1.3e-08 34.6 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain E1_UFD PF09358.10 CAR26870.1 - 0.0086 16.8 0.0 0.018 15.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain DHHC PF01529.20 CAR26871.1 - 3.7e-33 114.5 12.3 3.7e-33 114.5 12.3 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Bac_surface_Ag PF01103.23 CAR26871.1 - 0.11 11.9 0.1 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Surface antigen UPF0114 PF03350.16 CAR26871.1 - 0.29 11.3 3.6 9.5 6.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 LPD24 PF18839.1 CAR26872.1 - 1.5 9.1 4.9 1.6e+02 2.6 0.1 4.2 4 0 0 4 4 4 0 Large polyvalent protein associated domain 24 DnaJ PF00226.31 CAR26873.1 - 0.00045 20.3 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CAR26873.1 - 0.021 14.9 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Pam16 AAA PF00004.29 CAR26874.1 - 1.3e-54 184.1 0.0 3.2e-43 147.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR26874.1 - 1.4e-10 40.8 0.0 3.5e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CAR26874.1 - 9.8e-06 26.1 0.3 0.047 14.1 0.0 3.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 CAR26874.1 - 7.1e-05 23.4 0.0 0.29 11.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 CAR26874.1 - 0.00011 22.0 0.0 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CAR26874.1 - 0.00011 22.4 0.1 0.22 11.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CAR26874.1 - 0.00022 21.5 0.0 0.035 14.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Parvo_NS1 PF01057.17 CAR26874.1 - 0.00049 19.3 0.0 0.00085 18.5 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 CAR26874.1 - 0.00082 19.5 0.0 0.87 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CAR26874.1 - 0.0034 16.9 0.0 0.014 14.9 0.0 2.0 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 CAR26874.1 - 0.0038 17.2 0.0 0.067 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 CAR26874.1 - 0.0044 17.0 0.4 0.038 14.0 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TsaE PF02367.17 CAR26874.1 - 0.0085 16.1 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 CAR26874.1 - 0.014 15.5 0.0 0.098 12.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 CAR26874.1 - 0.015 15.7 0.0 3.5 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 CAR26874.1 - 0.02 14.6 0.1 18 5.0 0.0 3.1 3 0 0 3 3 3 0 Cytidylate kinase IstB_IS21 PF01695.17 CAR26874.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 CAR26874.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 KaiC TIP49 PF06068.13 CAR26874.1 - 0.024 13.9 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 CAR26874.1 - 0.027 13.9 0.1 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CAR26874.1 - 0.028 14.5 0.0 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 CAR26874.1 - 0.051 13.4 0.0 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PPV_E1_C PF00519.17 CAR26874.1 - 0.053 12.3 0.2 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Papillomavirus helicase PhoH PF02562.16 CAR26874.1 - 0.087 12.3 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.6 CAR26874.1 - 0.12 12.1 0.1 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CAR26874.1 - 0.12 12.6 0.0 0.76 10.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain SKI PF01202.22 CAR26874.1 - 0.18 11.9 0.0 7.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_25 PF13481.6 CAR26874.1 - 0.2 11.2 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Hist_deacetyl PF00850.19 CAR26875.1 - 7.3e-83 278.6 0.0 1.1e-82 277.9 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DMRL_synthase PF00885.19 CAR26876.1 - 7.7e-51 171.6 0.1 9.3e-51 171.4 0.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RRM_1 PF00076.22 CAR26877.1 - 0.01 15.7 1.9 0.011 15.5 0.3 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_1 PF00515.28 CAR26878.1 - 2e-23 81.2 30.1 4.4e-06 26.3 0.0 11.8 13 0 0 13 13 13 7 Tetratricopeptide repeat TPR_12 PF13424.6 CAR26878.1 - 1.7e-21 76.3 21.8 6.2e-07 29.6 0.1 10.2 8 3 3 11 11 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 CAR26878.1 - 3e-21 73.8 33.4 0.00049 20.0 0.0 12.7 15 1 1 16 16 13 6 Tetratricopeptide repeat TPR_14 PF13428.6 CAR26878.1 - 1.1e-17 63.2 11.5 0.19 12.7 0.0 12.0 8 3 4 12 12 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAR26878.1 - 1.6e-17 63.9 3.5 0.00013 22.6 0.0 8.3 8 2 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 CAR26878.1 - 1.2e-14 53.2 28.6 0.0092 16.1 0.0 12.3 13 1 1 14 14 13 4 Tetratricopeptide repeat TPR_19 PF14559.6 CAR26878.1 - 1.6e-14 54.2 8.1 0.0026 18.3 0.1 10.3 9 2 1 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR26878.1 - 1.1e-11 44.7 11.5 0.00027 21.1 0.0 6.5 5 2 2 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CAR26878.1 - 3.4e-11 43.0 19.2 0.52 11.1 0.0 11.2 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAR26878.1 - 2.2e-07 30.4 12.7 1.2 9.4 0.0 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAR26878.1 - 6.2e-07 29.4 12.0 20 5.8 0.0 11.2 12 0 0 12 12 12 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR26878.1 - 1e-05 25.5 3.0 1.7 8.8 0.1 6.4 7 0 0 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 CAR26878.1 - 0.011 15.4 23.8 0.045 13.4 0.2 8.6 9 1 1 10 10 10 0 TPR repeat TPR_9 PF13371.6 CAR26878.1 - 0.012 15.8 0.9 14 6.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Lipoprotein_10 PF03202.13 CAR26878.1 - 0.027 14.9 0.4 0.027 14.9 0.4 4.5 4 1 0 4 4 3 0 Putative mycoplasma lipoprotein, C-terminal region TPR_10 PF13374.6 CAR26878.1 - 8.7 6.4 22.9 9.8 6.2 0.1 8.7 11 0 0 11 11 10 0 Tetratricopeptide repeat Sld5 PF05916.11 CAR26879.1 - 3e-18 66.3 0.0 3.8e-18 65.9 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein PEX11 PF05648.14 CAR26880.1 - 7.3e-55 185.8 3.8 8.2e-55 185.7 3.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Glutaredoxin2_C PF04399.13 CAR26880.1 - 0.16 11.8 0.8 11 5.9 0.1 2.9 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain Spt20 PF12090.8 CAR26881.1 - 5.1e-62 209.5 8.1 5.1e-62 209.5 8.1 4.9 4 1 0 4 4 4 1 Spt20 family RskA PF10099.9 CAR26881.1 - 0.0068 16.7 4.6 0.0068 16.7 4.6 2.6 2 1 0 2 2 2 1 Anti-sigma-K factor rskA TFIIA PF03153.13 CAR26881.1 - 0.018 15.1 47.4 0.33 10.9 12.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cache_3-Cache_2 PF17201.4 CAR26881.1 - 2 7.6 12.9 0.12 11.7 3.9 2.4 2 0 0 2 2 2 0 Cache 3/Cache 2 fusion domain DCP1 PF06058.13 CAR26882.1 - 2.7e-26 91.8 0.0 5e-24 84.5 0.0 2.5 1 1 0 1 1 1 1 Dcp1-like decapping family GFO_IDH_MocA PF01408.22 CAR26883.1 - 3.6e-20 73.0 0.0 5.8e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CAR26883.1 - 2.3e-08 34.0 0.0 3.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain TrmB PF01978.19 CAR26883.1 - 0.088 12.7 0.1 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF5300 PF17224.3 CAR26883.1 - 0.12 12.7 0.4 2.2 8.6 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF5300) Hydantoinase_B PF02538.14 CAR26884.1 - 1.1e-204 680.7 0.0 1.4e-204 680.4 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CAR26884.1 - 3e-98 328.7 0.7 4.1e-98 328.2 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CAR26884.1 - 1e-57 194.8 0.2 1.1e-55 188.1 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region HMG_box PF00505.19 CAR26885.1 - 2.4e-11 43.9 3.0 2.4e-11 43.9 3.0 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CAR26885.1 - 8.4e-08 32.7 2.8 8.4e-08 32.7 2.8 2.3 2 1 1 3 3 3 1 HMG-box domain Transketolase_N PF00456.21 CAR26885.1 - 0.022 13.8 0.6 0.027 13.4 0.6 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DUF908 PF06012.12 CAR26885.1 - 0.35 10.2 2.9 0.33 10.3 2.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MRP-S28 PF10213.9 CAR26886.1 - 4.1e-51 172.7 2.6 1.3e-50 171.1 2.7 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Ada3 PF10198.9 CAR26887.1 - 1.6e-46 157.8 1.0 4.3e-46 156.3 1.0 1.8 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 UQ_con PF00179.26 CAR26888.1 - 9.5e-44 148.5 0.0 1.2e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 CAR26888.1 - 4.7e-27 93.6 0.3 8.5e-27 92.7 0.3 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain GGA_N-GAT PF18308.1 CAR26888.1 - 0.31 10.7 1.1 3.1 7.5 0.3 2.4 2 0 0 2 2 2 0 GGA N-GAT domain Peptidase_M16 PF00675.20 CAR26889.1 - 4.6e-50 169.5 0.0 9.6e-50 168.4 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CAR26889.1 - 2.5e-36 125.4 0.0 6.5e-36 124.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain CybS PF05328.12 CAR26890.1 - 7.6e-50 168.0 0.0 9.2e-50 167.8 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit eIF3m_C_helix PF18005.1 CAR26891.1 - 0.12 12.1 0.5 0.23 11.2 0.5 1.5 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix PXA PF02194.15 CAR26892.1 - 6e-11 42.6 1.1 9.5e-10 38.7 1.1 2.4 1 1 0 1 1 1 1 PXA domain PseudoU_synth_2 PF00849.22 CAR26893.1 - 4.6e-19 69.1 0.6 7e-18 65.2 0.6 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase Nipped-B_C PF12830.7 CAR26894.1 - 6.1e-40 137.2 1.7 2e-39 135.5 0.4 2.5 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 CAR26894.1 - 2.2e-14 53.4 0.7 1e-13 51.3 0.7 2.3 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion SAS4 PF15460.6 CAR26895.1 - 5.6e-27 93.7 8.1 5.6e-27 93.7 8.1 2.3 3 0 0 3 3 3 1 Something about silencing, SAS, complex subunit 4 DUF4484 PF14831.6 CAR26895.1 - 0.17 11.9 3.4 0.25 11.3 3.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Metallophos PF00149.28 CAR26896.1 - 1.7e-11 45.0 1.5 2.7e-11 44.3 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UreD PF01774.17 CAR26896.1 - 0.22 11.4 0.0 0.52 10.2 0.0 1.6 1 1 0 1 1 1 0 UreD urease accessory protein Sec10 PF07393.11 CAR26897.1 - 1e-198 662.2 19.4 1.4e-198 661.7 19.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF3837 PF12939.7 CAR26897.1 - 0.072 13.5 0.8 10 6.6 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) DUF1664 PF07889.12 CAR26897.1 - 0.32 11.1 3.1 0.94 9.5 3.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 CAR26897.1 - 0.38 11.5 3.6 1.1 10.0 1.4 3.0 2 1 0 2 2 2 0 Occludin homology domain Thioredoxin PF00085.20 CAR26898.1 - 4.6e-08 33.0 0.0 8.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 CAR26898.1 - 4.7e-07 29.0 0.4 6.1e-07 28.6 0.4 1.1 1 0 0 1 1 1 1 Phosducin PI3K_P85_iSH2 PF16454.5 CAR26898.1 - 0.058 13.0 3.4 0.096 12.3 3.4 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ubiquitin PF00240.23 CAR26899.1 - 7.7e-34 115.3 0.6 7.7e-34 115.3 0.6 1.8 2 1 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 CAR26899.1 - 7.8e-23 80.4 2.3 7.8e-23 80.4 2.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CAR26899.1 - 7.7e-17 60.9 1.8 4.7e-16 58.4 0.7 2.2 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAR26899.1 - 2.3e-05 24.8 0.1 0.00012 22.4 0.1 2.1 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAR26899.1 - 0.0012 18.9 0.6 0.0028 17.7 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CAR26899.1 - 0.0033 17.7 0.4 0.0077 16.6 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CAR26899.1 - 0.0051 16.7 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CAR26899.1 - 0.012 16.2 0.5 0.016 15.8 0.5 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CAR26899.1 - 0.019 15.0 1.0 5.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 CAR26899.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain HypA PF01155.19 CAR26899.1 - 0.2 11.7 1.0 0.29 11.2 1.0 1.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DNA_RNApol_7kD PF03604.13 CAR26899.1 - 0.36 10.5 4.6 1.3 8.7 1.1 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_4 PF13717.6 CAR26899.1 - 9.5 6.2 7.2 5.2 7.1 0.4 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Pga1 PF10333.9 CAR26900.1 - 0.21 11.4 2.2 0.33 10.8 2.2 1.3 1 0 0 1 1 1 0 GPI-Mannosyltransferase II co-activator DUF600 PF04634.12 CAR26900.1 - 0.23 11.5 3.1 0.13 12.3 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF600 PRELI PF04707.14 CAR26901.1 - 3e-56 189.6 0.5 3.6e-56 189.4 0.5 1.1 1 0 0 1 1 1 1 PRELI-like family DHHC PF01529.20 CAR26902.1 - 6.2e-34 117.0 9.2 6.2e-34 117.0 9.2 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase TadE PF07811.12 CAR26902.1 - 0.53 10.6 2.2 2 8.8 0.0 2.7 2 1 0 2 2 2 0 TadE-like protein NOA36 PF06524.12 CAR26903.1 - 0.064 12.6 10.0 0.13 11.6 10.0 1.4 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 CAR26903.1 - 0.091 13.0 13.3 2.1 8.5 9.5 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 YL1 PF05764.13 CAR26903.1 - 1 9.4 10.9 0.34 11.0 7.7 1.9 2 0 0 2 2 2 0 YL1 nuclear protein RXT2_N PF08595.11 CAR26903.1 - 1.4 8.9 7.6 1.9 8.5 4.2 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.6 CAR26903.1 - 2.3 8.7 13.4 15 6.0 13.4 2.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAP_alpha PF03896.16 CAR26903.1 - 5.3 6.1 6.5 13 4.9 6.5 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPP4R2 PF09184.11 CAR26903.1 - 9.4 5.7 17.2 0.3 10.7 9.0 2.1 2 0 0 2 2 2 0 PPP4R2 dCMP_cyt_deam_1 PF00383.23 CAR26904.1 - 5.5e-17 61.5 0.2 6.5e-17 61.3 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CAR26904.1 - 2.8e-10 40.5 0.7 2.7e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CAR26904.1 - 0.00077 19.1 0.5 1 9.0 0.2 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases DUF2521 PF10730.9 CAR26904.1 - 0.0055 16.7 0.0 0.0073 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2521) Peptidase_M24 PF00557.24 CAR26905.1 - 1.1e-51 175.5 0.1 1.4e-51 175.2 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CAR26905.1 - 9.3e-17 61.1 5.0 9.3e-17 61.1 5.0 1.8 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding ATP-cone PF03477.16 CAR26905.1 - 0.068 13.7 0.0 14 6.4 0.0 2.4 2 0 0 2 2 2 0 ATP cone domain zf-MYND PF01753.18 CAR26905.1 - 8.4 6.6 13.7 0.09 12.9 4.3 2.6 3 0 0 3 3 3 0 MYND finger Cpn60_TCP1 PF00118.24 CAR26906.1 - 1.3e-155 518.8 1.3 1.4e-155 518.6 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sec1 PF00995.23 CAR26907.1 - 1.3e-124 417.6 3.0 1.5e-124 417.4 3.0 1.0 1 0 0 1 1 1 1 Sec1 family RAC_head PF16717.5 CAR26907.1 - 6.9 7.7 6.5 24 6.0 0.0 3.6 3 2 0 3 3 3 0 Ribosome-associated complex head domain TIP49 PF06068.13 CAR26908.1 - 2.4e-168 559.8 0.3 2.9e-168 559.5 0.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CAR26908.1 - 6.1e-23 80.7 0.0 1.8e-22 79.3 0.0 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CAR26908.1 - 1.6e-08 35.1 0.7 5.9e-05 23.5 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CAR26908.1 - 5.1e-08 32.8 0.1 1.8e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CAR26908.1 - 0.00073 19.8 0.2 0.0022 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CAR26908.1 - 0.004 17.5 0.6 3.8 7.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CAR26908.1 - 0.018 15.5 0.1 0.098 13.0 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain DnaB_C PF03796.15 CAR26908.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 CAR26908.1 - 0.032 13.6 0.1 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CPT PF07931.12 CAR26908.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_5 PF07728.14 CAR26908.1 - 0.053 13.5 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 CAR26908.1 - 0.068 12.5 0.1 0.17 11.1 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 CAR26908.1 - 0.13 12.0 0.0 16 5.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain PCP_red PF08369.10 CAR26908.1 - 0.17 12.1 0.7 16 5.8 0.1 2.7 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit SIR2 PF02146.17 CAR26909.1 - 1.6e-28 99.8 0.1 3e-28 98.9 0.1 1.4 1 1 0 1 1 1 1 Sir2 family ATP_bind_1 PF03029.17 CAR26910.1 - 5.8e-88 294.7 0.0 6.6e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 CAR26910.1 - 0.0013 17.8 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CAR26910.1 - 0.0025 18.4 0.0 0.0047 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CAR26910.1 - 0.0056 16.6 0.1 0.07 13.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CAR26910.1 - 0.0075 16.3 0.0 0.027 14.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CAR26910.1 - 0.0088 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_10 PF12846.7 CAR26910.1 - 0.013 14.4 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.14 CAR26910.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 CAR26910.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 CAR26910.1 - 0.019 14.7 0.0 0.06 13.1 0.0 1.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ABC_tran PF00005.27 CAR26910.1 - 0.026 15.1 0.0 0.05 14.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 CAR26910.1 - 0.028 14.0 0.0 0.83 9.2 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CAR26910.1 - 0.028 14.7 0.0 0.12 12.6 0.0 2.0 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CAR26910.1 - 0.039 13.1 0.1 0.065 12.4 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 CAR26910.1 - 0.044 13.5 0.0 0.098 12.4 0.0 1.5 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.6 CAR26910.1 - 0.05 13.9 0.0 0.19 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAR26910.1 - 0.05 13.1 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CAR26910.1 - 0.093 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 CAR26910.1 - 0.096 12.7 0.0 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CAR26910.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 CAR26910.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 CAR26910.1 - 0.14 12.3 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain T2SSE PF00437.20 CAR26910.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 CAR26910.1 - 0.17 11.5 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Fer4_NifH PF00142.18 CAR26910.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_17 PF13207.6 CAR26910.1 - 0.19 12.2 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR26910.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 CAR26910.1 - 0.23 11.6 0.0 0.43 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf_CCCH_4 PF18345.1 CAR26911.1 - 5.9e-07 29.3 8.4 1.2e-06 28.3 8.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CAR26911.1 - 1.7e-06 27.8 4.5 1.7e-06 27.8 4.5 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CAR26911.1 - 2.7e-06 27.0 3.6 5.4e-06 26.1 3.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 CAR26911.1 - 0.03 15.0 1.2 0.03 15.0 1.2 2.0 2 0 0 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 CAR26911.1 - 0.074 13.5 5.2 0.15 12.6 5.2 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CAR26911.1 - 0.16 12.2 0.6 0.38 11.0 0.6 1.5 1 0 0 1 1 1 0 Zinc-finger containing family Arv1 PF04161.13 CAR26912.1 - 1.1e-62 212.0 10.7 1.5e-62 211.5 10.7 1.2 1 0 0 1 1 1 1 Arv1-like family RSN1_7TM PF02714.15 CAR26913.1 - 1.7e-83 280.1 24.4 1.7e-83 280.1 24.4 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CAR26913.1 - 1.1e-39 135.7 3.6 1.1e-39 135.7 3.6 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CAR26913.1 - 4e-34 118.4 0.0 1.3e-33 116.8 0.0 1.8 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PI3Ka PF00613.20 CAR26914.1 - 4.3e-70 234.9 2.1 6.9e-70 234.2 2.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CAR26914.1 - 4.8e-51 174.0 0.0 2.7e-34 119.1 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CAR26914.1 - 1.5e-22 80.0 0.2 3.7e-22 78.8 0.2 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DEAD PF00270.29 CAR26915.1 - 2.4e-40 138.2 0.4 4.4e-40 137.3 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR26915.1 - 8.5e-23 80.8 0.0 2.2e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR26915.1 - 3.9e-08 33.5 0.1 7.4e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CAR26915.1 - 0.0061 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAR26915.1 - 0.11 12.8 0.3 0.4 11.0 0.3 2.0 1 1 0 1 1 1 0 AAA domain DUF3038 PF11237.8 CAR26916.1 - 0.14 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) CoaE PF01121.20 CAR26917.1 - 8.6e-58 194.9 0.0 1.1e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CAR26917.1 - 0.00025 21.6 0.0 0.0013 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR26917.1 - 0.00098 19.3 0.0 0.0017 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CAR26917.1 - 0.0012 19.2 0.0 0.0021 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CAR26917.1 - 0.0035 17.8 0.0 0.008 16.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain SKI PF01202.22 CAR26917.1 - 0.018 15.2 0.0 0.045 13.9 0.0 1.6 2 0 0 2 2 2 0 Shikimate kinase Spore_IV_A PF09547.10 CAR26917.1 - 0.046 12.7 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Cytidylate_kin2 PF13189.6 CAR26917.1 - 0.05 13.7 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family PRK PF00485.18 CAR26917.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ApbA_C PF08546.11 CAR26918.1 - 2.1e-14 53.8 0.0 1.2e-13 51.3 0.0 2.2 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal SET PF00856.28 CAR26919.1 - 0.0013 19.2 0.0 0.0027 18.1 0.0 1.6 1 1 0 1 1 1 1 SET domain BPL_LplA_LipB PF03099.19 CAR26920.1 - 2.8e-17 62.8 0.0 5.6e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family NMD3 PF04981.13 CAR26920.1 - 0.028 13.9 0.2 2.3 7.6 0.0 2.6 3 0 0 3 3 3 0 NMD3 family Recep_L_domain PF01030.24 CAR26920.1 - 0.045 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Receptor L domain FHA PF00498.26 CAR26921.1 - 1.5e-20 73.3 0.6 5e-19 68.4 0.4 2.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CAR26921.1 - 1.8e-06 28.2 0.0 6.2e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4781 PF16013.5 CAR26921.1 - 5.2 5.8 8.5 0.81 8.4 4.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4781) DASH_Spc19 PF08287.11 CAR26922.1 - 3.4e-34 118.0 12.7 4e-34 117.8 12.7 1.0 1 0 0 1 1 1 1 Spc19 Telomere_reg-2 PF10193.9 CAR26922.1 - 0.25 11.8 6.5 1.6 9.2 2.5 2.7 1 1 1 2 2 2 0 Telomere length regulation protein bZIP_2 PF07716.15 CAR26922.1 - 0.3 11.2 0.2 0.3 11.2 0.2 3.5 3 0 0 3 3 3 0 Basic region leucine zipper FlaC_arch PF05377.11 CAR26922.1 - 0.71 10.3 5.5 5.3 7.5 0.0 3.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Rogdi_lz PF10259.9 CAR26923.1 - 1.4e-64 218.2 1.7 1.5e-64 218.0 1.7 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Matrilin_ccoil PF10393.9 CAR26923.1 - 0.049 13.5 1.4 8.5 6.3 1.3 3.0 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Coq4 PF05019.13 CAR26924.1 - 3.8e-92 307.6 0.0 4.7e-92 307.3 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Transp_cyt_pur PF02133.15 CAR26925.1 - 1.6e-70 238.1 33.5 1.6e-70 238.1 33.5 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.21 CAR26926.1 - 2.1e-46 158.2 12.5 2.1e-46 158.2 12.5 2.1 2 0 0 2 2 2 1 Cation efflux family RXT2_N PF08595.11 CAR26926.1 - 0.0024 17.9 4.2 0.0025 17.9 0.8 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal CSG2 PF16965.5 CAR26926.1 - 0.0072 15.3 0.1 0.0072 15.3 0.1 2.9 3 0 0 3 3 3 1 Ceramide synthase regulator DUF4834 PF16118.5 CAR26926.1 - 0.011 16.7 12.3 0.028 15.4 2.0 4.0 4 0 0 4 4 3 0 Domain of unknown function (DUF4834) FHIPEP PF00771.20 CAR26926.1 - 0.019 13.4 0.5 0.048 12.1 0.5 1.6 1 0 0 1 1 1 0 FHIPEP family Connexin PF00029.19 CAR26926.1 - 0.026 14.3 1.9 0.042 13.6 0.1 2.2 3 0 0 3 3 2 0 Connexin V_ATPase_I PF01496.19 CAR26926.1 - 0.037 12.0 3.8 0.03 12.3 0.9 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PepSY_TM PF03929.16 CAR26926.1 - 0.039 13.6 1.4 0.22 11.1 0.4 2.6 3 0 0 3 3 3 0 PepSY-associated TM region EOS1 PF12326.8 CAR26926.1 - 0.044 13.7 2.8 4.4 7.2 1.5 2.9 2 1 0 3 3 3 0 N-glycosylation protein CPSF100_C PF13299.6 CAR26926.1 - 0.048 13.8 0.7 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3464 PF11947.8 CAR26926.1 - 0.056 13.2 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Plasmodium_Vir PF05795.11 CAR26926.1 - 0.076 12.4 0.9 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 Plasmodium vivax Vir protein FAM176 PF14851.6 CAR26926.1 - 0.14 11.8 6.7 0.061 13.0 0.8 2.5 2 0 0 2 2 2 0 FAM176 family EphA2_TM PF14575.6 CAR26926.1 - 0.16 12.9 0.9 2.2 9.2 0.3 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain BORG_CEP PF14957.6 CAR26926.1 - 0.22 12.7 2.3 10 7.3 0.0 2.7 3 0 0 3 3 2 0 Cdc42 effector SelP_N PF04592.14 CAR26926.1 - 0.25 10.7 31.0 0.35 10.3 0.2 3.2 3 0 0 3 3 3 0 Selenoprotein P, N terminal region Rpp20 PF12328.8 CAR26926.1 - 0.4 10.6 3.5 0.8 9.7 3.5 1.5 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P RskA PF10099.9 CAR26926.1 - 0.43 10.9 3.2 0.88 9.8 3.2 1.6 1 1 0 1 1 1 0 Anti-sigma-K factor rskA RED_N PF07808.13 CAR26926.1 - 0.63 9.6 9.7 1.1 8.9 9.7 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Pex14_N PF04695.13 CAR26926.1 - 0.95 10.1 12.2 0.076 13.7 3.1 3.1 4 0 0 4 4 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM51 PF15345.6 CAR26926.1 - 1.3 8.8 6.2 3.9 7.2 6.2 1.7 1 0 0 1 1 1 0 Transmembrane protein 51 Suf PF05843.14 CAR26926.1 - 1.5 8.8 6.4 0.32 10.9 2.8 1.7 2 0 0 2 2 1 0 Suppressor of forked protein (Suf) CPP1-like PF11833.8 CAR26926.1 - 2.9 7.5 11.6 0.27 10.9 1.4 3.2 2 1 1 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like HA2 PF04408.23 CAR26926.1 - 4.9 7.5 5.8 5.3 7.4 3.9 2.0 2 1 0 2 2 1 0 Helicase associated domain (HA2) OATP PF03137.20 CAR26926.1 - 5.9 5.0 15.0 0.014 13.7 3.2 2.3 2 2 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MTABC_N PF16185.5 CAR26926.1 - 6.5 6.2 8.2 0.79 9.2 0.2 3.0 3 0 0 3 3 3 0 Mitochondrial ABC-transporter N-terminal five TM region DUF2946 PF11162.8 CAR26926.1 - 6.8 7.4 13.9 34 5.1 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) Afi1 PF07792.12 CAR26926.1 - 7.2 7.1 9.3 34 4.9 5.1 2.5 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF5421 PF17458.2 CAR26926.1 - 9.9 5.5 11.0 19 4.5 11.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5421) Topoisom_bac PF01131.20 CAR26927.1 - 1.5e-104 350.3 0.0 2.2e-104 349.8 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CAR26927.1 - 1e-19 70.6 0.0 2.2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain EST1_DNA_bind PF10373.9 CAR26928.1 - 6.4e-64 216.1 2.5 8.3e-64 215.8 0.2 2.3 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CAR26928.1 - 2.3e-20 73.6 0.3 9e-20 71.7 0.3 2.1 1 0 0 1 1 1 1 Telomerase activating protein Est1 Zn_clus PF00172.18 CAR26929.1 - 1.9e-08 34.3 7.6 3.3e-08 33.5 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.19 CAR26930.1 - 3.9e-12 45.8 0.0 4.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PIP5K PF01504.18 CAR26931.1 - 8.5e-92 307.2 0.5 8.5e-92 307.2 0.5 2.3 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Rep_4 PF05797.11 CAR26932.1 - 2.4e-203 674.7 0.0 2.9e-203 674.4 0.0 1.0 1 0 0 1 1 1 1 Yeast trans-acting factor (REP1/REP2) CYSTM PF12734.7 CAR26933.1 - 2.5e-08 34.1 44.3 0.00085 19.6 44.3 3.3 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance DUF2076 PF09849.9 CAR26933.1 - 0.15 12.1 1.8 0.14 12.2 1.8 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CPSase_L_D2 PF02786.17 CAR26934.1 - 2.1e-81 272.4 0.2 3.5e-81 271.7 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CAR26934.1 - 1e-67 227.8 0.0 1.6e-67 227.1 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CAR26934.1 - 8.4e-39 132.5 0.1 1.7e-38 131.5 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CAR26934.1 - 1.2e-32 112.3 0.0 1.2e-31 108.9 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CAR26934.1 - 2.5e-25 89.6 0.0 5e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CAR26934.1 - 9.5e-19 67.0 3.2 9.5e-19 67.0 3.2 2.5 3 0 0 3 3 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CAR26934.1 - 7.4e-06 25.7 3.8 0.027 14.3 0.2 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CAR26934.1 - 2.8e-05 23.7 0.0 6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CAR26934.1 - 4.7e-05 23.0 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CAR26934.1 - 0.0001 22.4 0.0 0.00029 20.9 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 CAR26934.1 - 0.00063 20.4 0.7 0.56 10.9 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 CAR26934.1 - 0.0034 16.6 0.4 0.35 10.1 0.1 2.5 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 CAR26934.1 - 0.086 12.1 0.0 0.24 10.6 0.0 1.7 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 CAR26934.1 - 0.15 12.0 3.6 2.3 8.2 1.1 3.1 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DASH_Duo1 PF08651.10 CAR26935.1 - 1.6e-23 82.3 0.3 4.4e-23 80.8 0.2 1.7 2 0 0 2 2 2 1 DASH complex subunit Duo1 DUF755 PF05501.11 CAR26935.1 - 0.13 12.6 7.2 0.16 12.3 4.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF755) Tweety PF04906.13 CAR26935.1 - 0.14 10.8 0.6 0.17 10.5 0.6 1.2 1 0 0 1 1 1 0 Tweety APG12 PF04110.13 CAR26936.1 - 8.2e-27 93.4 0.6 1.7e-26 92.4 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 Kinetochor_Ybp2 PF08568.10 CAR26937.1 - 2.1e-152 508.9 16.1 2.3e-152 508.7 16.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HUN PF08729.10 CAR26938.1 - 2.1e-08 34.0 0.0 7.6e-08 32.2 0.0 2.1 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Na_trans_assoc PF06512.13 CAR26938.1 - 0.00091 19.6 0.0 0.00091 19.6 0.0 3.5 2 2 1 3 3 3 1 Sodium ion transport-associated DUF1764 PF08576.10 CAR26938.1 - 0.016 16.1 1.0 0.016 16.1 1.0 5.4 4 1 0 4 4 4 0 Eukaryotic protein of unknown function (DUF1764) BCDHK_Adom3 PF10436.9 CAR26939.1 - 2e-29 102.5 0.3 4e-29 101.5 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CAR26939.1 - 9.3e-06 26.1 0.0 0.00017 22.0 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UQ_con PF00179.26 CAR26940.1 - 6.2e-51 171.7 0.1 7.2e-51 171.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAR26940.1 - 0.0089 15.7 0.0 0.017 14.9 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CAR26940.1 - 0.036 14.4 0.1 0.073 13.4 0.1 1.7 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 CAR26940.1 - 0.062 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain Leuk-A4-hydro_C PF09127.11 CAR26940.1 - 0.075 13.1 0.1 1 9.5 0.1 2.1 1 1 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal MTS_N PF08468.11 CAR26941.1 - 0.074 13.1 0.2 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal SirA PF10747.9 CAR26941.1 - 0.27 11.6 2.0 0.44 10.9 2.0 1.3 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA CBS PF00571.28 CAR26942.1 - 7.5e-21 74.3 1.3 3e-05 24.4 0.0 5.3 5 0 0 5 5 5 4 CBS domain Macoilin PF09726.9 CAR26942.1 - 0.6 8.6 5.8 0.67 8.4 5.8 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 CAR26942.1 - 0.63 8.7 7.3 0.99 8.0 7.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3682 PF12446.8 CAR26942.1 - 10 6.6 33.5 0.16 12.4 16.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3682) FA_desaturase PF00487.24 CAR26943.1 - 4e-19 69.4 14.8 4e-19 69.4 14.8 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CAR26943.1 - 1.6e-14 53.8 0.0 3.4e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_7 PF13241.6 CAR26944.1 - 1.7e-24 86.2 0.0 2.6e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CAR26944.1 - 2e-19 69.0 0.2 3.6e-19 68.2 0.2 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 CAR26944.1 - 9.2e-12 44.2 0.0 1.8e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 CAR26944.1 - 0.0052 16.9 0.0 0.0092 16.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CAR26944.1 - 0.048 13.0 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.22 CAR26945.1 - 1e-41 140.6 0.0 1.6e-17 63.1 0.0 4.5 6 0 0 6 6 6 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR26945.1 - 0.0045 16.9 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CAR26945.1 - 0.0062 16.1 0.0 0.043 13.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR26945.1 - 0.0079 16.3 3.0 0.011 15.9 0.0 2.8 4 1 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 CAR26945.1 - 0.014 15.4 0.0 0.014 15.4 0.0 2.7 3 1 0 3 3 3 0 RNA binding motif DUF4407 PF14362.6 CAR26945.1 - 0.15 11.3 13.2 0.28 10.5 13.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAD-oxidase_C PF02913.19 CAR26945.1 - 1.2 8.7 6.3 2.2 7.9 6.3 1.3 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain B277 PF17623.2 CAR26945.1 - 4.7 6.2 6.6 8.7 5.3 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function IZUMO PF15005.6 CAR26946.1 - 0.019 15.5 3.5 0.022 15.3 2.7 1.5 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated APG6_N PF17675.1 CAR26946.1 - 0.025 15.1 8.6 0.041 14.4 8.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region ERGIC_N PF13850.6 CAR26946.1 - 0.093 13.1 0.1 0.16 12.3 0.1 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Imm26 PF15428.6 CAR26946.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 26 YlqD PF11068.8 CAR26946.1 - 1.9 8.9 8.3 0.71 10.3 4.3 2.2 2 1 0 2 2 2 0 YlqD protein Cornichon PF03311.14 CAR26947.1 - 1.8e-48 163.8 12.0 2.2e-48 163.6 12.0 1.1 1 0 0 1 1 1 1 Cornichon protein Bac_export_2 PF01312.19 CAR26947.1 - 0.93 8.6 5.0 1.2 8.2 5.0 1.3 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family DUF5305 PF17231.2 CAR26948.1 - 0.00048 19.6 0.3 0.001 18.5 0.0 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5305) WSC PF01822.19 CAR26948.1 - 0.00093 19.3 5.3 0.0023 18.1 5.3 1.6 1 0 0 1 1 1 1 WSC domain DUF2408 PF10303.9 CAR26949.1 - 1.2e-65 220.2 23.6 2.5e-45 154.4 1.7 5.2 3 2 2 5 5 5 5 Protein of unknown function (DUF2408) Ndc1_Nup PF09531.10 CAR26949.1 - 5.5 5.6 8.5 0.33 9.6 0.1 2.4 2 1 1 3 3 3 0 Nucleoporin protein Ndc1-Nup AhpC-TSA PF00578.21 CAR26950.1 - 3.4e-27 94.8 0.0 4.6e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAR26950.1 - 3.6e-18 65.7 0.0 5.5e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 CAR26950.1 - 0.035 14.2 0.0 0.05 13.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF1644 PF07800.12 CAR26950.1 - 6.6 6.8 6.4 0.63 10.1 1.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1644) Adap_comp_sub PF00928.21 CAR26951.1 - 4.1e-88 295.2 1.2 5.4e-88 294.8 1.2 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CAR26951.1 - 8.9e-07 28.9 1.2 1.8e-06 27.9 0.9 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 CAR26951.1 - 0.033 13.6 0.1 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain TPP1 PF10341.9 CAR26952.1 - 6.3e-05 22.9 0.0 8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD HMGL-like PF00682.19 CAR26953.1 - 1.9e-80 270.2 0.0 2.5e-80 269.8 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 CAR26953.1 - 1.1e-20 73.9 0.0 2.1e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Urm1 PF09138.11 CAR26954.1 - 2.4e-35 120.7 0.4 2.7e-35 120.6 0.4 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CAR26954.1 - 0.00064 20.3 0.0 0.0008 20.0 0.0 1.2 1 0 0 1 1 1 1 ThiS family adh_short PF00106.25 CAR26954.1 - 0.029 13.8 0.0 0.038 13.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Cupin_2 PF07883.11 CAR26954.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Nas2_N PF18265.1 CAR26955.1 - 2.5e-20 72.2 2.0 4.2e-20 71.4 2.0 1.4 1 0 0 1 1 1 1 Nas2 N_terminal domain GRASP55_65 PF04495.14 CAR26955.1 - 4e-05 24.0 0.0 8.8e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 CAR26955.1 - 5e-05 23.1 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CAR26955.1 - 0.00016 22.0 0.1 0.0004 20.7 0.1 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CAR26955.1 - 0.0071 16.7 0.1 0.037 14.4 0.1 2.0 2 0 0 2 2 2 1 PDZ domain DUF883 PF05957.13 CAR26955.1 - 0.037 14.6 1.5 0.78 10.4 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 CAR26955.1 - 0.078 12.8 2.3 1.3 8.9 0.5 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Porin_3 PF01459.22 CAR26956.1 - 2.8e-85 286.1 0.2 3.2e-85 285.9 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Med9 PF07544.13 CAR26957.1 - 4.9e-27 93.8 0.7 6.3e-27 93.5 0.7 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 PEPCK_GTP PF00821.18 CAR26957.1 - 0.11 11.3 0.1 0.13 11.0 0.1 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain ERG2_Sigma1R PF04622.12 CAR26958.1 - 2.4e-92 308.0 0.4 2.8e-92 307.8 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Whi5 PF08528.11 CAR26959.1 - 2.7e-11 42.8 1.5 4.8e-11 42.0 1.5 1.4 1 0 0 1 1 1 1 Whi5 like PID_2 PF14719.6 CAR26959.1 - 0.0013 18.7 1.4 0.0029 17.5 1.1 1.7 1 1 1 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) ThiD2 PF17792.1 CAR26959.1 - 0.068 13.6 0.1 0.14 12.7 0.1 1.5 1 0 0 1 1 1 0 ThiD2 family DUF3439 PF11921.8 CAR26959.1 - 0.25 11.3 4.2 0.43 10.5 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LCAT PF02450.15 CAR26960.1 - 2e-125 419.0 0.2 2.6e-125 418.6 0.2 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CAR26960.1 - 0.00065 20.4 0.0 0.0015 19.1 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF1749 PF08538.10 CAR26960.1 - 0.0095 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 CAR26960.1 - 0.042 13.1 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_2 PF01674.18 CAR26960.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_1 PF00561.20 CAR26960.1 - 0.056 13.1 0.1 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF900 PF05990.12 CAR26960.1 - 0.082 12.4 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) CRA PF06589.11 CAR26960.1 - 0.14 12.3 0.2 0.14 12.3 0.2 1.7 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Autophagy_N PF03986.13 CAR26961.1 - 3.8e-41 140.2 3.4 5.8e-41 139.6 0.5 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 CAR26961.1 - 8.2e-15 54.0 2.2 1.6e-14 53.1 2.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 CAR26961.1 - 2.1e-13 50.6 0.5 4.9e-13 49.4 0.2 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain XPA_C PF05181.12 CAR26962.1 - 1.9e-21 75.8 1.8 8.9e-21 73.6 0.2 2.5 2 0 0 2 2 2 1 XPA protein C-terminus SAPS PF04499.15 CAR26962.1 - 0.045 12.5 3.8 0.081 11.7 3.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3027 PF11228.8 CAR26962.1 - 0.15 12.1 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) XPA_N PF01286.18 CAR26962.1 - 0.39 10.8 3.7 0.61 10.2 0.3 2.5 2 0 0 2 2 2 0 XPA protein N-terminal Glycophorin_A PF01102.18 CAR26962.1 - 1.1 9.5 3.9 0.62 10.3 0.6 2.1 2 0 0 2 2 2 0 Glycophorin A VHS PF00790.19 CAR26963.1 - 6.7e-37 126.5 0.4 5.9e-36 123.4 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 CAR26963.1 - 1.3e-18 66.9 2.8 1.3e-18 66.9 2.8 2.0 2 0 0 2 2 2 1 FYVE zinc finger UIM PF02809.20 CAR26963.1 - 1.9e-05 24.3 11.7 0.00014 21.6 1.2 4.4 4 0 0 4 4 4 2 Ubiquitin interaction motif DUF4659 PF15558.6 CAR26963.1 - 0.029 13.3 20.9 0.39 9.5 11.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4659) zf-AN1 PF01428.16 CAR26963.1 - 0.64 10.2 13.6 0.051 13.8 8.0 2.1 2 0 0 2 2 2 0 AN1-like Zinc finger Rot1 PF10681.9 CAR26964.1 - 3.5e-94 314.2 0.1 4.1e-94 314.0 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF5553 PF17707.1 CAR26964.1 - 0.088 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5553) Cyclin_N PF00134.23 CAR26965.1 - 2.2e-41 140.5 0.2 5.6e-41 139.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain RXT2_N PF08595.11 CAR26965.1 - 1.6 8.8 7.1 0.49 10.4 1.8 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal DsbG_N PF18257.1 CAR26966.1 - 0.037 14.2 0.0 11 6.2 0.1 2.5 1 1 1 2 2 2 0 Disulfide isomerase DsbG N-terminal BBP1_C PF15272.6 CAR26967.1 - 4.1e-64 215.9 24.8 4.1e-64 215.9 24.8 1.6 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal BBP1_N PF15271.6 CAR26967.1 - 7.8e-49 166.4 0.4 7.8e-49 166.4 0.4 2.3 2 1 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein DUF4515 PF14988.6 CAR26967.1 - 0.0055 16.6 22.2 0.073 12.9 5.9 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4515) CENP-H PF05837.12 CAR26967.1 - 0.0068 16.8 13.3 0.26 11.7 1.4 2.2 2 0 0 2 2 2 2 Centromere protein H (CENP-H) Pox_A_type_inc PF04508.12 CAR26967.1 - 0.11 12.4 1.2 9.1 6.3 0.1 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat zf-DBF PF07535.12 CAR26967.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger Taxilin PF09728.9 CAR26967.1 - 0.42 9.7 17.5 20 4.3 18.1 2.9 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DUF4407 PF14362.6 CAR26967.1 - 1.1 8.5 5.7 1.7 7.9 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S46 PF10459.9 CAR26967.1 - 1.8 7.1 9.2 2.3 6.8 9.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Syntaxin-6_N PF09177.11 CAR26967.1 - 1.9 9.1 8.2 1.2 9.7 4.9 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal APG6_N PF17675.1 CAR26967.1 - 7.5 7.1 21.9 7.5 7.1 4.0 2.8 1 1 1 2 2 2 0 Apg6 coiled-coil region SAGA-Tad1 PF12767.7 CAR26968.1 - 2.6e-72 243.3 0.0 1.2e-71 241.2 0.0 2.0 1 1 1 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 CAR26968.1 - 0.00094 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Microtub_bd PF16796.5 CAR26969.1 - 6.7e-26 91.0 0.2 6.7e-26 91.0 0.2 2.6 2 1 1 3 3 3 1 Microtubule binding Baculo_PEP_C PF04513.12 CAR26969.1 - 9.8 6.2 7.1 5.5 7.0 0.9 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fer2 PF00111.27 CAR26970.1 - 1.6e-14 53.6 0.4 2.3e-14 53.1 0.4 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain GalBD_like PF17974.1 CAR26970.1 - 0.14 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Galactose-binding domain-like LysM PF01476.20 CAR26970.1 - 0.19 11.8 0.0 0.55 10.3 0.0 1.8 2 0 0 2 2 2 0 LysM domain V-SNARE PF05008.15 CAR26971.1 - 6.2e-21 74.6 7.2 9.5e-21 74.0 4.8 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 CAR26971.1 - 1.6e-19 69.9 2.3 1.6e-19 69.9 2.3 2.8 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CAR26971.1 - 0.0031 17.4 0.2 0.0031 17.4 0.2 2.2 3 0 0 3 3 3 1 Sec20 Use1 PF09753.9 CAR26971.1 - 0.0045 16.8 5.4 0.011 15.5 5.4 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 TCTP PF00838.17 CAR26971.1 - 0.05 13.9 0.0 0.077 13.3 0.0 1.3 1 0 0 1 1 1 0 Translationally controlled tumour protein Baculo_p24 PF05073.12 CAR26971.1 - 0.11 12.3 5.5 0.048 13.4 0.9 2.0 1 1 1 2 2 2 0 Baculovirus P24 capsid protein Prominin PF05478.11 CAR26971.1 - 0.37 8.7 5.7 0.62 7.9 5.7 1.3 1 1 0 1 1 1 0 Prominin YqjK PF13997.6 CAR26971.1 - 0.4 11.0 0.0 0.4 11.0 0.0 2.6 3 0 0 3 3 3 0 YqjK-like protein Nsp1_C PF05064.13 CAR26971.1 - 0.9 9.4 6.2 0.15 11.9 1.7 2.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region DUF883 PF05957.13 CAR26971.1 - 4.1 8.1 5.5 24 5.6 0.4 3.0 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Glyco_hydro_63 PF03200.16 CAR26972.1 - 7.6e-07 28.3 5.9 0.00031 19.7 0.2 4.1 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain DCR PF14047.6 CAR26973.1 - 0.017 15.3 0.1 0.024 14.8 0.1 1.2 1 0 0 1 1 1 0 Dppa2/4 conserved region MTCP1 PF08991.10 CAR26976.1 - 1.7e-26 92.2 11.7 2e-26 92.0 11.7 1.0 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Cmc1 PF08583.10 CAR26976.1 - 0.11 12.5 1.5 0.11 12.5 1.5 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like FANCF PF11107.8 CAR26977.1 - 0.0079 15.4 1.9 0.0097 15.2 1.9 1.0 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) Bul1_N PF04425.12 CAR26978.1 - 1.6e-88 297.4 4.8 6.1e-86 289.0 0.1 2.5 2 1 1 3 3 3 2 Bul1 N terminus Bul1_C PF04426.12 CAR26978.1 - 4e-25 88.8 0.2 1.8e-11 44.0 0.0 2.8 1 1 1 2 2 2 2 Bul1 C terminus Arrestin_C PF02752.22 CAR26978.1 - 0.0075 16.7 0.0 4.2 7.8 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CAR26978.1 - 0.065 13.3 0.5 1.4 9.0 0.1 2.7 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 CAR26979.1 - 3.1e-90 303.1 2.6 5.6e-87 292.4 0.3 2.1 1 1 1 2 2 2 2 Bul1 N terminus Bul1_C PF04426.12 CAR26979.1 - 4.5e-06 26.3 0.0 9.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Bul1 C terminus Ribosomal_L36e PF01158.18 CAR26980.1 - 1.4e-35 121.4 1.7 1.6e-35 121.2 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Ribosomal_L28 PF00830.19 CAR26981.1 - 3.9e-17 62.2 0.3 9e-17 61.0 0.3 1.6 1 0 0 1 1 1 1 Ribosomal L28 family CDP-OH_P_transf PF01066.21 CAR26982.1 - 2.6e-11 44.1 0.4 2.6e-11 44.1 0.4 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_S10 PF00450.22 CAR26983.1 - 1.4e-102 344.2 0.1 1.8e-102 343.9 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase CDC45 PF02724.14 CAR26983.1 - 0.0025 16.2 5.3 0.0034 15.7 5.3 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF4366 PF14283.6 CAR26983.1 - 0.045 13.8 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Presenilin PF01080.17 CAR26983.1 - 0.24 10.1 1.3 0.37 9.5 1.3 1.2 1 0 0 1 1 1 0 Presenilin Aminotran_1_2 PF00155.21 CAR26984.1 - 5.6e-27 94.9 0.0 7e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CAR26984.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Phosphorylase PF00343.20 CAR26985.1 - 0 1012.4 0.0 0 1012.1 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Inj_translocase PF16928.5 CAR26985.1 - 0.031 13.7 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Mrr_cat_2 PF13156.6 CAR26985.1 - 0.071 13.0 0.1 0.31 10.9 0.1 2.1 1 0 0 1 1 1 0 Restriction endonuclease MCM PF00493.23 CAR26986.1 - 8.7e-102 339.0 0.3 1.4e-101 338.3 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR26986.1 - 4e-39 133.3 0.1 2.5e-38 130.7 0.1 2.3 2 0 0 2 2 2 1 MCM OB domain MCM6_C PF18263.1 CAR26986.1 - 3.5e-31 107.6 0.5 3.5e-31 107.6 0.5 2.3 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 CAR26986.1 - 6e-26 90.7 0.6 1.3e-25 89.6 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CAR26986.1 - 9.9e-26 90.4 2.3 3e-25 88.8 0.1 2.7 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAR26986.1 - 4e-07 29.6 0.0 1.2e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI GIDA_assoc PF13932.6 CAR26986.1 - 0.0023 18.1 1.3 0.0023 18.1 1.3 2.0 2 0 0 2 2 2 1 GidA associated domain Sigma54_activat PF00158.26 CAR26986.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 CAR26986.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAR26986.1 - 0.037 14.0 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RRN3 PF05327.11 CAR26986.1 - 0.22 10.0 3.6 0.43 9.1 3.6 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BBP1_N PF15271.6 CAR26986.1 - 0.39 11.5 5.5 0.47 11.2 0.7 2.9 2 1 0 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein Cyclin_N PF00134.23 CAR26987.1 - 2.6e-38 130.6 0.1 2.6e-38 130.6 0.1 2.8 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAR26987.1 - 7.5e-34 116.4 2.3 2.8e-33 114.5 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain Pex14_N PF04695.13 CAR26987.1 - 0.06 14.0 11.6 0.13 13.0 11.6 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 CAR26987.1 - 0.19 10.4 12.3 0.31 9.8 12.3 1.3 1 0 0 1 1 1 0 Presenilin Androgen_recep PF02166.16 CAR26987.1 - 0.25 10.1 11.5 0.35 9.6 11.5 1.1 1 0 0 1 1 1 0 Androgen receptor Endostatin PF06482.11 CAR26987.1 - 0.27 10.6 8.1 0.39 10.1 8.1 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Ndc1_Nup PF09531.10 CAR26987.1 - 0.44 9.2 7.3 0.56 8.8 7.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 CAR26987.1 - 0.98 9.4 5.3 1.5 8.8 5.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PA26 PF04636.13 CAR26987.1 - 1.5 7.7 12.1 7.5 5.3 12.7 1.8 2 1 0 2 2 2 0 PA26 p53-induced protein (sestrin) MID_MedPIWI PF18296.1 CAR26987.1 - 1.6 8.5 12.8 3.5 7.4 12.8 1.5 1 0 0 1 1 1 0 MID domain of medPIWI Suf PF05843.14 CAR26987.1 - 2.2 8.2 12.6 3.6 7.5 12.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TetR_C_29 PF17938.1 CAR26987.1 - 2.9 8.0 6.0 3 8.0 0.2 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Roughex PF06020.11 CAR26987.1 - 4.9 6.2 14.1 1.9 7.5 11.6 1.5 2 0 0 2 2 2 0 Drosophila roughex protein Zip PF02535.22 CAR26987.1 - 6.2 5.9 7.4 9.3 5.4 7.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Cyclin_N PF00134.23 CAR26988.1 - 1.2e-40 138.2 4.4 1.5e-40 137.9 0.3 2.7 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAR26988.1 - 4.8e-19 68.6 0.1 1.4e-18 67.1 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Abhydrolase_1 PF00561.20 CAR26991.1 - 3.3e-19 69.6 0.4 4.3e-19 69.2 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR26991.1 - 4.7e-12 47.0 0.0 7.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR26991.1 - 1.2e-08 34.5 0.0 1.4e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CAR26991.1 - 0.0033 16.9 0.1 0.97 8.9 0.0 3.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 CAR26991.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase CCSMST1 PF15013.6 CAR26992.1 - 0.042 14.0 0.1 0.077 13.2 0.1 1.3 1 0 0 1 1 1 0 CCSMST1 family PsbT PF01405.17 CAR26992.1 - 0.5 10.2 2.4 0.92 9.4 2.4 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Peptidase_M16 PF00675.20 CAR26993.1 - 3e-33 114.9 0.1 8.9e-33 113.4 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 CAR26993.1 - 1.3e-12 47.7 0.4 2.9e-12 46.5 0.4 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CAR26993.1 - 1.1e-08 35.4 1.3 0.0028 17.7 0.0 4.7 5 1 0 5 5 5 2 Peptidase M16 inactive domain DUF3135 PF11333.8 CAR26993.1 - 0.11 12.8 0.2 0.39 11.0 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Acetyltransf_7 PF13508.7 CAR26994.1 - 8e-06 26.2 0.0 1.7e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CAR26994.1 - 0.00042 20.4 0.2 0.0022 18.0 0.2 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 CAR26994.1 - 0.016 15.3 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAR26994.1 - 0.019 15.2 0.0 0.048 13.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 CAR26994.1 - 0.021 14.9 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TLD PF07534.16 CAR26994.1 - 0.058 13.6 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 TLD Acetyltransf_3 PF13302.7 CAR26994.1 - 0.13 12.9 0.0 0.43 11.3 0.0 2.0 2 2 0 2 2 2 0 Acetyltransferase (GNAT) domain SURF1 PF02104.15 CAR26995.1 - 2.7e-43 148.3 1.0 3.9e-43 147.7 1.0 1.2 1 0 0 1 1 1 1 SURF1 family ig PF00047.25 CAR26995.1 - 0.0058 16.8 1.5 0.016 15.4 0.4 2.3 2 1 1 3 3 3 1 Immunoglobulin domain DUF5634 PF18681.1 CAR26995.1 - 0.04 14.3 0.0 0.098 13.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5634) DASH_Dam1 PF08653.10 CAR26996.1 - 9.4e-25 86.2 0.2 1.9e-24 85.2 0.2 1.5 1 0 0 1 1 1 1 DASH complex subunit Dam1 Ctr PF04145.15 CAR26997.1 - 2.2e-22 80.3 3.3 2.2e-22 80.3 3.3 1.9 2 0 0 2 2 2 1 Ctr copper transporter family SH2_2 PF14633.6 CAR26998.1 - 3.2e-69 232.6 3.1 3.2e-69 232.6 3.1 1.9 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 CAR26998.1 - 2.9e-64 215.4 0.0 8.8e-64 213.8 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 CAR26998.1 - 6.3e-45 151.8 0.0 1.9e-44 150.2 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 CAR26998.1 - 5.3e-36 123.5 1.9 1.8e-35 121.9 1.9 2.0 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 CAR26998.1 - 9.7e-19 67.8 16.8 9.7e-19 67.8 16.8 6.1 3 1 3 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.24 CAR26998.1 - 3.2e-12 46.4 0.1 1e-11 44.8 0.1 1.9 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 CAR26998.1 - 1.6e-05 25.7 0.6 0.00022 22.1 0.6 3.2 1 1 0 1 1 1 1 HHH domain Aldo_ket_red PF00248.21 CAR26999.1 - 2.3e-45 155.0 0.0 2.9e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YjcQ PF09639.10 CAR26999.1 - 0.095 12.9 0.0 5.4 7.3 0.0 2.4 2 0 0 2 2 2 0 YjcQ protein Mito_carr PF00153.27 CAR27000.1 - 1.5e-56 188.3 4.7 4.7e-20 71.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MBD PF01429.19 CAR27000.1 - 0.009 15.7 0.0 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 Methyl-CpG binding domain DUF2700 PF10912.8 CAR27000.1 - 0.06 13.4 0.3 0.46 10.5 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2700) TRAPP PF04051.16 CAR27002.1 - 9.3e-48 161.7 0.0 1.2e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component GP3 PF03076.14 CAR27002.1 - 0.0013 18.9 0.1 0.002 18.2 0.1 1.3 1 0 0 1 1 1 1 Equine arteritis virus GP3 Acetyltransf_1 PF00583.25 CAR27003.1 - 6.4e-13 49.0 0.0 9.1e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR27003.1 - 1.3e-07 31.6 0.1 2e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAR27003.1 - 7.3e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CAR27003.1 - 8.7e-05 22.9 0.0 0.00014 22.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CAR27003.1 - 0.0018 18.3 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TcA_TcB_BD PF18276.1 CAR27003.1 - 0.014 14.5 0.3 0.019 14.1 0.3 1.1 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain Acetyltransf_15 PF17013.5 CAR27003.1 - 0.025 14.1 0.1 0.033 13.6 0.1 1.5 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 CAR27003.1 - 0.073 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Metallophos_2 PF12850.7 CAR27004.1 - 1.6e-09 38.2 0.0 3.7e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Neur_chan_memb PF02932.16 CAR27004.1 - 0.038 14.1 1.9 0.042 13.9 1.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SID-1_RNA_chan PF13965.6 CAR27004.1 - 0.043 12.2 1.5 0.056 11.8 1.5 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM60A PF15396.6 CAR27004.1 - 0.19 11.7 6.4 0.26 11.2 6.4 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MCM_bind PF09739.9 CAR27004.1 - 0.52 8.7 11.0 0.67 8.3 11.0 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Kei1 PF08552.11 CAR27004.1 - 0.6 10.0 5.4 1 9.2 5.4 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 MAJIN PF15077.6 CAR27004.1 - 0.96 9.2 6.1 1.4 8.7 6.1 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein SAPS PF04499.15 CAR27004.1 - 0.99 8.1 16.2 1.3 7.7 16.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 CAR27004.1 - 3.1 6.5 20.4 4.2 6.0 20.4 1.1 1 0 0 1 1 1 0 Presenilin Membralin PF09746.9 CAR27004.1 - 6.8 5.6 8.0 28 3.6 7.3 1.9 2 0 0 2 2 2 0 Tumour-associated protein Zip PF02535.22 CAR27004.1 - 7 5.8 15.5 9.8 5.3 15.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter tRNA-synt_2b PF00587.25 CAR27005.1 - 4.8e-24 85.3 0.0 8.1e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CAR27005.1 - 3e-05 24.2 6.9 3e-05 24.2 6.9 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 CAR27005.1 - 0.00033 19.8 2.2 0.00048 19.3 2.2 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 CREPT PF16566.5 CAR27005.1 - 0.00059 20.0 5.3 0.0011 19.2 5.3 1.4 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Syntaxin PF00804.25 CAR27005.1 - 0.028 14.1 2.4 0.047 13.4 2.4 1.3 1 0 0 1 1 1 0 Syntaxin Poty_PP PF08440.10 CAR27005.1 - 0.031 13.4 1.6 0.049 12.7 1.6 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein ATG16 PF08614.11 CAR27005.1 - 0.046 13.9 6.9 0.087 13.0 6.9 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 CAR27005.1 - 0.089 12.9 8.6 0.38 10.8 8.7 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4404 PF14357.6 CAR27005.1 - 0.12 13.0 5.6 0.24 12.1 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) KASH_CCD PF14662.6 CAR27005.1 - 0.12 12.2 10.7 0.22 11.3 9.9 1.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH TMPIT PF07851.13 CAR27005.1 - 0.28 10.4 3.2 0.42 9.8 3.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Baculo_PEP_C PF04513.12 CAR27005.1 - 0.32 11.0 2.9 0.66 10.0 2.9 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 CAR27005.1 - 0.32 9.8 7.1 0.52 9.1 7.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein COG5 PF10392.9 CAR27005.1 - 0.43 10.7 6.8 0.4 10.9 0.9 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF29 PF01724.16 CAR27005.1 - 0.74 10.0 5.4 7.3 6.8 2.8 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF29 FapA PF03961.13 CAR27005.1 - 1.6 7.2 5.5 2.5 6.6 5.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Med9 PF07544.13 CAR27005.1 - 5.2 7.2 11.8 4.7 7.4 7.0 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Ribosomal_L27e PF01777.18 CAR27006.1 - 3.6e-37 126.6 6.3 5.3e-37 126.0 6.3 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CAR27006.1 - 0.00075 19.4 1.9 0.0015 18.4 1.9 1.6 1 0 0 1 1 1 1 KOW motif MPS2 PF17060.5 CAR27007.1 - 1.4e-05 24.5 8.5 1.8e-05 24.2 8.5 1.3 1 0 0 1 1 1 1 Monopolar spindle protein 2 MutS_III PF05192.18 CAR27007.1 - 0.0028 17.9 5.8 0.0035 17.6 5.8 1.3 1 0 0 1 1 1 1 MutS domain III Seryl_tRNA_N PF02403.22 CAR27007.1 - 0.0097 16.1 13.0 0.51 10.6 7.7 2.4 1 1 1 2 2 2 2 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 CAR27007.1 - 0.01 16.1 20.6 0.018 15.3 20.6 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PDDEXK_1 PF12705.7 CAR27007.1 - 0.025 14.5 2.2 0.035 14.0 2.2 1.2 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily AAA_23 PF13476.6 CAR27007.1 - 0.057 13.9 11.9 0.093 13.2 11.9 1.3 1 0 0 1 1 1 0 AAA domain FliD_N PF02465.18 CAR27007.1 - 0.067 13.9 0.7 0.067 13.9 0.7 3.1 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DHR10 PF18595.1 CAR27007.1 - 0.12 12.4 25.6 0.91 9.6 22.4 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain SpecificRecomb PF10136.9 CAR27007.1 - 0.15 10.3 8.3 0.14 10.4 7.3 1.4 1 1 0 1 1 1 0 Site-specific recombinase FUSC PF04632.12 CAR27007.1 - 0.2 10.2 5.5 0.24 9.9 5.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family GAS PF13851.6 CAR27007.1 - 0.27 10.6 25.8 0.87 8.9 20.3 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ADIP PF11559.8 CAR27007.1 - 0.54 10.3 20.8 13 5.8 20.5 2.4 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding RmuC PF02646.16 CAR27007.1 - 0.8 8.8 16.0 0.18 10.9 0.5 2.7 1 1 2 3 3 3 0 RmuC family Tropomyosin_1 PF12718.7 CAR27007.1 - 0.87 9.7 21.2 1.1 9.4 19.5 2.0 1 1 1 2 2 2 0 Tropomyosin like Occludin_ELL PF07303.13 CAR27007.1 - 0.91 10.3 15.0 0.99 10.2 10.3 2.7 1 1 2 3 3 3 0 Occludin homology domain DASH_Dam1 PF08653.10 CAR27007.1 - 1 9.2 7.7 3.3 7.6 0.0 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF948 PF06103.11 CAR27007.1 - 1.2 9.4 7.9 0.87 9.9 4.4 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF465 PF04325.13 CAR27007.1 - 1.5 9.0 13.4 0.94 9.6 0.2 3.2 3 1 0 3 3 2 0 Protein of unknown function (DUF465) DUF16 PF01519.16 CAR27007.1 - 1.5 9.4 16.5 1.5 9.3 11.5 2.7 1 1 0 2 2 2 0 Protein of unknown function DUF16 DUF724 PF05266.14 CAR27007.1 - 1.7 8.5 15.4 3.8 7.3 14.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Mod_r PF07200.13 CAR27007.1 - 1.8 8.6 22.1 1.4 9.1 5.7 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein TMF_TATA_bd PF12325.8 CAR27007.1 - 3 8.1 22.0 7.4 6.8 14.7 2.7 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 CAR27007.1 - 3.1 6.6 20.2 4.7 6.0 19.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3450 PF11932.8 CAR27007.1 - 3.4 6.9 20.6 2.2 7.5 15.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SlyX PF04102.12 CAR27007.1 - 3.4 8.3 19.8 4.2 8.0 2.4 3.9 1 1 3 4 4 4 0 SlyX dCache_2 PF08269.11 CAR27007.1 - 5.2 6.1 9.9 2.5 7.2 7.3 1.7 1 1 1 2 2 2 0 Cache domain FapA PF03961.13 CAR27007.1 - 5.6 5.4 12.1 4.5 5.8 6.7 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A APG6_N PF17675.1 CAR27007.1 - 5.8 7.5 23.4 82 3.7 23.4 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region Allexi_40kDa PF05549.11 CAR27007.1 - 7.6 6.0 11.8 5 6.6 6.6 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein EMP24_GP25L PF01105.24 CAR27007.1 - 7.7 6.4 12.1 6 6.8 6.8 2.7 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD BLOC1_2 PF10046.9 CAR27007.1 - 7.7 6.9 17.2 2.8 8.3 7.9 3.2 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 CAR27007.1 - 8.6 6.4 12.3 9.7 6.2 6.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CAR27007.1 - 9 5.6 13.6 18 4.6 12.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Mito_carr PF00153.27 CAR27008.1 - 1.1e-11 44.5 0.0 0.00039 20.3 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Dpy-30 PF05186.13 CAR27009.1 - 6.5e-17 60.9 0.0 9e-17 60.5 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif SNARE PF05739.19 CAR27010.1 - 5.2e-07 29.6 0.5 5.2e-07 29.6 0.5 2.6 2 0 0 2 2 2 1 SNARE domain HisKA_3 PF07730.13 CAR27010.1 - 0.0099 16.4 1.6 0.13 12.8 0.2 2.6 2 1 0 2 2 2 1 Histidine kinase LPD29 PF18847.1 CAR27010.1 - 0.01 16.8 0.3 0.042 14.8 0.1 1.9 1 1 1 2 2 2 0 Large polyvalent protein associated domain 29 PhoU_div PF01865.16 CAR27010.1 - 0.016 14.5 7.4 0.1 11.9 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF47 L1R_F9L PF02442.17 CAR27010.1 - 0.022 14.6 0.8 0.78 9.6 0.8 2.2 1 1 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Syntaxin-6_N PF09177.11 CAR27010.1 - 0.032 14.8 4.7 0.032 14.8 4.7 3.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2207 PF09972.9 CAR27010.1 - 0.057 12.2 2.9 0.21 10.3 0.0 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MPS2 PF17060.5 CAR27010.1 - 0.077 12.2 6.2 0.024 13.9 2.4 1.8 1 1 1 2 2 2 0 Monopolar spindle protein 2 DUF745 PF05335.13 CAR27010.1 - 0.079 12.7 7.1 1.3 8.7 1.6 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Baculo_PEP_C PF04513.12 CAR27010.1 - 0.092 12.8 8.7 1.4 9.0 2.8 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 CAR27010.1 - 0.093 13.2 8.7 0.24 11.9 0.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mt_ATP-synt_D PF05873.12 CAR27010.1 - 0.2 11.5 5.4 3.7 7.4 0.7 2.4 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1664 PF07889.12 CAR27010.1 - 0.28 11.2 10.1 0.6 10.2 0.6 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 CAR27010.1 - 0.34 11.4 12.0 1.1 9.8 1.1 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 Prefoldin_2 PF01920.20 CAR27010.1 - 0.37 10.8 8.7 0.22 11.5 1.3 2.9 3 1 0 3 3 3 0 Prefoldin subunit Interferon PF00143.19 CAR27010.1 - 0.51 10.5 7.5 0.11 12.7 0.4 2.2 1 1 0 2 2 2 0 Interferon alpha/beta domain SKA1 PF07160.12 CAR27010.1 - 0.61 9.9 10.0 1.5 8.6 0.4 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 HSBP1 PF06825.12 CAR27010.1 - 0.64 9.9 8.6 1.6 8.7 1.2 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Sec20 PF03908.13 CAR27010.1 - 0.84 9.6 4.7 0.71 9.8 0.2 2.3 2 1 0 2 2 2 0 Sec20 V-SNARE_C PF12352.8 CAR27010.1 - 1.3 9.3 7.3 0.65 10.3 2.7 2.7 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus BST2 PF16716.5 CAR27010.1 - 2 9.0 10.5 0.72 10.5 0.6 2.9 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 WXG100 PF06013.12 CAR27010.1 - 3 8.2 7.9 28 5.0 0.3 3.3 2 2 0 2 2 2 0 Proteins of 100 residues with WXG MCU PF04678.13 CAR27010.1 - 4.3 7.4 6.2 2.5 8.2 1.1 2.1 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Fzo_mitofusin PF04799.13 CAR27010.1 - 4.3 6.9 8.6 0.93 9.0 1.6 2.3 1 1 2 3 3 3 0 fzo-like conserved region V_ATPase_I PF01496.19 CAR27010.1 - 5.4 4.8 11.4 5.3 4.8 9.7 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 CAR27010.1 - 7.2 7.3 10.0 12 6.6 1.0 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DAO PF01266.24 CAR27011.1 - 7.8e-80 269.1 0.0 9.8e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAR27011.1 - 1.6e-06 28.2 0.0 6.7e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CAR27011.1 - 0.00022 20.6 0.1 0.00041 19.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 CAR27011.1 - 0.00042 19.3 0.0 0.0005 19.0 0.0 1.2 1 0 0 1 1 1 1 MCRA family Pyr_redox_2 PF07992.14 CAR27011.1 - 0.00042 19.7 1.2 0.071 12.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 CAR27011.1 - 0.017 15.4 0.0 0.057 13.7 0.1 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 CAR27011.1 - 0.019 15.0 0.2 0.09 12.8 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 CAR27011.1 - 0.045 12.6 0.0 0.17 10.7 0.1 1.8 2 0 0 2 2 2 0 Tryptophan halogenase Cwf_Cwc_15 PF04889.12 CAR27011.1 - 0.1 12.3 11.0 0.15 11.8 11.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pyr_redox PF00070.27 CAR27011.1 - 0.14 12.7 0.0 0.32 11.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Spem1 PF15670.5 CAR27011.1 - 0.37 10.3 5.5 0.091 12.3 2.1 1.6 2 0 0 2 2 2 0 Spermatid maturation protein 1 Pkinase PF00069.25 CAR27012.1 - 6.8e-63 212.5 0.0 9.9e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27012.1 - 4e-33 114.8 0.0 6.1e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR27012.1 - 7.5e-08 32.0 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR27012.1 - 0.00036 20.5 0.2 0.0012 18.8 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAR27012.1 - 0.0022 16.8 3.6 0.01 14.6 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 CAR27012.1 - 0.007 16.0 0.0 0.02 14.5 0.0 1.7 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 CAR27012.1 - 0.023 14.0 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Menin PF05053.13 CAR27012.1 - 0.65 8.3 5.3 0.92 7.8 5.3 1.1 1 0 0 1 1 1 0 Menin Sod_Fe_C PF02777.18 CAR27013.1 - 1.2e-33 115.3 0.7 1.2e-33 115.3 0.7 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CAR27013.1 - 5e-26 91.0 0.5 1e-25 90.0 0.5 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Methyltransf_11 PF08241.12 CAR27014.1 - 0.0087 16.7 0.0 0.033 14.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR27014.1 - 0.097 13.4 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain NUDIX PF00293.28 CAR27016.1 - 1.1e-16 61.1 0.1 1.3e-16 60.9 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain DUF410 PF04190.13 CAR27017.1 - 9e-80 268.1 2.8 1.1e-79 267.9 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) FWWh PF14922.6 CAR27017.1 - 0.11 12.4 2.6 1.1 9.2 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function RHD3 PF05879.12 CAR27018.1 - 8.2e-241 801.2 15.5 1e-240 800.9 15.5 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.23 CAR27018.1 - 2.8e-05 24.2 0.5 0.00015 21.9 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CAR27018.1 - 9.9e-05 22.4 0.0 0.00034 20.7 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF5387 PF17361.2 CAR27018.1 - 0.019 14.7 0.2 0.4 10.3 0.0 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5387) AAA_28 PF13521.6 CAR27018.1 - 0.054 13.7 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CAR27018.1 - 0.067 13.4 0.1 0.21 11.8 0.1 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase YbfN PF13982.6 CAR27018.1 - 0.11 12.8 2.6 0.32 11.3 0.1 2.9 3 0 0 3 3 3 0 YbfN-like lipoprotein Phasin PF05597.11 CAR27018.1 - 0.11 12.5 2.4 0.4 10.7 0.4 2.9 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Nbl1_Borealin_N PF10444.9 CAR27018.1 - 1.1 8.9 5.4 0.57 9.9 0.2 2.8 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF445 PF04286.12 CAR27018.1 - 7.3 6.3 10.3 23 4.6 10.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF445) XLF PF09302.11 CAR27019.1 - 0.036 14.2 0.2 0.089 13.0 0.1 1.8 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component PIN_4 PF13638.6 CAR27020.1 - 5.2e-31 107.6 0.1 1.1e-30 106.6 0.1 1.6 1 0 0 1 1 1 1 PIN domain PIN_9 PF18477.1 CAR27020.1 - 0.027 14.8 0.1 1.1 9.5 0.1 2.5 1 1 0 1 1 1 0 PIN like domain Red1 PF07964.11 CAR27021.1 - 3.4e-156 521.6 50.1 6.6e-81 272.7 48.0 2.7 1 1 1 2 2 2 2 Rec10 / Red1 tRNA-synt_1c PF00749.21 CAR27022.1 - 1.9e-115 385.1 0.0 2.9e-115 384.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 CAR27022.1 - 1.5e-50 171.4 2.9 2.4e-50 170.7 2.9 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 CAR27022.1 - 2.3e-30 105.8 0.1 4.4e-29 101.6 0.0 2.4 1 1 1 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 CAR27022.1 - 6.4e-12 46.2 3.2 6.4e-12 46.2 3.2 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Peptidase_M26_C PF07580.14 CAR27022.1 - 0.031 12.8 0.5 0.047 12.2 0.5 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region TMA7 PF09072.10 CAR27023.1 - 4.3e-20 72.3 21.2 4.7e-20 72.2 21.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Ras PF00071.22 CAR27024.1 - 1.8e-57 193.5 0.4 2.2e-57 193.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR27024.1 - 8.7e-38 129.2 0.1 1.5e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR27024.1 - 3.6e-16 59.1 0.2 4.3e-16 58.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR27024.1 - 1.8e-05 24.8 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR27024.1 - 1.9e-05 24.6 0.1 0.075 12.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CAR27024.1 - 2.7e-05 23.7 0.0 5.7e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CAR27024.1 - 0.00018 21.0 0.2 0.00023 20.6 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR27024.1 - 0.00037 20.1 0.1 0.0037 16.8 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CAR27024.1 - 0.0026 17.5 0.7 0.02 14.6 0.7 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CAR27024.1 - 0.0053 16.3 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase_2 PF01637.18 CAR27024.1 - 0.0081 16.1 0.5 0.03 14.2 0.0 1.8 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CAR27024.1 - 0.014 15.1 0.2 0.022 14.5 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CAR27024.1 - 0.03 14.7 0.0 0.047 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CAR27024.1 - 0.032 14.5 0.0 0.073 13.3 0.0 1.6 1 1 0 2 2 2 0 AAA domain DLIC PF05783.11 CAR27024.1 - 0.04 12.7 0.1 0.081 11.7 0.0 1.5 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) ResIII PF04851.15 CAR27024.1 - 0.07 13.1 0.1 0.12 12.3 0.1 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CAR27024.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_15 PF13175.6 CAR27024.1 - 0.21 11.2 6.9 4.7 6.8 2.7 2.0 1 1 0 2 2 2 0 AAA ATPase domain DAGK_cat PF00781.24 CAR27025.1 - 7.5e-26 90.2 0.0 1.2e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Mgr1 PF08602.10 CAR27025.1 - 0.035 12.9 0.1 0.059 12.2 0.1 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Herpes_LMP1 PF05297.11 CAR27025.1 - 0.99 8.5 3.9 1.4 8.0 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Cpn60_TCP1 PF00118.24 CAR27026.1 - 4.9e-82 276.1 11.9 8.8e-82 275.3 11.9 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Deltameth_res PF16020.5 CAR27026.1 - 0.19 11.6 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Deltamethrin resistance GIT_CC PF16559.5 CAR27027.1 - 4.6 7.2 26.3 0.17 11.8 0.5 5.0 4 2 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor RNA_pol_I_TF PF04090.12 CAR27028.1 - 1.4e-70 236.8 0.1 2.3e-70 236.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor zf-rbx1 PF12678.7 CAR27029.1 - 1.9e-07 31.3 3.9 4.5e-07 30.1 3.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CAR27029.1 - 1.1e-06 28.4 2.4 3.9e-06 26.6 2.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR27029.1 - 1.9e-05 24.9 14.8 3.2e-05 24.2 11.7 2.5 2 1 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 CAR27029.1 - 4.4e-05 23.3 3.6 9.4e-05 22.3 3.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CAR27029.1 - 0.00013 21.8 2.8 0.00013 21.8 2.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR27029.1 - 0.00019 21.4 2.5 0.00053 20.0 2.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CAR27029.1 - 0.00036 20.3 0.5 0.00036 20.3 0.5 1.7 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CAR27029.1 - 0.00037 20.3 1.1 0.00037 20.3 1.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF4457 PF14652.6 CAR27029.1 - 0.0069 15.7 0.0 0.074 12.3 0.0 2.0 1 1 0 2 2 2 1 Domain of unknown function (DUF4457) Zn_ribbon_17 PF17120.5 CAR27029.1 - 0.0095 15.5 0.3 0.0095 15.5 0.3 1.8 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 CAR27029.1 - 0.016 15.4 5.5 0.29 11.3 1.3 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 CAR27029.1 - 0.024 14.0 0.2 0.042 13.2 0.2 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger zf-ANAPC11 PF12861.7 CAR27029.1 - 0.026 14.6 0.5 0.026 14.6 0.5 1.6 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Dicty_REP PF05086.12 CAR27029.1 - 0.092 10.7 13.3 0.041 11.9 9.9 1.9 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein zf-P11 PF03854.14 CAR27029.1 - 0.21 11.3 1.9 0.64 9.7 1.9 1.8 1 0 0 1 1 1 0 P-11 zinc finger Mucin PF01456.17 CAR27029.1 - 0.41 10.6 31.5 0.92 9.5 31.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein CTU2 PF10288.9 CAR27029.1 - 0.58 10.4 7.8 3.3 8.0 7.8 2.2 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-RING_4 PF14570.6 CAR27029.1 - 1.7 8.5 7.0 0.18 11.6 1.3 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain MGC-24 PF05283.11 CAR27029.1 - 8.9 6.8 15.8 19 5.7 15.8 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Histone PF00125.24 CAR27030.1 - 8.7e-17 61.7 0.0 1.1e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CAR27030.1 - 1e-12 47.5 0.1 1.7e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CAR27030.1 - 0.001 19.3 0.0 0.0014 18.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PLA2_B PF01735.18 CAR27031.1 - 5.2e-214 711.2 2.1 6.3e-214 710.9 2.1 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 CAR27031.1 - 0.025 14.8 2.0 0.052 13.8 2.0 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TAF4 PF05236.14 CAR27032.1 - 1.1e-59 202.5 2.4 1.1e-59 202.5 2.4 2.1 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family RTC PF01137.21 CAR27033.1 - 1.4e-45 155.2 0.0 1.6e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CAR27033.1 - 3.6e-31 107.7 0.0 5.8e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.24 CAR27034.1 - 1.7e-21 76.3 0.2 3.5e-21 75.3 0.2 1.5 1 0 0 1 1 1 1 PX domain Casc1_N PF15927.5 CAR27034.1 - 0.091 12.4 4.4 0.077 12.7 0.4 2.5 3 0 0 3 3 3 0 Cancer susceptibility candidate 1 N-terminus CCDC106 PF15794.5 CAR27034.1 - 0.47 10.1 2.2 0.78 9.4 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 MMM1 PF10296.9 CAR27035.1 - 1.6e-09 37.2 0.2 2.3e-09 36.7 0.2 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 EF-hand_2 PF09068.11 CAR27035.1 - 0.039 14.1 0.0 1.1 9.4 0.0 2.3 1 1 1 2 2 2 0 EF hand Polyketide_cyc PF03364.20 CAR27036.1 - 1.2e-16 61.1 0.1 1.5e-16 60.8 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SAP PF02037.27 CAR27037.1 - 2.8e-10 39.7 2.0 5e-10 38.9 2.0 1.4 1 0 0 1 1 1 1 SAP domain DUF2076 PF09849.9 CAR27038.1 - 8.8e-05 22.7 17.8 0.00017 21.7 17.9 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 CAR27038.1 - 0.00017 21.6 5.0 0.00026 21.0 4.3 1.7 1 1 0 1 1 1 1 CHCH domain CX9C PF16860.5 CAR27038.1 - 0.042 13.9 3.0 0.091 12.8 3.0 1.5 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX6B PF02297.17 CAR27038.1 - 0.43 10.8 5.5 0.79 10.0 5.5 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF2207 PF09972.9 CAR27039.1 - 0.04 12.7 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Topoisom_I PF01028.20 CAR27040.1 - 5.2e-96 320.4 3.6 5.2e-96 320.4 3.6 3.4 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CAR27040.1 - 1.6e-95 318.6 1.4 1.6e-95 318.6 1.4 4.1 3 2 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 CAR27040.1 - 8e-32 109.0 0.1 8e-32 109.0 0.1 2.7 2 0 0 2 2 2 1 C-terminal topoisomerase domain Mucin PF01456.17 CAR27040.1 - 4.6 7.2 18.2 8.7 6.3 18.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase PF00069.25 CAR27041.1 - 7.7e-74 248.4 0.0 1.2e-73 247.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27041.1 - 6.2e-40 137.1 0.0 8.9e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CAR27041.1 - 1.6e-27 95.5 0.0 3.9e-14 52.6 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CAR27041.1 - 2e-08 33.9 0.0 3.4e-07 29.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like SH3_3 PF08239.11 CAR27041.1 - 0.002 18.3 0.1 0.0046 17.2 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Kdo PF06293.14 CAR27041.1 - 0.0048 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAR27041.1 - 0.033 13.1 0.2 0.09 11.7 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain RNA_pol_L_2 PF13656.6 CAR27042.1 - 5.4e-25 87.0 0.0 6.8e-25 86.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CAR27042.1 - 2.4e-09 36.5 0.0 3.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sin3a_C PF16879.5 CAR27043.1 - 8.8e-80 268.5 4.0 8.8e-80 268.5 4.0 3.1 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 CAR27043.1 - 2.8e-47 158.6 9.4 8.5e-18 64.2 2.1 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CAR27043.1 - 2.1e-42 143.1 1.0 6e-42 141.7 0.2 2.3 2 0 0 2 2 2 1 Sin3 family co-repressor DHHC PF01529.20 CAR27044.1 - 2.2e-30 105.5 13.7 2.2e-30 105.5 13.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase HlyIII PF03006.20 CAR27045.1 - 2.4e-56 191.0 21.3 2.8e-56 190.7 21.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.6 CAR27045.1 - 0.12 12.9 1.9 0.28 11.7 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) Cyclin PF08613.11 CAR27046.1 - 2.2e-34 119.2 1.4 2.2e-34 119.2 1.4 1.7 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CAR27046.1 - 0.00064 19.5 0.1 0.0011 18.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DNA_pol_A_exo1 PF01612.20 CAR27047.1 - 7.7e-45 152.7 0.4 1.5e-44 151.8 0.4 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CAR27047.1 - 2.3e-24 85.9 4.9 5.9e-23 81.4 0.8 2.9 2 0 0 2 2 2 2 PMC2NT (NUC016) domain HRDC PF00570.23 CAR27047.1 - 8.8e-09 35.2 0.0 3e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 HRDC domain DUF4661 PF15576.6 CAR27047.1 - 7.8 6.3 6.0 18 5.1 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) Ras PF00071.22 CAR27048.1 - 8e-58 194.6 0.6 9.7e-58 194.3 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR27048.1 - 2e-33 115.2 0.1 3.6e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR27048.1 - 7.5e-16 58.1 0.1 8.7e-16 57.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR27048.1 - 1.5e-07 31.1 0.1 1.7e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR27048.1 - 2.7e-07 30.3 0.5 7e-06 25.7 0.5 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAR27048.1 - 1e-06 28.8 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CAR27048.1 - 3e-06 26.8 0.2 4.1e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CAR27048.1 - 5.1e-05 23.3 0.2 0.019 14.8 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 CAR27048.1 - 0.00015 21.6 0.5 0.0025 17.6 0.1 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 CAR27048.1 - 0.0032 17.8 0.0 0.0088 16.3 0.0 1.8 1 1 1 2 2 2 1 AAA domain PduV-EutP PF10662.9 CAR27048.1 - 0.0051 16.6 0.9 0.12 12.1 0.9 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CAR27048.1 - 0.0073 16.7 0.1 0.016 15.6 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 CAR27048.1 - 0.0093 15.6 0.0 0.029 14.0 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CAR27048.1 - 0.011 15.7 0.1 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 NTPase TniB PF05621.11 CAR27048.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 CAR27048.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CAR27048.1 - 0.028 13.9 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CAR27048.1 - 0.032 13.9 0.1 0.097 12.4 0.0 1.9 2 1 0 2 2 2 0 AAA domain Septin PF00735.18 CAR27048.1 - 0.035 13.4 0.2 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Septin AAA_33 PF13671.6 CAR27048.1 - 0.048 13.8 0.0 0.099 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CAR27048.1 - 0.076 12.2 0.4 0.37 9.9 0.1 1.9 1 1 1 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 CAR27048.1 - 0.15 12.1 0.0 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pirin PF02678.16 CAR27049.1 - 8e-26 90.1 0.0 6.7e-25 87.2 0.0 2.2 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 CAR27049.1 - 1.8e-18 66.8 0.0 4e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 CAR27049.1 - 0.0055 16.4 0.3 0.11 12.2 0.3 2.4 2 0 0 2 2 2 1 Cupin domain Alg6_Alg8 PF03155.15 CAR27050.1 - 9.7e-148 493.1 29.5 1.2e-147 492.9 29.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family SGTA_dimer PF16546.5 CAR27051.1 - 2e-19 69.1 2.1 2.8e-19 68.7 1.1 1.8 2 0 0 2 2 2 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 CAR27051.1 - 9.3e-19 66.4 7.3 2e-06 27.4 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR27051.1 - 3.3e-18 64.3 6.0 0.00014 21.7 0.1 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 CAR27051.1 - 1.8e-12 46.7 12.2 1.6e-05 24.5 0.7 4.0 2 1 2 4 4 4 3 TPR repeat TPR_8 PF13181.6 CAR27051.1 - 3e-09 36.4 14.6 0.00072 19.6 0.3 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAR27051.1 - 2.2e-07 31.4 3.6 0.0044 17.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR27051.1 - 5.9e-07 29.7 4.4 2.3e-05 24.6 1.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAR27051.1 - 1.8e-06 28.3 0.5 0.19 12.6 0.0 4.3 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAR27051.1 - 7.2e-06 25.7 1.0 0.053 13.4 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAR27051.1 - 9.4e-06 26.1 2.6 0.0042 17.6 0.2 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR27051.1 - 2.2e-05 24.5 2.4 0.0045 17.3 0.1 3.7 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAR27051.1 - 3.6e-05 23.5 4.4 0.43 10.7 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAR27051.1 - 6.7e-05 23.3 1.5 0.027 15.1 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat GerD PF17898.1 CAR27051.1 - 0.0097 15.8 0.6 0.023 14.6 0.6 1.6 1 0 0 1 1 1 1 Spore germination GerD central core domain BTAD PF03704.17 CAR27051.1 - 0.01 16.2 0.4 0.07 13.6 0.1 2.5 1 1 2 3 3 3 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 CAR27051.1 - 0.19 11.8 3.7 16 5.7 0.1 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CAR27051.1 - 0.41 10.9 3.0 5.9 7.2 3.2 2.5 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 CAR27051.1 - 0.56 10.3 4.9 7 6.7 1.9 3.7 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) STI1 PF17830.1 CAR27051.1 - 0.75 9.8 17.8 0.56 10.2 13.6 2.4 1 1 0 2 2 2 0 STI1 domain DUF5113 PF17140.4 CAR27051.1 - 0.92 9.3 3.6 6.1 6.6 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5113) MIT PF04212.18 CAR27051.1 - 3.1 7.9 14.1 8.8 6.5 0.1 4.2 5 1 0 5 5 3 0 MIT (microtubule interacting and transport) domain VPS9 PF02204.18 CAR27052.1 - 5.1e-12 45.9 0.2 5e-11 42.7 0.2 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 CAR27052.1 - 6.5e-08 33.1 0.7 0.0018 18.8 0.1 3.7 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAR27052.1 - 1.9e-07 31.2 0.1 0.001 19.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAR27052.1 - 0.074 13.6 0.1 76 4.4 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeat Ribo_biogen_C PF04034.13 CAR27053.1 - 3.9e-50 168.8 0.0 5.5e-50 168.4 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CAR27053.1 - 1.3e-14 53.7 0.2 2.3e-14 52.9 0.2 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI CDC45 PF02724.14 CAR27053.1 - 0.029 12.7 6.3 0.041 12.2 6.3 1.3 1 0 0 1 1 1 0 CDC45-like protein SKA1 PF07160.12 CAR27053.1 - 0.19 11.6 5.2 0.31 10.9 5.2 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Ribosomal_60s PF00428.19 CAR27053.1 - 0.22 12.1 17.2 0.41 11.3 17.2 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4746 PF15928.5 CAR27053.1 - 0.31 10.4 15.9 0.46 9.9 15.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Radial_spoke PF04712.12 CAR27053.1 - 1.4 7.8 14.6 1.9 7.3 14.6 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Spore_coat_CotO PF14153.6 CAR27053.1 - 3.2 7.7 13.3 5.6 6.9 13.3 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Nop53 PF07767.11 CAR27053.1 - 4.4 6.6 23.0 0.32 10.4 18.1 1.5 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 CAR27053.1 - 5 5.2 19.0 6.9 4.8 19.0 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 CAR27053.1 - 7.3 6.8 23.3 0.74 10.0 18.7 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_ligase_A_M PF01068.21 CAR27054.1 - 1.6e-48 165.1 0.0 2.7e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CAR27054.1 - 1.8e-26 93.5 0.1 3.3e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 CAR27054.1 - 8.2e-16 58.2 0.0 3.8e-09 36.8 0.0 3.1 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CAR27054.1 - 4.5e-09 36.6 0.0 1.5e-05 25.2 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.15 CAR27054.1 - 5.6e-05 23.7 0.1 0.00012 22.6 0.1 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CAR27054.1 - 0.00012 22.4 0.0 0.00034 21.0 0.0 1.8 1 1 0 1 1 1 1 RNA ligase DNA_ligase_IV PF11411.8 CAR27054.1 - 0.007 16.5 0.2 0.017 15.2 0.2 1.6 1 0 0 1 1 1 1 DNA ligase IV NPR2 PF06218.11 CAR27055.1 - 2.2e-128 428.8 6.3 2.2e-128 428.8 6.3 1.9 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Kinesin PF00225.23 CAR27056.1 - 1.4e-96 323.4 21.3 2.6e-63 214.0 8.7 3.5 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CAR27056.1 - 5.7e-21 75.0 0.0 5.7e-21 75.0 0.0 3.5 5 0 0 5 5 5 1 Microtubule binding Scm3 PF10384.9 CAR27056.1 - 0.023 14.4 0.5 0.15 11.8 0.1 2.8 2 0 0 2 2 2 0 Centromere protein Scm3 RPA43_OB PF17875.1 CAR27056.1 - 1.8 9.2 7.4 4.6 7.9 3.5 2.6 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Fcf1 PF04900.12 CAR27057.1 - 8.2e-35 119.2 0.5 1.6e-34 118.2 0.5 1.5 1 0 0 1 1 1 1 Fcf1 Nucleo_P87 PF07267.11 CAR27057.1 - 7.4 5.3 8.6 8.9 5.0 8.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Peptidase_S8 PF00082.22 CAR27058.1 - 3.5e-33 115.1 8.1 6.5e-33 114.3 8.1 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CAR27058.1 - 1.8e-07 31.7 0.0 3.4e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Lyase_1 PF00206.20 CAR27059.1 - 1.2e-118 396.0 0.1 1.6e-118 395.7 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CAR27059.1 - 1.3e-24 86.4 0.3 5.1e-23 81.2 0.0 2.6 2 0 0 2 2 2 1 Fumarase C C-terminus ADH_N PF08240.12 CAR27059.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Sulfate_transp PF00916.20 CAR27060.1 - 1.1e-76 258.1 21.7 1.6e-76 257.6 21.7 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CAR27060.1 - 2.1e-16 59.6 1.2 4.4e-16 58.6 1.2 1.6 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 CAR27060.1 - 0.0028 17.7 0.0 0.0055 16.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain SWIRM PF04433.17 CAR27061.1 - 3.6e-28 97.7 0.1 9.7e-28 96.4 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 CAR27061.1 - 7e-21 74.0 11.5 7e-21 74.0 11.5 2.4 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CAR27061.1 - 3.6e-10 39.9 0.0 1.2e-09 38.2 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR27061.1 - 5.1e-08 33.0 0.2 5.1e-08 33.0 0.2 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain CASP_C PF08172.12 CAR27062.1 - 1.2e-69 234.4 6.9 1.2e-69 234.4 6.9 3.9 3 1 1 4 4 4 1 CASP C terminal ADIP PF11559.8 CAR27062.1 - 0.0005 20.2 4.1 0.0005 20.2 4.1 6.7 4 1 1 6 6 6 2 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 CAR27062.1 - 0.0068 16.9 1.9 0.0068 16.9 1.9 5.6 4 2 1 5 5 5 1 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 CAR27062.1 - 0.013 15.8 1.9 0.013 15.8 1.9 7.2 5 2 3 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BRI3BP PF14965.6 CAR27062.1 - 4.9 6.6 8.5 0.33 10.4 0.3 2.9 3 0 0 3 3 3 0 Negative regulator of p53/TP53 DUF2304 PF10066.9 CAR27062.1 - 6 7.1 7.8 2.2 8.5 0.2 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Mannitol_dh PF01232.23 CAR27062.1 - 7.6 6.7 8.7 0.65 10.2 1.9 2.8 2 1 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain Ribosomal_L22 PF00237.19 CAR27063.1 - 3.1e-37 126.9 0.5 3.1e-37 126.9 0.5 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Ribonuc_L-PSP PF01042.21 CAR27064.1 - 4.8e-40 136.3 0.2 5.7e-40 136.1 0.2 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP RhoGEF PF00621.20 CAR27064.1 - 0.031 14.5 0.1 0.037 14.3 0.1 1.2 1 0 0 1 1 1 0 RhoGEF domain PET117 PF15786.5 CAR27065.1 - 4.3e-30 103.8 6.6 2.2e-29 101.5 6.6 1.9 1 1 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Cyclin PF08613.11 CAR27066.1 - 2.7e-43 148.1 7.5 9.5e-26 91.1 0.0 3.1 3 0 0 3 3 3 2 Cyclin DUF3192 PF11399.8 CAR27066.1 - 0.013 15.4 2.0 0.017 15.1 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3192) Herpes_BLLF1 PF05109.13 CAR27066.1 - 0.073 11.1 3.1 0.095 10.7 3.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) MAS20 PF02064.15 CAR27066.1 - 0.38 10.9 4.1 22 5.1 0.0 2.7 2 1 0 2 2 2 0 MAS20 protein import receptor ALMT PF11744.8 CAR27066.1 - 8.4 5.1 13.4 1.9 7.2 9.8 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter Transp_cyt_pur PF02133.15 CAR27067.1 - 8.1e-87 291.8 36.2 9.4e-87 291.6 36.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ketoacyl-synt PF00109.26 CAR27068.1 - 1.3e-59 201.9 0.0 1.7e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CAR27068.1 - 7.3e-31 106.6 0.1 1.3e-30 105.8 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 CAR27068.1 - 0.0035 16.7 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain HAD_2 PF13419.6 CAR27069.1 - 1.7e-15 57.6 0.0 2.1e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR27069.1 - 1e-12 48.8 0.0 1.9e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAR27069.1 - 0.013 15.9 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR27069.1 - 0.024 14.7 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like YmzC PF14157.6 CAR27069.1 - 0.13 12.4 0.4 0.22 11.6 0.4 1.4 1 0 0 1 1 1 0 YmzC-like protein Tho1_MOS11_C PF18592.1 CAR27070.1 - 3.9e-26 90.6 0.4 3.9e-26 90.6 0.4 2.0 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain SAP PF02037.27 CAR27070.1 - 2.8e-12 46.1 0.1 6.2e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 SAP domain Spore_coat_CotO PF14153.6 CAR27070.1 - 0.12 12.3 13.7 0.18 11.7 13.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO eIF-3c_N PF05470.12 CAR27070.1 - 0.73 8.1 10.8 0.9 7.8 10.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 CAR27070.1 - 1.8 6.8 11.5 2 6.6 11.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 CAR27070.1 - 2.2 6.7 8.0 3.4 6.1 8.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GREB1 PF15782.5 CAR27070.1 - 2.3 5.3 8.5 2.5 5.1 8.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Roughex PF06020.11 CAR27070.1 - 2.9 6.9 13.2 3.5 6.6 13.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DUF2151 PF10221.9 CAR27070.1 - 3.2 6.2 9.8 3.9 5.9 9.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Neur_chan_memb PF02932.16 CAR27070.1 - 9.4 6.2 5.9 12 5.9 5.9 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 CAR27070.1 - 9.7 5.9 14.9 15 5.3 14.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Vhr1 PF04001.13 CAR27072.1 - 1.2e-45 153.7 1.7 2.4e-45 152.8 1.7 1.5 1 0 0 1 1 1 1 Transcription factor Vhr1 ICL PF00463.21 CAR27073.1 - 9.7e-277 918.6 0.4 1.1e-276 918.4 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CAR27073.1 - 4.4e-10 39.4 0.1 1.3e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase EF-hand_11 PF08976.11 CAR27074.1 - 0.1 13.5 0.1 0.13 13.2 0.1 1.0 1 0 0 1 1 1 0 EF-hand domain RGI1 PF10843.8 CAR27075.1 - 5.5e-30 104.5 7.7 1.1e-29 103.5 7.7 1.4 1 1 0 1 1 1 1 Respiratory growth induced protein 1 DUF5100 PF17029.5 CAR27075.1 - 0.11 12.3 0.9 0.19 11.6 0.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5100) zf-RING_4 PF14570.6 CAR27076.1 - 1.9e-20 72.4 13.5 3.5e-20 71.5 13.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CAR27076.1 - 8.2e-07 28.8 8.0 1.6e-06 27.9 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 CAR27076.1 - 9.4e-06 25.6 2.9 2.1e-05 24.5 2.9 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_1 PF00076.22 CAR27076.1 - 0.00014 21.6 0.0 0.012 15.4 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 CAR27076.1 - 0.00018 21.8 10.0 0.00035 20.8 10.0 1.5 1 0 0 1 1 1 1 Ring finger domain Rtf2 PF04641.12 CAR27076.1 - 0.00069 19.1 1.3 0.00069 19.1 1.3 2.6 3 0 0 3 3 3 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 CAR27076.1 - 0.0022 17.8 11.2 0.0045 16.8 11.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SET_assoc PF11767.8 CAR27076.1 - 0.0034 17.0 0.2 0.012 15.3 0.1 1.9 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 CAR27076.1 - 0.0064 16.3 8.7 0.076 12.9 9.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 PNISR PF15996.5 CAR27076.1 - 0.019 15.3 17.6 0.4 10.9 7.6 3.0 3 0 0 3 3 3 0 Arginine/serine-rich protein PNISR zf-RING_UBOX PF13445.6 CAR27076.1 - 0.057 13.4 9.5 0.16 12.0 9.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-UDP PF14569.6 CAR27076.1 - 0.12 12.5 4.7 0.27 11.4 4.7 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger EOS1 PF12326.8 CAR27076.1 - 0.17 11.8 3.6 1 9.2 0.5 2.6 3 0 0 3 3 3 0 N-glycosylation protein RskA PF10099.9 CAR27076.1 - 0.2 11.9 27.0 1.9 8.8 17.8 2.4 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Hid1 PF12722.7 CAR27076.1 - 0.44 8.6 7.7 0.86 7.7 7.7 1.5 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-RING_5 PF14634.6 CAR27076.1 - 0.55 10.2 10.2 1.2 9.2 10.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF4746 PF15928.5 CAR27076.1 - 1.1 8.6 9.4 0.38 10.1 2.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Sec62 PF03839.16 CAR27076.1 - 3 7.3 9.9 2.5 7.5 4.8 2.4 2 0 0 2 2 2 0 Translocation protein Sec62 Pet20 PF08692.10 CAR27076.1 - 3.6 8.3 6.7 2.4 8.9 2.8 2.5 3 0 0 3 3 2 0 Mitochondrial protein Pet20 Pinin_SDK_memA PF04696.13 CAR27076.1 - 4.1 7.5 28.4 0.12 12.4 11.3 2.9 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region RPN2_C PF18004.1 CAR27076.1 - 6 6.8 17.5 10 6.0 9.9 2.5 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPL5 PF18168.1 CAR27076.1 - 7.7 5.7 11.8 0.78 9.0 5.8 2.1 2 0 0 2 2 2 0 Prim-pol family 5 zf-C3HC4_2 PF13923.6 CAR27076.1 - 8 6.4 9.9 19 5.2 9.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Paf1 PF03985.13 CAR27076.1 - 8.6 5.2 22.9 4.8 6.1 0.5 2.2 2 0 0 2 2 2 0 Paf1 U1snRNP70_N PF12220.8 CAR27077.1 - 1.9e-23 82.9 3.7 5.7e-23 81.4 2.3 2.1 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CAR27077.1 - 3.2e-18 65.3 0.0 7.5e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR27077.1 - 3.6e-06 27.0 0.0 9.4e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif NAT PF04768.13 CAR27078.1 - 3.9e-54 182.9 0.1 1.3e-53 181.2 0.0 1.9 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 CAR27078.1 - 1.8e-28 99.4 0.0 3.9e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 CAR27078.1 - 5.6e-25 88.3 0.0 1.1e-24 87.4 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 CAR27078.1 - 0.021 15.0 0.0 0.064 13.4 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus P16-Arc PF04699.14 CAR27079.1 - 3.5e-47 160.6 0.0 3.9e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.12 CAR27079.1 - 0.018 15.4 0.0 0.04 14.2 0.0 1.5 2 0 0 2 2 2 0 Dip2/Utp12 Family Ran_BP1 PF00638.18 CAR27080.1 - 1.3e-34 119.0 0.1 3.9e-34 117.5 0.1 1.8 1 0 0 1 1 1 1 RanBP1 domain Methyltransf_31 PF13847.6 CAR27081.1 - 6.2e-27 94.3 0.0 9.1e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR27081.1 - 4.5e-10 40.1 0.0 7.5e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR27081.1 - 2.4e-08 34.6 0.0 4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR27081.1 - 1.5e-06 28.8 0.0 2.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CAR27081.1 - 3.6e-06 26.6 0.0 6.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 CAR27081.1 - 3.8e-05 23.7 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CAR27081.1 - 0.00012 21.5 0.0 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CAR27081.1 - 0.00037 20.4 0.0 0.0005 19.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CAR27081.1 - 0.0017 18.3 0.0 0.0025 17.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CAR27081.1 - 0.0069 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 CAR27081.1 - 0.047 13.1 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Fis1_TPR_C PF14853.6 CAR27082.1 - 2e-26 91.8 0.1 2.9e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CAR27082.1 - 4.6e-15 55.0 0.1 7.4e-15 54.3 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.6 CAR27082.1 - 0.016 15.7 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat SKG6 PF08693.10 CAR27082.1 - 0.017 14.5 1.4 0.028 13.8 1.4 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ribonuc_red_lgC PF02867.15 CAR27083.1 - 7.1e-185 615.5 0.0 8.8e-185 615.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CAR27083.1 - 4.5e-22 77.8 0.0 1.1e-21 76.6 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CAR27083.1 - 2e-17 63.5 0.0 5e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 ATP cone domain LCCL PF03815.19 CAR27084.1 - 6.1e-09 35.9 0.3 1.1e-08 35.1 0.3 1.4 1 0 0 1 1 1 1 LCCL domain Sec6 PF06046.13 CAR27085.1 - 6.1e-169 563.1 13.1 7.6e-169 562.8 13.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 USP8_interact PF08941.10 CAR27085.1 - 0.014 15.2 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 0 USP8 interacting Alb1 PF09135.11 CAR27085.1 - 3.2 8.7 5.2 2.8 8.8 2.2 2.2 2 0 0 2 2 2 0 Alb1 Vps53_N PF04100.12 CAR27085.1 - 8.3 5.3 20.4 0.15 11.0 4.2 3.5 4 0 0 4 4 4 0 Vps53-like, N-terminal Tctex-1 PF03645.13 CAR27086.1 - 1.6e-08 34.7 0.0 2e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Tn7_Tnp_TnsA_C PF08721.11 CAR27086.1 - 0.091 13.4 0.1 0.16 12.6 0.1 1.3 1 0 0 1 1 1 0 TnsA endonuclease C terminal DUF3015 PF11220.8 CAR27086.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF5388 PF17363.2 CAR27086.1 - 0.14 12.4 0.3 1.6 9.0 0.1 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5388) DUF202 PF02656.15 CAR27087.1 - 2.6e-14 53.4 4.3 2.6e-14 53.4 4.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Aldedh PF00171.22 CAR27088.1 - 1.2e-181 604.3 0.2 1.4e-181 604.1 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_S24e PF01282.19 CAR27089.1 - 1.4e-33 114.7 0.0 2.7e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S24e RAMPs PF03787.15 CAR27089.1 - 0.049 13.7 0.3 3 7.8 0.0 2.1 2 0 0 2 2 2 0 RAMP superfamily YebF PF13995.6 CAR27089.1 - 0.096 12.7 0.2 0.17 11.9 0.1 1.5 2 0 0 2 2 2 0 YebF-like protein Yos1 PF08571.10 CAR27090.1 - 1.1e-31 108.9 0.4 1.2e-31 108.8 0.4 1.0 1 0 0 1 1 1 1 Yos1-like Y_phosphatase PF00102.27 CAR27091.1 - 2.1e-49 168.2 0.1 3.6e-49 167.5 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 CAR27091.1 - 1.5e-07 31.9 0.0 5.1e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 CAR27091.1 - 0.0066 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CAR27091.1 - 0.051 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain MAM33 PF02330.16 CAR27092.1 - 2.7e-59 200.7 9.0 3.1e-59 200.5 9.0 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF4627 PF15425.6 CAR27092.1 - 0.014 15.0 1.1 0.022 14.4 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4627) DUF2000 PF09391.10 CAR27092.1 - 0.09 12.7 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2000) Cons_hypoth95 PF03602.15 CAR27092.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PPR_2 PF13041.6 CAR27093.1 - 1.3e-18 66.9 0.5 3.5e-12 46.3 0.0 4.0 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.20 CAR27093.1 - 0.18 12.1 0.3 35 4.9 0.0 4.2 6 0 0 6 6 6 0 PPR repeat Peptidase_M24 PF00557.24 CAR27095.1 - 1.1e-51 175.5 0.0 1.9e-51 174.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CAR27095.1 - 3.5e-38 130.1 0.0 8.9e-38 128.8 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HORMA PF02301.18 CAR27096.1 - 7.5e-61 205.4 1.2 1.7e-60 204.3 1.2 1.6 1 0 0 1 1 1 1 HORMA domain APH PF01636.23 CAR27098.1 - 4.1e-06 26.9 0.0 2.7e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CAR27098.1 - 0.068 12.5 0.0 5.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPO22 PF08631.10 CAR27099.1 - 3e-62 210.6 17.4 1.1e-60 205.5 1.5 3.8 3 1 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like Glyoxalase_2 PF12681.7 CAR27099.1 - 0.062 13.2 1.7 0.18 11.8 0.2 2.5 2 0 0 2 2 2 0 Glyoxalase-like domain 2-Hacid_dh_C PF02826.19 CAR27100.1 - 1.4e-52 177.6 0.0 2.1e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAR27100.1 - 1.2e-38 131.9 0.0 1.5e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 CAR27100.1 - 6.9e-05 22.5 0.0 0.00022 20.9 0.0 1.9 1 0 0 1 1 1 1 ACT domain NAD_binding_2 PF03446.15 CAR27100.1 - 7.8e-05 22.9 0.4 0.00042 20.5 0.1 2.2 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 CAR27100.1 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 CAR27100.1 - 0.0052 17.3 0.1 0.014 15.9 0.0 1.7 2 0 0 2 2 2 1 XdhC Rossmann domain IlvN PF07991.12 CAR27100.1 - 0.11 12.0 0.1 0.65 9.6 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain RPN2_C PF18004.1 CAR27101.1 - 2.4e-52 177.1 8.2 3.6e-52 176.5 8.2 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CAR27101.1 - 5.2e-32 108.6 30.9 5.2e-05 23.5 0.4 9.0 10 0 0 10 10 10 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CAR27101.1 - 2e-16 60.1 4.2 3.7e-14 52.9 0.4 4.4 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 CAR27101.1 - 9.8e-08 32.3 2.0 0.57 10.8 0.1 4.4 4 0 0 4 4 4 3 HEAT-like repeat HEAT PF02985.22 CAR27101.1 - 1.5e-06 27.9 2.7 0.99 9.8 0.1 4.7 4 0 0 4 4 4 3 HEAT repeat Cnd1 PF12717.7 CAR27101.1 - 0.017 15.2 1.8 2.3 8.3 0.1 3.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 CAR27101.1 - 0.096 13.4 3.2 41 5.3 0.1 4.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 CAR27101.1 - 0.1 12.8 0.0 0.73 10.1 0.0 2.6 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 MRNIP PF15749.5 CAR27101.1 - 0.1 13.3 4.2 0.21 12.3 4.2 1.4 1 0 0 1 1 1 0 MRN-interacting protein NARP1 PF12569.8 CAR27101.1 - 1.6 7.6 10.3 2.7 6.8 10.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Striatin PF08232.12 CAR27101.1 - 4.1 8.0 8.7 7.3 7.2 8.7 1.3 1 0 0 1 1 1 0 Striatin family BING4CT PF08149.11 CAR27102.1 - 5.5e-37 125.4 0.6 1.2e-34 118.0 0.0 3.6 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.32 CAR27102.1 - 4.8e-07 30.4 0.4 0.0029 18.4 0.0 4.8 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27102.1 - 4.1e-06 27.0 0.0 3.2 8.1 0.0 4.4 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CAR27102.1 - 0.05 13.2 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain DHO_dh PF01180.21 CAR27103.1 - 1.1e-97 326.8 0.1 1.3e-97 326.6 0.1 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CAR27103.1 - 3.5e-05 23.0 0.1 0.066 12.2 0.3 2.7 2 1 0 2 2 2 2 FMN-dependent dehydrogenase GET2 PF08690.10 CAR27104.1 - 3.9e-70 237.0 10.2 7.9e-68 229.4 10.2 2.0 1 1 0 1 1 1 1 GET complex subunit GET2 HAUS-augmin3 PF14932.6 CAR27104.1 - 0.099 12.2 0.3 0.17 11.4 0.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 POX PF07526.11 CAR27104.1 - 0.13 12.9 0.4 0.43 11.1 0.1 1.9 2 0 0 2 2 2 0 Associated with HOX Coatomer_E PF04733.14 CAR27105.1 - 2.9e-13 49.9 11.2 6e-13 48.9 11.2 1.5 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 CAR27105.1 - 5.1e-05 23.7 1.8 0.043 14.3 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAR27105.1 - 0.006 17.3 0.0 18 6.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAR27105.1 - 0.016 15.8 3.7 14 6.6 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 CAR27105.1 - 0.11 13.2 0.1 4.5 8.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4167 PF13763.6 CAR27105.1 - 0.3 11.2 0.0 0.3 11.2 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4167) DUF1689 PF07954.11 CAR27106.1 - 1.7e-55 187.4 1.3 2.3e-55 187.0 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) tRNA-synt_2b PF00587.25 CAR27107.1 - 1.8e-34 119.3 0.0 3e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CAR27107.1 - 6.5e-21 74.3 0.6 1.8e-20 72.9 0.5 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 CAR27107.1 - 1.6e-14 53.7 0.0 3.4e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 CAR27107.1 - 1.1e-11 44.6 0.0 2.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain TcpQ PF10671.9 CAR27107.1 - 0.3 11.3 1.0 5.3 7.2 0.0 3.0 3 0 0 3 3 3 0 Toxin co-regulated pilus biosynthesis protein Q zf-CCHC PF00098.23 CAR27108.1 - 9.9e-10 38.1 46.7 0.00017 21.5 3.4 4.9 5 0 0 5 5 5 3 Zinc knuckle zf-C2H2_10 PF16588.5 CAR27108.1 - 0.00013 21.6 2.6 0.00013 21.6 2.6 4.5 4 1 1 5 5 5 1 C2H2 zinc-finger zf-CCHC_2 PF13696.6 CAR27108.1 - 0.00035 20.3 1.8 0.00035 20.3 1.8 5.1 5 0 0 5 5 5 3 Zinc knuckle TFIIF_alpha PF05793.12 CAR27108.1 - 0.13 10.9 6.4 0.16 10.5 6.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-CCHC_3 PF13917.6 CAR27108.1 - 0.91 9.5 0.1 0.91 9.5 0.1 4.3 2 1 2 4 4 4 0 Zinc knuckle Pmp3 PF01679.17 CAR27109.1 - 4.6e-22 77.9 5.9 6.9e-22 77.4 5.9 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator UPF0029 PF01205.19 CAR27111.1 - 1.9e-32 111.7 0.1 3.2e-32 111.0 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized protein family UPF0029 DUF1317 PF07026.11 CAR27111.1 - 0.046 13.5 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) Aldo_ket_red PF00248.21 CAR27112.1 - 5.8e-38 130.8 0.0 8.7e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family FAD-oxidase_C PF02913.19 CAR27113.1 - 8.3e-63 212.3 0.0 1.1e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CAR27113.1 - 1.8e-34 118.5 0.1 3.2e-34 117.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HIT PF01230.23 CAR27114.1 - 9.3e-22 77.6 0.2 1.6e-21 76.9 0.2 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CAR27114.1 - 1.9e-05 25.1 0.5 3e-05 24.4 0.5 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CAR27114.1 - 0.011 15.5 0.4 0.032 14.1 0.3 1.8 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 AAA PF00004.29 CAR27115.1 - 2.3e-98 325.8 0.0 2.8e-48 163.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR27115.1 - 1.1e-23 82.7 5.3 9.8e-13 47.7 1.6 2.7 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CAR27115.1 - 1.6e-18 66.6 0.5 5.3e-18 65.0 0.5 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CAR27115.1 - 9.1e-14 51.5 0.0 1.5e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CAR27115.1 - 2.6e-13 50.4 0.0 6e-07 29.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CAR27115.1 - 4.3e-13 50.0 0.0 0.0001 22.8 0.0 4.5 3 2 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 CAR27115.1 - 1.7e-11 44.5 0.0 7.4e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CAR27115.1 - 2.7e-11 43.6 1.6 9.9e-06 25.6 0.1 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) CDC48_2 PF02933.17 CAR27115.1 - 4e-10 39.3 0.0 1e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.13 CAR27115.1 - 3e-09 36.6 0.1 0.0016 17.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 CAR27115.1 - 7.9e-09 35.9 1.0 0.074 13.3 0.0 4.2 2 2 2 4 4 4 2 AAA domain Vps4_C PF09336.10 CAR27115.1 - 8.3e-08 32.1 0.3 1.3e-05 25.1 0.0 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 CAR27115.1 - 3.3e-07 30.7 0.0 0.013 15.9 0.0 2.9 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 CAR27115.1 - 3.6e-07 29.8 0.4 0.026 13.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CAR27115.1 - 3.7e-07 30.2 0.0 0.024 14.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 CAR27115.1 - 1e-06 28.6 0.0 0.031 14.0 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 CAR27115.1 - 2.5e-06 27.0 1.8 0.52 9.6 0.0 3.9 3 1 0 4 4 4 2 KaiC AAA_18 PF13238.6 CAR27115.1 - 7.5e-06 26.5 0.0 0.23 12.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CAR27115.1 - 7.8e-06 25.7 0.0 0.089 12.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CAR27115.1 - 9.3e-06 25.3 0.1 0.085 12.4 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 CAR27115.1 - 1.9e-05 24.5 0.1 0.2 11.3 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CAR27115.1 - 2.5e-05 23.5 0.0 0.15 11.1 0.0 2.6 3 0 0 3 3 3 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 CAR27115.1 - 4.8e-05 22.9 0.5 0.19 11.2 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_28 PF13521.6 CAR27115.1 - 5.4e-05 23.5 0.0 0.56 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 CAR27115.1 - 5.6e-05 23.1 0.1 0.14 11.9 0.0 3.1 4 0 0 4 4 3 2 Bacterial dnaA protein ABC_tran PF00005.27 CAR27115.1 - 7.7e-05 23.2 0.0 0.11 13.0 0.0 3.6 2 1 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 CAR27115.1 - 8e-05 22.3 6.5 0.32 10.6 0.2 4.3 2 2 2 4 4 4 1 AAA domain AAA_17 PF13207.6 CAR27115.1 - 0.00012 22.5 0.0 0.57 10.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 CAR27115.1 - 0.00017 21.4 0.0 0.79 9.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CAR27115.1 - 0.00032 20.7 0.0 0.55 10.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CAR27115.1 - 0.00045 19.4 0.0 0.45 9.6 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ResIII PF04851.15 CAR27115.1 - 0.00053 20.0 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CAR27115.1 - 0.00062 19.6 1.7 1 9.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF2075 PF09848.9 CAR27115.1 - 0.00067 19.0 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CAR27115.1 - 0.0011 18.7 0.2 2.2 8.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CAR27115.1 - 0.0012 18.8 0.1 2.2 8.2 0.0 3.3 3 0 0 3 3 3 1 NACHT domain ATPase_2 PF01637.18 CAR27115.1 - 0.0014 18.6 0.1 20 5.0 0.0 3.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CAR27115.1 - 0.0065 16.8 1.9 3.5 8.0 0.0 3.2 3 1 0 4 4 2 1 AAA domain IPT PF01745.16 CAR27115.1 - 0.015 14.7 0.1 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activ_2 PF14532.6 CAR27115.1 - 0.016 15.4 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CAR27115.1 - 0.018 14.3 0.0 7.1 5.9 0.0 3.0 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 CAR27115.1 - 0.03 14.2 1.3 8.2 6.3 0.0 4.1 4 0 0 4 4 4 0 NTPase NB-ARC PF00931.22 CAR27115.1 - 0.03 13.5 0.0 5.3 6.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Zot PF05707.12 CAR27115.1 - 0.044 13.4 0.0 2.8 7.6 0.0 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 CAR27115.1 - 0.048 13.4 0.1 7.9 6.1 0.0 2.8 3 0 0 3 3 2 0 Cytidylate kinase KAP_NTPase PF07693.14 CAR27115.1 - 0.053 12.8 0.3 2.2 7.5 0.0 2.8 2 2 0 2 2 2 0 KAP family P-loop domain AAA_6 PF12774.7 CAR27115.1 - 0.11 11.4 0.3 5.1 6.0 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region Cyclin_N PF00134.23 CAR27116.1 - 2e-16 59.9 0.1 4e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CAR27116.1 - 1.3e-06 28.9 0.0 1.3e-06 28.9 0.0 1.9 2 1 0 2 2 2 1 Cyclin Na_Ca_ex PF01699.24 CAR27117.1 - 8.8e-49 165.3 32.4 2.7e-26 92.4 5.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Tad PF13400.6 CAR27117.1 - 0.95 9.8 8.6 8.2 6.8 0.3 3.9 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like DPM3 PF08285.11 CAR27117.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.5 3 1 1 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) SirB PF04247.12 CAR27117.1 - 4.9 7.3 11.7 0.16 12.1 1.2 3.2 3 1 0 3 3 3 0 Invasion gene expression up-regulator, SirB RanGAP1_C PF07834.11 CAR27119.1 - 0.026 14.2 0.1 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 RanGAP1 C-terminal domain Ribosomal_60s PF00428.19 CAR27120.1 - 2.8e-23 82.3 7.8 3.4e-23 82.0 7.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein MTTB PF06253.11 CAR27120.1 - 0.083 10.8 0.0 0.094 10.7 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) IATP PF04568.12 CAR27121.1 - 2.1e-13 50.5 0.6 2.4e-13 50.3 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HisKA PF00512.25 CAR27121.1 - 0.0038 17.2 0.3 0.0073 16.3 0.3 1.4 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Matrilin_ccoil PF10393.9 CAR27121.1 - 0.071 13.0 1.2 0.1 12.5 1.2 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin PspB PF06667.12 CAR27121.1 - 0.11 12.6 0.6 0.15 12.1 0.6 1.2 1 0 0 1 1 1 0 Phage shock protein B DivIC PF04977.15 CAR27121.1 - 0.11 12.3 2.2 0.15 11.9 2.2 1.2 1 0 0 1 1 1 0 Septum formation initiator HMGL-like PF00682.19 CAR27122.1 - 4.6e-84 282.1 0.1 7.3e-84 281.4 0.1 1.3 1 0 0 1 1 1 1 HMGL-like Cullin PF00888.22 CAR27123.1 - 1.5e-149 499.5 11.5 2e-149 499.1 11.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CAR27123.1 - 4.9e-24 84.1 1.1 2e-23 82.2 1.1 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain PDZ_4 PF17816.1 CAR27123.1 - 0.092 13.1 0.0 0.27 11.6 0.0 1.8 1 0 0 1 1 1 0 PDZ domain MARVEL PF01284.23 CAR27124.1 - 0.029 14.4 1.7 0.066 13.2 1.7 1.5 1 1 0 1 1 1 0 Membrane-associating domain MIG-14_Wnt-bd PF06664.12 CAR27124.1 - 0.1 11.8 2.3 0.21 10.8 2.3 1.5 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Mit_KHE1 PF10173.9 CAR27125.1 - 3.7e-53 180.4 3.0 4.7e-53 180.1 3.0 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related ATP-synt_ab PF00006.25 CAR27126.1 - 1.8e-113 377.4 0.0 6.9e-113 375.5 0.0 1.9 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.16 CAR27126.1 - 1.5e-83 280.2 0.1 2.5e-83 279.5 0.1 1.4 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.14 CAR27126.1 - 1.6e-50 169.9 0.1 6e-34 116.5 0.1 2.5 2 0 0 2 2 2 2 Homing endonuclease ATP-synt_ab_Xtn PF16886.5 CAR27126.1 - 1.2e-45 154.3 0.0 3.1e-45 153.0 0.0 1.7 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CAR27126.1 - 4.2e-15 56.0 2.7 4.2e-15 56.0 2.7 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Hint PF01079.20 CAR27126.1 - 0.0012 18.4 0.1 0.003 17.1 0.1 1.6 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 CAR27126.1 - 0.0015 18.8 0.0 0.0048 17.2 0.0 1.9 1 0 0 1 1 1 1 Hint domain LAGLIDADG_3 PF14528.6 CAR27126.1 - 0.005 17.1 0.1 1.6 9.1 0.0 2.7 2 0 0 2 2 2 1 LAGLIDADG-like domain Vint PF14623.6 CAR27126.1 - 0.011 15.5 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Hint-domain Mso1_Sec1_bdg PF14475.6 CAR27126.1 - 0.26 10.9 1.0 1.1 9.0 0.3 2.4 2 0 0 2 2 2 0 Sec1-binding region of Mso1 LRR_6 PF13516.6 CAR27127.1 - 0.014 15.4 2.5 9.6 6.6 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat DUF4350 PF14258.6 CAR27127.1 - 0.053 14.0 0.0 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) SOCS_box PF07525.16 CAR27127.1 - 0.51 10.8 2.9 1 9.7 0.1 2.6 2 0 0 2 2 2 0 SOCS box LRR_4 PF12799.7 CAR27127.1 - 0.64 10.5 18.0 1.2 9.6 0.4 5.1 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Ribosomal_L22 PF00237.19 CAR27129.1 - 2.5e-21 75.9 0.0 3.7e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e SHR3_chaperone PF08229.11 CAR27130.1 - 7.5e-70 233.7 0.2 7.5e-70 233.7 0.2 1.6 2 0 0 2 2 2 1 ER membrane protein SH3 Zip PF02535.22 CAR27130.1 - 0.0004 19.7 0.0 0.00053 19.3 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter GAPT PF11770.8 CAR27130.1 - 0.025 14.4 0.5 0.042 13.7 0.5 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) MLANA PF14991.6 CAR27130.1 - 0.047 14.0 0.5 3.1 8.1 0.0 2.5 2 1 0 2 2 2 0 Protein melan-A PepSY_TM PF03929.16 CAR27130.1 - 0.11 12.2 0.0 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 PepSY-associated TM region DUF445 PF04286.12 CAR27130.1 - 0.34 10.7 5.9 0.48 10.2 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PET10 PF17316.2 CAR27130.1 - 0.89 9.0 6.6 1.3 8.4 6.6 1.2 1 0 0 1 1 1 0 Petite colonies protein 10 Presenilin PF01080.17 CAR27130.1 - 2.1 7.0 7.3 3.6 6.3 7.3 1.5 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 CAR27130.1 - 8.6 6.1 15.4 12 5.6 15.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_S3_C PF00189.20 CAR27131.1 - 7e-23 81.0 1.1 1.5e-22 79.9 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CAR27131.1 - 3e-12 46.2 0.1 1.3e-11 44.2 0.1 1.9 2 0 0 2 2 2 1 KH domain Ras PF00071.22 CAR27132.1 - 5.1e-48 162.7 0.0 7.2e-48 162.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR27132.1 - 3.8e-21 75.5 0.0 2.4e-20 73.0 0.0 2.2 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR27132.1 - 0.00015 21.3 0.0 0.00033 20.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family U79_P34 PF03064.16 CAR27132.1 - 0.032 13.6 1.7 0.054 12.9 1.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MMR_HSR1 PF01926.23 CAR27132.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MAP65_ASE1 PF03999.12 CAR27132.1 - 0.087 11.5 15.1 0.12 11.1 15.1 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) GTP_EFTU PF00009.27 CAR27132.1 - 0.089 12.3 0.0 0.44 10.1 0.0 2.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Drf_GBD PF06371.13 CAR27132.1 - 0.47 10.0 6.1 0.82 9.2 6.1 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain adh_short PF00106.25 CAR27133.1 - 2.3e-08 33.7 0.0 1.5e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CAR27133.1 - 2.6e-06 27.5 0.0 4.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 CAR27133.1 - 4e-05 23.3 0.0 6.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase WD40 PF00400.32 CAR27134.1 - 2.7e-05 24.8 1.8 0.42 11.6 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27134.1 - 0.00021 21.5 0.3 0.03 14.6 0.0 3.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CAR27134.1 - 0.2 12.2 0.7 42 4.8 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain RRM_1 PF00076.22 CAR27135.1 - 4.9e-06 26.3 0.0 9.8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Flavodoxin_3 PF12641.7 CAR27135.1 - 0.14 11.8 0.2 0.14 11.8 0.2 1.9 3 0 0 3 3 3 0 Flavodoxin domain Pkinase PF00069.25 CAR27136.1 - 3.1e-49 167.7 0.0 4.6e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27136.1 - 1.4e-22 80.2 0.0 2.4e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CAR27136.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CAR27136.1 - 0.014 14.3 0.1 0.026 13.5 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CAR27136.1 - 0.23 10.7 0.0 0.44 9.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ribosomal_L11_N PF03946.14 CAR27137.1 - 4.3e-27 93.8 0.3 7.7e-27 92.9 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CAR27137.1 - 4.5e-27 94.4 0.7 6.7e-27 93.8 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain UCH PF00443.29 CAR27138.1 - 5.1e-47 160.5 12.1 1.4e-46 159.1 12.1 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR27138.1 - 5.1e-11 42.7 14.1 4.1e-09 36.5 14.1 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_7 PF02591.15 CAR27138.1 - 0.043 14.0 0.8 0.48 10.6 0.0 2.5 2 0 0 2 2 2 0 C4-type zinc ribbon domain TERB2 PF15101.6 CAR27138.1 - 0.34 10.9 13.0 0.39 10.7 0.4 2.7 2 0 0 2 2 2 0 Telomere-associated protein TERB2 ESM4 PF15952.5 CAR27138.1 - 2 8.8 20.4 0.018 15.5 5.8 2.8 2 0 0 2 2 2 0 Enhancer of split M4 family ELFV_dehydrog PF00208.21 CAR27139.1 - 1.5e-62 211.5 0.0 2.7e-62 210.7 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CAR27139.1 - 3.4e-18 64.7 0.0 5.9e-13 47.3 0.0 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 CAR27139.1 - 0.0017 18.2 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain JAB PF01398.21 CAR27140.1 - 1.7e-32 111.9 0.0 3e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CAR27140.1 - 8.3e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CAR27140.1 - 0.00029 21.0 0.0 0.00057 20.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Tim17 PF02466.19 CAR27142.1 - 3.4e-38 130.4 5.9 4.3e-38 130.1 5.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.18 CAR27142.1 - 0.09 12.3 0.8 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Arm PF00514.23 CAR27144.1 - 1.6e-88 288.4 15.3 1.8e-13 50.0 0.1 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 CAR27144.1 - 3.2e-27 94.8 5.4 1.2e-26 93.0 5.5 2.0 2 0 0 2 2 1 1 Importin beta binding domain Arm_3 PF16186.5 CAR27144.1 - 4.3e-21 74.2 5.0 1.1e-20 72.9 5.0 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 CAR27144.1 - 3.8e-20 72.0 2.6 0.00028 21.3 0.0 7.3 5 2 3 8 8 8 6 HEAT-like repeat HEAT_2 PF13646.6 CAR27144.1 - 1.2e-16 60.9 0.5 0.0002 21.7 0.0 5.4 2 1 3 5 5 5 4 HEAT repeats HEAT PF02985.22 CAR27144.1 - 1.8e-12 46.4 0.0 0.073 13.4 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat V-ATPase_H_C PF11698.8 CAR27144.1 - 1.9e-06 28.0 0.2 0.094 12.8 0.0 4.3 4 1 0 4 4 4 2 V-ATPase subunit H Arm_2 PF04826.13 CAR27144.1 - 2.4e-05 23.9 0.2 0.18 11.3 0.0 4.1 3 2 1 4 4 4 1 Armadillo-like Adaptin_N PF01602.20 CAR27144.1 - 3.4e-05 22.6 0.0 0.00081 18.1 0.0 2.3 1 1 0 1 1 1 1 Adaptin N terminal region RICTOR_V PF14668.6 CAR27144.1 - 4.9e-05 23.5 0.8 2 8.7 0.0 4.9 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.9 CAR27144.1 - 0.00016 21.6 0.8 0.41 10.7 0.0 4.3 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain NopRA1 PF16201.5 CAR27144.1 - 0.015 14.9 0.0 4.2 6.9 0.0 4.1 1 1 3 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 GATase_4 PF13230.6 CAR27146.1 - 8.6e-16 57.6 0.0 4.3e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 CAR27146.1 - 1.4e-10 41.5 0.0 2.5e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CAR27146.1 - 0.098 12.6 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Glutamine amidotransferase domain Tyr_Deacylase PF02580.16 CAR27147.1 - 7.6e-49 165.9 0.0 8.4e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Ribosomal_L18 PF17135.4 CAR27147.1 - 0.069 12.5 0.0 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein 60S L18 and 50S L18e Chitin_synth_1 PF01644.17 CAR27148.1 - 2.3e-67 226.0 1.2 3.6e-67 225.4 1.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CAR27148.1 - 3.1e-27 94.3 0.1 7.9e-27 93.0 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CAR27148.1 - 1.4e-16 60.2 10.1 1.1e-12 47.4 4.7 2.3 1 1 1 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CAR27148.1 - 1.1e-09 38.5 4.7 4.2e-09 36.6 4.7 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CAR27148.1 - 0.038 13.8 0.0 2.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CAR27148.1 - 0.044 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF3488 PF11992.8 CAR27148.1 - 8.5 5.2 11.3 14 4.5 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) CDC13_N PF16853.5 CAR27150.1 - 4.8e-63 212.5 1.5 4.8e-63 212.5 1.5 2.1 2 0 0 2 2 2 1 Cell division control protein 13 N-terminus Cdc13_OB4_dimer PF18233.1 CAR27150.1 - 1.9e-19 69.9 0.1 5.2e-19 68.5 0.1 1.8 1 1 0 1 1 1 1 Cdc13 OB4 dimerization domain TFIIA PF03153.13 CAR27150.1 - 0.07 13.1 15.2 0.1 12.6 15.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1387 PF07139.11 CAR27150.1 - 0.29 10.8 8.9 0.56 9.9 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CobT PF06213.12 CAR27150.1 - 0.43 9.9 10.6 0.67 9.3 10.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Androgen_recep PF02166.16 CAR27150.1 - 0.88 8.3 13.9 1.4 7.7 13.9 1.2 1 0 0 1 1 1 0 Androgen receptor SbcCD_C PF13558.6 CAR27151.1 - 1.4 9.2 3.3 1.7 9.0 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Macoilin PF09726.9 CAR27152.1 - 1.8 7.0 14.1 2 6.9 14.1 1.1 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 CAR27152.1 - 6.3 5.7 8.3 7.1 5.5 8.3 1.1 1 0 0 1 1 1 0 Mitoguardin RRM_1 PF00076.22 CAR27153.1 - 8.2e-19 67.2 0.0 6.6e-16 57.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 CAR27153.1 - 0.0049 16.9 35.0 0.0049 16.9 35.0 2.9 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 CAR27153.1 - 0.049 12.4 6.6 0.083 11.7 6.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4786 PF16027.5 CAR27153.1 - 0.057 14.0 23.9 0.029 14.9 12.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4786) SLC12 PF03522.15 CAR27153.1 - 0.067 12.2 7.8 0.11 11.5 7.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 CAR27153.1 - 0.14 11.1 14.5 0.2 10.6 14.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SpoIIP PF07454.11 CAR27153.1 - 0.19 11.2 10.1 0.33 10.4 10.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EOS1 PF12326.8 CAR27153.1 - 0.22 11.4 0.6 0.36 10.7 0.6 1.5 1 0 0 1 1 1 0 N-glycosylation protein AP-5_subunit_s1 PF15001.6 CAR27153.1 - 0.3 11.0 8.6 0.5 10.3 8.6 1.2 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 RR_TM4-6 PF06459.12 CAR27153.1 - 0.59 9.9 10.1 1 9.1 10.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EPL1 PF10513.9 CAR27153.1 - 1.2 9.5 15.8 0.022 15.2 7.0 2.5 3 1 0 3 3 2 0 Enhancer of polycomb-like CPSF100_C PF13299.6 CAR27153.1 - 1.6 8.9 12.1 2.8 8.1 8.8 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FAM60A PF15396.6 CAR27153.1 - 1.6 8.7 7.5 3.8 7.4 7.5 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Connexin PF00029.19 CAR27153.1 - 2.9 7.6 6.8 4.4 7.0 6.8 1.2 1 0 0 1 1 1 0 Connexin API5 PF05918.11 CAR27153.1 - 3 6.5 12.2 4.8 5.9 12.2 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) G0-G1_switch_2 PF15103.6 CAR27153.1 - 3.2 8.2 6.4 6.6 7.2 6.4 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF4407 PF14362.6 CAR27153.1 - 3.5 6.9 9.0 5.5 6.2 9.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 CAR27153.1 - 7.2 5.9 15.9 15 4.8 15.9 1.4 1 0 0 1 1 1 0 FAM76 protein Septin PF00735.18 CAR27154.1 - 2.8e-73 246.7 1.0 2.1e-65 220.8 0.9 2.4 2 0 0 2 2 2 2 Septin AAA_22 PF13401.6 CAR27154.1 - 4.3e-05 23.8 0.1 0.00016 22.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 CAR27154.1 - 0.00055 20.1 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CAR27154.1 - 0.0015 18.3 0.1 0.0038 17.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 CAR27154.1 - 0.003 17.1 0.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 CAR27154.1 - 0.0033 17.9 0.0 0.012 16.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CAR27154.1 - 0.0072 16.3 0.1 0.056 13.3 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CAR27154.1 - 0.0073 16.7 0.6 0.05 14.0 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA PF00004.29 CAR27154.1 - 0.01 16.3 0.4 0.023 15.1 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CAR27154.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CAR27154.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Synaptobrevin PF00957.21 CAR27154.1 - 0.022 14.6 1.2 0.066 13.0 1.2 1.8 1 0 0 1 1 1 0 Synaptobrevin T2SSE PF00437.20 CAR27154.1 - 0.037 13.1 0.5 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.6 CAR27154.1 - 0.039 14.2 0.3 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF5545 PF17699.1 CAR27154.1 - 0.058 13.2 0.2 33 4.2 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5545) Mg_chelatase PF01078.21 CAR27154.1 - 0.066 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CAR27154.1 - 0.08 12.9 0.1 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CAR27154.1 - 0.099 12.6 0.0 0.26 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.23 CAR27154.1 - 0.13 12.4 1.7 0.28 11.2 0.0 2.4 3 1 0 3 3 3 0 Dynamin family DUF87 PF01935.17 CAR27154.1 - 2.1 8.4 5.4 19 5.2 0.0 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain YjeF_N PF03853.15 CAR27156.1 - 3.7e-34 118.1 0.0 4.8e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SMK-1 PF04802.15 CAR27157.1 - 2.1e-62 210.3 4.8 5.5e-60 202.5 1.8 2.5 2 0 0 2 2 2 2 Component of IIS longevity pathway SMK-1 adh_short_C2 PF13561.6 CAR27158.1 - 1.4e-47 162.2 0.1 1.7e-47 161.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR27158.1 - 9.6e-38 129.6 0.2 1.2e-37 129.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR27158.1 - 1.1e-11 45.0 0.3 1.9e-11 44.2 0.3 1.3 1 0 0 1 1 1 1 KR domain ArfGap PF01412.18 CAR27159.1 - 7.7e-32 109.8 0.0 1.8e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH_18 PF18469.1 CAR27160.1 - 4.5e-51 172.5 0.6 1.3e-50 171.1 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Rtt106 PF08512.12 CAR27160.1 - 5.9e-31 106.7 0.6 1.2e-30 105.8 0.6 1.5 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Rtt106_N PF18215.1 CAR27160.1 - 1.3e-06 28.0 0.1 2.9e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Histone chaperone Rtt106 N-terminal domain RIO1 PF01163.22 CAR27161.1 - 7.6e-41 139.8 0.1 1.4e-40 138.9 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CAR27161.1 - 1.2e-31 108.7 0.1 5.6e-31 106.6 0.1 2.1 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 CAR27161.1 - 3.2e-08 33.8 0.0 3.8e-05 23.7 0.0 3.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CAR27161.1 - 0.021 14.2 0.2 1.1 8.5 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CAR27161.1 - 0.042 12.6 0.0 0.042 12.6 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase YlbD_coat PF14071.6 CAR27161.1 - 0.13 12.5 3.0 0.28 11.5 3.0 1.6 1 0 0 1 1 1 0 Putative coat protein MFMR_assoc PF16596.5 CAR27161.1 - 2.7 8.4 6.6 5 7.6 6.6 1.4 1 0 0 1 1 1 0 Disordered region downstream of MFMR DNA_pol_phi PF04931.13 CAR27161.1 - 9.1 4.2 12.8 12 3.8 12.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi E6 PF00518.17 CAR27162.1 - 2e-06 28.2 0.5 2.7e-06 27.8 0.5 1.2 1 0 0 1 1 1 1 Early Protein (E6) Cytochrome_C7 PF14522.6 CAR27162.1 - 0.00034 20.6 1.3 0.00047 20.1 1.3 1.5 1 1 0 1 1 1 1 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 CAR27162.1 - 0.0071 16.8 0.9 0.0071 16.8 0.9 1.7 2 0 0 2 2 2 1 Cytochrome c3 Cytochrom_NNT PF03264.14 CAR27162.1 - 0.014 15.1 1.3 0.024 14.4 1.3 1.3 1 0 0 1 1 1 0 NapC/NirT cytochrome c family, N-terminal region DZR PF12773.7 CAR27162.1 - 0.016 15.2 1.1 0.029 14.4 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon Paired_CXXCH_1 PF09699.10 CAR27162.1 - 0.026 14.3 1.2 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF3365 PF11845.8 CAR27162.1 - 0.042 14.2 3.0 0.74 10.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3365) zf-CHY PF05495.12 CAR27162.1 - 0.045 14.2 2.5 0.098 13.2 2.5 1.5 1 0 0 1 1 1 0 CHY zinc finger Cytochrom_CIII PF02085.16 CAR27162.1 - 0.31 11.4 5.2 0.14 12.5 1.8 2.0 2 1 0 2 2 2 0 Class III cytochrome C family PLATZ PF04640.14 CAR27162.1 - 0.73 10.5 4.9 4.6 7.9 0.5 2.3 1 1 1 2 2 2 0 PLATZ transcription factor Rick_17kDa_Anti PF05433.15 CAR27163.1 - 3.5e-06 26.8 10.9 3.5e-06 26.8 10.9 3.7 3 1 0 3 3 3 1 Glycine zipper 2TM domain Ribonuclease_T2 PF00445.18 CAR27164.1 - 1.2e-21 77.7 0.0 1.8e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Hom_end_hint PF05203.16 CAR27165.1 - 4.9e-60 203.3 0.0 5.8e-60 203.1 0.0 1.0 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.14 CAR27165.1 - 1.7e-45 153.7 0.0 4.7e-37 126.5 0.0 2.6 2 0 0 2 2 2 2 Homing endonuclease LAGLIDADG_3 PF14528.6 CAR27165.1 - 4.5e-09 36.5 0.0 2.1e-05 24.8 0.0 2.7 2 0 0 2 2 2 2 LAGLIDADG-like domain DUF1794 PF08768.11 CAR27165.1 - 0.12 12.3 0.4 0.89 9.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1794) FdhE PF04216.12 CAR27165.1 - 0.52 10.1 4.9 0.85 9.4 4.9 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation HSP70 PF00012.20 CAR27166.1 - 5.9e-227 754.6 9.5 6.7e-227 754.4 9.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR27166.1 - 2.1e-17 62.9 0.4 7.6e-16 57.8 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CAR27166.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CAR27166.1 - 0.087 13.3 4.3 9.5 6.7 0.1 3.6 3 2 0 3 3 3 0 Cell division protein FtsA DUF883 PF05957.13 CAR27166.1 - 7 7.3 8.9 5.7 7.6 1.3 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) KH_1 PF00013.29 CAR27167.1 - 1.1e-08 34.8 0.0 4.1e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 KH domain KH_2 PF07650.17 CAR27167.1 - 0.00092 19.0 0.0 0.0055 16.5 0.1 2.2 2 0 0 2 2 2 1 KH domain Y_phosphatase PF00102.27 CAR27168.1 - 2.3e-55 187.7 0.8 2.5e-54 184.4 0.8 2.1 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CAR27168.1 - 0.00016 21.5 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CAR27168.1 - 0.014 15.3 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 CAR27168.1 - 0.079 13.1 0.0 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate ArAE_2 PF10334.9 CAR27169.1 - 1.1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 CAR27169.1 - 6.1e-06 26.4 24.2 1.7e-05 24.9 9.4 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 CAR27169.1 - 0.00087 18.4 2.7 0.00087 18.4 2.7 2.9 3 0 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal DUF2379 PF09543.10 CAR27169.1 - 0.0026 17.9 0.1 14 5.9 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2379) DUF2951 PF11166.8 CAR27169.1 - 0.023 14.9 2.5 0.15 12.3 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) SpoVIF PF14069.6 CAR27169.1 - 0.061 13.1 0.2 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Stage VI sporulation protein F Mrx7 PF10906.8 CAR27170.1 - 3.7e-30 104.0 0.1 4.5e-30 103.7 0.1 1.1 1 0 0 1 1 1 1 MIOREX complex component 7 VID27 PF08553.10 CAR27171.1 - 2.7e-156 520.1 1.4 3.9e-156 519.6 1.4 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 CAR27171.1 - 3.8e-42 144.0 0.9 3.8e-42 144.0 0.9 3.0 3 0 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 CAR27171.1 - 3.1e-28 98.2 1.2 6.1e-27 94.1 0.1 3.2 2 1 0 3 3 3 1 VID27 PH-like domain WD40 PF00400.32 CAR27171.1 - 0.09 13.7 0.1 6.4 7.8 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat PAZ_siRNAbind PF12212.8 CAR27171.1 - 0.091 12.6 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 PAZ domain DUF2052 PF09747.9 CAR27171.1 - 6.7 6.8 21.5 0.015 15.5 4.9 2.6 2 1 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) PI3K_1B_p101 PF10486.9 CAR27171.1 - 7.1 4.3 9.4 6 4.5 4.2 2.2 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Neugrin PF06413.11 CAR27172.1 - 8.8e-07 29.2 1.6 8.8e-07 29.2 1.6 1.8 1 1 0 1 1 1 1 Neugrin Integrase_Zn PF02022.19 CAR27172.1 - 0.018 15.0 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain Sigma70_r4 PF04545.16 CAR27172.1 - 0.019 14.4 0.1 0.041 13.4 0.1 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 LIM_bind PF01803.16 CAR27174.1 - 2.4e-43 148.4 1.4 4e-43 147.7 1.4 1.3 1 0 0 1 1 1 1 LIM-domain binding protein HIM1 PF08732.10 CAR27174.1 - 0.017 14.6 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 HIM1 PAPA-1 PF04795.12 CAR27175.1 - 7.9e-19 68.2 19.4 5e-18 65.7 7.1 2.6 2 0 0 2 2 2 2 PAPA-1-like conserved region Spem1 PF15670.5 CAR27175.1 - 2.8 7.4 7.7 0.71 9.4 2.3 2.1 2 0 0 2 2 2 0 Spermatid maturation protein 1 RabGAP-TBC PF00566.18 CAR27176.1 - 5.8e-35 120.9 16.0 3.6e-32 111.8 7.7 2.6 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PH_RBD PF12068.8 CAR27176.1 - 7.4e-06 25.5 0.3 0.00012 21.6 0.0 2.3 2 0 0 2 2 2 1 Rab-binding domain (RBD) Rap1-DNA-bind PF09197.10 CAR27177.1 - 3.4e-46 156.3 9.3 4.4e-45 152.7 0.1 3.4 2 1 0 2 2 2 1 Rap1, DNA-binding Rap1_C PF11626.8 CAR27177.1 - 2.2e-21 75.7 1.8 4.4e-21 74.8 0.0 2.6 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 CAR27177.1 - 2.2e-17 63.2 0.0 1.2e-16 60.9 0.0 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-binding PF00249.31 CAR27177.1 - 5.1e-14 52.2 0.0 1.4e-10 41.2 0.0 3.9 4 0 0 4 4 4 1 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 CAR27177.1 - 2.3e-09 37.3 0.5 5.1e-05 23.4 0.1 2.9 2 0 0 2 2 2 2 Rap1 Myb domain SLIDE PF09111.10 CAR27177.1 - 0.2 11.7 3.9 0.27 11.3 0.0 3.2 4 0 0 4 4 4 0 SLIDE Tic110 PF16940.5 CAR27177.1 - 1.9 6.8 4.2 3.6 6.0 4.2 1.3 1 0 0 1 1 1 0 Chloroplast envelope transporter FAD_binding_2 PF00890.24 CAR27178.1 - 4.7e-122 408.1 2.2 6.2e-122 407.7 2.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CAR27178.1 - 5.5e-44 149.3 2.3 8.5e-44 148.6 2.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 CAR27178.1 - 5.3e-05 22.6 0.5 0.00025 20.4 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CAR27178.1 - 0.00016 21.1 3.2 0.0038 16.5 0.1 3.0 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 CAR27178.1 - 0.00051 19.2 5.7 0.007 15.5 1.9 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.17 CAR27178.1 - 0.0035 16.6 0.2 0.045 13.0 0.1 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 CAR27178.1 - 0.033 12.9 0.0 0.22 10.2 0.0 2.4 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 CAR27178.1 - 0.052 13.1 3.0 0.15 11.6 3.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAR27178.1 - 0.07 13.4 1.2 0.75 10.1 0.4 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CAR27178.1 - 0.59 9.3 2.1 7.4 5.7 0.9 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DBR1 PF05011.13 CAR27179.1 - 6.4e-11 42.8 0.1 1.1e-10 42.1 0.1 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CAR27179.1 - 1.8e-08 35.2 2.9 3.3e-08 34.3 2.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAD_binding_6 PF00970.24 CAR27180.1 - 3.1e-28 98.0 0.0 4.6e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CAR27180.1 - 1.6e-27 96.3 0.0 2.5e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CAR27180.1 - 1.8e-07 31.4 0.0 0.00016 21.8 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Carb_kinase PF01256.17 CAR27181.1 - 4.2e-67 226.2 0.0 6.5e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 CAR27181.1 - 0.019 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase His_Phos_1 PF00300.22 CAR27182.1 - 1.2e-37 129.5 0.0 4.1e-30 104.9 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Tnp_22_dsRBD PF17490.2 CAR27182.1 - 0.057 13.4 0.1 0.17 11.9 0.0 1.8 1 1 0 1 1 1 0 L1 transposable element dsRBD-like domain RabGAP-TBC PF00566.18 CAR27183.1 - 1.8e-17 63.7 0.3 2.6e-17 63.2 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Interferon PF00143.19 CAR27183.1 - 0.086 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Interferon alpha/beta domain LRR_4 PF12799.7 CAR27184.1 - 6 7.4 7.9 13 6.4 0.4 4.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Nsp1_C PF05064.13 CAR27185.1 - 3.5e-40 136.4 3.4 3.5e-40 136.4 3.4 2.0 1 1 1 2 2 2 1 Nsp1-like C-terminal region Laminin_II PF06009.12 CAR27185.1 - 0.017 15.1 11.0 3.1 7.8 6.9 2.9 1 1 2 3 3 3 0 Laminin Domain II APG6_N PF17675.1 CAR27185.1 - 0.45 11.0 9.5 1.5 9.4 9.5 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF87 PF01935.17 CAR27185.1 - 1.5 8.9 5.9 3.6 7.6 5.9 1.6 1 1 0 1 1 1 0 Helicase HerA, central domain CLZ PF16526.5 CAR27185.1 - 2.7 8.4 4.5 4.3 7.8 0.8 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF16 PF01519.16 CAR27185.1 - 3.9 8.0 6.3 1.3 9.5 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Nup192 PF11894.8 CAR27186.1 - 0 1730.1 61.9 0 1729.9 61.9 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 S-layer PF07752.11 CAR27186.1 - 0.01 14.9 1.9 0.021 13.9 0.6 2.2 2 0 0 2 2 2 0 S-layer protein DPM2 PF07297.12 CAR27187.1 - 1.1e-10 41.6 2.5 1.3e-10 41.5 2.5 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 CAR27187.1 - 0.0078 16.1 2.3 0.0088 16.0 2.3 1.1 1 0 0 1 1 1 1 PIG-P SRPRB PF09439.10 CAR27188.1 - 1.9e-62 209.9 0.0 2.6e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CAR27188.1 - 6.9e-07 28.9 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR27188.1 - 1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR27188.1 - 9.6e-05 22.4 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 CAR27188.1 - 0.05 14.1 1.7 0.12 12.8 1.7 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAR27188.1 - 0.17 11.7 0.1 0.36 10.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rsm22 PF09243.10 CAR27189.1 - 1.5e-31 109.7 0.8 6.2e-12 45.4 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 CAR27189.1 - 5.9e-07 29.5 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain P22_Cro PF14549.6 CAR27189.1 - 0.14 12.0 0.1 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro Ribosomal_S27e PF01667.17 CAR27190.1 - 3.1e-30 103.7 2.8 4e-30 103.3 2.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.21 CAR27190.1 - 0.005 17.0 0.9 0.0064 16.7 0.9 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 CAR27190.1 - 0.023 14.2 4.2 0.035 13.6 4.2 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding zf-ACC PF17848.1 CAR27190.1 - 3.2 7.9 6.4 19 5.4 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Myosin_head PF00063.21 CAR27191.1 - 4e-264 878.0 11.4 4e-264 878.0 11.4 3.5 5 1 0 5 5 5 1 Myosin head (motor domain) GAS PF13851.6 CAR27191.1 - 0.0041 16.5 14.6 0.0041 16.5 14.6 11.3 1 1 8 11 11 11 5 Growth-arrest specific micro-tubule binding Myosin_N PF02736.19 CAR27191.1 - 0.031 14.1 0.8 0.084 12.7 0.8 1.7 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 CAR27191.1 - 0.2 12.0 0.0 0.2 12.0 0.0 4.2 4 3 0 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 CAR27191.1 - 0.27 11.5 0.0 0.27 11.5 0.0 5.4 6 1 0 6 6 6 0 AAA domain Peptidase_M16_C PF05193.21 CAR27192.1 - 3.8e-46 157.4 0.0 1.3e-45 155.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CAR27192.1 - 1.4e-45 154.9 0.0 7.4e-44 149.3 0.0 2.3 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) XPG_N PF00752.17 CAR27193.1 - 8.8e-29 100.0 0.0 1.7e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CAR27193.1 - 3.1e-21 75.5 0.0 7.6e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CAR27193.1 - 4.5e-05 24.0 0.0 0.00012 22.6 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 CAR27193.1 - 0.00023 21.2 0.0 0.014 15.5 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix motif XPG_I_2 PF12813.7 CAR27193.1 - 0.0038 16.7 0.0 0.0077 15.7 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing DHHC PF01529.20 CAR27194.1 - 1.4e-25 90.0 5.2 1.4e-25 90.0 5.2 2.9 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CAR27194.1 - 2.6e-22 79.2 0.0 4.4e-06 27.2 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAR27194.1 - 1.4e-20 73.3 0.1 5.8e-07 30.0 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAR27194.1 - 9.7e-19 65.5 0.3 0.0014 18.9 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CAR27194.1 - 3.2e-18 65.5 0.2 1.4e-05 25.2 0.0 4.8 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CAR27194.1 - 1.2e-13 50.8 0.0 0.00013 22.2 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat UNC45-central PF11701.8 CAR27195.1 - 1.2e-27 96.8 4.2 1.2e-27 96.8 4.2 3.4 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central DED PF01335.21 CAR27195.1 - 0.13 12.6 6.4 1.4 9.3 0.7 4.4 3 1 0 3 3 3 0 Death effector domain Pex2_Pex12 PF04757.14 CAR27196.1 - 1.9e-36 125.8 4.7 4.5e-36 124.5 4.7 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 CAR27196.1 - 1.2e-08 35.2 17.6 1.9e-08 34.5 17.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CAR27196.1 - 1.1e-06 28.4 17.4 1.7e-06 27.8 17.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR27196.1 - 2e-06 27.6 16.7 3.4e-06 26.8 16.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR27196.1 - 6.7e-06 25.8 17.0 1.1e-05 25.1 17.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR27196.1 - 2e-05 24.3 16.2 3.2e-05 23.7 16.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CAR27196.1 - 9.7e-05 22.3 13.5 0.00027 20.9 13.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CAR27196.1 - 0.0013 19.0 15.2 0.0034 17.6 15.2 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CAR27196.1 - 0.003 17.7 17.0 0.0063 16.7 17.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CAR27196.1 - 0.0035 17.3 13.0 0.0071 16.3 13.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Neural_ProG_Cyt PF06567.11 CAR27196.1 - 0.076 13.2 0.3 0.22 11.8 0.0 1.8 2 0 0 2 2 2 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain zf-RING_11 PF17123.5 CAR27196.1 - 0.37 10.6 7.4 0.95 9.3 7.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 CAR27197.1 - 9.7e-10 38.2 9.1 9.7e-10 38.2 9.1 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR27197.1 - 0.0015 18.3 10.3 0.0015 18.3 10.3 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR27197.1 - 0.0026 17.6 8.4 0.0026 17.6 8.4 3.0 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CAR27197.1 - 7.9 6.4 29.4 0.024 14.5 11.1 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Syntaxin_2 PF14523.6 CAR27198.1 - 9e-21 74.2 15.5 6e-20 71.5 7.7 2.3 2 0 0 2 2 2 2 Syntaxin-like protein SNARE PF05739.19 CAR27198.1 - 2.8e-13 49.6 3.7 1.9e-12 47.0 3.7 2.4 1 1 0 1 1 1 1 SNARE domain CEP209_CC5 PF16574.5 CAR27198.1 - 0.0035 17.5 0.8 0.0035 17.5 0.8 3.0 1 1 1 2 2 2 1 Coiled-coil region of centrosome protein CE290 ThrE PF06738.12 CAR27198.1 - 0.011 15.1 0.5 0.029 13.7 0.1 1.8 1 1 1 2 2 2 0 Putative threonine/serine exporter Syntaxin PF00804.25 CAR27198.1 - 0.47 10.1 21.7 0.1 12.2 16.0 2.8 2 1 0 2 2 2 0 Syntaxin DUF722 PF05263.11 CAR27198.1 - 1 9.6 7.0 1.7 8.9 1.2 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF722) WD40 PF00400.32 CAR27199.1 - 1e-38 130.6 22.2 1.2e-08 35.4 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27199.1 - 6.9e-14 51.9 9.8 0.00071 19.8 0.1 6.0 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CAR27199.1 - 0.0051 15.9 7.3 0.1 11.6 0.9 3.1 2 1 1 3 3 3 2 Coatomer WD associated region CRT10 PF08728.10 CAR27199.1 - 0.051 11.7 1.4 0.19 9.9 0.0 2.4 3 1 0 4 4 4 0 CRT10 FAD_binding_6 PF00970.24 CAR27200.1 - 1.6e-07 31.6 0.0 6.2e-05 23.3 0.0 2.9 2 1 1 3 3 3 2 Oxidoreductase FAD-binding domain tRNA-synt_1b PF00579.25 CAR27201.1 - 2.6e-78 263.3 0.2 3.3e-78 263.0 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NCD1 PF04904.13 CAR27201.1 - 0.14 12.2 0.1 16 5.5 0.0 2.4 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) Hira PF07569.11 CAR27202.1 - 5.8e-88 294.3 5.2 1e-87 293.5 0.0 3.5 4 0 0 4 4 4 1 TUP1-like enhancer of split WD40 PF00400.32 CAR27202.1 - 0.0097 16.7 3.7 3.4 8.7 0.0 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Topoisom_bac PF01131.20 CAR27202.1 - 0.02 13.9 0.2 0.033 13.2 0.2 1.3 1 0 0 1 1 1 0 DNA topoisomerase ANAPC4_WD40 PF12894.7 CAR27202.1 - 0.098 13.0 0.0 1.7 9.0 0.0 3.0 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CK_II_beta PF01214.18 CAR27203.1 - 5.4e-72 241.4 0.0 6.7e-72 241.1 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit AAA-ATPase_like PF09820.9 CAR27203.1 - 0.03 13.7 0.1 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase E1-E2_ATPase PF00122.20 CAR27204.1 - 7.8e-48 162.4 0.2 5.7e-47 159.6 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CAR27204.1 - 1.6e-33 116.8 0.0 2.9e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CAR27204.1 - 9.7e-31 106.0 11.9 3.3e-16 59.5 1.5 2.6 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CAR27204.1 - 2.8e-06 27.2 0.1 0.05 13.3 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Herpes_UL31 PF02718.14 CAR27204.1 - 0.049 12.6 0.1 0.13 11.2 0.1 1.6 1 0 0 1 1 1 0 Herpesvirus UL31-like protein DUF211 PF02680.14 CAR27204.1 - 0.05 13.8 3.4 0.09 12.9 1.4 2.4 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 HAD PF12710.7 CAR27204.1 - 0.12 12.8 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FliM PF02154.15 CAR27204.1 - 0.16 11.9 0.0 0.46 10.3 0.0 1.7 2 0 0 2 2 2 0 Flagellar motor switch protein FliM Spore_YhcN_YlaJ PF09580.10 CAR27204.1 - 0.59 10.2 7.5 18 5.4 0.1 3.5 4 0 0 4 4 4 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) HAGH_C PF16123.5 CAR27205.1 - 2.1e-17 63.4 0.2 3.7e-17 62.6 0.2 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CAR27205.1 - 4.5e-09 36.6 0.2 1.4e-08 35.0 0.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CAR27205.1 - 0.04 13.4 0.2 0.079 12.5 0.2 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain CUE PF02845.16 CAR27206.1 - 1.4e-09 37.4 0.0 2.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain SDA1 PF05285.12 CAR27207.1 - 2.9e-97 326.2 42.9 2.9e-97 326.2 42.9 2.9 3 0 0 3 3 3 1 SDA1 NUC130_3NT PF08158.12 CAR27207.1 - 1.3e-20 73.5 0.5 1.3e-20 73.5 0.5 2.1 2 0 0 2 2 2 1 NUC130/3NT domain TINF2_N PF14973.6 CAR27207.1 - 0.028 14.8 3.2 0.081 13.3 0.4 3.0 3 0 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus Trans_reg_C PF00486.28 CAR27207.1 - 0.15 12.2 4.1 0.23 11.5 0.2 3.1 4 0 0 4 4 4 0 Transcriptional regulatory protein, C terminal TFIIB PF00382.19 CAR27208.1 - 5.8e-57 189.7 1.0 1.1e-28 99.1 0.2 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CAR27208.1 - 3.9e-29 101.0 2.7 3.9e-29 101.0 2.7 2.9 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CAR27208.1 - 2.2e-12 46.3 2.9 4.6e-12 45.2 2.9 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 CAR27208.1 - 0.00024 20.9 0.2 0.094 12.5 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain RNA_polI_A14 PF08203.11 CAR27208.1 - 0.22 12.3 2.9 1.2 9.9 0.1 3.0 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 TLP-20 PF06088.11 CAR27208.1 - 3.5 7.5 9.6 0.077 12.9 1.3 2.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CPDase PF07823.11 CAR27209.1 - 3.3e-80 268.5 0.2 3.7e-80 268.3 0.2 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 CAR27209.1 - 5.7e-05 23.1 0.1 0.046 13.6 0.1 2.2 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily DUF2070 PF09843.9 CAR27209.1 - 0.024 13.0 0.0 0.031 12.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) LigT_PEase PF02834.16 CAR27209.1 - 0.11 12.6 0.0 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 LigT like Phosphoesterase Glucosamine_iso PF01182.20 CAR27210.1 - 2.2e-59 201.1 0.0 2.4e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HSF_DNA-bind PF00447.17 CAR27211.1 - 6.2e-22 78.0 0.0 9.9e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Spt46 PF17734.1 CAR27211.1 - 0.17 11.6 0.7 1.1 9.0 0.3 2.1 2 0 0 2 2 2 0 Spermatogenesis-associated protein 46 Dna2 PF08696.11 CAR27212.1 - 3.3e-54 183.8 0.1 1.1e-53 182.1 0.1 2.0 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 CAR27212.1 - 8.9e-50 169.1 0.3 2.2e-49 167.8 0.3 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAR27212.1 - 1e-25 91.0 0.0 7.3e-14 52.2 0.0 3.6 3 1 1 4 4 3 2 AAA domain AAA_30 PF13604.6 CAR27212.1 - 3.9e-14 52.8 0.0 9e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR27212.1 - 1.5e-10 41.6 0.0 3.3e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.7 CAR27212.1 - 5.8e-08 33.0 0.0 1.1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 CAR27212.1 - 2.7e-07 30.6 0.4 0.13 12.0 0.0 3.8 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Csa1 PF06023.12 CAR27212.1 - 0.00024 20.5 0.3 0.00059 19.3 0.0 1.7 2 0 0 2 2 2 1 CRISPR-associated exonuclease Csa1 SRP54 PF00448.22 CAR27212.1 - 0.0018 17.9 0.1 0.0042 16.7 0.1 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Cas_Cas4 PF01930.17 CAR27212.1 - 0.0066 16.6 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF83 CbiA PF01656.23 CAR27212.1 - 0.0075 16.3 0.1 0.043 13.9 0.0 2.3 2 0 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 CAR27212.1 - 0.0077 16.1 0.2 0.017 15.0 0.2 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 CAR27212.1 - 0.011 15.4 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CAR27212.1 - 0.013 15.9 0.0 0.038 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.17 CAR27212.1 - 0.016 15.0 0.1 0.059 13.1 0.1 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 CAR27212.1 - 0.018 14.0 0.1 0.033 13.2 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 CAR27212.1 - 0.022 14.7 0.1 0.049 13.6 0.1 1.6 1 0 0 1 1 1 0 NTPase Helicase_RecD PF05127.14 CAR27212.1 - 0.023 14.5 0.0 0.092 12.6 0.0 2.1 1 1 0 1 1 1 0 Helicase TrwB_AAD_bind PF10412.9 CAR27212.1 - 0.029 13.3 0.3 0.12 11.2 0.1 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.14 CAR27212.1 - 0.032 13.4 0.0 0.47 9.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase NB-ARC PF00931.22 CAR27212.1 - 0.041 13.1 0.4 0.13 11.4 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 CAR27212.1 - 0.043 14.2 0.1 0.38 11.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CAR27212.1 - 0.054 13.7 0.0 0.43 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CAR27212.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CAR27212.1 - 0.063 13.8 0.0 0.41 11.2 0.0 2.4 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 CAR27212.1 - 0.085 12.9 0.5 0.28 11.2 0.0 2.2 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CAR27212.1 - 0.1 12.1 0.0 0.1 12.1 0.0 3.0 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain AAA_18 PF13238.6 CAR27212.1 - 0.1 13.2 0.0 0.67 10.5 0.0 2.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CAR27212.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArsA_ATPase PF02374.15 CAR27212.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.9 2 0 0 2 2 1 0 Anion-transporting ATPase FAM219A PF15260.6 CAR27212.1 - 0.14 12.5 0.0 0.14 12.5 0.0 2.4 2 0 0 2 2 1 0 Protein family FAM219A Mg_chelatase PF01078.21 CAR27212.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_31 PF13614.6 CAR27212.1 - 1.2 9.0 4.4 2 8.3 1.1 2.9 2 1 0 2 2 2 0 AAA domain DUF240 PF03086.14 CAR27213.1 - 0.062 13.2 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF240) PROCN PF08083.11 CAR27214.1 - 4.3e-219 727.2 12.3 6.6e-219 726.6 12.3 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CAR27214.1 - 1.7e-122 407.4 0.6 3.7e-122 406.3 0.6 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CAR27214.1 - 7.8e-84 279.4 1.1 7.8e-84 279.4 1.1 2.0 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CAR27214.1 - 6.1e-81 269.7 2.3 1.4e-80 268.6 2.3 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CAR27214.1 - 2.9e-68 228.1 0.0 5.8e-68 227.1 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 CAR27214.1 - 9.2e-47 158.0 0.0 1.9e-46 157.0 0.0 1.6 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 CAR27214.1 - 2.8e-45 152.6 0.5 6.9e-45 151.3 0.5 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 ANAPC8 PF04049.13 CAR27215.1 - 1.8e-38 131.8 2.1 9.2e-38 129.5 0.2 2.6 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 CAR27215.1 - 4.5e-19 67.4 27.2 4.1e-06 26.4 0.8 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 CAR27215.1 - 1.3e-18 65.5 23.4 0.00022 21.2 0.0 8.7 9 2 1 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 CAR27215.1 - 1.6e-16 59.0 27.7 9e-06 25.4 1.0 8.7 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 CAR27215.1 - 2e-10 40.6 16.6 0.0015 19.2 1.4 5.8 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAR27215.1 - 2.9e-09 36.5 12.2 2.3e-07 30.4 0.1 4.4 3 2 2 5 5 4 2 TPR repeat TPR_16 PF13432.6 CAR27215.1 - 1.3e-08 35.3 5.9 9.6e-05 23.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAR27215.1 - 3.2e-08 33.1 7.6 4.4e-05 23.2 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR27215.1 - 1.8e-07 31.3 17.3 0.00012 22.3 2.5 5.4 3 2 2 6 6 6 2 Tetratricopeptide repeat ChAPs PF09295.10 CAR27215.1 - 2.7e-05 23.3 0.3 0.0048 16.0 0.0 2.1 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 CAR27215.1 - 4e-05 23.0 4.6 0.0049 16.1 1.5 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat RPN7 PF10602.9 CAR27215.1 - 6.5e-05 22.7 0.3 0.0006 19.6 0.7 2.4 2 0 0 2 2 2 1 26S proteasome subunit RPN7 ANAPC3 PF12895.7 CAR27215.1 - 7.4e-05 22.9 21.9 0.055 13.7 0.7 5.8 3 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 CAR27215.1 - 0.00011 22.6 0.7 0.00027 21.4 0.7 1.7 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_19 PF14559.6 CAR27215.1 - 0.00017 22.0 7.8 0.023 15.2 0.2 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR27215.1 - 0.00095 19.4 17.4 0.19 12.2 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAR27215.1 - 0.0012 19.0 1.9 0.23 11.7 0.8 2.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CAR27215.1 - 0.0019 18.0 12.3 0.29 11.0 0.4 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CAR27215.1 - 0.02 14.2 1.8 0.036 13.5 1.8 1.3 1 0 0 1 1 1 0 MalT-like TPR region Sel1 PF08238.12 CAR27215.1 - 0.06 14.1 7.6 24 5.8 0.1 5.7 6 0 0 6 6 5 0 Sel1 repeat DUF2106 PF09879.9 CAR27215.1 - 0.096 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) DUF3856 PF12968.7 CAR27215.1 - 0.11 12.6 0.7 2.3 8.3 0.1 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 CAR27215.1 - 0.22 11.6 9.1 1.3 9.1 0.6 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain NSF PF02071.20 CAR27215.1 - 2.7 9.1 6.7 47 5.4 0.1 4.8 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat THP2 PF09432.10 CAR27216.1 - 6.6e-57 191.1 4.8 6.6e-57 191.1 4.8 2.0 2 1 0 2 2 2 1 Tho complex subunit THP2 DUF2310 PF10071.9 CAR27216.1 - 0.003 16.9 4.5 0.35 10.1 0.2 2.3 2 0 0 2 2 2 2 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Glyco_hydro_65m PF03632.15 CAR27216.1 - 0.0087 14.9 2.4 0.013 14.3 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain P21-Arc PF04062.14 CAR27216.1 - 0.1 12.6 0.2 0.1 12.6 0.2 1.8 2 0 0 2 2 2 0 ARP2/3 complex ARPC3 (21 kDa) subunit DUF2205 PF10224.9 CAR27216.1 - 0.32 11.0 11.6 0.081 12.9 1.5 3.5 3 1 1 4 4 4 0 Short coiled-coil protein DASH_Dam1 PF08653.10 CAR27216.1 - 0.7 9.7 0.1 0.7 9.7 0.1 3.1 5 0 0 5 5 5 0 DASH complex subunit Dam1 ApoA-II PF04711.13 CAR27216.1 - 1.7 8.8 8.5 0.62 10.3 2.0 2.7 3 0 0 3 3 3 0 Apolipoprotein A-II (ApoA-II) DUF349 PF03993.12 CAR27216.1 - 2.4 8.5 7.2 0.69 10.2 0.7 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) GTP1_OBG PF01018.22 CAR27217.1 - 6.6e-37 126.5 0.9 7.8e-28 97.0 1.0 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 CAR27217.1 - 4.4e-22 78.3 0.0 7.8e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR27217.1 - 1.1e-11 44.6 0.0 1.6e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 CAR27217.1 - 2.4e-09 36.9 0.0 6.1e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CAR27217.1 - 0.00085 18.9 0.0 0.0023 17.5 0.0 1.7 2 0 0 2 2 2 1 Ras family SRPRB PF09439.10 CAR27217.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CAR27217.1 - 0.0065 16.0 0.1 0.27 10.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CAR27217.1 - 0.017 15.2 0.2 4.7 7.2 0.1 2.6 2 1 1 3 3 3 0 Dynamin family MMR_HSR1_Xtn PF16897.5 CAR27217.1 - 0.061 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 CAR27217.1 - 0.16 11.8 0.1 15 5.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase MeaB PF03308.16 CAR27217.1 - 0.19 10.7 0.1 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DEAD PF00270.29 CAR27218.1 - 4e-39 134.2 0.0 8.8e-39 133.1 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR27218.1 - 6.9e-30 103.6 0.0 3.6e-29 101.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR27218.1 - 0.0063 16.5 0.1 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAR27218.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase NOP19 PF10863.8 CAR27219.1 - 2e-47 160.6 7.9 2e-47 160.6 7.9 1.8 2 0 0 2 2 2 1 Nucleolar protein 19 NMD3 PF04981.13 CAR27220.1 - 1.6e-82 276.7 1.5 2.5e-82 276.0 1.5 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 CAR27220.1 - 0.53 10.4 6.1 0.97 9.5 2.6 2.6 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 CAR27220.1 - 0.56 10.2 4.6 15 5.6 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ThiF PF00899.21 CAR27221.1 - 2.4e-51 174.5 0.0 3.7e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 CAR27221.1 - 1.3e-47 162.9 0.1 7.3e-47 160.5 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 CAR27221.1 - 0.0014 18.7 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CAR27221.1 - 0.075 12.4 0.0 0.66 9.3 0.0 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CAR27221.1 - 0.21 11.2 0.0 0.51 10.0 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Bromodomain PF00439.25 CAR27222.1 - 3.9e-26 90.9 2.5 8.4e-26 89.9 2.5 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CAR27222.1 - 1.1e-08 35.3 0.1 2.3e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR27222.1 - 2e-05 24.5 0.1 5.3e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR27222.1 - 0.0015 18.9 0.1 0.0028 18.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 CAR27222.1 - 1.1 8.6 4.3 6.7 6.0 0.0 2.3 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Proteasome PF00227.26 CAR27223.1 - 3.4e-53 180.0 0.0 4.5e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR27223.1 - 2.1e-12 46.5 0.0 5.3e-12 45.2 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 CAR27224.1 - 3e-39 135.5 0.4 3e-39 135.5 0.4 2.3 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CAR27224.1 - 2.3e-18 66.7 10.1 2.3e-18 66.7 10.1 1.9 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal Enolase_C PF00113.22 CAR27225.1 - 2.1e-147 490.1 0.0 2.8e-147 489.7 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CAR27225.1 - 1.1e-56 190.6 0.0 1.9e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CAR27225.1 - 1.1e-06 28.4 0.0 2.2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CAR27225.1 - 0.02 14.1 0.0 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Ctr PF04145.15 CAR27226.1 - 8.1e-23 81.7 11.7 4.8e-20 72.7 11.7 2.1 1 1 0 1 1 1 1 Ctr copper transporter family FMO-like PF00743.19 CAR27227.1 - 9.3e-43 146.4 0.0 1.3e-31 109.7 0.0 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CAR27227.1 - 2.7e-16 59.7 0.0 6.7e-15 55.1 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CAR27227.1 - 2.4e-14 53.3 0.0 8.4e-14 51.5 0.0 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAR27227.1 - 1.5e-13 51.0 0.0 1.2e-12 48.1 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 CAR27227.1 - 1.8e-10 40.5 0.8 0.0014 17.8 0.1 3.6 2 1 2 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CAR27227.1 - 5.1e-07 29.8 0.0 2.6e-06 27.6 0.0 2.2 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CAR27227.1 - 6e-07 29.4 0.0 0.034 13.7 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 CAR27227.1 - 1.3e-05 24.6 0.0 7.9e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Mqo PF06039.15 CAR27227.1 - 0.0022 16.6 0.1 0.0046 15.6 0.1 1.4 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Amino_oxidase PF01593.24 CAR27227.1 - 0.0069 15.7 0.0 0.083 12.2 0.0 2.3 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CAR27227.1 - 0.007 15.1 0.0 0.16 10.6 0.0 2.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 CAR27227.1 - 0.025 15.1 0.2 27 5.4 0.0 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CAR27227.1 - 0.047 14.1 0.0 4.4 7.8 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CAR27227.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CAR27227.1 - 0.21 10.6 0.0 0.59 9.1 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Fungal_trans PF04082.18 CAR27228.1 - 3.6e-24 85.2 0.5 5.6e-24 84.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR27228.1 - 5.3e-07 29.7 12.3 9e-07 28.9 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_FMN PF00724.20 CAR27229.1 - 6.2e-124 413.7 0.0 7.1e-124 413.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF5442 PF17514.2 CAR27229.1 - 0.14 12.3 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5442) Oxidored_FMN PF00724.20 CAR27230.1 - 8.9e-99 331.0 0.0 1.2e-98 330.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Ribosom_S12_S23 PF00164.25 CAR27231.1 - 6.7e-32 109.5 0.6 8.7e-32 109.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 PP2C PF00481.21 CAR27232.1 - 7.2e-29 101.2 0.0 3.5e-28 98.9 0.0 2.0 1 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 CAR27232.1 - 4.8e-05 23.1 0.0 0.00038 20.2 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 CAR27232.1 - 0.028 14.3 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) baeRF_family7 PF18849.1 CAR27232.1 - 0.046 13.9 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 DUF2689 PF10894.8 CAR27232.1 - 0.11 12.3 0.2 1.4 8.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2689) Ribosomal_S19 PF00203.21 CAR27233.1 - 4.6e-25 87.3 0.0 5.6e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Peptidase_M60_C PF18630.1 CAR27233.1 - 0.12 12.6 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase M60 C-terminal domain DEAD PF00270.29 CAR27234.1 - 1.6e-40 138.8 0.3 2.8e-40 137.9 0.3 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR27234.1 - 2e-21 76.4 1.0 4.7e-21 75.2 0.1 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR27234.1 - 9.7e-09 35.5 0.1 9.7e-09 35.5 0.1 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAR27234.1 - 0.09 13.0 1.8 0.93 9.8 1.8 2.6 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.14 CAR27234.1 - 0.095 12.7 0.3 0.49 10.4 0.1 2.3 1 1 1 2 2 2 0 Flavivirus DEAD domain Peptidase_S64 PF08192.11 CAR27234.1 - 0.32 9.4 15.9 0.61 8.5 15.9 1.4 1 0 0 1 1 1 0 Peptidase family S64 MTBP_C PF14920.6 CAR27234.1 - 0.62 9.8 9.7 1.2 8.8 9.7 1.4 1 0 0 1 1 1 0 MDM2-binding CCDC106 PF15794.5 CAR27234.1 - 1.4 8.6 14.1 2.9 7.6 14.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 CAML PF14963.6 CAR27234.1 - 2.7 8.0 14.5 6.2 6.9 14.5 1.5 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand UvrD-helicase PF00580.21 CAR27234.1 - 7.8 5.9 17.8 0.21 11.1 0.2 2.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Med12 PF09497.10 CAR27235.1 - 9.8e-24 83.4 0.6 2.9e-23 81.9 0.6 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Myb_DNA-bind_6 PF13921.6 CAR27235.1 - 0.077 13.3 0.0 0.31 11.3 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain Cation_efflux PF01545.21 CAR27236.1 - 0.063 13.0 12.1 0.13 11.9 11.4 1.7 1 1 0 1 1 1 0 Cation efflux family Pkinase PF00069.25 CAR27237.1 - 3e-46 157.9 0.1 5.8e-46 157.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27237.1 - 8.6e-29 100.6 0.1 1.3e-28 100.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4299 PF14132.6 CAR27237.1 - 0.00064 19.2 0.9 0.001 18.6 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) APH PF01636.23 CAR27237.1 - 0.032 14.1 0.2 2.5 7.9 0.1 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S8 PF00410.19 CAR27238.1 - 1.9e-23 82.8 0.1 2.7e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.19 CAR27239.1 - 1.5e-45 154.1 1.8 1.9e-45 153.8 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 CAR27239.1 - 0.0073 15.6 0.4 0.0091 15.3 0.4 1.1 1 0 0 1 1 1 1 beta-keto acid cleavage enzyme SOP4 PF17081.5 CAR27240.1 - 2.6e-86 288.5 0.0 3e-86 288.3 0.0 1.0 1 0 0 1 1 1 1 Suppressor of PMA 1-7 protein Beach PF02138.18 CAR27241.1 - 2.4e-118 394.5 0.5 5.3e-118 393.4 0.5 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CAR27241.1 - 4.7e-11 42.7 0.1 1.7e-10 40.9 0.1 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH TPT PF03151.16 CAR27242.1 - 6e-31 107.9 17.6 9e-29 100.7 17.6 3.1 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CAR27242.1 - 0.022 15.0 36.5 0.042 14.0 12.7 4.1 2 2 1 3 3 3 0 EamA-like transporter family AAA_22 PF13401.6 CAR27243.1 - 4.4e-10 40.0 0.0 1.4e-09 38.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CAR27243.1 - 2.7e-09 37.5 0.6 2.2e-08 34.6 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 CAR27243.1 - 6.6e-09 35.6 0.1 2e-08 34.1 0.1 1.9 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_16 PF13191.6 CAR27243.1 - 1.2e-06 29.0 0.0 5e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 CAR27243.1 - 0.00078 19.0 0.4 0.56 9.7 0.0 2.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_19 PF13245.6 CAR27243.1 - 0.0011 19.3 1.0 0.013 15.8 0.1 2.9 2 2 1 3 3 3 1 AAA domain Rad17 PF03215.15 CAR27243.1 - 0.0036 17.2 0.1 0.026 14.5 0.0 2.3 2 1 1 3 3 3 1 Rad17 P-loop domain DUF2075 PF09848.9 CAR27243.1 - 0.004 16.4 0.2 0.0099 15.1 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 CAR27243.1 - 0.013 15.8 0.1 2 8.8 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_11 PF13086.6 CAR27243.1 - 0.019 14.8 0.3 0.18 11.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CAR27243.1 - 0.019 14.7 0.0 0.046 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CAR27243.1 - 0.06 13.1 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Myb_DNA-binding PF00249.31 CAR27244.1 - 4.3e-14 52.4 0.0 5.7e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR27244.1 - 5.6e-05 23.3 0.2 0.088 13.1 0.1 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain CALCOCO1 PF07888.11 CAR27245.1 - 5.6 5.7 33.9 30 3.3 33.9 1.9 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Nrap_D5 PF17406.2 CAR27246.1 - 5.2e-54 182.4 0.0 1e-53 181.4 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 CAR27246.1 - 2.6e-52 176.6 1.1 2.6e-49 166.9 0.9 2.8 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 CAR27246.1 - 3.9e-50 170.2 0.1 6.7e-50 169.4 0.1 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 CAR27246.1 - 2e-45 154.6 4.6 4.6e-45 153.4 4.6 1.7 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 CAR27246.1 - 7.9e-41 139.8 0.0 1.8e-40 138.7 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 CAR27246.1 - 2.6e-29 102.1 0.3 6.9e-29 100.8 0.3 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 Phage_C PF12025.8 CAR27246.1 - 0.26 11.2 1.5 0.87 9.5 0.1 2.6 3 0 0 3 3 3 0 Phage protein C FAM76 PF16046.5 CAR27246.1 - 1.4 8.2 4.5 2.2 7.6 4.5 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1746 PF08508.10 CAR27247.1 - 5.8e-05 23.4 3.3 0.009 16.4 3.3 3.0 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RNA_pol_A_bac PF01000.26 CAR27248.1 - 3.3e-29 101.5 0.0 8e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CAR27248.1 - 1.3e-20 72.6 0.0 1.9e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Nop PF01798.18 CAR27249.1 - 4.4e-63 212.8 0.1 6.9e-63 212.2 0.1 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CAR27249.1 - 1.2e-24 87.5 6.7 1.5e-24 87.2 5.6 1.7 2 0 0 2 2 2 1 Prp31 C terminal domain Endonuc-PvuII PF09225.10 CAR27249.1 - 0.032 14.0 0.2 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Restriction endonuclease PvuII Pkinase PF00069.25 CAR27250.1 - 1.7e-54 184.9 0.1 7.4e-54 182.9 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27250.1 - 1.7e-27 96.4 0.3 3.8e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 CAR27250.1 - 0.00024 21.7 1.6 0.00024 21.7 1.6 2.5 3 0 0 3 3 3 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CAR27250.1 - 0.0009 18.3 0.3 0.0033 16.4 0.3 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CAR27250.1 - 0.0033 16.8 0.0 0.008 15.6 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CAR27250.1 - 0.0042 16.5 0.0 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CAR27250.1 - 0.14 12.1 0.0 0.71 9.8 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family CwfJ_C_1 PF04677.15 CAR27251.1 - 2.3e-34 117.9 0.3 9.8e-34 115.8 0.1 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CAR27251.1 - 3.8e-15 56.6 0.1 1.1e-14 55.1 0.1 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 UMPH-1 PF05822.12 CAR27251.1 - 0.12 11.9 0.3 0.29 10.6 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) RRM_1 PF00076.22 CAR27252.1 - 2.7e-68 225.7 12.9 1e-16 60.5 0.1 6.4 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR27252.1 - 1.3e-06 28.1 0.0 0.0045 16.6 0.0 4.0 4 1 1 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR27252.1 - 5.2e-06 26.4 0.1 3.3 7.8 0.0 4.8 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CAR27252.1 - 9.8e-06 25.3 0.0 0.072 13.0 0.0 3.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif ClpS PF02617.17 CAR27252.1 - 0.03 14.1 0.0 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS F_actin_bind PF08919.10 CAR27252.1 - 0.041 14.0 0.3 0.11 12.5 0.3 1.7 1 0 0 1 1 1 0 F-actin binding tRNA-synt_1 PF00133.22 CAR27253.1 - 8.4e-236 783.9 1.0 9.9e-235 780.4 1.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CAR27253.1 - 5.2e-32 110.9 0.7 1.9e-31 109.1 0.7 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CAR27253.1 - 1.2e-13 50.6 1.0 1.5e-06 27.3 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CAR27253.1 - 1.2e-08 34.7 0.0 5.5e-08 32.5 0.0 3.4 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 CAR27253.1 - 1.3e-06 28.6 3.1 1.3e-06 28.6 3.1 3.2 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 CAR27253.1 - 0.0023 17.3 0.1 0.39 10.0 0.0 3.2 3 1 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 CAR27253.1 - 1.1 8.5 0.0 1.1 8.5 0.0 3.4 4 0 0 4 4 4 0 tRNA synthetases class I (W and Y) DASH_Spc19 PF08287.11 CAR27253.1 - 8.9 6.2 11.9 8.4 6.3 0.7 2.5 2 0 0 2 2 2 0 Spc19 RNase_PH PF01138.21 CAR27254.1 - 1.2e-18 67.9 0.0 2e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CAR27254.1 - 1.4e-08 34.6 0.2 3.2e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Mito_carr PF00153.27 CAR27255.1 - 4.9e-56 186.7 4.1 2.5e-19 69.0 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CAR27255.1 - 0.007 15.6 0.1 1.9 7.6 0.0 2.4 2 1 0 2 2 2 2 Gammaproteobacterial serine protease ThrE_2 PF12821.7 CAR27255.1 - 0.12 12.6 0.2 0.12 12.6 0.2 2.6 2 1 1 3 3 3 0 Threonine/Serine exporter, ThrE CDP-OH_P_transf PF01066.21 CAR27256.1 - 1.3e-13 51.5 0.3 1.3e-13 51.5 0.3 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ADH_N PF08240.12 CAR27257.1 - 2.4e-30 104.6 0.8 1e-29 102.6 0.2 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR27257.1 - 1.8e-21 76.4 0.7 2.8e-21 75.8 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR27257.1 - 0.0025 18.8 0.0 0.0042 18.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YbjQ_1 PF01906.17 CAR27257.1 - 0.1 13.2 0.6 0.27 11.9 0.1 2.0 2 0 0 2 2 2 0 Putative heavy-metal-binding TRAM_LAG1_CLN8 PF03798.16 CAR27258.1 - 4.5e-31 108.1 19.2 7.1e-31 107.5 19.2 1.3 1 0 0 1 1 1 1 TLC domain Pmp3 PF01679.17 CAR27258.1 - 0.14 12.3 9.5 1.3 9.3 1.2 3.5 3 0 0 3 3 3 0 Proteolipid membrane potential modulator PH PF00169.29 CAR27259.1 - 0.00062 20.2 0.0 0.0019 18.7 0.0 1.9 1 0 0 1 1 1 1 PH domain Flavin_Reduct PF01613.18 CAR27260.1 - 1.3e-30 106.5 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain RRG8 PF17068.5 CAR27261.1 - 2.5e-120 401.1 4.4 2.8e-120 400.9 4.4 1.0 1 0 0 1 1 1 1 Required for respiratory growth protein 8 mitochondrial DUF2283 PF10049.9 CAR27261.1 - 0.017 15.3 0.1 2.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2283) Peptidase_C50 PF03568.17 CAR27262.1 - 3.2e-125 418.3 0.5 7.7e-125 417.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase family C50 DnaB_2 PF07261.11 CAR27262.1 - 0.83 9.4 4.1 5.2 6.9 0.1 3.8 4 0 0 4 4 4 0 Replication initiation and membrane attachment Telomere_reg-2 PF10193.9 CAR27263.1 - 1.1e-22 80.5 0.4 3.7e-22 78.8 0.1 2.1 2 1 1 3 3 3 1 Telomere length regulation protein SAM_1 PF00536.30 CAR27263.1 - 0.79 10.2 2.6 3.7 8.1 0.0 2.7 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Fmp27_WPPW PF10359.9 CAR27264.1 - 7.8e-130 433.9 3.9 7.8e-130 433.9 3.9 1.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 CAR27264.1 - 1.5e-101 340.7 0.0 1.5e-101 340.7 0.0 2.0 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 CAR27264.1 - 4.7e-45 153.5 0.2 1.3e-44 152.0 0.0 1.9 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CAR27264.1 - 2.2e-39 134.9 1.9 2.2e-39 134.9 1.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CAR27264.1 - 3.8e-20 72.5 0.1 5e-19 68.9 0.0 3.1 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain RabGAP-TBC PF00566.18 CAR27265.1 - 1.3e-54 185.1 0.4 3.2e-54 183.8 0.4 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 CAR27265.1 - 2.8e-15 56.2 0.4 8e-15 54.7 0.4 1.8 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 CAR27265.1 - 3.3e-08 32.8 1.4 0.0039 17.0 0.1 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CAR27265.1 - 1.9e-05 25.0 0.5 0.15 12.5 0.2 3.6 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CAR27265.1 - 0.00025 20.4 0.6 0.36 10.5 0.1 3.2 3 0 0 3 3 3 2 EF hand CHDCT2 PF08074.11 CAR27265.1 - 0.02 15.1 1.3 1.1 9.5 0.1 3.3 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain DUF4220 PF13968.6 CAR27265.1 - 0.073 12.5 0.2 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Rhomboid PF01694.22 CAR27266.1 - 7.8e-32 110.3 18.1 7.8e-32 110.3 18.1 1.9 2 1 0 2 2 2 1 Rhomboid family Pescadillo_N PF06732.11 CAR27268.1 - 8.2e-123 409.3 2.9 8.2e-123 409.3 2.9 1.9 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 CAR27268.1 - 3.5e-10 40.2 0.0 9.4e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CAR27268.1 - 0.0034 17.7 0.2 0.027 14.9 0.2 2.5 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CAR27268.1 - 0.055 13.8 0.0 0.26 11.6 0.0 2.3 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Med18 PF09637.10 CAR27269.1 - 1.7e-51 175.5 0.0 1.9e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Med18 protein VMA21 PF09446.10 CAR27270.1 - 1.1e-09 38.3 17.1 1e-08 35.2 17.1 1.9 1 1 0 1 1 1 1 VMA21-like domain ATP-synt_S1 PF05827.12 CAR27271.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Vacuolar ATP synthase subunit S1 (ATP6S1) FlaC_arch PF05377.11 CAR27272.1 - 0.85 10.1 7.4 1.5 9.2 1.7 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IF-2B PF01008.17 CAR27273.1 - 4.1e-82 275.6 0.0 4.9e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family SKN1 PF03935.15 CAR27274.1 - 6.6e-245 813.2 2.8 8.5e-245 812.8 2.8 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SKN1 PF03935.15 CAR27275.1 - 6e-245 813.3 4.2 7e-245 813.1 4.2 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SIS PF01380.22 CAR27276.1 - 3.4e-12 46.4 0.0 4.8e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 CAR27276.1 - 1.4e-08 34.8 0.0 5.3e-05 23.3 0.0 2.3 1 1 1 2 2 2 2 SIS domain Acid_PPase PF12689.7 CAR27277.1 - 4.1e-44 150.4 0.0 4.9e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase AcetylCoA_hydro PF02550.15 CAR27278.1 - 5.2e-59 199.6 0.0 8.3e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 CAR27278.1 - 1.4e-42 145.2 0.0 2.6e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 CAR27278.1 - 0.031 13.7 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Coenzyme A transferase Pkinase PF00069.25 CAR27279.1 - 1.5e-67 227.8 0.0 1.7e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27279.1 - 1.5e-31 109.6 0.0 2e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR27279.1 - 0.00089 18.3 0.4 0.0022 17.0 0.4 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CAR27279.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CAR27279.1 - 0.076 12.9 0.1 0.23 11.3 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CAR27279.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sortilin-Vps10 PF15902.5 CAR27280.1 - 1.8e-205 682.9 0.7 8.6e-139 463.2 0.0 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CAR27280.1 - 4.2e-71 238.8 7.9 7.7e-39 133.8 0.2 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CAR27280.1 - 3.2e-13 47.5 52.8 0.091 12.8 0.1 12.4 12 0 0 12 12 12 7 BNR/Asp-box repeat BNR_2 PF13088.6 CAR27280.1 - 3.3e-07 29.9 1.1 0.0014 18.0 0.0 5.1 3 3 1 4 4 4 2 BNR repeat-like domain CHB_HEX_C PF03174.13 CAR27280.1 - 0.0015 18.5 0.2 8.2 6.5 0.0 4.5 5 0 0 5 5 5 2 Chitobiase/beta-hexosaminidase C-terminal domain Exo_endo_phos PF03372.23 CAR27282.1 - 1.5e-15 57.4 0.0 2.1e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 CAR27282.1 - 2.7e-09 37.0 1.0 5.6e-09 35.9 1.0 1.6 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 CAR27282.1 - 1.3e-05 25.0 0.0 0.025 14.4 0.0 2.6 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Rft-1 PF04506.13 CAR27283.1 - 9.9e-206 684.4 31.5 1.2e-205 684.2 31.5 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 CAR27283.1 - 1e-05 25.1 8.3 1e-05 25.1 8.3 3.2 2 2 1 3 3 3 1 Polysaccharide biosynthesis protein NUDIX PF00293.28 CAR27285.1 - 3.5e-14 53.0 0.0 6.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 CAR27285.1 - 1.2e-05 24.8 0.1 3e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 CAR27285.1 - 0.053 14.2 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain GDPD PF03009.17 CAR27286.1 - 5.1e-29 101.8 0.4 5.8e-28 98.3 0.4 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family SCA7 PF08313.12 CAR27287.1 - 5.4e-30 103.1 0.8 1.6e-29 101.6 0.8 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain zf_C2H2_13 PF18508.1 CAR27287.1 - 8.1e-25 86.1 0.8 1.4e-24 85.4 0.8 1.4 1 0 0 1 1 1 1 Zinc finger domain Glycos_transf_1 PF00534.20 CAR27288.1 - 1.9e-33 115.4 0.0 5.1e-33 114.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CAR27288.1 - 3.6e-19 69.4 0.0 5.8e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CAR27288.1 - 2e-11 44.5 0.0 7.3e-11 42.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CAR27288.1 - 0.0066 16.9 0.0 0.018 15.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 CAR27288.1 - 0.0071 16.4 2.1 3.5 7.6 0.0 3.1 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus MgtE PF01769.16 CAR27288.1 - 0.088 13.2 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Divalent cation transporter DUF1980 PF09323.10 CAR27288.1 - 0.21 11.5 2.8 0.51 10.2 2.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF1992 PF09350.10 CAR27289.1 - 1e-15 57.6 0.0 4.1e-15 55.7 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Wyosine_form PF08608.12 CAR27290.1 - 2.9e-21 75.6 0.0 7.2e-21 74.3 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CAR27290.1 - 1.8e-19 70.7 0.0 3.8e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 CAR27290.1 - 3.5e-13 50.0 0.0 7.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin SET PF00856.28 CAR27291.1 - 6.1e-07 30.0 0.0 1.6e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 SET domain HMA PF00403.26 CAR27293.1 - 0.0097 16.3 2.8 0.035 14.6 1.4 2.4 1 1 1 2 2 2 1 Heavy-metal-associated domain DnaJ_CXXCXGXG PF00684.19 CAR27293.1 - 2.5 8.5 15.0 3.1 8.2 12.1 2.2 2 0 0 2 2 2 0 DnaJ central domain zf-H2C2_2 PF13465.6 CAR27294.1 - 8.7e-08 32.3 5.4 6.7e-06 26.3 2.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CAR27294.1 - 5.1e-05 23.5 15.2 0.0011 19.3 2.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR27294.1 - 0.0064 17.2 12.0 0.24 12.4 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CAR27294.1 - 0.016 15.9 0.4 0.12 13.1 0.0 2.0 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Coprogen_oxidas PF01218.18 CAR27295.1 - 2.5e-136 453.2 0.1 2.8e-136 453.1 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TFIIS_C PF01096.18 CAR27296.1 - 4e-21 74.6 6.5 8.8e-21 73.5 1.9 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CAR27296.1 - 1.1e-13 50.8 2.3 7.2e-13 48.2 0.5 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.13 CAR27296.1 - 0.0072 16.4 1.1 2.3 8.3 0.1 2.5 2 0 0 2 2 2 2 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.7 CAR27296.1 - 0.023 14.7 3.9 2.5 8.1 0.5 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 CAR27296.1 - 0.095 12.7 6.7 0.81 9.7 0.2 3.2 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Baculo_LEF5_C PF11792.8 CAR27296.1 - 0.12 12.0 2.5 0.5 10.1 0.1 2.6 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-piccolo PF05715.13 CAR27296.1 - 0.2 11.8 0.6 0.2 11.8 0.6 2.8 3 0 0 3 3 3 0 Piccolo Zn-finger IBR PF01485.21 CAR27296.1 - 0.29 11.4 9.1 1.3 9.3 0.2 2.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Trs65 PF12735.7 CAR27297.1 - 3.8e-36 125.1 1.0 1.9e-34 119.5 1.0 2.8 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 Clathrin_lg_ch PF01086.17 CAR27298.1 - 1.2e-37 130.2 12.9 1.3e-37 130.1 12.9 1.0 1 0 0 1 1 1 1 Clathrin light chain Ppx-GppA PF02541.16 CAR27298.1 - 0.059 12.8 0.2 0.075 12.5 0.2 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family P35 PF02331.15 CAR27298.1 - 0.073 12.4 1.2 0.087 12.2 1.2 1.1 1 0 0 1 1 1 0 Apoptosis preventing protein DUF4337 PF14235.6 CAR27298.1 - 0.39 10.8 5.9 0.57 10.3 5.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4407 PF14362.6 CAR27298.1 - 1.3 8.3 8.3 1.5 8.1 8.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4065 PF13274.6 CAR27298.1 - 2.9 8.8 7.8 1.9 9.4 4.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) SH3_1 PF00018.28 CAR27300.1 - 7.8e-08 31.8 1.6 3.5e-07 29.7 0.1 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CAR27300.1 - 6.7e-06 25.9 1.0 2.6e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CAR27300.1 - 0.00059 19.5 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PseudoU_synth_2 PF00849.22 CAR27301.1 - 4.9e-26 91.7 0.0 9.5e-26 90.8 0.0 1.5 1 1 0 1 1 1 1 RNA pseudouridylate synthase GNAT_acetyltran PF12746.7 CAR27302.1 - 0.065 12.8 0.2 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 GNAT acetyltransferase DUF4355 PF14265.6 CAR27303.1 - 2.8 8.2 24.8 3.5 7.9 24.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) MAJIN PF15077.6 CAR27303.1 - 9.6 5.9 13.8 10 5.8 13.8 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein AATF-Che1 PF13339.6 CAR27304.1 - 8.1e-25 88.1 3.8 8.1e-25 88.1 3.8 2.9 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 CAR27304.1 - 9.5e-22 77.3 3.1 4.1e-21 75.3 0.1 3.0 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal Pih1_fungal_CS PF18482.1 CAR27305.1 - 8.9e-30 103.1 0.5 1.8e-29 102.1 0.5 1.6 1 0 0 1 1 1 1 Fungal Pih1 CS domain PIH1 PF08190.12 CAR27305.1 - 3.4e-20 72.1 0.4 1.5e-19 70.0 0.4 2.0 1 1 0 1 1 1 1 PIH1 N-terminal domain AA_kinase PF00696.28 CAR27306.1 - 7.3e-34 117.4 0.2 1e-33 116.9 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 CAR27306.1 - 7.6e-20 70.7 0.0 1.5e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 PUA domain CPSF_A PF03178.15 CAR27307.1 - 6.4e-90 301.7 0.1 2e-89 300.1 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region HPS3_N PF14761.6 CAR27307.1 - 0.0011 18.5 1.0 0.6 9.6 0.0 3.4 3 0 0 3 3 3 2 Hermansky-Pudlak syndrome 3 PIG-F PF06699.11 CAR27308.1 - 6.4e-26 91.6 23.9 1.1e-24 87.5 23.9 2.0 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF2070 PF09843.9 CAR27308.1 - 3.2 5.9 8.1 3.5 5.8 8.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AIM24 PF01987.17 CAR27309.1 - 6.3e-13 49.0 0.0 1.6e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 Zn_clus PF00172.18 CAR27310.1 - 7.2e-09 35.6 8.1 1.2e-08 34.9 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 CAR27310.1 - 0.2 10.7 5.6 0.49 9.4 0.9 2.3 2 0 0 2 2 2 0 Clusterin Pro_isomerase PF00160.21 CAR27311.1 - 1.2e-46 158.9 0.2 1.4e-46 158.6 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med6 PF04934.14 CAR27312.1 - 2e-54 183.0 0.0 2.5e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.10 CAR27313.1 - 7.1e-26 90.1 0.5 2.9e-25 88.1 0.2 2.0 2 0 0 2 2 2 1 IGR protein motif PRE_C2HC PF07530.11 CAR27313.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.3 1 0 0 1 1 1 0 Associated with zinc fingers HIT PF01230.23 CAR27314.1 - 2.7e-24 85.8 0.2 4.9e-24 84.9 0.1 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 CAR27314.1 - 3.9e-05 24.1 0.3 6.7e-05 23.3 0.1 1.4 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CAR27314.1 - 0.023 14.6 0.0 0.046 13.6 0.0 1.5 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 LRR_5 PF13306.6 CAR27315.1 - 0.0072 16.3 0.0 0.72 9.8 0.0 2.8 2 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) F-box-like PF12937.7 CAR27315.1 - 0.032 14.1 1.2 0.079 12.9 1.2 1.7 1 0 0 1 1 1 0 F-box-like MIR PF02815.19 CAR27316.1 - 7.1e-15 55.3 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 MIR domain PMT PF02366.18 CAR27316.1 - 8.5e-12 45.2 19.7 8.5e-12 45.2 19.7 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2975 PF11188.8 CAR27316.1 - 4.7 7.1 8.5 1.3 8.9 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2975) Med21 PF11221.8 CAR27317.1 - 6.3e-45 153.0 4.2 8.6e-45 152.5 4.2 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 CAR27317.1 - 0.00032 20.7 0.6 0.0008 19.4 0.3 1.8 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF2200 PF09966.9 CAR27317.1 - 0.0087 16.2 0.6 0.42 10.8 0.0 2.2 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2200) DUF615 PF04751.14 CAR27317.1 - 0.024 14.6 0.6 0.83 9.6 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF615) RNase_P_p30 PF01876.16 CAR27320.1 - 6.3e-70 235.0 0.1 9.9e-70 234.3 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit p30 ApbA PF02558.16 CAR27322.1 - 3.1e-33 114.6 0.0 4.2e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CAR27322.1 - 6.2e-30 104.0 0.1 9.3e-30 103.4 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal HSP70 PF00012.20 CAR27323.1 - 6.4e-80 269.0 0.9 1.8e-76 257.6 0.2 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CAR27323.1 - 5.9e-12 45.0 0.0 9e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein BSD PF03909.17 CAR27324.1 - 1e-22 79.9 1.9 3.8e-12 46.0 0.4 2.9 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 CAR27324.1 - 1.9e-16 60.1 0.2 1.9e-16 60.1 0.2 1.8 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Ndc1_Nup PF09531.10 CAR27324.1 - 0.024 13.4 0.3 0.098 11.3 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Remorin_C PF03763.13 CAR27324.1 - 0.044 13.7 1.0 0.2 11.5 1.0 2.1 1 0 0 1 1 1 0 Remorin, C-terminal region GAT PF03127.14 CAR27324.1 - 0.059 13.7 1.7 0.34 11.2 0.0 3.1 3 0 0 3 3 3 0 GAT domain DEAD PF00270.29 CAR27325.1 - 2.4e-50 170.7 0.0 4.3e-50 169.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR27325.1 - 1.4e-31 109.1 0.1 5.9e-31 107.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR27325.1 - 3.2e-07 30.5 0.2 3e-06 27.3 0.0 2.4 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CAR27325.1 - 0.0045 17.3 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain MecA PF05389.12 CAR27325.1 - 0.19 11.3 4.7 1.1 8.9 5.7 1.7 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Brix PF04427.18 CAR27326.1 - 3.9e-49 167.4 4.3 6.9e-49 166.6 4.3 1.4 1 0 0 1 1 1 1 Brix domain DUF755 PF05501.11 CAR27326.1 - 5 7.4 19.6 0.39 11.0 12.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) PPL5 PF18168.1 CAR27326.1 - 6.3 6.0 12.2 1.3 8.2 8.7 1.6 1 1 0 1 1 1 0 Prim-pol family 5 FYVE PF01363.21 CAR27327.1 - 4e-18 65.3 12.6 4e-18 65.3 12.6 3.4 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 CAR27327.1 - 2.2e-06 27.9 5.9 2.2e-06 27.9 5.9 3.8 4 0 0 4 4 4 1 Ring finger domain zf-RING_11 PF17123.5 CAR27327.1 - 8.7e-06 25.4 4.5 8.7e-06 25.4 4.5 2.9 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CAR27327.1 - 0.0011 18.9 6.1 0.0011 18.9 6.1 3.6 3 1 0 3 3 3 1 RING-type zinc-finger FANCL_C PF11793.8 CAR27327.1 - 0.013 15.7 4.6 0.013 15.7 4.6 2.9 3 1 0 3 3 3 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 CAR27327.1 - 0.015 15.1 3.2 0.015 15.1 3.2 4.3 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) RNF220 PF15926.5 CAR27327.1 - 0.022 14.4 0.4 0.022 14.4 0.4 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 YdjO PF14169.6 CAR27327.1 - 0.51 10.1 8.6 0.92 9.3 0.1 3.4 3 0 0 3 3 3 0 Cold-inducible protein YdjO BHD_1 PF10403.9 CAR27328.1 - 1.8e-12 46.9 0.2 7.9e-12 44.8 0.0 2.4 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_3 PF10405.9 CAR27328.1 - 4e-12 46.4 0.0 3.1e-11 43.5 0.0 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 CAR27328.1 - 1.3e-09 37.9 0.1 3.3e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 CAR27328.1 - 0.001 19.9 2.2 0.0013 19.6 0.2 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 FAD_binding_7 PF03441.14 CAR27328.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase MaoC_dehydratas PF01575.19 CAR27329.1 - 0.095 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 MaoC like domain Ins_P5_2-kin PF06090.12 CAR27330.1 - 1.7e-16 60.6 0.0 2.9e-14 53.3 0.0 2.1 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DS PF01916.17 CAR27331.1 - 2.9e-133 443.5 0.0 3.4e-133 443.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Methyltransf_23 PF13489.6 CAR27332.1 - 3e-21 76.0 0.0 4.4e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR27332.1 - 3e-12 47.1 0.4 1.6e-11 44.8 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR27332.1 - 3.3e-11 43.8 0.0 4.5e-08 33.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR27332.1 - 1.9e-08 34.9 0.0 7.6e-06 26.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR27332.1 - 1.4e-07 31.1 0.0 0.0033 16.8 0.0 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CAR27332.1 - 3.2e-06 27.0 0.0 1.4e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain ECR1_N PF14382.6 CAR27333.1 - 5.2e-17 61.3 0.3 1e-16 60.4 0.3 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CAR27333.1 - 9.9e-10 38.6 0.2 2.2e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 CAR27333.1 - 0.13 12.9 0.0 29 5.3 0.0 2.8 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Met_10 PF02475.16 CAR27334.1 - 3.2e-76 255.5 0.0 9.4e-76 254.0 0.0 1.8 2 1 0 2 2 2 1 Met-10+ like-protein TRM PF02005.16 CAR27334.1 - 0.00025 20.3 0.0 0.00048 19.4 0.0 1.4 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MethyltransfD12 PF02086.15 CAR27334.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase PrmA PF06325.13 CAR27334.1 - 0.041 13.3 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cyclin_N PF00134.23 CAR27335.1 - 1.6e-06 27.9 0.3 2.1e-06 27.5 0.3 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF3563 PF12086.8 CAR27335.1 - 0.19 11.5 4.0 0.64 9.8 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3563) GAF_2 PF13185.6 CAR27336.1 - 3.2e-10 40.4 0.0 4.9e-10 39.8 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.26 CAR27336.1 - 1.7e-07 31.9 0.0 2.2e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 GAF domain PRP4 PF08799.11 CAR27336.1 - 0.033 13.7 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like GAF_3 PF13492.6 CAR27336.1 - 0.039 14.3 0.0 0.78 10.1 0.0 2.1 1 1 1 2 2 2 0 GAF domain SpoVT_C PF15714.5 CAR27336.1 - 0.039 14.0 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein T C-terminal, transcription factor DUF285 PF03382.14 CAR27338.1 - 0.0057 16.4 2.4 0.014 15.2 2.4 1.6 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 SMG1 PF15785.5 CAR27338.1 - 0.19 10.1 4.8 0.67 8.3 1.7 2.0 2 0 0 2 2 2 0 Serine/threonine-protein kinase smg-1 WD40 PF00400.32 CAR27339.1 - 9.4e-13 48.4 12.8 0.00013 22.7 0.4 5.3 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27339.1 - 1.3e-10 41.4 6.9 0.0023 18.2 0.5 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR27339.1 - 4.1e-08 32.6 0.3 1.2e-05 24.4 0.1 3.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CAR27339.1 - 0.00068 19.6 1.3 0.41 10.5 0.1 3.3 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A CBS PF00571.28 CAR27340.1 - 6.9e-26 90.5 6.1 1.3e-13 51.2 0.1 4.3 4 0 0 4 4 4 4 CBS domain Acetyltransf_4 PF13420.7 CAR27340.1 - 0.16 12.1 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_9 PF08221.11 CAR27340.1 - 0.33 11.1 2.8 1.7 8.8 0.1 2.9 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain OPT PF03169.15 CAR27341.1 - 5.2e-155 517.5 18.9 5.9e-155 517.4 18.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1189 PF06691.11 CAR27341.1 - 0.029 14.0 1.4 0.076 12.6 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) DUF4383 PF14325.6 CAR27341.1 - 0.031 14.6 0.5 0.031 14.6 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4383) BCNT PF07572.12 CAR27342.1 - 8.7e-24 83.4 0.2 8.7e-24 83.4 0.2 2.8 3 0 0 3 3 3 1 Bucentaur or craniofacial development KH_1 PF00013.29 CAR27343.1 - 1.3e-34 117.9 3.8 2.6e-12 46.4 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CAR27343.1 - 9.9e-12 44.5 0.3 0.0059 16.4 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CAR27343.1 - 2.1e-08 33.9 1.3 0.036 13.9 0.1 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 CAR27343.1 - 0.0031 17.6 1.5 7 6.8 0.1 3.5 3 0 0 3 3 3 1 NusA-like KH domain SLD3 PF08639.10 CAR27344.1 - 2.7e-42 145.3 19.8 4.2e-41 141.3 19.8 2.3 1 1 0 1 1 1 1 DNA replication regulator SLD3 Sld3_N PF18523.1 CAR27344.1 - 2.4e-27 95.3 0.6 5.1e-27 94.3 0.0 1.9 2 0 0 2 2 2 1 Sld3 N-terminal domain TAF PF02969.17 CAR27345.1 - 2.8e-30 104.3 0.4 6.4e-30 103.1 0.4 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TAF6_C PF07571.13 CAR27345.1 - 1.3e-29 102.3 0.0 2.6e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain Histone PF00125.24 CAR27345.1 - 0.00078 19.8 0.4 0.0022 18.4 0.2 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 CAR27345.1 - 0.0018 18.3 1.0 0.0049 16.9 0.2 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit DUF348 PF03990.14 CAR27345.1 - 0.0095 15.7 0.0 0.038 13.7 0.0 2.1 1 0 0 1 1 1 1 G5-linked-Ubiquitin-like domain CBFD_NFYB_HMF PF00808.23 CAR27345.1 - 0.012 15.9 0.4 0.035 14.4 0.1 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF4 PF05236.14 CAR27345.1 - 0.03 14.1 0.1 0.054 13.2 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DASH_Dad3 PF08656.10 CAR27346.1 - 4.9e-26 90.6 0.3 5.6e-26 90.4 0.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 WD40 PF00400.32 CAR27347.1 - 1.7e-11 44.4 7.7 0.00075 20.3 0.4 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27347.1 - 1.1e-10 41.6 0.1 0.0021 18.3 0.0 4.5 2 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Me-amine-dh_H PF06433.11 CAR27348.1 - 0.0042 16.0 0.0 2.6 6.8 0.0 2.7 2 1 1 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) CUE PF02845.16 CAR27349.1 - 8.4e-08 31.8 0.0 2.3e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 CAR27349.1 - 0.019 14.7 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Ku_N PF03731.15 CAR27350.1 - 3.6e-35 121.7 0.6 3.6e-35 121.7 0.6 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 CAR27350.1 - 6.5e-31 107.6 0.0 1.2e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 CAR27350.1 - 1.8e-07 31.8 0.4 9.3e-07 29.5 0.4 2.4 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm RecT PF03837.14 CAR27350.1 - 0.0062 16.0 0.1 0.016 14.7 0.1 1.6 1 0 0 1 1 1 1 RecT family VWA PF00092.28 CAR27350.1 - 0.016 15.5 0.0 0.045 14.0 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain Exo_endo_phos PF03372.23 CAR27351.1 - 8.3e-30 104.0 0.1 1.1e-29 103.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L30 PF00327.20 CAR27352.1 - 3.8e-15 55.5 0.2 6e-15 54.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Baculo_helicase PF04735.12 CAR27353.1 - 0.11 10.0 0.0 0.14 9.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus DNA helicase RNB PF00773.19 CAR27354.1 - 2.6e-63 214.4 0.0 7.7e-63 212.8 0.0 1.9 2 0 0 2 2 2 1 RNB domain DUF3952 PF13130.6 CAR27354.1 - 0.035 14.3 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3952) Vps53_N PF04100.12 CAR27354.1 - 0.1 11.5 0.1 0.26 10.2 0.1 1.6 1 0 0 1 1 1 0 Vps53-like, N-terminal Pyr_redox_2 PF07992.14 CAR27355.1 - 7.7e-49 166.5 0.0 9.3e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR27355.1 - 2.2e-10 41.0 0.0 8.8e-08 32.6 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR27355.1 - 7.1e-07 28.8 0.3 0.31 10.2 0.1 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAR27355.1 - 0.14 10.8 0.3 13 4.3 0.0 3.0 4 0 0 4 4 4 0 HI0933-like protein Brix PF04427.18 CAR27356.1 - 1e-29 104.0 0.2 1.4e-29 103.6 0.2 1.2 1 0 0 1 1 1 1 Brix domain DUF1752 PF08550.10 CAR27357.1 - 2e-09 37.1 0.0 4.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MMPL PF03176.15 CAR27358.1 - 0.0045 16.0 1.2 0.012 14.6 1.2 1.7 1 0 0 1 1 1 1 MMPL family Apolipoprotein PF01442.18 CAR27358.1 - 0.13 12.1 22.1 0.53 10.1 9.0 3.2 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain MHB PF16525.5 CAR27358.1 - 0.14 12.4 0.2 0.14 12.4 0.2 2.9 4 1 0 4 4 4 0 Haemophore, haem-binding T7SS_ESX_EspC PF10824.8 CAR27358.1 - 0.27 11.7 6.7 7.2 7.1 0.0 3.5 2 1 1 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm ANAPC5 PF12862.7 CAR27358.1 - 1.5 8.9 4.9 9.5 6.4 0.2 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 Borrelia_orfA PF02414.15 CAR27358.1 - 2.8 7.5 8.5 0.094 12.3 1.7 1.9 2 1 0 2 2 2 0 Borrelia ORF-A DUF2508 PF10704.9 CAR27358.1 - 6.1 7.1 9.4 0.36 11.0 0.5 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2508) TMPIT PF07851.13 CAR27358.1 - 8.7 5.5 10.3 16 4.6 0.2 3.2 3 0 0 3 3 3 0 TMPIT-like protein DUF883 PF05957.13 CAR27358.1 - 9.1 7.0 23.4 0.27 11.9 3.2 4.9 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF883) DnaJ_C PF01556.18 CAR27359.1 - 1.7e-28 99.6 0.0 2.4e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAR27359.1 - 7.5e-23 80.4 3.3 1.4e-22 79.6 3.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAR27359.1 - 5.4e-13 49.1 19.1 1.4e-12 47.8 19.1 1.8 1 0 0 1 1 1 1 DnaJ central domain TackOD1 PF18551.1 CAR27359.1 - 0.4 10.3 7.3 2.7 7.6 1.6 2.5 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 CAR27359.1 - 0.56 10.3 11.7 1.9 8.6 11.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon RseC_MucC PF04246.12 CAR27359.1 - 1.3 9.0 4.7 4.8 7.1 0.2 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Peptidase_M1 PF01433.20 CAR27360.1 - 1.9e-48 164.9 0.4 4.1e-48 163.8 0.4 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CAR27360.1 - 1.2e-41 143.3 0.1 2.6e-41 142.2 0.1 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CAR27360.1 - 7.3e-32 111.1 1.1 1.5e-31 110.0 1.1 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Aminopep PF10023.9 CAR27360.1 - 0.001 18.5 0.1 0.0024 17.3 0.1 1.6 2 0 0 2 2 2 1 Putative aminopeptidase RED_C PF07807.11 CAR27361.1 - 0.11 13.0 0.2 0.2 12.1 0.2 1.4 1 0 0 1 1 1 0 RED-like protein C-terminal region Tropomyosin_1 PF12718.7 CAR27362.1 - 2.8e-53 179.9 47.0 3.3e-53 179.7 47.0 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 CAR27362.1 - 2.1e-06 27.3 42.7 0.0037 16.7 14.5 2.1 1 1 1 2 2 2 2 Tropomyosin Spc7 PF08317.11 CAR27362.1 - 0.00011 21.2 41.4 0.003 16.5 14.5 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CAR27362.1 - 0.00028 20.9 13.7 0.00028 20.9 13.7 2.9 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KLRAQ PF10205.9 CAR27362.1 - 0.00029 21.0 31.5 0.043 14.1 14.5 2.1 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein GAS PF13851.6 CAR27362.1 - 0.00043 19.7 41.9 0.13 11.6 41.1 2.8 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding IFT57 PF10498.9 CAR27362.1 - 0.0023 17.0 11.6 0.0023 17.0 11.6 2.4 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 Laminin_II PF06009.12 CAR27362.1 - 0.0042 17.1 25.2 0.037 14.0 10.6 2.1 1 1 1 2 2 2 2 Laminin Domain II WXG100 PF06013.12 CAR27362.1 - 0.0068 16.6 13.7 0.62 10.3 0.1 3.9 2 1 1 3 3 3 1 Proteins of 100 residues with WXG Jnk-SapK_ap_N PF09744.9 CAR27362.1 - 0.0085 16.3 29.5 0.0085 16.3 29.5 2.1 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 DivIC PF04977.15 CAR27362.1 - 0.0091 15.7 7.7 0.0091 15.7 7.7 4.1 1 1 3 4 4 4 1 Septum formation initiator ADIP PF11559.8 CAR27362.1 - 0.012 15.8 39.0 0.13 12.3 13.7 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 CAR27362.1 - 0.013 15.6 46.6 1.5 8.9 15.9 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 CAR27362.1 - 0.015 15.3 52.9 0.043 13.8 18.1 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding MbeD_MobD PF04899.12 CAR27362.1 - 0.021 14.9 1.7 0.021 14.9 1.7 2.9 2 1 1 3 3 3 0 MbeD/MobD like ATG16 PF08614.11 CAR27362.1 - 0.024 14.9 40.3 0.28 11.4 14.2 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.19 CAR27362.1 - 0.027 14.3 43.1 0.22 11.3 41.0 2.0 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF724 PF05266.14 CAR27362.1 - 0.029 14.2 33.0 0.095 12.5 15.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF5595 PF18077.1 CAR27362.1 - 0.032 14.3 8.6 0.032 14.3 8.6 3.5 2 2 1 3 3 2 0 Domain of unknown function (DUF5595) bZIP_1 PF00170.21 CAR27362.1 - 0.035 14.2 41.2 0.98 9.6 4.1 4.9 2 1 2 4 4 4 0 bZIP transcription factor DUF1664 PF07889.12 CAR27362.1 - 0.035 14.1 19.7 0.11 12.5 6.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Taxilin PF09728.9 CAR27362.1 - 0.038 13.2 41.2 0.02 14.1 15.0 2.8 1 1 2 3 3 3 0 Myosin-like coiled-coil protein DUF3450 PF11932.8 CAR27362.1 - 0.064 12.6 34.2 0.43 9.9 10.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 CAR27362.1 - 0.09 13.2 36.1 0.073 13.5 34.5 1.5 1 1 0 1 1 1 0 Fez1 APG6_N PF17675.1 CAR27362.1 - 0.093 13.3 51.9 1.4 9.5 19.7 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Filament PF00038.21 CAR27362.1 - 0.16 11.6 35.8 0.074 12.6 16.6 2.0 1 1 1 2 2 2 0 Intermediate filament protein Atg14 PF10186.9 CAR27362.1 - 0.17 11.0 34.0 0.32 10.0 22.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BLOC1_2 PF10046.9 CAR27362.1 - 0.17 12.2 31.3 0.56 10.5 9.4 3.9 1 1 1 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4201 PF13870.6 CAR27362.1 - 0.21 11.3 37.8 2.7 7.7 37.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Sec34 PF04136.15 CAR27362.1 - 0.21 11.4 27.1 1.7 8.5 15.1 2.1 1 1 1 2 2 2 0 Sec34-like family Uso1_p115_C PF04871.13 CAR27362.1 - 0.28 11.6 45.7 1.8 8.9 17.8 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region KASH_CCD PF14662.6 CAR27362.1 - 0.3 10.9 44.0 0.33 10.7 18.5 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ZapB PF06005.12 CAR27362.1 - 0.35 11.4 51.4 8 7.0 18.5 4.0 1 1 1 3 3 3 0 Cell division protein ZapB DUF4200 PF13863.6 CAR27362.1 - 0.44 11.0 43.3 2 8.8 21.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) EzrA PF06160.12 CAR27362.1 - 0.46 8.6 38.6 0.71 8.0 15.0 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF745 PF05335.13 CAR27362.1 - 0.63 9.7 22.6 0.93 9.2 7.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF3584 PF12128.8 CAR27362.1 - 0.65 7.4 34.4 0.9 7.0 34.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lebercilin PF15619.6 CAR27362.1 - 0.81 9.3 41.5 1.1 8.9 21.9 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Swi5 PF07061.11 CAR27362.1 - 0.81 9.8 38.1 1.2 9.3 7.7 4.0 1 1 3 4 4 4 0 Swi5 Sec2p PF06428.11 CAR27362.1 - 0.82 9.7 40.3 0.35 10.8 19.9 3.5 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p MIS13 PF08202.11 CAR27362.1 - 0.85 8.8 33.0 2.3 7.4 12.3 2.1 1 1 1 2 2 2 0 Mis12-Mtw1 protein family AAA_13 PF13166.6 CAR27362.1 - 0.85 8.2 32.3 0.047 12.3 11.3 2.1 1 1 1 2 2 2 0 AAA domain PI3K_P85_iSH2 PF16454.5 CAR27362.1 - 0.93 9.1 35.9 0.85 9.2 29.9 2.3 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain NPV_P10 PF05531.12 CAR27362.1 - 1.1 9.8 15.2 10 6.6 0.1 3.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc24 PF08286.11 CAR27362.1 - 1.2 9.4 39.3 1.7 8.9 5.7 4.0 1 1 2 3 3 2 0 Spc24 subunit of Ndc80 CENP-K PF11802.8 CAR27362.1 - 1.3 8.5 34.9 0.52 9.8 12.6 2.0 1 1 1 2 2 2 0 Centromere-associated protein K Occludin_ELL PF07303.13 CAR27362.1 - 1.3 9.8 28.5 5.1 7.9 8.4 3.0 1 1 2 3 3 3 0 Occludin homology domain HrpB7 PF09486.10 CAR27362.1 - 1.5 9.2 18.9 5.1 7.5 17.6 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) T2SSM PF04612.12 CAR27362.1 - 1.5 8.9 16.4 0.26 11.3 2.8 3.2 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein M Ax_dynein_light PF10211.9 CAR27362.1 - 1.5 8.7 42.6 2.1 8.2 8.0 3.5 1 1 2 3 3 3 0 Axonemal dynein light chain TMPIT PF07851.13 CAR27362.1 - 2.1 7.5 31.2 1 8.6 14.2 2.0 1 1 1 2 2 2 0 TMPIT-like protein HMMR_C PF15908.5 CAR27362.1 - 2.2 8.6 29.3 13 6.1 5.5 3.5 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Uds1 PF15456.6 CAR27362.1 - 2.2 8.5 32.3 0.17 12.0 19.1 3.0 1 1 2 3 3 3 0 Up-regulated During Septation OmpH PF03938.14 CAR27362.1 - 2.6 8.4 37.3 0.95 9.8 17.5 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Fib_alpha PF08702.10 CAR27362.1 - 3 8.0 27.3 19 5.4 16.1 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 CAR27362.1 - 3.2 8.2 31.7 1.2 9.6 3.3 4.4 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.9 CAR27362.1 - 3.3 8.5 25.0 2.3 9.0 9.5 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) FUSC PF04632.12 CAR27362.1 - 3.5 6.1 5.3 4.1 5.8 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CLZ PF16526.5 CAR27362.1 - 3.7 8.0 33.4 5.4 7.5 10.9 3.8 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UPF0242 PF06785.11 CAR27362.1 - 3.9 7.5 44.6 2.2 8.4 18.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CALCOCO1 PF07888.11 CAR27362.1 - 3.9 6.2 39.1 5.8 5.6 17.4 1.9 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF948 PF06103.11 CAR27362.1 - 4.6 7.6 13.3 4.5 7.6 2.0 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 CAR27362.1 - 4.9 7.4 35.6 0.8 10.0 3.0 4.3 1 1 2 4 4 4 0 Haemolysin XhlA DUF4407 PF14362.6 CAR27362.1 - 5.3 6.3 25.6 12 5.1 25.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DHR10 PF18595.1 CAR27362.1 - 5.9 7.0 43.9 3.8 7.6 16.2 2.7 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain Lectin_N PF03954.14 CAR27362.1 - 6.5 6.5 21.7 4.5 7.0 7.5 3.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain CENP-H PF05837.12 CAR27362.1 - 6.7 7.2 35.9 6.2 7.3 12.3 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) HIP1_clath_bdg PF16515.5 CAR27362.1 - 7 7.3 39.1 1 10.0 20.5 3.2 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FAA_hydro_N_2 PF18288.1 CAR27362.1 - 7.2 7.1 15.9 1.7 9.1 1.3 3.6 1 1 3 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 DUF16 PF01519.16 CAR27362.1 - 7.3 7.1 27.1 5.3 7.6 11.1 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 bZIP_2 PF07716.15 CAR27362.1 - 7.5 6.7 37.6 0.091 12.9 2.1 4.8 2 2 2 4 4 3 0 Basic region leucine zipper Nup54 PF13874.6 CAR27362.1 - 8.1 6.5 25.3 1.3e+04 -3.8 25.3 2.5 1 1 0 1 1 0 0 Nucleoporin complex subunit 54 Rho_Binding PF08912.11 CAR27362.1 - 8.5 7.3 47.8 1.8 9.4 4.6 4.0 1 1 2 3 3 2 0 Rho Binding HemX PF04375.14 CAR27362.1 - 9 5.5 28.8 2.8 7.1 11.4 2.1 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF812 PF05667.11 CAR27362.1 - 9.1 5.0 39.8 1.4e+02 1.1 39.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) FapA PF03961.13 CAR27362.1 - 9.5 4.7 35.5 2.1 6.8 14.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A FliD_C PF07195.12 CAR27362.1 - 9.9 5.5 24.5 6.1 6.2 0.5 3.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus EOS1 PF12326.8 CAR27363.1 - 1.8e-54 184.3 18.6 4.4e-41 140.7 15.6 2.2 1 1 1 2 2 2 2 N-glycosylation protein Ribosomal_S13 PF00416.22 CAR27364.1 - 1.1e-17 64.6 0.1 9.2e-16 58.4 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CAR27364.1 - 0.033 13.0 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.8 CAR27364.1 - 0.081 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif MutL_C PF08676.11 CAR27365.1 - 5.5e-25 87.9 0.0 1.3e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CAR27365.1 - 3.3e-24 84.9 0.3 2.7e-23 81.9 0.1 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CAR27365.1 - 3.9e-13 49.4 0.1 1.2e-12 47.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CAR27365.1 - 2.9e-08 34.2 0.1 8.9e-08 32.6 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HORMA PF02301.18 CAR27366.1 - 2.2e-10 40.5 0.2 3.4e-10 39.9 0.2 1.4 1 1 0 1 1 1 1 HORMA domain Mito_carr PF00153.27 CAR27367.1 - 1.5e-63 210.8 2.4 4.7e-21 74.5 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 CAR27367.1 - 1.1e-14 54.6 5.8 5.3e-09 36.4 2.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAR27367.1 - 1.2e-10 40.5 1.2 0.034 14.1 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CAR27367.1 - 1.1e-08 34.0 1.0 0.079 12.6 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CAR27367.1 - 3.2e-07 30.1 1.5 0.0033 17.2 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 CAR27367.1 - 9.5e-07 28.1 0.0 0.074 12.6 0.0 2.8 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 CAR27367.1 - 0.093 13.1 0.4 6.7 7.1 0.2 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region 4HBT PF03061.22 CAR27368.1 - 0.0034 17.7 0.5 0.57 10.6 0.1 3.0 3 0 0 3 3 3 2 Thioesterase superfamily He_PIG PF05345.12 CAR27369.1 - 7.6e-12 45.2 12.0 0.00023 21.3 0.5 4.2 4 0 0 4 4 4 3 Putative Ig domain SKG6 PF08693.10 CAR27369.1 - 3.3e-11 42.4 0.5 3.3e-11 42.4 0.5 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 CAR27369.1 - 0.0014 18.5 0.1 0.0053 16.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) MGC-24 PF05283.11 CAR27369.1 - 0.0087 16.5 1.1 0.0087 16.5 1.1 3.0 2 1 1 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin VSP PF03302.13 CAR27369.1 - 0.082 11.8 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein RIFIN PF02009.16 CAR27369.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 Rifin ketoacyl-synt PF00109.26 CAR27369.1 - 0.63 9.6 3.5 1.3 8.5 3.5 1.5 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain EF-hand_4 PF12763.7 CAR27370.1 - 7.4e-52 173.7 4.1 1.4e-49 166.4 2.4 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 CAR27370.1 - 3.1e-38 132.0 8.0 1.6e-37 129.6 8.0 1.9 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Csm1_N PF18504.1 CAR27370.1 - 0.0014 19.0 4.4 1.1 9.6 0.7 3.1 2 0 0 2 2 2 2 Csm1 N-terminal domain EF-hand_1 PF00036.32 CAR27370.1 - 0.0044 16.5 1.4 0.028 14.0 1.8 2.1 2 0 0 2 2 2 1 EF hand Cep57_CLD_2 PF14197.6 CAR27370.1 - 0.0065 16.5 0.8 0.0065 16.5 0.8 2.7 2 1 0 2 2 2 1 Centrosome localisation domain of PPC89 IFT20 PF14931.6 CAR27370.1 - 0.027 14.6 3.4 3.7 7.7 1.5 3.0 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 DUF5320 PF17253.2 CAR27370.1 - 0.054 14.6 2.6 5.5 8.1 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Sugarporin_N PF11471.8 CAR27370.1 - 0.058 13.4 0.0 0.058 13.4 0.0 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension CC2-LZ PF16516.5 CAR27370.1 - 0.072 13.5 2.4 1.7 9.1 0.3 2.5 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator GIT_CC PF16559.5 CAR27370.1 - 0.084 12.8 0.2 0.084 12.8 0.2 2.9 4 0 0 4 4 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Prefoldin_2 PF01920.20 CAR27370.1 - 0.094 12.7 7.0 0.28 11.2 0.9 2.8 2 1 0 2 2 2 0 Prefoldin subunit Nsp1_C PF05064.13 CAR27370.1 - 0.12 12.2 2.5 0.36 10.7 0.5 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region Spc24 PF08286.11 CAR27370.1 - 0.14 12.4 8.7 2.9 8.2 2.0 2.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FliJ PF02050.16 CAR27370.1 - 0.16 12.2 11.7 0.51 10.6 2.8 2.8 2 1 1 3 3 3 0 Flagellar FliJ protein CCDC144C PF14915.6 CAR27370.1 - 0.17 11.0 8.0 4 6.5 7.2 2.2 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Macoilin PF09726.9 CAR27370.1 - 0.17 10.4 6.4 0.19 10.2 6.4 1.1 1 0 0 1 1 1 0 Macoilin family FlaC_arch PF05377.11 CAR27370.1 - 0.17 12.3 7.2 3.9 7.9 2.0 2.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 CAR27370.1 - 0.3 11.6 10.0 0.42 11.1 2.5 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 CAR27370.1 - 0.44 9.9 5.9 0.68 9.2 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 CAR27370.1 - 0.44 11.0 3.9 11 6.6 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PI3K_P85_iSH2 PF16454.5 CAR27370.1 - 0.59 9.7 8.2 2 8.0 3.6 2.3 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4164 PF13747.6 CAR27370.1 - 0.61 10.4 5.9 1.6 9.1 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) FapA PF03961.13 CAR27370.1 - 0.73 8.4 3.2 1.9 7.0 3.2 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 CAR27370.1 - 1 10.1 7.0 1.7 9.3 0.5 2.5 1 1 1 2 2 2 0 Initiation control protein YabA CCDC-167 PF15188.6 CAR27370.1 - 1.1 9.7 8.5 45 4.5 8.5 2.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Fib_alpha PF08702.10 CAR27370.1 - 1.2 9.3 9.1 15 5.7 7.8 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 CAR27370.1 - 1.4 9.1 9.6 5.8 7.2 9.6 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF641 PF04859.12 CAR27370.1 - 1.5 9.2 6.8 2.7 8.3 2.0 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Uds1 PF15456.6 CAR27370.1 - 1.5 9.0 8.7 2 8.6 1.3 2.3 2 0 0 2 2 2 0 Up-regulated During Septation DUF2730 PF10805.8 CAR27370.1 - 2.1 8.5 5.2 25 5.0 0.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) ZapB PF06005.12 CAR27370.1 - 2.2 8.8 8.5 1 9.8 1.8 2.7 2 0 0 2 2 2 0 Cell division protein ZapB DUF4140 PF13600.6 CAR27370.1 - 2.2 8.7 6.2 2.6 8.5 0.3 2.6 3 0 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) ABC_tran_CTD PF16326.5 CAR27370.1 - 7 7.0 8.0 2.6 8.3 0.2 2.8 3 0 0 3 3 2 0 ABC transporter C-terminal domain DivIC PF04977.15 CAR27370.1 - 8.3 6.3 10.3 4.5 7.1 0.1 3.0 3 0 0 3 3 3 0 Septum formation initiator YlqD PF11068.8 CAR27370.1 - 9.6 6.6 9.2 2e+02 2.3 9.2 2.3 1 1 0 1 1 1 0 YlqD protein Cpn60_TCP1 PF00118.24 CAR27371.1 - 6.8e-146 486.7 8.9 7.8e-146 486.5 8.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family V-SNARE PF05008.15 CAR27371.1 - 0.045 14.1 3.3 2.5 8.5 0.2 3.4 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus CRM1_repeat PF18777.1 CAR27371.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF1104 PF06518.11 CAR27371.1 - 0.57 10.6 4.0 0.37 11.2 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) MKT1_C PF12246.8 CAR27372.1 - 2.5e-59 200.4 4.0 1.3e-58 198.1 4.4 1.9 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CAR27372.1 - 1.2e-27 96.1 0.2 1.6e-26 92.5 0.0 2.9 3 1 0 3 3 3 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 CAR27372.1 - 3.7e-20 72.3 0.0 1.5e-19 70.3 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain OST3_OST6 PF04756.13 CAR27373.1 - 6.3e-77 258.8 0.1 7.2e-77 258.6 0.1 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Lig_chan PF00060.26 CAR27373.1 - 0.0088 15.9 2.9 0.015 15.1 1.3 2.0 2 0 0 2 2 2 1 Ligand-gated ion channel DUF4131 PF13567.6 CAR27373.1 - 1.6 8.3 3.7 12 5.6 3.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Snapin_Pallidin PF14712.6 CAR27374.1 - 2.2e-07 31.2 3.4 2.8e-07 30.9 3.4 1.1 1 0 0 1 1 1 1 Snapin/Pallidin YscO PF07321.12 CAR27374.1 - 0.004 17.1 1.8 0.5 10.3 0.0 2.0 2 0 0 2 2 2 2 Type III secretion protein YscO HALZ PF02183.18 CAR27374.1 - 0.085 13.1 1.3 0.085 13.1 1.3 2.8 1 1 2 3 3 3 0 Homeobox associated leucine zipper C2 PF00168.30 CAR27375.1 - 1.2e-56 189.4 3.8 1.7e-20 73.2 0.0 4.9 5 0 0 5 5 5 4 C2 domain SMP_LBD PF17047.5 CAR27375.1 - 0.00068 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain COX2-transmemb PF09125.10 CAR27375.1 - 2.7 7.9 4.1 5.7 6.8 4.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane DNA_topoisoIV PF00521.20 CAR27376.1 - 1.1e-118 396.9 0.0 1.1e-118 396.9 0.0 2.0 3 0 0 3 3 3 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CAR27376.1 - 2.7e-50 169.9 0.4 7e-50 168.6 0.4 1.8 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CAR27376.1 - 5e-25 88.0 0.3 1e-24 87.0 0.3 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CAR27376.1 - 1.4e-13 51.3 0.1 7.1e-13 49.1 0.0 2.2 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CAR27376.1 - 2.8e-07 30.7 0.0 9.2e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Toprim domain DTHCT PF08070.11 CAR27376.1 - 0.011 16.4 15.4 0.011 16.4 15.4 4.2 1 1 3 4 4 4 0 DTHCT (NUC029) region Ras PF00071.22 CAR27377.1 - 6.1e-49 165.7 0.0 7e-49 165.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR27377.1 - 2.5e-21 76.1 0.0 3.6e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR27377.1 - 4.7e-08 32.7 0.0 6.3e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 CAR27377.1 - 0.0045 16.8 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 CAR27377.1 - 0.036 13.9 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SRPRB PF09439.10 CAR27377.1 - 0.037 13.5 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NST1 PF13945.6 CAR27378.1 - 5.9e-09 36.3 25.8 5.9e-09 36.3 25.8 8.7 5 3 2 7 7 7 2 Salt tolerance down-regulator TFIIA PF03153.13 CAR27378.1 - 0.00099 19.2 27.3 0.00099 19.2 27.3 7.2 1 1 5 7 7 7 1 Transcription factor IIA, alpha/beta subunit EMC3_TMCO1 PF01956.16 CAR27379.1 - 0.1 12.3 0.1 0.1 12.3 0.1 2.6 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Pkr1 PF08636.10 CAR27379.1 - 0.23 11.6 0.0 0.23 11.6 0.0 3.4 4 0 0 4 4 4 0 ER protein Pkr1 N2227 PF07942.12 CAR27380.1 - 1.8e-89 299.5 0.1 2.3e-89 299.2 0.1 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 CAR27380.1 - 0.0046 17.7 0.0 0.018 15.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR27380.1 - 0.0087 16.7 0.0 0.088 13.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR27380.1 - 0.12 12.2 0.0 0.62 9.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Ras PF00071.22 CAR27381.1 - 7.2e-60 201.3 0.0 8.5e-60 201.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR27381.1 - 2.1e-35 121.5 0.0 2.9e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR27381.1 - 3.9e-17 62.2 0.0 4.4e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR27381.1 - 4.1e-07 29.6 0.0 5.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR27381.1 - 2.9e-05 24.1 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR27381.1 - 7.3e-05 22.4 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CAR27381.1 - 0.00022 21.2 0.1 0.15 12.0 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CAR27381.1 - 0.14 12.5 0.1 0.25 11.7 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain PP2C PF00481.21 CAR27382.1 - 1.8e-46 158.9 0.0 3.7e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Period_C PF12114.8 CAR27382.1 - 1.1 8.9 3.8 2 8.0 3.8 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DFRP_C PF16543.5 CAR27383.1 - 9.3e-24 83.8 6.8 9.3e-24 83.8 6.8 3.7 3 1 1 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 CAR27383.1 - 8e-07 29.7 13.0 1.5e-05 25.7 3.2 3.6 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 CAR27383.1 - 2.4e-05 24.2 4.0 2.4e-05 24.2 4.0 3.2 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 CAR27383.1 - 0.00024 20.8 7.4 0.015 15.0 1.0 3.4 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH PF00642.24 CAR27383.1 - 0.0012 18.7 0.3 0.0012 18.7 0.3 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 CAR27383.1 - 0.077 13.5 11.1 0.63 10.6 2.5 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CAR27383.1 - 0.37 11.0 5.1 1.6 9.0 0.9 2.8 1 1 1 2 2 2 0 Zinc-finger containing family DUF2183 PF09949.9 CAR27384.1 - 2e-30 105.0 0.0 5.3e-30 103.7 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 CAR27384.1 - 0.0091 15.5 0.0 0.027 13.9 0.0 1.7 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) tRNA-synt_2d PF01409.20 CAR27385.1 - 1.8e-44 152.0 0.1 1.6e-25 90.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CAR27385.1 - 9.6e-25 86.8 0.1 2.4e-24 85.6 0.1 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain FAD_binding_1 PF00667.20 CAR27386.1 - 6.6e-27 94.5 0.0 1.3e-26 93.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CAR27386.1 - 1.2e-21 77.5 0.0 2.7e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CAR27386.1 - 6.5e-11 42.8 0.0 2.1e-10 41.2 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ATG11 PF10377.9 CAR27387.1 - 1.7e-42 144.5 0.7 1.7e-42 144.5 0.7 3.2 3 0 0 3 3 3 1 Autophagy-related protein 11 DtxR PF18357.1 CAR27387.1 - 0.61 9.8 2.8 1.9 8.2 2.8 1.9 1 0 0 1 1 1 0 Diphteria toxin repressor SH3 domain GTP-bdg_M PF16360.5 CAR27387.1 - 8.2 7.1 13.0 21 5.8 1.2 3.7 2 2 0 2 2 2 0 GTP-binding GTPase Middle Region Acetyltransf_1 PF00583.25 CAR27388.1 - 1.5e-17 63.9 0.0 1.8e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CAR27388.1 - 2.3e-10 40.8 0.0 3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CAR27388.1 - 2e-09 37.5 0.0 2.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAR27388.1 - 1.5e-07 31.3 0.1 2.4e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CAR27388.1 - 3.9e-05 24.3 0.0 4.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CAR27388.1 - 5.1e-05 23.3 0.0 9.9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CAR27388.1 - 8.4e-05 22.3 0.0 0.00012 21.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CAR27388.1 - 0.011 15.2 0.1 0.04 13.4 0.1 1.8 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 CAR27388.1 - 0.014 15.5 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PCNA_N PF00705.18 CAR27389.1 - 1.7e-54 182.9 1.7 3.3e-54 182.0 1.7 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CAR27389.1 - 1.3e-51 174.1 0.1 6.2e-51 171.9 0.1 1.9 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 CAR27389.1 - 1.2e-06 27.9 0.4 2.5e-05 23.5 0.2 2.0 1 1 1 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 CAR27389.1 - 0.0009 18.8 0.1 0.0011 18.5 0.1 1.2 1 0 0 1 1 1 1 Rad9 Histone PF00125.24 CAR27389.1 - 0.031 14.6 0.0 0.2 12.0 0.0 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 HMG_box PF00505.19 CAR27390.1 - 1.6e-25 89.3 0.6 2.5e-25 88.7 0.6 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CAR27390.1 - 1.8e-17 63.7 0.5 2.7e-17 63.1 0.5 1.3 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 CAR27390.1 - 0.0013 19.3 1.9 0.0042 17.6 0.0 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 CAR27390.1 - 0.023 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.13 CAR27390.1 - 0.079 13.5 0.7 0.079 13.5 0.7 1.5 1 1 1 2 2 2 0 YABBY protein zf-Tim10_DDP PF02953.15 CAR27391.1 - 1.5e-15 56.5 0.0 2e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TTL PF03133.15 CAR27392.1 - 6.1e-75 252.1 0.2 8.6e-75 251.6 0.2 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 CAR27392.1 - 3.6e-46 157.4 0.0 5.8e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 CAR27392.1 - 0.094 11.9 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 YheC/D like ATP-grasp RXT2_N PF08595.11 CAR27393.1 - 1.9e-38 131.9 0.9 1.9e-38 131.9 0.9 2.1 2 0 0 2 2 2 1 RXT2-like, N-terminal DUF3461 PF11944.8 CAR27393.1 - 0.012 15.7 0.7 0.022 14.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) Importin_rep_6 PF18829.1 CAR27393.1 - 0.025 14.7 2.6 0.9 9.7 0.6 2.5 2 0 0 2 2 2 0 Importin repeat 6 4HBT_2 PF13279.6 CAR27394.1 - 8.5e-08 32.7 0.0 1.4e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.25 CAR27395.1 - 1e-60 205.3 0.0 1.6e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27395.1 - 4.8e-30 104.7 0.0 6.9e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR27395.1 - 3.1e-05 23.1 0.1 4.3e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CAR27395.1 - 0.057 12.5 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 CAR27396.1 - 1.6e-25 89.9 0.0 3.4e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 CAR27396.1 - 2.6e-10 39.6 4.7 0.17 12.2 0.0 6.6 6 0 0 6 6 6 2 HEAT repeat Pkinase_Tyr PF07714.17 CAR27396.1 - 5.1e-10 39.1 0.0 8.7e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 CAR27396.1 - 3.7e-06 27.2 0.0 0.024 15.0 0.0 3.2 3 1 0 3 3 3 2 HEAT repeats Cnd1 PF12717.7 CAR27396.1 - 1.8e-05 24.8 1.7 0.024 14.7 0.1 3.8 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CAR27396.1 - 0.00011 20.9 5.3 0.023 13.3 5.2 2.5 1 1 0 1 1 1 1 Adaptin N terminal region Kinase-like PF14531.6 CAR27396.1 - 0.00044 19.6 0.0 0.0014 18.0 0.0 1.9 1 0 0 1 1 1 1 Kinase-like IFRD PF05004.13 CAR27396.1 - 0.0021 17.2 0.0 0.01 15.0 0.0 2.1 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) WD40 PF00400.32 CAR27396.1 - 0.004 18.0 1.9 3.5 8.6 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat HEAT_EZ PF13513.6 CAR27396.1 - 0.0062 17.0 0.9 6.2 7.4 0.0 3.6 3 0 0 3 3 3 1 HEAT-like repeat RasGEF_N_2 PF14663.6 CAR27396.1 - 0.019 15.4 1.0 2 8.9 0.0 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Sec8_exocyst PF04048.14 CAR27397.1 - 1.6e-46 157.7 6.0 1.6e-46 157.7 6.0 2.8 3 1 1 4 4 4 1 Sec8 exocyst complex component specific domain Sec5 PF15469.6 CAR27397.1 - 4.1e-05 23.5 6.5 0.0045 16.8 1.9 3.0 2 0 0 2 2 2 2 Exocyst complex component Sec5 CK2S PF15011.6 CAR27397.1 - 0.27 11.1 2.6 0.99 9.3 0.1 3.1 2 1 1 3 3 3 0 Casein Kinase 2 substrate Myf5 PF12232.8 CAR27397.1 - 0.97 10.3 3.5 2.9 8.7 0.8 2.9 3 0 0 3 3 3 0 Myogenic determination factor 5 ERCC4 PF02732.15 CAR27398.1 - 1.8e-08 34.8 2.9 1.8e-08 34.8 2.9 2.1 1 1 1 2 2 2 1 ERCC4 domain Fes1 PF08609.10 CAR27399.1 - 4.1e-24 85.3 3.0 1.1e-23 83.9 0.8 2.7 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 Arm PF00514.23 CAR27399.1 - 0.0011 18.9 0.1 1.5 8.9 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CAR27399.1 - 0.0032 17.6 0.0 4.1 7.9 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat V-ATPase_H_C PF11698.8 CAR27399.1 - 0.012 15.7 0.8 5.2 7.2 0.0 2.7 2 1 1 3 3 3 0 V-ATPase subunit H IBN_N PF03810.19 CAR27399.1 - 0.014 15.3 0.2 0.18 11.7 0.0 2.7 2 2 1 3 3 3 0 Importin-beta N-terminal domain DBB PF14545.6 CAR27399.1 - 0.019 14.9 0.1 0.038 13.9 0.1 1.5 1 0 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, DRIM PF07539.12 CAR27399.1 - 0.032 12.6 1.6 3 6.0 0.1 2.3 1 1 0 2 2 2 0 Down-regulated in metastasis TAF1_subA PF14929.6 CAR27399.1 - 0.038 13.4 0.1 0.065 12.6 0.1 1.5 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A Atx10homo_assoc PF09759.9 CAR27399.1 - 0.064 13.3 0.5 1.3 9.1 0.0 2.6 1 1 2 3 3 3 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 CAR27399.1 - 0.1 13.1 0.0 2.3 8.8 0.0 2.6 2 0 0 2 2 2 0 HEAT-like repeat Exo84_C PF16528.5 CAR27400.1 - 3.1e-67 226.4 4.3 3.1e-67 226.4 4.3 2.2 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CAR27400.1 - 1.5e-11 44.2 1.3 5.6e-11 42.4 1.3 2.0 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 CAR27400.1 - 0.0011 19.1 5.1 0.018 15.1 0.3 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 ANAPC4 PF12896.7 CAR27400.1 - 0.0036 16.8 10.8 0.19 11.2 0.1 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 4 SPARC_Ca_bdg PF10591.9 CAR27400.1 - 0.058 13.7 3.1 0.85 10.0 0.3 2.8 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region tRNA-Thr_ED PF08915.11 CAR27400.1 - 0.067 13.3 0.3 0.62 10.1 0.0 2.5 2 0 0 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase COG5 PF10392.9 CAR27400.1 - 0.11 12.6 9.1 0.064 13.4 5.0 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 FUSC PF04632.12 CAR27400.1 - 0.29 9.6 2.8 0.35 9.3 0.5 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family WD40 PF00400.32 CAR27401.1 - 5.9e-19 68.1 10.7 0.00035 21.3 0.0 7.7 8 1 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27401.1 - 1.8e-11 44.1 3.0 2e-06 28.0 0.0 5.9 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR27401.1 - 6.7e-08 32.6 2.2 0.00033 20.6 0.2 4.2 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CAR27401.1 - 1.2e-06 28.1 0.1 0.0022 17.4 0.0 2.5 2 1 0 2 2 2 2 WD40-like domain LisH PF08513.11 CAR27401.1 - 5.4e-05 23.0 0.1 0.00013 21.8 0.1 1.7 1 0 0 1 1 1 1 LisH RAB3GAP2_N PF14655.6 CAR27401.1 - 0.00019 20.9 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus ELYS-bb PF16687.5 CAR27401.1 - 0.00065 18.4 0.0 0.26 9.9 0.0 2.1 2 0 0 2 2 2 2 beta-propeller of ELYS nucleoporin Nup160 PF11715.8 CAR27401.1 - 0.038 12.6 0.7 7.8 5.0 0.0 3.1 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Trnau1ap PF17654.1 CAR27401.1 - 0.052 14.4 0.3 0.11 13.3 0.3 1.5 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins Ge1_WD40 PF16529.5 CAR27401.1 - 0.064 12.2 0.1 3.9 6.3 0.0 2.9 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Tfb4 PF03850.14 CAR27402.1 - 8e-107 356.8 0.2 9.4e-107 356.6 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Rad50_zn_hook PF04423.14 CAR27402.1 - 0.14 12.1 0.5 0.46 10.4 0.2 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2 PF00096.26 CAR27403.1 - 0.024 15.1 7.0 2.4 8.8 0.1 3.5 2 1 2 4 4 4 0 Zinc finger, C2H2 type SIP1 PF04938.12 CAR27404.1 - 2.7e-05 24.0 0.2 0.00049 19.9 0.2 2.2 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Protoglobin PF11563.8 CAR27404.1 - 0.011 15.7 0.0 0.025 14.5 0.0 1.6 1 1 1 2 2 2 0 Protoglobin Mito_carr PF00153.27 CAR27405.1 - 4.2e-55 183.6 3.0 9.9e-21 73.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CM_2 PF01817.21 CAR27406.1 - 0.0046 17.3 0.0 1.3 9.4 0.0 3.0 3 1 0 3 3 3 2 Chorismate mutase type II DnaJ PF00226.31 CAR27407.1 - 3e-11 43.3 0.2 2e-10 40.6 0.2 2.1 1 1 0 1 1 1 1 DnaJ domain MafB19-deam PF14437.6 CAR27408.1 - 4.5e-19 68.6 0.0 5.8e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 CAR27408.1 - 5.5e-19 67.9 0.0 7.1e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 CAR27408.1 - 0.00017 21.7 0.0 0.00027 21.0 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 CAR27408.1 - 0.0018 18.4 0.0 0.0039 17.3 0.0 1.5 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 Bd3614-deam PF14439.6 CAR27408.1 - 0.0082 16.2 0.6 0.082 13.0 0.5 2.0 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC2 PF18772.1 CAR27408.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.5 2 0 0 2 2 2 0 APOBEC2 NAD2 PF18782.1 CAR27408.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.5 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 APOBEC_N PF08210.11 CAR27408.1 - 0.027 14.4 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain APOBEC4_like PF18774.1 CAR27408.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC3 PF18771.1 CAR27408.1 - 0.2 11.8 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 UPF0139 PF03669.13 CAR27409.1 - 0.0038 17.1 1.5 0.011 15.5 1.5 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) Vac_ImportDeg PF09783.9 CAR27410.1 - 2.2e-57 193.4 0.1 2.7e-57 193.1 0.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein HMG_box PF00505.19 CAR27411.1 - 1.4e-16 60.6 0.8 2.9e-16 59.6 0.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CAR27411.1 - 9e-08 32.6 0.5 1.5e-07 31.9 0.5 1.4 1 0 0 1 1 1 1 HMG-box domain Pho88 PF10032.9 CAR27412.1 - 4.7e-77 257.4 0.2 5.4e-77 257.2 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) ThiF PF00899.21 CAR27413.1 - 1.8e-49 168.3 0.1 2.1e-49 168.1 0.1 1.0 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CAR27413.1 - 0.011 15.8 0.1 0.054 13.5 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 CAR27413.1 - 0.048 14.2 0.1 0.081 13.5 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF5058 PF16481.5 CAR27413.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) Fe-S_biosyn PF01521.20 CAR27414.1 - 1.4e-11 44.6 3.0 3.2e-05 24.1 0.0 2.7 2 1 0 2 2 2 2 Iron-sulphur cluster biosynthesis LAT PF15234.6 CAR27414.1 - 0.13 12.0 0.2 0.16 11.6 0.2 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells QueF_N PF14819.6 CAR27415.1 - 0.074 13.4 0.0 0.2 12.0 0.0 1.8 1 1 1 2 2 2 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term Ish1 PF10281.9 CAR27415.1 - 0.12 12.7 1.6 21 5.5 0.8 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein AIM3 PF17096.5 CAR27416.1 - 5.3e-24 85.0 5.8 5.3e-24 85.0 5.8 9.5 6 2 1 8 8 8 2 Altered inheritance of mitochondria protein 3 EF-hand_1 PF00036.32 CAR27417.1 - 1.7e-30 102.3 4.4 1.4e-08 33.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CAR27417.1 - 4.9e-27 94.2 0.4 1.4e-14 54.3 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CAR27417.1 - 1.3e-25 87.0 3.6 5.6e-08 32.1 0.0 4.6 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CAR27417.1 - 7.4e-18 63.2 4.0 4.9e-07 28.9 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CAR27417.1 - 1.4e-17 63.3 5.5 3.3e-09 36.4 0.0 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CAR27417.1 - 9.7e-13 48.2 0.0 2e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CAR27417.1 - 2.6e-06 27.7 0.1 0.0018 18.5 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CAR27417.1 - 2.4e-05 24.6 0.1 0.29 11.5 0.0 2.4 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 CAR27417.1 - 0.00035 20.5 0.0 0.081 13.0 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 CAR27417.1 - 0.0018 18.2 0.3 0.0056 16.6 0.1 1.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CAR27417.1 - 0.0023 17.9 0.0 0.8 9.6 0.0 2.7 1 1 2 3 3 3 1 Caleosin related protein Dockerin_1 PF00404.18 CAR27417.1 - 0.004 17.3 0.3 0.7 10.1 0.3 2.5 1 1 1 2 2 2 1 Dockerin type I domain DUF853 PF05872.12 CAR27417.1 - 0.0046 15.6 0.2 0.061 11.9 0.2 2.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) TerB PF05099.13 CAR27417.1 - 0.015 15.3 0.1 0.21 11.6 0.0 2.2 1 1 0 2 2 2 0 Tellurite resistance protein TerB SurA_N_3 PF13624.6 CAR27417.1 - 0.016 15.0 0.4 0.58 9.9 0.2 2.0 1 1 1 2 2 2 0 SurA N-terminal domain RNA_pol_Rpb4 PF03874.16 CAR27417.1 - 0.075 13.4 0.9 0.8 10.0 0.1 2.4 2 1 0 2 2 2 0 RNA polymerase Rpb4 GPHH PF16905.5 CAR27417.1 - 0.081 12.7 0.0 0.88 9.4 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Glycos_trans_3N PF02885.17 CAR27417.1 - 0.13 12.2 2.9 4.7 7.1 0.0 3.3 1 1 1 2 2 2 0 Glycosyl transferase family, helical bundle domain Glycos_transf_1 PF00534.20 CAR27418.1 - 1.1e-09 38.0 0.0 2.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CAR27418.1 - 1.2e-06 29.0 0.0 0.00014 22.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CAR27418.1 - 7.8e-05 22.7 0.0 0.00015 21.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CAR27418.1 - 0.012 16.0 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Hist_deacetyl PF00850.19 CAR27419.1 - 3.1e-77 260.1 0.0 4.5e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Spermine_synth PF01564.17 CAR27420.1 - 8.3e-74 247.1 0.0 1.2e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CAR27420.1 - 2e-26 91.6 0.1 3.5e-26 90.9 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CAR27420.1 - 0.00035 21.2 0.0 0.00059 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR27420.1 - 0.0016 19.1 0.0 0.0064 17.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_30 PF05430.11 CAR27420.1 - 0.027 14.4 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 CAR27420.1 - 0.049 13.6 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Med1 PF10744.9 CAR27421.1 - 1.5e-29 103.3 9.8 8.8e-27 94.2 1.2 3.3 3 1 1 4 4 4 3 Mediator of RNA polymerase II transcription subunit 1 NUDIX PF00293.28 CAR27422.1 - 2.3e-15 56.8 0.0 6.4e-15 55.4 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain EnY2 PF10163.9 CAR27423.1 - 6.6e-23 80.9 1.4 7.6e-23 80.7 1.4 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 COMPASS-Shg1 PF05205.12 CAR27423.1 - 0.02 15.6 1.6 1.4 9.7 0.2 2.2 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF3874 PF12990.7 CAR27423.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.5 1 1 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) SecE PF00584.20 CAR27423.1 - 0.12 12.3 0.0 0.86 9.6 0.0 2.0 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex TPR_1 PF00515.28 CAR27424.1 - 2.5e-49 163.1 23.4 2.4e-07 30.3 0.0 10.9 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 CAR27424.1 - 2.3e-42 139.7 26.8 0.00013 21.8 0.0 10.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 CAR27424.1 - 1.6e-27 93.3 18.9 0.19 12.1 0.0 10.9 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 CAR27424.1 - 3e-25 86.7 33.0 4.4e-05 23.6 0.1 11.9 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_11 PF13414.6 CAR27424.1 - 4.9e-21 74.1 20.5 0.00033 20.3 0.0 9.5 4 3 6 10 10 10 6 TPR repeat TPR_12 PF13424.6 CAR27424.1 - 2.1e-19 69.6 32.6 0.00028 21.1 0.3 8.7 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 CAR27424.1 - 3.8e-18 65.8 37.6 4.6e-05 24.0 1.5 8.1 6 3 2 8 8 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 CAR27424.1 - 2.9e-17 61.4 24.8 0.00013 21.7 0.4 9.6 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 CAR27424.1 - 3.5e-17 61.6 45.4 0.0024 18.5 0.4 11.2 5 3 6 11 11 10 8 Tetratricopeptide repeat TPR_9 PF13371.6 CAR27424.1 - 8e-12 45.1 42.5 0.00017 21.7 0.0 7.7 4 1 2 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 CAR27424.1 - 8.3e-12 45.5 45.3 0.00012 22.5 0.9 8.8 5 4 3 8 8 7 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR27424.1 - 1.4e-07 31.6 21.4 0.00097 19.3 0.0 4.2 5 0 0 5 5 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CAR27424.1 - 2e-06 28.1 40.7 0.9 10.3 0.0 10.7 11 0 0 11 11 9 3 Tetratricopeptide repeat ChAPs PF09295.10 CAR27424.1 - 0.02 13.9 5.6 0.39 9.7 1.4 3.1 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 CAR27424.1 - 0.18 11.7 31.5 0.13 12.2 0.7 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat RPN7 PF10602.9 CAR27424.1 - 1.1 8.9 7.2 21 4.7 1.0 4.3 2 2 1 4 4 4 0 26S proteasome subunit RPN7 SNF2_N PF00176.23 CAR27425.1 - 6.9e-53 179.6 0.1 2.2e-52 177.9 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR27425.1 - 5e-15 55.8 0.0 4.4e-14 52.8 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR27425.1 - 3.1e-11 43.6 2.8 5.6e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CAR27425.1 - 3.5e-08 33.2 11.6 3.5e-08 33.2 11.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CAR27425.1 - 7.9e-08 32.3 0.0 1.8e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CAR27425.1 - 2.6e-05 24.0 1.5 8.5e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase zf-RING_UBOX PF13445.6 CAR27425.1 - 0.00021 21.2 6.6 0.00021 21.2 6.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR27425.1 - 0.00051 19.8 9.8 0.00051 19.8 9.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CAR27425.1 - 0.0006 19.9 10.2 0.0006 19.9 10.2 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING AAA_34 PF13872.6 CAR27425.1 - 0.00096 18.1 0.2 0.0062 15.5 0.2 2.2 2 1 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 MH2 PF03166.14 CAR27425.1 - 0.0051 17.1 0.0 0.028 14.7 0.0 2.2 1 1 0 1 1 1 1 MH2 domain zf-RING_2 PF13639.6 CAR27425.1 - 0.0065 16.8 10.1 0.0065 16.8 10.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CAR27425.1 - 0.0074 16.1 8.2 0.0074 16.1 8.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.6 CAR27425.1 - 0.017 15.1 3.3 0.017 15.1 3.3 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-rbx1 PF12678.7 CAR27425.1 - 0.02 15.2 5.8 0.02 15.2 5.8 2.2 2 0 0 2 2 1 0 RING-H2 zinc finger domain NAD_binding_4 PF07993.12 CAR27426.1 - 1.3e-71 240.8 0.0 1.8e-71 240.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CAR27426.1 - 1.2e-67 228.3 0.0 1.7e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CAR27426.1 - 1.2e-14 54.4 0.0 2.6e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 CAR27426.1 - 1.8e-11 44.0 0.0 3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Condensation PF00668.20 CAR27426.1 - 2.2e-08 33.2 0.6 3.5e-08 32.6 0.6 1.2 1 0 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.19 CAR27426.1 - 1.3e-06 27.6 0.0 3.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 CAR27426.1 - 0.00079 20.4 0.0 0.0049 17.8 0.0 2.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 CAR27426.1 - 0.0047 16.4 0.0 0.0084 15.5 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CAR27426.1 - 0.18 10.8 0.0 0.42 9.7 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Not3 PF04065.15 CAR27427.1 - 1.4e-63 214.4 37.8 9.4e-63 211.7 31.2 2.9 2 1 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CAR27427.1 - 1e-34 119.4 10.5 1e-34 119.4 10.5 2.5 2 1 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.13 CAR27427.1 - 8.5 6.9 12.8 0.51 10.8 2.7 3.6 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 LMWPc PF01451.21 CAR27428.1 - 2e-48 164.4 0.0 2.3e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Transketolase_N PF00456.21 CAR27429.1 - 8e-147 488.5 0.0 1.4e-146 487.8 0.0 1.4 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CAR27429.1 - 1.5e-46 158.3 0.0 3.2e-46 157.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CAR27429.1 - 8.8e-14 51.5 0.0 1.9e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 CAR27429.1 - 1.6e-05 24.1 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 CAR27429.1 - 0.00061 19.6 0.1 0.0032 17.3 0.1 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 CAR27429.1 - 0.017 14.4 0.0 0.032 13.4 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Opy2 PF09463.10 CAR27430.1 - 2.9e-09 37.1 21.1 4.3e-09 36.5 21.1 1.3 1 0 0 1 1 1 1 Opy2 protein FAM176 PF14851.6 CAR27430.1 - 0.0015 18.2 1.5 0.029 14.0 0.0 2.3 2 0 0 2 2 2 1 FAM176 family BUD22 PF09073.10 CAR27430.1 - 0.018 14.4 0.2 0.018 14.4 0.2 2.0 2 0 0 2 2 2 0 BUD22 Amnionless PF14828.6 CAR27430.1 - 0.03 13.2 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Amnionless Colicin_V PF02674.16 CAR27430.1 - 0.045 13.7 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Colicin V production protein DUF2207 PF09972.9 CAR27430.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Syndecan PF01034.20 CAR27430.1 - 0.15 12.0 0.2 0.29 11.1 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain PT-VENN PF04829.13 CAR27430.1 - 1.6 8.8 4.1 0.36 10.9 0.7 1.7 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif 5TM-5TMR_LYT PF07694.12 CAR27430.1 - 2.2 7.8 3.8 3.2 7.2 3.8 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF3074 PF11274.8 CAR27431.1 - 3.3e-25 89.1 0.0 4.2e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Peptidase_M32 PF02074.15 CAR27432.1 - 0.013 14.3 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase YopE_N PF09020.10 CAR27432.1 - 0.14 12.4 2.5 3.5 7.9 0.2 2.4 2 0 0 2 2 2 0 YopE, N terminal TIR PF01582.20 CAR27432.1 - 2.3 8.0 7.7 0.65 9.8 0.1 2.2 1 1 1 2 2 2 0 TIR domain CIMR PF00878.18 CAR27433.1 - 1.2e-09 38.4 1.2 4.5e-05 23.5 0.1 2.7 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 CAR27433.1 - 2e-07 30.4 0.0 2.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor PRKCSH_1 PF13015.6 CAR27433.1 - 2.8e-06 27.1 0.1 5.3e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 CAR27433.1 - 0.00089 19.2 0.3 0.0026 17.7 0.3 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 Ctr PF04145.15 CAR27433.1 - 0.022 15.4 0.0 0.64 10.6 0.0 2.2 2 0 0 2 2 2 0 Ctr copper transporter family Bac_export_2 PF01312.19 CAR27433.1 - 0.22 10.7 0.0 0.64 9.2 0.0 1.7 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family GTP_EFTU PF00009.27 CAR27434.1 - 1.5e-53 181.2 0.0 2.2e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CAR27434.1 - 3.5e-40 136.8 0.0 7e-40 135.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CAR27434.1 - 6.1e-15 55.4 1.9 2e-14 53.7 1.9 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAR27434.1 - 0.0023 18.0 0.1 0.049 13.7 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CAR27434.1 - 0.051 13.5 0.6 0.051 13.5 0.6 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 RRM_1 PF00076.22 CAR27435.1 - 2.8e-12 46.3 0.0 6.8e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.13 CAR27435.1 - 0.01 16.5 0.6 0.016 15.8 0.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PSD3 PF07626.11 CAR27436.1 - 0.078 13.5 0.1 1.7 9.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1587) HGTP_anticodon PF03129.20 CAR27437.1 - 3.9e-20 71.8 0.0 1.4e-19 70.0 0.0 2.0 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CAR27437.1 - 3.5e-06 27.1 0.0 1.4e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) DIM1 PF02966.16 CAR27438.1 - 6.1e-69 229.9 1.2 6.9e-69 229.7 1.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CAR27438.1 - 0.00013 21.9 0.1 0.00018 21.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin DUF3192 PF11399.8 CAR27438.1 - 0.039 13.9 0.1 0.06 13.3 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3192) Thioredoxin_8 PF13905.6 CAR27438.1 - 0.14 12.5 1.3 0.23 11.8 1.3 1.4 1 1 0 1 1 1 0 Thioredoxin-like Ribosomal_L31 PF01197.18 CAR27439.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 Tau95 PF09734.9 CAR27440.1 - 1.7e-35 122.8 0.7 4e-35 121.7 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CAR27440.1 - 1.4e-24 86.7 0.0 2.6e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain fn3_6 PF17766.1 CAR27440.1 - 0.084 13.1 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Fibronectin type-III domain XPC-binding PF09280.11 CAR27440.1 - 0.18 11.5 0.0 0.46 10.2 0.0 1.6 1 0 0 1 1 1 0 XPC-binding domain PP2C PF00481.21 CAR27441.1 - 1.1e-59 202.2 0.0 5.7e-56 190.0 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C DUF658 PF04936.12 CAR27441.1 - 0.015 15.1 0.2 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF658) Plus-3 PF03126.18 CAR27441.1 - 0.15 12.6 0.0 0.36 11.4 0.0 1.6 1 0 0 1 1 1 0 Plus-3 domain Glyco_transf_20 PF00982.21 CAR27442.1 - 2.3e-198 659.7 0.0 2.6e-198 659.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 CAR27442.1 - 0.0022 17.6 0.4 0.094 12.2 0.1 2.9 2 1 0 2 2 2 1 Glycosyl transferases group 1 ATP-synt_ab PF00006.25 CAR27444.1 - 4.3e-67 225.9 0.0 5.8e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CAR27444.1 - 1e-14 54.7 0.7 2.1e-14 53.8 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Atg14 PF10186.9 CAR27445.1 - 2.5e-53 181.3 4.2 3.2e-53 180.9 4.2 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 CAR27445.1 - 0.0066 15.1 5.7 0.0095 14.6 5.7 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A MMR_HSR1 PF01926.23 CAR27446.1 - 0.0014 18.7 0.1 0.57 10.3 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CAR27446.1 - 0.0077 16.3 0.2 0.33 11.0 0.2 2.2 2 0 0 2 2 2 1 Dynamin family Ras PF00071.22 CAR27446.1 - 0.072 12.7 0.0 0.82 9.2 0.0 2.2 2 0 0 2 2 2 0 Ras family TylF PF05711.11 CAR27446.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) WD40 PF00400.32 CAR27447.1 - 0.065 14.1 3.4 5.5 8.0 0.0 4.4 4 1 0 4 4 4 0 WD domain, G-beta repeat PH PF00169.29 CAR27448.1 - 8.9e-09 35.8 9.4 0.00035 21.0 1.0 3.0 3 1 0 3 3 3 2 PH domain PH_11 PF15413.6 CAR27448.1 - 0.0036 17.7 3.8 0.9 10.0 0.3 3.6 3 1 1 4 4 4 2 Pleckstrin homology domain SHE3 PF17078.5 CAR27449.1 - 6.5e-86 287.7 37.0 8.5e-86 287.3 37.0 1.1 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Bap31_Bap29_C PF18035.1 CAR27449.1 - 9.8e-05 22.3 1.4 9.8e-05 22.3 1.4 2.7 2 1 1 3 3 3 1 Bap31/Bap29 cytoplasmic coiled-coil domain Filament PF00038.21 CAR27449.1 - 0.0034 17.0 25.9 0.0062 16.2 25.9 1.3 1 0 0 1 1 1 1 Intermediate filament protein GAS PF13851.6 CAR27449.1 - 0.026 13.9 35.2 0.18 11.1 20.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 CAR27449.1 - 0.33 10.2 28.6 0.23 10.7 10.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 CAR27449.1 - 0.4 9.5 29.8 0.085 11.7 25.1 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 CAR27449.1 - 0.48 10.2 20.4 0.31 10.8 11.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) HrpB7 PF09486.10 CAR27449.1 - 7 7.0 12.1 2 8.8 8.8 1.8 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) TFIIB PF00382.19 CAR27450.1 - 2.8e-36 123.4 1.1 4.1e-24 84.4 0.8 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CAR27450.1 - 1.6e-12 46.8 2.2 2.7e-12 46.0 2.2 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding SRP54 PF00448.22 CAR27451.1 - 2.2e-78 262.4 1.7 1.8e-77 259.4 0.6 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CAR27451.1 - 2.9e-29 101.6 9.2 2.9e-29 101.6 9.2 4.0 4 0 0 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 CAR27451.1 - 1.9e-14 53.6 3.6 5.2e-14 52.2 3.6 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CAR27451.1 - 1.8e-05 24.4 2.5 0.00011 21.8 0.9 2.8 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 CAR27451.1 - 0.00017 21.6 0.0 0.00058 19.9 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 CAR27451.1 - 0.0002 21.5 0.2 0.00083 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CAR27451.1 - 0.0011 19.4 1.0 0.0033 17.8 0.1 2.3 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 CAR27451.1 - 0.0017 17.4 0.9 0.0064 15.5 0.2 2.3 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 CAR27451.1 - 0.002 17.6 5.0 2.2 7.7 0.1 4.1 3 1 1 4 4 4 1 Signal recognition particle receptor beta subunit MobB PF03205.14 CAR27451.1 - 0.0028 17.5 0.3 0.0083 16.0 0.0 2.0 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 CAR27451.1 - 0.0067 17.0 0.0 0.029 14.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain MipZ PF09140.11 CAR27451.1 - 0.014 14.7 0.1 3.2 7.0 0.0 2.6 2 0 0 2 2 2 0 ATPase MipZ AAA_31 PF13614.6 CAR27451.1 - 0.019 14.9 0.9 0.051 13.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 CAR27451.1 - 0.028 14.3 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.29 CAR27451.1 - 0.031 14.7 2.5 0.12 12.8 0.6 2.8 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CAR27451.1 - 0.042 13.1 0.0 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin CLP1_P PF16575.5 CAR27451.1 - 0.045 13.6 0.3 6.6 6.5 0.1 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 CAR27451.1 - 0.045 13.5 1.3 0.067 12.9 0.0 2.0 3 0 0 3 3 2 0 AAA domain VirE PF05272.11 CAR27451.1 - 0.045 13.5 0.2 0.12 12.1 0.0 1.8 2 0 0 2 2 1 0 Virulence-associated protein E AAA_16 PF13191.6 CAR27451.1 - 0.051 14.0 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CAR27451.1 - 0.061 13.6 0.2 0.42 10.9 0.1 2.5 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 CAR27451.1 - 0.072 12.8 0.0 0.072 12.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CAR27451.1 - 0.083 13.1 0.1 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CAR27451.1 - 0.13 12.3 2.0 0.42 10.7 0.1 2.7 3 1 0 3 3 3 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CAR27451.1 - 0.16 11.8 2.1 3.5 7.5 2.1 2.6 1 1 0 1 1 1 0 NTPase DUF1398 PF07166.11 CAR27451.1 - 0.4 10.7 2.3 64 3.6 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1398) G-alpha PF00503.20 CAR27451.1 - 0.52 9.4 5.5 1.2 8.2 0.1 3.0 2 1 1 3 3 3 0 G-protein alpha subunit ArsA_ATPase PF02374.15 CAR27451.1 - 3.4 6.8 17.3 0.38 9.9 0.1 4.1 5 0 0 5 5 5 0 Anion-transporting ATPase DUF1712 PF08217.11 CAR27452.1 - 1.8e-136 456.1 0.0 2.7e-119 399.4 0.0 2.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) AA_permease PF00324.21 CAR27453.1 - 6e-125 417.5 24.9 6.8e-125 417.4 24.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR27453.1 - 1.4e-21 76.9 27.6 1.9e-21 76.4 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease Synaptobrevin PF00957.21 CAR27453.1 - 0.044 13.6 0.5 0.9 9.4 0.0 2.9 3 0 0 3 3 3 0 Synaptobrevin DIL PF01843.19 CAR27454.1 - 2.9e-18 66.0 6.3 1e-16 61.1 6.3 2.7 1 1 0 1 1 1 1 DIL domain Ank_5 PF13857.6 CAR27454.1 - 7.8e-11 42.0 0.2 8.1e-07 29.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR27454.1 - 0.00072 20.1 0.0 0.0016 19.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Nop53 PF07767.11 CAR27454.1 - 0.075 12.4 6.0 0.14 11.5 6.0 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GP67 PF17634.2 CAR27454.1 - 0.39 11.1 14.2 1.3 9.5 14.2 1.8 1 0 0 1 1 1 0 Gene product 67 RXT2_N PF08595.11 CAR27454.1 - 0.4 10.7 10.0 8.1 6.5 6.7 2.5 2 0 0 2 2 2 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 CAR27454.1 - 2.2 8.7 10.4 5.8 7.4 10.4 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PRMT5_TIM PF17285.2 CAR27455.1 - 3.8e-72 242.6 3.2 6.9e-72 241.7 2.5 1.8 2 0 0 2 2 2 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 CAR27455.1 - 1.8e-59 200.5 0.0 3.1e-59 199.7 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CAR27455.1 - 6.1e-59 198.9 2.0 6.9e-59 198.7 0.7 1.8 2 0 0 2 2 2 1 PRMT5 oligomerisation domain GP120 PF00516.18 CAR27455.1 - 0.053 12.1 0.2 0.099 11.2 0.2 1.3 1 0 0 1 1 1 0 Envelope glycoprotein GP120 CKS PF01111.19 CAR27456.1 - 1.2e-33 115.2 0.1 1.8e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Med3 PF11593.8 CAR27456.1 - 5.4 6.1 10.4 6.5 5.8 10.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PI3_PI4_kinase PF00454.27 CAR27457.1 - 5.1e-56 190.3 0.1 1.9e-55 188.4 0.1 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 CAR27457.1 - 3.4e-25 87.9 6.5 1.4e-24 85.9 1.0 4.4 4 0 0 4 4 4 1 UME (NUC010) domain FATC PF02260.20 CAR27457.1 - 9e-12 44.6 0.1 2e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 CAR27457.1 - 2.5e-05 23.6 5.0 6.6e-05 22.3 3.4 2.7 2 1 0 2 2 2 1 FAT domain TPR_19 PF14559.6 CAR27457.1 - 0.034 14.7 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAR27457.1 - 0.036 14.9 0.0 0.16 12.9 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3106 PF11304.8 CAR27457.1 - 0.21 12.1 3.2 0.39 11.2 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) MMM1 PF10296.9 CAR27458.1 - 2.2e-11 43.4 0.1 2.2e-11 43.4 0.1 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 CAR27458.1 - 9e-05 22.8 0.5 0.00034 21.0 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain LsmAD PF06741.13 CAR27458.1 - 5.9 7.5 8.5 0.78 10.3 0.2 2.6 2 0 0 2 2 2 0 LsmAD domain Cofilin_ADF PF00241.20 CAR27460.1 - 7.9e-27 93.5 0.0 7.1e-13 48.4 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF2341 PF10102.9 CAR27460.1 - 0.13 12.9 0.0 3.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2341) zf-RING_2 PF13639.6 CAR27461.1 - 1.1e-10 41.6 25.3 7.3e-10 39.0 7.2 2.5 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 CAR27461.1 - 8.9e-07 28.7 6.2 8.9e-07 28.7 6.2 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR27461.1 - 1.7e-06 27.8 5.1 1.7e-06 27.8 5.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAR27461.1 - 2.6e-05 23.8 1.1 2.6e-05 23.8 1.1 3.2 3 1 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 CAR27461.1 - 9.2e-05 22.7 7.9 9.2e-05 22.7 7.9 3.1 2 2 1 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CAR27461.1 - 0.00019 21.4 1.5 0.00019 21.4 1.5 3.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CAR27461.1 - 0.00031 20.5 3.5 0.00031 20.5 3.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CAR27461.1 - 0.0075 16.3 2.2 0.0075 16.3 2.2 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prominin PF05478.11 CAR27461.1 - 0.014 13.4 0.0 0.019 12.9 0.0 1.1 1 0 0 1 1 1 0 Prominin Zf_RING PF16744.5 CAR27461.1 - 0.02 15.0 5.2 0.02 15.0 5.2 3.3 2 1 1 3 3 3 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 CAR27461.1 - 0.034 13.8 18.5 0.24 11.0 3.4 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CAR27461.1 - 0.037 14.0 6.1 0.037 14.0 6.1 3.2 2 2 1 3 3 3 0 zinc-RING finger domain PHD PF00628.29 CAR27461.1 - 0.26 11.2 23.4 0.2 11.6 10.6 2.7 2 1 0 2 2 2 0 PHD-finger EURL PF06937.11 CAR27461.1 - 0.57 9.5 6.5 4.4 6.7 0.6 2.6 2 1 0 2 2 2 0 EURL protein Prok-RING_4 PF14447.6 CAR27461.1 - 3.9 7.4 24.0 0.53 10.2 9.6 3.4 2 2 1 3 3 3 0 Prokaryotic RING finger family 4 RINGv PF12906.7 CAR27461.1 - 5.2 7.3 22.1 0.098 12.8 3.3 2.6 2 1 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 CAR27461.1 - 7.7 6.8 20.8 0.12 12.5 2.2 3.2 2 2 1 3 3 3 0 FANCL C-terminal domain PHF5 PF03660.14 CAR27462.1 - 3.1e-51 171.9 12.0 3.5e-51 171.8 12.0 1.0 1 0 0 1 1 1 1 PHF5-like protein Sec7 PF01369.20 CAR27463.1 - 4.6e-26 91.6 0.9 7.7e-26 90.9 0.9 1.3 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 CAR27463.1 - 0.1 13.1 0.3 3.2 8.3 0.3 3.0 1 1 0 1 1 1 0 PH domain DUF3818 PF12825.7 CAR27464.1 - 4.6e-127 423.7 6.7 7.9e-127 422.9 6.7 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CAR27464.1 - 1.3e-38 131.9 0.8 1.3e-38 131.9 0.8 2.0 2 0 0 2 2 2 1 PX-associated PX PF00787.24 CAR27464.1 - 1.2e-11 44.6 0.1 1e-10 41.6 0.0 2.8 3 1 0 3 3 3 1 PX domain AflR PF08493.10 CAR27464.1 - 0.54 9.7 5.5 1 8.7 5.5 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein SLX9 PF15341.6 CAR27465.1 - 8e-23 81.3 13.9 8e-23 81.3 13.9 1.6 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 MAS20 PF02064.15 CAR27466.1 - 1.2e-38 132.1 0.3 1.2e-38 132.1 0.3 1.3 2 0 0 2 2 2 1 MAS20 protein import receptor FAM110_N PF14161.6 CAR27466.1 - 0.017 15.3 0.4 0.027 14.7 0.4 1.4 1 0 0 1 1 1 0 Centrosome-associated N terminus PAP_PilO PF06864.12 CAR27466.1 - 0.043 12.6 0.2 0.076 11.8 0.0 1.4 2 0 0 2 2 2 0 Pilin accessory protein (PilO) DUF4149 PF13664.6 CAR27467.1 - 5e-21 74.9 0.6 7.1e-21 74.4 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) L51_S25_CI-B8 PF05047.16 CAR27468.1 - 6.3e-14 51.6 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain IF-2B PF01008.17 CAR27469.1 - 1.8e-102 342.4 0.1 1.8e-102 342.4 0.1 1.5 2 0 0 2 2 2 1 Initiation factor 2 subunit family DeoRC PF00455.22 CAR27469.1 - 0.0089 16.0 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 DeoR C terminal sensor domain EutQ PF06249.12 CAR27469.1 - 5.7 6.7 6.0 1.7 8.4 0.9 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation protein EutQ CDC45 PF02724.14 CAR27469.1 - 6.3 5.0 15.9 31 2.7 15.4 2.0 2 0 0 2 2 2 0 CDC45-like protein BCAS2 PF05700.11 CAR27471.1 - 5e-05 23.1 9.6 0.0001 22.1 9.6 1.7 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) LupA PF18242.1 CAR27471.1 - 0.036 13.7 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain Hrs_helical PF12210.8 CAR27471.1 - 0.18 12.4 3.0 0.17 12.5 1.0 1.9 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Importin_rep_2 PF18786.1 CAR27471.1 - 0.76 9.7 4.7 12 5.8 0.1 2.9 3 0 0 3 3 3 0 Importin 13 repeat HALZ PF02183.18 CAR27471.1 - 1.5 9.1 6.3 0.25 11.6 0.9 2.5 3 0 0 3 3 3 0 Homeobox associated leucine zipper Ribosomal_L5_C PF00673.21 CAR27472.1 - 3.6e-22 78.3 0.0 5.6e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CAR27472.1 - 3.5e-18 65.7 0.0 1e-17 64.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CAR27472.1 - 0.0022 17.7 0.2 0.0049 16.5 0.2 1.5 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain ApbA PF02558.16 CAR27472.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Proteasome PF00227.26 CAR27473.1 - 8.1e-47 159.2 0.2 1e-46 158.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Forkhead PF00250.18 CAR27474.1 - 7.5e-26 90.2 0.3 1.2e-24 86.3 0.0 2.6 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 CAR27474.1 - 2.8e-13 50.0 0.4 4.6e-12 46.1 0.5 2.5 2 0 0 2 2 2 1 FHA domain Linker_histone PF00538.19 CAR27474.1 - 0.012 15.9 0.1 2 8.8 0.0 3.0 2 0 0 2 2 2 0 linker histone H1 and H5 family COG4 PF08318.12 CAR27475.1 - 6.2e-84 281.9 4.2 1.1e-83 281.2 4.2 1.4 1 0 0 1 1 1 1 COG4 transport protein DUF2700 PF10912.8 CAR27475.1 - 0.064 13.3 0.1 0.15 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2700) T4SS PF07996.11 CAR27475.1 - 0.067 13.6 14.5 0.085 13.3 1.1 2.5 2 1 0 2 2 2 0 Type IV secretion system proteins APT PF03440.14 CAR27475.1 - 0.13 12.3 0.1 0.37 10.8 0.1 1.8 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain Vps51 PF08700.11 CAR27475.1 - 0.62 10.2 0.0 0.62 10.2 0.0 3.9 4 1 0 5 5 5 0 Vps51/Vps67 Pil1 PF13805.6 CAR27476.1 - 1.4e-123 411.6 0.4 2.1e-123 411.0 0.1 1.4 2 0 0 2 2 2 1 Eisosome component PIL1 SLT_beta PF02258.16 CAR27476.1 - 0.028 14.4 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Shiga-like toxin beta subunit zf-CCCH PF00642.24 CAR27477.1 - 3.4e-13 49.1 28.8 0.00083 19.2 0.4 5.6 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAR27477.1 - 4e-11 42.6 30.0 6.6e-06 26.0 2.5 5.4 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 CAR27477.1 - 1e-08 35.9 22.1 0.0032 18.2 0.5 5.2 1 1 4 5 5 5 4 Torus domain zf-CCCH_3 PF15663.5 CAR27477.1 - 5e-06 26.7 7.4 5e-06 26.7 7.4 2.2 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 CAR27477.1 - 0.029 14.2 1.3 0.029 14.2 1.3 5.1 5 1 0 5 5 5 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CAR27477.1 - 0.055 14.0 21.9 0.61 10.6 1.1 4.9 4 1 0 4 4 4 0 RNA-binding, Nab2-type zinc finger RPN7 PF10602.9 CAR27478.1 - 1.2e-54 184.6 2.9 1.2e-54 184.6 2.9 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 CAR27478.1 - 9.7e-14 51.8 0.0 6.1e-13 49.2 0.0 2.4 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CAR27478.1 - 0.00083 19.3 1.2 0.061 13.5 0.4 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAR27478.1 - 0.0021 18.3 0.6 0.15 12.4 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CAR27478.1 - 0.0029 17.5 0.8 1.5 9.0 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAR27478.1 - 0.009 16.8 0.0 5.9 8.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR27478.1 - 0.016 15.4 1.0 0.045 14.0 0.2 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_15 PF13429.6 CAR27478.1 - 0.017 14.3 0.2 0.047 12.9 0.2 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat MIOX PF05153.15 CAR27478.1 - 0.036 13.6 0.1 0.088 12.4 0.1 1.6 1 0 0 1 1 1 0 Myo-inositol oxygenase DUF357 PF04010.13 CAR27478.1 - 0.083 13.0 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Interferon PF00143.19 CAR27478.1 - 0.088 13.0 0.8 0.18 12.0 0.8 1.4 1 0 0 1 1 1 0 Interferon alpha/beta domain TPR_16 PF13432.6 CAR27478.1 - 0.17 12.5 0.0 6.5 7.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAR27478.1 - 0.26 11.2 0.7 12 5.9 0.1 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAR27478.1 - 0.51 10.3 5.0 0.49 10.3 0.7 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Catalase PF00199.19 CAR27479.1 - 1e-164 548.2 0.5 2.5e-164 547.0 0.5 1.6 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CAR27479.1 - 6e-14 52.0 0.0 2.2e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive Arc_C PF18162.1 CAR27479.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Arc C-lobe ELO PF01151.18 CAR27480.1 - 5.8e-61 206.2 23.5 7e-61 205.9 23.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family RNase_PH PF01138.21 CAR27481.1 - 4.8e-25 88.6 0.0 1.2e-24 87.3 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 PfkB PF00294.24 CAR27482.1 - 4.5e-47 160.8 5.0 2e-46 158.7 5.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase AAA_8 PF12780.7 CAR27482.1 - 0.031 13.6 0.1 0.053 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 MoCF_biosynth PF00994.24 CAR27482.1 - 0.045 13.4 0.1 0.083 12.5 0.1 1.4 1 0 0 1 1 1 0 Probable molybdopterin binding domain UCH PF00443.29 CAR27483.1 - 1.8e-77 260.3 0.0 3.4e-77 259.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR27483.1 - 5.3e-16 59.1 7.7 6.1e-07 29.3 1.2 3.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CAR27483.1 - 0.00023 21.7 0.1 0.00023 21.7 0.1 3.0 3 0 0 3 3 3 1 DUSP domain USP7_C2 PF14533.6 CAR27483.1 - 0.0014 18.4 0.5 0.0069 16.1 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal CW_binding_1 PF01473.20 CAR27483.1 - 0.41 11.1 3.0 2.1 8.8 3.0 2.3 1 0 0 1 1 1 0 Putative cell wall binding repeat SPX PF03105.19 CAR27484.1 - 7.1e-52 177.6 3.3 1e-51 177.1 3.3 1.3 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.19 CAR27484.1 - 1.7e-28 99.9 35.2 2.4e-28 99.4 35.2 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 CAR27484.1 - 3.8e-23 82.1 46.7 2.3e-19 69.7 25.1 2.3 2 1 1 3 3 3 2 Citrate transporter Aconitase PF00330.20 CAR27485.1 - 1e-148 496.2 0.0 1.3e-148 495.8 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CAR27485.1 - 6.8e-44 149.4 0.0 1.3e-43 148.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RasGEF PF00617.19 CAR27486.1 - 6.5e-43 147.0 0.1 2e-42 145.4 0.1 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CAR27486.1 - 1.4e-14 54.2 0.3 7e-14 51.9 0.3 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 CAR27486.1 - 7.9e-06 25.4 0.0 1.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR27486.1 - 0.0034 17.2 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CAR27486.1 - 0.0065 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CRAL_TRIO_2 PF13716.6 CAR27487.1 - 7.7e-27 94.1 0.4 1.9e-26 92.9 0.4 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 CAR27487.1 - 1.2e-08 34.9 1.0 3.7e-08 33.3 0.3 2.2 2 0 0 2 2 2 1 RhoGAP domain DUF4522 PF15022.6 CAR27487.1 - 0.11 12.7 0.1 3.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) PRP21_like_P PF12230.8 CAR27488.1 - 2.4e-33 115.8 8.2 1.5e-21 77.3 2.2 2.2 1 1 1 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CAR27488.1 - 8.9e-17 60.8 3.4 1.3e-08 34.6 0.1 2.9 3 0 0 3 3 3 2 Surp module CSD PF00313.22 CAR27488.1 - 0.024 14.5 0.1 1 9.3 0.1 2.5 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain SPATA48 PF15073.6 CAR27488.1 - 0.046 14.0 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 Sec10 PF07393.11 CAR27489.1 - 1e-68 232.5 24.6 1.3e-68 232.1 24.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 TFIIE_alpha PF02002.17 CAR27489.1 - 0.0075 16.1 0.3 0.042 13.7 0.3 2.4 1 0 0 1 1 1 1 TFIIE alpha subunit Spore_III_AB PF09548.10 CAR27489.1 - 1.1 9.3 6.5 2.5 8.2 3.4 2.7 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Fungal_trans PF04082.18 CAR27490.1 - 1.2e-34 119.5 2.4 1.8e-34 119.0 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR27490.1 - 3.4e-09 36.7 13.6 7.3e-09 35.6 13.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CAR27490.1 - 0.0023 16.8 1.6 0.004 16.0 1.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain HEAT PF02985.22 CAR27491.1 - 0.00023 21.2 0.2 1.8 9.0 0.0 4.1 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 CAR27491.1 - 0.0005 20.1 2.1 0.0032 17.5 0.0 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CAR27491.1 - 0.49 10.6 2.2 6.2 7.0 0.0 3.9 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3535 PF12054.8 CAR27491.1 - 1.3 8.2 6.4 0.21 10.8 1.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3535) Endonuclease_NS PF01223.23 CAR27492.1 - 5.5e-68 229.2 0.0 6.5e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease SPO22 PF08631.10 CAR27493.1 - 0.014 14.9 2.0 0.88 9.0 0.1 2.9 2 1 1 3 3 3 0 Meiosis protein SPO22/ZIP4 like MA3 PF02847.17 CAR27493.1 - 0.23 11.4 2.4 5.7 7.0 0.0 3.6 3 0 0 3 3 3 0 MA3 domain Pex2_Pex12 PF04757.14 CAR27494.1 - 1.9e-13 50.5 9.2 3.4e-13 49.7 9.2 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Zn_clus PF00172.18 CAR27495.1 - 7.6e-07 29.2 9.4 7.6e-07 29.2 9.4 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 CAR27496.1 - 2.1e-59 197.4 1.1 5.7e-21 74.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 CAR27496.1 - 0.0049 17.1 0.0 4.8 7.5 0.0 3.3 2 1 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF4813 PF16072.5 CAR27497.1 - 0.014 15.1 19.7 0.019 14.7 19.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Med3 PF11593.8 CAR27497.1 - 0.041 13.1 13.4 0.064 12.4 13.4 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Homeodomain PF00046.29 CAR27498.1 - 2.9e-10 39.8 0.6 7.6e-10 38.5 0.1 1.9 2 1 0 2 2 2 1 Homeodomain Cys_box PF17869.1 CAR27498.1 - 0.048 13.8 0.1 0.075 13.2 0.1 1.3 1 0 0 1 1 1 0 Anosmin cysteine rich domain DUF434 PF04256.12 CAR27498.1 - 0.079 12.7 1.3 11 5.8 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF434) ApbA_C PF08546.11 CAR27499.1 - 4.7e-30 104.4 0.0 8e-30 103.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CAR27499.1 - 2.3e-26 92.3 0.2 3e-26 91.9 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA CspB_prodomain PF18425.1 CAR27499.1 - 0.13 12.3 0.2 0.67 10.0 0.0 2.1 2 0 0 2 2 2 0 Csp protease B prodomain Fungal_trans_2 PF11951.8 CAR27500.1 - 1.4e-54 185.4 0.3 1.7e-54 185.2 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR27500.1 - 0.00019 21.5 10.1 0.00033 20.7 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_L-PSP PF01042.21 CAR27501.1 - 6.4e-24 84.3 0.0 7.8e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP RPN1_RPN2_N PF17781.1 CAR27501.1 - 0.04 13.3 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain NRho PF16733.5 CAR27501.1 - 0.15 12.1 0.0 0.46 10.6 0.0 1.7 2 0 0 2 2 2 0 Rhomboid N-terminal domain Flavodoxin_2 PF02525.17 CAR27502.1 - 5.2e-47 160.1 0.0 6.2e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CAR27502.1 - 1.5e-12 47.5 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Aminotran_3 PF00202.21 CAR27503.1 - 9.8e-62 208.9 0.0 1.1e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III CarS-like PF01864.17 CAR27503.1 - 0.37 10.8 1.4 0.55 10.2 0.2 1.8 2 0 0 2 2 2 0 CDP-archaeol synthase AA_permease PF00324.21 CAR27504.1 - 1.2e-110 370.3 39.4 1.5e-110 370.0 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR27504.1 - 1.3e-25 90.1 44.8 2.1e-25 89.5 44.3 1.4 1 1 0 1 1 1 1 Amino acid permease TMEM239 PF15841.5 CAR27504.1 - 0.061 13.2 2.6 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 Transmembrane protein 239 family FMN_dh PF01070.18 CAR27505.1 - 5.6e-93 311.7 0.0 1.2e-92 310.7 0.0 1.5 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CAR27505.1 - 3.7e-20 71.9 0.0 1.1e-19 70.3 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CAR27505.1 - 1.3e-07 31.1 0.1 2.9e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CAR27505.1 - 1.2e-05 24.5 0.3 0.00026 20.1 0.1 2.2 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CAR27505.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 CAR27505.1 - 0.04 13.4 0.3 1.9 7.9 0.0 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein Glu_syn_central PF04898.14 CAR27505.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Glutamate synthase central domain Epimerase PF01370.21 CAR27506.1 - 8.9e-22 77.7 0.0 1.6e-21 76.9 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CAR27506.1 - 8.3e-14 51.4 0.0 5.1e-08 32.4 0.0 2.5 2 1 1 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 CAR27506.1 - 1.3e-13 50.6 0.0 1.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CAR27506.1 - 1.3e-12 47.7 0.0 2.4e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CAR27506.1 - 3.5e-09 36.8 0.0 5.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CAR27506.1 - 3.2e-07 29.8 0.0 1.6e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 CAR27506.1 - 5.1e-07 29.3 0.0 1.3e-05 24.8 0.0 2.5 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 CAR27506.1 - 0.00023 20.8 0.0 0.0014 18.2 0.1 2.1 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 CAR27506.1 - 0.002 18.1 0.0 0.0047 16.9 0.0 1.6 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CAR27506.1 - 0.0066 15.6 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain OPT PF03169.15 CAR27507.1 - 2.4e-114 383.2 41.5 2.8e-114 383.0 41.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein SHR3_chaperone PF08229.11 CAR27507.1 - 0.058 12.4 0.3 0.15 11.0 0.3 1.7 1 0 0 1 1 1 0 ER membrane protein SH3 COX7a PF02238.15 CAR27507.1 - 0.33 11.4 9.0 4.7 7.7 0.6 4.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII TMEM208_SND2 PF05620.11 CAR27507.1 - 6.6 6.5 12.0 4.1 7.2 1.5 3.8 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 DUP PF00674.18 CAR27508.1 - 3.9e-30 104.0 3.7 1.1e-15 57.6 0.2 2.3 2 0 0 2 2 2 2 DUP family AbiJ_NTD3 PF18860.1 CAR27508.1 - 0.05 13.1 0.1 1.5 8.4 0.0 2.7 2 1 1 3 3 3 0 AbiJ N-terminal domain 3 Sortilin-Vps10 PF15902.5 CAR27509.1 - 2.1e-51 175.2 0.0 8.1e-25 87.5 0.0 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CAR27509.1 - 5.5e-15 56.1 0.4 1.2e-14 55.0 0.4 1.5 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CAR27509.1 - 2.5e-09 35.7 19.6 0.35 11.1 0.3 8.2 8 0 0 8 8 8 5 BNR/Asp-box repeat PSII_BNR PF14870.6 CAR27509.1 - 0.0046 16.2 0.2 0.057 12.7 0.0 2.6 3 1 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 DUP PF00674.18 CAR27510.1 - 1.5e-34 118.2 1.0 9e-18 64.3 0.4 2.4 2 1 0 2 2 2 2 DUP family Phage_tail_X PF05489.12 CAR27510.1 - 0.089 12.5 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Phage Tail Protein X DUP PF00674.18 CAR27511.1 - 2e-07 31.1 0.9 2e-07 31.1 0.9 2.2 2 0 0 2 2 2 1 DUP family DUP PF00674.18 CAR27512.1 - 1.2e-09 38.2 0.2 1.2e-09 38.2 0.2 2.8 2 1 1 3 3 3 1 DUP family DUP PF00674.18 CAR27513.1 - 1.5e-32 111.8 4.9 1.3e-16 60.6 0.0 2.6 2 1 0 2 2 2 2 DUP family DUF1360 PF07098.11 CAR27513.1 - 0.012 15.6 0.2 0.012 15.6 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) Erf4 PF10256.9 CAR27513.1 - 0.13 12.4 0.6 16 5.6 0.1 2.7 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family DUP PF00674.18 CAR27514.1 - 2.4e-09 37.2 0.2 2.4e-09 37.2 0.2 2.4 2 0 0 2 2 2 1 DUP family MFS_1 PF07690.16 CAR27515.1 - 9.8e-33 113.5 42.9 9.8e-33 113.5 42.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR27515.1 - 5.9e-13 48.5 13.4 5.9e-13 48.5 13.4 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter OPT PF03169.15 CAR27516.1 - 3.7e-157 524.6 44.3 4.5e-157 524.4 44.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUP PF00674.18 CAR27517.1 - 4.6e-32 110.2 1.0 3.4e-17 62.5 0.1 2.7 2 1 1 3 3 3 2 DUP family DHO_dh PF01180.21 CAR27518.1 - 1.1e-90 303.8 0.0 1.3e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CAR27518.1 - 9.7e-06 24.8 0.0 8.7e-05 21.7 0.0 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Polysacc_deac_1 PF01522.21 CAR27518.1 - 0.00022 21.1 0.0 0.00083 19.2 0.0 2.0 3 0 0 3 3 3 1 Polysaccharide deacetylase DUF885 PF05960.11 CAR27518.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) GST_N PF02798.20 CAR27519.1 - 6.2e-17 61.7 0.0 1.2e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CAR27519.1 - 5.4e-09 36.2 0.0 1.4e-08 34.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CAR27519.1 - 7.5e-09 35.9 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CAR27519.1 - 7e-07 29.5 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CAR27519.1 - 9.5e-05 22.5 0.0 0.00044 20.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAR27519.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Aminotran_5 PF00266.19 CAR27520.1 - 2.9e-16 59.4 0.0 3.9e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CAR27520.1 - 0.00094 18.4 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CAR27520.1 - 0.0072 15.7 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CAR27520.1 - 0.012 14.4 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Glutaredoxin PF00462.24 CAR27520.1 - 0.066 13.5 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 Glutaredoxin DUF2805 PF10985.8 CAR27520.1 - 0.1 13.0 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) Pan3_PK PF18101.1 CAR27522.1 - 2.9e-52 176.3 0.2 4.5e-52 175.7 0.2 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CAR27522.1 - 0.0031 16.9 0.0 0.0055 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain CCDC84 PF14968.6 CAR27522.1 - 0.23 11.0 0.8 5.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Coiled coil protein 84 adh_short PF00106.25 CAR27523.1 - 8e-47 159.2 0.9 9.8e-47 158.9 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR27523.1 - 3.4e-32 111.9 0.1 3.8e-32 111.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR27523.1 - 7.1e-13 48.8 0.4 9.6e-13 48.4 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CAR27523.1 - 8.9e-06 25.3 0.1 3.9e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CAR27523.1 - 0.00014 21.1 0.2 0.00019 20.7 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CAR27523.1 - 0.002 17.3 0.1 0.017 14.3 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CAR27523.1 - 0.0022 17.9 0.1 0.0033 17.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 CAR27523.1 - 0.0038 17.5 0.2 0.006 16.8 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain partial_CstF PF15861.5 CAR27523.1 - 0.039 13.7 0.3 11 5.9 0.2 3.0 2 1 0 2 2 2 0 Partial cleavage stimulation factor domain DapB_N PF01113.20 CAR27523.1 - 0.069 13.3 0.7 0.76 9.9 0.6 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 CAR27523.1 - 0.086 12.2 0.2 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ADK PF00406.22 CAR27524.1 - 4.3e-46 156.8 0.1 5.6e-46 156.4 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CAR27524.1 - 1.5e-35 122.6 0.1 2.1e-35 122.1 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAR27524.1 - 8.5e-09 36.0 0.0 1.6e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAR27524.1 - 1.1e-07 32.1 0.0 3.2e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CAR27524.1 - 0.00045 19.9 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 CAR27524.1 - 0.0035 17.0 0.6 1.4 8.5 0.1 2.3 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.12 CAR27524.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin Ploopntkinase3 PF18751.1 CAR27524.1 - 0.058 13.3 0.0 0.16 11.8 0.0 1.7 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 APC_r PF05923.12 CAR27524.1 - 0.49 10.2 2.1 0.93 9.3 1.0 2.1 2 0 0 2 2 2 0 APC repeat TPR_1 PF00515.28 CAR27526.1 - 6.3e-35 117.6 4.9 1.4e-05 24.7 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 CAR27526.1 - 2.5e-32 108.4 7.6 0.0011 18.9 0.0 9.8 10 0 0 10 10 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR27526.1 - 1.8e-26 92.2 18.9 8.3e-23 80.4 0.0 5.6 4 2 4 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CAR27526.1 - 8.3e-26 88.0 11.5 0.00015 21.7 0.0 8.9 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 CAR27526.1 - 6.9e-19 67.9 14.1 2.9e-09 37.1 0.1 8.4 6 2 3 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 CAR27526.1 - 8.1e-16 57.4 6.9 9.3e-07 28.4 0.0 7.3 5 2 2 7 7 7 3 TPR repeat TPR_14 PF13428.6 CAR27526.1 - 1.5e-15 56.5 4.7 0.064 14.1 0.0 8.6 5 2 4 9 9 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CAR27526.1 - 1.7e-15 57.3 0.0 0.00022 21.8 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR27526.1 - 1.3e-14 53.4 2.9 0.0071 16.6 0.0 7.5 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 CAR27526.1 - 1.2e-13 51.3 9.7 0.0028 18.1 0.0 6.9 4 2 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 CAR27526.1 - 1.5e-12 46.6 12.0 0.00011 22.0 0.0 7.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 CAR27526.1 - 2.6e-11 43.0 1.5 0.013 15.3 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAR27526.1 - 4e-09 36.5 0.1 0.001 19.2 0.0 3.6 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CAR27526.1 - 1.3e-07 31.1 0.8 0.0047 16.2 0.2 3.5 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAR27526.1 - 4.6e-07 30.1 7.1 1.2 9.9 0.0 7.1 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CAR27526.1 - 5.1e-07 29.4 0.1 0.00052 19.5 0.0 3.4 3 1 1 4 4 4 2 MalT-like TPR region Fis1_TPR_C PF14853.6 CAR27526.1 - 0.00033 20.7 9.2 4.5 7.4 0.3 5.3 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_5 PF12688.7 CAR27526.1 - 0.0034 17.6 0.2 3.7 7.8 0.0 2.8 2 0 0 2 2 2 2 Tetratrico peptide repeat TPR_4 PF07721.14 CAR27526.1 - 0.015 15.9 0.3 4.6 8.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CAR27526.1 - 0.48 10.5 7.9 2.6 8.1 0.3 3.9 4 1 1 5 5 5 0 Putative TPR-like repeat TPR_21 PF09976.9 CAR27526.1 - 1.8 8.2 6.9 5.1 6.8 0.3 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat-like domain AlaDh_PNT_N PF05222.15 CAR27527.1 - 2.4e-30 105.6 0.0 3.4e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 CAR27527.1 - 0.061 12.6 0.0 0.28 10.4 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain WD40 PF00400.32 CAR27528.1 - 6.9e-21 74.2 6.3 3.8e-06 27.5 0.3 5.5 4 1 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27528.1 - 2.2e-05 24.6 1.4 1.5 9.1 0.0 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR27528.1 - 0.00025 19.8 0.0 0.062 11.9 0.0 2.5 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CAR27528.1 - 0.0044 16.0 0.1 0.26 10.2 0.0 2.9 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Nucleoporin_N PF08801.11 CAR27528.1 - 0.007 15.2 1.5 10 4.7 0.1 3.6 2 1 2 4 4 4 2 Nup133 N terminal like CRT10 PF08728.10 CAR27528.1 - 0.02 13.1 0.0 0.026 12.7 0.0 1.3 1 0 0 1 1 1 0 CRT10 FliO PF04347.13 CAR27528.1 - 0.039 14.2 0.0 0.28 11.5 0.0 2.3 2 0 0 2 2 2 0 Flagellar biosynthesis protein, FliO TIG PF01833.24 CAR27529.1 - 1.6e-08 34.5 6.3 3.1e-08 33.6 1.9 2.7 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 CAR27529.1 - 1.9e-08 34.8 0.0 7.2e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAR27529.1 - 4.7e-08 33.4 0.0 2.4e-07 31.2 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAR27529.1 - 2.7e-07 30.3 0.0 0.004 17.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CAR27529.1 - 5.6e-07 29.7 0.1 0.00045 20.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CAR27529.1 - 1.4e-05 25.2 0.0 0.00041 20.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RHD_dimer PF16179.5 CAR27529.1 - 0.0018 18.2 0.0 0.0047 16.9 0.0 1.7 1 0 0 1 1 1 1 Rel homology dimerisation domain PPTA PF01239.22 CAR27530.1 - 2.7e-36 122.2 10.7 2.5e-08 33.4 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat ACPS PF01648.20 CAR27530.1 - 0.022 14.9 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily DSPc PF00782.20 CAR27531.1 - 4.5e-25 88.0 0.3 7.8e-24 84.0 0.3 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR27531.1 - 0.035 13.7 0.0 0.085 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF357 PF04010.13 CAR27531.1 - 0.088 12.9 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF357) DUF2812 PF11193.8 CAR27531.1 - 0.096 12.9 0.4 0.22 11.7 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2812) Zn_ribbon_SprT PF17283.2 CAR27531.1 - 0.73 9.8 0.1 0.73 9.8 0.1 3.0 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Apc15p PF05841.11 CAR27532.1 - 3.6e-40 137.6 9.5 3.6e-40 137.6 9.5 2.6 2 1 1 3 3 3 1 Apc15p protein DUF3578 PF12102.8 CAR27532.1 - 0.56 9.8 4.4 0.7 9.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3578) DUF1748 PF08520.10 CAR27533.1 - 1.3e-19 69.9 0.2 1.7e-19 69.5 0.2 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DUF3007 PF11460.8 CAR27533.1 - 0.054 13.8 0.1 0.069 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) WD40 PF00400.32 CAR27534.1 - 2.1e-11 44.1 0.1 0.00032 21.5 0.0 5.2 5 1 1 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27534.1 - 1.6e-05 25.1 0.0 1.1 9.6 0.0 3.5 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 CAR27534.1 - 0.098 11.9 0.0 0.34 10.1 0.0 1.8 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller AAA_12 PF13087.6 CAR27535.1 - 1.1e-58 198.1 0.0 2.6e-58 196.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAR27535.1 - 3.2e-54 184.5 0.1 6.6e-54 183.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR27535.1 - 1.1e-12 48.5 0.0 3.2e-12 47.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR27535.1 - 3.2e-12 46.6 0.0 1.4e-10 41.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CAR27535.1 - 4.9e-08 33.0 0.4 0.095 12.4 0.0 3.5 4 0 0 4 4 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CAR27535.1 - 1.5e-06 28.0 0.0 0.00034 20.2 0.0 2.0 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 CAR27535.1 - 1.3e-05 25.2 0.0 0.00011 22.2 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAR27535.1 - 7.5e-05 23.0 0.1 0.00037 20.8 0.1 2.3 2 1 0 2 2 1 1 AAA domain Helicase_RecD PF05127.14 CAR27535.1 - 0.00011 22.1 0.0 0.00055 19.8 0.0 2.2 3 0 0 3 3 2 1 Helicase DEAD PF00270.29 CAR27535.1 - 0.0002 21.2 0.1 0.0013 18.6 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase TrwB_AAD_bind PF10412.9 CAR27535.1 - 0.0027 16.7 0.0 0.0054 15.7 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.14 CAR27535.1 - 0.0028 16.9 0.0 0.18 11.0 0.0 2.4 2 0 0 2 2 2 1 PIF1-like helicase PhoH PF02562.16 CAR27535.1 - 0.0037 16.7 0.0 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.6 CAR27535.1 - 0.0038 17.6 0.0 0.0085 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CAR27535.1 - 0.0062 17.0 0.8 0.026 15.0 0.2 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CAR27535.1 - 0.0067 16.2 0.1 0.049 13.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CAR27535.1 - 0.0078 16.0 0.0 0.027 14.2 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein Rad17 PF03215.15 CAR27535.1 - 0.0087 16.0 0.1 3.7 7.4 0.0 2.8 1 1 1 2 2 2 1 Rad17 P-loop domain Flavi_DEAD PF07652.14 CAR27535.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF2075 PF09848.9 CAR27535.1 - 0.011 15.0 0.0 0.03 13.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 CAR27535.1 - 0.017 15.2 0.0 0.056 13.5 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF853 PF05872.12 CAR27535.1 - 0.021 13.4 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_14 PF13173.6 CAR27535.1 - 0.027 14.5 0.1 0.67 10.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain GTP_EFTU_D2 PF03144.25 CAR27535.1 - 0.05 14.0 0.5 4.4 7.8 0.1 2.9 2 0 0 2 2 2 0 Elongation factor Tu domain 2 AAA_18 PF13238.6 CAR27535.1 - 0.067 13.7 0.2 5.2 7.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 CAR27535.1 - 0.069 13.0 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 CAR27535.1 - 0.084 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Zot PF05707.12 CAR27535.1 - 0.085 12.5 0.0 0.27 10.9 0.0 1.9 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) MeaB PF03308.16 CAR27535.1 - 0.087 11.8 0.0 0.22 10.4 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CAR27535.1 - 0.096 12.8 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR27535.1 - 0.12 12.2 0.1 0.68 9.8 0.0 2.3 2 1 0 2 2 1 0 NACHT domain Fer4_NifH PF00142.18 CAR27535.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNA_pol_Rpc82 PF05645.13 CAR27536.1 - 1.4e-62 211.8 0.1 3.7e-62 210.4 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 CAR27536.1 - 3.6e-23 81.4 1.7 6.8e-17 61.3 0.2 3.5 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 CAR27536.1 - 2.7e-05 24.0 0.3 0.28 11.1 0.1 2.9 3 0 0 3 3 3 2 TFIIE alpha subunit Spindle_Spc25 PF08234.12 CAR27536.1 - 0.1 12.8 0.3 1.3 9.3 0.2 2.4 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 TPR_22 PF18833.1 CAR27537.1 - 6.2e-41 138.4 1.8 1.1e-40 137.6 0.6 2.2 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR27537.1 - 5.7e-29 100.4 8.0 5e-06 26.9 0.1 10.4 11 2 1 12 12 10 5 Tetratricopeptide repeat TPR_2 PF07719.17 CAR27537.1 - 2.7e-27 92.7 17.0 7.3e-06 25.7 0.0 14.7 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_16 PF13432.6 CAR27537.1 - 2.7e-21 75.9 0.0 0.0001 22.9 0.0 9.2 7 2 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 CAR27537.1 - 2.2e-20 71.6 4.2 0.0027 18.4 0.0 12.6 7 5 6 13 13 12 4 Tetratricopeptide repeat TPR_1 PF00515.28 CAR27537.1 - 5.2e-20 70.4 21.0 3.8e-06 26.5 0.0 13.4 16 0 0 16 16 15 3 Tetratricopeptide repeat TPR_12 PF13424.6 CAR27537.1 - 6.9e-17 61.5 13.8 0.00031 21.0 0.2 10.2 11 1 1 12 12 10 4 Tetratricopeptide repeat TPR_11 PF13414.6 CAR27537.1 - 8.6e-16 57.4 5.3 0.0001 21.9 0.1 8.2 7 1 2 9 9 9 4 TPR repeat ANAPC3 PF12895.7 CAR27537.1 - 9.9e-14 51.3 14.1 2.3e-05 24.5 0.2 6.8 6 0 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CAR27537.1 - 3e-13 48.9 30.1 3.2e-06 26.9 0.0 14.4 17 1 1 18 18 15 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAR27537.1 - 3.5e-11 42.7 5.5 0.3 11.5 0.0 8.9 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAR27537.1 - 6.9e-11 42.1 5.9 1.7 9.4 0.1 9.8 10 1 0 10 10 8 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CAR27537.1 - 7e-07 29.8 3.9 0.031 14.7 0.1 4.8 4 0 0 4 4 4 2 Alkyl sulfatase dimerisation TPR_9 PF13371.6 CAR27537.1 - 1.6e-06 28.2 0.9 0.22 11.7 0.0 4.6 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CAR27537.1 - 4.4e-06 26.3 6.9 0.0072 15.7 0.0 4.6 4 1 1 5 5 5 2 MalT-like TPR region TPR_7 PF13176.6 CAR27537.1 - 8.7e-06 25.4 4.3 0.81 9.9 0.0 7.8 9 0 0 9 9 7 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CAR27537.1 - 8.7e-05 22.2 1.0 0.11 12.2 0.0 5.1 5 1 1 6 6 6 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 CAR27537.1 - 0.0015 18.3 7.8 5.5 7.0 0.0 6.3 7 0 0 7 7 5 1 Tetratricopeptide repeat SieB PF14163.6 CAR27537.1 - 0.0087 15.6 0.3 0.027 14.0 0.3 1.8 1 0 0 1 1 1 1 Super-infection exclusion protein B TPR_20 PF14561.6 CAR27537.1 - 0.009 16.3 10.7 9.9 6.6 0.0 6.6 8 1 1 9 9 5 0 Tetratricopeptide repeat ChAPs PF09295.10 CAR27537.1 - 0.02 13.9 12.3 0.25 10.3 0.1 5.2 6 0 0 6 6 6 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.14 CAR27537.1 - 0.028 15.0 4.3 98 4.0 0.1 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR27537.1 - 0.039 14.0 1.4 2.9 8.0 0.0 4.5 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat DUF348 PF03990.14 CAR27537.1 - 0.039 13.7 0.1 0.091 12.5 0.1 1.6 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain MIT PF04212.18 CAR27537.1 - 0.5 10.5 5.2 45 4.2 0.0 5.0 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain EF-hand_7 PF13499.6 CAR27538.1 - 2.3e-11 44.0 0.4 1.2e-08 35.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CAR27538.1 - 2.3e-06 27.3 1.6 0.0019 18.0 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CAR27538.1 - 3e-05 23.6 0.9 3e-05 23.6 0.9 3.4 4 1 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 CAR27538.1 - 3e-05 23.2 5.1 0.00013 21.3 1.0 3.2 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 CAR27538.1 - 0.00072 18.9 2.8 0.00072 18.9 2.8 1.9 2 0 0 2 2 2 1 EF hand DUF1456 PF07308.13 CAR27538.1 - 0.016 15.5 0.2 0.26 11.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) EF-hand_9 PF14658.6 CAR27538.1 - 0.027 14.8 0.0 6.4 7.2 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain DUF5071 PF16804.5 CAR27538.1 - 0.032 14.5 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) IF2_N PF04760.15 CAR27538.1 - 0.066 13.0 0.4 0.28 11.1 0.0 2.2 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region RNA_pol_Rpb6 PF01192.22 CAR27539.1 - 3.8e-17 61.9 0.1 5.5e-17 61.4 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.26 CAR27540.1 - 2.1e-25 87.7 59.3 0.00074 19.8 0.2 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR27540.1 - 1.7e-21 75.0 60.4 0.014 16.2 2.2 9.3 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR27540.1 - 2e-09 37.4 67.5 2.9e-05 24.3 0.8 9.9 10 1 0 10 10 10 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CAR27540.1 - 2.9e-08 33.8 36.0 0.065 13.5 0.4 8.7 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CAR27540.1 - 1.2e-05 25.5 26.4 0.00061 20.0 1.5 4.8 2 1 3 5 5 5 2 C2H2-type zinc ribbon zf-met PF12874.7 CAR27540.1 - 0.00025 21.3 33.8 0.11 12.9 0.3 8.5 9 0 0 9 9 9 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CAR27540.1 - 0.055 13.2 0.2 0.055 13.2 0.2 4.0 4 0 0 4 4 4 0 zinc-finger C2H2-type zf_UBZ PF18439.1 CAR27540.1 - 1 9.0 18.8 5.1 6.8 0.0 5.7 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger FOXP-CC PF16159.5 CAR27540.1 - 1.5 9.5 30.8 0.43 11.3 0.2 7.1 5 2 3 8 8 8 0 FOXP coiled-coil domain IBR PF01485.21 CAR27540.1 - 5.5 7.3 31.3 0.34 11.2 2.2 5.1 3 1 1 4 4 4 0 IBR domain, a half RING-finger domain ATG13 PF10033.9 CAR27541.1 - 6.6e-66 222.4 0.1 1.1e-65 221.7 0.1 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 hDGE_amylase PF14701.6 CAR27542.1 - 3.9e-167 556.8 0.0 6.7e-167 556.0 0.0 1.4 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CAR27542.1 - 3e-128 428.0 0.0 4.1e-128 427.5 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CAR27542.1 - 1.9e-75 253.8 0.0 6.9e-75 252.0 0.0 1.9 2 0 0 2 2 2 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CAR27542.1 - 7.5e-23 80.5 0.0 1.9e-22 79.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 CAR27542.1 - 1.2e-06 28.4 0.1 3.6e-05 23.5 0.4 2.3 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Peptidase_M91 PF14891.6 CAR27542.1 - 0.11 12.9 0.0 7.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Effector protein Glycos_transf_2 PF00535.26 CAR27543.1 - 5.1e-31 107.8 0.0 6.9e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CAR27543.1 - 3.1e-07 30.5 0.0 4.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CAR27543.1 - 0.025 14.0 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 LSM PF01423.22 CAR27544.1 - 3.6e-18 65.0 0.2 4.2e-18 64.8 0.2 1.1 1 0 0 1 1 1 1 LSM domain PIG-U PF06728.13 CAR27545.1 - 1.1e-101 340.7 36.2 1.3e-101 340.5 36.2 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Sec23_trunk PF04811.15 CAR27546.1 - 2.8e-75 253.0 0.0 4e-75 252.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CAR27546.1 - 7e-29 100.4 0.1 1.5e-28 99.3 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CAR27546.1 - 4.8e-27 93.8 0.0 1.1e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CAR27546.1 - 2.7e-12 46.5 7.6 5e-12 45.7 7.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CAR27546.1 - 8.9e-11 41.5 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CAR27546.1 - 0.00074 18.9 1.6 0.0018 17.6 1.6 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 CAR27546.1 - 0.014 16.0 0.0 12 6.6 0.0 2.7 1 1 1 2 2 2 0 von Willebrand factor type A domain zf-MIZ PF02891.20 CAR27546.1 - 0.036 13.8 1.8 0.077 12.8 1.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zinc_ribbon_10 PF10058.9 CAR27546.1 - 0.34 10.7 2.0 2.5 7.9 2.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein ThiF PF00899.21 CAR27547.1 - 2.4e-34 118.8 0.0 3.2e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CAR27547.1 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CAR27547.1 - 0.064 13.7 0.0 0.21 12.1 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding HDA2-3 PF11496.8 CAR27548.1 - 3.7e-90 302.1 0.6 3.7e-90 302.1 0.6 2.0 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERM PF00769.19 CAR27548.1 - 0.0021 17.9 23.1 0.0021 17.9 23.1 1.9 1 1 0 1 1 1 1 Ezrin/radixin/moesin family DUF948 PF06103.11 CAR27548.1 - 0.19 12.0 1.3 1 9.7 1.3 2.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF236 PF03057.14 CAR27548.1 - 0.22 11.5 0.2 0.44 10.5 0.2 1.4 1 0 0 1 1 1 0 DUF236 repeat CENP-Q PF13094.6 CAR27548.1 - 1.4 9.1 19.5 1.1 9.5 17.7 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit WD40 PF00400.32 CAR27549.1 - 1.4e-42 142.8 9.5 3.6e-10 40.3 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27549.1 - 3.2e-20 72.2 0.1 9.3e-06 25.9 0.0 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR27549.1 - 7.9e-05 21.8 0.0 3.8 6.4 0.0 3.8 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CAR27549.1 - 0.0017 17.7 0.0 0.22 10.8 0.0 3.3 3 1 0 3 3 3 1 WD40-like domain Nbas_N PF15492.6 CAR27549.1 - 0.0098 15.3 0.1 0.11 11.8 0.0 2.4 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 CAR27549.1 - 0.013 14.0 0.0 0.045 12.3 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain PRP4 PF08799.11 CAR27549.1 - 0.022 14.3 0.1 0.045 13.3 0.1 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Prenyltrans PF00432.21 CAR27550.1 - 1.6e-62 206.9 4.9 1.7e-13 50.0 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CAR27550.1 - 3e-06 26.6 0.0 0.00015 21.0 0.0 2.2 1 1 1 2 2 2 1 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 CAR27550.1 - 0.0031 16.6 0.0 0.071 12.1 0.0 2.8 2 1 1 3 3 3 1 A-macroglobulin TED domain SQHop_cyclase_N PF13249.6 CAR27550.1 - 0.014 14.5 0.0 11 5.1 0.0 3.5 1 1 3 4 4 4 0 Squalene-hopene cyclase N-terminal domain DUF5354 PF17305.2 CAR27550.1 - 0.022 15.0 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5354) DUF4576 PF15144.6 CAR27550.1 - 0.043 13.7 0.0 15 5.6 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4576) DNA_pol_E_B PF04042.16 CAR27551.1 - 1.7e-56 190.9 1.4 2.7e-56 190.2 1.4 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF4047 PF13256.6 CAR27551.1 - 0.0028 17.8 0.8 0.0028 17.8 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4047) NBP1 PF08537.10 CAR27552.1 - 3.3e-131 437.7 11.1 3.7e-131 437.6 11.1 1.0 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 ING PF12998.7 CAR27552.1 - 0.024 15.2 1.8 0.055 14.1 0.2 2.4 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding AAA PF00004.29 CAR27553.1 - 3.8e-43 147.1 0.0 6.3e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CAR27553.1 - 4.7e-28 97.0 0.0 1.8e-27 95.1 0.1 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CAR27553.1 - 1e-22 79.9 3.5 1e-22 79.9 3.5 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_16 PF13191.6 CAR27553.1 - 4.7e-06 27.1 0.3 0.00015 22.2 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_lid_3 PF17862.1 CAR27553.1 - 6.1e-06 25.9 0.0 2.3e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CAR27553.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CAR27553.1 - 1.6e-05 24.9 0.0 8.2e-05 22.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAR27553.1 - 2.7e-05 24.4 0.1 0.003 17.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 CAR27553.1 - 3.1e-05 23.3 0.0 0.00012 21.3 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CAR27553.1 - 6.3e-05 22.8 0.0 0.00019 21.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.6 CAR27553.1 - 0.00025 21.1 0.0 0.00081 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CAR27553.1 - 0.00027 20.3 0.0 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 CAR27553.1 - 0.00028 21.3 0.0 0.0089 16.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 CAR27553.1 - 0.00059 20.4 0.1 0.0016 19.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 CAR27553.1 - 0.00078 19.6 0.1 0.0023 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 CAR27553.1 - 0.0022 17.7 0.2 0.0087 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR27553.1 - 0.0024 18.1 0.0 0.0066 16.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 CAR27553.1 - 0.0032 17.1 0.1 0.26 10.8 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 CAR27553.1 - 0.008 16.6 0.1 0.031 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CAR27553.1 - 0.027 14.0 0.0 0.071 12.6 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CAR27553.1 - 0.031 13.6 0.4 1.1 8.5 0.0 3.0 1 1 2 3 3 3 0 Zeta toxin ATPase PF06745.13 CAR27553.1 - 0.035 13.5 0.3 4.6 6.5 0.0 2.7 1 1 2 3 3 3 0 KaiC Mg_chelatase PF01078.21 CAR27553.1 - 0.035 13.5 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.11 CAR27553.1 - 0.044 13.9 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 Torsin PhoH PF02562.16 CAR27553.1 - 0.071 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Use1 PF09753.9 CAR27553.1 - 0.072 12.8 1.6 0.13 12.0 1.6 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 NACHT PF05729.12 CAR27553.1 - 0.078 12.9 0.0 0.68 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 CAR27553.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 CAR27553.1 - 0.11 12.2 0.0 0.35 10.6 0.0 1.8 1 1 1 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 CAR27553.1 - 0.32 10.9 2.3 2.3 8.1 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Putative_PNPOx PF01243.20 CAR27554.1 - 5.7e-17 61.7 0.0 3e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 CAR27554.1 - 0.0048 16.5 0.1 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase like RecQ5 PF06959.11 CAR27554.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) PWWP PF00855.17 CAR27555.1 - 6.4e-17 61.7 0.1 6.4e-17 61.7 0.1 2.4 3 1 0 3 3 3 1 PWWP domain TFB6 PF17110.5 CAR27555.1 - 5.3 6.7 9.0 0.34 10.6 3.8 1.7 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH BRCA2 PF00634.18 CAR27556.1 - 0.062 13.0 1.7 0.26 11.0 0.4 2.5 2 0 0 2 2 2 0 BRCA2 repeat ANAPC4_WD40 PF12894.7 CAR27558.1 - 0.0029 17.9 0.1 0.045 14.1 0.1 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CAR27558.1 - 0.027 15.0 0.3 2.4 8.7 0.0 3.9 5 0 0 5 5 5 0 PQQ-like domain EFG_II PF14492.6 CAR27558.1 - 0.084 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Elongation Factor G, domain II WD40 PF00400.32 CAR27558.1 - 0.094 13.6 0.3 4.9 8.2 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Med10 PF09748.9 CAR27559.1 - 1.7e-38 131.3 0.8 2e-38 131.1 0.8 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Herpes_UL25 PF01499.16 CAR27559.1 - 0.041 12.4 0.1 0.063 11.8 0.0 1.4 1 1 1 2 2 2 0 Herpesvirus UL25 family PIN_5 PF08745.11 CAR27559.1 - 0.084 12.3 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 PINc domain ribonuclease MogR_DNAbind PF12181.8 CAR27559.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) NPV_P10 PF05531.12 CAR27559.1 - 0.34 11.4 3.3 1.7 9.1 0.1 2.8 2 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein PAPS_reduct PF01507.19 CAR27560.1 - 2.5e-38 131.8 0.0 3.1e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF4727 PF15856.5 CAR27560.1 - 0.01 15.4 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) MBD PF01429.19 CAR27560.1 - 0.15 11.8 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Methyl-CpG binding domain Ribosomal_S14 PF00253.21 CAR27561.1 - 1.8e-20 72.4 0.6 3.2e-20 71.6 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ras PF00071.22 CAR27562.1 - 3.3e-54 182.8 0.0 4.8e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR27562.1 - 2.6e-21 76.1 0.0 7.7e-21 74.5 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR27562.1 - 5e-07 29.3 0.0 1.2e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAR27562.1 - 0.00017 21.2 0.1 0.00061 19.4 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ETRAMP PF09716.10 CAR27562.1 - 0.0087 16.1 0.1 0.011 15.8 0.1 1.3 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) Ras PF00071.22 CAR27563.1 - 3.8e-55 185.9 0.0 4.5e-55 185.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR27563.1 - 3.4e-21 75.7 0.0 5.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR27563.1 - 5.5e-07 29.2 0.0 7.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR27563.1 - 0.087 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CAR27563.1 - 0.096 12.1 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NLBH PF05211.12 CAR27564.1 - 0.04 13.5 0.1 0.085 12.4 0.1 1.4 1 0 0 1 1 1 0 Neuraminyllactose-binding hemagglutinin precursor (NLBH) Mpp10 PF04006.12 CAR27564.1 - 1.3 7.4 15.0 2 6.8 15.0 1.1 1 0 0 1 1 1 0 Mpp10 protein Voldacs PF03517.13 CAR27564.1 - 9.9 6.3 9.2 31 4.7 9.2 1.9 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Fmp27 PF10344.9 CAR27565.1 - 1.2e-112 377.7 20.3 2.7e-112 376.6 20.3 1.6 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.9 CAR27565.1 - 4e-105 352.5 5.2 9.2e-105 351.3 5.2 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 CAR27565.1 - 1.1e-63 215.8 7.6 2.4e-45 155.3 0.1 2.7 2 1 1 3 3 3 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 CAR27565.1 - 1.7e-54 184.1 0.0 3e-53 180.1 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CAR27565.1 - 7.1e-54 181.9 2.2 2.4e-53 180.2 1.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CAR27565.1 - 4e-32 111.0 1.9 1.1e-31 109.5 0.1 2.8 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain Get5_bdg PF16843.5 CAR27565.1 - 0.22 11.0 0.7 1 8.9 0.0 2.5 3 0 0 3 3 3 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein ORC4_C PF14629.6 CAR27567.1 - 5e-39 133.9 1.0 8.8e-39 133.1 1.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 CAR27567.1 - 2.5e-07 31.3 0.1 5.5e-07 30.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR27567.1 - 1.6e-06 28.5 0.1 3.7e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CAR27567.1 - 0.0025 16.9 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.12 CAR27567.1 - 0.0028 17.6 0.0 0.0071 16.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA PF00004.29 CAR27567.1 - 0.0035 17.8 0.1 0.039 14.4 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CAR27567.1 - 0.01 15.3 0.0 0.03 13.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region Pkinase PF00069.25 CAR27568.1 - 4.5e-71 239.3 0.0 5.9e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27568.1 - 2.3e-27 95.9 0.0 2.6e-26 92.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR27568.1 - 2.2e-06 26.9 0.0 3.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CAR27568.1 - 0.014 14.5 0.3 0.022 13.8 0.3 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RGS PF00615.19 CAR27569.1 - 7.1e-18 65.0 0.0 2.8e-16 59.9 0.0 2.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 CAR27569.1 - 9.9e-10 38.3 0.0 1e-08 35.1 0.0 2.6 2 1 1 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) eIF2_C PF09173.11 CAR27570.1 - 9.8e-34 115.5 0.3 2.4e-33 114.2 0.3 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CAR27570.1 - 4.3e-23 81.9 0.3 4.2e-22 78.6 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CAR27570.1 - 9.1e-12 45.2 0.5 2.6e-11 43.7 0.5 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAR27570.1 - 0.0036 17.4 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR27570.1 - 0.007 16.3 0.0 0.094 12.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CAR27570.1 - 0.063 13.3 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain MGAT2 PF05060.14 CAR27570.1 - 0.29 10.1 0.3 0.48 9.4 0.3 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Zn_clus PF00172.18 CAR27571.1 - 1.8e-08 34.4 10.9 3.2e-08 33.6 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CAR27572.1 - 3e-30 105.4 27.2 7.5e-18 64.6 5.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CAR27572.1 - 5.6e-12 44.9 22.8 4.8e-08 32.0 6.1 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 CAR27572.1 - 0.00012 21.2 20.6 0.00033 19.6 20.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 CAR27572.1 - 0.0042 15.4 2.4 0.0042 15.4 2.4 3.4 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 CAR27572.1 - 0.0076 15.2 27.5 0.045 12.6 11.9 2.1 1 1 1 2 2 2 2 MFS_1 like family Carn_acyltransf PF00755.20 CAR27573.1 - 1.4e-102 344.2 0.0 1.7e-102 344.0 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ribosomal_S7 PF00177.21 CAR27574.1 - 2.9e-36 124.3 1.4 4e-36 123.9 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ATP-synt_ab PF00006.25 CAR27576.1 - 3.8e-62 209.7 0.0 5.6e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CAR27576.1 - 1.1e-24 86.7 0.7 3.6e-24 85.1 0.7 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 CAR27576.1 - 0.0078 15.6 0.3 0.014 14.8 0.3 1.4 1 0 0 1 1 1 1 KaiC RsgA_GTPase PF03193.16 CAR27576.1 - 0.009 15.9 0.1 0.026 14.4 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 CAR27576.1 - 0.018 14.2 0.7 0.074 12.2 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 CAR27576.1 - 0.034 14.6 0.1 0.88 10.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CAR27576.1 - 0.04 13.8 0.2 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 CAR27576.1 - 0.1 13.0 0.2 0.41 11.0 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 CAR27576.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CAR27576.1 - 0.12 12.7 0.8 0.48 10.7 0.2 2.0 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CAR27576.1 - 0.18 10.6 0.8 0.53 9.1 0.2 1.8 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain T3SS_ATPase_C PF18269.1 CAR27576.1 - 0.2 11.5 0.6 1.5 8.7 0.6 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain Pox_A32 PF04665.12 CAR27576.1 - 0.27 10.7 0.1 0.5 9.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein P5CR_dimer PF14748.6 CAR27577.1 - 1.6e-32 111.8 0.6 3.1e-32 110.9 0.6 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CAR27577.1 - 1.4e-06 28.8 0.8 5e-06 27.0 0.8 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 CAR27577.1 - 4.6e-05 23.1 0.7 0.00012 21.8 0.7 1.9 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 CAR27577.1 - 0.015 15.4 0.1 0.62 10.2 0.0 2.3 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Caps_synth_GfcC PF06251.11 CAR27577.1 - 0.082 12.5 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Capsule biosynthesis GfcC JmjC PF02373.22 CAR27578.1 - 1.3e-40 138.4 0.4 3.3e-40 137.1 0.4 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 CAR27578.1 - 9.2e-14 51.1 3.7 9.2e-14 51.1 3.7 2.5 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.17 CAR27578.1 - 3.1e-08 33.5 0.6 7.3e-08 32.2 0.1 2.0 2 0 0 2 2 2 1 jmjN domain PHD_2 PF13831.6 CAR27578.1 - 0.024 14.2 1.4 0.1 12.1 0.2 2.5 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 CAR27578.1 - 0.054 13.6 2.1 0.23 11.6 0.8 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger XFP PF03894.15 CAR27578.1 - 0.063 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase zf-HC5HC2H PF13771.6 CAR27578.1 - 0.086 13.1 1.7 0.17 12.2 0.1 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain DUF4047 PF13256.6 CAR27578.1 - 0.26 11.5 2.8 0.19 11.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) DUF4611 PF15387.6 CAR27578.1 - 0.37 11.0 4.1 2.6 8.3 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FWWh PF14922.6 CAR27578.1 - 0.86 9.5 4.5 0.58 10.1 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function E7 PF00527.18 CAR27578.1 - 0.92 9.8 6.8 0.28 11.4 0.5 2.9 3 0 0 3 3 3 0 E7 protein, Early protein Ilm1 PF10311.9 CAR27579.1 - 2.2e-10 40.4 10.4 7e-08 32.3 10.4 2.1 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Med17 PF10156.9 CAR27580.1 - 1.5e-183 610.7 12.1 1.9e-183 610.4 12.1 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Rpn3_C PF08375.11 CAR27581.1 - 1.1e-22 80.2 1.6 2.5e-22 79.1 1.6 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CAR27581.1 - 8.8e-21 74.4 0.4 2.3e-20 73.1 0.4 1.7 1 0 0 1 1 1 1 PCI domain Peptidase_M48_N PF16491.5 CAR27582.1 - 2.2e-58 197.1 8.5 2.2e-58 197.1 8.5 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CAR27582.1 - 4.9e-41 140.7 0.1 1.2e-40 139.4 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 CAR27582.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Peptidase_M1 PF01433.20 CAR27582.1 - 0.02 14.5 0.1 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M1 domain SprT-like PF10263.9 CAR27582.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 SprT-like family TRAM_LAG1_CLN8 PF03798.16 CAR27583.1 - 1.2e-29 103.5 18.1 1.2e-29 103.5 18.1 1.4 2 0 0 2 2 2 1 TLC domain PfkB PF00294.24 CAR27584.1 - 3.6e-71 239.9 0.8 4.6e-71 239.6 0.8 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CAR27584.1 - 0.00087 18.7 0.0 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Na_Ca_ex PF01699.24 CAR27585.1 - 3.5e-46 156.9 39.1 9.4e-26 90.6 12.6 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein HemY_N PF07219.13 CAR27585.1 - 0.82 9.9 2.1 4.2 7.6 0.0 3.0 3 0 0 3 3 3 0 HemY protein N-terminus Lipase_3 PF01764.25 CAR27586.1 - 5.1e-36 123.6 0.0 9.4e-36 122.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 CAR27586.1 - 0.0061 16.3 0.0 0.0098 15.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CAR27586.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 CAR27586.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase G-alpha PF00503.20 CAR27587.1 - 2.5e-108 362.4 4.1 3.2e-108 362.0 4.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CAR27587.1 - 6.1e-15 55.1 0.4 3.3e-10 39.7 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR27587.1 - 3.8e-05 23.2 1.8 0.0063 15.9 0.4 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CAR27587.1 - 0.0003 21.0 0.2 0.53 10.5 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SMP_C2CD2L PF18696.1 CAR27587.1 - 0.062 13.1 0.2 0.58 10.0 0.0 2.2 2 0 0 2 2 2 0 Synaptotagmin-like, mitochondrial and lipid-binding domain AAA_29 PF13555.6 CAR27587.1 - 0.063 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 CAR27587.1 - 0.09 12.3 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Pam17 PF08566.10 CAR27588.1 - 4.4e-65 218.5 0.0 5.3e-65 218.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Pmp3 PF01679.17 CAR27589.1 - 4.9e-16 58.7 6.1 6e-16 58.4 6.1 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator F-box-like PF12937.7 CAR27590.1 - 1.8e-07 30.9 0.3 8.3e-07 28.8 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CAR27590.1 - 0.00088 19.1 0.3 0.00088 19.1 0.3 2.3 3 0 0 3 3 3 1 F-box domain NDUF_B5 PF09781.9 CAR27590.1 - 0.082 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Zn_clus PF00172.18 CAR27591.1 - 5.1e-08 32.9 12.8 9.4e-08 32.1 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Las1 PF04031.13 CAR27592.1 - 1.3e-49 168.2 0.7 1.3e-49 168.2 0.7 2.1 2 0 0 2 2 2 1 Las1-like DUF4882 PF16223.5 CAR27592.1 - 0.022 14.0 0.4 0.11 11.7 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4882) Retrotrans_gag PF03732.17 CAR27592.1 - 0.22 11.8 13.0 1.2 9.5 0.5 3.6 2 2 1 3 3 3 0 Retrotransposon gag protein PcfK PF14058.6 CAR27592.1 - 8.6 6.6 9.1 0.96 9.7 0.4 3.1 4 0 0 4 4 4 0 PcfK-like protein RNA_polI_A34 PF08208.11 CAR27593.1 - 1.1e-25 91.0 11.6 1.8e-25 90.2 11.6 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 TFA2_Winged_2 PF18121.1 CAR27594.1 - 1.7e-21 75.7 2.1 2.3e-21 75.2 0.1 2.2 2 1 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 CAR27594.1 - 8.3e-17 61.2 0.9 1.7e-16 60.2 0.9 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain Pox_Ag35 PF03286.14 CAR27594.1 - 6.7e-06 26.0 3.6 6.7e-06 26.0 3.6 1.9 2 0 0 2 2 2 1 Pox virus Ag35 surface protein ORC6 PF05460.13 CAR27594.1 - 0.035 13.4 2.6 0.05 12.9 2.6 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF1987 PF09345.10 CAR27594.1 - 0.15 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Glyco_hydro_70 PF02324.16 CAR27595.1 - 0.0073 14.6 1.0 0.012 13.9 0.5 1.4 1 1 1 2 2 2 1 Glycosyl hydrolase family 70 Lipase_GDSL_lke PF16255.5 CAR27595.1 - 0.031 13.6 0.1 0.1 11.9 0.0 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase DUF948 PF06103.11 CAR27595.1 - 0.4 11.0 1.7 17 5.8 0.1 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 CAR27595.1 - 2.7 8.7 6.3 1.1 9.9 0.2 3.1 2 1 0 2 2 2 0 SlyX CRAL_TRIO PF00650.20 CAR27597.1 - 5.2e-25 88.0 0.6 1.3e-24 86.7 0.2 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain DUF3139 PF11337.8 CAR27597.1 - 0.0049 17.5 4.3 0.17 12.6 0.1 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3139) CRAL_TRIO_N PF03765.15 CAR27597.1 - 0.038 14.2 0.2 0.12 12.5 0.2 1.9 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain RAMP PF04901.13 CAR27597.1 - 0.057 13.4 0.5 0.36 10.8 0.1 2.2 2 0 0 2 2 2 0 Receptor activity modifying family BATS PF06968.13 CAR27598.1 - 2.4e-22 78.9 0.5 9.5e-22 76.9 0.0 2.0 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 CAR27598.1 - 1.6e-15 57.9 0.1 1.4e-14 54.8 0.1 2.0 2 0 0 2 2 2 1 Radical SAM superfamily INPP5B_PH PF16776.5 CAR27598.1 - 0.0032 17.2 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Ank_2 PF12796.7 CAR27600.1 - 3.5e-30 104.4 0.2 1e-14 54.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAR27600.1 - 3.4e-27 94.2 4.6 4.8e-09 36.3 0.6 4.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CAR27600.1 - 6.9e-27 93.5 0.1 8.3e-12 45.4 0.1 5.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAR27600.1 - 1.9e-20 70.8 0.0 1.8e-07 30.9 0.2 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 CAR27600.1 - 3.3e-20 71.6 3.6 6.1e-08 32.8 0.6 5.8 6 0 0 6 6 6 4 Ankyrin repeat TFIIA PF03153.13 CAR27600.1 - 0.41 10.6 41.1 0.74 9.7 6.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit COX4 PF02936.14 CAR27601.1 - 2.9e-33 114.8 0.1 3.3e-33 114.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 CAR27601.1 - 0.023 15.2 0.3 0.04 14.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) DUF1289 PF06945.13 CAR27601.1 - 0.18 11.7 1.1 8.2 6.3 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Methyltransf_16 PF10294.9 CAR27602.1 - 0.04 13.7 0.1 0.69 9.6 0.0 2.3 1 1 0 2 2 2 0 Lysine methyltransferase COG5 PF10392.9 CAR27603.1 - 2.9e-38 131.0 1.4 2.9e-38 131.0 1.4 3.4 2 1 2 4 4 4 1 Golgi transport complex subunit 5 CorA PF01544.18 CAR27603.1 - 0.0027 17.1 7.9 0.0036 16.7 3.8 2.4 1 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF2011 PF09428.10 CAR27604.1 - 5.5e-22 77.8 0.0 9.5e-22 77.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Sec23_trunk PF04811.15 CAR27605.1 - 1e-69 234.8 0.1 3.5e-69 233.1 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CAR27605.1 - 1e-19 70.2 0.2 2.7e-19 68.9 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CAR27605.1 - 5.9e-15 55.0 5.5 1.1e-14 54.1 5.5 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CAR27605.1 - 2.8e-13 50.4 0.2 8e-13 48.9 0.2 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CAR27605.1 - 2.5e-10 40.1 0.0 5.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CAR27605.1 - 0.17 11.3 0.0 0.42 10.0 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Metallopep PF12044.8 CAR27606.1 - 1.8e-167 557.3 0.0 2.2e-167 557.0 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 CAR27606.1 - 0.00065 19.6 0.1 0.0035 17.3 0.0 2.1 1 1 1 2 2 2 1 Jacalin-like lectin domain Reprolysin_3 PF13582.6 CAR27606.1 - 0.028 15.0 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CAR27606.1 - 0.029 14.5 0.2 0.051 13.7 0.2 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 CAR27606.1 - 0.09 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Matrixin 6PF2K PF01591.18 CAR27607.1 - 3.9e-81 271.6 0.0 3.9e-81 271.6 0.0 2.0 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CAR27607.1 - 2.7e-29 102.3 0.0 3.9e-27 95.2 0.0 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CAR27607.1 - 1.7e-08 34.7 0.0 4.9e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CAR27607.1 - 0.00091 19.7 0.0 0.0043 17.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR27607.1 - 0.00092 19.8 0.0 0.00092 19.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain APS_kinase PF01583.20 CAR27607.1 - 0.0056 16.6 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.10 CAR27607.1 - 0.016 14.7 1.6 0.018 14.5 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Mob1_phocein PF03637.17 CAR27608.1 - 8.3e-69 230.9 0.7 1.2e-68 230.5 0.7 1.2 1 0 0 1 1 1 1 Mob1/phocein family ALG11_N PF15924.5 CAR27609.1 - 2.2e-80 269.7 1.5 3.4e-80 269.0 1.5 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CAR27609.1 - 1.2e-14 54.2 0.0 2.2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CAR27609.1 - 3.3e-05 23.9 0.0 6.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CAR27609.1 - 0.00076 19.9 0.0 0.0023 18.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 PH PF00169.29 CAR27610.1 - 1.4e-10 41.6 0.1 3.1e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 PH domain RTT107_BRCT_5 PF16770.5 CAR27610.1 - 0.034 14.0 0.2 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain CDC45 PF02724.14 CAR27610.1 - 2.3 6.4 7.8 3.5 5.8 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein LMP PF04778.12 CAR27610.1 - 3 7.7 7.9 0.36 10.7 1.5 2.5 2 1 1 3 3 3 0 LMP repeated region Peptidase_M1 PF01433.20 CAR27611.1 - 1.4e-49 168.7 0.2 2e-49 168.1 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CAR27611.1 - 6.1e-35 119.7 1.0 1.2e-34 118.7 0.1 2.1 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CAR27611.1 - 3.7e-29 102.2 0.0 7.5e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain UTP15_C PF09384.10 CAR27611.1 - 0.14 11.9 0.0 0.42 10.3 0.1 1.7 2 0 0 2 2 2 0 UTP15 C terminal PRA1 PF03208.19 CAR27612.1 - 4.1e-39 133.5 1.3 5.1e-39 133.2 1.3 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 CAR27612.1 - 0.087 11.6 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2722 PF10846.8 CAR27613.1 - 1.2e-42 146.5 40.9 2.9e-42 145.2 40.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) SHQ1 PF04925.15 CAR27614.1 - 3.2e-69 232.0 0.3 4.8e-69 231.4 0.3 1.3 1 0 0 1 1 1 1 SHQ1 protein Diphthamide_syn PF01866.17 CAR27615.1 - 6.5e-114 380.4 0.0 8.1e-114 380.1 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein COG6 PF06419.11 CAR27616.1 - 2e-156 521.8 27.2 2.9e-156 521.3 27.2 1.2 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 zf-AD PF07776.15 CAR27616.1 - 0.26 11.6 1.7 2.7 8.3 0.1 3.5 4 0 0 4 4 4 0 Zinc-finger associated domain (zf-AD) Arteri_nsp7a PF16749.5 CAR27616.1 - 0.4 10.9 1.5 14 5.9 0.1 2.7 2 0 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha DUF722 PF05263.11 CAR27616.1 - 5.5 7.2 8.8 2.7 8.2 0.9 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF722) Pro_CA PF00484.19 CAR27618.1 - 2.1e-38 132.1 0.3 2.6e-38 131.8 0.3 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Erp_C PF06780.11 CAR27618.1 - 0.18 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Erp protein C-terminus Glyco_hydro_15 PF00723.21 CAR27619.1 - 4.2e-59 200.5 0.0 5.9e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Complex1_LYR_2 PF13233.6 CAR27620.1 - 3.2e-20 72.7 5.4 1.6e-19 70.4 5.4 1.9 1 1 0 1 1 1 1 Complex1_LYR-like DUF3584 PF12128.8 CAR27620.1 - 0.011 13.4 6.3 0.012 13.2 6.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1993 PF09351.10 CAR27620.1 - 0.046 13.9 1.6 0.059 13.5 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) Aldo_ket_red PF00248.21 CAR27621.1 - 4.5e-63 213.2 0.0 5.1e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA_assoc_C PF09821.9 CAR27621.1 - 0.014 16.0 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 C-terminal AAA-associated domain Iso_dh PF00180.20 CAR27622.1 - 8.2e-76 255.4 0.4 1e-75 255.1 0.4 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CLTH PF10607.9 CAR27623.1 - 1.8e-29 102.5 0.5 1.8e-29 102.5 0.5 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain TPR_1 PF00515.28 CAR27623.1 - 0.091 12.6 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat SSXT PF05030.12 CAR27623.1 - 0.12 12.0 0.7 0.36 10.5 0.7 1.8 1 0 0 1 1 1 0 SSXT protein (N-terminal region) DUF2431 PF10354.9 CAR27624.1 - 4e-57 193.2 0.1 6.4e-57 192.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) PIG-H PF10181.9 CAR27625.1 - 1.2e-18 66.8 0.3 2.6e-18 65.7 0.3 1.6 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Myb_DNA-bind_7 PF15963.5 CAR27626.1 - 2.5e-25 88.2 0.0 2.5e-25 88.2 0.0 3.0 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CAR27626.1 - 6.7e-09 35.8 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR27626.1 - 0.00056 20.1 0.1 0.0021 18.3 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain K_oxygenase PF13434.6 CAR27626.1 - 0.11 11.6 2.4 3.7 6.6 0.2 2.5 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF2981 PF11200.8 CAR27626.1 - 1.7 8.3 7.6 0.21 11.3 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2981) NOA36 PF06524.12 CAR27626.1 - 7.8 5.7 9.1 21 4.3 9.1 1.7 1 0 0 1 1 1 0 NOA36 protein Tim17 PF02466.19 CAR27627.1 - 2.9e-31 108.1 6.8 3.7e-31 107.8 6.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 CAR27628.1 - 4.4e-48 164.0 0.0 2.5e-47 161.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27628.1 - 9.4e-23 80.8 0.0 2.1e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR27628.1 - 0.01 15.7 0.1 0.01 15.7 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 CAR27628.1 - 0.023 14.3 0.0 0.023 14.3 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Activator_LAG-3 PF11498.8 CAR27628.1 - 0.067 12.2 30.2 3.5 6.5 27.9 2.2 1 1 1 2 2 2 0 Transcriptional activator LAG-3 Choline_kinase PF01633.20 CAR27628.1 - 0.13 11.9 0.0 0.13 11.9 0.0 2.1 2 1 0 2 2 2 0 Choline/ethanolamine kinase RNA_pol_Rpb4 PF03874.16 CAR27629.1 - 2.8e-36 124.5 3.8 2.8e-36 124.5 3.8 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb4 RPN2_C PF18004.1 CAR27629.1 - 0.42 10.5 3.8 0.14 12.1 0.7 1.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Glyco_transf_15 PF01793.16 CAR27630.1 - 4.4e-111 371.2 13.5 5.4e-111 371.0 13.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L1 PF00687.21 CAR27631.1 - 7.6e-45 153.2 1.0 8.7e-45 153.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DEAD PF00270.29 CAR27632.1 - 6.3e-44 149.8 0.5 6.3e-44 149.8 0.5 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR27632.1 - 6.3e-31 107.0 0.4 4e-30 104.4 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR27632.1 - 1.1e-07 32.0 0.0 2.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CAR27632.1 - 0.00071 19.9 0.1 0.0084 16.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAR27632.1 - 0.011 15.5 0.1 0.023 14.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain Glyco_transf_8 PF01501.20 CAR27633.1 - 2.2e-31 109.4 0.1 2.3e-30 106.0 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Med3 PF11593.8 CAR27633.1 - 6.1 5.9 8.9 9 5.4 8.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_S21e PF01249.18 CAR27634.1 - 5.1e-40 135.5 0.0 5.6e-40 135.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA_U5-meth_tr PF05958.11 CAR27635.1 - 1.2e-21 77.1 0.2 1.5e-20 73.5 0.2 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 CAR27635.1 - 9.2e-09 35.3 0.0 2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR27635.1 - 1.2e-06 29.2 0.0 2.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CAR27635.1 - 1.4e-05 24.7 0.1 2.5e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRAM PF01938.20 CAR27635.1 - 3.1e-05 23.9 0.1 5.4e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 TRAM domain Methyltransf_15 PF09445.10 CAR27635.1 - 0.00046 19.8 0.0 0.00097 18.7 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 CAR27635.1 - 0.00072 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 CAR27635.1 - 0.00092 19.8 0.0 0.0026 18.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR27635.1 - 0.00099 18.5 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 CAR27635.1 - 0.0098 15.7 0.2 0.056 13.2 0.0 2.2 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_23 PF13489.6 CAR27635.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ras PF00071.22 CAR27636.1 - 5.2e-48 162.7 0.0 6.7e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR27636.1 - 1.1e-22 80.4 0.0 1.8e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR27636.1 - 1.8e-05 24.3 0.0 2.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF4601 PF15373.6 CAR27636.1 - 0.022 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4601) AAA_6 PF12774.7 CAR27637.1 - 4.4e-109 364.4 1.4 2.9e-105 351.9 1.0 4.7 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CAR27637.1 - 4.7e-81 272.9 12.2 4.7e-81 272.9 12.2 6.9 7 1 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CAR27637.1 - 6.6e-58 196.7 6.0 1.3e-56 192.4 15.3 5.9 5 3 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 AAA_9 PF12781.7 CAR27637.1 - 4e-54 183.1 0.2 4e-54 183.1 0.2 4.4 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 CAR27637.1 - 2.3e-42 145.1 4.4 4e-42 144.3 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CAR27637.1 - 8.7e-39 132.9 1.4 1.5e-31 109.3 0.0 4.4 4 0 0 4 4 4 3 P-loop containing dynein motor region MT PF12777.7 CAR27637.1 - 1.4e-23 83.5 9.1 2.6e-23 82.6 9.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CAR27637.1 - 1.9e-22 79.7 0.8 2.6e-07 30.7 0.0 6.1 4 2 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 CAR27637.1 - 2.6e-17 63.1 1.0 1.5e-16 60.6 0.0 2.8 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 CAR27637.1 - 2.2e-15 57.2 1.6 0.0022 18.4 0.0 6.6 6 0 0 6 6 4 3 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 CAR27637.1 - 3.8e-15 56.0 0.0 6.1e-14 52.1 0.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 CAR27637.1 - 1e-13 51.7 6.7 0.0045 17.3 0.0 6.8 5 1 1 6 6 6 3 AAA domain AAA_16 PF13191.6 CAR27637.1 - 2e-10 41.3 1.5 0.18 12.2 0.0 6.4 5 1 0 6 6 5 3 AAA ATPase domain AAA_18 PF13238.6 CAR27637.1 - 2e-09 38.0 1.2 0.17 12.4 0.0 5.8 5 0 0 5 5 4 2 AAA domain T2SSE PF00437.20 CAR27637.1 - 8e-08 31.7 0.1 0.027 13.5 0.3 4.0 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_19 PF13245.6 CAR27637.1 - 8.1e-08 32.7 0.1 0.14 12.5 0.0 4.7 4 0 0 4 4 4 2 AAA domain AAA_24 PF13479.6 CAR27637.1 - 3.2e-07 30.3 1.0 0.36 10.5 0.0 5.5 6 0 0 6 6 6 1 AAA domain AAA_30 PF13604.6 CAR27637.1 - 8e-07 29.0 0.2 0.81 9.4 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_14 PF13173.6 CAR27637.1 - 1.6e-06 28.2 9.0 0.18 11.8 0.0 7.3 7 0 0 7 7 6 1 AAA domain AAA_lid_1 PF17857.1 CAR27637.1 - 2.2e-06 27.8 0.3 5.2e-05 23.4 0.0 3.5 3 0 0 3 3 2 1 AAA+ lid domain AAA_33 PF13671.6 CAR27637.1 - 6.7e-06 26.3 0.0 0.47 10.6 0.0 4.7 4 0 0 4 4 4 1 AAA domain Rad17 PF03215.15 CAR27637.1 - 0.00027 20.9 6.1 0.17 11.8 0.1 5.1 5 0 0 5 5 4 1 Rad17 P-loop domain IstB_IS21 PF01695.17 CAR27637.1 - 0.00036 20.3 0.0 0.24 11.1 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein RuvB_N PF05496.12 CAR27637.1 - 0.00039 20.2 0.0 2.2 8.0 0.0 4.5 5 0 0 5 5 4 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CAR27637.1 - 0.00052 20.0 1.6 5.3 7.1 0.1 4.5 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CAR27637.1 - 0.0013 19.1 0.2 13 6.2 0.0 4.5 4 0 0 4 4 3 0 RNA helicase ABC_tran PF00005.27 CAR27637.1 - 0.004 17.7 1.4 2.2 8.8 0.0 4.2 3 0 0 3 3 2 1 ABC transporter Zeta_toxin PF06414.12 CAR27637.1 - 0.0089 15.3 0.0 9.8 5.4 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin cobW PF02492.19 CAR27637.1 - 0.01 15.5 1.6 0.25 10.9 0.0 2.9 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 CAR27637.1 - 0.01 16.1 0.0 18 5.5 0.0 4.0 4 0 0 4 4 3 0 AAA domain DEAD PF00270.29 CAR27637.1 - 0.017 14.9 0.1 12 5.7 0.0 3.9 3 0 0 3 3 3 0 DEAD/DEAH box helicase NACHT PF05729.12 CAR27637.1 - 0.033 14.1 4.2 5.3 6.9 0.1 4.1 4 0 0 4 4 4 0 NACHT domain Mg_chelatase PF01078.21 CAR27637.1 - 0.049 13.0 3.8 0.7 9.2 0.0 3.7 5 0 0 5 5 4 0 Magnesium chelatase, subunit ChlI FAD_SOX PF18371.1 CAR27637.1 - 0.06 13.7 0.1 2.7 8.4 0.0 4.1 2 0 0 2 2 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase FtsK_SpoIIIE PF01580.18 CAR27637.1 - 0.089 12.1 0.1 26 4.1 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_25 PF13481.6 CAR27637.1 - 0.16 11.6 0.0 2.5 7.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain MA3 PF02847.17 CAR27637.1 - 0.3 11.1 12.0 35 4.4 0.1 7.2 8 0 0 8 8 5 0 MA3 domain NTPase_1 PF03266.15 CAR27637.1 - 2.5 8.0 9.8 11 5.9 0.4 4.2 5 0 0 5 5 2 0 NTPase PAP2 PF01569.21 CAR27638.1 - 1.4e-16 60.5 1.8 1.4e-16 60.5 1.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CAR27638.1 - 0.093 12.4 5.4 0.22 11.2 5.4 1.8 1 1 0 1 1 1 0 PAP2 superfamily DUF212 PF02681.14 CAR27638.1 - 0.1 12.7 0.5 0.31 11.2 0.2 1.9 1 1 0 1 1 1 0 Divergent PAP2 family Fer4_5 PF12801.7 CAR27638.1 - 8.2 6.5 9.1 0.25 11.3 0.4 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Mito_carr PF00153.27 CAR27639.1 - 2.7e-60 200.3 2.9 3.2e-20 71.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Solute_trans_a PF03619.16 CAR27640.1 - 4.8e-73 246.0 13.4 6.2e-73 245.6 13.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Zn_dep_PLPC PF00882.18 CAR27641.1 - 6.1e-26 91.5 0.1 1e-25 90.8 0.1 1.3 1 0 0 1 1 1 1 Zinc dependent phospholipase C FG-GAP PF01839.23 CAR27641.1 - 0.015 15.4 0.3 0.85 9.8 0.1 2.8 2 0 0 2 2 2 0 FG-GAP repeat VCBS PF13517.6 CAR27641.1 - 0.031 14.8 0.1 0.14 12.8 0.1 2.2 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella mIF3 PF14877.6 CAR27642.1 - 2.3e-64 216.3 8.9 2.3e-64 216.3 8.9 2.2 2 0 0 2 2 2 1 Mitochondrial translation initiation factor CPSase_L_D2 PF02786.17 CAR27643.1 - 2.6e-115 383.2 1.4 1.3e-83 279.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CAR27643.1 - 2.1e-49 166.6 0.0 5.8e-49 165.2 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CAR27643.1 - 3e-46 157.6 0.0 7e-46 156.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 CAR27643.1 - 7.6e-45 152.6 0.1 1.7e-44 151.4 0.1 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 CAR27643.1 - 1.3e-38 132.1 0.0 3.7e-38 130.6 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CAR27643.1 - 7.1e-28 97.7 0.0 3.2e-27 95.5 0.0 2.2 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 CAR27643.1 - 2.3e-21 75.8 0.0 1.1e-20 73.6 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 CAR27643.1 - 1.3e-18 67.3 2.2 6.2e-10 38.9 0.7 2.7 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CAR27643.1 - 3.8e-15 55.9 0.4 8.6e-07 28.7 0.2 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CAR27643.1 - 4.9e-12 45.7 0.1 9.8e-07 28.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 CAR27643.1 - 1.5e-05 24.9 0.0 0.003 17.4 0.0 2.7 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 CAR27643.1 - 0.00011 22.3 1.4 0.22 11.5 0.3 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 CAR27643.1 - 0.00063 19.6 0.2 0.065 13.0 0.0 3.9 4 0 0 4 4 4 1 DJ-1/PfpI family RimK PF08443.11 CAR27643.1 - 0.008 15.8 0.1 0.3 10.7 0.3 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain NBD_C PF17042.5 CAR27643.1 - 0.057 13.9 0.1 17 5.9 0.0 3.0 2 1 0 3 3 3 0 Nucleotide-binding C-terminal domain TrkH PF02386.16 CAR27644.1 - 4.7e-169 563.0 0.5 7.6e-168 559.0 0.0 2.1 2 0 0 2 2 2 1 Cation transport protein DUF3209 PF11483.8 CAR27644.1 - 0.079 13.4 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) DNA_pol_viral_C PF00336.18 CAR27644.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Vitellogenin_N PF01347.22 CAR27644.1 - 0.25 9.7 4.6 0.47 8.8 4.6 1.4 1 0 0 1 1 1 0 Lipoprotein amino terminal region PI3K_1B_p101 PF10486.9 CAR27644.1 - 1.2 6.8 10.6 2 6.1 10.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pkinase PF00069.25 CAR27645.1 - 2.9e-60 203.9 0.0 4.1e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27645.1 - 3.5e-38 131.4 0.0 5e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR27645.1 - 7.9e-05 22.1 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAR27645.1 - 0.01 14.7 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 CAR27645.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-H2C2 PF09337.10 CAR27646.1 - 6.4e-12 45.5 1.3 1.2e-11 44.6 1.3 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 CAR27646.1 - 2.5e-09 37.1 0.2 4.4e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 CAR27646.1 - 2.2e-05 24.6 0.5 0.00011 22.4 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family BUD22 PF09073.10 CAR27646.1 - 0.063 12.6 17.0 0.11 11.8 17.0 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 CAR27646.1 - 0.48 9.8 25.1 1.2 8.5 25.1 1.6 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CAR27646.1 - 0.56 8.4 25.6 0.81 7.8 25.6 1.1 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.6 CAR27646.1 - 0.6 8.8 7.3 0.93 8.2 7.3 1.2 1 0 0 1 1 1 0 Raftlin RPN2_C PF18004.1 CAR27646.1 - 3.8 7.4 13.6 11 6.0 13.6 1.8 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF2457 PF10446.9 CAR27646.1 - 4.8 6.2 23.1 7.5 5.6 23.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CN_hydrolase PF00795.22 CAR27647.1 - 2.9e-56 190.7 0.0 3.3e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ATP-synt_F6 PF05511.11 CAR27647.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 GCD14 PF08704.10 CAR27648.1 - 3.5e-79 266.0 0.0 3e-78 262.9 0.0 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CAR27648.1 - 0.00074 19.3 0.0 0.0013 18.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR27648.1 - 0.012 16.3 0.0 0.028 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 CAR27648.1 - 0.018 14.1 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 CAR27648.1 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14_N PF14801.6 CAR27648.1 - 0.03 14.1 0.0 0.088 12.7 0.0 1.8 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Gcd10p PF04189.13 CAR27648.1 - 0.065 12.3 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Gcd10p family LSM PF01423.22 CAR27649.1 - 2.4e-15 56.0 0.1 3.8e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 LSM domain DUF4426 PF14467.6 CAR27649.1 - 0.054 13.5 0.2 0.13 12.2 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4426) DUF1687 PF07955.11 CAR27650.1 - 4.1e-27 95.2 0.6 5.1e-27 94.9 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) DUF5427 PF10310.9 CAR27651.1 - 7e-118 394.5 30.4 8.3e-118 394.3 30.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Alb1 PF09135.11 CAR27652.1 - 1.1e-15 58.4 8.5 1.7e-15 57.7 8.5 1.3 1 0 0 1 1 1 1 Alb1 ALC PF17527.2 CAR27652.1 - 0.44 10.2 6.1 1.1 8.9 0.0 2.1 1 1 1 2 2 2 0 Phage ALC protein DUF3073 PF11273.8 CAR27652.1 - 3.6 8.4 10.2 0.3 11.9 4.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3073) Ribul_P_3_epim PF00834.19 CAR27653.1 - 5.9e-69 231.4 0.0 1e-68 230.7 0.0 1.3 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 CAR27653.1 - 0.031 13.6 0.1 0.043 13.1 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 CAR27653.1 - 0.05 13.2 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Glyoxalase_6 PF18029.1 CAR27653.1 - 0.093 13.5 0.0 5.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain NAP PF00956.18 CAR27654.1 - 5.7e-86 288.0 7.8 5.7e-86 288.0 7.8 2.3 3 0 0 3 3 3 1 Nucleosome assembly protein (NAP) BSP_II PF05432.11 CAR27654.1 - 0.0038 17.0 1.3 0.0038 17.0 1.3 3.9 3 1 0 4 4 4 1 Bone sialoprotein II (BSP-II) RFX5_N PF18326.1 CAR27654.1 - 0.12 12.1 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 RFX5 N-terminal domain BUD22 PF09073.10 CAR27654.1 - 3 7.1 37.0 0.96 8.7 3.2 2.6 2 1 0 2 2 2 0 BUD22 PET10 PF17316.2 CAR27655.1 - 3.6e-102 341.2 0.1 4.4e-102 340.9 0.1 1.1 1 0 0 1 1 1 1 Petite colonies protein 10 SelP_N PF04592.14 CAR27656.1 - 0.48 9.8 10.9 1.1 8.6 10.9 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pho86 PF11124.8 CAR27657.1 - 2.3e-98 329.3 1.3 2.6e-98 329.1 1.3 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Lectin_leg-like PF03388.13 CAR27658.1 - 9.4e-13 48.0 0.0 3.7e-08 33.0 0.0 2.3 2 0 0 2 2 2 2 Legume-like lectin family His_Phos_1 PF00300.22 CAR27659.1 - 3.6e-33 114.9 0.1 4.8e-33 114.5 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CAR27659.1 - 0.03 13.7 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) SUN PF03856.13 CAR27660.1 - 5.6e-92 307.6 17.4 7.6e-92 307.2 17.4 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) bMG3 PF11974.8 CAR27660.1 - 0.05 13.6 0.3 0.2 11.7 0.0 2.2 2 1 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain Miga PF10265.9 CAR27660.1 - 1.6 7.6 7.8 2.2 7.1 7.8 1.1 1 0 0 1 1 1 0 Mitoguardin Apt1 PF10351.9 CAR27660.1 - 2.4 6.9 7.1 3.1 6.5 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 CAR27660.1 - 3.9 7.3 10.7 5.4 6.8 10.7 1.1 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CAR27660.1 - 7.9 4.9 9.9 10 4.5 9.9 1.1 1 0 0 1 1 1 0 Macoilin family SnAPC_2_like PF11035.8 CAR27660.1 - 9.5 6.3 7.9 14 5.7 7.9 1.3 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb ASF1_hist_chap PF04729.13 CAR27661.1 - 2.8e-71 238.5 0.1 2.8e-71 238.5 0.1 1.5 2 0 0 2 2 2 1 ASF1 like histone chaperone CDC45 PF02724.14 CAR27661.1 - 0.0041 15.5 31.3 0.0055 15.1 31.3 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 CAR27661.1 - 0.0075 14.5 35.1 0.0086 14.4 35.1 1.0 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 CAR27661.1 - 0.014 13.9 33.0 0.019 13.5 33.0 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 CAR27661.1 - 0.045 13.2 36.7 0.055 12.9 36.7 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CAR27661.1 - 0.1 11.9 33.8 0.11 11.8 33.8 1.1 1 0 0 1 1 1 0 BUD22 Merozoite_SPAM PF07133.11 CAR27661.1 - 0.15 12.1 51.2 0.26 11.3 51.2 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) RR_TM4-6 PF06459.12 CAR27661.1 - 0.6 9.9 20.0 0.84 9.4 20.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cwf_Cwc_15 PF04889.12 CAR27661.1 - 0.68 9.6 31.3 1 9.0 31.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CCSAP PF15748.5 CAR27661.1 - 1.2 9.2 17.1 1.7 8.7 17.1 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated PA26 PF04636.13 CAR27661.1 - 1.3 7.8 4.4 1.6 7.6 4.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SpoIIP PF07454.11 CAR27661.1 - 2.8 7.3 20.0 4.3 6.7 20.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Hid1 PF12722.7 CAR27661.1 - 2.8 6.0 13.8 3.7 5.5 13.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SAPS PF04499.15 CAR27661.1 - 3.6 6.3 17.1 4.3 6.0 17.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_polI_A34 PF08208.11 CAR27661.1 - 5.7 7.0 27.1 9.3 6.3 27.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 YL1 PF05764.13 CAR27661.1 - 5.7 7.0 37.8 7.7 6.5 37.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DnaJ PF00226.31 CAR27662.1 - 0.0033 17.5 0.1 0.0082 16.3 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain AA_permease PF00324.21 CAR27663.1 - 4.8e-155 516.8 36.7 5.5e-155 516.6 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR27663.1 - 6.7e-41 140.5 37.9 9e-41 140.1 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 CAR27663.1 - 1.8 7.3 5.5 0.23 10.2 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) Peptidase_M22 PF00814.25 CAR27664.1 - 7.8e-83 278.3 0.0 9.9e-83 278.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family YjbR PF04237.13 CAR27664.1 - 0.16 12.6 0.0 7.7 7.1 0.0 2.3 2 0 0 2 2 2 0 YjbR DASH_Spc34 PF08657.10 CAR27665.1 - 9.9e-87 290.9 0.6 1.1e-86 290.7 0.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 PRKG1_interact PF15898.5 CAR27665.1 - 0.066 14.1 8.3 0.12 13.3 8.3 1.4 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF1843 PF08898.10 CAR27665.1 - 1.9 9.0 6.6 5.3 7.6 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF1192 PF06698.11 CAR27665.1 - 3.5 7.8 7.4 2.3 8.4 1.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) WD40 PF00400.32 CAR27666.1 - 1.6e-28 98.3 8.9 4.8e-06 27.2 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.8 CAR27666.1 - 5.8e-10 38.4 5.3 5.3e-05 22.1 0.1 4.9 1 1 4 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CAR27666.1 - 1.1e-07 32.0 0.0 0.014 15.7 0.0 4.8 3 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Caf4 PF11615.8 CAR27666.1 - 1.9e-06 27.7 0.3 0.00039 20.3 0.1 2.8 2 0 0 2 2 2 1 CCR4-associated factor 4 Mdv1 PF11542.8 CAR27666.1 - 0.00042 20.2 1.0 0.00094 19.1 1.0 1.5 1 0 0 1 1 1 1 Mitochondrial division protein 1 BBS2_Mid PF14783.6 CAR27666.1 - 0.0032 17.5 0.3 0.059 13.4 0.0 3.0 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 CAR27666.1 - 0.024 14.2 0.9 3.9 7.0 0.3 2.3 2 0 0 2 2 2 0 PQQ-like domain HSP20 PF00011.21 CAR27666.1 - 0.042 14.0 0.1 0.19 11.9 0.0 2.1 2 0 0 2 2 2 0 Hsp20/alpha crystallin family Cpn60_TCP1 PF00118.24 CAR27667.1 - 4.9e-155 516.9 3.7 5.6e-155 516.7 3.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Snf7 PF03357.21 CAR27668.1 - 2.9e-10 40.0 16.5 4.7e-10 39.3 16.5 1.3 1 0 0 1 1 1 1 Snf7 T7SS_ESX_EspC PF10824.8 CAR27668.1 - 0.031 14.7 0.1 0.031 14.7 0.1 2.1 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm DUF948 PF06103.11 CAR27668.1 - 0.52 10.6 7.1 1.5 9.1 0.3 2.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) GATA PF00320.27 CAR27669.1 - 1.7e-14 53.1 1.9 3.9e-14 52.0 1.9 1.7 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CAR27669.1 - 0.056 13.0 0.9 0.12 11.9 0.9 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 CAR27669.1 - 0.093 12.9 0.8 0.16 12.1 0.8 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GCR1_C PF12550.8 CAR27670.1 - 1.5e-21 76.5 0.3 4e-21 75.1 0.3 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NDC10_II PF16787.5 CAR27670.1 - 1.1e-11 44.4 4.0 1.5e-05 24.3 0.1 2.4 1 1 1 2 2 2 2 Centromere DNA-binding protein complex CBF3 subunit, domain 2 AAA PF00004.29 CAR27671.1 - 4e-42 143.8 0.0 9.3e-42 142.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR27671.1 - 8e-12 44.8 0.1 2.1e-11 43.4 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CAR27671.1 - 4.7e-07 30.1 0.6 8.8e-07 29.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 CAR27671.1 - 6.9e-07 29.2 0.0 3.3e-06 27.0 0.0 2.3 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CAR27671.1 - 2.1e-05 24.4 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CAR27671.1 - 0.00016 21.0 1.4 0.00016 21.0 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 CAR27671.1 - 0.00023 21.4 0.3 0.0026 18.0 0.3 2.6 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 CAR27671.1 - 0.00091 18.7 0.1 1.1 8.7 0.0 2.6 1 1 1 2 2 2 2 Bacterial TniB protein AAA_5 PF07728.14 CAR27671.1 - 0.00094 19.2 0.1 0.014 15.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CAR27671.1 - 0.0022 18.0 0.4 0.011 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CAR27671.1 - 0.0033 16.8 0.1 0.0077 15.6 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 CAR27671.1 - 0.0061 17.0 1.3 0.054 13.9 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 CAR27671.1 - 0.0077 15.8 0.0 0.55 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CAR27671.1 - 0.0089 16.5 1.3 0.12 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CAR27671.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 CAR27671.1 - 0.02 14.4 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CAR27671.1 - 0.02 15.0 0.1 0.071 13.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CAR27671.1 - 0.023 14.5 5.3 0.99 9.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Tis11B_N PF04553.12 CAR27671.1 - 0.027 15.0 0.1 0.093 13.3 0.1 1.9 1 0 0 1 1 1 0 Tis11B like protein, N terminus AAA_18 PF13238.6 CAR27671.1 - 0.04 14.5 0.0 0.04 14.5 0.0 2.6 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.6 CAR27671.1 - 0.044 13.5 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CAR27671.1 - 0.061 13.0 0.0 0.52 10.0 0.0 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 CAR27671.1 - 0.065 12.6 0.7 4.1 6.7 0.1 2.5 1 1 1 2 2 2 0 KaiC NACHT PF05729.12 CAR27671.1 - 0.078 12.9 0.1 1.9 8.4 0.1 2.4 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 CAR27671.1 - 0.13 11.7 0.0 0.53 9.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 CAR27671.1 - 0.15 12.5 0.1 0.47 10.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Glyco_transf_15 PF01793.16 CAR27672.1 - 1.4e-105 353.2 7.7 1.7e-105 352.9 7.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase UCH PF00443.29 CAR27673.1 - 2.6e-34 118.9 0.0 1.5e-31 109.8 0.0 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pox_F15 PF04596.12 CAR27673.1 - 0.026 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Poxvirus protein F15 SH3_1 PF00018.28 CAR27674.1 - 2.2e-22 78.4 0.2 6.2e-10 38.5 0.0 3.3 4 0 0 4 4 4 2 SH3 domain PX PF00787.24 CAR27674.1 - 1.4e-12 47.6 0.0 2.9e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.6 CAR27674.1 - 9.6e-08 31.8 2.1 9.8e-05 22.1 0.0 3.3 4 0 0 4 4 4 2 Variant SH3 domain SH3_2 PF07653.17 CAR27674.1 - 4.4e-07 29.5 0.1 4.9e-06 26.1 0.0 2.6 3 0 0 3 3 3 1 Variant SH3 domain PB1 PF00564.24 CAR27674.1 - 0.00047 20.0 0.1 0.001 19.0 0.1 1.5 1 0 0 1 1 1 1 PB1 domain Med3 PF11593.8 CAR27674.1 - 0.086 12.0 5.2 0.15 11.2 5.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 CAR27674.1 - 0.29 10.7 11.0 0.53 9.8 11.0 1.4 1 0 0 1 1 1 0 Spt20 family Morc6_S5 PF17942.1 CAR27675.1 - 0.019 15.0 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Morc6 ribosomal protein S5 domain 2-like VPS9 PF02204.18 CAR27676.1 - 4.1e-19 68.7 1.2 7.5e-19 67.9 1.2 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain polyprenyl_synt PF00348.17 CAR27677.1 - 7.8e-59 198.8 0.0 9.2e-59 198.6 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase DER1 PF04511.15 CAR27678.1 - 6e-36 124.2 7.4 6.9e-36 124.0 7.4 1.0 1 0 0 1 1 1 1 Der1-like family DUF3605 PF12239.8 CAR27679.1 - 6.6e-35 120.7 0.2 8.1e-35 120.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Myosin_head PF00063.21 CAR27680.1 - 5.3e-288 956.9 9.7 9.8e-288 956.0 9.7 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 CAR27680.1 - 5.6e-25 87.6 2.1 5.6e-25 87.6 2.1 2.4 2 0 0 2 2 2 1 DIL domain Myosin_N PF02736.19 CAR27680.1 - 0.00034 20.4 0.1 0.0011 18.7 0.1 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CAR27680.1 - 0.00051 20.3 0.1 0.0042 17.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain FPP PF05911.11 CAR27680.1 - 0.00088 17.6 23.2 0.00088 17.6 23.2 1.9 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil AAA_16 PF13191.6 CAR27680.1 - 0.055 13.9 0.2 0.28 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 CAR27680.1 - 0.15 12.6 0.0 0.15 12.6 0.0 3.2 2 1 0 2 2 2 0 ABC transporter Saccharop_dh_N PF04455.12 CAR27680.1 - 9 6.8 7.7 0.88 10.0 0.1 3.1 3 1 0 3 3 3 0 LOR/SDH bifunctional enzyme conserved region IQ PF00612.27 CAR27680.1 - 9.5 6.3 15.2 1.6 8.8 0.1 4.8 5 0 0 5 5 5 0 IQ calmodulin-binding motif Synaptobrevin PF00957.21 CAR27681.1 - 2e-31 107.6 0.2 2.3e-31 107.4 0.2 1.0 1 0 0 1 1 1 1 Synaptobrevin Phospholamban PF04272.14 CAR27681.1 - 0.039 13.4 1.3 0.061 12.8 1.3 1.3 1 0 0 1 1 1 0 Phospholamban DUF2040 PF09745.9 CAR27683.1 - 3.9e-08 33.4 10.7 9.2e-08 32.2 10.0 2.0 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) DNApol_Exo PF18136.1 CAR27684.1 - 2.8e-98 328.6 0.4 7e-98 327.2 0.0 1.9 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CAR27684.1 - 3.1e-55 187.8 0.0 3.5e-54 184.3 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase family A vATP-synt_E PF01991.18 CAR27685.1 - 2.5e-60 203.3 14.9 2.9e-60 203.1 14.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Meckelin PF09773.9 CAR27685.1 - 0.029 12.5 4.1 0.035 12.2 4.1 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Phlebovirus_NSM PF07246.11 CAR27685.1 - 0.039 13.3 12.7 0.014 14.8 9.9 1.6 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M CorA PF01544.18 CAR27686.1 - 6e-08 32.3 2.1 1.1e-07 31.5 2.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DNAJ_related PF12339.8 CAR27686.1 - 0.13 12.5 3.0 0.27 11.5 3.0 1.5 1 0 0 1 1 1 0 DNA-J related protein SKIP_SNW PF02731.15 CAR27688.1 - 2.5e-52 176.8 8.0 2.5e-52 176.8 8.0 2.6 3 0 0 3 3 3 1 SKIP/SNW domain RNase_P_Rpp14 PF01900.19 CAR27689.1 - 1.9e-34 118.0 0.1 2.4e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family DUF3808 PF10300.9 CAR27689.1 - 0.13 11.0 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) tRNA-synt_2c PF01411.19 CAR27690.1 - 2.7e-224 745.8 0.1 5.6e-224 744.7 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CAR27690.1 - 9.8e-19 67.2 0.2 2.4e-18 66.0 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CAR27690.1 - 4.1e-15 56.4 3.7 9.2e-15 55.3 3.7 1.6 1 0 0 1 1 1 1 DHHA1 domain Glyco_transf_24 PF18404.1 CAR27691.1 - 2.7e-42 145.0 2.2 5.2e-42 144.1 2.2 1.4 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CAR27691.1 - 2.1e-16 60.7 2.9 9.6e-13 48.7 0.0 4.5 4 1 1 5 5 5 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CAR27691.1 - 6.5e-11 42.3 3.2 2.6e-09 37.1 0.5 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Stealth_CR2 PF11380.8 CAR27691.1 - 0.00064 19.9 0.2 0.002 18.3 0.2 1.8 1 0 0 1 1 1 1 Stealth protein CR2, conserved region 2 Mod_r PF07200.13 CAR27691.1 - 0.015 15.4 0.0 0.043 13.9 0.0 1.8 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein UDP-g_GGTase PF06427.11 CAR27691.1 - 0.096 12.8 0.0 0.9 9.7 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose:Glycoprotein Glucosyltransferase Fungal_trans PF04082.18 CAR27692.1 - 1.4e-33 116.1 4.5 3.4e-33 114.8 1.0 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR27692.1 - 2e-08 34.2 10.7 4e-08 33.2 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIRM PF04433.17 CAR27693.1 - 2.6e-09 37.3 0.0 5.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain PBP1_TM PF14812.6 CAR27693.1 - 0.4 11.1 10.6 0.44 11.0 5.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UQ_con PF00179.26 CAR27694.1 - 1.5e-49 167.3 0.1 1.7e-49 167.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAR27694.1 - 9.7e-05 22.1 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CAR27694.1 - 0.0014 18.5 1.0 0.0024 17.7 1.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 CAR27694.1 - 0.0017 18.6 0.1 0.0029 17.9 0.1 1.5 1 1 0 1 1 1 1 RWD domain Mis12 PF05859.12 CAR27695.1 - 4.2e-40 136.9 2.4 8.7e-40 135.9 2.4 1.5 1 0 0 1 1 1 1 Mis12 protein DUF4874 PF16173.5 CAR27695.1 - 0.069 12.8 0.5 0.12 12.0 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4874) Nmad4 PF18756.1 CAR27695.1 - 0.11 12.9 0.0 0.36 11.2 0.0 1.9 1 1 0 1 1 1 0 Nucleotide modification associated domain 4 DALR_1 PF05746.15 CAR27695.1 - 0.52 10.5 3.8 0.85 9.8 0.8 2.4 1 1 1 2 2 2 0 DALR anticodon binding domain RPA43_OB PF17875.1 CAR27696.1 - 2.4e-28 99.2 0.2 7.6e-28 97.6 0.2 1.9 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 CAR27696.1 - 6.8e-11 42.4 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rpb1_5 PF04998.17 CAR27697.1 - 3.2e-95 318.6 1.8 4.1e-95 318.2 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CAR27697.1 - 1.9e-68 229.9 0.2 4.6e-68 228.6 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CAR27697.1 - 8e-40 136.3 0.5 3.2e-38 131.1 0.0 3.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CAR27697.1 - 1.9e-26 93.1 1.5 2.1e-25 89.7 0.4 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 CAR27697.1 - 1.8e-22 79.3 0.1 1.8e-22 79.3 0.1 3.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 Paf1 PF03985.13 CAR27697.1 - 0.11 11.4 19.6 0.023 13.7 15.2 1.9 2 0 0 2 2 2 0 Paf1 GTP_EFTU PF00009.27 CAR27698.1 - 9.9e-33 113.3 0.0 9.9e-33 113.3 0.0 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CAR27698.1 - 2.2e-20 72.7 0.0 8.3e-20 70.9 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CAR27698.1 - 9.2e-15 54.8 1.4 7e-10 39.2 0.1 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAR27698.1 - 6.8e-08 32.6 0.2 6e-06 26.3 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CAR27698.1 - 8.1e-05 22.5 0.1 0.00024 20.9 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 CAR27698.1 - 0.00023 21.4 0.0 0.00096 19.4 0.0 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CAR27698.1 - 0.004 16.7 0.0 0.048 13.2 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_22 PF13401.6 CAR27698.1 - 0.057 13.7 0.4 0.64 10.3 0.4 2.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 CAR27699.1 - 2.8e-38 130.2 0.0 5.9e-38 129.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CAR27699.1 - 1.6e-21 76.1 0.1 3e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CAR27699.1 - 3.7e-19 68.9 0.1 8.1e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR27699.1 - 1.7e-08 34.2 0.1 4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CAR27699.1 - 0.0036 17.4 0.5 2.1 8.4 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 CAR27699.1 - 0.012 14.6 0.2 0.028 13.4 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB HLH PF00010.26 CAR27701.1 - 1.9e-21 75.8 0.2 5.6e-21 74.2 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Med3 PF11593.8 CAR27701.1 - 0.011 14.9 5.2 0.013 14.7 5.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mif2_N PF15624.6 CAR27701.1 - 0.18 12.5 2.2 0.28 11.9 2.2 1.3 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal DUF4680 PF15730.5 CAR27701.1 - 2.2 8.6 6.2 2.8 8.3 5.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4680) IMS PF00817.20 CAR27702.1 - 2.3e-29 102.3 0.0 7.4e-29 100.7 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family BRCT_2 PF16589.5 CAR27702.1 - 9e-12 45.3 0.0 2.6e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_C PF11799.8 CAR27702.1 - 7.2e-10 39.6 0.0 2.6e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT PF00533.26 CAR27702.1 - 4.4e-06 27.0 0.1 0.00014 22.2 0.0 3.1 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain REV1_C PF16727.5 CAR27702.1 - 0.00027 21.3 0.0 0.00061 20.1 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain LIG3_BRCT PF16759.5 CAR27702.1 - 0.0028 17.9 0.0 0.0098 16.2 0.0 1.9 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 CAR27702.1 - 0.02 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain IMS_HHH PF11798.8 CAR27702.1 - 0.027 14.8 0.0 0.089 13.2 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif DUF668 PF05003.12 CAR27702.1 - 0.065 13.7 0.4 3.2 8.3 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF668) PK PF00224.21 CAR27703.1 - 1.5e-166 553.6 2.9 1.8e-166 553.2 2.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CAR27703.1 - 5.3e-34 117.0 0.1 3.1e-33 114.5 0.0 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CAR27703.1 - 3.7e-06 26.2 0.2 1e-05 24.8 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family MNE1 PF13762.6 CAR27705.1 - 8.1e-49 165.5 7.3 8.1e-49 165.5 7.3 3.6 3 1 0 3 3 3 1 Mitochondrial splicing apparatus component PPR_3 PF13812.6 CAR27705.1 - 0.014 15.5 0.5 0.06 13.4 0.1 2.3 2 0 0 2 2 2 0 Pentatricopeptide repeat domain HARP PF07443.13 CAR27705.1 - 0.094 12.4 0.6 2.5 7.8 0.1 3.1 3 0 0 3 3 3 0 HepA-related protein (HARP) MPS-4 PF17523.2 CAR27705.1 - 0.16 12.1 1.5 1 9.5 0.2 2.6 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Pkinase PF00069.25 CAR27706.1 - 7.3e-54 182.9 0.0 2.1e-53 181.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27706.1 - 1.4e-29 103.1 0.0 2.6e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CAR27706.1 - 1.6e-16 60.4 0.0 4.6e-15 55.7 0.0 2.7 2 0 0 2 2 2 1 FHA domain Pkinase_fungal PF17667.1 CAR27706.1 - 9.3e-07 28.0 1.0 1.7e-06 27.1 0.0 1.8 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 CAR27706.1 - 5.6e-05 22.6 0.0 8.1e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 CAR27706.1 - 0.0038 17.5 0.0 0.012 15.9 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 CAR27706.1 - 0.0047 16.3 0.0 0.0088 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR27706.1 - 0.14 12.0 0.0 0.55 10.1 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family TFB6 PF17110.5 CAR27707.1 - 2.8e-33 115.1 0.2 8.9e-30 103.7 0.0 2.7 2 1 1 3 3 3 2 Subunit 11 of the general transcription factor TFIIH SOG2 PF10428.9 CAR27708.1 - 2.5e-143 479.0 18.3 2.5e-143 479.0 18.3 2.6 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 CAR27708.1 - 2.1e-14 53.0 6.4 1e-07 31.6 3.2 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CAR27708.1 - 7.9e-11 42.0 11.0 3.3e-06 27.4 1.2 3.3 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CAR27708.1 - 0.0002 20.9 3.4 0.0014 18.2 1.8 2.7 2 1 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 CAR27708.1 - 0.0033 17.8 9.5 10 7.1 0.1 6.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 CAR27708.1 - 0.0086 16.1 6.6 0.48 10.6 0.1 4.2 4 0 0 4 4 4 1 Leucine Rich repeat Neur_chan_memb PF02932.16 CAR27708.1 - 0.43 10.6 14.7 7.1 6.6 0.0 3.2 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region SpecificRecomb PF10136.9 CAR27708.1 - 1.8 6.8 7.7 0.039 12.3 0.6 1.7 2 0 0 2 2 2 0 Site-specific recombinase Cyto_heme_lyase PF01265.17 CAR27709.1 - 2.9e-100 335.6 4.9 6.4e-100 334.5 4.9 1.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase PPR PF01535.20 CAR27710.1 - 0.044 14.1 0.2 67 4.1 0.0 4.1 3 1 1 4 4 4 0 PPR repeat MAS20 PF02064.15 CAR27710.1 - 0.12 12.5 0.5 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 MAS20 protein import receptor Cyclin_N PF00134.23 CAR27711.1 - 4.1e-24 84.8 1.1 8.2e-24 83.8 1.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cupin_8 PF13621.6 CAR27712.1 - 2.9e-44 151.7 0.0 4.2e-43 147.9 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CAR27712.1 - 5.5e-05 22.8 0.2 0.0092 15.5 0.0 2.7 3 0 0 3 3 3 2 Cupin superfamily protein JmjC PF02373.22 CAR27712.1 - 0.027 14.9 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase tRNA_synt_1c_R1 PF04558.15 CAR27713.1 - 0.0088 16.1 0.1 0.019 15.0 0.1 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_2c PF01411.19 CAR27713.1 - 0.073 11.6 0.1 1.5 7.2 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II (A) He_PIG_assoc PF10632.9 CAR27713.1 - 0.22 11.2 1.8 0.25 11.1 0.3 1.9 2 0 0 2 2 2 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase ETF_QO PF05187.13 CAR27714.1 - 4.9e-46 155.2 0.7 8.4e-46 154.4 0.7 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CAR27714.1 - 6.8e-11 42.3 0.2 4.1e-05 23.3 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CAR27714.1 - 8.1e-09 35.1 0.1 0.0027 16.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 CAR27714.1 - 9.5e-09 34.8 0.0 0.0011 18.2 0.1 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 CAR27714.1 - 1e-06 28.9 0.0 3.4e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CAR27714.1 - 6.1e-05 21.9 0.1 0.0013 17.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 CAR27714.1 - 8e-05 22.0 0.0 0.0029 16.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR27714.1 - 0.00058 19.2 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAR27714.1 - 0.00059 19.8 0.1 0.0012 18.9 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 CAR27714.1 - 0.0008 18.7 0.3 0.0023 17.2 0.3 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CAR27714.1 - 0.0018 18.8 0.1 4.1 8.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CAR27714.1 - 0.0027 17.1 0.0 0.9 8.8 0.0 2.3 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 CAR27714.1 - 0.0032 16.9 0.0 0.0068 15.8 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CAR27714.1 - 0.0049 15.8 0.1 0.085 11.7 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Fer4_7 PF12838.7 CAR27714.1 - 0.016 15.8 0.6 0.046 14.3 0.6 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 CAR27714.1 - 0.036 13.1 0.1 0.054 12.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_2 PF12797.7 CAR27714.1 - 0.097 12.8 0.5 0.31 11.2 0.5 1.9 1 0 0 1 1 1 0 4Fe-4S binding domain K_oxygenase PF13434.6 CAR27714.1 - 0.22 10.6 0.0 0.4 9.8 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) CDC24 PF06395.11 CAR27715.1 - 1.3e-36 124.7 0.5 3.2e-36 123.5 0.5 1.7 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 CAR27715.1 - 1.6e-31 109.1 0.1 4.3e-31 107.7 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 CAR27715.1 - 1.2e-30 107.1 3.9 1.2e-30 107.1 3.9 2.9 4 0 0 4 4 4 1 RhoGEF domain PB1 PF00564.24 CAR27715.1 - 3.7e-07 30.0 1.1 1.5e-06 28.0 0.5 2.5 2 0 0 2 2 2 1 PB1 domain PH PF00169.29 CAR27715.1 - 0.041 14.4 1.3 0.28 11.7 1.3 2.3 1 1 0 1 1 1 0 PH domain DUF615 PF04751.14 CAR27715.1 - 0.065 13.2 0.0 0.26 11.2 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Put_DNA-bind_N PF06971.13 CAR27715.1 - 0.07 13.2 0.1 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus COPIIcoated_ERV PF07970.12 CAR27716.1 - 4.6e-78 262.1 0.1 5.6e-78 261.8 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CAR27716.1 - 6.7e-30 103.3 0.5 1.5e-29 102.2 0.1 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF5408 PF17402.2 CAR27716.1 - 0.0056 16.5 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5408) PX PF00787.24 CAR27717.1 - 7.5e-22 77.4 0.0 1.1e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 PX domain Histone PF00125.24 CAR27718.1 - 7.2e-26 91.1 0.0 8.7e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CAR27718.1 - 7.5e-21 74.2 1.3 7.5e-21 74.2 1.3 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 CAR27718.1 - 0.004 17.2 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CENP-X PF09415.10 CAR27718.1 - 0.019 15.3 0.2 0.04 14.2 0.2 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X DUF3453 PF11935.8 CAR27719.1 - 4.3e-59 199.9 0.2 4.3e-59 199.9 0.2 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3453) Ipi1_N PF12333.8 CAR27719.1 - 0.0087 16.6 0.4 0.48 11.0 0.0 3.3 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Sua5_yciO_yrdC PF01300.18 CAR27719.1 - 0.15 11.5 0.0 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 Telomere recombination SAM_2 PF07647.17 CAR27720.1 - 2e-10 40.6 0.4 8.4e-10 38.6 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CAR27720.1 - 1.3e-07 31.9 0.1 2.7e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 CAR27720.1 - 0.17 12.0 0.1 0.4 10.8 0.1 1.5 1 0 0 1 1 1 0 IGR protein motif PDEase_I PF00233.19 CAR27721.1 - 4.7e-52 177.1 0.0 8.8e-52 176.2 0.0 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CAR27721.1 - 0.0017 18.6 0.1 0.0043 17.3 0.1 1.8 1 1 0 1 1 1 1 HD domain IL4_i_Ig PF18258.1 CAR27721.1 - 0.022 15.0 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain Glycos_transf_N PF04413.16 CAR27721.1 - 0.043 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) Ku_C PF03730.14 CAR27721.1 - 0.047 14.4 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Ku70/Ku80 C-terminal arm Hph PF13694.6 CAR27722.1 - 6e-15 56.0 5.7 6e-15 56.0 5.7 4.1 3 2 0 4 4 4 1 Sec63/Sec62 complex-interacting family Atg14 PF10186.9 CAR27722.1 - 0.11 11.6 5.5 0.24 10.4 5.5 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliJ PF02050.16 CAR27722.1 - 0.13 12.5 2.7 0.32 11.2 2.7 1.7 1 0 0 1 1 1 0 Flagellar FliJ protein Sec8_exocyst PF04048.14 CAR27722.1 - 1.8 8.4 9.4 0.57 10.1 1.6 2.3 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain Saw1 PF11561.8 CAR27723.1 - 5e-95 317.7 6.7 5.6e-95 317.5 6.7 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Aldedh PF00171.22 CAR27724.1 - 2.3e-15 56.1 0.2 5.9e-12 44.8 0.0 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.17 CAR27724.1 - 0.082 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) PhoLip_ATPase_C PF16212.5 CAR27725.1 - 8.5e-85 284.5 27.0 8.5e-85 284.5 27.0 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAR27725.1 - 1.3e-24 85.6 1.4 4.2e-24 84.0 1.1 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CAR27725.1 - 6.2e-11 43.0 0.2 4.5e-05 23.8 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAR27725.1 - 6.3e-09 35.8 0.0 1.8e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CAR27725.1 - 1.6e-07 31.0 0.1 4.7e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CAR27725.1 - 0.0023 17.7 0.1 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mt_ATP-synt_B PF05405.14 CAR27725.1 - 0.016 14.8 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Ribosomal_L28e PF01778.17 CAR27726.1 - 7.3e-39 133.1 3.5 7.3e-39 133.1 3.5 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CAR27726.1 - 1.3e-30 105.9 16.0 1.3e-30 105.9 16.0 2.7 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 CAR27726.1 - 0.00025 20.5 18.4 0.00031 20.2 18.4 1.2 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 CAR27726.1 - 0.022 14.5 1.7 0.022 14.5 1.7 1.6 1 1 0 1 1 1 0 Conserved carboxylase domain DUF4598 PF15370.6 CAR27726.1 - 0.24 11.9 14.4 0.58 10.6 14.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) DUF2462 PF09495.10 CAR27726.1 - 1 10.1 4.6 8.3 7.2 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2462) RasGEF PF00617.19 CAR27727.1 - 8.7e-38 130.3 1.2 8.7e-38 130.3 1.2 3.0 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 CAR27727.1 - 3.7e-12 46.4 1.3 3.7e-12 46.4 1.3 3.4 3 0 0 3 3 3 1 RasGEF N-terminal motif LDB19 PF13002.7 CAR27728.1 - 1.9e-99 331.1 0.8 2.8e-99 330.6 0.3 1.6 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 CAR27728.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain PMT PF02366.18 CAR27729.1 - 8e-93 310.5 21.8 8e-93 310.5 21.8 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CAR27729.1 - 1.8e-57 194.2 9.9 1.8e-57 194.2 9.9 2.8 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CAR27729.1 - 2.8e-22 79.4 0.0 5.6e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 MIR domain Nucleoside_tran PF01733.18 CAR27730.1 - 1.6e-58 198.5 28.3 2.8e-42 145.2 7.4 2.5 2 1 1 3 3 3 2 Nucleoside transporter NPCC PF08058.11 CAR27730.1 - 8.8 6.4 10.4 15 5.7 5.7 2.9 2 1 0 2 2 2 0 Nuclear pore complex component Exo_endo_phos PF03372.23 CAR27731.1 - 6.2e-24 84.8 0.0 2.3e-23 82.9 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 CAR27731.1 - 3.6e-14 52.3 19.4 2.8e-09 36.6 2.4 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CAR27731.1 - 1.7e-12 47.4 8.7 5.2e-08 33.1 2.3 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CAR27731.1 - 1.9 8.8 4.0 1.4 9.1 0.4 2.7 2 0 0 2 2 2 0 Leucine Rich repeat RCC1 PF00415.18 CAR27732.1 - 8.7e-06 26.3 7.3 0.0024 18.4 0.5 3.8 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAR27732.1 - 7.9e-05 22.4 13.2 0.0016 18.2 1.9 4.0 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat SNF2_N PF00176.23 CAR27733.1 - 1.1e-57 195.4 0.2 2.4e-57 194.2 0.2 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR27733.1 - 2e-20 73.2 0.5 3.9e-18 65.8 0.1 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR27733.1 - 2.7e-09 37.3 0.0 1.9e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RWD PF05773.22 CAR27733.1 - 0.0048 17.2 0.1 0.03 14.6 0.1 2.5 1 0 0 1 1 1 1 RWD domain Gal11_ABD1 PF18535.1 CAR27734.1 - 1e-40 137.7 13.0 1e-40 137.7 13.0 9.1 5 3 2 8 8 8 1 Gal11 activator-binding domain (ABD1) Med15_fungi PF05397.12 CAR27734.1 - 5.8e-32 110.3 4.2 5.8e-32 110.3 4.2 6.9 6 2 0 6 6 6 1 Mediator complex subunit 15 KIX_2 PF16987.5 CAR27734.1 - 1.8e-18 66.3 1.0 1.8e-18 66.3 1.0 4.4 4 0 0 4 4 4 1 KIX domain GSH_synth_ATP PF03917.17 CAR27735.1 - 3.2e-130 434.3 0.0 3.9e-130 434.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CAR27735.1 - 4.7e-30 104.1 0.0 9.5e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase EI24 PF07264.11 CAR27736.1 - 0.00072 19.8 5.5 0.0011 19.3 5.5 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) 2OG-FeII_Oxy_2 PF13532.6 CAR27737.1 - 1.1e-25 91.0 0.1 1.6e-25 90.5 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_ribbon_recom PF13408.6 CAR27737.1 - 0.016 15.7 4.8 0.057 13.9 4.8 2.0 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF4996 PF16387.5 CAR27737.1 - 0.086 13.3 0.1 0.87 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function YdjO PF14169.6 CAR27737.1 - 7.8 6.3 6.6 42 4.0 0.1 2.5 1 1 1 2 2 2 0 Cold-inducible protein YdjO VirB3 PF05101.13 CAR27738.1 - 8.3 6.7 9.6 16 5.8 0.2 2.7 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein EI24 PF07264.11 CAR27739.1 - 1.9e-06 28.2 15.7 2.8e-06 27.7 15.7 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Pkinase PF00069.25 CAR27740.1 - 8.5e-63 212.2 0.0 1.5e-62 211.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27740.1 - 3.8e-22 78.8 0.0 6.5e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR27740.1 - 1.3e-08 34.5 0.0 2.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAR27740.1 - 0.0028 17.0 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR27740.1 - 0.0035 17.3 0.0 0.02 14.8 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.7 CAR27740.1 - 0.028 14.7 0.0 0.41 10.9 0.0 2.5 2 0 0 2 2 2 0 PAS domain RIO1 PF01163.22 CAR27740.1 - 0.028 14.0 0.1 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CAR27740.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RP-C_C PF11800.8 CAR27741.1 - 0.039 14.0 0.4 0.059 13.5 0.4 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region TBPIP PF07106.13 CAR27741.1 - 0.065 13.2 0.0 0.56 10.2 0.1 2.3 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain HEAT PF02985.22 CAR27742.1 - 2.6e-36 120.5 19.7 0.0024 18.0 0.1 13.5 14 0 0 14 14 14 9 HEAT repeat HEAT_2 PF13646.6 CAR27742.1 - 4e-28 97.6 3.4 2.8e-09 37.2 0.0 7.5 3 3 5 8 8 8 7 HEAT repeats Cnd1 PF12717.7 CAR27742.1 - 5.2e-08 33.1 18.6 0.014 15.4 2.9 6.2 2 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CAR27742.1 - 1.1e-07 32.3 6.7 1.5 9.5 0.0 7.3 4 2 5 9 9 9 5 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CAR27742.1 - 2.7e-06 27.8 5.9 11 6.7 0.1 7.8 9 0 0 9 9 9 1 HEAT-like repeat API5 PF05918.11 CAR27742.1 - 0.0035 16.2 3.8 2.1 7.1 0.1 3.9 2 2 2 4 4 4 2 Apoptosis inhibitory protein 5 (API5) HPS3_C PF14763.6 CAR27742.1 - 0.007 15.8 0.8 0.089 12.1 0.0 3.0 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3, C-terminal RIX1 PF08167.12 CAR27742.1 - 0.053 13.3 1.6 1.1 9.0 0.2 3.1 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Tti2 PF10521.9 CAR27742.1 - 0.075 12.6 8.3 0.82 9.2 0.1 4.3 3 2 0 4 4 4 0 Tti2 family M11L PF11099.8 CAR27742.1 - 0.98 9.7 7.0 1.7 8.9 1.0 3.1 2 1 0 2 2 2 0 Apoptosis regulator M11L like HhH-GPD PF00730.25 CAR27743.1 - 1.6e-26 92.8 0.0 2.6e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CAR27743.1 - 0.0012 18.6 0.0 0.0037 17.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Exo_endo_phos PF03372.23 CAR27744.1 - 3.7e-09 36.4 0.0 0.00028 20.5 0.0 2.1 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family SNARE PF05739.19 CAR27746.1 - 3.2e-05 23.8 0.0 3.2e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 SNARE domain DUF1241 PF06840.11 CAR27746.1 - 0.005 16.5 2.4 0.029 14.0 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) YkyA PF10368.9 CAR27746.1 - 0.12 12.1 14.6 1 9.0 0.9 3.0 3 1 0 3 3 3 0 Putative cell-wall binding lipoprotein CHDCT2 PF08074.11 CAR27746.1 - 0.25 11.5 3.2 2.3 8.3 0.6 2.3 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Cortex-I_coil PF09304.10 CAR27746.1 - 0.31 11.3 13.2 0.75 10.0 0.6 3.0 2 1 0 2 2 2 0 Cortexillin I, coiled coil SLATT_5 PF18160.1 CAR27746.1 - 1.1 8.5 4.7 0.21 10.9 0.3 2.0 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 RRM_1 PF00076.22 CAR27747.1 - 1.2e-17 63.5 0.4 4.1e-14 52.1 0.0 3.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR27747.1 - 5.7e-06 26.4 0.5 0.42 10.7 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif Sds3 PF08598.11 CAR27748.1 - 1.4e-47 162.5 0.6 1.4e-47 162.5 0.6 2.4 2 1 0 2 2 2 1 Sds3-like DUF3837 PF12939.7 CAR27748.1 - 3 8.3 8.9 2.2 8.7 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) Ribosomal_S19 PF00203.21 CAR27749.1 - 7.9e-32 109.0 0.2 1.2e-31 108.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.19 CAR27750.1 - 1.9e-24 86.0 10.5 2.3e-24 85.8 10.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cys_Met_Meta_PP PF01053.20 CAR27751.1 - 4.7e-144 479.6 0.0 5.3e-144 479.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CAR27751.1 - 0.00023 19.8 0.0 0.00036 19.2 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 CAR27751.1 - 0.0017 17.6 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CAR27751.1 - 0.0078 15.2 0.7 0.013 14.5 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class-V SIL1 PF16782.5 CAR27752.1 - 2.5e-108 361.7 12.3 3e-108 361.4 12.3 1.0 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Hairpins PF04877.12 CAR27752.1 - 0.0059 16.3 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 HrpZ DUF775 PF05603.12 CAR27753.1 - 1.2e-62 211.0 0.0 1.3e-62 210.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) tRNA-synt_1c PF00749.21 CAR27754.1 - 9e-108 359.9 0.0 1.2e-107 359.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain zf-RING_2 PF13639.6 CAR27755.1 - 1.6e-09 37.9 5.9 4.5e-08 33.3 1.7 2.3 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 CAR27755.1 - 1.5e-07 31.1 1.3 1.5e-07 31.1 1.3 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CAR27755.1 - 1.4e-06 28.5 3.1 1.8e-06 28.1 0.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CAR27755.1 - 1e-05 25.4 4.3 0.00024 21.1 0.4 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CAR27755.1 - 2.9e-05 23.8 4.3 6.8e-05 22.7 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR27755.1 - 7.5e-05 22.5 5.4 0.00011 22.0 2.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR27755.1 - 0.00017 21.5 3.3 0.0019 18.1 0.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CAR27755.1 - 0.00021 21.3 1.4 0.00021 21.3 1.4 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CAR27755.1 - 0.00032 20.5 4.5 0.0015 18.3 0.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CAR27755.1 - 0.036 14.1 0.7 0.13 12.3 0.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 CAR27755.1 - 0.22 11.3 1.3 7.5 6.4 0.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_10 PF16685.5 CAR27755.1 - 1.2 9.3 4.2 0.32 11.2 0.7 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 WD40 PF00400.32 CAR27756.1 - 9.3e-16 57.9 15.1 0.0095 16.8 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat Mod_r PF07200.13 CAR27757.1 - 4e-21 75.6 12.2 4.7e-21 75.4 12.2 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Fez1 PF06818.15 CAR27757.1 - 0.0029 18.1 6.9 0.004 17.6 6.9 1.2 1 0 0 1 1 1 1 Fez1 GAS PF13851.6 CAR27757.1 - 0.0048 16.3 6.5 0.0074 15.7 6.5 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding HBM PF16591.5 CAR27757.1 - 0.0057 16.1 4.4 0.0077 15.7 4.4 1.2 1 0 0 1 1 1 1 Helical bimodular sensor domain CENP-O PF09496.10 CAR27757.1 - 0.0066 16.4 1.3 0.0078 16.2 1.3 1.2 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component CLZ PF16526.5 CAR27757.1 - 0.0073 16.6 3.9 0.0073 16.6 3.9 2.5 1 1 2 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Phage_GP20 PF06810.11 CAR27757.1 - 0.009 15.8 5.2 0.017 14.9 5.2 1.4 1 1 0 1 1 1 1 Phage minor structural protein GP20 Filament PF00038.21 CAR27757.1 - 0.015 14.9 10.1 0.029 14.0 9.6 1.8 1 1 1 2 2 2 0 Intermediate filament protein ZapB PF06005.12 CAR27757.1 - 0.015 15.7 5.0 0.015 15.7 5.0 2.7 3 0 0 3 3 3 0 Cell division protein ZapB DUF4140 PF13600.6 CAR27757.1 - 0.021 15.3 3.1 0.036 14.5 0.9 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Seryl_tRNA_N PF02403.22 CAR27757.1 - 0.024 14.9 2.4 0.038 14.2 0.5 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 CAR27757.1 - 0.025 13.5 8.9 0.046 12.6 8.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein rRNA_proc-arch PF13234.6 CAR27757.1 - 0.03 14.3 11.2 0.43 10.5 3.2 3.0 1 1 2 3 3 3 0 rRNA-processing arch domain Retrotrans_gag PF03732.17 CAR27757.1 - 0.031 14.5 5.0 0.072 13.4 0.5 2.5 1 1 1 2 2 2 0 Retrotransposon gag protein LPP PF04728.13 CAR27757.1 - 0.034 14.5 3.0 0.15 12.5 0.5 2.6 3 0 0 3 3 2 0 Lipoprotein leucine-zipper TPR_MLP1_2 PF07926.12 CAR27757.1 - 0.041 13.9 8.9 0.12 12.5 8.6 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GhoS PF11080.8 CAR27757.1 - 0.061 13.3 0.2 0.19 11.8 0.2 1.8 1 1 0 1 1 1 0 Endoribonuclease GhoS DUF4200 PF13863.6 CAR27757.1 - 0.064 13.7 9.5 0.13 12.6 8.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) FliJ PF02050.16 CAR27757.1 - 0.073 13.3 12.5 0.038 14.2 10.5 1.6 2 0 0 2 2 1 0 Flagellar FliJ protein APG6_N PF17675.1 CAR27757.1 - 0.093 13.3 13.4 0.034 14.7 11.0 1.5 2 0 0 2 2 1 0 Apg6 coiled-coil region GAIN_A PF18619.1 CAR27757.1 - 0.099 12.9 1.9 0.3 11.3 1.9 1.9 1 1 0 1 1 1 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF2407_C PF13373.6 CAR27757.1 - 0.12 12.5 1.5 0.18 11.9 1.5 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain Spc24 PF08286.11 CAR27757.1 - 0.14 12.4 6.1 0.24 11.6 6.1 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 GARP PF16731.5 CAR27757.1 - 0.15 11.8 0.6 0.28 10.8 0.6 1.4 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma DIT1_PvcA PF05141.12 CAR27757.1 - 0.16 11.4 3.1 0.17 11.3 3.1 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Syntaxin-6_N PF09177.11 CAR27757.1 - 0.19 12.3 3.7 0.32 11.6 2.0 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cep57_CLD_2 PF14197.6 CAR27757.1 - 0.22 11.6 7.9 0.2 11.8 4.5 2.6 1 1 2 3 3 2 0 Centrosome localisation domain of PPC89 Exonuc_VII_L PF02601.15 CAR27757.1 - 0.24 10.9 3.7 0.29 10.7 3.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit OmpH PF03938.14 CAR27757.1 - 0.32 11.3 8.5 0.44 10.9 8.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) WXG100 PF06013.12 CAR27757.1 - 0.34 11.2 3.6 1.9 8.7 0.6 2.7 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Csm1_N PF18504.1 CAR27757.1 - 0.46 10.8 7.0 0.24 11.7 2.9 2.4 2 0 0 2 2 2 0 Csm1 N-terminal domain H-kinase_dim PF02895.14 CAR27757.1 - 0.49 10.8 5.7 0.96 9.9 4.1 2.1 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain bZIP_1 PF00170.21 CAR27757.1 - 0.5 10.5 6.6 0.3 11.2 2.0 2.8 2 1 1 3 3 3 0 bZIP transcription factor Occludin_ELL PF07303.13 CAR27757.1 - 0.55 11.0 8.8 0.7 10.6 7.3 1.9 1 1 1 2 2 2 0 Occludin homology domain TRPM_tetra PF16519.5 CAR27757.1 - 0.96 9.6 6.2 3.5 7.8 1.7 2.5 2 0 0 2 2 2 0 Tetramerisation domain of TRPM DHR10 PF18595.1 CAR27757.1 - 1 9.4 11.9 0.82 9.7 7.1 2.4 1 1 0 2 2 2 0 Designed helical repeat protein 10 domain FapA PF03961.13 CAR27757.1 - 1.1 7.8 6.5 1.6 7.3 6.3 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A YlqD PF11068.8 CAR27757.1 - 1.3 9.4 10.8 2.6 8.4 10.1 1.8 1 1 1 2 2 2 0 YlqD protein DivIC PF04977.15 CAR27757.1 - 2.1 8.2 6.8 0.68 9.7 2.0 2.5 1 1 1 2 2 2 0 Septum formation initiator Pox_A_type_inc PF04508.12 CAR27757.1 - 7.4 6.6 10.5 9.8 6.2 0.1 3.7 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat Abhydrolase_2 PF02230.16 CAR27758.1 - 9.9e-54 182.4 0.0 1.1e-53 182.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CAR27758.1 - 1.3e-09 37.7 0.0 0.0002 20.7 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 FSH1 PF03959.13 CAR27758.1 - 5.1e-09 36.1 0.0 1.2e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 CAR27758.1 - 9.2e-06 25.5 0.1 1.6e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 CAR27758.1 - 6.7e-05 22.5 0.0 0.0005 19.7 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 CAR27758.1 - 0.0001 23.0 0.0 0.00013 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CAR27758.1 - 0.00012 21.6 0.1 0.0033 16.9 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family AXE1 PF05448.12 CAR27758.1 - 0.04 12.6 0.0 0.063 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 CAR27758.1 - 0.049 13.5 0.4 0.23 11.3 0.1 1.9 1 1 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 CAR27758.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Dopey_N PF04118.14 CAR27759.1 - 1.8e-113 378.8 1.8 2.6e-113 378.2 0.4 2.1 2 0 0 2 2 2 1 Dopey, N-terminal ENTH PF01417.20 CAR27759.1 - 0.05 13.7 0.3 0.05 13.7 0.3 2.5 2 0 0 2 2 2 0 ENTH domain MTS PF05175.14 CAR27760.1 - 7.4e-07 28.9 0.0 1.5e-06 27.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CAR27760.1 - 9.9e-05 22.2 0.0 0.00013 21.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR27760.1 - 0.00079 19.3 0.0 0.0032 17.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR27760.1 - 0.0021 18.7 0.0 0.0047 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CAR27760.1 - 0.0023 17.4 0.0 0.036 13.4 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 CAR27760.1 - 0.023 15.4 0.0 0.11 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_33 PF10017.9 CAR27760.1 - 0.044 12.9 0.0 0.092 11.9 0.0 1.5 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent ubiquitin PF00240.23 CAR27761.1 - 8.8e-23 79.9 0.6 9.7e-23 79.7 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CAR27761.1 - 1.9e-13 50.0 0.4 2.1e-13 49.9 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAR27761.1 - 0.0033 17.8 0.1 0.01 16.3 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CAR27761.1 - 0.019 14.9 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain TPR_14 PF13428.6 CAR27762.1 - 6.4e-24 82.6 2.9 0.014 16.2 0.0 10.1 5 2 7 12 12 11 5 Tetratricopeptide repeat HAT PF02184.16 CAR27762.1 - 3.5e-15 55.6 33.7 0.0032 17.4 0.5 9.6 10 0 0 10 10 10 5 HAT (Half-A-TPR) repeat Suf PF05843.14 CAR27762.1 - 3.1e-12 47.1 18.7 0.0046 17.0 0.4 6.2 3 2 4 7 7 7 5 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CAR27762.1 - 4.5e-12 46.3 0.0 0.00074 20.0 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR27762.1 - 9.6e-09 34.7 3.8 22 5.4 0.0 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 CAR27762.1 - 1.1e-08 34.9 0.7 0.0014 18.9 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAR27762.1 - 2.6e-07 31.2 0.0 5.2 7.8 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CAR27762.1 - 4.5e-05 23.3 5.0 1.9 8.9 0.0 7.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 CAR27762.1 - 0.00019 20.8 6.2 0.02 14.1 0.2 4.2 3 2 2 5 5 5 3 Tetratricopeptide repeat U3_assoc_6 PF08640.11 CAR27762.1 - 0.00019 21.4 22.2 0.03 14.4 3.3 6.6 5 2 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_7 PF13176.6 CAR27762.1 - 0.0017 18.2 0.2 57 4.1 0.1 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat SF1-HH PF16275.5 CAR27763.1 - 2.1e-40 137.6 1.6 4.6e-40 136.5 1.6 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CAR27763.1 - 2.2e-06 27.4 0.0 4.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 CAR27763.1 - 6.2e-06 26.1 3.9 0.0023 17.8 0.2 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 CAR27763.1 - 0.00011 22.2 7.7 0.00088 19.2 0.3 2.3 2 0 0 2 2 2 2 Zinc knuckle DUF1660 PF07874.11 CAR27763.1 - 0.25 11.9 0.3 0.51 10.9 0.3 1.5 1 0 0 1 1 1 0 Prophage protein (DUF1660) Prim_Zn_Ribbon PF08273.12 CAR27763.1 - 0.35 11.2 3.4 0.74 10.1 3.4 1.6 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase Lar_restr_allev PF14354.6 CAR27763.1 - 0.71 10.3 4.5 1.3 9.5 4.5 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-CCHC_4 PF14392.6 CAR27763.1 - 1.1 9.0 4.5 2.5 7.9 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-HIT PF04438.16 CAR27763.1 - 2.4 8.1 4.1 6.8 6.7 0.6 2.3 1 1 1 2 2 2 0 HIT zinc finger Lactamase_B_6 PF16661.5 CAR27764.1 - 6.8e-79 263.8 0.0 1.5e-78 262.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CAR27764.1 - 8e-29 101.0 6.3 4.9e-28 98.4 1.9 3.1 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 CAR27764.1 - 8.5e-05 22.8 0.0 0.0011 19.3 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain efThoc1 PF11957.8 CAR27766.1 - 7.3e-119 397.6 19.3 7.3e-119 397.6 19.3 2.0 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor T6PP_N PF18572.1 CAR27766.1 - 1 9.2 6.2 1.9 8.4 2.1 3.3 3 0 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Avl9 PF09794.9 CAR27767.1 - 1.1e-143 478.6 0.5 1.8e-143 477.9 0.5 1.3 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 CAR27767.1 - 5e-06 26.4 1.5 0.002 18.1 0.3 3.2 2 1 0 2 2 2 1 Stabilization of polarity axis DUF2347 PF09804.9 CAR27767.1 - 4.6e-05 23.1 11.5 0.0051 16.4 0.0 3.7 3 2 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) Afi1 PF07792.12 CAR27767.1 - 0.014 15.9 0.0 0.014 15.9 0.0 4.1 2 1 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 CAR27767.1 - 0.12 12.3 0.8 2.9 7.8 0.2 2.5 2 0 0 2 2 2 0 DENN (AEX-3) domain Rgp1 PF08737.10 CAR27768.1 - 5e-107 358.6 2.1 6.5e-107 358.3 1.5 1.5 2 0 0 2 2 2 1 Rgp1 DUF4313 PF14190.6 CAR27768.1 - 0.002 18.1 1.5 0.21 11.6 0.0 3.2 2 1 0 3 3 3 2 Domain of unknown function (DUF4313) Arrestin_C PF02752.22 CAR27768.1 - 0.014 15.8 0.8 11 6.5 0.3 3.3 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Rbsn PF11464.8 CAR27768.1 - 0.074 12.8 0.2 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 Rabenosyn Rab binding domain ABC_membrane PF00664.23 CAR27769.1 - 6.9e-92 308.0 29.1 4.8e-49 167.4 14.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAR27769.1 - 1.6e-49 167.9 0.1 7.3e-30 104.3 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CAR27769.1 - 7.1e-09 35.4 4.6 0.0047 16.4 0.3 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CAR27769.1 - 4.4e-06 26.8 0.8 0.12 12.5 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase MTABC_N PF16185.5 CAR27769.1 - 9.1e-05 22.1 4.7 0.00017 21.2 1.4 2.7 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_29 PF13555.6 CAR27769.1 - 0.00023 20.9 0.2 0.97 9.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CAR27769.1 - 0.001 19.5 0.1 1.3 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CAR27769.1 - 0.0016 18.3 1.2 0.46 10.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CAR27769.1 - 0.0018 18.2 0.1 0.82 9.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase UPF0093 PF03653.13 CAR27769.1 - 0.0055 16.9 2.8 0.0061 16.8 0.4 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0093) Dynamin_N PF00350.23 CAR27769.1 - 0.0077 16.3 2.1 0.32 11.0 0.0 3.3 3 0 0 3 3 3 1 Dynamin family AAA_22 PF13401.6 CAR27769.1 - 0.0078 16.5 1.5 6.7 7.0 0.1 3.3 3 1 0 3 3 2 2 AAA domain DUF87 PF01935.17 CAR27769.1 - 0.011 15.8 4.8 0.24 11.5 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain Roc PF08477.13 CAR27769.1 - 0.048 13.9 0.2 10 6.4 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CAR27769.1 - 0.055 12.8 0.7 1.2 8.4 0.0 2.6 2 0 0 2 2 2 0 AIG1 family TrwB_AAD_bind PF10412.9 CAR27769.1 - 0.074 11.9 0.2 0.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.6 CAR27769.1 - 0.15 11.6 0.1 8.3 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CAR27769.1 - 0.17 11.6 0.8 15 5.2 0.2 2.7 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CAR27769.1 - 4.9 6.8 12.5 1.7 8.3 0.0 3.2 4 0 0 4 4 3 0 AAA ATPase domain Pkinase PF00069.25 CAR27770.1 - 9.8e-66 221.8 0.0 1.5e-65 221.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27770.1 - 1.9e-30 106.0 0.0 2.8e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR27770.1 - 3.1e-06 26.4 0.1 4.3e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CAR27770.1 - 6.9e-05 22.3 0.2 0.00025 20.5 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR27770.1 - 0.00071 19.6 0.7 0.0022 17.9 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 CAR27770.1 - 0.028 14.1 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CAR27770.1 - 0.047 13.0 0.0 0.33 10.2 0.0 2.2 3 0 0 3 3 3 0 Kinase-like RIO1 PF01163.22 CAR27770.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Flocculin_t3 PF13928.6 CAR27771.1 - 1.2e-13 51.3 14.2 1.2e-13 51.3 14.2 4.9 4 1 1 5 5 5 1 Flocculin type 3 repeat Redoxin PF08534.10 CAR27772.1 - 8.1e-27 93.7 0.0 1e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CAR27772.1 - 8.2e-07 29.0 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family BTB_2 PF02214.22 CAR27773.1 - 1.7e-09 37.9 0.2 1.7e-05 25.1 0.2 2.9 2 1 0 2 2 2 2 BTB/POZ domain TubC_N PF18563.1 CAR27773.1 - 0.087 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 TubC N-terminal docking domain BTB PF00651.31 CAR27773.1 - 0.27 11.5 1.8 0.69 10.2 0.2 2.3 3 0 0 3 3 3 0 BTB/POZ domain DUF3760 PF12586.8 CAR27774.1 - 0.079 13.2 2.0 0.16 12.2 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) FIN1 PF17300.2 CAR27775.1 - 7.8e-79 264.6 20.2 1.4e-78 263.8 20.2 1.3 1 1 0 1 1 1 1 Filaments in between nuclei protein-1 PHM7_cyt PF14703.6 CAR27775.1 - 0.88 9.8 7.6 1.5 9.1 7.6 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter FapA PF03961.13 CAR27775.1 - 4.1 5.9 8.4 5.1 5.6 8.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A CHORD PF04968.12 CAR27776.1 - 0.0014 19.3 4.6 0.0029 18.3 4.6 1.5 1 0 0 1 1 1 1 CHORD DUF2318 PF10080.9 CAR27776.1 - 0.025 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DNA_pol_A_exo1 PF01612.20 CAR27776.1 - 0.059 13.1 0.1 0.26 11.0 0.1 2.2 1 1 0 1 1 1 0 3'-5' exonuclease DUF2650 PF10853.8 CAR27776.1 - 0.17 11.6 0.1 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) Dynamin_M PF01031.20 CAR27776.1 - 0.65 9.2 4.6 4.8 6.3 1.1 2.7 2 1 0 2 2 2 0 Dynamin central region AAA_5 PF07728.14 CAR27777.1 - 1.2e-124 410.8 1.2 1.1e-20 74.1 0.0 10.0 10 0 0 10 10 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CAR27777.1 - 1.8e-51 172.8 4.9 1.6e-19 70.1 0.0 5.4 5 0 0 5 5 4 3 Midasin AAA lid domain AAA_3 PF07726.11 CAR27777.1 - 2.4e-32 111.5 0.0 5.7e-11 42.4 0.0 7.8 8 0 0 8 8 8 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 CAR27777.1 - 6.5e-32 109.8 0.1 2.3e-30 104.8 0.0 3.6 3 0 0 3 3 2 1 Midasin AAA lid domain AAA_7 PF12775.7 CAR27777.1 - 4.9e-30 104.4 6.5 5.3e-07 29.3 0.0 7.3 7 0 0 7 7 7 5 P-loop containing dynein motor region AAA PF00004.29 CAR27777.1 - 8.2e-24 84.5 1.5 0.0039 17.6 0.0 7.9 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAR27777.1 - 3.5e-22 79.6 8.6 0.00054 20.4 0.3 8.2 7 2 0 7 7 5 5 AAA ATPase domain Dynein_heavy PF03028.15 CAR27777.1 - 3.5e-21 75.5 0.0 5.4e-06 26.5 0.0 7.6 8 0 0 8 8 5 4 Dynein heavy chain region D6 P-loop domain Sigma54_activat PF00158.26 CAR27777.1 - 1.9e-20 73.3 0.2 0.00022 21.0 0.0 6.5 7 0 0 7 7 5 4 Sigma-54 interaction domain AAA_6 PF12774.7 CAR27777.1 - 1.1e-17 64.0 0.1 0.00067 18.7 0.0 9.6 10 1 0 10 10 9 2 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 CAR27777.1 - 9.7e-16 58.0 0.0 0.16 11.7 0.0 6.7 6 0 0 6 6 6 3 AAA domain AAA_14 PF13173.6 CAR27777.1 - 1.3e-15 57.6 0.8 0.0077 16.3 0.0 8.4 8 0 0 8 8 7 2 AAA domain ABC_tran PF00005.27 CAR27777.1 - 2.1e-15 57.5 14.8 0.00013 22.5 0.3 7.7 7 0 0 7 7 6 3 ABC transporter Sigma54_activ_2 PF14532.6 CAR27777.1 - 2.3e-15 56.9 0.3 0.0013 18.8 0.0 6.3 6 0 0 6 6 5 3 Sigma-54 interaction domain AAA_18 PF13238.6 CAR27777.1 - 6.2e-15 55.9 8.0 0.17 12.4 0.0 8.9 7 1 1 8 8 7 3 AAA domain AAA_22 PF13401.6 CAR27777.1 - 9e-15 55.1 1.3 0.084 13.1 0.0 7.4 7 0 0 7 7 6 3 AAA domain T2SSE PF00437.20 CAR27777.1 - 1.5e-14 53.7 2.0 0.11 11.5 0.0 6.1 6 0 0 6 6 6 5 Type II/IV secretion system protein TsaE PF02367.17 CAR27777.1 - 2.2e-14 53.5 2.9 0.04 13.9 0.1 6.3 6 0 0 6 6 5 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 CAR27777.1 - 1.5e-11 44.5 5.6 0.097 12.6 0.3 6.5 6 0 0 6 6 6 2 RsgA GTPase RNA_helicase PF00910.22 CAR27777.1 - 2e-11 44.2 3.1 0.22 11.9 0.0 7.3 7 0 0 7 7 6 2 RNA helicase AAA_33 PF13671.6 CAR27777.1 - 2e-11 44.2 0.9 0.014 15.5 0.1 6.4 6 0 0 6 6 6 2 AAA domain AAA_25 PF13481.6 CAR27777.1 - 3.1e-10 40.0 0.9 0.11 12.1 0.0 5.1 5 0 0 5 5 4 2 AAA domain Zeta_toxin PF06414.12 CAR27777.1 - 3.5e-10 39.5 0.5 0.56 9.5 0.0 7.2 6 0 0 6 6 6 2 Zeta toxin NACHT PF05729.12 CAR27777.1 - 7.1e-10 39.0 3.0 0.19 11.7 0.1 5.5 6 0 0 6 6 4 3 NACHT domain DUF815 PF05673.13 CAR27777.1 - 5.5e-09 35.6 0.1 0.18 10.9 0.0 5.6 5 0 0 5 5 5 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 CAR27777.1 - 5.6e-09 35.7 3.4 5.3 6.4 0.0 8.4 8 1 1 9 9 9 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 CAR27777.1 - 6.8e-09 35.3 1.0 1.8 8.4 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CAR27777.1 - 7e-09 35.7 0.5 0.26 11.0 0.0 5.7 6 0 0 6 6 5 1 IstB-like ATP binding protein Rad17 PF03215.15 CAR27777.1 - 1.6e-08 34.7 4.6 0.8 9.6 0.0 6.8 6 1 0 6 6 6 1 Rad17 P-loop domain AAA_19 PF13245.6 CAR27777.1 - 2.4e-08 34.4 6.2 0.05 13.9 0.1 6.3 7 0 0 7 7 5 1 AAA domain PduV-EutP PF10662.9 CAR27777.1 - 2.6e-08 33.7 2.4 0.064 13.0 0.0 5.3 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 CAR27777.1 - 1.3e-07 31.2 0.8 1.7 8.0 0.0 5.8 6 0 0 6 6 5 2 Bacterial TniB protein RuvB_N PF05496.12 CAR27777.1 - 3.6e-07 30.1 1.2 1.5 8.5 0.0 6.0 7 0 0 7 7 5 1 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 CAR27777.1 - 8.6e-07 29.0 4.3 16 5.6 0.2 6.6 6 0 0 6 6 6 0 50S ribosome-binding GTPase MCM PF00493.23 CAR27777.1 - 1e-06 28.0 0.5 0.23 10.6 0.0 5.1 5 0 0 5 5 5 1 MCM P-loop domain SRP54 PF00448.22 CAR27777.1 - 1.1e-06 28.4 6.7 0.22 11.1 0.0 5.0 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain Roc PF08477.13 CAR27777.1 - 1.3e-06 28.6 7.7 3.9 7.7 0.0 7.6 8 0 0 8 8 8 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CAR27777.1 - 3.6e-06 27.3 6.4 5.2 7.3 0.0 6.1 5 0 0 5 5 5 0 AAA domain KAP_NTPase PF07693.14 CAR27777.1 - 1.5e-05 24.4 0.9 1.6 7.9 0.0 5.3 5 0 0 5 5 5 1 KAP family P-loop domain VWA PF00092.28 CAR27777.1 - 6.1e-05 23.3 0.3 0.00022 21.5 0.3 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_24 PF13479.6 CAR27777.1 - 6.2e-05 22.8 3.1 3.4 7.3 0.0 6.1 6 0 0 6 6 6 0 AAA domain CPT PF07931.12 CAR27777.1 - 0.00021 21.2 0.3 18 5.1 0.0 6.0 5 1 0 5 5 5 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 CAR27777.1 - 0.00043 19.8 0.4 3.2 7.1 0.0 4.5 4 0 0 4 4 4 0 PhoH-like protein ATP-synt_ab PF00006.25 CAR27777.1 - 0.00048 19.8 0.0 7.9 6.1 0.0 3.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DEAD PF00270.29 CAR27777.1 - 0.0011 18.8 0.1 9.7 5.9 0.0 5.0 5 0 0 5 5 4 0 DEAD/DEAH box helicase PIF1 PF05970.14 CAR27777.1 - 0.0012 18.0 0.6 2.2 7.4 0.0 4.5 4 0 0 4 4 4 1 PIF1-like helicase ATP_bind_1 PF03029.17 CAR27777.1 - 0.002 18.0 10.5 5.9 6.6 0.1 6.0 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 CAR27777.1 - 0.0026 17.7 7.3 2.5 8.0 0.4 5.9 6 0 0 6 6 5 1 NTPase SRPRB PF09439.10 CAR27777.1 - 0.0026 17.2 6.8 8 5.9 0.1 5.8 7 0 0 7 7 5 0 Signal recognition particle receptor beta subunit ResIII PF04851.15 CAR27777.1 - 0.0036 17.3 14.1 1.1 9.2 0.6 5.7 6 0 0 6 6 5 2 Type III restriction enzyme, res subunit dNK PF01712.19 CAR27777.1 - 0.0037 17.2 11.2 12 5.7 0.0 6.9 7 0 0 7 7 6 0 Deoxynucleoside kinase DAP3 PF10236.9 CAR27777.1 - 0.0078 15.4 7.4 1.5 7.9 0.0 4.4 5 0 0 5 5 4 1 Mitochondrial ribosomal death-associated protein 3 CbiA PF01656.23 CAR27777.1 - 0.0094 16.0 4.2 0.48 10.5 0.1 4.6 4 0 0 4 4 4 1 CobQ/CobB/MinD/ParA nucleotide binding domain TIP49 PF06068.13 CAR27777.1 - 0.01 15.1 0.2 2.8 7.0 0.0 4.0 5 0 0 5 5 5 1 TIP49 P-loop domain cobW PF02492.19 CAR27777.1 - 0.012 15.2 6.4 5.3 6.6 0.2 4.9 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 CAR27777.1 - 0.037 13.4 10.7 11 5.3 0.0 5.8 6 0 0 6 6 5 0 KaiC FtsK_SpoIIIE PF01580.18 CAR27777.1 - 0.073 12.4 0.5 8.8 5.6 0.1 3.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family MeaB PF03308.16 CAR27777.1 - 0.079 11.9 1.1 20 4.0 0.1 3.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 CAR27777.1 - 0.2 10.8 8.0 13 4.8 0.0 5.0 6 0 0 6 6 4 0 NB-ARC domain MobB PF03205.14 CAR27777.1 - 0.56 10.1 6.6 15 5.5 0.3 4.6 5 0 0 5 5 4 0 Molybdopterin guanine dinucleotide synthesis protein B tRNA_int_endo PF01974.17 CAR27778.1 - 3.7e-23 81.4 0.1 8.8e-23 80.2 0.1 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 CAR27778.1 - 0.0027 17.4 0.0 0.47 10.2 0.0 2.7 2 0 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Pox_D5 PF03288.16 CAR27778.1 - 0.027 14.9 1.3 3.4 8.2 0.1 2.7 2 0 0 2 2 2 0 Poxvirus D5 protein-like DIRP PF06584.13 CAR27778.1 - 0.094 12.9 1.3 0.18 12.0 1.3 1.4 1 0 0 1 1 1 0 DIRP OSK PF17182.4 CAR27778.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 OSK domain CDC45 PF02724.14 CAR27780.1 - 1.3e-204 681.1 2.7 2.7e-204 680.1 2.7 1.4 1 1 0 1 1 1 1 CDC45-like protein DUF4611 PF15387.6 CAR27780.1 - 0.015 15.5 10.4 0.034 14.4 10.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 CAR27780.1 - 0.017 15.5 12.3 0.04 14.3 12.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 CAR27780.1 - 0.047 13.6 5.9 0.084 12.7 5.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region BUD22 PF09073.10 CAR27780.1 - 0.08 12.3 8.1 0.12 11.8 8.1 1.1 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.11 CAR27780.1 - 0.25 9.9 3.6 0.39 9.2 3.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PGA2 PF07543.12 CAR27780.1 - 0.3 11.1 6.3 0.61 10.1 6.3 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Nop53 PF07767.11 CAR27780.1 - 0.78 9.1 11.2 1.2 8.5 11.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) TFIIF_alpha PF05793.12 CAR27780.1 - 1 7.8 11.7 1.8 7.1 11.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cnd2 PF05786.14 CAR27780.1 - 2.1 6.9 8.3 3.1 6.4 8.3 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 FAM176 PF14851.6 CAR27780.1 - 4.7 6.9 6.0 9.7 5.9 6.0 1.5 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 CAR27780.1 - 4.8 6.4 11.3 8.7 5.6 11.3 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 CAR27780.1 - 6.1 7.3 11.1 13 6.3 11.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 CAR27780.1 - 9.3 4.3 11.4 13 3.8 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family ANAPC9 PF12856.7 CAR27781.1 - 3.8e-16 59.3 0.0 6.7e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 9 CH PF00307.31 CAR27782.1 - 5.6e-79 261.4 0.1 9.5e-20 70.8 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 CAR27782.1 - 0.0015 19.0 0.9 0.0084 16.5 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CAR27782.1 - 0.016 15.1 0.0 3.4 7.8 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain adh_short PF00106.25 CAR27783.1 - 7.4e-12 45.1 0.0 3.4e-11 43.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR27783.1 - 0.011 15.3 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR27783.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 KR domain Zn_ribbon_17 PF17120.5 CAR27784.1 - 1.7e-19 69.1 15.2 4.6e-19 67.8 15.2 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CAR27784.1 - 7.7e-08 32.9 25.3 1.8e-05 25.4 0.1 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat RWD PF05773.22 CAR27784.1 - 0.00017 21.9 0.1 0.00054 20.2 0.1 1.8 1 0 0 1 1 1 1 RWD domain C1_2 PF03107.16 CAR27784.1 - 0.0067 16.7 4.0 0.016 15.6 4.0 1.6 1 0 0 1 1 1 1 C1 domain zinc_ribbon_16 PF17034.5 CAR27784.1 - 0.11 12.7 10.2 0.39 10.9 10.2 2.0 1 0 0 1 1 1 0 Zinc-ribbon like family zf-C3HC4_2 PF13923.6 CAR27784.1 - 0.47 10.3 5.7 1.2 9.1 5.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR27784.1 - 0.5 10.7 12.2 1.2 9.5 12.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3H2C3 PF17122.5 CAR27784.1 - 1.1 9.4 5.9 2.4 8.3 5.9 1.6 1 0 0 1 1 1 0 Zinc-finger EPSP_synthase PF00275.20 CAR27785.1 - 2.8e-138 461.1 0.0 3.8e-138 460.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CAR27785.1 - 1.2e-98 329.5 0.0 1.9e-98 328.8 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CAR27785.1 - 1.4e-57 195.6 0.0 2.5e-57 194.8 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CAR27785.1 - 1.8e-33 115.9 0.0 2.4e-32 112.3 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 CAR27785.1 - 1.2e-20 73.5 0.0 4.7e-20 71.6 0.0 2.1 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 CAR27785.1 - 9.6e-09 34.9 0.1 2.2e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 CAR27785.1 - 1.1e-07 32.0 0.0 3.2e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 CAR27785.1 - 3.7e-06 26.8 0.0 1.3e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.6 CAR27785.1 - 0.1 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fe-ADH PF00465.19 CAR27785.1 - 0.11 11.3 0.1 0.24 10.1 0.1 1.6 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase THF_DHG_CYH PF00763.23 CAR27785.1 - 0.12 12.6 0.0 0.41 10.9 0.0 1.9 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DHHC PF01529.20 CAR27786.1 - 1.6e-26 93.0 12.7 1.6e-26 93.0 12.7 2.5 2 2 0 2 2 2 1 DHHC palmitoyltransferase FYVE_2 PF02318.16 CAR27786.1 - 2.2 8.5 7.9 0.7 10.1 0.2 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger 7TMR-HDED PF07697.11 CAR27788.1 - 0.042 14.0 0.1 0.047 13.8 0.1 1.0 1 0 0 1 1 1 0 7TM-HD extracellular Cu PF17563.2 CAR27788.1 - 0.054 13.7 0.2 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 Cupiennin Abhydrolase_1 PF00561.20 CAR27789.1 - 1.2e-16 61.2 0.0 3e-13 50.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR27789.1 - 1.3e-10 40.9 0.0 2e-07 30.6 0.0 3.0 2 1 1 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAR27789.1 - 4.9e-10 40.4 0.0 8.3e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 CAR27789.1 - 9.4e-08 31.7 0.2 3e-06 26.7 0.5 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 CAR27789.1 - 6.9e-05 23.1 0.0 0.00038 20.6 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Esterase PF00756.20 CAR27789.1 - 0.0003 20.5 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 CAR27789.1 - 0.0033 17.0 0.0 0.0074 15.9 0.0 1.7 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Ndr PF03096.14 CAR27789.1 - 0.051 12.3 0.0 0.13 11.0 0.0 1.6 2 0 0 2 2 2 0 Ndr family Abhydrolase_5 PF12695.7 CAR27789.1 - 0.066 13.0 0.0 0.23 11.2 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 CAR27789.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Palmitoyl protein thioesterase EHN PF06441.12 CAR27789.1 - 0.084 13.3 0.2 0.21 12.0 0.2 1.6 1 0 0 1 1 1 0 Epoxide hydrolase N terminus PGAP1 PF07819.13 CAR27789.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein Fungal_trans PF04082.18 CAR27790.1 - 5.7e-38 130.5 2.9 1e-37 129.7 2.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR27790.1 - 1e-10 41.5 9.8 2e-10 40.6 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain gpW PF02831.15 CAR27790.1 - 0.023 14.6 0.3 0.087 12.7 0.0 2.1 2 0 0 2 2 2 0 gpW DUF3741 PF12552.8 CAR27790.1 - 0.3 11.1 2.7 0.29 11.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) DUF2841 PF11001.8 CAR27791.1 - 8.6e-35 119.5 0.8 1.6e-34 118.6 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2841) F-box-like PF12937.7 CAR27792.1 - 2.9e-06 27.1 0.2 5.4e-06 26.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAR27792.1 - 0.0027 17.5 0.9 0.0054 16.6 0.9 1.4 1 0 0 1 1 1 1 F-box domain HLH PF00010.26 CAR27793.1 - 0.001 18.9 0.1 0.0025 17.7 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 CAR27793.1 - 0.0022 18.1 7.2 0.0023 18.0 7.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EF-hand_6 PF13405.6 CAR27793.1 - 0.12 12.4 2.2 0.29 11.2 2.2 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 CAR27793.1 - 0.22 11.2 5.7 0.24 11.0 4.4 1.8 2 0 0 2 2 2 0 EF hand Rtt102p PF09510.10 CAR27793.1 - 2.1 8.6 7.1 6.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Rtt102p-like transcription regulator protein Pkinase PF00069.25 CAR27794.1 - 1.3e-66 224.7 1.3 1.3e-66 224.7 1.3 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27794.1 - 3e-39 134.9 0.2 3e-39 134.9 0.2 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase KA1 PF02149.19 CAR27794.1 - 2.3e-17 62.5 0.0 4.6e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CAR27794.1 - 8.4e-07 28.6 0.0 8.4e-07 28.6 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CAR27794.1 - 5.2e-05 22.7 0.1 0.00014 21.3 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR27794.1 - 0.0093 15.9 0.1 0.0093 15.9 0.1 3.2 3 1 0 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAR27794.1 - 0.015 14.1 0.0 0.015 14.1 0.0 3.3 4 0 0 4 4 4 0 Fungal protein kinase Haspin_kinase PF12330.8 CAR27794.1 - 0.026 13.5 0.1 0.026 13.5 0.1 3.2 3 0 0 3 3 3 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CAR27794.1 - 0.062 12.8 0.1 0.062 12.8 0.1 2.8 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL PHD PF00628.29 CAR27795.1 - 0.0067 16.3 0.8 0.0067 16.3 0.8 2.2 2 0 0 2 2 2 1 PHD-finger Nyv1_N PF09426.10 CAR27797.1 - 7.3e-54 181.5 0.0 1e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.21 CAR27797.1 - 7.7e-25 86.5 0.5 1.2e-24 85.9 0.5 1.2 1 0 0 1 1 1 1 Synaptobrevin DUF3484 PF11983.8 CAR27798.1 - 0.22 12.6 6.4 0.41 11.8 6.4 1.5 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Histone PF00125.24 CAR27798.1 - 0.26 11.6 0.1 0.26 11.6 0.1 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TRM PF02005.16 CAR27799.1 - 3.7e-146 487.1 0.0 4.8e-146 486.8 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 CAR27799.1 - 8.8e-05 22.3 0.1 0.00015 21.6 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 CAR27799.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) G-patch PF01585.23 CAR27801.1 - 6.9e-12 45.1 0.1 1.6e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CAR27801.1 - 1.1e-05 25.4 0.1 1.1e-05 25.4 0.1 3.9 2 1 0 2 2 1 1 G-patch domain Neur_chan_memb PF02932.16 CAR27801.1 - 0.058 13.5 13.0 0.072 13.1 13.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YL1 PF05764.13 CAR27801.1 - 0.15 12.1 42.0 0.22 11.6 42.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein SLC12 PF03522.15 CAR27801.1 - 0.45 9.5 21.9 0.55 9.2 21.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CAR27801.1 - 0.8 6.8 11.2 0.85 6.7 11.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hid1 PF12722.7 CAR27801.1 - 2.1 6.4 19.7 2.5 6.1 19.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SWIRM-assoc_2 PF16496.5 CAR27801.1 - 2.4 6.9 29.8 3.2 6.5 29.8 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CDC45 PF02724.14 CAR27801.1 - 3.1 6.0 35.3 4.2 5.5 35.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 CAR27801.1 - 4.6 5.9 18.5 5.7 5.6 18.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein XRN_M PF17846.1 CAR27801.1 - 6.4 5.6 18.4 7.3 5.4 18.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Glyco_hydro_72 PF03198.14 CAR27802.1 - 1.8e-144 480.8 11.6 2.6e-144 480.3 11.6 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CAR27802.1 - 5.7e-28 97.4 6.6 5.7e-28 97.4 6.6 2.4 2 0 0 2 2 2 1 X8 domain Cellulase PF00150.18 CAR27802.1 - 0.00021 20.8 0.7 0.0015 18.0 0.7 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glucan_synthase PF02364.15 CAR27803.1 - 0 1392.7 13.4 0 1391.5 0.1 2.3 1 1 1 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CAR27803.1 - 1.1e-48 164.8 0.1 2.6e-48 163.6 0.1 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Barstar PF01337.18 CAR27803.1 - 0.12 12.4 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 Barstar (barnase inhibitor) DUF1798 PF08807.10 CAR27803.1 - 0.13 12.4 1.0 0.33 11.1 1.0 1.6 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) Glyco_hydro_17 PF00332.18 CAR27804.1 - 3.3e-10 40.1 0.4 5.7e-10 39.3 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 SPX PF03105.19 CAR27804.1 - 0.68 9.8 10.3 0.97 9.3 10.3 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 CAR27804.1 - 4.1 5.9 6.9 4.7 5.6 6.9 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 CAR27804.1 - 5.4 5.8 7.3 6.4 5.5 7.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MA3 PF02847.17 CAR27805.1 - 1.6e-21 76.4 3.1 6.7e-21 74.4 0.1 2.9 2 1 1 3 3 3 1 MA3 domain MIF4G PF02854.19 CAR27805.1 - 7.7e-12 45.3 1.4 1.8e-11 44.1 1.4 1.6 1 0 0 1 1 1 1 MIF4G domain CTP_transf_like PF01467.26 CAR27806.1 - 1.1e-09 38.6 0.0 1.7e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like USP7_C2 PF14533.6 CAR27807.1 - 1.7e-62 210.8 2.3 4.1e-61 206.3 0.2 3.0 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 CAR27807.1 - 9.7e-46 156.3 1.1 1.7e-45 155.6 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 CAR27807.1 - 1.6e-37 129.1 1.0 3.9e-36 124.6 0.2 2.5 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 CAR27807.1 - 2.7e-21 76.5 0.0 7e-21 75.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 CAR27807.1 - 2.5e-05 24.4 0.2 0.00034 20.7 0.1 2.7 2 0 0 2 2 2 1 MATH domain UN_NPL4 PF11543.8 CAR27807.1 - 0.00016 22.1 0.0 0.059 13.9 0.0 3.0 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 rve PF00665.26 CAR27807.1 - 0.021 15.0 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RNA12 PF10443.9 CAR27808.1 - 5.2e-173 575.9 0.9 5.2e-173 575.9 0.9 2.2 2 0 0 2 2 2 1 RNA12 protein ATPase_2 PF01637.18 CAR27808.1 - 8.8e-06 25.8 1.4 3.1e-05 24.0 0.1 2.5 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 CAR27808.1 - 7.8e-05 22.4 0.0 0.0002 21.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.6 CAR27808.1 - 0.00059 19.9 0.2 0.0075 16.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF883 PF05957.13 CAR27808.1 - 0.18 12.4 0.2 5.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ABC_membrane PF00664.23 CAR27809.1 - 1.1e-44 153.2 11.3 1.3e-44 152.9 11.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CAR27809.1 - 1.1e-33 116.7 0.1 5.7e-33 114.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CAR27809.1 - 5.6e-07 29.2 0.0 0.00083 18.9 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CAR27809.1 - 0.0012 18.7 0.0 0.0039 17.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CAR27809.1 - 0.0014 18.9 0.0 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CAR27809.1 - 0.0015 18.3 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CAR27809.1 - 0.0025 18.2 0.0 0.0073 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CAR27809.1 - 0.0088 15.6 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 CAR27809.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_ATPase PF09818.9 CAR27809.1 - 0.035 12.9 0.0 2.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_30 PF13604.6 CAR27809.1 - 0.042 13.6 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CAR27809.1 - 0.078 13.4 0.0 0.56 10.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CAR27809.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 CAR27809.1 - 0.15 12.1 0.4 1.4 9.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CAR27809.1 - 0.17 11.6 0.1 0.4 10.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CAR27809.1 - 6.6 7.2 11.2 1.4 9.4 0.1 2.7 3 0 0 3 3 3 0 AAA domain GATase_6 PF13522.6 CAR27810.1 - 5.6e-13 49.2 0.0 1.3e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CAR27810.1 - 9.7e-10 38.4 0.0 2.2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 CAR27810.1 - 7.1e-09 35.4 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 CAR27810.1 - 1.2e-05 24.4 0.0 2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DLIC PF05783.11 CAR27811.1 - 0.017 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) RNase_T PF00929.24 CAR27812.1 - 3e-06 27.9 0.0 8.4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Exonuclease Rtt102p PF09510.10 CAR27813.1 - 2.9e-46 157.0 0.4 2.9e-46 157.0 0.4 2.1 2 1 0 2 2 2 1 Rtt102p-like transcription regulator protein Trypan_PARP PF05887.11 CAR27813.1 - 7.6e-05 22.7 16.4 0.00012 22.1 16.4 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Nucleo_P87 PF07267.11 CAR27813.1 - 1.4 7.7 9.3 1.5 7.6 9.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Neur_chan_memb PF02932.16 CAR27813.1 - 1.5 8.8 6.9 1.8 8.6 6.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3591 PF12157.8 CAR27814.1 - 5.1e-169 562.6 0.1 5.1e-169 562.6 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 CAR27814.1 - 3.2e-06 26.9 0.6 6.6e-06 25.9 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CAR27814.1 - 0.13 12.4 1.8 0.15 12.2 0.4 1.9 2 0 0 2 2 2 0 Zinc knuckle Csm1_N PF18504.1 CAR27814.1 - 0.47 10.8 6.5 2.3 8.6 6.5 2.2 1 0 0 1 1 1 0 Csm1 N-terminal domain Peptidase_S10 PF00450.22 CAR27816.1 - 7.5e-126 420.9 0.2 8.8e-126 420.7 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 CAR27816.1 - 3e-13 50.4 0.0 1.1e-12 48.6 0.0 2.0 2 1 0 2 2 2 1 Carboxypeptidase Y pro-peptide KCT2 PF17818.1 CAR27816.1 - 0.14 12.3 0.3 0.27 11.3 0.0 1.5 2 0 0 2 2 2 0 Keratinocyte-associated gene product Aminotran_1_2 PF00155.21 CAR27817.1 - 9.2e-60 202.7 0.0 1.1e-59 202.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2406 PF10295.9 CAR27818.1 - 1.5e-27 96.1 0.2 2.9e-27 95.1 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Efg1 PF10153.9 CAR27819.1 - 7.7e-27 93.9 13.4 5.5e-26 91.2 13.4 2.1 1 1 0 1 1 1 1 rRNA-processing protein Efg1 Exonuc_VII_L PF02601.15 CAR27819.1 - 0.16 11.5 1.7 0.19 11.3 1.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sec63 PF02889.16 CAR27820.1 - 4.6e-118 393.0 3.7 1.1e-78 263.9 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CAR27820.1 - 3.8e-49 166.8 0.8 1.4e-25 90.1 0.5 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 CAR27820.1 - 4.4e-28 98.4 0.0 2.3e-13 50.5 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAR27820.1 - 1.2e-18 67.5 0.1 8.7e-08 32.5 0.0 3.8 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CAR27820.1 - 1.9e-05 25.0 3.5 0.041 14.2 0.1 3.9 3 2 0 3 3 2 2 AAA domain AAA PF00004.29 CAR27820.1 - 2.9e-05 24.5 0.0 0.16 12.4 0.0 4.1 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 CAR27820.1 - 0.00049 19.6 0.0 0.046 13.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 CAR27820.1 - 0.0009 19.0 0.2 2.1 8.1 0.0 3.8 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_19 PF13245.6 CAR27820.1 - 0.0028 18.0 0.2 0.36 11.2 0.2 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CAR27820.1 - 0.0074 15.4 0.0 1.5 7.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Helicase_PWI PF18149.1 CAR27820.1 - 0.03 14.5 0.1 0.16 12.2 0.1 2.3 1 0 0 1 1 1 0 N-terminal helicase PWI domain AAA_16 PF13191.6 CAR27820.1 - 0.039 14.3 0.0 19 5.6 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 CAR27820.1 - 0.19 11.1 3.2 29 4.0 0.0 3.8 3 1 0 4 4 4 0 Bacterial TniB protein Dynamitin PF04912.14 CAR27821.1 - 2.8e-17 63.1 18.4 4.5e-17 62.5 18.4 1.4 1 0 0 1 1 1 1 Dynamitin AcylCoA_dehyd_C PF12186.8 CAR27821.1 - 0.9 9.7 3.5 11 6.2 0.1 3.6 3 1 1 4 4 4 0 Acyl-CoA dehydrogenase C terminal Fib_alpha PF08702.10 CAR27821.1 - 2.3 8.4 15.9 0.12 12.6 0.8 3.3 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 CAR27821.1 - 2.7 7.7 9.4 0.12 12.1 0.9 2.6 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF1664 PF07889.12 CAR27821.1 - 6.8 6.8 9.9 3.4 7.7 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Amidase PF01425.21 CAR27822.1 - 5.2e-120 401.4 0.0 6e-120 401.2 0.0 1.0 1 0 0 1 1 1 1 Amidase AAA PF00004.29 CAR27823.1 - 1.2e-49 168.1 0.0 2e-42 144.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR27823.1 - 1.7e-08 34.1 0.1 1.3e-07 31.3 0.0 2.5 3 0 0 3 3 3 1 AAA+ lid domain AAA_2 PF07724.14 CAR27823.1 - 3.9e-07 30.4 0.0 4.8e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 CAR27823.1 - 1.6e-06 28.0 0.0 2e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 CAR27823.1 - 1.8e-06 27.8 0.1 0.013 15.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 CAR27823.1 - 2.1e-06 28.2 0.2 6.6e-05 23.4 0.1 3.2 3 1 0 3 3 3 1 AAA ATPase domain ResIII PF04851.15 CAR27823.1 - 4.1e-05 23.6 0.0 0.004 17.2 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 CAR27823.1 - 0.00028 21.0 0.0 0.82 9.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 CAR27823.1 - 0.00038 20.5 0.0 0.0023 17.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CAR27823.1 - 0.002 18.7 0.0 0.094 13.3 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.6 CAR27823.1 - 0.0023 18.3 0.0 3.6 7.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CAR27823.1 - 0.0032 17.7 0.2 0.2 11.9 0.2 2.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CAR27823.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CAR27823.1 - 0.0075 15.5 0.0 0.024 13.8 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain Sigma54_activat PF00158.26 CAR27823.1 - 0.017 14.8 0.0 1.7 8.4 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.16 CAR27823.1 - 0.022 14.2 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 CAR27823.1 - 0.024 14.0 0.1 0.18 11.2 0.1 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CAR27823.1 - 0.025 14.9 0.0 0.096 13.1 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.6 CAR27823.1 - 0.03 14.5 0.0 0.088 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CAR27823.1 - 0.032 14.3 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CAR27823.1 - 0.042 12.9 0.0 0.71 8.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Bromodomain PF00439.25 CAR27823.1 - 0.046 13.8 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Bromodomain RuvB_N PF05496.12 CAR27823.1 - 0.067 12.9 0.0 0.19 11.5 0.0 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 CAR27823.1 - 0.068 13.7 0.0 0.31 11.6 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 CAR27823.1 - 0.11 12.0 0.0 0.45 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_3 PF07726.11 CAR27823.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Got1 PF04178.12 CAR27824.1 - 7.5e-13 48.9 16.1 2.3e-12 47.3 15.7 1.8 1 1 1 2 2 2 1 Got1/Sft2-like family DUF3784 PF12650.7 CAR27824.1 - 0.17 12.1 7.9 0.44 10.8 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Herpes_LMP1 PF05297.11 CAR27824.1 - 2 7.5 6.8 2.5 7.2 6.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF1129 PF06570.11 CAR27824.1 - 2.5 7.5 5.3 3.2 7.2 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PEMT PF04191.13 CAR27824.1 - 4.9 7.6 10.0 0.21 12.0 2.6 2.2 2 1 0 2 2 2 0 Phospholipid methyltransferase DnaJ_CXXCXGXG PF00684.19 CAR27825.1 - 4.3e-05 23.8 4.6 0.084 13.2 0.2 2.3 2 0 0 2 2 2 2 DnaJ central domain HypA PF01155.19 CAR27825.1 - 0.1 12.6 0.3 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GTP_cyclohydroI PF01227.22 CAR27826.1 - 9.4e-75 250.0 0.4 1.1e-74 249.7 0.4 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CAR27826.1 - 0.00032 20.8 0.0 0.00075 19.6 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein Pkinase PF00069.25 CAR27827.1 - 5.1e-50 170.3 0.2 4.6e-49 167.2 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27827.1 - 1.4e-20 73.6 0.1 4.5e-19 68.7 0.1 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR27827.1 - 0.00022 20.6 0.1 0.043 13.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CAR27827.1 - 0.0019 17.0 0.0 0.0036 16.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase PhoD PF09423.10 CAR27828.1 - 4.7e-05 22.6 0.1 0.0022 17.0 0.0 2.6 2 1 0 2 2 2 2 PhoD-like phosphatase DEAD PF00270.29 CAR27829.1 - 4.1e-46 156.9 0.6 1.2e-45 155.4 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR27829.1 - 1.8e-25 89.4 0.0 9.6e-25 87.1 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAR27829.1 - 1.4e-18 66.9 0.5 2.5e-18 66.0 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CAR27829.1 - 3.9e-06 27.0 0.0 8.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAR27829.1 - 4.9e-05 22.7 0.0 0.00016 21.0 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 CAR27829.1 - 0.0086 15.4 0.0 0.029 13.7 0.0 1.8 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.6 CAR27829.1 - 0.11 12.7 2.1 0.3 11.4 1.0 2.4 2 1 0 2 2 2 0 AAA domain tRNA-synt_1g PF09334.11 CAR27830.1 - 1.3e-155 518.0 0.6 1.7e-155 517.6 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.10 CAR27830.1 - 2.7e-45 153.8 0.6 4.8e-45 153.0 0.6 1.4 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1 PF00133.22 CAR27830.1 - 3.6e-10 38.7 0.5 7.8e-05 21.1 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) GST_N PF02798.20 CAR27830.1 - 0.067 13.5 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Say1_Mug180 PF10340.9 CAR27831.1 - 7.2e-70 235.7 0.0 8.2e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 CAR27831.1 - 2.5e-20 73.3 0.0 3.6e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Kdo PF06293.14 CAR27832.1 - 7.5e-07 28.7 0.0 1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR27832.1 - 0.0002 21.4 0.0 0.0061 16.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 CAR27832.1 - 0.037 13.4 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Aminotran_4 PF01063.19 CAR27833.1 - 2.8e-19 69.9 0.0 6.9e-19 68.6 0.0 1.6 1 1 0 1 1 1 1 Amino-transferase class IV Adaptin_N PF01602.20 CAR27834.1 - 1.9e-98 330.3 2.4 2.2e-98 330.1 2.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CAR27834.1 - 4.2e-10 39.9 0.1 2.2e-08 34.3 0.0 2.9 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAR27834.1 - 1e-07 32.2 0.1 0.00011 22.6 0.0 4.4 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.22 CAR27834.1 - 6.3e-05 22.9 3.8 2.1 8.8 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat UNC45-central PF11701.8 CAR27834.1 - 0.0015 18.5 0.2 0.025 14.6 0.0 3.0 3 1 1 4 4 4 1 Myosin-binding striated muscle assembly central TIP120 PF08623.10 CAR27834.1 - 0.036 13.8 0.2 0.091 12.5 0.2 1.6 1 0 0 1 1 1 0 TATA-binding protein interacting (TIP20) Cohesin_HEAT PF12765.7 CAR27834.1 - 0.16 12.3 1.2 1.5 9.2 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DNA_pol_phi PF04931.13 CAR27834.1 - 4 5.4 13.3 6.4 4.7 13.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi HEAT_EZ PF13513.6 CAR27835.1 - 1.7e-09 38.0 1.0 0.056 14.0 0.0 7.4 8 0 0 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.6 CAR27835.1 - 3.4e-09 36.9 2.1 0.82 10.1 0.0 7.2 4 3 5 9 9 9 3 HEAT repeats DUF3385 PF11865.8 CAR27835.1 - 8.4e-07 29.0 0.5 0.21 11.5 0.0 5.6 3 2 1 4 4 4 2 Domain of unknown function (DUF3385) HEAT PF02985.22 CAR27835.1 - 0.00016 21.6 19.0 5.5 7.5 0.2 10.2 13 0 0 13 13 13 2 HEAT repeat Vac14_Fab1_bd PF12755.7 CAR27835.1 - 0.0057 17.2 0.3 6.4 7.4 0.0 5.2 4 2 2 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 CAR27835.1 - 0.023 14.4 0.7 2.6 7.7 0.0 4.0 4 1 0 4 4 4 0 NUC173 domain MMS19_C PF12460.8 CAR27835.1 - 0.065 12.3 0.1 8.7 5.3 0.0 3.6 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Gpi16 PF04113.14 CAR27836.1 - 3.4e-185 616.7 0.0 4.5e-185 616.3 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Elong_Iki1 PF10483.9 CAR27837.1 - 9.5e-76 255.1 0.4 1.1e-75 254.9 0.4 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF5482 PF17579.2 CAR27837.1 - 0.01 15.7 0.1 0.021 14.7 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5482) Raptor_N PF14538.6 CAR27838.1 - 7.4e-67 223.9 1.3 1e-66 223.4 0.0 1.9 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CAR27838.1 - 3.2e-09 36.2 0.2 0.0018 18.4 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat WD40 PF00400.32 CAR27838.1 - 2.8e-05 24.8 2.3 0.51 11.3 0.0 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat Cnd1 PF12717.7 CAR27838.1 - 0.00028 21.0 0.5 0.01 15.9 0.4 2.6 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAR27838.1 - 0.002 18.5 0.0 0.06 13.7 0.0 2.8 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 CAR27838.1 - 0.01 16.4 0.1 9.7 6.8 0.0 3.5 3 0 0 3 3 3 0 HEAT-like repeat XPG_N PF00752.17 CAR27839.1 - 1.6e-36 124.8 0.0 4e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CAR27839.1 - 3.6e-27 94.6 0.0 2.8e-26 91.7 0.0 2.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CAR27839.1 - 0.0021 18.6 0.0 0.0021 18.6 0.0 3.0 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold Mito_carr PF00153.27 CAR27841.1 - 6.4e-59 195.9 0.2 7.5e-19 67.4 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein PsaL PF02605.15 CAR27841.1 - 0.06 13.0 0.1 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI Androgen_recep PF02166.16 CAR27842.1 - 6 5.6 8.6 11 4.7 8.6 1.3 1 0 0 1 1 1 0 Androgen receptor 6PGD PF00393.19 CAR27843.1 - 2.6e-124 414.3 0.0 3.2e-124 414.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CAR27843.1 - 8.1e-49 165.8 0.0 1.2e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CAR27843.1 - 0.045 13.8 0.1 0.16 12.0 0.0 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 CAR27843.1 - 0.2 11.9 0.0 0.79 10.0 0.0 2.0 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Erv26 PF04148.13 CAR27844.1 - 2.2e-83 279.1 2.9 2.5e-83 279.0 2.9 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF973 PF06157.11 CAR27844.1 - 0.027 13.5 2.1 0.025 13.7 1.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF973) P34-Arc PF04045.14 CAR27845.1 - 2.2e-94 315.7 0.1 2.7e-94 315.4 0.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PAT1 PF09770.9 CAR27846.1 - 5.8e-94 316.0 49.1 9.6e-89 298.8 49.1 4.1 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Spore_III_AF PF09581.10 CAR27846.1 - 1.3 9.0 5.8 4.4 7.3 5.8 1.9 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) GREB1 PF15782.5 CAR27846.1 - 2.2 5.3 11.6 3.7 4.5 11.6 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 CAR27846.1 - 4.7 7.1 58.7 2.1 8.2 56.0 1.8 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3215 PF11503.8 CAR27848.1 - 1.3e-31 108.2 0.3 1.5e-31 108.1 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) LodA_N PF17990.1 CAR27848.1 - 0.0098 15.9 0.1 0.01 15.8 0.1 1.0 1 0 0 1 1 1 1 L-Lysine epsilon oxidase N-terminal LMBR1 PF04791.16 CAR27849.1 - 3.7e-25 88.8 28.0 5.3e-25 88.3 28.0 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein Syntaxin_2 PF14523.6 CAR27849.1 - 0.28 11.6 3.3 0.55 10.6 3.3 1.5 1 0 0 1 1 1 0 Syntaxin-like protein BCDHK_Adom3 PF10436.9 CAR27850.1 - 6.1e-60 201.7 0.0 1.6e-59 200.3 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CAR27850.1 - 1.7e-09 38.2 0.0 4.6e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PQ-loop PF04193.14 CAR27851.1 - 7.3e-27 92.9 11.6 1.4e-13 50.4 2.6 3.0 3 0 0 3 3 3 2 PQ loop repeat Glucosamine_iso PF01182.20 CAR27852.1 - 7e-54 183.1 0.0 1.6e-53 181.9 0.0 1.6 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Chorismate_bind PF00425.18 CAR27853.1 - 1.8e-72 244.0 0.0 2.8e-72 243.4 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 CAR27853.1 - 9.7e-28 97.2 0.0 1.5e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 CAR27853.1 - 1.4e-15 57.8 0.0 5.3e-15 55.9 0.0 2.0 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 CAR27853.1 - 2.2e-05 24.3 0.0 5.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 ubiquitin PF00240.23 CAR27854.1 - 8.7e-09 35.0 0.2 1e-08 34.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CAR27854.1 - 0.00047 19.9 0.3 0.00052 19.8 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MeaB PF03308.16 CAR27854.1 - 0.08 11.9 0.0 0.087 11.8 0.0 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Metallophos PF00149.28 CAR27855.1 - 7.6e-33 114.7 1.6 7.6e-33 114.7 1.6 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pkinase PF00069.25 CAR27856.1 - 1.6e-62 211.3 0.0 3.7e-62 210.1 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27856.1 - 3.2e-34 118.4 0.1 8.2e-26 90.8 0.1 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CAR27856.1 - 8e-05 22.1 0.9 0.001 18.5 0.0 2.9 4 0 0 4 4 4 1 Kinase-like APH PF01636.23 CAR27856.1 - 0.15 12.0 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family SUIM_assoc PF16619.5 CAR27856.1 - 1.4 9.0 22.6 1.2 9.3 2.4 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 CAR27857.1 - 1e-62 206.6 33.2 1.4e-11 44.8 0.1 9.2 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27857.1 - 3.1e-21 75.5 7.7 9.4e-06 25.8 0.4 5.4 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR27857.1 - 1.9e-09 37.7 0.3 0.00016 21.6 0.0 3.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.12 CAR27857.1 - 1.1e-06 29.0 0.0 2.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 CAR27857.1 - 3.1e-06 26.4 0.2 0.76 8.7 0.0 4.3 3 2 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CAR27857.1 - 1.7e-05 23.7 3.2 4.2 5.9 0.5 5.0 4 2 2 6 6 6 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CAR27857.1 - 7.7e-05 21.6 0.1 0.24 10.1 0.0 3.7 3 1 1 4 4 4 1 Nup133 N terminal like Nbas_N PF15492.6 CAR27857.1 - 0.0016 17.9 1.3 0.73 9.1 0.1 3.1 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 CAR27857.1 - 0.0024 17.8 0.1 3 7.9 0.1 3.4 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 CAR27857.1 - 0.0085 14.7 0.0 0.12 10.9 0.1 2.7 3 1 0 3 3 3 1 Cytochrome D1 heme domain WD40_like PF17005.5 CAR27857.1 - 0.0089 15.4 0.0 1.8 7.8 0.0 3.3 4 0 0 4 4 4 1 WD40-like domain TFIIIC_delta PF12657.7 CAR27857.1 - 1.4 8.8 4.3 22 4.9 0.1 3.6 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Img2 PF05046.14 CAR27858.1 - 2e-20 72.8 0.2 2.8e-20 72.4 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Glyco_transf_22 PF03901.17 CAR27859.1 - 1.2e-26 93.9 14.2 1.6e-26 93.5 14.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Imm64 PF15600.6 CAR27859.1 - 0.082 12.6 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 64 cobW PF02492.19 CAR27860.1 - 1.9e-45 154.6 0.2 3.1e-45 153.9 0.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CAR27860.1 - 2.3e-07 30.6 0.0 3.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_18 PF13238.6 CAR27860.1 - 0.0018 18.8 0.0 0.0087 16.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain GTP_EFTU PF00009.27 CAR27860.1 - 0.0034 16.9 1.6 0.048 13.2 1.6 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CAR27860.1 - 0.0037 17.7 0.0 0.021 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAR27860.1 - 0.0045 16.9 1.5 0.47 10.3 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 CAR27860.1 - 0.0096 16.4 0.6 0.31 11.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CAR27860.1 - 0.015 15.0 0.4 0.043 13.6 0.2 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CAR27860.1 - 0.021 14.9 0.0 0.063 13.4 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 CAR27860.1 - 0.022 14.8 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CAR27860.1 - 0.022 14.9 0.0 0.05 13.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 CAR27860.1 - 0.023 14.7 0.0 0.088 12.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR27860.1 - 0.038 13.9 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 CAR27860.1 - 0.038 13.9 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CAR27860.1 - 0.045 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 CAR27860.1 - 0.048 13.9 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CAR27860.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.6 CAR27860.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CAR27860.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 CAR27860.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CAR27860.1 - 0.2 11.3 0.9 0.76 9.4 0.0 2.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Pro_isomerase PF00160.21 CAR27861.1 - 3.6e-27 95.6 0.1 5.8e-27 94.9 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Zn_clus PF00172.18 CAR27862.1 - 4.9e-06 26.6 3.9 1.1e-05 25.5 3.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Orbi_NS3 PF01616.16 CAR27862.1 - 0.016 14.9 0.6 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Orbivirus NS3 Lipase_3 PF01764.25 CAR27863.1 - 2e-09 37.5 0.0 3.9e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.20 CAR27863.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR27863.1 - 0.039 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAR27863.1 - 0.067 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CAR27863.1 - 0.079 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.12 CAR27863.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Phos_pyr_kin PF08543.12 CAR27864.1 - 4.3e-14 52.5 0.0 5.9e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CAR27864.1 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 CAR27864.1 - 0.031 13.8 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase Cytokin_check_N PF10407.9 CAR27864.1 - 0.097 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus WD40 PF00400.32 CAR27865.1 - 0.015 16.1 1.8 9.8 7.2 0.2 4.5 4 0 0 4 4 4 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27865.1 - 0.029 14.7 0.0 16 5.9 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2963 PF11178.8 CAR27865.1 - 0.052 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) zf-C3HC4_2 PF13923.6 CAR27866.1 - 1.1e-11 44.3 15.7 2e-11 43.5 11.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR27866.1 - 1.1e-09 38.0 11.9 1.1e-09 38.0 11.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAR27866.1 - 1e-07 31.7 12.4 1.5e-07 31.1 7.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR27866.1 - 1.2e-07 31.6 16.0 1.6e-07 31.2 11.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger SAP PF02037.27 CAR27866.1 - 6.1e-07 29.1 0.0 1.5e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 SAP domain zf-RING_5 PF14634.6 CAR27866.1 - 9.7e-07 28.6 13.3 4.8e-06 26.4 8.7 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CAR27866.1 - 4.2e-06 27.0 16.1 8.7e-06 26.0 10.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 CAR27866.1 - 8.6e-06 25.5 4.9 8.6e-06 25.5 4.9 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CAR27866.1 - 8.1e-05 22.8 4.3 8.1e-05 22.8 4.3 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CAR27866.1 - 9.8e-05 22.1 13.6 0.00034 20.4 8.3 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 CAR27866.1 - 0.00012 22.2 0.6 0.00089 19.4 0.0 2.6 3 0 0 3 3 3 1 U-box domain zf-C3HC4_4 PF15227.6 CAR27866.1 - 0.00014 21.9 10.6 0.00014 21.9 10.6 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Mob_synth_C PF06463.13 CAR27866.1 - 0.00094 19.1 1.3 0.0027 17.6 1.3 1.8 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-RING_10 PF16685.5 CAR27866.1 - 0.0019 18.3 4.5 0.0019 18.3 4.5 1.9 2 0 0 2 2 2 1 zinc RING finger of MSL2 Rad50_zn_hook PF04423.14 CAR27866.1 - 0.12 12.2 6.9 0.1 12.5 1.1 3.3 2 1 1 3 3 3 0 Rad50 zinc hook motif RecR PF02132.15 CAR27866.1 - 1.7 8.3 10.4 9 6.0 0.1 3.9 4 0 0 4 4 3 0 RecR protein zf-RING_4 PF14570.6 CAR27866.1 - 1.7 8.5 7.0 0.87 9.4 1.9 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 CAR27866.1 - 4.5 7.8 6.9 2.2 8.8 0.6 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-Nse PF11789.8 CAR27866.1 - 4.7 7.1 9.5 6.1 6.7 6.7 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Forkhead PF00250.18 CAR27867.1 - 8e-36 122.2 0.1 1.9e-35 121.0 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain SDA1 PF05285.12 CAR27867.1 - 0.0025 17.3 14.4 0.004 16.6 14.4 1.3 1 0 0 1 1 1 1 SDA1 RNA_pol_3_Rpc31 PF11705.8 CAR27867.1 - 0.011 16.1 19.6 0.025 14.8 19.6 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.14 CAR27867.1 - 0.028 14.2 8.8 0.051 13.4 8.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.12 CAR27867.1 - 0.036 12.3 16.7 0.046 11.9 16.7 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 CAR27867.1 - 0.075 12.8 16.1 0.13 11.9 16.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mpp10 PF04006.12 CAR27867.1 - 0.18 10.2 19.2 0.24 9.8 19.2 1.1 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 CAR27867.1 - 0.26 10.6 14.7 0.39 10.0 14.7 1.3 1 0 0 1 1 1 0 BUD22 FAM176 PF14851.6 CAR27867.1 - 0.3 10.7 9.3 0.93 9.2 9.3 1.9 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 CAR27867.1 - 0.62 9.3 18.3 1.1 8.5 18.3 1.4 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 CAR27867.1 - 0.83 9.5 15.9 1.4 8.8 15.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region eIF-3c_N PF05470.12 CAR27867.1 - 1.1 7.5 4.7 1.4 7.1 4.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PI3K_1B_p101 PF10486.9 CAR27867.1 - 1.1 6.9 3.9 1.4 6.6 3.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RXT2_N PF08595.11 CAR27867.1 - 1.3 9.0 11.6 2.9 7.9 11.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal FYDLN_acid PF09538.10 CAR27867.1 - 1.5 9.5 19.5 3.9 8.2 19.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) PTPRCAP PF15713.5 CAR27867.1 - 1.5 9.1 15.2 4.5 7.6 15.2 1.8 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated CDC45 PF02724.14 CAR27867.1 - 1.6 7.0 14.9 2.2 6.5 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 CAR27867.1 - 1.7 8.0 16.8 2.6 7.4 16.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.13 CAR27867.1 - 1.7 7.5 15.5 2.5 7.0 15.5 1.2 1 0 0 1 1 1 0 Paf1 RPN2_C PF18004.1 CAR27867.1 - 3.7 7.4 6.6 6.3 6.7 6.6 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DNA_pol_phi PF04931.13 CAR27867.1 - 4.7 5.2 29.6 7.8 4.5 29.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC27 PF09507.10 CAR27867.1 - 5.2 6.3 13.4 8.2 5.7 13.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFB6 PF17110.5 CAR27867.1 - 6.3 6.5 8.9 12 5.6 8.9 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH G10 PF01125.17 CAR27868.1 - 1.6e-57 193.4 4.6 1.8e-57 193.3 4.6 1.0 1 0 0 1 1 1 1 G10 protein DNase_II PF03265.15 CAR27868.1 - 0.023 14.0 1.8 0.023 14.0 1.3 1.3 1 1 0 1 1 1 0 Deoxyribonuclease II Ytp1 PF10355.9 CAR27869.1 - 1.2e-109 365.9 6.9 1.6e-109 365.4 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CAR27869.1 - 1.7e-32 111.3 6.6 4.9e-32 109.9 6.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) UPF0029 PF01205.19 CAR27870.1 - 2.7e-28 98.3 0.0 4.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CAR27870.1 - 3.1e-07 30.7 0.0 1.8e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 RWD domain DinI PF06183.13 CAR27870.1 - 0.14 12.5 0.0 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 DinI-like family MPP6 PF10175.9 CAR27871.1 - 7.6e-06 26.5 6.6 2.2e-05 24.9 6.6 1.7 1 1 0 1 1 1 1 M-phase phosphoprotein 6 WD40 PF00400.32 CAR27872.1 - 1.5e-38 130.1 20.5 1.9e-07 31.6 0.1 11.9 13 0 0 13 13 13 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27872.1 - 1.3e-26 92.8 0.1 0.0059 16.9 0.0 9.2 5 3 5 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CAR27872.1 - 2.2e-24 85.8 0.0 4.2e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 CAR27872.1 - 5.5e-08 32.1 1.6 0.083 11.8 0.0 6.2 4 3 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CAR27872.1 - 1.2e-06 28.5 2.9 0.024 14.5 0.0 6.0 5 1 3 8 8 8 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 CAR27872.1 - 8.9e-06 25.2 0.4 4.2 6.6 0.0 4.6 3 1 1 4 4 4 3 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 CAR27872.1 - 2.8e-05 23.6 1.7 0.68 9.2 0.0 4.9 4 2 2 6 6 6 1 WD40-like domain Nup160 PF11715.8 CAR27872.1 - 0.00084 18.1 0.7 3.2 6.3 0.0 3.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_3 PF15911.5 CAR27872.1 - 0.0061 16.5 0.1 0.028 14.4 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 CAR27872.1 - 0.011 14.3 1.3 0.73 8.3 0.1 3.6 3 1 0 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.12 CAR27872.1 - 0.059 13.3 2.9 4 7.5 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nop25 PF09805.9 CAR27872.1 - 0.15 12.5 5.2 0.35 11.3 5.2 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) NOA36 PF06524.12 CAR27872.1 - 4.3 6.6 5.9 8.7 5.6 5.9 1.4 1 0 0 1 1 1 0 NOA36 protein Atx10homo_assoc PF09759.9 CAR27873.1 - 7e-37 125.4 7.5 2.6e-36 123.6 0.2 3.7 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Ribosomal_L21e PF01157.18 CAR27873.1 - 0.017 15.0 0.0 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L21e Thr_synth_N PF14821.6 CAR27874.1 - 1.3e-28 99.1 0.0 4.2e-28 97.4 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 CAR27874.1 - 1e-10 41.6 0.0 4.1e-10 39.6 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SWIB PF02201.18 CAR27875.1 - 0.00039 20.3 0.1 0.0027 17.6 0.0 2.3 2 1 0 2 2 2 1 SWIB/MDM2 domain DASH_Dad2 PF08654.10 CAR27875.1 - 0.16 12.4 0.9 0.61 10.5 0.9 2.1 1 0 0 1 1 1 0 DASH complex subunit Dad2 Ribosomal_L9_N PF01281.19 CAR27876.1 - 0.00046 19.7 0.1 0.00071 19.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain CPP1-like PF11833.8 CAR27876.1 - 0.5 10.0 2.0 0.73 9.5 2.0 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF1682 PF07946.14 CAR27877.1 - 9.4e-71 238.6 5.9 1.1e-70 238.4 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) RSS_P20 PF11757.8 CAR27877.1 - 0.051 14.0 3.4 0.31 11.5 0.5 2.6 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Ank_5 PF13857.6 CAR27878.1 - 1.8e-19 69.5 0.0 3.8e-13 49.4 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR27878.1 - 2.7e-15 56.7 0.1 6.6e-11 42.7 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAR27878.1 - 3.3e-11 43.5 0.0 1.1e-05 25.9 0.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CAR27878.1 - 5e-09 35.7 0.0 0.00044 20.5 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CAR27878.1 - 7.2e-08 32.6 0.0 0.0068 16.8 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Peptidase_M76 PF09768.9 CAR27879.1 - 6.1e-73 244.2 0.3 7.8e-73 243.9 0.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 CAR27879.1 - 0.071 13.0 0.7 0.17 11.8 0.7 1.8 1 1 0 1 1 1 0 SprT-like family MBOAT PF03062.19 CAR27880.1 - 9.5e-70 235.7 38.2 1.1e-69 235.4 38.2 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CAR27880.1 - 0.00043 20.5 4.3 0.00043 20.5 4.3 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family WBS_methylT PF12589.8 CAR27881.1 - 2.4e-14 53.8 6.4 5e-14 52.8 6.4 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 CAR27881.1 - 1.7e-11 44.6 0.0 3.4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR27881.1 - 1.4e-10 41.7 0.0 3.3e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR27881.1 - 3.2e-05 24.6 0.1 0.00016 22.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CAR27881.1 - 4.3e-05 23.0 0.1 0.00017 21.0 0.0 1.9 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CAR27881.1 - 0.00016 21.6 0.0 0.00031 20.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CAR27881.1 - 0.00028 20.5 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 CAR27881.1 - 0.00052 19.8 0.0 0.002 17.9 0.0 1.9 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CAR27881.1 - 0.00072 19.4 0.0 0.0019 18.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CAR27881.1 - 0.014 15.4 0.2 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.13 CAR27881.1 - 0.021 14.2 0.5 0.054 12.9 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ribosomal_L19 PF01245.20 CAR27882.1 - 1.7e-10 40.8 0.4 2.6e-10 40.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 NPCBM_assoc PF10633.9 CAR27882.1 - 0.084 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase HIG_1_N PF04588.13 CAR27883.1 - 4.2e-05 23.7 0.4 9.3e-05 22.6 0.4 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Peptidase_S8 PF00082.22 CAR27884.1 - 6.3e-30 104.5 2.5 2.3e-29 102.6 2.5 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CAR27884.1 - 0.0045 17.6 0.0 0.0097 16.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 KH_dom-like PF14714.6 CAR27884.1 - 0.03 14.6 0.4 0.55 10.6 0.3 2.3 2 0 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Tim17 PF02466.19 CAR27885.1 - 3e-28 98.4 4.4 4e-28 98.0 4.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.9 CAR27885.1 - 0.19 11.9 8.5 1.9 8.7 2.6 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF4611 PF15387.6 CAR27887.1 - 0.025 14.8 2.9 0.036 14.3 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 CAR27887.1 - 0.1 11.9 1.8 0.11 11.8 1.8 1.0 1 0 0 1 1 1 0 NOA36 protein ACC_central PF08326.12 CAR27888.1 - 1e-260 867.0 0.0 1.6e-260 866.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CAR27888.1 - 5.2e-184 612.5 0.0 6.9e-184 612.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CAR27888.1 - 2.4e-50 171.0 0.1 6.1e-50 169.6 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CAR27888.1 - 1.6e-29 102.7 0.1 3.7e-29 101.5 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CAR27888.1 - 1.2e-20 73.6 0.0 6.3e-20 71.3 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CAR27888.1 - 6e-18 64.4 0.2 1.5e-17 63.2 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CAR27888.1 - 0.0046 16.5 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CAR27888.1 - 0.0052 16.9 0.0 0.045 13.8 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CAR27888.1 - 0.05 13.4 0.4 9.8 6.1 0.1 2.6 1 1 1 2 2 2 0 Biotin-lipoyl like ATPgrasp_Ter PF15632.6 CAR27888.1 - 0.052 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon GxGYxYP_N PF16216.5 CAR27888.1 - 0.17 12.0 0.0 0.56 10.3 0.0 1.8 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Dus PF01207.17 CAR27889.1 - 7.3e-53 179.7 0.0 2.6e-52 177.9 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF1708 PF08101.11 CAR27890.1 - 1.7e-57 195.5 1.0 1.7e-57 195.5 1.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) DUF4667 PF15700.5 CAR27891.1 - 6.6e-11 42.8 4.6 6.6e-11 42.8 4.6 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4667) SPX PF03105.19 CAR27892.1 - 2.8e-43 149.3 8.0 1.7e-27 97.4 0.2 2.5 2 1 1 3 3 3 2 SPX domain CitMHS PF03600.16 CAR27892.1 - 3.3e-23 82.3 72.2 7.9e-22 77.8 40.5 2.2 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 CAR27892.1 - 1.6e-22 80.2 42.4 2.2e-22 79.7 42.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region PRK PF00485.18 CAR27893.1 - 2.6e-65 219.9 0.0 3.7e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 CAR27893.1 - 1e-30 106.7 0.2 2.1e-30 105.7 0.2 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 CAR27893.1 - 0.00011 22.8 0.0 0.00044 20.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR27893.1 - 0.00055 20.1 0.0 0.0022 18.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CAR27893.1 - 0.0013 19.1 0.3 0.052 14.0 0.3 2.6 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 CAR27893.1 - 0.0014 18.4 0.3 0.16 11.7 0.0 2.5 3 0 0 3 3 3 1 Cytidylate kinase Zeta_toxin PF06414.12 CAR27893.1 - 0.0093 15.3 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.12 CAR27893.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA PF00004.29 CAR27893.1 - 0.06 13.8 0.0 0.38 11.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CAR27893.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CAR27893.1 - 0.17 12.3 0.0 0.8 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain CbiA PF01656.23 CAR27893.1 - 0.26 11.3 0.6 0.95 9.5 0.6 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain HA2 PF04408.23 CAR27894.1 - 3.3e-18 65.9 0.2 9.5e-18 64.5 0.0 1.9 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CAR27894.1 - 1.1e-15 57.8 0.0 2.7e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAR27894.1 - 3e-12 46.9 0.0 1.1e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAR27894.1 - 2.7e-07 30.5 0.2 6.7e-07 29.2 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR27894.1 - 6.5e-05 23.2 1.5 9.7e-05 22.7 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAR27894.1 - 0.00017 21.4 0.1 0.00029 20.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CAR27894.1 - 0.0012 18.0 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 CAR27894.1 - 0.0027 18.0 0.3 0.0078 16.6 0.3 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CAR27894.1 - 0.019 15.5 1.8 0.077 13.5 0.0 2.9 3 1 0 3 3 3 0 ABC transporter PhoH PF02562.16 CAR27894.1 - 0.021 14.3 0.0 0.056 12.9 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 CAR27894.1 - 0.023 14.7 0.1 0.046 13.7 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain NB-ARC PF00931.22 CAR27894.1 - 0.04 13.1 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 CAR27894.1 - 0.078 13.0 0.5 2.1 8.4 0.5 2.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CAR27894.1 - 0.12 12.8 0.2 0.41 11.0 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 CAR27894.1 - 0.14 12.1 5.8 2 8.4 0.7 3.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Glyoxalase PF00903.25 CAR27895.1 - 4.6e-35 120.6 0.1 1.6e-18 67.2 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CAR27895.1 - 4.2e-11 43.1 0.0 6.9e-05 23.1 0.0 3.7 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 CAR27895.1 - 2.7e-05 24.9 0.0 0.12 13.2 0.0 2.7 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 CAR27895.1 - 0.00011 22.1 0.3 0.52 10.3 0.0 4.1 3 1 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 CAR27895.1 - 0.0042 17.2 0.0 0.72 9.9 0.0 3.1 2 2 0 2 2 2 1 Glyoxalase-like domain CppA_N PF14506.6 CAR27895.1 - 0.078 13.0 0.1 5 7.2 0.0 2.7 3 0 0 3 3 3 0 CppA N-terminal PH_15 PF17339.2 CAR27895.1 - 0.18 11.7 0.5 1.4 8.9 0.3 2.2 2 0 0 2 2 2 0 PH domain AA_permease PF00324.21 CAR27896.1 - 2e-81 274.0 40.1 2.7e-81 273.6 40.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR27896.1 - 7.5e-25 87.6 42.3 1.4e-24 86.8 42.3 1.4 1 0 0 1 1 1 1 Amino acid permease Peptidase_M19 PF01244.21 CAR27897.1 - 2.5e-102 342.3 0.0 2.9e-102 342.1 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) PFK PF00365.20 CAR27898.1 - 4.6e-185 613.5 3.4 2.4e-104 348.7 1.4 2.2 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 CAR27898.1 - 0.11 12.1 1.1 0.35 10.5 0.3 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Inp1 PF12634.7 CAR27899.1 - 9.3e-28 97.0 0.0 1.1e-25 90.3 0.0 2.6 1 1 1 2 2 2 2 Inheritance of peroxisomes protein 1 CDC45 PF02724.14 CAR27899.1 - 0.2 9.9 7.1 0.26 9.5 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4005 PF13178.6 CAR27899.1 - 9.7 6.9 8.4 1.9 9.2 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4005) bZIP_2 PF07716.15 CAR27900.1 - 3.1e-11 43.2 15.9 5.6e-11 42.4 15.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CAR27900.1 - 3.9e-09 36.5 15.5 7.1e-09 35.6 15.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor Uds1 PF15456.6 CAR27900.1 - 0.0047 17.1 2.9 0.0068 16.6 2.9 1.2 1 0 0 1 1 1 1 Up-regulated During Septation TonB_N PF16031.5 CAR27900.1 - 0.0052 17.3 2.8 0.0083 16.6 2.8 1.3 1 0 0 1 1 1 1 TonB polyproline region DivIC PF04977.15 CAR27900.1 - 0.029 14.2 4.0 0.053 13.3 4.0 1.4 1 0 0 1 1 1 0 Septum formation initiator Mod_r PF07200.13 CAR27900.1 - 0.04 14.0 4.1 0.062 13.4 4.1 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein NRBF2 PF08961.10 CAR27900.1 - 0.14 11.8 3.4 0.36 10.4 3.4 1.7 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator FAM76 PF16046.5 CAR27900.1 - 0.17 11.2 1.4 0.21 10.9 1.4 1.1 1 0 0 1 1 1 0 FAM76 protein YabA PF06156.13 CAR27900.1 - 0.19 12.4 2.6 0.28 11.9 2.6 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF4349 PF14257.6 CAR27900.1 - 7.9 5.9 7.9 12 5.2 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Gti1_Pac2 PF09729.9 CAR27901.1 - 1.4e-53 181.7 0.5 2.1e-52 177.9 0.0 2.1 2 0 0 2 2 2 1 Gti1/Pac2 family TPPII_N PF12583.8 CAR27901.1 - 0.19 12.3 0.3 0.19 12.3 0.3 2.8 3 0 0 3 3 3 0 Tripeptidyl peptidase II N terminal Mito_carr PF00153.27 CAR27902.1 - 4.4e-74 244.5 1.1 8.3e-27 93.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CAR27902.1 - 0.013 14.7 0.2 4.1 6.5 0.0 3.2 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Thioredoxin PF00085.20 CAR27903.1 - 1.6e-23 82.7 0.3 8.2e-18 64.3 0.0 4.4 3 1 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 CAR27903.1 - 7.5e-08 32.5 0.5 0.0031 17.5 0.0 3.5 2 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_4 PF13462.6 CAR27903.1 - 0.0014 18.8 1.9 0.02 15.0 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 CAR27903.1 - 0.0022 18.3 0.5 0.015 15.6 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like OST3_OST6 PF04756.13 CAR27903.1 - 0.0064 15.9 0.3 0.34 10.2 0.0 3.2 3 1 0 3 3 3 1 OST3 / OST6 family, transporter family Forkhead PF00250.18 CAR27903.1 - 0.017 15.4 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Forkhead domain DUF2205 PF10224.9 CAR27903.1 - 0.21 11.6 1.0 0.73 9.9 1.0 1.9 1 0 0 1 1 1 0 Short coiled-coil protein Use1 PF09753.9 CAR27904.1 - 1.6e-06 28.1 0.1 1.9e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 ParA PF10609.9 CAR27905.1 - 2.3e-96 322.0 0.0 2.7e-96 321.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CAR27905.1 - 3.2e-10 40.2 0.0 7.1e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CAR27905.1 - 2.6e-07 30.7 0.0 0.00058 19.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain MipZ PF09140.11 CAR27905.1 - 1.1e-05 24.9 0.0 4.7e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CAR27905.1 - 2.5e-05 23.6 0.1 0.00016 20.9 0.1 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 CAR27905.1 - 0.0063 16.0 0.0 0.019 14.5 0.0 1.7 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 CAR27905.1 - 0.0069 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CAR27905.1 - 0.013 15.1 0.1 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 CAR27905.1 - 0.025 14.0 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family IstB_IS21 PF01695.17 CAR27905.1 - 0.13 12.0 0.1 0.96 9.2 0.1 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein NB-ARC PF00931.22 CAR27905.1 - 0.15 11.2 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 CAR27905.1 - 0.17 12.3 0.1 0.92 9.9 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain Pap_E4 PF02711.14 CAR27906.1 - 0.093 13.7 6.3 0.19 12.7 6.3 1.5 1 0 0 1 1 1 0 E4 protein Prefoldin_2 PF01920.20 CAR27907.1 - 7.5e-20 70.9 6.8 8.3e-20 70.7 6.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit BLOC1_2 PF10046.9 CAR27907.1 - 0.0055 17.0 5.6 0.16 12.3 1.2 2.1 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 CAR27907.1 - 0.088 13.3 5.6 0.57 10.7 5.6 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 CAR27907.1 - 0.6 10.8 3.3 7.7 7.2 0.7 2.1 2 0 0 2 2 2 0 SlyX DDOST_48kD PF03345.14 CAR27908.1 - 4.7e-125 417.7 0.3 5.7e-125 417.4 0.3 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Syja_N PF02383.18 CAR27910.1 - 1.4e-50 172.4 0.2 2.4e-50 171.7 0.2 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CAR27910.1 - 1.1e-11 44.7 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BTB PF00651.31 CAR27911.1 - 4.7e-17 62.2 0.9 1.2e-14 54.5 0.4 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.7 CAR27911.1 - 1.3e-06 28.9 0.0 8.1e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAR27911.1 - 5.9e-06 26.7 0.1 2.7e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAR27911.1 - 0.00042 20.6 0.0 0.0013 19.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CAR27911.1 - 0.00051 20.4 0.3 0.0086 16.5 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 CAR27911.1 - 0.00095 19.5 0.1 0.041 14.4 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.8 CAR27911.1 - 0.0026 17.9 0.3 0.0084 16.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) RRM_1 PF00076.22 CAR27913.1 - 1.3e-19 69.8 0.0 2.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR27913.1 - 0.00067 19.5 0.0 0.0023 17.8 0.0 1.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CAR27913.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CAR27913.1 - 0.034 13.7 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop16 PF09420.10 CAR27914.1 - 3.8e-68 229.7 23.6 1.2e-67 228.0 23.6 1.6 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 PMI_typeI PF01238.21 CAR27915.1 - 2.3e-151 504.2 0.0 2.7e-151 504.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 CAR27915.1 - 4e-05 23.5 0.0 0.0026 17.7 0.0 2.6 3 0 0 3 3 3 1 AraC-like ligand binding domain Cupin_2 PF07883.11 CAR27915.1 - 0.0014 18.3 0.0 0.87 9.4 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding_2 PF14525.6 CAR27915.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AraC-binding-like domain HIM1 PF08732.10 CAR27916.1 - 4.4e-13 49.1 0.0 1.9e-10 40.5 0.0 2.2 1 1 1 2 2 2 2 HIM1 Epimerase PF01370.21 CAR27916.1 - 1.3e-06 28.0 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CAR27916.1 - 1e-05 25.2 0.0 0.0001 22.0 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CAR27916.1 - 1.9e-05 24.7 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDA1_CD39 PF01150.17 CAR27917.1 - 1.4e-146 488.5 0.0 1.9e-146 488.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CAR27917.1 - 0.0077 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GN3L_Grn1 PF08701.11 CAR27918.1 - 5.7e-24 84.0 15.7 1.9e-23 82.3 15.7 1.9 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 CAR27918.1 - 1e-17 64.3 0.1 1.2e-13 51.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR27918.1 - 4.8e-07 29.4 0.1 2.3e-06 27.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAR27918.1 - 1.1e-05 25.4 0.1 0.00046 20.1 0.1 2.4 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 CAR27918.1 - 0.00021 21.4 5.4 0.071 13.2 0.1 3.7 2 2 0 3 3 3 2 Dynamin family AIG1 PF04548.16 CAR27918.1 - 0.00021 20.7 0.0 0.00062 19.2 0.0 1.8 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 CAR27918.1 - 0.00043 19.9 0.0 0.1 12.1 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 CAR27918.1 - 0.0011 19.5 0.2 0.0074 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CAR27918.1 - 0.0081 15.8 0.1 4.9 6.7 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 CAR27918.1 - 0.0099 14.9 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 CAR27918.1 - 0.092 13.0 0.0 3.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CNDH2_C PF16858.5 CAR27918.1 - 1.2 9.0 12.0 2 8.2 12.0 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term LRR_4 PF12799.7 CAR27919.1 - 3.3e-15 55.9 23.6 0.0031 17.9 1.4 5.9 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) CAP_GLY PF01302.25 CAR27919.1 - 1.5e-14 53.8 0.2 2.8e-14 52.9 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 CAR27919.1 - 3.2e-06 26.8 22.1 0.0046 16.7 6.7 5.2 1 1 5 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 CAR27919.1 - 4.6e-06 26.2 1.4 0.0006 19.4 0.2 2.6 2 0 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 CAR27919.1 - 0.056 13.5 18.1 4.8 7.5 0.7 6.0 6 0 0 6 6 6 0 Leucine Rich repeat UN_NPL4 PF11543.8 CAR27919.1 - 0.11 13.0 0.2 0.28 11.7 0.2 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Pre-PUA PF17832.1 CAR27920.1 - 1.9e-26 92.6 1.2 3.9e-26 91.5 1.2 1.5 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 CAR27920.1 - 6.9e-22 77.2 0.0 9.9e-22 76.7 0.0 1.2 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CAR27920.1 - 0.00046 20.4 2.2 0.00063 20.0 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) NCA2 PF08637.10 CAR27922.1 - 7.2e-96 320.8 2.6 7.2e-96 320.8 2.6 1.4 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 SH3_1 PF00018.28 CAR27923.1 - 8.3e-14 50.9 0.0 1.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR27923.1 - 7.2e-13 48.2 0.0 1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR27923.1 - 6.2e-10 38.6 0.0 8.7e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 CAR27923.1 - 0.021 14.9 7.4 0.024 14.7 7.4 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) G_path_suppress PF15991.5 CAR27923.1 - 0.23 11.5 4.7 0.28 11.3 4.7 1.1 1 0 0 1 1 1 0 G-protein pathway suppressor CYYR1 PF10873.8 CAR27923.1 - 6.3 7.2 9.1 9.7 6.6 9.1 1.2 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Tmemb_170 PF10190.9 CAR27924.1 - 1.1e-13 51.4 10.8 1.3e-13 51.2 10.8 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF1129 PF06570.11 CAR27924.1 - 0.25 10.8 1.2 0.32 10.5 0.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Proteasome PF00227.26 CAR27925.1 - 2.8e-57 193.3 0.8 3.5e-57 193.0 0.8 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR27925.1 - 4.9e-13 48.5 2.1 8.2e-12 44.6 0.2 3.1 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature DUF4823 PF16105.5 CAR27925.1 - 0.066 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4823) WW PF00397.26 CAR27926.1 - 2.4e-17 62.7 7.1 1.4e-09 37.9 3.0 2.6 2 0 0 2 2 2 2 WW domain FF PF01846.19 CAR27926.1 - 2.4e-06 27.6 2.1 2.4e-06 27.6 2.1 3.4 4 0 0 4 4 4 1 FF domain WW_1 PF18507.1 CAR27926.1 - 0.066 12.9 0.3 13 5.6 0.1 2.5 2 0 0 2 2 2 0 WW domain Spectrin_like PF18373.1 CAR27927.1 - 0.0059 16.6 1.0 0.02 15.0 1.0 1.8 1 0 0 1 1 1 1 Spectrin like domain Pet20 PF08692.10 CAR27928.1 - 9.6e-47 158.9 0.0 1.2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet20 Ribonuc_L-PSP PF01042.21 CAR27929.1 - 1.4e-22 80.0 0.0 1.7e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP RPN1_RPN2_N PF17781.1 CAR27929.1 - 0.036 13.5 0.0 0.044 13.2 0.0 1.1 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain UQ_con PF00179.26 CAR27930.1 - 1.4e-40 138.2 0.0 1.6e-40 138.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 CAR27930.1 - 4.5e-05 23.1 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 CAR27930.1 - 0.0009 19.0 0.0 0.00099 18.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CAR27930.1 - 0.0023 17.8 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 CAR27930.1 - 0.0031 17.8 0.0 0.0036 17.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain Band_7 PF01145.25 CAR27931.1 - 3.2e-22 79.4 1.9 4.8e-22 78.8 1.8 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family Atg14 PF10186.9 CAR27931.1 - 0.19 10.8 0.8 0.27 10.3 0.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OPT PF03169.15 CAR27932.1 - 8e-154 513.6 47.2 9.2e-154 513.4 47.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MARVEL PF01284.23 CAR27934.1 - 5.1e-28 97.9 15.8 7.3e-28 97.4 15.8 1.2 1 0 0 1 1 1 1 Membrane-associating domain HemY_N PF07219.13 CAR27934.1 - 1.6 8.9 3.8 2.1 8.5 0.2 2.6 3 0 0 3 3 3 0 HemY protein N-terminus BAR_2 PF10455.9 CAR27936.1 - 6.1e-93 311.1 13.1 8.5e-93 310.6 13.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CAR27936.1 - 1.5e-09 37.9 20.1 2.7e-07 30.5 8.3 3.2 3 0 0 3 3 3 3 BAR domain Peptidase_S30 PF01577.16 CAR27936.1 - 0.54 9.8 8.2 0.96 9.0 8.2 1.4 1 0 0 1 1 1 0 Potyvirus P1 protease DUF2464 PF10240.9 CAR27936.1 - 0.81 9.2 7.2 6.1 6.3 0.0 2.4 2 1 0 2 2 2 0 Multivesicular body subunit 12 Herpes_UL6 PF01763.16 CAR27936.1 - 1 7.8 7.4 1.4 7.3 7.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like SYF2 PF08231.12 CAR27937.1 - 7.1e-10 39.5 17.9 7.1e-10 39.5 17.9 1.8 2 0 0 2 2 2 1 SYF2 splicing factor Utp8 PF10395.9 CAR27938.1 - 2.2e-233 776.7 14.8 2.7e-233 776.5 14.8 1.1 1 0 0 1 1 1 1 Utp8 family LIDHydrolase PF10230.9 CAR27939.1 - 5.8e-66 222.8 0.2 6.7e-66 222.6 0.2 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 CAR27939.1 - 0.00015 21.2 0.1 0.00021 20.7 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CAR27939.1 - 0.00035 20.5 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR27939.1 - 0.001 19.8 0.0 0.0011 19.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CAR27939.1 - 0.0023 18.1 0.0 0.0042 17.2 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 CAR27939.1 - 0.0083 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1057 PF06342.12 CAR27939.1 - 0.0094 15.0 0.3 0.083 11.9 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ser_hydrolase PF06821.13 CAR27939.1 - 0.011 15.6 0.3 1.2 9.0 0.0 2.3 1 1 1 2 2 2 0 Serine hydrolase Peptidase_S9 PF00326.21 CAR27939.1 - 0.019 14.4 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PGAP1 PF07819.13 CAR27939.1 - 0.039 13.7 0.4 0.068 12.9 0.3 1.5 1 1 0 1 1 1 0 PGAP1-like protein DHQ_synthase PF01761.20 CAR27939.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase DUF3089 PF11288.8 CAR27939.1 - 0.15 11.6 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) TANGO2 PF05742.12 CAR27940.1 - 2.2e-40 139.3 0.0 2.7e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 CENP-O PF09496.10 CAR27941.1 - 5.8e-16 59.1 2.8 8e-16 58.7 0.2 2.2 2 1 0 2 2 2 1 Cenp-O kinetochore centromere component DUF1192 PF06698.11 CAR27941.1 - 0.07 13.2 0.4 0.07 13.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ZapB PF06005.12 CAR27941.1 - 0.088 13.3 2.7 0.093 13.2 0.8 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Osmo_CC PF08946.10 CAR27941.1 - 0.17 12.1 2.6 0.27 11.5 0.9 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Scs3p PF10261.9 CAR27942.1 - 1e-22 80.9 10.8 5.1e-16 58.9 1.0 2.3 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 CAR27942.1 - 0.00098 18.9 4.5 0.0012 18.6 3.5 1.7 1 1 0 1 1 1 1 PAP2 superfamily Orai-1 PF07856.12 CAR27942.1 - 0.066 12.9 2.0 0.11 12.1 2.0 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity SQHop_cyclase_C PF13243.6 CAR27943.1 - 3.4e-45 154.5 0.1 2.2e-44 151.9 0.0 2.0 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CAR27943.1 - 7.4e-37 127.0 0.0 4.7e-31 108.0 0.0 3.2 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 CAR27943.1 - 4.8e-27 93.4 0.7 1.2e-11 44.1 0.6 4.5 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 CAR27943.1 - 2.5e-05 23.5 0.1 9.8e-05 21.5 0.0 2.0 3 0 0 3 3 3 1 A-macroglobulin TED domain Pec_lyase PF09492.10 CAR27943.1 - 0.04 13.2 0.3 2.6 7.3 0.0 3.0 2 1 1 3 3 3 0 Pectic acid lyase Ubiq-assoc PF09145.10 CAR27944.1 - 4.2e-23 81.1 2.6 1.1e-22 79.7 2.6 1.8 1 0 0 1 1 1 1 Ubiquitin-associated TPR_2 PF07719.17 CAR27944.1 - 3.4e-06 26.8 1.0 2.3 8.6 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAR27944.1 - 6.7e-05 23.4 0.0 1.3 10.0 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR27944.1 - 0.00088 19.5 0.4 0.017 15.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAR27944.1 - 0.0082 15.9 3.9 18 5.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAR27944.1 - 0.011 16.2 1.4 0.43 11.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 CAR27944.1 - 0.012 15.7 0.4 0.25 11.5 0.0 2.7 2 0 0 2 2 2 0 DnaJ domain DUF3856 PF12968.7 CAR27944.1 - 0.023 14.8 0.0 0.068 13.2 0.0 1.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 CAR27944.1 - 0.1 12.7 0.3 8 6.6 0.1 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 CAR27944.1 - 0.39 11.5 1.7 28 5.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Nop10p PF04135.12 CAR27945.1 - 3.7e-21 74.9 0.6 4.3e-21 74.7 0.6 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DASH_Dad4 PF08650.10 CAR27946.1 - 1.3e-32 111.6 7.8 1.4e-32 111.5 7.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 NPV_P10 PF05531.12 CAR27946.1 - 0.0011 19.4 0.8 0.0013 19.2 0.8 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein HU-CCDC81_bac_2 PF18175.1 CAR27946.1 - 0.012 15.5 0.3 0.015 15.1 0.3 1.2 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 Syntaxin_2 PF14523.6 CAR27946.1 - 0.018 15.4 3.0 0.022 15.1 3.0 1.1 1 0 0 1 1 1 0 Syntaxin-like protein DUF3251 PF11622.8 CAR27946.1 - 0.02 14.5 0.4 0.02 14.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) CCDC53 PF10152.9 CAR27946.1 - 0.033 14.6 0.2 0.038 14.4 0.2 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4094 PF13334.6 CAR27946.1 - 0.12 12.8 0.4 1.4 9.3 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Pkinase PF00069.25 CAR27947.1 - 8.2e-44 149.9 0.4 2.4e-43 148.4 0.4 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27947.1 - 4e-20 72.2 0.1 1.4e-19 70.4 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR27947.1 - 1.7e-05 24.3 0.0 0.00013 21.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 CAR27947.1 - 0.0058 16.3 0.2 0.018 14.7 0.2 1.8 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 CDV3 PF15359.6 CAR27947.1 - 0.48 10.9 10.8 0.95 10.0 0.9 3.4 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 Peptidase_C13 PF01650.18 CAR27948.1 - 2.5e-46 158.3 1.0 3.5e-46 157.8 1.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family Thioredoxin_7 PF13899.6 CAR27949.1 - 9e-25 86.7 0.1 1.5e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 CAR27949.1 - 1.1e-17 64.0 0.0 2.5e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CAR27949.1 - 6.4e-13 48.3 0.1 1.2e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain C2-set PF05790.15 CAR27949.1 - 0.0044 17.2 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 Immunoglobulin C2-set domain Thioredoxin_2 PF13098.6 CAR27949.1 - 0.0048 17.3 0.0 0.0099 16.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Sas10_Utp3 PF04000.15 CAR27950.1 - 1.1e-05 25.9 2.5 1.1e-05 25.9 2.5 2.6 1 1 1 2 2 2 1 Sas10/Utp3/C1D family Macoilin PF09726.9 CAR27950.1 - 0.93 8.0 14.2 0.94 7.9 14.2 1.2 1 0 0 1 1 1 0 Macoilin family Peroxin-3 PF04882.12 CAR27952.1 - 4.1e-101 339.3 18.0 1.8e-98 330.6 18.0 2.0 1 1 0 1 1 1 1 Peroxin-3 Trep_Strep PF09605.10 CAR27952.1 - 0.096 12.7 0.0 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Skp1 PF01466.19 CAR27953.1 - 4.8e-24 84.2 0.2 8.2e-24 83.5 0.2 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CAR27953.1 - 2.3e-15 56.5 0.5 2.3e-14 53.3 0.2 2.5 2 1 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 CAR27953.1 - 0.032 14.4 0.1 0.45 10.8 0.1 2.0 1 1 0 1 1 1 0 BTB/POZ domain VASt PF16016.5 CAR27954.1 - 1.1e-70 237.0 0.1 6.2e-34 117.6 0.1 2.5 2 0 0 2 2 2 2 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CAR27954.1 - 1.2e-26 92.8 0.0 2.3e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 GRAM domain RdDM_RDM1 PF09187.10 CAR27954.1 - 0.13 12.4 0.5 0.28 11.3 0.5 1.5 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 adh_short PF00106.25 CAR27955.1 - 2.6e-16 59.6 0.0 4.8e-15 55.5 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR27955.1 - 3.3e-09 36.7 0.0 2.1e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR27955.1 - 2.9e-07 30.6 0.0 4.5e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CAR27955.1 - 0.00027 20.5 0.0 0.00038 20.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAR27955.1 - 0.0095 15.4 0.0 0.018 14.4 0.0 1.6 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 CAR27955.1 - 0.04 13.2 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Swi5 PF07061.11 CAR27956.1 - 5.6e-25 87.2 1.6 6.6e-25 87.0 1.6 1.1 1 0 0 1 1 1 1 Swi5 WEMBL PF05701.11 CAR27956.1 - 0.0014 17.4 2.1 0.0017 17.2 2.1 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light OmpH PF03938.14 CAR27956.1 - 0.0063 16.9 2.3 0.0091 16.3 2.3 1.2 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) RsbU_N PF08673.10 CAR27956.1 - 0.011 15.9 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain PEP-utilisers_N PF05524.13 CAR27956.1 - 0.037 14.2 1.0 0.041 14.1 1.0 1.3 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Herpes_UL6 PF01763.16 CAR27956.1 - 0.065 11.8 1.2 0.066 11.7 1.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Macoilin PF09726.9 CAR27956.1 - 0.086 11.4 1.8 0.091 11.3 1.8 1.0 1 0 0 1 1 1 0 Macoilin family DUF3810 PF12725.7 CAR27956.1 - 0.13 11.6 0.6 0.14 11.4 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) EURL PF06937.11 CAR27956.1 - 0.3 10.5 3.3 0.67 9.3 1.3 1.9 1 1 1 2 2 2 0 EURL protein DivIC PF04977.15 CAR27956.1 - 0.63 9.9 5.8 0.3 10.9 2.7 1.9 1 1 1 2 2 2 0 Septum formation initiator Ribonuc_2-5A PF06479.12 CAR27957.1 - 5e-46 156.0 0.3 1.1e-45 154.9 0.3 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 CAR27957.1 - 1.5e-41 142.5 0.0 4.3e-31 108.3 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR27957.1 - 1.8e-22 79.9 0.0 4.1e-21 75.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 CAR27957.1 - 0.0011 18.8 1.3 0.32 11.0 0.0 3.5 4 0 0 4 4 4 1 PQQ enzyme repeat Pkinase_fungal PF17667.1 CAR27957.1 - 0.012 14.5 0.0 0.031 13.1 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase PQQ_2 PF13360.6 CAR27957.1 - 0.014 15.0 0.0 3 7.4 0.0 2.3 1 1 0 1 1 1 0 PQQ-like domain Kdo PF06293.14 CAR27957.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_3 PF13570.6 CAR27957.1 - 0.059 13.9 0.3 13 6.5 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain Cnd3 PF12719.7 CAR27958.1 - 4.2e-94 315.0 8.5 6.3e-94 314.5 5.0 2.8 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 CAR27958.1 - 1.3e-08 34.4 3.5 2.2 8.8 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 CAR27958.1 - 1.1e-07 32.1 0.0 0.00012 22.4 0.0 3.1 1 1 2 3 3 3 3 HEAT repeats Cnd1 PF12717.7 CAR27958.1 - 2e-05 24.7 2.5 0.00014 21.9 1.0 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 FAD_syn PF06574.12 CAR27958.1 - 0.00033 20.6 0.3 0.001 19.0 0.1 1.9 2 0 0 2 2 2 1 FAD synthetase CNOT11 PF10155.9 CAR27958.1 - 0.0011 19.1 2.2 3 8.0 0.0 3.9 2 1 1 3 3 3 1 CCR4-NOT transcription complex subunit 11 HEAT_EZ PF13513.6 CAR27958.1 - 0.0044 17.5 0.0 93 3.7 0.0 4.8 5 0 0 5 5 5 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CAR27958.1 - 0.037 14.6 0.8 1.2 9.8 0.1 3.7 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region WD40 PF00400.32 CAR27959.1 - 1.4e-11 44.7 15.7 0.69 10.9 0.0 8.7 8 1 1 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR27959.1 - 2.3e-09 37.4 3.9 0.22 11.9 0.2 6.5 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain ABA_GPCR PF12430.8 CAR27960.1 - 1.1e-58 197.9 6.1 1.1e-58 197.9 6.1 3.1 3 1 0 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CAR27960.1 - 8.1e-17 61.1 0.3 1.9e-16 59.9 0.3 1.7 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal UXS1_N PF11803.8 CAR27960.1 - 1.1 9.6 3.9 18 5.8 0.3 3.0 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal Rbsn PF11464.8 CAR27961.1 - 9.4e-20 70.1 1.4 1.7e-19 69.2 1.4 1.5 1 0 0 1 1 1 1 Rabenosyn Rab binding domain FYVE PF01363.21 CAR27961.1 - 8.6e-15 54.6 24.0 3e-13 49.7 3.8 2.8 3 0 0 3 3 3 2 FYVE zinc finger DUF2732 PF10809.8 CAR27961.1 - 0.055 13.3 1.6 0.28 11.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) Cys_rich_CPXG PF14255.6 CAR27961.1 - 0.64 10.0 5.3 6.3 6.8 0.0 3.1 3 0 0 3 3 3 0 Cysteine-rich CPXCG FYVE_2 PF02318.16 CAR27961.1 - 1.4 9.1 13.5 0.79 9.9 1.0 3.3 2 0 0 2 2 2 0 FYVE-type zinc finger zf-AD PF07776.15 CAR27961.1 - 1.5 9.1 12.1 2.8 8.2 2.3 3.3 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-C2H2_4 PF13894.6 CAR27961.1 - 5.1 8.2 0.0 5.1 8.2 0.0 5.1 4 2 1 5 5 5 0 C2H2-type zinc finger AATF-Che1 PF13339.6 CAR27961.1 - 6.4 7.5 13.3 0.12 13.0 1.9 3.2 4 0 0 4 4 4 0 Apoptosis antagonizing transcription factor MIF4G PF02854.19 CAR27962.1 - 7.7e-31 107.4 43.8 6e-19 68.5 3.2 4.7 4 1 0 4 4 4 3 MIF4G domain Upf2 PF04050.14 CAR27962.1 - 1.2e-28 100.5 12.5 1.2e-28 100.5 12.5 3.0 1 1 1 2 2 2 1 Up-frameshift suppressor 2 GED PF02212.18 CAR27962.1 - 0.21 11.8 0.1 0.21 11.8 0.1 2.7 2 0 0 2 2 2 0 Dynamin GTPase effector domain Globin PF00042.22 CAR27962.1 - 0.55 10.8 3.5 3.4 8.3 0.4 3.6 4 0 0 4 4 4 0 Globin CDC27 PF09507.10 CAR27962.1 - 1.4 8.2 30.0 2.9 7.2 30.0 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 BUD22 PF09073.10 CAR27962.1 - 8.1 5.7 36.0 0.087 12.2 27.5 1.9 2 0 0 2 2 2 0 BUD22 Chorein_N PF12624.7 CAR27962.1 - 8.7 6.5 10.7 0.081 13.1 0.5 2.9 3 0 0 3 3 3 0 N-terminal region of Chorein or VPS13 SpoIIE PF07228.12 CAR27963.1 - 9.7e-37 126.8 0.0 1.2e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CAR27963.1 - 2.5e-06 27.3 0.0 0.001 18.8 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CAR27963.1 - 0.0032 17.1 0.2 0.0092 15.6 0.2 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PPC PF04151.15 CAR27963.1 - 0.12 13.5 0.5 0.32 12.1 0.5 1.7 1 0 0 1 1 1 0 Bacterial pre-peptidase C-terminal domain ATP-synt_E PF05680.12 CAR27964.1 - 3.7e-14 52.8 0.0 4.1e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain PBP PF01161.20 CAR27965.1 - 6.4e-05 23.3 0.1 0.00013 22.3 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_M1 PF01433.20 CAR27966.1 - 4.1e-68 229.2 0.1 8.6e-68 228.2 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CAR27966.1 - 4e-49 167.3 1.7 4e-49 167.3 1.7 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CAR27966.1 - 1.6e-40 139.6 0.1 3.4e-40 138.5 0.0 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Abhydrolase_6 PF12697.7 CAR27967.1 - 7.3e-19 69.2 0.0 1e-18 68.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CAR27967.1 - 2.5e-13 50.3 0.1 3.5e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR27967.1 - 6.2e-10 38.8 0.1 8.1e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CAR27967.1 - 0.0008 19.2 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 CAR27967.1 - 0.0012 18.7 0.0 0.0028 17.5 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 CAR27967.1 - 0.0015 18.1 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 CAR27967.1 - 0.014 15.6 0.5 0.18 11.9 0.5 2.2 1 1 0 1 1 1 0 Thioesterase domain VirJ PF06057.11 CAR27967.1 - 0.044 13.7 0.0 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) CN_hydrolase PF00795.22 CAR27968.1 - 1e-46 159.4 0.0 1.3e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 CAR27968.1 - 5.2e-23 81.4 0.0 2.2e-22 79.4 0.0 1.9 1 1 0 1 1 1 1 NAD synthase Asparaginase PF00710.20 CAR27969.1 - 6.1e-56 189.0 0.0 1.5e-55 187.8 0.0 1.7 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CAR27969.1 - 8.5e-20 71.1 0.1 2.1e-19 69.8 0.0 1.7 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Oxysterol_BP PF01237.18 CAR27970.1 - 3.4e-99 332.2 3.4 2.8e-98 329.2 3.4 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 CAR27970.1 - 7.4e-29 99.9 1.3 1.7e-28 98.7 0.5 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CAR27970.1 - 0.00016 22.1 1.8 0.0021 18.6 0.7 3.0 2 0 0 2 2 2 1 PH domain Suppressor_P21 PF11479.8 CAR27970.1 - 0.021 15.0 0.2 0.053 13.7 0.2 1.6 1 0 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain 2-Hacid_dh_C PF02826.19 CAR27971.1 - 2.5e-39 134.5 0.0 2e-38 131.6 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAR27971.1 - 2.3e-19 69.4 0.1 3.5e-19 68.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CAR27971.1 - 0.0015 18.7 0.0 0.0048 17.1 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 CAR27971.1 - 0.028 14.5 0.2 2.8 8.0 0.0 2.9 2 2 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 CAR27971.1 - 0.077 13.3 0.1 26 5.1 0.0 3.1 2 1 1 3 3 3 0 TrkA-N domain ResIII PF04851.15 CAR27972.1 - 3.1e-30 105.4 0.9 4.6e-30 104.8 0.1 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAR27972.1 - 2.6e-16 60.0 0.4 9.1e-14 51.7 0.0 3.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAR27972.1 - 9.4e-16 58.1 0.1 2.3e-15 56.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CAR27972.1 - 9.1e-10 38.6 0.3 9.1e-10 38.6 0.3 2.1 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 CAR27972.1 - 2.3e-05 23.8 0.0 4.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CAR27972.1 - 0.0024 18.2 0.0 0.013 15.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR27972.1 - 0.045 13.5 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CAR27972.1 - 8.6 6.1 7.2 1 9.1 0.2 2.6 3 1 1 4 4 4 0 AAA domain SAM35 PF10806.8 CAR27973.1 - 3.3e-47 159.9 0.5 3.5e-46 156.6 0.1 2.1 2 0 0 2 2 2 1 SAM35, subunit of SAM coomplex Tcf25 PF04910.14 CAR27974.1 - 1e-77 261.6 0.7 1.5e-77 261.1 0.7 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Ipi1_N PF12333.8 CAR27975.1 - 9e-24 84.0 0.2 9e-24 84.0 0.2 2.6 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation DUF3730 PF12530.8 CAR27975.1 - 0.0017 18.0 2.2 0.0048 16.5 1.9 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) Cnd1 PF12717.7 CAR27975.1 - 0.0024 17.9 0.6 0.004 17.2 0.6 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CAR27975.1 - 0.011 15.9 0.7 13 6.3 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat DUF5071 PF16804.5 CAR27975.1 - 0.063 13.5 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) V-ATPase_H_C PF11698.8 CAR27975.1 - 0.066 13.3 2.3 0.17 12.0 0.2 2.7 3 1 1 4 4 4 0 V-ATPase subunit H HEAT_2 PF13646.6 CAR27975.1 - 0.15 12.5 0.0 1.9 8.9 0.0 2.8 3 1 0 3 3 3 0 HEAT repeats Acetyltransf_1 PF00583.25 CAR27976.1 - 6.6e-14 52.1 0.1 8.5e-14 51.8 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR27976.1 - 2.4e-13 50.1 0.1 3.2e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR27976.1 - 8.3e-12 45.4 0.3 1.2e-11 44.9 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAR27976.1 - 1.2e-05 25.2 0.1 2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 CAR27976.1 - 0.0048 17.0 0.1 0.0051 17.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CAR27976.1 - 0.012 15.7 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CAR27976.1 - 0.028 13.9 0.5 0.041 13.3 0.5 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 CAR27976.1 - 0.031 14.9 0.0 0.035 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CAR27976.1 - 0.086 13.0 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase DnaJ PF00226.31 CAR27977.1 - 2.9e-17 62.5 0.4 8.1e-17 61.1 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain FAM176 PF14851.6 CAR27977.1 - 4.4 7.0 7.5 11 5.7 7.5 1.6 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.9 CAR27977.1 - 9.8 5.2 15.7 17 4.4 15.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRM_9 PF18444.1 CAR27978.1 - 2.3e-31 107.4 0.2 5e-31 106.4 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif TAP_C PF03943.13 CAR27978.1 - 9.3e-14 50.8 1.2 1.2e-13 50.4 0.1 1.9 2 0 0 2 2 2 1 TAP C-terminal domain LRR_9 PF14580.6 CAR27978.1 - 2.1e-07 30.6 2.7 9.2e-07 28.5 2.8 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 CAR27978.1 - 0.0003 21.1 6.9 0.025 15.0 6.9 3.0 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAR27978.1 - 0.037 13.8 0.9 0.13 12.1 0.9 2.0 1 0 0 1 1 1 0 Leucine rich repeat Orthopox_B11R PF07033.11 CAR27979.1 - 0.053 13.3 0.4 0.14 12.0 0.4 1.6 1 0 0 1 1 1 0 Orthopoxvirus B11R protein Cyt-b5 PF00173.28 CAR27980.1 - 5.4e-12 45.7 0.0 7.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PX PF00787.24 CAR27981.1 - 4.6e-05 23.4 0.1 9.1e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CAR27981.1 - 0.0044 16.6 5.6 0.0074 15.9 5.6 1.3 1 0 0 1 1 1 1 Vps5 C terminal like TetR_C_24 PF17932.1 CAR27981.1 - 0.012 15.9 0.8 1.1 9.6 0.4 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain GCN5L1 PF06320.13 CAR27981.1 - 0.17 12.0 6.4 1.5 9.0 0.0 2.9 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) GTP_EFTU PF00009.27 CAR27982.1 - 2.3e-67 226.3 0.5 3.3e-67 225.8 0.5 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CAR27982.1 - 8.7e-33 112.7 0.0 4.5e-32 110.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CAR27982.1 - 1.3e-22 79.6 0.0 3.2e-22 78.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CAR27982.1 - 6.6e-14 52.1 0.2 2.4e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CAR27982.1 - 1.9e-13 50.3 0.0 6.7e-13 48.5 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CAR27982.1 - 0.00027 21.0 0.2 0.00055 20.0 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ERCC4 PF02732.15 CAR27983.1 - 1e-19 71.3 0.5 2.1e-19 70.2 0.5 1.6 1 0 0 1 1 1 1 ERCC4 domain HTH_27 PF13463.6 CAR27983.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain HHH_8 PF14716.6 CAR27983.1 - 0.14 12.5 0.0 0.51 10.7 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain Sugar_tr PF00083.24 CAR27984.1 - 1.3e-92 311.0 20.7 1.7e-52 178.8 4.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CAR27984.1 - 1.6e-24 86.5 34.4 4.3e-21 75.2 13.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 CAR27984.1 - 0.022 15.3 7.1 0.033 14.7 3.9 2.7 2 0 0 2 2 2 0 Phage holin family 2 ATP-synt_S1 PF05827.12 CAR27984.1 - 2.3 8.1 6.5 0.23 11.3 0.6 2.2 2 0 0 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) BAR PF03114.18 CAR27985.1 - 4.5e-60 203.3 5.0 5.6e-60 203.0 5.0 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CAR27985.1 - 6.6e-14 51.2 0.0 1.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR27985.1 - 1.1e-11 44.4 0.1 1.9e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR27985.1 - 1.3e-07 31.2 0.0 2.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain LRRC37AB_C PF14914.6 CAR27985.1 - 0.033 14.1 0.7 0.072 13.0 0.7 1.5 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF1931 PF09123.11 CAR27985.1 - 0.11 12.7 0.2 0.38 10.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) RhoGAP PF00620.27 CAR27986.1 - 2.4e-32 111.9 1.3 7.2e-21 74.6 0.0 3.1 3 0 0 3 3 3 2 RhoGAP domain DUF3381 PF11861.8 CAR27986.1 - 0.75 9.6 10.6 0.23 11.3 5.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) RR_TM4-6 PF06459.12 CAR27986.1 - 4.4 7.1 9.4 0.21 11.4 2.5 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ThiF PF00899.21 CAR27987.1 - 5.1e-69 232.3 0.0 6.7e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 CAR27987.1 - 9.3e-05 22.5 12.8 0.0019 18.1 0.8 3.2 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site Utp13 PF08625.11 CAR27987.1 - 0.039 13.9 0.1 0.084 12.8 0.1 1.6 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Polysacc_synt_2 PF02719.15 CAR27987.1 - 0.16 11.0 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CDC45 PF02724.14 CAR27987.1 - 3.7 5.7 7.6 6.2 5.0 7.6 1.3 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 CAR27987.1 - 7.3 5.9 9.0 16 4.7 9.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Iso_dh PF00180.20 CAR27988.1 - 4.3e-101 338.5 0.1 5.4e-101 338.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase C2 PF00168.30 CAR27989.1 - 0.13 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 C2 domain UBA PF00627.31 CAR27990.1 - 6e-07 29.2 0.0 1.6e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.16 CAR27990.1 - 4.3e-05 23.1 0.0 0.00046 19.8 0.0 2.4 2 0 0 2 2 2 1 CUE domain UBA_4 PF14555.6 CAR27990.1 - 5e-05 23.0 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain rRNA_proc-arch PF13234.6 CAR27990.1 - 0.019 14.9 0.7 0.031 14.2 0.7 1.3 1 0 0 1 1 1 0 rRNA-processing arch domain HSF_DNA-bind PF00447.17 CAR27991.1 - 6.6e-27 94.0 1.1 6.6e-27 94.0 1.1 2.3 2 1 1 3 3 3 1 HSF-type DNA-binding DUF4407 PF14362.6 CAR27991.1 - 5 6.4 5.1 14 4.9 5.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) REC114-like PF15165.6 CAR27991.1 - 5.8 6.6 12.7 2.7 7.7 10.0 1.8 2 0 0 2 2 2 0 Meiotic recombination protein REC114-like Actin PF00022.19 CAR27992.1 - 6e-24 84.4 0.0 3.1e-15 55.7 0.0 3.8 3 1 0 3 3 3 3 Actin Actin_micro PF17003.5 CAR27992.1 - 1.3e-11 44.4 0.5 0.00012 21.4 0.1 2.5 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 CAR27992.1 - 0.0017 17.3 0.0 0.046 12.5 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein EST1 PF10374.9 CAR27992.1 - 0.013 16.1 1.3 0.95 10.1 0.1 2.9 3 0 0 3 3 3 0 Telomerase activating protein Est1 PilM_2 PF11104.8 CAR27992.1 - 0.027 13.5 0.0 2 7.4 0.0 2.8 3 0 0 3 3 3 0 Type IV pilus assembly protein PilM; BAR_3_WASP_bdg PF10456.9 CAR27992.1 - 0.31 10.4 2.8 0.55 9.6 0.5 2.1 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein CoA_binding PF02629.19 CAR27993.1 - 1.9e-24 86.2 3.2 2.2e-24 85.9 1.2 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CAR27993.1 - 6.2e-24 84.6 0.2 9.7e-24 83.9 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CAR27993.1 - 2.8e-06 27.2 0.0 5.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CAR27993.1 - 0.0003 21.3 0.0 0.00058 20.3 0.0 1.5 1 0 0 1 1 1 1 CoA binding domain TPK_catalytic PF04263.16 CAR27994.1 - 3e-31 107.9 0.1 7.8e-31 106.6 0.1 1.6 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CAR27994.1 - 7.1e-11 41.7 0.1 1.5e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TFIID-18kDa PF02269.16 CAR27995.1 - 3e-36 123.3 0.8 6.1e-35 119.1 0.2 2.5 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit AAA PF00004.29 CAR27996.1 - 0.00089 19.7 0.5 0.0064 16.9 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DBB PF14545.6 CAR27996.1 - 0.077 12.9 0.2 7.2 6.5 0.0 3.2 3 0 0 3 3 3 0 Dof, BCAP, and BANK (DBB) motif, KH_8 PF17903.1 CAR27997.1 - 8.5e-05 22.6 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CAR27997.1 - 0.11 12.3 0.3 0.27 11.1 0.3 1.6 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 CAR27998.1 - 5.5e-96 322.3 21.7 1.8e-46 158.9 4.9 4.1 2 1 2 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins Vac_ImportDeg PF09783.9 CAR27998.1 - 0.065 13.0 1.6 0.088 12.6 0.1 2.0 2 1 0 2 2 2 0 Vacuolar import and degradation protein DUF748 PF05359.11 CAR27998.1 - 0.069 13.3 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) G-patch_2 PF12656.7 CAR27999.1 - 2.6e-17 62.6 0.4 2.6e-17 62.6 0.4 2.7 3 1 0 3 3 3 1 G-patch domain She9_MDM33 PF05546.11 CAR28000.1 - 2.1e-83 279.0 13.8 2.1e-83 279.0 13.8 2.1 2 0 0 2 2 2 1 She9 / Mdm33 family PsbH PF00737.20 CAR28000.1 - 0.042 13.6 0.6 0.083 12.6 0.6 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Folliculin PF11704.8 CAR28000.1 - 0.044 13.7 1.3 0.29 11.0 1.3 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF1247 PF06851.11 CAR28000.1 - 0.094 12.7 1.3 3.5 7.6 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1247) DUF883 PF05957.13 CAR28000.1 - 0.42 11.3 17.3 0.44 11.2 0.6 3.9 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Cob_adeno_trans PF01923.18 CAR28000.1 - 1.7 8.7 5.8 3.8 7.6 0.1 2.8 2 1 1 3 3 3 0 Cobalamin adenosyltransferase DUF948 PF06103.11 CAR28000.1 - 2.4 8.5 4.7 34 4.8 0.2 3.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4407 PF14362.6 CAR28000.1 - 8.2 5.7 19.8 0.14 11.5 10.5 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) AAA PF00004.29 CAR28001.1 - 1.9e-45 154.5 0.0 4.6e-45 153.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CAR28001.1 - 7e-08 32.3 0.2 4.2e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CAR28001.1 - 7.1e-08 32.8 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CAR28001.1 - 2.6e-07 31.2 0.0 3.5e-05 24.3 0.0 3.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CAR28001.1 - 9.8e-07 28.9 0.1 4.5e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 CAR28001.1 - 7.4e-05 22.5 0.2 0.00018 21.2 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CAR28001.1 - 8.1e-05 22.9 1.2 0.0067 16.7 0.0 2.7 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.13 CAR28001.1 - 0.00015 21.0 0.0 0.00026 20.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CAR28001.1 - 0.0004 20.2 0.0 0.0012 18.6 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 CAR28001.1 - 0.0014 18.4 0.0 0.0031 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CAR28001.1 - 0.0014 18.6 0.0 0.0049 16.8 0.0 1.9 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 CAR28001.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CAR28001.1 - 0.003 17.9 0.0 0.0063 16.9 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 CAR28001.1 - 0.0032 18.0 0.0 0.014 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CAR28001.1 - 0.0039 16.7 0.0 0.032 13.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 CAR28001.1 - 0.004 17.2 0.0 0.0086 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CAR28001.1 - 0.0042 16.3 0.0 0.0083 15.4 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain TniB PF05621.11 CAR28001.1 - 0.0048 16.3 0.0 0.33 10.4 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 CAR28001.1 - 0.0062 15.9 0.1 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CAR28001.1 - 0.0064 16.4 0.0 0.02 14.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CAR28001.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CAR28001.1 - 0.008 16.3 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CAR28001.1 - 0.013 15.2 0.0 0.22 11.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CAR28001.1 - 0.017 14.8 0.1 0.052 13.3 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein NACHT PF05729.12 CAR28001.1 - 0.019 14.9 0.1 0.13 12.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 CAR28001.1 - 0.02 15.1 0.0 0.054 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CAR28001.1 - 0.035 14.0 0.1 0.44 10.4 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 CAR28001.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAR28001.1 - 0.071 12.7 0.3 0.32 10.5 0.1 2.0 1 1 1 2 2 2 0 AAA domain HTH_21 PF13276.6 CAR28001.1 - 0.12 12.5 0.1 0.45 10.7 0.0 2.0 2 0 0 2 2 1 0 HTH-like domain AAA_19 PF13245.6 CAR28001.1 - 0.15 12.4 0.1 0.39 11.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain Glyco_transf_22 PF03901.17 CAR28002.1 - 2.4e-66 224.7 22.8 2.8e-66 224.5 22.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family IBN_N PF03810.19 CAR28003.1 - 6.1e-20 70.9 0.5 4.6e-19 68.1 0.9 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 CAR28003.1 - 0.0015 17.5 0.9 0.0015 17.5 0.9 3.3 4 1 0 4 4 4 1 Cse1 Vac14_Fab1_bd PF12755.7 CAR28003.1 - 0.11 13.1 0.3 1 10.0 0.1 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region CBFD_NFYB_HMF PF00808.23 CAR28004.1 - 1e-13 51.3 1.3 1.7e-13 50.7 1.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CAR28004.1 - 0.06 13.7 0.1 0.06 13.7 0.1 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Utp12 PF04003.12 CAR28005.1 - 2.9e-21 75.8 4.0 6.1e-21 74.8 4.0 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family RAB3GAP2_N PF14655.6 CAR28005.1 - 0.025 13.9 0.0 4.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RNA_pol_3_Rpc31 PF11705.8 CAR28005.1 - 2.2 8.5 15.7 3.9 7.7 15.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Pribosyltran PF00156.27 CAR28006.1 - 5.6e-09 35.7 0.0 8.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain EC042_2821 PF18740.1 CAR28006.1 - 0.024 14.5 0.2 0.078 12.9 0.1 1.7 1 1 1 2 2 2 0 EC042_2821-lke REase Fe-ADH PF00465.19 CAR28006.1 - 0.034 13.0 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase 3Beta_HSD PF01073.19 CAR28006.1 - 0.13 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family IU_nuc_hydro PF01156.19 CAR28007.1 - 5.4e-75 252.8 0.0 6.4e-75 252.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.22 CAR28008.1 - 1.8e-60 205.0 0.1 2.3e-60 204.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cyclin_N PF00134.23 CAR28008.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain DIT1_PvcA PF05141.12 CAR28009.1 - 3.1e-99 331.9 0.0 2.4e-98 329.0 0.0 2.0 2 0 0 2 2 2 1 Pyoverdine/dityrosine biosynthesis protein S1 PF00575.23 CAR28010.1 - 4.6e-18 65.3 0.1 6.7e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 CAR28010.1 - 1e-17 64.2 0.0 2.1e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 CAR28010.1 - 4.7e-06 26.9 0.0 7.9e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 Ribosomal_L13 PF00572.18 CAR28011.1 - 4e-45 153.1 0.1 4.8e-45 152.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L13 RNA_pol_Rpb2_6 PF00562.28 CAR28012.1 - 2.8e-126 421.7 0.1 5e-126 420.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CAR28012.1 - 2.2e-73 246.1 0.1 3.8e-73 245.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CAR28012.1 - 2e-52 177.6 0.0 4.1e-52 176.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CAR28012.1 - 8.1e-34 115.9 0.1 2e-33 114.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CAR28012.1 - 8.5e-26 90.0 0.3 2e-25 88.8 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CAR28012.1 - 2.3e-24 85.3 0.1 6.4e-24 83.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CAR28012.1 - 4.5e-19 68.8 1.9 4.5e-19 68.8 1.9 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Ribosomal_L23 PF00276.20 CAR28013.1 - 7.6e-11 42.2 0.0 1.5e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 ABC2_membrane PF01061.24 CAR28015.1 - 6.2e-79 264.3 53.0 1.3e-41 142.3 20.8 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 CAR28015.1 - 4.6e-39 134.1 0.2 4.4e-17 62.9 0.0 3.5 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 CAR28015.1 - 7.7e-37 125.1 4.5 3.6e-32 110.1 0.3 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CAR28015.1 - 2.7e-15 56.8 0.4 2.7e-14 53.6 0.0 2.8 4 0 0 4 4 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 CAR28015.1 - 1.1e-08 34.9 0.5 4.1e-07 29.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAR28015.1 - 8.6e-08 32.7 0.2 3.7e-05 24.2 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAR28015.1 - 2.3e-05 24.3 0.3 0.00067 19.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 CAR28015.1 - 3.8e-05 23.7 0.2 0.12 12.3 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_21 PF13304.6 CAR28015.1 - 6.4e-05 22.9 0.1 0.73 9.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CAR28015.1 - 0.00028 21.1 0.3 0.32 11.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 CAR28015.1 - 0.0006 19.4 2.2 0.59 9.7 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CAR28015.1 - 0.00069 19.3 2.1 0.012 15.3 0.4 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 CAR28015.1 - 0.00072 19.7 1.1 0.24 11.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.19 CAR28015.1 - 0.00084 18.8 0.0 0.16 11.4 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CAR28015.1 - 0.0011 19.5 0.8 0.027 15.0 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CAR28015.1 - 0.0021 18.6 0.4 0.56 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 CAR28015.1 - 0.0033 17.8 0.0 2.2 8.7 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 CAR28015.1 - 0.0055 16.1 0.0 0.76 9.1 0.0 2.3 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_28 PF13521.6 CAR28015.1 - 0.017 15.4 5.3 0.14 12.4 0.3 3.1 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CAR28015.1 - 0.022 14.5 1.5 2.8 7.6 0.6 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CAR28015.1 - 0.024 14.6 0.3 0.42 10.6 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 CAR28015.1 - 0.027 13.6 0.1 2.4 7.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 CAR28015.1 - 0.051 13.3 0.2 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_13 PF13166.6 CAR28015.1 - 0.097 11.3 0.0 16 4.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain OCD_Mu_crystall PF02423.15 CAR28015.1 - 0.11 11.4 0.0 0.51 9.2 0.0 1.9 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family ATPase_2 PF01637.18 CAR28015.1 - 0.12 12.2 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea HalX PF08663.10 CAR28015.1 - 0.21 11.9 3.6 1.5 9.2 0.2 2.4 2 0 0 2 2 2 0 HalX domain Roc PF08477.13 CAR28015.1 - 0.43 10.8 1.5 47 4.2 0.1 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 CAR28015.1 - 0.52 10.7 1.5 8.7 6.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC2_membrane_3 PF12698.7 CAR28015.1 - 2.2 7.3 39.9 0.081 12.0 19.1 3.1 2 1 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 CAR28016.1 - 3e-76 255.5 53.6 9.3e-39 133.0 22.5 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CAR28016.1 - 2.7e-38 131.6 0.1 5.1e-18 65.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 CAR28016.1 - 2.2e-30 104.4 9.9 1.3e-27 95.5 0.1 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CAR28016.1 - 9.1e-16 58.3 0.0 4.5e-15 56.0 0.0 2.2 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_16 PF13191.6 CAR28016.1 - 1.5e-06 28.7 0.1 0.00023 21.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CAR28016.1 - 7.5e-06 25.6 0.1 5.8e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CAR28016.1 - 1.6e-05 24.8 0.1 0.00033 20.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 CAR28016.1 - 0.00011 22.4 0.0 0.037 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CAR28016.1 - 0.00016 21.2 0.1 0.014 14.8 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 CAR28016.1 - 0.00024 21.7 1.2 0.036 14.6 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_21 PF13304.6 CAR28016.1 - 0.00031 20.6 0.0 0.72 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAR28016.1 - 0.00061 19.5 0.8 0.01 15.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 CAR28016.1 - 0.00089 18.9 2.4 0.17 11.4 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CAR28016.1 - 0.0018 18.6 0.0 0.61 10.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 CAR28016.1 - 0.002 18.1 0.1 2.7 7.9 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_23 PF13476.6 CAR28016.1 - 0.0066 17.0 0.2 0.087 13.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CAR28016.1 - 0.06 13.8 0.0 11 6.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) OCD_Mu_crystall PF02423.15 CAR28016.1 - 0.062 12.2 0.0 0.96 8.3 0.0 2.3 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family AAA_30 PF13604.6 CAR28016.1 - 0.071 12.8 1.0 5.5 6.7 0.3 2.5 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 CAR28016.1 - 0.1 11.9 0.0 3 7.1 0.0 2.5 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_17 PF13207.6 CAR28016.1 - 0.19 12.1 0.5 9.5 6.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CAR28016.1 - 0.33 11.2 5.7 1.1 9.5 0.2 3.2 3 0 0 3 3 3 0 AAA domain ABC2_membrane PF01061.24 CAR28017.1 - 1.1e-80 270.0 40.9 9.4e-42 142.8 17.4 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CAR28017.1 - 2.2e-37 128.6 0.0 7.4e-18 65.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CAR28017.1 - 1.1e-34 118.1 12.1 3e-31 107.2 0.2 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CAR28017.1 - 1.2e-16 61.1 0.0 6.1e-16 58.8 0.0 2.2 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CAR28017.1 - 1.1e-08 35.7 0.9 5.4e-06 26.9 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_25 PF13481.6 CAR28017.1 - 3.1e-07 30.1 0.4 9.1e-06 25.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR28017.1 - 2.4e-05 24.5 0.0 0.23 11.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.6 CAR28017.1 - 6.5e-05 22.9 0.4 0.23 11.2 0.0 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CAR28017.1 - 7.3e-05 22.7 0.4 0.00074 19.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CAR28017.1 - 0.00035 20.9 0.1 0.35 11.1 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CAR28017.1 - 0.00053 19.7 1.0 0.0088 15.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 CAR28017.1 - 0.0013 18.7 0.0 1.2 9.0 0.0 2.8 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.19 CAR28017.1 - 0.0027 17.2 0.1 0.16 11.4 0.0 2.7 3 0 0 3 3 2 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 CAR28017.1 - 0.0039 17.7 1.3 0.43 11.1 0.0 3.4 4 0 0 4 4 3 1 AAA domain NTPase_1 PF03266.15 CAR28017.1 - 0.0062 16.5 0.5 1.9 8.4 0.1 3.2 3 0 0 3 3 3 1 NTPase AAA_30 PF13604.6 CAR28017.1 - 0.016 15.0 0.7 3.6 7.3 0.4 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CAR28017.1 - 0.035 13.7 2.3 3.2 7.3 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 CAR28017.1 - 0.059 12.7 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_23 PF13476.6 CAR28017.1 - 0.11 13.0 5.4 0.065 13.7 0.7 2.7 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 CAR28017.1 - 0.15 11.2 0.2 9.2 5.4 0.0 2.8 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.6 CAR28017.1 - 0.15 12.3 7.5 0.53 10.5 1.4 3.2 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 CAR28017.1 - 0.16 12.4 0.2 12 6.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CAR28017.1 - 0.24 11.8 0.3 39 4.7 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ABC2_membrane_3 PF12698.7 CAR28017.1 - 5.5 6.0 36.2 0.29 10.2 17.7 3.0 2 1 0 2 2 2 0 ABC-2 family transporter protein ISN1 PF06437.11 CAR28018.1 - 2.4e-175 583.4 0.0 2.7e-175 583.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Choline_transpo PF04515.12 CAR28019.1 - 1.9e-73 247.5 18.8 1.9e-73 247.5 18.8 2.2 2 1 0 2 2 2 1 Plasma-membrane choline transporter Xpo1 PF08389.12 CAR28020.1 - 2.1e-26 92.8 3.3 1.8e-25 89.7 0.5 3.7 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 CAR28020.1 - 4.1e-09 36.2 3.5 8e-08 32.1 1.3 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.22 CAR28020.1 - 0.004 17.3 0.1 11 6.7 0.0 3.5 2 0 0 2 2 2 2 HEAT repeat LSM PF01423.22 CAR28021.1 - 4.1e-15 55.2 0.0 4.7e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CAR28021.1 - 0.0052 16.4 0.2 0.0098 15.5 0.0 1.5 2 0 0 2 2 2 1 Hfq protein HEPN-like_int PF18867.1 CAR28022.1 - 3.2 7.6 7.4 0.32 10.9 2.0 2.0 3 0 0 3 3 3 0 HEPN-like integron domain LMBR1 PF04791.16 CAR28022.1 - 9.5 5.0 8.8 13 4.5 8.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TRAPPC9-Trs120 PF08626.11 CAR28023.1 - 9.8e-302 1003.7 15.4 1.2e-301 1003.4 15.4 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 CAR28023.1 - 0.0023 18.2 0.3 0.0058 16.9 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Proteasome PF00227.26 CAR28024.1 - 4.7e-47 159.9 0.1 6.1e-47 159.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CAR28024.1 - 3.3e-14 52.0 0.0 3.3e-14 52.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Formyl_trans_N PF00551.19 CAR28025.1 - 2.4e-53 180.6 0.0 2.8e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Glyco_trans_4_4 PF13579.6 CAR28025.1 - 0.09 13.2 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain PINIT PF14324.6 CAR28026.1 - 5e-40 137.2 0.8 9.3e-40 136.3 0.8 1.5 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 CAR28026.1 - 1.8e-20 72.4 7.1 3.3e-20 71.6 7.1 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 CAR28026.1 - 1.2e-10 40.9 0.0 2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 CAR28026.1 - 6.8e-05 22.6 0.8 0.00014 21.6 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit YopE_N PF09020.10 CAR28026.1 - 0.00047 20.4 0.1 0.002 18.4 0.1 2.1 1 0 0 1 1 1 1 YopE, N terminal zf-RING_UBOX PF13445.6 CAR28026.1 - 0.011 15.7 1.5 0.026 14.5 1.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR28026.1 - 0.7 9.8 4.2 1.5 8.7 4.2 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ICMT PF04140.14 CAR28027.1 - 5e-29 100.6 0.4 1.1e-28 99.4 0.4 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CAR28027.1 - 2.4e-11 44.0 2.0 2.4e-11 44.0 2.0 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 CAR28027.1 - 3.3e-06 26.8 1.3 4.4e-06 26.4 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Rab5ip PF07019.12 CAR28027.1 - 2 9.1 10.1 4.4 8.0 8.1 2.5 1 1 1 2 2 2 0 Rab5-interacting protein (Rab5ip) zf-HIT PF04438.16 CAR28028.1 - 0.0005 19.9 8.5 0.00081 19.2 8.5 1.3 1 0 0 1 1 1 1 HIT zinc finger LsmAD PF06741.13 CAR28028.1 - 0.029 14.9 7.0 0.074 13.6 2.6 2.6 1 1 1 2 2 2 0 LsmAD domain Carn_acyltransf PF00755.20 CAR28029.1 - 1e-172 575.9 0.0 1.2e-172 575.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase BB_PF PF18063.1 CAR28029.1 - 0.073 12.7 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Beta barrel Pore-forming domain Tropomyosin_1 PF12718.7 CAR28030.1 - 0.0003 21.0 3.2 0.00043 20.5 3.2 1.3 1 0 0 1 1 1 1 Tropomyosin like TMF_TATA_bd PF12325.8 CAR28030.1 - 0.013 15.8 3.5 0.015 15.5 1.7 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DER1 PF04511.15 CAR28031.1 - 1.8e-48 165.0 9.8 2.1e-48 164.8 9.8 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 CAR28031.1 - 0.0017 18.4 5.0 0.0023 18.0 5.0 1.2 1 0 0 1 1 1 1 Rhomboid family DUF2070 PF09843.9 CAR28031.1 - 2.1 6.5 8.9 2.7 6.2 8.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Nop25 PF09805.9 CAR28032.1 - 7.9e-33 113.8 24.0 7.9e-33 113.8 24.0 1.5 1 1 0 1 1 1 1 Nucleolar protein 12 (25kDa) Med4 PF10018.9 CAR28032.1 - 0.21 11.3 14.3 0.076 12.7 11.2 1.8 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 OMS28_porin PF03532.13 CAR28032.1 - 3.6 6.7 8.2 0.8 8.9 3.9 1.9 2 0 0 2 2 2 0 OMS28 porin EXS PF03124.14 CAR28033.1 - 1.4e-48 166.0 29.0 1.7e-48 165.7 29.0 1.0 1 0 0 1 1 1 1 EXS family Ribosomal_L2_C PF03947.18 CAR28034.1 - 2.5e-54 182.8 1.8 4.9e-54 181.9 1.8 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CAR28034.1 - 8.9e-26 89.7 0.1 2.9e-25 88.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Peptidase_M28 PF04389.17 CAR28035.1 - 1.7e-29 102.9 0.0 2.4e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CAR28035.1 - 1.9e-06 27.7 0.0 2.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ATP-synt_D PF01813.17 CAR28036.1 - 3.6e-71 239.1 2.6 5.3e-71 238.5 2.6 1.3 1 0 0 1 1 1 1 ATP synthase subunit D DUF4665 PF15679.5 CAR28036.1 - 0.0049 17.5 6.0 0.012 16.2 2.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4665) BLOC1_2 PF10046.9 CAR28036.1 - 0.088 13.1 7.1 4 7.8 2.3 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YabA PF06156.13 CAR28036.1 - 0.67 10.6 7.7 2.1 9.0 4.7 2.4 2 0 0 2 2 2 0 Initiation control protein YabA TPR_15 PF13429.6 CAR28037.1 - 0.0019 17.5 0.3 1.4 8.0 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAR28037.1 - 0.0036 18.0 2.5 47 5.2 0.0 6.2 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 CAR28037.1 - 0.099 13.2 0.1 1.2 9.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Zeta_toxin PF06414.12 CAR28037.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AFG1_ATPase PF03969.16 CAR28038.1 - 6.3e-76 255.6 0.0 1.3e-72 244.7 0.0 2.3 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 CAR28038.1 - 0.0001 22.8 0.2 0.014 15.8 0.2 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR28038.1 - 0.0034 17.7 0.0 0.0079 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CAR28038.1 - 0.0052 16.7 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.6 CAR28038.1 - 0.0079 16.2 0.3 0.041 13.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain PIP5K PF01504.18 CAR28038.1 - 0.01 15.1 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase AAA PF00004.29 CAR28038.1 - 0.038 14.4 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CAR28038.1 - 0.045 14.1 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DUF366 PF04017.12 CAR28038.1 - 0.12 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF366) TsaE PF02367.17 CAR28038.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mak10 PF04112.13 CAR28039.1 - 5.1e-43 146.5 0.0 1e-42 145.5 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase MapZ_EC1 PF18041.1 CAR28039.1 - 0.072 13.3 5.9 0.21 11.8 1.9 2.8 2 0 0 2 2 2 0 MapZ extracellular domain 1 DUF2489 PF10675.9 CAR28039.1 - 0.12 12.3 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Ribosomal_L11_N PF03946.14 CAR28040.1 - 2.6e-21 75.2 0.9 4.1e-21 74.6 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CAR28040.1 - 6.2e-15 55.5 0.9 8.4e-15 55.0 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain IMS PF00817.20 CAR28041.1 - 9.9e-43 145.7 0.0 1.5e-42 145.2 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CAR28041.1 - 9e-06 26.4 0.1 3.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CAR28041.1 - 0.024 15.0 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 IMS family HHH motif zf_UBZ PF18439.1 CAR28041.1 - 0.044 13.4 1.6 0.26 10.9 0.2 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger TMEM223 PF14640.6 CAR28042.1 - 0.15 12.2 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 Transmembrane protein 223 Zn_clus PF00172.18 CAR28043.1 - 4.3e-08 33.2 10.2 7.9e-08 32.3 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMPKBI PF04739.15 CAR28045.1 - 1.5e-19 70.0 0.3 6e-19 68.1 0.0 2.2 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CAR28045.1 - 4.2e-08 33.3 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase PAP1 PF08601.10 CAR28046.1 - 1.6e-20 74.2 34.9 3e-17 63.4 1.8 3.3 3 0 0 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.21 CAR28046.1 - 1.7e-09 37.6 8.5 4.4e-09 36.3 8.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CAR28046.1 - 1.3e-06 28.4 8.1 3.3e-06 27.1 8.1 1.7 1 0 0 1 1 1 1 Basic region leucine zipper MscS_TM PF12794.7 CAR28046.1 - 1.3 7.8 3.3 2 7.2 3.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 YabA PF06156.13 CAR28046.1 - 2.1 9.0 6.3 6.7 7.4 6.3 1.8 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_Maf PF03131.17 CAR28046.1 - 5.5 7.6 11.9 0.69 10.5 7.1 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Sterol_MT_C PF08498.10 CAR28047.1 - 1.9e-25 89.0 1.4 3.1e-25 88.3 1.4 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CAR28047.1 - 9.4e-21 74.3 0.0 1.8e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR28047.1 - 8.5e-18 64.9 0.0 1.9e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR28047.1 - 5.9e-17 61.9 0.0 9.3e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR28047.1 - 1.1e-13 51.3 0.0 1.6e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CAR28047.1 - 2.1e-12 46.9 0.3 2.9e-12 46.5 0.3 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CAR28047.1 - 2.1e-10 41.2 0.1 5.1e-10 40.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR28047.1 - 2.9e-10 39.9 0.0 4.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 CAR28047.1 - 1.6e-05 24.5 0.3 3.4e-05 23.5 0.3 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 CAR28047.1 - 7.2e-05 22.3 0.0 0.00015 21.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CAR28047.1 - 0.00051 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CAR28047.1 - 0.013 15.1 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 CAR28047.1 - 0.022 14.8 0.2 0.043 13.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 CAR28047.1 - 0.034 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RrnaAD PF00398.20 CAR28047.1 - 0.038 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 CAR28047.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.18 CAR28047.1 - 0.085 12.5 0.2 0.24 11.1 0.2 1.7 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PDZ_6 PF17820.1 CAR28047.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 PDZ domain Sugar_tr PF00083.24 CAR28048.1 - 1.1e-31 110.2 37.2 4e-20 72.1 13.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CAR28048.1 - 5.2e-18 65.1 67.6 1.8e-14 53.5 42.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.23 CAR28049.1 - 8.6e-101 337.2 1.6 8.6e-101 337.2 1.6 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CAR28049.1 - 1.6e-24 86.6 1.5 4e-24 85.3 0.1 2.3 2 0 0 2 2 2 1 Microtubule binding Transposase_1 PF01359.18 CAR28049.1 - 0.061 13.2 0.4 0.17 11.7 0.4 1.7 1 0 0 1 1 1 0 Transposase (partial DDE domain) Desmo_N PF06771.11 CAR28049.1 - 0.87 10.0 3.2 0.74 10.2 0.3 2.4 2 1 1 3 3 3 0 Viral Desmoplakin N-terminus DUF4606 PF15379.6 CAR28049.1 - 1.1 9.6 8.8 0.059 13.6 3.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) Dynein_light PF01221.18 CAR28050.1 - 7.6e-32 109.5 0.1 8.3e-32 109.4 0.1 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 CAR28050.1 - 0.14 12.9 0.0 0.17 12.6 0.0 1.3 1 0 0 1 1 1 0 Ground-like domain PX PF00787.24 CAR28051.1 - 4.4e-15 55.6 0.2 1.7e-14 53.8 0.2 2.0 1 0 0 1 1 1 1 PX domain DUF19 PF01579.18 CAR28051.1 - 0.013 15.3 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF19) PilO PF04350.13 CAR28051.1 - 6.2 7.0 9.3 1.7 8.8 1.8 3.1 3 0 0 3 3 3 0 Pilus assembly protein, PilO Katanin_con80 PF13925.6 CAR28051.1 - 6.9 6.7 7.8 13 5.8 1.8 2.5 2 0 0 2 2 2 0 con80 domain of Katanin Rpn9_C PF18261.1 CAR28052.1 - 2.1e-16 59.2 0.9 4.4e-16 58.2 0.9 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix PCI PF01399.27 CAR28052.1 - 1.7e-13 51.0 0.0 5.7e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 PCI domain ELF PF03317.13 CAR28052.1 - 0.0056 16.7 0.3 0.012 15.6 0.3 1.5 1 0 0 1 1 1 1 ELF protein Abhydrolase_3 PF07859.13 CAR28053.1 - 1.9e-11 44.2 0.0 2.2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR28053.1 - 0.00057 20.5 0.0 0.00063 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CAR28053.1 - 0.0025 18.0 0.0 0.0036 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 CAR28053.1 - 0.0085 15.4 0.0 0.74 9.0 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 CAR28053.1 - 0.02 14.4 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 CAR28053.1 - 0.025 14.5 0.0 0.078 12.8 0.0 1.8 1 1 1 2 2 2 0 Lipase (class 3) Abhydrolase_1 PF00561.20 CAR28053.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 CAR28053.1 - 0.14 11.7 0.0 0.41 10.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) eIF3g PF12353.8 CAR28054.1 - 8.3e-41 139.3 2.2 1.2e-40 138.8 2.2 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CAR28054.1 - 7.4e-11 41.7 0.0 1.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_6 PF18585.1 CAR28054.1 - 0.26 11.2 0.7 0.84 9.6 0.4 1.9 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Ribosomal_L33 PF00471.20 CAR28055.1 - 0.0022 18.4 0.0 0.0071 16.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L33 Spt5_N PF11942.8 CAR28056.1 - 4.2e-21 75.8 14.6 4.2e-21 75.8 14.6 4.4 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 CAR28056.1 - 2.1e-20 72.4 0.0 4.3e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CAR28056.1 - 6.4e-16 57.7 16.1 0.00042 20.2 0.4 4.6 4 0 0 4 4 4 4 KOW motif DUF3912 PF13051.6 CAR28056.1 - 0.0061 16.8 0.9 0.94 9.8 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3912) DUF4438 PF14505.6 CAR28056.1 - 0.013 14.5 0.1 0.41 9.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4438) Myosin_N PF02736.19 CAR28056.1 - 0.17 11.7 1.4 7.5 6.5 0.1 3.1 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Rad33 PF08730.10 CAR28057.1 - 3.4e-13 49.9 2.7 7.6e-07 29.3 0.1 2.1 1 1 1 2 2 2 2 Rad33 Sigma_reg_C PF13791.6 CAR28057.1 - 0.096 12.9 0.1 0.14 12.4 0.1 1.4 1 1 0 1 1 1 0 Sigma factor regulator C-terminal EMP24_GP25L PF01105.24 CAR28058.1 - 9.7e-43 146.2 0.0 1.1e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 CAR28058.1 - 0.0051 15.1 0.3 0.0064 14.7 0.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA M16C_assoc PF08367.11 CAR28059.1 - 3.1e-75 252.5 0.0 5.2e-75 251.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CAR28059.1 - 9.2e-30 104.0 0.0 8.5e-21 74.8 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CAR28059.1 - 2.5e-07 30.8 0.0 8.1e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) RRM_1 PF00076.22 CAR28060.1 - 5.2e-30 103.1 0.4 2.6e-17 62.4 0.3 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR28060.1 - 0.0036 17.1 0.0 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CAR28060.1 - 0.007 16.0 0.0 0.026 14.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CAR28060.1 - 0.042 13.9 0.0 7 6.8 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 RRM_7 PF16367.5 CAR28060.1 - 0.069 13.3 0.1 0.47 10.6 0.0 2.1 1 1 1 2 2 2 0 RNA recognition motif UBX PF00789.20 CAR28061.1 - 3.4e-11 43.2 0.1 1.1e-09 38.4 0.0 3.0 2 1 0 2 2 2 1 UBX domain UBA_4 PF14555.6 CAR28061.1 - 2.4e-10 40.1 0.0 1.4e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 UBA-like domain Methyltransf_11 PF08241.12 CAR28062.1 - 3e-12 47.0 0.0 7.1e-12 45.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR28062.1 - 2.2e-10 41.1 0.0 4.9e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR28062.1 - 1.7e-06 28.7 0.3 1e-05 26.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR28062.1 - 1.8e-06 27.8 0.0 3.5e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR28062.1 - 1.4e-05 25.0 0.1 5.3e-05 23.1 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain M16C_assoc PF08367.11 CAR28062.1 - 0.66 9.0 3.5 0.89 8.6 3.5 1.2 1 0 0 1 1 1 0 Peptidase M16C associated PIG-S PF10510.9 CAR28063.1 - 1.8e-135 452.7 2.2 2.1e-135 452.5 2.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TAFII28 PF04719.14 CAR28064.1 - 5.9e-27 93.6 1.8 1.3e-23 82.8 1.3 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region DUF2986 PF11661.8 CAR28064.1 - 0.37 11.4 3.5 0.8 10.3 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) LCM PF04072.14 CAR28065.1 - 2.7e-19 69.8 0.0 3.3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Metallophos PF00149.28 CAR28066.1 - 4.7e-36 125.2 0.1 1e-35 124.1 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAR28066.1 - 1.9e-18 66.6 0.1 3.7e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain PIG-P PF08510.12 CAR28067.1 - 1.9e-32 111.7 2.7 2.2e-32 111.5 2.7 1.0 1 0 0 1 1 1 1 PIG-P EamA PF00892.20 CAR28069.1 - 1.3e-13 51.3 33.6 1.5e-08 34.9 15.3 3.1 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 CAR28069.1 - 5e-05 22.8 14.8 0.00013 21.5 14.8 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family DUF3955 PF13127.6 CAR28069.1 - 0.0015 18.3 1.7 0.0015 18.3 1.7 4.9 6 0 0 6 6 6 1 Protein of unknown function (DUF3955) Phage_holin_2_4 PF16082.5 CAR28069.1 - 0.06 13.1 1.2 4.5 7.1 1.2 2.8 1 1 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DUF3094 PF11293.8 CAR28069.1 - 1.1 9.0 8.4 0.29 10.9 4.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) OST3_OST6 PF04756.13 CAR28070.1 - 6.3e-67 226.0 1.2 7.3e-67 225.8 1.2 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 CAR28070.1 - 0.027 14.4 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin LRS4 PF10422.9 CAR28071.1 - 1.2e-25 90.6 9.9 1.5e-25 90.2 8.3 1.9 1 1 0 1 1 1 1 Monopolin complex subunit LRS4 Serglycin PF04360.12 CAR28071.1 - 0.00015 21.7 1.9 0.00025 21.0 1.9 1.4 1 0 0 1 1 1 1 Serglycin FlxA PF14282.6 CAR28071.1 - 0.00019 21.3 9.4 0.00019 21.3 9.4 2.2 2 0 0 2 2 2 1 FlxA-like protein Apt1 PF10351.9 CAR28071.1 - 0.036 12.9 3.2 0.061 12.2 3.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Med15_fungi PF05397.12 CAR28071.1 - 0.15 12.4 4.2 0.26 11.6 4.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 15 DUF3450 PF11932.8 CAR28071.1 - 0.52 9.6 5.9 0.98 8.7 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) EMC3_TMCO1 PF01956.16 CAR28071.1 - 2.8 7.6 5.0 0.45 10.2 1.5 1.5 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like TPR_MLP1_2 PF07926.12 CAR28071.1 - 3 7.9 16.5 0.24 11.5 9.3 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Secretin_N_2 PF07655.13 CAR28071.1 - 5.7 7.5 12.7 0.21 12.2 5.9 2.1 3 0 0 3 3 3 0 Secretin N-terminal domain OmpH PF03938.14 CAR28071.1 - 5.8 7.3 11.4 2.2 8.6 5.3 2.5 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF5320 PF17253.2 CAR28071.1 - 6.9 7.8 11.3 3.1 8.9 5.9 2.7 2 2 1 3 3 3 0 Family of unknown function (DUF5320) UDG PF03167.19 CAR28073.1 - 2.5e-23 82.8 0.0 4.1e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DOT1 PF08123.13 CAR28074.1 - 1.1e-86 289.6 0.0 1.7e-86 289.0 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Pribosyltran PF00156.27 CAR28075.1 - 1.2e-14 54.1 0.0 1.7e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CAR28075.1 - 0.0047 16.4 0.0 0.0065 15.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase MoCF_biosynth PF00994.24 CAR28075.1 - 0.024 14.3 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Probable molybdopterin binding domain PRTase_2 PF15609.6 CAR28075.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase Nse5 PF08691.10 CAR28076.1 - 3.4e-164 547.3 12.2 3.9e-164 547.1 12.2 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Med13_N PF11597.8 CAR28077.1 - 8.6e-72 242.2 0.2 8.6e-72 242.2 0.2 2.0 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 CAR28077.1 - 1.5e-22 80.4 6.4 2.6e-17 63.1 0.1 3.2 2 2 2 4 4 4 2 Mediator complex subunit 13 C-terminal domain GSHPx PF00255.19 CAR28078.1 - 4.9e-49 164.4 0.4 6.2e-49 164.1 0.4 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CAR28078.1 - 9.4e-05 22.3 0.0 0.00026 20.9 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAR28078.1 - 0.00012 21.8 0.0 0.0004 20.1 0.0 1.8 1 1 0 1 1 1 1 Redoxin Sugar_tr PF00083.24 CAR28079.1 - 2.1e-158 527.9 23.8 2.5e-158 527.7 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR28079.1 - 1.6e-37 129.2 27.5 1.7e-34 119.4 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.20 CAR28079.1 - 0.073 12.7 3.2 0.73 9.4 1.5 3.2 3 1 0 3 3 3 0 Prokaryotic cytochrome b561 COX7C PF02935.16 CAR28079.1 - 0.3 11.4 0.1 0.3 11.4 0.1 3.2 4 0 0 4 4 4 0 Cytochrome c oxidase subunit VIIc OPT PF03169.15 CAR28080.1 - 5e-152 507.7 42.1 5.8e-152 507.5 42.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF676 PF05057.14 CAR28081.1 - 7.4e-49 166.2 0.0 1.2e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CAR28081.1 - 0.001 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.11 CAR28081.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 CAR28081.1 - 0.12 12.0 0.0 0.89 9.1 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold LCAT PF02450.15 CAR28081.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase FAD-oxidase_C PF02913.19 CAR28082.1 - 2.8e-50 171.3 0.0 3.7e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CAR28082.1 - 2.8e-32 111.3 0.0 6.6e-32 110.1 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain ECM11 PF15463.6 CAR28083.1 - 2.7e-19 70.1 3.6 1.1e-18 68.1 3.3 2.2 1 1 0 1 1 1 1 Extracellular mutant protein 11 BLOC1_2 PF10046.9 CAR28083.1 - 0.027 14.7 0.6 0.28 11.5 0.1 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_S17e PF00833.18 CAR28084.1 - 8.9e-55 183.8 0.4 1.1e-54 183.6 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 PemK_toxin PF02452.17 CAR28084.1 - 0.051 14.0 0.1 0.087 13.2 0.1 1.4 1 0 0 1 1 1 0 PemK-like, MazF-like toxin of type II toxin-antitoxin system ZZ PF00569.17 CAR28085.1 - 1.3e-13 50.5 8.0 2.5e-13 49.6 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CAR28085.1 - 4.7e-08 33.1 0.0 9.9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 CAR28085.1 - 2.9e-07 30.7 0.0 2.9e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 CAR28085.1 - 0.0011 19.1 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Baculo_IE-1 PF05290.11 CAR28085.1 - 1.7 8.6 5.2 3.4 7.6 5.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) U3_assoc_6 PF08640.11 CAR28086.1 - 2.5e-31 107.6 4.0 1.8e-29 101.6 0.6 2.6 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 CAR28086.1 - 0.00071 18.8 6.1 0.0019 17.4 1.6 2.6 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CAR28086.1 - 0.00082 20.0 0.0 0.091 13.6 0.0 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat Suf PF05843.14 CAR28086.1 - 0.011 15.8 10.2 0.12 12.4 7.1 3.6 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) ARL2_Bind_BART PF11527.8 CAR28086.1 - 0.017 15.2 3.6 0.22 11.6 0.4 3.1 2 1 0 2 2 2 0 The ARF-like 2 binding protein BART DUF2250 PF10007.9 CAR28086.1 - 0.035 14.2 0.1 1.7 8.8 0.1 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) TPR_17 PF13431.6 CAR28086.1 - 0.12 12.8 1.0 1.1 9.8 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.16 CAR28086.1 - 0.37 10.8 2.2 0.63 10.0 0.3 2.4 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat Ribosomal_L4 PF00573.22 CAR28087.1 - 2.4e-50 170.9 0.0 2.8e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S13 PF00416.22 CAR28088.1 - 8e-56 187.9 2.6 9.1e-56 187.7 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CAR28088.1 - 0.0032 16.3 0.0 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 CAR28088.1 - 0.079 13.2 0.2 0.32 11.3 0.1 2.0 1 1 0 1 1 1 0 Helix-hairpin-helix motif BET PF17035.5 CAR28088.1 - 0.11 12.6 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Bromodomain extra-terminal - transcription regulation PP28 PF10252.9 CAR28088.1 - 0.29 11.6 1.8 0.31 11.5 0.4 1.7 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Homeodomain PF00046.29 CAR28089.1 - 7.6e-18 64.1 7.5 3.4e-17 62.0 6.3 2.3 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 CAR28089.1 - 0.0054 16.6 3.3 0.0054 16.6 3.3 3.2 2 2 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 CAR28089.1 - 0.097 12.5 0.2 0.21 11.4 0.2 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Metallophos PF00149.28 CAR28090.1 - 6.6e-07 30.0 0.7 1.8e-06 28.6 0.1 2.1 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase DUF4710 PF15828.5 CAR28090.1 - 1.2 9.3 6.3 3.4 7.9 6.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) AhpC-TSA PF00578.21 CAR28091.1 - 5.5e-36 123.2 0.0 9.2e-36 122.5 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CAR28091.1 - 7.8e-20 71.1 0.1 1.3e-19 70.4 0.0 1.4 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 CAR28091.1 - 3.1e-07 30.1 0.1 5.7e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CAR28091.1 - 0.052 13.5 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 SCO1/SenC ubiquitin PF00240.23 CAR28092.1 - 0.00092 18.9 0.0 0.0031 17.2 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CAR28092.1 - 0.016 15.3 0.0 0.016 15.3 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like DUF4834 PF16118.5 CAR28092.1 - 0.17 12.9 7.0 15 6.6 4.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) HIG_1_N PF04588.13 CAR28093.1 - 1.8e-16 60.1 1.5 2.7e-16 59.5 1.5 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF4407 PF14362.6 CAR28093.1 - 0.0085 15.5 4.1 0.015 14.7 4.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) CD20 PF04103.15 CAR28093.1 - 0.013 15.6 0.0 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 CD20-like family DUF2514 PF10721.9 CAR28093.1 - 0.023 14.7 5.3 0.086 12.9 5.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) DUF3084 PF11283.8 CAR28093.1 - 0.085 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3084) DUF1003 PF06210.11 CAR28093.1 - 7.7 6.7 6.5 5.5 7.1 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1003) Guanylate_kin PF00625.21 CAR28094.1 - 6.7e-67 224.7 0.0 7.6e-67 224.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 CAR28094.1 - 3.8e-06 27.4 0.0 6.3e-06 26.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CAR28094.1 - 6.8e-05 23.1 0.0 0.00049 20.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CAR28094.1 - 0.00019 21.8 0.0 0.002 18.5 0.0 2.1 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 CAR28094.1 - 0.00085 19.4 0.0 0.0014 18.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CAR28094.1 - 0.00086 19.9 0.0 0.002 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CAR28094.1 - 0.0014 18.9 0.0 0.0031 17.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAR28094.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CAR28094.1 - 0.0015 18.1 0.0 0.0055 16.2 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CAR28094.1 - 0.002 18.1 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 CAR28094.1 - 0.0049 17.3 0.1 0.012 16.0 0.0 1.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CAR28094.1 - 0.0068 16.9 0.0 0.015 15.8 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 CAR28094.1 - 0.0078 15.9 1.0 0.047 13.4 0.2 2.3 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CAR28094.1 - 0.016 14.9 0.0 0.03 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 CAR28094.1 - 0.016 14.2 0.0 0.037 13.1 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 CAR28094.1 - 0.022 14.8 0.0 0.046 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR28094.1 - 0.034 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 CAR28094.1 - 0.041 13.6 0.1 0.054 13.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CAR28094.1 - 0.061 13.3 0.1 0.39 10.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 CAR28094.1 - 0.088 12.7 0.1 0.13 12.1 0.1 1.5 1 1 0 1 1 1 0 NTPase Rad17 PF03215.15 CAR28094.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain TsaE PF02367.17 CAR28094.1 - 0.14 12.1 0.1 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Na_H_Exchanger PF00999.21 CAR28095.1 - 2.9e-66 223.8 39.4 3.7e-66 223.5 39.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.6 CAR28095.1 - 0.058 13.3 2.2 0.26 11.2 1.1 2.2 2 0 0 2 2 2 0 Myc target protein 1 Ndc1_Nup PF09531.10 CAR28096.1 - 2.2e-106 357.0 15.5 3.2e-106 356.4 15.5 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Rad52_Rad22 PF04098.15 CAR28097.1 - 2.5e-55 186.6 0.0 3.6e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PHtD_u1 PF16645.5 CAR28097.1 - 3.2 8.2 8.7 0.73 10.3 2.7 2.5 2 0 0 2 2 2 0 Unstructured region on Pneumococcal histidine triad protein HECT PF00632.25 CAR28098.1 - 2e-90 303.4 1.9 8.7e-90 301.3 0.1 2.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 CAR28098.1 - 1.7e-57 195.5 4.0 3.9e-57 194.3 0.3 3.0 2 1 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 CAR28098.1 - 2.4e-52 178.1 0.0 2.4e-52 178.1 0.0 3.2 4 0 0 4 4 4 2 Domain of Unknown Function (DUF913) UBM PF14377.6 CAR28098.1 - 1.2e-17 62.7 10.3 1.7e-10 40.0 0.3 3.1 3 0 0 3 3 3 2 Ubiquitin binding region MSC PF09402.10 CAR28099.1 - 7.1e-108 361.1 0.6 7.1e-108 361.1 0.6 1.8 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain HeH PF12949.7 CAR28099.1 - 3e-18 65.2 0.1 7.4e-18 64.0 0.1 1.7 1 0 0 1 1 1 1 HeH/LEM domain Rhabdo_ncap PF00945.18 CAR28099.1 - 0.082 11.8 4.2 0.022 13.7 1.1 1.6 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein DUF728 PF05304.12 CAR28099.1 - 2.6 7.9 5.2 0.38 10.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF728) A_deaminase PF00962.22 CAR28100.1 - 6.5e-128 426.7 0.1 8.5e-128 426.3 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DHHC PF01529.20 CAR28101.1 - 1.8e-24 86.4 6.5 1.8e-24 86.4 6.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase Promethin PF16015.5 CAR28101.1 - 2.5 8.0 11.3 3.8 7.5 2.0 2.5 2 0 0 2 2 2 0 Promethin MAT1 PF06391.13 CAR28102.1 - 3.7e-65 219.6 21.1 4.8e-65 219.2 21.1 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 CAR28102.1 - 3.3e-27 94.1 7.6 6.2e-27 93.2 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR28102.1 - 0.00029 20.6 4.4 0.00058 19.6 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR28102.1 - 0.0011 19.2 6.3 0.002 18.4 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CAR28102.1 - 0.0016 18.3 2.7 0.0044 16.9 2.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAR28102.1 - 0.0047 16.8 5.4 0.0082 16.0 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FliS PF02561.14 CAR28102.1 - 0.0069 16.6 8.4 0.099 12.9 2.5 2.2 1 1 1 2 2 2 2 Flagellar protein FliS zf-RING_UBOX PF13445.6 CAR28102.1 - 0.04 13.9 6.5 0.082 12.9 6.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CAR28102.1 - 0.07 13.1 6.8 0.18 11.8 6.8 1.7 1 1 0 1 1 1 0 zinc-RING finger domain UPF0160 PF03690.13 CAR28102.1 - 0.077 12.6 3.7 0.1 12.2 3.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Zn_ribbon_17 PF17120.5 CAR28102.1 - 0.17 11.5 1.5 0.32 10.7 1.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Spectrin PF00435.21 CAR28102.1 - 0.34 11.4 11.1 1 9.9 9.4 2.4 1 1 1 2 2 2 0 Spectrin repeat zf-RING_4 PF14570.6 CAR28102.1 - 0.93 9.3 7.8 2.6 7.9 7.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Mitovir_RNA_pol PF05919.11 CAR28102.1 - 1.1 8.4 5.3 1.3 8.1 5.3 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase CGI-121 PF08617.10 CAR28103.1 - 1.9e-40 138.6 1.5 2.4e-40 138.3 1.5 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 MRP-L28 PF09812.9 CAR28105.1 - 1.5e-31 109.8 3.6 1.7e-31 109.5 3.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 FYRC PF05965.14 CAR28105.1 - 0.092 12.9 0.2 0.21 11.7 0.1 1.7 2 0 0 2 2 2 0 F/Y rich C-terminus DUF4093 PF13331.6 CAR28105.1 - 0.13 12.7 0.3 0.18 12.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) TPT PF03151.16 CAR28106.1 - 7.7e-15 55.0 13.0 1.2e-07 31.4 6.1 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.11 CAR28106.1 - 1.5e-07 31.0 10.7 1.5e-06 27.7 1.1 2.1 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.20 CAR28106.1 - 4.2e-06 27.0 24.1 0.0007 19.8 7.6 3.6 3 1 0 3 3 3 2 EamA-like transporter family Ni_hydr_CYTB PF01292.20 CAR28106.1 - 0.00013 21.6 4.3 0.51 9.9 0.1 3.2 2 1 1 3 3 3 3 Prokaryotic cytochrome b561 TMEM234 PF10639.9 CAR28106.1 - 0.062 13.3 6.0 1.7 8.7 0.2 2.9 3 0 0 3 3 3 0 Putative transmembrane family 234 EmrE PF13536.6 CAR28106.1 - 0.075 12.6 6.5 0.45 10.1 1.6 2.6 2 1 0 2 2 2 0 Putative multidrug resistance efflux transporter DUF485 PF04341.12 CAR28106.1 - 2.6 8.1 11.3 0.66 10.0 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function, DUF485 zf-C2H2 PF00096.26 CAR28107.1 - 3.8e-05 23.9 14.9 0.00079 19.8 2.9 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR28107.1 - 0.00013 22.5 11.6 0.043 14.7 1.5 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CAR28107.1 - 0.087 13.5 0.1 1.8 9.2 0.0 2.7 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats PriA_CRR PF18319.1 CAR28107.1 - 0.11 12.5 0.5 1 9.4 0.1 2.6 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain zf-H2C2_2 PF13465.6 CAR28107.1 - 0.35 11.4 13.3 0.13 12.7 1.0 3.8 4 0 0 4 4 4 0 Zinc-finger double domain Zn_ribbon_recom PF13408.6 CAR28107.1 - 2.1 9.0 4.6 3.8 8.1 0.9 2.5 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF3020 PF11223.8 CAR28108.1 - 3e-19 69.3 14.1 3e-19 69.3 14.1 9.1 8 1 0 8 8 8 2 Protein of unknown function (DUF3020) p450 PF00067.22 CAR28109.1 - 3.4e-102 342.6 0.0 3.9e-102 342.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 CAR28110.1 - 1.2e-06 28.5 11.4 2.6e-06 27.4 11.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CAR28110.1 - 1.9e-05 23.9 0.3 9.4e-05 21.6 0.1 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR28111.1 - 2.9e-09 36.9 8.1 9.3e-09 35.3 8.1 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_H_Exchanger PF00999.21 CAR28112.1 - 9.9e-97 324.1 20.4 1.2e-96 323.9 20.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 CAR28112.1 - 2.3e-30 106.3 11.3 3e-30 105.9 11.3 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus DcpS PF05652.12 CAR28113.1 - 4.4e-36 123.9 0.0 7e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 CAR28113.1 - 2.2e-34 118.3 0.1 1.7e-33 115.5 0.0 2.1 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DUF4187 PF13821.6 CAR28114.1 - 1.4e-16 60.0 4.2 3.1e-16 58.9 4.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 CAR28114.1 - 0.00017 21.4 0.1 0.00032 20.5 0.1 1.4 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 CAR28114.1 - 0.075 13.3 0.5 0.15 12.4 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Med4 PF10018.9 CAR28115.1 - 1.3e-37 129.4 0.6 1.3e-37 129.4 0.6 1.5 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 TraB PF01963.17 CAR28115.1 - 0.021 14.7 0.3 0.03 14.2 0.3 1.1 1 0 0 1 1 1 0 TraB family Baculo_PEP_C PF04513.12 CAR28115.1 - 0.022 14.8 0.1 0.032 14.3 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF244 PF03112.14 CAR28115.1 - 0.042 13.7 1.1 0.12 12.2 1.1 1.8 1 1 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Sec34 PF04136.15 CAR28115.1 - 0.065 13.1 2.6 0.13 12.1 2.6 1.6 1 1 0 1 1 1 0 Sec34-like family NPV_P10 PF05531.12 CAR28115.1 - 0.17 12.4 0.7 1.5 9.4 0.7 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DASH_Dad3 PF08656.10 CAR28115.1 - 0.24 11.5 2.2 0.43 10.7 0.3 2.3 3 0 0 3 3 3 0 DASH complex subunit Dad3 MBOAT PF03062.19 CAR28116.1 - 1.8e-66 224.9 14.9 1.8e-66 224.9 14.9 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ferrochelatase PF00762.19 CAR28117.1 - 1.4e-94 316.8 0.0 1.6e-94 316.6 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Cnd1 PF12717.7 CAR28118.1 - 5.4e-52 176.1 11.4 1.7e-45 154.9 0.1 3.9 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CAR28118.1 - 1.3e-45 155.2 4.5 2.2e-45 154.5 1.6 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 CAR28118.1 - 4.1e-10 39.0 3.1 1 9.8 0.0 5.7 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.6 CAR28118.1 - 1.1e-07 32.1 0.0 0.017 15.5 0.0 3.6 2 1 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.6 CAR28118.1 - 1.1e-05 25.8 0.4 20 5.8 0.0 5.0 4 0 0 4 4 4 2 HEAT-like repeat Cnd3 PF12719.7 CAR28118.1 - 0.00066 19.0 0.2 0.00066 19.0 0.2 3.3 2 2 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain YtzH PF14165.6 CAR28118.1 - 0.065 13.6 3.9 3.9 7.9 0.2 3.4 3 0 0 3 3 3 0 YtzH-like protein CBM_21 PF03370.13 CAR28119.1 - 3.3e-26 91.7 3.9 8e-26 90.4 3.9 1.7 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CAR28119.1 - 3.5e-05 24.3 5.4 0.00031 21.3 5.4 2.5 1 1 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) FAM176 PF14851.6 CAR28119.1 - 1.3 8.7 6.1 14 5.3 0.1 2.6 2 0 0 2 2 2 0 FAM176 family MCM PF00493.23 CAR28120.1 - 6.1e-103 342.7 0.0 9.7e-103 342.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR28120.1 - 1.4e-36 125.2 0.5 2.9e-36 124.1 0.1 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 CAR28120.1 - 8.7e-29 99.8 1.8 3e-28 98.1 1.8 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CAR28120.1 - 1.4e-16 61.0 0.3 3.4e-16 59.7 0.3 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAR28120.1 - 2.4e-06 27.1 0.0 0.00058 19.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CAR28120.1 - 1.4e-05 25.1 0.0 4.9e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CAR28120.1 - 0.0016 18.3 0.1 0.0061 16.4 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Imm35 PF15567.6 CAR28120.1 - 0.0093 16.1 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 1 Immunity protein 35 Sigma54_activat PF00158.26 CAR28120.1 - 0.051 13.3 0.0 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF1822 PF08852.11 CAR28120.1 - 0.06 12.4 0.5 4.1 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) LSM PF01423.22 CAR28121.1 - 6e-18 64.3 0.6 8.5e-18 63.8 0.6 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CAR28121.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Hfq protein DEAD PF00270.29 CAR28122.1 - 1.6e-39 135.5 2.1 3e-39 134.6 2.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR28122.1 - 2.7e-31 108.2 1.0 1.2e-30 106.1 0.1 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR28122.1 - 1.4e-07 31.7 2.4 2.3e-07 31.0 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1601 PF07671.11 CAR28122.1 - 0.069 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) DnaI_N PF07319.11 CAR28122.1 - 0.39 11.4 5.0 14 6.4 0.4 3.2 2 1 0 2 2 2 0 Primosomal protein DnaI N-terminus CPSF73-100_C PF11718.8 CAR28123.1 - 1.3e-57 194.8 5.1 2.2e-57 194.1 5.1 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CAR28123.1 - 1.6e-29 102.4 0.0 4.1e-29 101.1 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 CAR28123.1 - 6.2e-22 78.6 0.7 1e-21 77.8 0.7 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CAR28123.1 - 1.7e-21 76.5 0.0 3.8e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CAR28123.1 - 3.6e-18 65.3 0.0 7.3e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CAR28123.1 - 4.3e-07 29.7 0.2 4.2e-06 26.4 0.3 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CAR28123.1 - 7.4e-05 22.7 0.0 0.00027 20.9 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Fungal_trans PF04082.18 CAR28124.1 - 1.4e-18 66.9 1.1 3.2e-18 65.7 1.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR28124.1 - 1.4e-05 25.1 12.6 1.4e-05 25.1 12.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH_1 PF00378.20 CAR28125.1 - 1.8e-28 99.6 0.0 2.3e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAR28125.1 - 5.4e-14 52.4 0.0 9.5e-14 51.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RF-1 PF00472.20 CAR28126.1 - 3.3e-19 68.9 8.5 5.2e-19 68.3 8.5 1.4 1 0 0 1 1 1 1 RF-1 domain Peptidase_S49_N PF08496.10 CAR28126.1 - 2.2 8.3 8.2 3 7.9 8.2 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1640 PF07798.11 CAR28127.1 - 2.4e-24 86.3 4.0 2.4e-24 86.3 4.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) ECH_1 PF00378.20 CAR28128.1 - 1.1e-12 47.9 0.0 1.6e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CAR28128.1 - 9.3e-08 31.9 0.0 1.1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Init_tRNA_PT PF04179.12 CAR28128.1 - 0.029 14.7 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Methyltransf_16 PF10294.9 CAR28129.1 - 1.5e-15 57.3 0.0 2e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CAR28129.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR28129.1 - 0.011 16.5 0.0 0.021 15.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_18 PF00704.28 CAR28130.1 - 1.2e-25 90.9 1.0 3.1e-25 89.6 1.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 CAR28130.1 - 3.2e-05 23.8 11.0 3.2e-05 23.8 11.0 6.1 2 1 4 6 6 6 1 Carbohydrate binding domain (family 19) WH1 PF00568.23 CAR28131.1 - 5.7e-32 110.0 0.0 7.8e-32 109.5 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CAR28131.1 - 9.8e-05 22.1 1.2 0.0002 21.1 1.2 1.5 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.19 CAR28131.1 - 0.00011 21.8 4.5 0.00011 21.8 4.5 9.8 1 1 6 7 7 7 2 Adenylate cyclase associated (CAP) N terminal GCIP PF13324.6 CAR28132.1 - 2.6e-44 151.8 3.4 3.6e-44 151.3 3.4 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting XPC-binding PF09280.11 CAR28132.1 - 0.017 14.8 0.0 0.066 13.0 0.0 2.0 1 0 0 1 1 1 0 XPC-binding domain DUF713 PF05218.14 CAR28132.1 - 3.6 7.3 11.3 1 9.1 3.3 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF713) Ribosomal_S30 PF04758.14 CAR28133.1 - 6e-28 96.8 5.5 6.7e-28 96.7 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Aminotran_5 PF00266.19 CAR28134.1 - 1.2e-38 133.1 0.0 1.5e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V UPF0113_N PF17833.1 CAR28134.1 - 0.12 12.9 0.0 0.38 11.4 0.0 1.8 1 0 0 1 1 1 0 UPF0113 Pre-PUA domain Hus1 PF04005.12 CAR28135.1 - 1.3e-26 93.4 0.1 2.2e-25 89.4 0.1 2.0 1 1 0 1 1 1 1 Hus1-like protein DUF3274 PF11678.8 CAR28135.1 - 0.13 11.5 1.2 0.2 10.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) GTP_EFTU PF00009.27 CAR28136.1 - 1.7e-49 168.0 0.0 2.7e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CAR28136.1 - 9.7e-42 141.5 7.7 2.1e-41 140.4 7.7 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CAR28136.1 - 2.3e-18 66.0 0.0 4.2e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CAR28136.1 - 4.5e-08 33.4 1.2 1.2e-07 32.1 1.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAR28136.1 - 5.6e-06 26.4 0.5 6.4e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 CAR28136.1 - 0.0015 18.1 0.0 0.0039 16.8 0.0 1.6 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CAR28136.1 - 0.0052 16.2 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 CAR28136.1 - 0.0057 16.5 0.1 0.023 14.5 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 CAR28136.1 - 0.0079 16.3 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II NAD_binding_10 PF13460.6 CAR28137.1 - 8.1e-06 25.9 0.0 8.7e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CAR28137.1 - 0.00032 19.8 0.0 0.00082 18.5 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CAR28137.1 - 0.00097 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CAR28137.1 - 0.028 13.6 0.0 0.24 10.5 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 CAR28137.1 - 0.042 12.9 0.0 0.089 11.9 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain IF-2B PF01008.17 CAR28138.1 - 1.9e-85 286.5 0.5 5.3e-85 285.0 0.5 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family HeLo PF14479.6 CAR28138.1 - 0.5 10.2 5.4 1.4 8.7 5.5 1.6 1 1 0 1 1 1 0 Prion-inhibition and propagation TPR_1 PF00515.28 CAR28139.1 - 0.0046 16.7 0.1 0.68 9.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAR28139.1 - 0.0074 17.0 0.4 0.14 13.1 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAR28139.1 - 0.008 16.2 0.0 3.4 8.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_6 PF12774.7 CAR28139.1 - 0.11 11.4 0.2 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TPR_19 PF14559.6 CAR28139.1 - 0.15 12.6 2.7 0.17 12.4 0.2 2.5 3 1 1 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR28139.1 - 0.36 10.9 2.1 8.3 6.6 0.1 3.1 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Ras PF00071.22 CAR28140.1 - 8.6e-51 171.8 0.0 1e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR28140.1 - 8.4e-31 106.7 0.1 2.2e-30 105.3 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR28140.1 - 1.7e-11 43.9 0.0 2.4e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR28140.1 - 0.00074 19.6 0.0 0.0015 18.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CAR28140.1 - 0.00074 19.9 0.2 0.0065 16.8 0.2 2.2 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 CAR28140.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR28140.1 - 0.012 15.1 0.4 0.057 12.9 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CAR28140.1 - 0.017 14.6 0.0 0.028 13.8 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Pox_A32 PF04665.12 CAR28140.1 - 0.018 14.5 0.1 0.033 13.7 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 CAR28140.1 - 0.018 14.2 2.5 2 7.5 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 CAR28140.1 - 0.025 14.5 0.1 8.1 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ATPase PF06745.13 CAR28140.1 - 0.025 13.9 0.2 0.039 13.3 0.2 1.2 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 CAR28140.1 - 0.029 13.9 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CAR28140.1 - 0.056 13.2 0.1 0.096 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAR28140.1 - 0.098 12.8 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CAR28140.1 - 0.098 12.7 0.1 0.23 11.4 0.1 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 CAR28140.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 CAR28140.1 - 0.15 11.3 0.3 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Septin ADIP PF11559.8 CAR28141.1 - 5.9e-06 26.4 2.1 5.9e-06 26.4 2.1 2.9 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding FliS PF02561.14 CAR28141.1 - 0.0028 17.9 1.8 0.048 13.9 0.1 2.8 2 1 1 3 3 3 1 Flagellar protein FliS Lipoprotein_6 PF01441.19 CAR28141.1 - 0.084 12.9 1.3 0.15 12.1 0.1 2.0 2 1 0 2 2 2 0 Lipoprotein Pox_A_type_inc PF04508.12 CAR28141.1 - 0.092 12.6 0.6 26 4.9 0.1 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat G-gamma PF00631.22 CAR28141.1 - 0.14 12.2 1.0 6.8 6.8 0.1 2.6 2 0 0 2 2 2 0 GGL domain Cep57_MT_bd PF06657.13 CAR28141.1 - 0.14 12.6 5.8 1.9 9.0 0.1 3.6 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 PKcGMP_CC PF16808.5 CAR28141.1 - 0.35 10.7 4.8 5.4 7.0 0.1 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BST2 PF16716.5 CAR28141.1 - 6.2 7.5 14.3 2.4 8.8 1.8 3.2 3 1 0 4 4 4 0 Bone marrow stromal antigen 2 ATP_sub_h PF10775.9 CAR28142.1 - 1.2e-24 86.0 0.5 1.9e-24 85.4 0.5 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h FAM176 PF14851.6 CAR28143.1 - 0.0057 16.3 0.1 0.0071 16.0 0.1 1.1 1 0 0 1 1 1 1 FAM176 family TRP PF06011.12 CAR28143.1 - 0.072 11.8 0.1 0.088 11.5 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF5305 PF17231.2 CAR28143.1 - 0.073 12.5 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) zf-U1 PF06220.12 CAR28144.1 - 2.5e-18 65.6 5.2 5.3e-18 64.5 5.2 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-Dof PF02701.15 CAR28144.1 - 0.43 10.7 8.3 1.8 8.8 2.3 2.4 1 1 1 2 2 2 0 Dof domain, zinc finger GTP_EFTU PF00009.27 CAR28145.1 - 1.3e-59 201.0 0.2 1.7e-59 200.6 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CAR28145.1 - 6.3e-27 94.1 0.0 1.3e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CAR28145.1 - 1.6e-20 73.2 1.4 4e-20 72.0 1.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAR28145.1 - 1.3e-05 25.2 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CAR28145.1 - 0.0064 16.3 0.3 3.3 7.4 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 CAR28145.1 - 0.0091 15.9 0.2 0.036 14.0 0.0 1.8 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 CAR28145.1 - 0.091 12.3 1.4 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G_glu_transpept PF01019.21 CAR28146.1 - 1.5e-143 479.2 0.0 1.8e-143 479.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1708 PF08101.11 CAR28147.1 - 2.9e-142 474.8 12.1 2.9e-142 474.8 12.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 CAR28147.1 - 0.058 13.2 0.4 0.27 11.1 0.0 2.3 3 0 0 3 3 3 0 RhoGAP domain Nop14 PF04147.12 CAR28148.1 - 0.1 10.8 32.5 0.1 10.8 32.5 1.1 1 0 0 1 1 1 0 Nop14-like family CNDH2_C PF16858.5 CAR28148.1 - 0.21 11.4 24.3 0.24 11.2 24.3 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SDA1 PF05285.12 CAR28148.1 - 0.29 10.5 35.9 0.3 10.5 35.9 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CAR28148.1 - 0.48 8.7 29.8 0.53 8.5 29.8 1.2 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 CAR28148.1 - 1.9 7.4 20.6 2.5 7.0 20.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 CAR28148.1 - 2.9 6.6 16.4 3.8 6.1 16.4 1.2 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.13 CAR28148.1 - 7.8 5.2 29.3 12 4.6 29.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cellulase PF00150.18 CAR28149.1 - 1.7e-13 50.7 1.9 3.8e-13 49.5 1.5 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Importin_rep PF18773.1 CAR28149.1 - 0.092 12.5 0.9 0.22 11.3 0.9 1.6 1 0 0 1 1 1 0 Importin 13 repeat SNF2_N PF00176.23 CAR28150.1 - 2.6e-59 200.7 0.4 5.5e-59 199.7 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR28150.1 - 3e-17 63.0 0.5 2.6e-16 59.9 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 CAR28150.1 - 2.2e-05 24.3 5.8 8.7e-05 22.4 6.0 2.0 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CAR28150.1 - 0.0011 18.7 3.2 0.0027 17.5 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR28150.1 - 0.0013 19.0 4.0 0.0032 17.8 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.15 CAR28150.1 - 0.0015 18.5 0.0 0.0062 16.6 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 CAR28150.1 - 0.0036 17.3 3.7 0.0086 16.1 3.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAR28150.1 - 0.036 13.9 6.4 0.087 12.7 6.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR28150.1 - 0.055 13.3 4.8 0.13 12.2 4.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4172 PF13776.6 CAR28150.1 - 0.078 13.3 0.0 0.43 10.9 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) zf-C3HC4_2 PF13923.6 CAR28150.1 - 0.18 11.7 3.2 0.41 10.5 3.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HRI1 PF16815.5 CAR28151.1 - 7.2e-36 124.0 0.0 8.1e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 Cellulase PF00150.18 CAR28152.1 - 9e-12 45.0 0.0 2.9e-07 30.2 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 CAR28152.1 - 2.3e-09 37.6 0.0 4.9e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain DNA_primase_S PF01896.19 CAR28153.1 - 4.3e-65 219.1 0.4 6.4e-65 218.5 0.2 1.4 2 0 0 2 2 2 1 DNA primase small subunit Scramblase PF03803.15 CAR28153.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Scramblase HSP20 PF00011.21 CAR28154.1 - 6e-23 80.9 2.5 9.4e-23 80.3 2.5 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CAR28154.1 - 1.7e-07 30.6 0.1 3.3e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA SNAD3 PF18749.1 CAR28154.1 - 0.06 12.5 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 Proteasome PF00227.26 CAR28155.1 - 7.2e-41 139.8 0.0 8.2e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Uteroglobin PF01099.17 CAR28155.1 - 0.051 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Uteroglobin family HA2 PF04408.23 CAR28156.1 - 1.4e-20 73.6 0.6 4.8e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CAR28156.1 - 2.3e-16 59.9 0.0 5.5e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CAR28156.1 - 3.1e-14 53.3 0.0 1.2e-13 51.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CAR28156.1 - 4.2e-11 43.0 0.1 1.3e-10 41.5 0.1 1.9 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 CAR28156.1 - 2e-06 27.7 0.3 7.4e-06 25.8 0.3 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR28156.1 - 1.7e-05 25.1 0.0 4.3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CAR28156.1 - 0.00029 20.0 0.1 0.0016 17.6 0.4 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 CAR28156.1 - 0.00033 20.4 0.0 0.00062 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR28156.1 - 0.0058 17.0 0.1 0.012 15.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CAR28156.1 - 0.012 15.2 0.2 0.037 13.6 0.2 1.8 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 CAR28156.1 - 0.023 14.7 0.5 0.31 11.1 0.2 2.7 2 1 0 2 2 1 0 AAA domain AAA PF00004.29 CAR28156.1 - 0.063 13.7 0.0 0.35 11.3 0.0 2.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CAR28156.1 - 0.066 12.7 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 CAR28156.1 - 0.23 12.0 0.1 0.23 12.0 0.1 3.5 2 2 1 3 3 2 0 ABC transporter AAA_23 PF13476.6 CAR28156.1 - 0.49 10.9 0.0 0.49 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 CAR28156.1 - 0.65 10.4 0.0 0.65 10.4 0.0 2.1 3 0 0 3 3 3 0 AAA ATPase domain Amino_oxidase PF01593.24 CAR28157.1 - 2.8e-17 63.2 0.0 3.3e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CAR28157.1 - 5.6e-13 48.9 0.0 1.2e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CAR28157.1 - 0.00015 22.3 0.0 0.0014 19.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CAR28157.1 - 0.00017 20.9 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CAR28157.1 - 0.00037 20.2 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 CAR28157.1 - 0.0045 15.6 0.0 0.09 11.3 0.0 2.2 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 CAR28157.1 - 0.016 14.5 0.0 0.036 13.3 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAR28157.1 - 0.017 15.1 0.0 0.083 12.9 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding RRM_1 PF00076.22 CAR28158.1 - 2.3e-11 43.4 0.0 4.5e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR28158.1 - 1.9e-06 27.5 0.1 1.9e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR28158.1 - 0.0014 18.4 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Occluded RNA-recognition motif AMP-binding PF00501.28 CAR28159.1 - 3.7e-70 236.6 0.0 4.8e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EB1 PF03271.17 CAR28160.1 - 4.4e-17 62.0 0.3 8.9e-17 61.1 0.3 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CAR28160.1 - 9.1e-06 25.8 0.4 3.6e-05 23.9 0.4 1.9 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 CAR28160.1 - 0.00078 19.5 0.3 0.0017 18.4 0.3 1.6 1 0 0 1 1 1 1 CH-like domain in sperm protein zf-C4H2 PF10146.9 CAR28160.1 - 0.0071 16.7 0.6 0.015 15.6 0.2 1.6 1 1 0 1 1 1 1 Zinc finger-containing protein MPS2 PF17060.5 CAR28160.1 - 0.072 12.3 0.5 1.7 7.9 0.2 2.0 2 0 0 2 2 2 0 Monopolar spindle protein 2 HrpB7 PF09486.10 CAR28160.1 - 0.096 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Peptidase_M41 PF01434.18 CAR28161.1 - 1.2e-67 227.5 0.0 2e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CAR28161.1 - 1e-42 145.7 0.0 2.4e-42 144.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR28161.1 - 5.2e-12 45.4 0.3 1.9e-11 43.6 0.3 2.0 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CAR28161.1 - 0.002 18.5 0.1 0.0057 17.0 0.1 1.8 1 0 0 1 1 1 1 FtsH Extracellular TIP49 PF06068.13 CAR28161.1 - 0.0027 17.0 0.0 0.0087 15.3 0.0 1.9 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CAR28161.1 - 0.0069 16.7 2.4 0.63 10.3 0.1 3.2 4 0 0 4 4 3 1 AAA domain RuvB_N PF05496.12 CAR28161.1 - 0.0095 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CAR28161.1 - 0.011 15.8 0.7 0.073 13.1 0.1 2.8 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAR28161.1 - 0.013 15.6 0.1 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 CAR28161.1 - 0.013 15.9 0.4 0.035 14.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CAR28161.1 - 0.017 14.9 0.0 0.044 13.5 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 CAR28161.1 - 0.097 13.0 0.2 0.097 13.0 0.2 2.8 3 1 0 3 3 2 0 AAA ATPase domain AAA_18 PF13238.6 CAR28161.1 - 0.14 12.7 0.2 2.6 8.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain V-ATPase_G_2 PF16999.5 CAR28161.1 - 3.1 8.3 6.7 6.8 7.2 0.3 2.4 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit HMG_box PF00505.19 CAR28162.1 - 1e-14 54.6 7.0 4.1e-14 52.7 7.0 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CAR28162.1 - 5e-06 27.0 1.8 1.5e-05 25.5 1.8 1.8 1 1 0 1 1 1 1 HMG-box domain Ribosomal_S5 PF00333.20 CAR28163.1 - 6.9e-25 86.8 0.0 1.2e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CAR28163.1 - 1.6e-21 75.6 0.0 3.1e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain dUTPase PF00692.19 CAR28164.1 - 4.5e-46 155.7 0.1 5e-46 155.6 0.1 1.0 1 0 0 1 1 1 1 dUTPase Med22 PF06179.12 CAR28165.1 - 3.5e-23 81.8 0.4 4.1e-23 81.6 0.4 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex MIS13 PF08202.11 CAR28166.1 - 4.6e-54 183.8 14.0 6.2e-54 183.3 14.0 1.2 1 0 0 1 1 1 1 Mis12-Mtw1 protein family HalX PF08663.10 CAR28166.1 - 0.13 12.6 3.0 4.8 7.6 0.1 2.6 2 0 0 2 2 2 0 HalX domain Sedlin_N PF04628.13 CAR28167.1 - 1e-52 177.7 0.0 1.5e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CAR28167.1 - 2.1e-06 27.7 0.0 4.4e-06 26.7 0.0 1.6 1 1 0 1 1 1 1 Sybindin-like family Cut8 PF08559.10 CAR28170.1 - 2.2e-68 230.5 6.8 2.9e-68 230.1 6.8 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein ANAPC4_WD40 PF12894.7 CAR28171.1 - 6.1e-07 29.7 2.4 0.007 16.6 0.3 4.8 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CAR28171.1 - 2e-06 27.5 1.2 4.8e-05 23.1 1.2 2.4 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 CAR28171.1 - 0.00018 21.3 0.0 0.44 10.6 0.1 3.6 3 0 0 3 3 3 2 PQQ enzyme repeat WD40 PF00400.32 CAR28171.1 - 0.0064 17.3 3.4 24 6.0 0.2 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF4479 PF14794.6 CAR28171.1 - 0.011 15.6 0.1 0.031 14.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) WD40_like PF17005.5 CAR28171.1 - 0.013 14.8 0.0 6 6.1 0.3 2.5 2 1 0 2 2 2 0 WD40-like domain RAB3GAP2_N PF14655.6 CAR28171.1 - 0.11 11.7 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Lum_binding PF00677.17 CAR28172.1 - 5e-45 151.4 1.2 1.6e-21 76.1 0.0 2.3 2 0 0 2 2 2 2 Lumazine binding domain Asp PF00026.23 CAR28173.1 - 1.3e-70 238.4 0.2 1.3e-70 238.4 0.2 1.4 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR28173.1 - 2.4e-12 47.4 0.1 2.4e-12 47.4 0.1 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal WVELL PF14043.6 CAR28173.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 WVELL protein BAG PF02179.16 CAR28174.1 - 5.5e-16 58.8 0.8 1.1e-15 57.8 0.8 1.5 1 0 0 1 1 1 1 BAG domain PAF-AH_p_II PF03403.13 CAR28174.1 - 0.1 11.1 0.3 0.17 10.4 0.3 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II HEAT PF02985.22 CAR28175.1 - 0.016 15.4 0.0 0.58 10.6 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat Astro_capsid_p PF12226.8 CAR28175.1 - 3.2 6.8 7.8 5.1 6.2 7.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAD_binding_1 PF00667.20 CAR28176.1 - 3.7e-70 235.9 0.0 5.9e-70 235.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CAR28176.1 - 7.7e-08 33.0 0.0 2.9e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 CAR28176.1 - 0.00087 19.6 0.0 0.0023 18.2 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II FAD_binding_6 PF00970.24 CAR28176.1 - 0.17 12.2 0.0 0.48 10.8 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain SMC_N PF02463.19 CAR28177.1 - 4.1e-72 242.2 0.0 6.1e-71 238.4 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CAR28177.1 - 7.8e-21 74.6 0.2 2.3e-20 73.0 0.2 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CAR28177.1 - 4.2e-15 56.8 2.5 4.2e-15 56.8 2.5 6.8 3 2 0 3 3 1 1 AAA domain AAA_21 PF13304.6 CAR28177.1 - 5.8e-11 42.8 2.6 6.9e-05 22.8 0.2 3.1 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CAR28177.1 - 5.3e-05 22.9 0.1 0.00041 20.0 0.0 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_13 PF13166.6 CAR28177.1 - 8.4e-05 21.4 23.3 8.4e-05 21.4 23.3 5.0 3 2 3 6 6 6 3 AAA domain AAA_15 PF13175.6 CAR28177.1 - 0.00091 19.0 18.7 0.00091 19.0 18.7 4.9 2 2 0 3 3 2 1 AAA ATPase domain Spc7 PF08317.11 CAR28177.1 - 0.0021 17.0 12.7 0.0021 17.0 12.7 6.3 3 2 3 6 6 6 3 Spc7 kinetochore protein EzrA PF06160.12 CAR28177.1 - 0.0028 15.9 8.1 0.0028 15.9 8.1 7.0 3 2 4 7 7 7 3 Septation ring formation regulator, EzrA Pox_A21 PF05323.12 CAR28177.1 - 0.012 16.1 1.9 5.4 7.6 0.6 3.1 2 0 0 2 2 2 0 Poxvirus A21 Protein Baculo_PEP_C PF04513.12 CAR28177.1 - 0.016 15.2 36.8 0.059 13.4 4.8 6.3 3 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CAR28177.1 - 0.032 14.3 62.5 0.91 9.6 8.4 8.9 3 2 5 9 9 9 0 Protein of unknown function (DUF1664) DUF3866 PF12982.7 CAR28177.1 - 0.055 12.6 0.9 5.6 6.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3866) DUF4226 PF10774.9 CAR28177.1 - 0.61 10.4 3.4 3.9 7.8 0.2 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) DUF3584 PF12128.8 CAR28177.1 - 4.4 4.7 75.2 0.13 9.8 15.8 4.5 2 2 2 4 4 4 0 Protein of unknown function (DUF3584) HrpB7 PF09486.10 CAR28177.1 - 5 7.5 26.0 9.7 6.6 1.9 5.6 2 2 1 5 5 5 0 Bacterial type III secretion protein (HrpB7) Ribosomal_L2_C PF03947.18 CAR28178.1 - 1.4e-43 148.1 4.5 2.2e-43 147.4 4.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CAR28178.1 - 2e-13 50.1 0.2 6.1e-13 48.5 0.2 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain RRM_1 PF00076.22 CAR28179.1 - 5.9e-20 70.9 0.7 1.2e-13 50.7 0.1 3.1 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR28179.1 - 0.015 15.4 0.0 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif DbpA PF03880.15 CAR28179.1 - 0.019 14.9 1.7 0.5 10.4 0.2 2.8 3 0 0 3 3 3 0 DbpA RNA binding domain RRM_occluded PF16842.5 CAR28179.1 - 0.12 12.2 0.1 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Occluded RNA-recognition motif UCR_hinge PF02320.16 CAR28180.1 - 3.3e-27 94.5 3.4 3.3e-27 94.5 3.4 1.7 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein DNA_pol_phi PF04931.13 CAR28180.1 - 0.13 10.3 23.3 0.14 10.3 23.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 CAR28180.1 - 0.13 10.4 17.0 0.14 10.3 17.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1115 PF06544.12 CAR28180.1 - 0.2 11.8 2.9 0.24 11.5 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) DUF913 PF06025.12 CAR28180.1 - 0.22 10.5 1.0 0.23 10.4 1.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Mpp10 PF04006.12 CAR28180.1 - 0.25 9.8 14.6 0.27 9.6 14.6 1.0 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 CAR28180.1 - 0.25 9.6 9.4 0.23 9.7 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein PDDEXK_6 PF04720.12 CAR28180.1 - 0.32 10.9 2.6 0.36 10.8 2.6 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function RPN2_C PF18004.1 CAR28180.1 - 0.52 10.2 3.1 0.62 10.0 3.1 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain BUD22 PF09073.10 CAR28180.1 - 0.74 9.1 13.7 0.84 8.9 13.7 1.1 1 0 0 1 1 1 0 BUD22 GCIP PF13324.6 CAR28180.1 - 1 8.9 6.4 1.2 8.7 6.4 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting RRN3 PF05327.11 CAR28180.1 - 1.5 7.2 7.8 1.5 7.3 7.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop53 PF07767.11 CAR28180.1 - 3.4 7.0 12.4 3.6 6.9 12.4 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2457 PF10446.9 CAR28180.1 - 5.3 6.1 21.7 5.5 6.0 21.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.16 CAR28180.1 - 5.6 6.1 8.3 5.8 6.0 8.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GEN1_C PF18380.1 CAR28180.1 - 7.4 7.5 11.6 6.4 7.7 10.6 1.4 1 1 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Cwf_Cwc_15 PF04889.12 CAR28180.1 - 8.7 6.0 15.5 9.8 5.8 15.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HLH PF00010.26 CAR28181.1 - 1.1e-10 41.3 0.1 2.3e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ARGLU PF15346.6 CAR28181.1 - 0.074 12.9 0.3 0.074 12.9 0.3 1.6 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DUF4602 PF15375.6 CAR28182.1 - 1.8e-06 28.3 5.6 1.8e-06 28.3 5.6 3.4 2 1 1 3 3 3 1 Domain of unknown function (DUF4602) SIP1 PF04938.12 CAR28182.1 - 0.14 11.8 1.9 0.34 10.6 1.7 1.7 1 1 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DNA_pol_phi PF04931.13 CAR28182.1 - 3.9 5.5 16.7 5.3 5.0 16.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi His_biosynth PF00977.21 CAR28183.1 - 2.1e-26 92.8 0.0 2.5e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein RNA_pol_A_bac PF01000.26 CAR28184.1 - 3.3e-32 111.2 0.1 6.9e-32 110.1 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CAR28184.1 - 4.5e-16 58.0 0.0 6.1e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Tim44 PF04280.15 CAR28186.1 - 5.8e-36 123.8 0.1 1.9e-35 122.1 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain Peptidase_C48 PF02902.19 CAR28187.1 - 4.5e-41 141.1 3.4 4.5e-41 141.1 3.4 2.0 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain GHD PF17834.1 CAR28187.1 - 0.00025 21.0 0.3 0.0015 18.6 0.1 2.3 2 0 0 2 2 2 1 Beta-sandwich domain in beta galactosidase RINGv PF12906.7 CAR28188.1 - 4.4e-14 52.3 6.2 8e-14 51.5 6.2 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CAR28188.1 - 0.33 11.3 6.2 0.86 10.0 6.3 1.7 1 1 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 CAR28188.1 - 0.5 10.6 4.2 1 9.6 4.2 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain LAP1C PF05609.12 CAR28188.1 - 1 8.3 7.4 1.6 7.7 7.4 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Pex14_N PF04695.13 CAR28188.1 - 5.4 7.7 14.0 0.095 13.4 2.8 2.4 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DivIC PF04977.15 CAR28189.1 - 0.14 11.9 0.2 0.14 11.9 0.2 3.6 4 1 1 5 5 5 0 Septum formation initiator DUF5082 PF16888.5 CAR28189.1 - 0.58 10.4 14.7 0.057 13.7 5.8 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF5082) FapA PF03961.13 CAR28189.1 - 5.5 5.5 11.4 7.3 5.1 10.7 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A ANAPC_CDC26 PF10471.9 CAR28190.1 - 1.1e-14 54.9 0.8 1.1e-14 54.9 0.8 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 Babuvirus_MP PF07234.11 CAR28190.1 - 0.2 11.8 0.0 0.28 11.4 0.0 1.1 1 0 0 1 1 1 0 Movement and RNA silencing protein MMgT PF10270.9 CAR28191.1 - 1.1e-25 89.9 0.3 1.6e-25 89.3 0.3 1.3 1 1 0 1 1 1 1 Membrane magnesium transporter MKT1_N PF12247.8 CAR28191.1 - 0.012 15.9 0.1 0.021 15.1 0.1 1.6 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication STAG PF08514.11 CAR28192.1 - 6.1e-25 87.3 0.0 2.2e-24 85.5 0.0 2.0 1 0 0 1 1 1 1 STAG domain HEAT PF02985.22 CAR28192.1 - 0.00053 20.0 0.1 0.52 10.7 0.1 3.2 2 0 0 2 2 2 1 HEAT repeat Erf4 PF10256.9 CAR28192.1 - 0.002 18.2 1.7 0.034 14.2 0.0 3.2 3 1 0 3 3 3 1 Golgin subfamily A member 7/ERF4 family HEAT_2 PF13646.6 CAR28192.1 - 0.1 13.0 0.0 0.36 11.3 0.0 1.9 1 0 0 1 1 1 0 HEAT repeats DUF4042 PF13251.6 CAR28192.1 - 0.18 11.5 0.9 5.8 6.6 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4042) Cnd1 PF12717.7 CAR28192.1 - 0.27 11.3 1.7 1.4 9.0 0.2 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Condensin2nSMC PF12422.8 CAR28192.1 - 0.48 10.6 2.3 0.89 9.7 0.2 2.5 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit RasGEF_N PF00618.20 CAR28192.1 - 0.49 10.7 5.7 2.8 8.2 0.3 4.3 3 1 0 3 3 3 0 RasGEF N-terminal motif AMPK1_CBM PF16561.5 CAR28193.1 - 3.7e-05 23.8 0.3 7.3e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Zip PF02535.22 CAR28194.1 - 8.6e-55 186.3 15.3 1.4e-39 136.3 3.9 2.3 2 1 1 3 3 3 2 ZIP Zinc transporter Bap31 PF05529.12 CAR28194.1 - 0.01 15.7 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region DUF347 PF03988.12 CAR28194.1 - 0.15 12.3 5.7 0.11 12.7 2.1 2.6 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) FtsX PF02687.21 CAR28194.1 - 1.3 9.6 11.2 0.36 11.3 1.7 3.5 3 1 0 3 3 3 0 FtsX-like permease family SWIRM PF04433.17 CAR28195.1 - 1.6e-28 98.8 0.9 3.8e-28 97.6 0.2 2.1 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.17 CAR28195.1 - 3.9e-14 52.2 2.8 5.9e-14 51.6 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CAR28195.1 - 1.3e-08 34.9 0.1 2.8e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 CAR28195.1 - 2.6e-07 30.5 7.3 2.6e-07 30.5 7.3 2.3 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 CAR28195.1 - 1e-06 28.9 0.1 7.5e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-UBR PF02207.20 CAR28195.1 - 0.0064 16.6 0.9 0.012 15.7 0.9 1.4 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-CCHC_2 PF13696.6 CAR28195.1 - 0.011 15.6 5.2 0.67 9.8 0.2 2.3 2 0 0 2 2 2 0 Zinc knuckle SNF2_N PF00176.23 CAR28196.1 - 8.1e-67 225.4 0.3 1.3e-66 224.8 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR28196.1 - 4.8e-22 78.4 0.0 2.8e-20 72.7 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR28196.1 - 2.2e-08 34.3 0.0 5.4e-07 29.8 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CAR28196.1 - 4.5e-08 32.6 0.1 1.2e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CAR28196.1 - 0.00015 21.6 0.0 0.00061 19.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CAR28196.1 - 0.00041 19.6 0.0 0.0015 17.8 0.0 2.0 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase cNMP_binding PF00027.29 CAR28197.1 - 2e-39 133.5 0.1 4.1e-19 68.4 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CAR28197.1 - 3.2e-12 45.9 2.8 1.3e-11 44.0 2.8 2.0 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Erg28 PF03694.13 CAR28198.1 - 4.5e-45 152.5 1.3 6.1e-45 152.1 1.3 1.2 1 0 0 1 1 1 1 Erg28 like protein F_actin_cap_B PF01115.17 CAR28199.1 - 5.7e-91 304.4 0.2 6.6e-91 304.2 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Pkinase PF00069.25 CAR28200.1 - 1.2e-57 195.3 4.4 3.8e-50 170.7 0.3 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28200.1 - 4.4e-18 65.5 0.7 1e-13 51.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CAR28200.1 - 8.1e-06 25.9 0.1 3.5e-05 23.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CAR28200.1 - 0.0037 16.9 0.2 0.0093 15.6 0.1 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CAR28200.1 - 0.014 14.2 0.3 0.028 13.2 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase DUF496 PF04363.12 CAR28200.1 - 0.016 15.2 3.8 0.17 11.9 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF496) Kdo PF06293.14 CAR28200.1 - 0.055 12.8 1.0 0.13 11.6 1.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PC_rep PF01851.22 CAR28200.1 - 0.2 12.2 2.1 15 6.2 0.2 3.0 2 0 0 2 2 2 0 Proteasome/cyclosome repeat UPF0565 PF10561.9 CAR28201.1 - 0.038 13.2 3.7 2.9 7.0 0.2 2.3 1 1 0 2 2 2 0 Uncharacterised protein family UPF0565 bZIP_1 PF00170.21 CAR28202.1 - 3e-15 56.1 1.8 6.5e-15 55.0 1.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CAR28202.1 - 0.00021 21.3 7.5 0.00056 19.9 7.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CAR28202.1 - 0.004 17.6 0.3 0.0083 16.6 0.3 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Totivirus_coat PF05518.11 CAR28202.1 - 0.048 11.7 3.2 0.065 11.3 3.2 1.1 1 0 0 1 1 1 0 Totivirus coat protein Secretin_N_2 PF07655.13 CAR28202.1 - 1.5 9.4 11.6 1.5 9.4 9.2 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Bac_rhodopsin PF01036.18 CAR28203.1 - 5.9e-06 26.0 0.3 6.9e-06 25.8 0.3 1.2 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4476 PF14771.6 CAR28204.1 - 0.045 14.1 0.2 0.13 12.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) Pex24p PF06398.11 CAR28204.1 - 1.4 7.8 5.5 2.3 7.1 5.5 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Not3 PF04065.15 CAR28206.1 - 3.1e-81 272.2 28.0 3.1e-81 272.2 28.0 2.0 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CAR28206.1 - 1.3e-21 77.0 0.5 4.9e-21 75.2 0.5 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 CAR28206.1 - 0.0046 17.3 2.6 0.0046 17.3 2.6 4.1 4 0 0 4 4 4 1 Syntaxin-like protein TauD PF02668.16 CAR28207.1 - 1.2e-38 133.5 0.1 1.5e-38 133.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA PF00004.29 CAR28208.1 - 3.7e-39 134.2 0.0 6.5e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CAR28208.1 - 3.8e-09 36.4 0.0 2.7e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 CAR28208.1 - 1.6e-08 34.2 0.0 3.2e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CAR28208.1 - 4.6e-05 23.7 0.1 0.0021 18.3 0.1 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CAR28208.1 - 8.2e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CAR28208.1 - 9.6e-05 22.6 0.1 0.00024 21.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CAR28208.1 - 0.00074 19.5 0.0 0.0036 17.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAR28208.1 - 0.0017 18.8 0.9 0.011 16.1 0.1 2.4 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 CAR28208.1 - 0.0049 16.9 0.0 0.048 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR28208.1 - 0.0066 16.6 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CAR28208.1 - 0.0068 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CAR28208.1 - 0.0082 15.5 1.1 0.014 14.8 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CAR28208.1 - 0.012 15.1 0.1 0.23 11.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CAR28208.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 CAR28208.1 - 0.026 13.7 0.0 0.06 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Chromo PF00385.24 CAR28208.1 - 0.027 14.4 1.7 0.068 13.1 0.0 2.5 3 0 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain AAA_24 PF13479.6 CAR28208.1 - 0.057 13.1 0.2 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CAR28208.1 - 0.086 12.2 0.0 3.1 7.2 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 CAR28208.1 - 0.086 12.8 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CAR28208.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 CAR28208.1 - 0.53 10.8 0.0 0.53 10.8 0.0 2.9 3 2 1 4 4 2 0 AAA domain Imm31 PF15591.6 CAR28209.1 - 0.082 12.8 0.1 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 31 DnaJ-X PF14308.6 CAR28210.1 - 2.8e-59 200.1 7.2 2.8e-59 200.1 7.2 2.3 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 CAR28210.1 - 5.1e-26 90.6 0.8 4.9e-25 87.4 0.7 2.8 2 0 0 2 2 2 1 DnaJ domain PEPCK_N PF17297.2 CAR28210.1 - 0.049 13.2 0.9 0.34 10.5 0.2 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase N-terminal domain Apq12 PF12716.7 CAR28211.1 - 0.00027 20.8 13.7 0.00061 19.7 13.7 1.6 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Peptidase_M50B PF13398.6 CAR28211.1 - 0.088 12.4 5.4 0.12 12.0 5.4 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Pex24p PF06398.11 CAR28211.1 - 0.28 10.1 6.5 0.29 10.1 6.5 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Complex1_LYR PF05347.15 CAR28212.1 - 4.9e-18 64.9 1.2 6e-18 64.6 1.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CAR28212.1 - 0.00072 20.3 0.6 0.00083 20.1 0.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Ofd1_CTDD PF10637.9 CAR28213.1 - 6.6e-91 304.2 2.6 8.8e-90 300.5 2.1 2.2 2 0 0 2 2 2 1 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CAR28213.1 - 2.5e-26 92.1 0.0 6.9e-26 90.7 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CAR28213.1 - 5.8e-14 52.8 0.0 1.3e-13 51.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CAR28213.1 - 0.0094 16.4 0.1 0.03 14.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily BAR_2 PF10455.9 CAR28214.1 - 1.1e-77 261.0 9.8 1.5e-77 260.6 8.1 1.9 1 1 1 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CAR28214.1 - 5.8e-17 62.1 8.8 1.8e-16 60.5 8.8 1.8 1 1 0 1 1 1 1 BAR domain BCDHK_Adom3 PF10436.9 CAR28215.1 - 1.7e-26 93.0 1.5 3.1e-26 92.2 1.5 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CAR28215.1 - 7.5e-14 52.2 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CAR28215.1 - 2.5e-05 24.1 0.0 4.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 CAR28215.1 - 0.0037 17.2 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain Ribosomal_S18 PF01084.20 CAR28216.1 - 5.6e-20 71.3 0.0 1.5e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 Cupin_8 PF13621.6 CAR28217.1 - 4.1e-09 36.5 1.8 9.1e-08 32.1 1.4 2.6 1 1 0 1 1 1 1 Cupin-like domain PHD PF00628.29 CAR28217.1 - 9.4e-06 25.4 5.9 1.9e-05 24.5 5.9 1.5 1 0 0 1 1 1 1 PHD-finger JmjC PF02373.22 CAR28217.1 - 0.00044 20.7 0.0 0.016 15.6 0.0 3.1 2 1 0 2 2 2 1 JmjC domain, hydroxylase JHD PF17811.1 CAR28217.1 - 0.0009 19.8 0.1 0.0036 17.8 0.0 2.1 2 0 0 2 2 2 1 Jumonji helical domain Cupin_4 PF08007.12 CAR28217.1 - 0.015 14.8 0.5 0.023 14.2 0.0 1.6 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_1 PF00190.22 CAR28217.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Cupin zf-HC5HC2H PF13771.6 CAR28217.1 - 0.11 12.7 2.9 0.26 11.6 2.9 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 CAR28217.1 - 0.19 11.6 4.1 0.48 10.4 4.1 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 CAR28217.1 - 0.21 11.7 4.2 0.75 9.9 4.2 1.9 1 1 0 1 1 1 0 PHD-finger NAD_binding_1 PF00175.21 CAR28218.1 - 6.5e-32 110.4 0.0 1.1e-31 109.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CAR28218.1 - 1.9e-30 105.1 0.0 3.1e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CAR28218.1 - 6.8e-06 26.3 0.0 0.003 17.7 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain AA_kinase PF00696.28 CAR28219.1 - 5.2e-40 137.5 0.0 9.8e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 CAR28219.1 - 7.8e-11 41.6 0.1 3.7e-05 23.4 0.2 2.9 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 CAR28219.1 - 1.5e-06 27.9 2.2 0.00023 20.9 0.9 2.4 2 0 0 2 2 2 2 ACT domain Cyt-b5 PF00173.28 CAR28220.1 - 1.6e-17 63.4 0.1 7.6e-17 61.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF3377 PF11857.8 CAR28220.1 - 0.0055 16.6 0.9 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3377) ArfGap PF01412.18 CAR28221.1 - 2.4e-37 127.6 0.2 5.5e-37 126.4 0.2 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF515 PF04415.12 CAR28221.1 - 3.7 5.8 8.2 6 5.1 8.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Mito_carr PF00153.27 CAR28222.1 - 1.3e-47 159.7 2.5 3.8e-16 58.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CBM_21 PF03370.13 CAR28223.1 - 1.4e-27 96.1 0.1 2.1e-27 95.5 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CAR28223.1 - 1.6e-12 47.8 0.2 2.7e-12 47.1 0.2 1.3 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) WD40 PF00400.32 CAR28224.1 - 3e-36 122.8 23.5 1.4e-06 28.9 0.7 7.7 7 1 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 CAR28224.1 - 2.8e-12 46.3 1.5 6.3e-12 45.2 1.5 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 CAR28224.1 - 3.1e-11 42.6 9.4 0.05 12.2 0.1 6.0 2 2 2 6 6 6 4 Nucleoporin Nup120/160 F-box PF00646.33 CAR28224.1 - 6.5e-10 38.6 0.8 1.5e-09 37.5 0.8 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 CAR28224.1 - 1.1e-06 28.8 2.0 0.57 10.5 0.0 5.3 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAR28224.1 - 0.00039 19.8 0.1 2 7.7 0.0 3.3 2 1 1 3 3 3 2 WD40-like domain PRANC PF09372.10 CAR28224.1 - 0.098 13.0 0.2 0.35 11.2 0.2 1.8 1 1 0 1 1 1 0 PRANC domain HisG PF01634.18 CAR28225.1 - 1.7e-51 174.3 0.1 2.3e-51 173.9 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 CAR28225.1 - 8.4e-28 96.3 0.0 1.5e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain EXS PF03124.14 CAR28226.1 - 9.4e-86 288.1 23.8 1.4e-85 287.6 23.8 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CAR28226.1 - 5.8e-32 112.1 16.7 1.4e-16 61.5 11.3 3.3 1 1 1 2 2 2 2 SPX domain EMC3_TMCO1 PF01956.16 CAR28226.1 - 0.0091 15.7 0.4 0.0091 15.7 0.4 2.7 2 1 1 3 3 3 1 Integral membrane protein EMC3/TMCO1-like PhoLip_ATPase_C PF16212.5 CAR28227.1 - 1.3e-49 169.3 11.3 1.3e-49 169.3 11.3 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CAR28227.1 - 7.2e-19 67.3 2.1 1.4e-18 66.3 2.1 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CAR28227.1 - 4.3e-12 45.9 0.0 1.3e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CAR28227.1 - 4.7e-12 45.8 0.0 5e-11 42.5 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CAR28227.1 - 1.1e-11 45.5 0.5 3.2e-06 27.6 0.4 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CAR28227.1 - 0.0084 15.9 0.3 0.032 14.0 0.0 2.0 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Steroid_dh PF02544.16 CAR28228.1 - 3.1e-07 30.5 1.2 3.1e-07 30.5 1.2 2.1 1 1 2 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase Transp_cyt_pur PF02133.15 CAR28229.1 - 8.6e-87 291.7 30.7 1e-86 291.5 30.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ribosomal_L34e PF01199.18 CAR28230.1 - 3.4e-41 139.4 5.3 3.4e-41 139.4 5.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e ATG27 PF09451.10 CAR28232.1 - 7.8e-51 173.4 0.1 9.3e-51 173.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 HTH_36 PF13730.6 CAR28232.1 - 0.0082 16.1 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain Prefoldin_2 PF01920.20 CAR28233.1 - 2.4e-13 49.9 8.3 2.7e-13 49.8 8.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.11 CAR28233.1 - 0.2 12.2 4.2 1.8 9.2 0.8 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF5320 PF17253.2 CAR28233.1 - 0.49 11.5 1.6 1.7 9.7 0.0 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5320) ATP12 PF07542.11 CAR28234.1 - 1.6e-34 118.8 0.0 2.7e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Glyco_transf_34 PF05637.12 CAR28236.1 - 8.6e-53 179.5 0.0 1.1e-52 179.1 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Galactosyl_T PF01762.21 CAR28236.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase Prefoldin_3 PF13758.6 CAR28236.1 - 0.11 12.5 0.2 0.22 11.6 0.2 1.4 1 0 0 1 1 1 0 Prefoldin subunit MFS_1 PF07690.16 CAR28237.1 - 1e-24 87.1 18.3 1.5e-24 86.6 18.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 CAR28237.1 - 0.0044 17.2 4.5 0.069 13.3 1.6 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3792) DUF63 PF01889.17 CAR28237.1 - 1.1 9.4 5.4 0.31 11.2 0.3 2.3 3 0 0 3 3 3 0 Membrane protein of unknown function DUF63 QueT PF06177.11 CAR28237.1 - 1.4 9.3 8.9 0.2 12.0 1.3 2.7 2 0 0 2 2 2 0 QueT transporter Gon7 PF08738.10 CAR28238.1 - 3.1e-41 139.8 0.1 3.7e-41 139.6 0.1 1.1 1 0 0 1 1 1 1 Gon7 family SSB PF00436.25 CAR28239.1 - 4.8e-20 71.5 0.3 5.8e-20 71.3 0.3 1.1 1 0 0 1 1 1 1 Single-strand binding protein family p47_phox_C PF08944.11 CAR28240.1 - 0.24 10.8 1.4 0.52 9.8 1.4 1.4 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain muHD PF10291.9 CAR28241.1 - 2.8e-66 223.7 0.0 4.6e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Sigma54_activ_2 PF14532.6 CAR28241.1 - 0.09 12.9 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mannosyl_trans3 PF11051.8 CAR28242.1 - 3.4e-75 252.9 0.0 5.3e-75 252.3 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Thioredoxin PF00085.20 CAR28244.1 - 7.7e-27 93.3 0.0 9e-27 93.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CAR28244.1 - 3.9e-06 27.1 0.0 0.0077 16.5 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 CAR28244.1 - 5e-06 26.3 0.0 5.7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CAR28244.1 - 1.1e-05 25.8 0.1 0.00023 21.6 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 CAR28244.1 - 4.4e-05 23.2 0.1 0.0058 16.4 0.1 2.1 1 1 1 2 2 2 2 Redoxin TraF PF13728.6 CAR28244.1 - 0.00011 22.1 0.0 0.00013 21.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 CAR28244.1 - 0.0045 17.2 0.1 0.0085 16.3 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin Phosducin PF02114.16 CAR28244.1 - 0.0084 15.1 0.0 0.0092 14.9 0.0 1.0 1 0 0 1 1 1 1 Phosducin AhpC-TSA PF00578.21 CAR28244.1 - 0.0087 16.0 0.0 0.021 14.7 0.0 1.6 1 1 1 2 2 2 1 AhpC/TSA family TMEM223 PF14640.6 CAR28245.1 - 0.0055 16.9 0.1 0.027 14.6 0.1 2.2 1 1 0 1 1 1 1 Transmembrane protein 223 UbiA PF01040.18 CAR28246.1 - 3e-45 154.5 12.7 4.1e-45 154.1 12.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family MDD_C PF18376.1 CAR28247.1 - 1e-67 227.5 0.0 1.4e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CAR28247.1 - 2.6e-10 40.4 1.7 7.8e-10 38.8 1.7 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain WD40 PF00400.32 CAR28248.1 - 1.7e-48 161.5 14.2 1.3e-08 35.4 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CAR28248.1 - 4e-29 100.7 13.5 4e-29 100.7 13.5 2.7 2 0 0 2 2 2 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CAR28248.1 - 3.4e-15 56.1 0.0 2.6e-05 24.4 0.0 6.0 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR28248.1 - 1.1e-05 24.4 1.7 0.4 9.3 0.0 4.2 2 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CAR28248.1 - 0.00073 18.9 0.0 0.41 9.9 0.0 3.5 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 CAR28248.1 - 0.015 14.3 4.3 0.58 9.1 0.0 4.1 4 1 2 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Tox-ODYAM1 PF15642.6 CAR28248.1 - 6.2 5.7 13.9 11 4.9 13.9 1.3 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Csm1 PF12539.8 CAR28249.1 - 6e-24 84.5 0.0 1e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Csm1_N PF18504.1 CAR28249.1 - 1.2e-22 80.0 7.9 1.2e-22 80.0 7.9 1.7 2 0 0 2 2 2 1 Csm1 N-terminal domain Spc24 PF08286.11 CAR28249.1 - 0.0043 17.3 0.7 0.0059 16.8 0.7 1.3 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 DUF3584 PF12128.8 CAR28249.1 - 0.02 12.4 1.4 0.023 12.3 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF16 PF01519.16 CAR28249.1 - 0.037 14.5 1.7 0.07 13.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DLP_helical PF18709.1 CAR28249.1 - 0.073 12.3 0.6 0.081 12.1 0.6 1.1 1 0 0 1 1 1 0 Dynamin-like helical domain Cluap1 PF10234.9 CAR28249.1 - 1.8 7.9 7.9 2.7 7.3 4.8 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 zf-LYAR PF08790.11 CAR28250.1 - 5.8e-14 51.7 6.4 1.2e-13 50.7 6.4 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger PPL5 PF18168.1 CAR28250.1 - 0.029 13.7 2.8 0.034 13.5 2.8 1.1 1 0 0 1 1 1 0 Prim-pol family 5 zf-C2H2_jaz PF12171.8 CAR28250.1 - 0.032 14.5 4.4 0.16 12.3 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding XPA_N PF01286.18 CAR28250.1 - 0.068 13.2 3.4 2.3 8.3 0.1 2.5 2 0 0 2 2 2 0 XPA protein N-terminal DUF3306 PF11748.8 CAR28250.1 - 0.076 13.9 5.6 0.11 13.4 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) zf-C2H2_4 PF13894.6 CAR28250.1 - 0.13 13.1 5.5 1 10.4 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PTPRCAP PF15713.5 CAR28250.1 - 0.17 12.2 4.0 0.19 12.0 4.0 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated zf_UBZ PF18439.1 CAR28250.1 - 0.24 11.0 1.6 15 5.3 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Trypan_PARP PF05887.11 CAR28250.1 - 0.45 10.5 7.6 0.63 10.0 7.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ndc1_Nup PF09531.10 CAR28250.1 - 0.46 9.1 3.9 0.47 9.1 3.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-met PF12874.7 CAR28250.1 - 0.96 9.9 5.0 6.8 7.2 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CAR28250.1 - 1.6 9.3 5.9 9.7 6.8 2.3 2.8 2 1 0 2 2 2 0 Zinc-finger double domain RNHCP PF12647.7 CAR28250.1 - 3.8 7.6 7.2 2.7 8.0 2.8 2.1 1 1 1 2 2 2 0 RNHCP domain Presenilin PF01080.17 CAR28250.1 - 4 6.1 4.9 3.9 6.1 4.9 1.1 1 0 0 1 1 1 0 Presenilin Cofilin_ADF PF00241.20 CAR28251.1 - 1.3e-19 70.1 0.0 2.3e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 CAR28251.1 - 1.9e-16 59.4 0.5 4.4e-16 58.2 0.5 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR28251.1 - 3.2e-13 49.3 0.3 6.3e-13 48.4 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR28251.1 - 2.2e-07 30.4 0.0 4.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Flocculin_t3 PF13928.6 CAR28252.1 - 3.4e-21 75.5 157.6 6.2e-06 26.6 12.6 20.2 14 5 4 18 18 18 8 Flocculin type 3 repeat Rib_hydrolayse PF02267.17 CAR28252.1 - 0.18 11.2 6.9 11 5.3 0.1 4.7 6 0 0 6 6 6 0 ADP-ribosyl cyclase DUF866 PF05907.13 CAR28253.1 - 8.4e-46 155.7 1.8 1.1e-45 155.3 1.8 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-PHD-like PF15446.6 CAR28253.1 - 0.068 12.8 2.0 0.07 12.7 0.6 1.7 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Yippee-Mis18 PF03226.14 CAR28253.1 - 0.55 10.5 5.9 1.1 9.5 2.3 2.5 1 1 2 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Trm112p PF03966.16 CAR28255.1 - 1.6e-21 76.6 0.2 2.2e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 Trm112p-like protein Pkinase PF00069.25 CAR28256.1 - 3.5e-77 259.3 0.0 5.8e-77 258.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28256.1 - 3.7e-31 108.4 0.0 1.7e-29 102.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR28256.1 - 9.7e-09 34.9 0.0 4.3e-05 23.0 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CAR28256.1 - 0.00018 20.4 0.0 0.00018 20.4 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 CAR28256.1 - 0.07 12.7 0.1 0.26 10.9 0.1 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MutS_V PF00488.21 CAR28257.1 - 1.9e-63 213.9 0.0 2e-62 210.6 0.0 2.3 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CAR28257.1 - 1.7e-32 113.2 0.5 5.4e-32 111.6 0.1 2.1 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CAR28257.1 - 1.2e-28 99.6 0.1 3.2e-28 98.2 0.1 1.8 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 CAR28257.1 - 4.1e-06 27.0 0.2 4.1e-06 27.0 0.2 2.5 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 CAR28257.1 - 0.00041 20.6 0.0 0.00041 20.6 0.0 3.2 4 0 0 4 4 4 1 MutS domain II Myc_N PF01056.18 CAR28257.1 - 0.082 12.8 7.5 0.15 11.9 7.5 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Stn1 PF10451.9 CAR28257.1 - 0.13 11.2 1.3 0.28 10.1 1.3 1.5 1 0 0 1 1 1 0 Telomere regulation protein Stn1 PBP1_TM PF14812.6 CAR28257.1 - 4.5 7.7 7.1 10 6.6 7.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Not1 PF04054.15 CAR28258.1 - 5.9e-130 433.4 3.8 5.9e-130 433.4 3.8 3.0 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 CNOT1_HEAT_N PF16419.5 CAR28258.1 - 8e-89 297.2 1.8 8e-89 297.2 1.8 2.6 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_CAF1_bind PF16415.5 CAR28258.1 - 3.9e-86 288.1 3.1 3.9e-86 288.1 3.1 2.4 2 1 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 CAR28258.1 - 7.4e-44 149.2 0.1 2.9e-43 147.3 0.1 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CAR28258.1 - 8.4e-39 132.8 1.6 8.4e-39 132.8 1.6 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 CAR28258.1 - 8.6e-13 48.6 0.3 8.6e-13 48.6 0.3 3.1 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Haem_oxygenas_2 PF14518.6 CAR28258.1 - 0.036 13.8 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Iron-containing redox enzyme DUF1896 PF08989.10 CAR28258.1 - 0.058 13.5 1.5 3.7 7.6 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1896) tRNA-synt_2_TM PF16995.5 CAR28258.1 - 4.9 6.8 6.9 18 5.0 0.3 2.5 2 0 0 2 2 2 0 Transmembrane region of lysyl-tRNA synthetase CDC50 PF03381.15 CAR28259.1 - 2.8e-91 305.9 1.4 3.3e-91 305.7 1.4 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Mso1_Sec1_bdg PF14475.6 CAR28260.1 - 3e-15 55.5 0.0 6.1e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Sacchrp_dh_C PF16653.5 CAR28261.1 - 1.2e-91 307.5 0.0 1.6e-91 307.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CAR28261.1 - 1.6e-26 93.1 0.0 2.3e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CAR28261.1 - 2e-08 34.4 0.1 4.8e-08 33.2 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 CAR28261.1 - 2.6e-06 27.5 0.0 4.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_3 PF03447.16 CAR28261.1 - 0.0086 16.7 0.1 0.025 15.2 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CAR28261.1 - 0.082 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Y_phosphatase2 PF03162.13 CAR28262.1 - 1.4e-35 122.3 1.4 4.5e-34 117.4 1.4 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family NTF2 PF02136.20 CAR28263.1 - 8.9e-23 81.1 0.7 1.8e-22 80.1 0.2 1.8 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Red1 PF07964.11 CAR28263.1 - 4.6 5.4 32.6 7.4 4.7 32.6 1.2 1 0 0 1 1 1 0 Rec10 / Red1 CAF1 PF04857.20 CAR28264.1 - 1.9e-14 53.6 5.9 8.5e-08 31.7 0.1 3.0 2 1 1 3 3 3 2 CAF1 family ribonuclease DUF2722 PF10846.8 CAR28264.1 - 0.00072 18.6 1.6 0.00072 18.6 1.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Mob1_phocein PF03637.17 CAR28264.1 - 0.037 14.1 0.1 0.094 12.7 0.1 1.6 1 0 0 1 1 1 0 Mob1/phocein family GN3L_Grn1 PF08701.11 CAR28264.1 - 0.16 12.1 5.9 0.34 11.1 5.9 1.5 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase He_PIG PF05345.12 CAR28264.1 - 0.17 12.1 0.1 0.51 10.6 0.1 1.8 1 0 0 1 1 1 0 Putative Ig domain AAA_26 PF13500.6 CAR28264.1 - 0.2 11.4 2.9 0.39 10.5 2.9 1.4 1 0 0 1 1 1 0 AAA domain eIF_4EBP PF05456.11 CAR28264.1 - 0.58 10.1 4.7 1.6 8.7 4.7 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Roughex PF06020.11 CAR28264.1 - 3.5 6.6 5.4 5.6 6.0 5.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Inj_translocase PF16928.5 CAR28264.1 - 7.2 6.0 21.5 0.2 11.1 13.2 2.2 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome NGP1NT PF08153.12 CAR28265.1 - 1e-50 171.2 2.4 2e-50 170.3 2.4 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CAR28265.1 - 2.3e-17 63.1 0.0 9.5e-14 51.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR28265.1 - 2.7e-05 23.8 0.1 0.0001 21.9 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 CAR28265.1 - 0.0051 16.3 0.1 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CAR28265.1 - 0.019 14.9 0.0 0.059 13.3 0.0 1.9 1 1 0 1 1 1 0 RsgA GTPase GTP_EFTU PF00009.27 CAR28265.1 - 0.025 14.1 0.3 3.1 7.3 0.0 3.2 1 1 2 4 4 4 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CAR28265.1 - 0.053 13.6 6.2 0.73 9.9 0.0 3.7 3 2 1 4 4 4 0 Dynamin family RRM_1 PF00076.22 CAR28266.1 - 0.00078 19.2 0.0 0.099 12.5 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CPSF100_C PF13299.6 CAR28266.1 - 0.61 10.2 17.4 0.52 10.5 8.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 CAR28266.1 - 1.7 8.4 28.3 2.1 8.1 14.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LMBR1 PF04791.16 CAR28266.1 - 2.2 7.1 8.5 3.4 6.5 8.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DAG_kinase_N PF14513.6 CAR28266.1 - 3.4 7.8 15.7 5.8 7.1 7.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus CDC45 PF02724.14 CAR28266.1 - 6.3 5.0 31.8 0.12 10.7 17.0 2.1 2 0 0 2 2 2 0 CDC45-like protein ABC2_membrane PF01061.24 CAR28267.1 - 3.2e-84 281.6 56.3 8e-45 152.8 22.9 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CAR28267.1 - 2.9e-40 138.0 0.0 1e-18 68.2 0.0 3.1 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 CAR28267.1 - 1.3e-34 117.9 1.5 7.7e-30 102.7 0.1 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CAR28267.1 - 1e-16 61.3 0.0 3.3e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CAR28267.1 - 1.1e-07 32.4 0.1 0.00012 22.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CAR28267.1 - 2.1e-07 30.7 0.1 2.2e-05 24.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CAR28267.1 - 2.2e-06 28.2 0.0 0.00057 20.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CAR28267.1 - 7e-06 26.0 0.0 0.0005 20.0 0.0 2.7 3 0 0 3 3 2 1 RsgA GTPase AAA_29 PF13555.6 CAR28267.1 - 0.00019 21.1 0.5 0.0077 16.0 0.1 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_33 PF13671.6 CAR28267.1 - 0.00019 21.6 0.0 0.066 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CAR28267.1 - 0.00029 20.8 0.1 0.21 11.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CAR28267.1 - 0.00053 20.3 0.0 0.26 11.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CAR28267.1 - 0.00055 19.4 0.0 0.034 13.6 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 CAR28267.1 - 0.0016 18.4 0.0 2.3 8.1 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 CAR28267.1 - 0.0028 18.2 0.2 0.04 14.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 CAR28267.1 - 0.013 15.1 3.8 0.78 9.3 0.5 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 CAR28267.1 - 0.014 15.6 2.1 0.25 11.6 0.2 2.5 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 CAR28267.1 - 0.016 14.6 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_30 PF13604.6 CAR28267.1 - 0.024 14.3 0.6 3.1 7.5 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CAR28267.1 - 0.053 14.0 0.1 14 6.1 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 CAR28267.1 - 0.069 11.8 0.0 12 4.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 CAR28267.1 - 0.073 13.5 0.2 3.5 8.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CAR28267.1 - 0.082 12.9 0.2 2 8.4 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 CAR28267.1 - 0.085 12.7 0.0 16 5.2 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase IstB_IS21 PF01695.17 CAR28267.1 - 0.12 12.1 0.0 8.6 6.1 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Zip PF02535.22 CAR28268.1 - 2.6e-56 191.3 0.1 3e-56 191.1 0.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2157 PF09925.9 CAR28268.1 - 0.13 12.0 1.8 9.7 6.0 0.1 2.9 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) SSF PF00474.17 CAR28269.1 - 2.4e-21 76.1 21.8 3.6e-21 75.5 21.8 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family FMO-like PF00743.19 CAR28270.1 - 4.3e-30 104.6 0.5 8.6e-18 64.0 0.0 2.8 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CAR28270.1 - 1.7e-14 53.8 0.0 4.9e-11 42.4 0.0 2.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR28270.1 - 6.2e-13 48.7 0.0 3.1e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CAR28270.1 - 3.8e-06 26.3 0.0 0.0012 18.1 0.0 3.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CAR28270.1 - 5.3e-06 26.3 0.0 0.21 11.1 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CAR28270.1 - 0.00047 20.2 0.1 0.13 12.3 0.1 4.1 3 2 1 4 4 4 1 FAD-NAD(P)-binding HI0933_like PF03486.14 CAR28270.1 - 0.079 11.6 0.0 3.6 6.2 0.0 2.6 2 1 1 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.6 CAR28270.1 - 0.098 12.9 1.1 1.3 9.3 0.0 3.1 4 0 0 4 4 4 0 NAD(P)-binding Rossmann-like domain Bac_luciferase PF00296.20 CAR28271.1 - 1.5e-49 169.1 0.0 2.4e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.26 CAR28272.1 - 1.8e-06 27.9 0.0 3.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR28272.1 - 0.00039 20.3 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CAR28272.1 - 0.00043 21.4 0.0 0.00086 20.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sugar_tr PF00083.24 CAR28273.1 - 6.8e-82 275.7 22.2 8.9e-82 275.3 22.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR28273.1 - 1.7e-24 86.5 32.3 1.7e-24 86.5 32.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR28273.1 - 0.063 11.7 9.0 0.02 13.3 2.7 2.3 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) AA_permease PF00324.21 CAR28274.1 - 1.8e-101 340.1 51.6 2.2e-101 339.9 51.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR28274.1 - 6.6e-28 97.7 53.5 8.2e-28 97.4 53.5 1.1 1 0 0 1 1 1 1 Amino acid permease lci PF12197.8 CAR28274.1 - 0.049 13.4 0.8 0.11 12.3 0.8 1.6 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein Acetyltransf_3 PF13302.7 CAR28275.1 - 5.8e-16 59.4 0.0 8.5e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAR28275.1 - 5.1e-05 23.5 0.0 7.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 CAR28275.1 - 0.0055 16.8 0.0 0.0074 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3873 PF12989.7 CAR28275.1 - 0.081 13.3 0.3 0.18 12.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) AA_permease PF00324.21 CAR28276.1 - 1e-111 373.9 36.0 1.1e-111 373.8 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR28276.1 - 7e-38 130.5 36.1 8.4e-38 130.3 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3098 PF11297.8 CAR28276.1 - 0.074 12.7 0.2 0.074 12.7 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) YwiC PF14256.6 CAR28276.1 - 3.2 8.1 11.8 3.6 7.9 0.4 3.9 3 1 0 3 3 3 0 YwiC-like protein TrbC PF04956.13 CAR28276.1 - 3.2 8.0 17.3 2.4 8.4 2.1 4.3 4 0 0 4 4 4 0 TrbC/VIRB2 family OPT PF03169.15 CAR28277.1 - 2.7e-139 465.6 44.3 3.2e-139 465.4 44.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 CAR28277.1 - 0.66 9.3 3.0 1.6 8.0 3.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF2208 PF09973.9 CAR28277.1 - 0.75 9.4 6.4 1.5 8.4 0.1 3.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Phage_holin_3_6 PF07332.11 CAR28277.1 - 4.3 7.4 8.9 20 5.3 8.9 2.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Flocculin PF00624.18 CAR28278.1 - 6.3e-290 935.3 796.7 2.8e-11 43.5 14.4 38.1 37 1 1 38 38 38 32 Flocculin repeat GLEYA PF10528.9 CAR28278.1 - 3e-24 85.2 1.5 3e-24 85.2 1.5 6.7 6 0 0 6 6 6 1 GLEYA domain PA14 PF07691.12 CAR28278.1 - 4.7e-13 49.2 0.8 1.2e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 PA14 domain BAALC_N PF06989.12 CAR28278.1 - 0.00014 22.1 340.7 1.5 9.2 1.7 34.3 34 1 0 34 34 34 27 BAALC N-terminus AA_permease_2 PF13520.6 CAR28279.1 - 1.8e-50 172.0 51.0 2.3e-50 171.7 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAR28279.1 - 6.5e-18 64.6 41.9 8.6e-18 64.2 41.9 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 CAR28280.1 - 2.5e-16 59.6 16.0 3.8e-16 59.0 16.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Nucleoside_tran PF01733.18 CAR28280.1 - 0.21 10.9 7.7 1.2 8.5 0.4 2.6 2 1 1 3 3 3 0 Nucleoside transporter TauD PF02668.16 CAR28281.1 - 4e-60 203.9 0.9 4e-60 203.9 0.9 1.4 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family RrnaAD PF00398.20 CAR28282.1 - 1.7e-69 233.9 0.0 2e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CAR28282.1 - 9.3e-06 26.3 0.0 2.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CAR28282.1 - 0.00055 19.7 0.0 0.00083 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 CAR28282.1 - 0.00055 20.5 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CAR28282.1 - 0.00088 18.6 0.0 0.0028 17.0 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 CAR28282.1 - 0.0031 16.7 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_23 PF13489.6 CAR28282.1 - 0.0091 15.9 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 CAR28282.1 - 0.0096 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 CAR28282.1 - 0.01 16.6 0.0 0.02 15.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CAR28282.1 - 0.036 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 CAR28282.1 - 0.057 12.7 0.0 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PI-PLC-X PF00388.19 CAR28284.1 - 4e-48 162.7 0.0 1e-47 161.4 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CAR28284.1 - 1.1e-38 132.1 1.2 2.4e-38 131.0 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_7 PF13499.6 CAR28284.1 - 6.8e-10 39.3 1.1 0.00063 20.1 0.2 3.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_like PF09279.11 CAR28284.1 - 2.9e-07 30.9 0.1 6.5e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 CAR28284.1 - 3.7e-07 29.2 2.5 1.9e-06 27.0 0.1 3.2 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 CAR28284.1 - 5.4e-05 22.5 0.3 0.00015 21.1 0.3 1.8 1 0 0 1 1 1 1 EF hand C2 PF00168.30 CAR28284.1 - 0.0005 20.3 0.0 0.0019 18.5 0.0 2.0 2 0 0 2 2 2 1 C2 domain EF-hand_6 PF13405.6 CAR28284.1 - 0.002 17.9 0.3 0.002 17.9 0.3 3.5 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 CAR28284.1 - 0.05 13.4 0.9 12 5.8 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_10 PF14788.6 CAR28284.1 - 0.28 11.1 1.8 0.58 10.1 0.3 2.4 2 0 0 2 2 2 0 EF hand KAR9 PF08580.10 CAR28285.1 - 1.4e-48 166.0 11.4 1.4e-48 166.0 11.4 2.0 1 1 1 2 2 2 2 Yeast cortical protein KAR9 Rx_N PF18052.1 CAR28285.1 - 0.5 10.7 5.3 0.99 9.7 0.0 3.3 2 1 0 2 2 2 0 Rx N-terminal domain Prominin PF05478.11 CAR28285.1 - 2.1 6.2 7.5 1 7.2 3.6 2.0 1 1 1 2 2 2 0 Prominin RICH PF05062.12 CAR28285.1 - 5.8 7.3 9.7 1.3 9.5 0.1 2.7 2 0 0 2 2 2 0 RICH domain ABC_membrane PF00664.23 CAR28286.1 - 1.1e-57 195.8 3.2 1.4e-57 195.4 3.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CAR28286.1 - 8.3e-34 117.0 0.0 2.7e-33 115.4 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CAR28286.1 - 0.00086 18.8 0.0 0.029 13.8 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAR28286.1 - 0.012 15.3 0.0 0.047 13.4 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CAR28286.1 - 0.038 14.4 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CAR28286.1 - 0.046 14.1 0.0 0.31 11.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 CAR28286.1 - 0.048 12.5 0.1 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 CAR28286.1 - 0.057 13.2 0.0 0.94 9.2 0.0 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.14 CAR28286.1 - 0.063 13.3 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 CAR28286.1 - 0.099 12.4 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR28286.1 - 0.11 12.8 0.1 0.89 9.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain ATP-synt_Eps PF04627.13 CAR28287.1 - 1.3e-20 73.1 1.5 1.4e-20 72.9 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain DNA_pol_phi PF04931.13 CAR28288.1 - 5.6e-223 742.3 30.4 8.9e-223 741.7 30.4 1.3 1 0 0 1 1 1 1 DNA polymerase phi DUF664 PF04978.12 CAR28288.1 - 0.13 12.6 2.2 1 9.8 2.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF664) CAF1C_H4-bd PF12265.8 CAR28289.1 - 1.6e-22 79.5 0.3 4.6e-22 78.0 0.3 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CAR28289.1 - 6.9e-16 58.3 0.2 0.0022 18.8 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Frtz PF11768.8 CAR28289.1 - 0.016 13.5 0.0 0.091 11.1 0.0 1.8 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Kelch_4 PF13418.6 CAR28290.1 - 3.8e-28 97.2 11.1 5.1e-07 29.6 0.7 6.8 5 3 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 CAR28290.1 - 2.1e-25 88.5 9.4 1.6e-07 31.5 0.0 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain DUF4110 PF13422.6 CAR28290.1 - 2.5e-24 85.2 0.1 2.5e-24 85.2 0.1 4.5 4 3 1 5 5 5 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 CAR28290.1 - 7.6e-17 60.9 11.5 7.7e-06 26.0 0.2 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CAR28290.1 - 1.8e-12 46.9 2.7 0.016 15.2 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 CAR28290.1 - 7.7e-10 38.2 6.7 0.00053 19.5 0.2 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 CAR28290.1 - 5.3e-09 35.7 15.2 0.082 12.9 0.4 5.4 6 0 0 6 6 6 4 Kelch motif PGM_PMM_I PF02878.16 CAR28291.1 - 1.6e-14 53.8 0.0 9.8e-08 31.8 0.0 2.5 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CAR28291.1 - 2.9e-10 40.2 0.2 9.6e-10 38.5 0.3 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 CAR28291.1 - 0.0053 17.3 0.1 0.04 14.5 0.0 2.6 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF4454 PF14628.6 CAR28291.1 - 0.031 14.1 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4454) Mitochondr_Som1 PF11093.8 CAR28292.1 - 4e-13 49.2 0.4 5.3e-13 48.8 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 AIF-MLS PF14962.6 CAR28292.1 - 0.03 14.3 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence HIM1 PF08732.10 CAR28293.1 - 1.2e-64 216.9 0.0 1.9e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 HIM1 Mac-1 PF09028.10 CAR28293.1 - 0.012 14.7 0.1 0.023 13.8 0.1 1.4 1 0 0 1 1 1 0 Mac 1 BOP1NT PF08145.12 CAR28294.1 - 6.5e-105 350.7 6.1 1.1e-104 350.0 6.1 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CAR28294.1 - 2.5e-23 81.9 6.7 2e-09 37.9 0.2 6.7 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR28294.1 - 3.2e-08 33.7 0.4 0.00042 20.6 0.0 4.1 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RRN3 PF05327.11 CAR28294.1 - 0.8 8.2 9.8 1.4 7.4 9.8 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Swi3 PF07962.12 CAR28295.1 - 1.2e-25 89.3 0.2 2.2e-25 88.4 0.2 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Nucleoporin_FG PF13634.6 CAR28296.1 - 2.9e-59 197.9 376.4 1.3e-13 51.6 33.8 14.0 4 3 9 14 14 14 12 Nucleoporin FG repeat region Nucleoporin2 PF04096.14 CAR28296.1 - 2.2e-38 131.7 0.0 4.2e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase PWWP PF00855.17 CAR28297.1 - 5.4e-25 87.6 1.2 5.4e-25 87.6 1.2 2.6 3 0 0 3 3 3 1 PWWP domain YL1 PF05764.13 CAR28297.1 - 0.0012 19.0 18.1 0.002 18.3 18.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 CAR28297.1 - 0.077 11.3 13.0 0.1 10.9 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 CAR28297.1 - 0.62 10.3 6.8 0.92 9.7 6.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.17 CAR28297.1 - 1.6 7.4 8.0 2.2 7.0 8.0 1.1 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 CAR28297.1 - 6.1 5.6 9.2 41 2.9 7.1 2.2 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 SRF-TF PF00319.18 CAR28298.1 - 2.9e-21 74.7 0.2 4.4e-21 74.1 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) SRF-TF PF00319.18 CAR28299.1 - 5.1e-22 77.1 0.4 4.3e-21 74.1 0.0 2.0 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) NDK PF00334.19 CAR28300.1 - 2.8e-54 182.8 0.0 3.2e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase CinA PF02464.17 CAR28301.1 - 0.037 13.6 0.3 0.047 13.2 0.3 1.1 1 0 0 1 1 1 0 Competence-damaged protein Aldo_ket_red PF00248.21 CAR28302.1 - 3.4e-47 161.1 0.0 4.1e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Bap31 PF05529.12 CAR28303.1 - 5.7e-25 87.8 4.5 8.8e-25 87.1 4.5 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CAR28303.1 - 0.0012 18.8 3.4 0.0019 18.2 3.4 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Sec2p PF06428.11 CAR28303.1 - 0.0033 17.4 1.6 0.0052 16.7 1.6 1.3 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Csm1_N PF18504.1 CAR28303.1 - 0.14 12.6 2.3 0.25 11.7 2.3 1.4 1 0 0 1 1 1 0 Csm1 N-terminal domain PC4 PF02229.16 CAR28304.1 - 2.2e-22 78.4 0.1 3.9e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) CorA PF01544.18 CAR28305.1 - 2.6e-37 128.8 4.4 3.8e-20 72.4 0.1 3.3 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Herpes_LP PF03363.13 CAR28305.1 - 0.035 13.9 2.8 0.1 12.4 2.8 1.8 1 0 0 1 1 1 0 Herpesvirus leader protein HMA PF00403.26 CAR28306.1 - 3.6e-13 49.7 0.0 6.9e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 CAR28306.1 - 2.9e-07 30.7 0.0 1.5e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF3810 PF12725.7 CAR28307.1 - 0.024 14.0 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF4391 PF14335.6 CAR28307.1 - 0.27 10.9 1.2 0.4 10.4 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) zf-C2H2 PF00096.26 CAR28308.1 - 8.7e-11 41.7 13.0 2.7e-06 27.5 3.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR28308.1 - 2e-08 34.3 18.7 5.8e-07 29.7 2.8 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR28308.1 - 4.9e-08 33.2 13.3 0.0014 19.3 3.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CAR28308.1 - 2.2e-06 27.8 12.1 0.0046 17.2 0.9 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CAR28308.1 - 0.00015 21.7 9.5 0.012 15.6 0.5 2.9 3 0 0 3 3 3 2 BED zinc finger zf-met PF12874.7 CAR28308.1 - 0.031 14.7 7.7 1.3 9.5 2.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type GAGA PF09237.11 CAR28308.1 - 0.043 13.6 1.8 0.87 9.4 0.2 2.5 1 1 1 2 2 2 0 GAGA factor zf-C2H2_2 PF12756.7 CAR28308.1 - 0.067 13.5 7.5 0.88 9.9 1.9 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 CAR28308.1 - 0.11 12.7 4.2 0.19 12.1 4.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CAR28308.1 - 0.12 12.2 13.4 0.91 9.3 0.5 3.0 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 CAR28308.1 - 0.12 13.0 1.9 0.7 10.6 1.9 2.1 1 1 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 CAR28308.1 - 0.14 11.8 6.1 0.45 10.2 0.5 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 CAR28308.1 - 0.21 11.7 14.9 1.4 9.0 2.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HE PF16278.5 CAR28308.1 - 0.29 11.6 10.2 0.69 10.4 1.1 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 CAR28308.1 - 0.34 11.1 2.6 7.9 6.7 0.2 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger zf-LYAR PF08790.11 CAR28308.1 - 0.9 9.5 3.4 15 5.6 0.4 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF629 PF04780.12 CAR28308.1 - 2.5 6.5 8.9 1.9 7.0 1.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_11 PF16622.5 CAR28308.1 - 6.3 6.7 6.1 6.6 6.6 0.6 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Pkinase PF00069.25 CAR28309.1 - 7.2e-40 137.0 0.0 1.6e-33 116.2 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28309.1 - 2.4e-20 72.9 0.0 3e-16 59.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CAR28309.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CAR28309.1 - 0.041 13.5 0.1 0.94 9.1 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CAR28309.1 - 0.052 12.9 0.0 0.24 10.7 0.0 1.9 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 CAR28309.1 - 0.11 11.3 0.0 0.29 9.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Rhodanese PF00581.20 CAR28310.1 - 6.6e-10 39.5 0.0 1.4e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_S24 PF00717.23 CAR28311.1 - 3.6e-07 30.0 0.0 6.8e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CAR28311.1 - 0.055 13.3 0.0 0.24 11.2 0.0 1.9 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 SBF_like PF13593.6 CAR28312.1 - 1.7e-113 379.1 12.2 2e-113 378.9 12.2 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 CAR28312.1 - 2.9e-10 40.2 3.3 6.4e-10 39.0 3.3 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family DUF805 PF05656.14 CAR28312.1 - 6.5 7.2 8.7 0.66 10.4 2.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Actin PF00022.19 CAR28313.1 - 1.1e-19 70.4 0.1 1.3e-18 66.8 0.1 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 CAR28313.1 - 8.5e-05 22.9 0.1 0.0002 21.7 0.1 1.6 1 1 0 1 1 1 1 Cell division protein FtsA MreB_Mbl PF06723.13 CAR28313.1 - 0.00041 19.3 0.2 0.17 10.6 0.1 2.9 3 0 0 3 3 3 2 MreB/Mbl protein Histone PF00125.24 CAR28314.1 - 3.4e-37 127.7 9.0 3.4e-37 127.7 9.0 1.9 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CAR28314.1 - 0.0027 17.8 0.1 0.0063 16.6 0.1 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CAR28314.1 - 0.032 14.6 0.1 0.064 13.6 0.1 1.5 1 0 0 1 1 1 0 CENP-S protein FCH PF00611.23 CAR28315.1 - 5.6e-13 49.0 0.4 2.1e-12 47.1 0.2 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 CAR28315.1 - 0.00025 20.9 0.1 0.0005 19.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CAR28315.1 - 0.0099 15.5 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PBS_linker_poly PF00427.21 CAR28315.1 - 0.14 12.2 6.4 1.8 8.6 2.1 2.6 2 0 0 2 2 2 0 Phycobilisome Linker polypeptide Eisosome1 PF12757.7 CAR28316.1 - 1.4e-29 102.9 4.0 1.4e-29 102.9 4.0 5.3 3 2 2 5 5 5 1 Eisosome protein 1 AAA_assoc_2 PF16193.5 CAR28316.1 - 0.068 13.5 2.2 0.41 11.0 0.4 3.4 3 0 0 3 3 3 0 AAA C-terminal domain Frag1 PF10277.9 CAR28317.1 - 4.7e-74 248.6 20.6 5.5e-74 248.4 20.6 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DASH_Ask1 PF08655.10 CAR28318.1 - 1.1e-24 86.0 0.0 1.8e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 CPSF73-100_C PF11718.8 CAR28318.1 - 0.066 12.8 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Lyase_aromatic PF00221.19 CAR28318.1 - 0.1 11.3 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Aromatic amino acid lyase ECH_2 PF16113.5 CAR28319.1 - 5.8e-90 302.2 0.0 6.8e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CAR28319.1 - 5.1e-23 81.7 0.0 1e-22 80.7 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase UCH PF00443.29 CAR28320.1 - 6e-41 140.6 0.0 1.3e-40 139.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR28320.1 - 6e-20 72.1 0.9 6.6e-18 65.4 0.0 3.1 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CAR28320.1 - 4e-19 68.7 5.9 4e-19 68.7 5.9 3.1 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 CAR28320.1 - 9.1e-10 38.3 0.1 2.1e-05 24.3 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP_var PF17807.1 CAR28320.1 - 7.4e-09 35.2 13.9 1.9e-07 30.7 7.0 3.3 2 1 0 2 2 2 2 Variant UBP zinc finger zf-Mss51 PF13824.6 CAR28320.1 - 0.022 14.9 5.8 5.3 7.2 1.5 3.8 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 CpXC PF14353.6 CAR28320.1 - 0.65 10.0 5.1 2.7 8.0 1.1 3.4 3 1 0 3 3 3 0 CpXC protein Wtap PF17098.5 CAR28321.1 - 1.3e-06 28.4 14.5 1.3e-06 28.4 14.5 2.2 1 1 1 2 2 2 1 WTAP/Mum2p family DUF1569 PF07606.11 CAR28321.1 - 0.0066 16.5 0.3 0.15 12.1 0.2 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1569) Phytochelatin PF05023.14 CAR28321.1 - 0.15 11.3 2.0 0.11 11.7 0.2 1.6 2 0 0 2 2 2 0 Phytochelatin synthase Prismane PF03063.20 CAR28321.1 - 0.27 9.9 2.4 0.35 9.5 2.4 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Cnn_1N PF07989.11 CAR28321.1 - 0.31 11.2 18.4 0.52 10.5 0.3 4.4 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 KfrA_N PF11740.8 CAR28321.1 - 0.35 11.6 6.9 18 6.0 0.1 3.3 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term FlaC_arch PF05377.11 CAR28321.1 - 1 9.8 16.7 7.9 7.0 1.9 4.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DAHP_synth_1 PF00793.20 CAR28322.1 - 1.4e-106 355.4 0.0 1.7e-106 355.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Cellulase PF00150.18 CAR28323.1 - 2.6e-13 50.1 3.4 2.6e-13 50.1 3.4 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_L7Ae PF01248.26 CAR28324.1 - 5.8e-28 96.5 0.5 7.7e-28 96.1 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CAR28324.1 - 0.00046 20.3 0.1 0.00088 19.4 0.0 1.4 2 0 0 2 2 2 1 RNase P subunit Pop3 KH_1 PF00013.29 CAR28325.1 - 0.0026 17.5 0.0 0.013 15.3 0.0 2.2 2 1 0 2 2 2 1 KH domain DUF908 PF06012.12 CAR28325.1 - 0.0042 16.6 10.2 0.0062 16.0 10.2 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF908) Adaptin_N PF01602.20 CAR28327.1 - 3.7e-102 342.6 9.5 5.7e-102 341.9 9.5 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 CAR28327.1 - 1.4e-55 187.1 0.6 1.4e-55 187.1 0.6 2.2 2 0 0 2 2 2 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 CAR28327.1 - 9.1e-54 180.9 0.1 3.2e-53 179.1 0.0 2.0 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.6 CAR28327.1 - 2.7e-06 27.7 4.5 0.087 13.2 0.0 5.0 2 1 3 5 5 5 2 HEAT repeats Cnd1 PF12717.7 CAR28327.1 - 8.4e-05 22.7 7.9 0.00076 19.6 0.1 3.3 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Alpha_adaptinC2 PF02883.20 CAR28327.1 - 0.0019 18.5 1.0 0.0095 16.2 0.0 2.3 2 0 0 2 2 2 1 Adaptin C-terminal domain HEAT PF02985.22 CAR28327.1 - 0.0036 17.4 0.5 13 6.4 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat DUF5578 PF17741.1 CAR28327.1 - 0.023 14.1 5.8 1.5 8.2 0.2 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5578) FANCI_S2 PF14676.6 CAR28327.1 - 0.11 12.8 3.4 0.16 12.3 1.6 2.3 2 1 0 2 2 2 0 FANCI solenoid 2 Ribosomal_S2 PF00318.20 CAR28328.1 - 1.6e-23 83.0 1.7 5.3e-14 52.0 0.1 2.4 2 1 1 3 3 3 2 Ribosomal protein S2 40S_SA_C PF16122.5 CAR28328.1 - 0.0013 20.0 12.1 0.0026 19.1 12.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ferric_reduct PF01794.19 CAR28329.1 - 8.8e-19 67.8 10.9 8.8e-19 67.8 10.9 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CAR28329.1 - 0.0019 18.3 0.1 0.0044 17.1 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain AATase PF07247.12 CAR28330.1 - 3.8e-57 194.0 0.5 5.5e-57 193.4 0.5 1.2 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 CAR28330.1 - 6.3e-08 31.7 0.1 0.0076 15.0 0.0 2.2 2 0 0 2 2 2 2 Condensation domain WES_acyltransf PF03007.16 CAR28330.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain zf-ZPR1 PF03367.13 CAR28331.1 - 4.4e-115 380.9 2.7 7.8e-57 191.6 0.1 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 CAR28331.1 - 0.0067 16.4 3.6 0.99 9.5 0.4 2.6 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF2294 PF10057.9 CAR28331.1 - 0.08 13.1 0.4 0.9 9.7 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) OrfB_Zn_ribbon PF07282.11 CAR28331.1 - 0.31 11.0 4.2 8 6.5 0.0 3.1 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-RRPl_C4 PF17026.5 CAR28331.1 - 0.46 10.6 3.1 2.6 8.2 0.8 2.6 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc-ribbons_6 PF07191.12 CAR28331.1 - 0.83 9.7 5.2 0.98 9.4 0.5 2.6 2 1 0 2 2 2 0 zinc-ribbons DNA_RNApol_7kD PF03604.13 CAR28331.1 - 0.83 9.4 3.3 38 4.1 0.1 3.4 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 CAR28331.1 - 3.5 7.5 11.2 8.1 6.3 0.5 4.1 4 0 0 4 4 4 0 zinc-ribbon domain MMR_HSR1_C PF08438.10 CAR28332.1 - 1.4e-34 119.0 0.0 2.2e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CAR28332.1 - 7.7e-20 71.1 0.0 1.6e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR28332.1 - 3.7e-06 26.6 0.1 3.5e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CAR28332.1 - 0.0036 16.9 0.1 2.1 7.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CAR28332.1 - 0.02 14.9 0.1 0.059 13.4 0.1 1.8 1 0 0 1 1 1 0 Dynamin family RsgA_GTPase PF03193.16 CAR28332.1 - 0.04 13.8 0.3 1 9.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 CAR28332.1 - 0.11 11.8 0.1 1.5 8.2 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.27 CAR28332.1 - 0.18 12.3 0.0 0.66 10.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter KTI12 PF08433.10 CAR28332.1 - 0.2 11.0 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TPP_enzyme_N PF02776.18 CAR28333.1 - 1.6e-33 115.8 0.1 2.4e-33 115.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR28333.1 - 1.3e-28 99.5 0.0 1.2e-27 96.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CAR28333.1 - 1.6e-13 50.7 0.0 3e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HEAT PF02985.22 CAR28334.1 - 0.0028 17.8 1.7 1.2 9.6 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat Shugoshin_N PF07558.11 CAR28334.1 - 0.06 13.2 2.0 0.28 11.1 2.0 2.2 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region FAM76 PF16046.5 CAR28334.1 - 0.067 12.5 8.1 0.016 14.6 4.6 1.8 2 0 0 2 2 2 0 FAM76 protein HAUS-augmin3 PF14932.6 CAR28334.1 - 0.32 10.5 18.5 0.053 13.1 12.2 2.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DCB PF16213.5 CAR28334.1 - 0.58 9.8 8.6 0.27 10.9 0.3 3.5 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 JIP_LZII PF16471.5 CAR28334.1 - 0.99 9.6 7.6 2.6 8.3 4.7 3.1 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 CAR28334.1 - 6.7 7.3 24.1 0.8 10.2 17.5 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 CAR28334.1 - 7 5.9 18.2 8 5.7 15.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Thioredoxin PF00085.20 CAR28335.1 - 6.2e-31 106.5 0.3 7e-31 106.3 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CAR28335.1 - 1.5e-07 31.8 0.4 2.9e-07 30.9 0.4 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CAR28335.1 - 3.5e-07 30.1 0.0 4.1e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CAR28335.1 - 7.7e-07 29.4 0.2 1.4e-06 28.5 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CAR28335.1 - 5.9e-06 26.2 0.1 6.9e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAR28335.1 - 1.4e-05 24.9 0.3 2.5e-05 24.0 0.3 1.5 1 1 0 1 1 1 1 Redoxin TraF PF13728.6 CAR28335.1 - 0.00018 21.4 0.1 0.00021 21.2 0.1 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 CAR28335.1 - 0.00051 19.5 0.2 0.00062 19.2 0.2 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family DIM1 PF02966.16 CAR28335.1 - 0.001 18.9 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_7 PF13899.6 CAR28335.1 - 0.041 14.1 0.1 0.071 13.3 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 CAR28335.1 - 0.057 13.4 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 CAR28335.1 - 0.085 13.1 0.1 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin Hydrolase PF00702.26 CAR28336.1 - 6.4e-21 75.6 0.0 9.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAR28336.1 - 3.6e-18 66.7 0.0 4.9e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CAR28336.1 - 1.5e-10 41.3 0.1 5.1e-09 36.2 0.0 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAR28336.1 - 8.9e-08 32.4 0.1 0.012 15.8 0.0 3.0 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 CAR28336.1 - 0.00034 20.2 0.4 0.0023 17.5 0.0 2.3 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Acid_PPase PF12689.7 CAR28336.1 - 0.021 14.7 0.0 0.083 12.7 0.0 1.9 1 1 0 1 1 1 0 Acid Phosphatase Put_Phosphatase PF06888.12 CAR28336.1 - 0.037 13.4 0.1 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase LysR_substrate PF03466.20 CAR28336.1 - 0.083 12.2 0.0 0.45 9.9 0.0 2.1 2 0 0 2 2 2 0 LysR substrate binding domain Yip1 PF04893.17 CAR28337.1 - 2.2e-13 50.3 13.7 3.6e-13 49.6 13.7 1.4 1 0 0 1 1 1 1 Yip1 domain tRNA-synt_1g PF09334.11 CAR28338.1 - 5.3e-92 308.6 1.0 2.9e-90 302.9 1.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CAR28338.1 - 4.2e-22 78.1 0.1 6.7e-09 34.6 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CAR28338.1 - 1.8e-07 30.8 0.1 0.0046 16.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 CAR28338.1 - 0.00077 19.5 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DNA_pol_E_B PF04042.16 CAR28339.1 - 2.1e-41 141.6 0.8 5.5e-41 140.2 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CAR28339.1 - 1.9e-36 125.1 0.0 2.8e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain PS_Dcarbxylase PF02666.15 CAR28340.1 - 6.7e-55 185.7 0.0 1.1e-54 185.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 CAR28340.1 - 1.1e-13 51.3 0.2 1e-11 45.0 0.0 2.7 2 0 0 2 2 2 2 C2 domain zf-C2HC5 PF06221.13 CAR28341.1 - 1.7e-20 72.7 6.3 3.1e-20 71.9 6.3 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Secretin_N_2 PF07655.13 CAR28341.1 - 5.4 7.6 13.2 5.3 7.7 10.8 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Zn_clus PF00172.18 CAR28342.1 - 5e-06 26.5 13.6 1.1e-05 25.4 13.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 CAR28342.1 - 0.00063 19.7 0.6 0.0028 17.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 CAR28342.1 - 0.11 12.8 0.1 11 6.4 0.0 2.8 2 1 0 2 2 2 0 PAS fold Synaptobrevin PF00957.21 CAR28342.1 - 0.32 10.8 5.1 0.77 9.6 5.1 1.6 1 0 0 1 1 1 0 Synaptobrevin PAP_PilO PF06864.12 CAR28342.1 - 0.52 9.1 7.5 0.92 8.3 7.5 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DEAD PF00270.29 CAR28343.1 - 2.8e-38 131.4 0.0 5.1e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR28343.1 - 2.7e-18 66.3 0.0 6.6e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAR28343.1 - 4e-18 65.4 0.1 9.8e-18 64.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CAR28343.1 - 1.9e-05 24.8 0.0 5.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAR28343.1 - 0.078 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Fusion_gly PF00523.18 CAR28343.1 - 0.099 10.9 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Sin_N PF04801.13 CAR28344.1 - 9.2e-19 68.0 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Sin-like protein conserved region IF-2B PF01008.17 CAR28345.1 - 1.8e-69 234.1 0.0 2.1e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family GTP_EFTU PF00009.27 CAR28346.1 - 7.4e-61 205.1 0.1 1.2e-60 204.4 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CAR28346.1 - 1e-24 86.4 0.0 2.5e-24 85.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CAR28346.1 - 3.9e-17 62.1 0.0 9e-09 35.3 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CAR28346.1 - 5.9e-06 26.6 0.0 2e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CAR28346.1 - 0.00017 21.5 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CAR28346.1 - 0.0057 16.7 0.1 0.014 15.4 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gp_dh_C PF02800.20 CAR28346.1 - 0.065 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain GCS PF03074.16 CAR28347.1 - 6e-147 489.8 0.0 7.5e-147 489.5 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase PI3_PI4_kinase PF00454.27 CAR28348.1 - 8.8e-54 182.9 0.0 1.7e-53 182.0 0.0 1.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF2236 PF09995.9 CAR28348.1 - 0.0061 16.8 0.0 0.013 15.7 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) ChAPs PF09295.10 CAR28349.1 - 2.4e-50 171.7 0.8 5e-41 141.0 0.2 2.1 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 CAR28349.1 - 3.5e-05 23.6 1.5 0.0067 16.5 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR28349.1 - 7.8e-05 22.8 0.0 0.0002 21.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 CAR28349.1 - 8e-05 22.3 0.2 0.0003 20.5 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR28349.1 - 0.0004 20.8 0.4 0.0024 18.3 0.2 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR28349.1 - 0.0016 18.5 1.5 0.013 15.7 0.2 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CAR28349.1 - 0.0043 17.3 0.6 0.35 11.4 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAR28349.1 - 0.014 15.5 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Spc24 PF08286.11 CAR28349.1 - 0.047 13.9 0.2 0.2 11.9 0.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_12 PF13424.6 CAR28349.1 - 0.1 12.9 0.3 0.62 10.4 0.3 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Dak2 PF02734.17 CAR28351.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 DAK2 domain Sod_Cu PF00080.20 CAR28353.1 - 2e-17 63.7 0.0 2.9e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MFS_1 PF07690.16 CAR28354.1 - 1.9e-34 119.1 23.6 1.9e-34 119.1 23.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2768 PF10966.8 CAR28354.1 - 0.0039 17.6 1.3 0.018 15.5 1.3 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2768) DUF1129 PF06570.11 CAR28354.1 - 0.17 11.4 0.3 0.41 10.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) MFS_1 PF07690.16 CAR28358.1 - 4e-31 108.2 24.3 4e-30 105.0 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR28358.1 - 2.5e-07 29.9 10.2 4.7e-07 29.0 9.3 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1772 PF08592.11 CAR28358.1 - 0.004 17.5 1.7 1.2 9.4 0.0 3.5 2 1 0 3 3 3 2 Domain of unknown function (DUF1772) Zip PF02535.22 CAR28359.1 - 6.2e-58 196.6 4.8 7.5e-58 196.3 4.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2165 PF09933.9 CAR28359.1 - 1.3 9.1 5.8 0.3 11.1 0.6 2.3 2 1 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) ADH_N_2 PF16884.5 CAR28360.1 - 7.1e-22 77.3 0.0 1.2e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 CAR28360.1 - 5.8e-16 58.6 0.1 8.4e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CRC_subunit PF08624.10 CAR28361.1 - 9.9e-38 129.6 0.1 2.2e-37 128.5 0.1 1.6 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Lectin_leg-like PF03388.13 CAR28362.1 - 1.8e-42 145.3 0.5 2.6e-42 144.7 0.5 1.2 1 0 0 1 1 1 1 Legume-like lectin family DUF5013 PF16405.5 CAR28362.1 - 0.014 15.7 1.9 0.31 11.3 0.1 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF5013) DivIVA PF05103.13 CAR28362.1 - 0.014 15.5 1.1 3.8 7.6 0.0 2.4 2 0 0 2 2 2 0 DivIVA protein DUF5101 PF17031.5 CAR28362.1 - 1.2 9.2 7.4 0.67 10.1 2.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5101) Rdx PF10262.9 CAR28363.1 - 1.9e-25 88.8 0.1 2.5e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 Rdx family RhoGAP PF00620.27 CAR28364.1 - 5.7e-13 49.0 6.3 7e-12 45.4 0.7 2.6 2 0 0 2 2 2 2 RhoGAP domain DEP PF00610.21 CAR28364.1 - 4.2e-11 42.7 0.0 1.3e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 CAR28364.1 - 9.7e-11 41.8 0.0 1.2e-09 38.3 0.0 2.7 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain V-SNARE_C PF12352.8 CAR28366.1 - 6.9e-07 29.5 3.1 1e-06 28.9 3.1 1.3 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CAR28366.1 - 1.5e-05 24.8 0.8 2.5e-05 24.1 0.8 1.3 1 0 0 1 1 1 1 Sec20 Use1 PF09753.9 CAR28366.1 - 0.25 11.0 4.2 0.51 10.0 0.7 2.0 2 0 0 2 2 2 0 Membrane fusion protein Use1 RCC1 PF00415.18 CAR28367.1 - 1.5e-26 92.7 3.8 1.4e-07 32.0 0.1 5.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAR28367.1 - 9.5e-11 41.2 8.9 5.1e-08 32.5 0.0 4.1 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 CAR28367.1 - 0.066 13.1 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain DUF1640 PF07798.11 CAR28368.1 - 2.2e-52 177.7 9.8 2.6e-52 177.4 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF5082 PF16888.5 CAR28368.1 - 0.0027 18.0 6.7 0.55 10.5 0.3 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5082) FTA4 PF13093.6 CAR28368.1 - 0.0047 16.8 8.5 0.0064 16.4 8.4 1.3 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 XhlA PF10779.9 CAR28368.1 - 0.021 15.0 3.2 0.099 12.9 0.1 2.5 2 0 0 2 2 2 0 Haemolysin XhlA DUF2746 PF10874.8 CAR28368.1 - 0.042 14.3 4.5 2.8 8.4 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2746) DUF3584 PF12128.8 CAR28368.1 - 0.046 11.3 11.6 0.14 9.6 5.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Sulfatase_C PF14707.6 CAR28368.1 - 0.07 13.9 1.8 12 6.6 0.1 2.6 2 1 1 3 3 3 0 C-terminal region of aryl-sulfatase Fib_alpha PF08702.10 CAR28368.1 - 0.12 12.5 11.3 0.12 12.5 3.1 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF501 PF04417.12 CAR28368.1 - 0.18 11.6 0.6 0.44 10.4 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF501) FlaC_arch PF05377.11 CAR28368.1 - 0.25 11.8 4.3 2.4 8.6 0.2 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 CAR28368.1 - 0.41 10.7 3.6 2.6 8.1 3.6 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-ATPase_G PF03179.15 CAR28368.1 - 0.49 11.0 6.2 0.19 12.3 3.2 1.9 2 1 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit GreA_GreB_N PF03449.15 CAR28368.1 - 2.4 8.4 7.7 0.75 10.0 4.0 2.1 2 1 0 2 2 2 0 Transcription elongation factor, N-terminal Phage_lysis PF03245.13 CAR28368.1 - 2.9 8.1 8.1 1.7 8.8 4.2 2.2 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein DUF1664 PF07889.12 CAR28368.1 - 6.9 6.7 9.1 7.3 6.7 5.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YlqD PF11068.8 CAR28368.1 - 9.1 6.7 11.8 3.6 8.0 4.4 2.3 1 1 1 2 2 2 0 YlqD protein PMM PF03332.13 CAR28369.1 - 3.5e-113 376.8 0.7 4e-113 376.6 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CAR28369.1 - 3.5e-05 23.7 0.0 0.0011 18.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CAR28369.1 - 0.014 15.0 0.0 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 CAR28369.1 - 0.066 13.5 0.0 0.47 10.7 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF2608 PF11019.8 CAR28369.1 - 0.1 12.0 0.1 0.36 10.3 0.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2608) Ribosomal_L16 PF00252.18 CAR28370.1 - 1.1e-40 138.7 0.1 1.3e-40 138.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-C2H2_jaz PF12171.8 CAR28371.1 - 5.9e-10 39.2 3.7 5.9e-10 39.2 3.7 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CAR28371.1 - 0.00048 20.4 1.6 0.00058 20.2 0.8 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-AD PF07776.15 CAR28371.1 - 0.002 18.3 0.1 0.0044 17.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger associated domain (zf-AD) zf-met PF12874.7 CAR28371.1 - 0.064 13.7 3.9 0.12 12.8 3.9 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 CAR28371.1 - 0.15 11.7 1.5 0.34 10.6 1.5 1.5 1 0 0 1 1 1 0 MYST family zinc finger domain zf-C2HE PF16278.5 CAR28371.1 - 2.4 8.7 5.4 2.2 8.8 1.4 2.7 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger OTU PF02338.19 CAR28372.1 - 9.3e-06 26.2 0.0 1.4e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease VASt PF16016.5 CAR28373.1 - 7.3e-34 117.4 0.2 1.6e-33 116.3 0.2 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CAR28373.1 - 1.2e-28 99.2 0.2 4.1e-28 97.6 0.1 2.0 2 0 0 2 2 2 1 GRAM domain Med14 PF08638.11 CAR28374.1 - 8.4e-53 178.6 2.7 9.6e-53 178.4 0.3 2.1 2 0 0 2 2 2 1 Mediator complex subunit MED14 DNA_primase_lrg PF04104.14 CAR28374.1 - 0.002 17.6 0.2 0.0051 16.3 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CDT1 PF08839.11 CAR28374.1 - 0.063 13.6 0.5 0.14 12.4 0.5 1.5 1 0 0 1 1 1 0 DNA replication factor CDT1 like ADH_N PF08240.12 CAR28375.1 - 8.7e-29 99.6 0.0 1.8e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR28375.1 - 3.9e-27 94.8 0.2 6e-27 94.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR28375.1 - 1.9e-07 32.2 0.0 3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CAR28375.1 - 1.1e-06 28.3 0.1 2.8e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CAR28375.1 - 3.6e-05 23.2 0.3 5.9e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 CAR28375.1 - 0.025 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cu-oxidase_2 PF07731.14 CAR28376.1 - 1.5e-43 147.8 10.4 3.5e-39 133.7 1.3 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CAR28376.1 - 5e-38 129.8 5.8 1e-34 119.1 0.9 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 CAR28376.1 - 1.1e-34 119.9 4.6 1.9e-31 109.4 0.1 3.5 3 1 0 3 3 3 2 Multicopper oxidase Fibritin_C PF07921.12 CAR28376.1 - 0.12 12.5 0.0 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Fibritin C-terminal region GTP_EFTU PF00009.27 CAR28377.1 - 1.2e-62 210.9 0.1 2.1e-62 210.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CAR28377.1 - 1.4e-35 121.7 0.0 2.9e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 CAR28377.1 - 3.5e-30 103.9 0.0 7.1e-30 102.9 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CAR28377.1 - 3e-25 88.1 0.0 5.9e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CAR28377.1 - 6.9e-13 48.8 0.3 2.1e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CAR28377.1 - 9.8e-07 28.7 0.0 2.5e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 CAR28377.1 - 3.2e-05 24.3 0.0 0.0013 19.2 0.1 2.6 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 CAR28377.1 - 0.0055 16.8 0.1 0.015 15.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase rRNA_processing PF08524.11 CAR28378.1 - 1.1e-40 139.1 37.3 1.2e-40 138.9 37.3 1.0 1 0 0 1 1 1 1 rRNA processing DinB PF05163.12 CAR28378.1 - 0.024 14.6 1.7 0.028 14.3 1.7 1.1 1 0 0 1 1 1 0 DinB family AP1AR PF15745.5 CAR28378.1 - 0.1 12.2 14.6 0.12 12.0 14.2 1.3 1 1 0 1 1 1 0 AP-1 complex-associated regulatory protein IpaC_SipC PF09599.10 CAR28378.1 - 0.3 10.5 8.2 0.39 10.2 8.2 1.1 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) SH3_1 PF00018.28 CAR28379.1 - 9e-09 34.8 0.2 2.5e-08 33.4 0.2 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR28379.1 - 2.8e-06 27.1 0.2 8.4e-06 25.6 0.2 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR28379.1 - 5.7e-05 22.7 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Histone_HNS PF00816.21 CAR28379.1 - 0.34 11.8 6.2 5.7 7.8 2.8 2.7 2 0 0 2 2 2 0 H-NS histone family R3H-assoc PF13902.6 CAR28379.1 - 0.53 10.7 7.3 0.25 11.7 4.1 2.1 2 0 0 2 2 2 0 R3H-associated N-terminal domain PPR PF01535.20 CAR28380.1 - 8.1e-09 35.1 7.7 0.0009 19.3 0.1 6.9 8 0 0 8 8 8 2 PPR repeat PPR_long PF17177.4 CAR28380.1 - 1.7e-08 34.1 0.3 1.3e-05 24.7 0.0 2.9 2 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 CAR28380.1 - 6.9e-08 32.6 10.8 0.0032 17.6 0.1 7.4 4 2 5 9 9 9 2 PPR repeat family PPR_1 PF12854.7 CAR28380.1 - 0.0013 18.4 0.0 0.059 13.1 0.0 2.9 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.6 CAR28380.1 - 0.0045 17.0 0.6 10 6.3 0.0 3.9 3 1 0 3 3 3 1 Pentatricopeptide repeat domain TPR_14 PF13428.6 CAR28380.1 - 0.032 15.0 1.0 27 5.9 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ATP13 PF12921.7 CAR28380.1 - 1.5 8.7 5.9 4.4 7.2 0.0 4.2 5 1 0 5 5 5 0 Mitochondrial ATPase expression SPC22 PF04573.12 CAR28381.1 - 1.4e-56 190.7 0.3 1.5e-56 190.5 0.3 1.0 1 0 0 1 1 1 1 Signal peptidase subunit ArAE_1 PF06081.11 CAR28381.1 - 0.085 13.0 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Aromatic acid exporter family member 1 Sugar_tr PF00083.24 CAR28382.1 - 1.1e-56 192.6 17.7 1.5e-56 192.2 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR28382.1 - 1.1e-17 64.0 13.5 1.1e-17 64.0 13.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2644 PF10841.8 CAR28382.1 - 0.42 10.9 7.5 15 5.9 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2644) Flo11 PF10182.9 CAR28383.1 - 1.2e-56 191.0 1.9 3.3e-27 95.5 0.1 2.2 2 0 0 2 2 2 2 Flo11 domain Pfk_N PF18468.1 CAR28383.1 - 0.0051 17.2 0.0 6.4 7.3 0.0 2.5 2 0 0 2 2 2 2 Phosphofructokinase N-terminal domain yeast Flo11 PF10182.9 CAR28384.1 - 9.5e-21 74.5 0.0 1.7e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Flo11 domain Actin PF00022.19 CAR28385.1 - 4e-150 500.0 0.0 1.2e-149 498.4 0.0 1.6 1 1 0 1 1 1 1 Actin TMEM208_SND2 PF05620.11 CAR28386.1 - 5.5e-49 166.2 0.0 6.1e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Ras PF00071.22 CAR28387.1 - 2.1e-64 216.0 0.6 2.5e-64 215.8 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR28387.1 - 7.3e-36 123.0 0.2 1.1e-35 122.4 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR28387.1 - 6.4e-17 61.6 0.2 8e-17 61.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR28387.1 - 1.3e-05 24.7 0.2 1.8e-05 24.2 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR28387.1 - 2.1e-05 24.1 0.3 5.5e-05 22.8 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAR28387.1 - 0.00022 21.3 0.1 0.00033 20.7 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CAR28387.1 - 0.002 17.6 0.1 0.003 17.0 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CAR28387.1 - 0.0043 17.0 0.9 0.11 12.4 0.1 2.2 1 1 1 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 CAR28387.1 - 0.023 14.5 0.1 0.081 12.7 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 CAR28387.1 - 0.068 12.7 0.2 0.35 10.4 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_5 PF07728.14 CAR28387.1 - 0.071 13.1 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CAR28387.1 - 0.084 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CAR28387.1 - 0.087 13.2 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain UPF0121 PF03661.13 CAR28388.1 - 5.2e-14 52.2 19.6 1.1e-13 51.2 19.6 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) Tubulin PF00091.25 CAR28389.1 - 3.3e-67 226.5 0.1 5.5e-67 225.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAR28389.1 - 4.7e-42 143.1 0.0 1e-41 142.0 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 CAR28389.1 - 0.0076 15.5 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin like Misat_Tub_SegII PF10644.9 CAR28389.1 - 0.019 15.3 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CAR28389.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain RNA_pol PF00940.19 CAR28390.1 - 2.5e-181 603.0 0.8 3e-181 602.8 0.1 1.5 2 0 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CAR28390.1 - 3.5e-105 352.1 1.7 5.6e-105 351.5 1.7 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Mob1_phocein PF03637.17 CAR28391.1 - 3.4e-63 212.7 2.0 4.3e-63 212.3 2.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family Methyltransf_34 PF11312.8 CAR28392.1 - 2.5e-92 309.4 0.0 3.1e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Ribosomal_L22e PF01776.17 CAR28393.1 - 8.4e-40 135.5 0.3 1e-39 135.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF726 PF05277.12 CAR28394.1 - 7.3e-135 449.3 1.4 1e-134 448.9 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) AbiJ_NTD5 PF18865.1 CAR28394.1 - 0.03 14.1 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 DUF1456 PF07308.13 CAR28394.1 - 0.057 13.8 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) tRNA_synthFbeta PF17759.1 CAR28395.1 - 5.8e-38 130.5 0.0 8.3e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CAR28395.1 - 8.4e-30 102.8 0.8 4.1e-29 100.6 0.2 2.3 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CAR28395.1 - 1.3e-24 86.8 0.0 2.4e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CAR28395.1 - 1.2e-18 67.1 0.0 5.7e-16 58.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Pkinase PF00069.25 CAR28396.1 - 3.3e-60 203.7 0.0 5.9e-37 127.5 0.1 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28396.1 - 2.2e-25 89.5 0.1 1.1e-19 70.7 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CAR28396.1 - 2.8e-05 23.6 0.9 0.011 15.1 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 CAR28396.1 - 0.00014 21.3 0.0 0.0003 20.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Response_reg PF00072.24 CAR28396.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain APH PF01636.23 CAR28396.1 - 0.0085 16.0 0.4 1.2 9.0 0.2 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Glyco_hydro_30 PF02055.16 CAR28396.1 - 0.049 12.6 0.3 0.33 9.9 0.0 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 TIM-barrel domain FTA2 PF13095.6 CAR28396.1 - 0.05 13.2 0.2 1.3 8.6 0.0 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 CAR28396.1 - 0.093 11.8 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 RNase_T PF00929.24 CAR28397.1 - 5.8e-30 105.0 0.0 7.1e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease RB_A PF01858.17 CAR28397.1 - 0.092 12.6 0.1 0.23 11.3 0.0 1.6 2 1 0 2 2 2 0 Retinoblastoma-associated protein A domain DUF4148 PF13663.6 CAR28397.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) 2OG-FeII_Oxy PF03171.20 CAR28398.1 - 3.8e-15 56.2 0.0 6.8e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CAR28398.1 - 5.3e-15 56.2 0.0 7.8e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal bZIP_1 PF00170.21 CAR28399.1 - 1.3e-05 25.2 7.4 2.5e-05 24.3 7.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CAR28399.1 - 0.00036 20.6 8.7 0.00036 20.6 8.7 1.8 1 1 1 2 2 2 1 Basic region leucine zipper CDC37_N PF03234.14 CAR28399.1 - 0.0042 18.0 2.0 0.0042 18.0 2.0 1.7 1 1 1 2 2 2 1 Cdc37 N terminal kinase binding BUD22 PF09073.10 CAR28399.1 - 0.0045 16.4 6.9 0.0063 15.9 6.9 1.2 1 0 0 1 1 1 1 BUD22 CCDC53 PF10152.9 CAR28399.1 - 0.061 13.7 1.8 0.066 13.6 0.6 1.6 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Aminotran_5 PF00266.19 CAR28400.1 - 2.7e-27 95.7 0.0 3.4e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 CAR28400.1 - 0.016 15.3 0.1 0.06 13.4 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain Aminotran_1_2 PF00155.21 CAR28400.1 - 0.052 12.7 0.0 0.08 12.1 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II SHMT PF00464.19 CAR28401.1 - 1.3e-205 682.6 0.0 1.5e-205 682.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 CAR28401.1 - 5.4e-06 25.8 0.0 1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CAR28401.1 - 0.00045 19.6 0.0 0.0007 19.0 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase FR47 PF08445.10 CAR28401.1 - 0.063 13.3 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 FR47-like protein Catalase-rel PF06628.12 CAR28401.1 - 0.16 12.2 0.0 0.52 10.6 0.0 1.8 2 0 0 2 2 2 0 Catalase-related immune-responsive Glyco_hydro_47 PF01532.20 CAR28402.1 - 3.4e-84 283.4 0.2 4.5e-84 283.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 CAR28402.1 - 0.14 11.7 0.1 2.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 Pkinase PF00069.25 CAR28403.1 - 1.3e-25 90.3 0.0 6.8e-25 87.9 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28403.1 - 4.9e-15 55.5 0.0 7e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR28403.1 - 0.002 18.1 0.0 0.065 13.1 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CAR28403.1 - 0.077 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FA_hydroxylase PF04116.13 CAR28404.1 - 2.1e-21 76.6 15.0 2.1e-21 76.6 15.0 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily malic PF00390.19 CAR28404.1 - 0.0061 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain ABC_tran PF00005.27 CAR28405.1 - 4e-17 63.0 0.0 1.9e-16 60.8 0.0 2.0 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CAR28405.1 - 8.4e-14 52.1 0.1 4.3e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR28405.1 - 1.8e-05 24.3 0.1 0.1 12.0 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAR28405.1 - 0.00097 18.8 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CAR28405.1 - 0.012 16.1 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CAR28405.1 - 0.022 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 CAR28405.1 - 0.024 14.4 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.18 CAR28405.1 - 0.034 13.9 0.2 2.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 CAR28405.1 - 0.056 13.2 0.2 0.16 11.7 0.2 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CAR28405.1 - 0.06 12.7 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 CAR28405.1 - 0.069 13.2 0.3 0.1 12.6 0.3 1.3 1 0 0 1 1 1 0 Dynamin family Zeta_toxin PF06414.12 CAR28405.1 - 0.083 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.23 CAR28405.1 - 0.085 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 CAR28405.1 - 0.1 13.1 0.5 0.35 11.4 0.5 2.0 1 1 0 1 1 1 0 AAA domain AAA_27 PF13514.6 CAR28405.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CAR28405.1 - 0.13 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CAR28405.1 - 0.14 11.7 0.0 0.41 10.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CAR28405.1 - 0.17 12.0 0.1 0.39 10.9 0.1 1.6 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 CAR28406.1 - 1.2e-06 29.1 5.5 5.5 8.0 0.0 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_3 PF13570.6 CAR28406.1 - 0.02 15.4 0.0 65 4.2 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain RabGAP-TBC PF00566.18 CAR28407.1 - 1.6e-15 57.3 9.1 1.6e-15 57.3 9.1 2.7 2 1 0 2 2 2 1 Rab-GTPase-TBC domain STE2 PF02116.15 CAR28408.1 - 7.7e-89 297.7 25.8 9.2e-89 297.4 25.8 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PGAP1 PF07819.13 CAR28409.1 - 3.7e-95 318.1 0.0 5.5e-95 317.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 CAR28409.1 - 0.00013 21.7 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR28409.1 - 0.0012 19.5 0.0 0.0018 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CAR28409.1 - 0.0036 17.1 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 CAR28409.1 - 0.0049 16.7 0.0 0.0078 16.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 CAR28409.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 CAR28409.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase EPL1 PF10513.9 CAR28410.1 - 5.4e-25 88.6 5.6 5.4e-25 88.6 5.6 4.3 3 1 0 3 3 3 2 Enhancer of polycomb-like DUF3835 PF12927.7 CAR28411.1 - 3.6e-17 63.0 0.5 3.6e-17 63.0 0.5 7.6 8 1 0 8 8 8 2 Domain of unknown function (DUF3835) Prefoldin PF02996.17 CAR28411.1 - 1.3e-05 25.1 0.4 1.3e-05 25.1 0.4 3.3 3 1 0 3 3 3 1 Prefoldin subunit GCR1_C PF12550.8 CAR28412.1 - 5.6e-10 39.4 0.6 2.1e-08 34.4 0.6 2.6 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes ApbA_C PF08546.11 CAR28413.1 - 0.12 12.6 0.1 0.39 10.9 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal DUF4993 PF16384.5 CAR28414.1 - 0.069 12.1 0.0 0.086 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function tRNA-synt_2d PF01409.20 CAR28415.1 - 1.1e-87 293.7 0.0 1.3e-87 293.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 CAR28415.1 - 3.1e-13 49.8 3.6 6.2e-13 48.8 0.5 2.8 3 0 0 3 3 3 1 PheRS DNA binding domain 3 PheRS_DBD2 PF18554.1 CAR28415.1 - 4.1e-07 29.9 0.6 1.5e-06 28.1 0.6 2.0 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA_synthFbeta PF17759.1 CAR28415.1 - 4.5e-07 29.5 0.0 0.00018 21.0 0.0 2.3 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 CAR28415.1 - 1.6e-05 24.1 0.0 0.00017 20.8 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 CAR28415.1 - 3.6e-05 23.8 0.0 7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.6 CAR28415.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Histidyl-tRNA synthetase HBB PF06777.11 CAR28416.1 - 0.021 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Helical and beta-bridge domain Pneumo_att_G PF05539.11 CAR28416.1 - 0.086 12.4 1.2 0.13 11.8 1.2 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Fcf2 PF08698.11 CAR28417.1 - 2.1e-29 101.8 0.1 4.6e-29 100.7 0.1 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing GATA PF00320.27 CAR28418.1 - 1e-16 60.2 2.8 2e-16 59.3 2.8 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 CAR28418.1 - 3e-09 36.5 0.7 5.9e-09 35.6 0.7 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pyr_redox_2 PF07992.14 CAR28419.1 - 8.6e-68 228.7 4.9 8.6e-68 228.7 4.9 1.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CAR28419.1 - 1.6e-42 144.2 0.0 5.2e-42 142.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CAR28419.1 - 1.3e-21 76.9 7.4 8e-19 68.0 0.7 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAR28419.1 - 3.7e-13 49.6 6.1 3.2e-11 43.2 0.2 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CAR28419.1 - 8.2e-11 41.7 5.4 9e-10 38.3 5.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAR28419.1 - 4.6e-10 39.6 3.3 0.00022 21.4 1.2 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CAR28419.1 - 5.7e-08 32.2 7.4 6.5e-07 28.8 6.6 2.5 1 1 1 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CAR28419.1 - 5.1e-07 29.1 11.2 9.4e-07 28.2 2.9 2.8 2 1 1 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 CAR28419.1 - 1.1e-05 24.8 4.8 0.012 14.9 0.1 3.0 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CAR28419.1 - 1.2e-05 24.7 8.2 0.0092 15.3 1.0 3.2 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 CAR28419.1 - 1.7e-05 24.6 9.7 0.21 11.1 0.2 4.2 3 1 1 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.14 CAR28419.1 - 3.1e-05 22.8 10.0 0.00078 18.3 1.0 4.0 3 1 1 4 4 4 1 HI0933-like protein K_oxygenase PF13434.6 CAR28419.1 - 0.00068 18.9 0.7 1.6 7.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CAR28419.1 - 0.0059 15.9 0.8 0.0059 15.9 0.8 2.4 1 1 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.18 CAR28419.1 - 0.032 14.1 1.8 0.078 12.9 0.2 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 CAR28419.1 - 0.65 8.8 2.4 0.96 8.2 0.5 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 CAR28419.1 - 1.5 7.8 3.0 6.1 5.8 1.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein LSM PF01423.22 CAR28420.1 - 9.2e-17 60.5 0.1 1e-16 60.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAR28420.1 - 0.037 14.2 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Acetyltransf_1 PF00583.25 CAR28421.1 - 7.5e-16 58.4 0.0 8.7e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CAR28421.1 - 1.3e-11 44.7 0.1 1.8e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CAR28421.1 - 1e-08 35.1 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CAR28421.1 - 0.002 18.2 0.0 0.0038 17.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CAR28421.1 - 0.011 15.8 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF2781 PF10914.8 CAR28423.1 - 1.1e-34 119.9 5.5 1.3e-34 119.8 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF411 PF04214.13 CAR28423.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF DnaJ_C PF01556.18 CAR28424.1 - 5.4e-24 85.0 0.0 8e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAR28424.1 - 1.2e-23 82.9 2.0 2.6e-23 81.9 2.0 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CAR28424.1 - 2e-11 44.1 21.0 3.5e-11 43.3 21.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 CAR28424.1 - 0.0029 17.6 8.0 0.049 13.7 2.0 2.3 1 1 1 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrom_c3_2 PF14537.6 CAR28424.1 - 0.21 12.1 10.3 3.5 8.2 2.0 2.5 1 1 1 2 2 2 0 Cytochrome c3 Anti-TRAP PF15777.5 CAR28424.1 - 2.4 8.2 19.7 0.68 9.9 6.5 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrome_C7 PF14522.6 CAR28424.1 - 7.5 6.6 13.7 7.5 6.6 9.7 2.3 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c Haem_degrading PF03928.14 CAR28425.1 - 2.4e-14 53.4 0.0 2.9e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading Meleagrin PF08189.11 CAR28425.1 - 0.35 10.6 1.6 2.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Meleagrin/Cygnin family HSP9_HSP12 PF04119.12 CAR28426.1 - 8.8e-25 86.9 7.2 8.8e-24 83.7 4.7 2.1 2 0 0 2 2 2 1 Heat shock protein 9/12 Apolipoprotein PF01442.18 CAR28426.1 - 0.048 13.5 2.5 0.089 12.7 2.5 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1771 PF08590.10 CAR28426.1 - 0.054 13.9 5.4 0.078 13.4 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1771) DUF883 PF05957.13 CAR28426.1 - 0.13 12.8 1.5 3.9 8.1 0.5 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 CAR28426.1 - 0.16 12.5 5.6 9.7 6.8 5.6 2.4 1 1 0 1 1 1 0 YtxH-like protein MT0933_antitox PF14013.6 CAR28426.1 - 0.2 12.0 4.3 9.3 6.6 0.0 3.0 2 1 0 2 2 2 0 MT0933-like antitoxin protein Mt_ATP-synt_B PF05405.14 CAR28426.1 - 0.55 9.8 3.0 3 7.4 0.1 2.4 1 1 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) zf-CCHC PF00098.23 CAR28428.1 - 0.16 12.1 0.2 0.34 11.1 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Hamartin PF04388.12 CAR28428.1 - 5.1 5.6 19.7 8.1 5.0 19.7 1.2 1 0 0 1 1 1 0 Hamartin protein WW PF00397.26 CAR28429.1 - 1.3e-09 37.9 2.3 2.1e-09 37.3 2.3 1.4 1 0 0 1 1 1 1 WW domain WD40 PF00400.32 CAR28430.1 - 5.9e-34 115.5 23.3 3.8e-06 27.5 0.1 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat CDC4_D PF16856.5 CAR28430.1 - 1.4e-22 79.3 0.5 2.6e-22 78.4 0.5 1.5 1 0 0 1 1 1 1 Cell division control protein 4 dimerisation domain F-box-like PF12937.7 CAR28430.1 - 4.5e-12 45.7 0.8 1.1e-11 44.4 0.8 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAR28430.1 - 4.2e-09 36.1 0.2 9.8e-09 34.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 CAR28430.1 - 0.0075 16.5 1.1 3.7 7.9 0.0 4.1 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain JmjC PF02373.22 CAR28430.1 - 0.016 15.6 0.0 0.054 13.9 0.0 1.9 1 0 0 1 1 1 0 JmjC domain, hydroxylase Saf_2TM PF18303.1 CAR28431.1 - 0.0046 16.5 1.1 0.0068 16.0 1.1 1.2 1 0 0 1 1 1 1 SAVED-fused 2TM effector domain PIG-P PF08510.12 CAR28431.1 - 0.065 13.2 0.3 0.086 12.8 0.3 1.2 1 0 0 1 1 1 0 PIG-P SMC_N PF02463.19 CAR28432.1 - 9.1e-52 175.7 47.2 4.2e-51 173.5 47.2 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CAR28432.1 - 4.1e-25 88.3 0.0 1.1e-24 87.0 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 CAR28432.1 - 6.6e-08 32.2 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CAR28432.1 - 1.5e-07 31.6 2.9 1.9e-05 24.7 0.0 5.0 4 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system TolA_bind_tri PF16331.5 CAR28432.1 - 0.0065 16.5 0.4 0.0065 16.5 0.4 9.1 8 2 2 10 10 10 2 TolA binding protein trimerisation BLM10_mid PF16507.5 CAR28433.1 - 1.5e-166 555.1 8.4 1.5e-166 555.1 8.4 2.6 3 0 0 3 3 3 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 CAR28433.1 - 1.2e-30 105.6 0.6 6.5e-30 103.3 0.5 2.3 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal DUF3437 PF11919.8 CAR28433.1 - 3.8e-28 97.2 0.7 1.2e-25 89.2 0.0 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) UTP15_C PF09384.10 CAR28433.1 - 0.029 14.1 0.9 0.099 12.3 0.1 2.4 2 0 0 2 2 2 0 UTP15 C terminal HEAT PF02985.22 CAR28433.1 - 0.12 12.7 0.1 2.8 8.4 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat Ras PF00071.22 CAR28434.1 - 1e-63 213.8 0.3 1.3e-63 213.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR28434.1 - 5.6e-37 126.6 0.2 8.8e-37 126.0 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR28434.1 - 9.6e-19 67.5 0.1 1.2e-18 67.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CAR28434.1 - 1.3e-08 34.9 0.7 0.00024 21.0 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CAR28434.1 - 3.7e-07 29.7 0.2 4.7e-07 29.4 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CAR28434.1 - 6.6e-07 28.9 0.1 7.7e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR28434.1 - 3.2e-06 27.2 0.1 5.3e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR28434.1 - 1.4e-05 24.7 0.3 0.00017 21.2 0.1 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CAR28434.1 - 0.0021 17.6 0.1 0.028 14.0 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MCM PF00493.23 CAR28434.1 - 0.0093 15.1 0.1 0.064 12.3 0.0 2.0 2 1 0 2 2 2 1 MCM P-loop domain AAA_7 PF12775.7 CAR28434.1 - 0.02 14.4 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CAR28434.1 - 0.029 14.1 4.8 0.16 11.7 0.8 3.2 2 1 1 3 3 3 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CAR28434.1 - 0.035 14.4 0.1 0.16 12.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CAR28434.1 - 0.065 13.7 0.0 1 9.8 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 CAR28434.1 - 0.071 12.9 0.0 0.35 10.6 0.0 1.9 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CAR28434.1 - 0.1 13.0 0.0 0.14 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 CAR28434.1 - 0.17 11.4 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain VTC PF09359.10 CAR28435.1 - 4.9e-91 304.9 0.1 4.9e-91 304.9 0.1 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 CAR28435.1 - 4.5e-12 46.6 13.3 0.00072 19.6 0.2 4.3 3 1 1 4 4 4 4 SPX domain DUF202 PF02656.15 CAR28435.1 - 6.5e-12 45.7 2.1 6.5e-12 45.7 2.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4149 PF13664.6 CAR28435.1 - 0.03 14.6 1.5 0.054 13.8 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) Peptidase_U4 PF03419.13 CAR28435.1 - 0.17 11.1 2.0 0.29 10.4 2.0 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Presenilin PF01080.17 CAR28435.1 - 1.4 7.6 3.9 3.5 6.3 3.9 1.6 1 0 0 1 1 1 0 Presenilin Peptidase_C48 PF02902.19 CAR28436.1 - 3.2e-38 131.8 7.5 6.8e-38 130.7 0.1 3.0 2 1 1 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain MutS_V PF00488.21 CAR28437.1 - 9.7e-51 172.5 0.0 2.2e-50 171.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAR28437.1 - 6e-27 95.1 2.3 6e-27 95.1 2.3 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 CAR28437.1 - 7.1e-11 42.3 1.5 3.1e-10 40.3 0.0 2.7 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.17 CAR28437.1 - 1.9e-09 37.9 1.0 4e-09 36.9 0.1 2.0 2 0 0 2 2 2 1 MutS domain II AAA_14 PF13173.6 CAR28437.1 - 0.13 12.3 0.9 11 6.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain SIR2 PF02146.17 CAR28438.1 - 1.1e-49 168.7 0.0 1.6e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zf-LYAR PF08790.11 CAR28438.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger NFACT-C PF11923.8 CAR28439.1 - 8.5e-33 112.4 0.6 8.5e-33 112.4 0.6 4.0 2 1 1 3 3 3 1 NFACT protein C-terminal domain FbpA PF05833.11 CAR28439.1 - 2.6e-22 79.2 0.4 2.6e-22 79.2 0.4 3.1 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 CAR28439.1 - 1.1e-17 64.6 0.0 3.3e-17 63.1 0.0 1.9 1 0 0 1 1 1 1 NFACT protein RNA binding domain Serglycin PF04360.12 CAR28439.1 - 0.19 11.7 4.7 0.19 11.7 1.8 2.4 2 0 0 2 2 2 0 Serglycin Clat_adaptor_s PF01217.20 CAR28440.1 - 8e-17 61.5 0.5 3.5e-16 59.4 0.5 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Bromo_TP PF07524.13 CAR28441.1 - 1.1e-05 25.4 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated NUC173 PF08161.12 CAR28442.1 - 1e-71 240.8 0.2 1.8e-69 233.5 0.0 3.8 4 1 0 4 4 4 1 NUC173 domain UME PF08064.13 CAR28442.1 - 0.048 13.6 1.9 0.37 10.7 0.1 3.5 4 0 0 4 4 4 0 UME (NUC010) domain HEAT PF02985.22 CAR28442.1 - 0.079 13.3 0.0 13 6.4 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat SapB_1 PF05184.15 CAR28442.1 - 0.69 10.0 2.0 1.6 8.8 0.4 2.5 2 0 0 2 2 2 0 Saposin-like type B, region 1 Ribosomal_S16 PF00886.19 CAR28443.1 - 9.6e-25 86.4 0.1 1.3e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 DEAD_2 PF06733.15 CAR28445.1 - 5.1e-52 176.0 0.1 8.2e-52 175.4 0.1 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CAR28445.1 - 2.8e-47 161.1 0.0 5.2e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 CAR28445.1 - 3.4e-05 23.9 0.0 0.31 11.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR28445.1 - 9.4e-05 22.3 0.1 0.032 14.0 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR28445.1 - 0.0071 16.6 0.4 2.4 8.4 0.4 2.9 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 CAR28445.1 - 0.035 13.5 0.0 3.1 7.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein zf-TFIIIC PF12660.7 CAR28446.1 - 6.5e-10 38.9 0.0 1.8e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex ANAPC4_WD40 PF12894.7 CAR28446.1 - 0.00012 22.3 0.2 0.044 14.1 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 CAR28446.1 - 0.014 15.3 0.6 6.4 6.7 0.1 3.1 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term NPC1_N PF16414.5 CAR28447.1 - 2.1e-80 269.8 17.2 3.4e-80 269.1 17.2 1.4 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 CAR28447.1 - 1.2e-57 195.7 21.6 4.2e-30 104.5 10.9 3.1 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.8 CAR28447.1 - 2.2e-41 141.2 7.7 2.2e-41 141.2 7.7 2.9 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CAR28447.1 - 3.5e-05 22.9 23.3 0.0011 18.0 9.2 2.2 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.19 CAR28447.1 - 0.0018 16.0 19.2 0.0024 15.6 14.8 2.1 2 0 0 2 2 2 2 AcrB/AcrD/AcrF family PPR_2 PF13041.6 CAR28448.1 - 4.8e-16 58.7 3.8 3.6e-07 30.3 0.6 4.2 4 0 0 4 4 4 3 PPR repeat family PPR_3 PF13812.6 CAR28448.1 - 3.1e-05 24.0 0.9 0.13 12.3 0.1 3.5 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 CAR28448.1 - 0.0001 21.9 0.1 1.2 8.8 0.1 3.7 3 0 0 3 3 3 2 PPR repeat PPR PF01535.20 CAR28448.1 - 7.5 7.0 6.9 1.1e+02 3.4 0.5 4.7 5 0 0 5 5 5 0 PPR repeat Pil1 PF13805.6 CAR28449.1 - 9.3e-121 402.3 0.1 1.1e-120 402.1 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.10 CAR28449.1 - 0.0015 18.7 0.5 0.039 14.2 0.5 2.8 2 0 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit Nop10p PF04135.12 CAR28449.1 - 0.27 11.3 2.0 5.2 7.2 0.1 2.4 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Pribosyltran PF00156.27 CAR28450.1 - 1.3e-15 57.3 0.0 1.7e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1722 PF08349.11 CAR28450.1 - 0.06 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) CdvA PF18822.1 CAR28452.1 - 0.19 11.6 1.4 0.21 11.4 0.1 1.7 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DEAD PF00270.29 CAR28453.1 - 1.2e-39 135.9 0.1 2e-39 135.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR28453.1 - 6.1e-24 84.5 0.0 1.4e-22 80.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CAR28453.1 - 3.4e-17 62.4 0.1 1e-16 60.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CAR28453.1 - 7.6e-06 26.0 2.5 1.3e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CAR28453.1 - 0.0012 18.4 4.5 0.02 14.5 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ERCC3_RAD25_C PF16203.5 CAR28453.1 - 0.0018 17.5 0.3 0.0018 17.5 0.3 3.0 2 2 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase AAA_22 PF13401.6 CAR28453.1 - 0.02 15.2 0.2 0.066 13.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain PseudoU_synth_1 PF01416.20 CAR28454.1 - 3e-35 120.9 0.0 3.3e-31 107.9 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF573 PF04504.14 CAR28454.1 - 0.14 12.8 2.4 0.42 11.3 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF573 EAP30 PF04157.16 CAR28455.1 - 2.9e-56 190.4 0.0 3.2e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family GOLGA2L5 PF15070.6 CAR28455.1 - 0.1 11.2 0.2 0.14 10.8 0.2 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Hat1_N PF10394.9 CAR28456.1 - 8.3e-45 152.9 2.8 1.5e-44 152.0 2.8 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 CAR28456.1 - 4.9e-06 26.8 0.0 1.6e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR28456.1 - 0.0023 17.9 0.0 0.0089 16.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Citrate_synt PF00285.21 CAR28458.1 - 5.2e-92 308.7 0.0 6.3e-92 308.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain MmgE_PrpD PF03972.14 CAR28459.1 - 1.7e-144 481.6 0.0 2.1e-144 481.3 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family PUF PF00806.19 CAR28459.1 - 0.083 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Nic96 PF04097.14 CAR28460.1 - 1.8e-204 680.8 12.8 2.4e-204 680.4 12.8 1.1 1 0 0 1 1 1 1 Nup93/Nic96 PPI_Ypi1 PF07491.11 CAR28461.1 - 1.2e-24 85.9 6.5 4.1e-24 84.2 6.5 1.9 1 0 0 1 1 1 1 Protein phosphatase inhibitor zf-CCCH_3 PF15663.5 CAR28461.1 - 0.034 14.3 1.4 2.3 8.5 0.2 2.3 1 1 1 2 2 2 0 Zinc-finger containing family SR-25 PF10500.9 CAR28461.1 - 0.29 10.7 18.3 0.75 9.4 17.3 1.8 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein JAB PF01398.21 CAR28462.1 - 2.4e-31 108.2 1.7 2.5e-31 108.1 0.2 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CAR28462.1 - 5.5e-10 39.7 1.5 1.3e-09 38.5 1.5 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CAR28462.1 - 2.6e-07 30.4 0.0 4.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-UBP PF02148.19 CAR28463.1 - 5.8e-10 39.4 0.4 1.2e-09 38.3 0.4 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.29 CAR28463.1 - 2.8e-07 30.3 0.4 4.6e-07 29.6 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GHD PF17834.1 CAR28463.1 - 0.97 9.5 4.5 7.7 6.7 0.0 3.4 3 0 0 3 3 3 0 Beta-sandwich domain in beta galactosidase Peptidase_M24 PF00557.24 CAR28464.1 - 3.7e-57 193.4 0.0 4.9e-57 193.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CAR28464.1 - 2.8e-22 78.7 0.0 6.1e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 CAR28464.1 - 0.17 11.9 0.6 0.4 10.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) MFS_1 PF07690.16 CAR28466.1 - 9.7e-32 110.2 39.4 9.7e-32 110.2 39.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CAR28466.1 - 0.00012 20.5 6.0 0.00027 19.4 6.0 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF123 PF01986.16 CAR28467.1 - 0.12 12.9 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF123 Rad21_Rec8_N PF04825.13 CAR28468.1 - 3.1e-15 56.3 0.0 6.5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CAR28468.1 - 0.097 12.0 0.0 0.42 9.9 0.0 2.1 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein ICL PF00463.21 CAR28469.1 - 5.5e-165 549.8 0.0 6.4e-165 549.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CAR28469.1 - 5.4e-07 29.3 0.0 1.3e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase AAA_33 PF13671.6 CAR28471.1 - 5.8e-07 29.8 0.0 0.0069 16.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CAR28471.1 - 9.3e-06 26.2 0.0 5.6e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAR28471.1 - 3.3e-05 24.3 0.0 5.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR28471.1 - 0.0003 21.1 0.0 0.00058 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CAR28471.1 - 0.00059 20.3 0.0 0.033 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CAR28471.1 - 0.00065 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CAR28471.1 - 0.00066 18.9 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain PRK PF00485.18 CAR28471.1 - 0.00068 19.4 0.0 0.35 10.6 0.0 2.5 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 CAR28471.1 - 0.0016 18.8 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.12 CAR28471.1 - 0.0023 17.2 0.0 0.004 16.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Rad17 PF03215.15 CAR28471.1 - 0.003 17.5 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 CAR28471.1 - 0.0061 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA PF00004.29 CAR28471.1 - 0.0067 16.8 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 CAR28471.1 - 0.009 15.9 0.0 0.044 13.7 0.0 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase TIP49 PF06068.13 CAR28471.1 - 0.011 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 CAR28471.1 - 0.013 15.8 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAR28471.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region KTI12 PF08433.10 CAR28471.1 - 0.02 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CPG4 PF15481.6 CAR28471.1 - 0.024 15.2 0.4 0.041 14.5 0.4 1.3 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 Ploopntkinase3 PF18751.1 CAR28471.1 - 0.025 14.5 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Cytidylate_kin PF02224.18 CAR28471.1 - 0.028 14.2 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_25 PF13481.6 CAR28471.1 - 0.031 13.9 0.0 0.078 12.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain ADK PF00406.22 CAR28471.1 - 0.032 14.3 0.0 0.82 9.8 0.0 2.2 2 0 0 2 2 2 0 Adenylate kinase 6PF2K PF01591.18 CAR28471.1 - 0.045 13.0 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Microtub_bd PF16796.5 CAR28471.1 - 0.049 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Microtubule binding AAA_29 PF13555.6 CAR28471.1 - 0.051 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 CAR28471.1 - 0.052 13.3 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CAR28471.1 - 0.056 12.8 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 CAR28471.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 CAR28471.1 - 0.06 13.3 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 CAR28471.1 - 0.064 13.0 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CAR28471.1 - 0.085 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 CAR28471.1 - 0.099 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CAR28471.1 - 0.13 12.3 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 CAR28471.1 - 0.14 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CAR28471.1 - 0.15 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATP_bind_1 PF03029.17 CAR28471.1 - 0.18 11.6 0.0 0.43 10.3 0.0 1.6 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 CAR28471.1 - 0.19 11.5 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CAR28471.1 - 0.19 11.4 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.9 CAR28471.1 - 0.22 10.4 0.0 0.33 9.8 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF3987 PF13148.6 CAR28471.1 - 0.25 10.3 0.0 0.43 9.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) ETF PF01012.21 CAR28472.1 - 1.1e-38 133.0 0.3 1.9e-38 132.2 0.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CAR28472.1 - 2.2e-32 110.9 0.2 5e-32 109.8 0.2 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Sulfate_transp PF00916.20 CAR28473.1 - 6e-92 308.3 18.5 8.3e-92 307.9 18.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CAR28473.1 - 3.5e-24 84.7 0.0 7.2e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CAR28473.1 - 0.00041 20.6 0.0 0.001 19.4 0.0 1.7 1 1 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CAR28473.1 - 0.0008 19.8 6.8 0.0008 19.8 6.8 2.9 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily DUF1072 PF06380.11 CAR28473.1 - 0.12 12.3 9.0 0.24 11.3 2.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Aldo_ket_red PF00248.21 CAR28475.1 - 8.6e-65 218.8 0.0 1.1e-64 218.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Copper-fist PF00649.18 CAR28476.1 - 2.5e-21 74.9 1.0 2.5e-21 74.9 1.0 1.9 1 1 1 2 2 2 1 Copper fist DNA binding domain Ran-binding PF05508.11 CAR28477.1 - 1e-106 356.4 5.3 1e-106 356.4 5.3 1.5 2 0 0 2 2 2 1 RanGTP-binding protein THOC7 PF05615.13 CAR28477.1 - 0.0018 18.5 2.1 0.0018 18.5 2.1 2.3 2 0 0 2 2 2 1 Tho complex subunit 7 Noelin-1 PF12308.8 CAR28477.1 - 0.0063 16.5 2.6 0.025 14.6 0.6 2.6 2 1 1 3 3 3 1 Neurogenesis glycoprotein CENP-B_dimeris PF09026.10 CAR28477.1 - 0.079 13.4 3.6 0.24 11.8 3.6 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SNF2_N PF00176.23 CAR28478.1 - 1.9e-57 194.6 0.0 3.7e-57 193.6 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad54_N PF08658.10 CAR28478.1 - 3.8e-49 167.3 2.9 4.8e-48 163.7 2.2 2.3 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 CAR28478.1 - 1.7e-16 60.5 0.0 4.5e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR28478.1 - 1.1e-07 32.0 0.0 3.3e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CAR28478.1 - 6.8e-06 25.5 0.1 6.7e-05 22.2 0.1 2.5 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Zn_clus PF00172.18 CAR28479.1 - 0.00067 19.7 6.8 0.0011 19.1 1.5 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Yip1 PF04893.17 CAR28480.1 - 0.33 10.6 8.2 0.67 9.6 8.2 1.6 1 1 0 1 1 1 0 Yip1 domain Phos_pyr_kin PF08543.12 CAR28481.1 - 3.8e-05 23.2 0.0 4.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CAR28481.1 - 0.12 11.7 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Vps55 PF04133.14 CAR28482.1 - 5e-41 139.3 5.9 5.7e-41 139.1 5.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 HSP70 PF00012.20 CAR28483.1 - 7.7e-264 876.4 13.1 8.8e-264 876.2 13.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CAR28483.1 - 1.1e-14 54.0 3.9 1e-12 47.6 1.6 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CAR28483.1 - 9.4e-05 22.2 0.0 0.00021 21.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain YlbD_coat PF14071.6 CAR28483.1 - 0.32 11.3 5.6 0.8 10.0 5.6 1.7 1 0 0 1 1 1 0 Putative coat protein DUF948 PF06103.11 CAR28483.1 - 0.84 9.9 3.8 2.6 8.4 1.6 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HXXSHH PF07586.11 CAR28483.1 - 2.3 7.7 6.7 3.7 7.1 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) CDT1 PF08839.11 CAR28484.1 - 9e-06 26.1 3.0 2.4e-05 24.7 1.9 2.2 2 1 0 2 2 2 1 DNA replication factor CDT1 like CDT1_C PF16679.5 CAR28484.1 - 0.00014 22.2 0.3 0.0011 19.4 0.0 2.2 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Hydrolase PF00702.26 CAR28485.1 - 2.2e-17 64.1 0.1 2.9e-10 40.8 0.0 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CAR28485.1 - 1.2e-14 54.3 0.0 2.6e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CAR28485.1 - 0.00053 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CAR28485.1 - 0.0022 17.8 0.4 0.0069 16.2 0.4 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 CAR28485.1 - 0.16 11.4 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase MCM PF00493.23 CAR28486.1 - 1.6e-96 321.7 0.1 2.7e-96 321.0 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR28486.1 - 3.1e-32 111.1 0.0 6.4e-32 110.1 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAR28486.1 - 4.3e-24 84.8 1.5 8e-24 83.9 1.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CAR28486.1 - 7.8e-09 36.1 0.0 3.3e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAR28486.1 - 2.3e-07 30.4 0.0 2.9e-06 26.8 0.0 2.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CAR28486.1 - 0.008 15.9 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 CAR28486.1 - 0.0089 15.9 0.0 0.024 14.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAR28486.1 - 0.013 15.5 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Stm1_N PF09598.10 CAR28486.1 - 0.11 13.3 1.1 0.44 11.4 1.1 2.0 1 0 0 1 1 1 0 Stm1 eIF-5a PF01287.20 CAR28487.1 - 3e-30 104.1 0.1 4.4e-30 103.6 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CAR28487.1 - 0.0028 17.6 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain QSregVF_b PF12843.7 CAR28487.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.6 1 1 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Anp1 PF03452.14 CAR28488.1 - 2.6e-106 354.9 0.0 2.6e-106 354.9 0.0 3.0 2 1 0 2 2 2 1 Anp1 UBA PF00627.31 CAR28489.1 - 4.8e-29 99.8 4.8 1.8e-15 56.4 0.6 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 CAR28489.1 - 4.9e-15 55.0 0.8 8.9e-15 54.2 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 CAR28489.1 - 7.7e-12 44.8 0.5 1.6e-11 43.7 0.5 1.5 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 CAR28489.1 - 2.2e-07 30.6 0.9 4.6e-07 29.6 0.9 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CAR28489.1 - 2.4e-06 27.8 0.6 4.7e-06 26.9 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 CAR28489.1 - 5.4e-05 23.7 0.7 0.00024 21.6 0.0 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAR28489.1 - 0.00051 20.1 0.0 0.00051 20.1 0.0 1.8 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF1421 PF07223.11 CAR28489.1 - 0.021 14.6 0.1 0.043 13.6 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain (DUF1421) DUF3306 PF11748.8 CAR28489.1 - 0.023 15.6 4.4 0.023 15.6 4.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) CUE PF02845.16 CAR28489.1 - 0.043 13.5 1.7 1.5 8.6 0.0 4.1 5 1 0 5 5 5 0 CUE domain UBA_3 PF09288.10 CAR28489.1 - 0.072 12.9 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain TFIIA PF03153.13 CAR28489.1 - 0.26 11.3 20.4 0.34 10.9 20.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Asp-B-Hydro_N PF05279.11 CAR28489.1 - 7.7 6.5 9.4 15 5.6 9.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Epimerase PF01370.21 CAR28490.1 - 4.8e-18 65.5 0.0 8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR28490.1 - 3.1e-15 55.9 0.0 4.5e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CAR28490.1 - 7.8e-12 45.2 0.1 1.9e-11 44.0 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CAR28490.1 - 4.8e-11 42.3 0.2 8.5e-10 38.2 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CAR28490.1 - 2.8e-08 33.9 0.0 7.3e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 CAR28490.1 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 CAR28490.1 - 1.2e-06 27.9 0.0 2.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 CAR28490.1 - 5.7e-06 26.4 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 CAR28490.1 - 0.00049 19.7 0.1 0.0012 18.4 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.6 CAR28490.1 - 0.0097 15.5 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 CAR28490.1 - 0.024 13.7 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 CAR28490.1 - 0.049 14.2 0.0 0.12 13.0 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CAR28490.1 - 0.081 13.0 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HAD_2 PF13419.6 CAR28491.1 - 1.3e-05 25.3 0.1 1.9e-05 24.9 0.1 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR28491.1 - 0.00042 20.3 0.0 0.00078 19.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CAR28491.1 - 0.00096 19.5 0.0 0.0039 17.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SLD3 PF08639.10 CAR28491.1 - 0.15 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 DUF5333 PF17267.2 CAR28491.1 - 0.15 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5333) Cytochrom_C PF00034.21 CAR28492.1 - 3.4e-11 44.1 0.2 5.7e-11 43.4 0.2 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CAR28492.1 - 2.9e-07 30.7 1.8 1.9e-06 28.1 1.8 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CAR28492.1 - 0.083 12.6 1.2 0.37 10.5 0.2 2.1 2 1 0 2 2 2 0 Cytochrome c-550 domain Glyco_hydro_16 PF00722.21 CAR28493.1 - 3.5e-45 153.6 8.4 5.8e-45 152.9 8.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 CAR28493.1 - 0.096 13.2 15.0 0.2 12.1 15.0 1.5 1 0 0 1 1 1 0 Chitin recognition protein YcgR_2 PF12945.7 CAR28493.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein YcgR NAD_kinase PF01513.21 CAR28494.1 - 6.7e-90 301.2 0.0 1e-89 300.6 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CAR28494.1 - 0.0039 16.8 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain GDA1_CD39 PF01150.17 CAR28495.1 - 5.6e-125 417.3 0.0 7.8e-125 416.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CAR28495.1 - 0.019 14.4 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family Isy1 PF06246.12 CAR28496.1 - 6.5e-54 183.2 11.8 4.1e-52 177.3 11.8 2.0 1 1 0 1 1 1 1 Isy1-like splicing family DUF1672 PF07901.11 CAR28496.1 - 0.06 12.7 0.1 0.09 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) YolD PF08863.10 CAR28496.1 - 0.22 11.6 0.3 0.22 11.6 0.3 2.4 2 1 1 3 3 3 0 YolD-like protein DUP PF00674.18 CAR28497.1 - 1.4e-07 31.6 0.1 1.4e-07 31.6 0.1 2.0 2 0 0 2 2 2 1 DUP family DUP PF00674.18 CAR28498.1 - 1.1e-07 32.0 0.4 1.1e-07 32.0 0.4 2.7 2 1 1 3 3 3 1 DUP family MutS_IV PF05190.18 CAR28500.1 - 0.01 16.2 1.5 0.29 11.5 0.0 2.8 2 0 0 2 2 2 0 MutS family domain IV fn3 PF00041.21 CAR28500.1 - 0.034 14.5 0.1 0.2 12.0 0.1 2.4 1 1 0 1 1 1 0 Fibronectin type III domain Prefoldin PF02996.17 CAR28500.1 - 0.05 13.5 6.4 1 9.3 2.4 2.9 2 0 0 2 2 2 0 Prefoldin subunit CD52 PF15116.6 CAR28500.1 - 0.087 12.9 4.1 0.16 12.1 0.5 3.0 3 0 0 3 3 3 0 CAMPATH-1 antigen DUF5339 PF17274.2 CAR28500.1 - 0.089 13.7 1.5 0.23 12.4 1.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5339) DUF5082 PF16888.5 CAR28500.1 - 0.26 11.6 13.1 0.11 12.7 7.7 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) YL1_C PF08265.11 CAR28501.1 - 6.4e-12 45.0 0.2 9.6e-12 44.5 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain RseA_C PF03873.13 CAR28501.1 - 0.0045 17.2 2.4 0.0076 16.5 2.4 1.3 1 0 0 1 1 1 1 Anti sigma-E protein RseA, C-terminal domain Beta_elim_lyase PF01212.21 CAR28502.1 - 6e-76 255.5 0.0 7.6e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase FAD_binding_2 PF00890.24 CAR28503.1 - 3.6e-73 247.0 0.0 4.1e-73 246.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CAR28503.1 - 9.7e-11 41.8 0.1 6.4e-09 35.9 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CAR28503.1 - 1.6e-07 31.5 0.2 7.1e-07 29.4 0.1 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CAR28503.1 - 1.9e-06 27.3 2.5 7.2e-06 25.4 0.9 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CAR28503.1 - 1.7e-05 24.2 0.3 0.00078 18.7 0.0 2.4 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 CAR28503.1 - 2.2e-05 24.0 1.6 5.5e-05 22.7 0.5 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CAR28503.1 - 3.4e-05 23.3 0.8 0.00037 19.9 0.8 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CAR28503.1 - 0.00018 20.7 0.1 0.45 9.5 0.3 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Trigger_C PF05698.14 CAR28503.1 - 0.00022 21.3 2.0 0.00086 19.4 0.2 2.2 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus GIDA PF01134.22 CAR28503.1 - 0.0014 17.8 2.2 0.052 12.6 0.0 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CAR28503.1 - 0.0058 17.2 0.1 7.9 7.1 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CAR28503.1 - 0.019 15.0 0.0 0.69 9.9 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 CAR28503.1 - 0.02 13.8 0.1 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase GMC_oxred_N PF00732.19 CAR28503.1 - 0.054 12.9 1.1 0.87 8.9 0.0 2.4 2 0 0 2 2 2 0 GMC oxidoreductase HI0933_like PF03486.14 CAR28503.1 - 0.056 12.2 8.2 0.063 12.0 0.4 3.1 3 1 0 3 3 3 0 HI0933-like protein Amino_oxidase PF01593.24 CAR28503.1 - 0.082 12.2 0.0 4.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF903 PF06004.12 CAR28503.1 - 0.23 11.4 1.1 0.64 10.0 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF903) Pyr_redox_3 PF13738.6 CAR28503.1 - 0.4 9.9 3.6 0.82 8.9 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Sedlin_N PF04628.13 CAR28504.1 - 1.9e-11 44.2 0.2 2.4e-11 43.9 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DNA_ligase_IV PF11411.8 CAR28504.1 - 0.18 12.0 0.2 0.67 10.1 0.0 2.0 2 0 0 2 2 2 0 DNA ligase IV DUF676 PF05057.14 CAR28505.1 - 1.8e-39 135.5 0.0 2.8e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 CAR28505.1 - 5.9e-05 23.8 0.0 8.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CAR28505.1 - 0.00019 21.2 0.0 0.00077 19.3 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 CAR28505.1 - 0.00057 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 CAR28505.1 - 0.015 15.2 0.0 0.041 13.7 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Metallophos PF00149.28 CAR28507.1 - 9.9e-33 114.4 0.2 1.5e-32 113.8 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STAT_alpha PF01017.20 CAR28507.1 - 0.18 11.7 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain OHCU_decarbox PF09349.10 CAR28508.1 - 4.3e-38 131.2 0.2 5.3e-38 130.9 0.2 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Rho_GDI PF02115.17 CAR28509.1 - 9.6e-62 208.2 1.7 1.1e-61 208.0 1.7 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor MucBP_2 PF17965.1 CAR28509.1 - 0.1 13.2 0.7 13 6.4 0.0 3.1 3 0 0 3 3 3 0 Mucin binding domain R3H PF01424.22 CAR28510.1 - 3.2e-11 43.1 0.2 5.9e-11 42.2 0.2 1.5 1 0 0 1 1 1 1 R3H domain Ufd2P_core PF10408.9 CAR28511.1 - 4.4e-197 656.6 6.6 4.4e-197 656.6 6.6 1.5 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 CAR28511.1 - 1.4e-28 98.9 2.4 1.5e-28 98.7 0.8 2.0 2 0 0 2 2 2 1 U-box domain AsnC_trans_reg PF01037.21 CAR28511.1 - 0.091 12.7 0.0 9 6.3 0.0 2.7 2 0 0 2 2 2 0 Lrp/AsnC ligand binding domain Ribosomal_L29 PF00831.23 CAR28512.1 - 1.3e-16 60.2 4.2 1.3e-16 60.2 4.2 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein PilJ PF13675.6 CAR28512.1 - 0.064 13.3 1.3 0.071 13.1 0.7 1.4 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Arf PF00025.21 CAR28513.1 - 2.5e-78 261.5 0.1 2.9e-78 261.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAR28513.1 - 7.9e-15 55.1 0.1 1.1e-14 54.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAR28513.1 - 1.3e-14 54.0 0.0 1.6e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CAR28513.1 - 1.4e-14 54.0 0.0 1.5e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CAR28513.1 - 2.5e-12 46.7 1.6 1.2e-08 34.6 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CAR28513.1 - 5.5e-10 39.0 0.0 6.9e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR28513.1 - 6.4e-06 26.2 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 CAR28513.1 - 0.0073 16.0 0.2 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 CAR28513.1 - 0.026 15.0 0.1 0.056 14.0 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CAR28513.1 - 0.032 14.4 0.8 0.097 12.8 0.8 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CAR28513.1 - 0.036 14.0 0.1 5.1 7.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 CAR28513.1 - 0.037 13.6 0.1 0.11 12.0 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain 6PF2K PF01591.18 CAR28513.1 - 0.039 13.2 0.2 0.062 12.6 0.2 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 CAR28513.1 - 0.046 13.3 0.1 7.5 6.1 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 CAR28513.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CAR28513.1 - 0.087 13.4 0.1 0.14 12.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR28513.1 - 0.15 11.9 0.6 13 5.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain DUF5099 PF17025.5 CAR28514.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5099) Psb28 PF03912.14 CAR28514.1 - 0.17 12.2 0.2 0.5 10.7 0.1 1.9 2 1 0 2 2 2 0 Psb28 protein Sugar_tr PF00083.24 CAR28515.1 - 4.2e-125 418.1 24.5 5.1e-125 417.9 24.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR28515.1 - 3.6e-18 65.6 30.2 3e-13 49.4 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.13 CAR28515.1 - 0.005 17.5 2.0 0.0067 17.1 0.8 1.8 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec31 PF11549.8 CAR28516.1 - 3.6e-24 84.4 6.0 1.5e-23 82.4 6.0 2.2 1 0 0 1 1 1 1 Protein transport protein SEC31 ANAPC4_WD40 PF12894.7 CAR28516.1 - 6.5e-09 36.0 1.1 0.08 13.3 0.0 3.8 2 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain SRA1 PF07304.11 CAR28516.1 - 7.1e-09 35.6 0.0 7.1e-09 35.6 0.0 3.0 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 CAR28516.1 - 2e-08 34.7 10.2 0.0014 19.4 0.1 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat Sec16_C PF12931.7 CAR28516.1 - 2.5e-06 27.4 0.4 1.2e-05 25.1 0.4 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.15 CAR28516.1 - 2.1e-05 24.6 0.1 7.2e-05 22.9 0.1 1.9 1 1 0 1 1 1 1 Prp18 domain CHCH PF06747.13 CAR28517.1 - 0.019 15.1 6.0 0.041 14.0 6.0 1.6 1 0 0 1 1 1 0 CHCH domain Scm3 PF10384.9 CAR28518.1 - 1.7e-20 72.5 0.9 1.7e-20 72.5 0.9 2.2 2 0 0 2 2 2 1 Centromere protein Scm3 SpvB PF03534.13 CAR28518.1 - 0.011 14.9 3.3 0.016 14.4 3.3 1.2 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein Pro_isomerase PF00160.21 CAR28519.1 - 1.2e-43 149.2 0.1 2e-43 148.4 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 CAR28519.1 - 2.8e-07 30.1 1.6 4.2e-07 29.5 0.1 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAR28519.1 - 6e-05 22.8 2.4 0.00053 19.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR28519.1 - 0.0043 17.2 0.0 0.0043 17.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat SLX9 PF15341.6 CAR28519.1 - 0.035 14.5 1.9 0.082 13.3 1.9 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 TPR_6 PF13174.6 CAR28519.1 - 0.12 13.0 0.8 0.5 11.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SpoIISA_toxin PF14171.6 CAR28519.1 - 6.4 6.4 8.6 18 5.0 0.2 2.1 1 1 1 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system RNA_pol_Rpb1_1 PF04997.12 CAR28521.1 - 7.7e-116 386.8 0.2 1.6e-115 385.8 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CAR28521.1 - 1.5e-106 355.7 0.1 2.6e-106 354.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CAR28521.1 - 9.4e-78 260.2 0.4 2.5e-77 258.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CAR28521.1 - 2.2e-63 213.5 0.4 4.3e-63 212.6 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CAR28521.1 - 1e-46 158.3 3.1 2.7e-46 156.9 3.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CAR28521.1 - 1e-45 155.5 0.0 3.4e-45 153.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CAR28521.1 - 2.5e-34 117.5 0.1 6.7e-34 116.1 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CAR28521.1 - 1.9e-14 53.1 337.8 0.013 15.8 11.1 16.4 8 2 1 16 16 16 14 RNA polymerase Rpb1 C-terminal repeat DUF4123 PF13503.6 CAR28521.1 - 0.026 14.9 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) BPL_N PF09825.9 CAR28522.1 - 3.5e-119 398.3 0.0 4.3e-119 398.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 CAR28522.1 - 3.6e-23 81.9 0.0 6.7e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CAR28522.1 - 2.3e-09 37.0 0.0 5.1e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain CDP-OH_P_transf PF01066.21 CAR28523.1 - 4.3e-15 56.2 0.3 4.3e-15 56.2 0.3 1.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cpn60_TCP1 PF00118.24 CAR28524.1 - 7.2e-147 490.0 10.8 8.1e-147 489.8 10.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family D123 PF07065.14 CAR28525.1 - 5.8e-106 354.1 1.8 7.3e-106 353.8 1.8 1.1 1 0 0 1 1 1 1 D123 R2K_2 PF18299.1 CAR28525.1 - 0.061 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 CAR28525.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 ApbA_C PF08546.11 CAR28526.1 - 2.7e-25 89.0 0.1 4.3e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CAR28526.1 - 3.7e-22 78.6 0.1 6.3e-22 77.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Glyco_hydro_16 PF00722.21 CAR28527.1 - 1.3e-44 151.7 0.0 1.9e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 CAR28527.1 - 0.19 12.2 12.7 0.37 11.3 12.7 1.4 1 0 0 1 1 1 0 Chitin recognition protein Ribonuclease_T2 PF00445.18 CAR28528.1 - 3e-40 138.4 0.3 4.3e-40 137.9 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family EF1G PF00647.19 CAR28528.1 - 0.11 12.5 0.1 1.1 9.4 0.0 2.3 2 1 0 2 2 2 0 Elongation factor 1 gamma, conserved domain Transp_cyt_pur PF02133.15 CAR28529.1 - 1.5e-70 238.2 31.4 1.8e-70 237.9 31.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Spc29 PF17082.5 CAR28530.1 - 7.1e-12 45.7 16.6 5.3e-08 33.0 1.2 3.0 2 1 1 3 3 3 3 Spindle Pole Component 29 DHR10 PF18595.1 CAR28530.1 - 0.21 11.6 6.9 0.26 11.4 2.3 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain SlyX PF04102.12 CAR28530.1 - 0.62 10.7 12.7 0.23 12.1 1.5 3.0 2 1 1 3 3 3 0 SlyX Y_phosphatase PF00102.27 CAR28531.1 - 3.3e-58 197.0 0.4 2.7e-57 194.1 0.4 2.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CAR28531.1 - 0.0016 18.2 0.8 0.042 13.7 0.0 3.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CAR28531.1 - 0.0096 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family IBN_N PF03810.19 CAR28532.1 - 9.6e-16 57.5 0.4 3.3e-15 55.7 0.4 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CAR28532.1 - 0.011 15.7 0.6 0.011 15.7 0.6 3.8 4 0 0 4 4 4 0 Exportin 1-like protein SCRL PF06876.12 CAR28532.1 - 0.083 13.1 0.2 0.21 11.8 0.2 1.6 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein UNC45-central PF11701.8 CAR28532.1 - 0.22 11.5 3.9 0.35 10.8 1.3 2.7 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central NAPRTase PF04095.16 CAR28533.1 - 3.2e-74 249.6 0.0 4.1e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CAR28533.1 - 4.3e-38 130.5 0.1 8.4e-38 129.6 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain WD40 PF00400.32 CAR28534.1 - 0.0007 20.4 6.6 0.21 12.5 0.2 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat DCAF15_WD40 PF14939.6 CAR28534.1 - 0.0024 17.6 0.0 0.097 12.3 0.0 2.5 2 0 0 2 2 2 1 DDB1-and CUL4-substrate receptor 15, WD repeat CdiI_N PF18228.1 CAR28534.1 - 0.58 10.0 3.4 18 5.2 0.1 3.5 3 0 0 3 3 3 0 CdiI N-terminal domain RNA_pol_N PF01194.17 CAR28535.1 - 2.5e-30 104.6 0.5 2.8e-30 104.4 0.5 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CAR28535.1 - 0.047 13.9 0.2 0.062 13.6 0.2 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Dynamin_N PF00350.23 CAR28536.1 - 7.4e-44 149.8 0.1 2.2e-43 148.2 0.1 1.9 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CAR28536.1 - 1.9e-05 24.7 0.0 0.00013 22.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AKAP7_RIRII_bdg PF10470.9 CAR28536.1 - 0.0069 16.4 0.2 0.026 14.6 0.2 2.0 1 0 0 1 1 1 1 PKA-RI-RII subunit binding domain of A-kinase anchor protein Dynamin_M PF01031.20 CAR28536.1 - 0.047 12.9 7.5 0.11 11.7 0.0 3.3 3 0 0 3 3 3 0 Dynamin central region AAA_16 PF13191.6 CAR28536.1 - 0.074 13.4 0.0 0.34 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CAR28536.1 - 0.14 12.4 0.0 0.42 10.8 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Linker_histone PF00538.19 CAR28537.1 - 2.2e-49 165.7 0.7 6.8e-24 84.0 0.0 2.6 2 0 0 2 2 2 2 linker histone H1 and H5 family DMAP1 PF05499.12 CAR28537.1 - 2 8.3 10.6 0.41 10.5 4.2 2.4 2 0 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) TRF PF08558.10 CAR28538.1 - 4.2e-78 262.2 1.2 5.6e-78 261.8 1.2 1.1 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 CAR28538.1 - 8.2e-07 29.1 0.2 1.7e-06 28.1 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR28538.1 - 0.049 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain T2SSF PF00482.23 CAR28538.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F WD40 PF00400.32 CAR28539.1 - 3.6e-24 84.6 23.7 0.00011 22.9 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR28539.1 - 1.7e-07 31.4 0.1 0.43 10.9 0.0 4.2 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR28539.1 - 0.0052 15.8 0.6 7.7 5.4 0.1 3.6 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CAR28539.1 - 0.027 13.8 0.0 1.7 7.9 0.0 2.8 1 1 1 3 3 3 0 WD40-like domain YEATS PF03366.16 CAR28540.1 - 2.1e-19 69.3 0.2 3.6e-19 68.5 0.2 1.4 1 0 0 1 1 1 1 YEATS family YEATS PF03366.16 CAR28541.1 - 3.6e-20 71.7 0.1 5.8e-20 71.1 0.1 1.3 1 0 0 1 1 1 1 YEATS family BET PF17035.5 CAR28541.1 - 2.5e-07 30.7 0.1 4.8e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation RNA_pol_Rpo13 PF12136.8 CAR28542.1 - 1.4 8.9 6.8 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain Macoilin PF09726.9 CAR28542.1 - 8.2 4.8 18.1 9.8 4.6 18.1 1.1 1 0 0 1 1 1 0 Macoilin family YqeY PF09424.10 CAR28543.1 - 2.6e-22 79.5 3.2 3.6e-22 79.0 3.2 1.2 1 0 0 1 1 1 1 Yqey-like protein z-alpha PF02295.17 CAR28543.1 - 0.024 14.7 0.3 0.07 13.2 0.1 1.9 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain Ku_PK_bind PF08785.11 CAR28543.1 - 0.04 14.1 1.3 0.34 11.1 0.1 2.3 1 1 1 2 2 2 0 Ku C terminal domain like DUF2704 PF10866.8 CAR28543.1 - 0.069 13.0 1.0 0.12 12.3 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2704) Pox_A3L PF05288.11 CAR28543.1 - 0.22 11.5 1.7 0.51 10.4 0.7 2.1 2 0 0 2 2 2 0 Poxvirus A3L Protein Na_Ca_ex_C PF16494.5 CAR28543.1 - 1.5 9.3 5.1 0.64 10.5 1.2 2.0 1 1 1 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain GRAB PF10375.9 CAR28544.1 - 1.2e-06 28.2 0.4 2.8e-06 27.0 0.4 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Golgin_A5 PF09787.9 CAR28544.1 - 6.4e-06 25.9 64.9 0.0018 17.8 19.0 3.5 1 1 3 4 4 4 2 Golgin subfamily A member 5 GAS PF13851.6 CAR28544.1 - 5e-05 22.7 67.4 0.022 14.1 29.0 4.0 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 CAR28544.1 - 0.0001 21.3 63.4 0.12 11.2 14.0 3.3 1 1 2 3 3 3 3 Spc7 kinetochore protein Fez1 PF06818.15 CAR28544.1 - 0.00014 22.4 59.9 0.00036 21.1 19.5 3.1 1 1 0 2 2 2 1 Fez1 ATG16 PF08614.11 CAR28544.1 - 0.00039 20.7 64.6 0.1 12.8 26.6 4.3 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 CAR28544.1 - 0.00089 19.3 71.8 0.083 12.9 21.7 4.5 1 1 3 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 CAR28544.1 - 0.001 18.7 50.0 0.001 18.7 50.0 2.5 1 1 1 2 2 2 1 Intermediate filament protein KASH_CCD PF14662.6 CAR28544.1 - 0.0012 18.7 29.2 0.0012 18.7 29.2 3.6 1 1 2 3 3 3 1 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 CAR28544.1 - 0.0015 19.1 24.8 0.0015 19.1 24.8 4.4 1 1 3 4 4 4 1 Apg6 coiled-coil region Lebercilin PF15619.6 CAR28544.1 - 0.0015 18.2 21.0 0.0015 18.2 21.0 3.9 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease ZapB PF06005.12 CAR28544.1 - 0.015 15.7 5.4 0.015 15.7 5.4 6.5 1 1 5 6 6 5 0 Cell division protein ZapB Sec34 PF04136.15 CAR28544.1 - 0.016 15.1 10.3 0.016 15.1 10.3 4.5 1 1 4 5 5 5 0 Sec34-like family Phage_GP20 PF06810.11 CAR28544.1 - 0.02 14.7 54.4 0.076 12.8 12.0 5.5 1 1 4 5 5 5 0 Phage minor structural protein GP20 TMF_TATA_bd PF12325.8 CAR28544.1 - 0.023 14.9 64.8 0.11 12.7 17.9 5.4 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.8 CAR28544.1 - 0.059 10.9 57.2 0.31 8.5 12.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TACC_C PF05010.14 CAR28544.1 - 0.12 12.2 52.4 0.09 12.6 20.4 3.6 1 1 3 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Atg14 PF10186.9 CAR28544.1 - 0.12 11.4 52.8 0.86 8.6 25.6 3.9 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 CAR28544.1 - 0.14 12.2 41.5 0.4 10.7 10.7 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CAR28544.1 - 0.16 11.3 38.2 0.051 12.9 16.7 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF4201 PF13870.6 CAR28544.1 - 0.17 11.6 62.5 0.57 9.9 11.3 4.1 1 1 3 4 4 4 0 Domain of unknown function (DUF4201) EzrA PF06160.12 CAR28544.1 - 0.24 9.5 57.1 0.027 12.7 29.0 2.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA HMMR_N PF15905.5 CAR28544.1 - 0.49 9.8 68.7 0.48 9.8 17.5 3.8 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal TPR_MLP1_2 PF07926.12 CAR28544.1 - 1 9.4 68.5 3.5 7.7 17.2 5.1 1 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein CCDC144C PF14915.6 CAR28544.1 - 1.2 8.2 65.0 8.7 5.4 34.1 2.9 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region HBM PF16591.5 CAR28544.1 - 1.2 8.5 36.0 0.64 9.4 6.1 3.9 1 1 3 4 4 4 0 Helical bimodular sensor domain DUF2353 PF09789.9 CAR28544.1 - 1.5 8.1 52.7 0.064 12.6 11.1 3.2 2 1 2 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) FPP PF05911.11 CAR28544.1 - 1.9 6.6 63.2 1.5 6.9 32.2 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil FUSC PF04632.12 CAR28544.1 - 2.6 6.5 11.5 3 6.3 10.4 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family MAD PF05557.13 CAR28544.1 - 3 6.1 65.4 0.068 11.5 9.5 3.0 1 1 2 3 3 3 0 Mitotic checkpoint protein ADIP PF11559.8 CAR28544.1 - 4.2 7.4 62.8 0.11 12.6 17.1 5.1 1 1 5 6 6 6 0 Afadin- and alpha -actinin-Binding APG17 PF04108.12 CAR28544.1 - 5.4 6.0 45.9 0.63 9.1 27.1 3.0 1 1 1 2 2 2 0 Autophagy protein Apg17 HIP1_clath_bdg PF16515.5 CAR28544.1 - 5.7 7.6 67.3 0.16 12.6 4.7 5.4 1 1 3 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3450 PF11932.8 CAR28544.1 - 6.4 6.0 52.7 0.039 13.3 15.3 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) PI_PP_I PF18363.1 CAR28544.1 - 7.7 6.8 23.1 4.7 7.5 2.5 4.0 1 1 2 3 3 3 0 Phosphoinositide phosphatase insertion domain IFT57 PF10498.9 CAR28544.1 - 8 5.3 57.0 0.16 10.9 18.6 3.4 1 1 3 4 4 4 0 Intra-flagellar transport protein 57 Rootletin PF15035.6 CAR28544.1 - 8.5 6.3 56.7 0.22 11.5 18.0 3.6 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion RFC1 PF08519.12 CAR28545.1 - 6.1e-60 201.9 0.6 2.8e-59 199.8 0.1 2.2 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CAR28545.1 - 2.3e-13 50.7 0.1 1.8e-12 47.8 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 CAR28545.1 - 1.2e-11 44.8 0.0 4.4e-11 43.0 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RuvB_N PF05496.12 CAR28545.1 - 2.1e-05 24.4 0.0 4.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 CAR28545.1 - 2.3e-05 24.4 0.0 8.4e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 CAR28545.1 - 0.0004 20.8 0.4 0.0023 18.4 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAR28545.1 - 0.00075 19.8 0.0 0.0033 17.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CAR28545.1 - 0.00083 19.8 2.0 0.016 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CAR28545.1 - 0.00084 19.6 0.0 0.0031 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_33 PF13671.6 CAR28545.1 - 0.00086 19.5 0.1 0.0033 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR28545.1 - 0.0032 18.0 0.4 0.013 16.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 CAR28545.1 - 0.0088 16.4 0.0 0.031 14.7 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 CAR28545.1 - 0.011 15.5 0.1 0.05 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CAR28545.1 - 0.018 15.0 0.0 0.082 12.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.14 CAR28545.1 - 0.033 14.2 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 CAR28545.1 - 0.063 13.2 0.1 0.34 10.8 0.0 2.2 1 1 0 2 2 2 0 NTPase AAA_28 PF13521.6 CAR28545.1 - 0.12 12.6 0.9 0.45 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DPPIV_N PF00930.21 CAR28546.1 - 3e-90 302.5 0.1 4.1e-90 302.1 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CAR28546.1 - 1.5e-49 168.4 1.8 2.2e-49 167.8 1.8 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CAR28546.1 - 9.6e-06 26.4 0.0 0.0078 16.8 0.0 2.8 2 1 1 3 3 3 2 Alpha/beta hydrolase family Esterase PF00756.20 CAR28546.1 - 0.00018 21.2 0.1 0.00033 20.4 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 CAR28546.1 - 0.0013 18.1 0.2 1.4 8.1 0.2 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CAR28546.1 - 0.017 14.9 0.3 0.98 9.2 0.3 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.13 CAR28546.1 - 0.048 12.2 0.1 0.098 11.1 0.1 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Ribosomal_L5e PF17144.4 CAR28547.1 - 8.7e-82 273.0 0.9 8.9e-82 272.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CAR28547.1 - 6.4e-32 110.4 6.6 6.4e-32 110.4 6.6 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 CAR28547.1 - 0.0038 17.6 0.5 0.0075 16.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thr_synth_N PF14821.6 CAR28547.1 - 0.01 16.0 0.6 0.68 10.2 0.0 2.8 3 0 0 3 3 3 0 Threonine synthase N terminus GCR1_C PF12550.8 CAR28547.1 - 0.096 13.0 3.9 3.6 8.0 0.2 2.5 2 0 0 2 2 2 0 Transcriptional activator of glycolytic enzymes Colicin_immun PF09204.10 CAR28547.1 - 0.26 11.9 4.1 0.5 10.9 1.8 2.5 2 1 0 2 2 2 0 Bacterial self-protective colicin-like immunity Com_YlbF PF06133.11 CAR28547.1 - 1.2 9.8 8.6 0.58 10.8 6.2 1.7 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA SPT6_acidic PF14632.6 CAR28547.1 - 7.5 7.2 11.1 30 5.3 11.1 2.0 1 1 0 1 1 1 0 Acidic N-terminal SPT6 CtaG_Cox11 PF04442.14 CAR28549.1 - 2.8e-61 205.9 0.1 4.5e-61 205.3 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Zn_clus PF00172.18 CAR28550.1 - 1.6e-05 24.9 7.6 3.7e-05 23.8 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl_transf_1 PF00698.21 CAR28551.1 - 0.0038 16.8 0.0 0.012 15.2 0.0 1.8 1 1 0 1 1 1 1 Acyl transferase domain Mito_carr PF00153.27 CAR28552.1 - 9.6e-66 217.8 0.2 1.9e-25 88.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CAR28552.1 - 0.021 15.2 0.5 0.079 13.3 0.5 2.1 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Serine_protease PF18405.1 CAR28552.1 - 0.11 11.6 0.7 2.4 7.3 0.0 3.1 1 1 1 4 4 4 0 Gammaproteobacterial serine protease DUF2407_C PF13373.6 CAR28553.1 - 1.6e-42 145.0 0.4 2.7e-42 144.2 0.4 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 CAR28553.1 - 7.7e-25 87.5 0.4 1.2e-24 86.9 0.4 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain RNA_pol_Rpb8 PF03870.15 CAR28554.1 - 1.8e-43 148.1 0.0 2e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CAR28554.1 - 0.00055 20.0 0.0 0.9 9.6 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G NifU_N PF01592.16 CAR28555.1 - 2.2e-54 183.1 0.0 2.8e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Roughex PF06020.11 CAR28556.1 - 0.22 10.6 2.5 0.53 9.3 2.5 1.5 1 0 0 1 1 1 0 Drosophila roughex protein DUF1691 PF07950.11 CAR28557.1 - 1.3e-29 103.0 1.0 1.7e-15 57.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 CAR28557.1 - 2.7e-08 33.9 0.8 4e-06 26.9 0.2 2.2 2 0 0 2 2 2 2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PHD PF00628.29 CAR28558.1 - 9.1e-11 41.5 6.1 9.1e-11 41.5 6.1 2.0 2 0 0 2 2 2 1 PHD-finger IL17 PF06083.11 CAR28558.1 - 0.079 13.4 1.8 0.63 10.6 0.1 2.4 2 0 0 2 2 2 0 Interleukin-17 WD40 PF00400.32 CAR28559.1 - 1.6e-05 25.6 5.8 1.4 10.0 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Pkinase PF00069.25 CAR28560.1 - 2.6e-70 236.8 0.0 4e-70 236.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28560.1 - 9.5e-37 126.7 0.0 2.1e-36 125.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR28560.1 - 5.1e-07 29.3 0.0 1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CAR28560.1 - 0.00013 21.7 0.1 0.23 11.1 0.1 2.5 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CAR28560.1 - 0.00072 18.4 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAR28560.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CAR28560.1 - 0.034 13.1 0.2 0.097 11.6 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 CAR28560.1 - 0.056 13.3 0.0 0.25 11.2 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CAR28560.1 - 0.15 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 GrpE PF01025.19 CAR28561.1 - 1.8e-46 157.8 10.3 2.4e-46 157.5 10.3 1.2 1 0 0 1 1 1 1 GrpE PEARLI-4 PF05278.12 CAR28561.1 - 0.019 14.6 5.4 0.029 14.0 5.4 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF812 PF05667.11 CAR28561.1 - 0.02 13.8 9.0 0.025 13.5 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2235 PF09994.9 CAR28561.1 - 0.045 13.1 1.9 0.064 12.6 1.7 1.3 1 1 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Atg14 PF10186.9 CAR28561.1 - 0.16 11.0 4.9 0.2 10.7 4.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LIAS_N PF16881.5 CAR28561.1 - 0.58 10.6 4.2 0.95 9.9 3.4 1.7 1 1 1 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family V_ATPase_I PF01496.19 CAR28561.1 - 0.78 7.6 5.1 0.84 7.5 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vps5 PF09325.10 CAR28561.1 - 1.1 8.8 13.6 1.3 8.5 13.0 1.4 1 1 0 1 1 1 0 Vps5 C terminal like HIP1_clath_bdg PF16515.5 CAR28561.1 - 2.4 8.8 14.8 4.6 7.9 10.4 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 CAR28561.1 - 4.4 7.6 19.9 4.8 7.5 19.2 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.25 CAR28562.1 - 1.2e-65 221.5 0.0 1.8e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28562.1 - 2.1e-41 141.9 0.0 3.3e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR28562.1 - 2.2e-08 33.8 0.0 3.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CAR28562.1 - 0.0027 17.6 1.2 0.0043 17.0 0.1 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CAR28562.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CAR28562.1 - 0.055 13.1 0.3 0.12 12.0 0.3 1.5 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 CAR28562.1 - 7.1 5.5 7.3 0.23 10.4 0.1 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Ribosomal_L35Ae PF01247.18 CAR28563.1 - 4.3e-40 135.8 0.7 4.8e-40 135.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CAR28563.1 - 0.0031 17.7 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain POC3_POC4 PF10448.9 CAR28564.1 - 5.9e-13 49.1 0.3 1.9e-12 47.4 0.3 1.8 1 1 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 PAC4 PF16093.5 CAR28564.1 - 0.00073 19.7 0.1 0.0013 18.8 0.1 1.6 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 DHFR_1 PF00186.19 CAR28565.1 - 3.7e-30 104.8 0.0 5.1e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase Oxysterol_BP PF01237.18 CAR28566.1 - 3e-62 210.6 3.8 6.2e-60 203.0 3.8 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Nop53 PF07767.11 CAR28567.1 - 5e-96 322.5 52.8 5.8e-96 322.3 52.8 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) ABC_membrane_2 PF06472.15 CAR28569.1 - 2.5e-80 269.8 4.4 3.8e-80 269.2 4.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CAR28569.1 - 3.1e-13 50.4 0.0 9.8e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CAR28569.1 - 0.0021 17.6 0.6 0.53 9.7 0.0 2.5 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF1749 PF08538.10 CAR28570.1 - 3.4e-90 302.1 0.0 3.9e-90 302.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 CAR28570.1 - 7.9e-08 31.9 0.0 1.9e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CAR28570.1 - 2.7e-05 23.7 0.0 0.0024 17.4 0.0 2.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CAR28570.1 - 0.017 14.8 0.0 0.035 13.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold MHC_I PF00129.18 CAR28570.1 - 0.18 11.3 0.0 0.44 10.1 0.1 1.6 2 0 0 2 2 2 0 Class I Histocompatibility antigen, domains alpha 1 and 2 Acetyltransf_1 PF00583.25 CAR28571.1 - 0.014 15.6 0.1 0.026 14.8 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family ACPS PF01648.20 CAR28572.1 - 4.6e-11 42.9 0.0 6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily APG5 PF04106.12 CAR28573.1 - 1.6e-47 162.0 0.1 2.1e-47 161.7 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 SGT1 PF07093.11 CAR28574.1 - 3.1e-18 65.6 0.1 3.1e-18 65.6 0.1 2.1 2 0 0 2 2 2 1 SGT1 protein adh_short PF00106.25 CAR28574.1 - 0.23 10.9 0.0 0.4 10.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Pkinase PF00069.25 CAR28575.1 - 2.2e-70 237.1 0.0 4.3e-70 236.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28575.1 - 1.8e-38 132.3 0.0 3e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR28575.1 - 4e-09 36.2 0.0 7.9e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CAR28575.1 - 7.6e-05 21.8 0.1 7.6e-05 21.8 0.1 3.3 3 1 1 4 4 4 1 Haspin like kinase domain Kdo PF06293.14 CAR28575.1 - 0.00087 18.7 0.8 0.18 11.1 0.2 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Mur_ligase_M PF08245.12 CAR28576.1 - 7.6e-07 29.3 0.1 3.8e-05 23.8 0.0 2.7 1 1 1 2 2 2 2 Mur ligase middle domain RRM_1 PF00076.22 CAR28577.1 - 0.0067 16.2 0.0 0.026 14.4 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.18 CAR28578.1 - 7.3e-73 245.8 3.2 3.7e-68 230.3 0.4 3.2 1 1 1 2 2 2 2 tRNA pseudouridine synthase D (TruD) NifW PF03206.14 CAR28578.1 - 0.74 10.4 3.7 2 9.0 1.3 2.5 2 0 0 2 2 2 0 Nitrogen fixation protein NifW WD40 PF00400.32 CAR28579.1 - 2.9e-33 113.3 17.1 1.1e-06 29.2 1.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR28579.1 - 7.1e-07 29.4 0.9 0.57 10.5 0.0 4.5 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR28579.1 - 0.0019 16.9 2.6 1.7 7.2 0.0 3.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CAR28579.1 - 0.011 14.5 0.3 6.4 5.4 0.0 3.5 1 1 3 4 4 4 0 Nup133 N terminal like MOZ_SAS PF01853.18 CAR28580.1 - 3.7e-83 277.6 0.5 5.4e-83 277.0 0.5 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 CAR28580.1 - 1.9e-21 75.7 0.0 4.6e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 CAR28580.1 - 2.5e-21 75.0 0.4 7e-21 73.6 0.4 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CAR28580.1 - 0.0023 18.3 0.0 0.0054 17.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CAR28580.1 - 0.0055 16.9 0.0 0.02 15.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Peptidase_M54 PF07998.11 CAR28580.1 - 0.058 13.4 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 Peptidase family M54 HTH_11 PF08279.12 CAR28580.1 - 0.24 11.4 2.6 0.45 10.5 0.2 2.5 2 0 0 2 2 2 0 HTH domain PTPA PF03095.15 CAR28581.1 - 2.9e-115 384.9 0.2 3.3e-115 384.7 0.2 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DAGAT PF03982.13 CAR28582.1 - 8.7e-79 264.5 0.3 5.3e-70 235.7 0.0 2.0 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Pkinase PF00069.25 CAR28583.1 - 2.7e-76 256.4 0.0 4.1e-76 255.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28583.1 - 1.2e-34 119.8 0.0 2e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CAR28583.1 - 8.2e-27 93.4 4.9 2.9e-14 53.1 0.2 3.5 4 0 0 4 4 4 2 FHA domain Kinase-like PF14531.6 CAR28583.1 - 9.9e-12 44.8 0.0 2.1e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 CAR28583.1 - 1.5e-09 38.0 0.2 5.8e-06 26.5 0.0 3.1 3 0 0 3 3 3 2 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 CAR28583.1 - 8.3e-06 25.3 0.0 1.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR28583.1 - 2.1e-05 24.6 0.0 0.0032 17.4 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CAR28583.1 - 0.0033 17.0 0.0 0.0064 16.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family FHA_2 PF17913.1 CAR28583.1 - 0.016 15.4 0.3 5.5 7.3 0.0 3.2 3 0 0 3 3 3 0 FHA domain CortBP2 PF09727.9 CAR28583.1 - 0.93 9.4 5.1 0.38 10.6 0.3 2.4 3 0 0 3 3 3 0 Cortactin-binding protein-2 Asp PF00026.23 CAR28584.1 - 1.7e-106 356.2 0.0 2.1e-106 355.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR28584.1 - 4.8e-16 59.5 1.8 4.6e-09 36.8 0.3 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CAR28584.1 - 0.031 14.9 0.0 2.5 8.8 0.0 2.7 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 CAR28584.1 - 0.039 14.5 0.0 3.7 8.2 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CAR28584.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Kinesin PF00225.23 CAR28585.1 - 3.3e-105 351.7 0.1 4.8e-105 351.2 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAR28585.1 - 1.3e-22 80.3 0.0 3e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding MPS2 PF17060.5 CAR28585.1 - 0.005 16.1 1.2 0.16 11.2 0.8 2.3 2 0 0 2 2 2 1 Monopolar spindle protein 2 CorA PF01544.18 CAR28585.1 - 0.019 14.3 1.4 0.036 13.4 1.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SYF2 PF08231.12 CAR28585.1 - 0.15 12.5 1.9 0.24 11.8 0.7 1.9 2 0 0 2 2 2 0 SYF2 splicing factor Fib_alpha PF08702.10 CAR28585.1 - 0.28 11.4 2.9 0.34 11.1 0.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 CAR28585.1 - 5.5 7.1 12.4 27 4.8 12.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NYD-SP28 PF14772.6 CAR28585.1 - 8.3 6.5 9.1 21 5.2 0.1 3.3 3 0 0 3 3 3 0 Sperm tail Methyltransf_15 PF09445.10 CAR28586.1 - 3.7e-59 199.0 0.0 5e-59 198.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 CAR28586.1 - 1e-05 26.1 0.0 3.1e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR28586.1 - 0.00014 21.7 0.0 0.00031 20.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 CAR28586.1 - 0.0011 18.7 0.6 0.054 13.2 0.1 2.2 1 1 1 2 2 2 1 DNA methylase CMAS PF02353.20 CAR28586.1 - 0.0012 18.3 0.0 0.0022 17.3 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CAR28586.1 - 0.026 13.8 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 CAR28586.1 - 0.031 14.9 0.0 0.15 12.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 CAR28586.1 - 0.039 13.6 0.0 0.26 10.9 0.0 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 tRNA_U5-meth_tr PF05958.11 CAR28586.1 - 0.043 12.8 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 CAR28586.1 - 0.049 13.2 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_23 PF13489.6 CAR28586.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pet20 PF08692.10 CAR28588.1 - 2e-14 54.4 10.6 2.9e-08 34.5 0.0 3.4 3 1 1 4 4 4 2 Mitochondrial protein Pet20 UMPH-1 PF05822.12 CAR28588.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) HapK PF11639.8 CAR28589.1 - 0.089 13.3 0.0 0.099 13.1 0.0 1.3 1 0 0 1 1 1 0 REDY-like protein HapK tRNA-synt_1 PF00133.22 CAR28590.1 - 9.3e-46 156.3 0.1 7.8e-38 130.1 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CAR28590.1 - 2.3e-16 59.5 0.1 6e-09 35.1 0.0 3.9 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CAR28590.1 - 4.4e-12 46.2 0.0 1e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CAR28590.1 - 1.7e-06 27.6 0.0 3.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain adh_short PF00106.25 CAR28591.1 - 1.4e-24 86.6 0.1 6.8e-20 71.3 0.0 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CAR28591.1 - 1.1e-13 51.4 0.0 8.2e-11 41.9 0.0 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR28591.1 - 0.00034 20.6 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CAR28591.1 - 0.00084 18.8 0.4 0.0044 16.4 0.4 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.18 CAR28591.1 - 0.069 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 CAR28591.1 - 0.14 11.6 0.2 0.23 10.9 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family STIMATE PF12400.8 CAR28593.1 - 9.4e-41 139.3 4.0 1.5e-40 138.6 4.0 1.3 1 0 0 1 1 1 1 STIMATE family HATPase_c_3 PF13589.6 CAR28595.1 - 1.8e-11 44.0 0.0 3.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CAR28595.1 - 1.5e-06 28.7 0.0 3.3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 CAR28595.1 - 0.00059 19.6 0.1 0.008 16.0 0.1 2.6 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CAR28595.1 - 0.0017 18.0 0.0 0.006 16.3 0.0 2.0 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain ANAPC5 PF12862.7 CAR28596.1 - 7.1e-28 96.5 4.1 9.4e-28 96.1 2.0 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_5 PF12688.7 CAR28596.1 - 0.025 14.8 1.0 6.1 7.1 0.0 3.2 3 0 0 3 3 3 0 Tetratrico peptide repeat PEN-2 PF10251.9 CAR28596.1 - 0.17 12.4 0.3 0.66 10.4 0.1 2.1 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase CLP1_P PF16575.5 CAR28597.1 - 1.4e-26 93.4 0.0 2e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 CAR28597.1 - 2.3e-24 86.0 0.0 7.3e-24 84.4 0.0 1.8 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 CAR28597.1 - 1.7e-23 82.7 0.0 2.9e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor PduV-EutP PF10662.9 CAR28597.1 - 0.00077 19.2 0.0 0.0022 17.7 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CAR28597.1 - 0.00099 19.5 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CAR28597.1 - 0.013 15.6 0.1 0.78 9.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CAR28597.1 - 0.014 15.9 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 CAR28597.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 CAR28597.1 - 0.049 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CAR28597.1 - 0.058 13.8 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 CAR28597.1 - 0.067 13.5 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CAR28597.1 - 0.11 13.0 0.1 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CAR28597.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_19 PF13245.6 CAR28597.1 - 0.14 12.5 0.0 0.57 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CAR28597.1 - 0.21 11.5 0.1 2.1 8.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_17 PF13207.6 CAR28597.1 - 0.3 11.5 0.7 12 6.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain Rhodanese PF00581.20 CAR28598.1 - 7.6e-15 55.3 0.0 3.9e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain SET PF00856.28 CAR28599.1 - 1.9e-11 44.7 0.0 4.2e-11 43.5 0.0 1.6 1 1 0 1 1 1 1 SET domain YHS PF04945.13 CAR28599.1 - 0.011 15.9 0.4 0.023 14.8 0.4 1.5 1 0 0 1 1 1 0 YHS domain Atg29_N PF18388.1 CAR28600.1 - 1.1e-16 60.4 0.2 2e-16 59.6 0.2 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain YwhD PF08741.10 CAR28600.1 - 0.092 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 YwhD family DNA_pol_B PF00136.21 CAR28601.1 - 7.8e-109 364.4 1.3 1.2e-108 363.7 1.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CAR28601.1 - 5.1e-19 68.6 0.1 2.9e-08 33.3 0.0 2.7 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CAR28601.1 - 4.5e-12 46.3 9.0 1.2e-11 44.9 9.0 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 CAR28601.1 - 0.067 13.2 3.7 0.14 12.2 3.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 CAR28601.1 - 0.19 11.8 7.5 0.034 14.1 1.6 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Tma16 PF11176.8 CAR28602.1 - 7.2e-46 155.7 7.5 8.8e-46 155.4 7.5 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 LMBR1 PF04791.16 CAR28602.1 - 0.16 10.8 3.4 0.19 10.6 3.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Mn_catalase PF05067.12 CAR28603.1 - 0.027 13.5 0.0 0.054 12.5 0.0 1.5 2 0 0 2 2 2 0 Manganese containing catalase DUF676 PF05057.14 CAR28604.1 - 7.4e-59 198.9 0.0 1.2e-58 198.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 CAR28604.1 - 0.008 15.4 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase RINT1_TIP1 PF04437.13 CAR28605.1 - 1.1e-74 252.2 20.7 1.1e-74 252.2 20.7 2.2 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Arena_nucleocap PF00843.17 CAR28605.1 - 0.013 14.5 2.0 0.014 14.3 0.3 1.9 2 0 0 2 2 2 0 Arenavirus nucleocapsid N-terminal domain PCRF PF03462.18 CAR28605.1 - 0.044 13.6 3.1 0.16 11.9 3.1 2.0 1 0 0 1 1 1 0 PCRF domain Syntaxin-6_N PF09177.11 CAR28606.1 - 0.021 15.4 0.6 0.12 12.9 0.3 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cortex-I_coil PF09304.10 CAR28606.1 - 0.057 13.6 1.1 0.13 12.5 0.1 1.8 1 1 1 2 2 2 0 Cortexillin I, coiled coil BspA_v PF18220.1 CAR28606.1 - 0.058 13.5 0.0 0.074 13.2 0.0 1.1 1 0 0 1 1 1 0 Adhesin BspA variable domain Spc7 PF08317.11 CAR28606.1 - 0.24 10.2 2.5 0.52 9.1 2.5 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein EMP24_GP25L PF01105.24 CAR28607.1 - 2.4e-06 27.6 0.2 3.7e-06 27.0 0.2 1.3 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RNase_PH PF01138.21 CAR28608.1 - 5.2e-10 39.9 0.1 7.2e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CAR28608.1 - 0.0098 15.9 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 SpoU_methylase PF00588.19 CAR28609.1 - 5.6e-25 88.2 0.0 1.1e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family PX PF00787.24 CAR28610.1 - 2.5e-22 79.0 0.1 1.6e-21 76.4 0.0 2.3 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CAR28610.1 - 9.5e-06 25.3 11.5 0.00031 20.4 2.6 2.3 2 0 0 2 2 2 2 Vps5 C terminal like DUF5082 PF16888.5 CAR28610.1 - 0.00078 19.7 3.7 0.00085 19.6 1.2 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF5082) DUF1843 PF08898.10 CAR28610.1 - 1.2 9.7 4.0 1.4 9.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) YtxH PF12732.7 CAR28610.1 - 3.8 8.1 4.9 1.1 9.9 0.1 2.5 2 0 0 2 2 2 0 YtxH-like protein IATP PF04568.12 CAR28610.1 - 4.8 7.7 6.8 4.4 7.8 3.2 2.6 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP CCDC-167 PF15188.6 CAR28610.1 - 8.1 6.9 16.7 0.11 12.8 2.0 3.0 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 adh_short PF00106.25 CAR28611.1 - 9.8e-40 136.1 0.0 1.3e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR28611.1 - 1.7e-26 93.2 0.0 2.4e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR28611.1 - 3.5e-07 30.3 0.2 5.5e-06 26.4 0.2 2.3 1 1 0 1 1 1 1 KR domain Iwr1 PF08574.10 CAR28612.1 - 1.8e-12 48.1 17.7 1.8e-12 48.1 17.7 3.1 2 0 0 2 2 2 1 Transcription factor Iwr1 Ribosomal_L6 PF00347.23 CAR28613.1 - 2.3e-26 92.3 7.6 4.1e-13 49.8 1.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 AdoMet_MTase PF07757.13 CAR28614.1 - 5e-41 139.5 0.0 1.1e-40 138.5 0.0 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 CAR28614.1 - 0.05 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain ELK PF03789.13 CAR28614.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 ELK domain Pkinase PF00069.25 CAR28615.1 - 5.8e-76 255.3 0.0 6.6e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28615.1 - 3.4e-37 128.1 0.0 5.2e-37 127.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR28615.1 - 0.00087 18.7 0.0 0.0015 17.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CAR28615.1 - 0.008 15.2 0.1 0.049 12.6 0.0 2.2 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CAR28615.1 - 0.03 14.2 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family ApbA_C PF08546.11 CAR28617.1 - 2.4e-06 27.7 0.0 4.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF4763 PF15960.5 CAR28617.1 - 0.0048 16.2 5.9 0.0048 16.2 5.9 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4763) Pil1 PF13805.6 CAR28617.1 - 0.011 15.2 3.7 0.022 14.2 3.7 1.4 1 0 0 1 1 1 0 Eisosome component PIL1 RcbX PF02341.15 CAR28617.1 - 0.045 14.0 0.5 0.1 12.9 0.5 1.6 1 0 0 1 1 1 0 RbcX protein UPF0242 PF06785.11 CAR28617.1 - 2.1 8.4 17.6 0.14 12.3 8.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 CAR28617.1 - 2.1 8.7 18.6 4.4 7.7 2.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 CAR28617.1 - 4.9 5.9 17.9 0.078 11.8 7.3 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Mod_r PF07200.13 CAR28617.1 - 6.2 6.9 17.0 6.1 6.9 9.9 2.6 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4124 PF13511.6 CAR28617.1 - 7.8 6.9 10.8 37 4.7 9.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4124) Med9 PF07544.13 CAR28617.1 - 9.9 6.3 13.2 16 5.7 0.6 3.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 NAC PF01849.18 CAR28618.1 - 8.5e-17 60.9 0.1 2e-16 59.7 0.1 1.7 1 0 0 1 1 1 1 NAC domain Glyco_hydro_97 PF10566.9 CAR28618.1 - 0.03 13.6 0.1 0.034 13.4 0.1 1.1 1 0 0 1 1 1 0 Glycoside hydrolase 97 zf-C2H2 PF00096.26 CAR28619.1 - 2.8e-09 36.9 8.8 0.00026 21.3 4.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR28619.1 - 7.3e-08 32.6 6.6 0.0019 18.9 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CAR28619.1 - 0.00061 19.7 4.0 0.45 10.6 0.1 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CAR28619.1 - 0.003 16.9 0.4 1.6 8.3 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain zf-C2H2_11 PF16622.5 CAR28619.1 - 0.0047 16.6 4.9 0.39 10.5 0.1 2.3 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 CAR28619.1 - 0.0057 16.9 1.8 1.5 9.2 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 CAR28619.1 - 0.0069 16.8 1.0 1.5 9.4 0.1 2.4 2 0 0 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 CAR28619.1 - 0.018 15.4 5.2 0.068 13.6 0.6 3.0 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CAR28619.1 - 0.032 14.9 0.2 0.33 11.6 0.1 2.1 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats tRNA-synt_1 PF00133.22 CAR28621.1 - 3.2e-159 531.0 0.0 4.6e-159 530.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CAR28621.1 - 1.9e-19 69.7 0.0 4.8e-11 42.0 0.0 3.8 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CAR28621.1 - 2e-17 63.6 2.0 2.4e-17 63.3 0.4 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 CAR28621.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 MFS_1 PF07690.16 CAR28622.1 - 4.1e-30 104.9 26.9 4.1e-30 104.9 26.9 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CAR28622.1 - 4.6e-05 22.9 3.0 4.6e-05 22.9 3.0 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB FLILHELTA PF10306.9 CAR28623.1 - 1.4e-23 83.1 0.0 2.5e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF2740 PF10872.8 CAR28623.1 - 0.029 14.2 0.5 0.06 13.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) Pkinase PF00069.25 CAR28624.1 - 6.5e-56 189.6 0.0 1.1e-54 185.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28624.1 - 3.9e-26 91.9 0.0 4.3e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR28624.1 - 0.025 13.5 0.2 0.04 12.9 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RRM_1 PF00076.22 CAR28625.1 - 1.1e-59 198.1 0.5 2.8e-17 62.3 0.1 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CAR28625.1 - 2.2e-07 31.3 7.6 1 9.5 0.0 7.3 4 4 4 8 8 8 3 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 CAR28625.1 - 4.9e-07 29.8 0.1 0.0021 18.1 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif CENP-N PF05238.13 CAR28626.1 - 2e-94 317.3 0.0 2.5e-94 317.0 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like FG-GAP_2 PF14312.6 CAR28626.1 - 0.092 13.0 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 FG-GAP repeat Vps16_C PF04840.12 CAR28627.1 - 3.3e-89 299.1 5.7 6.4e-89 298.1 5.7 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 CAR28627.1 - 3.4e-71 240.2 1.2 4.6e-71 239.7 1.2 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Skp1_POZ PF03931.15 CAR28628.1 - 1.6e-16 60.2 0.0 6.5e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 CAR28628.1 - 0.0022 18.2 0.0 0.0058 16.8 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Tyosinase_C PF18132.1 CAR28628.1 - 0.11 13.2 0.0 0.13 12.9 0.0 1.3 1 1 0 1 1 1 0 Tyosinase C-terminal domain CLTH PF10607.9 CAR28629.1 - 4.2e-13 49.4 0.9 4.2e-13 49.4 0.9 2.6 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CAR28629.1 - 2e-05 24.5 1.1 2e-05 24.5 1.1 2.0 2 0 0 2 2 2 1 RING-type zinc-finger DegS PF05384.11 CAR28629.1 - 0.0018 17.8 4.2 0.0038 16.7 4.2 1.5 1 0 0 1 1 1 1 Sensor protein DegS zf-RING_2 PF13639.6 CAR28629.1 - 0.039 14.3 1.1 0.11 12.8 1.1 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 CAR28629.1 - 0.044 13.8 0.5 0.13 12.3 0.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain SLIDE PF09111.10 CAR28629.1 - 0.061 13.4 3.3 0.14 12.2 3.3 1.6 1 0 0 1 1 1 0 SLIDE PilP PF04351.13 CAR28629.1 - 0.061 13.3 0.2 0.2 11.6 0.2 1.8 1 0 0 1 1 1 0 Pilus assembly protein, PilP Mer2 PF09074.10 CAR28629.1 - 0.13 12.0 5.6 0.34 10.7 5.6 1.7 1 0 0 1 1 1 0 Mer2 ISG65-75 PF11727.8 CAR28629.1 - 0.15 11.3 6.3 0.23 10.6 6.3 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein Atg14 PF10186.9 CAR28629.1 - 0.18 10.8 8.8 0.032 13.3 5.3 1.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2HE PF16278.5 CAR28629.1 - 0.31 11.5 5.9 0.38 11.2 1.6 2.9 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger YscO PF07321.12 CAR28629.1 - 0.74 9.8 7.2 2 8.3 7.2 1.7 1 1 0 1 1 1 0 Type III secretion protein YscO RRF PF01765.19 CAR28629.1 - 2.8 7.9 8.7 2.6 8.0 6.8 1.8 1 1 1 2 2 2 0 Ribosome recycling factor Sgf11_N PF18519.1 CAR28630.1 - 1.1e-24 85.7 0.3 1.6e-24 85.2 0.3 1.3 1 0 0 1 1 1 1 SAGA-associated factor 11 N-terminal domain Sgf11 PF08209.11 CAR28630.1 - 1.2e-16 59.9 3.5 2e-16 59.3 3.5 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-U11-48K PF05253.12 CAR28630.1 - 0.056 13.4 0.0 5.1 7.1 0.0 2.4 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger Catalase PF00199.19 CAR28631.1 - 1.9e-182 606.6 0.4 2.5e-182 606.2 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CAR28631.1 - 1.2e-10 41.5 0.1 4.2e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive EF1G PF00647.19 CAR28632.1 - 1e-43 147.7 0.1 1.7e-43 147.0 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CAR28632.1 - 7e-11 42.2 0.5 1.5e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CAR28632.1 - 1.4e-08 34.9 3.7 6e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CAR28632.1 - 6.4e-06 26.1 0.0 1.3e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CAR28632.1 - 0.0079 16.4 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DDHD PF02862.17 CAR28633.1 - 0.41 10.8 8.0 0.46 10.6 0.7 2.2 2 0 0 2 2 2 0 DDHD domain YABBY PF04690.13 CAR28633.1 - 5.4 7.5 5.7 2.9 8.4 0.6 2.4 2 1 0 2 2 2 0 YABBY protein CPSF100_C PF13299.6 CAR28633.1 - 6 7.0 14.3 2.8 8.1 4.6 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Anp1 PF03452.14 CAR28634.1 - 4e-106 354.3 0.1 4.8e-106 354.0 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 CAR28634.1 - 0.00025 20.9 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Alk_phosphatase PF00245.20 CAR28635.1 - 1.4e-122 409.7 0.3 1.6e-122 409.4 0.3 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CAR28635.1 - 6.8e-05 22.4 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF5619 PF18505.1 CAR28635.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) Arf PF00025.21 CAR28636.1 - 2.9e-48 163.6 0.1 3.7e-48 163.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CAR28636.1 - 1.2e-14 54.2 0.0 1.4e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR28636.1 - 3.8e-14 53.0 0.0 5.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAR28636.1 - 1.4e-13 50.7 0.0 3.9e-13 49.2 0.0 1.5 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CAR28636.1 - 4.2e-12 45.9 0.1 3e-08 33.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CAR28636.1 - 2.7e-10 40.0 0.0 3.2e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR28636.1 - 7.7e-08 32.1 0.0 1.6e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAR28636.1 - 3.4e-07 30.4 0.0 5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CAR28636.1 - 0.00082 19.7 0.1 0.0067 16.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain MMR_HSR1_Xtn PF16897.5 CAR28636.1 - 0.022 14.8 0.0 0.035 14.1 0.0 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Septin PF00735.18 CAR28636.1 - 0.14 11.5 0.1 0.37 10.0 0.1 1.6 2 0 0 2 2 2 0 Septin Thymidylate_kin PF02223.17 CAR28636.1 - 0.16 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase cwf21 PF08312.12 CAR28637.1 - 7.9e-15 54.7 5.1 1.2e-14 54.2 5.1 1.3 1 0 0 1 1 1 1 cwf21 domain Trans_reg_C PF00486.28 CAR28637.1 - 0.1 12.7 0.7 4.9 7.3 0.1 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal GTP-bdg_M PF16360.5 CAR28637.1 - 2.3 8.9 8.0 1.1e+02 3.4 8.0 2.5 1 1 0 1 1 1 0 GTP-binding GTPase Middle Region ODC_AZ PF02100.17 CAR28638.1 - 1.2e-06 28.4 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Glyco_transf_15 PF01793.16 CAR28639.1 - 5.7e-131 436.6 19.1 7.5e-131 436.2 19.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.9 CAR28639.1 - 0.037 12.3 5.0 0.046 12.0 5.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_S49_N PF08496.10 CAR28639.1 - 0.079 13.0 0.0 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal SRRM_C PF15230.6 CAR28639.1 - 0.15 12.7 3.9 0.3 11.7 3.9 1.5 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus Presenilin PF01080.17 CAR28639.1 - 0.17 10.6 0.7 0.21 10.3 0.7 1.1 1 0 0 1 1 1 0 Presenilin Sulfotransfer_3 PF13469.6 CAR28639.1 - 0.28 11.5 1.4 3.3 8.0 0.3 2.6 1 1 1 2 2 2 0 Sulfotransferase family TPR_1 PF00515.28 CAR28640.1 - 1e-11 44.1 12.4 0.00082 19.1 0.5 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR28640.1 - 2.3e-10 39.8 10.3 0.0021 18.0 0.5 3.9 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CAR28640.1 - 2.4e-06 27.1 3.1 0.0095 15.6 0.3 2.7 2 0 0 2 2 2 2 TPR repeat ANAPC3 PF12895.7 CAR28640.1 - 3.2e-06 27.3 7.7 1.7e-05 25.0 3.3 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CAR28640.1 - 4.2e-06 27.0 0.8 0.1 12.9 0.1 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR28640.1 - 4.7e-06 26.6 5.4 0.00069 19.6 0.1 4.0 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 CAR28640.1 - 1.1e-05 25.8 0.8 0.0016 18.9 0.1 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR28640.1 - 2.3e-05 24.3 7.3 0.056 13.7 0.2 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR28640.1 - 9.1e-05 22.6 2.7 0.00064 19.9 1.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAR28640.1 - 0.0016 19.1 0.0 6.9 7.8 0.0 3.8 2 2 1 3 3 3 1 Tetratricopeptide repeat zf-ZPR1 PF03367.13 CAR28640.1 - 0.0084 16.0 0.3 0.087 12.7 0.2 2.5 2 0 0 2 2 2 1 ZPR1 zinc-finger domain TPR_10 PF13374.6 CAR28640.1 - 0.038 13.9 0.1 12 5.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CAR28640.1 - 0.049 13.6 1.0 0.33 10.9 0.1 2.6 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 CAR28640.1 - 0.052 14.2 0.0 5.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ThiS PF02597.20 CAR28640.1 - 0.22 12.2 0.9 1.8 9.3 0.0 2.8 3 1 0 3 3 3 0 ThiS family TPR_6 PF13174.6 CAR28640.1 - 0.84 10.4 5.7 1.6 9.5 0.2 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat INCENP_ARK-bind PF03941.15 CAR28641.1 - 3.5e-17 62.1 0.5 8.3e-17 60.9 0.5 1.7 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region EcsC PF12787.7 CAR28641.1 - 0.14 11.9 1.0 0.29 10.8 1.0 1.5 1 0 0 1 1 1 0 EcsC protein family Borrelia_P83 PF05262.11 CAR28641.1 - 7.4 4.9 12.7 11 4.3 12.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-CCCH PF00642.24 CAR28643.1 - 1.7e-10 40.5 11.1 4.2e-05 23.4 2.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAR28643.1 - 3.2e-10 39.7 16.2 2.2e-05 24.4 3.0 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 CAR28643.1 - 6.8e-08 33.2 8.4 2.5e-05 24.9 1.6 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 CAR28643.1 - 4e-07 29.7 11.7 0.0024 17.6 0.8 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CAR28643.1 - 0.0016 18.6 5.2 0.0021 18.3 3.7 1.9 1 1 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 CAR28643.1 - 0.011 16.2 13.2 0.45 11.1 1.6 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger SWI-SNF_Ssr4 PF08549.10 CAR28643.1 - 0.045 12.4 0.1 0.045 12.4 0.1 2.2 3 0 0 3 3 3 0 Fungal domain of unknown function (DUF1750) LRR_6 PF13516.6 CAR28644.1 - 0.00025 20.9 7.5 0.25 11.5 0.1 4.1 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 CAR28644.1 - 0.021 15.2 5.2 6.9 7.2 0.2 3.9 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) Lge1 PF11488.8 CAR28645.1 - 8.8e-24 83.5 5.8 1.2e-23 83.1 5.8 1.2 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 adh_short PF00106.25 CAR28646.1 - 1.7e-33 115.8 0.0 2.3e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR28646.1 - 7.7e-19 68.2 0.0 1.1e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CAR28646.1 - 5.6e-07 29.6 0.1 2.7e-06 27.4 0.1 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CAR28646.1 - 0.0018 17.5 0.1 0.0025 17.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 CAR28646.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 CAR28647.1 - 7.1e-72 241.9 0.0 8.1e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28647.1 - 3.3e-33 115.1 0.0 4.1e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR28647.1 - 2.1e-05 24.0 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CAR28647.1 - 0.0016 17.4 0.1 0.0095 14.9 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CAR28647.1 - 0.005 16.8 0.2 0.022 14.7 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CAR28647.1 - 0.019 14.3 0.2 0.057 12.8 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gly_transf_sug PF04488.15 CAR28648.1 - 3.4e-20 72.5 0.0 6.3e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 CAR28648.1 - 0.65 9.2 1.2 1.2 8.4 0.2 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2401 PF10287.9 CAR28649.1 - 4.2e-95 317.7 1.5 4.2e-95 317.7 1.5 1.7 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CAR28649.1 - 1.4e-28 99.1 1.8 1.9e-28 98.7 0.1 2.2 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Sporozoite_P67 PF05642.11 CAR28649.1 - 0.1 10.7 28.0 0.15 10.1 28.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SPX PF03105.19 CAR28649.1 - 0.89 9.4 7.9 1.1 9.1 7.9 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CAR28649.1 - 3.3 6.4 5.9 4.3 6.1 5.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ABC2_membrane PF01061.24 CAR28650.1 - 5.1e-66 222.1 55.4 5.7e-38 130.4 15.5 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CAR28650.1 - 3e-35 121.7 0.0 4.3e-17 62.9 0.0 2.6 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 CAR28650.1 - 4.3e-31 106.7 5.5 6.7e-26 90.0 0.1 3.2 2 0 0 2 2 2 2 CDR ABC transporter RsgA_GTPase PF03193.16 CAR28650.1 - 1.3e-07 31.6 0.0 0.00016 21.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC_trans_N PF14510.6 CAR28650.1 - 4.3e-07 30.5 0.0 9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CAR28650.1 - 1.1e-05 25.8 0.0 0.03 14.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 CAR28650.1 - 6.3e-05 22.2 0.9 6.3e-05 22.2 0.9 3.0 3 1 0 3 3 3 1 ABC-2 family transporter protein SMC_N PF02463.19 CAR28650.1 - 7.9e-05 22.2 0.0 0.57 9.6 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CAR28650.1 - 0.00023 21.5 0.0 0.082 13.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CAR28650.1 - 0.00063 19.8 0.2 0.8 9.8 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CAR28650.1 - 0.00081 19.1 0.4 0.1 12.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CAR28650.1 - 0.0038 16.8 0.1 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CAR28650.1 - 0.0053 17.3 0.0 0.18 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAR28650.1 - 0.0054 16.5 0.1 0.75 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CAR28650.1 - 0.0059 15.9 0.0 2.1 7.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 CAR28650.1 - 0.0069 16.2 0.0 4.7 6.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Ploopntkinase3 PF18751.1 CAR28650.1 - 0.0072 16.3 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NACHT PF05729.12 CAR28650.1 - 0.0094 15.9 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 CAR28650.1 - 0.014 15.6 0.0 0.55 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CAR28650.1 - 0.02 14.8 0.0 22 4.9 0.0 3.2 3 0 0 3 3 3 0 NTPase dNK PF01712.19 CAR28650.1 - 0.051 13.4 0.1 1.5 8.6 0.0 2.9 3 0 0 3 3 3 0 Deoxynucleoside kinase TsaE PF02367.17 CAR28650.1 - 0.054 13.5 0.3 0.17 11.9 0.2 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CAR28650.1 - 0.062 13.7 0.0 3.7 8.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 CAR28650.1 - 0.17 12.4 0.0 0.51 10.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 CAR28650.1 - 0.18 11.4 0.7 1 8.9 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC2_membrane PF01061.24 CAR28651.1 - 1.2e-65 220.9 51.1 2e-36 125.4 11.7 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CAR28651.1 - 9.6e-36 123.3 0.0 6.3e-17 62.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CAR28651.1 - 1.8e-34 117.5 3.8 3.1e-28 97.5 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter RsgA_GTPase PF03193.16 CAR28651.1 - 4.6e-07 29.9 0.0 0.00017 21.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_trans_N PF14510.6 CAR28651.1 - 1.4e-06 28.8 0.0 3.1e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CAR28651.1 - 1.3e-05 25.7 0.6 0.03 14.7 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 CAR28651.1 - 3e-05 23.6 0.0 0.22 10.9 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 CAR28651.1 - 0.0001 21.5 3.7 0.0001 21.5 3.7 3.1 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_25 PF13481.6 CAR28651.1 - 0.00041 20.0 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CAR28651.1 - 0.00051 20.1 0.2 0.8 9.8 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CAR28651.1 - 0.00055 20.2 0.1 0.082 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CAR28651.1 - 0.00079 19.1 0.1 0.1 12.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 CAR28651.1 - 0.0032 17.2 0.7 0.75 9.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CAR28651.1 - 0.0051 16.8 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 CAR28651.1 - 0.0063 16.4 0.0 4.7 6.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CAR28651.1 - 0.0071 16.9 0.0 0.18 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CAR28651.1 - 0.011 15.0 0.0 2.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 CAR28651.1 - 0.011 15.9 0.0 0.55 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 CAR28651.1 - 0.013 15.4 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 CAR28651.1 - 0.03 14.7 0.0 3.7 8.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 CAR28651.1 - 0.034 14.0 0.0 22 4.9 0.0 3.2 3 0 0 3 3 3 0 NTPase TsaE PF02367.17 CAR28651.1 - 0.062 13.3 0.4 0.17 11.9 0.2 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 CAR28651.1 - 0.15 12.6 0.0 0.51 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CAR28651.1 - 0.25 10.9 0.8 1 8.9 0.3 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Tom22 PF04281.13 CAR28651.1 - 0.25 11.1 1.0 0.5 10.1 1.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Exo5 PF09810.9 CAR28652.1 - 3.5e-59 201.1 0.0 4.6e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 CAR28652.1 - 0.011 15.6 3.4 0.38 10.6 3.4 2.7 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF3271 PF11675.8 CAR28652.1 - 0.019 14.2 1.8 0.23 10.7 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3271) Glutaredoxin PF00462.24 CAR28653.1 - 2.4e-18 66.1 0.0 6e-18 64.8 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin Amidase PF01425.21 CAR28654.1 - 5.2e-96 322.3 0.0 7.3e-96 321.9 0.0 1.2 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 CAR28654.1 - 2.6e-87 292.8 0.0 4.6e-87 292.0 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 CAR28654.1 - 3.8e-63 212.8 0.0 1.6e-62 210.8 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 CAR28654.1 - 2.2e-43 148.4 0.0 4e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 CAR28654.1 - 1.1e-39 135.4 0.0 3.1e-39 133.9 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CAR28654.1 - 1.4e-33 115.2 0.0 4.8e-33 113.5 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CAR28654.1 - 5.5e-18 64.6 1.9 8.8e-18 63.9 0.6 2.1 2 0 0 2 2 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CAR28654.1 - 1.7e-10 40.8 0.0 3.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CAR28654.1 - 0.00045 19.8 0.0 0.00088 18.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CAR28654.1 - 0.00095 18.9 6.3 0.012 15.4 0.4 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CAR28654.1 - 0.0017 18.4 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 CAR28654.1 - 0.012 15.6 0.1 0.08 12.9 0.0 2.2 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 CAR28654.1 - 0.033 14.9 0.1 0.086 13.6 0.1 1.8 1 0 0 1 1 1 0 HlyD family secretion protein GCV_H PF01597.19 CAR28654.1 - 0.048 13.6 0.1 2.5 8.0 0.1 2.8 2 0 0 2 2 2 0 Glycine cleavage H-protein NQRA PF05896.11 CAR28654.1 - 0.11 12.0 0.1 0.21 11.0 0.1 1.4 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_5 PF13549.6 CAR28654.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain FTR1 PF03239.14 CAR28655.1 - 1.1e-94 317.1 5.2 1.2e-94 316.9 5.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Amidase_5 PF05382.13 CAR28655.1 - 0.0065 16.4 0.9 0.011 15.6 0.4 1.6 2 0 0 2 2 2 1 Bacteriophage peptidoglycan hydrolase S_2TMBeta PF18153.1 CAR28655.1 - 0.088 12.6 0.5 0.23 11.2 0.5 1.7 1 0 0 1 1 1 0 SMODS-associating 2TM, beta-strand rich effector domain CorA PF01544.18 CAR28656.1 - 6.3e-07 29.0 7.6 1.5e-06 27.8 7.6 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein YrhC PF14143.6 CAR28656.1 - 0.13 12.3 0.9 0.26 11.4 0.9 1.5 1 0 0 1 1 1 0 YrhC-like protein Glyco_transf_15 PF01793.16 CAR28657.1 - 1.2e-122 409.3 7.5 1.4e-122 409.0 7.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Abhydrolase_1 PF00561.20 CAR28658.1 - 8.7e-27 94.4 0.1 1.4e-26 93.7 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR28658.1 - 1e-21 78.6 0.0 1.3e-21 78.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR28658.1 - 7.4e-15 54.9 0.0 3.3e-14 52.8 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 CAR28658.1 - 3.7e-06 26.7 0.3 1.3e-05 24.9 0.3 1.8 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 CAR28658.1 - 1.3e-05 25.1 0.0 3.4e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase DUF1749 PF08538.10 CAR28658.1 - 4.6e-05 22.7 0.0 0.00071 18.8 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1749) PGAP1 PF07819.13 CAR28658.1 - 8.6e-05 22.4 0.0 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_2 PF02230.16 CAR28658.1 - 0.00017 21.5 0.0 2.2 8.0 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase LCAT PF02450.15 CAR28658.1 - 0.00029 20.1 0.0 0.0005 19.4 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 CAR28658.1 - 0.0039 16.6 0.0 0.056 12.8 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_4 PF08386.10 CAR28658.1 - 0.011 15.9 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein DUF900 PF05990.12 CAR28658.1 - 0.011 15.2 0.0 0.03 13.8 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.7 CAR28658.1 - 0.011 15.5 0.0 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 CAR28658.1 - 0.014 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 CAR28658.1 - 0.042 13.7 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 CAR28658.1 - 0.05 13.7 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Ndr PF03096.14 CAR28658.1 - 0.052 12.2 0.1 0.28 9.8 0.1 1.9 1 1 0 1 1 1 0 Ndr family VirJ PF06057.11 CAR28658.1 - 0.15 11.9 0.1 0.74 9.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Ferric_reduct PF01794.19 CAR28659.1 - 9.4e-22 77.5 19.5 2.2e-21 76.2 15.8 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CAR28659.1 - 2.5e-20 73.2 0.9 5.9e-20 72.0 0.1 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CAR28659.1 - 2.6e-13 50.0 0.0 6.5e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Polysacc_synt_C PF14667.6 CAR28659.1 - 2.4 8.2 9.8 6.7 6.8 9.8 1.8 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain PRANC PF09372.10 CAR28660.1 - 0.0011 19.2 0.2 0.0011 19.2 0.2 2.2 2 0 0 2 2 2 1 PRANC domain F-box-like PF12937.7 CAR28660.1 - 0.0028 17.5 0.2 0.0086 15.9 0.0 2.0 2 0 0 2 2 2 1 F-box-like Apt1 PF10351.9 CAR28660.1 - 9.8 4.9 12.4 0.24 10.2 5.9 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain NIF PF03031.18 CAR28661.1 - 2.1e-41 141.3 0.0 3.3e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CTI PF06934.11 CAR28661.1 - 0.0056 15.3 3.4 0.0079 14.8 3.4 1.2 1 0 0 1 1 1 1 Fatty acid cis/trans isomerase (CTI) NeA_P2 PF12312.8 CAR28661.1 - 0.1 12.1 0.4 0.18 11.2 0.4 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Pro_isomerase PF00160.21 CAR28662.1 - 7.4e-05 23.1 0.0 0.00091 19.5 0.0 2.1 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 CAR28663.1 - 2.7e-37 128.6 0.0 2.2e-18 66.6 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28663.1 - 1.6e-09 37.5 0.1 4.8e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR28663.1 - 0.0011 17.8 0.0 0.0036 16.1 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 CAR28663.1 - 0.13 11.8 0.0 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 RIO1 family VPS28 PF03997.12 CAR28664.1 - 1.4e-60 204.2 0.0 4.7e-60 202.5 0.0 1.7 1 1 0 1 1 1 1 VPS28 protein MCM PF00493.23 CAR28666.1 - 1e-102 342.0 0.0 1.7e-102 341.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR28666.1 - 3.7e-31 107.6 0.6 6.7e-31 106.8 0.6 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAR28666.1 - 2.4e-21 76.0 1.4 6.9e-21 74.5 0.9 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CAR28666.1 - 6.6e-16 58.8 0.6 2.6e-15 56.9 0.6 2.1 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAR28666.1 - 2.5e-07 30.3 0.0 2.9e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CAR28666.1 - 1.9e-05 24.7 0.0 7.7e-05 22.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 CAR28666.1 - 0.00063 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase_C PF13335.6 CAR28666.1 - 0.0026 18.3 0.2 0.014 16.0 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal RcpC PF16976.5 CAR28666.1 - 0.087 12.9 2.2 0.89 9.6 0.1 2.9 2 1 0 3 3 3 0 Flp pilus assembly protein RcpC/CpaB AAA_16 PF13191.6 CAR28666.1 - 0.11 12.9 0.3 5.3 7.4 0.1 3.4 4 1 0 4 4 4 0 AAA ATPase domain NUP PF06516.11 CAR28667.1 - 2e-118 395.2 1.7 2.8e-118 394.7 1.7 1.2 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) VP_N-CPKC PF11475.8 CAR28667.1 - 0.92 9.5 3.6 1 9.3 0.1 2.6 2 0 0 2 2 2 0 Virion protein N terminal domain DUF4971 PF16341.5 CAR28667.1 - 4 7.3 11.0 4.7 7.0 7.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4971) WD40 PF00400.32 CAR28668.1 - 2.1e-17 63.1 29.6 0.00077 20.2 0.3 7.4 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR28668.1 - 0.00023 21.4 0.0 0.57 10.5 0.0 4.4 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CAR28668.1 - 0.0028 18.1 0.6 1.8 9.2 0.0 3.6 3 1 0 3 3 3 1 PQQ-like domain PQQ_2 PF13360.6 CAR28668.1 - 0.021 14.4 0.1 0.82 9.2 0.0 2.4 2 1 0 2 2 2 0 PQQ-like domain Nup160 PF11715.8 CAR28668.1 - 0.062 11.9 2.5 0.58 8.7 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Frtz PF11768.8 CAR28668.1 - 0.15 10.4 0.0 0.28 9.5 0.0 1.4 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz SlyX PF04102.12 CAR28668.1 - 0.15 12.7 0.1 0.38 11.4 0.1 1.6 1 0 0 1 1 1 0 SlyX V_ATPase_I PF01496.19 CAR28669.1 - 4.3e-299 994.1 0.0 4.9e-299 993.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CCDC85 PF10226.9 CAR28669.1 - 0.061 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 CCDC85 family DUF16 PF01519.16 CAR28669.1 - 0.28 11.7 2.0 0.61 10.6 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function DUF16 GHMP_kinases_N PF00288.26 CAR28670.1 - 2.3e-19 69.4 0.2 6.2e-19 68.0 0.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CAR28670.1 - 3.2e-06 27.4 0.0 8.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 CAR28670.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Mtc PF03820.17 CAR28671.1 - 3.8e-122 407.2 0.2 4.3e-122 407.0 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier NLE PF08154.12 CAR28672.1 - 4.1e-22 78.5 0.2 7.9e-22 77.6 0.2 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40 PF00400.32 CAR28672.1 - 5.6e-22 77.6 12.5 1.5e-05 25.6 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 CAR28672.1 - 7.2e-07 28.2 5.7 0.0015 17.2 0.3 3.3 1 1 0 3 3 3 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CAR28672.1 - 0.021 14.2 0.3 0.79 9.0 0.1 2.6 2 1 1 3 3 3 0 WD40-like domain N2227 PF07942.12 CAR28673.1 - 7.4e-61 205.7 0.0 1.1e-60 205.1 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein DUF4458 PF14660.6 CAR28673.1 - 0.036 14.3 0.1 0.1 12.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4458) RAB3GAP2_C PF14656.6 CAR28673.1 - 0.095 10.9 0.5 6 5.0 0.2 2.1 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Methyltransf_25 PF13649.6 CAR28673.1 - 0.2 12.4 0.1 24 5.7 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Tubulin_3 PF14881.6 CAR28674.1 - 7.8e-20 71.3 0.2 1.3e-19 70.5 0.2 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CAR28674.1 - 1.4e-16 60.9 0.4 2.6e-16 60.0 0.4 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 CAR28674.1 - 0.0095 16.1 0.0 0.062 13.5 0.0 2.1 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain IPPT PF01715.17 CAR28675.1 - 6.3e-68 229.0 3.1 1.2e-67 228.1 3.1 1.4 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 CAR28675.1 - 5.8e-06 25.9 1.1 0.00049 19.6 0.0 3.1 2 1 1 3 3 3 1 Isopentenyl transferase AAA_33 PF13671.6 CAR28675.1 - 5.3e-05 23.4 0.0 0.00019 21.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CAR28675.1 - 0.0011 19.5 0.4 0.0059 17.2 0.3 2.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CAR28675.1 - 0.032 14.8 0.2 0.16 12.5 0.0 2.2 2 1 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 CAR28675.1 - 0.035 14.0 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase Hpr_kinase_C PF07475.12 CAR28675.1 - 0.045 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 CAR28675.1 - 0.089 13.2 0.3 0.25 11.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase CbiA PF01656.23 CAR28675.1 - 0.2 11.7 0.8 0.41 10.7 0.6 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-met PF12874.7 CAR28675.1 - 0.43 11.0 2.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type BRO1 PF03097.18 CAR28676.1 - 1.4e-96 323.7 0.5 1.4e-96 323.7 0.5 1.5 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CAR28676.1 - 3.3e-26 92.3 12.5 2.1e-13 50.3 0.7 2.7 2 0 0 2 2 2 2 ALIX V-shaped domain binding to HIV RIH_assoc PF08454.11 CAR28677.1 - 0.17 11.7 2.1 3.9 7.4 0.1 2.9 2 0 0 2 2 2 0 RyR and IP3R Homology associated Noelin-1 PF12308.8 CAR28677.1 - 0.34 10.9 6.1 1.3 9.1 0.1 3.1 4 0 0 4 4 4 0 Neurogenesis glycoprotein Get5_C PF18514.1 CAR28677.1 - 0.36 10.6 1.1 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Get5 C-terminal domain Myb_DNA-binding PF00249.31 CAR28678.1 - 2.1e-20 72.6 0.8 2.4e-09 37.2 0.4 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CAR28678.1 - 2.4e-19 69.3 1.8 2.9e-11 43.4 1.0 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 CAR28678.1 - 8e-07 28.9 4.1 8e-07 28.9 4.1 2.8 1 1 1 3 3 3 1 pre-mRNA splicing factor component Rap1_C PF11626.8 CAR28678.1 - 0.032 14.3 1.2 0.21 11.7 0.1 2.9 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Glycos_transf_3 PF00591.21 CAR28679.1 - 2.3e-85 286.2 0.0 3.1e-85 285.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 CAR28679.1 - 3.6e-13 49.2 0.0 6.2e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Spc110_C PF18520.1 CAR28680.1 - 2.3e-23 81.5 2.5 1e-22 79.5 0.2 3.4 2 0 0 2 2 2 1 Spindle pole body component 110 C-terminal domain GAS PF13851.6 CAR28680.1 - 1.4e-05 24.5 44.6 9.9e-05 21.8 8.8 6.3 1 1 5 6 6 6 2 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 CAR28680.1 - 3.4e-05 23.9 6.3 3.4e-05 23.9 6.3 10.0 1 1 7 8 8 8 2 Centrosomin N-terminal motif 1 TPR_MLP1_2 PF07926.12 CAR28680.1 - 0.0077 16.3 20.1 0.0077 16.3 20.1 8.6 3 2 5 8 8 8 1 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 CAR28680.1 - 0.0078 16.5 13.5 0.0078 16.5 13.5 6.2 1 1 5 6 6 6 3 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 CAR28680.1 - 8.2 5.9 97.1 1.2 8.6 14.3 5.6 1 1 3 5 5 5 0 Mechanosensitive ion channel porin domain Arc_PepC PF06819.11 CAR28681.1 - 0.0072 16.4 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 Archaeal Peptidase A24 C-terminal Domain Baculo_gp41 PF04700.12 CAR28681.1 - 0.057 13.2 1.4 0.097 12.4 0.9 1.5 1 1 1 2 2 2 0 Structural glycoprotein p40/gp41 conserved region UL11 PF11094.8 CAR28681.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Membrane-associated tegument protein BORCS6 PF10157.9 CAR28681.1 - 0.073 13.3 0.2 0.1 12.8 0.2 1.4 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 TPPII_N PF12583.8 CAR28681.1 - 0.13 12.8 0.2 0.17 12.5 0.2 1.1 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal VHS PF00790.19 CAR28682.1 - 7.5e-47 158.7 0.0 3.1e-46 156.7 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 CAR28682.1 - 2.8e-19 69.2 1.4 9.5e-19 67.5 1.4 2.0 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.20 CAR28682.1 - 2.8e-17 63.0 0.2 9.2e-17 61.4 0.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 CAR28682.1 - 4.2e-07 29.5 5.7 8.5e-07 28.5 0.2 2.7 2 0 0 2 2 2 1 GGA N-GAT domain HSA PF07529.13 CAR28683.1 - 7.8e-15 55.0 0.0 7.8e-15 55.0 0.0 4.0 3 1 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 CAR28683.1 - 1.9e-10 40.8 0.8 6.9e-10 39.0 0.8 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CAR28683.1 - 0.00057 20.0 0.0 0.0025 17.9 0.0 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Serinc PF03348.15 CAR28683.1 - 0.67 8.8 8.9 1.2 7.9 8.9 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) BCIP PF13862.6 CAR28684.1 - 9e-47 159.5 0.1 1.2e-46 159.1 0.1 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein SET PF00856.28 CAR28685.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 SET domain EMP24_GP25L PF01105.24 CAR28686.1 - 5.1e-39 134.1 0.1 6e-39 133.9 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ThiF PF00899.21 CAR28687.1 - 2.8e-61 207.0 0.0 3.9e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CAR28687.1 - 7.3e-12 45.8 0.0 1.6e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 CAR28687.1 - 0.0025 17.9 0.0 0.0058 16.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Mto2_bdg PF12808.7 CAR28687.1 - 0.031 14.6 0.4 0.067 13.5 0.4 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region APC_N_CC PF16689.5 CAR28687.1 - 0.86 9.7 3.7 2 8.5 0.5 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF1652 PF07865.11 CAR28688.1 - 0.072 12.9 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) DUF349 PF03993.12 CAR28688.1 - 0.43 10.9 2.6 1.3 9.4 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) AT_hook PF02178.19 CAR28688.1 - 5.4 7.2 12.6 0.12 12.4 5.7 2.0 2 0 0 2 2 2 0 AT hook motif Cys_Met_Meta_PP PF01053.20 CAR28689.1 - 8.2e-66 222.1 0.0 2.4e-65 220.6 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CAR28689.1 - 6.6e-05 22.0 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CAR28689.1 - 0.016 14.4 0.0 0.021 14.0 0.0 1.3 1 1 0 1 1 1 0 Aminotransferase class I and II Peptidase_M18 PF02127.15 CAR28690.1 - 3.8e-179 596.0 0.0 4.3e-179 595.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CAR28690.1 - 9.9e-09 34.6 0.0 2.1e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Rad60-SLD PF11976.8 CAR28691.1 - 3.1e-23 81.4 2.8 4.3e-22 77.7 3.5 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like HIM1 PF08732.10 CAR28691.1 - 0.034 13.7 0.6 0.06 12.9 0.6 1.4 1 0 0 1 1 1 0 HIM1 RNA_pol_Rpb1_5 PF04998.17 CAR28692.1 - 4.8e-82 275.4 0.2 6.7e-82 274.9 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CAR28692.1 - 8.8e-81 271.6 0.0 1.5e-80 270.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CAR28692.1 - 2.5e-75 252.3 0.1 7.4e-75 250.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CAR28692.1 - 2.4e-38 131.5 0.0 6.1e-38 130.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CAR28692.1 - 2.1e-30 104.8 0.0 5e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DSS1_SEM1 PF05160.13 CAR28693.1 - 6.1e-21 74.2 19.6 7.1e-21 74.0 19.6 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.29 CAR28694.1 - 4.5e-41 140.4 0.1 1.1e-40 139.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CAR28694.1 - 9.8e-20 70.3 0.1 1.9e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CAR28694.1 - 1.3e-08 34.5 0.0 3e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CAR28694.1 - 2.8e-05 24.1 0.6 0.00013 21.9 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAR28694.1 - 6.7e-05 23.1 0.0 0.00024 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CAR28694.1 - 7.9e-05 23.1 0.1 0.019 15.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAR28694.1 - 0.00064 20.0 0.3 0.072 13.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CAR28694.1 - 0.00074 19.3 0.1 0.0018 18.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CAR28694.1 - 0.0093 16.1 0.0 0.025 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 CAR28694.1 - 0.0099 15.3 0.1 0.05 13.1 0.1 2.0 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 CAR28694.1 - 0.015 14.7 0.1 0.04 13.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 CAR28694.1 - 0.021 14.6 0.1 0.23 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CAR28694.1 - 0.022 13.9 0.0 0.046 12.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CAR28694.1 - 0.024 14.3 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 CAR28694.1 - 0.048 13.2 0.0 0.099 12.1 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 CAR28694.1 - 0.051 12.9 0.3 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 CAR28694.1 - 0.11 12.2 1.2 0.27 10.9 0.1 2.3 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CAR28694.1 - 0.15 12.4 0.0 0.57 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA helicase TolA_bind_tri PF16331.5 CAR28694.1 - 2.4 8.3 6.7 3.6 7.7 4.4 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation WD40 PF00400.32 CAR28695.1 - 4e-28 97.1 9.8 3.6e-07 30.8 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR28695.1 - 2.8e-10 40.3 0.0 0.045 14.1 0.0 4.4 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR28695.1 - 0.0037 17.2 0.2 2.3 8.1 0.0 3.3 1 1 4 5 5 5 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR28695.1 - 0.064 12.2 0.0 0.47 9.4 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 CAR28695.1 - 0.21 9.9 0.0 20 3.3 0.0 2.8 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz NUC153 PF08159.12 CAR28696.1 - 2e-13 49.9 1.3 2e-13 49.9 1.3 3.1 3 0 0 3 3 3 2 NUC153 domain AP3D1 PF06375.11 CAR28696.1 - 0.00019 21.7 11.6 0.00019 21.7 11.6 6.0 4 1 3 7 7 7 1 AP-3 complex subunit delta-1 FYVE_2 PF02318.16 CAR28696.1 - 1.6 8.9 8.6 5 7.4 8.6 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger TLD PF07534.16 CAR28697.1 - 4e-24 85.4 0.0 8.9e-22 77.8 0.0 2.3 2 0 0 2 2 2 2 TLD RIO1 PF01163.22 CAR28698.1 - 5.7e-70 234.8 0.6 5.7e-70 234.8 0.6 2.1 2 0 0 2 2 2 1 RIO1 family Nop14 PF04147.12 CAR28698.1 - 0.15 10.2 26.9 0.2 9.9 26.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CAR28698.1 - 0.47 8.7 27.2 0.83 7.9 27.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 CAR28698.1 - 0.65 9.1 19.2 1.2 8.3 19.2 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 CAR28698.1 - 1.3 7.0 25.0 2.2 6.2 25.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi Kei1 PF08552.11 CAR28699.1 - 1.6e-36 125.9 16.5 1e-30 107.0 9.3 2.0 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 Aldo_ket_red PF00248.21 CAR28700.1 - 1.9e-47 161.9 0.0 1.6e-45 155.6 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family FHA PF00498.26 CAR28701.1 - 7.6e-05 23.0 0.1 0.0002 21.7 0.1 1.7 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 CAR28701.1 - 0.052 13.8 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 FHA domain Bac_surface_Ag PF01103.23 CAR28702.1 - 6.1e-22 78.5 5.8 7.6e-22 78.2 5.0 1.5 1 1 0 1 1 1 1 Surface antigen RAI1 PF08652.11 CAR28703.1 - 0.033 14.4 0.1 0.099 12.8 0.0 1.8 1 1 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease YCII PF03795.14 CAR28704.1 - 0.00025 21.4 0.0 0.0003 21.2 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Profilin PF00235.19 CAR28705.1 - 1.4e-45 154.7 0.0 1.5e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Profilin Leo1 PF04004.13 CAR28706.1 - 1.1e-46 158.7 0.0 1.1e-46 158.7 0.0 3.8 4 1 1 5 5 5 1 Leo1-like protein 2CSK_N PF08521.10 CAR28706.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal BUD22 PF09073.10 CAR28706.1 - 0.43 9.9 39.1 0.088 12.1 15.9 2.2 2 0 0 2 2 2 0 BUD22 Glyco_hydro_18 PF00704.28 CAR28707.1 - 2.7e-73 247.4 0.3 3.4e-73 247.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GPP34 PF05719.11 CAR28708.1 - 1.4e-66 224.5 0.0 1.7e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Asp PF00026.23 CAR28709.1 - 6.3e-68 229.5 13.2 4.8e-60 203.6 1.5 2.5 3 0 0 3 3 3 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR28709.1 - 1.4e-10 41.7 1.3 0.0003 21.1 0.0 3.0 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CAR28709.1 - 0.0011 19.5 1.1 13 6.5 0.0 4.1 4 0 0 4 4 4 2 Aspartyl protease Asp PF00026.23 CAR28710.1 - 8.4e-72 242.2 3.5 8.4e-72 242.2 3.5 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR28710.1 - 1.8e-10 41.3 2.6 1.8e-10 41.3 2.6 2.8 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CAR28710.1 - 0.057 14.1 2.0 15 6.3 0.1 3.5 2 2 1 3 3 3 0 Aspartyl protease TAXi_C PF14541.6 CAR28710.1 - 0.071 12.9 0.0 0.79 9.5 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 CAR28710.1 - 0.081 13.5 0.0 45 4.7 0.0 3.4 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease SPX PF03105.19 CAR28710.1 - 0.11 12.4 10.9 0.025 14.5 6.9 1.7 2 0 0 2 2 2 0 SPX domain Asp PF00026.23 CAR28711.1 - 8.1e-74 248.9 1.2 3.5e-73 246.8 1.2 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR28711.1 - 1.2e-09 38.7 1.5 1e-08 35.6 1.5 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CAR28711.1 - 0.0029 18.2 0.2 9.1 7.0 0.0 3.7 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 CAR28711.1 - 0.0048 17.4 0.0 15 6.3 0.0 3.4 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp PF00026.23 CAR28712.1 - 5.5e-65 219.9 0.9 2.9e-64 217.5 0.9 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR28712.1 - 1.5e-10 41.6 1.2 6.8e-09 36.2 1.2 3.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CAR28712.1 - 0.00021 21.9 0.1 6.1 7.6 0.0 4.0 3 1 1 4 4 4 2 Aspartyl protease gag-asp_proteas PF13975.6 CAR28712.1 - 0.0011 19.4 0.0 4.8 7.8 0.0 3.7 4 1 0 4 4 4 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CAR28712.1 - 0.041 13.6 0.1 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Yqai PF09466.10 CAR28712.1 - 3.8 7.9 4.9 2.1 8.7 0.0 2.5 3 0 0 3 3 3 0 Hypothetical protein Yqai Asp PF00026.23 CAR28713.1 - 6.9e-74 249.1 2.4 1e-73 248.5 2.4 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR28713.1 - 3.7e-16 59.9 3.5 2.5e-15 57.1 1.5 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CAR28713.1 - 0.019 15.6 0.3 46 4.8 0.0 3.6 3 0 0 3 3 3 0 Aspartyl protease ANAPC2 PF08672.11 CAR28714.1 - 3.1e-21 75.6 0.6 1.3e-18 67.2 0.1 3.3 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 CAR28714.1 - 8.6e-07 28.0 0.0 3e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Cullin family EAP30 PF04157.16 CAR28714.1 - 0.027 13.8 0.0 0.059 12.6 0.0 1.6 1 0 0 1 1 1 0 EAP30/Vps36 family AAA_lid_8 PF17868.1 CAR28714.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain RPA_C PF08784.11 CAR28714.1 - 0.16 12.7 0.0 0.52 11.0 0.0 1.9 2 0 0 2 2 2 0 Replication protein A C terminal Cullin_binding PF03556.15 CAR28715.1 - 6e-29 100.9 5.9 1.1e-28 100.1 5.9 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 CAR28715.1 - 5.5e-14 51.7 0.6 1.1e-13 50.8 0.6 1.5 1 0 0 1 1 1 1 UBA-like domain TFIID_20kDa PF03847.13 CAR28716.1 - 5.6e-32 110.1 1.9 6.5e-32 109.8 0.3 2.0 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CAR28716.1 - 0.098 13.0 0.1 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone WD40 PF00400.32 CAR28717.1 - 5.8e-51 169.3 29.0 3.5e-05 24.5 0.0 11.6 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.12 CAR28717.1 - 1.6e-20 73.4 0.9 2.9e-20 72.6 0.9 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CAR28717.1 - 1.4e-19 70.2 5.6 0.00063 20.0 0.0 8.3 3 3 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAR28717.1 - 5.6e-10 39.0 6.5 0.0004 19.8 0.1 4.4 4 1 1 5 5 5 2 WD40-like domain Nup160 PF11715.8 CAR28717.1 - 4.4e-07 28.9 7.5 0.15 10.7 0.1 5.5 4 2 0 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CAR28717.1 - 3.1e-05 23.1 2.6 5.6 5.8 0.0 6.4 2 2 4 8 8 8 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 CAR28717.1 - 0.00035 20.4 1.0 2.5 7.8 0.0 4.4 4 0 0 4 4 4 2 TUP1-like enhancer of split Nucleoporin_N PF08801.11 CAR28717.1 - 0.00067 18.5 9.3 3.7 6.2 0.1 5.5 2 2 4 6 6 6 2 Nup133 N terminal like Frtz PF11768.8 CAR28717.1 - 0.00094 17.6 0.1 0.43 8.8 0.0 3.3 2 1 2 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz ELYS-bb PF16687.5 CAR28717.1 - 0.021 13.4 0.1 0.068 11.8 0.0 1.9 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin CBM_2 PF00553.19 CAR28717.1 - 0.11 12.9 0.3 0.66 10.3 0.0 2.5 3 0 0 3 3 2 0 Cellulose binding domain zf-C2H2 PF00096.26 CAR28718.1 - 2.3e-09 37.2 21.1 0.00057 20.2 2.3 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR28718.1 - 0.00011 22.7 13.9 0.18 12.7 1.2 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR28718.1 - 0.033 14.6 0.1 0.033 14.6 0.1 4.9 5 0 0 5 5 5 0 Zinc-finger double domain HVSL PF09749.9 CAR28719.1 - 1.2e-22 80.6 0.5 2.2e-22 79.7 0.5 1.5 1 1 0 1 1 1 1 Uncharacterised conserved protein DUF881 PF05949.12 CAR28719.1 - 0.063 13.2 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) Choline_kinase PF01633.20 CAR28720.1 - 2.8e-67 226.4 0.0 4e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 CAR28720.1 - 5.6e-11 42.0 0.0 1.7e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.23 CAR28720.1 - 3.2e-06 27.2 0.0 0.0076 16.2 0.0 2.5 2 1 0 2 2 2 2 Phosphotransferase enzyme family DUF3984 PF13136.6 CAR28720.1 - 0.022 14.2 4.6 0.038 13.4 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) 2-oxoacid_dh PF00198.23 CAR28721.1 - 1.2e-78 263.7 0.0 1.6e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CAR28721.1 - 2.9e-16 59.1 1.0 5e-16 58.3 1.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 CAR28721.1 - 9e-05 23.1 0.4 0.011 16.4 0.1 2.5 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 CAR28721.1 - 0.00018 21.2 0.4 0.0016 18.2 0.1 2.2 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 CAR28721.1 - 0.00057 19.8 0.3 0.0013 18.6 0.3 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 CAR28721.1 - 0.017 15.1 0.4 0.26 11.3 0.0 2.3 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 CAR28721.1 - 0.18 11.0 1.7 0.52 9.5 0.7 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion CCDC53 PF10152.9 CAR28721.1 - 0.32 11.4 5.3 0.61 10.5 5.3 1.6 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Slx4 PF09494.10 CAR28722.1 - 4.8e-15 55.3 0.0 8.5e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 Slx4 endonuclease Mcp5_PH PF12814.7 CAR28723.1 - 1.5e-39 134.9 0.1 4.8e-39 133.2 0.1 2.0 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology ADIP PF11559.8 CAR28723.1 - 2.1e-05 24.7 9.7 2.1e-05 24.7 9.7 5.5 2 1 1 4 4 4 1 Afadin- and alpha -actinin-Binding PH PF00169.29 CAR28723.1 - 0.00016 22.1 0.5 0.0022 18.5 0.0 2.7 2 0 0 2 2 2 1 PH domain Hint_2 PF13403.6 CAR28723.1 - 0.0065 16.8 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 Hint domain PH_2 PF08458.10 CAR28723.1 - 0.012 16.0 0.0 0.082 13.3 0.0 2.6 1 0 0 1 1 1 0 Plant pleckstrin homology-like region LEM PF03020.15 CAR28723.1 - 0.22 11.1 0.0 0.22 11.1 0.0 4.2 5 0 0 5 5 5 0 LEM domain HNH_repeat PF18780.1 CAR28723.1 - 1.3 8.9 3.5 70 3.4 0.0 4.7 5 0 0 5 5 5 0 Homing endonuclease repeat zf-CCCH PF00642.24 CAR28724.1 - 3.3e-17 61.9 17.4 1.9e-09 37.2 3.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CAR28724.1 - 1.8e-07 31.0 20.2 2e-05 24.5 4.1 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CAR28724.1 - 2.3e-06 27.3 15.9 1.2e-05 25.0 1.6 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CAR28724.1 - 0.0083 16.8 10.8 0.026 15.2 1.2 2.6 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 CAR28724.1 - 0.086 13.3 15.0 0.34 11.4 1.0 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Defensin_int PF17858.1 CAR28724.1 - 1.1 9.2 3.9 0.48 10.5 0.6 1.9 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide Arginase PF00491.21 CAR28726.1 - 5.2e-74 249.2 0.0 6.1e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family PEX11 PF05648.14 CAR28727.1 - 3.5e-07 29.9 1.7 9e-07 28.6 1.7 1.6 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) 2-Hacid_dh_C PF02826.19 CAR28728.1 - 1.7e-34 118.7 0.0 2.6e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TFIIA PF03153.13 CAR28729.1 - 3.5e-44 152.5 21.1 1.6e-23 84.4 14.1 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Fungal_TACC PF12709.7 CAR28730.1 - 1.9e-31 108.3 11.9 1.9e-31 108.3 11.9 8.4 2 1 4 8 8 7 1 Fungal Transforming acidic coiled-coil (TACC) proteins TPR_MLP1_2 PF07926.12 CAR28730.1 - 0.00019 21.5 14.3 0.00019 21.5 14.3 5.9 3 2 3 6 6 6 3 TPR/MLP1/MLP2-like protein Syntaxin_2 PF14523.6 CAR28730.1 - 0.0024 18.2 1.7 0.0024 18.2 1.7 7.3 3 2 4 8 8 8 1 Syntaxin-like protein ATG16 PF08614.11 CAR28730.1 - 0.0027 18.0 8.6 0.0027 18.0 8.6 6.2 2 1 3 6 6 6 2 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 CAR28730.1 - 0.085 12.7 59.4 0.1 12.4 3.5 7.3 1 1 4 7 7 7 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 CAR28730.1 - 0.14 12.6 29.9 2.2 8.8 0.1 7.3 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 CAR28730.1 - 0.19 11.1 53.5 0.17 11.2 2.9 4.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Filament PF00038.21 CAR28730.1 - 0.21 11.2 83.8 2.3 7.7 12.9 4.8 1 1 0 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 CAR28730.1 - 0.26 10.1 82.9 0.049 12.5 15.8 5.5 1 1 4 5 5 5 0 Spc7 kinetochore protein DASH_Dad1 PF08649.10 CAR28730.1 - 0.45 10.8 0.1 0.45 10.8 0.1 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad1 ApoO PF09769.9 CAR28730.1 - 0.63 10.0 24.5 4.9 7.1 3.0 5.9 2 1 2 5 5 5 0 Apolipoprotein O FUSC PF04632.12 CAR28730.1 - 1.4 7.4 21.7 1.6 7.2 9.8 3.2 1 1 2 3 3 3 0 Fusaric acid resistance protein family rve_3 PF13683.6 CAR28730.1 - 2.9 7.7 11.0 1.3 8.9 0.2 4.7 4 1 2 6 6 6 0 Integrase core domain RhoGAP PF00620.27 CAR28731.1 - 5.3e-38 130.2 0.2 1.4e-37 128.8 0.2 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 CAR28731.1 - 1.6e-07 31.8 0.0 4.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 PH domain PX PF00787.24 CAR28731.1 - 2.4e-07 30.7 1.5 6.1e-07 29.4 1.5 1.7 1 0 0 1 1 1 1 PX domain DUF1708 PF08101.11 CAR28731.1 - 0.00028 20.2 0.0 0.00028 20.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) Cnn_1N PF07989.11 CAR28731.1 - 0.067 13.4 2.9 0.13 12.4 1.4 2.3 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 PRKG1_interact PF15898.5 CAR28731.1 - 8.3 7.4 8.7 3.1 8.7 5.0 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain PikAIV_N PF18605.1 CAR28731.1 - 9.9 5.8 6.8 1.6 8.4 2.6 1.9 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain LIAS_N PF16881.5 CAR28732.1 - 4.1e-25 88.3 1.0 1.3e-24 86.7 0.3 2.1 2 1 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CAR28732.1 - 1.6e-12 48.1 0.0 3e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Ivy PF08816.11 CAR28732.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Inhibitor of vertebrate lysozyme (Ivy) Spore_GerAC PF05504.11 CAR28732.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Hist_deacetyl PF00850.19 CAR28733.1 - 4.9e-53 180.6 0.1 7.6e-53 180.0 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain DFF40 PF09230.10 CAR28733.1 - 0.039 13.6 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 DNA fragmentation factor 40 kDa Peptidase_C14 PF00656.22 CAR28734.1 - 2.9e-64 217.4 0.0 3.7e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Baculo_PEP_C PF04513.12 CAR28735.1 - 0.00057 19.9 26.3 1.1 9.3 3.4 5.0 2 1 3 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 CAR28735.1 - 0.00082 18.1 13.9 0.00082 18.1 13.9 4.0 2 1 1 3 3 3 2 Flagellar Assembly Protein A Apolipoprotein PF01442.18 CAR28735.1 - 0.018 14.9 43.9 0.15 12.0 9.6 3.5 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain Muted PF14942.6 CAR28735.1 - 1.8 8.9 49.3 0.33 11.3 12.1 4.1 3 1 1 4 4 4 0 Organelle biogenesis, Muted-like protein GAS PF13851.6 CAR28735.1 - 5.1 6.4 63.4 1.2 8.4 10.3 4.0 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding NUDIX PF00293.28 CAR28736.1 - 5.7e-28 97.6 0.0 8.4e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SpoU_methylase PF00588.19 CAR28737.1 - 2.3e-25 89.4 0.0 7.7e-25 87.7 0.0 1.8 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CAR28737.1 - 1.9e-16 60.1 0.0 3.6e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding IGPD PF00475.18 CAR28738.1 - 1.1e-60 204.1 0.3 1.6e-60 203.6 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Mit_ribos_Mrp51 PF11709.8 CAR28739.1 - 1.5e-69 235.4 1.8 1.6e-68 232.0 1.8 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit DEAD PF00270.29 CAR28740.1 - 1.8e-47 161.4 0.0 5.7e-47 159.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR28740.1 - 1e-32 112.8 0.0 2.1e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR28740.1 - 0.0029 17.6 0.0 0.0081 16.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CAR28740.1 - 0.088 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CAR28740.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ribonuc_red_lgC PF02867.15 CAR28741.1 - 9.3e-178 592.0 0.0 1.2e-177 591.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CAR28741.1 - 2.5e-24 85.1 0.0 5.6e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain APG6 PF04111.12 CAR28742.1 - 5.9e-62 208.8 0.1 1.1e-61 207.9 0.1 1.4 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CAR28742.1 - 3e-28 99.0 22.4 5.9e-28 98.0 22.4 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region YabA PF06156.13 CAR28742.1 - 0.0095 16.6 7.0 0.029 15.0 7.0 1.8 1 0 0 1 1 1 1 Initiation control protein YabA FapA PF03961.13 CAR28742.1 - 3.4 6.2 7.8 5.7 5.4 7.8 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A MMR_HSR1 PF01926.23 CAR28743.1 - 1.2e-07 31.7 0.2 1.7e-06 28.0 0.1 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR28743.1 - 0.0036 17.2 0.1 0.0088 16.0 0.1 1.7 1 1 0 1 1 1 1 RsgA GTPase Roc PF08477.13 CAR28743.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CAR28743.1 - 0.055 13.5 0.1 0.53 10.3 0.1 2.2 1 1 1 2 2 2 0 Dynamin family RNA_helicase PF00910.22 CAR28743.1 - 0.06 13.7 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase FeoB_N PF02421.18 CAR28743.1 - 0.08 12.5 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 CAR28743.1 - 0.12 12.7 0.0 0.53 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CAR28743.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Noc2 PF03715.13 CAR28744.1 - 2.5e-128 427.5 5.1 2.5e-128 427.5 5.1 2.0 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 CAR28744.1 - 0.00022 19.6 0.1 0.00022 19.6 0.1 3.6 3 1 0 3 3 3 1 Nop14-like family DUF4048 PF13257.6 CAR28744.1 - 0.055 13.3 14.5 0.16 11.8 14.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) XPC-binding PF09280.11 CAR28744.1 - 0.055 13.2 0.0 9.7 6.0 0.0 3.0 2 0 0 2 2 2 0 XPC-binding domain Mei5 PF10376.9 CAR28745.1 - 2.3e-33 115.8 18.6 2.6e-33 115.6 18.6 1.0 1 0 0 1 1 1 1 Double-strand recombination repair protein CAMSAP_CC1 PF17095.5 CAR28745.1 - 0.0086 15.9 0.4 0.0086 15.9 0.4 2.4 3 0 0 3 3 3 1 Spectrin-binding region of Ca2+-Calmodulin Vac_Fusion PF02346.16 CAR28745.1 - 2 8.1 5.4 26 4.5 0.1 3.7 3 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 RNA_pol_Rpb2_6 PF00562.28 CAR28746.1 - 1.2e-123 413.1 0.1 1.2e-123 413.1 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CAR28746.1 - 1.8e-60 204.0 2.2 2e-60 203.8 1.4 1.5 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CAR28746.1 - 3e-41 141.2 4.1 9.3e-41 139.5 2.4 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CAR28746.1 - 1.5e-33 115.1 0.3 5.5e-33 113.2 0.3 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CAR28746.1 - 4.4e-27 94.1 0.1 1.6e-26 92.4 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CAR28746.1 - 1.8e-18 66.5 0.0 4.4e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CAR28746.1 - 4.9e-11 43.0 0.8 2e-10 41.1 0.8 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Tfb2 PF03849.14 CAR28747.1 - 2e-139 464.5 2.6 2.5e-139 464.2 2.6 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CAR28747.1 - 2.4e-20 72.7 0.3 5.6e-20 71.5 0.3 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CAR28747.1 - 8.9e-05 22.6 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAS PF00989.25 CAR28747.1 - 0.069 13.2 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 PAS fold Coatomer_WDAD PF04053.14 CAR28748.1 - 1.1e-131 440.0 1.3 1.7e-131 439.3 1.3 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CAR28748.1 - 5.8e-84 282.2 0.0 8.4e-84 281.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CAR28748.1 - 6.6e-39 131.2 16.3 4.2e-08 33.7 0.1 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR28748.1 - 1e-10 41.8 0.1 7e-05 23.1 0.0 5.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR28748.1 - 1.7e-05 24.8 0.5 0.58 10.0 0.0 3.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CAR28748.1 - 2.4e-05 23.2 8.0 0.098 11.3 0.1 4.0 2 1 1 4 4 4 3 Nucleoporin Nup120/160 ENTH PF01417.20 CAR28748.1 - 0.0047 17.0 0.1 0.014 15.4 0.1 1.8 1 0 0 1 1 1 1 ENTH domain LisH PF08513.11 CAR28748.1 - 0.045 13.7 0.1 0.27 11.3 0.0 2.2 2 0 0 2 2 2 0 LisH TPR_1 PF00515.28 CAR28748.1 - 0.15 11.9 0.1 0.67 9.9 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Tubulin PF00091.25 CAR28750.1 - 4.1e-67 226.2 0.0 1.2e-66 224.7 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CAR28750.1 - 6.4e-23 81.3 0.0 1.4e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CAR28750.1 - 1.3e-07 31.9 0.0 2.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CAR28750.1 - 0.0083 15.3 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin like PGM_PMM_II PF02879.16 CAR28750.1 - 0.096 13.3 0.0 13 6.5 0.0 2.5 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF2013 PF09431.10 CAR28751.1 - 5.4e-39 133.5 13.8 5.4e-39 133.5 13.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) MIT PF04212.18 CAR28752.1 - 0.051 13.7 0.4 0.14 12.2 0.1 2.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Spectrin PF00435.21 CAR28752.1 - 0.35 11.4 5.3 1.1 9.7 1.8 2.7 2 1 0 2 2 2 0 Spectrin repeat PCI PF01399.27 CAR28753.1 - 2e-19 70.0 1.8 3.4e-19 69.3 0.0 2.4 3 0 0 3 3 3 1 PCI domain RPN5_C PF18098.1 CAR28753.1 - 1.6e-15 56.9 4.5 6.1e-15 55.0 4.5 2.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF4864 PF16156.5 CAR28753.1 - 0.016 15.9 0.2 0.17 12.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4864) OEP PF02321.18 CAR28753.1 - 0.04 13.7 3.2 0.1 12.4 3.2 1.7 1 0 0 1 1 1 0 Outer membrane efflux protein Nop14 PF04147.12 CAR28754.1 - 1.7e-180 602.3 68.6 3.4e-99 333.3 7.5 2.1 1 1 1 2 2 2 2 Nop14-like family APG9 PF04109.16 CAR28755.1 - 4.8e-194 645.8 17.9 5.8e-194 645.6 17.9 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 RNA_pol_Rpc4 PF05132.14 CAR28756.1 - 1e-24 87.7 1.2 1e-24 87.7 1.2 4.2 3 2 1 4 4 4 1 RNA polymerase III RPC4 T3SS_needle_E PF08988.10 CAR28756.1 - 0.12 12.5 0.8 0.23 11.6 0.8 1.4 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle NEMO PF11577.8 CAR28756.1 - 0.46 10.5 5.2 0.15 12.1 1.7 1.9 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO DUF3713 PF12506.8 CAR28756.1 - 1.4 9.2 5.6 13 6.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) NOA36 PF06524.12 CAR28756.1 - 2.6 7.3 7.1 6 6.1 7.1 1.6 1 0 0 1 1 1 0 NOA36 protein Sas10 PF09368.10 CAR28757.1 - 9.6e-30 102.9 8.7 9.6e-30 102.9 8.7 2.6 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CAR28757.1 - 7.5e-05 23.3 0.5 7.5e-05 23.3 0.5 3.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Peroxin-13_N PF04088.13 CAR28757.1 - 0.12 12.6 0.1 0.12 12.6 0.1 3.1 3 2 0 3 3 3 0 Peroxin 13, N-terminal region MutS_V PF00488.21 CAR28758.1 - 5.2e-47 160.3 0.1 1.3e-46 159.0 0.1 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAR28758.1 - 1.3e-17 64.7 1.9 1.3e-17 64.7 1.9 2.0 2 1 0 2 2 2 1 MutS domain III Spt20 PF12090.8 CAR28758.1 - 0.26 10.9 2.1 2.1 7.9 0.0 2.6 3 0 0 3 3 3 0 Spt20 family Cyclin_N PF00134.23 CAR28759.1 - 1.3e-45 154.3 0.2 2.6e-45 153.3 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAR28759.1 - 1.1e-33 115.8 0.0 1.1e-33 115.8 0.0 2.5 3 0 0 3 3 3 1 Cyclin, C-terminal domain DUF3245 PF11595.8 CAR28759.1 - 0.074 13.5 6.9 0.19 12.2 6.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Sigma70_ner PF04546.13 CAR28759.1 - 0.093 12.6 10.3 0.21 11.5 10.3 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 CAR28759.1 - 0.23 11.5 13.9 0.041 13.9 9.8 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 CAR28759.1 - 0.46 8.5 18.6 0.68 8.0 18.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 CAR28759.1 - 0.47 9.7 14.1 0.84 8.9 14.1 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 CAR28759.1 - 0.77 10.2 18.1 2 8.8 18.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIA PF03153.13 CAR28759.1 - 1.7 8.6 22.0 2.5 8.0 22.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Prothymosin PF03247.14 CAR28759.1 - 2.2 8.8 20.8 0.11 13.0 15.2 1.7 2 0 0 2 2 2 0 Prothymosin/parathymosin family PPP4R2 PF09184.11 CAR28759.1 - 9.5 5.7 18.8 15 5.1 18.8 1.3 1 0 0 1 1 1 0 PPP4R2 WD40 PF00400.32 CAR28760.1 - 5.8e-09 36.4 2.7 0.036 14.9 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR28760.1 - 0.00062 20.0 0.0 1.1 9.6 0.0 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CAR28760.1 - 0.044 12.1 0.0 3.2 5.9 0.0 2.2 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF4536 PF15055.6 CAR28761.1 - 0.072 13.3 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) Pkinase PF00069.25 CAR28762.1 - 5.5e-68 229.2 0.0 8.1e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28762.1 - 1.8e-38 132.3 0.0 2.7e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR28762.1 - 0.00025 20.5 0.0 0.00045 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAR28762.1 - 0.00035 19.5 0.0 0.00072 18.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CAR28762.1 - 0.0017 17.4 0.3 0.0017 17.4 0.3 2.2 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CAR28762.1 - 0.23 11.3 0.5 0.39 10.6 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family DEAD PF00270.29 CAR28763.1 - 9.6e-45 152.5 0.1 1.6e-44 151.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR28763.1 - 3.2e-29 101.5 1.5 1.3e-28 99.5 0.4 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Phage_integrase PF00589.22 CAR28763.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 Phage integrase family Terminase_3 PF04466.13 CAR28763.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Phage terminase large subunit PNP_UDP_1 PF01048.20 CAR28764.1 - 1.6e-44 151.9 0.0 2.6e-44 151.2 0.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.32 CAR28765.1 - 5.6e-21 74.5 17.6 3.6e-05 24.4 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR28765.1 - 8.7e-06 26.0 6.1 0.4 11.0 0.1 4.8 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 CAR28765.1 - 0.021 14.7 4.5 0.12 12.3 4.5 2.3 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Sel1 PF08238.12 CAR28766.1 - 1e-21 76.9 4.8 6.3e-05 23.5 0.0 7.7 8 0 0 8 8 8 4 Sel1 repeat TPR_12 PF13424.6 CAR28766.1 - 0.0023 18.2 1.6 0.53 10.6 0.1 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR28766.1 - 0.0034 17.8 0.2 0.64 10.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAR28766.1 - 0.031 13.9 0.0 0.12 12.1 0.0 2.1 1 0 0 1 1 1 0 TPR repeat TPR_16 PF13432.6 CAR28766.1 - 0.032 14.9 0.9 4.5 8.0 0.0 3.9 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAR28766.1 - 0.18 12.5 4.1 65 4.5 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 CAR28766.1 - 0.25 11.5 7.4 4.6 7.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAR28766.1 - 8.8 6.3 16.8 1.6 8.7 0.1 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat CENP-X PF09415.10 CAR28767.1 - 6.4e-25 87.3 0.5 8e-25 87.0 0.5 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X DHquinase_II PF01220.19 CAR28767.1 - 0.011 15.4 0.2 0.015 15.0 0.2 1.1 1 0 0 1 1 1 0 Dehydroquinase class II CBFD_NFYB_HMF PF00808.23 CAR28767.1 - 0.042 14.1 0.1 0.068 13.5 0.1 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ENTH PF01417.20 CAR28768.1 - 2.3e-40 137.5 0.0 4.9e-40 136.4 0.0 1.6 1 0 0 1 1 1 1 ENTH domain HDV_ag PF01517.18 CAR28768.1 - 0.039 13.7 0.6 0.039 13.7 0.6 2.2 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen L31 PF09784.9 CAR28768.1 - 7.5 7.0 8.4 0.78 10.2 1.3 2.5 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 DNA_ligase_A_M PF01068.21 CAR28769.1 - 1.3e-61 207.8 0.0 2.2e-61 207.1 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CAR28769.1 - 1.9e-47 161.8 0.2 3.6e-46 157.7 0.0 2.4 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CAR28769.1 - 1.8e-25 89.4 0.0 4.8e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CAR28769.1 - 0.00077 19.8 0.0 0.0023 18.2 0.0 1.9 2 0 0 2 2 2 1 RNA ligase Phasin PF05597.11 CAR28769.1 - 0.08 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DNA_ligase_OB_2 PF14743.6 CAR28769.1 - 0.19 11.8 0.5 12 6.0 0.1 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain Heme_oxygenase PF01126.20 CAR28770.1 - 7.2e-13 48.8 1.2 3.6e-12 46.5 1.2 2.2 1 1 0 1 1 1 1 Heme oxygenase PT-VENN PF04829.13 CAR28770.1 - 0.17 12.0 1.6 0.17 12.0 0.4 1.6 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif DUF1980 PF09323.10 CAR28770.1 - 1 9.2 3.9 3.1 7.7 0.1 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1980) zf-Mss51 PF13824.6 CAR28771.1 - 1.4e-17 63.6 0.7 3.1e-17 62.4 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.11 CAR28771.1 - 0.0037 17.0 0.0 0.0085 15.8 0.0 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain NOT2_3_5 PF04153.18 CAR28772.1 - 1.6e-30 105.9 1.7 2e-30 105.5 1.7 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family AAA_18 PF13238.6 CAR28773.1 - 5e-32 111.2 0.4 1.2e-31 109.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CAR28773.1 - 2.1e-06 28.2 0.0 7.8e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CAR28773.1 - 7.5e-05 22.5 0.1 0.17 11.6 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase RNA_helicase PF00910.22 CAR28773.1 - 0.00014 22.2 0.2 0.00084 19.7 0.0 2.0 2 0 0 2 2 2 1 RNA helicase KTI12 PF08433.10 CAR28773.1 - 0.0002 20.9 0.0 0.00058 19.4 0.0 1.7 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.6 CAR28773.1 - 0.00066 20.0 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAR28773.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAR28773.1 - 0.0011 19.3 0.0 0.0023 18.3 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 CAR28773.1 - 0.0013 18.7 0.0 1 9.2 0.1 2.2 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_33 PF13671.6 CAR28773.1 - 0.0044 17.2 0.1 0.072 13.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CAR28773.1 - 0.0057 15.9 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.18 CAR28773.1 - 0.0067 15.8 1.3 0.011 15.1 0.2 1.9 2 1 1 3 3 3 1 FtsK/SpoIIIE family ADK PF00406.22 CAR28773.1 - 0.0091 16.1 0.0 3.2 7.8 0.0 2.3 2 0 0 2 2 2 1 Adenylate kinase AAA_22 PF13401.6 CAR28773.1 - 0.0091 16.3 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CAR28773.1 - 0.0098 15.6 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain T4_Rnl2_C PF18043.1 CAR28773.1 - 0.014 15.5 0.3 0.034 14.3 0.3 1.6 1 0 0 1 1 1 0 T4 RNA ligase 2 C-terminal Sigma54_activ_2 PF14532.6 CAR28773.1 - 0.031 14.4 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 CAR28773.1 - 0.037 13.9 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 CAR28773.1 - 0.057 13.9 2.7 0.74 10.3 2.7 2.1 1 1 0 1 1 1 0 ABC transporter MeaB PF03308.16 CAR28773.1 - 0.062 12.3 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 CAR28773.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase IMPa_N_2 PF18650.1 CAR28773.1 - 0.1 11.9 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 Immunomodulating metalloprotease N-terminal domain Mg_chelatase PF01078.21 CAR28773.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CAR28773.1 - 0.15 12.4 0.0 0.4 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain PG_binding_1 PF01471.18 CAR28773.1 - 0.17 12.1 0.0 3.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Putative peptidoglycan binding domain zf-RanBP PF00641.18 CAR28774.1 - 5.4e-22 76.8 9.6 9e-11 40.9 0.6 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CAR28774.1 - 4.6e-08 32.8 0.0 0.00096 18.9 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rubredoxin PF00301.20 CAR28774.1 - 0.32 11.1 7.2 1.2 9.2 0.7 2.7 2 0 0 2 2 2 0 Rubredoxin DZR PF12773.7 CAR28774.1 - 1 9.4 8.2 11 6.2 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-MIZ PF02891.20 CAR28774.1 - 3.8 7.3 5.6 21 5.0 0.4 2.9 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger ADH_N PF08240.12 CAR28775.1 - 3.3e-26 91.3 3.0 3.3e-26 91.3 3.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR28775.1 - 1.1e-21 77.2 0.5 1.1e-21 77.2 0.5 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CAR28775.1 - 1.5e-06 27.9 0.3 1e-05 25.2 0.3 2.1 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 CAR28775.1 - 6.3e-06 26.5 0.2 1.1e-05 25.6 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 CAR28775.1 - 7.1e-05 22.2 0.7 0.00013 21.3 0.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CAR28775.1 - 0.0019 17.6 0.2 0.0031 16.9 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CAR28775.1 - 0.0044 16.6 0.1 0.0074 15.9 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 CAR28775.1 - 0.009 17.1 0.0 0.018 16.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 CAR28775.1 - 0.0093 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain PALP PF00291.25 CAR28775.1 - 0.012 15.0 0.3 0.019 14.4 0.3 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme 3HCDH_N PF02737.18 CAR28775.1 - 0.045 13.6 0.2 0.078 12.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2249 PF10006.9 CAR28775.1 - 0.063 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Pyr_redox PF00070.27 CAR28775.1 - 0.12 13.0 0.3 1.1 9.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase COQ9 PF08511.11 CAR28776.1 - 3.4e-24 84.4 0.1 6.3e-24 83.5 0.1 1.5 1 0 0 1 1 1 1 COQ9 Prefoldin_2 PF01920.20 CAR28777.1 - 8.6e-24 83.5 8.1 9.7e-24 83.4 8.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4201 PF13870.6 CAR28777.1 - 0.048 13.4 4.6 0.43 10.3 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) YgaB PF14182.6 CAR28777.1 - 0.054 13.9 3.1 0.22 11.9 0.3 2.2 2 0 0 2 2 2 0 YgaB-like protein DUF1192 PF06698.11 CAR28777.1 - 0.073 13.1 2.4 0.08 13.0 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) APG6_N PF17675.1 CAR28777.1 - 0.087 13.4 6.6 0.18 12.3 6.6 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Spc24 PF08286.11 CAR28777.1 - 0.094 13.0 6.5 0.99 9.7 0.4 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.15 CAR28777.1 - 0.16 11.7 9.3 0.16 11.8 0.6 2.5 2 1 0 2 2 2 0 Septum formation initiator Bcr-Abl_Oligo PF09036.10 CAR28777.1 - 0.61 10.1 3.8 0.66 10.0 0.5 2.1 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain UPF0242 PF06785.11 CAR28777.1 - 1 9.4 7.2 1.9 8.5 7.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus POC1 PF10450.9 CAR28778.1 - 3.2e-88 295.3 0.0 3.5e-88 295.1 0.0 1.0 1 0 0 1 1 1 1 POC1 chaperone Nop PF01798.18 CAR28779.1 - 9.7e-84 280.4 0.1 9.7e-84 280.4 0.1 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CAR28779.1 - 1.7e-20 73.1 0.3 1.7e-20 73.1 0.3 2.6 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GAGA_bind PF06217.12 CAR28779.1 - 0.19 12.0 21.5 0.33 11.2 21.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2052 PF09747.9 CAR28779.1 - 0.54 10.3 26.7 0.8 9.8 26.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 CAR28779.1 - 0.57 10.0 33.6 0.87 9.4 33.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.8 CAR28779.1 - 1.4 7.7 37.1 2.4 7.0 37.1 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RRN3 PF05327.11 CAR28779.1 - 8.4 4.8 14.9 13 4.2 14.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFR_dimer PF04253.15 CAR28780.1 - 1.1e-32 112.7 0.2 2.6e-32 111.5 0.2 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CAR28780.1 - 0.00022 21.0 0.0 0.00034 20.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PIGA PF08288.12 CAR28781.1 - 1e-40 138.2 2.0 3.3e-40 136.6 2.0 1.9 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CAR28781.1 - 1.7e-32 112.7 1.4 2.6e-32 112.2 0.5 1.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CAR28781.1 - 2.8e-30 105.1 0.0 4.4e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CAR28781.1 - 1.1e-25 90.6 0.0 2.3e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CAR28781.1 - 1.5e-13 51.5 0.0 2.3e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CAR28781.1 - 1.1e-06 28.7 0.2 2.6e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CAR28781.1 - 0.0023 18.3 0.0 0.0046 17.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CAR28781.1 - 0.16 11.6 0.5 1.8 8.2 0.0 2.3 1 1 0 2 2 2 0 Starch synthase catalytic domain CAP_GLY PF01302.25 CAR28782.1 - 1.5e-21 76.1 1.1 2.5e-21 75.5 1.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain HALZ PF02183.18 CAR28782.1 - 0.0018 18.4 24.8 2.7 8.3 0.0 6.5 6 1 1 7 7 7 3 Homeobox associated leucine zipper Shugoshin_N PF07558.11 CAR28782.1 - 0.06 13.2 11.6 0.17 11.7 1.1 4.8 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region DUF3698 PF12479.8 CAR28782.1 - 0.4 11.2 6.9 0.25 11.9 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3698) CSN5_C PF18323.1 CAR28782.1 - 0.85 10.6 6.9 2.6 9.0 0.3 3.4 2 1 1 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain FAM76 PF16046.5 CAR28782.1 - 3.5 6.9 20.0 0.032 13.6 5.8 2.4 2 0 0 2 2 2 0 FAM76 protein APC_N_CC PF16689.5 CAR28782.1 - 7 6.8 17.5 1.7 8.8 0.3 4.7 4 1 0 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain EF-hand_7 PF13499.6 CAR28783.1 - 6.8e-27 93.7 11.3 3e-15 56.4 2.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CAR28783.1 - 1.9e-25 86.5 15.3 3e-08 32.6 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CAR28783.1 - 1.7e-21 74.3 12.2 2.1e-07 30.3 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 CAR28783.1 - 2.6e-18 65.6 12.0 2.1e-10 40.3 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 CAR28783.1 - 3.3e-13 48.5 10.3 0.00011 21.5 1.5 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 CAR28783.1 - 1.9e-08 34.5 1.5 0.0016 18.7 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CAR28783.1 - 6.9e-08 32.4 2.6 0.0012 18.8 0.1 2.5 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CAR28783.1 - 0.00027 21.3 1.6 0.15 12.4 0.1 2.2 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 CAR28783.1 - 0.024 14.6 1.3 1.1 9.1 0.0 3.2 1 1 3 4 4 4 0 Caleosin related protein HTH_40 PF14493.6 CAR28783.1 - 0.041 14.3 0.3 0.27 11.7 0.1 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain PhetRS_B1 PF18262.1 CAR28783.1 - 0.062 13.5 0.9 0.16 12.2 0.4 1.9 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain EF-hand_14 PF17959.1 CAR28783.1 - 0.064 13.6 0.6 0.67 10.3 0.2 2.2 2 0 0 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 CAR28783.1 - 0.064 13.5 0.3 6.8 7.0 0.1 2.4 2 0 0 2 2 2 0 Dockerin type I domain SUB1_ProdP9 PF18213.1 CAR28783.1 - 0.066 13.1 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 PsbU PF06514.11 CAR28783.1 - 0.073 13.1 0.1 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) SurA_N_2 PF13623.6 CAR28783.1 - 0.12 12.3 0.4 1.8 8.4 0.1 2.5 2 1 1 3 3 3 0 SurA N-terminal domain EF-hand_11 PF08976.11 CAR28783.1 - 0.2 12.5 0.4 0.53 11.2 0.1 1.9 2 1 0 2 2 2 0 EF-hand domain VCBS PF13517.6 CAR28783.1 - 0.49 11.0 5.2 1 10.0 0.0 2.6 3 0 0 3 3 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella KOW PF00467.29 CAR28784.1 - 0.016 15.2 0.4 0.036 14.0 0.4 1.6 1 0 0 1 1 1 0 KOW motif DUF2001 PF09393.10 CAR28784.1 - 0.19 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein HIT PF01230.23 CAR28785.1 - 3e-20 72.8 0.6 7.7e-20 71.5 0.1 1.8 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 CAR28785.1 - 1.3e-18 67.6 0.6 3.4e-18 66.2 0.6 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 CAR28785.1 - 2.5e-15 56.6 3.0 6.4e-15 55.4 3.0 1.7 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 CAR28785.1 - 0.001 19.0 0.3 0.0025 17.8 0.3 1.6 1 0 0 1 1 1 1 BED zinc finger TBCA PF02970.16 CAR28785.1 - 0.03 14.6 0.6 0.12 12.7 0.4 1.8 2 0 0 2 2 2 0 Tubulin binding cofactor A zf-C2H2_4 PF13894.6 CAR28785.1 - 0.2 12.6 0.7 0.2 12.6 0.7 2.4 2 1 1 3 3 3 0 C2H2-type zinc finger AAA PF00004.29 CAR28786.1 - 9.9e-43 145.7 0.0 2e-42 144.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR28786.1 - 1.7e-08 34.2 0.0 3.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CAR28786.1 - 8.2e-08 32.8 1.9 2.4e-05 24.8 0.1 3.2 2 2 2 4 4 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 CAR28786.1 - 1.5e-07 31.2 0.5 3.6e-07 30.0 0.5 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CAR28786.1 - 2.1e-06 27.8 0.1 5.7e-05 23.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAR28786.1 - 1.7e-05 25.0 0.5 4.6e-05 23.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CAR28786.1 - 4e-05 23.4 0.0 8.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CAR28786.1 - 0.00016 21.6 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CAR28786.1 - 0.0017 18.7 0.2 0.026 14.8 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 CAR28786.1 - 0.0018 18.7 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 CAR28786.1 - 0.0054 16.9 0.1 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CAR28786.1 - 0.0061 15.8 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 CAR28786.1 - 0.0063 15.9 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CAR28786.1 - 0.0077 16.8 1.6 0.035 14.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CAR28786.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CAR28786.1 - 0.012 15.3 0.0 0.037 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Spectrin PF00435.21 CAR28786.1 - 0.019 15.4 2.1 1.1 9.8 3.1 2.6 2 1 0 2 2 2 0 Spectrin repeat AAA_28 PF13521.6 CAR28786.1 - 0.022 15.0 0.1 0.069 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CAR28786.1 - 0.036 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CAR28786.1 - 0.044 13.1 2.3 0.06 12.7 0.1 2.3 3 0 0 3 3 3 0 KaiC AAA_7 PF12775.7 CAR28786.1 - 0.046 13.2 0.0 0.15 11.6 0.1 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 CAR28786.1 - 0.047 13.1 0.2 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 PhoH-like protein Fib_alpha PF08702.10 CAR28786.1 - 0.049 13.8 6.7 0.11 12.6 6.7 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Sigma54_activat PF00158.26 CAR28786.1 - 0.057 13.1 0.2 0.21 11.3 0.0 1.9 2 1 0 2 2 2 0 Sigma-54 interaction domain Prot_ATP_OB_N PF17758.1 CAR28786.1 - 0.059 13.0 0.3 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 CAR28786.1 - 0.068 12.7 0.2 0.23 11.0 0.2 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 CAR28786.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CAR28786.1 - 0.17 11.8 0.1 0.44 10.4 0.1 1.9 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 CAR28786.1 - 0.19 11.5 10.1 0.85 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Apc15p PF05841.11 CAR28786.1 - 1.1 10.0 13.2 2.3 9.0 13.2 1.5 1 0 0 1 1 1 0 Apc15p protein Trypan_PARP PF05887.11 CAR28786.1 - 2.1 8.3 5.7 3.8 7.5 5.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HABP4_PAI-RBP1 PF04774.15 CAR28786.1 - 2.4 9.0 13.1 4.2 8.3 13.1 1.3 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Hexapep PF00132.24 CAR28787.1 - 2.4e-06 27.1 9.4 0.037 13.8 0.3 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CAR28787.1 - 4.8e-05 23.8 0.0 8.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 CAR28787.1 - 0.0051 15.8 0.3 0.013 14.4 0.3 1.7 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 CAR28787.1 - 0.083 11.0 0.5 0.12 10.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 CAR28787.1 - 0.13 11.8 0.0 0.32 10.6 0.0 1.7 1 1 0 1 1 1 0 Nucleotidyl transferase Hexapep_2 PF14602.6 CAR28787.1 - 0.9 9.3 10.6 2.9 7.7 1.3 3.4 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase UbiA PF01040.18 CAR28788.1 - 3.9e-48 164.0 14.1 3.9e-48 164.0 14.1 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family MitMem_reg PF13012.6 CAR28789.1 - 7.3e-33 113.3 0.8 1.5e-32 112.3 0.8 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CAR28789.1 - 1.6e-29 102.3 0.0 3.8e-29 101.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RNA_pol_Rpb1_1 PF04997.12 CAR28789.1 - 0.41 9.9 5.8 0.28 10.5 3.7 1.7 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 1 ATP_bind_1 PF03029.17 CAR28790.1 - 1.1e-81 274.1 0.0 1.1e-81 274.1 0.0 1.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 CAR28790.1 - 0.0008 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 CAR28790.1 - 0.0086 16.1 0.0 0.02 14.9 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CAR28790.1 - 0.024 14.5 0.0 12 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 CAR28790.1 - 0.03 14.7 2.7 0.54 10.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CAR28790.1 - 0.037 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CAR28790.1 - 0.049 14.2 0.1 0.32 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 CAR28790.1 - 0.13 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 CAR28790.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CAR28790.1 - 0.16 12.4 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TBCA PF02970.16 CAR28792.1 - 1.3e-25 89.6 9.1 1.4e-25 89.4 9.1 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A Cytochrom_C_2 PF01322.20 CAR28792.1 - 0.0054 17.6 0.5 0.006 17.5 0.5 1.0 1 0 0 1 1 1 1 Cytochrome C' DUF2046 PF09755.9 CAR28792.1 - 0.064 12.5 6.2 0.086 12.1 6.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Fzo_mitofusin PF04799.13 CAR28792.1 - 0.18 11.4 3.1 0.23 11.0 3.1 1.2 1 0 0 1 1 1 0 fzo-like conserved region Pkinase PF00069.25 CAR28794.1 - 1.5e-46 158.9 0.0 9.4e-45 153.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28794.1 - 3.2e-19 69.2 0.0 6.9e-19 68.1 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase CDC45 PF02724.14 CAR28794.1 - 8.5e-05 21.0 7.4 0.00012 20.5 7.4 1.2 1 0 0 1 1 1 1 CDC45-like protein Kinase-like PF14531.6 CAR28794.1 - 0.035 13.4 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Paz_1 PF18349.1 CAR28794.1 - 0.039 13.9 0.1 0.084 12.8 0.1 1.5 1 0 0 1 1 1 0 PAZ domain Oxidored_FMN PF00724.20 CAR28795.1 - 5.3e-115 384.3 0.0 6.1e-115 384.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TFIID-31kDa PF02291.15 CAR28796.1 - 6.2e-49 165.1 0.1 7.3e-49 164.9 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit ChAPs PF09295.10 CAR28797.1 - 2.9e-168 560.0 0.1 3.6e-168 559.7 0.1 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 CAR28797.1 - 9.5e-06 25.4 0.4 0.044 13.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAR28797.1 - 0.0018 18.8 0.2 18 6.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAR28797.1 - 0.0026 18.4 0.1 65 4.7 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAR28797.1 - 0.004 16.9 0.0 2.4 8.2 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR28797.1 - 0.013 15.6 0.0 0.4 11.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR28797.1 - 0.024 14.8 0.4 8.4 6.7 0.0 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CAR28797.1 - 0.044 13.9 0.1 11 6.2 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAR28797.1 - 0.055 13.5 0.2 17 5.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 CAR28797.1 - 0.068 13.6 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAR28797.1 - 0.07 13.4 0.2 4 7.8 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3445 PF11927.8 CAR28797.1 - 0.1 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3445) TPR_19 PF14559.6 CAR28797.1 - 0.16 12.5 0.1 2.3 8.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAR28797.1 - 0.78 10.4 6.3 5.3 7.8 0.1 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_76 PF03663.14 CAR28798.1 - 4e-157 523.4 12.1 4.8e-157 523.2 12.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RGS PF00615.19 CAR28799.1 - 7.9e-05 22.9 1.4 0.00017 21.9 0.5 1.9 2 1 0 2 2 2 1 Regulator of G protein signaling domain Leader_CPA1 PF08252.11 CAR28800.1 - 1.4e-15 56.4 2.6 1.4e-15 56.3 2.6 1.0 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide GATase PF00117.28 CAR28801.1 - 1.6e-47 161.8 0.0 2.2e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 CAR28801.1 - 2e-43 147.3 0.0 4.3e-43 146.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 CAR28801.1 - 2.3e-06 27.5 0.3 0.00044 20.1 0.1 3.0 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 CAR28801.1 - 0.024 14.5 0.0 0.053 13.3 0.0 1.5 1 1 0 1 1 1 0 DJ-1/PfpI family RCC1 PF00415.18 CAR28802.1 - 1.4e-21 76.9 1.8 2.1e-07 31.5 0.0 5.2 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAR28802.1 - 1.8e-15 56.3 14.2 5.2e-09 35.7 0.2 5.4 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CAR28802.1 - 6.3e-08 32.8 1.1 3.8e-06 27.1 0.1 3.3 2 2 1 3 3 3 1 BTB/POZ domain SNF2_N PF00176.23 CAR28803.1 - 2.7e-76 256.6 1.0 5.7e-76 255.5 1.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CAR28803.1 - 1.3e-36 125.1 4.6 1.3e-36 125.1 4.6 3.1 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 CAR28803.1 - 7.2e-36 123.3 14.0 7.2e-36 123.3 14.0 3.9 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 CAR28803.1 - 7.8e-21 74.5 0.0 5.4e-19 68.6 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR28803.1 - 3e-11 43.6 0.0 3e-11 43.6 0.0 3.6 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR28803.1 - 3.4e-06 26.9 0.0 1.3e-05 25.0 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1878 PF08963.10 CAR28803.1 - 0.074 13.6 1.3 0.43 11.1 0.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1878) RNase_3_N PF18497.1 CAR28804.1 - 5.2e-43 145.6 2.0 1.1e-42 144.5 2.0 1.6 1 0 0 1 1 1 1 Ribonuclease III N-terminal domain Ribonuclease_3 PF00636.26 CAR28804.1 - 1.4e-18 67.4 2.0 3.2e-18 66.3 0.0 2.5 3 1 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CAR28804.1 - 5.7e-15 55.6 0.0 1.3e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 CAR28804.1 - 1.4e-06 28.9 0.0 5.8e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif RelE PF06296.12 CAR28804.1 - 0.032 14.4 0.1 0.082 13.0 0.1 1.7 2 0 0 2 2 2 0 RelE toxin of RelE / RelB toxin-antitoxin system Amidohydro_1 PF01979.20 CAR28805.1 - 1.7e-19 70.3 0.0 2.6e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CAR28805.1 - 2.9e-09 36.9 0.0 1.9e-05 24.4 0.2 2.5 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.20 CAR28805.1 - 0.01 16.2 0.1 0.037 14.4 0.1 2.0 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain NTP_transf_2 PF01909.23 CAR28805.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF382 PF04037.13 CAR28806.1 - 5e-54 181.8 0.6 5e-54 181.8 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 CAR28806.1 - 1.1e-22 79.6 3.1 2e-22 78.7 3.1 1.5 1 0 0 1 1 1 1 PSP LRRFIP PF09738.9 CAR28807.1 - 0.024 14.2 3.8 0.028 13.9 3.8 1.0 1 0 0 1 1 1 0 LRRFIP family DUF1796 PF08795.10 CAR28807.1 - 0.033 14.2 0.1 0.035 14.1 0.1 1.0 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) DUF2034 PF10356.9 CAR28808.1 - 2.3e-55 186.9 0.0 2.8e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) DUF4533 PF15047.6 CAR28808.1 - 0.0048 16.5 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4533) Mrr_cat PF04471.12 CAR28808.1 - 0.032 14.3 0.0 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease Mito_carr PF00153.27 CAR28809.1 - 6.3e-28 96.5 5.6 7.7e-12 45.0 0.0 3.5 2 1 0 3 3 3 3 Mitochondrial carrier protein TPT PF03151.16 CAR28810.1 - 1.2e-35 123.2 13.4 1.7e-34 119.5 13.4 2.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CAR28810.1 - 5.2e-05 23.4 23.0 0.0043 17.2 3.8 3.7 4 0 0 4 4 4 3 EamA-like transporter family SART-1 PF03343.13 CAR28811.1 - 9.5e-36 123.6 49.8 2.2e-13 49.7 0.5 5.0 1 1 3 4 4 4 4 SART-1 family Glyco_transf_64 PF09258.10 CAR28811.1 - 0.091 12.0 0.9 0.23 10.7 0.4 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain Nop PF01798.18 CAR28812.1 - 7.8e-81 270.9 0.2 7.8e-81 270.9 0.2 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CAR28812.1 - 1.4e-19 70.2 1.4 1.4e-19 70.2 1.4 2.5 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DUF4604 PF15377.6 CAR28812.1 - 0.0085 16.5 43.9 0.017 15.5 43.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.12 CAR28812.1 - 0.92 9.3 32.8 2 8.2 32.8 1.6 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CTP_transf_1 PF01148.20 CAR28813.1 - 0.0044 16.8 6.3 0.006 16.4 6.1 1.4 1 1 0 1 1 1 1 Cytidylyltransferase family Ribosomal_L18A PF01775.17 CAR28814.1 - 2.2e-53 179.5 1.0 3.6e-53 178.8 1.0 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A DUF1057 PF06342.12 CAR28814.1 - 0.052 12.6 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Apolipoprotein PF01442.18 CAR28815.1 - 0.025 14.4 1.5 2 8.3 0.1 2.4 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 CAR28815.1 - 0.25 11.4 4.3 0.62 10.1 0.2 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cation_efflux PF01545.21 CAR28816.1 - 4.3e-55 186.5 0.8 6.1e-55 186.0 0.8 1.2 1 0 0 1 1 1 1 Cation efflux family DUF2809 PF10990.8 CAR28816.1 - 0.15 12.7 1.2 21 5.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2809) YwcE PF17368.2 CAR28816.1 - 7.1 7.4 6.5 48 4.7 0.5 2.7 2 0 0 2 2 2 0 Spore morphogenesis and germination YwcE SUN PF03856.13 CAR28817.1 - 5.6e-83 278.2 20.4 6.5e-83 277.9 20.4 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Bac_rhodopsin PF01036.18 CAR28818.1 - 1.2e-74 250.6 22.4 1.4e-74 250.4 22.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Orf78 PF06024.12 CAR28818.1 - 0.064 13.6 0.3 8.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Orf78 (ac78) DUF4131 PF13567.6 CAR28818.1 - 0.76 9.4 12.7 1.8 8.2 3.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) COX6B PF02297.17 CAR28819.1 - 8.6e-23 80.4 6.3 1.1e-22 80.1 6.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.11 CAR28819.1 - 0.036 14.2 0.3 0.048 13.8 0.3 1.2 1 0 0 1 1 1 0 Prolamin-like Sigma70_ECF PF07638.11 CAR28819.1 - 0.045 13.6 0.1 0.054 13.4 0.1 1.1 1 0 0 1 1 1 0 ECF sigma factor Pet191_N PF10203.9 CAR28819.1 - 0.085 13.2 3.1 0.53 10.6 2.9 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 AMP-binding PF00501.28 CAR28820.1 - 3.4e-83 279.6 0.0 5e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAR28820.1 - 0.0043 18.0 0.0 0.01 16.8 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 CAR28821.1 - 3.6e-25 87.6 0.1 5.4e-14 51.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR28821.1 - 0.001 18.7 0.2 0.021 14.5 0.1 2.1 1 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR28821.1 - 0.0037 17.4 0.1 3 8.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif Limkain-b1 PF11608.8 CAR28821.1 - 0.044 13.8 0.1 8.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 CTNNBL PF08216.11 CAR28821.1 - 0.053 13.7 0.2 0.24 11.6 0.1 2.1 2 0 0 2 2 2 0 Catenin-beta-like, Arm-motif containing nuclear Glyco_transf_8 PF01501.20 CAR28822.1 - 0.14 11.7 5.5 0.1 12.1 1.5 2.5 3 0 0 3 3 3 0 Glycosyl transferase family 8 zf-RING_2 PF13639.6 CAR28823.1 - 3.5e-07 30.4 7.7 3.5e-07 30.4 7.7 2.3 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 CAR28823.1 - 1.4e-05 25.2 3.9 1.4e-05 25.2 3.9 2.0 2 0 0 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.7 CAR28823.1 - 7.9e-05 22.9 6.9 0.00019 21.6 6.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAR28823.1 - 0.0008 19.4 1.2 0.0018 18.3 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 CAR28823.1 - 0.0083 16.2 5.8 0.025 14.7 5.8 1.9 1 0 0 1 1 1 1 RING-variant domain TAN PF11640.8 CAR28823.1 - 0.062 13.4 0.2 0.062 13.4 0.2 4.1 5 0 0 5 5 4 0 Telomere-length maintenance and DNA damage repair Zn_ribbon_17 PF17120.5 CAR28823.1 - 0.072 12.7 5.8 0.21 11.3 3.7 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CAR28823.1 - 0.38 10.6 11.6 0.066 13.1 7.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR28823.1 - 0.67 9.9 13.6 0.072 13.0 8.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CAR28823.1 - 1.8 8.5 9.0 1.9 8.4 3.9 2.7 2 1 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CAR28823.1 - 2.2 8.3 5.4 4.8 7.1 5.4 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 CAR28823.1 - 2.5 8.5 13.4 0.083 13.2 7.0 1.9 2 0 0 2 2 2 0 RING-like domain zf-RING_4 PF14570.6 CAR28823.1 - 6.9 6.5 7.3 1.7e+02 2.1 7.1 2.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CAR28823.1 - 8.6 6.3 6.6 6.2 6.8 0.4 2.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SAM_decarbox PF01536.16 CAR28824.1 - 8.6e-132 439.4 4.0 9.9e-132 439.2 4.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Pyridoxal_deC PF00282.19 CAR28825.1 - 2e-54 184.8 0.0 2.9e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Ala_racemase_N PF01168.20 CAR28827.1 - 5.7e-20 71.9 0.0 7.1e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.20 CAR28828.1 - 1.8e-105 353.5 9.3 2.2e-105 353.2 9.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CAR28828.1 - 1.7e-05 25.0 0.0 6.2e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 CAR28828.1 - 0.0082 16.4 0.1 0.028 14.7 0.1 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain Sybindin PF04099.12 CAR28828.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Sybindin-like family DNA_pol3_delta2 PF13177.6 CAR28829.1 - 2e-11 43.9 0.2 1.2e-10 41.4 0.1 2.2 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 CAR28829.1 - 1.3e-07 32.1 0.1 6.5e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 CAR28829.1 - 3.4e-05 23.7 0.1 0.00026 20.8 0.3 2.1 2 0 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CAR28829.1 - 0.00013 22.3 0.1 0.00054 20.3 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_16 PF13191.6 CAR28829.1 - 0.00057 20.3 0.1 0.0024 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 CAR28829.1 - 0.0011 18.9 0.0 0.002 18.1 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 CAR28829.1 - 0.0012 19.1 0.6 0.023 15.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CAR28829.1 - 0.002 18.4 0.6 0.0057 17.0 0.0 2.1 3 0 0 3 3 3 1 AAA C-terminal domain NAD_binding_6 PF08030.12 CAR28829.1 - 0.036 14.2 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain AAA_27 PF13514.6 CAR28829.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CAR28829.1 - 0.16 11.7 0.1 0.56 9.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CAR28829.1 - 0.33 11.0 1.7 1 9.4 0.3 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Ribosomal_L16 PF00252.18 CAR28830.1 - 1.6e-35 122.0 0.2 2.5e-35 121.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Peptidase_M20 PF01546.28 CAR28831.1 - 2.7e-35 122.0 0.0 4.5e-35 121.2 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR28831.1 - 2.2e-14 53.3 0.1 4.6e-14 52.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CAR28831.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Cnd2 PF05786.14 CAR28832.1 - 1.8e-137 460.1 34.2 2.1e-111 374.0 26.1 2.5 2 1 0 2 2 2 2 Condensin complex subunit 2 CNDH2_N PF06278.11 CAR28832.1 - 4.7e-05 23.6 0.2 4.7e-05 23.6 0.2 3.2 3 0 0 3 3 3 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal FAD_binding_3 PF01494.19 CAR28833.1 - 4e-20 72.4 0.0 9.1e-20 71.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 CAR28833.1 - 0.00079 18.6 0.1 0.0065 15.5 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 CAR28833.1 - 0.0023 18.5 0.0 0.013 16.1 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CAR28833.1 - 0.0027 16.8 0.0 0.0046 16.1 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CAR28833.1 - 0.003 16.8 0.0 0.034 13.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAR28833.1 - 0.0052 17.0 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CAR28833.1 - 0.016 14.3 0.1 0.027 13.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 CAR28833.1 - 0.042 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 CAR28833.1 - 0.1 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 CAR28833.1 - 0.14 11.8 0.0 0.38 10.3 0.1 1.6 1 1 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CAR28833.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_M41 PF01434.18 CAR28834.1 - 1.4e-58 197.9 0.1 1.4e-58 197.9 0.1 1.7 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.29 CAR28834.1 - 2.2e-40 138.1 2.4 6e-40 136.7 0.0 2.6 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR28834.1 - 1.1e-08 34.7 0.0 2.9e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CAR28834.1 - 1.5e-05 25.4 0.2 0.00012 22.5 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR28834.1 - 0.00041 20.6 0.2 0.16 12.3 0.1 3.1 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 CAR28834.1 - 0.00059 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CAR28834.1 - 0.0013 18.5 0.0 0.0088 15.8 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ATP-synt_E PF05680.12 CAR28834.1 - 0.0022 18.3 2.5 0.015 15.6 3.0 2.1 2 0 0 2 2 2 1 ATP synthase E chain PhoH PF02562.16 CAR28834.1 - 0.0027 17.2 0.4 0.47 9.9 0.2 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_5 PF07728.14 CAR28834.1 - 0.0049 16.9 0.1 0.017 15.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CAR28834.1 - 0.022 14.9 0.1 0.18 12.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CAR28834.1 - 0.026 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 CAR28834.1 - 0.03 14.4 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CAR28834.1 - 0.037 13.4 0.0 0.094 12.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AP-5_subunit_s1 PF15001.6 CAR28834.1 - 0.047 13.7 3.2 0.11 12.5 3.2 1.5 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 AAA_18 PF13238.6 CAR28834.1 - 0.058 13.9 3.0 0.34 11.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 CAR28834.1 - 0.079 12.5 0.8 0.97 9.0 0.4 2.3 1 1 0 2 2 2 0 AAA domain TsaE PF02367.17 CAR28834.1 - 0.099 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CAR28834.1 - 0.11 12.2 0.7 1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 CAR28834.1 - 0.22 11.6 2.1 0.65 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_11 PF13086.6 CAR28834.1 - 0.64 9.7 6.3 5.8 6.6 0.2 2.7 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.6 CAR28834.1 - 0.98 9.6 0.0 0.98 9.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain Roughex PF06020.11 CAR28834.1 - 2.1 7.4 6.6 3.7 6.5 6.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Cyclin_C_2 PF16899.5 CAR28835.1 - 7e-31 106.7 0.2 4.5e-30 104.1 0.1 2.1 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 CAR28835.1 - 1.2e-11 44.5 0.3 2.1e-11 43.7 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 CAR28835.1 - 0.0037 17.3 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat ATP-synt_ab PF00006.25 CAR28836.1 - 1.3e-69 234.1 0.0 1.9e-69 233.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CAR28836.1 - 3.7e-47 159.8 0.4 6.9e-47 158.9 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CAR28836.1 - 8e-17 61.5 0.9 8e-17 61.5 0.9 2.2 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain Glyco_hydro_65m PF03632.15 CAR28837.1 - 8.3e-32 110.5 5.0 9.9e-31 106.9 0.2 2.6 2 1 1 3 3 3 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 CAR28837.1 - 8e-30 104.2 0.0 1.5e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 CAR28837.1 - 2.8e-05 23.9 0.3 0.0002 21.2 0.1 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain TB2_DP1_HVA22 PF03134.19 CAR28838.1 - 4.4e-26 90.6 7.6 7e-26 90.0 7.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Peptidase_M50B PF13398.6 CAR28838.1 - 0.078 12.6 6.5 0.07 12.8 5.3 1.5 1 1 1 2 2 2 0 Peptidase M50B-like DUF5056 PF16479.5 CAR28838.1 - 0.093 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) DUF2721 PF11026.8 CAR28838.1 - 0.18 11.7 1.3 0.44 10.4 0.0 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Adaptin_N PF01602.20 CAR28839.1 - 4.9e-104 348.8 20.9 8.2e-104 348.0 20.9 1.3 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CAR28839.1 - 4.6e-10 39.8 1.4 1.1e-09 38.5 1.4 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain DCB PF16213.5 CAR28839.1 - 0.027 14.1 0.3 0.14 11.8 0.1 2.4 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 Telomere_reg-2 PF10193.9 CAR28839.1 - 0.46 11.0 2.7 5.2 7.5 0.0 3.4 4 0 0 4 4 4 0 Telomere length regulation protein Arrestin_C PF02752.22 CAR28840.1 - 1.8e-08 34.9 1.1 1.8e-08 34.9 1.1 3.6 4 1 0 4 4 4 1 Arrestin (or S-antigen), C-terminal domain Mog1 PF04603.12 CAR28840.1 - 0.2 12.0 1.6 0.42 11.0 0.1 2.2 2 0 0 2 2 2 0 Ran-interacting Mog1 protein Got1 PF04178.12 CAR28841.1 - 1.8e-33 115.4 15.8 2.9e-33 114.7 15.8 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Terpene_synth_C PF03936.16 CAR28841.1 - 0.095 12.0 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain DUF2157 PF09925.9 CAR28841.1 - 0.63 9.8 5.6 0.87 9.4 5.2 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) DUF2207 PF09972.9 CAR28841.1 - 3.2 6.4 11.1 38 2.9 11.1 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) HLH PF00010.26 CAR28842.1 - 1.3e-12 47.5 0.8 2.9e-12 46.3 0.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Spt20 PF12090.8 CAR28842.1 - 0.00049 19.8 25.6 0.0011 18.6 16.9 2.4 2 0 0 2 2 2 2 Spt20 family DUF2722 PF10846.8 CAR28842.1 - 0.0029 16.6 24.1 0.014 14.4 16.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2722) ANAPC_CDC26 PF10471.9 CAR28842.1 - 0.0066 17.3 15.0 0.0066 17.3 15.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex APC subunit CDC26 DUF2347 PF09804.9 CAR28842.1 - 0.011 15.3 2.9 0.011 15.3 2.9 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) MecA PF05389.12 CAR28842.1 - 0.016 14.8 4.9 0.25 10.9 2.7 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Macoilin PF09726.9 CAR28842.1 - 0.039 12.5 12.4 0.052 12.1 12.4 1.1 1 0 0 1 1 1 0 Macoilin family Suf PF05843.14 CAR28842.1 - 0.083 12.9 11.7 0.054 13.5 6.7 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) RBM39linker PF15519.6 CAR28842.1 - 0.089 13.9 9.7 0.05 14.7 5.8 2.3 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF572 PF04502.13 CAR28842.1 - 0.12 12.0 8.0 0.038 13.6 4.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) CCDC53 PF10152.9 CAR28842.1 - 0.42 11.0 13.4 0.44 10.9 7.5 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Band_3_cyto PF07565.13 CAR28842.1 - 0.62 9.8 6.7 0.96 9.2 3.6 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Spb1_C PF07780.12 CAR28842.1 - 0.62 9.7 10.7 0.02 14.5 4.6 1.5 2 0 0 2 2 1 0 Spb1 C-terminal domain AAA_23 PF13476.6 CAR28842.1 - 0.63 10.5 17.3 0.14 12.6 13.1 1.9 2 0 0 2 2 2 0 AAA domain Neur_chan_memb PF02932.16 CAR28842.1 - 0.98 9.4 4.3 1 9.3 1.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FdhE PF04216.12 CAR28842.1 - 1.8 8.4 9.3 4.8 7.0 9.3 1.7 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation eIF-3_zeta PF05091.12 CAR28842.1 - 1.8 7.4 12.9 0.11 11.4 6.7 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1387 PF07139.11 CAR28842.1 - 2 8.0 13.5 0.59 9.8 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) Pex14_N PF04695.13 CAR28842.1 - 2.8 8.6 25.2 1 10.0 15.6 2.7 3 0 0 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5327 PF17261.2 CAR28842.1 - 4.9 8.0 20.1 1.2 9.9 12.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) WBP-1 PF11669.8 CAR28842.1 - 6.3 7.5 5.6 29 5.3 2.4 2.6 2 0 0 2 2 2 0 WW domain-binding protein 1 Baculo_PP31 PF05311.11 CAR28842.1 - 6.5 6.1 12.2 1.7 8.1 7.7 2.0 2 0 0 2 2 2 0 Baculovirus 33KDa late protein (PP31) DUF4834 PF16118.5 CAR28842.1 - 7 7.7 16.3 6.3 7.8 8.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4175 PF13779.6 CAR28842.1 - 7 4.4 25.0 0.86 7.4 18.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Mannosyl_trans3 PF11051.8 CAR28843.1 - 5.6e-72 242.4 0.0 1.2e-71 241.3 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative zf-HC5HC2H_2 PF13832.6 CAR28844.1 - 1.6e-31 108.7 11.5 2.2e-31 108.3 4.3 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CAR28844.1 - 4.5e-28 97.3 3.8 4.5e-28 97.3 3.8 3.5 2 1 1 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CAR28844.1 - 6.3e-14 51.2 4.2 6.3e-14 51.2 4.2 2.7 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.9 CAR28844.1 - 1.9e-12 47.9 0.6 3.8e-12 46.9 0.6 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD PF00628.29 CAR28844.1 - 2.7e-11 43.2 19.9 1.2e-10 41.1 4.7 3.0 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.22 CAR28844.1 - 0.01 15.7 0.3 0.01 15.7 0.3 2.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GCR PF02155.15 CAR28844.1 - 0.042 12.9 0.0 2 7.4 0.0 2.1 1 1 1 2 2 2 0 Glucocorticoid receptor Prok-RING_1 PF14446.6 CAR28844.1 - 0.15 12.0 16.3 0.037 14.0 4.4 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc_ribbon_16 PF17034.5 CAR28845.1 - 3.6e-26 91.8 15.1 6e-24 84.6 13.8 3.3 2 1 0 2 2 2 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 CAR28845.1 - 2.7e-06 26.9 7.9 2.7e-06 26.9 7.9 2.1 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CAR28845.1 - 0.25 12.3 1.0 65 4.6 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Pkinase PF00069.25 CAR28846.1 - 3.9e-60 203.4 0.0 3.9e-60 203.4 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR28846.1 - 3.6e-35 121.5 0.0 8.1e-35 120.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 CAR28846.1 - 1.4e-18 66.5 34.9 3e-11 43.0 14.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) HR1 PF02185.16 CAR28846.1 - 1.8e-17 63.2 16.9 6.5e-13 48.6 5.1 4.3 4 0 0 4 4 4 2 Hr1 repeat Pkinase_C PF00433.24 CAR28846.1 - 1.1e-10 42.0 3.4 5.4e-10 39.8 3.4 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 CAR28846.1 - 9.8e-06 25.8 0.1 2.3e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 C2 domain PHD_2 PF13831.6 CAR28846.1 - 8.1 6.1 16.2 1.8 8.2 3.6 2.7 2 0 0 2 2 2 0 PHD-finger Lgl_C PF08596.10 CAR28847.1 - 2.1e-128 428.4 0.0 3.9e-128 427.5 0.0 1.5 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 CAR28847.1 - 7.8e-07 29.3 0.0 0.8 10.0 0.0 5.4 5 1 1 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR28847.1 - 0.00064 20.5 3.3 0.05 14.5 0.1 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CAR28847.1 - 0.049 12.4 0.5 3.6 6.2 0.1 2.6 2 0 0 2 2 2 0 Nup133 N terminal like DUF5082 PF16888.5 CAR28847.1 - 0.58 10.4 3.2 0.25 11.6 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Cid2 PF09774.9 CAR28848.1 - 2.6e-38 132.0 1.6 3.1e-38 131.7 1.6 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DUF325 PF03804.13 CAR28848.1 - 0.084 12.9 0.5 6.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Viral proteins of unknown function IDO PF01231.18 CAR28849.1 - 1.3e-148 495.4 0.0 1.5e-148 495.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase tRNA-synt_His PF13393.6 CAR28850.1 - 8.5e-37 127.1 0.0 7e-36 124.1 0.0 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CAR28850.1 - 1.7e-15 57.0 0.0 3.1e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 CAR28850.1 - 0.067 12.3 0.0 0.31 10.1 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.7 CAR28850.1 - 0.092 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.20 CAR28850.1 - 0.098 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) HTH_24 PF13412.6 CAR28850.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding AIM24 PF01987.17 CAR28851.1 - 3.7e-38 131.4 0.0 5e-38 130.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 UNC-50 PF05216.13 CAR28852.1 - 1.2e-86 289.9 26.2 1.3e-86 289.7 26.2 1.0 1 0 0 1 1 1 1 UNC-50 family PLDc PF00614.22 CAR28854.1 - 1.1e-15 57.1 2.1 5.6e-08 32.6 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CAR28854.1 - 1.4e-11 44.4 0.1 5.9e-06 26.2 0.0 3.9 3 1 0 3 3 3 2 PLD-like domain PX PF00787.24 CAR28854.1 - 0.0063 16.5 0.3 0.0063 16.5 0.3 3.3 4 0 0 4 4 4 1 PX domain ANTH PF07651.16 CAR28855.1 - 7.7e-65 218.6 0.0 7.7e-65 218.6 0.0 2.2 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 CAR28855.1 - 2.2e-06 27.7 0.0 6e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 ENTH domain MPC PF03650.13 CAR28856.1 - 1.4e-45 153.9 0.1 1.7e-45 153.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers 4HBT_3 PF13622.6 CAR28857.1 - 7.6e-35 121.3 0.0 9.9e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CAR28857.1 - 1e-27 96.6 0.3 1.7e-20 73.2 0.1 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase DUF268 PF03269.14 CAR28858.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF268 ATP-grasp_2 PF08442.10 CAR28859.1 - 9.3e-72 240.8 0.4 1.5e-71 240.1 0.4 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CAR28859.1 - 6e-26 91.1 0.1 2.8e-25 88.9 0.1 2.2 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 CAR28859.1 - 0.0001 21.8 0.1 0.00026 20.5 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CAR28859.1 - 0.0011 18.7 0.0 0.0034 17.2 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Oxidored_FMN PF00724.20 CAR28860.1 - 3.4e-116 388.2 0.0 4.1e-116 388.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RWD PF05773.22 CAR28861.1 - 5.3e-23 81.5 0.9 5.3e-23 81.5 0.9 1.9 2 1 0 2 2 2 1 RWD domain DFRP_C PF16543.5 CAR28861.1 - 0.0002 21.8 3.7 0.0002 21.8 3.7 2.4 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 HDAC4_Gln PF12203.8 CAR28861.1 - 1.7 8.8 10.6 4.6 7.5 5.8 2.7 1 1 1 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 ENTH PF01417.20 CAR28862.1 - 5.2e-33 113.8 0.2 8.3e-33 113.1 0.2 1.3 1 0 0 1 1 1 1 ENTH domain PGA2 PF07543.12 CAR28862.1 - 0.016 15.2 7.3 0.016 15.2 7.3 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 Pro_isomerase PF00160.21 CAR28863.1 - 5.3e-46 156.8 0.0 5.9e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_polI_A14 PF08203.11 CAR28864.1 - 3.4e-20 72.5 0.6 6.7e-20 71.6 0.1 1.7 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Semialdhyde_dhC PF02774.18 CAR28865.1 - 4.3e-45 154.1 0.0 6.2e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CAR28865.1 - 4.1e-32 111.1 0.0 6.9e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CAR28865.1 - 0.01 16.1 0.0 0.02 15.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 CAR28865.1 - 0.022 15.5 0.0 0.049 14.4 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Methyltransf_16 PF10294.9 CAR28866.1 - 8.3e-07 28.9 0.1 0.0011 18.7 0.0 2.3 1 1 1 2 2 2 2 Lysine methyltransferase SAC3_GANP PF03399.16 CAR28867.1 - 2.5e-100 335.6 0.8 2.5e-100 335.6 0.8 2.2 2 0 0 2 2 2 1 SAC3/GANP family SAC3 PF12209.8 CAR28867.1 - 2.4e-21 75.7 1.7 1e-20 73.6 1.7 2.2 1 0 0 1 1 1 1 Leucine permease transcriptional regulator helical domain CSN8_PSD8_EIF3K PF10075.9 CAR28867.1 - 0.0087 16.0 1.1 0.086 12.8 0.2 2.6 2 1 0 2 2 2 1 CSN8/PSMD8/EIF3K family DUF4410 PF14366.6 CAR28867.1 - 4.6 7.2 8.7 0.68 9.8 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) Na_H_Exchanger PF00999.21 CAR28868.1 - 6.1e-88 295.2 21.7 7.3e-88 294.9 21.7 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 CAR28868.1 - 5.4e-63 213.8 61.4 1.1e-56 193.0 32.1 2.3 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus AA_permease PF00324.21 CAR28869.1 - 3.7e-80 269.8 42.2 2.5e-79 267.1 42.2 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR28869.1 - 8.4e-36 123.7 41.6 1.2e-34 119.9 41.6 2.0 1 1 0 1 1 1 1 Amino acid permease Cation_ATPase_C PF00689.21 CAR28869.1 - 0.3 10.8 17.0 0.28 10.9 0.5 2.8 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus TPR_17 PF13431.6 CAR28870.1 - 0.00012 22.3 0.3 0.027 14.8 0.6 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR28870.1 - 0.00021 21.2 5.5 0.57 10.5 0.5 4.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAR28870.1 - 0.00047 20.1 1.1 0.64 10.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAR28870.1 - 0.003 17.8 3.3 2.9 8.3 0.1 4.8 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CAR28870.1 - 0.0033 18.1 1.3 1.6 9.7 0.1 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR28870.1 - 0.0042 17.6 7.3 0.069 13.7 0.4 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TipAS PF07739.13 CAR28870.1 - 0.006 17.1 0.4 6.8 7.3 0.0 3.5 3 1 0 3 3 3 1 TipAS antibiotic-recognition domain aGPT-Pplase3 PF18746.1 CAR28870.1 - 0.0067 15.8 0.2 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 TPR_1 PF00515.28 CAR28870.1 - 0.015 15.1 1.6 24 5.0 0.7 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat aGPT-Pplase2 PF18724.1 CAR28870.1 - 0.027 14.2 0.1 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 2 TPR_11 PF13414.6 CAR28870.1 - 0.041 13.6 2.7 14 5.4 0.0 3.8 4 0 0 4 4 4 0 TPR repeat Phage_CP76 PF06892.11 CAR28870.1 - 0.074 12.6 0.1 0.77 9.3 0.0 2.3 2 0 0 2 2 2 0 Phage regulatory protein CII (CP76) PocR PF10114.9 CAR28870.1 - 0.1 12.3 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Sensory domain found in PocR TPR_21 PF09976.9 CAR28870.1 - 0.11 12.2 0.7 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain ANAPC3 PF12895.7 CAR28870.1 - 0.16 12.2 4.4 1.1 9.6 1.0 3.5 3 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SH3_1 PF00018.28 CAR28871.1 - 5e-13 48.4 0.0 5e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CAR28871.1 - 1.8e-12 46.9 0.1 5.1e-12 45.5 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR28871.1 - 2.6e-06 27.0 0.0 5.9e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Cwf_Cwc_15 PF04889.12 CAR28872.1 - 7e-19 68.5 44.7 3.8e-08 33.4 38.0 3.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 CAR28872.1 - 0.018 13.3 18.5 0.02 13.1 18.5 1.0 1 0 0 1 1 1 0 Nop14-like family Merozoite_SPAM PF07133.11 CAR28872.1 - 0.022 14.7 23.5 0.027 14.5 23.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Nop53 PF07767.11 CAR28872.1 - 0.024 14.0 27.0 0.091 12.1 27.0 1.8 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Adaptin_binding PF10199.9 CAR28872.1 - 0.13 12.9 17.4 0.051 14.2 15.3 1.4 2 0 0 2 2 1 0 Alpha and gamma adaptin binding protein p34 ANXA2R PF15721.5 CAR28872.1 - 0.21 12.1 5.7 0.28 11.7 5.7 1.2 1 0 0 1 1 1 0 Annexin-2 receptor DNA_pol_phi PF04931.13 CAR28872.1 - 0.24 9.5 23.0 0.31 9.1 23.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi GCIP PF13324.6 CAR28872.1 - 0.36 10.4 8.2 0.4 10.3 8.2 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 CAR28872.1 - 0.53 10.7 16.9 0.9 10.0 16.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3381 PF11861.8 CAR28872.1 - 0.66 9.8 18.1 1.3 8.8 18.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF2151 PF10221.9 CAR28872.1 - 0.83 8.2 11.1 0.98 7.9 11.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 CAR28872.1 - 1.5 7.0 19.4 1.8 6.7 19.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 CAR28872.1 - 2 6.5 11.8 2.3 6.2 11.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TRAP_alpha PF03896.16 CAR28872.1 - 2.6 7.2 9.6 3.5 6.7 9.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sporozoite_P67 PF05642.11 CAR28872.1 - 3.8 5.5 10.7 4.2 5.3 10.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4637 PF15470.6 CAR28872.1 - 8.6 6.1 13.9 14 5.4 13.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) SLS PF14611.6 CAR28873.1 - 1e-45 156.3 0.4 2.1e-45 155.3 0.4 1.6 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator DUF2726 PF10881.8 CAR28873.1 - 0.027 14.4 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2726) Importin_rep_6 PF18829.1 CAR28874.1 - 0.18 12.0 3.0 0.45 10.7 3.0 1.7 1 0 0 1 1 1 0 Importin repeat 6 Pro_dh PF01619.18 CAR28875.1 - 1.4e-60 205.4 0.1 1.7e-60 205.0 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Diphthami_syn_2 PF01902.17 CAR28876.1 - 4.7e-37 127.6 0.0 1.3e-36 126.2 0.0 1.7 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CAR28876.1 - 2.2e-17 63.2 0.0 1e-08 35.2 0.0 2.6 2 0 0 2 2 2 2 Endoribonuclease L-PSP Mito_fiss_reg PF05308.11 CAR28877.1 - 0.76 9.8 14.0 0.38 10.8 2.3 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Sec1 PF00995.23 CAR28878.1 - 8.4e-92 309.2 3.1 1e-91 308.9 3.1 1.1 1 0 0 1 1 1 1 Sec1 family DUF3113 PF11310.8 CAR28878.1 - 0.018 14.9 0.0 0.082 12.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) Glyco_hydro81C PF17652.1 CAR28879.1 - 5.9e-153 509.2 5.9 7.5e-153 508.9 5.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CAR28879.1 - 2.5e-99 332.5 0.2 3.5e-99 332.0 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain DUF4477 PF14780.6 CAR28880.1 - 0.017 14.7 5.4 2.1 8.0 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) Spermine_synth PF01564.17 CAR28881.1 - 8.2e-65 217.8 0.0 1.4e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CAR28881.1 - 1.8e-23 82.2 0.0 2.9e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CAR28881.1 - 0.038 14.7 0.0 0.1 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CAR28881.1 - 0.04 14.6 0.1 0.11 13.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox_2 PF07992.14 CAR28881.1 - 0.14 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 CAR28882.1 - 0.00014 22.6 1.9 0.36 11.8 0.8 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.15 CAR28882.1 - 0.00068 19.0 0.1 0.0075 15.6 0.0 2.4 3 0 0 3 3 3 1 CPSF A subunit region Lactonase PF10282.9 CAR28882.1 - 0.0089 15.3 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Sec5 PF15469.6 CAR28884.1 - 3.3e-55 186.9 3.4 3.3e-55 186.9 3.4 2.6 3 0 0 3 3 3 1 Exocyst complex component Sec5 COG2 PF06148.11 CAR28884.1 - 0.012 15.8 3.5 0.012 15.8 3.5 3.1 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Nucleocap_ssRNA PF11128.8 CAR28884.1 - 0.026 14.3 0.1 0.1 12.3 0.0 2.0 1 1 1 2 2 2 0 Plant viral coat protein nucleocapsid Vps51 PF08700.11 CAR28884.1 - 2.4 8.3 6.6 0.33 11.0 1.4 2.4 2 0 0 2 2 2 0 Vps51/Vps67 LSM PF01423.22 CAR28885.1 - 1.3e-15 56.8 0.5 1.6e-15 56.5 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAR28885.1 - 0.03 14.5 0.1 0.038 14.1 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 CAR28885.1 - 0.069 13.3 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain Pep3_Vps18 PF05131.14 CAR28886.1 - 2.6e-43 147.4 0.2 1e-42 145.4 0.0 2.2 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CAR28886.1 - 8.9e-10 38.6 4.7 8.9e-10 38.6 4.7 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CAR28886.1 - 1.2e-05 25.7 4.0 1.5e-05 25.4 1.0 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 CAR28886.1 - 0.00081 19.4 3.3 0.0029 17.6 3.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CAR28886.1 - 0.00094 19.5 3.5 0.00094 19.5 3.5 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAR28886.1 - 0.0098 15.7 3.6 0.032 14.1 3.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CAR28886.1 - 0.026 14.1 0.8 0.026 14.1 0.8 2.5 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CAR28886.1 - 0.028 14.2 5.7 0.1 12.4 5.7 2.1 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 CAR28886.1 - 0.081 12.9 11.1 0.31 11.0 11.1 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CAR28886.1 - 0.16 11.9 3.8 0.49 10.3 3.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 CAR28886.1 - 0.54 10.3 4.0 1.3 9.1 4.0 1.7 1 0 0 1 1 1 0 Zinc-finger zf-rbx1 PF12678.7 CAR28886.1 - 0.68 10.3 4.9 0.22 11.8 1.2 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain CS PF04969.16 CAR28886.1 - 2.8 9.0 7.6 2.9 9.0 0.2 3.8 4 1 0 4 4 4 0 CS domain TFIID_30kDa PF03540.13 CAR28887.1 - 1.5e-24 85.6 0.1 2.5e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CDC37_N PF03234.14 CAR28888.1 - 1.8e-44 151.8 4.4 1.8e-44 151.8 4.4 4.2 3 2 2 5 5 5 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 CAR28888.1 - 5.8e-43 145.6 6.1 1.5e-42 144.2 6.1 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 CAR28888.1 - 6.9e-29 99.9 8.2 6.9e-29 99.9 8.2 3.5 3 1 0 3 3 3 1 Cdc37 C terminal domain DUF2415 PF10313.9 CAR28889.1 - 2.2e-21 75.5 0.5 2.2e-21 75.5 0.5 2.5 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Trnau1ap PF17654.1 CAR28889.1 - 0.26 12.1 0.0 0.26 12.1 0.0 2.3 2 1 0 2 2 2 0 Selenocysteine tRNA 1 associated proteins Stb3 PF10330.9 CAR28890.1 - 2.1e-31 107.8 0.0 4.5e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Putative Sin3 binding protein TRAP_alpha PF03896.16 CAR28890.1 - 0.072 12.3 5.0 0.15 11.3 5.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.12 CAR28890.1 - 1.5 8.1 11.4 2.6 7.3 11.4 1.5 1 0 0 1 1 1 0 NOA36 protein Stm1_N PF09598.10 CAR28891.1 - 5.7e-10 39.9 10.8 5.7e-10 39.9 10.8 4.5 4 2 1 5 5 5 1 Stm1 UPF0561 PF10573.9 CAR28891.1 - 0.31 11.2 8.4 0.73 10.0 8.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0561 LRRC37 PF15779.5 CAR28891.1 - 4.2 7.8 10.2 1.5 9.2 6.5 2.2 2 1 0 2 2 2 0 Leucine-rich repeat-containing protein 37 family GRP PF07172.11 CAR28891.1 - 8.8 7.1 14.8 0.064 13.9 4.1 2.5 2 1 0 2 2 2 0 Glycine rich protein family NUDIX PF00293.28 CAR28892.1 - 5e-12 46.0 0.0 1.1e-11 44.9 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain Mem_trans PF03547.18 CAR28893.1 - 9e-29 100.0 2.8 3.3e-28 98.2 2.8 1.8 1 1 0 1 1 1 1 Membrane transport protein AMP-binding PF00501.28 CAR28894.1 - 9.1e-85 284.8 0.0 1.1e-84 284.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAR28894.1 - 4.1e-24 85.3 0.1 1.1e-23 84.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CAR28894.1 - 2.3e-19 69.1 0.5 5.2e-19 67.9 0.5 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Sec7 PF01369.20 CAR28895.1 - 6e-71 237.9 0.6 1.7e-70 236.4 0.6 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CAR28895.1 - 2.7e-41 141.1 0.9 2.7e-41 141.1 0.9 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CAR28895.1 - 3.5e-28 97.3 0.5 3.5e-28 97.3 0.5 5.0 6 0 0 6 6 6 2 Domain of unknown function (DUF1981) DCB PF16213.5 CAR28895.1 - 6e-17 61.9 2.2 1.2e-16 60.9 0.2 2.6 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 GTP_CH_N PF12471.8 CAR28896.1 - 1.1e-82 276.4 0.0 1.7e-82 275.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 CAR28896.1 - 2.8e-18 66.0 0.0 4.1e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II HSP20 PF00011.21 CAR28897.1 - 8.2e-10 38.8 0.0 8.2e-10 38.8 0.0 2.4 3 0 0 3 3 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CAR28897.1 - 9.2e-06 25.1 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF3807 PF12720.7 CAR28897.1 - 0.051 13.8 16.6 0.026 14.8 7.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) PTPRCAP PF15713.5 CAR28897.1 - 0.09 13.1 18.2 0.27 11.5 1.2 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated AUX_IAA PF02309.16 CAR28897.1 - 0.091 12.6 2.1 0.16 11.8 2.1 1.3 1 0 0 1 1 1 0 AUX/IAA family UPF0560 PF10577.9 CAR28897.1 - 1.1 7.7 17.4 1.6 7.1 0.4 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 RNA_pol_Rpc4 PF05132.14 CAR28897.1 - 1.2 9.5 14.2 5.6 7.4 10.9 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 CAR28897.1 - 3 8.0 12.4 19 5.4 7.7 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal GREB1 PF15782.5 CAR28897.1 - 3.1 4.8 8.3 3.9 4.5 8.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Plasmodium_Vir PF05795.11 CAR28897.1 - 3.9 6.8 8.8 0.23 10.8 1.9 1.9 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Sec62 PF03839.16 CAR28897.1 - 4.8 6.6 6.5 1.8 8.0 1.3 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 DUF913 PF06025.12 CAR28897.1 - 4.8 6.0 7.9 46 2.8 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Band_3_cyto PF07565.13 CAR28897.1 - 5.2 6.8 8.1 0.31 10.8 1.3 1.9 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PcfK PF14058.6 CAR28897.1 - 7.3 6.9 20.4 2.1 8.6 2.0 2.5 2 0 0 2 2 2 0 PcfK-like protein AIF_C PF14721.6 CAR28897.1 - 9.2 6.6 10.9 61 4.0 0.0 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM163 PF15069.6 CAR28897.1 - 9.4 6.7 10.8 1.9 8.9 2.7 2.2 2 0 0 2 2 2 0 FAM163 family GTP_EFTU PF00009.27 CAR28898.1 - 7.3e-44 149.6 1.1 1e-43 149.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CAR28898.1 - 5.9e-35 120.0 0.5 5.9e-35 120.0 0.5 2.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CAR28898.1 - 3.2e-08 33.8 0.3 1.5e-07 31.7 0.3 2.3 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CAR28898.1 - 0.0029 17.7 0.4 0.038 14.1 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase CDC27 PF09507.10 CAR28898.1 - 0.014 14.8 25.4 0.022 14.2 25.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CPSF100_C PF13299.6 CAR28898.1 - 4.9 7.3 10.2 11 6.2 10.2 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2052 PF09747.9 CAR28898.1 - 9.7 6.3 15.4 20 5.3 15.4 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) IPK PF03770.16 CAR28899.1 - 6e-54 182.9 0.2 7.5e-54 182.6 0.2 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase CRCB PF02537.15 CAR28900.1 - 1.7e-28 98.8 11.9 2.8e-17 62.8 4.4 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Gpi1 PF05024.15 CAR28900.1 - 0.019 15.0 6.1 0.036 14.2 6.1 1.4 1 0 0 1 1 1 0 N-acetylglucosaminyl transferase component (Gpi1) DUF5305 PF17231.2 CAR28900.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Ribosomal_S6e PF01092.19 CAR28901.1 - 2e-58 195.8 0.1 4.1e-58 194.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Pyr_redox_2 PF07992.14 CAR28902.1 - 5.5e-64 216.2 1.9 5.6e-64 216.2 1.1 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CAR28902.1 - 1e-34 119.1 1.4 1.2e-33 115.7 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CAR28902.1 - 6.1e-19 68.4 9.9 1.4e-18 67.2 1.8 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR28902.1 - 1.5e-16 60.5 4.4 6.5e-16 58.5 4.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAR28902.1 - 5.4e-08 32.0 6.4 0.02 13.6 0.0 4.0 3 1 1 4 4 4 3 HI0933-like protein AlaDh_PNT_C PF01262.21 CAR28902.1 - 1.2e-07 31.3 1.8 0.0017 17.7 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 CAR28902.1 - 5.7e-07 29.0 0.0 1.4e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 CAR28902.1 - 5.2e-06 25.8 6.7 0.00017 20.8 1.4 2.6 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 CAR28902.1 - 9.8e-06 25.2 0.0 9.8e-06 25.2 0.0 1.5 2 0 0 2 2 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CAR28902.1 - 0.0033 16.7 2.7 0.23 10.7 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 CAR28902.1 - 0.0095 16.4 0.1 3.9 8.0 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 CAR28902.1 - 0.016 14.6 2.1 0.63 9.4 0.0 3.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CAR28902.1 - 0.09 12.7 0.2 0.09 12.7 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CAR28902.1 - 0.12 12.0 0.4 0.28 10.7 0.4 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 CAR28902.1 - 0.49 9.7 1.9 0.51 9.7 0.2 1.8 2 0 0 2 2 2 0 ThiF family SLAC1 PF03595.17 CAR28903.1 - 5.6e-70 236.2 32.1 6.4e-70 236.0 32.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Neurensin PF14927.6 CAR28903.1 - 0.0036 17.0 1.0 0.4 10.4 0.0 2.9 3 0 0 3 3 3 2 Neurensin MFS_1 PF07690.16 CAR28904.1 - 5.1e-47 160.5 34.0 3.4e-43 147.9 16.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR28904.1 - 3.2e-18 65.8 29.0 4e-18 65.5 5.9 3.2 2 1 0 2 2 2 2 Sugar (and other) transporter NOG1_N PF17835.1 CAR28905.1 - 1.8e-49 167.8 1.3 1.5e-48 164.8 0.1 2.6 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 CAR28905.1 - 5.9e-27 93.4 1.4 5.9e-27 93.4 1.4 2.1 2 0 0 2 2 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 CAR28905.1 - 2.6e-25 88.0 0.2 6.5e-25 86.7 0.2 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CAR28905.1 - 2.1e-16 60.0 0.0 5.8e-16 58.6 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR28905.1 - 3e-08 33.4 0.0 5.8e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CAR28905.1 - 0.0011 18.4 0.1 0.0022 17.4 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CAR28905.1 - 0.0029 17.5 0.2 2.5 8.0 0.1 3.4 4 0 0 4 4 4 2 RsgA GTPase AAA_16 PF13191.6 CAR28905.1 - 0.0055 17.1 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.23 CAR28905.1 - 0.048 13.7 0.0 9.1 6.3 0.0 2.8 1 1 1 2 2 2 0 Dynamin family Roc PF08477.13 CAR28905.1 - 0.13 12.5 0.0 0.38 11.0 0.0 1.9 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CAR28905.1 - 1.3 9.5 7.9 17 5.8 7.9 2.7 1 1 0 1 1 1 0 AAA domain Sec62 PF03839.16 CAR28906.1 - 2.1e-72 243.1 0.0 2.7e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 MARVEL PF01284.23 CAR28906.1 - 0.0019 18.3 0.1 0.0024 17.9 0.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain SPC12 PF06645.13 CAR28906.1 - 2.5 8.2 6.3 0.45 10.6 1.3 2.1 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) FixP_N PF14715.6 CAR28906.1 - 4.8 7.0 6.9 21 4.9 0.2 2.3 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Dynamin_N PF00350.23 CAR28907.1 - 2.1e-17 63.7 1.1 5.2e-17 62.4 0.1 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CAR28907.1 - 2.2e-09 37.4 0.0 1e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR28907.1 - 1e-07 31.7 0.0 9.2e-06 25.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 CAR28907.1 - 0.022 13.8 1.0 0.071 12.2 0.0 2.3 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) PARP_reg PF02877.14 CAR28907.1 - 0.026 14.6 1.4 0.22 11.6 0.0 3.0 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase, regulatory domain PPV_E1_C PF00519.17 CAR28907.1 - 0.033 13.0 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 Papillomavirus helicase AAA_18 PF13238.6 CAR28907.1 - 0.046 14.3 0.0 2.4 8.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain CVNH PF08881.10 CAR28907.1 - 0.083 13.6 0.3 0.41 11.4 0.1 2.1 2 0 0 2 2 2 0 CVNH domain Abhydrolase_1 PF00561.20 CAR28908.1 - 1.6e-21 77.1 0.0 3.2e-21 76.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CAR28908.1 - 1e-08 34.7 0.0 3.2e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CAR28908.1 - 0.0055 17.3 0.0 0.012 16.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 CAR28908.1 - 0.006 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Phage_TAC_9 PF10876.8 CAR28908.1 - 0.047 13.8 0.1 0.1 12.7 0.1 1.5 1 0 0 1 1 1 0 Phage tail assemb.y chaperone protein, TAC DUF915 PF06028.11 CAR28908.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) ORC3_N PF07034.11 CAR28908.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Transglut_core PF01841.19 CAR28909.1 - 2e-12 47.5 0.1 5e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 CAR28909.1 - 1.4e-09 37.8 1.5 3.4e-09 36.5 1.5 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain PAW PF04721.17 CAR28909.1 - 0.12 12.2 1.7 0.19 11.5 1.7 1.4 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW IBR PF01485.21 CAR28909.1 - 0.27 11.5 3.7 0.58 10.4 1.4 2.4 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 CAR28909.1 - 2.2 8.3 6.6 6.4 6.8 5.6 2.3 2 1 0 2 2 2 0 Transposase zinc-ribbon domain tRNA-synt_1b PF00579.25 CAR28910.1 - 4.1e-72 243.0 0.0 5.5e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 CAR28910.1 - 0.00017 21.4 0.1 0.00035 20.4 0.1 1.6 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain Romo1 PF10247.9 CAR28911.1 - 1.2e-28 99.2 8.2 1.7e-28 98.8 8.2 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 SH3_10 PF17902.1 CAR28911.1 - 0.033 14.3 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 SH3 domain DUF2681 PF10883.8 CAR28912.1 - 0.018 15.4 0.4 0.018 15.4 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Peptidase_M56 PF05569.11 CAR28912.1 - 0.023 13.9 0.4 0.029 13.6 0.4 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 WD40 PF00400.32 CAR28913.1 - 0.0036 18.1 4.2 0.058 14.3 0.1 3.9 5 0 0 5 5 5 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CAR28913.1 - 0.013 14.3 0.2 3.8 6.1 0.0 2.8 3 0 0 3 3 3 0 Nup133 N terminal like ILEI PF15711.5 CAR28913.1 - 0.082 13.4 0.1 0.4 11.2 0.0 2.3 2 0 0 2 2 2 0 Interleukin-like EMT inducer PAXNEB PF05625.11 CAR28914.1 - 2.7e-94 316.3 0.2 3.2e-94 316.1 0.2 1.1 1 0 0 1 1 1 1 PAXNEB protein Lipoprotein_3 PF00938.17 CAR28914.1 - 0.05 13.8 0.0 0.86 9.8 0.0 2.8 3 0 0 3 3 3 0 Lipoprotein Lactamase_B_2 PF12706.7 CAR28915.1 - 9.5e-31 106.9 0.9 1.5e-30 106.3 0.9 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CAR28915.1 - 5.5e-11 42.6 0.2 8.6e-11 42.0 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain VWA_3 PF13768.6 CAR28915.1 - 0.081 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Pantoate_transf PF02548.15 CAR28916.1 - 2.7e-94 315.4 0.0 3.2e-94 315.1 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase Asp_Glu_race PF01177.22 CAR28916.1 - 5e-05 23.2 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase PEP_mutase PF13714.6 CAR28916.1 - 0.00011 21.7 0.1 0.00024 20.6 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase tRNA-synt_2 PF00152.20 CAR28917.1 - 4.3e-98 328.3 0.1 5.7e-98 327.9 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAR28917.1 - 2.7e-06 27.3 0.2 5.3e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CAR28917.1 - 0.0043 16.6 1.1 0.078 12.4 0.1 2.9 3 1 0 3 3 3 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 CAR28917.1 - 0.047 13.7 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.32 CAR28918.1 - 1.3e-25 89.2 11.4 7.4e-07 29.8 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR28918.1 - 2.9e-19 69.2 0.0 8.2e-05 22.8 0.0 5.8 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR28918.1 - 4.9e-05 22.5 0.2 1 8.2 0.0 4.3 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CAR28918.1 - 9.8e-05 21.2 0.1 0.17 10.5 0.0 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CAR28918.1 - 0.0011 18.9 0.0 0.069 13.0 0.0 3.1 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CAR28918.1 - 0.0027 16.3 0.0 0.046 12.2 0.0 2.0 1 1 0 2 2 2 1 Cytochrome D1 heme domain WD40_like PF17005.5 CAR28918.1 - 0.004 16.5 0.0 0.058 12.7 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain PD40 PF07676.12 CAR28918.1 - 0.064 13.2 0.0 2.2 8.3 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF5046 PF16465.5 CAR28918.1 - 0.075 12.5 0.0 23 4.3 0.0 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF5046) Frtz PF11768.8 CAR28918.1 - 0.1 10.9 0.1 0.17 10.1 0.0 1.4 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Coatomer_WDAD PF04053.14 CAR28918.1 - 0.11 11.5 0.0 1.4 7.9 0.0 2.4 2 1 0 2 2 2 0 Coatomer WD associated region UMP1 PF05348.11 CAR28919.1 - 1.5e-41 141.4 0.3 1.7e-41 141.1 0.3 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 GYF PF02213.16 CAR28920.1 - 2.6e-15 55.8 0.1 5.6e-15 54.7 0.1 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CAR28920.1 - 0.12 12.2 0.2 0.37 10.6 0.2 1.9 1 0 0 1 1 1 0 GYF domain 2 Sec66 PF09802.9 CAR28921.1 - 5.2e-70 234.7 1.7 6e-70 234.5 1.7 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 TMEM154 PF15102.6 CAR28921.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family NPL4 PF05021.15 CAR28922.1 - 5.4e-138 459.5 0.0 8.5e-138 458.9 0.0 1.3 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CAR28922.1 - 3.5e-66 221.8 1.0 5.7e-66 221.1 1.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 CAR28922.1 - 2.2e-06 28.1 0.0 6.6e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Metallophos PF00149.28 CAR28923.1 - 0.00021 21.8 0.0 0.00047 20.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Hpt PF01627.23 CAR28924.1 - 2.1e-10 40.7 0.4 3.6e-10 39.9 0.4 1.6 1 1 0 1 1 1 1 Hpt domain MgsA_C PF12002.8 CAR28925.1 - 3.6e-51 173.4 0.0 6.3e-51 172.6 0.0 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CAR28925.1 - 1.8e-21 76.3 0.3 4.4e-21 75.0 0.1 1.8 2 0 0 2 2 1 1 AAA C-terminal domain AAA PF00004.29 CAR28925.1 - 6.1e-15 55.8 0.0 1e-14 55.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CAR28925.1 - 2.3e-13 50.2 0.0 5e-13 49.1 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CAR28925.1 - 1.6e-08 34.7 0.0 2.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAR28925.1 - 7.9e-08 32.4 0.0 2.1e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAR28925.1 - 4.1e-07 30.5 0.4 0.00057 20.3 0.1 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CAR28925.1 - 1.8e-06 28.2 0.7 0.00016 21.9 0.7 2.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CAR28925.1 - 2.8e-05 24.3 0.0 0.00017 21.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 CAR28925.1 - 3.7e-05 23.5 0.0 0.00031 20.5 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CAR28925.1 - 6.8e-05 22.4 0.2 0.15 11.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CAR28925.1 - 0.00039 20.2 0.0 0.0012 18.6 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 CAR28925.1 - 0.00045 20.8 0.0 0.0012 19.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 CAR28925.1 - 0.00085 19.7 0.1 0.02 15.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.6 CAR28925.1 - 0.0013 19.1 0.8 1 9.7 0.3 2.3 1 1 1 2 2 2 2 AAA domain AAA_24 PF13479.6 CAR28925.1 - 0.0024 17.6 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CAR28925.1 - 0.003 18.1 0.1 0.0076 16.8 0.0 1.9 1 1 1 2 2 1 1 ABC transporter DUF815 PF05673.13 CAR28925.1 - 0.0033 16.6 0.0 0.0057 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 CAR28925.1 - 0.0037 16.5 0.0 0.0083 15.3 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 CAR28925.1 - 0.0052 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RNF220 PF15926.5 CAR28925.1 - 0.0075 15.9 1.8 0.0075 15.9 1.8 1.7 1 1 1 2 2 2 1 E3 ubiquitin-protein ligase RNF220 IstB_IS21 PF01695.17 CAR28925.1 - 0.0077 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 CAR28925.1 - 0.011 15.4 0.3 0.028 14.2 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 CAR28925.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CAR28925.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 CAR28925.1 - 0.022 14.9 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 CAR28925.1 - 0.023 14.9 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CAR28925.1 - 0.025 14.5 0.1 0.26 11.2 0.0 2.2 1 1 0 2 2 2 0 RsgA GTPase TniB PF05621.11 CAR28925.1 - 0.033 13.6 0.1 1.6 8.1 0.0 2.2 1 1 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 CAR28925.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf_C2HC_14 PF18574.1 CAR28925.1 - 0.073 12.9 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 C2HC Zing finger domain ATPase_2 PF01637.18 CAR28925.1 - 0.077 12.9 0.1 1.2 9.0 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea ResIII PF04851.15 CAR28925.1 - 0.084 12.9 1.6 1.2 9.1 0.7 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Roc PF08477.13 CAR28925.1 - 0.15 12.3 0.1 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 CAR28925.1 - 0.15 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Hydrolase_6 PF13344.6 CAR28926.1 - 3.9e-28 97.5 0.0 1.3e-27 95.8 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR28926.1 - 5.2e-14 52.1 0.0 8.8e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CAR28926.1 - 1.6e-08 35.1 0.0 3.2e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAR28926.1 - 9.9e-05 22.5 0.3 0.09 12.9 0.0 2.5 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Glyco_transf_22 PF03901.17 CAR28927.1 - 5.8e-86 289.3 23.6 7.4e-86 289.0 23.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family RRM_5 PF13893.6 CAR28927.1 - 0.24 11.0 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adenylsucc_synt PF00709.21 CAR28928.1 - 1.4e-175 584.3 0.0 1.6e-175 584.1 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF1033 PF06279.11 CAR28928.1 - 0.16 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) POP1 PF06978.11 CAR28929.1 - 6.6e-75 251.6 11.5 1.4e-74 250.6 11.5 1.6 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CAR28929.1 - 1.2e-32 112.1 0.6 3.1e-32 110.8 0.6 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.11 CAR28929.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain GDPD_2 PF13653.6 CAR28930.1 - 0.034 14.6 0.6 0.07 13.6 0.6 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 CAR28930.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Amidohydro_1 PF01979.20 CAR28931.1 - 5.6e-83 279.1 0.0 6.9e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CAR28931.1 - 4.2e-09 36.4 0.1 1.8e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Ssu72 PF04722.13 CAR28932.1 - 3.4e-85 284.4 0.0 3.8e-85 284.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Peptidase_C54 PF03416.19 CAR28933.1 - 5.5e-81 272.0 0.0 6.9e-81 271.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 G-patch PF01585.23 CAR28934.1 - 1e-11 44.5 3.6 1e-11 44.5 3.6 2.2 2 0 0 2 2 2 1 G-patch domain R3H PF01424.22 CAR28934.1 - 0.03 14.3 0.1 0.095 12.7 0.0 2.0 2 0 0 2 2 2 0 R3H domain Paf1 PF03985.13 CAR28934.1 - 0.17 10.9 31.1 0.066 12.2 28.2 1.9 2 0 0 2 2 2 0 Paf1 Raftlin PF15250.6 CAR28934.1 - 1.3 7.7 12.3 2.2 7.0 12.3 1.3 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 CAR28934.1 - 2.1 6.5 30.3 4.2 5.5 30.3 1.5 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 CAR28934.1 - 5 6.4 38.7 14 4.9 38.7 1.7 1 0 0 1 1 1 0 BUD22 SID PF11778.8 CAR28935.1 - 2.3e-58 196.1 1.2 2.3e-58 196.1 1.2 3.3 3 0 0 3 3 3 2 Septation initiation FAM76 PF16046.5 CAR28935.1 - 0.0034 16.8 12.6 0.0034 16.8 12.6 6.3 1 1 6 7 7 7 3 FAM76 protein ERM PF00769.19 CAR28935.1 - 0.0045 16.8 15.0 0.0045 16.8 15.0 5.2 2 1 2 4 4 4 1 Ezrin/radixin/moesin family Jnk-SapK_ap_N PF09744.9 CAR28935.1 - 0.011 16.0 15.1 0.011 16.0 15.1 6.8 3 1 2 6 6 6 0 JNK_SAPK-associated protein-1 PKcGMP_CC PF16808.5 CAR28935.1 - 0.03 14.2 0.9 0.03 14.2 0.9 11.3 9 3 3 12 12 12 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF3584 PF12128.8 CAR28935.1 - 6.7 4.1 108.3 0.39 8.2 18.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) DnaJ PF00226.31 CAR28936.1 - 2.1e-23 82.2 0.5 2.1e-23 82.2 0.5 2.5 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 CAR28936.1 - 1.9e-08 34.4 3.1 4.5e-08 33.2 3.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAR28936.1 - 1.8e-06 28.1 2.3 4e-06 27.0 2.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CAR28936.1 - 0.00043 20.6 0.7 0.0019 18.5 0.7 2.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 CAR28936.1 - 0.0045 16.9 0.4 0.011 15.7 0.4 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CAR28936.1 - 0.0099 16.3 1.0 0.03 14.8 1.0 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf_C2H2_ZHX PF18387.1 CAR28936.1 - 0.095 12.4 1.0 0.25 11.0 1.0 1.6 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain AKAP95 PF04988.12 CAR28936.1 - 2.4 8.4 13.0 0.056 13.7 5.7 2.1 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) GST_C PF00043.25 CAR28937.1 - 1.9e-24 85.7 0.0 5e-24 84.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CAR28937.1 - 1.3e-18 67.1 0.0 3.9e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CAR28937.1 - 1.3e-10 41.5 0.0 2.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CAR28937.1 - 2.8e-09 37.1 0.0 5.8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CAR28937.1 - 1.8e-05 24.8 0.0 5.2e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAR28937.1 - 0.04 14.0 0.0 0.086 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Phage_GPO PF05929.11 CAR28937.1 - 0.24 11.0 5.2 0.39 10.3 5.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase SprA-related PF12118.8 CAR28937.1 - 1.3 8.1 16.8 1.7 7.7 16.8 1.1 1 0 0 1 1 1 0 SprA-related family Activator_LAG-3 PF11498.8 CAR28937.1 - 1.9 7.3 25.9 2.8 6.8 25.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Spt20 PF12090.8 CAR28937.1 - 3.2 7.3 19.3 4.8 6.7 19.3 1.3 1 0 0 1 1 1 0 Spt20 family CDI PF02234.19 CAR28937.1 - 3.7 7.8 0.0 3.7 7.8 0.0 3.5 3 1 0 3 3 2 0 Cyclin-dependent kinase inhibitor TFIIA PF03153.13 CAR28937.1 - 6.8 6.6 20.6 9.7 6.1 20.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM199X PF15814.5 CAR28937.1 - 7.6 5.5 6.2 13 4.8 6.2 1.3 1 0 0 1 1 1 0 Protein family FAM199X Elongin_A PF06881.11 CAR28938.1 - 5.6e-17 62.2 16.8 3e-12 47.0 0.4 3.0 2 1 1 3 3 3 2 RNA polymerase II transcription factor SIII (Elongin) subunit A SOG2 PF10428.9 CAR28938.1 - 0.5 9.5 13.9 0.63 9.2 13.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CRAL_TRIO PF00650.20 CAR28939.1 - 1.1e-39 135.7 0.0 1.5e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CAR28939.1 - 8.7e-17 61.1 0.5 2.2e-16 59.8 0.5 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain EXOSC1 PF10447.9 CAR28940.1 - 4.9e-42 143.0 1.1 7.5e-42 142.4 0.3 1.7 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 S1 PF00575.23 CAR28940.1 - 0.098 13.0 0.0 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 S1 RNA binding domain DUF5370 PF17340.2 CAR28940.1 - 0.13 12.1 0.2 1.9 8.4 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5370) PDZ_5 PF17817.1 CAR28941.1 - 0.0023 18.2 1.1 0.0092 16.2 0.0 2.7 2 0 0 2 2 2 1 PDZ domain Globin PF00042.22 CAR28942.1 - 3.1e-07 30.9 0.1 3.2e-06 27.7 0.0 2.6 2 1 0 2 2 2 1 Globin Med16 PF11635.8 CAR28943.1 - 4.8e-216 719.2 12.6 5.5e-216 719.0 12.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Nicastrin PF05450.15 CAR28943.1 - 0.044 13.2 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Nicastrin Ytp1 PF10355.9 CAR28944.1 - 1.4e-55 188.4 20.9 2.1e-53 181.3 20.9 2.3 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) Ni_hydr_CYTB PF01292.20 CAR28944.1 - 6.9 6.2 26.5 14 5.2 7.2 4.2 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 Peptidase_S8 PF00082.22 CAR28945.1 - 5.6e-40 137.5 0.1 1.4e-39 136.1 0.1 1.7 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CAR28945.1 - 2.6e-24 85.0 0.5 6.4e-24 83.8 0.5 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF1180 PF06679.12 CAR28945.1 - 0.00053 20.4 0.2 0.0012 19.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Mucin PF01456.17 CAR28945.1 - 5.9 6.9 17.8 17 5.4 17.8 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_C1_2 PF03051.15 CAR28946.1 - 2.8e-160 533.9 0.8 3.1e-160 533.7 0.8 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 CAR28946.1 - 1.8e-05 24.9 0.1 0.24 11.5 0.0 2.5 2 0 0 2 2 2 2 Papain family cysteine protease Fe_hyd_lg_C PF02906.14 CAR28947.1 - 1.3e-58 198.6 0.0 1.7e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Cys_Met_Meta_PP PF01053.20 CAR28948.1 - 1.6e-67 227.7 0.0 4.6e-67 226.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CAR28948.1 - 3.7e-05 22.9 0.0 5.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CAR28948.1 - 0.0044 16.2 0.0 0.025 13.8 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II G6PD_C PF02781.16 CAR28949.1 - 1.6e-106 355.8 0.0 2.1e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CAR28949.1 - 3.5e-58 197.2 0.0 1.9e-57 194.7 0.0 2.0 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain RhoGAP PF00620.27 CAR28950.1 - 3.6e-35 121.0 0.0 9.2e-35 119.7 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 CAR28950.1 - 1.1e-31 108.8 49.1 1.3e-14 54.2 4.5 4.4 4 0 0 4 4 4 4 LIM domain ATG2_CAD PF13329.6 CAR28951.1 - 7.1e-34 116.8 1.4 3e-33 114.7 0.1 2.5 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 CAR28951.1 - 1.9e-28 98.7 0.1 4.8e-28 97.4 0.1 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 CAR28951.1 - 0.006 16.4 0.1 0.028 14.2 0.1 2.3 1 1 0 1 1 1 1 Vacuolar-sorting-associated 13 protein C-terminal Sir1 PF11603.8 CAR28952.1 - 1.2e-29 103.2 3.5 1.6e-27 96.4 0.1 2.9 2 1 0 2 2 2 2 Regulatory protein Sir1 Rep_fac-A_C PF08646.10 CAR28952.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Replication factor-A C terminal domain PALP PF00291.25 CAR28953.1 - 2e-59 201.4 0.0 2.5e-59 201.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Med3 PF11593.8 CAR28954.1 - 0.0048 16.1 12.1 0.0053 16.0 12.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF4813 PF16072.5 CAR28954.1 - 0.0074 16.0 18.3 0.0087 15.8 18.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4813) PepSY_TM PF03929.16 CAR28954.1 - 0.31 10.7 2.5 0.37 10.4 2.5 1.1 1 0 0 1 1 1 0 PepSY-associated TM region TFIIA PF03153.13 CAR28954.1 - 1.7 8.6 5.8 1.9 8.4 5.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Homeodomain PF00046.29 CAR28955.1 - 4.7e-07 29.6 0.2 1e-06 28.5 0.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CAR28955.1 - 2.7e-06 27.2 0.2 2.7e-06 27.2 0.2 2.1 2 1 0 2 2 2 1 Homeobox KN domain Syntaxin_2 PF14523.6 CAR28955.1 - 0.66 10.4 5.0 0.49 10.8 0.2 2.7 2 1 1 3 3 3 0 Syntaxin-like protein MATalpha_HMGbox PF04769.12 CAR28956.1 - 4.1e-11 42.6 0.3 7.8e-11 41.7 0.3 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box ANTH PF07651.16 CAR28957.1 - 3.4e-67 226.4 0.0 4.9e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 ANTH domain SUI1 PF01253.22 CAR28958.1 - 9.9e-28 96.5 1.2 1.3e-27 96.1 1.2 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Bromo_TP_like PF17027.5 CAR28958.1 - 0.015 15.4 0.2 0.14 12.3 0.0 2.0 1 1 1 2 2 2 0 Histone-fold protein RIB43A PF05914.12 CAR28959.1 - 0.031 13.0 7.1 0.033 12.9 7.1 1.0 1 0 0 1 1 1 0 RIB43A Cir_N PF10197.9 CAR28959.1 - 0.079 13.2 7.2 0.14 12.4 7.2 1.4 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR tRNA-synt_1e PF01406.19 CAR28960.1 - 1.3e-136 454.9 0.6 2.6e-136 453.9 0.6 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CAR28960.1 - 3.1e-08 32.8 0.2 2e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CAR28960.1 - 8.1e-05 21.1 0.0 0.00021 19.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) LCAT PF02450.15 CAR28961.1 - 5.5e-07 29.1 0.0 1.5e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 CAR28961.1 - 1.1e-05 25.3 0.1 2.2e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CAR28961.1 - 0.0004 21.1 0.0 0.0011 19.7 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF900 PF05990.12 CAR28961.1 - 0.00057 19.5 0.1 0.001 18.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 CAR28961.1 - 0.0006 19.1 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 CAR28961.1 - 0.003 17.2 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_1 PF00561.20 CAR28961.1 - 0.0081 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CAR28961.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_5 PF12695.7 CAR28961.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DnaJ PF00226.31 CAR28962.1 - 1e-17 64.0 1.6 1.4e-17 63.5 1.6 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 CAR28962.1 - 7.4e-17 60.8 2.9 1.3e-16 60.0 2.9 1.4 1 0 0 1 1 1 1 CSL zinc finger ROQ_II PF18386.1 CAR28962.1 - 0.021 14.6 0.9 5.9 6.8 0.1 2.2 2 0 0 2 2 2 0 Roquin II domain RNA_pol_I_A49 PF06870.12 CAR28963.1 - 2.9e-124 414.9 0.6 3.3e-124 414.7 0.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Exo5 PF09810.9 CAR28963.1 - 0.24 10.9 0.5 0.35 10.3 0.3 1.4 1 1 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease FGGY_C PF02782.16 CAR28964.1 - 5.1e-24 85.1 0.0 8e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CAR28964.1 - 7.4e-10 38.8 0.0 1.3e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 CAR28964.1 - 0.00011 21.9 0.0 0.0045 16.5 0.0 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Raco_middle PF17651.1 CAR28964.1 - 0.059 13.1 0.0 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 RACo middle region AAA_23 PF13476.6 CAR28965.1 - 2.6e-30 106.5 24.8 2.6e-30 106.5 24.8 8.4 2 1 3 5 5 5 1 AAA domain Rad50_zn_hook PF04423.14 CAR28965.1 - 8.2e-16 57.6 0.8 8.2e-16 57.6 0.8 7.0 6 0 0 6 6 6 1 Rad50 zinc hook motif SMC_N PF02463.19 CAR28965.1 - 1.7e-07 30.9 0.1 1.7e-07 30.9 0.1 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CAR28965.1 - 3.3e-06 27.2 0.0 9.7e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 CAR28965.1 - 1.4e-05 25.1 26.8 0.00017 21.5 0.0 4.6 4 2 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CAR28965.1 - 0.00019 21.2 98.7 0.013 15.2 22.0 5.1 1 1 2 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 CAR28965.1 - 0.0005 19.8 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain bZIP_1 PF00170.21 CAR28965.1 - 0.011 15.9 0.7 0.011 15.9 0.7 10.7 9 3 3 12 12 12 0 bZIP transcription factor AAA_13 PF13166.6 CAR28965.1 - 0.013 14.2 0.0 0.013 14.2 0.0 7.6 2 1 4 7 7 7 0 AAA domain AAA_16 PF13191.6 CAR28965.1 - 0.058 13.8 3.3 0.11 12.9 0.0 3.2 3 1 0 3 3 3 0 AAA ATPase domain RRM_1 PF00076.22 CAR28966.1 - 0.00021 21.0 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 CAR28966.1 - 0.00024 21.8 0.0 0.00062 20.5 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 CAR28966.1 - 0.018 15.1 0.0 0.075 13.2 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif OS-D PF03392.13 CAR28966.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D CTK3 PF12243.8 CAR28966.1 - 0.074 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 RNA_bind PF08675.11 CAR28966.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA binding domain MRP-L46 PF11788.8 CAR28967.1 - 1.4e-38 132.3 0.1 2.6e-38 131.4 0.1 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Vezatin PF12632.7 CAR28967.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes WD40 PF00400.32 CAR28968.1 - 2.9e-14 53.2 7.1 0.0077 17.1 0.0 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR28968.1 - 1.4e-09 38.1 2.9 0.0058 16.9 0.0 4.6 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CAR28968.1 - 0.0034 16.2 0.1 0.0081 15.0 0.1 1.6 2 0 0 2 2 2 1 Nup133 N terminal like Ge1_WD40 PF16529.5 CAR28968.1 - 0.011 14.8 0.0 0.97 8.3 0.0 2.9 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DapH_N PF08503.10 CAR28968.1 - 0.057 13.7 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal DUF5046 PF16465.5 CAR28968.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) RTC4 PF14474.6 CAR28969.1 - 1.1e-33 116.0 0.1 1.7e-33 115.4 0.1 1.3 1 0 0 1 1 1 1 RTC4-like domain DEAD_2 PF06733.15 CAR28969.1 - 0.066 12.8 0.1 0.14 11.7 0.1 1.6 1 1 1 2 2 2 0 DEAD_2 IBB PF01749.20 CAR28969.1 - 0.78 10.2 8.3 3.5 8.1 1.5 2.6 1 1 1 2 2 2 0 Importin beta binding domain zf-CCHC PF00098.23 CAR28970.1 - 3e-51 169.3 53.1 2.4e-08 33.7 3.0 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CAR28970.1 - 2.6e-15 55.9 41.5 0.0061 16.3 0.8 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 CAR28970.1 - 1.2e-06 28.4 48.1 0.11 12.4 1.2 7.0 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 CAR28970.1 - 8.5e-06 25.4 37.2 0.58 9.9 1.3 7.0 3 2 4 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 CAR28970.1 - 0.039 13.8 2.2 0.039 13.8 2.2 6.8 7 0 0 7 7 7 0 Zinc knuckle TRAF6_Z2 PF18048.1 CAR28970.1 - 7.8 6.7 18.7 14 5.8 0.1 5.5 5 2 0 5 5 5 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_9 PF14369.6 CAR28970.1 - 7.9 6.8 29.9 2.2 8.6 1.1 5.2 3 2 0 3 3 3 0 zinc-ribbon zf-CCHC_2 PF13696.6 CAR28970.1 - 9.2 6.2 53.0 0.31 10.9 1.0 7.3 7 0 0 7 7 7 0 Zinc knuckle Pterin_bind PF00809.22 CAR28971.1 - 1.3e-53 182.2 0.0 2.5e-53 181.3 0.0 1.5 1 1 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 CAR28971.1 - 5.3e-36 123.6 0.0 2.1e-19 70.1 0.0 2.6 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 CAR28971.1 - 2.6e-34 118.1 0.3 6.9e-34 116.7 0.1 1.9 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FAD_binding_3 PF01494.19 CAR28972.1 - 5.6e-22 78.4 0.1 4.8e-15 55.7 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 CAR28972.1 - 3.1e-05 23.2 0.1 0.00052 19.2 0.2 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CAR28972.1 - 0.00043 19.6 0.0 0.0012 18.1 0.0 1.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 CAR28972.1 - 0.00055 19.1 0.0 0.00088 18.4 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 CAR28972.1 - 0.0006 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CAR28972.1 - 0.00094 19.4 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CAR28972.1 - 0.0032 16.4 0.0 0.039 12.8 0.0 2.3 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.24 CAR28972.1 - 0.0052 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CAR28972.1 - 0.0065 17.0 0.0 0.16 12.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CAR28972.1 - 0.0081 15.4 0.0 0.018 14.3 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 CAR28972.1 - 0.018 14.3 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CAR28972.1 - 0.024 13.7 0.1 0.035 13.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 CAR28972.1 - 0.032 13.0 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pro_isomerase PF00160.21 CAR28973.1 - 1.7e-15 57.6 0.0 2.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CAR28973.1 - 1.5e-14 53.5 0.0 3.2e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR28973.1 - 0.03 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CAR28973.1 - 0.1 12.7 0.0 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif DUF1428 PF07237.11 CAR28973.1 - 0.17 12.2 0.0 7.9 6.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1428) DUF676 PF05057.14 CAR28974.1 - 2.8e-06 27.0 0.0 5.2e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CAR28974.1 - 2.8e-05 24.1 0.0 0.0002 21.3 0.0 2.1 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 CAR28974.1 - 4.3e-05 23.3 0.0 7.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 CAR28974.1 - 0.00062 19.5 0.0 0.0013 18.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.11 CAR28974.1 - 0.0016 17.9 0.0 0.012 15.0 0.0 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 CAR28974.1 - 0.0095 16.6 0.0 0.018 15.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 CAR28974.1 - 0.068 12.3 0.0 0.16 11.1 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase VASt PF16016.5 CAR28975.1 - 8.4e-16 58.7 0.3 2.3e-15 57.3 0.3 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain PH PF00169.29 CAR28975.1 - 1.3e-13 51.4 4.7 1.6e-13 51.1 1.0 2.9 3 0 0 3 3 3 1 PH domain BAR_3 PF16746.5 CAR28975.1 - 1.8e-11 44.2 1.4 5.5e-11 42.6 1.4 1.9 1 0 0 1 1 1 1 BAR domain of APPL family Vps51 PF08700.11 CAR28975.1 - 0.019 15.0 0.4 0.065 13.3 0.4 1.9 1 0 0 1 1 1 0 Vps51/Vps67 PDDEXK_9 PF08011.11 CAR28975.1 - 0.36 10.8 4.3 1.2 9.1 0.1 2.7 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Dsl1_N PF11988.8 CAR28976.1 - 1.8e-125 418.6 11.2 1.8e-125 418.6 11.2 1.6 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 N terminal Dsl1_C PF11989.8 CAR28976.1 - 8.4e-73 244.2 3.7 2e-72 243.0 3.7 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal CABIT PF12736.7 CAR28976.1 - 0.032 13.5 0.1 0.06 12.6 0.1 1.4 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, HMA PF00403.26 CAR28977.1 - 3.4e-09 37.0 0.2 4.1e-09 36.7 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 CAR28977.1 - 0.064 13.6 0.0 0.17 12.3 0.0 1.7 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Yae1_N PF09811.9 CAR28978.1 - 2.4e-09 36.7 3.9 4.4e-09 35.9 3.9 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal GYF PF02213.16 CAR28979.1 - 8.7e-09 34.9 2.2 1.7e-08 34.0 2.2 1.5 1 0 0 1 1 1 1 GYF domain ORC5_C PF14630.6 CAR28980.1 - 4.9e-60 203.5 0.9 1.6e-59 201.8 0.2 1.9 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 CAR28980.1 - 1.2e-06 29.0 0.0 3.1e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR28980.1 - 0.00016 22.0 0.0 0.00039 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CAR28980.1 - 0.016 15.1 0.3 0.36 10.7 0.3 2.2 1 1 0 1 1 1 0 NACHT domain ResIII PF04851.15 CAR28980.1 - 0.024 14.6 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CAR28980.1 - 0.048 14.0 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CAR28980.1 - 0.082 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Torsin PF06309.11 CAR28980.1 - 0.092 12.9 0.0 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 Torsin Ubiq-Cytc-red_N PF09165.10 CAR28980.1 - 0.11 13.4 0.1 0.47 11.4 0.0 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal DUF1744 PF08490.12 CAR28981.1 - 1.1e-132 442.4 2.6 1.6e-132 441.8 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CAR28981.1 - 1.8e-77 260.8 5.0 5.5e-77 259.2 2.4 2.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CAR28981.1 - 2e-12 46.6 1.4 2e-12 46.6 1.4 3.8 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CAR28981.1 - 2.4e-06 27.4 0.5 2.5e-05 24.1 0.5 2.4 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CAR28981.1 - 0.00027 21.0 0.3 0.0024 17.9 0.0 2.8 2 0 0 2 2 2 1 RNase_H superfamily DUF4358 PF14270.6 CAR28981.1 - 0.54 10.6 2.5 21 5.5 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) zf_UBZ PF18439.1 CAR28981.1 - 1.6 8.4 5.1 0.63 9.7 0.6 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger YIF1 PF03878.15 CAR28982.1 - 9.6e-77 257.7 9.4 1.1e-76 257.5 9.4 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 CAR28982.1 - 0.1 12.3 10.5 0.28 10.9 10.5 1.8 1 1 0 1 1 1 0 Yip1 domain DUF202 PF02656.15 CAR28982.1 - 0.94 10.0 3.5 9.5 6.8 3.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DnaJ PF00226.31 CAR28983.1 - 2.6e-17 62.7 0.9 8.5e-17 61.0 0.9 2.0 1 0 0 1 1 1 1 DnaJ domain CRAL_TRIO PF00650.20 CAR28984.1 - 3.3e-38 130.9 0.0 4.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CAR28984.1 - 7.8e-13 48.4 0.1 1.5e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ArAE_2_N PF10337.9 CAR28985.1 - 1.2e-55 189.4 4.5 1.2e-55 189.4 4.5 2.9 3 1 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CAR28985.1 - 1e-13 51.5 12.9 1e-13 51.5 12.9 2.8 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 CAR28985.1 - 9.7e-08 31.3 1.5 1.1e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter ArAE_2 PF10334.9 CAR28985.1 - 0.00035 20.5 0.2 0.00089 19.2 0.0 1.7 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ArAE_1 PF06081.11 CAR28985.1 - 4.8 7.3 5.9 4.2 7.5 1.8 3.0 2 1 0 2 2 2 0 Aromatic acid exporter family member 1 UFD1 PF03152.14 CAR28986.1 - 1.3e-69 233.1 0.0 1.7e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 TPR_12 PF13424.6 CAR28987.1 - 2.1e-11 43.9 5.1 0.011 16.0 0.0 6.2 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CAR28987.1 - 3.9e-11 42.3 7.2 0.0025 17.6 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAR28987.1 - 4.1e-11 43.2 4.9 0.0012 19.3 0.0 5.3 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAR28987.1 - 5e-11 41.8 13.2 0.003 17.5 0.0 8.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAR28987.1 - 1.9e-09 37.6 0.3 0.2 12.4 0.0 7.0 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CAR28987.1 - 4.1e-09 36.9 1.6 0.28 11.9 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CAR28987.1 - 4.2e-08 33.0 10.9 0.11 13.0 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR28987.1 - 2.2e-07 30.6 10.9 3.6e-05 23.6 0.0 7.5 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAR28987.1 - 7e-07 29.3 0.0 0.12 12.5 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CAR28987.1 - 1.4e-06 28.7 1.5 9.4 7.4 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR28987.1 - 3.5e-05 23.9 8.0 0.44 10.8 0.2 4.5 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CAR28987.1 - 9.4e-05 22.0 6.6 0.15 11.7 0.0 5.2 5 1 0 5 5 5 2 TPR repeat TPR_20 PF14561.6 CAR28987.1 - 0.00086 19.6 1.0 7.3 7.0 0.2 4.3 4 1 0 4 4 3 1 Tetratricopeptide repeat DASH_Dad3 PF08656.10 CAR28987.1 - 0.0027 17.8 1.5 1.6 8.9 0.1 3.3 3 1 0 3 3 3 2 DASH complex subunit Dad3 TPPII_N PF12583.8 CAR28987.1 - 0.035 14.7 0.2 12 6.5 0.0 2.6 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Alkyl_sulf_dimr PF14863.6 CAR28987.1 - 0.054 14.0 1.0 1.2 9.5 0.0 3.1 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_7 PF13176.6 CAR28987.1 - 0.089 12.9 0.0 0.089 12.9 0.0 5.3 7 0 0 7 7 6 0 Tetratricopeptide repeat Tau95_N PF17682.1 CAR28987.1 - 0.22 11.7 2.7 18 5.6 0.1 2.8 2 0 0 2 2 2 0 Tau95 Triple barrel domain Ist1 PF03398.14 CAR28988.1 - 5.1e-59 198.9 1.6 6.9e-59 198.4 1.6 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Mei5_like PF17021.5 CAR28988.1 - 1.4 8.9 7.1 0.63 10.1 1.2 2.5 2 1 1 3 3 3 0 Putative double-strand recombination repair-like Tam41_Mmp37 PF09139.11 CAR28989.1 - 8.2e-92 308.1 5.1 3.8e-85 286.2 0.8 2.1 1 1 1 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial PI3_PI4_kinase PF00454.27 CAR28990.1 - 3.7e-32 112.1 0.2 3.7e-32 112.1 0.2 3.0 3 1 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 CAR28990.1 - 1.4e-19 69.8 0.0 4.1e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 CAR28990.1 - 1.6e-07 30.9 2.0 4e-07 29.6 2.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 CAR28990.1 - 0.033 13.5 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) AA_permease PF00324.21 CAR28991.1 - 5e-134 447.5 43.4 6e-134 447.2 43.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR28991.1 - 8.8e-34 117.0 44.8 1.1e-33 116.7 44.8 1.1 1 0 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.8 CAR28991.1 - 0.047 13.3 1.9 1.2 8.8 0.6 3.0 2 0 0 2 2 2 0 Intrinsic membrane protein PufX AA_permease PF00324.21 CAR28992.1 - 5.1e-139 464.0 47.0 6.2e-139 463.7 47.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR28992.1 - 6.7e-26 91.1 50.3 1.1e-25 90.4 50.3 1.3 1 0 0 1 1 1 1 Amino acid permease FH2 PF02181.23 CAR28993.1 - 4.3e-87 292.6 6.4 4.3e-87 292.6 6.4 3.7 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CAR28993.1 - 2e-35 122.2 0.2 2e-35 122.2 0.2 4.6 5 0 0 5 5 5 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 CAR28993.1 - 6.3e-28 97.6 7.8 6.3e-28 97.6 7.8 4.6 3 1 1 4 4 4 1 Diaphanous GTPase-binding Domain Sec2p PF06428.11 CAR28994.1 - 5.7e-25 87.1 12.7 5.7e-25 87.1 12.7 4.0 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p PHD_3 PF13922.6 CAR28994.1 - 1.6 9.2 0.0 1.6 9.2 0.0 4.6 4 0 0 4 4 4 0 PHD domain of transcriptional enhancer, Asx Aa_trans PF01490.18 CAR28995.1 - 5.9e-79 265.7 31.6 6.8e-79 265.5 31.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TIMELESS PF04821.14 CAR28996.1 - 7.7e-89 297.6 3.1 1.9e-88 296.3 3.1 1.7 1 0 0 1 1 1 1 Timeless protein Peptidase_S8 PF00082.22 CAR28997.1 - 8.6e-19 67.9 1.8 1.2e-18 67.4 1.8 1.2 1 0 0 1 1 1 1 Subtilase family Cyclin_N PF00134.23 CAR28998.1 - 3e-39 133.7 7.3 4.2e-37 126.7 1.6 2.6 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 CAR28998.1 - 3.6e-08 33.5 1.6 5.4e-08 32.9 0.2 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Sad1_UNC PF07738.13 CAR28999.1 - 1.6e-30 105.8 0.3 4.6e-30 104.3 0.0 2.0 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Peptidase_M1_N PF17900.1 CAR29000.1 - 0.00013 22.2 0.2 0.054 13.7 0.0 2.7 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 CAR29000.1 - 0.00025 20.7 0.1 0.0011 18.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M1 domain CDC45 PF02724.14 CAR29000.1 - 2.8 6.1 11.4 5.2 5.2 11.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Oxidored_FMN PF00724.20 CAR29001.1 - 2.3e-65 221.1 0.0 3e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family 2-Hacid_dh_C PF02826.19 CAR29002.1 - 1.8e-54 183.8 0.0 3.3e-54 182.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAR29002.1 - 7e-13 48.4 0.0 9.7e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CAR29002.1 - 6.7e-05 23.1 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CAR29002.1 - 0.038 13.6 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HCO3_cotransp PF00955.21 CAR29004.1 - 2.3e-79 267.5 13.1 3.6e-40 138.3 3.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family CYYR1 PF10873.8 CAR29004.1 - 0.15 12.5 0.7 17 5.8 0.2 2.7 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 Per1 PF04080.13 CAR29005.1 - 4.7e-87 292.0 11.6 6.3e-87 291.5 11.6 1.2 1 0 0 1 1 1 1 Per1-like family Spindle_Spc25 PF08234.12 CAR29006.1 - 3e-18 65.8 0.2 3e-18 65.8 0.2 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Bacillus_HBL PF05791.11 CAR29006.1 - 0.037 13.9 0.5 0.037 13.9 0.5 2.1 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Spc24 PF08286.11 CAR29006.1 - 0.15 12.3 14.5 0.4 10.9 4.6 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 CAR29006.1 - 0.37 10.1 11.4 0.53 9.6 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CCDC53 PF10152.9 CAR29006.1 - 0.83 10.1 5.4 1.5 9.2 5.4 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Sec8_exocyst PF04048.14 CAR29006.1 - 0.93 9.4 8.7 0.19 11.6 1.0 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Vfa1 PF08432.10 CAR29006.1 - 1 9.6 5.6 1.6 9.0 5.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 OmpH PF03938.14 CAR29006.1 - 3.2 8.1 18.3 8.1 6.8 18.3 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Exonuc_VII_L PF02601.15 CAR29006.1 - 3.5 7.1 13.6 4.4 6.8 13.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Exo_endo_phos PF03372.23 CAR29007.1 - 6.9e-15 55.2 0.2 9.4e-15 54.8 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2207 PF09972.9 CAR29007.1 - 0.0038 16.1 0.2 0.0055 15.5 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) 2TM PF13239.6 CAR29007.1 - 0.035 14.4 0.6 0.074 13.4 0.6 1.5 1 0 0 1 1 1 0 2TM domain DUF4231 PF14015.6 CAR29007.1 - 0.1 13.0 0.3 0.19 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) CDP-OH_P_transf PF01066.21 CAR29007.1 - 0.18 12.6 2.0 0.4 11.5 2.0 1.5 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase Glyco_transf_28 PF03033.20 CAR29008.1 - 3e-33 114.8 0.2 1.3e-32 112.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 CAR29008.1 - 5.7e-27 93.8 0.3 4e-19 68.6 0.0 3.6 3 1 0 3 3 3 2 GRAM domain UDPGT PF00201.18 CAR29008.1 - 4.1e-09 35.8 0.2 4.1e-08 32.5 0.2 2.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 CAR29008.1 - 1.6e-08 35.0 0.2 6.2e-08 33.1 0.2 2.1 1 0 0 1 1 1 1 PH domain Glyco_tran_28_C PF04101.16 CAR29008.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PH_11 PF15413.6 CAR29008.1 - 0.14 12.6 0.1 0.61 10.5 0.1 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain Abhydrolase_1 PF00561.20 CAR29009.1 - 3.5e-68 230.0 0.0 4.2e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR29009.1 - 8.6e-05 23.2 0.1 0.00016 22.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR29009.1 - 0.0062 15.8 0.0 0.057 12.7 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 CAR29009.1 - 0.016 14.9 0.3 0.029 14.0 0.3 1.3 1 0 0 1 1 1 0 Putative esterase ABC_membrane PF00664.23 CAR29010.1 - 1.5e-60 205.2 0.5 2.1e-60 204.7 0.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CAR29010.1 - 5.7e-31 107.9 0.0 3.1e-30 105.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CAR29010.1 - 1.7e-06 27.7 1.9 0.00027 20.4 0.0 2.6 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CAR29010.1 - 0.00028 21.3 0.1 0.0057 17.1 0.0 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 CAR29010.1 - 0.00043 20.8 0.0 0.0064 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CAR29010.1 - 0.00076 19.2 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CAR29010.1 - 0.0017 18.7 0.1 0.023 15.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CAR29010.1 - 0.0028 17.4 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein DEAD PF00270.29 CAR29010.1 - 0.0072 16.1 0.0 0.039 13.7 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_21 PF13304.6 CAR29010.1 - 0.0074 16.1 0.2 0.085 12.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 CAR29010.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin T2SSE PF00437.20 CAR29010.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 CAR29010.1 - 0.028 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CAR29010.1 - 0.037 13.7 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase RsgA_GTPase PF03193.16 CAR29010.1 - 0.038 13.9 0.2 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 CAR29010.1 - 0.044 14.2 0.0 0.48 10.9 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 CAR29010.1 - 0.06 13.4 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 CAR29010.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 CAR29010.1 - 0.13 12.7 1.4 0.32 11.5 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAR29010.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SbcCD_C PF13558.6 CAR29010.1 - 0.18 12.1 0.7 1.5 9.1 0.7 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 CAR29010.1 - 0.19 11.3 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 CAR29010.1 - 0.21 11.4 0.0 0.5 10.2 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase PrgI PF12666.7 CAR29010.1 - 0.78 10.5 3.3 3.6 8.4 0.0 2.8 3 0 0 3 3 2 0 PrgI family protein PH PF00169.29 CAR29011.1 - 4.5e-08 33.6 0.1 1e-06 29.2 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 CAR29011.1 - 0.16 12.4 0.1 0.4 11.1 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain YbaJ PF10757.9 CAR29012.1 - 0.016 15.8 0.3 0.095 13.3 0.3 2.3 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ DUF948 PF06103.11 CAR29012.1 - 1.7 9.0 9.9 8.3 6.8 0.9 3.2 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) EMG1 PF03587.14 CAR29013.1 - 2.1e-78 262.5 0.0 2.4e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase RP854 PF17460.2 CAR29013.1 - 0.031 14.0 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein RP854 LCD1 PF09798.9 CAR29014.1 - 2.8e-198 660.3 32.3 3.2e-198 660.2 32.3 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein FapA PF03961.13 CAR29014.1 - 3.3 6.2 7.9 6.3 5.3 7.9 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Ribosomal_L37e PF01907.19 CAR29015.1 - 3.3e-27 94.4 9.9 5.8e-27 93.6 9.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e zf-ribbon_3 PF13248.6 CAR29015.1 - 0.0012 18.2 1.1 0.0019 17.5 1.1 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 CAR29015.1 - 0.0014 18.6 1.4 0.0021 18.0 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 CAR29015.1 - 0.095 12.4 2.9 3.8 7.3 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 CAR29015.1 - 0.16 11.8 2.3 0.28 11.0 2.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-NADH-PPase PF09297.11 CAR29015.1 - 0.25 11.0 7.1 2 8.2 6.9 2.3 1 1 1 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C3HC4 PF00097.25 CAR29015.1 - 0.54 10.2 4.6 0.86 9.5 4.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FHA PF00498.26 CAR29016.1 - 2.5e-08 34.1 0.0 1.3e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 FHA domain Swi6_N PF18530.1 CAR29017.1 - 6.5e-45 151.7 0.3 6.5e-45 151.7 0.3 2.6 3 0 0 3 3 3 1 Swi6 N-terminal domain Ank_5 PF13857.6 CAR29017.1 - 6.4e-11 42.3 0.7 0.00064 20.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR29017.1 - 7.8e-11 42.4 0.4 0.00011 22.7 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CAR29017.1 - 1.4e-10 40.4 0.5 0.0024 18.2 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CAR29017.1 - 4.6e-08 33.2 0.8 0.0029 18.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CAR29017.1 - 2.1e-07 31.3 0.5 0.0052 17.3 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) ADIP PF11559.8 CAR29017.1 - 0.0053 16.8 4.7 0.0053 16.8 4.7 3.1 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding SesA PF17107.5 CAR29017.1 - 0.048 13.9 4.9 2.4 8.4 0.1 2.6 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SUIM_assoc PF16619.5 CAR29017.1 - 0.053 13.6 8.1 0.13 12.4 8.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 FmiP_Thoc5 PF09766.9 CAR29017.1 - 0.18 11.0 11.1 0.055 12.7 4.1 2.3 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Cob_adeno_trans PF01923.18 CAR29017.1 - 0.27 11.3 2.4 0.75 9.9 1.0 2.3 2 0 0 2 2 2 0 Cobalamin adenosyltransferase Phage_GPO PF05929.11 CAR29017.1 - 0.55 9.8 9.4 0.019 14.6 2.1 2.0 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Spt20 PF12090.8 CAR29017.1 - 1 8.9 9.7 2.9 7.4 9.7 1.7 1 0 0 1 1 1 0 Spt20 family Seryl_tRNA_N PF02403.22 CAR29017.1 - 1.2 9.4 8.2 1.3 9.3 5.2 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HIP1_clath_bdg PF16515.5 CAR29017.1 - 1.8 9.2 18.4 0.12 13.1 6.5 3.4 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FapA PF03961.13 CAR29017.1 - 7 5.1 8.0 0.39 9.3 1.2 2.1 2 0 0 2 2 2 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 CAR29017.1 - 8.9 5.8 12.0 0.55 9.7 4.7 2.3 2 1 0 2 2 2 0 Exonuclease VII, large subunit FlxA PF14282.6 CAR29017.1 - 10 6.2 21.4 2.4 8.2 3.4 2.7 2 0 0 2 2 2 0 FlxA-like protein Vta1 PF04652.16 CAR29018.1 - 5.9e-36 123.6 0.7 5.9e-36 123.6 0.7 1.7 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 CAR29018.1 - 6.4e-15 54.6 0.5 1.2e-14 53.7 0.5 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain IP_trans PF02121.18 CAR29018.1 - 0.049 13.2 0.3 0.071 12.7 0.3 1.3 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein MitMem_reg PF13012.6 CAR29018.1 - 0.053 13.9 0.0 0.2 12.1 0.0 1.9 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Rib_recp_KP_reg PF05104.12 CAR29018.1 - 0.053 14.6 11.8 0.079 14.0 11.8 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region S-AdoMet_synt_C PF02773.16 CAR29019.1 - 6.4e-64 214.1 0.0 1.1e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 CAR29019.1 - 2.3e-44 150.1 0.2 4.8e-44 149.1 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 CAR29019.1 - 1.9e-43 147.5 0.0 3.9e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 CAR29019.1 - 0.044 12.6 0.3 0.14 10.9 0.2 1.9 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) PAP2 PF01569.21 CAR29020.1 - 1.2e-20 73.7 0.9 1.2e-20 73.7 0.9 1.7 2 0 0 2 2 2 1 PAP2 superfamily BCLP PF12304.8 CAR29020.1 - 0.0021 17.6 0.9 0.0078 15.8 0.2 2.1 2 0 0 2 2 2 1 Beta-casein like protein PAP2_3 PF14378.6 CAR29020.1 - 0.0062 16.2 1.5 0.015 15.0 1.3 1.7 2 0 0 2 2 2 1 PAP2 superfamily FUSC_2 PF13515.6 CAR29020.1 - 0.54 10.4 5.0 0.096 12.8 0.6 2.0 3 0 0 3 3 3 0 Fusaric acid resistance protein-like DUF4149 PF13664.6 CAR29020.1 - 0.88 9.9 4.2 1.4 9.2 0.0 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4149) PBP PF01161.20 CAR29021.1 - 1.6e-19 70.5 0.0 2e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PSP1 PF04468.12 CAR29022.1 - 2.8e-43 146.1 0.0 8.9e-43 144.5 0.0 2.0 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Cu-oxidase_2 PF07731.14 CAR29023.1 - 1.8e-29 102.2 0.4 2e-28 98.9 0.1 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CAR29023.1 - 1.7e-22 79.7 4.7 3e-19 69.2 1.0 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CAR29023.1 - 2.4e-17 63.5 0.7 3.7e-14 53.1 0.1 3.6 4 1 0 4 4 4 2 Multicopper oxidase Orf78 PF06024.12 CAR29023.1 - 0.033 14.5 0.0 0.07 13.4 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) OATP PF03137.20 CAR29023.1 - 0.14 10.4 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4064 PF13273.6 CAR29023.1 - 0.34 11.2 1.7 0.5 10.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Pkinase PF00069.25 CAR29024.1 - 2.7e-69 233.5 0.0 6e-69 232.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 CAR29024.1 - 1.5e-32 111.8 2.4 1.5e-32 111.8 2.4 2.4 2 0 0 2 2 2 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 CAR29024.1 - 4.2e-32 111.5 0.0 1.4e-31 109.7 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR29024.1 - 0.00035 20.0 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like TBP PF00352.21 CAR29024.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.7 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) APH PF01636.23 CAR29024.1 - 0.18 11.7 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Rad60-SLD PF11976.8 CAR29025.1 - 6.5e-19 67.5 0.1 8.3e-19 67.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CAR29025.1 - 1.3e-13 50.4 0.0 1.6e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family AA_permease PF00324.21 CAR29026.1 - 1.6e-124 416.1 31.7 2e-124 415.8 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR29026.1 - 6.3e-37 127.4 30.9 7.3e-37 127.2 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease Colicin_im PF03857.13 CAR29026.1 - 0.68 9.9 4.3 0.41 10.6 1.1 2.1 2 0 0 2 2 2 0 Colicin immunity protein Nitroreductase PF00881.24 CAR29027.1 - 0.00013 22.1 0.1 0.00032 20.8 0.1 1.6 1 1 0 1 1 1 1 Nitroreductase family SKG6 PF08693.10 CAR29028.1 - 0.0033 16.8 0.0 0.0084 15.5 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SH3_9 PF14604.6 CAR29028.1 - 0.0042 16.9 0.0 0.01 15.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CAR29028.1 - 0.02 14.5 0.0 0.057 13.0 0.0 1.8 1 0 0 1 1 1 0 SH3 domain CAP PF00188.26 CAR29029.1 - 2.4e-19 70.4 2.6 2.4e-19 70.4 2.6 2.8 2 1 0 2 2 2 1 Cysteine-rich secretory protein family DUF2798 PF11391.8 CAR29029.1 - 0.17 12.0 8.4 1.5 8.9 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) TPR_19 PF14559.6 CAR29030.1 - 0.0049 17.4 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAR29030.1 - 0.012 15.7 0.0 0.035 14.2 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAR29030.1 - 0.05 14.3 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAR29030.1 - 0.19 12.7 0.0 0.42 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_20 PF14561.6 CAR29030.1 - 0.22 11.9 0.1 0.41 11.0 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat CAP_GLY PF01302.25 CAR29031.1 - 1.9e-14 53.4 1.8 2.2e-14 53.2 0.1 2.0 3 0 0 3 3 3 1 CAP-Gly domain Exonuc_VII_L PF02601.15 CAR29031.1 - 0.003 17.2 2.9 0.0043 16.7 2.9 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit Spc29 PF17082.5 CAR29031.1 - 0.0032 17.3 12.3 0.11 12.3 2.3 2.7 1 1 2 3 3 3 2 Spindle Pole Component 29 Angiomotin_C PF12240.8 CAR29031.1 - 0.0077 15.8 12.2 0.022 14.3 12.1 1.8 1 1 0 1 1 1 1 Angiomotin C terminal CLIP1_ZNF PF16641.5 CAR29031.1 - 0.013 15.4 0.4 0.023 14.5 0.4 1.5 1 0 0 1 1 1 0 CLIP1 zinc knuckle Allexi_40kDa PF05549.11 CAR29031.1 - 0.072 12.6 6.0 0.038 13.5 2.9 1.8 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF536 PF04394.14 CAR29031.1 - 0.32 10.9 15.8 0.91 9.4 3.0 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF536 Spc7 PF08317.11 CAR29031.1 - 1.1 8.1 20.7 0.12 11.2 1.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Nup54 PF13874.6 CAR29031.1 - 1.8 8.7 12.9 4.7 7.3 12.9 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 KxDL PF10241.9 CAR29031.1 - 1.8 8.9 13.5 1.2 9.4 7.4 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein Lebercilin PF15619.6 CAR29031.1 - 1.9 8.1 23.5 0.65 9.6 14.4 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fib_alpha PF08702.10 CAR29031.1 - 7.5 6.7 15.1 0.56 10.4 2.1 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Histidinol_dh PF00815.20 CAR29032.1 - 3.6e-160 533.5 2.6 6e-160 532.7 2.6 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 CAR29032.1 - 1e-26 92.5 0.1 2.6e-26 91.3 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 CAR29032.1 - 1.6e-14 54.1 0.2 4.3e-14 52.7 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Complex1_LYR_2 PF13233.6 CAR29033.1 - 3.5e-18 66.1 0.4 3.5e-18 66.1 0.4 1.7 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.15 CAR29033.1 - 2.8e-11 43.3 0.4 6.6e-11 42.1 0.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF4028 PF13220.6 CAR29033.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4028) RRM_Rrp7 PF17799.1 CAR29034.1 - 3.6e-43 147.2 1.2 4.6e-43 146.8 0.2 1.6 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 CAR29034.1 - 1.2e-24 86.7 10.0 2.6e-24 85.6 9.7 1.8 1 1 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Lipin_mid PF16876.5 CAR29034.1 - 0.028 14.6 0.1 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain RRM_1 PF00076.22 CAR29034.1 - 0.036 13.9 2.0 27 4.7 0.0 3.8 4 0 0 4 4 4 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAM_Ste50p PF09235.10 CAR29035.1 - 6.9e-27 93.5 2.3 1.5e-26 92.4 2.3 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif RA PF00788.23 CAR29035.1 - 6.1e-15 55.6 0.1 1.3e-14 54.5 0.1 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 CAR29035.1 - 0.043 14.3 0.1 0.094 13.2 0.1 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF3128 PF11326.8 CAR29036.1 - 2.7e-26 91.7 1.5 3e-26 91.6 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) SelR PF01641.18 CAR29037.1 - 2.7e-49 166.3 0.3 3.3e-49 166.0 0.3 1.1 1 0 0 1 1 1 1 SelR domain Ntox15 PF15604.6 CAR29037.1 - 0.11 12.7 0.2 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 Novel toxin 15 VHS PF00790.19 CAR29038.1 - 1.5e-06 28.1 0.1 2.9e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 CAR29038.1 - 0.00011 22.5 0.8 0.0015 18.8 0.0 2.3 2 0 0 2 2 2 1 GAT domain EutC PF05985.11 CAR29038.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine ammonia-lyase light chain (EutC) Glutaredoxin PF00462.24 CAR29039.1 - 2.3e-13 50.2 0.0 3.5e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 CAR29039.1 - 0.0056 17.1 0.1 0.012 16.1 0.1 1.7 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 CAR29039.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 CAR29039.1 - 0.05 13.4 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin RNase_T PF00929.24 CAR29041.1 - 0.0055 17.3 0.0 0.015 15.9 0.0 1.7 1 0 0 1 1 1 1 Exonuclease La PF05383.17 CAR29042.1 - 7.2e-16 58.0 0.0 1.6e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 La domain SelP_N PF04592.14 CAR29042.1 - 0.97 8.8 0.0 0.97 8.8 0.0 3.5 2 1 1 3 3 3 0 Selenoprotein P, N terminal region ATG22 PF11700.8 CAR29043.1 - 9.8e-153 509.2 25.1 1.1e-152 509.0 25.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 CAR29043.1 - 2.4e-08 33.3 37.8 8.9e-08 31.4 15.6 3.4 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1761 PF08570.10 CAR29043.1 - 5.7 7.2 18.6 5.2 7.4 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1761) TssN PF17555.2 CAR29043.1 - 7.8 5.8 22.8 0.083 12.3 8.0 3.1 3 1 0 3 3 3 0 Type VI secretion system, TssN WD40 PF00400.32 CAR29044.1 - 2.2e-16 59.9 1.8 0.011 16.6 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29044.1 - 1.1e-08 35.3 0.0 0.051 13.9 0.0 5.0 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Hexokinase_2 PF03727.16 CAR29045.1 - 7.3e-79 264.6 0.0 9.4e-79 264.2 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CAR29045.1 - 2.1e-69 233.4 0.0 3.8e-69 232.6 0.0 1.4 1 0 0 1 1 1 1 Hexokinase GRASP55_65 PF04495.14 CAR29046.1 - 1.4e-36 125.8 0.0 7.3e-35 120.3 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain DEC-1_N PF04625.13 CAR29046.1 - 4.2 6.3 10.2 5.5 5.9 10.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Thioredoxin PF00085.20 CAR29047.1 - 3.4e-55 184.4 0.2 1.5e-28 98.8 0.0 4.0 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 CAR29047.1 - 3e-32 112.0 1.2 5.8e-23 81.8 0.6 3.4 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CAR29047.1 - 7.9e-09 35.3 0.0 0.0024 17.3 0.0 2.7 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CAR29047.1 - 2.5e-07 31.1 0.3 0.084 13.3 0.0 3.6 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CAR29047.1 - 3.6e-07 30.3 0.0 0.026 14.7 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CAR29047.1 - 6.6e-06 26.0 0.0 0.0015 18.5 0.0 2.7 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CAR29047.1 - 1.7e-05 25.1 0.2 0.19 12.1 0.0 3.5 3 1 0 3 3 3 2 Thioredoxin-like ERp29_N PF07912.13 CAR29047.1 - 0.00083 19.5 0.0 2.6 8.2 0.0 3.3 3 1 0 3 3 3 2 ERp29, N-terminal domain Redoxin PF08534.10 CAR29047.1 - 0.0068 16.1 0.0 4.2 7.1 0.0 2.4 2 0 0 2 2 2 2 Redoxin DBINO PF13892.6 CAR29047.1 - 0.098 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 DNA-binding domain Mgr1 PF08602.10 CAR29048.1 - 2.2e-174 579.9 0.6 3.1e-174 579.4 0.6 1.2 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit CCDC-167 PF15188.6 CAR29048.1 - 0.073 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 EMC1_C PF07774.13 CAR29049.1 - 1.7e-65 220.7 0.0 2.7e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CAR29049.1 - 0.001 18.7 0.0 0.33 10.5 0.0 2.6 2 1 0 2 2 2 2 PQQ-like domain PQQ PF01011.21 CAR29049.1 - 0.091 12.7 0.0 0.39 10.7 0.0 2.1 1 0 0 1 1 1 0 PQQ enzyme repeat FKBP_C PF00254.28 CAR29050.1 - 1e-33 115.5 0.0 1.2e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CTP_transf_like PF01467.26 CAR29051.1 - 1.1e-06 28.9 0.0 1.5e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 CAR29051.1 - 0.053 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP-sulfurylase Zn_clus PF00172.18 CAR29052.1 - 0.00024 21.1 5.4 0.00044 20.3 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Recep_L_domain PF01030.24 CAR29053.1 - 4.3e-09 36.5 11.9 0.00079 19.5 0.1 4.9 1 1 3 4 4 4 3 Receptor L domain LRR_9 PF14580.6 CAR29053.1 - 0.0062 16.1 0.6 0.012 15.2 0.6 1.6 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CAR29053.1 - 0.015 15.7 18.5 2.2 8.8 0.7 5.5 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) Rotavirus_VP1 PF12289.8 CAR29053.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Rotavirus VP1 C-terminal domain PTPS_related PF10131.9 CAR29053.1 - 0.12 10.7 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Pkinase PF00069.25 CAR29054.1 - 1.3e-65 221.4 0.0 1.9e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29054.1 - 1.4e-45 155.6 0.0 2e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR29054.1 - 3.3e-08 33.2 0.0 1.8e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CAR29054.1 - 0.0011 17.8 0.0 0.0019 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase ArfGap PF01412.18 CAR29055.1 - 4.7e-31 107.3 4.8 1.2e-30 106.0 4.8 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Asp_Glu_race PF01177.22 CAR29057.1 - 5.9e-11 42.6 0.0 1e-05 25.5 0.0 2.0 2 0 0 2 2 2 2 Asp/Glu/Hydantoin racemase RPAP1_C PF08620.10 CAR29058.1 - 8.1e-29 99.5 0.0 1.7e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CAR29058.1 - 1.1e-16 60.3 8.8 1.1e-16 60.3 8.8 2.3 2 0 0 2 2 2 1 RPAP1-like, N-terminal HEAT PF02985.22 CAR29058.1 - 0.018 15.2 1.4 0.14 12.5 0.0 3.0 3 1 0 3 3 3 0 HEAT repeat Kre28 PF17097.5 CAR29059.1 - 2.9e-140 467.4 27.9 3.3e-140 467.2 27.9 1.0 1 0 0 1 1 1 1 Spindle pole body component Bcr-Abl_Oligo PF09036.10 CAR29059.1 - 2.9 7.9 5.2 4.2 7.5 0.4 3.3 2 1 1 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Fumble PF03630.14 CAR29060.1 - 2.2e-127 424.8 0.9 3.1e-126 421.0 0.9 2.0 1 1 0 1 1 1 1 Fumble ATP_transf PF09830.9 CAR29061.1 - 1.5e-18 66.7 0.0 2.7e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 CAR29061.1 - 0.00046 19.6 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) DUF4922 PF16269.5 CAR29061.1 - 0.0034 17.2 0.0 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4922) HIT PF01230.23 CAR29061.1 - 0.079 13.7 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 HIT domain UCR_14kD PF02271.16 CAR29062.1 - 4.2e-39 132.6 0.1 4.9e-39 132.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit PIG-X PF08320.12 CAR29064.1 - 2e-27 96.5 0.0 3.1e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 Spb1_C PF07780.12 CAR29065.1 - 8.2e-86 287.0 20.2 8.2e-86 287.0 20.2 2.7 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 CAR29065.1 - 2.7e-53 180.7 0.1 2.7e-53 180.7 0.1 2.1 2 1 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CAR29065.1 - 7.4e-45 152.7 12.7 7.4e-45 152.7 12.7 5.0 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) ATP-synt_F6 PF05511.11 CAR29065.1 - 0.1 13.0 1.2 0.49 10.8 1.2 2.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Methyltransf_23 PF13489.6 CAR29065.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain AAA_30 PF13604.6 CAR29065.1 - 0.49 10.1 4.5 0.12 12.0 0.7 1.9 2 0 0 2 2 2 0 AAA domain MT-A70 PF05063.14 CAR29066.1 - 9.3e-11 41.9 0.1 1.4e-10 41.4 0.1 1.3 1 0 0 1 1 1 1 MT-A70 PEX11 PF05648.14 CAR29068.1 - 4.5e-06 26.3 0.6 6.4e-06 25.8 0.6 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_M3 PF01432.20 CAR29069.1 - 2.6e-145 485.2 1.3 3.8e-145 484.7 1.3 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF2250 PF10007.9 CAR29069.1 - 0.11 12.7 1.3 2 8.6 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) DUF543 PF04418.12 CAR29070.1 - 2.2e-32 110.9 0.1 2.5e-32 110.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) KH_8 PF17903.1 CAR29072.1 - 1.7e-31 108.1 0.1 4.5e-31 106.8 0.1 1.8 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CAR29072.1 - 0.045 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 KH domain MRC1 PF09444.10 CAR29073.1 - 4.9e-35 121.2 18.8 4.9e-35 121.2 18.8 6.8 4 2 4 8 8 8 1 MRC1-like domain Vac17 PF17321.2 CAR29074.1 - 1.5e-156 522.3 23.6 1.6e-156 522.2 23.6 1.0 1 0 0 1 1 1 1 Vacuole-related protein 17 Glyco_transf_10 PF00852.19 CAR29074.1 - 0.061 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term PALP PF00291.25 CAR29075.1 - 8.9e-59 199.3 0.0 1.1e-58 199.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4813 PF16072.5 CAR29076.1 - 0.0023 17.7 19.6 0.0027 17.4 19.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4813) Med3 PF11593.8 CAR29076.1 - 0.016 14.5 14.1 0.018 14.2 13.4 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Homeodomain PF00046.29 CAR29077.1 - 4.7e-07 29.6 0.2 1e-06 28.5 0.2 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CAR29077.1 - 2.7e-06 27.2 0.2 2.7e-06 27.2 0.2 2.1 2 1 0 2 2 2 1 Homeobox KN domain Syntaxin_2 PF14523.6 CAR29077.1 - 0.66 10.4 5.0 0.49 10.8 0.2 2.7 2 1 1 3 3 3 0 Syntaxin-like protein MATalpha_HMGbox PF04769.12 CAR29078.1 - 4.1e-11 42.6 0.3 7.8e-11 41.7 0.3 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box GMC_oxred_N PF00732.19 CAR29079.1 - 1.6e-54 185.3 0.0 2e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CAR29079.1 - 9.2e-30 104.1 0.0 1.4e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CAR29079.1 - 0.00093 18.4 0.2 0.91 8.5 0.8 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 CAR29079.1 - 0.004 16.4 0.5 0.0073 15.6 0.1 1.6 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 CAR29079.1 - 0.0087 15.3 0.2 0.61 9.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CAR29079.1 - 0.041 12.9 0.1 0.094 11.7 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CAR29079.1 - 0.39 9.9 2.2 0.74 9.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.21 CAR29080.1 - 3e-21 76.0 0.0 5.4e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAR29080.1 - 1.4e-12 47.7 0.0 6e-12 45.6 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CAR29080.1 - 3.5e-12 46.0 0.0 4.8e-06 25.9 0.0 2.4 2 1 1 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 CAR29080.1 - 8.2e-12 44.7 0.0 1.2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CAR29080.1 - 4.6e-07 29.3 0.0 4.7e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CAR29080.1 - 1.8e-06 28.0 0.0 2.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CAR29080.1 - 0.00013 21.4 0.0 0.00036 20.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 CAR29080.1 - 0.00044 19.9 0.0 0.0012 18.5 0.0 1.7 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 CAR29080.1 - 0.00078 19.4 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CAR29080.1 - 0.055 12.5 0.0 0.094 11.8 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain YAcAr PF10686.9 CAR29080.1 - 0.068 13.1 0.0 0.84 9.6 0.0 2.7 3 1 0 3 3 3 0 YspA, cpYpsA-related SLOG family Iron_permease PF04120.12 CAR29081.1 - 3.2e-30 104.6 22.6 2.2e-17 63.0 0.5 5.1 5 0 0 5 5 5 4 Low affinity iron permease DUP PF00674.18 CAR29082.1 - 6e-30 103.4 3.5 1.2e-15 57.5 0.3 2.3 2 0 0 2 2 2 2 DUP family AbiJ_NTD3 PF18860.1 CAR29082.1 - 0.079 12.5 0.1 1.3 8.6 0.0 2.6 2 1 1 3 3 3 0 AbiJ N-terminal domain 3 Sortilin-Vps10 PF15902.5 CAR29083.1 - 1.4e-47 162.6 0.0 3.2e-24 85.6 0.0 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CAR29083.1 - 2.4e-14 54.0 0.7 4.5e-14 53.2 0.7 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CAR29083.1 - 4.7e-11 41.0 19.2 0.34 11.1 0.3 8.3 8 0 0 8 8 8 6 BNR/Asp-box repeat PSII_BNR PF14870.6 CAR29083.1 - 0.00013 21.4 0.2 0.0018 17.6 0.0 2.7 3 1 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 DUP PF00674.18 CAR29084.1 - 3.4e-09 36.7 0.7 3.4e-09 36.7 0.7 2.3 2 0 0 2 2 2 1 DUP family MscS_TM PF12794.7 CAR29085.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 HD PF01966.22 CAR29086.1 - 2.2e-07 31.1 0.0 4.1e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 HD domain DUF5311 PF17238.2 CAR29087.1 - 0.038 13.9 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5311) BBE PF08031.12 CAR29087.1 - 0.085 13.0 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Berberine and berberine like Epimerase PF01370.21 CAR29088.1 - 6.1e-22 78.3 0.0 9.4e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAR29088.1 - 3.5e-14 53.0 0.0 6.3e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CAR29088.1 - 6.6e-14 51.7 0.0 4.5e-08 32.6 0.0 2.6 2 1 1 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 CAR29088.1 - 2.1e-13 49.9 0.0 3.1e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CAR29088.1 - 2.3e-08 34.1 0.0 3.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CAR29088.1 - 5.6e-07 29.0 0.0 3.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 CAR29088.1 - 1.5e-06 27.8 0.0 3.7e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 CAR29088.1 - 0.0007 19.2 0.0 0.004 16.7 0.1 2.2 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 CAR29088.1 - 0.006 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CAR29088.1 - 0.062 12.4 0.0 0.11 11.5 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Sugar_tr PF00083.24 CAR29089.1 - 2.2e-165 550.9 32.8 2.6e-165 550.7 32.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR29089.1 - 3.1e-27 95.5 32.2 4.5e-27 94.9 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 CAR29090.1 - 6e-17 61.6 1.5 1.2e-16 60.5 1.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR29090.1 - 0.00017 21.6 11.9 0.00036 20.6 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.14 CAR29091.1 - 1.1e-206 687.3 0.1 1.3e-206 687.0 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CAR29091.1 - 5.2e-99 331.2 0.3 9.5e-99 330.3 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CAR29091.1 - 6.2e-57 192.2 0.1 6.9e-55 185.5 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF615 PF04751.14 CAR29091.1 - 0.038 14.0 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF615) MFS_1 PF07690.16 CAR29092.1 - 1.9e-40 138.9 20.3 2.4e-40 138.6 20.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CAR29092.1 - 0.011 15.1 1.4 0.011 15.1 1.4 2.0 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Pox_G7 PF05503.12 CAR29092.1 - 0.032 13.2 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G7-like DUF4579 PF15158.6 CAR29092.1 - 6.3 6.5 6.9 5.6 6.7 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4579) Fungal_trans_2 PF11951.8 CAR29093.1 - 5.4e-47 160.4 6.4 7.6e-47 159.9 6.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR29093.1 - 9.1e-08 32.1 11.0 2.1e-07 31.0 11.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_4 PF01063.19 CAR29094.1 - 3.2e-36 125.3 0.0 4e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV 5-FTHF_cyc-lig PF01812.20 CAR29095.1 - 3.7e-43 147.6 0.0 4.2e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family SET PF00856.28 CAR29097.1 - 6.9e-16 59.1 0.0 2e-15 57.6 0.0 1.8 1 1 0 1 1 1 1 SET domain YacG PF03884.14 CAR29097.1 - 0.021 14.5 3.0 15 5.4 0.0 3.6 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Lar_restr_allev PF14354.6 CAR29097.1 - 0.49 10.8 6.2 0.33 11.4 2.4 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 CAR29097.1 - 1.3 9.1 7.0 1.6 8.8 2.8 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-FLZ PF04570.14 CAR29097.1 - 9.7 5.8 8.3 5.6 6.5 0.8 2.7 2 1 0 2 2 2 0 zinc-finger of the FCS-type, C2-C2 HSF_DNA-bind PF00447.17 CAR29098.1 - 3.8e-29 101.1 2.1 8.4e-29 100.0 2.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 CAR29098.1 - 2.8e-27 95.1 0.4 1e-26 93.3 0.4 2.0 2 0 0 2 2 2 1 Response regulator receiver domain NBP1 PF08537.10 CAR29098.1 - 0.018 14.5 3.0 0.034 13.6 3.0 1.5 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Pkinase PF00069.25 CAR29099.1 - 1.2e-67 228.1 0.0 1.9e-67 227.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29099.1 - 3e-31 108.7 0.0 4.7e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 CAR29099.1 - 4e-11 43.1 0.0 1.3e-06 28.6 0.0 2.7 2 0 0 2 2 2 2 C2 domain Pkinase_C PF00433.24 CAR29099.1 - 1.4e-09 38.5 1.7 1.4e-09 38.5 1.7 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 CAR29099.1 - 4.5e-09 36.0 0.0 9.4e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CAR29099.1 - 0.0018 17.3 3.0 0.0031 16.5 0.0 2.2 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 CAR29099.1 - 0.022 14.4 0.1 0.95 9.0 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 CAR29099.1 - 0.043 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pr_beta_C PF12465.8 CAR29099.1 - 0.072 12.5 0.7 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 Proteasome beta subunits C terminal Glyco_hydro_47 PF01532.20 CAR29100.1 - 5.4e-113 378.3 0.0 7e-113 377.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2593 PF10767.9 CAR29100.1 - 0.038 14.1 0.1 0.07 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) Ribosomal_S4e PF00900.20 CAR29101.1 - 3.7e-38 129.3 0.7 4.2e-37 125.9 0.5 2.2 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CAR29101.1 - 1.4e-25 88.6 0.1 2.9e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CAR29101.1 - 6e-20 71.1 7.0 1.6e-19 69.7 7.0 1.8 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 CAR29101.1 - 1.7e-09 37.3 0.3 3.7e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 CAR29101.1 - 4.9e-06 26.3 2.1 4.9e-06 26.3 2.1 3.2 4 0 0 4 4 4 1 KOW motif Metallophos PF00149.28 CAR29102.1 - 2.3e-11 44.6 2.3 4e-11 43.8 2.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 CAR29102.1 - 0.011 16.0 0.0 0.38 11.0 0.0 2.3 1 1 1 2 2 2 0 5'-nucleotidase, C-terminal domain Type_ISP_C PF18135.1 CAR29102.1 - 0.029 13.4 0.1 0.059 12.4 0.0 1.6 2 0 0 2 2 2 0 Type ISP C-terminal specificity domain DSPn PF14671.6 CAR29103.1 - 1.1e-45 155.5 0.0 4.2e-45 153.7 0.0 1.9 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CAR29103.1 - 5.5e-25 87.7 0.0 8.9e-24 83.8 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR29103.1 - 0.00015 21.5 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CAR29103.1 - 0.00085 19.0 0.1 0.0017 18.1 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CAR29103.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Acetyltransf_13 PF13880.6 CAR29104.1 - 7.6e-22 77.1 0.2 1.9e-21 75.8 0.2 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 CAR29104.1 - 2e-11 43.5 0.3 3.4e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 CAR29104.1 - 0.00041 20.6 0.0 0.00086 19.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CAR29104.1 - 0.0018 18.7 0.0 0.006 17.0 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CAR29104.1 - 0.094 12.7 0.0 0.5 10.3 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-met PF12874.7 CAR29104.1 - 0.6 10.6 4.9 3.6 8.1 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PHP PF02811.19 CAR29105.1 - 2.3e-12 47.5 1.1 2.3e-12 47.5 1.1 1.6 2 1 0 2 2 2 1 PHP domain ProRS-C_1 PF09180.11 CAR29106.1 - 2.1e-25 88.7 1.2 3.8e-25 87.9 1.2 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CAR29106.1 - 4.6e-19 68.4 0.0 9.4e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CAR29106.1 - 1.6e-15 57.5 0.0 3.2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 CAR29106.1 - 0.0038 17.3 0.1 0.0078 16.3 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain MtrG PF04210.13 CAR29106.1 - 0.2 11.5 0.8 0.51 10.2 0.1 2.0 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G tRNA-synt_2 PF00152.20 CAR29107.1 - 2.1e-91 306.3 0.0 3.3e-91 305.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAR29107.1 - 4.4e-13 49.0 0.0 9.3e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.11 CAR29107.1 - 0.036 13.6 0.0 0.077 12.5 0.0 1.6 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Lyase_1 PF00206.20 CAR29108.1 - 1.6e-97 326.7 0.0 2.4e-97 326.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 CAR29108.1 - 1.1e-21 77.3 0.0 2.6e-21 76.2 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1776 PF08643.10 CAR29109.1 - 8.3e-50 169.8 0.2 1.4e-49 169.1 0.2 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Ysc84 PF04366.12 CAR29110.1 - 2.4e-45 153.4 0.3 4.8e-45 152.4 0.3 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CAR29110.1 - 4.6e-15 54.9 0.1 8.9e-15 54.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR29110.1 - 3.1e-12 46.2 0.1 6.3e-12 45.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR29110.1 - 1.5e-11 43.7 0.1 1.5e-11 43.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain RRM_1 PF00076.22 CAR29111.1 - 3e-43 145.5 5.9 8.9e-15 54.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR29111.1 - 0.0029 17.6 0.3 0.43 10.6 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CAR29111.1 - 0.013 15.0 0.5 0.17 11.5 0.1 2.8 2 1 1 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR29111.1 - 0.059 13.5 0.1 13 6.0 0.0 3.9 5 0 0 5 5 5 0 RNA recognition motif Pyr_redox_2 PF07992.14 CAR29112.1 - 1.7e-45 155.5 0.0 1.5e-44 152.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CAR29112.1 - 1.2e-14 54.6 0.1 2.1e-10 41.0 0.0 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CAR29112.1 - 0.39 9.9 1.4 10 5.2 1.8 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAP PF00956.18 CAR29113.1 - 0.0026 17.0 2.8 0.11 11.7 0.9 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Dynein_attach_N PF15867.5 CAR29113.1 - 0.093 12.7 0.1 6.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Dynein attachment factor N-terminus Arrestin_C PF02752.22 CAR29114.1 - 8.2e-24 84.6 0.0 4.8e-23 82.1 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CAR29114.1 - 3.8e-09 36.7 0.0 2.9e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CAR29114.1 - 0.005 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin_N terminal like ANAPC4_WD40 PF12894.7 CAR29115.1 - 6.1e-08 32.9 0.0 0.014 15.7 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR29115.1 - 1.6e-06 28.7 0.0 0.17 12.8 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CAR29115.1 - 0.043 12.8 0.4 0.63 8.9 0.0 2.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PIP5K PF01504.18 CAR29116.1 - 3.9e-41 141.1 2.2 7.3e-36 123.8 0.7 4.9 5 1 1 6 6 6 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CAR29116.1 - 3.9e-27 95.0 0.0 6.5e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CAR29116.1 - 2.1e-17 63.0 10.8 2.1e-17 63.0 10.8 1.9 2 0 0 2 2 2 1 FYVE zinc finger DUF3391 PF11871.8 CAR29116.1 - 1.7 9.2 7.9 0.13 12.8 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) IBR PF01485.21 CAR29116.1 - 1.8 8.8 7.8 0.84 9.9 4.0 2.3 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain FYVE_2 PF02318.16 CAR29116.1 - 3.6 7.8 10.3 0.97 9.7 5.2 2.6 2 0 0 2 2 2 0 FYVE-type zinc finger DZR PF12773.7 CAR29116.1 - 7.7 6.6 11.4 1.6e+02 2.4 0.0 3.2 2 1 0 2 2 2 0 Double zinc ribbon Peptidase_M28 PF04389.17 CAR29117.1 - 4.2e-41 140.8 0.0 5.3e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 RibD_C PF01872.17 CAR29117.1 - 0.075 12.8 0.0 0.17 11.7 0.0 1.5 2 0 0 2 2 2 0 RibD C-terminal domain TIP120 PF08623.10 CAR29118.1 - 0.00012 21.8 0.0 0.0013 18.5 0.0 2.6 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Cnd1 PF12717.7 CAR29118.1 - 0.024 14.7 0.1 0.6 10.1 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF1878 PF08963.10 CAR29118.1 - 0.029 14.9 0.1 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1878) GTP_EFTU PF00009.27 CAR29120.1 - 2.3e-31 108.9 11.4 1.3e-28 99.8 6.3 3.2 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CAR29120.1 - 5.3e-27 94.0 0.5 1.5e-26 92.5 0.5 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 CAR29120.1 - 6.1e-09 35.6 0.0 1.8e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 CAR29120.1 - 1.2e-08 35.1 3.0 1.7e-08 34.5 0.8 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CAR29120.1 - 4.5e-05 23.8 2.6 0.0006 20.1 0.1 3.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 CAR29120.1 - 6.9e-05 22.8 3.9 0.0048 16.8 0.6 2.6 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CAR29120.1 - 0.0011 18.4 0.1 0.0024 17.3 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CAR29120.1 - 0.002 18.2 0.9 1.7 8.7 0.1 3.4 2 1 1 3 3 3 2 Dynamin family Ras PF00071.22 CAR29120.1 - 0.0048 16.5 0.1 0.0096 15.5 0.1 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR29120.1 - 0.011 16.0 0.2 0.022 15.0 0.2 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CAR29120.1 - 0.02 14.4 1.6 0.067 12.7 0.4 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 CAR29120.1 - 0.037 13.8 1.0 0.19 11.5 1.0 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 CAR29120.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PDCD2_C PF04194.13 CAR29121.1 - 4.4e-41 140.9 1.1 2.8e-39 135.0 0.0 3.0 3 0 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain ABC_tran PF00005.27 CAR29122.1 - 4.1e-46 156.9 1.4 1.1e-21 77.8 0.2 3.2 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CAR29122.1 - 2.8e-19 68.9 8.5 2.8e-19 68.9 8.5 3.0 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.6 CAR29122.1 - 3.2e-17 63.3 15.7 2.6e-05 24.2 0.0 5.6 5 1 1 6 6 6 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR29122.1 - 4.5e-11 42.6 0.2 0.00072 19.1 0.3 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CAR29122.1 - 1.5e-07 31.9 0.4 0.0026 18.2 0.3 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CAR29122.1 - 3.2e-07 30.0 0.1 0.04 13.7 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 CAR29122.1 - 1.6e-06 28.5 1.5 0.041 14.1 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.6 CAR29122.1 - 8.2e-06 26.1 1.2 0.22 11.8 0.0 3.5 3 1 0 3 3 2 2 AAA domain NACHT PF05729.12 CAR29122.1 - 1.9e-05 24.6 0.3 0.086 12.8 0.1 2.6 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 CAR29122.1 - 2.5e-05 24.3 0.0 0.045 13.6 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 CAR29122.1 - 2.9e-05 24.1 0.1 0.45 10.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 CAR29122.1 - 3.1e-05 24.4 0.2 0.17 12.3 0.0 3.7 4 1 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 CAR29122.1 - 5.3e-05 23.1 17.1 0.014 15.1 0.0 4.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_24 PF13479.6 CAR29122.1 - 7.3e-05 22.6 0.0 0.3 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CAR29122.1 - 9.6e-05 22.4 0.0 0.15 12.2 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 CAR29122.1 - 0.00011 22.7 26.9 0.15 12.5 0.0 5.2 5 0 0 5 5 5 2 AAA domain RNA_helicase PF00910.22 CAR29122.1 - 0.00012 22.4 0.8 0.91 9.9 0.0 3.7 4 0 0 4 4 3 1 RNA helicase AAA_33 PF13671.6 CAR29122.1 - 0.00023 21.3 1.7 0.41 10.8 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_30 PF13604.6 CAR29122.1 - 0.00028 20.7 0.0 0.28 10.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 CAR29122.1 - 0.00038 21.0 5.5 0.3 11.6 0.1 4.0 5 0 0 5 5 3 2 AAA domain PduV-EutP PF10662.9 CAR29122.1 - 0.00042 20.1 0.8 0.65 9.7 0.1 3.0 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.25 CAR29122.1 - 0.00059 19.5 0.0 0.07 12.8 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 CAR29122.1 - 0.00073 19.5 1.6 4.4 7.3 0.1 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CAR29122.1 - 0.00085 18.9 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Roc PF08477.13 CAR29122.1 - 0.0014 18.8 0.1 2 8.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CAR29122.1 - 0.0021 17.3 0.5 1.1 8.4 0.0 2.7 2 1 0 2 2 2 1 NB-ARC domain MeaB PF03308.16 CAR29122.1 - 0.0046 16.0 0.0 0.38 9.7 0.0 2.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 CAR29122.1 - 0.0054 15.9 1.8 1.3 8.1 0.0 2.7 3 0 0 3 3 3 1 G-protein alpha subunit TsaE PF02367.17 CAR29122.1 - 0.006 16.6 0.0 0.61 10.1 0.0 2.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 CAR29122.1 - 0.0074 15.5 0.1 2 7.5 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 CAR29122.1 - 0.0086 15.7 0.2 1.8 8.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 CAR29122.1 - 0.0092 15.5 1.1 0.79 9.1 0.0 3.0 3 0 0 3 3 3 1 Poxvirus A32 protein Zeta_toxin PF06414.12 CAR29122.1 - 0.01 15.2 0.4 2.4 7.4 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin Septin PF00735.18 CAR29122.1 - 0.012 14.9 0.9 2 7.6 0.2 2.7 2 1 0 2 2 2 0 Septin FeoB_N PF02421.18 CAR29122.1 - 0.016 14.7 0.0 6.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B ATPase_2 PF01637.18 CAR29122.1 - 0.018 15.0 2.0 2.2 8.1 0.0 3.1 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CAR29122.1 - 0.021 14.7 0.0 3.5 7.5 0.0 2.7 2 0 0 2 2 2 0 NTPase MobB PF03205.14 CAR29122.1 - 0.021 14.7 0.3 0.83 9.6 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 CAR29122.1 - 0.029 14.3 0.1 2.2 8.2 0.0 2.7 2 1 1 3 3 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 CAR29122.1 - 0.038 13.4 0.3 4.2 6.7 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.22 CAR29122.1 - 0.047 13.3 0.3 2.9 7.5 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 CAR29122.1 - 0.053 13.1 0.2 9.3 5.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 CAR29122.1 - 0.074 13.3 0.0 38 4.6 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Ras PF00071.22 CAR29122.1 - 0.12 12.0 1.3 18 4.9 0.1 3.0 3 0 0 3 3 3 0 Ras family Viral_helicase1 PF01443.18 CAR29122.1 - 0.13 12.0 0.0 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.23 CAR29122.1 - 0.15 12.1 8.6 1.7 8.7 5.4 3.4 3 1 0 3 3 2 0 Dynamin family DUF2813 PF11398.8 CAR29122.1 - 0.55 9.4 8.5 0.81 8.9 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2813) Med4 PF10018.9 CAR29122.1 - 5.6 6.6 8.8 0.76 9.4 4.1 2.0 2 0 0 2 2 1 0 Vitamin-D-receptor interacting Mediator subunit 4 RNB PF00773.19 CAR29123.1 - 1.5e-96 323.5 0.0 3.1e-96 322.6 0.0 1.5 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 CAR29123.1 - 4.8e-73 243.7 0.2 1.1e-72 242.6 0.2 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CAR29123.1 - 1.1e-29 102.2 1.6 3.5e-29 100.6 1.6 1.9 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 CAR29123.1 - 2.7e-18 65.7 0.0 6.8e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 CAR29123.1 - 9.8e-15 55.0 0.2 2.5e-14 53.7 0.2 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 CAR29123.1 - 1.9e-05 24.8 0.0 0.028 14.6 0.0 3.1 2 0 0 2 2 2 2 Cold shock domain Dis3l2_C_term PF17877.1 CAR29123.1 - 0.0087 16.4 0.3 0.024 15.0 0.3 1.7 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 CAR29123.1 - 0.036 13.7 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain PIN_12 PF16289.5 CAR29123.1 - 0.064 13.8 1.2 0.28 11.7 1.2 2.2 1 1 0 1 1 1 0 PIN domain PIN PF01850.21 CAR29123.1 - 0.12 12.9 0.1 0.41 11.2 0.1 2.1 1 0 0 1 1 1 0 PIN domain UCH PF00443.29 CAR29124.1 - 1.9e-51 175.1 5.2 2.3e-51 174.7 5.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR29124.1 - 3.3e-13 49.9 16.1 1e-11 45.0 16.1 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CAR29124.1 - 3.9e-06 26.5 0.0 3.5e-05 23.5 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin family SPDY PF03771.16 CAR29124.1 - 0.049 13.6 0.1 0.11 12.4 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF317) PTAC PF06130.12 CAR29124.1 - 0.075 13.2 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 Phosphate propanoyltransferase DUF1690 PF07956.11 CAR29125.1 - 8.3e-42 142.9 10.8 9.5e-42 142.7 10.8 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF4240 PF14024.6 CAR29125.1 - 0.064 13.4 0.5 0.16 12.2 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4240) DNA_meth_N PF18284.1 CAR29125.1 - 0.1 12.5 0.4 0.23 11.4 0.4 1.6 1 0 0 1 1 1 0 DNA methylase N-terminal domain ARD PF03079.14 CAR29126.1 - 3e-41 141.2 0.2 3.5e-41 141.0 0.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CAR29126.1 - 2e-08 33.8 0.0 3.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CAR29126.1 - 4.6e-05 23.3 0.0 8.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain dTDP_sugar_isom PF00908.17 CAR29126.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase PQ-loop PF04193.14 CAR29127.1 - 1.1e-13 50.8 9.4 7.9e-11 41.6 4.7 3.1 2 0 0 2 2 2 2 PQ loop repeat Pet127 PF08634.10 CAR29128.1 - 1.7e-99 332.7 6.1 2.3e-98 329.0 6.1 2.4 1 1 0 1 1 1 1 Mitochondrial protein Pet127 EDR1 PF14381.6 CAR29128.1 - 0.0085 15.8 0.0 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 Ethylene-responsive protein kinase Le-CTR1 TauD PF02668.16 CAR29129.1 - 8.2e-48 163.5 0.1 1.2e-47 162.9 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CAR29129.1 - 0.00023 21.7 0.0 0.0018 18.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF971) CsiD PF08943.10 CAR29129.1 - 0.021 13.9 0.1 0.28 10.3 0.0 2.1 2 0 0 2 2 2 0 CsiD Ribonuc_red_lgC PF02867.15 CAR29129.1 - 0.098 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain TP6A_N PF04406.14 CAR29130.1 - 6.5e-18 64.5 0.9 2.7e-17 62.5 0.9 2.2 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF4825 PF16107.5 CAR29130.1 - 0.026 14.7 0.0 0.08 13.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4825) Pan_kinase PF03309.14 CAR29130.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Type III pantothenate kinase EMP24_GP25L PF01105.24 CAR29131.1 - 6.9e-37 127.2 0.0 8e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FUN14 PF04930.15 CAR29132.1 - 1.5e-06 28.5 1.3 4.2e-06 27.1 1.3 1.8 1 1 0 1 1 1 1 FUN14 family TMEM108 PF15759.5 CAR29132.1 - 0.021 13.9 0.1 0.026 13.6 0.1 1.0 1 0 0 1 1 1 0 TMEM108 family B56 PF01603.20 CAR29133.1 - 2.5e-173 576.8 10.5 3.6e-173 576.3 10.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Acetyltransf_10 PF13673.7 CAR29134.1 - 0.13 12.2 0.0 0.31 11.0 0.1 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.6 CAR29135.1 - 2.8e-72 243.9 42.9 3.5e-72 243.5 42.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAR29135.1 - 6.9e-24 84.3 31.6 1.1e-23 83.6 31.6 1.3 1 0 0 1 1 1 1 Amino acid permease Spo7 PF03907.13 CAR29136.1 - 2.5e-72 242.9 7.4 4.3e-72 242.2 7.4 1.3 1 0 0 1 1 1 1 Spo7-like protein MDM10 PF12519.8 CAR29137.1 - 1.2e-148 495.9 17.5 1.3e-148 495.8 17.5 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 AAA_23 PF13476.6 CAR29139.1 - 7.3e-22 78.9 9.3 7.3e-22 78.9 9.3 6.1 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.19 CAR29139.1 - 7.7e-14 51.7 48.3 6e-13 48.7 48.3 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CAR29139.1 - 1.4e-10 41.5 26.3 1.4e-10 41.5 26.3 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CAR29139.1 - 6.9e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 CAR29139.1 - 0.0036 16.9 0.0 0.024 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CAR29139.1 - 0.015 15.2 0.1 0.015 15.2 0.1 4.1 4 1 1 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system UCH PF00443.29 CAR29140.1 - 1.6e-53 181.8 1.9 3e-53 180.9 1.9 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 CAR29140.1 - 3e-45 152.0 7.8 1.1e-18 66.9 0.1 5.1 5 0 0 5 5 5 4 A repeated domain in UCH-protein UCH_1 PF13423.6 CAR29140.1 - 0.0029 17.2 7.6 0.045 13.3 1.6 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EF-hand_1 PF00036.32 CAR29141.1 - 3.6e-26 88.7 5.0 1.4e-07 30.6 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CAR29141.1 - 5.6e-24 82.0 4.2 2.8e-06 26.8 0.1 4.8 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 CAR29141.1 - 1.3e-23 83.2 7.2 5.9e-17 61.9 0.7 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 CAR29141.1 - 1e-18 65.9 6.3 3.4e-05 23.1 0.2 4.3 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CAR29141.1 - 1.9e-17 62.8 7.4 2.9e-08 33.4 0.1 3.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 CAR29141.1 - 0.00019 21.7 0.2 0.0075 16.6 0.1 2.5 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 CAR29141.1 - 0.00037 20.4 4.2 1.3 9.0 0.2 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CAR29141.1 - 0.00079 19.7 0.7 0.11 12.9 0.6 3.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.15 CAR29141.1 - 0.028 14.5 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain YxiJ PF14176.6 CAR29141.1 - 0.063 13.8 0.2 0.11 13.0 0.2 1.5 1 1 0 1 1 1 0 YxiJ-like protein COQ7 PF03232.13 CAR29142.1 - 1e-73 246.7 0.1 1.2e-73 246.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 CAR29142.1 - 0.013 15.8 0.3 0.071 13.5 0.0 2.1 2 1 0 2 2 2 0 Rubrerythrin YTH PF04146.15 CAR29143.1 - 1.2e-32 113.2 1.1 5.7e-32 110.9 1.1 2.0 1 1 0 1 1 1 1 YT521-B-like domain BCS1_N PF08740.11 CAR29145.1 - 2e-46 158.4 0.1 2.7e-46 157.9 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CAR29145.1 - 7.3e-23 81.4 0.0 1.4e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAR29145.1 - 0.002 18.5 0.0 0.0058 17.0 0.0 1.8 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 CAR29145.1 - 0.003 17.3 0.0 0.006 16.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CAR29145.1 - 0.0042 16.6 0.0 0.019 14.5 0.0 2.1 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 CAR29145.1 - 0.0055 17.2 0.0 0.023 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CAR29145.1 - 0.0082 15.9 0.0 0.024 14.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 CAR29145.1 - 0.0099 15.9 0.0 0.024 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CAR29145.1 - 0.012 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CAR29145.1 - 0.018 15.0 0.0 0.32 10.9 0.0 2.7 2 1 1 3 3 3 0 NACHT domain ABC_tran PF00005.27 CAR29145.1 - 0.023 15.2 0.0 0.044 14.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CAR29145.1 - 0.025 14.3 0.0 0.065 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.13 CAR29145.1 - 0.028 13.6 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_21 PF13304.6 CAR29145.1 - 0.046 13.5 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 CAR29145.1 - 0.047 14.1 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 CAR29145.1 - 0.061 13.6 0.0 0.17 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CAR29145.1 - 0.071 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 CAR29145.1 - 0.11 12.4 0.0 0.73 9.7 0.0 2.0 1 1 1 2 2 2 0 Rad17 P-loop domain Gram_pos_anchor PF00746.21 CAR29145.1 - 0.12 12.3 0.4 0.34 10.9 0.4 1.7 1 0 0 1 1 1 0 LPXTG cell wall anchor motif TIP49 PF06068.13 CAR29145.1 - 0.13 11.5 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_23 PF13476.6 CAR29145.1 - 0.18 12.3 0.0 0.56 10.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 CAR29145.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Lipase_GDSL_2 PF13472.6 CAR29146.1 - 1.8e-22 80.6 0.0 3.5e-22 79.6 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CAR29146.1 - 2.2e-12 47.4 0.0 3.9e-12 46.6 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pyr_redox_2 PF07992.14 CAR29147.1 - 2.3e-07 30.4 0.0 6.2e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CAR29147.1 - 0.00015 22.0 0.0 0.00035 20.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CAR29147.1 - 0.0036 17.3 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 CAR29147.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 CAR29147.1 - 0.17 11.9 0.0 21 5.2 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase F1F0-ATPsyn_F PF10791.9 CAR29148.1 - 2e-42 143.6 0.1 2.3e-42 143.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi LSM PF01423.22 CAR29149.1 - 2.2e-16 59.3 0.0 2.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAR29149.1 - 0.00032 20.8 0.0 0.0023 18.0 0.0 2.0 1 1 1 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.7 CAR29149.1 - 0.029 14.5 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain LicD PF04991.13 CAR29150.1 - 2.5e-46 158.7 3.2 2.5e-46 158.7 3.2 2.2 3 0 0 3 3 3 1 LicD family CN_hydrolase PF00795.22 CAR29151.1 - 6.3e-18 65.0 0.0 2.3e-16 59.9 0.0 2.5 3 0 0 3 3 3 2 Carbon-nitrogen hydrolase PRCC PF10253.9 CAR29152.1 - 0.096 13.5 11.4 0.47 11.2 11.4 1.9 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting TFIIS_C PF01096.18 CAR29153.1 - 1.2e-18 66.7 1.2 1.2e-18 66.7 1.2 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CAR29153.1 - 8.5e-13 47.9 9.7 2.6e-10 40.0 0.7 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 CAR29153.1 - 3.5e-05 23.8 7.5 0.013 15.6 0.3 2.8 2 1 0 2 2 2 2 Double zinc ribbon TF_Zn_Ribbon PF08271.12 CAR29153.1 - 0.00012 21.5 5.8 0.013 15.0 2.0 2.7 2 1 0 2 2 2 2 TFIIB zinc-binding Baculo_LEF5_C PF11792.8 CAR29153.1 - 0.0041 16.8 1.4 0.021 14.5 1.4 2.2 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_4 PF13717.6 CAR29153.1 - 0.0077 16.1 11.4 0.93 9.5 0.8 3.5 3 0 0 3 3 3 2 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.7 CAR29153.1 - 0.013 15.5 4.7 0.023 14.7 0.9 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C4_Topoisom PF01396.19 CAR29153.1 - 0.014 15.2 6.8 0.021 14.6 2.2 3.1 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-TFIIB PF13453.6 CAR29153.1 - 0.017 14.4 0.8 0.017 14.4 0.8 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger DpnI PF06044.12 CAR29153.1 - 0.031 13.9 2.1 2.6 7.7 0.1 2.1 2 0 0 2 2 2 0 Dam-replacing family Lar_restr_allev PF14354.6 CAR29153.1 - 0.041 14.2 7.8 0.31 11.4 0.8 3.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar C1_1 PF00130.22 CAR29153.1 - 0.043 13.7 4.6 0.49 10.3 0.2 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Elf1 PF05129.13 CAR29153.1 - 0.046 13.8 4.1 0.58 10.2 0.6 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Ogr_Delta PF04606.12 CAR29153.1 - 0.059 13.4 3.1 0.059 13.4 3.1 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger TackOD1 PF18551.1 CAR29153.1 - 0.063 12.9 6.1 0.59 9.8 0.3 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc_ribbon_2 PF13240.6 CAR29153.1 - 0.078 12.7 13.1 1 9.2 0.4 3.9 3 1 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 CAR29153.1 - 0.084 12.9 6.9 1.2 9.1 4.9 2.8 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Baculo_p48 PF04878.13 CAR29153.1 - 0.089 11.7 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Baculovirus P48 protein Zn_Tnp_IS91 PF14319.6 CAR29153.1 - 0.11 12.6 7.3 5.9 7.0 3.2 3.0 2 1 0 2 2 2 0 Transposase zinc-binding domain GATA PF00320.27 CAR29153.1 - 0.12 12.0 0.3 0.12 12.0 0.3 2.8 3 1 0 3 3 3 0 GATA zinc finger zf-H2C2_2 PF13465.6 CAR29153.1 - 0.13 12.8 4.5 1.5 9.3 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 CAR29153.1 - 0.16 12.1 12.6 4 7.6 0.7 3.4 3 0 0 3 3 3 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 CAR29153.1 - 0.25 11.3 8.3 6 6.9 2.9 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Stc1 PF12898.7 CAR29153.1 - 0.3 11.7 6.8 0.27 11.8 1.1 2.4 1 1 1 2 2 2 0 Stc1 domain Rubredoxin PF00301.20 CAR29153.1 - 0.42 10.7 7.6 5.2 7.2 0.9 3.3 3 0 0 3 3 3 0 Rubredoxin zinc-ribbons_6 PF07191.12 CAR29153.1 - 0.76 9.8 10.0 5.7 7.0 1.9 2.8 2 2 0 2 2 2 0 zinc-ribbons CpXC PF14353.6 CAR29153.1 - 0.97 9.5 8.0 16 5.6 5.3 3.1 1 1 2 3 3 3 0 CpXC protein zf-piccolo PF05715.13 CAR29153.1 - 2.1 8.5 7.4 2.3 8.4 0.4 2.7 2 1 0 2 2 2 0 Piccolo Zn-finger zf-ribbon_3 PF13248.6 CAR29153.1 - 3.2 7.3 13.7 0.94 9.0 0.5 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 CAR29153.1 - 5.4 7.8 9.7 5.3e+02 1.5 10.1 2.9 1 1 1 2 2 2 0 zinc-ribbon family LRV_FeS PF05484.11 CAR29153.1 - 6.9 6.8 9.2 6 6.9 0.1 3.3 4 0 0 4 4 3 0 LRV protein FeS4 cluster Zn_ribbon_SprT PF17283.2 CAR29153.1 - 7.2 6.6 14.4 9.5 6.2 3.5 3.4 3 1 0 3 3 3 0 SprT-like zinc ribbon domain DUF983 PF06170.12 CAR29153.1 - 7.8 7.0 7.7 42 4.6 4.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF983) Cpn60_TCP1 PF00118.24 CAR29154.1 - 4.9e-153 510.3 4.4 5.6e-153 510.1 4.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Actin PF00022.19 CAR29155.1 - 2.1e-90 303.3 0.0 7.6e-54 182.9 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 CAR29155.1 - 2.7e-06 26.4 0.0 0.0013 17.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CAR29155.1 - 0.00013 22.3 0.1 0.0012 19.3 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA FAT PF02259.23 CAR29156.1 - 7.3e-142 472.7 0.2 3.4e-141 470.5 0.0 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 CAR29156.1 - 2.8e-73 246.8 0.0 5.5e-73 245.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CAR29156.1 - 6.6e-69 230.9 17.0 8.4e-66 220.8 0.5 6.0 5 1 0 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CAR29156.1 - 1.3e-42 144.2 2.6 6.6e-42 141.9 0.3 2.9 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 CAR29156.1 - 2.6e-18 65.5 0.4 7.3e-18 64.1 0.4 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 CAR29156.1 - 1.2e-13 51.2 8.2 0.26 11.7 0.0 8.3 7 2 1 8 8 8 4 HEAT repeats HEAT_EZ PF13513.6 CAR29156.1 - 5.9e-09 36.2 3.1 0.0021 18.5 0.0 8.4 8 1 1 9 9 8 1 HEAT-like repeat HEAT PF02985.22 CAR29156.1 - 1.3e-07 31.2 0.8 0.027 14.7 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat DUF3437 PF11919.8 CAR29156.1 - 0.00034 20.5 0.0 2.3 8.2 0.0 4.3 4 0 0 4 4 4 2 Domain of unknown function (DUF3437) Vac14_Fab1_bd PF12755.7 CAR29156.1 - 0.17 12.5 5.9 19 6.0 0.0 5.2 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region MMS19_N PF14500.6 CAR29156.1 - 0.31 10.6 3.5 2.1 7.8 0.2 3.7 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II TPR_12 PF13424.6 CAR29156.1 - 0.43 10.9 2.1 56 4.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Yae1_N PF09811.9 CAR29157.1 - 1.1e-12 47.4 0.1 1.6e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Rep_fac_C PF08542.11 CAR29158.1 - 1.9e-17 63.5 0.0 4.5e-17 62.2 0.0 1.7 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 CAR29158.1 - 6.2e-16 59.0 0.0 2.9e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CAR29158.1 - 3.7e-13 49.6 0.0 1.8e-12 47.3 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CAR29158.1 - 8.9e-08 32.3 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 CAR29158.1 - 1.2e-05 25.6 0.0 9.2e-05 22.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAR29158.1 - 5.5e-05 23.6 0.1 0.0094 16.4 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CAR29158.1 - 7.4e-05 22.5 0.0 0.00017 21.4 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 CAR29158.1 - 7.7e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 CAR29158.1 - 0.00011 22.1 0.0 0.00031 20.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CAR29158.1 - 0.00015 21.8 0.0 0.00038 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CAR29158.1 - 0.00021 20.7 0.0 0.0084 15.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 CAR29158.1 - 0.00062 19.5 0.0 0.0019 17.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CAR29158.1 - 0.0015 19.0 0.0 0.0028 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CAR29158.1 - 0.002 17.9 0.0 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 CAR29158.1 - 0.0039 17.0 0.0 0.011 15.6 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DNA_pol3_gamma3 PF12169.8 CAR29158.1 - 0.0041 17.0 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III subunits gamma and tau domain III AAA_7 PF12775.7 CAR29158.1 - 0.0058 16.2 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 CAR29158.1 - 0.0058 17.0 0.0 0.037 14.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CAR29158.1 - 0.0072 15.6 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 CAR29158.1 - 0.0084 15.3 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 CAR29158.1 - 0.012 15.6 0.0 0.071 13.1 0.0 2.1 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 CAR29158.1 - 0.013 16.0 0.0 0.069 13.7 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 CAR29158.1 - 0.019 15.0 0.2 0.083 12.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CAR29158.1 - 0.034 14.0 0.0 0.25 11.2 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CAR29158.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 CAR29158.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Xpo1 PF08389.12 CAR29160.1 - 3.9e-36 124.3 1.1 3.9e-36 124.3 1.1 4.1 4 0 0 4 4 4 1 Exportin 1-like protein ATP-gua_PtransN PF02807.15 CAR29160.1 - 0.00032 21.0 0.0 0.36 11.3 0.0 2.9 2 0 0 2 2 2 2 ATP:guanido phosphotransferase, N-terminal domain Ham1p_like PF01725.16 CAR29161.1 - 3.6e-50 170.5 0.0 4e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family HEAT_2 PF13646.6 CAR29162.1 - 2e-28 98.6 0.3 1.1e-13 51.3 0.0 3.0 2 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 CAR29162.1 - 1.4e-17 62.5 0.0 0.0002 21.8 0.0 6.1 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT PF02985.22 CAR29162.1 - 1.3e-10 40.6 0.6 0.23 11.8 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 CAR29162.1 - 1.6e-05 25.3 2.0 6.7 7.3 0.1 5.1 4 2 1 5 5 5 2 HEAT-like repeat Arm PF00514.23 CAR29162.1 - 0.00058 19.8 0.0 0.076 13.1 0.0 2.6 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 CAR29162.1 - 0.0076 16.5 0.1 2 8.8 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion DUF4535 PF15054.6 CAR29162.1 - 0.012 15.3 0.1 0.034 13.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) NblA PF04485.12 CAR29162.1 - 0.15 12.5 3.6 0.89 10.0 0.2 2.9 3 0 0 3 3 3 0 Phycobilisome degradation protein nblA PAC2 PF09754.9 CAR29163.1 - 2.4e-27 96.3 0.0 4e-27 95.6 0.0 1.4 1 1 0 1 1 1 1 PAC2 family ATP_bind_1 PF03029.17 CAR29164.1 - 3.5e-79 266.0 0.0 6.2e-79 265.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CAR29164.1 - 4.8e-06 26.2 0.0 0.00025 20.6 0.0 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAR29164.1 - 0.00019 21.5 0.0 0.0045 17.1 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CAR29164.1 - 0.00043 20.5 0.0 0.00098 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 CAR29164.1 - 0.00063 19.6 0.1 0.62 9.8 0.0 2.7 3 0 0 3 3 3 2 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 CAR29164.1 - 0.001 19.0 0.8 2.6 7.9 0.2 3.3 2 2 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 CAR29164.1 - 0.0012 18.6 0.1 0.0038 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CAR29164.1 - 0.0012 18.7 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain FeoB_N PF02421.18 CAR29164.1 - 0.0025 17.3 0.0 0.12 11.9 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B Roc PF08477.13 CAR29164.1 - 0.0031 17.7 0.0 0.28 11.4 0.0 2.7 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CAR29164.1 - 0.0049 16.5 0.1 0.11 12.1 0.1 2.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CAR29164.1 - 0.0054 17.0 0.1 0.03 14.6 0.0 2.3 2 1 1 3 3 3 1 AAA domain SRP54 PF00448.22 CAR29164.1 - 0.0073 16.0 0.0 0.069 12.8 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 CAR29164.1 - 0.0086 15.8 0.1 0.067 12.9 0.0 2.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CAR29164.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 CAR29164.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CAR29164.1 - 0.016 15.8 0.2 0.067 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CAR29164.1 - 0.017 14.3 0.1 0.041 13.1 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 CAR29164.1 - 0.038 14.4 0.0 0.079 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 CAR29164.1 - 0.056 12.9 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PRK PF00485.18 CAR29164.1 - 0.061 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 CAR29164.1 - 0.075 13.1 0.1 7 6.7 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain MeaB PF03308.16 CAR29164.1 - 0.091 11.7 0.0 0.94 8.4 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 CAR29164.1 - 0.11 12.9 0.3 1.7 9.1 0.0 2.8 3 0 0 3 3 3 0 RNA helicase G-alpha PF00503.20 CAR29164.1 - 0.18 11.0 3.1 3.1 6.9 0.0 2.9 3 1 0 3 3 3 0 G-protein alpha subunit SRPRB PF09439.10 CAR29164.1 - 0.29 10.5 3.1 0.64 9.4 0.0 2.5 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit EMC3_TMCO1 PF01956.16 CAR29165.1 - 4.6e-54 182.7 0.5 5.4e-54 182.5 0.5 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Izumo-Ig PF16706.5 CAR29166.1 - 0.11 12.6 0.1 0.28 11.2 0.1 1.8 1 1 0 1 1 1 0 Izumo-like Immunoglobulin domain NSP11 PF06471.12 CAR29166.1 - 0.13 10.7 0.1 0.17 10.4 0.1 1.1 1 0 0 1 1 1 0 NSP11 PEMT PF04191.13 CAR29167.1 - 1.1e-33 115.8 3.1 2.2e-33 114.8 3.1 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase Steroid_dh PF02544.16 CAR29167.1 - 0.041 13.9 0.4 0.041 13.9 0.4 1.6 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase YqhR PF11085.8 CAR29167.1 - 1.3 9.0 4.8 6.3 6.7 0.4 2.6 2 1 0 2 2 2 0 Conserved membrane protein YqhR ABC_membrane PF00664.23 CAR29168.1 - 4.2e-96 321.8 31.7 1.3e-49 169.3 11.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAR29168.1 - 1.1e-62 210.6 0.0 4.2e-33 114.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CAR29168.1 - 9.5e-13 48.1 5.6 0.00039 19.9 0.0 4.3 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CAR29168.1 - 6.2e-08 32.7 0.3 0.011 15.6 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase ABC_ATPase PF09818.9 CAR29168.1 - 3.3e-07 29.5 0.1 0.0073 15.2 0.0 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 CAR29168.1 - 3.8e-07 30.5 0.3 0.13 12.6 0.0 3.8 3 1 0 3 3 2 2 AAA domain AAA_29 PF13555.6 CAR29168.1 - 2.7e-06 27.0 0.6 0.035 13.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CAR29168.1 - 7.8e-06 26.4 0.0 0.18 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 CAR29168.1 - 2.2e-05 24.5 0.9 0.027 14.6 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 CAR29168.1 - 0.00012 21.9 3.9 0.17 11.6 0.6 3.1 4 0 0 4 4 3 2 AAA ATPase domain RNA_helicase PF00910.22 CAR29168.1 - 0.00027 21.3 0.1 0.38 11.2 0.0 3.4 3 0 0 3 3 2 1 RNA helicase AAA_7 PF12775.7 CAR29168.1 - 0.0011 18.5 0.1 0.39 10.2 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_18 PF13238.6 CAR29168.1 - 0.002 18.7 0.0 4.9 7.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CAR29168.1 - 0.0027 17.6 1.4 8.6 6.1 0.0 3.5 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 CAR29168.1 - 0.0028 17.6 0.0 0.76 9.8 0.0 3.3 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CAR29168.1 - 0.0029 17.4 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CAR29168.1 - 0.0036 17.4 0.3 0.61 10.1 0.0 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_23 PF13476.6 CAR29168.1 - 0.0048 17.4 1.8 0.42 11.1 0.0 3.1 4 0 0 4 4 2 1 AAA domain DUF815 PF05673.13 CAR29168.1 - 0.0052 16.0 0.1 2.2 7.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 CAR29168.1 - 0.0089 16.0 0.2 0.42 10.5 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AIG1 PF04548.16 CAR29168.1 - 0.017 14.5 0.1 3.6 6.8 0.1 2.7 2 0 0 2 2 2 0 AIG1 family Zeta_toxin PF06414.12 CAR29168.1 - 0.021 14.1 0.0 5.5 6.2 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 CAR29168.1 - 0.028 14.6 0.1 5.7 7.2 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CAR29168.1 - 0.028 13.6 0.1 0.26 10.4 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Ploopntkinase3 PF18751.1 CAR29168.1 - 0.041 13.8 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA PF00004.29 CAR29168.1 - 0.045 14.2 0.2 8.6 6.8 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 CAR29168.1 - 0.045 13.1 0.2 11 5.2 0.0 2.6 2 0 0 2 2 2 0 KaiC DEAD PF00270.29 CAR29168.1 - 0.046 13.5 0.0 0.44 10.3 0.0 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase PRK PF00485.18 CAR29168.1 - 0.066 12.9 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 CAR29168.1 - 0.07 12.3 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit Septin PF00735.18 CAR29168.1 - 0.078 12.2 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Septin Sigma54_activat PF00158.26 CAR29168.1 - 0.094 12.4 0.0 5.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 CAR29168.1 - 0.095 12.9 0.0 20 5.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 CAR29168.1 - 0.11 12.0 0.3 0.56 9.7 0.0 2.3 3 0 0 3 3 2 0 Ferrous iron transport protein B ATP-synt_ab PF00006.25 CAR29168.1 - 0.11 12.1 0.2 0.93 9.1 0.0 2.4 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3987 PF13148.6 CAR29168.1 - 0.12 11.4 0.0 6 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_25 PF13481.6 CAR29168.1 - 0.17 11.5 0.0 18 4.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CAR29168.1 - 0.17 11.6 0.0 13 5.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.20 CAR29168.1 - 0.21 11.5 0.7 30 4.4 0.1 3.6 4 0 0 4 4 3 0 Adenylylsulphate kinase Dynamin_N PF00350.23 CAR29168.1 - 0.45 10.5 3.2 7.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Dynamin family ThiF PF00899.21 CAR29169.1 - 6.8e-109 362.9 0.0 5.3e-73 245.4 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CAR29169.1 - 9.6e-92 307.4 0.3 1.4e-91 306.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CAR29169.1 - 1.6e-33 115.2 0.0 5.5e-33 113.5 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 CAR29169.1 - 3.4e-27 94.4 0.1 7.7e-27 93.3 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CAR29169.1 - 2.5e-24 85.3 1.8 9.9e-24 83.3 1.8 2.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Mog1 PF04603.12 CAR29170.1 - 6.7e-32 110.7 0.0 3.8e-31 108.3 0.0 1.9 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Gly_transf_sug PF04488.15 CAR29171.1 - 1e-13 51.7 0.1 5.6e-13 49.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Gp-FAR-1 PF05823.12 CAR29171.1 - 0.024 15.0 2.0 0.053 13.9 2.0 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) APG6_N PF17675.1 CAR29171.1 - 0.062 13.8 8.0 0.035 14.6 4.6 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region Sec62 PF03839.16 CAR29171.1 - 0.062 12.8 0.5 0.11 12.0 0.5 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 PhaP_Bmeg PF09602.10 CAR29171.1 - 0.064 13.2 4.3 0.14 12.1 4.3 1.5 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) 5_3_exonuc PF01367.20 CAR29171.1 - 0.21 12.2 2.1 0.52 10.9 1.9 1.7 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Noelin-1 PF12308.8 CAR29171.1 - 0.29 11.1 2.8 0.87 9.6 2.8 1.8 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF2967 PF11179.8 CAR29171.1 - 0.42 8.7 2.5 0.59 8.2 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) OmpH PF03938.14 CAR29171.1 - 1.1 9.7 9.9 2 8.8 9.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Septin PF00735.18 CAR29172.1 - 1.3e-103 346.1 0.0 2.2e-103 345.4 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CAR29172.1 - 3.6e-08 33.5 0.0 7.2e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CAR29172.1 - 2.5e-05 24.3 1.0 2.5e-05 24.3 1.0 2.3 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 CAR29172.1 - 4.7e-05 22.8 0.1 0.00011 21.6 0.1 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CAR29172.1 - 6.2e-05 23.1 6.6 0.002 18.2 0.4 2.8 2 1 1 3 3 3 2 Dynamin family IIGP PF05049.13 CAR29172.1 - 0.0008 18.6 0.1 0.0017 17.5 0.1 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 CAR29172.1 - 0.0029 18.1 0.4 0.01 16.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 CAR29172.1 - 0.038 14.2 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CAR29172.1 - 0.091 12.3 0.5 0.39 10.2 0.5 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 CAR29172.1 - 0.098 12.4 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAR29172.1 - 0.12 11.9 0.1 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CAR29172.1 - 0.24 11.2 0.2 0.78 9.5 0.2 1.9 2 1 0 2 2 2 0 P-loop containing region of AAA domain IGPS PF00218.21 CAR29173.1 - 7.8e-94 313.6 0.0 1e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 CAR29173.1 - 2.4e-49 167.7 0.0 4e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CAR29173.1 - 1.3e-09 38.1 0.4 4.3e-09 36.5 0.4 1.8 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 CAR29173.1 - 6.3e-05 22.8 0.1 0.00015 21.6 0.1 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Peripla_BP_2 PF01497.18 CAR29173.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein His_biosynth PF00977.21 CAR29173.1 - 0.018 14.5 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein PDZ PF00595.24 CAR29173.1 - 0.072 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 PDZ domain FMN_dh PF01070.18 CAR29173.1 - 0.095 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Syja_N PF02383.18 CAR29174.1 - 4.5e-84 282.5 0.6 5.8e-84 282.1 0.6 1.1 1 0 0 1 1 1 1 SacI homology domain PUL PF08324.11 CAR29175.1 - 4.7e-44 150.7 1.0 6.4e-44 150.3 1.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 CAR29175.1 - 1.7e-41 141.0 0.3 3.4e-41 140.0 0.3 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CAR29175.1 - 9.3e-29 99.1 22.8 1.3e-07 32.1 0.0 7.4 7 1 1 8 8 8 6 WD domain, G-beta repeat WD40_like PF17005.5 CAR29175.1 - 0.0014 18.0 1.9 0.68 9.2 0.0 2.6 2 1 1 3 3 3 2 WD40-like domain BBS2_Mid PF14783.6 CAR29175.1 - 0.0051 16.8 1.8 2.6 8.1 0.0 3.6 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region Tox-MPTase4 PF15640.6 CAR29175.1 - 0.066 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 4 DUF5053 PF16476.5 CAR29175.1 - 0.14 11.8 0.1 0.46 10.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) FoP_duplication PF13865.6 CAR29176.1 - 1.4e-05 25.6 4.6 2.3e-05 24.9 4.6 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 CAR29176.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ku PF02735.16 CAR29177.1 - 3.1e-34 118.5 0.1 5.4e-34 117.7 0.1 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CAR29177.1 - 4.2e-18 65.9 0.0 1.4e-17 64.2 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain PGM_PMM_I PF02878.16 CAR29178.1 - 3.5e-33 114.2 0.1 5.8e-33 113.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CAR29178.1 - 1.1e-25 90.1 0.0 1.9e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CAR29178.1 - 2.2e-13 50.7 0.0 4.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CAR29178.1 - 1.3e-05 25.3 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.25 CAR29179.1 - 1.7e-67 227.6 0.0 2.4e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29179.1 - 4.4e-31 108.1 0.0 6.2e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CAR29179.1 - 7.4e-12 45.8 0.3 2.4e-11 44.1 0.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CAR29179.1 - 4.6e-06 25.8 0.0 7.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 CAR29179.1 - 0.048 13.3 0.1 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CAR29179.1 - 0.049 12.9 0.0 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CAR29179.1 - 0.13 11.6 0.1 0.27 10.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRN3 PF05327.11 CAR29180.1 - 1.3e-182 608.3 8.3 1.5e-182 608.0 8.3 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 CAR29180.1 - 3.4e-07 28.9 8.1 5.1e-07 28.3 8.1 1.2 1 0 0 1 1 1 1 Nop14-like family Pes-10 PF07149.11 CAR29180.1 - 0.00033 19.8 19.3 0.00041 19.5 18.1 1.6 1 1 1 2 2 2 1 Pes-10 CDC45 PF02724.14 CAR29180.1 - 0.00039 18.9 7.5 0.00056 18.3 7.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Sigma70_ner PF04546.13 CAR29180.1 - 0.095 12.6 19.0 0.21 11.4 19.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF913 PF06025.12 CAR29180.1 - 0.13 11.3 2.2 0.21 10.5 2.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4637 PF15470.6 CAR29180.1 - 1.6 8.5 14.4 3.1 7.5 14.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DNA_pol_phi PF04931.13 CAR29180.1 - 4 5.4 35.9 4.6 5.2 33.2 2.2 2 0 0 2 2 2 0 DNA polymerase phi Vfa1 PF08432.10 CAR29180.1 - 6 7.2 8.6 13 6.1 8.6 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 eIF-3c_N PF05470.12 CAR29180.1 - 9.6 4.4 15.8 10 4.3 14.6 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SPRY PF00622.28 CAR29181.1 - 8.8e-13 48.4 0.8 1.7e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 SPRY domain SRP9-21 PF05486.12 CAR29182.1 - 1.8e-18 66.7 3.8 2.8e-17 62.9 0.0 3.2 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.32 CAR29183.1 - 2.2e-14 53.6 14.1 0.00015 22.5 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29183.1 - 1.1e-08 35.2 0.3 0.07 13.4 0.0 5.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 CAR29184.1 - 8.3e-55 182.7 4.6 6.9e-19 67.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltransf PF01255.19 CAR29185.1 - 7.3e-64 215.4 0.0 9.6e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Vma12 PF11712.8 CAR29186.1 - 3.7e-37 127.5 0.4 3.7e-37 127.5 0.4 1.4 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Pox_A14 PF05767.12 CAR29186.1 - 0.0032 17.6 1.0 0.0051 16.9 1.0 1.3 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 DUF3169 PF11368.8 CAR29186.1 - 0.0094 15.5 0.2 0.013 15.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) TcdB_N PF12918.7 CAR29186.1 - 0.024 14.9 1.5 0.024 14.9 1.5 2.6 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Attachment_P66 PF11263.8 CAR29186.1 - 0.057 12.7 0.1 8.9 5.5 0.0 2.2 2 0 0 2 2 2 0 Borrelia burgdorferi attachment protein P66 zf-MYND PF01753.18 CAR29187.1 - 1.6e-07 31.3 19.4 4.3e-07 29.9 19.4 1.8 1 1 0 1 1 1 1 MYND finger MpPF1 PF07668.11 CAR29187.1 - 0.0028 17.0 3.0 0.0054 16.0 3.0 1.4 1 0 0 1 1 1 1 M penetrans paralogue family 1 Mrx7 PF10906.8 CAR29187.1 - 0.048 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 MIOREX complex component 7 ABM PF03992.16 CAR29188.1 - 3.3e-12 46.3 0.4 4.6e-12 45.9 0.4 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase AntA PF08346.12 CAR29189.1 - 0.087 13.4 0.0 24 5.5 0.0 2.4 2 0 0 2 2 2 0 AntA/AntB antirepressor Aldose_epim PF01263.20 CAR29190.1 - 9e-50 169.7 0.5 1e-49 169.5 0.5 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.25 CAR29191.1 - 1.8e-40 139.0 0.0 3.1e-40 138.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29191.1 - 3.7e-23 82.1 0.0 4.5e-22 78.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase AP_endonuc_2 PF01261.24 CAR29192.1 - 8.6e-33 113.6 0.0 1.1e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel XPG_N PF00752.17 CAR29193.1 - 1.8e-37 127.9 0.0 3.3e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CAR29193.1 - 3.8e-30 104.1 0.4 1.1e-29 102.6 0.1 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 CAR29193.1 - 1.5e-06 28.7 1.1 2e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 CAR29193.1 - 0.012 16.2 0.0 0.046 14.3 0.0 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix domain SOAR PF16533.5 CAR29193.1 - 2.5 8.1 7.7 1.1 9.2 3.0 2.4 2 0 0 2 2 2 0 STIM1 Orai1-activating region Asp PF00026.23 CAR29194.1 - 1.2e-71 241.8 4.0 1.9e-71 241.1 4.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR29194.1 - 8.4e-11 42.4 0.4 2.8e-10 40.7 0.4 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 CAR29194.1 - 5.9e-05 23.6 0.0 5.6 7.6 0.0 3.5 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CAR29194.1 - 0.00033 21.2 0.2 12 6.6 0.0 3.7 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 CAR29194.1 - 0.0022 17.8 0.1 0.12 12.1 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF5094 PF17015.5 CAR29194.1 - 0.12 12.4 3.0 4.4 7.4 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5094) BAF1_ABF1 PF04684.13 CAR29195.1 - 2.9e-168 561.5 26.8 5.9e-80 269.9 1.8 4.3 1 1 2 3 3 3 3 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.15 CAR29195.1 - 0.0011 18.9 0.2 0.0025 17.8 0.2 1.5 1 0 0 1 1 1 1 MuDR family transposase OAD_gamma PF04277.13 CAR29195.1 - 0.58 10.8 0.1 0.58 10.8 0.1 2.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain mRNA_stabil PF13929.6 CAR29196.1 - 8e-110 366.4 0.1 1.2e-109 365.8 0.1 1.2 1 0 0 1 1 1 1 mRNA stabilisation RsfS PF02410.15 CAR29196.1 - 2.4e-20 72.8 0.0 4.6e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation GDYXXLXY PF14345.6 CAR29196.1 - 0.048 13.5 0.2 0.094 12.5 0.1 1.5 2 0 0 2 2 2 0 GDYXXLXY protein KTI12 PF08433.10 CAR29197.1 - 9.4e-96 320.4 0.0 1.1e-95 320.2 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 CAR29197.1 - 0.0013 19.0 0.2 0.0048 17.2 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 CAR29197.1 - 0.0023 18.5 0.0 0.0096 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR29197.1 - 0.0072 16.5 0.0 0.019 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CAR29197.1 - 0.048 14.1 0.1 0.36 11.2 0.0 2.2 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) RasGEF_N PF00618.20 CAR29197.1 - 0.1 12.8 0.1 3 8.1 0.0 2.4 2 0 0 2 2 2 0 RasGEF N-terminal motif AAA_16 PF13191.6 CAR29197.1 - 0.11 12.9 0.0 0.33 11.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.20 CAR29197.1 - 0.11 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 CAR29198.1 - 1.9e-15 57.0 0.0 3.8e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR29198.1 - 1.6e-06 27.7 0.1 3.2e-06 26.8 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAR29198.1 - 5e-06 26.5 1.3 1.1e-05 25.4 1.3 1.7 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 CAR29198.1 - 0.00063 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 CAR29198.1 - 0.011 14.8 0.2 0.018 14.1 0.2 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Septin PF00735.18 CAR29198.1 - 0.047 13.0 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.23 CAR29198.1 - 0.066 13.3 1.0 1.7 8.7 0.2 2.5 1 1 1 2 2 2 0 Dynamin family SRPRB PF09439.10 CAR29198.1 - 0.067 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 CAR29198.1 - 0.068 13.7 1.8 0.32 11.5 0.2 2.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CAR29198.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 CAR29198.1 - 0.13 11.3 1.5 0.57 9.1 0.3 2.0 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 CAR29198.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_24 PF13479.6 CAR29198.1 - 0.25 11.0 0.2 0.66 9.7 0.1 1.6 2 0 0 2 2 2 0 AAA domain Metallothi_Euk2 PF12809.7 CAR29199.1 - 0.19 12.0 37.1 0.24 11.7 37.1 1.2 1 0 0 1 1 1 0 Eukaryotic metallothionein Hap4_Hap_bind PF10297.9 CAR29200.1 - 1.1e-08 34.9 8.6 2.5e-08 33.8 8.6 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 DUF3134 PF11332.8 CAR29200.1 - 0.069 13.5 2.5 0.074 13.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) bZIP_1 PF00170.21 CAR29200.1 - 0.22 11.6 2.6 0.42 10.7 2.6 1.5 1 0 0 1 1 1 0 bZIP transcription factor ZapB PF06005.12 CAR29200.1 - 0.34 11.4 2.4 0.77 10.2 2.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DUF4813 PF16072.5 CAR29200.1 - 1.7 8.2 26.4 0.1 12.3 20.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) PRKG1_interact PF15898.5 CAR29200.1 - 7.1 7.6 10.1 0.55 11.2 0.2 3.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain SOR_SNZ PF01680.17 CAR29201.1 - 2.1e-106 354.3 6.2 2.7e-106 353.9 6.2 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 CAR29201.1 - 1.8e-08 34.0 1.0 1.4e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 CAR29201.1 - 0.00072 18.7 1.1 2 7.4 0.0 3.0 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 CAR29201.1 - 0.0028 17.7 0.0 0.036 14.1 0.0 2.3 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Fapy_DNA_glyco PF01149.24 CAR29201.1 - 0.0053 17.4 0.0 2.1 9.0 0.0 3.1 2 2 1 3 3 3 1 Formamidopyrimidine-DNA glycosylase N-terminal domain NanE PF04131.14 CAR29201.1 - 0.013 14.7 1.4 0.14 11.4 0.0 2.7 2 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase TMP-TENI PF02581.17 CAR29201.1 - 0.013 14.9 0.3 0.27 10.6 0.1 2.4 2 0 0 2 2 2 0 Thiamine monophosphate synthase NMO PF03060.15 CAR29201.1 - 0.02 14.3 1.8 0.047 13.1 0.1 2.2 3 0 0 3 3 3 0 Nitronate monooxygenase His_biosynth PF00977.21 CAR29201.1 - 0.026 14.0 0.1 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein IGPS PF00218.21 CAR29201.1 - 0.051 12.7 0.1 1.3 8.1 0.0 2.5 2 2 0 2 2 2 0 Indole-3-glycerol phosphate synthase DUF4391 PF14335.6 CAR29201.1 - 0.071 12.8 0.4 0.12 12.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) Nitr_red_bet_C PF14711.6 CAR29201.1 - 0.085 12.6 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal Peptidase_S66C PF17676.1 CAR29201.1 - 0.092 13.3 0.0 0.34 11.4 0.0 1.9 2 0 0 2 2 2 0 LD-carboxypeptidase C-terminal domain 1-cysPrx_C PF10417.9 CAR29201.1 - 0.13 12.1 0.7 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin Asr PF06392.11 CAR29201.1 - 2 8.9 3.9 4.8 7.7 3.9 1.6 1 0 0 1 1 1 0 Acid shock protein repeat SNO PF01174.19 CAR29202.1 - 1.3e-86 289.3 0.0 1.5e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 CAR29202.1 - 1.3e-08 34.7 0.0 3.9e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 CAR29202.1 - 0.00067 19.4 0.0 0.0066 16.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase family S51 GATase PF00117.28 CAR29202.1 - 0.0016 18.2 0.0 0.0032 17.3 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I BPL_N PF09825.9 CAR29202.1 - 0.02 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DJ-1_PfpI PF01965.24 CAR29202.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Drc1-Sld2 PF11719.8 CAR29204.1 - 4e-41 142.0 38.9 1.2e-38 133.9 38.9 2.1 1 1 0 1 1 1 1 DNA replication and checkpoint protein UTP15_C PF09384.10 CAR29205.1 - 6.4e-43 146.0 0.4 1.2e-42 145.0 0.4 1.5 1 1 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CAR29205.1 - 3e-15 56.3 10.0 0.0026 18.6 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29205.1 - 7.9e-06 26.1 0.0 0.039 14.2 0.0 4.5 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CAR29206.1 - 1.2e-15 57.5 16.8 0.021 15.7 0.0 10.2 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29206.1 - 4.1e-10 39.8 0.3 2.4e-05 24.5 0.0 6.0 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR29206.1 - 4.6e-08 33.2 0.0 7.7e-05 22.7 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 CAR29206.1 - 0.00065 19.3 0.5 0.14 11.7 0.4 2.9 2 1 1 3 3 3 2 PQQ-like domain RAB3GAP2_N PF14655.6 CAR29206.1 - 0.0089 15.3 0.0 0.058 12.6 0.0 2.2 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_like PF17005.5 CAR29206.1 - 0.038 13.3 0.1 1.4 8.1 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain CRC_subunit PF08624.10 CAR29207.1 - 1.2e-52 178.0 0.1 2.1e-52 177.1 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Peptidase_M41 PF01434.18 CAR29208.1 - 1.8e-66 223.6 2.6 1.7e-65 220.4 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CAR29208.1 - 2.2e-39 134.9 0.0 5.9e-39 133.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR29208.1 - 8.3e-14 51.1 0.0 1.2e-12 47.4 0.1 2.7 2 0 0 2 2 2 1 AAA+ lid domain FtsH_ext PF06480.15 CAR29208.1 - 4.6e-07 30.2 0.5 1.5e-06 28.5 0.5 2.0 1 1 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.6 CAR29208.1 - 0.0013 19.1 1.6 0.011 16.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CAR29208.1 - 0.0054 17.1 0.1 0.029 14.7 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 CAR29208.1 - 0.0087 15.3 0.0 0.022 14.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CAR29208.1 - 0.03 14.1 0.0 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain CAMSAP_CC1 PF17095.5 CAR29208.1 - 0.044 13.6 2.9 0.13 12.1 2.9 1.7 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin AAA_33 PF13671.6 CAR29208.1 - 0.053 13.7 0.8 0.73 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CAR29208.1 - 0.073 13.3 0.1 2.7 8.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CAR29208.1 - 0.13 12.2 3.5 0.35 10.9 0.1 3.0 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF883 PF05957.13 CAR29208.1 - 0.17 12.5 4.4 0.63 10.7 4.4 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Presenilin PF01080.17 CAR29208.1 - 8.5 5.0 6.6 18 4.0 6.6 1.5 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 CAR29209.1 - 3.2e-35 121.7 34.9 3.2e-35 121.7 34.9 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR29209.1 - 2.1e-14 53.3 7.4 2.1e-14 53.3 7.4 4.0 2 1 1 3 3 3 1 Sugar (and other) transporter Fzo_mitofusin PF04799.13 CAR29209.1 - 0.35 10.4 3.0 3.1 7.3 0.6 2.6 2 0 0 2 2 2 0 fzo-like conserved region DUF2157 PF09925.9 CAR29209.1 - 0.59 9.9 7.5 0.31 10.8 3.3 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) Macro_2 PF14519.6 CAR29210.1 - 7.6e-98 327.3 0.0 8.8e-98 327.1 0.0 1.0 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.21 CAR29210.1 - 0.00098 19.2 0.0 0.0044 17.1 0.0 2.1 2 1 0 2 2 2 1 Macro domain Aminotran_1_2 PF00155.21 CAR29211.1 - 2.3e-86 290.2 0.0 2.7e-86 290.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SIS PF01380.22 CAR29213.1 - 1.9e-64 215.4 0.0 2.1e-32 111.7 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CAR29213.1 - 2.2e-16 60.3 0.0 4.3e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CAR29213.1 - 1e-09 38.4 0.0 2.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CAR29213.1 - 2.7e-05 23.2 0.1 4.6e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Peptidase_M18 PF02127.15 CAR29214.1 - 2.6e-143 477.9 0.0 3e-143 477.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Pkinase PF00069.25 CAR29215.1 - 1.5e-69 234.3 0.0 2.3e-63 214.0 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29215.1 - 2.8e-34 118.6 0.0 1.2e-32 113.3 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.20 CAR29215.1 - 0.0049 16.5 1.8 0.018 14.7 0.1 2.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 CAR29215.1 - 0.0071 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR29215.1 - 0.027 14.4 0.0 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family ADH_N PF08240.12 CAR29216.1 - 8.8e-29 99.6 1.3 1.5e-28 98.8 1.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR29216.1 - 5.8e-26 91.0 0.3 9.4e-26 90.3 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR29216.1 - 1.1e-05 26.5 0.0 1.9e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CAR29216.1 - 0.03 13.8 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ADH_N PF08240.12 CAR29217.1 - 1.1e-27 96.0 1.4 1.9e-27 95.3 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR29217.1 - 5.5e-22 78.1 0.1 9.7e-22 77.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CAR29217.1 - 1.1e-11 45.9 0.0 1.7e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 CAR29217.1 - 0.062 12.8 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 CAR29217.1 - 0.17 11.3 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Metallophos PF00149.28 CAR29218.1 - 1.8e-38 133.1 0.1 2.8e-38 132.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAR29218.1 - 1.5e-15 57.3 0.3 2.8e-15 56.5 0.3 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Sulfatase PF00884.23 CAR29219.1 - 1.5e-63 215.1 0.0 2.1e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CAR29219.1 - 0.0003 20.5 0.6 0.0024 17.5 0.2 2.2 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CAR29219.1 - 0.0017 17.0 0.0 0.002 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) PHD PF00628.29 CAR29220.1 - 1.7e-10 40.7 7.6 3e-10 39.8 7.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_Oberon PF07227.11 CAR29220.1 - 0.24 11.3 1.2 0.5 10.3 1.2 1.5 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein PHD_3 PF13922.6 CAR29220.1 - 0.53 10.7 4.9 0.26 11.7 0.5 2.8 2 1 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Sec1 PF00995.23 CAR29221.1 - 6.2e-123 412.0 8.8 7e-123 411.9 8.8 1.0 1 0 0 1 1 1 1 Sec1 family LAGLIDADG_1 PF00961.19 CAR29221.1 - 0.086 13.8 2.3 5.8 7.9 0.1 2.8 2 0 0 2 2 2 0 LAGLIDADG endonuclease YxiJ PF14176.6 CAR29221.1 - 0.13 12.8 2.1 2.1 8.9 0.1 3.0 3 0 0 3 3 3 0 YxiJ-like protein TCO89 PF10452.9 CAR29222.1 - 3.4e-127 425.9 58.4 8.8e-126 421.3 58.4 2.1 1 1 0 1 1 1 1 TORC1 subunit TCO89 UCH_1 PF13423.6 CAR29223.1 - 7.3e-64 216.4 2.1 1.3e-63 215.6 2.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 CAR29223.1 - 2.8e-19 70.3 0.0 5.1e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Exonuclease WD40 PF00400.32 CAR29223.1 - 0.0018 19.0 0.1 0.16 12.9 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29223.1 - 0.019 15.3 0.0 2 8.7 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_C28 PF05408.11 CAR29223.1 - 0.074 12.8 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase WD40 PF00400.32 CAR29224.1 - 7e-20 71.0 12.6 2.4e-05 25.0 0.1 9.0 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29224.1 - 2.9e-09 37.1 8.3 0.032 14.5 0.8 7.1 7 2 1 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR29224.1 - 2e-05 23.4 5.9 0.0064 15.2 0.4 4.0 3 1 1 4 4 4 3 Nucleoporin Nup120/160 CPSF_A PF03178.15 CAR29224.1 - 0.0017 17.7 1.3 12 5.1 0.0 4.8 5 1 0 5 5 5 2 CPSF A subunit region WD40_like PF17005.5 CAR29224.1 - 0.0046 16.3 1.0 0.0046 16.3 1.0 4.4 2 1 1 3 3 3 1 WD40-like domain Hira PF07569.11 CAR29224.1 - 0.19 11.4 3.5 7.3 6.2 0.2 4.1 4 0 0 4 4 4 0 TUP1-like enhancer of split Type_III_YscX PF09474.10 CAR29225.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) KH_1 PF00013.29 CAR29226.1 - 7.7e-11 41.7 0.0 0.0034 17.2 0.0 3.7 3 0 0 3 3 3 3 KH domain Hydrolase_4 PF12146.8 CAR29227.1 - 1.5e-46 158.6 0.0 1.8e-46 158.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CAR29227.1 - 3.1e-17 63.1 0.0 5.1e-15 55.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR29227.1 - 3.1e-09 37.8 0.0 4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CAR29227.1 - 0.0028 17.2 0.0 0.32 10.5 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 CAR29227.1 - 0.0036 16.0 0.4 0.79 8.3 0.0 2.8 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) LCAT PF02450.15 CAR29227.1 - 0.031 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Thioesterase PF00975.20 CAR29227.1 - 0.033 14.3 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 CAR29227.1 - 0.038 13.6 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 CAR29227.1 - 0.15 11.5 0.2 0.75 9.2 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family PGAP1 PF07819.13 CAR29227.1 - 0.2 11.3 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein MBR1 PF17058.5 CAR29228.1 - 2.4e-13 50.9 0.4 2e-08 34.8 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial biogenesis regulation protein 1 NUP50 PF08911.11 CAR29228.1 - 0.065 13.9 0.0 0.2 12.3 0.0 1.9 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) UPF1_Zn_bind PF09416.10 CAR29229.1 - 2.7e-64 215.8 8.9 3.3e-64 215.5 6.3 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CAR29229.1 - 7.6e-59 198.7 0.0 1.3e-58 198.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CAR29229.1 - 3.5e-46 158.1 8.1 1.6e-24 87.1 0.8 2.7 2 1 1 3 3 3 2 AAA domain DUF5599 PF18141.1 CAR29229.1 - 2.7e-28 98.0 0.0 1e-27 96.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CAR29229.1 - 7.1e-17 61.8 0.1 3.3e-16 59.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR29229.1 - 4.9e-13 49.6 0.1 1.1e-12 48.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CAR29229.1 - 0.00018 20.8 0.1 0.0046 16.2 0.0 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 CAR29229.1 - 0.00025 21.1 0.0 0.00055 20.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CAR29229.1 - 0.00087 19.1 0.0 0.77 9.5 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CAR29229.1 - 0.0024 17.8 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 Helicase AAA_24 PF13479.6 CAR29229.1 - 0.015 15.0 0.2 0.036 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CAR29229.1 - 0.026 14.0 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_10 PF12846.7 CAR29229.1 - 0.035 13.0 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain PIF1 PF05970.14 CAR29229.1 - 0.073 12.2 0.0 7.2 5.7 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 CAR29229.1 - 0.087 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 CAR29229.1 - 0.097 12.4 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase T2SSE PF00437.20 CAR29229.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RasGAP PF00616.19 CAR29230.1 - 1.8e-39 135.7 0.5 6e-38 130.6 0.5 2.8 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 CAR29230.1 - 2.3e-05 24.6 0.0 5.5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain CRAL_TRIO PF00650.20 CAR29231.1 - 8.5e-37 126.3 0.1 1.2e-36 125.8 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CAR29231.1 - 6.3e-10 39.1 0.2 1.4e-09 38.0 0.2 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CAR29231.1 - 0.001 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 CAR29231.1 - 0.12 12.5 0.1 0.26 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) AAA PF00004.29 CAR29232.1 - 1.2e-12 48.4 0.0 2.7e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CAR29232.1 - 6.7e-07 29.4 0.1 1.6e-05 24.9 0.1 2.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CAR29232.1 - 3e-05 24.5 0.0 7.6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CAR29232.1 - 0.00022 21.0 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CAR29232.1 - 0.00033 20.7 0.0 0.067 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CAR29232.1 - 0.00091 19.5 0.0 0.0046 17.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 CAR29232.1 - 0.0033 17.7 0.0 0.025 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA C-terminal domain RsgA_GTPase PF03193.16 CAR29232.1 - 0.004 17.1 0.0 0.0083 16.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 CAR29232.1 - 0.0054 17.1 0.0 0.02 15.3 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 CAR29232.1 - 0.0072 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CAR29232.1 - 0.019 14.9 0.0 0.067 13.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CAR29232.1 - 0.031 13.4 0.0 0.067 12.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 CAR29232.1 - 0.052 13.3 0.2 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CAR29232.1 - 0.11 13.1 0.5 0.68 10.5 0.0 2.6 3 1 0 3 3 2 0 AAA domain ABC_tran PF00005.27 CAR29232.1 - 0.44 11.0 1.8 1.1 9.7 0.0 2.6 3 1 0 3 3 3 0 ABC transporter Snf7 PF03357.21 CAR29233.1 - 4e-29 101.4 6.6 5.1e-29 101.1 6.6 1.1 1 0 0 1 1 1 1 Snf7 DnaJ-X PF14308.6 CAR29234.1 - 1.9e-74 249.7 4.1 1.9e-74 249.7 4.1 2.4 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CAR29234.1 - 1.2e-23 83.0 1.5 1.2e-23 83.0 1.5 2.2 2 0 0 2 2 2 1 DnaJ domain Anoctamin PF04547.12 CAR29234.1 - 0.5 9.1 2.7 0.72 8.6 2.7 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel Neur_chan_memb PF02932.16 CAR29234.1 - 1.6 8.7 8.1 2 8.4 6.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Atg14 PF10186.9 CAR29234.1 - 5.6 6.0 15.5 11 5.0 15.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CAR29234.1 - 5.6 6.2 12.7 2.1 7.7 9.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Aim21 PF11489.8 CAR29235.1 - 8.3e-06 25.0 97.6 8.3e-06 25.0 97.6 7.2 2 2 4 6 6 6 2 Altered inheritance of mitochondria protein 21 NTF2 PF02136.20 CAR29236.1 - 3.4e-36 124.4 0.3 3.8e-36 124.3 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 CAR29236.1 - 0.0017 17.6 0.3 0.006 15.8 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) Glyco_transf_52 PF07922.11 CAR29236.1 - 0.015 14.6 0.4 0.18 11.1 0.0 2.0 1 1 1 2 2 2 0 Glycosyltransferase family 52 DUF4440 PF14534.6 CAR29236.1 - 0.067 13.6 0.0 0.083 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Sec3_C PF09763.9 CAR29237.1 - 2.7e-152 508.7 11.5 2.7e-152 508.7 11.5 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 CAR29237.1 - 6.6e-25 87.1 0.5 1.6e-24 85.9 0.5 1.7 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 CAR29237.1 - 1.6e-07 30.5 3.3 1.6e-07 30.5 3.3 2.2 2 0 0 2 2 2 1 Vps52 / Sac2 family ResIII PF04851.15 CAR29238.1 - 2.4e-20 73.3 0.0 2.4e-20 73.3 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAR29238.1 - 4.2e-20 72.1 0.5 3.6e-19 69.2 0.2 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAR29238.1 - 9.3e-18 64.6 0.3 3.4e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 CAR29238.1 - 7.8e-06 24.8 0.0 1.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 CAR29238.1 - 0.1 12.9 0.0 2.2 8.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain DUF2203 PF09969.9 CAR29238.1 - 2.2 9.0 6.1 3.6 8.3 2.9 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) EF-hand_4 PF12763.7 CAR29239.1 - 9.8e-27 93.0 0.1 1.9e-13 50.3 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 CAR29239.1 - 5.4e-15 55.6 173.7 3.4e-06 27.4 28.3 14.5 6 2 9 15 15 15 8 Domain of unknown function (DUF1720) EF-hand_7 PF13499.6 CAR29239.1 - 6.9e-08 32.8 0.0 0.00098 19.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CAR29239.1 - 1.2e-06 27.6 0.0 0.022 14.3 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CAR29239.1 - 1.4e-05 24.6 0.2 1.3 9.2 0.1 3.7 4 0 0 4 4 4 2 EF-hand domain RRM_1 PF00076.22 CAR29240.1 - 2.6e-18 65.6 0.0 5e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR29240.1 - 0.00048 20.2 0.0 0.001 19.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RraA-like PF03737.15 CAR29241.1 - 2e-31 109.2 0.0 3.1e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Aldolase/RraA Mannosyl_trans3 PF11051.8 CAR29242.1 - 9.4e-73 244.9 0.0 1.5e-72 244.2 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative bZIP_2 PF07716.15 CAR29243.1 - 1.2e-07 31.7 10.7 1.2e-07 31.7 10.7 2.5 1 1 2 3 3 3 1 Basic region leucine zipper YadA_stalk PF05662.14 CAR29243.1 - 0.014 15.7 0.1 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin bZIP_1 PF00170.21 CAR29243.1 - 0.14 12.2 16.1 0.67 10.1 15.6 2.3 1 1 0 1 1 1 0 bZIP transcription factor NRBF2 PF08961.10 CAR29243.1 - 0.24 11.0 9.3 0.41 10.2 9.3 1.4 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Presenilin PF01080.17 CAR29243.1 - 2.5 6.8 4.6 2.4 6.8 4.6 1.1 1 0 0 1 1 1 0 Presenilin RPA43_OB PF17875.1 CAR29244.1 - 0.048 14.3 3.2 0.15 12.7 3.2 1.8 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I EIIBC-GUT_N PF03612.14 CAR29244.1 - 0.97 9.1 5.9 2.7 7.7 5.9 1.7 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CobT PF06213.12 CAR29244.1 - 4.6 6.5 11.6 9.2 5.6 11.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Proteasome PF00227.26 CAR29245.1 - 6e-57 192.2 0.0 8e-57 191.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR29245.1 - 2.7e-12 46.1 0.2 6e-12 45.0 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature TOM13 PF08219.11 CAR29246.1 - 5.6e-20 71.1 0.0 6.4e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 Rpr2 PF04032.16 CAR29247.1 - 9.6e-16 57.9 0.7 1.4e-15 57.3 0.7 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain LETM1 PF07766.13 CAR29249.1 - 2.9e-100 335.0 2.6 2.9e-100 335.0 2.6 1.6 2 0 0 2 2 2 1 LETM1-like protein bZIP_1 PF00170.21 CAR29250.1 - 4e-05 23.6 14.0 0.00012 22.1 13.9 1.8 1 1 0 1 1 1 1 bZIP transcription factor Hap4_Hap_bind PF10297.9 CAR29250.1 - 9.3e-05 22.4 6.9 0.00026 21.0 6.9 1.8 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 MAD PF05557.13 CAR29250.1 - 0.01 14.3 7.8 0.018 13.5 7.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein CDT1_C PF16679.5 CAR29250.1 - 0.013 15.9 0.5 0.034 14.6 0.5 1.7 1 0 0 1 1 1 0 DNA replication factor Cdt1 C-terminal domain KxDL PF10241.9 CAR29250.1 - 0.073 13.3 1.9 0.21 11.9 1.9 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF2730 PF10805.8 CAR29250.1 - 0.088 12.9 1.8 0.18 11.9 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Herpes_UL6 PF01763.16 CAR29250.1 - 0.092 11.2 1.4 0.22 10.0 1.4 1.5 1 1 1 2 2 2 0 Herpesvirus UL6 like bZIP_2 PF07716.15 CAR29250.1 - 0.096 12.8 15.6 0.75 9.9 12.4 2.4 1 1 1 2 2 2 0 Basic region leucine zipper FAA_hydro_N_2 PF18288.1 CAR29250.1 - 0.13 12.7 0.5 0.37 11.2 0.5 1.8 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal domain 2 Spc24 PF08286.11 CAR29250.1 - 0.13 12.5 2.0 0.47 10.7 2.0 2.0 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 CAR29250.1 - 0.14 12.6 0.7 3 8.3 0.7 2.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1943 PF09172.11 CAR29250.1 - 0.32 10.2 1.4 0.57 9.4 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Cluap1 PF10234.9 CAR29250.1 - 0.49 9.7 6.0 0.42 10.0 4.3 1.6 2 0 0 2 2 2 0 Clusterin-associated protein-1 bZIP_Maf PF03131.17 CAR29250.1 - 2.8 8.5 12.8 0.55 10.8 8.7 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Cortex-I_coil PF09304.10 CAR29250.1 - 3.3 8.0 10.8 6.1 7.1 7.0 2.7 3 0 0 3 3 3 0 Cortexillin I, coiled coil Glyco_hydro_72 PF03198.14 CAR29251.1 - 6.9e-144 478.9 9.0 9.2e-144 478.5 9.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase SUR7 PF06687.12 CAR29252.1 - 6.9e-13 48.7 17.2 1e-12 48.2 17.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family CitMHS PF03600.16 CAR29252.1 - 0.0055 15.9 0.0 0.011 15.0 0.0 1.5 2 0 0 2 2 2 1 Citrate transporter DUF2207 PF09972.9 CAR29252.1 - 1.5 7.4 3.3 2.8 6.6 3.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SNARE PF05739.19 CAR29253.1 - 1.5e-15 56.9 0.2 1.5e-15 56.9 0.2 2.2 3 0 0 3 3 3 1 SNARE domain Scaffolding_pro PF11418.8 CAR29253.1 - 0.00073 20.0 0.0 0.0024 18.4 0.0 1.9 1 0 0 1 1 1 1 Phi29 scaffolding protein MYO10_CC PF16735.5 CAR29253.1 - 0.63 10.2 11.3 0.089 12.9 3.4 3.0 2 1 0 2 2 2 0 Unconventional myosin-X coiled coil domain SPA PF08616.10 CAR29254.1 - 5e-25 87.7 0.0 1e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 CAR29254.1 - 2.7e-23 82.9 0.1 1.2e-22 80.8 0.1 2.0 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking TPP_enzyme_N PF02776.18 CAR29255.1 - 1.9e-27 96.0 0.0 3.4e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR29255.1 - 3e-20 72.4 0.0 5.1e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CAR29255.1 - 2.6e-15 56.5 0.0 6e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain AIRC PF00731.20 CAR29256.1 - 4.5e-64 214.5 1.4 8.2e-64 213.7 1.4 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 CAR29256.1 - 1.3e-60 203.9 0.0 2.2e-60 203.1 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 CAR29256.1 - 9.8e-19 66.8 0.0 1.8e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain 2-Hacid_dh_C PF02826.19 CAR29256.1 - 6e-05 22.5 0.0 0.00013 21.4 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CAR29256.1 - 6.7e-05 22.3 0.1 0.00018 20.9 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain CPSase_L_D2 PF02786.17 CAR29256.1 - 0.0093 15.5 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 CAR29256.1 - 0.028 13.9 0.0 0.14 11.7 0.0 2.1 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus CoA_binding_2 PF13380.6 CAR29256.1 - 0.13 12.8 0.5 10 6.7 0.0 2.9 2 1 1 3 3 3 0 CoA binding domain NPV_P10 PF05531.12 CAR29256.1 - 0.13 12.7 0.1 0.31 11.5 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Complex1_LYR PF05347.15 CAR29257.1 - 1.2e-14 54.1 0.1 1.4e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CAR29257.1 - 0.0015 19.2 0.2 0.0018 19.0 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RhoGAP PF00620.27 CAR29258.1 - 4.3e-46 156.5 0.9 8.4e-46 155.5 0.1 1.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 CAR29258.1 - 5.3e-11 42.6 30.0 2.5e-06 27.6 7.6 2.6 2 0 0 2 2 2 2 LIM domain HLH PF00010.26 CAR29259.1 - 3.2e-13 49.4 3.4 7.5e-13 48.2 3.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4363 PF14276.6 CAR29259.1 - 0.0041 17.2 3.1 0.0048 17.0 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4363) DUF1221 PF06760.11 CAR29259.1 - 0.063 12.8 1.8 0.08 12.4 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1221) Pkinase PF00069.25 CAR29260.1 - 2.2e-35 122.3 0.0 3.2e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29260.1 - 5.1e-15 55.5 0.0 7.7e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR29260.1 - 0.0029 17.0 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CAR29260.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA PF00004.29 CAR29261.1 - 7.9e-52 175.2 0.0 1.1e-43 148.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CAR29261.1 - 8.2e-23 80.6 0.3 3.1e-22 78.8 0.3 2.1 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 CAR29261.1 - 2.9e-11 44.0 0.3 0.00034 21.0 0.0 3.6 2 1 1 3 3 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 CAR29261.1 - 1.2e-10 41.1 0.0 6.4e-06 25.9 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain NACHT PF05729.12 CAR29261.1 - 3e-08 33.7 0.7 0.00012 22.0 0.0 3.3 3 0 0 3 3 3 2 NACHT domain AAA_14 PF13173.6 CAR29261.1 - 4.3e-08 33.3 0.0 0.00085 19.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CAR29261.1 - 1.6e-07 31.6 0.0 0.0056 16.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 CAR29261.1 - 9.9e-07 29.1 1.1 0.012 15.9 0.0 3.8 3 2 0 3 3 3 2 AAA domain AAA_5 PF07728.14 CAR29261.1 - 1e-06 28.8 0.2 0.084 12.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CAR29261.1 - 2.4e-06 27.4 0.0 0.015 15.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 CAR29261.1 - 3.9e-06 26.9 0.1 0.056 13.4 0.1 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CAR29261.1 - 6.3e-06 26.0 0.0 0.0038 17.0 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CAR29261.1 - 1.1e-05 25.7 0.0 0.027 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 CAR29261.1 - 1.5e-05 25.5 0.0 0.02 15.4 0.0 3.0 2 1 0 2 2 2 1 ABC transporter Rad17 PF03215.15 CAR29261.1 - 1.8e-05 24.7 0.1 0.024 14.5 0.1 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 CAR29261.1 - 2.2e-05 25.0 0.3 0.36 11.4 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CAR29261.1 - 5.4e-05 23.5 0.0 0.36 11.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CAR29261.1 - 0.0001 22.7 0.0 0.93 9.9 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_17 PF13207.6 CAR29261.1 - 0.00013 22.4 0.8 0.72 10.3 0.2 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 CAR29261.1 - 0.00043 19.5 0.0 0.29 10.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 CAR29261.1 - 0.00057 19.7 0.0 0.24 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CAR29261.1 - 0.00057 19.5 0.7 0.82 9.2 0.0 3.4 3 1 1 4 4 4 1 AAA domain SKI PF01202.22 CAR29261.1 - 0.00071 19.7 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Shikimate kinase ATPase_2 PF01637.18 CAR29261.1 - 0.0011 19.0 0.2 0.18 11.7 0.0 3.0 2 2 1 3 3 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CAR29261.1 - 0.0014 18.2 0.2 0.5 9.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 CAR29261.1 - 0.0019 18.1 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 CAR29261.1 - 0.0023 17.8 0.0 0.23 11.3 0.0 2.7 2 0 0 2 2 2 1 Bacterial dnaA protein ATPase PF06745.13 CAR29261.1 - 0.0029 17.0 0.0 2.6 7.3 0.0 2.5 2 0 0 2 2 2 2 KaiC CbiA PF01656.23 CAR29261.1 - 0.0032 17.5 0.0 0.009 16.1 0.0 1.8 2 0 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Viral_helicase1 PF01443.18 CAR29261.1 - 0.0034 17.2 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 CAR29261.1 - 0.0034 16.7 0.0 2.7 7.2 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Vps4_C PF09336.10 CAR29261.1 - 0.0051 16.8 0.1 0.017 15.1 0.1 1.8 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_19 PF13245.6 CAR29261.1 - 0.0069 16.7 0.0 0.23 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CAR29261.1 - 0.012 14.9 0.0 0.16 11.2 0.0 2.4 2 0 0 2 2 2 0 TIP49 P-loop domain DUF2075 PF09848.9 CAR29261.1 - 0.015 14.6 0.0 5.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CAR29261.1 - 0.017 14.9 0.0 0.5 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CAR29261.1 - 0.017 14.4 0.2 0.078 12.2 0.0 2.2 3 0 0 3 3 3 0 KAP family P-loop domain T2SSE PF00437.20 CAR29261.1 - 0.017 14.2 0.1 0.084 11.9 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 CAR29261.1 - 0.02 14.6 0.0 7 6.3 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain PduV-EutP PF10662.9 CAR29261.1 - 0.022 14.5 0.3 1 9.1 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 CAR29261.1 - 0.027 14.3 0.1 0.16 11.7 0.1 2.3 3 0 0 3 3 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 CAR29261.1 - 0.037 13.9 0.5 0.11 12.4 0.1 2.0 2 0 0 2 2 1 0 RsgA GTPase Mg_chelatase PF01078.21 CAR29261.1 - 0.049 13.0 0.2 0.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 CAR29261.1 - 0.062 13.1 0.0 1.7 8.4 0.1 2.6 3 0 0 3 3 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CAR29261.1 - 0.1 12.5 0.1 5.9 6.8 0.0 2.5 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 CAR29261.1 - 0.1 12.2 0.5 0.44 10.2 0.1 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Clat_adaptor_s PF01217.20 CAR29262.1 - 8.9e-54 181.3 2.3 1e-53 181.1 2.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Thymidylate_kin PF02223.17 CAR29263.1 - 1.2e-39 135.9 0.0 1.4e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.6 CAR29263.1 - 0.0036 17.5 0.1 0.015 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain RnlB_antitoxin PF15933.5 CAR29263.1 - 0.064 13.6 0.2 38 4.7 0.1 3.4 3 1 1 4 4 4 0 Antitoxin to bacterial toxin RNase LS or RnlA EDR1 PF14381.6 CAR29263.1 - 0.086 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 AAA_18 PF13238.6 CAR29263.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4588 PF15251.6 CAR29265.1 - 1.2e-06 28.5 4.4 1.2e-05 25.3 4.4 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) PBP_sp32 PF07222.12 CAR29265.1 - 0.012 15.1 1.2 0.018 14.5 1.2 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SUR7 PF06687.12 CAR29266.1 - 1.2e-33 116.6 7.8 1.5e-33 116.2 7.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family GFO_IDH_MocA PF01408.22 CAR29267.1 - 1.8e-07 32.0 0.0 2.9e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CAR29267.1 - 0.022 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Hit1_C PF18268.1 CAR29268.1 - 1.7e-41 140.2 0.8 2.8e-41 139.5 0.8 1.4 1 0 0 1 1 1 1 Hit1 C-terminal zf-HIT PF04438.16 CAR29268.1 - 4.8e-12 45.5 10.7 7.9e-12 44.8 10.7 1.4 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 CAR29268.1 - 0.0055 16.4 0.3 0.017 14.8 0.1 1.9 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain zf-Mss51 PF13824.6 CAR29268.1 - 0.1 12.7 6.4 0.21 11.7 6.4 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 CAR29268.1 - 0.1 12.7 10.1 0.19 11.9 10.1 1.4 1 0 0 1 1 1 0 MYND finger DUF2089 PF09862.9 CAR29268.1 - 0.13 12.3 0.0 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) zf-C6H2 PF15801.5 CAR29268.1 - 0.29 11.5 7.0 0.6 10.5 7.0 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-B_box PF00643.24 CAR29268.1 - 2.5 8.3 9.7 1.1 9.5 6.4 1.9 2 0 0 2 2 2 0 B-box zinc finger Suc_Fer-like PF06999.12 CAR29269.1 - 3.9e-34 118.2 0.0 4.9e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like MMS1_N PF10433.9 CAR29270.1 - 4.1e-72 243.4 1.1 2.8e-69 234.0 0.2 3.2 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CAR29270.1 - 1.3e-50 172.5 0.1 7.2e-50 170.1 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region BBS2_N PF14781.6 CAR29270.1 - 0.13 12.2 1.1 8.8 6.3 0.0 3.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Gsf2 PF11055.8 CAR29271.1 - 4.2e-169 562.2 0.1 5.2e-169 561.9 0.1 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 KCH PF16944.5 CAR29272.1 - 2.6e-94 315.7 24.1 3.3e-94 315.4 24.1 1.1 1 0 0 1 1 1 1 Fungal potassium channel BSMAP PF12280.8 CAR29272.1 - 1.1 9.4 5.8 23 5.1 1.2 2.7 2 1 0 3 3 3 0 Brain specific membrane anchored protein NRDE-2 PF08424.10 CAR29274.1 - 0.084 12.0 1.2 3.8 6.5 0.2 2.5 1 1 0 2 2 2 0 NRDE-2, necessary for RNA interference RRM_1 PF00076.22 CAR29275.1 - 7.9e-27 92.9 0.3 4.4e-16 58.5 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR29275.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif AMPK1_CBM PF16561.5 CAR29276.1 - 6e-14 52.0 0.1 1.2e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase ANAPC1 PF12859.7 CAR29277.1 - 1.4e-09 38.6 0.7 8.8e-09 36.0 0.7 2.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 CAR29277.1 - 0.55 10.8 8.5 16 6.1 1.4 4.8 5 0 0 5 5 5 0 Proteasome/cyclosome repeat PS_Dcarbxylase PF02666.15 CAR29278.1 - 4.1e-69 232.2 0.0 7e-69 231.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 CAR29278.1 - 0.076 12.7 0.0 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 MNLL subunit dCMP_cyt_deam_1 PF00383.23 CAR29279.1 - 6.4e-27 93.4 1.9 1.1e-26 92.6 1.9 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CAR29279.1 - 2.4e-15 56.5 0.1 4.4e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CAR29279.1 - 0.058 13.5 1.1 0.12 12.5 0.5 1.8 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 Arc_C PF18162.1 CAR29279.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Arc C-lobe APOBEC_N PF08210.11 CAR29279.1 - 0.43 10.4 2.4 0.96 9.3 2.4 1.7 1 1 0 1 1 1 0 APOBEC-like N-terminal domain FAA_hydrolase PF01557.18 CAR29280.1 - 8.9e-48 162.8 0.0 1.1e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family bZIP_1 PF00170.21 CAR29281.1 - 2.5e-06 27.5 4.1 6.3e-06 26.2 4.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.8 CAR29281.1 - 9.6e-06 25.9 1.4 9.6e-06 25.9 1.4 4.0 3 1 1 4 4 4 1 Aft1 osmotic stress response (OSM) domain Aft1_HRA PF11786.8 CAR29281.1 - 0.0023 18.2 8.2 0.0023 18.2 8.2 4.1 3 1 1 4 4 4 1 Aft1 HRA domain bZIP_2 PF07716.15 CAR29281.1 - 0.011 15.8 6.4 0.011 15.8 6.4 2.6 3 0 0 3 3 3 0 Basic region leucine zipper DNA_RNApol_7kD PF03604.13 CAR29282.1 - 1e-16 60.2 1.7 1.4e-16 59.9 1.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 CAR29282.1 - 0.0039 16.8 0.8 1.5 8.5 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 CAR29282.1 - 0.0072 16.3 0.4 0.01 15.9 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 CAR29282.1 - 0.012 15.6 0.2 0.012 15.6 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIS_C PF01096.18 CAR29282.1 - 0.019 14.8 2.7 3.8 7.4 0.5 2.4 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) zinc-ribbons_6 PF07191.12 CAR29282.1 - 0.019 14.9 0.4 0.025 14.6 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbons MCM_OB PF17207.3 CAR29282.1 - 0.026 14.4 0.2 0.027 14.3 0.2 1.1 1 0 0 1 1 1 0 MCM OB domain IrmA PF18673.1 CAR29282.1 - 0.076 13.2 0.0 0.084 13.0 0.0 1.1 1 0 0 1 1 1 0 interleukin receptor mimic protein A DUF2197 PF09963.9 CAR29282.1 - 0.089 13.1 2.0 7.7 6.9 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF4428 PF14471.6 CAR29282.1 - 0.092 12.7 1.5 1.7 8.6 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) Zn_ribbon_SprT PF17283.2 CAR29282.1 - 0.1 12.5 2.5 0.15 11.9 1.9 1.7 1 1 2 3 3 3 0 SprT-like zinc ribbon domain Ribosomal_L40e PF01020.17 CAR29282.1 - 0.11 12.5 2.5 0.15 12.0 2.5 1.3 1 0 0 1 1 1 0 Ribosomal L40e family FYDLN_acid PF09538.10 CAR29282.1 - 0.15 12.7 0.4 0.18 12.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zinc_ribbon_10 PF10058.9 CAR29282.1 - 0.17 11.6 2.0 0.52 10.1 0.1 2.0 1 1 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein Zn-ribbon_8 PF09723.10 CAR29282.1 - 0.24 11.6 3.3 0.79 9.9 3.3 1.9 1 1 1 2 2 2 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 CAR29282.1 - 0.26 11.8 2.9 3.7 8.1 0.6 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Rubredoxin_2 PF18073.1 CAR29282.1 - 0.52 10.1 2.7 9.7 6.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_4 PF13717.6 CAR29282.1 - 0.63 10.0 3.9 6.3 6.8 4.0 2.4 1 1 1 2 2 2 0 zinc-ribbon domain Ribosomal_L44 PF00935.19 CAR29282.1 - 1.4 9.5 4.8 13 6.3 0.7 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 GTP_EFTU PF00009.27 CAR29287.1 - 7e-57 192.1 0.0 1.3e-56 191.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CAR29287.1 - 2.7e-14 52.9 0.2 9.3e-14 51.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CAR29287.1 - 5.1e-12 46.0 0.0 1.5e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CAR29287.1 - 2.6e-09 37.0 0.1 1.1e-07 31.8 0.0 2.5 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_IV PF03764.18 CAR29287.1 - 8.3e-05 22.4 0.0 0.00049 19.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 CAR29287.1 - 0.0058 16.7 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Cnd1_N PF12922.7 CAR29287.1 - 0.036 13.9 0.0 0.083 12.7 0.0 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Chs7 PF12271.8 CAR29288.1 - 5.8e-111 370.5 18.8 6.6e-111 370.3 18.8 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2583 PF10762.9 CAR29288.1 - 2.4 8.6 11.1 1.6 9.2 1.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) Ribosomal_L44 PF00935.19 CAR29289.1 - 3.2e-35 120.4 11.8 5.1e-35 119.8 11.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Pkinase PF00069.25 CAR29290.1 - 8.9e-61 205.6 0.3 1e-41 143.1 0.2 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29290.1 - 4.5e-27 95.0 0.4 1.5e-20 73.6 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR29290.1 - 4.4e-05 22.6 0.2 4.4e-05 22.6 0.2 1.9 2 1 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CAR29290.1 - 0.057 12.5 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CAR29290.1 - 0.061 12.1 0.0 0.061 12.1 0.0 2.6 2 0 0 2 2 2 0 Fungal protein kinase DUF4407 PF14362.6 CAR29290.1 - 0.6 9.4 30.6 0.16 11.3 20.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) SAPS PF04499.15 CAR29290.1 - 10 4.8 10.6 11 4.7 9.5 1.5 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein Far-17a_AIG1 PF04750.14 CAR29291.1 - 1.7e-10 40.6 3.5 1.3e-09 37.6 3.5 1.9 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein SieB PF14163.6 CAR29291.1 - 0.15 11.5 0.5 0.5 9.9 0.6 1.8 2 0 0 2 2 2 0 Super-infection exclusion protein B MSC PF09402.10 CAR29291.1 - 0.25 10.8 2.0 0.4 10.1 2.0 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain EMC3_TMCO1 PF01956.16 CAR29291.1 - 0.26 11.0 0.6 0.51 10.1 0.6 1.5 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Hamartin PF04388.12 CAR29292.1 - 9.2 4.8 10.4 12 4.4 10.4 1.1 1 0 0 1 1 1 0 Hamartin protein Ammonium_transp PF00909.21 CAR29293.1 - 6.6e-125 416.9 28.6 7.6e-125 416.7 28.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Inhibitor_I9 PF05922.16 CAR29294.1 - 0.025 15.2 0.2 0.23 12.1 0.2 2.3 1 1 0 1 1 1 0 Peptidase inhibitor I9 Prefoldin_2 PF01920.20 CAR29295.1 - 1.8e-22 79.3 12.3 2.1e-22 79.1 12.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit RSS_P20 PF11757.8 CAR29295.1 - 0.017 15.6 2.7 0.018 15.4 0.9 1.8 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DivIC PF04977.15 CAR29295.1 - 0.021 14.6 1.7 0.021 14.6 1.7 2.1 1 1 1 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 CAR29295.1 - 0.11 12.8 1.2 0.11 12.8 1.2 2.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 CAR29295.1 - 0.16 11.3 1.5 0.24 10.7 1.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Nas2_N PF18265.1 CAR29295.1 - 0.17 11.8 5.8 1.8 8.5 0.5 2.6 3 0 0 3 3 3 0 Nas2 N_terminal domain Seryl_tRNA_N PF02403.22 CAR29295.1 - 0.23 11.7 7.8 0.73 10.1 1.4 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.19 CAR29295.1 - 0.35 8.7 6.0 0.43 8.4 6.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XhlA PF10779.9 CAR29295.1 - 0.71 10.1 5.2 0.12 12.6 1.3 1.7 2 0 0 2 2 2 0 Haemolysin XhlA ABC_tran_CTD PF16326.5 CAR29295.1 - 1.9 8.8 11.4 1.2 9.5 4.4 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain APG6_N PF17675.1 CAR29295.1 - 4.1 7.9 15.4 46 4.6 15.4 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 CAR29295.1 - 8.4 6.9 7.2 48 4.5 7.2 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Aminotran_1_2 PF00155.21 CAR29296.1 - 6e-16 58.6 0.0 1.4e-15 57.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CAR29296.1 - 0.092 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase A_deaminase PF00962.22 CAR29298.1 - 5.8e-92 308.5 0.0 6.5e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Ectatomin PF06457.11 CAR29298.1 - 0.28 11.1 0.6 27 4.8 0.2 2.4 2 0 0 2 2 2 0 Ectatomin Pkinase PF00069.25 CAR29299.1 - 1.9e-23 83.2 0.0 3.2e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29299.1 - 2.1e-12 46.9 0.0 3.8e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR29299.1 - 4.4e-09 35.6 1.5 4.6e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CAR29299.1 - 0.0009 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-AN1 PF01428.16 CAR29300.1 - 1.5e-09 37.9 13.1 2.4e-09 37.2 13.1 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger WLM PF08325.10 CAR29301.1 - 1e-61 208.4 0.0 1.2e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 CAR29301.1 - 0.017 15.2 0.1 0.031 14.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 INSIG PF07281.12 CAR29302.1 - 1.3e-17 64.1 11.1 1.1e-16 61.1 5.4 3.1 1 1 2 3 3 3 2 Insulin-induced protein (INSIG) Phage_holin_4_2 PF04020.13 CAR29302.1 - 0.03 15.0 2.1 0.03 15.0 2.1 1.8 2 0 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV VIT1 PF01988.19 CAR29302.1 - 0.29 11.0 4.2 0.14 12.0 1.9 1.7 1 1 1 2 2 2 0 VIT family Endosulfine PF04667.17 CAR29303.1 - 8.4e-33 112.4 0.3 1.2e-32 111.9 0.3 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Ntox33 PF15533.6 CAR29303.1 - 0.11 12.9 0.8 0.32 11.5 0.8 1.7 1 1 0 1 1 1 0 Bacterial toxin 33 Peptidase_M14 PF00246.24 CAR29304.1 - 3.3e-74 250.3 0.1 3.9e-74 250.0 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Pga1 PF10333.9 CAR29305.1 - 3.8e-66 222.3 2.0 4.5e-66 222.0 2.0 1.0 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Proteasom_Rpn13 PF04683.13 CAR29305.1 - 0.014 15.9 0.1 0.048 14.2 0.0 1.8 2 0 0 2 2 2 0 Proteasome complex subunit Rpn13 ubiquitin receptor DUF4175 PF13779.6 CAR29306.1 - 0.49 8.2 4.6 0.67 7.8 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Arginase PF00491.21 CAR29307.1 - 2e-90 303.1 0.0 2.3e-90 302.9 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 CAR29307.1 - 0.025 14.8 0.3 0.044 14.0 0.3 1.4 1 0 0 1 1 1 0 UPF0489 domain PH PF00169.29 CAR29308.1 - 0.086 13.4 1.2 0.51 10.9 0.2 2.6 2 1 0 2 2 2 0 PH domain Suf PF05843.14 CAR29308.1 - 0.42 10.5 5.3 0.72 9.8 5.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2009 PF09418.10 CAR29309.1 - 5.7e-207 688.3 2.0 6.8e-207 688.0 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 CAR29309.1 - 2.2e-05 24.5 9.5 5.2e-05 23.3 9.5 1.7 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 CAR29309.1 - 0.0019 18.4 7.7 0.0048 17.1 7.7 1.7 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 CAR29309.1 - 0.06 13.6 4.6 0.17 12.1 4.6 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 CAR29309.1 - 0.53 10.2 7.8 0.97 9.3 7.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Actin PF00022.19 CAR29310.1 - 1.2e-110 369.9 0.0 5.8e-110 367.7 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CAR29310.1 - 0.16 10.8 0.0 0.67 8.7 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein UPRTase PF14681.6 CAR29311.1 - 3.6e-76 255.2 0.0 4.5e-76 254.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CAR29311.1 - 0.0045 16.5 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain LSM PF01423.22 CAR29312.1 - 7.9e-21 73.5 0.2 1.1e-20 73.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CAR29312.1 - 0.011 15.3 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 Hfq protein CAP_GLY PF01302.25 CAR29313.1 - 6.9e-17 61.2 0.9 1.1e-16 60.5 0.6 1.5 2 0 0 2 2 2 1 CAP-Gly domain Ubiquitin_2 PF14560.6 CAR29313.1 - 4.8e-05 23.7 0.0 9.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain SAS4 PF15460.6 CAR29313.1 - 0.028 14.5 0.3 0.058 13.5 0.2 1.6 1 1 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 PGA2 PF07543.12 CAR29314.1 - 4.1e-11 43.0 3.0 2.9e-06 27.3 0.0 2.1 1 1 1 2 2 2 2 Protein trafficking PGA2 DUF1643 PF07799.12 CAR29314.1 - 0.095 12.9 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) RNA_pol_3_Rpc31 PF11705.8 CAR29315.1 - 1.9e-56 191.9 13.6 2.5e-56 191.5 13.6 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF4820 PF16091.5 CAR29315.1 - 4.3 6.6 8.8 2 7.7 6.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) C2 PF00168.30 CAR29316.1 - 3.9e-05 23.9 0.0 7.5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 C2 domain THOC2_N PF16134.5 CAR29317.1 - 5.6e-173 577.0 7.2 5.6e-173 577.0 7.2 2.1 3 0 0 3 3 3 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 CAR29317.1 - 3.5e-42 144.6 6.8 8e-31 107.3 3.2 4.4 3 1 1 4 4 4 2 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 CAR29317.1 - 3.1e-22 78.4 0.2 8.4e-22 77.0 0.2 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit SF3b10 PF07189.11 CAR29318.1 - 1.9e-26 91.9 1.4 2.2e-26 91.8 1.4 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) CAP_N PF01213.19 CAR29320.1 - 7.4e-112 373.9 1.0 7.4e-112 373.9 1.0 1.7 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CAR29320.1 - 3.9e-58 195.5 0.2 5.5e-58 195.0 0.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal BshC PF10079.9 CAR29320.1 - 0.15 10.7 0.0 0.34 9.6 0.0 1.5 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC TBCC PF07986.12 CAR29320.1 - 0.26 11.0 2.0 0.72 9.6 2.0 1.7 1 1 0 1 1 1 0 Tubulin binding cofactor C S4 PF01479.25 CAR29321.1 - 1e-14 54.0 0.0 2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 CAR29321.1 - 0.04 13.7 0.0 0.099 12.5 0.0 1.6 1 0 0 1 1 1 0 S4 domain FRB_dom PF08771.11 CAR29321.1 - 0.098 13.1 1.6 0.25 11.8 0.1 2.4 2 1 1 3 3 3 0 FKBP12-rapamycin binding domain GN3L_Grn1 PF08701.11 CAR29321.1 - 0.16 12.1 2.8 0.5 10.5 2.8 1.8 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Eaf7 PF07904.13 CAR29322.1 - 8.4e-35 119.4 2.3 8.4e-35 119.4 2.3 3.1 3 2 0 3 3 3 1 Chromatin modification-related protein EAF7 YL1 PF05764.13 CAR29322.1 - 0.017 15.3 17.5 0.017 15.3 17.5 2.1 1 1 1 2 2 2 0 YL1 nuclear protein Macoilin PF09726.9 CAR29322.1 - 0.073 11.6 17.1 0.082 11.5 17.1 1.0 1 0 0 1 1 1 0 Macoilin family FKBP_C PF00254.28 CAR29323.1 - 2.4e-33 114.3 0.0 2.9e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ADH_zinc_N PF00107.26 CAR29324.1 - 2.7e-11 43.6 0.0 5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CAR29324.1 - 4.8e-07 29.6 0.1 7e-06 25.9 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CAR29324.1 - 0.082 12.8 0.1 0.21 11.5 0.1 1.7 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase PIR PF00399.19 CAR29325.1 - 1.1e-05 24.8 4.9 1.1e-05 24.8 4.9 2.8 3 0 0 3 3 3 1 Yeast PIR protein repeat MGC-24 PF05283.11 CAR29325.1 - 0.12 12.9 4.6 0.14 12.6 4.6 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin BASP1 PF05466.12 CAR29325.1 - 1.7 8.6 18.5 2 8.4 18.5 1.0 1 0 0 1 1 1 0 Brain acid soluble protein 1 (BASP1 protein) V-SNARE PF05008.15 CAR29326.1 - 1.6e-06 28.4 1.3 24 5.4 0.0 7.2 9 1 1 10 10 10 0 Vesicle transport v-SNARE protein N-terminus RICTOR_M PF14666.6 CAR29326.1 - 2.3e-06 27.3 0.2 37 4.2 0.0 5.3 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR, middle domain DLP_helical PF18709.1 CAR29326.1 - 4.4e-05 22.8 0.3 3.4 6.8 0.0 3.8 1 1 3 4 4 4 4 Dynamin-like helical domain Baculo_PEP_C PF04513.12 CAR29326.1 - 0.0015 18.6 16.6 3.7 7.6 3.6 5.9 4 2 2 6 6 6 1 Baculovirus polyhedron envelope protein, PEP, C terminus ATP-cone PF03477.16 CAR29326.1 - 0.015 15.9 0.0 4e+02 1.7 0.0 5.4 5 1 0 5 5 5 0 ATP cone domain Sigma54_DBD PF04552.13 CAR29326.1 - 0.078 12.7 0.3 46 3.7 0.0 4.2 5 0 0 5 5 5 0 Sigma-54, DNA binding domain DUF4549 PF15082.6 CAR29326.1 - 0.11 12.3 0.1 75 3.1 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF4549) HsbA PF12296.8 CAR29326.1 - 0.11 12.9 3.3 77 3.8 0.1 5.3 5 0 0 5 5 5 0 Hydrophobic surface binding protein A Leptin PF02024.15 CAR29326.1 - 0.12 12.2 9.4 86 2.9 0.0 6.0 5 5 1 6 6 6 0 Leptin Tup_N PF08581.10 CAR29326.1 - 0.14 12.5 5.0 1.4e+02 2.9 0.0 5.3 5 0 0 5 5 5 0 Tup N-terminal Staphylcoagulse PF04022.12 CAR29327.1 - 3.3e-13 48.9 12.5 0.79 9.3 0.1 8.2 7 0 0 7 7 7 6 Staphylocoagulase repeat FliC PF12445.8 CAR29327.1 - 0.0028 18.0 48.8 0.014 15.7 6.8 6.8 3 2 1 5 5 5 2 Flagellin protein Turandot PF07240.11 CAR29327.1 - 0.0043 17.0 0.0 29 4.7 0.0 3.4 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot DUF2140 PF09911.9 CAR29327.1 - 0.0087 15.6 0.6 1.8 8.1 0.1 3.1 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2140) OstA PF03968.14 CAR29327.1 - 0.14 12.4 3.4 68 3.7 0.1 3.8 3 0 0 3 3 3 0 OstA-like protein MORN_2 PF07661.13 CAR29327.1 - 0.18 12.1 1.1 2e+02 2.7 0.0 3.9 3 0 0 3 3 3 0 MORN repeat variant DUF3327 PF11806.8 CAR29327.1 - 0.24 12.1 0.0 1.8e+02 2.8 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3327) RPS31 PF17067.5 CAR29327.1 - 0.96 9.6 6.4 18 5.5 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein S31e Adeno_E3_CR1 PF02440.15 CAR29327.1 - 5.7 6.8 11.1 9.3 6.1 0.1 5.7 6 3 0 6 6 6 0 Adenovirus E3 region protein CR1 NDT80_PhoG PF05224.12 CAR29329.1 - 1.7e-62 210.9 0.0 3e-62 210.1 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family GNAT_acetyltr_2 PF13718.6 CAR29330.1 - 4e-99 330.6 0.4 1.6e-98 328.6 0.0 2.2 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CAR29330.1 - 3.8e-93 311.5 6.1 6.5e-93 310.8 6.1 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CAR29330.1 - 2.3e-64 216.5 0.1 1.2e-63 214.2 0.0 2.3 2 1 1 3 3 3 1 Helicase DUF1726 PF08351.11 CAR29330.1 - 2.9e-34 116.9 1.2 4.3e-34 116.3 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_22 PF13401.6 CAR29330.1 - 0.00044 20.5 0.0 0.19 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CAR29330.1 - 0.00065 19.5 0.0 0.099 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Tom22 PF04281.13 CAR29331.1 - 8e-51 171.5 0.3 9e-51 171.3 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CDP-OH_P_transf PF01066.21 CAR29332.1 - 1.5e-09 38.5 0.0 1.5e-09 38.5 0.0 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FeS_assembly_P PF01883.19 CAR29333.1 - 3.8e-09 36.6 0.0 6.2e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein PRK PF00485.18 CAR29334.1 - 7.8e-06 25.8 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CAR29334.1 - 2.5e-05 24.8 0.0 0.00014 22.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 CAR29334.1 - 6.5e-05 22.8 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase CPT PF07931.12 CAR29334.1 - 0.00014 21.7 0.0 0.0014 18.5 0.0 2.2 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 CAR29334.1 - 0.019 15.1 0.0 0.041 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 CAR29334.1 - 0.051 13.0 0.2 0.54 9.7 0.0 2.0 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 CAR29334.1 - 0.056 13.7 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CAR29334.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CAR29334.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DSPc PF00782.20 CAR29335.1 - 1.3e-09 38.0 0.0 3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR29335.1 - 0.0041 16.7 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CAR29335.1 - 0.022 14.9 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CAR29335.1 - 0.079 12.9 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family AD PF09793.9 CAR29336.1 - 1.3e-23 82.9 0.1 2.2e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain LSM14 PF12701.7 CAR29336.1 - 0.076 13.1 0.4 0.3 11.2 0.4 1.9 1 1 0 1 1 1 0 Scd6-like Sm domain Get5_C PF18514.1 CAR29336.1 - 0.27 11.0 1.7 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Get5 C-terminal domain RhoGEF67_u1 PF16615.5 CAR29336.1 - 0.48 11.0 1.9 0.95 10.0 1.9 1.4 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 N1221 PF07923.13 CAR29337.1 - 1.9e-70 237.4 1.9 4.2e-70 236.2 1.9 1.6 1 0 0 1 1 1 1 N1221-like protein DUF3402 PF11882.8 CAR29337.1 - 4.2e-50 171.2 18.1 8.1e-28 97.7 4.4 4.3 2 1 1 3 3 3 2 Domain of unknown function (DUF3402) FerA PF08165.11 CAR29337.1 - 0.073 13.0 1.0 0.22 11.5 1.0 1.8 1 0 0 1 1 1 0 FerA (NUC095) domain GCP_C_terminal PF04130.13 CAR29338.1 - 8.3e-32 110.9 3.8 8.3e-32 110.9 3.8 2.3 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CAR29338.1 - 7.1e-31 108.0 12.8 1.4e-28 100.4 6.9 2.4 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal BEN PF10523.9 CAR29338.1 - 0.07 13.4 0.0 0.19 12.0 0.0 1.7 1 0 0 1 1 1 0 BEN domain MFS_1 PF07690.16 CAR29339.1 - 2.7e-23 82.5 42.8 5.9e-23 81.4 42.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CAR29339.1 - 6.7e-08 31.5 9.7 6.7e-08 31.5 9.7 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.24 CAR29339.1 - 5.8e-06 25.4 6.3 5.8e-06 25.4 6.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 CAR29339.1 - 8.5e-06 24.9 2.2 8.5e-06 24.9 2.2 2.2 2 0 0 2 2 2 1 MFS_1 like family Gar1 PF04410.14 CAR29340.1 - 2.2e-43 147.7 1.1 2.2e-43 147.7 1.1 2.2 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region MutS_V PF00488.21 CAR29341.1 - 3.5e-64 216.3 0.0 7.3e-64 215.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CAR29341.1 - 1.7e-33 116.5 3.8 5.1e-33 114.9 3.8 1.9 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CAR29341.1 - 1.7e-24 86.2 0.0 4.5e-24 84.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CAR29341.1 - 7.7e-11 42.4 0.0 1.1e-09 38.7 0.0 2.8 2 0 0 2 2 2 1 MutS domain II DUF2704 PF10866.8 CAR29341.1 - 0.013 15.4 0.1 0.028 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) Vault PF01505.18 CAR29341.1 - 0.057 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Major Vault Protein repeat domain N-SET PF11764.8 CAR29342.1 - 3.2e-50 170.6 0.6 3.2e-50 170.6 0.6 2.8 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 CAR29342.1 - 2.3e-19 68.8 0.0 6.2e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 CAR29342.1 - 1.8e-17 64.3 0.1 1.8e-17 64.3 0.1 3.3 2 2 1 3 3 3 1 SET domain ORC6 PF05460.13 CAR29343.1 - 3.9e-90 302.7 6.8 4.4e-90 302.5 6.8 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Presenilin PF01080.17 CAR29343.1 - 3 6.5 4.0 4 6.1 4.0 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_L35p PF01632.19 CAR29344.1 - 2.2e-13 50.5 6.3 3e-13 50.1 6.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 TPR_2 PF07719.17 CAR29345.1 - 6.1e-21 72.8 35.5 0.0015 18.5 0.7 11.3 9 2 2 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 CAR29345.1 - 5e-20 70.4 41.2 5.1e-06 26.1 2.2 10.6 10 2 1 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 CAR29345.1 - 2.4e-14 53.7 13.4 0.06 14.0 0.1 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 CAR29345.1 - 1.1e-11 43.9 34.2 0.0055 16.8 0.4 8.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 CAR29345.1 - 1.2e-11 44.7 17.9 0.0056 17.0 0.2 7.8 6 4 2 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 CAR29345.1 - 1.3e-11 43.9 25.7 0.00011 21.8 0.2 8.1 7 1 1 8 8 8 5 TPR repeat TPR_19 PF14559.6 CAR29345.1 - 7e-11 42.5 21.0 0.00044 20.7 1.4 6.5 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAR29345.1 - 1.7e-08 34.6 13.9 0.42 11.6 0.0 8.2 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAR29345.1 - 2.9e-07 30.4 13.7 0.00023 21.3 0.1 7.0 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAR29345.1 - 5.3e-06 26.5 0.5 1.1 9.4 0.0 5.0 5 1 0 6 6 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CAR29345.1 - 4.1e-05 23.1 2.0 0.00075 19.0 0.9 2.9 2 1 0 2 2 2 1 MalT-like TPR region ANAPC3 PF12895.7 CAR29345.1 - 5.1e-05 23.4 15.5 0.14 12.4 2.2 4.4 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CAR29345.1 - 0.00065 19.5 13.9 1.1 9.4 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 CAR29345.1 - 0.0093 16.0 0.5 0.0093 16.0 0.5 3.3 3 0 0 3 3 3 1 Exonuclease VII small subunit HrpB1_HrpK PF09613.10 CAR29345.1 - 0.045 13.4 0.1 1.2 8.8 0.1 2.7 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) PPTA PF01239.22 CAR29345.1 - 0.059 13.1 0.0 1.4 8.8 0.0 3.0 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat Fis1_TPR_C PF14853.6 CAR29345.1 - 0.12 12.4 1.2 8.4 6.6 0.1 3.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Gti1_Pac2 PF09729.9 CAR29345.1 - 0.18 11.9 1.8 0.38 10.8 1.8 1.6 1 0 0 1 1 1 0 Gti1/Pac2 family SPO22 PF08631.10 CAR29345.1 - 0.24 10.9 4.9 0.32 10.4 0.2 3.0 3 1 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_20 PF14561.6 CAR29345.1 - 1.1 9.7 8.4 0.93 9.9 1.1 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CAR29345.1 - 1.5 8.8 12.8 4.4 7.3 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 CAR29345.1 - 8.6 6.0 8.6 1.6 8.4 0.1 3.7 4 1 0 4 4 4 0 26S proteasome subunit RPN7 MTCP1 PF08991.10 CAR29346.1 - 3.1e-05 24.1 2.7 4.6e-05 23.6 2.7 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 CAR29346.1 - 0.00041 20.4 9.2 0.00066 19.7 9.2 1.3 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 CAR29346.1 - 0.005 17.1 3.3 0.0069 16.7 3.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DAGK_cat PF00781.24 CAR29347.1 - 8.9e-09 35.0 0.0 1.7e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain YqzH PF14164.6 CAR29347.1 - 0.083 13.0 0.0 0.52 10.4 0.0 2.3 4 0 0 4 4 4 0 YqzH-like protein zf-primase PF09329.11 CAR29348.1 - 1.5e-14 53.5 1.3 2.6e-14 52.7 1.3 1.4 1 0 0 1 1 1 1 Primase zinc finger DUF5088 PF17008.5 CAR29348.1 - 0.013 15.3 0.6 0.032 14.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5088) tRNA_anti-codon PF01336.25 CAR29348.1 - 0.017 15.1 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain TPR_MLP1_2 PF07926.12 CAR29349.1 - 2.8e-28 98.6 29.7 2.8e-28 98.6 29.7 19.1 5 4 16 22 22 22 7 TPR/MLP1/MLP2-like protein ubiquitin PF00240.23 CAR29350.1 - 3.7e-34 116.3 0.6 4.9e-34 115.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CAR29350.1 - 2.2e-30 104.3 10.2 3.3e-30 103.7 10.2 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CAR29350.1 - 1.9e-16 59.7 0.7 3e-16 59.0 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAR29350.1 - 2e-05 24.9 0.1 7.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CAR29350.1 - 0.0037 17.6 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CAR29350.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAR29350.1 - 0.0048 17.0 0.1 0.01 16.0 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CAR29350.1 - 0.014 15.4 1.0 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CAR29350.1 - 0.024 15.2 0.1 0.031 14.8 0.1 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CAR29350.1 - 0.079 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Response_reg PF00072.24 CAR29351.1 - 1.3e-28 99.4 0.8 3.1e-28 98.2 0.8 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 CAR29351.1 - 6.1e-26 91.1 0.4 4.9e-20 72.1 0.1 2.8 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CAR29351.1 - 7.4e-12 45.1 0.2 2.3e-11 43.5 0.2 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 CAR29351.1 - 0.00086 19.6 0.3 0.32 11.4 0.0 2.6 2 0 0 2 2 2 2 HAMP domain HATPase_c_3 PF13589.6 CAR29351.1 - 0.05 13.4 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PTR2 PF00854.21 CAR29353.1 - 3e-101 339.1 5.2 9.7e-101 337.4 5.2 1.7 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 CAR29353.1 - 9.4e-09 34.7 24.7 5.8e-08 32.0 22.5 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Aa_trans PF01490.18 CAR29354.1 - 3.6e-24 85.2 32.0 3.6e-24 85.2 32.0 2.2 2 1 0 2 2 2 1 Transmembrane amino acid transporter protein Pantoate_ligase PF02569.15 CAR29355.1 - 1.9e-89 299.4 0.0 2.2e-89 299.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Acetyltransf_1 PF00583.25 CAR29356.1 - 3.4e-19 69.2 0.0 4.7e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CAR29356.1 - 1.5e-12 47.6 0.0 2.1e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CAR29356.1 - 4.7e-06 26.9 0.0 7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CAR29356.1 - 0.0033 16.9 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 CAR29356.1 - 0.0065 16.6 0.0 0.0097 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CAR29356.1 - 0.031 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CAR29356.1 - 0.089 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 CAR29356.1 - 0.12 12.4 0.0 0.76 9.9 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Leuk-A4-hydro_C PF09127.11 CAR29357.1 - 0.062 13.4 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal UCH PF00443.29 CAR29358.1 - 8.2e-63 212.3 2.2 1.2e-62 211.8 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CAR29358.1 - 3.4e-22 79.5 0.3 6.4e-22 78.5 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CAR29358.1 - 3.8e-06 27.4 0.0 9.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 CAR29358.1 - 0.0059 16.3 0.7 0.0059 16.3 0.7 1.8 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger SRP_TPR_like PF17004.5 CAR29358.1 - 0.026 14.5 0.3 0.063 13.3 0.3 1.6 1 0 0 1 1 1 0 Putative TPR-like repeat DUF4428 PF14471.6 CAR29358.1 - 0.074 13.0 1.7 0.28 11.2 1.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) MRNIP PF15749.5 CAR29358.1 - 0.092 13.5 1.8 0.96 10.2 0.6 2.7 2 0 0 2 2 2 0 MRN-interacting protein CW_binding_1 PF01473.20 CAR29358.1 - 0.49 10.8 4.5 1.9 9.0 4.5 2.0 1 0 0 1 1 1 0 Putative cell wall binding repeat Zn-ribbon_8 PF09723.10 CAR29358.1 - 0.84 9.8 2.9 19 5.5 0.4 2.8 2 0 0 2 2 2 0 Zinc ribbon domain BSD PF03909.17 CAR29359.1 - 1.8e-14 53.5 3.1 2.8e-14 52.8 0.1 2.7 3 0 0 3 3 3 1 BSD domain Y_phosphatase2 PF03162.13 CAR29360.1 - 6.3e-54 182.0 1.2 9.1e-54 181.5 1.2 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CAR29360.1 - 0.052 13.5 0.0 0.059 13.3 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family Asp_protease PF09668.10 CAR29361.1 - 1.6e-51 173.3 0.1 2.3e-51 172.8 0.1 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CAR29361.1 - 7.6e-21 74.5 0.1 1.5e-20 73.5 0.1 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CAR29361.1 - 6.2e-10 39.6 0.6 2.1e-09 37.9 0.1 2.2 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.31 CAR29361.1 - 3.3e-08 33.3 0.1 1.1e-07 31.6 0.1 1.9 2 0 0 2 2 2 1 UBA/TS-N domain RVP PF00077.20 CAR29361.1 - 0.00024 21.4 0.1 0.00078 19.7 0.1 1.9 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 CAR29361.1 - 0.011 15.5 0.0 0.026 14.3 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease HhH-GPD PF00730.25 CAR29362.1 - 1.2e-10 41.8 0.0 2.1e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein COX15-CtaA PF02628.15 CAR29363.1 - 5.9e-119 396.9 0.9 7e-119 396.7 0.9 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF4149 PF13664.6 CAR29363.1 - 0.58 10.5 6.7 0.82 10.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) 7TMR-DISM_7TM PF07695.11 CAR29363.1 - 4.4 7.1 10.1 0.17 11.7 0.4 2.8 2 1 1 3 3 3 0 7TM diverse intracellular signalling DUF747 PF05346.11 CAR29364.1 - 6.1e-80 269.1 21.7 1.1e-79 268.3 21.7 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF2200 PF09966.9 CAR29364.1 - 0.055 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) DUF2150 PF09920.9 CAR29364.1 - 0.21 11.5 0.4 1.8 8.5 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2150) RPAP2_Rtr1 PF04181.13 CAR29365.1 - 3.4e-17 62.5 0.5 7.8e-17 61.4 0.5 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family Complex1_LYR PF05347.15 CAR29366.1 - 0.0061 16.6 0.9 0.0061 16.6 0.9 2.8 4 0 0 4 4 4 1 Complex 1 protein (LYR family) Ras PF00071.22 CAR29367.1 - 2.1e-50 170.5 0.0 2.7e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR29367.1 - 8.8e-17 61.4 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR29367.1 - 5.7e-08 32.4 0.1 7e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAR29367.1 - 0.00019 21.1 0.1 0.00039 20.0 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CAR29367.1 - 0.0016 18.4 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CAR29367.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 CAR29367.1 - 0.079 12.1 0.0 4.2 6.4 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit PRC2_HTH_1 PF18118.1 CAR29367.1 - 0.77 10.6 4.1 3.3 8.6 4.1 1.9 1 1 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain tRNA_bind PF01588.20 CAR29368.1 - 1.1e-16 60.7 0.4 1.7e-16 60.1 0.4 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain PITH PF06201.13 CAR29369.1 - 4.9e-38 130.7 0.0 6.2e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 PITH domain ALAD PF00490.21 CAR29370.1 - 1.1e-118 396.1 0.0 1.3e-118 395.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PALP PF00291.25 CAR29371.1 - 1.1e-58 199.0 0.0 1.3e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 CAR29371.1 - 5.8e-16 58.7 0.1 1.8e-10 41.1 0.1 2.6 2 0 0 2 2 2 2 CBS domain GHMP_kinases_C PF08544.13 CAR29371.1 - 0.081 13.3 0.0 0.61 10.5 0.0 2.3 2 0 0 2 2 2 0 GHMP kinases C terminal ComZ PF10815.8 CAR29372.1 - 0.00061 19.7 0.3 0.0011 18.9 0.3 1.4 1 0 0 1 1 1 1 ComZ AA_permease PF00324.21 CAR29373.1 - 3.1e-117 392.1 36.8 3.5e-117 391.9 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR29373.1 - 3.4e-39 134.9 45.1 4.1e-39 134.6 45.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2448 PF10476.9 CAR29373.1 - 0.3 10.9 1.3 0.78 9.6 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) TFIIS_M PF07500.14 CAR29374.1 - 2.3e-24 86.0 3.0 2.3e-24 86.0 3.0 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CAR29374.1 - 1.5e-17 63.2 6.4 3e-17 62.2 6.4 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CAR29374.1 - 7.3e-11 41.9 2.2 2.5e-10 40.2 2.2 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain IML1 PF12257.8 CAR29374.1 - 0.44 9.6 5.0 0.91 8.6 0.2 2.1 2 0 0 2 2 2 0 Vacuolar membrane-associated protein Iml1 DUF5327 PF17261.2 CAR29374.1 - 0.64 10.8 11.8 0.21 12.4 4.5 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5327) Ndc1_Nup PF09531.10 CAR29374.1 - 2.2 6.9 8.2 2.8 6.5 8.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RRM_1 PF00076.22 CAR29375.1 - 4e-21 74.6 0.0 6.7e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 CAR29375.1 - 6.2e-10 38.5 1.2 1.3e-09 37.5 1.2 1.5 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.6 CAR29375.1 - 6e-08 33.0 0.7 1.5e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_occluded PF16842.5 CAR29375.1 - 0.0015 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RL PF17797.1 CAR29375.1 - 0.021 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 RL domain RRM_7 PF16367.5 CAR29375.1 - 0.14 12.3 0.0 0.42 10.8 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif CSTF2_hinge PF14327.6 CAR29376.1 - 5e-23 81.3 5.1 5e-23 81.3 5.1 2.6 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 CAR29376.1 - 1.9e-06 27.4 2.1 1.9e-06 27.4 2.1 2.5 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal PEMT PF04191.13 CAR29377.1 - 2.1e-59 198.4 10.5 3.7e-35 120.5 0.6 3.2 3 0 0 3 3 3 2 Phospholipid methyltransferase ICMT PF04140.14 CAR29377.1 - 3.3 8.2 7.5 2.7 8.5 0.4 3.2 3 1 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family RNase_PH PF01138.21 CAR29378.1 - 5.7e-17 62.5 0.1 1.1e-16 61.5 0.1 1.4 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Arrestin_N PF00339.29 CAR29379.1 - 7.9e-20 71.4 0.0 2.6e-19 69.7 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CAR29379.1 - 5.5e-11 43.1 0.7 4.2e-08 33.7 0.1 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Molydop_binding PF01568.21 CAR29379.1 - 0.1 12.6 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain RRM_1 PF00076.22 CAR29380.1 - 1.3e-42 143.4 1.3 6.8e-21 73.9 0.0 3.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR29380.1 - 0.002 18.2 0.0 2 8.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CAR29380.1 - 0.013 15.0 0.0 3.7 7.1 0.0 2.6 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR29380.1 - 0.05 13.6 0.0 2.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 CAR29380.1 - 0.13 12.2 0.0 9.7 6.3 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain Beta_helix PF13229.6 CAR29381.1 - 2.6 7.9 13.6 0.79 9.6 6.0 2.4 1 1 1 2 2 2 0 Right handed beta helix region DUF2046 PF09755.9 CAR29382.1 - 0.0018 17.6 0.1 0.0025 17.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) APC_N_CC PF16689.5 CAR29382.1 - 0.042 13.9 0.2 0.078 13.0 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain TFIIE_beta PF02186.15 CAR29382.1 - 0.14 12.5 0.3 0.24 11.7 0.3 1.4 1 0 0 1 1 1 0 TFIIE beta subunit core domain Ferric_reduct PF01794.19 CAR29383.1 - 1.7e-25 89.6 9.8 1.7e-25 89.6 9.8 3.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CAR29383.1 - 1.5e-19 70.1 0.0 3.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CAR29383.1 - 3.4e-18 66.2 0.0 5.5e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain MFS_1 PF07690.16 CAR29384.1 - 1.9e-15 56.7 31.7 4.9e-15 55.3 31.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR29384.1 - 2.3e-06 26.4 13.4 4.8e-06 25.3 13.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1240 PF06836.12 CAR29384.1 - 1.8 9.2 10.3 3.1 8.4 4.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) Metallophos PF00149.28 CAR29385.1 - 1.1e-08 35.9 7.0 1.1e-08 35.9 7.0 2.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Cu-oxidase_2 PF07731.14 CAR29386.1 - 5.2e-40 136.3 10.9 1.4e-37 128.5 1.3 3.7 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CAR29386.1 - 3.3e-36 123.9 0.3 3.3e-36 123.9 0.3 2.9 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 CAR29386.1 - 1.7e-31 109.5 3.2 1.1e-30 106.8 0.1 3.1 4 0 0 4 4 4 1 Multicopper oxidase LRR19-TM PF15176.6 CAR29386.1 - 0.042 13.9 0.6 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Reprolysin_3 PF13582.6 CAR29386.1 - 0.074 13.6 0.5 2.5 8.6 0.0 2.8 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Phosphoesterase PF04185.14 CAR29387.1 - 1e-36 126.9 5.1 1.7e-35 122.8 1.9 3.1 2 1 1 3 3 3 2 Phosphoesterase family Toxin_ToxA PF11584.8 CAR29387.1 - 3.9 7.5 6.7 1.2 9.2 2.0 2.1 2 0 0 2 2 2 0 Proteinaceous host-selective toxin ToxA SET PF00856.28 CAR29388.1 - 2.2e-10 41.2 0.1 6.9e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 SET domain Cofilin_ADF PF00241.20 CAR29389.1 - 7.7e-41 138.7 0.1 8.6e-41 138.5 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CBM_4_9 PF02018.17 CAR29389.1 - 0.026 14.8 0.5 0.045 14.0 0.2 1.4 2 0 0 2 2 2 0 Carbohydrate binding domain Pur_ac_phosph_N PF16656.5 CAR29389.1 - 0.069 13.7 0.8 3.4 8.3 0.0 2.2 1 1 1 2 2 2 0 Purple acid Phosphatase, N-terminal domain AA_permease_2 PF13520.6 CAR29392.1 - 9.4e-60 202.6 35.5 1.4e-59 202.1 35.5 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAR29392.1 - 1e-11 44.2 30.8 1.7e-11 43.4 30.8 1.2 1 1 0 1 1 1 1 Amino acid permease PalH PF08733.10 CAR29392.1 - 1.3 8.0 8.3 0.18 10.8 0.5 2.4 2 1 0 2 2 2 0 PalH/RIM21 ABC_membrane PF00664.23 CAR29393.1 - 1.4e-59 202.0 34.9 6.3e-41 140.8 11.5 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 CAR29393.1 - 9.5e-59 197.8 0.1 1.8e-34 119.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CAR29393.1 - 1.9e-09 37.3 5.3 3.5e-05 23.3 1.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CAR29393.1 - 8.2e-09 35.7 2.6 0.0088 15.9 0.2 3.7 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CAR29393.1 - 4.7e-08 33.8 7.0 5.1e-05 23.9 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 CAR29393.1 - 8.7e-07 28.6 2.0 0.0062 16.3 0.0 3.2 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAR29393.1 - 6.9e-06 26.1 0.0 0.084 12.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CAR29393.1 - 4.2e-05 23.6 0.3 0.013 15.5 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CAR29393.1 - 0.00013 21.9 0.0 2.5 7.8 0.0 3.4 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein T2SSE PF00437.20 CAR29393.1 - 0.00016 20.8 0.0 0.033 13.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 CAR29393.1 - 0.00021 21.7 0.0 0.61 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CAR29393.1 - 0.00021 21.6 0.0 0.7 10.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CAR29393.1 - 0.00071 18.9 0.0 1.4 8.1 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_15 PF13175.6 CAR29393.1 - 0.0009 19.1 11.4 0.016 14.9 0.5 2.8 3 0 0 3 3 2 2 AAA ATPase domain DUF87 PF01935.17 CAR29393.1 - 0.0011 19.2 0.8 0.82 9.7 0.1 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA PF00004.29 CAR29393.1 - 0.0011 19.4 0.1 2.3 8.6 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CAR29393.1 - 0.0014 18.2 2.3 0.41 10.1 0.0 2.9 3 0 0 3 3 2 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 CAR29393.1 - 0.0062 15.9 0.2 2.5 7.4 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.6 CAR29393.1 - 0.0097 15.6 0.2 7 6.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 CAR29393.1 - 0.018 14.8 0.0 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CAR29393.1 - 0.024 14.7 4.6 1.4 9.0 0.3 3.0 3 0 0 3 3 3 0 Dynamin family Guanylate_kin PF00625.21 CAR29393.1 - 0.082 12.6 0.1 2.6 7.7 0.0 2.7 2 0 0 2 2 2 0 Guanylate kinase AAA_33 PF13671.6 CAR29393.1 - 0.09 12.9 0.2 16 5.7 0.0 3.0 4 0 0 4 4 2 0 AAA domain cobW PF02492.19 CAR29393.1 - 0.11 12.1 0.9 4.8 6.7 0.2 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.6 CAR29393.1 - 0.19 12.1 0.1 4.2 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CAR29393.1 - 2.9 8.1 6.0 33 4.7 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase RRM_1 PF00076.22 CAR29394.1 - 2.6e-21 75.2 3.0 5.5e-12 45.3 0.2 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CAR29394.1 - 7.1e-05 22.8 0.2 0.015 15.4 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 CAR29394.1 - 0.011 15.5 4.9 1.8 8.3 2.3 3.8 2 2 1 3 3 3 0 Rrp7 RRM-like N-terminal domain HTH_Crp_2 PF13545.6 CAR29394.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Ribosomal_L7Ae PF01248.26 CAR29395.1 - 1.9e-23 82.0 0.5 3.1e-23 81.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CAR29395.1 - 0.00082 19.4 0.1 0.0012 18.9 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 FGGY_C PF02782.16 CAR29396.1 - 1.9e-70 236.6 0.1 3.5e-70 235.8 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CAR29396.1 - 7.1e-48 163.3 0.0 9.4e-40 136.7 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.20 CAR29397.1 - 1.2e-69 234.5 5.3 1.5e-69 234.1 5.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein V-SNARE_C PF12352.8 CAR29398.1 - 5e-14 52.3 0.6 5e-14 52.3 0.6 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Not3 PF04065.15 CAR29398.1 - 0.0064 15.9 7.6 0.064 12.7 7.4 2.1 1 1 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Sec34 PF04136.15 CAR29398.1 - 0.039 13.8 9.2 0.93 9.4 2.3 3.0 2 1 1 3 3 3 0 Sec34-like family Syntaxin-6_N PF09177.11 CAR29398.1 - 0.094 13.3 8.9 0.031 14.8 5.5 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Baculo_11_kDa PF06143.11 CAR29398.1 - 0.1 12.2 0.4 0.1 12.2 0.4 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family Prominin PF05478.11 CAR29398.1 - 0.32 8.9 10.8 0.5 8.3 6.0 2.0 1 1 1 2 2 2 0 Prominin SYCE1 PF15233.6 CAR29398.1 - 0.35 10.9 10.9 0.76 9.8 1.3 2.4 1 1 0 2 2 2 0 Synaptonemal complex central element protein 1 FliT PF05400.13 CAR29398.1 - 0.41 11.5 8.9 0.085 13.7 3.8 2.3 2 1 1 3 3 3 0 Flagellar protein FliT FapA PF03961.13 CAR29398.1 - 0.81 8.2 3.0 1 7.9 3.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PMC2NT PF08066.12 CAR29398.1 - 1 10.1 7.8 3.1 8.6 0.4 2.9 2 1 1 3 3 3 0 PMC2NT (NUC016) domain Muted PF14942.6 CAR29398.1 - 2.7 8.3 10.0 2.4 8.5 6.3 2.2 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein Exonuc_VII_L PF02601.15 CAR29398.1 - 4.3 6.8 12.4 6.8 6.2 12.4 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit YabA PF06156.13 CAR29398.1 - 6 7.6 6.8 28 5.4 6.4 2.4 1 1 0 1 1 1 0 Initiation control protein YabA Autophagy_act_C PF03987.15 CAR29399.1 - 2.2e-07 31.4 1.5 9.8e-07 29.3 1.5 2.1 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Fer2_3 PF13085.6 CAR29400.1 - 8e-32 109.5 0.1 1.4e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CAR29400.1 - 7e-09 36.1 7.5 7e-09 36.1 7.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CAR29400.1 - 2e-08 34.6 8.3 2e-08 34.6 8.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CAR29400.1 - 4e-07 30.1 3.7 4e-07 30.1 3.7 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CAR29400.1 - 0.0011 18.9 5.4 0.0064 16.4 1.5 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 CAR29400.1 - 0.0016 19.0 6.0 0.0016 19.0 6.0 2.3 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 CAR29400.1 - 0.0057 16.8 0.4 0.4 10.9 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CAR29400.1 - 0.49 10.6 15.3 0.096 12.9 9.2 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain SHR-BD PF06650.12 CAR29401.1 - 2.3e-93 312.5 5.2 1.9e-92 309.5 1.4 3.6 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 CAR29401.1 - 1.4e-81 273.4 16.3 2e-79 266.4 0.1 5.9 4 1 1 5 5 5 3 Repeating coiled region of VPS13 VPS13 PF16908.5 CAR29401.1 - 2.1e-78 263.4 4.1 1.1e-76 257.8 0.6 3.7 3 0 0 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CAR29401.1 - 1.9e-69 233.0 8.3 9.6e-66 220.9 1.6 2.9 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CAR29401.1 - 5.9e-36 123.1 0.0 3.4e-35 120.7 0.0 2.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 NTP_transf_6 PF06042.11 CAR29401.1 - 0.12 12.2 0.3 1.9 8.4 0.1 2.4 1 1 1 2 2 2 0 Nucleotidyltransferase Ecm29 PF13001.7 CAR29402.1 - 1.3e-149 499.1 7.9 1.7e-147 492.1 2.0 3.0 3 0 0 3 3 3 2 Proteasome stabiliser HEAT PF02985.22 CAR29402.1 - 4.6e-12 45.1 5.0 0.2 12.0 0.0 8.6 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 CAR29402.1 - 3.4e-06 27.5 0.1 0.039 14.6 0.0 4.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CAR29402.1 - 8.1e-05 23.0 0.1 10 6.7 0.1 5.8 5 0 0 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 CAR29402.1 - 0.00096 18.8 0.8 5.5 6.5 0.0 4.5 4 0 0 4 4 4 1 CLASP N terminal ubiquitin PF00240.23 CAR29403.1 - 6.5e-201 650.6 34.7 6.4e-33 112.3 0.6 6.0 6 0 0 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.8 CAR29403.1 - 3.6e-94 308.6 35.5 3.9e-15 55.4 0.7 6.0 6 0 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAR29403.1 - 1.1e-32 112.3 18.9 0.00081 19.8 0.1 8.1 6 6 0 6 6 6 6 Ubiquitin-like domain TBK1_ULD PF18396.1 CAR29403.1 - 2.5e-23 81.8 8.2 0.049 13.6 0.0 6.2 6 0 0 6 6 6 6 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CAR29403.1 - 2.8e-21 75.7 15.8 0.055 13.8 0.1 6.1 6 0 0 6 6 6 6 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAR29403.1 - 3e-20 72.4 6.7 0.23 11.6 0.0 7.0 6 5 0 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CAR29403.1 - 2e-18 66.9 5.0 0.61 10.7 0.0 6.2 1 1 1 6 6 6 6 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 CAR29403.1 - 6.9e-10 38.6 2.9 3.4 6.9 0.0 5.2 5 0 0 5 5 5 5 RNA methyltransferase DUF2870 PF11069.8 CAR29403.1 - 9.9e-09 35.5 0.0 50 4.4 0.0 6.6 6 0 0 6 6 6 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 CAR29403.1 - 4.3e-08 33.1 40.0 28 4.8 0.2 11.8 12 0 0 12 12 12 0 Ubiquitin-like domain DUF3861 PF12977.7 CAR29403.1 - 9.2e-08 32.2 8.0 24 5.2 0.0 6.2 6 0 0 6 6 6 0 Domain of Unknown Function with PDB structure (DUF3861) Big_7 PF17957.1 CAR29403.1 - 2.1e-07 31.6 1.2 91 3.9 0.0 6.1 6 0 0 6 6 6 0 Bacterial Ig domain ACT_5 PF13710.6 CAR29403.1 - 2.9e-07 30.2 10.7 17 5.3 0.0 6.3 6 0 0 6 6 6 0 ACT domain DUF969 PF06149.12 CAR29403.1 - 9.6e-07 28.4 0.1 43 3.4 0.0 5.9 6 0 0 6 6 6 0 Protein of unknown function (DUF969) UDP-g_GGTase PF06427.11 CAR29403.1 - 1.8e-06 28.0 10.6 13 6.0 0.0 5.8 6 0 0 6 6 6 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF493 PF04359.14 CAR29403.1 - 5.9e-05 23.6 0.2 2.3e+02 2.4 0.0 5.8 6 0 0 6 6 6 0 Protein of unknown function (DUF493) ORF11CD3 PF10549.9 CAR29403.1 - 8.4e-05 22.6 0.0 1.5e+02 2.6 0.0 6.0 6 0 0 6 6 6 0 ORF11CD3 domain YcgR_2 PF12945.7 CAR29403.1 - 0.00023 21.2 13.2 48 4.2 0.1 6.2 6 0 0 6 6 6 0 Flagellar protein YcgR ACT_4 PF13291.6 CAR29403.1 - 0.0011 19.5 4.4 2.4e+02 2.4 0.0 6.0 6 0 0 6 6 6 0 ACT domain Baculo_p48 PF04878.13 CAR29403.1 - 0.0061 15.6 0.0 1.1e+02 1.5 0.0 4.6 5 0 0 5 5 5 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 CAR29403.1 - 0.23 11.6 12.6 1.7e+02 2.4 0.1 5.9 6 0 0 6 6 6 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 CAR29403.1 - 0.34 11.1 44.7 9.9 6.5 1.4 6.3 6 0 0 6 6 6 0 Tash protein PEST motif HAMP_N3 PF18575.1 CAR29403.1 - 0.35 10.5 5.4 3.2e+02 1.0 0.0 5.4 6 0 0 6 6 6 0 HAMP N-terminal domain 3 ENTH PF01417.20 CAR29404.1 - 2.5e-32 111.6 0.3 3.5e-32 111.1 0.3 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CAR29404.1 - 0.0015 17.6 0.1 0.0022 17.1 0.1 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.19 CAR29404.1 - 0.075 12.9 0.3 0.18 11.7 0.2 1.7 1 1 0 1 1 1 0 VHS domain HEPN_Apea PF18739.1 CAR29404.1 - 0.18 12.3 1.2 0.42 11.1 1.2 1.7 1 1 0 1 1 1 0 Apea-like HEPN Prp19 PF08606.11 CAR29405.1 - 4e-28 97.2 2.6 7.4e-28 96.3 2.6 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.8 CAR29405.1 - 0.03 14.1 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 CAR29405.1 - 0.15 12.3 0.1 0.57 10.4 0.0 2.0 2 0 0 2 2 2 0 U-box domain RabGAP-TBC PF00566.18 CAR29406.1 - 7e-11 42.2 2.6 8.5e-05 22.3 0.0 2.9 4 0 0 4 4 4 2 Rab-GTPase-TBC domain TMEM132D_C PF15706.5 CAR29407.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Binary_toxB PF03495.14 CAR29407.1 - 0.1 12.8 0.5 0.72 10.1 0.5 2.5 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain zf-C2H2 PF00096.26 CAR29408.1 - 3.4e-08 33.5 19.2 0.00012 22.4 2.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR29408.1 - 0.0073 17.1 1.0 0.0073 17.1 1.0 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR29408.1 - 0.019 15.4 2.9 0.019 15.4 2.9 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2HE PF16278.5 CAR29408.1 - 0.035 14.6 8.1 0.18 12.3 8.1 2.3 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger FOXP-CC PF16159.5 CAR29408.1 - 0.037 14.6 11.3 0.27 11.9 1.8 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-met PF12874.7 CAR29408.1 - 0.087 13.2 2.4 0.28 11.7 0.1 2.9 2 1 1 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CAR29408.1 - 0.11 12.5 0.9 1.9 8.5 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-LYAR PF08790.11 CAR29408.1 - 0.12 12.2 1.6 4.1 7.4 0.2 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_8 PF15909.5 CAR29408.1 - 0.14 12.5 9.6 1.1 9.6 3.2 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CAR29408.1 - 0.22 11.9 0.2 0.22 11.9 0.2 3.0 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 CAR29408.1 - 3 8.0 4.8 6 7.1 0.2 3.2 3 0 0 3 3 3 0 Zic proteins zinc finger domain CLP1_P PF16575.5 CAR29409.1 - 2.9e-32 112.0 0.0 5.4e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 CAR29409.1 - 0.00093 19.2 1.2 0.0019 18.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CAR29409.1 - 0.071 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 CAR29409.1 - 0.071 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CAR29409.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arf PF00025.21 CAR29409.1 - 0.15 11.5 0.1 0.28 10.6 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.29 CAR29410.1 - 1.2e-92 307.2 0.0 8.4e-47 158.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR29410.1 - 1.1e-22 79.5 0.7 4.5e-10 39.2 0.1 3.1 2 1 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CAR29410.1 - 1.6e-14 54.0 0.0 5.8e-07 29.4 0.0 3.1 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAR29410.1 - 2.7e-13 50.7 0.4 6.8e-05 23.3 0.0 4.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CAR29410.1 - 6.4e-10 39.2 0.1 0.00051 20.1 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CAR29410.1 - 1.4e-09 38.3 0.2 0.036 14.4 0.0 4.8 2 2 3 5 5 5 2 AAA domain Vps4_C PF09336.10 CAR29410.1 - 1.9e-09 37.4 0.7 3.7e-05 23.6 0.0 3.2 3 0 0 3 3 2 2 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 CAR29410.1 - 2.4e-09 37.5 0.0 0.00041 20.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CAR29410.1 - 3e-09 37.2 0.0 0.00093 19.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CAR29410.1 - 5.6e-09 36.6 0.5 0.00043 20.8 0.0 3.8 4 1 1 5 5 3 2 AAA domain TIP49 PF06068.13 CAR29410.1 - 1.3e-08 34.5 0.0 0.00049 19.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 CAR29410.1 - 6.1e-08 33.0 0.0 0.0069 16.8 0.0 3.2 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 CAR29410.1 - 3e-07 31.0 0.0 0.015 15.8 0.0 3.0 2 0 0 2 2 2 2 ABC transporter AAA_14 PF13173.6 CAR29410.1 - 6.3e-07 29.5 0.0 0.044 13.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 CAR29410.1 - 1.4e-06 27.8 0.0 0.043 13.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.21 CAR29410.1 - 3.2e-06 26.7 0.2 0.049 13.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CAR29410.1 - 3.4e-06 26.9 0.1 0.043 13.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 CAR29410.1 - 3.9e-06 26.9 0.0 0.068 13.1 0.0 3.2 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_28 PF13521.6 CAR29410.1 - 1e-05 25.9 0.0 0.12 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 CAR29410.1 - 1.7e-05 24.7 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Hydin_ADK PF17213.3 CAR29410.1 - 7.5e-05 23.1 1.5 0.27 11.5 0.0 4.0 4 0 0 4 4 4 1 Hydin Adenylate kinase-like domain TsaE PF02367.17 CAR29410.1 - 7.6e-05 22.7 0.0 0.64 10.0 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 CAR29410.1 - 8e-05 22.1 0.0 2.1 7.7 0.0 3.7 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit NACHT PF05729.12 CAR29410.1 - 8.1e-05 22.6 0.0 0.52 10.2 0.0 3.0 3 0 0 3 3 2 2 NACHT domain AAA_7 PF12775.7 CAR29410.1 - 9e-05 22.1 0.0 0.61 9.6 0.0 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 CAR29410.1 - 0.00011 22.4 0.0 0.0051 17.0 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family DUF815 PF05673.13 CAR29410.1 - 0.00022 20.5 0.0 0.14 11.3 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 CAR29410.1 - 0.00026 21.4 2.9 0.15 12.5 0.0 3.5 4 0 0 4 4 2 1 AAA domain Sigma54_activat PF00158.26 CAR29410.1 - 0.00029 20.6 0.0 0.26 11.0 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_11 PF13086.6 CAR29410.1 - 0.0003 20.7 3.1 0.51 10.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 CAR29410.1 - 0.00033 20.3 0.2 1.9 8.0 0.0 3.5 3 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.18 CAR29410.1 - 0.00033 20.5 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase SKI PF01202.22 CAR29410.1 - 0.00046 20.3 0.0 0.68 10.0 0.0 3.0 2 0 0 2 2 2 1 Shikimate kinase CPT PF07931.12 CAR29410.1 - 0.00066 19.6 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 CAR29410.1 - 0.00069 18.9 0.0 1 8.5 0.0 3.2 4 0 0 4 4 4 1 NB-ARC domain Sigma54_activ_2 PF14532.6 CAR29410.1 - 0.00071 19.7 0.0 2.9 8.0 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_24 PF13479.6 CAR29410.1 - 0.00072 19.3 0.0 0.86 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CAR29410.1 - 0.0019 18.1 0.0 2.4 8.0 0.0 3.3 3 1 1 4 4 3 1 ATPase domain predominantly from Archaea ATPase PF06745.13 CAR29410.1 - 0.0021 17.5 0.1 1.6 8.0 0.0 3.2 3 0 0 3 3 3 1 KaiC Cytidylate_kin PF02224.18 CAR29410.1 - 0.0024 17.7 0.2 0.42 10.3 0.0 3.3 3 0 0 3 3 3 1 Cytidylate kinase Parvo_NS1 PF01057.17 CAR29410.1 - 0.0026 16.9 0.0 1.9 7.5 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PduV-EutP PF10662.9 CAR29410.1 - 0.017 14.8 0.0 7.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 CAR29410.1 - 0.02 14.4 0.1 2.8 7.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AFG1_ATPase PF03969.16 CAR29410.1 - 0.025 13.5 0.0 9.7 5.0 0.0 2.9 3 0 0 3 3 3 0 AFG1-like ATPase NTPase_1 PF03266.15 CAR29410.1 - 0.029 14.3 0.2 12 5.7 0.0 3.0 3 0 0 3 3 2 0 NTPase AAA_19 PF13245.6 CAR29410.1 - 0.029 14.7 0.1 9.3 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 CAR29410.1 - 0.055 13.0 0.1 2.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAR29410.1 - 0.056 13.4 0.0 0.84 9.5 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase IPT PF01745.16 CAR29410.1 - 0.064 12.6 0.5 35 3.7 0.0 3.1 3 0 0 3 3 3 0 Isopentenyl transferase TniB PF05621.11 CAR29410.1 - 0.078 12.4 0.0 18 4.6 0.0 2.9 3 0 0 3 3 2 0 Bacterial TniB protein Bac_DnaA PF00308.18 CAR29410.1 - 0.089 12.6 0.1 4.9 6.9 0.0 3.4 4 0 0 4 4 4 0 Bacterial dnaA protein MMR_HSR1 PF01926.23 CAR29410.1 - 0.1 12.7 0.2 3.7 7.7 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 CAR29410.1 - 0.17 11.6 0.1 20 4.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CAR29410.1 - 0.43 11.0 5.8 1.2 9.6 0.0 3.5 3 0 0 3 3 2 0 AAA domain DUF2456 PF10445.9 CAR29411.1 - 7e-36 122.2 3.1 1.4e-35 121.3 3.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) MatE PF01554.18 CAR29411.1 - 0.026 14.2 0.3 0.077 12.6 0.3 1.8 1 1 0 1 1 1 0 MatE Spc7 PF08317.11 CAR29412.1 - 6.1e-52 176.4 14.9 6.1e-52 176.4 14.9 2.2 2 1 0 2 2 2 1 Spc7 kinetochore protein DUF2564 PF10819.8 CAR29412.1 - 0.9 10.0 6.4 4.2 7.8 1.6 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2564) Nucleoporin2 PF04096.14 CAR29413.1 - 2.4e-48 164.0 0.0 4.3e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.8 CAR29413.1 - 3.8e-28 98.5 1.0 4.2e-27 95.0 1.0 2.3 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin_FG PF13634.6 CAR29413.1 - 1.2e-11 45.3 102.4 3e-06 28.0 31.5 4.3 2 2 3 5 5 5 4 Nucleoporin FG repeat region Shugoshin_N PF07558.11 CAR29413.1 - 0.033 14.0 0.2 0.094 12.6 0.2 1.8 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region ParA PF10609.9 CAR29414.1 - 2.5e-94 315.4 0.0 2.9e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CAR29414.1 - 7.4e-10 39.0 0.0 2.5e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CAR29414.1 - 7e-06 26.1 0.4 9.5e-05 22.4 0.4 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CAR29414.1 - 6.3e-05 22.4 0.0 0.0001 21.7 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CAR29414.1 - 0.0013 18.0 2.5 0.0085 15.3 0.6 2.3 1 1 0 2 2 2 1 Anion-transporting ATPase RsgA_GTPase PF03193.16 CAR29414.1 - 0.0056 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CAR29414.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 CAR29414.1 - 0.028 13.9 0.0 1.9 7.9 0.0 2.6 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 CAR29414.1 - 0.028 14.2 0.0 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 CAR29414.1 - 0.031 13.8 0.1 0.14 11.6 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ AAA_15 PF13175.6 CAR29414.1 - 0.038 13.7 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain TF_Zn_Ribbon PF08271.12 CAR29414.1 - 0.055 13.0 0.4 0.15 11.6 0.4 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding Rad17 PF03215.15 CAR29414.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 CAR29414.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain zf_Rg PF17915.1 CAR29414.1 - 4.1 6.9 6.4 3.6 7.0 0.2 2.4 2 0 0 2 2 2 0 Reverse gyrase zinc finger OmpH PF03938.14 CAR29415.1 - 0.0072 16.7 1.1 0.013 15.8 1.1 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Atg14 PF10186.9 CAR29415.1 - 0.011 14.9 2.6 0.016 14.3 2.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SPAM PF02090.15 CAR29415.1 - 0.012 15.5 5.3 0.027 14.3 5.3 1.6 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein RRM_1 PF00076.22 CAR29416.1 - 7.8e-26 89.7 0.6 6.6e-07 29.1 0.0 4.9 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR29416.1 - 6.3e-12 45.2 0.0 0.013 15.3 0.0 4.5 4 0 0 4 4 4 4 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CAR29416.1 - 0.0032 17.4 0.0 4.4 7.4 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif AMPK1_CBM PF16561.5 CAR29417.1 - 0.0005 20.2 1.1 0.00059 20.0 0.2 1.6 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase MF_alpha PF04648.12 CAR29418.1 - 1.8e-20 72.3 25.1 0.49 10.8 0.1 8.5 8 1 0 8 8 8 8 Yeast mating factor alpha hormone CLP1_P PF16575.5 CAR29418.1 - 7.8e-08 32.3 0.0 41 3.9 0.0 7.5 1 1 7 8 8 8 0 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF4601 PF15373.6 CAR29418.1 - 0.00029 20.0 0.2 2.5 7.0 0.0 2.9 1 1 1 2 2 2 2 Domain of unknown function (DUF4601) TFIIIC_sub6 PF10419.9 CAR29418.1 - 0.00044 20.1 0.0 1.2 9.1 0.0 4.1 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain ADH_N_2 PF16884.5 CAR29418.1 - 0.0083 16.0 0.0 50 3.9 0.0 3.8 1 1 3 4 4 4 0 N-terminal domain of oxidoreductase Apidaecin PF00807.17 CAR29418.1 - 0.015 15.4 16.2 38 4.5 0.1 6.2 6 0 0 6 6 6 0 Apidaecin NAD_kinase PF01513.21 CAR29419.1 - 7e-55 186.3 0.0 9.6e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 CAR29419.1 - 0.0066 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain UQ_con PF00179.26 CAR29420.1 - 2.4e-20 72.6 0.0 2.5e-20 72.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAR29420.1 - 0.0018 18.6 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain MAD PF05557.13 CAR29421.1 - 1.4e-26 93.1 80.2 2.3e-26 92.4 80.2 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein UreF PF01730.16 CAR29421.1 - 0.12 13.0 0.8 3.3 8.3 0.0 2.5 2 0 0 2 2 2 0 UreF SNase PF00565.17 CAR29422.1 - 1.8e-26 92.7 0.0 2.5e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MBOAT PF03062.19 CAR29423.1 - 2.6e-65 221.1 21.1 3.7e-65 220.6 21.1 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.25 CAR29424.1 - 6.6e-24 84.7 0.1 1.4e-23 83.7 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29424.1 - 1.6e-13 50.5 0.0 2.9e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ParcG PF10274.9 CAR29424.1 - 0.035 14.2 0.4 0.11 12.6 0.4 1.9 1 0 0 1 1 1 0 Parkin co-regulated protein COA2 PF17051.5 CAR29425.1 - 1.3e-15 57.3 0.1 1.3e-15 57.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 RRM_1 PF00076.22 CAR29426.1 - 6.4e-10 38.7 0.5 1.4e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR29426.1 - 9.5e-05 22.0 0.0 0.00032 20.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIF_alpha PF05793.12 CAR29426.1 - 6.9 5.1 49.0 12 4.3 49.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MINDY_DUB PF04424.13 CAR29427.1 - 3.3e-29 101.3 0.0 6.4e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase FHA PF00498.26 CAR29428.1 - 2.7e-06 27.6 0.1 2.1e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 FHA domain NUFIP1 PF10453.9 CAR29430.1 - 5e-19 67.9 5.5 1.7e-18 66.2 5.5 1.9 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF413 PF04219.12 CAR29430.1 - 0.087 12.9 0.9 0.15 12.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF RabGAP-TBC PF00566.18 CAR29430.1 - 0.19 11.3 4.1 0.28 10.8 4.1 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain DUF1828 PF08861.10 CAR29430.1 - 0.41 10.9 2.3 0.57 10.5 1.1 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF1828 ANAPC_CDC26 PF10471.9 CAR29430.1 - 3.4 8.6 6.4 0.73 10.7 1.5 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 MPC PF03650.13 CAR29431.1 - 1.3e-40 137.9 0.1 1.6e-40 137.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Rad9 PF04139.13 CAR29432.1 - 6.1e-09 35.7 0.8 4.2e-07 29.7 0.8 2.3 1 1 0 1 1 1 1 Rad9 Adaptin_N PF01602.20 CAR29433.1 - 8.1e-116 387.6 8.5 1.1e-115 387.2 8.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CAR29433.1 - 1.1e-11 45.1 4.1 4.6e-11 43.0 0.1 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CAR29433.1 - 5.7e-06 26.1 1.5 16 6.1 0.0 6.0 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 CAR29433.1 - 0.00031 21.1 0.0 0.11 12.8 0.0 3.5 2 1 2 4 4 4 1 HEAT repeats Cnd3 PF12719.7 CAR29433.1 - 0.0033 16.6 0.2 0.037 13.2 0.0 2.7 2 2 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 CAR29433.1 - 0.0078 16.4 0.6 1.1 9.5 0.0 3.4 2 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 CAR29433.1 - 0.058 14.0 4.1 0.13 12.9 0.2 3.5 3 2 1 4 4 4 0 Vacuolar 14 Fab1-binding region KxDL PF10241.9 CAR29434.1 - 4.1e-24 84.7 0.9 6.4e-24 84.0 0.9 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein DCB PF16213.5 CAR29434.1 - 0.068 12.8 0.9 0.097 12.3 0.4 1.5 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 TLD PF07534.16 CAR29435.1 - 6.5e-31 107.4 0.2 2.2e-30 105.7 0.2 1.8 1 1 0 1 1 1 1 TLD DEAD PF00270.29 CAR29436.1 - 8.5e-54 182.0 0.0 5.4e-53 179.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR29436.1 - 1.9e-36 124.8 0.4 1.2e-30 106.1 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CAR29436.1 - 2.5e-10 40.6 0.0 2.5e-10 40.6 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CAR29436.1 - 0.0071 15.7 0.0 0.0071 15.7 0.0 3.2 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 CAR29436.1 - 0.017 14.0 0.1 0.017 14.0 0.1 3.6 3 1 1 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CAR29436.1 - 0.02 15.2 1.8 0.14 12.5 1.8 2.4 1 1 0 1 1 1 0 AAA domain NCKAP5 PF15246.6 CAR29436.1 - 0.15 11.7 26.5 0.27 10.8 26.5 1.4 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein DDHD PF02862.17 CAR29436.1 - 0.21 11.7 5.1 0.43 10.7 5.1 1.6 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 CAR29436.1 - 6.2 5.5 18.5 12 4.6 18.5 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AA_permease_2 PF13520.6 CAR29437.1 - 6e-50 170.3 51.0 7.2e-50 170.1 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CAR29437.1 - 3.7e-23 81.9 40.5 4.9e-23 81.5 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L30_N PF08079.12 CAR29438.1 - 2.4e-21 75.8 13.0 2.4e-21 75.8 13.0 1.9 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CAR29438.1 - 4.7e-18 64.8 3.6 1.1e-17 63.6 2.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF1771 PF08590.10 CAR29439.1 - 3.1e-16 59.5 12.5 5.4e-16 58.7 12.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 CAR29439.1 - 1.2e-11 44.8 0.5 2.9e-10 40.3 0.0 2.6 3 0 0 3 3 3 1 Smr domain CYSTM PF12734.7 CAR29439.1 - 0.2 12.0 20.3 0.67 10.3 20.3 1.9 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance MRP-L46 PF11788.8 CAR29439.1 - 0.22 12.3 5.3 1 10.1 5.2 2.1 1 1 0 1 1 1 0 39S mitochondrial ribosomal protein L46 NYAP_C PF15452.6 CAR29439.1 - 1 9.2 5.3 0.48 10.2 1.0 2.0 2 0 0 2 2 2 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter MPS2 PF17060.5 CAR29440.1 - 8.6e-131 436.6 6.0 9.8e-131 436.4 6.0 1.0 1 0 0 1 1 1 1 Monopolar spindle protein 2 DUF641 PF04859.12 CAR29440.1 - 0.00071 19.9 5.4 0.00071 19.9 5.4 2.0 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) SlyX PF04102.12 CAR29440.1 - 0.0017 18.9 3.1 0.14 12.8 0.1 2.4 2 0 0 2 2 2 2 SlyX Spatacsin_C PF14649.6 CAR29440.1 - 0.048 12.8 0.4 0.073 12.2 0.4 1.2 1 0 0 1 1 1 0 Spatacsin C-terminus SAB PF04382.13 CAR29440.1 - 0.06 13.4 1.5 0.14 12.2 1.5 1.7 1 0 0 1 1 1 0 SAB domain Tropomyosin_1 PF12718.7 CAR29440.1 - 0.069 13.3 8.1 0.15 12.2 5.6 2.0 1 1 1 2 2 2 0 Tropomyosin like FAM76 PF16046.5 CAR29440.1 - 0.21 10.9 9.2 0.71 9.2 6.4 2.0 1 1 1 2 2 2 0 FAM76 protein Exonuc_VII_L PF02601.15 CAR29440.1 - 0.22 11.1 6.1 0.29 10.6 6.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 CAR29440.1 - 0.51 10.4 2.5 0.82 9.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sec2p PF06428.11 CAR29440.1 - 3.6 7.6 9.5 3.3 7.7 1.5 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p HSF_DNA-bind PF00447.17 CAR29441.1 - 2.6e-31 108.1 3.6 6.5e-31 106.8 3.6 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding MetOD2 PF18548.1 CAR29441.1 - 0.07 13.2 1.5 0.11 12.6 0.3 2.0 2 0 0 2 2 2 0 Metanogen output domain 2 AFT PF08731.11 CAR29443.1 - 3.1e-45 153.2 1.7 3.1e-45 153.2 1.7 2.6 2 1 0 2 2 2 1 Transcription factor AFT RNA_POL_M_15KD PF02150.16 CAR29444.1 - 4e-16 58.6 4.9 4e-16 58.6 4.9 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CAR29444.1 - 2.6e-14 52.8 15.3 4.4e-14 52.0 2.1 3.1 2 1 1 3 3 3 1 Transcription factor S-II (TFIIS) zf-UBP PF02148.19 CAR29444.1 - 0.052 13.9 4.4 0.69 10.3 0.4 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Zn_Tnp_IS1595 PF12760.7 CAR29444.1 - 0.13 12.3 11.1 0.74 9.8 3.2 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF2387 PF09526.10 CAR29444.1 - 0.16 12.1 5.4 1.1 9.4 0.2 2.5 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) DZR PF12773.7 CAR29444.1 - 0.23 11.5 7.4 1.9 8.6 0.6 2.5 2 1 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.20 CAR29444.1 - 0.35 10.9 5.0 33 4.6 0.0 3.4 4 0 0 4 4 4 0 Rubredoxin Lar_restr_allev PF14354.6 CAR29444.1 - 1.4 9.4 6.7 0.44 11.0 0.3 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar RPA_interact_C PF14768.6 CAR29444.1 - 2.5 8.7 8.8 2.7 8.6 0.9 2.5 2 1 0 2 2 2 0 Replication protein A interacting C-terminal Ribosomal_L12 PF00542.19 CAR29445.1 - 1.8e-20 73.1 7.0 1.8e-20 73.1 7.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CAR29445.1 - 1.5e-13 50.2 2.1 1.5e-13 50.2 2.1 2.4 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain BID PF06393.11 CAR29445.1 - 0.099 12.2 0.2 0.16 11.5 0.2 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) Ribosomal_60s PF00428.19 CAR29445.1 - 0.47 11.1 16.4 0.046 14.3 9.1 2.4 1 1 2 3 3 3 0 60s Acidic ribosomal protein Pkinase PF00069.25 CAR29446.1 - 4e-72 242.8 0.0 4.8e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29446.1 - 1.3e-38 132.7 0.0 1.8e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR29446.1 - 0.00012 21.5 0.2 0.00032 20.1 0.2 1.9 1 1 1 2 2 2 1 Kinase-like WaaY PF06176.11 CAR29446.1 - 0.0032 17.1 0.4 0.0053 16.4 0.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Seadorna_VP7 PF07387.11 CAR29446.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.25 CAR29447.1 - 3.4e-24 85.6 0.0 5.5e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29447.1 - 3.2e-16 59.4 0.0 5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR29447.1 - 1.6e-08 33.7 1.5 2.6e-08 33.1 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CAR29447.1 - 0.019 14.9 2.1 0.083 12.8 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family ASD2 PF08687.11 CAR29447.1 - 7.7 6.0 7.3 6.5 6.2 5.8 1.6 1 1 0 1 1 1 0 Apx/Shroom domain ASD2 CBFD_NFYB_HMF PF00808.23 CAR29448.1 - 3.6e-25 88.0 0.0 5.3e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CAR29448.1 - 3e-05 24.4 0.1 5.2e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CAR29448.1 - 0.0075 16.4 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 CAR29448.1 - 0.085 13.4 0.1 0.42 11.2 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Lon_C PF05362.13 CAR29449.1 - 3.8e-66 222.5 0.0 7.1e-66 221.6 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CAR29449.1 - 2.4e-39 135.4 0.8 6.9e-39 133.9 0.8 1.9 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CAR29449.1 - 2.7e-23 82.9 0.0 7.3e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAR29449.1 - 3.2e-06 27.2 0.0 9.9e-06 25.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CAR29449.1 - 3.7e-06 27.2 0.0 2e-05 24.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 CAR29449.1 - 6.8e-06 25.9 0.0 2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 CAR29449.1 - 2.9e-05 23.1 0.0 0.00036 19.5 0.0 2.2 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.6 CAR29449.1 - 7e-05 23.1 0.5 0.00093 19.5 0.1 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CAR29449.1 - 0.0016 18.2 0.0 0.0079 15.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CAR29449.1 - 0.0026 18.2 0.9 0.018 15.5 0.1 2.6 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 CAR29449.1 - 0.0035 17.1 0.0 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CAR29449.1 - 0.0062 16.6 0.1 0.028 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CAR29449.1 - 0.013 15.8 0.0 0.27 11.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase SKI PF01202.22 CAR29449.1 - 0.015 15.4 0.2 0.085 13.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase RsgA_GTPase PF03193.16 CAR29449.1 - 0.044 13.7 0.0 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 RsgA GTPase AAA_18 PF13238.6 CAR29449.1 - 0.052 14.1 0.0 0.052 14.1 0.0 3.2 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 CAR29449.1 - 0.08 12.9 0.5 2.7 7.9 0.1 3.1 2 1 1 3 3 3 0 NTPase AAA_7 PF12775.7 CAR29449.1 - 0.12 11.9 0.8 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Aldedh PF00171.22 CAR29450.1 - 1.3e-162 541.5 0.0 1.5e-162 541.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-UBR PF02207.20 CAR29451.1 - 1.5e-09 37.9 11.4 1.5e-09 37.9 11.4 2.7 2 1 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.23 CAR29452.1 - 4e-102 340.1 0.0 6.6e-102 339.3 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR29452.1 - 1.8e-36 124.8 0.0 3.3e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 CAR29452.1 - 1.9e-26 93.2 34.4 1.9e-26 93.2 34.4 4.3 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 CAR29452.1 - 3.5e-25 88.2 0.2 8.7e-25 87.0 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CAR29452.1 - 3.5e-12 46.8 0.0 9.6e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CAR29452.1 - 1.7e-08 34.1 0.0 3.1e-06 26.7 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CAR29452.1 - 8.2e-07 29.1 0.0 2.1e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CAR29452.1 - 0.00016 21.6 0.0 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CAR29452.1 - 0.017 14.9 0.1 0.089 12.5 0.1 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain SelR PF01641.18 CAR29452.1 - 0.057 13.5 0.0 0.98 9.5 0.1 2.3 2 0 0 2 2 2 0 SelR domain Methyltr_RsmB-F PF01189.17 CAR29453.1 - 2.4e-43 148.1 0.0 8.9e-43 146.3 0.0 1.9 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CAR29453.1 - 0.0014 18.8 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DGF-1_5 PF11038.8 CAR29453.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Nitr_red_alph_N PF14710.6 CAR29453.1 - 0.18 12.3 0.7 0.47 10.9 0.7 1.7 1 0 0 1 1 1 0 Respiratory nitrate reductase alpha N-terminal RNA_pol_Rpc4 PF05132.14 CAR29453.1 - 5.9 7.3 7.5 7 7.1 0.2 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 UAF_Rrn10 PF05234.11 CAR29454.1 - 3.2e-46 156.5 0.0 3.8e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 UAF complex subunit Rrn10 zf-C2H2_10 PF16588.5 CAR29455.1 - 1.8e-14 53.1 4.2 3.1e-14 52.3 4.2 1.4 1 0 0 1 1 1 1 C2H2 zinc-finger zf-CCHC PF00098.23 CAR29455.1 - 0.011 15.7 2.5 0.017 15.1 2.5 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 CAR29455.1 - 0.11 12.2 1.0 0.21 11.4 1.0 1.4 1 0 0 1 1 1 0 Zinc knuckle zinc_ribbon_12 PF11331.8 CAR29455.1 - 0.13 12.1 0.1 0.32 10.8 0.1 1.6 1 0 0 1 1 1 0 Probable zinc-ribbon domain LSM PF01423.22 CAR29456.1 - 1.6e-18 66.2 0.2 1.9e-18 65.9 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CAR29456.1 - 0.074 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Hfq protein GDI PF00996.18 CAR29457.1 - 4.7e-226 750.3 0.2 5.4e-226 750.1 0.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CAR29457.1 - 0.003 17.7 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ABC_tran PF00005.27 CAR29458.1 - 2e-22 80.2 0.0 1.8e-12 47.9 0.0 3.1 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAR29458.1 - 6.9e-08 32.6 0.0 0.00049 20.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CAR29458.1 - 0.0054 16.9 0.0 0.45 10.8 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CAR29458.1 - 0.0084 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Ploopntkinase1 PF18748.1 CAR29458.1 - 0.027 14.0 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Aminotran_1_2 PF00155.21 CAR29459.1 - 5.9e-72 242.8 0.0 7e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CAR29459.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V OKR_DC_1 PF01276.20 CAR29459.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Cofilin_ADF PF00241.20 CAR29460.1 - 2e-18 66.3 0.3 2.4e-18 66.1 0.3 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Securin PF04856.13 CAR29460.1 - 0.075 13.0 0.7 0.1 12.6 0.7 1.2 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor Ribosomal_S13_N PF08069.12 CAR29461.1 - 1.6e-29 101.8 0.2 2.9e-29 100.9 0.2 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CAR29461.1 - 1.6e-14 53.8 0.7 2.6e-14 53.2 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 Gly_transf_sug PF04488.15 CAR29462.1 - 1.9e-14 54.1 0.1 7.1e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CAR29462.1 - 0.00032 20.2 0.1 0.00083 18.8 0.0 1.8 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Isochorismatase PF00857.20 CAR29463.1 - 3.4e-25 89.2 0.0 4.8e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family NUC153 PF08159.12 CAR29466.1 - 3.4e-09 36.4 4.9 6.4e-09 35.5 4.9 1.5 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 CAR29466.1 - 0.032 14.5 0.0 0.23 11.8 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain V-SNARE_C PF12352.8 CAR29467.1 - 0.035 14.4 1.3 0.18 12.1 0.3 2.7 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Ecl1 PF12855.7 CAR29468.1 - 1.2e-08 36.3 0.1 1.5e-08 36.0 0.1 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 CAR29468.1 - 0.082 13.0 0.2 0.19 11.9 0.2 1.6 1 0 0 1 1 1 0 MYND finger zf-H2C2_2 PF13465.6 CAR29469.1 - 1.3e-10 41.2 14.8 1.2e-06 28.7 3.8 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CAR29469.1 - 3.2e-08 33.6 19.1 8.9e-05 22.7 2.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR29469.1 - 0.00024 21.7 15.4 0.044 14.6 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CAR29469.1 - 0.022 14.7 9.8 1.4 9.0 3.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CAR29469.1 - 1.1 9.2 5.1 13 5.8 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TBPIP PF07106.13 CAR29470.1 - 4.3e-24 84.2 0.4 2.4e-23 81.8 0.0 2.2 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain SoDot-IcmSS PF16848.5 CAR29470.1 - 0.028 14.4 1.7 0.051 13.6 1.2 1.7 1 1 0 1 1 1 0 Substrate of the Dot/Icm secretion system, putative S-AdoMet_synt_M PF02772.16 CAR29470.1 - 0.031 14.5 0.5 0.29 11.4 0.1 2.1 1 1 1 2 2 2 0 S-adenosylmethionine synthetase, central domain RE_NgoFVII PF09565.10 CAR29470.1 - 0.033 13.5 0.1 0.038 13.3 0.1 1.1 1 0 0 1 1 1 0 NgoFVII restriction endonuclease DUF4140 PF13600.6 CAR29470.1 - 0.08 13.4 0.7 0.26 11.7 0.1 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FTO_CTD PF12934.7 CAR29470.1 - 0.11 12.2 1.9 0.41 10.4 0.3 2.1 1 1 1 2 2 2 0 FTO C-terminal domain ZapB PF06005.12 CAR29470.1 - 0.16 12.5 5.8 0.45 11.0 5.8 1.8 1 0 0 1 1 1 0 Cell division protein ZapB E2F_CC-MB PF16421.5 CAR29470.1 - 0.31 11.4 2.4 0.77 10.2 0.9 2.2 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain DALR_2 PF09190.11 CAR29470.1 - 2.4 8.7 5.4 17 6.0 0.9 2.9 2 1 1 3 3 3 0 DALR domain Uricase PF01014.18 CAR29471.1 - 8.1e-65 217.0 0.7 5.2e-33 114.1 0.4 2.0 2 0 0 2 2 2 2 Uricase DUF1279 PF06916.13 CAR29472.1 - 7.7e-26 90.5 0.0 1.2e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L24e PF01246.20 CAR29473.1 - 1.3e-28 99.0 0.1 1.3e-28 99.0 0.1 2.0 2 1 0 2 2 2 1 Ribosomal protein L24e Ribosomal_L7Ae PF01248.26 CAR29474.1 - 1.2e-23 82.6 0.1 1.3e-23 82.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Staufen_C PF16482.5 CAR29474.1 - 0.082 13.1 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Staufen C-terminal domain DUF2838 PF10998.8 CAR29475.1 - 2.6e-41 140.3 14.0 2.6e-41 140.3 14.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2838) PPR_2 PF13041.6 CAR29476.1 - 2.4e-17 62.8 2.9 7.2e-11 42.1 0.0 4.0 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 CAR29476.1 - 5.5e-09 35.7 0.0 0.00031 20.8 0.0 3.6 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 CAR29476.1 - 6.4e-09 35.8 0.1 9e-05 22.5 0.0 3.1 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 CAR29476.1 - 3.5e-06 26.6 0.0 0.018 14.7 0.0 2.8 2 0 0 2 2 2 2 PPR repeat PPR_long PF17177.4 CAR29476.1 - 2.5e-05 23.7 3.4 0.00013 21.4 0.1 2.5 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 CAR29476.1 - 0.079 13.0 1.2 0.22 11.6 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PPP5 PF08321.12 CAR29476.1 - 1.3 9.4 5.3 1.2 9.5 0.8 3.1 2 1 1 3 3 3 0 PPP5 TPR repeat region Cgr1 PF03879.14 CAR29477.1 - 7.5e-31 106.7 31.4 8.8e-31 106.5 31.4 1.1 1 0 0 1 1 1 1 Cgr1 family DUF2048 PF09752.9 CAR29477.1 - 1.5 7.8 6.1 1.9 7.5 6.1 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 MIOX PF05153.15 CAR29478.1 - 3.5e-117 390.4 7.7 4.3e-117 390.1 7.7 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 CAR29478.1 - 7.4e-05 23.0 1.0 0.53 10.5 0.0 3.2 3 0 0 3 3 3 2 HD domain Clc-like PF07062.12 CAR29478.1 - 0.79 9.2 3.1 1 8.8 0.1 2.2 1 1 1 2 2 2 0 Clc-like Glyco_hydro_17 PF00332.18 CAR29479.1 - 8.9e-05 22.2 0.9 0.0047 16.6 0.3 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 SOG2 PF10428.9 CAR29479.1 - 2.8 7.0 37.7 4.8 6.3 37.7 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_hydro_63 PF03200.16 CAR29480.1 - 1.9e-169 564.6 0.5 1.3e-168 561.8 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CAR29480.1 - 9.5e-65 218.9 0.0 1.9e-64 217.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain FlaE PF07559.14 CAR29480.1 - 0.032 14.8 0.2 0.12 13.0 0.1 1.9 2 1 0 2 2 2 0 Flagellar basal body protein FlaE Rrn6 PF10214.9 CAR29481.1 - 9.8e-156 520.6 14.0 9.8e-156 520.6 14.0 1.5 2 0 0 2 2 2 1 RNA polymerase I-specific transcription-initiation factor Trp_syntA PF00290.20 CAR29482.1 - 3.8e-98 327.5 0.4 6.2e-98 326.8 0.4 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 CAR29482.1 - 1e-47 163.0 1.2 1e-47 163.0 1.2 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Cor1 PF04803.12 CAR29482.1 - 0.022 15.0 0.2 0.054 13.7 0.2 1.6 1 0 0 1 1 1 0 Cor1/Xlr/Xmr conserved region BtpA PF03437.15 CAR29482.1 - 0.1 12.0 0.4 1.1 8.6 0.1 2.3 2 0 0 2 2 2 0 BtpA family Med3 PF11593.8 CAR29483.1 - 2.5e-34 119.2 13.8 2.6e-33 115.8 3.7 8.0 1 1 7 8 8 8 4 Mediator complex subunit 3 fungal Exonuc_VII_L PF02601.15 CAR29483.1 - 0.073 12.6 29.6 0.44 10.1 10.3 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF572 PF04502.13 CAR29483.1 - 1.7 8.2 21.5 1.2 8.7 5.4 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) CCSAP PF15748.5 CAR29483.1 - 3 8.0 32.7 1.5 8.9 10.5 2.2 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF4746 PF15928.5 CAR29483.1 - 5.9 6.2 11.9 1.6 8.1 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) EDR1 PF14381.6 CAR29484.1 - 0.032 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Formyl_trans_N PF00551.19 CAR29485.1 - 2e-32 112.4 0.0 3e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CAR29485.1 - 8.3e-09 35.6 0.0 1.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Acyltransferase PF01553.21 CAR29486.1 - 2.4e-09 36.9 0.0 1.2e-08 34.6 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase GPDPase_memb PF10110.9 CAR29486.1 - 0.013 14.3 4.2 0.021 13.6 4.2 1.2 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase MarR_2 PF12802.7 CAR29486.1 - 0.16 11.9 0.4 0.42 10.5 0.4 1.6 1 0 0 1 1 1 0 MarR family FYVE PF01363.21 CAR29487.1 - 8.1e-14 51.5 4.3 2.4e-13 50.0 4.3 1.9 1 0 0 1 1 1 1 FYVE zinc finger STT3 PF02516.14 CAR29488.1 - 7.4e-150 500.1 48.7 8.5e-149 496.6 48.7 2.0 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Haspin_kinase PF12330.8 CAR29490.1 - 8.7e-143 475.7 4.2 8.7e-143 475.7 4.2 2.7 4 0 0 4 4 4 1 Haspin like kinase domain CHD5 PF04420.14 CAR29491.1 - 4.4e-45 153.4 0.2 4.4e-45 153.4 0.2 1.3 2 0 0 2 2 2 1 CHD5-like protein DUF3584 PF12128.8 CAR29491.1 - 0.021 12.4 2.0 0.028 12.0 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-H PF05837.12 CAR29491.1 - 0.083 13.3 1.0 0.14 12.6 1.0 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) CK_II_beta PF01214.18 CAR29492.1 - 1.2e-67 227.3 0.1 2.4e-67 226.3 0.1 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit HSCB_C PF07743.13 CAR29493.1 - 8.9e-19 67.8 0.1 6.9e-18 64.9 0.6 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CAR29493.1 - 2.2e-06 27.7 0.1 7.4e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 DnaJ domain HTH_57 PF18679.1 CAR29493.1 - 0.026 14.8 0.6 0.24 11.7 0.0 2.1 1 1 1 2 2 2 0 ThcOx helix turn helix domain UVR PF02151.19 CAR29493.1 - 0.042 13.6 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif NifW PF03206.14 CAR29493.1 - 0.11 13.1 0.1 2.4 8.7 0.0 2.6 1 1 0 2 2 2 0 Nitrogen fixation protein NifW Pox_A_type_inc PF04508.12 CAR29493.1 - 1.3 9.0 4.7 0.23 11.4 0.6 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ATE_C PF04377.15 CAR29494.1 - 1.3e-44 152.1 0.4 9.6e-44 149.3 0.3 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CAR29494.1 - 6.8e-26 90.5 2.5 1.3e-25 89.6 2.5 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DUF3361 PF11841.8 CAR29495.1 - 0.0064 16.4 3.0 0.049 13.6 0.1 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3361) WD40 PF00400.32 CAR29496.1 - 3.4e-30 103.6 8.8 7.9e-09 36.0 0.0 7.5 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29496.1 - 3.7e-13 49.6 0.0 0.23 11.8 0.0 6.0 3 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 CAR29496.1 - 4.9e-08 32.6 0.0 1.5e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 HIRA B motif Hira PF07569.11 CAR29496.1 - 1e-07 31.9 0.0 2.6e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split PD40 PF07676.12 CAR29496.1 - 3.7e-06 26.7 0.0 0.36 10.8 0.0 4.3 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 CAR29496.1 - 0.00051 20.0 0.1 1.7 8.5 0.0 4.1 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR29496.1 - 0.0038 16.2 0.5 0.11 11.5 0.0 2.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CAR29496.1 - 0.021 14.2 0.0 0.065 12.6 0.0 1.9 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 CAR29496.1 - 0.058 12.7 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 WD40-like domain Aconitase PF00330.20 CAR29497.1 - 3.8e-160 533.9 0.6 4.6e-160 533.6 0.6 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CAR29497.1 - 1.6e-45 154.6 0.0 5.6e-45 152.9 0.0 1.9 2 0 0 2 2 2 1 Aconitase C-terminal domain SH3_1 PF00018.28 CAR29498.1 - 1.8e-35 120.2 5.2 6.7e-12 44.8 0.0 4.4 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 CAR29498.1 - 1e-32 111.7 8.3 2.6e-12 46.4 0.3 4.1 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 CAR29498.1 - 2.9e-31 107.1 0.0 4.9e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 CAR29498.1 - 5.3e-28 96.5 0.0 2.2e-09 36.8 0.0 4.7 4 0 0 4 4 4 4 Variant SH3 domain SH3_10 PF17902.1 CAR29498.1 - 7.5e-06 25.9 0.2 3.4 7.8 0.0 4.3 4 0 0 4 4 4 2 SH3 domain SAM_4 PF18017.1 CAR29498.1 - 0.00042 20.2 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CAR29498.1 - 0.083 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF962 PF06127.11 CAR29499.1 - 1.9e-24 85.6 4.9 1e-23 83.2 4.9 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Cytochrom_B_C PF00032.17 CAR29499.1 - 0.15 12.4 1.5 0.66 10.3 1.5 2.0 1 1 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD DUF1056 PF06341.11 CAR29499.1 - 0.36 11.2 4.3 0.14 12.5 1.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1056) Proteasome PF00227.26 CAR29500.1 - 3.3e-42 144.1 0.0 5e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CAR29500.1 - 2.2e-15 56.0 0.1 3.8e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Rsc14 PF08586.10 CAR29501.1 - 1.2e-41 141.5 1.1 1.3e-41 141.4 0.4 1.5 2 0 0 2 2 2 1 RSC complex, Rsc14/Ldb7 subunit zf-BED PF02892.15 CAR29501.1 - 0.025 14.6 1.5 0.053 13.5 1.5 1.5 1 0 0 1 1 1 0 BED zinc finger zf-AN1 PF01428.16 CAR29501.1 - 0.026 14.7 1.5 0.049 13.8 1.5 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger ERG4_ERG24 PF01222.17 CAR29502.1 - 4.7e-180 599.0 30.9 5.3e-180 598.8 30.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Fungal_trans PF04082.18 CAR29504.1 - 2.1e-31 108.9 6.8 2.1e-31 108.9 6.8 1.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR29504.1 - 1.2e-07 31.7 10.8 3e-07 30.4 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med9 PF07544.13 CAR29504.1 - 0.064 13.4 3.2 0.28 11.3 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PUF PF00806.19 CAR29505.1 - 9.8e-61 198.2 14.2 5.5e-09 35.2 0.4 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 CAR29505.1 - 0.0055 17.1 0.2 4.1 7.7 0.0 3.6 1 1 2 3 3 3 2 CPL (NUC119) domain E1-E2_ATPase PF00122.20 CAR29506.1 - 3.9e-48 163.4 4.9 8e-48 162.3 3.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CAR29506.1 - 2.5e-19 70.4 0.1 7.2e-19 68.9 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CAR29506.1 - 2e-10 40.2 0.0 4.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAR29506.1 - 0.0031 17.3 0.1 0.0057 16.4 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAR29506.1 - 0.0032 17.5 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) O-antigen_lig PF13425.6 CAR29506.1 - 0.3 9.8 5.9 0.67 8.7 5.9 1.5 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ADH_N PF08240.12 CAR29507.1 - 6.9e-20 71.0 7.5 1.1e-19 70.3 7.5 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CAR29507.1 - 1.1e-18 67.5 0.0 2.1e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CAR29507.1 - 1.3e-05 24.6 0.0 2.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CAR29507.1 - 3.6e-05 23.2 0.1 6.8e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CAR29507.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 CAR29507.1 - 0.34 10.8 0.8 0.99 9.3 0.8 1.7 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA_int_endo PF01974.17 CAR29508.1 - 3.5e-18 65.4 0.0 7.8e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain E1-E2_ATPase PF00122.20 CAR29509.1 - 2.2e-39 134.9 0.6 2.2e-39 134.9 0.6 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CAR29509.1 - 3.4e-38 131.2 3.9 3.4e-38 131.2 3.9 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CAR29509.1 - 3.9e-19 68.5 0.0 1e-18 67.2 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CAR29509.1 - 1e-14 55.4 1.1 1.5e-13 51.5 1.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CAR29509.1 - 4e-11 42.4 0.0 1.2e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAR29509.1 - 8.9e-05 22.3 6.3 0.00056 19.7 1.3 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase TMF_TATA_bd PF12325.8 CAR29510.1 - 0.011 15.9 0.2 0.011 15.9 0.2 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Syntaxin-6_N PF09177.11 CAR29510.1 - 0.024 15.2 8.9 1.1 9.8 0.8 3.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.11 CAR29510.1 - 0.097 12.9 8.1 0.21 11.9 0.3 3.3 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF1054 PF06335.12 CAR29510.1 - 0.12 12.3 1.9 0.51 10.2 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1054) DASH_Dad3 PF08656.10 CAR29510.1 - 0.13 12.3 0.3 0.13 12.3 0.3 2.8 2 1 1 3 3 3 0 DASH complex subunit Dad3 ExsD PF16806.5 CAR29510.1 - 0.15 11.9 3.2 0.79 9.6 0.2 2.4 1 1 1 2 2 2 0 Antiactivator protein ExsD Sec34 PF04136.15 CAR29510.1 - 0.22 11.4 10.1 0.15 12.0 3.5 2.9 2 1 1 3 3 3 0 Sec34-like family DUF1664 PF07889.12 CAR29510.1 - 0.25 11.4 4.9 0.36 10.9 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CAR29510.1 - 0.43 10.7 10.9 1.5 9.0 0.6 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 CAR29510.1 - 1.2 9.7 6.5 14 6.3 0.1 2.9 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Takusan PF04822.13 CAR29510.1 - 1.3 8.9 8.2 2.3 8.2 0.4 3.1 3 0 0 3 3 3 0 Takusan NPV_P10 PF05531.12 CAR29510.1 - 2 9.0 8.6 0.88 10.1 2.6 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein FlxA PF14282.6 CAR29510.1 - 6.7 6.8 7.8 11 6.0 0.2 3.0 2 1 1 3 3 3 0 FlxA-like protein WD40 PF00400.32 CAR29511.1 - 1.7e-19 69.8 1.1 9.2e-07 29.5 0.0 6.0 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29511.1 - 4.6e-06 26.8 0.0 0.4 11.0 0.0 4.0 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR29511.1 - 0.0035 17.3 0.0 4 7.3 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Rep_fac-A_C PF08646.10 CAR29512.1 - 2.3e-58 196.1 0.8 1.3e-55 187.2 0.5 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CAR29512.1 - 7.5e-34 115.6 1.3 1.8e-30 104.7 0.1 4.0 4 0 0 4 4 4 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 CAR29512.1 - 6.1e-15 55.0 0.1 7.9e-07 29.0 0.0 4.5 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 CAR29512.1 - 0.00031 20.7 0.4 0.00097 19.1 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain CDC24_OB3 PF17244.2 CAR29512.1 - 0.00037 20.3 0.2 0.0046 16.7 0.0 2.8 3 1 0 3 3 3 1 Cell division control protein 24, OB domain 3 BRCA-2_OB1 PF09103.10 CAR29512.1 - 0.047 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 DUF4539 PF15072.6 CAR29512.1 - 0.15 12.2 0.0 1.3 9.1 0.0 2.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4539) Zn_clus PF00172.18 CAR29513.1 - 0.001 19.1 6.4 0.0019 18.3 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CAR29513.1 - 0.0029 16.7 0.6 0.0029 16.7 0.6 2.6 2 1 1 3 3 3 1 Fungal specific transcription factor domain WD40 PF00400.32 CAR29514.1 - 9e-20 70.6 5.6 0.0015 19.3 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29514.1 - 4e-15 55.9 4.2 8.4e-08 32.4 0.1 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR29514.1 - 2.5e-06 27.5 0.3 0.0013 18.7 0.1 3.0 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CAR29515.1 - 1.4e-13 51.1 2.4 1.4e-06 28.9 0.5 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29515.1 - 2e-08 34.4 1.2 0.029 14.6 0.1 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CAR29515.1 - 0.048 12.0 0.0 0.14 10.5 0.0 1.6 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 CAR29515.1 - 0.08 12.9 0.0 6.8 6.8 0.1 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat EMP24_GP25L PF01105.24 CAR29516.1 - 5.3e-48 163.4 0.9 6.5e-48 163.1 0.9 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_UL73 PF03554.13 CAR29516.1 - 0.16 12.0 0.7 0.32 11.0 0.7 1.4 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein 3Beta_HSD PF01073.19 CAR29518.1 - 3.1e-86 288.9 0.0 3.7e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CAR29518.1 - 3e-29 102.2 0.0 3.9e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAR29518.1 - 7.6e-18 65.0 0.0 2.9e-17 63.1 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CAR29518.1 - 4.7e-12 45.6 0.1 7.2e-11 41.7 0.1 2.3 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 CAR29518.1 - 2.3e-09 36.8 0.0 3.7e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CAR29518.1 - 5.3e-09 36.2 0.0 7.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CAR29518.1 - 6.1e-06 25.6 0.0 1.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CAR29518.1 - 8.1e-05 22.3 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 CAR29518.1 - 0.00045 20.2 0.0 0.0039 17.1 0.0 2.2 1 1 0 1 1 1 1 KR domain N6-adenineMlase PF10237.9 CAR29519.1 - 8.8e-51 171.9 0.0 1.3e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase PTS_IIA PF02255.16 CAR29519.1 - 0.2 11.7 1.3 0.37 10.9 1.3 1.3 1 0 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit B-block_TFIIIC PF04182.12 CAR29520.1 - 1.5e-15 57.1 0.2 8.4e-15 54.7 0.0 2.3 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC Vps8 PF12816.7 CAR29521.1 - 4.1e-56 189.6 0.1 4.1e-56 189.6 0.1 2.4 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 CAR29521.1 - 0.0007 19.5 11.9 0.0012 18.8 0.5 3.6 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 CAR29521.1 - 0.001 19.0 1.7 0.0031 17.4 1.8 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CAR29521.1 - 0.0055 16.6 1.2 0.016 15.0 1.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR29521.1 - 0.016 15.6 1.1 0.016 15.6 1.1 2.5 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 CAR29521.1 - 0.021 14.9 1.3 0.056 13.5 1.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 CAR29521.1 - 0.023 15.0 1.3 0.078 13.3 0.4 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain PHD PF00628.29 CAR29521.1 - 0.056 13.3 0.6 0.16 11.9 0.6 1.8 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 CAR29521.1 - 1.4 9.1 4.0 0.8 9.9 0.9 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger zf-C3HC4_2 PF13923.6 CAR29521.1 - 1.8 8.5 5.3 0.48 10.3 1.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAR29521.1 - 2.4 8.0 7.2 0.11 12.2 1.0 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-C3H2C3 PF17122.5 CAR29521.1 - 2.7 8.1 5.4 0.48 10.5 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger zf-ANAPC11 PF12861.7 CAR29521.1 - 3 7.9 6.0 0.55 10.3 0.3 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger EF1_GNE PF00736.19 CAR29523.1 - 5.6e-30 103.4 1.4 1.2e-29 102.3 1.4 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CAR29523.1 - 9.5e-13 48.3 7.9 2.4e-12 47.1 7.9 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 CAR29523.1 - 0.011 15.7 0.0 0.04 13.9 0.0 1.8 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain eIF-3c_N PF05470.12 CAR29523.1 - 0.11 10.8 4.4 0.12 10.7 4.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus GST_C PF00043.25 CAR29523.1 - 0.18 12.0 3.6 1.8 8.8 0.3 2.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SNF5 PF04855.12 CAR29525.1 - 6.3e-49 166.9 0.8 1.2e-26 94.0 0.1 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 Cnl2_NKP2 PF09447.10 CAR29526.1 - 0.0019 18.3 2.8 0.0029 17.7 0.8 2.2 3 0 0 3 3 3 1 Cnl2/NKP2 family protein DUF2200 PF09966.9 CAR29526.1 - 0.047 13.8 0.9 0.19 11.9 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) Elongin_A PF06881.11 CAR29526.1 - 0.27 11.8 6.7 0.15 12.6 4.2 1.8 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Fib_alpha PF08702.10 CAR29526.1 - 2.8 8.1 6.5 2.8 8.1 3.5 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family dCMP_cyt_deam_1 PF00383.23 CAR29527.1 - 6.3e-08 32.4 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CAR29527.1 - 0.00011 22.0 0.3 0.00023 20.9 0.3 1.5 1 0 0 1 1 1 1 MafB19-like deaminase Telomerase_RBD PF12009.8 CAR29528.1 - 1.8e-30 105.8 5.5 5.1e-30 104.3 5.5 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CAR29528.1 - 2.1e-08 33.9 0.1 8.8e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) AIP3 PF03915.13 CAR29529.1 - 4.4e-136 454.2 16.8 9.2e-136 453.1 16.8 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 Mus7 PF09462.10 CAR29530.1 - 3.5e-15 55.9 4.4 3.5e-15 55.9 4.4 2.9 2 1 0 3 3 3 2 Mus7/MMS22 family SANT_DAMP1_like PF16282.5 CAR29531.1 - 1.1e-27 96.0 5.2 5e-27 93.9 5.2 2.2 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 CAR29531.1 - 0.0006 20.0 0.5 0.0006 20.0 0.5 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain DMAP1_like PF17024.5 CAR29531.1 - 0.0014 18.7 0.1 0.0043 17.2 0.1 2.0 1 0 0 1 1 1 1 Putative DMAP1-like Myb_DNA-binding PF00249.31 CAR29531.1 - 0.0085 16.3 0.2 0.028 14.6 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain SAM_3 PF18016.1 CAR29531.1 - 0.073 12.9 0.5 2.6 7.9 0.4 2.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) E_Pc_C PF06752.12 CAR29531.1 - 3.2 7.8 13.5 2.3 8.2 11.5 1.8 2 0 0 2 2 2 0 Enhancer of Polycomb C-terminus Cullin PF00888.22 CAR29532.1 - 3.2e-135 452.2 21.9 3.2e-135 452.2 21.9 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CAR29532.1 - 1.4e-18 66.7 1.6 1.4e-18 66.7 1.6 2.7 3 0 0 3 3 3 1 Cullin protein neddylation domain Phage_rep_O PF04492.13 CAR29532.1 - 0.72 10.5 4.3 13 6.5 0.2 3.6 3 1 1 4 4 4 0 Bacteriophage replication protein O SF3a60_bindingd PF12108.8 CAR29532.1 - 0.93 9.4 3.5 0.66 9.9 0.1 2.3 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain zf-CCCH PF00642.24 CAR29533.1 - 3.9e-10 39.4 2.2 9.6e-10 38.1 2.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 CAR29533.1 - 3e-09 36.6 6.6 5.8e-09 35.7 6.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR29533.1 - 4.6e-08 32.8 8.8 4.6e-08 32.8 8.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR29533.1 - 1e-07 31.8 9.6 2.2e-07 30.7 9.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CAR29533.1 - 3.6e-07 30.1 5.7 3.6e-07 30.1 5.7 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CAR29533.1 - 1.6e-06 27.9 9.9 3.7e-06 26.7 9.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 CAR29533.1 - 1.6e-06 27.9 5.6 3.8e-06 26.8 5.6 1.7 1 0 0 1 1 1 1 Zinc finger domain Prok-RING_4 PF14447.6 CAR29533.1 - 2.9e-06 27.0 7.1 7.2e-06 25.8 7.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CAR29533.1 - 3.3e-06 27.3 8.1 7.8e-06 26.1 8.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 CAR29533.1 - 0.00012 21.8 1.8 0.00029 20.6 1.8 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-RING_10 PF16685.5 CAR29533.1 - 0.00057 20.0 6.9 0.00057 20.0 6.9 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 CAR29533.1 - 0.0017 18.5 8.6 0.0017 18.5 8.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CAR29533.1 - 0.012 15.9 3.9 0.037 14.3 3.9 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-CCCH_2 PF14608.6 CAR29533.1 - 0.026 15.0 2.9 0.11 13.0 2.9 2.1 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-P11 PF03854.14 CAR29533.1 - 0.12 12.1 4.4 0.24 11.1 4.4 1.5 1 0 0 1 1 1 0 P-11 zinc finger Pex24p PF06398.11 CAR29534.1 - 3.1e-96 322.6 11.3 4.1e-96 322.2 11.3 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin SOG2 PF10428.9 CAR29534.1 - 0.12 11.5 5.5 0.19 10.9 5.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MAGI_u1 PF16663.5 CAR29534.1 - 0.16 12.1 5.0 0.058 13.5 2.0 1.9 2 0 0 2 2 2 0 Unstructured region on MAGI Ribosomal_L38e PF01781.18 CAR29535.1 - 1.9e-27 95.1 2.2 2.1e-27 95.0 2.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIIF_beta_N PF17683.1 CAR29536.1 - 4.1e-35 121.4 8.0 1.5e-34 119.6 8.0 2.0 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 CAR29536.1 - 2.4e-27 94.9 0.7 4.1e-27 94.1 0.7 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 CAR29536.1 - 0.0026 18.6 0.2 0.0026 18.6 0.2 2.3 1 1 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Prp18 PF02840.15 CAR29537.1 - 4e-38 130.7 0.0 1.5e-37 128.8 0.0 1.8 1 1 1 2 2 2 1 Prp18 domain DUF4112 PF13430.6 CAR29538.1 - 2e-27 95.5 0.6 2.7e-27 95.1 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2057 PF09829.9 CAR29538.1 - 0.49 10.5 5.9 0.99 9.5 5.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF2457 PF10446.9 CAR29538.1 - 5.7 6.0 8.1 9.1 5.3 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CTP_transf_like PF01467.26 CAR29539.1 - 1.9e-23 83.3 0.1 5.2e-19 68.9 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CAR29539.1 - 0.012 15.5 0.5 7 6.5 0.1 3.3 3 0 0 3 3 3 0 FAD synthetase HABP4_PAI-RBP1 PF04774.15 CAR29540.1 - 0.01 16.7 0.2 0.014 16.2 0.2 1.3 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family CTP_transf_like PF01467.26 CAR29541.1 - 8.8e-31 107.0 0.0 1.7e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF2281 PF10047.9 CAR29542.1 - 0.049 14.3 0.3 0.067 13.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) PALP PF00291.25 CAR29543.1 - 4.5e-67 226.5 0.0 5.3e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PWI PF01480.17 CAR29544.1 - 0.0053 17.1 0.2 0.024 15.0 0.2 2.1 2 0 0 2 2 2 1 PWI domain Mucin PF01456.17 CAR29544.1 - 0.04 13.9 9.5 0.071 13.1 9.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 CAR29544.1 - 0.14 12.2 6.0 0.26 11.2 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 CAR29544.1 - 0.21 9.7 6.2 0.28 9.3 6.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Abhydrolase_1 PF00561.20 CAR29546.1 - 1.5e-14 54.3 0.0 3.6e-14 53.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CAR29546.1 - 5.6e-12 46.7 0.0 7.8e-12 46.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR29546.1 - 4.8e-05 22.7 0.0 6.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CAR29546.1 - 0.00013 22.2 0.0 0.0002 21.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF726 PF05277.12 CAR29546.1 - 0.0054 15.7 0.0 0.0086 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) PGAP1 PF07819.13 CAR29546.1 - 0.0059 16.4 0.1 0.017 14.9 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein BAAT_C PF08840.11 CAR29546.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.16 CAR29546.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 CAR29546.1 - 0.15 11.7 0.0 0.95 9.1 0.0 2.1 1 1 0 2 2 2 0 Serine hydrolase (FSH1) DUF5319 PF17252.2 CAR29547.1 - 0.15 12.3 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5319) MMR_HSR1_Xtn PF16897.5 CAR29549.1 - 2.9e-36 123.7 1.3 5.4e-36 122.8 1.3 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CAR29549.1 - 6.6e-20 71.3 0.2 1.9e-19 69.8 0.1 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 CAR29549.1 - 7.1e-20 70.8 0.0 1.7e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CAR29549.1 - 4.7e-13 48.9 0.0 8.9e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 CAR29549.1 - 0.0079 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 CAR29549.1 - 0.0094 16.2 0.3 0.26 11.5 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CAR29549.1 - 0.016 15.3 0.4 2.7 8.0 0.0 2.5 1 1 1 2 2 2 0 Dynamin family MCM PF00493.23 CAR29549.1 - 0.019 14.1 0.1 0.081 12.0 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain SRPRB PF09439.10 CAR29549.1 - 0.022 14.2 0.2 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CAR29549.1 - 0.032 14.6 0.2 0.095 13.1 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 CAR29549.1 - 0.13 11.8 0.4 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Ras family RsgA_GTPase PF03193.16 CAR29549.1 - 0.41 10.5 2.3 8.2 6.3 0.2 2.9 2 2 1 3 3 3 0 RsgA GTPase ETF PF01012.21 CAR29550.1 - 2.6e-40 138.3 0.1 3e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Mvb12 PF09452.10 CAR29551.1 - 2.6e-33 114.3 0.5 2.9e-33 114.2 0.5 1.0 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 3-HAO PF06052.12 CAR29552.1 - 1e-64 216.7 0.0 1.2e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 CAR29552.1 - 0.0034 17.1 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain DUF4379 PF14311.6 CAR29552.1 - 0.01 16.2 0.7 0.031 14.6 0.7 1.8 1 1 0 1 1 1 0 Probable Zinc-ribbon domain zf-ACC PF17848.1 CAR29552.1 - 0.012 15.6 1.5 4.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain GFA PF04828.14 CAR29552.1 - 0.026 14.9 0.2 2 8.8 0.0 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 CAR29552.1 - 0.072 13.0 0.6 11 6.1 0.2 2.6 2 0 0 2 2 2 0 Nudix N-terminal Rpr2 PF04032.16 CAR29552.1 - 0.21 11.9 1.7 11 6.4 0.2 2.2 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Aldolase_II PF00596.21 CAR29553.1 - 4.8e-42 144.0 0.0 5.7e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LSM PF01423.22 CAR29554.1 - 8e-10 38.3 0.1 1.5e-09 37.4 0.1 1.5 1 1 0 1 1 1 1 LSM domain DUF3255 PF11631.8 CAR29554.1 - 0.0059 16.5 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3255) AAA_16 PF13191.6 CAR29555.1 - 0.0035 17.8 0.0 0.0062 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain PRK PF00485.18 CAR29555.1 - 0.0069 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CAR29555.1 - 0.011 16.2 0.0 0.029 14.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CAR29555.1 - 0.016 15.3 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CAR29555.1 - 0.019 14.2 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 CAR29555.1 - 0.022 15.0 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CAR29555.1 - 0.023 15.1 0.0 0.039 14.4 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SMC_N PF02463.19 CAR29555.1 - 0.028 13.9 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 CAR29555.1 - 0.04 14.3 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CAR29555.1 - 0.08 13.3 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CAR29555.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 CAR29555.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein 4HBT_3 PF13622.6 CAR29556.1 - 2.2e-34 119.9 0.0 2.7e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CAR29556.1 - 4.2e-31 107.5 0.1 2.1e-25 89.1 0.2 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase FTHFS PF01268.19 CAR29557.1 - 8.5e-252 836.3 0.2 8.5e-252 836.3 0.2 1.3 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CAR29557.1 - 1e-60 203.7 0.4 2e-60 202.7 0.0 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CAR29557.1 - 3.5e-37 127.2 1.1 7.9e-37 126.1 1.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.21 CAR29557.1 - 0.016 15.3 0.9 0.38 10.8 0.4 2.8 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CbiA PF01656.23 CAR29557.1 - 0.038 14.0 0.0 0.23 11.5 0.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GSHPx PF00255.19 CAR29557.1 - 0.055 13.0 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione peroxidase Helicase_C_4 PF13871.6 CAR29557.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain on Strawberry notch homologue GTP_EFTU PF00009.27 CAR29557.1 - 0.12 11.9 0.3 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Rotamase PF00639.21 CAR29558.1 - 1.1e-26 93.5 0.1 1.5e-26 93.1 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CAR29558.1 - 9.9e-23 80.9 0.0 1.5e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CAR29558.1 - 3.9e-08 33.2 1.3 6.8e-08 32.5 1.3 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 CAR29558.1 - 8.1e-08 33.1 0.0 1.1e-07 32.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain X8 PF07983.13 CAR29558.1 - 0.2 12.4 0.0 0.32 11.7 0.0 1.3 1 0 0 1 1 1 0 X8 domain Rhodanese PF00581.20 CAR29559.1 - 1.1e-09 38.7 0.0 1.3e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain CTP_transf_like PF01467.26 CAR29560.1 - 2e-32 112.4 0.4 5.8e-32 110.8 0.0 2.0 3 0 0 3 3 3 1 Cytidylyltransferase-like Trefoil PF00088.18 CAR29560.1 - 0.18 11.8 0.2 0.33 10.9 0.2 1.4 1 0 0 1 1 1 0 Trefoil (P-type) domain DDHD PF02862.17 CAR29560.1 - 0.3 11.2 5.2 0.51 10.5 0.2 2.2 2 0 0 2 2 2 0 DDHD domain DUF4746 PF15928.5 CAR29560.1 - 0.94 8.8 8.7 1.9 7.8 8.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4834 PF16118.5 CAR29560.1 - 5.3 8.1 16.0 3.1 8.8 8.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ILVD_EDD PF00920.21 CAR29561.1 - 9.2e-207 687.7 0.1 1.1e-206 687.5 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family WD40 PF00400.32 CAR29562.1 - 2.9e-33 113.4 26.1 8.9e-07 29.5 0.0 11.3 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29562.1 - 2.2e-10 40.7 6.8 0.087 13.1 0.2 7.6 5 4 3 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CAR29562.1 - 0.0002 20.8 0.1 0.0061 15.9 0.0 2.5 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 CAR29562.1 - 0.00097 18.2 0.0 0.91 8.4 0.0 3.8 5 0 0 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PMT PF02366.18 CAR29563.1 - 4.8e-91 304.7 15.4 4.8e-91 304.7 15.4 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CAR29563.1 - 5.3e-54 182.8 19.8 5.3e-54 182.8 19.8 2.5 2 1 2 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CAR29563.1 - 9.6e-20 71.2 0.2 1.7e-19 70.4 0.2 1.3 1 0 0 1 1 1 1 MIR domain Thi4 PF01946.17 CAR29565.1 - 7.5e-105 349.4 0.1 8.9e-105 349.1 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CAR29565.1 - 1.1e-05 25.2 0.0 1.5e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CAR29565.1 - 2.5e-05 24.3 0.1 0.00021 21.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CAR29565.1 - 4.3e-05 23.7 0.1 9.8e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CAR29565.1 - 0.00019 20.6 0.2 0.0003 20.0 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CAR29565.1 - 0.00072 18.7 1.2 0.0075 15.4 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CAR29565.1 - 0.0047 16.2 0.0 0.0082 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAR29565.1 - 0.011 14.4 0.2 0.023 13.4 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CAR29565.1 - 0.014 14.6 0.0 0.032 13.5 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAR29565.1 - 0.028 13.8 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase TPR_14 PF13428.6 CAR29566.1 - 0.0014 19.2 0.0 5.2 8.2 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CAR29566.1 - 0.0073 16.8 0.5 5 7.7 0.2 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAR29566.1 - 0.025 14.7 3.2 22 5.5 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat PPTA PF01239.22 CAR29566.1 - 0.041 13.6 1.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat HrpB1_HrpK PF09613.10 CAR29566.1 - 0.12 12.0 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) SUI1 PF01253.22 CAR29567.1 - 3.2e-22 78.8 0.7 6.1e-22 77.9 0.7 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 IF-2 PF11987.8 CAR29567.1 - 0.024 14.8 0.5 0.067 13.3 0.5 1.7 1 0 0 1 1 1 0 Translation-initiation factor 2 RNase_PH PF01138.21 CAR29569.1 - 1.1e-27 97.1 0.0 1.9e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CAR29569.1 - 0.0012 18.8 0.2 0.0028 17.6 0.2 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.13 CAR29570.1 - 9.5e-85 284.6 18.3 1.6e-84 283.9 18.3 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CAR29570.1 - 1.4e-08 34.2 12.0 1.4e-08 34.2 12.0 2.0 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 CAR29570.1 - 0.00014 21.7 12.0 0.00014 21.7 12.0 1.8 1 1 1 2 2 2 1 Glycosyltransferase family 87 PMT_2 PF13231.6 CAR29570.1 - 1.1 9.4 22.7 0.048 13.9 14.7 2.3 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF5572 PF17733.1 CAR29571.1 - 7.6e-09 35.3 0.2 1.2e-08 34.6 0.2 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Mito_carr PF00153.27 CAR29572.1 - 1e-51 172.8 4.2 1.3e-17 63.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SPC12 PF06645.13 CAR29574.1 - 3.1e-23 81.6 0.4 3.8e-23 81.4 0.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) FeoB_associated PF12669.7 CAR29574.1 - 4.3 7.8 5.0 6.4 7.3 0.5 2.1 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein FGGY_N PF00370.21 CAR29575.1 - 5.3e-24 85.1 0.0 3.4e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CAR29575.1 - 2.3e-09 37.2 0.0 1.5e-08 34.6 0.0 2.4 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Biotin_lipoyl PF00364.22 CAR29576.1 - 6.3e-18 64.4 1.4 6.3e-18 64.4 1.4 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 CAR29576.1 - 4.2e-05 23.8 0.1 0.0001 22.5 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CAR29576.1 - 0.00018 21.3 0.3 0.00018 21.3 0.3 3.0 2 1 1 3 3 3 1 Biotin-lipoyl like Rxt3 PF08642.10 CAR29576.1 - 0.0017 19.1 0.1 0.069 13.9 0.0 2.3 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 HlyD_3 PF13437.6 CAR29576.1 - 0.0039 17.9 0.8 1.7 9.4 0.1 3.0 3 0 0 3 3 3 1 HlyD family secretion protein SAF PF08666.12 CAR29576.1 - 0.14 12.8 0.7 3.4 8.4 0.0 2.7 2 1 1 3 3 3 0 SAF domain ATP-sulfurylase PF01747.17 CAR29577.1 - 1.3e-84 282.9 0.0 1.7e-84 282.5 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 CAR29577.1 - 1.3e-48 164.7 0.0 2.2e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain CTP_transf_like PF01467.26 CAR29577.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 1 0 1 1 1 0 Cytidylyltransferase-like Gp_dh_C PF02800.20 CAR29578.1 - 8e-72 240.0 0.0 1.2e-71 239.4 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CAR29578.1 - 4.9e-37 126.3 0.0 1e-36 125.3 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CAR29578.1 - 0.0056 16.8 0.5 0.021 15.0 0.2 2.2 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus ThiS-like PF14453.6 CAR29578.1 - 0.18 11.9 0.2 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 ThiS-like ubiquitin Memo PF01875.17 CAR29579.1 - 9.7e-88 293.8 0.0 1.1e-87 293.6 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein EIF_2_alpha PF07541.12 CAR29580.1 - 4e-38 130.1 1.0 6.1e-38 129.5 0.2 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CAR29580.1 - 4.4e-15 55.8 2.6 6.5e-15 55.2 1.4 1.9 2 0 0 2 2 2 1 S1 RNA binding domain EXOSC1 PF10447.9 CAR29580.1 - 0.23 12.1 3.3 0.33 11.6 0.4 2.3 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Rap_GAP PF02145.15 CAR29581.1 - 1.9e-37 128.6 1.3 3.8e-37 127.7 1.3 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 CAR29581.1 - 1e-17 64.3 0.0 2e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Tuberin DUF3384 PF11864.8 CAR29581.1 - 1.7e-07 30.6 1.4 6.5e-07 28.6 1.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3384) Glyco_hydro_16 PF00722.21 CAR29583.1 - 7.7e-47 159.0 1.0 7.7e-47 159.0 1.0 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 FAM196 PF15265.6 CAR29583.1 - 1.2 8.6 25.0 1.5 8.2 25.0 1.1 1 0 0 1 1 1 0 FAM196 family RNA_pol_Rpb4 PF03874.16 CAR29584.1 - 7.1e-34 116.8 3.6 8.4e-34 116.6 3.6 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Pex19 PF04614.12 CAR29584.1 - 0.022 14.6 1.4 0.022 14.5 0.9 1.3 1 1 0 1 1 1 0 Pex19 protein family Nop PF01798.18 CAR29584.1 - 0.033 13.7 1.6 0.042 13.3 1.6 1.1 1 0 0 1 1 1 0 snoRNA binding domain, fibrillarin DUF4476 PF14771.6 CAR29584.1 - 0.068 13.5 0.9 1.6 9.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) PRC2_HTH_1 PF18118.1 CAR29584.1 - 2.1 9.2 5.5 2.9 8.7 0.1 2.2 1 1 1 2 2 2 0 Polycomb repressive complex 2 tri-helical domain VTC PF09359.10 CAR29585.1 - 9.3e-101 336.8 0.1 1.4e-100 336.2 0.1 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 CAR29585.1 - 5.3e-10 39.8 16.4 1.1e-05 25.6 0.4 3.8 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 CAR29585.1 - 1.1e-09 38.6 6.1 1.1e-09 38.6 6.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Mad3_BUB1_I PF08311.12 CAR29586.1 - 1.1e-43 148.2 3.6 2e-43 147.3 0.9 2.4 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 CAR29586.1 - 1.9e-27 95.2 0.5 1.1e-26 92.7 0.1 2.4 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 CAR29586.1 - 1.7e-16 60.4 0.0 3.2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Mad3_BUB1_I_2 PF17014.5 CAR29586.1 - 1.1e-05 25.6 1.3 3e-05 24.1 1.3 1.8 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Pkinase_Tyr PF07714.17 CAR29586.1 - 0.0053 16.1 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RNase_H2-Ydr279 PF09468.10 CAR29586.1 - 0.087 13.0 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Cpn60_TCP1 PF00118.24 CAR29587.1 - 1.7e-161 538.2 3.2 1.9e-161 538.0 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_hydro_44 PF12891.7 CAR29588.1 - 0.1 12.5 0.3 0.17 11.8 0.3 1.3 1 0 0 1 1 1 0 Glycoside hydrolase family 44 Sad1_UNC PF07738.13 CAR29589.1 - 2e-08 34.3 0.1 8.3e-06 25.8 0.0 3.0 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal NleF_casp_inhib PF16809.5 CAR29589.1 - 0.005 16.8 0.1 0.015 15.2 0.1 1.9 1 0 0 1 1 1 1 NleF caspase inhibitor Baculo_PEP_C PF04513.12 CAR29589.1 - 0.084 12.9 1.2 0.19 11.7 0.9 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bot1p PF12298.8 CAR29590.1 - 1.1e-63 214.5 0.3 1.6e-63 214.0 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein AA_permease PF00324.21 CAR29591.1 - 6.4e-123 410.9 34.2 8e-123 410.5 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR29591.1 - 1.1e-35 123.3 31.8 1.4e-35 123.0 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease Desmo_N PF06771.11 CAR29592.1 - 0.096 13.1 0.1 0.14 12.5 0.1 1.3 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus Thioredoxin PF00085.20 CAR29592.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin His_Phos_1 PF00300.22 CAR29593.1 - 1.4e-26 93.4 0.0 2.4e-14 53.5 0.0 3.1 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) TIM PF00121.18 CAR29594.1 - 1.6e-87 292.9 0.0 1.8e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Head-tail_con PF12236.8 CAR29594.1 - 0.0061 15.1 0.0 0.0085 14.6 0.0 1.1 1 0 0 1 1 1 1 Bacteriophage head to tail connecting protein Alg14 PF08660.11 CAR29595.1 - 7.6e-57 192.0 0.1 9.6e-57 191.7 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like SNF2_N PF00176.23 CAR29597.1 - 8.2e-62 208.9 0.0 1.4e-61 208.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR29597.1 - 1.5e-15 57.5 0.0 4.4e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR29597.1 - 4.4e-11 43.1 0.8 3.2e-10 40.3 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CAR29597.1 - 3.2e-09 36.4 3.0 4.4e-08 32.7 2.9 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 CAR29597.1 - 2.4e-05 23.7 0.1 4.3e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 CAR29597.1 - 5.3e-05 23.1 0.1 0.00019 21.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2439 PF10382.9 CAR29597.1 - 0.0014 18.9 0.7 0.0054 17.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) AAA_22 PF13401.6 CAR29597.1 - 0.084 13.2 0.0 0.37 11.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.6 CAR29597.1 - 0.094 12.3 2.0 0.14 11.8 0.2 2.1 2 0 0 2 2 2 0 AAA domain bVLRF1 PF18826.1 CAR29598.1 - 1.1e-55 187.5 0.3 2.3e-55 186.5 0.3 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank PF00023.30 CAR29598.1 - 0.013 15.9 0.1 0.031 14.7 0.1 1.7 1 0 0 1 1 1 0 Ankyrin repeat zf-C2H2_2 PF12756.7 CAR29598.1 - 0.042 14.2 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ank_2 PF12796.7 CAR29598.1 - 0.06 13.9 0.1 0.19 12.3 0.1 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAR29598.1 - 0.1 13.0 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) URO-D PF01208.17 CAR29599.1 - 2.3e-128 428.2 0.0 2.6e-128 428.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Peptidase_M28 PF04389.17 CAR29600.1 - 6.9e-36 123.8 0.0 1.2e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CAR29600.1 - 0.0008 19.2 0.0 0.0013 18.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CAR29600.1 - 0.0028 16.7 0.0 0.012 14.7 0.0 1.7 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase TPR_1 PF00515.28 CAR29601.1 - 6.7e-11 41.5 1.1 0.064 13.1 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CAR29601.1 - 1.6e-10 40.2 2.4 0.76 10.0 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CAR29601.1 - 6.1e-08 32.5 1.7 0.083 13.3 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CAR29601.1 - 2e-06 27.9 0.4 0.16 12.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR29601.1 - 5.5e-06 26.5 0.2 0.044 14.0 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CAR29601.1 - 9.3e-06 26.1 5.5 1.7 9.7 0.0 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR29601.1 - 1.6e-05 25.3 2.5 0.2 12.2 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR29601.1 - 2.3e-05 24.2 4.2 0.66 10.3 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat ChAPs PF09295.10 CAR29601.1 - 0.00022 20.4 1.1 0.023 13.7 0.0 3.0 3 1 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_16 PF13432.6 CAR29601.1 - 0.00038 21.0 1.6 24 5.7 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAR29601.1 - 0.00079 19.7 9.2 8.9 6.7 0.1 6.1 5 2 2 7 7 7 1 Tetratricopeptide repeat Tli4_N PF18443.1 CAR29601.1 - 0.05 14.0 0.0 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Tle cognate immunity protein 4 N-terminal domain TPR_7 PF13176.6 CAR29601.1 - 0.094 12.8 4.8 0.3 11.2 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF627 PF04781.12 CAR29601.1 - 0.14 12.2 1.4 0.9 9.6 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF627) DUF3439 PF11921.8 CAR29601.1 - 0.18 11.8 3.1 0.41 10.6 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TPR_11 PF13414.6 CAR29601.1 - 0.56 9.9 2.4 1.8 8.3 0.3 2.7 2 0 0 2 2 2 0 TPR repeat T3SS_needle_F PF09392.10 CAR29601.1 - 0.94 9.7 3.1 0.78 10.0 0.5 2.3 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF FSA_C PF10479.9 CAR29601.1 - 2.9 5.9 7.0 4.5 5.3 7.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Fungal_trans_2 PF11951.8 CAR29602.1 - 5.7e-06 25.4 0.5 3e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR29602.1 - 2e-05 24.6 12.8 4.1e-05 23.6 12.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 CAR29602.1 - 0.9 10.1 8.7 2.6 8.6 8.7 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Dfp1_Him1_M PF08630.10 CAR29603.1 - 1e-43 148.6 1.4 7.8e-43 145.7 0.0 2.7 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 CAR29603.1 - 4.9e-21 74.6 1.1 9.2e-21 73.7 1.1 1.5 1 0 0 1 1 1 1 DBF zinc finger AAA_14 PF13173.6 CAR29603.1 - 0.058 13.4 0.1 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 CAR29603.1 - 0.097 12.5 0.7 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase SLM4 PF16818.5 CAR29604.1 - 3.5e-62 209.1 0.7 4.1e-62 208.9 0.7 1.0 1 0 0 1 1 1 1 Protein SLM4 UQ_con PF00179.26 CAR29605.1 - 3.8e-44 149.7 0.0 5.2e-44 149.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BUD22 PF09073.10 CAR29605.1 - 0.67 9.2 15.3 0.75 9.1 15.3 1.1 1 0 0 1 1 1 0 BUD22 Amidase PF01425.21 CAR29606.1 - 1.3e-79 268.3 0.0 1.6e-79 268.0 0.0 1.1 1 0 0 1 1 1 1 Amidase YfkD PF14167.6 CAR29606.1 - 0.071 12.3 0.2 0.11 11.7 0.2 1.2 1 0 0 1 1 1 0 YfkD-like protein Recep_L_domain PF01030.24 CAR29607.1 - 0.0015 18.7 11.7 1.1 9.4 0.0 4.2 1 1 3 4 4 4 3 Receptor L domain PCI PF01399.27 CAR29608.1 - 4.6e-11 43.2 0.9 7.2e-10 39.3 0.2 3.1 2 0 0 2 2 2 1 PCI domain AAA PF00004.29 CAR29609.1 - 6.4e-53 178.7 0.0 1.4e-38 132.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 CAR29609.1 - 3e-12 46.2 0.5 2.7e-11 43.1 0.1 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 CAR29609.1 - 3.8e-11 42.6 0.1 1.1e-10 41.1 0.1 1.9 1 1 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CAR29609.1 - 4.3e-09 36.8 0.3 0.00022 21.5 0.0 3.4 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 CAR29609.1 - 9.1e-09 35.0 0.1 0.0029 16.8 0.0 2.4 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_16 PF13191.6 CAR29609.1 - 1.3e-08 35.4 0.1 0.0065 16.9 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 CAR29609.1 - 8.7e-08 32.4 0.0 0.0014 18.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CAR29609.1 - 1.5e-07 31.4 0.0 0.0018 18.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CAR29609.1 - 2.2e-07 30.4 0.0 0.0026 17.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 CAR29609.1 - 2.6e-07 30.5 0.1 0.042 13.6 0.1 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CAR29609.1 - 8.9e-06 25.7 0.0 0.25 11.3 0.0 2.9 3 0 0 3 3 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CAR29609.1 - 1.5e-05 24.8 0.0 0.081 12.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CAR29609.1 - 1.8e-05 25.3 0.0 0.057 14.0 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.14 CAR29609.1 - 2.6e-05 24.4 0.0 0.0012 19.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CAR29609.1 - 3.3e-05 24.2 0.0 0.087 13.2 0.0 2.9 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 CAR29609.1 - 3.5e-05 23.6 0.0 0.23 11.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 CAR29609.1 - 0.0001 22.8 0.3 0.03 14.9 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_11 PF13086.6 CAR29609.1 - 0.00011 22.2 0.1 0.33 10.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain CDC48_N PF02359.18 CAR29609.1 - 0.00012 22.2 0.0 0.00053 20.1 0.0 2.2 2 1 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_30 PF13604.6 CAR29609.1 - 0.0003 20.6 0.0 0.54 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CAR29609.1 - 0.00034 20.2 0.0 0.045 13.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 CAR29609.1 - 0.00034 20.6 2.7 0.76 9.7 0.0 3.9 4 1 0 5 5 4 1 NACHT domain NB-ARC PF00931.22 CAR29609.1 - 0.00041 19.6 0.0 0.61 9.2 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.26 CAR29609.1 - 0.00051 19.8 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.16 CAR29609.1 - 0.00056 19.4 0.0 0.43 10.0 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.15 CAR29609.1 - 0.00066 19.7 0.0 0.46 10.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 CAR29609.1 - 0.00074 19.6 0.0 1.4 9.0 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CAR29609.1 - 0.0018 18.6 0.0 0.71 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 CAR29609.1 - 0.0019 18.1 0.0 0.18 11.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CAR29609.1 - 0.0039 16.6 0.1 2.3 7.6 0.1 3.2 2 1 0 2 2 2 1 Bacterial TniB protein AAA_25 PF13481.6 CAR29609.1 - 0.0039 16.8 0.4 4.4 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain Bac_DnaA PF00308.18 CAR29609.1 - 0.0048 16.8 0.0 2.2 8.0 0.0 2.9 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_17 PF13207.6 CAR29609.1 - 0.0052 17.2 0.1 2.8 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CAR29609.1 - 0.0061 16.5 0.1 2.3 8.1 0.1 2.9 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 CAR29609.1 - 0.0099 16.1 0.0 4.8 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CAR29609.1 - 0.012 14.9 0.0 0.93 8.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 CAR29609.1 - 0.015 14.6 2.7 0.32 10.3 0.1 3.0 4 0 0 4 4 3 0 KaiC Zeta_toxin PF06414.12 CAR29609.1 - 0.016 14.5 0.0 0.76 9.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 CAR29609.1 - 0.063 12.4 0.0 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 CAR29609.1 - 0.064 13.7 2.9 8.1 6.9 1.2 2.5 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 CAR29609.1 - 0.076 12.2 0.5 14 4.7 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 CAR29609.1 - 0.076 12.9 0.2 21 4.9 0.3 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 CAR29609.1 - 0.081 12.0 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.6 CAR29609.1 - 0.087 12.6 0.2 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 CAR29609.1 - 0.093 12.9 0.0 28 4.8 0.0 2.9 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 CAR29609.1 - 0.093 12.6 0.1 4.7 7.1 0.0 2.6 2 0 0 2 2 2 0 NTPase Vps4_C PF09336.10 CAR29609.1 - 0.1 12.6 0.1 0.36 10.8 0.0 2.0 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain cobW PF02492.19 CAR29609.1 - 0.19 11.3 1.1 15 5.1 0.0 3.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Yos9_DD PF17880.1 CAR29611.1 - 1.7e-48 163.9 0.0 5.6e-47 159.0 0.0 2.7 3 0 0 3 3 3 1 Yos9 dimerzation domain PRKCSH PF07915.13 CAR29611.1 - 9.8e-10 39.3 0.5 9.8e-10 39.3 0.5 3.1 4 0 0 4 4 4 1 Glucosidase II beta subunit-like protein Bromodomain PF00439.25 CAR29612.1 - 2.6e-15 56.2 2.7 2.6e-15 56.2 0.5 2.2 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.13 CAR29612.1 - 0.0002 21.3 0.0 0.012 15.6 0.0 2.5 1 1 1 2 2 2 1 Bromodomain associated Bromo_TP_like PF17027.5 CAR29612.1 - 0.26 11.4 4.2 0.094 12.9 0.3 2.4 2 0 0 2 2 2 0 Histone-fold protein UQ_con PF00179.26 CAR29613.1 - 4.8e-52 175.3 0.0 5.4e-52 175.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAR29613.1 - 0.0025 18.1 0.0 0.0037 17.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CAR29613.1 - 0.0051 16.5 0.0 0.0063 16.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CAR29613.1 - 0.027 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain CBF PF03914.17 CAR29614.1 - 1.6e-45 155.2 0.7 1.6e-45 155.2 0.7 3.3 3 0 0 3 3 3 1 CBF/Mak21 family Cnd1 PF12717.7 CAR29614.1 - 1.1 9.3 5.4 0.2 11.7 0.2 2.4 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TEA PF01285.18 CAR29615.1 - 2.3e-23 82.0 0.3 4e-23 81.2 0.3 1.4 1 0 0 1 1 1 1 TEA/ATTS domain MCM6_C PF18263.1 CAR29615.1 - 0.039 14.2 0.1 0.08 13.2 0.1 1.4 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain FTHFS PF01268.19 CAR29616.1 - 1.4e-249 829.0 0.2 1.8e-249 828.6 0.2 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CAR29616.1 - 1.6e-67 225.8 0.1 1.6e-67 225.8 0.1 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CAR29616.1 - 1.7e-35 121.8 0.1 4e-35 120.6 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.21 CAR29616.1 - 0.045 13.8 0.3 2 8.5 0.3 2.6 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PBP-Tp47_a PF14889.6 CAR29616.1 - 0.096 12.3 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a Ribosomal_L19e PF01280.20 CAR29617.1 - 9.4e-58 194.4 10.2 9.4e-58 194.4 10.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e DUF2423 PF10338.9 CAR29618.1 - 1.8e-15 56.9 9.6 1.8e-15 56.9 9.6 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2423) OmpH PF03938.14 CAR29618.1 - 1.9 8.8 11.8 2.4 8.5 11.8 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zinc_ribbon_15 PF17032.5 CAR29620.1 - 5.8e-05 23.8 0.0 8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 zinc-ribbon family Prim_Zn_Ribbon PF08273.12 CAR29620.1 - 0.001 19.3 0.3 0.024 14.9 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding domain of primase-helicase Zn_Tnp_IS1595 PF12760.7 CAR29620.1 - 0.0017 18.3 2.5 0.016 15.1 0.3 2.2 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-LITAF-like PF10601.9 CAR29620.1 - 0.04 14.2 1.1 0.04 14.2 1.1 2.4 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain Rep_1 PF01446.17 CAR29620.1 - 0.098 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Replication protein DpnI PF06044.12 CAR29620.1 - 0.35 10.5 1.5 1.2 8.7 0.3 2.0 2 0 0 2 2 2 0 Dam-replacing family zf-ribbon_3 PF13248.6 CAR29620.1 - 0.9 9.0 6.3 5 6.7 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain Mito_carr PF00153.27 CAR29621.1 - 1.1e-68 227.2 5.1 1.1e-23 83.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CAR29621.1 - 0.014 14.6 0.1 0.25 10.5 0.1 2.1 2 0 0 2 2 2 0 Fuseless Msap1 PF17077.5 CAR29622.1 - 7.3e-30 104.3 22.3 7.3e-30 104.3 22.3 3.0 1 1 1 2 2 2 1 Mitotic spindle associated protein SHE1 KH_1 PF00013.29 CAR29623.1 - 6.2e-26 90.0 6.9 6.1e-10 38.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CAR29623.1 - 7.3e-09 35.3 6.8 0.00059 19.6 0.1 3.6 4 0 0 4 4 4 3 KH domain KH_4 PF13083.6 CAR29623.1 - 5.8e-05 22.9 3.5 1.2 9.1 0.1 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 CAR29623.1 - 0.00036 20.6 4.8 0.79 9.9 0.3 3.5 3 0 0 3 3 3 2 NusA-like KH domain GTP_cyclohydro2 PF00925.20 CAR29624.1 - 5.7e-55 185.3 0.0 1e-54 184.5 0.0 1.4 1 1 0 1 1 1 1 GTP cyclohydrolase II CLASP_N PF12348.8 CAR29626.1 - 1.3e-68 230.9 11.8 1.8e-68 230.5 5.7 3.2 3 0 0 3 3 3 1 CLASP N terminal ParcG PF10274.9 CAR29626.1 - 0.79 9.8 4.6 0.25 11.5 0.2 2.4 3 0 0 3 3 3 0 Parkin co-regulated protein Pol_alpha_B_N PF08418.10 CAR29627.1 - 5.3e-62 210.0 1.5 8.7e-62 209.3 1.5 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 CAR29627.1 - 1.1e-42 145.8 0.4 1.6e-42 145.3 0.4 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CAR29627.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain ACP_PD PF04336.12 CAR29627.1 - 0.15 12.5 0.1 19 5.8 0.2 2.9 2 0 0 2 2 2 0 Acyl carrier protein phosphodiesterase Anoctamin PF04547.12 CAR29628.1 - 2.8e-36 125.3 14.7 5.5e-35 121.1 14.7 2.0 1 1 0 1 1 1 1 Calcium-activated chloride channel EamA PF00892.20 CAR29630.1 - 6.2e-26 91.2 30.3 1.7e-14 54.2 7.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 CAR29630.1 - 0.00072 19.2 8.4 0.0011 18.5 8.4 1.3 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 CAR29630.1 - 0.00097 18.2 1.2 0.0015 17.6 1.2 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 CAR29630.1 - 0.019 14.3 10.8 0.039 13.3 0.9 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Mg_trans_NIPA PF05653.14 CAR29630.1 - 1.6 7.8 11.1 0.12 11.4 4.8 2.3 3 1 0 3 3 3 0 Magnesium transporter NIPA GFD1 PF17331.2 CAR29631.1 - 5.4e-08 32.8 12.2 1.6e-07 31.3 12.2 1.9 1 0 0 1 1 1 1 GFD1 mRNA transport factor COX7a PF02238.15 CAR29633.1 - 6.1e-23 81.0 0.3 6.8e-23 80.8 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII zf-C3HC4_3 PF13920.6 CAR29634.1 - 7.1e-10 38.6 13.5 2.1e-08 33.9 5.2 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR29634.1 - 1.2e-08 34.6 9.0 1.2e-08 34.6 9.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CAR29634.1 - 2.5e-08 33.9 11.0 2.5e-08 33.9 11.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CAR29634.1 - 5.6e-08 32.7 6.1 5.6e-08 32.7 6.1 2.0 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CAR29634.1 - 3.6e-07 30.4 9.1 3.6e-07 30.4 9.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 CAR29634.1 - 5.3e-07 29.4 9.1 5.3e-07 29.4 9.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CAR29634.1 - 1.8e-05 24.6 7.4 1.8e-05 24.6 7.4 2.5 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CAR29634.1 - 0.00012 21.8 15.7 0.00043 20.1 7.5 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CAR29634.1 - 0.0017 18.6 6.3 0.0017 18.6 6.3 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAR29634.1 - 0.0034 17.4 2.6 0.0034 17.4 2.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 CAR29634.1 - 0.0085 15.9 3.6 0.0085 15.9 3.6 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CAR29634.1 - 0.016 15.0 13.0 0.49 10.2 6.8 3.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain HypA PF01155.19 CAR29634.1 - 0.017 15.1 6.0 0.34 10.9 0.2 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-UDP PF14569.6 CAR29634.1 - 0.034 14.3 12.6 0.19 11.9 1.2 3.3 2 1 0 2 2 2 0 Zinc-binding RING-finger DZR PF12773.7 CAR29634.1 - 0.14 12.2 11.4 0.87 9.7 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-C4_Topoisom PF01396.19 CAR29634.1 - 0.14 12.0 1.6 1.8 8.4 0.1 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Zn-ribbon_8 PF09723.10 CAR29634.1 - 0.79 9.9 7.7 1 9.6 0.5 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 CAR29634.1 - 3.3 7.5 13.5 0.24 11.2 1.6 3.5 3 1 1 4 4 3 0 zinc-ribbon domain zf-MIZ PF02891.20 CAR29634.1 - 4.2 7.2 11.7 0.81 9.5 7.5 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger RNHCP PF12647.7 CAR29634.1 - 4.3 7.4 8.1 6.2 6.9 2.0 2.6 2 0 0 2 2 2 0 RNHCP domain TF_Zn_Ribbon PF08271.12 CAR29634.1 - 5.2 6.7 14.7 1.8 8.1 1.9 4.0 2 1 1 3 3 3 0 TFIIB zinc-binding zinc_ribbon_4 PF13717.6 CAR29634.1 - 5.3 7.1 6.7 1.1e+02 2.8 0.5 3.6 3 0 0 3 3 3 0 zinc-ribbon domain FANCL_C PF11793.8 CAR29634.1 - 7.3 6.9 9.6 73 3.6 0.0 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain TPR_8 PF13181.6 CAR29635.1 - 0.032 14.4 1.4 6.3 7.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAR29635.1 - 0.059 14.2 0.0 7.9 7.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.7 CAR29636.1 - 0.075 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 F-box-like DUF2428 PF10350.9 CAR29637.1 - 9.5e-44 149.7 0.1 2.5e-43 148.3 0.1 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CAR29637.1 - 4.5e-09 35.8 0.3 0.049 13.9 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CAR29637.1 - 2.2e-06 28.0 0.0 0.015 15.7 0.0 3.9 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 CAR29637.1 - 0.0022 18.5 0.0 0.025 15.1 0.1 2.7 2 0 0 2 2 2 1 HEAT-like repeat MMS19_N PF14500.6 CAR29637.1 - 0.0066 16.1 0.8 0.058 13.0 0.1 2.9 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.7 CAR29637.1 - 0.13 12.3 6.4 0.12 12.4 0.7 3.6 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 eIF-1a PF01176.19 CAR29638.1 - 1.7e-20 72.6 0.1 2.3e-20 72.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Glyco_transf_20 PF00982.21 CAR29639.1 - 4.6e-167 556.5 0.3 6.5e-167 556.0 0.3 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CAR29639.1 - 1.7e-38 132.1 0.0 3.7e-38 131.0 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Trans_coact PF16805.5 CAR29639.1 - 0.087 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Phage late-transcription coactivator TatD_DNase PF01026.21 CAR29640.1 - 3.2e-38 131.6 0.1 4.1e-38 131.2 0.1 1.2 1 0 0 1 1 1 1 TatD related DNase SAP30_Sin3_bdg PF13867.6 CAR29641.1 - 3.4e-10 40.1 0.1 5.9e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Cue1_U7BR PF18499.1 CAR29642.1 - 3.9e-26 90.8 4.0 5.7e-26 90.3 4.0 1.3 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 CUE PF02845.16 CAR29642.1 - 9.8e-11 41.1 0.0 1.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain WD40 PF00400.32 CAR29643.1 - 5.8e-20 71.3 2.1 0.00021 22.0 0.0 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29643.1 - 3.7e-14 52.8 0.3 7.1e-09 35.9 0.1 3.8 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CAR29643.1 - 0.00013 21.9 0.2 0.024 14.5 0.0 3.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR29643.1 - 0.002 17.1 0.1 2.5 7.0 0.0 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 CAR29643.1 - 0.0034 16.5 0.4 0.4 9.7 0.0 2.4 2 1 0 2 2 2 2 Coatomer WD associated region PD40 PF07676.12 CAR29643.1 - 0.16 11.9 0.7 3.8 7.6 0.1 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat HAD_SAK_1 PF10307.9 CAR29644.1 - 3.7e-52 177.1 0.0 5.9e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins RSN1_7TM PF02714.15 CAR29645.1 - 6e-80 268.5 24.0 6e-80 268.5 24.0 2.0 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CAR29645.1 - 4.9e-42 143.3 4.8 4.9e-42 143.3 4.8 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CAR29645.1 - 5.7e-28 98.3 0.2 1e-27 97.5 0.2 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CAR29645.1 - 3.2e-23 81.7 0.0 8.8e-23 80.3 0.0 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Pyrophosphatase PF00719.19 CAR29646.1 - 8.7e-55 184.9 0.1 1.1e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Thioredoxin_10 PF17991.1 CAR29646.1 - 0.055 14.0 0.0 0.91 10.1 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin like C-terminal domain Nup188 PF10487.9 CAR29647.1 - 0 1073.4 25.1 0 1072.8 25.1 1.2 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 CAR29647.1 - 8.2e-19 67.7 7.3 1.7e-18 66.6 7.3 1.5 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain RRM_1 PF00076.22 CAR29648.1 - 2.1e-37 126.8 0.5 6e-13 48.4 0.1 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CAR29648.1 - 1.1e-35 121.4 0.8 1.5e-27 95.3 0.7 4.1 4 0 0 4 4 4 3 Occluded RNA-recognition motif Lsm_interact PF05391.11 CAR29648.1 - 3.4e-08 32.7 1.1 3.4e-08 32.7 1.1 1.8 2 0 0 2 2 2 1 Lsm interaction motif RRM_5 PF13893.6 CAR29648.1 - 0.00011 21.8 0.2 0.022 14.4 0.0 3.3 1 1 2 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CAR29648.1 - 0.0053 16.7 0.1 3.7 7.6 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 CAR29648.1 - 0.008 16.2 2.0 6 6.9 0.2 3.5 3 0 0 3 3 3 2 DbpA RNA binding domain ACT_3 PF10000.9 CAR29648.1 - 0.018 14.9 0.1 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 ACT domain RL PF17797.1 CAR29648.1 - 0.025 14.5 0.1 0.073 13.0 0.1 1.7 1 0 0 1 1 1 0 RL domain PHM7_cyt PF14703.6 CAR29648.1 - 0.052 13.8 2.7 1.8 8.8 2.0 3.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter G-patch PF01585.23 CAR29649.1 - 0.005 16.7 1.8 0.005 16.7 1.8 2.6 2 0 0 2 2 2 1 G-patch domain DDHD PF02862.17 CAR29649.1 - 0.091 12.9 5.5 0.087 13.0 5.5 1.2 1 0 0 1 1 1 0 DDHD domain AAA_21 PF13304.6 CAR29649.1 - 0.28 10.9 2.7 0.36 10.6 2.7 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RR_TM4-6 PF06459.12 CAR29649.1 - 0.41 10.4 23.3 0.49 10.2 23.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CAR29649.1 - 0.87 7.8 20.1 1 7.6 20.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 CAR29649.1 - 1.3 9.1 5.4 1.2 9.1 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EOS1 PF12326.8 CAR29649.1 - 5.2 7.0 7.4 7 6.5 7.4 1.3 1 0 0 1 1 1 0 N-glycosylation protein RNA_polI_A34 PF08208.11 CAR29649.1 - 6.2 6.9 42.0 9.1 6.3 42.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PXA PF02194.15 CAR29650.1 - 6.5e-31 107.7 0.9 6.5e-31 107.7 0.9 3.5 2 1 1 3 3 3 1 PXA domain Nexin_C PF08628.12 CAR29650.1 - 2.4e-23 82.9 0.3 1.2e-22 80.6 0.1 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 CAR29650.1 - 8.1e-15 54.8 3.8 8.1e-15 54.8 3.8 2.7 3 0 0 3 3 3 1 PX domain RGS PF00615.19 CAR29650.1 - 3.4 7.9 15.6 0.018 15.3 3.1 3.7 4 1 0 4 4 4 0 Regulator of G protein signaling domain RRN9 PF10680.9 CAR29651.1 - 1.7e-16 60.2 0.8 4.4e-16 58.9 0.8 1.8 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor SRP19 PF01922.17 CAR29652.1 - 2e-28 99.2 0.0 3.9e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Pribosyltran PF00156.27 CAR29653.1 - 7.8e-17 61.2 0.1 1.1e-16 60.7 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain zf-C3HC PF07967.13 CAR29654.1 - 7.4e-09 35.7 11.7 2.4e-06 27.6 3.3 2.9 2 1 1 3 3 3 2 C3HC zinc finger-like BIR PF00653.21 CAR29654.1 - 0.32 11.7 9.0 0.35 11.5 1.0 2.6 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain Cyt-b5 PF00173.28 CAR29655.1 - 9.2e-21 73.8 0.2 9.2e-21 73.8 0.2 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 CAR29655.1 - 1.1e-14 54.9 13.7 1.1e-14 54.9 13.7 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 CAR29655.1 - 0.031 14.5 0.3 0.064 13.5 0.3 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region ATP-synt_I PF03899.15 CAR29655.1 - 0.24 11.8 2.0 0.75 10.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase I chain DUF1892 PF08987.10 CAR29656.1 - 3.1e-48 162.5 2.5 5.3e-48 161.8 2.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1892) Zds_C PF08632.10 CAR29657.1 - 2.6e-29 100.7 1.9 4.4e-29 100.0 1.9 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term PvlArgDC PF01862.16 CAR29657.1 - 1.8 8.4 4.6 9.9 5.9 4.6 2.3 1 0 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) CPBP PF02517.16 CAR29658.1 - 1.9e-16 60.2 5.2 1.9e-16 60.2 5.2 2.2 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Ubie_methyltran PF01209.18 CAR29659.1 - 7.9e-99 329.7 0.2 9.9e-99 329.4 0.2 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CAR29659.1 - 8.7e-12 45.6 0.0 1.6e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR29659.1 - 3.6e-10 40.3 0.0 7.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR29659.1 - 2.4e-09 37.2 0.1 4e-09 36.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR29659.1 - 2.7e-09 37.6 0.1 5e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR29659.1 - 0.00012 22.0 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 CAR29659.1 - 0.032 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Bul1_N PF04425.12 CAR29660.1 - 9.9e-164 545.4 1.8 1.6e-163 544.7 0.7 1.8 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.12 CAR29660.1 - 1.9e-105 352.2 5.6 3.7e-105 351.2 5.6 1.5 1 0 0 1 1 1 1 Bul1 C terminus Lzipper-MIP1 PF14389.6 CAR29660.1 - 0.018 15.3 0.2 0.055 13.8 0.2 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 CTK3_C PF12350.8 CAR29661.1 - 2.3e-20 72.5 0.3 4.4e-20 71.6 0.3 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 CAR29661.1 - 4.7e-06 26.6 0.4 7.8e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 FYDLN_acid PF09538.10 CAR29662.1 - 0.71 10.6 4.9 1.5 9.5 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) TPPII_N PF12583.8 CAR29662.1 - 8.6 6.9 27.3 0.52 10.9 21.5 1.8 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal ubiquitin PF00240.23 CAR29663.1 - 1.4e-22 79.2 0.4 2e-22 78.7 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CAR29663.1 - 1e-09 38.0 0.1 1.7e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CAR29663.1 - 3.9e-06 27.2 0.2 7.9e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain UBA PF00627.31 CAR29663.1 - 4.9e-06 26.3 0.6 1.3e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain TBK1_ULD PF18396.1 CAR29663.1 - 0.00018 21.4 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CAR29663.1 - 0.00039 20.5 0.0 0.00089 19.3 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 CAR29663.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair GerD PF17898.1 CAR29663.1 - 0.073 13.0 5.1 0.15 12.0 5.1 1.4 1 0 0 1 1 1 0 Spore germination GerD central core domain DUF2407 PF10302.9 CAR29663.1 - 0.14 12.7 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain UN_NPL4 PF11543.8 CAR29663.1 - 0.21 12.1 0.2 0.34 11.4 0.2 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 TAF8_C PF10406.9 CAR29664.1 - 5.7e-18 65.2 1.7 5.7e-18 65.2 1.7 3.1 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term CENP-T_C PF15511.6 CAR29664.1 - 0.0046 17.1 2.3 0.0057 16.8 0.3 2.3 2 1 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold DUF3247 PF11607.8 CAR29664.1 - 0.86 9.9 4.6 0.21 11.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3247) NIF PF03031.18 CAR29665.1 - 9.4e-23 80.7 0.2 1.3e-21 77.0 0.0 2.3 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 CAR29665.1 - 1.9e-10 41.0 0.0 4.9e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CAR29665.1 - 4.2e-05 23.4 0.1 9.2e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 CAR29665.1 - 0.0032 17.7 0.1 0.01 16.1 0.1 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 CAR29665.1 - 0.025 15.0 0.0 0.075 13.5 0.0 1.9 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain DUF3396 PF11876.8 CAR29665.1 - 0.12 11.9 0.0 0.34 10.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3396) NdhM PF10664.9 CAR29665.1 - 0.17 12.2 1.3 0.58 10.4 0.2 2.5 2 1 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M PGM_PMM_I PF02878.16 CAR29666.1 - 2.7e-38 130.8 0.0 5.8e-38 129.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CAR29666.1 - 3.4e-22 79.0 0.0 1.1e-21 77.4 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CAR29666.1 - 3.4e-15 56.2 0.0 7.2e-14 52.0 0.0 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CAR29666.1 - 7.2e-06 26.1 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain S-methyl_trans PF02574.16 CAR29667.1 - 1.1e-57 196.0 0.0 1.2e-57 195.8 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.25 CAR29667.1 - 0.011 15.3 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Anp1 PF03452.14 CAR29668.1 - 1.1e-117 392.2 0.0 1.5e-117 391.7 0.0 1.2 1 0 0 1 1 1 1 Anp1 Nab6_mRNP_bdg PF10567.9 CAR29669.1 - 4.5e-127 423.9 6.2 4.5e-127 423.9 6.2 4.1 5 0 0 5 5 5 1 RNA-recognition motif RRM PF10378.9 CAR29669.1 - 2e-18 65.8 7.4 2e-18 65.8 7.4 4.5 3 2 1 4 4 4 1 Putative RRM domain RRM_1 PF00076.22 CAR29669.1 - 6.2e-07 29.1 1.0 0.021 14.6 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 CAR29669.1 - 0.00047 19.8 24.9 0.00047 19.8 24.9 5.2 4 1 0 4 4 4 1 Spt20 family Fungal_trans PF04082.18 CAR29670.1 - 1e-40 139.5 0.2 2e-40 138.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR29670.1 - 1.8e-10 40.7 12.8 3e-10 40.1 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 CAR29670.1 - 0.055 13.4 1.1 0.16 12.0 1.1 1.8 1 0 0 1 1 1 0 AT hook motif PIG-L PF02585.17 CAR29671.1 - 2.9e-21 76.5 0.1 3.9e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.7 CAR29672.1 - 1.9e-26 92.2 0.0 9.2e-26 90.0 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial ATPase expression XH PF03469.14 CAR29672.1 - 0.014 15.3 0.3 0.014 15.3 0.3 1.8 2 0 0 2 2 2 0 XH domain Rit1_C PF17184.4 CAR29673.1 - 1.2e-98 329.9 0.0 4e-98 328.2 0.0 1.7 2 0 0 2 2 2 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 CAR29673.1 - 4.3e-28 97.8 0.8 2.1e-27 95.6 0.6 2.2 2 0 0 2 2 2 1 Rit1 DUSP-like domain Ribonuc_red_sm PF00268.21 CAR29674.1 - 3.4e-118 394.2 1.2 4.3e-118 393.8 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain U3_snoRNA_assoc PF08297.11 CAR29675.1 - 2e-13 50.8 6.6 2e-13 50.8 6.6 2.2 2 0 0 2 2 2 2 U3 snoRNA associated Ndc1_Nup PF09531.10 CAR29675.1 - 3.1 6.4 5.2 3.2 6.3 5.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 CAR29676.1 - 2.6e-22 79.5 17.2 7e-15 55.1 5.4 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter F-box-like PF12937.7 CAR29677.1 - 1.3e-08 34.5 0.2 3.1e-08 33.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like TPR_14 PF13428.6 CAR29677.1 - 9.5e-06 26.0 0.3 0.18 12.7 0.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CAR29677.1 - 5.5e-05 22.9 2.0 0.36 11.0 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR29677.1 - 0.00022 21.5 1.8 0.064 13.5 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CAR29677.1 - 0.0006 19.7 5.1 0.047 13.8 0.8 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAR29677.1 - 0.0011 18.7 4.3 0.054 13.3 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR29677.1 - 0.0013 18.8 2.1 0.1 12.7 0.1 2.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat LRR_6 PF13516.6 CAR29677.1 - 0.0026 17.7 2.2 2.9 8.2 0.1 4.1 4 0 0 4 4 4 2 Leucine Rich repeat F-box PF00646.33 CAR29677.1 - 0.1 12.5 1.7 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 F-box domain TPR_16 PF13432.6 CAR29677.1 - 0.2 12.4 1.2 7.7 7.3 0.1 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR29677.1 - 0.44 10.8 2.2 21 5.4 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CAR29677.1 - 1.3 9.8 4.8 1.6 9.5 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3336 PF11815.8 CAR29678.1 - 1.1e-30 106.1 5.3 2e-30 105.3 5.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CAR29678.1 - 2e-25 90.2 0.0 4.2e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase LIM PF00412.22 CAR29679.1 - 1.4e-15 57.3 20.8 2e-08 34.3 7.3 2.4 2 0 0 2 2 2 2 LIM domain Whi5 PF08528.11 CAR29680.1 - 1.4e-09 37.3 0.2 2.8e-09 36.4 0.2 1.5 1 0 0 1 1 1 1 Whi5 like MarB PF13999.6 CAR29680.1 - 0.0086 15.9 0.5 0.026 14.4 0.5 1.9 1 0 0 1 1 1 1 MarB protein Abhydrolase_6 PF12697.7 CAR29681.1 - 5.3e-14 53.4 0.0 7.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CAR29681.1 - 2.3e-05 23.8 0.0 3.7e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CAR29681.1 - 0.00021 20.8 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 CAR29681.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 CAR29681.1 - 0.095 12.3 0.3 0.63 9.6 0.3 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Phage_cap_E PF03864.15 CAR29681.1 - 0.2 10.8 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 Phage major capsid protein E SRP40_C PF05022.12 CAR29682.1 - 1.7e-22 80.0 2.8 1.7e-22 80.0 2.8 4.4 5 1 0 5 5 5 1 SRP40, C-terminal domain ERCC3_RAD25_C PF16203.5 CAR29683.1 - 2.1e-123 410.3 1.0 2.1e-123 410.3 1.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CAR29683.1 - 9.1e-35 119.6 0.1 2.1e-34 118.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR29683.1 - 1.1e-15 58.0 0.0 2.9e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CAR29683.1 - 5.6e-11 42.8 2.3 7.7e-11 42.3 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CAR29683.1 - 5.7e-09 35.2 0.1 8.3e-09 34.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CAR29683.1 - 7.1e-05 22.6 0.0 0.00019 21.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Cas_Csm6 PF09659.10 CAR29683.1 - 0.045 12.5 0.9 1.1 8.0 0.4 2.2 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csm6) Med3 PF11593.8 CAR29683.1 - 0.51 9.5 10.6 1.3 8.1 7.1 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Ndc80_HEC PF03801.13 CAR29684.1 - 1.9e-49 167.2 0.4 1.9e-49 167.2 0.4 1.9 2 0 0 2 2 2 1 HEC/Ndc80p family DUF5595 PF18077.1 CAR29684.1 - 5.4e-12 45.6 4.5 5.4e-12 45.6 4.5 4.8 6 0 0 6 6 6 2 Domain of unknown function (DUF5595) DUF4639 PF15479.6 CAR29684.1 - 1.4 7.8 5.7 0.13 11.2 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4639) ApoO PF09769.9 CAR29684.1 - 1.5 8.8 6.3 10 6.1 1.2 3.2 2 1 1 3 3 3 0 Apolipoprotein O FTR1 PF03239.14 CAR29685.1 - 8.2e-95 317.5 7.7 9.8e-95 317.2 7.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family FAD_binding_4 PF01565.23 CAR29685.1 - 0.028 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DUF2070 PF09843.9 CAR29685.1 - 9.4 4.4 6.6 39 2.4 6.6 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) LSM PF01423.22 CAR29686.1 - 2.4e-16 59.2 0.0 2.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CAR29686.1 - 0.045 13.9 0.1 0.054 13.6 0.1 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.17 CAR29686.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.4 1 1 0 1 1 1 0 Biotin protein ligase C terminal domain Hfq PF17209.3 CAR29686.1 - 0.14 11.8 0.1 0.24 11.1 0.1 1.4 1 0 0 1 1 1 0 Hfq protein PAP2_3 PF14378.6 CAR29687.1 - 1.4e-12 47.7 23.3 6e-11 42.4 6.4 2.8 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 CAR29687.1 - 1.4e-07 31.3 14.0 5.3e-06 26.2 3.0 3.1 3 0 0 3 3 3 2 PAP2 superfamily PalH PF08733.10 CAR29687.1 - 0.39 9.7 8.8 0.9 8.5 8.8 1.5 1 0 0 1 1 1 0 PalH/RIM21 Glyco_transf_20 PF00982.21 CAR29689.1 - 2.4e-143 478.3 0.0 3.1e-143 477.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CAR29689.1 - 3.6e-80 268.5 0.0 5.4e-80 267.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 CAR29689.1 - 0.0091 15.5 0.0 0.028 14.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Cohesin_load PF10345.9 CAR29690.1 - 2.7e-89 300.3 24.3 3.3e-89 300.0 24.3 1.0 1 0 0 1 1 1 1 Cohesin loading factor TBP PF00352.21 CAR29691.1 - 2.3e-68 226.1 0.1 6.6e-33 112.5 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CAR29691.1 - 1.9e-05 24.7 0.1 0.25 11.5 0.0 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 CAR29691.1 - 0.035 13.9 0.2 0.26 11.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Nas2_N PF18265.1 CAR29692.1 - 0.4 10.6 5.2 0.71 9.8 0.0 3.3 2 1 0 3 3 3 0 Nas2 N_terminal domain UPF0242 PF06785.11 CAR29692.1 - 1.2 9.2 17.1 0.84 9.7 8.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 CAR29692.1 - 2.6 6.9 7.6 3.6 6.4 7.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Metallophos PF00149.28 CAR29693.1 - 4e-39 135.2 0.1 5e-39 134.9 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CAR29693.1 - 0.018 15.2 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain 8TM_micro PF17028.5 CAR29693.1 - 0.065 12.9 0.1 0.083 12.6 0.1 1.2 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain Rad51 PF08423.11 CAR29694.1 - 8.9e-05 21.9 0.0 0.0011 18.2 0.0 2.4 2 0 0 2 2 2 1 Rad51 DUF2075 PF09848.9 CAR29694.1 - 0.0001 21.7 0.1 0.00018 20.8 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 CAR29694.1 - 0.0045 16.4 0.0 0.009 15.4 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.6 CAR29694.1 - 0.0081 16.6 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RecA PF00154.21 CAR29694.1 - 0.05 13.1 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AA_permease PF00324.21 CAR29696.1 - 5.6e-46 157.1 34.4 5.6e-46 157.1 34.4 1.5 2 0 0 2 2 2 1 Amino acid permease SLC12 PF03522.15 CAR29696.1 - 6.6e-17 61.6 4.0 3.7e-10 39.4 0.0 3.4 2 1 1 3 3 3 3 Solute carrier family 12 OGFr_N PF04664.13 CAR29696.1 - 0.034 13.7 0.1 6.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Opioid growth factor receptor (OGFr) conserved region Pox_MCEL PF03291.16 CAR29697.1 - 2.7e-102 342.3 0.0 3.6e-102 341.9 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CAR29697.1 - 2.6e-11 44.1 0.0 4.9e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR29697.1 - 5.8e-10 39.8 0.0 1.7e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CAR29697.1 - 5e-08 33.5 0.0 1.1e-07 32.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR29697.1 - 2.1e-07 30.9 0.0 4.7e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR29697.1 - 1.6e-05 24.8 0.0 3.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CAR29697.1 - 0.027 13.9 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase NNMT_PNMT_TEMT PF01234.17 CAR29697.1 - 0.068 12.4 0.0 0.25 10.5 0.0 1.9 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family CMAS PF02353.20 CAR29697.1 - 0.087 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 CAR29697.1 - 0.099 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MetW PF07021.12 CAR29697.1 - 0.14 11.7 0.0 0.45 10.1 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Use1 PF09753.9 CAR29697.1 - 1.7 8.3 10.2 2.2 7.9 10.2 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 DEAD PF00270.29 CAR29698.1 - 9.6e-46 155.7 0.1 2.6e-45 154.3 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR29698.1 - 1.8e-21 76.6 0.1 1.2e-20 73.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR29698.1 - 5.3e-09 36.3 0.0 5.3e-09 36.3 0.0 3.6 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAR29698.1 - 0.0027 18.0 1.0 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arrestin_C PF02752.22 CAR29701.1 - 1.2e-12 48.4 0.0 3.5e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CAR29701.1 - 8e-06 26.0 0.0 0.00099 19.2 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Exo70 PF03081.15 CAR29702.1 - 1e-84 284.8 1.2 1e-84 284.8 1.2 2.1 2 1 0 2 2 2 1 Exo70 exocyst complex subunit Rx_N PF18052.1 CAR29702.1 - 0.029 14.7 0.0 0.095 13.0 0.0 1.9 1 0 0 1 1 1 0 Rx N-terminal domain DUF5344 PF17279.2 CAR29702.1 - 1.9 9.1 4.3 11 6.7 0.0 4.0 4 1 0 4 4 4 0 Family of unknown function (DUF5344) RNA_lig_T4_1 PF09511.10 CAR29703.1 - 5.6e-80 268.3 0.0 1.1e-79 267.3 0.0 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 CAR29703.1 - 6.6e-73 244.3 0.1 1.6e-72 243.1 0.1 1.7 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 CAR29703.1 - 9.2e-60 202.2 0.0 1.3e-59 201.7 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain ResIII PF04851.15 CAR29703.1 - 0.21 11.6 1.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit OTCace PF00185.24 CAR29704.1 - 1.6e-49 168.0 0.6 2.5e-49 167.3 0.6 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 CAR29704.1 - 1.3e-42 145.3 0.1 3e-42 144.1 0.1 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain NTR2 PF15458.6 CAR29705.1 - 1e-20 74.5 21.1 2.3e-18 66.8 9.3 2.2 1 1 1 2 2 2 2 Nineteen complex-related protein 2 KRAB PF01352.27 CAR29705.1 - 0.073 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 KRAB box Zn_clus PF00172.18 CAR29706.1 - 2e-11 43.8 11.3 3.4e-11 43.1 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_trans_assoc PF06512.13 CAR29706.1 - 0.057 13.7 3.0 0.16 12.2 3.0 1.8 1 0 0 1 1 1 0 Sodium ion transport-associated VF530 PF09905.9 CAR29706.1 - 0.11 12.6 0.1 3.8 7.8 0.0 2.5 2 0 0 2 2 2 0 DNA-binding protein VF530 Cwf_Cwc_15 PF04889.12 CAR29706.1 - 1.9 8.1 12.5 0.25 11.1 6.0 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BRCT PF00533.26 CAR29707.1 - 3.7e-14 52.9 8.8 7.1e-05 23.1 0.0 4.9 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CAR29707.1 - 1.3e-11 44.2 0.2 6.6e-06 26.0 0.0 3.7 4 0 0 4 4 4 2 twin BRCT domain BRCT_2 PF16589.5 CAR29707.1 - 5.7e-10 39.5 3.6 0.0015 18.9 0.2 3.6 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CAR29707.1 - 0.0075 16.3 0.0 0.23 11.6 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Perm-CXXC PF15629.6 CAR29707.1 - 0.011 16.0 2.9 0.03 14.6 2.9 1.7 1 0 0 1 1 1 0 Permuted single zf-CXXC unit RTT107_BRCT_5 PF16770.5 CAR29707.1 - 0.19 11.6 0.7 66 3.5 0.0 4.3 5 0 0 5 5 5 0 Regulator of Ty1 transposition protein 107 BRCT domain GWT1 PF06423.12 CAR29708.1 - 1.1e-38 132.7 0.3 1.1e-38 132.7 0.3 2.8 3 1 2 5 5 5 1 GWT1 DUF2214 PF09980.9 CAR29708.1 - 0.011 15.5 1.5 0.05 13.4 0.6 2.5 2 1 1 3 3 3 0 Predicted membrane protein (DUF2214) CrgA PF06781.12 CAR29708.1 - 0.4 10.8 2.7 0.57 10.3 0.0 2.5 3 0 0 3 3 3 0 Cell division protein CrgA Afaf PF15339.6 CAR29708.1 - 0.95 9.1 2.7 11 5.6 0.1 2.3 2 0 0 2 2 2 0 Acrosome formation-associated factor UvrD-helicase PF00580.21 CAR29709.1 - 2.1e-66 224.6 0.0 6.6e-66 223.0 0.0 1.9 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CAR29709.1 - 3.6e-43 148.3 0.0 2.9e-42 145.3 0.0 2.5 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CAR29709.1 - 8.4e-29 100.8 0.0 1.9e-28 99.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CAR29709.1 - 1.3e-09 37.7 0.0 0.00024 20.9 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 CAR29709.1 - 0.00021 21.2 0.0 0.00021 21.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CAR29709.1 - 0.00048 19.9 0.0 0.0092 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 CAR29709.1 - 0.0046 16.8 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 Helicase Ion_trans_2 PF07885.16 CAR29710.1 - 3.4e-26 91.0 24.6 2e-17 62.9 6.7 3.5 4 0 0 4 4 4 2 Ion channel DNA_pol_phi PF04931.13 CAR29710.1 - 0.025 12.7 3.8 0.045 11.9 3.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi Ion_trans PF00520.31 CAR29710.1 - 0.042 13.1 30.7 0.083 12.1 3.9 3.6 2 1 0 2 2 2 0 Ion transport protein PI3K_1B_p101 PF10486.9 CAR29710.1 - 0.64 7.7 2.3 0.84 7.3 2.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 CAR29710.1 - 0.76 9.0 6.4 1.6 8.0 6.4 1.4 1 0 0 1 1 1 0 NOA36 protein Na_H_Exchanger PF00999.21 CAR29711.1 - 6e-54 183.3 29.6 8e-54 182.9 29.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF4131 PF13567.6 CAR29711.1 - 0.18 11.4 1.8 7.4 6.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 CAR29712.1 - 1.3e-67 228.0 0.0 2.4e-67 227.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29712.1 - 5.6e-46 156.9 0.0 9.7e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR29712.1 - 3.7e-13 49.4 0.0 1.8e-09 37.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_2 PF07647.17 CAR29712.1 - 0.0035 17.4 0.1 0.0086 16.2 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 CAR29712.1 - 0.028 14.4 0.2 0.075 13.0 0.2 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Kdo PF06293.14 CAR29712.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR29712.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L21p PF00829.21 CAR29713.1 - 9e-12 45.2 0.2 1.1e-11 44.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein PTPLA PF04387.14 CAR29714.1 - 1.3e-43 148.6 8.4 2e-43 148.0 8.4 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA NPCC PF08058.11 CAR29714.1 - 0.034 14.2 1.7 2.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Nuclear pore complex component SAPS PF04499.15 CAR29715.1 - 1.5e-181 604.5 1.0 1.5e-181 604.5 1.0 3.5 3 1 0 3 3 3 2 SIT4 phosphatase-associated protein PhzC-PhzF PF02567.16 CAR29716.1 - 1.4e-63 215.0 0.0 1.6e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 CAR29716.1 - 8.4e-07 28.3 0.0 1.6e-06 27.4 0.0 1.4 2 0 0 2 2 2 1 Proline racemase Epimerase PF01370.21 CAR29717.1 - 2.4e-17 63.2 0.1 4.2e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR29717.1 - 1.2e-12 47.5 0.0 1.7e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CAR29717.1 - 6.8e-11 41.8 0.0 6.5e-05 22.2 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 CAR29717.1 - 9.7e-10 38.4 0.2 1.3e-08 34.6 0.2 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CAR29717.1 - 3.7e-08 33.5 0.0 7e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CAR29717.1 - 1.5e-06 27.8 0.3 2.6e-06 27.1 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CAR29717.1 - 1e-05 25.2 0.2 1.7e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 CAR29717.1 - 0.00014 21.5 0.1 0.024 14.2 0.1 2.4 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 CAR29717.1 - 0.001 19.0 0.1 0.0032 17.4 0.1 1.8 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 CAR29717.1 - 0.0022 18.0 0.0 0.0048 17.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 CAR29717.1 - 0.0088 15.2 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CAR29717.1 - 0.053 12.6 0.0 0.093 11.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 CAR29717.1 - 0.069 13.7 0.0 0.21 12.2 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 CAR29717.1 - 0.092 12.4 0.5 0.48 10.0 0.5 2.1 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.16 CAR29718.1 - 2.1e-30 105.8 23.3 3e-28 98.8 22.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR29718.1 - 0.00012 21.1 8.8 0.00012 21.1 8.8 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter Oxidored_FMN PF00724.20 CAR29719.1 - 3.8e-44 151.4 0.0 1.4e-43 149.5 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NMO PF03060.15 CAR29720.1 - 1.7e-72 244.7 0.0 2e-72 244.4 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CAR29720.1 - 4.5e-09 35.8 0.1 0.00068 18.7 0.4 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain NanE PF04131.14 CAR29720.1 - 9.3e-07 28.2 0.2 1.8e-06 27.3 0.1 1.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase DHO_dh PF01180.21 CAR29720.1 - 1e-06 28.2 2.4 1.3e-06 27.9 1.0 1.8 2 1 0 2 2 2 1 Dihydroorotate dehydrogenase His_biosynth PF00977.21 CAR29720.1 - 0.00013 21.5 0.0 0.0017 17.8 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 CAR29720.1 - 0.005 16.2 0.5 0.012 15.0 0.5 1.6 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Dus PF01207.17 CAR29720.1 - 0.0065 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF561 PF04481.12 CAR29720.1 - 0.019 14.2 1.3 0.02 14.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF561) G3P_antiterm PF04309.12 CAR29720.1 - 0.039 13.4 0.1 0.072 12.5 0.1 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator FMN_dh PF01070.18 CAR29720.1 - 0.07 12.1 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Glyco_transf_4 PF13439.6 CAR29720.1 - 0.2 11.7 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 mRNA_triPase PF02940.15 CAR29721.1 - 1.3e-38 132.9 8.1 3.1e-38 131.7 8.1 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain MINDY_DUB PF04424.13 CAR29721.1 - 1.7e-18 66.7 0.2 6.6e-18 64.8 0.2 2.1 1 1 0 1 1 1 1 MINDY deubiquitinase DUF237 PF03072.14 CAR29721.1 - 0.0024 17.9 0.1 0.006 16.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF237) Membr_traf_MHD PF10540.9 CAR29723.1 - 1.6e-41 141.9 1.8 3.3e-41 140.9 0.0 2.6 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 CAR29723.1 - 2.1e-09 37.6 0.0 5.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 CAR29723.1 - 6.9e-07 28.2 0.3 1.9e-06 26.7 0.3 1.8 1 1 0 1 1 1 1 Plant family of unknown function (DUF810) DpnI_C PF17726.1 CAR29723.1 - 0.13 12.4 2.3 0.81 9.8 2.3 2.4 1 0 0 1 1 1 0 Dam-replacing HTH domain SWIB PF02201.18 CAR29724.1 - 1.5e-28 98.4 0.1 2.7e-27 94.5 0.0 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 CAR29724.1 - 3.5e-12 46.1 0.0 1.3e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 DEK C terminal domain NOA36 PF06524.12 CAR29724.1 - 0.52 9.6 17.9 0.014 14.7 11.8 1.5 2 0 0 2 2 2 0 NOA36 protein eIF_4EBP PF05456.11 CAR29724.1 - 0.88 9.5 5.8 0.62 10.0 0.8 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) FYDLN_acid PF09538.10 CAR29724.1 - 1 10.1 17.5 0.93 10.2 11.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) RXT2_N PF08595.11 CAR29724.1 - 1.6 8.8 13.1 0.094 12.7 5.8 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Pox_Ag35 PF03286.14 CAR29724.1 - 2 8.2 18.9 0.16 11.7 11.3 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CENP-B_dimeris PF09026.10 CAR29724.1 - 3.5 8.1 23.8 81 3.7 23.1 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RRS1 PF04939.12 CAR29725.1 - 2.2e-60 203.2 5.5 2.5e-60 203.0 5.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGEF PF00621.20 CAR29726.1 - 8.1e-16 58.8 2.1 8.1e-16 58.8 2.1 3.5 3 1 1 4 4 4 1 RhoGEF domain Mce4_CUP1 PF11887.8 CAR29726.1 - 0.0044 16.5 0.1 0.0076 15.7 0.1 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative VPS11_C PF12451.8 CAR29727.1 - 1.6e-14 53.8 0.5 1.6e-14 53.8 0.5 2.2 3 0 0 3 3 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 CAR29727.1 - 1.1e-06 28.6 2.8 2.6e-06 27.3 2.8 1.7 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 CAR29727.1 - 0.004 17.1 5.4 0.004 17.1 5.4 2.2 2 0 0 2 2 1 1 zinc-RING finger domain PHD PF00628.29 CAR29727.1 - 0.0091 15.9 3.9 0.023 14.6 3.9 1.8 1 0 0 1 1 1 1 PHD-finger zf-RING_UBOX PF13445.6 CAR29727.1 - 0.0092 16.0 4.8 0.015 15.3 3.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR29727.1 - 0.014 15.3 6.6 0.054 13.4 6.7 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CAR29727.1 - 0.017 14.7 3.3 0.035 13.7 3.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CAR29727.1 - 0.043 13.9 1.1 0.086 12.9 1.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CAR29727.1 - 0.08 13.3 3.8 0.19 12.1 3.8 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Herpes_PAP PF03325.13 CAR29727.1 - 0.086 12.4 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein zf-RING_2 PF13639.6 CAR29727.1 - 0.095 13.0 6.5 0.27 11.6 6.5 1.9 1 0 0 1 1 1 0 Ring finger domain LMBR1 PF04791.16 CAR29727.1 - 0.097 11.6 1.2 0.22 10.4 0.6 1.8 2 0 0 2 2 2 0 LMBR1-like membrane protein KN17_SH3 PF18131.1 CAR29727.1 - 0.17 12.1 2.7 9.4 6.4 0.1 3.0 3 0 0 3 3 3 0 KN17 SH3-like C-terminal domain RNase_PH_C PF03725.15 CAR29727.1 - 0.2 11.7 4.8 21 5.2 0.2 3.7 3 0 0 3 3 3 0 3' exoribonuclease family, domain 2 Prok-RING_4 PF14447.6 CAR29727.1 - 0.52 10.2 3.6 1.1 9.2 3.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CAR29727.1 - 0.53 10.5 7.8 0.58 10.4 4.3 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CAR29727.1 - 2.3 8.1 5.9 6.2 6.8 5.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) S10_plectin PF03501.15 CAR29728.1 - 3.4e-42 142.4 0.3 3.9e-42 142.2 0.3 1.0 1 0 0 1 1 1 1 Plectin/S10 domain MsyB PF13984.6 CAR29728.1 - 0.017 15.4 0.0 0.022 15.1 0.0 1.2 1 0 0 1 1 1 0 MsyB protein DUF4364 PF14277.6 CAR29728.1 - 0.032 14.0 0.2 0.079 12.7 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4364) tRNA-synt_1c_C PF03950.18 CAR29728.1 - 0.068 13.1 0.0 0.073 12.9 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain PadR PF03551.14 CAR29728.1 - 0.072 13.1 0.2 0.072 13.1 0.2 1.7 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Mpv17_PMP22 PF04117.12 CAR29729.1 - 2.2e-19 69.4 1.1 2.2e-19 69.4 1.1 2.4 3 0 0 3 3 3 1 Mpv17 / PMP22 family P5-ATPase PF12409.8 CAR29730.1 - 9.6e-35 119.4 0.0 3.6e-34 117.6 0.0 2.1 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 CAR29730.1 - 1.1e-29 103.2 0.0 2.2e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CAR29730.1 - 3.4e-13 50.4 0.0 8.6e-06 26.2 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAR29730.1 - 4.6e-06 26.6 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CAR29730.1 - 0.0021 17.7 0.0 0.0046 16.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAR29730.1 - 0.18 11.5 0.1 6.8 6.3 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase S1 PF00575.23 CAR29731.1 - 9e-55 182.9 27.9 3.5e-13 49.7 0.3 11.5 10 1 0 10 10 10 8 S1 RNA binding domain TPR_19 PF14559.6 CAR29731.1 - 8e-07 29.5 0.0 0.096 13.2 0.0 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CAR29731.1 - 7.3e-06 26.4 0.4 2.7 9.1 0.0 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 CAR29731.1 - 2.6e-05 24.4 21.2 0.0087 16.1 0.1 4.4 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_12 PF13424.6 CAR29731.1 - 0.00082 19.6 0.1 1 9.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 CAR29731.1 - 0.00091 19.1 0.1 0.51 10.3 0.1 4.4 6 0 0 6 6 6 1 RNase II-type exonuclease C-terminal S1 domain TPR_16 PF13432.6 CAR29731.1 - 0.0016 19.1 0.0 0.12 13.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CAR29731.1 - 0.024 14.6 1.9 0.17 11.8 0.3 2.5 2 0 0 2 2 2 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 CAR29731.1 - 0.025 14.7 0.4 4.8 7.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 CAR29731.1 - 0.099 11.8 7.6 0.93 8.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TRAM PF01938.20 CAR29731.1 - 0.5 10.4 4.0 4.1 7.5 0.0 3.9 4 0 0 4 4 4 0 TRAM domain RrnaAD PF00398.20 CAR29732.1 - 3.1e-60 203.5 0.0 3.6e-60 203.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TAFII55_N PF04658.13 CAR29733.1 - 1.4e-51 174.3 0.0 1.4e-51 174.3 0.0 3.3 3 1 0 3 3 3 1 TAFII55 protein conserved region SNF2_N PF00176.23 CAR29734.1 - 4.7e-73 245.9 0.5 4.7e-73 245.9 0.5 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR29734.1 - 8.3e-22 77.6 0.4 1.4e-19 70.5 0.0 3.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CAR29734.1 - 1.5e-15 57.0 0.6 4.2e-15 55.6 0.6 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 CAR29734.1 - 1.8e-14 54.1 1.7 1.8e-14 54.1 1.7 5.2 6 0 0 6 6 6 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 CAR29734.1 - 1.4e-09 38.2 2.5 2.4e-09 37.4 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.13 CAR29734.1 - 0.00049 20.4 7.8 0.00049 20.4 7.8 4.5 4 0 0 4 4 4 1 HSA AAA_2 PF07724.14 CAR29735.1 - 2.8e-51 174.0 0.1 2.8e-49 167.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CAR29735.1 - 2.5e-35 120.5 0.6 2.5e-35 120.5 0.6 3.0 2 1 1 3 3 2 1 AAA lid domain ClpB_D2-small PF10431.9 CAR29735.1 - 4.6e-25 87.5 1.0 1.6e-24 85.8 0.1 2.6 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CAR29735.1 - 1.9e-22 80.1 0.0 1.7e-11 44.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CAR29735.1 - 8.9e-16 58.1 2.7 8e-12 45.3 0.0 4.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAR29735.1 - 7.6e-12 45.9 1.2 0.00018 22.0 0.1 4.1 2 2 1 4 4 4 2 AAA ATPase domain TniB PF05621.11 CAR29735.1 - 2.9e-07 30.1 0.5 0.00066 19.1 0.0 4.6 4 1 0 4 4 4 1 Bacterial TniB protein AAA_22 PF13401.6 CAR29735.1 - 4.2e-07 30.3 1.4 0.074 13.3 0.1 3.9 3 2 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 CAR29735.1 - 8.4e-07 28.8 0.1 3.8e-05 23.5 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CAR29735.1 - 1.6e-06 28.2 0.0 0.035 14.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 CAR29735.1 - 1.7e-06 28.1 6.9 0.19 11.6 0.0 4.2 4 1 1 5 5 4 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CAR29735.1 - 4.3e-06 27.3 0.6 0.15 12.6 0.0 4.0 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 CAR29735.1 - 8.6e-06 25.6 0.0 0.037 13.8 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 CAR29735.1 - 1.2e-05 24.9 0.1 0.028 14.0 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region ABC_tran PF00005.27 CAR29735.1 - 2.7e-05 24.7 0.2 0.094 13.2 0.0 3.3 3 1 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 CAR29735.1 - 3.2e-05 23.9 0.0 0.037 13.9 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase DUF815 PF05673.13 CAR29735.1 - 0.00016 20.9 1.9 0.69 9.0 0.2 3.7 2 2 0 2 2 2 2 Protein of unknown function (DUF815) AAA_30 PF13604.6 CAR29735.1 - 0.00021 21.0 0.0 1.2 8.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CAR29735.1 - 0.00035 20.6 0.0 1.6 8.8 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CAR29735.1 - 0.00045 20.5 0.0 0.43 10.8 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CAR29735.1 - 0.00047 19.8 0.0 0.12 12.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CAR29735.1 - 0.00075 18.8 0.0 0.0093 15.3 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 CAR29735.1 - 0.00088 19.6 0.1 1.4 9.3 0.1 3.1 2 1 0 2 2 2 1 RNA helicase PduV-EutP PF10662.9 CAR29735.1 - 0.001 18.8 0.0 0.42 10.4 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 CAR29735.1 - 0.001 19.2 0.0 1.8 8.8 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 CAR29735.1 - 0.0011 18.4 0.4 0.72 9.2 0.0 3.8 3 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CAR29735.1 - 0.0013 18.7 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 CAR29735.1 - 0.0014 18.5 0.4 1.1 9.1 0.1 3.6 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_6 PF12774.7 CAR29735.1 - 0.0045 16.0 0.1 0.13 11.2 0.0 2.7 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region Bac_DnaA PF00308.18 CAR29735.1 - 0.0048 16.8 0.2 2 8.2 0.0 3.3 3 0 0 3 3 3 1 Bacterial dnaA protein ResIII PF04851.15 CAR29735.1 - 0.0056 16.7 0.0 0.5 10.3 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 CAR29735.1 - 0.0072 16.0 0.1 1.3 8.6 0.0 2.9 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CAR29735.1 - 0.011 16.0 0.9 13 6.1 0.1 3.7 2 2 1 4 4 4 0 AAA domain AAA_24 PF13479.6 CAR29735.1 - 0.016 14.9 0.0 7.1 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAR29735.1 - 0.022 14.4 0.0 1 8.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 CAR29735.1 - 0.025 14.7 0.0 2.1 8.5 0.0 3.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 CAR29735.1 - 0.028 14.9 12.1 8.4 6.8 3.5 3.8 3 1 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CAR29735.1 - 0.033 14.3 0.0 7 6.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain Torsin PF06309.11 CAR29735.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Torsin T2SSE PF00437.20 CAR29735.1 - 0.038 13.0 0.2 0.16 11.0 0.1 2.1 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_3 PF07726.11 CAR29735.1 - 0.045 13.6 0.1 0.78 9.6 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 CAR29735.1 - 0.055 13.5 2.0 1.1 9.3 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 CAR29735.1 - 0.056 13.2 0.0 7.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 CAR29735.1 - 0.07 13.0 0.2 23 4.9 0.0 3.3 3 0 0 3 3 3 0 NTPase PhoH PF02562.16 CAR29735.1 - 0.077 12.4 0.0 3.2 7.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein LacI PF00356.21 CAR29735.1 - 0.089 12.6 0.0 9.3 6.1 0.1 3.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF416 PF04222.12 CAR29735.1 - 1.7 8.0 5.8 2.3 7.6 5.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF416) HSP20 PF00011.21 CAR29736.1 - 2.4e-22 79.0 4.2 3.1e-22 78.6 4.2 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CAR29736.1 - 1.5e-08 34.1 0.1 3.1e-08 33.0 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF1801 PF08818.11 CAR29736.1 - 0.087 13.3 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DU1801) Apc13p PF05839.11 CAR29737.1 - 1.7e-12 47.4 1.7 5.2e-11 42.6 0.8 2.1 2 0 0 2 2 2 2 Apc13p protein Cellulase PF00150.18 CAR29738.1 - 1.4e-15 57.4 3.0 3.2e-15 56.3 3.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PalH PF08733.10 CAR29739.1 - 1.3e-90 303.8 20.6 1.6e-90 303.5 20.6 1.1 1 0 0 1 1 1 1 PalH/RIM21 Vps55 PF04133.14 CAR29739.1 - 0.1 12.6 3.1 0.13 12.2 0.4 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting 55 TFCD_C PF12612.8 CAR29740.1 - 2.2e-10 40.7 7.0 8.5 6.2 0.0 9.6 4 3 6 10 10 10 2 Tubulin folding cofactor D C terminal MCR_beta PF02241.18 CAR29740.1 - 2.2e-05 24.2 0.6 9.3 5.8 0.0 4.9 2 2 1 4 4 4 3 Methyl-coenzyme M reductase beta subunit, C-terminal domain DUF1353 PF07087.11 CAR29740.1 - 0.00034 20.3 31.4 2.8 7.7 0.1 9.7 2 2 7 9 9 9 5 Protein of unknown function (DUF1353) DUF5132 PF17195.4 CAR29740.1 - 0.00043 20.3 50.5 15 5.8 0.0 14.2 17 0 0 17 17 17 0 Protein of unknown function (DUF5132) DUF5330 PF17264.2 CAR29740.1 - 0.0018 18.3 22.2 22 5.1 0.1 9.1 3 2 7 13 13 12 0 Family of unknown function (DUF5330) KH_9 PF17904.1 CAR29740.1 - 0.0019 18.5 3.5 1.4e+02 3.0 0.0 7.3 2 1 5 7 7 7 0 FMRP KH0 domain Fasciclin PF02469.22 CAR29740.1 - 0.036 14.3 0.2 0.17 12.1 0.2 2.2 1 1 0 1 1 1 0 Fasciclin domain ZipA_C PF04354.13 CAR29740.1 - 0.054 13.4 1.4 3.2e+02 1.2 0.0 6.4 7 1 1 8 8 8 0 ZipA, C-terminal FtsZ-binding domain PYRIN PF02758.16 CAR29740.1 - 0.11 12.7 0.1 24 5.1 0.0 5.0 6 0 0 6 6 6 0 PAAD/DAPIN/Pyrin domain NitrOD1 PF18549.1 CAR29740.1 - 0.14 12.1 0.8 1.4e+02 2.6 0.0 4.2 3 0 0 3 3 3 0 Nitrosopumilus output domain 1 tRNA-Thr_ED PF08915.11 CAR29740.1 - 2.3 8.3 11.8 24 5.0 0.6 4.0 2 1 0 3 3 3 0 Archaea-specific editing domain of threonyl-tRNA synthetase TPR_20 PF14561.6 CAR29740.1 - 3.4 8.0 33.5 8.4 6.8 0.2 8.7 3 3 4 10 10 10 0 Tetratricopeptide repeat HLH PF00010.26 CAR29741.1 - 1.4e-17 63.4 0.2 3.6e-17 62.1 0.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Androgen_recep PF02166.16 CAR29741.1 - 5.3 5.8 21.2 2.5 6.8 5.0 2.3 2 0 0 2 2 2 0 Androgen receptor GHMP_kinases_N PF00288.26 CAR29742.1 - 9.4e-10 38.6 0.0 2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CAR29742.1 - 2.8e-05 24.4 0.0 7.7e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal ATP-synt_C PF00137.21 CAR29743.1 - 3.6e-24 84.9 29.5 1.6e-15 57.2 11.7 2.3 2 0 0 2 2 2 2 ATP synthase subunit C RPN1_RPN2_N PF17781.1 CAR29744.1 - 1.6e-113 379.2 1.1 3.6e-113 378.1 0.6 1.8 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 CAR29744.1 - 2.1e-29 100.4 13.6 7.4e-08 32.4 0.3 8.7 10 0 0 10 10 10 5 Proteasome/cyclosome repeat RPN1_C PF18051.1 CAR29744.1 - 5.9e-29 99.9 0.1 1.1e-28 99.0 0.1 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal HEAT_2 PF13646.6 CAR29744.1 - 1.1e-05 25.8 0.9 0.49 10.8 0.0 4.7 5 1 1 6 6 6 2 HEAT repeats XET_C PF06955.12 CAR29744.1 - 0.15 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus RP-C_C PF11800.8 CAR29744.1 - 6.1 6.9 7.9 1 9.4 0.5 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region DPPIV_N PF00930.21 CAR29745.1 - 6.3e-100 334.4 4.9 8.6e-100 333.9 4.9 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CAR29745.1 - 1.2e-51 175.2 2.1 2.2e-51 174.4 2.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CAR29745.1 - 4.3e-05 24.2 0.0 0.0013 19.4 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 CAR29745.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 CAR29745.1 - 0.075 12.8 0.1 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CAR29745.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.25 CAR29746.1 - 4.7e-63 213.0 0.0 7.1e-63 212.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29746.1 - 7.1e-31 107.4 0.0 1.2e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR29746.1 - 0.004 16.2 0.0 0.0097 14.9 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain WD40 PF00400.32 CAR29746.1 - 0.02 15.7 0.0 0.079 13.9 0.0 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat APH PF01636.23 CAR29746.1 - 0.069 13.1 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family DNA_primase_S PF01896.19 CAR29746.1 - 0.08 13.0 0.4 4 7.5 0.1 2.2 2 0 0 2 2 2 0 DNA primase small subunit PIF1 PF05970.14 CAR29747.1 - 1.1e-52 179.4 0.8 2.4e-43 148.7 0.3 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 CAR29747.1 - 4.4e-23 82.0 0.0 6.7e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CAR29747.1 - 8e-09 36.0 0.0 1.7e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAR29747.1 - 1.5e-05 25.3 0.0 6.3e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.14 CAR29747.1 - 8.8e-05 20.6 0.1 0.0019 16.2 0.0 2.1 2 0 0 2 2 2 1 Helicase AAA_7 PF12775.7 CAR29747.1 - 0.00017 21.2 0.1 0.00037 20.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region PhoH PF02562.16 CAR29747.1 - 0.0014 18.2 0.1 0.027 14.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein SH3_13 PF18335.1 CAR29747.1 - 0.0027 17.5 0.2 0.0077 16.0 0.0 1.9 2 0 0 2 2 1 1 ATP-dependent RecD-like DNA helicase SH3 domain T2SSE PF00437.20 CAR29747.1 - 0.0038 16.3 0.2 0.007 15.5 0.2 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 CAR29747.1 - 0.039 13.3 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 CAR29747.1 - 0.046 13.0 0.1 0.1 11.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 CAR29747.1 - 0.052 13.3 1.7 2.8 7.6 0.1 3.2 3 1 0 3 3 2 0 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CAR29747.1 - 0.087 12.7 0.7 0.54 10.1 0.7 2.2 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.29 CAR29747.1 - 0.093 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 CAR29747.1 - 0.11 11.8 0.2 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activat PF00158.26 CAR29747.1 - 0.14 11.9 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Helicase_RecD PF05127.14 CAR29747.1 - 0.17 11.7 0.3 0.69 9.8 0.3 2.0 1 1 0 1 1 1 0 Helicase MatE PF01554.18 CAR29748.1 - 4.1e-65 218.3 32.0 2e-37 128.3 10.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 CAR29748.1 - 0.0014 18.7 2.0 0.0014 18.7 2.0 3.8 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Phage_CI_C PF16452.5 CAR29748.1 - 0.093 13.0 0.1 5.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage CI repressor C-terminal domain Ribosomal_L1 PF00687.21 CAR29749.1 - 2.2e-35 122.2 0.6 4e-35 121.4 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF1533 PF07550.11 CAR29749.1 - 0.039 13.8 0.0 0.75 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) Elf1 PF05129.13 CAR29750.1 - 6.3e-30 103.1 1.5 8.1e-30 102.7 1.5 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF4611 PF15387.6 CAR29750.1 - 0.009 16.2 0.7 0.009 16.2 0.7 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4611) Drc1-Sld2 PF11719.8 CAR29750.1 - 0.014 14.9 0.1 0.014 14.9 0.1 1.9 1 1 1 2 2 2 0 DNA replication and checkpoint protein Mpp10 PF04006.12 CAR29750.1 - 0.029 12.8 10.3 0.039 12.4 10.3 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIA PF03153.13 CAR29750.1 - 0.59 10.1 10.4 0.55 10.2 10.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-3c_N PF05470.12 CAR29750.1 - 1.2 7.3 5.0 1.1 7.5 5.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus zf-FCS PF06467.14 CAR29750.1 - 1.4 8.9 7.2 36 4.4 7.5 2.1 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif BUD22 PF09073.10 CAR29750.1 - 2.6 7.3 13.4 3.1 7.0 13.4 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 CAR29750.1 - 3.1 7.1 18.2 3.7 6.9 18.2 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CAR29750.1 - 3.7 5.7 11.2 4.7 5.4 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein COX5A PF02284.16 CAR29751.1 - 8.9e-40 134.9 0.6 1.3e-39 134.4 0.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF1266 PF06889.11 CAR29751.1 - 0.11 12.5 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) Calcipressin PF04847.12 CAR29752.1 - 7.9e-17 61.6 0.4 1.6e-16 60.6 0.4 1.5 1 1 0 1 1 1 1 Calcipressin DUF1425 PF07233.12 CAR29752.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) Nramp PF01566.18 CAR29753.1 - 1.3e-90 303.9 14.8 2.7e-90 303.0 13.4 1.9 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DUF4342 PF14242.6 CAR29753.1 - 0.19 11.8 1.6 0.9 9.6 1.6 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) FSH1 PF03959.13 CAR29754.1 - 3.2e-62 209.9 0.0 3.6e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CAR29754.1 - 0.0062 16.4 0.4 3 7.6 0.3 2.7 3 1 0 3 3 3 2 Phospholipase/Carboxylesterase BAAT_C PF08840.11 CAR29754.1 - 0.0082 16.1 0.0 2.9 7.8 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal LapA_dom PF06305.11 CAR29755.1 - 0.14 12.0 1.6 3.6 7.5 0.0 3.2 3 1 0 3 3 3 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 CAR29756.1 - 2.9e-32 112.0 32.5 2.9e-32 112.0 32.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR29756.1 - 6.3e-07 28.6 34.9 1.9e-06 27.1 34.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_M1 PF01433.20 CAR29757.1 - 1.7e-86 289.3 5.0 3.4e-86 288.3 3.9 2.0 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CAR29757.1 - 4.8e-79 266.2 4.4 7.5e-79 265.5 2.1 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CAR29757.1 - 8.1e-52 176.1 0.4 1.9e-51 174.9 0.4 1.7 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Inositol_P PF00459.25 CAR29758.1 - 7.9e-66 222.3 0.0 8.7e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family RNase_H2-Ydr279 PF09468.10 CAR29760.1 - 2.3e-19 70.2 1.1 5.9e-18 65.6 0.1 2.7 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 CAR29760.1 - 2.7e-14 53.2 0.0 5.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RNase_PH PF01138.21 CAR29761.1 - 3.1e-20 73.0 0.0 4.8e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CAR29761.1 - 6.7e-16 58.1 0.1 7.9e-15 54.6 0.0 2.3 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 HAD_2 PF13419.6 CAR29763.1 - 1.8e-15 57.5 0.0 3.2e-15 56.6 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CAR29763.1 - 1.5e-07 32.0 0.0 0.00021 21.6 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CAR29763.1 - 0.015 15.3 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like HAD PF12710.7 CAR29763.1 - 0.17 12.3 0.0 0.58 10.5 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF155 PF02582.14 CAR29764.1 - 4.1e-44 150.8 0.0 6.3e-44 150.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 FAD_binding_1 PF00667.20 CAR29765.1 - 1.6e-68 230.6 0.0 2.8e-68 229.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CAR29765.1 - 6.6e-28 97.7 1.0 1.1e-27 97.0 1.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CAR29765.1 - 5.3e-22 78.5 0.0 1.6e-21 77.0 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Spore_IV_A PF09547.10 CAR29765.1 - 0.05 12.5 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Flavodoxin_5 PF12724.7 CAR29765.1 - 0.18 12.0 0.3 0.93 9.7 0.1 2.3 2 1 0 2 2 2 0 Flavodoxin domain MAGE PF01454.19 CAR29766.1 - 1.4e-44 152.4 0.0 2.2e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 MAGE family Inositol_P PF00459.25 CAR29767.1 - 3.1e-70 236.8 0.0 3.5e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF836 PF05768.14 CAR29768.1 - 4e-15 56.0 0.2 4.6e-15 55.8 0.2 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 CAR29768.1 - 0.0093 16.2 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CAR29768.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain Ras_bdg_2 PF14847.6 CAR29768.1 - 0.025 14.9 0.1 0.031 14.6 0.1 1.2 1 0 0 1 1 1 0 Ras-binding domain of Byr2 CALCOCO1 PF07888.11 CAR29769.1 - 0.0037 16.2 17.6 0.0037 16.2 17.6 3.8 2 1 1 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_TATA_bd PF12325.8 CAR29769.1 - 0.013 15.7 3.4 0.013 15.7 3.4 7.1 2 2 5 7 7 7 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 CAR29769.1 - 1.2 7.6 5.2 2.5 6.5 5.2 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family PAP2 PF01569.21 CAR29770.1 - 1.8e-23 82.8 0.2 1.8e-23 82.8 0.2 2.2 1 1 1 2 2 2 1 PAP2 superfamily HisKA_7TM PF16927.5 CAR29770.1 - 0.47 10.5 10.3 0.3 11.1 6.2 2.0 2 0 0 2 2 2 0 N-terminal 7TM region of histidine kinase HGTP_anticodon2 PF12745.7 CAR29771.1 - 1.7e-90 303.1 0.0 1.7e-90 303.1 0.0 2.6 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 CAR29771.1 - 1.9e-69 233.9 9.2 4.4e-43 147.6 0.2 4.1 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29771.1 - 7.9e-38 130.2 0.2 2.9e-22 79.2 0.1 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 CAR29771.1 - 5.1e-18 65.4 4.1 2e-17 63.5 4.1 2.2 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 CAR29771.1 - 3.7e-14 52.7 0.0 8.9e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 Histidyl-tRNA synthetase FTA2 PF13095.6 CAR29771.1 - 0.00092 18.9 2.1 0.65 9.6 0.1 3.7 4 0 0 4 4 4 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CAR29771.1 - 0.014 14.7 0.0 1.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 CAR29771.1 - 0.031 14.2 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CAR29771.1 - 0.65 9.6 7.9 0.12 11.9 0.1 2.7 2 0 0 2 2 2 0 RIO1 family Med20 PF08612.11 CAR29772.1 - 3.1e-44 151.0 0.0 3.4e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex CTD_bind PF04818.13 CAR29773.1 - 3e-14 53.6 0.4 8.6e-14 52.1 0.4 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Cor1 PF04803.12 CAR29773.1 - 0.0024 18.1 5.7 2.6 8.3 0.1 3.3 2 1 1 3 3 3 2 Cor1/Xlr/Xmr conserved region Elf4 PF07011.11 CAR29773.1 - 0.01 15.7 0.9 0.053 13.4 0.3 2.2 2 0 0 2 2 2 0 Early Flowering 4 domain SMC_Nse1 PF07574.13 CAR29773.1 - 0.011 15.7 0.9 0.017 15.0 0.9 1.4 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex CTK3 PF12243.8 CAR29773.1 - 0.012 15.6 0.7 0.031 14.3 0.2 1.9 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 Chalcone PF02431.15 CAR29773.1 - 0.058 12.8 0.1 0.13 11.6 0.1 1.7 1 0 0 1 1 1 0 Chalcone-flavanone isomerase BUD22 PF09073.10 CAR29773.1 - 2.4 7.4 17.3 3.5 6.9 17.3 1.2 1 0 0 1 1 1 0 BUD22 DEAD PF00270.29 CAR29774.1 - 1.5e-25 89.9 0.2 2.4e-23 82.8 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF1998 PF09369.10 CAR29774.1 - 2.3e-20 73.1 0.2 7.6e-20 71.5 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 CAR29774.1 - 1.5e-13 51.0 0.2 3.4e-12 46.7 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR29774.1 - 1.1e-07 32.0 0.4 3.1e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 CAR29774.1 - 0.00016 22.0 0.2 0.00044 20.6 0.2 1.7 1 0 0 1 1 1 1 DNA replication factor CDT1 like SRX PF09201.10 CAR29775.1 - 5.6e-66 220.9 0.1 1.2e-65 219.9 0.1 1.6 1 0 0 1 1 1 1 SRX, signal recognition particle receptor alpha subunit SRP54 PF00448.22 CAR29775.1 - 1.1e-46 158.9 0.1 4.1e-44 150.6 0.1 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CAR29775.1 - 1.5e-08 34.9 5.5 3e-08 33.9 5.5 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 CAR29775.1 - 1.5e-06 28.3 1.6 1.2e-05 25.5 0.2 2.7 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArsA_ATPase PF02374.15 CAR29775.1 - 0.00027 20.2 0.2 0.0095 15.1 0.2 2.4 1 1 0 1 1 1 1 Anion-transporting ATPase MeaB PF03308.16 CAR29775.1 - 0.00056 19.0 0.0 0.0015 17.6 0.0 1.8 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 CAR29775.1 - 0.0013 18.7 0.2 0.013 15.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 CAR29775.1 - 0.0016 18.5 0.0 0.0079 16.3 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 CAR29775.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CAR29775.1 - 0.032 14.4 0.0 0.086 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CAR29775.1 - 0.081 12.7 0.0 0.45 10.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CAR29775.1 - 0.12 12.5 0.2 0.84 9.7 0.2 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase Cyt-b5 PF00173.28 CAR29776.1 - 1.4e-14 54.0 0.0 2.6e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sde2_N_Ubi PF13019.6 CAR29776.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain zf-HIT PF04438.16 CAR29777.1 - 4.2e-09 36.1 8.5 7.4e-09 35.3 8.5 1.4 1 0 0 1 1 1 1 HIT zinc finger YL1 PF05764.13 CAR29777.1 - 0.07 13.2 9.6 0.15 12.2 9.6 1.5 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.10 CAR29777.1 - 0.51 9.6 12.3 0.9 8.8 12.3 1.4 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 CAR29777.1 - 1.1 7.4 11.6 1.9 6.7 11.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CAR29777.1 - 1.3 7.7 4.1 2.1 7.0 4.1 1.2 1 0 0 1 1 1 0 Presenilin PPP4R2 PF09184.11 CAR29777.1 - 2 8.0 12.6 27 4.2 10.5 2.3 2 1 0 2 2 2 0 PPP4R2 Packaging_FI PF14000.6 CAR29777.1 - 2.4 8.6 9.6 4.3 7.8 9.6 1.4 1 0 0 1 1 1 0 DNA packaging protein FI Sporozoite_P67 PF05642.11 CAR29777.1 - 4.6 5.2 9.8 6.9 4.6 9.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 CAR29777.1 - 5.8 5.0 14.3 9.1 4.4 14.3 1.2 1 0 0 1 1 1 0 Nop14-like family V-ATPase_G PF03179.15 CAR29778.1 - 7e-32 110.1 12.5 7.9e-32 109.9 12.5 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit V-ATPase_G_2 PF16999.5 CAR29778.1 - 0.00093 19.6 11.6 0.0012 19.3 11.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DFF40 PF09230.10 CAR29778.1 - 0.0087 15.7 4.7 0.0095 15.6 4.7 1.0 1 0 0 1 1 1 1 DNA fragmentation factor 40 kDa ATP-synt_B PF00430.18 CAR29778.1 - 0.011 15.8 15.0 0.024 14.7 13.1 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) HIP1_clath_bdg PF16515.5 CAR29778.1 - 0.069 13.8 10.2 0.1 13.2 10.2 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Phasin PF05597.11 CAR29778.1 - 0.11 12.5 7.5 0.14 12.1 7.5 1.1 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FliD_N PF02465.18 CAR29778.1 - 0.33 11.7 5.5 0.48 11.2 5.2 1.4 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus HSCB_C PF07743.13 CAR29778.1 - 0.59 10.7 6.7 0.48 11.0 2.7 2.1 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain DUF3552 PF12072.8 CAR29778.1 - 1.4 8.3 17.6 0.091 12.2 10.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) vATP-synt_E PF01991.18 CAR29778.1 - 1.5 8.2 15.2 2.7 7.3 15.2 1.4 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Atrophin-1 PF03154.15 CAR29778.1 - 3 6.0 5.9 3.1 6.0 5.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family KfrA_N PF11740.8 CAR29778.1 - 3.8 8.2 10.6 1.4 9.6 5.0 2.0 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF4407 PF14362.6 CAR29778.1 - 3.9 6.7 8.2 4.8 6.4 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 CAR29778.1 - 4.2 8.1 8.8 11 6.7 8.8 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) RNase_J_C PF17770.1 CAR29778.1 - 8.7 7.5 8.4 24 6.0 2.8 2.1 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain Aldedh PF00171.22 CAR29779.1 - 7.8e-124 413.7 0.0 9.1e-124 413.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Antimicrobial15 PF08110.12 CAR29779.1 - 0.068 13.4 1.3 3.1 8.2 0.0 3.3 3 0 0 3 3 3 0 Ocellatin family RRF PF01765.19 CAR29780.1 - 3.8e-38 131.0 7.2 3.8e-38 131.0 7.2 1.4 2 0 0 2 2 2 1 Ribosome recycling factor ApoO PF09769.9 CAR29780.1 - 0.16 11.9 2.3 3.2 7.7 0.2 2.5 2 1 0 2 2 2 0 Apolipoprotein O ATP19 PF11022.8 CAR29780.1 - 0.18 12.2 0.5 0.18 12.2 0.5 1.8 2 0 0 2 2 2 0 ATP synthase subunit K Annexin PF00191.20 CAR29780.1 - 0.37 10.9 0.1 0.37 10.9 0.1 2.3 3 0 0 3 3 3 0 Annexin DNA_repr_REX1B PF14966.6 CAR29780.1 - 0.58 10.8 5.5 0.22 12.2 1.5 2.1 2 0 0 2 2 2 0 DNA repair REX1-B NPV_P10 PF05531.12 CAR29780.1 - 3.9 8.0 6.5 1.2 9.7 2.8 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SKA2 PF16740.5 CAR29780.1 - 6.5 6.6 11.4 0.28 11.0 3.6 2.7 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 RNB PF00773.19 CAR29781.1 - 5.5e-56 190.3 0.0 9.2e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CAR29781.1 - 5.6e-24 84.0 0.0 1.8e-23 82.4 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CAR29781.1 - 5.2e-22 78.0 0.0 1.9e-21 76.2 0.0 2.1 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 CAR29781.1 - 3e-06 27.3 0.1 0.0002 21.5 0.0 3.0 3 0 0 3 3 3 1 Cold shock domain Rrp44_CSD1 PF17216.3 CAR29781.1 - 0.0033 17.1 0.1 0.0033 17.1 0.1 2.4 2 0 0 2 2 2 1 Rrp44-like cold shock domain OB_RNB PF08206.11 CAR29781.1 - 0.016 14.9 0.0 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Rrp44_S1 PF17215.3 CAR29781.1 - 0.069 13.1 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 S1 domain Aldedh PF00171.22 CAR29782.1 - 2.2e-102 343.0 0.0 2.6e-102 342.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Brr6_like_C_C PF10104.9 CAR29783.1 - 7.9e-41 138.9 0.9 1.1e-40 138.4 0.9 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Pyridoxal_deC PF00282.19 CAR29784.1 - 2.6e-23 82.4 0.0 3.8e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CAR29784.1 - 4.9e-09 35.6 0.0 1.7e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CAR29784.1 - 5.8e-06 25.8 0.0 9.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HDA2-3 PF11496.8 CAR29785.1 - 5.9e-71 239.0 0.8 5.9e-71 239.0 0.8 2.2 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DivIC PF04977.15 CAR29785.1 - 0.21 11.4 13.7 2.2 8.1 5.1 3.9 3 1 0 3 3 3 0 Septum formation initiator YabA PF06156.13 CAR29785.1 - 0.22 12.2 13.3 0.035 14.7 5.6 3.2 1 1 2 3 3 3 0 Initiation control protein YabA Mod_r PF07200.13 CAR29785.1 - 0.42 10.7 23.2 0.054 13.6 13.4 3.3 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HalX PF08663.10 CAR29785.1 - 2.5 8.5 6.9 15 6.0 4.9 3.3 2 1 0 2 2 2 0 HalX domain Fez1 PF06818.15 CAR29785.1 - 7.1 7.0 23.7 6.3 7.2 5.1 2.5 1 1 1 2 2 2 0 Fez1 Sec23_trunk PF04811.15 CAR29786.1 - 7.5e-11 42.1 0.1 1.5e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CAR29786.1 - 1.3e-06 29.1 0.0 2.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CAR29786.1 - 0.00045 20.0 0.1 0.0012 18.6 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CAR29786.1 - 0.0023 17.9 2.8 0.0086 16.1 2.8 2.1 1 1 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CAR29786.1 - 0.0068 16.3 0.0 0.017 15.0 0.0 1.8 1 1 0 1 1 1 1 Gelsolin repeat PHD PF00628.29 CAR29786.1 - 0.31 10.9 2.6 3.6 7.5 0.3 2.4 2 0 0 2 2 2 0 PHD-finger Mhr1 PF12829.7 CAR29787.1 - 2.4e-27 94.8 0.4 5.1e-27 93.8 0.4 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination FA_hydroxylase PF04116.13 CAR29788.1 - 1.3e-22 80.6 17.3 2.4e-22 79.7 11.7 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily OSCP PF00213.18 CAR29789.1 - 8.7e-44 149.7 3.4 1e-43 149.5 3.4 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Pam16 PF03656.13 CAR29790.1 - 5e-42 142.9 0.7 5.9e-42 142.7 0.7 1.0 1 0 0 1 1 1 1 Pam16 PHD PF00628.29 CAR29791.1 - 5.6e-10 39.0 8.0 1.3e-09 37.8 8.0 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 CAR29791.1 - 6.4e-08 33.2 0.0 2.7e-07 31.1 0.0 2.2 2 1 0 2 2 2 1 SET domain PHD_2 PF13831.6 CAR29791.1 - 0.0015 18.1 3.1 0.0028 17.2 3.1 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 CAR29791.1 - 0.21 11.6 2.5 0.51 10.4 2.5 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger Pkinase PF00069.25 CAR29792.1 - 1.6e-52 178.5 0.1 2.2e-50 171.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29792.1 - 3.8e-26 91.9 0.7 2.6e-24 85.9 0.1 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CAR29792.1 - 0.00017 20.7 0.0 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 CAR29792.1 - 0.038 13.3 0.1 0.07 12.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ThrE PF06738.12 CAR29793.1 - 1e-66 224.8 17.6 3.3e-62 210.0 8.0 2.1 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CAR29793.1 - 1.3e-10 41.5 7.5 1.3e-10 41.5 7.5 2.3 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE BP28CT PF08146.12 CAR29794.1 - 3.2e-37 127.8 1.2 3.2e-37 127.8 1.2 3.4 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 CAR29794.1 - 1.1e-20 74.2 1.5 1.1e-20 74.2 1.5 5.9 6 1 1 7 7 7 1 U3 small nucleolar RNA-associated protein 10 DUF3385 PF11865.8 CAR29794.1 - 1.1e-05 25.4 14.3 0.059 13.3 0.3 6.2 6 0 0 6 6 6 3 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 CAR29794.1 - 0.019 15.3 2.1 6.5 7.2 0.0 4.6 5 0 0 5 5 5 0 HEAT repeats NuA4 PF09340.10 CAR29795.1 - 5.1e-25 87.1 1.3 7.7e-25 86.6 1.3 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 BRE1 PF08647.11 CAR29795.1 - 0.013 15.5 2.0 0.02 15.0 2.0 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase RE_NgoPII PF09521.10 CAR29795.1 - 0.078 12.1 1.0 0.11 11.6 1.0 1.2 1 0 0 1 1 1 0 NgoPII restriction endonuclease Actin PF00022.19 CAR29796.1 - 3.2e-50 170.9 0.4 2e-38 132.1 0.0 2.2 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.13 CAR29796.1 - 9e-05 21.4 0.0 0.048 12.5 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Gln-synt_C PF00120.24 CAR29797.1 - 8e-19 67.8 0.0 1.9e-17 63.3 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CAR29797.1 - 5.5e-12 45.2 0.0 9.9e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain V-ATPase_H_N PF03224.14 CAR29798.1 - 1.5e-60 205.1 11.8 1.5e-60 205.1 11.8 1.4 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CAR29798.1 - 1.1e-39 135.2 0.2 1.1e-39 135.2 0.2 2.9 3 1 1 4 4 4 1 V-ATPase subunit H Arm PF00514.23 CAR29798.1 - 0.04 14.0 0.0 13 6.0 0.0 3.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat GatB_Yqey PF02637.18 CAR29798.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.8 4 0 0 4 4 4 0 GatB domain PCI PF01399.27 CAR29799.1 - 2.8e-10 40.6 0.7 6.3e-10 39.5 0.1 2.0 2 1 0 2 2 2 1 PCI domain TPR_2 PF07719.17 CAR29799.1 - 0.22 11.7 1.4 0.54 10.5 1.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAR29799.1 - 0.77 10.1 3.2 4.3 7.7 0.8 3.0 3 1 1 4 4 4 0 Tetratricopeptide repeat Tmemb_14 PF03647.13 CAR29800.1 - 4.2e-23 81.9 7.8 4.6e-23 81.8 7.8 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 CAR29800.1 - 0.32 11.3 3.5 0.39 11.0 1.9 1.9 1 1 1 2 2 2 0 Altered inheritance of mitochondria protein 19 G-gamma PF00631.22 CAR29801.1 - 1.5e-23 82.5 0.0 1.9e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 GGL domain Evr1_Alr PF04777.13 CAR29802.1 - 1.2e-24 86.7 0.2 1.7e-24 86.1 0.2 1.3 1 0 0 1 1 1 1 Erv1 / Alr family TIP41 PF04176.13 CAR29803.1 - 6.5e-67 224.3 1.3 8.8e-67 223.9 1.3 1.2 1 0 0 1 1 1 1 TIP41-like family TPR_2 PF07719.17 CAR29804.1 - 3.2e-06 26.8 0.0 2.3e-05 24.2 0.0 2.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CAR29804.1 - 1.2e-05 25.1 0.0 0.0031 17.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CAR29804.1 - 0.00037 20.6 0.0 0.00078 19.5 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CAR29804.1 - 0.00066 19.3 0.4 0.0019 17.8 0.4 1.9 1 0 0 1 1 1 1 TPR repeat DUF5588 PF17826.1 CAR29804.1 - 0.00069 18.6 0.3 0.031 13.2 0.0 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5588) TPR_14 PF13428.6 CAR29804.1 - 0.0021 18.7 0.1 0.012 16.4 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CAR29804.1 - 0.0043 17.5 0.0 0.016 15.7 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CAR29804.1 - 0.0062 16.3 0.0 0.023 14.5 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 CAR29804.1 - 0.034 14.8 1.9 1 10.1 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CAR29804.1 - 0.068 13.8 0.0 0.18 12.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PMC2NT PF08066.12 CAR29804.1 - 0.44 11.3 4.0 28 5.5 0.1 3.3 2 1 0 2 2 2 0 PMC2NT (NUC016) domain eIF-5_eIF-2B PF01873.17 CAR29805.1 - 1.2e-37 128.4 0.0 2.1e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CAR29805.1 - 2.5e-22 78.8 0.0 2.5e-22 78.8 0.0 2.9 3 1 1 4 4 4 1 eIF4-gamma/eIF5/eIF2-epsilon YjbH PF06082.11 CAR29805.1 - 0.16 10.8 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH F-box-like PF12937.7 CAR29806.1 - 3.3e-09 36.5 0.5 1e-08 34.9 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CAR29806.1 - 1.9e-06 27.6 0.4 6.5e-06 25.9 0.4 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 CAR29806.1 - 0.00011 22.5 9.5 4.2 7.9 1.3 6.5 4 1 1 6 6 6 2 Leucine Rich repeats (2 copies) DUF1699 PF08004.11 CAR29806.1 - 0.00024 20.8 0.2 0.79 9.4 0.0 4.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1699) DUF4726 PF15855.5 CAR29806.1 - 0.43 10.8 2.4 12 6.2 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4726) LRR_6 PF13516.6 CAR29806.1 - 0.53 10.5 10.2 8.2 6.8 0.1 6.8 8 0 0 8 8 8 0 Leucine Rich repeat LRR_1 PF00560.33 CAR29806.1 - 0.69 10.7 6.9 45 5.2 0.6 6.1 4 1 0 4 4 4 0 Leucine Rich Repeat PUF PF00806.19 CAR29807.1 - 1.6e-27 93.6 1.8 0.00028 20.4 0.0 6.8 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 CAR29807.1 - 7.3e-08 32.1 0.0 2.3e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PH PF00169.29 CAR29808.1 - 3.3e-06 27.6 0.2 1e-05 26.0 0.0 2.0 2 0 0 2 2 2 1 PH domain Fip1 PF05182.13 CAR29809.1 - 1.1e-20 72.8 1.1 1.1e-20 72.8 1.1 1.8 2 0 0 2 2 2 1 Fip1 motif TFIIF_alpha PF05793.12 CAR29809.1 - 2.1 6.8 14.2 2.7 6.5 14.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) AF-4 PF05110.13 CAR29809.1 - 5.6 4.9 14.4 5.9 4.9 14.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Nop14 PF04147.12 CAR29809.1 - 6 4.9 10.1 6.7 4.8 10.1 1.0 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 CAR29809.1 - 7.1 5.3 4.8 8.9 5.0 4.8 1.1 1 0 0 1 1 1 0 Presenilin Fungal_trans PF04082.18 CAR29810.1 - 4.9e-29 101.2 4.7 4.9e-29 101.2 4.7 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR29810.1 - 4.7e-08 33.0 10.7 8.1e-08 32.3 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pepsin-I3 PF06394.13 CAR29810.1 - 0.063 13.5 1.1 0.2 11.9 0.1 2.4 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain Ribosomal_L37ae PF01780.19 CAR29812.1 - 1.7e-39 133.8 8.8 1.9e-39 133.6 8.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 CAR29812.1 - 0.00065 19.8 3.5 0.00094 19.3 3.5 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 CAR29812.1 - 0.0039 17.1 2.9 0.0066 16.4 2.9 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain CarbpepA_inh PF02977.15 CAR29812.1 - 0.05 13.4 4.0 0.068 13.0 1.2 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-BED PF02892.15 CAR29812.1 - 0.055 13.5 4.0 1.6 8.9 0.2 2.2 1 1 1 2 2 2 0 BED zinc finger DUF2175 PF09943.9 CAR29812.1 - 0.13 12.5 0.3 5.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) ZirS_C PF16583.5 CAR29812.1 - 0.19 11.3 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain zf-C4_ClpX PF06689.13 CAR29812.1 - 1.6 8.7 4.5 5.3 7.0 4.5 2.0 1 1 0 1 1 1 0 ClpX C4-type zinc finger Mito_carr PF00153.27 CAR29813.1 - 6.8e-70 231.1 0.3 8.5e-24 83.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.21 CAR29814.1 - 8.9e-41 140.0 0.0 1.8e-30 106.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Resolvase PF00239.21 CAR29814.1 - 0.051 13.7 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Resolvase, N terminal domain Peptidase_C12 PF01088.21 CAR29815.1 - 2.9e-42 144.8 0.0 3.4e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 LHH PF14411.6 CAR29815.1 - 0.037 14.2 0.0 0.1 12.8 0.0 1.7 2 0 0 2 2 2 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH SAC3_GANP PF03399.16 CAR29816.1 - 1.4e-17 64.0 6.1 1.5e-15 57.4 6.1 2.1 1 1 0 1 1 1 1 SAC3/GANP family COX5A PF02284.16 CAR29816.1 - 0.06 13.4 0.1 0.16 12.0 0.1 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va PCI PF01399.27 CAR29816.1 - 0.4 11.2 3.9 0.47 11.0 0.7 2.5 1 1 1 2 2 2 0 PCI domain Scramblase PF03803.15 CAR29817.1 - 8.3e-68 228.0 0.1 2.3e-33 115.3 0.0 2.0 2 0 0 2 2 2 2 Scramblase Sod_Fe_C PF02777.18 CAR29818.1 - 1.7e-15 57.0 1.6 9.3e-13 48.2 1.6 2.3 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain ESCRT-II PF05871.12 CAR29819.1 - 2.6e-46 157.4 0.2 3.1e-46 157.1 0.2 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Alpha-2-MRAP_N PF06400.11 CAR29820.1 - 0.019 15.0 7.0 0.13 12.3 1.1 2.7 2 1 1 3 3 3 0 Alpha-2-macroglobulin RAP, N-terminal domain DUF489 PF04356.12 CAR29820.1 - 0.15 12.1 5.8 0.38 10.7 1.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF489) DDE_Tnp_IS66 PF03050.14 CAR29820.1 - 0.35 10.3 10.4 0.07 12.6 1.8 2.0 1 1 1 2 2 2 0 Transposase IS66 family SLATT_1 PF18181.1 CAR29820.1 - 0.47 10.4 2.9 0.98 9.4 0.4 2.4 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 1 DUF3496 PF12001.8 CAR29820.1 - 2.3 8.6 12.7 0.9 9.9 3.9 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF3496) CTP_synth_N PF06418.14 CAR29821.1 - 4.2e-123 409.8 0.1 5.5e-123 409.5 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CAR29821.1 - 9.3e-59 198.4 0.0 1.4e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DUF5335 PF17269.2 CAR29821.1 - 0.001 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5335) Peptidase_C26 PF07722.13 CAR29821.1 - 0.0021 17.8 0.1 0.028 14.2 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 C_Hendra PF16821.5 CAR29821.1 - 0.047 13.6 0.6 0.1 12.5 0.6 1.5 1 0 0 1 1 1 0 C protein from hendra and measles viruses DJ-1_PfpI PF01965.24 CAR29821.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Sod_Cu PF00080.20 CAR29822.1 - 1.2e-45 155.2 4.4 1.5e-45 154.9 4.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ER_lumen_recept PF00810.18 CAR29823.1 - 3e-49 167.6 13.9 3e-49 167.6 13.9 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor Proteasome PF00227.26 CAR29824.1 - 2.5e-35 121.7 0.1 1.5e-34 119.2 0.1 1.8 1 1 0 1 1 1 1 Proteasome subunit Gemini_AL3 PF01407.17 CAR29824.1 - 0.035 14.0 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Geminivirus AL3 protein Transp_cyt_pur PF02133.15 CAR29825.1 - 1.1e-151 505.6 35.5 1.2e-151 505.4 35.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3948 PF13134.6 CAR29825.1 - 3.1 7.5 5.5 0.3 10.8 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) RP-C_C PF11800.8 CAR29826.1 - 0.17 12.0 1.8 0.23 11.5 1.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region BUD22 PF09073.10 CAR29826.1 - 0.2 10.9 18.6 0.28 10.5 18.6 1.2 1 0 0 1 1 1 0 BUD22 Orf78 PF06024.12 CAR29826.1 - 0.51 10.7 2.5 3 8.2 0.0 2.3 2 0 0 2 2 2 0 Orf78 (ac78) Presenilin PF01080.17 CAR29826.1 - 0.62 8.8 4.5 0.65 8.7 4.5 1.2 1 0 0 1 1 1 0 Presenilin HGTP_anticodon2 PF12745.7 CAR29826.1 - 0.8 9.2 7.6 2 7.8 7.6 1.6 1 1 0 1 1 1 0 Anticodon binding domain of tRNAs Hid1 PF12722.7 CAR29826.1 - 1.1 7.3 3.6 1.2 7.2 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CobT PF06213.12 CAR29826.1 - 1.4 8.3 20.9 0.12 11.7 14.0 2.0 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 CAR29826.1 - 2.1 6.3 28.9 0.11 10.6 19.3 2.0 2 0 0 2 2 2 0 DNA polymerase phi Peptidase_M16_C PF05193.21 CAR29827.1 - 7.3e-23 81.5 0.0 1.6e-22 80.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CAR29827.1 - 2e-21 76.5 0.0 4.2e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PPP4R2 PF09184.11 CAR29828.1 - 2.3e-58 198.1 31.4 2.3e-58 198.1 31.4 2.5 1 1 1 2 2 2 1 PPP4R2 Nop14 PF04147.12 CAR29828.1 - 0.017 13.4 29.8 0.024 12.9 29.8 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CAR29828.1 - 0.069 11.4 22.6 0.1 10.8 22.6 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 CAR29828.1 - 1 9.8 5.9 3.3 8.1 5.8 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 CAR29828.1 - 1.9 8.3 13.9 1 9.1 11.7 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 CAR29828.1 - 3.7 7.7 10.1 8 6.6 10.1 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2151 PF10221.9 CAR29828.1 - 5.2 5.5 10.6 6.8 5.2 9.8 1.5 2 0 0 2 2 2 0 Cell cycle and development regulator Ribosomal_S7 PF00177.21 CAR29829.1 - 2.1e-36 124.8 0.1 3.1e-36 124.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MA3 PF02847.17 CAR29829.1 - 0.064 13.2 0.2 4 7.4 0.0 2.4 2 0 0 2 2 2 0 MA3 domain EF-hand_4 PF12763.7 CAR29830.1 - 1.8e-27 95.3 0.0 4.9e-08 32.9 0.0 3.6 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CAR29830.1 - 8.4e-11 40.6 0.0 0.0072 15.8 0.0 3.9 3 0 0 3 3 3 2 EF hand UBA PF00627.31 CAR29830.1 - 1.5e-10 40.7 0.1 1.5e-10 40.7 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_6 PF13405.6 CAR29830.1 - 1.1e-08 34.4 0.0 0.33 11.0 0.0 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 CAR29830.1 - 4.4e-08 33.5 0.0 0.15 12.6 0.0 4.0 3 0 0 3 3 3 2 EF-hand domain pair UBA_4 PF14555.6 CAR29830.1 - 0.00074 19.3 0.1 0.0019 18.0 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain Med9 PF07544.13 CAR29830.1 - 0.0015 18.6 3.2 0.0015 18.6 3.2 4.7 2 1 3 5 5 4 1 RNA polymerase II transcription mediator complex subunit 9 EF-hand_5 PF13202.6 CAR29830.1 - 0.0072 15.8 0.0 9.4 5.9 0.0 3.3 3 0 0 3 3 3 1 EF hand DUF3584 PF12128.8 CAR29830.1 - 0.054 11.0 47.4 0.081 10.4 47.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2420 PF10336.9 CAR29830.1 - 0.23 11.5 3.4 0.64 10.1 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) TPR_MLP1_2 PF07926.12 CAR29830.1 - 0.43 10.7 61.0 0.32 11.1 26.3 3.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 CAR29830.1 - 0.5 10.9 58.0 0.42 11.1 16.5 3.5 1 1 2 3 3 3 0 Apg6 coiled-coil region DUF3552 PF12072.8 CAR29830.1 - 1.2 8.5 45.6 0.051 13.0 14.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Tropomyosin_1 PF12718.7 CAR29830.1 - 1.5 8.9 48.7 0.14 12.3 22.7 3.1 1 1 2 3 3 3 0 Tropomyosin like Spc7 PF08317.11 CAR29830.1 - 1.8 7.4 52.9 1 8.2 14.6 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CAR29830.1 - 1.9 8.5 47.9 0.79 9.7 26.6 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM76 PF16046.5 CAR29830.1 - 2.2 7.5 36.3 0.17 11.2 5.2 2.4 2 0 0 2 2 2 0 FAM76 protein Jnk-SapK_ap_N PF09744.9 CAR29830.1 - 4.6 7.5 53.7 0.88 9.8 19.7 3.4 1 1 1 2 2 1 0 JNK_SAPK-associated protein-1 Nnf1 PF03980.14 CAR29831.1 - 7.7e-30 103.5 7.9 1.2e-29 102.9 7.9 1.3 1 0 0 1 1 1 1 Nnf1 DUF4618 PF15397.6 CAR29831.1 - 0.013 15.0 3.0 0.013 15.0 3.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4618) Herpes_BLRF2 PF05812.12 CAR29831.1 - 0.014 15.5 1.5 0.034 14.3 0.3 2.1 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Prominin PF05478.11 CAR29831.1 - 0.014 13.4 1.0 0.017 13.1 1.0 1.1 1 0 0 1 1 1 0 Prominin bZIP_1 PF00170.21 CAR29831.1 - 0.015 15.4 2.1 0.015 15.4 2.1 1.9 2 0 0 2 2 2 0 bZIP transcription factor FlaC_arch PF05377.11 CAR29831.1 - 0.031 14.7 2.0 0.047 14.1 0.5 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Ta0938 PF11494.8 CAR29831.1 - 0.089 13.1 0.1 0.22 11.8 0.1 1.7 1 1 0 1 1 1 0 Ta0938 FapA PF03961.13 CAR29831.1 - 0.17 10.5 3.8 0.23 10.0 3.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMF_DNA_bd PF12329.8 CAR29831.1 - 0.5 10.4 7.1 0.12 12.4 1.2 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding E2F_CC-MB PF16421.5 CAR29831.1 - 0.79 10.1 4.6 23 5.5 0.1 2.5 2 0 0 2 2 2 0 E2F transcription factor CC-MB domain CMD PF02627.20 CAR29832.1 - 7.3e-07 29.2 0.0 2.8e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Myotub-related PF06602.14 CAR29833.1 - 2.6e-141 470.6 0.6 3.4e-141 470.3 0.6 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 CAR29833.1 - 0.002 18.0 0.0 0.0069 16.3 0.0 1.9 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.6 CAR29833.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PH_BEACH PF14844.6 CAR29833.1 - 0.045 13.8 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Y_phosphatase PF00102.27 CAR29833.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase HTH_29 PF13551.6 CAR29833.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix Yippee-Mis18 PF03226.14 CAR29834.1 - 8.3e-13 48.5 4.0 1.3e-12 47.9 4.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SNAP PF14938.6 CAR29835.1 - 4.2e-109 364.3 9.1 4.8e-109 364.2 9.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP Foie-gras_1 PF11817.8 CAR29835.1 - 3.2e-05 23.7 0.7 5.8e-05 22.8 0.3 1.7 1 1 1 2 2 2 1 Foie gras liver health family 1 TPR_7 PF13176.6 CAR29835.1 - 0.0046 16.9 2.5 0.36 10.9 0.0 4.1 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CAR29835.1 - 0.0049 17.1 4.6 0.055 13.8 0.0 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CAR29835.1 - 0.0058 16.7 7.8 6.2 7.2 0.9 5.2 3 3 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CAR29835.1 - 0.011 16.4 7.8 15 6.5 0.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAR29835.1 - 0.057 13.7 10.2 0.81 10.1 1.0 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CAR29835.1 - 0.085 12.7 9.5 2.4 8.1 0.2 4.9 4 2 1 5 5 5 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 CAR29835.1 - 0.16 11.0 3.9 0.58 9.2 0.6 2.3 1 1 0 2 2 2 0 Spatacsin C-terminus NSF PF02071.20 CAR29835.1 - 2.3 9.4 15.9 9.9 7.5 0.2 6.4 7 0 0 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat DUF2225 PF09986.9 CAR29835.1 - 3.3 7.4 9.2 6.3 6.5 1.5 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_11 PF13414.6 CAR29835.1 - 8.8 6.1 8.8 8.6 6.1 0.1 4.3 4 1 1 5 5 5 0 TPR repeat CPSase_L_D2 PF02786.17 CAR29836.1 - 6.1e-108 359.2 0.0 4.3e-84 281.2 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 CAR29836.1 - 8.3e-38 129.5 0.8 1.7e-37 128.5 0.8 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CAR29836.1 - 7.3e-19 68.0 0.0 2.4e-08 33.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CAR29836.1 - 6.6e-16 58.4 0.0 8.7e-07 28.7 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CAR29836.1 - 7.6e-15 54.8 0.0 4.6e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.22 CAR29836.1 - 0.0032 17.6 0.0 0.016 15.4 0.0 2.3 2 0 0 2 2 2 1 MGS-like domain ATP-grasp_5 PF13549.6 CAR29836.1 - 0.0054 16.2 0.1 0.77 9.2 0.1 2.7 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 CAR29836.1 - 0.036 13.8 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Epimerase PF01370.21 CAR29836.1 - 0.059 12.8 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_5 PF07994.12 CAR29837.1 - 1.5e-143 478.0 0.0 1.8e-143 477.8 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CAR29837.1 - 1.1e-43 147.8 0.8 1.1e-43 147.8 0.8 1.9 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase peroxidase PF00141.23 CAR29838.1 - 1.1e-41 143.0 0.0 1.8e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Vps35 PF03635.17 CAR29839.1 - 1.8e-280 932.6 28.8 2.1e-280 932.4 28.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Laminin_I PF06008.14 CAR29839.1 - 0.068 12.9 2.8 0.35 10.5 0.0 2.9 3 0 0 3 3 3 0 Laminin Domain I Phage_int_SAM_5 PF13102.6 CAR29839.1 - 0.12 12.7 2.2 14 6.1 0.6 2.9 2 0 0 2 2 2 0 Phage integrase SAM-like domain 6PF2K PF01591.18 CAR29840.1 - 1.2e-85 286.3 0.3 1.6e-85 286.0 0.3 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CAR29840.1 - 1.4e-37 129.3 0.0 2.1e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CAR29840.1 - 1.6e-05 25.1 0.0 4.7e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 CAR29840.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Diphthami_syn_2 PF01902.17 CAR29840.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Diphthamide synthase Integrase_1 PF12835.7 CAR29840.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Integrase AAA_17 PF13207.6 CAR29840.1 - 0.15 12.5 0.0 0.46 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Peptidase_S64 PF08192.11 CAR29841.1 - 1.1e-278 926.5 0.2 1.3e-278 926.3 0.2 1.0 1 0 0 1 1 1 1 Peptidase family S64 DUF4834 PF16118.5 CAR29841.1 - 5.7 8.0 5.5 48 5.0 2.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4834) zf-RING_11 PF17123.5 CAR29842.1 - 0.0094 15.7 2.0 0.021 14.5 2.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger PHD PF00628.29 CAR29842.1 - 0.17 11.8 7.8 1.3 9.0 6.3 2.7 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.6 CAR29842.1 - 0.59 10.5 11.3 0.053 13.9 5.3 2.3 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.25 CAR29842.1 - 0.69 9.8 7.7 0.58 10.1 4.8 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PIR PF00399.19 CAR29843.1 - 2.5e-07 30.1 22.0 8.2e-05 22.1 7.6 3.3 2 0 0 2 2 2 2 Yeast PIR protein repeat PIR PF00399.19 CAR29844.1 - 7.8e-38 127.2 94.2 5.5e-08 32.2 2.6 8.4 7 0 0 7 7 7 7 Yeast PIR protein repeat PIR PF00399.19 CAR29845.1 - 8.8e-60 197.1 131.8 1e-07 31.3 5.9 9.7 9 0 0 9 9 9 9 Yeast PIR protein repeat Trypan_PARP PF05887.11 CAR29845.1 - 8.7 6.3 11.5 9.4 6.2 1.4 2.7 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF1989 PF09347.10 CAR29846.1 - 7.6e-60 201.4 0.0 1e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) MASE2 PF05230.11 CAR29847.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 MASE2 domain Tic110 PF16940.5 CAR29847.1 - 0.14 10.6 0.0 0.19 10.1 0.0 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter DnaJ PF00226.31 CAR29848.1 - 4.2e-20 71.6 1.0 1.4e-19 70.0 1.0 2.0 1 0 0 1 1 1 1 DnaJ domain AAA_21 PF13304.6 CAR29848.1 - 0.39 10.5 7.7 0.72 9.6 6.9 1.8 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PigN PF04987.14 CAR29849.1 - 7.7e-126 420.6 45.5 1e-125 420.2 45.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CAR29849.1 - 2.7e-13 50.2 0.8 5.1e-10 39.5 0.2 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CAR29849.1 - 3e-10 40.0 0.1 5.1e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CAR29849.1 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily CENP-M PF11111.8 CAR29849.1 - 0.24 10.6 0.6 1 8.6 0.1 2.0 2 0 0 2 2 2 0 Centromere protein M (CENP-M) MFS_1 PF07690.16 CAR29850.1 - 4.3e-17 62.1 17.6 4.3e-17 62.1 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CCB2_CCB4 PF11152.8 CAR29850.1 - 0.024 13.9 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 Pkinase PF00069.25 CAR29851.1 - 7.7e-71 238.5 0.3 1.3e-70 237.8 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29851.1 - 4.3e-38 131.1 0.0 6.6e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR29851.1 - 0.00081 18.8 0.0 0.0019 17.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CAR29851.1 - 0.1 11.6 0.0 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain APH PF01636.23 CAR29851.1 - 0.16 11.8 0.9 0.37 10.7 0.0 1.9 2 1 0 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 CAR29851.1 - 0.53 9.9 3.8 0.86 9.2 0.0 2.7 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Presenilin PF01080.17 CAR29851.1 - 2.9 6.6 4.8 4.1 6.1 4.8 1.1 1 0 0 1 1 1 0 Presenilin L51_S25_CI-B8 PF05047.16 CAR29852.1 - 3.5e-12 46.1 0.1 8.4e-12 44.8 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pkinase PF00069.25 CAR29853.1 - 2.3e-39 135.4 0.0 1e-38 133.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29853.1 - 2.2e-17 63.2 0.0 3.8e-17 62.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L14 PF00238.19 CAR29854.1 - 2.3e-41 140.7 2.0 2.5e-41 140.6 2.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.25 CAR29855.1 - 2.3e-39 135.4 0.0 2.4e-24 86.1 0.5 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29855.1 - 1.2e-18 67.4 0.0 1.7e-14 53.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CAR29855.1 - 0.026 13.8 0.0 6 6.1 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CAR29855.1 - 0.065 12.6 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UcrQ PF02939.16 CAR29856.1 - 9.9e-32 108.7 0.7 1.2e-31 108.5 0.7 1.1 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 CAR29856.1 - 0.00089 19.6 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 polyprenyl_synt PF00348.17 CAR29857.1 - 5.3e-95 317.3 0.0 6.5e-95 317.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ebp2 PF05890.12 CAR29858.1 - 3.7e-87 292.3 25.8 3.7e-87 292.3 25.8 3.0 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 GTP_EFTU PF00009.27 CAR29859.1 - 8e-35 120.1 0.0 1.2e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CAR29859.1 - 4.9e-17 61.7 0.0 9.6e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CAR29859.1 - 2.3e-16 59.7 0.0 4.1e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 CAR29859.1 - 2.2e-09 37.6 0.0 4.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CAR29859.1 - 1.2e-05 25.3 0.0 3.9e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFTUD2 PF16004.5 CAR29859.1 - 3e-05 24.6 12.0 0.00029 21.4 12.0 2.1 1 1 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus MMR_HSR1 PF01926.23 CAR29859.1 - 0.001 19.2 0.0 0.0027 17.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Mersacidin PF16934.5 CAR29859.1 - 0.19 11.5 0.7 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) SRPRB PF09439.10 CAR29859.1 - 0.2 11.1 0.0 0.87 9.0 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AA_permease PF00324.21 CAR29860.1 - 4.5e-73 246.5 37.8 5.6e-73 246.2 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CAR29860.1 - 1.7e-38 132.6 40.7 2.3e-38 132.1 40.7 1.2 1 0 0 1 1 1 1 Amino acid permease MMPL PF03176.15 CAR29860.1 - 4.9 6.0 8.2 0.24 10.3 0.4 2.5 3 0 0 3 3 3 0 MMPL family Zip PF02535.22 CAR29861.1 - 1.7e-22 80.1 11.2 3e-21 76.0 11.2 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1761 PF08570.10 CAR29861.1 - 0.021 15.1 1.2 0.052 13.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) Longin_2 PF18639.1 CAR29862.1 - 3.4e-66 222.2 0.0 7.3e-66 221.1 0.0 1.6 1 0 0 1 1 1 1 Yeast longin domain CRAL_TRIO PF00650.20 CAR29862.1 - 0.0056 16.4 0.0 0.36 10.5 0.0 2.4 2 0 0 2 2 2 2 CRAL/TRIO domain SRI PF08236.11 CAR29863.1 - 6.9e-25 87.0 2.7 6.9e-25 87.0 2.7 3.2 2 1 1 3 3 3 1 SRI (Set2 Rpb1 interacting) domain WW_1 PF18507.1 CAR29863.1 - 4.6e-19 67.8 2.6 1.1e-18 66.5 2.6 1.7 1 0 0 1 1 1 1 WW domain SET PF00856.28 CAR29863.1 - 2.9e-16 60.3 0.1 2.9e-16 60.3 0.1 3.7 3 2 0 3 3 3 1 SET domain AWS PF17907.1 CAR29863.1 - 8.1e-15 54.6 10.4 8.1e-15 54.6 10.4 2.0 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 CAR29863.1 - 0.014 15.4 0.3 0.014 15.4 0.3 2.7 2 0 0 2 2 2 0 TFIIS helical bundle-like domain APG6_N PF17675.1 CAR29863.1 - 0.95 10.0 25.2 5.4 7.5 0.1 3.4 3 0 0 3 3 3 0 Apg6 coiled-coil region LMBR1 PF04791.16 CAR29863.1 - 9 5.1 8.6 14 4.5 8.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein STE3 PF02076.15 CAR29865.1 - 1.9e-86 289.9 18.3 2.3e-86 289.6 18.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor Mit_proteolip PF08039.11 CAR29865.1 - 0.088 13.3 1.8 0.13 12.7 0.0 2.3 2 1 0 2 2 2 0 Mitochondrial proteolipid Peptidase_M20 PF01546.28 CAR29866.1 - 2.2e-39 135.3 0.0 4.6e-39 134.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR29866.1 - 1.9e-13 50.3 0.0 4.1e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CAR29866.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Rep_fac-A_3 PF08661.11 CAR29867.1 - 4.6e-25 88.0 0.0 5.1e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 P22_CoatProtein PF11651.8 CAR29867.1 - 0.024 13.3 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 P22 coat protein - gene protein 5 2-Hacid_dh_C PF02826.19 CAR29868.1 - 8.4e-40 136.0 0.0 3e-39 134.2 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAR29868.1 - 8.8e-18 64.3 0.1 1.2e-17 63.8 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.20 CAR29868.1 - 0.014 15.4 0.5 0.47 10.5 0.0 2.7 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase KRE9 PF05390.11 CAR29869.1 - 2.8e-41 140.4 14.4 5.6e-41 139.4 14.4 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CAR29869.1 - 8e-12 45.8 0.4 8e-12 45.8 0.4 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GBS_Bsp-like PF08481.10 CAR29869.1 - 0.022 14.9 0.7 0.07 13.2 0.7 2.0 1 1 0 1 1 1 0 GBS Bsp-like repeat Big_7 PF17957.1 CAR29869.1 - 0.046 14.5 0.7 0.046 14.5 0.7 3.4 2 2 0 2 2 2 0 Bacterial Ig domain Ntox37 PF15535.6 CAR29869.1 - 0.05 14.0 0.9 0.05 14.0 0.9 2.2 2 1 0 2 2 2 0 Bacterial toxin 37 HECT PF00632.25 CAR29870.1 - 2e-92 310.0 0.0 2.7e-92 309.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CAR29870.1 - 4.1e-33 113.2 22.2 4.2e-12 45.9 1.3 4.1 4 0 0 4 4 4 3 WW domain C2 PF00168.30 CAR29870.1 - 1.7e-19 70.0 0.1 4.8e-19 68.5 0.1 1.7 1 0 0 1 1 1 1 C2 domain PUF PF00806.19 CAR29872.1 - 2e-55 181.4 31.0 9.6e-08 31.3 1.6 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ribosomal_S8e PF01201.22 CAR29873.1 - 1.6e-44 151.4 0.4 2.3e-44 150.9 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.12 CAR29873.1 - 0.12 12.2 0.1 0.12 12.2 0.1 1.6 2 0 0 2 2 2 0 Homeo-prospero domain Red1 PF07964.11 CAR29873.1 - 0.61 8.3 12.4 0.75 8.0 12.4 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Pannexin_like PF12534.8 CAR29873.1 - 4.2 6.4 5.6 5.9 5.9 5.6 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Sas10_Utp3 PF04000.15 CAR29874.1 - 4.2e-11 43.3 2.2 8.3e-11 42.4 1.1 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Vfa1 PF08432.10 CAR29875.1 - 4.1e-39 134.8 0.5 5.1e-39 134.5 0.5 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Tsc35 PF15079.6 CAR29875.1 - 0.046 13.3 2.8 0.067 12.8 2.8 1.3 1 0 0 1 1 1 0 Testis-specific protein 35 DUF501 PF04417.12 CAR29875.1 - 0.49 10.2 2.1 0.81 9.5 1.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF501) CRA PF06589.11 CAR29875.1 - 0.86 9.7 4.5 0.33 11.1 1.8 1.6 1 1 1 2 2 2 0 Circumsporozoite-related antigen (CRA) Pkinase PF00069.25 CAR29876.1 - 1.4e-51 175.4 0.0 2.4e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29876.1 - 1.2e-23 83.8 0.0 4.3e-23 81.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR29876.1 - 0.00014 21.3 0.0 0.00043 19.7 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CAR29876.1 - 0.0014 17.5 0.0 0.0027 16.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF3543 PF12063.8 CAR29877.1 - 4.1e-85 285.2 5.9 1e-84 283.8 5.9 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 CAR29877.1 - 1.1e-58 198.7 0.0 1.9e-58 197.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29877.1 - 4e-43 147.6 0.0 6.7e-43 146.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEPN_AbiU2 PF18734.1 CAR29877.1 - 0.013 15.0 0.9 0.27 10.7 0.1 2.4 2 0 0 2 2 2 0 AbiU2 Kinase-like PF14531.6 CAR29877.1 - 0.015 14.7 0.1 0.19 11.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like ArfGap PF01412.18 CAR29878.1 - 7.5e-30 103.4 0.0 7.5e-30 103.4 0.0 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Transformer PF06495.11 CAR29878.1 - 0.028 14.5 0.5 0.028 14.5 0.5 2.5 3 0 0 3 3 3 0 Fruit fly transformer protein HSP70 PF00012.20 CAR29878.1 - 0.56 8.3 12.1 0.76 7.9 12.1 1.1 1 0 0 1 1 1 0 Hsp70 protein SMYLE_N PF18615.1 CAR29878.1 - 2.8 7.4 14.0 5.7 6.4 14.0 1.4 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Mnd1 PF03962.15 CAR29879.1 - 9e-28 96.4 2.1 9e-28 96.4 2.1 2.0 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 CAR29879.1 - 9e-05 22.5 1.5 9e-05 22.5 1.5 2.8 4 1 1 5 5 5 1 Leucine zipper with capping helix domain LRR_RI_capping PF18779.1 CAR29879.1 - 0.07 12.8 0.5 0.17 11.5 0.5 1.7 1 0 0 1 1 1 0 Capping Ribonuclease inhibitor Leucine Rich Repeat CaM_binding PF07839.11 CAR29879.1 - 0.2 12.4 5.6 0.38 11.5 5.6 1.5 1 0 0 1 1 1 0 Plant calmodulin-binding domain zf-C2H2 PF00096.26 CAR29880.1 - 3.9e-12 45.9 13.9 8.7e-06 25.9 3.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR29880.1 - 8.2e-08 32.5 14.4 0.00043 20.9 1.2 2.9 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CAR29880.1 - 7.3e-05 22.9 16.9 0.0025 18.1 1.3 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CAR29880.1 - 0.017 15.5 15.2 0.4 11.1 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Actin_micro PF17003.5 CAR29880.1 - 0.021 14.0 3.4 0.061 12.5 3.4 1.8 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_6 PF13912.6 CAR29880.1 - 0.12 12.4 16.7 0.033 14.2 3.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR29880.1 - 0.14 12.7 21.3 0.058 13.8 6.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2HC_2 PF13913.6 CAR29880.1 - 0.81 9.7 8.9 4.6 7.3 2.3 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type EMC3_TMCO1 PF01956.16 CAR29880.1 - 1.1 9.0 4.0 1.6 8.4 4.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4407 PF14362.6 CAR29880.1 - 1.1 8.6 4.5 1.5 8.1 3.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GNAT_acetyltr_2 PF13718.6 CAR29880.1 - 1.4 8.2 5.4 0.24 10.8 1.5 1.6 2 0 0 2 2 2 0 GNAT acetyltransferase 2 zf-Di19 PF05605.12 CAR29880.1 - 3 8.2 14.4 0.19 12.0 8.3 2.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CAR29880.1 - 4.2 7.2 14.7 3 7.7 1.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 CAR29880.1 - 7 7.3 13.0 19 6.0 0.7 3.9 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-DBF PF07535.12 CAR29880.1 - 7.7 6.7 10.9 8.1 6.6 1.4 3.6 3 0 0 3 3 3 0 DBF zinc finger Cys_Met_Meta_PP PF01053.20 CAR29881.1 - 2.2e-120 401.7 0.0 2.6e-120 401.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CAR29881.1 - 0.0017 16.9 0.0 0.0025 16.4 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase 2-Hacid_dh_C PF02826.19 CAR29882.1 - 4.2e-28 97.9 0.0 6e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAR29882.1 - 0.0002 21.0 0.0 0.00038 20.1 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain COX5B PF01215.19 CAR29883.1 - 4.6e-64 213.9 0.0 5.4e-64 213.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Ribosomal_S26e PF01283.19 CAR29884.1 - 2.6e-50 169.4 10.8 3e-50 169.2 10.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e PLL PF18587.1 CAR29884.1 - 0.14 12.3 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 PTX/LNS-Like (PLL) domain WD40 PF00400.32 CAR29885.1 - 2.1e-16 60.0 2.3 0.00099 19.9 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF5452 PF17533.2 CAR29885.1 - 0.00089 19.4 0.5 0.0033 17.5 0.5 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5452) ANAPC4_WD40 PF12894.7 CAR29885.1 - 0.002 18.4 0.1 20 5.6 0.0 4.6 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR29885.1 - 0.056 12.4 0.3 18 4.1 0.0 3.1 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein EFTUD2 PF16004.5 CAR29885.1 - 0.47 11.0 5.2 2.1 8.9 4.8 2.3 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus SPATA3 PF15662.5 CAR29885.1 - 4.3 7.9 16.2 7.2 7.2 16.2 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 3 family COX6A PF02046.15 CAR29886.1 - 3.1e-39 133.9 2.6 3.5e-39 133.8 2.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa MT-A70 PF05063.14 CAR29887.1 - 5.1e-56 189.3 0.5 8.3e-56 188.6 0.1 1.5 2 0 0 2 2 2 1 MT-A70 Glyco_hydro_30 PF02055.16 CAR29887.1 - 0.019 13.9 0.0 0.062 12.3 0.0 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 30 TIM-barrel domain Hist_deacetyl PF00850.19 CAR29888.1 - 4.8e-83 279.1 0.0 6e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Zn_clus PF00172.18 CAR29889.1 - 1.2e-09 38.1 10.6 1.2e-09 38.1 10.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CAR29889.1 - 6.5e-06 25.2 1.1 1e-05 24.6 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT_EZ PF13513.6 CAR29890.1 - 5.6e-27 93.8 26.0 0.0024 18.4 0.0 15.6 15 2 4 19 19 18 6 HEAT-like repeat HEAT PF02985.22 CAR29890.1 - 1.1e-24 84.3 18.4 0.026 14.7 0.0 17.1 21 0 0 21 21 20 5 HEAT repeat HEAT_2 PF13646.6 CAR29890.1 - 2.5e-24 85.5 13.8 6.6e-05 23.2 0.4 10.9 7 2 5 12 12 12 6 HEAT repeats Gcn1_N PF12074.8 CAR29890.1 - 6.1e-21 75.1 2.0 7.3e-10 38.7 0.1 4.7 4 0 0 4 4 4 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Vac14_Fab1_bd PF12755.7 CAR29890.1 - 3.7e-14 53.1 0.0 0.48 11.0 0.0 9.9 7 2 2 10 10 9 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CAR29890.1 - 6e-12 45.6 0.0 0.0057 16.3 0.0 7.1 4 1 5 9 9 9 3 CLASP N terminal Cnd1 PF12717.7 CAR29890.1 - 1.3e-11 44.8 17.7 0.2 11.7 0.9 11.3 8 3 3 11 11 11 3 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 CAR29890.1 - 0.0018 18.2 7.2 67 3.3 0.0 8.6 9 2 1 10 10 10 0 Domain of unknown function (DUF3385) Vitellogenin_N PF01347.22 CAR29890.1 - 0.041 12.3 1.3 4.4 5.6 0.0 3.6 3 0 0 3 3 3 0 Lipoprotein amino terminal region UNC45-central PF11701.8 CAR29890.1 - 0.046 13.7 0.6 11 6.0 0.0 4.5 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central rhaM PF05336.13 CAR29890.1 - 0.054 13.6 0.3 1.5 8.9 1.1 2.5 2 0 0 2 2 2 0 L-rhamnose mutarotase D-ser_dehydrat PF14031.6 CAR29891.1 - 6.3e-22 78.1 0.1 4.1e-20 72.2 0.0 2.7 3 0 0 3 3 3 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CAR29891.1 - 9.5e-09 35.2 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Kelch_4 PF13418.6 CAR29892.1 - 1.4e-11 44.2 3.4 0.001 19.0 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CAR29892.1 - 2.2e-11 43.6 0.2 2e-05 24.7 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CAR29892.1 - 1.1e-08 35.1 0.0 0.001 19.3 0.0 4.5 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CAR29892.1 - 1.9e-08 33.7 0.5 0.11 12.1 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CAR29892.1 - 1.4e-06 28.0 0.5 0.0088 16.0 0.1 4.9 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.6 CAR29892.1 - 0.00052 19.9 0.0 0.007 16.3 0.0 2.6 2 0 0 2 2 2 1 Kelch motif SUIM_assoc PF16619.5 CAR29892.1 - 0.0026 17.8 1.7 0.0026 17.8 1.7 2.4 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Yip1 PF04893.17 CAR29893.1 - 7.6e-09 35.5 8.7 8.6e-09 35.3 8.7 1.2 1 0 0 1 1 1 1 Yip1 domain Metallophos PF00149.28 CAR29894.1 - 2.7e-40 139.1 0.1 3.6e-40 138.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CAR29894.1 - 1.1e-22 80.2 1.5 1.8e-22 79.5 0.5 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain EMP24_GP25L PF01105.24 CAR29895.1 - 8e-46 156.3 0.0 9.1e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF5643 PF18705.1 CAR29895.1 - 0.023 14.7 0.2 0.034 14.1 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5643) Orbi_VP5 PF00901.17 CAR29895.1 - 0.15 10.4 0.0 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Vps62 PF06101.11 CAR29897.1 - 1.1e-05 24.0 2.1 8.3e-05 21.1 1.4 2.2 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 NDC10_II PF16787.5 CAR29898.1 - 2.3e-91 306.1 0.0 9.8e-91 304.1 0.0 1.9 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CAR29898.1 - 1.1e-16 61.0 0.1 4.4e-16 59.0 0.1 2.2 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF4211 PF13926.6 CAR29898.1 - 0.017 15.2 0.7 6.9 6.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) Herpes_UL6 PF01763.16 CAR29898.1 - 0.053 12.1 0.5 1.3 7.5 0.2 2.2 2 0 0 2 2 2 0 Herpesvirus UL6 like Shugoshin_N PF07558.11 CAR29898.1 - 0.15 12.0 0.3 0.36 10.7 0.3 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region MFS_1 PF07690.16 CAR29899.1 - 3.6e-34 118.3 31.0 3.6e-34 118.3 31.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR29899.1 - 9e-12 44.6 25.8 1.4e-11 44.0 25.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Utp11 PF03998.13 CAR29905.1 - 3e-69 233.7 36.2 3.5e-69 233.5 36.2 1.0 1 0 0 1 1 1 1 Utp11 protein Peptidase_A22B PF04258.13 CAR29906.1 - 1e-50 172.8 3.9 1.6e-50 172.2 3.9 1.2 1 0 0 1 1 1 1 Signal peptide peptidase RRM_1 PF00076.22 CAR29907.1 - 6.8e-15 54.7 0.0 1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2-Hacid_dh_C PF02826.19 CAR29908.1 - 8.5e-40 136.0 0.0 6.5e-39 133.1 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CAR29908.1 - 8.9e-18 64.2 0.1 1.1e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.20 CAR29908.1 - 0.063 13.3 0.1 1.9 8.5 0.0 2.6 2 2 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PI3_PI4_kinase PF00454.27 CAR29909.1 - 5.6e-43 147.6 0.0 1.6e-40 139.5 0.0 2.8 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CAR29909.1 - 7.9e-25 87.3 0.0 1.8e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) UQ_con PF00179.26 CAR29910.1 - 1.2e-34 119.0 0.0 1.4e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CAR29910.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B SPG4 PF17325.2 CAR29911.1 - 1.1e-36 126.2 6.5 7.9e-35 120.3 6.5 2.0 1 1 0 1 1 1 1 Stationary phase protein 4 PaaB PF06243.11 CAR29911.1 - 0.0024 18.1 0.0 0.0028 17.9 0.0 1.3 1 1 0 1 1 1 1 Phenylacetic acid degradation B CytoC_RC PF02276.18 CAR29911.1 - 0.021 14.2 0.2 0.024 14.0 0.2 1.0 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Pyocin_S PF06958.12 CAR29911.1 - 0.054 14.0 0.7 0.071 13.6 0.7 1.1 1 0 0 1 1 1 0 S-type Pyocin Pam16 PF03656.13 CAR29911.1 - 0.066 13.2 0.1 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 Pam16 TPP_enzyme_N PF02776.18 CAR29912.1 - 7.5e-57 191.7 0.2 2.4e-56 190.0 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CAR29912.1 - 5.6e-49 165.8 0.0 7.1e-47 159.0 0.0 2.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR29912.1 - 1.7e-36 125.0 0.5 4.6e-36 123.6 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Indigoidine_A PF04227.12 CAR29912.1 - 0.039 13.3 0.0 30 3.9 0.0 3.2 2 1 1 3 3 3 0 Indigoidine synthase A like protein POR_N PF01855.19 CAR29912.1 - 0.052 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Myosin_head PF00063.21 CAR29913.1 - 2.7e-234 779.4 4.8 3.4e-234 779.1 4.8 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CAR29913.1 - 1.2e-48 165.3 0.6 2e-48 164.6 0.6 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 CAR29913.1 - 6.7e-10 38.4 0.0 1.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR29913.1 - 3.4e-06 26.8 0.0 7.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR29913.1 - 0.00013 21.5 0.0 0.00045 19.8 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 CAR29913.1 - 0.023 15.1 0.0 0.081 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CAR29913.1 - 0.049 13.9 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hpr_kinase_C PF07475.12 CAR29913.1 - 0.055 13.0 0.1 9.1 5.8 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.26 CAR29913.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.12 CAR29913.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IQ PF00612.27 CAR29913.1 - 7.7 6.6 10.9 15 5.7 0.8 2.7 1 1 1 2 2 2 0 IQ calmodulin-binding motif She2p PF11435.8 CAR29914.1 - 3.9e-93 310.7 6.7 5.2e-93 310.3 6.7 1.1 1 0 0 1 1 1 1 RNA binding protein She2p GCR1_C PF12550.8 CAR29915.1 - 1e-24 86.7 0.3 2.4e-24 85.4 0.3 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes ETX_MTX2 PF03318.13 CAR29915.1 - 0.05 13.4 0.1 0.072 12.9 0.1 1.2 1 0 0 1 1 1 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Med11 PF10280.9 CAR29916.1 - 7.1e-14 52.4 2.1 1.8e-13 51.1 2.1 1.6 1 1 0 1 1 1 1 Mediator complex protein Syntaxin-6_N PF09177.11 CAR29916.1 - 0.0067 17.0 0.6 0.0087 16.6 0.6 1.2 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Tsc35 PF15079.6 CAR29916.1 - 0.03 13.9 1.3 0.043 13.4 1.1 1.4 1 1 0 1 1 1 0 Testis-specific protein 35 CM_2 PF01817.21 CAR29916.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Chorismate mutase type II Mur_ligase_M PF08245.12 CAR29917.1 - 3e-07 30.6 0.0 1.5e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CAR29917.1 - 0.031 14.5 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain SRAP PF02586.14 CAR29918.1 - 5.4e-71 238.6 1.9 7.2e-71 238.2 1.9 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) TPR_10 PF13374.6 CAR29919.1 - 0.00043 20.1 1.4 0.85 9.6 0.1 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR29919.1 - 0.0011 19.2 2.2 3.2 8.1 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat NodA PF02474.15 CAR29919.1 - 0.11 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein A (NodA) Peptidase_M3 PF01432.20 CAR29920.1 - 2e-134 449.3 0.0 2.7e-134 448.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 WD40 PF00400.32 CAR29921.1 - 4.2e-44 147.6 9.8 2.3e-07 31.4 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29921.1 - 3.9e-08 33.5 0.6 0.052 13.9 0.0 4.4 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR29921.1 - 7.8e-07 28.1 5.2 0.0076 14.9 0.2 4.7 2 1 3 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CAR29921.1 - 1.4e-05 25.1 0.5 0.0017 18.2 0.1 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CAR29921.1 - 4.1e-05 22.7 0.2 0.54 9.1 0.0 3.6 2 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Adaptin_N PF01602.20 CAR29922.1 - 5.2e-120 401.5 18.0 6.6e-120 401.1 18.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CAR29922.1 - 1e-51 175.2 5.9 1e-51 175.2 5.9 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CAR29922.1 - 1.2e-08 35.2 1.2 8e-05 23.0 0.1 5.0 4 1 2 6 6 6 2 HEAT repeats HEAT PF02985.22 CAR29922.1 - 4e-07 29.7 1.1 0.05 13.9 0.0 5.1 4 0 0 4 4 4 1 HEAT repeat Atx10homo_assoc PF09759.9 CAR29922.1 - 0.017 15.2 1.0 0.52 10.4 0.0 3.3 2 1 1 3 3 3 0 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 CAR29922.1 - 0.025 15.1 0.2 2 9.0 0.0 3.7 4 0 0 4 4 4 0 HEAT-like repeat Arm PF00514.23 CAR29922.1 - 0.03 14.4 4.4 0.086 12.9 0.4 3.8 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat Cmc1 PF08583.10 CAR29923.1 - 4.3e-18 65.1 4.7 6.1e-18 64.6 4.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CAR29923.1 - 0.012 15.7 1.6 0.029 14.5 1.4 1.7 1 1 0 1 1 1 0 CHCH domain CX9C PF16860.5 CAR29923.1 - 0.051 13.6 3.4 3.2 7.8 0.4 2.2 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 CAR29923.1 - 0.22 11.9 4.6 5.7 7.4 0.4 2.4 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) L31 PF09784.9 CAR29924.1 - 1.7e-42 144.0 2.2 2.9e-42 143.3 2.2 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L31 Spc24 PF08286.11 CAR29925.1 - 2.9e-23 82.1 12.3 3e-23 82.0 1.1 2.3 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 HIP1_clath_bdg PF16515.5 CAR29925.1 - 4.3e-05 24.0 8.5 4.3e-05 24.0 8.5 2.1 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 HMMR_N PF15905.5 CAR29925.1 - 0.0026 17.3 10.9 0.0033 16.9 10.9 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 CAR29925.1 - 0.012 15.1 11.8 0.015 14.8 11.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2968 PF11180.8 CAR29925.1 - 0.014 15.1 7.5 0.019 14.6 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Allexi_40kDa PF05549.11 CAR29925.1 - 0.017 14.6 3.6 0.023 14.2 3.6 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein NPV_P10 PF05531.12 CAR29925.1 - 0.028 14.9 2.4 0.028 14.9 2.4 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 CAR29925.1 - 0.031 14.3 9.0 0.049 13.7 9.0 1.3 1 0 0 1 1 1 0 Laminin Domain II PKcGMP_CC PF16808.5 CAR29925.1 - 0.035 13.9 1.3 0.16 11.8 0.0 2.6 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 CAR29925.1 - 0.039 13.3 5.0 0.054 12.8 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 CAR29925.1 - 0.044 14.2 8.2 0.066 13.6 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 CAR29925.1 - 0.052 13.6 4.9 0.46 10.5 1.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 CAR29925.1 - 0.072 12.7 4.7 0.081 12.5 4.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GrpE PF01025.19 CAR29925.1 - 0.075 12.7 7.1 0.12 12.1 7.1 1.2 1 0 0 1 1 1 0 GrpE BLOC1_2 PF10046.9 CAR29925.1 - 0.076 13.3 8.2 0.16 12.3 7.6 1.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PhaP_Bmeg PF09602.10 CAR29925.1 - 0.1 12.5 10.3 0.25 11.3 7.6 2.3 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Spc7 PF08317.11 CAR29925.1 - 0.11 11.4 11.4 0.16 10.8 11.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CAR29925.1 - 0.11 10.4 8.5 0.15 10.0 8.5 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 CAR29925.1 - 0.11 13.0 9.8 0.18 12.3 9.8 1.4 1 0 0 1 1 1 0 AAA domain TMF_DNA_bd PF12329.8 CAR29925.1 - 0.14 12.2 13.3 0.94 9.5 11.3 2.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.14 CAR29925.1 - 0.25 11.7 14.7 0.95 9.8 14.7 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.13 CAR29925.1 - 0.4 9.9 5.9 0.5 9.6 5.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein AAA_13 PF13166.6 CAR29925.1 - 0.44 9.1 9.7 0.46 9.1 4.1 1.9 1 1 1 2 2 2 0 AAA domain DUF641 PF04859.12 CAR29925.1 - 0.72 10.2 7.7 0.21 11.9 3.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 CAR29925.1 - 1.7 8.7 9.2 3.2 7.8 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CAR29925.1 - 2.1 8.8 8.6 2 8.9 2.2 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) BST2 PF16716.5 CAR29925.1 - 2.8 8.6 10.3 9.9 6.8 9.8 2.1 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 ACCA PF03255.14 CAR29925.1 - 3.4 7.6 6.7 3.3 7.6 2.8 2.1 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit YabA PF06156.13 CAR29925.1 - 7.5 7.3 7.3 8.4 7.1 2.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA ABC_tran_CTD PF16326.5 CAR29925.1 - 7.9 6.8 11.5 14 6.0 4.7 2.9 1 1 2 3 3 3 0 ABC transporter C-terminal domain DASH_Hsk3 PF08227.11 CAR29926.1 - 4.8e-20 71.6 5.3 6.2e-20 71.3 5.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Pkinase PF00069.25 CAR29927.1 - 6.1e-75 252.0 0.0 9.9e-75 251.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29927.1 - 3.8e-35 121.4 0.0 6e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CAR29927.1 - 5.6e-08 32.1 0.3 1.7e-07 30.5 0.2 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CAR29927.1 - 6.6e-08 32.2 0.0 1.6e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CAR29927.1 - 0.0091 15.4 0.3 0.053 12.9 0.3 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CAR29927.1 - 0.017 14.2 0.2 0.028 13.5 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 CAR29927.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CAR29927.1 - 0.043 12.6 0.0 0.043 12.6 0.0 2.1 3 0 0 3 3 3 0 Fungal protein kinase Abhydrolase_1 PF00561.20 CAR29928.1 - 7.9e-34 117.4 0.1 1.1e-33 117.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CAR29928.1 - 6.8e-22 76.8 0.1 1.4e-21 75.8 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CAR29928.1 - 8.5e-07 28.5 0.0 0.0042 16.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 CAR29928.1 - 0.00019 21.2 0.0 0.6 9.7 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CAR29928.1 - 0.0043 16.9 0.0 1.6 8.5 0.0 2.4 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Sdh_cyt PF01127.22 CAR29929.1 - 1.1e-24 86.8 2.4 1.4e-24 86.5 2.4 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SH3_1 PF00018.28 CAR29930.1 - 2.5e-14 52.6 0.1 3.8e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CAR29930.1 - 5.7e-11 42.1 0.0 9.7e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CAR29930.1 - 8.1e-10 38.2 0.1 1.2e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 CAR29930.1 - 0.04 14.0 6.6 0.056 13.5 6.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Rubella_Capsid PF05750.11 CAR29930.1 - 0.043 13.4 3.8 0.047 13.3 3.8 1.1 1 0 0 1 1 1 0 Rubella capsid protein CCDC53 PF10152.9 CAR29930.1 - 0.094 13.1 2.1 0.099 13.1 2.1 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex hSH3 PF14603.6 CAR29930.1 - 0.12 12.9 0.1 0.23 11.9 0.1 1.4 1 1 0 1 1 1 0 Helically-extended SH3 domain DUF3484 PF11983.8 CAR29930.1 - 1.2 10.3 8.5 0.29 12.3 5.0 1.8 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch FlaC_arch PF05377.11 CAR29931.1 - 0.013 15.9 1.9 0.027 14.9 1.9 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 CAR29931.1 - 0.053 14.2 2.6 0.053 14.2 2.6 1.6 2 0 0 2 2 2 0 Occludin homology domain DivIC PF04977.15 CAR29931.1 - 0.07 12.9 4.6 0.2 11.5 4.5 1.8 1 1 0 1 1 1 0 Septum formation initiator DUF4407 PF14362.6 CAR29931.1 - 0.24 10.7 5.1 0.35 10.2 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5428 PF17493.2 CAR29931.1 - 1.1 9.8 0.0 1.1 9.8 0.0 2.6 3 1 0 3 3 3 0 Family of unknown function (DUF5428) Snf7 PF03357.21 CAR29932.1 - 2.9e-53 180.0 17.9 2.9e-53 180.0 17.9 1.8 2 0 0 2 2 2 1 Snf7 Snapin_Pallidin PF14712.6 CAR29932.1 - 0.87 10.1 17.6 0.13 12.7 7.1 3.4 2 1 2 4 4 4 0 Snapin/Pallidin Cob_adeno_trans PF01923.18 CAR29932.1 - 3.4 7.8 6.2 1.8 8.6 1.6 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase FapA PF03961.13 CAR29932.1 - 5.5 5.5 15.7 0.57 8.7 10.7 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A SNARE PF05739.19 CAR29933.1 - 8.2e-15 54.5 1.4 1.9e-14 53.4 1.4 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CAR29933.1 - 0.00014 21.7 1.5 0.00014 21.7 1.5 2.8 2 1 1 3 3 3 1 Syntaxin Syntaxin-18_N PF10496.9 CAR29933.1 - 0.029 14.6 3.8 0.029 14.6 3.8 2.1 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus DUF16 PF01519.16 CAR29933.1 - 0.063 13.8 1.0 0.063 13.8 1.0 2.9 3 0 0 3 3 3 0 Protein of unknown function DUF16 Serine_rich PF08824.10 CAR29933.1 - 0.069 13.1 2.5 8.4 6.4 0.1 2.6 2 1 1 3 3 3 0 Serine rich protein interaction domain DUF5126 PF17166.4 CAR29933.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) MCPsignal PF00015.21 CAR29933.1 - 0.16 11.8 3.5 0.11 12.3 0.9 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 CAR29933.1 - 0.2 12.0 3.0 1 9.7 0.3 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MutS_III PF05192.18 CAR29933.1 - 0.46 10.7 3.1 0.82 9.9 3.1 1.5 1 1 0 1 1 1 0 MutS domain III Tim54 PF11711.8 CAR29934.1 - 3.3e-130 434.2 2.8 3.9e-130 434.0 2.8 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Lysine_decarbox PF03641.14 CAR29935.1 - 7.3e-42 142.6 0.1 9.3e-42 142.2 0.1 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CAR29935.1 - 4.5e-10 39.3 0.1 5.9e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 CAR29935.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote DAGK_cat PF00781.24 CAR29935.1 - 0.12 12.0 0.1 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Aldo_ket_red PF00248.21 CAR29936.1 - 3.8e-24 85.4 0.0 4.9e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.6 CAR29937.1 - 3.8e-22 77.6 46.2 4.4e-08 33.2 2.0 7.4 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 CAR29937.1 - 5.2e-13 48.6 31.4 6.9e-07 29.1 1.0 6.7 4 1 1 5 5 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CAR29937.1 - 1.4e-12 47.4 19.6 2.5e-06 27.6 2.6 10.8 11 0 0 11 11 9 5 Zinc finger, C2H2 type Zap1_zf2 PF18217.1 CAR29937.1 - 2.2e-12 46.7 11.4 2.2e-12 46.7 11.4 5.3 4 0 0 4 4 3 1 Zap1 zinc finger 2 zf-C2H2_4 PF13894.6 CAR29937.1 - 8.3e-09 35.6 18.5 0.00015 22.3 1.4 12.1 12 0 0 12 12 10 6 C2H2-type zinc finger zf-met PF12874.7 CAR29937.1 - 0.00027 21.2 1.3 0.00027 21.2 1.3 6.8 7 0 0 7 7 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CAR29937.1 - 0.0022 18.2 0.5 0.0022 18.2 0.5 7.0 7 0 0 7 7 5 3 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CAR29937.1 - 0.0065 17.1 1.2 0.0065 17.1 1.2 8.2 7 2 2 9 9 7 4 FOXP coiled-coil domain zf-C2HC_2 PF13913.6 CAR29937.1 - 0.024 14.5 18.5 0.14 12.1 0.2 5.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 CAR29937.1 - 0.038 13.7 27.0 0.46 10.3 1.2 6.2 6 0 0 6 6 6 0 zinc-finger C2H2-type Sigma70_ner PF04546.13 CAR29937.1 - 0.07 13.0 7.1 0.13 12.1 7.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 CAR29937.1 - 0.28 9.4 9.0 0.46 8.7 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CAR29937.1 - 0.48 9.8 12.6 0.95 8.8 12.6 1.4 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 CAR29937.1 - 3.2 5.7 19.0 4.8 5.1 19.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 CAR29937.1 - 6.4 4.8 19.5 0.15 10.2 12.7 1.6 2 0 0 2 2 2 0 Nop14-like family FAM176 PF14851.6 CAR29937.1 - 7.5 6.2 12.8 24 4.6 12.8 1.9 1 0 0 1 1 1 0 FAM176 family Merozoite_SPAM PF07133.11 CAR29937.1 - 8.3 6.4 25.8 17 5.3 25.8 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Methyltransf_16 PF10294.9 CAR29938.1 - 1.4e-19 70.5 0.0 2.5e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CAR29938.1 - 7.1e-07 29.2 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR29938.1 - 0.0013 18.5 0.0 0.0036 17.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CAR29938.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF1397 PF07165.11 CAR29938.1 - 0.024 14.0 0.4 0.039 13.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) Methyltransf_12 PF08242.12 CAR29938.1 - 0.035 14.8 0.0 0.073 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CAR29938.1 - 0.071 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Rpr2 PF04032.16 CAR29938.1 - 0.081 13.2 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pkinase PF00069.25 CAR29939.1 - 4.4e-34 118.0 0.0 2.2e-33 115.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR29939.1 - 7.1e-21 74.7 0.0 4.7e-20 72.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR29939.1 - 0.00043 19.2 0.0 0.00065 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CAR29939.1 - 0.0018 17.7 0.2 0.01 15.2 0.1 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CAR29939.1 - 0.0065 16.1 0.1 0.075 12.6 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CAR29939.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf_UBZ PF18439.1 CAR29939.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger HbrB PF08539.11 CAR29940.1 - 5.3e-38 130.7 5.7 3.3e-37 128.1 5.7 2.2 1 1 0 1 1 1 1 HbrB-like CLN3 PF02487.17 CAR29941.1 - 1.5e-150 501.7 8.2 1.8e-150 501.5 8.2 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 CAR29941.1 - 5.5e-08 32.1 15.4 3e-05 23.1 3.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PrgI PF12666.7 CAR29941.1 - 0.49 11.1 0.0 0.49 11.1 0.0 3.5 3 2 1 4 4 4 0 PrgI family protein Aminotran_1_2 PF00155.21 CAR29942.1 - 3.6e-81 273.1 0.0 4.3e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CAR29942.1 - 0.013 14.8 0.0 0.026 13.9 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CAR29942.1 - 0.024 13.2 0.1 0.053 12.0 0.1 1.6 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF2240 PF09999.9 CAR29942.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) DUF1674 PF07896.12 CAR29943.1 - 6.4e-18 65.0 2.4 1.3e-17 64.0 2.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Ribosomal_L37 PF08561.10 CAR29945.1 - 3.5e-23 82.4 8.5 8.5e-18 65.0 0.3 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 Phosphodiest PF01663.22 CAR29946.1 - 2.3e-12 47.2 0.7 1e-08 35.2 0.1 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CAR29946.1 - 0.00036 20.0 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CAR29946.1 - 0.0059 16.0 0.1 0.014 14.8 0.1 1.7 2 0 0 2 2 2 1 Sulfatase MCU PF04678.13 CAR29946.1 - 0.49 10.5 0.0 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF2207 PF09972.9 CAR29946.1 - 1.2 7.9 5.6 0.94 8.2 0.8 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MMPL PF03176.15 CAR29946.1 - 1.9 7.3 4.6 3.2 6.6 4.6 1.2 1 0 0 1 1 1 0 MMPL family zf-C2H2_2 PF12756.7 CAR29947.1 - 2.9e-38 130.3 2.0 1.1e-34 118.7 0.6 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CAR29947.1 - 0.028 15.2 5.3 2.1 9.4 0.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger PP_kinase_C PF13090.6 CAR29947.1 - 0.052 13.0 0.2 0.052 13.0 0.2 1.7 2 0 0 2 2 2 0 Polyphosphate kinase C-terminal domain 2 zf-C2H2_6 PF13912.6 CAR29947.1 - 0.26 11.3 2.3 0.23 11.5 0.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CAR29947.1 - 0.41 11.2 0.1 0.41 11.2 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CAR29947.1 - 1.6 9.1 7.3 1.4 9.3 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding NOA36 PF06524.12 CAR29947.1 - 4 6.7 13.2 0.091 12.1 2.0 2.4 2 0 0 2 2 2 0 NOA36 protein zf-met PF12874.7 CAR29947.1 - 8.8 6.9 9.1 6.1 7.4 0.2 3.4 4 0 0 4 4 4 0 Zinc-finger of C2H2 type adh_short PF00106.25 CAR29948.1 - 1.8e-16 60.2 0.0 1.4e-15 57.3 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR29948.1 - 1.1e-12 48.3 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CAR29948.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Mrpl_C PF18502.1 CAR29950.1 - 7.9e-41 138.8 1.0 2e-40 137.6 0.9 1.7 2 0 0 2 2 2 1 54S ribosomal protein L8 C-terminal domain Ribosomal_L17 PF01196.19 CAR29950.1 - 7.2e-27 94.1 0.0 5.4e-26 91.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L17 PALP PF00291.25 CAR29951.1 - 6.2e-62 209.7 0.0 7.1e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DSPc PF00782.20 CAR29952.1 - 1.5e-25 89.5 0.0 3.7e-21 75.3 0.1 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CAR29952.1 - 0.00021 20.9 0.1 0.00052 19.7 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CAR29952.1 - 0.023 14.4 0.1 0.07 12.8 0.1 1.8 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 CAR29952.1 - 0.044 14.1 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Rit1 DUSP-like domain CBFD_NFYB_HMF PF00808.23 CAR29953.1 - 0.0023 18.2 0.0 0.0056 16.9 0.0 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ndufs5 PF10200.9 CAR29953.1 - 0.02 15.1 0.0 0.045 14.0 0.0 1.6 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF2310 PF10071.9 CAR29953.1 - 0.072 12.4 1.3 0.073 12.3 0.1 1.5 2 0 0 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Cwf_Cwc_15 PF04889.12 CAR29953.1 - 1.1 9.0 25.6 0.011 15.5 15.6 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein MPM1 PF17234.2 CAR29954.1 - 6.2e-55 186.1 0.7 7.9e-55 185.7 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 HicB_lk_antitox PF15919.5 CAR29954.1 - 0.2 11.8 0.0 0.34 11.0 0.0 1.3 1 0 0 1 1 1 0 HicB_like antitoxin of bacterial toxin-antitoxin system Paf1 PF03985.13 CAR29955.1 - 2.4e-107 359.6 22.0 2.4e-107 359.6 22.0 2.0 1 1 1 2 2 2 1 Paf1 Esterase PF00756.20 CAR29956.1 - 2.2e-61 207.7 0.2 2.6e-61 207.5 0.2 1.0 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 CAR29956.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Phage_holin_T PF11031.8 CAR29956.1 - 0.029 13.9 0.0 0.7 9.3 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage T holin Esterase_phd PF10503.9 CAR29956.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Esterase PHB depolymerase RCC1_2 PF13540.6 CAR29957.1 - 5.9e-19 67.4 4.5 1.4e-08 34.3 1.0 4.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CAR29957.1 - 1.8e-14 54.1 0.4 0.0022 18.6 0.5 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Peptidase_M20 PF01546.28 CAR29958.1 - 2.6e-22 79.5 0.0 3.7e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR29958.1 - 1.9e-11 43.8 0.0 3.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 CAR29958.1 - 3e-09 37.4 8.7 0.007 17.2 0.1 6.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29958.1 - 0.00024 21.3 0.0 0.44 10.9 0.0 3.0 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR29958.1 - 0.0075 15.0 0.4 0.83 8.2 0.0 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40 PF00400.32 CAR29959.1 - 9.9e-14 51.5 0.1 0.0016 19.2 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29959.1 - 5e-08 33.1 0.0 0.035 14.4 0.0 4.6 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain MRP-L27 PF09809.9 CAR29961.1 - 1.1e-33 115.4 1.4 1.5e-33 115.0 1.4 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SecY PF00344.20 CAR29962.1 - 1.4e-39 136.2 14.3 1.9e-39 135.8 14.3 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CAR29962.1 - 1.5e-10 40.7 0.9 1.5e-09 37.6 0.0 2.6 2 0 0 2 2 2 1 Plug domain of Sec61p A_deaminase PF00962.22 CAR29963.1 - 3.2e-25 89.2 0.0 3.2e-11 43.1 0.0 3.9 2 1 0 2 2 2 2 Adenosine/AMP deaminase NAT PF04768.13 CAR29964.1 - 5.6e-49 166.1 0.0 1.9e-48 164.4 0.1 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase baeRF_family11 PF18855.1 CAR29964.1 - 0.015 15.6 0.0 0.08 13.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 11 CobN-Mg_chel PF02514.16 CAR29964.1 - 0.11 10.2 0.0 0.14 9.8 0.0 1.2 1 0 0 1 1 1 0 CobN/Magnesium Chelatase Sld5 PF05916.11 CAR29965.1 - 4.8e-17 62.4 2.0 7.7e-17 61.7 2.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF790 PF05626.11 CAR29965.1 - 0.012 14.4 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Peptidase_M28 PF04389.17 CAR29967.1 - 6.7e-39 133.6 0.1 1e-38 133.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CAR29967.1 - 6.4e-09 35.7 0.0 1.8e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CAR29967.1 - 4.3e-05 23.3 0.0 8.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DnaJ PF00226.31 CAR29968.1 - 2e-20 72.7 4.4 4.3e-20 71.6 4.4 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4460 PF14687.6 CAR29968.1 - 0.001 19.1 0.4 0.001 19.1 0.4 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4460) GRP PF07172.11 CAR29968.1 - 0.43 11.3 13.1 1.2 9.9 13.1 1.7 1 0 0 1 1 1 0 Glycine rich protein family Mem_trans PF03547.18 CAR29969.1 - 4.2e-66 222.9 8.0 2.8e-65 220.2 8.0 1.8 1 1 0 1 1 1 1 Membrane transport protein SMC_N PF02463.19 CAR29970.1 - 2.1e-51 174.5 61.5 8.5e-51 172.5 61.5 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CAR29970.1 - 3.9e-29 101.3 0.0 2e-28 99.1 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CAR29970.1 - 4.7e-17 63.1 0.8 4.7e-17 63.1 0.8 7.6 2 2 3 5 5 3 1 AAA domain AAA_21 PF13304.6 CAR29970.1 - 4.3e-12 46.5 18.0 2.5e-08 34.1 0.7 4.1 4 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CAR29970.1 - 3.5e-06 27.0 89.8 5.4e-06 26.3 30.0 4.6 2 2 1 3 3 3 2 AAA ATPase domain DUF4795 PF16043.5 CAR29970.1 - 0.00022 20.9 16.4 0.00022 20.9 16.4 6.6 2 2 3 5 5 3 1 Domain of unknown function (DUF4795) BRCT PF00533.26 CAR29970.1 - 0.0021 18.4 0.2 3.7 8.0 0.0 4.8 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain BLOC1_2 PF10046.9 CAR29970.1 - 0.0037 17.5 0.8 0.0037 17.5 0.8 10.5 6 3 5 11 11 11 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_29 PF13555.6 CAR29970.1 - 0.008 15.9 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ERM PF00769.19 CAR29970.1 - 0.017 14.9 0.7 0.017 14.9 0.7 7.0 2 1 2 6 6 6 0 Ezrin/radixin/moesin family ABC_tran PF00005.27 CAR29970.1 - 0.057 13.9 0.1 0.057 13.9 0.1 6.4 3 2 0 4 4 3 0 ABC transporter CbiA PF01656.23 CAR29970.1 - 6.6 6.8 6.1 1.5e+02 2.4 6.1 3.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Cytokin_check_N PF10407.9 CAR29971.1 - 6.2e-32 109.4 0.8 1.4e-31 108.2 0.8 1.7 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.26 CAR29972.1 - 2.1e-17 64.2 0.7 2.1e-17 64.2 0.7 2.1 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Hamartin PF04388.12 CAR29972.1 - 4 6.0 25.1 5.3 5.6 25.1 1.1 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 CAR29972.1 - 6 6.8 14.6 7.4 6.4 14.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KH_1 PF00013.29 CAR29973.1 - 3.3e-86 283.1 21.6 1.1e-12 47.5 0.4 12.4 12 0 0 12 12 12 9 KH domain KH_2 PF07650.17 CAR29973.1 - 3e-10 39.8 17.2 0.0015 18.4 0.0 6.7 5 2 1 6 6 6 3 KH domain KH_5 PF13184.6 CAR29973.1 - 1.2e-06 28.5 16.4 0.22 11.7 0.2 6.6 7 0 0 7 7 7 3 NusA-like KH domain KH_4 PF13083.6 CAR29973.1 - 0.011 15.6 12.0 0.15 12.0 0.0 6.6 6 1 1 7 7 7 0 KH domain ANAPC9 PF12856.7 CAR29973.1 - 0.014 15.6 1.0 0.058 13.6 1.0 2.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 UPF0184 PF03670.13 CAR29973.1 - 0.16 12.4 1.0 0.82 10.1 0.2 2.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) BMC PF00936.19 CAR29973.1 - 0.33 11.0 1.3 1.3e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 BMC domain SLS PF14611.6 CAR29973.1 - 0.73 9.6 21.0 21 4.9 1.1 7.1 3 1 3 7 7 7 0 Mitochondrial inner-membrane-bound regulator Ras PF00071.22 CAR29974.1 - 2.2e-53 180.2 0.4 2.6e-53 179.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR29974.1 - 1e-36 125.8 0.2 1.5e-36 125.3 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR29974.1 - 1.2e-13 50.9 0.0 1.7e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR29974.1 - 2.1e-06 27.2 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR29974.1 - 1.3e-05 25.3 0.1 2.4e-05 24.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR29974.1 - 0.00032 20.3 0.1 0.00054 19.6 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CAR29974.1 - 0.00032 20.6 0.2 0.96 9.3 0.1 2.5 1 1 2 3 3 3 2 RsgA GTPase ABC1 PF03109.16 CAR29974.1 - 0.019 15.1 0.0 0.086 13.0 0.0 2.0 3 0 0 3 3 3 0 ABC1 family TniB PF05621.11 CAR29974.1 - 0.026 13.9 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 CAR29974.1 - 0.038 13.3 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.22 CAR29974.1 - 0.041 14.3 0.0 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 CAR29974.1 - 0.083 13.3 0.1 0.13 12.6 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain Mitofilin PF09731.9 CAR29975.1 - 4.2e-42 144.8 12.0 3e-35 122.2 11.6 2.0 1 1 0 2 2 2 2 Mitochondrial inner membrane protein MULE PF10551.9 CAR29975.1 - 0.076 13.4 0.0 0.27 11.7 0.0 1.9 1 0 0 1 1 1 0 MULE transposase domain DUF2443 PF10398.9 CAR29975.1 - 0.086 12.9 1.0 11 6.1 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2443) FAM76 PF16046.5 CAR29975.1 - 0.28 10.5 5.5 0.46 9.8 5.5 1.3 1 0 0 1 1 1 0 FAM76 protein DUF1818 PF08848.11 CAR29975.1 - 0.83 9.8 3.5 28 4.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1818) Actin PF00022.19 CAR29976.1 - 1.8e-96 323.3 0.0 9.1e-95 317.6 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CAR29976.1 - 0.034 13.0 0.0 0.18 10.6 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein IBR PF01485.21 CAR29977.1 - 3.7e-17 62.3 42.2 1.1e-09 38.4 4.8 3.8 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CAR29977.1 - 1.2e-06 28.2 13.3 1.2e-06 28.2 13.3 4.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CAR29977.1 - 0.0016 18.6 11.8 0.0016 18.6 11.8 4.4 3 1 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CAR29977.1 - 0.0025 17.6 5.8 0.0025 17.6 5.8 5.2 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF3808 PF10300.9 CAR29978.1 - 3.2e-166 553.8 0.8 3.7e-166 553.6 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_9 PF13371.6 CAR29978.1 - 0.01 16.0 0.3 0.79 9.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_4 PF12763.7 CAR29979.1 - 0.0088 16.0 0.3 0.022 14.7 0.3 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Vps51 PF08700.11 CAR29980.1 - 1.7e-12 47.2 4.4 1.7e-12 47.2 4.4 1.7 2 0 0 2 2 2 1 Vps51/Vps67 HBS1_N PF08938.10 CAR29980.1 - 0.0083 16.4 4.7 0.014 15.7 4.7 1.5 1 1 0 1 1 1 1 HBS1 N-terminus Stn1 PF10451.9 CAR29980.1 - 0.02 13.9 3.0 0.025 13.6 3.0 1.1 1 0 0 1 1 1 0 Telomere regulation protein Stn1 DUF4050 PF13259.6 CAR29980.1 - 0.15 12.4 4.3 0.19 12.0 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF1682 PF07946.14 CAR29980.1 - 0.34 10.1 8.1 0.56 9.4 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Med21 PF11221.8 CAR29980.1 - 1.1 9.5 9.4 0.33 11.2 2.8 2.3 1 1 1 2 2 2 0 Subunit 21 of Mediator complex DAO PF01266.24 CAR29981.1 - 4.1e-26 92.4 0.0 5.8e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase SH3_6 PF12913.7 CAR29981.1 - 0.0076 15.8 0.2 0.024 14.2 0.2 1.8 1 0 0 1 1 1 1 SH3 domain (SH3b1 type) Symplekin_C PF12295.8 CAR29981.1 - 0.057 13.5 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal Pyr_redox PF00070.27 CAR29981.1 - 0.083 13.5 0.2 0.23 12.0 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CAR29981.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.18 CAR29981.1 - 0.22 11.8 0.1 0.4 10.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain EF-hand_7 PF13499.6 CAR29982.1 - 6.8e-10 39.3 0.9 6.3e-08 33.0 0.6 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CAR29982.1 - 7.8e-09 34.8 2.0 0.00013 21.6 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 CAR29982.1 - 7.8e-08 32.0 0.5 2.8e-06 27.1 0.3 2.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 CAR29982.1 - 1.7e-07 30.2 5.0 0.00036 19.9 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 CAR29982.1 - 5.2e-07 29.9 0.0 0.0071 16.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 CAR29982.1 - 0.012 15.9 0.0 0.67 10.3 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain RNA_binding PF01877.17 CAR29982.1 - 0.047 14.0 0.5 3.1 8.1 0.1 2.2 1 1 1 2 2 2 0 RNA binding UPF0154 PF03672.13 CAR29982.1 - 0.054 13.5 0.0 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 CAR29982.1 - 0.078 12.9 0.1 0.19 11.7 0.1 1.6 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand FDX-ACB PF03147.14 CAR29982.1 - 0.11 12.9 0.1 0.23 11.9 0.1 1.6 1 1 0 1 1 1 0 Ferredoxin-fold anticodon binding domain EF-hand_11 PF08976.11 CAR29982.1 - 0.17 12.8 0.0 0.26 12.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain PAS PF00989.25 CAR29983.1 - 1.8e-17 63.3 0.0 8.9e-17 61.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 CAR29983.1 - 3.4e-06 27.1 8.4 6.1e-06 26.3 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.10 CAR29983.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold tRNA_bind PF01588.20 CAR29984.1 - 4.3e-29 100.5 0.3 7.3e-29 99.7 0.3 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Presenilin PF01080.17 CAR29984.1 - 0.37 9.5 2.3 0.51 9.1 2.3 1.2 1 0 0 1 1 1 0 Presenilin TP53IP5 PF15331.6 CAR29984.1 - 0.74 9.9 9.4 1.9 8.6 9.4 1.6 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Zn_clus PF00172.18 CAR29985.1 - 3.4e-09 36.7 12.9 9.3e-09 35.3 12.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 CAR29986.1 - 8.6e-102 341.3 17.8 1.1e-101 341.0 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR29986.1 - 8.3e-28 97.3 37.4 4.6e-22 78.4 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CAR29986.1 - 1.1e-08 34.1 31.9 3.4e-06 25.9 2.5 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 CAR29986.1 - 8e-07 27.9 3.6 8e-07 27.9 3.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Ribosomal_L27A PF00828.19 CAR29987.1 - 3.1e-21 76.4 0.1 4.1e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HD_3 PF13023.6 CAR29988.1 - 3.5e-38 131.1 2.6 4.1e-38 130.9 2.6 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CAR29988.1 - 1.5e-11 44.4 1.7 2.1e-11 43.9 1.7 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CAR29988.1 - 3.4e-05 24.1 0.4 5.6e-05 23.4 0.4 1.4 1 0 0 1 1 1 1 HD domain Glycos_transf_4 PF00953.21 CAR29989.1 - 5.1e-31 107.8 10.5 5.1e-31 107.8 10.5 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 4 WD40 PF00400.32 CAR29990.1 - 5e-23 81.0 13.3 5.7e-05 23.8 0.6 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR29990.1 - 2e-13 50.4 0.3 0.005 17.1 0.0 3.8 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain YmzC PF14157.6 CAR29990.1 - 0.03 14.4 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 0 YmzC-like protein SsgA PF04686.12 CAR29990.1 - 0.04 13.9 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA GSHPx PF00255.19 CAR29991.1 - 2.8e-46 155.5 0.2 3.9e-46 155.1 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CAR29991.1 - 2.6e-05 24.1 0.1 9.8e-05 22.3 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CAR29991.1 - 0.00027 20.7 0.0 0.0012 18.6 0.0 1.9 1 1 0 1 1 1 1 Redoxin SNF2_N PF00176.23 CAR29992.1 - 7.4e-74 248.5 0.3 1.7e-73 247.4 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CAR29992.1 - 5.6e-39 132.7 1.3 5.6e-39 132.7 1.3 3.7 4 0 0 4 4 3 1 SLIDE HAND PF09110.11 CAR29992.1 - 8.1e-30 103.8 3.5 8.1e-30 103.8 3.5 4.4 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 CAR29992.1 - 1.5e-19 70.4 0.6 9.6e-19 67.8 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR29992.1 - 2.2e-09 37.5 0.0 2.2e-09 37.5 0.0 3.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CAR29992.1 - 0.00043 20.1 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CAR29992.1 - 0.00068 18.9 0.1 0.00068 18.9 0.1 2.1 2 1 0 2 2 1 1 ERCC3/RAD25/XPB C-terminal helicase Myb_DNA-binding PF00249.31 CAR29992.1 - 0.0016 18.6 0.0 0.45 10.8 0.0 3.7 2 1 0 2 2 2 1 Myb-like DNA-binding domain AAA_14 PF13173.6 CAR29992.1 - 0.043 13.9 0.4 0.18 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD_2 PF06733.15 CAR29992.1 - 0.079 12.6 0.1 0.079 12.6 0.1 1.9 2 0 0 2 2 2 0 DEAD_2 Ribosomal_L13e PF01294.18 CAR29992.1 - 0.079 12.8 0.1 0.079 12.8 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein L13e WD40 PF00400.32 CAR29993.1 - 0.023 15.6 5.1 1.9e+02 3.2 0.1 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat MMR_HSR1 PF01926.23 CAR29994.1 - 7.5e-16 58.2 0.1 2.8e-14 53.2 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR29994.1 - 1e-07 31.6 0.2 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAR29994.1 - 2.1e-07 31.0 0.7 0.0078 16.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CAR29994.1 - 0.011 15.1 0.1 0.022 14.1 0.1 1.5 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 CAR29994.1 - 0.41 10.7 8.1 0.15 12.1 1.3 3.2 3 1 0 3 3 3 0 Dynamin family Use1 PF09753.9 CAR29995.1 - 2.4e-10 40.6 0.0 3e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 MFS_1 PF07690.16 CAR29996.1 - 2.7e-31 108.8 32.5 2.7e-31 108.8 32.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR29996.1 - 1.2e-13 50.8 0.5 1.2e-13 50.8 0.5 3.3 3 2 1 5 5 5 1 Sugar (and other) transporter SecE PF00584.20 CAR29996.1 - 0.15 12.0 0.0 0.15 12.0 0.0 3.4 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex DAD PF02109.16 CAR29996.1 - 0.99 9.7 0.0 0.99 9.7 0.0 3.7 5 1 0 5 5 5 0 DAD family TssN PF17555.2 CAR29996.1 - 1.7 7.9 10.2 4.1 6.7 0.4 2.8 2 0 0 2 2 2 0 Type VI secretion system, TssN MFS_1 PF07690.16 CAR29997.1 - 2.6e-30 105.5 33.2 2.6e-30 105.5 33.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR29997.1 - 1.2e-09 37.5 5.4 1.2e-09 37.5 5.4 3.9 1 1 1 4 4 4 1 Sugar (and other) transporter DUF3937 PF13073.6 CAR29997.1 - 0.062 13.4 1.4 0.62 10.2 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3937) Bystin PF05291.11 CAR29998.1 - 6.7e-119 396.5 0.0 1.1e-118 395.8 0.0 1.3 1 0 0 1 1 1 1 Bystin SAC3_GANP PF03399.16 CAR29999.1 - 0.0095 15.3 0.5 0.013 14.9 0.5 1.1 1 0 0 1 1 1 1 SAC3/GANP family RCC1 PF00415.18 CAR30000.1 - 2.9e-64 213.5 2.8 7.8e-11 42.4 0.1 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CAR30000.1 - 3.3e-34 116.0 22.0 7.6e-08 32.0 0.0 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat His_biosynth PF00977.21 CAR30001.1 - 1.3e-45 155.6 0.2 5.4e-45 153.6 0.2 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 CAR30001.1 - 1.8e-20 73.5 0.0 3.3e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 CAR30001.1 - 5.6e-09 36.1 0.0 0.00018 21.4 0.0 2.2 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 CAR30001.1 - 3.8e-06 26.6 0.0 8.6e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 CAR30001.1 - 0.00071 19.4 0.2 0.39 10.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase C26 NMO PF03060.15 CAR30001.1 - 0.014 14.8 0.1 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Nitronate monooxygenase DAHP_synth_1 PF00793.20 CAR30002.1 - 1.9e-107 358.2 0.0 2.3e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Arrestin_C PF02752.22 CAR30003.1 - 6.5e-05 23.4 0.0 0.00032 21.1 0.0 2.2 2 2 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Homeobox_KN PF05920.11 CAR30004.1 - 1.8e-18 66.2 0.3 3.7e-18 65.1 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CAR30004.1 - 1.8e-05 24.5 0.3 5.4e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Homeodomain zf-CCHC PF00098.23 CAR30006.1 - 1.2e-06 28.3 1.5 1.2e-06 28.3 1.5 1.6 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 CAR30006.1 - 0.0073 16.6 0.4 0.014 15.7 0.4 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_5 PF14787.6 CAR30006.1 - 0.011 15.4 4.0 0.021 14.5 4.0 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 CAR30006.1 - 0.091 12.6 0.8 0.19 11.6 0.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Aconitase PF00330.20 CAR30007.1 - 4.6e-149 497.3 0.0 5.8e-149 497.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CAR30007.1 - 3.4e-47 160.0 0.0 6.1e-47 159.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain ABC_membrane PF00664.23 CAR30008.1 - 7.5e-60 202.9 39.1 4.6e-35 121.6 10.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CAR30008.1 - 5.3e-47 159.8 0.0 5e-28 98.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CAR30008.1 - 2.8e-10 40.0 8.4 0.047 13.1 4.7 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CAR30008.1 - 1.2e-06 28.6 6.6 0.024 14.4 0.0 4.9 5 1 1 6 6 6 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CAR30008.1 - 1.2e-06 28.5 0.2 0.029 14.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CAR30008.1 - 1.7e-05 24.5 0.3 0.02 14.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CAR30008.1 - 2.9e-05 24.4 1.2 0.031 14.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CAR30008.1 - 0.00051 20.5 0.2 1.9 8.8 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 CAR30008.1 - 0.00069 19.6 0.1 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_15 PF13175.6 CAR30008.1 - 0.0013 18.6 0.4 0.18 11.5 0.1 3.3 2 2 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 CAR30008.1 - 0.0077 16.0 0.6 0.65 9.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CAR30008.1 - 0.0081 15.5 0.2 2 7.6 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 CAR30008.1 - 0.0091 15.7 0.1 0.16 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CAR30008.1 - 0.011 15.8 6.0 2.5 8.1 0.2 4.1 4 0 0 4 4 4 0 Helicase HerA, central domain ABC_ATPase PF09818.9 CAR30008.1 - 0.015 14.1 1.8 1.5 7.5 0.1 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class NB-ARC PF00931.22 CAR30008.1 - 0.027 13.7 0.5 7.6 5.6 0.0 3.1 3 1 0 3 3 3 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 CAR30008.1 - 0.029 13.7 0.2 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 CAR30008.1 - 0.059 12.4 0.0 5.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 CAR30008.1 - 0.072 13.2 6.9 0.26 11.3 0.0 3.4 3 1 0 3 3 3 0 Dynamin family AAA_33 PF13671.6 CAR30008.1 - 0.073 13.2 0.2 1.5 9.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 CAR30008.1 - 0.079 12.7 1.4 16 5.2 0.0 3.3 4 0 0 4 4 3 0 IstB-like ATP binding protein DUF815 PF05673.13 CAR30008.1 - 0.11 11.7 0.2 13 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 CAR30008.1 - 0.14 12.7 0.0 27 5.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain DUF717 PF05338.12 CAR30008.1 - 0.16 12.1 0.1 0.47 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF717) DUF1772 PF08592.11 CAR30008.1 - 0.16 12.2 3.5 0.53 10.6 0.0 3.3 4 0 0 4 4 2 0 Domain of unknown function (DUF1772) NACHT PF05729.12 CAR30008.1 - 0.2 11.6 1.8 0.65 9.9 0.0 2.7 3 0 0 3 3 3 0 NACHT domain AAA_23 PF13476.6 CAR30008.1 - 0.81 10.1 11.4 14 6.1 8.0 3.3 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 CAR30008.1 - 1.3 8.6 6.0 0.34 10.5 0.1 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Cys_Met_Meta_PP PF01053.20 CAR30009.1 - 5e-146 486.1 0.0 5.7e-146 485.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CAR30009.1 - 8.4e-12 44.9 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CAR30009.1 - 7.9e-11 41.9 0.1 2.9e-10 40.0 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CAR30009.1 - 6.3e-09 35.3 0.2 9.2e-09 34.7 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 CAR30009.1 - 9.2e-05 21.1 0.1 0.00014 20.5 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 CAR30009.1 - 0.00045 19.6 0.0 0.0009 18.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 CAR30009.1 - 0.036 12.8 0.0 0.05 12.3 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS CPSase_L_D2 PF02786.17 CAR30009.1 - 0.093 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Asparaginase_C PF17763.1 CAR30009.1 - 0.098 12.9 0.0 0.24 11.6 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Gtr1_RagA PF04670.12 CAR30010.1 - 1.9e-65 220.4 0.7 2.5e-65 220.1 0.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CAR30010.1 - 0.00048 19.6 0.1 0.0017 17.8 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_14 PF13173.6 CAR30010.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 CAR30010.1 - 0.021 14.3 0.1 0.046 13.1 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit GTP_cyclohydro2 PF00925.20 CAR30010.1 - 0.029 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II TYW3 PF02676.14 CAR30011.1 - 1.4e-65 220.7 0.0 1.5e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase TYW3 MIF4G PF02854.19 CAR30012.1 - 2.9e-50 170.8 0.4 5.5e-50 169.9 0.4 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 CAR30012.1 - 3.9e-26 91.0 0.3 1.8e-25 88.9 0.3 2.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 AAA PF00004.29 CAR30013.1 - 5.6e-43 146.5 0.0 1e-42 145.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CAR30013.1 - 3e-14 52.5 0.6 8.9e-14 51.0 0.1 2.1 3 0 0 3 3 1 1 AAA+ lid domain AAA_2 PF07724.14 CAR30013.1 - 6.6e-07 29.6 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 CAR30013.1 - 6.9e-07 29.1 0.5 1.8e-06 27.8 0.5 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CAR30013.1 - 1.5e-06 28.2 0.0 5.4e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CAR30013.1 - 2.2e-05 24.9 0.0 0.00023 21.6 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CAR30013.1 - 5.8e-05 23.4 0.2 0.0084 16.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CAR30013.1 - 8.7e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CAR30013.1 - 0.0009 19.8 1.0 0.017 15.7 0.0 3.0 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CAR30013.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CAR30013.1 - 0.0019 18.4 0.0 0.0049 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CAR30013.1 - 0.0046 17.2 0.0 0.0091 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CAR30013.1 - 0.0062 16.4 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CAR30013.1 - 0.012 15.7 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 CAR30013.1 - 0.013 14.8 0.0 0.03 13.5 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain DUF2072 PF09845.9 CAR30013.1 - 0.016 15.5 1.0 0.032 14.5 1.0 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein PhoH PF02562.16 CAR30013.1 - 0.017 14.6 0.0 0.074 12.5 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 CAR30013.1 - 0.018 14.4 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CAR30013.1 - 0.019 15.0 0.0 0.04 13.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Tropomyosin PF00261.20 CAR30013.1 - 0.033 13.6 2.5 0.1 11.9 0.7 2.1 2 0 0 2 2 2 0 Tropomyosin Sigma54_activat PF00158.26 CAR30013.1 - 0.036 13.8 0.1 0.15 11.7 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CAR30013.1 - 0.042 14.3 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.13 CAR30013.1 - 0.045 12.9 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 CAR30013.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region CEP63 PF17045.5 CAR30013.1 - 0.058 13.3 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa AAA_24 PF13479.6 CAR30013.1 - 0.058 13.1 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CAR30013.1 - 0.059 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CAR30013.1 - 0.078 13.4 0.1 0.99 9.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CAR30013.1 - 0.086 12.1 0.0 0.27 10.5 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 CAR30013.1 - 0.094 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 CAR30013.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CAR30013.1 - 0.15 12.3 0.3 0.78 10.1 0.1 2.2 3 0 0 3 3 1 0 AAA domain NACHT PF05729.12 CAR30013.1 - 0.17 11.8 0.0 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Glyco_tran_28_C PF04101.16 CAR30014.1 - 5.1e-29 101.4 0.0 1.5e-28 99.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain HSP20 PF00011.21 CAR30015.1 - 1.4e-18 66.9 0.4 2.8e-18 65.9 0.1 1.6 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CAR30015.1 - 0.0015 18.0 0.1 0.0038 16.7 0.1 1.7 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Bac_luciferase PF00296.20 CAR30016.1 - 4.3e-45 154.5 0.0 6.3e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase FAD_binding_7 PF03441.14 CAR30017.1 - 1.6e-67 226.9 0.4 2.4e-67 226.3 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CAR30017.1 - 6.9e-28 97.7 0.0 1.3e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase adh_short_C2 PF13561.6 CAR30018.1 - 3.1e-53 180.7 0.0 3.7e-53 180.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR30018.1 - 6.2e-38 130.2 0.1 7.7e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR30018.1 - 4.8e-11 42.9 0.2 1.6e-10 41.2 0.1 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 CAR30018.1 - 6.8e-06 25.7 0.8 0.0001 21.9 0.3 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR30018.1 - 0.00033 19.8 0.3 0.0015 17.6 0.3 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CAR30018.1 - 0.041 13.0 0.0 0.076 12.1 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Catalase PF00199.19 CAR30019.1 - 8.2e-167 555.1 0.0 1.1e-166 554.8 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CAR30019.1 - 1.4e-11 44.4 0.0 5.2e-11 42.6 0.0 2.0 1 0 0 1 1 1 1 Catalase-related immune-responsive OPT PF03169.15 CAR30020.1 - 1.3e-116 390.7 48.6 1.5e-116 390.5 48.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Epimerase PF01370.21 CAR30021.1 - 6.4e-21 74.9 0.0 1e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CAR30021.1 - 5e-11 42.1 0.0 7.2e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CAR30021.1 - 2.4e-10 40.0 0.0 6.7e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 CAR30021.1 - 2.4e-10 40.3 0.0 3.4e-10 39.9 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CAR30021.1 - 1.2e-08 35.0 0.0 2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CAR30021.1 - 7.2e-07 28.6 0.0 1.1e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 CAR30021.1 - 4e-06 26.4 0.0 5.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 CAR30021.1 - 0.00099 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short_C2 PF13561.6 CAR30021.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 CAR30021.1 - 0.0058 16.2 0.0 0.041 13.4 0.1 2.2 3 0 0 3 3 3 1 NmrA-like family Shikimate_DH PF01488.20 CAR30021.1 - 0.0093 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase KR PF08659.10 CAR30021.1 - 0.049 13.5 0.0 0.086 12.8 0.0 1.4 1 1 0 1 1 1 0 KR domain F420_oxidored PF03807.17 CAR30021.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RTA1 PF04479.13 CAR30022.1 - 2.1e-56 190.8 14.3 2.1e-56 190.8 14.3 1.7 2 0 0 2 2 2 1 RTA1 like protein DUF4257 PF14074.6 CAR30022.1 - 0.0038 17.4 5.2 0.16 12.2 0.4 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF4257) DUF4083 PF13314.6 CAR30022.1 - 0.33 10.9 7.7 0.56 10.2 1.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) GNVR PF13807.6 CAR30022.1 - 1.5 8.8 4.2 18 5.3 0.1 3.1 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase Fungal_trans PF04082.18 CAR30023.1 - 4e-19 68.7 0.8 1.3e-18 67.0 1.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR30023.1 - 1.3e-09 38.0 8.2 3.3e-09 36.7 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain A_thal_3526 PF09713.10 CAR30023.1 - 0.14 12.4 0.6 26 5.2 0.0 2.8 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) SnoaL_4 PF13577.6 CAR30024.1 - 2.1e-21 76.4 0.0 2.3e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain LBP_BPI_CETP PF01273.25 CAR30024.1 - 0.027 14.1 0.4 4.3 6.9 0.1 2.1 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain VERL PF11386.8 CAR30024.1 - 0.053 13.7 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Vitelline envelope receptor for lysin DUF4440 PF14534.6 CAR30024.1 - 0.081 13.3 0.0 0.099 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUP PF00674.18 CAR30703.1 - 2.6e-33 114.2 4.1 7.9e-16 58.1 0.1 2.2 2 0 0 2 2 2 2 DUP family HCO3_cotransp PF00955.21 CAR30703.1 - 0.049 12.5 0.0 0.065 12.1 0.0 1.1 1 0 0 1 1 1 0 HCO3- transporter family Aminotran_3 PF00202.21 CAR30704.1 - 1.7e-99 333.3 0.0 3.1e-99 332.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CAR30704.1 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase AAA_26 PF13500.6 CAR30705.1 - 1.6e-37 129.3 0.0 2e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CAR30705.1 - 0.15 12.2 0.0 6.9 6.7 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUP PF00674.18 CAR30706.1 - 1.6e-08 34.6 0.5 1.6e-08 34.6 0.5 2.9 2 1 1 3 3 3 1 DUP family DUF4648 PF15505.6 CAR30707.1 - 0.4 11.6 2.5 0.66 10.9 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4648) DUP PF00674.18 CAR30708.1 - 4.1e-36 123.2 9.6 1.2e-17 63.9 0.0 2.8 2 1 0 2 2 2 2 DUP family LapA_dom PF06305.11 CAR30708.1 - 0.00071 19.3 0.4 0.0017 18.2 0.4 1.6 1 0 0 1 1 1 1 Lipopolysaccharide assembly protein A domain DIOX_N PF14226.6 CAR30709.1 - 1.1e-33 116.5 0.2 7.8e-33 113.7 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CAR30709.1 - 1.8e-14 54.0 0.0 3.2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Aa_trans PF01490.18 CAR30710.1 - 4.7e-29 101.3 41.3 5.7e-29 101.0 41.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUP PF00674.18 CAR30711.1 - 1.3e-27 96.0 0.1 3.1e-15 56.2 0.0 2.4 2 0 0 2 2 2 2 DUP family DUF2315 PF10231.9 CAR30711.1 - 0.088 12.9 0.5 0.14 12.3 0.5 1.3 1 0 0 1 1 1 0 Apoptogenic protein 1 FMN_bind_2 PF04299.12 CAR30712.1 - 3.9e-57 192.6 0.0 4.6e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Aminotran_3 PF00202.21 CAR30713.1 - 3e-81 273.1 0.0 3.8e-81 272.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Peptidase_M16 PF00675.20 CAR30714.1 - 1.5e-21 77.0 0.0 2.5e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CAR30714.1 - 8.6e-06 25.9 0.1 0.00011 22.3 0.1 2.5 2 1 0 2 2 2 1 Peptidase M16 inactive domain Mt_ATP-synt_D PF05873.12 CAR30715.1 - 1.7e-18 66.9 2.9 2.3e-18 66.5 2.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF2408 PF10303.9 CAR30715.1 - 0.048 14.2 1.7 0.073 13.6 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) LTXXQ PF07813.12 CAR30715.1 - 0.05 14.3 0.8 0.45 11.2 0.4 2.0 1 1 1 2 2 2 0 LTXXQ motif family protein Aida_N PF08910.10 CAR30715.1 - 0.12 12.7 1.6 0.23 11.9 1.2 1.7 1 1 0 1 1 1 0 Aida N-terminus Cauli_AT PF03233.13 CAR30715.1 - 0.16 11.9 2.1 0.28 11.1 2.1 1.6 1 1 0 1 1 1 0 Aphid transmission protein Fungal_trans PF04082.18 CAR30716.1 - 3.5e-15 55.8 0.2 7.6e-15 54.7 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR30716.1 - 9.8e-08 32.0 8.4 1.7e-07 31.2 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Npa1 PF11707.8 CAR30717.1 - 1.9e-92 310.3 6.2 7.4e-92 308.3 5.2 2.3 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CAR30717.1 - 2.9e-40 138.0 1.0 6.8e-40 136.8 0.1 2.2 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 HTH_Tnp_1_2 PF13022.6 CAR30717.1 - 0.088 13.0 0.5 69 3.6 0.1 3.5 3 0 0 3 3 3 0 Helix-turn-helix of insertion element transposase DUF5321 PF17254.2 CAR30718.1 - 9.2e-05 21.9 4.0 9.2e-05 21.9 4.0 1.9 1 1 1 2 2 2 1 Family of unknown function (DUF5321) DUF3689 PF12463.8 CAR30718.1 - 0.002 17.5 2.1 0.0026 17.1 1.6 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3689) Fungal_trans PF04082.18 CAR30719.1 - 9e-23 80.6 1.4 9e-23 80.6 1.4 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR30719.1 - 0.00012 22.2 7.1 0.00012 22.2 7.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARPC4 PF05856.12 CAR30720.1 - 3.3e-73 244.8 4.5 3.7e-73 244.6 4.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) TpcC PF12642.7 CAR30720.1 - 0.18 11.6 2.4 2.2 8.0 0.2 2.3 2 1 0 2 2 2 0 Conjugative transposon protein TcpC FF PF01846.19 CAR30721.1 - 4.8e-36 122.7 20.8 3e-13 49.7 0.0 5.9 6 0 0 6 6 6 4 FF domain WW PF00397.26 CAR30721.1 - 1.9e-19 69.4 10.3 1.7e-10 40.8 0.7 2.8 3 0 0 3 3 3 2 WW domain Glyco_hyd_101C PF17451.2 CAR30721.1 - 5e-08 33.2 4.7 0.0015 18.8 0.7 2.9 1 1 1 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain PQQ PF01011.21 CAR30721.1 - 0.002 17.9 0.4 0.024 14.6 0.1 2.3 2 0 0 2 2 2 1 PQQ enzyme repeat WW_1 PF18507.1 CAR30721.1 - 0.025 14.2 0.4 2.6 7.8 0.1 2.8 2 0 0 2 2 2 0 WW domain DUF5601 PF18151.1 CAR30721.1 - 0.063 13.6 1.4 18 5.7 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) RhoGAP-FF1 PF16512.5 CAR30721.1 - 0.18 12.5 10.7 0.4 11.4 3.9 3.5 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain G-gamma PF00631.22 CAR30721.1 - 0.31 11.1 4.1 0.29 11.2 1.2 2.5 2 0 0 2 2 2 0 GGL domain QueH PF02677.14 CAR30721.1 - 1.9 8.6 6.6 0.58 10.2 1.9 2.4 2 0 0 2 2 2 0 Epoxyqueuosine reductase QueH Peptidase_S24 PF00717.23 CAR30722.1 - 2.8e-07 30.4 0.0 4.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Ydc2-catalyt PF09159.10 CAR30723.1 - 7e-53 180.2 0.1 1.1e-52 179.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 CAR30723.1 - 0.016 15.3 0.3 11 6.2 0.0 3.1 2 2 1 3 3 3 0 Poxvirus A22 protein RGS PF00615.19 CAR30723.1 - 0.033 14.5 0.1 0.065 13.5 0.1 1.5 1 0 0 1 1 1 0 Regulator of G protein signaling domain Flavoprotein PF02441.19 CAR30725.1 - 3.5e-52 176.3 0.0 4.9e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein CKAP2_C PF15297.6 CAR30725.1 - 1.4 7.9 11.1 2.9 6.9 11.1 1.4 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus zf-Tim10_DDP PF02953.15 CAR30726.1 - 2.2e-21 75.2 2.8 3e-21 74.8 2.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cyto_heme_lyase PF01265.17 CAR30727.1 - 5.6e-44 150.9 16.1 1.6e-42 146.1 16.1 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase G-alpha PF00503.20 CAR30728.1 - 6e-110 367.7 6.3 7.6e-110 367.4 6.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CAR30728.1 - 1.3e-14 54.1 1.3 6.5e-10 38.7 0.0 2.8 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CAR30728.1 - 0.00076 18.9 0.2 0.077 12.3 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region ParBc PF02195.18 CAR30729.1 - 1.6e-14 53.9 0.0 1.9e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Ldh_1_C PF02866.18 CAR30730.1 - 1.6e-51 174.5 0.0 9.4e-51 172.1 0.2 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CAR30730.1 - 1.8e-43 148.0 0.0 2.6e-43 147.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CAR30730.1 - 0.00019 20.6 0.0 0.00026 20.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family zf-CHY PF05495.12 CAR30731.1 - 4.7e-12 46.2 15.5 6.6e-12 45.8 15.5 1.2 1 0 0 1 1 1 1 CHY zinc finger HypA PF01155.19 CAR30731.1 - 0.2 11.7 9.9 0.57 10.2 6.9 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_C7 PF14522.6 CAR30731.1 - 0.45 10.6 12.5 0.74 9.9 12.5 1.5 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c Ank_2 PF12796.7 CAR30732.1 - 2.8e-21 75.9 0.0 3.4e-09 37.2 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CAR30732.1 - 3.7e-19 68.8 8.0 7.5e-06 26.4 0.1 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CAR30732.1 - 2e-14 53.3 4.9 0.0026 18.1 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CAR30732.1 - 3.7e-12 45.3 3.1 0.015 15.8 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CAR30732.1 - 4.8e-11 42.7 0.4 1.2e-05 25.5 0.0 4.4 3 2 3 6 6 6 3 Ankyrin repeats (many copies) TUG-UBL1 PF11470.8 CAR30733.1 - 4.4e-27 94.1 0.0 1.3e-26 92.5 0.0 1.9 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 CAR30733.1 - 4.8e-15 55.5 0.6 1.4e-14 54.0 0.2 2.0 2 0 0 2 2 2 1 UBX domain UN_NPL4 PF11543.8 CAR30733.1 - 0.018 15.5 0.0 0.26 11.8 0.0 2.4 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 SASP PF00269.20 CAR30733.1 - 0.07 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type PPR_long PF17177.4 CAR30734.1 - 0.011 15.1 0.0 0.16 11.3 0.0 2.4 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CAR30734.1 - 0.013 15.5 3.1 41 4.4 0.4 4.8 4 0 0 4 4 4 0 Pentatricopeptide repeat domain SURF6 PF04935.12 CAR30735.1 - 1.8e-44 151.9 48.8 1.8e-44 151.9 48.8 3.6 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 CAR30735.1 - 5.5e-13 49.3 4.1 5.5e-13 49.3 4.1 7.8 5 3 1 6 6 6 1 60S ribosome biogenesis protein Rrp14 DUF99 PF01949.16 CAR30735.1 - 3 7.2 4.7 5.2 6.4 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF99 EF1G PF00647.19 CAR30736.1 - 8.3e-44 148.0 0.2 1.9e-43 146.9 0.2 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CAR30736.1 - 2.3e-14 53.4 0.1 2.3e-14 53.4 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CAR30736.1 - 3.5e-09 36.9 2.8 4.8e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CAR30736.1 - 1.1e-05 25.7 0.0 2.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CAR30736.1 - 1.2e-05 25.4 0.1 1.2e-05 25.4 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAR30736.1 - 9.2e-05 22.4 0.3 0.00017 21.5 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain V-ATPase_C PF03223.15 CAR30737.1 - 9.6e-121 403.7 0.7 1.1e-120 403.5 0.7 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NUC130_3NT PF08158.12 CAR30737.1 - 0.0025 18.1 0.7 3.1 8.2 0.1 2.6 2 0 0 2 2 2 2 NUC130/3NT domain Kinesin PF00225.23 CAR30738.1 - 2e-59 201.2 10.4 2e-59 201.2 10.4 2.3 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CAR30738.1 - 3.1e-20 72.6 0.0 3.1e-20 72.6 0.0 3.4 4 1 0 4 4 4 1 Microtubule binding AAA_24 PF13479.6 CAR30738.1 - 0.41 10.3 3.5 14 5.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Tht1 PF04163.12 CAR30739.1 - 9.2e-45 153.4 31.7 4.8e-44 151.0 31.7 1.9 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein YojJ PF10372.9 CAR30739.1 - 0.03 14.4 0.2 0.03 14.4 0.2 3.5 2 1 2 4 4 4 0 Bacterial membrane-spanning protein N-terminus PRESAN PF09687.10 CAR30739.1 - 0.13 12.8 20.9 0.36 11.4 2.5 3.2 2 1 1 3 3 3 0 Plasmodium RESA N-terminal CENP-H PF05837.12 CAR30739.1 - 0.62 10.5 6.4 1.7 9.1 3.3 2.7 1 1 0 2 2 2 0 Centromere protein H (CENP-H) Baculo_PEP_C PF04513.12 CAR30739.1 - 6 6.9 20.0 0.32 11.0 3.4 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bcl-2 PF00452.19 CAR30739.1 - 6 7.6 8.3 11 6.8 0.2 3.7 3 3 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family ApoLp-III PF07464.11 CAR30739.1 - 6.7 6.8 18.7 3.5 7.7 6.7 3.3 2 1 2 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF948 PF06103.11 CAR30739.1 - 8.1 6.8 9.4 47 4.3 0.1 4.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) AEP1 PF17049.5 CAR30740.1 - 3.4e-140 467.6 1.6 4.1e-140 467.4 1.6 1.1 1 0 0 1 1 1 1 ATPase expression protein 1 SUR7 PF06687.12 CAR30741.1 - 7.1e-21 74.8 14.4 9.3e-21 74.4 14.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family HA2 PF04408.23 CAR30742.1 - 2.3e-19 69.7 0.0 4.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CAR30742.1 - 1.7e-12 47.6 0.0 5.1e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CAR30742.1 - 3.1e-10 40.3 0.0 6.6e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CAR30742.1 - 1.4e-08 34.7 0.2 2.5e-08 33.9 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CAR30742.1 - 9.2e-06 26.1 0.2 1.7e-05 25.2 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAR30742.1 - 0.00079 19.7 0.3 0.0021 18.3 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CAR30742.1 - 0.0044 16.8 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CAR30742.1 - 0.0075 16.0 0.4 0.027 14.2 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain Flavi_DEAD PF07652.14 CAR30742.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 Flavivirus DEAD domain RsgA_GTPase PF03193.16 CAR30742.1 - 0.041 13.8 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 CAR30742.1 - 0.057 13.6 0.0 0.29 11.3 0.0 2.1 2 1 1 3 3 3 0 AAA domain DUF2075 PF09848.9 CAR30742.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Herpes_Helicase PF02689.14 CAR30742.1 - 0.077 10.9 0.0 0.11 10.4 0.0 1.1 1 0 0 1 1 1 0 Helicase AAA_24 PF13479.6 CAR30742.1 - 0.13 12.0 0.1 0.3 10.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CAR30742.1 - 0.18 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 CAR30742.1 - 0.19 12.2 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CAR30742.1 - 0.28 11.7 0.8 0.73 10.3 0.8 1.7 1 1 0 1 1 1 0 ABC transporter Sugar_tr PF00083.24 CAR30743.1 - 1.2e-114 383.7 25.7 1.5e-114 383.4 25.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR30743.1 - 2e-28 99.4 29.5 1.6e-20 73.3 5.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OppC_N PF12911.7 CAR30743.1 - 0.73 9.9 4.2 0.36 10.9 0.6 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Sugar_tr PF00083.24 CAR30744.1 - 2.6e-117 392.5 27.2 3.2e-117 392.2 27.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR30744.1 - 1.8e-22 79.8 52.1 5.4e-21 74.9 25.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ArgJ PF01960.18 CAR30745.1 - 4.9e-144 479.7 5.6 5.6e-144 479.5 5.6 1.0 1 0 0 1 1 1 1 ArgJ family Suf PF05843.14 CAR30746.1 - 5.7e-63 213.7 17.3 4.7e-56 190.9 6.2 3.6 2 2 1 3 3 3 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CAR30746.1 - 0.0077 17.0 0.0 1.2 10.2 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat Rpn9_C PF18261.1 CAR30746.1 - 0.0079 15.8 0.1 0.021 14.4 0.1 1.7 1 0 0 1 1 1 1 Rpn9 C-terminal helix Viral_Beta_CD PF04530.12 CAR30746.1 - 0.14 12.5 0.1 0.94 9.8 0.0 2.2 2 0 0 2 2 2 0 Viral Beta C/D like family Tom37_C PF11801.8 CAR30747.1 - 1.3e-51 174.4 0.9 1.9e-51 173.9 0.9 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.9 CAR30747.1 - 1e-29 103.4 1.5 1.1e-29 103.3 0.3 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein MIP-T3_C PF17749.1 CAR30747.1 - 0.026 14.5 0.3 0.056 13.4 0.3 1.5 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Sen15 PF09631.10 CAR30748.1 - 8.2e-26 90.2 0.0 9.5e-26 90.0 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein Chromo_shadow PF01393.19 CAR30748.1 - 0.07 13.2 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Chromo shadow domain Ge1_WD40 PF16529.5 CAR30748.1 - 0.099 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4448 PF14610.6 CAR30749.1 - 1.9e-54 184.4 0.4 3e-54 183.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Cu-oxidase_2 PF07731.14 CAR30751.1 - 1.3e-47 161.0 4.9 1.7e-40 137.9 0.3 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CAR30751.1 - 2e-44 150.4 1.9 1.1e-40 138.3 0.6 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CAR30751.1 - 3.4e-34 118.3 6.3 1.1e-33 116.6 0.5 3.5 3 1 0 3 3 3 1 Multicopper oxidase PPC PF04151.15 CAR30751.1 - 0.036 15.2 0.1 1.1 10.5 0.0 3.0 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Cupredoxin_1 PF13473.6 CAR30751.1 - 0.05 13.7 0.0 2 8.5 0.0 3.3 2 2 1 3 3 3 0 Cupredoxin-like domain Mito_carr PF00153.27 CAR30753.1 - 9.7e-69 227.4 5.6 7.9e-25 86.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RabGAP-TBC PF00566.18 CAR30754.1 - 3e-37 128.4 1.1 3e-37 128.4 1.1 1.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RRM_1 PF00076.22 CAR30755.1 - 4.8e-05 23.1 0.0 0.00069 19.4 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.20 CAR30756.1 - 1.3e-53 182.1 0.6 1.3e-53 182.1 0.6 2.3 1 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CAR30756.1 - 0.0016 17.4 0.0 0.01 14.6 0.0 2.2 1 1 0 1 1 1 1 MreB/Mbl protein DUF2120 PF09893.9 CAR30756.1 - 0.0046 17.1 0.3 0.0046 17.1 0.3 3.4 4 0 0 4 4 4 1 Uncharacterized protein conserved in archaea (DUF2120) FAM199X PF15814.5 CAR30756.1 - 0.053 12.6 10.4 0.029 13.4 3.9 2.8 3 0 0 3 3 3 0 Protein family FAM199X DUF1168 PF06658.12 CAR30756.1 - 0.11 12.3 9.7 0.34 10.7 9.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) V_ATPase_I PF01496.19 CAR30757.1 - 7.1e-297 986.8 8.3 1.2e-296 986.0 8.3 1.3 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family CLZ PF16526.5 CAR30757.1 - 0.0055 17.0 0.4 1 9.8 0.0 2.8 2 0 0 2 2 2 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CNP1 PF08750.11 CAR30758.1 - 0.081 12.9 0.3 0.25 11.3 0.3 1.8 1 0 0 1 1 1 0 CNP1-like family PG_binding_1 PF01471.18 CAR30758.1 - 0.17 12.1 0.0 16 5.8 0.0 2.9 3 0 0 3 3 3 0 Putative peptidoglycan binding domain MRP-S34 PF16053.5 CAR30759.1 - 0.029 14.0 0.3 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S34 DUF4051 PF13260.6 CAR30759.1 - 0.17 11.7 0.1 0.3 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Microtub_bd PF16796.5 CAR30759.1 - 0.67 9.9 8.5 4.7 7.1 0.6 2.7 1 1 2 3 3 3 0 Microtubule binding ABC1 PF03109.16 CAR30760.1 - 1.9e-36 124.8 0.0 3.6e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family OB_NTP_bind PF07717.16 CAR30761.1 - 1.1e-22 80.2 0.0 4.8e-22 78.1 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CAR30761.1 - 4.2e-21 75.3 1.7 4.9e-21 75.0 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CAR30761.1 - 1.6e-10 41.3 0.0 4e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CAR30761.1 - 1.8e-09 37.6 0.2 3.7e-09 36.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CAR30761.1 - 1.1e-06 29.0 0.2 3.2e-06 27.5 0.1 1.8 2 0 0 2 2 1 1 AAA domain SRP54 PF00448.22 CAR30761.1 - 2.4e-05 24.1 0.1 8.3e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CAR30761.1 - 0.001 19.4 0.1 0.0022 18.3 0.1 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CAR30761.1 - 0.0017 18.4 0.1 0.0035 17.3 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 CAR30761.1 - 0.0018 18.0 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CAR30761.1 - 0.011 16.3 0.0 0.12 12.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CAR30761.1 - 0.034 13.4 0.0 0.066 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 CAR30761.1 - 0.047 12.8 0.0 0.096 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CAR30761.1 - 0.057 12.9 0.0 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region cwf21 PF08312.12 CAR30762.1 - 0.033 14.3 0.0 0.18 12.0 0.0 2.1 1 1 0 1 1 1 0 cwf21 domain Nab2 PF11517.8 CAR30763.1 - 9.6e-48 160.7 2.8 1.5e-47 160.1 2.8 1.2 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.6 CAR30763.1 - 3.9e-21 74.7 72.7 1.2e-05 25.6 5.7 7.3 7 0 0 7 7 7 7 RNA-binding, Nab2-type zinc finger Nab2p_Zf1 PF18260.1 CAR30763.1 - 4.5e-17 61.6 8.1 4.5e-17 61.6 8.1 3.2 3 0 0 3 3 3 1 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 DUF2508 PF10704.9 CAR30763.1 - 0.02 15.0 0.2 0.041 14.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Roughex PF06020.11 CAR30763.1 - 2.7 7.0 6.6 5.4 6.0 6.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Ribosomal_S5 PF00333.20 CAR30764.1 - 7.9e-26 89.8 2.5 1.7e-25 88.8 2.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CAR30764.1 - 1.1e-22 79.2 0.0 1.9e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Apolipoprotein PF01442.18 CAR30765.1 - 2.4e-05 24.3 3.1 2.8e-05 24.1 3.1 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF5353 PF17304.2 CAR30765.1 - 0.02 14.6 0.7 0.035 13.9 0.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5353) DUF2104 PF09877.9 CAR30765.1 - 0.022 15.0 0.2 0.029 14.6 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2104) DUF3549 PF12069.8 CAR30765.1 - 0.11 11.5 0.4 0.14 11.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) SCAB_CC PF16712.5 CAR30765.1 - 0.13 12.0 3.0 0.18 11.6 3.0 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein DUF737 PF05300.11 CAR30765.1 - 0.77 10.1 5.8 0.9 9.9 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF883 PF05957.13 CAR30765.1 - 6.3 7.5 10.6 35 5.1 10.6 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 CAR30765.1 - 8.8 6.4 11.0 20 5.3 11.0 1.6 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Mon1 PF03164.14 CAR30766.1 - 2e-144 481.6 0.5 2.4e-144 481.3 0.5 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 GATA PF00320.27 CAR30767.1 - 7.4e-16 57.5 3.0 1.7e-15 56.3 3.0 1.7 1 0 0 1 1 1 1 GATA zinc finger Glyco_hydro_31 PF01055.26 CAR30768.1 - 6e-121 404.7 1.0 9.3e-121 404.1 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CAR30768.1 - 4e-19 68.7 2.6 1.4e-18 67.0 0.0 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 CAR30768.1 - 7.8e-05 22.9 0.0 0.00033 20.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) Glyco_hydro_31 PF01055.26 CAR30769.1 - 1.3e-122 410.2 0.1 2.3e-122 409.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CAR30769.1 - 6.7e-23 80.8 0.5 8.5e-22 77.3 0.2 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 CAR30769.1 - 9e-07 29.1 0.1 3.6e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) GIY-YIG PF01541.24 CAR30770.1 - 4.8e-12 46.0 0.1 1e-11 45.0 0.1 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 CAR30770.1 - 0.00029 21.0 2.8 0.00064 19.8 2.8 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CAR30770.1 - 0.44 10.6 3.9 1.8 8.6 3.9 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger YacG PF03884.14 CAR30770.1 - 2.8 7.7 6.5 12 5.7 0.1 2.9 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG zf-RING_2 PF13639.6 CAR30770.1 - 9.7 6.6 8.9 0.93 9.9 4.1 1.9 2 0 0 2 2 2 0 Ring finger domain AAA_2 PF07724.14 CAR30771.1 - 1.4e-35 122.9 0.6 3.1e-35 121.8 0.6 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CAR30771.1 - 8.7e-14 52.1 0.3 1.5e-13 51.3 0.3 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CAR30771.1 - 7.6e-08 32.3 0.0 2.1e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CAR30771.1 - 3.5e-07 30.3 0.1 1.1e-06 28.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CAR30771.1 - 5.2e-06 26.0 0.2 0.0019 17.6 0.1 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CAR30771.1 - 0.00016 22.0 1.0 0.0068 16.7 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CAR30771.1 - 0.0014 18.8 0.1 0.021 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 CAR30771.1 - 0.0018 18.0 0.7 0.025 14.3 0.2 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CAR30771.1 - 0.004 16.9 0.0 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 CAR30771.1 - 0.0046 16.7 0.0 0.41 10.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 CAR30771.1 - 0.0073 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 CAR30771.1 - 0.012 15.7 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CAR30771.1 - 0.013 15.2 0.8 0.072 12.8 0.8 2.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CAR30771.1 - 0.049 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 CAR30771.1 - 0.098 13.0 0.0 0.32 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 CAR30771.1 - 0.11 12.9 0.3 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Androgen_recep PF02166.16 CAR30771.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Androgen receptor DEAD PF00270.29 CAR30771.1 - 0.16 11.7 3.6 1.3 8.8 0.1 3.3 3 1 0 4 4 4 0 DEAD/DEAH box helicase zf-Mss51 PF13824.6 CAR30771.1 - 0.19 11.8 0.0 0.45 10.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Methyltransf_11 PF08241.12 CAR30772.1 - 3.6e-06 27.5 0.0 8.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR30772.1 - 0.0024 17.7 0.0 0.005 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR30772.1 - 0.0035 18.0 0.0 0.011 16.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_60s PF00428.19 CAR30772.1 - 0.76 10.4 3.4 16 6.1 3.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein MTHFR PF02219.17 CAR30773.1 - 9.3e-119 396.0 0.0 1.2e-118 395.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Tyr-DNA_phospho PF06087.12 CAR30775.1 - 5e-95 318.9 1.5 5.7e-95 318.7 1.5 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 CAR30775.1 - 0.019 14.9 0.0 0.083 12.8 0.0 1.9 2 0 0 2 2 2 0 PLD-like domain AMP-binding PF00501.28 CAR30776.1 - 4.5e-74 249.5 0.0 6.1e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CAR30776.1 - 8.9e-19 68.2 3.5 1.9e-18 67.2 0.2 2.9 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Mito_carr PF00153.27 CAR30777.1 - 5.9e-50 167.2 6.5 3.6e-17 62.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_transf_15 PF01793.16 CAR30778.1 - 4.9e-122 407.2 8.5 6.1e-122 406.9 8.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Staygreen PF12638.7 CAR30778.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Staygreen protein Nucleoporin_FG PF13634.6 CAR30779.1 - 4.5e-05 24.2 29.3 0.0002 22.2 12.3 8.4 1 1 8 9 9 9 3 Nucleoporin FG repeat region Ribosomal_S7e PF01251.18 CAR30781.1 - 1.9e-79 265.7 1.5 2.2e-79 265.5 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Rib_5-P_isom_A PF06026.14 CAR30782.1 - 2.6e-57 193.2 0.0 3.5e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CAR30782.1 - 0.028 14.4 0.0 7.5 6.5 0.0 2.3 2 0 0 2 2 2 0 DeoR C terminal sensor domain Arf PF00025.21 CAR30783.1 - 3.7e-71 238.2 0.2 4.2e-71 238.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CAR30783.1 - 5.8e-16 58.8 0.1 8.2e-16 58.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CAR30783.1 - 2.4e-14 53.2 0.0 2.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CAR30783.1 - 6.1e-14 51.9 0.8 3.1e-09 36.5 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CAR30783.1 - 7.3e-14 51.7 0.0 8.5e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CAR30783.1 - 2.5e-10 40.1 0.0 3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CAR30783.1 - 4.3e-06 26.8 0.0 6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CAR30783.1 - 0.15 11.3 0.4 0.26 10.6 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AMP-binding PF00501.28 CAR30784.1 - 2.5e-37 128.5 0.0 7.6e-14 51.1 0.0 4.7 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.11 CAR30784.1 - 7.7e-11 42.8 0.1 2.8e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 DMAP1-binding Domain Mem_trans PF03547.18 CAR30785.1 - 4.5e-26 91.2 0.0 7.7e-26 90.4 0.0 1.4 1 1 0 1 1 1 1 Membrane transport protein Sugar_tr PF00083.24 CAR30786.1 - 9.4e-79 265.4 27.5 1.1e-78 265.1 27.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR30786.1 - 3.1e-12 46.1 34.3 3.1e-12 46.1 34.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0715 PF17094.5 CAR30786.1 - 0.77 10.3 5.5 0.44 11.1 2.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0715) 4HBT PF03061.22 CAR30787.1 - 1.4e-05 25.4 0.0 2.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Asp PF00026.23 CAR30788.1 - 5.2e-69 233.1 2.8 1.6e-68 231.5 2.8 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CAR30788.1 - 1.5e-10 41.6 0.8 1.7e-09 38.2 0.8 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 CAR30788.1 - 0.00034 21.1 0.1 1.2 9.7 0.0 3.7 4 0 0 4 4 4 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CAR30788.1 - 0.00078 20.0 0.3 2.4 8.9 0.0 3.3 3 0 0 3 3 3 2 Aspartyl protease MFS_1 PF07690.16 CAR30789.1 - 9.3e-30 103.7 16.3 9.3e-30 103.7 16.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 CAR30789.1 - 1.8e-05 24.2 0.9 1.8e-05 24.2 0.9 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF5325 PF17259.2 CAR30789.1 - 8.4 6.4 10.1 14 5.6 0.3 4.1 3 0 0 3 3 3 0 Family of unknown function (DUF5325) ArfGap PF01412.18 CAR30790.1 - 4.8e-33 113.7 1.1 4.8e-33 113.7 1.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Rox3 PF08633.10 CAR30791.1 - 4.6e-36 125.0 0.2 6.1e-36 124.6 0.2 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit Pkinase PF00069.25 CAR30793.1 - 2.8e-17 63.0 0.0 1.6e-16 60.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30793.1 - 4.2e-08 32.8 0.0 6.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CAR30793.1 - 1.4e-05 24.1 0.0 2.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase KHA PF11834.8 CAR30793.1 - 0.15 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel Peptidase_M44 PF03410.13 CAR30793.1 - 0.21 10.2 0.0 0.34 9.4 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox MRG PF05712.13 CAR30794.1 - 1.4e-38 132.2 1.0 1.4e-38 132.2 1.0 1.6 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.8 CAR30794.1 - 1.5e-06 28.0 0.2 1.5e-06 28.0 0.2 2.1 2 1 0 2 2 2 1 RNA binding activity-knot of a chromodomain Coilin_N PF15862.5 CAR30794.1 - 1 9.1 6.8 7.6 6.3 6.8 2.3 1 1 0 1 1 1 0 Coilin N-terminus Mito_carr PF00153.27 CAR30795.1 - 9.6e-72 237.0 0.5 3.8e-24 84.4 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Bud13 PF09736.9 CAR30797.1 - 8.2e-22 78.2 7.1 1.3e-19 71.1 0.5 3.9 2 2 1 3 3 3 2 Pre-mRNA-splicing factor of RES complex AAA_28 PF13521.6 CAR30797.1 - 0.076 13.2 0.2 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain MDFI PF15316.6 CAR30797.1 - 8.2 6.5 14.8 1.9 8.6 3.9 2.3 2 0 0 2 2 2 0 MyoD family inhibitor XRN_N PF03159.18 CAR30798.1 - 1.9e-94 315.7 0.0 3.9e-94 314.6 0.0 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CAR30798.1 - 1e-91 308.1 6.5 1e-91 308.1 6.5 2.4 2 1 1 3 3 3 1 Xrn1 helical domain XRN1_D1 PF18332.1 CAR30798.1 - 1.7e-60 204.1 3.4 6.1e-60 202.3 0.0 2.8 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 CAR30798.1 - 2.5e-30 104.5 0.2 1.1e-29 102.4 0.0 2.3 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain Xrn1_D3 PF18194.1 CAR30798.1 - 1.9e-25 88.7 1.7 5.8e-25 87.2 1.7 1.9 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 SH3_12 PF18129.1 CAR30798.1 - 1.3e-19 70.0 0.1 2.7e-19 69.0 0.1 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Nucleoporin_FG PF13634.6 CAR30799.1 - 5.1e-30 104.2 225.2 4.3e-11 43.5 49.9 5.7 2 1 6 8 8 8 7 Nucleoporin FG repeat region DUF1664 PF07889.12 CAR30799.1 - 0.67 10.0 3.4 7 6.7 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DEAD PF00270.29 CAR30800.1 - 6.2e-42 143.3 0.2 1.3e-41 142.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR30800.1 - 6.4e-32 110.2 1.3 1.3e-27 96.4 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30800.1 - 2.6e-05 24.3 0.3 0.00013 22.1 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.14 CAR30800.1 - 0.031 13.1 0.3 4.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer DUF2681 PF10883.8 CAR30800.1 - 0.38 11.2 2.0 1.3 9.5 1.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) ATP-synt_G PF04718.15 CAR30801.1 - 2.4e-29 102.1 0.2 2.9e-29 101.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit MCM PF00493.23 CAR30802.1 - 3.1e-101 337.1 0.0 4.8e-101 336.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CAR30802.1 - 1.2e-36 125.3 0.5 2.4e-36 124.4 0.5 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CAR30802.1 - 1.7e-29 102.0 3.8 8.3e-29 99.9 1.8 2.8 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 CAR30802.1 - 6.9e-19 68.4 3.4 3e-18 66.3 3.4 2.2 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 CAR30802.1 - 3.9e-06 26.9 0.3 3.4e-05 23.9 0.0 2.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CAR30802.1 - 1.6e-05 24.4 0.0 0.00053 19.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CAR30802.1 - 0.001 19.0 0.0 0.0077 16.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAR30802.1 - 0.064 13.6 2.0 3.6 7.9 0.1 3.3 3 1 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.26 CAR30802.1 - 0.076 12.7 0.2 3.4 7.4 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain PXT1 PF15214.6 CAR30802.1 - 0.12 12.7 0.1 0.34 11.3 0.1 1.8 1 0 0 1 1 1 0 Peroxisomal testis-specific protein 1 CAF1A PF12253.8 CAR30803.1 - 6.8e-22 77.4 8.7 6.8e-22 77.4 8.7 5.2 3 2 0 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 CAR30803.1 - 0.00046 19.9 67.7 0.00046 19.9 67.7 2.8 2 1 1 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4364 PF14277.6 CAR30804.1 - 0.0066 16.2 2.8 0.015 15.0 2.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) Sod_Fe_N PF00081.22 CAR30804.1 - 0.26 11.8 0.0 0.26 11.8 0.0 2.8 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Nop25 PF09805.9 CAR30804.1 - 0.36 11.3 10.6 0.36 11.3 3.4 2.6 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF4021 PF13213.6 CAR30804.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4021) Cob_adeno_trans PF01923.18 CAR30804.1 - 4.2 7.5 6.3 2.7 8.1 0.2 2.8 3 1 0 3 3 3 0 Cobalamin adenosyltransferase eIF-6 PF01912.18 CAR30805.1 - 3.7e-82 274.5 0.4 4.7e-82 274.2 0.4 1.1 1 0 0 1 1 1 1 eIF-6 family zf-C2H2 PF00096.26 CAR30806.1 - 3.9e-09 36.5 10.5 0.00036 20.8 1.5 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CAR30806.1 - 4.6e-07 30.1 9.7 0.0054 17.5 1.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CAR30806.1 - 1.5e-05 25.2 9.2 0.00013 22.3 0.5 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 CAR30806.1 - 0.0002 21.6 6.4 0.012 16.0 0.3 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CAR30806.1 - 0.00054 20.2 4.5 0.18 12.1 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CAR30806.1 - 0.013 16.1 0.8 0.013 16.1 0.8 2.4 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 CAR30806.1 - 0.25 11.1 7.8 2.6 7.9 0.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 CAR30806.1 - 0.53 10.6 5.6 1.4 9.3 0.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CAR30806.1 - 1.7 8.7 7.3 3 8.0 1.6 2.3 1 1 1 2 2 2 0 BED zinc finger Mito_carr PF00153.27 CAR30807.1 - 8e-73 240.5 2.7 2.3e-26 91.5 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CAR30807.1 - 0.015 14.5 2.9 14 4.8 0.0 3.8 2 1 1 4 4 4 0 Gammaproteobacterial serine protease DUF3764 PF12594.8 CAR30807.1 - 0.2 11.8 0.0 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) B12D PF06522.11 CAR30808.1 - 0.0024 17.6 0.2 0.0039 17.0 0.2 1.4 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Xan_ur_permease PF00860.20 CAR30809.1 - 2.8e-60 204.1 25.7 4.3e-60 203.4 25.7 1.2 1 0 0 1 1 1 1 Permease family RNA_pol_Rpb2_6 PF00562.28 CAR30810.1 - 5.6e-113 377.9 0.0 1.1e-112 377.0 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CAR30810.1 - 2.3e-45 154.6 0.0 3.2e-45 154.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CAR30810.1 - 9e-34 116.8 0.0 1.7e-33 115.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 CAR30810.1 - 5e-28 97.1 0.0 1.3e-27 95.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CAR30810.1 - 4.8e-22 77.7 0.0 1.2e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 CAR30810.1 - 1.3e-16 60.8 0.0 4.9e-15 55.7 0.0 2.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 E1-E2_ATPase PF00122.20 CAR30811.1 - 7.9e-50 168.9 0.1 7.9e-50 168.9 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CAR30811.1 - 4.8e-47 160.0 1.7 4.8e-47 160.0 1.7 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CAR30811.1 - 5.8e-21 75.7 0.0 5.9e-20 72.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CAR30811.1 - 2.7e-18 65.8 0.1 5.9e-18 64.7 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CAR30811.1 - 3.6e-14 52.2 0.0 3.3e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAR30811.1 - 0.00028 20.7 0.8 0.003 17.4 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CAR30811.1 - 0.15 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sua5_yciO_yrdC PF01300.18 CAR30812.1 - 2e-48 164.3 0.0 3e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CAR30812.1 - 2.9e-30 105.6 0.0 4.2e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF928 PF06051.12 CAR30812.1 - 0.14 12.0 0.2 0.31 10.9 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) Uteroglobin PF01099.17 CAR30813.1 - 0.0034 17.7 0.1 0.0049 17.2 0.1 1.3 1 0 0 1 1 1 1 Uteroglobin family APP_E2 PF12925.7 CAR30813.1 - 0.013 15.2 0.1 0.017 14.8 0.1 1.1 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein DUF4320 PF14208.6 CAR30813.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) CDC27 PF09507.10 CAR30814.1 - 9e-06 25.3 43.3 5e-05 22.9 41.1 2.4 2 1 0 2 2 2 2 DNA polymerase subunit Cdc27 ATP-synt_C PF00137.21 CAR30815.1 - 2.1e-33 114.4 31.2 1.4e-21 76.6 11.2 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 CAR30815.1 - 1.6 8.6 9.6 1.9 8.4 2.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Nucleopor_Nup85 PF07575.13 CAR30816.1 - 2.8e-192 640.3 8.5 3.3e-192 640.1 8.5 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Urb2 PF10441.9 CAR30817.1 - 1.3e-54 185.2 2.9 2.2e-54 184.5 0.8 2.5 2 0 0 2 2 2 1 Urb2/Npa2 family DUF257 PF03192.13 CAR30817.1 - 0.019 14.8 4.3 0.11 12.3 0.2 2.8 3 0 0 3 3 3 0 Pyrococcus protein of unknown function, DUF257 Gag_p15 PF08723.10 CAR30817.1 - 0.046 13.9 0.2 7.2 6.8 0.0 3.5 2 1 0 3 3 3 0 Gag protein p15 Voltage_CLC PF00654.20 CAR30818.1 - 4.3e-77 259.8 23.7 4.3e-77 259.8 23.7 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CAR30818.1 - 2.2e-14 53.6 0.8 1.8e-08 34.7 0.0 3.3 3 0 0 3 3 3 2 CBS domain Ribosomal_L7Ae PF01248.26 CAR30819.1 - 8.2e-27 92.8 0.0 9.8e-27 92.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CAR30819.1 - 0.0021 17.9 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CAR30819.1 - 0.0068 16.5 0.0 0.0076 16.3 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF2229 PF09989.9 CAR30819.1 - 0.09 12.4 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) ANAPC4_WD40 PF12894.7 CAR30820.1 - 0.065 13.5 0.0 11 6.4 0.0 3.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 CAR30821.1 - 0.0046 16.3 0.1 0.014 14.7 0.1 1.8 2 0 0 2 2 2 1 CPSF A subunit region HECT PF00632.25 CAR30822.1 - 3.6e-79 266.4 0.3 7.2e-79 265.5 0.3 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3199 PF11436.8 CAR30822.1 - 0.13 12.2 0.1 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3199) zf-LSD1 PF06943.12 CAR30822.1 - 0.15 11.9 8.4 0.047 13.5 4.6 2.2 3 0 0 3 3 3 0 LSD1 zinc finger Rieske PF00355.26 CAR30823.1 - 3.7e-11 42.8 0.0 6.7e-11 42.0 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CAR30823.1 - 2.7e-10 40.6 0.9 1.2e-09 38.5 0.8 2.1 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region DUF2235 PF09994.9 CAR30824.1 - 4e-80 269.2 0.0 5.8e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) RecG_N PF17190.4 CAR30824.1 - 0.8 10.5 3.2 0.66 10.7 0.2 2.3 2 1 0 2 2 2 0 RecG N-terminal helical domain SNF2_N PF00176.23 CAR30825.1 - 3.4e-74 249.6 0.0 5.8e-74 248.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CAR30825.1 - 5.1e-21 75.1 0.0 1.8e-20 73.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30825.1 - 1.3e-06 28.5 0.1 7e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pet191_N PF10203.9 CAR30826.1 - 9e-23 80.4 3.5 1.4e-22 79.7 3.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 CAR30826.1 - 0.67 10.0 5.1 6 7.0 0.3 3.0 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CAR30826.1 - 1.7 8.9 6.7 2.6 8.3 1.1 2.8 3 1 0 3 3 3 0 CHCH domain Rav1p_C PF12234.8 CAR30827.1 - 1.3e-248 826.7 1.5 1.3e-248 826.7 1.5 2.0 2 0 0 2 2 2 1 RAVE protein 1 C terminal Pro_isomerase PF00160.21 CAR30828.1 - 2e-41 141.9 0.0 4.6e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CAR30828.1 - 1e-08 34.6 12.4 0.00012 21.9 0.8 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CAR30828.1 - 2.8e-06 26.9 1.0 2.8e-06 26.9 1.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CAR30828.1 - 5.4e-06 26.6 1.6 0.00043 20.5 1.6 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CAR30828.1 - 0.018 15.7 0.6 0.059 14.0 0.6 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CAR30828.1 - 0.022 14.8 4.5 0.047 13.8 1.7 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CAR30828.1 - 0.04 13.8 1.2 9.8 6.2 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAR30828.1 - 0.051 13.6 2.8 4.1 7.6 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CAR30828.1 - 0.14 12.8 7.7 0.29 11.9 0.2 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat MIT PF04212.18 CAR30828.1 - 1.7 8.8 11.5 0.6 10.2 0.7 3.2 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 CAR30828.1 - 4.4 7.8 17.0 1.6 9.2 1.5 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Sec7 PF01369.20 CAR30829.1 - 1.8e-68 229.8 1.2 5.4e-68 228.3 1.2 1.9 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CAR30829.1 - 3.5e-14 53.0 0.8 3.5e-14 53.0 0.8 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CAR30829.1 - 4.7e-05 23.1 2.4 4.7e-05 23.1 2.4 3.6 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 MSA-2c PF12238.8 CAR30829.1 - 0.88 9.5 6.8 1.2 9.1 4.9 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c Mito_carr PF00153.27 CAR30830.1 - 5.5e-14 51.9 0.0 2.6e-10 40.1 0.0 2.7 2 0 0 2 2 2 2 Mitochondrial carrier protein OMPdecase PF00215.24 CAR30831.1 - 2.6e-77 259.4 0.0 3e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family zf-Tim10_DDP PF02953.15 CAR30832.1 - 3.6e-21 74.6 3.7 4.7e-21 74.2 3.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger MFS_1 PF07690.16 CAR30833.1 - 5.6e-28 97.9 9.1 9.1e-23 80.7 0.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR30833.1 - 1.3e-09 37.4 3.7 1.3e-09 37.4 3.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CAR30833.1 - 0.0015 17.1 0.3 0.0026 16.3 0.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPP_enzyme_N PF02776.18 CAR30834.1 - 6.8e-43 146.3 0.0 6.4e-42 143.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CAR30834.1 - 9.9e-29 99.8 0.0 1.7e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CAR30834.1 - 7.2e-22 77.8 0.0 2e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF1601 PF07671.11 CAR30834.1 - 1.2 9.1 3.4 0.37 10.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1601) tRNA-synt_2 PF00152.20 CAR30835.1 - 9.9e-78 261.4 0.0 1.2e-77 261.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAR30835.1 - 4.2e-08 33.1 0.0 7.8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CAR30835.1 - 0.16 11.4 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) zf-Nse PF11789.8 CAR30836.1 - 2e-20 72.3 0.3 5.2e-20 71.0 0.3 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CAR30836.1 - 0.00015 21.7 2.3 0.00015 21.7 2.3 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CAR30836.1 - 0.001 18.9 0.3 0.0026 17.5 0.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR30836.1 - 0.0048 17.2 0.9 0.017 15.5 0.9 2.0 1 0 0 1 1 1 1 Ring finger domain zf-MIZ PF02891.20 CAR30836.1 - 0.016 15.0 1.0 0.034 13.9 0.1 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.25 CAR30836.1 - 0.035 14.0 0.3 0.09 12.7 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 CAR30836.1 - 0.056 13.6 0.1 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 U-box domain IF-2B PF01008.17 CAR30836.1 - 0.18 11.0 0.4 0.25 10.5 0.4 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF1548 PF07579.11 CAR30836.1 - 0.2 12.0 1.8 5.4 7.3 1.2 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1548) Phosphodiest PF01663.22 CAR30839.1 - 5.4e-68 230.2 0.5 6.8e-68 229.8 0.5 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CAR30839.1 - 0.00084 18.8 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Sulfatase KH_7 PF17214.3 CAR30839.1 - 0.043 13.8 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 KH domain adh_short_C2 PF13561.6 CAR30840.1 - 1.1e-46 159.3 0.1 1.8e-44 152.0 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CAR30840.1 - 2.9e-34 118.3 0.6 2.6e-32 111.9 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CAR30840.1 - 1.5e-12 47.8 0.1 3.1e-11 43.5 0.0 2.1 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 CAR30840.1 - 4.8e-06 25.9 0.0 6.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 CAR30840.1 - 9.1e-05 22.0 0.1 0.00019 21.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAR30840.1 - 0.00075 19.0 0.0 0.0015 18.0 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CAR30840.1 - 0.011 14.9 0.1 0.034 13.3 0.1 1.9 2 1 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 CAR30840.1 - 0.015 14.4 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.22 CAR30841.1 - 1e-42 145.5 0.1 1.3e-42 145.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR30841.1 - 1.6e-16 60.6 0.0 2.3e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR30841.1 - 3.3e-12 46.2 0.0 4.2e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CAR30841.1 - 8.1e-09 35.3 0.2 2e-06 27.5 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CAR30841.1 - 1.6e-05 24.9 0.0 2.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 CAR30841.1 - 0.001 19.1 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 CAR30841.1 - 0.0029 17.1 0.0 0.0041 16.6 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CAR30841.1 - 0.0065 16.0 0.0 0.021 14.3 0.1 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF1904 PF08921.11 CAR30841.1 - 0.029 14.7 0.0 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) ATPase_2 PF01637.18 CAR30841.1 - 0.062 13.2 0.3 0.16 11.9 0.3 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1_Xtn PF16897.5 CAR30841.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain TniB PF05621.11 CAR30841.1 - 0.16 11.4 0.0 0.36 10.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein YjeF_N PF03853.15 CAR30842.1 - 3.2e-31 108.5 0.0 7.8e-31 107.3 0.0 1.7 2 0 0 2 2 2 1 YjeF-related protein N-terminus FDF PF09532.10 CAR30842.1 - 1.5e-07 32.2 13.6 4.4e-07 30.7 13.6 1.8 1 1 0 1 1 1 1 FDF domain Gar1 PF04410.14 CAR30842.1 - 0.038 13.7 1.5 0.087 12.6 1.5 1.5 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region DUF150_C PF17384.2 CAR30842.1 - 0.15 12.2 0.9 0.46 10.6 0.2 2.2 2 0 0 2 2 2 0 RimP C-terminal SH3 domain Arm PF00514.23 CAR30843.1 - 4.7e-70 229.7 30.3 4.7e-11 42.3 0.0 10.6 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CAR30843.1 - 1.8e-18 66.7 17.1 0.00029 21.3 0.1 7.9 6 2 2 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.6 CAR30843.1 - 7.9e-16 58.2 9.3 0.0007 19.9 0.1 7.1 3 2 5 8 8 8 4 HEAT repeats Arm_2 PF04826.13 CAR30843.1 - 2.3e-11 43.7 4.7 7.8e-08 32.1 2.8 2.5 1 1 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 CAR30843.1 - 4.7e-11 41.9 14.5 4.4e-07 28.8 2.1 3.5 1 1 2 3 3 3 2 Adaptin N terminal region KAP PF05804.12 CAR30843.1 - 7.6e-11 40.9 0.4 3.3e-10 38.8 0.5 1.9 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT PF02985.22 CAR30843.1 - 6.9e-10 38.3 29.5 0.062 13.6 0.2 10.1 12 0 0 12 12 10 3 HEAT repeat V-ATPase_H_C PF11698.8 CAR30843.1 - 2.5e-05 24.4 3.2 0.14 12.2 0.1 4.8 4 2 3 7 7 7 2 V-ATPase subunit H DUF3361 PF11841.8 CAR30843.1 - 3.5e-05 23.8 6.5 0.011 15.7 0.2 4.3 2 1 2 5 5 5 1 Domain of unknown function (DUF3361) V-ATPase_H_N PF03224.14 CAR30843.1 - 7e-05 22.3 1.2 0.0025 17.2 0.4 3.1 1 1 1 2 2 2 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.7 CAR30843.1 - 0.00028 21.4 0.3 0.88 10.2 0.0 3.7 3 2 1 4 4 2 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CAR30843.1 - 0.00034 20.7 13.4 0.47 10.5 0.1 5.2 2 2 4 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 CAR30843.1 - 0.00073 19.2 0.1 0.036 13.6 0.0 2.8 3 0 0 3 3 3 1 Tti2 family Proteasom_PSMB PF10508.9 CAR30843.1 - 0.0056 15.3 1.5 4.1 5.8 0.0 3.2 1 1 2 3 3 3 1 Proteasome non-ATPase 26S subunit UNC45-central PF11701.8 CAR30843.1 - 0.02 14.8 8.5 4.9 7.1 0.0 4.8 4 2 1 5 5 5 0 Myosin-binding striated muscle assembly central RIF5_SNase_1 PF18187.1 CAR30843.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 TbRIF5 SNase domain 1 RIX1 PF08167.12 CAR30843.1 - 0.059 13.1 0.1 1.9 8.2 0.1 2.9 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis WAPL PF07814.13 CAR30843.1 - 0.15 10.9 7.1 0.18 10.6 0.2 2.9 2 1 1 3 3 3 0 Wings apart-like protein regulation of heterochromatin Uma2 PF05685.12 CAR30843.1 - 0.18 11.4 0.0 0.62 9.6 0.0 1.8 2 0 0 2 2 2 0 Putative restriction endonuclease PfkB PF00294.24 CAR30844.1 - 3.8e-09 36.3 0.0 5e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TENA_THI-4 PF03070.16 CAR30845.1 - 2e-09 37.6 1.0 2.9e-09 37.0 1.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family LSM PF01423.22 CAR30846.1 - 8.9e-11 41.3 0.1 1.1e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 LSM domain DUF4976 PF16347.5 CAR30847.1 - 0.051 13.8 0.3 0.055 13.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) UQ_con PF00179.26 CAR30848.1 - 1.3e-40 138.3 0.1 1.6e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAR30848.1 - 0.029 14.6 1.6 0.038 14.3 0.5 1.9 1 1 0 1 1 1 0 RWD domain Vfa1 PF08432.10 CAR30848.1 - 0.38 11.1 4.6 0.52 10.6 4.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 CAR30848.1 - 0.39 9.0 11.0 0.41 8.9 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 CAR30848.1 - 0.57 10.2 7.2 0.87 9.6 7.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 CAR30848.1 - 3.6 6.8 21.7 4.8 6.4 21.7 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 CAR30848.1 - 8.5 6.0 7.9 14 5.3 7.9 1.4 1 0 0 1 1 1 0 FAM176 family Alpha-amylase_C PF02806.18 CAR30849.1 - 2.7e-25 88.7 0.1 1.2e-24 86.6 0.1 2.2 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CAR30849.1 - 4.2e-19 68.7 0.5 1.4e-18 67.0 0.1 2.1 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CAR30849.1 - 5.6e-14 52.5 1.2 2.3e-13 50.4 0.1 2.4 2 1 1 3 3 3 1 Alpha amylase, catalytic domain Glyco_hydro_66 PF13199.6 CAR30849.1 - 0.011 14.5 0.0 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 AMPK1_CBM PF16561.5 CAR30849.1 - 0.066 13.4 0.1 0.46 10.7 0.0 2.2 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase Frag1 PF10277.9 CAR30850.1 - 2.3e-26 92.7 8.7 2.3e-26 92.7 8.7 3.9 3 1 0 3 3 3 2 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 CAR30850.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Swm2 PF17083.5 CAR30851.1 - 1.1e-35 122.5 1.2 3e-35 121.1 1.2 1.6 1 1 0 1 1 1 1 Nucleolar protein Swm2 Sugar_tr PF00083.24 CAR30852.1 - 1.4e-108 363.6 22.7 1.9e-108 363.2 22.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CAR30852.1 - 5.4e-30 104.5 32.5 1.2e-26 93.5 17.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CAR30852.1 - 0.0014 17.1 1.3 0.0024 16.3 1.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2105 PF09878.9 CAR30852.1 - 0.028 14.2 0.5 0.028 14.2 0.5 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2105) DUF4131 PF13567.6 CAR30852.1 - 6.4 6.4 10.6 22 4.6 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) DUF2373 PF10180.9 CAR30853.1 - 2.5e-25 88.1 0.6 5.7e-25 86.9 0.6 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) HAD PF12710.7 CAR30854.1 - 1.8e-06 28.5 0.0 8.7e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DNA_pol_B_thumb PF14791.6 CAR30856.1 - 1.6e-16 60.2 0.0 4.7e-16 58.7 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 CAR30856.1 - 3.1e-16 59.6 0.0 8.8e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 CAR30856.1 - 5.7e-12 45.8 0.0 1.4e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CAR30856.1 - 1.3e-10 41.0 0.1 1.4e-09 37.7 0.0 2.5 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda Cdd1 PF11731.8 CAR30856.1 - 0.024 14.8 0.0 0.38 11.0 0.0 2.5 2 0 0 2 2 2 0 Pathogenicity locus PGK PF00162.19 CAR30857.1 - 4.2e-146 486.7 0.0 4.7e-146 486.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.11 CAR30857.1 - 0.077 12.6 0.2 0.78 9.3 0.1 2.3 2 0 0 2 2 2 0 Propionate catabolism activator ABC2_membrane PF01061.24 CAR30858.1 - 1.3e-38 132.5 17.7 1.3e-38 132.5 17.7 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CAR30858.1 - 9.5e-29 100.7 0.0 2.1e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CAR30858.1 - 0.00038 20.4 0.4 0.21 11.4 0.3 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CAR30858.1 - 0.0011 19.0 0.2 0.002 18.1 0.2 1.3 1 0 0 1 1 1 1 RsgA GTPase EGF_2 PF07974.13 CAR30858.1 - 0.0048 17.2 6.7 0.0048 17.2 6.7 3.7 4 0 0 4 4 3 2 EGF-like domain AAA_29 PF13555.6 CAR30858.1 - 0.007 16.1 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CAR30858.1 - 0.083 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TMEMspv1-c74-12 PF11044.8 CAR30858.1 - 0.12 12.4 0.7 0.43 10.6 0.7 1.9 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein NACHT PF05729.12 CAR30858.1 - 0.14 12.0 1.1 0.27 11.2 1.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 CAR30858.1 - 0.27 11.5 0.3 0.45 10.7 0.3 1.3 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.24 CAR30858.1 - 0.54 10.4 33.5 0.038 14.1 6.6 4.1 3 1 0 3 3 2 0 Laminin EGF domain RNA_pol_Rpc34 PF05158.12 CAR30859.1 - 5.7e-107 358.0 0.7 7.2e-107 357.7 0.7 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 CAR30859.1 - 0.01 15.9 1.9 0.63 10.2 0.2 2.5 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC Rrf2 PF02082.20 CAR30859.1 - 0.053 13.9 0.5 0.11 12.9 0.1 1.8 2 0 0 2 2 2 0 Transcriptional regulator Pecanex_C PF05041.15 CAR30860.1 - 0.029 13.9 0.2 0.039 13.5 0.2 1.2 1 0 0 1 1 1 0 Pecanex protein (C-terminus) Gpr1_Fun34_YaaH PF01184.19 CAR30861.1 - 1e-89 299.6 17.7 1.2e-89 299.4 17.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Gpr1_Fun34_YaaH PF01184.19 CAR30862.1 - 1.7e-91 305.4 13.5 2.1e-91 305.2 13.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BAR PF03114.18 CAR30863.1 - 1.9e-54 184.9 2.7 2.2e-54 184.6 2.7 1.1 1 0 0 1 1 1 1 BAR domain Sterol-sensing PF12349.8 CAR30864.1 - 0.00022 21.1 5.1 0.00065 19.6 0.7 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Pkinase PF00069.25 CAR30865.1 - 9.3e-47 159.6 0.1 2.8e-46 158.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30865.1 - 1.4e-24 86.8 0.0 2.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CAR30865.1 - 0.00019 21.4 0.0 0.00043 20.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CAR30865.1 - 0.00047 19.8 0.1 0.0013 18.4 0.1 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 CAR30865.1 - 0.00063 19.2 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CAR30865.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CAR30865.1 - 0.029 14.0 0.0 0.092 12.3 0.0 1.8 2 0 0 2 2 2 0 RIO1 family TFIIA PF03153.13 CAR30865.1 - 2.3 8.1 16.0 3.6 7.5 16.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Citrate_synt PF00285.21 CAR30866.1 - 2.3e-100 336.2 0.0 2.9e-100 335.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain FMN_red PF03358.15 CAR30867.1 - 1.3e-09 38.0 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 CAR30867.1 - 1.2e-06 28.7 0.0 2.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 CAR30867.1 - 5.2e-05 23.1 0.0 8.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Lge1 PF11488.8 CAR30868.1 - 0.00062 19.9 6.6 0.0011 19.1 0.6 2.2 2 0 0 2 2 2 1 Transcriptional regulatory protein LGE1 MLD PF11647.8 CAR30868.1 - 0.01 16.1 0.7 0.027 14.7 0.1 1.9 2 0 0 2 2 2 0 Membrane Localization Domain Exog_C PF18026.1 CAR30868.1 - 0.11 12.5 2.3 0.13 12.4 0.1 2.2 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain OmpH PF03938.14 CAR30868.1 - 7.7 6.9 12.3 9e+02 0.2 12.3 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_L32p PF01783.23 CAR30869.1 - 8.3e-11 42.0 8.7 8.3e-11 42.0 8.7 1.7 2 0 0 2 2 2 1 Ribosomal L32p protein family HU-CCDC81_bac_1 PF18174.1 CAR30869.1 - 0.1 12.5 0.0 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 1 Septin PF00735.18 CAR30870.1 - 4.7e-107 357.5 0.9 5.5e-107 357.2 0.9 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CAR30870.1 - 2.7e-09 37.1 0.4 5.6e-09 36.1 0.3 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR30870.1 - 2.2e-07 30.6 1.0 6.3e-05 22.6 0.3 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CAR30870.1 - 5.1e-07 29.2 0.4 1e-06 28.2 0.3 1.5 1 1 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 CAR30870.1 - 9.7e-07 28.8 1.6 3.4e-06 27.1 0.4 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CAR30870.1 - 0.0001 22.4 0.9 0.12 12.4 0.4 2.5 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 CAR30870.1 - 0.00033 21.1 0.1 0.00068 20.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 CAR30870.1 - 0.00096 18.4 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 CAR30870.1 - 0.0013 19.0 0.2 0.0043 17.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CAR30870.1 - 0.0021 18.6 0.7 0.0045 17.5 0.7 1.7 1 1 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.18 CAR30870.1 - 0.0047 16.3 0.1 0.009 15.4 0.1 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.13 CAR30870.1 - 0.0089 15.1 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_14 PF13173.6 CAR30870.1 - 0.011 15.7 0.1 0.033 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CAR30870.1 - 0.017 15.3 0.3 0.088 13.0 0.7 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CAR30870.1 - 0.019 14.7 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 CAR30870.1 - 0.021 15.0 0.1 0.051 13.8 0.1 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 CAR30870.1 - 0.022 14.3 0.1 0.049 13.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CAR30870.1 - 0.029 13.8 0.0 0.063 12.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.12 CAR30870.1 - 0.034 13.5 1.7 0.48 9.7 1.7 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MeaB PF03308.16 CAR30870.1 - 0.044 12.8 0.2 0.33 9.9 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 CAR30870.1 - 0.045 13.3 0.8 2.9 7.4 0.1 2.4 1 1 0 2 2 2 0 Ferrous iron transport protein B AAA_24 PF13479.6 CAR30870.1 - 0.06 13.1 0.7 0.24 11.1 0.1 2.1 2 1 0 2 2 2 0 AAA domain Complex1_LYR PF05347.15 CAR30870.1 - 0.14 12.2 2.0 0.18 11.9 0.2 2.0 2 0 0 2 2 2 0 Complex 1 protein (LYR family) eRF1_2 PF03464.15 CAR30871.1 - 1.7e-29 102.8 0.6 3.6e-29 101.8 0.6 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CAR30871.1 - 1.3e-23 83.7 0.0 3.1e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CAR30871.1 - 1.1e-20 74.0 1.0 1.8e-20 73.2 1.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family5 PF18846.1 CAR30871.1 - 0.67 10.2 6.9 0.12 12.6 0.7 2.5 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 5 Rer1 PF03248.13 CAR30872.1 - 3.4e-68 228.7 7.2 3.9e-68 228.5 7.2 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 CAR30872.1 - 0.0044 16.7 1.0 0.0044 16.7 1.0 1.8 2 1 0 2 2 2 1 Predicted membrane protein (DUF2208) PQ-loop PF04193.14 CAR30873.1 - 1.1e-05 25.1 16.9 0.0004 20.1 2.8 3.7 3 1 0 3 3 3 2 PQ loop repeat PLDc_2 PF13091.6 CAR30874.1 - 9.4e-15 54.7 0.0 2.9e-06 27.2 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CAR30874.1 - 2.7e-11 43.1 0.2 5e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF3481 PF11980.8 CAR30875.1 - 0.025 14.3 0.4 0.05 13.3 0.4 1.5 1 0 0 1 1 1 0 C-terminal domain of neuropilin glycoprotein UEV PF05743.13 CAR30876.1 - 1.1e-25 89.9 0.0 1.8e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 CAR30876.1 - 1.7e-23 82.3 0.2 4.2e-23 81.1 0.2 1.7 1 0 0 1 1 1 1 Vps23 core domain NPP PF08384.10 CAR30876.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Pro-opiomelanocortin, N-terminal region DKCLD PF08068.12 CAR30877.1 - 2.2e-30 104.5 0.1 2.2e-29 101.3 0.2 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CAR30877.1 - 1.6e-22 79.4 0.4 3.3e-22 78.4 0.4 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 CAR30877.1 - 2.2e-20 72.4 1.3 4.2e-20 71.5 1.3 1.5 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 CAR30877.1 - 3.7e-19 69.6 0.0 3.7e-19 69.6 0.0 4.0 2 2 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 CAR30877.1 - 0.038 14.2 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain Merozoite_SPAM PF07133.11 CAR30877.1 - 0.51 10.3 53.7 0.75 9.8 53.7 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) GAGA_bind PF06217.12 CAR30877.1 - 0.73 10.1 22.7 1.1 9.5 22.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF3807 PF12720.7 CAR30877.1 - 0.91 9.8 34.6 1.5 9.1 34.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DnaJ_C PF01556.18 CAR30878.1 - 1.2e-34 119.5 0.0 1.5e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CAR30878.1 - 1.2e-22 79.8 0.8 1.9e-22 79.1 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 CAR30879.1 - 8.6e-42 140.3 15.6 8e-11 42.3 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30879.1 - 6.4e-14 52.0 1.6 0.021 15.1 0.0 5.1 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CAR30879.1 - 1.5e-10 40.4 9.5 0.01 14.5 0.1 5.0 1 1 3 5 5 5 5 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CAR30879.1 - 5.5e-08 32.1 0.9 0.069 12.1 0.1 4.6 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 CAR30879.1 - 2.2e-05 23.4 0.7 0.45 9.2 0.0 3.7 1 1 1 3 3 3 2 Nup133 N terminal like Hira PF07569.11 CAR30879.1 - 2.3e-05 24.2 0.3 0.65 9.7 0.0 4.6 3 1 3 6 6 6 1 TUP1-like enhancer of split Frtz PF11768.8 CAR30879.1 - 0.00029 19.3 0.0 0.0014 17.0 0.0 2.0 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 CAR30879.1 - 0.0018 16.9 0.0 0.096 11.2 0.0 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 CAR30879.1 - 0.0026 16.8 2.1 0.012 14.5 0.0 2.8 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain HPS3_N PF14761.6 CAR30879.1 - 0.16 11.5 0.0 2.3 7.7 0.0 2.5 3 1 0 3 3 3 0 Hermansky-Pudlak syndrome 3 RFX_DNA_binding PF02257.15 CAR30880.1 - 3e-30 104.7 0.0 3e-30 104.7 0.0 3.2 3 0 0 3 3 3 1 RFX DNA-binding domain Pox_D5 PF03288.16 CAR30880.1 - 0.01 16.3 0.0 0.06 13.8 0.0 2.3 2 0 0 2 2 2 0 Poxvirus D5 protein-like Cdc6_C PF09079.11 CAR30880.1 - 0.1 12.6 0.0 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain Ribosomal_L30 PF00327.20 CAR30881.1 - 2.2e-12 46.6 0.9 5.2e-12 45.5 0.9 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e GAS PF13851.6 CAR30882.1 - 0.0013 18.1 70.4 0.0022 17.4 16.9 4.9 1 1 3 4 4 4 3 Growth-arrest specific micro-tubule binding CENP-H PF05837.12 CAR30882.1 - 0.0088 16.4 3.4 0.0088 16.4 3.4 6.4 1 1 4 6 6 6 1 Centromere protein H (CENP-H) KASH_CCD PF14662.6 CAR30882.1 - 0.009 15.9 27.1 0.009 15.9 27.1 5.2 1 1 4 5 5 5 1 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 CAR30882.1 - 0.0092 16.0 11.1 0.0092 16.0 11.1 4.9 1 1 3 4 4 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 CAR30882.1 - 0.026 14.8 1.2 0.026 14.8 1.2 6.4 3 2 4 7 7 7 0 TSC-22/dip/bun family HALZ PF02183.18 CAR30882.1 - 0.046 14.0 1.1 0.046 14.0 1.1 9.8 8 3 3 11 11 11 0 Homeobox associated leucine zipper DASH_Dam1 PF08653.10 CAR30882.1 - 0.89 9.4 9.8 3.2 7.6 0.1 5.2 4 1 1 5 5 5 0 DASH complex subunit Dam1 DivIC PF04977.15 CAR30882.1 - 0.94 9.3 0.0 0.46 10.3 2.7 8.6 5 2 3 9 9 9 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 CAR30882.1 - 1.8 8.8 66.0 0.36 11.0 12.6 4.5 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 SHE3 PF17078.5 CAR30882.1 - 3.8 7.2 64.6 0.016 14.9 28.9 3.8 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.21 CAR30882.1 - 3.8 7.7 40.0 0.94 9.6 0.3 7.5 4 2 5 9 9 8 0 bZIP transcription factor DUF3287 PF11690.8 CAR30882.1 - 6.4 6.5 19.0 0.31 10.8 0.2 4.6 3 2 1 5 5 5 0 Protein of unknown function (DUF3287) GSIII_N PF12437.8 CAR30883.1 - 0.28 10.8 2.6 2.4 7.8 0.3 2.2 1 1 1 2 2 2 0 Glutamine synthetase type III N terminal Iso_dh PF00180.20 CAR30885.1 - 7.1e-126 420.0 0.0 8.1e-126 419.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aminotran_5 PF00266.19 CAR30886.1 - 2.3e-97 326.3 0.0 3.1e-97 325.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CAR30886.1 - 5.5e-08 32.4 0.0 7.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CAR30886.1 - 7.6e-08 32.1 0.1 3.1e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CAR30886.1 - 4.8e-05 22.2 0.0 8.2e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 CAR30886.1 - 0.01 14.4 0.2 0.016 13.8 0.2 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Mito_carr PF00153.27 CAR30887.1 - 2.9e-51 171.3 3.8 2.7e-20 72.1 0.0 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 CAR30887.1 - 0.013 14.7 0.5 0.044 12.9 0.5 1.9 1 1 0 1 1 1 0 Gammaproteobacterial serine protease Dcc1 PF09724.9 CAR30888.1 - 9.8e-82 274.9 0.0 1.1e-81 274.7 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DUF3507 PF12015.8 CAR30889.1 - 9.6e-54 181.8 0.0 2e-53 180.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF2015 PF09435.10 CAR30890.1 - 4.7e-31 106.9 0.0 5.2e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) RRM_1 PF00076.22 CAR30891.1 - 8.2e-57 188.9 0.1 2.7e-19 68.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CAR30891.1 - 6.7e-05 22.5 0.0 1.6 8.4 0.0 3.1 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CAR30891.1 - 0.066 13.0 0.0 54 3.5 0.0 3.0 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CAR30891.1 - 0.1 12.7 0.0 24 5.1 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 CAR30891.1 - 0.14 12.0 0.0 0.66 9.9 0.0 2.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif DUF1325 PF07039.11 CAR30892.1 - 5e-39 133.4 0.0 8e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 CAR30892.1 - 7.3e-06 25.7 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 CAR30892.1 - 9.7e-05 22.8 0.1 0.04 14.4 0.0 2.6 2 0 0 2 2 2 2 Agenet domain PilZ PF07238.14 CAR30892.1 - 0.01 16.1 0.0 0.26 11.6 0.0 2.4 1 1 0 1 1 1 0 PilZ domain DUF4537 PF15057.6 CAR30892.1 - 0.021 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Mucin PF01456.17 CAR30892.1 - 0.8 9.7 9.7 1.5 8.8 9.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribosomal_L27_C PF18471.1 CAR30893.1 - 7.8e-96 320.1 15.4 9.4e-96 319.9 15.4 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Ribosomal_L27 PF01016.19 CAR30893.1 - 3.4e-31 107.1 0.4 5.7e-31 106.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein ABC_membrane_3 PF13748.6 CAR30893.1 - 0.0058 15.9 0.0 0.0095 15.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region CemA PF03040.14 CAR30893.1 - 0.88 9.5 5.1 0.51 10.2 2.8 1.7 1 1 1 2 2 2 0 CemA family UPF0449 PF15136.6 CAR30893.1 - 1.3 9.5 5.7 7.7 7.1 0.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 ALS_ss_C PF10369.9 CAR30894.1 - 5.9e-16 58.5 0.0 3.1e-15 56.1 0.0 2.2 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 CAR30894.1 - 1.1e-13 50.7 0.1 2.6e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 CAR30894.1 - 2.8e-08 33.5 0.2 1.1e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 ACT domain Limkain-b1 PF11608.8 CAR30894.1 - 0.00089 19.3 0.0 0.0054 16.8 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 Iso_dh PF00180.20 CAR30895.1 - 1.1e-71 241.8 0.0 1.3e-71 241.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HAD PF12710.7 CAR30896.1 - 4.7e-23 82.6 0.0 6.4e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 CAR30896.1 - 1.5e-07 31.0 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 CAR30896.1 - 0.0042 16.6 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 CAR30896.1 - 0.0069 16.7 0.0 0.4 10.9 0.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase UPF0052 PF01933.18 CAR30897.1 - 2.1e-61 207.7 0.0 2.6e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 EF-hand_7 PF13499.6 CAR30898.1 - 8.7e-07 29.3 0.6 8.7e-07 29.3 0.6 2.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CAR30898.1 - 2.3e-06 27.1 1.3 0.066 13.2 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CAR30898.1 - 0.00073 18.9 1.1 0.016 14.8 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 CAR30898.1 - 0.017 14.9 3.3 1.2 9.1 0.2 2.6 3 0 0 3 3 3 0 EF-hand domain pair Flavodoxin_1 PF00258.25 CAR30898.1 - 0.13 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin PLA2_B PF01735.18 CAR30899.1 - 2.7e-83 280.1 15.0 1.6e-66 224.7 7.5 3.4 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.22 CAR30899.1 - 4.2e-05 23.8 0.0 0.0001 22.6 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase ABC_tran PF00005.27 CAR30900.1 - 1.9e-44 151.5 0.2 6.9e-22 78.4 0.0 4.7 3 2 0 3 3 3 2 ABC transporter 4HB PF17947.1 CAR30900.1 - 6.3e-29 99.9 0.0 3.9e-28 97.3 0.0 2.4 2 0 0 2 2 2 1 Four helical bundle domain AAA_21 PF13304.6 CAR30900.1 - 1e-17 64.9 0.0 0.0014 18.5 0.0 5.0 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR30900.1 - 4.6e-17 62.2 0.0 6.1e-07 29.1 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CAR30900.1 - 8.7e-11 42.7 2.7 0.00038 21.0 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CAR30900.1 - 3.4e-09 36.3 0.0 0.0041 16.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAR30900.1 - 3.4e-08 33.6 0.1 0.00021 21.2 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CAR30900.1 - 2.9e-07 30.6 0.1 0.0016 18.5 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 CAR30900.1 - 3.2e-07 30.7 0.0 0.005 17.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 CAR30900.1 - 9.3e-07 29.1 0.0 5.1e-05 23.4 0.0 2.9 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 CAR30900.1 - 9.5e-07 29.2 0.0 0.055 13.7 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 CAR30900.1 - 3.6e-06 27.4 0.1 0.58 10.6 0.0 4.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CAR30900.1 - 1.2e-05 25.8 0.1 0.41 11.2 0.0 3.5 3 1 1 4 4 2 2 AAA domain RNA_helicase PF00910.22 CAR30900.1 - 1.4e-05 25.4 0.0 0.24 11.8 0.0 3.0 2 0 0 2 2 2 2 RNA helicase CLASP_N PF12348.8 CAR30900.1 - 1.6e-05 24.6 0.5 9.1e-05 22.1 0.5 2.0 1 1 0 1 1 1 1 CLASP N terminal AAA_33 PF13671.6 CAR30900.1 - 2.5e-05 24.5 0.0 0.41 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CAR30900.1 - 4.3e-05 24.0 0.2 0.23 11.8 0.0 3.3 4 0 0 4 4 3 1 AAA ATPase domain MeaB PF03308.16 CAR30900.1 - 0.00024 20.2 2.0 0.2 10.6 0.0 2.7 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ParcG PF10274.9 CAR30900.1 - 0.00025 21.2 0.3 1.5 8.9 0.0 3.2 2 1 1 3 3 3 1 Parkin co-regulated protein AAA_15 PF13175.6 CAR30900.1 - 0.00028 20.7 5.0 0.38 10.4 0.0 3.7 5 0 0 5 5 3 2 AAA ATPase domain UME PF08064.13 CAR30900.1 - 0.00036 20.4 1.9 0.14 12.1 1.2 2.7 1 1 1 2 2 2 2 UME (NUC010) domain HEAT_EZ PF13513.6 CAR30900.1 - 0.00089 19.7 6.6 0.56 10.8 0.0 3.7 5 0 0 5 5 2 2 HEAT-like repeat HEAT_2 PF13646.6 CAR30900.1 - 0.0009 19.6 1.1 0.3 11.5 0.0 3.0 1 1 1 2 2 2 2 HEAT repeats Rad17 PF03215.15 CAR30900.1 - 0.00095 19.1 0.0 0.29 11.1 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain NACHT PF05729.12 CAR30900.1 - 0.0011 18.9 0.3 0.36 10.7 0.0 2.7 3 0 0 3 3 2 1 NACHT domain DUF87 PF01935.17 CAR30900.1 - 0.0012 19.0 5.5 0.37 10.9 0.0 4.1 4 0 0 4 4 3 1 Helicase HerA, central domain MMS19_C PF12460.8 CAR30900.1 - 0.0012 18.0 4.0 0.012 14.8 0.4 2.8 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal AAA_24 PF13479.6 CAR30900.1 - 0.0014 18.4 0.2 1.4 8.6 0.0 3.3 4 0 0 4 4 3 1 AAA domain DUF445 PF04286.12 CAR30900.1 - 0.0014 18.5 0.6 0.003 17.4 0.2 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF445) AAA_27 PF13514.6 CAR30900.1 - 0.0016 18.1 0.0 1.6 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAR30900.1 - 0.0019 17.9 0.1 3.6 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain CLP1_P PF16575.5 CAR30900.1 - 0.0027 17.5 0.2 0.44 10.3 0.0 3.2 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop G-alpha PF00503.20 CAR30900.1 - 0.0035 16.5 0.0 1.3 8.1 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit AAA_14 PF13173.6 CAR30900.1 - 0.0038 17.3 0.0 6.5 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 CAR30900.1 - 0.0043 16.8 0.0 0.27 11.0 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 CAR30900.1 - 0.0045 16.9 0.1 3.6 7.4 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Adaptin_N PF01602.20 CAR30900.1 - 0.0049 15.5 4.0 0.0071 15.0 2.8 1.7 1 1 1 2 2 2 1 Adaptin N terminal region SbcCD_C PF13558.6 CAR30900.1 - 0.0052 17.0 0.0 0.75 10.1 0.0 3.5 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit cobW PF02492.19 CAR30900.1 - 0.0085 15.7 0.5 4.3 6.9 0.0 3.2 4 0 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin PF02224.18 CAR30900.1 - 0.0098 15.6 0.0 6 6.5 0.1 2.5 2 0 0 2 2 2 0 Cytidylate kinase Roc PF08477.13 CAR30900.1 - 0.011 16.0 0.0 6.8 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 CAR30900.1 - 0.012 16.1 1.0 2.5 8.5 0.2 3.4 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CAR30900.1 - 0.017 14.6 0.0 7.4 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 CAR30900.1 - 0.02 14.7 0.3 7.6 6.2 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 CAR30900.1 - 0.024 13.7 0.1 1.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 CAR30900.1 - 0.029 13.8 0.0 1.6 8.0 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 CAR30900.1 - 0.04 13.8 0.0 14 5.5 0.1 2.8 2 0 0 2 2 2 0 NTPase Ploopntkinase3 PF18751.1 CAR30900.1 - 0.047 13.6 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Septin PF00735.18 CAR30900.1 - 0.05 12.9 0.4 2.4 7.4 0.0 2.8 3 0 0 3 3 3 0 Septin NUC173 PF08161.12 CAR30900.1 - 0.089 12.4 1.8 1.7 8.3 1.8 2.2 1 1 1 2 2 2 0 NUC173 domain AAA_5 PF07728.14 CAR30900.1 - 0.09 12.8 0.0 28 4.7 0.0 3.5 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) MutS_V PF00488.21 CAR30900.1 - 0.093 12.7 0.1 7.4 6.5 0.1 2.6 2 0 0 2 2 2 0 MutS domain V IstB_IS21 PF01695.17 CAR30900.1 - 0.097 12.4 0.0 16 5.1 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein FeoB_N PF02421.18 CAR30900.1 - 0.18 11.3 0.4 1.2 8.7 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_13 PF13166.6 CAR30900.1 - 0.18 10.4 9.2 2.5 6.6 0.0 4.3 5 0 0 5 5 5 0 AAA domain Ac76 PF05814.11 CAR30900.1 - 2.3 8.3 4.5 96 3.1 0.0 3.1 3 0 0 3 3 3 0 Orf76 (Ac76) Pkinase PF00069.25 CAR30901.1 - 4.4e-56 190.2 0.0 1e-55 188.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30901.1 - 2.4e-23 82.7 0.0 7.6e-23 81.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR30901.1 - 8.8e-07 28.5 0.1 0.037 13.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CAR30901.1 - 0.0006 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CAR30901.1 - 0.012 14.4 0.1 0.14 10.9 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase SNF2_N PF00176.23 CAR30902.1 - 6.6e-46 156.6 0.3 1.5e-45 155.5 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 CAR30902.1 - 2.3e-10 40.2 9.8 2.3e-10 40.2 9.8 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR30902.1 - 1.9e-09 37.2 11.0 6.4e-09 35.5 11.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR30902.1 - 2.6e-09 37.3 11.0 2.6e-09 37.3 11.0 2.4 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CAR30902.1 - 1e-08 34.9 7.4 3.2e-08 33.3 7.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR30902.1 - 7.9e-07 28.8 8.9 2e-06 27.6 8.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CAR30902.1 - 4.1e-06 27.0 9.9 2.1e-05 24.7 9.0 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CAR30902.1 - 1.4e-05 25.0 8.3 5.9e-05 23.0 8.3 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CAR30902.1 - 4.1e-05 23.6 8.7 0.00011 22.2 8.7 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CAR30902.1 - 0.00016 21.6 10.8 0.00061 19.7 10.8 2.1 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.31 CAR30902.1 - 0.00057 20.2 0.2 0.0044 17.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_10 PF16685.5 CAR30902.1 - 0.0093 16.1 3.6 0.07 13.3 4.1 2.2 2 0 0 2 2 1 1 zinc RING finger of MSL2 Nucleoporin_FG2 PF15967.5 CAR30902.1 - 0.013 14.0 1.6 0.022 13.3 1.6 1.2 1 0 0 1 1 1 0 Nucleoporin FG repeated region zf-UDP PF14569.6 CAR30902.1 - 0.014 15.5 1.7 0.048 13.8 1.7 2.0 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-P11 PF03854.14 CAR30902.1 - 0.015 15.0 7.1 0.058 13.1 7.1 2.0 1 0 0 1 1 1 0 P-11 zinc finger ResIII PF04851.15 CAR30902.1 - 0.017 15.1 0.0 0.017 15.1 0.0 2.6 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit zf-RING_4 PF14570.6 CAR30902.1 - 0.26 11.1 7.6 0.77 9.6 7.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 CAR30902.1 - 0.37 10.9 6.0 0.24 11.5 3.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 CAR30902.1 - 0.53 10.2 2.9 1.7 8.6 2.9 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 CAR30902.1 - 1.1 9.1 8.9 4.3 7.2 8.9 2.2 1 0 0 1 1 1 0 RING-like zinc finger Jak1_Phl PF17887.1 CAR30902.1 - 1.9 8.5 4.8 0.59 10.1 0.9 2.1 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain zf-Nse PF11789.8 CAR30902.1 - 2.6 7.9 5.6 8.4 6.3 5.6 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit HsdM_N PF12161.8 CAR30903.1 - 0.097 13.3 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 HsdM N-terminal domain Clat_adaptor_s PF01217.20 CAR30904.1 - 7.4e-55 184.8 0.0 8.5e-55 184.6 0.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 CAR30904.1 - 0.089 13.5 0.0 0.21 12.3 0.0 1.6 2 0 0 2 2 2 0 Pullulanase N1-terminal domain TP_methylase PF00590.20 CAR30905.1 - 1.1e-26 94.1 0.0 1.6e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.6 CAR30905.1 - 0.052 13.5 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) Pec_lyase_C PF00544.19 CAR30906.1 - 0.00019 21.1 0.7 0.0048 16.5 0.1 2.4 2 0 0 2 2 2 1 Pectate lyase AlphaC_N PF08829.10 CAR30906.1 - 0.064 13.3 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Alpha C protein N terminal ABC1 PF03109.16 CAR30908.1 - 4.2e-32 110.8 0.0 8.2e-32 109.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CAR30908.1 - 0.0017 18.0 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 RIO1 family TPR_MLP1_2 PF07926.12 CAR30909.1 - 0.001 19.1 4.3 0.001 19.1 4.3 2.4 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 CAR30909.1 - 0.0022 18.0 10.4 0.0024 18.0 0.6 2.9 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CAR30909.1 - 0.0063 16.6 0.5 0.0063 16.6 0.5 3.7 3 2 1 4 4 4 1 Basic region leucine zipper Phlebovirus_NSM PF07246.11 CAR30909.1 - 0.0083 15.5 1.7 0.0083 15.5 1.7 1.4 1 1 0 1 1 1 1 Phlebovirus nonstructural protein NS-M DUF5401 PF17380.2 CAR30909.1 - 0.013 13.7 10.9 0.016 13.3 10.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) JIP_LZII PF16471.5 CAR30909.1 - 0.038 14.1 1.9 0.038 14.1 1.9 3.1 2 1 2 4 4 4 0 JNK-interacting protein leucine zipper II Scaffolding_pro PF11418.8 CAR30909.1 - 0.053 14.1 3.1 0.058 14.0 0.8 2.1 1 1 0 2 2 2 0 Phi29 scaffolding protein FUSC PF04632.12 CAR30909.1 - 0.074 11.6 0.5 0.081 11.5 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.7 CAR30909.1 - 0.083 13.0 15.4 0.4 10.8 15.4 1.9 1 1 0 1 1 1 0 Tropomyosin like MbeD_MobD PF04899.12 CAR30909.1 - 0.2 11.8 3.9 0.12 12.5 0.7 2.4 2 1 1 3 3 3 0 MbeD/MobD like Spc7 PF08317.11 CAR30909.1 - 0.22 10.3 14.7 0.54 9.1 6.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TSC22 PF01166.18 CAR30909.1 - 0.29 11.5 9.4 0.24 11.8 1.9 3.2 1 1 1 2 2 2 0 TSC-22/dip/bun family FlaC_arch PF05377.11 CAR30909.1 - 0.53 10.7 8.0 4.7 7.7 0.6 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 CAR30909.1 - 0.66 10.0 10.7 2.3 8.3 0.5 3.1 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding ZapB PF06005.12 CAR30909.1 - 1.3 9.5 14.3 2.4 8.6 7.2 2.8 1 1 1 2 2 2 0 Cell division protein ZapB DUF1664 PF07889.12 CAR30909.1 - 1.7 8.7 5.8 3.5 7.7 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SlyX PF04102.12 CAR30909.1 - 2.6 8.7 8.5 1.8 9.2 1.7 2.7 1 1 1 2 2 2 0 SlyX ACCA PF03255.14 CAR30909.1 - 3.3 7.6 7.2 0.77 9.6 1.4 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit YabA PF06156.13 CAR30909.1 - 3.4 8.4 12.1 2.7 8.7 5.0 2.3 1 1 1 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 CAR30909.1 - 3.8 8.0 16.6 24 5.5 16.6 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region Cnn_1N PF07989.11 CAR30909.1 - 4.1 7.6 16.8 3 8.1 9.6 2.7 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 V_ATPase_I PF01496.19 CAR30909.1 - 4.9 4.9 7.9 5.4 4.8 7.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DMPK_coil PF08826.10 CAR30909.1 - 8.4 6.6 11.5 0.35 11.0 0.7 3.1 2 1 1 3 3 3 0 DMPK coiled coil domain like OCD_Mu_crystall PF02423.15 CAR30910.1 - 1.9e-08 33.6 0.0 5e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Zn_clus PF00172.18 CAR30911.1 - 1.2e-07 31.7 9.1 2.6e-07 30.6 9.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CAR30911.1 - 7.3e-07 28.5 0.4 2.3e-05 23.6 0.1 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain G_glu_transpept PF01019.21 CAR30912.1 - 4.9e-121 405.0 0.0 5.8e-121 404.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Ferric_reduct PF01794.19 CAR30913.1 - 3.9e-25 88.4 8.3 3.9e-25 88.4 8.3 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CAR30913.1 - 7.3e-12 45.7 0.0 1.1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CAR30913.1 - 5.1e-10 39.4 0.2 1.2e-09 38.2 0.2 1.5 1 0 0 1 1 1 1 FAD-binding domain baeRF_family3 PF18845.1 CAR30914.1 - 0.044 14.0 1.4 0.62 10.3 0.3 2.9 2 1 1 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 3 baeRF_family7 PF18849.1 CAR30914.1 - 0.076 13.2 0.9 0.2 11.9 0.9 1.7 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 7 SH3BGR PF04908.15 CAR30915.1 - 0.066 13.4 0.0 0.066 13.4 0.0 4.3 4 1 1 5 5 5 0 SH3-binding, glutamic acid-rich protein HTH_AraC PF00165.23 CAR30916.1 - 0.0098 16.0 0.0 0.039 14.1 0.0 2.0 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family Glycogen_syn PF05693.13 CAR30917.1 - 0 1109.6 0.0 0 1109.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CAR30917.1 - 2.7e-09 36.8 0.0 2.9e-06 26.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CAR30917.1 - 5.4e-07 30.1 0.0 0.0021 18.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CAR30917.1 - 6.5e-05 23.0 0.8 0.00013 22.0 0.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 CAR30917.1 - 0.00018 21.3 0.3 0.00042 20.1 0.3 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 CAR30917.1 - 0.0003 21.3 0.1 0.00074 20.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Pkinase PF00069.25 CAR30918.1 - 4.3e-70 236.1 0.0 6e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30918.1 - 2e-40 138.7 0.0 4.4e-40 137.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR30918.1 - 1.5e-05 24.4 0.1 0.00029 20.2 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CAR30918.1 - 0.0018 17.1 1.2 0.0072 15.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CAR30918.1 - 0.009 15.4 0.0 0.042 13.2 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family WHIM1 PF15612.6 CAR30919.1 - 2.2e-07 30.3 0.0 5e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF349 PF03993.12 CAR30919.1 - 0.0066 16.7 1.7 0.0066 16.7 1.7 3.1 2 0 0 2 2 2 1 Domain of Unknown Function (DUF349) DDHD PF02862.17 CAR30919.1 - 5 7.2 7.4 20 5.2 1.5 2.6 2 0 0 2 2 2 0 DDHD domain zf-rbx1 PF12678.7 CAR30920.1 - 3.6e-09 36.8 5.8 6.8e-09 35.9 5.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CAR30920.1 - 3.3e-08 33.7 8.1 1.1e-07 32.1 8.1 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CAR30920.1 - 5.8e-07 29.4 4.0 1e-06 28.6 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CAR30920.1 - 1.5e-06 27.9 2.7 1.5e-06 27.9 2.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CAR30920.1 - 1.8e-05 24.4 6.3 0.00063 19.4 0.9 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-C3HC4 PF00097.25 CAR30920.1 - 2.1e-05 24.3 6.4 4.1e-05 23.4 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR30920.1 - 5.5e-05 23.1 1.3 5.5e-05 23.1 1.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CAR30920.1 - 6.3e-05 22.7 4.6 0.00012 21.8 4.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CAR30920.1 - 0.00081 19.0 2.7 0.0029 17.2 2.7 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CAR30920.1 - 0.00096 19.0 5.6 0.0031 17.3 5.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CAR30920.1 - 0.0013 18.8 1.7 0.0026 17.8 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CAR30920.1 - 0.0025 18.0 3.5 0.0074 16.4 3.5 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain DUF5589 PF17672.1 CAR30920.1 - 1.2 9.1 7.5 0.046 13.7 1.4 1.8 2 0 0 2 2 1 0 Family of unknown function (DUF5589) RINGv PF12906.7 CAR30920.1 - 1.5 9.0 5.7 4.1 7.6 5.7 1.8 1 1 0 1 1 1 0 RING-variant domain zf-P11 PF03854.14 CAR30920.1 - 2.7 7.7 5.3 0.91 9.2 1.9 1.9 2 0 0 2 2 2 0 P-11 zinc finger UDPGP PF01704.18 CAR30921.1 - 1.2e-184 613.8 0.0 1.4e-184 613.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF3137 PF11335.8 CAR30921.1 - 0.037 14.0 0.4 0.1 12.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3137) Zn_clus PF00172.18 CAR30922.1 - 1.1e-08 35.1 11.5 1.9e-08 34.3 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OTU PF02338.19 CAR30923.1 - 1.5e-28 99.8 0.1 1.5e-28 99.8 0.1 2.0 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CAR30923.1 - 2.3e-05 24.0 0.1 2.3e-05 24.0 0.1 2.4 2 1 0 2 2 2 1 Peptidase C65 Otubain DUF3447 PF11929.8 CAR30923.1 - 0.096 12.7 1.8 0.26 11.3 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) DUF4407 PF14362.6 CAR30923.1 - 4.4 6.6 8.0 6.3 6.0 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YchF-GTPase_C PF06071.13 CAR30924.1 - 2e-33 114.4 0.0 4.6e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CAR30924.1 - 9.7e-16 57.9 0.0 2.2e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CAR30924.1 - 5.8e-06 26.3 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CAR30924.1 - 0.00084 18.9 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Ribosomal_S10 PF00338.22 CAR30925.1 - 1.7e-25 89.1 0.4 2e-25 88.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF1688 PF07958.11 CAR30926.1 - 4.2e-158 526.5 0.0 4.7e-158 526.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Lung_7-TM_R PF06814.13 CAR30927.1 - 1.7e-83 280.3 25.0 2.1e-83 280.0 25.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PHO4 PF01384.20 CAR30927.1 - 0.00018 20.7 2.8 0.0031 16.6 0.0 2.1 2 0 0 2 2 2 2 Phosphate transporter family Abhydrolase_9_N PF15420.6 CAR30927.1 - 0.23 11.5 10.6 0.36 10.8 2.3 2.3 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus NifU PF01106.17 CAR30928.1 - 1.1e-25 89.6 0.0 1.8e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CAR30928.1 - 7.3e-25 86.9 0.0 1.5e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal YojJ PF10372.9 CAR30928.1 - 0.11 12.6 0.4 0.29 11.2 0.4 1.7 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus Pterin_4a PF01329.19 CAR30929.1 - 1.2e-22 79.8 0.2 1.5e-22 79.6 0.2 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Adap_comp_sub PF00928.21 CAR30930.1 - 7.2e-67 225.5 0.3 9.6e-67 225.1 0.3 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family RSB_motif PF16294.5 CAR30930.1 - 3.6 7.9 10.2 0.38 11.0 4.8 2.0 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif ADIP PF11559.8 CAR30931.1 - 0.0039 17.3 1.8 0.0083 16.2 1.8 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Opi1 PF08618.10 CAR30932.1 - 7e-27 94.7 7.3 2.5e-19 69.8 2.9 2.9 1 1 1 2 2 2 2 Transcription factor Opi1 EnY2 PF10163.9 CAR30932.1 - 0.15 12.5 8.6 0.29 11.5 4.1 3.0 3 0 0 3 3 3 0 Transcription factor e(y)2 Folliculin PF11704.8 CAR30932.1 - 9.3 6.1 11.4 4.3e+02 0.7 11.4 2.5 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Snf7 PF03357.21 CAR30933.1 - 8.6e-32 110.1 16.2 8.6e-32 110.1 16.2 1.7 1 1 1 2 2 2 1 Snf7 PAS_7 PF12860.7 CAR30933.1 - 0.0046 17.1 2.5 0.42 10.8 0.1 3.0 1 1 2 3 3 3 2 PAS fold PSD4 PF07631.11 CAR30933.1 - 0.81 10.2 7.8 0.35 11.4 0.4 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1592) CLU PF13236.6 CAR30934.1 - 2.5e-64 217.2 0.0 4.5e-64 216.3 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CAR30934.1 - 2e-34 119.1 0.0 1.3e-33 116.5 0.0 2.5 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 CAR30934.1 - 1.8e-19 69.9 0.1 1e-18 67.5 0.1 2.5 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 CAR30934.1 - 1.8e-05 24.9 1.0 0.0067 16.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CAR30934.1 - 0.029 14.2 0.1 0.61 10.0 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fib_alpha PF08702.10 CAR30934.1 - 7.5 6.7 8.8 0.99 9.6 2.6 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Mig-14 PF07395.11 CAR30935.1 - 0.17 11.3 0.1 0.25 10.7 0.1 1.2 1 0 0 1 1 1 0 Mig-14 BUD22 PF09073.10 CAR30936.1 - 5.2e-74 250.1 64.9 8.3e-74 249.5 64.9 1.4 1 1 0 1 1 1 1 BUD22 p450 PF00067.22 CAR30937.1 - 2.3e-55 188.2 0.1 3.1e-55 187.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DHNA PF04038.12 CAR30937.1 - 0.13 12.8 0.1 12 6.5 0.0 2.5 2 0 0 2 2 2 0 Dihydroneopterin aldolase Spc42p PF11544.8 CAR30938.1 - 8.3e-34 115.4 3.5 8.3e-34 115.4 3.5 2.7 3 1 0 3 3 3 1 Spindle pole body component Spc42p Csm1_N PF18504.1 CAR30938.1 - 0.39 11.1 11.7 0.11 12.9 1.9 3.2 3 0 0 3 3 3 0 Csm1 N-terminal domain KilA-N PF04383.13 CAR30939.1 - 0.0022 17.8 0.0 0.0085 15.9 0.0 1.9 1 1 0 1 1 1 1 KilA-N domain Fungal_trans PF04082.18 CAR30940.1 - 2.1e-17 63.1 12.3 2.1e-17 63.1 12.3 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CAR30940.1 - 5.5e-09 36.0 12.1 5.5e-09 36.0 12.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trypan_PARP PF05887.11 CAR30940.1 - 0.042 13.8 0.3 0.042 13.8 0.3 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) DNA_primase_lrg PF04104.14 CAR30941.1 - 8.8e-86 287.6 0.7 1.9e-85 286.5 0.1 1.8 2 0 0 2 2 2 1 Eukaryotic and archaeal DNA primase, large subunit DUF2608 PF11019.8 CAR30941.1 - 0.037 13.5 0.0 0.098 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) Amino_oxidase PF01593.24 CAR30942.1 - 1.9e-61 208.7 0.0 2.7e-61 208.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CAR30942.1 - 1.6e-12 47.4 0.3 3.3e-12 46.4 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CAR30942.1 - 6.4e-05 22.2 0.3 0.00011 21.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CAR30942.1 - 0.00034 20.3 0.1 0.0011 18.6 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CAR30942.1 - 0.0004 19.7 1.8 0.025 13.9 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CAR30942.1 - 0.00069 19.0 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CAR30942.1 - 0.0031 16.8 0.2 0.0052 16.0 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 CAR30942.1 - 0.0042 16.4 0.4 0.013 14.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CAR30942.1 - 0.0095 14.7 0.4 0.046 12.4 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein Shikimate_DH PF01488.20 CAR30942.1 - 0.013 15.6 0.2 0.023 14.7 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 CAR30942.1 - 0.027 15.0 0.3 0.058 14.0 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CAR30942.1 - 0.031 13.4 0.3 0.058 12.5 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A IlvN PF07991.12 CAR30942.1 - 0.053 13.1 0.2 0.098 12.2 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_oxidored PF12831.7 CAR30942.1 - 0.057 12.8 0.1 0.089 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CAR30942.1 - 0.18 12.3 0.1 0.59 10.6 0.0 1.9 3 0 0 3 3 2 0 Putative NAD(P)-binding FMO-like PF00743.19 CAR30942.1 - 0.18 10.2 0.1 0.27 9.6 0.1 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like AlaDh_PNT_C PF01262.21 CAR30942.1 - 0.26 10.6 0.1 0.52 9.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Copper-fist PF00649.18 CAR30943.1 - 1.3e-18 66.2 4.0 1.3e-18 66.2 4.0 2.3 3 0 0 3 3 3 1 Copper fist DNA binding domain UQ_con PF00179.26 CAR30944.1 - 5.4e-49 165.4 0.0 6.2e-49 165.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CAR30944.1 - 0.19 12.0 2.6 0.24 11.7 0.6 2.0 2 1 0 2 2 2 0 RWD domain Glyco_hydro_76 PF03663.14 CAR30945.1 - 2.3e-149 497.9 24.5 2.7e-149 497.7 24.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF2347 PF09804.9 CAR30946.1 - 3.9e-74 249.8 0.0 6e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 CAR30946.1 - 2.1e-13 50.8 4.2 1.8e-08 34.7 0.1 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF4484) Avl9 PF09794.9 CAR30946.1 - 6.2e-05 21.9 0.0 0.003 16.3 0.0 2.8 2 1 0 2 2 2 1 Transport protein Avl9 SPA PF08616.10 CAR30946.1 - 0.0098 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis BLI1 PF17324.2 CAR30947.1 - 2.4e-53 179.5 11.0 2.7e-53 179.3 11.0 1.0 1 0 0 1 1 1 1 BLOC-1 interactor 1 Synaphin PF05835.12 CAR30947.1 - 0.0083 16.4 5.7 0.011 16.0 5.7 1.2 1 0 0 1 1 1 1 Synaphin protein Hrs_helical PF12210.8 CAR30947.1 - 0.048 14.2 4.0 0.065 13.8 3.7 1.5 1 1 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate AAA_23 PF13476.6 CAR30947.1 - 1.4 9.4 7.7 1.7 9.1 7.7 1.2 1 0 0 1 1 1 0 AAA domain MnmE_helical PF12631.7 CAR30948.1 - 4.1e-43 148.0 1.9 5.2e-43 147.6 1.9 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 CAR30948.1 - 2.3e-34 118.2 0.0 5.5e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 CAR30948.1 - 1.1e-23 83.4 0.5 3.4e-23 81.9 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CAR30948.1 - 3.1e-15 56.0 0.3 6.6e-15 55.0 0.3 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CAR30948.1 - 2.8e-11 43.6 3.9 7.1e-05 22.8 0.4 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CAR30948.1 - 9.6e-09 35.1 0.1 4.1e-07 29.7 0.2 2.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 CAR30948.1 - 1.9e-07 30.8 0.0 5.2e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Ras family Arf PF00025.21 CAR30948.1 - 2.8e-07 30.1 1.3 0.0058 16.1 0.0 2.5 3 0 0 3 3 3 2 ADP-ribosylation factor family Dynamin_N PF00350.23 CAR30948.1 - 1.3e-06 28.6 4.3 0.0013 18.9 0.1 3.0 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 CAR30948.1 - 6.6e-06 25.6 0.7 2.5e-05 23.7 0.7 1.9 1 1 0 1 1 1 1 AIG1 family Roc PF08477.13 CAR30948.1 - 7.7e-05 22.9 0.0 0.0039 17.4 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CAR30948.1 - 0.002 17.9 0.1 0.28 10.9 0.1 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 CAR30948.1 - 0.0066 15.5 0.0 0.088 11.8 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 CAR30948.1 - 0.02 14.1 2.3 1.5 7.9 0.1 3.1 2 1 1 3 3 3 0 G-protein alpha subunit cobW PF02492.19 CAR30948.1 - 0.021 14.4 0.3 0.81 9.3 0.2 2.4 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 CAR30948.1 - 0.021 14.2 0.5 0.066 12.6 0.5 1.9 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CAR30948.1 - 0.028 14.9 0.5 0.078 13.5 0.5 1.9 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 CAR30948.1 - 0.047 13.0 4.7 0.25 10.7 0.2 2.7 2 2 0 2 2 2 0 Gtr1/RagA G protein conserved region ATPase_2 PF01637.18 CAR30948.1 - 0.071 13.0 1.0 0.59 10.0 1.0 2.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 CAR30948.1 - 0.071 12.9 0.2 5.5 6.7 0.1 3.3 4 1 0 4 4 3 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 CAR30948.1 - 0.072 12.8 0.1 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain COMP PF11598.8 CAR30948.1 - 3.7 8.1 7.4 2.3 8.7 2.0 3.2 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein dsrm PF00035.26 CAR30949.1 - 5.7e-08 33.4 0.0 1.3e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 CAR30949.1 - 0.0037 17.9 0.0 0.012 16.2 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease III domain Peptidase_C34 PF05413.11 CAR30950.1 - 0.084 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase Prefoldin_2 PF01920.20 CAR30950.1 - 0.086 12.8 1.0 0.19 11.7 0.3 1.8 2 0 0 2 2 2 0 Prefoldin subunit Pex2_Pex12 PF04757.14 CAR30951.1 - 6.6e-39 133.8 8.1 8.3e-39 133.5 8.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CAR30951.1 - 4.1e-06 26.5 3.3 7e-06 25.8 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR30951.1 - 0.0046 16.8 5.1 0.0073 16.1 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CAR30951.1 - 0.13 12.1 5.8 0.24 11.3 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CAR30951.1 - 0.3 11.5 4.3 0.53 10.7 4.3 1.4 1 0 0 1 1 1 0 Ring finger domain Rad50_zn_hook PF04423.14 CAR30951.1 - 1 9.3 3.6 57 3.7 0.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.6 CAR30951.1 - 1.3 9.2 5.5 2.4 8.4 5.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3797 PF12677.7 CAR30951.1 - 4.5 7.2 5.4 1 9.3 1.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) F_bP_aldolase PF01116.20 CAR30952.1 - 2.9e-88 296.0 0.0 3.3e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF89 PF01937.19 CAR30953.1 - 1.2e-117 392.8 1.4 1.4e-117 392.6 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DWNN PF08783.11 CAR30954.1 - 3.5e-32 110.5 1.6 9.4e-32 109.1 0.1 2.1 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 CAR30954.1 - 1.4e-07 31.2 5.3 1.4e-07 31.2 5.3 2.7 3 0 0 3 3 3 1 Zinc knuckle zf-Nse PF11789.8 CAR30954.1 - 0.0001 22.1 0.5 0.00027 20.7 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CCHC PF00098.23 CAR30954.1 - 0.0016 18.5 2.2 0.0016 18.5 2.2 2.2 2 0 0 2 2 2 1 Zinc knuckle U-box PF04564.15 CAR30954.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-CCHC_5 PF14787.6 CAR30954.1 - 0.015 15.0 0.5 0.039 13.7 0.5 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Zn_Tnp_IS1595 PF12760.7 CAR30954.1 - 0.057 13.4 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Rubredoxin PF00301.20 CAR30954.1 - 0.077 13.0 5.4 4.7 7.3 0.1 3.1 3 0 0 3 3 3 0 Rubredoxin zf-CCHC_3 PF13917.6 CAR30954.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-MIZ PF02891.20 CAR30954.1 - 0.31 10.8 1.8 0.91 9.3 1.8 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger TFIIA_gamma_C PF02751.14 CAR30955.1 - 8.9e-24 83.4 0.1 1.4e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 CAR30955.1 - 4.3e-22 77.9 0.1 5.6e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TAP42 PF04177.12 CAR30956.1 - 2.2e-83 280.0 19.3 2.6e-83 279.8 19.3 1.0 1 0 0 1 1 1 1 TAP42-like family Pox_A22 PF04848.13 CAR30956.1 - 0.21 11.7 2.4 0.32 11.1 0.2 2.1 2 0 0 2 2 2 0 Poxvirus A22 protein SlyX PF04102.12 CAR30956.1 - 9.1 7.0 8.1 1.7 9.3 0.7 3.3 2 1 0 3 3 3 0 SlyX Nup160 PF11715.8 CAR30957.1 - 2.2e-21 76.2 1.8 3.6e-21 75.4 1.8 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Pathogen_betaC1 PF09593.10 CAR30957.1 - 0.11 12.5 0.8 10 6.1 0.0 2.8 3 0 0 3 3 3 0 Beta-satellite pathogenicity beta C1 protein Striatin PF08232.12 CAR30958.1 - 7e-20 72.2 0.7 7e-20 72.2 0.7 3.5 2 2 1 3 3 3 1 Striatin family TCTP PF00838.17 CAR30959.1 - 4.6e-72 241.8 0.4 5.1e-72 241.6 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Nse4-Nse3_bdg PF15412.6 CAR30959.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE adh_short PF00106.25 CAR30960.1 - 3.2e-36 124.6 0.6 2e-26 92.7 0.5 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CAR30960.1 - 6.4e-26 91.3 1.9 6.9e-23 81.4 0.6 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CAR30960.1 - 0.00019 21.0 0.1 0.08 12.4 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family TrwC PF08751.11 CAR30960.1 - 0.0085 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 TrwC relaxase KR PF08659.10 CAR30960.1 - 0.012 15.5 0.6 0.23 11.4 0.5 2.5 2 1 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.15 CAR30960.1 - 0.088 11.9 0.8 0.81 8.8 0.2 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein CUE PF02845.16 CAR30961.1 - 0.0015 18.1 0.1 0.0038 16.9 0.1 1.7 1 0 0 1 1 1 1 CUE domain UPF0203 PF05254.12 CAR30962.1 - 3e-27 94.6 4.4 3.5e-27 94.5 4.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 CAR30962.1 - 5.5e-05 23.3 0.8 8.2e-05 22.7 0.8 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.10 CAR30962.1 - 0.027 14.5 2.9 0.24 11.5 1.4 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 CAR30962.1 - 0.087 13.2 1.5 0.24 11.8 1.5 1.7 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 CAR30962.1 - 0.12 12.7 3.2 7.3 7.0 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Mvb12 PF09452.10 CAR30962.1 - 1 9.8 3.5 0.47 10.9 0.8 1.8 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 Lipid_DES PF08557.10 CAR30963.1 - 6.8e-20 70.3 0.4 1.3e-19 69.4 0.4 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 CAR30963.1 - 2.4e-15 57.0 15.5 3.5e-15 56.5 14.0 1.9 1 1 1 2 2 2 2 Fatty acid desaturase DUF3464 PF11947.8 CAR30964.1 - 0.16 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SPT_ssu-like PF11779.8 CAR30965.1 - 0.1 12.3 3.0 0.13 11.9 3.0 1.2 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like Pkinase PF00069.25 CAR30966.1 - 7.6e-36 123.8 0.0 1.3e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30966.1 - 1.4e-21 77.0 0.0 2e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CAR30966.1 - 3.6e-05 23.2 0.0 0.00014 21.3 0.1 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CAR30966.1 - 0.0032 17.4 1.1 0.88 9.4 0.0 2.8 3 0 0 3 3 3 2 Phosphotransferase enzyme family ORC2 PF04084.14 CAR30967.1 - 4.7e-111 370.9 0.0 6.1e-111 370.5 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 CENP-N PF05238.13 CAR30967.1 - 0.076 12.3 5.3 0.11 11.8 5.3 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like tRNA-synt_2 PF00152.20 CAR30968.1 - 1.7e-75 254.1 0.3 2.2e-75 253.7 0.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CAR30968.1 - 5.2e-13 48.8 0.0 2.5e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CAR30968.1 - 2.7e-07 30.3 0.0 0.002 17.7 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) E1-E2_ATPase PF00122.20 CAR30969.1 - 2.6e-32 111.8 23.5 1.1e-29 103.3 0.2 3.4 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CAR30969.1 - 6.5e-29 100.9 0.7 6.5e-29 100.9 0.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CAR30969.1 - 3e-19 68.9 0.0 6.1e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CAR30969.1 - 5.2e-19 69.4 0.0 1.8e-17 64.4 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CAR30969.1 - 2.1e-10 40.1 0.0 9.7e-10 38.0 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CAR30969.1 - 0.0046 16.7 0.4 0.022 14.5 0.5 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FtsJ PF01728.19 CAR30970.1 - 7.2e-66 221.7 0.0 8.7e-66 221.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CAR30970.1 - 0.096 12.5 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S10 PF00338.22 CAR30971.1 - 6.2e-32 109.7 0.0 9.9e-32 109.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-RING_2 PF13639.6 CAR30972.1 - 4.4e-10 39.7 13.7 7.8e-10 38.9 13.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CAR30972.1 - 9.1e-08 32.3 11.1 9.1e-08 32.3 11.1 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CAR30972.1 - 1.6e-05 24.8 7.9 2.7e-05 24.1 7.9 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CAR30972.1 - 4.7e-05 23.2 13.7 9.6e-05 22.2 13.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CAR30972.1 - 0.00051 19.8 13.8 0.0022 17.8 14.1 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CAR30972.1 - 0.001 19.0 9.0 0.001 19.0 9.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger HEPN_DZIP3 PF18738.1 CAR30972.1 - 0.058 13.1 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN zf-RING_11 PF17123.5 CAR30972.1 - 0.075 12.8 9.8 0.18 11.6 9.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 CAR30972.1 - 0.098 12.5 11.2 0.36 10.7 10.9 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CAR30972.1 - 0.2 11.5 14.4 0.1 12.5 6.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CAR30972.1 - 0.61 10.1 10.6 1.1 9.3 10.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Rad50_zn_hook PF04423.14 CAR30972.1 - 1 9.2 5.6 23 4.9 0.1 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.8 CAR30972.1 - 1.3 9.3 12.8 0.9 9.8 9.0 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain zf-P11 PF03854.14 CAR30972.1 - 5.2 6.8 12.1 6.3 6.6 9.5 2.1 1 1 1 2 2 2 0 P-11 zinc finger Pkinase PF00069.25 CAR30973.1 - 2.6e-74 249.9 0.2 3.2e-74 249.6 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CAR30973.1 - 1e-44 152.8 0.0 1.3e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR30973.1 - 1.2e-06 28.1 0.0 2.3e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 CAR30973.1 - 0.0045 16.5 0.3 0.0097 15.4 0.1 1.6 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL FTA2 PF13095.6 CAR30973.1 - 0.0059 16.3 0.3 0.37 10.4 0.0 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CAR30973.1 - 0.033 13.5 0.0 0.096 12.0 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.29 CAR30974.1 - 8e-31 107.2 0.0 1.7e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR30974.1 - 6e-17 62.0 0.7 1.2e-15 57.8 0.1 3.2 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR30974.1 - 2.6e-08 34.0 0.0 1.1e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CAR30974.1 - 0.00015 20.6 0.0 0.00023 20.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SRP72 PF08492.12 CAR30975.1 - 3.7e-08 33.7 8.7 3.7e-08 33.7 8.7 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.6 CAR30975.1 - 7.9e-06 26.1 1.7 0.0023 18.2 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CAR30975.1 - 1.3e-05 25.3 1.3 0.8 10.0 0.0 3.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 SRP_TPR_like PF17004.5 CAR30975.1 - 3.7e-05 23.7 7.5 0.00033 20.7 3.0 3.8 3 1 0 3 3 3 1 Putative TPR-like repeat TPR_2 PF07719.17 CAR30975.1 - 0.028 14.5 4.9 11 6.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CAR30975.1 - 0.038 14.8 0.0 1.6e+02 3.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DDE_Tnp_IS1595 PF12762.7 CAR30975.1 - 0.35 10.9 0.1 0.35 10.9 0.1 1.8 2 0 0 2 2 2 0 ISXO2-like transposase domain TPR_19 PF14559.6 CAR30975.1 - 3.8 8.1 5.4 54 4.4 0.6 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat UPF0113_N PF17833.1 CAR30976.1 - 2.4e-29 101.7 0.0 3.6e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CAR30976.1 - 7e-26 90.3 0.0 1.4e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 UPF0113 PUA domain PseudoU_synth_1 PF01416.20 CAR30977.1 - 2.6e-12 47.2 0.0 5.8e-11 42.8 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 CAR30977.1 - 0.017 15.0 0.1 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Med15_fungi PF05397.12 CAR30977.1 - 0.55 10.5 2.9 0.34 11.2 0.4 1.9 2 0 0 2 2 2 0 Mediator complex subunit 15 DAP3 PF10236.9 CAR30978.1 - 6.1e-83 278.6 2.2 6.6e-83 278.4 1.3 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CAR30978.1 - 7.2e-06 26.5 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CAR30978.1 - 0.0037 17.2 0.0 0.0088 16.0 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CAR30978.1 - 0.0043 17.3 0.0 0.038 14.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CAR30978.1 - 0.014 15.3 0.0 0.37 10.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 CAR30978.1 - 0.022 13.8 0.4 0.27 10.2 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CAR30978.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CAR30978.1 - 0.032 14.2 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 CAR30978.1 - 0.054 14.0 0.0 0.17 12.4 0.0 1.8 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.22 CAR30978.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 CAR30978.1 - 0.09 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CAR30978.1 - 0.16 11.5 0.0 1 8.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain mRNA_cap_enzyme PF01331.19 CAR30979.1 - 1.1e-64 217.8 0.0 2.1e-64 217.0 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CAR30979.1 - 2.4e-33 115.0 0.1 4.5e-33 114.1 0.1 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CAR30979.1 - 2.3e-06 27.4 0.0 0.0011 18.7 0.0 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DUF4420 PF14390.6 CAR30979.1 - 0.047 12.9 0.5 0.3 10.3 0.2 2.0 2 0 0 2 2 2 0 Putative PD-(D/E)XK family member, (DUF4420) BAH PF01426.18 CAR30980.1 - 3.2e-18 65.8 1.6 9e-18 64.3 0.6 2.3 2 0 0 2 2 2 1 BAH domain zf-HC5HC2H_2 PF13832.6 CAR30980.1 - 3.8e-15 56.0 20.1 6.4e-14 52.1 3.3 4.0 3 0 0 3 3 3 2 PHD-zinc-finger like domain PHD PF00628.29 CAR30980.1 - 7e-13 48.3 55.0 1e-07 31.7 11.2 6.2 7 0 0 7 7 7 3 PHD-finger zf-HC5HC2H PF13771.6 CAR30980.1 - 1.8e-10 40.9 23.1 2.1e-08 34.3 2.1 4.5 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 CAR30980.1 - 8.2e-06 25.3 26.3 7.9e-05 22.1 3.4 5.0 5 0 0 5 5 5 3 PHD-finger C1_1 PF00130.22 CAR30980.1 - 0.0071 16.2 1.2 0.0071 16.2 1.2 6.4 6 1 1 7 7 7 4 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.31 CAR30980.1 - 0.0082 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_2 PF03107.16 CAR30980.1 - 6.4 7.2 50.8 0.11 12.8 1.3 6.1 6 0 0 6 6 6 0 C1 domain LRR_9 PF14580.6 CAR30981.1 - 3e-14 52.9 1.1 5.1e-14 52.2 1.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CAR30981.1 - 1.3e-05 25.4 13.4 0.006 17.0 2.5 3.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CAR30981.1 - 0.0019 17.9 11.5 0.024 14.4 5.6 3.2 1 1 3 4 4 4 4 Leucine rich repeat DUF4277 PF14104.6 CAR30981.1 - 0.071 13.5 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4277) LRR_6 PF13516.6 CAR30981.1 - 0.74 10.0 6.6 9.2 6.6 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat HK PF02110.15 CAR30982.1 - 7.9e-88 294.0 0.3 1.3e-87 293.3 0.1 1.4 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 CAR30982.1 - 6.7e-60 201.5 0.0 1.1e-59 200.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Ubiq_cyt_C_chap PF03981.12 CAR30983.1 - 3.5e-43 147.1 0.7 5.4e-43 146.5 0.7 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone WAC_Acf1_DNA_bd PF10537.9 CAR30984.1 - 1.6e-34 118.5 0.9 1.6e-34 118.5 0.9 2.8 3 0 0 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CAR30984.1 - 4.7e-11 43.1 0.1 4.7e-11 43.1 0.1 5.0 4 1 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 CAR30984.1 - 6.2e-08 32.8 1.3 2.5e-07 30.9 0.5 2.4 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 CAR30984.1 - 0.0035 16.8 0.2 0.013 15.0 0.2 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 RIBIOP_C PF04950.12 CAR30985.1 - 1.1e-87 294.2 0.2 1.1e-87 294.2 0.2 2.2 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CAR30985.1 - 8.1e-28 96.3 0.0 3e-27 94.5 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_33 PF13671.6 CAR30985.1 - 1.4e-06 28.5 0.0 4.1e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CAR30985.1 - 1.2e-05 25.6 0.0 3.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CAR30985.1 - 1.3e-05 25.7 0.0 3.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CAR30985.1 - 8.7e-05 23.0 0.0 0.00021 21.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 CAR30985.1 - 0.0002 21.0 3.5 0.00066 19.3 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 CAR30985.1 - 0.0091 15.2 0.3 0.074 12.2 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.6 CAR30985.1 - 0.022 15.1 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CAR30985.1 - 0.023 14.5 0.0 0.023 14.5 0.0 3.9 3 1 1 4 4 4 0 AAA domain NACHT PF05729.12 CAR30985.1 - 0.042 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CAR30985.1 - 0.047 14.1 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 CAR30985.1 - 0.047 13.8 0.1 0.18 11.9 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CAR30985.1 - 0.047 14.2 0.7 0.32 11.5 0.0 2.7 3 0 0 3 3 3 0 ABC transporter AAA_7 PF12775.7 CAR30985.1 - 0.048 13.2 0.0 0.048 13.2 0.0 1.8 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 CAR30985.1 - 0.056 13.2 0.8 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CAR30985.1 - 0.058 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CAR30985.1 - 0.077 13.0 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CAR30985.1 - 0.17 12.5 0.0 0.17 12.5 0.0 3.5 4 0 0 4 4 3 0 AAA domain Arf PF00025.21 CAR30986.1 - 6e-66 221.2 0.0 6.8e-66 221.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CAR30986.1 - 6.5e-09 35.4 0.5 1.4e-05 24.4 0.1 2.7 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CAR30986.1 - 2.7e-08 33.5 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CAR30986.1 - 1e-07 31.7 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR30986.1 - 1.8e-06 28.2 0.0 5.1e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CAR30986.1 - 2.1e-05 24.6 0.0 2.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CAR30986.1 - 0.0002 20.8 0.0 0.00023 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CAR30986.1 - 0.00021 20.9 0.1 0.0032 17.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CAR30986.1 - 0.19 11.5 0.0 0.45 10.2 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Cyclin PF08613.11 CAR30987.1 - 4.7e-17 62.8 0.5 1.2e-16 61.5 0.5 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CAR30987.1 - 0.0011 18.8 1.5 0.0029 17.3 1.5 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain Hormone_3 PF00159.18 CAR30987.1 - 0.032 14.3 0.2 0.073 13.2 0.1 1.7 2 0 0 2 2 2 0 Pancreatic hormone peptide Ribosomal_L1 PF00687.21 CAR30988.1 - 3.4e-43 147.8 0.7 3.9e-43 147.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family FtsJ PF01728.19 CAR30989.1 - 1.6e-51 174.9 0.0 2.1e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CAR30989.1 - 0.00035 20.5 0.0 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR30989.1 - 0.011 15.5 0.0 0.17 11.7 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 CAR30989.1 - 0.089 13.5 0.0 0.37 11.5 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Coatomer_WDAD PF04053.14 CAR30990.1 - 2e-159 531.4 0.0 2.8e-159 530.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CAR30990.1 - 5.6e-35 118.8 7.0 1.3e-06 29.0 0.0 8.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR30990.1 - 5.1e-08 33.1 0.0 2.9 8.2 0.0 6.8 4 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CAR30990.1 - 0.00037 20.5 0.0 3.3 7.8 0.0 4.6 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.21 CAR30990.1 - 0.001 18.9 4.1 0.3 11.1 0.0 4.5 6 0 0 6 6 6 2 PQQ enzyme repeat Nup160 PF11715.8 CAR30990.1 - 0.0023 16.6 2.7 1.7 7.2 0.0 3.7 2 2 2 4 4 4 2 Nucleoporin Nup120/160 MetallophosC PF16370.5 CAR30990.1 - 0.016 15.5 0.1 0.35 11.1 0.0 2.9 2 1 1 3 3 3 0 C terminal of Calcineurin-like phosphoesterase Clathrin PF00637.20 CAR30990.1 - 0.13 12.1 0.2 2.3 8.1 0.0 2.4 1 1 1 2 2 2 0 Region in Clathrin and VPS TPR_2 PF07719.17 CAR30990.1 - 0.33 11.2 1.1 41 4.6 0.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat EPL1 PF10513.9 CAR30991.1 - 0.035 14.5 7.4 0.039 14.4 6.6 1.6 1 1 0 1 1 1 0 Enhancer of polycomb-like Striatin PF08232.12 CAR30991.1 - 0.048 14.3 9.7 1.3 9.6 2.2 2.6 3 0 0 3 3 3 0 Striatin family Secretin_N_2 PF07655.13 CAR30991.1 - 0.49 11.0 15.0 0.4 11.3 8.4 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain TRP PF06011.12 CAR30992.1 - 2.7e-155 517.3 36.1 3.4e-155 517.0 36.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CAR30992.1 - 2.1e-38 131.9 1.4 3.5e-38 131.1 1.4 1.4 1 0 0 1 1 1 1 ML-like domain YaeQ PF07152.12 CAR30992.1 - 0.021 14.4 0.2 0.06 12.9 0.0 1.8 2 0 0 2 2 2 0 YaeQ protein E3_UbLigase_EDD PF11547.8 CAR30992.1 - 0.2 11.4 0.1 0.41 10.4 0.1 1.4 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD Lon_C PF05362.13 CAR30993.1 - 2.3e-42 144.9 0.6 7.4e-42 143.2 0.6 1.9 1 1 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CAR30993.1 - 1.2e-19 71.1 0.0 3.4e-19 69.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 CAR30993.1 - 3.2e-10 40.2 0.3 3.2e-10 40.2 0.3 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 CAR30993.1 - 2.5e-08 33.8 0.4 8.6e-08 32.1 0.4 1.9 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 CAR30993.1 - 3.2e-07 30.4 0.0 1.4e-06 28.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 CAR30993.1 - 1.6e-05 24.0 0.1 0.00027 20.0 0.0 2.1 2 0 0 2 2 2 1 PrkA AAA domain AAA_3 PF07726.11 CAR30993.1 - 7.8e-05 22.5 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CAR30993.1 - 8.1e-05 23.1 0.0 0.00021 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CAR30993.1 - 0.00022 21.0 0.0 0.00067 19.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CAR30993.1 - 0.00042 20.5 0.0 0.0024 18.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CAR30993.1 - 0.00068 19.9 0.0 0.012 15.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 CAR30993.1 - 0.002 18.1 0.0 0.0076 16.2 0.0 2.0 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 CAR30993.1 - 0.0062 15.9 0.0 0.043 13.2 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 CAR30993.1 - 0.011 15.6 0.1 0.04 13.8 0.0 2.0 1 1 1 2 2 2 0 NTPase AAA_7 PF12775.7 CAR30993.1 - 0.015 14.9 0.1 0.088 12.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF4335 PF14233.6 CAR30993.1 - 0.015 15.2 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Sigma54_activ_2 PF14532.6 CAR30993.1 - 0.018 15.1 0.0 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 CAR30993.1 - 0.02 15.0 0.0 0.14 12.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CAR30993.1 - 0.022 14.9 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CAR30993.1 - 0.029 14.7 0.0 0.19 12.1 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 CAR30993.1 - 0.035 13.3 0.0 0.088 12.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 CAR30993.1 - 0.036 13.8 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CAR30993.1 - 0.042 13.6 0.0 0.46 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CAR30993.1 - 0.043 14.4 0.3 0.14 12.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 CAR30993.1 - 0.057 13.1 0.0 0.15 11.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain KTI12 PF08433.10 CAR30993.1 - 0.07 12.6 0.2 0.2 11.1 0.0 1.8 2 0 0 2 2 1 0 Chromatin associated protein KTI12 TniB PF05621.11 CAR30993.1 - 0.1 12.0 0.0 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_19 PF13245.6 CAR30993.1 - 0.13 12.6 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CAR30993.1 - 2.6 8.5 0.0 2.6 8.5 0.0 3.4 1 1 1 2 2 1 0 AAA domain UPF0061 PF02696.14 CAR30994.1 - 2.6e-144 481.5 0.0 3.1e-144 481.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Swm2 PF17083.5 CAR30994.1 - 0.022 14.8 0.2 0.045 13.7 0.2 1.5 1 0 0 1 1 1 0 Nucleolar protein Swm2 GCR1_C PF12550.8 CAR30995.1 - 2.1e-22 79.2 0.3 3.8e-22 78.4 0.3 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Merozoite_SPAM PF07133.11 CAR30995.1 - 0.022 14.7 9.0 0.046 13.7 9.0 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 CAR30995.1 - 1.1 7.4 8.7 1.7 6.9 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein ARID PF01388.21 CAR30997.1 - 3.8e-19 69.2 1.0 1.2e-18 67.5 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjC PF02373.22 CAR30997.1 - 9.6e-17 61.5 1.5 2.6e-10 40.7 0.2 3.3 2 0 0 2 2 2 2 JmjC domain, hydroxylase PHD PF00628.29 CAR30997.1 - 3.1e-07 30.2 8.2 3.1e-07 30.2 8.2 2.0 2 0 0 2 2 2 1 PHD-finger PLU-1 PF08429.11 CAR30997.1 - 1.7e-06 27.5 4.3 1.7e-06 27.5 4.3 2.3 2 0 0 2 2 2 1 PLU-1-like protein PHD_4 PF16866.5 CAR30997.1 - 0.057 13.5 4.3 0.26 11.4 4.3 2.2 1 1 0 1 1 1 0 PHD-finger C1_1 PF00130.22 CAR30997.1 - 0.1 12.5 3.0 0.34 10.8 3.0 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 CAR30997.1 - 0.47 10.7 4.7 2 8.8 4.7 2.1 1 0 0 1 1 1 0 PHD-like zinc-binding domain Cation_efflux PF01545.21 CAR30998.1 - 2.9e-40 138.2 10.2 3.7e-40 137.8 10.2 1.2 1 0 0 1 1 1 1 Cation efflux family Polysacc_synt_4 PF04669.13 CAR30999.1 - 6.2e-19 68.3 0.9 8.5e-17 61.3 0.9 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Cullin_binding PF03556.15 CAR30999.1 - 0.0071 16.8 0.5 0.012 16.1 0.5 1.4 1 0 0 1 1 1 1 Cullin binding DUF615 PF04751.14 CAR30999.1 - 0.052 13.5 0.2 0.071 13.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) NitrOD1 PF18549.1 CAR30999.1 - 0.12 12.4 0.2 0.24 11.4 0.2 1.5 1 0 0 1 1 1 0 Nitrosopumilus output domain 1 MoCF_biosynth PF00994.24 CAR31000.1 - 1e-32 112.7 0.0 1.5e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain PCI PF01399.27 CAR31000.1 - 0.075 13.5 0.2 0.8 10.3 0.0 2.6 3 1 0 3 3 3 0 PCI domain ABC_tran PF00005.27 CAR31001.1 - 8e-48 162.4 0.0 4.8e-25 88.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CAR31001.1 - 6.9e-13 49.1 3.2 0.0019 18.1 0.8 4.7 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR31001.1 - 1.7e-11 44.0 0.0 0.003 17.0 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 CAR31001.1 - 1.8e-08 34.1 1.0 4.8e-08 32.8 1.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RsgA_GTPase PF03193.16 CAR31001.1 - 7e-07 29.3 0.1 0.018 15.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CAR31001.1 - 1.3e-06 28.1 0.2 0.025 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CAR31001.1 - 2.1e-06 27.8 0.3 0.028 14.5 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CAR31001.1 - 4.2e-05 24.1 11.1 0.013 16.0 0.0 3.9 5 0 0 5 5 3 2 AAA domain AAA_22 PF13401.6 CAR31001.1 - 6.1e-05 23.3 0.1 0.33 11.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CAR31001.1 - 9.5e-05 22.7 0.1 0.5 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 CAR31001.1 - 0.00012 22.3 1.3 0.1 12.7 0.0 3.6 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_16 PF13191.6 CAR31001.1 - 0.00022 21.7 0.4 0.42 11.0 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 CAR31001.1 - 0.00037 20.8 0.1 2.5 8.5 0.0 3.3 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 CAR31001.1 - 0.00068 20.2 0.7 0.68 10.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CAR31001.1 - 0.0016 18.4 0.8 1.2 9.0 0.2 3.1 2 1 0 2 2 2 1 NACHT domain MeaB PF03308.16 CAR31001.1 - 0.0018 17.3 0.1 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 CAR31001.1 - 0.0029 17.6 0.0 5.1 7.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CAR31001.1 - 0.003 17.6 0.3 0.12 12.4 0.0 2.9 2 1 0 2 2 2 1 Dynamin family AAA PF00004.29 CAR31001.1 - 0.0032 17.9 0.1 5.7 7.4 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CAR31001.1 - 0.0036 17.5 0.0 4.2 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CAR31001.1 - 0.0044 16.8 0.2 2.5 7.8 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 CAR31001.1 - 0.01 15.4 0.0 4.9 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CAR31001.1 - 0.019 14.9 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 CAR31001.1 - 0.019 14.2 0.1 0.63 9.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 CAR31001.1 - 0.021 14.0 0.1 2.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 CAR31001.1 - 0.034 13.9 0.1 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CAR31001.1 - 0.034 13.8 9.4 0.58 9.8 0.1 4.2 4 1 0 4 4 4 0 AAA ATPase domain Roc PF08477.13 CAR31001.1 - 0.036 14.3 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 CAR31001.1 - 0.04 13.8 0.1 13 5.7 0.1 3.1 3 0 0 3 3 3 0 NTPase CLP1_P PF16575.5 CAR31001.1 - 0.05 13.4 0.0 5.7 6.7 0.0 2.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 CAR31001.1 - 0.062 13.2 0.1 22 4.9 0.0 3.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_13 PF13166.6 CAR31001.1 - 0.076 11.6 3.5 1.2 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 CAR31001.1 - 0.084 12.9 0.1 16 5.5 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 CAR31001.1 - 0.092 12.4 0.3 0.91 9.2 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase MukB PF04310.12 CAR31001.1 - 0.13 12.1 0.0 18 5.0 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal DrrA_P4M PF14860.6 CAR31002.1 - 0.017 15.0 0.4 0.039 13.8 0.4 1.6 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Glycos_transf_2 PF00535.26 CAR31003.1 - 2.4e-27 95.8 0.0 3.2e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CAR31003.1 - 7e-08 32.6 0.0 1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CAR31003.1 - 0.0043 17.5 0.0 0.0081 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 CAR31003.1 - 0.03 13.8 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 mRNA_triPase PF02940.15 CAR31004.1 - 5.3e-62 209.4 0.1 9.8e-62 208.5 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain HSP20 PF00011.21 CAR31006.1 - 2.5e-19 69.3 2.2 3.9e-19 68.7 2.2 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CAR31006.1 - 4e-08 32.7 0.0 6.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA BON PF04972.17 CAR31006.1 - 0.034 14.5 0.2 4.5 7.6 0.1 2.7 2 0 0 2 2 2 0 BON domain GPAT_N PF14829.6 CAR31006.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Fas_alpha_ACP PF18325.1 CAR31007.1 - 2.3e-73 245.9 0.1 7.1e-73 244.3 0.1 1.9 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 CAR31007.1 - 8.9e-68 227.9 1.6 1.3e-67 227.3 0.3 2.0 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 CAR31007.1 - 8e-21 74.8 0.0 1.8e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 CAR31007.1 - 6e-20 71.5 0.0 1.3e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 CAR31007.1 - 2.3e-13 50.2 0.0 8e-13 48.4 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 CAR31007.1 - 0.0011 19.0 0.0 0.0028 17.6 0.0 1.7 1 0 0 1 1 1 1 KR domain DEC-1_N PF04625.13 CAR31007.1 - 2.7 6.9 14.9 7 5.5 14.9 1.6 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Syntaxin PF00804.25 CAR31008.1 - 3.6e-20 72.5 14.0 3.6e-20 72.5 14.0 2.1 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 CAR31008.1 - 1.4e-15 57.0 2.2 1.4e-15 57.0 2.2 2.9 4 0 0 4 4 3 1 SNARE domain DUF2207 PF09972.9 CAR31008.1 - 0.00025 19.9 0.2 0.00054 18.9 0.1 1.6 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) Synaptobrevin PF00957.21 CAR31008.1 - 0.00037 20.2 2.5 0.00037 20.2 2.5 2.0 2 0 0 2 2 2 1 Synaptobrevin BLOC1_2 PF10046.9 CAR31008.1 - 0.00076 19.7 4.2 0.43 10.9 0.0 2.9 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 CAR31008.1 - 0.00086 19.4 6.4 0.035 14.1 0.2 2.3 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 CAR31008.1 - 0.0009 19.5 4.1 0.0009 19.5 4.1 3.0 3 1 0 3 3 2 1 Bacterial protein of unknown function (DUF948) T2SSF PF00482.23 CAR31008.1 - 0.011 15.6 1.2 0.027 14.4 0.2 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F AATase PF07247.12 CAR31008.1 - 0.013 14.1 0.8 0.032 12.8 0.1 1.8 2 0 0 2 2 2 0 Alcohol acetyltransferase SlyX PF04102.12 CAR31008.1 - 0.018 15.6 3.6 0.018 15.6 3.6 2.3 2 1 0 2 2 2 0 SlyX SKA1 PF07160.12 CAR31008.1 - 0.02 14.8 3.2 0.02 14.8 3.2 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 SLATT_5 PF18160.1 CAR31008.1 - 0.026 13.9 0.8 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PBP1_TM PF14812.6 CAR31008.1 - 0.034 14.5 0.2 0.034 14.5 0.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Use1 PF09753.9 CAR31008.1 - 0.034 13.9 9.1 0.051 13.3 9.1 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 UPF0184 PF03670.13 CAR31008.1 - 0.072 13.5 0.2 0.072 13.5 0.2 3.4 2 2 3 5 5 5 0 Uncharacterised protein family (UPF0184) DUF2951 PF11166.8 CAR31008.1 - 0.079 13.2 11.1 0.15 12.3 0.5 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2951) DotU PF09850.9 CAR31008.1 - 0.19 11.4 3.4 1.6 8.4 0.0 2.7 2 2 0 2 2 2 0 Type VI secretion system protein DotU DUF745 PF05335.13 CAR31008.1 - 0.29 10.8 14.9 0.016 14.9 8.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 CAR31008.1 - 0.52 10.5 12.0 0.29 11.3 1.6 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CREPT PF16566.5 CAR31008.1 - 1.5 9.0 11.7 1.8 8.7 1.9 2.5 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1664 PF07889.12 CAR31008.1 - 1.6 8.8 7.3 0.39 10.8 1.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 CAR31008.1 - 2.2 8.8 13.7 0.069 13.6 4.0 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF883 PF05957.13 CAR31008.1 - 2.8 8.6 9.6 1.1 10.0 0.9 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF755 PF05501.11 CAR31008.1 - 4.5 7.6 9.9 9.8 6.5 1.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF755) DUF4094 PF13334.6 CAR31008.1 - 5 7.6 6.7 1.4 9.4 0.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) FUSC PF04632.12 CAR31008.1 - 5.1 5.5 9.4 0.94 7.9 1.0 1.9 1 1 1 2 2 2 0 Fusaric acid resistance protein family T3SSipB PF16535.5 CAR31008.1 - 7.5 7.0 12.5 1 9.8 2.7 2.6 1 1 1 3 3 3 0 Type III cell invasion protein SipB Mis14 PF08641.12 CAR31009.1 - 2e-14 54.0 2.1 3.8e-14 53.2 2.0 1.6 1 1 0 1 1 1 1 Kinetochore protein Mis14 like ERM PF00769.19 CAR31009.1 - 0.22 11.3 4.6 0.3 10.9 4.6 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ATP-synt_C PF00137.21 CAR31010.1 - 1.7e-33 114.8 29.7 1.3e-19 70.2 8.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TIP49 PF06068.13 CAR31011.1 - 8.4e-157 521.8 3.2 1e-156 521.5 3.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CAR31011.1 - 1.9e-24 85.6 0.6 6.3e-24 83.9 0.5 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 CAR31011.1 - 1.1e-07 32.4 0.7 0.00021 21.7 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CAR31011.1 - 5.9e-07 29.4 0.3 0.0037 17.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 CAR31011.1 - 5.5e-06 25.9 0.2 1.2e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CAR31011.1 - 0.00055 20.4 0.1 0.0022 18.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CAR31011.1 - 0.002 18.4 0.0 0.24 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CAR31011.1 - 0.0037 17.6 0.7 0.045 14.1 0.7 2.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CAR31011.1 - 0.011 15.1 0.6 0.25 10.7 0.2 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CAR31011.1 - 0.014 15.0 0.1 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CAR31011.1 - 0.024 14.6 0.3 5.1 7.1 0.0 3.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CAR31011.1 - 0.067 13.4 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CAR31011.1 - 0.074 12.8 0.1 9.2 5.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CAR31011.1 - 0.19 11.2 0.7 0.76 9.3 0.0 2.2 3 0 0 3 3 3 0 P-loop containing dynein motor region Pkinase PF00069.25 CAR31012.1 - 9e-35 120.3 0.0 1.9e-25 89.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CAR31012.1 - 5.5e-16 58.6 0.0 3.4e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CAR31012.1 - 0.065 12.5 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like DUF3255 PF11631.8 CAR31012.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3255) eIF-5_eIF-2B PF01873.17 CAR31014.1 - 5.5e-38 129.5 0.1 9.8e-38 128.6 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.15 CAR31014.1 - 0.018 14.9 0.1 0.13 12.1 0.0 2.4 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region TF_Zn_Ribbon PF08271.12 CAR31014.1 - 0.032 13.7 0.1 0.067 12.7 0.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding Nas2_N PF18265.1 CAR31014.1 - 0.16 11.9 0.3 0.88 9.5 0.2 2.2 2 0 0 2 2 2 0 Nas2 N_terminal domain DUF2752 PF10825.8 CAR31014.1 - 0.21 11.7 0.0 0.35 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Arc_trans_TRASH PF08394.10 CAR31014.1 - 2.9 8.3 5.8 26 5.3 2.0 2.6 1 1 1 2 2 2 0 Archaeal TRASH domain Ank_4 PF13637.6 CAR31015.1 - 9.2e-18 64.4 0.0 1.5e-12 47.8 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CAR31015.1 - 2.1e-15 56.6 0.2 9.5e-09 35.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CAR31015.1 - 6.5e-15 55.5 0.1 1.8e-14 54.1 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CAR31015.1 - 1.6e-11 43.3 0.0 0.00053 20.2 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CAR31015.1 - 1e-10 41.5 0.0 0.00029 21.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat RTP1_C1 PF10363.9 CAR31016.1 - 5.8e-27 94.1 1.0 5.8e-27 94.1 1.0 4.2 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 CAR31016.1 - 0.056 13.1 0.6 0.26 11.0 0.6 2.3 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 PMC2NT PF08066.12 CAR31016.1 - 2.6 8.8 9.3 0.57 10.9 1.8 3.7 3 0 0 3 3 3 0 PMC2NT (NUC016) domain HSP90 PF00183.18 CAR31017.1 - 2.7e-217 722.8 34.7 3.9e-217 722.3 34.7 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CAR31017.1 - 5.6e-14 52.6 0.0 1.1e-13 51.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CAR31017.1 - 2.1e-10 40.6 0.0 6.9e-10 38.9 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Atg14 PF10186.9 CAR31017.1 - 4.8 6.2 6.9 13 4.7 6.9 1.7 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tau95 PF09734.9 CAR31017.1 - 8.3 7.2 9.9 1.9 9.3 4.2 2.6 3 0 0 3 3 3 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain TBCC PF07986.12 CAR31018.1 - 3.5e-09 36.4 4.7 4.2e-07 29.7 1.4 2.3 1 1 0 2 2 2 2 Tubulin binding cofactor C DUF2321 PF10083.9 CAR31018.1 - 0.16 11.6 4.1 3.3 7.3 0.4 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) SpoOE-like PF09388.10 CAR31018.1 - 2.7 8.0 5.2 0.64 10.0 1.7 1.8 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein RasGAP_C PF03836.15 CAR31019.1 - 1.7e-30 106.0 6.2 1.7e-30 106.0 6.2 2.2 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.19 CAR31019.1 - 1.8e-15 57.3 1.7 1.8e-15 57.3 1.7 3.0 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 CAR31019.1 - 4.6e-12 46.1 0.3 1.6e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 CAR31019.1 - 4.6e-05 22.9 24.9 0.51 10.3 0.1 8.5 9 0 0 9 9 9 4 IQ calmodulin-binding motif Ada3 PF10198.9 CAR31019.1 - 0.026 14.6 0.5 0.39 10.9 0.6 2.9 3 0 0 3 3 3 0 Histone acetyltransferases subunit 3 ArsR PF09824.9 CAR31019.1 - 0.064 12.8 0.4 0.3 10.7 0.4 2.2 1 0 0 1 1 1 0 ArsR transcriptional regulator NPV_P10 PF05531.12 CAR31019.1 - 0.91 10.0 7.2 0.79 10.2 0.1 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein GrpE PF01025.19 CAR31019.1 - 2.1 8.0 6.8 0.99 9.0 0.9 2.9 2 1 0 2 2 2 0 GrpE RINGv PF12906.7 CAR31020.1 - 0.0033 17.5 6.2 0.0033 17.5 6.2 2.3 2 0 0 2 2 2 1 RING-variant domain DUF3797 PF12677.7 CAR31020.1 - 0.56 10.1 0.1 0.56 10.1 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) FANCL_C PF11793.8 CAR31020.1 - 2.8 8.2 13.3 12 6.2 6.3 3.3 3 0 0 3 3 3 0 FANCL C-terminal domain SRP68 PF16969.5 CAR31021.1 - 1.3e-66 225.8 21.0 1.7e-66 225.4 21.0 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 H-kinase_dim PF02895.14 CAR31021.1 - 1.7 9.1 5.8 2.4 8.6 1.8 3.0 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF1104 PF06518.11 CAR31021.1 - 5.5 7.4 11.7 11 6.5 1.5 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1104) UAA PF08449.11 CAR31022.1 - 2e-35 122.5 11.6 2.3e-35 122.3 11.6 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 CAR31022.1 - 1.6e-06 27.7 9.9 0.00012 21.5 1.8 2.5 2 1 1 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.20 CAR31022.1 - 4e-06 27.1 21.5 3e-05 24.2 9.0 3.2 3 1 0 3 3 3 2 EamA-like transporter family MerC PF03203.14 CAR31022.1 - 3.8 8.0 11.2 1.6 9.2 0.3 3.1 2 1 1 3 3 3 0 MerC mercury resistance protein DUF2075 PF09848.9 CAR31023.1 - 1.9e-109 366.3 0.0 2.2e-109 366.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CAR31023.1 - 4.3e-07 30.3 0.0 1.4e-06 28.6 0.1 1.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 CAR31023.1 - 0.00024 21.5 0.0 0.00069 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CAR31023.1 - 0.00047 20.6 0.0 0.00093 19.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CAR31023.1 - 0.00066 19.4 0.1 0.0063 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 CAR31023.1 - 0.001 19.1 0.7 0.7 9.9 0.1 2.3 1 1 0 2 2 2 2 Type III restriction enzyme, res subunit TniB PF05621.11 CAR31023.1 - 0.0031 16.9 0.1 0.006 16.0 0.1 1.4 1 0 0 1 1 1 1 Bacterial TniB protein RsgA_GTPase PF03193.16 CAR31023.1 - 0.016 15.1 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 CAR31023.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CAR31023.1 - 0.023 14.6 0.1 0.039 13.9 0.1 1.5 1 1 0 1 1 1 0 NACHT domain PIF1 PF05970.14 CAR31023.1 - 0.026 13.7 0.1 0.049 12.8 0.0 1.6 1 1 0 1 1 1 0 PIF1-like helicase T2SSE PF00437.20 CAR31023.1 - 0.04 13.0 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 CAR31023.1 - 0.054 13.9 0.0 0.27 11.7 0.0 2.3 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 CAR31023.1 - 0.057 13.2 0.1 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CAR31023.1 - 0.063 12.6 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DAP3 PF10236.9 CAR31023.1 - 0.066 12.4 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_19 PF13245.6 CAR31023.1 - 0.079 13.3 0.1 4.9 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CAR31023.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Rhomboid PF01694.22 CAR31024.1 - 3.8e-20 72.4 8.1 6.4e-20 71.7 8.1 1.3 1 0 0 1 1 1 1 Rhomboid family DUF2975 PF11188.8 CAR31024.1 - 0.0027 17.6 2.3 0.0027 17.6 2.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2975) DUF1129 PF06570.11 CAR31024.1 - 0.01 15.3 0.6 0.015 14.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Ribosomal_S17 PF00366.20 CAR31025.1 - 2.7e-23 81.9 1.5 2.9e-23 81.8 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 SNCAIP_SNCA_bd PF16700.5 CAR31025.1 - 0.072 12.8 2.0 0.19 11.4 2.0 1.7 1 0 0 1 1 1 0 Synphilin-1 alpha-Synuclein-binding domain WD40 PF00400.32 CAR31026.1 - 2.8e-11 43.8 8.0 0.00083 20.1 0.1 4.8 4 1 0 4 4 4 3 WD domain, G-beta repeat GDC-P PF02347.16 CAR31027.1 - 1.6e-196 653.2 0.0 2.2e-184 613.3 0.0 3.1 2 1 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 CAR31027.1 - 5.3e-05 22.3 0.1 0.00021 20.4 0.1 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CAR31027.1 - 0.00027 20.3 0.0 0.00098 18.5 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CAR31027.1 - 0.00071 18.9 0.0 0.034 13.3 0.0 2.6 3 0 0 3 3 3 1 Aminotransferase class I and II MFS_1 PF07690.16 CAR31028.1 - 2.7e-23 82.5 13.0 3.9e-22 78.6 12.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sulfate_transp PF00916.20 CAR31028.1 - 0.085 11.6 3.9 1.6 7.4 0.4 2.5 3 0 0 3 3 3 0 Sulfate permease family RQC PF09382.10 CAR31029.1 - 2.8e-29 101.2 0.0 5.4e-29 100.3 0.0 1.5 1 0 0 1 1 1 1 RQC domain Helicase_Sgs1 PF11408.8 CAR31029.1 - 1e-23 83.2 0.1 3.4e-23 81.5 0.1 2.0 1 0 0 1 1 1 1 Sgs1 RecQ helicase Helicase_C PF00271.31 CAR31029.1 - 6.7e-22 77.9 0.6 5.2e-16 59.0 0.0 3.5 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 CAR31029.1 - 8.5e-21 74.5 0.1 8.1e-20 71.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CAR31029.1 - 2e-13 50.9 10.3 2e-13 50.9 10.3 2.5 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 CAR31029.1 - 3.6e-05 23.8 2.0 5.7e-05 23.2 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HRDC PF00570.23 CAR31029.1 - 0.0001 22.2 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 HRDC domain DUF3907 PF13047.6 CAR31029.1 - 0.072 13.1 0.2 0.24 11.4 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) Rhodanese PF00581.20 CAR31029.1 - 0.16 12.5 0.8 5 7.7 0.0 3.2 2 1 0 2 2 2 0 Rhodanese-like domain Fungal_trans PF04082.18 CAR31030.1 - 1.8e-23 82.9 0.2 3.2e-23 82.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 CAR31030.1 - 1.5e-14 53.9 2.8 3.9e-14 52.5 2.8 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.18 CAR31030.1 - 1.8e-08 34.3 17.0 3.7e-08 33.4 17.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.18 CAR31032.1 - 3.6e-48 164.1 0.8 3.6e-48 164.1 0.8 2.9 3 1 1 4 4 4 2 Rab-GTPase-TBC domain Cnn_1N PF07989.11 CAR31032.1 - 0.0004 20.5 3.0 0.0004 20.5 3.0 4.1 4 0 0 4 4 4 1 Centrosomin N-terminal motif 1 HOOK PF05622.12 CAR31032.1 - 0.06 11.5 20.9 0.035 12.3 5.7 2.4 1 1 1 2 2 2 0 HOOK protein IFP_35_N PF07334.13 CAR31032.1 - 1.6 8.8 5.8 24 5.1 1.5 3.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF1664 PF07889.12 CAR31032.1 - 1.6 8.7 10.7 5.7 7.0 7.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ACOX PF01756.19 CAR31033.1 - 8.2e-37 126.5 0.1 1.6e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CAR31033.1 - 2.3e-18 66.2 0.0 3.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 CAR31033.1 - 1.1e-10 42.2 0.1 3.1e-10 40.7 0.1 1.8 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 CAR31033.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Acetyltransf_19 PF18015.1 CAR31033.1 - 0.041 14.1 0.0 0.14 12.4 0.1 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Clathrin PF00637.20 CAR31034.1 - 8.7e-185 606.0 55.8 1.4e-32 112.6 0.1 8.5 10 0 0 10 10 10 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 CAR31034.1 - 1.1e-27 94.9 9.6 1.6e-08 34.4 0.3 5.9 5 0 0 5 5 5 5 Clathrin propeller repeat Clathrin_H_link PF13838.6 CAR31034.1 - 1.6e-26 91.9 0.2 6.4e-26 90.0 0.2 2.1 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.10 CAR31034.1 - 6.7e-08 31.7 4.7 1.3e-07 30.9 0.4 3.0 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Vps39_1 PF10366.9 CAR31034.1 - 3.5e-05 24.0 13.0 1.1 9.5 0.0 7.7 8 0 0 8 8 8 2 Vacuolar sorting protein 39 domain 1 PPR PF01535.20 CAR31034.1 - 0.028 14.7 1.4 1.1e+02 3.4 0.0 5.7 4 1 1 5 5 5 0 PPR repeat TPR_19 PF14559.6 CAR31034.1 - 0.048 14.2 2.9 6.3 7.4 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CAR31034.1 - 0.21 11.7 8.5 61 4.0 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 CAR31034.1 - 4.1 7.8 8.1 10 6.5 0.2 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 CAR31034.1 - 4.9 7.6 8.1 5.5 7.5 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat FACT-Spt16_Nlob PF14826.6 CAR31035.1 - 9.2e-49 165.3 5.6 1.4e-48 164.7 0.3 3.3 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 CAR31035.1 - 3.9e-48 163.5 0.1 3.9e-48 163.5 0.1 2.1 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 CAR31035.1 - 7.6e-29 100.9 0.0 1.3e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CAR31035.1 - 2.2e-13 50.4 1.5 8.3e-13 48.6 0.1 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like AMPK1_CBM PF16561.5 CAR31036.1 - 2.1e-28 98.3 0.1 1.1e-27 96.0 0.0 2.1 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CAR31036.1 - 7.1e-27 93.5 1.0 2e-26 92.1 1.0 1.8 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain zf-C2H2 PF00096.26 CAR31037.1 - 1e-10 41.5 15.8 9.8e-07 28.9 2.6 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CAR31037.1 - 4.3e-10 39.6 16.8 2.3e-06 27.8 6.3 3.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CAR31037.1 - 3.9e-08 33.4 13.1 0.00021 21.8 2.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CAR31037.1 - 2.5e-05 24.4 5.9 0.0025 18.0 1.5 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CAR31037.1 - 0.0067 17.0 0.1 0.013 16.2 0.1 1.4 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-met PF12874.7 CAR31037.1 - 0.021 15.2 1.9 1.9 9.0 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 CAR31037.1 - 0.023 14.5 0.1 0.023 14.5 0.1 3.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 CAR31037.1 - 0.1 13.1 3.6 8.4 6.9 0.3 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF629 PF04780.12 CAR31037.1 - 0.36 9.3 3.6 1 7.8 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2HC_2 PF13913.6 CAR31037.1 - 0.6 10.1 10.9 1.3 9.0 1.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_8 PF15909.5 CAR31037.1 - 0.75 10.1 0.1 0.75 10.1 0.1 2.4 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CAR31037.1 - 0.88 9.6 16.0 0.41 10.7 2.0 3.3 3 1 0 3 3 3 0 C2H2-type zinc finger LSM PF01423.22 CAR31038.1 - 7.2e-18 64.0 0.2 1.2e-17 63.3 0.2 1.4 1 0 0 1 1 1 1 LSM domain DA1-like PF12315.8 CAR31038.1 - 0.098 12.0 1.3 0.13 11.6 1.3 1.3 1 0 0 1 1 1 0 Protein DA1 CHZ PF09649.10 CAR31039.1 - 2.6e-19 68.4 2.2 2.6e-19 68.4 2.2 2.4 2 0 0 2 2 2 1 Histone chaperone domain CHZ Ras PF00071.22 CAR31040.1 - 1.1e-60 203.9 0.1 1.3e-60 203.7 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CAR31040.1 - 3.3e-34 117.7 0.1 5e-34 117.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CAR31040.1 - 6.7e-13 48.5 0.0 8.7e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CAR31040.1 - 1.5e-06 28.2 0.1 2.4e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CAR31040.1 - 0.00051 19.6 0.1 0.002 17.7 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CAR31040.1 - 0.0017 17.7 0.0 0.0021 17.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CAR31040.1 - 0.0039 17.1 0.1 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 CAR31040.1 - 0.0067 16.2 0.0 0.017 14.9 0.0 1.7 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 CAR31040.1 - 0.015 14.5 0.0 0.031 13.5 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain SRPRB PF09439.10 CAR31040.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CAR31040.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 CAR31040.1 - 0.017 14.4 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 CAR31040.1 - 0.022 15.1 0.0 0.058 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CAR31040.1 - 0.047 13.2 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CAR31040.1 - 0.06 13.1 0.1 0.099 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain DUF1128 PF06569.11 CAR31040.1 - 0.063 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) ABC_tran PF00005.27 CAR31040.1 - 0.065 13.7 0.4 0.1 13.1 0.5 1.5 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 CAR31040.1 - 0.11 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B zn-ribbon_14 PF16503.5 CAR31043.1 - 1.5e-17 62.8 5.1 1.5e-17 62.8 5.1 3.6 3 0 0 3 3 3 1 Zinc-ribbon ATP_bind_3 PF01171.20 CAR31043.1 - 1.9e-16 60.3 0.0 4.6e-16 59.1 0.0 1.6 1 1 0 1 1 1 1 PP-loop family CTU2 PF10288.9 CAR31043.1 - 3 8.1 5.9 2.4 8.4 0.2 2.7 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 PX PF00787.24 CAR31044.1 - 1.1e-13 51.2 1.4 1.4e-13 50.8 0.3 1.8 2 0 0 2 2 2 1 PX domain Use1 PF09753.9 CAR31044.1 - 0.0061 16.3 11.7 0.0092 15.7 11.7 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 WD40 PF00400.32 CAR31045.1 - 5.7e-11 42.8 18.3 1e-06 29.3 0.2 6.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CAR31045.1 - 4.7e-09 36.4 0.0 0.0027 18.0 0.0 3.2 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CAR31045.1 - 0.002 17.2 0.0 2.1 7.2 0.0 3.5 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CAR31045.1 - 0.038 13.3 0.0 4 6.7 0.0 2.3 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal BBS2_Mid PF14783.6 CAR31045.1 - 0.07 13.2 0.0 47 4.1 0.0 3.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Amidase PF01425.21 CAR31046.1 - 1.4e-32 113.2 0.1 2.2e-32 112.6 0.1 1.2 1 0 0 1 1 1 1 Amidase Cyclin PF08613.11 CAR31047.1 - 0.0026 18.2 0.4 0.0026 18.2 0.4 3.2 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CAR31047.1 - 0.0062 16.3 0.0 0.0062 16.3 0.0 2.3 3 0 0 3 3 3 1 Cyclin, N-terminal domain Suf PF05843.14 CAR31047.1 - 7.1 6.5 15.8 13 5.7 15.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) POTRA_TamA_1 PF17243.2 CAR31047.1 - 9.3 6.4 12.2 3 8.0 9.1 1.7 1 1 0 1 1 1 0 POTRA domain TamA domain 1 Kinesin PF00225.23 CAR31048.1 - 1.1e-114 382.9 0.3 1.6e-114 382.3 0.3 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CAR31048.1 - 9.8e-26 90.5 0.2 2.9e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding BolA PF01722.18 CAR31050.1 - 4e-16 59.1 0.0 6.6e-16 58.4 0.0 1.4 1 1 1 2 2 2 1 BolA-like protein NIF3 PF01784.18 CAR31051.1 - 4.7e-67 226.2 0.0 5.7e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF5364 PF17322.2 CAR31052.1 - 1e-60 205.3 14.5 1.1e-60 205.1 14.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5364) ABC_tran PF00005.27 CAR31054.1 - 9.6e-50 168.7 0.1 3.9e-25 88.9 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CAR31054.1 - 3e-21 75.2 0.6 3e-21 75.2 0.6 3.0 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 CAR31054.1 - 1.1e-19 71.4 4.3 2.8e-06 27.4 0.0 4.5 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CAR31054.1 - 2.5e-09 36.9 1.4 0.84 9.0 0.1 4.8 3 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CAR31054.1 - 1.8e-07 30.8 0.0 0.0061 16.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CAR31054.1 - 3.8e-07 30.2 0.2 0.00098 19.1 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 CAR31054.1 - 1e-06 29.1 0.0 0.058 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CAR31054.1 - 4.5e-06 26.7 0.0 0.012 15.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CAR31054.1 - 4.9e-06 27.1 0.0 0.12 12.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 CAR31054.1 - 8.8e-06 26.4 11.9 0.011 16.2 0.0 4.0 5 0 0 5 5 3 2 AAA domain AAA_33 PF13671.6 CAR31054.1 - 1.1e-05 25.6 0.0 0.084 13.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 CAR31054.1 - 1.6e-05 25.3 0.4 0.28 11.6 0.0 3.8 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CAR31054.1 - 1.7e-05 25.1 0.0 0.094 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CAR31054.1 - 2.6e-05 24.3 0.0 0.1 12.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 CAR31054.1 - 3.2e-05 24.3 0.1 0.38 11.2 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_16 PF13191.6 CAR31054.1 - 5.7e-05 23.6 0.1 0.069 13.5 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 CAR31054.1 - 6.7e-05 22.8 6.4 0.095 12.4 0.0 3.3 4 0 0 4 4 3 2 AAA ATPase domain NACHT PF05729.12 CAR31054.1 - 8.8e-05 22.5 0.1 0.34 10.8 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 CAR31054.1 - 0.00021 21.1 0.2 0.36 10.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 CAR31054.1 - 0.00061 19.8 0.0 0.89 9.4 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain Roc PF08477.13 CAR31054.1 - 0.0013 19.0 0.0 1.3 9.2 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 CAR31054.1 - 0.0018 17.4 0.0 1.3 8.0 0.0 2.4 2 0 0 2 2 2 2 MCM P-loop domain NB-ARC PF00931.22 CAR31054.1 - 0.0027 16.9 0.0 1 8.5 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain Dynamin_N PF00350.23 CAR31054.1 - 0.004 17.2 1.5 2.8 8.0 0.0 3.8 2 1 1 3 3 3 1 Dynamin family AAA_25 PF13481.6 CAR31054.1 - 0.0046 16.6 0.1 1.3 8.5 0.0 3.3 2 1 1 3 3 3 1 AAA domain VirE PF05272.11 CAR31054.1 - 0.0051 16.6 0.0 1.7 8.4 0.0 3.0 3 0 0 3 3 3 1 Virulence-associated protein E AAA_5 PF07728.14 CAR31054.1 - 0.0071 16.3 0.2 4.3 7.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_27 PF13514.6 CAR31054.1 - 0.014 15.0 0.8 4.1 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 CAR31054.1 - 0.016 15.2 0.2 4.3 7.4 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE G-alpha PF00503.20 CAR31054.1 - 0.019 14.2 0.9 2.9 6.9 0.0 3.2 3 1 1 4 4 4 0 G-protein alpha subunit MeaB PF03308.16 CAR31054.1 - 0.027 13.4 0.0 5.1 6.0 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 CAR31054.1 - 0.029 13.9 0.1 1.9 8.0 0.0 2.5 3 0 0 3 3 2 0 P-loop containing dynein motor region DUF815 PF05673.13 CAR31054.1 - 0.034 13.3 0.0 8.7 5.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 CAR31054.1 - 0.052 13.5 0.1 13 5.6 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Ras PF00071.22 CAR31054.1 - 0.057 13.0 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Ras family PduV-EutP PF10662.9 CAR31054.1 - 0.058 13.1 0.1 28 4.4 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 CAR31054.1 - 0.059 13.2 0.0 12 5.7 0.0 2.7 2 1 0 2 2 2 0 Deoxynucleoside kinase IstB_IS21 PF01695.17 CAR31054.1 - 0.066 12.9 0.0 1.9 8.2 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein FeoB_N PF02421.18 CAR31054.1 - 0.069 12.7 0.0 3.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B NTPase_1 PF03266.15 CAR31054.1 - 0.1 12.5 0.1 2.9 7.8 0.1 2.5 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 CAR31054.1 - 0.12 11.4 0.0 0.61 9.1 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF87 PF01935.17 CAR31054.1 - 0.16 12.0 3.5 31 4.6 0.0 3.9 3 1 1 4 4 4 0 Helicase HerA, central domain AAA_30 PF13604.6 CAR31054.1 - 0.19 11.4 1.3 4.9 6.8 0.1 3.0 3 1 0 3 3 2 0 AAA domain AAA_17 PF13207.6 CAR31054.1 - 0.2 12.1 1.7 25 5.3 0.0 3.3 4 0 0 4 4 2 0 AAA domain CLP1_P PF16575.5 CAR31054.1 - 0.34 10.7 1.8 56 3.5 0.0 3.7 4 0 0 4 4 4 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SH3_7 PF12914.7 CAR31055.1 - 0.18 12.0 0.2 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 SH3 domain of SH3b2 type DUF2779 PF11074.8 CAR31055.1 - 0.61 10.6 3.0 3.9 8.0 3.0 2.3 1 1 0 1 1 1 0 Domain of unknown function(DUF2779) YebO PF13974.6 CAR31055.1 - 2.5 8.2 6.3 0.35 11.0 1.0 2.4 2 1 0 2 2 2 0 YebO-like protein Hydrolase PF00702.26 CAR31056.1 - 1.6e-09 38.4 0.0 3.7e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CAR31056.1 - 1.3e-05 25.4 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase N_formyltrans_C PF18216.1 CAR31056.1 - 0.024 14.3 0.1 0.078 12.7 0.1 1.8 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Nse5 PF08691.10 CAR31057.1 - 2.7e-23 82.4 13.4 7e-23 81.1 13.4 1.7 1 1 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Corazonin PF17308.2 CAR31057.1 - 0.53 10.7 3.5 4.2 7.7 0.0 2.9 2 1 1 3 3 3 0 Pro-corazonin EamA PF00892.20 CAR31058.1 - 6.5e-08 32.8 28.9 0.00065 19.9 9.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF983 PF06170.12 CAR31058.1 - 0.01 16.2 0.9 0.055 13.9 0.9 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF983) TRAP-gamma PF07074.12 CAR31058.1 - 0.027 14.0 0.5 0.095 12.3 0.5 2.0 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) GATA PF00320.27 CAR31059.1 - 5e-14 51.6 6.3 1e-13 50.6 6.3 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CAR31059.1 - 0.086 12.4 0.5 0.19 11.3 0.5 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding XPG_I PF00867.18 CAR31060.1 - 1.5e-23 82.9 0.0 3.4e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CAR31060.1 - 3.6e-05 24.1 0.0 8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CAR31060.1 - 0.0057 16.1 0.1 0.063 12.7 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing A1_Propeptide PF07966.12 CAR31060.1 - 0.51 10.3 3.5 8.7 6.3 0.2 3.2 3 0 0 3 3 3 0 A1 Propeptide PMSR PF01625.21 CAR31061.1 - 3.2e-51 173.5 0.1 3.9e-51 173.2 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase COX4 PF02936.14 CAR31062.1 - 7e-13 48.8 0.1 8.3e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Ost5 PF05251.12 CAR31063.1 - 5.5e-15 55.4 9.5 6.2e-15 55.2 9.5 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Gasdermin_C PF17708.1 CAR31063.1 - 0.038 14.1 0.1 0.048 13.8 0.1 1.2 1 0 0 1 1 1 0 Gasdermin PUB domain Uso1_p115_head PF04869.14 CAR31063.1 - 0.04 13.0 0.1 0.046 12.9 0.1 1.0 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region SPRY PF00622.28 CAR31064.1 - 2.7e-28 98.5 0.3 5.1e-28 97.6 0.3 1.5 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 CAR31064.1 - 7.2e-13 48.7 6.2 4.8e-12 46.0 4.3 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Ubiq_cyt_C_chap PF03981.12 CAR31064.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone CDC45 PF02724.14 CAR31064.1 - 4.7 5.4 18.5 0.015 13.6 8.4 1.7 2 0 0 2 2 2 0 CDC45-like protein AdoHcyase PF05221.17 CAR31065.1 - 1.4e-130 434.8 0.0 3.3e-75 253.0 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CAR31065.1 - 7.4e-85 283.0 2.1 1.2e-84 282.3 2.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CAR31065.1 - 5.8e-07 29.0 0.1 1.1e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CAR31065.1 - 5.7e-05 22.8 0.3 0.00011 21.9 0.3 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CAR31065.1 - 0.0059 16.9 0.1 0.012 15.9 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain DUF2572 PF10833.8 CAR31065.1 - 0.056 13.2 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) Apolipoprotein PF01442.18 CAR31066.1 - 4e-09 36.6 1.9 0.025 14.5 0.0 4.4 4 2 0 4 4 4 2 Apolipoprotein A1/A4/E domain PRANC PF09372.10 CAR31066.1 - 0.026 14.9 2.7 0.05 13.9 0.3 2.7 2 0 0 2 2 2 0 PRANC domain ATP-synt_E_2 PF08112.11 CAR31066.1 - 0.041 14.2 0.6 0.26 11.6 0.0 2.7 3 0 0 3 3 3 0 ATP synthase epsilon subunit CdvA PF18822.1 CAR31066.1 - 0.072 12.9 5.7 0.17 11.7 0.2 3.3 3 1 0 3 3 3 0 CdvA-like coiled-coil domain FlaC_arch PF05377.11 CAR31066.1 - 1.1 9.7 4.0 22 5.5 0.0 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SKA1 PF07160.12 CAR31066.1 - 3.5 7.4 16.6 1.2 8.9 5.0 3.3 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 KxDL PF10241.9 CAR31066.1 - 9.5 6.6 8.9 7 7.0 0.4 4.0 4 0 0 4 4 4 0 Uncharacterized conserved protein SAPS PF04499.15 CAR31067.1 - 5.1e-167 556.6 43.6 2.1e-104 350.1 13.1 3.2 2 2 1 3 3 3 2 SIT4 phosphatase-associated protein DnaJ PF00226.31 CAR31068.1 - 1.9e-14 53.5 1.0 4.4e-14 52.3 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain Adaptin_binding PF10199.9 CAR31070.1 - 0.0017 18.9 4.8 0.07 13.7 0.0 2.6 2 1 1 3 3 3 2 Alpha and gamma adaptin binding protein p34 MgtE_N PF03448.17 CAR31070.1 - 0.012 16.1 0.3 0.03 14.9 0.1 1.7 2 0 0 2 2 2 0 MgtE intracellular N domain Tetraspanin PF00335.20 CAR31071.1 - 0.026 14.2 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family Herpes_UL73 PF03554.13 CAR31071.1 - 0.029 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein DUF1077 PF06417.12 CAR31072.1 - 1.8e-43 147.3 3.9 2.3e-43 146.9 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) THUMP PF02926.17 CAR31073.1 - 1.4e-21 77.1 0.2 3.6e-21 75.8 0.2 1.6 1 0 0 1 1 1 1 THUMP domain Sec15 PF04091.12 CAR31074.1 - 1.2e-107 360.0 9.7 1.2e-107 360.0 9.7 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like Peptidase_M20 PF01546.28 CAR31075.1 - 1.3e-30 106.7 0.0 1.7e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CAR31075.1 - 6.5e-12 45.3 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CAR31075.1 - 0.0094 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Mito_carr PF00153.27 CAR31076.1 - 2.6e-40 136.3 5.4 2.7e-17 62.4 0.2 4.0 3 2 0 3 3 3 3 Mitochondrial carrier protein GARS_A PF01071.19 CAR31077.1 - 1.2e-79 266.6 0.0 2e-79 265.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 CAR31077.1 - 1.7e-32 112.1 0.3 5.4e-32 110.4 0.0 2.0 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 CAR31077.1 - 3e-32 111.9 0.0 7.2e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 CAR31077.1 - 8.2e-29 99.7 0.6 1.9e-28 98.5 0.6 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CAR31077.1 - 2.2e-16 60.3 2.2 1.4e-15 57.7 1.7 2.4 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 CAR31077.1 - 1.2e-05 25.5 0.1 3.1e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 CAR31077.1 - 1.2e-05 24.9 0.0 2.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CAR31077.1 - 0.00014 21.4 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 CAR31077.1 - 0.0027 17.3 0.0 0.0069 16.0 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 CAR31077.1 - 0.022 14.3 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.6 CAR31077.1 - 0.03 13.9 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_ST PF14397.6 CAR31077.1 - 0.09 12.0 0.1 0.56 9.4 0.1 2.0 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp SAD_SRA PF02182.17 CAR31077.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 SAD/SRA domain GIDA PF01134.22 CAR31078.1 - 2.1e-155 517.7 0.0 2.7e-155 517.3 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CAR31078.1 - 4e-70 236.3 0.0 5.8e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 CAR31078.1 - 2.2e-05 23.8 1.6 0.00088 18.6 0.8 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CAR31078.1 - 0.0017 17.8 1.6 0.0029 17.0 1.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CAR31078.1 - 0.012 14.7 1.5 0.03 13.4 1.5 1.6 1 0 0 1 1 1 0 FAD binding domain TraB PF01963.17 CAR31078.1 - 0.064 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 TraB family HI0933_like PF03486.14 CAR31078.1 - 0.68 8.6 2.3 11 4.6 0.6 2.6 3 0 0 3 3 3 0 HI0933-like protein CBFB_NFYA PF02045.15 CAR31080.1 - 2.5e-26 92.1 9.9 7.1e-26 90.6 9.9 1.8 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Cse1 PF08506.10 CAR31081.1 - 5.8e-172 571.6 12.4 9.5e-172 570.9 12.4 1.4 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 CAR31081.1 - 2.9e-108 362.2 3.6 2.9e-108 362.2 3.6 2.2 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 CAR31081.1 - 3.4e-18 65.3 0.0 1.4e-16 60.1 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CAR31081.1 - 0.0023 18.0 2.6 0.037 14.1 0.2 4.0 3 1 0 3 3 3 1 Exportin 1-like protein ANAPC10 PF03256.16 CAR31082.1 - 7.5e-40 136.5 0.0 9.8e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 CAR31082.1 - 0.041 14.0 0.0 0.083 13.0 0.0 1.6 1 1 0 1 1 1 0 F5/8 type C domain QRPTase_C PF01729.19 CAR31083.1 - 6.5e-58 195.2 0.0 8.2e-58 194.9 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 CAR31083.1 - 9.3e-17 60.9 0.0 2.5e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain IBN_N PF03810.19 CAR31084.1 - 8e-10 38.5 0.1 6e-09 35.7 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF4827 PF16109.5 CAR31084.1 - 0.05 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4827) Xpo1 PF08389.12 CAR31084.1 - 0.17 11.9 0.0 0.17 11.9 0.0 5.6 5 2 0 5 5 5 0 Exportin 1-like protein Ank PF00023.30 CAR31085.1 - 1.4e-09 38.0 0.4 0.00079 19.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CAR31085.1 - 7.6e-09 35.1 0.0 0.0002 21.5 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 CAR31085.1 - 3.8e-06 27.4 0.0 8.9e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CAR31085.1 - 2.9e-05 24.2 0.2 0.4 11.1 0.0 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CAR31085.1 - 0.015 15.8 0.4 0.39 11.4 0.0 2.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) A_deamin PF02137.18 CAR31086.1 - 8.6e-30 104.3 0.0 1.1e-29 103.9 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain APOBEC_N PF08210.11 CAR31086.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain Plus-3 PF03126.18 CAR31087.1 - 6.6e-26 91.0 0.0 1.9e-25 89.5 0.0 1.9 1 0 0 1 1 1 1 Plus-3 domain DUF155 PF02582.14 CAR31088.1 - 1.2e-50 172.1 0.1 2.3e-50 171.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 tRNA-synt_1c PF00749.21 CAR31089.1 - 3.9e-115 384.1 0.2 5.3e-115 383.6 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CAR31089.1 - 5.8e-41 140.3 0.5 4.2e-40 137.4 0.1 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 CAR31089.1 - 2.9e-12 46.8 1.1 1.5e-11 44.5 1.1 2.3 1 0 0 1 1 1 1 Glutamate--tRNA ligase N-terminal domain GST_C PF00043.25 CAR31089.1 - 0.00063 19.9 0.0 0.0019 18.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CAR31089.1 - 0.01 15.8 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RAI1 PF08652.11 CAR31090.1 - 2.4e-26 91.7 0.1 4.5e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Aldo_ket_red PF00248.21 CAR31091.1 - 1.2e-41 142.8 0.0 8.6e-41 140.0 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1810 PF08837.11 CAR31091.1 - 0.16 11.8 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1810) Brr6_like_C_C PF10104.9 CAR31092.1 - 4.1e-37 126.9 3.4 4.8e-37 126.7 3.4 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain S36_mt PF10937.8 CAR31093.1 - 1.2e-24 88.1 0.5 1.8e-24 87.5 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial PDEase_II PF02112.15 CAR31094.1 - 1e-55 189.2 0.0 2e-55 188.3 0.0 1.4 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 CAR31094.1 - 0.021 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_L7Ae PF01248.26 CAR31094.1 - 0.23 11.2 0.1 0.44 10.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Proteasome PF00227.26 CAR31095.1 - 9.4e-26 90.5 0.0 1.3e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Clat_adaptor_s PF01217.20 CAR31096.1 - 8.6e-08 32.2 1.1 1.6e-07 31.3 1.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.21 CAR31096.1 - 3.6e-07 29.8 0.2 7.1e-07 28.9 0.2 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family COBRA PF04833.15 CAR31097.1 - 0.046 13.6 0.1 0.092 12.6 0.1 1.4 1 0 0 1 1 1 0 COBRA-like protein DUF2420 PF10336.9 CAR31098.1 - 9.8e-38 128.5 0.3 1.6e-37 127.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Sec63 PF02889.16 CAR31099.1 - 4e-29 101.6 1.0 6.4e-29 100.9 1.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 CAR31099.1 - 9.5e-24 84.1 0.1 4.9e-23 81.8 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CAR31099.1 - 1.5e-10 41.3 0.1 1.3e-09 38.4 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CAR31099.1 - 8.4e-10 38.9 0.0 1.9e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CAR31099.1 - 0.00082 19.7 0.1 0.0065 16.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 CAR31099.1 - 0.046 13.3 0.1 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 CAR31099.1 - 0.062 12.4 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 CAR31099.1 - 0.088 13.1 0.0 0.26 11.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain Ppx-GppA PF02541.16 CAR31100.1 - 8.1e-74 248.6 0.0 1e-73 248.3 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family CSN8_PSD8_EIF3K PF10075.9 CAR31101.1 - 1.7e-21 76.7 0.5 2.6e-21 76.1 0.5 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CAR31101.1 - 9.5e-08 31.8 0.8 1.5e-07 31.1 0.8 1.2 1 0 0 1 1 1 1 SAC3/GANP family Hexokinase_2 PF03727.16 CAR31102.1 - 2e-79 266.4 0.0 2.8e-79 265.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CAR31102.1 - 6.6e-70 235.1 0.0 1e-69 234.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 CAR31102.1 - 0.015 14.8 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain MFS_1 PF07690.16 CAR31103.1 - 6.6e-34 117.4 34.1 6.6e-34 117.4 34.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR31103.1 - 0.00031 19.3 4.0 0.00049 18.6 4.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CAR31104.1 - 3.3e-31 108.5 41.8 3.3e-31 108.5 41.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR31104.1 - 5.7e-05 21.7 5.9 8.8e-05 21.1 5.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Romo1 PF10247.9 CAR31104.1 - 0.05 14.0 3.5 0.23 11.9 0.2 2.9 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 MFS_1 PF07690.16 CAR31105.1 - 1.5e-33 116.2 39.9 1.5e-33 116.2 39.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR31105.1 - 6.4e-05 21.6 5.2 0.0001 20.9 5.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CAR31106.1 - 8.9e-33 113.7 31.7 8.9e-33 113.7 31.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CAR31106.1 - 1.9e-05 23.3 4.7 2.8e-05 22.8 4.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CAR31106.1 - 0.051 11.9 14.5 0.14 10.4 8.1 3.5 1 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Methyltransf_11 PF08241.12 CAR31107.1 - 7e-15 55.5 0.0 1.3e-14 54.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CAR31107.1 - 7e-15 55.5 0.0 1.7e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CAR31107.1 - 8.4e-14 51.6 0.0 1.6e-13 50.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CAR31107.1 - 1.2e-11 45.2 0.0 2.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CAR31107.1 - 4.9e-08 33.0 0.0 7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CAR31107.1 - 7.1e-08 32.1 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 CAR31107.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CAR31107.1 - 0.0063 16.1 0.0 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 CAR31107.1 - 0.0065 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CAR31107.1 - 0.011 15.2 0.0 0.03 13.8 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 CAR31107.1 - 0.021 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 CAR31107.1 - 0.037 13.1 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase MFS_1 PF07690.16 CAR31108.1 - 5.1e-31 107.9 27.4 8e-31 107.2 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2768 PF10966.8 CAR31108.1 - 0.025 15.0 2.1 0.24 11.9 2.1 2.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) DUF4834 PF16118.5 CAR31108.1 - 0.12 13.3 0.9 0.51 11.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) GWT1 PF06423.12 CAR31108.1 - 0.14 12.3 0.4 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 GWT1 DUF202 PF02656.15 CAR31108.1 - 0.15 12.5 11.0 1.1e+02 3.4 7.3 4.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) MFS_1 PF07690.16 CAR31109.1 - 2e-14 53.3 25.3 2e-14 53.3 25.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.6 CAR31109.1 - 0.23 11.1 0.1 0.23 11.1 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Herpes_UL92 PF03048.14 CAR31109.1 - 0.27 11.0 1.7 0.82 9.4 0.4 2.1 2 0 0 2 2 2 0 UL92 family MFS_1 PF07690.16 CAR31110.1 - 8.5e-35 120.3 18.9 7e-34 117.3 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CAR31110.1 - 9.6e-10 37.9 4.9 1.8e-09 37.0 4.9 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CAR31110.1 - 0.00083 17.9 0.4 0.0014 17.2 0.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2754 PF10953.8 CAR31110.1 - 1.3 9.3 0.0 1.3 9.3 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2754) Catalase PF00199.19 CAR31113.1 - 3.7e-182 605.6 0.0 4.7e-182 605.3 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CAR31113.1 - 3.3e-09 36.8 0.0 8.4e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive PPV_E2_C PF00511.17 CAR31113.1 - 0.21 11.8 0.4 2.2 8.5 0.1 2.3 2 0 0 2 2 2 0 E2 (early) protein, C terminal GMC_oxred_N PF00732.19 CAR31114.1 - 4e-39 134.8 0.0 5.1e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CAR31114.1 - 2.6e-33 115.6 0.0 3.9e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Epimerase PF01370.21 CAR31115.1 - 6.1e-22 78.2 0.0 9.4e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CAR31115.1 - 3.5e-14 52.9 0.0 6.1e-14 52.2 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CAR31115.1 - 6.6e-14 51.7 0.0 4.5e-08 32.6 0.0 2.6 2 1 1 3 3 3 2 Male sterility protein 3Beta_HSD PF01073.19 CAR31115.1 - 2.1e-13 49.9 0.0 3.1e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CAR31115.1 - 2.3e-08 34.1 0.0 3.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CAR31115.1 - 5.6e-07 29.0 0.0 3.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 CAR31115.1 - 1.5e-06 27.8 0.0 3.7e-05 23.3 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 CAR31115.1 - 0.0007 19.2 0.0 0.004 16.7 0.1 2.2 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 CAR31115.1 - 0.006 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CAR31115.1 - 0.062 12.4 0.0 0.11 11.5 0.0 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain Flavoprotein PF02441.19 CAR31116.1 - 2.1e-23 82.8 0.1 2.7e-23 82.5 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein UbiD PF01977.16 CAR31117.1 - 8.4e-109 364.1 0.0 9.6e-109 363.9 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Sortilin-Vps10 PF15902.5 CAR31118.1 - 1.8e-53 181.9 0.1 2.9e-27 95.6 0.1 2.9 2 1 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CAR31118.1 - 2.5e-14 54.0 0.1 4.9e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CAR31118.1 - 1.5e-05 24.3 28.5 1.8 8.9 0.2 8.5 9 0 0 9 9 9 4 BNR/Asp-box repeat PSII_BNR PF14870.6 CAR31118.1 - 0.0057 16.0 0.7 0.055 12.7 0.1 2.6 3 0 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 CHB_HEX_C PF03174.13 CAR31118.1 - 0.35 10.9 0.8 61 3.7 0.0 4.1 4 0 0 4 4 4 0 Chitobiase/beta-hexosaminidase C-terminal domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Zygosaccharomyces_rouxii-ASM2636v1/GCA_000026365.1_ASM2636v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Zygosaccharomyces_rouxii-ASM2636v1/GCA_000026365.1_ASM2636v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Zygosaccharomyces_rouxii-ASM2636v1/GCA_000026365.1_ASM2636v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Zygosaccharomyces_rouxii-ASM2636v1/GCA_000026365.1_ASM2636v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 07:53:30 2019 # [ok]