# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Hexapep PF00132.19 EDO14288.1 - 3.5e-08 32.5 4.4 1e-05 24.7 1.1 3.8 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EDO14288.1 - 0.38 10.3 5.5 8.9 5.9 2.7 3.4 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase GN3L_Grn1 PF08701.6 EDO14289.1 - 2.2e-25 88.3 15.9 4.7e-25 87.2 11.0 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EDO14289.1 - 0.0014 18.5 0.1 0.0036 17.2 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDO14289.1 - 0.011 15.1 0.3 0.026 13.9 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EDO14289.1 - 0.1 12.3 3.2 0.29 10.9 2.2 2.1 1 1 0 1 1 1 0 Dynamin family MRI PF15325.1 EDO14289.1 - 1.4 9.9 5.0 0.23 12.4 0.6 1.8 2 0 0 2 2 2 0 Modulator of retrovirus infection Flocculin PF00624.13 EDO14290.1 - 1.8e-191 619.8 436.5 5.7e-15 54.8 17.9 13.6 14 0 0 14 14 14 13 Flocculin repeat PDR_assoc PF08370.6 EDO14290.1 - 3.1e-15 55.4 21.9 27 4.3 0.0 13.1 13 0 0 13 13 13 13 Plant PDR ABC transporter associated Lumazine_bd PF12870.2 EDO14290.1 - 0.0068 16.4 38.0 1.2e+02 2.8 0.0 12.2 13 0 0 13 13 13 0 Lumazine-binding domain RVT_1 PF00078.22 EDO14291.1 - 3.1e-17 62.6 0.1 3.7e-15 55.8 0.1 2.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Use1 PF09753.4 EDO14291.1 - 3.1 7.1 26.8 0.62 9.4 8.3 3.5 2 1 2 4 4 4 0 Membrane fusion protein Use1 PLRV_ORF5 PF01690.12 EDO14291.1 - 5.9 5.9 9.9 8.2 5.4 6.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Phage_capsid PF05065.8 EDO14292.1 - 0.041 13.0 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Phage capsid family Lge1 PF11488.3 EDO14293.1 - 3.4e-17 62.4 3.3 3.4e-17 62.4 2.3 2.3 2 1 1 3 3 3 1 Transcriptional regulatory protein LGE1 CAP_N PF01213.14 EDO14293.1 - 0.096 11.9 3.3 0.19 11.0 2.3 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal BAF1_ABF1 PF04684.8 EDO14293.1 - 0.2 10.4 30.2 0.31 9.8 20.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor COX14 PF14880.1 EDO14293.1 - 0.47 10.1 3.8 1.1 8.9 2.6 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c assembly FCP1_C PF09309.5 EDO14293.1 - 0.73 9.0 7.6 0.3 10.3 3.4 1.7 2 0 0 2 2 2 0 FCP1, C-terminal APC_CDC26 PF10471.4 EDO14293.1 - 1.4 9.6 14.9 6.3 7.6 10.3 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Activator_LAG-3 PF11498.3 EDO14293.1 - 1.7 7.2 27.8 2.6 6.6 19.3 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med3 PF11593.3 EDO14293.1 - 2.2 7.4 15.6 6.5 5.8 10.8 1.9 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PHD_3 PF13922.1 EDO14293.1 - 6.4 7.0 10.3 18 5.6 7.1 1.9 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Spt5_N PF11942.3 EDO14293.1 - 7 7.3 13.7 0.49 11.0 5.3 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal KcnmB2_inactiv PF09303.5 EDO14295.1 - 0.033 13.9 0.5 0.16 11.7 0.3 2.2 1 0 0 1 1 1 0 KCNMB2, ball and chain domain RAP1 PF07218.6 EDO14295.1 - 7 4.6 16.1 8.3 4.3 11.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PS_Dcarbxylase PF02666.10 EDO14296.1 - 3.9e-72 241.7 0.0 4.9e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Glyco_trans_4_4 PF13579.1 EDO14299.1 - 0.0067 16.5 0.1 0.0098 16.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain PTB PF08416.8 EDO14300.1 - 0.13 12.1 0.1 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotyrosine-binding domain PTB PF08416.8 EDO14302.1 - 0.12 12.2 0.1 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotyrosine-binding domain SF3a60_bindingd PF12108.3 EDO14303.1 - 0.029 13.9 0.0 0.078 12.5 0.0 1.8 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Methyltransf_16 PF10294.4 EDO14306.1 - 5.6e-07 29.1 0.5 0.021 14.2 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase Semialdhyde_dhC PF02774.13 EDO14307.1 - 7.3e-44 149.8 0.0 9.6e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EDO14307.1 - 3.5e-29 101.5 0.0 6e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EDO14307.1 - 0.013 15.3 0.0 0.033 14.1 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EDO14307.1 - 0.03 14.8 0.0 0.087 13.3 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RRM_1 PF00076.17 EDO14308.1 - 3.3e-19 68.2 0.2 1.1e-18 66.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO14308.1 - 8.6e-11 41.6 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO14308.1 - 1.7e-07 30.9 0.0 3.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.14 EDO14309.1 - 0.00017 21.4 1.6 0.00018 21.3 1.1 1.2 1 0 0 1 1 1 1 SPX domain rRNA_processing PF08524.6 EDO14309.1 - 0.34 10.7 13.4 0.58 9.9 9.3 1.3 1 0 0 1 1 1 0 rRNA processing TFIIF_alpha PF05793.7 EDO14309.1 - 1.5 7.0 14.1 2 6.7 9.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bromodomain PF00439.20 EDO14310.1 - 5.7e-30 103.0 5.3 4.9e-19 68.0 0.2 2.4 2 0 0 2 2 2 2 Bromodomain DUF3023 PF11224.3 EDO14310.1 - 0.068 12.8 1.0 0.16 11.6 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3023) Urm1 PF09138.6 EDO14310.1 - 2.9 8.0 6.0 2.2 8.4 0.5 2.5 1 1 1 2 2 2 0 Urm1 (Ubiquitin related modifier) LAMTOR PF15454.1 EDO14311.1 - 3.5e-09 36.8 3.0 5.9e-09 36.0 2.1 1.4 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Ribosomal_L50 PF10501.4 EDO14312.1 - 3.7e-25 88.0 0.7 3.7e-25 88.0 0.5 1.8 2 0 0 2 2 2 1 Ribosomal subunit 39S Glyco_transf_15 PF01793.11 EDO14313.1 - 2.7e-132 440.7 20.6 3.5e-132 440.3 14.3 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase zf-CCCH PF00642.19 EDO14314.1 - 1.7e-09 37.1 12.8 7.9e-05 22.2 2.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EDO14314.1 - 0.011 15.6 19.5 0.19 11.7 5.1 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF605 PF04652.11 EDO14314.1 - 0.51 9.6 10.7 0.76 9.1 7.4 1.3 1 0 0 1 1 1 0 Vta1 like RNA_pol_Rpb1_5 PF04998.12 EDO14315.1 - 4.7e-107 357.3 0.2 7.9e-107 356.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EDO14315.1 - 1.8e-73 245.9 0.1 7.1e-73 244.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EDO14315.1 - 6e-64 215.2 0.6 6e-64 215.2 0.4 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EDO14315.1 - 1.2e-47 161.5 0.0 3.3e-47 160.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EDO14315.1 - 6.2e-45 152.2 3.0 1.6e-44 150.8 2.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EDO14315.1 - 6.3e-36 122.4 0.1 2e-35 120.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 EDO14315.1 - 5e-06 25.9 1.6 1.1e-05 24.8 1.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 DUF4123 PF13503.1 EDO14315.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) gag_pre-integrs PF13976.1 EDO14316.1 - 1e-14 53.8 0.4 2.8e-13 49.2 0.0 2.7 2 0 0 2 2 2 1 GAG-pre-integrase domain eIF3g PF12353.3 EDO14316.1 - 0.055 13.3 5.5 0.14 12.1 3.2 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G RVP PF00077.15 EDO14316.1 - 0.061 13.2 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF4101 PF13355.1 EDO14316.1 - 0.088 13.2 1.0 0.45 10.9 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4101) Ribosomal_S5 PF00333.15 EDO14317.1 - 2.7e-24 84.6 0.1 4.5e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EDO14317.1 - 9.9e-17 59.9 0.0 2.1e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Tctex-1 PF03645.8 EDO14318.1 - 2.2e-07 30.6 0.1 2.9e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 EDO14319.1 - 6.5e-14 51.8 1.9 6.5e-14 51.8 1.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LHC PF00556.15 EDO14319.1 - 0.0083 15.9 0.4 0.023 14.5 0.3 1.7 1 0 0 1 1 1 1 Antenna complex alpha/beta subunit DUF4234 PF14018.1 EDO14319.1 - 0.12 12.1 0.2 0.18 11.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) DUF2207 PF09972.4 EDO14319.1 - 1.3 7.5 5.2 0.5 8.8 0.6 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Y_phosphatase PF00102.22 EDO14320.1 - 1e-47 162.5 0.4 2e-47 161.5 0.3 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EDO14320.1 - 1.1e-09 38.6 0.0 6.4e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EDO14320.1 - 0.073 13.3 0.1 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family DSPc PF00782.15 EDO14320.1 - 0.12 11.9 0.1 0.12 11.9 0.0 2.8 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain DEAD PF00270.24 EDO14321.1 - 3.2e-45 153.6 0.0 7e-44 149.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO14321.1 - 1.1e-10 41.2 0.0 2.5e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO14321.1 - 0.00026 20.8 0.0 0.00091 19.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EDO14321.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_19 PF13245.1 EDO14321.1 - 0.082 12.6 0.0 19 5.0 0.0 2.7 2 1 0 2 2 2 0 Part of AAA domain RNA_pol_L_2 PF13656.1 EDO14322.1 - 1.7e-31 107.4 0.0 2.5e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EDO14322.1 - 7.2e-13 47.4 0.0 9.9e-13 47.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.20 EDO14323.1 - 1.3e-58 198.2 0.0 1.5e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO14323.1 - 2e-30 105.7 0.0 2.6e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO14323.1 - 1.1e-05 24.5 0.0 2.5e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDO14323.1 - 0.0015 18.3 0.0 0.0033 17.1 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDO14323.1 - 0.019 14.0 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EDO14323.1 - 0.038 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Nucleopor_Nup85 PF07575.8 EDO14326.1 - 3.6e-183 609.8 11.6 4.3e-183 609.5 8.0 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin ATP-synt_C PF00137.16 EDO14327.1 - 4.1e-32 109.8 28.6 8.9e-19 67.1 7.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EDO14327.1 - 0.91 9.0 4.5 0.26 10.8 0.9 1.6 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A zf-DNL PF05180.7 EDO14328.1 - 1.5e-31 107.9 2.2 3.1e-31 106.9 1.6 1.5 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 EDO14328.1 - 0.0047 16.6 2.3 0.0075 15.9 1.6 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Cyclase_polyket PF04673.7 EDO14328.1 - 0.062 13.3 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Polyketide synthesis cyclase zf-CSL PF05207.8 EDO14328.1 - 0.098 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 CSL zinc finger zinc_ribbon_4 PF13717.1 EDO14328.1 - 1.1 9.0 4.3 4.9 6.9 3.0 2.0 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EDO14328.1 - 1.4 8.5 4.3 7.4 6.2 3.1 2.1 1 1 1 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 EDO14328.1 - 2.2 7.9 4.8 22 4.7 0.4 2.1 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) F-box-like PF12937.2 EDO14329.1 - 1.8e-07 30.7 0.6 5.5e-07 29.2 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO14329.1 - 7.4e-07 28.6 1.9 7.4e-07 28.6 1.3 2.4 2 0 0 2 2 2 1 F-box domain tRNA_anti-codon PF01336.20 EDO14330.1 - 8.3e-13 47.9 0.2 1.4e-12 47.2 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 EDO14330.1 - 1.2e-07 32.0 0.4 5.2e-07 30.0 0.0 2.2 2 1 1 3 3 3 1 Replication protein A C terminal HTH_IclR PF09339.5 EDO14330.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain NlpE PF04170.7 EDO14333.1 - 0.031 14.6 0.9 1.2 9.6 0.1 2.5 2 1 0 2 2 2 0 NlpE N-terminal domain Asparaginase PF00710.15 EDO14336.1 - 6.6e-22 77.7 0.0 1.2e-21 76.8 0.0 1.4 1 1 0 1 1 1 1 Asparaginase TPR_1 PF00515.23 EDO14337.1 - 6.1e-50 164.8 22.5 6.4e-08 31.8 0.0 11.1 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_11 PF13414.1 EDO14337.1 - 8e-46 153.5 35.3 3.2e-10 39.4 1.7 6.6 2 2 4 7 7 7 7 TPR repeat TPR_2 PF07719.12 EDO14337.1 - 1.4e-45 149.5 24.6 3.3e-05 23.4 0.0 10.5 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 EDO14337.1 - 3.4e-33 111.0 25.2 0.00014 21.8 0.0 10.5 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 EDO14337.1 - 6.8e-31 106.0 33.7 3e-08 33.4 0.3 7.9 3 2 4 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 EDO14337.1 - 3.9e-29 100.6 16.3 2.7e-06 27.8 0.4 6.6 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 EDO14337.1 - 2.8e-27 92.3 17.6 0.019 14.7 0.1 10.3 9 2 1 10 10 10 8 Tetratricopeptide repeat TPR_14 PF13428.1 EDO14337.1 - 1.2e-26 90.7 20.0 5e-05 23.5 0.1 10.1 2 2 8 10 10 10 8 Tetratricopeptide repeat TPR_7 PF13176.1 EDO14337.1 - 8.9e-24 81.3 24.2 9.1e-05 21.9 0.1 10.1 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 EDO14337.1 - 2.6e-19 69.2 14.3 6.6e-06 26.3 0.3 6.8 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_9 PF13371.1 EDO14337.1 - 2.5e-18 65.6 8.8 5.5e-06 26.1 0.0 6.0 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_6 PF13174.1 EDO14337.1 - 1.6e-14 53.2 28.1 0.22 12.0 0.0 9.7 9 1 0 9 9 8 4 Tetratricopeptide repeat Apc3 PF12895.2 EDO14337.1 - 2e-13 50.2 11.2 0.00011 22.3 0.1 4.3 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EDO14337.1 - 1.2e-09 37.6 16.4 0.0018 17.3 0.2 4.7 1 1 4 5 5 5 5 Tetratricopeptide repeat RPN7 PF10602.4 EDO14337.1 - 4.9e-05 22.7 3.7 1.7 8.0 0.0 5.0 3 3 1 5 5 5 1 26S proteasome subunit RPN7 TPR_10 PF13374.1 EDO14337.1 - 0.00018 21.2 22.7 0.11 12.4 0.5 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat Imm43 PF15602.1 EDO14337.1 - 0.00034 20.6 0.0 0.11 12.4 0.0 3.6 3 1 1 4 4 4 1 Immunity protein 43 MIT PF04212.13 EDO14337.1 - 0.00062 19.5 6.8 1.6 8.6 0.0 5.3 6 2 0 6 6 4 1 MIT (microtubule interacting and transport) domain ChAPs PF09295.5 EDO14337.1 - 0.0014 17.5 3.4 0.12 11.1 0.5 3.2 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.1 EDO14337.1 - 0.003 16.7 17.6 0.62 9.1 3.7 4.7 4 2 1 5 5 4 2 Soluble NSF attachment protein, SNAP NARP1 PF12569.3 EDO14337.1 - 0.057 12.1 13.5 1.6 7.4 0.0 4.2 4 1 0 5 5 5 0 NMDA receptor-regulated protein 1 AAA_16 PF13191.1 EDO14337.1 - 0.17 11.8 1.9 0.4 10.6 1.3 1.6 1 0 0 1 1 1 0 AAA ATPase domain eIF_4EBP PF05456.6 EDO14337.1 - 0.56 9.9 4.2 1.1 8.9 2.9 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) TPR_20 PF14561.1 EDO14337.1 - 1.9 8.6 0.0 1.9 8.6 0.0 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat ABC_membrane PF00664.18 EDO14338.1 - 4.3e-32 111.6 54.5 2.9e-17 62.9 13.0 3.7 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDO14338.1 - 1.7e-22 80.2 0.8 3.7e-19 69.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_23 PF13476.1 EDO14338.1 - 0.00051 20.4 2.3 0.00052 20.3 0.2 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDO14338.1 - 0.0062 15.7 0.1 0.015 14.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 EDO14338.1 - 0.05 12.5 0.5 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EDO14338.1 - 0.16 11.0 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SMC_N PF02463.14 EDO14338.1 - 0.25 10.5 0.4 3.7 6.7 0.1 2.3 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EDO14338.1 - 0.35 10.2 0.0 0.73 9.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.17 EDO14339.1 - 1.3e-18 66.3 5.7 7e-10 38.4 0.4 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO14339.1 - 1.7e-12 47.1 0.7 6.7e-06 25.9 0.1 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO14339.1 - 0.0011 18.7 0.1 1.8 8.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Gly-rich_Ago1 PF12764.2 EDO14339.1 - 0.021 15.4 5.1 0.044 14.4 3.6 1.5 1 0 0 1 1 1 0 Glycine-rich region of argonaut HTH_Tnp_IS630 PF01710.11 EDO14339.1 - 0.48 10.1 0.0 0.48 10.1 0.0 2.3 3 0 0 3 3 3 0 Transposase dUTPase PF00692.14 EDO14343.1 - 8.2e-43 144.9 0.0 9.6e-43 144.7 0.0 1.1 1 0 0 1 1 1 1 dUTPase FtsZ_C PF12327.3 EDO14343.1 - 0.088 12.8 0.1 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 FtsZ family, C-terminal domain Sedlin_N PF04628.8 EDO14344.1 - 1.3e-46 157.7 0.0 1.6e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EDO14344.1 - 3.5e-08 33.2 0.1 5.7e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family Adeno_E1A PF02703.9 EDO14345.1 - 0.022 14.1 0.6 0.022 14.1 0.4 1.9 2 0 0 2 2 2 0 Early E1A protein DUF3169 PF11368.3 EDO14346.1 - 0.073 12.2 0.0 0.086 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Guanylate_cyc_2 PF09778.4 EDO14346.1 - 0.13 11.4 0.2 0.17 11.0 0.1 1.4 1 1 0 1 1 1 0 Guanylylate cyclase Opy2 PF09463.5 EDO14347.1 - 4e-11 42.7 20.3 6e-11 42.2 14.1 1.3 1 0 0 1 1 1 1 Opy2 protein S1FA PF04689.8 EDO14347.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA binding protein S1FA Zn_Tnp_IS1595 PF12760.2 EDO14347.1 - 4 7.3 6.3 7 6.5 4.4 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain tRNA-synt_1b PF00579.20 EDO14348.1 - 1.2e-54 185.4 0.0 1.6e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PrgI PF12666.2 EDO14349.1 - 0.048 13.8 0.7 0.053 13.6 0.5 1.1 1 0 0 1 1 1 0 PrgI family protein RDD PF06271.7 EDO14349.1 - 0.73 9.7 4.0 0.87 9.4 2.7 1.1 1 0 0 1 1 1 0 RDD family Transglut_core PF01841.14 EDO14350.1 - 1.1e-11 44.9 0.0 2.3e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 EDO14350.1 - 7.8e-10 38.3 5.6 6.2e-09 35.3 3.9 2.3 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain Desulfoferrod_N PF06397.7 EDO14350.1 - 0.0056 16.0 1.2 0.0056 16.0 0.8 1.9 2 0 0 2 2 2 1 Desulfoferrodoxin, N-terminal domain Zn_Tnp_IS1595 PF12760.2 EDO14350.1 - 0.094 12.5 4.4 0.77 9.6 3.0 2.3 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DEK_C PF08766.6 EDO14351.1 - 0.23 11.2 3.7 0.43 10.3 1.5 2.2 1 1 1 2 2 2 0 DEK C terminal domain Dynamin_N PF00350.18 EDO14352.1 - 8.1e-08 32.2 0.2 4.7e-07 29.7 0.0 2.2 2 1 0 2 2 2 1 Dynamin family Miro PF08477.8 EDO14352.1 - 0.0038 17.7 0.1 0.84 10.1 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EDO14352.1 - 0.0081 16.1 0.0 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase PPV_E1_C PF00519.12 EDO14352.1 - 0.037 12.6 0.3 0.12 10.9 0.0 1.7 2 0 0 2 2 2 0 Papillomavirus helicase Glucan_synthase PF02364.10 EDO14354.1 - 3.3e-155 518.1 8.4 4.2e-155 517.8 5.8 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component UxuA PF03786.8 EDO14354.1 - 0.06 11.8 0.1 0.092 11.2 0.0 1.2 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) Glyco_hydro_72 PF03198.9 EDO14355.1 - 3.4e-137 456.6 1.6 4.6e-137 456.1 1.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EDO14355.1 - 5.1e-17 62.1 1.5 1.4e-16 60.7 1.0 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_17 PF00332.13 EDO14355.1 - 0.0033 16.4 0.1 0.0078 15.2 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Pkinase PF00069.20 EDO14356.1 - 4.4e-70 235.8 0.0 8.8e-70 234.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO14356.1 - 5.1e-30 104.4 0.0 7e-29 100.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO14356.1 - 8.5e-08 31.4 0.1 2.5e-06 26.6 0.0 2.4 2 1 0 2 2 2 1 Kinase-like MCR_beta PF02241.13 EDO14356.1 - 0.01 15.1 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 1 Methyl-coenzyme M reductase beta subunit, C-terminal domain Kdo PF06293.9 EDO14356.1 - 0.075 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO14356.1 - 0.095 12.4 0.0 7.6 6.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family MutS_V PF00488.16 EDO14357.1 - 2.5e-73 246.3 0.0 1e-72 244.3 0.0 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EDO14357.1 - 7.6e-37 127.0 0.2 1.8e-36 125.8 0.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EDO14357.1 - 6.3e-29 100.2 0.1 1.3e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 EDO14357.1 - 1.5e-10 41.1 1.3 6.8e-10 38.9 0.9 2.2 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EDO14357.1 - 1.3e-05 25.2 1.9 3.2e-05 23.9 0.2 2.6 2 1 1 3 3 3 1 MutS domain II AMPKBI PF04739.10 EDO14358.1 - 6.5e-33 112.6 3.6 6.5e-33 112.6 2.5 3.1 3 1 1 4 4 4 1 5'-AMP-activated protein kinase beta subunit, interation domain GAGA_bind PF06217.7 EDO14358.1 - 3 7.7 18.2 0.95 9.3 2.7 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Pneumo_phosprot PF02478.11 EDO14358.1 - 5.1 6.5 13.2 1 8.8 1.8 2.3 2 0 0 2 2 2 0 Pneumovirus phosphoprotein EBV-NA3 PF05009.7 EDO14359.1 - 0.052 12.7 1.1 0.15 11.2 0.8 1.8 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) SKN1 PF03935.10 EDO14360.1 - 6.9e-254 842.6 6.8 9e-254 842.2 4.7 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF4137 PF13593.1 EDO14361.1 - 2.7e-115 384.7 17.6 3.2e-115 384.5 12.2 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EDO14361.1 - 8.5e-11 41.6 7.9 8.5e-11 41.6 5.5 1.6 1 1 0 1 1 1 1 Sodium Bile acid symporter family Actin PF00022.14 EDO14362.1 - 8.6e-20 70.5 0.0 2e-17 62.6 0.0 2.7 1 1 1 2 2 2 2 Actin FtsA PF14450.1 EDO14362.1 - 0.012 15.3 0.1 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Cell division protein FtsA Histone PF00125.19 EDO14363.1 - 8.7e-26 89.8 0.8 1.7e-25 88.9 0.6 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDO14363.1 - 0.0085 16.2 0.1 0.016 15.3 0.1 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S MFS_1 PF07690.11 EDO14365.1 - 2.8e-19 69.0 24.5 3.9e-19 68.5 17.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF389 PF04087.9 EDO14365.1 - 0.84 9.5 9.9 1.2 9.0 0.1 4.2 4 1 2 6 6 6 0 Domain of unknown function (DUF389) SecY PF00344.15 EDO14366.1 - 4.3e-89 298.8 13.2 5.5e-89 298.4 9.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EDO14366.1 - 1.1e-17 63.1 0.2 1.1e-17 63.1 0.1 2.8 3 0 0 3 3 3 1 Plug domain of Sec61p Claudin_3 PF06653.6 EDO14366.1 - 0.18 11.5 4.2 1 9.0 0.0 2.8 3 0 0 3 3 3 0 Tight junction protein, Claudin-like RNA_binding PF01877.12 EDO14367.1 - 0.47 10.4 5.2 0.12 12.3 0.7 2.2 2 1 0 2 2 2 0 RNA binding CBF PF03914.12 EDO14368.1 - 9.4e-37 125.9 0.1 9.4e-37 125.9 0.1 2.4 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 EDO14368.1 - 9.3e-35 118.7 0.6 9.3e-35 118.7 0.4 2.8 2 1 0 2 2 2 1 Nucleolar complex-associated protein CENP-T PF15511.1 EDO14368.1 - 0.012 14.9 10.2 0.013 14.7 5.3 1.9 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Sigma70_ner PF04546.8 EDO14368.1 - 0.11 12.0 20.1 1.5 8.3 8.4 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region NARP1 PF12569.3 EDO14368.1 - 0.13 10.9 23.2 0.3 9.7 3.3 2.7 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 Peptidase_A3 PF02160.10 EDO14368.1 - 1 8.9 12.9 5.2 6.6 4.3 2.4 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) CDC45 PF02724.9 EDO14368.1 - 1.3 6.9 15.9 0.026 12.5 4.9 2.0 2 0 0 2 2 2 0 CDC45-like protein LMBR1 PF04791.11 EDO14368.1 - 2.3 6.6 9.6 0.066 11.7 1.8 1.9 2 0 0 2 2 2 0 LMBR1-like membrane protein RVT_2 PF07727.9 EDO14370.1 - 1.7e-78 263.0 0.0 2.5e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO14370.1 - 7.5e-24 84.1 0.5 2.5e-23 82.4 0.2 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EDO14370.1 - 0.023 14.1 0.0 0.15 11.5 0.0 2.3 2 0 0 2 2 2 0 Integrase core domain Glyco_trans_4_4 PF13579.1 EDO14370.1 - 0.074 13.1 0.1 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain PTB PF08416.8 EDO14371.1 - 0.09 12.6 0.2 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotyrosine-binding domain RseA_C PF03873.8 EDO14372.1 - 2.3 8.1 18.9 1.8 8.4 0.4 6.1 2 2 4 6 6 6 0 Anti sigma-E protein RseA, C-terminal domain Pox_A21 PF05323.7 EDO14375.1 - 0.15 12.4 6.8 5.1e+03 -2.2 0.0 10.4 2 2 3 13 13 13 0 Poxvirus A21 Protein DUF1353 PF07087.6 EDO14377.1 - 5.1e-33 112.4 138.0 22 4.6 0.0 51.4 1 1 53 54 54 54 41 Protein of unknown function (DUF1353) DUF1659 PF07872.6 EDO14377.1 - 0.63 9.7 61.6 5.6e+02 0.2 0.0 25.7 32 0 0 32 32 32 0 Protein of unknown function (DUF1659) Ribosomal_L23 PF00276.15 EDO14379.1 - 3.6e-20 71.7 0.0 6.3e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 RNA_pol_Rpb2_6 PF00562.23 EDO14380.1 - 1.3e-126 422.5 0.1 2.6e-126 421.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDO14380.1 - 3.1e-72 241.7 0.1 4.9e-72 241.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EDO14380.1 - 5.8e-52 175.8 0.0 1.1e-51 174.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EDO14380.1 - 3.9e-30 103.9 0.1 1e-29 102.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EDO14380.1 - 8.3e-29 99.1 2.0 1.4e-28 98.4 0.4 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EDO14380.1 - 5.6e-22 77.2 0.1 1.8e-21 75.6 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EDO14380.1 - 2.6e-18 65.7 3.8 8.2e-18 64.1 2.6 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 SHS2_Rpb7-N PF03876.12 EDO14381.1 - 7.9e-17 61.1 0.0 1.5e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EDO14381.1 - 1.3e-15 57.2 0.1 1.8e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EDO14381.1 - 5.6e-06 26.5 0.0 1.1e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 IIGP PF05049.8 EDO14384.1 - 0.02 13.6 0.2 0.026 13.3 0.1 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) APG6 PF04111.7 EDO14384.1 - 0.39 9.7 5.6 0.58 9.1 3.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 KxDL PF10241.4 EDO14384.1 - 0.63 9.9 3.5 0.66 9.9 0.3 2.5 2 1 0 3 3 3 0 Uncharacterized conserved protein zf-C3HC4_3 PF13920.1 EDO14385.1 - 3.5e-07 29.7 13.2 6e-07 29.0 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO14385.1 - 9.4 6.3 17.0 21 5.2 11.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AICARFT_IMPCHas PF01808.13 EDO14386.1 - 2.2e-115 385.0 0.0 3.2e-115 384.5 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EDO14386.1 - 1.8e-25 88.6 0.0 3.5e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain RRM_1 PF00076.17 EDO14387.1 - 5e-33 112.5 0.0 1.8e-15 56.2 0.1 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO14387.1 - 1.2e-29 102.0 0.0 3e-12 46.3 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO14387.1 - 7.3e-14 51.3 0.1 2.8e-07 30.2 0.0 4.6 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 EDO14387.1 - 0.002 16.2 6.9 0.002 16.2 4.8 2.5 3 0 0 3 3 3 1 CDC45-like protein FLILHELTA PF10306.4 EDO14388.1 - 1.6e-25 88.9 0.1 4.6e-25 87.4 0.1 1.7 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA ApbA_C PF08546.6 EDO14389.1 - 1.8e-06 27.9 0.0 1.6e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DJ-1_PfpI PF01965.19 EDO14391.1 - 3.5e-21 75.1 0.0 7.5e-21 74.1 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EDO14391.1 - 2.7e-05 23.6 0.1 7.3e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family KAR9 PF08580.5 EDO14393.1 - 1.7e-88 297.6 40.1 4.8e-88 296.1 27.8 1.7 1 1 0 1 1 1 1 Yeast cortical protein KAR9 Herpes_BLRF2 PF05812.7 EDO14393.1 - 0.19 11.5 6.1 0.99 9.2 0.4 2.7 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Phasin PF05597.6 EDO14393.1 - 0.42 10.3 3.6 2.6 7.8 0.2 2.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tropomyosin_1 PF12718.2 EDO14393.1 - 2.9 7.7 15.1 13 5.6 2.5 2.9 1 1 1 2 2 2 0 Tropomyosin like DUF904 PF06005.7 EDO14393.1 - 4.2 7.7 17.2 4.7 7.5 0.0 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF904) Syntaxin PF00804.20 EDO14393.1 - 6.2 7.0 16.2 3 8.0 0.8 4.1 2 2 0 3 3 3 0 Syntaxin Daxx PF03344.10 EDO14395.1 - 0.062 11.7 14.4 0.091 11.2 10.0 1.1 1 0 0 1 1 1 0 Daxx Family DEAD_2 PF06733.10 EDO14396.1 - 1.7e-50 170.8 0.9 3.4e-50 169.8 0.6 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EDO14396.1 - 9.8e-48 162.2 0.0 5.6e-47 159.8 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 EDO14396.1 - 0.00072 19.0 0.4 0.49 9.8 0.0 2.6 2 1 0 2 2 2 2 DEAD/DEAH box helicase PhoH PF02562.11 EDO14396.1 - 0.013 14.7 0.3 1.5 7.9 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 EDO14396.1 - 0.014 15.5 2.8 0.89 9.7 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDO14396.1 - 0.13 12.0 0.0 0.87 9.3 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 EDO14396.1 - 0.23 11.2 11.7 0.44 10.3 0.0 4.0 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit Folate_rec PF03024.9 EDO14397.1 - 0.00057 19.5 2.8 0.00086 18.9 1.9 1.3 1 0 0 1 1 1 1 Folate receptor family Chitin_bind_1 PF00187.14 EDO14397.1 - 1.7 8.6 9.9 1.3 9.0 1.0 2.9 3 0 0 3 3 3 0 Chitin recognition protein Rhodanese PF00581.15 EDO14398.1 - 7.8e-12 45.5 0.0 1.9e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DUF262 PF03235.9 EDO14398.1 - 0.11 12.4 3.8 1.1 9.1 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF262 Borrelia_orfD PF02999.9 EDO14398.1 - 5 7.3 7.1 3.9 7.6 0.2 3.3 2 1 1 3 3 3 0 Borrelia orf-D family Pkinase PF00069.20 EDO14399.1 - 2.3e-43 148.2 0.1 1.2e-42 145.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO14399.1 - 1.1e-25 90.1 0.0 3.5e-17 62.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDO14399.1 - 1.7e-05 23.9 0.2 0.00014 20.9 0.0 2.5 3 1 0 3 3 3 1 Kinase-like APH PF01636.18 EDO14399.1 - 0.32 10.6 0.0 0.53 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C2H2 PF00096.21 EDO14400.1 - 1.3e-12 47.2 12.4 2.9e-06 27.2 2.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO14400.1 - 1.5e-10 40.6 12.2 7.4e-05 22.8 1.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO14400.1 - 7.8e-08 32.2 18.6 1.7e-06 27.9 2.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.10 EDO14400.1 - 4.6e-06 26.2 4.8 0.0019 17.8 0.9 2.8 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.3 EDO14400.1 - 4.7e-05 23.3 11.1 0.017 15.2 3.2 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 EDO14400.1 - 0.023 14.1 3.0 0.19 11.1 0.2 2.9 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 EDO14400.1 - 0.033 14.0 7.7 0.11 12.4 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger GAGA PF09237.6 EDO14400.1 - 0.035 13.7 1.9 0.72 9.4 0.7 2.7 1 1 1 2 2 2 0 GAGA factor zf-Di19 PF05605.7 EDO14400.1 - 0.055 13.6 4.1 0.11 12.6 2.8 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EDO14400.1 - 0.076 13.1 9.1 1.3 9.1 1.2 3.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EDO14400.1 - 2 8.7 12.5 2.2 8.6 0.1 3.1 3 0 0 3 3 2 0 Zinc-finger of C2H2 type RVT_2 PF07727.9 EDO14401.1 - 2.3e-78 262.5 0.0 3e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Glyco_trans_4_4 PF13579.1 EDO14401.1 - 0.019 15.0 0.1 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain rve PF00665.21 EDO14402.1 - 1.1e-23 83.6 0.2 2.3e-23 82.5 0.2 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDO14402.1 - 3.4e-14 52.2 0.3 6.7e-13 48.0 0.0 2.7 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 EDO14402.1 - 0.047 13.2 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Pkinase PF00069.20 EDO14403.1 - 2.4e-44 151.4 0.0 6.5e-44 150.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EDO14403.1 - 1.2e-41 141.6 1.5 1.2e-41 141.6 1.1 2.3 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EDO14403.1 - 5.3e-22 78.1 0.0 4.3e-21 75.1 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDO14403.1 - 0.0028 16.7 1.4 0.0038 16.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ PF01011.16 EDO14403.1 - 0.082 12.4 0.1 1.3 8.6 0.0 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat SR-25 PF10500.4 EDO14403.1 - 0.84 9.0 30.4 0.055 12.9 3.7 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SpoIIE PF07228.7 EDO14404.1 - 2.5e-28 99.1 0.0 3.2e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EDO14404.1 - 4.5e-09 36.0 0.1 0.0018 17.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EDO14404.1 - 0.0031 16.9 0.1 0.0071 15.7 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Exo_endo_phos PF03372.18 EDO14405.1 - 3.8e-21 76.1 0.1 5.2e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_L30 PF00327.15 EDO14406.1 - 1.3e-13 50.2 0.2 1.7e-13 49.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RNB PF00773.14 EDO14408.1 - 1.8e-70 237.7 2.0 4.3e-70 236.5 1.4 1.7 1 0 0 1 1 1 1 RNB domain Pept_tRNA_hydro PF01195.14 EDO14409.1 - 6.1e-38 130.1 0.0 7.7e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase gag_pre-integrs PF13976.1 EDO14410.1 - 1.3e-14 53.5 0.0 4.8e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 GAG-pre-integrase domain Striatin PF08232.7 EDO14414.1 - 7.3e-25 87.8 15.1 3e-23 82.6 1.4 3.3 2 1 2 4 4 4 2 Striatin family bZIP_1 PF00170.16 EDO14414.1 - 0.034 14.0 0.7 0.13 12.2 0.5 2.0 1 0 0 1 1 1 0 bZIP transcription factor Mto2_bdg PF12808.2 EDO14414.1 - 0.065 13.3 1.1 0.18 11.9 0.8 1.8 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3812 PF12757.2 EDO14415.1 - 4.1e-16 59.1 0.8 4.1e-16 59.1 0.6 4.3 3 2 2 5 5 5 1 Protein of unknown function (DUF3812) Proteasome PF00227.21 EDO14416.1 - 7.1e-48 162.4 0.1 9e-48 162.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EDO14416.1 - 5.8e-16 57.4 0.0 1.2e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal DUF3789 PF12664.2 EDO14416.1 - 0.096 12.0 0.1 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) TRAPPC9-Trs120 PF08626.6 EDO14417.1 - 1.7e-281 936.5 30.3 2.5e-281 935.9 21.0 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF3034 PF11231.3 EDO14417.1 - 0.034 13.4 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3034) LSM PF01423.17 EDO14418.1 - 7.2e-13 47.8 0.2 8.4e-13 47.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain Xpo1 PF08389.7 EDO14419.1 - 5.3e-23 81.5 4.1 5.3e-23 81.5 2.9 2.8 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EDO14419.1 - 1.7e-06 27.8 3.8 1.1e-05 25.2 0.1 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain MutS_II PF05188.12 EDO14419.1 - 0.074 13.1 1.1 3.4 7.7 0.0 3.5 4 0 0 4 4 4 0 MutS domain II DUF1811 PF08838.5 EDO14419.1 - 0.092 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) ABC2_membrane PF01061.19 EDO14420.1 - 4.5e-08 32.5 1.5 4.5e-08 32.5 1.0 2.1 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 EDO14420.1 - 0.0023 17.5 0.6 0.0042 16.7 0.4 1.5 1 0 0 1 1 1 1 CDR ABC transporter Flocculin PF00624.13 EDO14421.1 - 0 981.3 775.3 7.8e-14 51.2 17.7 24.2 24 0 0 24 24 24 24 Flocculin repeat Bacteroid_pep PF14406.1 EDO14421.1 - 3.4e-11 43.0 119.6 14 5.9 0.2 22.2 23 0 0 23 23 23 21 Ribosomally synthesized peptide in Bacteroidetes PTB PF08416.8 EDO14423.1 - 0.078 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotyrosine-binding domain SUR7 PF06687.7 EDO14424.1 - 1.1e-29 103.5 13.9 1.3e-29 103.2 9.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EDO14424.1 - 0.05 13.4 3.4 0.082 12.7 2.3 1.3 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 zf-C4H2 PF10146.4 EDO14424.1 - 0.22 11.5 0.1 0.28 11.1 0.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Cuticle_3 PF11018.3 EDO14424.1 - 0.73 9.9 5.7 0.31 11.1 2.1 1.7 2 0 0 2 2 2 0 Pupal cuticle protein C1 POT1 PF02765.12 EDO14425.1 - 5.7e-17 61.9 9.5 5.7e-17 61.9 6.6 2.9 3 1 0 3 3 3 1 Telomeric single stranded DNA binding POT1/CDC13 Flocculin PF00624.13 EDO14426.1 - 4.9e-08 32.6 44.0 3.8e-06 26.6 11.6 4.4 4 2 0 4 4 4 2 Flocculin repeat B_lectin PF01453.19 EDO14426.1 - 0.035 14.0 0.4 5 7.0 0.0 2.2 2 0 0 2 2 2 0 D-mannose binding lectin PMT PF02366.13 EDO14427.1 - 3.6e-85 285.2 15.9 4.1e-85 285.0 11.0 1.0 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.1 EDO14427.1 - 0.00029 20.7 15.0 0.00029 20.7 10.4 2.3 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF4491 PF14898.1 EDO14427.1 - 2 8.5 9.0 1.1 9.4 4.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4491) Med15_fungi PF05397.7 EDO14428.1 - 1.1e-38 131.6 6.7 1.1e-38 131.6 4.6 7.0 4 3 2 6 6 6 1 Mediator complex subunit 15 Zip PF02535.17 EDO14430.1 - 0.0001 21.4 3.1 0.0001 21.4 2.2 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter Trypan_PARP PF05887.6 EDO14430.1 - 0.0066 16.2 24.5 0.013 15.3 17.0 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) EI24 PF07264.6 EDO14430.1 - 1.4 8.2 11.3 0.14 11.5 3.1 2.2 2 1 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) DUF1510 PF07423.6 EDO14430.1 - 2.4 7.4 10.3 3.6 6.9 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) eIF3g PF12353.3 EDO14431.1 - 0.0013 18.6 0.7 0.0025 17.7 0.5 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Glyco_hydro_32N PF00251.15 EDO14432.1 - 5.6e-87 291.9 7.9 7.1e-87 291.6 5.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EDO14432.1 - 2.8e-06 27.6 0.1 1.5e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Macoilin PF09726.4 EDO14433.1 - 5 5.2 41.8 0.23 9.7 24.8 1.7 2 0 0 2 2 2 0 Transmembrane protein Peptidase_S64 PF08192.6 EDO14433.1 - 7.2 4.8 31.0 4.8 5.3 20.4 1.5 1 1 0 1 1 1 0 Peptidase family S64 B56 PF01603.15 EDO14434.1 - 1.5e-145 484.9 15.9 3.8e-138 460.5 8.2 2.2 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) EMP24_GP25L PF01105.19 EDO14435.1 - 7.1e-38 130.1 0.1 8.5e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2481 PF10654.4 EDO14435.1 - 0.063 12.9 0.4 0.092 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) DUF3094 PF11293.3 EDO14435.1 - 0.077 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Ribosomal_S30AE PF02482.14 EDO14435.1 - 0.085 13.3 0.1 0.72 10.3 0.1 2.0 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF3244 PF11589.3 EDO14435.1 - 0.09 12.4 0.3 1.8 8.2 0.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF3244) XhlA PF10779.4 EDO14435.1 - 6 6.8 8.1 1.6 8.6 2.8 1.9 2 0 0 2 2 2 0 Haemolysin XhlA TP6A_N PF04406.9 EDO14436.1 - 3.2e-16 58.7 0.3 1e-15 57.1 0.1 1.9 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF607 PF04678.8 EDO14436.1 - 0.047 13.6 0.4 1.4 8.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF607 Pet127 PF08634.5 EDO14437.1 - 6.7e-104 346.8 6.5 3.1e-103 344.6 4.5 2.0 1 1 0 1 1 1 1 Mitochondrial protein Pet127 Cyclin PF08613.6 EDO14438.1 - 3.5e-13 50.2 0.3 3.5e-13 50.2 0.2 2.6 2 1 0 2 2 2 1 Cyclin Menin PF05053.8 EDO14438.1 - 3.1 5.8 13.4 5.7 4.9 9.3 1.4 1 0 0 1 1 1 0 Menin BAH PF01426.13 EDO14439.1 - 1.7e-09 37.4 1.8 9.5e-09 35.0 0.1 2.5 2 0 0 2 2 2 1 BAH domain C1_1 PF00130.17 EDO14439.1 - 5.9e-05 22.7 6.3 5.9e-05 22.7 4.4 2.6 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EDO14439.1 - 6.9e-05 22.4 14.3 6.9e-05 22.4 9.9 2.8 3 0 0 3 3 3 1 PHD-finger G_glu_transpept PF01019.16 EDO14439.1 - 0.34 9.3 0.0 0.5 8.7 0.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase mRNA_cap_enzyme PF01331.14 EDO14440.1 - 4e-59 199.5 0.2 6.4e-59 198.8 0.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EDO14440.1 - 3.9e-19 68.9 0.5 3.9e-19 68.9 0.3 2.5 2 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EDO14440.1 - 2.8e-06 26.8 0.0 2.8e-06 26.8 0.0 2.2 3 1 0 3 3 3 1 ATP dependent DNA ligase domain BNIP3 PF06553.7 EDO14440.1 - 0.056 12.8 4.6 0.081 12.2 3.2 1.2 1 0 0 1 1 1 0 BNIP3 BAF1_ABF1 PF04684.8 EDO14440.1 - 0.095 11.5 18.8 0.13 11.0 13.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DAP3 PF10236.4 EDO14441.1 - 7e-90 301.0 1.8 9.8e-90 300.6 1.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EDO14441.1 - 6.9e-06 26.1 0.0 1.3e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO14441.1 - 5.6e-05 23.2 0.0 0.00029 20.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EDO14441.1 - 0.00023 21.3 0.6 0.0027 17.9 0.4 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EDO14441.1 - 0.002 17.0 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein NTPase_1 PF03266.10 EDO14441.1 - 0.006 16.3 0.2 0.035 13.8 0.0 2.3 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 EDO14441.1 - 0.0072 15.3 0.1 0.012 14.5 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EDO14441.1 - 0.014 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EDO14441.1 - 0.022 14.4 0.2 0.16 11.6 0.0 2.5 3 0 0 3 3 3 0 NACHT domain Sigma54_activat PF00158.21 EDO14441.1 - 0.028 13.9 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EDO14441.1 - 0.056 12.2 0.4 0.25 10.1 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.1 EDO14441.1 - 0.076 13.3 0.3 0.98 9.7 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EDO14441.1 - 0.089 12.3 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2187 PF09953.4 EDO14441.1 - 0.14 11.8 2.2 3.5 7.4 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) PseudoU_synth_1 PF01416.15 EDO14442.1 - 7.5e-22 77.7 0.1 8.1e-10 39.0 0.0 3.2 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF2344 PF10105.4 EDO14442.1 - 0.015 14.8 0.2 0.31 10.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) RRM_1 PF00076.17 EDO14443.1 - 2.2e-30 104.0 1.6 8.1e-17 60.6 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO14443.1 - 2.8e-20 72.0 0.1 1.4e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO14443.1 - 4.2e-14 52.1 1.2 2.2e-06 27.4 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDO14443.1 - 4.9e-05 22.9 0.1 0.093 12.4 0.0 2.3 2 0 0 2 2 2 2 Limkain b1 AMP-binding PF00501.23 EDO14444.1 - 1.2e-80 270.9 0.0 1.6e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF1106 PF06523.6 EDO14444.1 - 0.02 14.6 1.2 0.18 11.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1106) AMP-binding_C PF13193.1 EDO14444.1 - 0.036 15.0 0.1 0.35 11.8 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain HTH_40 PF14493.1 EDO14444.1 - 0.092 12.9 0.1 0.31 11.3 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain COX6B PF02297.12 EDO14445.1 - 2.7e-20 72.1 8.0 3.3e-20 71.8 5.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CPW_WPC PF09717.5 EDO14445.1 - 0.022 15.3 2.5 0.83 10.3 0.3 2.3 2 0 0 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) SUN PF03856.8 EDO14446.1 - 3.5e-80 268.9 16.6 4.1e-80 268.6 11.5 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF333 PF03891.10 EDO14446.1 - 0.042 13.6 2.6 0.43 10.4 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF333) RVT_2 PF07727.9 EDO14448.1 - 2.6e-43 147.7 0.0 3.3e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4422 PF14393.1 EDO14450.1 - 0.027 14.0 0.6 0.033 13.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) PLDc_2 PF13091.1 EDO14450.1 - 0.044 13.5 0.1 2.1 8.0 0.0 2.2 1 1 1 2 2 2 0 PLD-like domain rve PF00665.21 EDO14451.1 - 6.5e-18 64.9 0.1 2.7e-17 62.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DUF2321 PF10083.4 EDO14451.1 - 0.098 12.1 0.2 0.55 9.7 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) Fungal_trans PF04082.13 EDO14452.1 - 1.5e-30 106.0 1.2 1.7e-30 105.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO14452.1 - 1.2e-07 31.4 13.4 2.1e-07 30.6 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.14 EDO14453.1 - 9.1e-41 139.6 3.8 1.5e-36 125.7 0.6 2.1 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EDO14453.1 - 1.2e-17 64.6 0.0 1.8e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO14453.1 - 4.6e-13 49.2 0.7 9.8e-12 44.9 0.0 3.2 4 1 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDO14453.1 - 6.7e-12 45.7 0.0 8e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDO14453.1 - 1.3e-07 30.9 0.4 1.2e-06 27.7 0.0 2.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EDO14453.1 - 2.1e-07 30.8 0.0 4.7e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EDO14453.1 - 0.00013 20.5 0.0 0.027 12.9 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 EDO14453.1 - 0.00026 20.0 0.0 0.33 9.8 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EDO14453.1 - 0.0013 17.8 0.2 0.023 13.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EDO14453.1 - 0.021 15.2 0.4 1.2 9.5 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EDO14453.1 - 0.022 13.8 0.1 2 7.3 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EDO14453.1 - 0.11 11.3 0.0 0.33 9.8 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EDO14453.1 - 0.16 12.2 0.6 21 5.4 0.1 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding Ctr PF04145.10 EDO14454.1 - 8.3e-29 100.4 18.3 1.9e-26 92.8 12.7 2.1 1 1 0 1 1 1 1 Ctr copper transporter family Abi PF02517.11 EDO14454.1 - 1.4 9.0 6.2 1.3 9.1 0.3 2.1 2 0 0 2 2 2 0 CAAX protease self-immunity Pox_A14 PF05767.7 EDO14454.1 - 1.7 8.6 5.4 9.1 6.3 1.1 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Enolase_C PF00113.17 EDO14455.1 - 3.5e-147 489.1 0.0 3.9e-147 488.9 0.0 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.1 EDO14455.1 - 0.0016 18.3 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EDO14455.1 - 0.0078 15.1 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EDO14455.1 - 0.078 13.5 0.0 0.24 11.9 0.0 1.9 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Helicase_C PF00271.26 EDO14456.1 - 4.7e-15 55.2 0.0 1.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO14456.1 - 1.8e-09 37.3 0.0 1.4e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Sir1 PF11603.3 EDO14456.1 - 5.1e-06 26.6 4.2 5.1e-06 26.6 1.0 2.4 2 0 0 2 2 2 1 Regulatory protein Sir1 Sds3 PF08598.6 EDO14458.1 - 0.044 13.3 3.1 0.073 12.5 2.2 1.4 1 1 0 1 1 1 0 Sds3-like IFT57 PF10498.4 EDO14458.1 - 0.093 11.4 1.4 0.33 9.6 0.6 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Mac PF12464.3 EDO14458.1 - 0.1 12.5 0.3 0.26 11.3 0.1 1.8 2 0 0 2 2 2 0 Maltose acetyltransferase Mon1 PF03164.9 EDO14459.1 - 7.3e-118 393.7 5.8 1.1e-117 393.1 4.0 1.3 1 0 0 1 1 1 1 Trafficking protein Mon1 GIY-YIG PF01541.19 EDO14460.1 - 3e-09 37.0 1.0 4.6e-09 36.5 0.1 1.7 2 0 0 2 2 2 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EDO14460.1 - 0.00023 21.0 8.9 0.00056 19.8 6.2 1.6 1 0 0 1 1 1 1 FANCL C-terminal domain T5orf172 PF10544.4 EDO14460.1 - 0.087 13.2 0.1 0.28 11.5 0.0 1.9 1 1 0 1 1 1 0 T5orf172 domain AAA_2 PF07724.9 EDO14461.1 - 1.6e-35 122.5 2.9 6.4e-35 120.5 2.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EDO14461.1 - 1.4e-14 54.4 0.4 3.4e-14 53.1 0.3 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EDO14461.1 - 9.7e-09 35.0 0.0 3.5e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EDO14461.1 - 8.9e-08 31.9 0.1 2.8e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDO14461.1 - 7.7e-06 26.0 0.4 0.0001 22.4 0.3 2.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EDO14461.1 - 2.5e-05 23.5 0.0 0.012 14.7 0.0 2.8 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EDO14461.1 - 6.6e-05 22.9 0.2 0.0009 19.2 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.21 EDO14461.1 - 0.0001 21.8 0.0 0.042 13.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 EDO14461.1 - 0.00011 22.9 0.2 0.00044 21.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EDO14461.1 - 0.00029 20.8 0.0 0.00081 19.4 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain DEAD PF00270.24 EDO14461.1 - 0.00055 19.4 1.2 0.033 13.6 0.0 3.1 3 1 1 4 4 4 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 EDO14461.1 - 0.00076 18.9 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.7 EDO14461.1 - 0.00099 18.2 0.5 0.009 15.0 0.1 2.5 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EDO14461.1 - 0.001 18.0 0.1 0.0028 16.6 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 EDO14461.1 - 0.0011 18.9 0.6 0.0028 17.5 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.1 EDO14461.1 - 0.0013 19.0 6.9 0.0013 19.0 4.7 3.3 2 1 1 3 3 3 1 AAA domain ResIII PF04851.10 EDO14461.1 - 0.0029 17.4 1.8 0.011 15.5 0.0 2.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit NACHT PF05729.7 EDO14461.1 - 0.0048 16.5 0.1 0.15 11.6 0.0 2.5 3 0 0 3 3 2 1 NACHT domain PhoH PF02562.11 EDO14461.1 - 0.0081 15.4 0.0 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_33 PF13671.1 EDO14461.1 - 0.011 15.5 0.0 0.046 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EDO14461.1 - 0.012 15.1 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EDO14461.1 - 0.02 14.5 2.0 0.028 14.0 0.3 2.1 1 1 1 2 2 2 0 AAA domain SMC_N PF02463.14 EDO14461.1 - 0.031 13.5 0.3 0.13 11.4 0.0 2.2 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.17 EDO14461.1 - 0.032 14.3 0.7 0.26 11.4 0.1 2.6 2 1 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 EDO14461.1 - 0.033 13.9 0.1 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EDO14461.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EDO14461.1 - 0.13 12.5 0.2 0.13 12.5 0.1 2.2 2 1 1 3 3 1 0 ABC transporter AAA_25 PF13481.1 EDO14461.1 - 0.25 10.7 1.4 0.54 9.6 0.2 1.8 1 1 1 2 2 2 0 AAA domain Methyltransf_11 PF08241.7 EDO14462.1 - 1.2e-05 25.6 0.0 4.5e-05 23.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO14462.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Pex14_N PF04695.8 EDO14462.1 - 8.8 6.3 14.2 2.9 7.9 1.9 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MTHFR PF02219.12 EDO14463.1 - 5.7e-85 284.8 0.0 1.2e-84 283.8 0.0 1.5 1 1 0 1 1 1 1 Methylenetetrahydrofolate reductase KcnmB2_inactiv PF09303.5 EDO14464.1 - 4.3 7.1 7.0 0.36 10.6 0.6 2.4 2 0 0 2 2 2 0 KCNMB2, ball and chain domain UBA PF00627.26 EDO14465.1 - 3e-17 61.8 0.4 2.7e-08 33.4 0.0 2.7 3 0 0 3 3 3 2 UBA/TS-N domain UCH PF00443.24 EDO14465.1 - 3.7e-17 62.3 0.1 3.9e-17 62.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO14465.1 - 5.1e-14 52.4 0.1 1.2e-13 51.1 0.1 1.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TFIIIC_sub6 PF10419.4 EDO14466.1 - 0.038 13.4 0.0 0.084 12.3 0.0 1.5 1 0 0 1 1 1 0 TFIIIC subunit DAHP_synth_1 PF00793.15 EDO14467.1 - 4.6e-100 333.7 0.0 5.4e-100 333.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family ATG13 PF10033.4 EDO14469.1 - 4.5e-62 209.5 0.6 8.6e-62 208.6 0.4 1.5 1 0 0 1 1 1 1 Autophagy-related protein 13 Flocculin PF00624.13 EDO14470.1 - 3.3e-267 862.2 692.2 6.5e-14 51.4 17.7 21.8 21 1 1 22 22 22 20 Flocculin repeat Bacteroid_pep PF14406.1 EDO14470.1 - 2.6e-14 53.0 104.4 12 6.1 0.2 20.1 20 0 0 20 20 20 20 Ribosomally synthesized peptide in Bacteroidetes Lumazine_bd PF12870.2 EDO14470.1 - 5.5 7.0 66.1 1.9e+02 2.0 0.1 17.9 19 0 0 19 19 19 0 Lumazine-binding domain Ribosomal_S10 PF00338.17 EDO14471.1 - 1.9e-28 98.1 0.0 2.9e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FtsJ PF01728.14 EDO14472.1 - 2.5e-64 216.5 0.0 3.6e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase ORC2 PF04084.9 EDO14473.1 - 3.2e-114 381.1 6.0 4.5e-114 380.6 4.2 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Pkinase PF00069.20 EDO14474.1 - 3.4e-37 127.9 0.0 7.2e-37 126.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO14474.1 - 5e-25 88.0 0.0 8.8e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDO14474.1 - 0.00058 18.9 0.0 0.0015 17.6 0.0 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDO14474.1 - 0.0067 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO14474.1 - 0.019 14.6 0.0 0.23 11.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3317 PF11779.3 EDO14475.1 - 0.029 13.8 3.0 0.036 13.4 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) DUF4430 PF14478.1 EDO14475.1 - 0.12 12.4 0.5 0.39 10.7 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4430) ECH PF00378.15 EDO14476.1 - 5e-27 94.5 0.2 6.6e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EDO14476.1 - 2.6e-23 82.4 1.5 7e-23 81.0 1.0 1.8 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Focal_AT PF03623.8 EDO14476.1 - 0.0033 16.9 0.9 0.0068 15.8 0.7 1.4 1 0 0 1 1 1 1 Focal adhesion targeting region UCH PF00443.24 EDO14477.1 - 2e-22 79.5 0.2 2e-22 79.5 0.1 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EDO14477.1 - 3e-21 75.2 16.9 5.8e-21 74.3 3.6 2.7 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EDO14477.1 - 3.6e-07 29.9 0.3 3.6e-07 29.9 0.2 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rpp20 PF12328.3 EDO14478.1 - 7.3e-31 106.7 6.8 1.7e-22 79.5 1.7 2.0 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EDO14478.1 - 1.8e-15 56.2 0.2 2.6e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 Alba Inhibitor_I71 PF12628.2 EDO14478.1 - 0.012 15.2 0.4 0.014 15.0 0.2 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DUF1840 PF08895.6 EDO14478.1 - 0.077 13.0 0.2 0.16 12.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Terminase_4 PF05119.7 EDO14478.1 - 0.096 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Phage terminase, small subunit vWA-TerF-like PF10138.4 EDO14478.1 - 0.1 12.3 0.2 0.2 11.4 0.1 1.5 1 1 1 2 2 2 0 vWA found in TerF C terminus TRAP_alpha PF03896.11 EDO14478.1 - 0.42 9.5 2.7 0.51 9.2 1.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Oxidored-like PF09791.4 EDO14479.1 - 5.7e-25 86.5 2.6 1e-24 85.7 1.8 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal HSP70 PF00012.15 EDO14480.1 - 8.3e-177 588.7 1.5 1.1e-176 588.3 1.1 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO14480.1 - 6.5e-09 34.8 0.1 1.1e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 EDO14480.1 - 0.00011 22.0 1.4 0.00011 22.0 1.0 3.8 3 2 0 3 3 3 1 Cell division protein FtsA Peptidase_M22 PF00814.20 EDO14480.1 - 0.2 11.1 0.8 29 4.0 0.0 3.1 1 1 2 3 3 3 0 Glycoprotease family NPL4 PF05021.10 EDO14481.1 - 1.5e-123 411.8 0.2 2e-123 411.4 0.1 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EDO14481.1 - 4.4e-74 247.0 1.0 7.1e-74 246.3 0.7 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EDO14481.1 - 0.0014 18.8 0.0 0.0049 17.1 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF4451 PF14616.1 EDO14481.1 - 0.034 13.8 2.5 0.065 12.9 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Sec66 PF09802.4 EDO14482.1 - 2.7e-76 255.2 2.6 3e-76 255.0 1.8 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Pantoate_transf PF02548.10 EDO14483.1 - 6.4e-100 333.5 0.0 7.5e-100 333.3 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EDO14483.1 - 6.4e-06 25.5 0.0 9.9e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Lactamase_B_2 PF12706.2 EDO14484.1 - 5.8e-34 117.3 0.4 9.5e-34 116.6 0.3 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EDO14484.1 - 8e-12 45.1 0.0 1.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain WD40 PF00400.27 EDO14485.1 - 3.9e-08 32.8 0.3 0.00039 20.1 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Lactonase PF10282.4 EDO14485.1 - 0.05 12.6 0.1 1.2 8.1 0.0 2.5 1 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller tRNA-synt_1b PF00579.20 EDO14486.1 - 2.6e-06 26.7 0.0 3.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) SHOCT PF09851.4 EDO14486.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Short C-terminal domain DUF2423 PF10338.4 EDO14487.1 - 3.7e-19 68.4 3.8 3.7e-19 68.4 2.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Drc1-Sld2 PF11719.3 EDO14487.1 - 0.26 10.3 8.4 0.27 10.2 5.9 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein Ribosomal_L19e PF01280.15 EDO14488.1 - 1.8e-59 199.7 10.8 1.8e-59 199.7 7.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e FTHFS PF01268.14 EDO14489.1 - 7.4e-257 852.7 0.7 1e-256 852.3 0.5 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EDO14489.1 - 1e-71 239.2 0.5 1e-71 239.2 0.3 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EDO14489.1 - 4.9e-34 116.8 1.7 1.3e-33 115.4 1.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 EDO14489.1 - 0.0077 16.0 0.5 0.37 10.6 0.4 2.7 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Saccharop_dh_N PF04455.7 EDO14489.1 - 0.051 13.6 0.0 1.7 8.8 0.0 3.1 3 0 0 3 3 3 0 LOR/SDH bifunctional enzyme conserved region TEA PF01285.13 EDO14490.1 - 4.4e-31 108.4 9.1 3.7e-30 105.4 6.3 2.1 1 1 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-bind_3 PF12776.2 EDO14490.1 - 0.074 13.6 0.6 1.9 9.1 0.1 3.0 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain bZIP_2 PF07716.10 EDO14492.1 - 8.5e-06 25.4 7.7 2.7e-05 23.9 5.4 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDO14492.1 - 0.00075 19.4 15.7 0.002 18.0 9.6 2.3 1 1 1 2 2 2 2 bZIP transcription factor CDC45 PF02724.9 EDO14492.1 - 0.0045 15.0 19.1 0.0055 14.8 13.2 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 EDO14492.1 - 0.074 10.9 25.7 0.084 10.7 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EDO14492.1 - 0.72 8.2 23.1 0.85 8.0 16.0 1.2 1 0 0 1 1 1 0 Daxx Family rve PF00665.21 EDO14493.1 - 1e-07 32.0 0.0 1.9e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EDO14494.1 - 3.9e-14 52.5 0.0 6.3e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4460 PF14687.1 EDO14494.1 - 0.011 15.5 0.3 0.031 14.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) RVP PF00077.15 EDO14495.1 - 0.00051 19.9 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease IIGP PF05049.8 EDO14496.1 - 0.075 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Retrotrans_gag PF03732.12 EDO14497.1 - 1.8e-07 31.1 0.1 4.1e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EDO14497.1 - 8.7e-06 25.4 2.6 1.7e-05 24.4 1.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Fer4_18 PF13746.1 EDO14497.1 - 0.1 13.0 0.4 0.19 12.1 0.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain zf-CCHC_4 PF14392.1 EDO14497.1 - 0.21 11.2 1.9 0.24 11.1 0.3 1.9 2 0 0 2 2 2 0 Zinc knuckle Helicase_C PF00271.26 EDO14498.1 - 2.8e-17 62.3 0.0 4.1e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pox_A21 PF05323.7 EDO14500.1 - 3.2 8.1 13.7 5.6e+03 -2.3 0.0 12.7 6 5 1 5 5 5 0 Poxvirus A21 Protein Sugar_tr PF00083.19 EDO14501.1 - 1.6e-101 340.0 23.4 1.9e-101 339.8 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO14501.1 - 4.6e-24 84.7 28.0 6e-24 84.4 15.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO14502.1 - 2.2e-104 349.5 27.9 3.3e-104 348.9 19.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO14502.1 - 1.4e-28 99.6 27.8 3.3e-27 95.1 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2373 PF10180.4 EDO14503.1 - 5.3e-30 102.7 1.2 1.4e-29 101.3 0.8 1.8 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) MSA-2c PF12238.3 EDO14503.1 - 2.6 7.6 21.1 21 4.7 11.9 2.8 1 1 1 2 2 2 0 Merozoite surface antigen 2c RasGAP PF00616.14 EDO14504.1 - 8.6e-40 136.5 5.5 2e-39 135.2 3.8 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EDO14504.1 - 0.00016 21.4 0.0 0.0004 20.1 0.0 1.7 1 0 0 1 1 1 1 C2 domain CRAL_TRIO PF00650.15 EDO14505.1 - 3e-35 121.0 0.0 4.7e-35 120.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDO14505.1 - 2.5e-11 43.5 1.9 3.9e-11 42.9 0.4 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EDO14505.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.6 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain ALAD PF00490.16 EDO14506.1 - 1.9e-114 381.9 0.0 2.3e-114 381.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase ADH_N PF08240.7 EDO14507.1 - 7.2e-25 86.8 8.0 1.3e-24 86.0 5.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO14507.1 - 2.7e-16 59.2 0.1 5e-16 58.4 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDO14507.1 - 5.7e-07 28.8 0.0 9.5e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF364 PF04016.7 EDO14507.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF364) ADH_zinc_N_2 PF13602.1 EDO14507.1 - 0.0034 18.2 0.0 0.006 17.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 EDO14507.1 - 0.0091 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EDO14507.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EDO14507.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 EDO14507.1 - 0.095 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Mak10 PF04112.8 EDO14508.1 - 1.8e-41 141.1 0.2 4.9e-41 139.7 0.1 1.7 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Citrate_ly_lig PF08218.6 EDO14508.1 - 0.037 13.4 0.9 0.84 9.0 0.1 3.0 2 1 1 3 3 3 0 Citrate lyase ligase C-terminal domain TPR_11 PF13414.1 EDO14509.1 - 1.3e-06 27.9 0.0 0.0076 15.8 0.0 3.6 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 EDO14509.1 - 0.00015 22.0 0.0 0.2 12.3 0.0 4.2 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EDO14509.1 - 0.00017 20.7 2.3 0.048 12.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO14509.1 - 0.00019 21.3 0.0 0.0047 16.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO14509.1 - 0.00019 20.9 0.0 0.023 14.4 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO14509.1 - 0.00059 19.5 0.0 0.0058 16.4 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO14509.1 - 0.0055 17.3 0.0 0.024 15.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO14509.1 - 0.012 15.2 0.0 0.32 10.6 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO14509.1 - 0.023 14.4 0.1 0.5 10.2 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDO14509.1 - 0.05 14.0 0.0 30 5.3 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDO14509.1 - 0.078 13.2 5.6 5.5 7.4 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat Carn_acyltransf PF00755.15 EDO14510.1 - 4.7e-173 576.4 6.1 5.6e-173 576.2 4.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ICMT PF04140.9 EDO14511.1 - 3e-30 104.2 0.4 5.9e-30 103.3 0.2 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EDO14511.1 - 4.4e-15 55.6 3.9 4.4e-15 55.6 2.7 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EDO14511.1 - 9e-05 21.8 0.9 0.00012 21.4 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 EDO14511.1 - 0.0075 15.6 2.2 0.013 14.8 1.5 1.4 1 0 0 1 1 1 1 NnrU protein Rab5ip PF07019.7 EDO14511.1 - 0.0084 16.2 1.4 0.0084 16.2 1.0 3.0 2 1 1 3 3 3 1 Rab5-interacting protein (Rab5ip) AtpR PF12966.2 EDO14511.1 - 1.3 9.2 0.0 1.3 9.2 0.0 3.8 4 0 0 4 4 4 0 N-ATPase, AtpR subunit PINIT PF14324.1 EDO14512.1 - 2.6e-32 111.9 0.3 7.2e-32 110.4 0.2 1.8 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EDO14512.1 - 2.3e-21 75.0 7.3 4e-21 74.2 5.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EDO14512.1 - 2.2e-11 42.9 0.4 4.3e-11 42.0 0.2 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 EDO14512.1 - 2.3e-05 23.8 1.0 4.9e-05 22.7 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EDO14512.1 - 0.0047 16.6 2.1 0.013 15.1 1.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EDO14512.1 - 0.13 12.3 3.5 0.26 11.3 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO14512.1 - 0.32 10.8 4.1 0.58 10.0 2.8 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EDO14512.1 - 0.33 10.8 3.2 0.6 10.0 2.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Cwf_Cwc_15 PF04889.7 EDO14512.1 - 1 9.0 11.7 2 8.0 8.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Aminotran_1_2 PF00155.16 EDO14514.1 - 8.9e-22 77.5 0.0 1.5e-21 76.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Phosphorylase PF00343.15 EDO14515.1 - 0 1024.7 0.6 0 1024.4 0.4 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase MCM PF00493.18 EDO14516.1 - 9.2e-138 458.5 0.6 1.5e-137 457.8 0.4 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDO14516.1 - 2.8e-21 76.2 3.9 6.1e-21 75.1 0.1 2.9 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDO14516.1 - 9e-07 28.2 0.0 4.2e-06 26.0 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EDO14516.1 - 0.0074 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EDO14516.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO14516.1 - 0.089 12.5 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) F_bP_aldolase PF01116.15 EDO14517.1 - 1.8e-95 319.3 0.0 2e-95 319.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II SNAP PF14938.1 EDO14517.1 - 0.061 12.4 0.1 0.1 11.7 0.1 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP eIF-6 PF01912.13 EDO14518.1 - 3.1e-84 281.0 0.3 3.8e-84 280.7 0.2 1.1 1 0 0 1 1 1 1 eIF-6 family Mss4 PF04421.8 EDO14519.1 - 9.5e-17 60.6 4.8 1.4e-12 47.2 0.9 2.2 1 1 1 2 2 2 2 Mss4 protein RunxI PF08504.6 EDO14520.1 - 0.21 12.0 1.6 55 4.2 0.0 3.6 2 1 0 3 3 3 0 Runx inhibition domain CAF1A PF12253.3 EDO14521.1 - 1.2e-23 83.0 11.5 1.2e-23 83.0 8.0 3.9 3 1 0 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EDO14521.1 - 3.2e-11 43.0 77.3 3.2e-11 43.0 53.6 3.5 3 1 1 4 4 4 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal MCM PF00493.18 EDO14522.1 - 6.9e-139 462.2 0.1 1e-138 461.6 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDO14522.1 - 1.5e-22 80.3 1.7 1.5e-22 80.3 1.2 2.8 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 EDO14522.1 - 2.7e-06 27.1 0.0 3e-05 23.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EDO14522.1 - 6.3e-06 25.5 0.0 0.00015 20.9 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDO14522.1 - 0.00095 18.7 0.0 0.0081 15.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Latarcin PF10279.4 EDO14522.1 - 0.021 15.0 0.0 0.15 12.2 0.0 2.6 2 1 0 2 2 2 0 Latarcin precursor Sigma54_activat PF00158.21 EDO14522.1 - 0.051 13.0 0.2 7.2 6.0 0.0 3.3 3 0 0 3 3 3 0 Sigma-54 interaction domain ATP-synt_G PF04718.10 EDO14523.1 - 7e-33 113.3 1.3 8.2e-33 113.1 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DEAD PF00270.24 EDO14524.1 - 1.8e-44 151.1 0.6 8.7e-44 148.9 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO14524.1 - 1e-25 89.3 0.3 6.1e-25 86.8 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1132 PF06575.7 EDO14524.1 - 0.022 15.0 0.7 0.068 13.4 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Nucleoporin_FG PF13634.1 EDO14525.1 - 9.2e-19 67.7 88.7 5.9e-11 42.6 28.1 4.1 3 1 2 5 5 5 3 Nucleoporin FG repeat region zf-C4H2 PF10146.4 EDO14525.1 - 0.096 12.6 0.6 0.17 11.8 0.4 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein DUF1664 PF07889.7 EDO14525.1 - 0.79 9.5 5.5 4.4 7.1 1.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 EDO14526.1 - 2.7e-68 229.9 0.0 5.6e-68 228.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO14526.1 - 8.3e-31 106.9 0.0 1.4e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EDO14526.1 - 3.2e-11 43.5 3.3 3.2e-11 43.5 2.3 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDO14526.1 - 3.3e-09 36.1 0.0 6.3e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EDO14526.1 - 1.1e-06 28.3 0.0 2.4e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 C2 domain YrbL-PhoP_reg PF10707.4 EDO14526.1 - 0.027 13.8 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HSF_DNA-bind PF00447.12 EDO14527.1 - 4.2e-36 123.2 1.1 1.5e-35 121.4 0.7 2.0 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EDO14527.1 - 9.7e-27 93.2 0.2 2.4e-26 91.9 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain DivIC PF04977.10 EDO14527.1 - 0.0093 15.4 2.7 0.034 13.6 1.9 1.9 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.16 EDO14527.1 - 0.025 14.5 3.3 0.074 13.0 2.3 1.8 1 0 0 1 1 1 0 bZIP transcription factor 5-FTHF_cyc-lig PF01812.15 EDO14528.1 - 5.5e-41 140.3 0.0 6.3e-41 140.1 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Aminotran_4 PF01063.14 EDO14529.1 - 2.6e-30 105.6 0.0 3.1e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV RVT_2 PF07727.9 EDO14531.1 - 2.6e-43 147.7 0.0 3.3e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_S26e PF01283.14 EDO14532.1 - 3.2e-50 169.1 9.0 3.8e-50 168.9 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1101 PF06503.6 EDO14532.1 - 0.063 12.0 0.1 0.069 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) WD40 PF00400.27 EDO14533.1 - 9.8e-17 60.1 2.2 0.0011 18.7 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat COX6A PF02046.10 EDO14534.1 - 2.7e-43 146.5 1.4 3e-43 146.4 0.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa MT-A70 PF05063.9 EDO14535.1 - 2.7e-55 186.6 0.2 4.8e-55 185.8 0.1 1.4 1 0 0 1 1 1 1 MT-A70 Serglycin PF04360.7 EDO14535.1 - 0.005 16.5 0.7 0.0089 15.7 0.5 1.4 1 0 0 1 1 1 1 Serglycin SR-25 PF10500.4 EDO14535.1 - 1.1 8.6 13.9 0.04 13.3 3.9 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Hist_deacetyl PF00850.14 EDO14536.1 - 3.1e-82 276.3 0.0 4.3e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain U1snRNP70_N PF12220.3 EDO14538.1 - 3.6e-23 81.6 2.0 3.6e-23 81.6 1.4 3.0 2 1 1 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EDO14538.1 - 1.5e-14 53.3 0.2 5.6e-14 51.5 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO14538.1 - 2.1e-11 43.6 0.2 9.1e-11 41.5 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO14538.1 - 7.2e-05 22.5 0.1 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF619 PF04768.8 EDO14539.1 - 2.4e-51 173.5 0.7 2.4e-51 173.5 0.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EDO14539.1 - 8e-30 103.6 0.0 1.9e-29 102.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EDO14539.1 - 2.5e-19 69.7 0.2 9.7e-19 67.8 0.1 2.0 1 1 1 2 2 2 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 EDO14539.1 - 3.2e-09 36.8 0.0 1.3e-08 34.9 0.0 2.1 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.15 EDO14539.1 - 0.0096 15.8 0.0 0.052 13.4 0.0 2.2 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Mistic PF11458.3 EDO14539.1 - 0.055 13.8 1.0 1.2 9.5 0.1 3.1 3 0 0 3 3 3 0 Membrane-integrating protein Mistic Ran_BP1 PF00638.13 EDO14540.1 - 1.7e-35 121.7 0.1 3.9e-35 120.5 0.1 1.6 1 0 0 1 1 1 1 RanBP1 domain Fis1_TPR_C PF14853.1 EDO14541.1 - 1.7e-20 72.5 0.4 3.3e-20 71.7 0.3 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EDO14541.1 - 1.6e-14 52.9 0.0 2.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat Ribonuc_red_lgC PF02867.10 EDO14542.1 - 4.4e-216 718.6 0.0 5.9e-216 718.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EDO14542.1 - 5.7e-25 86.9 0.0 2.1e-24 85.1 0.0 2.0 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EDO14542.1 - 2.4e-15 56.7 0.1 1.4e-14 54.3 0.0 2.5 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EDO14542.1 - 0.001 17.2 0.1 0.0018 16.4 0.1 1.4 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Sec6 PF06046.8 EDO14543.1 - 1.2e-35 122.6 1.9 1.2e-35 122.6 1.3 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF1788 PF08747.6 EDO14543.1 - 0.012 15.5 0.4 0.012 15.5 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) DUF743 PF05332.6 EDO14544.1 - 0.78 9.7 7.0 13 5.7 4.5 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF743) Cytochrom_C_2 PF01322.15 EDO14544.1 - 1.6 9.2 6.0 4.5 7.8 4.2 1.8 1 1 0 1 1 1 0 Cytochrome C' DUF1664 PF07889.7 EDO14544.1 - 8.1 6.2 14.1 0.33 10.7 3.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) rve PF00665.21 EDO14545.1 - 0.0012 18.9 0.2 0.0056 16.7 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_1 PF00078.22 EDO14546.1 - 2.2e-15 56.6 0.9 2.9e-12 46.4 0.0 2.7 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotrans_gag PF03732.12 EDO14548.1 - 3.6e-06 26.9 0.0 1.4e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 Retrotransposon gag protein DUF592 PF04574.8 EDO14549.1 - 2.3 7.7 10.1 0.36 10.3 3.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF592) XPG_N PF00752.12 EDO14550.1 - 7.2e-35 119.2 0.0 1.9e-34 117.9 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EDO14550.1 - 1.9e-26 91.9 0.0 8.2e-26 89.9 0.0 2.2 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EDO14550.1 - 0.0013 18.9 0.6 0.011 15.9 0.0 2.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold rve PF00665.21 EDO14551.1 - 6.3e-17 61.8 0.0 2.3e-16 59.9 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EDO14551.1 - 7.3e-16 58.1 0.1 2.5e-14 53.1 0.1 2.6 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EDO14551.1 - 0.0012 18.6 1.5 0.052 13.4 1.0 2.9 1 1 0 1 1 1 1 Retroviral aspartyl protease RVT_3 PF13456.1 EDO14551.1 - 0.026 14.3 0.0 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase-like Mannosyl_trans3 PF11051.3 EDO14552.1 - 2.4e-69 233.7 0.7 3.5e-69 233.1 0.5 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EDO14552.1 - 7e-05 22.2 2.2 0.00054 19.3 0.8 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 8 Catalase PF00199.14 EDO14554.1 - 2.1e-151 504.0 4.1 1.3e-150 501.4 2.9 1.8 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDO14554.1 - 1.6e-10 40.6 0.0 8.7e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 Catalase-related immune-responsive Gly_acyl_tr_C PF08444.5 EDO14554.1 - 0.11 12.4 0.1 0.72 9.9 0.0 2.4 3 0 0 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region RPN7 PF10602.4 EDO14555.1 - 1.1e-52 178.0 3.0 1.9e-52 177.1 2.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EDO14555.1 - 5.8e-17 61.9 0.1 1.5e-16 60.5 0.1 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EDO14555.1 - 8.4e-06 25.6 0.4 5.3e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 DUF357 PF04010.8 EDO14555.1 - 0.00035 20.2 0.4 0.001 18.7 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF357) TPR_12 PF13424.1 EDO14555.1 - 0.00061 19.6 1.2 0.097 12.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO14555.1 - 0.0012 18.4 1.4 0.0045 16.6 1.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO14555.1 - 0.002 17.7 0.3 0.64 9.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO14555.1 - 0.0078 16.0 3.9 0.25 11.3 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO14555.1 - 0.027 14.1 1.5 0.073 12.7 0.2 2.1 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.1 EDO14555.1 - 0.052 13.7 0.2 0.18 12.0 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDO14555.1 - 0.058 13.3 2.2 3.9 7.5 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDO14555.1 - 0.11 13.1 0.1 24 5.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO14555.1 - 0.24 11.0 2.4 0.49 10.0 0.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pil1 PF13805.1 EDO14556.1 - 1.7e-153 509.4 0.2 2.2e-153 509.1 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 CDC45 PF02724.9 EDO14556.1 - 0.83 7.6 10.7 1.2 7.0 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EDO14556.1 - 5.2 6.2 16.8 10 5.2 11.7 1.4 1 0 0 1 1 1 0 SDA1 COG4 PF08318.7 EDO14557.1 - 3e-109 364.7 12.8 3e-109 364.7 8.9 1.9 2 0 0 2 2 2 1 COG4 transport protein IF-2B PF01008.12 EDO14558.1 - 5.4e-93 311.0 0.4 5.4e-93 311.0 0.3 2.4 3 0 0 3 3 3 1 Initiation factor 2 subunit family DUF3626 PF12294.3 EDO14558.1 - 0.14 11.1 2.5 1.1 8.2 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3626) DUF2413 PF10310.4 EDO14558.1 - 0.31 9.8 20.2 0.46 9.2 14.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CLASP_N PF12348.3 EDO14559.1 - 9.8e-72 240.9 12.8 1.2e-69 234.1 5.1 2.4 2 0 0 2 2 2 2 CLASP N terminal GTP_cyclohydro2 PF00925.15 EDO14560.1 - 4.8e-58 195.1 0.0 3.5e-53 179.3 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II KH_1 PF00013.24 EDO14561.1 - 1.2e-24 85.6 16.7 6e-11 41.8 0.9 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EDO14561.1 - 3.9e-15 55.1 13.3 3.9e-06 26.3 0.3 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EDO14561.1 - 1.1e-06 28.0 11.6 0.012 15.1 1.4 3.7 3 1 0 3 3 3 3 KH domain KH_5 PF13184.1 EDO14561.1 - 0.041 13.6 10.2 4.5 7.1 0.4 3.9 3 1 0 3 3 3 0 NusA-like KH domain Mito_carr PF00153.22 EDO14562.1 - 3.1e-70 231.9 5.8 6e-25 86.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PsbX PF06596.6 EDO14562.1 - 0.56 9.9 4.3 0.55 9.9 0.4 2.6 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) DUF2524 PF10732.4 EDO14563.1 - 2.7 8.1 6.9 0.64 10.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2524) TatD_DNase PF01026.16 EDO14564.1 - 2.8e-41 141.4 0.0 4.1e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Amidohydro_5 PF13594.1 EDO14564.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase CUE PF02845.11 EDO14565.1 - 3.1e-09 36.1 0.0 5.5e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 CUE domain Di19_C PF14571.1 EDO14565.1 - 4.7 7.5 9.4 0.17 12.2 0.5 2.3 2 1 0 2 2 2 0 Stress-induced protein Di19, C-terminal WD40 PF00400.27 EDO14566.1 - 8.1e-31 104.7 4.1 4.7e-07 29.4 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EDO14566.1 - 3.8e-05 23.4 0.7 0.013 15.1 0.0 3.3 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EDO14566.1 - 0.022 14.2 0.0 0.33 10.4 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MotCF PF09158.5 EDO14566.1 - 0.053 13.1 0.2 0.14 11.8 0.2 1.7 1 0 0 1 1 1 0 Bacteriophage T4 MotA, C-terminal PQQ_3 PF13570.1 EDO14566.1 - 0.06 13.6 0.0 38 4.7 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain BNR PF02012.15 EDO14567.1 - 1.3e-15 54.6 51.2 0.36 10.8 0.1 13.4 13 0 0 13 13 13 10 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EDO14567.1 - 1.5e-05 24.6 0.7 0.38 10.3 0.0 4.9 5 0 0 5 5 5 2 Mo-co oxidoreductase dimerisation domain DUF2208 PF09973.4 EDO14567.1 - 0.22 10.7 0.0 0.42 9.8 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) zf-Dof PF02701.10 EDO14568.1 - 0.15 11.9 1.2 0.3 11.0 0.8 1.4 1 0 0 1 1 1 0 Dof domain, zinc finger SlyX PF04102.7 EDO14569.1 - 0.0014 18.9 3.4 0.4 11.0 0.2 3.6 2 0 0 2 2 2 2 SlyX PspB PF06667.7 EDO14569.1 - 8.3 6.4 7.2 2.6 8.0 0.4 3.4 2 0 0 2 2 2 0 Phage shock protein B CFIA_Pcf11 PF11526.3 EDO14570.1 - 7.4e-33 112.5 2.6 7.4e-33 112.5 1.8 1.9 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 E_Pc_C PF06752.7 EDO14570.1 - 0.00021 20.8 1.2 0.00021 20.8 0.8 2.0 2 0 0 2 2 2 1 Enhancer of Polycomb C-terminus VHS PF00790.14 EDO14570.1 - 0.00025 20.7 0.0 0.0015 18.1 0.0 2.3 2 0 0 2 2 2 1 VHS domain zf-H2C2_2 PF13465.1 EDO14570.1 - 0.03 14.6 1.5 3.1 8.2 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO14570.1 - 0.18 12.2 1.6 3.4 8.1 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO14570.1 - 0.43 11.0 2.3 17 6.0 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Mito_carr PF00153.22 EDO14571.1 - 4.1e-33 112.9 0.5 6.9e-15 54.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_4 PF02390.12 EDO14572.1 - 2.3e-60 203.0 0.1 3.3e-60 202.5 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EDO14572.1 - 2.7e-05 23.8 0.1 5.9e-05 22.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO14572.1 - 5.2e-05 23.7 0.0 8.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO14572.1 - 0.00067 19.9 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO14572.1 - 0.00085 19.3 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO14572.1 - 0.0055 17.1 0.0 0.018 15.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDO14572.1 - 0.029 13.7 0.0 0.11 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EDO14572.1 - 0.052 14.0 0.0 3.9 8.0 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 EDO14572.1 - 0.11 11.4 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Ribosomal_L10 PF00466.15 EDO14573.1 - 4e-09 36.2 0.0 6.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF1507 PF07408.6 EDO14573.1 - 0.039 13.6 0.1 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1507) Trm56 PF01994.11 EDO14573.1 - 0.063 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 hNIFK_binding PF12196.3 EDO14574.1 - 0.027 13.8 0.3 0.027 13.8 0.2 2.8 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK Gam PF06064.6 EDO14574.1 - 0.1 12.6 1.9 0.18 11.9 0.3 2.2 2 0 0 2 2 2 0 Host-nuclease inhibitor protein Gam Sel1 PF08238.7 EDO14575.1 - 9e-23 80.1 10.6 0.00012 22.5 0.0 7.3 7 0 0 7 7 7 5 Sel1 repeat DUF1682 PF07946.9 EDO14576.1 - 2.4e-86 289.5 10.8 2.8e-86 289.2 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Thr_synth_N PF14821.1 EDO14577.1 - 7.9e-27 93.1 0.0 2.7e-26 91.4 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 EDO14577.1 - 1.9e-17 63.4 0.0 3e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ytp1 PF10355.4 EDO14578.1 - 1.2e-106 355.9 12.2 1.2e-106 355.9 8.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EDO14578.1 - 2.6e-30 104.1 6.7 2.6e-30 104.1 4.7 3.1 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) UPF1_Zn_bind PF09416.5 EDO14579.1 - 1.1e-69 232.9 10.2 3.2e-69 231.3 4.4 2.5 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EDO14579.1 - 4.4e-58 195.9 0.0 4.3e-57 192.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EDO14579.1 - 5.5e-53 179.9 1.4 5.5e-53 179.9 0.9 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EDO14579.1 - 1.5e-15 57.2 0.3 6.2e-14 52.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO14579.1 - 7.8e-13 47.9 0.0 3.1e-12 46.0 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 EDO14579.1 - 1.4e-05 25.0 0.0 3.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EDO14579.1 - 2.2e-05 23.6 1.3 0.00013 21.0 0.0 2.8 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EDO14579.1 - 0.00013 21.6 0.0 0.66 9.4 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EDO14579.1 - 0.00084 19.0 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.1 EDO14579.1 - 0.0027 17.7 0.3 0.0058 16.6 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 EDO14579.1 - 0.0046 16.2 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.24 EDO14579.1 - 0.0047 16.4 0.1 0.0098 15.3 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.9 EDO14579.1 - 0.011 14.7 0.0 3.8 6.3 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase HSP20 PF00011.16 EDO14579.1 - 0.017 14.9 0.0 0.066 13.0 0.0 2.0 2 0 0 2 2 1 0 Hsp20/alpha crystallin family T2SE PF00437.15 EDO14579.1 - 0.019 13.8 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EDO14579.1 - 0.042 13.6 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.1 EDO14579.1 - 0.068 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EDO14579.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KaiC PF06745.8 EDO14579.1 - 0.22 10.5 0.0 0.43 9.6 0.0 1.4 1 0 0 1 1 1 0 KaiC GATase_5 PF13507.1 EDO14580.1 - 1.6e-95 318.9 0.0 2.4e-95 318.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EDO14580.1 - 3.8e-47 160.1 0.3 1.4e-26 93.2 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EDO14580.1 - 2.7e-23 82.0 0.0 1.6e-22 79.5 0.0 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain DUF2462 PF09495.5 EDO14581.1 - 3.7e-20 72.4 11.6 5.7e-20 71.8 8.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) NPBW PF15180.1 EDO14581.1 - 0.082 12.5 0.4 0.11 12.1 0.2 1.2 1 1 0 1 1 1 0 Neuropeptides B and W Glutaredoxin PF00462.19 EDO14582.1 - 3e-07 30.3 0.0 6.4e-07 29.2 0.0 1.5 1 1 1 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EDO14582.1 - 0.00027 20.5 0.0 0.00032 20.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.6 EDO14582.1 - 0.0014 18.0 0.5 0.0021 17.5 0.3 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 EDO14582.1 - 0.0023 17.4 0.0 0.0027 17.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EDO14582.1 - 0.017 15.3 0.2 0.091 12.9 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EDO14582.1 - 0.059 13.4 0.3 0.063 13.3 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.1 EDO14582.1 - 0.16 12.1 0.4 0.26 11.4 0.3 1.5 1 1 0 1 1 1 0 Thioredoxin-like MFS_1 PF07690.11 EDO14583.1 - 7.4e-21 74.2 24.3 3.6e-20 71.9 15.6 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily HLH PF00010.21 EDO14583.1 - 0.22 11.2 0.7 0.45 10.2 0.5 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain zf-C2H2_6 PF13912.1 EDO14584.1 - 4.1e-06 26.5 4.6 0.0034 17.2 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EDO14584.1 - 7.6e-05 22.7 9.3 0.0007 19.7 1.7 4.7 5 0 0 5 5 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO14584.1 - 0.0042 17.3 3.0 0.0042 17.3 2.1 5.4 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO14584.1 - 0.011 15.9 3.3 0.011 15.9 2.3 5.2 5 1 1 6 6 6 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDO14584.1 - 0.023 14.8 5.4 1.4 9.1 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SR-25 PF10500.4 EDO14584.1 - 0.052 13.0 26.7 0.035 13.5 6.0 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-RING_3 PF14369.1 EDO14584.1 - 0.067 13.1 5.0 0.31 11.0 0.3 3.3 3 0 0 3 3 3 0 zinc-finger zf-Di19 PF05605.7 EDO14584.1 - 0.17 11.9 10.6 0.48 10.5 3.9 3.5 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Chorion_2 PF03964.10 EDO14584.1 - 0.3 11.6 3.5 4.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Chorion family 2 zf-RING_5 PF14634.1 EDO14584.1 - 1.5 8.5 9.4 15 5.4 0.5 3.4 3 0 0 3 3 3 0 zinc-RING finger domain zf-SNAP50_C PF12251.3 EDO14584.1 - 1.8 7.9 8.4 1.1 8.5 1.1 2.3 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal zf-ISL3 PF14690.1 EDO14584.1 - 3.3 7.8 9.3 0.83 9.7 0.7 3.1 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Flocculin PF00624.13 EDO14585.1 - 2.3e-84 276.9 311.6 2e-15 56.2 9.6 120.6 30 2 91 121 121 121 20 Flocculin repeat Pox_A21 PF05323.7 EDO14585.1 - 0.54 10.6 5.2 4.7e+03 -2.1 0.0 9.9 8 3 0 6 6 6 0 Poxvirus A21 Protein SUR7 PF06687.7 EDO14586.1 - 9.1e-23 80.9 20.9 1.7e-22 80.0 14.5 1.4 1 0 0 1 1 1 1 SUR7/PalI family PAT1 PF09770.4 EDO14586.1 - 2.1 6.4 43.7 2.8 6.0 30.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SNARE PF05739.14 EDO14587.1 - 5.7e-18 64.3 4.1 9e-18 63.7 1.1 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EDO14587.1 - 3.8e-07 30.1 0.5 3.8e-07 30.1 0.4 2.4 1 1 1 2 2 2 1 Syntaxin WHIM1 PF15612.1 EDO14588.1 - 6.1e-06 25.9 0.1 4.7e-05 23.1 0.0 2.6 3 0 0 3 3 3 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF2524 PF10732.4 EDO14588.1 - 3 8.0 8.0 3.4 7.8 2.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) Glycogen_syn PF05693.8 EDO14589.1 - 0 1086.7 0.0 0 1086.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EDO14589.1 - 1.1e-09 37.9 0.0 2.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EDO14589.1 - 6.6e-06 25.7 0.3 1.8e-05 24.3 0.2 1.8 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EDO14589.1 - 4.9e-05 23.5 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain HTH_AraC PF00165.18 EDO14590.1 - 0.011 15.4 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EDO14590.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_12 PF08242.7 EDO14590.1 - 2.3 8.7 5.3 1 9.8 0.0 3.2 3 0 0 3 3 3 0 Methyltransferase domain DUF2321 PF10083.4 EDO14591.1 - 0.018 14.5 0.2 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF482 PF04339.7 EDO14591.1 - 0.049 12.5 2.8 0.018 13.9 0.5 1.4 2 0 0 2 2 2 0 Protein of unknown function, DUF482 GST_C PF00043.20 EDO14592.1 - 3.7e-10 39.6 0.0 6.7e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDO14592.1 - 2.4e-06 27.3 0.0 5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EDO14592.1 - 0.00036 20.6 0.0 0.041 14.0 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EDO14592.1 - 0.0012 19.3 0.0 0.0018 18.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RRM_1 PF00076.17 EDO14593.1 - 0.00024 20.6 0.0 0.7 9.5 0.0 2.9 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO14593.1 - 0.014 15.1 0.6 0.18 11.6 0.0 2.9 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO14593.1 - 0.034 14.1 0.0 0.21 11.5 0.0 2.4 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PilN PF05137.8 EDO14593.1 - 0.073 12.9 0.4 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) PHD_3 PF13922.1 EDO14593.1 - 0.26 11.5 0.9 0.97 9.7 0.0 2.4 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx Flocculin PF00624.13 EDO14594.1 - 4.7e-37 125.5 154.1 1.4e-10 40.7 9.3 8.7 8 0 0 8 8 8 7 Flocculin repeat DUF2140 PF09911.4 EDO14595.1 - 9.7e-27 93.3 42.8 29 3.7 0.0 40.6 24 16 23 62 62 62 3 Uncharacterized protein conserved in bacteria (DUF2140) DUF664 PF04978.7 EDO14595.1 - 0.0075 16.5 2.9 8.3e+02 0.1 0.0 11.4 9 0 0 9 9 9 0 Protein of unknown function (DUF664) Topoisom_I_N PF02919.10 EDO14595.1 - 0.89 8.8 0.0 4.5e+02 -0.1 0.0 6.1 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment BOP1NT PF08145.7 EDO14596.1 - 3.2e-103 344.9 7.4 5.1e-103 344.3 5.1 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EDO14596.1 - 6.1e-28 95.6 7.6 5e-12 45.2 0.5 7.5 7 1 0 7 7 7 4 WD domain, G-beta repeat Colicin_D PF11429.3 EDO14596.1 - 0.031 14.4 0.1 0.07 13.2 0.1 1.5 1 0 0 1 1 1 0 Colicin D Nucleoporin_FG PF13634.1 EDO14597.1 - 1.2e-51 173.7 371.0 3.5e-13 49.7 30.3 10.5 2 2 6 8 8 8 5 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 EDO14597.1 - 2.4e-39 134.3 0.0 4.3e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase BA14K PF07886.6 EDO14597.1 - 0.16 11.6 1.3 0.45 10.2 0.0 2.3 2 0 0 2 2 2 0 BA14K-like protein SRF-TF PF00319.13 EDO14598.1 - 2.3e-25 87.5 0.3 3.4e-25 87.0 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) IncA PF04156.9 EDO14598.1 - 0.084 12.4 12.1 0.13 11.8 8.4 1.4 1 0 0 1 1 1 0 IncA protein TEX19 PF15553.1 EDO14598.1 - 0.23 11.3 9.9 0.36 10.6 6.9 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Na_trans_assoc PF06512.8 EDO14598.1 - 0.83 9.5 11.1 1.2 8.9 7.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Serinc PF03348.10 EDO14598.1 - 2.4 6.7 4.5 3.4 6.2 3.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Endonuc_Holl PF10107.4 EDO14598.1 - 9.2 5.9 10.4 6.3 6.4 3.0 2.3 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase Bap31 PF05529.7 EDO14599.1 - 3.3e-45 153.9 10.9 7.1e-44 149.5 7.6 2.0 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF4446 PF14584.1 EDO14599.1 - 0.0094 15.7 0.2 0.018 14.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) Pox_A30L_A26L PF06086.7 EDO14599.1 - 0.011 15.1 0.4 0.018 14.5 0.3 1.4 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein IncA PF04156.9 EDO14599.1 - 0.014 15.0 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 IncA protein YkyA PF10368.4 EDO14599.1 - 0.02 14.2 1.5 0.029 13.7 1.0 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Anoctamin PF04547.7 EDO14599.1 - 0.041 12.5 0.2 0.056 12.0 0.1 1.3 1 1 0 1 1 1 0 Calcium-activated chloride channel DUF1049 PF06305.6 EDO14599.1 - 0.05 13.0 2.9 6.5 6.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) PC4 PF02229.11 EDO14600.1 - 1e-19 69.4 0.1 1.8e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Lin-8 PF03353.10 EDO14600.1 - 7.3 5.7 13.5 11 5.2 9.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CorA PF01544.13 EDO14601.1 - 1.4e-38 132.5 11.9 1e-20 73.9 0.2 4.2 3 1 0 4 4 4 3 CorA-like Mg2+ transporter protein MinC_N PF05209.8 EDO14601.1 - 0.069 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain HMA PF00403.21 EDO14602.1 - 1.2e-11 44.5 0.1 2.7e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 EDO14602.1 - 5.6e-08 33.0 0.0 8.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) MAP65_ASE1 PF03999.7 EDO14603.1 - 4.1e-79 266.8 45.1 6e-79 266.2 31.3 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) SGS PF05002.10 EDO14604.1 - 1.6e-29 101.4 1.7 1.6e-29 101.4 1.2 2.4 3 0 0 3 3 3 1 SGS domain CS PF04969.11 EDO14604.1 - 2.4e-13 50.4 3.2 2.4e-13 50.4 2.2 2.0 2 0 0 2 2 2 1 CS domain EFhand_Ca_insen PF08726.5 EDO14604.1 - 0.22 11.5 2.0 0.3 11.1 0.1 2.2 2 0 0 2 2 2 0 Ca2+ insensitive EF hand TPR_2 PF07719.12 EDO14604.1 - 1.1 9.3 5.6 11 6.1 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Flavoprotein PF02441.14 EDO14605.1 - 7.1e-52 174.4 1.9 2.5e-51 172.6 1.3 1.9 1 1 0 1 1 1 1 Flavoprotein Nha1_C PF08619.5 EDO14605.1 - 0.056 12.7 24.5 0.018 14.3 13.8 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Tim54 PF11711.3 EDO14605.1 - 1.3 7.5 6.4 3.1 6.2 4.4 1.6 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CIAPIN1 PF05093.8 EDO14606.1 - 1.2e-35 121.6 3.3 2.7e-35 120.4 2.3 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-CSL PF05207.8 EDO14606.1 - 0.69 9.4 6.0 3 7.4 4.2 2.1 1 1 0 1 1 1 0 CSL zinc finger zf-AN1 PF01428.11 EDO14607.1 - 4.1e-09 36.1 11.9 6.9e-09 35.4 8.2 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Ank PF00023.25 EDO14608.1 - 2.8e-17 61.5 0.0 2e-07 30.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EDO14608.1 - 2.7e-16 59.5 0.7 1.8e-12 47.3 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO14608.1 - 1.3e-15 57.5 0.1 2.8e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDO14608.1 - 2.4e-13 49.8 0.0 3.3e-09 36.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO14608.1 - 7.9e-12 44.2 0.1 5.8e-05 22.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 EDO14608.1 - 4.2e-08 33.0 1.8 1.5e-07 31.3 1.3 2.0 1 0 0 1 1 1 1 IPT/TIG domain Chalcone PF02431.10 EDO14608.1 - 0.0021 17.4 0.1 0.0054 16.1 0.1 1.6 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Flocculin PF00624.13 EDO14611.1 - 3.8e-21 74.6 68.1 1.4e-13 50.3 20.3 7.4 8 0 0 8 8 8 4 Flocculin repeat Pyridox_oxidase PF01243.15 EDO14611.1 - 0.11 12.5 0.1 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase zf-H2C2_5 PF13909.1 EDO14611.1 - 0.74 10.1 10.3 2.7 8.3 1.5 3.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain SKG6 PF08693.5 EDO14612.1 - 1e-05 24.7 1.8 1.8e-05 23.9 1.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Myb_DNA-bind_6 PF13921.1 EDO14613.1 - 1.5e-28 98.6 10.1 3e-11 43.2 0.1 4.3 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDO14613.1 - 3.7e-26 90.9 9.7 2.6e-10 40.1 0.1 4.3 4 1 0 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EDO14613.1 - 0.00027 20.7 1.9 0.14 12.0 0.1 2.8 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain CSTF2_hinge PF14327.1 EDO14615.1 - 0.00066 19.7 6.0 0.072 13.1 0.1 4.3 4 0 0 4 4 4 2 Hinge domain of cleavage stimulation factor subunit 2 Pol_alpha_B_N PF08418.5 EDO14616.1 - 1.4e-81 273.7 5.9 1.9e-81 273.3 4.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EDO14616.1 - 2.9e-49 167.1 0.3 5.7e-49 166.1 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Anoctamin PF04547.7 EDO14617.1 - 1.7e-29 102.7 33.6 6.3e-27 94.3 19.9 3.0 2 1 0 2 2 2 2 Calcium-activated chloride channel RIC3 PF15361.1 EDO14617.1 - 1.6 8.9 6.1 1.5 9.0 0.0 2.8 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Ala_racemase_N PF01168.15 EDO14618.1 - 5.4e-42 143.7 0.0 6.5e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DHQS PF01959.11 EDO14618.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) Rep_fac_C PF08542.6 EDO14619.1 - 1.6e-19 69.6 0.8 4.8e-19 68.1 0.1 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EDO14619.1 - 1.3e-12 47.6 0.1 3.4e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EDO14619.1 - 3.5e-09 36.9 0.1 1.4e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 EDO14619.1 - 7.6e-05 22.2 0.8 0.00028 20.4 0.0 2.2 2 1 0 3 3 3 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EDO14619.1 - 0.00033 20.6 0.0 0.00062 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO14619.1 - 0.00039 20.5 0.8 0.0036 17.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EDO14619.1 - 0.0018 18.3 0.6 0.44 10.6 0.0 2.9 3 0 0 3 3 3 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EDO14619.1 - 0.015 14.8 0.0 0.03 13.7 0.0 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EDO14619.1 - 0.019 14.3 0.1 0.047 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain NYD-SP12_N PF15015.1 EDO14619.1 - 0.022 12.9 0.0 0.035 12.3 0.0 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal HrcA_DNA-bdg PF03444.10 EDO14619.1 - 0.024 14.0 0.3 0.057 12.8 0.2 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding AAA_24 PF13479.1 EDO14619.1 - 0.11 12.0 0.2 7.4 6.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ribosomal_L16 PF00252.13 EDO14620.1 - 3.7e-35 120.5 0.2 5.3e-35 120.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA-synt_2d PF01409.15 EDO14621.1 - 9.3e-47 159.2 0.6 9.2e-26 90.5 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EDO14621.1 - 1.2e-26 92.6 0.2 5.1e-26 90.6 0.1 2.1 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain WD-3 PF09765.4 EDO14621.1 - 0.13 11.4 2.8 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 WD-repeat region FAD_binding_1 PF00667.15 EDO14622.1 - 6.8e-26 91.0 0.0 1.6e-25 89.8 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EDO14622.1 - 8.3e-19 68.0 0.0 2.3e-18 66.5 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EDO14622.1 - 3.3e-15 56.6 0.0 1.1e-14 54.9 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PCNA_N PF00705.13 EDO14623.1 - 3.3e-51 172.0 1.8 4.2e-51 171.7 0.5 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EDO14623.1 - 3.5e-47 159.5 0.1 7.9e-47 158.3 0.0 1.6 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 EDO14623.1 - 4.6e-07 28.8 0.3 2.2e-05 23.3 0.2 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EDO14623.1 - 0.00031 19.9 0.0 0.00033 19.8 0.0 1.1 1 0 0 1 1 1 1 Rad9 RRM_5 PF13893.1 EDO14624.1 - 2.3e-14 52.9 0.0 2.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO14624.1 - 1.3e-07 31.1 0.0 2e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO14624.1 - 1.6e-07 31.1 0.0 2.5e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDO14624.1 - 0.083 12.6 0.0 0.1 12.3 0.0 1.4 1 1 0 1 1 1 0 Limkain b1 HA2 PF04408.18 EDO14625.1 - 3.1e-26 91.3 0.1 1.9e-25 88.8 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDO14625.1 - 2.3e-24 85.4 0.0 5.9e-24 84.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.18 EDO14625.1 - 5e-15 55.3 0.4 5e-15 55.3 0.3 2.3 2 0 0 2 2 2 1 S1 RNA binding domain Helicase_C PF00271.26 EDO14625.1 - 5.5e-13 48.5 0.0 2.1e-12 46.6 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO14625.1 - 9.7e-07 28.4 0.2 2.3e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO14625.1 - 1.9e-05 24.8 0.0 5.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EDO14625.1 - 0.00044 19.2 0.0 0.0037 16.2 0.0 2.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_14 PF13173.1 EDO14625.1 - 0.00068 19.5 0.2 0.014 15.3 0.1 3.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDO14625.1 - 0.0053 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EDO14625.1 - 0.0071 16.3 0.0 0.031 14.3 0.0 2.1 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_19 PF13245.1 EDO14625.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EDO14625.1 - 0.14 12.4 6.4 0.32 11.2 0.1 3.6 2 2 0 3 3 3 0 ABC transporter PWI PF01480.12 EDO14625.1 - 0.2 11.7 4.8 3.6 7.7 0.1 3.5 2 1 1 3 3 3 0 PWI domain Proteasome PF00227.21 EDO14626.1 - 2.3e-44 150.9 0.0 2.7e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DNA_primase_S PF01896.14 EDO14627.1 - 2.6e-53 179.7 1.4 4.7e-53 178.8 0.9 1.5 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Cellulase PF00150.13 EDO14628.1 - 7.1e-15 54.9 0.5 2.1e-08 33.7 0.1 3.0 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 EDO14628.1 - 0.0028 17.0 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 WSC PF01822.14 EDO14629.1 - 1e-12 47.8 15.2 1e-12 47.8 10.5 2.8 2 1 0 2 2 2 1 WSC domain DUF1191 PF06697.7 EDO14629.1 - 0.0018 17.1 0.0 0.0029 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 EDO14629.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Gly-zipper_Omp PF13488.1 EDO14629.1 - 0.63 9.7 10.6 0.19 11.3 5.1 1.7 2 0 0 2 2 2 0 Glycine zipper DUF2408 PF10303.4 EDO14630.1 - 7.3e-73 243.0 14.2 7.8e-46 155.5 0.4 4.5 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) PTPA PF03095.10 EDO14630.1 - 0.032 13.3 0.2 2.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Phosphotyrosyl phosphate activator (PTPA) protein Herpes_UL36 PF03586.8 EDO14630.1 - 0.038 13.1 0.8 3.6 6.5 0.0 2.8 2 1 0 3 3 3 0 Herpesvirus UL36 tegument protein MtrG PF04210.8 EDO14630.1 - 0.073 12.7 0.7 10 5.8 0.1 3.3 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4140 PF13600.1 EDO14630.1 - 0.26 11.7 3.3 2.6 8.5 0.1 3.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.7 EDO14630.1 - 1.4 8.6 10.7 1.3 8.8 1.0 4.2 4 1 0 4 4 4 0 Laminin Domain II RNA_binding PF01877.12 EDO14631.1 - 0.44 10.5 5.2 0.12 12.3 0.7 2.2 2 1 0 2 2 2 0 RNA binding gag_pre-integrs PF13976.1 EDO14632.1 - 0.00012 21.6 0.1 0.00024 20.6 0.1 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain TIG PF01833.19 EDO14632.1 - 0.0065 16.4 0.6 0.21 11.5 0.0 2.3 2 0 0 2 2 2 1 IPT/TIG domain rve PF00665.21 EDO14632.1 - 0.067 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Sugar_tr PF00083.19 EDO14633.1 - 5.1e-40 137.4 18.8 1.3e-39 136.1 13.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO14633.1 - 1.5e-24 86.4 26.9 2.9e-20 72.2 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tubulin PF00091.20 EDO14634.1 - 2.4e-71 240.0 0.0 3.2e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDO14634.1 - 6e-49 165.2 0.2 9.4e-49 164.6 0.2 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain MSP PF01716.13 EDO14634.1 - 0.022 13.8 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide ALO PF04030.9 EDO14636.1 - 9.3e-101 336.7 1.2 1.6e-100 336.0 0.2 1.7 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EDO14636.1 - 6.6e-27 93.6 0.0 9.5e-27 93.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SIS_2 PF13580.1 EDO14636.1 - 0.087 12.5 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 SIS domain RecO_C PF02565.10 EDO14636.1 - 0.094 12.5 0.0 0.55 10.0 0.0 2.1 2 0 0 2 2 2 0 Recombination protein O C terminal F-box-like PF12937.2 EDO14637.1 - 8.4e-12 44.6 0.1 1.6e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO14637.1 - 6.6e-10 38.3 0.6 1.2e-09 37.5 0.4 1.5 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EDO14637.1 - 0.0043 16.8 0.2 0.045 13.6 0.1 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat UIM PF02809.15 EDO14637.1 - 0.01 15.3 4.4 0.01 15.3 3.1 4.6 4 0 0 4 4 4 0 Ubiquitin interaction motif Utp14 PF04615.8 EDO14638.1 - 6.2e-213 709.0 89.7 6.2e-213 709.0 62.2 2.0 1 1 1 2 2 2 1 Utp14 protein Rad10 PF03834.9 EDO14639.1 - 1.5e-26 91.9 2.2 2.2e-26 91.3 1.5 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) ERO1 PF04137.10 EDO14640.1 - 1.4e-117 392.7 2.4 1.4e-117 392.7 1.7 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Amidase PF01425.16 EDO14642.1 - 6.6e-91 305.3 0.0 9.3e-91 304.8 0.0 1.2 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 EDO14642.1 - 2.1e-83 279.7 0.0 8.3e-83 277.8 0.0 1.9 2 0 0 2 2 2 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EDO14642.1 - 3.9e-64 215.8 0.0 7.4e-64 214.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 EDO14642.1 - 3.9e-40 137.4 0.0 7.5e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 EDO14642.1 - 2.7e-36 124.0 0.1 8e-36 122.4 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EDO14642.1 - 9.8e-33 112.3 0.0 2.2e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EDO14642.1 - 3.6e-18 65.9 0.0 9e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EDO14642.1 - 6.3e-17 60.9 2.1 6.3e-17 60.9 1.5 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EDO14642.1 - 3.9e-12 46.0 0.0 1.1e-11 44.5 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EDO14642.1 - 8.7e-11 41.1 0.0 3.9e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EDO14642.1 - 5.2e-08 32.4 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EDO14642.1 - 3.1e-05 23.9 0.1 6.2e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EDO14642.1 - 3.8e-05 23.2 0.0 0.00022 20.7 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Toxin_59 PF15537.1 EDO14642.1 - 0.053 13.6 0.0 0.29 11.2 0.0 2.3 2 0 0 2 2 1 0 Putative toxin 59 HlyD PF00529.15 EDO14642.1 - 0.091 12.0 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EDO14642.1 - 0.12 12.0 0.1 0.4 10.3 0.1 1.9 1 0 0 1 1 1 0 Biotin-lipoyl like DUF3182 PF11379.3 EDO14642.1 - 0.38 9.4 0.0 0.69 8.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) FTR1 PF03239.9 EDO14643.1 - 3.1e-102 341.6 5.4 3.6e-102 341.4 3.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family CRA PF06589.6 EDO14643.1 - 0.049 12.9 0.1 7 5.9 0.0 2.7 2 1 0 2 2 2 0 Circumsporozoite-related antigen (CRA) CorA PF01544.13 EDO14644.1 - 0.0015 17.6 13.0 0.0058 15.7 9.0 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein 7TM_GPCR_Srj PF10319.4 EDO14644.1 - 0.046 12.8 0.2 0.66 9.0 0.0 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srj HTH_9 PF08221.6 EDO14644.1 - 0.055 13.3 1.7 2.8 7.8 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Glyco_transf_15 PF01793.11 EDO14645.1 - 5.2e-134 446.3 9.6 6.4e-134 446.0 6.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Tox-HNH-HHH PF15637.1 EDO14645.1 - 0.13 12.0 0.1 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Abhydrolase_6 PF12697.2 EDO14646.1 - 2.4e-26 93.0 0.0 2.9e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO14646.1 - 3.2e-18 66.1 0.0 4.3e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO14646.1 - 1.9e-13 50.4 0.0 3.5e-13 49.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EDO14646.1 - 6.7e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 EDO14646.1 - 0.00011 21.8 0.0 0.00028 20.5 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.7 EDO14646.1 - 0.00019 20.8 0.0 0.0037 16.6 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 EDO14646.1 - 0.0003 20.4 0.1 0.0032 17.0 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 EDO14646.1 - 0.00053 19.1 0.0 0.018 14.1 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 EDO14646.1 - 0.0029 16.6 0.0 0.0081 15.1 0.0 1.7 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.3 EDO14646.1 - 0.009 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EDO14646.1 - 0.016 14.7 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EDO14646.1 - 0.047 13.8 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain F-box-like PF12937.2 EDO14647.1 - 0.0012 18.5 0.0 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF3605 PF12239.3 EDO14648.1 - 6.3e-18 65.1 0.1 7.2e-18 64.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Helicase_C PF00271.26 EDO14649.1 - 2.7e-20 71.9 0.1 8.4e-20 70.4 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO14649.1 - 2.8e-20 72.4 0.0 8.8e-18 64.3 0.0 3.7 2 1 1 4 4 4 1 DEAD/DEAH box helicase ResIII PF04851.10 EDO14649.1 - 1.2e-17 64.3 0.0 1.2e-17 64.3 0.0 4.0 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Potex_coat PF06184.6 EDO14649.1 - 0.085 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Potexvirus coat protein Sec3_C PF09763.4 EDO14650.1 - 1e-179 599.0 26.1 1e-179 599.0 18.1 2.6 2 0 0 2 2 2 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EDO14650.1 - 5e-29 99.9 0.4 1.8e-28 98.2 0.3 2.1 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF3210 PF11489.3 EDO14651.1 - 8.1e-26 90.9 19.1 8.1e-26 90.9 13.2 4.0 2 1 1 3 3 3 1 Protein of unknown function (DUF3210) EF-hand_4 PF12763.2 EDO14652.1 - 5.2e-27 93.6 0.0 1.4e-13 50.4 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EDO14652.1 - 3.2e-06 27.1 0.0 0.00039 20.4 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EDO14652.1 - 0.00023 20.2 0.0 0.044 13.1 0.0 3.4 3 0 0 3 3 3 1 EF hand DUF1720 PF08226.6 EDO14652.1 - 0.00077 19.4 14.9 0.00077 19.4 10.3 10.3 4 2 2 6 6 6 1 Domain of unknown function (DUF1720) Collagen PF01391.13 EDO14652.1 - 0.03 13.8 10.7 0.065 12.7 7.4 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) EF-hand_6 PF13405.1 EDO14652.1 - 0.042 13.7 0.0 6.3 6.9 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain DUF748 PF05359.6 EDO14653.1 - 0.12 12.3 0.5 0.27 11.2 0.3 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF748) DUF221 PF02714.10 EDO14654.1 - 1.5e-102 342.8 18.7 1.5e-102 342.8 13.0 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDO14654.1 - 1.6e-37 128.5 2.0 1.6e-37 128.5 1.4 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EDO14654.1 - 1.5e-13 51.0 0.4 3.1e-13 50.0 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DEAD PF00270.24 EDO14655.1 - 2.3e-37 128.0 0.2 9.9e-37 126.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO14655.1 - 1.8e-17 62.9 0.0 4.3e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO14655.1 - 7.8e-07 29.0 0.1 2.5e-06 27.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EDO14655.1 - 0.0067 16.0 0.0 0.019 14.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain CoaE PF01121.15 EDO14656.1 - 8.1e-60 201.3 0.0 9.8e-60 201.0 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EDO14656.1 - 4.9e-07 30.5 0.0 8.3e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO14656.1 - 2.8e-06 27.6 0.3 1.1e-05 25.7 0.0 2.0 1 1 1 2 2 2 1 AAA domain PRK PF00485.13 EDO14656.1 - 0.00031 20.3 0.9 0.012 15.1 0.0 2.7 2 2 1 3 3 3 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 EDO14656.1 - 0.0019 18.2 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO14656.1 - 0.0021 17.9 0.0 0.0073 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.6 EDO14656.1 - 0.0045 16.8 0.0 0.0091 15.8 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain SKI PF01202.17 EDO14656.1 - 0.0065 16.3 0.0 0.063 13.1 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Cytidylate_kin2 PF13189.1 EDO14656.1 - 0.041 13.7 0.1 0.11 12.3 0.0 1.9 1 1 0 1 1 1 0 Cytidylate kinase-like family ApbA_C PF08546.6 EDO14657.1 - 2.7e-20 72.6 0.3 4.2e-20 72.0 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal FHA PF00498.21 EDO14658.1 - 9.3e-17 60.9 2.1 1.3e-15 57.2 0.0 3.5 4 0 0 4 4 4 1 FHA domain DUF2096 PF09869.4 EDO14658.1 - 0.0033 17.3 4.5 0.0071 16.2 3.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2096) MbeD_MobD PF04899.7 EDO14658.1 - 0.097 12.5 0.8 0.61 10.0 0.3 2.3 1 1 1 2 2 2 0 MbeD/MobD like Methyltransf_32 PF13679.1 EDO14658.1 - 0.13 11.9 0.5 0.41 10.3 0.4 1.9 1 1 0 1 1 1 0 Methyltransferase domain Menin PF05053.8 EDO14658.1 - 0.47 8.5 5.1 0.98 7.5 3.6 1.4 1 0 0 1 1 1 0 Menin Mitovir_RNA_pol PF05919.6 EDO14658.1 - 0.82 8.5 8.0 1.3 7.9 5.6 1.2 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase Cation_efflux PF01545.16 EDO14659.1 - 6.5e-58 196.0 3.5 6.5e-58 196.0 2.4 2.7 3 0 0 3 3 3 1 Cation efflux family DUF2946 PF11162.3 EDO14659.1 - 0.45 10.7 5.3 7.4 6.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Topoisom_bac PF01131.15 EDO14660.1 - 2.7e-96 322.8 0.0 3.5e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EDO14660.1 - 7.7e-21 73.9 0.0 1.7e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF4413 PF14372.1 EDO14660.1 - 0.11 12.5 0.2 0.34 10.8 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) EST1_DNA_bind PF10373.4 EDO14661.1 - 1.7e-52 178.3 4.8 1.7e-52 178.3 3.3 2.3 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EDO14661.1 - 7.3e-24 84.2 6.0 7.3e-24 84.2 4.2 3.1 3 0 0 3 3 3 1 Telomerase activating protein Est1 WD40 PF00400.27 EDO14662.1 - 2.8e-05 23.7 0.5 0.0017 18.1 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2963 PF11178.3 EDO14662.1 - 0.041 13.3 0.1 0.041 13.3 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2963) cobW PF02492.14 EDO14663.1 - 2.6e-40 137.7 0.2 5e-40 136.8 0.0 1.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EDO14663.1 - 8.3e-05 22.2 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 EDO14663.1 - 0.0065 16.1 0.0 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EDO14663.1 - 0.0077 16.3 0.1 0.6 10.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EDO14663.1 - 0.0094 15.8 0.0 0.032 14.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EDO14663.1 - 0.023 14.9 1.5 0.055 13.7 0.1 2.3 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.1 EDO14663.1 - 0.026 14.0 0.3 0.074 12.6 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EDO14663.1 - 0.027 14.3 0.1 0.27 11.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain Arch_ATPase PF01637.13 EDO14663.1 - 0.033 13.9 0.1 0.093 12.4 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 EDO14663.1 - 0.034 14.4 0.4 0.1 12.8 0.1 2.0 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 EDO14663.1 - 0.063 12.7 0.7 0.16 11.3 0.1 2.0 3 0 0 3 3 3 0 AAA-like domain AAA_16 PF13191.1 EDO14663.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EDO14663.1 - 0.09 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 EDO14663.1 - 0.11 12.8 0.4 0.11 12.8 0.3 2.5 3 1 1 4 4 4 0 AAA domain Img2 PF05046.9 EDO14664.1 - 1.5e-24 85.9 0.6 2.6e-24 85.2 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ubiquitin PF00240.18 EDO14665.1 - 1.2e-05 24.6 0.6 1.6e-05 24.1 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EDO14665.1 - 0.039 14.5 0.0 0.043 14.3 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.3 EDO14665.1 - 0.051 13.2 0.3 0.057 13.1 0.2 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Glucosamine_iso PF01182.15 EDO14666.1 - 2e-47 161.5 0.0 3.3e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Macoilin PF09726.4 EDO14666.1 - 0.5 8.6 5.6 0.63 8.2 3.9 1.0 1 0 0 1 1 1 0 Transmembrane protein PQ-loop PF04193.9 EDO14667.1 - 1.7e-21 75.5 9.9 5.4e-15 54.6 0.0 2.9 2 1 0 2 2 2 2 PQ loop repeat P34-Arc PF04045.9 EDO14668.1 - 8.1e-97 323.2 2.5 1.1e-96 322.8 1.7 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc Cation_efflux PF01545.16 EDO14670.1 - 4.5e-05 22.6 15.1 0.0001 21.4 10.5 1.5 1 1 0 1 1 1 1 Cation efflux family Thioredoxin PF00085.15 EDO14671.1 - 2.3e-28 97.8 0.1 3.1e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EDO14671.1 - 1.8e-07 31.2 0.2 1.9e-05 24.6 0.0 2.6 1 1 2 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EDO14671.1 - 2e-06 27.3 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EDO14671.1 - 2.8e-06 27.4 0.1 1.8e-05 24.8 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EDO14671.1 - 4.9e-06 26.2 0.0 8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EDO14671.1 - 0.00014 21.3 0.1 0.0024 17.4 0.0 2.1 1 1 1 2 2 2 1 Redoxin TraF PF13728.1 EDO14671.1 - 0.00062 19.3 0.0 0.00085 18.8 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Phosducin PF02114.11 EDO14671.1 - 0.00096 17.9 0.0 0.0013 17.5 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_7 PF13899.1 EDO14671.1 - 0.0097 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like DUF2847 PF11009.3 EDO14671.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) DSBA PF01323.15 EDO14671.1 - 0.078 12.5 0.3 3.4 7.1 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Glutaredoxin PF00462.19 EDO14671.1 - 0.092 12.7 0.1 0.32 11.0 0.0 1.9 1 1 1 2 2 2 0 Glutaredoxin KaiB PF07689.7 EDO14671.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 KaiB domain Tup_N PF08581.5 EDO14672.1 - 2.9e-27 94.6 12.8 2.9e-27 94.6 8.9 2.0 2 0 0 2 2 2 1 Tup N-terminal Allexi_40kDa PF05549.6 EDO14672.1 - 0.03 13.6 6.8 0.038 13.2 4.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein A2M_recep PF07677.9 EDO14672.1 - 0.54 10.4 3.6 0.9 9.7 0.4 2.3 2 0 0 2 2 2 0 A-macroglobulin receptor DUF948 PF06103.6 EDO14672.1 - 1.2 9.0 3.7 1.6 8.6 2.1 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FadA PF09403.5 EDO14672.1 - 1.4 8.9 8.5 0.57 10.1 4.4 1.5 1 1 0 1 1 1 0 Adhesion protein FadA TMPIT PF07851.8 EDO14672.1 - 1.6 7.7 8.2 2.2 7.2 5.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein FlaC_arch PF05377.6 EDO14672.1 - 2.7 7.9 11.0 11 6.0 0.7 3.4 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.6 EDO14672.1 - 3.1 7.2 16.2 0.28 10.5 4.4 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Mitofilin PF09731.4 EDO14672.1 - 5.4 5.5 23.1 0.23 10.1 7.1 2.0 1 1 1 2 2 2 0 Mitochondrial inner membrane protein Cofilin_ADF PF00241.15 EDO14673.1 - 3.1e-20 72.3 0.0 8.3e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.23 EDO14673.1 - 3.2e-16 58.4 0.9 9.1e-16 56.9 0.6 1.9 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO14673.1 - 2e-15 56.0 0.4 5.1e-15 54.7 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDO14673.1 - 2.8e-08 33.1 0.0 4.9e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_C24 PF03510.9 EDO14673.1 - 0.12 12.5 0.1 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 2C endopeptidase (C24) cysteine protease family CAP PF00188.21 EDO14674.1 - 3.8e-11 43.5 3.1 4.7e-11 43.2 2.2 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family KH_1 PF00013.24 EDO14675.1 - 2.2e-75 248.1 36.6 7.9e-11 41.4 1.8 10.9 10 0 0 10 10 10 8 KH domain KH_3 PF13014.1 EDO14675.1 - 1.2e-47 158.7 32.5 9.2e-08 31.5 0.0 9.5 8 1 0 8 8 8 8 KH domain KH_2 PF07650.12 EDO14675.1 - 9.1e-13 47.5 20.9 6.3e-05 22.4 0.1 7.3 7 1 0 7 7 7 5 KH domain KH_5 PF13184.1 EDO14675.1 - 3.2e-05 23.6 16.9 0.13 12.0 0.3 7.2 6 0 0 6 6 6 1 NusA-like KH domain KH_4 PF13083.1 EDO14675.1 - 7.5e-05 22.2 11.7 0.0032 17.0 0.1 5.4 5 0 0 5 5 5 2 KH domain BMC PF00936.14 EDO14675.1 - 0.00073 19.1 2.7 13 5.5 0.0 5.9 6 0 0 6 6 6 1 BMC domain YpjP PF14005.1 EDO14675.1 - 0.16 11.7 3.4 0.11 12.2 0.2 2.4 2 0 0 2 2 2 0 YpjP-like protein Mitofilin PF09731.4 EDO14676.1 - 1.3e-132 443.4 11.7 8.2e-114 381.3 9.6 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Noelin-1 PF12308.3 EDO14676.1 - 0.063 13.0 0.9 0.33 10.7 0.7 2.2 1 0 0 1 1 1 0 Neurogenesis glycoprotein Actin PF00022.14 EDO14677.1 - 3.2e-94 315.5 0.0 2.3e-93 312.7 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EDO14677.1 - 0.0073 14.9 0.0 0.15 10.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein IBR PF01485.16 EDO14678.1 - 2e-15 56.3 48.6 2e-09 37.2 8.4 3.9 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 EDO14678.1 - 1.6e-06 27.6 13.3 1.6e-06 27.6 9.2 4.9 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO14678.1 - 0.0044 17.0 12.1 0.0044 17.0 8.4 5.2 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) VGCC_alpha2 PF08473.6 EDO14678.1 - 0.062 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd DUF3808 PF10300.4 EDO14679.1 - 1.4e-172 574.5 0.9 1.6e-172 574.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EDO14679.1 - 0.13 11.8 1.4 0.45 10.2 0.1 2.6 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.1 EDO14679.1 - 0.46 11.2 2.6 18 6.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_4 PF12763.2 EDO14680.1 - 7.8e-05 22.3 0.7 0.00041 20.0 0.1 2.4 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Ribosomal_L24e PF01246.15 EDO14681.1 - 1.3e-26 92.2 3.0 1.8e-26 91.7 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 EDO14681.1 - 0.12 12.0 0.9 0.39 10.4 0.6 1.8 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif FabA PF07977.8 EDO14681.1 - 0.13 11.7 0.5 0.28 10.6 0.2 1.6 1 1 0 2 2 2 0 FabA-like domain Adaptin_N PF01602.15 EDO14682.1 - 1.1e-95 321.0 22.9 1.4e-95 320.6 15.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EDO14682.1 - 8.7e-07 29.1 0.4 0.05 13.8 0.0 4.1 3 1 2 5 5 5 3 HEAT repeats DUF1512 PF07431.7 EDO14682.1 - 0.0062 15.3 1.2 0.078 11.7 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1512) VHS PF00790.14 EDO14682.1 - 0.09 12.4 2.3 4.5 6.8 0.0 3.9 4 0 0 4 4 4 0 VHS domain CMS1 PF14617.1 EDO14683.1 - 2.5e-17 62.8 13.5 2.5e-17 62.8 9.4 2.6 1 1 1 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit PTPS PF01242.14 EDO14683.1 - 0.92 9.2 3.9 2.6 7.7 1.9 2.3 2 1 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase zf-C2H2 PF00096.21 EDO14684.1 - 7.2e-07 29.1 20.6 0.0022 18.2 1.7 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO14684.1 - 0.00019 21.5 12.9 0.0016 18.6 0.2 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO14684.1 - 0.0017 18.5 15.4 0.099 13.0 1.0 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO14684.1 - 0.051 13.7 16.4 2 8.6 0.9 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EDO14684.1 - 0.44 10.5 14.9 0.13 12.2 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Ogr_Delta PF04606.7 EDO14684.1 - 0.48 10.1 4.7 4.6 6.9 0.2 2.9 1 1 2 3 3 3 0 Ogr/Delta-like zinc finger 2-oxoacid_dh PF00198.18 EDO14685.1 - 1.7e-78 263.0 0.1 2.2e-78 262.6 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDO14685.1 - 1.1e-16 60.2 0.6 2.1e-16 59.3 0.4 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EDO14685.1 - 0.0042 16.7 0.1 0.34 10.6 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like BioT2 PF15368.1 EDO14685.1 - 0.008 15.9 1.5 0.009 15.7 0.1 1.7 2 0 0 2 2 2 1 Spermatogenesis family BioT2 HlyD_3 PF13437.1 EDO14685.1 - 0.019 15.3 0.0 0.068 13.5 0.0 1.9 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 EDO14685.1 - 0.019 14.6 0.1 0.059 13.0 0.1 1.8 1 1 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.1 EDO14685.1 - 0.027 14.1 0.0 0.08 12.6 0.0 1.8 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 EDO14685.1 - 0.062 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Mcp5_PH PF12814.2 EDO14686.1 - 5.2e-42 142.6 1.3 2.3e-41 140.5 0.0 2.6 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology zf-CCCH PF00642.19 EDO14687.1 - 1.2e-19 69.5 17.8 1.4e-10 40.5 3.4 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EDO14687.1 - 0.015 15.3 11.8 0.022 14.7 1.2 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type DUF629 PF04780.7 EDO14687.1 - 0.042 12.3 3.0 0.065 11.7 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) Jacalin PF01419.12 EDO14687.1 - 0.046 13.6 0.3 0.094 12.5 0.2 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain ENTH PF01417.15 EDO14688.1 - 1.2e-31 109.1 1.0 1.2e-31 109.1 0.7 2.0 2 0 0 2 2 2 1 ENTH domain DUF2393 PF09624.5 EDO14688.1 - 0.0047 16.4 0.5 0.0047 16.4 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2393) SOBP PF15279.1 EDO14688.1 - 0.48 10.7 10.7 0.68 10.2 7.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Nop25 PF09805.4 EDO14688.1 - 3.7 7.6 22.4 2.3 8.2 9.8 2.6 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) Mucin PF01456.12 EDO14688.1 - 4.7 6.9 18.6 10 5.8 12.9 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Pro_isomerase PF00160.16 EDO14689.1 - 5.8e-45 153.2 0.0 6.3e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF1517 PF07466.6 EDO14690.1 - 0.029 13.3 0.3 0.042 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Ku PF02735.11 EDO14691.1 - 3e-32 111.6 0.1 5.5e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EDO14691.1 - 5.7e-32 110.9 0.9 8.3e-32 110.4 0.6 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.23 EDO14691.1 - 0.042 13.5 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Auxin_resp PF06507.8 EDO14691.1 - 0.063 13.1 0.2 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 Auxin response factor Init_tRNA_PT PF04179.7 EDO14692.1 - 1.1e-162 542.0 0.2 1.2e-162 541.8 0.1 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DUF3993 PF13158.1 EDO14692.1 - 0.041 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) Phage_Mu_Gam PF07352.7 EDO14692.1 - 0.088 12.3 0.4 2.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein ATP13 PF12921.2 EDO14693.1 - 3.2e-41 139.6 0.3 1.7e-40 137.2 0.2 2.3 1 0 0 1 1 1 1 Mitochondrial ATPase expression Thr_synth_N PF14821.1 EDO14693.1 - 0.044 13.8 0.7 0.75 9.8 0.0 3.5 2 2 1 3 3 3 0 Threonine synthase N terminus PIG-L PF02585.12 EDO14694.1 - 2.2e-18 67.0 0.1 3.2e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Nab6_mRNP_bdg PF10567.4 EDO14695.1 - 1e-110 369.6 20.0 1e-110 369.6 13.8 3.0 2 1 0 2 2 2 1 RNA-recognition motif RRM PF10378.4 EDO14695.1 - 3.2e-19 68.2 7.7 3.2e-19 68.2 5.4 3.2 2 0 0 2 2 2 1 Putative RRM domain RRM_6 PF14259.1 EDO14696.1 - 1.5e-10 40.9 0.2 1.3e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO14696.1 - 2.3e-08 33.7 1.5 0.0036 17.1 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO14696.1 - 3.8e-07 29.6 0.2 0.00071 19.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO14696.1 - 0.016 15.0 0.3 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Cytomega_UL20A PF05984.7 EDO14696.1 - 0.026 14.7 3.1 0.026 14.7 2.1 2.2 3 0 0 3 3 3 0 Cytomegalovirus UL20A protein S-methyl_trans PF02574.11 EDO14697.1 - 9.1e-66 222.2 0.0 1e-65 222.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.20 EDO14697.1 - 0.018 14.5 0.4 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 Kelch motif PGM_PMM_I PF02878.11 EDO14698.1 - 3.5e-40 136.7 0.0 6.2e-40 135.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EDO14698.1 - 8.6e-18 64.5 0.0 2.3e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EDO14698.1 - 1.6e-14 53.9 0.0 3.3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EDO14698.1 - 7.4e-06 25.8 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NIF PF03031.13 EDO14699.1 - 4.3e-27 94.7 0.3 1.9e-26 92.6 0.0 2.3 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 EDO14699.1 - 4.2e-13 49.2 0.2 1.4e-12 47.5 0.1 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EDO14699.1 - 7.3e-07 28.9 0.1 3e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain Biotin_lipoyl_2 PF13533.1 EDO14699.1 - 0.0055 16.3 0.0 2.8 7.6 0.0 2.6 2 0 0 2 2 2 2 Biotin-lipoyl like TAF8_C PF10406.4 EDO14700.1 - 6.7e-23 80.4 0.3 6.7e-23 80.4 0.2 3.0 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term ubiquitin PF00240.18 EDO14701.1 - 2.9e-19 68.2 0.8 4.8e-19 67.5 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDO14701.1 - 8.5e-10 38.1 0.8 1.4e-09 37.4 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EDO14701.1 - 2.7e-07 30.2 0.0 7.2e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_2 PF14560.1 EDO14701.1 - 0.00026 21.1 0.2 0.00052 20.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EDO14701.1 - 0.004 17.0 0.3 0.011 15.5 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDO14701.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain rve PF00665.21 EDO14702.1 - 2.1e-21 76.2 0.0 4.5e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDO14702.1 - 6.6e-13 48.1 0.0 2.9e-12 46.0 0.0 2.2 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_2 PF07727.9 EDO14703.1 - 3.6e-43 147.3 0.0 5.1e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-LYAR PF08790.6 EDO14704.1 - 0.1 12.3 0.3 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Sir1 PF11603.3 EDO14706.1 - 3.7e-09 36.8 1.2 1e-08 35.3 0.8 1.7 1 0 0 1 1 1 1 Regulatory protein Sir1 ADH_zinc_N PF00107.21 EDO14707.1 - 4.3e-14 52.1 0.1 7e-14 51.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO14707.1 - 0.00046 19.9 0.4 0.0096 15.6 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Flavodoxin_2 PF02525.12 EDO14708.1 - 2.8e-51 173.8 0.0 3.5e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EDO14708.1 - 3.5e-12 46.0 0.0 7.1e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 EDO14708.1 - 1.7e-05 24.1 0.0 0.00017 21.0 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin Hph PF13694.1 EDO14709.1 - 1e-69 234.4 15.1 1e-69 234.4 10.5 2.7 3 0 0 3 3 3 1 Sec63/Sec62 complex-interacting family Zip PF02535.17 EDO14709.1 - 2.2 7.2 4.9 4.3 6.2 3.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Saw1 PF11561.3 EDO14710.1 - 8.9e-80 267.1 12.5 1e-79 266.9 8.7 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Aldedh PF00171.17 EDO14711.1 - 1.2e-16 60.0 0.1 2.5e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family URO-D PF01208.12 EDO14711.1 - 0.013 14.4 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) PLU-1 PF08429.6 EDO14711.1 - 0.014 14.3 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 PLU-1-like protein Mak16 PF04874.9 EDO14712.1 - 9.5e-33 112.3 19.0 9.5e-33 112.3 13.2 2.7 2 1 1 3 3 3 1 Mak16 protein C-terminal region Ribosomal_L28e PF01778.12 EDO14712.1 - 1.5e-32 112.4 4.2 1.5e-32 112.4 2.9 1.8 3 0 0 3 3 3 1 Ribosomal L28e protein family RasGEF PF00617.14 EDO14713.1 - 1.6e-42 145.4 3.0 5.6e-42 143.5 2.1 2.1 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EDO14713.1 - 1.7e-15 56.9 0.5 1.7e-15 56.9 0.3 4.6 6 1 0 6 6 6 1 RasGEF N-terminal motif LDB19 PF13002.2 EDO14714.1 - 2e-98 327.5 0.5 3e-98 326.9 0.4 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EDO14714.1 - 0.00023 20.9 0.0 0.00023 20.9 0.0 2.4 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain CDC27 PF09507.5 EDO14714.1 - 2 7.5 19.8 0.4 9.8 10.6 1.8 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MIR PF02815.14 EDO14715.1 - 1.8e-22 79.8 0.2 3.4e-22 78.9 0.1 1.4 1 1 0 1 1 1 1 MIR domain DUF4131 PF13567.1 EDO14715.1 - 5.6 6.3 7.3 14 5.0 0.2 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Ribosomal_L7Ae PF01248.21 EDO14716.1 - 4.8e-23 80.4 0.3 8e-23 79.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDO14716.1 - 0.00062 19.6 0.1 0.0012 18.6 0.1 1.5 1 1 0 1 1 1 1 RNase P subunit Pop3 RRM_1 PF00076.17 EDO14717.1 - 1.8e-15 56.3 6.4 6.6e-07 28.8 0.3 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO14717.1 - 4.6e-11 42.5 2.0 5.3e-05 23.1 0.2 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DNA_pol3_a_NI PF14480.1 EDO14717.1 - 0.0037 16.8 0.2 0.0037 16.8 0.1 2.2 2 0 0 2 2 2 1 DNA polymerase III polC-type N-terminus I Peptidase_M13 PF01431.16 EDO14717.1 - 0.077 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M13 ABC_tran PF00005.22 EDO14717.1 - 0.51 10.6 3.1 2.3 8.4 2.1 1.9 1 1 0 1 1 1 0 ABC transporter RNA_pol_Rpb1_5 PF04998.12 EDO14717.1 - 0.69 9.1 6.7 0.89 8.7 3.6 1.7 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 5 ABC_tran PF00005.22 EDO14718.1 - 2.3e-58 196.3 0.2 9.7e-34 116.6 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EDO14718.1 - 2.3e-40 138.7 43.1 2.6e-23 82.7 10.0 4.4 4 1 0 4 4 3 3 ABC transporter transmembrane region SMC_N PF02463.14 EDO14718.1 - 3.1e-10 39.6 4.7 7.9e-05 21.9 1.6 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO14718.1 - 2.2e-09 37.7 2.8 3.4e-07 30.5 0.1 5.4 6 2 0 6 6 3 2 AAA domain AAA_29 PF13555.1 EDO14718.1 - 1.7e-08 33.8 0.6 0.00069 19.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EDO14718.1 - 2.9e-07 31.0 6.0 9.9e-06 26.0 0.4 4.3 3 1 1 4 4 3 2 AAA domain DUF258 PF03193.11 EDO14718.1 - 2.5e-06 26.7 0.0 0.036 13.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDO14718.1 - 4.3e-06 27.5 0.0 0.14 12.9 0.0 3.2 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EDO14718.1 - 4.7e-06 25.7 0.1 0.0015 17.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 EDO14718.1 - 4.9e-06 27.0 0.0 0.14 12.6 0.0 3.3 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EDO14718.1 - 5.9e-06 26.2 0.1 0.0084 16.0 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EDO14718.1 - 8.2e-06 25.9 0.1 0.5 10.5 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EDO14718.1 - 9.7e-05 22.4 0.4 0.31 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 EDO14718.1 - 0.00029 20.0 0.0 0.76 8.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.12 EDO14718.1 - 0.00031 20.6 0.1 0.35 10.6 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 EDO14718.1 - 0.00048 19.7 0.0 4.9 6.6 0.0 3.8 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EDO14718.1 - 0.00099 19.4 0.0 2.7 8.3 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EDO14718.1 - 0.0011 18.6 0.5 0.77 9.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EDO14718.1 - 0.0018 17.6 0.0 0.45 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EDO14718.1 - 0.0019 18.3 0.2 5.3 7.2 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EDO14718.1 - 0.0019 17.6 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 EDO14718.1 - 0.002 17.8 0.5 1.8 8.2 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EDO14718.1 - 0.0042 16.9 1.7 1.3 8.8 0.0 3.1 3 0 0 3 3 2 1 Dynamin family cobW PF02492.14 EDO14718.1 - 0.0069 15.8 0.1 0.86 9.0 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EDO14718.1 - 0.01 15.3 0.0 0.45 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Guanylate_kin PF00625.16 EDO14718.1 - 0.028 13.8 0.4 2 7.8 0.0 2.9 3 0 0 3 3 3 0 Guanylate kinase AAA_33 PF13671.1 EDO14718.1 - 0.045 13.6 0.0 5.9 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EDO14718.1 - 0.083 12.4 0.0 8.1 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EDO14718.1 - 0.09 12.5 2.2 2.5 7.9 0.0 3.3 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit ArgK PF03308.11 EDO14718.1 - 0.2 10.3 0.1 0.4 9.4 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 EDO14718.1 - 0.54 10.1 1.0 9 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AA_permease_2 PF13520.1 EDO14719.1 - 1.3e-65 221.6 46.9 1.7e-65 221.2 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO14719.1 - 6.1e-14 51.2 38.7 8.4e-14 50.7 26.8 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2417 PF10329.4 EDO14719.1 - 0.0079 15.6 1.1 0.0079 15.6 0.8 2.8 3 0 0 3 3 3 1 Region of unknown function (DUF2417) DUF2621 PF11084.3 EDO14719.1 - 1.1 8.8 4.1 1.5 8.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2621) DUF2663 PF10864.3 EDO14719.1 - 6.9 6.8 11.9 8 6.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) SET PF00856.23 EDO14720.1 - 3.3e-09 37.2 0.1 1.5e-08 35.1 0.1 2.2 1 1 0 1 1 1 1 SET domain PABP PF00658.13 EDO14721.1 - 4.1e-23 80.8 1.1 6.7e-22 76.9 0.0 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_1 PF00076.17 EDO14721.1 - 6.7e-19 67.2 1.6 7.8e-19 67.0 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO14721.1 - 1.1e-15 57.3 0.0 2.1e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO14721.1 - 3.5e-10 39.5 0.0 9e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.21 EDO14722.1 - 2.4e-47 159.9 0.0 2.7e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO14722.1 - 0.00087 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EDO14722.1 - 0.0095 15.6 0.0 0.017 14.8 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EDO14722.1 - 0.031 14.1 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain IGF2_C PF08365.6 EDO14723.1 - 0.067 12.9 0.2 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide HAD PF12710.2 EDO14724.1 - 4e-13 49.9 0.3 1.3e-12 48.3 0.2 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO14724.1 - 5.2e-13 48.7 0.0 1.4e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EDO14724.1 - 5.4e-11 43.3 2.3 8.2e-09 36.1 1.6 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDO14724.1 - 0.0011 18.5 0.2 0.0027 17.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PolyA_pol PF01743.15 EDO14725.1 - 2.9e-30 105.0 0.0 5.3e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EDO14725.1 - 7.4e-06 25.4 0.0 1.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EDO14725.1 - 0.00057 19.7 0.2 0.0021 17.8 0.1 2.1 1 1 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative MutS_V PF00488.16 EDO14726.1 - 4e-76 255.5 0.0 3.4e-75 252.4 0.0 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EDO14726.1 - 3.3e-44 151.1 0.0 5.5e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EDO14726.1 - 1.3e-31 108.9 0.0 6.9e-31 106.6 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EDO14726.1 - 2.1e-16 59.8 0.2 5.6e-16 58.4 0.1 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EDO14726.1 - 2.3e-14 53.5 0.1 1.9e-13 50.6 0.0 2.4 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.1 EDO14726.1 - 0.029 13.9 0.0 0.097 12.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sec63 PF02889.11 EDO14727.1 - 3.5e-171 568.5 13.1 4.4e-92 308.6 2.5 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EDO14727.1 - 2.7e-42 144.1 0.0 4.7e-28 97.7 0.0 3.0 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EDO14727.1 - 2.6e-09 37.1 0.0 8.5e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDO14727.1 - 3.6e-08 33.1 0.0 2.5e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2870 PF11069.3 EDO14729.1 - 0.028 14.4 0.6 0.04 13.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Ly-6_related PF06579.7 EDO14730.1 - 0.015 15.5 0.1 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein Dfp1_Him1_M PF08630.5 EDO14730.1 - 0.046 13.5 0.1 0.065 13.0 0.1 1.2 1 0 0 1 1 1 0 Dfp1/Him1, central region ODC_AZ PF02100.12 EDO14731.1 - 3.4e-09 36.1 0.0 5.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme TBPIP PF07106.8 EDO14731.1 - 0.016 14.8 0.2 0.026 14.0 0.1 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Arf PF00025.16 EDO14732.1 - 2.5e-46 157.1 0.1 3e-46 156.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDO14732.1 - 4.3e-15 55.4 0.0 5.3e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EDO14732.1 - 7.7e-15 54.5 0.0 9.5e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EDO14732.1 - 8.7e-13 48.8 0.0 1.3e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EDO14732.1 - 9.8e-09 34.9 0.0 7.3e-08 32.0 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EDO14732.1 - 1e-08 34.3 0.7 8.2e-06 24.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDO14732.1 - 2e-07 30.3 0.0 2.6e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EDO14732.1 - 1.9e-05 24.6 0.0 3.5e-05 23.7 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EDO14732.1 - 0.089 12.7 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO14732.1 - 0.091 13.0 0.2 0.33 11.2 0.2 2.0 1 1 0 1 1 1 0 AAA domain EF1G PF00647.14 EDO14734.1 - 1.8e-48 162.6 0.2 3.5e-48 161.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 EDO14734.1 - 1.9e-10 40.7 0.0 5.3e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDO14734.1 - 7e-10 38.7 0.0 2.2e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDO14734.1 - 9.7e-06 25.3 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EDO14734.1 - 5.7e-05 23.5 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDO14734.1 - 0.00046 20.3 0.0 0.00098 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDO14734.1 - 0.046 13.7 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Catalase PF00199.14 EDO14735.1 - 5.2e-170 565.2 4.2 6.4e-170 564.9 2.9 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EDO14735.1 - 5.1e-13 48.6 0.0 2.7e-12 46.3 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive Sgf11 PF08209.6 EDO14736.1 - 1.3e-16 59.5 4.8 2e-16 58.9 3.3 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DUF4125 PF13526.1 EDO14736.1 - 0.0026 17.3 0.1 0.003 17.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4125) zf-C2HC_2 PF13913.1 EDO14736.1 - 0.01 15.4 1.0 0.017 14.7 0.7 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type PRP21_like_P PF12230.3 EDO14736.1 - 0.015 14.7 0.1 0.017 14.6 0.1 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-CpG_bind_C PF12269.3 EDO14736.1 - 0.022 14.2 0.2 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain RNHCP PF12647.2 EDO14736.1 - 0.061 13.1 0.6 0.1 12.4 0.4 1.4 1 0 0 1 1 1 0 RNHCP domain Chordopox_RPO7 PF05864.7 EDO14736.1 - 0.071 13.2 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) zf-RING_UBOX PF13445.1 EDO14737.1 - 3e-16 58.8 1.3 3e-16 58.8 0.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger CLTH PF10607.4 EDO14737.1 - 3.8e-11 42.8 1.1 3.8e-11 42.8 0.7 2.7 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 EDO14737.1 - 0.0008 19.1 1.8 0.00087 19.0 0.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EDO14737.1 - 0.0098 15.6 0.7 0.026 14.2 0.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain FYRN PF05964.9 EDO14737.1 - 0.011 15.1 0.0 5.7 6.4 0.0 2.5 2 0 0 2 2 2 0 F/Y-rich N-terminus zf-C3HC4_2 PF13923.1 EDO14737.1 - 0.091 12.8 0.9 0.24 11.4 0.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO14737.1 - 0.21 11.4 2.6 0.26 11.1 0.2 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Skp1_POZ PF03931.10 EDO14738.1 - 7.6e-16 57.9 0.6 1.4e-15 57.0 0.4 1.4 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EDO14738.1 - 5e-05 23.2 0.2 9.6e-05 22.3 0.2 1.5 1 1 0 1 1 1 1 BTB/POZ domain DUF4264 PF14084.1 EDO14738.1 - 0.011 15.0 0.4 0.025 13.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Vps16_N PF04841.8 EDO14739.1 - 5.3e-76 255.7 2.0 5.3e-76 255.7 1.4 1.5 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.7 EDO14739.1 - 1.7e-71 240.7 8.4 2.8e-71 240.0 5.8 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Syntaxin PF00804.20 EDO14741.1 - 2.4e-18 66.1 1.3 2.4e-18 66.1 0.9 3.3 4 1 0 4 4 4 1 Syntaxin SNARE PF05739.14 EDO14741.1 - 2.5e-17 62.2 3.5 2.5e-17 62.2 2.4 2.7 2 1 1 3 3 3 1 SNARE domain Sed5p PF11416.3 EDO14741.1 - 1.2e-13 50.2 3.2 1.2e-13 50.2 2.3 2.6 3 0 0 3 3 3 1 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 EDO14741.1 - 0.0001 22.0 2.0 0.00023 20.9 0.7 2.1 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus MCPsignal PF00015.16 EDO14741.1 - 0.0082 15.7 1.0 0.0082 15.7 0.7 3.0 2 1 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 EDO14741.1 - 0.084 12.6 0.2 0.084 12.6 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF745 PF05335.8 EDO14741.1 - 3.2 7.2 12.6 0.29 10.6 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF745) Snf7 PF03357.16 EDO14742.1 - 7.3e-47 158.9 19.0 7.3e-47 158.9 13.2 2.0 1 1 1 2 2 2 1 Snf7 DASH_Dad4 PF08650.5 EDO14742.1 - 0.052 13.4 1.3 0.052 13.4 0.9 2.4 2 1 1 3 3 3 0 DASH complex subunit Dad4 NuA4 PF09340.5 EDO14742.1 - 0.52 9.9 4.3 0.22 11.1 1.0 1.9 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 Snapin_Pallidin PF14712.1 EDO14742.1 - 1 9.7 15.8 0.19 12.0 6.0 3.0 2 1 2 4 4 4 0 Snapin/Pallidin Syntaxin-6_N PF09177.6 EDO14742.1 - 2.9 8.3 9.4 1.2 9.5 1.1 2.8 2 2 0 2 2 2 0 Syntaxin 6, N-terminal IncA PF04156.9 EDO14742.1 - 4 6.9 14.6 25 4.3 10.1 2.2 1 1 0 1 1 1 0 IncA protein RPW8 PF05659.6 EDO14742.1 - 4.5 6.8 11.3 0.57 9.7 4.0 2.3 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Abhydrolase_1 PF00561.15 EDO14743.1 - 2.2e-23 83.0 0.0 3.2e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EDO14743.1 - 5e-20 70.6 0.1 1e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EDO14743.1 - 3.5e-06 27.0 0.0 6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO14743.1 - 9e-05 22.2 0.0 0.00099 18.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDO14743.1 - 0.00059 19.3 0.0 0.16 11.4 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 EDO14743.1 - 0.0014 18.1 0.0 0.35 10.2 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Cutinase PF01083.17 EDO14743.1 - 0.03 14.0 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase L31 PF09784.4 EDO14744.1 - 4.5e-43 145.5 2.5 5.9e-43 145.1 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cmc1 PF08583.5 EDO14745.1 - 2e-19 69.1 7.3 2.6e-19 68.7 5.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4434 PF14488.1 EDO14745.1 - 0.017 14.8 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) COX17 PF05051.8 EDO14745.1 - 0.066 13.2 5.3 0.45 10.5 0.4 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.8 EDO14745.1 - 0.25 11.3 5.9 0.99 9.4 0.6 2.3 1 1 1 2 2 2 0 CHCH domain SAE2 PF08573.5 EDO14745.1 - 0.32 11.7 2.1 0.52 11.0 1.4 1.4 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus WD40 PF00400.27 EDO14746.1 - 2.6e-56 185.6 6.7 2.6e-09 36.6 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EDO14746.1 - 5.5e-06 26.2 0.9 0.00039 20.1 0.0 3.1 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDO14746.1 - 0.00012 20.4 7.7 0.1 10.7 0.3 4.4 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDO14746.1 - 0.0027 16.5 1.3 0.79 8.4 0.3 3.5 1 1 0 3 3 3 2 Nup133 N terminal like SF3b10 PF07189.6 EDO14746.1 - 0.067 13.0 0.0 0.26 11.1 0.0 2.0 1 1 0 1 1 1 0 Splicing factor 3B subunit 10 (SF3b10) DUF1513 PF07433.6 EDO14746.1 - 0.082 11.7 0.0 1 8.2 0.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Peptidase_M3 PF01432.15 EDO14747.1 - 8.7e-136 453.5 0.0 1.1e-135 453.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EDO14747.1 - 0.35 10.2 0.3 0.56 9.5 0.2 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Mur_ligase_M PF08245.7 EDO14748.1 - 9.3e-08 32.3 0.1 2.2e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain M20_dimer PF07687.9 EDO14748.1 - 0.078 12.7 0.0 12 5.7 0.0 2.7 2 1 0 2 2 2 0 Peptidase dimerisation domain She2p PF11435.3 EDO14749.1 - 1.3e-87 292.4 3.2 1.5e-87 292.3 2.2 1.0 1 0 0 1 1 1 1 RNA binding protein She2p Aldedh PF00171.17 EDO14750.1 - 8.1e-70 235.4 0.0 9.6e-70 235.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TPP_enzyme_N PF02776.13 EDO14751.1 - 1.9e-58 196.7 0.1 5.3e-58 195.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EDO14751.1 - 8.7e-49 165.0 0.0 2e-47 160.6 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDO14751.1 - 6.5e-38 129.5 0.7 2.6e-37 127.6 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EDO14751.1 - 0.037 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CO_dh PF02552.11 EDO14751.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TAF8_C PF10406.4 EDO14752.1 - 0.0065 16.5 0.3 0.014 15.3 0.2 1.5 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Oxysterol_BP PF01237.13 EDO14753.1 - 2e-93 312.7 0.1 2.6e-93 312.3 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein SID PF11778.3 EDO14753.1 - 0.059 13.2 0.4 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 Septation initiation PPI_Ypi1 PF07491.6 EDO14755.1 - 5.1e-19 67.6 12.6 5.1e-19 67.6 8.7 2.2 2 1 0 2 2 2 1 Protein phosphatase inhibitor Slp PF03843.8 EDO14755.1 - 0.083 11.8 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family CDC45 PF02724.9 EDO14755.1 - 0.69 7.8 12.1 0.8 7.6 8.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Herpes_DNAp_acc PF04929.7 EDO14755.1 - 3.7 6.4 5.8 4.3 6.2 4.0 1.3 1 1 0 1 1 1 0 Herpes DNA replication accessory factor Nic96 PF04097.9 EDO14756.1 - 3.8e-216 718.9 12.7 4.7e-216 718.6 8.8 1.1 1 0 0 1 1 1 1 Nup93/Nic96 MmgE_PrpD PF03972.9 EDO14757.1 - 6.2e-154 512.4 0.0 7.3e-154 512.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Citrate_synt PF00285.16 EDO14758.1 - 1e-94 317.1 0.0 1.2e-94 316.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase EAP30 PF04157.11 EDO14759.1 - 1.9e-51 174.3 0.1 2.1e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Pil1 PF13805.1 EDO14760.1 - 3.6e-149 495.2 0.6 4.4e-149 495.0 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.5 EDO14760.1 - 0.0064 16.3 0.1 0.54 10.1 0.0 2.6 2 0 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit FAM92 PF06730.6 EDO14760.1 - 0.066 12.5 1.3 0.16 11.3 0.9 1.7 1 1 0 1 1 1 0 FAM92 protein PPR_2 PF13041.1 EDO14761.1 - 9.6e-15 54.2 1.7 1.5e-06 28.0 0.0 4.3 4 1 1 5 5 5 2 PPR repeat family PPR_3 PF13812.1 EDO14761.1 - 1.6e-05 24.7 0.0 5.1 7.6 0.0 4.2 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.15 EDO14761.1 - 0.022 14.7 0.7 5.1 7.2 0.0 3.8 3 0 0 3 3 3 0 PPR repeat PPR_1 PF12854.2 EDO14761.1 - 0.46 10.0 2.9 7.1 6.2 0.0 3.7 5 0 0 5 5 5 0 PPR repeat Patched PF02460.13 EDO14762.1 - 2.5e-58 197.7 34.3 3.9e-30 104.4 5.3 2.9 1 1 1 2 2 2 2 Patched family Sterol-sensing PF12349.3 EDO14762.1 - 7.3e-39 132.6 32.2 1.2e-37 128.7 7.1 2.4 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EDO14762.1 - 0.4 9.3 22.6 0.0088 14.7 1.0 2.2 2 0 0 2 2 2 0 MMPL family Gti1_Pac2 PF09729.4 EDO14763.1 - 6.9e-55 185.4 0.8 6.9e-55 185.4 0.5 3.5 3 0 0 3 3 3 2 Gti1/Pac2 family AAA_24 PF13479.1 EDO14763.1 - 0.04 13.4 6.0 0.097 12.2 4.2 1.6 1 0 0 1 1 1 0 AAA domain DUF4175 PF13779.1 EDO14763.1 - 4.5 4.8 15.1 6.1 4.4 10.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mito_carr PF00153.22 EDO14764.1 - 8.6e-75 246.5 3.0 3.3e-25 87.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Thioredoxin PF00085.15 EDO14765.1 - 6e-23 80.5 0.2 5.5e-19 67.7 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EDO14765.1 - 2.9e-07 30.4 6.0 2e-05 24.4 1.2 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Erf4 PF10256.4 EDO14765.1 - 0.031 14.1 0.7 0.41 10.5 0.1 2.6 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Thioredoxin_8 PF13905.1 EDO14765.1 - 0.048 13.7 3.7 1.7 8.7 0.1 3.8 3 0 0 3 3 3 0 Thioredoxin-like SNARE PF05739.14 EDO14766.1 - 2.1e-08 33.6 1.3 3.2e-08 33.1 0.9 1.3 1 0 0 1 1 1 1 SNARE domain Sipho_Gp157 PF05565.6 EDO14766.1 - 0.027 14.0 0.5 0.034 13.7 0.3 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 Use1 PF09753.4 EDO14766.1 - 0.058 12.8 0.2 0.064 12.6 0.2 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 XFP PF03894.10 EDO14766.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Sec20 PF03908.8 EDO14766.1 - 0.11 12.2 4.0 1.1 9.0 0.2 2.1 1 1 1 2 2 2 0 Sec20 MttA_Hcf106 PF02416.11 EDO14766.1 - 1 8.5 5.3 2.5 7.2 3.7 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family Synaptobrevin PF00957.16 EDO14766.1 - 3.4 7.3 8.2 6.8 6.3 5.7 1.6 1 1 0 1 1 1 0 Synaptobrevin ParA PF10609.4 EDO14767.1 - 3.7e-37 126.0 0.0 6.7e-37 125.2 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EDO14767.1 - 1.6e-17 63.5 0.0 2.9e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EDO14767.1 - 1.8e-07 30.5 0.0 1e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 EDO14767.1 - 5.2e-06 26.4 0.0 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EDO14767.1 - 6.4e-06 25.4 0.9 4.1e-05 22.7 0.2 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 EDO14767.1 - 0.0039 16.0 0.1 0.0057 15.4 0.1 1.2 1 0 0 1 1 1 1 ArgK protein DUF258 PF03193.11 EDO14767.1 - 0.036 13.2 0.1 0.078 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 YhjQ PF06564.7 EDO14767.1 - 0.039 13.3 0.0 0.12 11.7 0.0 1.7 1 1 0 1 1 1 0 YhjQ protein APS_kinase PF01583.15 EDO14767.1 - 0.059 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.1 EDO14767.1 - 0.071 12.5 0.2 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 EDO14767.1 - 0.074 12.2 0.3 0.67 9.0 0.1 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family IstB_IS21 PF01695.12 EDO14767.1 - 0.08 12.3 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_26 PF13500.1 EDO14767.1 - 0.13 11.8 0.3 4 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf-C4_ClpX PF06689.8 EDO14767.1 - 0.16 11.4 3.5 0.31 10.5 2.4 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger Syja_N PF02383.13 EDO14768.1 - 1.8e-61 207.6 5.0 1.8e-61 207.6 3.5 1.6 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.18 EDO14768.1 - 1e-19 71.4 0.0 1.8e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PMI_typeI PF01238.16 EDO14769.1 - 5.3e-151 502.8 0.1 6.4e-151 502.5 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EDO14769.1 - 0.00017 21.2 0.0 0.029 14.0 0.0 2.6 2 0 0 2 2 2 2 AraC-like ligand binding domain GldH_lipo PF14109.1 EDO14769.1 - 0.029 14.5 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 GldH lipoprotein Cupin_2 PF07883.6 EDO14769.1 - 0.059 12.8 0.0 15 5.2 0.0 2.3 2 0 0 2 2 2 0 Cupin domain HIM1 PF08732.5 EDO14770.1 - 4.4e-10 38.5 0.1 9.7e-07 27.5 0.0 2.7 1 1 2 3 3 3 3 HIM1 NAD_binding_10 PF13460.1 EDO14770.1 - 1.5e-09 38.1 0.0 2.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EDO14770.1 - 0.00044 19.5 0.0 0.001 18.3 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EDO14770.1 - 0.0057 16.1 0.0 0.015 14.7 0.0 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDA1_CD39 PF01150.12 EDO14771.1 - 2.8e-141 470.9 0.1 3.5e-141 470.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EDO14771.1 - 0.082 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family GN3L_Grn1 PF08701.6 EDO14772.1 - 4.5e-26 90.5 16.8 6.9e-26 89.9 11.6 1.3 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase Wbp11 PF09429.5 EDO14772.1 - 0.033 14.1 4.6 0.033 14.1 3.2 2.4 2 0 0 2 2 2 0 WW domain binding protein 11 DUF4355 PF14265.1 EDO14772.1 - 0.83 9.6 15.6 1.2 9.0 10.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) PQ-loop PF04193.9 EDO14773.1 - 1.6e-10 40.3 7.3 9.8e-08 31.4 1.7 2.9 2 0 0 2 2 2 2 PQ loop repeat ARD PF03079.9 EDO14774.1 - 5e-46 156.5 1.7 5.7e-46 156.3 1.2 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EDO14774.1 - 3.6e-09 36.0 0.0 6.2e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EDO14774.1 - 0.00027 20.6 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EDO14774.1 - 0.00031 20.2 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Cupin GPI PF06560.6 EDO14774.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Oxidored_FMN PF00724.15 EDO14775.1 - 2e-119 398.6 0.0 2.3e-119 398.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EDO14776.1 - 6.1e-94 314.7 0.0 7.1e-94 314.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Anp1 PF03452.9 EDO14777.1 - 1.2e-122 408.2 0.0 1.2e-122 408.2 0.0 3.4 2 1 1 3 3 3 1 Anp1 PAT1 PF09770.4 EDO14777.1 - 1.3 7.1 77.0 1.8 6.7 53.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UBA PF00627.26 EDO14778.1 - 5.1e-21 73.8 9.7 2.6e-12 46.1 0.5 2.9 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 EDO14778.1 - 5.3e-16 57.7 1.4 1.2e-15 56.5 1.0 1.6 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 EDO14778.1 - 1.5e-13 49.9 0.7 3.9e-13 48.6 0.5 1.6 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 EDO14778.1 - 1.5e-07 30.9 0.9 5.3e-07 29.2 0.6 2.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EDO14778.1 - 0.0003 20.6 1.2 0.00073 19.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Med15 PF09606.5 EDO14778.1 - 0.00058 18.2 19.6 0.00077 17.8 13.6 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2407 PF10302.4 EDO14778.1 - 0.0016 18.5 0.7 0.0016 18.5 0.5 2.0 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain UBA_3 PF09288.5 EDO14778.1 - 0.0036 16.8 0.2 3 7.5 0.0 2.8 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain APC_CDC26 PF10471.4 EDO14778.1 - 1.1 10.0 15.5 9.3 7.0 4.7 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 NAD_kinase PF01513.16 EDO14779.1 - 1.3e-71 240.7 0.0 1.6e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase SH3_9 PF14604.1 EDO14779.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain GDA1_CD39 PF01150.12 EDO14780.1 - 1.4e-106 356.6 0.0 1.8e-106 356.2 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Isy1 PF06246.7 EDO14781.1 - 1.2e-43 149.3 12.1 6.4e-39 133.8 6.5 2.0 1 1 1 2 2 2 2 Isy1-like splicing family Mistic PF11458.3 EDO14781.1 - 0.016 15.6 0.1 0.039 14.3 0.1 1.6 1 0 0 1 1 1 0 Membrane-integrating protein Mistic Clat_adaptor_s PF01217.15 EDO14781.1 - 0.035 13.8 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Clathrin adaptor complex small chain MRP-L28 PF09812.4 EDO14781.1 - 0.31 10.8 4.6 0.54 10.0 1.3 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 FAD_binding_2 PF00890.19 EDO14782.1 - 5.6e-68 229.6 0.0 6.7e-68 229.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDO14782.1 - 1.7e-08 33.7 0.0 1.1e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO14782.1 - 4.8e-08 32.9 0.0 1.6e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDO14782.1 - 9.5e-08 31.4 1.4 3.4e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EDO14782.1 - 4.6e-07 29.9 0.0 0.00026 20.9 0.0 3.1 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO14782.1 - 1e-05 25.7 0.0 0.00025 21.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDO14782.1 - 0.00017 20.2 0.4 0.02 13.3 0.0 2.8 2 1 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EDO14782.1 - 0.0035 16.4 0.0 0.0068 15.5 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EDO14782.1 - 0.0067 16.2 0.0 0.044 13.5 0.0 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EDO14782.1 - 0.0079 15.2 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EDO14782.1 - 0.0098 15.0 0.0 0.031 13.3 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EDO14782.1 - 0.02 13.7 0.8 0.4 9.4 0.0 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EDO14782.1 - 0.067 12.0 0.1 0.14 11.0 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Zn_clus PF00172.13 EDO14784.1 - 0.00068 19.4 3.0 0.00068 19.4 2.1 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EDO14784.1 - 0.1 12.7 2.1 0.11 12.6 1.4 1.2 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region AA_permease PF00324.16 EDO14786.1 - 2.5e-118 395.4 46.1 2.8e-118 395.2 32.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO14786.1 - 9.3e-37 126.5 49.2 1.1e-36 126.2 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EDO14787.1 - 2.8e-08 32.8 57.1 8.8e-07 27.9 37.8 4.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO14787.1 - 0.00025 19.7 10.7 0.00025 19.7 7.4 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 EDO14789.1 - 1.1e-34 119.6 33.1 2.3e-34 118.6 22.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EDO14789.1 - 0.0044 15.2 3.3 0.0068 14.6 2.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SieB PF14163.1 EDO14789.1 - 0.13 11.8 3.5 0.09 12.3 0.3 2.2 2 0 0 2 2 2 0 Superinfection exclusion protein B Use1 PF09753.4 EDO14789.1 - 2.4 7.5 7.0 3.3 7.0 4.9 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 RseC_MucC PF04246.7 EDO14789.1 - 7.6 6.1 6.1 5.9 6.4 0.5 2.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PLU-1 PF08429.6 EDO14790.1 - 2.8e-15 56.0 7.4 0.11 11.3 0.0 6.5 1 1 6 7 7 7 7 PLU-1-like protein PSDC PF12588.3 EDO14790.1 - 2.7e-10 40.0 16.1 6.4 6.3 0.1 10.3 1 1 8 9 9 9 3 Phophatidylserine decarboxylase NPV_P10 PF05531.7 EDO14790.1 - 1.2e-05 25.4 63.2 85 3.5 4.1 12.7 1 1 1 2 2 1 0 Nucleopolyhedrovirus P10 protein DUF1687 PF07955.6 EDO14790.1 - 0.00033 20.6 32.7 18 5.3 0.3 11.3 1 1 7 8 8 8 0 Protein of unknown function (DUF1687) Lipoprotein_6 PF01441.14 EDO14790.1 - 0.012 15.4 79.8 1.4 8.7 0.4 14.4 1 1 15 16 16 16 0 Lipoprotein Mod_r PF07200.8 EDO14790.1 - 0.021 14.7 14.8 61 3.4 0.0 7.8 1 1 5 9 9 9 0 Modifier of rudimentary (Mod(r)) protein DUF3829 PF12889.2 EDO14790.1 - 0.04 13.1 10.4 20 4.2 0.1 5.4 2 2 2 4 4 4 0 Protein of unknown function (DUF3829) RTX PF02382.10 EDO14790.1 - 1.8 6.7 28.9 2.5 6.2 1.1 5.0 1 1 3 5 5 5 0 RTX N-terminal domain DASH_Dam1 PF08653.5 EDO14790.1 - 2.1 8.2 27.3 18 5.1 0.2 9.7 4 2 7 11 11 11 0 DASH complex subunit Dam1 Shikimate_DH PF01488.15 EDO14790.1 - 2.5 8.2 21.5 55 3.8 0.2 7.8 1 1 5 7 7 7 0 Shikimate / quinate 5-dehydrogenase Vps5 PF09325.5 EDO14790.1 - 8 5.6 39.8 9.4 5.4 2.6 6.6 1 1 7 8 8 8 0 Vps5 C terminal like MA3 PF02847.12 EDO14791.1 - 0.00037 20.1 29.3 0.072 12.7 2.6 4.2 2 2 3 5 5 5 5 MA3 domain Transglut_i_TM PF14400.1 EDO14791.1 - 1.8 8.0 26.1 2.8 7.4 2.1 4.1 1 1 3 4 4 4 0 Inactive transglutaminase fused to 7 transmembrane helices Cas_Csd1 PF09709.5 EDO14791.1 - 2.7 6.1 42.7 0.23 9.6 6.3 3.2 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_Csd1) PPP5 PF08321.7 EDO14791.1 - 6.2 6.9 44.2 3.7 7.6 2.3 6.1 1 1 5 7 7 7 0 PPP5 TPR repeat region BUD22 PF09073.5 EDO14793.1 - 9.9e-05 21.5 34.9 9.9e-05 21.5 24.2 4.4 1 1 2 3 3 3 1 BUD22 MA3 PF02847.12 EDO14793.1 - 0.061 13.0 12.7 0.83 9.3 1.6 2.3 1 1 1 2 2 2 0 MA3 domain Cas_Csd1 PF09709.5 EDO14793.1 - 0.27 9.5 17.0 1.1 7.4 4.1 2.4 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csd1) Flocculin PF00624.13 EDO14794.1 - 3.7e-166 538.8 605.7 5.9e-15 54.8 9.2 202.9 150 10 44 201 201 201 30 Flocculin repeat Serendipity_A PF05482.7 EDO14794.1 - 4.4 5.6 1.1 4.8e+03 -4.5 0.8 5.3 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) UPF0020 PF01170.13 EDO14795.1 - 1.3e-13 50.9 0.0 2.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EDO14795.1 - 7.9e-09 35.5 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EDO14795.1 - 0.1 12.0 0.0 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Ras PF00071.17 EDO14796.1 - 4.2e-27 94.5 1.9 2.9e-22 78.7 0.1 2.7 2 1 1 3 3 3 2 Ras family Miro PF08477.8 EDO14796.1 - 3.7e-11 43.5 0.1 0.00029 21.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EDO14796.1 - 2.8e-06 26.6 2.3 0.029 13.5 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Arf PF00025.16 EDO14796.1 - 0.00019 20.7 0.3 0.0017 17.6 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Serglycin PF04360.7 EDO14796.1 - 0.005 16.5 0.6 0.011 15.4 0.4 1.6 1 0 0 1 1 1 1 Serglycin AAA_5 PF07728.9 EDO14796.1 - 0.0054 16.4 0.0 0.015 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO14796.1 - 0.012 15.6 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 EDO14796.1 - 0.014 15.1 0.2 0.014 15.1 0.1 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_22 PF13401.1 EDO14796.1 - 0.017 15.2 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EDO14796.1 - 0.057 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EDO14796.1 - 0.33 11.2 6.1 0.98 9.7 0.1 2.6 2 0 0 2 2 2 0 ABC transporter DUF1570 PF07607.6 EDO14796.1 - 1.5 8.7 5.0 6.2 6.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) TRM13 PF05206.9 EDO14797.1 - 2.1e-80 269.7 0.0 2.8e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 EDO14797.1 - 7e-13 47.6 4.2 1.7e-12 46.4 2.9 1.7 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 EDO14797.1 - 3.7e-11 42.4 4.6 4.1e-11 42.3 0.9 2.5 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.1 EDO14797.1 - 1.4e-07 31.3 0.1 2.6e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO14797.1 - 0.067 13.6 0.3 0.46 10.9 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Ldh_1_N PF00056.18 EDO14798.1 - 1.7e-35 121.8 0.7 2.8e-35 121.2 0.5 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EDO14798.1 - 7.3e-28 97.4 0.0 1.3e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 EDO14798.1 - 0.0042 16.4 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase Bax1-I PF01027.15 EDO14799.1 - 3.2e-33 115.0 29.5 8.3e-33 113.7 20.5 1.5 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Prion_bPrPp PF11587.3 EDO14799.1 - 0.84 9.3 3.6 2.7 7.7 2.5 1.9 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal DUF4131 PF13567.1 EDO14799.1 - 3.7 6.9 19.2 0.48 9.8 0.2 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Ribosomal_S11 PF00411.14 EDO14800.1 - 7.1e-06 26.1 0.2 1.5e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 PHD PF00628.24 EDO14801.1 - 0.0027 17.3 1.5 0.0027 17.3 1.0 2.9 3 0 0 3 3 3 1 PHD-finger NTP_transf_2 PF01909.18 EDO14802.1 - 3.1e-16 59.4 2.2 2.6e-15 56.5 0.0 2.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EDO14802.1 - 8.6e-15 54.4 0.4 2.5e-14 52.9 0.0 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase GCR1_C PF12550.3 EDO14803.1 - 6e-26 90.1 0.1 1.1e-25 89.2 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Ribosomal_S19e PF01090.14 EDO14804.1 - 5.6e-54 181.3 0.0 6.2e-54 181.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RRM_1 PF00076.17 EDO14805.1 - 2.3e-37 126.4 1.5 1e-19 69.9 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO14805.1 - 6.3e-33 112.5 0.2 8.7e-16 57.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO14805.1 - 8.2e-14 51.2 0.2 5.3e-06 26.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EDO14805.1 - 0.012 15.1 0.2 4.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain DNA_ligase_aden PF01653.13 EDO14805.1 - 0.019 13.9 0.6 0.019 13.9 0.4 1.8 2 0 0 2 2 2 0 NAD-dependent DNA ligase adenylation domain CCDC84 PF14968.1 EDO14805.1 - 4.1 6.8 16.1 2.7 7.3 3.0 2.1 2 0 0 2 2 2 0 Coiled coil protein 84 RVT_2 PF07727.9 EDO14806.1 - 9.9e-78 260.4 0.0 1.5e-77 259.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO14806.1 - 2.3e-23 82.5 0.1 7.5e-23 80.9 0.1 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDO14806.1 - 2.4e-15 55.9 0.1 1.3e-14 53.5 0.0 2.4 2 0 0 2 2 2 1 GAG-pre-integrase domain eIF3g PF12353.3 EDO14808.1 - 0.13 12.1 5.4 0.41 10.5 2.8 2.2 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G SBF PF01758.11 EDO14813.1 - 5.1e-23 81.4 4.6 1.2e-22 80.2 3.2 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family DUF4137 PF13593.1 EDO14813.1 - 6e-08 32.1 3.3 7.8e-08 31.7 2.3 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) DUF3464 PF11947.3 EDO14813.1 - 0.36 10.2 1.9 0.91 8.9 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3464) DUF3451 PF11933.3 EDO14814.1 - 2.3 7.9 10.3 2.7 7.7 7.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3451) Pkr1 PF08636.5 EDO14815.1 - 3.7e-33 113.4 9.9 4.8e-33 113.0 6.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Claudin_2 PF13903.1 EDO14815.1 - 0.0021 17.7 1.1 0.0024 17.5 0.7 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF2140 PF09911.4 EDO14815.1 - 0.12 11.5 0.7 0.18 10.9 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) DUF3552 PF12072.3 EDO14816.1 - 0.0055 15.9 13.1 0.0055 15.9 9.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) HSP70 PF00012.15 EDO14817.1 - 1.3e-75 254.5 0.1 1.9e-75 254.0 0.1 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO14817.1 - 1.1e-09 37.3 0.0 1.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein PEP-utilizers PF00391.18 EDO14817.1 - 0.1 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain Brix PF04427.13 EDO14818.1 - 1.1e-60 204.5 5.7 1.7e-60 203.9 4.0 1.2 1 0 0 1 1 1 1 Brix domain DUF755 PF05501.6 EDO14818.1 - 1.5 8.9 17.4 0.13 12.2 8.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) FYVE PF01363.16 EDO14819.1 - 2.2e-20 72.3 6.3 2.2e-20 72.3 4.3 3.4 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.1 EDO14819.1 - 6e-10 38.7 19.8 8.4e-10 38.3 1.2 3.6 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EDO14819.1 - 0.002 17.7 1.8 0.002 17.7 1.2 4.8 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO14819.1 - 0.0025 17.8 3.5 0.0025 17.8 2.5 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO14819.1 - 0.0026 17.4 2.9 0.0026 17.4 2.0 3.0 3 0 0 3 3 3 1 RING-type zinc-finger FANCL_C PF11793.3 EDO14819.1 - 0.0046 16.8 2.1 0.0046 16.8 1.4 3.4 5 0 0 5 5 5 1 FANCL C-terminal domain zf-RING_5 PF14634.1 EDO14819.1 - 0.0097 15.6 20.8 0.23 11.1 1.3 4.3 4 0 0 4 4 4 2 zinc-RING finger domain zf-rbx1 PF12678.2 EDO14819.1 - 0.018 15.1 2.3 0.018 15.1 1.6 3.8 2 2 0 3 3 3 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EDO14819.1 - 0.022 14.5 0.3 0.022 14.5 0.2 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger FYVE_2 PF02318.11 EDO14819.1 - 0.33 10.8 12.5 0.27 11.1 5.7 2.6 2 1 0 2 2 2 0 FYVE-type zinc finger PRP21_like_P PF12230.3 EDO14819.1 - 0.65 9.4 6.8 1.9 7.9 4.7 1.7 1 1 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein DUF2175 PF09943.4 EDO14819.1 - 1.3 9.0 5.9 0.48 10.5 1.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) BHD_3 PF10405.4 EDO14820.1 - 4.3e-09 35.9 0.0 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 EDO14820.1 - 1.5e-08 34.7 0.1 5.3e-08 33.0 0.1 2.0 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EDO14820.1 - 7.1e-06 25.4 0.1 2.2e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.10 EDO14820.1 - 0.00023 20.5 0.1 0.00058 19.2 0.0 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain MaoC_dehydratas PF01575.14 EDO14821.1 - 0.031 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 MaoC like domain Methyltransf_23 PF13489.1 EDO14822.1 - 2.8e-19 69.3 0.0 5.6e-19 68.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO14822.1 - 2.9e-15 56.5 0.0 7.8e-15 55.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO14822.1 - 3.1e-13 50.0 0.0 6.5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO14822.1 - 3.2e-13 49.5 0.0 6.9e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO14822.1 - 1.3e-11 44.0 0.0 2.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EDO14822.1 - 6.9e-10 39.4 0.0 5.5e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO14822.1 - 4.5e-09 36.5 0.0 2.3e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO14822.1 - 0.0015 18.5 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 EDO14822.1 - 0.058 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Cyclin PF08613.6 EDO14823.1 - 6.2e-09 36.4 0.7 7.2e-09 36.2 0.5 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EDO14823.1 - 1.6e-06 27.7 1.0 2.2e-06 27.2 0.7 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2119 PF09892.4 EDO14823.1 - 0.07 12.4 0.7 0.092 12.0 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) Scs3p PF10261.4 EDO14824.1 - 2.4e-44 151.1 16.1 5.7e-44 149.9 11.1 1.6 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Orai-1 PF07856.7 EDO14824.1 - 0.0008 19.0 1.2 0.0014 18.2 0.8 1.4 1 0 0 1 1 1 1 Mediator of CRAC channel activity PAP2 PF01569.16 EDO14824.1 - 0.0042 16.7 4.2 0.0042 16.7 2.9 2.0 2 1 1 3 3 3 1 PAP2 superfamily Gly_reductase PF09338.6 EDO14824.1 - 0.028 12.5 0.0 0.04 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase component B subunits DUF843 PF05814.6 EDO14824.1 - 1.1 9.0 12.1 2.5 7.9 0.4 3.5 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) Prenyltrans_2 PF13249.1 EDO14825.1 - 1.8e-32 112.0 0.5 1.2e-15 57.8 0.0 4.8 2 2 3 5 5 5 4 Prenyltransferase-like Prenyltrans PF00432.16 EDO14825.1 - 2.4e-28 97.3 7.2 9.8e-12 44.2 0.8 4.7 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EDO14825.1 - 8.6e-23 80.4 0.0 4.2e-15 55.6 0.0 5.7 3 3 3 6 6 6 5 Prenyltransferase-like Pec_lyase PF09492.5 EDO14825.1 - 0.0047 16.1 0.0 1.3 8.1 0.0 3.5 2 1 1 4 4 4 1 Pectic acid lyase A2M_comp PF07678.9 EDO14825.1 - 0.036 13.2 0.0 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 A-macroglobulin complement component Ubiq-assoc PF09145.5 EDO14826.1 - 8.5e-20 70.3 1.8 9.9e-20 70.1 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin-associated TPR_11 PF13414.1 EDO14826.1 - 6.8e-07 28.8 0.2 0.0039 16.8 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EDO14826.1 - 3e-05 23.4 0.6 0.037 13.6 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat DnaJ PF00226.26 EDO14826.1 - 0.00072 19.2 0.1 0.0022 17.6 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.12 EDO14826.1 - 0.0017 18.0 0.0 0.74 9.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO14826.1 - 0.0019 18.1 0.0 0.17 11.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF963 PF06131.6 EDO14826.1 - 0.0041 16.3 0.9 0.02 14.1 0.6 2.2 1 0 0 1 1 1 1 Schizosaccharomyces pombe repeat of unknown function (DUF963) TPR_7 PF13176.1 EDO14826.1 - 0.0043 16.7 0.1 9.8 6.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO14826.1 - 0.016 15.6 0.2 54 4.5 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDO14826.1 - 0.17 12.6 0.0 34 5.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DASH_Dad4 PF08650.5 EDO14827.1 - 1e-38 131.0 9.2 1.2e-38 130.8 6.4 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 NPV_P10 PF05531.7 EDO14827.1 - 0.0014 18.8 1.7 0.0017 18.5 1.2 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 EDO14827.1 - 0.014 15.1 0.9 0.014 15.1 0.6 1.1 1 0 0 1 1 1 0 Laminin Domain II DASH_Dad3 PF08656.5 EDO14827.1 - 0.038 13.6 0.6 0.05 13.3 0.4 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad3 DUF4047 PF13256.1 EDO14827.1 - 0.052 13.5 1.8 0.15 11.9 1.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) Prominin PF05478.6 EDO14827.1 - 0.056 10.9 1.2 0.055 11.0 0.8 1.0 1 0 0 1 1 1 0 Prominin DASH_Dad1 PF08649.5 EDO14827.1 - 0.065 12.9 4.4 0.14 11.9 3.0 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad1 RasGAP_C PF03836.10 EDO14827.1 - 0.067 12.8 2.2 0.088 12.4 1.5 1.2 1 1 0 1 1 1 0 RasGAP C-terminus FbpA PF05833.6 EDO14827.1 - 0.068 11.6 1.7 0.074 11.5 1.1 1.0 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Spc97_Spc98 PF04130.8 EDO14827.1 - 0.075 11.3 0.3 0.076 11.3 0.2 1.0 1 0 0 1 1 1 0 Spc97 / Spc98 family TMF_TATA_bd PF12325.3 EDO14827.1 - 0.079 12.6 0.8 0.086 12.5 0.6 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Occludin_ELL PF07303.8 EDO14827.1 - 0.086 13.5 0.5 0.096 13.4 0.3 1.2 1 0 0 1 1 1 0 Occludin homology domain DUF4042 PF13251.1 EDO14827.1 - 0.096 12.1 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) BLYB PF05289.6 EDO14827.1 - 0.12 12.1 2.1 0.14 11.9 1.4 1.2 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein DUF3251 PF11622.3 EDO14827.1 - 0.14 11.5 1.4 0.14 11.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) DUF948 PF06103.6 EDO14827.1 - 0.18 11.6 1.6 0.31 10.9 1.1 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.7 EDO14827.1 - 0.21 11.9 2.1 0.24 11.7 0.8 1.6 1 1 0 1 1 1 0 SlyX V-SNARE_C PF12352.3 EDO14827.1 - 0.26 11.4 2.1 0.39 10.8 1.5 1.3 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Oxysterol_BP PF01237.13 EDO14828.1 - 8.3e-104 346.8 1.2 1.9e-103 345.7 0.8 1.6 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 EDO14828.1 - 3.2e-32 110.4 0.8 9.9e-32 108.8 0.5 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EDO14828.1 - 0.00064 19.5 1.5 0.0025 17.6 0.1 2.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EDO14828.1 - 0.0071 16.5 0.4 0.0071 16.5 0.3 3.2 4 0 0 4 4 4 1 Pleckstrin homology domain Rbsn PF11464.3 EDO14829.1 - 0.00032 20.2 1.7 0.00032 20.2 1.2 1.8 2 0 0 2 2 2 1 Rabenosyn Rab binding domain DASH_Dad2 PF08654.5 EDO14829.1 - 0.092 12.7 2.4 4.2 7.4 0.3 3.0 2 2 1 3 3 3 0 DASH complex subunit Dad2 EutA PF06277.6 EDO14829.1 - 0.11 11.0 3.1 0.55 8.7 0.0 2.3 1 1 2 3 3 3 0 Ethanolamine utilisation protein EutA DUF2870 PF11069.3 EDO14829.1 - 0.17 11.9 1.5 6 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) LMBR1 PF04791.11 EDO14829.1 - 1.4 7.3 4.6 2 6.9 3.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MIF4G PF02854.14 EDO14830.1 - 4.5e-44 150.3 47.5 9.9e-22 77.3 3.9 4.2 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 EDO14830.1 - 1.5e-19 70.4 31.7 1.5e-19 70.4 22.0 3.1 2 1 1 3 3 3 1 Up-frameshift suppressor 2 ATP-synt_E PF05680.7 EDO14831.1 - 1.1e-18 66.9 0.2 1.2e-18 66.8 0.2 1.0 1 0 0 1 1 1 1 ATP synthase E chain PBP PF01161.15 EDO14832.1 - 6e-13 48.8 0.2 1e-12 48.1 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PspB PF06667.7 EDO14833.1 - 0.017 15.0 0.4 0.043 13.7 0.0 1.8 2 0 0 2 2 2 0 Phage shock protein B CN_hydrolase PF00795.17 EDO14834.1 - 1.5e-27 96.1 0.0 2.5e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EDO14834.1 - 2.3e-21 75.8 0.0 8.2e-21 74.0 0.0 1.8 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EDO14834.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Asparagine synthase MAGE PF01454.14 EDO14835.1 - 2e-30 105.5 1.4 2.8e-30 105.1 0.9 1.2 1 0 0 1 1 1 1 MAGE family FeoC PF09012.5 EDO14835.1 - 0.068 12.8 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 FeoC like transcriptional regulator IU_nuc_hydro PF01156.14 EDO14836.1 - 2.5e-80 270.0 0.0 2.9e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.17 EDO14837.1 - 3.9e-51 174.0 0.0 4.9e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.7 EDO14838.1 - 6.8e-101 337.2 0.0 1.1e-100 336.5 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein Ribosomal_L13 PF00572.13 EDO14839.1 - 1.4e-42 144.7 0.0 1.8e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 ABC_trans_N PF14510.1 EDO14840.1 - 3.8e-21 74.9 0.1 7.7e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC_tran PF00005.22 EDO14840.1 - 5.2e-18 65.6 0.0 9.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 EDO14840.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cyclin_N PF00134.18 EDO14841.1 - 1.1e-37 128.3 0.4 3.3e-35 120.4 0.1 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDO14841.1 - 8e-20 70.9 0.2 1.7e-19 69.8 0.0 1.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain IF-2B PF01008.12 EDO14842.1 - 1e-84 283.8 0.0 1.3e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family ATP-synt_S1 PF05827.7 EDO14843.1 - 3.8e-05 23.1 0.0 5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) RR_TM4-6 PF06459.7 EDO14843.1 - 0.0092 15.9 7.4 0.013 15.3 5.2 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 BSMAP PF12280.3 EDO14843.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein Mem_trans PF03547.13 EDO14843.1 - 0.012 13.9 0.2 0.017 13.4 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF912 PF06024.7 EDO14843.1 - 0.028 14.4 0.8 0.15 12.1 0.5 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PBP1_TM PF14812.1 EDO14843.1 - 0.1 12.8 6.4 0.19 12.0 4.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.9 EDO14843.1 - 0.21 11.1 13.0 0.35 10.3 9.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Astro_capsid PF03115.9 EDO14843.1 - 0.34 9.1 2.7 0.35 9.0 1.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2457 PF10446.4 EDO14843.1 - 0.49 9.0 17.6 0.65 8.6 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EDO14843.1 - 0.81 7.6 8.9 1 7.2 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein YqfQ PF14181.1 EDO14843.1 - 0.85 9.6 7.3 1.5 8.8 5.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein Nop14 PF04147.7 EDO14843.1 - 0.93 7.3 14.0 1.2 6.9 9.7 1.1 1 0 0 1 1 1 0 Nop14-like family UPF0233 PF06781.7 EDO14843.1 - 0.98 9.0 3.5 1.1 8.9 0.0 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0233) CobT PF06213.7 EDO14843.1 - 1 8.4 11.5 1.4 8.0 8.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1510 PF07423.6 EDO14843.1 - 1.5 8.1 17.5 2.3 7.5 12.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Vfa1 PF08432.5 EDO14843.1 - 3 7.8 16.5 4.9 7.1 11.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 EDO14843.1 - 3.5 6.0 15.2 4.6 5.6 10.5 1.1 1 0 0 1 1 1 0 Daxx Family Viral_Beta_CD PF04530.7 EDO14843.1 - 8.3 6.5 7.9 12 6.0 0.5 3.2 2 2 1 3 3 3 0 Viral Beta C/D like family VMA21 PF09446.5 EDO14844.1 - 8.1e-18 64.1 6.9 1e-17 63.8 4.8 1.1 1 0 0 1 1 1 1 VMA21-like domain DUF3816 PF12822.2 EDO14844.1 - 0.031 14.1 1.7 0.034 14.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) DUF1385 PF07136.6 EDO14844.1 - 0.13 11.2 0.8 0.15 11.0 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) Phage_holin_4 PF05105.7 EDO14844.1 - 0.31 10.7 3.5 0.47 10.1 2.4 1.3 1 1 0 1 1 1 0 Holin family DUF1430 PF07242.6 EDO14844.1 - 0.4 10.7 2.4 0.48 10.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) Pescadillo_N PF06732.6 EDO14845.1 - 1.5e-123 411.5 1.7 1.5e-123 411.5 1.2 2.3 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EDO14845.1 - 1.3e-11 44.5 0.1 6.6e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Orthopox_F14 PF06076.7 EDO14846.1 - 0.009 16.0 2.2 0.85 9.7 0.1 2.3 1 1 0 2 2 2 2 Orthopoxvirus F14 protein Recep_L_domain PF01030.19 EDO14846.1 - 0.052 13.5 0.1 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 Receptor L domain Rhomboid PF01694.17 EDO14847.1 - 3e-28 98.6 18.1 3e-28 98.6 12.5 1.8 2 0 0 2 2 2 1 Rhomboid family RabGAP-TBC PF00566.13 EDO14848.1 - 1e-52 178.7 1.6 3.9e-52 176.8 0.1 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.15 EDO14848.1 - 6.9e-15 54.3 0.1 2e-14 52.8 0.1 1.9 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.1 EDO14848.1 - 9.9e-08 31.2 0.6 0.0005 19.7 0.0 3.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EDO14848.1 - 2.4e-07 30.7 1.9 1.1e-06 28.6 1.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EDO14848.1 - 1.3e-05 24.1 0.2 0.014 14.6 0.0 3.1 2 0 0 2 2 2 2 EF hand BNIP3 PF06553.7 EDO14848.1 - 0.021 14.1 1.2 0.044 13.1 0.2 1.9 2 0 0 2 2 2 0 BNIP3 Telomere_reg-2 PF10193.4 EDO14849.1 - 4.4e-29 101.0 3.4 5.4e-29 100.7 1.1 2.2 2 0 0 2 2 2 1 Telomere length regulation protein Flavin_Reduct PF01613.13 EDO14850.1 - 2.3e-30 105.5 0.0 2.7e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain PH PF00169.24 EDO14851.1 - 1.2e-11 44.7 0.1 7.4e-11 42.1 0.1 2.5 1 1 0 1 1 1 1 PH domain TRAM_LAG1_CLN8 PF03798.11 EDO14852.1 - 2.7e-35 121.7 22.4 2.7e-35 121.7 15.5 1.5 2 0 0 2 2 2 1 TLC domain Gyro_capsid PF04162.7 EDO14852.1 - 0.064 11.4 0.0 0.11 10.7 0.0 1.3 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) CDP-OH_P_transf PF01066.16 EDO14853.1 - 2.9e-19 69.2 2.4 2.9e-19 69.2 1.7 1.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase CBM_21 PF03370.8 EDO14854.1 - 1.5e-27 95.8 12.3 7.8e-27 93.5 8.5 2.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Fungal_trans PF04082.13 EDO14855.1 - 2.2e-13 49.6 4.0 2.2e-13 49.6 2.8 2.7 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO14855.1 - 6.8e-05 22.6 10.8 0.00014 21.6 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH PF00378.15 EDO14856.1 - 1.1e-14 54.1 0.0 1.9e-14 53.4 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Init_tRNA_PT PF04179.7 EDO14856.1 - 0.045 12.6 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase SPA PF08616.5 EDO14856.1 - 0.11 12.1 0.2 0.52 10.0 0.0 2.0 1 1 0 2 2 2 0 Stabilization of polarity axis RF-1 PF00472.15 EDO14857.1 - 4.7e-20 71.4 6.6 7.7e-20 70.7 4.5 1.4 1 0 0 1 1 1 1 RF-1 domain DUF4613 PF15390.1 EDO14857.1 - 0.35 8.9 6.1 0.4 8.8 4.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) DUF2422 PF10337.4 EDO14857.1 - 0.47 9.1 2.5 0.5 9.0 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) IBN_N PF03810.14 EDO14858.1 - 4.8e-15 55.2 0.5 2e-14 53.2 0.2 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EDO14858.1 - 0.0019 18.5 2.0 0.5 10.7 0.1 4.6 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Slx4 PF09494.5 EDO14858.1 - 0.066 12.9 0.1 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 Slx4 endonuclease Utp12 PF04003.7 EDO14859.1 - 9.1e-23 80.2 2.4 1.5e-22 79.5 1.7 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EDO14859.1 - 0.027 14.1 6.5 0.98 9.0 0.3 3.2 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Pribosyltran PF00156.22 EDO14860.1 - 2.8e-10 40.0 0.0 6.2e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain 3Beta_HSD PF01073.14 EDO14860.1 - 0.0074 15.0 0.0 0.0089 14.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Mito_fiss_Elm1 PF06258.6 EDO14860.1 - 0.068 12.1 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Fe-ADH PF00465.14 EDO14860.1 - 0.13 10.8 0.0 0.26 9.8 0.0 1.5 2 0 0 2 2 2 0 Iron-containing alcohol dehydrogenase ISN1 PF06437.6 EDO14861.1 - 1.1e-172 574.3 0.0 1.3e-172 574.0 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase PdxJ PF03740.8 EDO14861.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ CHDCT2 PF08074.6 EDO14862.1 - 1.2 8.8 6.6 1.9 8.2 4.6 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Formyl_trans_N PF00551.14 EDO14863.1 - 1.1e-52 178.1 0.0 1.4e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.13 EDO14863.1 - 0.023 14.3 0.3 0.049 13.2 0.1 1.6 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase PINIT PF14324.1 EDO14864.1 - 6.5e-29 100.8 0.1 1.3e-28 99.9 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EDO14864.1 - 5.9e-20 70.5 5.8 1.2e-19 69.5 4.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EDO14864.1 - 9.2e-06 25.0 0.5 2.7e-05 23.5 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-HIT PF04438.11 EDO14865.1 - 0.0033 17.0 5.3 0.0063 16.1 3.7 1.5 1 0 0 1 1 1 1 HIT zinc finger mIF3 PF14877.1 EDO14865.1 - 0.0084 15.4 0.4 0.014 14.7 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial translation initiation factor Ada3 PF10198.4 EDO14865.1 - 0.087 12.5 1.6 0.1 12.3 0.1 1.8 2 0 0 2 2 2 0 Histone acetyltransferases subunit 3 DER1 PF04511.10 EDO14866.1 - 4.8e-39 133.9 10.2 6e-39 133.5 7.1 1.1 1 0 0 1 1 1 1 Der1-like family Nop25 PF09805.4 EDO14867.1 - 9.7e-33 113.1 34.4 9.7e-33 113.1 23.8 2.8 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) EXS PF03124.9 EDO14868.1 - 3.2e-55 187.5 27.0 3.8e-55 187.3 18.7 1.0 1 0 0 1 1 1 1 EXS family Ribosomal_L2_C PF03947.13 EDO14869.1 - 3.6e-48 162.6 1.6 6.1e-48 161.9 1.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDO14869.1 - 3.5e-27 94.1 0.2 8.2e-27 92.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Peptidase_M28 PF04389.12 EDO14870.1 - 8.1e-27 94.1 0.1 1.2e-26 93.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EDO14870.1 - 5.2e-05 22.8 0.0 7.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ATP-synt_D PF01813.12 EDO14871.1 - 5.9e-66 221.7 4.7 5.9e-66 221.7 3.3 1.4 2 0 0 2 2 2 1 ATP synthase subunit D DUF2201_N PF13203.1 EDO14871.1 - 0.069 12.3 1.4 0.11 11.6 0.9 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Filo_glycop PF01611.11 EDO14871.1 - 0.073 11.8 2.9 0.098 11.4 2.0 1.2 1 0 0 1 1 1 0 Filovirus glycoprotein Siah-Interact_N PF09032.6 EDO14871.1 - 0.31 11.1 7.9 0.11 12.6 3.1 2.0 2 0 0 2 2 2 0 Siah interacting protein, N terminal Sec62 PF03839.11 EDO14871.1 - 0.56 9.5 6.4 0.96 8.8 4.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 IncA PF04156.9 EDO14871.1 - 0.91 9.0 7.4 1.6 8.3 3.2 2.1 2 0 0 2 2 2 0 IncA protein DUF4404 PF14357.1 EDO14871.1 - 3.4 8.1 7.5 6.4 7.2 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) PTPlike_phytase PF14566.1 EDO14871.1 - 4.5 7.3 10.1 1.5 8.8 4.7 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate AFG1_ATPase PF03969.11 EDO14872.1 - 2.8e-74 250.1 0.0 2.3e-68 230.6 0.0 3.2 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EDO14872.1 - 0.00053 20.0 0.4 0.046 13.7 0.3 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO14872.1 - 0.0029 17.7 0.0 0.0094 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EDO14872.1 - 0.0072 16.5 0.1 0.072 13.2 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EDO14872.1 - 0.023 14.8 0.0 0.084 13.0 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 EDO14872.1 - 0.05 13.2 0.0 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase Bac_DnaA PF00308.13 EDO14872.1 - 0.065 12.8 0.6 0.33 10.5 0.1 2.3 2 1 0 2 2 2 0 Bacterial dnaA protein NACHT PF05729.7 EDO14872.1 - 0.093 12.3 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Ribosomal_L11_N PF03946.9 EDO14873.1 - 1.2e-17 63.0 0.6 3.8e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EDO14873.1 - 2.6e-10 40.3 0.5 6.3e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain HSP70 PF00012.15 EDO14874.1 - 5.3e-265 880.0 15.6 6.2e-265 879.7 10.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO14874.1 - 7.1e-15 54.4 3.6 7e-13 47.8 0.7 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EDO14874.1 - 0.00072 19.2 0.1 0.0025 17.4 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF3829 PF12889.2 EDO14874.1 - 0.062 12.4 6.6 0.12 11.5 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF2797 PF10977.3 EDO14874.1 - 0.11 12.0 3.1 0.23 11.0 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) FtsA PF14450.1 EDO14874.1 - 0.14 12.0 12.0 2.9 7.7 1.5 4.4 4 1 0 4 4 4 0 Cell division protein FtsA Hydantoinase_A PF01968.13 EDO14874.1 - 0.81 8.7 10.8 0.21 10.6 0.5 3.4 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase CDT1 PF08839.6 EDO14875.1 - 0.0095 15.8 3.3 0.044 13.7 2.3 2.3 1 1 0 1 1 1 1 DNA replication factor CDT1 like DUF1691 PF07950.6 EDO14876.1 - 9.8e-39 131.6 2.9 1.7e-18 66.5 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) PHD PF00628.24 EDO14877.1 - 1.4e-12 47.1 7.3 1.4e-12 47.1 5.1 1.9 2 0 0 2 2 2 1 PHD-finger DisA-linker PF10635.4 EDO14877.1 - 0.051 13.0 0.6 0.38 10.2 0.1 2.2 2 0 0 2 2 2 0 DisA bacterial checkpoint controller linker region zf-RING_2 PF13639.1 EDO14877.1 - 0.12 12.2 6.2 0.42 10.4 4.3 1.9 1 0 0 1 1 1 0 Ring finger domain Pkinase PF00069.20 EDO14878.1 - 1.2e-66 224.5 0.0 1.7e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO14878.1 - 6.6e-38 130.2 0.0 1e-37 129.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO14878.1 - 1.9e-07 30.3 0.0 3.2e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO14878.1 - 0.005 16.6 0.2 0.038 13.7 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDO14878.1 - 0.066 12.2 0.0 0.13 11.2 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Oxysterol_BP PF01237.13 EDO14879.1 - 3.1e-92 308.7 1.1 3.6e-92 308.5 0.8 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Nop53 PF07767.6 EDO14880.1 - 1e-87 294.6 50.3 1.2e-87 294.4 34.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) PMSI1 PF15322.1 EDO14880.1 - 0.0062 15.6 0.2 0.0062 15.6 0.1 2.8 2 2 1 3 3 3 1 Protein missing in infertile sperm 1, putative DUF2894 PF11445.3 EDO14880.1 - 2.9 8.1 11.4 0.46 10.7 5.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) ABC_tran PF00005.22 EDO14881.1 - 2.8e-11 43.8 0.0 1.4e-10 41.5 0.0 2.1 2 1 0 2 2 2 1 ABC transporter SbcCD_C PF13558.1 EDO14881.1 - 0.0041 16.9 0.2 0.088 12.7 0.1 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 EDO14881.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EDO14881.1 - 0.056 12.8 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain FlxA PF14282.1 EDO14881.1 - 0.081 12.8 0.6 0.12 12.3 0.4 1.2 1 0 0 1 1 1 0 FlxA-like protein APG5 PF04106.7 EDO14882.1 - 2.8e-54 183.6 2.1 3.5e-54 183.2 1.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Pribosyl_synth PF14572.1 EDO14883.1 - 7.9e-41 139.8 2.2 1.8e-35 122.3 1.0 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EDO14883.1 - 4.5e-38 129.5 0.2 2.1e-37 127.3 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EDO14883.1 - 3.4e-11 42.9 0.7 8.8e-11 41.6 0.5 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDO14883.1 - 0.012 14.8 0.1 0.022 13.9 0.1 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 EDO14883.1 - 0.13 12.0 1.1 0.28 10.8 0.8 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C HAD_2 PF13419.1 EDO14884.1 - 7.7e-20 71.8 0.0 1.1e-19 71.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO14884.1 - 5.2e-10 40.0 0.0 6.8e-08 33.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EDO14884.1 - 2.7e-05 24.0 0.0 0.0053 16.6 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDO14884.1 - 0.0082 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EDO14884.1 - 0.037 14.1 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_S10 PF00338.17 EDO14885.1 - 1.2e-26 92.3 1.5 1.4e-26 92.1 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Retrotrans_gag PF03732.12 EDO14885.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 Retrotransposon gag protein Ribosomal_L17 PF01196.14 EDO14885.1 - 0.39 11.3 2.0 0.63 10.6 1.4 1.5 1 1 0 1 1 1 0 Ribosomal protein L17 QRPTase_C PF01729.14 EDO14886.1 - 8.6e-58 194.5 0.0 1e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EDO14886.1 - 5.7e-22 77.3 0.0 1.3e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Chordopox_A15 PF05846.7 EDO14886.1 - 0.041 13.9 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A15 protein IBN_N PF03810.14 EDO14887.1 - 3e-07 30.2 0.0 2.7e-06 27.1 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 EDO14887.1 - 0.035 14.1 0.8 25 5.3 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat DUF656 PF04920.7 EDO14887.1 - 0.047 13.3 0.2 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF656) A_deamin PF02137.13 EDO14888.1 - 1.9e-66 224.7 0.1 2.3e-66 224.4 0.1 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain RAI1 PF08652.6 EDO14889.1 - 3.7e-29 100.3 0.1 7.7e-29 99.2 0.1 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Brr6_like_C_C PF10104.4 EDO14890.1 - 1.1e-44 151.2 5.3 1.3e-44 151.0 3.7 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF2638 PF10937.3 EDO14891.1 - 3.6e-35 121.3 0.0 4.1e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) PDEase_II PF02112.10 EDO14892.1 - 1.8e-59 201.3 0.0 2.5e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EDO14892.1 - 1.4e-08 34.5 0.0 2.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EDO14892.1 - 0.3 10.7 2.5 0.77 9.3 1.8 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Proteasome PF00227.21 EDO14893.1 - 1e-24 86.8 0.2 1.3e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Adap_comp_sub PF00928.16 EDO14894.1 - 2.9e-09 36.4 0.7 4.3e-09 35.8 0.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDO14894.1 - 3.2e-08 33.3 2.0 3.2e-08 33.3 1.4 2.0 2 0 0 2 2 2 1 Clathrin adaptor complex small chain CDC37_N PF03234.9 EDO14894.1 - 0.077 13.3 0.1 0.077 13.3 0.1 2.6 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Dehalogenase PF13486.1 EDO14894.1 - 0.32 10.3 4.9 0.55 9.6 3.4 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit Peptidase_M1 PF01433.15 EDO14895.1 - 3.1e-126 421.6 3.1 1.1e-124 416.4 2.1 2.3 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EDO14895.1 - 2.2e-23 83.0 0.1 4e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EDO14895.1 - 7.7e-15 55.0 0.0 1.8e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Cadherin-like PF12733.2 EDO14897.1 - 0.06 13.6 0.7 0.095 12.9 0.5 1.4 1 1 0 1 1 1 0 Cadherin-like beta sandwich domain Glyco_transf_15 PF01793.11 EDO14898.1 - 2.2e-125 418.0 19.5 3.2e-125 417.4 13.5 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EFP PF01132.15 EDO14898.1 - 0.011 15.4 1.4 0.02 14.5 0.2 2.0 2 0 0 2 2 2 0 Elongation factor P (EF-P) OB domain PhrC_PhrF PF11131.3 EDO14898.1 - 0.12 11.9 0.2 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Rap-phr extracellular signalling Ribosomal_L32e PF01655.13 EDO14898.1 - 0.15 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L32 adh_short PF00106.20 EDO14899.1 - 3.5e-66 222.2 1.8 3.8e-32 111.5 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EDO14899.1 - 5.7e-34 117.3 0.3 1e-15 57.8 0.0 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EDO14899.1 - 3.2e-31 107.2 0.0 6.1e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EDO14899.1 - 6.6e-06 25.9 0.0 0.0001 22.1 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase AdoHcyase_NAD PF00670.16 EDO14899.1 - 0.028 14.2 0.3 0.028 14.2 0.2 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.13 EDO14899.1 - 0.038 13.6 3.5 0.27 10.8 0.1 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 EDO14899.1 - 0.082 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Mito_carr PF00153.22 EDO14900.1 - 1.9e-60 200.5 4.1 3.5e-23 81.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EDO14900.1 - 0.05 13.6 2.0 7.3 6.6 0.0 3.3 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.22 EDO14901.1 - 3.6e-62 206.0 1.1 2.1e-22 78.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIE_alpha PF02002.12 EDO14902.1 - 1.3e-30 105.0 0.0 1.3e-30 105.0 0.0 2.6 3 0 0 3 3 3 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EDO14902.1 - 4.6e-11 41.8 0.4 1.7e-10 40.0 0.3 2.1 1 0 0 1 1 1 1 TFIIB zinc-binding MRP-S33 PF08293.6 EDO14902.1 - 0.0075 16.2 2.3 0.031 14.2 1.6 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Malic_M PF03949.10 EDO14903.1 - 4.2e-79 265.7 0.0 6.8e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EDO14903.1 - 6e-64 214.9 0.0 1e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF3966 PF13110.1 EDO14903.1 - 0.033 13.9 0.1 0.078 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) NIF PF03031.13 EDO14904.1 - 1.2e-49 167.9 0.9 3.4e-49 166.5 0.6 1.8 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF912 PF06024.7 EDO14904.1 - 4.6 7.3 10.5 3.2 7.8 3.6 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Cg6151-P PF10233.4 EDO14905.1 - 2e-36 124.3 14.3 2.3e-36 124.1 9.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF308 PF03729.8 EDO14905.1 - 0.0091 15.9 1.7 0.0091 15.9 1.2 2.7 1 1 2 3 3 3 1 Short repeat of unknown function (DUF308) Chordopox_A13L PF05961.6 EDO14905.1 - 0.068 13.1 0.1 0.068 13.1 0.0 1.9 2 0 0 2 2 2 0 Chordopoxvirus A13L protein gpUL132 PF11359.3 EDO14905.1 - 0.16 11.3 0.2 0.21 10.8 0.1 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 Peptidase_M50B PF13398.1 EDO14905.1 - 0.95 8.8 11.3 0.033 13.5 2.7 1.9 1 1 1 2 2 2 0 Peptidase M50B-like Oxidored_q1_C PF01010.14 EDO14905.1 - 1 8.8 5.1 3.2 7.1 3.5 1.7 1 1 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus DUF3556 PF12077.3 EDO14906.1 - 0.22 9.5 1.3 0.28 9.1 0.9 1.1 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) Pex14_N PF04695.8 EDO14906.1 - 1.1 9.2 5.6 0.67 10.0 1.7 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.4 EDO14906.1 - 6.6 6.1 13.6 11 5.4 4.6 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Period_C PF12114.3 EDO14906.1 - 8.9 5.8 10.2 1.3 8.5 4.3 1.6 2 0 0 2 2 2 0 Period protein 2/3C-terminal region HMG_box PF00505.14 EDO14907.1 - 1.1e-33 115.2 5.7 5.9e-19 68.1 1.4 2.9 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO14907.1 - 5.4e-16 58.7 10.9 4.6e-11 42.9 0.9 3.1 3 0 0 3 3 3 2 HMG-box domain CHDNT PF08073.7 EDO14907.1 - 6.5e-07 28.9 0.0 0.0014 18.2 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain Dapper PF15268.1 EDO14907.1 - 0.42 9.3 45.9 0.53 9.0 31.8 1.0 1 0 0 1 1 1 0 Dapper Cyt-b5 PF00173.23 EDO14908.1 - 5.5e-20 70.9 0.0 1e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Form_Nir_trans PF01226.12 EDO14909.1 - 7.5e-62 208.4 18.7 9.8e-62 208.0 12.9 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Vac14_Fab1_bd PF12755.2 EDO14910.1 - 0.0058 16.9 2.9 1 9.8 0.0 4.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region DUF1571 PF07608.6 EDO14911.1 - 0.0016 17.5 31.7 2.2e+02 0.7 0.0 28.8 57 1 0 58 58 58 0 Protein of unknown function (DUF1571) Pox_A21 PF05323.7 EDO14913.1 - 0.38 11.1 4.2 2.9e+03 -1.4 0.0 8.8 1 1 1 4 4 4 0 Poxvirus A21 Protein PIH1 PF08190.7 EDO14914.1 - 3.2e-16 59.7 2.1 3.8e-16 59.4 1.4 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Zn_clus PF00172.13 EDO14915.1 - 2.1e-07 30.7 5.3 3.6e-07 29.9 3.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HIT PF01230.18 EDO14916.1 - 1.9e-24 86.0 0.5 3.9e-24 85.0 0.1 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EDO14916.1 - 8.3e-09 35.6 0.1 1.4e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF619 PF04768.8 EDO14916.1 - 0.034 13.5 0.1 0.078 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF619) Med21 PF11221.3 EDO14917.1 - 7.7e-48 162.1 4.5 9.5e-48 161.8 3.1 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.5 EDO14917.1 - 0.0045 16.7 0.9 0.0063 16.2 0.6 1.4 1 1 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Med9 PF07544.8 EDO14917.1 - 0.057 13.1 3.6 0.43 10.3 2.5 2.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Glyco_hydro_4 PF02056.11 EDO14917.1 - 0.23 10.7 1.4 0.23 10.7 0.3 1.5 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Phage_T4_gp36 PF03903.8 EDO14918.1 - 0.032 14.3 0.0 0.039 14.0 0.0 1.0 1 0 0 1 1 1 0 Phage T4 tail fibre ApbA_C PF08546.6 EDO14920.1 - 2.9e-31 108.0 0.1 4.4e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EDO14920.1 - 6.3e-30 103.6 0.0 1.1e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EDO14920.1 - 0.019 14.6 0.0 0.04 13.6 0.0 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HSP70 PF00012.15 EDO14921.1 - 2.8e-76 256.7 0.4 2.8e-76 256.7 0.3 1.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO14921.1 - 8.6e-09 34.4 0.0 1.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein PEP-utilizers PF00391.18 EDO14921.1 - 0.072 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain BSD PF03909.12 EDO14922.1 - 3.8e-25 87.3 3.3 1.6e-12 46.9 0.2 2.6 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EDO14922.1 - 2.7e-21 74.9 0.3 8.2e-21 73.4 0.2 1.9 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain FTR_C PF02741.10 EDO14922.1 - 0.17 11.6 1.8 0.28 10.9 0.4 1.9 2 0 0 2 2 2 0 FTR, proximal lobe DEAD PF00270.24 EDO14923.1 - 6.2e-48 162.4 0.0 1.5e-47 161.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO14923.1 - 2.7e-26 91.2 0.0 7.3e-26 89.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO14923.1 - 6.8e-06 26.0 0.3 0.00011 22.0 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit GLTP PF08718.6 EDO14923.1 - 0.1 12.6 0.0 0.53 10.3 0.0 2.2 2 1 0 2 2 2 0 Glycolipid transfer protein (GLTP) Mak16 PF04874.9 EDO14923.1 - 0.92 9.6 12.3 2 8.5 8.5 1.5 1 0 0 1 1 1 0 Mak16 protein C-terminal region Brix PF04427.13 EDO14924.1 - 3.2e-59 199.8 6.3 4.8e-59 199.2 4.4 1.3 1 0 0 1 1 1 1 Brix domain CAF-1_p150 PF11600.3 EDO14924.1 - 0.35 10.2 18.5 0.94 8.8 12.9 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Rotamase_2 PF13145.1 EDO14924.1 - 0.41 11.2 6.1 1.3 9.7 4.2 1.7 1 0 0 1 1 1 0 PPIC-type PPIASE domain Ins_P5_2-kin PF06090.7 EDO14925.1 - 2.9e-51 174.3 6.2 4.2e-51 173.8 4.3 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DS PF01916.12 EDO14926.1 - 1.1e-148 494.2 0.0 1.3e-148 494.0 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase ECR1_N PF14382.1 EDO14927.1 - 1.2e-12 46.9 0.0 2.9e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EDO14927.1 - 0.00076 19.3 0.0 0.0085 16.0 0.0 2.6 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 Met_10 PF02475.11 EDO14928.1 - 2e-78 262.6 0.1 3.7e-78 261.7 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.10 EDO14928.1 - 0.00069 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.11 EDO14928.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.2 EDO14928.1 - 0.02 15.4 0.0 0.068 13.7 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EDO14928.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cyclin PF08613.6 EDO14929.1 - 2.4e-10 41.0 5.3 5.5e-10 39.8 3.7 1.7 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EDO14929.1 - 3.7e-07 29.7 0.5 2.1e-06 27.2 0.3 2.2 1 1 0 1 1 1 1 Cyclin, N-terminal domain BUD22 PF09073.5 EDO14929.1 - 0.0095 15.0 2.8 0.014 14.4 2.0 1.3 1 0 0 1 1 1 1 BUD22 Flocculin PF00624.13 EDO14930.1 - 3.1e-15 55.7 51.1 2.4e-09 36.8 13.6 4.1 4 1 0 4 4 4 2 Flocculin repeat Flocculin PF00624.13 EDO14931.1 - 0 1154.1 1180.6 1e-13 50.8 17.9 163.9 151 2 1 152 152 152 39 Flocculin repeat INCA1 PF15142.1 EDO14932.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 INCA1 GATA PF00320.22 EDO14934.1 - 1.8e-16 59.1 1.9 3.4e-16 58.3 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1690 PF07956.6 EDO14935.1 - 3.9e-43 146.8 3.5 4.4e-43 146.6 2.4 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Matrilin_ccoil PF10393.4 EDO14935.1 - 0.023 14.0 2.4 0.3 10.4 0.1 3.0 2 1 1 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin SecA_SW PF07516.8 EDO14935.1 - 0.037 13.8 0.7 0.05 13.3 0.5 1.1 1 0 0 1 1 1 0 SecA Wing and Scaffold domain CHCH PF06747.8 EDO14935.1 - 0.12 12.3 0.3 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 CHCH domain DUF342 PF03961.8 EDO14935.1 - 0.44 8.8 2.3 0.52 8.6 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pirin PF02678.11 EDO14936.1 - 3.9e-29 100.6 0.1 4.4e-28 97.2 0.1 2.1 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 EDO14936.1 - 4.5e-16 58.7 0.0 3e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EDO14936.1 - 1.2e-05 24.6 0.6 0.00013 21.3 0.3 2.2 2 0 0 2 2 2 1 Cupin domain Ran_BP1 PF00638.13 EDO14937.1 - 5.3e-37 126.5 1.7 6.9e-37 126.2 0.2 2.0 2 0 0 2 2 2 1 RanBP1 domain NUP50 PF08911.6 EDO14937.1 - 2.2e-12 47.1 4.2 2.2e-12 47.1 2.9 4.8 4 2 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) AAA PF00004.24 EDO14938.1 - 4.5e-37 127.1 0.0 9e-37 126.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EDO14938.1 - 5.6e-08 32.7 0.0 2e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO14938.1 - 7.7e-07 29.9 0.1 2.3e-06 28.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO14938.1 - 1.2e-06 28.7 0.1 0.00015 21.7 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EDO14938.1 - 2e-06 27.0 0.1 1.7e-05 24.0 0.0 2.3 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDO14938.1 - 2.9e-06 27.4 0.6 0.00045 20.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EDO14938.1 - 1.5e-05 24.7 0.5 0.00011 21.9 0.1 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 EDO14938.1 - 3e-05 23.7 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial dnaA protein AAA_2 PF07724.9 EDO14938.1 - 3.3e-05 23.8 0.0 9.7e-05 22.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EDO14938.1 - 6.8e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activ_2 PF14532.1 EDO14938.1 - 9.5e-05 22.4 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 EDO14938.1 - 0.00011 22.0 0.0 0.00025 20.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EDO14938.1 - 0.00022 21.5 0.5 0.00055 20.2 0.0 2.1 3 1 0 3 3 1 1 AAA domain IstB_IS21 PF01695.12 EDO14938.1 - 0.00032 20.1 0.1 0.00081 18.8 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EDO14938.1 - 0.00053 20.1 0.1 0.0017 18.5 0.0 1.9 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 EDO14938.1 - 0.00059 19.0 0.2 0.0015 17.7 0.1 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EDO14938.1 - 0.0013 18.4 0.0 0.0025 17.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EDO14938.1 - 0.002 17.0 0.0 0.0046 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EDO14938.1 - 0.0021 17.4 0.7 0.031 13.6 0.1 2.3 1 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EDO14938.1 - 0.0029 17.2 0.1 0.0095 15.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 EDO14938.1 - 0.0036 17.2 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EDO14938.1 - 0.0037 16.8 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EDO14938.1 - 0.0039 15.9 0.0 0.0081 14.8 0.0 1.6 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein ABC_tran PF00005.22 EDO14938.1 - 0.0051 17.1 0.1 0.016 15.5 0.0 2.1 1 1 0 1 1 1 1 ABC transporter TIP49 PF06068.8 EDO14938.1 - 0.008 14.9 0.1 0.019 13.7 0.0 1.5 1 1 0 1 1 1 1 TIP49 C-terminus AAA_10 PF12846.2 EDO14938.1 - 0.0099 15.3 0.5 1.5 8.1 0.0 2.5 1 1 1 2 2 2 1 AAA-like domain Sigma54_activat PF00158.21 EDO14938.1 - 0.012 15.1 0.0 0.042 13.3 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EDO14938.1 - 0.013 15.2 0.8 0.094 12.4 0.0 2.4 1 1 2 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 EDO14938.1 - 0.017 14.8 0.1 0.061 13.0 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_3 PF07726.6 EDO14938.1 - 0.018 14.6 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 EDO14938.1 - 0.025 14.0 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.12 EDO14938.1 - 0.03 13.2 0.0 0.072 11.9 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.13 EDO14938.1 - 0.041 13.4 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 EDO14938.1 - 0.052 12.3 0.0 0.092 11.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain SKI PF01202.17 EDO14938.1 - 0.063 13.1 0.8 0.13 12.1 0.0 1.9 2 0 0 2 2 1 0 Shikimate kinase UPF0079 PF02367.12 EDO14938.1 - 0.067 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EDO14938.1 - 0.09 11.8 0.1 0.97 8.5 0.0 2.3 1 1 1 2 2 2 0 KaiC Evr1_Alr PF04777.8 EDO14939.1 - 2.2e-31 107.5 4.9 2.2e-31 107.5 3.4 1.5 2 0 0 2 2 2 1 Erv1 / Alr family Ndc80_HEC PF03801.8 EDO14939.1 - 0.027 13.9 0.1 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family HTH_OrfB_IS605 PF12323.3 EDO14939.1 - 0.039 13.2 0.0 0.07 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Ribosomal_L10 PF00466.15 EDO14940.1 - 3.8e-27 94.1 0.3 7e-27 93.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EDO14940.1 - 9.1e-20 70.8 7.5 1.9e-19 69.8 2.7 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein DUF2624 PF11116.3 EDO14942.1 - 0.052 14.0 0.4 0.19 12.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) DUF484 PF04340.7 EDO14942.1 - 0.062 12.7 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Abhydrolase_6 PF12697.2 EDO14943.1 - 1.8e-23 83.6 0.0 2.5e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO14943.1 - 1.4e-14 54.2 0.0 2.4e-12 46.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO14943.1 - 2.7e-11 43.4 0.0 4e-11 42.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EDO14943.1 - 5.2e-08 32.7 0.1 1.3e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.15 EDO14943.1 - 0.0036 17.5 0.0 0.0046 17.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 EDO14943.1 - 0.035 13.7 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF3530 PF12048.3 EDO14943.1 - 0.056 12.4 0.0 0.097 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Glucan_synthase PF02364.10 EDO14944.1 - 2e-186 621.3 0.2 3.1e-186 620.7 0.1 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EDO14944.1 - 6.5e-40 135.6 0.1 1.9e-39 134.2 0.1 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Homeobox PF00046.24 EDO14945.1 - 2.9e-14 52.4 0.9 4.7e-14 51.7 0.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EDO14945.1 - 6e-06 25.8 0.4 1.4e-05 24.7 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 EDO14945.1 - 0.0028 16.6 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Flocculin PF00624.13 EDO14946.1 - 3.3e-38 129.2 188.8 5.1e-11 42.2 9.3 187.5 188 0 0 188 188 188 14 Flocculin repeat Fcf1 PF04900.7 EDO14947.1 - 0.027 14.5 0.8 0.034 14.2 0.5 1.2 1 0 0 1 1 1 0 Fcf1 Receptor_2B4 PF11465.3 EDO14947.1 - 0.049 13.5 3.3 0.057 13.3 2.3 1.2 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Baculo_p24 PF05073.7 EDO14947.1 - 0.06 12.9 6.2 0.061 12.8 4.3 1.1 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Toxin_52 PF15605.1 EDO14947.1 - 0.14 12.0 4.3 0.18 11.7 2.9 1.3 1 1 0 1 1 1 0 Putative toxin 52 DUF2660 PF10859.3 EDO14947.1 - 1.1 9.5 7.4 1.5 9.1 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) XhlA PF10779.4 EDO14947.1 - 3.6 7.5 7.6 5.9 6.8 5.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA RP-C_C PF11800.3 EDO14947.1 - 3.8 7.1 5.9 4.4 6.9 4.1 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_C13 PF01650.13 EDO14948.1 - 4e-47 160.6 0.7 6.2e-47 160.0 0.5 1.3 1 0 0 1 1 1 1 Peptidase C13 family ResIII PF04851.10 EDO14949.1 - 1.2e-24 87.1 0.3 1.2e-24 87.1 0.2 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDO14949.1 - 6.4e-15 55.0 1.1 7.5e-14 51.5 0.2 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO14949.1 - 2.9e-13 49.4 0.6 1.2e-12 47.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDO14949.1 - 0.00022 21.3 0.3 0.0016 18.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Cutinase PF01083.17 EDO14949.1 - 0.15 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Cutinase DUF4404 PF14357.1 EDO14949.1 - 0.54 10.7 7.8 0.26 11.7 2.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Brix PF04427.13 EDO14950.1 - 3.2e-43 147.6 3.7 5.7e-43 146.7 2.6 1.4 1 0 0 1 1 1 1 Brix domain DUF3043 PF11241.3 EDO14950.1 - 0.11 12.0 3.6 0.058 12.9 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) V_ATPase_I PF01496.14 EDO14950.1 - 7.3 4.3 9.9 11 3.7 6.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Xpo1 PF08389.7 EDO14951.1 - 0.00043 20.2 10.5 0.072 12.9 0.4 4.0 3 0 0 3 3 3 2 Exportin 1-like protein Herpes_U34 PF04541.8 EDO14951.1 - 0.032 13.1 0.1 0.068 12.0 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus virion protein U34 MMR_HSR1 PF01926.18 EDO14952.1 - 5.7e-15 55.2 0.0 1.2e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDO14952.1 - 5.6e-08 32.1 0.0 1.1e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDO14952.1 - 7.9e-06 25.7 1.0 0.18 11.6 0.7 3.0 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.13 EDO14952.1 - 1.8e-05 24.0 0.0 4.2e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDO14952.1 - 1.9e-05 24.1 0.0 0.00016 21.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EDO14952.1 - 0.0031 16.7 0.0 0.0064 15.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDO14952.1 - 0.0039 16.5 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 Ras family DUF815 PF05673.8 EDO14952.1 - 0.029 13.3 0.0 0.067 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EDO14952.1 - 0.069 13.4 0.2 0.23 11.7 0.0 1.9 1 1 1 2 2 2 0 ABC transporter CFIA_Pcf11 PF11526.3 EDO14952.1 - 0.29 11.3 2.3 0.67 10.1 0.2 2.2 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 MatE PF01554.13 EDO14953.1 - 1.2e-63 213.6 35.8 1e-36 126.0 6.0 2.8 3 0 0 3 3 3 2 MatE Sugar_tr PF00083.19 EDO14954.1 - 3.6e-166 553.2 33.6 4.4e-166 552.9 23.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO14954.1 - 6.1e-28 97.5 39.1 7.4e-23 80.8 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Svf1 PF08622.5 EDO14955.1 - 1e-141 471.6 6.6 1.2e-141 471.3 4.6 1.1 1 0 0 1 1 1 1 Svf1-like Nop14 PF04147.7 EDO14955.1 - 0.0002 19.4 16.8 0.00028 18.9 11.6 1.1 1 0 0 1 1 1 1 Nop14-like family DUF1510 PF07423.6 EDO14955.1 - 0.0029 17.0 11.5 0.0073 15.6 7.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF2457 PF10446.4 EDO14955.1 - 0.0072 15.1 23.0 0.012 14.3 15.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) BUD22 PF09073.5 EDO14955.1 - 0.38 9.7 19.9 0.64 9.0 13.8 1.3 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.5 EDO14955.1 - 0.99 9.3 9.4 2.1 8.3 6.5 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EDO14955.1 - 1.4 6.8 16.2 2.1 6.2 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 EDO14955.1 - 3.5 6.7 13.0 5.6 6.1 9.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RRN3 PF05327.6 EDO14955.1 - 4.7 5.1 9.2 7.9 4.4 6.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cwf_Cwc_15 PF04889.7 EDO14955.1 - 7.9 6.1 20.8 16 5.1 14.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pal1 PF08316.6 EDO14956.1 - 2.5e-56 190.0 2.8 2.5e-56 190.0 1.9 2.7 2 1 0 2 2 2 1 Pal1 cell morphology protein TMEM51 PF15345.1 EDO14956.1 - 2.1 8.0 7.3 2.3 7.8 3.8 1.9 1 1 1 2 2 2 0 Transmembrane protein 51 Sec23_trunk PF04811.10 EDO14957.1 - 1.7e-57 194.5 0.4 2.6e-57 194.0 0.3 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDO14957.1 - 1.2e-17 63.2 0.0 3.8e-17 61.5 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EDO14957.1 - 5.8e-12 44.9 3.6 1.4e-11 43.7 2.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EDO14957.1 - 1.3e-11 44.8 0.3 3.2e-11 43.5 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EDO14957.1 - 3.3e-06 26.6 0.1 8e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.1 EDO14957.1 - 0.0047 17.0 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain MIP PF00230.15 EDO14958.1 - 4.2e-63 212.8 9.1 5.6e-63 212.4 6.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein V-SNARE_C PF12352.3 EDO14959.1 - 5e-15 55.3 5.3 5e-15 55.3 3.7 2.2 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus RseA_N PF03872.8 EDO14959.1 - 0.012 15.8 0.9 0.023 15.0 0.6 1.6 1 1 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain Sec20 PF03908.8 EDO14959.1 - 0.024 14.3 9.4 0.064 12.9 0.4 3.4 1 1 3 4 4 4 0 Sec20 ERp29 PF07749.7 EDO14959.1 - 0.4 11.3 4.8 2.4 8.8 0.1 3.1 1 1 2 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain WXG100 PF06013.7 EDO14959.1 - 0.4 10.7 7.5 17 5.4 0.1 3.7 2 2 0 3 3 3 0 Proteins of 100 residues with WXG TBPIP PF07106.8 EDO14959.1 - 4.9 6.6 13.1 0.14 11.6 2.5 2.4 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-C4H2 PF10146.4 EDO14959.1 - 7.8 6.4 10.8 6.4 6.7 3.4 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein DUF948 PF06103.6 EDO14959.1 - 8.1 6.3 7.2 4.6 7.1 1.3 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Fer2_3 PF13085.1 EDO14960.1 - 1.3e-31 108.7 0.1 2.2e-31 107.9 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EDO14960.1 - 2.1e-10 40.7 7.7 2.1e-10 40.7 5.3 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EDO14960.1 - 7.6e-09 35.4 5.7 7.6e-09 35.4 4.0 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EDO14960.1 - 3.2e-05 24.2 2.7 3.2e-05 24.2 1.9 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EDO14960.1 - 4.4e-05 23.6 5.3 0.035 14.3 0.3 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EDO14960.1 - 7.4e-05 22.4 4.9 7.4e-05 22.4 3.4 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EDO14960.1 - 0.00034 20.2 3.8 0.0048 16.6 0.9 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EDO14960.1 - 0.0013 19.0 5.4 0.0013 19.0 3.7 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 EDO14960.1 - 2.9 8.5 7.7 1.4 9.5 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain DUF1162 PF06650.7 EDO14961.1 - 4.6e-81 272.0 4.2 8.9e-80 267.8 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EDO14961.1 - 3.2e-41 139.5 0.2 1e-40 137.9 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ENTH PF01417.15 EDO14962.1 - 1.3e-35 122.0 1.0 2e-35 121.3 0.7 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EDO14962.1 - 0.0022 16.7 0.2 0.0035 16.0 0.1 1.4 1 0 0 1 1 1 1 ANTH domain SAP18 PF06487.7 EDO14962.1 - 0.055 13.2 0.3 0.19 11.5 0.2 2.2 1 1 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Prp19 PF08606.6 EDO14963.1 - 5.5e-29 99.6 1.5 1.4e-28 98.4 1.0 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 EDO14963.1 - 0.0002 21.2 0.2 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 U-box domain DUF4600 PF15372.1 EDO14963.1 - 0.015 15.5 7.3 0.031 14.4 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) zf-Nse PF11789.3 EDO14963.1 - 0.052 13.0 0.0 0.17 11.4 0.0 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2 PF00096.21 EDO14964.1 - 4.6e-05 23.5 3.1 4.6e-05 23.5 2.2 4.0 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO14964.1 - 0.016 15.4 4.1 0.016 15.4 2.9 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 EDO14964.1 - 0.017 15.3 2.8 0.019 15.1 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type P22_Tail-4 PF11650.3 EDO14965.1 - 0.033 13.7 0.2 0.077 12.5 0.1 1.6 1 0 0 1 1 1 0 P22 tail accessory factor Erf4 PF10256.4 EDO14965.1 - 8.3 6.3 13.7 15 5.4 0.3 4.6 3 1 1 4 4 4 0 Golgin subfamily A member 7/ERF4 family Pab87_oct PF13969.1 EDO14966.1 - 0.032 14.3 0.1 0.059 13.4 0.1 1.5 1 0 0 1 1 1 0 Pab87 octamerisation domain KH_1 PF00013.24 EDO14967.1 - 2.1e-10 40.0 0.0 8.3e-05 22.1 0.0 4.3 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 EDO14967.1 - 2.6e-07 30.1 0.1 0.0031 17.1 0.0 4.3 4 0 0 4 4 4 2 KH domain RasGEF PF00617.14 EDO14968.1 - 1.1e-60 204.6 3.1 1.9e-60 203.8 0.6 2.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EDO14968.1 - 1e-18 67.3 0.4 1e-18 67.3 0.2 5.6 4 1 0 4 4 4 1 RasGEF N-terminal motif SH3_9 PF14604.1 EDO14968.1 - 2.6e-09 36.5 0.0 5.9e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDO14968.1 - 2.6e-08 33.1 0.5 8.1e-08 31.5 0.3 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EDO14968.1 - 1.4e-07 30.9 0.1 3.4e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PD40 PF07676.7 EDO14968.1 - 0.084 12.5 0.1 0.084 12.5 0.1 2.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat UQ_con PF00179.21 EDO14969.1 - 3.7e-34 117.1 0.0 4.8e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EDO14969.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EDO14969.1 - 0.043 13.7 0.2 0.076 12.9 0.1 1.5 1 1 0 1 1 1 0 RWD domain PI3_PI4_kinase PF00454.22 EDO14970.1 - 1.5e-44 152.2 0.0 5.1e-44 150.4 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EDO14970.1 - 3.2e-27 94.8 0.1 8.6e-27 93.5 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Syntaxin-6_N PF09177.6 EDO14971.1 - 7.9 6.9 7.4 6 7.3 1.1 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal RVT_2 PF07727.9 EDO14972.1 - 1.8e-41 141.7 0.6 4.4e-41 140.4 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO14972.1 - 3.6e-14 52.9 0.0 9.4e-14 51.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RNase_H PF00075.19 EDO14972.1 - 0.00012 22.4 3.0 0.00014 22.1 0.0 2.7 3 0 0 3 3 3 1 RNase H gag_pre-integrs PF13976.1 EDO14972.1 - 0.001 18.6 0.1 0.0029 17.2 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain FA_hydroxylase PF04116.8 EDO14973.1 - 6.7e-15 55.4 23.6 6.7e-15 55.4 16.4 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily FDC-SP PF15215.1 EDO14973.1 - 0.013 15.7 0.6 0.013 15.7 0.4 2.1 2 0 0 2 2 2 0 Follicular dendritic cell secreted peptide NTP_transferase PF00483.18 EDO14974.1 - 5.1e-49 166.8 0.0 6.9e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EDO14974.1 - 1.4e-10 40.2 7.8 1.9e-07 30.2 1.2 4.0 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EDO14974.1 - 2e-10 40.9 0.0 2.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EDO14974.1 - 0.014 14.9 1.0 0.014 14.9 0.7 3.2 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 EDO14974.1 - 0.046 13.3 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase DUF4149 PF13664.1 EDO14975.1 - 6.2e-05 22.9 0.3 0.00018 21.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) ETRAMP PF09716.5 EDO14975.1 - 0.12 12.3 1.0 0.15 11.9 0.7 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MAS20 PF02064.10 EDO14976.1 - 1.4e-17 63.7 1.5 1.3e-16 60.6 1.0 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor PsbN PF02468.10 EDO14976.1 - 0.0095 15.5 1.0 0.019 14.5 0.7 1.4 1 0 0 1 1 1 1 Photosystem II reaction centre N protein (psbN) MFS_Mycoplasma PF07672.8 EDO14976.1 - 0.055 12.6 0.1 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter DcuA_DcuB PF03605.9 EDO14976.1 - 0.14 10.9 0.3 0.24 10.2 0.1 1.5 1 1 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF3818 PF12825.2 EDO14977.1 - 1.1e-133 445.0 13.8 1.1e-133 445.0 9.6 1.8 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EDO14977.1 - 1.6e-45 154.0 1.6 1.6e-45 154.0 1.1 2.2 2 0 0 2 2 2 1 PX-associated PX PF00787.19 EDO14977.1 - 1e-11 44.6 1.2 5.5e-11 42.2 0.1 2.9 2 1 0 2 2 2 1 PX domain DUF1689 PF07954.6 EDO14978.1 - 4.4e-58 195.4 0.2 6.2e-58 194.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) DHO_dh PF01180.16 EDO14979.1 - 3.2e-97 325.0 0.1 3.9e-97 324.7 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EDO14979.1 - 0.003 16.4 0.0 0.14 10.9 0.0 2.4 2 1 0 2 2 2 2 FMN-dependent dehydrogenase DUF3657 PF12394.3 EDO14979.1 - 0.013 15.5 0.7 0.034 14.2 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3657) Dimer_Tnp_hAT PF05699.9 EDO14980.1 - 0.00014 21.4 0.1 0.00048 19.6 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region BING4CT PF08149.6 EDO14981.1 - 1.6e-37 126.8 0.0 3.5e-36 122.5 0.0 2.8 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 EDO14981.1 - 1.2e-08 34.5 0.0 1.2e-06 28.1 0.0 3.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Nup160 PF11715.3 EDO14981.1 - 0.0085 14.2 0.0 0.014 13.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 PC_rep PF01851.17 EDO14982.1 - 8.5e-42 139.0 24.6 2.2e-05 24.4 0.0 10.3 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EDO14982.1 - 1.7e-15 57.0 7.2 4.8e-14 52.4 0.1 4.1 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.17 EDO14982.1 - 2e-08 33.6 2.1 0.29 11.3 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EDO14982.1 - 9.2e-08 32.3 4.6 0.057 13.9 0.0 5.1 3 2 2 5 5 5 2 HEAT-like repeat DUF3549 PF12069.3 EDO14982.1 - 0.0052 15.6 2.1 0.012 14.4 1.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3549) PI-PLC-Y PF00387.14 EDO14982.1 - 0.0078 16.1 1.2 0.017 15.0 0.1 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain RICTOR_V PF14668.1 EDO14982.1 - 0.022 14.7 0.2 0.23 11.4 0.0 2.9 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.18 EDO14982.1 - 0.052 13.3 0.5 26 4.8 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Vfa1 PF08432.5 EDO14982.1 - 2.5 8.0 15.6 4.4 7.2 10.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TPR_2 PF07719.12 EDO14982.1 - 4.9 7.3 5.4 8.4 6.5 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.14 EDO14983.1 - 3.6e-52 176.0 0.1 7.8e-52 174.9 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDO14983.1 - 1e-34 118.8 0.1 1.4e-34 118.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDO14983.1 - 5.7e-06 26.2 0.2 1.4e-05 24.9 0.2 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EDO14983.1 - 5.6e-05 23.0 0.1 0.00013 21.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 EDO14983.1 - 0.0014 18.0 0.0 0.0045 16.4 0.0 2.0 1 0 0 1 1 1 1 ACT domain IlvN PF07991.7 EDO14983.1 - 0.0042 16.4 0.1 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EDO14983.1 - 0.05 13.2 0.4 0.29 10.7 0.3 2.2 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EDO14983.1 - 0.073 12.4 0.2 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.1 EDO14983.1 - 0.11 12.7 0.0 0.63 10.3 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain APH PF01636.18 EDO14984.1 - 4.1e-08 33.2 0.0 3.4e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EDO14984.1 - 0.021 13.8 0.0 0.042 12.8 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Kdo PF06293.9 EDO14984.1 - 0.025 13.6 0.0 5.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PCI PF01399.22 EDO14985.1 - 0.00028 21.1 0.5 0.0011 19.2 0.3 2.1 1 0 0 1 1 1 1 PCI domain PPR_2 PF13041.1 EDO14986.1 - 2.3e-17 62.7 0.0 9.7e-12 44.6 0.0 3.3 2 0 0 2 2 2 2 PPR repeat family DUF668 PF05003.7 EDO14986.1 - 0.088 13.0 0.8 0.25 11.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF668) MAM33 PF02330.11 EDO14987.1 - 8e-49 166.1 15.4 9.9e-49 165.8 10.7 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cons_hypoth95 PF03602.10 EDO14987.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Apc9 PF12856.2 EDO14987.1 - 0.35 10.9 5.8 0.82 9.7 4.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 9 HMG_box PF00505.14 EDO14988.1 - 9.4e-25 86.6 0.3 1.5e-24 86.0 0.2 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO14988.1 - 1.1e-17 64.1 0.3 1.6e-17 63.6 0.2 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EDO14988.1 - 0.0051 16.5 1.8 0.0067 16.2 1.0 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.7 EDO14988.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.8 EDO14988.1 - 0.026 14.7 0.1 0.032 14.4 0.1 1.2 1 0 0 1 1 1 0 YABBY protein zf-Tim10_DDP PF02953.10 EDO14989.1 - 3.7e-16 58.1 0.2 4.7e-16 57.8 0.2 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TTL PF03133.10 EDO14990.1 - 1.3e-78 263.8 5.0 2.5e-78 262.9 3.4 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EDO14990.1 - 8.2e-40 136.2 0.0 1.6e-39 135.2 0.0 1.5 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 EDO14990.1 - 2.7e-05 23.1 0.0 0.019 13.7 0.0 3.0 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EDO14990.1 - 0.0029 17.3 0.0 0.0079 15.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Nro1 PF12753.2 EDO14990.1 - 0.0044 16.0 1.5 0.0079 15.1 1.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 ATPgrasp_Ter PF15632.1 EDO14990.1 - 0.014 14.1 0.0 0.032 12.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon RXT2_N PF08595.6 EDO14991.1 - 2.7e-43 147.3 2.0 2.7e-43 147.3 1.4 2.6 3 0 0 3 3 3 1 RXT2-like, N-terminal LEDGF PF11467.3 EDO14991.1 - 0.028 14.0 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Pkinase PF00069.20 EDO14992.1 - 7.6e-62 208.8 0.2 3.5e-61 206.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO14992.1 - 2.9e-29 101.9 0.0 4.1e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sec8_exocyst PF04048.9 EDO14993.1 - 3.9e-50 169.1 11.0 2.8e-49 166.4 3.3 3.2 2 0 0 2 2 2 2 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EDO14993.1 - 2.5e-06 26.6 6.5 3.6e-06 26.1 3.3 2.3 1 1 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) ERCC4 PF02732.10 EDO14994.1 - 5.2e-07 29.5 2.9 1.3e-06 28.2 0.6 2.6 2 0 0 2 2 2 1 ERCC4 domain DUF1465 PF07323.7 EDO14994.1 - 0.04 13.4 0.3 0.13 11.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) Fes1 PF08609.5 EDO14995.1 - 5.5e-28 97.2 1.2 5.5e-28 97.2 0.9 2.2 2 1 1 3 3 3 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EDO14995.1 - 0.00047 20.3 0.1 0.003 17.7 0.0 2.4 1 1 1 2 2 2 1 HEAT repeats IBN_N PF03810.14 EDO14995.1 - 0.0018 18.1 0.6 0.017 14.9 0.0 2.7 2 2 0 2 2 2 1 Importin-beta N-terminal domain DUF3361 PF11841.3 EDO14995.1 - 0.0028 17.3 1.8 0.0044 16.7 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) DUF2454 PF10521.4 EDO14995.1 - 0.0049 15.9 1.0 0.018 14.0 0.2 1.9 1 1 0 2 2 2 1 Protein of unknown function (DUF2454) RIX1 PF08167.7 EDO14995.1 - 0.0083 15.8 0.6 0.038 13.6 0.0 2.1 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis HEAT PF02985.17 EDO14995.1 - 0.018 15.0 0.0 3.1 8.1 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 EDO14995.1 - 0.022 15.2 0.1 0.32 11.5 0.0 2.8 2 1 1 3 3 3 0 HEAT-like repeat Arm PF00514.18 EDO14995.1 - 0.1 12.4 0.2 7.1 6.6 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SIP1 PF04938.7 EDO14996.1 - 2.4e-06 27.0 0.3 2.2e-05 23.9 0.1 2.4 2 1 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Mito_carr PF00153.22 EDO14997.1 - 8.8e-59 195.2 2.6 9.4e-20 70.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CM_2 PF01817.16 EDO14998.1 - 2e-14 53.4 0.1 1.6e-07 31.2 0.0 3.9 3 1 0 3 3 3 2 Chorismate mutase type II DnaJ PF00226.26 EDO14999.1 - 2.6e-15 55.9 1.8 4.1e-15 55.2 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain EF-hand_1 PF00036.27 EDO15001.1 - 1.5e-30 102.1 3.0 1.7e-08 33.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EDO15001.1 - 1.3e-27 95.6 0.3 6.8e-14 51.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDO15001.1 - 5.8e-26 88.0 2.0 6.3e-08 31.8 0.0 4.3 4 1 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EDO15001.1 - 2e-20 71.1 2.7 1.9e-07 30.1 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EDO15001.1 - 5.3e-19 67.5 4.5 8.4e-08 31.7 0.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EDO15001.1 - 4e-12 45.8 0.0 2.2e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EDO15001.1 - 3.9e-06 26.8 0.1 0.0013 18.7 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EDO15001.1 - 1.2e-05 24.7 0.0 0.13 11.8 0.0 2.8 2 1 0 3 3 3 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 EDO15001.1 - 0.00046 19.7 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 2 Caleosin related protein DUF853 PF05872.7 EDO15001.1 - 0.0043 15.4 0.2 0.1 10.9 0.0 2.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF853) TerB PF05099.8 EDO15001.1 - 0.008 15.9 0.1 0.33 10.6 0.0 2.2 2 1 0 2 2 2 1 Tellurite resistance protein TerB EF-hand_4 PF12763.2 EDO15001.1 - 0.012 15.3 0.3 0.026 14.2 0.1 1.7 1 1 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand LNS2 PF08235.8 EDO15001.1 - 0.016 14.8 0.0 0.71 9.4 0.0 2.1 1 1 1 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) ERAP1_C PF11838.3 EDO15001.1 - 0.019 14.1 0.2 0.027 13.7 0.1 1.3 1 1 0 1 1 1 0 ERAP1-like C-terminal domain RNA_pol_Rpb4 PF03874.11 EDO15001.1 - 0.16 12.0 0.8 1.4 8.9 0.0 2.4 2 1 0 2 2 2 0 RNA polymerase Rpb4 Hist_deacetyl PF00850.14 EDO15002.1 - 4.3e-77 259.4 0.0 9.7e-77 258.2 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain Med1 PF10744.4 EDO15003.1 - 5.6e-89 298.6 14.2 5.6e-89 298.6 9.8 1.5 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 DUF2745 PF10922.3 EDO15003.1 - 0.036 13.9 0.0 0.16 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2745) NUDIX PF00293.23 EDO15004.1 - 4.1e-16 58.8 0.0 8.3e-16 57.8 0.0 1.4 2 0 0 2 2 2 1 NUDIX domain EnY2 PF10163.4 EDO15005.1 - 4.4e-07 29.7 0.1 4.6e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor e(y)2 ATP-synt_E_2 PF08112.6 EDO15005.1 - 0.063 13.3 0.3 0.083 12.9 0.2 1.2 1 0 0 1 1 1 0 ATP synthase epsilon subunit HC2 PF07382.6 EDO15006.1 - 0.00054 19.8 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 RRM_1 PF00076.17 EDO15007.1 - 1.2e-17 63.3 0.0 3.2e-15 55.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO15007.1 - 3e-07 30.3 0.0 1.7e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) YjeF_N PF03853.10 EDO15009.1 - 2.6e-38 131.2 0.0 3.1e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SMK-1 PF04802.10 EDO15010.1 - 6.4e-61 205.2 11.8 9.2e-61 204.7 6.9 2.3 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 ArfGap PF01412.13 EDO15011.1 - 8e-34 115.9 0.0 1.7e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Rtt106 PF08512.7 EDO15012.1 - 2.5e-25 88.2 3.0 2.8e-25 88.1 0.5 2.2 2 1 0 2 2 2 1 Histone chaperone Rttp106-like PulS_OutS PF09691.5 EDO15012.1 - 0.016 15.2 0.6 0.033 14.1 0.4 1.4 1 0 0 1 1 1 0 Bacterial chaperone lipoprotein (PulS_OutS) DUF2796 PF10986.3 EDO15012.1 - 7.2 6.5 16.2 13 5.7 11.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) RIO1 PF01163.17 EDO15013.1 - 1.6e-41 141.7 0.6 2.3e-41 141.2 0.4 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EDO15013.1 - 3.7e-32 110.2 0.1 7.9e-32 109.1 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EDO15013.1 - 1.8e-05 24.6 0.2 0.23 11.1 0.4 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDO15013.1 - 0.0011 18.0 0.1 0.088 11.8 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2413 PF10310.4 EDO15013.1 - 0.11 11.3 2.4 7.7 5.2 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Cwf_Cwc_15 PF04889.7 EDO15013.1 - 0.93 9.1 7.9 1.4 8.5 5.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EDO15013.1 - 5.1 5.0 8.3 7.6 4.4 5.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Rick_17kDa_Anti PF05433.10 EDO15014.1 - 3.1e-08 33.1 6.0 4.7e-08 32.5 4.2 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EDO15014.1 - 6.5e-06 25.6 3.7 1.2e-05 24.8 2.6 1.5 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_OmpA PF13436.1 EDO15014.1 - 0.0071 16.0 10.8 0.016 14.8 7.4 1.7 1 1 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain PRCC PF10253.4 EDO15014.1 - 0.01 16.5 5.0 0.012 16.2 3.5 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2076 PF09849.4 EDO15014.1 - 0.027 14.5 21.6 0.38 10.7 15.0 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Trep_Strep PF09605.5 EDO15014.1 - 0.14 11.7 1.3 0.29 10.7 0.1 1.8 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF1183 PF06682.7 EDO15014.1 - 1.2 8.6 18.5 1.9 8.0 12.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Pex14_N PF04695.8 EDO15014.1 - 2.3 8.2 15.7 2.5 8.1 10.3 1.6 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4175 PF13779.1 EDO15014.1 - 4.9 4.7 12.1 5 4.6 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Gly-zipper_YMGG PF13441.1 EDO15014.1 - 5.5 6.5 15.9 3.7 7.1 2.6 2.1 1 1 2 3 3 3 0 YMGG-like Gly-zipper Shisa PF13908.1 EDO15014.1 - 9.3 6.3 10.6 18 5.4 7.3 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Aldo_ket_red PF00248.16 EDO15015.1 - 6e-61 205.7 0.0 6.8e-61 205.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Flocculin PF00624.13 EDO15016.1 - 6.5e-10 38.6 51.5 1.1e-07 31.5 17.8 4.6 5 1 0 5 5 5 2 Flocculin repeat Flocculin PF00624.13 EDO15017.1 - 8.9e-19 67.0 53.2 8e-14 51.1 19.4 6.3 7 1 0 8 8 8 2 Flocculin repeat Exo_endo_phos PF03372.18 EDO15018.1 - 2.5e-16 60.3 0.0 3.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EDO15018.1 - 1.6e-11 43.8 0.1 2.1e-10 40.2 0.1 2.3 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EDO15018.1 - 5.7e-10 38.9 0.5 1.5e-09 37.6 0.3 1.8 1 0 0 1 1 1 1 GRF zinc finger Rft-1 PF04506.8 EDO15019.1 - 9.6e-174 578.7 46.3 1.1e-173 578.5 32.1 1.0 1 0 0 1 1 1 1 Rft protein DUF2061 PF09834.4 EDO15019.1 - 0.098 12.8 6.5 0.23 11.6 0.2 3.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) Phlebovirus_G2 PF07245.6 EDO15019.1 - 0.15 10.3 1.9 0.093 10.9 0.1 1.5 2 0 0 2 2 2 0 Phlebovirus glycoprotein G2 CBFD_NFYB_HMF PF00808.18 EDO15020.1 - 3.4e-25 87.8 0.1 5.4e-25 87.2 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDO15020.1 - 7.7e-07 29.1 0.0 1.3e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAN_3 PF08277.7 EDO15020.1 - 0.02 14.5 0.5 0.03 13.9 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain TFIID_20kDa PF03847.8 EDO15020.1 - 0.046 14.0 0.1 0.089 13.0 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.8 EDO15020.1 - 0.062 13.0 0.0 0.45 10.2 0.0 2.2 2 1 0 2 2 2 0 Bromodomain associated SAM_PNT PF02198.11 EDO15020.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain LON PF02190.11 EDO15021.1 - 6.1e-21 75.0 0.6 1.2e-20 74.0 0.4 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain Lon_C PF05362.8 EDO15022.1 - 8e-66 221.2 0.0 2.1e-65 219.8 0.0 1.7 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EDO15022.1 - 4.8e-23 81.8 0.0 1.4e-22 80.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EDO15022.1 - 2e-07 31.1 0.0 8.7e-07 29.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 EDO15022.1 - 2.1e-06 27.2 0.0 4.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_17 PF13207.1 EDO15022.1 - 1.1e-05 26.1 0.6 0.0001 23.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDO15022.1 - 2.1e-05 24.6 0.1 0.0013 18.9 0.0 2.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDO15022.1 - 3.1e-05 23.7 0.0 0.00011 21.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EDO15022.1 - 8.3e-05 21.7 0.0 0.0022 17.0 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 EDO15022.1 - 0.00018 20.2 0.0 0.00044 19.0 0.0 1.5 1 0 0 1 1 1 1 PrkA AAA domain AAA_14 PF13173.1 EDO15022.1 - 0.00028 20.7 0.1 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EDO15022.1 - 0.00038 19.2 0.2 0.043 12.5 0.0 2.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_16 PF13191.1 EDO15022.1 - 0.00064 19.7 0.1 0.0028 17.6 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.1 EDO15022.1 - 0.0046 17.2 0.1 0.0046 17.2 0.0 3.3 5 0 0 5 5 3 1 AAA domain ClpB_D2-small PF10431.4 EDO15022.1 - 0.007 16.2 0.0 0.028 14.3 0.0 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein RNA_helicase PF00910.17 EDO15022.1 - 0.017 15.3 0.1 0.071 13.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase SKI PF01202.17 EDO15022.1 - 0.018 14.9 0.0 0.059 13.2 0.0 1.9 1 0 0 1 1 1 0 Shikimate kinase DUF258 PF03193.11 EDO15022.1 - 0.022 13.9 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EDO15022.1 - 0.025 13.9 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 EDO15022.1 - 0.039 13.4 0.0 0.094 12.2 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EDO15022.1 - 0.054 13.0 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EDO15022.1 - 0.056 13.1 0.4 0.92 9.1 0.1 2.5 1 1 1 2 2 2 0 NTPase ATP-synt_ab PF00006.20 EDO15022.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EDO15022.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDO15022.1 - 0.17 12.2 1.2 0.41 10.9 0.1 2.2 2 0 0 2 2 1 0 ABC transporter zf-UBR PF02207.15 EDO15023.1 - 1.1e-13 50.6 9.3 1.1e-13 50.6 6.5 2.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) zf-AD PF07776.10 EDO15023.1 - 0.018 15.0 0.0 0.018 15.0 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) DUF4428 PF14471.1 EDO15023.1 - 0.066 12.9 0.1 0.066 12.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) MCM PF00493.18 EDO15024.1 - 3.4e-142 473.1 0.2 5e-142 472.5 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EDO15024.1 - 4.8e-30 104.6 33.5 4.8e-30 104.6 23.2 3.9 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EDO15024.1 - 6.7e-14 52.4 0.0 1.8e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDO15024.1 - 2.6e-09 36.5 0.0 2.3e-07 30.2 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDO15024.1 - 2.8e-07 30.3 0.0 5.9e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EDO15024.1 - 0.00081 18.9 0.0 0.0071 15.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDO15024.1 - 0.0015 18.0 0.1 0.0095 15.4 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 EDO15024.1 - 0.018 15.2 0.0 0.056 13.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L18e PF00828.14 EDO15025.1 - 7.4e-21 74.8 1.9 9.7e-21 74.4 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 DEAD PF00270.24 EDO15026.1 - 2.9e-42 144.0 1.4 7.2e-41 139.4 0.3 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO15026.1 - 3e-24 84.6 0.2 7e-24 83.4 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO15026.1 - 1.4e-05 25.0 1.3 4.7e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC4 PF02732.10 EDO15027.1 - 1.1e-25 90.1 0.1 3.2e-25 88.5 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain Dala_Dala_lig_C PF07478.8 EDO15027.1 - 0.03 13.6 1.9 4.2 6.7 0.2 2.7 3 0 0 3 3 3 0 D-ala D-ala ligase C-terminus MTHFR PF02219.12 EDO15028.1 - 1.9e-110 368.5 0.0 2.4e-110 368.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase IGR PF09597.5 EDO15029.1 - 0.0024 17.7 0.9 0.0045 16.8 0.3 1.7 2 0 0 2 2 2 1 IGR protein motif Spo7_2_N PF15407.1 EDO15029.1 - 0.031 13.7 0.0 0.094 12.1 0.0 1.8 1 0 0 1 1 1 0 Sporulation protein family 7 DUF1767 PF08585.7 EDO15029.1 - 0.059 13.6 0.1 0.25 11.6 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1767) Sybindin PF04099.7 EDO15030.1 - 2.7e-37 127.6 6.5 1.6e-15 57.0 0.4 3.2 3 0 0 3 3 3 3 Sybindin-like family Sedlin_N PF04628.8 EDO15030.1 - 3.4e-08 33.4 3.0 4.1e-08 33.1 0.5 2.0 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Thiolase_N PF00108.18 EDO15031.1 - 2.9e-100 334.6 1.4 3.8e-100 334.2 0.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDO15031.1 - 1.1e-45 154.0 0.3 2.8e-45 152.7 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EDO15031.1 - 2.2e-05 24.0 0.3 4.2e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EDO15031.1 - 0.065 12.8 0.9 1.2 8.9 0.1 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AdoMet_MTase PF07757.8 EDO15032.1 - 1.8e-41 140.7 0.2 3.1e-41 139.9 0.1 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.1 EDO15032.1 - 0.0013 18.2 0.2 0.0029 17.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EDO15032.1 - 0.044 13.1 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.1 EDO15032.1 - 0.073 12.7 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EDO15032.1 - 0.12 12.0 0.1 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EDO15032.1 - 0.12 12.9 0.0 0.45 11.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EDO15033.1 - 3.1e-76 255.9 0.0 3.6e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15033.1 - 7.8e-38 130.0 0.0 1.1e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO15033.1 - 0.0038 16.2 0.0 0.0081 15.1 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EDO15033.1 - 0.054 13.2 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Apc4 PF12896.2 EDO15034.1 - 2.3e-25 89.1 0.1 3.7e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 SUI1 PF01253.17 EDO15035.1 - 4.5e-14 52.0 0.4 2e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor SUI1 Kin17_mid PF10357.4 EDO15035.1 - 0.001 18.6 0.5 0.0028 17.2 0.3 1.7 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein SWIB PF02201.13 EDO15035.1 - 0.0071 16.0 0.4 0.017 14.8 0.3 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Ribosomal_L1 PF00687.16 EDO15036.1 - 2.7e-25 89.0 0.6 3.3e-25 88.7 0.2 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family PHAT PF09246.5 EDO15037.1 - 0.0041 16.7 0.6 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 PHAT Aminotran_1_2 PF00155.16 EDO15038.1 - 6.8e-39 133.8 0.0 9.8e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EDO15038.1 - 0.00069 18.8 0.0 0.0017 17.5 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase rve PF00665.21 EDO15039.1 - 0.0095 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain SMC_N PF02463.14 EDO15041.1 - 1.5e-63 213.9 66.9 2.1e-62 210.2 46.4 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDO15041.1 - 3.5e-25 88.2 0.1 2.5e-24 85.5 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EDO15041.1 - 6.1e-08 33.2 24.6 6.1e-08 33.2 17.1 7.3 3 2 3 6 6 6 1 AAA domain AAA_21 PF13304.1 EDO15041.1 - 6.1e-08 32.9 1.1 6.1e-08 32.9 0.8 6.2 2 2 3 5 5 5 2 AAA domain AAA_29 PF13555.1 EDO15041.1 - 0.00043 19.7 0.0 0.00084 18.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Herpes_ICP4_N PF03584.10 EDO15041.1 - 2.2 7.7 5.3 1.8 8.0 0.1 3.0 3 0 0 3 3 3 0 Herpesvirus ICP4-like protein N-terminal region FGGY_C PF02782.11 EDO15042.1 - 4.1e-46 157.1 0.0 6e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EDO15042.1 - 1.6e-26 93.1 0.2 1.5e-25 89.9 0.2 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 EDO15042.1 - 0.0037 16.6 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 Hexokinase UPF0075 PF03702.9 EDO15042.1 - 0.015 14.2 0.0 0.053 12.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0075) BcrAD_BadFG PF01869.15 EDO15042.1 - 0.13 11.5 1.5 0.36 10.0 0.6 2.1 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Rax2 PF12768.2 EDO15043.1 - 2.7e-75 253.2 10.4 2.7e-75 253.2 7.2 4.7 5 1 1 6 6 6 1 Cortical protein marker for cell polarity Kelch_6 PF13964.1 EDO15043.1 - 0.028 14.6 7.0 0.17 12.1 0.1 4.1 4 0 0 4 4 4 0 Kelch motif TRAPPC-Trs85 PF12739.2 EDO15044.1 - 1.9e-101 339.7 3.2 2.6e-101 339.2 2.2 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit COPIIcoated_ERV PF07970.7 EDO15046.1 - 1.6e-75 253.5 0.8 2.3e-75 253.0 0.5 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EDO15046.1 - 1.2e-28 98.9 0.3 2.5e-28 97.8 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CDC24 PF06395.6 EDO15047.1 - 3.9e-36 122.9 0.8 1.1e-35 121.5 0.6 1.9 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 EDO15047.1 - 2.2e-34 118.9 5.9 2.2e-34 118.9 4.1 2.3 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.1 EDO15047.1 - 7.3e-22 77.7 2.4 7.3e-22 77.7 1.7 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain PB1 PF00564.19 EDO15047.1 - 1e-05 25.0 1.4 3.7e-05 23.3 0.3 2.4 3 0 0 3 3 3 1 PB1 domain PH PF00169.24 EDO15047.1 - 0.01 16.0 4.4 0.015 15.4 1.2 2.6 2 0 0 2 2 2 0 PH domain Cupin_8 PF13621.1 EDO15049.1 - 7.5e-51 173.0 0.0 1.1e-49 169.1 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EDO15049.1 - 0.0075 16.5 0.0 0.036 14.3 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EDO15049.1 - 0.026 13.7 0.0 0.36 10.0 0.0 2.4 2 0 0 2 2 2 0 Cupin superfamily protein Cyclin_N PF00134.18 EDO15050.1 - 7.4e-25 86.9 1.0 2e-24 85.5 0.7 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2291 PF10054.4 EDO15050.1 - 0.036 13.3 1.3 0.063 12.5 0.9 1.3 1 0 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) AA_permease PF00324.16 EDO15052.1 - 1.6e-133 445.5 41.2 1.9e-133 445.2 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO15052.1 - 2.3e-24 85.7 45.9 2.8e-24 85.4 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease DUF485 PF04341.7 EDO15052.1 - 2.8 7.7 0.0 2.8 7.7 0.0 3.5 2 1 1 3 3 3 0 Protein of unknown function, DUF485 PK PF00224.16 EDO15053.1 - 1.7e-159 530.0 0.0 2.2e-159 529.7 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EDO15053.1 - 5.4e-32 109.8 0.2 1.5e-31 108.3 0.0 1.8 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EDO15053.1 - 1.2e-05 24.3 0.3 3.3e-05 22.8 0.1 1.7 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EDO15053.1 - 0.029 13.2 0.0 0.49 9.2 0.0 2.3 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain IMS PF00817.15 EDO15054.1 - 1.4e-24 86.6 0.0 3.4e-24 85.3 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EDO15054.1 - 3e-12 46.5 0.0 6.9e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 EDO15054.1 - 6.8e-12 45.3 1.2 2.6e-11 43.5 0.1 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EDO15054.1 - 2.1e-05 24.2 0.0 7.7e-05 22.4 0.0 2.1 1 0 0 1 1 1 1 twin BRCT domain DUF4414 PF14377.1 EDO15054.1 - 0.019 14.8 0.5 0.06 13.2 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 EDO15054.1 - 0.021 14.8 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 IMS family HHH motif HLH PF00010.21 EDO15055.1 - 1.6e-22 78.9 0.2 4.5e-22 77.5 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zf-CCHC PF00098.18 EDO15056.1 - 0.00054 19.7 15.7 0.0029 17.4 3.6 5.7 6 0 0 6 6 6 3 Zinc knuckle zf-CCHC_2 PF13696.1 EDO15056.1 - 0.033 13.6 1.0 0.033 13.6 0.7 4.8 3 2 1 4 4 4 0 Zinc knuckle Mfp-3 PF04202.8 EDO15056.1 - 0.74 10.0 8.6 2.4 8.3 6.0 2.0 1 0 0 1 1 1 0 Foot protein 3 zf-CCHC_4 PF14392.1 EDO15056.1 - 5.5 6.7 39.2 0.53 9.9 0.5 5.4 4 1 1 5 5 5 0 Zinc knuckle tRNA-synt_2b PF00587.20 EDO15057.1 - 4.6e-46 156.5 1.0 7.9e-46 155.7 0.7 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO15057.1 - 2.6e-20 72.1 0.4 5.6e-20 71.0 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EDO15057.1 - 2.6e-14 52.7 0.0 5.4e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 EDO15057.1 - 1.4e-12 47.3 0.0 2.7e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Coatomer_E PF04733.9 EDO15058.1 - 8.7e-07 28.4 10.1 2.1e-05 23.8 7.0 2.4 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EDO15058.1 - 5.7e-05 23.3 1.9 0.23 11.8 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO15058.1 - 0.0023 17.7 0.1 7.1 6.8 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO15058.1 - 0.0096 16.5 0.2 4.7 8.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO15058.1 - 0.025 14.7 3.6 2 8.6 0.2 3.4 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EDO15058.1 - 0.065 13.9 0.1 4.7 8.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EDO15058.1 - 0.08 13.4 0.0 10 6.8 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO15058.1 - 0.1 12.2 0.8 40 4.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDO15058.1 - 0.21 11.8 1.5 1.2 9.5 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Phage_connect_1 PF05135.8 EDO15058.1 - 1.2 9.3 4.7 3.4 7.8 1.2 3.2 2 1 1 3 3 3 0 Phage gp6-like head-tail connector protein GET2 PF08690.5 EDO15059.1 - 5.8e-109 364.0 3.1 6.5e-109 363.8 2.2 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 2-Hacid_dh_C PF02826.14 EDO15060.1 - 1.8e-50 170.5 0.0 3.4e-50 169.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDO15060.1 - 4.3e-37 126.5 0.0 5.6e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDO15060.1 - 2.9e-05 23.9 0.3 0.0001 22.2 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EDO15060.1 - 0.0024 17.7 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.20 EDO15060.1 - 0.0029 17.0 0.1 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 ACT domain SPO22 PF08631.5 EDO15061.1 - 6.9e-86 287.7 7.8 6.9e-86 287.7 5.4 4.2 3 2 1 4 4 4 3 Meiosis protein SPO22/ZIP4 like DUF3781 PF12636.2 EDO15062.1 - 0.11 12.5 0.1 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) HORMA PF02301.13 EDO15063.1 - 6.4e-49 166.2 0.5 6.4e-49 166.2 0.4 2.6 2 1 1 3 3 3 1 HORMA domain C1_1 PF00130.17 EDO15063.1 - 0.04 13.6 2.8 0.097 12.4 1.9 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 EDO15063.1 - 0.075 12.3 8.6 0.02 14.2 2.7 2.5 3 0 0 3 3 3 0 PHD-finger Peptidase_M24 PF00557.19 EDO15064.1 - 4.6e-53 179.8 0.0 6.9e-53 179.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EDO15064.1 - 9.3e-32 109.2 0.0 3.3e-31 107.4 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Yos1 PF08571.5 EDO15065.1 - 1.1e-31 108.7 2.4 1.2e-31 108.6 1.7 1.0 1 0 0 1 1 1 1 Yos1-like Ribosomal_S24e PF01282.14 EDO15066.1 - 7.6e-35 118.5 0.1 1.1e-34 118.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e LCCL PF03815.14 EDO15067.1 - 1.6e-09 37.6 0.2 2.9e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 LCCL domain OppC_N PF12911.2 EDO15067.1 - 1.3 8.4 4.4 15 5.0 1.0 3.1 2 1 1 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Ribonuc_red_lgC PF02867.10 EDO15068.1 - 2.4e-214 712.9 0.0 3.2e-214 712.4 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EDO15068.1 - 1.6e-24 85.4 0.1 4.2e-24 84.1 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EDO15068.1 - 2.9e-17 62.8 0.0 1.3e-16 60.8 0.0 2.2 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 EDO15068.1 - 1.4e-05 23.3 0.0 2.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase Methyltransf_31 PF13847.1 EDO15069.1 - 3.9e-26 91.4 0.3 5.5e-26 90.9 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO15069.1 - 9.7e-20 71.2 0.0 1.5e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO15069.1 - 2.2e-08 34.4 0.1 5.1e-08 33.3 0.1 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO15069.1 - 5.4e-08 32.8 0.0 1.1e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EDO15069.1 - 2.8e-07 30.3 0.0 3.5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO15069.1 - 3.4e-07 30.6 0.0 5.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO15069.1 - 5.6e-07 29.8 0.0 9.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO15069.1 - 3.1e-06 26.4 0.1 4e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EDO15069.1 - 5.5e-06 25.8 0.0 9.4e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EDO15069.1 - 0.00024 20.8 0.0 0.00048 19.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.3 EDO15069.1 - 0.0004 19.3 0.1 0.0013 17.6 0.0 1.7 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_4 PF02390.12 EDO15069.1 - 0.00079 18.5 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 EDO15069.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.13 EDO15069.1 - 0.0035 16.4 0.1 0.0053 15.8 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EDO15069.1 - 0.033 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EDO15069.1 - 0.05 13.1 0.0 0.098 12.2 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 DOT1 PF08123.8 EDO15069.1 - 0.086 12.1 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 P16-Arc PF04699.9 EDO15070.1 - 1.5e-54 184.1 0.0 1.7e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Sigma70_r4_2 PF08281.7 EDO15070.1 - 0.032 13.7 0.0 0.072 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 DUF619 PF04768.8 EDO15071.1 - 1.6e-54 183.9 1.0 2.6e-54 183.1 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 EDO15071.1 - 3.8e-18 65.9 0.0 7.1e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 Amino acid kinase family zf-RING_4 PF14570.1 EDO15072.1 - 2.5e-19 68.6 13.1 4.6e-19 67.7 9.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 EDO15072.1 - 1.2e-06 28.2 1.6 5.4e-06 26.1 1.1 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO15072.1 - 5.8e-06 25.8 0.2 0.00015 21.3 0.1 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 EDO15072.1 - 1.1e-05 24.7 25.8 0.00013 21.3 1.3 2.5 2 0 0 2 2 2 2 Rtf2 RING-finger zf-C3HC4_3 PF13920.1 EDO15072.1 - 1.9e-05 24.2 6.6 3.9e-05 23.2 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 EDO15072.1 - 3.1e-05 23.7 3.8 3.1e-05 23.7 2.6 3.0 3 1 1 4 4 3 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.1 EDO15072.1 - 0.0003 20.5 8.4 0.00058 19.6 5.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDO15072.1 - 0.0019 17.7 10.6 0.0043 16.6 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 EDO15072.1 - 0.0071 16.2 0.1 0.029 14.3 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 EDO15072.1 - 0.012 14.8 0.0 0.03 13.6 0.0 1.6 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-C3HC4_2 PF13923.1 EDO15072.1 - 0.03 14.3 10.6 0.062 13.3 7.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO15072.1 - 0.05 13.3 9.6 0.11 12.2 6.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain AAA_23 PF13476.1 EDO15072.1 - 0.13 12.5 31.2 0.023 15.0 16.8 2.5 2 0 0 2 2 2 0 AAA domain Peptidase_S49_N PF08496.5 EDO15072.1 - 0.51 10.1 27.7 0.12 12.1 0.3 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Cellulose_synt PF03552.9 EDO15072.1 - 0.61 8.3 6.2 1.2 7.3 4.3 1.4 1 0 0 1 1 1 0 Cellulose synthase Spore_coat_CotO PF14153.1 EDO15072.1 - 0.72 9.2 41.3 14 5.0 0.1 3.5 3 0 0 3 3 3 0 Spore coat protein CotO Zip PF02535.17 EDO15072.1 - 1.1 8.2 12.8 0.35 9.8 5.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter RR_TM4-6 PF06459.7 EDO15072.1 - 2 8.2 22.8 0.56 10.0 11.0 2.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 zf-C3HC4_4 PF15227.1 EDO15072.1 - 3.5 7.5 11.2 20 5.1 7.8 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FYDLN_acid PF09538.5 EDO15072.1 - 3.9 8.0 15.1 13 6.4 5.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2578 PF10843.3 EDO15073.1 - 2.6e-66 223.0 14.6 3e-66 222.8 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) Rrn6 PF10214.4 EDO15073.1 - 0.0065 14.6 0.6 0.008 14.3 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DIX PF00778.12 EDO15073.1 - 0.021 14.5 0.5 0.021 14.5 0.3 2.2 2 0 0 2 2 2 0 DIX domain Med11 PF10280.4 EDO15073.1 - 0.057 13.4 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex protein DUF4314 PF14192.1 EDO15073.1 - 0.27 11.5 1.5 4 7.7 0.2 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4314) Bac_rhodopsin PF01036.13 EDO15075.1 - 1.2e-45 155.5 16.4 1.6e-45 155.1 11.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2838 PF10998.3 EDO15075.1 - 1 9.2 13.0 0.72 9.7 1.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2838) DUF1772 PF08592.6 EDO15075.1 - 1.1 8.9 7.8 0.4 10.4 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) TSGP1 PF07771.6 EDO15075.1 - 1.9 8.3 4.5 3.1 7.7 3.1 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 Snf7 PF03357.16 EDO15076.1 - 7.5e-35 119.8 9.8 9.9e-35 119.4 6.8 1.1 1 0 0 1 1 1 1 Snf7 MAD PF05557.8 EDO15076.1 - 0.0051 14.9 9.1 0.0066 14.6 6.3 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF3573 PF12097.3 EDO15076.1 - 0.67 8.5 4.3 0.86 8.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF948 PF06103.6 EDO15076.1 - 0.85 9.5 3.8 0.82 9.5 0.6 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) DASH_Duo1 PF08651.5 EDO15076.1 - 0.96 9.0 5.4 0.82 9.2 0.1 3.0 2 1 1 3 3 3 0 DASH complex subunit Duo1 NPV_P10 PF05531.7 EDO15076.1 - 1.9 8.7 8.0 9.3 6.5 0.2 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein CLTH PF10607.4 EDO15076.1 - 2.6 7.7 7.7 6.4 6.4 5.4 1.7 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain SlyX PF04102.7 EDO15076.1 - 5.3 7.5 12.0 2.5 8.5 0.8 3.3 2 1 2 4 4 4 0 SlyX AAA PF00004.24 EDO15077.1 - 7.7e-11 42.3 0.1 6.3e-10 39.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EDO15077.1 - 3.7e-05 23.6 0.5 3.7e-05 23.6 0.3 3.4 4 1 0 4 4 4 1 AAA domain RuvB_N PF05496.7 EDO15077.1 - 0.00017 20.7 0.0 0.00032 19.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EDO15077.1 - 0.00028 21.7 3.8 0.0011 19.8 0.0 3.7 3 2 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EDO15077.1 - 0.00086 19.4 0.0 0.004 17.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDO15077.1 - 0.0052 16.5 0.0 0.064 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDO15077.1 - 0.006 16.4 0.0 0.018 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO15077.1 - 0.014 15.3 0.0 0.037 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EDO15077.1 - 0.019 15.2 0.1 0.019 15.2 0.1 6.1 4 4 1 5 5 5 0 AAA domain DUF258 PF03193.11 EDO15077.1 - 0.026 13.7 0.0 0.068 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EDO15077.1 - 0.047 13.4 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EDO15077.1 - 0.051 13.7 5.2 0.39 10.8 0.1 4.1 3 2 0 3 3 3 0 RNA helicase IstB_IS21 PF01695.12 EDO15077.1 - 0.083 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein IPT PF01745.11 EDO15077.1 - 0.091 11.9 0.1 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase AAA_11 PF13086.1 EDO15077.1 - 3.4 7.1 12.7 0.23 10.9 2.3 2.6 2 1 0 2 2 2 0 AAA domain PIR PF00399.14 EDO15079.1 - 1.5e-15 55.8 26.7 1.9e-08 33.3 6.7 2.5 2 0 0 2 2 2 2 Yeast PIR protein repeat Synuclein PF01387.12 EDO15079.1 - 0.36 10.7 4.4 0.45 10.4 3.1 1.1 1 0 0 1 1 1 0 Synuclein Mucin PF01456.12 EDO15079.1 - 1.2 8.9 10.4 1.4 8.6 7.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Utp11 PF03998.8 EDO15080.1 - 4.9e-71 239.3 39.8 5.5e-71 239.2 27.6 1.0 1 0 0 1 1 1 1 Utp11 protein DUF267 PF03268.9 EDO15080.1 - 6.5 5.4 6.4 3.6 6.3 1.4 2.1 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 ADH_zinc_N PF00107.21 EDO15081.1 - 1.2e-29 102.4 0.4 1.8e-29 101.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO15081.1 - 1.3e-29 102.1 0.9 2.8e-29 101.0 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EDO15081.1 - 3.6e-05 24.6 0.1 0.00011 23.0 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Pkinase PF00069.20 EDO15082.1 - 5.8e-72 241.9 0.1 2.2e-71 240.0 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15082.1 - 4.2e-36 124.3 0.0 2.9e-34 118.3 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EDO15082.1 - 0.0044 16.7 0.0 0.014 15.1 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDO15082.1 - 0.038 13.0 0.0 0.078 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M18 PF02127.10 EDO15083.1 - 2.4e-130 434.9 0.0 3.4e-130 434.4 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) SIS PF01380.17 EDO15084.1 - 7.9e-62 206.6 0.0 2.8e-32 111.0 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EDO15084.1 - 3.3e-30 105.0 0.0 9.8e-22 77.1 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EDO15084.1 - 1.3e-18 67.2 0.0 2.6e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EDO15084.1 - 6.7e-12 45.2 0.0 1.4e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EDO15084.1 - 7.1e-09 34.7 0.1 1.3e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II COMPASS-Shg1 PF05205.7 EDO15084.1 - 0.062 13.6 0.1 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 SIS_2 PF13580.1 EDO15084.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 SIS domain DUF4350 PF14258.1 EDO15084.1 - 0.16 12.2 0.0 2.7 8.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) Flocculin PF00624.13 EDO15086.1 - 9.2e-153 495.9 466.4 1.5e-15 56.7 18.0 24.0 15 1 4 19 19 19 14 Flocculin repeat Flocculin PF00624.13 EDO15087.1 - 4e-25 87.3 77.9 2.5e-12 46.4 22.3 4.6 5 0 0 5 5 5 3 Flocculin repeat Pyridox_oxidase PF01243.15 EDO15087.1 - 0.008 16.1 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase VCX_VCY PF15231.1 EDO15088.1 - 1.3 9.3 22.3 15 5.9 5.9 2.8 1 1 1 2 2 2 0 Variable charge X/Y family Flocculin PF00624.13 EDO15089.1 - 1.5e-75 248.7 304.6 3.1e-12 46.1 13.8 36.1 34 2 1 36 36 36 16 Flocculin repeat MFS_1 PF07690.11 EDO15090.1 - 1.1e-07 30.9 45.1 7.6e-06 24.8 11.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO15090.1 - 1.2e-06 27.3 26.6 4.1e-06 25.6 4.7 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDO15091.1 - 2.6e-09 36.2 38.4 6.7e-07 28.3 26.6 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Vg_Tdu PF07545.9 EDO15091.1 - 0.023 14.1 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 Vestigial/Tondu family Epimerase PF01370.16 EDO15092.1 - 3.2e-18 66.0 0.0 3.9e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDO15092.1 - 8.8e-13 47.5 0.1 1.3e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EDO15092.1 - 3.5e-08 33.6 0.3 1.7e-07 31.4 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EDO15092.1 - 2.1e-07 30.1 0.1 7e-07 28.4 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EDO15092.1 - 2.9e-06 26.4 0.1 6.9e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EDO15092.1 - 1.1e-05 25.4 0.0 2.2e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EDO15092.1 - 4.3e-05 22.8 0.6 0.034 13.4 0.0 2.3 2 1 0 2 2 2 2 NmrA-like family KR PF08659.5 EDO15092.1 - 0.0049 16.5 0.0 0.0089 15.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Thiolase_N PF00108.18 EDO15094.1 - 1.4e-85 286.4 0.0 1.9e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EDO15094.1 - 5.8e-48 161.3 0.6 1.2e-47 160.4 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EDO15094.1 - 0.0015 18.0 0.2 0.0047 16.4 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Trigger_C PF05698.9 EDO15094.1 - 0.032 14.0 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus ACP_syn_III PF08545.5 EDO15094.1 - 0.35 10.5 2.4 0.77 9.4 0.0 2.5 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF2040 PF09745.4 EDO15096.1 - 4.2e-08 33.0 14.0 1.1e-07 31.7 9.6 1.8 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) Inos-1-P_synth PF01658.12 EDO15096.1 - 0.0092 15.8 4.2 0.0092 15.8 2.9 2.6 1 1 1 2 2 2 1 Myo-inositol-1-phosphate synthase vATP-synt_E PF01991.13 EDO15097.1 - 8e-51 172.1 22.5 9.3e-51 171.9 15.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phlebovirus_NSM PF07246.6 EDO15097.1 - 0.004 16.3 13.1 0.0065 15.6 9.1 1.3 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M CorA PF01544.13 EDO15098.1 - 2.4e-07 30.1 4.7 3.8e-07 29.4 3.3 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein AAA_27 PF13514.1 EDO15099.1 - 0.011 13.4 0.2 0.017 12.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain SKIP_SNW PF02731.10 EDO15100.1 - 1.4e-49 167.5 10.9 1.4e-49 167.5 7.5 2.4 3 0 0 3 3 3 1 SKIP/SNW domain RNase_P_Rpp14 PF01900.14 EDO15101.1 - 7.7e-34 115.8 0.1 9.4e-34 115.5 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family Peptidase_M85 PF13678.1 EDO15101.1 - 0.091 12.1 0.0 3.8 6.8 0.0 2.0 1 1 1 2 2 2 0 NFkB-p65-degrading zinc protease tRNA-synt_2c PF01411.14 EDO15102.1 - 1.4e-214 713.5 0.3 1.4e-214 713.5 0.2 1.9 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EDO15102.1 - 9.5e-17 60.6 0.2 2.9e-16 59.0 0.1 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EDO15102.1 - 0.00033 20.2 0.1 0.00088 18.9 0.1 1.8 1 0 0 1 1 1 1 DHHA1 domain Fungal_trans PF04082.13 EDO15103.1 - 1.4e-36 125.7 3.9 3.5e-36 124.4 2.7 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO15103.1 - 6.1e-07 29.2 9.3 1.1e-06 28.3 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Vps16_C PF04840.7 EDO15103.1 - 0.0043 16.0 0.1 0.042 12.8 0.1 2.1 2 0 0 2 2 2 1 Vps16, C-terminal region SWIRM PF04433.12 EDO15104.1 - 4.7e-14 52.2 0.0 8.4e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain TIM PF00121.13 EDO15105.1 - 3.7e-88 294.7 0.3 4.2e-88 294.5 0.2 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase SNF2_N PF00176.18 EDO15107.1 - 1.6e-41 142.0 0.0 2.1e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EDO15107.1 - 4.3e-10 39.7 0.6 9.1e-10 38.6 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDO15107.1 - 8.8e-09 35.0 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2439 PF10382.4 EDO15107.1 - 9.3e-05 22.5 1.3 0.00022 21.3 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) HDA2-3 PF11496.3 EDO15108.1 - 3.6e-12 45.7 2.0 3e-08 32.8 0.3 2.2 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 EDO15108.1 - 2.1e-11 43.5 0.0 6.3e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_12 PF13087.1 EDO15108.1 - 0.019 14.3 1.0 0.031 13.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain Vps51 PF08700.6 EDO15108.1 - 1.4 8.8 5.3 0.29 11.0 0.2 2.3 3 0 0 3 3 3 0 Vps51/Vps67 URO-D PF01208.12 EDO15109.1 - 4.2e-123 410.6 0.0 4.8e-123 410.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF4451 PF14616.1 EDO15110.1 - 3.4e-06 26.8 2.4 3.4e-06 26.8 1.6 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4451) Sugar_tr PF00083.19 EDO15111.1 - 6e-60 203.0 7.3 7.6e-60 202.7 5.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO15111.1 - 2.2e-07 29.9 12.0 3.4e-06 26.0 4.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Frag1 PF10277.4 EDO15113.1 - 5.8e-33 114.1 13.8 5.8e-33 114.1 9.6 3.2 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family COX6B PF02297.12 EDO15114.1 - 3.3e-21 75.0 4.7 3.9e-21 74.8 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Somatostatin PF03002.10 EDO15114.1 - 0.0049 16.4 0.4 0.012 15.2 0.3 1.7 1 0 0 1 1 1 1 Somatostatin/Cortistatin family APOBEC_C PF05240.9 EDO15114.1 - 0.045 13.1 0.6 0.061 12.7 0.4 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UPF0203 PF05254.7 EDO15114.1 - 0.34 10.7 5.4 2.1 8.2 1.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) RIC1 PF07064.8 EDO15115.1 - 5.2e-18 65.4 1.6 1e-17 64.4 1.1 1.4 1 0 0 1 1 1 1 RIC1 GATA PF00320.22 EDO15116.1 - 5.5e-15 54.4 4.4 1e-14 53.5 3.1 1.5 1 0 0 1 1 1 1 GATA zinc finger TPP_enzyme_N PF02776.13 EDO15117.1 - 6.7e-25 87.5 0.0 8e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Ribosomal_60s PF00428.14 EDO15118.1 - 3.4e-21 75.4 6.5 4.1e-21 75.1 4.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S9 PF00380.14 EDO15119.1 - 1.5e-38 131.7 0.2 1.6e-38 131.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Rad17 PF03215.10 EDO15120.1 - 4.9e-87 292.7 6.6 2.1e-62 211.4 0.7 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA PF00004.24 EDO15120.1 - 0.0008 19.6 0.0 0.0023 18.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO15120.1 - 0.002 18.1 0.2 0.0063 16.5 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EDO15120.1 - 0.007 15.3 0.0 0.017 14.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EDO15120.1 - 0.011 15.9 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDO15120.1 - 0.025 14.3 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EDO15120.1 - 0.063 13.5 0.2 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 EDO15120.1 - 0.078 13.7 3.1 1.1 10.1 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EDO15120.1 - 0.12 11.9 0.2 0.28 10.7 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glutaredoxin PF00462.19 EDO15121.1 - 2.1e-20 72.4 0.6 7.3e-18 64.3 0.0 2.8 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.15 EDO15121.1 - 1e-16 60.5 0.1 1.8e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EDO15121.1 - 1.4e-08 34.7 0.2 2.7e-06 27.4 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 EDO15121.1 - 1.4e-07 31.2 0.1 2.1e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 EDO15121.1 - 9.2e-05 22.6 0.0 0.00094 19.3 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.5 EDO15121.1 - 0.0002 20.9 0.1 0.00053 19.5 0.1 1.7 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 EDO15121.1 - 0.00022 21.1 0.1 0.00098 19.1 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Spt5_N PF11942.3 EDO15121.1 - 0.013 16.1 4.6 0.024 15.2 3.2 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Ribosomal_60s PF00428.14 EDO15121.1 - 0.048 14.0 3.7 0.11 12.9 2.6 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Olfactory_mark PF06554.7 EDO15121.1 - 0.068 12.7 0.2 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Olfactory marker protein ArsC PF03960.10 EDO15121.1 - 0.099 12.7 0.0 0.71 9.9 0.0 2.2 2 1 1 3 3 3 0 ArsC family AAA_12 PF13087.1 EDO15122.1 - 1.7e-62 210.3 3.3 5.5e-62 208.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EDO15122.1 - 5.3e-44 150.5 0.7 5.3e-44 150.5 0.5 3.9 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.1 EDO15122.1 - 7.5e-10 38.7 0.0 9.3e-09 35.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO15122.1 - 2.3e-09 36.8 0.0 5.9e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EDO15122.1 - 1.1e-06 28.4 3.0 0.079 12.4 0.0 4.1 5 0 0 5 5 5 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EDO15122.1 - 0.00049 19.6 0.5 0.0018 17.7 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA PF00004.24 EDO15122.1 - 0.0013 18.9 0.0 0.022 14.9 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EDO15122.1 - 0.0037 16.5 0.1 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein UvrD_C_2 PF13538.1 EDO15122.1 - 0.0053 16.8 0.0 0.02 15.0 0.0 2.1 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.12 EDO15122.1 - 0.032 13.6 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_25 PF13481.1 EDO15122.1 - 0.082 12.2 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EDO15122.1 - 0.17 11.8 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain zf-C2H2_2 PF12756.2 EDO15122.1 - 2.9 8.0 12.7 0.11 12.5 3.8 2.6 2 0 0 2 2 1 0 C2H2 type zinc-finger (2 copies) RVT_2 PF07727.9 EDO15123.1 - 1.7e-39 135.2 0.8 1.7e-39 135.2 0.6 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Enkurin PF13864.1 EDO15123.1 - 0.025 14.7 0.6 0.025 14.7 0.4 3.8 4 0 0 4 4 4 0 Calmodulin-binding N2227 PF07942.7 EDO15126.1 - 3.8e-60 203.1 0.1 6.8e-60 202.3 0.1 1.4 1 0 0 1 1 1 1 N2227-like protein MFS_1 PF07690.11 EDO15127.1 - 4.7e-23 81.4 38.5 4.7e-23 81.4 26.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily BRO1 PF03097.13 EDO15128.1 - 5.5e-92 308.4 5.5 5.5e-92 308.4 3.8 2.1 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EDO15128.1 - 1.1e-26 93.5 10.5 1.1e-26 93.5 7.3 2.3 2 2 0 2 2 2 1 ALIX V-shaped domain binding to HIV GerA PF03323.8 EDO15128.1 - 0.16 10.0 1.1 0.25 9.4 0.8 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Fib_alpha PF08702.5 EDO15128.1 - 2.5 8.2 9.8 2.6 8.1 1.3 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family KMP11 PF03037.11 EDO15128.1 - 9.5 6.8 12.0 1.4 9.5 0.7 3.6 4 0 0 4 4 4 0 Kinetoplastid membrane protein 11 Myb_DNA-binding PF00249.26 EDO15130.1 - 3.6e-20 71.7 0.9 1.1e-09 38.2 0.1 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO15130.1 - 2.2e-15 56.4 1.0 2.9e-09 36.8 0.3 3.3 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EDO15130.1 - 0.053 13.4 1.1 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain YHYH PF14240.1 EDO15131.1 - 0.11 12.1 1.3 0.14 11.7 0.9 1.3 1 1 0 1 1 1 0 YHYH protein RNA_pol_Rpb2_5 PF04567.12 EDO15131.1 - 0.51 10.3 0.0 0.51 10.3 0.0 2.2 3 1 0 3 3 3 0 RNA polymerase Rpb2, domain 5 Pkinase PF00069.20 EDO15132.1 - 4.3e-41 140.7 2.0 1.8e-20 73.2 0.5 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15132.1 - 6.3e-10 38.5 3.1 0.0082 15.2 0.3 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EDO15132.1 - 0.024 13.4 0.4 0.14 10.9 0.3 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase GMP_synt_C PF00958.17 EDO15133.1 - 1.6e-40 136.7 0.0 3.3e-40 135.7 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EDO15133.1 - 1.1e-39 135.9 0.0 1.8e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EDO15133.1 - 3.7e-08 32.5 0.0 7.2e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EDO15133.1 - 7.7e-08 32.0 0.1 4.6e-07 29.4 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.8 EDO15133.1 - 0.013 14.7 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 EDO15133.1 - 0.023 13.7 0.1 0.036 13.1 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.9 EDO15133.1 - 0.027 13.9 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 EDO15133.1 - 0.033 14.0 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family tRNA_Me_trans PF03054.11 EDO15133.1 - 0.043 12.3 0.0 0.086 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase MFS_1 PF07690.11 EDO15136.1 - 1.7e-10 40.1 18.1 2e-10 39.9 11.5 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily FSH1 PF03959.8 EDO15137.1 - 9.1e-66 221.3 0.0 1.1e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EDO15137.1 - 1.7e-09 37.5 0.0 2.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDO15137.1 - 3.8e-05 23.2 0.0 8.5e-05 22.0 0.0 1.8 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EDO15137.1 - 0.00044 20.1 0.0 0.15 11.9 0.0 2.2 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO15137.1 - 0.093 12.2 0.0 0.98 8.9 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 EDO15137.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Phosducin PF02114.11 EDO15138.1 - 1.1e-06 27.5 5.8 0.007 15.1 1.4 2.3 1 1 0 2 2 2 2 Phosducin DUF2027 PF09640.5 EDO15138.1 - 0.037 13.3 0.1 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2027) Orthopox_F7 PF05813.7 EDO15138.1 - 0.07 13.0 1.6 1.1 9.2 0.2 2.6 1 1 1 2 2 2 0 Orthopoxvirus F7 protein Mre11_DNA_bind PF04152.9 EDO15139.1 - 2e-53 180.8 1.1 2e-53 180.8 0.8 2.4 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EDO15139.1 - 2.9e-29 101.8 0.9 2.9e-29 101.8 0.6 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDO15139.1 - 3.9e-05 23.5 0.0 0.0001 22.1 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain His_Phos_1 PF00300.17 EDO15140.1 - 1.1e-31 110.0 0.1 1.4e-31 109.7 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3530 PF12048.3 EDO15140.1 - 0.11 11.4 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DUF4062 PF13271.1 EDO15140.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) Rhodanese PF00581.15 EDO15141.1 - 1.5e-17 64.0 0.0 1.8e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain NOGCT PF08155.6 EDO15142.1 - 1.3e-27 95.2 1.3 3.7e-27 93.7 0.9 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EDO15142.1 - 1.5e-27 95.2 0.4 3.8e-27 93.9 0.3 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EDO15142.1 - 6.9e-16 58.2 0.0 1.7e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO15142.1 - 1e-07 31.3 0.0 2.3e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EDO15142.1 - 0.0012 18.0 0.1 0.0023 17.0 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDO15142.1 - 0.0024 18.3 0.1 0.0096 16.4 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EDO15142.1 - 0.026 14.3 0.0 10 5.9 0.0 2.8 1 1 1 2 2 2 0 Dynamin family AAA_23 PF13476.1 EDO15142.1 - 3.5 7.9 8.3 12 6.1 0.0 2.9 2 2 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.9 EDO15143.1 - 2e-37 129.0 1.3 3e-37 128.4 0.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EDO15143.1 - 3.2e-32 110.8 0.1 1.3e-30 105.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EDO15143.1 - 1.1e-22 80.1 7.0 1.1e-20 73.7 0.5 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDO15143.1 - 1.5e-10 40.7 0.2 4.6e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDO15143.1 - 7e-08 32.7 0.4 2.9e-06 27.5 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EDO15143.1 - 7.2e-07 28.9 0.5 0.00071 19.1 0.1 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EDO15143.1 - 2.6e-06 26.5 3.0 7.8e-05 21.6 0.5 2.5 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EDO15143.1 - 4.4e-06 25.4 8.8 0.0022 16.5 0.5 3.9 3 1 1 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 EDO15143.1 - 2.4e-05 23.4 0.0 4.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EDO15143.1 - 2.6e-05 23.3 0.1 2.6e-05 23.3 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO15143.1 - 0.00012 22.0 1.2 0.00012 22.0 0.8 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDO15143.1 - 0.00037 19.6 2.6 0.00048 19.3 0.4 2.2 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 EDO15143.1 - 0.001 18.7 3.1 0.026 14.2 0.1 2.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EDO15143.1 - 0.0011 18.1 0.5 0.59 9.2 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EDO15143.1 - 0.0022 16.9 5.7 0.0074 15.1 2.6 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 EDO15143.1 - 0.0092 16.2 0.2 0.72 10.1 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EDO15143.1 - 0.023 14.4 3.1 2.1 8.0 0.1 2.6 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EDO15143.1 - 0.04 13.2 0.4 0.1 11.9 0.3 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 EDO15143.1 - 1.3 8.0 4.8 5.1 6.0 0.7 2.2 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.11 EDO15143.1 - 9.4 5.6 7.3 0.51 9.7 0.1 2.5 3 1 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Ribosomal_S6e PF01092.14 EDO15144.1 - 2.1e-61 205.2 0.6 3.7e-61 204.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e SRF-TF PF00319.13 EDO15145.1 - 1.4e-22 78.6 0.2 3.2e-22 77.5 0.1 1.7 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) AMP-binding PF00501.23 EDO15146.1 - 3.9e-87 292.3 0.1 5e-87 291.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO15146.1 - 1.6e-17 64.2 1.2 3.5e-17 63.1 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Mem_trans PF03547.13 EDO15147.1 - 7.5e-57 192.3 6.5 1.1e-56 191.7 4.5 1.2 1 0 0 1 1 1 1 Membrane transport protein Reticulon PF02453.12 EDO15147.1 - 0.61 9.6 10.5 1.8 8.1 2.0 2.8 3 0 0 3 3 3 0 Reticulon Stm1_N PF09598.5 EDO15148.1 - 9.6e-18 64.6 5.1 9.6e-18 64.6 3.5 3.9 4 1 0 4 4 4 2 Stm1 Stb3 PF10330.4 EDO15149.1 - 8.4e-34 115.1 0.1 2.1e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 Putative Sin3 binding protein TFIID_30kDa PF03540.8 EDO15150.1 - 2.3e-27 94.5 0.1 4e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Band_3_cyto PF07565.8 EDO15150.1 - 0.0039 16.7 3.7 0.0039 16.7 2.6 1.9 1 1 1 2 2 2 1 Band 3 cytoplasmic domain PXA PF02194.10 EDO15150.1 - 0.81 9.2 5.6 0.23 10.9 1.6 1.7 2 0 0 2 2 2 0 PXA domain Pex14_N PF04695.8 EDO15150.1 - 1.4 8.9 12.8 0.68 9.9 3.8 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec5 PF15469.1 EDO15151.1 - 1.8e-42 145.1 15.8 1.8e-42 145.1 11.0 3.0 3 0 0 3 3 3 1 Exocyst complex component Sec5 Spermine_synth PF01564.12 EDO15152.1 - 1.1e-91 306.2 0.4 1.4e-91 305.8 0.3 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EDO15152.1 - 0.001 19.6 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO15152.1 - 0.0037 16.9 0.0 0.012 15.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO15152.1 - 0.026 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EDO15152.1 - 0.049 14.1 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EDO15152.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Post_transc_reg PF13797.1 EDO15153.1 - 1.1 8.9 7.0 10 5.8 0.0 3.4 3 2 0 3 3 3 0 Post-transcriptional regulator Gag_p17 PF00540.13 EDO15153.1 - 2.8 7.7 5.2 0.55 9.9 0.2 2.2 3 0 0 3 3 3 0 gag gene protein p17 (matrix protein) Glyco_hydro_81 PF03639.8 EDO15154.1 - 1.3e-227 757.2 10.3 1.6e-227 756.9 7.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 F1F0-ATPsyn_F PF10791.4 EDO15155.1 - 1.3e-43 147.1 0.1 1.4e-43 146.9 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EDO15155.1 - 0.0051 16.8 0.0 0.0074 16.3 0.0 1.3 1 1 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ABC_sub_bind PF04392.7 EDO15155.1 - 0.092 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter substrate binding protein AIRC PF00731.15 EDO15156.1 - 2.2e-63 212.0 1.4 3.6e-63 211.3 1.0 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EDO15156.1 - 3e-61 205.7 0.0 4.8e-61 205.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EDO15156.1 - 7e-09 35.6 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EDO15156.1 - 3.5e-06 26.4 0.0 8.9e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 EDO15156.1 - 0.00065 19.1 0.0 0.004 16.5 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 EDO15156.1 - 0.0011 18.0 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EDO15156.1 - 0.052 13.7 0.6 13 5.9 0.0 2.9 2 1 1 3 3 3 0 CoA binding domain TrkA_N PF02254.13 EDO15156.1 - 0.075 13.0 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 EDO15156.1 - 0.091 13.2 0.0 0.48 10.8 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ATPgrasp_Ter PF15632.1 EDO15156.1 - 0.11 11.2 0.0 4.9 5.7 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon TPP_enzyme_N PF02776.13 EDO15157.1 - 4.5e-25 88.0 0.0 6.7e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDO15157.1 - 7.1e-18 64.6 0.0 1.6e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDO15157.1 - 6.5e-16 58.2 0.0 1.5e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PRANC PF09372.5 EDO15157.1 - 0.0029 17.5 2.0 0.0029 17.5 1.4 2.9 2 1 0 2 2 2 1 PRANC domain Afi1 PF07792.7 EDO15158.1 - 1.3e-44 151.7 0.5 1.3e-44 151.7 0.3 2.9 3 0 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EDO15158.1 - 4.8e-33 113.2 1.9 1.2e-32 111.9 1.3 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Mito_carr PF00153.22 EDO15159.1 - 7e-46 153.8 4.5 3.7e-15 55.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 EDO15160.1 - 7.6e-08 32.1 0.3 1.9e-07 30.8 0.2 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EDO15160.1 - 2.3e-07 30.3 10.0 2.3e-07 30.3 7.0 1.5 2 0 0 2 2 2 1 Vps5 C terminal like GTP_EFTU PF00009.22 EDO15161.1 - 2e-62 210.0 0.1 2.8e-62 209.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EDO15161.1 - 1.6e-37 127.7 0.0 4.9e-37 126.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EDO15161.1 - 4.7e-21 74.4 0.0 1.5e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EDO15161.1 - 1.4e-13 50.5 0.0 4.1e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EDO15161.1 - 1.8e-11 43.9 0.6 7.5e-11 41.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO15161.1 - 3.4e-05 23.7 0.1 7.7e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SUKH-4 PF14435.1 EDO15161.1 - 0.1 12.2 0.0 0.46 10.1 0.0 2.1 1 0 0 1 1 1 0 SUKH-4 immunity protein ERCC4 PF02732.10 EDO15162.1 - 8.5e-23 80.6 0.1 1.8e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain CbiK PF06180.6 EDO15162.1 - 0.05 12.6 0.2 0.77 8.8 0.0 2.3 2 0 0 2 2 2 0 Cobalt chelatase (CbiK) HHH_8 PF14716.1 EDO15162.1 - 0.098 12.8 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain BAR PF03114.13 EDO15163.1 - 2.4e-61 207.1 6.5 3.1e-61 206.8 4.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EDO15163.1 - 1.1e-10 40.6 0.0 2e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO15163.1 - 2.5e-09 36.5 0.1 4.2e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDO15163.1 - 1.6e-06 27.5 0.0 3.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF755 PF05501.6 EDO15163.1 - 0.1 12.6 1.1 0.2 11.7 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CorA PF01544.13 EDO15163.1 - 0.24 10.3 4.4 4.1 6.3 1.6 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein RhoGAP PF00620.22 EDO15164.1 - 8.8e-33 113.0 0.1 1.1e-20 73.8 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain FANCI_S3 PF14677.1 EDO15164.1 - 0.02 14.3 0.2 0.037 13.4 0.2 1.4 1 0 0 1 1 1 0 FANCI solenoid 3 SSP160 PF06933.6 EDO15164.1 - 1.1 7.0 14.2 3.1 5.6 9.8 1.6 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Iso_dh PF00180.15 EDO15165.1 - 1.1e-102 343.6 0.0 1.2e-102 343.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CoA_binding PF02629.14 EDO15166.1 - 4e-23 81.7 4.9 9.1e-23 80.6 1.5 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EDO15166.1 - 2.7e-22 79.0 0.7 4.3e-22 78.3 0.5 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EDO15166.1 - 6.1e-07 29.1 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EDO15166.1 - 6.4e-05 23.0 0.0 0.00019 21.5 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain GCR1_C PF12550.3 EDO15168.1 - 1.5e-18 66.4 0.9 3.7e-18 65.1 0.7 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Aromatic_hydrox PF11723.3 EDO15168.1 - 0.0046 16.3 0.3 0.012 14.9 0.2 1.7 1 0 0 1 1 1 1 Homotrimeric ring hydroxylase MFS_1 PF07690.11 EDO15169.1 - 8e-35 120.1 40.8 1.1e-34 119.6 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pet20 PF08692.5 EDO15170.1 - 9.2e-49 164.9 0.1 1.4e-48 164.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet20 Band_7 PF01145.20 EDO15171.1 - 4.2e-23 82.1 4.8 7.6e-23 81.3 3.3 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family MARVEL PF01284.18 EDO15172.1 - 1.1e-27 96.5 12.1 1.5e-27 96.1 8.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF3844 PF12955.2 EDO15172.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) ABC2_membrane_3 PF12698.2 EDO15172.1 - 0.31 10.0 10.3 0.35 9.8 4.3 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein BAR_2 PF10455.4 EDO15173.1 - 4.9e-59 199.6 17.7 8.9e-59 198.7 9.8 2.4 2 1 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EDO15173.1 - 7e-06 25.7 4.2 0.00017 21.2 0.6 2.5 3 0 0 3 3 3 2 BAR domain Tape_meas_lam_C PF09718.5 EDO15173.1 - 0.00066 19.5 2.5 0.19 11.6 0.0 2.8 2 1 0 2 2 2 2 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Myb_DNA-bind_5 PF13873.1 EDO15173.1 - 0.021 14.6 0.7 0.39 10.6 0.0 2.5 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain DUF1664 PF07889.7 EDO15173.1 - 0.024 14.4 3.7 0.091 12.5 0.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Tweety PF04906.8 EDO15173.1 - 0.41 9.0 2.0 0.41 8.9 0.1 1.8 2 0 0 2 2 2 0 Tweety Endotoxin_N PF03945.9 EDO15173.1 - 3.6 6.9 14.9 0.5 9.7 0.3 3.1 2 1 0 3 3 3 0 delta endotoxin, N-terminal domain BAR_2 PF10455.4 EDO15174.1 - 6.9e-23 80.9 7.0 9.8e-23 80.4 4.8 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking HC2 PF07382.6 EDO15174.1 - 0.014 15.2 2.3 0.019 14.8 1.6 1.1 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Adeno_terminal PF02459.10 EDO15174.1 - 0.047 11.8 1.5 0.054 11.6 1.1 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Pox_Ag35 PF03286.9 EDO15174.1 - 0.12 11.9 11.1 0.14 11.7 7.7 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.8 EDO15174.1 - 1.5 7.2 7.9 1.7 7.0 5.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NRDE PF05742.7 EDO15175.1 - 7.5e-50 169.7 0.1 9.1e-50 169.4 0.1 1.0 1 0 0 1 1 1 1 NRDE protein RtxA PF07634.6 EDO15175.1 - 0.085 13.1 0.2 0.32 11.3 0.1 2.0 2 0 0 2 2 2 0 RtxA repeat Zip PF02535.17 EDO15176.1 - 0.0047 15.9 10.9 0.0048 15.9 7.6 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter KIAA1328 PF15369.1 EDO15176.1 - 0.33 10.7 18.2 0.42 10.3 12.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 DUF1796 PF08795.5 EDO15176.1 - 3.3 7.3 11.0 5.5 6.5 7.6 1.7 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) RTA1 PF04479.8 EDO15177.1 - 5.2e-63 212.5 10.5 1e-62 211.6 7.3 1.4 1 1 0 1 1 1 1 RTA1 like protein 2TM PF13239.1 EDO15177.1 - 1.7 8.7 5.9 0.52 10.4 0.2 2.8 3 0 0 3 3 3 0 2TM domain zf-DHHC PF01529.15 EDO15177.1 - 2.5 7.4 5.3 1 8.7 0.3 2.4 2 1 0 2 2 2 0 DHHC palmitoyltransferase CBF PF03914.12 EDO15178.1 - 3.5e-45 153.3 0.6 7.2e-45 152.3 0.4 1.6 1 0 0 1 1 1 1 CBF/Mak21 family Lipase_GDSL_3 PF14606.1 EDO15178.1 - 0.026 14.2 0.2 0.089 12.5 0.0 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Retrotrans_gag PF03732.12 EDO15179.1 - 4.5e-07 29.8 0.0 7.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein Zds_C PF08632.5 EDO15180.1 - 1.7e-31 107.3 2.8 3.1e-31 106.5 2.0 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF1892 PF08987.5 EDO15181.1 - 7.1e-48 161.4 5.4 7.8e-48 161.2 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) FA_hydroxylase PF04116.8 EDO15182.1 - 2.5e-10 40.7 19.8 2.5e-10 40.7 13.7 2.0 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EDO15182.1 - 0.035 14.1 0.2 0.067 13.2 0.1 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Kua-UEV1_localn PF10520.4 EDO15182.1 - 2 8.0 11.3 8.6 5.9 0.4 3.2 2 1 1 3 3 3 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain DUF3021 PF11457.3 EDO15182.1 - 3.1 7.7 9.5 19 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Pribosyltran PF00156.22 EDO15183.1 - 6e-18 64.7 0.5 1.6e-17 63.4 0.2 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain PXA PF02194.10 EDO15184.1 - 2.6e-36 124.9 2.3 2.6e-36 124.9 1.6 2.6 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EDO15184.1 - 1.7e-20 73.1 0.1 4.2e-20 71.9 0.1 1.7 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EDO15184.1 - 1.3e-14 53.9 2.9 1.3e-14 53.9 2.0 2.7 2 0 0 2 2 2 1 PX domain Plant_tran PF04827.9 EDO15184.1 - 0.0038 16.6 1.0 1.9 7.8 0.0 3.3 3 0 0 3 3 3 2 Plant transposon protein G-patch PF01585.18 EDO15185.1 - 0.00058 19.5 1.3 0.0048 16.6 1.0 2.7 2 1 0 2 2 2 1 G-patch domain SprA-related PF12118.3 EDO15185.1 - 0.039 13.2 19.6 0.044 13.1 13.6 1.1 1 0 0 1 1 1 0 SprA-related family CDC45 PF02724.9 EDO15185.1 - 0.65 7.9 30.1 0.67 7.9 20.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 EDO15185.1 - 8.5 5.2 11.2 13 4.6 7.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter RRM_1 PF00076.17 EDO15186.1 - 7.9e-42 140.7 1.2 1.4e-17 63.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO15186.1 - 1.1e-37 127.8 0.1 5.5e-14 51.8 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO15186.1 - 3.6e-17 61.9 0.5 9.9e-08 31.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 EDO15186.1 - 1.2e-07 30.8 1.0 1.2e-07 30.8 0.7 2.5 2 0 0 2 2 2 1 Lsm interaction motif Nup35_RRM_2 PF14605.1 EDO15186.1 - 4e-07 29.6 0.0 0.009 15.7 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Pyrophosphatase PF00719.14 EDO15187.1 - 1.1e-50 171.1 0.2 1.4e-50 170.7 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF221 PF02714.10 EDO15188.1 - 1.4e-110 369.2 26.8 3e-110 368.1 18.6 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDO15188.1 - 3.2e-41 140.5 1.8 3.2e-41 140.5 1.2 3.0 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EDO15188.1 - 1.9e-28 98.1 2.0 1.7e-27 95.1 0.1 3.0 3 0 0 3 3 3 1 Phosphate metabolism protein DUF4463 PF14703.1 EDO15188.1 - 2.6e-13 50.2 1.9 5.7e-13 49.1 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Apc4_WD40 PF12894.2 EDO15189.1 - 0.016 14.6 0.0 0.059 12.8 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain NDUF_B5 PF09781.4 EDO15189.1 - 1.1 8.4 12.4 0.16 11.2 0.4 2.6 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Pkinase PF00069.20 EDO15190.1 - 1.3e-68 230.9 0.0 2.3e-68 230.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15190.1 - 3.7e-37 127.8 0.0 7.8e-37 126.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO15190.1 - 0.0042 16.0 0.0 0.026 13.4 0.0 2.1 2 1 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 EDO15190.1 - 0.024 13.9 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ABC1 PF03109.11 EDO15190.1 - 0.039 13.9 0.0 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 ABC1 family StbA PF06406.6 EDO15190.1 - 0.045 12.6 0.1 0.064 12.1 0.1 1.2 1 0 0 1 1 1 0 StbA protein Glycogen_syn PF05693.8 EDO15191.1 - 0 1085.3 0.0 0 1085.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EDO15191.1 - 5.4e-11 42.2 0.0 4.3e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EDO15191.1 - 9.9e-05 22.5 0.0 0.00018 21.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 EDO15191.1 - 0.0072 15.8 0.1 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 Starch synthase catalytic domain Glutaredoxin PF00462.19 EDO15192.1 - 0.03 14.3 0.0 0.23 11.4 0.0 2.7 2 0 0 2 2 2 0 Glutaredoxin IMS PF00817.15 EDO15194.1 - 7.8e-40 136.0 0.0 1.2e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EDO15194.1 - 4e-10 39.6 0.0 9.7e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf-C2H2_6 PF13912.1 EDO15194.1 - 0.057 13.3 0.5 0.15 11.9 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.2 EDO15194.1 - 0.088 13.0 0.6 0.088 13.0 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDO15194.1 - 0.09 12.9 0.9 0.24 11.6 0.6 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding IMS_HHH PF11798.3 EDO15194.1 - 0.1 12.7 0.0 0.35 11.0 0.0 2.0 1 1 0 1 1 1 0 IMS family HHH motif Ribosomal_L11_N PF03946.9 EDO15195.1 - 1.1e-11 43.9 0.5 4.6e-11 42.0 0.1 2.0 2 1 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EDO15195.1 - 2.2e-10 40.4 0.1 3.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain AMP-binding PF00501.23 EDO15196.1 - 8.1e-65 218.8 0.0 1.1e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EB1 PF03271.12 EDO15197.1 - 3.2e-20 71.8 0.1 9.5e-20 70.3 0.1 1.9 1 1 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EDO15197.1 - 2.1e-06 27.7 0.2 4.5e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain zf-C4H2 PF10146.4 EDO15197.1 - 0.012 15.6 2.2 0.021 14.8 1.5 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Peptidase_M41 PF01434.13 EDO15198.1 - 1.7e-75 253.1 0.0 2.5e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EDO15198.1 - 1.9e-43 147.8 0.0 8.5e-43 145.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EDO15198.1 - 3.6e-05 23.9 1.3 0.00011 22.3 0.9 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EDO15198.1 - 0.00032 20.4 0.0 0.0013 18.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EDO15198.1 - 0.00037 21.3 0.0 0.0016 19.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO15198.1 - 0.00071 19.7 0.4 0.088 12.9 0.1 3.0 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EDO15198.1 - 0.0021 17.9 0.0 0.28 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EDO15198.1 - 0.0032 16.2 0.0 0.0077 14.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EDO15198.1 - 0.0042 16.1 0.0 0.0081 15.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDO15198.1 - 0.0048 16.6 0.8 0.015 15.0 0.5 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EDO15198.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EDO15198.1 - 0.017 15.0 0.1 0.049 13.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EDO15198.1 - 0.021 13.8 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 EDO15198.1 - 0.024 14.5 1.8 0.094 12.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EDO15198.1 - 0.069 12.5 1.1 0.21 10.9 0.4 2.1 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EDO15198.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO15198.1 - 0.64 10.3 0.0 0.64 10.3 0.0 3.4 4 1 0 4 4 2 0 AAA domain HMG_box PF00505.14 EDO15199.1 - 4.5e-13 49.2 4.2 1.8e-12 47.3 2.9 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO15199.1 - 3.5e-05 24.0 0.2 9.5e-05 22.6 0.1 1.8 1 1 0 1 1 1 1 HMG-box domain TFIIA PF03153.8 EDO15199.1 - 0.21 11.4 7.5 0.23 11.3 5.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med22 PF06179.7 EDO15200.1 - 3.1e-24 85.0 1.6 3.7e-24 84.8 1.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex BRO1 PF03097.13 EDO15200.1 - 0.048 12.3 0.2 0.054 12.2 0.1 1.1 1 0 0 1 1 1 0 BRO1-like domain Pox_Ag35 PF03286.9 EDO15200.1 - 0.069 12.6 1.0 0.094 12.2 0.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MIS13 PF08202.6 EDO15201.1 - 4.7e-65 219.6 17.4 4.7e-65 219.6 12.1 1.4 2 0 0 2 2 2 1 Mis12-Mtw1 protein family WD40 PF00400.27 EDO15203.1 - 1.8e-08 33.9 12.2 0.00057 19.6 0.3 6.8 8 0 0 8 8 8 2 WD domain, G-beta repeat PQQ_2 PF13360.1 EDO15203.1 - 7.9e-05 22.2 0.0 0.00068 19.1 0.0 2.2 1 1 0 1 1 1 1 PQQ-like domain Apc4_WD40 PF12894.2 EDO15203.1 - 9.3e-05 21.8 0.0 0.0034 16.8 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.1 EDO15203.1 - 0.0027 17.9 0.3 0.11 12.7 0.0 3.0 3 0 0 3 3 3 1 PQQ-like domain PQQ PF01011.16 EDO15203.1 - 0.039 13.4 0.9 0.28 10.7 0.0 2.8 4 0 0 4 4 4 0 PQQ enzyme repeat Lum_binding PF00677.12 EDO15204.1 - 2e-53 178.2 7.6 3e-27 94.3 0.6 2.2 2 0 0 2 2 2 2 Lumazine binding domain Ribosomal_L2_C PF03947.13 EDO15205.1 - 2.5e-41 140.5 2.5 4.1e-41 139.8 1.7 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDO15205.1 - 2e-13 50.1 0.1 4.7e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Peptidase_C48 PF02902.14 EDO15206.1 - 1.7e-35 122.6 8.2 1.7e-35 122.6 5.7 2.4 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain RINGv PF12906.2 EDO15207.1 - 1e-15 57.4 6.9 1.8e-15 56.6 4.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EDO15207.1 - 0.0072 16.1 5.4 0.015 15.0 3.7 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EDO15207.1 - 0.63 10.0 4.1 1.3 8.9 2.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Not1 PF04054.10 EDO15208.1 - 1.1e-140 468.8 5.2 1.1e-140 468.8 3.6 3.4 4 0 0 4 4 4 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EDO15208.1 - 1.3e-42 145.0 6.0 1.3e-42 145.0 4.1 2.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3819) CDC50 PF03381.10 EDO15209.1 - 1.1e-95 320.0 0.9 1.3e-95 319.7 0.6 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Flocculin PF00624.13 EDO15210.1 - 4.5e-130 423.3 462.0 1e-13 50.8 13.3 125.4 77 4 41 128 128 128 25 Flocculin repeat Helicase_C PF00271.26 EDO15212.1 - 3.1e-15 55.7 0.0 6.9e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO15212.1 - 7.5e-09 35.3 0.0 1.2e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase UAA PF08449.6 EDO15213.1 - 3.3e-15 55.8 27.9 4.1e-15 55.4 19.4 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EDO15213.1 - 2.3e-09 37.0 10.5 2.3e-09 37.0 7.3 2.7 1 1 2 3 3 3 1 Triose-phosphate Transporter family Nse5 PF08691.5 EDO15214.1 - 1.7e-81 274.2 35.3 2.1e-81 273.9 24.5 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 NIF3 PF01784.13 EDO15216.1 - 1.3e-63 214.7 0.1 1.6e-63 214.4 0.1 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 EDO15217.1 - 7.7e-20 70.6 0.0 8.6e-20 70.4 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Fucose_iso_N1 PF07881.7 EDO15217.1 - 0.024 14.1 0.1 0.03 13.8 0.1 1.0 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain Kinesin PF00225.18 EDO15218.1 - 3.1e-111 371.3 5.8 3.1e-111 371.3 4.0 2.4 2 2 0 2 2 2 1 Kinesin motor domain IMD PF08397.6 EDO15218.1 - 0.0012 18.1 6.8 0.0028 16.9 4.7 1.6 1 0 0 1 1 1 1 IRSp53/MIM homology domain Cyclin PF08613.6 EDO15219.1 - 1.2e-05 25.7 0.0 2.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin EHN PF06441.7 EDO15219.1 - 0.081 12.8 0.2 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Imm2 PF14426.1 EDO15221.1 - 0.3 11.0 1.3 1.3 9.0 0.0 2.9 4 0 0 4 4 4 0 Immunity protein Imm2 Ras PF00071.17 EDO15222.1 - 1.1e-61 206.9 0.2 1.3e-61 206.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO15222.1 - 1.1e-19 71.0 0.0 1.8e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO15222.1 - 1.4e-13 50.4 0.0 1.9e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDO15222.1 - 6.9e-07 29.2 0.0 1e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDO15222.1 - 4.8e-05 22.8 0.1 0.0001 21.8 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 EDO15222.1 - 0.00037 19.6 0.1 0.0006 18.9 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.7 EDO15222.1 - 0.00044 19.4 0.1 0.00059 19.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EDO15222.1 - 0.00059 19.3 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EDO15222.1 - 0.0016 17.6 0.1 0.0066 15.6 0.0 1.8 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EDO15222.1 - 0.0035 16.5 0.6 0.008 15.3 0.1 1.9 2 1 0 2 2 2 1 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 EDO15222.1 - 0.0051 15.8 0.0 0.007 15.3 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 EDO15222.1 - 0.0061 16.5 0.4 0.033 14.1 0.3 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EDO15222.1 - 0.0062 16.6 0.1 0.012 15.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 EDO15222.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 EDO15222.1 - 0.066 13.5 0.8 0.15 12.3 0.5 1.8 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.13 EDO15222.1 - 0.068 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B TraG_N PF07916.6 EDO15222.1 - 0.077 11.4 0.2 0.096 11.1 0.2 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region CHZ PF09649.5 EDO15223.1 - 7.6e-19 66.6 1.6 7.6e-19 66.6 1.1 2.5 3 0 0 3 3 3 1 Histone chaperone domain CHZ DUF572 PF04502.8 EDO15223.1 - 6.8 5.8 17.4 8.4 5.5 12.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) LSM PF01423.17 EDO15224.1 - 1.2e-17 63.2 0.7 2.1e-17 62.4 0.5 1.4 1 0 0 1 1 1 1 LSM domain BLVR PF06375.6 EDO15224.1 - 0.38 10.5 8.0 0.53 10.1 5.5 1.3 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) zf-C2H2 PF00096.21 EDO15225.1 - 6.9e-11 41.8 11.2 1.9e-05 24.6 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO15225.1 - 1.6e-08 34.2 8.4 0.00071 19.7 0.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO15225.1 - 1.7e-06 28.0 4.3 1.7e-06 28.0 3.0 3.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDO15225.1 - 0.013 15.6 1.7 2.2 8.5 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Clathrin PF00637.15 EDO15226.1 - 8.2e-190 622.0 67.2 3.3e-34 117.5 1.6 8.7 10 0 0 10 10 10 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EDO15226.1 - 4.9e-26 90.3 0.2 2.6e-25 88.1 0.1 2.4 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EDO15226.1 - 1.7e-17 62.4 3.9 0.00011 22.2 0.1 5.8 5 0 0 5 5 5 5 Clathrin propeller repeat Clathrin-link PF09268.5 EDO15226.1 - 0.0013 17.6 2.4 0.003 16.5 0.1 2.6 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_12 PF13424.1 EDO15226.1 - 0.017 15.0 1.4 3.2 7.7 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat RVT_2 PF07727.9 EDO15227.1 - 1.8e-41 141.7 0.1 3.4e-41 140.8 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EDO15227.1 - 0.00018 21.8 0.0 0.0005 20.4 0.0 1.7 1 0 0 1 1 1 1 RNase H Helicase_C PF00271.26 EDO15228.1 - 1.6e-11 43.8 0.1 2.4e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cnd1 PF12717.2 EDO15229.1 - 0.0018 18.1 0.2 2 8.2 0.0 2.6 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EDO15229.1 - 0.0023 17.3 0.1 0.072 12.4 0.1 2.8 1 1 1 2 2 2 1 CLASP N terminal HEAT PF02985.17 EDO15229.1 - 0.0051 16.7 0.0 1.5 9.0 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EDO15229.1 - 0.025 14.9 0.0 0.46 10.8 0.0 2.8 1 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region RRM_1 PF00076.17 EDO15230.1 - 2.7e-18 65.3 0.0 6.6e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO15230.1 - 1.4e-12 47.4 0.0 3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO15230.1 - 5.8e-09 35.6 0.1 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDO15230.1 - 0.034 13.8 0.0 0.16 11.7 0.0 2.2 1 1 0 1 1 1 0 Limkain b1 Syja_N PF02383.13 EDO15231.1 - 4e-91 305.0 0.4 5.7e-91 304.6 0.3 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EDO15231.1 - 1.1e-25 91.0 0.1 2.8e-25 89.6 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family KxDL PF10241.4 EDO15231.1 - 0.068 13.0 0.0 1 9.2 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein PAT1 PF09770.4 EDO15231.1 - 6.4 4.8 11.0 9.6 4.2 7.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SNARE PF05739.14 EDO15232.1 - 2.7e-16 58.9 4.2 6.7e-16 57.7 2.9 1.7 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.16 EDO15232.1 - 7.9e-06 25.3 5.5 2.3e-05 23.8 3.8 1.9 1 0 0 1 1 1 1 Synaptobrevin Syntaxin_2 PF14523.1 EDO15232.1 - 0.0029 17.6 4.2 0.0029 17.6 2.9 3.0 2 2 0 2 2 2 1 Syntaxin-like protein Laminin_II PF06009.7 EDO15232.1 - 0.0069 16.1 3.5 0.0069 16.1 2.4 2.7 2 1 1 3 3 3 1 Laminin Domain II LPP PF04728.8 EDO15232.1 - 0.015 15.0 3.5 0.036 13.8 2.4 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper Spidroin_MaSp PF11260.3 EDO15232.1 - 0.018 15.1 1.8 0.045 13.8 1.2 1.7 1 1 0 1 1 1 0 Major ampullate spidroin 1 and 2 DUF3753 PF12575.3 EDO15232.1 - 0.019 14.7 1.5 0.058 13.1 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) ODV-E18 PF10717.4 EDO15232.1 - 0.025 14.0 0.9 0.06 12.7 0.6 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 OppC_N PF12911.2 EDO15232.1 - 0.065 12.6 7.3 0.17 11.2 5.1 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4519 PF15012.1 EDO15232.1 - 0.084 12.7 5.8 0.72 9.8 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4519) MCPsignal PF00015.16 EDO15232.1 - 0.13 11.7 9.4 0.015 14.8 2.5 2.1 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Equine_IAV_S2 PF06502.6 EDO15232.1 - 5 7.0 7.6 1.4 8.8 0.3 2.7 3 0 0 3 3 3 0 Equine infectious anaemia virus S2 protein DUF912 PF06024.7 EDO15232.1 - 9.7 6.3 15.6 0.092 12.8 2.6 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Aa_trans PF01490.13 EDO15233.1 - 4.6e-100 334.9 30.4 5.6e-100 334.6 21.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_C37 PF05416.7 EDO15234.1 - 0.088 11.0 0.0 0.099 10.9 0.0 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Ras PF00071.17 EDO15235.1 - 1.3e-56 190.4 0.3 2.3e-56 189.6 0.2 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO15235.1 - 2.3e-21 76.5 0.1 5.2e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO15235.1 - 7.1e-08 31.8 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO15235.1 - 1.3e-06 27.9 0.4 6.8e-06 25.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO15235.1 - 4.2e-05 23.4 0.0 8.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 EDO15235.1 - 0.13 11.6 0.0 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain ING PF12998.2 EDO15236.1 - 4.8e-20 71.8 0.5 1.1e-19 70.6 0.0 1.9 3 0 0 3 3 3 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EDO15236.1 - 2.9e-09 36.4 6.8 4.8e-09 35.7 4.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EDO15236.1 - 0.024 13.9 1.4 0.047 12.9 1.0 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.1 EDO15236.1 - 0.047 13.8 0.2 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain IF2_N PF04760.10 EDO15236.1 - 0.081 12.5 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Glypican PF01153.14 EDO15236.1 - 2.8 6.4 11.5 4.4 5.8 7.7 1.4 1 1 0 1 1 1 0 Glypican SOG2 PF10428.4 EDO15236.1 - 8 4.9 17.9 11 4.5 12.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_transf_15 PF01793.11 EDO15237.1 - 3.1e-137 456.9 22.2 3.8e-137 456.6 15.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 EDO15238.1 - 8.6e-99 330.6 19.6 1e-98 330.3 13.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Lac_bphage_repr PF06543.7 EDO15238.1 - 0.11 12.0 0.1 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor PP2C PF00481.16 EDO15240.1 - 1.7e-39 135.7 0.1 4.1e-39 134.5 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C Ras PF00071.17 EDO15242.1 - 1.7e-59 199.8 0.0 2e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO15242.1 - 1.5e-18 67.3 0.0 2.5e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO15242.1 - 3.9e-17 62.0 0.0 4.6e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDO15242.1 - 1.1e-06 27.9 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO15242.1 - 3.8e-06 26.4 0.0 6.7e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO15242.1 - 5e-05 23.2 0.0 8.5e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDO15242.1 - 0.12 11.5 0.0 0.68 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NST1 PF13945.1 EDO15243.1 - 4.6e-06 26.8 0.4 4.6e-06 26.8 0.3 6.9 5 1 1 6 6 6 2 Salt tolerance down-regulator Ras PF00071.17 EDO15244.1 - 9.6e-50 168.1 0.0 1.1e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO15244.1 - 5.8e-14 52.5 0.0 7.9e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO15244.1 - 6.6e-08 31.9 0.0 9e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 EDO15244.1 - 0.0008 18.9 0.0 1.1 8.6 0.0 2.4 2 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EDO15244.1 - 0.018 14.2 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.1 EDO15244.1 - 0.034 14.0 0.1 0.054 13.4 0.1 1.4 1 1 0 1 1 1 0 AAA domain EMP24_GP25L PF01105.19 EDO15245.1 - 2.5e-43 147.9 0.1 3.2e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PIP5K PF01504.13 EDO15246.1 - 3.2e-83 278.6 4.8 8.8e-83 277.2 3.3 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Aminotran_5 PF00266.14 EDO15247.1 - 1.5e-11 43.6 0.0 8.3e-11 41.2 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Acatn PF13000.2 EDO15248.1 - 1.6e-203 677.2 14.8 1.9e-203 676.9 10.3 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Scs3p PF10261.4 EDO15249.1 - 1.6e-75 253.2 6.4 2.5e-75 252.6 4.5 1.3 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM CRAL_TRIO_2 PF13716.1 EDO15249.1 - 0.88 9.4 4.8 1.1 9.2 0.2 2.4 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain Med31 PF05669.7 EDO15250.1 - 1.4e-32 111.4 0.4 1.8e-32 111.1 0.3 1.1 1 0 0 1 1 1 1 SOH1 CPSase_L_D2 PF02786.12 EDO15251.1 - 6.9e-84 280.3 0.4 1.3e-83 279.4 0.3 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EDO15251.1 - 4.1e-66 222.1 0.0 7.7e-66 221.2 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EDO15251.1 - 7.9e-36 122.5 0.0 2.2e-35 121.0 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EDO15251.1 - 2.3e-30 104.7 0.0 9.2e-30 102.7 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EDO15251.1 - 1e-26 94.0 0.1 2.6e-26 92.7 0.1 1.7 1 0 0 1 1 1 1 HMGL-like ATPgrasp_Ter PF15632.1 EDO15251.1 - 1.6e-20 73.1 0.0 7.6e-20 70.9 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EDO15251.1 - 1.8e-17 62.7 4.1 1.8e-17 62.7 2.8 2.7 3 0 0 3 3 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EDO15251.1 - 7.4e-16 58.4 0.2 1.4e-15 57.5 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EDO15251.1 - 7.1e-11 41.6 1.0 2.5e-05 23.8 0.1 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EDO15251.1 - 9.1e-07 28.3 0.1 1.9e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDO15251.1 - 1.4e-06 27.8 0.0 2.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 EDO15251.1 - 8.7e-06 25.2 0.3 0.033 13.5 0.1 2.5 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 EDO15251.1 - 1.3e-05 25.0 0.1 3.6e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EDO15251.1 - 1.7e-05 24.3 0.0 5e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 EDO15251.1 - 0.00076 19.7 1.6 0.019 15.3 0.4 3.5 2 1 1 3 3 3 1 HlyD family secretion protein HlyD_2 PF12700.2 EDO15251.1 - 0.0062 15.7 0.9 1.6 7.7 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.1 EDO15251.1 - 0.0078 15.9 2.9 0.083 12.6 0.7 2.8 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain DASH_Duo1 PF08651.5 EDO15252.1 - 1e-28 98.6 0.3 2.8e-28 97.3 0.2 1.7 1 0 0 1 1 1 1 DASH complex subunit Duo1 BCDHK_Adom3 PF10436.4 EDO15253.1 - 6.7e-33 113.5 1.0 6.7e-33 113.5 0.7 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EDO15253.1 - 9.1e-10 38.2 0.0 1.3e-08 34.4 0.0 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDO15253.1 - 0.0039 16.8 0.0 0.007 16.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UQ_con PF00179.21 EDO15254.1 - 1.4e-50 170.3 0.1 1.7e-50 170.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO15254.1 - 2.3e-06 27.3 0.0 3.5e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDO15254.1 - 0.0072 16.2 0.2 0.023 14.5 0.1 1.8 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EDO15254.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain Nucleoplasmin PF03066.10 EDO15254.1 - 3.6 7.1 9.5 4.8 6.6 6.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin Cyclin_N PF00134.18 EDO15256.1 - 2.8e-45 152.9 0.5 7e-45 151.6 0.3 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDO15256.1 - 4.7e-29 100.7 0.1 1.4e-28 99.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain MutS_V PF00488.16 EDO15257.1 - 3e-55 187.1 0.0 8.2e-55 185.7 0.0 1.8 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDO15257.1 - 6.3e-31 107.7 0.1 1.4e-30 106.6 0.1 1.6 1 0 0 1 1 1 1 MutS domain III AAA_22 PF13401.1 EDO15257.1 - 0.0097 16.0 0.3 0.032 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDO15257.1 - 0.33 10.8 0.0 0.33 10.8 0.0 3.2 5 0 0 5 5 5 0 AAA domain Sas10 PF09368.5 EDO15258.1 - 2.5e-30 104.4 11.4 2.5e-30 104.4 7.9 2.2 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EDO15258.1 - 2.5e-10 40.3 1.7 1e-09 38.4 1.1 2.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family RNA_pol_Rpc4 PF05132.9 EDO15259.1 - 7.6e-34 116.5 2.8 7.6e-34 116.5 2.0 2.8 3 0 0 3 3 3 1 RNA polymerase III RPC4 APG9 PF04109.11 EDO15260.1 - 4.3e-161 535.9 7.6 5.7e-161 535.5 5.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 MFS_1 PF07690.11 EDO15261.1 - 3.1e-26 91.9 37.4 3.1e-26 91.9 25.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO15261.1 - 0.16 10.5 35.4 2.8 6.4 7.2 3.8 2 2 0 2 2 2 0 Sugar (and other) transporter Nop14 PF04147.7 EDO15262.1 - 2.3e-226 753.6 79.2 3e-128 429.1 15.1 2.0 1 1 1 2 2 2 2 Nop14-like family SURF6 PF04935.7 EDO15263.1 - 3.5e-54 183.3 51.9 3.5e-54 183.3 36.0 3.2 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EDO15263.1 - 7.9e-19 67.5 1.9 7.9e-19 67.5 1.3 7.5 6 1 0 6 6 6 2 60S ribosome biogenesis protein Rrp14 zf-CHY PF05495.7 EDO15264.1 - 1.2e-14 54.2 21.8 1.6e-14 53.8 15.1 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-Sec23_Sec24 PF04810.10 EDO15264.1 - 0.24 11.0 0.4 0.24 11.0 0.3 3.0 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Cytochrome_C7 PF14522.1 EDO15264.1 - 2 8.1 14.0 3.1 7.4 9.4 1.8 1 1 0 1 1 1 0 Cytochrome c7 G-alpha PF00503.15 EDO15265.1 - 2.2e-116 388.7 5.4 2.6e-116 388.5 3.8 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EDO15265.1 - 4.3e-13 48.8 0.4 1.5e-09 37.3 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EDO15265.1 - 0.065 13.7 0.0 0.61 10.6 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein Cyto_heme_lyase PF01265.12 EDO15266.1 - 7.2e-83 278.1 0.6 8.8e-83 277.8 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase zf-Tim10_DDP PF02953.10 EDO15267.1 - 1.2e-23 82.1 3.3 1.4e-23 81.9 2.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EDO15267.1 - 0.0046 16.4 2.4 0.0058 16.0 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) YopD PF05844.7 EDO15267.1 - 0.077 12.0 0.5 0.092 11.7 0.4 1.0 1 0 0 1 1 1 0 YopD protein Flavoprotein PF02441.14 EDO15268.1 - 1.4e-43 147.6 0.2 3.3e-43 146.4 0.1 1.7 1 0 0 1 1 1 1 Flavoprotein Hemagglutinin PF00509.13 EDO15268.1 - 0.0095 14.1 1.2 0.013 13.7 0.8 1.1 1 0 0 1 1 1 1 Haemagglutinin CKAP2_C PF15297.1 EDO15268.1 - 0.08 11.7 7.7 0.038 12.8 3.1 2.0 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus Tim54 PF11711.3 EDO15268.1 - 0.36 9.3 4.5 0.71 8.3 3.1 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TFIIA PF03153.8 EDO15268.1 - 2.1 8.1 51.1 5.6 6.7 35.3 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_Ag35 PF03286.9 EDO15268.1 - 4.2 6.8 23.8 11 5.5 16.5 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Corona_nucleoca PF00937.13 EDO15269.1 - 0.1 11.5 10.7 0.073 12.0 5.6 1.8 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Mid2 PF04478.7 EDO15270.1 - 3.1e-53 179.3 3.7 3.1e-53 179.3 2.5 2.1 2 1 0 2 2 2 1 Mid2 like cell wall stress sensor Podoplanin PF05808.6 EDO15270.1 - 0.35 10.4 7.9 0.036 13.6 1.2 2.2 2 0 0 2 2 2 0 Podoplanin NOA36 PF06524.7 EDO15270.1 - 0.66 9.1 8.9 0.85 8.8 6.2 1.2 1 0 0 1 1 1 0 NOA36 protein COX14 PF14880.1 EDO15271.1 - 5.4e-26 89.9 0.7 6e-26 89.8 0.5 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Bac_rhamnosid_N PF08531.5 EDO15271.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Rtf2 PF04641.7 EDO15272.1 - 6.2e-33 114.0 3.3 1.8e-32 112.5 2.3 1.6 1 1 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EDO15272.1 - 0.034 13.6 0.5 0.79 9.2 0.4 2.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-CCCH PF00642.19 EDO15273.1 - 4.5e-09 35.7 12.3 4.7e-05 22.9 0.4 2.8 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EDO15273.1 - 5.9e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO15273.1 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.21 EDO15274.1 - 1.3e-58 197.3 0.0 1.7e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO15274.1 - 3.8e-09 35.7 0.8 6.9e-09 34.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Prefoldin PF02996.12 EDO15275.1 - 4.6e-25 87.5 6.2 6e-25 87.2 4.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF2989 PF11207.3 EDO15275.1 - 0.095 12.1 2.1 6.2 6.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) DUF406 PF04175.7 EDO15275.1 - 0.29 11.6 0.2 0.29 11.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF406) Asn_synthase PF00733.16 EDO15276.1 - 3.1e-45 154.6 0.0 4.9e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EDO15276.1 - 2.3e-13 49.9 0.1 2.3e-11 43.4 0.0 3.1 3 1 0 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EDO15276.1 - 5.3e-08 32.8 0.0 1.9e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EDO15276.1 - 0.0081 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein VPS9 PF02204.13 EDO15277.1 - 6.7e-27 93.5 0.0 1.5e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EDO15277.1 - 3.4e-10 39.2 0.0 7.1e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain TFIID-18kDa PF02269.11 EDO15278.1 - 5.8e-31 106.1 0.0 8.5e-31 105.6 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 EDO15278.1 - 0.0025 17.8 0.0 0.008 16.2 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EDO15278.1 - 0.032 13.9 0.0 0.083 12.6 0.0 1.6 2 0 0 2 2 2 0 Bromodomain associated MTS PF05175.9 EDO15278.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF1717 PF05414.6 EDO15278.1 - 0.18 12.2 0.0 0.18 12.2 0.0 1.7 2 0 0 2 2 2 0 Viral domain of unknown function (DUF1717) Phyto_Pns9_10 PF05878.6 EDO15278.1 - 0.47 9.4 8.3 0.55 9.1 5.8 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 NOA36 PF06524.7 EDO15278.1 - 3.5 6.7 13.2 4.2 6.5 9.2 1.2 1 0 0 1 1 1 0 NOA36 protein Fungal_trans_2 PF11951.3 EDO15279.1 - 6.7e-103 344.2 6.5 9.5e-103 343.7 4.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO15279.1 - 1.8e-09 37.3 7.5 3.8e-09 36.3 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuclease_3 PF00636.21 EDO15280.1 - 1.4e-17 64.1 0.0 1.4e-17 64.1 0.0 2.5 2 1 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.20 EDO15280.1 - 9.5e-16 58.1 0.0 3.6e-07 30.6 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EDO15280.1 - 2.3e-15 56.6 0.2 7.9e-15 54.9 0.0 2.0 1 1 1 2 2 2 1 Ribonuclease-III-like CaMKII_AD PF08332.5 EDO15280.1 - 0.0086 15.9 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II Association MFS_1 PF07690.11 EDO15281.1 - 2.9e-40 138.0 21.6 4.5e-40 137.4 15.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO15281.1 - 5.6e-10 38.3 11.7 8e-10 37.8 8.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter OPT PF03169.10 EDO15282.1 - 3.3e-163 544.4 46.6 3.7e-163 544.2 32.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein rve PF00665.21 EDO15283.1 - 8.5e-18 64.6 0.0 2.5e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 EDO15283.1 - 0.0083 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDO15284.1 - 9.2e-09 34.8 0.0 1.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF3953 PF13129.1 EDO15285.1 - 6.2 6.5 6.6 0.56 9.8 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3953) DUF4434 PF14488.1 EDO15286.1 - 0.012 15.3 0.1 0.036 13.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) DUF3996 PF13161.1 EDO15287.1 - 0.0043 16.6 0.2 0.0091 15.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3996) HATPase_c_3 PF13589.1 EDO15287.1 - 0.028 14.0 0.6 0.069 12.8 0.4 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Aldo_ket_red PF00248.16 EDO15289.1 - 7.9e-62 208.6 0.0 9e-62 208.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3533 PF12051.3 EDO15290.1 - 6.1e-137 456.4 20.2 7.4e-137 456.1 14.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.7 EDO15290.1 - 0.37 10.4 0.1 0.37 10.4 0.1 2.4 3 0 0 3 3 3 0 CDR ABC transporter Flavodoxin_2 PF02525.12 EDO15291.1 - 2.1e-51 174.2 0.0 2.6e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EDO15291.1 - 1.6e-12 47.1 0.0 3.6e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 EDO15291.1 - 6.2e-05 22.3 0.0 0.00016 21.0 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin Zn_clus PF00172.13 EDO15294.1 - 6.8e-08 32.3 12.3 1.4e-07 31.3 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RrnaAD PF00398.15 EDO15295.1 - 7e-66 221.9 0.0 8.2e-66 221.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EDO15295.1 - 8.8e-10 38.6 0.0 1.4e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO15295.1 - 8.4e-06 26.3 0.0 1.6e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO15295.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EDO15295.1 - 0.00034 20.0 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 EDO15295.1 - 0.00068 19.2 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.15 EDO15295.1 - 0.001 18.1 0.0 0.0026 16.8 0.0 1.5 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EDO15295.1 - 0.0027 17.4 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO15295.1 - 0.0032 17.0 0.0 0.0065 16.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EDO15295.1 - 0.0044 16.2 0.1 0.044 12.9 0.0 2.2 3 0 0 3 3 3 1 O-methyltransferase Methyltransf_12 PF08242.7 EDO15295.1 - 0.013 15.9 0.0 0.033 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EDO15295.1 - 0.015 14.4 0.1 0.095 11.7 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.11 EDO15295.1 - 0.018 13.9 0.2 0.46 9.3 0.0 2.0 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase UPF0158 PF03682.8 EDO15295.1 - 0.13 11.8 0.8 0.25 10.9 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) PI-PLC-X PF00388.14 EDO15296.1 - 3e-46 156.4 0.0 6.7e-46 155.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EDO15296.1 - 5.5e-37 126.3 0.0 2.2e-36 124.4 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EDO15296.1 - 2e-06 27.7 1.5 2.8e-06 27.2 0.1 2.0 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.1 EDO15296.1 - 8.6e-05 22.6 1.2 0.0035 17.4 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EDO15296.1 - 0.00014 20.9 0.1 0.0022 17.1 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EDO15296.1 - 0.00025 20.6 0.1 0.031 13.8 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair C2 PF00168.25 EDO15296.1 - 0.028 14.2 0.1 0.14 12.0 0.0 2.3 2 0 0 2 2 2 0 C2 domain EF-hand_5 PF13202.1 EDO15296.1 - 0.033 13.5 0.1 0.081 12.3 0.1 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EDO15296.1 - 0.069 13.0 0.4 0.38 10.7 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain Helicase_C PF00271.26 EDO15297.1 - 6.3e-15 54.8 0.0 1.5e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3953 PF13129.1 EDO15298.1 - 1.6 8.4 4.8 0.56 9.8 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3953) Spt20 PF12090.3 EDO15300.1 - 9.3e-55 184.7 9.3 9.3e-55 184.7 6.5 5.1 3 2 0 3 3 3 1 Spt20 family PEX11 PF05648.9 EDO15301.1 - 2.8e-64 216.4 6.0 3.2e-64 216.2 4.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sld5 PF05916.6 EDO15302.1 - 3.5e-15 56.2 0.0 4.6e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein RRM_5 PF13893.1 EDO15303.1 - 4.7e-11 42.3 0.4 9.1e-11 41.4 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO15303.1 - 0.00043 19.8 0.7 0.00099 18.7 0.5 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DMRL_synthase PF00885.14 EDO15304.1 - 1.2e-43 148.2 0.0 1.5e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase ParBc PF02195.13 EDO15304.1 - 0.13 12.3 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 ParB-like nuclease domain Hist_deacetyl PF00850.14 EDO15305.1 - 8.5e-81 271.6 0.3 1.3e-80 271.0 0.0 1.3 2 0 0 2 2 2 1 Histone deacetylase domain DnaJ PF00226.26 EDO15306.1 - 1.2e-05 24.8 0.2 2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EDO15306.1 - 0.011 15.4 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 Pam16 CDC50 PF03381.10 EDO15308.1 - 8.8e-91 303.9 1.0 8.8e-91 303.9 0.7 2.0 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF943 PF06092.7 EDO15308.1 - 0.052 12.8 0.6 0.11 11.7 0.4 1.5 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) PBP1_TM PF14812.1 EDO15308.1 - 5.4 7.3 11.6 2.4 8.5 5.8 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Na_Ca_ex PF01699.19 EDO15310.1 - 4.8e-26 91.0 23.6 4.1e-17 62.0 5.3 4.4 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EDO15310.1 - 1.5e-15 57.3 8.1 1.5e-15 57.3 5.6 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF307) DUF2371 PF10177.4 EDO15310.1 - 0.094 12.5 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) IF4E PF01652.13 EDO15311.1 - 3.3e-58 195.8 0.6 3.9e-58 195.6 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4240 PF14024.1 EDO15311.1 - 0.027 14.3 0.1 0.043 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4240) Abhydrolase_5 PF12695.2 EDO15312.1 - 7.8e-18 64.6 0.0 1.1e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO15312.1 - 2.7e-13 50.3 0.0 2.8e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO15312.1 - 1.4e-11 44.4 0.1 0.00012 21.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 EDO15312.1 - 4.4e-06 26.2 0.0 6.2e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EDO15312.1 - 2.8e-05 23.4 0.0 9.5e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EDO15312.1 - 0.00035 20.3 0.0 0.03 14.0 0.0 2.3 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EDO15312.1 - 0.011 15.1 0.2 0.49 9.7 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 EDO15312.1 - 0.026 13.0 0.0 3.8 5.9 0.0 2.4 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) DUF1057 PF06342.7 EDO15312.1 - 0.076 11.8 0.0 0.096 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S15 PF02129.13 EDO15312.1 - 0.087 12.2 0.0 7.8 5.8 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EDO15312.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase PAE PF03283.8 EDO15312.1 - 0.12 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase WD40 PF00400.27 EDO15313.1 - 1.2e-18 66.1 0.2 2.5e-08 33.4 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 EDO15313.1 - 0.00052 19.7 4.5 0.00052 19.7 3.1 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EDO15313.1 - 0.00057 19.9 4.2 0.0015 18.5 2.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EDO15313.1 - 0.0099 15.8 4.6 0.0099 15.8 3.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO15313.1 - 0.4 10.3 8.3 0.086 12.5 2.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ASF1_hist_chap PF04729.8 EDO15315.1 - 9.8e-68 226.6 0.1 1.4e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone CENP-T PF15511.1 EDO15315.1 - 0.077 12.2 25.4 0.098 11.8 17.6 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EDO15315.1 - 0.36 8.6 46.1 0.52 8.1 32.0 1.2 1 0 0 1 1 1 0 Nop14-like family SUN PF03856.8 EDO15316.1 - 8.4e-102 339.7 15.4 8.4e-102 339.7 10.6 1.5 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) zf-MYND PF01753.13 EDO15316.1 - 0.31 10.9 3.5 0.66 9.9 2.5 1.5 1 0 0 1 1 1 0 MYND finger Med3 PF11593.3 EDO15316.1 - 1.8 7.6 12.0 2.3 7.3 8.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Macoilin PF09726.4 EDO15316.1 - 3.4 5.8 6.5 3.9 5.6 4.5 1.1 1 0 0 1 1 1 0 Transmembrane protein His_Phos_1 PF00300.17 EDO15317.1 - 2.4e-28 99.2 0.2 2.9e-28 98.9 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lectin_leg-like PF03388.8 EDO15318.1 - 4.7e-09 35.7 0.2 7.4e-06 25.2 0.1 2.3 2 0 0 2 2 2 2 Legume-like lectin family DUF4252 PF14060.1 EDO15318.1 - 0.0053 16.3 0.4 2.5 7.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4252) EVI2A PF05399.6 EDO15318.1 - 0.013 14.8 0.0 0.029 13.6 0.0 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) MSC PF09402.5 EDO15318.1 - 0.08 11.6 0.6 0.12 11.0 0.4 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Pho86 PF11124.3 EDO15319.1 - 1.3e-108 362.5 0.7 1.5e-108 362.3 0.5 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 DUF1687 PF07955.6 EDO15321.1 - 3.1e-33 114.5 1.3 3.5e-33 114.4 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Rep_3 PF01051.16 EDO15321.1 - 0.067 12.7 0.2 0.074 12.6 0.1 1.1 1 0 0 1 1 1 0 Initiator Replication protein CN_hydrolase PF00795.17 EDO15322.1 - 8.6e-24 83.9 0.0 1.2e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-H2C2 PF09337.5 EDO15323.1 - 1.6e-19 69.0 5.1 3.4e-19 67.9 3.5 1.6 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EDO15323.1 - 0.0002 21.3 0.0 0.00053 19.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EDO15323.1 - 0.078 13.1 0.0 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Telomerase_RBD PF12009.3 EDO15324.1 - 0.026 14.4 1.0 0.03 14.2 0.7 1.0 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain Pkinase PF00069.20 EDO15325.1 - 8.1e-57 192.3 0.0 1.2e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15325.1 - 4.9e-38 130.6 0.0 7.2e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO15325.1 - 5.3e-05 22.3 0.0 0.00013 21.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EDO15325.1 - 0.011 14.5 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 EDO15325.1 - 0.062 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase TrkH PF02386.11 EDO15326.1 - 2.5e-135 450.6 8.8 1.1e-134 448.5 0.7 2.4 2 1 0 2 2 2 2 Cation transport protein SR-25 PF10500.4 EDO15326.1 - 0.0016 17.9 16.4 0.0016 17.9 11.4 4.0 4 1 0 4 4 4 1 Nuclear RNA-splicing-associated protein CPSase_L_D2 PF02786.12 EDO15327.1 - 1.8e-115 383.5 1.2 3.1e-84 281.5 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EDO15327.1 - 2e-47 159.9 0.0 5.3e-47 158.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EDO15327.1 - 1.9e-44 151.4 0.0 4.3e-44 150.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EDO15327.1 - 1.5e-42 144.6 0.0 2.9e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 EDO15327.1 - 3.1e-41 139.9 0.1 1.8e-20 73.0 0.0 3.0 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EDO15327.1 - 5.5e-39 132.7 0.1 1.3e-38 131.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 EDO15327.1 - 2.8e-35 121.5 0.2 7.5e-34 116.8 0.1 2.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EDO15327.1 - 4.3e-33 114.6 0.5 1.2e-21 77.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDO15327.1 - 2.1e-24 85.8 0.2 3.8e-14 52.1 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EDO15327.1 - 1.1e-22 79.7 0.0 8.8e-22 76.8 0.0 2.7 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EDO15327.1 - 1.1e-15 57.5 2.2 6.6e-09 35.4 0.2 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EDO15327.1 - 3.2e-15 55.9 0.6 1.7e-07 30.7 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EDO15327.1 - 1.2e-06 28.1 0.0 2.7e-05 23.7 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EDO15327.1 - 1.9e-05 24.5 1.4 0.2 11.4 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 EDO15327.1 - 0.029 13.8 0.0 0.074 12.5 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family TrkA_N PF02254.13 EDO15327.1 - 0.073 13.0 1.2 0.25 11.3 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain mIF3 PF14877.1 EDO15328.1 - 4.5e-64 215.1 7.0 4.5e-64 215.1 4.8 2.2 2 0 0 2 2 2 1 Mitochondrial translation initiation factor IF3_C PF00707.17 EDO15328.1 - 0.0056 16.3 1.7 0.011 15.4 0.4 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain Solute_trans_a PF03619.11 EDO15329.1 - 4.5e-85 285.2 18.2 4.5e-85 285.2 12.6 1.5 2 0 0 2 2 2 1 Organic solute transporter Ostalpha Mito_carr PF00153.22 EDO15330.1 - 5.3e-64 211.9 2.2 4.9e-22 77.4 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein SIR2 PF02146.12 EDO15331.1 - 4e-54 183.0 0.0 6e-54 182.4 0.0 1.3 1 0 0 1 1 1 1 Sir2 family FYVE_2 PF02318.11 EDO15331.1 - 0.66 9.8 3.4 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Peptidase_C48 PF02902.14 EDO15332.1 - 1e-38 133.1 0.3 3.3e-38 131.4 0.2 1.9 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Dimeth_Pyl PF09505.5 EDO15332.1 - 0.078 11.2 0.1 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) AATF-Che1 PF13339.1 EDO15332.1 - 0.52 10.4 7.2 2.3 8.4 2.1 2.7 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Ead_Ea22 PF13935.1 EDO15332.1 - 0.55 10.5 6.9 0.24 11.7 1.9 2.2 1 1 1 2 2 2 0 Ead/Ea22-like protein Ras PF00071.17 EDO15333.1 - 6.5e-64 214.1 0.4 7.8e-64 213.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO15333.1 - 9.3e-20 71.3 0.1 1.6e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO15333.1 - 1.6e-19 69.7 0.3 2.1e-19 69.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDO15333.1 - 4.8e-08 32.4 0.1 5.8e-08 32.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO15333.1 - 6.2e-08 32.3 0.1 6.5e-07 28.9 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EDO15333.1 - 1.1e-07 31.2 0.2 1.4e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDO15333.1 - 6.4e-06 26.1 0.1 1e-05 25.4 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO15333.1 - 7.7e-05 22.0 0.1 0.00091 18.5 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EDO15333.1 - 0.0021 18.0 0.2 0.023 14.7 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO15333.1 - 0.0028 17.8 0.1 0.015 15.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EDO15333.1 - 0.0086 15.2 0.1 0.025 13.7 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EDO15333.1 - 0.013 15.0 0.3 0.056 12.9 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA PF00004.24 EDO15333.1 - 0.033 14.3 0.1 0.17 12.0 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.18 EDO15333.1 - 0.037 12.8 0.0 0.081 11.7 0.0 1.5 1 0 0 1 1 1 0 MCM2/3/5 family G-alpha PF00503.15 EDO15333.1 - 0.046 12.3 0.7 0.43 9.2 0.5 2.4 1 1 0 1 1 1 0 G-protein alpha subunit DUF815 PF05673.8 EDO15333.1 - 0.061 12.2 0.0 0.18 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TFCD_C PF12612.3 EDO15333.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal DUF3437 PF11919.3 EDO15334.1 - 1.1e-29 101.9 0.0 4.6e-29 99.9 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) SMC_N PF02463.14 EDO15335.1 - 5.2e-61 205.6 21.4 9.8e-61 204.7 14.8 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDO15335.1 - 1.7e-25 89.3 0.4 1.8e-24 85.9 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EDO15335.1 - 3.4e-10 40.6 45.6 3.4e-10 40.6 31.6 6.6 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EDO15335.1 - 8.6e-10 39.0 25.5 2.7e-08 34.1 2.3 4.9 2 2 3 5 5 5 2 AAA domain AAA_29 PF13555.1 EDO15335.1 - 5.1e-08 32.3 0.1 1e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EDO15335.1 - 0.00026 19.6 15.3 0.00026 19.6 10.6 5.2 3 2 2 5 5 5 3 AAA domain AAA_15 PF13175.1 EDO15335.1 - 0.00053 19.1 42.3 0.00053 19.1 29.3 4.8 2 2 1 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 EDO15335.1 - 0.0097 16.2 0.2 0.0097 16.2 0.1 6.1 3 3 0 4 4 4 2 ABC transporter Reo_sigmaC PF04582.7 EDO15335.1 - 0.62 9.1 31.1 0.088 11.9 2.0 5.4 5 1 0 6 6 6 0 Reovirus sigma C capsid protein Filament PF00038.16 EDO15335.1 - 1.6 8.1 96.2 0.017 14.6 19.4 5.7 3 2 1 5 5 5 0 Intermediate filament protein WD40 PF00400.27 EDO15336.1 - 2.9e-47 156.9 17.4 1e-10 41.0 0.7 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EDO15336.1 - 1.4e-13 50.2 0.3 3e-13 49.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO15336.1 - 9.4e-08 31.5 0.0 2.4e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 EDO15336.1 - 0.0077 16.1 0.1 0.0077 16.1 0.1 3.7 4 0 0 4 4 4 1 PRANC domain WW PF00397.21 EDO15337.1 - 3.7e-05 23.4 0.6 3.7e-05 23.4 0.4 2.4 3 0 0 3 3 3 1 WW domain PAT1 PF09770.4 EDO15337.1 - 1.1 7.4 40.9 1.2 7.2 28.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DnaJ PF00226.26 EDO15339.1 - 1.8e-24 85.2 3.7 3.9e-24 84.1 2.6 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDO15339.1 - 7.2e-23 80.2 1.9 1.4e-16 60.1 0.3 2.8 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDO15339.1 - 5.4e-12 45.5 17.3 5.4e-12 45.5 12.0 1.9 2 0 0 2 2 2 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 EDO15339.1 - 0.0074 16.6 14.0 0.054 13.8 10.0 2.1 1 1 1 2 2 2 2 Cytochrome c3 HypA PF01155.14 EDO15339.1 - 0.011 15.4 5.7 0.032 13.9 0.6 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrome_C7 PF14522.1 EDO15339.1 - 0.28 10.8 16.9 4.1 7.1 11.9 2.4 1 1 0 1 1 1 0 Cytochrome c7 Cytochrome_CBB3 PF13442.1 EDO15339.1 - 0.34 11.0 12.5 3 8.0 0.0 3.8 3 1 1 4 4 4 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C554 PF13435.1 EDO15339.1 - 1 9.3 13.5 15 5.6 0.1 2.8 1 1 0 2 2 2 0 Cytochrome c554 and c-prime Cytochrom_C PF00034.16 EDO15339.1 - 8.3 7.3 7.8 13 6.6 0.0 3.6 4 0 0 4 4 4 0 Cytochrome c Acetyltransf_1 PF00583.19 EDO15340.1 - 1.1e-14 54.1 0.0 1.7e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO15340.1 - 6.8e-11 42.1 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO15340.1 - 0.00024 20.9 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO15340.1 - 0.0011 19.0 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDO15340.1 - 0.0077 16.1 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain LSM PF01423.17 EDO15341.1 - 1.5e-16 59.6 0.1 1.7e-16 59.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain Pyr_redox_dim PF02852.17 EDO15342.1 - 3.5e-42 142.8 0.0 9.1e-42 141.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EDO15342.1 - 1.3e-40 139.4 12.2 5.1e-38 130.9 8.5 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO15342.1 - 7.6e-22 77.5 4.6 1e-18 67.4 0.2 3.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDO15342.1 - 2.4e-13 49.9 1.7 4.1e-11 42.6 0.1 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO15342.1 - 3.6e-11 42.9 1.1 3.5e-05 23.7 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EDO15342.1 - 8.3e-10 39.0 0.4 4e-06 27.0 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDO15342.1 - 2.3e-09 36.6 6.1 2.2e-08 33.3 2.2 2.6 2 1 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EDO15342.1 - 5.3e-07 28.4 10.6 0.00016 20.3 0.5 4.1 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.19 EDO15342.1 - 6.1e-07 28.6 1.3 6.1e-07 28.6 0.9 3.1 2 1 0 3 3 3 1 FAD binding domain DAO PF01266.19 EDO15342.1 - 3.1e-06 26.3 12.7 0.0059 15.5 1.1 3.8 2 2 2 4 4 4 3 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDO15342.1 - 1.5e-05 24.2 9.2 0.019 14.0 0.3 3.7 2 1 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 EDO15342.1 - 2.9e-05 23.1 1.0 0.067 12.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EDO15342.1 - 0.0003 19.9 5.6 0.0013 17.8 0.5 2.4 1 1 1 2 2 2 1 Thi4 family THF_DHG_CYH_C PF02882.14 EDO15342.1 - 0.00066 18.7 0.5 0.0054 15.8 0.1 2.4 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AlaDh_PNT_C PF01262.16 EDO15342.1 - 0.00075 19.1 0.5 0.17 11.4 0.0 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EDO15342.1 - 0.013 15.1 0.1 0.013 15.1 0.1 3.1 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PTS_IIB PF02302.12 EDO15342.1 - 0.049 14.1 0.4 18 5.9 0.0 3.0 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit Lycopene_cycl PF05834.7 EDO15342.1 - 0.45 9.3 2.8 1.9 7.2 0.3 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EDO15342.1 - 0.49 8.9 2.5 1.2 7.6 0.3 2.1 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EDO15342.1 - 1.4 8.2 7.1 0.12 11.7 0.1 2.6 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fcf2 PF08698.6 EDO15343.1 - 2e-31 107.9 2.6 2e-31 107.9 1.8 2.1 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing PRP1_N PF06424.7 EDO15343.1 - 0.03 14.6 0.2 0.03 14.6 0.2 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF4598 PF15370.1 EDO15343.1 - 0.096 12.9 1.8 4.7 7.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) Seryl_tRNA_N PF02403.17 EDO15343.1 - 0.11 12.4 4.0 2.8 7.9 0.1 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain tRNA-synt_2d PF01409.15 EDO15344.1 - 2.6e-90 301.9 0.0 3.3e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EDO15344.1 - 1.9e-07 30.8 0.2 4.7e-07 29.5 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EDO15344.1 - 6.2e-06 25.2 0.1 0.00014 20.7 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_His PF13393.1 EDO15344.1 - 0.01 14.9 0.0 0.07 12.1 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase DUF465 PF04325.8 EDO15344.1 - 0.024 14.3 0.9 0.024 14.3 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF465) HTH_45 PF14947.1 EDO15344.1 - 0.028 14.2 3.5 0.17 11.6 0.1 2.9 3 0 0 3 3 3 0 Winged helix-turn-helix PaaX PF07848.7 EDO15344.1 - 0.076 13.0 0.0 11 6.1 0.0 3.2 3 0 0 3 3 3 0 PaaX-like protein Rtf2 PF04641.7 EDO15345.1 - 0.12 11.5 12.9 0.32 10.1 8.9 1.6 1 0 0 1 1 1 0 Rtf2 RING-finger NST1 PF13945.1 EDO15345.1 - 4.3 7.3 22.3 0.38 10.8 11.1 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator EPL1 PF10513.4 EDO15346.1 - 1e-36 126.6 1.6 1e-36 126.6 1.1 4.1 3 1 0 3 3 3 1 Enhancer of polycomb-like MscS_TM PF12794.2 EDO15346.1 - 5 5.6 5.3 11 4.5 3.7 1.5 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 STE2 PF02116.10 EDO15347.1 - 1.5e-104 349.0 28.8 1.8e-104 348.7 19.9 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR RabGAP-TBC PF00566.13 EDO15348.1 - 1.4e-21 77.0 3.8 2.9e-21 75.9 2.6 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Gly_transf_sug PF04488.10 EDO15350.1 - 3.5e-23 81.9 1.1 1.4e-22 80.0 0.0 2.5 3 0 0 3 3 3 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EDO15350.1 - 0.025 13.0 3.8 1 7.7 0.5 2.4 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2401 PF10287.4 EDO15351.1 - 2.1e-90 302.3 6.1 3.3e-90 301.6 4.3 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EDO15351.1 - 1.7e-28 98.5 0.6 1.7e-28 98.5 0.4 1.7 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) RAMP4 PF06624.7 EDO15352.1 - 0.074 12.5 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 DUF1366 PF07104.6 EDO15352.1 - 0.075 12.6 0.3 0.075 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Ribosomal_L30_N PF08079.7 EDO15352.1 - 1.6 8.8 6.3 1.8 8.6 4.4 1.1 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain Glyco_transf_15 PF01793.11 EDO15353.1 - 1.3e-131 438.4 12.7 1.7e-131 438.1 8.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NIF PF03031.13 EDO15354.1 - 2.5e-42 144.2 0.4 5.1e-42 143.2 0.1 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Pro_isomerase PF00160.16 EDO15355.1 - 5.8e-06 26.5 0.0 1.5e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD VPS28 PF03997.7 EDO15356.1 - 4.7e-67 225.2 0.5 4.7e-67 225.2 0.4 1.4 2 0 0 2 2 2 1 VPS28 protein Arrestin_C PF02752.17 EDO15357.1 - 0.0034 17.4 2.0 0.0034 17.4 1.4 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MCM PF00493.18 EDO15358.1 - 1.9e-135 450.9 0.0 3.2e-135 450.2 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDO15358.1 - 1.1e-26 93.6 1.2 1.1e-25 90.4 0.1 3.0 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EDO15358.1 - 3.3e-08 32.9 0.1 9.6e-06 24.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDO15358.1 - 3e-07 30.2 0.0 3.5e-06 26.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EDO15358.1 - 0.003 17.9 0.1 0.01 16.2 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDO15358.1 - 0.036 13.6 0.0 0.14 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EDO15358.1 - 0.048 13.8 0.1 0.55 10.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDO15358.1 - 0.061 12.8 0.1 0.56 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DER1 PF04511.10 EDO15359.1 - 3.4e-33 114.8 13.9 3.9e-33 114.6 9.7 1.0 1 0 0 1 1 1 1 Der1-like family TMEM169 PF15052.1 EDO15359.1 - 4.7 7.1 8.7 7.8 6.4 2.1 2.3 1 1 1 2 2 2 0 TMEM169 protein family polyprenyl_synt PF00348.12 EDO15360.1 - 6.9e-45 152.9 0.1 8.8e-45 152.5 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SH3_1 PF00018.23 EDO15361.1 - 9.1e-12 44.1 0.0 2.6e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 SH3 domain PX PF00787.19 EDO15361.1 - 2.5e-11 43.3 0.0 5.4e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_9 PF14604.1 EDO15361.1 - 2e-08 33.6 0.0 7.6e-05 22.2 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain PB1 PF00564.19 EDO15361.1 - 2.6e-07 30.1 0.4 7.9e-07 28.6 0.3 1.8 1 0 0 1 1 1 1 PB1 domain SH3_2 PF07653.12 EDO15361.1 - 5.4e-07 29.0 0.0 0.02 14.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain GH97_C PF14509.1 EDO15361.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation Ribosomal_L30 PF00327.15 EDO15362.1 - 3.6e-14 52.0 0.7 9.6e-14 50.7 0.5 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DNA_pol_viral_C PF00336.13 EDO15362.1 - 0.028 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain RFX_DNA_binding PF02257.10 EDO15363.1 - 9.4e-34 115.4 0.4 3.3e-33 113.6 0.3 2.0 1 0 0 1 1 1 1 RFX DNA-binding domain BAF1_ABF1 PF04684.8 EDO15363.1 - 9.4e-05 21.4 11.7 9.4e-05 21.4 8.1 2.7 3 0 0 3 3 3 2 BAF1 / ABF1 chromatin reorganising factor Radical_SAM_N PF08497.5 EDO15363.1 - 0.014 14.3 3.0 0.03 13.2 2.1 1.5 1 0 0 1 1 1 0 Radical SAM N-terminal DnaJ PF00226.26 EDO15364.1 - 7.5e-24 83.2 0.3 1.2e-23 82.6 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDO15364.1 - 3e-23 81.5 1.2 2.1e-20 72.3 0.1 2.6 2 1 0 2 2 2 2 DnaJ C terminal domain DUF3589 PF12141.3 EDO15365.1 - 5.9e-58 196.3 5.0 2.1e-57 194.5 3.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) PMSR PF01625.16 EDO15366.1 - 7.2e-49 165.6 0.4 9.2e-49 165.3 0.3 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase COX4 PF02936.9 EDO15367.1 - 7.1e-10 38.7 0.0 9.9e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV UPF0197 PF05251.7 EDO15368.1 - 0.004 17.4 5.4 0.0049 17.1 3.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) K1 PF02960.9 EDO15368.1 - 0.051 13.6 1.0 0.058 13.4 0.7 1.2 1 0 0 1 1 1 0 K1 glycoprotein YIF1 PF03878.10 EDO15368.1 - 0.067 12.3 1.2 0.072 12.2 0.9 1.0 1 0 0 1 1 1 0 YIF1 Tetraspannin PF00335.15 EDO15368.1 - 0.41 9.9 5.5 0.42 9.8 3.8 1.0 1 0 0 1 1 1 0 Tetraspanin family DUF751 PF05421.6 EDO15368.1 - 2.1 8.7 6.5 0.38 11.0 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF751) CLTH PF10607.4 EDO15369.1 - 3.3e-17 62.5 7.3 7e-17 61.4 5.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EDO15369.1 - 1.9e-16 60.2 0.2 5.7e-16 58.7 0.1 1.9 1 0 0 1 1 1 1 SPRY domain Daxx PF03344.10 EDO15369.1 - 0.75 8.2 30.9 0.011 14.2 15.8 1.8 2 0 0 2 2 2 0 Daxx Family BUD22 PF09073.5 EDO15369.1 - 5 6.0 28.1 0.14 11.2 14.8 1.8 2 0 0 2 2 2 0 BUD22 SspB PF04386.8 EDO15369.1 - 5.5 6.5 9.7 13 5.3 6.8 1.6 1 0 0 1 1 1 0 Stringent starvation protein B COPI_C PF06957.6 EDO15369.1 - 5.7 5.3 13.2 9.5 4.6 9.2 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus AdoHcyase PF05221.12 EDO15370.1 - 3.1e-139 462.4 0.1 3.6e-139 462.2 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EDO15370.1 - 1.9e-85 284.6 2.7 2.9e-85 284.0 1.8 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EDO15370.1 - 2.6e-08 33.2 0.1 4.9e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EDO15370.1 - 0.0012 18.2 0.3 0.0023 17.3 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EDO15370.1 - 0.0019 18.1 0.1 0.004 17.1 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain HSBP1 PF06825.7 EDO15371.1 - 6.1e-05 22.5 0.2 0.19 11.3 0.0 2.8 2 0 0 2 2 2 2 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.7 EDO15371.1 - 0.0054 16.5 10.6 1.4 8.7 0.1 4.0 4 0 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EDO15371.1 - 0.67 9.8 6.0 5.5 6.9 0.1 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) SAPS PF04499.10 EDO15372.1 - 5.3e-163 543.0 12.6 5.3e-163 543.0 8.7 2.5 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein DnaJ PF00226.26 EDO15373.1 - 1.1e-13 50.6 5.7 8.6e-13 47.8 3.6 2.2 2 0 0 2 2 2 1 DnaJ domain PEN-2 PF10251.4 EDO15374.1 - 0.01 16.0 4.5 0.1 12.8 1.7 2.4 2 1 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Adaptin_binding PF10199.4 EDO15375.1 - 1.2e-08 35.3 7.2 0.00094 19.4 0.1 2.7 2 1 1 3 3 3 2 Alpha and gamma adaptin binding protein p34 DUF1077 PF06417.7 EDO15376.1 - 9e-48 160.7 3.1 1.1e-47 160.4 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) PsbX PF06596.6 EDO15376.1 - 0.15 11.7 0.1 0.15 11.7 0.1 1.7 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) THUMP PF02926.12 EDO15377.1 - 1.9e-23 82.9 1.5 4e-23 81.9 1.1 1.5 1 0 0 1 1 1 1 THUMP domain Sec15 PF04091.7 EDO15378.1 - 9.8e-115 383.1 14.8 2.6e-114 381.7 10.2 1.8 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Peptidase_M20 PF01546.23 EDO15379.1 - 7.2e-30 103.9 0.0 1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDO15379.1 - 3.2e-11 42.9 0.0 5.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF848 PF05852.6 EDO15379.1 - 0.066 13.0 0.1 0.18 11.6 0.0 1.6 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Mito_carr PF00153.22 EDO15380.1 - 2.4e-37 126.5 11.8 2.9e-20 71.7 0.2 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein POP1 PF06978.6 EDO15380.1 - 0.021 14.4 0.7 0.03 13.9 0.5 1.1 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 GARS_A PF01071.14 EDO15381.1 - 3.3e-81 271.5 0.0 5.6e-81 270.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EDO15381.1 - 5.8e-35 119.7 0.4 2.2e-34 117.9 0.0 2.3 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EDO15381.1 - 6e-29 101.0 0.0 1.6e-28 99.6 0.0 1.8 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EDO15381.1 - 6.6e-28 96.7 0.1 1.6e-27 95.5 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EDO15381.1 - 3.2e-16 59.3 2.8 1.6e-15 57.0 0.9 2.7 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EDO15381.1 - 3.5e-11 43.1 0.0 4.2e-10 39.6 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EDO15381.1 - 1.4e-07 30.9 0.0 2.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDO15381.1 - 1.5e-06 27.2 0.0 3.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EDO15381.1 - 0.00011 22.1 0.1 0.0005 19.9 0.0 2.2 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EDO15381.1 - 0.0052 16.1 0.3 0.014 14.6 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Cse1 PF08506.5 EDO15383.1 - 1.4e-163 543.7 4.2 3.1e-163 542.6 2.9 1.6 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EDO15383.1 - 5.7e-107 357.7 9.6 1.3e-106 356.5 6.7 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EDO15383.1 - 7.5e-16 57.8 0.3 4.1e-14 52.2 0.0 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EDO15383.1 - 0.00018 21.4 4.8 0.0097 15.8 0.0 4.1 3 0 0 3 3 3 2 Exportin 1-like protein DUF1955 PF09205.5 EDO15383.1 - 0.037 13.5 0.0 0.13 11.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) APC10 PF03256.11 EDO15384.1 - 5.2e-55 186.0 0.0 7.2e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EDO15384.1 - 0.014 15.2 0.0 0.047 13.5 0.0 1.9 1 0 0 1 1 1 0 F5/8 type C domain Nfu_N PF08712.6 EDO15385.1 - 3.8e-25 87.3 0.0 9.6e-25 86.0 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EDO15385.1 - 1.7e-22 78.9 0.0 3.1e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 EDO15385.1 - 0.012 15.4 1.3 0.012 15.4 0.9 1.9 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Opi1 PF08618.5 EDO15386.1 - 1e-29 103.7 16.5 4.8e-16 58.7 0.1 3.3 2 2 1 3 3 3 3 Transcription factor Opi1 Bystin PF05291.6 EDO15386.1 - 0.011 14.6 0.1 0.029 13.3 0.0 1.7 2 0 0 2 2 2 0 Bystin CLU PF13236.1 EDO15387.1 - 1.4e-76 256.7 0.2 3.3e-76 255.6 0.1 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EDO15387.1 - 4.7e-35 121.0 0.0 1.9e-23 83.2 0.0 3.4 2 0 0 2 2 2 2 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EDO15387.1 - 3.3e-17 62.3 1.7 3.3e-17 62.3 1.2 2.8 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EDO15387.1 - 5.9e-11 42.1 0.3 1.9e-06 27.6 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EDO15387.1 - 0.00011 21.9 0.1 0.033 14.1 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.7 EDO15387.1 - 0.0072 16.1 0.0 0.026 14.3 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.1 EDO15387.1 - 0.045 13.5 2.1 14 5.6 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO15387.1 - 0.059 13.0 0.1 8.7 6.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat BUD22 PF09073.5 EDO15388.1 - 7.2e-108 361.4 48.7 9.4e-108 361.0 33.8 1.1 1 0 0 1 1 1 1 BUD22 SUKH-3 PF14433.1 EDO15388.1 - 0.047 13.4 1.6 0.093 12.5 0.1 2.2 2 0 0 2 2 2 0 SUKH-3 immunity protein Spc42p PF11544.3 EDO15389.1 - 3.5e-33 113.3 12.6 3.5e-33 113.3 8.7 3.9 5 0 0 5 5 5 1 Spindle pole body component Spc42p RepA_C PF04796.7 EDO15389.1 - 0.061 12.9 0.3 9.1 5.8 0.1 2.3 2 0 0 2 2 2 0 Plasmid encoded RepA protein DivIVA PF05103.8 EDO15389.1 - 0.59 10.1 15.7 1.4 8.9 0.1 2.9 2 1 1 3 3 3 0 DivIVA protein FliD_N PF02465.13 EDO15389.1 - 0.88 9.9 12.7 0.13 12.6 1.5 2.9 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus TMF_TATA_bd PF12325.3 EDO15389.1 - 2.7 7.7 16.2 0.026 14.2 1.8 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 EDO15389.1 - 4.8 7.0 7.6 13 5.5 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) KilA-N PF04383.8 EDO15390.1 - 1.7e-05 24.4 1.4 0.00042 19.8 0.0 2.8 2 1 0 2 2 2 1 KilA-N domain Pex14_N PF04695.8 EDO15390.1 - 0.095 12.7 2.9 0.15 12.0 2.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apq12 PF12716.2 EDO15391.1 - 3.3e-08 33.0 11.9 3.3e-08 33.0 8.2 1.9 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis DUF4131 PF13567.1 EDO15391.1 - 0.13 11.6 1.7 0.15 11.4 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1516 PF07457.6 EDO15391.1 - 0.4 10.7 6.2 0.079 13.0 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1516) Metallophos PF00149.23 EDO15392.1 - 3.4e-28 98.4 6.1 4.9e-28 97.9 4.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YcxB PF14317.1 EDO15392.1 - 0.053 12.7 0.1 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 YcxB-like protein bZIP_2 PF07716.10 EDO15393.1 - 4.8e-09 35.9 6.4 1.9e-08 33.9 4.5 2.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDO15393.1 - 2.2e-07 30.7 7.1 2.2e-07 30.7 4.9 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 EDO15393.1 - 0.56 10.5 12.7 0.06 13.6 2.5 3.0 2 1 1 3 3 3 0 bZIP Maf transcription factor Pkinase PF00069.20 EDO15394.1 - 7.5e-53 179.3 5.7 1.7e-51 174.8 4.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15394.1 - 3.2e-18 65.7 0.7 5.9e-13 48.4 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EDO15394.1 - 1.3e-05 25.1 0.0 7.9e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDO15394.1 - 0.015 14.3 0.1 0.034 13.2 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EDO15394.1 - 0.015 14.8 0.2 0.015 14.8 0.1 2.3 3 0 0 3 3 3 0 Choline/ethanolamine kinase F_actin_cap_B PF01115.12 EDO15395.1 - 8.1e-101 336.2 0.5 9.4e-101 336.0 0.3 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit SNF2_N PF00176.18 EDO15396.1 - 1.7e-69 233.9 1.0 3.2e-69 233.0 0.7 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO15396.1 - 3.2e-15 55.7 0.0 2e-14 53.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO15396.1 - 0.00015 21.3 0.0 0.00053 19.5 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2675 PF11247.3 EDO15396.1 - 0.014 15.4 0.1 0.055 13.5 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) AAA_22 PF13401.1 EDO15396.1 - 0.12 12.5 1.1 1.2 9.3 0.0 3.1 4 0 0 4 4 4 0 AAA domain SWIRM PF04433.12 EDO15397.1 - 2.4e-32 110.8 0.1 6.7e-32 109.4 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EDO15397.1 - 1.4e-11 43.7 3.0 2.3e-11 43.0 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EDO15397.1 - 1e-07 31.8 0.1 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO15397.1 - 7.8e-07 29.1 0.5 3.1e-06 27.1 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Peptidase_C48 PF02902.14 EDO15398.1 - 1.7e-29 103.0 0.8 1.7e-29 103.0 0.5 2.6 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Tim44 PF04280.10 EDO15399.1 - 1e-33 116.4 0.0 2.5e-33 115.1 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain ChaB PF06150.7 EDO15399.1 - 0.056 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 ChaB DNA_pol_B_thumb PF14791.1 EDO15400.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta thumb His_biosynth PF00977.16 EDO15401.1 - 4.4e-07 29.3 0.0 5.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein His_biosynth PF00977.16 EDO15402.1 - 0.007 15.6 0.0 0.0075 15.5 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein HLH PF00010.21 EDO15404.1 - 1.4e-13 50.3 1.0 3.5e-13 49.0 0.7 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UCR_hinge PF02320.11 EDO15405.1 - 2e-21 75.7 2.4 3e-21 75.1 1.7 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF506 PF04720.7 EDO15405.1 - 0.018 14.6 5.2 0.02 14.5 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Nop14 PF04147.7 EDO15405.1 - 0.25 9.2 16.1 0.24 9.2 11.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EDO15405.1 - 0.3 9.7 16.4 0.34 9.6 11.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EDO15405.1 - 0.45 10.1 18.8 0.58 9.7 13.1 1.3 1 1 0 1 1 1 0 Sigma-70, non-essential region DUF4211 PF13926.1 EDO15405.1 - 0.74 9.2 5.3 0.71 9.2 3.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4211) AAA_18 PF13238.1 EDO15405.1 - 0.9 9.8 4.9 1.7 8.9 3.4 1.5 1 1 0 1 1 1 0 AAA domain zf-C4H2 PF10146.4 EDO15405.1 - 0.97 9.4 5.5 1.2 9.1 3.8 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein RRN3 PF05327.6 EDO15405.1 - 1.2 7.1 7.7 1.3 7.0 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.7 EDO15405.1 - 1.4 8.1 13.7 1.5 8.0 9.5 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EDO15405.1 - 1.6 6.6 10.5 1.6 6.6 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.1 EDO15405.1 - 1.7 8.3 7.9 2.1 8.0 5.5 1.3 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.8 EDO15405.1 - 2.4 5.8 20.3 2.3 5.8 14.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.7 EDO15405.1 - 2.6 7.2 10.5 3.1 6.9 7.3 1.2 1 0 0 1 1 1 0 NOA36 protein Ycf1 PF05758.7 EDO15405.1 - 2.7 5.6 5.5 2.7 5.6 3.8 1.0 1 0 0 1 1 1 0 Ycf1 IFT57 PF10498.4 EDO15405.1 - 2.8 6.5 10.5 3.2 6.4 7.3 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Na_trans_assoc PF06512.8 EDO15405.1 - 3.9 7.3 13.9 4.4 7.1 9.6 1.0 1 0 0 1 1 1 0 Sodium ion transport-associated Daxx PF03344.10 EDO15405.1 - 4 5.7 18.9 4.4 5.6 13.1 1.0 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 EDO15405.1 - 6.4 6.0 12.8 7.7 5.8 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Dicty_REP PF05086.7 EDO15405.1 - 6.8 4.3 11.2 8.9 3.9 7.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Paf1 PF03985.8 EDO15405.1 - 6.8 5.3 15.1 8.2 5.0 10.5 1.1 1 0 0 1 1 1 0 Paf1 CobT PF06213.7 EDO15405.1 - 8.5 5.4 18.1 9.9 5.2 12.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ribosomal_L29e PF01779.12 EDO15406.1 - 2.1e-24 85.1 8.8 3e-24 84.5 6.1 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family RRM_6 PF14259.1 EDO15407.1 - 8.4e-19 67.3 0.0 1.5e-11 44.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO15407.1 - 4.4e-17 61.4 0.0 1.9e-09 36.9 0.0 3.1 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO15407.1 - 5e-07 29.4 0.0 1.2e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L2_C PF03947.13 EDO15408.1 - 2.5e-41 140.5 2.5 4.1e-41 139.8 1.7 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EDO15408.1 - 2e-13 50.1 0.1 4.7e-13 48.8 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SMC_N PF02463.14 EDO15409.1 - 9.8e-69 230.9 20.3 9e-39 132.9 6.6 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDO15409.1 - 5.1e-21 74.8 0.4 1.5e-20 73.3 0.1 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EDO15409.1 - 3.8e-17 63.2 0.8 3.8e-17 63.2 0.6 6.5 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 EDO15409.1 - 5.7e-08 33.0 46.4 3.1e-06 27.3 0.2 4.9 3 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EDO15409.1 - 2.7e-05 23.5 0.0 6.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EDO15409.1 - 0.55 10.5 0.0 0.55 10.5 0.0 6.6 4 2 2 6 6 6 0 ABC transporter BAG PF02179.11 EDO15410.1 - 5.4e-17 61.6 3.1 9.2e-17 60.9 2.1 1.4 1 0 0 1 1 1 1 BAG domain Salp15 PF12115.3 EDO15410.1 - 0.0082 16.3 0.1 0.011 15.9 0.1 1.2 1 0 0 1 1 1 1 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF2611 PF11022.3 EDO15410.1 - 0.022 14.8 0.4 0.044 13.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) CPSF73-100_C PF11718.3 EDO15410.1 - 0.06 12.7 0.2 0.069 12.4 0.1 1.2 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Asp PF00026.18 EDO15411.1 - 2.2e-48 165.1 2.8 2.7e-48 164.8 1.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO15411.1 - 1.4e-10 41.3 0.1 8.3e-10 38.8 0.0 2.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDO15411.1 - 3.3e-05 24.3 0.5 2.8 8.4 0.0 3.4 3 0 0 3 3 3 3 Aspartyl protease Peptidase_C54 PF03416.14 EDO15412.1 - 1.2e-88 296.8 0.0 1.5e-88 296.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 G-patch PF01585.18 EDO15413.1 - 3.2e-11 42.8 0.5 7.1e-11 41.7 0.3 1.6 1 0 0 1 1 1 1 G-patch domain CRAL_TRIO PF00650.15 EDO15414.1 - 4.4e-39 133.5 0.0 6.7e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDO15414.1 - 3.4e-14 52.7 0.6 9.5e-14 51.2 0.4 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain EXOSC1 PF10447.4 EDO15415.1 - 5e-31 106.4 0.3 1.1e-30 105.3 0.0 1.8 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EDO15415.1 - 0.058 12.6 0.2 11 5.3 0.0 3.1 3 1 0 3 3 3 0 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EDO15415.1 - 0.071 13.2 0.1 4.1 7.5 0.0 2.8 2 0 0 2 2 2 0 S1 RNA binding domain dTMP_synthase PF02593.9 EDO15416.1 - 0.017 14.4 0.4 0.037 13.3 0.3 1.5 1 0 0 1 1 1 0 Thymidylate synthase Med16 PF11635.3 EDO15417.1 - 6.9e-221 735.2 6.5 8.3e-221 734.9 4.5 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Ytp1 PF10355.4 EDO15418.1 - 3.4e-78 262.5 14.8 3.4e-78 262.5 10.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) Peptidase_S8 PF00082.17 EDO15419.1 - 9e-56 189.0 0.5 1.1e-55 188.7 0.3 1.1 1 0 0 1 1 1 1 Subtilase family Peptidase_C1_2 PF03051.10 EDO15420.1 - 1.6e-165 550.9 3.1 1.8e-165 550.7 2.2 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EDO15420.1 - 6.6e-06 26.1 0.1 0.078 12.8 0.2 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Sod_Fe_C PF02777.13 EDO15420.1 - 0.055 13.3 0.1 2.4 8.0 0.0 3.1 3 1 0 3 3 3 0 Iron/manganese superoxide dismutases, C-terminal domain DMRL_synthase PF00885.14 EDO15420.1 - 0.08 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase Fe_hyd_lg_C PF02906.9 EDO15421.1 - 2.8e-74 249.9 0.0 4.1e-74 249.4 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Psb28 PF03912.9 EDO15421.1 - 0.0083 16.0 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 Psb28 protein G6PD_C PF02781.11 EDO15422.1 - 1.4e-130 434.4 0.0 1.9e-130 434.0 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EDO15422.1 - 9.1e-65 218.3 0.0 1.4e-64 217.6 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Mannosyl_trans3 PF11051.3 EDO15423.1 - 3.2e-70 236.5 1.2 3.2e-70 236.5 0.8 1.8 2 0 0 2 2 2 1 Mannosyltransferase putative DUF3953 PF13129.1 EDO15426.1 - 3.2 7.4 5.0 1.1 8.8 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3953) Pkinase PF00069.20 EDO15427.1 - 4.2e-51 173.5 0.4 8.8e-45 152.8 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15427.1 - 2.1e-18 66.3 0.0 5.2e-18 65.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDO15427.1 - 0.035 13.1 0.0 0.1 11.6 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDO15427.1 - 0.063 12.2 0.0 0.26 10.2 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Ribonucleas_3_3 PF14622.1 EDO15428.1 - 2.1e-17 63.3 0.0 3.6e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EDO15428.1 - 0.059 13.8 0.1 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 Ribonuclease III domain GIT_SHD PF08518.6 EDO15429.1 - 6.3e-22 76.6 1.1 9.1e-12 44.1 0.2 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF972 PF06156.8 EDO15429.1 - 3.1 8.1 18.0 0.07 13.4 1.2 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF972) Septin PF00735.13 EDO15430.1 - 2.1e-109 364.9 9.4 2.1e-109 364.9 6.5 3.0 2 1 0 2 2 2 1 Septin Dynamin_N PF00350.18 EDO15430.1 - 4.6e-07 29.8 1.9 4.6e-07 29.8 1.3 3.1 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EDO15430.1 - 2.9e-05 23.9 0.2 0.00013 21.8 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDO15430.1 - 0.0031 16.7 4.4 0.029 13.5 3.1 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDO15430.1 - 0.048 13.8 0.2 0.5 10.4 0.0 2.7 2 1 1 3 3 3 0 AAA domain DUF2937 PF11157.3 EDO15430.1 - 0.38 10.0 2.3 0.68 9.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) V_ATPase_I PF01496.14 EDO15430.1 - 7.3 4.3 12.7 14 3.3 8.8 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_M20 PF01546.23 EDO15431.1 - 1.2e-23 83.5 0.0 2.2e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EDO15431.1 - 2.6e-14 52.4 4.6 0.00066 19.4 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat M20_dimer PF07687.9 EDO15431.1 - 2.1e-11 43.5 0.0 3.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.3 EDO15431.1 - 0.03 12.4 0.0 1.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 MRP-L27 PF09809.4 EDO15432.1 - 2e-28 98.2 1.4 3.2e-28 97.6 1.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SecY PF00344.15 EDO15433.1 - 6e-20 71.4 1.1 6.7e-20 71.2 0.8 1.1 1 0 0 1 1 1 1 SecY translocase TrbC PF04956.8 EDO15433.1 - 0.031 14.2 2.4 0.35 10.8 0.4 2.4 2 0 0 2 2 2 0 TrbC/VIRB2 family SecY PF00344.15 EDO15434.1 - 7.2e-24 84.3 6.5 9e-24 84.0 4.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EDO15434.1 - 2.7e-10 39.5 2.2 1.3e-09 37.3 0.0 2.7 2 0 0 2 2 2 1 Plug domain of Sec61p A_deaminase PF00962.17 EDO15435.1 - 4.1e-17 62.1 0.0 8.1e-11 41.4 0.0 3.7 2 2 1 3 3 3 3 Adenosine/AMP deaminase DUF619 PF04768.8 EDO15436.1 - 2.2e-54 183.3 0.0 5.2e-54 182.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Baculo_PEP_C PF04513.7 EDO15436.1 - 0.002 17.9 1.3 0.002 17.9 0.9 2.1 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Sld5 PF05916.6 EDO15437.1 - 1.2e-15 57.6 2.0 2.4e-15 56.7 1.4 1.5 1 0 0 1 1 1 1 GINS complex protein Peptidase_M28 PF04389.12 EDO15438.1 - 8e-32 110.4 0.0 1.4e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EDO15438.1 - 4.5e-09 35.9 0.0 1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EDO15438.1 - 0.0012 18.3 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EDO15438.1 - 0.0054 15.5 0.0 0.0086 14.8 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase BLVR PF06375.6 EDO15438.1 - 0.013 15.3 0.4 0.028 14.2 0.3 1.5 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DnaJ PF00226.26 EDO15439.1 - 2.6e-20 71.8 4.4 2.6e-20 71.8 3.0 2.6 2 0 0 2 2 2 1 DnaJ domain MBOAT PF03062.14 EDO15440.1 - 6.8e-66 222.5 40.9 1e-65 221.9 28.4 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EDO15440.1 - 0.00042 20.3 4.2 0.0013 18.7 2.9 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Peptidase_M76 PF09768.4 EDO15441.1 - 1.1e-74 249.5 0.6 1.5e-74 249.2 0.4 1.1 1 0 0 1 1 1 1 Peptidase M76 family DUF1347 PF07079.6 EDO15441.1 - 0.022 12.9 0.2 0.033 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1347) Tox-MPTase2 PF15638.1 EDO15441.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 SprT-like PF10263.4 EDO15441.1 - 0.12 12.0 0.6 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 SprT-like family PH_9 PF15410.1 EDO15442.1 - 0.00099 19.2 0.1 0.0037 17.4 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain MAS20 PF02064.10 EDO15442.1 - 0.11 12.4 0.2 0.27 11.1 0.1 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor Pga1 PF10333.4 EDO15443.1 - 6.5e-79 263.7 9.9 7.4e-79 263.5 6.9 1.0 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator VacA PF02691.10 EDO15443.1 - 0.013 13.1 0.1 0.014 13.0 0.0 1.1 1 0 0 1 1 1 0 Vacuolating cyotoxin zf-AN1 PF01428.11 EDO15444.1 - 1.1e-11 44.3 14.4 1.8e-11 43.6 10.0 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Phage_GP20 PF06810.6 EDO15444.1 - 0.00059 19.3 6.9 0.0012 18.2 4.8 1.5 1 0 0 1 1 1 1 Phage minor structural protein GP20 Ndc80_HEC PF03801.8 EDO15444.1 - 0.054 12.9 1.3 0.23 10.8 1.2 1.8 2 0 0 2 2 2 0 HEC/Ndc80p family UPF1_Zn_bind PF09416.5 EDO15444.1 - 9.8 5.7 10.5 3.6 7.1 4.0 2.1 2 0 0 2 2 2 0 RNA helicase (UPF2 interacting domain) Pkinase PF00069.20 EDO15445.1 - 2.2e-32 112.2 0.1 4.6e-32 111.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15445.1 - 3.6e-12 45.9 0.0 9.5e-12 44.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 EDO15445.1 - 0.0023 17.0 0.0 0.0051 15.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO15445.1 - 0.0031 17.2 0.1 0.066 12.9 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF4557 PF15101.1 EDO15445.1 - 1.1 9.0 9.2 4.7 7.0 6.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) Strep_SA_rep PF06696.6 EDO15446.1 - 0.12 12.2 0.4 0.17 11.6 0.3 1.3 1 0 0 1 1 1 0 Streptococcal surface antigen repeat Ribosomal_L17 PF01196.14 EDO15447.1 - 2e-23 82.8 0.1 5.2e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L17 CBFD_NFYB_HMF PF00808.18 EDO15448.1 - 7.7e-05 22.6 0.2 0.00019 21.4 0.2 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2151 PF10221.4 EDO15448.1 - 0.0094 14.1 13.1 0.012 13.7 9.1 1.1 1 0 0 1 1 1 1 Cell cycle and development regulator Ribosomal_60s PF00428.14 EDO15448.1 - 0.02 15.2 5.6 0.02 15.2 3.9 2.0 1 1 0 1 1 1 0 60s Acidic ribosomal protein SprA-related PF12118.3 EDO15448.1 - 0.031 13.6 9.8 0.042 13.1 6.8 1.3 1 0 0 1 1 1 0 SprA-related family PSD4 PF07631.6 EDO15448.1 - 0.032 14.5 0.1 0.075 13.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1592) Histone PF00125.19 EDO15448.1 - 0.037 14.1 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CobT PF06213.7 EDO15448.1 - 0.077 12.1 18.9 0.099 11.7 13.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Hid1 PF12722.2 EDO15448.1 - 0.67 7.5 11.2 0.91 7.1 7.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1510 PF07423.6 EDO15448.1 - 4.1 6.7 21.6 9.3 5.5 15.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Astro_capsid PF03115.9 EDO15448.1 - 5.8 5.0 11.1 7.6 4.6 7.7 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RCC1_2 PF13540.1 EDO15450.1 - 5.8e-13 48.0 10.4 2.7e-05 23.6 0.7 4.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EDO15450.1 - 1.9e-09 37.5 1.8 0.016 15.3 0.2 5.4 5 1 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat Rad60-SLD PF11976.3 EDO15451.1 - 4.1e-22 77.6 5.1 7.6e-22 76.7 2.4 2.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Arrestin_C PF02752.17 EDO15452.1 - 5.8e-18 65.3 3.6 1.2e-15 57.8 0.1 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EDO15452.1 - 1.2e-07 31.6 2.4 4.9e-05 23.1 0.1 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Exo70 PF03081.10 EDO15453.1 - 1.3e-96 323.6 1.0 1.3e-96 323.6 0.7 2.3 2 0 0 2 2 2 2 Exo70 exocyst complex subunit RNA_lig_T4_1 PF09511.5 EDO15454.1 - 1e-78 263.8 0.1 1.8e-78 263.0 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 EDO15454.1 - 9.4e-74 247.8 1.6 1.3e-73 247.3 1.1 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 EDO15454.1 - 3.1e-71 238.6 1.7 5.7e-71 237.7 0.2 2.2 2 0 0 2 2 2 1 tRNA ligase kinase domain LigT_PEase PF02834.11 EDO15454.1 - 0.11 12.4 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 LigT like Phosphoesterase NTR2 PF15458.1 EDO15455.1 - 5e-45 153.7 20.9 5e-45 153.7 14.5 1.6 1 1 1 2 2 2 1 Nineteen complex-related protein 2 YbaB_DNA_bd PF02575.11 EDO15455.1 - 0.025 14.4 0.1 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family GWT1 PF06423.7 EDO15456.1 - 1.8e-50 170.5 6.3 7e-50 168.6 4.4 2.1 1 0 0 1 1 1 1 GWT1 Ion_trans_2 PF07885.11 EDO15457.1 - 7.4e-28 96.0 27.1 6.1e-17 61.1 9.0 3.9 4 0 0 4 4 4 2 Ion channel Na_H_Exchanger PF00999.16 EDO15458.1 - 4.8e-62 209.6 29.8 6.9e-62 209.1 20.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TraG_N PF07916.6 EDO15458.1 - 0.077 11.4 0.0 0.077 11.4 0.0 1.6 2 0 0 2 2 2 0 TraG-like protein, N-terminal region Pkinase PF00069.20 EDO15459.1 - 1.8e-65 220.6 0.0 4.2e-65 219.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15459.1 - 6.8e-44 149.8 0.0 1.3e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO15459.1 - 4.7e-10 38.9 0.0 2.4e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EDO15459.1 - 0.34 10.5 0.0 0.65 9.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L21p PF00829.16 EDO15460.1 - 8.3e-06 25.8 0.2 1.2e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein ChAPs PF09295.5 EDO15461.1 - 2.3e-41 141.8 7.1 6e-29 101.0 2.7 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EDO15461.1 - 2e-05 24.1 0.0 4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 TPR repeat DUF3439 PF11921.3 EDO15461.1 - 0.01 15.6 0.3 0.021 14.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) TPR_17 PF13431.1 EDO15461.1 - 0.012 15.7 0.0 0.049 13.8 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDO15461.1 - 0.017 14.8 0.2 7.9 6.5 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDO15461.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO15461.1 - 0.074 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat GCS PF03074.11 EDO15462.1 - 1.9e-140 468.1 1.1 2.6e-140 467.7 0.7 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase GTP_EFTU PF00009.22 EDO15463.1 - 2.7e-58 196.5 0.0 1.1e-57 194.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EDO15463.1 - 5.7e-26 90.1 0.0 1.3e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EDO15463.1 - 1.2e-19 69.9 0.0 1.1e-09 37.9 0.0 2.8 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDO15463.1 - 3e-08 33.6 1.7 5.9e-08 32.7 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO15463.1 - 0.0009 19.1 0.1 0.0026 17.6 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EDO15463.1 - 0.01 15.0 0.0 0.029 13.6 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Zn_clus PF00172.13 EDO15464.1 - 1.1e-06 28.4 14.1 2.1e-06 27.5 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EDO15464.1 - 1.9e-05 24.4 0.0 4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EDO15464.1 - 0.1 13.0 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain zf-C2HC5 PF06221.8 EDO15465.1 - 3.4e-22 77.9 5.4 5.9e-22 77.1 3.7 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.1 EDO15465.1 - 3.2 7.0 6.9 1.4 8.1 3.1 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zf-CCCH PF00642.19 EDO15466.1 - 0.00056 19.5 1.3 0.00056 19.5 0.9 5.3 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pam16 PF03656.8 EDO15467.1 - 2.7e-49 166.1 0.9 3.3e-49 165.8 0.6 1.1 1 0 0 1 1 1 1 Pam16 NTP_transferase PF00483.18 EDO15467.1 - 0.024 13.9 0.1 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase PHD PF00628.24 EDO15468.1 - 5.1e-10 38.8 6.8 1.2e-09 37.6 4.7 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EDO15468.1 - 9.7e-07 29.2 4.1 1.3e-06 28.8 0.0 2.9 2 1 0 2 2 2 1 SET domain PHD_2 PF13831.1 EDO15468.1 - 0.0025 17.0 1.6 0.0053 16.0 1.1 1.5 1 0 0 1 1 1 1 PHD-finger Pkinase PF00069.20 EDO15469.1 - 1.2e-54 185.1 0.3 1.8e-52 178.1 0.1 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15469.1 - 6.5e-27 94.2 0.1 2e-25 89.3 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Acyltransferase PF01553.16 EDO15470.1 - 7.4e-33 112.7 0.0 1.1e-32 112.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TMEM164 PF14808.1 EDO15470.1 - 0.063 12.4 0.5 0.087 11.9 0.3 1.1 1 0 0 1 1 1 0 TMEM164 family La PF05383.12 EDO15471.1 - 1.7e-23 82.1 0.0 3.8e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EDO15471.1 - 7.5e-05 22.2 0.6 0.00043 19.8 0.3 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO15471.1 - 0.00037 20.4 0.3 0.0016 18.3 0.1 2.1 1 1 1 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Lipocalin_7 PF14651.1 EDO15471.1 - 0.011 15.3 1.3 0.15 11.8 0.3 2.4 2 1 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family BRAP2 PF07576.7 EDO15471.1 - 0.041 13.4 0.1 0.087 12.4 0.1 1.6 1 0 0 1 1 1 0 BRCA1-associated protein 2 Hema_esterase PF03996.10 EDO15471.1 - 0.051 12.7 0.5 0.56 9.3 0.0 2.0 1 1 0 2 2 2 0 Hemagglutinin esterase Mgr1 PF08602.5 EDO15471.1 - 0.68 8.8 5.1 0.28 10.1 1.0 1.8 1 1 1 2 2 2 0 Mgr1-like, i-AAA protease complex subunit zf-H2C2_2 PF13465.1 EDO15472.1 - 1.1e-05 25.4 2.6 1.1e-05 25.4 1.8 5.6 4 2 1 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO15472.1 - 9.7e-05 22.4 25.5 0.0033 17.6 0.7 4.9 5 0 0 5 5 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO15472.1 - 0.00016 21.7 2.5 0.00016 21.7 1.7 4.8 5 0 0 5 5 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDO15472.1 - 0.0014 18.7 8.9 0.15 12.2 0.3 3.8 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EDO15472.1 - 0.0049 16.7 13.0 1.1 9.2 0.0 4.4 3 1 0 3 3 3 2 C2H2-type zinc finger DUF4606 PF15379.1 EDO15472.1 - 0.012 15.7 4.0 0.014 15.4 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4606) zf-RING_3 PF14369.1 EDO15472.1 - 0.029 14.3 2.3 0.19 11.7 0.2 2.7 3 0 0 3 3 3 0 zinc-finger DUF3354 PF11834.3 EDO15472.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3354) DZR PF12773.2 EDO15472.1 - 0.43 10.4 8.3 0.14 11.9 1.2 2.5 2 1 0 2 2 2 0 Double zinc ribbon Cript PF10235.4 EDO15472.1 - 0.72 10.2 4.3 0.98 9.8 0.4 2.6 3 0 0 3 3 2 0 Microtubule-associated protein CRIPT Zn-ribbon_8 PF09723.5 EDO15472.1 - 2.1 8.3 12.0 11 6.1 0.1 3.5 2 1 1 3 3 3 0 Zinc ribbon domain C1_1 PF00130.17 EDO15472.1 - 7.5 6.3 10.3 1.9 8.2 0.3 3.1 3 1 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) ELO PF01151.13 EDO15473.1 - 2e-59 200.9 25.6 2.5e-59 200.5 17.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family CNH PF00780.17 EDO15474.1 - 1.2e-77 260.9 0.5 3e-77 259.7 0.3 1.7 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EDO15474.1 - 6.4e-37 126.5 0.1 6.4e-37 126.5 0.1 3.4 2 1 1 3 3 3 1 Pleckstrin homology domain RhoGEF PF00621.15 EDO15474.1 - 4.4e-32 111.4 0.0 4.4e-32 111.4 0.0 2.8 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.16 EDO15474.1 - 5.6e-13 48.4 0.0 1.4e-12 47.1 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TFIIA PF03153.8 EDO15474.1 - 5 6.9 32.3 9.1 6.0 22.4 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit P21-Arc PF04062.9 EDO15475.1 - 2.2e-79 265.2 0.1 2.5e-79 265.1 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit HSP70 PF00012.15 EDO15476.1 - 3.5e-216 718.8 14.3 4e-216 718.5 9.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO15476.1 - 7.4e-18 64.2 3.4 9.1e-16 57.3 0.5 2.5 2 0 0 2 2 2 2 MreB/Mbl protein PilM_2 PF11104.3 EDO15476.1 - 0.00042 19.3 1.1 0.3 9.9 0.5 3.1 2 1 1 3 3 3 2 Type IV pilus assembly protein PilM; FtsA PF14450.1 EDO15476.1 - 0.017 14.9 7.8 4.4 7.1 1.6 4.2 3 1 0 3 3 3 0 Cell division protein FtsA BcrAD_BadFG PF01869.15 EDO15476.1 - 0.018 14.3 0.0 1.9 7.6 0.0 2.7 1 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.11 EDO15476.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DUF45 PF01863.12 EDO15476.1 - 0.67 9.7 8.0 0.66 9.7 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 F-box PF00646.28 EDO15477.1 - 0.00056 19.5 4.7 0.0016 18.0 3.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EDO15477.1 - 0.0034 17.0 4.6 0.0057 16.3 1.3 2.6 2 0 0 2 2 2 1 F-box-like Arrestin_C PF02752.17 EDO15478.1 - 3.4e-15 56.3 0.2 3.4e-15 56.3 0.1 3.0 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EDO15478.1 - 5.4e-09 36.0 0.0 5.3e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain zf-C2H2 PF00096.21 EDO15479.1 - 1.1e-08 34.8 15.3 7e-05 22.9 0.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO15479.1 - 7e-07 29.2 10.9 5.4e-06 26.4 0.9 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO15479.1 - 2.3e-06 27.5 11.9 0.0028 17.8 0.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDO15479.1 - 0.008 16.0 3.1 0.43 10.5 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EDO15479.1 - 1 9.1 3.5 24 4.7 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EDO15479.1 - 2.1 8.6 12.5 3.9 7.7 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ribosomal_S8 PF00410.14 EDO15480.1 - 2.2e-26 92.2 0.1 3e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Spt4 PF06093.8 EDO15481.1 - 3.1e-29 100.6 0.4 3.6e-29 100.4 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger 60KD_IMP PF02096.15 EDO15482.1 - 3.9e-20 72.3 7.7 5.1e-20 71.9 5.3 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein DUF3321 PF11968.3 EDO15482.1 - 0.013 15.1 0.3 0.02 14.5 0.2 1.2 1 0 0 1 1 1 0 Putative methyltransferase (DUF3321) FA_hydroxylase PF04116.8 EDO15483.1 - 3.3e-16 59.6 18.6 3.3e-16 59.6 12.9 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Metallophos PF00149.23 EDO15484.1 - 2.7e-11 43.2 0.1 5.1e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDO15484.1 - 1.4e-05 24.9 0.0 2.9e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AICARFT_IMPCHas PF01808.13 EDO15484.1 - 0.048 12.7 0.0 0.077 12.0 0.0 1.2 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme Bromodomain PF00439.20 EDO15485.1 - 8.9e-26 89.6 6.8 5e-14 51.9 0.7 3.0 2 1 0 2 2 2 2 Bromodomain BAH PF01426.13 EDO15485.1 - 1.4e-20 73.1 1.6 4.8e-20 71.4 0.1 2.5 2 1 0 2 2 2 1 BAH domain Transaldolase PF00923.14 EDO15486.1 - 2.3e-94 315.7 0.1 2.7e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 Transaldolase DUF2439 PF10382.4 EDO15487.1 - 1.9e-26 92.0 3.8 1.9e-26 92.0 2.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) DUF2273 PF10031.4 EDO15488.1 - 0.23 11.1 2.7 0.45 10.1 1.8 1.5 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Fungal_trans PF04082.13 EDO15489.1 - 1.9e-12 46.6 3.3 4e-12 45.5 2.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO15489.1 - 3.7e-08 33.1 9.0 8e-08 32.0 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tom22 PF04281.8 EDO15489.1 - 0.011 15.2 0.6 0.77 9.2 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Ferric_reduct PF01794.14 EDO15490.1 - 9e-19 67.7 4.6 9e-19 67.7 3.2 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EDO15490.1 - 1e-13 51.5 0.0 1.6e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDO15490.1 - 1.2e-06 28.3 0.2 4e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 EDO15490.1 - 0.021 15.3 0.0 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Ran-binding PF05508.6 EDO15492.1 - 1.9e-112 375.1 9.0 3.2e-112 374.3 6.2 1.3 1 0 0 1 1 1 1 RanGTP-binding protein CHASE3 PF05227.8 EDO15492.1 - 0.018 14.7 1.6 0.033 13.8 1.1 1.4 1 0 0 1 1 1 0 CHASE3 domain CENP-Q PF13094.1 EDO15492.1 - 2.1 8.3 9.9 0.095 12.7 2.4 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Copper-fist PF00649.13 EDO15493.1 - 1.4e-21 75.3 0.5 1.4e-21 75.3 0.3 2.4 1 1 1 2 2 2 1 Copper fist DNA binding domain Menin PF05053.8 EDO15493.1 - 0.1 10.7 6.8 0.13 10.3 4.7 1.1 1 0 0 1 1 1 0 Menin DUF3461 PF11944.3 EDO15494.1 - 0.066 13.0 8.8 0.062 13.1 0.8 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3461) ICL PF00463.16 EDO15495.1 - 1.1e-161 538.6 0.1 1.2e-161 538.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EDO15495.1 - 1.1e-08 34.6 0.0 1.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Astro_capsid PF03115.9 EDO15496.1 - 1.5 7.0 8.8 1.9 6.6 6.1 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor RRN3 PF05327.6 EDO15496.1 - 2.1 6.3 13.5 3.6 5.5 9.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.7 EDO15496.1 - 2.2 7.3 24.3 3.4 6.7 16.9 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TEX19 PF15553.1 EDO15496.1 - 5.6 6.8 13.8 1.8 8.4 6.4 2.3 2 0 0 2 2 2 0 Testis-expressed protein 19 AAA_17 PF13207.1 EDO15497.1 - 1.4e-09 38.7 0.0 1.3e-08 35.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDO15497.1 - 1.9e-07 31.0 0.0 0.00096 19.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EDO15497.1 - 8.7e-07 29.3 0.0 3.6e-06 27.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDO15497.1 - 0.00015 21.4 0.0 0.00051 19.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO15497.1 - 0.00024 21.1 0.0 0.00072 19.5 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 EDO15497.1 - 0.00075 19.6 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EDO15497.1 - 0.00075 19.6 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDO15497.1 - 0.00097 19.3 0.0 0.0023 18.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EDO15497.1 - 0.0012 19.2 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter PRK PF00485.13 EDO15497.1 - 0.0018 17.8 0.0 0.3 10.6 0.0 2.6 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 EDO15497.1 - 0.0028 16.7 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EDO15497.1 - 0.0041 17.0 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDO15497.1 - 0.0043 17.0 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EDO15497.1 - 0.0083 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain Mg_chelatase PF01078.16 EDO15497.1 - 0.0096 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KTI12 PF08433.5 EDO15497.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.1 EDO15497.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 EDO15497.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 EDO15497.1 - 0.023 13.9 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ADK PF00406.17 EDO15497.1 - 0.024 14.4 0.0 0.61 9.9 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase APS_kinase PF01583.15 EDO15497.1 - 0.025 14.2 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase cobW PF02492.14 EDO15497.1 - 0.033 13.6 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EDO15497.1 - 0.034 13.6 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.9 EDO15497.1 - 0.034 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 6PF2K PF01591.13 EDO15497.1 - 0.037 13.1 0.0 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Arch_ATPase PF01637.13 EDO15497.1 - 0.046 13.4 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Guanylate_kin PF00625.16 EDO15497.1 - 0.048 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase AAA_29 PF13555.1 EDO15497.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EDO15497.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EDO15497.1 - 0.083 11.7 0.0 0.19 10.5 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 EDO15497.1 - 0.086 12.2 0.0 0.25 10.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 EDO15497.1 - 0.089 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EDO15497.1 - 0.12 12.7 0.3 0.19 12.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EDO15497.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase NACHT PF05729.7 EDO15497.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ETF PF01012.16 EDO15498.1 - 1.5e-34 119.0 0.0 3.3e-34 117.9 0.0 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EDO15498.1 - 3.2e-34 116.3 0.1 5.8e-34 115.5 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Sulfate_transp PF00916.15 EDO15499.1 - 6e-57 192.7 11.3 6e-57 192.7 7.9 2.1 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EDO15499.1 - 1.2e-27 95.4 4.2 1.2e-27 95.4 2.9 2.1 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EDO15499.1 - 5.4e-19 67.7 0.4 2e-18 65.8 0.0 2.1 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 EDO15499.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 1 0 1 1 1 0 STAS domain DUF1072 PF06380.6 EDO15499.1 - 0.12 12.0 9.0 0.029 14.0 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) BAF1_ABF1 PF04684.8 EDO15500.1 - 9.9e-116 387.4 58.1 1.8e-64 218.4 1.0 4.6 2 1 3 5 5 5 4 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.10 EDO15500.1 - 0.0013 18.2 0.4 0.0025 17.3 0.3 1.4 1 0 0 1 1 1 1 MuDR family transposase OAD_gamma PF04277.8 EDO15500.1 - 0.0073 16.6 2.1 0.03 14.6 1.5 2.2 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain mRNA_stabil PF13929.1 EDO15501.1 - 1.2e-106 355.9 18.0 2.3e-106 355.0 12.5 1.4 1 0 0 1 1 1 1 mRNA stabilisation Oligomerisation PF02410.10 EDO15501.1 - 2.2e-17 62.9 2.7 9e-17 60.9 0.1 3.0 3 1 1 4 4 4 1 Oligomerisation domain TFIIE-A_C-term PF11521.3 EDO15501.1 - 0.0048 16.8 0.5 0.43 10.5 0.0 2.5 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha KTI12 PF08433.5 EDO15502.1 - 7.5e-97 323.7 1.7 8.5e-97 323.5 1.2 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EDO15502.1 - 1.9e-06 28.2 0.7 8e-06 26.1 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDO15502.1 - 1.8e-05 24.6 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EDO15502.1 - 0.00031 20.4 0.0 0.00085 19.0 0.0 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 EDO15502.1 - 0.0007 20.3 0.0 0.0017 19.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO15502.1 - 0.036 14.2 0.3 0.27 11.3 0.0 2.5 2 2 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EDO15502.1 - 0.041 13.7 0.3 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EDO15502.1 - 0.05 13.5 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EDO15502.1 - 0.075 13.2 0.0 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EDO15502.1 - 0.087 13.0 0.2 0.28 11.3 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EDO15502.1 - 0.13 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 EDO15503.1 - 6.3e-13 48.6 0.8 2.3e-12 46.8 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDO15503.1 - 2.4e-05 23.5 0.8 5.2e-05 22.4 0.5 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EDO15503.1 - 0.00042 19.8 3.3 0.0022 17.4 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EDO15503.1 - 0.0012 19.3 1.5 0.15 12.5 0.1 2.9 3 0 0 3 3 3 1 Miro-like protein Septin PF00735.13 EDO15503.1 - 0.0025 16.8 0.8 0.0041 16.1 0.0 1.7 2 0 0 2 2 2 1 Septin FeoB_N PF02421.13 EDO15503.1 - 0.0071 15.6 0.2 0.023 14.0 0.2 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EDO15503.1 - 0.014 14.2 0.3 1.9 7.1 0.0 2.3 1 1 1 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EDO15503.1 - 0.015 15.1 0.7 2.3 8.0 0.0 2.9 1 1 1 2 2 2 0 Dynamin family AAA_29 PF13555.1 EDO15503.1 - 0.015 14.7 0.0 0.048 13.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EDO15503.1 - 0.039 13.3 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EDO15503.1 - 0.069 13.9 0.2 0.2 12.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO15503.1 - 0.092 13.0 2.0 0.18 12.1 0.2 2.3 2 0 0 2 2 2 0 AAA domain SOR_SNZ PF01680.12 EDO15504.1 - 9.6e-105 348.7 5.4 1.2e-104 348.3 3.7 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EDO15504.1 - 1.1e-09 37.7 1.5 2.1e-07 30.3 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EDO15504.1 - 0.0012 18.2 0.1 0.018 14.3 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein Dus PF01207.12 EDO15504.1 - 0.0012 17.7 0.2 0.41 9.4 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) TMP-TENI PF02581.12 EDO15504.1 - 0.0023 17.0 0.3 0.17 10.9 0.0 2.8 3 0 0 3 3 3 1 Thiamine monophosphate synthase/TENI Med10 PF09748.4 EDO15504.1 - 0.005 16.6 0.1 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 Transcription factor subunit Med10 of Mediator complex IGPS PF00218.16 EDO15504.1 - 0.011 14.8 0.1 0.14 11.1 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase NanE PF04131.9 EDO15504.1 - 0.02 13.8 0.7 0.27 10.2 0.0 2.4 1 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 EDO15504.1 - 0.036 13.2 0.3 0.036 13.2 0.2 2.4 2 2 0 2 2 2 0 Nitronate monooxygenase PEP_mutase PF13714.1 EDO15504.1 - 0.056 12.6 1.0 1.5 7.9 0.1 2.8 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase 1-cysPrx_C PF10417.4 EDO15504.1 - 0.067 12.8 0.1 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of 1-Cys peroxiredoxin SNO PF01174.14 EDO15505.1 - 6.6e-73 244.3 0.0 2.5e-38 131.6 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EDO15505.1 - 1e-06 28.4 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.19 EDO15505.1 - 0.00098 18.6 0.0 0.0031 16.9 0.0 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family DUF4066 PF13278.1 EDO15505.1 - 0.018 14.3 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative amidotransferase Peptidase_S51 PF03575.12 EDO15505.1 - 0.14 11.8 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 Xylo_C PF12529.3 EDO15506.1 - 0.069 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Xylosyltransferase C terminal Drc1-Sld2 PF11719.3 EDO15507.1 - 3.1e-70 237.4 25.0 1.2e-69 235.4 17.3 1.9 1 1 0 1 1 1 1 DNA replication and checkpoint protein Spt5_N PF11942.3 EDO15507.1 - 7.1 7.3 13.5 6.8 7.3 1.0 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal UTP15_C PF09384.5 EDO15508.1 - 2.9e-50 169.8 0.1 4.7e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EDO15508.1 - 2.2e-18 65.3 3.6 8.8e-05 22.2 0.0 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF2410 PF10307.4 EDO15508.1 - 0.22 10.8 2.4 0.83 8.9 1.1 2.2 1 1 1 2 2 2 0 Hypothetical protein (DUF2410) WD40 PF00400.27 EDO15509.1 - 2.8e-28 96.7 34.2 2.1e-05 24.1 0.2 11.2 11 2 1 12 12 12 8 WD domain, G-beta repeat eIF2A PF08662.6 EDO15509.1 - 1.7e-06 27.8 2.8 0.066 12.9 0.1 4.9 4 2 2 6 6 6 4 Eukaryotic translation initiation factor eIF2A NAD_binding_10 PF13460.1 EDO15510.1 - 1.6e-25 90.1 0.0 1.9e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EDO15510.1 - 3.9e-07 29.5 0.0 6.9e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 EDO15510.1 - 3.3e-05 23.8 0.0 6.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EDO15510.1 - 4.8e-05 23.6 0.0 7.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EDO15510.1 - 0.00021 20.0 0.1 0.00031 19.5 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ldh_1_N PF00056.18 EDO15510.1 - 0.00023 21.0 0.1 0.00031 20.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EDO15510.1 - 0.0087 16.5 0.1 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EDO15510.1 - 0.019 15.4 0.2 0.029 14.7 0.2 1.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EDO15510.1 - 0.028 13.8 0.1 0.058 12.8 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peptidase_M41 PF01434.13 EDO15511.1 - 2e-76 256.1 0.1 4.6e-76 255.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EDO15511.1 - 8.7e-43 145.6 0.0 2.9e-42 143.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EDO15511.1 - 4e-07 30.1 0.3 5.4e-06 26.5 0.2 2.7 1 1 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 EDO15511.1 - 9.6e-05 23.1 5.5 0.00057 20.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EDO15511.1 - 0.00089 18.9 0.2 0.0078 15.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDO15511.1 - 0.0011 19.0 0.1 0.17 12.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDO15511.1 - 0.0014 17.6 0.0 0.0035 16.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EDO15511.1 - 0.0027 16.4 0.0 0.0056 15.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EDO15511.1 - 0.0045 16.6 0.4 0.012 15.2 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EDO15511.1 - 0.01 15.2 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EDO15511.1 - 0.029 14.3 0.6 0.13 12.2 0.1 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EDO15511.1 - 0.035 13.5 1.2 0.21 10.9 0.3 2.4 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 EDO15511.1 - 0.035 13.9 0.0 0.13 12.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain DUF384 PF04064.8 EDO15511.1 - 0.066 12.7 1.5 0.16 11.5 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF384) AAA_18 PF13238.1 EDO15511.1 - 0.4 10.9 0.0 0.4 10.9 0.0 4.5 3 2 1 4 4 2 0 AAA domain MFS_1 PF07690.11 EDO15512.1 - 1.9e-40 138.6 23.3 6.6e-40 136.9 16.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO15512.1 - 1.6e-14 53.4 11.6 1.6e-14 53.4 8.0 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter Arf PF00025.16 EDO15513.1 - 2.7e-57 192.8 0.1 3e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDO15513.1 - 7.7e-07 28.6 0.0 9.2e-07 28.3 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EDO15513.1 - 2.7e-06 26.3 0.0 4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 EDO15513.1 - 1.1e-05 24.6 0.0 1.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO15513.1 - 0.00017 21.0 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EDO15513.1 - 0.00047 20.6 0.0 0.00063 20.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EDO15513.1 - 0.00064 18.9 0.0 0.00071 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ArgK PF03308.11 EDO15513.1 - 0.012 14.4 0.4 0.13 10.9 0.3 2.0 1 1 0 1 1 1 0 ArgK protein 2-Hacid_dh_C PF02826.14 EDO15514.1 - 9.4e-38 129.1 0.0 1.5e-37 128.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EDO15514.1 - 7.3e-05 22.6 0.0 0.00033 20.5 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EDO15514.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh PF00389.25 EDO15514.1 - 0.064 12.7 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 EDO15514.1 - 0.1 13.0 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Kinetocho_Slk19 PF12709.2 EDO15515.1 - 8.7e-32 109.0 16.0 8.7e-32 109.0 11.1 8.1 2 2 7 9 9 9 3 Central kinetochore-associated Filament PF00038.16 EDO15515.1 - 0.11 11.9 97.6 0.038 13.4 32.2 3.5 1 1 2 3 3 3 0 Intermediate filament protein RhoGAP PF00620.22 EDO15516.1 - 7.5e-37 126.2 0.1 7.5e-37 126.2 0.1 2.3 3 0 0 3 3 3 1 RhoGAP domain PH PF00169.24 EDO15516.1 - 2.1e-09 37.4 0.1 5.8e-09 36.0 0.1 1.8 1 0 0 1 1 1 1 PH domain PX PF00787.19 EDO15516.1 - 7.4e-05 22.5 0.0 0.0002 21.1 0.0 1.8 1 0 0 1 1 1 1 PX domain Microtub_assoc PF07989.6 EDO15516.1 - 0.003 17.3 2.0 0.0065 16.2 0.5 2.3 2 0 0 2 2 2 1 Microtubule associated Radical_SAM PF04055.16 EDO15517.1 - 3.2e-16 59.9 0.0 4.4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Hist_deacetyl PF00850.14 EDO15518.1 - 3.3e-63 213.8 0.1 6.1e-63 212.9 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain DFF40 PF09230.5 EDO15518.1 - 0.0062 15.9 0.1 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 DNA fragmentation factor 40 kDa Peptidase_C14 PF00656.17 EDO15519.1 - 2e-68 230.7 0.1 4.2e-68 229.7 0.0 1.5 1 0 0 1 1 1 1 Caspase domain Terminase_4 PF05119.7 EDO15520.1 - 0.2 11.8 5.9 3.2 7.9 0.9 2.9 2 0 0 2 2 2 0 Phage terminase, small subunit NUDIX PF00293.23 EDO15521.1 - 9.5e-28 96.5 0.0 1.4e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain IGPD PF00475.13 EDO15522.1 - 7.2e-61 204.3 0.3 1.2e-60 203.5 0.2 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase APG6 PF04111.7 EDO15523.1 - 2.8e-109 365.0 12.8 2.8e-109 365.0 8.9 1.4 2 0 0 2 2 2 1 Autophagy protein Apg6 Exonuc_VII_L PF02601.10 EDO15523.1 - 4.5 6.3 14.0 8.9 5.3 0.1 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit MMR_HSR1 PF01926.18 EDO15524.1 - 5.4e-09 36.0 0.0 1.6e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDO15524.1 - 0.00091 18.4 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EDO15524.1 - 0.0012 18.1 0.5 0.013 14.7 0.1 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B RNA_helicase PF00910.17 EDO15524.1 - 0.033 14.3 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.22 EDO15524.1 - 0.038 13.4 0.1 7.5 5.9 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Noc2 PF03715.8 EDO15525.1 - 4.3e-101 337.7 2.1 1.1e-100 336.3 1.5 1.7 1 0 0 1 1 1 1 Noc2p family Mei5 PF10376.4 EDO15526.1 - 2e-36 125.6 13.9 2.3e-36 125.4 9.6 1.0 1 0 0 1 1 1 1 Double-strand recombination repair protein CagA PF03507.8 EDO15526.1 - 0.001 19.0 0.3 0.001 19.0 0.2 1.9 1 1 1 2 2 2 1 CagA exotoxin DUF3837 PF12939.2 EDO15526.1 - 0.026 14.5 0.7 0.026 14.5 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3837) Syntaxin-6_N PF09177.6 EDO15526.1 - 0.035 14.4 2.0 0.035 14.4 1.4 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal CASP_C PF08172.7 EDO15526.1 - 0.15 11.0 6.4 0.22 10.4 4.4 1.2 1 0 0 1 1 1 0 CASP C terminal Peptidase_M15_2 PF05951.8 EDO15526.1 - 0.25 10.7 2.3 0.6 9.5 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF882) ApoLp-III PF07464.6 EDO15526.1 - 0.65 9.9 13.3 13 5.7 9.2 2.2 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Mitofilin PF09731.4 EDO15526.1 - 1.1 7.8 21.0 2.4 6.6 12.5 1.9 1 1 1 2 2 2 0 Mitochondrial inner membrane protein Lge1 PF11488.3 EDO15526.1 - 9.7 6.4 8.0 2 8.6 0.2 2.6 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 RNA_pol_Rpb2_6 PF00562.23 EDO15527.1 - 4.5e-119 397.6 1.1 4.9e-119 397.5 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDO15527.1 - 3.6e-61 205.6 1.0 5.8e-61 204.9 0.7 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EDO15527.1 - 1.4e-42 145.2 2.7 3.6e-42 143.9 1.9 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EDO15527.1 - 2.1e-30 104.8 0.1 6.1e-30 103.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EDO15527.1 - 2.7e-25 87.9 0.3 2.7e-25 87.9 0.2 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EDO15527.1 - 4.8e-19 67.8 0.5 1.8e-18 66.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EDO15527.1 - 1.8e-11 43.8 0.3 5.6e-11 42.2 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 EDO15527.1 - 0.0026 16.1 0.1 0.0054 15.1 0.1 1.4 1 0 0 1 1 1 1 Baculovirus Y142 protein Tfb2 PF03849.9 EDO15528.1 - 1.2e-158 527.5 1.2 1.8e-158 526.9 0.8 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EDO15528.1 - 5.7e-07 29.3 0.0 2.2e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_6 PF14259.1 EDO15529.1 - 6e-10 38.9 0.1 1.8e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO15529.1 - 1.8e-07 30.7 0.0 4.6e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO15529.1 - 4.2e-06 26.5 0.0 8.2e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LMBR1 PF04791.11 EDO15529.1 - 0.023 13.2 1.1 0.034 12.7 0.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Tim54 PF11711.3 EDO15529.1 - 0.21 10.1 8.0 0.37 9.3 5.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MRI PF15325.1 EDO15529.1 - 1.4 9.9 6.5 61 4.6 3.5 2.5 2 0 0 2 2 2 0 Modulator of retrovirus infection BAF1_ABF1 PF04684.8 EDO15529.1 - 1.6 7.4 26.4 3.3 6.4 18.3 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 EDO15529.1 - 2.7 6.9 6.7 4.8 6.1 4.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Suf PF05843.9 EDO15529.1 - 4.6 6.8 18.7 0.15 11.7 7.7 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) HPIH PF13323.1 EDO15529.1 - 5 6.7 17.1 0.12 12.1 6.6 2.1 2 1 1 3 3 3 0 N-terminal domain with HPIH motif Myb_DNA-bind_6 PF13921.1 EDO15530.1 - 1.9e-12 47.1 2.1 2.7e-10 40.1 0.5 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDO15530.1 - 3.3e-09 36.6 0.9 1.1e-06 28.6 0.1 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain DUF3439 PF11921.3 EDO15530.1 - 0.22 11.2 5.7 1 9.1 4.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TatD_DNase PF01026.16 EDO15531.1 - 5.1e-35 120.9 0.0 7.9e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase PP2C PF00481.16 EDO15532.1 - 1.2e-77 260.7 0.1 1.8e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PTH2 PF01981.11 EDO15533.1 - 5.6e-45 151.7 0.1 7.5e-45 151.3 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 FAM176 PF14851.1 EDO15533.1 - 0.00089 18.9 0.1 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 FAM176 family DUF2457 PF10446.4 EDO15533.1 - 0.0072 15.1 5.6 0.0099 14.6 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) DUF4366 PF14283.1 EDO15533.1 - 0.0086 15.5 0.5 0.013 14.9 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) YL1 PF05764.8 EDO15533.1 - 0.015 14.9 5.4 0.02 14.5 3.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein RXT2_N PF08595.6 EDO15533.1 - 0.079 12.7 1.9 0.12 12.2 1.3 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Sporozoite_P67 PF05642.6 EDO15533.1 - 0.08 10.8 4.7 0.11 10.3 3.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.5 EDO15533.1 - 0.4 10.9 7.8 0.64 10.2 5.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EDO15533.1 - 4 7.8 8.2 6.9 7.0 5.7 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA-ATPase_like PF09820.4 EDO15534.1 - 0.044 12.9 0.0 0.061 12.4 0.0 1.4 2 0 0 2 2 2 0 Predicted AAA-ATPase Cmc1 PF08583.5 EDO15535.1 - 3.5e-18 65.1 6.7 3.5e-18 65.1 4.7 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 EDO15535.1 - 0.0031 16.9 1.1 0.0051 16.1 0.8 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CBM_14 PF01607.19 EDO15535.1 - 0.019 14.9 0.8 0.026 14.4 0.5 1.3 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain DUF3294 PF07957.6 EDO15535.1 - 0.024 14.1 1.9 0.029 13.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) MRP-L28 PF09812.4 EDO15535.1 - 0.056 13.2 2.1 0.078 12.8 1.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 RE_AlwI PF09491.5 EDO15535.1 - 0.057 11.9 3.6 0.059 11.8 2.5 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease CHCH PF06747.8 EDO15535.1 - 0.12 12.3 2.7 2.7 8.0 1.8 2.3 1 1 1 2 2 2 0 CHCH domain Sel1 PF08238.7 EDO15536.1 - 9.9e-42 140.4 8.3 7.8e-06 26.3 0.2 7.6 7 0 0 7 7 7 7 Sel1 repeat Actin PF00022.14 EDO15537.1 - 1.5e-114 382.5 0.0 1.7e-114 382.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EDO15537.1 - 0.022 13.3 0.0 0.17 10.4 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein DUF3449 PF11931.3 EDO15538.1 - 5.4e-67 225.1 0.9 5.4e-67 225.1 0.7 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 EDO15538.1 - 1.6e-07 31.2 12.6 2.7e-07 30.5 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO15538.1 - 1.5e-06 28.1 8.5 4.1e-05 23.6 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDO15538.1 - 0.0015 18.6 3.9 0.06 13.4 0.1 2.8 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 EDO15538.1 - 0.011 15.2 1.0 0.011 15.2 0.7 2.1 2 0 0 2 2 2 0 U1 zinc finger zf-C2H2_4 PF13894.1 EDO15538.1 - 0.24 11.8 5.8 0.46 10.9 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2175 PF09943.4 EDO15538.1 - 3.8 7.6 12.5 0.76 9.8 1.3 3.7 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) tRNA_Me_trans PF03054.11 EDO15539.1 - 3.4e-115 384.4 0.0 3.9e-115 384.2 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 EDO15539.1 - 0.0012 17.8 0.1 0.027 13.3 0.0 2.7 3 0 0 3 3 3 1 NAD synthase Asn_synthase PF00733.16 EDO15539.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Exo_endo_phos PF03372.18 EDO15540.1 - 7.1e-13 49.0 0.0 9.1e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SIR2 PF02146.12 EDO15541.1 - 1.4e-62 210.5 0.0 2.7e-62 209.6 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EDO15541.1 - 1.7e-55 186.8 4.7 1.7e-55 186.8 3.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EDO15541.1 - 0.01 15.5 0.3 5.2 6.8 0.0 2.6 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain DUF2457 PF10446.4 EDO15541.1 - 0.018 13.8 5.8 0.034 12.8 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LETM1 PF07766.8 EDO15542.1 - 0.076 12.0 0.7 0.14 11.2 0.5 1.4 1 0 0 1 1 1 0 LETM1-like protein PAPS_reduct PF01507.14 EDO15543.1 - 6.4e-30 104.2 0.0 1.6e-29 102.9 0.0 1.7 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family DAGK_cat PF00781.19 EDO15544.1 - 3.4e-24 84.7 0.0 7.1e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Ras PF00071.17 EDO15545.1 - 1.1e-57 193.8 0.6 1.4e-57 193.6 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO15545.1 - 1e-21 77.5 0.8 2.3e-21 76.5 0.1 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDO15545.1 - 2.8e-16 59.2 0.4 4.2e-16 58.6 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDO15545.1 - 6.3e-06 26.1 0.0 1.1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EDO15545.1 - 1.1e-05 24.7 0.4 3.6e-05 23.0 0.1 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EDO15545.1 - 1.9e-05 24.2 0.1 0.00012 21.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDO15545.1 - 2.3e-05 23.6 0.2 2.9e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 EDO15545.1 - 0.0014 18.3 0.6 0.0069 16.1 0.4 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EDO15545.1 - 0.0016 18.5 0.0 0.013 15.6 0.0 2.1 1 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EDO15545.1 - 0.0035 16.8 0.6 0.037 13.5 0.4 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EDO15545.1 - 0.011 14.8 0.0 0.028 13.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EDO15545.1 - 0.015 14.8 0.1 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Tenui_NCP PF04876.7 EDO15545.1 - 0.028 13.9 0.1 0.05 13.1 0.1 1.4 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein CAP59_mtransfer PF11735.3 EDO15545.1 - 0.04 13.1 0.6 1.1 8.4 0.0 2.0 1 1 0 2 2 2 0 Cryptococcal mannosyltransferase 1 AAA_16 PF13191.1 EDO15545.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EDO15545.1 - 0.092 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.1 EDO15545.1 - 0.67 10.2 8.0 1.2 9.4 5.5 1.4 1 1 0 1 1 1 0 AAA domain Ribosomal_S28e PF01200.13 EDO15547.1 - 1.4e-33 114.4 3.4 1.5e-33 114.3 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e XLF PF09302.6 EDO15548.1 - 1.1e-05 25.2 1.7 1.2e-05 25.1 0.4 1.6 2 0 0 2 2 2 1 XLF (XRCC4-like factor) DUF3447 PF11929.3 EDO15548.1 - 0.15 11.8 3.8 0.52 10.1 2.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3447) Zn_clus PF00172.13 EDO15549.1 - 1.5e-08 34.4 6.5 4.2e-08 32.9 4.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adenine_glyco PF03352.8 EDO15549.1 - 0.0072 15.8 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 Methyladenine glycosylase ACR_tran PF00873.14 EDO15549.1 - 0.28 8.5 0.0 0.43 7.9 0.0 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Longin PF13774.1 EDO15550.1 - 1.6e-23 82.0 0.7 2.5e-23 81.4 0.5 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EDO15550.1 - 1.7e-17 62.7 0.3 2.7e-17 62.1 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 EDO15550.1 - 0.002 17.9 0.1 0.004 16.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Phi-29_GP16_7 PF06720.6 EDO15550.1 - 0.0092 15.6 0.5 0.015 14.9 0.4 1.3 1 0 0 1 1 1 1 Bacteriophage phi-29 early protein GP16.7 DcpS PF05652.7 EDO15551.1 - 5.6e-41 139.3 0.3 1e-40 138.5 0.2 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 EDO15551.1 - 1.2e-29 102.8 0.1 3.5e-29 101.3 0.1 1.8 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Med4 PF10018.4 EDO15552.1 - 5.4e-42 143.3 4.2 5.4e-42 143.3 2.9 1.8 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF3281 PF11685.3 EDO15552.1 - 0.0065 15.6 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3281) MBOAT PF03062.14 EDO15553.1 - 2.7e-61 207.4 7.6 2.7e-61 207.4 5.3 1.9 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Cnd1 PF12717.2 EDO15554.1 - 1.3e-53 181.4 12.2 6.6e-51 172.6 0.1 5.1 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EDO15554.1 - 3.8e-51 173.0 0.2 1.2e-50 171.5 0.1 1.9 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.17 EDO15554.1 - 9e-12 44.0 2.9 0.056 13.5 0.0 6.2 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.1 EDO15554.1 - 9.9e-12 44.9 0.0 0.0053 17.0 0.0 4.3 3 1 2 5 5 5 4 HEAT repeats HEAT_EZ PF13513.1 EDO15554.1 - 3.2e-06 27.4 0.1 0.69 10.4 0.0 4.9 4 0 0 4 4 4 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EDO15554.1 - 0.057 13.3 0.3 26 4.8 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion AA_permease_2 PF13520.1 EDO15555.1 - 6.9e-87 291.7 46.4 8.4e-87 291.4 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO15555.1 - 6.1e-19 67.7 42.4 8.6e-19 67.2 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease Bromodomain PF00439.20 EDO15556.1 - 2.3e-25 88.3 6.7 1e-12 47.7 0.7 2.8 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EDO15556.1 - 7.1e-20 70.9 0.3 5.6e-19 68.0 0.0 2.4 2 0 0 2 2 2 1 BAH domain Lyase_1 PF00206.15 EDO15557.1 - 2.3e-23 82.8 0.0 3.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EDO15557.1 - 1.6e-15 56.8 0.0 5.3e-15 55.1 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus AsiA PF09010.5 EDO15557.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Anti-Sigma Factor A DUF1331 PF07048.6 EDO15557.1 - 0.053 12.9 0.6 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) Folliculin PF11704.3 EDO15558.1 - 8.8e-53 178.3 0.4 9.9e-53 178.1 0.2 1.0 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Pkinase PF00069.20 EDO15559.1 - 1.7e-68 230.5 0.1 5.2e-68 229.0 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15559.1 - 1.3e-47 162.0 0.2 1.7e-46 158.3 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EDO15559.1 - 3.6e-34 116.8 0.1 9.3e-34 115.5 0.0 1.8 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EDO15559.1 - 1.4e-08 34.7 0.0 4.8e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EDO15559.1 - 3.3e-08 33.2 1.8 4.7e-08 32.7 0.0 2.2 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EDO15559.1 - 5.2e-06 25.6 0.0 5.4e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like DUF2254 PF10011.4 EDO15559.1 - 0.25 9.7 0.1 7.5 4.9 0.0 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) EF-hand_7 PF13499.1 EDO15560.1 - 2.2e-08 34.1 2.3 9.9e-05 22.3 0.1 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDO15560.1 - 2.1e-06 27.1 0.6 0.0047 16.7 0.0 4.2 3 1 1 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 EDO15560.1 - 7.1e-06 24.9 0.2 0.24 10.7 0.0 4.4 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EDO15560.1 - 0.00024 20.6 0.2 0.065 12.8 0.0 3.4 3 1 1 4 4 4 1 EF-hand domain pair Caldesmon PF02029.10 EDO15560.1 - 0.038 12.4 2.5 0.056 11.8 1.7 1.2 1 0 0 1 1 1 0 Caldesmon Septin PF00735.13 EDO15561.1 - 1.9e-95 319.1 0.7 3.4e-95 318.2 0.5 1.4 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EDO15561.1 - 2.6e-05 23.7 0.5 0.00035 20.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EDO15561.1 - 0.00013 21.1 0.1 0.00049 19.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDO15561.1 - 0.00021 21.1 6.3 0.85 9.4 0.1 3.6 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.18 EDO15561.1 - 0.00059 19.7 0.1 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EDO15561.1 - 0.023 14.1 0.2 0.16 11.4 0.1 2.3 2 1 1 3 3 3 0 FtsK/SpoIIIE family AIG1 PF04548.11 EDO15561.1 - 0.029 13.4 0.2 0.029 13.4 0.1 2.4 2 1 0 2 2 2 0 AIG1 family Miro PF08477.8 EDO15561.1 - 0.044 14.2 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein PIN_4 PF13638.1 EDO15562.1 - 0.00028 21.0 0.0 0.00062 19.8 0.0 1.6 1 1 0 1 1 1 1 PIN domain Abhydrolase_1 PF00561.15 EDO15563.1 - 5.1e-21 75.2 0.0 7.4e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO15563.1 - 7.7e-19 67.8 0.0 4.9e-18 65.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO15563.1 - 1.8e-18 67.2 0.0 2.3e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDO15563.1 - 8.2e-13 48.0 0.0 1.6e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EDO15563.1 - 0.0012 18.1 0.0 0.62 9.3 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Glyco_hydro_97 PF10566.4 EDO15563.1 - 0.087 11.9 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Glycoside hydrolase 97 PGAP1 PF07819.8 EDO15563.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF572 PF04502.8 EDO15564.1 - 1.2e-50 172.5 12.3 1.6e-50 172.1 8.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) Tox-ODYAM1 PF15642.1 EDO15564.1 - 0.013 14.1 6.3 0.0048 15.6 2.7 1.5 1 1 0 1 1 1 0 Toxin in Odyssella and Amoebophilus DDE_Tnp_IS1 PF03400.8 EDO15564.1 - 0.015 15.3 0.2 0.056 13.5 0.0 2.0 2 1 0 2 2 2 0 IS1 transposase Mu-like_Com PF10122.4 EDO15564.1 - 0.016 14.2 0.9 0.05 12.6 0.0 2.1 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-FPG_IleRS PF06827.9 EDO15564.1 - 0.13 11.9 1.1 1.1 8.9 0.1 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS IF2_N PF04760.10 EDO15564.1 - 0.49 10.0 4.7 7.5 6.2 0.2 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Trypan_PARP PF05887.6 EDO15565.1 - 0.016 15.0 0.5 0.016 15.0 0.3 1.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SieB PF14163.1 EDO15566.1 - 0.048 13.2 0.3 1.9 8.0 0.1 2.5 1 1 1 2 2 2 0 Superinfection exclusion protein B Peptidase_A22B PF04258.8 EDO15567.1 - 1.4e-68 231.5 12.0 8.2e-68 229.0 8.3 1.9 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EDO15567.1 - 0.00049 19.3 6.2 0.00049 19.3 4.3 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) bZIP_1 PF00170.16 EDO15568.1 - 1e-13 50.9 7.8 2.1e-13 49.9 5.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDO15568.1 - 5.4e-12 45.3 8.1 9e-12 44.6 5.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper KIAA1328 PF15369.1 EDO15568.1 - 3.4e-05 23.8 0.2 5e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised protein KIAA1328 bZIP_Maf PF03131.12 EDO15568.1 - 0.012 15.8 5.6 0.028 14.6 3.9 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor TSC22 PF01166.13 EDO15568.1 - 0.11 12.5 4.8 0.35 10.8 1.5 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.10 EDO15568.1 - 0.19 11.2 2.0 0.54 9.7 1.4 1.8 1 0 0 1 1 1 0 Septum formation initiator H-kinase_dim PF02895.9 EDO15568.1 - 0.42 10.9 6.2 3 8.2 1.5 2.8 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Laminin_II PF06009.7 EDO15568.1 - 4.6 6.9 9.0 0.94 9.2 1.8 2.7 2 1 0 2 2 2 0 Laminin Domain II Urm1 PF09138.6 EDO15569.1 - 3.3e-34 116.8 1.0 3.7e-34 116.7 0.7 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EDO15569.1 - 0.00019 21.7 0.1 0.00023 21.5 0.1 1.2 1 0 0 1 1 1 1 ThiS family YchF-GTPase_C PF06071.8 EDO15569.1 - 0.11 12.2 0.1 0.29 10.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF933) UEV PF05743.8 EDO15570.1 - 1.5e-28 98.9 0.1 3.1e-28 97.8 0.1 1.6 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EDO15570.1 - 1.4e-23 82.2 0.5 3.4e-23 81.0 0.2 1.8 2 0 0 2 2 2 1 Vps23 core domain FlaC_arch PF05377.6 EDO15570.1 - 0.0062 16.3 1.5 0.022 14.6 1.1 1.9 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) ALS_ss_C PF10369.4 EDO15571.1 - 5.8e-20 70.7 0.0 5e-19 67.7 0.0 2.5 2 1 1 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 EDO15571.1 - 7.9e-12 44.3 0.1 1.7e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EDO15571.1 - 6.6e-09 35.4 0.0 1.1e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 ACT domain Limkain-b1 PF11608.3 EDO15571.1 - 0.015 14.9 0.0 0.081 12.6 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 ACT_4 PF13291.1 EDO15571.1 - 0.048 14.0 0.0 0.47 10.8 0.0 2.3 2 0 0 2 2 2 0 ACT domain Ribosomal_L27 PF01016.14 EDO15572.1 - 5.7e-32 109.3 0.5 1e-31 108.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein RRM_1 PF00076.17 EDO15573.1 - 2e-59 197.1 0.1 6.7e-20 70.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO15573.1 - 1.8e-36 123.9 0.0 1.3e-11 44.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO15573.1 - 2.9e-18 65.4 0.0 2.7e-07 30.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PB1 PF00564.19 EDO15573.1 - 0.015 14.9 0.0 7.2 6.3 0.0 2.7 2 0 0 2 2 2 0 PB1 domain WD40 PF00400.27 EDO15574.1 - 3.7e-50 166.0 16.4 4.1e-11 42.3 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EDO15574.1 - 4.6e-11 41.5 10.3 0.0091 14.1 0.0 5.0 1 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDO15574.1 - 6.4e-07 28.4 1.7 0.088 11.5 0.0 3.9 1 1 2 3 3 3 2 Nup133 N terminal like DUF3312 PF11768.3 EDO15574.1 - 4.2e-05 21.9 0.0 0.0001 20.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 EDO15574.1 - 0.0002 19.7 0.0 0.091 11.0 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 EDO15574.1 - 0.0013 17.9 0.3 1.1 8.2 0.1 3.0 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 EDO15574.1 - 0.0038 16.1 0.0 0.023 13.5 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region Hira PF07569.6 EDO15574.1 - 0.005 16.0 0.2 3.4 6.8 0.0 3.7 2 1 2 5 5 5 1 TUP1-like enhancer of split PQQ_2 PF13360.1 EDO15574.1 - 0.027 13.9 1.7 0.12 11.7 0.1 2.3 2 1 0 2 2 2 0 PQQ-like domain Gmad1 PF10647.4 EDO15574.1 - 0.039 13.3 0.0 0.15 11.4 0.0 1.9 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain DUF3589 PF12141.3 EDO15575.1 - 1.7e-95 320.1 7.9 4.8e-95 318.6 5.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) DKCLD PF08068.7 EDO15576.1 - 1e-29 102.1 0.1 4e-29 100.3 0.1 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EDO15576.1 - 4.1e-21 75.7 6.2 6.5e-20 71.8 0.0 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EDO15576.1 - 4e-20 71.3 1.3 7.8e-20 70.3 0.9 1.5 1 0 0 1 1 1 1 PUA domain RNA_polI_A34 PF08208.6 EDO15576.1 - 0.17 11.5 46.9 0.35 10.5 32.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 EDO15576.1 - 0.63 9.9 19.9 0.92 9.4 13.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family YqfQ PF14181.1 EDO15576.1 - 4.6 7.2 24.2 7.8 6.5 16.8 1.4 1 0 0 1 1 1 0 YqfQ-like protein CT47 PF15623.1 EDO15576.1 - 4.6 6.8 26.4 6.2 6.4 18.3 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 HAD PF12710.2 EDO15577.1 - 8.3e-16 58.7 0.1 1.1e-15 58.3 0.1 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EDO15577.1 - 3.4e-07 29.6 0.0 5.6e-07 28.9 0.0 1.3 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 EDO15577.1 - 3.2e-06 27.4 0.0 5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EDO15577.1 - 7.2e-05 22.2 0.0 0.00015 21.1 0.0 1.5 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 EDO15577.1 - 0.0097 16.3 0.4 0.12 12.7 0.0 2.3 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4326 PF14216.1 EDO15577.1 - 0.045 14.3 0.0 0.1 13.1 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4326) SpoU_sub_bind PF08032.7 EDO15577.1 - 0.1 12.7 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding EF-hand_7 PF13499.1 EDO15578.1 - 0.00064 19.7 2.2 0.00064 19.7 1.6 2.5 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 EDO15578.1 - 0.033 13.8 0.9 7.9 6.1 0.0 3.0 2 2 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 EDO15578.1 - 0.062 13.2 4.9 1.6 8.8 0.1 3.3 2 1 1 3 3 3 0 EF-hand domain EF-hand_1 PF00036.27 EDO15578.1 - 0.079 12.3 5.8 0.12 11.7 0.1 3.1 3 0 0 3 3 3 0 EF hand PLA2_B PF01735.13 EDO15579.1 - 3e-84 282.9 8.7 3.2e-69 233.3 1.5 2.4 2 1 0 2 2 2 2 Lysophospholipase catalytic domain ABC_tran PF00005.22 EDO15580.1 - 2.7e-45 154.0 0.1 3.5e-23 82.3 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDO15580.1 - 4.9e-17 62.8 0.1 0.002 18.1 0.0 4.4 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 EDO15580.1 - 2.2e-14 53.2 0.2 4.8e-06 25.9 0.0 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDO15580.1 - 3e-09 37.4 1.4 0.0046 17.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EDO15580.1 - 4.6e-09 35.6 0.0 0.0034 16.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EDO15580.1 - 2.4e-08 34.1 0.0 0.0033 17.5 0.0 4.4 5 1 0 5 5 4 2 AAA domain AAA_17 PF13207.1 EDO15580.1 - 6.3e-08 33.4 0.0 0.0054 17.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EDO15580.1 - 6.4e-08 31.9 0.0 0.00033 19.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 EDO15580.1 - 1.1e-07 31.9 0.0 0.0076 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EDO15580.1 - 3e-07 30.3 0.0 2e-05 24.4 0.0 2.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EDO15580.1 - 5e-07 29.6 0.0 0.0057 16.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.1 EDO15580.1 - 3e-06 27.0 0.1 0.0083 16.0 0.0 3.1 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EDO15580.1 - 3.4e-06 26.7 0.0 0.26 10.6 0.0 3.7 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 EDO15580.1 - 5.7e-06 26.2 0.0 0.14 12.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EDO15580.1 - 7.7e-06 26.4 0.0 0.044 14.2 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein RNA_helicase PF00910.17 EDO15580.1 - 7.8e-06 26.0 0.0 0.095 12.8 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 EDO15580.1 - 8.7e-06 25.9 0.0 0.52 10.5 0.0 4.3 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EDO15580.1 - 1e-05 25.8 0.1 0.021 15.1 0.0 3.5 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.1 EDO15580.1 - 1.1e-05 24.7 0.0 0.57 9.1 0.0 3.8 3 1 0 4 4 4 1 AAA ATPase domain ArgK PF03308.11 EDO15580.1 - 5.4e-05 22.1 0.1 0.19 10.4 0.0 2.4 2 0 0 2 2 2 2 ArgK protein MobB PF03205.9 EDO15580.1 - 7.1e-05 22.5 0.0 0.31 10.7 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ParcG PF10274.4 EDO15580.1 - 7.5e-05 22.7 0.2 0.52 10.1 0.0 2.4 2 0 0 2 2 2 2 Parkin co-regulated protein AAA_16 PF13191.1 EDO15580.1 - 0.00014 21.9 0.0 0.23 11.4 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EDO15580.1 - 0.00017 21.3 0.1 0.3 10.7 0.0 3.4 3 1 0 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 EDO15580.1 - 0.00019 21.3 0.0 2.6 7.9 0.0 3.9 4 0 0 4 4 3 1 AAA domain DUF87 PF01935.12 EDO15580.1 - 0.00022 21.1 0.4 0.31 10.8 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function DUF87 HEAT_2 PF13646.1 EDO15580.1 - 0.00045 20.4 4.4 0.024 14.9 0.0 3.4 1 1 2 3 3 3 1 HEAT repeats AAA_13 PF13166.1 EDO15580.1 - 0.00062 18.3 2.9 2.8 6.3 0.0 4.1 3 1 1 4 4 4 1 AAA domain CLASP_N PF12348.3 EDO15580.1 - 0.00065 19.1 0.9 0.02 14.2 0.3 2.7 2 1 1 3 3 3 1 CLASP N terminal PduV-EutP PF10662.4 EDO15580.1 - 0.0011 18.4 0.0 0.35 10.3 0.0 3.0 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation MutS_V PF00488.16 EDO15580.1 - 0.0012 18.3 0.1 0.38 10.1 0.0 2.5 2 0 0 2 2 2 1 MutS domain V NACHT PF05729.7 EDO15580.1 - 0.0018 17.9 0.0 1.5 8.4 0.0 2.8 3 0 0 3 3 2 1 NACHT domain HEAT_EZ PF13513.1 EDO15580.1 - 0.0042 17.5 10.8 0.61 10.6 0.1 5.1 4 2 2 6 6 4 1 HEAT-like repeat AAA_30 PF13604.1 EDO15580.1 - 0.0043 16.6 0.1 5.7 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Vac14_Fab1_bd PF12755.2 EDO15580.1 - 0.0058 16.9 0.3 2.2 8.7 0.0 3.8 3 1 1 4 4 3 1 Vacuolar 14 Fab1-binding region UME PF08064.8 EDO15580.1 - 0.006 16.5 0.1 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 UME (NUC010) domain cobW PF02492.14 EDO15580.1 - 0.0061 16.0 1.5 1.9 7.9 0.0 3.3 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EDO15580.1 - 0.0064 15.9 0.0 2 7.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Cnd1 PF12717.2 EDO15580.1 - 0.01 15.7 0.7 0.27 11.0 0.0 3.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EDO15580.1 - 0.025 12.9 5.6 0.11 10.8 1.0 2.5 1 1 0 3 3 3 0 Adaptin N terminal region T2SE PF00437.15 EDO15580.1 - 0.025 13.4 0.0 0.27 10.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EDO15580.1 - 0.026 13.6 0.1 4.5 6.3 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.13 EDO15580.1 - 0.034 13.1 0.2 1 8.2 0.0 2.6 3 0 0 3 3 2 0 Septin Mg_chelatase PF01078.16 EDO15580.1 - 0.034 13.2 0.2 1.8 7.6 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF3349 PF11829.3 EDO15580.1 - 0.047 14.1 0.2 0.15 12.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) NTPase_1 PF03266.10 EDO15580.1 - 0.052 13.2 0.1 11 5.6 0.0 2.7 2 0 0 2 2 2 0 NTPase DUF3385 PF11865.3 EDO15580.1 - 0.059 13.2 0.1 25 4.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) FtsK_SpoIIIE PF01580.13 EDO15580.1 - 0.063 12.7 0.2 3 7.2 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EDO15580.1 - 0.07 12.6 0.1 8 5.9 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 EDO15580.1 - 0.13 11.7 0.2 25 4.2 0.0 3.1 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.4 EDO15580.1 - 0.18 10.3 1.8 1.2 7.6 0.0 2.9 4 0 0 4 4 4 0 Predicted ATPase of the ABC class HEAT PF02985.17 EDO15580.1 - 0.46 10.6 5.8 9.7 6.5 0.0 4.5 6 0 0 6 6 3 0 HEAT repeat Pkinase PF00069.20 EDO15581.1 - 3.6e-60 203.3 0.0 7.9e-60 202.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15581.1 - 2.7e-24 85.6 0.1 1.4e-22 80.0 0.1 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO15581.1 - 1.4e-05 24.2 0.2 0.064 12.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EDO15581.1 - 0.0025 16.9 0.2 0.0052 15.8 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO15581.1 - 0.17 11.5 0.0 0.47 10.1 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family AAA_25 PF13481.1 EDO15582.1 - 0.018 14.4 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain Acyltransferase PF01553.16 EDO15583.1 - 8.8e-32 109.3 0.0 1.5e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase FBPase PF00316.15 EDO15584.1 - 1.6e-134 447.8 0.0 1.8e-134 447.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase C2 PF00168.25 EDO15585.1 - 0.014 15.2 0.1 0.016 15.0 0.1 1.4 1 1 0 1 1 1 0 C2 domain Trns_repr_metal PF02583.12 EDO15586.1 - 0.0025 17.9 2.5 0.0063 16.6 1.7 1.7 1 0 0 1 1 1 1 Metal-sensitive transcriptional repressor Reo_sigmaC PF04582.7 EDO15586.1 - 0.022 13.9 2.6 0.039 13.1 1.8 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EDO15586.1 - 0.028 13.1 8.9 0.043 12.4 6.2 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Img2 PF05046.9 EDO15586.1 - 0.032 14.4 1.4 0.069 13.3 1.0 1.5 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) ScpA_ScpB PF02616.9 EDO15586.1 - 0.041 13.4 1.7 0.069 12.7 1.1 1.3 1 0 0 1 1 1 0 ScpA/B protein NPV_P10 PF05531.7 EDO15586.1 - 0.058 13.6 1.2 0.52 10.5 0.2 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Toxin_52 PF15605.1 EDO15586.1 - 0.06 13.2 1.5 0.15 11.9 1.1 1.7 1 0 0 1 1 1 0 Putative toxin 52 DUF948 PF06103.6 EDO15586.1 - 0.063 13.1 0.7 0.19 11.6 0.5 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 EDO15586.1 - 0.091 12.5 5.2 0.042 13.5 1.3 1.9 1 1 1 2 2 2 0 Laminin Domain II MitMem_reg PF13012.1 EDO15586.1 - 0.11 12.6 5.4 7.2 6.7 0.3 2.5 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function DUF972 PF06156.8 EDO15586.1 - 0.21 11.9 12.3 0.056 13.7 5.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF342 PF03961.8 EDO15586.1 - 0.34 9.2 6.3 0.78 8.0 4.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF2730 PF10805.3 EDO15586.1 - 0.4 10.4 6.2 0.92 9.2 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) APG6 PF04111.7 EDO15586.1 - 0.45 9.5 6.2 0.74 8.7 4.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 EDO15586.1 - 0.46 10.3 7.2 0.82 9.5 5.0 1.3 1 0 0 1 1 1 0 Tropomyosin like TBPIP PF07106.8 EDO15586.1 - 1.3 8.5 11.2 0.87 9.1 6.2 1.9 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF812 PF05667.6 EDO15586.1 - 2.3 6.6 10.4 3.5 6.0 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Fib_alpha PF08702.5 EDO15586.1 - 2.6 8.1 9.8 6.1 6.9 6.8 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FCH PF00611.18 EDO15586.1 - 2.8 8.1 6.4 3.7 7.7 2.2 2.4 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain FlxA PF14282.1 EDO15586.1 - 3.9 7.4 14.8 2.1 8.3 7.6 2.1 2 0 0 2 2 2 0 FlxA-like protein Ank_4 PF13637.1 EDO15587.1 - 4.2e-10 39.8 0.1 0.00081 19.8 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO15587.1 - 2.4e-09 37.4 0.6 0.0001 22.5 0.0 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) KilA-N PF04383.8 EDO15587.1 - 1.3e-06 27.9 0.2 1.3e-06 27.9 0.2 3.4 2 2 0 2 2 2 1 KilA-N domain Ank PF00023.25 EDO15587.1 - 1.5e-05 24.5 0.4 0.27 11.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EDO15587.1 - 2e-05 24.6 0.1 0.49 10.7 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO15587.1 - 0.00036 20.4 0.8 3.3 8.2 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Y_phosphatase3 PF13350.1 EDO15588.1 - 1.2e-40 139.4 0.0 2.4e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Abhydrolase_5 PF12695.2 EDO15588.1 - 2.4e-07 30.5 0.0 3.4e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase3C PF13348.1 EDO15588.1 - 5.9e-07 29.5 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Abhydrolase_6 PF12697.2 EDO15588.1 - 9.7e-06 25.6 0.0 0.00012 22.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDO15588.1 - 5e-05 23.0 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Y_phosphatase2 PF03162.8 EDO15588.1 - 0.00032 20.1 1.1 0.0033 16.7 0.4 2.8 1 1 0 1 1 1 1 Tyrosine phosphatase family CodY PF06018.9 EDO15588.1 - 0.06 12.6 0.1 0.28 10.4 0.0 2.1 2 0 0 2 2 2 0 CodY GAF-like domain CRAL_TRIO PF00650.15 EDO15589.1 - 2.8e-42 143.9 0.8 4.4e-42 143.2 0.5 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDO15589.1 - 6.2e-11 42.2 0.1 2.1e-10 40.5 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EDO15589.1 - 2.8e-10 40.3 0.9 6.1e-10 39.1 0.6 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain YicC_N PF03755.8 EDO15589.1 - 0.013 15.3 0.1 0.071 13.0 0.0 2.0 1 1 1 2 2 2 0 YicC-like family, N-terminal region SMC_N PF02463.14 EDO15591.1 - 2.3e-15 56.4 40.4 8.2e-15 54.6 28.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EDO15591.1 - 2e-06 28.2 113.8 1.5e+04 -27.9 78.6 6.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDO15591.1 - 0.00025 20.5 0.0 0.0006 19.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.8 EDO15591.1 - 0.00038 20.4 0.8 0.0022 17.9 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.1 EDO15591.1 - 0.028 14.3 0.0 0.14 12.0 0.0 2.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EDO15591.1 - 0.037 13.4 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EDO15591.1 - 0.084 13.1 0.1 0.084 13.1 0.1 5.7 3 2 0 3 3 3 0 ABC transporter DUF3584 PF12128.3 EDO15591.1 - 3.3 4.9 64.9 0.093 10.0 15.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Uso1_p115_head PF04869.9 EDO15592.1 - 1.1e-114 382.3 0.7 5.3e-114 380.1 0.3 2.5 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region WEMBL PF05701.6 EDO15592.1 - 4.4e-08 32.0 60.1 4.4e-08 32.0 41.6 8.7 1 1 9 10 10 10 4 Weak chloroplast movement under blue light Myosin_tail_1 PF01576.14 EDO15592.1 - 4.9e-07 27.9 85.1 4.9e-07 27.9 59.0 6.0 1 1 4 5 5 5 3 Myosin tail Filament PF00038.16 EDO15592.1 - 5.8e-07 29.2 344.7 0.0037 16.7 24.9 13.4 1 1 5 9 9 9 7 Intermediate filament protein AAA_13 PF13166.1 EDO15592.1 - 5.1e-06 25.2 44.1 5.1e-06 25.2 30.6 10.6 1 1 9 11 11 11 6 AAA domain CENP-F_leu_zip PF10473.4 EDO15592.1 - 7.8e-05 22.5 22.1 7.8e-05 22.5 15.3 20.8 1 1 21 22 22 22 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EDO15592.1 - 0.00044 19.5 6.4 0.00044 19.5 4.5 14.9 1 1 12 16 16 16 8 Reovirus sigma C capsid protein FlaC_arch PF05377.6 EDO15592.1 - 0.0005 19.9 2.3 0.0005 19.9 1.6 29.3 18 9 12 31 31 31 2 Flagella accessory protein C (FlaC) Rad52_Rad22 PF04098.10 EDO15593.1 - 6.3e-39 133.1 0.1 7.6e-39 132.8 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein IKI3 PF04762.7 EDO15594.1 - 0 1150.1 2.5 0 1149.8 1.7 1.1 1 0 0 1 1 1 1 IKI3 family TPR_8 PF13181.1 EDO15594.1 - 0.0071 16.0 8.1 0.12 12.2 0.6 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO15594.1 - 0.02 14.7 1.6 0.12 12.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO15594.1 - 0.18 11.4 2.9 0.46 10.1 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF663 PF04950.7 EDO15595.1 - 1.4e-99 332.8 0.1 1.4e-99 332.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EDO15595.1 - 9.9e-25 85.9 0.0 2.2e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain UQ_con PF00179.21 EDO15597.1 - 2.3e-39 133.9 0.1 2.6e-39 133.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO15597.1 - 6.4e-06 25.9 0.0 8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EDO15597.1 - 0.21 11.2 0.9 0.48 10.1 0.7 1.6 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EDO15597.1 - 1.7 8.5 3.8 4.7 7.1 2.7 1.9 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 EDO15598.1 - 1.1e-52 179.1 18.7 1.4e-52 178.8 12.9 1.1 1 0 0 1 1 1 1 Pex19 protein family NRN1 PF15056.1 EDO15598.1 - 0.027 14.4 0.2 0.16 11.9 0.0 2.3 3 0 0 3 3 3 0 Neuritin protein family SMAP PF15477.1 EDO15598.1 - 0.079 13.2 6.5 1.2 9.4 0.2 2.9 1 1 1 2 2 2 0 Small acidic protein family DUF106 PF01956.11 EDO15598.1 - 0.52 9.8 1.7 1.4 8.4 1.1 1.9 1 1 0 1 1 1 0 Integral membrane protein DUF106 LON PF02190.11 EDO15598.1 - 0.58 9.7 5.8 1.6 8.3 1.1 2.7 1 1 1 2 2 2 0 ATP-dependent protease La (LON) domain PFEMP PF03011.10 EDO15598.1 - 3.2 8.1 8.2 0.7 10.2 0.9 2.5 2 1 0 2 2 2 0 PFEMP DBL domain zf-RING_5 PF14634.1 EDO15599.1 - 1.1e-08 34.6 5.3 2.5e-08 33.5 3.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDO15599.1 - 0.021 14.8 5.7 0.042 13.8 4.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EDO15599.1 - 0.031 14.0 2.0 0.074 12.8 1.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EDO15599.1 - 0.087 12.3 3.9 0.2 11.2 2.7 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Pox_A_type_inc PF04508.7 EDO15599.1 - 0.1 12.4 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat zf-C3HC4_3 PF13920.1 EDO15599.1 - 0.19 11.4 4.7 0.47 10.1 3.2 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO15599.1 - 2.3 8.1 6.3 4.9 7.0 4.4 1.6 1 0 0 1 1 1 0 Ring finger domain ABC2_membrane_3 PF12698.2 EDO15599.1 - 7.6 5.4 8.3 13 4.6 5.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Prok-RING_4 PF14447.1 EDO15599.1 - 8.6 5.9 6.9 38 3.9 3.5 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Sec1 PF00995.18 EDO15600.1 - 6e-67 226.5 17.4 8.2e-67 226.1 12.1 1.0 1 0 0 1 1 1 1 Sec1 family DUF1128 PF06569.6 EDO15600.1 - 0.0021 17.7 0.0 0.0094 15.6 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1128) AAA PF00004.24 EDO15601.1 - 1.6e-90 300.1 0.0 8.4e-44 148.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO15601.1 - 1.2e-12 47.4 0.0 2.2e-05 23.6 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDO15601.1 - 1.5e-11 44.2 0.0 0.00011 21.9 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO15601.1 - 3.3e-11 43.5 0.4 2.4e-05 24.4 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EDO15601.1 - 1.2e-10 41.6 0.7 7.2e-05 22.9 0.0 4.6 2 2 1 3 3 3 1 AAA domain AAA_14 PF13173.1 EDO15601.1 - 8.8e-10 38.5 0.0 0.00015 21.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 EDO15601.1 - 4.9e-09 36.3 0.0 0.002 18.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EDO15601.1 - 7.6e-07 28.1 0.0 0.0051 15.5 0.0 2.7 3 0 0 3 3 3 2 TIP49 C-terminus AAA_33 PF13671.1 EDO15601.1 - 8.8e-07 28.8 0.0 0.0013 18.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EDO15601.1 - 1.7e-06 28.8 0.0 0.032 15.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 EDO15601.1 - 5.5e-06 26.4 0.0 0.072 13.1 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 EDO15601.1 - 1.3e-05 25.0 0.0 0.0046 16.6 0.0 2.8 2 1 0 2 2 2 1 Bacterial dnaA protein Mg_chelatase PF01078.16 EDO15601.1 - 2.6e-05 23.4 0.2 0.11 11.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EDO15601.1 - 3.7e-05 23.8 0.0 0.44 10.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 EDO15601.1 - 5.5e-05 22.6 8.5 0.19 11.0 0.0 4.6 3 2 2 5 5 5 2 AAA domain Zeta_toxin PF06414.7 EDO15601.1 - 7.7e-05 21.8 0.0 0.12 11.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 EDO15601.1 - 9e-05 22.4 0.0 0.19 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EDO15601.1 - 0.00034 20.4 0.0 1.8 8.2 0.0 3.1 2 2 2 4 4 4 2 Archaeal ATPase Rad17 PF03215.10 EDO15601.1 - 0.00043 19.0 0.0 0.025 13.2 0.0 2.9 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 EDO15601.1 - 0.00055 19.6 0.2 0.063 12.9 0.0 3.7 4 0 0 4 4 4 1 NACHT domain CDC48_N PF02359.13 EDO15601.1 - 0.00057 19.7 0.1 0.0026 17.6 0.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain ABC_tran PF00005.22 EDO15601.1 - 0.00076 19.7 0.0 0.087 13.1 0.0 3.0 3 1 0 3 3 2 1 ABC transporter IstB_IS21 PF01695.12 EDO15601.1 - 0.00091 18.6 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_3 PF07726.6 EDO15601.1 - 0.0014 18.2 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDO15601.1 - 0.0014 18.3 8.5 0.0044 16.7 0.1 3.5 4 0 0 4 4 2 1 Part of AAA domain AAA_11 PF13086.1 EDO15601.1 - 0.0016 18.0 0.1 0.97 8.9 0.0 3.3 2 1 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 EDO15601.1 - 0.0023 17.5 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 EDO15601.1 - 0.0043 16.5 0.0 3.8 6.9 0.0 3.8 2 2 0 2 2 2 0 Sigma-54 interaction domain Trigger_C PF05698.9 EDO15601.1 - 0.0047 16.7 1.4 0.29 10.9 0.0 2.5 2 0 0 2 2 2 1 Bacterial trigger factor protein (TF) C-terminus AAA_24 PF13479.1 EDO15601.1 - 0.019 14.5 0.1 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EDO15601.1 - 0.026 13.4 0.0 0.93 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EDO15601.1 - 0.027 14.7 0.8 2.2 8.5 0.0 3.5 4 1 0 4 4 2 0 AAA domain NB-ARC PF00931.17 EDO15601.1 - 0.029 13.2 0.0 3.7 6.3 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain KaiC PF06745.8 EDO15601.1 - 0.03 13.4 1.5 5.5 6.0 0.0 3.3 3 1 1 4 4 3 0 KaiC AAA_30 PF13604.1 EDO15601.1 - 0.036 13.6 0.0 0.43 10.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EDO15601.1 - 0.041 13.4 0.1 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AFG1_ATPase PF03969.11 EDO15601.1 - 0.064 12.0 0.0 0.31 9.8 0.0 2.0 2 0 0 2 2 2 0 AFG1-like ATPase PIH1 PF08190.7 EDO15601.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Vps4_C PF09336.5 EDO15601.1 - 0.11 12.4 0.1 81 3.2 0.0 3.8 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain SbcCD_C PF13558.1 EDO15601.1 - 0.13 12.1 0.3 1.6 8.7 0.0 2.7 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit Dus PF01207.12 EDO15602.1 - 2.8e-41 141.3 0.3 1e-31 109.9 0.0 2.6 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EDO15602.1 - 0.0003 20.3 9.2 0.0041 16.7 0.1 2.9 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GATA PF00320.22 EDO15603.1 - 4.3e-17 61.1 3.4 9.2e-17 60.0 2.3 1.6 1 0 0 1 1 1 1 GATA zinc finger XPG_I PF00867.13 EDO15604.1 - 5.8e-25 87.1 0.0 1.4e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EDO15604.1 - 4.8e-07 29.9 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain BNR PF02012.15 EDO15605.1 - 2.8e-16 56.6 31.9 0.25 11.3 0.0 11.0 9 0 0 9 9 9 8 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EDO15605.1 - 0.0015 18.1 6.5 0.76 9.4 0.0 4.9 5 1 1 6 6 6 2 Mo-co oxidoreductase dimerisation domain PSII_BNR PF14870.1 EDO15605.1 - 0.0025 16.8 8.3 0.3 10.0 0.2 4.5 4 1 1 5 5 5 3 Photosynthesis system II assembly factor YCF48 Cyclin_N PF00134.18 EDO15606.1 - 3.4e-40 136.5 0.4 2.1e-39 133.9 0.1 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDO15606.1 - 2.1e-31 108.2 0.2 7.4e-31 106.5 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain TP53IP5 PF15331.1 EDO15606.1 - 0.52 10.2 8.0 0.35 10.7 4.1 1.6 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF1548 PF07579.6 EDO15606.1 - 0.66 10.0 5.1 0.38 10.8 0.5 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) Cyclin_N PF00134.18 EDO15607.1 - 6.1e-40 135.7 1.4 2.6e-38 130.4 1.0 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDO15607.1 - 3.5e-09 36.6 0.2 5.2e-08 32.8 0.0 2.4 2 1 0 2 2 2 1 Cyclin, C-terminal domain TPR_1 PF00515.23 EDO15608.1 - 2.1e-39 131.5 33.7 1.4e-05 24.4 0.1 10.7 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 EDO15608.1 - 1.8e-37 124.2 28.3 9.4e-05 22.0 0.0 10.2 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 EDO15608.1 - 2.8e-37 126.1 24.6 9.1e-10 38.0 0.7 6.4 3 2 1 6 6 6 5 TPR repeat TPR_12 PF13424.1 EDO15608.1 - 8.3e-27 92.9 28.5 2.8e-08 33.5 0.5 7.2 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_8 PF13181.1 EDO15608.1 - 3.7e-25 85.7 23.1 0.011 15.5 0.0 9.9 7 2 2 9 9 9 9 Tetratricopeptide repeat TPR_17 PF13431.1 EDO15608.1 - 1.6e-23 80.9 24.8 0.00053 19.9 0.1 10.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 EDO15608.1 - 1e-21 76.9 14.5 2.2e-05 24.9 0.1 6.4 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EDO15608.1 - 1.3e-21 75.0 10.5 0.012 16.1 0.1 9.5 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_7 PF13176.1 EDO15608.1 - 4.6e-19 66.6 14.1 0.0019 17.8 0.1 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EDO15608.1 - 1.8e-14 53.8 14.0 0.0087 16.3 0.0 5.7 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.1 EDO15608.1 - 7.1e-13 48.0 9.8 3.1 8.4 0.1 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EDO15608.1 - 5.8e-11 42.0 7.7 0.017 14.9 0.0 5.5 3 1 3 6 6 6 5 Tetratricopeptide repeat Apc3 PF12895.2 EDO15608.1 - 1.4e-09 37.9 13.2 0.001 19.1 0.4 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EDO15608.1 - 1.2e-08 34.3 11.2 0.0073 15.3 0.1 5.3 1 1 4 6 6 6 3 Tetratricopeptide repeat MIT PF04212.13 EDO15608.1 - 0.0077 16.0 11.5 1.3 8.9 0.2 4.9 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EDO15608.1 - 0.053 13.4 12.4 0.16 11.9 0.0 5.5 6 1 1 7 7 7 0 Tetratricopeptide repeat Ubiq-assoc PF09145.5 EDO15608.1 - 0.1 12.5 0.6 3.4 7.6 0.0 3.0 3 0 0 3 3 3 0 Ubiquitin-associated SNF2_N PF00176.18 EDO15609.1 - 1e-73 247.7 0.4 1.6e-73 247.1 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO15609.1 - 4e-11 42.6 0.0 1.2e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EDO15609.1 - 5.9e-09 35.4 11.5 5.9e-09 35.4 7.9 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EDO15609.1 - 2.9e-08 33.3 0.0 5.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 EDO15609.1 - 1.7e-05 24.5 9.3 1.7e-05 24.5 6.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDO15609.1 - 3.6e-05 23.7 9.6 3.6e-05 23.7 6.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO15609.1 - 0.00043 20.0 10.3 0.00043 20.0 7.1 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EDO15609.1 - 0.00063 19.3 7.4 0.00063 19.3 5.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO15609.1 - 0.0067 16.1 10.0 0.0067 16.1 6.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Zn_Tnp_IS91 PF14319.1 EDO15609.1 - 0.28 10.7 11.9 0.46 10.0 1.2 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_6 PF14835.1 EDO15609.1 - 0.31 10.8 3.4 0.91 9.3 2.4 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein AMP-binding PF00501.23 EDO15610.1 - 1.9e-74 250.5 0.0 2.4e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EDO15610.1 - 4.6e-69 232.0 0.0 7e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EDO15610.1 - 7.8e-15 54.8 0.0 1.9e-14 53.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EDO15610.1 - 6.6e-09 35.5 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EDO15610.1 - 9.8e-09 36.0 0.0 5.1e-08 33.7 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Not3 PF04065.10 EDO15611.1 - 9.4e-78 260.6 43.3 2.6e-76 255.9 26.6 3.1 2 1 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EDO15611.1 - 1.1e-24 86.8 16.4 5.6e-24 84.5 9.1 4.1 3 1 1 4 4 4 2 NOT2 / NOT3 / NOT5 family Ish1 PF10281.4 EDO15611.1 - 0.29 11.2 4.3 34 4.6 0.0 4.0 3 0 0 3 3 3 0 Putative stress-responsive nuclear envelope protein Transketolase_N PF00456.16 EDO15612.1 - 2.4e-146 486.8 0.0 5.3e-146 485.6 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EDO15612.1 - 5.1e-45 153.1 0.0 8.5e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDO15612.1 - 3.4e-10 39.9 0.0 6.2e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 EDO15612.1 - 0.0001 21.1 0.0 0.00016 20.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EDO15612.1 - 0.00028 19.9 0.0 0.0025 16.8 0.0 2.0 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase XRN_N PF03159.13 EDO15613.1 - 1.1e-96 322.8 0.1 2.2e-96 321.8 0.1 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Zip PF02535.17 EDO15614.1 - 3.8e-64 216.7 3.7 4.5e-64 216.4 2.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Mito_carr PF00153.22 EDO15615.1 - 9.4e-77 252.8 0.5 3.8e-26 90.6 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein MA3 PF02847.12 EDO15615.1 - 0.02 14.6 0.0 1.1 8.9 0.0 3.2 2 0 0 2 2 2 0 MA3 domain MRG PF05712.8 EDO15616.1 - 6.5e-44 149.1 0.4 6.5e-44 149.1 0.2 1.7 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 EDO15616.1 - 1.8e-07 30.7 0.0 4.1e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Cucumo_2B PF03263.8 EDO15616.1 - 0.14 12.4 6.7 0.69 10.2 4.7 2.1 1 1 0 1 1 1 0 Cucumovirus protein 2B DUF349 PF03993.7 EDO15616.1 - 0.15 12.2 4.6 0.14 12.3 2.1 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF3573 PF12097.3 EDO15616.1 - 6.7 5.2 9.1 9.5 4.7 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Pkinase PF00069.20 EDO15617.1 - 1.2e-28 100.0 0.2 2.7e-28 98.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15617.1 - 7.3e-09 35.0 0.0 1.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DIL PF01843.14 EDO15619.1 - 6.6e-08 32.3 0.8 2.9e-07 30.3 0.2 2.2 2 0 0 2 2 2 1 DIL domain RAG2_PHD PF13341.1 EDO15619.1 - 0.068 13.1 0.1 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 RAG2 PHD domain eIF-1a PF01176.14 EDO15620.1 - 3.2e-27 93.7 0.3 4.4e-27 93.3 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 EDO15620.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain RabGAP-TBC PF00566.13 EDO15621.1 - 0.14 11.5 3.4 0.22 10.9 2.3 1.3 1 0 0 1 1 1 0 Rab-GTPase-TBC domain DUF4257 PF14074.1 EDO15621.1 - 0.28 10.8 3.5 0.2 11.3 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4257) Glyco_hydro_32N PF00251.15 EDO15622.1 - 9.7e-85 284.6 10.0 1.4e-84 284.1 6.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EDO15622.1 - 2e-09 37.6 0.0 1.7e-08 34.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal zf-C2H2 PF00096.21 EDO15623.1 - 6e-08 32.5 31.5 0.0018 18.5 0.8 5.4 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO15623.1 - 9.1e-06 25.6 26.8 0.022 15.0 0.5 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO15623.1 - 1.1e-05 25.4 9.0 7.7e-05 22.7 1.0 5.4 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDO15623.1 - 0.0019 18.3 0.8 0.0019 18.3 0.5 3.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding SPOUT_MTase PF02590.12 EDO15623.1 - 0.052 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase GAGA PF09237.6 EDO15623.1 - 0.056 13.0 1.0 0.14 11.7 0.7 1.6 1 0 0 1 1 1 0 GAGA factor zf-met PF12874.2 EDO15623.1 - 0.76 10.0 6.3 0.82 9.9 0.3 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Sec63 PF02889.11 EDO15624.1 - 3.5e-52 177.5 0.8 6.3e-52 176.7 0.6 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EDO15624.1 - 5.8e-26 90.9 0.0 1.4e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EDO15624.1 - 2.4e-11 43.7 1.2 5.3e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDO15624.1 - 7.3e-10 38.5 0.0 2.5e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDO15624.1 - 0.00013 20.8 0.1 0.00036 19.4 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EDO15624.1 - 0.00015 21.9 0.0 0.00054 20.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO15624.1 - 0.049 13.3 0.0 0.24 11.1 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain HHH_5 PF14520.1 EDO15624.1 - 0.094 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF2420 PF10336.4 EDO15625.1 - 5.8e-44 148.3 0.8 9.6e-44 147.6 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) DUF4221 PF13970.1 EDO15625.1 - 0.15 11.3 2.2 8 5.6 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4221) eIF3_subunit PF08597.5 EDO15626.1 - 3.4e-63 213.4 18.6 4e-63 213.2 12.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Ndc80_HEC PF03801.8 EDO15627.1 - 1.4e-57 193.5 3.8 4.4e-57 191.9 2.6 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family YqbF PF14553.1 EDO15627.1 - 0.55 9.9 5.0 15 5.3 0.3 3.2 3 0 0 3 3 3 0 YqbF, hypothetical protein domain SRP40_C PF05022.7 EDO15628.1 - 9.6e-30 102.9 3.9 2.5e-29 101.5 2.7 1.8 1 0 0 1 1 1 1 SRP40, C-terminal domain DUF3336 PF11815.3 EDO15629.1 - 5.3e-42 142.7 2.7 5.3e-42 142.7 1.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EDO15629.1 - 1.2e-29 103.6 0.0 2.7e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase U3_snoRNA_assoc PF08297.6 EDO15630.1 - 1.7e-23 82.6 8.1 1.7e-23 82.6 5.6 2.5 2 1 0 2 2 2 1 U3 snoRNA associated Asp-B-Hydro_N PF05279.6 EDO15630.1 - 2.9 7.6 17.9 3.6 7.3 12.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region G-patch_2 PF12656.2 EDO15630.1 - 3.7 7.4 6.4 3.4 7.5 0.6 3.0 3 0 0 3 3 3 0 DExH-box splicing factor binding site THF_DHG_CYH PF00763.18 EDO15631.1 - 7.1e-20 71.1 0.0 4.2e-19 68.7 0.0 2.1 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EDO15631.1 - 3.5e-16 58.6 0.0 1.2e-10 40.7 0.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lactamase_B_2 PF12706.2 EDO15632.1 - 6.9e-37 126.8 0.1 1.2e-36 126.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EDO15632.1 - 8.1e-24 82.8 0.0 1.7e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EDO15632.1 - 2.4e-05 24.0 0.0 4.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Bacteriocin_IIi PF11758.3 EDO15632.1 - 0.13 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin Vps5 PF09325.5 EDO15633.1 - 3e-69 232.8 15.5 5.6e-69 231.9 10.8 1.5 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EDO15633.1 - 4.2e-21 74.8 2.9 6.7e-21 74.2 0.1 2.7 3 0 0 3 3 3 1 PX domain Occludin_ELL PF07303.8 EDO15633.1 - 2.1 9.1 9.6 9.2 7.0 0.2 3.6 3 0 0 3 3 3 0 Occludin homology domain GST_N_2 PF13409.1 EDO15635.1 - 4e-22 77.9 0.0 1.4e-21 76.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDO15635.1 - 6.2e-11 42.0 0.0 1.8e-10 40.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDO15635.1 - 0.0003 20.9 0.0 0.7 10.1 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDO15635.1 - 0.091 12.7 0.5 0.63 10.0 0.4 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EDO15636.1 - 2e-22 78.9 0.0 9.2e-22 76.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDO15636.1 - 1.8e-10 40.5 0.0 3.8e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDO15636.1 - 0.00092 19.3 0.1 0.91 9.7 0.0 2.7 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EDO15636.1 - 0.14 12.1 0.6 2.6 8.0 0.5 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cytochrom_C1 PF02167.10 EDO15637.1 - 6.2e-84 281.0 0.0 7.4e-84 280.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EDO15637.1 - 0.00042 20.4 0.0 0.00094 19.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EDO15637.1 - 0.00068 20.4 0.2 0.0019 19.0 0.1 1.8 1 1 0 1 1 1 1 Cytochrome c Pkinase PF00069.20 EDO15639.1 - 1.7e-53 181.4 0.0 2.1e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15639.1 - 1.7e-17 63.3 0.0 2.5e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO15639.1 - 2.9e-07 30.4 0.0 3e-06 27.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EDO15639.1 - 0.0058 16.2 0.1 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Nrap PF03813.9 EDO15642.1 - 0 1196.1 10.8 0 1195.9 7.5 1.0 1 0 0 1 1 1 1 Nrap protein Sigma70_ner PF04546.8 EDO15642.1 - 0.025 14.2 16.2 0.01 15.4 8.3 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region Vfa1 PF08432.5 EDO15642.1 - 0.066 13.2 9.7 0.15 12.0 6.7 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RXT2_N PF08595.6 EDO15642.1 - 0.22 11.3 10.3 0.67 9.7 7.2 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.9 EDO15642.1 - 0.27 9.2 10.0 0.42 8.5 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.1 EDO15642.1 - 3.4 8.0 16.1 6.5 7.1 11.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTV_NS2 PF04514.7 EDO15642.1 - 3.5 6.4 8.3 5.4 5.7 5.8 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2457 PF10446.4 EDO15642.1 - 4.6 5.8 24.7 8.6 4.9 17.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RNA_pol_A_bac PF01000.21 EDO15644.1 - 3.6e-30 104.4 0.0 8.9e-30 103.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDO15644.1 - 6.9e-17 60.3 0.0 1.1e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RepA_C PF04796.7 EDO15645.1 - 0.044 13.3 0.7 0.089 12.3 0.5 1.5 1 0 0 1 1 1 0 Plasmid encoded RepA protein Lyase_8 PF02278.13 EDO15646.1 - 0.92 8.8 10.3 0.036 13.4 2.8 1.7 2 0 0 2 2 2 0 Polysaccharide lyase family 8, super-sandwich domain Caveolin PF01146.12 EDO15646.1 - 1.2 8.6 7.8 0.039 13.5 1.3 1.5 2 0 0 2 2 2 0 Caveolin Pmp3 PF01679.12 EDO15647.1 - 4e-19 68.0 5.4 4.3e-19 67.9 3.7 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DEAD PF00270.24 EDO15648.1 - 4.4e-35 120.6 0.7 7.3e-34 116.6 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO15648.1 - 7.9e-27 92.9 0.1 1.5e-26 92.0 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO15648.1 - 0.00057 19.7 0.9 0.0012 18.6 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EDO15648.1 - 0.0056 16.6 0.0 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain AAA_30 PF13604.1 EDO15648.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain XRN_N PF03159.13 EDO15649.1 - 1.4e-108 361.7 0.3 1.6e-107 358.2 0.0 2.4 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Acyltransferase PF01553.16 EDO15650.1 - 4.8e-07 29.2 0.0 1.1e-05 24.9 0.0 2.6 1 1 0 1 1 1 1 Acyltransferase TRAPP PF04051.11 EDO15651.1 - 1.3e-38 131.9 0.0 1.6e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF111 PF01969.12 EDO15651.1 - 0.16 10.7 0.0 1.4 7.6 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF111 Nro1 PF12753.2 EDO15652.1 - 4.1e-159 529.8 22.0 4.7e-159 529.6 15.2 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 Usp PF00582.21 EDO15652.1 - 0.12 12.6 4.3 4.7 7.4 0.3 2.5 2 0 0 2 2 2 0 Universal stress protein family DUF3359 PF11839.3 EDO15652.1 - 0.15 12.4 2.2 13 6.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) DUF2408 PF10303.4 EDO15652.1 - 0.16 12.1 0.1 0.16 12.1 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) TPR_12 PF13424.1 EDO15652.1 - 0.54 10.2 5.4 0.44 10.5 1.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Hydrolase_like PF13242.1 EDO15653.1 - 3e-26 90.9 0.0 6.8e-26 89.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EDO15653.1 - 7.6e-26 89.9 0.0 2.1e-25 88.5 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDO15653.1 - 0.00011 22.4 0.0 0.95 9.6 0.0 3.0 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO15653.1 - 0.046 14.1 0.0 1.1 9.6 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-AN1 PF01428.11 EDO15654.1 - 1.3e-08 34.5 11.3 1.3e-08 34.5 7.8 1.6 2 0 0 2 2 2 1 AN1-like Zinc finger Flavoprotein PF02441.14 EDO15655.1 - 9.9e-41 138.4 0.1 2.9e-40 136.9 0.0 1.8 1 1 0 1 1 1 1 Flavoprotein Nop14 PF04147.7 EDO15655.1 - 3.4 5.4 29.5 51 1.5 0.0 2.2 2 0 0 2 2 2 0 Nop14-like family NOB1_Zn_bind PF08772.6 EDO15656.1 - 1e-26 92.4 1.8 1.3e-26 92.1 0.2 2.0 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like Integrase_AP2 PF14657.1 EDO15656.1 - 0.0025 17.5 6.4 0.071 12.9 5.6 2.4 2 0 0 2 2 2 1 AP2-like DNA-binding integrase domain DUF3475 PF11961.3 EDO15656.1 - 0.0087 15.8 0.1 1.7 8.5 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3475) DUF2011 PF09428.5 EDO15656.1 - 0.26 11.1 13.8 0.32 10.8 6.2 2.3 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) DUF2340 PF10209.4 EDO15657.1 - 2e-57 192.6 2.7 2.4e-57 192.3 1.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Peptidase_C13 PF01650.13 EDO15657.1 - 0.031 13.5 0.4 0.037 13.3 0.3 1.2 1 0 0 1 1 1 0 Peptidase C13 family Imm20 PF15568.1 EDO15657.1 - 0.085 12.7 0.4 1.8 8.4 0.1 2.0 2 0 0 2 2 2 0 Immunity protein 20 DUF676 PF05057.9 EDO15658.1 - 7.5e-47 159.4 0.7 1.2e-46 158.7 0.5 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EDO15658.1 - 0.00012 21.7 0.1 0.00022 20.8 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EDO15658.1 - 0.0044 16.7 0.0 0.0083 15.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EDO15658.1 - 0.034 13.7 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Lipase_2 PF01674.13 EDO15658.1 - 0.087 12.1 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) bZIP_1 PF00170.16 EDO15660.1 - 1.3e-08 34.6 8.8 2.6e-08 33.7 6.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDO15660.1 - 0.011 15.4 8.9 0.029 14.2 6.2 1.8 1 0 0 1 1 1 0 Basic region leucine zipper DUF3736 PF12540.3 EDO15660.1 - 0.028 14.6 5.4 0.062 13.5 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) TFIIA PF03153.8 EDO15660.1 - 1.4 8.7 16.6 1.9 8.2 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 EDO15660.1 - 2.2 6.4 14.1 2.7 6.1 9.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Cellulase PF00150.13 EDO15661.1 - 1.4e-07 31.0 16.9 8.2e-07 28.5 11.7 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CK_II_beta PF01214.13 EDO15662.1 - 3.8e-71 238.4 0.0 4.4e-71 238.1 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Lactamase_B PF00753.22 EDO15663.1 - 9.1e-24 84.1 0.0 1.2e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDO15663.1 - 6.1e-08 32.4 0.0 8.4e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EDO15663.1 - 0.056 13.1 0.0 0.084 12.5 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain S_100 PF01023.14 EDO15663.1 - 0.16 11.3 0.3 0.32 10.3 0.2 1.5 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain RNase_PH PF01138.16 EDO15664.1 - 2e-20 73.4 0.0 3.2e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDO15664.1 - 5.7e-11 42.1 0.2 1.6e-09 37.5 0.0 2.3 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 DUF3589 PF12141.3 EDO15665.1 - 0.0032 15.7 0.0 0.0032 15.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3589) TRAM_LAG1_CLN8 PF03798.11 EDO15666.1 - 3.5e-32 111.5 22.1 3.5e-32 111.5 15.3 2.1 2 0 0 2 2 2 2 TLC domain TRAM_LAG1_CLN8 PF03798.11 EDO15667.1 - 2.4e-32 112.1 15.8 2.4e-32 112.1 11.0 1.9 2 0 0 2 2 2 1 TLC domain Peptidase_M48 PF01435.13 EDO15668.1 - 2.7e-47 161.2 0.1 4.3e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.4 EDO15668.1 - 0.0039 16.5 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) Ilm1 PF10311.4 EDO15669.1 - 5.2e-46 156.1 12.0 7.6e-46 155.6 8.3 1.2 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 CDC45 PF02724.9 EDO15669.1 - 0.0018 16.4 0.3 0.0021 16.1 0.2 1.1 1 0 0 1 1 1 1 CDC45-like protein VID27 PF08553.5 EDO15669.1 - 0.048 11.8 9.0 0.054 11.7 6.3 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein AAA_23 PF13476.1 EDO15669.1 - 6.8 6.9 11.8 8.5 6.6 8.2 1.1 1 0 0 1 1 1 0 AAA domain JmjC PF02373.17 EDO15670.1 - 2.5e-36 124.3 0.5 6.9e-36 122.9 0.4 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EDO15670.1 - 6.3e-10 38.3 0.0 6.3e-10 38.3 0.0 2.6 3 0 0 3 3 3 1 jmjN domain PHD PF00628.24 EDO15670.1 - 1.3e-06 27.9 19.4 2.2e-06 27.2 7.7 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 EDO15670.1 - 0.062 12.6 17.1 0.018 14.3 4.5 2.8 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 EDO15670.1 - 3 7.6 16.8 0.13 11.9 6.4 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CENP-B_dimeris PF09026.5 EDO15670.1 - 3.7 7.8 15.7 25 5.1 0.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ATP-synt_ab PF00006.20 EDO15671.1 - 6.8e-63 212.0 0.0 1e-62 211.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDO15671.1 - 1.6e-26 93.0 0.2 2.5e-26 92.3 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDO15671.1 - 2.8e-22 78.6 1.8 2.8e-22 78.6 1.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 EDO15671.1 - 0.0023 17.1 0.2 0.0038 16.3 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EDO15671.1 - 0.0031 16.9 0.0 0.01 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EDO15671.1 - 0.0036 17.0 0.1 0.56 9.9 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EDO15671.1 - 0.02 13.7 0.5 0.52 9.1 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 EDO15671.1 - 0.023 14.3 0.2 0.073 12.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EDO15671.1 - 0.047 13.6 0.4 0.18 11.7 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EDO15671.1 - 0.054 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 EDO15671.1 - 0.058 13.5 0.0 0.63 10.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO15671.1 - 0.1 12.7 0.0 0.36 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDO15671.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EDO15671.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase GCV_T PF01571.16 EDO15672.1 - 2.6e-06 26.9 0.0 0.26 10.6 0.0 3.3 3 0 0 3 3 3 3 Aminomethyltransferase folate-binding domain Ribosomal_S7 PF00177.16 EDO15673.1 - 8.8e-40 135.6 1.9 1.3e-39 135.1 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MFS_1 PF07690.11 EDO15674.1 - 1e-18 67.1 14.6 3.2e-10 39.2 13.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EDO15674.1 - 0.0032 16.0 0.1 0.0032 16.0 0.1 2.7 1 1 2 3 3 3 2 Vacuole effluxer Atg22 like Fungal_trans PF04082.13 EDO15675.1 - 3.2e-10 39.3 0.2 6.6e-10 38.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO15675.1 - 1.7e-07 31.0 10.2 3.2e-07 30.1 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.22 EDO15676.1 - 1.2e-38 132.4 0.0 2.4e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EDO15676.1 - 3.1e-36 123.2 0.3 7e-36 122.1 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EDO15676.1 - 1.3e-11 44.4 0.6 5.7e-11 42.3 0.4 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO15676.1 - 0.0064 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDO15676.1 - 0.093 12.5 0.1 0.82 9.4 0.0 2.5 3 0 0 3 3 3 0 Dynamin family ORC4_C PF14629.1 EDO15677.1 - 2.3e-31 108.8 1.5 4e-31 107.9 1.1 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EDO15677.1 - 5.3e-09 36.3 0.0 9.2e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO15677.1 - 2.1e-06 27.8 0.1 5.2e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain Kelch_4 PF13418.1 EDO15678.1 - 0.01 15.6 2.2 0.51 10.1 0.0 3.8 4 0 0 4 4 4 0 Galactose oxidase, central domain Ras PF00071.17 EDO15679.1 - 2.7e-55 186.1 0.0 3.2e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO15679.1 - 6e-16 59.0 0.0 9.1e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO15679.1 - 8.7e-07 28.3 0.0 1.2e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDO15679.1 - 0.02 14.0 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EDO15679.1 - 0.056 12.6 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PAPS_reduct PF01507.14 EDO15680.1 - 2.1e-40 138.3 0.0 2.8e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Med10 PF09748.4 EDO15681.1 - 3.3e-45 153.0 0.9 3.9e-45 152.8 0.6 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex AAA_13 PF13166.1 EDO15681.1 - 0.0015 17.1 0.2 0.0018 16.8 0.2 1.0 1 0 0 1 1 1 1 AAA domain DASH_Dad2 PF08654.5 EDO15681.1 - 0.012 15.6 0.1 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad2 PBS_linker_poly PF00427.16 EDO15681.1 - 0.037 13.6 0.1 0.069 12.8 0.1 1.6 1 1 0 1 1 1 0 Phycobilisome Linker polypeptide EzrA PF06160.7 EDO15681.1 - 0.056 11.6 0.4 0.074 11.2 0.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF2203 PF09969.4 EDO15681.1 - 0.065 13.4 0.8 12 6.1 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF972 PF06156.8 EDO15681.1 - 0.17 12.2 0.4 0.87 9.9 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) NPV_P10 PF05531.7 EDO15681.1 - 0.2 11.9 3.9 0.33 11.2 0.2 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein WD40 PF00400.27 EDO15682.1 - 3.3e-09 36.2 0.3 0.0028 17.4 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Menin PF05053.8 EDO15682.1 - 0.049 11.8 10.2 0.081 11.0 7.1 1.3 1 0 0 1 1 1 0 Menin Arrestin_C PF02752.17 EDO15683.1 - 4.7e-26 91.5 0.3 1.3e-24 86.8 0.0 2.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EDO15683.1 - 5.4e-09 36.0 0.1 1.7e-07 31.1 0.0 2.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EDO15683.1 - 0.00096 18.6 0.0 0.0046 16.4 0.0 2.1 2 0 0 2 2 2 1 Arrestin_N terminal like RRM_1 PF00076.17 EDO15685.1 - 1.8e-41 139.6 14.8 1.2e-17 63.2 0.5 5.4 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO15685.1 - 4.1e-26 90.7 1.9 3e-10 39.9 0.0 4.9 4 1 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO15685.1 - 1.2e-15 57.0 6.3 3e-06 26.9 0.7 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO15685.1 - 0.00072 19.3 8.0 0.035 13.9 0.1 3.5 4 0 0 4 4 4 2 RNA binding motif DUF500 PF04366.7 EDO15686.1 - 1.4e-45 153.7 0.1 2.3e-45 153.0 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EDO15686.1 - 1.2e-16 59.7 0.1 2.5e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO15686.1 - 2.9e-13 49.1 0.0 5.9e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDO15686.1 - 7.1e-11 41.4 0.0 1.5e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.3 EDO15686.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) ProRS-C_1 PF09180.6 EDO15687.1 - 1.5e-26 92.0 2.1 3.7e-26 90.8 1.5 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EDO15687.1 - 7e-22 77.8 0.1 1.2e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO15687.1 - 1.1e-19 70.1 0.5 4.2e-19 68.2 0.2 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.10 EDO15687.1 - 0.017 14.9 0.1 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain Acetyltransf_13 PF13880.1 EDO15688.1 - 1.9e-21 75.5 0.0 5.8e-21 74.0 0.0 1.8 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EDO15688.1 - 6.3e-14 51.2 1.1 1.2e-13 50.4 0.7 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EDO15688.1 - 0.019 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO15688.1 - 0.039 14.1 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Prp31_C PF09785.4 EDO15688.1 - 0.04 14.3 0.1 0.069 13.5 0.1 1.3 1 0 0 1 1 1 0 Prp31 C terminal domain PhnA_Zn_Ribbon PF08274.7 EDO15688.1 - 0.17 11.6 1.1 0.27 11.0 0.1 1.8 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DSPn PF14671.1 EDO15689.1 - 4.7e-51 172.5 0.1 1.6e-50 170.7 0.1 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EDO15689.1 - 8.6e-24 83.6 0.0 4.9e-23 81.1 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDO15689.1 - 1e-05 24.9 0.6 7.1e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EDO15689.1 - 0.0021 18.0 0.0 0.0059 16.6 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 EDO15689.1 - 0.0038 16.6 0.1 0.0079 15.6 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EDO15689.1 - 0.026 14.7 0.0 0.073 13.3 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family IncA PF04156.9 EDO15690.1 - 0.00012 21.7 11.2 0.00012 21.7 7.7 4.8 1 1 1 3 3 3 2 IncA protein PAS_9 PF13426.1 EDO15690.1 - 0.021 15.1 1.1 0.16 12.3 0.1 2.7 2 0 0 2 2 2 0 PAS domain DUF869 PF05911.6 EDO15690.1 - 0.26 9.4 65.6 0.48 8.6 15.9 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EDO15690.1 - 6.3 5.8 12.2 1.6 7.8 2.0 2.5 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Dynein_light PF01221.13 EDO15690.1 - 6.9 6.7 9.5 6.8 6.7 0.1 4.0 4 0 0 4 4 4 0 Dynein light chain type 1 DUF730 PF05325.6 EDO15690.1 - 7.2 6.4 14.6 0.37 10.6 1.3 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF730) Macoilin PF09726.4 EDO15691.1 - 2.5 6.2 13.1 3.1 5.9 9.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Strep_his_triad PF04270.8 EDO15693.1 - 0.00097 18.8 5.4 14 5.4 0.0 6.1 2 1 5 7 7 7 1 Streptococcal histidine triad protein Phi-29_GP16_7 PF06720.6 EDO15693.1 - 0.036 13.7 0.6 36 4.0 0.0 4.1 1 1 5 6 6 6 0 Bacteriophage phi-29 early protein GP16.7 DUF1869 PF08956.5 EDO15693.1 - 0.95 9.1 9.1 67 3.1 0.1 5.0 1 1 5 6 6 6 0 Domain of unknown function (DUF1869) Neural_ProG_Cyt PF06567.6 EDO15693.1 - 7.9 6.6 6.3 31 4.7 0.2 3.6 1 1 3 4 4 4 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain Strep_his_triad PF04270.8 EDO15694.1 - 0.0007 19.2 3.6 15 5.4 0.0 5.6 3 2 4 7 7 7 3 Streptococcal histidine triad protein Strep_his_triad PF04270.8 EDO15695.1 - 0.014 15.0 8.1 13 5.6 0.0 6.3 2 1 7 9 9 9 0 Streptococcal histidine triad protein DUF1869 PF08956.5 EDO15695.1 - 0.069 12.7 18.1 20 4.8 0.2 6.7 1 1 5 7 7 7 0 Domain of unknown function (DUF1869) Enterotoxin_ST PF02048.11 EDO15695.1 - 7.2 6.9 28.4 58 4.0 0.2 8.1 2 2 7 9 9 9 0 Heat-stable enterotoxin ST Flocculin PF00624.13 EDO15696.1 - 3.5e-163 529.2 427.9 5e-15 55.0 8.6 24.2 21 1 1 22 22 22 21 Flocculin repeat Flocculin PF00624.13 EDO15697.1 - 1.2e-49 165.9 239.1 1.6e-11 43.8 4.7 13.8 12 2 0 12 12 12 10 Flocculin repeat NAD_binding_6 PF08030.7 EDO15698.1 - 6.2e-27 94.4 0.0 1.1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EDO15698.1 - 1.2e-21 76.4 0.0 3e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EDO15698.1 - 1.4e-19 70.3 15.0 1.4e-19 70.3 10.4 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component Aminotran_4 PF01063.14 EDO15699.1 - 2.6e-29 102.3 0.0 3.6e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV SET PF00856.23 EDO15701.1 - 1.1e-17 64.7 0.0 1.9e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 SET domain Pkinase PF00069.20 EDO15702.1 - 1e-65 221.5 0.0 1.5e-65 220.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15702.1 - 1.5e-31 109.4 0.0 2.2e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EDO15702.1 - 1.5e-08 35.0 0.7 4.5e-08 33.4 0.5 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDO15702.1 - 1.9e-07 30.3 0.1 3.5e-07 29.4 0.0 1.4 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 EDO15702.1 - 0.069 12.4 0.2 0.52 9.6 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL C2 PF00168.25 EDO15702.1 - 0.077 12.8 0.5 7.1 6.5 0.1 2.9 3 0 0 3 3 3 0 C2 domain APH PF01636.18 EDO15702.1 - 0.12 12.0 0.0 0.85 9.2 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.15 EDO15703.1 - 2.6e-122 408.7 0.0 3.3e-122 408.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Metallophos PF00149.23 EDO15704.1 - 5.8e-12 45.4 2.2 1.1e-11 44.5 1.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mgm101p PF06420.7 EDO15705.1 - 1.1e-86 288.4 0.0 1.4e-86 288.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 PMT PF02366.13 EDO15706.1 - 1.8e-76 256.7 22.7 1.8e-76 256.7 15.7 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDO15706.1 - 8.8e-26 90.6 1.7 1.5e-25 89.8 1.2 1.3 1 0 0 1 1 1 1 MIR domain DUF3671 PF12420.3 EDO15706.1 - 2.1 8.3 7.7 4.8 7.2 0.4 3.1 2 0 0 2 2 2 0 Protein of unknown function NUDIX PF00293.23 EDO15707.1 - 2.4e-08 33.6 0.0 4.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DHHA2 PF02833.9 EDO15708.1 - 2.2e-29 102.2 0.3 4.4e-29 101.2 0.1 1.5 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.15 EDO15708.1 - 1.7e-09 37.4 0.0 4.3e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 DHH family DUF4138 PF13595.1 EDO15708.1 - 0.0019 17.2 0.6 1.1 8.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4138) HECT_2 PF09814.4 EDO15709.1 - 9.5e-77 258.0 0.6 1.1e-76 257.9 0.4 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TPR_11 PF13414.1 EDO15710.1 - 0.3 10.7 1.4 2.4 7.8 0.5 2.2 1 1 1 2 2 2 0 TPR repeat Chalcone PF02431.10 EDO15712.1 - 2.5e-55 186.9 0.0 3.3e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase DUF2454 PF10521.4 EDO15713.1 - 2.2e-78 263.0 1.2 2.9e-78 262.7 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) ATP-synt_J PF04911.7 EDO15714.1 - 5.1e-26 89.8 0.1 5.7e-26 89.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase j chain Myb_DNA-bind_5 PF13873.1 EDO15716.1 - 0.024 14.5 0.2 8.6 6.3 0.0 2.7 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain ARPC4 PF05856.7 EDO15717.1 - 1.3e-71 239.4 4.8 1.4e-71 239.3 3.3 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FF PF01846.14 EDO15718.1 - 2e-33 114.1 28.7 6.7e-13 48.3 0.4 6.6 7 2 1 8 8 8 3 FF domain WW PF00397.21 EDO15718.1 - 4.3e-21 74.4 7.3 9.5e-11 41.3 1.1 2.7 2 0 0 2 2 2 2 WW domain PQQ PF01011.16 EDO15718.1 - 7.3e-05 22.0 0.1 0.039 13.4 0.0 2.5 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.1 EDO15718.1 - 0.00061 19.3 0.1 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain Toxin_57 PF15535.1 EDO15718.1 - 6.4 6.9 6.1 20 5.3 0.4 2.4 1 1 1 2 2 2 0 Putative toxin 57 ParBc PF02195.13 EDO15720.1 - 4e-14 52.4 0.0 4.7e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Ldh_1_C PF02866.13 EDO15721.1 - 6.4e-50 169.2 0.0 9.7e-50 168.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EDO15721.1 - 8.7e-44 148.7 0.1 1.6e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EDO15721.1 - 0.00069 18.4 0.0 0.001 17.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EDO15721.1 - 0.064 12.5 1.0 0.62 9.3 0.1 2.4 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase CbiG_N PF11760.3 EDO15721.1 - 0.15 11.7 0.7 1.2 8.8 0.2 2.2 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal Ank_4 PF13637.1 EDO15722.1 - 2e-21 75.9 1.7 3e-07 30.7 0.1 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO15722.1 - 8.5e-21 74.1 0.1 5.5e-09 36.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDO15722.1 - 6.3e-20 69.9 4.6 0.00059 19.5 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EDO15722.1 - 3.3e-13 49.4 2.1 5.7e-05 23.2 0.0 4.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO15722.1 - 7.6e-12 44.2 3.0 0.13 12.5 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat TUG-UBL1 PF11470.3 EDO15723.1 - 2.5e-20 72.1 0.1 9e-20 70.3 0.0 2.0 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EDO15723.1 - 6.7e-12 45.3 0.1 1.8e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain PPR_2 PF13041.1 EDO15724.1 - 0.0011 18.8 6.4 2.1 8.4 0.0 5.7 6 0 0 6 6 6 2 PPR repeat family TPR_19 PF14559.1 EDO15724.1 - 0.0015 18.8 1.1 10 6.5 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO15724.1 - 0.038 14.1 0.6 39 4.4 0.1 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Pyr_redox PF00070.22 EDO15724.1 - 0.2 12.0 0.6 4.6 7.7 0.1 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EF1G PF00647.14 EDO15725.1 - 1.6e-48 162.8 0.2 3.4e-48 161.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EDO15725.1 - 2.6e-10 40.1 1.0 1.4e-09 37.8 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EDO15725.1 - 6e-10 39.1 0.0 1.4e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDO15725.1 - 0.0002 21.1 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EDO15725.1 - 0.0027 17.8 0.0 0.0053 16.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EDO15725.1 - 0.0068 16.8 0.0 0.017 15.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Med3 PF11593.3 EDO15725.1 - 0.039 13.2 0.1 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RNase_HII PF01351.13 EDO15726.1 - 0.046 13.3 0.1 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease HII SUR7 PF06687.7 EDO15727.1 - 9.3e-24 84.1 19.4 1.4e-23 83.6 13.5 1.2 1 0 0 1 1 1 1 SUR7/PalI family OB_NTP_bind PF07717.11 EDO15728.1 - 7.2e-19 67.7 0.0 1.8e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDO15728.1 - 4.5e-18 65.1 2.2 4.5e-18 65.1 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDO15728.1 - 3.9e-11 42.6 0.0 3.9e-10 39.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO15728.1 - 1.2e-09 37.8 0.2 2.7e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO15728.1 - 2.5e-05 24.4 1.8 3.2e-05 24.0 0.2 1.9 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EDO15728.1 - 0.0012 18.4 0.0 0.0089 15.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 EDO15728.1 - 0.0013 18.2 0.0 0.0039 16.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EDO15728.1 - 0.004 17.4 0.3 0.014 15.7 0.2 1.9 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 EDO15728.1 - 0.0057 16.5 0.7 0.099 12.5 0.5 2.7 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EDO15728.1 - 0.0071 15.5 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EDO15728.1 - 0.013 15.0 0.9 4.7 6.5 0.0 2.6 3 0 0 3 3 3 0 AAA-like domain Flavi_DEAD PF07652.9 EDO15728.1 - 0.05 13.3 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain PhoH PF02562.11 EDO15728.1 - 0.052 12.7 0.0 0.18 11.0 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein T2SE PF00437.15 EDO15728.1 - 0.057 12.3 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 EDO15728.1 - 0.059 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDO15728.1 - 0.4 10.3 5.5 0.1 12.2 0.3 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_11 PF13086.1 EDO15728.1 - 2.4 7.6 8.5 0.4 10.2 0.1 2.8 2 1 1 3 3 2 0 AAA domain ArgJ PF01960.13 EDO15729.1 - 1.2e-143 478.1 7.3 1.4e-143 477.9 5.0 1.0 1 0 0 1 1 1 1 ArgJ family Cu-oxidase_2 PF07731.9 EDO15730.1 - 6.3e-43 145.5 5.4 1.5e-37 128.1 1.6 2.7 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EDO15730.1 - 1.3e-39 135.6 4.4 2.3e-37 128.3 0.7 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EDO15730.1 - 2.8e-39 133.4 9.5 1.7e-37 127.7 0.2 3.4 5 0 0 5 5 5 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EDO15730.1 - 0.0014 18.5 0.0 0.22 11.4 0.0 3.4 3 1 0 3 3 3 1 Cupredoxin-like domain RRM_5 PF13893.1 EDO15731.1 - 0.0024 17.7 0.0 0.0083 15.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO15731.1 - 0.02 14.5 0.0 0.068 12.8 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoIIID PF12116.3 EDO15732.1 - 0.13 12.1 3.2 0.31 10.9 2.2 1.7 1 0 0 1 1 1 0 Stage III sporulation protein D COX16 PF14138.1 EDO15732.1 - 0.14 12.3 0.4 0.14 12.3 0.3 2.1 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 SSXT PF05030.7 EDO15732.1 - 0.95 9.0 6.0 8.6 6.0 0.7 2.5 1 1 1 2 2 2 0 SSXT protein (N-terminal region) GAF_2 PF13185.1 EDO15733.1 - 2.5e-07 31.3 0.0 4.2e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EDO15733.1 - 0.0054 16.8 0.0 0.0062 16.6 0.0 1.4 1 1 0 1 1 1 1 GAF domain Swi3 PF07962.7 EDO15734.1 - 4.6e-26 90.2 0.1 7.2e-26 89.6 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 IR1-M PF12185.3 EDO15735.1 - 9.2 6.0 9.0 7.1 6.4 3.4 2.1 1 1 1 2 2 2 0 Nup358/RanBP2 E3 ligase domain Nucleoporin_FG PF13634.1 EDO15736.1 - 1.1e-53 180.3 336.8 5.2e-13 49.2 30.1 9.6 2 1 7 9 9 9 7 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 EDO15736.1 - 5.5e-47 159.1 0.0 1.3e-46 157.8 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin autopeptidase PWWP PF00855.12 EDO15737.1 - 3.5e-17 62.3 1.4 3.5e-17 62.3 1.0 2.7 2 2 0 2 2 2 1 PWWP domain LMBR1 PF04791.11 EDO15737.1 - 0.23 9.9 5.3 0.33 9.4 3.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein SRF-TF PF00319.13 EDO15738.1 - 2.5e-25 87.4 0.3 3.9e-25 86.8 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF605 PF04652.11 EDO15738.1 - 0.92 8.8 22.1 1.3 8.3 15.3 1.1 1 0 0 1 1 1 0 Vta1 like SRF-TF PF00319.13 EDO15739.1 - 6.3e-19 66.9 0.6 9e-19 66.4 0.4 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) ELH PF02323.10 EDO15739.1 - 0.028 13.5 0.0 0.033 13.3 0.0 1.1 1 0 0 1 1 1 0 Egg-laying hormone precursor DUF3793 PF12672.2 EDO15739.1 - 0.049 13.2 0.2 0.06 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Clat_adaptor_s PF01217.15 EDO15740.1 - 1.3e-49 167.6 3.9 1.4e-49 167.4 2.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Urb2 PF10441.4 EDO15743.1 - 3.6e-64 216.4 3.3 3.6e-64 216.4 2.3 2.6 3 0 0 3 3 3 1 Urb2/Npa2 family Chor_lyase PF04345.8 EDO15743.1 - 0.0063 15.9 0.8 0.37 10.2 0.0 3.1 3 0 0 3 3 3 1 Chorismate lyase CSTF2_hinge PF14327.1 EDO15743.1 - 0.012 15.6 0.3 0.057 13.4 0.2 2.2 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 SAM_2 PF07647.12 EDO15744.1 - 1.2e-09 37.8 0.2 5.7e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EDO15744.1 - 4.4e-05 23.5 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PDEase_I PF00233.14 EDO15745.1 - 1.4e-48 165.7 5.1 6.5e-48 163.5 3.6 2.0 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 EDO15745.1 - 0.074 13.0 0.1 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 HD domain BolA PF01722.13 EDO15746.1 - 1.6e-21 75.9 0.2 2.2e-21 75.5 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein BolA PF01722.13 EDO15747.1 - 2.6e-17 62.5 0.0 5.3e-17 61.5 0.0 1.5 2 0 0 2 2 2 1 BolA-like protein Mto2_bdg PF12808.2 EDO15748.1 - 3.6e-06 26.9 10.1 3.6e-06 26.9 7.0 3.5 4 0 0 4 4 4 1 Micro-tubular organiser Mto1 C-term Mto2-binding region DAGK_prokar PF01219.14 EDO15748.1 - 0.16 11.6 0.6 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Miro PF08477.8 EDO15749.1 - 1.3e-39 135.3 0.0 7.7e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EDO15749.1 - 1.1e-28 98.3 0.9 2e-28 97.4 0.6 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.7 EDO15749.1 - 1.5e-27 95.1 0.0 4.6e-27 93.5 0.0 1.9 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EDO15749.1 - 5.4e-21 74.6 0.0 2.8e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EDO15749.1 - 2.6e-10 40.2 0.0 0.00035 20.5 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 EDO15749.1 - 4.4e-09 34.9 0.8 0.00011 21.2 0.3 3.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EDO15749.1 - 4e-07 30.0 0.3 0.007 16.4 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDO15749.1 - 7.1e-07 28.5 1.4 0.00079 19.1 0.2 3.0 2 0 0 2 2 2 1 EF-hand domain Dynamin_N PF00350.18 EDO15749.1 - 4.4e-06 26.6 0.1 0.027 14.3 0.0 2.4 2 0 0 2 2 2 2 Dynamin family EF-hand_8 PF13833.1 EDO15749.1 - 7.9e-05 22.2 0.7 0.1 12.2 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EDO15749.1 - 0.00011 21.3 3.2 0.00084 18.5 0.8 2.8 2 0 0 2 2 2 1 EF hand AAA_10 PF12846.2 EDO15749.1 - 0.00017 21.1 0.0 0.53 9.6 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain AAA_29 PF13555.1 EDO15749.1 - 0.00017 21.0 0.0 0.38 10.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.1 EDO15749.1 - 0.00018 21.1 0.1 0.087 12.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDO15749.1 - 0.0005 20.2 0.0 0.097 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EDO15749.1 - 0.00056 19.6 0.1 0.19 11.4 0.4 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 EDO15749.1 - 0.00094 18.4 0.0 0.0042 16.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF258 PF03193.11 EDO15749.1 - 0.0011 18.1 0.0 0.0087 15.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EDO15749.1 - 0.0014 18.1 0.0 5.7 6.3 0.0 3.7 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EDO15749.1 - 0.0014 18.9 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Arch_ATPase PF01637.13 EDO15749.1 - 0.0022 17.7 0.0 0.4 10.3 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_23 PF13476.1 EDO15749.1 - 0.0038 17.5 0.2 0.99 9.6 0.4 2.8 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EDO15749.1 - 0.0051 16.8 0.2 0.86 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDO15749.1 - 0.0075 16.2 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EDO15749.1 - 0.0086 16.3 0.1 2.5 8.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EDO15749.1 - 0.011 15.9 0.0 2.1 8.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 EDO15749.1 - 0.017 14.6 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.13 EDO15749.1 - 0.032 13.2 0.0 0.31 10.0 0.0 2.1 2 0 0 2 2 2 0 Septin FeoB_N PF02421.13 EDO15749.1 - 0.067 12.4 0.2 5.5 6.2 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF815 PF05673.8 EDO15749.1 - 0.094 11.6 0.1 1.8 7.4 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 EDO15749.1 - 0.11 13.3 0.0 4.8 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 EDO15749.1 - 0.25 9.9 0.0 1.3 7.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain DLH PF01738.13 EDO15750.1 - 6.4e-21 74.6 0.0 8e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EDO15750.1 - 1.5e-06 28.0 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family STb_secrete PF09075.5 EDO15750.1 - 0.11 12.3 1.4 0.23 11.3 1.0 1.5 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory TRP PF06011.7 EDO15751.1 - 9.9e-157 521.9 35.6 9.9e-157 521.9 24.7 1.4 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EDO15751.1 - 5e-46 156.2 4.2 8.7e-46 155.4 2.9 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EDO15751.1 - 0.00011 22.4 0.2 0.00019 21.6 0.1 1.4 1 0 0 1 1 1 1 ML domain CH PF00307.26 EDO15752.1 - 2e-08 34.2 0.2 2.8e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Peroxin-22 PF12827.2 EDO15753.1 - 8.7e-29 99.6 0.0 1.1e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family Shadoo PF14999.1 EDO15753.1 - 0.66 9.8 3.8 1 9.2 2.6 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Rad1 PF02144.11 EDO15754.1 - 1.5e-70 237.0 1.4 2e-70 236.6 1.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ribosomal_L7Ae PF01248.21 EDO15755.1 - 3.3e-22 77.7 0.5 4.2e-22 77.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 EDO15755.1 - 0.003 17.5 0.4 0.0087 16.0 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1269) GDI PF00996.13 EDO15756.1 - 2.7e-59 200.6 0.0 3.7e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Kelch_4 PF13418.1 EDO15757.1 - 5.9e-11 41.9 11.0 0.0024 17.6 0.2 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EDO15757.1 - 6.5e-05 22.7 11.8 0.16 11.9 0.1 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.1 EDO15757.1 - 7.5e-05 22.7 9.1 1 9.6 0.5 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.10 EDO15757.1 - 0.0011 18.6 11.2 1 9.2 0.7 5.9 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.1 EDO15757.1 - 0.11 12.7 8.0 0.98 9.6 0.1 5.0 6 0 0 6 6 6 0 Galactose oxidase, central domain Kelch_1 PF01344.20 EDO15757.1 - 0.14 11.7 13.3 3.3 7.3 0.0 5.0 6 0 0 6 6 6 0 Kelch motif Calreticulin PF00262.13 EDO15758.1 - 1.1e-128 428.9 12.8 1.5e-128 428.5 8.9 1.1 1 0 0 1 1 1 1 Calreticulin family Alb1 PF09135.6 EDO15759.1 - 2.7e-30 105.2 10.3 2.7e-30 105.2 7.1 1.8 1 1 1 2 2 2 1 Alb1 ADH_N PF08240.7 EDO15760.1 - 7.6e-33 112.5 2.2 1.3e-32 111.7 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO15760.1 - 1e-23 83.2 0.0 1.8e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.22 EDO15760.1 - 0.0018 18.6 0.0 0.0043 17.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EDO15760.1 - 0.022 14.8 0.0 0.086 12.9 0.0 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EDO15760.1 - 0.034 14.4 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EDO15760.1 - 0.052 12.6 0.0 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ank_3 PF13606.1 EDO15760.1 - 0.082 13.1 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat Zn_clus PF00172.13 EDO15761.1 - 9.5e-09 35.0 13.1 1.7e-08 34.2 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EDO15762.1 - 5.2e-160 532.9 36.7 5.9e-160 532.7 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO15762.1 - 1e-28 100.1 37.0 5.4e-25 87.8 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Flocculin PF00624.13 EDO15763.1 - 1.5e-77 255.1 310.4 1.1e-12 47.5 11.0 88.5 76 13 14 90 90 90 22 Flocculin repeat Cofilin_ADF PF00241.15 EDO15764.1 - 4.6e-43 146.1 0.1 5.6e-43 145.8 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ABC_tran PF00005.22 EDO15765.1 - 0.0044 17.3 0.5 0.009 16.3 0.2 1.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EDO15765.1 - 0.058 12.6 0.9 0.068 12.3 0.6 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Phosphodiest PF01663.17 EDO15766.1 - 4.8e-12 45.8 0.2 7.3e-12 45.2 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EDO15766.1 - 0.012 15.0 3.3 0.029 13.7 1.9 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily Peptidase_M24 PF00557.19 EDO15767.1 - 1.2e-40 139.3 0.0 2e-40 138.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EDO15767.1 - 6.3e-13 49.3 0.0 1.1e-09 38.8 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain MFS_1 PF07690.11 EDO15768.1 - 8.5e-39 133.2 36.0 8.5e-39 133.2 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO15768.1 - 6.3e-08 31.6 36.9 2.8e-07 29.4 25.2 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter NADH-u_ox-rdase PF10785.4 EDO15768.1 - 0.028 14.6 0.0 0.028 14.6 0.0 2.7 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit AAA_2 PF07724.9 EDO15769.1 - 7.8e-47 159.3 0.1 9.1e-46 155.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EDO15769.1 - 6.6e-23 80.4 1.7 3.3e-22 78.1 1.2 2.4 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EDO15769.1 - 2.2e-22 79.6 3.2 9.2e-14 51.7 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO15769.1 - 5.6e-15 55.2 0.0 3.7e-08 33.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 EDO15769.1 - 7.9e-15 54.5 4.4 1.7e-09 37.4 0.7 3.2 2 0 0 2 2 2 2 Clp amino terminal domain Sigma54_activat PF00158.21 EDO15769.1 - 6.9e-10 38.6 0.1 2.5e-07 30.3 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 EDO15769.1 - 9.4e-10 38.7 12.0 8.3e-05 22.6 0.0 5.2 5 2 1 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 EDO15769.1 - 1.1e-08 35.2 0.1 0.0069 16.5 0.0 3.5 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EDO15769.1 - 1.6e-05 23.8 6.9 0.11 11.1 0.0 4.5 4 1 0 5 5 5 2 TIP49 C-terminus AAA_3 PF07726.6 EDO15769.1 - 0.00016 21.2 0.0 0.4 10.2 0.0 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 EDO15769.1 - 0.00023 21.0 0.0 0.0035 17.2 0.0 2.6 2 0 0 2 2 2 1 Torsin Zeta_toxin PF06414.7 EDO15769.1 - 0.0003 19.9 0.3 0.016 14.3 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 EDO15769.1 - 0.0007 19.2 0.0 0.53 10.0 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EDO15769.1 - 0.00077 19.1 0.1 1 9.0 0.0 3.1 3 0 0 3 3 2 2 NACHT domain Mg_chelatase PF01078.16 EDO15769.1 - 0.0011 18.1 0.0 0.52 9.4 0.0 3.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EDO15769.1 - 0.0072 16.2 1.1 0.26 11.1 0.0 3.4 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.12 EDO15769.1 - 0.011 15.1 0.0 1.8 7.9 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EDO15769.1 - 0.02 15.7 11.4 0.2 12.4 0.0 4.5 4 1 0 4 4 4 0 AAA domain AAA_10 PF12846.2 EDO15769.1 - 0.054 12.9 5.8 0.33 10.3 0.4 3.8 4 1 0 4 4 4 0 AAA-like domain PEPCK_ATP PF01293.15 EDO15769.1 - 0.07 11.6 0.0 0.15 10.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase RNA_helicase PF00910.17 EDO15769.1 - 0.071 13.2 0.0 18 5.5 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_18 PF13238.1 EDO15769.1 - 0.18 12.0 7.3 3.1 8.1 0.0 4.5 3 2 1 4 4 4 0 AAA domain ABC_tran PF00005.22 EDO15769.1 - 0.19 12.0 6.4 0.47 10.7 0.3 3.7 3 1 0 3 3 3 0 ABC transporter Arch_ATPase PF01637.13 EDO15769.1 - 0.83 9.3 16.3 0.91 9.1 0.0 4.9 5 2 1 6 6 6 0 Archaeal ATPase RRM_1 PF00076.17 EDO15770.1 - 2.7e-29 100.5 1.6 3.3e-15 55.4 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO15770.1 - 1.4e-21 76.0 0.5 6.8e-08 32.2 0.0 3.7 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO15770.1 - 4.6e-18 64.9 0.2 2.5e-07 30.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO15770.1 - 7.8e-08 31.9 0.2 0.0022 17.7 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Ribonuc_red_sm PF00268.16 EDO15771.1 - 6.5e-115 382.9 1.2 9e-115 382.4 0.9 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain STN1_2 PF09170.5 EDO15771.1 - 0.055 13.2 0.6 0.12 12.1 0.4 1.5 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 zf-Tim10_DDP PF02953.10 EDO15772.1 - 6.4e-19 67.0 2.1 8.8e-19 66.5 1.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Myb_DNA-bind_6 PF13921.1 EDO15772.1 - 0.073 13.1 0.2 0.66 10.1 0.0 2.1 1 1 1 2 2 2 0 Myb-like DNA-binding domain DUF4280 PF14107.1 EDO15772.1 - 0.092 13.0 1.3 0.11 12.8 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4280) DUF3398 PF11878.3 EDO15772.1 - 0.13 12.1 0.1 0.17 11.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3398) zf-UBR PF02207.15 EDO15773.1 - 1.1e-12 47.4 13.4 1.1e-12 47.4 9.3 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) tRNA-synt_1b PF00579.20 EDO15774.1 - 1.7e-77 260.4 0.0 2.2e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TFIIF_alpha PF05793.7 EDO15775.1 - 2.7e-09 35.9 5.0 2.7e-09 35.9 3.5 2.2 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF383 PF04063.9 EDO15776.1 - 3.7e-70 235.3 0.6 1.5e-69 233.3 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EDO15776.1 - 2.2e-24 84.7 0.1 7.1e-24 83.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 EDO15776.1 - 0.046 14.0 0.0 0.28 11.4 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats PapB PF03333.8 EDO15776.1 - 0.11 12.3 0.4 0.28 11.0 0.1 1.8 2 0 0 2 2 2 0 Adhesin biosynthesis transcription regulatory protein Rab5ip PF07019.7 EDO15777.1 - 3.2e-22 78.4 6.7 3.9e-22 78.1 4.6 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) EIID-AGA PF03613.9 EDO15777.1 - 0.43 9.4 2.4 0.66 8.8 1.5 1.3 1 1 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component PUF PF00806.14 EDO15778.1 - 9.4e-54 175.9 13.6 7.2e-09 34.6 0.0 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Abhydro_lipase PF04083.11 EDO15779.1 - 3.4e-15 55.1 0.0 7.5e-15 54.0 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EDO15779.1 - 1.1e-06 28.6 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO15779.1 - 9.8e-05 22.0 0.0 0.0004 20.0 0.0 2.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold NIF PF03031.13 EDO15780.1 - 1.8e-50 170.6 0.6 3.2e-50 169.8 0.4 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase FA_desaturase PF00487.19 EDO15781.1 - 9.6e-20 71.0 17.7 9.6e-20 71.0 12.2 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EDO15781.1 - 6.9e-14 51.4 0.0 1.6e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF342 PF03961.8 EDO15782.1 - 0.026 12.9 11.9 0.034 12.5 6.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) IFP_35_N PF07334.8 EDO15782.1 - 0.076 12.9 1.1 0.27 11.2 0.7 2.0 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF4515 PF14988.1 EDO15782.1 - 0.11 12.1 9.2 0.15 11.7 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Cornichon PF03311.9 EDO15783.1 - 2.6e-52 176.2 7.7 3e-52 176.1 5.3 1.0 1 0 0 1 1 1 1 Cornichon protein DUF2269 PF10027.4 EDO15783.1 - 0.28 10.9 2.5 0.18 11.5 0.5 1.6 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) Ribosomal_S18 PF01084.15 EDO15784.1 - 4e-16 58.6 0.0 7.3e-16 57.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 BCDHK_Adom3 PF10436.4 EDO15785.1 - 5.6e-26 91.0 0.9 8.6e-26 90.3 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EDO15785.1 - 3.4e-15 55.7 0.0 8.5e-15 54.4 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDO15785.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BAR_2 PF10455.4 EDO15786.1 - 1.3e-85 286.7 18.1 1.3e-85 286.7 12.5 3.0 3 1 0 3 3 3 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EDO15786.1 - 1e-10 41.5 7.2 4.7e-10 39.3 5.0 2.0 1 1 0 1 1 1 1 BAR domain DUF2891 PF11199.3 EDO15786.1 - 0.015 13.8 0.3 0.023 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) P22_AR_C PF10548.4 EDO15786.1 - 0.027 14.3 0.1 0.072 12.9 0.1 1.8 1 0 0 1 1 1 0 P22AR C-terminal domain HTH_WhiA PF02650.9 EDO15786.1 - 0.062 13.6 1.7 0.17 12.2 0.1 2.4 2 0 0 2 2 2 0 WhiA C-terminal HTH domain RNA_pol_Rpb1_5 PF04998.12 EDO15790.1 - 2e-99 332.3 0.1 6e-98 327.4 0.0 2.9 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EDO15790.1 - 8.4e-65 217.7 0.1 2.5e-64 216.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EDO15790.1 - 1.1e-41 142.1 2.8 8.3e-40 136.0 0.0 4.1 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EDO15790.1 - 9.7e-24 83.1 0.1 9.7e-24 83.1 0.0 3.5 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 EDO15790.1 - 8.6e-18 64.6 9.2 8.6e-18 64.6 6.4 4.8 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 SHS2_Rpb7-N PF03876.12 EDO15791.1 - 1.1e-13 51.0 0.0 2.4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 SWIRM PF04433.12 EDO15792.1 - 4.7e-13 49.0 0.0 9.6e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain UDP-g_GGTase PF06427.6 EDO15793.1 - 2.2e-08 33.6 0.1 8.8e-08 31.6 0.0 1.9 1 1 1 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase tRNA-synt_2c PF01411.14 EDO15794.1 - 5.6e-226 751.1 0.0 9e-226 750.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EDO15794.1 - 3.2e-19 68.5 0.1 7.9e-19 67.2 0.1 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EDO15794.1 - 5.1e-07 29.3 3.8 1.2e-06 28.0 2.6 1.7 1 0 0 1 1 1 1 DHHA1 domain Synaptobrevin PF00957.16 EDO15795.1 - 3.4e-32 109.9 0.5 3.8e-32 109.7 0.4 1.0 1 0 0 1 1 1 1 Synaptobrevin Hph PF13694.1 EDO15796.1 - 6.6e-46 156.7 23.1 6.6e-46 156.7 16.0 3.1 3 0 0 3 3 3 2 Sec63/Sec62 complex-interacting family FliJ PF02050.11 EDO15796.1 - 0.0012 18.9 3.2 0.0031 17.5 2.2 1.7 1 0 0 1 1 1 1 Flagellar FliJ protein Sec8_exocyst PF04048.9 EDO15796.1 - 0.19 11.3 11.0 2.6 7.6 0.1 3.3 2 2 1 3 3 3 0 Sec8 exocyst complex component specific domain HAD PF12710.2 EDO15797.1 - 1.7e-20 74.0 0.2 3.9e-20 72.8 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EDO15797.1 - 1.3e-16 60.3 0.8 2.3e-16 59.5 0.6 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDO15797.1 - 5.1e-13 49.9 0.7 3.5e-11 43.9 0.5 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO15797.1 - 5.6e-11 42.2 0.0 1.8e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDO15797.1 - 0.0014 18.2 0.2 0.014 14.9 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDO15797.1 - 0.092 12.9 0.3 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase LDB19 PF13002.2 EDO15798.1 - 4.3e-72 241.6 0.6 6.5e-72 241.0 0.4 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EDO15798.1 - 0.00011 22.0 2.5 0.00011 21.9 0.1 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Spo0M PF07070.6 EDO15798.1 - 0.01 15.2 0.3 0.088 12.1 0.0 2.3 2 0 0 2 2 2 1 SpoOM protein DUF2616 PF11077.3 EDO15798.1 - 0.044 13.2 1.7 2.3 7.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) PMT PF02366.13 EDO15799.1 - 5.3e-87 291.2 21.3 5.3e-87 291.2 14.8 2.5 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDO15799.1 - 4.7e-29 101.2 1.7 8.7e-29 100.4 1.2 1.4 1 0 0 1 1 1 1 MIR domain Nucleoside_tran PF01733.13 EDO15800.1 - 7.1e-55 186.3 19.8 1.5e-37 129.4 3.9 2.3 1 1 1 2 2 2 2 Nucleoside transporter Exo_endo_phos PF03372.18 EDO15801.1 - 3.9e-26 92.5 0.2 5.9e-26 91.9 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EDO15801.1 - 1.6e-14 53.0 14.6 3.3e-09 36.1 4.4 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO15801.1 - 3.6e-10 39.4 11.9 7.1e-09 35.3 4.0 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EDO15801.1 - 5.4e-09 34.8 14.4 0.016 15.1 0.2 6.1 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EDO15801.1 - 0.0054 16.7 25.2 0.14 12.4 0.2 6.2 5 1 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EDO15801.1 - 0.081 13.0 15.7 0.63 10.2 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich repeat RCC1 PF00415.13 EDO15802.1 - 7.1e-23 80.5 17.4 8.2e-05 22.7 1.4 6.4 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDO15802.1 - 1.9e-19 68.7 18.7 4.6e-10 38.8 2.1 5.3 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PAN_3 PF08277.7 EDO15802.1 - 0.03 13.9 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 PAN-like domain DUF4213 PF13938.1 EDO15802.1 - 0.066 13.3 0.6 37 4.5 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4213) tRNA-synt_1b PF00579.20 EDO15803.1 - 0.017 14.2 3.6 0.023 13.8 2.5 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) SNF2_N PF00176.18 EDO15804.1 - 4.9e-71 238.9 0.6 9.8e-71 237.9 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO15804.1 - 3.8e-16 58.7 0.0 1.2e-14 53.9 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDO15804.1 - 0.0024 18.0 0.0 0.029 14.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain Ras_bdg_2 PF14847.1 EDO15804.1 - 0.085 12.7 6.1 0.26 11.2 0.1 4.0 3 1 0 3 3 3 0 Ras-binding domain of Byr2 GSH_synth_ATP PF03917.12 EDO15805.1 - 1.8e-122 408.5 0.0 2.1e-122 408.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EDO15805.1 - 2.5e-38 130.3 0.0 4.4e-38 129.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF3635 PF12330.3 EDO15806.1 - 2.6 8.1 5.1 0.77 9.8 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3635) Pkinase PF00069.20 EDO15807.1 - 1.6e-63 214.3 0.0 1.6e-63 214.3 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15807.1 - 5.7e-25 87.8 0.0 1e-24 87.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO15807.1 - 2.3e-08 33.3 0.0 4.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.1 EDO15807.1 - 0.0014 19.0 0.0 0.46 10.8 0.0 2.9 2 0 0 2 2 2 1 PAS domain Kdo PF06293.9 EDO15807.1 - 0.0023 17.0 0.0 0.0078 15.2 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO15807.1 - 0.016 14.9 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family HEAT PF02985.17 EDO15808.1 - 1.9e-38 127.0 20.4 0.0035 17.2 0.0 12.8 13 0 0 13 13 13 8 HEAT repeat HEAT_2 PF13646.1 EDO15808.1 - 3.4e-31 107.3 0.3 9.6e-08 32.2 0.0 7.1 3 1 5 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.2 EDO15808.1 - 2.2e-12 47.1 5.0 0.035 14.4 0.0 7.6 4 2 4 8 8 8 5 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EDO15808.1 - 1.7e-09 37.9 9.8 0.5 10.9 0.0 8.1 7 2 2 9 9 9 1 HEAT-like repeat API5 PF05918.6 EDO15808.1 - 0.0056 15.2 0.6 0.34 9.3 0.0 3.1 2 2 2 4 4 4 1 Apoptosis inhibitory protein 5 (API5) Arm PF00514.18 EDO15808.1 - 0.016 15.0 0.3 3.5 7.5 0.1 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF2454 PF10521.4 EDO15808.1 - 0.018 14.0 7.2 0.2 10.6 0.1 4.7 2 1 1 5 5 5 0 Protein of unknown function (DUF2454) RIX1 PF08167.7 EDO15808.1 - 0.025 14.2 8.4 3.2 7.4 0.5 4.5 3 3 0 4 4 4 0 rRNA processing/ribosome biogenesis Trp_Tyr_perm PF03222.8 EDO15808.1 - 0.086 11.6 0.0 0.18 10.5 0.0 1.5 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Ipi1_N PF12333.3 EDO15808.1 - 0.35 10.8 2.0 21 5.1 0.1 4.1 4 1 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation HhH-GPD PF00730.20 EDO15809.1 - 2.4e-22 79.2 0.0 4.3e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EDO15809.1 - 7.4e-06 25.3 0.0 2.1e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRM_1 PF00076.17 EDO15810.1 - 4.7e-18 64.5 4.9 8.1e-16 57.4 0.1 3.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO15810.1 - 1.5e-14 53.6 1.1 2.8e-12 46.4 0.0 3.3 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO15810.1 - 8.5e-12 44.7 0.7 7.7e-08 32.0 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EDO15810.1 - 0.025 14.0 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein family 7 Nup35_RRM_2 PF14605.1 EDO15810.1 - 0.034 13.9 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Ribosomal_S19 PF00203.16 EDO15811.1 - 6.2e-33 112.2 0.1 8.8e-33 111.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DUF3619 PF12279.3 EDO15811.1 - 0.15 12.1 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Ribosomal_60s PF00428.14 EDO15812.1 - 1.1e-23 83.3 16.2 1.4e-23 83.0 11.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein KfrA_N PF11740.3 EDO15812.1 - 0.78 10.2 8.1 1.4 9.3 5.6 1.4 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Ydc2-catalyt PF09159.5 EDO15813.1 - 1.4e-51 175.6 0.0 1.6e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Borrelia_P83 PF05262.6 EDO15814.1 - 0.04 12.2 15.4 0.046 11.9 10.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.4 EDO15814.1 - 0.77 7.9 38.3 1 7.5 26.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SOBP PF15279.1 EDO15814.1 - 0.97 9.7 22.2 1.3 9.3 15.4 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein U79_P34 PF03064.11 EDO15814.1 - 2.1 7.7 12.2 3.1 7.2 8.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC27 PF09507.5 EDO15814.1 - 3.3 6.8 36.9 4.5 6.3 25.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1421 PF07223.6 EDO15814.1 - 4.9 6.8 45.0 6.8 6.3 31.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Fungal_trans PF04082.13 EDO15815.1 - 1.1e-24 86.7 13.9 1.3e-24 86.5 3.8 2.6 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO15815.1 - 0.0005 19.9 10.5 0.00067 19.5 6.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Npa1 PF11707.3 EDO15816.1 - 5e-104 347.8 1.7 5e-104 347.8 1.2 3.2 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal Mt_ATP-synt_D PF05873.7 EDO15817.1 - 2e-13 50.3 1.1 2.5e-13 49.9 0.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF4325 PF14213.1 EDO15817.1 - 0.0038 16.8 0.1 0.026 14.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4325) EzrA PF06160.7 EDO15817.1 - 0.02 13.0 4.2 0.091 10.9 2.7 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF2408 PF10303.4 EDO15817.1 - 0.2 11.7 1.4 0.43 10.6 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) OmpH PF03938.9 EDO15817.1 - 0.38 10.6 4.2 0.88 9.4 2.9 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) AAA_12 PF13087.1 EDO15818.1 - 7.9e-58 195.1 0.0 1.6e-57 194.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDO15818.1 - 1.3e-53 182.0 0.0 2e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO15818.1 - 5.6e-14 51.6 0.0 1.3e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EDO15818.1 - 1.2e-10 41.3 0.0 2.3e-07 30.5 0.0 2.5 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EDO15818.1 - 6.7e-07 29.0 0.1 0.063 12.7 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EDO15818.1 - 1.3e-06 27.9 0.1 6.1e-06 25.7 0.0 2.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EDO15818.1 - 2e-05 23.9 0.1 0.00013 21.2 0.0 2.3 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.1 EDO15818.1 - 3e-05 24.1 0.0 0.00094 19.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 EDO15818.1 - 9.1e-05 22.0 0.1 0.00058 19.4 0.0 2.2 1 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_RecD PF05127.9 EDO15818.1 - 0.00015 21.4 0.0 0.002 17.7 0.0 2.5 2 0 0 2 2 2 1 Helicase ResIII PF04851.10 EDO15818.1 - 0.00021 21.1 0.0 0.00074 19.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Zot PF05707.7 EDO15818.1 - 0.00052 19.5 0.0 0.0012 18.3 0.0 1.6 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) DUF2075 PF09848.4 EDO15818.1 - 0.0023 16.9 0.1 0.02 13.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 EDO15818.1 - 0.0025 16.8 0.0 0.19 10.6 0.0 2.3 2 0 0 2 2 2 1 PIF1-like helicase AAA_16 PF13191.1 EDO15818.1 - 0.0042 17.0 0.0 0.086 12.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EDO15818.1 - 0.0045 16.4 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDO15818.1 - 0.0054 16.1 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EDO15818.1 - 0.0087 15.9 0.2 0.89 9.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EDO15818.1 - 0.0092 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 EDO15818.1 - 0.011 15.9 0.0 0.13 12.4 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.4 EDO15818.1 - 0.017 13.7 0.0 0.032 12.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EDO15818.1 - 0.034 13.5 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF853 PF05872.7 EDO15818.1 - 0.037 12.4 0.0 0.068 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) SLA_LP_auto_ag PF05889.8 EDO15818.1 - 0.051 12.0 0.1 0.11 10.9 0.0 1.5 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) UPF0262 PF06793.7 EDO15818.1 - 0.055 13.1 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0262) DUF258 PF03193.11 EDO15818.1 - 0.08 12.1 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ArgK PF03308.11 EDO15818.1 - 0.083 11.6 0.2 0.26 10.0 0.0 1.8 2 0 0 2 2 2 0 ArgK protein AAA_5 PF07728.9 EDO15818.1 - 0.1 12.3 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EDO15818.1 - 0.28 12.0 3.1 0.93 10.3 1.2 2.6 2 1 0 2 2 2 0 AAA domain WD40 PF00400.27 EDO15819.1 - 1.1e-16 59.9 0.3 4.4e-05 23.2 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF1748 PF08520.5 EDO15820.1 - 3.5e-24 84.2 0.2 4.1e-24 83.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Apc15p PF05841.6 EDO15821.1 - 1.1e-29 103.7 0.0 1.1e-29 103.7 0.0 2.5 2 1 0 2 2 2 1 Apc15p protein DSPc PF00782.15 EDO15822.1 - 2.2e-24 85.5 1.7 1.9e-23 82.5 0.4 2.4 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EDO15822.1 - 0.0027 17.7 0.0 0.0069 16.4 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EDO15822.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.9 EDO15822.1 - 0.022 14.8 0.4 0.085 12.9 0.3 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PPTA PF01239.17 EDO15823.1 - 3.2e-37 124.3 18.7 7.5e-08 31.4 0.0 6.0 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat WD40 PF00400.27 EDO15824.1 - 6.6e-33 111.4 1.5 3.9e-09 36.0 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat CRT10 PF08728.5 EDO15824.1 - 0.00067 17.7 0.1 0.00067 17.7 0.1 1.8 1 1 1 2 2 2 1 CRT10 Nucleoporin_N PF08801.6 EDO15824.1 - 0.00093 18.0 3.2 4.5 5.9 0.0 4.2 1 1 2 4 4 4 3 Nup133 N terminal like Nup160 PF11715.3 EDO15824.1 - 0.0011 17.2 0.0 0.028 12.5 0.0 2.3 1 1 0 2 2 2 1 Nucleoporin Nup120/160 MraZ PF02381.13 EDO15824.1 - 0.013 15.2 0.1 12 5.7 0.0 3.5 4 0 0 4 4 4 0 MraZ protein AlaDh_PNT_N PF05222.10 EDO15825.1 - 6e-29 100.7 0.0 8.7e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EDO15825.1 - 1.2e-18 67.2 0.0 1.6e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TPR_2 PF07719.12 EDO15826.1 - 9.9e-32 106.2 3.9 0.00076 19.2 0.0 9.7 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_1 PF00515.23 EDO15826.1 - 2.6e-31 105.9 10.5 0.00015 21.1 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 EDO15826.1 - 7.3e-30 102.4 7.4 5.6e-09 35.5 0.0 7.0 6 1 0 6 6 6 4 TPR repeat Apc3 PF12895.2 EDO15826.1 - 1.1e-24 86.3 15.0 2.4e-22 78.8 0.1 4.9 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EDO15826.1 - 1.1e-18 67.3 1.0 0.00023 21.4 0.3 7.1 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO15826.1 - 2.9e-18 64.1 13.7 0.0012 18.4 0.0 8.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDO15826.1 - 3.1e-17 62.2 10.3 3e-05 23.8 0.3 7.4 5 3 1 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO15826.1 - 3.1e-15 55.2 0.0 0.0079 16.7 0.0 8.6 5 2 4 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDO15826.1 - 2.9e-14 51.9 1.9 0.15 12.3 0.0 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDO15826.1 - 4.1e-14 51.1 1.3 0.00017 21.1 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO15826.1 - 2.2e-13 50.4 0.0 0.05 14.2 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 EDO15826.1 - 3.1e-05 23.7 0.0 0.72 9.8 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDO15826.1 - 8.5e-05 22.3 0.0 0.035 13.9 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO15826.1 - 0.0002 21.5 11.7 27 5.4 0.0 7.9 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_21 PF09976.4 EDO15826.1 - 0.0013 18.6 0.6 1.8 8.5 0.0 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 EDO15826.1 - 0.0035 16.7 0.2 0.086 12.2 0.1 2.9 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_3 PF07720.7 EDO15826.1 - 0.0094 15.7 4.0 3.2 7.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2127 PF09900.4 EDO15826.1 - 0.038 14.0 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) Fis1_TPR_C PF14853.1 EDO15826.1 - 0.07 13.0 4.6 60 3.6 0.0 4.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Foie-gras_1 PF11817.3 EDO15826.1 - 0.088 12.2 2.5 0.47 9.8 0.1 3.2 4 0 0 4 4 2 0 Foie gras liver health family 1 ADK PF00406.17 EDO15828.1 - 2.5e-47 160.5 0.0 3.4e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EDO15828.1 - 8.1e-10 39.1 0.0 1.3e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO15828.1 - 2e-08 34.1 0.0 3.8e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO15828.1 - 7.4e-07 30.0 0.0 1.2e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EDO15828.1 - 4.9e-05 22.7 0.2 0.052 12.9 0.0 2.2 1 1 1 2 2 2 2 Thymidylate kinase SRP54 PF00448.17 EDO15828.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EDO15828.1 - 0.028 13.4 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin adh_short PF00106.20 EDO15829.1 - 2.6e-30 105.5 0.1 3.5e-30 105.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO15829.1 - 1.3e-13 51.3 0.3 1.5e-13 51.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO15829.1 - 1.5e-12 47.5 0.2 2e-12 47.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDO15829.1 - 5.1e-05 22.8 1.1 0.00037 19.9 0.8 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EDO15829.1 - 0.0012 17.7 0.7 0.0027 16.6 0.4 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EDO15829.1 - 0.0034 17.4 0.2 0.0059 16.6 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding DUF2150 PF09920.4 EDO15829.1 - 0.078 12.5 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) AMPKBI PF04739.10 EDO15830.1 - 0.019 14.8 3.4 0.69 9.8 2.3 2.5 1 1 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Sugar_tr PF00083.19 EDO15832.1 - 2.8e-161 537.0 36.6 3.2e-161 536.8 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO15832.1 - 2.1e-27 95.8 38.7 1.1e-26 93.3 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EDO15832.1 - 0.0031 15.7 3.2 0.0031 15.7 2.2 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector LMF1 PF06762.9 EDO15832.1 - 0.064 12.0 0.2 0.11 11.2 0.2 1.4 1 0 0 1 1 1 0 Lipase maturation factor Herpes_US9 PF06072.6 EDO15832.1 - 1.4 8.7 8.2 2.5 7.9 0.0 4.0 2 1 1 3 3 3 0 Alphaherpesvirus tegument protein US9 Epimerase PF01370.16 EDO15833.1 - 2.7e-18 66.2 0.0 3.6e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDO15833.1 - 6.7e-13 47.9 0.2 9.2e-13 47.5 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EDO15833.1 - 1.7e-10 40.2 0.0 3.5e-10 39.2 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EDO15833.1 - 7e-10 39.1 0.5 1.2e-09 38.4 0.4 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EDO15833.1 - 4e-07 30.1 0.0 6.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EDO15833.1 - 3.7e-06 26.0 0.2 5.9e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EDO15833.1 - 2.2e-05 24.1 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EDO15833.1 - 0.00066 19.0 0.1 0.0056 15.9 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.12 EDO15833.1 - 0.0016 18.7 0.4 0.0092 16.3 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EDO15833.1 - 0.035 14.2 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 EDO15833.1 - 0.047 12.5 0.0 0.091 11.6 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Mannosyl_trans3 PF11051.3 EDO15834.1 - 1.4e-64 218.0 2.5 2.3e-64 217.3 1.7 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative ADH_N PF08240.7 EDO15835.1 - 1.9e-25 88.7 4.4 3.2e-25 87.9 3.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO15835.1 - 1.4e-12 47.2 0.0 2.5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDO15835.1 - 2.9e-06 26.5 0.1 5.9e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF364 PF04016.7 EDO15835.1 - 0.012 14.8 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF364) MFS_1 PF07690.11 EDO15836.1 - 4.3e-37 127.6 33.7 4.3e-37 127.6 23.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDO15836.1 - 0.00044 18.5 4.5 0.00073 17.8 3.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EDO15836.1 - 0.005 14.9 9.6 0.034 12.2 3.9 3.0 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Metalloenzyme PF01676.13 EDO15839.1 - 0.0055 16.1 2.9 2.1 7.6 0.0 2.9 1 1 2 3 3 3 2 Metalloenzyme superfamily DERM PF14704.1 EDO15839.1 - 0.0079 16.1 0.2 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Dermatopontin DUF2974 PF11187.3 EDO15839.1 - 0.017 14.5 0.5 0.069 12.4 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2974) DUF2141 PF09912.4 EDO15839.1 - 0.091 12.4 0.3 0.21 11.2 0.1 1.7 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2141) Fae PF08714.6 EDO15839.1 - 0.24 11.1 2.9 2.5 7.7 0.2 2.8 1 1 2 3 3 3 0 Formaldehyde-activating enzyme (Fae) CHAP PF05257.11 EDO15839.1 - 7.8 6.1 10.7 15 5.2 0.8 3.0 1 1 1 2 2 2 0 CHAP domain Flocculin PF00624.13 EDO15840.1 - 1.1e-85 281.2 297.3 2.9e-12 46.1 7.1 181.3 180 1 0 180 180 180 20 Flocculin repeat Gly_radical PF01228.16 EDO15840.1 - 1.7e-45 153.6 34.6 3.4e+02 1.6 0.0 62.6 8 6 52 97 97 97 0 Glycine radical IFN-gamma PF00714.12 EDO15840.1 - 5.9 6.7 0.0 49 3.7 0.0 2.7 1 0 0 1 1 1 0 Interferon gamma Hexokinase_2 PF03727.11 EDO15841.1 - 2.3e-93 311.9 0.0 3e-93 311.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EDO15841.1 - 3.4e-80 268.2 0.0 4.4e-80 267.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 EDO15841.1 - 0.0016 17.8 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF2294 PF10057.4 EDO15841.1 - 0.16 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2294) SAC3_GANP PF03399.11 EDO15842.1 - 4.9e-28 98.0 3.8 4.9e-28 98.0 2.6 1.4 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EDO15842.1 - 2.8e-20 72.5 0.8 4.8e-20 71.7 0.5 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Ppx-GppA PF02541.11 EDO15843.1 - 2.2e-76 256.8 0.0 2.9e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Glyco_hydro_42 PF02449.10 EDO15844.1 - 1.5 7.8 9.5 0.27 10.2 3.7 1.8 2 0 0 2 2 2 0 Beta-galactosidase Adap_comp_sub PF00928.16 EDO15845.1 - 5.4e-09 35.5 0.7 8.1e-09 34.9 0.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDO15845.1 - 6.4e-08 32.4 2.1 1.1e-07 31.6 1.3 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain DUF4575 PF15143.1 EDO15845.1 - 0.047 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4575) tRNA-synt_1c PF00749.16 EDO15846.1 - 2.5e-115 384.4 0.1 3.3e-115 384.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EDO15846.1 - 6.6e-41 139.8 0.4 1.6e-40 138.5 0.2 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EDO15846.1 - 1.5e-05 25.3 0.0 4.4e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDO15846.1 - 6.5e-05 22.8 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDO15846.1 - 0.00016 21.4 0.0 0.00044 20.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF155 PF02582.9 EDO15847.1 - 2.9e-59 199.8 0.6 5.2e-59 199.0 0.4 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Plus-3 PF03126.13 EDO15848.1 - 1.7e-35 121.3 0.2 5.2e-35 119.7 0.1 1.9 1 0 0 1 1 1 1 Plus-3 domain Ank PF00023.25 EDO15849.1 - 2.4e-11 42.8 0.0 0.00053 19.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EDO15849.1 - 8.2e-09 35.4 0.0 6.1e-06 26.3 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO15849.1 - 1.7e-08 34.6 0.0 6.6e-08 32.7 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EDO15849.1 - 6.2e-07 29.0 0.0 0.00073 19.5 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EDO15849.1 - 3.2e-06 27.4 0.2 0.00018 21.9 0.0 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) CBFB_NFYA PF02045.10 EDO15850.1 - 1.1e-27 96.3 8.5 1.1e-27 96.3 5.9 1.8 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Dicty_REP PF05086.7 EDO15850.1 - 0.13 9.9 7.3 0.13 9.9 5.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.3 EDO15850.1 - 1.2 8.8 13.2 2.6 7.8 9.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ABC2_membrane_3 PF12698.2 EDO15850.1 - 4.8 6.1 9.8 6.6 5.6 6.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein GIDA PF01134.17 EDO15851.1 - 4.3e-155 516.4 0.0 5.3e-155 516.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EDO15851.1 - 6.7e-19 67.7 0.0 1.7e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EDO15851.1 - 1.4e-08 34.8 0.1 3.4e-08 33.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EDO15851.1 - 3.4e-06 26.4 1.5 5.9e-06 25.6 1.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EDO15851.1 - 1.9e-05 23.7 1.3 0.038 12.9 1.1 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDO15851.1 - 0.00039 20.7 0.9 0.001 19.4 0.6 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDO15851.1 - 0.00081 18.3 2.9 0.0016 17.3 2.0 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EDO15851.1 - 0.045 12.2 2.4 0.33 9.3 1.0 2.4 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 EDO15851.1 - 0.046 13.9 0.1 0.099 12.9 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EDO15851.1 - 0.15 11.5 0.7 0.3 10.6 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SAPS PF04499.10 EDO15852.1 - 4.5e-149 497.1 22.4 4.5e-149 497.1 15.5 2.8 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein DUF4441 PF14536.1 EDO15853.1 - 2 8.4 12.3 0.072 13.0 1.2 3.2 2 1 0 3 3 3 0 Domain of unknown function (DUF4441) DUF3892 PF13031.1 EDO15853.1 - 6.2 7.3 9.1 0.96 9.9 0.7 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3892) MCM PF00493.18 EDO15855.1 - 1.1e-142 474.6 0.2 1.6e-142 474.1 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EDO15855.1 - 3.8e-21 75.8 1.0 3.8e-21 75.8 0.7 2.3 2 1 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EDO15855.1 - 2.9e-06 27.0 0.0 1e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EDO15855.1 - 6.5e-06 25.4 0.0 0.0011 18.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDO15855.1 - 0.00068 19.2 0.0 0.0028 17.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EDO15855.1 - 0.021 14.2 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Imm19 PF15567.1 EDO15855.1 - 0.11 12.5 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 19 LSM PF01423.17 EDO15856.1 - 1.9e-18 65.7 0.8 2.5e-18 65.3 0.6 1.1 1 0 0 1 1 1 1 LSM domain Helicase_C PF00271.26 EDO15857.1 - 4.7e-24 84.0 0.0 1e-11 44.4 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EDO15857.1 - 1.8e-16 60.0 0.1 4.5e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3334 PF11813.3 EDO15857.1 - 0.007 15.9 2.3 0.015 14.8 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3334) DnaI_N PF07319.6 EDO15857.1 - 0.077 13.2 4.7 0.7 10.1 0.3 3.3 2 2 0 2 2 2 0 Primosomal protein DnaI N-terminus Hydrolase_3 PF08282.7 EDO15857.1 - 0.56 9.7 8.2 0.16 11.4 2.8 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase GAGA_bind PF06217.7 EDO15857.1 - 4.1 7.2 8.6 1.9 8.3 0.4 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family CPSF73-100_C PF11718.3 EDO15858.1 - 1.4e-65 220.7 5.3 1.4e-65 220.7 3.7 1.7 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EDO15858.1 - 3.2e-33 114.3 1.3 1.2e-32 112.4 0.0 2.5 3 0 0 3 3 3 1 Beta-Casp domain Lactamase_B PF00753.22 EDO15858.1 - 5.7e-17 62.0 0.5 9.3e-17 61.3 0.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDO15858.1 - 1.6e-13 50.6 1.4 8.7e-13 48.2 0.2 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EDO15858.1 - 3.5e-10 39.5 0.0 7e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EDO15858.1 - 9.9e-07 28.5 0.1 5.2e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Zn_clus PF00172.13 EDO15859.1 - 1.8e-06 27.7 10.1 4.7e-06 26.4 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_16 PF10294.4 EDO15860.1 - 2.1e-12 46.8 0.0 1e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EDO15860.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDO15860.1 - 0.087 11.9 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Glyco_hydro_18 PF00704.23 EDO15861.1 - 1.2e-23 84.1 3.1 3.1e-23 82.7 2.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.8 EDO15861.1 - 0.00013 21.6 9.4 0.00013 21.6 6.5 4.1 3 2 0 3 3 3 1 Carbohydrate binding domain (family 19) GTP_EFTU PF00009.22 EDO15862.1 - 6.1e-51 172.5 0.2 1.4e-50 171.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EDO15862.1 - 1.4e-34 118.1 8.9 3.6e-34 116.8 6.2 1.7 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EDO15862.1 - 7.7e-18 64.1 0.0 2e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDO15862.1 - 5.8e-05 23.1 1.1 0.0015 18.6 0.8 2.9 1 1 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EDO15862.1 - 0.0005 19.3 0.3 0.0018 17.5 0.1 2.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDO15862.1 - 0.0022 17.4 1.6 0.0032 16.8 0.0 2.0 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EDO15862.1 - 0.0082 16.6 0.0 0.023 15.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein SASP PF00269.15 EDO15862.1 - 0.02 14.7 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type DUSP PF06337.7 EDO15862.1 - 0.025 14.9 2.3 0.031 14.6 0.2 2.2 2 0 0 2 2 2 0 DUSP domain EFG_II PF14492.1 EDO15862.1 - 0.075 12.8 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 Elongation Factor G, domain II DUF244 PF03112.9 EDO15862.1 - 0.2 11.1 6.9 1.5 8.3 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF Ras PF00071.17 EDO15863.1 - 4e-50 169.3 0.0 5e-50 169.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO15863.1 - 8.1e-17 61.8 0.0 1.8e-16 60.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDO15863.1 - 4.7e-11 42.2 0.0 6.4e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EDO15863.1 - 0.0011 19.1 0.1 0.0063 16.6 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EDO15863.1 - 0.0027 16.8 0.0 0.0039 16.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 EDO15863.1 - 0.027 13.7 0.1 0.048 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EDO15863.1 - 0.038 14.1 0.1 0.19 11.8 0.1 2.0 1 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 EDO15863.1 - 0.055 12.1 2.6 1.1 7.8 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit SRPRB PF09439.5 EDO15863.1 - 0.056 12.6 0.0 0.098 11.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 EDO15863.1 - 0.067 12.8 0.3 0.13 11.9 0.1 1.5 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EDO15863.1 - 0.071 12.9 0.4 0.15 11.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EDO15863.1 - 0.083 12.0 0.2 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 KaiC ATP_sub_h PF10775.4 EDO15864.1 - 2.5e-24 84.7 1.2 3.8e-24 84.1 0.1 1.7 2 0 0 2 2 2 1 ATP synthase complex subunit h Hormone_3 PF00159.13 EDO15864.1 - 0.049 13.6 1.1 0.064 13.2 0.1 1.7 2 0 0 2 2 2 0 Pancreatic hormone peptide DUF1515 PF07439.6 EDO15864.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) zf-U1 PF06220.7 EDO15865.1 - 4e-18 64.6 6.8 6.9e-18 63.9 4.7 1.4 1 0 0 1 1 1 1 U1 zinc finger LUC7 PF03194.10 EDO15865.1 - 0.025 14.1 0.7 0.037 13.5 0.5 1.3 1 0 0 1 1 1 0 LUC7 N_terminus zf-C2H2_jaz PF12171.3 EDO15865.1 - 0.92 9.7 7.2 4.6 7.5 5.0 2.1 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding GTP_EFTU PF00009.22 EDO15866.1 - 5.6e-61 205.2 0.4 7.6e-61 204.8 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDO15866.1 - 1.1e-28 99.3 0.0 3.1e-28 97.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDO15866.1 - 1.8e-20 72.7 2.1 1.8e-20 72.7 1.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO15866.1 - 1.9e-05 24.5 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EDO15866.1 - 0.00036 20.1 0.4 0.001 18.6 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EDO15866.1 - 0.00051 20.5 0.2 0.0015 18.9 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 EDO15866.1 - 0.058 12.8 0.2 6.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DisA_N PF02457.11 EDO15866.1 - 0.088 11.9 0.1 0.28 10.3 0.0 1.9 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding CbiA PF01656.18 EDO15866.1 - 0.21 10.9 2.4 6.3 6.1 0.0 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain G_glu_transpept PF01019.16 EDO15867.1 - 5.3e-133 444.1 0.0 6.5e-133 443.8 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF1708 PF08101.6 EDO15868.1 - 4.6e-120 401.2 10.9 1.3e-119 399.8 7.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) INO80_Ies4 PF08193.6 EDO15869.1 - 0.0038 17.1 4.3 0.0038 17.1 3.0 1.4 1 1 0 1 1 1 1 INO80 complex subunit Ies4 NARP1 PF12569.3 EDO15869.1 - 1.3 7.7 12.0 1.3 7.7 8.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SAPS PF04499.10 EDO15869.1 - 1.9 7.0 8.7 2.2 6.7 6.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Cellulase PF00150.13 EDO15870.1 - 3e-11 43.0 0.3 3e-11 43.0 0.2 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) SNF2_N PF00176.18 EDO15871.1 - 2.1e-67 227.0 0.1 2.1e-67 227.0 0.0 2.7 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO15871.1 - 5.2e-14 51.8 0.1 1.1e-12 47.5 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EDO15871.1 - 2.8e-05 23.7 3.8 5.8e-05 22.7 2.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDO15871.1 - 0.00024 21.0 1.1 0.00067 19.6 0.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO15871.1 - 0.00063 19.5 4.5 0.0013 18.5 3.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDO15871.1 - 0.0017 18.0 0.9 0.0039 16.8 0.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO15871.1 - 0.0031 17.1 4.0 0.0068 16.0 2.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO15871.1 - 0.0032 17.1 1.4 0.0087 15.7 0.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EDO15871.1 - 0.24 10.9 0.6 0.66 9.5 0.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EDO15871.1 - 2.1 8.2 4.5 8.3 6.3 3.1 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING CBM_21 PF03370.8 EDO15872.1 - 2.9e-29 101.3 4.1 2.9e-29 101.3 2.9 2.7 2 1 0 2 2 2 1 Putative phosphatase regulatory subunit EXS PF03124.9 EDO15873.1 - 8.6e-90 301.2 24.9 1.3e-89 300.6 17.2 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EDO15873.1 - 4.8e-35 121.6 8.8 1.2e-21 77.6 1.3 2.5 1 1 1 2 2 2 2 SPX domain E1-E2_ATPase PF00122.15 EDO15874.1 - 2.4e-32 111.8 0.1 5e-32 110.7 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDO15874.1 - 1.1e-13 52.0 0.1 2.2e-12 47.8 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDO15874.1 - 7.5e-10 39.2 0.4 2.4e-09 37.6 0.3 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO15874.1 - 4.7e-09 36.0 0.0 1.8e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDO15874.1 - 0.0087 15.6 0.2 0.0087 15.6 0.2 2.6 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase PhaG_MnhG_YufB PF03334.9 EDO15874.1 - 1.3 9.1 6.5 0.86 9.6 0.0 3.1 3 1 1 4 4 4 0 Na+/H+ antiporter subunit Steroid_dh PF02544.11 EDO15875.1 - 1.2e-07 31.6 8.0 1.2e-07 31.6 5.6 1.9 1 1 1 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2127 PF09900.4 EDO15875.1 - 0.016 15.2 1.4 0.032 14.2 1.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) Ribosomal_L34e PF01199.13 EDO15876.1 - 2.6e-12 46.8 0.8 2.6e-12 46.8 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L34e DNA_gyraseB PF00204.20 EDO15876.1 - 0.024 13.8 2.2 0.026 13.7 1.5 1.1 1 0 0 1 1 1 0 DNA gyrase B DUF1428 PF07237.6 EDO15876.1 - 0.092 12.6 0.1 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1428) Phage_Gp14 PF10666.4 EDO15876.1 - 0.097 12.5 1.8 0.12 12.2 1.2 1.1 1 0 0 1 1 1 0 Phage protein Gp14 KAP PF05804.7 EDO15876.1 - 0.11 10.4 1.0 0.13 10.1 0.7 1.0 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) zf-3CxxC PF13695.1 EDO15876.1 - 0.13 12.4 1.5 0.14 12.3 1.1 1.1 1 0 0 1 1 1 0 Zinc-binding domain Ribonuc_L-PSP PF01042.16 EDO15877.1 - 1e-40 138.2 0.4 1.1e-40 138.1 0.3 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Rab3-GTPase_cat PF13890.1 EDO15877.1 - 0.082 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Phage_rep_org_N PF09681.5 EDO15877.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.4 1 1 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) CCDC50_N PF15295.1 EDO15878.1 - 0.0073 16.2 3.9 0.0091 15.9 2.7 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus DUF4094 PF13334.1 EDO15878.1 - 0.013 15.9 0.1 0.015 15.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Sugar_tr PF00083.19 EDO15878.1 - 0.099 11.1 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter OmpH PF03938.9 EDO15878.1 - 1.3 8.9 7.4 1.6 8.6 5.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Transp_cyt_pur PF02133.10 EDO15879.1 - 5.8e-84 282.1 40.8 7e-84 281.9 28.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HAD_2 PF13419.1 EDO15880.1 - 1.6e-11 44.7 0.0 2.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO15880.1 - 3.3e-09 37.4 0.0 8.2e-09 36.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDO15880.1 - 4e-07 29.6 0.0 7.5e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EDO15880.1 - 0.05 13.7 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase V_ATPase_I PF01496.14 EDO15881.1 - 3.3e-280 931.2 15.3 3.8e-280 931.1 10.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family T2SM PF04612.7 EDO15881.1 - 0.081 12.7 0.1 0.24 11.1 0.1 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M HSP70 PF00012.15 EDO15882.1 - 3.4e-54 183.8 2.3 3.4e-54 183.8 1.6 3.0 2 2 1 3 3 3 1 Hsp70 protein RabGAP-TBC PF00566.13 EDO15883.1 - 4.6e-37 127.5 2.4 8.3e-37 126.7 1.7 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mito_carr PF00153.22 EDO15884.1 - 4.7e-69 228.1 7.4 1.6e-24 85.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TRAP_alpha PF03896.11 EDO15885.1 - 0.0016 17.4 3.8 0.0016 17.4 2.7 2.4 3 0 0 3 3 3 1 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 EDO15885.1 - 0.002 16.7 11.7 0.0026 16.3 8.1 1.2 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 EDO15885.1 - 0.02 12.8 13.9 0.037 11.9 9.7 1.4 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.1 EDO15885.1 - 0.026 14.2 4.8 0.38 10.4 3.0 2.6 2 0 0 2 2 2 0 FAM176 family RRN3 PF05327.6 EDO15885.1 - 0.051 11.6 10.4 0.085 10.9 7.2 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2890 PF11081.3 EDO15885.1 - 0.12 12.4 12.1 0.29 11.1 8.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF506 PF04720.7 EDO15885.1 - 0.19 11.3 5.2 0.2 11.2 2.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF506) BSP_II PF05432.6 EDO15885.1 - 0.24 10.6 18.3 0.49 9.6 12.7 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Spb1_C PF07780.7 EDO15885.1 - 0.35 10.3 13.1 0.066 12.6 6.5 1.7 2 0 0 2 2 2 0 Spb1 C-terminal domain Ycf1 PF05758.7 EDO15885.1 - 0.37 8.4 11.6 0.21 9.2 6.8 1.3 1 1 0 1 1 1 0 Ycf1 DUF740 PF05340.7 EDO15885.1 - 0.37 9.0 11.1 0.58 8.4 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) alpha-hel2 PF14456.1 EDO15885.1 - 0.42 9.3 6.1 0.91 8.2 4.2 1.6 1 0 0 1 1 1 0 Alpha-helical domain 2 DUF4628 PF15429.1 EDO15885.1 - 0.51 9.7 6.2 0.86 8.9 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Nucleoplasmin PF03066.10 EDO15885.1 - 2 7.8 24.1 0.41 10.1 12.7 2.2 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 EDO15885.1 - 3.2 5.6 12.5 5.3 4.9 8.7 1.3 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 EDO15885.1 - 6.4 5.8 17.4 13 4.8 12.0 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4448 PF14610.1 EDO15886.1 - 3.7e-49 166.7 0.1 5.3e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Sen15 PF09631.5 EDO15887.1 - 9.4e-27 93.2 0.0 1.1e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein P16-Arc PF04699.9 EDO15887.1 - 0.12 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Tom37_C PF11801.3 EDO15888.1 - 3.1e-48 163.7 2.0 4.4e-48 163.3 1.4 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EDO15888.1 - 7.7e-26 90.1 0.2 2.8e-25 88.3 0.1 1.9 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein Suf PF05843.9 EDO15889.1 - 1.2e-71 241.7 24.3 3e-70 237.1 9.9 4.0 2 2 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EDO15889.1 - 0.012 15.2 5.5 0.036 13.6 0.0 3.8 5 0 0 5 5 5 0 TPR repeat TPR_17 PF13431.1 EDO15889.1 - 0.012 15.7 0.5 2.4 8.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDO15889.1 - 0.052 14.1 0.0 5 8.0 0.0 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDO15889.1 - 0.063 13.7 0.0 11 6.6 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDO15889.1 - 0.09 13.1 0.0 23 5.4 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Herpes_U15 PF05613.6 EDO15889.1 - 0.094 13.0 1.7 0.33 11.3 1.1 1.9 1 0 0 1 1 1 0 Human herpesvirus U15 protein Tht1 PF04163.7 EDO15890.1 - 1.1e-36 126.3 18.6 1.4e-36 126.0 12.9 1.2 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein Baculo_PEP_C PF04513.7 EDO15890.1 - 0.09 12.5 6.9 2 8.2 0.6 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sipho_Gp157 PF05565.6 EDO15890.1 - 0.47 10.0 8.7 4.2 6.9 2.1 2.7 3 0 0 3 3 3 0 Siphovirus Gp157 DUF948 PF06103.6 EDO15890.1 - 0.84 9.5 4.7 5 7.0 0.3 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.5 EDO15890.1 - 3.2 7.8 9.0 1.8 8.7 4.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Kinesin PF00225.18 EDO15891.1 - 6.5e-60 202.5 8.4 6.5e-60 202.5 5.8 2.1 2 0 0 2 2 2 1 Kinesin motor domain V-ATPase_C PF03223.10 EDO15892.1 - 1.3e-120 402.7 10.7 1.4e-120 402.6 7.4 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF2193 PF09959.4 EDO15892.1 - 0.022 13.0 0.5 1.1 7.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2193) Imm20 PF15568.1 EDO15892.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 20 DUF536 PF04394.9 EDO15892.1 - 0.17 11.6 3.1 37 4.1 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function, DUF536 PCI PF01399.22 EDO15893.1 - 1.8e-21 76.4 0.1 1.8e-21 76.4 0.1 3.0 3 0 0 3 3 3 1 PCI domain TPR_8 PF13181.1 EDO15893.1 - 0.046 13.5 0.3 41 4.2 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF4259 PF14078.1 EDO15893.1 - 0.17 12.4 6.2 16 6.0 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4259) Rootletin PF15035.1 EDO15894.1 - 0.0022 18.0 9.1 0.0028 17.6 6.3 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Apolipoprotein PF01442.13 EDO15894.1 - 0.0026 17.3 3.1 0.0079 15.7 1.7 1.8 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Spectrin PF00435.16 EDO15894.1 - 0.032 14.5 5.9 0.06 13.6 4.1 1.4 1 0 0 1 1 1 0 Spectrin repeat Phage_GPO PF05929.6 EDO15894.1 - 0.57 9.3 3.9 0.63 9.2 2.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF972 PF06156.8 EDO15894.1 - 3.1 8.1 10.1 0.54 10.6 3.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF2013 PF09431.5 EDO15895.1 - 3.5e-38 130.5 17.1 3.5e-38 130.5 11.8 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) Glyco_hydro_16 PF00722.16 EDO15896.1 - 6.2e-44 149.4 3.3 6.2e-44 149.4 2.3 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 WAP PF00095.16 EDO15896.1 - 0.0027 17.6 3.7 0.0059 16.5 2.6 1.5 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Nodulin_late PF07127.6 EDO15896.1 - 0.027 14.5 0.6 0.06 13.4 0.4 1.5 1 0 0 1 1 1 0 Late nodulin protein Chitin_bind_1 PF00187.14 EDO15896.1 - 0.055 13.4 9.9 0.091 12.7 6.9 1.3 1 0 0 1 1 1 0 Chitin recognition protein ApbA_C PF08546.6 EDO15897.1 - 3.6e-24 85.1 0.2 6.6e-24 84.2 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EDO15897.1 - 3.1e-21 75.3 0.0 4.6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EDO15897.1 - 0.026 14.6 0.0 0.075 13.1 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EDO15897.1 - 0.031 14.5 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 EDO15897.1 - 0.15 11.8 0.3 1.1 9.0 0.1 2.4 3 0 0 3 3 3 0 ThiF family DAO PF01266.19 EDO15897.1 - 0.15 10.8 0.1 0.21 10.4 0.1 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ferric_reduct PF01794.14 EDO15898.1 - 1.9e-22 79.6 6.8 1.9e-22 79.6 4.7 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EDO15898.1 - 6.9e-16 58.0 0.0 1.6e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EDO15898.1 - 1.6e-15 57.3 0.1 2.9e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain CFEM PF05730.6 EDO15898.1 - 0.003 17.3 2.1 0.0066 16.2 1.4 1.5 1 0 0 1 1 1 1 CFEM domain Ribosomal_L44 PF00935.14 EDO15898.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L44 Ferric_reduct PF01794.14 EDO15899.1 - 1.4e-20 73.6 7.9 1.4e-20 73.6 5.5 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EDO15899.1 - 4.1e-17 61.9 0.0 9.7e-17 60.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EDO15899.1 - 7e-13 48.7 0.0 1.5e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 EDO15899.1 - 0.034 14.2 0.4 0.034 14.2 0.3 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4405) CFEM PF05730.6 EDO15899.1 - 0.057 13.2 3.2 0.1 12.4 2.2 1.4 1 0 0 1 1 1 0 CFEM domain D123 PF07065.9 EDO15900.1 - 4e-113 377.4 6.3 5.2e-113 377.0 4.4 1.1 1 0 0 1 1 1 1 D123 Cpn60_TCP1 PF00118.19 EDO15901.1 - 5.1e-135 450.8 12.0 5.8e-135 450.6 8.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 EDO15901.1 - 0.018 14.3 1.9 0.33 10.1 0.1 2.9 3 0 0 3 3 3 0 DeoC/LacD family aldolase CDP-OH_P_transf PF01066.16 EDO15902.1 - 7.1e-17 61.5 5.1 1.1e-16 60.9 3.5 1.4 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase TctB PF07331.6 EDO15902.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.6 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family BPL_N PF09825.4 EDO15903.1 - 5e-125 417.0 0.0 6.4e-125 416.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EDO15903.1 - 1.2e-14 54.3 0.2 5.2e-14 52.3 0.1 2.1 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EDO15903.1 - 8.3e-11 41.4 0.0 1.6e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain FUSC PF04632.7 EDO15904.1 - 4.4 5.6 17.2 72 1.5 12.0 1.9 1 1 0 1 1 1 0 Fusaric acid resistance protein family RNA_pol_Rpb1_1 PF04997.7 EDO15906.1 - 9.4e-97 324.2 0.0 1.1e-96 323.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 zf-C4pol PF14260.1 EDO15906.1 - 2.7 8.0 7.5 0.63 10.0 1.6 2.2 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Scm3 PF10384.4 EDO15907.1 - 3e-23 81.0 0.3 3e-23 81.0 0.2 2.0 2 0 0 2 2 2 1 Centromere protein Scm3 CHCH PF06747.8 EDO15908.1 - 1.3e-05 24.9 3.2 2.3e-05 24.1 2.2 1.5 1 0 0 1 1 1 1 CHCH domain CbiK PF06180.6 EDO15908.1 - 0.035 13.1 0.1 0.043 12.9 0.1 1.1 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) MOFRL PF05161.8 EDO15908.1 - 0.036 14.1 0.0 0.04 14.0 0.0 1.1 1 0 0 1 1 1 0 MOFRL family Sec31 PF11549.3 EDO15909.1 - 1.3e-27 95.2 5.1 6.2e-27 92.9 3.5 2.3 1 0 0 1 1 1 1 Protein transport protein SEC31 WD40 PF00400.27 EDO15909.1 - 7.9e-14 50.9 10.5 8.8e-06 25.4 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 EDO15909.1 - 2.3e-09 37.1 0.0 6.9e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 EDO15909.1 - 0.00062 19.5 0.4 0.0023 17.7 0.3 2.0 1 1 0 1 1 1 1 Prp18 domain Sugar_tr PF00083.19 EDO15910.1 - 7.8e-123 410.3 30.5 9.3e-123 410.1 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO15910.1 - 3.1e-22 78.7 45.8 3.4e-20 72.0 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.8 EDO15910.1 - 0.022 14.8 0.2 0.022 14.8 0.1 3.5 3 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 EDO15910.1 - 1.1 8.2 13.0 1.8 7.5 9.0 1.3 1 0 0 1 1 1 0 Fms-interacting protein GOLD_2 PF13897.1 EDO15910.1 - 3.2 8.0 8.9 1.3 9.2 0.1 3.6 3 1 1 4 4 4 0 Golgi-dynamics membrane-trafficking Arf PF00025.16 EDO15911.1 - 3.2e-78 260.9 0.0 3.7e-78 260.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDO15911.1 - 2.2e-14 53.1 0.0 2.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EDO15911.1 - 6.1e-14 51.6 0.0 7.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EDO15911.1 - 4.3e-11 42.1 0.5 4.8e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDO15911.1 - 8.6e-11 41.4 0.0 1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDO15911.1 - 1.4e-10 41.6 0.0 2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDO15911.1 - 8.6e-06 25.6 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDO15911.1 - 0.0058 16.0 0.0 0.027 13.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 EDO15911.1 - 0.006 16.0 0.2 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EDO15911.1 - 0.0071 16.2 0.1 0.011 15.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EDO15911.1 - 0.021 14.5 0.5 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 EDO15911.1 - 0.031 14.5 0.1 0.058 13.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.13 EDO15911.1 - 0.037 13.0 0.1 0.056 12.5 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.14 EDO15911.1 - 0.075 12.4 0.1 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_L29 PF00831.18 EDO15912.1 - 3.2e-17 61.9 2.7 3.2e-17 61.9 1.9 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Annexin PF00191.15 EDO15912.1 - 0.062 13.2 0.2 0.16 11.8 0.1 1.8 1 1 0 1 1 1 0 Annexin DUF4404 PF14357.1 EDO15912.1 - 0.14 12.6 1.9 0.61 10.5 1.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Mhr1 PF12829.2 EDO15912.1 - 0.33 10.7 3.5 0.26 11.1 1.0 1.9 1 1 1 2 2 2 0 Transcriptional regulation of mitochondrial recombination MRP-L47 PF06984.8 EDO15912.1 - 0.58 10.0 3.4 0.5 10.3 0.5 2.2 2 2 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) R3H PF01424.17 EDO15913.1 - 1e-09 37.9 0.0 2.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 R3H domain Aminotran_1_2 PF00155.16 EDO15914.1 - 7.7e-42 143.5 0.0 9.6e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EDO15914.1 - 1e-07 31.3 0.0 1.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EDO15914.1 - 3.8e-07 29.1 0.0 9.2e-07 27.9 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EDO15914.1 - 2.6e-06 26.0 0.0 3.5e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EDO15914.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Alliinase_C PF04864.8 EDO15914.1 - 0.034 12.7 0.0 0.077 11.6 0.0 1.6 1 1 0 1 1 1 0 Allinase Phos_pyr_kin PF08543.7 EDO15915.1 - 8.8e-11 41.4 0.0 1.2e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EDO15915.1 - 2.9e-08 33.1 0.2 2.5e-06 26.8 0.0 2.8 2 1 0 2 2 2 2 pfkB family carbohydrate kinase SKN1 PF03935.10 EDO15916.1 - 2.6e-256 850.6 5.6 3.2e-256 850.2 3.9 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF1438 PF07270.6 EDO15916.1 - 0.041 13.7 2.2 3.2 7.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1438) SIS PF01380.17 EDO15917.1 - 2.9e-12 46.3 0.1 4.4e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EDO15917.1 - 5.2e-09 35.9 0.1 1.1e-05 25.1 0.0 2.3 1 1 0 1 1 1 1 SIS domain DUF230 PF03003.11 EDO15917.1 - 0.24 10.9 4.5 0.42 10.1 0.1 2.3 2 0 0 2 2 2 0 Poxvirus proteins of unknown function DUF2604 PF10790.4 EDO15918.1 - 0.038 14.1 0.2 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) DUF946 PF06101.6 EDO15919.1 - 2.8e-10 38.8 8.6 2.3e-09 35.8 5.2 2.7 1 1 1 2 2 2 1 Plant protein of unknown function (DUF946) NCA2 PF08637.5 EDO15920.1 - 3e-93 311.8 11.1 3e-93 311.8 7.7 1.7 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 SH3_1 PF00018.23 EDO15921.1 - 8.1e-14 50.7 0.0 1.3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO15921.1 - 4.9e-13 48.4 0.5 8e-13 47.7 0.0 1.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EDO15921.1 - 5.9e-12 44.8 0.0 9.3e-12 44.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF605 PF04652.11 EDO15921.1 - 0.00013 21.5 20.2 0.00014 21.4 14.0 1.1 1 0 0 1 1 1 1 Vta1 like PAT1 PF09770.4 EDO15921.1 - 0.024 12.8 27.8 0.025 12.8 19.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 EDO15921.1 - 0.1 12.2 6.9 0.12 12.1 4.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4596 PF15363.1 EDO15921.1 - 0.23 11.3 1.4 0.7 9.8 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) TFIIA PF03153.8 EDO15921.1 - 5.2 6.8 19.6 7 6.4 13.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tmemb_170 PF10190.4 EDO15922.1 - 0.00099 19.1 4.0 0.0013 18.7 2.8 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF457 PF04307.9 EDO15922.1 - 0.33 10.2 3.1 0.62 9.3 2.0 1.7 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Proteasome PF00227.21 EDO15923.1 - 3.9e-59 199.1 1.0 4.9e-59 198.8 0.7 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO15923.1 - 2.1e-13 49.2 0.2 4.2e-13 48.3 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature WW PF00397.21 EDO15924.1 - 4.9e-11 42.2 4.0 2.5e-08 33.6 1.0 2.5 2 0 0 2 2 2 2 WW domain FF PF01846.14 EDO15924.1 - 2.2e-09 37.1 13.9 3.9e-09 36.3 1.9 4.4 4 0 0 4 4 4 2 FF domain FRQ PF09421.5 EDO15925.1 - 1.4 6.6 7.9 2 6.0 5.5 1.1 1 0 0 1 1 1 0 Frequency clock protein UQ_con PF00179.21 EDO15926.1 - 1.8e-38 131.1 0.2 2e-38 130.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO15926.1 - 4.5e-07 29.6 0.0 4.9e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDO15926.1 - 0.00017 21.4 0.1 0.0002 21.2 0.1 1.3 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.6 EDO15926.1 - 0.0013 18.2 0.2 0.0031 16.9 0.0 1.6 1 1 0 2 2 2 1 Ubiquitin-fold modifier-conjugating enzyme 1 SYF2 PF08231.7 EDO15928.1 - 1e-09 38.6 24.7 1e-09 38.6 17.1 1.8 2 0 0 2 2 2 1 SYF2 splicing factor Secretin_N PF03958.12 EDO15928.1 - 0.0099 16.0 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial type II/III secretion system short domain DUF1318 PF07027.7 EDO15928.1 - 3.5 7.9 8.6 1.9 8.7 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) Glyco_hydro_4C PF11975.3 EDO15928.1 - 4.6 6.9 14.3 0.17 11.6 4.3 2.0 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain Utp8 PF10395.4 EDO15929.1 - 2.9e-247 822.3 29.8 3.2e-247 822.1 20.7 1.0 1 0 0 1 1 1 1 Utp8 family DUF2305 PF10230.4 EDO15930.1 - 7.3e-72 241.9 0.6 8.4e-72 241.7 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EDO15930.1 - 0.00037 20.4 0.0 0.00052 19.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO15930.1 - 0.0041 16.8 0.0 0.0063 16.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 EDO15930.1 - 0.021 13.6 0.6 3.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) DUF3089 PF11288.3 EDO15930.1 - 0.025 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Sulfate_transp PF00916.15 EDO15931.1 - 1.8e-50 171.5 10.3 3.4e-50 170.6 7.1 1.5 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 EDO15931.1 - 1.8e-13 49.9 1.5 3.6e-13 48.9 1.0 1.5 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 EDO15931.1 - 0.0026 17.5 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Asn_synthase PF00733.16 EDO15932.1 - 1.4e-69 234.4 0.0 1.9e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EDO15932.1 - 4.2e-33 113.7 0.0 7.7e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EDO15932.1 - 2.3e-28 98.8 0.0 1.4e-26 92.9 0.0 2.3 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EDO15932.1 - 2.5e-07 30.1 0.0 4.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EDO15932.1 - 2.8e-05 23.0 0.0 0.058 12.1 0.0 3.0 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EDO15932.1 - 0.012 14.5 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase F-box-like PF12937.2 EDO15933.1 - 0.00092 18.8 0.0 0.0025 17.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Phage_int_SAM_2 PF12834.2 EDO15933.1 - 0.03 14.7 0.0 0.1 12.9 0.0 2.0 1 0 0 1 1 1 0 Phage integrase, N-terminal zf-C3HC4_4 PF15227.1 EDO15935.1 - 2.7e-11 43.1 11.0 2.7e-11 43.1 7.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EDO15935.1 - 8.2e-08 31.8 13.5 3.1e-07 29.9 4.3 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO15935.1 - 8.6e-08 32.0 9.6 8.6e-08 32.0 6.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO15935.1 - 1.2e-07 31.2 9.6 1.2e-07 31.2 6.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO15935.1 - 7.6e-07 28.7 2.1 1.7e-06 27.6 1.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EDO15935.1 - 9.9e-07 28.4 9.6 9.9e-07 28.4 6.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EDO15935.1 - 1.9e-05 24.2 7.7 1.9e-05 24.2 5.3 2.5 2 1 0 2 2 2 1 zinc-RING finger domain DZR PF12773.2 EDO15935.1 - 0.0019 17.9 10.6 0.34 10.7 0.2 2.7 2 1 0 2 2 2 2 Double zinc ribbon zf-rbx1 PF12678.2 EDO15935.1 - 0.0099 15.9 5.8 0.0099 15.9 4.0 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDO15935.1 - 0.026 14.3 2.0 0.026 14.3 1.4 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EDO15935.1 - 0.2 11.2 12.7 0.061 12.8 5.9 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Zn-ribbon_8 PF09723.5 EDO15935.1 - 0.59 10.1 8.2 4.1 7.4 0.4 2.9 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 EDO15935.1 - 0.64 9.6 4.3 62 3.2 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain RNHCP PF12647.2 EDO15935.1 - 1 9.2 11.1 1 9.2 0.3 3.2 2 1 1 3 3 3 0 RNHCP domain zinc_ribbon_4 PF13717.1 EDO15935.1 - 1.2 8.9 4.9 65 3.3 0.1 3.7 3 0 0 3 3 3 0 zinc-ribbon domain Paired_CXXCH_1 PF09699.5 EDO15935.1 - 2.2 7.8 7.0 5.7 6.5 0.1 3.2 3 0 0 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) FANCL_C PF11793.3 EDO15935.1 - 5 7.1 10.3 19 5.3 5.5 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EDO15935.1 - 5.5 6.6 18.9 0.071 12.6 1.8 3.0 3 1 0 3 3 2 0 RING/Ubox like zinc-binding domain COX7a PF02238.10 EDO15936.1 - 0.073 12.8 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Sigma_reg_N PF13800.1 EDO15937.1 - 0.016 15.1 0.9 2.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal zf-RING_2 PF13639.1 EDO15938.1 - 1.7e-08 34.1 7.2 5.8e-08 32.4 5.0 2.0 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO15938.1 - 5.2e-07 29.6 8.0 6.2e-07 29.4 2.4 2.8 3 0 0 3 3 3 1 RING-H2 zinc finger FANCL_C PF11793.3 EDO15938.1 - 2.9e-05 23.9 5.7 0.00011 22.0 4.0 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EDO15938.1 - 4.1e-05 23.3 1.3 0.00013 21.7 0.9 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EDO15938.1 - 0.036 14.1 6.3 0.086 12.9 4.4 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 EDO15938.1 - 0.097 12.6 6.7 0.28 11.2 4.6 1.9 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 EDO15938.1 - 0.15 12.1 12.2 0.071 13.1 5.7 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EDO15938.1 - 0.17 11.4 8.7 0.31 10.6 0.7 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 EDO15938.1 - 0.27 11.0 3.2 7.7 6.3 0.5 2.6 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-C3HC4 PF00097.20 EDO15938.1 - 4.8 6.9 18.3 0.074 12.7 5.4 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Glyco_transf_8 PF01501.15 EDO15939.1 - 1.9e-09 37.2 16.5 1.3e-07 31.1 11.4 2.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleoside_tran PF01733.13 EDO15939.1 - 0.015 14.5 0.4 0.025 13.7 0.3 1.3 1 0 0 1 1 1 0 Nucleoside transporter Mannosyl_trans3 PF11051.3 EDO15939.1 - 0.051 12.9 3.2 0.14 11.4 2.0 2.0 1 1 0 1 1 1 0 Mannosyltransferase putative AMP-binding PF00501.23 EDO15940.1 - 1.4e-79 267.4 0.0 2.1e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_S3_C PF00189.15 EDO15941.1 - 1.5e-15 57.1 0.1 2.7e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EDO15941.1 - 8.2e-13 47.7 0.1 3.5e-12 45.7 0.1 2.0 2 0 0 2 2 2 1 KH domain SHR3_chaperone PF08229.6 EDO15942.1 - 7.1e-84 279.6 0.8 8.6e-84 279.3 0.5 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 PsaA_PsaB PF00223.14 EDO15942.1 - 0.011 13.8 0.0 0.012 13.7 0.0 1.0 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein MARVEL PF01284.18 EDO15942.1 - 0.039 13.7 4.1 0.14 11.9 2.7 1.8 1 1 0 1 1 1 0 Membrane-associating domain DUF4271 PF14093.1 EDO15942.1 - 0.066 12.8 4.8 0.091 12.4 3.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF808 PF05661.7 EDO15942.1 - 0.096 11.4 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) DUF788 PF05620.6 EDO15942.1 - 0.55 10.0 3.9 0.19 11.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF788) DUF3899 PF13038.1 EDO15942.1 - 7.9 6.7 9.9 5.8 7.1 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) Ribosomal_L22 PF00237.14 EDO15943.1 - 1.2e-19 70.1 0.0 2.2e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Nop14 PF04147.7 EDO15944.1 - 0.024 12.5 24.6 0.035 12.0 17.0 1.2 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EDO15944.1 - 0.074 12.2 19.6 0.096 11.9 13.6 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF605 PF04652.11 EDO15944.1 - 0.71 9.2 20.6 0.86 8.9 14.3 1.1 1 0 0 1 1 1 0 Vta1 like DUF2201_N PF13203.1 EDO15944.1 - 1.8 7.6 14.3 2.8 7.0 9.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain TFIIF_alpha PF05793.7 EDO15944.1 - 2.6 6.2 24.2 3.6 5.8 16.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Suf PF05843.9 EDO15944.1 - 4.3 6.9 16.3 7.5 6.1 11.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 EDO15944.1 - 9.1 3.8 17.4 12 3.4 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CD20 PF04103.10 EDO15945.1 - 0.021 14.7 3.8 0.24 11.3 0.1 2.6 2 1 0 2 2 2 0 CD20-like family FA_desaturase PF00487.19 EDO15945.1 - 0.059 12.8 1.4 0.14 11.6 0.6 1.7 2 0 0 2 2 2 0 Fatty acid desaturase BAF1_ABF1 PF04684.8 EDO15946.1 - 0.00047 19.1 8.1 0.00057 18.8 5.6 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Zip PF02535.17 EDO15946.1 - 0.026 13.5 3.4 0.033 13.1 2.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EDO15946.1 - 0.061 12.6 12.4 0.093 12.1 8.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HEAT PF02985.17 EDO15947.1 - 5.5e-31 103.8 16.1 0.00045 20.0 0.0 13.0 13 1 1 14 14 14 8 HEAT repeat HEAT_2 PF13646.1 EDO15947.1 - 5.2e-21 74.7 0.0 7.1e-05 23.0 0.0 7.3 3 2 4 7 7 7 6 HEAT repeats Vac14_Fab1_bd PF12755.2 EDO15947.1 - 5.8e-08 33.0 10.1 0.14 12.5 0.3 6.6 3 2 6 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EDO15947.1 - 0.00041 20.7 6.2 1.5 9.4 0.0 6.7 8 1 0 8 8 8 1 HEAT-like repeat Rif1_N PF12231.3 EDO15947.1 - 0.0057 15.6 7.6 0.0097 14.9 1.5 2.9 3 0 0 3 3 3 1 Rap1-interacting factor 1 N terminal DUF2392 PF10288.4 EDO15947.1 - 0.013 15.8 0.9 1.3 9.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2392) Arm PF00514.18 EDO15947.1 - 0.43 10.4 11.5 23 4.9 0.0 5.9 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat SNARE PF05739.14 EDO15949.1 - 5.1e-12 45.3 8.8 1.4e-11 43.8 6.1 1.7 1 0 0 1 1 1 1 SNARE domain UvrD_C PF13361.1 EDO15949.1 - 0.0036 16.8 1.0 0.0055 16.2 0.7 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain TMPIT PF07851.8 EDO15949.1 - 0.12 11.3 3.7 0.061 12.3 1.0 1.6 2 0 0 2 2 2 0 TMPIT-like protein MHC_II_beta PF00969.14 EDO15949.1 - 0.69 9.9 2.6 1.8 8.5 0.6 2.5 1 1 1 2 2 2 0 Class II histocompatibility antigen, beta domain Sds3 PF08598.6 EDO15950.1 - 6.5e-51 172.7 0.2 6.5e-51 172.7 0.1 2.7 2 1 0 2 2 2 1 Sds3-like Cys_Met_Meta_PP PF01053.15 EDO15951.1 - 2.7e-145 483.4 0.0 3.1e-145 483.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 EDO15951.1 - 4e-05 22.1 0.0 5.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 EDO15951.1 - 0.0044 16.0 0.0 0.0066 15.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EDO15951.1 - 0.034 13.2 0.0 0.27 10.3 0.0 2.0 2 0 0 2 2 2 0 Beta-eliminating lyase GDC-P PF02347.11 EDO15951.1 - 0.049 12.3 0.0 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein DUF775 PF05603.7 EDO15952.1 - 3.7e-58 196.3 0.0 4.2e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) tRNA-synt_1c PF00749.16 EDO15953.1 - 1.9e-111 371.7 0.0 2.6e-111 371.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Flu_B_M2 PF04772.7 EDO15953.1 - 0.26 11.3 1.6 0.5 10.4 0.1 2.2 3 0 0 3 3 3 0 Influenza B matrix protein 2 (BM2) AAA_23 PF13476.1 EDO15954.1 - 5e-18 66.1 4.7 5e-18 66.1 3.3 6.2 2 2 2 4 4 4 1 AAA domain SMC_N PF02463.14 EDO15954.1 - 4.4e-16 58.7 42.6 1.5e-15 57.0 29.6 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO15954.1 - 5.3e-08 33.1 3.1 5.3e-08 33.1 2.1 4.1 2 2 2 4 4 4 2 AAA domain AAA_29 PF13555.1 EDO15954.1 - 0.00079 18.9 0.0 0.0023 17.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EDO15954.1 - 0.0026 17.1 0.0 0.0074 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF3376 PF11856.3 EDO15954.1 - 0.0056 16.1 1.7 0.13 11.6 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3376) Clp1 PF06807.9 EDO15955.1 - 6.5e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 G-alpha PF00503.15 EDO15955.1 - 0.00015 20.6 0.0 0.00041 19.1 0.0 1.7 1 0 0 1 1 1 1 G-protein alpha subunit AAA_18 PF13238.1 EDO15955.1 - 0.043 14.1 0.1 0.82 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EDO15956.1 - 2.4e-93 309.2 0.0 1.8e-47 160.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO15956.1 - 7.5e-15 54.6 0.0 6.9e-08 31.8 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EDO15956.1 - 6.5e-12 46.3 0.3 9.1e-07 29.7 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EDO15956.1 - 1.8e-11 44.3 0.4 0.00042 20.3 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 EDO15956.1 - 1e-10 41.0 0.0 0.00053 19.1 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin AAA_22 PF13401.1 EDO15956.1 - 1.1e-10 41.7 0.2 0.0057 16.7 0.0 4.9 2 2 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EDO15956.1 - 2.2e-10 40.5 0.0 0.0002 21.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EDO15956.1 - 5.5e-10 39.4 0.0 0.00084 19.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EDO15956.1 - 1.3e-09 38.0 0.0 0.003 17.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EDO15956.1 - 1.5e-09 37.7 0.1 0.0033 17.1 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDO15956.1 - 7.6e-09 35.9 0.3 0.00019 21.7 0.0 3.4 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.8 EDO15956.1 - 3.7e-08 32.5 2.6 0.00026 19.8 0.0 3.1 4 0 0 4 4 3 2 TIP49 C-terminus RNA_helicase PF00910.17 EDO15956.1 - 1.5e-07 31.5 0.0 0.011 15.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 EDO15956.1 - 3.1e-07 30.7 0.4 0.026 14.7 0.0 3.2 3 0 0 3 3 3 2 ABC transporter IstB_IS21 PF01695.12 EDO15956.1 - 5.4e-07 29.1 0.1 0.021 14.2 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EDO15956.1 - 1.2e-06 28.1 0.8 0.059 13.1 0.1 2.7 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 EDO15956.1 - 1.4e-06 28.3 0.0 0.028 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 EDO15956.1 - 3.8e-06 26.6 0.1 0.0019 18.0 0.1 3.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.16 EDO15956.1 - 4.2e-06 26.0 0.4 0.044 12.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EDO15956.1 - 7.3e-06 25.6 0.0 0.039 13.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EDO15956.1 - 1.1e-05 25.3 0.0 0.096 12.5 0.0 3.0 2 0 0 2 2 2 2 Shikimate kinase NACHT PF05729.7 EDO15956.1 - 2.3e-05 24.1 0.1 0.53 9.9 0.0 3.4 3 0 0 3 3 3 2 NACHT domain AAA_25 PF13481.1 EDO15956.1 - 3.1e-05 23.4 3.5 2.3 7.5 0.0 4.4 2 2 2 5 5 5 2 AAA domain Cytidylate_kin2 PF13189.1 EDO15956.1 - 4.5e-05 23.4 0.0 0.0043 16.9 0.0 2.7 3 0 0 3 3 2 1 Cytidylate kinase-like family SRPRB PF09439.5 EDO15956.1 - 4.9e-05 22.6 0.0 1.3 8.1 0.0 3.6 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Sigma54_activ_2 PF14532.1 EDO15956.1 - 0.00011 22.2 0.1 0.68 9.9 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain Rad17 PF03215.10 EDO15956.1 - 0.00011 20.9 0.1 0.12 11.0 0.0 3.0 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EDO15956.1 - 0.0002 20.9 0.0 0.51 9.8 0.0 2.7 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 EDO15956.1 - 0.00022 20.7 0.0 0.24 10.8 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain NB-ARC PF00931.17 EDO15956.1 - 0.00027 19.8 0.0 0.33 9.7 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain DUF815 PF05673.8 EDO15956.1 - 0.00047 19.1 0.0 0.17 10.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EDO15956.1 - 0.00055 19.7 0.6 2.6 7.6 0.0 3.6 3 1 1 4 4 3 1 Archaeal ATPase CPT PF07931.7 EDO15956.1 - 0.00096 18.8 0.0 0.021 14.4 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 EDO15956.1 - 0.0016 17.5 0.1 1.3 8.0 0.0 3.1 3 0 0 3 3 3 1 KaiC Parvo_NS1 PF01057.12 EDO15956.1 - 0.0023 16.8 0.0 1.6 7.4 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 EDO15956.1 - 0.0025 17.4 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EDO15956.1 - 0.0054 16.2 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 EDO15956.1 - 0.0055 15.9 0.1 1.6 7.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein UPF0079 PF02367.12 EDO15956.1 - 0.014 15.0 0.0 6.3 6.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EDO15956.1 - 0.018 14.5 0.0 6.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 EDO15956.1 - 0.018 14.9 2.4 5.4 6.8 0.0 3.7 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 EDO15956.1 - 0.02 14.6 0.0 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 NTPase DUF258 PF03193.11 EDO15956.1 - 0.048 12.8 0.0 0.93 8.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AFG1_ATPase PF03969.11 EDO15956.1 - 0.052 12.3 0.0 9 4.9 0.0 2.6 2 0 0 2 2 2 0 AFG1-like ATPase MMR_HSR1 PF01926.18 EDO15956.1 - 0.059 13.3 0.0 3 7.8 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO15956.1 - 0.069 12.4 0.1 2.1 7.6 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B IPT PF01745.11 EDO15956.1 - 0.093 11.8 1.0 20 4.2 0.0 3.0 3 0 0 3 3 3 0 Isopentenyl transferase AAA_29 PF13555.1 EDO15956.1 - 0.1 12.1 0.0 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2456 PF10445.4 EDO15957.1 - 1.4e-38 130.6 4.3 2.7e-38 129.7 3.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) FtsX PF02687.16 EDO15957.1 - 0.02 14.6 9.2 0.68 9.7 0.7 2.3 2 0 0 2 2 2 0 FtsX-like permease family Creatinase_N PF01321.13 EDO15960.1 - 4.2e-11 43.4 0.0 1.1e-10 42.0 0.0 1.8 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain SapB_1 PF05184.10 EDO15960.1 - 3.4 7.6 6.5 84 3.1 0.2 4.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 MFS_1 PF07690.11 EDO15961.1 - 7.5e-36 123.5 23.1 7.5e-36 123.5 16.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDO15961.1 - 7.7e-06 24.3 4.7 1.7e-05 23.2 3.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fe-S_biosyn PF01521.15 EDO15962.1 - 1.4e-19 70.1 0.0 4e-19 68.5 0.0 1.8 2 1 0 2 2 2 1 Iron-sulphur cluster biosynthesis Glyco_hydro_2_N PF02837.13 EDO15962.1 - 0.02 14.4 0.7 0.03 13.8 0.5 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain NPR3 PF03666.8 EDO15963.1 - 3e-173 576.5 4.4 3e-173 576.5 3.1 2.4 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 UCH PF00443.24 EDO15964.1 - 2.3e-57 194.1 3.0 2.3e-57 194.1 2.1 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO15964.1 - 2.5e-19 69.8 0.8 2.5e-19 69.8 0.6 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Prenyltrans PF00432.16 EDO15964.1 - 0.19 11.3 0.0 0.53 9.8 0.0 1.7 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat DNA_RNApol_7kD PF03604.8 EDO15964.1 - 1.1 8.7 3.9 15 5.1 0.4 2.7 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_L11 PF00298.14 EDO15965.1 - 1.4e-27 95.6 1.0 2.2e-27 95.0 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 EDO15965.1 - 7.9e-27 92.5 0.2 1.3e-26 91.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.20 EDO15966.1 - 3.2e-62 210.0 0.0 4.9e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15966.1 - 5.6e-21 74.7 0.0 1.1e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO15966.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.27 EDO15967.1 - 2.7e-07 30.2 0.2 0.011 15.6 0.1 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EDO15967.1 - 0.012 15.8 0.1 2.3 8.5 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain DASH_Dam1 PF08653.5 EDO15967.1 - 0.17 11.6 0.5 0.47 10.2 0.3 1.8 1 0 0 1 1 1 0 DASH complex subunit Dam1 adh_short PF00106.20 EDO15968.1 - 3.6e-08 33.5 0.0 6.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO15968.1 - 5.5e-06 26.1 0.0 9.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Bac_rhodopsin PF01036.13 EDO15968.1 - 0.078 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein Cation_efflux PF01545.16 EDO15969.1 - 5.9e-84 281.5 8.7 8.2e-84 281.0 6.0 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EDO15969.1 - 3.3e-05 23.0 2.0 5.1e-05 22.4 1.4 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter TcpE PF12648.2 EDO15969.1 - 2 8.6 5.0 5.8 7.1 0.1 2.7 2 1 1 3 3 3 0 TcpE family SusD-like_2 PF12771.2 EDO15970.1 - 0.005 15.2 0.2 0.0067 14.8 0.1 1.2 1 0 0 1 1 1 1 Starch-binding associating with outer membrane Ribosomal_L18ae PF01775.12 EDO15972.1 - 3.5e-45 152.8 3.6 4.8e-45 152.4 2.5 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain LRR_4 PF12799.2 EDO15974.1 - 0.00068 19.1 22.1 0.0073 15.9 0.0 6.5 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EDO15974.1 - 0.0051 16.7 12.6 1.8 8.8 0.0 7.0 7 0 0 7 7 7 1 Leucine Rich repeat LRR_8 PF13855.1 EDO15974.1 - 0.011 15.4 0.1 0.011 15.4 0.1 5.0 5 1 1 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 EDO15974.1 - 0.012 15.5 7.7 20 5.7 0.0 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 EDO15974.1 - 1.1 9.7 8.8 49 4.7 0.0 6.2 5 1 1 6 6 6 0 Leucine rich repeat Pkinase PF00069.20 EDO15975.1 - 8.6e-73 244.6 0.0 1.1e-72 244.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO15975.1 - 2.8e-33 115.0 0.0 3.9e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO15975.1 - 3.5e-05 22.9 0.0 5.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO15975.1 - 0.043 12.8 0.1 0.085 11.9 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO15975.1 - 0.083 12.6 0.0 0.25 11.0 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family CN_hydrolase PF00795.17 EDO15976.1 - 3.4e-33 114.5 0.0 5.7e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ORMDL PF04061.9 EDO15977.1 - 2.9e-56 188.7 6.5 3.5e-56 188.5 4.5 1.1 1 0 0 1 1 1 1 ORMDL family DUF4271 PF14093.1 EDO15977.1 - 0.0017 18.0 0.3 0.0026 17.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) DctQ PF04290.7 EDO15977.1 - 0.1 12.3 1.2 0.16 11.7 0.9 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Ashwin PF15323.1 EDO15977.1 - 1.5 8.7 6.5 2 8.3 4.5 1.1 1 0 0 1 1 1 0 Developmental protein ACBP PF00887.14 EDO15978.1 - 2.6e-29 100.7 0.3 2.8e-29 100.6 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein HEAT PF02985.17 EDO15979.1 - 1e-15 56.2 15.5 0.00098 19.0 0.1 9.9 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 EDO15979.1 - 3.5e-14 52.7 4.0 7.2e-08 32.6 0.0 8.0 8 1 1 9 9 9 1 HEAT-like repeat HEAT_2 PF13646.1 EDO15979.1 - 1.2e-11 44.7 4.4 1.4e-05 25.2 0.0 6.5 2 1 4 7 7 7 3 HEAT repeats IBN_N PF03810.14 EDO15979.1 - 2.3e-08 33.8 7.9 3.4e-08 33.2 2.9 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EDO15979.1 - 0.0034 16.7 10.6 0.038 13.3 0.0 4.8 5 1 1 6 6 6 1 CLASP N terminal Arm PF00514.18 EDO15979.1 - 0.0044 16.7 3.1 0.15 11.9 0.0 4.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 EDO15979.1 - 0.012 15.5 4.9 1.3 8.9 0.5 4.2 2 2 3 5 5 5 0 Domain of unknown function (DUF3385) DUF3855 PF12967.2 EDO15979.1 - 0.02 14.4 0.5 0.16 11.4 0.0 2.6 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3855) Vac14_Fab1_bd PF12755.2 EDO15979.1 - 0.42 11.0 5.4 3.7 7.9 0.0 4.5 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region TIP120 PF08623.5 EDO15979.1 - 1.3 8.5 11.5 1.5 8.4 0.0 4.4 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) PAP2 PF01569.16 EDO15980.1 - 1.2e-20 73.4 1.2 1.8e-20 72.9 0.7 1.4 1 1 0 1 1 1 1 PAP2 superfamily 6PF2K PF01591.13 EDO15981.1 - 3e-59 199.8 6.6 4.3e-59 199.2 4.6 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDO15981.1 - 6.7e-21 75.0 0.0 2.8e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EDO15981.1 - 0.00049 19.9 0.0 0.00084 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain KOW PF00467.24 EDO15982.1 - 5.6e-05 22.6 3.1 0.00026 20.5 2.2 2.2 1 1 0 1 1 1 1 KOW motif TIM21 PF08294.6 EDO15983.1 - 3.5e-57 192.1 0.0 4.7e-57 191.7 0.0 1.2 1 0 0 1 1 1 1 TIM21 Glucan_synthase PF02364.10 EDO15984.1 - 0 1455.7 0.0 0 1455.1 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EDO15984.1 - 8.9e-40 135.2 0.3 2e-39 134.0 0.2 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Alba PF01918.16 EDO15985.1 - 1.3e-13 50.3 0.9 2e-13 49.6 0.6 1.4 1 0 0 1 1 1 1 Alba DUF3512 PF12024.3 EDO15985.1 - 0.0084 15.4 0.1 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) ParcG PF10274.4 EDO15985.1 - 1.1 9.1 6.2 13 5.6 4.3 2.2 1 1 0 1 1 1 0 Parkin co-regulated protein LAGLIDADG_1 PF00961.14 EDO15985.1 - 2 8.9 12.0 13 6.4 8.3 2.3 1 1 0 1 1 1 0 LAGLIDADG endonuclease WH2 PF02205.15 EDO15986.1 - 1.6e-15 56.1 1.9 1.7e-09 36.9 0.3 4.0 5 0 0 5 5 5 2 WH2 motif MA3 PF02847.12 EDO15987.1 - 2.3e-25 88.4 0.2 1.1e-24 86.2 0.1 2.3 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.14 EDO15987.1 - 2.1e-16 59.9 5.6 2.1e-16 59.9 3.9 2.1 2 0 0 2 2 2 1 MIF4G domain GRASP55_65 PF04495.9 EDO15989.1 - 8.2e-08 32.3 0.1 1.3e-07 31.6 0.1 1.5 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 EDO15989.1 - 0.00042 20.4 0.2 0.00073 19.6 0.2 1.4 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 EDO15989.1 - 0.0032 17.3 0.4 0.0069 16.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain Apolipoprotein PF01442.13 EDO15989.1 - 0.016 14.7 2.6 0.17 11.3 1.8 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Antimicrobial19 PF08225.6 EDO15989.1 - 0.075 12.4 0.1 0.66 9.4 0.0 2.7 2 0 0 2 2 2 0 Pseudin antimicrobial peptide DUF4404 PF14357.1 EDO15989.1 - 0.099 13.0 4.9 0.24 11.8 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Baculo_PEP_C PF04513.7 EDO15989.1 - 0.12 12.2 8.0 1.1 9.1 5.6 2.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlgN PF05130.7 EDO15989.1 - 0.13 12.4 7.2 0.33 11.1 5.0 1.5 1 1 0 1 1 1 0 FlgN protein COG5 PF10392.4 EDO15989.1 - 0.27 11.1 3.8 0.51 10.3 0.2 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF1104 PF06518.6 EDO15989.1 - 1.3 9.2 4.8 1.5 8.9 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) ApoLp-III PF07464.6 EDO15989.1 - 1.6 8.7 6.8 8.4 6.4 0.9 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DNA_primase_lrg PF04104.9 EDO15989.1 - 3.6 6.7 7.3 2.3 7.4 0.8 2.2 1 1 1 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit Thioredoxin PF00085.15 EDO15990.1 - 9.5e-23 79.8 0.2 3.3e-15 55.6 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_8 PF13905.1 EDO15990.1 - 3.5e-06 27.0 2.3 0.089 12.9 0.0 4.7 4 0 0 4 4 4 2 Thioredoxin-like Prominin PF05478.6 EDO15990.1 - 0.11 9.9 3.8 0.066 10.7 1.1 1.6 2 0 0 2 2 2 0 Prominin Prefoldin_2 PF01920.15 EDO15992.1 - 3e-20 71.9 5.0 3.3e-20 71.8 3.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF3010 PF11215.3 EDO15992.1 - 0.062 13.2 1.5 5.1 7.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3010) Peptidase_C25_C PF03785.9 EDO15992.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain DDOST_48kD PF03345.9 EDO15993.1 - 7.9e-139 462.8 9.5 8.9e-139 462.6 6.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta BTB PF00651.26 EDO15994.1 - 3.1e-12 46.4 1.5 3.8e-09 36.5 0.0 3.0 2 1 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 EDO15994.1 - 6.6e-10 39.1 0.1 4.8e-09 36.4 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDO15994.1 - 1.5e-08 34.0 0.7 1.9e-06 27.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EDO15994.1 - 7.5e-07 29.5 0.1 2.5e-06 27.8 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO15994.1 - 2.6e-05 24.0 0.7 0.0039 17.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EDO15994.1 - 0.0015 18.7 2.1 0.031 14.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Hpr_kinase_N PF02603.11 EDO15995.1 - 0.015 15.0 0.0 0.038 13.6 0.0 1.7 1 1 0 1 1 1 0 HPr Serine kinase N terminus RRM_1 PF00076.17 EDO15996.1 - 5e-16 58.0 0.0 7.5e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO15996.1 - 1.1e-11 44.5 0.0 1.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO15996.1 - 4.6e-08 32.8 0.0 6.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EDO15996.1 - 0.0063 16.2 0.0 0.0091 15.7 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nop16 PF09420.5 EDO15997.1 - 8.2e-60 201.6 11.9 9.6e-60 201.4 8.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 GN3L_Grn1 PF08701.6 EDO15998.1 - 2.5e-25 88.1 16.8 6.4e-25 86.8 11.6 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EDO15998.1 - 2.3e-22 79.1 0.1 2.3e-16 59.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO15998.1 - 3.5e-09 36.1 0.1 5.4e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDO15998.1 - 2.8e-06 27.2 0.3 0.25 11.1 0.0 3.6 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EDO15998.1 - 1.6e-05 24.4 0.1 0.029 13.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EDO15998.1 - 0.00027 20.1 0.4 0.00049 19.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EDO15998.1 - 0.00039 19.5 0.1 0.0012 18.0 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 EDO15998.1 - 0.0054 17.2 0.1 0.39 11.2 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EDO15998.1 - 0.018 13.8 0.1 0.042 12.6 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_16 PF13191.1 EDO15998.1 - 0.14 12.1 0.5 0.61 10.0 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EDO15998.1 - 0.68 10.7 2.8 1.1 10.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain CAP_GLY PF01302.20 EDO15999.1 - 4.3e-17 61.5 0.3 8.2e-17 60.6 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EDO15999.1 - 5e-15 54.7 29.4 0.00019 20.9 1.8 5.7 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDO15999.1 - 3e-10 38.6 28.1 0.042 13.8 0.2 9.5 8 1 1 9 9 9 4 Leucine Rich Repeat LRR_8 PF13855.1 EDO15999.1 - 2.2e-09 36.9 23.2 1.1e-06 28.3 3.9 4.5 2 1 3 5 5 5 5 Leucine rich repeat LRR_6 PF13516.1 EDO15999.1 - 6.1e-09 35.0 26.0 0.37 10.9 1.1 8.7 9 0 0 9 9 9 4 Leucine Rich repeat LRR_7 PF13504.1 EDO15999.1 - 0.00049 19.8 22.0 2.6 8.6 0.0 7.8 9 0 0 9 9 9 2 Leucine rich repeat FNIP PF05725.7 EDO15999.1 - 0.0076 16.1 0.7 0.026 14.4 0.5 2.0 1 0 0 1 1 1 1 FNIP Repeat PUA PF01472.15 EDO16000.1 - 8.8e-23 79.8 0.0 1.3e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.5 EDO16000.1 - 0.024 14.3 0.2 0.024 14.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) BSD PF03909.12 EDO16000.1 - 0.1 12.3 0.2 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 BSD domain Trypan_glycop PF00913.14 EDO16000.1 - 0.16 10.8 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) NTF2 PF02136.15 EDO16001.1 - 5.3e-35 120.3 0.3 5.9e-35 120.1 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 EDO16001.1 - 0.004 16.2 0.1 0.0063 15.5 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) DUF4440 PF14534.1 EDO16001.1 - 0.061 13.5 0.0 0.075 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DnaJ-X PF14308.1 EDO16002.1 - 1.8e-62 210.2 4.6 1.8e-62 210.2 3.2 2.5 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EDO16002.1 - 1.2e-23 82.5 2.8 1.2e-23 82.5 2.0 2.4 2 0 0 2 2 2 1 DnaJ domain OPA3 PF07047.7 EDO16002.1 - 0.017 14.8 1.6 0.017 14.8 1.1 2.6 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) SR-25 PF10500.4 EDO16002.1 - 0.23 10.9 18.5 0.6 9.5 12.8 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ycf1 PF05758.7 EDO16002.1 - 0.3 8.7 15.9 0.48 8.0 11.0 1.3 1 0 0 1 1 1 0 Ycf1 DUF3554 PF12074.3 EDO16004.1 - 7.6e-62 209.6 7.7 7.6e-62 209.6 5.4 5.9 5 1 0 5 5 5 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 EDO16004.1 - 6.3e-30 103.3 8.6 2e-09 37.5 0.0 9.9 8 1 1 10 10 10 4 HEAT repeats HEAT PF02985.17 EDO16004.1 - 7e-22 75.4 10.8 0.0073 16.2 0.0 14.2 16 0 0 16 16 16 3 HEAT repeat HEAT_EZ PF13513.1 EDO16004.1 - 9.8e-22 76.8 0.0 0.0078 16.6 0.0 10.1 7 1 4 11 11 11 6 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDO16004.1 - 1.3e-06 28.7 0.2 0.45 10.9 0.0 6.3 6 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region Metallophos PF00149.23 EDO16005.1 - 2.6e-44 151.0 0.1 3.1e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Acid_PPase PF12689.2 EDO16006.1 - 3.7e-42 143.8 0.0 4.2e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase CheW PF01584.14 EDO16006.1 - 0.023 14.1 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 CheW-like domain AAA PF00004.24 EDO16007.1 - 0.032 14.4 0.0 0.098 12.8 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Glyco_transf_22 PF03901.12 EDO16008.1 - 3.8e-65 220.5 40.2 4.6e-65 220.2 27.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CRAL_TRIO PF00650.15 EDO16008.1 - 0.046 13.2 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain CBFD_NFYB_HMF PF00808.18 EDO16009.1 - 3.7e-14 52.5 1.2 6.1e-14 51.8 0.8 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1340 PF07067.6 EDO16009.1 - 0.042 13.0 0.1 0.055 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) RNA_Me_trans PF04252.8 EDO16010.1 - 1.4e-71 239.9 0.0 1.7e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DUF2611 PF11022.3 EDO16011.1 - 1.4e-23 82.7 0.2 1.5e-23 82.6 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) DUF3042 PF11240.3 EDO16011.1 - 0.079 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Cpn10 PF00166.16 EDO16012.1 - 1.8e-26 91.8 0.2 2e-26 91.7 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PRP3 PF08572.5 EDO16013.1 - 1.4e-53 181.5 19.7 3e-53 180.5 13.7 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EDO16013.1 - 6.5e-32 109.9 0.8 6.5e-32 109.9 0.5 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) KSHV_K8 PF07188.6 EDO16013.1 - 0.06 12.5 0.2 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein CAML PF14963.1 EDO16013.1 - 1.1 8.4 4.5 0.17 11.2 0.3 1.7 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand DUF2470 PF10615.4 EDO16015.1 - 0.0091 16.2 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pkinase PF00069.20 EDO16016.1 - 1.2e-75 254.0 0.1 1.2e-75 254.0 0.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16016.1 - 1.2e-36 126.1 0.0 2.2e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EDO16016.1 - 4.5e-16 58.7 1.7 1.5e-15 57.0 1.2 2.0 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EDO16016.1 - 3.3e-11 42.7 0.0 1.2e-10 40.8 0.0 2.0 3 0 0 3 3 3 1 Kinase-like YukC PF10140.4 EDO16016.1 - 0.00049 18.7 0.5 0.00094 17.8 0.3 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EDO16016.1 - 0.00065 19.5 0.3 0.19 11.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDO16016.1 - 0.0084 15.1 0.3 0.016 14.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SIR2 PF02146.12 EDO16017.1 - 7.7e-36 123.4 0.0 2.3e-21 76.3 0.0 2.4 2 0 0 2 2 2 2 Sir2 family IL2 PF00715.12 EDO16017.1 - 0.15 11.7 1.3 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 Interleukin 2 Zn_Tnp_IS1595 PF12760.2 EDO16017.1 - 0.35 10.7 4.5 8.2 6.3 2.6 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EDO16017.1 - 1.5 8.7 5.7 0.72 9.8 1.8 2.1 2 0 0 2 2 2 0 Zinc ribbon domain Rpr2 PF04032.11 EDO16018.1 - 0.027 14.3 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain bZIP_1 PF00170.16 EDO16019.1 - 2.2e-12 46.7 11.3 4.7e-12 45.6 7.8 1.6 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 EDO16019.1 - 0.003 17.2 1.6 0.003 17.2 1.1 1.8 2 0 0 2 2 2 1 Homeobox associated leucine zipper Glutaredoxin2_C PF04399.8 EDO16019.1 - 2.3 7.8 9.0 0.36 10.4 2.1 2.6 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Apc13p PF05839.6 EDO16020.1 - 8.2e-09 35.3 0.0 2.6e-08 33.7 0.0 1.9 2 1 0 2 2 2 1 Apc13p protein PalH PF08733.5 EDO16021.1 - 6.8e-86 288.2 17.8 1e-85 287.6 12.3 1.2 1 0 0 1 1 1 1 PalH/RIM21 LAMTOR PF15454.1 EDO16021.1 - 0.069 13.4 1.0 0.27 11.5 0.1 2.4 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator WW PF00397.21 EDO16021.1 - 0.32 10.9 2.0 1.9 8.4 0.1 2.7 2 0 0 2 2 2 0 WW domain zf-C2H2 PF00096.21 EDO16022.1 - 1.1e-09 38.0 11.7 3.1e-05 24.0 0.3 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO16022.1 - 1e-07 31.8 11.8 0.0001 22.4 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO16022.1 - 5.6e-07 29.4 4.4 0.0067 16.6 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EDO16022.1 - 0.04 13.8 1.4 5.5 7.0 0.2 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-met PF12874.2 EDO16022.1 - 0.61 10.3 3.9 0.91 9.8 0.3 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDO16022.1 - 2.2 8.5 6.4 0.92 9.7 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Fungal_trans PF04082.13 EDO16023.1 - 2.4e-16 59.4 2.5 2.4e-16 59.4 1.8 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO16023.1 - 2.2e-09 37.0 12.7 5.3e-09 35.8 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.9 EDO16025.1 - 9.5e-41 137.1 17.8 5.1e-23 80.3 0.7 2.9 3 0 0 3 3 3 2 PQ loop repeat Steroid_dh PF02544.11 EDO16025.1 - 0.22 11.2 3.9 0.32 10.7 1.1 2.4 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase Snf7 PF03357.16 EDO16026.1 - 2.5e-37 127.8 20.3 3.3e-37 127.5 14.1 1.1 1 0 0 1 1 1 1 Snf7 Mnd1 PF03962.10 EDO16026.1 - 0.0019 17.8 13.0 0.02 14.5 4.8 2.3 1 1 1 2 2 2 1 Mnd1 family YlqD PF11068.3 EDO16026.1 - 0.0023 17.9 11.7 0.0023 17.9 8.1 2.2 1 1 1 2 2 2 1 YlqD protein Fmp27_WPPW PF10359.4 EDO16026.1 - 0.014 13.8 7.3 0.018 13.4 5.1 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tropomyosin_1 PF12718.2 EDO16026.1 - 0.026 14.3 10.4 0.043 13.6 6.8 1.7 1 1 0 1 1 1 0 Tropomyosin like Serine_rich PF08824.5 EDO16026.1 - 0.071 12.8 8.2 0.086 12.5 4.8 1.8 1 1 0 1 1 1 0 Serine rich protein interaction domain Methyltrn_RNA_4 PF09936.4 EDO16026.1 - 0.083 12.3 0.7 0.14 11.6 0.5 1.3 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase Exonuc_VII_L PF02601.10 EDO16026.1 - 0.086 12.0 9.5 0.1 11.7 6.6 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3969 PF13108.1 EDO16026.1 - 0.12 11.9 3.4 0.098 12.3 0.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3969) Atg14 PF10186.4 EDO16026.1 - 0.22 10.4 14.9 0.3 10.0 10.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 EDO16026.1 - 0.36 9.9 6.4 1.3 8.1 4.2 1.8 1 1 0 1 1 1 0 Reovirus sigma C capsid protein COG5 PF10392.4 EDO16026.1 - 0.41 10.6 7.0 0.97 9.3 4.5 1.9 1 1 0 1 1 1 0 Golgi transport complex subunit 5 FliJ PF02050.11 EDO16026.1 - 0.54 10.3 19.9 0.11 12.5 8.6 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein FlaC_arch PF05377.6 EDO16026.1 - 0.86 9.5 6.4 7.1 6.6 0.0 3.6 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Peptidase_S46 PF10459.4 EDO16026.1 - 1.4 7.2 11.5 1.6 7.0 8.0 1.0 1 0 0 1 1 1 0 Peptidase S46 ACR_tran PF00873.14 EDO16026.1 - 1.4 6.2 9.1 2 5.7 6.3 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Cep57_CLD_2 PF14197.1 EDO16026.1 - 1.8 8.5 12.6 0.79 9.7 2.4 3.3 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF4140 PF13600.1 EDO16026.1 - 3.5 8.1 8.1 0.84 10.1 0.4 3.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3584 PF12128.3 EDO16026.1 - 3.7 4.7 19.9 4.6 4.4 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GrpE PF01025.14 EDO16026.1 - 4.3 6.8 10.1 2.4 7.7 5.0 1.9 1 1 1 2 2 2 0 GrpE DUF342 PF03961.8 EDO16026.1 - 4.5 5.5 10.9 2.8 6.2 5.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Laminin_II PF06009.7 EDO16026.1 - 4.5 7.0 11.9 1.6 8.4 4.7 2.1 1 1 1 2 2 2 0 Laminin Domain II CorA PF01544.13 EDO16026.1 - 5 6.0 8.4 26 3.6 5.6 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF972 PF06156.8 EDO16026.1 - 5 7.5 12.9 3.2 8.1 3.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Cep57_MT_bd PF06657.8 EDO16026.1 - 5.1 7.1 11.6 0.51 10.3 3.1 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Seryl_tRNA_N PF02403.17 EDO16026.1 - 7.1 6.6 14.9 2.1 8.4 0.6 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain tRNA-synt_1b PF00579.20 EDO16027.1 - 3.9e-18 65.6 0.0 9.7e-12 44.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) SpoVIF PF14069.1 EDO16027.1 - 0.2 11.4 1.3 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Stage VI sporulation protein F DHBP_synthase PF00926.14 EDO16028.1 - 2.4e-78 261.8 0.0 2.6e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Erv26 PF04148.8 EDO16029.1 - 1.5e-84 282.5 5.3 1.8e-84 282.3 3.7 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF996 PF06195.8 EDO16029.1 - 0.0012 18.8 1.9 0.0024 17.8 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF996) Cytochrom_C_asm PF01578.15 EDO16029.1 - 0.53 9.8 6.2 0.2 11.2 1.2 2.4 1 1 1 3 3 3 0 Cytochrome C assembly protein NAD_binding_2 PF03446.10 EDO16030.1 - 1.8e-53 180.6 0.0 2.2e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 6PGD PF00393.14 EDO16030.1 - 4.3e-15 55.7 0.8 6e-15 55.2 0.5 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain F420_oxidored PF03807.12 EDO16030.1 - 0.0042 17.4 0.0 0.0072 16.7 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 EDO16030.1 - 0.035 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF433 PF04255.9 EDO16030.1 - 0.11 11.9 0.0 0.36 10.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF433) 6PGD PF00393.14 EDO16031.1 - 1e-108 362.9 0.0 1.1e-108 362.8 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain Mito_carr PF00153.22 EDO16032.1 - 7.7e-66 217.8 0.0 2.6e-23 81.5 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein CCDC84 PF14968.1 EDO16032.1 - 0.019 14.4 0.6 0.031 13.8 0.4 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 Eapp_C PF10238.4 EDO16033.1 - 0.015 15.2 9.5 1.6 8.6 6.0 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein Tim54 PF11711.3 EDO16033.1 - 0.13 10.8 2.1 0.19 10.3 1.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Tetraspannin PF00335.15 EDO16033.1 - 3.6 6.8 6.2 6.5 5.9 4.3 1.4 1 0 0 1 1 1 0 Tetraspanin family Pex14_N PF04695.8 EDO16033.1 - 5.8 6.9 9.9 13 5.8 6.9 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MFS_1 PF07690.11 EDO16034.1 - 1.8e-33 115.6 24.2 2.6e-33 115.1 16.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Gpi16 PF04113.9 EDO16035.1 - 1.2e-181 604.6 0.1 1.7e-181 604.1 0.1 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component HEAT_2 PF13646.1 EDO16036.1 - 1.7e-17 63.4 0.0 0.001 19.3 0.0 7.3 5 2 3 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 EDO16036.1 - 4.7e-17 61.9 0.0 0.069 13.6 0.0 7.9 8 0 0 8 8 8 4 HEAT-like repeat HEAT PF02985.17 EDO16036.1 - 5.5e-16 57.1 13.8 0.056 13.5 0.0 10.5 13 0 0 13 13 13 4 HEAT repeat Vac14_Fab1_bd PF12755.2 EDO16036.1 - 3.4e-08 33.7 0.4 0.03 14.7 0.0 5.8 4 2 4 8 8 8 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EDO16036.1 - 5.3e-08 31.6 5.8 0.0052 15.1 0.0 3.6 3 1 0 3 3 3 2 Adaptin N terminal region Arm PF00514.18 EDO16036.1 - 8.4e-06 25.4 3.7 4.2 7.3 0.0 6.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EDO16036.1 - 4.1e-05 23.0 1.8 1.5 8.0 0.0 5.9 4 2 3 7 7 7 1 CLASP N terminal MMS19_N PF14500.1 EDO16036.1 - 0.0012 18.1 0.2 0.15 11.2 0.1 3.6 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.2 EDO16036.1 - 0.019 14.8 5.0 10 5.8 0.0 5.0 6 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EDO16036.1 - 0.053 11.7 3.2 0.79 7.9 0.3 3.7 3 2 0 4 4 4 0 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 EDO16037.1 - 1e-84 284.7 8.3 1.2e-84 284.4 5.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EDO16037.1 - 1.1e-11 44.9 0.1 2.7e-08 33.9 0.0 4.2 5 1 1 6 6 6 1 HEAT repeats Cnd1 PF12717.2 EDO16037.1 - 1.8e-08 34.4 1.1 2e-06 27.8 0.0 3.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EDO16037.1 - 2.2e-07 30.3 1.8 0.071 13.2 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 EDO16037.1 - 3.5e-05 24.1 0.5 0.45 11.0 0.0 3.9 2 1 2 4 4 4 3 HEAT-like repeat Prp18 PF02840.10 EDO16037.1 - 0.0059 16.4 0.9 0.057 13.2 0.1 2.5 2 0 0 2 2 2 1 Prp18 domain DDE_Tnp_IS66_C PF13817.1 EDO16037.1 - 0.0091 15.9 0.0 0.12 12.3 0.0 2.7 2 0 0 2 2 2 1 IS66 C-terminal element RasGEF_N_2 PF14663.1 EDO16037.1 - 0.025 14.4 3.3 1.7 8.6 0.1 3.4 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vac14_Fab1_bd PF12755.2 EDO16037.1 - 0.089 13.1 0.7 3.1 8.2 0.0 3.0 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Aminotran_4 PF01063.14 EDO16038.1 - 1.3e-23 83.7 0.0 2.8e-23 82.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class IV Kdo PF06293.9 EDO16039.1 - 3.4e-06 26.2 0.0 6.2e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO16039.1 - 0.0033 17.1 0.1 0.022 14.5 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EDO16039.1 - 0.0045 16.1 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF1679 PF07914.6 EDO16039.1 - 0.017 13.8 0.0 0.034 12.8 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1679) FMO-like PF00743.14 EDO16039.1 - 0.088 10.9 0.0 0.24 9.5 0.0 1.6 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like DUF2424 PF10340.4 EDO16040.1 - 5.7e-170 564.9 6.1 6.4e-170 564.7 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EDO16040.1 - 1.9e-13 50.4 0.0 5.2e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EDO16040.1 - 0.00048 18.9 0.0 0.099 11.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EDO16040.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family tRNA-synt_1g PF09334.6 EDO16041.1 - 1.7e-147 491.1 0.3 2.2e-147 490.8 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 EDO16041.1 - 5.7e-24 84.8 0.1 1.5e-23 83.4 0.1 1.8 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1 PF00133.17 EDO16041.1 - 2.7e-10 38.8 2.1 0.00039 18.5 0.0 3.3 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDO16041.1 - 0.026 14.2 0.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Pkinase PF00069.20 EDO16042.1 - 1.5e-46 158.6 2.8 1.1e-45 155.7 1.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16042.1 - 5.9e-23 81.2 0.1 8e-20 70.9 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase GTP_cyclohydroI PF01227.17 EDO16043.1 - 1.8e-74 248.8 0.2 2.1e-74 248.6 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EDO16043.1 - 7.8e-05 22.5 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 QueF-like protein Got1 PF04178.7 EDO16044.1 - 4.6e-15 55.7 6.2 5e-15 55.6 4.3 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 EDO16044.1 - 0.0097 14.9 8.9 0.019 13.9 6.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF973) ATP1G1_PLM_MAT8 PF02038.11 EDO16044.1 - 1.2 8.2 8.5 4.9 6.2 1.0 2.4 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF308 PF03729.8 EDO16044.1 - 1.4 9.0 14.4 4.6 7.3 0.2 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF872 PF05915.7 EDO16044.1 - 3 7.7 6.1 5.7 6.8 3.9 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) PEMT PF04191.8 EDO16044.1 - 3.8 7.6 7.8 3.3 7.8 2.5 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase Amidase PF01425.16 EDO16045.1 - 1.8e-116 389.6 0.0 2.1e-116 389.3 0.0 1.0 1 0 0 1 1 1 1 Amidase MDM31_MDM32 PF08118.6 EDO16046.1 - 1.4e-238 792.4 9.9 1.6e-238 792.1 6.9 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins RNA_pol_A_bac PF01000.21 EDO16047.1 - 0.12 12.4 2.7 0.3 11.2 0.9 2.4 3 1 0 3 3 3 0 RNA polymerase Rpb3/RpoA insert domain TMEM51 PF15345.1 EDO16047.1 - 8.6 5.9 13.8 14 5.3 9.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 IBN_N PF03810.14 EDO16048.1 - 5e-19 67.9 0.1 7.8e-17 60.9 0.0 3.6 3 0 0 3 3 3 2 Importin-beta N-terminal domain TMF_TATA_bd PF12325.3 EDO16050.1 - 3.1e-35 120.5 19.5 3.1e-35 120.5 13.5 5.7 3 2 2 5 5 5 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EDO16050.1 - 2.5e-16 59.2 7.9 2.5e-16 59.2 5.5 9.3 5 3 4 9 9 9 1 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EDO16050.1 - 0.0076 15.8 15.8 0.0076 15.8 10.9 5.2 2 2 3 5 5 5 2 IncA protein Lzipper-MIP1 PF14389.1 EDO16050.1 - 1.8 8.7 50.0 0.44 10.6 1.6 8.0 4 3 2 8 8 8 0 Leucine-zipper of ternary complex factor MIP1 ATG16 PF08614.6 EDO16050.1 - 8.9 6.0 79.0 0.047 13.5 6.2 5.2 3 2 3 6 6 6 0 Autophagy protein 16 (ATG16) Mito_carr PF00153.22 EDO16051.1 - 2.1e-16 59.3 1.1 2.9e-13 49.3 0.1 3.3 4 0 0 4 4 4 2 Mitochondrial carrier protein Pro_isomerase PF00160.16 EDO16052.1 - 2.2e-41 141.6 0.1 3.4e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EDO16052.1 - 6.5e-13 48.1 4.2 4.3e-06 26.2 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDO16052.1 - 1.9e-10 39.8 8.9 6.4e-06 25.6 1.5 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO16052.1 - 1.4e-09 37.1 15.3 1.2e-07 30.9 2.4 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO16052.1 - 1.6e-06 27.9 1.9 0.0012 18.7 0.7 2.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO16052.1 - 7.4e-05 22.2 19.0 0.0012 18.5 1.2 4.6 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO16052.1 - 0.0062 17.1 0.0 0.19 12.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO16052.1 - 0.013 15.9 2.1 0.52 10.8 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDO16052.1 - 0.024 14.4 0.0 0.094 12.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EDO16052.1 - 0.054 13.7 2.6 0.46 10.8 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDO16052.1 - 0.3 11.0 2.2 25 4.9 0.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EDO16052.1 - 1.3 9.2 8.1 7.3 6.8 5.1 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Rav1p_C PF12234.3 EDO16053.1 - 8.7e-279 926.0 1.1 8.7e-279 926.0 0.8 2.0 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.27 EDO16053.1 - 0.00033 20.4 1.3 4 7.4 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Pet191_N PF10203.4 EDO16054.1 - 1e-26 92.7 3.8 1.4e-26 92.2 2.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EDO16054.1 - 0.084 12.6 0.6 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EDO16054.1 - 0.2 11.6 5.2 0.35 10.8 0.3 2.7 3 0 0 3 3 3 0 CHCH domain SNF2_N PF00176.18 EDO16055.1 - 2.7e-76 256.2 0.9 3.8e-76 255.7 0.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO16055.1 - 2.7e-15 55.9 0.0 8.9e-15 54.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2235 PF09994.4 EDO16056.1 - 2.4e-80 269.8 0.0 3.3e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Herpes_UL52 PF03121.10 EDO16056.1 - 0.052 13.2 1.0 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase HECT PF00632.20 EDO16057.1 - 4e-86 289.0 2.1 4e-86 289.0 1.5 2.4 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) Ribosomal_L7Ae PF01248.21 EDO16058.1 - 1.1e-26 92.1 0.1 1.3e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDO16058.1 - 0.012 15.4 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 PELOTA_1 PF15608.1 EDO16058.1 - 0.064 13.0 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain Voltage_CLC PF00654.15 EDO16059.1 - 3e-78 263.3 26.0 3e-78 263.3 18.0 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EDO16059.1 - 2.9e-11 42.9 0.0 6.6e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain ATP-synt_C PF00137.16 EDO16060.1 - 4.1e-32 109.8 28.6 8.9e-19 67.1 7.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EDO16060.1 - 0.91 9.0 4.5 0.26 10.8 0.9 1.6 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A CDC27 PF09507.5 EDO16061.1 - 3.3e-09 36.5 38.5 3.6e-09 36.3 25.9 1.5 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 UCH PF00443.24 EDO16062.1 - 1.9e-52 178.0 1.6 1.9e-52 178.0 1.1 3.1 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EDO16062.1 - 1.8e-22 78.4 8.4 2.6e-16 58.7 0.3 4.0 4 0 0 4 4 4 2 A repeated domain in UCH-protein UCH_1 PF13423.1 EDO16062.1 - 1.2e-10 41.3 6.5 1.7e-06 27.6 0.8 4.6 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Sec23_helical PF04815.10 EDO16062.1 - 0.0043 16.4 0.3 0.025 14.0 0.2 2.3 1 0 0 1 1 1 1 Sec23/Sec24 helical domain GPP34 PF05719.6 EDO16063.1 - 5.6e-61 206.1 0.0 7e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) YCII PF03795.9 EDO16064.1 - 1.4e-08 34.7 0.0 1.7e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.9 EDO16065.1 - 1.5e-06 28.3 0.0 1.8e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain FHA PF00498.21 EDO16066.1 - 0.00014 21.9 0.3 0.00054 20.0 0.1 2.1 2 0 0 2 2 2 1 FHA domain TLD PF07534.11 EDO16067.1 - 5e-28 97.8 0.1 6.4e-27 94.2 0.1 2.2 2 0 0 2 2 2 1 TLD NUC153 PF08159.7 EDO16068.1 - 3.4e-14 52.1 16.6 3.9e-14 51.9 2.6 3.1 3 0 0 3 3 3 2 NUC153 domain RNA_pol_Rpb1_5 PF04998.12 EDO16069.1 - 6.8e-98 327.3 0.2 1.1e-97 326.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EDO16069.1 - 2.5e-83 280.1 0.0 4.3e-83 279.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EDO16069.1 - 4.2e-70 234.9 0.2 1.6e-69 233.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EDO16069.1 - 4.2e-39 133.7 0.0 1.1e-38 132.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EDO16069.1 - 4.5e-31 106.7 0.0 1.5e-30 105.1 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF2786 PF10979.3 EDO16069.1 - 0.11 12.1 0.2 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Peptidase_M18 PF02127.10 EDO16070.1 - 1.1e-176 587.6 0.0 1.2e-176 587.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EDO16070.1 - 3.3e-08 32.6 0.0 7.4e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase WD40 PF00400.27 EDO16071.1 - 1.7e-38 129.1 9.7 3.5e-09 36.1 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat GATA PF00320.22 EDO16072.1 - 7.8e-15 53.9 2.7 1.5e-14 53.0 1.9 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EDO16072.1 - 0.0079 15.5 0.2 0.016 14.4 0.1 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding K_channel_TID PF07941.6 EDO16072.1 - 0.25 11.6 2.7 0.59 10.3 1.9 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain PHD PF00628.24 EDO16073.1 - 1.8e-10 40.3 9.1 4.1e-10 39.1 6.3 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EDO16073.1 - 5.1e-06 26.8 0.0 5.1e-06 26.8 0.0 3.6 4 1 0 4 4 4 1 SET domain PHD_2 PF13831.1 EDO16073.1 - 0.0058 15.9 4.5 0.012 14.9 3.1 1.5 1 0 0 1 1 1 1 PHD-finger DEAD PF00270.24 EDO16074.1 - 2.2e-38 131.3 0.1 4.2e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO16074.1 - 1.6e-18 66.3 0.0 4e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EDO16074.1 - 1.3e-17 63.1 0.1 3e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EDO16074.1 - 7.9e-05 22.5 1.7 0.00014 21.8 0.0 2.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDO16074.1 - 0.092 12.8 1.9 1.3 9.1 0.5 3.1 2 1 0 2 2 2 0 AAA domain IF-2B PF01008.12 EDO16075.1 - 2.7e-71 239.8 0.0 3.1e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 EDO16075.1 - 0.021 14.4 0.0 6.9 6.2 0.0 2.4 2 0 0 2 2 2 0 DeoR C terminal sensor domain PTPLA PF04387.9 EDO16076.1 - 2.4e-49 166.9 6.4 4.3e-49 166.0 4.4 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA BRCT PF00533.21 EDO16077.1 - 9.6e-18 64.1 21.3 3.5e-08 33.4 0.1 5.6 4 2 1 5 5 5 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EDO16077.1 - 5.2e-10 39.0 0.6 1.7e-05 24.5 0.0 4.1 3 1 0 3 3 3 3 twin BRCT domain Zn_clus PF00172.13 EDO16078.1 - 9.7e-11 41.3 10.3 1.9e-10 40.4 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OTCace PF00185.19 EDO16079.1 - 7.5e-44 149.3 0.4 1.1e-43 148.7 0.3 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 EDO16079.1 - 1.5e-40 138.1 0.0 2.3e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain BTB PF00651.26 EDO16079.1 - 0.06 13.3 0.2 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 BTB/POZ domain Vps51 PF08700.6 EDO16080.1 - 7.3e-11 41.7 2.7 7.3e-11 41.7 1.9 1.8 2 0 0 2 2 2 1 Vps51/Vps67 HBS1_N PF08938.5 EDO16080.1 - 0.042 13.9 0.7 0.1 12.6 0.5 1.7 1 0 0 1 1 1 0 HBS1 N-terminus EF-hand_4 PF12763.2 EDO16081.1 - 0.00017 21.2 0.2 0.00081 19.0 0.1 2.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Iron_traffic PF04362.9 EDO16081.1 - 0.27 10.6 3.1 0.13 11.6 0.2 1.9 2 0 0 2 2 2 0 Bacterial Fe(2+) trafficking Ras PF00071.17 EDO16082.1 - 2.1e-56 189.7 0.4 2.5e-56 189.5 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO16082.1 - 1.1e-21 77.4 0.1 1.8e-21 76.8 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO16082.1 - 8.2e-15 54.4 0.1 1.1e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDO16082.1 - 1.6e-07 30.6 0.2 2.6e-07 30.0 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO16082.1 - 1.1e-06 28.2 0.0 2.2e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO16082.1 - 0.00012 21.9 0.0 0.00024 21.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDO16082.1 - 0.039 13.1 0.2 0.37 9.9 0.0 2.2 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDO16082.1 - 0.05 13.5 0.1 0.092 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain KH_1 PF00013.24 EDO16083.1 - 3.9e-59 196.1 41.1 4.9e-14 51.7 2.2 11.4 11 0 0 11 11 11 9 KH domain KH_3 PF13014.1 EDO16083.1 - 7.9e-35 117.9 37.3 7.8e-08 31.8 0.8 10.3 9 0 0 9 9 9 8 KH domain KH_2 PF07650.12 EDO16083.1 - 5.6e-09 35.4 21.7 9.1e-06 25.1 0.1 7.5 6 2 1 7 7 7 3 KH domain KH_4 PF13083.1 EDO16083.1 - 0.00046 19.7 2.9 0.61 9.7 0.0 5.7 5 0 0 5 5 5 1 KH domain BMC PF00936.14 EDO16083.1 - 0.058 13.0 0.1 6 6.6 0.0 3.5 4 0 0 4 4 4 0 BMC domain CAP PF00188.21 EDO16084.1 - 4.6e-19 69.1 8.0 4.6e-19 69.1 5.5 1.8 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Lipase_chap PF03280.9 EDO16084.1 - 2.1 7.8 8.1 3.1 7.2 5.6 1.1 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein TFIIA PF03153.8 EDO16084.1 - 3.9 7.2 12.7 4.5 7.0 8.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cytokin_check_N PF10407.4 EDO16086.1 - 3.6e-29 100.2 5.3 3.6e-29 100.2 3.7 2.9 3 0 0 3 3 3 1 Cdc14 phosphatase binding protein N-terminus FtsJ PF01728.14 EDO16087.1 - 0.35 10.8 2.4 3.7 7.4 1.7 2.2 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF4458 PF14660.1 EDO16087.1 - 1.3 9.0 6.6 1.7 8.6 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4458) DUF626 PF04776.7 EDO16088.1 - 0.02 15.2 0.2 0.023 15.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF626) zf-H2C2_2 PF13465.1 EDO16089.1 - 5.5e-06 26.4 9.0 0.00013 22.0 3.0 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EDO16089.1 - 0.0013 18.9 13.2 0.073 13.4 2.7 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO16089.1 - 0.019 15.2 15.5 0.047 14.0 1.9 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger ENTH PF01417.15 EDO16090.1 - 3.6e-46 156.0 0.4 3.6e-46 156.0 0.3 2.0 3 0 0 3 3 3 1 ENTH domain ANTH PF07651.11 EDO16090.1 - 0.00055 18.7 0.0 0.00095 17.9 0.0 1.4 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 EDO16090.1 - 0.026 14.1 0.1 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 VHS domain Zn_clus PF00172.13 EDO16091.1 - 0.0041 16.9 8.1 0.0088 15.9 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMG-CoA_red PF00368.13 EDO16092.1 - 1.3e-155 517.6 0.7 1.7e-155 517.2 0.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EDO16092.1 - 2.5e-44 150.6 0.9 5.5e-44 149.5 0.6 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EDO16092.1 - 2.9e-07 30.0 8.1 2.9e-07 30.0 5.6 2.5 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation Ribosomal_L6e PF01159.14 EDO16093.1 - 1.7e-39 134.3 2.7 2.4e-39 133.9 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e C2 PF00168.25 EDO16094.1 - 8.2e-54 179.4 2.5 8.7e-19 67.1 0.0 5.4 5 0 0 5 5 5 5 C2 domain Dor1 PF04124.7 EDO16095.1 - 1.9e-35 121.9 6.6 1.4e-34 119.0 4.6 2.1 1 1 0 1 1 1 1 Dor1-like family Mitofilin PF09731.4 EDO16095.1 - 0.00097 17.9 21.1 0.00097 17.9 14.6 2.2 2 0 0 2 2 2 1 Mitochondrial inner membrane protein Apc3 PF12895.2 EDO16095.1 - 0.021 14.9 0.0 0.097 12.8 0.0 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EDO16095.1 - 0.038 13.6 0.8 0.93 9.1 0.2 2.5 2 0 0 2 2 2 0 TPR repeat COPIIcoated_ERV PF07970.7 EDO16097.1 - 4.6e-33 114.7 0.0 6.8e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EDO16097.1 - 2.3e-20 72.3 0.0 4e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Oxidored_q1_N PF00662.15 EDO16098.1 - 0.032 13.7 0.4 0.11 12.0 0.3 1.9 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF912 PF06024.7 EDO16098.1 - 0.065 13.2 1.9 0.16 11.9 0.6 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2231 PF09990.4 EDO16098.1 - 0.078 13.3 2.6 1.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) MLANA PF14991.1 EDO16098.1 - 4 7.4 4.7 1 9.4 0.1 2.3 3 0 0 3 3 3 0 Protein melan-A AAA PF00004.24 EDO16099.1 - 8.9e-19 68.0 0.1 6.4e-18 65.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 EDO16099.1 - 8.8e-08 31.9 0.1 2.3e-07 30.5 0.1 1.8 1 0 0 1 1 1 1 BAH domain AAA_16 PF13191.1 EDO16099.1 - 9.6e-08 32.2 0.0 5.8e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO16099.1 - 9.7e-06 25.7 0.0 9.4e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EDO16099.1 - 0.0056 16.3 0.0 0.014 15.0 0.0 1.7 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EDO16099.1 - 0.042 14.0 0.0 0.6 10.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 EDO16099.1 - 0.38 11.5 0.0 0.38 11.5 0.0 3.7 3 2 0 3 3 3 0 AAA domain Ribosomal_S3Ae PF01015.13 EDO16100.1 - 3.4e-80 267.9 7.6 4e-80 267.7 5.2 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EDO16100.1 - 0.023 14.0 0.0 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region PIF1 PF05970.9 EDO16101.1 - 1.1e-74 251.6 1.7 4.4e-55 187.1 0.3 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EDO16101.1 - 7.2e-12 45.3 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO16101.1 - 3.1e-07 30.6 0.0 1.1e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO16101.1 - 0.0013 18.4 0.1 0.0026 17.4 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EDO16101.1 - 0.0022 18.1 0.0 0.012 15.6 0.0 2.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain RNA_helicase PF00910.17 EDO16101.1 - 0.0026 17.8 0.1 0.025 14.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_11 PF13086.1 EDO16101.1 - 0.0038 16.8 1.4 0.92 9.0 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_32 PF13654.1 EDO16101.1 - 0.0049 15.5 0.3 0.013 14.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDO16101.1 - 0.014 15.0 0.0 0.043 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 EDO16101.1 - 0.015 14.5 0.4 0.077 12.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein TrwB_AAD_bind PF10412.4 EDO16101.1 - 0.02 13.5 0.1 0.038 12.6 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 EDO16101.1 - 0.021 13.8 0.1 0.021 13.8 0.1 2.4 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EDO16101.1 - 0.027 14.6 0.0 0.12 12.6 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EDO16101.1 - 0.036 12.9 0.1 0.064 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_RecD PF05127.9 EDO16101.1 - 0.044 13.4 0.2 0.21 11.2 0.1 2.1 1 1 0 1 1 1 0 Helicase Mg_chelatase PF01078.16 EDO16101.1 - 0.091 11.9 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EDO16101.1 - 0.092 12.7 0.1 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF104 PF01954.11 EDO16101.1 - 0.12 12.3 3.2 0.26 11.3 0.2 3.2 2 0 0 2 2 2 0 Protein of unknown function DUF104 OGG_N PF07934.7 EDO16102.1 - 6.9e-20 71.1 0.5 1.8e-19 69.7 0.1 1.9 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EDO16102.1 - 4.3e-19 68.8 0.0 7.4e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein MRP-L47 PF06984.8 EDO16103.1 - 2.3e-24 85.1 0.9 5e-24 84.0 0.6 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF2884 PF11101.3 EDO16103.1 - 0.019 14.3 0.6 0.041 13.2 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) DUF2984 PF11203.3 EDO16103.1 - 0.055 13.5 0.3 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) DUF883 PF05957.8 EDO16103.1 - 0.1 13.0 1.8 0.23 11.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) LSM PF01423.17 EDO16104.1 - 3e-17 61.8 0.2 3.8e-17 61.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO16104.1 - 0.048 13.5 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain SH3_9 PF14604.1 EDO16104.1 - 0.081 12.5 0.1 0.99 9.0 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain cNMP_binding PF00027.24 EDO16105.1 - 4.5e-20 71.2 0.0 1.6e-18 66.3 0.0 2.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Patatin PF01734.17 EDO16105.1 - 2.9e-19 69.7 0.3 8.9e-12 45.3 0.2 2.5 2 0 0 2 2 2 2 Patatin-like phospholipase cNMP_binding PF00027.24 EDO16106.1 - 4.1e-07 29.7 0.1 0.41 10.4 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Hid1 PF12722.2 EDO16107.1 - 1.9e-286 952.4 58.2 2.4e-286 952.1 40.3 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EDO16107.1 - 4.1e-09 35.1 30.6 4.1e-09 35.1 21.2 2.4 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein WGG PF10273.4 EDO16108.1 - 1.2e-30 105.3 0.6 2.3e-30 104.4 0.1 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 EGL-1 PF11430.3 EDO16108.1 - 0.031 13.8 0.3 8.2 6.1 0.0 2.6 2 0 0 2 2 2 0 Programmed cell death activator EGL-1 Metallophos PF00149.23 EDO16109.1 - 3.8e-42 143.9 0.6 5.5e-42 143.4 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IMPDH PF00478.20 EDO16110.1 - 1.2e-128 428.9 3.6 1.3e-128 428.7 2.5 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EDO16110.1 - 2.7e-14 52.6 0.0 1e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EDO16110.1 - 4.4e-09 35.9 2.0 5.6e-05 22.4 0.9 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EDO16110.1 - 1.3e-06 27.5 0.7 3.5e-06 26.0 0.5 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EDO16110.1 - 0.0033 16.7 0.4 0.011 14.9 0.3 1.8 1 1 0 1 1 1 1 Histidine biosynthesis protein DUF1900 PF08954.6 EDO16111.1 - 6.3e-48 161.7 0.0 1.2e-47 160.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EDO16111.1 - 8.8e-32 108.5 0.4 1.6e-31 107.7 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EDO16111.1 - 2e-24 84.5 4.0 6.5e-08 32.1 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EDO16111.1 - 1.4e-08 33.3 0.4 0.00013 20.2 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EDO16111.1 - 0.0014 18.3 0.8 0.085 12.5 0.0 2.9 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A zf-RING_2 PF13639.1 EDO16112.1 - 2.2e-06 27.3 8.4 3.9e-06 26.5 5.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDO16112.1 - 6.4e-06 26.0 10.1 1.6e-05 24.8 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO16112.1 - 7.3e-06 25.6 8.5 1.6e-05 24.5 5.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO16112.1 - 9.9e-06 25.1 9.4 2.6e-05 23.7 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO16112.1 - 4e-05 23.2 7.6 8.6e-05 22.1 5.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO16112.1 - 0.00031 20.3 4.9 0.0011 18.6 3.4 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDO16112.1 - 0.063 13.1 11.2 0.029 14.2 5.1 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EDO16112.1 - 0.87 9.1 7.1 2.4 7.7 4.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PH PF00169.24 EDO16113.1 - 9.1e-10 38.6 1.0 3.3e-09 36.8 0.0 2.6 3 0 0 3 3 3 1 PH domain RhoGEF PF00621.15 EDO16113.1 - 4.9e-09 36.3 1.8 6.3e-09 35.9 0.1 2.1 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 EDO16113.1 - 1.2e-07 31.7 3.9 8.1e-06 25.8 0.3 3.5 2 1 0 2 2 2 1 Pleckstrin homology domain LRR_4 PF12799.2 EDO16114.1 - 1.1e-37 127.0 52.6 8.3e-10 38.0 3.7 7.5 2 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO16114.1 - 1e-24 86.0 39.8 6.9e-11 41.7 1.0 6.0 1 1 5 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 EDO16114.1 - 3e-13 47.8 39.3 0.04 13.9 0.4 11.0 11 0 0 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.1 EDO16114.1 - 7.1e-09 34.8 35.0 0.62 10.2 0.0 10.8 7 3 4 11 11 11 4 Leucine Rich repeat LRR_9 PF14580.1 EDO16114.1 - 3.2e-08 33.3 19.3 6.7e-05 22.5 2.1 3.7 1 1 1 3 3 3 3 Leucine-rich repeat LRR_7 PF13504.1 EDO16114.1 - 1.4e-07 30.5 17.3 1.7 9.1 0.1 9.1 9 1 0 9 9 9 3 Leucine rich repeat Latarcin PF10279.4 EDO16114.1 - 0.2 11.8 3.4 42 4.4 2.4 3.8 1 1 0 1 1 1 0 Latarcin precursor Tex_N PF09371.5 EDO16114.1 - 0.85 8.9 5.9 3 7.1 0.4 3.6 3 1 0 3 3 3 0 Tex-like protein N-terminal domain DUF3744 PF12558.3 EDO16114.1 - 4.9 7.6 14.9 12 6.4 2.7 4.4 2 2 3 5 5 5 0 ATP-binding cassette cobalt transporter Amidohydro_2 PF04909.9 EDO16115.1 - 1.6e-06 27.9 0.0 3.7e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EDO16115.1 - 1.7e-06 28.3 0.0 3.1e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase Mo25 PF08569.6 EDO16116.1 - 1.2e-10 40.9 0.0 1.3e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 Mo25-like Mtr2 PF10429.4 EDO16117.1 - 6.8e-70 234.1 0.1 7.9e-70 233.9 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 Pribosyl_synth PF14572.1 EDO16118.1 - 5.2e-39 133.8 0.3 1.3e-29 103.2 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EDO16118.1 - 4e-37 126.5 0.1 1.2e-36 124.9 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EDO16118.1 - 2.1e-05 24.2 0.0 0.02 14.5 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl transferase domain DUF4050 PF13259.1 EDO16119.1 - 2.6e-23 82.2 0.8 4.9e-23 81.3 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Ribosomal_L7Ae PF01248.21 EDO16120.1 - 4.3e-23 80.6 0.3 6.7e-23 80.0 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EDO16120.1 - 0.00074 19.3 0.1 0.0018 18.1 0.1 1.8 1 1 0 1 1 1 1 RNase P subunit Pop3 FGGY_C PF02782.11 EDO16121.1 - 5.3e-75 251.3 0.3 7.9e-75 250.8 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EDO16121.1 - 1.3e-45 155.6 0.2 4.7e-37 127.6 0.0 2.8 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Autophagy_act_C PF03987.10 EDO16122.1 - 1.1e-05 25.5 0.6 8.4e-05 22.6 0.4 2.3 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Fer2_3 PF13085.1 EDO16123.1 - 5.7e-33 113.0 0.1 9.3e-33 112.3 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EDO16123.1 - 2.1e-10 40.7 7.0 2.1e-10 40.7 4.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EDO16123.1 - 5.3e-09 35.9 5.3 5.3e-09 35.9 3.7 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EDO16123.1 - 8.8e-06 26.0 1.9 8.8e-06 26.0 1.3 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EDO16123.1 - 9.6e-05 22.1 4.7 9.6e-05 22.1 3.3 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EDO16123.1 - 0.00011 22.3 6.7 0.026 14.7 0.4 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 EDO16123.1 - 0.00019 21.0 3.7 0.0088 15.7 0.6 2.4 2 0 0 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EDO16123.1 - 0.0015 18.8 5.6 0.0015 18.8 3.9 2.8 2 2 1 3 3 3 1 4Fe-4S dicluster domain Fer4_15 PF13459.1 EDO16123.1 - 4.7 7.8 8.4 1.4 9.4 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain Ecm29 PF13001.2 EDO16124.1 - 4.9e-149 497.0 15.1 1.9e-147 491.7 2.1 4.1 4 0 0 4 4 4 3 Proteasome stabiliser HEAT PF02985.17 EDO16124.1 - 7.6e-13 47.3 9.5 0.055 13.5 0.0 8.9 10 0 0 10 10 10 4 HEAT repeat Vac14_Fab1_bd PF12755.2 EDO16124.1 - 1.1e-06 28.9 0.2 0.028 14.7 0.0 5.7 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EDO16124.1 - 0.0027 18.1 0.1 1.6e+02 2.9 0.0 6.2 6 0 0 6 6 6 0 HEAT-like repeat Antimicrobial_4 PF08024.6 EDO16124.1 - 0.27 11.1 1.5 0.97 9.3 1.0 1.9 1 0 0 1 1 1 0 Ant antimicrobial peptide ubiquitin PF00240.18 EDO16125.1 - 2.3e-235 760.5 47.0 2.6e-33 113.2 0.6 7.0 7 0 0 7 7 7 7 Ubiquitin family Rad60-SLD PF11976.3 EDO16125.1 - 1.7e-134 437.7 43.0 1e-18 66.7 0.5 7.0 7 0 0 7 7 7 7 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDO16125.1 - 1e-39 134.6 24.9 0.00035 20.7 0.1 9.2 7 7 0 7 7 7 7 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDO16125.1 - 4.9e-36 123.8 7.2 0.002 17.8 0.0 7.0 7 0 0 7 7 7 7 Telomere stability and silencing DUF2407 PF10302.4 EDO16125.1 - 5e-22 77.9 9.7 0.28 11.3 0.0 7.2 1 1 5 7 7 7 7 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EDO16125.1 - 2e-21 75.9 12.4 0.3 11.0 0.0 8.0 7 0 0 7 7 7 7 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EDO16125.1 - 2.6e-18 65.8 0.0 3.1 7.8 0.0 7.9 7 0 0 7 7 7 7 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EDO16125.1 - 5.2e-09 35.8 16.2 10 6.1 0.0 7.2 7 0 0 7 7 7 0 GLUT4 regulating protein TUG FlgD_ig PF13860.1 EDO16125.1 - 1.7e-06 27.6 14.9 28 4.5 0.0 7.2 7 0 0 7 7 7 0 FlgD Ig-like domain Big_3_3 PF13750.1 EDO16125.1 - 3.5e-06 26.5 0.1 1e+02 2.3 0.0 6.5 7 0 0 7 7 7 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 EDO16125.1 - 6.2e-05 23.2 4.4 2.1e+02 2.3 0.0 6.9 7 0 0 7 7 7 0 ACT domain Plexin_cytopl PF08337.7 EDO16125.1 - 0.00019 19.8 29.2 5 5.3 0.1 8.8 8 6 0 8 8 8 6 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.6 EDO16125.1 - 0.042 13.7 56.9 6.5 6.8 1.2 7.3 7 0 0 7 7 7 0 Tash protein PEST motif GABP-alpha PF11620.3 EDO16125.1 - 0.074 13.0 18.1 1e+02 2.9 0.1 6.8 7 0 0 7 7 7 0 GA-binding protein alpha chain DUF3781 PF12636.2 EDO16125.1 - 3.8 7.5 18.5 2e+02 2.0 0.1 6.8 7 0 0 7 7 7 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 EDO16125.1 - 6.9 6.7 29.3 94 3.1 0.1 9.1 7 7 0 7 7 7 0 FERM N-terminal domain DUF3722 PF12519.3 EDO16127.1 - 8.4e-75 251.3 10.6 1.4e-74 250.6 7.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Spo7 PF03907.8 EDO16128.1 - 5.5e-91 303.8 8.7 6.5e-91 303.5 6.1 1.0 1 0 0 1 1 1 1 Spo7-like protein DUF4234 PF14018.1 EDO16128.1 - 0.14 11.9 1.8 0.46 10.2 1.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) WD40 PF00400.27 EDO16129.1 - 2.3e-49 163.5 20.4 2.1e-09 36.8 1.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EDO16129.1 - 7.6e-15 54.3 2.5 1.6e-14 53.3 1.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO16129.1 - 2.4e-11 42.9 1.7 5e-11 41.9 1.2 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EDO16129.1 - 7e-11 40.9 11.0 0.011 13.9 0.1 6.0 1 1 5 6 6 6 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EDO16129.1 - 0.0041 16.6 0.1 0.26 10.7 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain PRANC PF09372.5 EDO16129.1 - 0.0069 16.3 0.9 0.0069 16.3 0.6 2.7 2 1 0 2 2 2 1 PRANC domain CBM_21 PF03370.8 EDO16130.1 - 1.2e-31 108.9 3.3 1.2e-31 108.9 2.3 1.7 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit Mito_carr PF00153.22 EDO16131.1 - 1.9e-48 162.1 4.0 3.4e-19 68.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ArfGap PF01412.13 EDO16132.1 - 9.9e-38 128.5 0.3 9.9e-38 128.5 0.2 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf DUF4521 PF15021.1 EDO16132.1 - 2 7.9 10.9 0.1 12.1 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4521) AA_kinase PF00696.23 EDO16133.1 - 1.5e-40 139.2 0.0 2.2e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EDO16133.1 - 2.8e-14 52.2 0.2 4.6e-08 32.3 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EDO16133.1 - 1e-09 37.7 1.3 3.3e-07 29.7 0.2 2.5 2 0 0 2 2 2 2 ACT domain FAD_binding_6 PF00970.19 EDO16134.1 - 2.1e-29 101.5 0.0 3.5e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EDO16134.1 - 7.3e-27 94.1 0.0 1.1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EDO16134.1 - 3.6e-06 26.9 0.0 6.6e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EDO16134.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Cupin_8 PF13621.1 EDO16135.1 - 9.1e-08 31.9 1.5 4.8e-07 29.5 1.1 2.2 1 1 0 1 1 1 1 Cupin-like domain PHD PF00628.24 EDO16135.1 - 2e-05 24.1 6.2 4.8e-05 22.9 4.3 1.7 1 1 0 1 1 1 1 PHD-finger JmjC PF02373.17 EDO16135.1 - 0.0068 16.6 1.0 0.66 10.2 0.0 3.0 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EDO16135.1 - 0.023 13.9 0.0 0.064 12.4 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein Pox_A31 PF05771.6 EDO16135.1 - 0.06 13.1 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A31 protein BRX_N PF13713.1 EDO16135.1 - 0.066 12.6 0.6 0.14 11.6 0.4 1.4 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain BAR_2 PF10455.4 EDO16136.1 - 1.8e-86 289.6 20.1 2.9e-86 288.9 10.1 2.2 2 1 0 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EDO16136.1 - 3.9e-12 46.1 12.8 2.9e-11 43.3 8.2 2.3 1 1 0 1 1 1 1 BAR domain Sec20 PF03908.8 EDO16136.1 - 3.9 7.2 6.6 15 5.4 0.5 2.8 2 0 0 2 2 2 0 Sec20 DUF1993 PF09351.5 EDO16136.1 - 4.1 7.3 7.5 1.4 8.8 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Ofd1_CTDD PF10637.4 EDO16137.1 - 3.5e-95 318.1 3.3 7.3e-89 297.4 2.2 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EDO16137.1 - 1.8e-14 54.0 0.1 4e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EDO16137.1 - 2.2e-07 31.1 0.1 4e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Complex1_LYR_1 PF13232.1 EDO16138.1 - 3.7e-17 62.2 1.1 4.5e-17 62.0 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EDO16138.1 - 6.7e-16 57.8 1.0 8.4e-16 57.5 0.7 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MIF4G PF02854.14 EDO16138.1 - 0.058 12.8 0.2 0.062 12.7 0.2 1.2 1 0 0 1 1 1 0 MIF4G domain Complex1_LYR_2 PF13233.1 EDO16138.1 - 0.062 13.7 1.7 0.076 13.4 1.2 1.1 1 0 0 1 1 1 0 Complex1_LYR-like DnaJ-X PF14308.1 EDO16139.1 - 1.2e-60 204.2 9.1 2.1e-60 203.5 6.3 1.3 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.26 EDO16139.1 - 3.4e-26 90.7 0.7 2.4e-25 88.0 0.2 2.6 2 0 0 2 2 2 1 DnaJ domain Fzo_mitofusin PF04799.8 EDO16139.1 - 0.15 11.4 2.3 0.35 10.2 1.6 1.6 1 0 0 1 1 1 0 fzo-like conserved region Metallophos PF00149.23 EDO16140.1 - 3.1e-29 101.7 5.4 3.1e-29 101.7 3.8 1.4 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase AAA PF00004.24 EDO16141.1 - 2.6e-39 134.4 0.0 7.7e-39 132.9 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EDO16141.1 - 1.8e-09 37.3 0.8 2.4e-05 24.1 0.0 4.7 4 0 0 4 4 4 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EDO16141.1 - 8.5e-06 25.9 1.7 0.00033 20.8 0.1 3.7 4 1 0 4 4 3 1 AAA domain AAA_2 PF07724.9 EDO16141.1 - 1.9e-05 24.6 0.1 6.7e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EDO16141.1 - 6.3e-05 22.1 0.0 0.00014 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDO16141.1 - 0.0012 18.5 0.0 0.0047 16.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EDO16141.1 - 0.0016 17.2 0.0 0.0028 16.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EDO16141.1 - 0.0024 17.8 0.1 0.042 13.8 0.0 2.8 1 1 2 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 EDO16141.1 - 0.0034 16.8 1.1 0.28 10.5 0.1 3.1 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EDO16141.1 - 0.0035 16.7 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EDO16141.1 - 0.0037 16.4 0.1 0.009 15.1 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EDO16141.1 - 0.0042 16.9 1.9 0.044 13.6 0.0 3.0 4 0 0 4 4 3 1 AAA domain AAA_19 PF13245.1 EDO16141.1 - 0.0076 15.9 0.1 0.035 13.8 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EDO16141.1 - 0.0078 16.0 0.0 0.028 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO16141.1 - 0.01 16.6 2.5 0.081 13.7 0.0 3.0 3 1 0 3 3 2 0 AAA domain DUF815 PF05673.8 EDO16141.1 - 0.01 14.7 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EDO16141.1 - 0.03 14.6 0.2 0.22 11.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EDO16141.1 - 0.053 13.4 0.4 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Chromo PF00385.19 EDO16141.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PhoH PF02562.11 EDO16141.1 - 0.1 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NOT2_3_5 PF04153.13 EDO16142.1 - 4.8e-25 87.9 0.1 1e-24 86.9 0.1 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Not3 PF04065.10 EDO16143.1 - 6.6e-92 307.0 29.5 8.6e-92 306.6 20.4 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Syntaxin_2 PF14523.1 EDO16143.1 - 0.0094 15.9 2.0 0.0094 15.9 1.4 2.8 2 0 0 2 2 2 1 Syntaxin-like protein DUF3348 PF11828.3 EDO16143.1 - 0.026 13.9 4.0 0.04 13.3 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3348) DUF1192 PF06698.6 EDO16143.1 - 2 8.3 10.9 0.19 11.5 1.4 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Syntaxin PF00804.20 EDO16143.1 - 3.5 7.8 17.9 2.8 8.1 2.6 3.0 2 1 1 3 3 3 0 Syntaxin DUF1399 PF07173.7 EDO16143.1 - 6.2 7.1 12.1 3 8.1 0.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1399) DUF2370 PF10176.4 EDO16144.1 - 0.042 13.1 1.8 1.1 8.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) BAF1_ABF1 PF04684.8 EDO16144.1 - 0.57 8.9 6.3 0.91 8.3 4.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor bZIP_1 PF00170.16 EDO16146.1 - 7.3e-15 54.6 3.4 1.9e-14 53.3 2.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDO16146.1 - 5.8e-06 26.0 4.8 5.8e-06 26.0 3.3 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EDO16146.1 - 0.028 14.7 1.2 0.028 14.7 0.8 3.9 4 0 0 4 4 4 0 bZIP Maf transcription factor Erg28 PF03694.8 EDO16148.1 - 1e-44 151.0 0.7 1.3e-44 150.6 0.5 1.1 1 0 0 1 1 1 1 Erg28 like protein MtN3_slv PF03083.11 EDO16148.1 - 0.0018 18.1 0.9 0.0049 16.7 0.2 1.9 1 1 1 2 2 2 1 Sugar efflux transporter for intercellular exchange DUF308 PF03729.8 EDO16148.1 - 0.045 13.7 0.5 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) Oxidored_q1_N PF00662.15 EDO16148.1 - 0.96 9.0 3.9 0.26 10.8 0.2 2.0 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus cNMP_binding PF00027.24 EDO16149.1 - 2.2e-42 142.7 0.2 1.8e-22 78.9 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EDO16149.1 - 1e-06 28.0 0.2 2.9e-06 26.6 0.1 1.8 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit SWIRM PF04433.12 EDO16150.1 - 9.3e-33 112.2 0.3 3.5e-32 110.3 0.2 2.1 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EDO16150.1 - 6.7e-09 35.1 2.7 1.1e-08 34.4 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 EDO16150.1 - 8.5e-08 32.1 0.2 6.2e-07 29.4 0.2 2.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EDO16150.1 - 2.4e-06 27.4 0.0 5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Elf1 PF05129.8 EDO16150.1 - 0.0015 18.1 0.8 0.004 16.8 0.6 1.6 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-UBR PF02207.15 EDO16150.1 - 0.089 12.5 0.7 0.17 11.5 0.5 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Zn_ribbon_2 PF12674.2 EDO16150.1 - 0.15 12.4 1.8 0.75 10.1 0.1 2.9 2 1 0 2 2 2 0 Putative zinc ribbon domain Zip PF02535.17 EDO16151.1 - 2.9e-59 200.6 7.6 2.9e-59 200.6 5.2 1.5 2 0 0 2 2 2 1 ZIP Zinc transporter Gly-zipper_YMGG PF13441.1 EDO16151.1 - 0.043 13.3 0.1 0.17 11.3 0.0 2.0 2 1 0 2 2 2 0 YMGG-like Gly-zipper YedD PF13987.1 EDO16152.1 - 0.022 14.3 0.1 0.13 11.8 0.0 1.9 1 1 1 2 2 2 0 YedD-like protein STAG PF08514.6 EDO16153.1 - 5e-09 35.8 2.5 5e-09 35.8 1.8 2.8 2 0 0 2 2 2 1 STAG domain HEAT PF02985.17 EDO16153.1 - 0.004 17.1 0.1 0.55 10.4 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat MecA_N PF05223.6 EDO16153.1 - 2.1 8.4 10.1 12 5.9 0.8 3.9 4 0 0 4 4 4 0 NTF2-like N-terminal transpeptidase domain MMgT PF10270.4 EDO16154.1 - 1.8e-14 54.0 0.5 2e-14 53.9 0.4 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter Glyco_hydro_63 PF03200.11 EDO16155.1 - 9e-218 724.9 9.3 6.9e-217 722.0 6.4 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 EDO16155.1 - 8e-07 28.1 0.1 2.4e-06 26.5 0.1 1.8 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase FlaE PF07559.9 EDO16155.1 - 0.036 14.7 0.2 0.085 13.5 0.2 1.6 1 0 0 1 1 1 0 Flagellar basal body protein FlaE MHC_I_C PF06623.6 EDO16155.1 - 0.26 10.7 3.0 0.12 11.8 0.2 1.8 2 0 0 2 2 2 0 MHC_I C-terminus Macoilin PF09726.4 EDO16156.1 - 1.3 7.2 23.1 1.8 6.7 16.0 1.1 1 0 0 1 1 1 0 Transmembrane protein rve PF00665.21 EDO16157.1 - 5.4e-17 62.0 0.0 6.6e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain Ribosomal_L7Ae PF01248.21 EDO16159.1 - 1.1e-24 85.7 0.0 1.3e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Mito_fiss_Elm1 PF06258.6 EDO16159.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Ribosomal_L24e PF01246.15 EDO16160.1 - 2.5e-34 116.9 0.3 2.5e-34 116.9 0.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L24e DUF964 PF06133.6 EDO16160.1 - 0.088 12.8 4.2 0.13 12.2 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF964) RR_TM4-6 PF06459.7 EDO16160.1 - 4.8 7.0 8.5 5.6 6.7 5.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1279 PF06916.8 EDO16161.1 - 7.3e-24 83.8 0.0 1.5e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Spore_coat_CotO PF14153.1 EDO16161.1 - 0.025 14.0 0.3 0.032 13.6 0.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Gly_transf_sug PF04488.10 EDO16164.1 - 2e-13 50.6 0.1 5.7e-13 49.1 0.1 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EDO16164.1 - 0.0015 17.1 0.7 0.028 12.8 0.0 2.5 3 0 0 3 3 3 2 TcdA/TcdB catalytic glycosyltransferase domain Ras PF00071.17 EDO16165.1 - 3.1e-49 166.4 0.1 4.5e-49 165.9 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO16165.1 - 5.2e-18 65.6 0.9 9e-18 64.8 0.1 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDO16165.1 - 5.1e-08 32.3 0.1 7.4e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO16165.1 - 3.3e-06 26.6 0.9 6.1e-06 25.8 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO16165.1 - 0.0036 17.2 0.1 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Bac_chlorC PF02043.12 EDO16165.1 - 0.01 15.6 1.8 0.44 10.3 0.0 2.5 2 1 0 2 2 2 0 Bacteriochlorophyll C binding protein AAA_24 PF13479.1 EDO16165.1 - 0.017 14.7 0.1 0.07 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain D5_N PF08706.6 EDO16165.1 - 0.033 14.2 0.0 0.057 13.5 0.0 1.4 1 0 0 1 1 1 0 D5 N terminal like PALP PF00291.20 EDO16166.1 - 4.5e-56 190.3 0.0 5.6e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EDO16166.1 - 6.6e-15 54.6 0.1 5.7e-11 42.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain ComZ PF10815.3 EDO16167.1 - 0.0048 16.6 0.3 0.0086 15.8 0.2 1.5 1 0 0 1 1 1 1 ComZ Flg_hook PF02120.11 EDO16167.1 - 0.067 12.8 0.2 0.19 11.3 0.1 1.8 1 1 0 1 1 1 0 Flagellar hook-length control protein FliK CLTH PF10607.4 EDO16167.1 - 0.23 11.1 1.2 0.27 10.9 0.9 1.3 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain TFIIS_M PF07500.9 EDO16168.1 - 1.1e-26 93.1 2.2 1.1e-26 93.1 1.5 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EDO16168.1 - 3.4e-17 61.7 6.3 3.4e-17 61.7 4.4 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EDO16168.1 - 2.2e-13 49.4 2.7 4.6e-13 48.4 1.9 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Ribosomal_S27 PF01599.14 EDO16168.1 - 0.45 10.3 3.8 2.2 8.1 0.1 2.8 3 0 0 3 3 3 0 Ribosomal protein S27a Zn_Tnp_IS1595 PF12760.2 EDO16168.1 - 1.7 8.5 5.6 6.9 6.5 4.0 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain DUF445 PF04286.7 EDO16168.1 - 2.2 7.7 6.9 1.4 8.4 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) RRM_1 PF00076.17 EDO16169.1 - 3.8e-20 71.3 0.0 7e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO16169.1 - 1.9e-12 46.9 0.0 3.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO16169.1 - 2.8e-09 36.6 0.0 4.8e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EDO16169.1 - 6.6e-07 28.5 0.7 1.2e-06 27.6 0.5 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.1 EDO16169.1 - 4.9e-06 26.5 0.2 4.9e-06 26.5 0.1 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Med30 PF11315.3 EDO16169.1 - 0.067 13.3 1.1 0.11 12.6 0.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 30 PEMT PF04191.8 EDO16170.1 - 7.7e-55 183.5 16.0 2.7e-33 114.2 1.0 3.2 4 0 0 4 4 4 2 Phospholipid methyltransferase RNase_PH PF01138.16 EDO16171.1 - 1.7e-08 34.8 0.1 2.4e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Arrestin_N PF00339.24 EDO16172.1 - 6.7e-19 68.1 0.1 2e-17 63.3 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EDO16172.1 - 5.5e-08 33.0 0.6 5.5e-08 33.0 0.4 3.7 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain RRM_1 PF00076.17 EDO16173.1 - 2.9e-42 142.1 0.0 7.5e-20 70.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO16173.1 - 5.4e-31 106.3 0.0 1.1e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO16173.1 - 1.6e-20 72.7 0.0 2.8e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDO16173.1 - 0.00043 19.9 0.0 0.0022 17.6 0.0 2.2 1 0 0 1 1 1 1 Limkain b1 Nup35_RRM_2 PF14605.1 EDO16173.1 - 0.1 12.3 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Microtub_assoc PF07989.6 EDO16175.1 - 0.022 14.5 1.1 0.074 12.8 0.7 1.9 1 0 0 1 1 1 0 Microtubule associated XH PF03469.9 EDO16175.1 - 0.029 14.0 0.4 0.047 13.3 0.3 1.3 1 0 0 1 1 1 0 XH domain Herpes_BLRF2 PF05812.7 EDO16175.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Cep57_CLD_2 PF14197.1 EDO16175.1 - 1.9 8.4 11.4 0.05 13.5 3.3 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Glyco_tran_28_C PF04101.11 EDO16176.1 - 2.5e-26 92.3 0.2 8e-25 87.4 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EDO16176.1 - 0.0021 17.3 0.0 0.0035 16.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 1 MIF4G PF02854.14 EDO16177.1 - 1.5e-42 145.4 0.4 2.9e-42 144.4 0.3 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EDO16177.1 - 1.5e-27 95.2 2.0 1.5e-27 95.2 1.4 2.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 TYW3 PF02676.9 EDO16178.1 - 2.7e-67 225.8 0.0 3.5e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Gtr1_RagA PF04670.7 EDO16179.1 - 3.5e-68 229.2 0.8 5.3e-68 228.6 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EDO16179.1 - 0.0012 18.0 0.0 0.003 16.8 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family AsnC_trans_reg PF01037.16 EDO16179.1 - 0.1 12.3 0.0 0.31 10.7 0.0 1.8 1 0 0 1 1 1 0 AsnC family Aconitase PF00330.15 EDO16181.1 - 4.2e-180 599.2 0.0 7.6e-180 598.3 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDO16181.1 - 1.9e-45 154.1 0.0 3.8e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Polysacc_deac_1 PF01522.16 EDO16182.1 - 6.1e-25 87.2 0.0 1e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase GRIP PF01465.15 EDO16183.1 - 2.1e-15 55.9 0.2 6.5e-15 54.3 0.2 1.9 1 0 0 1 1 1 1 GRIP domain CENP-F_leu_zip PF10473.4 EDO16183.1 - 1.1 9.1 173.8 0.017 14.9 14.0 9.3 2 2 7 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EDO16183.1 - 1.5 7.9 87.4 0.048 12.8 7.4 7.3 2 2 6 8 8 8 0 Reovirus sigma C capsid protein BicD PF09730.4 EDO16183.1 - 1.9 6.7 148.1 0.5 8.6 19.8 4.5 1 1 3 4 4 4 0 Microtubule-associated protein Bicaudal-D RasGEF PF00617.14 EDO16184.1 - 7e-58 195.4 2.7 1.2e-57 194.7 0.5 2.5 2 0 0 2 2 2 1 RasGEF domain SH3_9 PF14604.1 EDO16184.1 - 8.8e-07 28.4 0.1 1.9e-06 27.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDO16184.1 - 4.8e-06 25.8 0.6 1.4e-05 24.4 0.2 2.0 2 0 0 2 2 2 1 SH3 domain RasGEF_N PF00618.15 EDO16184.1 - 3.5e-05 23.8 0.5 3.5e-05 23.8 0.4 4.2 3 1 0 3 3 3 1 RasGEF N-terminal motif SH3_2 PF07653.12 EDO16184.1 - 0.0035 16.7 0.2 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain tRNA-synt_2 PF00152.15 EDO16185.1 - 4.6e-47 160.4 2.6 4.6e-47 160.4 1.8 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDO16185.1 - 2e-08 33.9 0.1 5.4e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain SR-25 PF10500.4 EDO16185.1 - 0.33 10.3 9.5 0.63 9.4 6.5 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SPC25 PF06703.6 EDO16186.1 - 3.5e-47 159.9 2.4 4e-47 159.8 1.7 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) adh_short PF00106.20 EDO16187.1 - 2e-17 63.6 0.0 4.8e-17 62.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO16187.1 - 2.7e-05 23.9 0.0 0.00031 20.4 0.0 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDO16187.1 - 4.3e-05 23.4 0.0 5.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDO16187.1 - 0.0034 16.8 0.2 0.087 12.2 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EDO16187.1 - 0.041 13.8 0.0 0.069 13.1 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EDO16187.1 - 0.051 12.2 0.1 0.075 11.7 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FMN_dh PF01070.13 EDO16188.1 - 3.1e-117 391.3 0.0 3.9e-117 391.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EDO16188.1 - 2e-20 72.3 0.0 4.3e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EDO16188.1 - 1.6e-07 30.5 0.0 3.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EDO16188.1 - 0.0021 17.0 0.4 0.0097 14.8 0.1 2.2 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EDO16188.1 - 0.016 14.3 0.1 0.035 13.2 0.0 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase ThiG PF05690.9 EDO16188.1 - 0.078 12.0 0.0 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Citrate_synt PF00285.16 EDO16189.1 - 2.5e-101 338.9 0.0 3e-101 338.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Pkinase PF00069.20 EDO16190.1 - 1.8e-64 217.3 0.0 4.4e-64 216.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16190.1 - 2.1e-26 92.5 0.0 3.1e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO16190.1 - 0.011 15.4 0.0 0.029 14.0 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EDO16190.1 - 0.029 13.3 0.0 0.31 9.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like RIO1 PF01163.17 EDO16190.1 - 0.03 13.6 0.2 0.076 12.3 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 EDO16190.1 - 0.032 13.7 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EDO16190.1 - 0.09 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BAR PF03114.13 EDO16191.1 - 1.5e-53 181.6 2.4 1.8e-53 181.4 1.6 1.0 1 0 0 1 1 1 1 BAR domain DUF1496 PF07383.7 EDO16191.1 - 0.0019 17.4 0.5 0.0038 16.4 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1496) Seryl_tRNA_N PF02403.17 EDO16191.1 - 0.14 12.1 3.4 1.3 9.0 0.5 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FIVAR PF07554.8 EDO16191.1 - 0.26 11.5 1.7 9.2 6.6 0.1 3.5 3 0 0 3 3 3 0 Uncharacterised Sugar-binding Domain Grp1_Fun34_YaaH PF01184.14 EDO16192.1 - 1.3e-90 302.3 19.9 1.5e-90 302.1 13.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 EDO16192.1 - 1.6 7.6 6.9 0.99 8.3 3.5 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) RNA_pol_Rpc34 PF05158.7 EDO16193.1 - 8.5e-106 353.8 4.3 1e-105 353.5 3.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.15 EDO16193.1 - 0.03 14.4 1.2 0.051 13.7 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulator HTH_3 PF01381.17 EDO16193.1 - 0.043 13.6 0.4 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix B-block_TFIIIC PF04182.7 EDO16193.1 - 0.06 13.2 2.1 0.22 11.3 0.1 2.3 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC HAD PF12710.2 EDO16194.1 - 7.4e-09 36.0 0.0 9.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TPR_11 PF13414.1 EDO16195.1 - 9.5e-15 54.0 5.3 8.2e-10 38.2 0.1 4.7 3 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.1 EDO16195.1 - 3.2e-08 33.4 0.0 0.057 14.0 0.0 5.3 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO16195.1 - 1.3e-07 31.4 1.7 0.0087 15.9 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDO16195.1 - 3.7e-06 27.1 0.1 0.14 12.5 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO16195.1 - 5e-05 22.7 1.5 0.42 10.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDO16195.1 - 0.00011 22.0 2.1 0.25 11.6 0.0 4.2 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO16195.1 - 0.00058 19.5 12.1 0.0068 16.2 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO16195.1 - 0.00074 19.1 5.0 0.64 9.9 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO16195.1 - 0.0015 19.1 7.8 0.79 10.4 0.1 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat RPN7 PF10602.4 EDO16195.1 - 0.024 14.0 0.9 0.67 9.3 0.0 3.1 3 1 0 3 3 3 0 26S proteasome subunit RPN7 Apc3 PF12895.2 EDO16195.1 - 0.1 12.7 6.0 1 9.5 1.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 CagX PF03524.10 EDO16196.1 - 0.049 12.8 3.6 0.087 12.0 2.5 1.3 1 0 0 1 1 1 0 Conjugal transfer protein BAF1_ABF1 PF04684.8 EDO16196.1 - 0.13 11.1 29.6 0.26 10.0 20.5 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Dpoe2NT PF12213.3 EDO16196.1 - 0.18 11.7 1.5 2.1 8.2 0.1 2.4 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal Zip PF02535.17 EDO16196.1 - 0.22 10.5 4.2 0.28 10.1 2.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Myb_DNA-bind_4 PF13837.1 EDO16196.1 - 1.7 8.8 5.9 0.26 11.4 0.3 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain ATP11 PF06644.6 EDO16197.1 - 9.6e-100 333.4 0.4 1.1e-99 333.2 0.3 1.0 1 0 0 1 1 1 1 ATP11 protein Capsule_synth PF05159.9 EDO16197.1 - 0.03 13.7 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein zf-rbx1 PF12678.2 EDO16198.1 - 1.1e-32 111.9 13.9 1.3e-32 111.6 9.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDO16198.1 - 2.5e-17 62.4 9.8 3.2e-17 62.1 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EDO16198.1 - 2.6e-07 30.3 12.1 2e-06 27.5 8.4 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDO16198.1 - 0.0005 19.6 12.7 0.0032 17.0 8.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO16198.1 - 0.019 14.6 10.3 0.86 9.3 7.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EDO16198.1 - 0.028 13.9 3.1 0.049 13.1 2.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 EDO16198.1 - 0.063 13.3 11.5 4.4 7.4 8.0 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO16198.1 - 0.12 12.2 7.6 0.12 12.2 0.3 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EDO16198.1 - 0.19 11.4 7.3 1.5 8.5 5.1 2.4 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EDO16198.1 - 0.21 11.3 11.9 1.6 8.4 8.3 2.4 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 EDO16198.1 - 0.54 10.4 9.4 40 4.4 6.5 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.3 EDO16198.1 - 0.59 10.1 9.8 2.7 8.0 6.9 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Med7 PF05983.6 EDO16199.1 - 1.6e-31 109.3 3.2 1.7e-31 109.1 2.2 1.0 1 0 0 1 1 1 1 MED7 protein DASH_Spc34 PF08657.5 EDO16199.1 - 0.017 14.7 1.0 0.018 14.7 0.7 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 Snapin_Pallidin PF14712.1 EDO16199.1 - 0.083 13.2 1.4 5.8 7.2 0.1 2.1 1 1 1 2 2 2 0 Snapin/Pallidin DUF607 PF04678.8 EDO16199.1 - 0.1 12.4 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF607 CENP-F_N PF10481.4 EDO16199.1 - 0.12 11.7 1.1 0.11 11.7 0.8 1.1 1 0 0 1 1 1 0 Cenp-F N-terminal domain WD40 PF00400.27 EDO16200.1 - 1.6e-42 141.9 9.7 3.5e-10 39.3 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EDO16200.1 - 5.5e-05 22.9 2.6 0.12 12.0 0.1 3.2 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EDO16200.1 - 9.3e-05 21.3 0.9 1.5 7.4 0.0 3.8 1 1 1 4 4 4 2 Nup133 N terminal like DUF3312 PF11768.3 EDO16200.1 - 0.1 10.8 0.0 0.37 8.9 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) MFS_1 PF07690.11 EDO16201.1 - 4.3e-18 65.1 34.1 4.1e-16 58.6 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO16202.1 - 2e-119 399.1 36.6 6.5e-119 397.4 25.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO16202.1 - 1.2e-23 83.3 35.2 2.2e-19 69.3 17.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1213 PF06740.7 EDO16202.1 - 0.9 9.6 3.4 1.3 9.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) IF4E PF01652.13 EDO16203.1 - 2e-55 186.8 0.2 2.4e-55 186.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Na_Ca_ex PF01699.19 EDO16204.1 - 3e-22 78.7 42.5 6.5e-16 58.2 8.3 3.4 4 1 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EDO16204.1 - 2.4e-10 40.6 7.0 2.4e-10 40.6 4.9 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF307) Aminotran_3 PF00202.16 EDO16205.1 - 7e-109 363.7 0.0 8.2e-109 363.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PucR PF07905.6 EDO16205.1 - 0.084 12.4 0.0 0.56 9.7 0.0 2.3 3 0 0 3 3 3 0 Purine catabolism regulatory protein-like family Aminotran_5 PF00266.14 EDO16205.1 - 0.085 11.5 0.0 0.14 10.8 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class-V LCM PF04072.9 EDO16206.1 - 1.2e-23 83.6 0.0 2.1e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EDO16206.1 - 1e-17 63.6 4.0 2.7e-07 30.2 0.0 5.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EDO16206.1 - 2e-10 40.5 0.9 0.0029 17.7 0.0 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 EDO16206.1 - 1.5e-08 34.4 6.3 0.006 16.7 0.0 6.1 4 1 2 6 6 6 2 Kelch motif Kelch_5 PF13854.1 EDO16206.1 - 5.4e-08 32.6 0.0 0.11 12.4 0.0 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 EDO16206.1 - 0.00014 21.3 5.5 0.029 13.9 0.0 4.7 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 EDO16206.1 - 0.00055 19.5 1.8 0.034 13.9 0.0 4.3 5 0 0 5 5 5 1 Kelch motif Syja_N PF02383.13 EDO16207.1 - 2.5e-91 305.8 0.2 4.9e-91 304.8 0.1 1.5 1 0 0 1 1 1 1 SacI homology domain UBA_e1_C PF09358.5 EDO16208.1 - 0.0085 16.2 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain zf-DHHC PF01529.15 EDO16209.1 - 3.1e-35 121.1 18.0 3.1e-35 121.1 12.5 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase TMEMspv1-c74-12 PF11044.3 EDO16209.1 - 0.006 16.0 0.5 0.006 16.0 0.3 3.5 3 1 1 4 4 4 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Phage_holin PF04688.8 EDO16209.1 - 3.2 7.3 10.7 0.31 10.6 1.4 3.0 2 1 0 2 2 2 0 Phage lysis protein, holin Flocculin_t3 PF13928.1 EDO16210.1 - 0.00073 19.6 7.2 0.00073 19.6 5.0 13.3 6 4 2 8 8 8 3 Flocculin type 3 repeat AAA PF00004.24 EDO16211.1 - 4e-56 188.8 0.0 2e-44 150.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDO16211.1 - 9.1e-07 29.7 0.1 0.0057 17.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EDO16211.1 - 5.9e-05 23.2 0.1 0.017 15.2 0.0 3.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDO16211.1 - 6.7e-05 22.3 1.5 0.039 13.3 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EDO16211.1 - 0.0001 22.3 0.2 0.092 12.7 0.0 3.3 2 1 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 EDO16211.1 - 0.00022 21.3 0.0 0.015 15.4 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Parvo_NS1 PF01057.12 EDO16211.1 - 0.00023 20.1 0.0 0.00087 18.2 0.0 1.9 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.9 EDO16211.1 - 0.00029 20.8 0.0 0.0071 16.2 0.0 2.8 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EDO16211.1 - 0.00042 19.4 0.0 0.00097 18.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 EDO16211.1 - 0.00097 18.3 0.2 0.029 13.4 0.0 2.6 3 0 0 3 3 3 1 KaiC AAA_18 PF13238.1 EDO16211.1 - 0.0015 18.8 2.1 0.51 10.6 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_5 PF07728.9 EDO16211.1 - 0.0029 17.3 0.0 0.024 14.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EDO16211.1 - 0.0032 16.8 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EDO16211.1 - 0.0045 16.8 0.0 0.11 12.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO16211.1 - 0.007 16.1 0.1 0.049 13.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 EDO16211.1 - 0.0073 15.0 0.2 0.031 12.9 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_28 PF13521.1 EDO16211.1 - 0.0078 16.1 0.1 0.56 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EDO16211.1 - 0.015 14.4 0.3 0.04 13.0 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EDO16211.1 - 0.034 14.0 0.0 0.6 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EDO16211.1 - 0.044 13.0 0.0 0.088 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 EDO16211.1 - 0.048 13.2 0.1 0.17 11.4 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EDO16211.1 - 0.098 12.2 0.1 1.4 8.3 0.0 2.7 3 1 0 3 3 3 0 AAA domain AAA_30 PF13604.1 EDO16211.1 - 0.71 9.4 0.6 1.8 8.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.1 EDO16212.1 - 6.1e-30 102.9 29.5 2.3e-10 40.2 0.8 10.5 9 2 2 12 12 12 6 Tetratricopeptide repeat TPR_11 PF13414.1 EDO16212.1 - 7.8e-30 102.3 35.9 7.3e-09 35.1 1.5 10.9 7 2 5 12 12 12 8 TPR repeat TPR_2 PF07719.12 EDO16212.1 - 1.3e-29 99.6 39.8 4.6e-05 23.0 0.0 13.2 14 1 1 15 15 14 9 Tetratricopeptide repeat TPR_1 PF00515.23 EDO16212.1 - 2e-27 93.6 43.4 4.2e-07 29.3 0.0 13.4 13 1 1 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.1 EDO16212.1 - 9.9e-21 73.8 15.3 0.0077 16.5 0.0 10.7 9 2 3 12 12 12 6 Tetratricopeptide repeat TPR_14 PF13428.1 EDO16212.1 - 8.9e-19 66.2 4.9 0.088 13.4 0.0 10.9 9 4 3 12 12 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EDO16212.1 - 1.6e-18 66.8 3.0 0.017 15.8 0.0 9.1 8 2 1 10 10 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDO16212.1 - 3.1e-15 54.7 41.8 0.00019 20.9 0.0 12.6 13 1 1 14 14 13 5 Tetratricopeptide repeat TPR_17 PF13431.1 EDO16212.1 - 8.3e-15 53.6 11.6 1.2 9.4 0.0 11.8 11 1 0 11 11 11 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO16212.1 - 3.9e-12 46.1 28.3 0.001 19.1 0.1 8.8 5 3 4 9 9 9 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EDO16212.1 - 2.8e-09 36.0 24.9 1.1 9.2 0.2 11.1 12 1 0 12 12 11 4 Tetratricopeptide repeat TPR_6 PF13174.1 EDO16212.1 - 1.1e-06 28.6 26.4 7.3 7.2 0.0 12.8 14 0 0 14 14 14 1 Tetratricopeptide repeat TPR_10 PF13374.1 EDO16212.1 - 0.00019 21.2 14.7 22 5.1 0.0 9.7 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDO16212.1 - 0.003 17.3 0.1 0.22 11.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDO16212.1 - 0.017 15.0 7.8 9.6 6.1 0.0 6.2 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.15 EDO16212.1 - 0.019 14.8 0.5 5.9 7.1 0.0 4.9 5 0 0 5 5 5 0 PPR repeat MIT PF04212.13 EDO16212.1 - 0.038 13.8 0.1 0.038 13.8 0.0 6.8 7 1 0 7 7 6 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 EDO16212.1 - 0.16 12.6 3.0 7.4 7.3 0.1 4.4 4 0 0 4 4 3 0 Sel1 repeat DCP1 PF06058.8 EDO16213.1 - 1.2e-16 60.8 3.1 1.4e-09 38.0 0.0 3.1 2 1 1 3 3 3 3 Dcp1-like decapping family DUF3445 PF11927.3 EDO16213.1 - 0.0069 15.7 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyoxalase PF00903.20 EDO16213.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Kelch_1 PF01344.20 EDO16213.1 - 0.15 11.6 0.4 0.58 9.7 0.1 2.0 2 0 0 2 2 2 0 Kelch motif GFO_IDH_MocA PF01408.17 EDO16214.1 - 1.1e-23 83.9 0.0 2.6e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EDO16214.1 - 1.8e-08 34.1 0.0 4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EDO16214.1 - 0.00039 20.8 0.0 0.00094 19.5 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain HSP70 PF00012.15 EDO16215.1 - 7.8e-236 783.6 9.8 8.7e-236 783.5 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO16215.1 - 9.5e-17 60.5 1.2 2.5e-15 55.9 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EDO16215.1 - 0.0005 19.7 0.0 0.00094 18.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2603 PF10788.4 EDO16215.1 - 0.065 12.9 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) FtsA PF14450.1 EDO16215.1 - 5 6.9 11.9 12 5.7 0.2 4.4 2 2 1 3 3 3 0 Cell division protein FtsA KH_1 PF00013.24 EDO16216.1 - 6.6e-11 41.6 1.1 1.6e-10 40.4 0.3 1.9 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 EDO16216.1 - 3.3e-07 29.8 1.0 7.3e-07 28.7 0.5 1.8 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 EDO16216.1 - 7.3e-05 22.2 0.1 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 KH domain FUSC_2 PF13515.1 EDO16217.1 - 7.9e-07 29.0 26.7 8.7e-07 28.9 5.3 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF2422 PF10337.4 EDO16217.1 - 7.3e-06 25.0 14.1 0.0002 20.3 3.7 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EDO16217.1 - 7.7e-06 25.6 0.5 0.0009 18.9 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2421) DUF1664 PF07889.7 EDO16217.1 - 0.071 12.9 0.3 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2697 PF10906.3 EDO16218.1 - 2.8e-34 116.9 1.6 3.3e-34 116.7 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) VID27 PF08553.5 EDO16219.1 - 1.2e-45 156.0 3.8 1.3e-45 155.9 2.6 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein CLU_N PF15044.1 EDO16219.1 - 0.034 14.3 0.7 0.071 13.2 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial function, CLU-N-term LIM_bind PF01803.11 EDO16220.1 - 2.6e-58 196.9 0.1 2.6e-58 196.9 0.0 4.9 3 1 3 6 6 6 1 LIM-domain binding protein RabGAP-TBC PF00566.13 EDO16221.1 - 7.6e-31 107.2 24.3 1.4e-29 103.0 14.1 2.9 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EDO16221.1 - 2.4e-06 26.9 0.1 0.0003 20.1 0.1 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3548) YfkD PF14167.1 EDO16221.1 - 0.012 14.6 0.2 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 YfkD-like protein MgsA_C PF12002.3 EDO16222.1 - 5.2e-53 179.1 0.6 1.3e-52 177.9 0.4 1.7 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EDO16222.1 - 3.9e-17 62.6 0.4 2.6e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO16222.1 - 2.3e-15 56.2 0.0 5.2e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDO16222.1 - 3e-09 37.1 0.2 5.4e-06 26.5 0.0 2.6 1 1 1 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 EDO16222.1 - 3.8e-09 36.5 0.0 8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EDO16222.1 - 3.1e-07 30.1 0.0 6.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EDO16222.1 - 4.9e-06 26.1 0.0 5.4e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.8 EDO16222.1 - 5e-06 25.6 0.0 9e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EDO16222.1 - 5.6e-06 26.5 1.0 0.00015 21.9 0.7 2.5 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EDO16222.1 - 1.3e-05 24.6 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EDO16222.1 - 8.8e-05 22.8 0.4 0.0014 18.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.16 EDO16222.1 - 9e-05 21.7 0.2 0.15 11.2 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 EDO16222.1 - 0.00037 20.1 0.0 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 EDO16222.1 - 0.00065 19.7 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 EDO16222.1 - 0.00095 19.9 0.0 0.0028 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.1 EDO16222.1 - 0.0022 17.6 2.7 0.01 15.5 0.1 2.8 2 1 0 2 2 2 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EDO16222.1 - 0.0025 16.5 0.2 0.3 9.7 0.1 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein KTI12 PF08433.5 EDO16222.1 - 0.0025 17.0 1.8 0.012 14.8 0.0 2.7 3 0 0 3 3 3 1 Chromatin associated protein KTI12 AAA_2 PF07724.9 EDO16222.1 - 0.0044 16.9 0.1 0.013 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 EDO16222.1 - 0.0049 17.1 0.1 0.015 15.5 0.0 2.1 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 EDO16222.1 - 0.0064 16.4 0.2 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EDO16222.1 - 0.0072 15.7 0.3 0.4 10.0 0.0 2.4 1 1 0 2 2 2 1 AAA-like domain Arch_ATPase PF01637.13 EDO16222.1 - 0.0073 16.0 0.3 0.035 13.8 0.2 2.1 1 1 0 1 1 1 1 Archaeal ATPase AAA_3 PF07726.6 EDO16222.1 - 0.0074 15.8 0.0 0.044 13.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EDO16222.1 - 0.0077 14.9 0.2 0.032 12.9 0.0 1.9 2 1 1 3 3 3 1 TIP49 C-terminus zf-C2HC_2 PF13913.1 EDO16222.1 - 0.01 15.4 0.2 0.02 14.5 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type PRP21_like_P PF12230.3 EDO16222.1 - 0.01 15.3 0.2 0.023 14.1 0.1 1.6 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein ResIII PF04851.10 EDO16222.1 - 0.016 15.0 1.2 0.34 10.7 0.3 2.6 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EDO16222.1 - 0.016 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EDO16222.1 - 0.018 15.1 0.6 0.059 13.5 0.0 2.2 3 0 0 3 3 1 0 RNA helicase KAP_NTPase PF07693.9 EDO16222.1 - 0.019 13.9 1.1 0.88 8.4 0.3 2.3 1 1 1 2 2 2 0 KAP family P-loop domain AAA_24 PF13479.1 EDO16222.1 - 0.028 14.0 0.1 0.079 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EDO16222.1 - 0.037 13.6 0.0 0.19 11.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDO16222.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sgf11 PF08209.6 EDO16222.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) AAA_28 PF13521.1 EDO16222.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EDO16222.1 - 0.076 12.1 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Glyco_transf_22 PF03901.12 EDO16223.1 - 1.1e-87 294.7 27.2 1.4e-87 294.3 18.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ras PF00071.17 EDO16225.1 - 5e-33 113.7 0.1 7.3e-33 113.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO16225.1 - 3.2e-09 37.3 0.1 7.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein DAD PF02109.11 EDO16226.1 - 6.8e-40 135.6 6.8 8.9e-40 135.2 4.7 1.1 1 0 0 1 1 1 1 DAD family Y_phosphatase2 PF03162.8 EDO16227.1 - 4.6e-56 188.7 0.0 6.6e-56 188.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EDO16227.1 - 1.2e-05 25.6 0.0 9.1e-05 22.7 0.0 2.1 1 1 1 2 2 2 1 Tyrosine phosphatase family Serglycin PF04360.7 EDO16227.1 - 0.016 14.9 1.8 0.027 14.1 1.2 1.3 1 0 0 1 1 1 0 Serglycin DSPc PF00782.15 EDO16227.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF2457 PF10446.4 EDO16227.1 - 3.3 6.3 20.5 4.4 5.9 14.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EDO16227.1 - 3.8 7.0 8.4 5.4 6.5 5.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 EDO16227.1 - 5.3 5.3 12.1 6.6 5.0 8.4 1.1 1 0 0 1 1 1 0 Daxx Family PBP1_TM PF14812.1 EDO16227.1 - 5.7 7.3 14.8 11 6.3 10.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ApoO PF09769.4 EDO16228.1 - 1.6e-07 31.1 0.0 0.012 15.3 0.0 3.2 3 0 0 3 3 3 3 Apolipoprotein O Aa_trans PF01490.13 EDO16229.1 - 2.3e-99 332.6 33.6 2.8e-99 332.3 23.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein bZIP_2 PF07716.10 EDO16230.1 - 0.00012 21.7 3.0 0.00012 21.7 2.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Upf2 PF04050.9 EDO16230.1 - 0.42 10.3 23.6 0.91 9.2 9.5 2.6 2 0 0 2 2 2 0 Up-frameshift suppressor 2 TSC22 PF01166.13 EDO16230.1 - 2.7 8.0 8.6 0.67 9.9 1.1 3.5 4 1 1 5 5 5 0 TSC-22/dip/bun family RGS PF00615.14 EDO16231.1 - 4.1e-07 30.0 2.8 6.6e-07 29.4 1.9 1.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain HMGL-like PF00682.14 EDO16232.1 - 1.8e-76 256.9 0.0 2.5e-76 256.4 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EDO16232.1 - 1.9e-26 92.4 0.2 4.2e-26 91.2 0.1 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Syja_N PF02383.13 EDO16233.1 - 2.9e-89 298.9 0.1 4.7e-89 298.2 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EDO16233.1 - 4e-23 82.6 0.1 7.1e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.11 EDO16234.1 - 4.3e-35 119.2 0.5 6.6e-35 118.7 0.3 1.3 1 0 0 1 1 1 1 YEATS family His_Phos_1 PF00300.17 EDO16235.1 - 7.3e-22 78.1 0.0 3.5e-21 75.9 0.0 2.1 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.4 EDO16235.1 - 6.3e-16 57.5 0.0 1.5e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 TFIIIC subunit TRAP_alpha PF03896.11 EDO16235.1 - 0.57 9.1 10.1 1.1 8.2 7.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit GEMIN8 PF15348.1 EDO16235.1 - 6.3 6.7 14.6 3.1 7.7 7.1 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Maf PF02545.9 EDO16236.1 - 1.2e-51 174.5 0.1 1.5e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein SAD_SRA PF02182.12 EDO16236.1 - 0.041 13.1 0.1 0.06 12.6 0.1 1.2 1 0 0 1 1 1 0 SAD/SRA domain Cyt-b5 PF00173.23 EDO16237.1 - 2.3e-27 94.5 0.1 3e-27 94.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 7kD_coat PF02495.12 EDO16237.1 - 0.2 11.1 1.1 5 6.6 0.0 2.3 2 0 0 2 2 2 0 7kD viral coat protein zf-C2H2 PF00096.21 EDO16238.1 - 2.8e-16 58.7 18.2 3.6e-06 26.9 0.8 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO16238.1 - 6.8e-14 51.3 21.4 1.9e-08 34.1 1.4 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO16238.1 - 3e-10 39.6 14.7 0.00037 20.6 0.7 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO16238.1 - 0.0031 17.6 12.4 0.049 13.7 0.5 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO16238.1 - 0.013 15.6 11.8 0.017 15.3 0.5 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EDO16238.1 - 0.021 14.7 11.8 0.19 11.7 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.10 EDO16238.1 - 0.03 14.0 13.8 0.49 10.1 1.2 3.0 2 1 1 3 3 3 0 BED zinc finger EFG_II PF14492.1 EDO16238.1 - 0.14 11.9 0.6 0.91 9.4 0.0 2.5 3 0 0 3 3 3 0 Elongation Factor G, domain II zf-CHCC PF10276.4 EDO16238.1 - 0.16 11.7 3.2 0.16 11.7 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger domain zf-Di19 PF05605.7 EDO16238.1 - 0.26 11.4 2.6 0.53 10.4 1.8 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Endonuclease_7 PF02945.10 EDO16238.1 - 1.7 8.4 6.9 6.4 6.5 4.8 2.0 1 1 0 1 1 1 0 Recombination endonuclease VII zf-C2H2_2 PF12756.2 EDO16238.1 - 5.1 7.2 12.7 64 3.7 4.2 3.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) KRAB PF01352.22 EDO16239.1 - 0.039 13.3 0.1 0.1 12.0 0.1 1.7 1 1 0 1 1 1 0 KRAB box ATP_bind_3 PF01171.15 EDO16239.1 - 0.77 9.2 4.7 0.27 10.7 0.8 2.1 2 1 1 3 3 3 0 PP-loop family DUF2417 PF10329.4 EDO16240.1 - 1.9e-79 266.3 8.3 2.4e-79 265.9 5.8 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EDO16240.1 - 6.2e-10 39.3 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO16240.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold FHA PF00498.21 EDO16241.1 - 2.7e-15 56.2 0.0 7.6e-15 54.7 0.0 1.9 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EDO16241.1 - 1.4e-06 28.0 10.6 2.3e-06 27.3 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO16241.1 - 3.8e-06 26.8 4.5 8e-06 25.8 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EDO16241.1 - 0.00088 19.0 5.0 0.0017 18.1 3.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EDO16241.1 - 0.0012 18.4 10.7 0.0024 17.4 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO16241.1 - 0.011 15.4 8.4 0.019 14.6 5.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Sec_GG PF07549.9 EDO16241.1 - 0.081 12.1 0.6 0.17 11.1 0.4 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-C3HC4_2 PF13923.1 EDO16241.1 - 0.17 11.9 12.4 0.29 11.1 8.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EDO16241.1 - 0.2 11.6 7.0 0.43 10.6 4.9 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EDO16241.1 - 0.62 9.8 6.4 1.2 8.9 4.4 1.5 1 0 0 1 1 1 0 PHD-finger Malate_synthase PF01274.17 EDO16242.1 - 2.2e-213 709.0 0.0 2.6e-213 708.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF1903 PF08991.5 EDO16243.1 - 5.4e-07 29.6 5.5 9.1e-07 28.9 3.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EDO16243.1 - 6.6e-06 25.9 8.6 1.1e-05 25.2 5.9 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EDO16243.1 - 0.04 13.9 3.6 0.063 13.3 2.5 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 UPF0203 PF05254.7 EDO16243.1 - 0.19 11.5 5.5 0.54 10.1 3.8 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Ribosomal_L35p PF01632.14 EDO16244.1 - 8.7e-07 28.7 5.7 1.1e-06 28.3 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 DSPc PF00782.15 EDO16245.1 - 5.1e-11 42.2 0.6 2e-10 40.3 0.0 2.2 2 1 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDO16245.1 - 9.2e-05 21.8 1.4 0.00011 21.5 0.0 1.9 2 1 1 3 3 3 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EDO16245.1 - 0.008 16.4 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EDO16245.1 - 0.0092 16.0 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF59 PF01883.14 EDO16246.1 - 7.2e-06 25.9 0.1 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF59 Tom22 PF04281.8 EDO16247.1 - 4.2e-38 129.9 0.3 4.7e-38 129.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 ADH_zinc_N PF00107.21 EDO16248.1 - 3.1e-14 52.6 0.0 5.5e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO16248.1 - 5.9e-06 26.0 0.2 0.00013 21.6 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EDO16248.1 - 0.059 14.2 0.0 0.14 13.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FKBP_C PF00254.23 EDO16250.1 - 1.7e-32 111.3 0.0 2e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pro_racemase PF05544.6 EDO16250.1 - 0.039 12.7 0.0 0.046 12.5 0.0 1.0 1 0 0 1 1 1 0 Proline racemase Eaf7 PF07904.8 EDO16251.1 - 9.2e-33 112.0 1.9 9.2e-33 112.0 1.4 3.6 3 0 0 3 3 3 1 Chromatin modification-related protein EAF7 ASFV_J13L PF05568.6 EDO16251.1 - 0.012 15.1 0.4 3.7 7.0 0.1 2.6 1 1 1 2 2 2 0 African swine fever virus J13L protein S4 PF01479.20 EDO16252.1 - 2.4e-17 62.0 0.0 6.1e-17 60.7 0.0 1.8 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EDO16252.1 - 0.0063 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain CAP_N PF01213.14 EDO16253.1 - 1.2e-103 346.6 5.3 1.6e-103 346.2 3.7 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EDO16253.1 - 7.9e-61 204.0 1.6 7.9e-61 204.0 1.1 1.8 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EDO16253.1 - 0.08 12.3 0.9 0.17 11.2 0.6 1.5 1 0 0 1 1 1 0 Tubulin binding cofactor C DUF2422 PF10337.4 EDO16253.1 - 0.16 10.7 0.1 0.32 9.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Ribosomal_60s PF00428.14 EDO16253.1 - 1.5 9.2 7.8 2.3 8.6 0.9 2.7 1 1 0 2 2 2 0 60s Acidic ribosomal protein DUF1446 PF07287.6 EDO16254.1 - 0.019 13.4 0.0 0.032 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1446) SF3b10 PF07189.6 EDO16255.1 - 9.5e-28 95.8 0.3 1.1e-27 95.5 0.2 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) C2 PF00168.25 EDO16256.1 - 0.00088 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain Mononeg_mRNAcap PF14318.1 EDO16256.1 - 0.051 12.5 3.4 0.1 11.5 2.4 1.4 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V PGA2 PF07543.7 EDO16258.1 - 1.7e-13 50.5 12.8 8.3e-12 45.0 8.9 2.1 1 1 0 1 1 1 1 Protein trafficking PGA2 DUF2852 PF11014.3 EDO16258.1 - 0.0045 16.9 0.7 0.0055 16.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2852) DnaG_DnaB_bind PF08278.6 EDO16258.1 - 0.029 14.5 1.9 0.039 14.1 1.3 1.1 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding DUF927 PF06048.6 EDO16258.1 - 0.034 13.4 0.1 0.036 13.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF927) NHase_beta PF02211.10 EDO16258.1 - 0.045 13.4 0.1 0.055 13.1 0.1 1.1 1 0 0 1 1 1 0 Nitrile hydratase beta subunit DUF2361 PF10153.4 EDO16258.1 - 0.058 13.5 5.2 0.071 13.2 3.6 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) T4_neck-protein PF11649.3 EDO16258.1 - 0.061 12.5 0.4 0.079 12.2 0.3 1.1 1 0 0 1 1 1 0 Virus neck protein DivIC PF04977.10 EDO16258.1 - 0.099 12.1 5.8 0.72 9.3 0.5 2.1 2 0 0 2 2 2 0 Septum formation initiator FLO_LFY PF01698.11 EDO16258.1 - 0.56 8.9 4.7 0.64 8.8 3.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1049 PF06305.6 EDO16258.1 - 6.7 6.2 6.6 9.3 5.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Phage_Gp23 PF10669.4 EDO16258.1 - 9 6.4 9.4 31 4.7 6.5 1.7 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Acyltransferase PF01553.16 EDO16260.1 - 0.00027 20.3 0.0 0.0016 17.8 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.16 EDO16261.1 - 7.2e-13 48.1 0.2 1.9e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 Acyltransferase Kinesin PF00225.18 EDO16262.1 - 4.2e-100 334.7 4.2 4.2e-100 334.7 2.9 1.9 2 1 1 3 3 3 1 Kinesin motor domain Fez1 PF06818.10 EDO16262.1 - 0.00077 19.5 20.2 0.00077 19.5 14.0 2.6 1 1 1 2 2 2 1 Fez1 NPV_P10 PF05531.7 EDO16262.1 - 0.0089 16.2 3.1 0.0089 16.2 2.2 5.2 4 1 2 6 6 6 2 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EDO16262.1 - 2.4 7.9 23.3 2.4 7.9 3.1 4.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Rrp15p PF07890.7 EDO16263.1 - 3.9e-31 107.7 14.4 3.9e-31 107.7 10.0 1.7 3 0 0 3 3 3 1 Rrp15p GET2 PF08690.5 EDO16263.1 - 0.031 13.5 1.0 0.031 13.5 0.7 2.2 2 1 0 2 2 2 0 GET complex subunit GET2 DUF2018 PF09442.5 EDO16263.1 - 0.086 13.4 4.6 0.9 10.1 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF2018) DUF3035 PF11233.3 EDO16263.1 - 0.15 12.1 1.5 0.3 11.1 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) DUF3958 PF13125.1 EDO16263.1 - 0.24 11.3 5.1 2.3 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Pet20 PF08692.5 EDO16263.1 - 0.58 10.0 3.8 4.6 7.1 0.2 2.6 2 0 0 2 2 2 0 Mitochondrial protein Pet20 Metallophos PF00149.23 EDO16264.1 - 2e-37 128.5 0.9 2.3e-37 128.3 0.1 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 EDO16264.1 - 5.9e-24 83.5 5.8 1.6e-20 72.5 0.8 3.0 3 1 1 4 4 3 2 TPR repeat TPR_1 PF00515.23 EDO16264.1 - 7.4e-16 57.0 5.1 6.6e-08 31.8 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO16264.1 - 1.5e-14 52.6 1.1 4.5e-06 26.1 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat PPP5 PF08321.7 EDO16264.1 - 6.8e-10 38.8 0.1 5.2e-07 29.6 0.0 3.1 2 1 0 2 2 2 1 PPP5 TPR repeat region TPR_17 PF13431.1 EDO16264.1 - 2.7e-07 30.2 3.6 0.00034 20.5 0.4 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDO16264.1 - 1.7e-06 27.7 0.0 0.016 15.0 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDO16264.1 - 2.3e-06 27.8 2.4 5.2e-06 26.7 0.6 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO16264.1 - 1.2e-05 24.7 4.4 0.014 15.1 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO16264.1 - 3.7e-05 24.2 0.5 0.024 15.3 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO16264.1 - 8e-05 22.4 1.3 0.0014 18.4 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO16264.1 - 0.00019 21.8 0.3 0.59 10.9 0.0 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO16264.1 - 0.00033 20.2 0.1 0.0033 17.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO16264.1 - 0.001 19.1 1.4 0.0045 17.0 1.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EDO16264.1 - 0.028 14.2 0.2 0.082 12.7 0.2 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Metallophos_2 PF12850.2 EDO16264.1 - 0.032 14.0 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain NBP1 PF08537.5 EDO16264.1 - 0.063 12.4 0.1 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 ATP-synt_DE_N PF02823.11 EDO16265.1 - 3e-12 46.1 0.0 4.1e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain SET PF00856.23 EDO16266.1 - 2.3e-05 24.7 0.1 0.00069 19.9 0.0 3.2 2 1 0 2 2 2 1 SET domain Astro_capsid PF03115.9 EDO16266.1 - 1.9 6.6 3.2 2.5 6.2 2.2 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Ribosomal_L4 PF00573.17 EDO16267.1 - 4.7e-47 159.8 2.5 7.5e-47 159.2 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EDO16267.1 - 1.2e-30 105.1 4.1 1.7e-29 101.4 0.9 2.5 2 0 0 2 2 2 2 60S ribosomal protein L4 C-terminal domain Sld5 PF05916.6 EDO16268.1 - 3.8e-13 49.6 1.0 6.2e-13 48.9 0.7 1.3 1 0 0 1 1 1 1 GINS complex protein PIF1 PF05970.9 EDO16268.1 - 0.00035 19.6 0.2 0.013 14.4 0.0 2.0 1 1 1 2 2 2 2 PIF1-like helicase DUF3016 PF11454.3 EDO16268.1 - 0.07 12.7 0.5 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3016) Syntaxin_2 PF14523.1 EDO16268.1 - 0.93 9.5 6.4 2.3 8.3 0.1 2.5 1 1 1 2 2 2 0 Syntaxin-like protein DUF2262 PF10020.4 EDO16269.1 - 0.39 10.8 16.8 21 5.2 8.7 3.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2262) PNPOx_C PF10590.4 EDO16270.1 - 8.8e-21 73.1 2.4 1.8e-20 72.1 1.7 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EDO16270.1 - 4.1e-11 42.7 0.0 5.8e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 EDO16270.1 - 0.05 13.9 0.1 0.092 13.0 0.0 1.6 1 1 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Prefoldin PF02996.12 EDO16271.1 - 2e-37 127.4 1.9 3.8e-37 126.5 1.3 1.5 1 0 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.4 EDO16271.1 - 0.027 14.3 8.0 0.18 11.6 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin-6_N PF09177.6 EDO16271.1 - 0.041 14.2 4.1 0.64 10.4 0.2 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Matrilin_ccoil PF10393.4 EDO16271.1 - 0.048 13.0 0.5 5.6 6.4 0.1 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin TMPIT PF07851.8 EDO16271.1 - 0.11 11.5 5.3 0.016 14.2 1.2 1.4 2 0 0 2 2 2 0 TMPIT-like protein Tropomyosin PF00261.15 EDO16271.1 - 0.36 9.8 9.3 0.35 9.9 1.6 2.4 2 1 0 2 2 2 0 Tropomyosin Lebercilin PF15619.1 EDO16271.1 - 0.83 9.0 9.8 3.6 6.9 0.5 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin_2 PF01920.15 EDO16271.1 - 0.87 9.3 10.4 4.9 6.9 0.9 3.0 1 1 1 2 2 2 0 Prefoldin subunit TSC22 PF01166.13 EDO16271.1 - 1.6 8.7 6.1 1.9 8.5 0.8 2.6 2 0 0 2 2 2 0 TSC-22/dip/bun family BBP1_C PF15272.1 EDO16271.1 - 4 6.9 10.4 0.4 10.2 2.9 2.0 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal PHB_acc PF05233.8 EDO16273.1 - 0.002 17.8 0.0 2.6 7.8 0.0 2.7 2 0 0 2 2 2 2 PHB accumulation regulatory domain PRP38 PF03371.10 EDO16275.1 - 2e-52 177.3 3.0 2.5e-52 176.9 2.1 1.0 1 0 0 1 1 1 1 PRP38 family Smg4_UPF3 PF03467.10 EDO16276.1 - 8.9e-19 68.1 5.3 8.9e-19 68.1 3.7 2.4 1 1 0 2 2 2 1 Smg-4/UPF3 family PCI PF01399.22 EDO16277.1 - 2.7e-05 24.4 0.1 8.1e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 PCI domain Metallophos PF00149.23 EDO16278.1 - 2.1e-43 148.0 0.2 2.6e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDO16278.1 - 0.001 18.9 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DIL PF01843.14 EDO16278.1 - 0.027 14.3 0.1 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 DIL domain E1_DerP2_DerF2 PF02221.10 EDO16279.1 - 7.6e-28 97.4 0.1 8.8e-28 97.2 0.1 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EDO16279.1 - 9.6e-05 22.4 0.0 0.00012 22.1 0.0 1.2 1 0 0 1 1 1 1 ML-like domain DUF4625 PF15418.1 EDO16279.1 - 0.029 14.5 0.0 0.062 13.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4625) TOBE_2 PF08402.5 EDO16279.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 TOBE domain RPAP2_Rtr1 PF04181.8 EDO16280.1 - 1.8e-20 72.7 0.2 3.8e-20 71.7 0.1 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family TraB PF01963.12 EDO16280.1 - 0.085 12.2 0.7 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 TraB family Pox_int_trans PF05718.7 EDO16280.1 - 0.089 11.2 0.0 0.19 10.1 0.0 1.5 2 0 0 2 2 2 0 Poxvirus intermediate transcription factor CYTL1 PF15153.1 EDO16281.1 - 0.035 13.8 1.6 1.3 8.7 0.0 2.9 2 1 0 2 2 2 0 Cytokine-like protein 1 Osmo_CC PF08946.5 EDO16281.1 - 2.2 8.3 8.4 0.34 10.9 0.4 3.3 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Ribosomal_S15 PF00312.17 EDO16282.1 - 2.2e-23 81.7 0.1 9.5e-23 79.7 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S13_N PF08069.7 EDO16282.1 - 1.8e-20 72.5 0.2 3.8e-20 71.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Cofilin_ADF PF00241.15 EDO16283.1 - 5e-08 32.8 0.0 7e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Neisseria_TspB PF05616.8 EDO16283.1 - 0.021 13.2 0.1 0.028 12.7 0.1 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Cys_Met_Meta_PP PF01053.15 EDO16283.1 - 0.11 10.8 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme GDI PF00996.13 EDO16284.1 - 1.9e-210 698.7 0.2 2.5e-210 698.3 0.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor LSM PF01423.17 EDO16285.1 - 2.3e-17 62.2 0.2 2.9e-17 61.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO16285.1 - 0.065 13.1 0.0 0.076 12.9 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Aha1_N PF09229.6 EDO16286.1 - 1.5e-38 131.7 2.9 2.1e-38 131.2 2.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Sugar_tr PF00083.19 EDO16287.1 - 1.2e-141 472.3 28.9 1.4e-141 472.1 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO16287.1 - 1.2e-31 109.7 32.0 4.1e-31 107.9 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EDO16287.1 - 1.6e-06 26.6 2.4 1.6e-06 26.6 1.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EDO16287.1 - 0.0012 17.0 0.8 0.0012 17.0 0.6 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector Lig_chan PF00060.21 EDO16287.1 - 0.5 10.0 11.9 0.34 10.6 0.1 3.8 3 1 0 3 3 3 0 Ligand-gated ion channel DUF1673 PF07895.6 EDO16287.1 - 3.2 7.2 12.2 0.47 9.9 1.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) HlyIII PF03006.15 EDO16289.1 - 1.8e-46 158.3 22.1 2.2e-46 158.0 15.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related PalH PF08733.5 EDO16289.1 - 0.12 11.1 10.2 0.042 12.7 4.9 1.6 1 1 0 1 1 1 0 PalH/RIM21 DUF4231 PF14015.1 EDO16289.1 - 0.16 11.9 1.5 4.4 7.3 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF2815 PF10991.3 EDO16290.1 - 0.034 13.6 0.4 0.055 12.9 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) CDC45 PF02724.9 EDO16290.1 - 0.12 10.3 4.5 0.18 9.8 3.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.6 EDO16290.1 - 0.4 10.5 14.7 0.022 14.6 6.5 1.5 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) Sld5 PF05916.6 EDO16291.1 - 5.1e-21 74.9 0.1 1.4e-20 73.6 0.1 1.8 1 0 0 1 1 1 1 GINS complex protein Methyltransf_23 PF13489.1 EDO16292.1 - 8.9e-24 84.0 0.0 1.4e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO16292.1 - 2.3e-20 72.7 0.0 3.3e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO16292.1 - 1.8e-17 63.9 0.0 6.9e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO16292.1 - 3.2e-17 62.7 0.0 5.6e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO16292.1 - 1.6e-16 60.5 0.0 2.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO16292.1 - 3e-11 42.9 0.0 4.2e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 EDO16292.1 - 4.2e-10 39.9 0.0 7.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDO16292.1 - 2.4e-08 33.4 0.0 3.6e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 EDO16292.1 - 1.8e-07 30.7 0.0 2.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 EDO16292.1 - 3.5e-07 29.5 0.0 5.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EDO16292.1 - 4e-07 30.0 0.0 1.2e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO16292.1 - 5.4e-07 29.3 0.0 1.1e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 EDO16292.1 - 6.2e-07 28.5 0.0 1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.9 EDO16292.1 - 4.9e-06 26.0 0.0 9.5e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EDO16292.1 - 3.2e-05 23.1 0.0 4.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EDO16292.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EDO16292.1 - 0.0014 17.7 0.0 0.45 9.5 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase Spermine_synth PF01564.12 EDO16292.1 - 0.0099 14.8 0.0 0.02 13.8 0.0 1.5 1 1 0 1 1 1 1 Spermine/spermidine synthase CheR PF01739.13 EDO16292.1 - 0.013 14.7 0.0 4.5 6.4 0.0 2.5 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_9 PF08003.6 EDO16292.1 - 0.026 13.2 0.0 0.041 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.7 EDO16292.1 - 0.028 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_10 PF05971.7 EDO16292.1 - 0.083 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF890) YL1 PF05764.8 EDO16293.1 - 1.7e-49 168.6 75.0 1.7e-49 168.6 52.0 4.5 2 2 1 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 EDO16293.1 - 4.5e-13 48.5 0.8 7.3e-13 47.8 0.5 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain UvrD_C PF13361.1 EDO16295.1 - 5.5e-39 134.6 4.9 5.5e-39 134.6 3.4 2.0 2 1 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EDO16295.1 - 7.5e-30 104.2 1.5 2e-14 53.6 0.0 2.8 2 2 1 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 EDO16295.1 - 9e-09 34.9 0.0 2.1e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EDO16295.1 - 3.9e-08 33.1 0.4 2.1e-07 30.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EDO16295.1 - 3.9e-05 23.2 0.0 0.19 11.1 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EDO16295.1 - 0.00014 21.9 0.0 0.0052 16.9 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_14 PF13173.1 EDO16295.1 - 0.0048 16.7 0.8 0.84 9.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain Resolvase PF00239.16 EDO16295.1 - 0.052 13.4 0.0 0.22 11.3 0.0 2.1 2 1 0 3 3 3 0 Resolvase, N terminal domain Vps52 PF04129.7 EDO16296.1 - 3.7e-142 474.4 20.8 4.5e-142 474.1 14.4 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Spectrin PF00435.16 EDO16296.1 - 0.048 13.9 0.1 0.22 11.8 0.1 2.2 1 0 0 1 1 1 0 Spectrin repeat tRNA_m1G_MT PF01746.16 EDO16297.1 - 1e-28 100.2 0.2 1.7e-28 99.4 0.1 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase VSG_B PF13206.1 EDO16297.1 - 0.15 11.1 2.5 0.24 10.5 1.7 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain Vma12 PF11712.3 EDO16297.1 - 0.2 11.3 1.2 0.39 10.4 0.8 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase HALZ PF02183.13 EDO16299.1 - 0.87 9.3 19.1 0.14 11.8 0.8 4.7 3 1 1 4 4 4 0 Homeobox associated leucine zipper MutS_V PF00488.16 EDO16300.1 - 2.6e-97 324.8 0.1 4.7e-97 324.0 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDO16300.1 - 3.2e-36 125.0 1.9 7.2e-35 120.6 0.0 2.9 2 1 1 3 3 3 1 MutS domain III MutS_II PF05188.12 EDO16300.1 - 5.6e-20 71.7 0.1 5.6e-20 71.7 0.1 2.7 4 0 0 4 4 4 1 MutS domain II MutS_IV PF05190.13 EDO16300.1 - 7.9e-18 64.4 0.9 7.9e-18 64.4 0.6 3.3 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.15 EDO16300.1 - 4.3e-10 39.6 0.2 4e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 MutS domain I Suc_Fer-like PF06999.7 EDO16301.1 - 8.2e-60 202.6 0.0 1e-59 202.3 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-PARP PF00645.13 EDO16301.1 - 0.079 13.2 3.2 0.36 11.1 2.2 2.0 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region RibD_C PF01872.12 EDO16302.1 - 1.5e-38 132.4 0.0 1.7e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain DUF221 PF02714.10 EDO16303.1 - 8.5e-99 330.4 20.6 1.6e-98 329.6 14.3 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EDO16303.1 - 1.9e-38 131.4 3.5 1.9e-38 131.4 2.5 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EDO16303.1 - 4.9e-28 96.8 0.0 1.4e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EDO16303.1 - 1.1e-09 38.6 1.8 2.4e-09 37.5 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) ZZ PF00569.12 EDO16304.1 - 1.6e-07 30.7 9.5 3.8e-07 29.5 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type DUF3795 PF12675.2 EDO16304.1 - 0.14 12.3 10.0 0.25 11.5 6.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) RasGAP PF00616.14 EDO16305.1 - 1.1e-37 129.5 3.5 1.6e-37 129.1 0.5 2.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RNase_T PF00929.19 EDO16306.1 - 2.2e-29 102.8 0.2 5.7e-29 101.5 0.0 1.7 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EDO16306.1 - 2.3e-05 23.9 0.0 6.6e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease RBD PF02196.10 EDO16307.1 - 0.00018 21.2 0.0 0.00058 19.5 0.0 1.8 1 0 0 1 1 1 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.3 EDO16307.1 - 0.0018 18.1 4.0 0.0034 17.2 0.1 3.1 3 0 0 3 3 3 1 GLUT4 regulating protein TUG Brix PF04427.13 EDO16308.1 - 6.2e-40 136.8 0.7 8e-40 136.5 0.5 1.1 1 0 0 1 1 1 1 Brix domain DUF468 PF04318.7 EDO16308.1 - 0.0064 17.0 0.5 0.027 15.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF468) DUF336 PF03928.9 EDO16309.1 - 3e-20 72.3 0.0 3.9e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) LRR_1 PF00560.28 EDO16310.1 - 0.14 12.2 0.2 0.28 11.3 0.1 1.7 1 1 0 1 1 1 0 Leucine Rich Repeat Rabaptin PF03528.10 EDO16312.1 - 0.19 11.6 3.4 0.48 10.3 2.6 1.4 2 0 0 2 2 2 0 Rabaptin GFO_IDH_MocA PF01408.17 EDO16315.1 - 5.9e-07 30.0 0.0 9.2e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EDO16315.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain zf-HIT PF04438.11 EDO16316.1 - 2.2e-11 43.1 12.0 4e-11 42.3 8.3 1.5 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.6 EDO16316.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-Mss51 PF13824.1 EDO16316.1 - 0.018 14.9 3.5 0.035 13.9 2.5 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EDO16316.1 - 0.046 13.5 8.7 0.09 12.6 6.1 1.5 1 0 0 1 1 1 0 MYND finger DUF1610 PF07754.6 EDO16316.1 - 0.058 13.5 3.0 0.13 12.4 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) PolC_DP2 PF03833.8 EDO16316.1 - 0.2 9.2 3.4 0.2 9.2 2.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 CPSF_A PF03178.10 EDO16317.1 - 1.3e-56 192.0 2.9 3.7e-56 190.5 0.3 2.4 2 0 0 2 2 2 1 CPSF A subunit region BBS2_N PF14781.1 EDO16317.1 - 0.87 9.2 5.7 1 8.9 0.2 3.4 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal Myc_N PF01056.13 EDO16317.1 - 0.89 8.6 8.1 5.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Myc amino-terminal region DUF997 PF06196.7 EDO16318.1 - 1.6 8.2 8.5 4.1 6.9 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Ly49 PF08391.5 EDO16319.1 - 0.058 13.5 0.7 0.058 13.5 0.5 3.0 2 1 1 3 3 3 0 Ly49-like protein, N-terminal region Sedlin_N PF04628.8 EDO16320.1 - 1.1e-14 54.4 0.9 1.4e-14 54.0 0.6 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Propep_M14 PF02244.11 EDO16320.1 - 0.063 12.9 0.1 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Carboxypeptidase activation peptide FAD_binding_2 PF00890.19 EDO16321.1 - 3e-70 237.1 0.0 3.4e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EDO16321.1 - 3.9e-10 39.9 0.0 0.00083 19.2 0.0 3.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO16321.1 - 3.9e-06 26.0 0.6 0.0028 16.6 0.0 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EDO16321.1 - 8.7e-06 25.9 0.1 0.00011 22.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO16321.1 - 1.7e-05 24.7 0.1 4.9e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EDO16321.1 - 0.00035 19.7 0.5 0.056 12.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.1 EDO16321.1 - 0.006 16.3 0.1 0.033 13.9 0.1 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EDO16321.1 - 0.062 12.2 0.2 2.6 6.8 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EDO16321.1 - 0.064 12.3 0.2 0.2 10.6 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDO16321.1 - 0.14 11.1 1.2 0.16 11.0 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EDO16321.1 - 0.24 9.7 4.4 0.84 8.0 0.6 2.7 2 1 0 2 2 2 0 HI0933-like protein Beta_elim_lyase PF01212.16 EDO16322.1 - 1.4e-73 247.5 0.0 1.8e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EDO16322.1 - 0.0003 19.8 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II YL1_C PF08265.6 EDO16323.1 - 6.8e-15 54.3 0.4 6.8e-15 54.3 0.3 1.6 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Nramp PF01566.13 EDO16324.1 - 4.2e-88 295.5 11.9 1.1e-87 294.1 8.2 1.6 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein fn3 PF00041.16 EDO16325.1 - 0.012 15.7 2.8 5.8 7.1 1.0 3.0 2 0 0 2 2 2 0 Fibronectin type III domain DUF1664 PF07889.7 EDO16325.1 - 4.7 7.0 13.5 0.42 10.4 2.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GDA1_CD39 PF01150.12 EDO16326.1 - 3.1e-110 368.6 0.0 3.9e-110 368.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family NAD_kinase PF01513.16 EDO16327.1 - 5.1e-80 268.3 0.0 6.6e-80 267.9 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase 2C_adapt PF08793.5 EDO16327.1 - 0.0053 16.6 0.1 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 2-cysteine adaptor domain DAGK_cat PF00781.19 EDO16327.1 - 0.14 11.5 0.0 0.35 10.2 0.0 1.7 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain AHS2 PF02626.10 EDO16327.1 - 0.17 11.1 0.1 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Allophanate hydrolase subunit 2 Glyco_hydro_16 PF00722.16 EDO16328.1 - 2.6e-42 144.2 7.4 6.4e-42 142.9 5.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF515 PF04415.7 EDO16328.1 - 3.3 5.8 17.6 4.6 5.3 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Chitin_bind_1 PF00187.14 EDO16328.1 - 5.9 6.9 11.3 14 5.7 7.8 1.6 1 0 0 1 1 1 0 Chitin recognition protein Cytochrom_C PF00034.16 EDO16329.1 - 7.4e-10 39.5 0.0 1.2e-09 38.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EDO16329.1 - 2.4e-07 30.8 1.9 2.6e-06 27.4 1.3 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EDO16329.1 - 0.034 13.6 0.3 0.086 12.2 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c-550 domain HAD_2 PF13419.1 EDO16331.1 - 1.1e-17 64.7 0.0 1.5e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase eIF-5a PF01287.15 EDO16332.1 - 8.8e-28 96.0 0.7 1.4e-27 95.4 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EDO16332.1 - 0.0014 18.2 0.3 0.0025 17.4 0.2 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EDO16332.1 - 0.0037 17.1 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain NifU_N PF01592.11 EDO16333.1 - 1.3e-53 180.2 0.1 1.6e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Glyco_hydro_98M PF08306.6 EDO16333.1 - 0.11 11.2 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 RNA_pol_Rpb8 PF03870.10 EDO16334.1 - 3.9e-47 159.9 0.1 4.4e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 DUF2407_C PF13373.1 EDO16335.1 - 2.2e-46 157.2 1.8 3.7e-46 156.5 1.3 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EDO16335.1 - 2.4e-18 66.0 0.1 5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Zn_clus PF00172.13 EDO16336.1 - 0.00012 21.8 8.5 0.00029 20.6 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CtaG_Cox11 PF04442.9 EDO16337.1 - 6.1e-58 194.9 0.0 9.2e-58 194.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Cag12 PF13117.1 EDO16338.1 - 0.0036 17.2 0.5 0.14 12.0 0.1 2.2 2 0 0 2 2 2 2 Cag pathogenicity island protein Cag12 RFC1 PF08519.7 EDO16339.1 - 1.4e-60 203.5 0.9 5.4e-59 198.4 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 EDO16339.1 - 2.7e-13 50.2 0.1 1e-12 48.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 EDO16339.1 - 1.8e-11 44.0 0.0 8.9e-11 41.7 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.10 EDO16339.1 - 3.2e-07 29.4 0.1 0.0001 21.1 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EDO16339.1 - 4.3e-06 26.9 0.0 2.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO16339.1 - 1.3e-05 25.9 0.0 7e-05 23.6 0.0 2.3 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDO16339.1 - 3.4e-05 23.0 0.6 6.5e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus PTCB-BRCT PF12738.2 EDO16339.1 - 0.00029 20.6 0.2 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain AAA_16 PF13191.1 EDO16339.1 - 0.0007 19.6 0.0 0.016 15.2 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 EDO16339.1 - 0.0015 18.4 0.0 0.0044 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO16339.1 - 0.0015 18.8 0.0 0.0072 16.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EDO16339.1 - 0.0017 18.4 0.0 0.0061 16.7 0.0 2.1 1 1 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 EDO16339.1 - 0.003 17.4 0.0 0.0098 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO16339.1 - 0.0044 16.7 0.1 0.027 14.2 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EDO16339.1 - 0.082 12.6 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GRAB PF10375.4 EDO16340.1 - 3.5e-07 29.6 0.8 9.5e-07 28.2 0.5 1.8 1 0 0 1 1 1 1 GRIP-related Arf-binding domain IncA PF04156.9 EDO16340.1 - 5.8e-06 26.0 57.6 0.031 13.8 11.7 3.6 1 1 1 2 2 2 2 IncA protein Spc7 PF08317.6 EDO16340.1 - 2.3e-05 23.2 55.2 0.0018 17.0 15.4 2.3 1 1 1 2 2 2 2 Spc7 kinetochore protein GAS PF13851.1 EDO16340.1 - 0.00015 21.0 62.8 0.0021 17.2 10.3 4.2 1 1 2 4 4 4 2 Growth-arrest specific micro-tubule binding DUF2353 PF09789.4 EDO16340.1 - 0.0014 17.9 31.6 0.0014 17.9 21.9 2.8 2 1 1 3 3 3 2 Uncharacterized coiled-coil protein (DUF2353) Filament PF00038.16 EDO16340.1 - 0.0024 17.4 49.1 0.29 10.5 18.4 3.0 1 1 1 2 2 2 2 Intermediate filament protein DUF1664 PF07889.7 EDO16340.1 - 0.0032 17.2 5.4 0.0032 17.2 3.8 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 EDO16340.1 - 0.0036 17.0 17.9 0.0036 17.0 12.4 6.0 3 2 2 6 6 6 3 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EDO16340.1 - 0.004 17.0 27.0 0.004 17.0 18.7 4.8 2 1 3 5 5 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin PF00804.20 EDO16340.1 - 0.01 15.9 17.1 0.01 15.9 11.8 4.3 1 1 3 4 4 4 0 Syntaxin Lebercilin PF15619.1 EDO16340.1 - 0.026 13.9 53.9 1.9 7.8 0.0 3.7 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.1 EDO16340.1 - 0.028 12.9 52.2 0.0083 14.6 14.1 2.2 1 1 1 2 2 2 0 AAA domain APG6 PF04111.7 EDO16340.1 - 0.033 13.2 58.9 0.21 10.5 19.2 3.5 1 1 2 3 3 3 0 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 EDO16340.1 - 0.038 11.7 60.2 0.1 10.2 23.2 2.5 1 1 1 2 2 2 0 Myosin tail TPR_MLP1_2 PF07926.7 EDO16340.1 - 0.091 12.5 57.7 0.18 11.5 12.5 4.1 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein FUSC PF04632.7 EDO16340.1 - 0.16 10.3 2.9 0.18 10.1 1.1 1.6 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF3584 PF12128.3 EDO16340.1 - 0.29 8.4 43.9 0.83 6.8 15.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Rab5-bind PF09311.6 EDO16340.1 - 0.61 9.9 49.1 0.69 9.7 9.1 3.8 1 1 1 2 2 2 0 Rabaptin-like protein ATG16 PF08614.6 EDO16340.1 - 0.76 9.5 57.3 0.87 9.3 14.2 3.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 EDO16340.1 - 0.84 8.7 26.6 0.054 12.6 9.3 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 EDO16340.1 - 1.2 8.8 55.7 0.5 10.1 14.3 4.3 2 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding DUF4164 PF13747.1 EDO16340.1 - 1.4 9.0 39.6 0.079 13.1 5.3 5.2 1 1 5 6 6 6 0 Domain of unknown function (DUF4164) Laminin_II PF06009.7 EDO16340.1 - 2.4 7.9 42.7 1.2 8.8 7.6 4.7 1 1 3 4 4 4 0 Laminin Domain II ADIP PF11559.3 EDO16340.1 - 2.9 7.7 56.1 0.38 10.6 10.2 4.5 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding WEMBL PF05701.6 EDO16340.1 - 5.6 5.3 57.2 1.2 7.4 4.7 3.4 1 1 2 3 3 3 0 Weak chloroplast movement under blue light DUF342 PF03961.8 EDO16340.1 - 6.9 4.9 50.6 1.8 6.8 6.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 EDO16340.1 - 8.6 6.4 47.7 2.1 8.4 10.7 4.6 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family YqeY PF09424.5 EDO16341.1 - 2.8e-21 75.8 1.8 3.4e-21 75.5 1.2 1.1 1 0 0 1 1 1 1 Yqey-like protein DUF3164 PF11363.3 EDO16341.1 - 0.016 14.5 0.3 0.028 13.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3164) Pox_A3L PF05288.6 EDO16341.1 - 0.026 14.2 0.3 0.084 12.6 0.2 1.9 1 0 0 1 1 1 0 Poxvirus A3L Protein DUF2457 PF10446.4 EDO16342.1 - 0.61 8.7 5.9 0.96 8.0 4.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Asp PF00026.18 EDO16343.1 - 9.4e-21 74.3 0.1 1.7e-19 70.2 0.0 2.6 2 1 0 2 2 2 1 Eukaryotic aspartyl protease Sec23_trunk PF04811.10 EDO16344.1 - 8.2e-57 192.3 0.3 1.1e-56 191.9 0.2 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 EDO16344.1 - 2.1e-14 52.7 4.8 4.4e-14 51.7 3.3 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 EDO16345.1 - 6.6e-24 83.3 2.0 7.3e-24 83.1 0.4 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EDO16345.1 - 3.3e-10 40.3 0.0 7e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EDO16345.1 - 0.00013 21.5 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Pal1 PF08316.6 EDO16346.1 - 6e-57 192.0 1.7 6e-57 192.0 1.2 3.5 3 1 0 3 3 3 1 Pal1 cell morphology protein Sod_Fe_C PF02777.13 EDO16347.1 - 7.4e-10 38.6 0.6 0.0012 18.6 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sugar_tr PF00083.19 EDO16348.1 - 1.1e-162 541.7 31.2 1.2e-162 541.5 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO16348.1 - 9.6e-26 90.3 31.1 4.5e-22 78.2 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_1d PF00750.14 EDO16349.1 - 3.2e-104 348.5 4.6 4.5e-104 348.0 3.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EDO16349.1 - 1.4e-29 102.4 2.4 4.7e-29 100.7 0.1 2.6 3 0 0 3 3 3 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EDO16349.1 - 4.4e-10 39.9 0.1 1.9e-09 37.9 0.0 2.2 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain VD10_N PF08476.5 EDO16349.1 - 0.057 12.9 0.3 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Viral D10 N-terminal Clat_adaptor_s PF01217.15 EDO16350.1 - 8e-56 187.7 1.6 9.7e-56 187.4 1.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DASH_Dad1 PF08649.5 EDO16350.1 - 0.36 10.5 2.1 0.98 9.1 0.4 2.3 1 1 1 2 2 2 0 DASH complex subunit Dad1 RRN7 PF11781.3 EDO16351.1 - 4.5e-10 38.8 0.2 8.8e-10 37.9 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 RNase_H PF00075.19 EDO16352.1 - 0.00029 21.1 0.2 0.024 14.9 0.0 2.2 1 1 1 2 2 2 2 RNase H SpoVIF PF14069.1 EDO16352.1 - 0.024 14.3 2.8 0.1 12.3 0.1 2.4 2 1 0 2 2 2 0 Stage VI sporulation protein F UPF0054 PF02130.12 EDO16352.1 - 0.093 12.0 0.6 0.2 10.9 0.1 1.7 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 DUF2838 PF10998.3 EDO16353.1 - 3.1e-43 146.1 15.4 3.1e-43 146.1 10.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) DivIC PF04977.10 EDO16353.1 - 0.0035 16.8 0.4 0.012 15.1 0.3 1.9 1 0 0 1 1 1 1 Septum formation initiator Kinetocho_Slk19 PF12709.2 EDO16353.1 - 0.0049 16.9 1.5 0.0095 15.9 1.1 1.4 1 0 0 1 1 1 1 Central kinetochore-associated PPR_2 PF13041.1 EDO16354.1 - 1.2e-12 47.5 1.2 6.8e-08 32.3 0.1 2.8 1 1 1 2 2 2 2 PPR repeat family PPR_3 PF13812.1 EDO16354.1 - 5.8e-10 38.6 0.3 0.0016 18.5 0.0 4.3 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.15 EDO16354.1 - 1.1e-07 31.3 0.3 3.5e-05 23.4 0.0 3.1 2 0 0 2 2 2 2 PPR repeat Cgr1 PF03879.9 EDO16355.1 - 2.3e-38 130.7 34.4 2.7e-38 130.4 23.9 1.0 1 0 0 1 1 1 1 Cgr1 family DRY_EERY PF09750.4 EDO16355.1 - 0.14 12.2 6.5 0.17 11.9 4.5 1.2 1 0 0 1 1 1 0 Alternative splicing regulator Atg14 PF10186.4 EDO16355.1 - 5.6 5.8 17.6 5.7 5.7 12.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HIM1 PF08732.5 EDO16356.1 - 1.6e-70 237.7 3.1 1.9e-70 237.4 2.1 1.0 1 0 0 1 1 1 1 HIM1 CENP-O PF09496.5 EDO16357.1 - 9e-22 77.1 0.9 1.8e-21 76.1 0.1 1.9 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DUF4349 PF14257.1 EDO16357.1 - 0.0092 15.2 0.5 0.017 14.3 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) DivIC PF04977.10 EDO16357.1 - 0.026 14.0 1.2 0.096 12.1 0.8 2.0 1 0 0 1 1 1 0 Septum formation initiator Lip_prot_lig_C PF10437.4 EDO16357.1 - 0.048 13.3 2.4 2.5 7.8 0.1 3.1 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Uds1 PF15456.1 EDO16357.1 - 4.1 7.4 7.9 41 4.1 5.5 2.5 1 1 0 1 1 1 0 Up-regulated During Septation Nop10p PF04135.7 EDO16358.1 - 7.6e-22 76.8 0.1 9.4e-22 76.5 0.1 1.2 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Asparaginase PF00710.15 EDO16359.1 - 1.2e-73 247.7 0.0 1.3e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Asparaginase Ribosomal_L19 PF01245.15 EDO16359.1 - 0.17 11.6 0.0 28 4.5 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L19 FAD_binding_1 PF00667.15 EDO16360.1 - 1.5e-69 233.7 0.0 2.3e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EDO16360.1 - 1.5e-27 96.3 0.4 2.7e-27 95.5 0.3 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EDO16360.1 - 1.7e-21 76.7 0.0 4.2e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EDO16360.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain SPOUT_MTase_2 PF14419.1 EDO16360.1 - 0.18 10.9 0.0 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP HAD_2 PF13419.1 EDO16361.1 - 5.7e-14 52.7 0.0 9.4e-14 52.0 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDO16361.1 - 4.2e-07 29.5 0.1 7.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDO16361.1 - 0.00087 19.7 0.0 0.0038 17.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDO16361.1 - 0.0012 19.0 0.0 0.0015 18.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FtsJ PF01728.14 EDO16361.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase RNase_PH PF01138.16 EDO16362.1 - 4.7e-20 72.2 0.0 7.9e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDO16362.1 - 2e-11 43.6 0.0 4.5e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_H2-Ydr279 PF09468.5 EDO16363.1 - 2.8e-60 204.1 11.3 3.3e-60 203.8 7.8 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Rubis-subs-bind PF09273.6 EDO16363.1 - 0.0062 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding ERAP1_C PF11838.3 EDO16364.1 - 0.054 12.7 0.3 0.11 11.7 0.0 1.5 2 0 0 2 2 2 0 ERAP1-like C-terminal domain Inositol_P PF00459.20 EDO16365.1 - 1.7e-62 211.2 0.0 1.9e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.11 EDO16366.1 - 2.3e-38 131.8 30.9 2.3e-38 131.8 21.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO16366.1 - 1.6e-07 30.3 34.1 3.9e-07 28.9 23.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter FSH1 PF03959.8 EDO16367.1 - 1.3e-64 217.5 0.0 1.5e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EDO16367.1 - 1.9e-05 24.4 0.0 2.8e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO16367.1 - 0.00044 20.2 0.0 0.059 13.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDO16367.1 - 0.00045 19.7 0.2 0.1 12.0 0.2 2.6 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Nramp PF01566.13 EDO16368.1 - 2.1e-94 316.2 11.0 2.9e-94 315.8 7.6 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein COX5A PF02284.11 EDO16369.1 - 2.2e-48 162.6 2.3 2.8e-48 162.3 1.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va PAF-AH_p_II PF03403.8 EDO16369.1 - 0.072 11.3 0.1 0.1 10.8 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF4286 PF14114.1 EDO16369.1 - 0.15 12.3 2.4 7.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) Elf1 PF05129.8 EDO16370.1 - 4.7e-31 106.3 2.5 6.1e-31 105.9 1.7 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.14 EDO16370.1 - 0.17 11.8 1.3 0.29 11.0 0.9 1.3 1 0 0 1 1 1 0 Ribosomal L37ae protein family zf-C2H2_6 PF13912.1 EDO16370.1 - 0.21 11.5 0.4 0.21 11.5 0.3 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger CDC45 PF02724.9 EDO16370.1 - 0.54 8.2 4.6 0.58 8.1 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EDO16370.1 - 3.7 5.3 8.7 4.2 5.1 6.0 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L1 PF00687.16 EDO16371.1 - 6.9e-42 143.2 8.8 1.2e-41 142.5 6.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MatE PF01554.13 EDO16372.1 - 4.9e-63 211.5 28.5 4.2e-32 111.0 6.8 2.4 2 0 0 2 2 2 2 MatE PhzC-PhzF PF02567.11 EDO16373.1 - 5.5e-63 212.8 0.0 6.1e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 EDO16373.1 - 0.026 13.3 0.0 0.39 9.4 0.0 2.1 2 0 0 2 2 2 0 Proline racemase DAP_epimerase PF01678.14 EDO16373.1 - 0.038 13.8 0.0 8.4 6.3 0.0 2.6 2 1 0 2 2 2 0 Diaminopimelate epimerase DPPIV_N PF00930.16 EDO16374.1 - 6e-98 327.6 4.8 9.3e-98 327.0 3.3 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EDO16374.1 - 3.4e-53 180.0 1.3 6.1e-53 179.2 0.9 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDO16374.1 - 1.2e-09 38.0 0.0 4.5e-09 36.2 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO16374.1 - 3.9e-05 23.6 0.0 0.00048 20.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDO16374.1 - 0.028 13.8 0.1 9.5 5.5 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EDO16374.1 - 0.046 13.2 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EDO16374.1 - 0.048 12.9 0.1 0.74 9.0 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family PC_rep PF01851.17 EDO16375.1 - 5e-25 86.2 17.1 9.2e-07 28.7 0.1 10.0 10 0 0 10 10 10 6 Proteasome/cyclosome repeat HGTP_anticodon2 PF12745.2 EDO16375.1 - 4.7 6.2 9.9 1.9 7.5 0.1 2.5 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs Myosin_head PF00063.16 EDO16376.1 - 1.9e-227 756.6 27.6 1.9e-227 756.6 19.1 4.7 4 2 0 5 5 5 1 Myosin head (motor domain) IncA PF04156.9 EDO16376.1 - 0.0047 16.5 23.7 0.0047 16.5 16.4 10.0 2 2 7 9 9 9 2 IncA protein Ras PF00071.17 EDO16377.1 - 6.7e-09 35.3 0.7 4.8e-05 22.7 0.1 2.5 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EDO16377.1 - 6.1e-08 33.1 1.0 2.1e-06 28.1 0.7 2.5 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EDO16377.1 - 9.1e-05 21.7 0.3 0.017 14.3 0.0 2.3 1 1 0 2 2 2 2 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDO16377.1 - 0.066 13.1 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Apc1 PF12859.2 EDO16379.1 - 7.8e-15 54.9 0.5 6.3e-14 52.0 0.1 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EDO16379.1 - 0.021 15.0 5.0 48 4.4 0.1 5.7 5 0 0 5 5 5 0 Proteasome/cyclosome repeat PS_Dcarbxylase PF02666.10 EDO16380.1 - 1.5e-73 246.4 0.0 2e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase dCMP_cyt_deam_1 PF00383.17 EDO16381.1 - 9.8e-27 92.5 1.4 1.4e-26 92.0 1.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region FAA_hydrolase PF01557.13 EDO16382.1 - 5.3e-47 160.0 0.0 7.2e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DNA_RNApol_7kD PF03604.8 EDO16383.1 - 1.9e-16 59.1 1.8 2.5e-16 58.8 1.3 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 EDO16383.1 - 0.0031 17.3 0.4 0.0043 16.8 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 EDO16383.1 - 0.0049 16.5 0.2 0.0049 16.5 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 EDO16383.1 - 0.006 16.1 0.7 2.9 7.6 0.1 2.2 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Prok-RING_1 PF14446.1 EDO16383.1 - 0.007 16.0 0.7 0.0092 15.6 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 FYDLN_acid PF09538.5 EDO16383.1 - 0.028 14.9 0.4 0.034 14.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) NCD3G PF07562.9 EDO16383.1 - 0.034 13.8 0.2 0.041 13.5 0.1 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR C1_1 PF00130.17 EDO16383.1 - 0.037 13.7 0.4 0.053 13.2 0.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 EDO16383.1 - 0.061 12.8 0.9 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF951 PF06107.6 EDO16383.1 - 0.063 12.7 1.5 1.5 8.3 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) DUF2197 PF09963.4 EDO16383.1 - 0.063 13.2 2.2 4.9 7.1 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) DUF4428 PF14471.1 EDO16383.1 - 0.065 12.9 1.5 1.3 8.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) DUF2318 PF10080.4 EDO16383.1 - 0.067 12.9 0.1 0.075 12.8 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) FYVE_2 PF02318.11 EDO16383.1 - 0.068 13.0 0.3 0.072 12.9 0.2 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger Gin PF10764.4 EDO16383.1 - 0.12 12.0 0.2 1.4 8.7 0.0 2.2 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin Zn_ribbon_recom PF13408.1 EDO16383.1 - 0.21 11.8 3.2 3.4 8.0 0.5 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L40e PF01020.12 EDO16383.1 - 0.25 10.9 2.5 0.33 10.5 1.7 1.2 1 0 0 1 1 1 0 Ribosomal L40e family Zn-ribbon_8 PF09723.5 EDO16383.1 - 0.36 10.8 3.4 1.2 9.2 2.3 1.8 1 1 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EDO16383.1 - 0.37 10.6 3.0 1.6 8.6 2.4 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EDO16383.1 - 0.61 9.4 2.6 8.2 5.8 2.1 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding Ribosomal_L44 PF00935.14 EDO16383.1 - 1.1 9.3 4.4 11 6.1 0.5 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 zinc_ribbon_5 PF13719.1 EDO16383.1 - 1.1 8.8 3.3 6.6 6.4 2.3 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Cytochrom_C_2 PF01322.15 EDO16384.1 - 8.5 6.9 10.3 8.7 6.9 2.6 2.6 1 1 1 2 2 2 0 Cytochrome C' Molydop_binding PF01568.16 EDO16386.1 - 0.013 15.2 0.3 0.034 13.9 0.2 1.7 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain TFIIA PF03153.8 EDO16386.1 - 1.8 8.3 11.9 2.4 7.9 8.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTP_EFTU PF00009.22 EDO16388.1 - 3.6e-54 183.0 0.0 7.9e-54 181.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EDO16388.1 - 6.1e-14 51.6 0.0 1.9e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDO16388.1 - 2.4e-09 37.1 0.0 7.3e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EDO16388.1 - 7e-09 35.4 0.0 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EDO16388.1 - 6.3e-05 22.5 0.0 0.00017 21.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EDO16388.1 - 0.0051 16.7 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase CENP-T PF15511.1 EDO16388.1 - 1.4 8.1 13.8 2.1 7.4 9.5 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DNA_pol_phi PF04931.8 EDO16388.1 - 1.7 6.3 24.6 2.6 5.7 17.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi IBR PF01485.16 EDO16389.1 - 0.19 11.6 5.2 0.19 11.6 0.7 2.0 1 1 1 2 2 2 0 IBR domain Pox_A3L PF05288.6 EDO16389.1 - 0.42 10.3 2.2 0.61 9.8 1.5 1.3 1 0 0 1 1 1 0 Poxvirus A3L Protein zf-C4_Topoisom PF01396.14 EDO16389.1 - 2.4 7.7 7.4 4.5 6.8 5.1 1.5 1 1 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger Opy2 PF09463.5 EDO16389.1 - 3.9 7.6 8.2 9.5 6.4 5.7 1.7 1 1 0 1 1 1 0 Opy2 protein DNA_ligase_ZBD PF03119.11 EDO16389.1 - 5.8 6.7 6.8 10 5.9 1.4 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Chs3p PF12271.3 EDO16390.1 - 2.6e-94 315.4 22.1 8.9e-94 313.7 15.3 1.7 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit SH PF01445.12 EDO16390.1 - 0.022 14.3 1.6 0.022 14.3 1.1 2.5 3 0 0 3 3 3 0 Viral small hydrophobic protein Ribosomal_L44 PF00935.14 EDO16391.1 - 2.2e-34 117.3 11.1 3.3e-34 116.7 7.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Far-17a_AIG1 PF04750.9 EDO16392.1 - 1.3e-18 66.9 7.5 1.6e-18 66.6 5.2 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein SIR2 PF02146.12 EDO16393.1 - 1.6e-28 99.6 0.0 2.8e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TIP49 PF06068.8 EDO16394.1 - 3.1e-188 625.4 0.4 3.6e-188 625.2 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EDO16394.1 - 1.4e-08 34.9 0.3 8.4e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO16394.1 - 1.4e-08 34.0 1.8 0.00011 21.2 0.0 3.2 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EDO16394.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO16394.1 - 0.0023 17.9 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EDO16394.1 - 0.0052 16.5 0.1 0.021 14.5 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EDO16394.1 - 0.0091 15.1 0.2 0.027 13.5 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EDO16394.1 - 0.014 15.3 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EDO16394.1 - 0.019 14.1 0.1 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 EDO16394.1 - 0.023 13.5 0.0 0.046 12.6 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_5 PF07728.9 EDO16394.1 - 0.03 14.0 0.2 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) CPT PF07931.7 EDO16394.1 - 0.036 13.6 0.0 0.088 12.4 0.0 1.7 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sec1 PF00995.18 EDO16395.1 - 6.8e-145 483.8 6.7 7.8e-145 483.6 4.6 1.0 1 0 0 1 1 1 1 Sec1 family ubiquitin PF00240.18 EDO16397.1 - 6.9e-35 118.2 0.7 1.3e-34 117.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EDO16397.1 - 7.2e-26 89.7 2.1 1.4e-25 88.8 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EDO16397.1 - 1.4e-19 69.5 0.7 1.4e-19 69.5 0.5 1.7 2 1 1 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDO16397.1 - 9.1e-06 25.8 0.3 4.5e-05 23.6 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDO16397.1 - 0.00018 21.2 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDO16397.1 - 0.0009 19.1 0.4 0.0021 17.9 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDO16397.1 - 0.0043 17.2 0.5 0.0057 16.8 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EDO16397.1 - 0.048 13.5 0.5 0.071 12.9 0.4 1.3 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 EDO16397.1 - 0.059 13.4 0.2 0.13 12.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) DUF2207 PF09972.4 EDO16397.1 - 0.07 11.6 1.0 0.079 11.5 0.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plexin_cytopl PF08337.7 EDO16397.1 - 0.23 9.7 2.6 2.8 6.1 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Metallophos PF00149.23 EDO16398.1 - 5e-13 48.8 2.8 5e-13 48.8 2.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Nipped-B_C PF12830.2 EDO16399.1 - 3.6e-47 160.4 8.8 5.6e-47 159.8 1.3 3.6 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EDO16399.1 - 2.1e-13 49.8 4.3 1.6e-12 47.0 2.3 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EDO16399.1 - 9.6e-05 22.1 0.3 0.82 9.9 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EDO16399.1 - 0.0004 20.5 0.0 2.4 8.4 0.0 4.2 4 0 0 4 4 4 2 HEAT repeats PseudoU_synth_2 PF00849.17 EDO16400.1 - 1e-17 64.4 0.0 1.1e-15 57.8 0.0 2.2 1 1 0 1 1 1 1 RNA pseudouridylate synthase PXA PF02194.10 EDO16401.1 - 2.6e-09 36.9 7.6 1.2e-07 31.4 2.2 3.3 2 1 1 3 3 3 3 PXA domain UQ_con PF00179.21 EDO16402.1 - 2.9e-43 146.6 0.1 4.5e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EDO16402.1 - 1.7e-25 88.3 0.6 2.8e-25 87.6 0.4 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EDO16402.1 - 0.00073 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B Calsarcin PF05556.6 EDO16402.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) DUF2874 PF11396.3 EDO16402.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) RWD PF05773.17 EDO16402.1 - 0.14 12.0 0.1 0.21 11.4 0.1 1.4 1 1 0 1 1 1 0 RWD domain Ada3 PF10198.4 EDO16403.1 - 2.1e-45 153.6 1.0 5.5e-45 152.3 0.7 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DinB PF05163.7 EDO16404.1 - 0.0036 17.0 1.5 0.0046 16.6 1.0 1.1 1 0 0 1 1 1 1 DinB family PTPA PF03095.10 EDO16404.1 - 0.19 10.8 1.4 0.23 10.6 1.0 1.1 1 0 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein AIF-MLS PF14962.1 EDO16404.1 - 0.2 11.2 11.5 0.32 10.6 8.0 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF3573 PF12097.3 EDO16404.1 - 0.34 9.4 5.0 0.41 9.1 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Polyoma_coat2 PF00761.15 EDO16404.1 - 0.68 9.3 2.6 0.77 9.1 1.2 1.5 1 1 1 2 2 2 0 Polyomavirus coat protein RP-C_C PF11800.3 EDO16404.1 - 0.92 9.1 8.8 1.4 8.5 6.1 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region DDHD PF02862.12 EDO16404.1 - 1.3 8.8 8.1 1.6 8.4 5.6 1.1 1 0 0 1 1 1 0 DDHD domain DUF2201_N PF13203.1 EDO16404.1 - 2.1 7.4 6.4 2.4 7.2 4.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain MRP-S28 PF10213.4 EDO16405.1 - 8e-49 164.9 4.2 1.4e-48 164.1 2.9 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein PfkB PF00294.19 EDO16406.1 - 3.2e-10 39.6 0.0 4.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TENA_THI-4 PF03070.11 EDO16407.1 - 1.9e-12 47.4 4.1 2.4e-12 47.0 2.9 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family LSM PF01423.17 EDO16408.1 - 1.6e-09 37.1 0.1 2.3e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain UQ_con PF00179.21 EDO16410.1 - 1.4e-38 131.4 0.1 2e-38 131.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDO16410.1 - 0.049 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 RWD domain DUF4502 PF14950.1 EDO16410.1 - 5.4 6.0 8.8 6.7 5.7 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) Epimerase PF01370.16 EDO16411.1 - 1.4e-19 70.5 0.1 1.8e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDO16411.1 - 1.6e-16 59.8 0.1 2e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EDO16411.1 - 1.9e-11 43.4 0.3 1.4e-10 40.5 0.2 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EDO16411.1 - 3e-11 43.6 0.1 5.1e-11 42.9 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EDO16411.1 - 7.5e-09 35.7 0.0 1.5e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO16411.1 - 7.3e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EDO16411.1 - 1.6e-05 24.3 0.0 0.00031 20.0 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EDO16411.1 - 4.8e-05 22.4 0.5 7.8e-05 21.7 0.3 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EDO16411.1 - 0.0036 16.2 0.1 0.0087 14.9 0.0 1.7 1 0 0 1 1 1 1 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EDO16411.1 - 0.0063 16.8 0.1 0.017 15.4 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain LRR_6 PF13516.1 EDO16412.1 - 7.1e-12 44.0 14.8 0.35 11.0 0.0 8.4 8 1 1 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.2 EDO16412.1 - 7.4e-10 38.2 21.6 0.0038 16.8 0.9 6.6 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDO16412.1 - 8.6e-09 34.2 9.4 2.6 8.4 0.1 7.8 7 1 1 8 8 8 4 Leucine Rich Repeat LRR_8 PF13855.1 EDO16412.1 - 7.4e-07 28.8 17.7 0.022 14.4 0.5 5.6 4 1 3 7 7 7 4 Leucine rich repeat LRR_7 PF13504.1 EDO16412.1 - 5.4e-06 25.7 5.8 0.92 9.9 0.1 6.1 6 0 0 6 6 6 1 Leucine rich repeat Acyltransferase PF01553.16 EDO16413.1 - 0.00065 19.1 0.3 0.002 17.5 0.2 1.9 1 1 1 2 2 2 1 Acyltransferase Gb3_synth PF04572.7 EDO16413.1 - 0.65 9.6 5.7 4.9 6.8 0.1 2.4 1 1 1 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region CybS PF05328.7 EDO16414.1 - 1.7e-48 163.6 0.0 2e-48 163.3 0.0 1.1 1 0 0 1 1 1 1 CybS C2 PF00168.25 EDO16415.1 - 4.9e-12 45.5 0.1 1.5e-11 43.9 0.1 1.9 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.4 EDO16415.1 - 1.3e-09 37.9 0.1 2.2e-08 33.9 0.0 2.9 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain SWIB PF02201.13 EDO16416.1 - 1.8e-22 78.7 0.1 2.9e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EDO16417.1 - 7.9e-10 38.3 0.1 1.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 DEK C terminal domain DUF4549 PF15082.1 EDO16417.1 - 0.0066 16.1 0.3 0.0086 15.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4549) Band_3_cyto PF07565.8 EDO16417.1 - 0.25 10.8 4.8 0.31 10.5 3.3 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Atg14 PF10186.4 EDO16417.1 - 4.1 6.2 11.6 4.8 6.0 8.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 EDO16417.1 - 5.5 5.8 6.2 6.8 5.5 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RhoGEF PF00621.15 EDO16418.1 - 1.8e-12 47.5 7.6 1.8e-12 47.5 5.3 2.5 2 1 0 2 2 2 1 RhoGEF domain BAR PF03114.13 EDO16418.1 - 0.084 12.3 3.9 0.03 13.8 0.7 1.7 2 0 0 2 2 2 0 BAR domain VPS11_C PF12451.3 EDO16419.1 - 1.8e-13 50.1 0.2 1.8e-13 50.1 0.1 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 EDO16419.1 - 0.017 14.9 7.3 0.038 13.8 5.0 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EDO16419.1 - 0.018 14.8 8.5 0.059 13.2 5.9 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EDO16419.1 - 0.055 13.2 2.3 0.12 12.1 1.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_12 PF13424.1 EDO16419.1 - 0.084 12.8 0.2 0.89 9.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-rbx1 PF12678.2 EDO16419.1 - 0.16 12.0 4.2 0.34 11.0 2.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EDO16419.1 - 0.42 10.6 8.7 1.1 9.3 6.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO16419.1 - 0.75 9.5 8.1 1.9 8.2 5.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO16419.1 - 2.8 7.6 9.3 7.5 6.2 6.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EDO16419.1 - 6.1 6.6 13.4 0.42 10.3 5.4 2.0 2 0 0 2 2 2 0 PHD-finger P5-ATPase PF12409.3 EDO16420.1 - 6.6e-37 126.0 1.9 1.5e-36 124.8 0.1 2.4 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 EDO16420.1 - 9.8e-31 106.5 0.1 2.6e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EDO16420.1 - 8.4e-22 78.2 0.0 1.8e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO16420.1 - 8.9e-15 55.6 0.0 5.8e-10 39.9 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO16420.1 - 2.7e-06 27.2 0.0 6.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EDO16420.1 - 0.00083 18.7 0.1 0.003 16.9 0.1 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDO16420.1 - 0.021 14.4 0.1 0.95 8.9 0.0 2.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SNARE_assoc PF09335.6 EDO16421.1 - 1.1e-14 54.6 8.7 1.1e-14 54.6 6.1 2.5 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF4234 PF14018.1 EDO16421.1 - 0.00084 19.0 10.9 21 4.9 7.6 3.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) Peptidase_M50 PF02163.17 EDO16421.1 - 0.067 12.1 0.1 0.23 10.3 0.0 2.1 1 1 0 1 1 1 0 Peptidase family M50 DUF3382 PF11862.3 EDO16421.1 - 0.39 10.6 4.4 0.26 11.2 1.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) DUF2207 PF09972.4 EDO16421.1 - 0.42 9.1 10.2 0.07 11.7 3.2 2.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF4341 PF14241.1 EDO16421.1 - 1.3 8.7 8.1 1.3 8.8 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4341) RseC_MucC PF04246.7 EDO16421.1 - 1.9 8.0 5.6 4.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC DUF3754 PF12576.3 EDO16421.1 - 2.1 7.9 5.5 0.23 11.0 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) NfeD PF01957.13 EDO16421.1 - 4.1 7.5 8.6 14 5.8 0.8 3.1 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF1049 PF06305.6 EDO16421.1 - 5.7 6.5 14.4 1.8 8.0 0.0 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) DUF4231 PF14015.1 EDO16421.1 - 8 6.4 8.6 1.2e+02 2.6 6.0 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Kin17_mid PF10357.4 EDO16422.1 - 6.6e-42 142.1 7.0 6.6e-42 142.1 4.9 2.2 2 1 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EDO16422.1 - 1.7e-06 28.0 5.4 1.7e-06 28.0 3.7 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO16422.1 - 1.3e-05 25.2 2.0 1.3e-05 25.2 1.4 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDO16422.1 - 0.0037 17.3 0.6 0.0037 17.3 0.4 3.4 3 1 1 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EDO16422.1 - 2.1 8.8 5.0 0.74 10.2 1.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger AKAP95 PF04988.7 EDO16422.1 - 2.2 8.0 19.6 0.024 14.4 2.1 2.8 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2 PF00096.21 EDO16422.1 - 6.5 7.3 8.2 0.59 10.5 1.9 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type RICTOR_N PF14664.1 EDO16423.1 - 1.2e-108 362.9 10.5 2.7e-108 361.8 7.3 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EDO16423.1 - 3e-72 242.2 5.1 3e-72 242.2 3.5 4.0 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EDO16423.1 - 4.3e-30 104.0 4.9 5.6e-30 103.6 0.9 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EDO16423.1 - 6.5e-27 93.2 3.3 1.8e-26 91.8 0.3 3.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.17 EDO16423.1 - 0.017 15.1 1.2 24 5.3 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat Arm PF00514.18 EDO16423.1 - 0.045 13.5 0.4 14 5.7 0.1 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF1961 PF09224.6 EDO16424.1 - 0.0032 16.5 0.0 0.0037 16.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) DUF2358 PF10184.4 EDO16424.1 - 0.042 13.7 2.0 0.057 13.3 1.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) PAD PF03068.10 EDO16424.1 - 0.055 11.8 0.1 0.062 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) Hom_end PF05204.9 EDO16424.1 - 0.12 12.3 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Homing endonuclease DUF4163 PF13739.1 EDO16424.1 - 0.5 11.1 4.5 0.74 10.6 3.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4163) HALZ PF02183.13 EDO16424.1 - 4.1 7.1 6.0 2 8.1 0.1 2.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper Dimer_Tnp_hAT PF05699.9 EDO16425.1 - 0.0072 15.9 0.1 0.059 12.9 0.0 2.6 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Meth_synt_2 PF01717.13 EDO16426.1 - 2.4e-137 457.2 0.0 4.4e-134 446.5 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EDO16426.1 - 1.1e-124 415.7 0.0 4.7e-112 374.2 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Pox_A6 PF04924.7 EDO16426.1 - 0.022 13.5 2.8 0.051 12.3 1.6 1.8 1 1 0 1 1 1 0 Poxvirus A6 protein SEP PF08059.8 EDO16427.1 - 5.9e-25 87.3 2.0 6.2e-25 87.3 0.2 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.15 EDO16427.1 - 5.6e-14 51.9 0.0 1e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EDO16427.1 - 6.9e-10 38.3 0.5 1.6e-09 37.1 0.4 1.6 1 0 0 1 1 1 1 UBA-like domain Chorismate_bind PF00425.13 EDO16428.1 - 1.7e-85 286.4 0.0 4.1e-85 285.1 0.0 1.6 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EDO16428.1 - 3.1e-30 105.0 0.2 3.4e-28 98.4 0.0 3.2 3 1 0 3 3 3 1 Anthranilate synthase component I, N terminal region POR PF01558.13 EDO16428.1 - 0.014 15.2 0.0 0.051 13.4 0.0 1.9 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase PP2C PF00481.16 EDO16429.1 - 1.3e-78 263.9 0.1 1.9e-78 263.3 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C MOZ_SAS PF01853.13 EDO16430.1 - 1e-76 256.4 1.4 2.1e-76 255.3 1.0 1.5 1 0 0 1 1 1 1 MOZ/SAS family RRM_6 PF14259.1 EDO16431.1 - 4.6e-10 39.3 0.0 1.1e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO16431.1 - 1.7e-08 33.9 0.1 4.3e-08 32.6 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO16431.1 - 0.00012 21.8 0.2 0.00067 19.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec61_beta PF03911.11 EDO16432.1 - 2.8e-18 65.4 0.5 3.4e-18 65.1 0.4 1.1 1 0 0 1 1 1 1 Sec61beta family tRNA-synt_2b PF00587.20 EDO16433.1 - 5.4e-33 114.0 0.1 9e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO16433.1 - 0.0034 17.2 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain zf-H2C2_2 PF13465.1 EDO16433.1 - 0.0067 16.6 2.4 0.016 15.4 1.7 1.6 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2HC_2 PF13913.1 EDO16433.1 - 0.05 13.2 0.7 0.13 12.0 0.5 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DUF948 PF06103.6 EDO16434.1 - 0.055 13.3 0.5 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Peroxin-13_N PF04088.8 EDO16435.1 - 4.2e-54 182.7 1.3 6.3e-54 182.2 0.9 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 EDO16435.1 - 1e-10 41.0 0.1 2.1e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDO16435.1 - 9.1e-10 37.7 0.1 1.8e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EDO16435.1 - 2.8e-08 33.1 0.0 6.1e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EDO16435.1 - 0.0002 21.4 0.3 0.0005 20.1 0.2 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain Abhydrolase_6 PF12697.2 EDO16436.1 - 5.6e-19 68.9 0.0 1e-18 68.0 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO16436.1 - 2.8e-14 53.2 0.0 4e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO16436.1 - 1.6e-08 34.4 0.0 3.1e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EDO16436.1 - 4.4e-06 26.4 0.0 7.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 EDO16436.1 - 0.0025 17.2 0.0 0.0045 16.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EDO16436.1 - 0.023 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 EDO16436.1 - 0.027 14.7 0.1 0.16 12.1 0.0 2.5 2 1 0 2 2 2 0 Thioesterase domain DUF2974 PF11187.3 EDO16436.1 - 0.039 13.3 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Flavokinase PF01687.12 EDO16437.1 - 2.8e-11 43.3 0.2 5.2e-11 42.5 0.0 1.4 2 0 0 2 2 2 1 Riboflavin kinase GLE1 PF07817.8 EDO16438.1 - 1e-90 303.1 0.1 1e-90 303.1 0.0 2.7 2 1 1 3 3 3 1 GLE1-like protein MAP7 PF05672.6 EDO16438.1 - 1.7e-06 27.5 50.9 1.3e-05 24.6 31.7 2.2 2 0 0 2 2 2 2 MAP7 (E-MAP-115) family U79_P34 PF03064.11 EDO16438.1 - 4.1 6.8 27.1 7.2 6.0 18.8 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Neur_chan_memb PF02932.11 EDO16438.1 - 7.1 6.4 13.0 13 5.6 9.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.3 EDO16438.1 - 7.8 5.7 20.6 13 4.9 14.3 1.3 1 0 0 1 1 1 0 SprA-related family V_ATPase_I PF01496.14 EDO16438.1 - 9.1 3.9 19.5 13 3.5 13.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L5_C PF00673.16 EDO16439.1 - 1.3e-21 76.1 0.0 6.4e-21 73.9 0.0 2.1 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EDO16439.1 - 5.2e-06 26.1 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_L7Ae PF01248.21 EDO16442.1 - 2e-26 91.2 0.2 3.3e-26 90.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family COMPASS-Shg1 PF05205.7 EDO16443.1 - 2.7e-25 88.7 5.9 3e-25 88.5 4.1 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 CEP170_C PF15308.1 EDO16443.1 - 0.019 13.2 0.1 0.021 13.1 0.1 1.0 1 0 0 1 1 1 0 CEP170 C-terminus PNPase PF03726.9 EDO16443.1 - 0.23 11.7 3.1 0.2 11.9 1.0 1.7 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain RhoGAP PF00620.22 EDO16445.1 - 6.6e-40 136.2 0.8 1.2e-38 132.0 0.0 2.6 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.18 EDO16445.1 - 7e-14 51.7 1.5 3.5e-13 49.5 1.0 2.2 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain P53_TAD PF08563.6 EDO16446.1 - 0.19 10.8 0.3 0.19 10.8 0.2 1.7 2 0 0 2 2 2 0 P53 transactivation motif Ras PF00071.17 EDO16447.1 - 2.9e-38 130.8 0.1 5.6e-38 129.8 0.1 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDO16447.1 - 8.4e-17 61.7 0.0 1.3e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO16447.1 - 7.9e-15 54.5 0.2 4.7e-14 52.0 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO16447.1 - 2.8e-07 30.1 0.0 5.9e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO16447.1 - 5.1e-07 29.6 0.1 8.8e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDO16447.1 - 1.3e-05 24.4 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EDO16447.1 - 0.0036 16.5 0.6 0.035 13.3 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EDO16447.1 - 0.067 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EDO16447.1 - 0.12 11.5 0.1 0.27 10.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 UBX PF00789.15 EDO16448.1 - 2.7e-16 59.4 0.1 6.5e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 UBX domain Snf7 PF03357.16 EDO16449.1 - 7.9e-11 41.6 18.7 8.5e-11 41.5 12.0 1.7 1 1 1 2 2 2 1 Snf7 Alpha-amyl_C PF09071.5 EDO16449.1 - 0.056 13.2 0.3 1.8 8.3 0.0 2.9 2 1 1 3 3 3 0 Alpha-amylase, C terminal Vps26 PF03643.10 EDO16450.1 - 3.7e-110 367.0 0.4 4.6e-110 366.7 0.3 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EDO16450.1 - 3.1e-05 23.8 0.1 0.00031 20.5 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EDO16450.1 - 0.00039 20.5 0.1 0.0027 17.8 0.0 2.3 1 1 1 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.5 EDO16450.1 - 0.1 11.6 4.0 0.28 10.2 0.8 2.1 1 1 0 2 2 2 0 Rgp1 Tim54 PF11711.3 EDO16451.1 - 1.3e-142 474.9 0.1 1.5e-142 474.7 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Lysine_decarbox PF03641.9 EDO16452.1 - 2.9e-43 146.8 0.0 3.8e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Methyltransf_16 PF10294.4 EDO16453.1 - 2.5e-22 79.1 1.1 3.3e-22 78.7 0.1 1.6 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 EDO16453.1 - 0.0033 17.0 0.1 0.012 15.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO16453.1 - 0.056 14.0 0.0 0.18 12.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EDO16453.1 - 0.11 11.8 0.2 1.1 8.5 0.2 2.2 1 1 0 1 1 1 0 Methyltransferase small domain Pkinase PF00069.20 EDO16454.1 - 7.4e-36 123.6 0.0 2.1e-35 122.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16454.1 - 3.2e-18 65.7 0.0 3.4e-17 62.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase HbrB PF08539.6 EDO16455.1 - 1.9e-36 125.3 1.9 3e-36 124.6 1.3 1.3 1 0 0 1 1 1 1 HbrB-like CLN3 PF02487.12 EDO16456.1 - 1.1e-133 445.9 24.1 2.9e-132 441.2 16.7 2.0 1 1 0 1 1 1 1 CLN3 protein DUF1674 PF07896.7 EDO16457.1 - 2.4e-17 62.8 1.4 4e-17 62.1 1.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) DSPc PF00782.15 EDO16458.1 - 1.1e-27 96.2 0.2 7.5e-22 77.3 0.1 3.7 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDO16458.1 - 1.9e-06 27.4 0.1 4.5e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EDO16458.1 - 0.00061 19.2 2.1 0.0011 18.4 0.2 2.4 3 0 0 3 3 3 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EDO16458.1 - 0.098 12.7 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Paf1 PF03985.8 EDO16459.1 - 2.2e-161 537.4 22.1 2.6e-161 537.2 15.3 1.0 1 0 0 1 1 1 1 Paf1 Esterase PF00756.15 EDO16460.1 - 8.8e-60 202.2 0.0 1e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EDO16460.1 - 0.0014 18.3 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EDO16460.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.2 EDO16460.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme WD40 PF00400.27 EDO16461.1 - 1.8e-15 56.1 0.0 5.3e-05 22.9 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EDO16461.1 - 0.0042 16.5 0.0 0.023 14.2 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-CCHC PF00098.18 EDO16462.1 - 9.7e-08 31.5 2.5 1.9e-07 30.6 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EDO16462.1 - 9.4e-05 22.4 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 EDO16462.1 - 0.01 15.5 1.6 0.022 14.5 1.1 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDO16462.1 - 0.023 14.3 0.9 0.048 13.3 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Peptidase_A2B PF12384.3 EDO16463.1 - 4.4e-21 74.9 0.0 6.6e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 EDO16463.1 - 0.00086 19.7 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 EDO16463.1 - 0.0083 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase (DUF1758) Asp_protease PF09668.5 EDO16463.1 - 0.054 13.0 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease RVP PF00077.15 EDO16463.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease rve PF00665.21 EDO16464.1 - 9.8e-15 54.7 0.0 1.4e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDO16464.1 - 0.0027 17.3 0.1 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EDO16464.1 - 0.093 12.2 0.0 0.37 10.3 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain UBN2 PF14223.1 EDO16465.1 - 0.00058 19.6 0.1 0.00098 18.9 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MAGE PF01454.14 EDO16465.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 MAGE family RVT_2 PF07727.9 EDO16466.1 - 4.8e-34 117.4 0.1 6.4e-34 117.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 EDO16467.1 - 8.1e-17 61.0 0.1 9.6e-17 60.7 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RRM_5 PF13893.1 EDO16468.1 - 1.3e-12 47.3 1.0 2.2e-06 27.4 0.1 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO16468.1 - 1.4e-09 37.3 0.6 1.4e-05 24.6 0.1 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO16468.1 - 6.9e-07 29.1 0.2 0.048 13.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EDO16468.1 - 0.0066 16.0 2.1 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 Calcipressin WG_beta_rep PF14903.1 EDO16468.1 - 0.097 12.9 0.1 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 WG containing repeat Limkain-b1 PF11608.3 EDO16468.1 - 0.29 10.8 2.8 12 5.7 0.0 2.9 3 0 0 3 3 3 0 Limkain b1 Adaptin_N PF01602.15 EDO16469.1 - 3.6e-116 388.5 15.5 4.3e-116 388.3 10.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EDO16469.1 - 1.6e-50 170.8 1.0 1.6e-50 170.8 0.7 2.5 3 0 0 3 3 3 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EDO16469.1 - 1e-08 35.2 0.6 0.016 15.4 0.1 4.4 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.17 EDO16469.1 - 0.013 15.5 2.7 9 6.6 0.0 5.3 7 0 0 7 7 7 0 HEAT repeat HEAT_EZ PF13513.1 EDO16469.1 - 0.11 13.0 0.1 0.63 10.6 0.1 2.4 2 0 0 2 2 2 0 HEAT-like repeat Rcd1 PF04078.8 EDO16470.1 - 3.6e-121 403.0 3.9 4.3e-121 402.7 2.7 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like AAA PF00004.24 EDO16471.1 - 4e-17 62.6 0.0 1.1e-16 61.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EDO16471.1 - 9.5e-17 61.1 4.6 2.1e-15 56.7 0.0 3.3 2 2 0 2 2 2 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EDO16471.1 - 5.8e-14 51.8 0.6 1.9e-13 50.2 0.4 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EDO16471.1 - 3.9e-10 39.0 0.2 4.1e-06 25.7 0.0 2.3 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EDO16471.1 - 3.7e-07 29.4 0.0 9.7e-07 28.0 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDO16471.1 - 3.8e-07 30.3 2.7 0.021 14.9 0.1 3.2 2 2 2 4 4 4 2 AAA domain AAA_14 PF13173.1 EDO16471.1 - 2.7e-06 27.3 0.1 1.5e-05 24.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EDO16471.1 - 3.5e-06 27.1 0.0 1.2e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_11 PF13086.1 EDO16471.1 - 1.2e-05 25.0 0.2 2.9e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EDO16471.1 - 2.3e-05 23.4 0.0 4.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EDO16471.1 - 7.9e-05 23.4 0.1 0.0016 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDO16471.1 - 9.7e-05 22.1 0.1 0.0018 18.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EDO16471.1 - 0.0001 21.9 0.0 0.00024 20.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EDO16471.1 - 0.00017 21.4 0.2 0.0071 16.1 0.0 2.5 2 1 1 3 3 2 1 Type III restriction enzyme, res subunit TIP49 PF06068.8 EDO16471.1 - 0.00022 20.0 0.0 0.0089 14.7 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 EDO16471.1 - 0.00027 20.4 0.0 0.00066 19.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DNA_pol3_delta PF06144.8 EDO16471.1 - 0.00041 19.9 1.5 0.00046 19.7 0.2 1.7 2 0 0 2 2 1 1 DNA polymerase III, delta subunit AAA_18 PF13238.1 EDO16471.1 - 0.00093 19.5 1.2 0.0093 16.2 0.0 2.5 1 1 1 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EDO16471.1 - 0.00097 18.8 0.1 0.0028 17.4 0.1 1.7 1 0 0 1 1 1 1 Archaeal ATPase DEAD PF00270.24 EDO16471.1 - 0.0011 18.5 0.2 0.0081 15.6 0.1 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_10 PF12846.2 EDO16471.1 - 0.0012 18.3 0.4 0.4 10.0 0.0 2.7 2 1 1 3 3 3 1 AAA-like domain AAA_25 PF13481.1 EDO16471.1 - 0.0017 17.7 0.1 0.084 12.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain UvrD-helicase PF00580.16 EDO16471.1 - 0.0027 17.0 0.6 0.098 11.9 0.3 2.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_24 PF13479.1 EDO16471.1 - 0.004 16.7 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDO16471.1 - 0.0056 16.2 1.0 0.2 11.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EDO16471.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EDO16471.1 - 0.012 14.5 0.1 0.052 12.5 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 EDO16471.1 - 0.013 15.3 0.0 0.035 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EDO16471.1 - 0.014 14.5 0.0 0.12 11.5 0.0 2.1 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EDO16471.1 - 0.015 15.4 0.0 0.036 14.2 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 EDO16471.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 EDO16471.1 - 0.024 14.5 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain GUCT PF08152.7 EDO16471.1 - 0.026 14.4 0.1 0.063 13.2 0.1 1.7 1 0 0 1 1 1 0 GUCT (NUC152) domain MobB PF03205.9 EDO16471.1 - 0.033 13.8 0.0 0.096 12.3 0.0 1.9 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 EDO16471.1 - 0.054 12.4 0.8 1.5 7.6 0.0 2.6 3 0 0 3 3 3 0 PIF1-like helicase SNF2_N PF00176.18 EDO16471.1 - 0.068 11.9 0.0 0.47 9.1 0.0 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_21 PF13304.1 EDO16471.1 - 0.086 12.7 0.8 4.5 7.1 0.6 2.3 1 1 0 1 1 1 0 AAA domain Methyltransf_31 PF13847.1 EDO16471.1 - 0.32 10.5 2.3 1.1 8.8 0.2 2.4 1 1 0 2 2 2 0 Methyltransferase domain AAA_23 PF13476.1 EDO16471.1 - 2 8.6 6.0 11 6.2 4.1 2.3 1 1 0 1 1 1 0 AAA domain Mid1 PF12929.2 EDO16472.1 - 1.3e-130 435.9 14.3 1.8e-130 435.5 9.9 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Erf4 PF10256.4 EDO16473.1 - 1.3e-32 112.1 0.0 1.8e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF1894 PF08979.6 EDO16473.1 - 0.056 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1894) ubiquitin PF00240.18 EDO16474.1 - 9.9e-08 31.2 0.1 1.9e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EDO16474.1 - 0.00018 21.3 0.5 0.00036 20.4 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like FmdA_AmdA PF03069.10 EDO16474.1 - 0.01 14.5 0.1 0.013 14.2 0.1 1.1 1 0 0 1 1 1 0 Acetamidase/Formamidase family Rad60-SLD PF11976.3 EDO16474.1 - 0.024 14.3 0.3 0.046 13.3 0.2 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2807 PF10988.3 EDO16474.1 - 0.047 13.2 1.0 0.071 12.6 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2807) RabGAP-TBC PF00566.13 EDO16475.1 - 1.7e-43 148.5 10.5 1.7e-43 148.5 7.3 3.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain PalH PF08733.5 EDO16476.1 - 5.7e-96 321.3 17.9 7.1e-96 321.0 12.4 1.1 1 0 0 1 1 1 1 PalH/RIM21 Pet20 PF08692.5 EDO16477.1 - 1e-11 44.8 0.1 5.4e-11 42.5 0.0 2.3 1 1 1 2 2 2 1 Mitochondrial protein Pet20 RNA_pol_Rpb1_5 PF04998.12 EDO16477.1 - 0.81 8.8 5.9 0.14 11.3 1.3 1.8 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 DUF2536 PF10750.4 EDO16477.1 - 2.2 7.9 7.8 1.3 8.6 0.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2536) Pkinase PF00069.20 EDO16478.1 - 6.1e-66 222.2 0.1 1.1e-65 221.3 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16478.1 - 1.6e-50 171.5 0.1 3e-50 170.7 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EDO16478.1 - 2.3e-21 75.9 0.3 2.3e-21 75.9 0.2 3.1 3 0 0 3 3 3 1 P21-Rho-binding domain PH PF00169.24 EDO16478.1 - 6.3e-08 32.7 1.5 2.2e-07 31.0 1.1 2.0 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EDO16478.1 - 1.1e-05 24.5 0.0 1.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO16478.1 - 0.051 13.3 0.1 0.14 11.8 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EDO16479.1 - 2.1e-72 243.3 1.4 1.2e-71 240.8 1.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16479.1 - 2.8e-40 138.0 0.4 3.7e-38 131.0 0.0 2.5 1 1 1 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 EDO16479.1 - 2.6e-20 71.5 0.0 5.2e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EDO16479.1 - 6.3e-08 31.9 0.2 1.5e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDO16479.1 - 2.3e-05 23.5 0.1 6.6e-05 22.0 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO16479.1 - 0.0075 16.0 0.0 0.03 14.0 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family ketoacyl-synt PF00109.21 EDO16481.1 - 9.2e-52 176.0 0.0 1.2e-51 175.6 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EDO16481.1 - 4.1e-28 97.6 0.2 7.6e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EDO16481.1 - 0.0004 19.4 0.1 0.00098 18.1 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EDO16481.1 - 0.28 10.8 2.0 3 7.5 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SAP PF02037.22 EDO16482.1 - 6.7e-13 47.7 0.5 1.6e-12 46.6 0.4 1.7 1 0 0 1 1 1 1 SAP domain Vhr1 PF04001.8 EDO16484.1 - 4.9e-49 164.1 4.2 1.1e-48 163.0 2.9 1.6 1 0 0 1 1 1 1 Transcription factor Vhr1 Glyco_transf_15 PF01793.11 EDO16485.1 - 4e-106 354.7 12.0 4e-106 354.7 8.3 1.4 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase TPR_11 PF13414.1 EDO16486.1 - 3.9e-15 55.2 5.8 2.4e-12 46.3 2.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EDO16486.1 - 2.2e-11 42.8 10.5 9.8e-06 24.9 0.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDO16486.1 - 5.8e-09 35.2 4.8 0.008 16.0 0.2 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO16486.1 - 9.1e-05 22.5 3.9 0.00018 21.5 2.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EDO16486.1 - 0.00056 20.5 0.1 0.028 15.1 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO16486.1 - 0.00092 19.1 1.6 0.16 11.9 0.2 2.8 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDO16486.1 - 0.0021 18.0 1.3 0.035 14.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDO16486.1 - 0.052 13.9 0.1 4.2 7.7 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDO16486.1 - 0.061 13.9 0.0 7.7 7.4 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDO16486.1 - 0.37 10.7 4.1 14 5.6 0.1 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 EDO16486.1 - 1.6 8.6 4.3 8.4 6.4 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat INCENP_ARK-bind PF03941.10 EDO16487.1 - 1.2e-20 73.0 3.1 3.2e-20 71.6 2.2 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region LRR_4 PF12799.2 EDO16489.1 - 1.9e-06 27.3 7.5 0.02 14.5 0.0 5.9 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO16489.1 - 9.2e-06 25.3 8.5 0.025 14.3 0.5 4.6 4 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.1 EDO16489.1 - 0.00011 21.9 15.5 0.1 12.6 0.0 6.2 5 1 1 6 6 6 3 Leucine Rich repeat F-box-like PF12937.2 EDO16489.1 - 0.013 15.2 0.3 0.04 13.6 0.0 2.1 2 1 0 2 2 2 0 F-box-like Recep_L_domain PF01030.19 EDO16489.1 - 0.028 14.3 0.1 0.028 14.3 0.1 3.1 3 1 0 3 3 3 0 Receptor L domain adh_short PF00106.20 EDO16490.1 - 1.3e-21 77.2 0.0 1.7e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO16490.1 - 9e-11 41.9 0.2 1.3e-10 41.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO16490.1 - 6.9e-08 32.3 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDO16490.1 - 0.023 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EDO16490.1 - 0.026 13.4 0.4 0.053 12.4 0.3 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein T_Ag_DNA_bind PF02217.11 EDO16490.1 - 0.081 13.3 0.2 0.33 11.3 0.0 2.2 2 0 0 2 2 2 0 Origin of replication binding protein Pkinase PF00069.20 EDO16491.1 - 3.1e-73 246.1 0.0 3.5e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16491.1 - 1.2e-32 112.9 0.0 1.5e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO16491.1 - 5.5e-06 25.5 0.0 1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO16491.1 - 0.003 17.3 0.1 0.06 13.0 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EDO16491.1 - 0.022 13.8 0.1 0.071 12.1 0.0 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2401 PF10287.4 EDO16492.1 - 5.5e-101 336.9 2.4 5.5e-101 336.9 1.7 2.0 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EDO16492.1 - 3e-30 104.1 1.5 6.5e-30 103.0 0.2 2.3 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Menin PF05053.8 EDO16492.1 - 0.0052 15.0 10.4 0.0067 14.6 7.2 1.1 1 0 0 1 1 1 1 Menin Macoilin PF09726.4 EDO16492.1 - 1.1 7.4 14.3 1.4 7.0 9.9 1.1 1 0 0 1 1 1 0 Transmembrane protein ABC2_membrane PF01061.19 EDO16493.1 - 3.5e-72 241.9 52.4 1.8e-39 135.1 9.8 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EDO16493.1 - 1e-36 126.2 0.0 7.9e-18 65.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EDO16493.1 - 8.7e-33 112.0 3.0 1.8e-27 95.0 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EDO16493.1 - 1.8e-10 40.7 0.1 3.9e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EDO16493.1 - 1.1e-06 27.8 0.0 0.0002 20.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EDO16493.1 - 3.4e-05 23.3 0.1 0.0013 18.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EDO16493.1 - 7.1e-05 22.2 0.3 0.031 13.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EDO16493.1 - 0.0001 21.7 0.2 0.015 14.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EDO16493.1 - 0.00014 21.8 0.3 0.0056 16.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EDO16493.1 - 0.00015 21.1 0.0 1.5 8.0 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EDO16493.1 - 0.00028 21.7 0.0 0.0098 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDO16493.1 - 0.00039 20.5 0.2 0.032 14.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EDO16493.1 - 0.00053 19.1 10.9 0.00053 19.1 7.5 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein MMR_HSR1 PF01926.18 EDO16493.1 - 0.0032 17.4 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase UPF0079 PF02367.12 EDO16493.1 - 0.0038 16.8 0.9 0.019 14.5 0.2 2.2 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EDO16493.1 - 0.0052 16.4 0.0 0.084 12.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EDO16493.1 - 0.0052 16.4 0.3 0.19 11.4 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EDO16493.1 - 0.0057 15.7 0.0 1.3 8.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 EDO16493.1 - 0.0062 16.8 0.0 0.14 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EDO16493.1 - 0.0065 16.4 0.2 0.13 12.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 EDO16493.1 - 0.013 15.1 0.1 13 5.4 0.0 3.3 3 0 0 3 3 3 0 NTPase SbcCD_C PF13558.1 EDO16493.1 - 0.017 15.0 0.1 3.2 7.7 0.0 3.5 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EDO16493.1 - 0.03 13.7 0.6 4 6.7 0.2 2.9 3 0 0 3 3 3 0 AAA-like domain AAA_33 PF13671.1 EDO16493.1 - 0.069 13.0 0.2 1.2 9.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 EDO16493.1 - 0.077 13.5 0.1 18 5.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 EDO16493.1 - 0.1 12.0 0.9 1.2 8.5 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EDO16493.1 - 0.11 12.0 0.3 2.4 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EDO16493.1 - 0.15 12.2 0.0 2.6 8.2 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Exo5 PF09810.4 EDO16494.1 - 1.3e-23 83.7 0.1 3.7e-22 78.9 0.1 2.5 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EDO16494.1 - 0.019 14.3 0.1 0.08 12.3 0.0 2.2 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 EDO16494.1 - 0.11 12.3 2.6 4.1 7.2 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF83 Glutaredoxin PF00462.19 EDO16495.1 - 6.9e-18 64.3 0.0 9.9e-18 63.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin DDDD PF10161.4 EDO16495.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Raptor_N PF14538.1 EDO16496.1 - 6.5e-64 214.4 9.8 3.9e-63 211.9 0.0 3.0 3 0 0 3 3 3 2 Raptor N-terminal CASPase like domain HEAT PF02985.17 EDO16496.1 - 3.5e-06 26.6 0.6 0.023 14.7 0.0 4.9 5 0 0 5 5 5 1 HEAT repeat WD40 PF00400.27 EDO16496.1 - 1.2e-05 25.0 6.6 0.5 10.3 0.0 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat HEAT_2 PF13646.1 EDO16496.1 - 0.00011 22.3 0.0 0.016 15.4 0.0 3.2 3 0 0 3 3 3 1 HEAT repeats DUF2435 PF10363.4 EDO16496.1 - 0.0014 18.4 1.0 0.0047 16.7 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Elong_Iki1 PF10483.4 EDO16497.1 - 6.4e-95 317.7 4.2 7.2e-95 317.5 2.9 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 DUF1869 PF08956.5 EDO16497.1 - 0.097 12.2 0.6 2.1 8.0 0.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1869) Gpi16 PF04113.9 EDO16498.1 - 8.3e-36 123.1 0.5 1.1e-35 122.6 0.3 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF1793 PF08760.6 EDO16498.1 - 0.031 14.1 0.6 0.072 12.9 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) DEAD PF00270.24 EDO16499.1 - 9.1e-46 155.4 0.6 4e-45 153.3 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO16499.1 - 2.9e-22 78.2 0.0 6.2e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EDO16499.1 - 4.7e-21 74.0 0.2 1.1e-20 72.9 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) SecA_DEAD PF07517.9 EDO16499.1 - 0.0056 16.0 0.0 0.017 14.4 0.0 1.6 1 1 0 1 1 1 1 SecA DEAD-like domain ResIII PF04851.10 EDO16499.1 - 0.0071 16.1 0.0 0.022 14.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EDO16499.1 - 0.074 13.1 1.0 0.39 10.8 0.7 2.3 2 1 0 2 2 2 0 AAA domain PhoD PF09423.5 EDO16500.1 - 0.00063 18.4 1.2 0.22 10.0 0.0 2.7 2 1 0 2 2 2 2 PhoD-like phosphatase Pkinase PF00069.20 EDO16501.1 - 1.7e-52 178.1 0.5 4.9e-51 173.3 0.1 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16501.1 - 7.6e-25 87.4 0.0 4.2e-22 78.4 0.0 3.1 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO16501.1 - 0.044 12.7 0.2 6.4 5.6 0.1 2.2 2 0 0 2 2 2 0 Kinase-like DnaJ_CXXCXGXG PF00684.14 EDO16502.1 - 0.00028 20.8 6.8 0.16 12.0 0.5 2.5 2 1 0 2 2 2 2 DnaJ central domain HypA PF01155.14 EDO16502.1 - 0.078 12.6 2.6 1.8 8.2 0.5 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EDO16502.1 - 0.27 11.0 4.7 1.6 8.6 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon TMEM51 PF15345.1 EDO16502.1 - 3.9 7.1 6.2 0.8 9.3 2.0 1.5 2 0 0 2 2 2 0 Transmembrane protein 51 zf-RING_5 PF14634.1 EDO16502.1 - 3.9 7.2 6.9 36 4.2 1.8 2.8 2 1 1 3 3 3 0 zinc-RING finger domain AAA PF00004.24 EDO16503.1 - 5.4e-49 165.7 2.5 1.3e-42 145.1 0.0 3.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EDO16503.1 - 2.5e-06 27.5 0.0 5.1e-05 23.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.20 EDO16503.1 - 1.2e-05 25.1 0.0 5.7e-05 22.9 0.0 2.2 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.9 EDO16503.1 - 3.2e-05 23.6 0.0 9.9e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO16503.1 - 5.4e-05 23.2 0.2 0.00049 20.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EDO16503.1 - 5.7e-05 23.1 0.3 0.17 11.8 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EDO16503.1 - 9.7e-05 21.8 0.0 0.00024 20.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 EDO16503.1 - 0.00028 21.0 0.5 0.0089 16.1 0.1 3.2 2 1 0 2 2 2 1 AAA domain ResIII PF04851.10 EDO16503.1 - 0.002 17.9 0.1 0.015 15.0 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EDO16503.1 - 0.0021 17.4 0.0 0.007 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EDO16503.1 - 0.0061 15.3 0.0 0.022 13.4 0.0 1.9 3 0 0 3 3 3 1 TIP49 C-terminus Sigma54_activat PF00158.21 EDO16503.1 - 0.0069 15.8 0.0 1.1 8.6 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 EDO16503.1 - 0.008 15.9 0.0 0.022 14.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EDO16503.1 - 0.011 15.6 0.0 0.036 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDO16503.1 - 0.02 15.0 0.2 0.11 12.6 0.0 2.4 3 0 0 3 3 1 0 RNA helicase AAA_17 PF13207.1 EDO16503.1 - 0.026 15.3 0.0 0.026 15.3 0.0 3.8 3 2 1 4 4 2 0 AAA domain Mg_chelatase PF01078.16 EDO16503.1 - 0.038 13.1 0.1 0.13 11.3 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EDO16503.1 - 0.047 12.7 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 EDO16503.1 - 0.062 13.5 2.4 0.22 11.8 0.0 3.0 3 0 0 3 3 3 0 ABC transporter AAA_3 PF07726.6 EDO16503.1 - 0.065 12.8 0.0 0.19 11.3 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EDO16503.1 - 0.19 11.9 0.0 0.19 11.9 0.0 3.6 3 0 0 3 3 3 0 AAA domain DUF2361 PF10153.4 EDO16504.1 - 1.9e-37 127.9 16.1 1.9e-37 127.9 11.2 2.1 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) VanY PF02557.12 EDO16504.1 - 0.015 15.0 0.3 0.95 9.3 0.1 2.3 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase DUF1257 PF06868.6 EDO16504.1 - 0.094 12.6 1.8 0.13 12.1 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1257) DUF3591 PF12157.3 EDO16505.1 - 2.7e-195 649.1 0.7 6e-195 647.9 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EDO16505.1 - 1.1e-05 24.9 0.9 2.5e-05 23.8 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle CitF PF04223.7 EDO16505.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) Cuticle_2 PF08184.6 EDO16505.1 - 0.2 11.4 0.0 0.49 10.2 0.0 1.6 1 0 0 1 1 1 0 Cuticle protein 7 isoform family zf-CCHC PF00098.18 EDO16505.1 - 0.23 11.4 0.3 0.56 10.2 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle RNase_T PF00929.19 EDO16506.1 - 9.8e-27 94.2 0.1 2.2e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 Exonuclease ETRAMP PF09716.5 EDO16506.1 - 0.072 13.0 0.6 0.84 9.6 0.2 2.6 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) ABC_tran PF00005.22 EDO16507.1 - 4.9e-35 120.8 0.0 1.1e-34 119.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EDO16507.1 - 7e-32 110.9 16.1 8.8e-32 110.5 11.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EDO16507.1 - 6.3e-09 36.2 2.2 0.00081 19.4 0.0 3.6 2 2 1 3 3 3 2 AAA domain SMC_N PF02463.14 EDO16507.1 - 2.1e-07 30.4 0.3 0.00045 19.5 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDO16507.1 - 0.00014 21.3 0.4 0.0016 17.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EDO16507.1 - 0.00017 21.6 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.4 EDO16507.1 - 0.0013 17.4 0.0 0.044 12.3 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.1 EDO16507.1 - 0.0031 17.6 0.0 0.02 15.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO16507.1 - 0.0045 17.7 0.8 0.014 16.2 0.5 2.1 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EDO16507.1 - 0.0079 15.3 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.24 EDO16507.1 - 0.0093 16.1 0.0 0.084 13.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EDO16507.1 - 0.011 15.2 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain SbcCD_C PF13558.1 EDO16507.1 - 0.03 14.2 0.3 0.16 11.8 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EDO16507.1 - 0.03 14.6 8.3 0.26 11.5 0.3 2.9 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EDO16507.1 - 0.048 13.0 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO16507.1 - 0.068 13.4 0.4 0.27 11.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EDO16507.1 - 0.081 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RNA12 PF10443.4 EDO16508.1 - 4.9e-167 555.8 2.8 4.9e-167 555.8 1.9 1.8 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 EDO16508.1 - 1.4e-05 24.6 0.0 3.7e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 EDO16508.1 - 3e-05 23.8 1.3 0.00051 19.8 0.0 3.1 1 1 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 EDO16508.1 - 0.0018 18.1 0.0 0.01 15.7 0.0 2.4 1 0 0 1 1 1 1 AAA domain RRM_5 PF13893.1 EDO16508.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_22 PF13401.1 EDO16508.1 - 0.097 12.8 1.0 2 8.5 0.0 3.0 1 1 1 2 2 2 0 AAA domain USP7_C2 PF14533.1 EDO16509.1 - 2.2e-55 187.3 7.8 3.7e-53 180.1 3.6 2.9 2 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EDO16509.1 - 1.3e-51 175.3 2.2 2.4e-51 174.4 1.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EDO16509.1 - 2.2e-33 115.5 4.5 5e-33 114.3 0.3 3.0 2 1 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 EDO16509.1 - 2.3e-30 106.0 0.0 4.3e-30 105.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UN_NPL4 PF11543.3 EDO16509.1 - 0.0011 19.2 1.4 0.5 10.6 0.1 4.5 5 0 0 5 5 5 1 Nuclear pore localisation protein NPL4 Glyco_hydro_17 PF00332.13 EDO16510.1 - 3.8e-09 36.0 0.8 3.8e-09 36.0 0.6 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 Mucin PF01456.12 EDO16510.1 - 1.3 8.7 19.1 3 7.6 13.2 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein MSP1_C PF07462.6 EDO16510.1 - 1.8 6.8 4.1 2.4 6.4 2.9 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus HEAT PF02985.17 EDO16511.1 - 2.1e-22 77.1 11.1 0.00068 19.5 0.0 11.5 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.1 EDO16511.1 - 7.1e-21 74.2 4.5 1.1e-08 35.2 0.0 6.3 5 1 2 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 EDO16511.1 - 5.6e-20 71.2 15.5 1.2e-07 31.9 0.0 11.0 10 2 3 13 13 13 3 HEAT-like repeat MMS19_C PF12460.3 EDO16511.1 - 5.1e-07 28.7 14.9 0.0027 16.4 3.5 5.0 5 2 1 6 6 6 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 EDO16511.1 - 4.4e-06 27.0 0.0 0.16 12.3 0.0 5.6 4 1 3 7 7 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EDO16511.1 - 8.2e-06 25.3 0.7 0.0052 16.1 0.2 4.6 4 1 0 4 4 4 1 CLASP N terminal Arm PF00514.18 EDO16511.1 - 6.8e-05 22.5 12.3 0.49 10.2 0.0 6.8 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.6 EDO16511.1 - 0.0032 17.0 0.0 0.048 13.1 0.0 2.9 3 0 0 3 3 3 1 DNA alkylation repair enzyme V-ATPase_H_N PF03224.9 EDO16511.1 - 0.0035 16.4 5.5 0.057 12.5 0.6 3.1 3 0 0 3 3 3 2 V-ATPase subunit H eIF-3c_N PF05470.7 EDO16512.1 - 1.8e-156 521.6 19.5 1.3e-122 409.9 3.4 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EDO16512.1 - 1.6e-10 41.1 3.2 3.6e-10 40.0 0.2 3.1 2 2 0 2 2 2 1 PCI domain IPP-2 PF04979.9 EDO16513.1 - 2.1e-08 34.4 14.8 2.1e-08 34.4 10.2 2.0 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Latarcin PF10279.4 EDO16513.1 - 0.081 13.1 4.6 0.19 11.9 2.1 2.7 1 1 0 1 1 1 0 Latarcin precursor PG_binding_4 PF12229.3 EDO16513.1 - 0.14 12.3 3.4 0.44 10.7 0.3 2.3 2 1 0 2 2 2 0 Putative peptidoglycan binding domain PEHE PF15275.1 EDO16513.1 - 1.8 9.0 14.4 0.067 13.6 5.2 2.1 2 1 0 2 2 2 0 PEHE domain SURF4 PF02077.10 EDO16514.1 - 9.5e-103 343.2 14.1 1.1e-102 343.0 9.8 1.0 1 0 0 1 1 1 1 SURF4 family HR_lesion PF05514.6 EDO16514.1 - 8.6 6.1 13.5 0.062 13.1 2.6 2.4 2 2 1 3 3 3 0 HR-like lesion-inducing Thioredoxin PF00085.15 EDO16515.1 - 0.001 18.7 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF3336 PF11815.3 EDO16516.1 - 5.5e-30 103.7 0.1 1e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EDO16516.1 - 2.1e-08 34.3 0.0 3.7e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase MFS_1 PF07690.11 EDO16517.1 - 3.8e-09 35.7 38.3 1.7e-08 33.5 22.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO16517.1 - 3.5e-06 25.8 6.7 3.5e-06 25.8 4.7 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter adh_short PF00106.20 EDO16518.1 - 1.2e-17 64.3 0.0 1.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO16518.1 - 7.7e-11 41.9 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDO16518.1 - 2.7e-05 24.0 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EDO16518.1 - 0.00082 19.4 0.0 0.01 15.8 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding DUF4257 PF14074.1 EDO16520.1 - 0.0015 18.1 0.7 0.0026 17.3 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4257) Ribonuclease_3 PF00636.21 EDO16521.1 - 3.1e-09 37.2 0.4 1.7e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.20 EDO16521.1 - 2e-07 31.4 0.0 4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif FA_desaturase PF00487.19 EDO16521.1 - 0.1 12.0 0.3 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Pex2_Pex12 PF04757.9 EDO16523.1 - 2.9e-43 147.9 13.3 3.5e-43 147.6 9.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EDO16523.1 - 9.5e-07 28.7 5.4 1.6e-06 28.0 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO16523.1 - 1.7e-05 24.4 2.5 2.6e-05 23.8 1.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO16523.1 - 0.0017 18.1 6.9 0.003 17.4 4.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EDO16523.1 - 0.0048 16.6 4.3 0.0084 15.9 3.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EDO16523.1 - 0.035 13.7 4.3 0.06 13.0 3.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) F_bP_aldolase PF01116.15 EDO16524.1 - 8.9e-95 317.0 0.0 1e-94 316.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF89 PF01937.14 EDO16525.1 - 2.9e-109 365.1 5.5 3.3e-109 364.9 3.8 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DWNN PF08783.6 EDO16526.1 - 5.1e-34 116.0 1.6 2.4e-32 110.7 0.1 2.5 2 0 0 2 2 2 1 DWNN domain U-box PF04564.10 EDO16526.1 - 1.3e-07 31.5 0.0 4.2e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 EDO16526.1 - 1.4e-06 27.6 0.6 3.8e-06 26.3 0.4 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CCHC PF00098.18 EDO16526.1 - 0.0035 17.2 3.0 0.0069 16.2 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EDO16526.1 - 0.0056 16.1 3.6 0.011 15.1 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EDO16526.1 - 0.071 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle Rubredoxin PF00301.15 EDO16526.1 - 0.097 12.5 3.6 7.8 6.4 0.0 3.1 3 0 0 3 3 3 0 Rubredoxin zf-RING_6 PF14835.1 EDO16526.1 - 0.12 12.1 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TFIIA_gamma_C PF02751.9 EDO16527.1 - 2.8e-26 91.0 0.6 4e-26 90.5 0.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EDO16527.1 - 1.2e-24 85.6 0.1 1.8e-24 85.0 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TAP42 PF04177.7 EDO16528.1 - 6.5e-95 317.9 20.7 7.3e-95 317.7 14.4 1.0 1 0 0 1 1 1 1 TAP42-like family Imm36 PF15597.1 EDO16528.1 - 0.29 11.3 4.6 0.077 13.1 0.7 2.0 2 0 0 2 2 2 0 Immunity protein 36 TCTP PF00838.12 EDO16529.1 - 4.6e-72 241.3 0.5 5.3e-72 241.1 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein adh_short PF00106.20 EDO16530.1 - 9.7e-13 48.3 0.0 1.5e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EDO16530.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NYD-SP28_assoc PF14775.1 EDO16530.1 - 0.012 15.2 0.1 0.25 11.0 0.0 2.8 3 0 0 3 3 3 0 Sperm tail C-terminal domain KR PF08659.5 EDO16530.1 - 0.13 11.9 0.0 4.4 6.9 0.0 2.4 2 1 0 2 2 2 0 KR domain UPF0203 PF05254.7 EDO16531.1 - 2e-30 104.4 4.2 2.3e-30 104.2 2.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 EDO16531.1 - 0.0036 17.2 2.6 0.72 9.8 0.2 2.1 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein Cmc1 PF08583.5 EDO16531.1 - 0.0041 16.8 3.6 0.086 12.6 0.3 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EDO16531.1 - 0.32 11.0 3.0 14 5.8 2.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EDO16531.1 - 1.2 9.2 7.9 2.8 8.0 1.1 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DASH_Ask1 PF08655.5 EDO16532.1 - 1.2e-30 105.0 0.5 2.5e-30 104.0 0.3 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 Frag1 PF10277.4 EDO16533.1 - 4.2e-81 271.5 24.9 5e-81 271.2 17.3 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3593 PF12159.3 EDO16533.1 - 0.059 13.1 2.1 0.26 11.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3593) DUF872 PF05915.7 EDO16533.1 - 0.21 11.4 2.1 0.72 9.7 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3671 PF12420.3 EDO16533.1 - 4.8 7.2 8.4 7.3 6.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function FCH PF00611.18 EDO16534.1 - 3e-17 62.5 0.0 3e-17 62.5 0.0 3.1 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 EDO16534.1 - 0.00019 20.8 0.0 0.00041 19.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EDO16534.1 - 0.0019 17.7 0.0 0.0042 16.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDO16534.1 - 0.0048 16.2 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain EcoEI_R_C PF08463.5 EDO16534.1 - 0.46 10.3 10.6 0.032 14.0 2.0 2.8 3 1 0 3 3 3 0 EcoEI R protein C-terminal Cyt-b5 PF00173.23 EDO16535.1 - 5.4e-13 48.5 0.0 7.1e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TFR_dimer PF04253.10 EDO16536.1 - 7.6e-35 119.2 0.9 1.3e-34 118.4 0.2 1.7 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EDO16536.1 - 0.00041 20.1 0.0 0.00082 19.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PIGA PF08288.7 EDO16537.1 - 3.8e-43 145.7 0.2 1.2e-42 144.1 0.1 1.9 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EDO16537.1 - 2e-28 98.9 0.0 3.5e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EDO16537.1 - 1.2e-20 73.9 0.1 2.6e-20 72.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EDO16537.1 - 2.6e-16 60.1 0.0 4.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EDO16537.1 - 1.5e-13 51.0 0.1 2.7e-12 46.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 EDO16537.1 - 5.1e-06 26.3 0.3 1.6e-05 24.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EDO16537.1 - 0.0022 18.1 0.0 0.0056 16.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 EF-hand_1 PF00036.27 EDO16538.1 - 1.5e-26 89.6 14.3 9.1e-08 30.8 1.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EDO16538.1 - 5.2e-25 87.3 12.1 4.2e-14 52.4 1.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDO16538.1 - 6.8e-22 75.3 12.4 1.2e-06 27.9 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EDO16538.1 - 1.9e-18 65.8 12.0 9.1e-12 44.4 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EDO16538.1 - 7.7e-17 59.7 11.4 1.4e-05 24.2 0.1 4.1 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EDO16538.1 - 4.5e-07 29.6 0.5 0.027 14.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EDO16538.1 - 2.3e-06 27.3 2.9 0.0015 18.2 0.0 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EDO16538.1 - 0.0036 17.3 0.2 0.36 10.8 0.0 2.2 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region GAD PF02938.9 EDO16538.1 - 0.0052 16.9 0.1 0.59 10.3 0.0 2.3 2 0 0 2 2 2 1 GAD domain VCBS PF13517.1 EDO16538.1 - 0.024 14.9 3.5 0.24 11.7 0.0 2.6 3 1 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella MerR-DNA-bind PF09278.6 EDO16538.1 - 0.11 12.8 2.1 11 6.5 0.1 2.9 3 1 0 3 3 3 0 MerR, DNA binding Caleosin PF05042.8 EDO16538.1 - 0.15 11.5 0.2 0.86 9.1 0.2 2.3 1 1 0 1 1 1 0 Caleosin related protein MgtE_N PF03448.12 EDO16538.1 - 0.16 12.3 1.5 0.44 10.8 0.1 2.2 3 0 0 3 3 3 0 MgtE intracellular N domain HIT PF01230.18 EDO16540.1 - 1e-18 67.6 0.6 8.3e-18 64.7 0.3 2.0 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EDO16540.1 - 1.8e-14 53.9 8.5 5.8e-14 52.3 5.9 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2H2_4 PF13894.1 EDO16540.1 - 0.00065 19.8 0.7 0.0031 17.7 0.5 2.3 1 1 0 1 1 1 1 C2H2-type zinc finger zf-BED PF02892.10 EDO16540.1 - 0.016 14.9 0.1 0.035 13.8 0.1 1.5 1 0 0 1 1 1 0 BED zinc finger zf-C2H2 PF00096.21 EDO16540.1 - 1.2 9.5 8.7 0.22 11.9 0.5 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EDO16540.1 - 1.8 8.7 7.7 0.62 10.1 2.6 2.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) AAA PF00004.24 EDO16541.1 - 1.1e-42 145.3 0.0 2e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO16541.1 - 1.3e-06 28.1 1.1 4e-05 23.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO16541.1 - 1.4e-06 28.4 0.0 6.4e-05 23.0 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EDO16541.1 - 1.8e-05 24.7 0.0 7.2e-05 22.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EDO16541.1 - 8e-05 21.8 0.0 0.00017 20.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDO16541.1 - 8.7e-05 22.6 0.1 0.0056 16.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO16541.1 - 0.00016 21.3 0.1 0.00034 20.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDO16541.1 - 0.00047 20.9 1.2 0.0016 19.2 0.1 2.4 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EDO16541.1 - 0.0012 18.5 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 TIP49 PF06068.8 EDO16541.1 - 0.0018 17.0 0.1 0.0037 16.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EDO16541.1 - 0.0019 18.3 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 EDO16541.1 - 0.0032 16.8 0.7 0.031 13.6 0.3 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO16541.1 - 0.0035 17.6 0.2 0.048 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EDO16541.1 - 0.0036 16.7 0.1 0.0075 15.6 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EDO16541.1 - 0.0054 15.9 0.2 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EDO16541.1 - 0.0074 16.1 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EDO16541.1 - 0.0086 16.0 0.3 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EDO16541.1 - 0.0091 15.5 0.3 0.021 14.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO16541.1 - 0.013 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EDO16541.1 - 0.044 12.8 0.7 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.11 EDO16541.1 - 0.05 12.8 1.5 0.07 12.3 0.1 1.8 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EDO16541.1 - 0.065 12.3 2.2 0.088 11.9 0.0 2.3 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.12 EDO16541.1 - 0.066 12.0 0.1 0.13 11.0 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EDO16541.1 - 0.073 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDO16541.1 - 0.097 12.3 0.1 0.26 10.9 0.1 1.9 1 1 0 1 1 1 0 NACHT domain Phage_GP20 PF06810.6 EDO16541.1 - 0.14 11.5 5.8 3.1 7.2 3.1 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 AAA_11 PF13086.1 EDO16541.1 - 0.17 11.4 1.2 0.89 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EDO16541.1 - 0.27 11.5 4.8 5.4 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fib_alpha PF08702.5 EDO16541.1 - 0.28 11.3 2.5 0.63 10.1 1.8 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Hexapep PF00132.19 EDO16542.1 - 3.3e-06 26.3 2.9 0.044 13.3 0.2 3.6 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EDO16542.1 - 2.9e-05 24.2 0.0 5.3e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 EDO16542.1 - 0.016 13.8 1.5 0.031 12.8 0.9 1.5 1 1 0 1 1 1 0 L-fucokinase Tox-GHH PF15636.1 EDO16542.1 - 0.042 13.4 0.7 0.088 12.4 0.0 1.8 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Hexapep_2 PF14602.1 EDO16542.1 - 2.4 7.7 4.9 7.3 6.2 1.4 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase UbiA PF01040.13 EDO16543.1 - 1.3e-22 80.2 14.7 1.8e-22 79.8 9.7 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family MitMem_reg PF13012.1 EDO16544.1 - 2.5e-39 133.8 0.9 2.5e-39 133.8 0.6 2.3 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EDO16544.1 - 5.8e-27 93.7 0.6 1.2e-26 92.6 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease KilA-N PF04383.8 EDO16544.1 - 0.62 9.7 0.0 0.62 9.7 0.0 2.3 2 0 0 2 2 2 0 KilA-N domain ATP_bind_1 PF03029.12 EDO16545.1 - 1.3e-78 263.8 0.1 1.7e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EDO16545.1 - 0.00028 21.6 2.2 0.00084 20.1 0.0 2.6 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO16545.1 - 0.00065 20.0 0.0 0.58 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EDO16545.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 EDO16545.1 - 0.0017 18.3 0.0 0.006 16.5 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EDO16545.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EDO16545.1 - 0.014 14.2 0.1 0.028 13.1 0.0 1.5 2 0 0 2 2 2 0 ArgK protein AAA_33 PF13671.1 EDO16545.1 - 0.04 13.8 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDO16545.1 - 0.045 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EDO16545.1 - 0.15 11.5 0.0 0.41 10.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TBCA PF02970.11 EDO16547.1 - 1.3e-28 98.9 6.6 1.6e-28 98.6 4.6 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Apolipoprotein PF01442.13 EDO16547.1 - 0.026 14.0 2.0 0.039 13.4 1.4 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain CENP-Q PF13094.1 EDO16547.1 - 0.03 14.3 4.6 0.13 12.2 3.2 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit rve_2 PF13333.1 EDO16547.1 - 0.04 13.9 1.3 0.42 10.7 0.1 2.2 2 0 0 2 2 2 0 Integrase core domain NusB PF01029.13 EDO16547.1 - 0.094 12.7 2.2 0.11 12.4 1.5 1.1 1 0 0 1 1 1 0 NusB family RasGAP_C PF03836.10 EDO16547.1 - 0.17 11.5 5.8 0.083 12.5 1.2 1.9 1 1 1 2 2 2 0 RasGAP C-terminus DUF342 PF03961.8 EDO16547.1 - 0.41 8.9 4.5 0.45 8.8 3.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EDO16547.1 - 0.58 9.7 5.0 0.75 9.3 3.4 1.2 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 EDO16549.1 - 9.1e-52 175.7 0.0 1.6e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16549.1 - 3.9e-21 75.2 0.0 5.7e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO16549.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDO16549.1 - 0.0047 15.9 0.0 0.016 14.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EDO16549.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family V_ATPase_I PF01496.14 EDO16550.1 - 9.5e-287 952.9 5.2 1.1e-286 952.7 3.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family 7TM_GPCR_Srt PF10321.4 EDO16550.1 - 0.013 14.2 0.6 0.013 14.2 0.4 3.2 3 0 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Srt DNA_pol3_beta PF00712.14 EDO16550.1 - 0.043 13.6 0.2 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain THP2 PF09432.5 EDO16550.1 - 0.34 10.7 4.0 0.9 9.3 0.9 2.7 2 1 0 2 2 2 0 Tho complex subunit THP2 MCPsignal PF00015.16 EDO16550.1 - 0.36 10.3 2.6 0.6 9.6 0.0 2.2 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain GHMP_kinases_N PF00288.21 EDO16551.1 - 4.2e-22 77.9 1.2 8e-22 77.0 0.8 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDO16551.1 - 2.2e-06 27.7 0.0 6.5e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Mtc PF03820.12 EDO16552.1 - 1.3e-121 404.9 0.4 1.5e-121 404.8 0.3 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier WD40 PF00400.27 EDO16553.1 - 1.4e-37 126.2 7.9 1.8e-07 30.7 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EDO16553.1 - 2.9e-23 81.6 0.1 6.3e-23 80.5 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EDO16553.1 - 8.4e-10 37.3 2.5 0.0053 14.9 0.1 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Abhydrolase_6 PF12697.2 EDO16554.1 - 3.8e-10 40.0 0.0 6e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO16554.1 - 6.8e-08 32.3 0.0 3.7e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO16554.1 - 1.3e-05 24.9 0.0 2.3e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EDO16554.1 - 0.00022 20.3 0.0 0.00052 19.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Cutinase PF01083.17 EDO16554.1 - 0.001 18.8 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 EDO16554.1 - 0.0017 17.9 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Tubulin_3 PF14881.1 EDO16555.1 - 2.1e-28 99.0 0.1 4.2e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EDO16555.1 - 8.5e-19 67.7 0.4 1.8e-18 66.6 0.2 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EDO16555.1 - 1.7e-07 31.3 0.0 0.0014 18.5 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain IPPT PF01715.12 EDO16556.1 - 1.5e-85 286.2 0.6 2.5e-85 285.5 0.4 1.3 1 0 0 1 1 1 1 IPP transferase AAA_18 PF13238.1 EDO16556.1 - 3.1e-06 27.4 0.4 3.1e-06 27.4 0.3 2.7 2 2 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO16556.1 - 6.4e-06 26.9 0.1 6.4e-06 26.9 0.1 2.8 2 2 0 2 2 2 1 AAA domain IPT PF01745.11 EDO16556.1 - 0.00017 20.8 0.1 0.0018 17.4 0.0 2.6 2 1 1 3 3 3 1 Isopentenyl transferase AAA_33 PF13671.1 EDO16556.1 - 0.00035 20.4 0.0 0.0022 17.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EDO16556.1 - 0.0065 16.6 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 EDO16556.1 - 0.0092 15.8 0.7 2.4 8.0 0.0 3.1 4 0 0 4 4 4 1 Shikimate kinase Zeta_toxin PF06414.7 EDO16556.1 - 0.015 14.4 0.1 0.12 11.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 EDO16556.1 - 0.02 14.3 0.0 0.05 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 EDO16556.1 - 0.022 14.1 0.5 0.056 12.8 0.1 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.17 EDO16556.1 - 0.076 13.1 0.0 0.24 11.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EDO16556.1 - 1 9.6 3.6 1.1 9.5 1.4 2.1 2 1 0 2 2 2 0 ABC transporter PUF PF00806.14 EDO16557.1 - 0.00017 20.9 0.3 0.00017 20.9 0.2 2.9 3 0 0 3 3 3 1 Pumilio-family RNA binding repeat PGG PF13962.1 EDO16557.1 - 0.066 12.8 0.5 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function DnaJ PF00226.26 EDO16558.1 - 4.6e-28 96.7 1.8 7.2e-28 96.1 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EDO16558.1 - 1.6e-15 56.8 17.1 2.8e-15 56.1 11.9 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EDO16558.1 - 2.2e-09 37.0 0.2 5.9e-08 32.5 0.0 2.8 3 0 0 3 3 3 1 DnaJ C terminal domain HypA PF01155.14 EDO16558.1 - 0.25 11.0 11.6 1.2 8.9 0.8 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Glyco_hydro_72 PF03198.9 EDO16559.1 - 6.7e-124 412.9 3.6 1.2e-123 412.1 2.5 1.4 2 0 0 2 2 2 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EDO16559.1 - 2.2e-08 33.3 0.0 3.6e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EDO16559.1 - 0.025 13.7 0.1 0.11 11.7 0.1 2.0 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Tmemb_cc2 PF10267.4 EDO16559.1 - 0.11 11.0 7.0 0.18 10.3 4.9 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Herpes_capsid PF06112.6 EDO16559.1 - 7.2 6.6 14.6 12 5.8 10.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Pkinase PF00069.20 EDO16560.1 - 3.8e-44 150.8 5.3 1.2e-24 86.8 2.3 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16560.1 - 1.3e-13 50.6 3.5 2.7e-09 36.4 1.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EDO16560.1 - 0.012 14.4 0.6 0.026 13.3 0.1 1.6 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase HEM4 PF02602.10 EDO16561.1 - 7.5e-43 146.4 0.0 8.4e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TRAPPC10 PF12584.3 EDO16562.1 - 9.2e-19 67.3 0.0 2.4e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.2 EDO16562.1 - 6.1e-05 22.7 0.1 0.00048 19.8 0.0 2.4 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Foie-gras_1 PF11817.3 EDO16562.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 GHMP_kinases_N PF00288.21 EDO16564.1 - 4.2e-14 52.3 0.4 1.8e-13 50.3 0.3 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDO16564.1 - 0.0014 18.7 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal FSH1 PF03959.8 EDO16565.1 - 1.7e-59 200.8 0.0 1.9e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EDO16565.1 - 4.9e-09 36.0 0.0 6.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EDO16565.1 - 3.3e-05 23.4 0.0 0.00019 20.9 0.0 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EDO16565.1 - 3.4e-05 23.8 0.0 0.043 13.6 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family UCH PF00443.24 EDO16566.1 - 3.6e-57 193.5 4.7 5.1e-57 193.0 3.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO16566.1 - 1.2e-23 83.9 3.4 1.8e-23 83.3 2.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EDO16566.1 - 1.9e-12 47.1 10.8 1.9e-12 47.1 7.5 2.8 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Rhodanese PF00581.15 EDO16567.1 - 6e-15 55.5 0.0 7.6e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF947 PF06102.7 EDO16568.1 - 2e-43 148.1 26.1 2e-43 148.1 18.1 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF947) MRP_L53 PF10780.4 EDO16569.1 - 4e-22 77.9 0.1 5.5e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Thioredoxin PF00085.15 EDO16570.1 - 2.9e-21 75.0 0.0 7.7e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EDO16570.1 - 8e-05 22.5 0.1 0.00027 20.8 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO16570.1 - 9.7e-05 22.5 1.7 0.00021 21.4 0.1 2.3 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDO16570.1 - 0.00016 21.7 0.2 0.0064 16.5 0.0 2.8 2 1 1 3 3 3 1 Thioredoxin-like Glutaredoxin PF00462.19 EDO16570.1 - 0.042 13.8 0.1 0.16 11.9 0.1 2.0 1 0 0 1 1 1 0 Glutaredoxin NYD-SP28_assoc PF14775.1 EDO16571.1 - 0.053 13.2 0.3 0.36 10.5 0.1 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain DALR_1 PF05746.10 EDO16571.1 - 0.12 12.3 1.0 0.25 11.3 0.2 1.9 2 0 0 2 2 2 0 DALR anticodon binding domain BPL_LplA_LipB PF03099.14 EDO16573.1 - 4.1e-16 59.1 0.1 6.6e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family FHA PF00498.21 EDO16574.1 - 1.6e-17 63.3 0.2 3e-16 59.3 0.1 2.7 2 0 0 2 2 2 1 FHA domain Atg14 PF10186.4 EDO16574.1 - 0.0031 16.5 12.7 0.0061 15.5 8.8 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 CALCOCO1 PF07888.6 EDO16574.1 - 0.014 13.6 10.9 0.026 12.8 7.5 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Phage_GPO PF05929.6 EDO16574.1 - 0.045 13.0 5.6 0.087 12.0 3.9 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FUSC-like PF12805.2 EDO16574.1 - 3.5 6.4 6.5 2.6 6.8 3.4 1.5 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DASH_Spc19 PF08287.6 EDO16575.1 - 3.8e-43 146.7 11.7 4.3e-43 146.5 8.1 1.0 1 0 0 1 1 1 1 Spc19 SlyX PF04102.7 EDO16575.1 - 0.0011 19.3 8.4 0.34 11.3 0.0 3.2 3 0 0 3 3 3 2 SlyX AAA_23 PF13476.1 EDO16575.1 - 0.013 15.7 6.4 0.017 15.4 4.5 1.1 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 EDO16575.1 - 0.015 13.7 6.1 0.02 13.3 4.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF342) CENP-F_leu_zip PF10473.4 EDO16575.1 - 0.03 14.1 15.4 0.18 11.6 7.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EDO16575.1 - 0.051 12.6 9.1 0.052 12.5 4.2 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EDO16575.1 - 0.14 11.7 12.8 0.83 9.2 8.8 1.9 1 1 0 1 1 1 0 IncA protein Mnd1 PF03962.10 EDO16575.1 - 0.39 10.3 8.2 2.6 7.6 5.7 2.0 1 1 0 1 1 1 0 Mnd1 family GvpK PF05121.7 EDO16575.1 - 0.41 10.5 7.0 0.71 9.7 0.1 3.1 3 0 0 3 3 3 0 Gas vesicle protein K Phage_GP20 PF06810.6 EDO16575.1 - 0.43 10.0 12.6 2.6 7.4 1.1 3.0 2 1 1 3 3 3 0 Phage minor structural protein GP20 DUF4140 PF13600.1 EDO16575.1 - 0.68 10.4 9.1 2.9 8.3 1.4 2.7 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DASH_Dad2 PF08654.5 EDO16575.1 - 0.95 9.5 12.7 1 9.3 1.4 3.1 2 1 1 3 3 3 0 DASH complex subunit Dad2 Prefoldin PF02996.12 EDO16575.1 - 1.2 8.7 10.2 5.6 6.6 0.1 3.2 2 1 0 3 3 3 0 Prefoldin subunit Sas10_Utp3 PF04000.10 EDO16575.1 - 1.4 9.2 11.0 4.1 7.6 0.5 3.3 2 1 1 3 3 3 0 Sas10/Utp3/C1D family DUF4515 PF14988.1 EDO16575.1 - 1.5 8.4 12.2 1.1 8.8 6.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4515) H-kinase_dim PF02895.9 EDO16575.1 - 1.5 9.1 9.5 3.5 8.0 0.9 2.9 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF4047 PF13256.1 EDO16575.1 - 2 8.4 4.2 28 4.6 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4047) FlaC_arch PF05377.6 EDO16575.1 - 3.4 7.6 9.7 6 6.8 0.2 3.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) OmpH PF03938.9 EDO16575.1 - 3.6 7.5 7.3 11 5.9 5.0 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) ATG16 PF08614.6 EDO16575.1 - 4.3 7.1 13.9 16 5.2 9.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Syntaxin_2 PF14523.1 EDO16575.1 - 5.4 7.1 7.8 4.3 7.4 3.4 2.0 1 1 1 2 2 2 0 Syntaxin-like protein DivIC PF04977.10 EDO16575.1 - 5.5 6.5 9.3 6.6 6.3 0.5 3.2 3 0 0 3 3 3 0 Septum formation initiator SYCE1 PF15233.1 EDO16575.1 - 7.4 6.4 12.7 3.5 7.5 2.3 2.8 2 1 0 3 3 3 0 Synaptonemal complex central element protein 1 Val_tRNA-synt_C PF10458.4 EDO16575.1 - 8.7 6.5 12.5 2.4 8.2 0.5 2.9 2 1 1 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Spc24 PF08286.6 EDO16575.1 - 9.8 5.9 14.8 8.8 6.0 0.5 3.1 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Rogdi_lz PF10259.4 EDO16576.1 - 4.8e-85 284.9 5.2 5.5e-85 284.7 3.6 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Coq4 PF05019.8 EDO16577.1 - 3.5e-100 333.4 0.0 4.5e-100 333.1 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Aminotran_3 PF00202.16 EDO16578.1 - 7.5e-84 281.4 0.0 8.8e-84 281.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ATP-synt_F PF01990.12 EDO16579.1 - 6.1e-32 109.8 0.3 7.1e-32 109.6 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 EDO16579.1 - 0.014 14.3 0.1 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DUF257 PF03192.8 EDO16579.1 - 0.028 13.7 0.1 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 Tom37_C PF11801.3 EDO16580.1 - 0.037 13.9 0.2 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain tRNA_synt_1c_R2 PF04557.10 EDO16581.1 - 0.061 14.0 3.5 13 6.5 2.6 2.3 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Peptidase_S76 PF13611.1 EDO16581.1 - 0.38 10.8 3.3 0.58 10.2 2.3 1.3 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 DUF2852 PF11014.3 EDO16581.1 - 0.8 9.6 4.1 1.2 9.0 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Anillin PF08174.6 EDO16582.1 - 1.7e-14 54.0 0.2 1.7e-14 54.0 0.2 2.8 3 0 0 3 3 3 1 Cell division protein anillin PUF PF00806.14 EDO16583.1 - 2.5e-28 95.9 1.6 4.6e-05 22.6 0.0 6.5 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EDO16583.1 - 4e-05 23.1 0.0 0.00011 21.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EDO16583.1 - 0.00036 20.1 0.0 0.0011 18.5 0.0 1.8 1 0 0 1 1 1 1 Calcipressin RRM_5 PF13893.1 EDO16583.1 - 0.0032 17.2 0.0 0.0076 16.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO16583.1 - 0.058 13.3 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF-5_eIF-2B PF01873.12 EDO16584.1 - 3.3e-42 143.0 0.0 6.8e-42 142.0 0.0 1.6 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.13 EDO16584.1 - 4.4e-26 90.6 4.8 1.4e-25 89.0 0.0 3.0 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon TPR_2 PF07719.12 EDO16585.1 - 3.7e-08 32.6 0.2 1.3e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO16585.1 - 1.8e-07 30.4 0.3 6e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO16585.1 - 5.3e-07 28.9 0.0 2.8e-06 26.7 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EDO16585.1 - 7.4e-06 25.5 0.0 3.7e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 EDO16585.1 - 1.3e-05 25.7 0.0 0.014 16.0 0.0 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDO16585.1 - 7.1e-05 22.7 0.0 0.35 11.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO16585.1 - 0.0024 17.5 0.0 0.0088 15.7 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDO16585.1 - 0.0037 17.5 0.0 0.014 15.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO16585.1 - 0.0041 17.0 0.0 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO16585.1 - 0.032 14.6 0.0 0.17 12.4 0.0 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EDO16585.1 - 0.046 14.3 0.0 0.17 12.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EDO16585.1 - 0.064 13.2 0.2 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EDO16585.1 - 0.071 13.2 0.2 0.58 10.3 0.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TIP41 PF04176.8 EDO16586.1 - 3.5e-71 238.2 2.7 4.9e-71 237.7 1.8 1.2 1 0 0 1 1 1 1 TIP41-like family Evr1_Alr PF04777.8 EDO16587.1 - 4.3e-26 90.6 0.2 7e-26 89.9 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Gln-synt_C PF00120.19 EDO16589.1 - 7.2e-65 218.7 0.0 8.6e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EDO16589.1 - 9.9e-21 73.1 0.0 1.7e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Actin PF00022.14 EDO16590.1 - 1.6e-47 161.8 0.6 2.2e-37 128.4 0.0 2.1 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EDO16590.1 - 0.00021 19.9 0.0 0.051 12.1 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein NuA4 PF09340.5 EDO16591.1 - 2.5e-25 87.9 1.4 3.6e-25 87.4 0.9 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF972 PF06156.8 EDO16591.1 - 0.01 16.1 0.8 0.014 15.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Borrelia_lipo_1 PF05714.6 EDO16591.1 - 0.014 14.4 5.2 0.019 14.0 3.6 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein YtzH PF14165.1 EDO16591.1 - 0.034 14.3 0.4 0.034 14.3 0.3 1.5 2 0 0 2 2 2 0 YtzH-like protein Phage_connect_1 PF05135.8 EDO16591.1 - 0.037 14.2 0.1 0.05 13.7 0.1 1.2 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein FCH PF00611.18 EDO16591.1 - 0.042 14.0 4.9 0.043 13.9 3.4 1.3 1 1 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF1635 PF07795.6 EDO16591.1 - 0.14 11.4 1.4 0.16 11.3 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Aida_N PF08910.5 EDO16591.1 - 0.46 10.7 2.6 0.65 10.2 1.6 1.5 1 1 0 1 1 1 0 Aida N-terminus Vma12 PF11712.3 EDO16591.1 - 0.64 9.7 3.9 0.76 9.4 2.7 1.4 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Seryl_tRNA_N PF02403.17 EDO16591.1 - 0.68 9.9 4.7 1.2 9.1 3.1 1.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1227 PF06777.6 EDO16591.1 - 0.91 9.2 5.1 1.3 8.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1227) IncA PF04156.9 EDO16591.1 - 1.3 8.5 7.8 2.2 7.8 5.4 1.3 1 0 0 1 1 1 0 IncA protein UPF0242 PF06785.6 EDO16591.1 - 2.9 6.4 5.5 3.7 6.1 3.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) AIM24 PF01987.12 EDO16592.1 - 1.3e-11 44.3 0.0 3.5e-11 42.9 0.0 1.7 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 tRNA-synt_His PF13393.1 EDO16593.1 - 2.4e-40 138.5 0.0 3e-39 134.9 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EDO16593.1 - 1.2e-19 70.5 0.0 6.5e-19 68.1 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO16593.1 - 4e-13 49.1 0.0 7.7e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EDO16593.1 - 0.0014 17.4 0.0 0.018 13.8 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.2 EDO16593.1 - 0.0026 16.9 0.0 0.0065 15.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.15 EDO16593.1 - 0.037 13.2 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) OGG_N PF07934.7 EDO16593.1 - 0.058 13.3 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 8-oxoguanine DNA glycosylase, N-terminal domain Ribosomal_60s PF00428.14 EDO16593.1 - 0.53 10.7 8.8 2.2 8.7 0.9 3.4 3 0 0 3 3 3 0 60s Acidic ribosomal protein IDO PF01231.13 EDO16594.1 - 2.1e-149 497.5 0.0 3.7e-149 496.7 0.0 1.4 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase Cid2 PF09774.4 EDO16595.1 - 3.4e-31 108.4 2.9 4.3e-31 108.0 2.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 CTNNBL PF08216.6 EDO16595.1 - 0.15 11.6 4.1 1.1 8.8 0.1 2.7 3 0 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear Pkinase PF00069.20 EDO16596.1 - 1.5e-62 211.1 0.0 3.6e-62 209.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16596.1 - 8.2e-35 120.1 0.0 1.7e-34 119.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EDO16596.1 - 1.4e-26 91.9 27.0 3.8e-15 55.3 7.2 3.1 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 EDO16596.1 - 1e-17 63.5 35.3 3.5e-10 39.4 10.0 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EDO16596.1 - 8.1e-13 48.6 2.9 3.3e-12 46.7 2.0 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDO16596.1 - 0.00093 18.2 0.1 0.0036 16.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF4206 PF13901.1 EDO16596.1 - 7.3 6.0 32.7 0.15 11.6 3.9 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4206) zf-RING_2 PF13639.1 EDO16597.1 - 0.2 11.5 10.4 0.099 12.4 1.9 3.3 3 0 0 3 3 3 0 Ring finger domain zf-HC5HC2H_2 PF13832.1 EDO16598.1 - 1.1e-32 112.2 18.0 5.3e-32 110.0 8.1 2.8 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EDO16598.1 - 1.6e-27 95.4 9.1 1.6e-27 95.4 6.3 3.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EDO16598.1 - 2.8e-13 48.9 2.5 2.8e-13 48.9 1.7 2.9 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EDO16598.1 - 1.1e-09 37.7 5.1 1.1e-09 37.7 3.6 2.9 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.4 EDO16598.1 - 5.8e-08 33.1 2.5 8e-08 32.6 0.7 2.0 2 0 0 2 2 2 1 Enhancer of polycomb-like C1_1 PF00130.17 EDO16598.1 - 0.00072 19.2 0.6 0.00072 19.2 0.4 2.8 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EDO16598.1 - 0.00091 18.9 24.7 0.0074 16.0 1.8 2.8 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 DUF1154 PF06631.6 EDO16598.1 - 0.049 13.2 0.4 0.13 11.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) zf-RING-like PF08746.6 EDO16598.1 - 1 9.3 25.1 0.77 9.8 7.5 3.1 2 0 0 2 2 2 0 RING-like domain zf-PHD-like PF15446.1 EDO16598.1 - 2.7 7.2 18.4 0.015 14.5 3.8 2.7 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Arrestin_C PF02752.17 EDO16599.1 - 6.5e-15 55.4 7.5 4.4e-13 49.5 0.2 3.4 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EDO16599.1 - 0.0015 18.4 0.1 0.067 13.0 0.1 2.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Pro_isomerase PF00160.16 EDO16600.1 - 3.3e-47 160.5 0.1 3.8e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sybindin PF04099.7 EDO16601.1 - 2.5e-19 69.3 0.5 2.9e-19 69.1 0.3 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EDO16601.1 - 0.0014 18.5 0.2 0.0016 18.2 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region OstA_C PF04453.9 EDO16601.1 - 0.0017 17.5 0.6 0.0021 17.2 0.4 1.1 1 0 0 1 1 1 1 Organic solvent tolerance protein EAP30 PF04157.11 EDO16601.1 - 0.1 11.7 0.0 0.27 10.3 0.0 1.5 1 1 1 2 2 2 0 EAP30/Vps36 family HMG-CoA_red PF00368.13 EDO16602.1 - 9.5e-159 528.0 0.7 1.3e-158 527.5 0.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EDO16602.1 - 2.6e-43 147.3 1.6 5.7e-43 146.2 1.1 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EDO16602.1 - 3.5e-07 29.7 4.9 8.9e-07 28.4 3.4 1.8 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation DUF2976 PF11190.3 EDO16602.1 - 7.7 6.1 9.8 3.1 7.3 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Piwi PF02171.12 EDO16603.1 - 1.9e-64 217.5 0.9 1.9e-64 217.5 0.6 2.2 3 0 0 3 3 3 1 Piwi domain PAZ PF02170.17 EDO16603.1 - 1.9e-09 36.9 0.1 5.4e-09 35.4 0.1 1.8 1 0 0 1 1 1 1 PAZ domain MIP-T3 PF10243.4 EDO16603.1 - 0.23 9.8 67.7 0.36 9.2 46.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 EDO16603.1 - 1.2 7.2 55.7 1.9 6.5 38.6 1.2 1 0 0 1 1 1 0 Utp14 protein Ribosomal_L6e PF01159.14 EDO16604.1 - 5.8e-39 132.6 2.5 8.1e-39 132.2 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Med25 PF11232.3 EDO16604.1 - 0.06 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 vATP-synt_AC39 PF01992.11 EDO16605.1 - 1.4e-82 277.5 0.2 1.6e-82 277.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Cyt-b5 PF00173.23 EDO16606.1 - 6.2e-10 38.7 0.0 9.2e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BAR PF03114.13 EDO16607.1 - 2.6e-12 46.7 5.6 6e-12 45.5 3.9 1.6 1 0 0 1 1 1 1 BAR domain Val_tRNA-synt_C PF10458.4 EDO16607.1 - 0.29 11.2 3.6 4.8 7.3 0.8 2.4 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Dak1 PF02733.12 EDO16608.1 - 2.4e-136 453.6 1.4 3.3e-136 453.1 1.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EDO16608.1 - 1.5e-46 158.2 0.7 3.5e-46 157.0 0.5 1.7 1 0 0 1 1 1 1 DAK2 domain SSrecog PF03531.9 EDO16609.1 - 6.5e-69 231.6 5.0 4.4e-67 225.6 2.4 2.7 2 1 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EDO16609.1 - 6.6e-31 106.1 0.2 1.7e-27 95.2 0.0 3.4 3 0 0 3 3 3 2 Histone chaperone Rttp106-like TfuA PF07812.7 EDO16609.1 - 0.087 12.2 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 TfuA-like protein IBR PF01485.16 EDO16610.1 - 1.3e-13 50.5 29.6 1.4e-08 34.4 2.5 4.0 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EDO16610.1 - 2e-05 24.3 6.9 2e-05 24.3 4.8 4.5 3 2 2 5 5 5 2 Ring finger domain zf-C3HC4_2 PF13923.1 EDO16610.1 - 0.011 15.7 10.2 0.011 15.7 7.1 4.8 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) BsuPI PF12690.2 EDO16611.1 - 0.1 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Intracellular proteinase inhibitor SUR7 PF06687.7 EDO16611.1 - 0.92 9.0 15.1 19 4.7 10.5 2.6 1 1 0 1 1 1 0 SUR7/PalI family BAH PF01426.13 EDO16612.1 - 2.7e-13 49.7 1.1 7.2e-13 48.3 0.8 1.8 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 EDO16612.1 - 0.00066 19.8 0.0 0.0032 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDO16612.1 - 0.0037 17.2 0.0 0.014 15.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Ras PF00071.17 EDO16613.1 - 4.9e-31 107.3 0.2 5.9e-31 107.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO16613.1 - 1.3e-18 67.6 0.1 2.9e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EDO16613.1 - 2.6e-06 26.7 0.5 3.2e-06 26.4 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EDO16613.1 - 1.8e-05 24.0 0.1 2.5e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO16613.1 - 6.1e-05 22.5 0.2 0.00051 19.5 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO16613.1 - 0.026 14.4 0.1 0.041 13.8 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 EDO16613.1 - 0.04 13.1 0.1 0.057 12.6 0.1 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MobB PF03205.9 EDO16613.1 - 0.12 12.1 0.1 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B THOC7 PF05615.8 EDO16614.1 - 1.2e-30 106.5 8.4 1.2e-30 106.5 5.8 3.2 2 1 0 3 3 3 1 Tho complex subunit 7 Phage_endo_I PF05367.6 EDO16614.1 - 0.011 15.1 0.6 0.028 13.8 0.0 2.0 2 0 0 2 2 2 0 Phage endonuclease I IL2 PF00715.12 EDO16614.1 - 0.079 12.6 5.0 3.4 7.3 0.1 3.0 1 1 2 3 3 3 0 Interleukin 2 BUD22 PF09073.5 EDO16614.1 - 3.6 6.5 28.7 6.3 5.7 19.9 1.4 1 0 0 1 1 1 0 BUD22 Sec39 PF08314.6 EDO16615.1 - 6.7e-182 606.1 22.0 7.6e-182 605.9 15.2 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 PIF1 PF05970.9 EDO16616.1 - 2.5e-61 207.6 10.5 2.3e-60 204.4 1.2 3.0 2 1 0 2 2 2 1 PIF1-like helicase AAA_30 PF13604.1 EDO16616.1 - 3.8e-18 65.7 0.0 6.3e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO16616.1 - 3.1e-06 27.3 0.0 9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EDO16616.1 - 8.7e-06 24.9 0.0 1.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EDO16616.1 - 1.7e-05 24.5 0.2 3.3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EDO16616.1 - 0.00021 20.5 0.1 0.00049 19.3 0.1 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 EDO16616.1 - 0.0047 17.1 0.1 0.02 15.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EDO16616.1 - 0.0065 15.7 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DEAD PF00270.24 EDO16616.1 - 0.0069 15.8 0.3 0.62 9.5 0.1 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 EDO16616.1 - 0.015 14.1 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein UvrD_C_2 PF13538.1 EDO16616.1 - 0.031 14.4 0.0 0.47 10.6 0.0 2.7 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_29 PF13555.1 EDO16616.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helicase_RecD PF05127.9 EDO16616.1 - 0.055 13.1 0.3 0.78 9.3 0.2 2.5 1 1 0 1 1 1 0 Helicase AAA_11 PF13086.1 EDO16616.1 - 0.073 12.6 4.9 6.6 6.2 0.0 3.7 3 1 0 4 4 4 0 AAA domain ABC_tran PF00005.22 EDO16616.1 - 0.095 13.0 0.8 0.61 10.3 0.1 2.4 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.13 EDO16616.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Aminotran_3 PF00202.16 EDO16617.1 - 6.9e-108 360.4 0.0 8.1e-108 360.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EDO16617.1 - 0.00028 20.1 0.0 0.00057 19.1 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase RNR_inhib PF08591.5 EDO16618.1 - 1.3e-11 45.2 4.5 2.1e-05 25.3 0.0 2.2 1 1 1 2 2 2 2 Ribonucleotide reductase inhibitor CitT PF12431.3 EDO16618.1 - 0.082 12.9 0.2 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator Myb_DNA-bind_5 PF13873.1 EDO16619.1 - 4.5 7.2 11.3 0.36 10.7 0.5 3.9 4 0 0 4 4 4 0 Myb/SANT-like DNA-binding domain SEN1_N PF12726.2 EDO16620.1 - 3.1e-230 766.0 26.1 5.4e-230 765.2 18.1 1.4 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EDO16620.1 - 1.5e-69 234.1 0.2 1.5e-69 234.1 0.2 3.6 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.1 EDO16620.1 - 8.2e-60 201.6 0.0 8.2e-60 201.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EDO16620.1 - 2.3e-11 43.2 0.1 7.4e-11 41.6 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EDO16620.1 - 2.3e-07 30.6 0.0 0.00023 20.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Histone PF00125.19 EDO16622.1 - 6.4e-26 90.2 0.0 8.8e-26 89.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDO16622.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDO16623.1 - 2.9e-22 78.5 0.3 4.1e-22 78.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDO16623.1 - 8.8e-07 28.8 0.1 1.7e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EDO16623.1 - 0.0011 19.2 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A VIT1 PF01988.14 EDO16624.1 - 1.4e-55 188.0 0.2 1.7e-55 187.8 0.1 1.1 1 0 0 1 1 1 1 VIT family Rsa3 PF14615.1 EDO16625.1 - 1.7e-21 75.2 0.5 2.9e-21 74.4 0.4 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 SR-25 PF10500.4 EDO16625.1 - 0.062 12.7 7.8 0.073 12.5 5.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BetaGal_dom3 PF13363.1 EDO16625.1 - 0.083 12.3 0.2 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 TFIIS_M PF07500.9 EDO16625.1 - 6.6 6.8 10.5 0.53 10.3 0.9 3.0 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS), central domain CRF1 PF10380.4 EDO16626.1 - 2.1e-33 115.2 3.4 2.1e-33 115.2 2.4 6.2 4 2 0 4 4 4 1 Transcription factor CRF1 PRKCSH-like PF12999.2 EDO16627.1 - 1.4e-41 142.0 3.7 1.4e-41 142.0 2.5 2.5 3 1 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EDO16627.1 - 5.8e-19 68.0 4.4 5.8e-18 64.8 3.0 2.6 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein Atg14 PF10186.4 EDO16627.1 - 0.0038 16.2 0.5 0.65 8.8 0.0 2.3 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 LRR_8 PF13855.1 EDO16627.1 - 0.022 14.4 2.8 0.61 9.8 0.2 3.0 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 EDO16627.1 - 0.022 14.3 2.6 2.8 7.6 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) SlyX PF04102.7 EDO16627.1 - 0.15 12.4 3.7 7.4 7.0 0.4 2.8 2 0 0 2 2 2 0 SlyX ADIP PF11559.3 EDO16627.1 - 0.17 11.8 8.9 0.17 11.7 0.4 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Ldl_recept_a PF00057.13 EDO16627.1 - 1.5 8.8 15.9 3.3 7.7 2.3 2.5 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A TPR_MLP1_2 PF07926.7 EDO16627.1 - 1.8 8.3 13.7 3.6 7.3 2.1 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.10 EDO16627.1 - 2.4 7.7 9.8 3.1 7.3 0.7 2.8 2 0 0 2 2 2 0 Septum formation initiator F-box-like PF12937.2 EDO16628.1 - 2e-07 30.6 0.2 3.6e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO16628.1 - 2.1e-05 24.0 0.6 5.2e-05 22.7 0.4 1.7 1 0 0 1 1 1 1 F-box domain KaiC PF06745.8 EDO16628.1 - 0.19 10.7 6.7 1.8 7.6 0.2 2.4 2 0 0 2 2 2 0 KaiC Septin PF00735.13 EDO16630.1 - 1.9e-68 230.5 0.2 3.8e-68 229.5 0.1 1.5 1 0 0 1 1 1 1 Septin Dynamin_N PF00350.18 EDO16630.1 - 0.00025 20.9 1.0 0.0014 18.4 0.0 2.4 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EDO16630.1 - 0.0074 16.2 0.3 0.029 14.3 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EDO16630.1 - 0.0093 15.8 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EDO16630.1 - 0.012 16.0 0.0 0.049 14.1 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EDO16630.1 - 0.018 14.5 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EDO16630.1 - 0.018 15.3 0.2 0.055 13.7 0.0 1.9 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 EDO16630.1 - 0.021 13.9 0.0 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 EDO16630.1 - 0.037 13.1 0.0 0.079 12.0 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Mg_chelatase PF01078.16 EDO16630.1 - 0.048 12.8 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Glutaredoxin2_C PF04399.8 EDO16630.1 - 0.17 11.5 0.9 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Rad9_Rad53_bind PF08605.5 EDO16632.1 - 9.8e-38 128.9 0.1 2e-37 127.9 0.1 1.5 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EDO16632.1 - 1.2e-08 35.0 2.0 1.7e-07 31.2 0.3 3.4 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF3403 PF11883.3 EDO16632.1 - 0.94 9.7 7.6 0.62 10.3 0.5 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) zf-C2H2 PF00096.21 EDO16633.1 - 1.1e-08 34.8 12.7 4.8e-05 23.4 1.1 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO16633.1 - 2.4e-07 30.7 10.0 4.8e-06 26.6 4.2 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO16633.1 - 0.0013 18.8 23.0 0.0037 17.4 1.7 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EDO16633.1 - 0.0049 17.0 3.5 1.1 9.5 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EDO16633.1 - 0.3 11.0 7.7 0.63 10.0 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Aha1_N PF09229.6 EDO16634.1 - 1.1e-38 132.1 1.1 3.4e-38 130.5 0.6 2.0 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EDO16634.1 - 4.6e-11 42.8 0.1 9.6e-11 41.8 0.1 1.6 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF3362 PF11842.3 EDO16634.1 - 0.069 13.0 0.2 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) Fungal_trans_2 PF11951.3 EDO16635.1 - 1.5e-11 43.4 0.8 4.2e-11 42.0 0.5 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO16635.1 - 7e-08 32.2 12.7 1.1e-07 31.6 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.17 EDO16636.1 - 1.2e-50 171.0 0.0 1.4e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO16636.1 - 1.3e-13 51.4 0.0 1.7e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO16636.1 - 3e-07 29.8 0.0 3.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Thymidylate_kin PF02223.12 EDO16637.1 - 1.7e-37 128.6 0.0 2e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_33 PF13671.1 EDO16637.1 - 0.0059 16.4 0.0 0.0094 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO16637.1 - 0.0062 16.8 0.3 0.015 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 EDO16637.1 - 0.0069 16.0 0.0 0.0095 15.5 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 EDO16637.1 - 0.062 14.1 0.2 0.12 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 EDO16638.1 - 5.7e-40 137.1 0.0 1.2e-39 136.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16638.1 - 5.4e-15 55.1 0.0 9.2e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO16638.1 - 0.0022 17.0 0.0 0.0056 15.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO16638.1 - 0.19 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_binding_1 PF00175.16 EDO16639.1 - 1.2e-22 80.5 0.0 1.8e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EDO16639.1 - 1.8e-19 69.6 0.0 3.1e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EDO16639.1 - 1.6e-10 41.1 0.0 1.6e-07 31.3 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EDO16639.1 - 0.14 12.1 0.0 0.61 10.0 0.0 2.0 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain SID PF11778.3 EDO16640.1 - 2e-55 186.4 7.7 2e-55 186.4 5.3 4.5 3 1 0 4 4 4 1 Septation initiation Reo_sigmaC PF04582.7 EDO16640.1 - 0.00017 20.9 59.1 0.0021 17.3 8.8 6.0 3 3 3 6 6 6 5 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EDO16640.1 - 0.0081 15.9 11.1 0.0081 15.9 7.7 14.3 4 2 13 17 17 17 4 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EDO16640.1 - 0.021 14.6 123.7 0.13 12.0 2.8 7.6 2 2 4 7 7 7 0 Autophagy protein 16 (ATG16) DUF641 PF04859.7 EDO16640.1 - 0.55 9.9 63.1 1.5 8.6 2.9 9.4 3 3 6 10 10 10 0 Plant protein of unknown function (DUF641) SlyX PF04102.7 EDO16640.1 - 1.3 9.4 66.4 0.2 12.0 0.8 11.2 4 3 9 14 14 14 0 SlyX DnaJ PF00226.26 EDO16641.1 - 1.5e-25 88.7 0.2 4.8e-25 87.0 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 EDO16641.1 - 2.7e-11 43.2 9.9 2.1e-09 37.2 1.6 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EDO16641.1 - 1.6e-06 28.1 7.5 0.0039 17.2 1.3 3.1 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EDO16641.1 - 3.2e-06 27.1 5.6 0.014 15.7 0.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 EDO16641.1 - 5.7e-06 26.3 2.5 5.7e-06 26.3 1.7 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EDO16641.1 - 0.00017 21.6 1.9 0.021 15.1 0.3 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDO16641.1 - 0.2 11.6 7.4 2.2 8.3 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-LYAR PF08790.6 EDO16641.1 - 0.38 10.5 2.9 0.21 11.3 0.3 1.9 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger GST_C PF00043.20 EDO16642.1 - 3.4e-20 71.8 0.6 2.4e-19 69.0 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EDO16642.1 - 2.2e-16 59.7 0.0 6.2e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EDO16642.1 - 1.8e-08 34.2 0.0 4.3e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EDO16642.1 - 3.6e-08 33.5 0.0 7.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EDO16642.1 - 4.8e-05 23.1 0.0 9.2e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GAGA_bind PF06217.7 EDO16642.1 - 0.29 11.0 16.6 0.4 10.5 11.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Suf PF05843.9 EDO16642.1 - 0.44 10.2 22.6 0.76 9.4 15.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4011 PF13195.1 EDO16642.1 - 0.55 10.2 9.3 0.95 9.4 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4011) RR_TM4-6 PF06459.7 EDO16642.1 - 0.95 9.3 15.8 1.3 8.8 11.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.4 EDO16642.1 - 1.5 6.9 45.8 1.8 6.6 31.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FimP PF09766.4 EDO16642.1 - 2.6 7.0 35.0 8.3 5.3 23.2 2.0 2 0 0 2 2 2 0 Fms-interacting protein DDHD PF02862.12 EDO16642.1 - 4.1 7.1 19.0 6.6 6.4 13.2 1.3 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 EDO16642.1 - 4.2 5.9 12.2 5.8 5.5 8.4 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) TFIIA PF03153.8 EDO16642.1 - 5.4 6.8 40.9 7.3 6.3 28.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FLO_LFY PF01698.11 EDO16642.1 - 5.6 5.7 18.0 7.8 5.2 12.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein SprA-related PF12118.3 EDO16642.1 - 6.3 6.0 44.7 9.3 5.4 31.0 1.1 1 0 0 1 1 1 0 SprA-related family LMBR1 PF04791.11 EDO16642.1 - 6.4 5.2 6.8 8 4.9 4.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Band_3_cyto PF07565.8 EDO16642.1 - 7.4 5.9 18.9 11 5.4 13.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RbsD_FucU PF05025.8 EDO16642.1 - 9.6 6.5 11.0 89 3.3 0.0 2.4 2 0 0 2 2 2 0 RbsD / FucU transport protein family Elongin_A PF06881.6 EDO16643.1 - 8e-16 58.3 0.2 8e-16 58.3 0.1 3.3 3 1 1 4 4 4 2 RNA polymerase II transcription factor SIII (Elongin) subunit A Globin PF00042.17 EDO16644.1 - 2.2e-05 24.7 0.0 6.3e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Globin RhoGAP PF00620.22 EDO16645.1 - 3.4e-38 130.6 1.9 8.1e-38 129.4 0.2 2.5 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EDO16645.1 - 1.6e-32 111.3 48.3 5.3e-13 48.8 3.9 4.5 4 0 0 4 4 4 4 LIM domain Cytochrome_C7 PF14522.1 EDO16645.1 - 0.75 9.4 11.5 2.5 7.7 0.3 3.1 2 0 0 2 2 2 0 Cytochrome c7 Auto_anti-p27 PF06677.7 EDO16645.1 - 1.3 8.8 7.9 1.3 8.8 0.0 3.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ATG2_CAD PF13329.1 EDO16646.1 - 1.8e-34 118.5 1.4 1.8e-34 118.5 1.0 4.2 5 1 0 5 5 5 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EDO16646.1 - 3.1e-29 101.0 0.1 7.7e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Epimerase PF01370.16 EDO16647.1 - 8.3e-20 71.2 0.0 1.1e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EDO16647.1 - 1.1e-13 50.5 0.0 1.5e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EDO16647.1 - 3.4e-10 39.2 0.1 2.7e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EDO16647.1 - 5.6e-10 39.5 0.1 1.6e-09 38.0 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EDO16647.1 - 9.2e-08 32.1 0.0 2.5e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EDO16647.1 - 3.6e-05 23.1 0.1 0.00031 20.0 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EDO16647.1 - 5.8e-05 22.1 0.1 0.00011 21.2 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EDO16647.1 - 0.0001 22.0 0.0 0.0003 20.4 0.0 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EDO16647.1 - 0.01 15.9 0.1 0.018 15.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EDO16647.1 - 0.017 15.4 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EDO16647.1 - 0.021 15.2 0.0 0.053 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PTR2 PF00854.16 EDO16648.1 - 5.7e-60 203.0 18.5 5.7e-60 203.0 12.8 2.1 1 1 1 2 2 2 2 POT family Arc_PepC_II PF06847.6 EDO16648.1 - 0.43 11.0 3.5 1.3 9.4 0.0 2.9 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II ADH_N PF08240.7 EDO16650.1 - 2.5e-25 88.3 6.5 4.4e-25 87.5 4.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO16650.1 - 2.8e-16 59.2 0.0 5e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDO16650.1 - 5.7e-07 28.8 0.0 9.5e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF364 PF04016.7 EDO16650.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF364) ADH_zinc_N_2 PF13602.1 EDO16650.1 - 0.0037 18.1 0.0 0.006 17.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 EDO16650.1 - 0.0091 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EDO16650.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EDO16650.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 EDO16650.1 - 0.097 12.6 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Flocculin PF00624.13 EDO16651.1 - 2.3e-167 542.6 764.5 8.6e-13 47.8 9.0 114.5 40 3 74 114 114 114 32 Flocculin repeat Pox_A21 PF05323.7 EDO16651.1 - 0.51 10.7 4.0 2.6e+03 -1.2 0.0 9.0 7 4 4 10 10 10 0 Poxvirus A21 Protein Pox_A21 PF05323.7 EDO16652.1 - 0.15 12.4 8.2 5e+03 -2.2 0.0 11.7 2 2 0 3 3 3 0 Poxvirus A21 Protein CBF PF03914.12 EDO16654.1 - 5.6e-45 152.7 0.9 5.6e-45 152.7 0.6 3.0 3 0 0 3 3 3 1 CBF/Mak21 family UQ_con PF00179.21 EDO16655.1 - 1.8e-51 173.2 0.0 2.1e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO16655.1 - 4.3e-05 23.2 0.0 5.1e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EDO16655.1 - 0.00024 20.9 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EDO16655.1 - 0.0098 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 UEV domain Bromodomain PF00439.20 EDO16656.1 - 1e-16 60.5 0.3 3.7e-16 58.8 0.2 2.0 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EDO16656.1 - 1.3e-07 31.2 0.0 5.4e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 Bromodomain associated PRKCSH PF07915.8 EDO16657.1 - 1.1e-11 45.3 0.8 1.1e-11 45.3 0.6 3.4 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein MtrG PF04210.8 EDO16657.1 - 0.12 12.0 0.0 0.85 9.3 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G PBP1_TM PF14812.1 EDO16658.1 - 0.027 14.7 1.0 0.059 13.6 0.7 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA PF00004.24 EDO16659.1 - 2e-52 176.8 0.0 1.6e-38 131.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EDO16659.1 - 3e-14 52.7 0.0 2.7e-13 49.6 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 EDO16659.1 - 7.4e-10 39.0 0.5 0.00088 19.4 0.2 3.4 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EDO16659.1 - 9.7e-09 34.8 0.3 0.0034 17.0 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_16 PF13191.1 EDO16659.1 - 3.5e-08 33.6 0.0 0.0079 16.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 EDO16659.1 - 1e-07 31.0 0.1 0.0057 15.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 EDO16659.1 - 1.1e-07 32.6 0.1 0.017 15.9 0.1 2.7 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EDO16659.1 - 7e-07 28.8 0.2 0.05 13.0 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EDO16659.1 - 7.2e-07 28.5 0.0 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 EDO16659.1 - 7.3e-07 28.7 1.3 1.7e-06 27.5 0.2 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EDO16659.1 - 2.2e-06 27.5 0.0 0.0094 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EDO16659.1 - 2.3e-06 27.3 0.0 0.0016 18.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EDO16659.1 - 2.6e-06 27.3 0.0 0.056 13.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain PhoH PF02562.11 EDO16659.1 - 3e-06 26.6 0.0 0.0039 16.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein RuvB_N PF05496.7 EDO16659.1 - 1e-05 24.6 0.3 0.069 12.1 0.1 3.0 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus ABC_tran PF00005.22 EDO16659.1 - 1.3e-05 25.4 0.2 0.028 14.6 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_2 PF07724.9 EDO16659.1 - 1.4e-05 25.1 0.0 0.0013 18.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EDO16659.1 - 1.8e-05 25.0 0.0 0.021 15.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EDO16659.1 - 1.8e-05 24.4 2.1 0.025 14.2 0.0 3.6 4 1 0 4 4 4 1 NACHT domain RNA_helicase PF00910.17 EDO16659.1 - 3.3e-05 24.0 0.0 0.11 12.7 0.0 2.9 3 0 0 3 3 2 2 RNA helicase NB-ARC PF00931.17 EDO16659.1 - 7e-05 21.8 0.0 0.082 11.7 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain DUF2075 PF09848.4 EDO16659.1 - 8.7e-05 21.6 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 EDO16659.1 - 8.9e-05 22.0 0.0 0.21 11.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 EDO16659.1 - 0.00021 21.0 0.0 0.11 12.0 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_23 PF13476.1 EDO16659.1 - 0.00045 20.6 2.5 0.57 10.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain DEAD PF00270.24 EDO16659.1 - 0.0007 19.1 0.1 7.5 6.0 0.0 4.0 3 1 1 4 4 4 0 DEAD/DEAH box helicase ResIII PF04851.10 EDO16659.1 - 0.0012 18.7 0.0 0.52 10.1 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EDO16659.1 - 0.0012 18.4 3.6 0.45 10.0 0.3 3.0 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EDO16659.1 - 0.0014 17.7 0.0 0.88 8.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 EDO16659.1 - 0.002 17.7 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EDO16659.1 - 0.0023 17.6 0.6 3.1 7.4 0.0 3.2 2 1 1 3 3 3 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 EDO16659.1 - 0.0031 17.5 0.2 3.1 7.8 0.1 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 EDO16659.1 - 0.0035 16.7 6.6 1.2 8.4 0.3 3.8 2 2 1 4 4 4 2 AAA domain T2SE PF00437.15 EDO16659.1 - 0.0038 16.1 0.1 1.7 7.4 0.0 2.9 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_11 PF13086.1 EDO16659.1 - 0.0042 16.6 0.3 2.9 7.4 0.1 2.4 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EDO16659.1 - 0.0043 16.2 1.6 0.24 10.5 0.1 2.9 2 1 1 3 3 3 1 KaiC AAA_10 PF12846.2 EDO16659.1 - 0.0051 16.3 0.1 0.11 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain Parvo_NS1 PF01057.12 EDO16659.1 - 0.0053 15.6 0.0 2.5 6.8 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EDO16659.1 - 0.0094 15.5 0.1 2.6 7.7 0.0 2.7 3 0 0 3 3 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_3 PF07726.6 EDO16659.1 - 0.013 15.0 0.0 0.21 11.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EDO16659.1 - 0.016 15.1 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EDO16659.1 - 0.024 14.1 0.5 0.83 9.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain IPT PF01745.11 EDO16659.1 - 0.058 12.5 0.1 0.47 9.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase Recep_L_domain PF01030.19 EDO16660.1 - 2.4e-09 37.1 7.4 0.048 13.6 1.0 5.0 1 1 2 3 3 3 3 Receptor L domain LRR_9 PF14580.1 EDO16660.1 - 0.00031 20.3 0.1 0.00072 19.1 0.1 1.6 1 0 0 1 1 1 1 Leucine-rich repeat zf-C2H2 PF00096.21 EDO16661.1 - 5.6e-11 42.1 12.6 3.9e-06 26.8 1.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO16661.1 - 2.1e-08 34.0 10.8 1.5e-06 28.1 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO16661.1 - 7.1e-07 29.1 8.8 0.00039 20.5 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EDO16661.1 - 5.7e-05 23.1 6.2 0.00037 20.5 0.8 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDO16661.1 - 0.026 14.6 0.3 0.026 14.6 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EDO16661.1 - 0.039 14.0 0.2 0.039 14.0 0.1 2.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Ribosomal_L31 PF01197.13 EDO16661.1 - 0.068 13.1 1.3 4.3 7.4 0.6 3.4 2 1 0 2 2 2 0 Ribosomal protein L31 ARS2 PF04959.8 EDO16661.1 - 0.091 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Arsenite-resistance protein 2 SR-25 PF10500.4 EDO16661.1 - 0.16 11.4 7.3 0.33 10.3 5.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3399 PF11879.3 EDO16661.1 - 2.1 8.6 7.7 0.28 11.4 1.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) zf-BED PF02892.10 EDO16661.1 - 6.1 6.6 8.2 0.49 10.2 1.0 2.8 2 0 0 2 2 2 0 BED zinc finger Peptidase_M28 PF04389.12 EDO16662.1 - 1.7e-30 106.1 0.0 2.7e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 EDO16662.1 - 0.0018 17.1 0.0 0.006 15.3 0.0 1.8 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Ank_5 PF13857.1 EDO16663.1 - 2.1e-05 24.5 0.0 5.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO16663.1 - 0.00085 19.6 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDO16663.1 - 0.056 13.2 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Alg14 PF08660.6 EDO16664.1 - 1.3e-49 168.4 0.2 1.9e-49 167.9 0.1 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like His_Phos_1 PF00300.17 EDO16665.1 - 2.3e-18 66.7 0.0 2.7e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_1 PF00300.17 EDO16666.1 - 3.8e-16 59.5 0.0 5e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Thioredoxin_8 PF13905.1 EDO16667.1 - 0.02 14.9 0.0 0.24 11.5 0.0 2.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.15 EDO16667.1 - 0.045 13.4 0.0 0.13 11.9 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin Bunya_NS-S PF01104.12 EDO16667.1 - 0.24 10.8 1.5 0.33 10.4 1.1 1.3 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s AA_permease PF00324.16 EDO16668.1 - 3.9e-120 401.4 40.5 4.8e-120 401.1 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO16668.1 - 7.7e-33 113.6 42.9 9.6e-33 113.3 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO16669.1 - 1.5e-117 392.8 38.0 1.9e-117 392.5 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO16669.1 - 3.4e-29 101.6 40.1 4.4e-29 101.2 27.8 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4147 PF13660.1 EDO16669.1 - 0.09 11.8 0.1 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Phtf-FEM1B_bdg PF12129.3 EDO16669.1 - 3.2 7.0 7.5 1.1 8.5 3.0 1.8 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor Coprogen_oxidas PF01218.13 EDO16670.1 - 2.6e-125 416.8 0.3 2.9e-125 416.7 0.2 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase zf-C2H2_4 PF13894.1 EDO16671.1 - 1.3e-06 28.2 12.9 0.0038 17.4 0.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO16671.1 - 3.9e-05 23.7 3.1 3.9e-05 23.7 2.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EDO16671.1 - 0.00034 20.7 14.3 0.0046 17.2 0.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type FYRN PF05964.9 EDO16671.1 - 0.011 15.2 0.5 0.029 13.8 0.3 1.8 1 0 0 1 1 1 0 F/Y-rich N-terminus zf-met PF12874.2 EDO16671.1 - 0.023 14.8 5.6 0.056 13.6 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-RING-like PF08746.6 EDO16671.1 - 1.4 9.0 7.3 0.27 11.2 2.3 1.9 2 0 0 2 2 2 0 RING-like domain LVIVD PF08309.6 EDO16671.1 - 6.2 5.8 7.3 12 5.0 0.0 2.9 2 1 1 3 3 3 0 LVIVD repeat zf-RING_2 PF13639.1 EDO16672.1 - 6.5e-11 41.8 10.9 1e-10 41.2 7.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO16672.1 - 2.5e-08 33.8 8.6 4.3e-08 33.1 5.9 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EDO16672.1 - 1.7e-06 27.9 12.8 3.3e-06 26.9 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDO16672.1 - 5.6e-06 26.1 4.6 9.1e-06 25.4 3.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EDO16672.1 - 9.9e-06 25.1 12.7 1.8e-05 24.3 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO16672.1 - 1.1e-05 24.9 8.5 1.9e-05 24.1 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO16672.1 - 0.0023 17.6 10.5 0.0039 16.8 7.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.3 EDO16672.1 - 0.0055 16.6 9.0 0.13 12.2 6.2 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EDO16672.1 - 0.0057 16.3 3.9 0.017 14.8 2.6 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EDO16672.1 - 0.032 13.7 6.4 0.061 12.8 4.4 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-FCS PF06467.9 EDO16672.1 - 0.27 10.8 0.1 0.27 10.8 0.1 3.1 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif UPF0547 PF10571.4 EDO16672.1 - 0.5 10.0 9.4 5.2 6.8 2.6 2.6 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 RINGv PF12906.2 EDO16672.1 - 0.72 9.9 8.3 1.8 8.6 5.7 1.7 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EDO16672.1 - 0.87 9.5 10.3 0.16 11.8 1.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EDO16672.1 - 9.4 5.9 11.8 45 3.7 8.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain E1-E2_ATPase PF00122.15 EDO16673.1 - 1.2e-67 227.3 4.5 2.3e-67 226.3 3.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDO16673.1 - 2.6e-34 118.3 2.3 2.6e-34 118.3 1.6 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDO16673.1 - 1e-27 97.9 0.0 1.2e-23 84.6 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO16673.1 - 1.3e-17 63.4 0.0 2.8e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDO16673.1 - 3.6e-14 53.3 0.0 1.1e-13 51.7 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDO16673.1 - 6.7e-12 44.6 0.0 2.7e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDO16673.1 - 0.00016 21.3 0.4 0.003 17.1 0.5 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase tRNA-synt_2 PF00152.15 EDO16674.1 - 1.6e-87 293.4 0.3 2.5e-87 292.7 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDO16674.1 - 1.2e-12 47.5 0.7 5.7e-12 45.3 0.3 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDO16674.1 - 2.1e-07 30.4 0.0 0.0016 17.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Pkinase PF00069.20 EDO16675.1 - 6.2e-36 123.8 0.0 1.3e-35 122.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16675.1 - 2.9e-22 79.0 0.0 4.4e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO16675.1 - 0.00066 18.7 0.0 0.0016 17.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO16675.1 - 0.008 15.9 0.0 0.12 12.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Acyl_transf_3 PF01757.17 EDO16676.1 - 0.0061 15.4 0.5 0.0069 15.2 0.3 1.1 1 0 0 1 1 1 1 Acyltransferase family YchF-GTPase_C PF06071.8 EDO16678.1 - 9.1e-29 99.0 0.1 2.1e-28 97.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EDO16678.1 - 2.4e-15 56.5 0.1 7e-15 55.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EDO16678.1 - 5.9e-07 29.2 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EDO16678.1 - 0.0019 17.4 0.0 0.0039 16.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B OTU PF02338.14 EDO16679.1 - 3e-17 63.3 0.1 3e-17 63.3 0.0 2.9 2 1 1 3 3 3 1 OTU-like cysteine protease DUF3782 PF12644.2 EDO16679.1 - 0.084 12.6 0.2 0.084 12.6 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) IlvC PF01450.14 EDO16679.1 - 0.84 9.5 0.0 0.84 9.5 0.0 2.8 2 1 1 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain VitK2_biosynth PF02621.9 EDO16679.1 - 1.2 8.2 3.6 3.7 6.6 0.1 2.6 3 0 0 3 3 3 0 Menaquinone biosynthesis Flu_NS2 PF00601.14 EDO16679.1 - 7.9 6.7 8.2 17 5.6 0.6 3.2 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) CHCH PF06747.8 EDO16680.1 - 4.2e-08 32.8 4.0 7.8e-08 32.0 2.8 1.5 1 0 0 1 1 1 1 CHCH domain G-patch PF01585.18 EDO16681.1 - 2.7e-13 49.4 2.6 5.1e-13 48.5 1.8 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EDO16681.1 - 3.8e-06 26.6 0.2 9.9e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site APG17 PF04108.7 EDO16682.1 - 2.2e-121 405.5 15.2 2.5e-121 405.3 10.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Baculo_PEP_C PF04513.7 EDO16682.1 - 0.0014 18.4 0.2 0.0014 18.4 0.1 3.6 2 1 2 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EDO16682.1 - 0.052 13.8 5.7 4.2 7.7 0.1 4.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EDO16682.1 - 2.3 7.7 12.8 12 5.3 1.8 3.8 2 1 1 4 4 4 0 IncA protein DUF1664 PF07889.7 EDO16682.1 - 7.7 6.3 9.6 17 5.2 0.0 4.5 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) tRNA-synt_2b PF00587.20 EDO16683.1 - 1.4e-47 161.4 0.3 2.2e-47 160.8 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO16683.1 - 6.8e-15 54.7 0.0 1.3e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain PP-binding PF00550.20 EDO16684.1 - 8.1e-13 48.4 0.2 1e-12 48.0 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EDO16684.1 - 1.7e-07 31.1 0.5 2.2e-07 30.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EDO16684.1 - 0.002 18.2 0.1 0.0031 17.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Proteasom_Rpn13 PF04683.8 EDO16686.1 - 9e-21 73.7 0.3 1.6e-20 72.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome complex subunit Rpn13 ubiquitin receptor NOA36 PF06524.7 EDO16686.1 - 0.16 11.2 5.2 0.18 11.0 3.6 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 EDO16686.1 - 0.6 10.4 10.2 1 9.6 7.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 EDO16686.1 - 2.4 7.9 7.5 3.9 7.2 5.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Diphthamide_syn PF01866.12 EDO16687.1 - 2.7e-42 145.0 0.4 1.6e-21 76.8 0.0 2.9 2 2 1 3 3 3 2 Putative diphthamide synthesis protein EF-hand_1 PF00036.27 EDO16688.1 - 9.9e-25 83.9 12.6 1.1e-05 24.3 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EDO16688.1 - 4.9e-21 74.6 2.3 4e-11 42.8 0.5 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EDO16688.1 - 8.1e-20 68.8 4.6 0.00026 20.6 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EDO16688.1 - 1.2e-15 56.0 17.1 0.00018 20.6 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EDO16688.1 - 1.9e-12 46.6 12.6 0.0044 16.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 EDO16688.1 - 1.4e-06 27.9 10.7 0.021 14.5 0.2 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EDO16688.1 - 5.2e-06 26.4 0.0 0.031 14.2 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EDO16688.1 - 0.00018 21.3 0.0 0.93 9.4 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain DUF2205 PF10224.4 EDO16689.1 - 1.4e-08 34.1 5.2 1.5e-08 34.0 3.6 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Kinesin-relat_1 PF12711.2 EDO16689.1 - 0.026 14.9 5.8 0.26 11.6 0.1 2.0 1 1 1 2 2 2 0 Kinesin motor RBD-FIP PF09457.5 EDO16689.1 - 0.045 13.5 1.0 0.045 13.5 0.7 1.6 2 0 0 2 2 2 0 FIP domain EssA PF10661.4 EDO16689.1 - 0.057 13.0 1.0 0.066 12.8 0.7 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA UCR_14kD PF02271.11 EDO16689.1 - 0.087 12.5 0.2 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF837 PF05769.6 EDO16689.1 - 0.11 12.0 6.8 1.1 8.8 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF837) Macoilin PF09726.4 EDO16689.1 - 0.2 9.8 2.4 0.23 9.7 1.7 1.0 1 0 0 1 1 1 0 Transmembrane protein bZIP_1 PF00170.16 EDO16689.1 - 0.24 11.3 4.8 0.69 9.9 0.4 2.2 1 1 1 2 2 2 0 bZIP transcription factor TSC22 PF01166.13 EDO16689.1 - 0.99 9.4 5.9 0.84 9.6 1.0 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.10 EDO16689.1 - 2.2 7.8 5.6 2.3 7.7 0.7 2.0 1 1 1 2 2 2 0 Septum formation initiator Serinc PF03348.10 EDO16690.1 - 6.7e-154 512.7 17.1 7.9e-154 512.4 11.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Rad51 PF08423.6 EDO16691.1 - 6.2e-125 415.2 0.1 8.6e-125 414.7 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EDO16691.1 - 3.1e-10 39.7 0.0 4.6e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EDO16691.1 - 3.8e-09 36.0 0.1 5.2e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EDO16691.1 - 5.5e-08 32.2 0.0 1.2e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 KaiC HHH_5 PF14520.1 EDO16691.1 - 8e-05 22.7 0.1 0.0002 21.4 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain PAXNEB PF05625.6 EDO16691.1 - 0.0027 16.5 0.1 0.12 11.1 0.1 2.1 2 0 0 2 2 2 1 PAXNEB protein HTH_19 PF12844.2 EDO16691.1 - 0.013 15.5 0.1 4.1 7.5 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain RNA_pol_A_CTD PF03118.10 EDO16691.1 - 0.026 13.9 0.3 0.056 12.8 0.2 1.6 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain PH_4 PF15404.1 EDO16692.1 - 1.3e-60 204.1 0.1 1.3e-60 204.1 0.1 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.1 EDO16692.1 - 2.8e-21 74.7 0.0 9.2e-21 73.0 0.0 2.0 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 EDO16692.1 - 0.019 15.1 7.3 0.23 11.6 0.1 4.2 3 2 0 3 3 3 0 PH domain E1_dh PF00676.15 EDO16693.1 - 1.4e-120 401.6 0.0 1.7e-120 401.3 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EDO16693.1 - 0.021 13.7 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 EDO16693.1 - 0.097 13.3 2.7 1.1 9.9 0.1 2.9 2 2 0 2 2 2 0 KRTAP type 7 family COPI_assoc PF08507.5 EDO16694.1 - 9.7e-25 86.8 9.0 1.1e-24 86.6 6.3 1.0 1 0 0 1 1 1 1 COPI associated protein Sm_multidrug_ex PF06695.6 EDO16694.1 - 0.15 12.2 1.2 0.29 11.3 0.4 1.8 1 1 1 2 2 2 0 Putative small multi-drug export protein 14-3-3 PF00244.15 EDO16695.1 - 3.3e-105 350.4 3.9 3.8e-105 350.1 2.7 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF4085 PF13315.1 EDO16695.1 - 0.0097 15.3 0.5 0.0097 15.3 0.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4085) FlaF PF07309.6 EDO16695.1 - 0.069 13.0 0.2 0.2 11.5 0.2 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF tRNA-synt_2 PF00152.15 EDO16696.1 - 3e-76 256.3 0.0 4.5e-76 255.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDO16696.1 - 2.7e-06 27.1 0.0 5.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDO16696.1 - 9.8e-06 24.9 0.1 0.0014 17.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) RNase_HII PF01351.13 EDO16697.1 - 2.5e-62 210.0 0.0 3.2e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Tom7 PF08038.7 EDO16698.1 - 6.8e-22 76.6 0.4 8.3e-22 76.3 0.3 1.1 1 0 0 1 1 1 1 TOM7 family Ribosomal_L13 PF00572.13 EDO16699.1 - 4e-26 91.5 0.1 7.4e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 COX7B PF05392.6 EDO16700.1 - 0.028 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Fork_head PF00250.13 EDO16701.1 - 1.4e-34 117.9 2.7 1.5e-34 117.8 0.6 2.1 2 0 0 2 2 2 1 Fork head domain FHA PF00498.21 EDO16701.1 - 1.2e-10 41.2 0.1 3.7e-10 39.7 0.1 1.9 1 0 0 1 1 1 1 FHA domain MOR2-PAG1_N PF14222.1 EDO16702.1 - 3.3e-187 623.5 7.6 1.2e-186 621.6 5.3 2.1 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EDO16702.1 - 2.2e-97 325.9 2.3 2.2e-97 325.9 1.6 2.5 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EDO16702.1 - 9.4e-23 79.8 19.2 3.7e-10 38.1 0.7 3.6 2 2 1 3 3 3 3 Cell morphogenesis central region Ribosomal_L6 PF00347.18 EDO16703.1 - 2.5e-14 53.4 0.3 3e-14 53.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L6 UAF_Rrn10 PF05234.6 EDO16703.1 - 0.11 12.5 0.2 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 UAF complex subunit Rrn10 DUF1382 PF07131.6 EDO16703.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) SUN PF03856.8 EDO16704.1 - 3.3e-105 350.8 19.8 3.3e-105 350.8 13.7 1.9 2 1 1 3 3 1 1 Beta-glucosidase (SUN family) DUF4557 PF15101.1 EDO16704.1 - 0.017 14.9 8.7 0.026 14.3 6.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) SAPS PF04499.10 EDO16704.1 - 0.024 13.2 4.5 0.029 13.0 3.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3659 PF12396.3 EDO16704.1 - 0.085 12.5 0.1 4.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Spore_coat_CotO PF14153.1 EDO16704.1 - 0.22 10.9 10.9 0.32 10.4 7.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Gag_spuma PF03276.9 EDO16704.1 - 0.36 9.1 15.0 0.51 8.6 10.4 1.2 1 0 0 1 1 1 0 Spumavirus gag protein DUF853 PF05872.7 EDO16704.1 - 0.45 8.8 8.9 0.61 8.3 6.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Peptidase_S64 PF08192.6 EDO16704.1 - 0.48 8.7 12.8 0.59 8.4 8.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 DUF4603 PF15376.1 EDO16704.1 - 0.51 7.4 18.8 0.2 8.8 11.5 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4603) DUF572 PF04502.8 EDO16704.1 - 0.53 9.4 16.5 0.76 8.9 11.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAT1 PF09770.4 EDO16704.1 - 0.56 8.3 20.7 0.71 8.0 14.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.7 EDO16704.1 - 0.82 9.5 12.9 1.1 9.0 8.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 EDO16704.1 - 0.96 7.0 5.5 1.2 6.7 3.8 1.1 1 0 0 1 1 1 0 Ycf1 DUF2201_N PF13203.1 EDO16704.1 - 1 8.4 13.7 1.5 7.9 9.5 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain TFIIA PF03153.8 EDO16704.1 - 2.2 8.1 24.2 3.2 7.5 16.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.10 EDO16704.1 - 2.2 7.4 14.7 3.1 7.0 10.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Plasmodium_Vir PF05795.6 EDO16704.1 - 3 6.9 6.6 5.1 6.1 4.6 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF913 PF06025.7 EDO16704.1 - 3.3 6.3 10.6 4.4 5.9 7.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Macoilin PF09726.4 EDO16704.1 - 3.8 5.6 20.3 4.7 5.3 14.1 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4638 PF15472.1 EDO16704.1 - 4.6 6.7 8.0 7.3 6.1 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DHHW PF14286.1 EDO16704.1 - 5.2 6.2 12.9 10 5.3 9.0 1.5 1 0 0 1 1 1 0 DHHW protein Sporozoite_P67 PF05642.6 EDO16704.1 - 5.8 4.6 20.7 8.8 4.0 14.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Band_3_cyto PF07565.8 EDO16704.1 - 6.4 6.2 9.5 10 5.5 6.6 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hid1 PF12722.2 EDO16704.1 - 7.2 4.1 15.5 8.9 3.8 10.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.11 EDO16704.1 - 9.5 5.9 11.2 14 5.3 7.7 1.3 1 0 0 1 1 1 0 AUX/IAA family CPSF100_C PF13299.1 EDO16704.1 - 9.5 6.3 11.8 18 5.4 8.2 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal MRI PF15325.1 EDO16705.1 - 0.8 10.6 6.2 2.3 9.2 4.3 1.7 1 0 0 1 1 1 0 Modulator of retrovirus infection MFS_1 PF07690.11 EDO16706.1 - 5.1e-41 140.5 27.9 1.1e-39 136.1 10.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO16706.1 - 1.9e-12 46.4 14.9 1.9e-12 46.4 10.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EDO16706.1 - 0.00051 18.3 6.0 0.00089 17.5 4.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gly-zipper_Omp PF13488.1 EDO16706.1 - 0.099 12.2 2.7 0.22 11.1 1.9 1.5 1 0 0 1 1 1 0 Glycine zipper DnaJ PF00226.26 EDO16707.1 - 1.1e-26 92.2 0.6 1.8e-26 91.6 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDO16707.1 - 1.4e-19 69.7 0.3 3.9e-17 61.9 0.0 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDO16707.1 - 3.9e-13 49.2 19.4 4.5e-13 49.0 12.7 1.7 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 EDO16707.1 - 0.017 14.8 9.6 0.6 9.8 1.3 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Methyltransf_26 PF13659.1 EDO16708.1 - 2.3e-08 34.0 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO16708.1 - 2.3e-07 30.5 0.3 3.4e-07 29.9 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDO16708.1 - 6.9e-07 28.7 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EDO16708.1 - 0.00014 22.1 0.0 0.00037 20.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO16708.1 - 0.00016 22.1 0.0 0.00029 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EDO16708.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EDO16708.1 - 0.0047 16.0 0.1 0.0065 15.5 0.1 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase PPP5 PF08321.7 EDO16708.1 - 0.078 12.9 1.1 0.75 9.8 0.0 2.8 4 0 0 4 4 4 0 PPP5 TPR repeat region AviRa PF11599.3 EDO16708.1 - 0.084 11.8 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 RRNA methyltransferase AviRa TctC PF03401.9 EDO16708.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor Gcd10p PF04189.8 EDO16709.1 - 3.3e-106 354.7 6.5 4.1e-106 354.4 4.5 1.1 1 0 0 1 1 1 1 Gcd10p family YjfB_motility PF14070.1 EDO16709.1 - 5.7 6.8 8.0 6.5 6.6 1.8 2.4 2 0 0 2 2 2 0 Putative motility protein Nol1_Nop2_Fmu PF01189.12 EDO16710.1 - 1.3e-105 352.8 0.0 2e-105 352.2 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EDO16710.1 - 0.0006 19.8 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EDO16710.1 - 0.0014 18.2 0.0 0.0058 16.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain SR-25 PF10500.4 EDO16710.1 - 0.034 13.6 27.4 0.08 12.4 19.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bradykinin PF06753.7 EDO16710.1 - 0.59 9.6 2.1 1.2 8.6 1.4 1.5 1 0 0 1 1 1 0 Bradykinin Peptidase_S64 PF08192.6 EDO16710.1 - 2.3 6.4 17.1 3.5 5.8 11.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 Actin PF00022.14 EDO16711.1 - 3.2e-48 164.1 0.1 3.5e-27 94.8 0.0 2.3 2 0 0 2 2 2 2 Actin OmpH PF03938.9 EDO16711.1 - 3.5 7.5 29.6 3.4 7.6 6.3 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Y_phosphatase2 PF03162.8 EDO16713.1 - 3.3e-52 176.1 0.0 3.8e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EDO16713.1 - 5.8e-06 26.6 0.0 8.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Porin_3 PF01459.17 EDO16714.1 - 5.7e-58 196.3 11.7 6.4e-58 196.1 8.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin COG5 PF10392.4 EDO16715.1 - 1.5e-32 112.3 8.0 1.5e-32 112.3 5.5 3.1 2 1 1 3 3 3 1 Golgi transport complex subunit 5 NapD PF03927.8 EDO16715.1 - 0.12 12.1 0.6 2.8 7.8 0.1 2.6 2 1 0 2 2 2 0 NapD protein DUF2011 PF09428.5 EDO16716.1 - 2.7e-30 104.9 17.2 4.8e-30 104.1 11.9 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Flu_B_M2 PF04772.7 EDO16716.1 - 0.057 13.4 0.4 0.14 12.2 0.2 1.6 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) Sec23_trunk PF04811.10 EDO16717.1 - 5.3e-72 242.0 0.0 2.1e-71 240.1 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDO16717.1 - 2.1e-25 88.1 0.2 6.9e-25 86.4 0.1 2.0 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EDO16717.1 - 2.4e-18 65.3 4.9 4.7e-18 64.4 3.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EDO16717.1 - 9.8e-16 58.0 0.1 9.8e-16 58.0 0.1 2.3 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EDO16717.1 - 1.4e-08 34.3 0.0 4e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat IpaB_EvcA PF03278.8 EDO16717.1 - 1.5 8.0 6.9 0.35 10.0 1.6 2.2 2 0 0 2 2 2 0 IpaB/EvcA family Metallopep PF12044.3 EDO16718.1 - 1.1e-174 580.9 0.0 1.4e-174 580.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EDO16718.1 - 7.3e-05 22.6 0.0 0.00021 21.1 0.0 1.8 1 1 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 EDO16718.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EDO16718.1 - 0.028 14.9 0.1 0.075 13.5 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like 6PF2K PF01591.13 EDO16719.1 - 1.9e-77 259.2 0.1 1.9e-77 259.2 0.1 2.6 3 0 0 3 3 3 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDO16719.1 - 2.7e-32 112.0 0.3 1.4e-31 109.6 0.1 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EDO16719.1 - 2e-09 37.4 0.0 4.4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO16719.1 - 2.5e-09 37.9 1.6 6e-09 36.7 0.0 2.5 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO16719.1 - 0.00048 20.4 2.2 0.0026 18.0 0.0 3.1 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EDO16719.1 - 0.0016 18.0 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 EDO16719.1 - 0.002 17.3 0.0 0.0043 16.2 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EDO16719.1 - 0.051 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Pox_A28 PF04584.9 EDO16719.1 - 0.22 11.3 0.0 0.22 11.3 0.0 2.5 3 0 0 3 3 3 0 Poxvirus A28 family DUF2722 PF10846.3 EDO16720.1 - 9.2e-74 248.9 28.5 1.4e-36 126.4 13.8 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2722) SHQ1 PF04925.10 EDO16721.1 - 2.4e-77 258.6 1.6 3.9e-77 257.9 1.1 1.3 1 0 0 1 1 1 1 SHQ1 protein Diphthamide_syn PF01866.12 EDO16722.1 - 5.8e-115 383.7 0.1 6.9e-115 383.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Pro_CA PF00484.14 EDO16724.1 - 9.9e-35 119.7 0.1 1.4e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase XhlA PF10779.4 EDO16724.1 - 0.037 13.9 1.8 0.087 12.7 1.3 1.6 1 0 0 1 1 1 0 Haemolysin XhlA Imm-NTF2 PF15655.1 EDO16724.1 - 0.048 14.1 0.5 0.92 9.9 0.2 2.2 2 0 0 2 2 2 0 NTF2 fold immunity protein Complex1_LYR_2 PF13233.1 EDO16725.1 - 5.2e-20 71.8 1.9 7.9e-20 71.2 1.3 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF1192 PF06698.6 EDO16725.1 - 0.027 14.2 0.2 0.87 9.4 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) YhfZ_C PF14503.1 EDO16725.1 - 0.043 13.1 5.0 0.023 14.0 1.0 1.9 1 1 1 2 2 2 0 YhfZ C-terminal domain Med4 PF10018.4 EDO16725.1 - 0.48 9.7 11.0 0.057 12.8 2.2 2.1 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 RNA_pol_Rpb1_5 PF04998.12 EDO16725.1 - 3.4 6.8 6.1 3.9 6.6 4.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF2431 PF10354.4 EDO16726.1 - 3.5e-59 199.4 0.3 9.2e-59 198.1 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Band_3_cyto PF07565.8 EDO16726.1 - 0.41 10.1 3.2 0.13 11.7 0.2 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain PIG-H PF10181.4 EDO16727.1 - 1e-20 73.0 0.7 2e-20 72.1 0.5 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Myb_DNA-binding PF00249.26 EDO16728.1 - 5.7e-10 39.0 0.2 1.5e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO16728.1 - 0.015 15.3 0.1 0.015 15.3 0.1 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain Viral_P18 PF04521.8 EDO16728.1 - 0.028 13.8 2.3 4.7 6.6 0.8 3.0 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein IncA PF04156.9 EDO16728.1 - 0.029 13.9 0.7 0.029 13.9 0.5 3.5 3 1 0 3 3 3 0 IncA protein WD40 PF00400.27 EDO16729.1 - 2.2e-10 40.0 0.5 2.4e-05 24.0 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Pkinase PF00069.20 EDO16730.1 - 3.6e-39 134.5 1.7 7.3e-39 133.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16730.1 - 2e-28 99.2 0.9 3.2e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO16730.1 - 7.7e-05 21.7 0.0 0.00017 20.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like BAF1_ABF1 PF04684.8 EDO16730.1 - 0.041 12.7 23.1 0.08 11.7 16.0 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2968 PF11180.3 EDO16730.1 - 2.3 7.5 19.4 4.7 6.5 13.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DivIC PF04977.10 EDO16730.1 - 3.2 7.3 11.2 10 5.7 7.8 1.8 1 0 0 1 1 1 0 Septum formation initiator CPSF100_C PF13299.1 EDO16730.1 - 4.2 7.5 17.7 0.82 9.8 0.4 3.4 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Arb2 PF09757.4 EDO16731.1 - 2.8e-23 82.2 0.1 4.4e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Arb2 domain V-set_CD47 PF08204.6 EDO16731.1 - 0.01 15.5 2.6 0.53 10.0 0.1 2.2 2 0 0 2 2 2 0 CD47 immunoglobulin-like domain Hist_deacetyl PF00850.14 EDO16732.1 - 4.1e-73 246.3 0.0 4.9e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Nol1_Nop2_Fmu PF01189.12 EDO16733.1 - 2.3e-18 66.5 0.0 1.4e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_15 PF09445.5 EDO16733.1 - 0.00089 18.8 0.4 0.0068 15.9 0.0 2.2 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EDO16733.1 - 0.002 18.1 0.0 0.0034 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain zf-P11 PF03854.9 EDO16733.1 - 0.077 12.4 0.2 0.2 11.1 0.2 1.6 1 0 0 1 1 1 0 P-11 zinc finger FtsJ PF01728.14 EDO16733.1 - 0.092 12.7 0.0 0.77 9.7 0.0 2.2 1 1 1 2 2 2 0 FtsJ-like methyltransferase Met_10 PF02475.11 EDO16733.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Iso_dh PF00180.15 EDO16734.1 - 4.5e-106 354.7 0.0 5.5e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Dicty_CAD PF05720.7 EDO16734.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Cell-cell adhesion domain MRP-S25 PF13741.1 EDO16735.1 - 1e-93 313.0 2.2 1.2e-93 312.8 1.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EDO16735.1 - 0.00017 21.5 0.0 0.0079 16.0 0.0 2.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein S23 DUF1242 PF06842.7 EDO16736.1 - 7e-18 63.8 0.2 9.1e-18 63.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) ICE2 PF08426.5 EDO16737.1 - 1.7e-164 547.3 28.7 1.9e-164 547.1 19.9 1.0 1 0 0 1 1 1 1 ICE2 Cyclin_N PF00134.18 EDO16738.1 - 1.1e-16 60.6 0.4 1e-15 57.4 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EDO16738.1 - 0.004 17.0 3.3 0.12 12.3 0.0 3.3 3 0 0 3 3 3 1 Cyclin, C-terminal domain Aa_trans PF01490.13 EDO16739.1 - 3.6e-106 355.0 26.4 4.5e-106 354.7 18.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PepSY_TM_2 PF13703.1 EDO16739.1 - 0.015 15.4 1.1 0.015 15.4 0.7 3.7 4 0 0 4 4 4 0 PepSY-associated TM helix Y_phosphatase2 PF03162.8 EDO16740.1 - 5e-65 217.8 0.0 6.7e-65 217.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EDO16740.1 - 2.4e-07 31.1 0.0 5.8e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EDO16740.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EDO16740.1 - 0.0021 17.4 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Histone PF00125.19 EDO16741.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDO16741.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDO16741.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EDO16741.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EDO16742.1 - 2.5e-15 56.3 0.2 3.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDO16742.1 - 3.2e-05 23.8 0.1 5.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EDO16742.1 - 4.4e-05 23.3 0.2 6.2e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EDO16742.1 - 5e-05 23.3 0.1 7e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EDO16742.1 - 0.0012 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EDO16742.1 - 0.0042 16.7 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EDO16742.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 EDO16742.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Met_10 PF02475.11 EDO16743.1 - 5.2e-12 45.7 0.0 1.7e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EDO16743.1 - 1.2e-05 24.7 0.0 2.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 EDO16743.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EDO16743.1 - 0.0029 17.6 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EDO16743.1 - 0.042 12.5 0.0 0.066 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase zf-H2C2_2 PF13465.1 EDO16744.1 - 6.9e-14 51.3 14.8 1.1e-07 31.7 1.3 4.0 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EDO16744.1 - 1.2e-12 47.3 13.9 6.8e-07 29.2 1.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO16744.1 - 1.6e-11 43.6 10.6 0.00016 21.7 0.8 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 EDO16744.1 - 8.4e-05 22.6 3.8 0.00064 19.8 0.2 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDO16744.1 - 0.00026 21.0 15.1 0.0038 17.3 0.2 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EDO16744.1 - 0.00057 19.6 6.7 1.8 8.5 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_ribbon_recom PF13408.1 EDO16744.1 - 0.0016 18.6 2.6 0.0016 18.6 1.8 2.3 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.2 EDO16744.1 - 0.1 12.4 2.8 0.23 11.3 2.0 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EDO16744.1 - 0.28 11.1 2.5 10 6.1 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain PHD_3 PF13922.1 EDO16744.1 - 9.1 6.6 10.7 71 3.7 7.4 2.6 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx Bac_surface_Ag PF01103.18 EDO16745.1 - 3.8e-44 151.4 11.4 5.1e-44 151.0 7.9 1.2 1 0 0 1 1 1 1 Surface antigen DUF3984 PF13136.1 EDO16745.1 - 0.094 11.9 0.2 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DFP PF04127.10 EDO16746.1 - 1.5e-14 54.0 0.0 7.2e-06 25.7 0.0 3.0 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein UCH PF00443.24 EDO16747.1 - 5.8e-48 163.3 1.4 9.6e-48 162.6 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO16747.1 - 4.4e-13 49.3 2.2 1.1e-07 31.6 0.3 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF2570 PF10828.3 EDO16748.1 - 0.0081 15.7 3.0 0.75 9.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2570) FixG_C PF11614.3 EDO16748.1 - 0.039 14.0 0.9 0.056 13.5 0.6 1.2 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase OppC_N PF12911.2 EDO16748.1 - 0.061 12.6 0.1 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DNA_pol_B_2 PF03175.8 EDO16748.1 - 0.089 11.4 4.0 0.1 11.2 2.8 1.0 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral ABC2_membrane_3 PF12698.2 EDO16748.1 - 0.16 10.9 1.3 0.19 10.7 0.9 1.2 1 1 0 1 1 1 0 ABC-2 family transporter protein TFIIS_M PF07500.9 EDO16748.1 - 0.54 10.3 9.6 17 5.5 6.6 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain PI31_Prot_N PF11566.3 EDO16748.1 - 1.7 8.2 7.0 5.1 6.6 4.9 1.7 1 1 0 1 1 1 0 PI31 proteasome regulator N-terminal Colicin-DNase PF12639.2 EDO16748.1 - 6.4 7.0 7.4 0.92 9.7 0.8 2.0 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Picorna_P3A PF06363.6 EDO16750.1 - 0.054 13.4 0.1 0.15 12.0 0.0 1.7 1 1 0 1 1 1 0 Picornaviridae P3A protein DnaJ PF00226.26 EDO16754.1 - 9.5e-26 89.3 0.7 1.6e-25 88.5 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain SPOB_a PF14689.1 EDO16754.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain DUF633 PF04816.7 EDO16754.1 - 0.086 12.1 0.2 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) DUF2489 PF10675.4 EDO16754.1 - 0.21 11.2 2.0 0.49 10.0 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2489) Nse4_C PF08743.5 EDO16755.1 - 2.6e-22 78.6 0.4 1.1e-21 76.6 0.3 2.2 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EDO16755.1 - 3.3e-14 52.4 0.4 7.3e-14 51.3 0.3 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF1712 PF08217.6 EDO16756.1 - 1.3e-221 737.0 38.1 1.5e-221 736.8 26.4 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) AA_permease PF00324.16 EDO16757.1 - 4.5e-125 417.7 28.9 5.1e-125 417.5 20.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO16757.1 - 9.2e-24 83.7 33.3 1.2e-23 83.3 23.1 1.1 1 0 0 1 1 1 1 Amino acid permease PRMT5 PF05185.11 EDO16758.1 - 5.1e-153 510.1 3.5 7e-153 509.7 2.5 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 EDO16758.1 - 0.055 13.0 0.1 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PI3_PI4_kinase PF00454.22 EDO16759.1 - 5.8e-48 163.4 1.7 1.2e-46 159.0 0.1 2.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 EDO16759.1 - 5.1e-34 116.4 2.9 3.3e-33 113.8 0.9 3.5 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 EDO16759.1 - 1e-14 53.6 0.2 2.3e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 EDO16759.1 - 0.00055 19.5 2.8 0.7 9.5 0.1 3.8 2 1 2 4 4 4 2 TPR repeat TPR_21 PF09976.4 EDO16759.1 - 0.79 9.6 0.0 2 8.3 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Vac14_Fab1_bd PF12755.2 EDO16759.1 - 0.89 9.9 6.2 26 5.2 0.0 5.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Pyridox_oxase_2 PF12766.2 EDO16761.1 - 6.4e-32 109.8 0.0 1.3e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase BRCT PF00533.21 EDO16762.1 - 3.8e-08 33.3 0.0 1.3e-07 31.7 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EDO16762.1 - 0.0008 19.2 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 EDO16762.1 - 0.0031 17.6 1.4 0.0055 16.8 0.0 2.1 2 0 0 2 2 2 1 Fibronectin type III domain Transcrip_reg PF01709.15 EDO16763.1 - 4.7e-72 241.8 4.6 5.4e-72 241.6 3.2 1.0 1 0 0 1 1 1 1 Transcriptional regulator SF3b1 PF08920.5 EDO16763.1 - 0.025 14.5 1.7 0.052 13.5 0.1 2.2 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 CENP-B_N PF04218.8 EDO16763.1 - 0.033 13.5 0.0 0.08 12.3 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain Thioredoxin_2 PF13098.1 EDO16763.1 - 0.096 12.8 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain SapB_1 PF05184.10 EDO16763.1 - 4.6 7.1 5.1 0.63 9.9 0.2 2.2 3 0 0 3 3 3 0 Saposin-like type B, region 1 Mid2 PF04478.7 EDO16764.1 - 6.2e-48 162.1 0.3 6.2e-48 162.1 0.2 2.7 3 0 0 3 3 3 1 Mid2 like cell wall stress sensor ADH_N PF08240.7 EDO16765.1 - 4.4e-24 84.3 5.6 8.1e-24 83.4 3.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO16765.1 - 6e-14 51.6 0.0 9.6e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDO16765.1 - 2.4e-06 26.8 0.1 4.3e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EDO16765.1 - 0.066 13.2 0.0 0.09 12.7 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_2 PF03446.10 EDO16765.1 - 0.085 12.6 0.1 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF364 PF04016.7 EDO16765.1 - 0.093 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF364) Thg1 PF04446.7 EDO16766.1 - 9.2e-47 158.0 1.1 1.3e-46 157.6 0.8 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 EDO16766.1 - 2.3e-37 127.3 1.0 4.9e-37 126.2 0.5 1.7 2 0 0 2 2 2 1 Thg1 C terminal domain Ribosomal_S25 PF03297.10 EDO16767.1 - 9.1e-44 147.8 6.8 1e-43 147.6 4.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 EDO16767.1 - 0.00067 19.3 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.6 EDO16767.1 - 0.021 14.1 0.3 0.03 13.6 0.2 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_DeoR PF08220.7 EDO16767.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TAF4 PF05236.9 EDO16767.1 - 0.078 12.2 1.1 0.11 11.8 0.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF747 PF05346.6 EDO16768.1 - 5.9e-95 318.1 19.3 8.2e-95 317.6 13.4 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Mito_fiss_reg PF05308.6 EDO16768.1 - 0.062 12.6 0.3 0.1 11.9 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator COX15-CtaA PF02628.10 EDO16769.1 - 1.3e-98 329.5 5.8 1.6e-98 329.3 4.0 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Bax1-I PF01027.15 EDO16769.1 - 0.0037 16.9 0.4 0.0037 16.9 0.3 3.4 3 1 1 4 4 4 1 Inhibitor of apoptosis-promoting Bax1 Asp_protease PF09668.5 EDO16770.1 - 1.4e-51 173.2 0.1 2.3e-51 172.5 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EDO16770.1 - 7.3e-10 39.2 0.1 1.7e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EDO16770.1 - 3.8e-09 36.3 0.1 9.5e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA PF00627.26 EDO16770.1 - 2.4e-08 33.5 0.0 7.6e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain gag-asp_proteas PF13975.1 EDO16770.1 - 1.4e-05 24.8 0.0 3.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EDO16770.1 - 2.4e-05 24.3 0.0 4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.3 EDO16770.1 - 0.02 15.1 0.1 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 DUF1335 PF07056.6 EDO16770.1 - 0.1 12.3 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1335) Con-6 PF10346.4 EDO16770.1 - 0.32 10.4 1.5 0.97 8.8 1.1 1.8 1 0 0 1 1 1 0 Conidiation protein 6 Pex14_N PF04695.8 EDO16770.1 - 1 9.4 4.9 0.31 11.0 0.9 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Y_phosphatase2 PF03162.8 EDO16771.1 - 3.4e-46 156.6 1.2 4.3e-46 156.2 0.8 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Phage_RpbA PF10789.4 EDO16772.1 - 0.061 13.1 0.3 0.074 12.9 0.2 1.1 1 0 0 1 1 1 0 Phage RNA polymerase binding, RpbA DUF3327 PF11806.3 EDO16772.1 - 0.11 12.8 0.1 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3327) LSM PF01423.17 EDO16773.1 - 1.7e-18 65.9 0.2 1.9e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain BPL_C PF02237.12 EDO16773.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain TetR_C_8 PF14278.1 EDO16774.1 - 0.16 12.3 4.8 14 6.1 1.2 3.0 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region Fasciclin PF02469.17 EDO16775.1 - 0.0018 18.2 0.0 0.0036 17.3 0.0 1.5 1 1 0 1 1 1 1 Fasciclin domain DUF1676 PF07898.8 EDO16775.1 - 0.033 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) HLH PF00010.21 EDO16776.1 - 7.1e-18 64.0 1.1 1.5e-17 63.0 0.8 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain XPG_N PF00752.12 EDO16778.1 - 1.1e-28 99.4 0.0 3.3e-28 97.9 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EDO16778.1 - 1.8e-22 79.2 0.0 4.6e-22 77.8 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EDO16778.1 - 0.0029 17.8 0.0 0.008 16.3 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold XPG_I_2 PF12813.2 EDO16778.1 - 0.032 13.7 0.1 0.06 12.8 0.1 1.4 1 0 0 1 1 1 0 XPG domain containing HHH_2 PF12826.2 EDO16778.1 - 0.038 13.8 0.0 1.2 9.1 0.0 3.0 4 0 0 4 4 4 0 Helix-hairpin-helix motif Ank_2 PF12796.2 EDO16779.1 - 1.6e-31 108.4 0.1 3.5e-09 36.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDO16779.1 - 1.7e-30 103.3 1.4 5.6e-08 32.2 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EDO16779.1 - 8.6e-30 102.0 1.4 4e-09 36.4 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EDO16779.1 - 9.1e-24 83.3 1.4 5.2e-07 30.0 0.0 5.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO16779.1 - 1.4e-22 77.4 1.1 0.00032 20.6 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat zf-DHHC PF01529.15 EDO16779.1 - 1.7e-22 79.6 2.3 1.7e-22 79.6 1.6 2.3 1 1 2 3 3 3 1 DHHC palmitoyltransferase UNC45-central PF11701.3 EDO16780.1 - 4.2e-30 104.4 2.7 4.2e-30 104.4 1.9 2.8 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Pex2_Pex12 PF04757.9 EDO16781.1 - 4.7e-35 121.0 5.6 8.7e-35 120.1 3.9 1.4 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EDO16781.1 - 2.6e-09 36.7 12.1 5e-09 35.8 8.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDO16781.1 - 4e-08 33.1 13.6 8e-08 32.1 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO16781.1 - 6.8e-08 32.0 12.0 1.3e-07 31.1 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO16781.1 - 1.8e-07 30.7 13.6 3e-07 30.0 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO16781.1 - 2e-06 27.4 9.2 4.3e-06 26.3 6.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EDO16781.1 - 0.00011 22.0 13.1 0.00025 20.8 9.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EDO16781.1 - 0.0015 18.5 11.2 0.0067 16.5 7.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EDO16781.1 - 0.0058 16.3 7.6 0.031 13.9 5.2 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EDO16781.1 - 0.25 11.2 8.9 0.1 12.4 4.4 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EDO16781.1 - 0.74 9.6 8.3 1.6 8.5 5.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EDO16782.1 - 3.8e-06 26.4 7.7 3.8e-06 26.4 5.3 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Strabismus PF06638.6 EDO16782.1 - 0.0094 14.3 0.1 0.015 13.5 0.0 1.3 1 0 0 1 1 1 1 Strabismus protein zf-C3HC4 PF00097.20 EDO16782.1 - 0.016 14.8 11.3 0.016 14.8 7.8 3.8 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 EDO16782.1 - 1.9 8.7 20.8 0.47 10.6 0.6 4.8 4 1 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Syntaxin_2 PF14523.1 EDO16783.1 - 6.5e-19 67.8 3.5 6.5e-19 67.8 2.4 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EDO16783.1 - 3.4e-18 65.0 2.0 3.4e-18 65.0 1.4 3.1 4 1 0 4 4 4 1 SNARE domain Use1 PF09753.4 EDO16783.1 - 0.0051 16.2 4.4 0.0067 15.9 3.1 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 BLOC1_2 PF10046.4 EDO16783.1 - 0.022 14.8 11.1 3.4 7.8 1.9 3.7 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Viral_cys_rich PF08008.7 EDO16783.1 - 0.048 13.2 0.7 4.9 6.7 0.1 2.4 2 0 0 2 2 2 0 Viral cysteine rich ABC2_membrane_3 PF12698.2 EDO16783.1 - 0.11 11.4 2.6 0.15 11.0 1.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein MCPsignal PF00015.16 EDO16783.1 - 0.62 9.5 8.5 0.19 11.2 0.5 2.6 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ING PF12998.2 EDO16783.1 - 0.96 9.7 6.6 5.4 7.3 2.3 2.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Med28 PF11594.3 EDO16783.1 - 2.7 8.2 7.7 2.2 8.5 0.2 2.7 2 1 0 2 2 2 0 Mediator complex subunit 28 DUF1664 PF07889.7 EDO16783.1 - 5.4 6.8 9.2 6.7 6.5 0.3 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) WD40 PF00400.27 EDO16784.1 - 2e-53 176.4 23.1 1.2e-11 44.0 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EDO16784.1 - 0.0015 18.2 3.8 2.6 7.7 0.1 4.0 3 1 1 4 4 4 2 Transcription factor IIIC subunit delta N-term Coatomer_WDAD PF04053.9 EDO16784.1 - 0.04 12.7 7.8 0.28 9.9 0.9 2.7 2 1 1 3 3 3 0 Coatomer WD associated region IKI3 PF04762.7 EDO16784.1 - 0.13 10.0 4.3 0.88 7.2 0.9 2.4 2 0 0 2 2 2 0 IKI3 family BING4CT PF08149.6 EDO16784.1 - 0.16 11.5 0.0 17 5.0 0.0 2.4 2 0 0 2 2 2 0 BING4CT (NUC141) domain FAD_binding_6 PF00970.19 EDO16785.1 - 5e-07 29.7 0.0 2e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EDO16785.1 - 0.053 14.0 0.0 0.13 12.8 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain tRNA-synt_1b PF00579.20 EDO16786.1 - 7.1e-75 251.8 0.1 9.4e-75 251.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Hira PF07569.6 EDO16787.1 - 6.6e-88 293.5 0.1 6.6e-88 293.5 0.1 3.2 5 0 0 5 5 5 2 TUP1-like enhancer of split CK_II_beta PF01214.13 EDO16788.1 - 3.4e-72 241.8 0.1 4e-72 241.5 0.1 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF713 PF05218.9 EDO16788.1 - 0.025 14.3 0.2 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF713) E1-E2_ATPase PF00122.15 EDO16789.1 - 4.6e-50 169.8 0.1 1e-49 168.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDO16789.1 - 2.5e-33 116.3 0.0 4.1e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EDO16789.1 - 1.8e-25 88.8 9.4 4.5e-14 52.3 1.0 3.4 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.2 EDO16789.1 - 4.7e-12 46.4 0.8 1.2e-11 45.1 0.2 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDO16789.1 - 2.9e-06 27.0 1.5 0.00013 21.6 0.0 3.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4358 PF14270.1 EDO16789.1 - 0.024 14.4 0.0 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Lactamase_B PF00753.22 EDO16790.1 - 2.2e-22 79.6 0.1 3.8e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EDO16790.1 - 6.8e-06 25.7 0.1 1.5e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EDO16790.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain CUE PF02845.11 EDO16791.1 - 9.2e-12 44.2 0.0 2.2e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 CUE domain BTB_2 PF02214.17 EDO16792.1 - 0.0056 16.8 0.1 0.021 15.0 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain COX5A PF02284.11 EDO16792.1 - 0.061 13.2 0.1 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Pmp3 PF01679.12 EDO16794.1 - 2.9e-17 62.0 8.3 3.5e-17 61.8 5.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1212 PF06738.7 EDO16794.1 - 0.11 11.9 1.0 0.13 11.7 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) DUF3021 PF11457.3 EDO16794.1 - 1.2 9.0 3.9 1.3 8.9 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) PsbH PF00737.15 EDO16794.1 - 2 8.0 7.1 0.9 9.1 0.8 2.4 1 1 2 3 3 3 0 Photosystem II 10 kDa phosphoprotein DUF3533 PF12051.3 EDO16795.1 - 4.4e-133 443.7 18.1 5.2e-133 443.4 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.7 EDO16795.1 - 0.28 10.8 0.0 0.28 10.8 0.0 2.2 3 0 0 3 3 3 0 CDR ABC transporter DUF3533 PF12051.3 EDO16796.1 - 8e-133 442.8 21.3 1.1e-132 442.3 14.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) RTA1 PF04479.8 EDO16798.1 - 2.5e-72 243.0 8.9 3.3e-72 242.6 6.2 1.2 1 0 0 1 1 1 1 RTA1 like protein 2TM PF13239.1 EDO16798.1 - 4.5 7.4 9.8 0.42 10.7 1.8 2.8 2 1 0 2 2 2 0 2TM domain TP_methylase PF00590.15 EDO16799.1 - 5.1e-37 127.6 0.0 6.8e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.1 EDO16799.1 - 0.00032 19.6 0.1 0.00076 18.4 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.1 EDO16799.1 - 0.013 15.7 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EDO16799.1 - 0.058 12.7 0.0 14 5.0 0.0 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Ribosomal_S4e PF00900.15 EDO16800.1 - 6.5e-34 115.4 2.4 9.4e-33 111.7 0.6 2.2 2 0 0 2 2 2 1 Ribosomal family S4e KOW PF00467.24 EDO16800.1 - 7.4e-06 25.4 1.5 7.4e-06 25.4 1.0 3.9 4 1 0 4 4 4 1 KOW motif S4 PF01479.20 EDO16800.1 - 0.00015 21.1 0.0 0.00039 19.7 0.0 1.8 1 0 0 1 1 1 1 S4 domain TrmE_N PF10396.4 EDO16801.1 - 7.2e-36 122.6 0.0 1.5e-35 121.5 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EDO16801.1 - 9.6e-21 73.9 2.5 2.4e-20 72.6 0.6 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 EDO16801.1 - 3.2e-16 59.4 0.0 1.1e-15 57.7 0.0 2.0 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 EDO16801.1 - 1.5e-10 40.6 2.0 2.9e-10 39.6 1.4 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EDO16801.1 - 2.2e-05 23.9 0.6 0.00079 18.9 0.1 2.4 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EDO16801.1 - 0.00033 21.1 0.2 0.0019 18.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EDO16801.1 - 0.00035 20.4 4.8 0.0052 16.6 0.1 3.1 3 0 0 3 3 3 1 Dynamin family Ras PF00071.17 EDO16801.1 - 0.0015 17.9 0.6 0.0079 15.5 0.1 2.5 2 1 0 2 2 2 1 Ras family Arf PF00025.16 EDO16801.1 - 0.0026 17.0 2.0 0.045 13.0 1.4 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.11 EDO16801.1 - 0.052 12.7 0.1 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDO16801.1 - 0.1 12.7 0.9 0.94 9.6 0.4 2.5 2 1 0 2 2 2 0 AAA domain BCAS2 PF05700.6 EDO16802.1 - 0.052 13.0 0.5 0.052 12.9 0.4 1.3 1 1 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) YgaB PF14182.1 EDO16802.1 - 0.075 13.2 1.0 3.3 8.0 0.1 2.4 1 1 0 2 2 2 0 YgaB-like protein BLOC1_2 PF10046.4 EDO16802.1 - 0.29 11.3 2.4 0.79 9.8 1.6 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2347 PF09804.4 EDO16803.1 - 2.2e-86 289.6 0.4 3.1e-86 289.1 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EDO16803.1 - 6.6e-13 49.1 0.3 7e-06 26.2 0.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) Avl9 PF09794.4 EDO16803.1 - 2.7e-09 35.9 0.7 4.6e-07 28.6 0.0 2.9 2 1 0 3 3 3 2 Transport protein Avl9 SPA PF08616.5 EDO16803.1 - 0.00076 19.1 0.2 0.0023 17.6 0.1 1.9 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 EDO16803.1 - 0.0034 17.3 0.2 0.024 14.6 0.0 2.5 2 1 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Glyco_hydro_76 PF03663.9 EDO16804.1 - 2.6e-151 504.2 26.5 3.4e-151 503.8 18.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 UQ_con PF00179.21 EDO16805.1 - 1.7e-48 163.5 0.0 2e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDO16805.1 - 0.054 13.3 0.5 0.088 12.7 0.3 1.6 1 1 0 1 1 1 0 RWD domain Copper-fist PF00649.13 EDO16806.1 - 1.2e-20 72.3 3.3 1.2e-20 72.3 2.3 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain DUF1517 PF07466.6 EDO16806.1 - 0.035 13.1 4.7 0.062 12.2 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DNA_primase_lrg PF04104.9 EDO16807.1 - 1e-84 283.9 1.5 1.5e-84 283.3 1.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Hid1 PF12722.2 EDO16808.1 - 0.35 8.4 29.7 0.061 10.9 14.5 2.1 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein p450 PF00067.17 EDO16809.1 - 1.9e-53 181.6 0.0 2.5e-53 181.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Snf7 PF03357.16 EDO16811.1 - 1.1e-32 112.8 18.9 1.1e-32 112.8 13.1 1.5 1 1 0 1 1 1 1 Snf7 PAS_7 PF12860.2 EDO16811.1 - 0.0022 17.9 4.4 0.24 11.4 0.0 2.8 2 1 2 4 4 4 2 PAS fold Eno-Rase_FAD_bd PF07055.7 EDO16811.1 - 0.14 12.1 2.5 0.3 11.0 1.4 1.9 1 1 0 1 1 1 0 Enoyl reductase FAD binding domain DUF489 PF04356.7 EDO16811.1 - 0.96 9.0 8.6 1.8 8.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF489) PhoU PF01895.14 EDO16811.1 - 1.5 9.2 13.3 0.06 13.7 1.6 3.0 2 2 1 3 3 3 0 PhoU domain Adap_comp_sub PF00928.16 EDO16812.1 - 2.9e-62 210.1 5.3 3.8e-62 209.7 3.6 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pterin_4a PF01329.14 EDO16813.1 - 3e-26 90.9 0.0 3.5e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Tox-MPTase3 PF15639.1 EDO16813.1 - 0.042 13.5 0.0 0.054 13.2 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase toxin 3 Lung_7-TM_R PF06814.8 EDO16814.1 - 1.1e-81 274.0 25.2 1.4e-81 273.6 17.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Actin PF00022.14 EDO16815.1 - 4.9e-92 308.3 0.0 1e-91 307.2 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EDO16815.1 - 3.9e-05 22.4 0.0 0.046 12.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein TFIIS_C PF01096.13 EDO16816.1 - 1.1e-16 60.1 1.6 1.1e-16 60.1 1.1 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EDO16816.1 - 4e-12 45.6 8.6 1.9e-10 40.2 0.3 3.0 2 1 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EDO16816.1 - 0.0011 18.7 4.3 0.18 11.6 1.7 2.7 2 1 0 2 2 2 1 Transposase zinc-ribbon domain DZR PF12773.2 EDO16816.1 - 0.0012 18.6 7.7 0.18 11.6 0.2 3.0 2 1 1 3 3 3 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EDO16816.1 - 0.0014 17.7 9.9 1.3 8.3 0.2 4.2 4 0 0 4 4 4 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EDO16816.1 - 0.0025 17.4 8.4 4 7.2 0.5 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EDO16816.1 - 0.0027 17.2 8.6 3.5 7.2 0.5 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.1 EDO16816.1 - 0.0056 16.9 6.5 0.012 15.8 0.3 2.8 2 1 1 3 3 3 1 Restriction alleviation protein Lar zf-DNA_Pol PF08996.5 EDO16816.1 - 0.011 15.0 4.1 0.082 12.2 0.5 2.1 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-C3HC4_3 PF13920.1 EDO16816.1 - 0.013 15.1 2.1 3.6 7.3 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CpXC PF14353.1 EDO16816.1 - 0.028 14.3 4.7 0.68 9.8 0.1 3.0 2 1 1 3 3 3 0 CpXC protein zf-CSL PF05207.8 EDO16816.1 - 0.03 13.8 0.2 0.03 13.8 0.1 2.2 2 1 1 3 3 2 0 CSL zinc finger Terminase_GpA PF05876.7 EDO16816.1 - 0.033 12.5 1.7 0.032 12.6 0.5 1.4 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) DUF2072 PF09845.4 EDO16816.1 - 0.037 13.9 0.1 0.037 13.9 0.1 2.4 1 1 1 3 3 3 0 Zn-ribbon containing protein (DUF2072) Stc1 PF12898.2 EDO16816.1 - 0.044 13.8 5.0 0.055 13.5 0.1 2.2 1 1 1 2 2 2 0 Stc1 domain Zn-ribbon_8 PF09723.5 EDO16816.1 - 0.059 13.3 9.0 1.7 8.6 0.1 3.6 3 1 0 3 3 3 0 Zinc ribbon domain SprT-like PF10263.4 EDO16816.1 - 0.081 12.5 0.8 5.2 6.7 0.1 2.1 2 0 0 2 2 2 0 SprT-like family C1_1 PF00130.17 EDO16816.1 - 0.089 12.5 2.5 0.97 9.2 0.1 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rubredoxin PF00301.15 EDO16816.1 - 0.13 12.1 5.0 23 4.9 0.0 3.4 3 0 0 3 3 3 0 Rubredoxin Nop10p PF04135.7 EDO16816.1 - 0.15 11.8 1.0 0.29 10.9 0.2 2.0 2 0 0 2 2 1 0 Nucleolar RNA-binding protein, Nop10p family zf-TFIIB PF13453.1 EDO16816.1 - 0.19 10.9 6.5 0.091 11.9 1.2 2.4 2 1 0 2 2 2 0 Transcription factor zinc-finger DUF2082 PF09855.4 EDO16816.1 - 0.35 10.7 0.2 0.35 10.7 0.2 3.0 3 1 1 4 4 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-C2H2_6 PF13912.1 EDO16816.1 - 0.38 10.7 0.2 0.38 10.7 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Zn_Tnp_IS1 PF03811.8 EDO16816.1 - 0.44 10.0 5.0 9.5 5.8 0.0 3.2 3 0 0 3 3 3 0 InsA N-terminal domain TF_Zn_Ribbon PF08271.7 EDO16816.1 - 0.47 9.8 11.2 0.96 8.8 2.3 3.1 3 1 1 4 4 3 0 TFIIB zinc-binding zf-RanBP PF00641.13 EDO16816.1 - 0.53 9.4 8.6 3 7.0 0.0 3.5 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zinc_ribbon_2 PF13240.1 EDO16816.1 - 0.55 9.7 15.8 0.86 9.1 1.6 4.0 3 2 1 4 4 4 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 EDO16816.1 - 0.62 9.9 6.7 2.2 8.1 0.9 3.4 3 1 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like zf-CHY PF05495.7 EDO16816.1 - 0.71 10.0 5.9 7 6.8 0.1 2.6 2 1 0 2 2 2 0 CHY zinc finger OrfB_Zn_ribbon PF07282.6 EDO16816.1 - 0.83 9.3 6.8 9.1 6.0 0.1 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Ribosomal_S27e PF01667.12 EDO16816.1 - 0.88 9.1 6.9 5 6.7 0.1 3.4 3 1 1 4 4 4 0 Ribosomal protein S27 zf-C4_Topoisom PF01396.14 EDO16816.1 - 1 8.9 10.6 1.3 8.6 4.1 3.0 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger PolC_DP2 PF03833.8 EDO16816.1 - 1.2 6.7 3.6 0.52 7.9 0.6 1.6 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 Baculo_LEF5_C PF11792.3 EDO16816.1 - 1.2 8.6 6.2 0.25 10.7 0.4 2.6 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Cys_rich_KTR PF14205.1 EDO16816.1 - 1.3 8.5 4.2 15 5.1 0.1 3.0 3 0 0 3 3 3 0 Cysteine-rich KTR HypA PF01155.14 EDO16816.1 - 1.3 8.7 7.9 14 5.4 0.2 2.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-MYND PF01753.13 EDO16816.1 - 1.3 8.9 5.5 8.2 6.3 0.3 2.5 2 1 0 2 2 2 0 MYND finger zf-H2C2_2 PF13465.1 EDO16816.1 - 1.5 9.2 13.6 0.24 11.7 1.2 3.4 2 1 1 3 3 3 0 Zinc-finger double domain Ogr_Delta PF04606.7 EDO16816.1 - 1.6 8.4 7.4 2.4 7.8 2.7 2.6 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger VP_N-CPKC PF11475.3 EDO16816.1 - 1.8 8.1 7.6 3.8 7.1 0.1 3.1 3 0 0 3 3 3 0 Virion protein N terminal domain zf-ISL3 PF14690.1 EDO16816.1 - 2.2 8.4 4.7 3.8 7.6 0.1 2.9 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc-ribbons_6 PF07191.7 EDO16816.1 - 2.8 7.7 12.7 1.6 8.5 0.1 3.1 3 1 0 3 3 2 0 zinc-ribbons Nudix_N_2 PF14803.1 EDO16816.1 - 3.1 7.5 8.4 35 4.1 0.0 3.9 4 0 0 4 4 4 0 Nudix N-terminal Prok-RING_1 PF14446.1 EDO16816.1 - 3.3 7.4 9.3 32 4.3 0.1 3.5 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-AN1 PF01428.11 EDO16816.1 - 4.6 7.1 8.2 68 3.4 0.1 3.4 3 1 0 3 3 3 0 AN1-like Zinc finger PADR1 PF08063.7 EDO16816.1 - 8.4 5.8 8.2 6.4 6.2 0.0 3.4 3 1 1 4 4 4 0 PADR1 (NUC008) domain A2L_zn_ribbon PF08792.5 EDO16816.1 - 10 5.7 14.1 19 4.8 0.2 4.0 4 0 0 4 4 4 0 A2L zinc ribbon domain CN_hydrolase PF00795.17 EDO16817.1 - 2.1e-14 53.3 0.0 5.1e-14 52.0 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase CHASE4 PF05228.8 EDO16817.1 - 0.079 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 CHASE4 domain LicD PF04991.8 EDO16818.1 - 3.1e-52 177.6 3.3 3.1e-52 177.6 2.3 5.0 3 1 0 3 3 3 1 LicD family Asp-B-Hydro_N PF05279.6 EDO16818.1 - 0.19 11.5 52.2 0.39 10.5 36.2 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pkinase PF00069.20 EDO16819.1 - 5.2e-41 140.5 0.0 1.1e-40 139.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16819.1 - 1.1e-15 57.4 0.0 1.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO16819.1 - 2.3e-05 23.4 0.0 4.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO16819.1 - 0.003 16.6 0.0 0.0056 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EDO16819.1 - 0.0075 15.6 0.0 0.034 13.4 0.0 1.9 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EDO16819.1 - 0.071 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA PF00004.24 EDO16820.1 - 5.1e-52 175.5 0.1 1.5e-42 144.9 0.0 3.3 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EDO16820.1 - 1.4e-25 89.0 0.2 6.4e-25 87.0 0.0 2.3 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EDO16820.1 - 3e-13 50.1 0.8 1.7e-05 24.8 0.0 4.0 3 2 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EDO16820.1 - 6.9e-10 39.7 3.2 3.4e-05 24.6 0.1 3.7 4 1 0 4 4 2 2 AAA domain AAA_14 PF13173.1 EDO16820.1 - 7e-09 35.6 2.7 0.00035 20.4 0.1 3.8 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EDO16820.1 - 5.7e-07 29.7 2.6 0.0098 16.0 0.0 3.8 3 2 0 3 3 2 2 AAA domain NACHT PF05729.7 EDO16820.1 - 1.1e-06 28.4 0.1 0.012 15.2 0.0 3.5 3 0 0 3 3 3 2 NACHT domain AAA_18 PF13238.1 EDO16820.1 - 1.5e-05 25.3 7.9 0.0013 19.0 0.0 4.2 5 0 0 5 5 4 2 AAA domain NB-ARC PF00931.17 EDO16820.1 - 4.5e-05 22.4 0.0 0.12 11.1 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain AAA_33 PF13671.1 EDO16820.1 - 5.3e-05 23.1 0.0 0.32 10.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 EDO16820.1 - 0.00035 20.7 0.0 1.4 9.1 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.9 EDO16820.1 - 0.00039 20.1 0.0 0.87 9.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDO16820.1 - 0.00057 19.8 0.0 0.016 15.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EDO16820.1 - 0.00059 19.3 0.0 0.68 9.3 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 EDO16820.1 - 0.00083 18.9 0.0 0.45 9.9 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EDO16820.1 - 0.0011 18.6 2.7 0.33 10.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.21 EDO16820.1 - 0.0015 18.0 0.0 1.5 8.2 0.0 3.0 2 0 0 2 2 2 1 Sigma-54 interaction domain RuvB_N PF05496.7 EDO16820.1 - 0.0079 15.2 0.0 0.12 11.4 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 EDO16820.1 - 0.012 14.7 0.0 0.075 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 T2SE PF00437.15 EDO16820.1 - 0.013 14.4 0.3 0.75 8.6 0.1 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_28 PF13521.1 EDO16820.1 - 0.013 15.4 0.0 7 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EDO16820.1 - 0.014 15.1 0.0 0.25 11.0 0.0 2.5 2 0 0 2 2 2 0 NTPase UPF0079 PF02367.12 EDO16820.1 - 0.014 15.0 0.0 6.3 6.4 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EDO16820.1 - 0.016 14.7 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EDO16820.1 - 0.022 14.1 0.3 13 5.0 0.1 3.2 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.1 EDO16820.1 - 0.023 14.4 0.0 7.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_3 PF07726.6 EDO16820.1 - 0.042 13.4 0.0 9.4 5.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EDO16820.1 - 0.048 12.7 0.0 3.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Vps4_C PF09336.5 EDO16820.1 - 0.077 12.8 0.1 0.41 10.5 0.1 2.3 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.16 EDO16820.1 - 0.1 11.7 0.0 3.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EDO16820.1 - 0.33 11.2 0.1 0.33 11.2 0.1 4.7 5 2 0 5 5 3 0 ABC transporter Rieske PF00355.21 EDO16821.1 - 2.6e-18 65.3 0.0 4.1e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EDO16821.1 - 8.4e-18 64.3 2.2 1.3e-17 63.7 1.5 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Sec7 PF01369.15 EDO16822.1 - 1.2e-62 210.9 1.2 4.5e-62 209.1 0.9 2.0 1 0 0 1 1 1 1 Sec7 domain HC2 PF07382.6 EDO16822.1 - 1.3 8.8 7.3 2.1 8.1 5.1 1.2 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 OMPdecase PF00215.19 EDO16823.1 - 6.6e-77 257.9 0.0 7.6e-77 257.7 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family zf-Tim10_DDP PF02953.10 EDO16824.1 - 1.1e-21 75.8 6.4 1.5e-21 75.3 4.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1178 PF06676.6 EDO16824.1 - 0.026 14.6 0.4 0.038 14.1 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Mmp37 PF09139.6 EDO16824.1 - 0.038 13.0 0.6 0.04 12.9 0.4 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Phasin_2 PF09361.5 EDO16824.1 - 0.072 13.1 0.2 0.24 11.4 0.0 1.8 1 1 1 2 2 2 0 Phasin protein Ku_PK_bind PF08785.6 EDO16824.1 - 0.2 11.5 2.9 0.22 11.4 2.0 1.1 1 0 0 1 1 1 0 Ku C terminal domain like Vicilin_N PF04702.7 EDO16824.1 - 0.31 10.6 6.8 0.39 10.3 4.7 1.2 1 0 0 1 1 1 0 Vicilin N terminal region DUF842 PF05811.8 EDO16824.1 - 0.61 9.5 8.5 1.5 8.3 5.9 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) IDEAL PF08858.5 EDO16824.1 - 1.6 8.3 5.2 0.33 10.4 0.3 2.3 3 0 0 3 3 3 0 IDEAL domain tRNA-synt_2 PF00152.15 EDO16825.1 - 7.4e-72 241.9 0.0 9.8e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDO16825.1 - 1.7e-09 37.4 0.1 3.6e-09 36.3 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDO16825.1 - 0.026 13.7 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) zf-Nse PF11789.3 EDO16826.1 - 7.7e-16 57.3 0.2 1.8e-15 56.1 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EDO16826.1 - 0.0038 16.9 0.1 0.011 15.3 0.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.10 EDO16826.1 - 0.0049 16.7 0.1 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 U-box domain zf-MIZ PF02891.15 EDO16826.1 - 0.057 12.9 0.0 0.19 11.2 0.0 1.9 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Imm6 PF14434.1 EDO16827.1 - 0.016 14.8 0.2 0.031 14.0 0.1 1.4 1 0 0 1 1 1 0 Immunity protein Imm6 Phosphodiest PF01663.17 EDO16828.1 - 1.8e-73 247.9 0.6 2.7e-73 247.3 0.4 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EDO16828.1 - 0.0005 19.3 3.1 0.00061 19.0 0.1 2.4 2 0 0 2 2 2 1 Sulfatase Nop14 PF04147.7 EDO16828.1 - 0.092 10.6 20.1 0.14 10.1 14.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 EDO16828.1 - 0.11 11.9 21.7 0.21 10.9 15.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EDO16828.1 - 0.15 10.0 13.4 0.22 9.5 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EDO16828.1 - 0.19 10.1 22.3 0.28 9.6 15.4 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EDO16828.1 - 0.64 9.2 19.1 1.1 8.5 13.2 1.3 1 0 0 1 1 1 0 SDA1 Zip PF02535.17 EDO16828.1 - 0.89 8.4 2.5 1.4 7.8 1.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2201_N PF13203.1 EDO16828.1 - 1.5 7.9 11.0 3.1 6.8 7.7 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain Trypan_PARP PF05887.6 EDO16828.1 - 2.4 7.9 12.3 4.9 6.9 8.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ras PF00071.17 EDO16829.1 - 9.3e-38 129.1 0.1 1.6e-37 128.4 0.1 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDO16829.1 - 9.7e-15 55.1 0.1 1.7e-14 54.3 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EDO16829.1 - 4.1e-08 32.8 0.1 5.7e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EDO16829.1 - 3.8e-07 29.5 0.1 4.8e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDO16829.1 - 0.00023 21.0 0.0 0.0004 20.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase YjeF_N PF03853.10 EDO16830.1 - 3.7e-35 121.0 0.0 6.1e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EDO16830.1 - 3.7e-07 30.6 12.1 3.7e-07 30.6 8.4 2.1 2 0 0 2 2 2 1 FDF domain Arm PF00514.18 EDO16831.1 - 2.3e-71 233.3 26.8 4.4e-12 45.3 0.0 10.9 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EDO16831.1 - 9.4e-25 86.7 8.6 4.3e-07 30.1 0.0 7.7 3 2 5 8 8 8 6 HEAT repeats HEAT PF02985.17 EDO16831.1 - 3e-16 57.9 25.3 0.012 15.6 0.0 10.7 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 EDO16831.1 - 3.6e-16 59.1 13.3 0.00025 21.4 0.2 8.4 7 1 2 9 9 9 4 HEAT-like repeat Adaptin_N PF01602.15 EDO16831.1 - 1.2e-13 50.2 17.6 1.1e-07 30.5 0.9 2.8 1 1 2 3 3 3 3 Adaptin N terminal region Arm_2 PF04826.8 EDO16831.1 - 2.9e-11 42.9 7.4 0.00013 21.1 0.0 3.8 3 1 1 4 4 4 3 Armadillo-like KAP PF05804.7 EDO16831.1 - 3.1e-11 41.9 1.1 1.3e-09 36.6 0.1 2.4 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) RIX1 PF08167.7 EDO16831.1 - 8.2e-05 22.3 1.8 0.0017 18.0 0.2 3.3 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.2 EDO16831.1 - 0.0001 22.6 0.3 0.96 9.8 0.0 3.7 3 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region DUF2454 PF10521.4 EDO16831.1 - 0.00024 20.1 0.2 0.076 12.0 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2454) V-ATPase_H_C PF11698.3 EDO16831.1 - 0.0031 17.4 4.2 0.34 10.8 0.0 4.6 3 2 4 7 7 7 1 V-ATPase subunit H Smr PF01713.16 EDO16832.1 - 6.9e-15 55.0 0.0 1.4e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 EDO16832.1 - 4e-08 32.5 3.3 0.0069 15.8 0.0 3.5 4 0 0 4 4 4 2 CUE domain UBA PF00627.26 EDO16832.1 - 0.077 12.8 0.0 0.49 10.3 0.0 2.4 3 0 0 3 3 3 0 UBA/TS-N domain HECT PF00632.20 EDO16833.1 - 1.3e-76 257.7 1.9 1.7e-76 257.3 0.5 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Ribosomal_L10 PF00466.15 EDO16834.1 - 8.6e-17 60.9 0.0 1.5e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Dynactin_p22 PF07426.6 EDO16834.1 - 0.045 13.0 0.0 2 7.6 0.0 2.7 2 1 1 3 3 3 0 Dynactin subunit p22 TRAM_LAG1_CLN8 PF03798.11 EDO16835.1 - 4.7e-37 127.4 24.3 4.7e-37 127.4 16.8 2.4 2 1 1 3 3 3 1 TLC domain TRAM1 PF08390.6 EDO16835.1 - 6.2e-24 83.2 2.4 1.7e-23 81.9 1.7 1.8 1 0 0 1 1 1 1 TRAM1-like protein MOSP_C PF02722.10 EDO16835.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal region Tmemb_9 PF05434.6 EDO16835.1 - 0.14 11.8 0.3 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 TMEM9 Herpes_LMP1 PF05297.6 EDO16835.1 - 4.8 5.9 7.0 7.9 5.2 4.8 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) VHS PF00790.14 EDO16836.1 - 1.2e-32 112.4 2.6 1.7e-32 112.0 1.3 1.7 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 EDO16836.1 - 1.5e-15 56.3 0.0 2.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO16836.1 - 1.3e-13 50.2 0.0 2.6e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDO16836.1 - 1.8e-12 46.5 0.0 3.5e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF605 PF04652.11 EDO16836.1 - 0.00066 19.1 10.3 0.00066 19.1 7.2 2.1 2 0 0 2 2 2 1 Vta1 like DUF310 PF03750.8 EDO16836.1 - 0.013 15.7 2.4 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF310) Hrs_helical PF12210.3 EDO16836.1 - 0.049 13.8 0.5 0.16 12.2 0.2 2.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate UIM PF02809.15 EDO16836.1 - 0.051 13.1 1.2 0.14 11.8 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin interaction motif Suf PF05843.9 EDO16836.1 - 0.069 12.8 25.5 0.73 9.5 6.0 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) F-actin_cap_A PF01267.12 EDO16837.1 - 3.9e-81 272.0 5.4 4.5e-81 271.8 3.7 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit ACCA PF03255.9 EDO16837.1 - 0.41 10.2 2.0 0.29 10.6 0.1 1.6 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SNARE PF05739.14 EDO16838.1 - 0.0056 16.3 2.0 0.0068 16.0 1.4 1.1 1 0 0 1 1 1 1 SNARE domain DUF4492 PF14899.1 EDO16838.1 - 0.026 14.0 0.4 0.054 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) LETM1 PF07766.8 EDO16838.1 - 0.034 13.1 0.1 0.038 13.0 0.1 1.1 1 0 0 1 1 1 0 LETM1-like protein Use1 PF09753.4 EDO16838.1 - 0.039 13.3 0.1 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF912 PF06024.7 EDO16838.1 - 0.043 13.8 0.1 0.05 13.6 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Latarcin PF10279.4 EDO16838.1 - 0.069 13.3 0.9 0.21 11.8 0.6 1.8 1 1 0 1 1 1 0 Latarcin precursor Synaptobrevin PF00957.16 EDO16838.1 - 0.079 12.5 2.5 0.18 11.4 1.5 1.8 1 1 1 2 2 2 0 Synaptobrevin Ribosomal_L14e PF01929.12 EDO16839.1 - 1.6e-30 105.2 0.7 2.5e-30 104.6 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EDO16839.1 - 0.00038 20.0 0.8 0.00091 18.8 0.6 1.7 1 0 0 1 1 1 1 KOW motif DUF3176 PF11374.3 EDO16839.1 - 0.13 12.1 0.5 0.28 11.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) PAP2 PF01569.16 EDO16840.1 - 3.2e-12 46.2 7.1 3.2e-12 46.2 4.9 2.3 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EDO16840.1 - 0.0019 17.7 6.0 0.0019 17.7 4.2 2.3 2 1 0 2 2 2 1 PAP2 superfamily Peptidase_U4 PF03419.8 EDO16840.1 - 2.4 7.1 7.9 0.16 10.9 1.4 1.9 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Dynamin_M PF01031.15 EDO16841.1 - 8.5e-105 349.7 0.4 1.6e-104 348.8 0.3 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EDO16841.1 - 1.3e-54 184.5 0.2 3e-54 183.3 0.2 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EDO16841.1 - 1.7e-27 95.0 3.7 4.6e-27 93.7 2.6 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EDO16841.1 - 0.0017 18.2 0.6 0.043 13.7 0.4 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDO16841.1 - 0.026 14.9 0.0 0.074 13.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein PAP_central PF04928.12 EDO16842.1 - 9.6e-110 365.3 0.0 2.1e-109 364.1 0.0 1.6 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EDO16842.1 - 7.4e-48 162.0 0.7 1.3e-47 161.2 0.5 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EDO16842.1 - 1.8e-12 47.4 1.3 3.6e-12 46.4 0.1 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain JAB PF01398.16 EDO16843.1 - 6e-34 116.2 0.3 6e-34 116.2 0.2 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EDO16843.1 - 6.8e-25 87.3 5.5 2e-24 85.8 3.8 1.8 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EDO16843.1 - 1.4e-08 34.2 0.0 2.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EDO16843.1 - 0.022 14.2 2.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) UCH PF00443.24 EDO16844.1 - 1e-14 54.3 2.9 2.1e-14 53.2 2.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EDO16844.1 - 1.4e-11 44.3 0.2 2.6e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Peptidase_M24 PF00557.19 EDO16845.1 - 3.8e-58 196.4 0.0 5.5e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EDO16845.1 - 1.1e-26 92.8 0.0 4.5e-26 90.8 0.0 2.0 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Ribonuc_red_sm PF00268.16 EDO16846.1 - 6.7e-57 192.6 4.3 8e-57 192.3 3.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Mt_ATP-synt_D PF05873.7 EDO16846.1 - 0.0095 15.5 1.8 0.013 15.1 0.2 1.9 2 0 0 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) TGS PF02824.16 EDO16847.1 - 8.2e-20 70.4 0.0 1.8e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EDO16847.1 - 3e-19 69.0 0.5 8.7e-19 67.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO16847.1 - 3.6e-13 49.0 0.0 6e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDO16847.1 - 3e-05 23.9 0.7 0.017 14.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 EDO16847.1 - 0.0003 19.9 0.1 0.00053 19.1 0.1 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EDO16847.1 - 0.00069 20.1 0.2 0.0024 18.3 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EDO16847.1 - 0.00074 18.7 1.0 0.0049 16.0 0.0 2.2 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MCM PF00493.18 EDO16847.1 - 0.012 14.4 0.4 0.029 13.1 0.0 1.7 2 0 0 2 2 2 0 MCM2/3/5 family Ras PF00071.17 EDO16847.1 - 0.076 12.4 0.4 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Ras family Retrotrans_gag PF03732.12 EDO16848.1 - 3.5e-07 30.1 0.1 5.9e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EDO16848.1 - 0.00023 20.9 2.6 0.00038 20.2 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EDO16848.1 - 0.0053 16.2 2.7 0.01 15.2 1.9 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger ComJ PF11033.3 EDO16848.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.7 2 0 0 2 2 2 0 Competence protein J (ComJ) Flocculin PF00624.13 EDO16849.1 - 2.2e-129 421.1 499.2 1.1e-11 44.3 11.6 72.6 43 10 31 74 74 74 24 Flocculin repeat Homoserine_dh PF00742.14 EDO16850.1 - 2e-52 177.4 0.0 2.7e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EDO16850.1 - 1.4e-21 77.0 0.0 2.4e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EDO16850.1 - 0.059 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent VWA_2 PF13519.1 EDO16851.1 - 5.3e-10 39.6 0.2 7.2e-10 39.2 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EDO16851.1 - 1.6e-07 31.1 1.0 2.4e-07 30.5 0.7 1.3 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 EDO16851.1 - 0.032 13.8 1.5 0.071 12.7 1.1 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif Birna_VP3 PF01767.11 EDO16851.1 - 0.069 12.7 0.1 0.069 12.7 0.1 1.5 2 0 0 2 2 2 0 Birnavirus VP3 protein zf-Tim10_DDP PF02953.10 EDO16852.1 - 7e-09 34.8 0.1 7e-09 34.8 0.1 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Rsd_AlgQ PF04353.8 EDO16853.1 - 0.0056 16.3 0.6 0.011 15.3 0.4 1.5 1 0 0 1 1 1 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ KxDL PF10241.4 EDO16853.1 - 0.044 13.6 1.0 0.11 12.4 0.7 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein HAUS-augmin3 PF14932.1 EDO16853.1 - 0.046 12.8 3.8 0.058 12.5 2.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 RIX1 PF08167.7 EDO16854.1 - 1.8e-46 157.8 8.3 1.8e-46 157.8 5.7 2.0 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF281 PF03436.8 EDO16854.1 - 0.14 12.2 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF281) PIP5K PF01504.13 EDO16856.1 - 2.5e-66 223.3 2.4 1.3e-65 221.0 1.7 2.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EDO16856.1 - 2.1e-29 102.5 0.7 3.8e-29 101.6 0.5 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EDO16856.1 - 6.7e-17 61.1 9.7 6.7e-17 61.1 6.7 2.2 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EDO16856.1 - 0.69 9.7 8.1 1.6 8.6 5.6 1.6 1 0 0 1 1 1 0 Ring finger domain IBR PF01485.16 EDO16856.1 - 0.99 9.3 10.3 0.27 11.1 4.4 2.1 2 0 0 2 2 2 0 IBR domain Peptidase_M28 PF04389.12 EDO16857.1 - 2.5e-27 95.7 0.0 3.5e-27 95.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 TIP120 PF08623.5 EDO16858.1 - 2.7e-05 23.8 0.4 2.7e-05 23.8 0.3 2.5 2 1 0 2 2 2 1 TATA-binding protein interacting (TIP20) NGF PF00243.13 EDO16859.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Nerve growth factor family RRP7 PF12923.2 EDO16859.1 - 2.3 8.2 9.8 5.2 7.1 1.2 2.3 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) GTP_EFTU PF00009.22 EDO16860.1 - 2.3e-33 115.2 6.2 2.1e-32 112.0 4.3 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EDO16860.1 - 2.9e-24 85.0 1.1 8e-24 83.6 0.8 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EDO16860.1 - 3e-10 40.0 6.5 5.7e-06 26.3 0.0 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EDO16860.1 - 2.8e-07 30.0 0.4 7.3e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EDO16860.1 - 9.5e-07 28.7 0.6 3.3e-06 27.0 0.4 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDO16860.1 - 4.5e-05 23.9 0.4 4.5e-05 23.9 0.3 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EDO16860.1 - 0.0015 18.3 5.1 0.92 9.3 0.1 4.3 3 1 1 4 4 4 2 Dynamin family Ras PF00071.17 EDO16860.1 - 0.0018 17.6 0.1 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 Ras family PDCD2_C PF04194.8 EDO16861.1 - 7.6e-41 139.4 7.2 4.1e-40 137.0 0.0 3.2 2 1 1 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain Protein_K PF12283.3 EDO16862.1 - 0.037 13.8 7.0 0.049 13.5 1.3 2.7 3 0 0 3 3 3 0 Bacteriophage protein K BBP1_N PF15271.1 EDO16862.1 - 0.27 11.5 12.0 0.57 10.5 8.3 1.5 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein ubiquitin PF00240.18 EDO16863.1 - 6.4e-35 118.3 0.7 1.3e-34 117.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EDO16863.1 - 7.5e-26 89.6 2.1 1.4e-25 88.8 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EDO16863.1 - 1.4e-19 69.5 0.7 1.4e-19 69.5 0.5 1.7 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDO16863.1 - 9.4e-06 25.7 0.3 4.5e-05 23.6 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDO16863.1 - 0.00019 21.1 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDO16863.1 - 0.00099 18.9 0.4 0.0023 17.7 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDO16863.1 - 0.005 17.0 0.5 0.0066 16.6 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EDO16863.1 - 0.048 13.5 0.5 0.071 13.0 0.4 1.3 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 EDO16863.1 - 0.065 13.2 0.3 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) DUF2207 PF09972.4 EDO16863.1 - 0.098 11.2 0.8 0.11 11.0 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Plexin_cytopl PF08337.7 EDO16863.1 - 0.27 9.5 2.7 3.1 6.0 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Thioredoxin PF00085.15 EDO16864.1 - 0.023 14.3 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DIM1 PF02966.11 EDO16864.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 Sec10 PF07393.6 EDO16865.1 - 3.3e-189 630.5 32.2 4.4e-189 630.1 22.4 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 SAS4 PF15460.1 EDO16866.1 - 6e-31 106.3 6.8 6e-31 106.3 4.7 2.3 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 CybS PF05328.7 EDO16868.1 - 2.5e-47 159.8 0.0 2.9e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 CybS Peptidase_M16 PF00675.15 EDO16869.1 - 3.4e-53 179.4 0.2 1.1e-52 177.7 0.0 2.0 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDO16869.1 - 2.1e-38 131.8 0.1 9.1e-36 123.2 0.0 3.0 3 0 0 3 3 3 1 Peptidase M16 inactive domain Luteo_P1-P2 PF08467.5 EDO16869.1 - 0.002 17.0 0.2 0.0032 16.3 0.1 1.4 1 0 0 1 1 1 1 Luteovirus RNA polymerase P1-P2/replicase NAGidase PF07555.8 EDO16869.1 - 0.011 14.7 0.1 0.11 11.3 0.0 2.1 2 0 0 2 2 2 0 beta-N-acetylglucosaminidase HMG_box PF00505.14 EDO16870.1 - 8.7e-11 41.9 4.7 8.7e-11 41.9 3.2 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO16870.1 - 4.5e-08 33.3 3.3 4.5e-08 33.3 2.3 1.9 2 0 0 2 2 2 1 HMG-box domain UvrD_C PF13361.1 EDO16870.1 - 0.0027 17.2 0.9 0.0027 17.2 0.6 1.7 1 1 1 2 2 2 1 UvrD-like helicase C-terminal domain Mit_KHE1 PF10173.4 EDO16870.1 - 0.65 9.8 11.0 1.1 9.1 1.9 2.6 2 1 1 3 3 3 0 Mitochondrial K+-H+ exchange-related FliD_N PF02465.13 EDO16870.1 - 2.2 8.7 11.5 0.065 13.6 3.1 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus IPK PF03770.11 EDO16871.1 - 2.1e-57 193.9 0.2 3.7e-57 193.1 0.2 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Nucleoplasmin PF03066.10 EDO16871.1 - 2.4 7.6 15.3 3.3 7.2 2.5 2.6 2 0 0 2 2 2 0 Nucleoplasmin HSP20 PF00011.16 EDO16872.1 - 1.3e-06 28.1 0.3 3.2e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Hsp20/alpha crystallin family DUF290 PF01060.18 EDO16872.1 - 0.11 12.5 1.2 11 6.1 0.2 2.9 2 1 0 2 2 2 0 Transthyretin-like family Ceramidase PF05875.7 EDO16873.1 - 1.2e-99 332.6 20.9 1.4e-99 332.4 14.5 1.0 1 0 0 1 1 1 1 Ceramidase DUF4199 PF13858.1 EDO16873.1 - 0.006 16.5 6.5 0.006 16.5 4.5 2.6 1 1 2 3 3 3 1 Protein of unknown function (DUF4199) TcpE PF12648.2 EDO16873.1 - 0.0069 16.5 2.0 0.0069 16.5 1.4 2.6 1 1 2 3 3 3 1 TcpE family VIT1 PF01988.14 EDO16873.1 - 0.025 14.0 1.0 0.025 14.0 0.7 1.7 2 0 0 2 2 2 0 VIT family DUF1056 PF06341.6 EDO16873.1 - 0.043 13.8 1.5 0.043 13.8 1.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1056) MerC PF03203.9 EDO16873.1 - 0.14 12.4 7.4 1.7 9.0 0.4 2.4 2 0 0 2 2 2 0 MerC mercury resistance protein Radical_SAM PF04055.16 EDO16874.1 - 1.1e-17 64.6 0.1 2.7e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EDO16874.1 - 2.4e-11 43.5 0.0 6.9e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO16874.1 - 0.1 12.7 0.1 0.28 11.3 0.1 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec16_C PF12931.2 EDO16875.1 - 5.3e-25 88.7 0.6 1.1e-24 87.6 0.4 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 MBA1 PF07961.6 EDO16876.1 - 1.4e-97 325.1 3.7 1.7e-97 324.8 2.6 1.0 1 0 0 1 1 1 1 MBA1-like protein BRO1 PF03097.13 EDO16877.1 - 9.2e-91 304.3 9.0 9.2e-91 304.3 6.3 1.9 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EDO16877.1 - 6.7e-48 163.1 20.8 6.7e-48 163.1 14.4 2.1 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV UPF0016 PF01169.14 EDO16878.1 - 1.7e-40 137.0 20.6 7.4e-21 74.0 4.2 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 cwf18 PF08315.7 EDO16879.1 - 0.26 11.7 10.1 0.39 11.1 7.0 1.3 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor DUF663 PF04950.7 EDO16879.1 - 0.71 8.7 2.6 0.53 9.1 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF663) Ribosomal_S4 PF00163.14 EDO16880.1 - 2e-26 92.2 1.9 3e-26 91.6 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EDO16880.1 - 1.5e-13 49.9 1.8 1.7e-13 49.7 0.1 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_L21e PF01157.13 EDO16881.1 - 1.9e-45 152.6 6.4 2.3e-45 152.4 4.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.4 EDO16881.1 - 0.0069 15.7 0.1 0.0084 15.4 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Mito_carr PF00153.22 EDO16882.1 - 1.9e-78 258.2 3.3 1.1e-28 98.8 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Med8 PF10232.4 EDO16883.1 - 9e-45 152.9 1.5 1.2e-44 152.4 1.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 NPV_P10 PF05531.7 EDO16883.1 - 0.0096 16.1 2.0 0.69 10.2 0.0 2.9 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Mt_ATP-synt_B PF05405.9 EDO16884.1 - 4.7e-55 185.5 10.3 5.6e-55 185.2 7.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SRX PF09201.5 EDO16884.1 - 0.005 16.5 1.9 0.0075 15.9 1.4 1.3 1 0 0 1 1 1 1 SRX GM_CSF PF01109.12 EDO16884.1 - 0.13 12.2 0.4 0.37 10.7 0.3 1.8 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor WD40 PF00400.27 EDO16885.1 - 3.1e-26 90.2 9.7 1.1e-05 25.1 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EDO16885.1 - 7.7e-17 60.9 0.6 2.6e-16 59.2 0.7 1.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EDO16885.1 - 4.1e-07 29.9 0.3 6.5e-05 22.7 0.0 3.2 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EDO16885.1 - 0.00011 20.5 0.4 0.0011 17.2 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EDO16885.1 - 0.00071 18.4 0.0 0.025 13.3 0.0 2.1 1 1 1 2 2 2 1 Coatomer WD associated region Apc4_WD40 PF12894.2 EDO16885.1 - 0.02 14.3 0.0 1.7 8.2 0.0 3.7 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain LigD_N PF13298.1 EDO16885.1 - 0.093 12.8 0.4 0.5 10.4 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase Ligase (LigD) PGI PF00342.14 EDO16886.1 - 9.3e-221 733.4 0.8 1.1e-220 733.1 0.5 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase COG5 PF10392.4 EDO16887.1 - 0.0027 17.6 0.1 0.0027 17.6 0.1 2.1 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Ferritin PF00210.19 EDO16887.1 - 0.065 12.9 0.7 0.12 12.1 0.5 1.4 1 0 0 1 1 1 0 Ferritin-like domain DUF2018 PF09442.5 EDO16887.1 - 0.16 12.5 4.1 2.6 8.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) Peptidase_C6 PF00851.13 EDO16887.1 - 0.49 8.9 7.2 0.11 11.1 3.0 1.4 2 0 0 2 2 2 0 Helper component proteinase RhoGEF PF00621.15 EDO16887.1 - 0.54 10.1 7.7 2.6 7.8 5.3 2.2 1 1 0 1 1 1 0 RhoGEF domain Snapin_Pallidin PF14712.1 EDO16887.1 - 0.75 10.1 6.9 9.2 6.6 3.0 3.2 3 1 0 3 3 3 0 Snapin/Pallidin DUF2422 PF10337.4 EDO16887.1 - 6.6 5.4 7.0 37 2.9 4.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) WD40 PF00400.27 EDO16888.1 - 7.8e-61 199.9 16.8 5.2e-11 41.9 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EDO16888.1 - 2.1e-48 164.0 3.7 5.6e-48 162.6 2.6 1.7 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EDO16888.1 - 2.1e-07 30.4 0.1 4.5e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 EDO16888.1 - 2.3e-06 27.4 4.6 0.00096 18.9 0.6 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A HeLo PF14479.1 EDO16889.1 - 0.081 12.6 2.8 0.24 11.0 2.0 1.9 1 1 0 1 1 1 0 Prion-inhibition and propagation UCH PF00443.24 EDO16890.1 - 8.6e-37 126.7 9.0 1.1e-36 126.4 6.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO16890.1 - 3.8e-12 46.2 7.5 2.6e-11 43.5 5.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SH3_1 PF00018.23 EDO16891.1 - 4.7e-22 77.1 0.0 5e-10 38.6 0.0 2.8 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EDO16891.1 - 1.1e-15 56.9 0.2 1.3e-10 40.6 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EDO16891.1 - 1.8e-15 56.7 0.0 4e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EDO16891.1 - 7.9e-10 38.0 0.1 1.9e-07 30.4 0.0 3.1 3 0 0 3 3 3 1 Variant SH3 domain PB1 PF00564.19 EDO16891.1 - 9.4e-07 28.4 0.0 1.9e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 PB1 domain VPS9 PF02204.13 EDO16893.1 - 7.7e-18 64.4 4.6 1.2e-17 63.8 2.1 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain UPF0546 PF10639.4 EDO16893.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 MEDS PF14417.1 EDO16894.1 - 0.025 13.6 0.2 0.16 11.0 0.0 2.1 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain AvrB_AvrC PF05394.6 EDO16895.1 - 0.054 12.4 0.7 0.092 11.7 0.5 1.3 1 0 0 1 1 1 0 Avirulence protein ATP-synt_ab PF00006.20 EDO16896.1 - 3.6e-119 395.9 0.0 2.7e-118 393.1 0.0 2.3 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.11 EDO16896.1 - 1.5e-70 237.3 0.0 3e-70 236.3 0.0 1.6 1 1 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.9 EDO16896.1 - 7.2e-45 151.4 0.4 5e-33 113.3 0.1 2.6 2 0 0 2 2 2 2 Homing endonuclease ATP-synt_ab_C PF00306.22 EDO16896.1 - 1.8e-19 70.3 0.1 5.5e-19 68.7 0.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDO16896.1 - 4e-16 58.9 2.4 1.2e-15 57.4 1.6 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.1 EDO16896.1 - 2e-08 34.3 0.2 6.6e-05 23.0 0.0 2.7 2 0 0 2 2 2 2 LAGLIDADG-like domain Hint PF01079.15 EDO16896.1 - 0.00029 20.1 0.0 0.00071 18.8 0.0 1.6 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.1 EDO16896.1 - 0.0035 17.2 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 Hint domain LAGLIDADG_WhiA PF14527.1 EDO16896.1 - 0.016 15.0 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain WhiA_N PF10298.4 EDO16896.1 - 0.047 13.5 0.0 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain Ribosomal_L41 PF05162.8 EDO16897.1 - 9.5e-09 34.7 25.2 1e-08 34.7 17.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1601 PF07671.6 EDO16897.1 - 0.18 11.4 1.3 0.2 11.3 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1601) IATP PF04568.7 EDO16899.1 - 3.9e-21 74.9 1.4 4.1e-21 74.8 1.0 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Fib_alpha PF08702.5 EDO16899.1 - 0.0015 18.6 0.7 0.0015 18.6 0.5 1.1 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family IncA PF04156.9 EDO16899.1 - 0.0032 17.0 1.1 0.0032 17.0 0.7 1.1 1 0 0 1 1 1 1 IncA protein FbpA PF05833.6 EDO16899.1 - 0.0085 14.6 2.8 0.0084 14.6 2.0 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) RRP7 PF12923.2 EDO16899.1 - 0.03 14.3 3.6 0.034 14.1 2.5 1.1 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) CART PF06373.6 EDO16899.1 - 0.091 12.7 1.4 0.13 12.2 1.0 1.2 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) ABC_tran_2 PF12848.2 EDO16899.1 - 0.23 11.3 9.1 0.22 11.3 5.4 1.6 1 1 1 2 2 2 0 ABC transporter Bap31 PF05529.7 EDO16899.1 - 0.25 10.7 3.6 0.26 10.7 2.5 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF1049 PF06305.6 EDO16899.1 - 0.54 9.7 2.4 0.89 9.0 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DivIC PF04977.10 EDO16899.1 - 0.8 9.2 7.0 1 8.8 4.6 1.4 1 1 0 1 1 1 0 Septum formation initiator DASH_Dad2 PF08654.5 EDO16899.1 - 1.1 9.2 5.1 1.2 9.1 3.1 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad2 Cyclin_N PF00134.18 EDO16902.1 - 8.8e-15 54.4 0.0 1.3e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EDO16902.1 - 1.2e-09 38.7 0.7 2.2e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin AAA PF00004.24 EDO16903.1 - 8.2e-100 330.1 0.0 9e-49 165.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EDO16903.1 - 1.3e-18 66.6 0.6 3.4e-18 65.3 0.4 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EDO16903.1 - 1.9e-15 57.1 0.0 2.7e-07 30.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EDO16903.1 - 2e-13 49.9 0.0 1.4e-05 24.3 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDO16903.1 - 1.8e-12 47.1 3.3 1.9e-06 27.6 0.0 3.9 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO16903.1 - 2e-12 47.4 0.0 0.00043 20.3 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 EDO16903.1 - 7.8e-12 45.2 0.0 6.2e-06 26.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EDO16903.1 - 1.2e-11 45.4 0.1 0.00069 20.4 0.0 3.9 5 0 0 5 5 2 2 AAA domain AAA_22 PF13401.1 EDO16903.1 - 2.4e-10 40.6 4.2 0.0011 19.0 0.1 4.3 3 2 1 4 4 3 2 AAA domain TIP49 PF06068.8 EDO16903.1 - 2.3e-09 36.4 0.0 0.0012 17.6 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EDO16903.1 - 1.4e-08 34.7 0.0 0.0039 17.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain CDC48_2 PF02933.12 EDO16903.1 - 1.8e-08 33.8 0.0 4.8e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.1 EDO16903.1 - 7.2e-08 32.0 8.7 0.056 12.8 0.1 4.5 2 2 2 4 4 4 3 AAA domain IstB_IS21 PF01695.12 EDO16903.1 - 8.2e-08 31.8 0.1 0.007 15.7 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EDO16903.1 - 9.9e-08 32.1 0.0 0.0044 17.1 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 EDO16903.1 - 2.4e-07 30.4 0.9 0.025 14.3 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 EDO16903.1 - 4e-07 29.4 0.5 0.03 13.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EDO16903.1 - 4e-07 29.3 0.4 0.01 14.9 0.0 3.1 3 1 0 3 3 3 2 Zeta toxin KaiC PF06745.8 EDO16903.1 - 1.6e-06 27.3 4.2 0.24 10.4 0.0 4.5 3 2 2 5 5 5 2 KaiC AAA_24 PF13479.1 EDO16903.1 - 1.7e-06 27.7 0.0 0.093 12.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.22 EDO16903.1 - 2.5e-06 27.8 0.1 0.074 13.3 0.0 4.2 3 1 0 3 3 3 1 ABC transporter ResIII PF04851.10 EDO16903.1 - 7e-06 25.9 0.0 0.01 15.7 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EDO16903.1 - 7.8e-06 26.2 0.0 0.12 12.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EDO16903.1 - 8.1e-06 25.4 0.2 0.14 11.6 0.0 3.7 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_28 PF13521.1 EDO16903.1 - 1.1e-05 25.5 0.0 0.24 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 EDO16903.1 - 2.2e-05 23.4 0.1 0.11 11.3 0.0 2.5 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.11 EDO16903.1 - 2.8e-05 23.4 0.6 0.11 11.6 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 EDO16903.1 - 3.6e-05 23.8 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 EDO16903.1 - 3.8e-05 22.7 0.0 0.061 12.2 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_11 PF13086.1 EDO16903.1 - 4.2e-05 23.2 0.1 0.28 10.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain Vps4_C PF09336.5 EDO16903.1 - 4.8e-05 23.1 0.3 0.00053 19.8 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 EDO16903.1 - 6.2e-05 22.6 0.0 0.37 10.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EDO16903.1 - 6.7e-05 22.6 0.2 0.66 9.6 0.0 4.0 2 2 1 3 3 3 1 Archaeal ATPase NACHT PF05729.7 EDO16903.1 - 9.8e-05 22.0 0.2 1.6 8.3 0.0 3.9 4 0 0 4 4 4 1 NACHT domain Bac_DnaA PF00308.13 EDO16903.1 - 0.00013 21.7 0.0 0.28 10.8 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein DUF2075 PF09848.4 EDO16903.1 - 0.00043 19.3 0.0 0.6 9.0 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EDO16903.1 - 0.00055 19.5 0.0 1.5 8.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EDO16903.1 - 0.0042 15.9 0.2 1.6 7.4 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain IPT PF01745.11 EDO16903.1 - 0.014 14.6 0.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 EDO16903.1 - 0.02 14.3 0.4 5.4 6.4 0.0 3.7 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.9 EDO16903.1 - 0.021 13.8 0.4 1.7 7.5 0.0 3.0 2 2 2 4 4 4 0 KAP family P-loop domain Mrr_cat PF04471.7 EDO16903.1 - 0.036 13.8 0.2 13 5.5 0.0 3.0 3 0 0 3 3 2 0 Restriction endonuclease SKI PF01202.17 EDO16903.1 - 0.047 13.5 0.0 4.5 7.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 EDO16903.1 - 0.053 13.1 0.1 6.4 6.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EDO16903.1 - 0.061 13.0 4.7 3.2 7.4 0.0 4.5 5 0 0 5 5 4 0 NTPase DEAD PF00270.24 EDO16903.1 - 0.093 12.2 0.4 24 4.3 0.0 3.6 3 1 1 4 4 4 0 DEAD/DEAH box helicase UFD1 PF03152.9 EDO16903.1 - 0.12 11.5 0.0 0.66 9.0 0.0 1.9 1 1 0 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Viral_helicase1 PF01443.13 EDO16903.1 - 0.22 10.9 0.0 15 4.9 0.0 2.9 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase HIT PF01230.18 EDO16904.1 - 6e-25 87.6 0.1 7.7e-25 87.2 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EDO16904.1 - 5.5e-12 45.9 0.0 9.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EDO16904.1 - 0.00067 19.2 0.0 0.00094 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Aldo_ket_red PF00248.16 EDO16905.1 - 4.5e-48 163.5 0.0 5.5e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0029 PF01205.14 EDO16906.1 - 4.6e-32 109.9 0.1 9.8e-32 108.9 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized protein family UPF0029 Branch PF02485.16 EDO16906.1 - 0.02 14.0 0.1 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 Core-2/I-Branching enzyme Toxin_44 PF15523.1 EDO16906.1 - 0.06 13.2 0.5 0.13 12.1 0.1 1.7 2 0 0 2 2 2 0 Putative toxin 44 Pmp3 PF01679.12 EDO16907.1 - 6.1e-20 70.6 7.6 8.2e-20 70.2 5.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Cyclin_N PF00134.18 EDO16908.1 - 7.7e-20 70.7 0.0 1.6e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EDO16908.1 - 3.5e-13 50.2 0.0 7.8e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin TruB_N PF01509.13 EDO16909.1 - 4.7e-42 143.6 1.7 1.4e-38 132.3 0.0 3.3 2 1 0 3 3 3 2 TruB family pseudouridylate synthase (N terminal domain) PEPcase_2 PF14010.1 EDO16909.1 - 0.0051 15.1 1.3 0.0055 15.0 0.1 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate carboxylase RabGAP-TBC PF00566.13 EDO16910.1 - 1.3e-42 145.7 2.7 3.4e-42 144.3 1.9 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain YlzJ PF14035.1 EDO16910.1 - 0.027 14.5 0.0 0.076 13.0 0.0 1.8 1 0 0 1 1 1 0 YlzJ-like protein Sec7_N PF12783.2 EDO16911.1 - 1.4e-30 105.9 13.1 2.6e-30 105.0 4.6 3.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Ipi1_N PF12333.3 EDO16911.1 - 0.37 10.7 3.8 1 9.3 0.0 3.5 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation RF-1 PF00472.15 EDO16912.1 - 8.2e-13 48.1 0.3 1.3e-12 47.4 0.2 1.3 1 0 0 1 1 1 1 RF-1 domain NTP_transf_2 PF01909.18 EDO16913.1 - 2.9e-17 62.7 1.0 8.6e-17 61.2 0.1 2.4 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EDO16913.1 - 5e-16 58.4 0.3 1.8e-15 56.5 0.2 2.1 1 0 0 1 1 1 1 Cid1 family poly A polymerase GCR1_C PF12550.3 EDO16914.1 - 5.6e-25 87.0 0.5 1.3e-24 85.8 0.3 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes C6 PF01681.12 EDO16915.1 - 0.19 11.7 8.2 0.24 11.4 5.7 1.3 1 0 0 1 1 1 0 C6 domain DUF3677 PF12432.3 EDO16917.1 - 0.08 13.3 2.3 0.48 10.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3677) DUF2935 PF11155.3 EDO16917.1 - 0.12 12.4 2.5 5.1 7.2 0.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Redoxin PF08534.5 EDO16918.1 - 6e-29 100.4 0.0 6.9e-29 100.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EDO16918.1 - 1.2e-09 37.9 0.0 1.4e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family S-AdoMet_synt_C PF02773.11 EDO16918.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain Ribosomal_L18e PF00828.14 EDO16919.1 - 2.4e-25 89.3 0.1 3.8e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 MscL PF01741.13 EDO16919.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL zf-DHHC PF01529.15 EDO16919.1 - 0.26 10.6 1.3 0.4 10.0 0.9 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ldh_1_N PF00056.18 EDO16920.1 - 3.9e-39 133.6 0.2 6.5e-39 132.9 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EDO16920.1 - 2.5e-36 124.9 0.0 3.9e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain NAD_binding_10 PF13460.1 EDO16920.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Ribosomal_L23 PF00276.15 EDO16921.1 - 4.4e-21 74.6 1.1 4.4e-21 74.6 0.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 EDO16921.1 - 6.9e-21 74.0 9.0 6.9e-21 74.0 6.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain UPF0220 PF05255.6 EDO16922.1 - 9.5e-70 233.1 0.9 1.1e-69 232.9 0.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Glyco_hydro_72 PF03198.9 EDO16924.1 - 3.6e-130 433.5 2.6 4.6e-130 433.1 1.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase DNA_pol3_a_NII PF11490.3 EDO16924.1 - 0.031 13.8 0.5 0.11 12.1 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II PWWP PF00855.12 EDO16924.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 PWWP domain EOS1 PF12326.3 EDO16925.1 - 4.6e-70 234.0 7.6 4.6e-70 234.0 5.3 2.5 2 1 0 2 2 2 2 N-glycosylation protein DNA_mis_repair PF01119.14 EDO16926.1 - 1.1e-22 79.7 0.7 2.9e-22 78.3 0.1 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EDO16926.1 - 1.4e-22 79.8 0.0 2.8e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EDO16926.1 - 1.8e-12 47.0 0.6 1.8e-12 47.0 0.4 3.0 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO16926.1 - 5.4e-11 42.1 0.1 1.2e-10 41.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HORMA PF02301.13 EDO16927.1 - 2.3e-18 66.4 3.7 2.9e-18 66.1 2.6 1.1 1 0 0 1 1 1 1 HORMA domain Mito_carr PF00153.22 EDO16928.1 - 2.5e-62 206.6 5.7 9.3e-21 73.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EDO16928.1 - 3.2e-13 48.3 2.8 0.00011 21.7 0.1 4.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EDO16928.1 - 1.8e-12 47.1 6.3 7.7e-09 35.5 1.7 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EDO16928.1 - 1.1e-11 43.0 8.2 4.3e-05 22.5 0.2 4.6 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.1 EDO16928.1 - 1.6e-07 30.3 8.8 0.00015 20.9 0.6 3.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EDO16928.1 - 4.7e-06 26.1 6.1 0.019 14.5 0.9 3.7 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EDO16928.1 - 0.0088 16.0 12.2 0.32 11.0 0.3 3.3 1 1 2 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region 4HBT PF03061.17 EDO16929.1 - 0.00011 22.1 0.1 0.64 10.1 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily SKG6 PF08693.5 EDO16930.1 - 1.6e-12 46.4 0.4 4.1e-12 45.2 0.2 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain He_PIG PF05345.7 EDO16930.1 - 1.4e-10 40.9 10.9 6.3e-05 22.9 0.0 4.5 5 0 0 5 5 5 2 Putative Ig domain Mid2 PF04478.7 EDO16930.1 - 0.00083 18.8 3.8 0.0019 17.6 1.9 2.3 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor Rifin_STEVOR PF02009.11 EDO16930.1 - 0.0055 16.3 0.0 0.0093 15.6 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Adeno_E3_CR2 PF02439.10 EDO16930.1 - 0.017 14.6 0.3 0.027 14.0 0.2 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EDO16930.1 - 0.033 14.5 0.0 0.28 11.6 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cpn60_TCP1 PF00118.19 EDO16931.1 - 5.3e-139 463.9 12.1 6.3e-139 463.7 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transposase_23 PF03017.9 EDO16931.1 - 0.012 15.1 0.2 0.046 13.2 0.0 2.1 2 0 0 2 2 2 0 TNP1/EN/SPM transposase NAGLU_C PF12972.2 EDO16931.1 - 0.15 11.4 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain Snapin_Pallidin PF14712.1 EDO16932.1 - 4e-06 27.0 2.9 5e-06 26.7 2.0 1.1 1 0 0 1 1 1 1 Snapin/Pallidin MitMem_reg PF13012.1 EDO16932.1 - 0.052 13.6 1.5 0.07 13.2 1.1 1.2 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Spc24 PF08286.6 EDO16932.1 - 0.58 9.8 4.5 5 6.8 3.1 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 HALZ PF02183.13 EDO16932.1 - 1.2 8.8 7.1 13 5.5 0.1 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper zf-CCCH PF00642.19 EDO16933.1 - 0.00023 20.7 1.9 0.0016 18.0 0.1 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2183 PF09949.4 EDO16934.1 - 6.7e-33 112.6 1.4 3.5e-32 110.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Mem_trans PF03547.13 EDO16935.1 - 5.5e-86 288.2 0.0 3.8e-85 285.4 0.0 1.9 1 1 0 1 1 1 1 Membrane transport protein AMP-binding PF00501.23 EDO16936.1 - 2.5e-38 131.5 0.0 8.2e-17 60.6 0.0 5.1 5 0 0 5 5 5 5 AMP-binding enzyme DMAP_binding PF06464.6 EDO16936.1 - 2.4e-16 60.3 1.5 2.4e-16 60.3 1.0 3.5 2 1 1 3 3 3 1 DMAP1-binding Domain Arf PF00025.16 EDO16937.1 - 8.4e-72 240.0 0.2 9.5e-72 239.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDO16937.1 - 2.9e-14 52.7 0.0 3.4e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EDO16937.1 - 3.3e-14 52.4 0.0 4.1e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EDO16937.1 - 2.9e-13 49.2 1.6 4.5e-09 35.4 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDO16937.1 - 9.9e-11 41.2 0.0 1.2e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDO16937.1 - 9.9e-10 38.9 0.0 1.3e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDO16937.1 - 2.4e-06 27.4 0.0 3.2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EDO16937.1 - 0.088 11.8 0.1 0.17 10.9 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Rib_5-P_isom_A PF06026.9 EDO16938.1 - 8.8e-55 184.6 0.0 1.2e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EDO16938.1 - 0.0016 18.0 0.0 0.91 9.1 0.0 2.4 3 0 0 3 3 3 2 DeoR C terminal sensor domain Ribosomal_S7e PF01251.13 EDO16939.1 - 1.7e-82 275.5 2.5 2e-82 275.2 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF2345 PF10106.4 EDO16939.1 - 0.076 12.6 0.0 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2345) Alpha_kinase PF02816.13 EDO16940.1 - 0.013 15.1 0.2 0.016 14.8 0.1 1.1 1 0 0 1 1 1 0 Alpha-kinase family BacA PF02673.13 EDO16940.1 - 0.035 13.2 0.1 0.045 12.9 0.1 1.1 1 0 0 1 1 1 0 Bacitracin resistance protein BacA SPAN-X PF07458.7 EDO16940.1 - 0.2 11.9 2.2 0.31 11.3 1.5 1.2 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome Glyco_transf_15 PF01793.11 EDO16941.1 - 2.1e-144 480.5 15.5 2.5e-144 480.2 10.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 EDO16942.1 - 2.3e-143 477.1 17.3 2.9e-143 476.8 12.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CKS PF01111.14 EDO16942.1 - 0.055 13.2 1.7 0.24 11.2 1.2 2.1 1 0 0 1 1 1 0 Cyclin-dependent kinase regulatory subunit Mito_carr PF00153.22 EDO16943.1 - 4.3e-56 186.6 3.9 1.9e-20 72.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pentaxin PF00354.12 EDO16943.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Pentaxin family GIT_SHD PF08518.6 EDO16944.1 - 3.4e-23 80.6 4.9 1.9e-12 46.3 0.1 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT HSP70 PF00012.15 EDO16945.1 - 1.6e-271 901.5 10.7 1.8e-271 901.3 7.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO16945.1 - 3.2e-16 58.8 0.0 5e-15 54.9 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EDO16945.1 - 0.00043 19.2 0.6 0.0068 15.2 0.1 2.4 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EDO16945.1 - 0.0022 17.6 0.0 0.0078 15.8 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EDO16945.1 - 0.019 14.0 1.3 0.15 11.1 0.0 2.7 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase Mrr_N PF14338.1 EDO16945.1 - 0.095 12.7 0.6 1.4 9.0 0.3 2.4 2 0 0 2 2 2 0 Mrr N-terminal domain RRM_1 PF00076.17 EDO16947.1 - 9.5e-29 98.8 0.5 8.4e-20 70.1 0.0 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO16947.1 - 3.8e-23 81.2 0.4 4e-14 52.3 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO16947.1 - 6.5e-11 41.9 0.7 6.2e-08 32.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO16947.1 - 0.00047 19.8 0.0 0.00098 18.8 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif FAM150 PF15129.1 EDO16947.1 - 0.0013 18.5 0.6 0.0035 17.2 0.5 1.9 1 0 0 1 1 1 1 FAM150 family Seryl_tRNA_N PF02403.17 EDO16947.1 - 4.7 7.2 15.1 0.25 11.3 5.8 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Syndecan PF01034.15 EDO16948.1 - 0.001 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain Glycophorin_A PF01102.13 EDO16948.1 - 0.0055 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycophorin A Mid2 PF04478.7 EDO16948.1 - 0.033 13.5 0.3 0.085 12.2 0.1 1.8 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor DUF912 PF06024.7 EDO16948.1 - 0.16 12.0 0.0 0.16 12.0 0.0 2.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ras PF00071.17 EDO16949.1 - 9.1e-46 155.1 1.6 1.3e-45 154.6 0.0 1.8 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EDO16949.1 - 1.6e-16 60.9 0.0 2.1e-15 57.2 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDO16949.1 - 4e-05 22.9 0.0 6.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO16949.1 - 0.00011 21.7 0.0 0.00073 19.0 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO16949.1 - 0.0043 16.9 0.0 0.0093 15.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDO16949.1 - 0.0081 15.3 0.0 0.018 14.1 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EDO16949.1 - 0.018 14.2 0.1 0.24 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EDO16949.1 - 0.047 13.1 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RRM_1 PF00076.17 EDO16950.1 - 9.5e-06 25.1 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO16950.1 - 2e-05 24.4 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Cut12 PF11500.3 EDO16950.1 - 0.075 12.7 8.2 0.19 11.4 1.5 2.4 2 0 0 2 2 2 0 Spindle pole body formation-associated protein CENP-H PF05837.7 EDO16950.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Pkinase PF00069.20 EDO16951.1 - 2.9e-60 203.6 0.3 5.5e-60 202.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16951.1 - 7.4e-25 87.4 0.0 1.1e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO16951.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family ELFV_dehydrog PF00208.16 EDO16952.1 - 4e-57 193.5 0.0 7.1e-57 192.7 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EDO16952.1 - 2.1e-14 52.0 1.5 6e-10 37.2 0.1 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EDO16952.1 - 0.046 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain JAB PF01398.16 EDO16953.1 - 3.8e-25 87.8 0.6 8.7e-25 86.6 0.1 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EDO16953.1 - 9.6e-07 28.3 0.0 1.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Arm PF00514.18 EDO16955.1 - 4e-86 280.2 14.0 1.1e-12 47.2 0.1 8.7 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 EDO16955.1 - 1e-25 89.7 3.2 2.2e-25 88.6 2.2 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 EDO16955.1 - 1.5e-20 73.2 0.4 9.8e-06 25.7 0.0 5.4 1 1 4 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 EDO16955.1 - 6.4e-18 64.6 1.5 0.00012 22.4 0.0 5.9 3 2 3 6 6 6 4 HEAT-like repeat HEAT PF02985.17 EDO16955.1 - 1.3e-09 37.3 0.1 1.3 9.2 0.0 6.9 8 0 0 8 8 8 3 HEAT repeat Arm_2 PF04826.8 EDO16955.1 - 1.4e-07 30.9 0.8 0.68 8.9 0.0 4.9 2 2 2 5 5 5 3 Armadillo-like Proteasom_PSMB PF10508.4 EDO16955.1 - 3.6e-06 25.5 1.0 8.7e-05 20.9 0.2 2.6 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.15 EDO16955.1 - 2.7e-05 22.7 0.3 0.00017 20.0 0.1 2.3 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EDO16955.1 - 2.8e-05 24.0 0.4 0.17 11.8 0.0 4.4 3 2 2 5 5 5 1 V-ATPase subunit H MARVEL PF01284.18 EDO16956.1 - 6.9e-25 87.5 5.0 9.3e-25 87.1 3.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 EDO16956.1 - 4.3 6.8 8.4 1.2 8.7 2.8 2.0 2 0 0 2 2 2 0 SUR7/PalI family GATase_4 PF13230.1 EDO16957.1 - 2e-18 66.0 0.1 4e-17 61.8 0.1 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EDO16957.1 - 6.2e-11 42.3 0.0 1.8e-10 40.9 0.0 1.7 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EDO16957.1 - 2.2e-09 36.4 0.0 8.2e-08 31.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 EDO16957.1 - 0.0013 18.5 0.0 0.0037 16.9 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain Tyr_Deacylase PF02580.11 EDO16958.1 - 2.6e-48 163.6 0.1 2.9e-48 163.5 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF2167 PF09935.4 EDO16958.1 - 0.0056 15.5 0.0 0.0079 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2167) COX6B PF02297.12 EDO16960.1 - 3.4e-21 75.0 4.7 3.9e-21 74.8 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Somatostatin PF03002.10 EDO16960.1 - 0.005 16.4 0.4 0.012 15.2 0.3 1.7 1 0 0 1 1 1 1 Somatostatin/Cortistatin family APOBEC_C PF05240.9 EDO16960.1 - 0.045 13.1 0.6 0.061 12.7 0.4 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UPF0203 PF05254.7 EDO16960.1 - 0.35 10.7 5.4 2.1 8.2 1.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) RIC1 PF07064.8 EDO16961.1 - 3.8e-13 49.4 2.3 1.6e-12 47.4 1.6 1.9 1 1 0 1 1 1 1 RIC1 WD40 PF00400.27 EDO16962.1 - 6.4e-20 70.2 7.6 1.4e-07 31.1 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EDO16962.1 - 5.7e-18 64.5 0.1 1.6e-17 63.1 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF814 PF05670.8 EDO16963.1 - 1.5e-19 69.6 0.0 3.2e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Lipl32 PF12103.3 EDO16963.1 - 0.18 11.2 2.5 0.3 10.5 1.7 1.3 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order Trp_dioxygenase PF03301.8 EDO16963.1 - 0.34 9.9 5.4 0.51 9.3 1.4 2.0 2 0 0 2 2 2 0 Tryptophan 2,3-dioxygenase SEEEED PF14797.1 EDO16963.1 - 3 7.9 6.7 4.3 7.4 4.1 1.5 1 1 1 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Meiotic_rec114 PF03525.9 EDO16964.1 - 5.7e-15 54.6 16.5 9e-15 53.9 10.7 1.9 1 1 0 1 1 1 1 Meiotic recombination protein rec114 Nab1 PF04902.7 EDO16964.1 - 0.0045 16.4 0.2 0.0087 15.5 0.1 1.5 1 0 0 1 1 1 1 Conserved region in Nab1 VSP PF03302.8 EDO16964.1 - 0.47 9.0 1.8 0.64 8.5 1.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein SRP1_TIP1 PF00660.12 EDO16965.1 - 1.4e-09 37.7 0.9 3.6e-09 36.3 0.6 1.8 1 1 0 1 1 1 1 Seripauperin and TIP1 family Dala_Dala_lig_N PF01820.16 EDO16965.1 - 0.066 13.5 0.1 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus Golgin_A5 PF09787.4 EDO16965.1 - 1.6 7.1 13.1 3.8 5.9 9.1 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 CLTH PF10607.4 EDO16967.1 - 1.3e-22 80.0 24.9 3.4e-22 78.6 14.6 2.7 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain GATA PF00320.22 EDO16968.1 - 4.3e-16 57.9 2.3 8e-16 57.1 1.6 1.5 1 0 0 1 1 1 1 GATA zinc finger T4_baseplate PF12322.3 EDO16968.1 - 0.039 13.2 0.8 0.36 10.0 0.0 2.2 2 0 0 2 2 2 0 T4 bacteriophage base plate protein MyTH4 PF00784.12 EDO16968.1 - 0.086 12.7 0.3 0.19 11.6 0.1 1.7 2 0 0 2 2 2 0 MyTH4 domain TALPID3 PF15324.1 EDO16968.1 - 0.093 10.0 0.8 0.15 9.4 0.5 1.3 1 0 0 1 1 1 0 Hedgehog signalling target KKLCAg1 PF15204.1 EDO16968.1 - 0.13 12.2 0.9 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 Troponin-I_N PF11636.3 EDO16968.1 - 2.1 8.1 8.9 6.5 6.5 6.2 1.8 1 0 0 1 1 1 0 Troponin I residues 1-32 Arf PF00025.16 EDO16969.1 - 7.6e-33 113.2 0.0 9.6e-33 112.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDO16969.1 - 1.2e-08 34.4 0.0 2e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EDO16969.1 - 2.5e-07 31.2 0.0 3.1e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EDO16969.1 - 6.5e-07 28.3 0.1 0.011 14.4 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDO16969.1 - 6.9e-06 25.3 0.0 9.5e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO16969.1 - 5.9e-05 22.5 0.0 0.01 15.3 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO16969.1 - 0.00031 20.6 0.9 0.00047 20.1 0.6 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EDO16969.1 - 0.0019 17.4 0.0 0.0025 17.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EDO16969.1 - 0.051 12.8 0.2 0.86 8.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Ldh_1_N PF00056.18 EDO16970.1 - 4.5e-40 136.7 0.1 1e-39 135.5 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EDO16970.1 - 1.6e-27 96.3 0.0 2.7e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EDO16970.1 - 0.0004 19.1 0.0 0.0013 17.5 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EDO16970.1 - 0.034 14.4 0.0 0.076 13.3 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.20 EDO16971.1 - 1.2e-62 211.3 0.1 1.6e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16971.1 - 6.7e-26 90.9 0.0 9.6e-26 90.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO16971.1 - 0.013 15.2 0.1 0.088 12.5 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.1 EDO16972.1 - 0.66 9.7 6.4 1.4 8.6 4.4 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UPF0370 PF13980.1 EDO16972.1 - 4.2 7.2 7.2 17 5.3 0.3 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0370) Ribosomal_L13e PF01294.13 EDO16973.1 - 5e-72 241.1 5.6 6.8e-72 240.6 3.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_S9 PF00380.14 EDO16974.1 - 1e-38 132.2 0.2 1.2e-38 132.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DEAD PF00270.24 EDO16975.1 - 8.2e-35 119.7 0.2 2.4e-34 118.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO16975.1 - 3.4e-23 81.2 0.0 9.8e-22 76.6 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO16975.1 - 3.2e-05 23.8 0.1 0.00012 22.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HTH_psq PF05225.11 EDO16976.1 - 0.00032 20.1 0.0 0.00071 19.0 0.0 1.6 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_7 PF02796.10 EDO16976.1 - 0.11 12.3 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase HTH_Tnp_Tc5 PF03221.11 EDO16976.1 - 0.13 12.0 2.9 0.23 11.3 0.2 2.7 3 1 0 3 3 3 0 Tc5 transposase DNA-binding domain NUC153 PF08159.7 EDO16977.1 - 2e-13 49.6 5.2 4.3e-13 48.5 3.6 1.6 1 0 0 1 1 1 1 NUC153 domain Isochorismatase PF00857.15 EDO16978.1 - 3e-21 76.1 0.0 4e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DnaB_2 PF07261.6 EDO16978.1 - 0.08 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Replication initiation and membrane attachment HCaRG PF07258.9 EDO16978.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 HCaRG protein tRNA_bind PF01588.15 EDO16979.1 - 1.3e-19 69.8 0.2 1.9e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain DUF3336 PF11815.3 EDO16979.1 - 0.045 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) GreA_GreB PF01272.14 EDO16979.1 - 0.077 12.7 0.1 0.22 11.2 0.1 1.8 1 0 0 1 1 1 0 Transcription elongation factor, GreA/GreB, C-term PITH PF06201.8 EDO16980.1 - 2e-37 128.2 1.4 2.4e-37 128.0 0.9 1.1 1 0 0 1 1 1 1 PITH domain CSTF2_hinge PF14327.1 EDO16981.1 - 1.3e-25 89.2 1.2 1.3e-25 89.2 0.8 2.9 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 PAT1 PF09770.4 EDO16981.1 - 0.11 10.6 34.7 0.16 10.1 24.1 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PEMT PF04191.8 EDO16982.1 - 3.8e-59 197.3 10.1 5.5e-34 116.4 1.5 2.8 2 0 0 2 2 2 2 Phospholipid methyltransferase AAA PF00004.24 EDO16984.1 - 1.9e-43 147.7 0.0 3.8e-43 146.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO16984.1 - 5.9e-07 29.2 0.0 5.7e-06 26.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDO16984.1 - 7.1e-07 29.3 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EDO16984.1 - 4.5e-06 26.8 0.0 0.0003 20.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO16984.1 - 2.3e-05 24.4 0.0 0.0001 22.3 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDO16984.1 - 4.2e-05 24.3 0.3 0.00014 22.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO16984.1 - 0.00013 21.6 0.1 0.00031 20.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EDO16984.1 - 0.00015 20.9 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EDO16984.1 - 0.00023 20.6 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EDO16984.1 - 0.00067 19.5 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EDO16984.1 - 0.0018 18.2 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EDO16984.1 - 0.0019 18.1 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDO16984.1 - 0.003 16.6 0.0 0.0067 15.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EDO16984.1 - 0.0052 16.3 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2072 PF09845.4 EDO16984.1 - 0.007 16.2 0.7 0.015 15.2 0.5 1.6 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) Mg_chelatase PF01078.16 EDO16984.1 - 0.0089 15.2 0.2 0.025 13.7 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EDO16984.1 - 0.0096 16.2 1.5 0.031 14.5 0.0 2.6 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 EDO16984.1 - 0.01 14.5 0.0 0.022 13.4 0.0 1.6 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 EDO16984.1 - 0.013 14.7 0.0 0.045 12.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 EDO16984.1 - 0.026 13.9 0.1 0.1 12.0 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EDO16984.1 - 0.026 14.0 0.0 0.15 11.5 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.1 EDO16984.1 - 0.03 13.9 0.0 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDO16984.1 - 0.032 14.4 0.0 0.076 13.1 0.0 1.7 1 1 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EDO16984.1 - 0.063 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EDO16984.1 - 0.072 12.7 0.0 0.35 10.5 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF815 PF05673.8 EDO16984.1 - 0.075 11.9 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EDO16984.1 - 0.087 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MIF4G PF02854.14 EDO16985.1 - 2.6e-47 160.9 0.2 5e-47 160.0 0.1 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EDO16985.1 - 1e-27 95.7 0.8 1e-27 95.7 0.5 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 DUF1574 PF07611.6 EDO16985.1 - 0.036 12.9 0.1 0.036 12.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1574) Cys_Met_Meta_PP PF01053.15 EDO16986.1 - 8.2e-146 485.2 0.0 9.3e-146 485.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EDO16986.1 - 1.3e-13 50.7 0.0 2.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EDO16986.1 - 4.6e-11 42.0 0.1 6.9e-11 41.4 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EDO16986.1 - 1.8e-10 40.2 0.0 2.8e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EDO16986.1 - 4.4e-06 26.0 0.0 8.4e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 EDO16986.1 - 0.0063 14.8 0.1 0.011 14.0 0.1 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 EDO16986.1 - 0.017 13.8 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein ABC_membrane PF00664.18 EDO16987.1 - 8.5e-54 182.8 45.5 3.9e-34 118.3 9.6 2.8 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDO16987.1 - 8.5e-52 175.0 0.3 2.1e-29 102.5 0.2 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDO16987.1 - 2.1e-07 30.4 15.9 0.00069 18.9 0.6 4.3 3 2 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDO16987.1 - 2.1e-07 30.3 0.1 0.017 14.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EDO16987.1 - 3.3e-07 30.4 1.1 0.027 14.4 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 EDO16987.1 - 6.1e-06 25.8 0.2 0.007 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 EDO16987.1 - 1.2e-05 25.4 0.6 0.046 13.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EDO16987.1 - 1.2e-05 24.3 0.3 0.032 13.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EDO16987.1 - 2.5e-05 25.1 1.1 0.16 12.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EDO16987.1 - 2.7e-05 24.1 0.5 0.16 11.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EDO16987.1 - 9.6e-05 21.8 0.0 0.38 10.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EDO16987.1 - 0.00059 18.7 1.9 1.5 7.6 0.0 3.5 4 0 0 4 4 4 2 NB-ARC domain AAA_23 PF13476.1 EDO16987.1 - 0.0013 19.0 17.6 0.0031 17.8 3.6 3.5 3 2 0 3 3 2 1 AAA domain MobB PF03205.9 EDO16987.1 - 0.0016 18.1 1.6 1.2 8.8 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EDO16987.1 - 0.0033 16.6 0.0 2.5 7.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EDO16987.1 - 0.0037 16.7 0.1 3.8 6.9 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 EDO16987.1 - 0.0045 17.3 4.7 1 9.6 0.0 3.7 4 0 0 4 4 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EDO16987.1 - 0.0055 16.1 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EDO16987.1 - 0.0062 17.0 0.8 4.6 7.7 0.0 3.1 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 EDO16987.1 - 0.0063 16.1 1.8 2.1 7.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain TrwB_AAD_bind PF10412.4 EDO16987.1 - 0.0082 14.8 0.2 3 6.3 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 EDO16987.1 - 0.014 15.2 0.0 1 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EDO16987.1 - 0.045 13.3 0.2 0.76 9.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EDO16987.1 - 0.047 12.7 0.1 9.6 5.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.4 EDO16987.1 - 0.053 12.1 3.9 0.13 10.8 0.0 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class cobW PF02492.14 EDO16987.1 - 0.053 12.9 0.1 0.053 12.9 0.1 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Dynamin_N PF00350.18 EDO16987.1 - 0.059 13.1 4.7 5.5 6.7 0.0 3.6 3 0 0 3 3 3 0 Dynamin family PduV-EutP PF10662.4 EDO16987.1 - 0.061 12.8 1.0 4.8 6.6 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EDO16987.1 - 0.079 12.6 2.0 0.5 10.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain ArgK PF03308.11 EDO16987.1 - 0.14 10.9 0.3 0.38 9.4 0.0 1.8 2 0 0 2 2 2 0 ArgK protein AAA_19 PF13245.1 EDO16987.1 - 0.19 11.5 0.3 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EDO16987.1 - 0.65 10.1 4.8 3 8.0 0.3 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EDO16987.1 - 0.98 9.1 5.9 13 5.4 0.2 3.0 3 0 0 3 3 3 0 NTPase Peptidase_S10 PF00450.17 EDO16988.1 - 3.8e-98 329.3 0.2 4.5e-98 329.1 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase SAPS PF04499.10 EDO16988.1 - 4.6 5.7 13.3 8.1 4.9 9.2 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein UPF0113 PF03657.8 EDO16989.1 - 5.6e-14 52.1 0.0 7.2e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EDO16989.1 - 0.041 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 PUA domain SRP72 PF08492.7 EDO16990.1 - 7.7e-11 42.2 5.0 7.7e-11 42.2 3.5 2.5 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_12 PF13424.1 EDO16990.1 - 6.3e-07 29.2 7.2 0.00071 19.4 0.4 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO16990.1 - 9.3e-06 25.1 2.6 3.2 7.9 0.0 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDO16990.1 - 1.8e-05 24.9 5.4 0.17 12.2 0.4 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO16990.1 - 0.0015 18.5 16.3 5.1 7.3 0.8 5.2 3 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EDO16990.1 - 0.0016 18.0 0.1 8 6.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO16990.1 - 0.004 17.5 2.2 92 3.8 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDO16990.1 - 0.0056 16.3 5.7 0.042 13.6 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO16990.1 - 0.017 14.7 1.1 29 4.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 EDO16990.1 - 0.045 13.7 0.0 43 4.3 0.0 3.9 4 0 0 4 4 4 0 PPR repeat DUF448 PF04296.8 EDO16990.1 - 0.095 12.3 0.7 0.58 9.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF448) Pkinase PF00069.20 EDO16991.1 - 8.3e-76 254.5 0.2 1.2e-75 254.0 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO16991.1 - 6.5e-47 159.7 0.0 8.8e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO16991.1 - 4.9e-06 25.7 0.0 1.4e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EDO16991.1 - 0.00035 19.9 0.5 0.0014 18.0 0.0 1.9 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.9 EDO16991.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DASH_Spc19 PF08287.6 EDO16991.1 - 0.24 11.0 2.3 0.44 10.1 1.6 1.4 1 0 0 1 1 1 0 Spc19 Pkinase PF00069.20 EDO16993.1 - 1.5e-07 30.8 0.0 2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain HLH PF00010.21 EDO16994.1 - 9.4e-23 79.6 0.2 2.8e-22 78.1 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SOBP PF15279.1 EDO16994.1 - 0.04 14.3 5.2 0.054 13.8 3.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein TGS PF02824.16 EDO16995.1 - 2.9e-22 78.2 0.1 5.2e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EDO16995.1 - 4.3e-17 62.1 0.1 1e-16 60.9 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO16995.1 - 5.7e-09 35.4 0.1 1.5e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EDO16995.1 - 0.00091 19.0 0.4 0.64 9.8 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EDO16995.1 - 0.0061 15.3 0.1 0.012 14.4 0.1 1.5 1 0 0 1 1 1 1 ArgK protein Miro PF08477.8 EDO16995.1 - 0.011 16.2 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 EDO16995.1 - 0.11 11.7 0.1 2 7.6 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family Mis12 PF05859.7 EDO16996.1 - 2.5e-44 150.5 3.7 2.5e-44 150.5 2.6 1.8 2 0 0 2 2 2 1 Mis12 protein GvpK PF05121.7 EDO16996.1 - 1.7 8.4 7.3 1.1 9.1 0.8 2.8 3 0 0 3 3 3 0 Gas vesicle protein K UQ_con PF00179.21 EDO16997.1 - 1.1e-47 160.9 0.0 1.3e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDO16997.1 - 0.002 17.9 0.3 0.0039 17.0 0.2 1.8 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EDO16997.1 - 0.0021 17.7 0.2 0.0036 16.9 0.1 1.4 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 EDO16997.1 - 0.0034 17.1 0.0 0.0049 16.6 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B AA_permease PF00324.16 EDO16998.1 - 4.9e-123 410.9 36.9 6.1e-123 410.6 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO16998.1 - 6.2e-33 113.9 35.2 8e-33 113.5 24.4 1.1 1 0 0 1 1 1 1 Amino acid permease ROK PF00480.15 EDO16998.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 ROK family TFIIS_C PF01096.13 EDO16999.1 - 2.5e-21 75.0 1.6 2.5e-21 75.0 1.1 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EDO16999.1 - 2.3e-13 49.5 1.0 2.3e-13 49.5 0.7 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 EDO16999.1 - 0.0096 15.6 2.5 0.12 12.0 0.1 2.3 2 1 0 2 2 2 1 Transcription elongation factor Elf1 like Terminase_GpA PF05876.7 EDO16999.1 - 0.038 12.3 1.1 0.78 8.0 0.8 2.0 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) zf-piccolo PF05715.8 EDO16999.1 - 0.055 13.4 0.4 0.055 13.4 0.3 2.4 3 0 0 3 3 3 0 Piccolo Zn-finger DUF2387 PF09526.5 EDO16999.1 - 0.11 12.3 2.5 2.6 8.0 0.1 2.3 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Zn_Tnp_IS1595 PF12760.2 EDO16999.1 - 0.12 12.1 3.6 1.6 8.5 0.2 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.3 EDO16999.1 - 0.32 10.4 0.1 0.32 10.4 0.1 2.2 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Desulfoferrod_N PF06397.7 EDO16999.1 - 0.37 10.2 0.2 0.37 10.2 0.1 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Lar_restr_allev PF14354.1 EDO16999.1 - 0.51 10.6 4.3 20 5.5 3.0 2.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar PhnA_Zn_Ribbon PF08274.7 EDO16999.1 - 0.91 9.3 8.3 2.8 7.8 0.3 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DZR PF12773.2 EDO16999.1 - 2.5 7.9 6.4 5.6 6.8 0.2 2.7 2 2 0 2 2 2 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 EDO16999.1 - 3.5 7.2 10.2 17 5.1 0.4 3.8 4 0 0 4 4 4 0 zinc-ribbon domain IBR PF01485.16 EDO16999.1 - 4.4 7.2 7.7 8.6 6.3 0.1 3.0 2 1 0 2 2 2 0 IBR domain Zn-ribbon_8 PF09723.5 EDO16999.1 - 6.7 6.7 7.7 24 4.9 0.1 3.6 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2H2 PF00096.21 EDO17000.1 - 6.8e-08 32.4 12.1 4.7e-05 23.4 2.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO17000.1 - 1.4e-07 31.4 17.0 3e-06 27.2 1.7 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO17000.1 - 0.00016 21.7 8.9 0.09 13.1 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EDO17000.1 - 0.082 12.5 1.1 0.16 11.6 0.8 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-met PF12874.2 EDO17000.1 - 0.1 12.8 0.5 0.1 12.8 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn_Tnp_IS1595 PF12760.2 EDO17000.1 - 0.12 12.2 0.7 0.12 12.2 0.5 1.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_jaz PF12171.3 EDO17000.1 - 0.19 11.9 0.1 0.19 11.9 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EDO17000.1 - 0.71 9.6 11.3 1.8 8.3 3.3 2.5 1 1 1 2 2 2 0 BED zinc finger ComA PF02679.10 EDO17001.1 - 0.0015 17.5 0.1 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Spermine_synth PF01564.12 EDO17002.1 - 1.2e-100 335.4 0.0 1.5e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EDO17002.1 - 0.00075 19.1 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO17002.1 - 0.0087 16.5 0.1 0.035 14.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 EDO17002.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF43 Methyltransf_18 PF12847.2 EDO17002.1 - 0.02 15.4 0.0 0.039 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF226 PF02890.9 EDO17002.1 - 0.036 13.8 0.1 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 Methyltransf_23 PF13489.1 EDO17002.1 - 0.069 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_trans_1_4 PF13692.1 EDO17003.1 - 1.1e-13 51.5 0.0 2.8e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EDO17003.1 - 5.8e-11 42.1 0.0 9.2e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EDO17003.1 - 5.3e-05 23.4 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sarcoglycan_1 PF04790.8 EDO17003.1 - 0.16 11.1 0.9 0.28 10.3 0.6 1.3 1 0 0 1 1 1 0 Sarcoglycan complex subunit protein CENP-L PF13092.1 EDO17004.1 - 0.0083 15.9 0.2 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Fe-S_biosyn PF01521.15 EDO17005.1 - 2.4e-11 43.5 0.4 5.6e-05 23.0 0.0 2.4 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis ThiF PF00899.16 EDO17006.1 - 3.3e-31 107.9 0.0 6.1e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EDO17006.1 - 2.6e-20 71.7 1.7 1.6e-19 69.2 0.3 2.5 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EDO17006.1 - 3.6e-09 35.8 2.2 4.6e-09 35.5 0.5 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site TrkA_N PF02254.13 EDO17006.1 - 0.001 19.0 0.4 0.54 10.2 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Shikimate_DH PF01488.15 EDO17006.1 - 0.1 12.6 0.1 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pho88 PF10032.4 EDO17007.1 - 1.2e-83 279.1 1.6 1.3e-83 278.9 1.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Vac_ImportDeg PF09783.4 EDO17008.1 - 2.9e-60 202.7 2.9 4.2e-60 202.2 2.0 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein bPH_3 PF14470.1 EDO17008.1 - 0.066 13.4 0.2 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial PH domain UPF0139 PF03669.8 EDO17009.1 - 0.00013 21.4 0.3 0.00027 20.3 0.2 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) Nt_Gln_amidase PF09764.4 EDO17009.1 - 0.035 13.3 0.1 0.055 12.7 0.0 1.3 1 1 0 1 1 1 0 N-terminal glutamine amidase FA_desaturase PF00487.19 EDO17009.1 - 0.097 12.0 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase dCMP_cyt_deam_1 PF00383.17 EDO17010.1 - 1.7e-22 78.9 0.0 2.3e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EDO17010.1 - 0.0012 18.7 0.2 0.0054 16.5 0.1 2.0 1 1 1 2 2 2 1 Bd3614-like deaminase XOO_2897-deam PF14440.1 EDO17010.1 - 0.013 15.1 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Mito_carr PF00153.22 EDO17011.1 - 3.5e-56 186.8 3.7 6e-21 73.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CytB6-F_Fe-S PF08802.5 EDO17011.1 - 0.12 12.3 0.4 0.42 10.6 0.3 2.0 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit IFN-gamma PF00714.12 EDO17012.1 - 0.081 12.7 0.1 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Interferon gamma zf-C2H2_4 PF13894.1 EDO17012.1 - 0.48 10.8 14.8 0.51 10.7 0.2 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO17012.1 - 8.6 6.6 11.6 4.1 7.6 0.2 3.7 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Tfb4 PF03850.9 EDO17013.1 - 0.011 14.9 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 WD40 PF00400.27 EDO17014.1 - 3.6e-28 96.3 14.9 3.2e-06 26.8 1.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat LisH PF08513.6 EDO17014.1 - 7.2e-09 35.1 0.1 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 LisH BBS2_Mid PF14783.1 EDO17014.1 - 1.7e-05 24.5 0.2 0.65 9.7 0.0 4.3 2 2 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EDO17014.1 - 0.00033 20.4 2.2 0.13 12.0 0.1 3.8 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.1 EDO17014.1 - 0.0007 18.7 0.0 0.003 16.6 0.0 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Vps16_N PF04841.8 EDO17014.1 - 0.0033 16.0 0.1 0.053 12.0 0.0 2.5 2 1 1 3 3 3 1 Vps16, N-terminal region Vps51 PF08700.6 EDO17015.1 - 2.5e-08 33.6 0.6 2.5e-08 33.6 0.4 3.3 3 1 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.6 EDO17015.1 - 0.0015 18.4 8.6 0.0047 16.7 0.9 3.0 2 0 0 2 2 2 2 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.20 EDO17016.1 - 5.6e-21 74.8 6.6 5.6e-20 71.5 4.6 2.6 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EDO17016.1 - 6.9e-12 44.3 6.0 0.031 14.3 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat Pkinase_Tyr PF07714.12 EDO17016.1 - 8.8e-08 31.5 0.5 0.0002 20.5 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_2 PF13646.1 EDO17016.1 - 3.8e-06 27.0 0.0 0.022 15.0 0.0 3.5 2 2 2 4 4 4 3 HEAT repeats DUF4557 PF15101.1 EDO17016.1 - 0.21 11.4 17.1 0.011 15.5 7.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4557) Pex14_N PF04695.8 EDO17016.1 - 0.65 10.0 16.9 1.9 8.5 11.7 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 4HBT_2 PF13279.1 EDO17017.1 - 8.8e-10 39.0 0.0 1.2e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily HMG_box PF00505.14 EDO17018.1 - 1.4e-25 89.3 0.7 2.1e-25 88.7 0.5 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO17018.1 - 1e-18 67.4 1.0 1.5e-18 66.9 0.7 1.2 1 0 0 1 1 1 1 HMG-box domain YABBY PF04690.8 EDO17018.1 - 0.0062 16.8 0.3 0.0081 16.4 0.1 1.3 1 1 0 1 1 1 1 YABBY protein CHDNT PF08073.7 EDO17018.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 CHDNT (NUC034) domain HMG_box_5 PF14887.1 EDO17018.1 - 0.012 15.4 4.1 0.013 15.2 2.4 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box 5 DUF1014 PF06244.7 EDO17018.1 - 0.016 15.3 0.1 0.032 14.4 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) SR-25 PF10500.4 EDO17018.1 - 0.27 10.6 3.1 0.34 10.3 2.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Acetyltransf_1 PF00583.19 EDO17019.1 - 7e-19 67.6 0.0 1e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO17019.1 - 2.4e-10 40.4 0.0 3.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDO17019.1 - 1.2e-09 37.8 0.1 1.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EDO17019.1 - 9e-09 35.3 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO17019.1 - 3.9e-07 30.1 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDO17019.1 - 2.5e-06 27.6 0.0 2.9e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO17019.1 - 0.00019 21.2 0.0 0.00046 20.0 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDO17019.1 - 0.0031 17.4 0.2 0.0035 17.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF444 PF04285.7 EDO17019.1 - 0.034 12.7 0.1 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Acetyltransf_CG PF14542.1 EDO17019.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase ATG11 PF10377.4 EDO17020.1 - 1.1e-40 138.5 0.2 1.1e-40 138.5 0.1 2.9 3 0 0 3 3 3 1 Autophagy-related protein 11 DUF904 PF06005.7 EDO17020.1 - 0.0047 17.1 7.3 0.0047 17.1 5.1 6.9 5 1 1 6 6 6 2 Protein of unknown function (DUF904) DUF4639 PF15479.1 EDO17020.1 - 3.6 6.1 19.2 5.9 5.4 13.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) Adaptin_N PF01602.15 EDO17021.1 - 5.6e-106 354.9 28.6 7.1e-106 354.6 19.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EDO17021.1 - 1.1e-07 31.8 0.0 2.6e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Rubredoxin PF00301.15 EDO17023.1 - 0.00048 19.9 3.1 0.14 12.0 0.2 2.7 2 0 0 2 2 2 2 Rubredoxin zf-RING_5 PF14634.1 EDO17023.1 - 0.066 12.9 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Cys_rich_KTR PF14205.1 EDO17023.1 - 0.11 11.9 1.3 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 Cysteine-rich KTR Androgen_recep PF02166.11 EDO17023.1 - 0.22 10.3 3.0 0.26 10.1 2.1 1.1 1 0 0 1 1 1 0 Androgen receptor Ribosomal_L19e PF01280.15 EDO17024.1 - 1.8e-59 199.7 10.8 1.8e-59 199.7 7.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e TEA PF01285.13 EDO17025.1 - 1.6e-31 109.9 6.9 1.6e-31 109.9 4.8 3.9 1 1 0 3 3 3 1 TEA/ATTS domain family PRKCSH PF07915.8 EDO17026.1 - 4e-11 43.5 1.0 9.9e-11 42.3 0.7 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EDO17026.1 - 0.00025 20.5 2.3 0.00043 19.7 1.0 1.9 1 1 1 2 2 2 1 Glucosidase II beta subunit-like protein PCI PF01399.22 EDO17027.1 - 1e-05 25.8 4.8 2e-05 24.8 0.1 3.1 2 1 0 2 2 2 1 PCI domain UQ_con PF00179.21 EDO17028.1 - 1.5e-44 150.7 0.1 2.4e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EDO17028.1 - 0.00077 19.2 0.0 0.0034 17.1 0.0 2.0 1 1 0 1 1 1 1 Prokaryotic E2 family B AMNp_N PF10423.4 EDO17028.1 - 0.16 11.4 1.0 0.31 10.6 0.1 1.8 1 1 1 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus Hyccin PF09790.4 EDO17029.1 - 0.08 11.7 0.1 0.13 11.0 0.1 1.4 1 1 0 1 1 1 0 Hyccin Dfp1_Him1_M PF08630.5 EDO17030.1 - 4.9e-46 155.5 2.9 1.8e-45 153.7 0.1 2.9 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 EDO17030.1 - 2.7e-21 74.9 0.4 5.2e-21 74.0 0.3 1.5 1 0 0 1 1 1 1 DBF zinc finger DUF2175 PF09943.4 EDO17030.1 - 5.9 7.0 8.1 0.67 10.0 0.3 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C2H2 PF00096.21 EDO17031.1 - 1.2e-11 44.2 7.4 5.2e-06 26.4 0.6 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO17031.1 - 2.6e-07 30.5 11.6 9.5e-06 25.6 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EDO17031.1 - 2.4e-05 24.3 3.9 0.00079 19.5 0.3 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EDO17031.1 - 0.00011 22.3 5.5 0.019 15.2 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger SprT-like PF10263.4 EDO17031.1 - 0.01 15.4 1.0 0.017 14.7 0.7 1.3 1 0 0 1 1 1 0 SprT-like family zf-C2H2_jaz PF12171.3 EDO17031.1 - 0.03 14.4 0.1 0.03 14.4 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EDO17031.1 - 4.7 7.6 5.6 13 6.2 0.1 3.2 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DUF2457 PF10446.4 EDO17032.1 - 0.19 10.4 6.8 0.28 9.8 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EDO17032.1 - 9.9 5.6 8.1 19 4.7 5.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Septin PF00735.13 EDO17033.1 - 1.8e-112 374.9 1.1 3.2e-112 374.1 0.7 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EDO17033.1 - 2.3e-06 27.5 0.1 4.8e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDO17033.1 - 9.2e-06 24.9 0.6 3.4e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EDO17033.1 - 4.3e-05 23.0 0.1 0.00087 18.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EDO17033.1 - 0.00042 20.4 0.0 0.0014 18.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EDO17033.1 - 0.00076 19.9 0.0 0.0042 17.5 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein IIGP PF05049.8 EDO17033.1 - 0.0035 16.2 0.0 0.0084 14.9 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EDO17033.1 - 0.0035 16.8 0.0 0.0068 15.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EDO17033.1 - 0.0036 17.1 5.1 0.67 9.7 0.0 3.3 2 1 1 3 3 3 1 Dynamin family Gtr1_RagA PF04670.7 EDO17033.1 - 0.0044 16.1 0.2 0.02 14.0 0.1 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AIG1 PF04548.11 EDO17033.1 - 0.011 14.8 0.1 0.011 14.8 0.1 2.0 2 0 0 2 2 2 0 AIG1 family RNA_helicase PF00910.17 EDO17033.1 - 0.018 15.1 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 EDO17033.1 - 0.024 13.9 0.0 0.054 12.7 0.0 1.6 1 0 0 1 1 1 0 Poxvirus A32 protein NACHT PF05729.7 EDO17033.1 - 0.027 14.1 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EDO17033.1 - 0.029 13.8 0.0 0.06 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 EDO17033.1 - 0.031 13.7 0.1 0.073 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 EDO17033.1 - 0.033 13.7 0.2 0.068 12.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EDO17033.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain ArgK PF03308.11 EDO17033.1 - 0.065 11.9 0.5 17 4.1 0.0 3.0 3 0 0 3 3 3 0 ArgK protein MobB PF03205.9 EDO17033.1 - 0.081 12.6 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EDO17033.1 - 0.11 12.7 0.2 0.11 12.7 0.1 2.1 2 1 0 2 2 2 0 ABC transporter KAP_NTPase PF07693.9 EDO17033.1 - 0.26 10.2 4.0 0.12 11.2 0.9 1.9 1 1 1 2 2 2 0 KAP family P-loop domain PduV-EutP PF10662.4 EDO17033.1 - 0.26 10.7 2.2 0.79 9.2 0.3 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pyr_redox_2 PF07992.9 EDO17034.1 - 9.5e-27 94.1 0.0 1.9e-26 93.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO17034.1 - 9.4e-18 64.4 0.2 8.2e-15 54.9 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO17034.1 - 4.3e-09 36.7 0.0 1.6e-06 28.3 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDO17034.1 - 0.00039 19.3 3.6 1.2 7.8 0.0 4.3 3 1 1 5 5 5 2 Glucose inhibited division protein A K_oxygenase PF13434.1 EDO17034.1 - 0.00083 18.3 0.0 0.38 9.6 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EDO17034.1 - 0.0024 18.0 0.0 0.14 12.4 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EDO17034.1 - 0.0054 16.7 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EDO17034.1 - 0.0086 16.1 0.1 1.3 9.1 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EDO17034.1 - 0.012 14.7 0.0 0.13 11.2 0.0 2.3 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EDO17034.1 - 0.031 13.1 0.6 0.95 8.2 0.1 2.7 2 2 1 3 3 3 0 FAD binding domain HI0933_like PF03486.9 EDO17034.1 - 0.033 12.6 0.1 7.4 4.9 0.0 2.8 2 1 1 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.14 EDO17034.1 - 0.07 12.1 0.0 8.1 5.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 EDO17034.1 - 0.096 12.4 0.1 10 5.8 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PX PF00787.19 EDO17035.1 - 6.3e-15 54.9 0.0 8.1e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 PX domain DNA_ligase_A_M PF01068.16 EDO17035.1 - 0.0097 15.2 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain PQ-loop PF04193.9 EDO17036.1 - 1.4e-37 127.0 7.5 2.3e-18 65.4 1.1 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EDO17036.1 - 0.00022 21.0 5.4 0.1 12.4 0.1 3.3 2 1 1 3 3 3 3 Sugar efflux transporter for intercellular exchange PGP_phosphatase PF09419.5 EDO17038.1 - 8.3e-70 233.5 0.0 9.5e-70 233.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EDO17038.1 - 0.00081 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDO17038.1 - 0.074 13.4 0.0 1.6 9.0 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase YEATS PF03366.11 EDO17039.1 - 2e-24 85.1 0.1 3.3e-24 84.4 0.1 1.4 1 0 0 1 1 1 1 YEATS family Nop14 PF04147.7 EDO17039.1 - 0.095 10.6 0.1 0.12 10.3 0.1 1.1 1 0 0 1 1 1 0 Nop14-like family YEATS PF03366.11 EDO17040.1 - 3.6e-22 77.8 2.2 6.3e-22 77.1 0.0 2.4 3 0 0 3 3 3 1 YEATS family TRF PF08558.5 EDO17041.1 - 6e-70 235.3 11.2 9e-70 234.7 7.8 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EDO17041.1 - 1.7e-07 31.2 0.2 3.3e-07 30.2 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO17041.1 - 0.003 17.6 0.0 0.0085 16.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain IBN_N PF03810.14 EDO17042.1 - 5.6e-15 55.0 0.9 2.5e-14 52.9 0.6 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRISPR_Cse2 PF09485.5 EDO17042.1 - 0.14 12.2 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) PspA_IM30 PF04012.7 EDO17043.1 - 0.077 12.3 0.5 0.077 12.3 0.4 1.7 2 0 0 2 2 2 0 PspA/IM30 family Enkurin PF13864.1 EDO17043.1 - 0.53 10.5 4.3 1.5 9.0 0.5 2.7 2 0 0 2 2 2 0 Calmodulin-binding IncA PF04156.9 EDO17043.1 - 0.74 9.3 3.8 1.3 8.6 0.2 2.2 2 0 0 2 2 2 0 IncA protein DUF342 PF03961.8 EDO17043.1 - 1 7.6 4.6 4.4 5.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Striatin PF08232.7 EDO17043.1 - 4.8 7.5 11.7 1.7 8.9 2.9 2.6 1 1 1 2 2 2 0 Striatin family Ribonuclease_T2 PF00445.13 EDO17044.1 - 1.9e-42 145.0 0.3 3.3e-42 144.2 0.2 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Sec61_beta PF03911.11 EDO17045.1 - 1.1e-16 60.3 0.9 1.3e-16 60.0 0.6 1.1 1 0 0 1 1 1 1 Sec61beta family PALP PF00291.20 EDO17046.1 - 5.2e-73 245.9 0.2 7.1e-73 245.4 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EDO17046.1 - 4.7e-43 144.6 0.1 3.5e-29 100.2 0.0 2.6 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase MMR1 PF08505.5 EDO17047.1 - 8.4e-82 274.7 22.2 8.4e-82 274.7 15.4 2.5 2 1 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein MipA PF06629.7 EDO17047.1 - 0.019 14.3 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 MltA-interacting protein MipA Peroxin-13_N PF04088.8 EDO17048.1 - 7.2e-56 188.5 0.9 1.1e-55 187.8 0.6 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EDO17048.1 - 2e-09 36.8 0.0 4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDO17048.1 - 9e-09 34.5 0.0 1.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO17048.1 - 2.6e-08 33.3 0.1 1e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 EDO17048.1 - 0.00018 21.6 0.1 0.00031 20.8 0.1 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain FAD-oxidase_C PF02913.14 EDO17049.1 - 3e-57 193.8 0.0 3.6e-56 190.2 0.0 2.0 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EDO17049.1 - 9.8e-35 119.0 0.0 1.8e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DUF3602 PF12223.3 EDO17050.1 - 4.8e-12 46.0 7.5 2.4e-10 40.6 1.0 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF1633 PF07794.6 EDO17050.1 - 0.13 10.1 3.3 0.16 9.9 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Glu_synthase PF01645.12 EDO17051.1 - 3e-154 513.3 0.0 5.3e-154 512.5 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EDO17051.1 - 8.5e-137 455.6 0.0 2e-136 454.4 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EDO17051.1 - 8.8e-117 389.4 0.0 6.3e-116 386.6 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 EDO17051.1 - 1.3e-59 200.5 1.3 2.4e-59 199.7 0.9 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EDO17051.1 - 2.6e-24 84.9 0.1 5.4e-24 83.9 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EDO17051.1 - 2.2e-15 57.0 0.0 8e-15 55.2 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO17051.1 - 1.4e-09 38.3 0.3 0.00026 21.1 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO17051.1 - 6e-09 35.8 0.0 1.6e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EDO17051.1 - 9e-09 35.6 0.1 1.8e-05 25.0 0.0 3.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EDO17051.1 - 6.8e-06 25.4 0.1 1.7e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EDO17051.1 - 4.2e-05 22.6 0.1 4.2e-05 22.6 0.1 2.3 3 0 0 3 3 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EDO17051.1 - 4.7e-05 22.0 0.1 4.7e-05 22.0 0.1 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.19 EDO17051.1 - 0.00025 20.0 0.0 0.00048 19.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EDO17051.1 - 0.002 17.2 0.0 0.0062 15.6 0.0 1.8 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.1 EDO17051.1 - 0.0039 17.4 1.4 1.1 9.5 0.0 3.2 3 0 0 3 3 2 1 Putative NAD(P)-binding GATase_6 PF13522.1 EDO17051.1 - 0.005 16.8 0.0 0.028 14.3 0.0 2.2 1 1 1 2 2 2 1 Glutamine amidotransferase domain FAD_oxidored PF12831.2 EDO17051.1 - 0.0054 15.8 0.5 0.009 15.1 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EDO17051.1 - 0.011 15.4 0.0 0.032 13.9 0.0 1.9 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 EDO17051.1 - 0.016 14.2 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EDO17051.1 - 0.018 13.9 1.6 0.097 11.5 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EDO17051.1 - 0.022 14.3 0.0 3.2 7.2 0.0 2.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.12 EDO17051.1 - 0.026 14.9 0.0 0.42 11.0 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EDO17051.1 - 0.047 13.1 0.0 0.16 11.3 0.0 2.0 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EDO17051.1 - 0.058 12.5 0.0 3.8 6.6 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EDO17051.1 - 0.062 13.0 0.0 0.38 10.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding IlvN PF07991.7 EDO17051.1 - 0.064 12.6 0.8 0.61 9.4 0.0 2.7 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain YjeF_N PF03853.10 EDO17051.1 - 0.16 11.5 0.7 1.1 8.8 0.0 2.4 1 1 1 2 2 2 0 YjeF-related protein N-terminus 3HCDH_N PF02737.13 EDO17051.1 - 0.16 11.6 0.3 0.45 10.1 0.1 2.0 1 1 1 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMN_dh PF01070.13 EDO17051.1 - 0.16 10.7 0.4 0.88 8.3 0.6 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Shikimate_DH PF01488.15 EDO17051.1 - 0.26 11.3 1.6 5.6 7.0 0.0 2.8 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase DsrD PF08679.6 EDO17051.1 - 1.5 8.8 6.7 0.34 10.9 1.3 2.5 3 0 0 3 3 1 0 Dissimilatory sulfite reductase D (DsrD) AdoHcyase_NAD PF00670.16 EDO17051.1 - 1.8 8.3 9.3 17 5.1 0.5 3.9 4 1 1 5 5 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PRELI PF04707.9 EDO17052.1 - 8.8e-43 145.5 0.3 1e-42 145.3 0.2 1.0 1 0 0 1 1 1 1 PRELI-like family HIRAN PF08797.6 EDO17052.1 - 0.055 13.4 0.1 0.2 11.5 0.1 2.0 1 1 0 1 1 1 0 HIRAN domain NMT PF01233.14 EDO17054.1 - 7.9e-81 269.4 0.2 1.7e-80 268.3 0.2 1.6 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EDO17054.1 - 3.3e-77 258.1 1.2 5.9e-77 257.3 0.8 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EDO17054.1 - 0.00023 21.0 0.0 0.0021 17.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDO17054.1 - 0.043 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.27 EDO17055.1 - 4.1e-11 42.3 6.8 1.8e-06 27.5 0.5 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat Nup160 PF11715.3 EDO17055.1 - 0.0054 14.9 0.3 0.034 12.2 0.1 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EDO17055.1 - 0.096 12.9 0.4 0.77 10.1 0.0 2.7 3 1 0 3 3 3 0 PQQ-like domain Frankia_peptide PF14407.1 EDO17055.1 - 1.1 9.0 6.7 0.17 11.6 0.6 2.5 3 0 0 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Nop PF01798.13 EDO17057.1 - 2.4e-60 202.1 0.1 4.4e-60 201.3 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EDO17057.1 - 7.9e-27 92.8 0.1 1.8e-26 91.6 0.1 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EDO17057.1 - 3.8e-23 81.4 0.4 3.8e-23 81.4 0.3 2.7 2 1 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EDO17057.1 - 0.0092 15.6 45.2 0.015 14.9 31.3 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 EDO17057.1 - 0.33 10.1 22.6 0.76 8.9 15.7 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) GAGA_bind PF06217.7 EDO17057.1 - 0.4 10.6 17.7 0.61 10.0 12.3 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 EDO17057.1 - 0.51 10.1 26.2 0.8 9.5 18.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 EDO17057.1 - 1.9 8.2 13.0 3 7.5 9.0 1.4 1 0 0 1 1 1 0 DDHD domain Zip PF02535.17 EDO17057.1 - 8.4 5.2 6.7 11 4.8 4.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter POC1 PF10450.4 EDO17058.1 - 4.6e-156 517.5 2.0 5.1e-156 517.3 1.4 1.0 1 0 0 1 1 1 1 POC1 chaperone Prefoldin_2 PF01920.15 EDO17059.1 - 1e-26 92.7 9.5 1.2e-26 92.5 6.6 1.0 1 0 0 1 1 1 1 Prefoldin subunit Med4 PF10018.4 EDO17059.1 - 0.015 14.6 0.5 0.015 14.6 0.3 1.9 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF1104 PF06518.6 EDO17059.1 - 0.017 15.2 0.9 0.029 14.4 0.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) DUF4201 PF13870.1 EDO17059.1 - 0.018 14.4 1.8 0.018 14.4 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Med9 PF07544.8 EDO17059.1 - 0.025 14.3 1.7 0.025 14.3 1.2 1.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 HrpB7 PF09486.5 EDO17059.1 - 0.098 12.5 0.9 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Spc24 PF08286.6 EDO17059.1 - 0.12 12.0 7.8 2.2 8.0 0.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ADIP PF11559.3 EDO17059.1 - 0.21 11.4 4.3 0.76 9.6 0.1 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 EDO17059.1 - 0.27 9.6 5.0 0.34 9.2 3.5 1.2 1 0 0 1 1 1 0 AAA domain Sugarporin_N PF11471.3 EDO17059.1 - 0.28 10.8 9.0 0.27 10.9 1.8 2.5 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF1192 PF06698.6 EDO17059.1 - 0.32 10.8 2.2 0.23 11.2 0.3 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF1192) Seryl_tRNA_N PF02403.17 EDO17059.1 - 0.5 10.4 6.7 4.7 7.2 0.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.12 EDO17059.1 - 0.52 9.9 8.9 0.15 11.7 1.1 2.1 1 1 0 2 2 2 0 Prefoldin subunit ERM PF00769.14 EDO17059.1 - 0.6 9.6 8.1 0.86 9.0 5.6 1.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Sec2p PF06428.6 EDO17059.1 - 0.74 9.6 6.2 1.1 9.1 0.4 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Sipho_Gp157 PF05565.6 EDO17059.1 - 0.86 9.1 7.3 3.4 7.2 5.1 1.9 1 1 0 1 1 1 0 Siphovirus Gp157 Bacillus_HBL PF05791.6 EDO17059.1 - 0.94 8.8 6.0 0.35 10.2 0.6 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DMPK_coil PF08826.5 EDO17059.1 - 1.3 8.9 9.8 0.19 11.6 1.4 2.4 2 1 0 2 2 2 0 DMPK coiled coil domain like YscO PF07321.7 EDO17059.1 - 1.4 8.7 7.8 1.4 8.7 0.9 2.0 2 0 0 2 2 2 0 Type III secretion protein YscO CENP-F_leu_zip PF10473.4 EDO17059.1 - 1.7 8.4 10.4 2.5 7.9 1.1 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 EDO17059.1 - 1.9 7.3 6.5 3.1 6.6 4.5 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3847 PF12958.2 EDO17059.1 - 1.9 8.2 8.9 2 8.2 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Occludin_ELL PF07303.8 EDO17059.1 - 1.9 9.2 7.5 2.9 8.6 0.6 2.1 1 1 0 2 2 2 0 Occludin homology domain End3 PF12761.2 EDO17059.1 - 2.1 7.9 6.9 2.5 7.6 4.8 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 IncA PF04156.9 EDO17059.1 - 2.2 7.8 9.6 3.7 7.1 6.6 1.4 1 1 0 1 1 1 0 IncA protein FTA4 PF13093.1 EDO17059.1 - 3.9 6.8 6.7 8.1 5.8 4.6 1.5 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 FliJ PF02050.11 EDO17059.1 - 4.2 7.4 8.2 68 3.5 5.7 2.0 1 1 0 1 1 1 0 Flagellar FliJ protein DUF1664 PF07889.7 EDO17059.1 - 4.4 7.1 5.7 9.2 6.0 0.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 EDO17059.1 - 4.7 6.9 9.5 54 3.5 6.6 2.0 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Snf7 PF03357.16 EDO17059.1 - 4.7 6.5 8.8 0.54 9.6 1.7 2.0 2 0 0 2 2 2 0 Snf7 DUF1319 PF07028.6 EDO17059.1 - 5.3 7.2 8.5 1.2e+02 2.8 5.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) DUF641 PF04859.7 EDO17059.1 - 5.4 6.7 6.3 2.3 7.9 1.1 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Tropomyosin_1 PF12718.2 EDO17059.1 - 5.8 6.7 11.8 52 3.6 8.2 2.0 1 1 0 1 1 1 0 Tropomyosin like DivIC PF04977.10 EDO17059.1 - 6.4 6.3 10.3 4.2 6.9 0.5 2.2 2 0 0 2 2 2 0 Septum formation initiator Cortex-I_coil PF09304.5 EDO17059.1 - 7.3 6.6 10.5 94 3.1 7.3 2.0 1 1 0 1 1 1 0 Cortexillin I, coiled coil COQ9 PF08511.6 EDO17060.1 - 1.8e-21 75.4 0.2 3.6e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 COQ9 ADH_N PF08240.7 EDO17061.1 - 1.1e-25 89.4 2.9 1.1e-25 89.4 2.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO17061.1 - 1e-19 70.3 0.2 1.9e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EDO17061.1 - 4.7e-05 22.6 0.1 8.2e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EDO17061.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EDO17061.1 - 0.014 14.8 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ELFV_dehydrog PF00208.16 EDO17061.1 - 0.041 13.4 2.0 0.069 12.7 1.4 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.1 EDO17061.1 - 0.075 13.2 0.1 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 EDO17061.1 - 0.088 12.8 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HycI PF01750.13 EDO17061.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase maturation protease zf-RanBP PF00641.13 EDO17062.1 - 2.6e-20 71.2 10.4 1.8e-11 42.9 0.9 2.8 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EDO17062.1 - 3.7e-09 36.1 0.0 0.00014 21.4 0.0 2.8 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO17062.1 - 0.00025 20.9 0.0 0.0035 17.3 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Angiomotin_C PF12240.3 EDO17062.1 - 0.15 11.5 5.0 0.36 10.2 3.5 1.6 1 0 0 1 1 1 0 Angiomotin C terminal DZR PF12773.2 EDO17062.1 - 0.46 10.3 8.9 4.6 7.1 1.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon AAA_18 PF13238.1 EDO17063.1 - 1.3e-27 96.6 1.0 1.7e-27 96.2 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO17063.1 - 3.4e-14 53.6 0.9 7.7e-14 52.5 0.2 1.7 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EDO17063.1 - 0.0002 21.4 0.1 0.00063 19.8 0.0 1.8 2 0 0 2 2 2 1 RNA helicase Thymidylate_kin PF02223.12 EDO17063.1 - 0.00051 19.4 0.0 0.38 10.1 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_28 PF13521.1 EDO17063.1 - 0.00057 19.8 0.0 0.0023 17.9 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDO17063.1 - 0.00066 19.8 0.0 0.0028 17.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDO17063.1 - 0.001 18.9 0.0 0.0023 17.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDO17063.1 - 0.0011 18.9 0.2 0.0015 18.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EDO17063.1 - 0.0015 18.3 0.0 0.31 10.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 EDO17063.1 - 0.0021 16.8 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein ADK PF00406.17 EDO17063.1 - 0.0023 17.7 0.0 0.39 10.5 0.0 2.3 2 1 0 2 2 2 1 Adenylate kinase AAA PF00004.24 EDO17063.1 - 0.007 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.5 EDO17063.1 - 0.0073 15.5 0.0 0.023 13.8 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 ABC_tran PF00005.22 EDO17063.1 - 0.01 16.1 0.4 0.072 13.3 0.3 2.0 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 EDO17063.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EDO17063.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EDO17063.1 - 0.021 14.5 0.0 0.06 13.0 0.0 1.7 2 1 0 2 2 2 0 NTPase AAA_10 PF12846.2 EDO17063.1 - 0.023 14.1 0.0 0.054 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain Viral_helicase1 PF01443.13 EDO17063.1 - 0.024 14.1 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 EDO17063.1 - 0.038 13.0 0.0 0.075 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin2 PF13189.1 EDO17063.1 - 0.041 13.7 0.3 0.2 11.5 0.1 2.1 1 1 0 1 1 1 0 Cytidylate kinase-like family FtsK_SpoIIIE PF01580.13 EDO17063.1 - 0.065 12.7 0.3 0.13 11.6 0.1 1.6 1 1 1 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EDO17063.1 - 0.067 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 EDO17063.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NOT2_3_5 PF04153.13 EDO17064.1 - 8.6e-35 119.5 1.3 1.1e-34 119.2 0.9 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Imm43 PF15602.1 EDO17064.1 - 0.068 13.1 0.1 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 43 zf-Mss51 PF13824.1 EDO17065.1 - 2.5e-16 59.2 1.5 4.2e-16 58.5 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 EDO17065.1 - 0.03 13.8 0.1 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Heme_oxygenase PF01126.15 EDO17066.1 - 7.3e-14 51.8 0.8 6.5e-13 48.7 0.5 2.1 1 1 0 1 1 1 1 Heme oxygenase CENP-X PF09415.5 EDO17067.1 - 8.8e-28 95.9 1.0 9.8e-28 95.7 0.7 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 EDO17067.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sel1 PF08238.7 EDO17068.1 - 1.6e-17 63.4 17.8 0.00097 19.6 0.7 7.6 8 0 0 8 8 8 4 Sel1 repeat TPR_1 PF00515.23 EDO17068.1 - 2.9e-08 32.9 4.0 0.025 14.1 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDO17068.1 - 1.5e-06 27.7 6.9 6.2e-06 25.7 0.3 4.4 3 1 0 3 3 3 1 TPR repeat TPR_8 PF13181.1 EDO17068.1 - 5.5e-05 22.6 2.8 3.4 7.6 0.0 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO17068.1 - 6.1e-05 22.6 6.9 0.25 11.3 0.0 5.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO17068.1 - 0.001 18.9 6.9 0.43 10.5 0.3 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDO17068.1 - 0.0028 17.3 4.7 0.97 9.3 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO17068.1 - 0.0049 17.5 0.2 0.0049 17.5 0.2 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO17068.1 - 0.0057 17.0 11.4 1.3 9.6 0.0 5.9 5 1 0 5 5 5 1 Tetratricopeptide repeat Guanylate_cyc PF00211.15 EDO17068.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain WD40 PF00400.27 EDO17069.1 - 5.6e-43 143.3 19.3 5.5e-10 38.7 0.5 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EDO17069.1 - 0.0018 18.0 9.2 0.048 13.3 1.0 3.5 2 1 2 5 5 5 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 EDO17069.1 - 0.011 15.4 0.1 2.9 7.7 0.0 3.6 4 0 0 4 4 4 0 YmzC-like protein Kelch_6 PF13964.1 EDO17069.1 - 0.18 12.0 0.9 8 6.8 0.0 3.1 3 0 0 3 3 3 0 Kelch motif PNP_UDP_1 PF01048.15 EDO17070.1 - 6.2e-45 152.9 0.0 7.4e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Pkinase PF00069.20 EDO17071.1 - 2.9e-67 226.5 0.0 5.5e-67 225.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17071.1 - 4.5e-40 137.3 0.0 8.3e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17071.1 - 5e-05 22.3 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF4219 PF13961.1 EDO17071.1 - 0.15 11.5 0.4 0.36 10.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) APH PF01636.18 EDO17071.1 - 0.23 11.1 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 EDO17073.1 - 2.1e-12 46.4 8.2 0.00079 19.2 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat CBS PF00571.23 EDO17074.1 - 1.1e-22 79.5 0.4 6.7e-06 25.7 0.0 5.3 5 0 0 5 5 5 5 CBS domain Sirohm_synth_C PF14823.1 EDO17075.1 - 6e-26 89.5 0.4 1.9e-25 87.9 0.2 1.9 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal NAD_binding_7 PF13241.1 EDO17075.1 - 1e-24 86.7 0.0 2.2e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 EDO17075.1 - 1.2e-14 52.9 1.1 2.3e-14 52.0 0.8 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 EDO17075.1 - 0.0031 17.6 0.1 0.043 13.9 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DUF1425 PF07233.7 EDO17075.1 - 0.0059 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1425) Herpes_ori_bp PF02399.10 EDO17075.1 - 0.012 13.6 0.2 0.016 13.1 0.1 1.1 1 0 0 1 1 1 0 Origin of replication binding protein Pyr_redox_3 PF13738.1 EDO17075.1 - 0.16 11.9 0.0 0.39 10.7 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4441 PF14536.1 EDO17075.1 - 0.72 9.8 6.6 1.1 9.2 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4441) RRM_1 PF00076.17 EDO17076.1 - 3.1e-44 148.4 0.0 3e-17 62.0 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO17076.1 - 1.3e-30 105.1 0.0 4.9e-12 45.6 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO17076.1 - 2.3e-23 81.7 0.0 4.1e-11 42.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO17076.1 - 1.2e-06 28.1 0.0 4.8e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EDO17076.1 - 0.0016 18.2 0.0 0.028 14.2 0.0 2.8 3 0 0 3 3 3 1 RNA binding motif Cornichon PF03311.9 EDO17077.1 - 2.3e-51 173.2 10.0 2.6e-51 173.0 7.0 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1673 PF07895.6 EDO17077.1 - 0.055 12.9 2.2 0.079 12.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Cellulase PF00150.13 EDO17079.1 - 1.7e-12 47.1 0.6 5.6e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF1708 PF08101.6 EDO17080.1 - 9.2e-161 535.3 12.6 9.2e-161 535.3 8.7 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1708) Transaldolase PF00923.14 EDO17081.1 - 7e-98 327.2 0.1 8.2e-98 327.0 0.1 1.0 1 0 0 1 1 1 1 Transaldolase SNF2_N PF00176.18 EDO17083.1 - 1.8e-75 253.5 0.2 5.1e-75 252.0 0.1 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EDO17083.1 - 1.5e-30 105.4 0.8 1.5e-30 105.4 0.6 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EDO17083.1 - 6.6e-23 80.1 1.3 1.8e-13 49.9 0.1 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EDO17083.1 - 6.7e-16 57.9 0.0 6.3e-15 54.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 EDO17083.1 - 0.03 14.3 0.4 0.16 12.0 0.0 2.5 3 0 0 3 3 3 0 Myb-like DNA-binding domain ChaC PF04752.7 EDO17084.1 - 4.3e-54 183.1 0.0 5.4e-54 182.8 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Rad4 PF03835.10 EDO17085.1 - 1.8e-30 105.2 3.1 1.8e-30 105.2 2.2 2.7 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EDO17085.1 - 1.4e-24 85.6 0.8 2.6e-24 84.7 0.5 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EDO17085.1 - 3.3e-20 71.3 0.0 8e-20 70.1 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EDO17085.1 - 2.3e-09 37.4 0.3 2.3e-09 37.4 0.2 3.6 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EDO17085.1 - 9.5e-05 22.5 0.1 0.00035 20.7 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily SPT2 PF08243.6 EDO17086.1 - 1.2e-27 96.5 28.9 4.7e-27 94.6 20.1 2.1 1 0 0 1 1 1 1 SPT2 chromatin protein SPX PF03105.14 EDO17087.1 - 4.8e-13 49.5 35.0 1.5e-09 38.0 5.8 5.0 3 1 1 4 4 4 2 SPX domain PGAP1 PF07819.8 EDO17087.1 - 0.0088 15.6 0.4 0.03 13.9 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein HAD_2 PF13419.1 EDO17088.1 - 2.1e-17 63.9 0.0 3e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDO17088.1 - 3e-06 26.8 0.0 7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDO17088.1 - 0.09 13.1 0.0 0.31 11.4 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Xol-1_N PF09108.5 EDO17088.1 - 0.16 11.6 2.3 1.3 8.7 0.1 2.7 2 1 1 3 3 3 0 Switch protein XOL-1, N-terminal HATPase_c_3 PF13589.1 EDO17089.1 - 1.1e-12 47.8 1.1 4.1e-12 45.9 0.8 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EDO17089.1 - 2.2e-12 46.4 0.3 5.9e-12 45.0 0.1 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EDO17089.1 - 5.5e-11 42.1 0.3 1.4e-10 40.8 0.2 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3827 PF12877.2 EDO17091.1 - 0.18 9.8 2.1 0.1 10.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) MIF4G_like PF09088.6 EDO17092.1 - 9.4e-59 198.0 1.7 2.6e-58 196.6 1.2 1.8 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EDO17092.1 - 6.7e-51 172.9 4.4 6.7e-51 172.9 3.0 2.2 2 0 0 2 2 2 1 MIF4G like DUF4029 PF13221.1 EDO17092.1 - 0.045 14.1 5.2 0.36 11.2 0.5 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4029) HDOD PF08668.7 EDO17092.1 - 0.046 12.9 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 HDOD domain zf-C3HC4_3 PF13920.1 EDO17094.1 - 2.7e-08 33.3 11.2 4.8e-08 32.5 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO17094.1 - 3.2 7.8 15.4 7.4 6.6 10.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tom22 PF04281.8 EDO17094.1 - 3.7 7.0 10.8 0.83 9.1 4.2 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 AICARFT_IMPCHas PF01808.13 EDO17095.1 - 9.6e-119 396.1 0.0 1.3e-118 395.6 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EDO17095.1 - 3.1e-24 84.7 0.6 5.8e-24 83.8 0.0 1.8 2 0 0 2 2 2 1 MGS-like domain Ribosomal_L15e PF00827.12 EDO17096.1 - 6.9e-90 299.7 14.8 7.9e-90 299.5 10.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 Aminotran_1_2 PF00155.16 EDO17098.1 - 2.4e-76 257.0 0.0 2.8e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_L5_C PF00673.16 EDO17099.1 - 3.6e-23 81.1 0.0 5.4e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EDO17099.1 - 3.3e-20 71.6 0.1 8.6e-20 70.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 BCAS2 PF05700.6 EDO17100.1 - 4.4e-06 26.3 10.1 9.3e-06 25.2 7.0 1.6 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4149 PF13664.1 EDO17102.1 - 2.5e-19 69.1 1.3 2.5e-19 69.1 0.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MAS20 PF02064.10 EDO17103.1 - 3.3e-17 62.5 0.1 1.3e-16 60.5 0.0 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor PsbN PF02468.10 EDO17103.1 - 0.15 11.6 0.6 0.29 10.7 0.4 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) SLX9 PF15341.1 EDO17104.1 - 1.1e-22 80.7 14.0 1.1e-22 80.7 9.7 1.6 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 DUF3818 PF12825.2 EDO17105.1 - 2.3e-118 394.7 9.8 2.3e-118 394.7 6.8 2.0 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EDO17105.1 - 4.6e-45 152.6 6.9 1.5e-44 150.9 4.8 2.0 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EDO17105.1 - 1.5e-10 40.8 1.4 9.6e-10 38.2 0.2 2.9 2 0 0 2 2 2 1 PX domain DUF2403 PF10290.4 EDO17106.1 - 0.076 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Glycine-rich protein domain (DUF2403) PALP PF00291.20 EDO17107.1 - 1.1e-56 192.3 0.0 1.3e-56 192.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.16 EDO17107.1 - 0.078 12.5 0.0 0.28 10.7 0.0 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_C25_C PF03785.9 EDO17107.1 - 0.12 12.1 0.5 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain CTP_transf_2 PF01467.21 EDO17108.1 - 7e-37 126.9 0.0 1.1e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase HOOK PF05622.7 EDO17108.1 - 0.0033 15.3 0.0 0.0045 14.8 0.0 1.0 1 0 0 1 1 1 1 HOOK protein DUF4112 PF13430.1 EDO17109.1 - 2.1e-31 107.9 0.3 3e-31 107.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) SOBP PF15279.1 EDO17109.1 - 0.44 10.8 26.5 0.6 10.4 18.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Neur_chan_memb PF02932.11 EDO17109.1 - 5.2 6.8 19.7 5.6 6.7 11.7 2.1 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pex24p PF06398.6 EDO17110.1 - 3.1e-92 309.1 9.6 5e-92 308.4 6.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin zf-CCCH PF00642.19 EDO17111.1 - 1.8e-09 37.0 3.0 1.8e-09 37.0 2.0 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EDO17111.1 - 2.9e-09 36.8 10.8 5.5e-09 35.9 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO17111.1 - 3.2e-09 36.2 6.5 5.6e-09 35.5 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO17111.1 - 7.5e-08 32.0 6.1 1.4e-07 31.1 4.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EDO17111.1 - 2.4e-07 30.3 10.8 4.4e-07 29.5 7.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO17111.1 - 3.5e-06 26.5 10.9 7.2e-06 25.5 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO17111.1 - 0.0017 18.1 8.3 0.0017 18.1 5.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EDO17111.1 - 0.0026 17.4 4.5 0.0026 17.4 3.1 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EDO17111.1 - 0.0028 17.3 3.5 0.0058 16.3 2.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-P11 PF03854.9 EDO17111.1 - 0.25 10.8 7.9 0.65 9.5 5.4 1.6 1 1 0 1 1 1 0 P-11 zinc finger Prok-RING_4 PF14447.1 EDO17111.1 - 1 8.9 8.1 2.8 7.5 5.6 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 EDO17111.1 - 9.8 6.3 13.8 23 5.1 8.9 2.2 2 1 0 2 2 2 0 RING-H2 zinc finger Mus7 PF09462.5 EDO17112.1 - 2.3e-21 76.3 32.9 2.3e-19 69.6 6.0 2.9 2 1 1 3 3 3 2 Mus7/MMS22 family dCMP_cyt_deam_1 PF00383.17 EDO17113.1 - 1.9e-08 33.8 0.0 3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region EF1_GNE PF00736.14 EDO17114.1 - 2.8e-32 110.2 2.0 2.8e-32 110.2 1.4 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EDO17114.1 - 1.1e-12 47.7 2.2 1.1e-12 47.7 1.6 3.1 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EDO17114.1 - 0.012 16.0 0.0 0.035 14.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EDO17114.1 - 0.048 13.5 0.1 0.73 9.7 0.0 2.4 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EDO17114.1 - 0.081 12.9 0.2 1.2 9.1 0.1 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DNA_pol3_a_NII PF11490.3 EDO17114.1 - 0.22 11.1 0.2 0.22 11.1 0.2 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II B-block_TFIIIC PF04182.7 EDO17115.1 - 1.2e-18 66.6 1.3 4.6e-18 64.8 0.1 2.7 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC PCI PF01399.22 EDO17115.1 - 0.012 15.8 3.5 0.39 11.0 0.3 3.4 2 1 1 3 3 3 0 PCI domain 3Beta_HSD PF01073.14 EDO17116.1 - 1.7e-84 282.8 0.0 2.1e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EDO17116.1 - 7.5e-28 97.5 0.0 9.1e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EDO17116.1 - 1.2e-14 53.8 0.0 7.9e-14 51.1 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EDO17116.1 - 6.1e-13 48.3 0.0 8.8e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EDO17116.1 - 3e-10 40.4 0.0 4.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EDO17116.1 - 4.4e-08 32.3 0.0 8.1e-08 31.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EDO17116.1 - 7e-05 22.1 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EDO17116.1 - 0.00067 19.6 0.0 0.0018 18.1 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO17116.1 - 0.078 12.6 0.0 0.4 10.3 0.0 2.0 1 1 0 1 1 1 0 KR domain AP_endonuc_2 PF01261.19 EDO17116.1 - 0.15 11.3 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Rep_fac-A_C PF08646.5 EDO17117.1 - 5.6e-56 188.3 4.0 5.4e-53 178.6 0.5 3.0 3 0 0 3 3 3 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 EDO17117.1 - 1.9e-18 66.0 0.2 2e-08 33.9 0.0 4.4 4 0 0 4 4 4 4 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 EDO17117.1 - 1.2e-05 24.9 0.0 4.3e-05 23.2 0.0 2.0 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.9 EDO17117.1 - 0.052 13.6 0.3 0.5 10.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF223 TPP1 PF10341.4 EDO17117.1 - 0.068 13.1 0.2 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD E1-E2_ATPase PF00122.15 EDO17118.1 - 2.1e-62 210.1 7.9 3.9e-62 209.2 5.5 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDO17118.1 - 9e-24 85.0 0.0 1.9e-23 84.0 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDO17118.1 - 1.9e-14 54.2 0.0 5.2e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDO17118.1 - 1.3e-11 43.7 0.0 3.8e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDO17118.1 - 0.0012 18.4 0.1 0.0027 17.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO17118.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF3134 PF11332.3 EDO17118.1 - 5.9 7.0 7.8 16 5.6 5.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) SH3_1 PF00018.23 EDO17119.1 - 1.8e-39 132.8 5.9 4.8e-15 54.6 0.0 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 EDO17119.1 - 8.2e-35 118.2 0.1 1.6e-34 117.3 0.1 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EDO17119.1 - 2.4e-34 116.6 7.8 2.4e-12 46.2 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EDO17119.1 - 1.2e-29 101.5 0.3 7.1e-10 38.2 0.0 4.6 4 0 0 4 4 4 3 Variant SH3 domain SAM_1 PF00536.25 EDO17119.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Molydop_binding PF01568.16 EDO17119.1 - 0.061 13.1 0.1 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain DUF3104 PF11302.3 EDO17119.1 - 0.084 12.2 0.1 0.31 10.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Aconitase PF00330.15 EDO17120.1 - 6.2e-192 638.2 0.2 7.4e-192 637.9 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDO17120.1 - 9.5e-47 158.3 0.0 1.9e-46 157.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain HSCB_C PF07743.8 EDO17121.1 - 2.5e-17 63.1 6.7 3.3e-17 62.6 2.3 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EDO17121.1 - 7.7e-12 44.7 0.3 1.7e-11 43.6 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1664 PF07889.7 EDO17121.1 - 1.4 8.7 4.2 2.4 7.9 2.5 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Pam16 PF03656.8 EDO17121.1 - 1.4 8.6 4.2 1.8 8.3 0.5 2.2 2 0 0 2 2 2 0 Pam16 CK_II_beta PF01214.13 EDO17122.1 - 1.4e-73 246.3 0.6 2.5e-73 245.5 0.4 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit DUF1894 PF08979.6 EDO17122.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1894) CHD5 PF04420.9 EDO17123.1 - 3.6e-52 176.2 1.2 3.6e-52 176.2 0.8 1.5 2 0 0 2 2 2 1 CHD5-like protein NIT PF08376.5 EDO17123.1 - 0.064 12.7 0.3 0.098 12.1 0.2 1.2 1 0 0 1 1 1 0 Nitrate and nitrite sensing Erp_C PF06780.6 EDO17123.1 - 0.18 11.6 6.8 0.025 14.4 2.1 1.5 2 0 0 2 2 2 0 Erp protein C-terminus Allexi_40kDa PF05549.6 EDO17123.1 - 0.37 10.0 3.3 0.16 11.2 0.8 1.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein CENP-H PF05837.7 EDO17123.1 - 0.47 10.6 9.8 0.55 10.4 3.7 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) IncA PF04156.9 EDO17123.1 - 0.6 9.6 4.9 0.1 12.1 0.9 1.6 2 0 0 2 2 2 0 IncA protein Seryl_tRNA_N PF02403.17 EDO17123.1 - 4 7.5 9.0 1.7 8.6 2.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UPF0564 PF10595.4 EDO17124.1 - 0.037 12.9 0.2 0.037 12.9 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 STT3 PF02516.9 EDO17125.1 - 5.2e-135 451.1 51.4 4.2e-134 448.1 35.6 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit FYVE PF01363.16 EDO17126.1 - 7e-16 57.8 5.7 1.5e-15 56.8 4.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EDO17126.1 - 1.8 8.4 11.6 6 6.8 8.0 1.9 1 1 0 1 1 1 0 AN1-like Zinc finger Acyltransferase PF01553.16 EDO17127.1 - 1.1e-10 41.0 0.0 1.1e-09 37.8 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase PCI_Csn8 PF10075.4 EDO17128.1 - 0.032 13.9 0.6 0.05 13.3 0.4 1.4 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 PCI PF01399.22 EDO17128.1 - 0.079 13.2 0.8 0.3 11.4 0.2 2.2 1 1 1 2 2 2 0 PCI domain Med3 PF11593.3 EDO17129.1 - 1.7e-145 485.0 117.7 9.2e-103 344.4 20.1 3.0 1 1 1 2 2 2 2 Mediator complex subunit 3 fungal Spc7 PF08317.6 EDO17129.1 - 0.02 13.5 1.9 0.033 12.8 1.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Collagen PF01391.13 EDO17129.1 - 0.085 12.4 2.7 0.22 11.0 1.9 1.7 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Trp_syntA PF00290.15 EDO17130.1 - 7.3e-95 316.3 0.1 1.1e-94 315.8 0.1 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EDO17130.1 - 1.6e-45 155.6 1.1 3.7e-45 154.4 0.4 1.9 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 EDO17130.1 - 0.091 11.9 0.1 0.32 10.1 0.1 1.8 2 0 0 2 2 2 0 PcrB family BtpA PF03437.10 EDO17130.1 - 0.092 11.9 0.8 0.72 9.0 0.1 2.3 2 0 0 2 2 2 0 BtpA family Pkinase PF00069.20 EDO17131.1 - 1.6e-55 188.1 0.1 5.4e-54 183.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17131.1 - 3.3e-20 72.2 0.0 6.6e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17131.1 - 0.014 14.4 0.0 0.059 12.3 0.0 1.9 1 1 1 2 2 2 0 Kinase-like DUF3353 PF11833.3 EDO17131.1 - 0.34 10.3 0.6 0.67 9.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) TFR_dimer PF04253.10 EDO17132.1 - 5.6e-39 132.5 0.0 1.2e-38 131.5 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EDO17132.1 - 0.00072 19.2 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 PA domain Sec63 PF02889.11 EDO17134.1 - 1.2e-24 87.1 0.1 3.3e-21 75.8 0.0 2.4 1 1 1 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 EDO17134.1 - 1.2e-19 69.8 1.0 3.6e-19 68.2 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain Val_tRNA-synt_C PF10458.4 EDO17134.1 - 0.025 14.6 0.2 0.025 14.6 0.1 1.9 2 0 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Sporozoite_P67 PF05642.6 EDO17134.1 - 0.031 12.1 3.2 0.057 11.2 2.2 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 EDO17134.1 - 2.5 5.9 22.7 5 4.9 15.8 1.5 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EDO17134.1 - 9.7 4.7 28.4 16 4.1 19.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Acetyltransf_1 PF00583.19 EDO17135.1 - 9.7e-16 57.5 0.0 1.3e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO17135.1 - 5.5e-08 32.8 0.1 7.8e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO17135.1 - 8.7e-06 25.8 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EDO17135.1 - 9e-06 25.7 0.4 1.1e-05 25.4 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDO17135.1 - 9e-06 25.3 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EDO17135.1 - 0.00054 19.8 0.0 0.00075 19.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2962 PF11176.3 EDO17137.1 - 1e-52 177.8 10.1 1.2e-52 177.5 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) MRC1 PF09444.5 EDO17137.1 - 0.07 13.4 6.0 0.13 12.6 4.2 1.4 1 0 0 1 1 1 0 MRC1-like domain HATPase_c PF02518.21 EDO17139.1 - 0.096 12.4 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase adh_short PF00106.20 EDO17140.1 - 2.4e-13 50.3 0.0 4.9e-12 46.0 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO17140.1 - 1.7e-07 31.3 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase G6PD_N PF00479.17 EDO17140.1 - 0.00021 21.5 0.5 0.00033 20.9 0.3 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain KR PF08659.5 EDO17140.1 - 0.00036 20.2 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EDO17140.1 - 0.00041 19.8 0.0 0.00072 19.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EDO17140.1 - 0.00096 19.2 0.0 0.19 11.6 0.0 2.8 1 1 0 2 2 2 1 NADH(P)-binding 3HCDH_N PF02737.13 EDO17140.1 - 0.0097 15.5 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 EDO17140.1 - 0.014 14.5 1.4 0.29 10.2 1.0 2.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2730 PF10805.3 EDO17140.1 - 0.035 13.8 0.0 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) SSV1_ORF_D-335 PF07935.6 EDO17140.1 - 0.23 11.2 1.4 0.46 10.2 1.0 1.5 1 0 0 1 1 1 0 ORF D-335-like protein tRNA-synt_1 PF00133.17 EDO17141.1 - 1.1e-41 142.5 0.0 9.1e-33 113.1 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EDO17141.1 - 4.3e-20 71.7 2.1 4.4e-11 42.0 0.0 4.1 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EDO17141.1 - 5.5e-12 45.6 0.1 5.5e-12 45.6 0.1 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EDO17141.1 - 1e-06 28.1 1.8 1.1e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Pet20 PF08692.5 EDO17142.1 - 2.3e-22 79.4 0.2 1.4e-10 41.2 0.0 2.5 1 1 1 2 2 2 2 Mitochondrial protein Pet20 AAA_assoc PF14363.1 EDO17143.1 - 0.057 13.4 0.6 0.42 10.6 0.4 2.4 1 1 0 1 1 1 0 Domain associated at C-terminal with AAA UPF0449 PF15136.1 EDO17143.1 - 0.088 13.0 2.9 31 4.8 0.1 4.0 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 Glutaredoxin PF00462.19 EDO17144.1 - 0.0051 16.7 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin Asp PF00026.18 EDO17145.1 - 6.3e-105 350.9 0.0 7.8e-105 350.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO17145.1 - 3.4e-11 43.3 0.0 6.6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EDO17145.1 - 4.2e-05 23.1 0.0 0.00059 19.4 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EDO17145.1 - 0.0002 21.7 0.0 0.12 12.8 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease Pkinase PF00069.20 EDO17146.1 - 1.9e-75 253.3 0.0 3.5e-75 252.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17146.1 - 5.6e-36 123.9 0.0 1.1e-35 123.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EDO17146.1 - 7.4e-28 96.4 2.0 3.9e-15 55.7 0.0 3.1 3 0 0 3 3 3 2 FHA domain Kinase-like PF14531.1 EDO17146.1 - 1e-08 34.5 0.0 2.2e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDO17146.1 - 4.7e-05 22.5 0.0 8.6e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO17146.1 - 6.2e-05 22.8 0.0 0.017 14.8 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF1179 PF06678.6 EDO17146.1 - 3.2 8.0 6.2 0.9 9.8 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) WD40 PF00400.27 EDO17147.1 - 6.8e-49 162.0 16.2 2.7e-08 33.3 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 EDO17147.1 - 0.003 17.3 0.0 9.8 6.0 0.0 4.0 5 0 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EDO17147.1 - 0.046 11.8 1.5 6.2 4.8 0.0 2.9 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Mur_ligase_M PF08245.7 EDO17148.1 - 7.9e-05 22.7 3.3 0.0032 17.5 0.5 3.4 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EDO17148.1 - 0.0084 16.1 0.0 0.025 14.6 0.0 1.8 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain Coatomer_b_Cpla PF14806.1 EDO17148.1 - 0.045 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Pkinase PF00069.20 EDO17149.1 - 2.7e-67 226.6 0.1 4.9e-67 225.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17149.1 - 2.7e-39 134.8 0.0 4.3e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17149.1 - 3.5e-07 29.4 0.0 9.9e-07 27.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO17149.1 - 0.068 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO17149.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SGT1 PF07093.6 EDO17150.1 - 7.6e-54 183.1 30.7 1.9e-49 168.5 1.3 2.4 2 1 1 3 3 3 2 SGT1 protein ACPS PF01648.15 EDO17152.1 - 1.2e-14 54.1 0.0 4.5e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF1749 PF08538.5 EDO17153.1 - 2.8e-95 318.7 0.2 3.4e-95 318.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EDO17153.1 - 2.7e-10 40.5 0.0 3.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO17153.1 - 4.2e-09 36.3 0.0 1.1e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO17153.1 - 1.5e-06 27.9 0.0 1.3e-05 24.8 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EDO17153.1 - 0.00053 19.4 0.2 0.0056 16.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Peptidase_S9 PF00326.16 EDO17153.1 - 0.0068 15.6 0.0 0.048 12.8 0.0 2.3 2 1 1 3 3 3 1 Prolyl oligopeptidase family DUF915 PF06028.6 EDO17153.1 - 0.03 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase PF07224.6 EDO17153.1 - 0.044 12.5 0.0 0.08 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase LCAT PF02450.10 EDO17153.1 - 0.044 12.7 0.0 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Oxysterol_BP PF01237.13 EDO17155.1 - 9.6e-88 294.0 1.2 1.2e-87 293.7 0.8 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DHFR_1 PF00186.14 EDO17156.1 - 4.8e-29 101.0 0.0 7.4e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase chaperone_DMP PF10448.4 EDO17157.1 - 5.8e-34 117.0 2.1 6.5e-34 116.8 1.4 1.0 1 0 0 1 1 1 1 20S proteasome chaperone DUF320 PF03777.8 EDO17157.1 - 0.039 13.7 0.8 0.058 13.1 0.4 1.4 1 1 0 1 1 1 0 Small secreted domain (DUF320) Ribosomal_L35Ae PF01247.13 EDO17158.1 - 2.4e-42 142.6 1.2 2.7e-42 142.4 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EDO17158.1 - 0.0017 18.2 0.0 1.1 9.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Pkinase PF00069.20 EDO17159.1 - 7.2e-67 225.2 0.0 1.6e-66 224.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17159.1 - 9e-40 136.3 0.0 1.7e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17159.1 - 5.2e-07 28.9 0.0 9.7e-07 28.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO17159.1 - 0.0016 17.5 0.1 0.013 14.5 0.1 2.3 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO17159.1 - 0.012 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family GrpE PF01025.14 EDO17160.1 - 5.7e-50 169.1 7.5 7.3e-50 168.7 5.2 1.1 1 0 0 1 1 1 1 GrpE Uds1 PF15456.1 EDO17160.1 - 0.003 17.5 2.4 0.0053 16.7 1.7 1.3 1 0 0 1 1 1 1 Up-regulated During Septation Toxin_trans PF07952.7 EDO17160.1 - 0.028 13.3 1.7 0.035 13.0 1.2 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Atg14 PF10186.4 EDO17160.1 - 0.033 13.1 4.0 0.045 12.6 2.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ALMT PF11744.3 EDO17160.1 - 0.059 12.0 1.7 0.079 11.5 1.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter IncA PF04156.9 EDO17160.1 - 0.19 11.3 4.1 0.25 10.8 2.8 1.2 1 0 0 1 1 1 0 IncA protein Syntaxin_2 PF14523.1 EDO17160.1 - 0.22 11.5 6.7 0.51 10.3 4.6 1.6 1 1 0 1 1 1 0 Syntaxin-like protein Pox_A_type_inc PF04508.7 EDO17160.1 - 0.26 11.1 1.8 0.73 9.7 1.2 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat OmpH PF03938.9 EDO17160.1 - 0.36 10.7 6.2 0.56 10.1 4.3 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Pkinase PF00069.20 EDO17161.1 - 3.9e-68 229.4 0.0 5.7e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17161.1 - 1e-36 126.3 0.0 2e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17161.1 - 4.6e-10 38.9 0.0 8.2e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO17161.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO17161.1 - 0.033 13.9 0.0 0.083 12.6 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDO17161.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EDO17161.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family LRR_6 PF13516.1 EDO17162.1 - 0.0015 18.3 8.0 3.9 7.8 0.0 6.6 6 0 0 6 6 6 1 Leucine Rich repeat LRR_4 PF12799.2 EDO17162.1 - 0.0031 17.0 1.3 0.0031 17.0 0.9 7.4 6 1 1 7 7 7 5 Leucine Rich repeats (2 copies) NifU_N PF01592.11 EDO17163.1 - 1.4e-44 151.0 0.4 1.6e-44 150.8 0.3 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Mito_carr PF00153.22 EDO17164.1 - 4.8e-71 234.5 1.5 1.2e-26 92.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EDO17164.1 - 0.045 13.7 0.4 0.45 10.5 0.0 2.6 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family Acyl_transf_1 PF00698.16 EDO17165.1 - 0.045 13.0 0.0 0.46 9.7 0.0 2.0 2 0 0 2 2 2 0 Acyl transferase domain DUF2247 PF10004.4 EDO17166.1 - 0.061 13.0 0.2 0.73 9.5 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) Ribosomal_L18p PF00861.17 EDO17167.1 - 5.5e-46 155.6 0.9 6.8e-46 155.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EDO17167.1 - 2.2e-31 108.2 1.0 2.2e-31 108.2 0.7 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EDO17167.1 - 0.09 12.8 0.1 0.99 9.4 0.0 2.4 2 0 0 2 2 2 0 Threonine synthase N terminus DPPIV_N PF00930.16 EDO17168.1 - 4.6e-85 285.3 4.5 7e-85 284.7 3.1 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EDO17168.1 - 1.1e-52 178.3 0.9 1.7e-52 177.7 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EDO17168.1 - 5.2e-07 29.5 0.0 9.2e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EDO17168.1 - 0.00079 18.9 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 EDO17168.1 - 0.0027 17.6 0.0 0.043 13.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EDO17168.1 - 0.0037 16.7 2.5 0.032 13.6 0.3 2.6 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.8 EDO17168.1 - 0.0058 14.9 0.0 0.013 13.8 0.0 1.5 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.11 EDO17168.1 - 0.0083 15.5 0.1 0.4 10.0 0.0 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EDO17168.1 - 0.033 13.7 0.0 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold ISN1 PF06437.6 EDO17168.1 - 0.046 12.4 0.0 0.084 11.5 0.0 1.3 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase YEATS PF03366.11 EDO17170.1 - 6.3e-24 83.5 0.1 9.9e-24 82.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family WD40 PF00400.27 EDO17171.1 - 5.2e-42 140.2 18.0 1.3e-07 31.2 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EDO17171.1 - 0.00012 20.3 6.1 0.00028 19.1 0.5 2.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nup88 PF10168.4 EDO17171.1 - 0.0068 14.3 3.7 0.0072 14.2 1.2 1.8 1 1 1 2 2 2 1 Nuclear pore component eIF2A PF08662.6 EDO17171.1 - 0.014 15.0 1.3 0.65 9.6 0.0 3.0 2 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A TRF PF08558.5 EDO17172.1 - 1.2e-65 221.2 0.5 2e-65 220.4 0.1 1.6 1 1 1 2 2 2 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EDO17172.1 - 1.8e-08 34.2 0.4 4.8e-08 32.9 0.2 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO17172.1 - 8.4e-06 25.8 0.1 3e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Linker_histone PF00538.14 EDO17173.1 - 5.2e-36 122.5 7.4 1.2e-18 66.9 0.1 2.7 3 0 0 3 3 3 2 linker histone H1 and H5 family Mucin PF01456.12 EDO17173.1 - 0.041 13.6 20.0 0.068 12.9 13.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 EDO17173.1 - 0.25 9.0 14.6 0.33 8.6 10.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAM60A PF15396.1 EDO17173.1 - 0.27 10.9 9.0 0.67 9.6 6.2 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_C39_2 PF13529.1 EDO17173.1 - 0.85 9.9 0.0 0.85 9.9 0.0 2.7 2 1 0 2 2 2 0 Peptidase_C39 like family Peptidase_S30 PF01577.11 EDO17173.1 - 3.7 6.8 13.7 2.7 7.3 8.2 1.6 2 0 0 2 2 2 0 Potyvirus P1 protease Dynamin_N PF00350.18 EDO17174.1 - 7.7e-42 142.9 0.3 7.7e-42 142.9 0.2 3.0 3 1 0 3 3 3 1 Dynamin family Dynamin_M PF01031.15 EDO17174.1 - 0.001 17.9 11.2 0.0018 17.1 0.0 3.6 3 1 1 4 4 4 2 Dynamin central region MMR_HSR1 PF01926.18 EDO17174.1 - 0.0019 18.1 0.1 0.014 15.3 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDO17174.1 - 0.0022 18.4 0.3 0.0089 16.5 0.2 2.2 1 1 0 1 1 1 1 Miro-like protein DUF575 PF04746.7 EDO17174.1 - 0.0085 16.1 0.2 0.021 14.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF575) AAA_16 PF13191.1 EDO17174.1 - 0.044 13.7 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain RNA_pol_N PF01194.12 EDO17175.1 - 4e-29 100.4 0.5 4.6e-29 100.2 0.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit YhfH PF14149.1 EDO17175.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 YhfH-like protein WD40 PF00400.27 EDO17176.1 - 6.9e-05 22.5 8.7 0.0019 18.0 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat NAPRTase PF04095.11 EDO17177.1 - 2.2e-71 240.0 0.1 3e-71 239.5 0.1 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Y_phosphatase PF00102.22 EDO17178.1 - 4.3e-62 209.5 1.8 1.1e-61 208.1 1.2 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EDO17178.1 - 0.00096 18.7 0.1 0.0063 16.1 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EDO17178.1 - 0.0061 16.8 1.1 0.025 14.8 0.0 2.6 3 1 0 3 3 3 1 Tyrosine phosphatase family Noc2 PF03715.8 EDO17179.1 - 1.1e-121 405.2 10.1 1.1e-121 405.2 7.0 2.4 2 1 0 2 2 2 1 Noc2p family DEAD PF00270.24 EDO17180.1 - 3.7e-46 156.7 0.0 5.5e-45 152.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO17180.1 - 6.4e-27 93.2 0.1 1.5e-26 92.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO17180.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EDO17180.1 - 0.065 12.3 0.1 0.25 10.3 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EDO17180.1 - 0.082 11.2 0.0 0.24 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Mit_ribos_Mrp51 PF11709.3 EDO17181.1 - 2.1e-92 309.6 2.6 2.5e-92 309.4 1.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit SpoU_methylase PF00588.14 EDO17182.1 - 1.4e-24 86.6 0.2 4.5e-23 81.6 0.0 2.7 2 1 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EDO17182.1 - 3.5e-14 52.7 0.0 7.4e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Baculo_PEP_C PF04513.7 EDO17183.1 - 0.036 13.8 29.7 1.1 9.0 1.7 5.4 2 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EDO17183.1 - 1.7 7.7 16.9 1.2 8.1 3.6 3.6 2 1 2 4 4 4 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 EDO17183.1 - 7 3.8 51.7 0.24 8.6 22.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Peptidase_C14 PF00656.17 EDO17184.1 - 9.2e-69 231.8 0.2 1.1e-68 231.5 0.1 1.0 1 0 0 1 1 1 1 Caspase domain FHA PF00498.21 EDO17185.1 - 3.9e-13 49.3 0.3 1e-12 47.9 0.2 1.8 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EDO17185.1 - 1.3e-06 28.1 7.6 2.1e-06 27.4 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO17185.1 - 0.00071 19.6 4.4 0.0014 18.7 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EDO17185.1 - 0.0029 17.2 9.4 0.0052 16.4 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO17185.1 - 0.0046 16.5 3.6 0.0081 15.8 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDO17185.1 - 0.0048 16.7 5.1 0.015 15.1 3.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EDO17185.1 - 0.011 15.4 6.9 0.019 14.7 4.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDO17185.1 - 0.013 15.5 9.6 0.026 14.5 6.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EDO17185.1 - 0.6 9.8 4.0 1.4 8.6 2.8 1.6 1 0 0 1 1 1 0 PHD-finger SH3_9 PF14604.1 EDO17186.1 - 6.8e-27 92.7 0.1 1.1e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EDO17186.1 - 4.8e-23 80.2 0.2 4.9e-13 48.2 0.1 2.7 2 0 0 2 2 2 2 SH3 domain FCH PF00611.18 EDO17186.1 - 4.5e-22 78.0 2.0 8.6e-22 77.1 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 EDO17186.1 - 1.1e-15 56.8 0.0 4.9e-10 38.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain TRAPP PF04051.11 EDO17187.1 - 4e-32 110.8 0.0 6.1e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component zf-H2C2_2 PF13465.1 EDO17188.1 - 3.1e-22 77.7 24.4 3.1e-08 33.5 0.7 4.7 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 EDO17188.1 - 4.6e-20 70.6 30.7 6.3e-06 26.2 0.7 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO17188.1 - 1.1e-14 53.5 29.2 0.00021 21.3 0.5 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-Di19 PF05605.7 EDO17188.1 - 0.0022 18.0 7.2 0.031 14.3 0.2 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EDO17188.1 - 0.0039 17.2 19.7 0.4 10.8 0.1 4.8 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO17188.1 - 0.012 15.7 22.3 0.015 15.4 0.2 5.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-CHCC PF10276.4 EDO17188.1 - 0.69 9.7 10.5 1.3 8.9 0.7 3.3 3 0 0 3 3 3 0 Zinc-finger domain HNH PF01844.18 EDO17188.1 - 1.1 9.1 11.5 11 5.9 0.3 4.4 4 0 0 4 4 4 0 HNH endonuclease zf-C2H2_6 PF13912.1 EDO17188.1 - 1.2 9.1 18.7 0.066 13.1 0.7 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EDO17188.1 - 1.5 8.5 11.1 15 5.3 0.9 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 EDO17188.1 - 2.9 7.9 13.9 14 5.6 3.9 4.0 3 1 0 3 3 3 0 Zinc ribbon domain gag_pre-integrs PF13976.1 EDO17189.1 - 0.0014 18.2 0.4 0.0026 17.3 0.3 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain WhiA_N PF10298.4 EDO17190.1 - 0.06 13.2 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain rve PF00665.21 EDO17191.1 - 2.6e-17 63.0 0.0 5.3e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 EDO17191.1 - 1.2e-14 54.2 0.1 5.3e-13 48.8 0.1 2.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 EDO17191.1 - 0.043 13.7 0.4 1.1 9.2 0.3 2.5 1 1 0 1 1 1 0 Retroviral aspartyl protease Nup54 PF13874.1 EDO17192.1 - 0.011 15.3 2.3 0.031 13.9 1.6 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.7 EDO17192.1 - 0.025 14.4 4.0 0.32 10.8 2.8 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps51 PF08700.6 EDO17192.1 - 0.056 13.2 3.3 0.23 11.3 0.4 2.7 2 0 0 2 2 2 0 Vps51/Vps67 Rootletin PF15035.1 EDO17192.1 - 0.077 12.9 4.9 0.22 11.5 3.4 1.7 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 EDO17192.1 - 0.098 11.8 3.4 0.23 10.6 2.3 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein CALCOCO1 PF07888.6 EDO17192.1 - 0.71 8.0 7.2 0.94 7.6 5.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like NPV_P10 PF05531.7 EDO17192.1 - 3.8 7.8 5.9 64 3.8 2.2 3.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Pox_A3L PF05288.6 EDO17192.1 - 7.3 6.4 7.7 17 5.2 0.2 3.1 3 0 0 3 3 3 0 Poxvirus A3L Protein DcpS_C PF11969.3 EDO17194.1 - 1.5e-33 115.4 1.0 3e-33 114.4 0.4 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EDO17194.1 - 2.1e-26 92.4 0.2 4.2e-26 91.5 0.2 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.18 EDO17194.1 - 0.0006 20.3 0.8 0.0017 18.8 0.1 2.2 3 0 0 3 3 3 1 HIT domain MBOAT PF03062.14 EDO17195.1 - 4e-45 154.3 21.1 4e-45 154.3 14.6 2.2 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ferrochelatase PF00762.14 EDO17196.1 - 1.5e-89 300.1 0.0 1.7e-89 299.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Abhydrolase_6 PF12697.2 EDO17197.1 - 9.3e-23 81.2 0.0 1.5e-22 80.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO17197.1 - 3.1e-20 72.7 0.0 4.7e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO17197.1 - 1e-06 28.5 0.0 7.5e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EDO17197.1 - 0.00062 19.4 0.0 0.0012 18.4 0.0 1.4 2 0 0 2 2 2 1 Serine hydrolase Peptidase_S9 PF00326.16 EDO17197.1 - 0.031 13.4 0.0 0.25 10.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EDO17197.1 - 0.04 13.3 0.0 0.22 10.9 0.0 2.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase BPL_LplA_LipB PF03099.14 EDO17198.1 - 6.8e-17 61.6 0.1 1.2e-16 60.8 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PMEI PF04043.10 EDO17198.1 - 0.0046 16.8 0.1 0.36 10.7 0.0 2.5 3 0 0 3 3 3 1 Plant invertase/pectin methylesterase inhibitor DUF806 PF05657.6 EDO17198.1 - 0.026 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF806) UPF0086 PF01868.11 EDO17199.1 - 4.8e-16 58.1 0.0 1.1e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Cullin PF00888.17 EDO17200.1 - 8.5e-11 41.1 15.6 1.6e-10 40.1 10.4 1.8 1 1 0 1 1 1 1 Cullin family RhoGAP PF00620.22 EDO17201.1 - 4.3e-34 117.3 0.7 1.4e-33 115.6 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EDO17201.1 - 1.4e-12 47.6 0.1 1.4e-12 47.6 0.1 3.0 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain Methyltransf_PK PF05891.7 EDO17202.1 - 3.5e-93 310.9 0.0 3.9e-93 310.7 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EDO17202.1 - 1.3e-06 28.2 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO17202.1 - 5.7e-06 26.8 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO17202.1 - 0.0007 20.0 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO17202.1 - 0.0024 18.2 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Bin3 PF06859.7 EDO17202.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) P-mevalo_kinase PF04275.9 EDO17202.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Phosphomevalonate kinase Rif1_N PF12231.3 EDO17203.1 - 2.6e-42 145.1 18.5 2.6e-42 145.1 12.8 2.3 3 0 0 3 3 3 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.20 EDO17204.1 - 3.9e-55 186.8 0.0 5e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17204.1 - 3.5e-29 101.6 0.0 4.7e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17204.1 - 2.6e-08 33.1 0.0 4.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EDO17204.1 - 0.0057 15.5 0.0 0.065 12.0 0.0 2.1 2 0 0 2 2 2 1 Seadornavirus VP7 Kdo PF06293.9 EDO17204.1 - 0.053 12.5 0.0 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family UBX PF00789.15 EDO17205.1 - 3.4e-17 62.2 0.1 1.3e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 UBX domain DUF2578 PF10843.3 EDO17205.1 - 0.011 15.4 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2578) rRNA_proc-arch PF13234.1 EDO17207.1 - 7e-94 313.9 2.6 7e-94 313.9 1.8 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EDO17207.1 - 2.5e-62 209.3 0.2 5.2e-62 208.2 0.1 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EDO17207.1 - 1.6e-22 79.7 0.0 4.8e-21 74.9 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO17207.1 - 3e-06 26.9 0.0 7.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EDO17207.1 - 0.22 11.2 0.0 0.63 9.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain zf-C2H2 PF00096.21 EDO17209.1 - 7.2e-24 82.6 52.2 1.3e-05 25.2 0.2 9.3 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO17209.1 - 3.7e-21 74.3 45.1 8.8e-08 32.0 0.5 7.7 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO17209.1 - 3.7e-14 51.9 55.3 0.00067 19.8 0.6 9.2 9 0 0 9 9 9 5 C2H2-type zinc finger zf-met PF12874.2 EDO17209.1 - 6.2e-11 42.0 21.9 0.00055 20.0 0.8 5.4 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDO17209.1 - 1.6e-08 34.4 28.6 0.00019 21.4 0.5 5.5 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EDO17209.1 - 2.2e-07 30.5 0.3 2.2e-07 30.5 0.2 6.5 6 1 1 7 7 7 3 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EDO17209.1 - 0.19 11.7 0.1 0.19 11.7 0.1 5.8 4 1 1 5 5 5 0 Zinc ribbon domain zf-C2HC_2 PF13913.1 EDO17209.1 - 0.22 11.2 14.0 6.1 6.6 0.1 4.6 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Aminotran_1_2 PF00155.16 EDO17210.1 - 9.2e-83 278.1 0.0 1.1e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EDO17210.1 - 6.1e-06 25.5 0.0 9.7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EDO17210.1 - 0.00065 18.0 0.1 0.0015 16.9 0.1 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EDO17210.1 - 0.0007 18.4 0.0 0.0022 16.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.16 EDO17210.1 - 0.075 11.8 0.1 0.16 10.7 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class-III DUF2240 PF09999.4 EDO17210.1 - 0.14 11.5 0.0 0.37 10.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) ATP-gua_Ptrans PF00217.14 EDO17211.1 - 0.072 12.3 12.0 0.049 12.9 5.5 2.5 2 1 0 2 2 2 0 ATP:guanido phosphotransferase, C-terminal catalytic domain Ribosomal_L37 PF08561.5 EDO17212.1 - 3.3e-27 93.8 1.4 4.1e-27 93.5 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Phosphodiest PF01663.17 EDO17213.1 - 1.1e-16 61.1 1.1 7.2e-13 48.5 0.1 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EDO17213.1 - 4.1e-06 26.3 0.1 7.5e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EDO17213.1 - 0.00018 20.8 0.1 0.00045 19.5 0.1 1.8 1 1 0 1 1 1 1 Sulfatase zf-C2H2_2 PF12756.2 EDO17214.1 - 1.4e-33 114.9 7.5 5.5e-31 106.6 3.9 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EDO17214.1 - 1.6e-05 24.8 2.1 0.028 14.5 0.0 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO17214.1 - 0.0069 16.5 0.7 0.0069 16.5 0.5 2.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EDO17214.1 - 0.12 12.7 0.1 0.12 12.7 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO17214.1 - 0.21 11.9 9.0 3.7 8.0 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDO17214.1 - 0.23 11.4 1.5 0.41 10.6 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.20 EDO17215.1 - 1.8e-18 67.0 0.0 2.1e-17 63.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO17215.1 - 1.9e-11 43.9 0.0 2.6e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EDO17215.1 - 0.026 13.4 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein A_deaminase PF00962.17 EDO17216.1 - 1.9e-81 273.5 0.0 2.1e-81 273.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase TPR_1 PF00515.23 EDO17216.1 - 0.017 14.6 0.1 0.037 13.6 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3889 PF13028.1 EDO17216.1 - 0.16 11.6 0.4 0.4 10.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) Aminotran_1_2 PF00155.16 EDO17217.1 - 2.1e-15 56.5 0.0 3.5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EDO17217.1 - 0.0025 17.0 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF711 PF05167.7 EDO17217.1 - 0.043 12.5 0.0 0.066 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) Asparaginase PF00710.15 EDO17218.1 - 1.4e-18 66.8 0.1 4.8e-18 65.0 0.1 1.8 1 1 0 1 1 1 1 Asparaginase ABC_tran PF00005.22 EDO17219.1 - 1.4e-17 64.3 0.0 3e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EDO17219.1 - 3.7e-07 30.3 0.1 0.012 15.5 0.0 2.5 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 EDO17219.1 - 1.4e-05 24.4 0.0 0.022 13.9 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EDO17219.1 - 0.00022 20.3 0.1 0.21 10.5 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EDO17219.1 - 0.002 17.6 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EDO17219.1 - 0.0059 17.4 1.3 0.026 15.3 0.9 2.3 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EDO17219.1 - 0.0085 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain DUF3584 PF12128.3 EDO17219.1 - 0.01 13.2 0.1 0.013 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Dynamin_N PF00350.18 EDO17219.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Dynamin family DUF258 PF03193.11 EDO17219.1 - 0.044 12.9 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDO17219.1 - 0.054 13.6 0.7 0.18 11.9 0.5 1.9 1 1 0 1 1 1 0 AAA domain MutS_V PF00488.16 EDO17219.1 - 0.058 12.7 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 MutS domain V AAA_23 PF13476.1 EDO17219.1 - 0.059 13.6 0.1 0.26 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EDO17219.1 - 0.11 12.8 0.3 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EDO17219.1 - 0.18 10.9 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin FA_hydroxylase PF04116.8 EDO17220.1 - 8e-11 42.3 20.1 8e-11 42.3 13.9 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pkinase PF00069.20 EDO17221.1 - 7.6e-33 113.7 2.8 6.3e-32 110.7 1.9 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17221.1 - 1.3e-17 63.7 0.1 1.9e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO17221.1 - 0.0037 17.0 0.1 0.012 15.3 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Glyco_hydro_47 PF01532.15 EDO17222.1 - 6.7e-74 249.1 3.6 1.1e-73 248.4 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SHMT PF00464.14 EDO17223.1 - 1.2e-204 679.1 0.0 1.4e-204 678.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EDO17223.1 - 2.5e-05 23.5 0.0 5.2e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EDO17223.1 - 0.0003 19.8 0.0 0.0013 17.7 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDO17223.1 - 0.0026 16.5 0.0 0.0036 16.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.14 EDO17223.1 - 0.08 11.3 0.1 0.19 10.1 0.0 1.7 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DUF4456 PF14644.1 EDO17223.1 - 0.11 11.7 0.1 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Aminotran_5 PF00266.14 EDO17224.1 - 2.8e-22 78.9 0.0 3.9e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EDO17224.1 - 0.0017 18.2 0.0 0.0044 16.8 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain Met_gamma_lyase PF06838.6 EDO17224.1 - 0.013 13.8 0.2 0.024 12.9 0.2 1.5 1 1 0 1 1 1 0 Methionine gamma-lyase EspA PF03433.8 EDO17224.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 EspA-like secreted protein bZIP_2 PF07716.10 EDO17225.1 - 0.00013 21.7 7.8 0.00013 21.7 5.4 1.7 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDO17225.1 - 0.012 15.5 13.3 0.071 13.0 9.2 2.1 1 1 0 1 1 1 0 bZIP transcription factor SARA PF11409.3 EDO17225.1 - 0.049 13.5 0.6 8.6 6.3 0.8 2.6 2 0 0 2 2 2 0 Smad anchor for receptor activation (SARA) RNase_T PF00929.19 EDO17226.1 - 7.8e-30 104.3 0.1 1.2e-29 103.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF573 PF04504.9 EDO17226.1 - 0.025 14.8 1.0 0.075 13.3 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF573 PAS_9 PF13426.1 EDO17227.1 - 0.028 14.8 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 PAS domain Pkinase PF00069.20 EDO17228.1 - 1e-59 201.8 0.1 3.4e-37 128.0 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17228.1 - 9.1e-27 93.7 0.5 1.2e-20 73.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EDO17228.1 - 1e-05 25.5 0.0 2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EDO17228.1 - 3e-05 23.1 0.3 0.00043 19.3 0.0 2.6 2 1 1 3 3 3 1 Kinase-like APH PF01636.18 EDO17228.1 - 0.00054 19.7 0.0 0.16 11.6 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EDO17228.1 - 0.0084 15.4 0.3 0.024 13.9 0.2 1.7 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 EDO17228.1 - 0.014 14.5 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family B3_4 PF03483.12 EDO17229.1 - 4.3e-27 94.6 0.0 8.8e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EDO17229.1 - 2.3e-19 68.9 0.0 5.2e-16 58.2 0.0 2.8 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 EDO17229.1 - 0.0041 16.2 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus VP23 like capsid protein SLS PF14611.1 EDO17229.1 - 0.045 13.1 0.4 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator DUF726 PF05277.7 EDO17230.1 - 3.7e-138 460.1 0.6 6e-138 459.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Ribosomal_L22e PF01776.12 EDO17231.1 - 9e-43 144.8 0.9 1.1e-42 144.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Mob1_phocein PF03637.12 EDO17232.1 - 1.7e-72 242.7 1.4 3.2e-72 241.8 0.9 1.4 1 0 0 1 1 1 1 Mob1/phocein family GPCR_chapero_1 PF11904.3 EDO17232.1 - 0.2 10.7 9.5 0.29 10.2 6.6 1.1 1 0 0 1 1 1 0 GPCR-chaperone Med15 PF09606.5 EDO17232.1 - 0.82 7.7 30.2 1.2 7.2 20.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal BAF1_ABF1 PF04684.8 EDO17232.1 - 1.1 8.0 21.5 1.7 7.3 14.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF605 PF04652.11 EDO17232.1 - 3.3 7.0 16.7 4.8 6.4 11.6 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EDO17232.1 - 7.4 4.6 27.9 10 4.1 19.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 vMSA PF00695.14 EDO17232.1 - 7.9 5.5 7.3 11 5.0 5.1 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Tubulin PF00091.20 EDO17234.1 - 7.3e-70 235.1 0.0 1.1e-69 234.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDO17234.1 - 3.9e-48 162.6 0.0 7.2e-48 161.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EDO17234.1 - 0.0024 17.3 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EDO17234.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain MVL PF12151.3 EDO17234.1 - 0.013 15.1 0.0 0.037 13.6 0.0 1.9 1 0 0 1 1 1 0 Mannan-binding protein Histone PF00125.19 EDO17235.1 - 7.4e-22 77.2 0.0 9.6e-22 76.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDO17235.1 - 0.0098 15.9 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-RING_2 PF13639.1 EDO17236.1 - 3.7e-10 39.4 8.5 3.4e-09 36.3 5.9 2.2 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO17236.1 - 1.2e-08 34.8 2.7 2.4e-08 33.9 1.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EDO17236.1 - 5e-07 29.3 3.4 1.3e-06 28.0 2.3 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDO17236.1 - 6.1e-06 26.1 3.4 6.1e-06 26.1 2.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO17236.1 - 1.1e-05 25.0 7.5 6.2e-05 22.5 5.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO17236.1 - 0.00021 20.8 7.8 0.00079 19.0 5.4 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO17236.1 - 0.0012 18.5 2.6 0.0012 18.5 1.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EDO17236.1 - 0.0061 16.0 0.1 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EDO17236.1 - 0.013 15.3 0.9 0.029 14.2 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EDO17236.1 - 0.013 15.3 2.2 0.013 15.3 1.5 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING AzlD PF05437.7 EDO17236.1 - 0.017 15.0 3.2 0.019 14.8 1.3 1.8 1 1 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) zf-RING_4 PF14570.1 EDO17236.1 - 0.24 10.9 2.3 0.42 10.2 0.6 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EDO17236.1 - 0.51 9.8 6.6 0.09 12.2 1.7 1.8 2 0 0 2 2 2 0 P-11 zinc finger Amelogenin PF02948.10 EDO17236.1 - 1.3 9.6 8.7 2 9.0 6.0 1.3 1 0 0 1 1 1 0 Amelogenin RINGv PF12906.2 EDO17236.1 - 3.9 7.5 7.7 0.26 11.3 1.6 1.8 2 0 0 2 2 1 0 RING-variant domain CDP-OH_P_transf PF01066.16 EDO17239.1 - 6.6e-12 45.6 3.3 1.3e-11 44.6 2.3 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase ACOX PF01756.14 EDO17240.1 - 3e-49 166.9 0.0 9.2e-49 165.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EDO17240.1 - 5.6e-17 60.9 0.7 1.1e-16 60.0 0.5 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EDO17240.1 - 1.6e-12 47.8 0.0 4.3e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 EDO17240.1 - 0.0014 18.7 0.0 0.0047 17.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain zf-CCHC PF00098.18 EDO17241.1 - 1.8e-12 46.5 33.5 7.3e-05 22.5 2.9 5.2 5 0 0 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.1 EDO17241.1 - 1 8.9 22.3 0.65 9.5 1.4 3.8 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDO17241.1 - 2.5 7.8 35.4 0.069 12.8 0.8 5.5 4 1 1 5 5 5 0 Zinc knuckle Sec7 PF01369.15 EDO17243.1 - 8.2e-38 129.9 0.5 1.7e-37 128.9 0.4 1.5 1 0 0 1 1 1 1 Sec7 domain PHF5 PF03660.9 EDO17244.1 - 1.6e-50 169.6 12.5 1.7e-50 169.5 8.7 1.0 1 0 0 1 1 1 1 PHF5-like protein zf-RING_2 PF13639.1 EDO17245.1 - 2.7e-10 39.8 11.0 2.7e-10 39.8 7.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDO17245.1 - 6.1e-07 29.0 6.4 6.1e-07 29.0 4.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO17245.1 - 1.6e-06 27.7 10.1 1.6e-06 27.7 7.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO17245.1 - 1.1e-05 25.0 11.0 1.1e-05 25.0 7.6 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDO17245.1 - 1.5e-05 25.0 9.4 1.5e-05 25.0 6.5 2.9 2 1 1 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EDO17245.1 - 5.1e-05 23.1 10.4 5.1e-05 23.1 7.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDO17245.1 - 0.006 16.4 13.6 0.0069 16.1 2.5 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 EDO17245.1 - 0.0063 16.4 15.1 0.013 15.4 1.8 2.6 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EDO17245.1 - 0.058 13.5 20.7 0.083 13.0 4.1 3.0 2 2 1 3 3 3 0 PHD-like zinc-binding domain CK2S PF15011.1 EDO17245.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Casein Kinase 2 substrate PHD PF00628.24 EDO17245.1 - 0.39 10.4 30.6 0.38 10.4 8.7 2.5 2 0 0 2 2 2 0 PHD-finger Cofilin_ADF PF00241.15 EDO17246.1 - 1e-22 80.3 1.9 2.5e-11 43.5 0.2 2.5 2 1 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Plasmid_parti PF01672.11 EDO17246.1 - 0.019 15.3 0.6 0.1 13.0 0.0 2.5 2 0 0 2 2 2 0 Putative plasmid partition protein DUF2404 PF10296.4 EDO17247.1 - 2e-31 107.9 0.1 4.7e-31 106.7 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EDO17247.1 - 1.3e-10 41.4 2.9 1.5e-10 41.1 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EDO17247.1 - 1.1e-05 25.6 0.3 5e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain gp32 PF08804.5 EDO17247.1 - 0.0079 16.2 2.8 0.022 14.8 1.9 1.7 1 0 0 1 1 1 1 gp32 DNA binding protein like CKS PF01111.14 EDO17248.1 - 2.3e-34 117.0 0.1 3.4e-34 116.4 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DIL PF01843.14 EDO17249.1 - 1e-10 41.4 4.9 0.00021 21.1 0.1 2.7 2 0 0 2 2 2 2 DIL domain SRP54 PF00448.17 EDO17250.1 - 3.1e-80 268.2 5.1 9.4e-80 266.6 0.4 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EDO17250.1 - 2e-25 89.0 11.8 2e-25 89.0 8.2 4.6 5 0 0 5 5 5 1 Signal peptide binding domain SRP54_N PF02881.14 EDO17250.1 - 3.7e-14 52.5 2.9 1.2e-13 50.8 2.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EDO17250.1 - 6.3e-07 28.9 1.7 6.9e-06 25.6 0.3 3.2 3 1 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EDO17250.1 - 9.8e-07 28.7 0.0 5.2e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.5 EDO17250.1 - 2.3e-05 23.7 2.6 0.74 9.0 0.1 3.9 3 1 0 3 3 3 2 Signal recognition particle receptor beta subunit MobB PF03205.9 EDO17250.1 - 4.1e-05 23.2 0.0 0.00013 21.7 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EDO17250.1 - 5.1e-05 22.7 1.5 0.00015 21.1 0.1 2.5 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EDO17250.1 - 7.1e-05 22.7 0.1 0.04 13.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 EDO17250.1 - 0.0015 17.4 0.2 0.012 14.3 0.0 2.7 1 1 1 2 2 2 1 ArgK protein AAA_17 PF13207.1 EDO17250.1 - 0.0015 19.3 0.0 0.0033 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EDO17250.1 - 0.0055 16.1 0.2 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EDO17250.1 - 0.0055 16.8 0.3 0.038 14.1 0.1 2.7 2 1 0 2 2 1 1 AAA domain ATP_bind_1 PF03029.12 EDO17250.1 - 0.01 15.4 0.1 0.052 13.0 0.1 2.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 EDO17250.1 - 0.011 14.8 0.0 0.027 13.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.15 EDO17250.1 - 0.014 15.0 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 EDO17250.1 - 0.017 15.4 0.4 0.089 13.1 0.0 2.5 3 1 0 3 3 2 0 AAA domain MipZ PF09140.6 EDO17250.1 - 0.018 14.1 0.1 0.54 9.2 0.1 2.6 1 1 0 1 1 1 0 ATPase MipZ AAA_30 PF13604.1 EDO17250.1 - 0.018 14.6 0.0 0.055 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDO17250.1 - 0.036 14.0 0.2 0.17 11.8 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EDO17250.1 - 0.17 11.8 0.1 0.87 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EDO17250.1 - 0.19 10.8 4.0 0.46 9.6 0.0 3.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA PF00004.24 EDO17250.1 - 1.2 9.3 9.0 0.29 11.3 0.9 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TFIIB PF00382.14 EDO17251.1 - 1.9e-42 142.8 2.6 2.9e-27 94.2 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EDO17251.1 - 7.3e-13 47.6 0.6 1.3e-12 46.7 0.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding PH PF00169.24 EDO17252.1 - 1.3e-05 25.3 8.9 0.0014 18.8 0.1 2.9 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 EDO17252.1 - 0.00085 19.5 6.5 0.041 14.1 1.0 3.0 2 2 0 2 2 2 2 Pleckstrin homology domain YcgR_2 PF12945.2 EDO17252.1 - 0.041 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein YcgR WD40 PF00400.27 EDO17253.1 - 0.0041 16.9 1.1 0.72 9.8 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Miro PF08477.8 EDO17254.1 - 0.0011 19.4 0.1 0.031 14.7 0.0 3.1 4 0 0 4 4 4 1 Miro-like protein MMR_HSR1 PF01926.18 EDO17254.1 - 0.0024 17.8 0.0 0.2 11.6 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EDO17254.1 - 0.0064 16.4 1.5 0.0087 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain Arf PF00025.16 EDO17254.1 - 0.0093 15.2 0.2 0.022 14.0 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 EDO17254.1 - 0.028 13.7 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 Ras family Dynamin_N PF00350.18 EDO17254.1 - 0.37 10.6 3.9 3.6 7.3 1.5 2.8 2 1 0 2 2 2 0 Dynamin family ATP-synt_ab PF00006.20 EDO17255.1 - 4.9e-61 205.9 0.0 7e-61 205.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDO17255.1 - 1.8e-17 63.7 0.3 3.9e-17 62.7 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDO17255.1 - 1.2e-14 54.2 1.1 2.4e-14 53.2 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EDO17255.1 - 2.7e-05 23.9 0.7 9.4e-05 22.2 0.5 2.0 1 0 0 1 1 1 1 HAS barrel domain tRNA-synt_2b PF00587.20 EDO17256.1 - 1.8e-67 226.2 0.0 4.4e-67 224.9 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO17256.1 - 1.6e-18 66.4 0.1 4.5e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain NBP1 PF08537.5 EDO17257.1 - 0.096 11.8 0.4 0.12 11.5 0.3 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 GTP_EFTU PF00009.22 EDO17258.1 - 1.7e-57 193.8 0.0 2.4e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDO17258.1 - 2.2e-35 120.7 0.0 5.6e-35 119.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDO17258.1 - 2.1e-16 59.7 1.8 2.1e-16 59.7 1.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EDO17258.1 - 0.00018 21.0 0.5 0.00018 21.0 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EDO17258.1 - 0.00068 19.5 0.1 0.0023 17.8 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Mad3_BUB1_I PF08311.7 EDO17260.1 - 1.9e-39 134.2 1.8 4.6e-39 133.0 1.3 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 EDO17260.1 - 2.2e-25 88.3 0.3 2.2e-25 88.3 0.2 2.8 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase PF00069.20 EDO17260.1 - 7.9e-20 71.0 0.1 1.6e-19 70.1 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17260.1 - 0.0035 16.4 0.0 0.0072 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17260.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Tox-REase-2 PF15646.1 EDO17260.1 - 0.2 11.5 1.3 0.57 10.0 0.0 2.3 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 FlaC_arch PF05377.6 EDO17260.1 - 3.7 7.4 9.5 3.5 7.5 0.2 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Macoilin PF09726.4 EDO17261.1 - 2.5 6.2 12.1 3.7 5.7 8.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Trs65 PF12735.2 EDO17262.1 - 5.1e-50 170.5 14.7 5.1e-50 170.5 10.2 2.2 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 Pox_A31 PF05771.6 EDO17262.1 - 0.0026 17.5 0.1 0.033 13.9 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A31 protein Clathrin_lg_ch PF01086.12 EDO17263.1 - 1.4e-53 182.1 13.6 1.6e-53 181.9 9.4 1.0 1 0 0 1 1 1 1 Clathrin light chain Phosducin PF02114.11 EDO17263.1 - 0.031 13.0 6.9 0.055 12.1 4.8 1.5 1 1 0 1 1 1 0 Phosducin DUF4404 PF14357.1 EDO17263.1 - 1.7 9.1 4.8 7.9 6.9 0.1 3.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4065 PF13274.1 EDO17263.1 - 9.1 7.0 9.5 26 5.5 6.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) DUF310 PF03750.8 EDO17264.1 - 0.065 13.4 0.9 3 8.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF310) ATP-synt_8 PF00895.15 EDO17264.1 - 0.38 10.9 5.7 12 6.1 0.3 3.3 2 0 0 2 2 2 0 ATP synthase protein 8 SH3_9 PF14604.1 EDO17265.1 - 1.3e-07 31.0 0.2 3.5e-07 29.7 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EDO17265.1 - 9.2e-07 28.1 0.1 3.1e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EDO17265.1 - 1.1e-05 24.8 0.0 2.9e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain ARGLU PF15346.1 EDO17266.1 - 1 9.1 23.2 1.1 8.9 16.1 1.1 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 DUF4355 PF14265.1 EDO17266.1 - 1.6 8.6 22.1 2.5 8.0 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) BTV_NS2 PF04514.7 EDO17266.1 - 1.8 7.3 10.2 2 7.2 7.1 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HemX PF04375.9 EDO17266.1 - 1.8 7.0 10.4 2 6.9 7.2 1.0 1 0 0 1 1 1 0 HemX SpoVR PF04293.8 EDO17266.1 - 3.1 6.0 7.5 3.5 5.8 5.2 1.0 1 0 0 1 1 1 0 SpoVR like protein RRF PF01765.14 EDO17266.1 - 4.2 6.7 10.8 4.5 6.6 7.5 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Lge1 PF11488.3 EDO17266.1 - 6.4 7.0 7.5 9.9 6.4 5.2 1.5 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 DUF1764 PF08576.5 EDO17266.1 - 8.6 7.2 10.7 12 6.7 7.4 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) PS_Dcarbxylase PF02666.10 EDO17267.1 - 4.5e-50 169.7 0.0 1.1e-49 168.5 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase C2 PF00168.25 EDO17267.1 - 9.5e-15 54.2 0.7 1.7e-10 40.5 0.1 2.6 2 0 0 2 2 2 2 C2 domain DNA_pol_E_B PF04042.11 EDO17268.1 - 7.4e-42 142.9 0.2 7.4e-42 142.9 0.1 1.4 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B DUF2543 PF10820.3 EDO17268.1 - 0.25 11.3 1.4 0.63 10.0 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2543) tRNA-synt_1g PF09334.6 EDO17269.1 - 4.2e-106 354.9 2.8 9.8e-106 353.6 2.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EDO17269.1 - 2.2e-24 85.4 1.2 1e-11 43.5 0.0 4.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EDO17269.1 - 2.4e-07 30.1 0.1 0.00027 20.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EDO17269.1 - 0.0058 15.3 0.0 0.013 14.1 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (K) Yip1 PF04893.12 EDO17270.1 - 4.3e-12 45.8 13.4 6.7e-12 45.2 9.3 1.3 1 0 0 1 1 1 1 Yip1 domain Cyclin_N PF00134.18 EDO17271.1 - 5.6e-24 84.1 1.1 1.1e-23 83.1 0.8 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain MRF_C2 PF13888.1 EDO17272.1 - 0.28 10.9 2.2 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Myelin gene regulatory factor C-terminal domain 2 ETF_QO PF05187.8 EDO17273.1 - 8.6e-40 135.1 0.0 1.6e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EDO17273.1 - 3.4e-10 39.3 2.5 4.4e-05 22.5 1.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDO17273.1 - 1.3e-09 37.4 0.8 9e-05 21.4 0.7 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EDO17273.1 - 1.9e-09 36.9 0.1 8.9e-05 21.6 0.1 2.2 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 EDO17273.1 - 7e-09 35.5 0.1 2.3e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDO17273.1 - 4.8e-07 29.8 0.1 2.2e-06 27.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO17273.1 - 5.6e-07 29.8 0.9 8e-06 26.0 0.7 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EDO17273.1 - 7.6e-05 21.9 0.8 0.00055 19.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EDO17273.1 - 0.0001 21.5 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EDO17273.1 - 0.00013 20.5 0.9 0.0009 17.8 0.4 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EDO17273.1 - 0.00081 19.7 0.5 1.9 8.9 0.1 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO17273.1 - 0.0017 18.1 0.3 0.0034 17.1 0.2 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EDO17273.1 - 0.0061 15.5 0.5 0.0091 14.9 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EDO17273.1 - 0.011 14.3 0.9 0.041 12.5 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_7 PF12838.2 EDO17273.1 - 0.045 14.1 0.4 0.1 12.9 0.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Amino_oxidase PF01593.19 EDO17273.1 - 0.05 12.6 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Fer4_2 PF12797.2 EDO17273.1 - 0.13 12.2 1.0 0.34 10.9 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain COPIIcoated_ERV PF07970.7 EDO17274.1 - 1e-75 254.1 0.4 1.3e-75 253.8 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EDO17274.1 - 1.8e-30 104.7 0.0 3.3e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PX PF00787.19 EDO17275.1 - 7.7e-23 80.4 0.1 1e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 PX domain CBFD_NFYB_HMF PF00808.18 EDO17276.1 - 1.8e-21 75.9 1.4 3.1e-21 75.1 1.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDO17276.1 - 1.8e-15 56.7 0.2 2.6e-15 56.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EDO17276.1 - 0.0043 16.8 0.2 0.0078 16.0 0.1 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.12 EDO17276.1 - 0.026 14.4 0.6 0.045 13.7 0.4 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF3453 PF11935.3 EDO17277.1 - 2.2e-72 243.3 4.8 5.9e-72 241.9 3.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) GCV_H PF01597.14 EDO17278.1 - 2.8e-45 152.9 0.3 3.3e-45 152.6 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EDO17278.1 - 0.019 14.6 0.1 0.071 12.7 0.1 1.8 2 0 0 2 2 2 0 Biotin-requiring enzyme eIF2A PF08662.6 EDO17279.1 - 2.8e-26 92.4 1.2 7.9e-24 84.4 0.5 3.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EDO17279.1 - 1.9e-05 24.2 0.1 4.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO17279.1 - 0.00025 20.9 0.0 0.00061 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO17279.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EDO17279.1 - 0.25 11.2 3.8 48 4.0 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat Proteasome PF00227.21 EDO17280.1 - 3.7e-51 173.1 0.0 4.8e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO17280.1 - 9.3e-12 44.0 0.0 9.3e-12 44.0 0.0 2.0 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature DLH PF01738.13 EDO17281.1 - 3.4e-29 101.6 0.0 3.9e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EDO17281.1 - 9.1e-08 31.9 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EDO17281.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 EDO17281.1 - 0.13 12.1 0.0 5.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative lysophospholipase Zn_clus PF00172.13 EDO17282.1 - 1.2e-10 41.1 11.8 2.1e-10 40.3 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUFU_C PF12470.3 EDO17282.1 - 0.86 9.1 7.3 0.045 13.3 0.3 2.4 3 0 0 3 3 3 0 Suppressor of Fused Gli/Ci N terminal binding domain AMP-binding PF00501.23 EDO17283.1 - 8.8e-92 307.6 0.0 1.1e-91 307.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO17283.1 - 2.9e-18 66.5 0.8 1.1e-17 64.7 0.1 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain TPPII PF12580.3 EDO17283.1 - 0.046 13.0 0.1 0.98 8.6 0.0 2.2 2 0 0 2 2 2 0 Tripeptidyl peptidase II Ribosomal_L7Ae PF01248.21 EDO17284.1 - 4e-22 77.5 0.7 5e-22 77.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 EDO17284.1 - 0.0062 16.5 0.7 0.017 15.1 0.2 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF1269) DUF2622 PF11080.3 EDO17284.1 - 0.15 11.9 0.8 0.38 10.6 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2622) Kelch_3 PF13415.1 EDO17285.1 - 1e-08 35.1 1.0 0.0018 18.3 0.0 6.0 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EDO17285.1 - 1.2e-07 31.4 6.7 0.0038 16.9 0.1 5.3 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EDO17285.1 - 1.9e-06 27.7 8.2 0.072 13.0 0.0 5.3 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 EDO17285.1 - 3.1e-06 27.1 8.5 1.5 9.0 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 EDO17285.1 - 0.00053 19.4 3.5 7.4 6.2 0.0 4.2 3 0 0 3 3 3 3 Kelch motif LRR_4 PF12799.2 EDO17287.1 - 8.6e-05 22.0 57.5 0.00051 19.5 1.2 8.0 7 2 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EDO17287.1 - 3 8.2 35.7 21 5.6 0.2 9.5 7 3 1 8 8 8 0 Leucine Rich Repeat Aldedh PF00171.17 EDO17288.1 - 5.8e-179 595.2 0.6 6.6e-179 595.0 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EDO17288.1 - 0.016 13.9 0.1 0.11 11.1 0.0 2.1 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EDO17288.1 - 0.03 13.5 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) PT-VENN PF04829.8 EDO17288.1 - 0.56 9.7 3.6 1.2 8.6 0.3 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Calreticulin PF00262.13 EDO17289.1 - 2e-124 414.9 14.5 2.6e-124 414.5 10.1 1.1 1 0 0 1 1 1 1 Calreticulin family ELFV_dehydrog PF00208.16 EDO17290.1 - 5.2e-82 275.0 3.2 6.3e-82 274.8 2.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EDO17290.1 - 2e-46 156.8 0.0 4.4e-46 155.7 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF373 PF04123.8 EDO17290.1 - 0.047 12.7 0.2 0.074 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Flavodoxin_2 PF02525.12 EDO17291.1 - 3.9e-54 183.1 0.0 4.8e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EDO17291.1 - 8.8e-14 51.2 0.0 2.2e-13 50.0 0.0 1.6 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 EDO17291.1 - 3.8e-06 26.3 0.1 2.6e-05 23.6 0.0 2.3 3 0 0 3 3 3 1 Flavodoxin Fungal_trans_2 PF11951.3 EDO17292.1 - 8.7e-96 320.8 1.1 1.3e-95 320.2 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO17292.1 - 6.3e-11 41.9 7.4 1.2e-10 41.1 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HABP4_PAI-RBP1 PF04774.10 EDO17292.1 - 0.24 11.9 5.0 0.66 10.4 3.5 1.8 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family RFX1_trans_act PF04589.8 EDO17292.1 - 1.2 8.8 10.3 2.3 7.9 7.1 1.4 1 0 0 1 1 1 0 RFX1 transcription activation region PQ-loop PF04193.9 EDO17293.1 - 3.8e-19 67.9 2.5 3.8e-19 67.9 1.8 3.0 3 0 0 3 3 3 1 PQ loop repeat DUF204 PF02659.10 EDO17293.1 - 0.015 15.4 2.4 0.02 15.0 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF DUF1275 PF06912.6 EDO17293.1 - 0.052 12.7 3.2 0.041 13.0 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) DUF2029 PF09594.5 EDO17293.1 - 0.069 12.6 6.3 0.1 12.1 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) ABC2_membrane_5 PF13346.1 EDO17293.1 - 6.9 5.9 18.5 2.2 7.5 4.5 2.1 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF805 PF05656.9 EDO17293.1 - 8.7 6.1 14.6 2.2e+03 -1.6 10.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Spc97_Spc98 PF04130.8 EDO17294.1 - 4.6e-68 229.8 26.6 6.3e-68 229.4 18.4 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 EDO17295.1 - 2.4e-55 186.7 0.1 3.2e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO17295.1 - 1.5e-13 49.7 0.1 3.9e-13 48.4 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Bromodomain PF00439.20 EDO17296.1 - 9.9e-27 92.6 1.9 2.2e-26 91.6 1.3 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EDO17296.1 - 1.3e-08 34.8 0.1 3.1e-08 33.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDO17296.1 - 4.1e-08 33.1 0.0 7.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NMD3 PF04981.8 EDO17297.1 - 9.6e-75 250.7 1.7 1.5e-74 250.0 1.2 1.3 1 0 0 1 1 1 1 NMD3 family FYVE PF01363.16 EDO17297.1 - 2.8 7.9 7.1 1.8 8.5 2.4 2.3 2 0 0 2 2 2 0 FYVE zinc finger zinc_ribbon_6 PF14599.1 EDO17297.1 - 3.4 7.5 9.6 0.47 10.2 0.1 3.4 2 1 1 3 3 3 0 Zinc-ribbon Rpr2 PF04032.11 EDO17297.1 - 4.1 7.3 6.6 4.2 7.3 0.6 3.0 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain NinF PF05810.7 EDO17297.1 - 4.6 7.1 15.7 1.5 8.6 0.5 3.8 4 0 0 4 4 4 0 NinF protein DZR PF12773.2 EDO17297.1 - 6.2 6.7 8.9 5.8 6.8 3.8 2.5 2 1 1 3 3 3 0 Double zinc ribbon DEAD PF00270.24 EDO17298.1 - 1.8e-40 138.1 0.2 1.8e-39 134.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO17298.1 - 1.3e-27 95.4 0.1 2.9e-27 94.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO17298.1 - 0.0044 16.8 0.4 0.034 13.9 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Dynactin_p22 PF07426.6 EDO17298.1 - 0.01 15.1 1.9 0.046 13.0 0.0 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 Gcd10p PF04189.8 EDO17299.1 - 0.05 12.7 3.5 0.12 11.5 2.3 1.9 1 1 0 1 1 1 0 Gcd10p family Takusan PF04822.8 EDO17299.1 - 0.063 13.0 0.7 0.17 11.6 0.5 1.7 1 0 0 1 1 1 0 Takusan Syntaxin PF00804.20 EDO17299.1 - 0.13 12.4 3.0 0.41 10.8 2.1 1.9 1 1 0 1 1 1 0 Syntaxin RRM_1 PF00076.17 EDO17300.1 - 4e-30 103.2 0.5 1.5e-11 43.7 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO17300.1 - 1.7e-22 79.1 0.0 2.2e-08 33.9 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO17300.1 - 3.8e-15 55.4 0.3 0.00086 19.1 0.0 5.3 6 0 0 6 6 6 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EDO17300.1 - 0.032 14.2 0.1 4.3 7.4 0.0 3.5 3 0 0 3 3 3 0 RNA binding domain HSF_DNA-bind PF00447.12 EDO17301.1 - 2.4e-30 104.7 0.7 5.5e-30 103.6 0.5 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Mito_carr PF00153.22 EDO17302.1 - 2.1e-59 197.2 3.6 1e-20 73.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EDO17302.1 - 0.055 13.5 0.1 1.7 8.6 0.0 2.7 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family TPP_enzyme_N PF02776.13 EDO17304.1 - 4.3e-26 91.4 0.0 6.7e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDO17304.1 - 5.8e-17 61.7 0.0 1.4e-16 60.5 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EDO17304.1 - 1.4e-15 57.1 0.0 3e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Complex1_LYR PF05347.10 EDO17305.1 - 7.5e-14 51.2 0.1 9.7e-14 50.9 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDO17305.1 - 1e-10 41.6 0.1 1.2e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like RhoGAP PF00620.22 EDO17306.1 - 5.1e-40 136.5 0.4 1.2e-39 135.3 0.3 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EDO17306.1 - 1.4e-14 53.8 31.6 1.4e-08 34.6 7.2 2.5 2 0 0 2 2 2 2 LIM domain LSM PF01423.17 EDO17307.1 - 3.7e-15 55.2 0.0 4.3e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO17307.1 - 0.00042 20.1 0.0 0.00051 19.9 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Pyr_redox_3 PF13738.1 EDO17308.1 - 1.4e-05 25.2 0.0 0.075 13.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EDO17308.1 - 7e-05 22.7 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EDO17308.1 - 0.00049 19.9 0.0 0.0029 17.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDO17308.1 - 0.0014 18.5 0.0 0.01 15.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EDO17308.1 - 0.035 13.0 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EDO17308.1 - 0.08 13.0 0.0 23 5.0 0.0 2.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Borrelia_orfD PF02999.9 EDO17308.1 - 0.095 12.8 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Borrelia orf-D family Lipase_GDSL PF00657.17 EDO17309.1 - 8.5e-21 74.8 0.0 1e-20 74.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EDO17309.1 - 2.2e-16 60.5 0.0 2.7e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family BCS1_N PF08740.6 EDO17310.1 - 9e-48 162.3 0.1 1.6e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EDO17310.1 - 4.7e-23 81.8 0.0 8.5e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDO17310.1 - 3e-06 28.0 0.0 7.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO17310.1 - 0.00029 21.1 0.0 0.0017 18.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EDO17310.1 - 0.00035 20.6 0.2 0.0011 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDO17310.1 - 0.00048 20.1 0.0 0.0011 18.9 0.0 1.6 2 0 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.1 EDO17310.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDO17310.1 - 0.00077 18.5 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EDO17310.1 - 0.0011 17.9 0.0 0.002 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EDO17310.1 - 0.0017 18.4 0.0 0.0048 17.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EDO17310.1 - 0.0034 17.1 0.0 0.018 14.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EDO17310.1 - 0.004 16.5 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO17310.1 - 0.0049 16.7 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EDO17310.1 - 0.0052 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 EDO17310.1 - 0.0075 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EDO17310.1 - 0.0087 15.7 0.0 0.26 10.9 0.0 2.9 2 1 1 3 3 3 1 NACHT domain AAA_24 PF13479.1 EDO17310.1 - 0.018 14.5 0.1 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDO17310.1 - 0.021 14.9 0.0 0.054 13.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EDO17310.1 - 0.024 14.1 0.0 0.059 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EDO17310.1 - 0.031 13.9 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Miro PF08477.8 EDO17310.1 - 0.036 14.5 0.0 0.076 13.5 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein KaiC PF06745.8 EDO17310.1 - 0.039 13.0 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EDO17310.1 - 0.043 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EDO17310.1 - 0.052 13.8 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EDO17310.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EDO17310.1 - 0.076 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain MAPEG PF01124.13 EDO17310.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 MAPEG family DUF3315 PF11776.3 EDO17310.1 - 0.32 10.5 1.7 0.33 10.5 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF3315) DUF3439 PF11921.3 EDO17311.1 - 2.7 7.7 7.8 0.12 12.1 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3439) YTH PF04146.10 EDO17312.1 - 2.2e-41 140.7 0.0 3.5e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain COQ7 PF03232.8 EDO17313.1 - 5.3e-75 250.6 0.0 6.6e-75 250.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 EF-hand_7 PF13499.1 EDO17314.1 - 5.1e-27 93.8 13.8 1.9e-14 53.5 0.6 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EDO17314.1 - 7.1e-26 87.5 7.1 1.4e-07 30.2 0.6 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EDO17314.1 - 9.8e-24 81.0 1.8 1.4e-06 27.6 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EDO17314.1 - 2.8e-19 67.4 4.3 2.1e-05 23.6 0.4 4.3 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EDO17314.1 - 4.1e-19 67.9 5.6 1.5e-08 34.1 0.1 3.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EDO17314.1 - 3.4e-05 23.5 5.2 0.37 10.5 0.1 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EDO17314.1 - 0.00048 19.9 0.2 0.0038 17.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EDO17314.1 - 0.00058 19.8 1.1 0.083 12.9 0.1 3.2 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 EDO17314.1 - 0.0045 16.8 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 Plectin/S10 domain EF-hand_2 PF09068.6 EDO17314.1 - 0.027 14.5 0.1 8.8 6.4 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_10 PF14788.1 EDO17314.1 - 0.066 12.8 0.2 5.8 6.6 0.0 2.8 3 0 0 3 3 3 0 EF hand UCH PF00443.24 EDO17315.1 - 1.6e-60 204.5 3.0 3.2e-60 203.5 2.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EDO17315.1 - 1e-49 165.7 11.2 5.7e-21 73.6 0.2 5.1 4 1 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 EDO17315.1 - 7.1e-09 35.5 15.4 6.7e-05 22.4 0.8 3.1 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase GPP34 PF05719.6 EDO17316.1 - 1.4e-49 169.0 0.0 1.6e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Glyco_hydro_18 PF00704.23 EDO17317.1 - 3.1e-72 243.8 11.1 5.5e-72 243.0 7.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Sigma70_ner PF04546.8 EDO17317.1 - 0.45 10.1 6.5 0.87 9.1 4.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 EDO17317.1 - 0.51 8.2 5.7 0.9 7.3 3.9 1.4 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.5 EDO17317.1 - 0.7 10.1 11.1 1.7 8.9 7.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.6 EDO17317.1 - 0.71 9.6 7.7 1.4 8.7 5.4 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 EDO17317.1 - 4.1 6.0 16.8 6.2 5.4 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 EDO17317.1 - 7.2 6.9 17.0 22 5.4 11.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EDO17317.1 - 8.3 5.9 15.4 17 4.8 10.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EDO17317.1 - 9.4 5.3 12.4 16 4.6 8.6 1.3 1 0 0 1 1 1 0 NOA36 protein Leo1 PF04004.8 EDO17318.1 - 1e-44 152.2 0.0 1e-44 152.2 0.0 2.7 3 0 0 3 3 3 1 Leo1-like protein Profilin PF00235.14 EDO17319.1 - 4.5e-40 136.5 0.1 5e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Profilin Aldo_ket_red PF00248.16 EDO17321.1 - 2.3e-50 171.0 0.0 2.7e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kei1 PF08552.6 EDO17322.1 - 5.5e-50 169.6 16.2 3e-38 131.3 8.1 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 DUF373 PF04123.8 EDO17322.1 - 1.2 8.1 4.5 1.4 7.8 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) RIO1 PF01163.17 EDO17323.1 - 8.9e-71 237.1 0.4 8.9e-71 237.1 0.3 2.5 3 1 0 3 3 3 1 RIO1 family APH PF01636.18 EDO17323.1 - 0.016 14.9 0.1 1.2 8.8 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Nop14 PF04147.7 EDO17323.1 - 0.018 12.9 34.0 0.031 12.2 23.5 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EDO17323.1 - 0.12 10.3 28.4 0.22 9.5 19.7 1.3 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 EDO17323.1 - 0.21 11.1 33.8 0.49 9.9 23.4 1.7 1 0 0 1 1 1 0 YL1 nuclear protein EBV-NA3 PF05009.7 EDO17323.1 - 3.5 6.8 9.4 8.2 5.5 6.5 1.6 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) WD40 PF00400.27 EDO17324.1 - 7e-38 127.1 7.2 4.7e-08 32.6 0.0 7.2 6 1 0 6 6 6 6 WD domain, G-beta repeat PD40 PF07676.7 EDO17324.1 - 0.066 12.9 0.1 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat AAA PF00004.24 EDO17325.1 - 4e-41 140.2 0.2 1.1e-40 138.9 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EDO17325.1 - 2.4e-05 24.4 0.3 0.012 15.6 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EDO17325.1 - 3.9e-05 23.6 0.5 0.00018 21.4 0.0 2.3 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EDO17325.1 - 7.3e-05 22.5 0.1 0.00039 20.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EDO17325.1 - 0.00034 20.7 0.2 0.0077 16.3 0.2 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDO17325.1 - 0.00064 18.8 0.0 0.0014 17.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 EDO17325.1 - 0.0055 15.9 0.2 0.029 13.5 0.1 2.0 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 EDO17325.1 - 0.0062 16.4 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO17325.1 - 0.0082 16.9 0.2 0.032 15.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO17325.1 - 0.0096 15.6 0.1 0.025 14.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EDO17325.1 - 0.0099 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.8 EDO17325.1 - 0.012 14.5 0.0 0.024 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EDO17325.1 - 0.013 14.6 0.1 0.037 13.1 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EDO17325.1 - 0.028 13.9 0.3 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF1192 PF06698.6 EDO17325.1 - 0.032 14.0 2.2 0.086 12.6 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) AAA_14 PF13173.1 EDO17325.1 - 0.034 14.0 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDO17325.1 - 0.04 13.3 0.7 0.4 10.0 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EDO17325.1 - 0.068 12.7 1.1 0.13 11.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain ThylakoidFormat PF11264.3 EDO17325.1 - 0.074 12.6 5.0 0.084 12.4 2.5 1.8 2 0 0 2 2 2 0 Thylakoid formation protein ABC_tran PF00005.22 EDO17325.1 - 0.093 13.0 0.4 17 5.7 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Macoilin PF09726.4 EDO17325.1 - 0.14 10.3 1.8 0.21 9.8 1.2 1.2 1 0 0 1 1 1 0 Transmembrane protein TcpE PF12648.2 EDO17326.1 - 0.48 10.5 4.6 0.27 11.3 0.8 1.9 2 0 0 2 2 2 0 TcpE family Abhydrolase_6 PF12697.2 EDO17327.1 - 1.8e-22 80.3 0.0 2.4e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO17327.1 - 1.4e-13 50.9 0.0 1.2e-11 44.6 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO17327.1 - 5.4e-06 26.2 0.0 1.4e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EDO17327.1 - 0.002 18.4 0.0 0.0033 17.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EDO17327.1 - 0.0028 17.2 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein FSH1 PF03959.8 EDO17327.1 - 0.0041 16.5 0.0 9.9 5.5 0.0 3.1 2 1 0 3 3 3 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 EDO17327.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase BAAT_C PF08840.6 EDO17327.1 - 0.074 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF912 PF06024.7 EDO17328.1 - 0.0029 17.6 0.0 0.0029 17.6 0.0 3.7 5 0 0 5 5 5 1 Nucleopolyhedrovirus protein of unknown function (DUF912) PWI PF01480.12 EDO17329.1 - 0.00036 20.5 1.2 0.0023 18.0 0.8 2.4 1 0 0 1 1 1 1 PWI domain PBP1_TM PF14812.1 EDO17329.1 - 0.013 15.7 2.9 0.064 13.5 2.0 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cyc-maltodext_C PF10438.4 EDO17329.1 - 1 9.4 8.7 0.11 12.6 0.6 3.2 3 0 0 3 3 3 0 Cyclo-malto-dextrinase C-terminal domain CENP-B_dimeris PF09026.5 EDO17329.1 - 3.5 7.9 10.3 0.26 11.5 3.1 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HABP4_PAI-RBP1 PF04774.10 EDO17330.1 - 3.6e-05 24.2 0.3 4.6e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family RE_LlaJI PF09563.5 EDO17330.1 - 0.0056 15.4 0.0 0.0062 15.2 0.0 1.1 1 0 0 1 1 1 1 LlaJI restriction endonuclease CTP_transf_2 PF01467.21 EDO17331.1 - 4.3e-16 59.3 0.1 7.5e-13 48.8 0.0 2.5 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EDO17331.1 - 0.019 14.5 0.1 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 FAD synthetase ALAD PF00490.16 EDO17331.1 - 0.02 13.8 0.1 0.041 12.7 0.1 1.4 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase Prp18 PF02840.10 EDO17332.1 - 2.1e-34 118.4 4.2 2.2e-34 118.3 1.1 2.2 1 1 1 2 2 2 1 Prp18 domain UPF0147 PF03685.8 EDO17332.1 - 0.023 14.5 0.7 0.072 12.9 0.5 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) TFIIF_beta PF02270.10 EDO17333.1 - 4.2e-94 315.3 16.1 7.4e-94 314.5 11.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Adeno_E1B_19K PF01691.11 EDO17333.1 - 0.08 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Ribosomal_L38e PF01781.13 EDO17334.1 - 2.4e-27 94.4 2.3 2.8e-27 94.2 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Pex24p PF06398.6 EDO17335.1 - 7.3e-42 143.4 9.4 1.1e-41 142.8 6.5 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Cullin PF00888.17 EDO17336.1 - 2.4e-95 320.2 44.1 3.7e-95 319.6 30.5 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EDO17336.1 - 1.4e-15 56.8 7.3 1.5e-15 56.7 2.6 3.1 3 0 0 3 3 3 1 Cullin protein neddylation domain Myb_DNA-bind_6 PF13921.1 EDO17337.1 - 6.1 7.0 10.2 1.1 9.4 0.1 3.6 3 0 0 3 3 3 0 Myb-like DNA-binding domain AIP3 PF03915.8 EDO17338.1 - 7.2e-152 506.1 17.5 7.2e-152 506.1 12.1 3.2 2 1 1 3 3 3 1 Actin interacting protein 3 Trypan_PARP PF05887.6 EDO17338.1 - 9.9 5.9 10.1 23 4.8 7.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Telomerase_RBD PF12009.3 EDO17339.1 - 1.4e-30 106.0 4.7 1.4e-30 106.0 3.3 2.7 3 0 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EDO17339.1 - 2.5e-11 43.3 1.1 2.5e-11 43.3 0.8 3.4 3 1 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cnl2_NKP2 PF09447.5 EDO17340.1 - 0.00076 19.1 1.2 0.0015 18.1 0.2 2.1 2 0 0 2 2 2 1 Cnl2/NKP2 family protein Prominin PF05478.6 EDO17340.1 - 0.0075 13.8 2.7 0.0078 13.8 1.9 1.1 1 0 0 1 1 1 1 Prominin DUF768 PF05589.6 EDO17340.1 - 0.031 14.2 1.5 0.7 9.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF768) LXG PF04740.7 EDO17340.1 - 0.051 13.3 10.5 0.076 12.7 7.2 1.4 1 1 0 1 1 1 0 LXG domain of WXG superfamily Mst1_SARAH PF11629.3 EDO17340.1 - 0.45 10.3 2.4 1.9 8.4 0.2 2.9 2 1 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF342 PF03961.8 EDO17340.1 - 1.2 7.4 7.1 3.7 5.8 4.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF848 PF05852.6 EDO17340.1 - 1.6 8.5 7.1 3.2 7.5 4.9 1.8 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1664 PF07889.7 EDO17340.1 - 4.5 7.0 6.1 13 5.6 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 EDO17340.1 - 4.9 7.3 12.0 0.7 10.0 1.9 2.4 1 1 1 2 2 2 0 Syntaxin SNF5 PF04855.7 EDO17341.1 - 9.1e-65 218.5 3.2 3.7e-40 137.9 0.0 3.0 2 2 1 3 3 3 2 SNF5 / SMARCB1 / INI1 EF1_GNE PF00736.14 EDO17342.1 - 7.4e-32 108.9 2.0 7.4e-32 108.9 1.4 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EDO17342.1 - 3.1e-13 49.5 4.2 3.1e-13 49.5 2.9 2.7 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region DUF3752 PF12572.3 EDO17342.1 - 0.091 12.8 0.4 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) GST_C_3 PF14497.1 EDO17342.1 - 0.091 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DNA_pol3_a_NII PF11490.3 EDO17342.1 - 0.39 10.3 2.7 0.51 9.9 0.1 2.0 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Vps8 PF12816.2 EDO17343.1 - 2.7e-58 196.4 3.6 2.7e-58 196.4 2.5 3.1 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_2 PF13639.1 EDO17343.1 - 0.0027 17.5 2.0 0.0027 17.5 1.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EDO17343.1 - 0.021 14.4 8.0 0.068 12.8 5.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.27 EDO17343.1 - 0.05 13.5 0.8 0.27 11.1 0.1 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-RING_UBOX PF13445.1 EDO17343.1 - 0.068 12.9 4.3 0.069 12.8 1.2 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 EDO17343.1 - 0.13 12.3 7.6 0.61 10.2 5.3 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EDO17343.1 - 0.28 11.0 2.8 1.1 9.2 1.9 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EDO17343.1 - 0.88 9.3 10.3 7.3 6.4 7.3 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDO17343.1 - 0.89 9.6 10.1 0.021 14.8 1.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EDO17343.1 - 6.7 6.4 8.5 0.47 10.1 1.5 2.2 2 0 0 2 2 2 0 PHD-finger N6-adenineMlase PF10237.4 EDO17344.1 - 5.1e-57 192.0 1.0 3.7e-55 186.0 0.7 2.1 1 1 0 1 1 1 1 Probable N6-adenine methyltransferase Adap_comp_sub PF00928.16 EDO17345.1 - 4.2e-87 291.5 0.7 5.3e-87 291.2 0.5 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EDO17345.1 - 2.5e-06 27.2 1.9 3.8e-06 26.6 0.9 1.6 1 1 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EDO17345.1 - 0.0009 18.5 0.0 0.007 15.5 0.0 2.2 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain AhpC-TSA PF00578.16 EDO17346.1 - 1.9e-28 98.6 0.3 1e-27 96.2 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EDO17346.1 - 1.2e-17 63.8 0.0 2.2e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EDO17346.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme DUF1644 PF07800.7 EDO17346.1 - 0.41 10.4 1.9 0.47 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) NAD_binding_8 PF13450.1 EDO17347.1 - 6.8e-12 45.2 0.0 1.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EDO17347.1 - 2e-06 27.1 0.0 1.1e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EDO17347.1 - 0.00057 19.6 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EDO17347.1 - 0.00066 18.6 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EDO17347.1 - 0.0017 18.6 0.1 0.077 13.4 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDO17347.1 - 0.0019 18.0 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO17347.1 - 0.0029 17.6 0.0 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDO17347.1 - 0.0082 15.2 0.0 0.027 13.5 0.0 1.8 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EDO17347.1 - 0.016 14.1 0.3 13 4.5 0.0 3.1 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EDO17347.1 - 0.15 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HMG_box PF00505.14 EDO17348.1 - 6.8e-14 51.8 5.3 5.5e-13 48.9 3.7 2.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO17348.1 - 0.00033 20.9 0.9 0.0013 19.0 0.6 2.0 1 1 0 1 1 1 1 HMG-box domain Proteasome PF00227.21 EDO17349.1 - 1.4e-45 154.9 0.0 1.7e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO17349.1 - 9.3e-13 47.2 0.2 1.9e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.11 EDO17349.1 - 0.024 14.3 0.0 8.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK DUF1250 PF06855.7 EDO17349.1 - 0.14 11.7 0.1 0.64 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1250) DnaJ PF00226.26 EDO17351.1 - 6.9e-17 60.9 0.1 6.9e-17 60.9 0.1 2.6 3 0 0 3 3 3 1 DnaJ domain Methyltrn_RNA_3 PF02598.12 EDO17352.1 - 4.2e-102 341.4 1.2 5.8e-102 340.9 0.8 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase MVIN PF03023.9 EDO17352.1 - 0.04 12.3 0.0 0.057 11.8 0.0 1.1 1 0 0 1 1 1 0 MviN-like protein Glyco_hydro_17 PF00332.13 EDO17353.1 - 1.5e-72 244.2 0.6 1.8e-72 244.0 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 ABC_membrane PF00664.18 EDO17354.1 - 6e-73 245.6 37.9 1.1e-40 139.8 9.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDO17354.1 - 1.4e-49 167.8 6.6 6.8e-31 107.3 0.1 3.5 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EDO17354.1 - 1.4e-10 40.8 4.0 9.3e-05 21.7 0.2 4.5 1 1 2 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDO17354.1 - 3.7e-08 32.7 1.5 0.0017 17.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EDO17354.1 - 4.9e-08 33.2 0.6 4.9e-08 33.2 0.4 5.9 6 1 0 6 6 4 1 AAA domain AAA_17 PF13207.1 EDO17354.1 - 3.3e-06 27.9 0.0 0.12 13.1 0.0 3.4 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EDO17354.1 - 1.6e-05 23.9 0.0 0.015 14.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 EDO17354.1 - 5.3e-05 22.4 0.3 0.13 11.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EDO17354.1 - 0.00014 21.4 4.1 0.19 11.2 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EDO17354.1 - 0.00015 21.7 0.1 0.059 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EDO17354.1 - 0.00019 21.3 1.2 0.22 11.4 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EDO17354.1 - 0.00024 20.2 0.0 0.041 12.9 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 EDO17354.1 - 0.00046 20.3 4.5 1.2 9.2 0.1 3.5 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 EDO17354.1 - 0.00052 20.5 0.3 1.2 9.6 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein NTPase_1 PF03266.10 EDO17354.1 - 0.0009 18.9 0.4 0.95 9.1 0.1 2.8 2 0 0 2 2 2 1 NTPase AAA_25 PF13481.1 EDO17354.1 - 0.0029 17.0 0.3 1.4 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 EDO17354.1 - 0.0036 16.8 0.1 2.8 7.3 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EDO17354.1 - 0.0094 16.3 32.1 0.046 14.0 7.4 4.6 4 2 0 4 4 3 2 AAA domain AAA_5 PF07728.9 EDO17354.1 - 0.01 15.5 1.6 6.9 6.4 0.1 3.9 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 EDO17354.1 - 0.012 15.1 1.3 5.5 6.4 0.1 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 EDO17354.1 - 0.014 15.3 0.7 0.47 10.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EDO17354.1 - 0.016 14.7 0.2 4.2 6.8 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain cobW PF02492.14 EDO17354.1 - 0.016 14.6 1.1 0.54 9.6 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EDO17354.1 - 0.023 14.6 0.8 3.7 7.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EDO17354.1 - 0.026 14.3 4.8 7.6 6.3 0.0 4.0 4 0 0 4 4 4 0 Dynamin family AAA_19 PF13245.1 EDO17354.1 - 0.026 14.2 0.1 0.2 11.4 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EDO17354.1 - 0.029 14.5 0.5 1.2 9.3 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EDO17354.1 - 0.031 13.7 0.0 4.8 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EDO17354.1 - 0.041 13.2 0.7 5 6.5 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein UPF0079 PF02367.12 EDO17354.1 - 0.048 13.2 0.5 0.35 10.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EDO17354.1 - 0.05 12.7 0.5 6.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 EDO17354.1 - 0.063 12.0 0.5 0.39 9.4 0.1 2.1 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 EDO17354.1 - 0.093 12.1 0.3 1.9 7.9 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 EDO17354.1 - 0.1 11.1 2.1 3.5 6.1 0.1 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 EDO17354.1 - 0.13 12.4 2.5 19 5.4 0.0 3.6 4 0 0 4 4 2 0 RNA helicase DUF87 PF01935.12 EDO17354.1 - 0.13 12.0 0.1 0.13 12.0 0.1 2.7 4 0 0 4 4 2 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 EDO17354.1 - 0.16 11.4 2.6 2.6 7.5 0.1 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EDO17354.1 - 5.4 7.3 20.3 0.32 11.2 0.1 4.2 6 0 0 6 6 3 0 AAA domain Dus PF01207.12 EDO17355.1 - 3.7e-55 186.9 0.0 1.7e-54 184.7 0.0 1.9 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) PRK PF00485.13 EDO17356.1 - 6.1e-63 211.8 0.0 8.9e-63 211.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EDO17356.1 - 1.4e-37 128.9 0.1 2e-37 128.4 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EDO17356.1 - 2.6e-09 37.9 0.2 1.1e-08 35.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO17356.1 - 2.4e-07 31.1 0.0 1.1e-06 29.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDO17356.1 - 0.0013 17.8 0.0 0.0033 16.5 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin CPT PF07931.7 EDO17356.1 - 0.0024 17.5 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EDO17356.1 - 0.035 13.9 0.0 0.082 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain OB_NTP_bind PF07717.11 EDO17357.1 - 3e-18 65.7 0.1 1.4e-17 63.5 0.1 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EDO17357.1 - 6.6e-16 58.1 0.0 1.9e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDO17357.1 - 6.6e-14 51.5 0.0 1.6e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO17357.1 - 2e-06 27.4 0.2 2e-06 27.4 0.2 3.8 4 0 0 4 4 4 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO17357.1 - 1.1e-05 25.5 1.7 3.3e-05 24.0 0.1 2.6 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EDO17357.1 - 8.9e-05 21.5 0.4 0.00037 19.4 0.1 2.0 1 1 0 2 2 2 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EDO17357.1 - 0.0046 16.7 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ABC_tran PF00005.22 EDO17357.1 - 0.019 15.2 0.6 0.15 12.3 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 EDO17357.1 - 0.037 13.7 0.2 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EDO17357.1 - 0.046 13.5 8.5 2.3 8.0 0.0 3.6 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EDO17357.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glyoxalase PF00903.20 EDO17358.1 - 3e-32 111.2 0.0 4.7e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EDO17358.1 - 2e-27 95.9 0.0 2.8e-13 50.4 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EDO17358.1 - 5.2e-13 48.9 0.0 3e-07 30.4 0.0 3.0 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EDO17358.1 - 0.00014 21.7 0.0 0.043 13.7 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.1 EDO17358.1 - 0.0024 17.5 0.1 0.77 9.4 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal PFK PF00365.15 EDO17359.1 - 1.5e-160 532.7 4.8 2e-118 394.4 0.2 2.4 3 0 0 3 3 3 2 Phosphofructokinase Glyoxalase_2 PF12681.2 EDO17359.1 - 0.093 13.3 0.0 0.28 11.7 0.0 1.9 1 0 0 1 1 1 0 Glyoxalase-like domain Porin_3 PF01459.17 EDO17360.1 - 1.4e-83 280.3 0.2 1.7e-83 280.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin ERG2_Sigma1R PF04622.7 EDO17361.1 - 4.9e-90 300.5 1.3 5.7e-90 300.3 0.9 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Autophagy_N PF03986.8 EDO17362.1 - 8.9e-42 142.3 0.9 2.1e-41 141.1 0.0 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EDO17362.1 - 1.9e-21 76.0 0.7 3.8e-21 75.0 0.1 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EDO17362.1 - 9.7e-15 53.3 0.6 1.8e-14 52.4 0.4 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Cyclin_N PF00134.18 EDO17363.1 - 2.3e-32 111.2 0.0 5.3e-32 110.0 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Takusan PF04822.8 EDO17363.1 - 0.056 13.2 2.6 0.2 11.4 0.4 2.6 2 0 0 2 2 2 0 Takusan Ribosomal_L36e PF01158.13 EDO17365.1 - 3.1e-36 123.2 4.2 3.5e-36 123.1 2.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e HHH_2 PF12826.2 EDO17365.1 - 0.061 13.2 0.1 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 Helix-hairpin-helix motif Ribosomal_L28 PF00830.14 EDO17366.1 - 1.5e-21 75.9 2.0 3.6e-21 74.7 1.4 1.7 1 0 0 1 1 1 1 Ribosomal L28 family Helicase_Sgs1 PF11408.3 EDO17367.1 - 2.3e-37 126.6 0.1 5.8e-37 125.3 0.1 1.8 1 0 0 1 1 1 1 Sgs1 RecQ helicase RQC PF09382.5 EDO17367.1 - 2.2e-24 85.2 2.0 2.9e-24 84.8 0.3 2.0 2 0 0 2 2 2 1 RQC domain DEAD PF00270.24 EDO17367.1 - 3.2e-24 85.3 0.1 9.3e-23 80.5 0.0 2.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO17367.1 - 1.5e-21 76.0 0.1 4.3e-18 64.9 0.0 3.2 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_34 PF13872.1 EDO17367.1 - 0.025 13.3 0.0 0.37 9.5 0.0 2.2 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 HRDC PF00570.18 EDO17367.1 - 0.097 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 HRDC domain WD40 PF00400.27 EDO17368.1 - 3.7e-21 74.1 14.6 1.2e-08 34.4 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Rhomboid PF01694.17 EDO17369.1 - 3.7e-17 62.7 15.5 3.7e-17 62.7 10.7 1.8 2 0 0 2 2 2 1 Rhomboid family DUF2075 PF09848.4 EDO17370.1 - 2.6e-105 352.2 0.1 3.3e-105 351.9 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EDO17370.1 - 5.8e-11 42.6 0.1 1.7e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EDO17370.1 - 6.8e-05 23.0 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EDO17370.1 - 0.00013 21.8 0.0 0.077 12.8 0.0 2.3 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_15 PF13175.1 EDO17370.1 - 0.00035 19.7 0.5 0.0014 17.7 0.0 2.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.1 EDO17370.1 - 0.00051 20.0 0.0 0.0015 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EDO17370.1 - 0.0013 19.0 0.3 0.2 11.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EDO17370.1 - 0.0018 18.1 0.1 0.0046 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDO17370.1 - 0.0022 17.6 0.1 0.019 14.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDO17370.1 - 0.0032 17.4 0.2 0.0089 15.9 0.0 1.8 2 0 0 2 2 1 1 50S ribosome-binding GTPase T2SE PF00437.15 EDO17370.1 - 0.0067 15.3 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein PIF1 PF05970.9 EDO17370.1 - 0.013 14.4 0.1 0.082 11.8 0.0 2.2 2 1 0 2 2 2 0 PIF1-like helicase Arch_ATPase PF01637.13 EDO17370.1 - 0.034 13.8 0.7 0.16 11.6 0.5 2.2 1 1 0 1 1 1 0 Archaeal ATPase Adeno_IVa2 PF02456.10 EDO17370.1 - 0.053 12.1 0.0 0.089 11.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Bac_DnaA PF00308.13 EDO17370.1 - 0.055 13.1 0.3 0.35 10.4 0.1 2.2 3 0 0 3 3 3 0 Bacterial dnaA protein Zds_C PF08632.5 EDO17370.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term ABC_tran PF00005.22 EDO17370.1 - 0.14 12.4 0.6 0.34 11.1 0.1 2.0 2 1 0 2 2 2 0 ABC transporter NTPase_1 PF03266.10 EDO17370.1 - 0.19 11.4 1.1 8.6 6.0 0.1 3.2 2 1 0 2 2 2 0 NTPase UAA PF08449.6 EDO17371.1 - 8.8e-77 257.9 18.4 1e-76 257.8 12.7 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EDO17371.1 - 7.7e-09 35.3 11.0 7.7e-09 35.3 7.6 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EDO17371.1 - 5.3e-07 29.7 11.6 5.3e-07 29.7 8.0 3.2 3 0 0 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.10 EDO17371.1 - 5.3e-06 25.7 6.8 0.0077 15.3 0.5 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EDO17371.1 - 0.001 19.2 24.7 0.016 15.4 7.8 2.9 3 0 0 3 3 3 2 Multidrug resistance efflux transporter DUF4500 PF14937.1 EDO17371.1 - 0.27 11.0 2.5 0.35 10.7 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4500) RINGv PF12906.2 EDO17373.1 - 0.00075 19.4 6.8 0.0016 18.4 4.7 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EDO17373.1 - 0.32 10.8 10.9 0.081 12.7 3.5 2.4 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.3 EDO17373.1 - 5.9 6.9 10.9 10 6.1 4.4 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain RasGAP_C PF03836.10 EDO17374.1 - 4.9e-32 110.5 1.5 4.9e-32 110.5 1.0 2.5 2 0 0 2 2 2 1 RasGAP C-terminus RasGAP PF00616.14 EDO17374.1 - 4.9e-21 75.2 4.3 4.9e-21 75.2 3.0 2.9 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EDO17374.1 - 2e-15 54.9 21.3 0.0026 17.2 0.5 9.9 10 0 0 10 10 10 6 IQ calmodulin-binding motif CH PF00307.26 EDO17374.1 - 3.8e-07 30.1 0.1 6.9e-06 26.0 0.0 3.1 3 0 0 3 3 3 1 Calponin homology (CH) domain DivIC PF04977.10 EDO17374.1 - 0.12 11.8 9.3 1.6 8.2 0.5 3.7 4 0 0 4 4 4 0 Septum formation initiator CAP_C PF08603.6 EDO17375.1 - 3.4 6.9 8.4 8.4 5.7 0.3 2.9 2 1 1 3 3 3 0 Adenylate cyclase associated (CAP) C terminal TIP49 PF06068.8 EDO17376.1 - 3e-178 592.5 5.3 3.6e-178 592.3 3.7 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EDO17376.1 - 5.9e-08 32.9 2.7 4.6e-05 23.6 0.1 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EDO17376.1 - 3.8e-07 29.3 2.7 0.00097 18.2 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EDO17376.1 - 1.4e-05 25.2 0.2 0.036 14.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain DnaB_C PF03796.10 EDO17376.1 - 3.2e-05 22.9 0.1 6.9e-05 21.8 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EDO17376.1 - 9.4e-05 22.4 0.0 0.0011 18.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EDO17376.1 - 0.00063 19.6 0.0 2.4 8.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EDO17376.1 - 0.0021 17.2 0.6 0.061 12.4 0.2 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EDO17376.1 - 0.0047 16.6 0.1 0.68 9.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EDO17376.1 - 0.0075 15.6 0.2 0.016 14.5 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EDO17376.1 - 0.017 15.0 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO17376.1 - 0.019 15.2 0.0 0.054 13.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDO17376.1 - 0.046 13.4 0.2 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain TFX_C PF14601.1 EDO17376.1 - 0.05 13.4 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term Sipho_tail PF05709.6 EDO17376.1 - 0.054 12.6 0.1 0.1 11.7 0.1 1.5 1 0 0 1 1 1 0 Phage tail protein Sigma54_activat PF00158.21 EDO17376.1 - 0.063 12.7 0.2 8.8 5.7 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.1 EDO17376.1 - 0.13 12.1 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP-synt_C PF00137.16 EDO17377.1 - 2.6e-26 91.2 29.3 3.5e-13 49.2 3.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 EDO17377.1 - 0.011 15.2 1.3 0.011 15.2 0.9 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Mis14 PF08641.7 EDO17378.1 - 2.1e-15 57.0 1.9 2.1e-15 57.0 1.3 2.4 2 1 0 2 2 2 1 Kinetochore protein Mis14 like IFT57 PF10498.4 EDO17378.1 - 0.36 9.5 7.1 0.11 11.1 2.5 1.7 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.4 EDO17378.1 - 0.42 10.7 3.2 2.2 8.4 1.0 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 EDO17378.1 - 0.7 9.6 6.0 0.79 9.4 0.1 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-C2H2 PF00096.21 EDO17379.1 - 1.5e-08 34.5 14.3 8.8e-05 22.6 0.9 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO17379.1 - 1.6e-08 34.3 9.8 0.00093 19.3 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO17379.1 - 1.7e-08 34.3 10.8 1.7e-08 34.3 1.5 3.1 3 0 0 3 3 3 1 Zinc-finger double domain Mucin PF01456.12 EDO17379.1 - 0.002 17.8 12.1 0.002 17.8 8.4 2.1 2 1 0 2 2 2 1 Mucin-like glycoprotein MutS_IV PF05190.13 EDO17379.1 - 0.022 14.9 0.6 0.039 14.1 0.4 1.3 1 0 0 1 1 1 0 MutS family domain IV zf-met PF12874.2 EDO17379.1 - 0.047 13.9 3.6 0.084 13.1 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Macoilin PF09726.4 EDO17379.1 - 1.2 7.3 9.3 1.4 7.1 6.4 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-C2H2_6 PF13912.1 EDO17379.1 - 1.5 8.8 5.9 0.15 11.9 0.7 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1908 PF08926.6 EDO17379.1 - 3.6 6.2 7.6 11 4.7 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) DUF3446 PF11928.3 EDO17379.1 - 8.9 6.5 20.4 3.6 7.8 7.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Mito_carr PF00153.22 EDO17381.1 - 8.7e-53 176.0 5.5 5.6e-20 70.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein P_gingi_FimA PF06321.6 EDO17381.1 - 0.036 13.2 0.0 0.11 11.6 0.0 1.6 1 1 1 2 2 2 0 Major fimbrial subunit protein (FimA) Biotin_lipoyl PF00364.17 EDO17382.1 - 1.5e-19 69.3 0.6 3.1e-19 68.3 0.4 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 EDO17382.1 - 0.00082 18.9 3.0 0.22 11.2 0.1 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like E3_binding PF02817.12 EDO17382.1 - 0.0024 17.4 0.0 0.0066 16.0 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain ATP-sulfurylase PF01747.12 EDO17383.1 - 3.5e-87 291.2 0.0 4.7e-87 290.8 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EDO17383.1 - 4.6e-48 162.6 0.0 6.9e-48 162.0 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Gp_dh_C PF02800.15 EDO17384.1 - 9.8e-75 249.2 0.1 1.4e-74 248.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EDO17384.1 - 1.3e-59 200.5 1.1 1.6e-59 200.1 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EDO17384.1 - 0.0022 17.8 0.1 0.0073 16.2 0.1 2.0 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Memo PF01875.12 EDO17385.1 - 1.6e-85 286.3 0.0 2e-85 285.9 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein Glyco_hydro_16 PF00722.16 EDO17386.1 - 5.9e-47 159.3 0.5 5.9e-47 159.3 0.3 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 DNA_pol_viral_N PF00242.12 EDO17386.1 - 0.53 9.2 18.7 0.76 8.7 13.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain RNA_pol_Rpb4 PF03874.11 EDO17387.1 - 2.7e-33 114.4 8.1 3.3e-33 114.1 5.6 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Erf4 PF10256.4 EDO17387.1 - 1.5 8.6 4.4 0.46 10.3 0.4 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family VTC PF09359.5 EDO17388.1 - 6.3e-102 340.3 0.1 1.1e-101 339.6 0.1 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EDO17388.1 - 4.1e-21 75.9 13.3 6.5e-10 39.2 0.6 3.8 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EDO17388.1 - 6.4e-07 29.4 5.9 1.1e-06 28.7 3.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.15 EDO17388.1 - 0.019 14.5 4.4 0.029 13.9 3.1 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 LXG PF04740.7 EDO17388.1 - 0.48 10.1 4.6 2.9 7.6 0.0 2.7 3 0 0 3 3 3 0 LXG domain of WXG superfamily Cpn60_TCP1 PF00118.19 EDO17389.1 - 3.2e-151 504.2 1.9 3.6e-151 504.0 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sad1_UNC PF07738.8 EDO17390.1 - 2.7e-08 33.6 0.3 6.8e-06 25.9 0.2 2.8 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Baculo_PEP_C PF04513.7 EDO17390.1 - 0.0052 16.6 1.9 0.0052 16.6 1.3 2.8 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3675 PF12428.3 EDO17390.1 - 0.43 10.8 1.5 1.2 9.4 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3675) UPF0118 PF01594.11 EDO17390.1 - 3.1 6.7 5.1 1.2 7.9 1.1 2.0 1 1 0 2 2 2 0 Domain of unknown function DUF20 Bot1p PF12298.3 EDO17391.1 - 1.8e-63 213.5 0.2 2.4e-63 213.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF2316 PF10078.4 EDO17391.1 - 0.046 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) HTH_37 PF13744.1 EDO17391.1 - 0.16 11.8 0.3 0.35 10.6 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain WD40_alt PF14077.1 EDO17391.1 - 0.29 10.7 1.3 2.8 7.6 0.1 2.5 2 0 0 2 2 2 0 Alternative WD40 repeat motif SH3_2 PF07653.12 EDO17392.1 - 4.8e-09 35.5 0.0 1.3e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDO17392.1 - 5.7e-08 32.0 0.3 5.7e-08 32.0 0.2 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EDO17392.1 - 5.1e-07 29.1 0.2 5.1e-07 29.1 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain PseudoU_synth_2 PF00849.17 EDO17393.1 - 5e-27 94.7 0.0 7.9e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase GFA PF04828.9 EDO17393.1 - 0.08 12.8 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Sox_N PF12444.3 EDO17394.1 - 0.13 13.3 0.1 1.9 9.6 0.0 2.3 2 0 0 2 2 2 0 Sox developmental protein N terminal TFIIE_beta PF02186.10 EDO17395.1 - 1.3e-19 69.9 0.6 3e-19 68.7 0.4 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF1987 PF09345.5 EDO17395.1 - 0.038 13.8 0.3 0.085 12.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) CRAL_TRIO PF00650.15 EDO17396.1 - 3.8e-29 101.2 0.4 6.8e-29 100.3 0.1 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDO17396.1 - 1.5e-08 34.6 2.4 1.9e-08 34.3 0.6 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Pkinase PF00069.20 EDO17397.1 - 1.8e-51 174.7 0.0 6.2e-51 173.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17397.1 - 2.1e-20 72.9 0.0 3.6e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO17397.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RNA_pol_Rpb4 PF03874.11 EDO17398.1 - 2e-35 121.3 11.6 1.4e-34 118.5 8.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb4 Tom37_C PF11801.3 EDO17398.1 - 0.012 15.5 4.0 0.012 15.5 2.8 1.9 1 1 1 2 2 2 0 Tom37 C-terminal domain SPX PF03105.14 EDO17398.1 - 0.1 12.3 11.3 0.12 12.1 7.8 1.3 1 0 0 1 1 1 0 SPX domain Rtf2 PF04641.7 EDO17398.1 - 0.97 8.5 10.6 1.4 8.1 7.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger PBP1_TM PF14812.1 EDO17398.1 - 1.9 8.8 9.4 2.8 8.3 4.9 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1168 PF06658.7 EDO17398.1 - 2.2 7.8 17.8 0.24 10.9 6.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) CDC45 PF02724.9 EDO17398.1 - 4.2 5.2 13.2 5 5.0 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_transf_15 PF01793.11 EDO17399.1 - 7.9e-128 426.0 17.7 9.8e-128 425.7 12.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TcpQ PF10671.4 EDO17399.1 - 0.14 12.0 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q DUF1269 PF06897.7 EDO17399.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Ribosomal_L1 PF00687.16 EDO17400.1 - 5.1e-45 153.4 5.9 5.9e-45 153.2 4.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DEAD PF00270.24 EDO17401.1 - 2.9e-42 144.0 2.5 8e-42 142.5 0.3 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO17401.1 - 1.5e-27 95.2 0.1 4.7e-27 93.6 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO17401.1 - 3.9e-06 26.8 0.0 8.4e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EDO17401.1 - 0.0029 17.3 0.1 0.013 15.2 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EDO17401.1 - 0.024 14.2 0.0 0.079 12.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.1 EDO17401.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain SNF2_N PF00176.18 EDO17401.1 - 0.035 12.9 0.0 0.046 12.5 0.0 1.3 1 1 0 1 1 1 0 SNF2 family N-terminal domain CMS1 PF14617.1 EDO17401.1 - 0.086 11.9 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_S21e PF01249.13 EDO17402.1 - 1.2e-38 130.9 0.1 1.3e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Ras PF00071.17 EDO17403.1 - 7.8e-27 93.6 0.0 1.7e-26 92.5 0.0 1.5 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EDO17403.1 - 2.7e-11 43.9 0.0 2e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arch_ATPase PF01637.13 EDO17403.1 - 0.00037 20.2 1.5 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase MMR_HSR1 PF01926.18 EDO17403.1 - 0.0089 15.9 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EDO17403.1 - 0.013 14.7 0.0 0.029 13.6 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family PAP2 PF01569.16 EDO17404.1 - 9.4e-16 57.6 3.4 9.4e-16 57.6 2.4 1.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EDO17404.1 - 0.059 12.8 2.0 0.099 12.1 0.2 2.0 2 0 0 2 2 2 0 PAP2 superfamily BRCA-2_OB1 PF09103.5 EDO17405.1 - 0.0016 18.0 0.1 0.0064 16.1 0.0 2.0 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 NAD_Gly3P_dh_N PF01210.18 EDO17406.1 - 1.6e-52 177.4 0.0 2.5e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EDO17406.1 - 7.1e-47 158.8 0.1 1.2e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EDO17406.1 - 0.012 16.0 0.1 0.3 11.5 0.0 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EDO17406.1 - 0.027 14.7 0.0 0.085 13.1 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Arginosuc_synth PF00764.14 EDO17407.1 - 1e-161 538.3 0.0 1.2e-161 538.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EDO17407.1 - 2.4e-05 23.9 0.0 3.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EDO17407.1 - 4.2e-05 22.9 0.0 8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EDO17407.1 - 0.00044 18.9 0.0 0.00068 18.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase zf-C2H2_4 PF13894.1 EDO17408.1 - 6.6e-06 26.0 2.3 0.08 13.3 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO17408.1 - 0.014 15.7 13.8 0.05 13.9 0.2 3.4 3 1 0 3 3 3 0 Zinc finger, C2H2 type Oxysterol_BP PF01237.13 EDO17409.1 - 4.5e-128 426.6 0.2 7.8e-128 425.9 0.1 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.1 EDO17409.1 - 1.7e-11 43.9 0.3 0.00028 21.0 0.1 3.4 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO17409.1 - 3.6e-11 43.2 0.0 0.00016 21.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDO17409.1 - 4.5e-11 41.9 0.0 0.0003 20.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EDO17409.1 - 2.7e-10 40.4 0.1 0.00036 20.9 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO17409.1 - 2.5e-09 36.4 0.0 0.00097 19.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.1 EDO17409.1 - 1.4e-07 31.4 0.1 3.4e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EDO17409.1 - 2.6e-06 27.5 0.0 7.2e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EDO17409.1 - 9.6e-06 25.8 1.0 6.3e-05 23.1 0.7 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase PF00069.20 EDO17410.1 - 1.2e-72 244.1 0.1 2.3e-72 243.2 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17410.1 - 2.3e-54 184.2 0.0 4.1e-54 183.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17410.1 - 2.6e-05 23.3 0.1 0.0046 15.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.20 EDO17411.1 - 5.1e-56 189.7 0.1 6.6e-56 189.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17411.1 - 5.5e-33 114.1 0.0 2.2e-32 112.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase SAICAR_synt PF01259.13 EDO17412.1 - 3.5e-98 327.6 0.2 4.3e-98 327.3 0.1 1.1 1 0 0 1 1 1 1 SAICAR synthetase UPF0086 PF01868.11 EDO17412.1 - 0.0061 16.1 0.0 0.27 10.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function UPF0086 EMP24_GP25L PF01105.19 EDO17413.1 - 1.8e-27 96.2 4.4 1.8e-27 96.2 3.0 1.9 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD ATP-synt_8 PF00895.15 EDO17413.1 - 4.8 7.4 6.5 7.3 6.8 0.5 2.5 2 0 0 2 2 2 0 ATP synthase protein 8 RNA_pol_I_TF PF04090.7 EDO17415.1 - 1.6e-69 233.1 5.7 3.2e-69 232.1 3.9 1.5 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor Glucosaminidase PF01832.15 EDO17415.1 - 0.0056 16.8 1.3 0.016 15.3 0.9 1.7 1 0 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Nucleoplasmin PF03066.10 EDO17415.1 - 0.38 10.2 6.7 0.7 9.4 4.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin Aspzincin_M35 PF14521.1 EDO17415.1 - 2 8.9 7.8 8.5 6.8 2.2 3.2 3 1 0 3 3 3 0 Lysine-specific metallo-endopeptidase CENP-B_dimeris PF09026.5 EDO17415.1 - 7.7 6.8 9.7 18 5.6 6.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PLA2_B PF01735.13 EDO17416.1 - 8.1e-225 746.6 5.2 1e-224 746.2 3.6 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain TAF4 PF05236.9 EDO17417.1 - 4.3e-70 236.0 2.6 4.3e-70 236.0 1.8 2.2 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family DUF4611 PF15387.1 EDO17417.1 - 3.1 8.0 11.1 0.53 10.4 4.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RTC PF01137.16 EDO17418.1 - 3.2e-60 202.7 0.0 3.7e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EDO17418.1 - 7.1e-32 109.5 0.0 1.2e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.19 EDO17419.1 - 1.1e-20 73.4 1.9 2.2e-20 72.5 0.4 2.2 2 0 0 2 2 2 1 PX domain Polyketide_cyc PF03364.15 EDO17420.1 - 9.4e-18 64.4 0.0 1.2e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF2076 PF09849.4 EDO17421.1 - 1.1e-07 32.2 15.0 1.4e-07 31.8 10.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EDO17421.1 - 4.1e-05 23.3 4.4 6.6e-05 22.7 3.0 1.4 1 0 0 1 1 1 1 CHCH domain Med2 PF11214.3 EDO17421.1 - 0.25 11.4 1.6 0.35 10.9 1.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 2 TFIIA PF03153.8 EDO17421.1 - 2.1 8.1 9.2 2.4 7.9 6.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Topoisom_I_N PF02919.10 EDO17423.1 - 2.6e-98 327.6 0.5 2.6e-98 327.6 0.3 3.3 3 1 2 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EDO17423.1 - 2.7e-86 288.4 1.5 2.7e-86 288.4 1.1 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EDO17423.1 - 6.2e-33 112.2 0.6 2.1e-32 110.5 0.4 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain Pkinase PF00069.20 EDO17424.1 - 3.3e-74 249.3 0.0 5.5e-74 248.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17424.1 - 9.6e-41 139.5 0.0 1.5e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EDO17424.1 - 3.8e-34 116.4 0.1 1.6e-17 63.2 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EDO17424.1 - 4e-09 35.8 0.0 1.3e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like SH3_3 PF08239.6 EDO17424.1 - 0.00046 20.3 0.1 0.00089 19.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Kdo PF06293.9 EDO17424.1 - 0.0066 15.5 0.0 0.016 14.3 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_L_2 PF13656.1 EDO17425.1 - 3.6e-25 87.1 0.1 4.5e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EDO17425.1 - 2.8e-12 45.5 0.0 4e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Thymidylate_kin PF02223.12 EDO17425.1 - 0.053 12.8 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Thymidylate kinase PAH PF02671.16 EDO17426.1 - 9.9e-49 162.7 7.2 9.3e-19 66.7 0.3 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EDO17426.1 - 6.5e-44 147.8 0.3 2.8e-43 145.7 0.2 2.2 1 0 0 1 1 1 1 Sin3 family co-repressor zf-DHHC PF01529.15 EDO17427.1 - 2.8e-33 114.7 14.3 2.8e-33 114.7 9.9 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF367 PF04034.8 EDO17428.1 - 2.6e-54 182.2 0.0 4.3e-54 181.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EDO17428.1 - 5.4e-15 54.6 0.2 1.2e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI RHS_repeat PF05593.9 EDO17428.1 - 0.0075 16.4 0.1 0.19 11.9 0.0 2.4 2 0 0 2 2 2 1 RHS Repeat LcrG PF07216.7 EDO17428.1 - 0.041 13.9 0.2 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 LcrG protein DUF1090 PF06476.7 EDO17428.1 - 2.3 7.8 10.3 1.2 8.7 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) VPS9 PF02204.13 EDO17429.1 - 2.2e-12 46.9 0.4 8.6e-12 45.0 0.3 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EDO17429.1 - 0.0045 17.2 0.3 0.75 10.1 0.0 3.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EDO17429.1 - 0.041 14.1 0.0 3.6 7.9 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) TPR_11 PF13414.1 EDO17430.1 - 6e-26 89.8 10.5 1.6e-17 62.9 3.1 3.3 1 1 2 3 3 3 2 TPR repeat TPR_1 PF00515.23 EDO17430.1 - 1e-17 62.9 8.6 6.6e-08 31.8 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDO17430.1 - 3.7e-16 57.6 9.1 0.00011 21.8 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDO17430.1 - 4.8e-08 33.4 4.1 0.0001 22.8 0.7 2.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDO17430.1 - 1.7e-07 30.8 6.6 0.006 16.7 0.2 3.5 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO17430.1 - 1.1e-06 28.4 6.8 5.6e-06 26.2 0.6 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO17430.1 - 2.6e-06 27.5 0.4 0.29 11.9 0.0 3.7 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EDO17430.1 - 3.1e-06 26.5 9.1 0.0028 17.3 0.3 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDO17430.1 - 6.9e-05 23.1 5.3 0.021 15.1 0.4 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDO17430.1 - 0.00017 21.0 5.5 0.7 9.8 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat BTAD PF03704.12 EDO17430.1 - 0.0027 18.0 0.1 0.0027 18.0 0.1 2.0 2 1 0 2 2 2 1 Bacterial transcriptional activator domain HRDC PF00570.18 EDO17430.1 - 0.0078 15.9 0.2 0.11 12.2 0.1 2.3 2 0 0 2 2 2 1 HRDC domain TPR_10 PF13374.1 EDO17430.1 - 0.012 15.5 0.4 10 6.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EDO17430.1 - 0.13 12.4 4.9 0.065 13.3 1.7 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDO17430.1 - 0.14 12.6 12.5 0.34 11.4 0.1 4.2 4 1 0 4 4 3 0 Tetratricopeptide repeat PSD4 PF07631.6 EDO17430.1 - 0.81 10.0 4.6 0.62 10.4 1.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1592) Alg6_Alg8 PF03155.10 EDO17431.1 - 6.8e-160 532.9 30.5 8.2e-160 532.6 21.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ras PF00071.17 EDO17432.1 - 3.5e-57 192.2 0.5 4.2e-57 192.0 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO17432.1 - 1.9e-19 70.3 0.1 3.4e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO17432.1 - 1.7e-15 56.6 0.1 2e-15 56.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDO17432.1 - 3e-09 36.3 0.2 3.4e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO17432.1 - 2.8e-08 33.4 0.3 1e-06 28.3 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EDO17432.1 - 2.1e-06 27.0 0.2 2.9e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDO17432.1 - 6.9e-06 26.0 0.0 1.5e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EDO17432.1 - 1.9e-05 24.8 0.0 7.6e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO17432.1 - 4.7e-05 23.4 0.2 0.0041 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 EDO17432.1 - 6.1e-05 22.6 0.7 0.0024 17.4 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EDO17432.1 - 0.006 16.1 0.1 0.017 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EDO17432.1 - 0.0077 15.9 0.7 0.032 13.9 0.5 2.0 1 1 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 EDO17432.1 - 0.0089 15.2 0.1 0.022 13.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EDO17432.1 - 0.012 15.2 0.1 0.039 13.6 0.0 1.8 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EDO17432.1 - 0.015 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 EDO17432.1 - 0.019 14.6 0.1 0.062 13.0 0.0 1.8 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EDO17432.1 - 0.022 14.1 0.1 0.096 12.1 0.0 1.9 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EDO17432.1 - 0.023 14.1 0.4 0.14 11.6 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EDO17432.1 - 0.044 12.8 0.1 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_10 PF12846.2 EDO17432.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 EDO17432.1 - 0.1 11.4 0.1 0.24 10.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EDO17432.1 - 0.12 12.3 0.1 0.28 11.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain DNA_pol_A_exo1 PF01612.15 EDO17433.1 - 2.5e-48 163.8 0.7 6.5e-48 162.5 0.5 1.8 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EDO17433.1 - 4.1e-27 94.3 1.9 4.1e-27 94.3 1.3 2.9 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.18 EDO17433.1 - 2.5e-12 46.3 0.0 6.6e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Cyclin PF08613.6 EDO17434.1 - 2.1e-34 119.0 1.0 2.1e-34 119.0 0.7 1.9 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EDO17434.1 - 8.3e-05 22.1 0.1 0.00035 20.1 0.1 2.0 2 1 0 2 2 2 1 Cyclin, N-terminal domain Rabaptin PF03528.10 EDO17435.1 - 0.19 11.6 3.4 0.48 10.3 2.6 1.4 2 0 0 2 2 2 0 Rabaptin UBN2 PF14223.1 EDO17437.1 - 0.0047 16.7 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type RVT_2 PF07727.9 EDO17438.1 - 1.4e-35 122.4 0.1 2.6e-35 121.5 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO17438.1 - 1e-21 77.2 0.2 4.5e-20 71.9 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EDO17438.1 - 8.7e-05 22.0 0.1 0.00024 20.7 0.0 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 EDO17438.1 - 0.019 14.4 0.0 0.06 12.8 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain Cpn60_TCP1 PF00118.19 EDO17439.1 - 4.9e-117 391.5 7.0 5.7e-117 391.3 4.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DAGK_cat PF00781.19 EDO17440.1 - 5.3e-23 80.8 0.0 8.5e-23 80.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain FimP PF09766.4 EDO17440.1 - 0.0019 17.3 4.2 0.0028 16.7 2.9 1.2 1 0 0 1 1 1 1 Fms-interacting protein Menin PF05053.8 EDO17440.1 - 0.1 10.7 9.4 0.16 10.1 6.5 1.2 1 0 0 1 1 1 0 Menin CobT PF06213.7 EDO17440.1 - 1.5 7.8 5.2 2.4 7.2 3.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ndc1_Nup PF09531.5 EDO17440.1 - 9.3 4.5 7.8 12 4.1 5.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup tRNA-synt_1c PF00749.16 EDO17441.1 - 1.5e-109 365.4 0.0 2.6e-109 364.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 EDO17441.1 - 1.1e-57 194.1 0.7 2e-57 193.2 0.5 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 EDO17441.1 - 1.1e-35 122.8 0.1 3.1e-34 118.1 0.0 2.4 1 1 1 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 EDO17441.1 - 1.4e-25 89.8 4.9 3.5e-25 88.5 3.4 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Red1 PF07964.6 EDO17442.1 - 1e-272 906.5 64.3 1.2e-272 906.3 44.6 1.0 1 0 0 1 1 1 1 Rec10 / Red1 DUF2422 PF10337.4 EDO17442.1 - 0.36 9.5 4.1 0.62 8.7 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Ribosomal_S28e PF01200.13 EDO17443.1 - 1.4e-33 114.4 3.4 1.5e-33 114.3 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e PIN_4 PF13638.1 EDO17444.1 - 5.8e-33 113.8 0.0 1.1e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 PIN domain DUF61 PF01886.11 EDO17444.1 - 0.08 12.7 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF61 RHD3 PF05879.7 EDO17445.1 - 4.5e-236 785.3 24.2 5.7e-236 785.0 16.8 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 EDO17445.1 - 0.00014 21.6 0.9 0.00048 19.9 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EDO17445.1 - 0.0023 17.8 0.0 0.0078 16.1 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EDO17445.1 - 0.01 16.3 2.6 0.01 16.3 0.0 2.4 3 0 0 3 3 3 1 Miro-like protein DUF410 PF04190.8 EDO17446.1 - 2e-78 263.5 2.6 2.4e-78 263.2 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) NUDIX PF00293.23 EDO17447.1 - 8.8e-16 57.7 0.1 1.2e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain GalP_UDP_transf PF01087.17 EDO17448.1 - 2e-67 226.8 0.4 8.6e-67 224.7 0.1 1.9 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EDO17448.1 - 3.5e-64 215.3 0.4 9.3e-64 213.9 0.1 1.8 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalKase_gal_bdg PF10509.4 EDO17449.1 - 3e-22 77.6 0.0 6e-22 76.6 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EDO17449.1 - 1.1e-14 54.1 0.2 2.8e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDO17449.1 - 1.4e-11 44.4 0.0 2.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4 PF04545.11 EDO17449.1 - 0.06 12.6 0.0 0.16 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.1 EDO17449.1 - 0.068 12.8 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_11 PF08279.7 EDO17449.1 - 0.11 12.2 0.0 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 HTH domain Sigma70_ECF PF07638.6 EDO17449.1 - 0.13 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 ECF sigma factor ABC2_membrane PF01061.19 EDO17450.1 - 6.4e-64 214.9 64.9 1.2e-36 125.9 14.3 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EDO17450.1 - 3.8e-38 130.8 0.3 1.4e-17 64.2 0.0 3.1 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EDO17450.1 - 2.3e-33 113.8 8.1 2.6e-28 97.6 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter DUF258 PF03193.11 EDO17450.1 - 4.7e-07 29.1 0.9 0.00015 21.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EDO17450.1 - 2.3e-05 23.9 2.2 0.00013 21.4 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EDO17450.1 - 3.2e-05 23.3 0.4 0.033 13.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EDO17450.1 - 0.00014 22.0 0.5 0.0096 16.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EDO17450.1 - 0.00014 21.3 0.4 0.01 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EDO17450.1 - 0.00042 20.3 0.4 0.18 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EDO17450.1 - 0.00069 18.9 0.0 0.47 9.6 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC_trans_N PF14510.1 EDO17450.1 - 0.00075 19.5 0.0 0.0041 17.1 0.0 2.3 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal Miro PF08477.8 EDO17450.1 - 0.0009 19.7 0.1 1.3 9.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EDO17450.1 - 0.0015 18.4 0.4 0.4 10.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 EDO17450.1 - 0.0036 16.2 0.3 0.2 10.4 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 EDO17450.1 - 0.0039 16.6 0.7 0.79 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EDO17450.1 - 0.0057 16.9 0.2 0.45 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO17450.1 - 0.0086 15.8 0.5 2.4 7.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EDO17450.1 - 0.012 15.4 0.6 0.19 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EDO17450.1 - 0.014 15.0 1.2 0.29 10.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain Septin PF00735.13 EDO17450.1 - 0.014 14.3 0.1 0.066 12.2 0.0 1.9 2 0 0 2 2 2 0 Septin UPF0079 PF02367.12 EDO17450.1 - 0.021 14.4 0.7 0.26 10.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EDO17450.1 - 0.027 13.9 0.8 6 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EDO17450.1 - 0.042 13.3 0.4 0.26 10.7 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EDO17450.1 - 0.045 13.4 0.1 4.8 6.8 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 EDO17450.1 - 0.047 13.3 2.2 14 5.3 0.1 3.2 3 0 0 3 3 3 0 NTPase AAA_17 PF13207.1 EDO17450.1 - 0.06 14.1 0.2 0.53 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EDO17450.1 - 0.061 12.8 0.9 2.7 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EDO17450.1 - 0.18 11.7 1.0 0.37 10.7 0.1 1.9 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 EDO17450.1 - 0.23 10.5 0.4 3.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 EDO17450.1 - 0.25 10.9 1.1 4.1 6.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 EDO17450.1 - 0.48 9.4 55.0 0.92 8.4 14.4 3.7 2 2 0 2 2 2 0 ABC-2 family transporter protein Macro PF01661.16 EDO17451.1 - 4.7e-26 91.0 0.0 1.1e-25 89.8 0.0 1.5 1 1 0 1 1 1 1 Macro domain Chitin_synth_2 PF03142.10 EDO17452.1 - 4.3e-287 952.6 0.1 4.3e-287 952.6 0.1 1.6 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EDO17452.1 - 9.7e-16 58.0 6.2 4.7e-15 55.8 4.3 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDO17452.1 - 3.3e-14 53.2 0.0 1.6e-12 47.7 0.0 2.8 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EDO17452.1 - 2.4e-08 33.6 0.1 4.6e-06 26.3 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EDO17452.1 - 0.00056 19.2 0.0 0.0017 17.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDO17452.1 - 0.00065 19.4 0.0 0.0072 16.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 fn3_3 PF14686.1 EDO17452.1 - 0.11 12.6 1.3 0.46 10.6 0.1 2.5 3 0 0 3 3 3 0 Polysaccharide lyase family 4, domain II SCO1-SenC PF02630.9 EDO17453.1 - 7.5e-64 214.5 0.0 1.1e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 EDO17453.1 - 0.00052 20.0 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Pkinase PF00069.20 EDO17455.1 - 6.2e-64 215.6 0.1 1.6e-63 214.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17455.1 - 1.9e-32 112.3 0.0 3.4e-31 108.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EDO17455.1 - 0.00094 19.6 0.0 0.0036 17.7 0.0 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDO17455.1 - 0.0025 16.8 0.0 0.013 14.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like CTP_transf_1 PF01148.15 EDO17456.1 - 2.2e-77 260.2 25.8 2.8e-77 259.8 17.9 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Methyltransf_31 PF13847.1 EDO17457.1 - 2.1e-14 53.4 0.0 3.3e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDO17457.1 - 1.9e-11 43.6 0.0 3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EDO17457.1 - 4.1e-10 39.6 0.0 7.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO17457.1 - 7.5e-10 39.3 0.0 2.5e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO17457.1 - 7.8e-08 32.7 0.0 1.7e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EDO17457.1 - 1.6e-07 30.6 0.1 2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.1 EDO17457.1 - 2.5e-07 30.5 0.0 3.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EDO17457.1 - 8.4e-07 27.9 0.1 1.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EDO17457.1 - 3e-06 27.5 0.0 8.9e-06 26.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 EDO17457.1 - 3.3e-06 26.6 0.0 5.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EDO17457.1 - 1.2e-05 24.5 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EDO17457.1 - 5.9e-05 23.4 0.0 0.00014 22.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EDO17457.1 - 0.00037 20.5 0.0 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EDO17457.1 - 0.0011 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 EDO17457.1 - 0.0086 15.1 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 EDO17457.1 - 0.0089 15.7 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EDO17457.1 - 0.009 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EDO17457.1 - 0.011 14.9 0.2 0.022 13.8 0.1 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DOT1 PF08123.8 EDO17457.1 - 0.082 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 UPF0020 PF01170.13 EDO17457.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DASH_Dad1 PF08649.5 EDO17458.1 - 1.4e-28 98.3 0.2 1.7e-28 98.0 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 IPK PF03770.11 EDO17459.1 - 3.3e-47 160.6 1.2 4.6e-47 160.2 0.0 1.9 2 0 0 2 2 2 1 Inositol polyphosphate kinase Fig1 PF12351.3 EDO17460.1 - 9.2e-58 195.1 5.4 9.2e-58 195.1 3.8 1.9 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 DUF749 PF05370.6 EDO17460.1 - 0.08 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF749) 4HB_MCP_1 PF12729.2 EDO17460.1 - 0.67 9.2 4.9 0.92 8.8 0.0 3.0 3 0 0 3 3 3 0 Four helix bundle sensory module for signal transduction ASFV_J13L PF05568.6 EDO17460.1 - 0.73 9.3 4.0 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein Acyltransferase PF01553.16 EDO17461.1 - 8.3e-29 99.6 0.0 1.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase tRNA-synt_2b PF00587.20 EDO17463.1 - 5.6e-36 123.7 0.8 1.2e-35 122.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EDO17463.1 - 6e-23 80.9 10.7 6e-23 80.9 7.4 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF1049 PF06305.6 EDO17463.1 - 0.062 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Amidase_6 PF12671.2 EDO17463.1 - 0.4 10.7 3.4 4.6 7.2 0.5 2.3 2 0 0 2 2 2 0 Putative amidase domain DJ-1_PfpI PF01965.19 EDO17465.1 - 7.7e-24 83.8 0.0 1.6e-23 82.8 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EDO17465.1 - 7.2e-05 22.2 0.1 0.0002 20.8 0.1 1.8 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Homeobox PF00046.24 EDO17466.1 - 2.9e-14 52.4 0.9 4.7e-14 51.7 0.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EDO17466.1 - 6e-06 25.8 0.4 1.4e-05 24.7 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 EDO17466.1 - 0.0028 16.6 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Plasmodium_HRP PF05403.6 EDO17467.1 - 3.6e-12 46.3 0.0 0.83 9.1 0.0 7.3 7 0 0 7 7 7 5 Plasmodium histidine-rich protein (HRPII/III) PA14_2 PF10528.4 EDO17467.1 - 1.2e-10 41.3 1.8 6.6e-10 38.9 1.2 2.4 1 0 0 1 1 1 1 GLEYA domain ASXH PF13919.1 EDO17468.1 - 1.7 8.4 15.1 34 4.2 0.2 5.1 1 1 6 7 7 7 0 Asx homology domain Flocculin PF00624.13 EDO17469.1 - 1.7e-12 46.9 22.0 1.7e-12 46.9 15.2 11.2 11 2 1 12 12 12 1 Flocculin repeat Rdx PF10262.4 EDO17470.1 - 2e-26 91.7 0.0 2.6e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Rdx family USP8_dimer PF08969.6 EDO17471.1 - 6.4e-06 26.1 1.8 9.5e-06 25.5 0.8 1.7 1 1 0 1 1 1 1 USP8 dimerisation domain DUF1007 PF06226.8 EDO17471.1 - 0.073 12.8 0.3 0.09 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) GRAM PF02893.15 EDO17472.1 - 2.7e-18 65.2 0.1 6.5e-18 64.0 0.0 1.7 2 0 0 2 2 2 1 GRAM domain Lzipper-MIP1 PF14389.1 EDO17472.1 - 0.029 14.4 1.1 0.073 13.1 0.8 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Med14 PF08638.6 EDO17473.1 - 1.2e-66 223.7 1.5 1.2e-66 223.7 1.0 2.0 2 0 0 2 2 2 1 Mediator complex subunit MED14 ADH_N PF08240.7 EDO17474.1 - 6.1e-28 96.7 5.0 3.7e-27 94.2 0.1 3.0 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO17474.1 - 8.3e-26 90.0 0.0 1.5e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDO17474.1 - 0.018 15.9 0.0 0.034 15.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EDO17474.1 - 0.028 13.8 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cu-oxidase_2 PF07731.9 EDO17475.1 - 1.8e-41 140.9 7.6 4.2e-39 133.2 0.7 2.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EDO17475.1 - 6.4e-36 122.6 3.8 3.6e-32 110.5 0.1 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EDO17475.1 - 2.2e-35 121.8 0.5 1.3e-32 112.8 0.0 3.6 4 0 0 4 4 4 1 Multicopper oxidase Cupredoxin_1 PF13473.1 EDO17475.1 - 0.0011 18.7 0.0 1.9 8.4 0.0 3.7 3 1 0 4 4 4 1 Cupredoxin-like domain rRNA_processing PF08524.6 EDO17476.1 - 2.7e-40 137.5 24.3 3.1e-40 137.3 16.8 1.0 1 0 0 1 1 1 1 rRNA processing DUF3835 PF12927.2 EDO17476.1 - 0.81 10.6 9.2 0.097 13.6 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) PPR_2 PF13041.1 EDO17477.1 - 1.9e-18 66.1 6.7 0.00056 19.8 0.0 8.4 6 1 4 10 10 10 4 PPR repeat family PPR_3 PF13812.1 EDO17477.1 - 2.2e-12 46.2 0.7 0.49 10.8 0.0 9.1 10 0 0 10 10 10 4 Pentatricopeptide repeat domain PPR PF01535.15 EDO17477.1 - 4.2e-10 38.9 13.0 2.8 8.1 0.0 9.8 11 0 0 11 11 11 4 PPR repeat PPR_1 PF12854.2 EDO17477.1 - 0.19 11.2 1.4 8.1 6.0 0.0 3.7 4 0 0 4 4 4 0 PPR repeat Actin PF00022.14 EDO17478.1 - 2.7e-160 533.1 0.0 3.1e-160 532.9 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EDO17478.1 - 0.044 14.1 0.0 0.18 12.1 0.0 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3115 PF11312.3 EDO17480.1 - 2.7e-105 351.7 1.2 3.1e-105 351.5 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) LuxS PF02664.10 EDO17480.1 - 0.06 12.8 0.1 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) GidB PF02527.10 EDO17480.1 - 0.084 11.9 0.1 8.5 5.4 0.0 2.6 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G DUF726 PF05277.7 EDO17481.1 - 8.5e-93 310.9 2.5 8.5e-93 310.9 1.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF726) LpxC PF03331.8 EDO17481.1 - 0.029 13.3 0.7 0.048 12.5 0.5 1.3 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase DUF106 PF01956.11 EDO17481.1 - 0.42 10.1 2.7 1.7 8.1 0.1 2.6 2 1 0 2 2 2 0 Integral membrane protein DUF106 bZIP_2 PF07716.10 EDO17482.1 - 2.2e-06 27.3 9.4 4.8e-06 26.3 6.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EDO17482.1 - 8.2e-05 22.4 11.9 8.2e-05 22.4 8.3 1.6 2 0 0 2 2 2 1 bZIP transcription factor DUF2360 PF10152.4 EDO17482.1 - 0.092 13.0 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) SHMT PF00464.14 EDO17483.1 - 8.5e-208 689.5 0.0 9.8e-208 689.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EDO17483.1 - 3.6e-06 26.1 0.0 6.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDO17483.1 - 4.1e-05 22.4 0.0 6.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EDO17483.1 - 0.0053 15.9 0.0 0.0085 15.2 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase FA_hydroxylase PF04116.8 EDO17484.1 - 2.2e-11 44.1 20.1 2.2e-11 44.1 14.0 2.4 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily STE2 PF02116.10 EDO17485.1 - 6e-105 350.3 18.5 7.1e-105 350.1 12.8 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR PGAP1 PF07819.8 EDO17486.1 - 3.6e-88 294.9 0.0 6.2e-88 294.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EDO17486.1 - 0.0013 18.4 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO17486.1 - 0.0022 17.8 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EDO17486.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 EDO17486.1 - 0.041 13.2 0.0 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 EDO17486.1 - 0.3 10.6 0.0 0.57 9.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3835 PF12927.2 EDO17487.1 - 2.2e-19 70.1 0.4 2.2e-19 70.1 0.3 8.5 7 3 2 9 9 9 2 Domain of unknown function (DUF3835) Prefoldin PF02996.12 EDO17487.1 - 3.1e-09 36.5 0.0 3.1e-09 36.5 0.0 3.4 3 0 0 3 3 3 1 Prefoldin subunit GATA PF00320.22 EDO17490.1 - 7.4e-18 63.6 1.9 1.5e-17 62.6 1.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EDO17490.1 - 2.4e-08 33.4 2.7 2.4e-08 33.4 1.9 2.6 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) DUF2781 PF10914.3 EDO17491.1 - 2.6e-37 127.9 5.6 3.5e-37 127.4 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) HSP9_HSP12 PF04119.7 EDO17492.1 - 3.3e-05 23.8 4.5 0.00013 21.9 0.7 2.4 1 1 1 2 2 2 1 Heat shock protein 9/12 DUF1664 PF07889.7 EDO17492.1 - 0.014 15.2 0.4 0.02 14.7 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Dzip-like_N PF13815.1 EDO17492.1 - 0.08 12.7 0.5 0.11 12.3 0.3 1.3 1 1 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Inhibitor_I34 PF10466.4 EDO17492.1 - 0.089 12.8 0.1 0.089 12.8 0.0 2.0 2 1 0 2 2 2 0 Saccharopepsin inhibitor I34 DUF3552 PF12072.3 EDO17492.1 - 0.11 11.6 1.6 0.13 11.4 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF16 PF01519.11 EDO17492.1 - 0.12 12.5 1.4 0.14 12.3 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Rota_VP2 PF05087.7 EDO17492.1 - 1 7.1 3.2 1 7.1 2.2 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein WD40 PF00400.27 EDO17494.1 - 6.4e-48 158.9 14.9 4.6e-10 38.9 0.2 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EDO17494.1 - 2.9e-10 39.7 0.9 6.9e-10 38.5 0.6 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO17494.1 - 2.9e-09 36.3 1.4 6.5e-09 35.2 1.0 1.6 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 EDO17494.1 - 4.5e-05 23.3 0.7 0.00016 21.5 0.5 2.0 1 0 0 1 1 1 1 PRANC domain Nucleoporin_N PF08801.6 EDO17494.1 - 0.0017 17.2 4.7 0.77 8.4 0.0 3.5 2 1 2 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 EDO17494.1 - 0.0072 14.5 3.1 1.8 6.6 0.1 4.0 3 2 0 3 3 3 1 Nucleoporin Nup120/160 JmjC PF02373.17 EDO17494.1 - 0.048 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 JmjC domain, hydroxylase DUF3437 PF11919.3 EDO17495.1 - 3.2e-28 97.2 0.0 1.2e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) DUF424 PF04242.8 EDO17495.1 - 0.029 14.4 2.6 0.098 12.7 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF424) VTC PF09359.5 EDO17496.1 - 3.5e-96 321.5 0.7 3.5e-96 321.5 0.5 2.3 3 0 0 3 3 3 1 VTC domain SPX PF03105.14 EDO17496.1 - 1.2e-21 77.6 28.7 2.7e-14 53.6 5.0 4.0 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 EDO17496.1 - 1.1e-09 38.4 0.4 2.6e-09 37.1 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Peptidase_C48 PF02902.14 EDO17497.1 - 4.2e-35 121.3 0.4 6.9e-35 120.6 0.3 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MutS_V PF00488.16 EDO17498.1 - 1.9e-60 204.1 0.2 3.7e-60 203.2 0.2 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDO17498.1 - 4.1e-28 98.5 4.2 4.1e-28 98.5 2.9 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EDO17498.1 - 5.3e-07 29.7 0.4 3.4e-06 27.1 0.0 2.6 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EDO17498.1 - 3.7e-06 27.0 11.1 4.4e-06 26.7 0.5 3.5 3 0 0 3 3 3 2 MutS family domain IV DUF3441 PF11923.3 EDO17499.1 - 3.5e-34 116.7 0.5 3.5e-34 116.7 0.3 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EDO17499.1 - 4.1e-20 71.7 33.4 4.1e-20 71.7 23.1 3.3 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EDO17499.1 - 3.1e-10 39.7 0.0 9.7e-10 38.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Clat_adaptor_s PF01217.15 EDO17500.1 - 6.9e-16 58.2 0.2 1e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SplA PF11132.3 EDO17500.1 - 0.02 14.6 0.2 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator protein (SplA) Glyco_transf_25 PF01755.12 EDO17500.1 - 0.033 13.8 0.3 0.058 13.0 0.2 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Bromo_TP PF07524.8 EDO17501.1 - 9.5e-06 25.2 0.1 1.9e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated NUC173 PF08161.7 EDO17502.1 - 1.3e-76 256.3 0.1 1.3e-74 249.9 0.1 2.9 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.17 EDO17502.1 - 5.1e-06 26.1 4.3 1 9.6 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 EDO17502.1 - 0.00031 20.9 0.1 2.8 8.2 0.0 3.8 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EDO17502.1 - 0.025 15.0 0.6 98 3.6 0.0 4.9 4 1 1 5 5 5 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDO17502.1 - 0.09 13.1 3.2 2.5 8.5 0.0 4.3 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region Ribosomal_S16 PF00886.14 EDO17503.1 - 7.3e-26 89.6 0.0 9.4e-26 89.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 PDR_assoc PF08370.6 EDO17503.1 - 0.047 13.1 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Plant PDR ABC transporter associated UBACT PF02134.16 EDO17505.1 - 0.066 12.8 0.8 0.21 11.1 0.2 2.2 2 0 0 2 2 2 0 Repeat in ubiquitin-activating (UBA) protein DEAD PF00270.24 EDO17506.1 - 5.1e-38 130.2 0.6 1.2e-37 128.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO17506.1 - 1.6e-20 72.7 0.0 5.6e-20 70.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EDO17506.1 - 2.4e-15 55.7 0.1 6.6e-15 54.4 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EDO17506.1 - 0.00017 21.4 0.0 0.00017 21.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PseudoU_synth_1 PF01416.15 EDO17507.1 - 7.3e-30 103.4 0.0 1.4e-18 67.2 0.0 3.0 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF2201_N PF13203.1 EDO17507.1 - 0.19 10.8 0.8 0.39 9.8 0.5 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Hat1_N PF10394.4 EDO17508.1 - 5.2e-37 127.4 5.3 5.2e-37 127.4 3.7 2.0 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 EDO17508.1 - 0.00048 20.1 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO17508.1 - 0.0035 17.4 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NfI_DNAbd_pre-N PF10524.4 EDO17508.1 - 0.063 12.8 0.2 0.16 11.6 0.2 1.7 1 0 0 1 1 1 0 Nuclear factor I protein pre-N-terminus Phage_C PF12025.3 EDO17508.1 - 0.065 13.2 0.9 0.38 10.7 0.2 2.4 2 0 0 2 2 2 0 Phage protein C Acetyltransf_10 PF13673.1 EDO17508.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GlutR_dimer PF00745.15 EDO17509.1 - 0.041 13.8 4.1 0.052 13.5 1.7 2.0 1 1 1 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Nic96 PF04097.9 EDO17510.1 - 4e-05 21.9 0.1 6.2e-05 21.3 0.1 1.3 1 0 0 1 1 1 1 Nup93/Nic96 DUF276 PF03434.8 EDO17510.1 - 0.0015 17.5 0.7 0.0023 16.9 0.5 1.3 1 0 0 1 1 1 1 DUF276 DUF2863 PF11062.3 EDO17510.1 - 0.043 11.9 0.3 0.062 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) MazG-like PF12643.2 EDO17510.1 - 0.044 13.7 0.2 0.12 12.2 0.1 1.8 1 1 0 1 1 1 0 MazG-like family Osmo_CC PF08946.5 EDO17510.1 - 0.73 9.9 3.6 1.2 9.2 0.3 2.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Nic96 PF04097.9 EDO17511.1 - 1.3e-43 149.0 8.1 1.5e-43 148.9 5.6 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Alpha-E PF04168.7 EDO17511.1 - 0.0053 16.1 0.3 0.052 12.9 0.2 2.0 1 1 0 1 1 1 1 A predicted alpha-helical domain with a conserved ER motif. DUF2150 PF09920.4 EDO17511.1 - 0.087 12.4 1.5 0.25 10.9 1.0 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) PPI_Ypi1 PF07491.6 EDO17512.1 - 7.3e-06 25.5 16.5 7.3e-06 25.5 11.4 2.5 2 2 0 2 2 2 1 Protein phosphatase inhibitor CDC45 PF02724.9 EDO17512.1 - 1.9 6.3 11.6 1.9 6.4 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Cyto_heme_lyase PF01265.12 EDO17513.1 - 3.4e-46 157.9 0.0 3.9e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PPR_3 PF13812.1 EDO17514.1 - 0.00049 20.1 0.0 4.9 7.7 0.0 4.0 3 1 0 3 3 3 2 Pentatricopeptide repeat domain SRR PF07709.6 EDO17514.1 - 0.12 12.5 0.9 4.1 8.0 0.4 3.3 2 0 0 2 2 2 0 Seven Residue Repeat DUF382 PF04037.8 EDO17515.1 - 0.24 11.2 4.4 0.42 10.4 2.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF382) LMBR1 PF04791.11 EDO17515.1 - 9.4 4.6 8.6 0.37 9.3 2.2 1.5 2 0 0 2 2 2 0 LMBR1-like membrane protein DEAD PF00270.24 EDO17516.1 - 1.4e-34 119.0 0.2 3.3e-34 117.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO17516.1 - 5.2e-23 80.7 0.0 4.8e-22 77.6 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO17516.1 - 4.7e-05 23.3 0.1 0.00014 21.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pyr_redox_2 PF07992.9 EDO17517.1 - 2.8e-28 99.1 0.0 5.3e-19 68.8 0.0 3.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO17517.1 - 4.7e-09 36.5 0.0 4.7e-08 33.3 0.0 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO17517.1 - 4.4e-07 30.1 0.1 0.00012 22.1 0.1 3.5 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EDO17517.1 - 0.0068 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) DLH PF01738.13 EDO17518.1 - 1.4e-25 89.8 0.0 1.8e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EDO17518.1 - 3.2e-07 30.1 0.0 4.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDO17518.1 - 4.9e-05 22.6 0.2 0.0015 17.7 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family DUF2305 PF10230.4 EDO17518.1 - 0.0032 16.9 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 EDO17518.1 - 0.0055 15.6 0.0 0.0075 15.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EDO17518.1 - 0.037 12.8 0.0 0.047 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.6 EDO17518.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal adh_short PF00106.20 EDO17519.1 - 1.4e-05 25.0 0.3 6e-05 23.0 0.2 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EDO17519.1 - 0.0022 18.0 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EDO17519.1 - 0.0086 15.5 0.1 0.018 14.5 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EDO17519.1 - 0.014 15.1 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO17519.1 - 0.016 14.8 0.5 0.16 11.6 0.4 2.1 1 1 0 1 1 1 0 KR domain CRC_subunit PF08624.5 EDO17520.1 - 3.3e-49 166.3 0.0 1.2e-48 164.6 0.0 1.9 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Nop14 PF04147.7 EDO17520.1 - 0.79 7.5 15.5 1 7.1 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 EDO17520.1 - 8.2 4.3 8.0 12 3.8 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Hap4_Hap_bind PF10297.4 EDO17521.1 - 1.4e-09 37.4 5.7 2.7e-09 36.5 3.9 1.5 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 DUF4587 PF15248.1 EDO17521.1 - 0.18 12.4 2.1 0.38 11.3 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) Glyco_hydro_38 PF01074.17 EDO17522.1 - 8e-82 274.5 0.4 1.3e-81 273.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EDO17522.1 - 1.1e-68 232.1 1.9 1.5e-68 231.6 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EDO17522.1 - 3.9e-21 75.0 0.0 1.2e-20 73.5 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Prenyltrans PF00432.16 EDO17523.1 - 1.9e-28 97.6 0.1 2.1e-07 30.3 0.0 5.0 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDO17523.1 - 4.2e-16 59.3 0.0 0.00022 21.6 0.0 3.7 3 1 1 4 4 4 3 Prenyltransferase-like Pex14_N PF04695.8 EDO17524.1 - 3.8e-34 117.6 9.5 3.5e-33 114.5 1.7 3.5 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 EDO17524.1 - 0.00032 20.5 3.6 0.00073 19.3 2.5 1.6 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EDO17524.1 - 0.00095 18.9 1.4 0.0022 17.7 0.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) CR6_interact PF10147.4 EDO17524.1 - 0.0015 17.9 1.4 0.0027 17.0 1.0 1.6 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF2450 PF10475.4 EDO17524.1 - 0.0051 15.7 3.3 0.0079 15.1 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) ALIX_LYPXL_bnd PF13949.1 EDO17524.1 - 0.0087 15.0 10.2 0.016 14.1 7.1 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Reo_sigmaC PF04582.7 EDO17524.1 - 0.019 14.1 3.8 0.03 13.5 2.7 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4615 PF15393.1 EDO17524.1 - 0.029 14.6 6.2 1 9.5 0.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4615) Myosin_tail_1 PF01576.14 EDO17524.1 - 0.052 11.2 18.1 0.0085 13.8 9.2 1.8 2 0 0 2 2 2 0 Myosin tail MbeD_MobD PF04899.7 EDO17524.1 - 0.06 13.2 1.9 0.16 11.9 1.3 1.7 1 0 0 1 1 1 0 MbeD/MobD like FlgN PF05130.7 EDO17524.1 - 0.06 13.5 9.2 0.11 12.6 6.4 1.4 1 0 0 1 1 1 0 FlgN protein Nup88 PF10168.4 EDO17524.1 - 0.098 10.4 5.6 0.14 9.9 3.9 1.2 1 0 0 1 1 1 0 Nuclear pore component Atg14 PF10186.4 EDO17524.1 - 0.15 10.9 8.6 0.3 9.9 6.0 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 THOC7 PF05615.8 EDO17524.1 - 0.17 12.1 12.6 0.21 11.8 7.6 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 Poty_PP PF08440.5 EDO17524.1 - 0.18 10.8 6.7 0.4 9.7 4.6 1.5 1 0 0 1 1 1 0 Potyviridae polyprotein DUF948 PF06103.6 EDO17524.1 - 0.28 11.0 4.7 0.39 10.5 0.4 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 EDO17524.1 - 0.36 9.4 15.9 0.81 8.2 11.0 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EDO17524.1 - 0.41 10.2 11.8 0.35 10.4 7.4 1.5 1 1 0 1 1 1 0 IncA protein LXG PF04740.7 EDO17524.1 - 0.44 10.3 12.5 0.58 9.9 5.9 2.4 1 1 1 2 2 2 0 LXG domain of WXG superfamily NPV_P10 PF05531.7 EDO17524.1 - 1 9.6 6.7 2.2 8.6 1.0 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein L31 PF09784.4 EDO17524.1 - 1 9.4 3.4 3 7.9 1.2 2.6 1 1 1 2 2 2 0 Mitochondrial ribosomal protein L31 V-SNARE PF05008.10 EDO17524.1 - 1.7 8.8 10.4 3.7 7.7 5.4 2.9 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus UPF0184 PF03670.8 EDO17524.1 - 1.7 8.9 7.0 16 5.7 3.7 2.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Prefoldin_2 PF01920.15 EDO17524.1 - 1.7 8.4 16.8 1.5 8.5 4.7 3.4 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.6 EDO17524.1 - 2 8.3 9.9 0.34 10.8 0.4 3.9 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) EMP24_GP25L PF01105.19 EDO17524.1 - 2.5 7.7 9.9 0.84 9.3 3.5 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF3513 PF12026.3 EDO17524.1 - 2.5 7.5 12.0 0.029 13.9 2.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3513) DUF4164 PF13747.1 EDO17524.1 - 3.2 7.9 11.6 1.1 9.4 0.1 2.8 2 1 1 3 3 2 0 Domain of unknown function (DUF4164) Syntaxin PF00804.20 EDO17524.1 - 3.6 7.8 16.4 1.7e+02 2.4 11.5 2.8 1 1 0 1 1 1 0 Syntaxin V_ATPase_I PF01496.14 EDO17524.1 - 3.7 5.2 10.3 6 4.5 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4200 PF13863.1 EDO17524.1 - 4 7.4 16.0 5.5 6.9 10.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) APG6 PF04111.7 EDO17524.1 - 4.4 6.2 15.5 0.38 9.7 7.4 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 Sipho_Gp157 PF05565.6 EDO17524.1 - 4.5 6.8 13.6 4.3 6.9 5.1 2.9 2 1 1 3 3 3 0 Siphovirus Gp157 Syntaxin-6_N PF09177.6 EDO17524.1 - 4.6 7.6 17.3 1.8 9.0 1.8 3.7 3 1 2 5 5 3 0 Syntaxin 6, N-terminal AAA_13 PF13166.1 EDO17524.1 - 5.4 5.3 19.0 1.8 6.9 7.8 1.7 1 1 1 2 2 2 0 AAA domain CCDC-167 PF15188.1 EDO17524.1 - 6.6 6.7 14.3 0.98 9.4 1.1 3.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 Fib_alpha PF08702.5 EDO17524.1 - 8.3 6.5 10.1 35 4.4 6.8 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Med5 PF08689.5 EDO17525.1 - 0 1044.2 49.4 0 1044.0 34.2 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SNF2_N PF00176.18 EDO17526.1 - 5.2e-73 245.4 2.9 5.2e-73 245.4 2.0 3.3 3 0 0 3 3 3 1 SNF2 family N-terminal domain DBINO PF13892.1 EDO17526.1 - 3.4e-49 166.4 22.1 3.4e-49 166.4 15.3 5.8 5 1 0 6 6 6 1 DNA-binding domain Helicase_C PF00271.26 EDO17526.1 - 4.1e-13 49.0 0.0 1.5e-12 47.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RHH_4 PF13467.1 EDO17526.1 - 0.051 13.4 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix domain SH3_9 PF14604.1 EDO17527.1 - 1.4e-06 27.8 0.1 3.7e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDO17527.1 - 0.00058 19.2 0.1 0.00058 19.2 0.1 2.6 3 0 0 3 3 3 1 SH3 domain SH3_2 PF07653.12 EDO17527.1 - 0.0033 16.8 0.1 0.0071 15.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF1762 PF08574.5 EDO17528.1 - 8.6e-20 70.9 12.5 8.6e-20 70.9 8.7 3.8 2 1 1 4 4 4 1 Protein of unknown function (DUF1762) adh_short PF00106.20 EDO17529.1 - 1.4e-27 96.6 0.0 2.5e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO17529.1 - 1.4e-10 41.1 0.0 5e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EDO17529.1 - 1.1e-09 38.4 0.0 1.7e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EDO17529.1 - 0.02 14.3 0.0 0.049 13.0 0.0 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EDO17529.1 - 0.036 14.0 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding RNase_PH PF01138.16 EDO17530.1 - 3.4e-18 66.2 0.4 4.8e-18 65.7 0.3 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 EMP24_GP25L PF01105.19 EDO17531.1 - 1e-08 35.0 1.6 1.5e-08 34.6 1.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD BLOC1_2 PF10046.4 EDO17532.1 - 0.0013 18.8 1.6 1.3 9.2 0.0 2.4 2 1 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 RhoGAP PF00620.22 EDO17532.1 - 0.073 12.6 0.1 0.22 11.1 0.0 1.8 2 0 0 2 2 2 0 RhoGAP domain DUF4635 PF15466.1 EDO17532.1 - 0.075 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4635) APG6 PF04111.7 EDO17532.1 - 0.11 11.5 2.7 0.14 11.1 1.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF676 PF05057.9 EDO17533.1 - 1.9e-58 197.3 0.1 3.4e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 EDO17533.1 - 0.0022 17.0 0.2 0.0063 15.5 0.0 1.8 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 EDO17533.1 - 0.0027 17.3 0.0 0.0056 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EDO17533.1 - 0.0046 16.5 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein RF-1 PF00472.15 EDO17534.1 - 2.3e-39 133.7 3.4 4.2e-39 132.8 2.4 1.4 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EDO17534.1 - 1.9e-30 104.9 0.4 7e-30 103.1 0.0 2.1 2 0 0 2 2 2 1 PCRF domain DUF3508 PF12018.3 EDO17534.1 - 0.041 12.8 0.2 0.082 11.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) Pkinase PF00069.20 EDO17535.1 - 1.7e-72 243.7 0.0 2e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17535.1 - 3.3e-30 105.0 0.0 4.9e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17535.1 - 0.0042 16.0 0.0 0.0084 15.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EDO17535.1 - 0.012 15.3 0.1 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Dexa_ind PF15198.1 EDO17535.1 - 0.04 13.8 0.1 0.098 12.5 0.1 1.6 1 0 0 1 1 1 0 Dexamethasone-induced TPR_11 PF13414.1 EDO17536.1 - 7.2e-09 35.1 0.6 5.6e-05 22.7 0.0 3.2 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EDO17536.1 - 7.1e-08 31.7 2.6 0.0027 17.5 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO17536.1 - 3e-07 30.2 0.1 1.6e-05 24.7 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO17536.1 - 0.00033 21.2 0.0 0.16 12.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO17536.1 - 0.0012 18.4 8.2 0.037 13.8 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO17536.1 - 0.0028 18.1 0.0 0.2 12.3 0.0 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO17536.1 - 0.0095 15.6 0.0 8.9 6.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO17536.1 - 0.0096 16.0 7.4 0.21 11.7 1.4 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 RNA_pol_A_CTD PF03118.10 EDO17536.1 - 0.021 14.2 0.0 0.2 11.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain TPR_1 PF00515.23 EDO17536.1 - 0.027 14.1 5.0 1.6 8.5 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDO17536.1 - 0.043 14.1 0.1 6.8 7.1 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.12 EDO17537.1 - 3.8e-104 348.9 35.6 4.8e-104 348.6 24.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family HECT PF00632.20 EDO17538.1 - 6.4e-89 298.2 1.3 1.4e-88 297.1 0.9 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Aldedh PF00171.17 EDO17539.1 - 3.7e-148 493.7 0.0 4.2e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EDO17539.1 - 0.0019 17.0 0.0 0.047 12.4 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) Tup_N PF08581.5 EDO17540.1 - 0.00042 20.4 10.1 0.00042 20.4 7.0 2.9 1 1 1 3 3 3 1 Tup N-terminal HrpB7 PF09486.5 EDO17540.1 - 0.0068 16.3 1.4 0.017 15.0 1.0 1.6 1 1 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) DUF948 PF06103.6 EDO17540.1 - 0.013 15.3 1.3 0.013 15.3 0.9 3.6 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3450 PF11932.3 EDO17540.1 - 0.06 12.6 18.7 0.068 12.4 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Filament PF00038.16 EDO17540.1 - 0.064 12.7 34.9 0.27 10.6 24.0 2.1 1 1 0 1 1 1 0 Intermediate filament protein Spectrin PF00435.16 EDO17540.1 - 0.42 10.9 18.6 0.57 10.4 1.6 3.0 1 1 2 3 3 3 0 Spectrin repeat DUF4200 PF13863.1 EDO17540.1 - 2.4 8.1 28.9 1.9 8.4 8.6 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 EDO17540.1 - 3.5 6.7 12.0 0.35 9.9 4.0 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EDO17541.1 - 7.9e-51 172.7 12.2 1.2e-50 172.2 8.4 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF2853 PF11015.3 EDO17541.1 - 0.019 15.4 2.6 0.029 14.8 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2853) DP PF08781.5 EDO17541.1 - 0.032 13.9 7.4 0.44 10.2 0.4 2.5 1 1 1 2 2 2 0 Transcription factor DP IncA PF04156.9 EDO17541.1 - 4.8 6.7 8.1 8.2 5.9 5.6 1.4 1 0 0 1 1 1 0 IncA protein AA_permease PF00324.16 EDO17543.1 - 8.7e-119 396.9 43.3 9.9e-119 396.7 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO17543.1 - 5.5e-32 110.8 45.8 7e-32 110.5 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease UCH PF00443.24 EDO17544.1 - 5.7e-53 179.7 4.9 7.1e-53 179.4 3.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO17544.1 - 1.1e-18 67.6 11.2 2.5e-18 66.5 7.8 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EDO17544.1 - 2.9e-05 23.3 0.2 0.00016 20.9 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family GSHPx PF00255.14 EDO17545.1 - 4.3e-44 148.3 0.1 5.7e-44 147.9 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Redoxin PF08534.5 EDO17545.1 - 6.4e-06 25.7 0.0 2.5e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EDO17545.1 - 0.00044 19.9 0.1 0.0013 18.4 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family WD40 PF00400.27 EDO17546.1 - 2e-33 113.0 19.8 2.8e-09 36.5 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat YmzC PF14157.1 EDO17546.1 - 0.022 14.5 0.0 4.4 7.2 0.0 3.5 3 0 0 3 3 3 0 YmzC-like protein Apc4_WD40 PF12894.2 EDO17546.1 - 0.035 13.6 0.1 19 4.8 0.0 3.9 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Glycos_transf_4 PF00953.16 EDO17547.1 - 5.9e-29 100.9 10.5 5.9e-29 100.9 7.3 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 4 Sugar_tr PF00083.19 EDO17548.1 - 4.9e-92 308.8 26.0 6.8e-92 308.3 18.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO17548.1 - 6.9e-33 113.8 45.7 8.3e-31 106.9 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EDO17548.1 - 0.00049 18.6 2.5 0.00049 18.6 1.7 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein Cys_rich_VLP PF14194.1 EDO17548.1 - 0.13 12.0 0.1 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Cysteine-rich VLP Zn_clus PF00172.13 EDO17549.1 - 4.3e-09 36.1 9.6 4.3e-09 36.1 6.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MVP_shoulder PF11978.3 EDO17549.1 - 0.054 13.3 0.3 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Shoulder domain DEAD PF00270.24 EDO17551.1 - 1.2e-43 148.5 0.3 3.8e-43 146.8 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO17551.1 - 3.9e-18 65.0 0.0 1.4e-17 63.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDO17551.1 - 1.2e-06 27.6 0.0 1.2e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Pox_MCEL PF03291.11 EDO17552.1 - 3.2e-97 325.3 0.1 4.7e-97 324.8 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 EDO17552.1 - 3.2e-08 33.4 0.0 5.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO17552.1 - 3.5e-08 34.0 0.0 9.1e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO17552.1 - 4.6e-08 33.4 0.0 1.3e-07 31.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO17552.1 - 4.8e-08 33.3 0.0 2.8e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO17552.1 - 2.1e-07 30.6 0.0 4.5e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO17552.1 - 6e-06 26.5 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EDO17552.1 - 0.00087 18.3 0.0 0.0021 17.1 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EDO17552.1 - 0.015 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EDO17552.1 - 0.037 13.1 1.2 0.081 11.9 0.0 1.9 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase TPMT PF05724.6 EDO17552.1 - 0.046 13.1 0.0 0.093 12.1 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.12 EDO17552.1 - 0.05 12.5 0.0 0.13 11.2 0.0 1.6 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family MetW PF07021.7 EDO17552.1 - 0.098 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AA_permease PF00324.16 EDO17553.1 - 9.9e-45 152.7 37.7 1.3e-44 152.3 26.1 1.1 1 0 0 1 1 1 1 Amino acid permease Me-amine-dh_H PF06433.6 EDO17554.1 - 0.091 11.3 0.1 0.23 10.0 0.0 1.6 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) KH_1 PF00013.24 EDO17555.1 - 8.5e-36 121.4 3.4 1e-11 44.2 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EDO17555.1 - 6.2e-25 86.3 7.5 4e-09 35.9 0.6 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EDO17555.1 - 4.2e-09 35.8 0.4 0.083 12.4 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EDO17555.1 - 1.5e-06 27.6 0.5 0.034 13.7 0.0 3.5 3 0 0 3 3 3 2 KH domain ABC1 PF03109.11 EDO17556.1 - 5.9e-38 129.5 0.0 1.3e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 ABC1 family HA2 PF04408.18 EDO17557.1 - 8e-27 93.2 0.1 1.7e-26 92.2 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDO17557.1 - 1.5e-25 89.2 0.0 3.8e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDO17557.1 - 1.7e-12 47.0 0.0 3.4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO17557.1 - 6.4e-10 38.7 0.5 1.1e-09 38.0 0.4 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO17557.1 - 1e-06 28.8 0.1 4.3e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EDO17557.1 - 1.4e-05 24.6 0.3 3.3e-05 23.4 0.2 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EDO17557.1 - 0.00012 21.9 0.2 0.0054 16.5 0.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EDO17557.1 - 0.0002 21.1 0.2 0.00037 20.2 0.1 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_23 PF13476.1 EDO17557.1 - 0.0094 16.2 0.0 0.056 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EDO17557.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EDO17557.1 - 0.027 13.3 0.0 0.055 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EDO17557.1 - 0.094 11.9 0.2 0.3 10.2 0.1 2.0 1 1 0 1 1 1 0 PhoH-like protein Response_reg PF00072.19 EDO17557.1 - 0.098 12.6 0.4 2 8.4 0.1 2.9 3 0 0 3 3 3 0 Response regulator receiver domain AAA_29 PF13555.1 EDO17557.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EDO17557.1 - 0.13 12.1 0.1 0.49 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Nab2 PF11517.3 EDO17558.1 - 2.8e-50 168.9 3.4 4.5e-50 168.2 2.4 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.1 EDO17558.1 - 2.8e-12 46.1 67.4 1.1e-05 25.2 2.3 7.6 7 1 0 7 7 7 5 Zinc finger C-x8-C-x5-C-x3-H type DUF2360 PF10152.4 EDO17558.1 - 0.0068 16.6 9.3 0.0068 16.6 6.5 1.8 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) DUF2508 PF10704.4 EDO17558.1 - 0.015 15.4 0.1 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Nucleo_P87 PF07267.6 EDO17558.1 - 0.05 12.2 5.1 0.075 11.7 3.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PAT1 PF09770.4 EDO17558.1 - 0.066 11.4 24.1 0.11 10.7 16.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EDO17558.1 - 3.9 7.2 17.6 10 5.8 12.2 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAP PF07174.6 EDO17558.1 - 4.9 6.3 24.0 0.054 12.7 9.9 2.3 3 0 0 3 3 3 0 Fibronectin-attachment protein (FAP) LcrG PF07216.7 EDO17558.1 - 6.6 6.8 7.4 8.5 6.4 1.4 2.5 2 0 0 2 2 2 0 LcrG protein Ribosomal_S5 PF00333.15 EDO17559.1 - 2.2e-28 97.7 5.1 3.2e-28 97.2 1.5 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EDO17559.1 - 1.8e-21 75.1 0.1 3.1e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PAT1 PF09770.4 EDO17560.1 - 4 5.5 29.7 5.3 5.1 20.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SelP_N PF04592.9 EDO17560.1 - 4.2 6.6 20.0 0.24 10.7 1.9 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Glyco_hydro_31 PF01055.21 EDO17561.1 - 1.6e-135 452.4 0.0 2.4e-135 451.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EDO17561.1 - 2.1e-24 85.1 0.1 8.5e-24 83.2 0.1 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like DUF1947 PF09183.5 EDO17561.1 - 2.1 8.1 8.0 1.2 8.9 0.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) Tyr-DNA_phospho PF06087.7 EDO17562.1 - 1.7e-122 409.2 3.5 2e-122 409.0 2.4 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase AMP-binding PF00501.23 EDO17563.1 - 2.7e-71 240.1 0.0 3.8e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO17563.1 - 1.7e-13 51.3 0.0 5.5e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GAF_3 PF13492.1 EDO17563.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 GAF domain Transket_pyr PF02779.19 EDO17564.1 - 1.9e-47 161.0 0.0 4.1e-47 159.9 0.0 1.5 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDO17564.1 - 8.9e-37 125.7 0.0 1.8e-36 124.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Symplekin_C PF12295.3 EDO17565.1 - 0.036 13.9 0.2 0.06 13.2 0.1 1.3 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal TPD52 PF04201.10 EDO17565.1 - 0.048 13.3 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Tumour protein D52 family CPSase_L_D2 PF02786.12 EDO17566.1 - 5.6e-83 277.3 0.4 9.8e-83 276.5 0.3 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EDO17566.1 - 2.2e-65 219.7 0.0 3.7e-65 219.0 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EDO17566.1 - 4.1e-34 116.9 0.0 1.2e-33 115.4 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EDO17566.1 - 9.1e-33 112.4 0.0 7.8e-31 106.2 0.0 2.9 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EDO17566.1 - 1e-28 100.5 0.1 2.2e-28 99.5 0.1 1.5 1 0 0 1 1 1 1 HMGL-like ATPgrasp_Ter PF15632.1 EDO17566.1 - 1.5e-20 73.2 0.0 6.4e-20 71.1 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EDO17566.1 - 1.6e-18 66.0 2.9 1.6e-18 66.0 2.0 2.9 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EDO17566.1 - 3.1e-16 59.6 0.3 5.9e-16 58.7 0.2 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EDO17566.1 - 2.3e-09 36.7 2.3 2.5e-05 23.8 0.1 3.2 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 EDO17566.1 - 4.4e-07 29.3 0.1 8.9e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EDO17566.1 - 6.7e-07 28.8 0.0 1.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EDO17566.1 - 7.9e-07 28.7 0.0 2.2e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EDO17566.1 - 1.3e-05 25.1 0.0 2.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EDO17566.1 - 2.4e-05 23.8 1.9 0.094 12.0 0.0 2.8 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_3 PF13437.1 EDO17566.1 - 0.0055 17.0 0.6 0.15 12.3 0.1 3.3 2 1 1 3 3 3 1 HlyD family secretion protein RnfC_N PF13375.1 EDO17566.1 - 0.21 11.3 2.2 1.7 8.4 0.3 3.0 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain APG12 PF04110.8 EDO17567.1 - 7.3e-32 109.4 0.2 1.1e-31 108.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF4368 PF14287.1 EDO17567.1 - 0.06 13.1 0.0 0.096 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) Kinetochor_Ybp2 PF08568.5 EDO17568.1 - 1.7e-166 555.2 21.0 1.9e-166 555.0 14.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HUN PF08729.5 EDO17569.1 - 3.1e-13 49.3 0.1 3.1e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 HPC2 and ubinuclein domain PP2C PF00481.16 EDO17570.1 - 6e-56 189.6 0.1 1e-55 188.9 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EDO17570.1 - 3.1e-45 151.1 97.2 2.9e-09 36.3 2.4 14.2 7 3 6 13 13 13 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO17570.1 - 2e-43 145.9 72.4 2.3e-08 33.6 3.9 9.9 4 2 7 11 11 11 10 Leucine rich repeat Guanylate_cyc PF00211.15 EDO17570.1 - 5.9e-28 97.4 0.0 1.3e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EDO17570.1 - 3.8e-24 81.0 69.6 0.03 14.3 0.9 19.7 17 2 1 18 18 18 9 Leucine Rich Repeat LRR_7 PF13504.1 EDO17570.1 - 4.2e-11 41.1 57.8 1.6 9.2 0.0 17.7 19 0 0 19 19 19 5 Leucine rich repeat RA PF00788.18 EDO17570.1 - 5.8e-07 29.9 0.0 1.5e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PP2C_2 PF13672.1 EDO17570.1 - 0.0047 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_6 PF13516.1 EDO17570.1 - 0.0079 16.1 79.1 0.2 11.8 0.6 16.9 16 2 2 18 18 16 4 Leucine Rich repeat LRR_9 PF14580.1 EDO17570.1 - 0.03 13.9 19.7 0.034 13.7 1.8 4.4 2 1 2 4 4 4 0 Leucine-rich repeat DUF2065 PF09838.4 EDO17570.1 - 0.61 9.8 0.0 1.3 8.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) SYS1 PF09801.4 EDO17571.1 - 5.4e-49 165.9 12.2 6.4e-49 165.6 8.4 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Oxidored_q2 PF00420.19 EDO17571.1 - 10 5.8 10.5 11 5.7 1.6 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DEAD PF00270.24 EDO17572.1 - 3.2e-46 156.8 0.1 1.1e-45 155.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO17572.1 - 2.2e-26 91.5 0.0 1.3e-25 89.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain COX16 PF14138.1 EDO17573.1 - 6.5e-31 106.3 0.4 6.5e-31 106.3 0.3 1.4 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 MFS_1 PF07690.11 EDO17573.1 - 0.053 12.2 0.0 0.064 11.9 0.0 1.0 1 0 0 1 1 1 0 Major Facilitator Superfamily Proteasome PF00227.21 EDO17575.1 - 8.7e-49 165.3 0.9 1e-48 165.1 0.6 1.0 1 0 0 1 1 1 1 Proteasome subunit KAT11 PF08214.6 EDO17576.1 - 1.9e-104 349.5 2.8 2.2e-104 349.2 1.9 1.0 1 0 0 1 1 1 1 Histone acetylation protein Ribosomal_L34 PF00468.12 EDO17576.1 - 0.077 12.6 1.7 0.16 11.6 1.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L34 Fasciclin PF02469.17 EDO17577.1 - 3.1e-18 66.0 11.2 3e-05 24.0 0.8 6.7 5 3 0 5 5 5 5 Fasciclin domain SKG6 PF08693.5 EDO17577.1 - 0.26 10.6 1.3 0.46 9.8 0.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Aa_trans PF01490.13 EDO17578.1 - 8.7e-82 274.7 25.7 1.1e-81 274.5 17.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ribosomal_S17 PF00366.15 EDO17580.1 - 1.4e-29 101.9 4.0 2.3e-29 101.2 2.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Myb_DNA-binding PF00249.26 EDO17581.1 - 6e-19 67.8 7.9 3.2e-09 36.6 0.3 3.8 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO17581.1 - 3.1e-17 62.4 15.4 2e-14 53.4 1.7 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EDO17581.1 - 0.24 11.5 22.5 0.043 13.9 7.0 4.6 3 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF2450 PF10475.4 EDO17582.1 - 1e-05 24.6 1.5 3.5e-05 22.8 1.0 1.9 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF1752 PF08550.5 EDO17583.1 - 1.8e-08 33.8 1.5 3.7e-08 32.8 1.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) WD40 PF00400.27 EDO17584.1 - 1.9e-21 75.1 0.6 1.6e-06 27.7 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat CHCH PF06747.8 EDO17585.1 - 4.7e-09 35.9 8.1 5.1e-05 23.0 0.9 2.3 2 0 0 2 2 2 2 CHCH domain Cmc1 PF08583.5 EDO17585.1 - 0.00021 20.9 9.3 0.0079 15.9 1.2 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 EDO17585.1 - 0.0012 18.6 8.3 0.11 12.3 2.2 3.2 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0203) GCK PF07802.6 EDO17585.1 - 0.0055 16.8 5.3 0.098 12.7 0.2 2.4 1 1 1 2 2 2 2 GCK domain COX6B PF02297.12 EDO17585.1 - 0.019 14.9 7.7 0.077 13.0 3.2 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EDO17585.1 - 0.097 12.7 10.3 0.55 10.3 2.7 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 PolC_DP2 PF03833.8 EDO17585.1 - 0.22 9.1 3.1 0.24 9.0 2.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 COX17 PF05051.8 EDO17585.1 - 0.52 10.3 9.2 9.6 6.3 1.6 3.5 2 1 2 4 4 4 0 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.11 EDO17585.1 - 0.8 9.6 6.1 11 6.0 0.4 2.9 1 1 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein NDUF_B7 PF05676.8 EDO17585.1 - 3.9 6.9 7.7 4 6.9 0.5 2.8 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) FMN_red PF03358.10 EDO17586.1 - 1.2e-12 47.5 0.0 1.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EDO17586.1 - 9.4e-06 25.6 0.2 3.1e-05 23.9 0.1 1.9 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EDO17586.1 - 1.7e-05 24.4 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EDO17586.1 - 0.015 15.3 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Flavodoxin domain SGL PF08450.7 EDO17587.1 - 6e-45 153.5 0.1 9.1e-45 152.9 0.1 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Coatomer_WDAD PF04053.9 EDO17587.1 - 0.0047 15.7 0.6 0.029 13.1 0.1 1.9 1 1 0 2 2 2 1 Coatomer WD associated region MRJP PF03022.11 EDO17587.1 - 0.062 12.5 0.1 0.71 9.0 0.0 2.1 2 0 0 2 2 2 0 Major royal jelly protein Bac_rhodopsin PF01036.13 EDO17588.1 - 7.6e-44 149.6 18.9 9.2e-44 149.3 13.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4010 PF13194.1 EDO17588.1 - 0.021 14.0 2.9 1.6 7.9 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4010) DUF4131 PF13567.1 EDO17588.1 - 1.8 7.9 9.3 0.4 10.0 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1230 PF06799.6 EDO17588.1 - 8.2 6.2 8.9 8.5 6.2 1.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1230) Fungal_trans_2 PF11951.3 EDO17589.1 - 2.7e-20 72.3 2.0 1.1e-19 70.3 1.4 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO17589.1 - 3.4e-06 26.8 12.7 3.4e-06 26.8 8.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP1_N PF06424.7 EDO17590.1 - 4.1e-33 114.5 1.0 4.1e-33 114.5 0.7 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.1 EDO17590.1 - 6.2e-14 52.0 0.1 0.057 13.7 0.0 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDO17590.1 - 2.2e-13 49.5 0.0 1.8 9.3 0.0 8.4 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO17590.1 - 1.5e-11 44.6 0.0 0.087 13.5 0.0 5.7 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDO17590.1 - 6e-10 38.6 0.2 0.021 14.4 0.0 5.3 3 1 1 5 5 5 4 TPR repeat ChAPs PF09295.5 EDO17590.1 - 1.3e-07 30.7 7.7 0.00049 18.9 1.1 3.2 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) Apc3 PF12895.2 EDO17590.1 - 4.2e-05 23.5 1.9 0.0034 17.4 0.0 3.3 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EDO17590.1 - 0.00012 21.8 0.7 0.39 10.6 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDO17590.1 - 0.00072 19.5 4.5 1.8 8.9 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat Suf PF05843.9 EDO17590.1 - 0.0011 18.7 1.1 0.0011 18.7 0.8 3.2 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_8 PF13181.1 EDO17590.1 - 0.028 14.2 4.2 0.36 10.7 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Cellulase PF00150.13 EDO17591.1 - 4.7e-10 39.1 4.6 8.3e-10 38.3 3.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rogdi_lz PF10259.4 EDO17592.1 - 0.33 10.0 16.5 0.93 8.5 3.8 2.3 1 1 1 2 2 2 0 Rogdi leucine zipper containing protein DUF948 PF06103.6 EDO17592.1 - 1.3 8.9 15.3 0.083 12.7 0.5 3.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GPI-anchored PF10342.4 EDO17592.1 - 4.1 7.9 7.4 1.8 9.1 1.9 2.7 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-C2H2_6 PF13912.1 EDO17593.1 - 0.072 13.0 1.0 0.16 11.9 0.7 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-CCHC_4 PF14392.1 EDO17593.1 - 0.82 9.3 5.7 0.32 10.7 1.5 2.2 2 0 0 2 2 2 0 Zinc knuckle PIP5K PF01504.13 EDO17594.1 - 1.2e-81 273.5 5.5 1.2e-81 273.5 3.8 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Zn_clus PF00172.13 EDO17595.1 - 6.4e-09 35.5 9.3 1.4e-08 34.4 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.10 EDO17596.1 - 6.4e-73 245.7 40.1 8.5e-73 245.3 27.8 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Clat_adaptor_s PF01217.15 EDO17597.1 - 4.4e-56 188.5 4.6 5.1e-56 188.3 3.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.15 EDO17598.1 - 1.1e-22 80.7 0.0 1.7e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 EDO17598.1 - 0.024 14.3 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) MAGE PF01454.14 EDO17598.1 - 0.1 11.8 0.1 0.16 11.3 0.0 1.4 1 1 0 1 1 1 0 MAGE family ABC1 PF03109.11 EDO17600.1 - 2.5e-32 111.3 0.0 4.9e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EDO17600.1 - 2.2e-05 23.8 0.1 0.00035 19.9 0.0 2.6 3 0 0 3 3 3 1 RIO1 family OCD_Mu_crystall PF02423.10 EDO17601.1 - 4.7e-09 35.4 0.0 7.6e-05 21.6 0.0 2.1 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Zn_clus PF00172.13 EDO17602.1 - 2.4e-08 33.7 8.6 5.1e-08 32.7 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDO17602.1 - 1.6e-07 30.4 2.0 4e-07 29.1 1.4 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain XRCC1_N PF01834.11 EDO17602.1 - 0.0098 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 1 XRCC1 N terminal domain Pirin PF02678.11 EDO17603.1 - 4.1e-29 100.6 0.1 4.2e-28 97.3 0.1 2.1 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 EDO17603.1 - 1e-15 57.6 0.0 6.2e-15 55.1 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EDO17603.1 - 3.3e-06 26.5 1.3 1.5e-05 24.3 0.4 2.1 2 0 0 2 2 2 1 Cupin domain HAD PF12710.2 EDO17605.1 - 5.6e-25 88.6 0.1 9.8e-25 87.8 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO17605.1 - 1.3e-23 84.5 0.0 4.7e-23 82.7 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EDO17605.1 - 1e-17 63.9 0.0 2.4e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EDO17605.1 - 3.4e-07 30.1 0.0 7.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EDO17605.1 - 0.00066 19.3 2.8 0.0018 17.8 0.3 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EDO17605.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase HSP70 PF00012.15 EDO17606.1 - 1.9e-266 884.8 15.6 2.1e-266 884.6 10.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO17606.1 - 4.3e-15 55.1 4.2 3e-13 49.0 0.9 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EDO17606.1 - 0.00065 19.3 0.1 0.0024 17.4 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2797 PF10977.3 EDO17606.1 - 0.068 12.7 3.0 0.14 11.7 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) FtsA PF14450.1 EDO17606.1 - 0.19 11.5 12.6 4.2 7.2 1.8 4.4 4 1 0 4 4 4 0 Cell division protein FtsA Hydantoinase_A PF01968.13 EDO17606.1 - 1.2 8.2 10.8 0.22 10.5 0.1 3.4 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase Vps55 PF04133.9 EDO17607.1 - 7e-43 145.2 6.9 8.1e-43 144.9 4.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2142 PF09913.4 EDO17607.1 - 0.0076 14.9 0.0 0.01 14.5 0.0 1.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2142) DUF2085 PF09858.4 EDO17607.1 - 0.047 13.7 0.9 0.085 12.9 0.1 1.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2085) DUF1049 PF06305.6 EDO17607.1 - 1.3 8.5 7.3 4.6 6.7 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) A2M_comp PF07678.9 EDO17608.1 - 0.43 9.7 4.9 0.62 9.2 2.6 1.7 1 1 1 2 2 2 0 A-macroglobulin complement component EMP24_GP25L PF01105.19 EDO17609.1 - 2.2e-51 174.2 0.8 2.5e-51 174.0 0.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Remorin_C PF03763.8 EDO17609.1 - 0.16 11.5 4.3 0.28 10.7 3.0 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region WD40 PF00400.27 EDO17610.1 - 9.3e-18 63.3 6.0 1.3e-08 34.4 1.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EDO17610.1 - 1.8e-05 24.5 2.0 0.0012 18.6 0.0 3.2 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EDO17610.1 - 0.015 13.6 0.0 0.039 12.2 0.0 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain WD40 PF00400.27 EDO17611.1 - 6.3e-33 111.4 2.0 3.5e-08 33.0 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EDO17611.1 - 1.4e-06 28.1 0.3 0.002 17.8 0.1 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Fungal_trans PF04082.13 EDO17612.1 - 1.2e-07 30.9 1.2 2e-07 30.1 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO17612.1 - 9.9e-06 25.3 6.4 9.9e-06 25.3 4.4 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COG5 PF10392.4 EDO17613.1 - 0.001 19.0 2.6 0.088 12.7 0.1 3.2 2 1 1 3 3 3 1 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.4 EDO17613.1 - 0.018 14.9 0.2 0.053 13.3 0.0 1.8 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GP41 PF00517.12 EDO17613.1 - 0.022 14.3 0.2 0.087 12.3 0.1 1.8 1 1 0 2 2 2 0 Retroviral envelope protein CompInhib_SCIN PF11546.3 EDO17613.1 - 0.025 14.4 1.1 4 7.3 0.1 2.6 2 1 0 2 2 2 0 Staphylococcal complement inhibitor SCIN PI-PLC-X PF00388.14 EDO17613.1 - 0.054 12.8 0.2 0.08 12.3 0.1 1.6 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain BLOC1_2 PF10046.4 EDO17613.1 - 0.43 10.7 3.8 1.5 8.9 0.0 3.2 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 E1-E2_ATPase PF00122.15 EDO17614.1 - 8.4e-56 188.5 1.0 8.4e-56 188.5 0.7 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDO17614.1 - 1.8e-41 141.6 8.1 1.8e-41 141.6 5.6 3.0 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDO17614.1 - 3.1e-24 86.5 0.0 2.9e-18 67.0 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO17614.1 - 1.3e-16 60.3 0.0 2.7e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EDO17614.1 - 2.4e-14 52.5 0.0 7.7e-14 50.9 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EDO17614.1 - 6.6e-14 52.5 0.0 1.4e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDO17614.1 - 4.1e-05 23.2 0.3 0.0009 18.8 0.2 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EDO17614.1 - 0.016 15.1 1.3 0.045 13.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) tRNA_int_endo PF01974.12 EDO17615.1 - 3.4e-10 39.5 0.0 7.9e-10 38.4 0.0 1.5 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain PUF PF00806.14 EDO17616.1 - 1.4e-65 213.2 9.8 2e-09 36.4 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF2305 PF10230.4 EDO17616.1 - 0.047 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Fungal_trans PF04082.13 EDO17617.1 - 2.5e-21 75.7 9.7 2.5e-21 75.7 6.7 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO17617.1 - 1.2e-07 31.5 11.1 2.6e-07 30.4 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.12 EDO17618.1 - 1.8e-176 586.9 30.5 2.1e-176 586.7 21.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CHD5 PF04420.9 EDO17618.1 - 0.73 9.4 5.1 2.1 7.9 3.6 1.8 1 0 0 1 1 1 0 CHD5-like protein Rsc14 PF08586.5 EDO17619.1 - 2.3e-44 150.0 0.9 2.3e-44 150.0 0.6 1.6 2 0 0 2 2 2 1 RSC complex, Rsc14/Ldb7 subunit Proteasome PF00227.21 EDO17620.1 - 2.2e-42 144.5 0.0 3.3e-42 143.9 0.0 1.3 1 1 1 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO17620.1 - 1.9e-15 55.8 0.1 3.4e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF962 PF06127.6 EDO17621.1 - 2e-24 85.3 5.1 6.2e-24 83.7 3.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF2910 PF11139.3 EDO17622.1 - 0.11 11.6 0.1 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) PgaD PF13994.1 EDO17622.1 - 0.13 11.7 0.7 0.33 10.4 0.5 1.6 1 0 0 1 1 1 0 PgaD-like protein PMP1_2 PF08114.6 EDO17623.1 - 8.4e-27 92.3 5.2 9e-27 92.3 3.6 1.0 1 0 0 1 1 1 1 ATPase proteolipid family DUF1049 PF06305.6 EDO17623.1 - 0.0083 15.5 0.7 0.01 15.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) HIG_1_N PF04588.8 EDO17623.1 - 0.041 13.6 0.1 0.047 13.4 0.1 1.1 1 0 0 1 1 1 0 Hypoxia induced protein conserved region DUF533 PF04391.7 EDO17623.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF533) RELT PF12606.3 EDO17623.1 - 0.36 9.9 2.0 0.42 9.7 1.4 1.1 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 TPP_enzyme_N PF02776.13 EDO17624.1 - 2.6e-32 111.6 0.0 3.8e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EDO17624.1 - 5.4e-22 78.0 0.0 3.8e-21 75.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EDO17624.1 - 6.5e-19 68.0 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.1 EDO17624.1 - 0.02 13.8 0.2 5.7 5.7 0.1 2.8 3 0 0 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase 14-3-3 PF00244.15 EDO17625.1 - 3.4e-114 379.8 6.0 4e-114 379.5 4.2 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF885 PF05960.6 EDO17625.1 - 0.0065 15.6 0.5 0.0065 15.6 0.3 1.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF885) FlaF PF07309.6 EDO17625.1 - 0.043 13.6 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF COPI_assoc PF08507.5 EDO17626.1 - 1.7e-38 131.4 7.9 2e-38 131.2 5.5 1.0 1 0 0 1 1 1 1 COPI associated protein Peptidase_M24 PF00557.19 EDO17627.1 - 3.9e-08 33.1 0.0 7.8e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Ste5_C PF12194.3 EDO17628.1 - 9.8e-93 309.1 0.3 9.8e-93 309.1 0.2 2.0 2 0 0 2 2 2 1 Protein kinase Fus3-binding zf-RING_2 PF13639.1 EDO17628.1 - 3.6e-06 26.7 2.6 7e-06 25.7 1.8 1.5 1 0 0 1 1 1 1 Ring finger domain PH_10 PF15411.1 EDO17628.1 - 0.0003 20.9 2.8 0.00048 20.3 0.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain zf-C3HC4_2 PF13923.1 EDO17628.1 - 0.0048 16.8 4.1 0.013 15.4 2.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EDO17628.1 - 0.14 11.8 2.7 0.4 10.4 1.9 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 EDO17628.1 - 0.29 10.8 5.1 0.71 9.6 3.5 1.7 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO17628.1 - 0.45 10.2 3.5 0.68 9.6 1.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Candida_ALS_N PF11766.3 EDO17629.1 - 1.1e-76 257.0 5.8 1.9e-76 256.2 4.0 1.4 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding Flocculin PF00624.13 EDO17629.1 - 1.1e-16 60.3 55.9 1.2e-09 37.7 15.7 3.5 4 0 0 4 4 4 2 Flocculin repeat Ssl1 PF04056.9 EDO17630.1 - 6.2e-87 290.1 0.0 8.8e-87 289.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EDO17630.1 - 9.4e-22 76.7 10.6 9.4e-22 76.7 7.3 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EDO17630.1 - 2.5e-14 53.7 0.0 3.4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EDO17630.1 - 0.0017 18.0 0.0 0.0048 16.6 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain zf-HIT PF04438.11 EDO17630.1 - 1.2 8.8 20.5 0.45 10.1 4.3 3.4 3 0 0 3 3 3 0 HIT zinc finger MFS_1 PF07690.11 EDO17631.1 - 9.8e-28 96.8 22.5 2.8e-27 95.3 15.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily FERM_C PF09380.5 EDO17631.1 - 0.034 14.3 0.1 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 FERM C-terminal PH-like domain Response_reg PF00072.19 EDO17632.1 - 8.4e-21 74.0 0.0 7.4e-14 51.7 0.0 2.4 1 1 1 2 2 2 2 Response regulator receiver domain SMC_Nse1 PF07574.8 EDO17633.1 - 1.3e-47 162.0 0.2 1.6e-47 161.7 0.1 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EDO17633.1 - 1.1e-09 38.1 12.8 2.3e-09 37.1 8.9 1.6 1 0 0 1 1 1 1 RING-like domain Coronavirus_5 PF05528.6 EDO17633.1 - 0.15 11.9 0.9 0.35 10.7 0.4 1.8 2 0 0 2 2 2 0 Coronavirus gene 5 protein DnaJ PF00226.26 EDO17634.1 - 1.5e-06 27.8 0.1 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EDO17634.1 - 1.1e-05 25.1 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Pam16 Proteasome PF00227.21 EDO17634.1 - 0.098 11.9 0.0 0.18 11.0 0.0 1.4 1 1 0 1 1 1 0 Proteasome subunit Ribosomal_L24e PF01246.15 EDO17635.1 - 1.6e-29 101.5 1.7 3.9e-29 100.3 1.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Pilt PF15453.1 EDO17635.1 - 0.49 10.0 5.7 0.6 9.7 3.9 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions TFIIF_alpha PF05793.7 EDO17635.1 - 0.62 8.3 17.1 0.86 7.9 11.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nucleoplasmin PF03066.10 EDO17635.1 - 1.7 8.1 10.7 2.4 7.6 7.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin Ten1 PF12658.2 EDO17636.1 - 5.5e-22 77.8 0.1 6.6e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit SPRY PF00622.23 EDO17637.1 - 0.00022 21.2 0.1 0.0083 16.2 0.0 2.8 2 1 0 2 2 2 1 SPRY domain Peripla_BP_1 PF00532.16 EDO17637.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Secretin_N_2 PF07655.8 EDO17637.1 - 8.4 6.8 17.9 5.8 7.3 0.2 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain HSP70 PF00012.15 EDO17638.1 - 8e-267 886.0 12.6 9.1e-267 885.8 8.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO17638.1 - 9.2e-19 67.1 1.8 2.1e-17 62.7 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EDO17638.1 - 0.00064 18.9 2.6 0.097 11.7 0.0 3.3 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 EDO17638.1 - 0.0016 17.3 0.1 0.086 11.6 0.0 2.4 2 1 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 EDO17638.1 - 0.02 14.2 0.0 0.17 11.1 0.0 2.2 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 EDO17638.1 - 0.054 13.3 6.8 0.21 11.4 0.7 3.4 2 2 0 2 2 2 0 Cell division protein FtsA TMA7 PF09072.5 EDO17638.1 - 2.6 8.5 6.5 0.23 11.9 0.6 2.2 2 0 0 2 2 2 0 Translation machinery associated TMA7 FHA PF00498.21 EDO17639.1 - 3.1e-15 56.0 0.1 5.2e-15 55.3 0.0 1.5 1 1 0 1 1 1 1 FHA domain DEAD PF00270.24 EDO17640.1 - 3.4e-43 147.0 0.1 1.3e-42 145.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EDO17640.1 - 1.9e-24 84.9 0.1 4e-24 83.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EDO17640.1 - 6.3e-23 80.4 0.0 1.4e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EDO17640.1 - 0.00014 21.9 0.0 0.0006 19.8 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DsrH PF04077.7 EDO17640.1 - 0.063 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 DsrH like protein Vpu PF00558.14 EDO17640.1 - 0.34 10.5 2.0 1.2 8.6 1.4 1.9 1 0 0 1 1 1 0 Vpu protein Cyclin_N PF00134.18 EDO17641.1 - 2.9e-12 46.2 5.3 6.5e-12 45.1 3.3 1.9 1 1 0 1 1 1 1 Cyclin, N-terminal domain PPTA PF01239.17 EDO17642.1 - 2.3e-40 134.3 20.8 2.4e-08 32.9 0.5 6.5 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat HORMA PF02301.13 EDO17643.1 - 8.8e-45 152.7 0.1 1e-44 152.5 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EDO17643.1 - 0.0038 16.6 0.0 0.0059 16.0 0.0 1.5 1 1 0 1 1 1 1 Autophagy-related protein 13 DUF2959 PF11172.3 EDO17643.1 - 0.064 13.0 0.1 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) Vps53_N PF04100.7 EDO17644.1 - 1.5e-81 274.1 15.1 2.7e-81 273.3 10.4 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal Pkinase PF00069.20 EDO17645.1 - 6.1e-71 238.6 0.0 8.4e-71 238.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17645.1 - 1.8e-36 125.5 0.0 2.5e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EDO17645.1 - 8.8e-17 60.9 0.5 2.5e-16 59.5 0.4 1.8 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 EDO17645.1 - 0.0042 16.1 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDO17645.1 - 0.012 14.6 1.8 4.1 6.2 0.1 3.3 2 2 2 4 4 4 0 Kinase-like DNA_pol_B PF00136.16 EDO17646.1 - 8.5e-135 450.1 1.3 1.2e-134 449.6 0.9 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EDO17646.1 - 7.4e-90 301.0 0.9 1.2e-89 300.4 0.6 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EDO17646.1 - 5.7e-24 83.9 6.1 1.4e-23 82.6 4.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 EDO17646.1 - 2.3e-05 23.2 1.1 0.0013 17.4 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 EDO17646.1 - 0.00022 20.8 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EDO17646.1 - 0.003 17.4 0.9 0.029 14.1 0.2 2.8 2 1 0 2 2 2 1 RNase_H superfamily AMPKBI PF04739.10 EDO17647.1 - 2.6e-22 78.5 0.2 2.6e-22 78.5 0.2 3.5 3 1 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain PAP1 PF08601.5 EDO17648.1 - 3.4e-34 119.0 49.3 1.2e-33 117.3 13.6 3.2 1 1 2 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.16 EDO17648.1 - 1.3e-06 28.2 14.5 5.8e-06 26.1 10.1 2.1 1 1 0 1 1 1 1 bZIP transcription factor ACCA PF03255.9 EDO17648.1 - 0.034 13.6 2.3 0.079 12.5 1.6 1.6 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit bZIP_Maf PF03131.12 EDO17648.1 - 0.76 10.1 12.8 0.061 13.6 5.1 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor bZIP_2 PF07716.10 EDO17648.1 - 2.6 7.9 23.9 0.036 13.8 10.8 2.3 2 1 1 3 3 3 0 Basic region leucine zipper Sterol_MT_C PF08498.5 EDO17649.1 - 6.7e-30 102.8 0.7 9.9e-30 102.2 0.5 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EDO17649.1 - 8.3e-19 67.8 0.0 1.5e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO17649.1 - 1e-16 60.8 0.0 1.9e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO17649.1 - 1.6e-12 47.4 0.0 2.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO17649.1 - 4.7e-12 45.5 0.2 6.4e-12 45.1 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EDO17649.1 - 5.2e-11 42.8 0.1 1.5e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO17649.1 - 5.7e-11 42.6 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO17649.1 - 1.5e-10 41.6 0.0 6.2e-10 39.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO17649.1 - 6.9e-08 32.5 0.0 2e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO17649.1 - 1.5e-07 30.8 0.0 2.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.5 EDO17649.1 - 9.7e-07 28.4 0.1 1.5e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 EDO17649.1 - 0.0037 16.8 0.0 0.0067 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 EDO17649.1 - 0.036 13.2 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.13 EDO17649.1 - 0.036 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.9 EDO17649.1 - 0.069 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Sugar_tr PF00083.19 EDO17650.1 - 1.6e-25 89.6 35.4 4.6e-22 78.2 24.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO17650.1 - 2e-15 56.3 45.8 9.7e-09 34.3 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Kinesin PF00225.18 EDO17651.1 - 7e-99 330.6 10.1 9.5e-99 330.2 7.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 EDO17651.1 - 0.073 13.2 0.4 2 8.5 0.0 2.8 2 1 1 3 3 3 0 AAA domain Dynein_light PF01221.13 EDO17652.1 - 2.7e-34 117.0 0.0 3.1e-34 116.8 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 CS PF04969.11 EDO17652.1 - 0.077 13.5 0.2 0.11 13.0 0.1 1.2 1 0 0 1 1 1 0 CS domain PX PF00787.19 EDO17653.1 - 1.7e-15 56.7 0.5 9e-15 54.4 0.0 2.3 2 0 0 2 2 2 1 PX domain Cep57_MT_bd PF06657.8 EDO17653.1 - 6.2 6.8 12.1 1.7 8.6 0.2 3.4 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Abhydrolase_3 PF07859.8 EDO17654.1 - 3.5e-06 26.7 0.0 5.2e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO17654.1 - 7e-06 25.8 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO17654.1 - 0.0017 18.2 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO17654.1 - 0.015 14.8 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EDO17654.1 - 0.026 13.9 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF915 PF06028.6 EDO17654.1 - 0.036 13.1 0.5 0.057 12.4 0.3 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) eIF3g PF12353.3 EDO17655.1 - 3.2e-36 124.0 0.1 3.6e-36 123.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Rad33 PF08730.5 EDO17656.1 - 1.1e-40 138.8 9.0 6.3e-39 133.1 6.2 2.0 1 1 0 1 1 1 1 Rad33 EMP24_GP25L PF01105.19 EDO17657.1 - 2e-41 141.7 0.0 2.3e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD M16C_assoc PF08367.6 EDO17658.1 - 1.3e-76 256.7 0.8 2.2e-76 255.9 0.6 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EDO17658.1 - 3.2e-29 101.8 0.0 4.9e-19 68.7 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDO17658.1 - 1e-06 28.6 0.4 4.8e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) UBX PF00789.15 EDO17659.1 - 1.7e-13 50.3 0.0 5.2e-11 42.4 0.0 3.2 2 1 0 2 2 2 1 UBX domain UBA_4 PF14555.1 EDO17659.1 - 5.6e-09 35.3 0.0 1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain DUF2247 PF10004.4 EDO17659.1 - 0.0022 17.7 0.1 0.0022 17.7 0.1 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2247) PIG-S PF10510.4 EDO17660.1 - 9.8e-137 456.7 10.1 1.1e-136 456.5 7.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Lip_A_acyltrans PF03279.8 EDO17660.1 - 0.062 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial lipid A biosynthesis acyltransferase TAFII28 PF04719.9 EDO17661.1 - 4.3e-26 90.5 0.4 1.6e-24 85.4 0.3 2.4 2 0 0 2 2 2 2 hTAFII28-like protein conserved region PIG-P PF08510.7 EDO17662.1 - 3.2e-35 120.5 3.1 3.8e-35 120.2 2.1 1.0 1 0 0 1 1 1 1 PIG-P DUF2208 PF09973.4 EDO17662.1 - 0.067 12.4 0.2 0.087 12.0 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) T4_neck-protein PF11649.3 EDO17662.1 - 0.1 11.8 0.0 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 Virus neck protein DUF4131 PF13567.1 EDO17662.1 - 0.12 11.7 0.1 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2842 PF11003.3 EDO17662.1 - 0.14 12.0 6.1 1.9 8.4 4.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2842) TMEM247 PF15444.1 EDO17662.1 - 6.1 6.6 5.6 15 5.2 0.3 2.2 2 0 0 2 2 2 0 Transmembrane protein 247 DUF1217 PF06748.7 EDO17663.1 - 0.54 10.3 5.3 0.61 10.1 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1217) EamA PF00892.15 EDO17664.1 - 4.6e-10 39.6 41.5 4.2e-09 36.5 3.5 3.8 3 1 1 4 4 4 3 EamA-like transporter family TPT PF03151.11 EDO17664.1 - 2.8e-08 33.5 30.9 0.00046 19.8 8.5 2.9 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EDO17664.1 - 6.2e-05 23.1 0.9 6.2e-05 23.1 0.6 3.6 3 2 1 4 4 4 2 Multidrug resistance efflux transporter OST3_OST6 PF04756.8 EDO17665.1 - 6.8e-21 74.4 12.1 1.1e-20 73.8 8.4 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EDO17665.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin LRS4 PF10422.4 EDO17666.1 - 9.7e-28 97.1 16.2 9.7e-28 97.1 11.2 1.6 1 1 0 1 1 1 1 Monopolin complex subunit LRS4 Dsl1_C PF11989.3 EDO17666.1 - 0.0028 16.8 5.6 0.0042 16.3 3.9 1.2 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Sec20 PF03908.8 EDO17666.1 - 0.15 11.7 5.0 0.49 10.1 3.5 1.9 1 0 0 1 1 1 0 Sec20 DUF3573 PF12097.3 EDO17666.1 - 0.29 9.6 9.1 0.42 9.1 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TMPIT PF07851.8 EDO17666.1 - 0.91 8.5 5.3 1.5 7.8 3.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein FlxA PF14282.1 EDO17666.1 - 4.5 7.2 21.2 15 5.6 13.0 2.3 2 0 0 2 2 2 0 FlxA-like protein DGF-1_C PF11040.3 EDO17667.1 - 0.96 9.3 4.3 0.74 9.7 1.7 1.8 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus UDG PF03167.14 EDO17668.1 - 4.1e-25 88.0 0.0 5.8e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily AXH PF08517.7 EDO17668.1 - 0.097 12.8 0.6 0.21 11.7 0.4 1.6 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) DOT1 PF08123.8 EDO17669.1 - 3e-89 297.7 0.1 7.5e-89 296.4 0.1 1.7 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.15 EDO17669.1 - 0.037 13.1 0.0 0.076 12.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Pribosyltran PF00156.22 EDO17670.1 - 5.4e-20 71.3 0.0 6.6e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDO17670.1 - 0.0012 18.0 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_3 PF15610.1 EDO17670.1 - 0.064 12.1 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like Med13_C PF06333.7 EDO17671.1 - 1.2e-92 310.7 0.6 1.2e-92 310.7 0.4 2.8 2 1 0 2 2 2 1 Mediator complex subunit 13 C-terminal Daxx PF03344.10 EDO17671.1 - 3.2 6.1 23.6 5 5.4 16.3 1.2 1 0 0 1 1 1 0 Daxx Family DUF676 PF05057.9 EDO17672.1 - 2.5e-47 161.0 0.0 3.9e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EDO17672.1 - 6.6e-06 25.7 0.0 1.3e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 EDO17672.1 - 0.00054 19.1 0.0 0.00098 18.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 EDO17672.1 - 0.034 13.7 0.1 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein ECM11 PF15463.1 EDO17673.1 - 1.5e-29 103.0 0.6 1.5e-29 103.0 0.4 2.6 3 0 0 3 3 3 1 Extracellular mutant protein 11 Ribosomal_L4 PF00573.17 EDO17674.1 - 5.3e-41 140.1 0.0 7.4e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Homeobox PF00046.24 EDO17675.1 - 1.4e-16 59.8 7.6 3.4e-16 58.5 5.2 1.7 1 0 0 1 1 1 1 Homeobox domain Amdo_NSP PF12475.3 EDO17675.1 - 0.035 14.0 0.2 0.15 12.0 0.1 2.1 1 0 0 1 1 1 0 Amdovirus non-structural protein Homeobox_KN PF05920.6 EDO17675.1 - 0.17 11.6 0.1 0.17 11.6 0.1 3.6 4 0 0 4 4 4 0 Homeobox KN domain AhpC-TSA PF00578.16 EDO17676.1 - 8e-35 119.2 0.0 1.9e-34 118.0 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EDO17676.1 - 1e-18 67.2 0.1 1.8e-18 66.5 0.0 1.4 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.4 EDO17676.1 - 4.4e-12 45.4 0.5 1e-11 44.2 0.1 1.8 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin Rad60-SLD PF11976.3 EDO17677.1 - 0.032 13.9 0.4 0.16 11.6 0.0 2.5 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Ndc1_Nup PF09531.5 EDO17678.1 - 1.9e-143 479.0 26.6 4.2e-143 477.9 18.4 1.5 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup A_deaminase PF00962.17 EDO17679.1 - 1.9e-116 388.6 0.1 3.2e-116 387.8 0.1 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase Ricin_B_lectin PF00652.17 EDO17679.1 - 0.002 18.1 3.9 0.16 11.9 0.8 2.4 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain zf-DHHC PF01529.15 EDO17680.1 - 8.2e-27 93.7 5.1 8.2e-27 93.7 3.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase PgaD PF13994.1 EDO17680.1 - 0.0064 15.9 5.7 0.0064 15.9 0.5 2.5 2 0 0 2 2 2 1 PgaD-like protein FAM176 PF14851.1 EDO17681.1 - 7.1 6.2 10.2 0.16 11.6 1.1 2.6 3 0 0 3 3 3 0 FAM176 family Redoxin PF08534.5 EDO17682.1 - 2.4e-29 101.7 0.1 2.8e-29 101.5 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EDO17682.1 - 2e-07 30.7 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family NCU-G1 PF15065.1 EDO17682.1 - 0.087 11.4 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 TPT PF03151.11 EDO17683.1 - 1.3e-38 132.0 5.6 1.3e-38 132.0 3.9 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EDO17683.1 - 5.4e-10 38.6 5.7 5.4e-10 38.6 3.9 2.2 2 0 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.10 EDO17683.1 - 2.4e-05 23.5 1.4 0.0036 16.4 0.3 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 EDO17683.1 - 3.3e-05 23.9 27.9 0.00098 19.1 5.4 3.1 2 2 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EDO17683.1 - 8.2e-05 22.7 1.2 8.2e-05 22.7 0.8 2.9 3 0 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EDO17683.1 - 0.00028 19.8 0.7 0.00028 19.8 0.5 2.2 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UPF0546 PF10639.4 EDO17683.1 - 0.00062 19.5 9.5 0.13 12.1 0.6 2.7 2 0 0 2 2 2 2 Uncharacterised protein family UPF0546 Herpes_LMP1 PF05297.6 EDO17683.1 - 0.041 12.7 0.5 0.088 11.7 0.4 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF485 PF04341.7 EDO17683.1 - 0.1 12.2 8.1 1.5 8.5 0.6 3.5 3 0 0 3 3 3 0 Protein of unknown function, DUF485 p450 PF00067.17 EDO17684.1 - 2.4e-106 356.0 0.0 2.8e-106 355.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1016 PF06250.6 EDO17685.1 - 0.00048 19.1 0.3 0.00085 18.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1016) Sod_Fe_C PF02777.13 EDO17686.1 - 4.2e-34 116.5 0.2 7.5e-34 115.7 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EDO17686.1 - 1.4e-23 82.9 0.4 2.5e-23 82.0 0.3 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.2 EDO17686.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Med20 PF08612.6 EDO17687.1 - 4.2e-48 163.4 0.0 4.6e-48 163.2 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF2791 PF10923.3 EDO17687.1 - 0.0096 14.5 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 1 P-loop Domain of unknown function (DUF2791) DUF2745 PF10922.3 EDO17687.1 - 0.054 13.4 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2745) CTD_bind PF04818.8 EDO17688.1 - 1.7e-20 73.0 0.9 6.2e-20 71.1 0.6 2.1 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.3 EDO17688.1 - 0.00014 21.5 6.6 0.00026 20.6 0.6 2.7 3 0 0 3 3 3 2 CTD kinase subunit gamma CTK3 Aldedh PF00171.17 EDO17689.1 - 1.1e-123 412.9 0.0 1.3e-123 412.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Imm8 PF15560.1 EDO17689.1 - 0.029 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 8 RRF PF01765.14 EDO17690.1 - 3e-42 143.9 3.6 3.9e-42 143.5 2.5 1.2 1 0 0 1 1 1 1 Ribosome recycling factor Cytochrom_C_2 PF01322.15 EDO17690.1 - 0.14 12.7 1.6 0.77 10.3 0.6 2.1 2 0 0 2 2 2 0 Cytochrome C' DUF4337 PF14235.1 EDO17690.1 - 0.41 10.4 2.8 0.74 9.6 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Brr6_like_C_C PF10104.4 EDO17691.1 - 3.2e-34 117.3 5.3 4.8e-34 116.7 3.7 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Pyridoxal_deC PF00282.14 EDO17692.1 - 1.4e-21 76.4 0.0 2.2e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EDO17692.1 - 7.9e-06 24.8 0.0 4.4e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EDO17692.1 - 3.8e-05 22.9 0.0 6.7e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family HDA2-3 PF11496.3 EDO17693.1 - 1.8e-75 253.5 10.7 5.3e-75 251.9 7.4 1.9 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Dimeth_Pyl PF09505.5 EDO17693.1 - 0.11 10.7 0.1 0.18 10.0 0.1 1.2 1 0 0 1 1 1 0 Dimethylamine methyltransferase (Dimeth_PyL) DUF972 PF06156.8 EDO17693.1 - 0.24 11.7 15.6 0.081 13.2 2.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Atg14 PF10186.4 EDO17693.1 - 0.49 9.2 11.2 0.94 8.3 7.8 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sec23_trunk PF04811.10 EDO17694.1 - 3.7e-13 49.4 0.4 1.5e-12 47.4 0.1 1.9 1 1 1 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDO17694.1 - 0.024 14.0 0.2 0.093 12.1 0.0 2.1 2 0 0 2 2 2 0 Sec23/Sec24 helical domain Mhr1 PF12829.2 EDO17695.1 - 3.8e-37 126.0 2.0 6.7e-37 125.1 1.4 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination OSCP PF00213.13 EDO17696.1 - 2.4e-45 154.4 2.1 2.7e-45 154.3 1.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit AATF-Che1 PF13339.1 EDO17697.1 - 4.5e-30 104.4 7.2 4.5e-30 104.4 5.0 3.2 4 0 0 4 4 4 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 EDO17697.1 - 1.2e-29 102.2 0.1 1.2e-29 102.2 0.1 3.1 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal Dsh_C PF12316.3 EDO17697.1 - 2.8 8.0 7.9 1.2 9.1 1.9 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Pkinase PF00069.20 EDO17698.1 - 8e-61 205.4 0.0 9.5e-61 205.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17698.1 - 3.9e-31 108.0 0.0 4.7e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDO17698.1 - 0.0039 16.2 0.0 0.0062 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO17698.1 - 0.022 14.4 0.1 0.05 13.3 0.1 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family PIF1 PF05970.9 EDO17699.1 - 4.4e-52 177.2 6.8 1.5e-43 149.1 0.1 2.7 2 1 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.1 EDO17699.1 - 2.5e-17 63.1 0.0 9.4e-17 61.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDO17699.1 - 2.5e-07 30.8 0.5 2.4e-06 27.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain UvrD_C_2 PF13538.1 EDO17699.1 - 0.00053 20.1 0.3 0.048 13.7 0.0 3.1 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EDO17699.1 - 0.00095 19.1 0.4 0.65 9.9 0.0 3.3 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EDO17699.1 - 0.0012 18.6 0.2 0.014 15.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 EDO17699.1 - 0.0017 17.6 0.3 0.028 13.6 0.0 2.8 2 1 1 3 3 3 1 PhoH-like protein AAA PF00004.24 EDO17699.1 - 0.012 15.8 2.9 0.042 14.0 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EDO17699.1 - 0.022 13.6 0.1 0.022 13.6 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 EDO17699.1 - 0.025 14.3 0.5 0.055 13.2 0.4 1.7 1 0 0 1 1 1 0 Part of AAA domain Helicase_RecD PF05127.9 EDO17699.1 - 0.033 13.8 0.6 0.92 9.1 0.2 3.1 2 1 0 2 2 2 0 Helicase Mg_chelatase PF01078.16 EDO17699.1 - 0.093 11.8 0.1 0.27 10.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Calcipressin PF04847.7 EDO17700.1 - 2e-20 73.1 0.2 2.9e-20 72.6 0.1 1.4 1 1 0 1 1 1 1 Calcipressin Peptidase_M1 PF01433.15 EDO17701.1 - 2.7e-147 490.9 2.7 3.8e-147 490.4 1.9 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EDO17701.1 - 1e-88 297.6 1.6 2.3e-88 296.5 0.5 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EDO17701.1 - 1.4e-20 73.6 0.6 3.2e-20 72.4 0.4 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily HEAT_2 PF13646.1 EDO17701.1 - 0.0078 16.4 0.0 6 7.2 0.0 2.4 2 0 0 2 2 2 2 HEAT repeats HAD_2 PF13419.1 EDO17702.1 - 2.9e-11 43.9 0.0 4.7e-11 43.2 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDO17702.1 - 0.00024 20.7 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDO17702.1 - 0.0098 16.3 0.0 4.8 7.5 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDO17702.1 - 0.087 12.9 0.0 0.16 12.1 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF155 PF02582.9 EDO17703.1 - 2.2e-44 151.4 0.2 3.5e-44 150.7 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Inositol_P PF00459.20 EDO17704.1 - 4.7e-67 226.1 0.0 5.3e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family EXS PF03124.9 EDO17705.1 - 4.5e-73 246.2 31.3 6.7e-73 245.6 21.7 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EDO17705.1 - 2.5e-35 122.5 0.3 2.5e-35 122.5 0.2 1.8 2 0 0 2 2 2 1 SPX domain E1-E2_ATPase PF00122.15 EDO17706.1 - 1.2e-34 119.3 0.2 3.3e-34 117.9 0.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EDO17706.1 - 3.4e-13 50.5 0.0 3.1e-12 47.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EDO17706.1 - 2.5e-09 37.5 0.1 5.9e-09 36.3 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO17706.1 - 1.1e-07 31.7 0.0 3.1e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit B-block_TFIIIC PF04182.7 EDO17706.1 - 0.022 14.5 0.1 0.32 10.8 0.0 2.6 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Hydrolase_3 PF08282.7 EDO17706.1 - 0.028 14.0 0.0 0.028 14.0 0.0 3.5 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase Transp_cyt_pur PF02133.10 EDO17707.1 - 9e-85 284.8 36.1 1e-84 284.6 25.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Ribosomal_L34e PF01199.13 EDO17708.1 - 2e-35 120.8 5.8 2e-35 120.8 4.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L34e DUF1428 PF07237.6 EDO17708.1 - 0.09 12.6 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Ribonuc_L-PSP PF01042.16 EDO17709.1 - 3.8e-41 139.6 0.5 4.4e-41 139.4 0.4 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF4488 PF14869.1 EDO17709.1 - 0.028 13.9 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) Cyclin PF08613.6 EDO17710.1 - 8e-39 133.4 2.0 5.3e-24 85.3 0.3 2.9 2 1 1 3 3 3 2 Cyclin RP-C_C PF11800.3 EDO17710.1 - 0.012 15.2 0.4 0.02 14.6 0.3 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Gag_p10 PF02337.12 EDO17710.1 - 0.034 13.8 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Retroviral GAG p10 protein Zip PF02535.17 EDO17710.1 - 0.11 11.4 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 EDO17710.1 - 0.3 9.3 6.7 0.34 9.1 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Pex14_N PF04695.8 EDO17710.1 - 0.84 9.6 10.4 2.1 8.3 7.2 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2841 PF11001.3 EDO17711.1 - 2.3e-38 130.9 3.4 3.9e-38 130.1 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) Fungal_trans PF04082.13 EDO17712.1 - 2.7e-37 128.0 5.5 4.8e-37 127.2 3.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO17712.1 - 5.1e-09 35.8 10.8 1e-08 34.9 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DHHC PF01529.15 EDO17713.1 - 4.3e-25 88.0 24.8 4.1e-24 84.9 17.0 2.2 1 1 0 1 1 1 1 DHHC palmitoyltransferase DHQ_synthase PF01761.15 EDO17714.1 - 2.7e-68 229.7 0.2 4e-68 229.1 0.1 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EDO17714.1 - 9.5e-08 31.6 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EDO17714.1 - 0.031 12.9 0.0 0.079 11.5 0.0 1.6 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase WD40 PF00400.27 EDO17715.1 - 1.2e-12 47.1 21.7 1.3e-07 31.1 0.2 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 EDO17715.1 - 6.1e-05 22.8 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 EDO17715.1 - 0.002 17.9 12.0 0.0056 16.4 8.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO17715.1 - 0.087 12.9 10.9 0.057 13.5 5.8 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger Vps39_2 PF10367.4 EDO17715.1 - 0.15 12.2 1.9 0.44 10.7 1.3 1.8 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 EDO17715.1 - 2.5 8.2 15.5 6.1 6.9 10.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.20 EDO17716.1 - 1.8e-05 24.7 0.0 0.0057 16.5 0.0 2.2 1 1 0 2 2 2 2 short chain dehydrogenase Toxin_41 PF15521.1 EDO17716.1 - 0.079 12.1 0.3 0.16 11.1 0.2 1.4 1 0 0 1 1 1 0 Putative toxin 41 Apc9 PF12856.2 EDO17717.1 - 2.5e-22 78.8 0.4 2.5e-22 78.8 0.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 9 CDC45 PF02724.9 EDO17718.1 - 1.9e-222 739.7 2.6 2.2e-222 739.5 1.8 1.0 1 0 0 1 1 1 1 CDC45-like protein DUF2413 PF10310.4 EDO17718.1 - 0.0029 16.4 0.0 0.0029 16.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2413) YL1 PF05764.8 EDO17718.1 - 0.17 11.4 21.3 0.026 14.1 9.1 2.2 2 0 0 2 2 2 0 YL1 nuclear protein CENP-T PF15511.1 EDO17718.1 - 2.5 7.2 16.0 0.23 10.6 6.6 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T TFIIA PF03153.8 EDO17718.1 - 3.6 7.3 27.3 12 5.6 15.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RNase_T PF00929.19 EDO17720.1 - 1.6e-15 57.7 0.6 1.5e-14 54.5 0.1 2.3 2 0 0 2 2 2 1 Exonuclease CHORD PF04968.7 EDO17720.1 - 0.00074 19.7 4.0 0.0013 18.8 2.7 1.4 1 0 0 1 1 1 1 CHORD UPF0184 PF03670.8 EDO17721.1 - 0.08 13.1 0.4 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) BTB_2 PF02214.17 EDO17722.1 - 1.8e-09 37.6 0.3 3.8e-05 23.7 0.0 2.8 2 1 0 2 2 2 2 BTB/POZ domain ABC_membrane PF00664.18 EDO17723.1 - 6.4e-92 307.8 36.1 9.8e-54 182.6 4.6 2.6 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDO17723.1 - 6.4e-50 169.0 0.2 4.8e-31 107.8 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDO17723.1 - 9.2e-12 44.6 5.0 8.1e-07 28.4 0.7 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDO17723.1 - 3.3e-07 30.4 0.0 0.029 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EDO17723.1 - 2.8e-06 26.8 0.0 0.046 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EDO17723.1 - 3.3e-05 23.8 0.0 0.13 12.2 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EDO17723.1 - 7.8e-05 22.1 0.3 0.5 9.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EDO17723.1 - 0.00011 22.7 0.6 0.32 11.4 0.0 3.3 3 0 0 3 3 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EDO17723.1 - 0.00025 20.5 0.0 0.35 10.3 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 EDO17723.1 - 0.0027 16.9 0.1 1.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EDO17723.1 - 0.0028 17.1 4.7 2.3 7.5 0.1 3.3 2 1 0 3 3 3 1 AAA-like domain AAA_22 PF13401.1 EDO17723.1 - 0.0053 16.9 0.7 6.1 6.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EDO17723.1 - 0.0086 16.4 7.6 0.21 11.8 1.0 3.4 3 1 0 3 3 3 1 AAA domain Dynamin_N PF00350.18 EDO17723.1 - 0.018 14.8 0.8 0.52 10.1 0.0 2.7 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.12 EDO17723.1 - 0.037 13.8 7.4 0.28 10.9 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 MobB PF03205.9 EDO17723.1 - 0.05 13.3 1.8 7.1 6.3 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EDO17723.1 - 0.069 13.9 0.1 7.5 7.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EDO17723.1 - 0.16 11.0 0.4 9.6 5.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 EDO17723.1 - 0.27 10.7 0.3 18 4.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF4520 PF15016.1 EDO17723.1 - 0.48 10.0 2.2 1.9 8.1 0.0 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4520) AIG1 PF04548.11 EDO17723.1 - 6.6 5.7 9.8 0.38 9.8 0.1 3.0 3 0 0 3 3 3 0 AIG1 family Metallophos PF00149.23 EDO17724.1 - 7e-40 136.5 0.0 1.2e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UCH_1 PF13423.1 EDO17725.1 - 3.7e-44 151.3 8.3 6.1e-44 150.6 5.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EDO17725.1 - 6.7e-26 91.5 0.0 1.3e-25 90.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EDO17725.1 - 9.2e-11 41.3 7.1 2.2e-10 40.0 5.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Nup96 PF12110.3 EDO17726.1 - 6.5e-62 209.2 3.1 1.2e-61 208.3 2.1 1.5 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EDO17726.1 - 7.2e-51 171.7 0.0 1.6e-50 170.5 0.0 1.7 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EDO17726.1 - 1.7e-25 89.4 143.9 2.4e-13 50.2 32.1 4.6 1 1 3 4 4 4 3 Nucleoporin FG repeat region MF_alpha_N PF05436.6 EDO17727.1 - 2.2e-24 84.9 0.6 4.6e-24 83.9 0.4 1.6 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.7 EDO17727.1 - 1.1e-19 69.3 29.5 0.00016 21.6 1.3 4.3 4 0 0 4 4 4 4 Yeast mating factor alpha hormone DUF668 PF05003.7 EDO17728.1 - 0.36 11.0 5.6 0.41 10.8 0.5 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF668) RRM_1 PF00076.17 EDO17730.1 - 1.4e-10 40.5 0.2 3.5e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO17730.1 - 2.3e-07 30.7 0.1 4.8e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO17730.1 - 0.018 14.8 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.21 EDO17731.1 - 1.9e-05 24.6 0.2 7.7e-05 22.7 0.1 2.2 1 1 0 1 1 1 1 FHA domain PilZ PF07238.9 EDO17731.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 PilZ domain MPC PF03650.8 EDO17733.1 - 5.1e-44 149.0 0.2 6e-44 148.8 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Alg14 PF08660.6 EDO17733.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.4 1 1 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like TLD PF07534.11 EDO17734.1 - 8.7e-27 93.8 0.0 5.7e-26 91.1 0.0 2.1 1 1 0 1 1 1 1 TLD PAXIP1_C PF15364.1 EDO17734.1 - 0.0048 16.8 0.2 0.011 15.6 0.1 1.6 2 0 0 2 2 2 1 PAXIP1-associated-protein-1 C term PTIP binding protein DEAD PF00270.24 EDO17735.1 - 1.1e-49 168.2 1.3 3.1e-48 163.4 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO17735.1 - 5.9e-30 102.9 0.0 4.3e-28 96.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO17735.1 - 5.2e-06 26.4 9.8 1.3e-05 25.1 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EDO17735.1 - 0.0019 16.6 0.2 0.0019 16.6 0.1 3.6 3 2 0 3 3 3 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 EDO17735.1 - 0.0093 15.0 0.0 0.0093 15.0 0.0 2.8 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Prismane PF03063.15 EDO17735.1 - 1 7.6 6.1 0.34 9.2 2.2 1.6 2 0 0 2 2 2 0 Prismane/CO dehydrogenase family Vfa1 PF08432.5 EDO17735.1 - 1.8 8.5 27.2 3.9 7.4 18.8 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.1 EDO17735.1 - 4.9 6.8 14.7 11 5.7 10.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A AA_permease_2 PF13520.1 EDO17736.1 - 1.1e-50 172.4 44.7 1.4e-50 172.1 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EDO17736.1 - 8.2e-23 80.4 37.0 1.1e-22 80.0 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease Ribosomal_L30 PF00327.15 EDO17737.1 - 2.5e-19 68.5 0.9 5e-19 67.6 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 EDO17737.1 - 9.7e-14 51.1 6.8 1.7e-13 50.3 4.7 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DUF1771 PF08590.5 EDO17738.1 - 8.3e-18 64.1 4.3 1e-17 63.8 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) OstA_C PF04453.9 EDO17738.1 - 0.0065 15.5 0.8 0.0072 15.4 0.5 1.1 1 0 0 1 1 1 1 Organic solvent tolerance protein Dispanin PF04505.7 EDO17738.1 - 0.018 14.5 0.3 0.027 13.9 0.2 1.2 1 0 0 1 1 1 0 Interferon-induced transmembrane protein MRP-L46 PF11788.3 EDO17738.1 - 0.095 13.3 1.0 0.1 13.2 0.7 1.1 1 0 0 1 1 1 0 39S mitochondrial ribosomal protein L46 Seryl_tRNA_N PF02403.17 EDO17738.1 - 0.15 12.1 1.8 0.18 11.8 1.2 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3810 PF12725.2 EDO17739.1 - 0.04 12.8 0.5 0.18 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DUF1664 PF07889.7 EDO17739.1 - 0.19 11.4 1.1 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) IncA PF04156.9 EDO17739.1 - 1.1 8.8 4.4 2 7.9 3.0 1.4 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EDO17739.1 - 3.1 7.6 8.7 14 5.5 0.1 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding HSF_DNA-bind PF00447.12 EDO17740.1 - 5.5e-34 116.4 2.7 1.1e-33 115.5 1.9 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding AFT PF08731.6 EDO17742.1 - 4.3e-40 136.3 4.6 4.3e-40 136.3 3.2 3.2 2 2 0 2 2 2 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 EDO17742.1 - 4.3e-05 23.0 0.5 0.1 12.1 0.0 2.5 2 0 0 2 2 2 2 MuDR family transposase Zip PF02535.17 EDO17742.1 - 0.44 9.4 19.5 0.31 10.0 11.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter RNA_POL_M_15KD PF02150.11 EDO17743.1 - 3e-16 58.8 3.8 3e-16 58.8 2.7 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 EDO17743.1 - 7.8e-15 54.2 15.8 6.8e-14 51.2 1.9 3.1 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 EDO17743.1 - 0.0013 18.9 2.6 0.013 15.7 0.2 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar DUF2387 PF09526.5 EDO17743.1 - 0.0029 17.5 3.7 0.039 13.8 0.3 2.3 2 0 0 2 2 2 1 Probable metal-binding protein (DUF2387) Rubredoxin PF00301.15 EDO17743.1 - 0.019 14.8 4.3 28 4.6 0.1 4.0 4 0 0 4 4 4 0 Rubredoxin DZR PF12773.2 EDO17743.1 - 0.023 14.5 7.7 0.44 10.4 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-UBP PF02148.14 EDO17743.1 - 0.036 14.1 3.8 0.41 10.7 0.3 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Zn_Tnp_IS1595 PF12760.2 EDO17743.1 - 0.096 12.5 10.5 4.8 7.0 0.5 3.1 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Cytochrome_C7 PF14522.1 EDO17743.1 - 0.12 12.0 3.6 0.2 11.2 0.1 2.3 2 1 0 2 2 2 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 EDO17743.1 - 0.13 12.5 0.6 0.13 12.5 0.4 2.1 2 1 0 2 2 2 0 Cytochrome c3 C1_4 PF07975.7 EDO17743.1 - 0.18 11.8 10.8 0.78 9.7 0.6 3.0 2 1 1 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 EDO17743.1 - 0.21 11.5 9.9 5.3 7.0 0.2 4.0 4 0 0 4 4 4 0 Zinc ribbon domain DUF2296 PF10058.4 EDO17743.1 - 0.53 10.0 6.3 1.2 8.9 0.3 2.5 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) IBR PF01485.16 EDO17743.1 - 0.65 9.9 7.7 1.9 8.4 0.3 2.8 2 1 0 2 2 2 0 IBR domain zf-CHY PF05495.7 EDO17743.1 - 0.7 10.0 8.6 0.51 10.5 0.9 2.3 2 1 0 2 2 2 0 CHY zinc finger zf-CSL PF05207.8 EDO17743.1 - 1.3 8.6 4.8 6.9 6.2 0.2 2.4 2 0 0 2 2 2 0 CSL zinc finger Rpr2 PF04032.11 EDO17743.1 - 1.8 8.4 7.7 1.3e+02 2.5 5.4 2.6 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HypA PF01155.14 EDO17743.1 - 4.1 7.1 7.7 21 4.8 2.9 2.9 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 EDO17743.1 - 6.3 6.6 13.5 0.25 11.0 2.6 2.6 2 2 0 2 2 2 0 zinc-RING finger domain Pkinase PF00069.20 EDO17744.1 - 1.8e-72 243.5 0.2 8e-72 241.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17744.1 - 7.6e-40 136.6 0.0 1.1e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17744.1 - 2.4e-06 26.7 0.0 4.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO17744.1 - 0.051 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDO17744.1 - 0.054 12.3 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EDO17744.1 - 0.21 10.8 0.0 0.21 10.8 0.0 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 EDO17745.1 - 7.2e-30 103.9 0.0 2e-29 102.5 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17745.1 - 1.9e-10 40.2 0.0 4.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO17745.1 - 0.038 13.7 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family JAB PF01398.16 EDO17746.1 - 6e-34 116.2 0.3 6e-34 116.2 0.2 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EDO17746.1 - 1.2e-25 89.7 4.6 3.7e-25 88.2 3.2 1.8 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EDO17746.1 - 1.4e-08 34.2 0.0 2.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EDO17746.1 - 0.041 13.3 3.2 0.14 11.6 0.0 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) Peptidase_M24 PF00557.19 EDO17747.1 - 4.9e-58 196.1 0.0 6.2e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EDO17747.1 - 3.8e-27 94.3 0.1 2.2e-26 91.8 0.1 2.2 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.2 EDO17747.1 - 0.09 12.3 0.1 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) PGM_PMM_I PF02878.11 EDO17748.1 - 7.4e-34 116.1 0.1 1.1e-33 115.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EDO17748.1 - 2.1e-24 85.7 0.0 3.8e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EDO17748.1 - 3e-10 40.3 0.0 7.1e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EDO17748.1 - 1.4e-08 34.5 0.0 3.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain RRN3 PF05327.6 EDO17749.1 - 5.1e-190 632.3 12.3 5.9e-190 632.1 8.5 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 EDO17749.1 - 0.044 11.7 11.0 0.021 12.7 5.8 1.8 2 0 0 2 2 2 0 Nop14-like family DUF1539 PF07560.6 EDO17749.1 - 0.22 11.3 5.9 0.1 12.4 0.3 3.3 4 1 0 4 4 4 0 Domain of Unknown Function (DUF1539) BUD22 PF09073.5 EDO17749.1 - 0.24 10.4 7.6 0.45 9.5 5.3 1.3 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EDO17749.1 - 0.82 8.0 16.9 0.019 13.5 7.1 1.5 2 0 0 2 2 2 0 Daxx Family DUF4404 PF14357.1 EDO17749.1 - 4.1 7.8 7.2 4.2 7.8 3.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF2457 PF10446.4 EDO17749.1 - 9.3 4.8 13.7 15 4.2 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SRP9-21 PF05486.7 EDO17750.1 - 6.8e-22 77.0 0.6 6.8e-22 77.0 0.4 2.2 1 1 1 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Img2 PF05046.9 EDO17750.1 - 0.062 13.5 4.8 0.095 12.9 2.9 1.6 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) LAM_C PF12544.3 EDO17750.1 - 0.18 11.8 5.4 0.21 11.6 3.4 1.5 1 1 0 1 1 1 0 Lysine-2,3-aminomutase Rb_C PF08934.5 EDO17750.1 - 0.89 9.1 7.6 1.4 8.4 5.3 1.4 1 1 0 1 1 1 0 Rb C-terminal domain WD40 PF00400.27 EDO17751.1 - 9.2e-24 82.4 20.2 5.9e-08 32.3 0.3 7.1 8 0 0 8 8 8 4 WD domain, G-beta repeat Prenyltransf PF01255.14 EDO17752.1 - 1.3e-68 230.4 0.3 1.8e-68 229.9 0.2 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase zf-MYND PF01753.13 EDO17753.1 - 1.9e-07 30.7 18.8 4.6e-07 29.5 13.0 1.7 1 1 0 1 1 1 1 MYND finger Arm PF00514.18 EDO17753.1 - 0.059 13.2 0.0 10 6.1 0.0 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat CS PF04969.11 EDO17754.1 - 0.0019 18.7 0.5 0.0033 17.9 0.4 1.5 1 1 0 1 1 1 1 CS domain Aldose_epim PF01263.15 EDO17755.1 - 6e-48 163.4 0.3 7e-48 163.2 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Pkinase PF00069.20 EDO17756.1 - 1.2e-57 195.0 0.0 1.7e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17756.1 - 2.2e-23 82.6 0.0 1.3e-22 80.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17756.1 - 0.0089 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO17756.1 - 0.026 13.5 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AP_endonuc_2 PF01261.19 EDO17757.1 - 2.5e-32 111.8 0.0 3.4e-32 111.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel XPG_N PF00752.12 EDO17758.1 - 1.5e-39 134.2 0.0 2.8e-39 133.4 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EDO17758.1 - 5.6e-27 93.6 0.1 1.3e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EDO17758.1 - 7.9e-07 29.2 0.0 7.9e-07 29.2 0.0 2.5 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold DUF947 PF06102.7 EDO17758.1 - 0.00029 20.7 0.3 0.00029 20.7 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF947) HHH_5 PF14520.1 EDO17758.1 - 0.0037 17.4 0.0 0.023 14.8 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain Transposase_20 PF02371.11 EDO17758.1 - 0.017 15.2 0.1 0.25 11.4 0.0 2.4 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family HHH_2 PF12826.2 EDO17758.1 - 0.017 14.9 0.0 0.052 13.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2428 PF10350.4 EDO17760.1 - 3.7e-69 232.5 0.2 7.8e-69 231.5 0.1 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EDO17760.1 - 7.1e-06 25.6 0.2 0.84 9.8 0.0 6.1 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EDO17760.1 - 0.0076 16.5 0.0 0.46 10.8 0.0 3.4 3 0 0 3 3 3 1 HEAT repeats SAP30_Sin3_bdg PF13867.1 EDO17761.1 - 8.5e-15 54.3 0.1 1.6e-09 37.4 0.0 2.4 1 1 1 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF2521 PF10730.4 EDO17761.1 - 0.059 13.1 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2521) DNA_pol3_a_NII PF11490.3 EDO17761.1 - 0.095 12.3 0.9 0.38 10.3 0.4 2.0 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II DUF2410 PF10307.4 EDO17762.1 - 7.8e-69 231.0 4.9 1.2e-68 230.4 3.4 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) DUF3901 PF13040.1 EDO17762.1 - 0.0077 15.4 1.4 0.035 13.4 1.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3901) SRR1 PF07985.7 EDO17762.1 - 0.11 12.4 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 SRR1 Nup188 PF10487.4 EDO17763.1 - 3.2e-188 627.7 51.4 5.4e-188 626.9 35.6 1.3 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 RRN9 PF10680.4 EDO17764.1 - 7e-18 64.1 0.1 1.9e-17 62.7 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor Caveolin PF01146.12 EDO17764.1 - 0.12 11.9 0.1 0.29 10.6 0.1 1.6 1 0 0 1 1 1 0 Caveolin SRP19 PF01922.12 EDO17765.1 - 6.3e-29 100.4 0.0 1.3e-28 99.3 0.0 1.6 1 0 0 1 1 1 1 SRP19 protein Cyt-b5 PF00173.23 EDO17766.1 - 1.9e-12 46.7 0.8 2.3e-11 43.3 0.0 2.6 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EDO17766.1 - 3.5e-11 43.5 23.5 5.1e-11 42.9 13.9 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EDO17766.1 - 0.028 14.4 0.1 0.057 13.4 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Zds_C PF08632.5 EDO17767.1 - 4e-32 109.3 1.5 8.2e-32 108.3 1.0 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ubie_methyltran PF01209.13 EDO17768.1 - 7.2e-100 332.8 0.2 8.7e-100 332.6 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EDO17768.1 - 2.2e-13 50.0 0.0 3.3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO17768.1 - 1.3e-09 38.3 0.0 2.4e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO17768.1 - 2.4e-09 37.5 0.0 4.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO17768.1 - 1e-07 32.2 0.0 1.7e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO17768.1 - 3.8e-07 29.9 0.0 5.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO17768.1 - 6.6e-06 26.6 0.0 1.2e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FAM104 PF15434.1 EDO17768.1 - 0.0022 18.2 3.4 0.0041 17.3 2.4 1.4 1 0 0 1 1 1 1 Family 104 Methyltransf_26 PF13659.1 EDO17768.1 - 0.0025 17.8 0.0 0.0072 16.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EDO17768.1 - 0.0066 16.0 0.0 0.26 10.8 0.0 2.3 1 1 1 2 2 2 1 Hypothetical methyltransferase Methyltransf_28 PF02636.12 EDO17768.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 EDO17768.1 - 0.03 14.0 0.0 0.059 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain IL12p40_C PF10420.4 EDO17768.1 - 0.099 12.7 0.8 0.17 12.0 0.6 1.3 1 0 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus SR-25 PF10500.4 EDO17768.1 - 0.26 10.7 10.6 0.38 10.1 7.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 EDO17768.1 - 4.1 7.4 15.6 6.8 6.7 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Bul1_N PF04425.7 EDO17769.1 - 8.6e-164 545.2 5.4 8.6e-164 545.2 3.8 2.9 2 2 2 4 4 4 1 Bul1 N terminus Bul1_C PF04426.7 EDO17769.1 - 1.8e-115 384.8 14.8 1.8e-115 384.8 10.2 2.7 4 0 0 4 4 4 1 Bul1 C terminus LETM1 PF07766.8 EDO17769.1 - 0.17 10.8 5.7 0.029 13.4 0.5 2.0 2 0 0 2 2 2 0 LETM1-like protein Glutaredoxin2_C PF04399.8 EDO17769.1 - 0.43 10.1 6.2 0.07 12.7 0.3 2.5 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain CTK3_C PF12350.3 EDO17770.1 - 1.2e-21 76.4 3.1 1.2e-21 76.4 2.1 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.3 EDO17770.1 - 1.6e-07 31.0 1.2 0.01 15.4 0.0 2.8 3 0 0 3 3 3 2 CTD kinase subunit gamma CTK3 Anp1 PF03452.9 EDO17772.1 - 1.8e-126 420.8 0.0 2.4e-126 420.4 0.0 1.1 1 0 0 1 1 1 1 Anp1 MFS_1 PF07690.11 EDO17773.1 - 1.2e-38 132.7 50.6 1.8e-37 128.8 35.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.6 EDO17773.1 - 0.0043 16.7 20.8 0.0043 16.7 14.4 3.9 2 1 1 4 4 4 1 7TM diverse intracellular signalling Sugar_tr PF00083.19 EDO17773.1 - 0.44 9.0 34.8 0.0039 15.8 7.8 3.2 1 1 1 3 3 3 0 Sugar (and other) transporter Pyr_redox_2 PF07992.9 EDO17774.1 - 9.7e-29 100.6 1.6 2.4e-19 69.9 0.0 3.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO17774.1 - 8.5e-12 45.3 0.1 2.3e-09 37.5 0.2 3.0 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO17774.1 - 1.7e-10 41.3 0.2 0.00012 22.2 0.0 3.3 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Cut8_C PF08559.5 EDO17774.1 - 0.067 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Cut8 six-helix bundle Gtr1_RagA PF04670.7 EDO17775.1 - 9.8e-92 306.2 4.4 1.4e-91 305.7 3.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EDO17775.1 - 2e-09 37.0 0.5 7.4e-09 35.2 0.1 2.0 2 0 0 2 2 2 1 Ras family Arf PF00025.16 EDO17775.1 - 7.2e-08 31.8 1.0 1.1e-07 31.2 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EDO17775.1 - 7.3e-08 32.9 0.3 2.2e-07 31.3 0.1 2.0 2 1 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EDO17775.1 - 2.7e-06 27.3 0.0 8.8e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Runt PF00853.14 EDO17775.1 - 0.00096 18.6 1.3 0.038 13.4 0.1 2.5 2 0 0 2 2 2 1 Runt domain ABC_tran PF00005.22 EDO17775.1 - 0.0014 18.9 0.8 0.024 14.9 0.1 2.4 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EDO17775.1 - 0.0086 15.5 0.4 0.026 14.0 0.2 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain Fer2_3 PF13085.1 EDO17775.1 - 0.038 13.8 1.5 8.5 6.2 0.1 2.4 1 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DUF815 PF05673.8 EDO17775.1 - 0.04 12.8 0.0 0.089 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Guanylate_kin PF00625.16 EDO17775.1 - 0.042 13.2 5.9 0.13 11.6 0.5 3.2 3 1 0 3 3 3 0 Guanylate kinase AAA_10 PF12846.2 EDO17775.1 - 0.05 13.0 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA-like domain DUF3219 PF11514.3 EDO17775.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3219) ThylakoidFormat PF11264.3 EDO17775.1 - 0.9 9.1 5.9 4.8 6.7 0.1 3.0 2 1 1 3 3 3 0 Thylakoid formation protein SQS_PSY PF00494.14 EDO17776.1 - 6.7e-40 137.0 0.0 8.3e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF3258 PF11646.3 EDO17776.1 - 0.045 13.9 0.1 0.37 10.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF3258 TFIIA_gamma_N PF02268.11 EDO17776.1 - 0.083 12.4 0.3 0.19 11.3 0.2 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain Sugar_tr PF00083.19 EDO17777.1 - 2.5e-40 138.4 17.6 3.3e-40 138.0 12.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO17777.1 - 2.6e-26 92.2 26.3 1.7e-21 76.3 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BRI3BP PF14965.1 EDO17777.1 - 0.00097 18.5 0.6 0.0025 17.1 0.4 1.7 1 0 0 1 1 1 1 Negative regulator of p53/TP53 Bax1-I PF01027.15 EDO17777.1 - 1.5 8.3 22.9 0.66 9.5 5.4 2.7 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Tubulin PF00091.20 EDO17778.1 - 3e-71 239.6 0.0 4.2e-71 239.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EDO17778.1 - 8.8e-50 167.9 0.4 1.4e-49 167.3 0.3 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain MSP PF01716.13 EDO17778.1 - 0.028 13.4 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide HMG_CoA_synt_C PF08540.5 EDO17779.1 - 1.1e-104 349.9 3.6 1.3e-104 349.6 2.5 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EDO17779.1 - 2.9e-92 306.9 0.2 4.1e-92 306.4 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal RPM2 PF08579.6 EDO17780.1 - 1.1e-38 132.0 6.5 1.1e-38 132.0 4.5 6.0 6 1 0 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) Ish1 PF10281.4 EDO17782.1 - 1.3e-35 121.1 26.7 3.4e-11 42.9 1.0 6.6 7 0 0 7 7 7 5 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EDO17782.1 - 0.0012 18.3 0.0 0.64 9.5 0.0 3.6 4 0 0 4 4 4 1 SAP domain SHQ1 PF04925.10 EDO17782.1 - 0.0051 16.2 0.7 0.011 15.2 0.5 1.5 1 0 0 1 1 1 1 SHQ1 protein Slx4 PF09494.5 EDO17782.1 - 0.0071 16.0 0.6 12 5.7 0.0 4.4 4 0 0 4 4 4 1 Slx4 endonuclease CAMSAP_CKK PF08683.6 EDO17782.1 - 0.031 13.9 0.1 0.072 12.7 0.1 1.6 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated Isochorismatase PF00857.15 EDO17782.1 - 0.14 12.0 0.7 26 4.6 0.0 2.9 2 1 1 3 3 3 0 Isochorismatase family Mst1_SARAH PF11629.3 EDO17782.1 - 0.18 11.6 4.9 4.4 7.1 0.0 4.0 4 0 0 4 4 4 0 C terminal SARAH domain of Mst1 Ish1 PF10281.4 EDO17783.1 - 1.7e-24 85.5 29.8 1.6e-08 34.4 0.6 7.1 8 0 0 8 8 8 5 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EDO17783.1 - 0.0047 16.4 0.5 0.17 11.4 0.0 3.6 4 0 0 4 4 4 1 HeH/LEM domain Herpes_ori_bp PF02399.10 EDO17783.1 - 0.022 12.7 2.1 1.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Origin of replication binding protein ALMT PF11744.3 EDO17783.1 - 0.033 12.8 3.5 0.11 11.1 0.1 2.6 2 1 1 3 3 3 0 Aluminium activated malate transporter Gal4_dimer PF03902.8 EDO17783.1 - 0.13 12.1 0.5 0.58 10.1 0.0 2.4 2 0 0 2 2 2 0 Gal4-like dimerisation domain ApoLp-III PF07464.6 EDO17783.1 - 3.9 7.4 8.7 0.92 9.5 0.3 3.5 4 0 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) Ribosomal_S25 PF03297.10 EDO17786.1 - 9.1e-44 147.8 6.8 1e-43 147.6 4.7 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 EDO17786.1 - 0.00067 19.3 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.6 EDO17786.1 - 0.021 14.1 0.3 0.03 13.6 0.2 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_DeoR PF08220.7 EDO17786.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TAF4 PF05236.9 EDO17786.1 - 0.078 12.2 1.1 0.11 11.8 0.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Copper-fist PF00649.13 EDO17787.1 - 1.2e-22 78.7 1.2 2.2e-22 77.9 0.8 1.4 1 0 0 1 1 1 1 Copper fist DNA binding domain SNF2_N PF00176.18 EDO17788.1 - 3.6e-67 226.2 0.0 5.4e-67 225.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EDO17788.1 - 1.7e-51 174.8 5.0 1.7e-51 174.8 3.5 2.9 3 0 0 3 3 3 1 Rad54 N terminal Helicase_C PF00271.26 EDO17788.1 - 3.2e-13 49.3 0.0 7e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EDO17788.1 - 4.4e-08 32.2 0.0 4.4e-08 32.2 0.0 3.4 3 1 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EDO17788.1 - 0.00012 21.6 0.0 0.00024 20.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dCMP_cyt_deam_1 PF00383.17 EDO17789.1 - 1.4e-14 53.5 0.2 1.9e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EDO17789.1 - 1.7e-09 37.7 0.0 2.7e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EDO17789.1 - 3.2e-06 26.6 0.4 0.0022 17.4 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Ribosomal_S14 PF00253.16 EDO17789.1 - 0.0051 16.1 1.1 0.021 14.1 0.0 2.2 2 1 0 2 2 2 1 Ribosomal protein S14p/S29e Zn_clus PF00172.13 EDO17790.1 - 0.00028 20.7 6.4 0.0019 18.0 0.9 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain YABBY PF04690.8 EDO17790.1 - 0.082 13.1 2.8 0.23 11.7 0.3 2.5 1 1 2 3 3 3 0 YABBY protein Sua5_yciO_yrdC PF01300.13 EDO17792.1 - 2e-47 160.7 0.0 3.5e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EDO17792.1 - 2.8e-31 108.2 0.0 4.4e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding E1-E2_ATPase PF00122.15 EDO17793.1 - 6.7e-79 264.1 0.2 1.3e-78 263.2 0.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EDO17793.1 - 2.6e-47 160.6 3.0 2.6e-47 160.6 2.1 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EDO17793.1 - 1.9e-34 120.0 0.1 3.3e-34 119.1 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EDO17793.1 - 1.9e-18 66.2 0.2 4.1e-18 65.1 0.1 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EDO17793.1 - 1.8e-17 64.1 0.0 4.1e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EDO17793.1 - 6.9e-14 51.0 0.0 1.6e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EDO17793.1 - 0.0016 18.0 0.8 0.0016 18.0 0.5 2.9 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase RNA_pol_Rpb2_6 PF00562.23 EDO17794.1 - 2.3e-115 385.4 0.0 3.6e-115 384.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EDO17794.1 - 9.7e-47 158.5 0.1 1.4e-46 157.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EDO17794.1 - 3.6e-37 127.6 0.0 7.8e-37 126.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EDO17794.1 - 3.8e-25 87.4 0.1 5.7e-24 83.6 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EDO17794.1 - 3.1e-23 81.4 0.0 6.5e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EDO17794.1 - 1.9e-15 56.8 0.0 2.2e-14 53.4 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EDO17794.1 - 4.5e-05 23.3 0.1 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 B12D PF06522.6 EDO17795.1 - 0.0062 16.2 0.0 0.0079 15.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Mito_carr PF00153.22 EDO17796.1 - 2.8e-69 228.8 0.4 8.9e-23 79.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3792 PF12670.2 EDO17796.1 - 0.036 13.9 3.5 2.2 8.1 0.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3792) zf-C2H2 PF00096.21 EDO17797.1 - 7.8e-09 35.3 10.9 0.00012 22.2 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO17797.1 - 9.5e-06 25.6 0.3 9.5e-06 25.6 0.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO17797.1 - 0.0003 20.9 10.1 0.022 15.0 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EDO17797.1 - 0.0097 16.0 1.6 0.0097 16.0 1.1 3.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDO17797.1 - 0.12 12.5 5.3 1.5 9.1 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Fer4_16 PF13484.1 EDO17797.1 - 0.53 11.0 0.1 0.53 11.0 0.1 2.6 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain zf-H2C2_5 PF13909.1 EDO17797.1 - 0.64 10.3 9.5 3.9 7.9 0.6 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.10 EDO17797.1 - 2.3 8.0 12.5 3.3 7.5 4.3 2.9 1 1 1 2 2 2 0 BED zinc finger Macoilin PF09726.4 EDO17797.1 - 6.3 4.9 21.9 7.2 4.7 15.1 1.2 1 0 0 1 1 1 0 Transmembrane protein XRN_N PF03159.13 EDO17798.1 - 3.7e-100 334.1 0.4 3.7e-100 334.1 0.2 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Bud13 PF09736.4 EDO17799.1 - 3e-29 102.1 11.1 3e-29 102.1 7.7 2.8 2 2 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF4409 PF14365.1 EDO17799.1 - 0.011 15.9 3.8 0.013 15.6 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4409) MMR1 PF08505.5 EDO17799.1 - 6.8 6.6 16.8 1.3 8.9 3.9 2.2 1 1 1 2 2 2 0 Mitochondrial Myo2 receptor-related protein DUF4555 PF15093.1 EDO17800.1 - 0.016 14.1 0.4 0.024 13.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4555) DUF1748 PF08520.5 EDO17801.1 - 0.11 12.1 0.2 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1748) PUF PF00806.14 EDO17802.1 - 3.3e-50 164.8 29.1 1.6e-06 27.2 0.3 8.8 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Ribosomal_S8e PF01201.17 EDO17803.1 - 8.7e-41 139.1 7.9 4.7e-40 136.7 5.5 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.7 EDO17803.1 - 0.05 13.2 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Homeo-prospero domain YebF PF13995.1 EDO17803.1 - 0.065 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 YebF-like protein AAA_13 PF13166.1 EDO17803.1 - 0.078 11.4 6.1 0.099 11.0 4.2 1.0 1 0 0 1 1 1 0 AAA domain DUF3959 PF13105.1 EDO17803.1 - 7.1 5.8 9.1 3.6 6.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Sas10_Utp3 PF04000.10 EDO17804.1 - 5.2e-14 52.1 1.8 5.2e-14 52.1 1.2 2.4 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Syntaxin_2 PF14523.1 EDO17804.1 - 0.03 14.3 3.4 4.6 7.3 2.4 2.9 1 1 0 1 1 1 0 Syntaxin-like protein Hid1 PF12722.2 EDO17804.1 - 2 5.9 11.5 3.3 5.2 8.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NOA36 PF06524.7 EDO17804.1 - 9.7 5.3 10.3 23 4.1 7.2 1.6 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.5 EDO17805.1 - 8.5e-48 162.7 12.9 9.6e-48 162.6 9.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SprA-related PF12118.3 EDO17805.1 - 0.0074 15.6 6.2 0.009 15.3 4.3 1.1 1 0 0 1 1 1 1 SprA-related family GLTSCR1 PF15249.1 EDO17805.1 - 0.022 14.8 8.3 0.041 13.9 5.7 1.5 1 0 0 1 1 1 0 Glioma tumor suppressor candidate region DUF664 PF04978.7 EDO17805.1 - 0.1 12.8 0.6 0.17 12.1 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF664) TIP120 PF08623.5 EDO17805.1 - 0.54 9.8 7.3 0.27 10.8 2.8 1.9 1 1 1 2 2 2 0 TATA-binding protein interacting (TIP20) Exonuc_VII_L PF02601.10 EDO17805.1 - 0.68 9.0 13.6 0.88 8.7 9.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DDHD PF02862.12 EDO17805.1 - 1.3 8.7 9.3 2 8.1 6.4 1.3 1 0 0 1 1 1 0 DDHD domain Prenyltransf PF01255.14 EDO17805.1 - 2.6 7.1 7.9 0.5 9.4 2.9 1.6 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase VSG_B PF13206.1 EDO17805.1 - 2.7 7.0 12.2 3.5 6.6 8.4 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF342 PF03961.8 EDO17805.1 - 4.2 5.6 12.1 5.5 5.2 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF334 PF03904.8 EDO17805.1 - 4.3 6.6 10.7 6.3 6.0 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) V_ATPase_I PF01496.14 EDO17805.1 - 9 4.0 11.7 11 3.7 8.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3543 PF12063.3 EDO17806.1 - 2.3e-64 216.8 6.9 2.3e-64 216.8 4.8 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EDO17806.1 - 1.3e-58 198.2 0.2 5.8e-58 196.0 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17806.1 - 1.7e-42 145.3 0.0 3.9e-42 144.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase ArfGap PF01412.13 EDO17807.1 - 5.6e-30 103.5 0.0 5.6e-30 103.5 0.0 3.0 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf PAT1 PF09770.4 EDO17807.1 - 0.002 16.4 55.2 0.0022 16.3 38.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EDO17807.1 - 0.0048 15.1 82.4 0.0062 14.8 57.1 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Mnd1 PF03962.10 EDO17808.1 - 3.1e-43 147.6 9.7 3.5e-43 147.4 6.7 1.0 1 0 0 1 1 1 1 Mnd1 family DUF2408 PF10303.4 EDO17808.1 - 0.0071 16.4 6.3 0.53 10.4 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2408) PsbU PF06514.6 EDO17808.1 - 0.076 12.8 0.5 0.18 11.6 0.3 1.7 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) Swi5 PF07061.6 EDO17808.1 - 0.99 9.2 6.5 0.52 10.1 0.1 2.9 2 1 1 3 3 3 0 Swi5 Syntaxin PF00804.20 EDO17808.1 - 1.7 8.8 9.5 5.2 7.2 6.6 2.0 1 1 0 1 1 1 0 Syntaxin DUF972 PF06156.8 EDO17808.1 - 5.5 7.3 8.7 1 9.7 1.5 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) 2-Hacid_dh_C PF02826.14 EDO17809.1 - 1.4e-30 105.7 0.0 2.3e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDO17809.1 - 8.5e-07 28.5 0.0 1.2e-05 24.7 0.0 2.4 2 1 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Transp_cyt_pur PF02133.10 EDO17810.1 - 4.5e-16 58.4 24.2 4.5e-16 58.4 16.8 1.8 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Nramp PF01566.13 EDO17810.1 - 0.8 8.4 21.2 0.88 8.2 7.2 2.4 2 0 0 2 2 2 0 Natural resistance-associated macrophage protein Macro_2 PF14519.1 EDO17812.1 - 8.8e-149 494.1 0.1 9.8e-149 494.0 0.1 1.0 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.16 EDO17812.1 - 0.0085 15.9 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 Macro domain Ribophorin_II PF05817.9 EDO17813.1 - 1.5e-09 36.6 0.6 2.2e-09 36.1 0.4 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II ETRAMP PF09716.5 EDO17813.1 - 0.029 14.3 0.5 0.029 14.3 0.3 3.1 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Peptidase_S24 PF00717.18 EDO17814.1 - 1.1e-05 25.0 0.0 5.8e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 EDO17814.1 - 0.0019 17.7 0.0 0.0058 16.1 0.0 1.8 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 adh_short PF00106.20 EDO17815.1 - 0.009 15.9 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase LUC7 PF03194.10 EDO17816.1 - 2.3e-68 230.5 5.5 2.7e-68 230.2 3.8 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Cloacin PF03515.9 EDO17816.1 - 0.078 12.1 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Colicin-like bacteriocin tRNase domain Seryl_tRNA_N PF02403.17 EDO17816.1 - 2.5 8.1 8.4 0.8 9.7 0.2 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Nup35_RRM PF05172.8 EDO17817.1 - 2.2e-36 123.6 0.0 4.9e-36 122.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EDO17817.1 - 0.0065 16.2 0.0 0.021 14.5 0.0 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Prenyltrans PF00432.16 EDO17818.1 - 2.6e-45 151.6 11.3 5.6e-14 51.4 0.1 6.6 6 1 1 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDO17818.1 - 1.6e-23 83.2 0.0 1.8e-15 57.3 0.0 3.5 2 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDO17818.1 - 0.00021 21.2 0.0 0.0025 17.7 0.0 2.6 2 1 1 3 3 3 2 Prenyltransferase-like Crl PF07417.7 EDO17818.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator Crl Pec_lyase PF09492.5 EDO17818.1 - 0.089 11.9 1.2 5.3 6.1 0.0 2.9 2 1 1 3 3 3 0 Pectic acid lyase A2M_comp PF07678.9 EDO17818.1 - 0.15 11.2 0.8 18 4.4 0.0 2.7 2 1 0 3 3 3 0 A-macroglobulin complement component DUF1014 PF06244.7 EDO17818.1 - 0.52 10.5 5.0 0.9 9.7 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) GCIP PF13324.1 EDO17818.1 - 2.1 7.4 5.7 3.9 6.6 2.9 1.9 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting SRP14 PF02290.10 EDO17819.1 - 1.1e-28 98.9 0.2 1.8e-28 98.2 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle 14kD protein DUF4159 PF13709.1 EDO17819.1 - 0.048 12.7 0.0 0.056 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) MFS_1 PF07690.11 EDO17820.1 - 2.6e-13 49.4 17.2 7.1e-13 47.9 11.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EDO17820.1 - 2.7e-12 46.4 5.9 2.7e-12 46.4 4.1 1.8 2 0 0 2 2 2 1 Nodulin-like PMT PF02366.13 EDO17821.1 - 2.1e-78 263.0 23.2 2.1e-78 263.0 16.1 2.1 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDO17821.1 - 1.2e-50 171.7 0.4 2.1e-50 170.9 0.3 1.4 1 0 0 1 1 1 1 MIR domain DUF952 PF06108.7 EDO17822.1 - 0.051 13.4 0.0 0.085 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF952) Ribosomal_S8 PF00410.14 EDO17823.1 - 2.2e-21 76.0 0.0 2.6e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 ATG16 PF08614.6 EDO17824.1 - 1.2e-25 90.4 16.5 5.2e-23 81.8 9.9 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DNA_gyraseB PF00204.20 EDO17824.1 - 0.019 14.2 0.4 0.027 13.6 0.3 1.2 1 0 0 1 1 1 0 DNA gyrase B Herpes_BLRF2 PF05812.7 EDO17824.1 - 0.027 14.2 2.7 0.05 13.4 1.9 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DivIVA PF05103.8 EDO17824.1 - 0.028 14.4 3.2 0.046 13.7 2.2 1.4 1 0 0 1 1 1 0 DivIVA protein Fez1 PF06818.10 EDO17824.1 - 0.029 14.4 4.0 0.035 14.1 2.7 1.1 1 0 0 1 1 1 0 Fez1 DUF3166 PF11365.3 EDO17824.1 - 0.3 11.5 4.2 0.35 11.3 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) KLRAQ PF10205.4 EDO17824.1 - 0.94 9.5 5.1 1.8 8.6 3.5 1.5 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF972 PF06156.8 EDO17824.1 - 1.2 9.5 5.8 1.4 9.2 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EDO17824.1 - 1.3 8.5 7.0 1.4 8.4 4.9 1.1 1 0 0 1 1 1 0 IncA protein bZIP_2 PF07716.10 EDO17824.1 - 3.6 7.4 8.1 0.89 9.4 2.1 2.7 2 1 1 3 3 3 0 Basic region leucine zipper UDPGP PF01704.13 EDO17826.1 - 2.1e-47 161.5 0.0 2.8e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EDO17826.1 - 0.095 12.7 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain Vezatin PF12632.2 EDO17827.1 - 2.7e-35 121.6 24.4 4.6e-35 120.9 16.9 1.4 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes LisH PF08513.6 EDO17828.1 - 2.8e-05 23.7 1.5 5.8e-05 22.6 1.0 1.6 1 0 0 1 1 1 1 LisH LNS2 PF08235.8 EDO17829.1 - 1.6e-70 235.7 0.1 8.4e-70 233.3 0.0 2.0 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EDO17829.1 - 1.4e-43 147.0 0.0 4.5e-43 145.4 0.0 1.9 1 0 0 1 1 1 1 lipin, N-terminal conserved region Mito_carr PF00153.22 EDO17830.1 - 3.6e-67 222.1 2.8 2e-22 78.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M22 PF00814.20 EDO17831.1 - 3e-69 233.5 0.0 3.8e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DNA_mis_repair PF01119.14 EDO17832.1 - 1.1e-27 95.9 3.1 3.6e-27 94.1 0.2 2.8 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EDO17832.1 - 4.6e-13 48.9 0.1 4.6e-13 48.9 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO17832.1 - 3.2e-09 36.4 0.1 1.2e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAGA_bind PF06217.7 EDO17832.1 - 1.8 8.4 5.9 2.9 7.7 4.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Zn_clus PF00172.13 EDO17833.1 - 1.5e-06 27.9 8.3 2.6e-06 27.2 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox PF00046.24 EDO17834.1 - 1.6e-16 59.6 2.4 2.9e-16 58.8 1.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EDO17834.1 - 0.0047 16.6 0.1 0.012 15.2 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain SPRY PF00622.23 EDO17835.1 - 6.6e-14 52.0 0.1 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 SPRY domain RINT1_TIP1 PF04437.8 EDO17836.1 - 5.4e-122 407.8 29.2 7.8e-122 407.3 20.2 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family SpoU_methylase PF00588.14 EDO17837.1 - 5.4e-27 94.4 0.0 2.2e-26 92.3 0.0 2.1 2 0 0 2 2 2 1 SpoU rRNA Methylase family PX PF00787.19 EDO17838.1 - 1.3e-23 82.8 0.3 1.5e-22 79.5 0.0 2.4 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EDO17838.1 - 2.9e-10 39.8 16.1 2.5e-07 30.1 0.7 2.5 2 0 0 2 2 2 2 Vps5 C terminal like Nup84_Nup100 PF04121.8 EDO17839.1 - 1.7e-240 799.4 21.2 2e-240 799.2 14.7 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF1512 PF07431.7 EDO17839.1 - 0.044 12.5 0.0 0.53 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) Chorismate_synt PF01264.16 EDO17840.1 - 1.2e-134 448.1 0.0 1.4e-134 447.9 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase GrpE PF01025.14 EDO17840.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 GrpE ACPS PF01648.15 EDO17841.1 - 1.1e-13 50.9 0.0 2e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Mito_carr PF00153.22 EDO17842.1 - 2.8e-57 190.4 3.1 4.7e-21 74.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Frataxin_Cyay PF01491.11 EDO17843.1 - 1.3e-33 115.0 0.0 1.7e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain RRM_1 PF00076.17 EDO17844.1 - 8.5e-53 175.8 1.9 2.1e-18 65.7 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO17844.1 - 4.8e-33 112.9 0.7 1.6e-11 43.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO17844.1 - 4.4e-29 100.1 0.7 1.1e-10 41.2 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO17844.1 - 0.002 17.8 0.1 0.067 12.9 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF3421 PF11901.3 EDO17844.1 - 0.022 14.5 0.1 3.3 7.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3421) Sds3 PF08598.6 EDO17845.1 - 8.2e-68 227.9 23.9 1.2e-66 224.2 16.5 2.0 1 1 0 1 1 1 1 Sds3-like Menin PF05053.8 EDO17845.1 - 0.029 12.5 8.4 0.046 11.8 5.8 1.3 1 0 0 1 1 1 0 Menin DUF484 PF04340.7 EDO17845.1 - 0.05 13.0 2.7 0.089 12.2 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF484 DUF2201_N PF13203.1 EDO17845.1 - 0.86 8.7 7.0 1.8 7.6 4.9 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4613 PF15390.1 EDO17845.1 - 1.6 6.7 8.1 2.4 6.2 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Neur_chan_memb PF02932.11 EDO17845.1 - 2.6 7.8 5.1 0.67 9.7 1.3 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Histone PF00125.19 EDO17846.1 - 2.5e-15 56.3 0.2 3.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDO17846.1 - 3.2e-05 23.8 0.1 5.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EDO17846.1 - 4.4e-05 23.3 0.2 6.2e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EDO17846.1 - 5e-05 23.3 0.1 7e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EDO17846.1 - 0.0012 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EDO17846.1 - 0.0042 16.7 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EDO17846.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 EDO17846.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EDO17847.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDO17847.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDO17847.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EDO17847.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF2416 PF10315.4 EDO17848.1 - 9.1e-42 141.6 0.3 1.1e-41 141.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) Tau95 PF09734.4 EDO17849.1 - 1.9e-63 214.6 1.8 1.9e-63 214.6 1.2 1.6 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit SSP160 PF06933.6 EDO17849.1 - 2 6.2 5.2 2.9 5.7 3.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PP2C PF00481.16 EDO17850.1 - 2.3e-65 220.4 0.8 3e-60 203.7 0.3 2.5 1 1 1 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EDO17850.1 - 0.016 14.9 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EDO17850.1 - 0.026 13.9 0.0 0.19 11.1 0.0 2.1 1 1 0 1 1 1 0 Protein phosphatase 2C Glyco_transf_20 PF00982.16 EDO17851.1 - 4.4e-202 671.7 0.1 5e-202 671.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EDO17851.1 - 0.0012 18.4 0.4 0.0026 17.2 0.1 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EDO17851.1 - 0.0013 18.2 0.8 0.42 10.0 0.1 3.1 2 1 0 2 2 2 2 Glycosyl transferases group 1 RNB PF00773.14 EDO17852.1 - 1.4e-92 310.4 0.0 2.4e-92 309.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EDO17852.1 - 3.4e-13 49.8 0.5 7.5e-13 48.7 0.4 1.6 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 EDO17852.1 - 0.016 14.6 0.0 0.045 13.2 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease B OB domain GAGA_bind PF06217.7 EDO17852.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family ABC_tran PF00005.22 EDO17853.1 - 2.8e-47 160.4 1.6 2.3e-22 79.7 0.0 3.4 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EDO17853.1 - 3.7e-19 68.3 11.0 3.7e-19 68.3 7.6 3.0 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 EDO17853.1 - 5.1e-17 62.7 15.8 7.2e-06 26.1 0.0 5.7 3 2 2 5 5 5 3 AAA domain SMC_N PF02463.14 EDO17853.1 - 5.2e-10 38.9 0.1 0.0042 16.3 0.1 3.6 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EDO17853.1 - 4.9e-09 37.0 2.2 0.00025 21.8 0.0 3.4 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.1 EDO17853.1 - 1.7e-07 31.3 0.4 0.0096 15.9 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EDO17853.1 - 1e-06 28.0 0.0 0.03 13.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 EDO17853.1 - 1.1e-06 28.4 0.0 0.0078 15.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 EDO17853.1 - 1.1e-06 28.6 1.8 0.05 13.5 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EDO17853.1 - 2.4e-06 27.7 0.7 0.17 12.0 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EDO17853.1 - 4.7e-06 27.0 29.3 0.43 10.8 0.0 5.2 5 0 0 5 5 5 2 AAA domain Miro PF08477.8 EDO17853.1 - 4.9e-06 27.0 0.0 0.17 12.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_14 PF13173.1 EDO17853.1 - 6.2e-06 26.1 0.6 0.2 11.5 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA PF00004.24 EDO17853.1 - 8.3e-06 26.0 0.2 0.079 13.1 0.0 3.5 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EDO17853.1 - 9.6e-06 25.5 0.0 0.13 12.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EDO17853.1 - 1.6e-05 24.3 4.4 0.069 12.6 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 EDO17853.1 - 1.8e-05 24.3 0.0 0.0091 15.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 EDO17853.1 - 5e-05 23.1 0.0 0.14 12.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.4 EDO17853.1 - 5.9e-05 22.5 2.0 0.12 11.8 0.0 3.5 4 0 0 4 4 3 2 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 EDO17853.1 - 8.3e-05 22.4 0.1 0.79 9.6 0.0 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EDO17853.1 - 9.1e-05 22.1 0.3 0.45 10.2 0.0 3.3 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EDO17853.1 - 0.00018 21.3 0.5 0.13 12.0 0.0 3.7 3 0 0 3 3 3 1 Dynamin family RNA_helicase PF00910.17 EDO17853.1 - 0.00047 20.2 2.3 0.85 9.8 0.0 3.8 4 0 0 4 4 3 1 RNA helicase AAA_10 PF12846.2 EDO17853.1 - 0.00089 18.7 1.9 1.5 8.1 0.0 3.7 3 1 0 3 3 3 1 AAA-like domain NB-ARC PF00931.17 EDO17853.1 - 0.00097 18.0 0.3 1.2 7.8 0.0 2.7 2 1 0 2 2 2 2 NB-ARC domain AAA_5 PF07728.9 EDO17853.1 - 0.0013 18.4 0.2 2 8.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDO17853.1 - 0.0022 18.3 12.8 0.19 12.0 1.0 4.3 4 2 0 4 4 4 2 AAA domain AAA_15 PF13175.1 EDO17853.1 - 0.0028 16.7 25.1 0.094 11.7 0.0 6.1 2 1 4 6 6 6 2 AAA ATPase domain AAA_25 PF13481.1 EDO17853.1 - 0.0048 16.3 0.0 3.5 6.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EDO17853.1 - 0.007 15.1 0.5 1.2 7.8 0.0 3.2 2 1 0 3 3 3 1 ArgK protein NTPase_1 PF03266.10 EDO17853.1 - 0.0079 15.9 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 1 NTPase cobW PF02492.14 EDO17853.1 - 0.01 15.2 0.0 1.6 8.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 EDO17853.1 - 0.015 14.6 1.2 0.17 11.1 0.0 2.6 3 0 0 3 3 3 0 Poxvirus A32 protein T2SE PF00437.15 EDO17853.1 - 0.02 13.8 0.0 0.3 9.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.13 EDO17853.1 - 0.022 14.0 0.0 5.1 6.3 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 EDO17853.1 - 0.027 14.1 12.6 0.051 13.2 0.0 3.3 4 0 0 4 4 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EDO17853.1 - 0.029 13.8 0.4 1.8 7.9 0.0 2.9 3 0 0 3 3 2 0 FtsK/SpoIIIE family SRP54 PF00448.17 EDO17853.1 - 0.033 13.6 0.0 2 7.8 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ras PF00071.17 EDO17853.1 - 0.091 12.1 1.6 7.6 5.9 0.0 3.3 4 0 0 4 4 4 0 Ras family DUF87 PF01935.12 EDO17853.1 - 1.2 8.9 0.0 1.2 8.9 0.0 5.0 5 1 1 6 6 6 0 Domain of unknown function DUF87 PRELI PF04707.9 EDO17854.1 - 7.3e-57 191.3 0.2 1.1e-56 190.7 0.1 1.3 1 0 0 1 1 1 1 PRELI-like family CBM49 PF09478.5 EDO17854.1 - 0.0031 17.5 0.6 0.0099 15.9 0.2 2.0 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 Bunya_RdRp PF04196.7 EDO17854.1 - 0.0058 14.7 0.6 0.006 14.6 0.4 1.1 1 0 0 1 1 1 1 Bunyavirus RNA dependent RNA polymerase DUF3829 PF12889.2 EDO17854.1 - 0.062 12.4 0.3 0.079 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) PrgI PF12666.2 EDO17856.1 - 0.033 14.3 0.8 0.048 13.8 0.6 1.2 1 0 0 1 1 1 0 PrgI family protein Peptidase_M24 PF00557.19 EDO17857.1 - 5.7e-49 166.5 0.1 7.6e-49 166.0 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 ATP-cone PF03477.11 EDO17857.1 - 0.032 14.6 0.1 8.2 6.9 0.0 2.3 2 0 0 2 2 2 0 ATP cone domain Cpn60_TCP1 PF00118.19 EDO17858.1 - 4.3e-143 477.4 3.4 4.9e-143 477.2 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-CCCH PF00642.19 EDO17859.1 - 1.3e-07 31.1 2.0 3.2e-07 29.8 1.4 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Arv1 PF04161.8 EDO17860.1 - 2.9e-78 262.5 10.7 4.5e-78 261.9 7.4 1.3 1 0 0 1 1 1 1 Arv1-like family PI3Ka PF00613.15 EDO17861.1 - 2.9e-70 235.2 3.4 4.9e-70 234.4 2.4 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EDO17861.1 - 1.2e-48 165.6 0.1 2.1e-47 161.5 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EDO17861.1 - 1.3e-19 70.4 0.2 3.6e-19 68.9 0.1 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 AMMECR1 PF01871.12 EDO17862.1 - 1.8e-34 118.3 0.0 2.6e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 adh_short PF00106.20 EDO17863.1 - 8.1e-33 113.6 0.0 1e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO17863.1 - 7.3e-14 52.1 0.1 9.3e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO17863.1 - 3.5e-11 43.1 0.0 4.6e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EDO17863.1 - 4.4e-05 23.1 0.2 0.0001 22.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EDO17863.1 - 0.0015 17.7 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EDO17863.1 - 0.007 15.8 0.0 0.019 14.4 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EDO17863.1 - 0.0083 15.0 0.0 0.012 14.5 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EDO17863.1 - 0.03 13.3 0.0 0.038 12.9 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EDO17863.1 - 0.03 14.4 0.1 0.064 13.3 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EDO17863.1 - 0.096 12.6 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding SNF2_N PF00176.18 EDO17864.1 - 3.8e-83 278.7 0.4 8.2e-83 277.6 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO17864.1 - 6.7e-16 57.9 0.1 3.2e-15 55.7 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 EDO17864.1 - 3.3e-14 52.5 1.1 1.2e-13 50.7 0.7 2.0 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 EDO17864.1 - 1.1e-12 47.9 1.7 1.1e-12 47.9 1.2 4.2 2 1 1 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 EDO17864.1 - 7.2e-06 25.3 0.2 3e-05 23.3 0.1 2.2 1 0 0 1 1 1 1 QLQ HSA PF07529.8 EDO17864.1 - 0.051 13.3 12.8 0.13 12.0 6.6 3.4 2 1 1 3 3 3 0 HSA TAFII55_N PF04658.8 EDO17865.1 - 3.8e-57 192.3 0.1 3.8e-57 192.3 0.1 3.1 3 1 0 3 3 3 1 TAFII55 protein conserved region RrnaAD PF00398.15 EDO17866.1 - 2.9e-59 200.2 0.1 3.3e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase S1 PF00575.18 EDO17868.1 - 2e-62 207.2 31.6 6.5e-12 45.3 0.0 11.7 11 0 0 11 11 11 10 S1 RNA binding domain TPR_19 PF14559.1 EDO17868.1 - 2.5e-09 37.3 0.0 0.022 15.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDO17868.1 - 3.1e-06 27.6 0.0 0.23 12.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO17868.1 - 4.4e-06 26.8 0.1 0.27 11.9 0.0 4.5 3 1 2 5 5 5 2 Tetratricopeptide repeat Suf PF05843.9 EDO17868.1 - 4.1e-05 23.4 5.1 0.0002 21.1 2.0 4.7 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.7 EDO17868.1 - 0.00083 19.1 3.4 0.048 13.4 0.6 2.6 2 0 0 2 2 2 2 Mad3/BUB1 homology region 1 OapA PF04225.7 EDO17868.1 - 0.0018 18.1 1.2 0.22 11.4 0.0 3.9 2 1 1 3 3 3 1 Opacity-associated protein A LysM-like domain TPR_12 PF13424.1 EDO17868.1 - 0.037 13.9 0.3 23 5.0 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Zip PF02535.17 EDO17869.1 - 2e-38 132.1 13.7 2.2e-25 89.3 3.3 2.4 1 1 1 2 2 2 2 ZIP Zinc transporter DUF4118 PF13493.1 EDO17869.1 - 6 7.1 16.4 0.22 11.7 1.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4118) TPR_11 PF13414.1 EDO17870.1 - 3.4e-11 42.6 0.9 1.3e-06 27.9 0.2 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EDO17870.1 - 7.3e-11 41.1 0.9 0.00062 19.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO17870.1 - 2.8e-10 39.3 2.7 0.00024 20.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO17870.1 - 1.4e-09 37.7 0.5 0.0048 16.7 0.1 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO17870.1 - 1.6e-07 30.5 7.1 0.011 15.5 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDO17870.1 - 8.1e-07 28.3 0.1 0.21 11.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box PF00646.28 EDO17870.1 - 0.00021 20.8 1.1 0.00072 19.1 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EDO17870.1 - 0.0015 18.2 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like MIT PF04212.13 EDO17870.1 - 0.037 13.9 0.1 12 5.8 0.0 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_14 PF13428.1 EDO17870.1 - 0.052 14.2 0.0 16 6.4 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat APC_crr PF05923.7 EDO17870.1 - 0.063 12.9 0.1 0.17 11.5 0.1 1.8 1 0 0 1 1 1 0 APC cysteine-rich region TPR_17 PF13431.1 EDO17870.1 - 0.11 12.7 0.1 84 3.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDO17870.1 - 0.14 12.6 1.2 3.6 8.2 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDO17870.1 - 0.19 12.4 0.0 2.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3336 PF11815.3 EDO17871.1 - 3.4e-45 153.0 6.5 3.4e-45 153.0 4.5 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EDO17871.1 - 3.7e-30 105.3 0.0 6.7e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase LIM PF00412.17 EDO17872.1 - 1.2e-15 57.2 21.9 5.4e-10 39.1 6.2 2.4 2 0 0 2 2 2 2 LIM domain Whi5 PF08528.6 EDO17873.1 - 6.6e-11 41.5 0.3 1.4e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 Whi5 like Abhydrolase_6 PF12697.2 EDO17874.1 - 9e-28 97.7 0.0 1.1e-27 97.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO17874.1 - 1.6e-07 31.1 0.0 3.1e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO17874.1 - 1.5e-05 24.6 0.0 2.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EDO17874.1 - 1.8e-05 24.3 0.0 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 2 Putative esterase PGAP1 PF07819.8 EDO17874.1 - 0.017 14.6 0.0 0.058 12.9 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein ANTH PF07651.11 EDO17874.1 - 0.072 11.7 0.6 0.13 10.8 0.4 1.4 1 0 0 1 1 1 0 ANTH domain Helicase_C_3 PF13625.1 EDO17875.1 - 2e-26 92.2 0.0 5.3e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO17875.1 - 5.8e-15 55.5 0.3 7.9e-14 51.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDO17875.1 - 3.5e-12 45.7 0.0 6e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO17875.1 - 2.2e-10 40.2 1.7 3.3e-10 39.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO17875.1 - 2.6e-07 30.3 0.0 6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.1 EDO17875.1 - 0.038 13.3 0.0 0.085 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Med3 PF11593.3 EDO17875.1 - 0.9 8.7 11.4 0.12 11.5 4.7 1.7 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Pantoate_ligase PF02569.10 EDO17876.1 - 1.1e-105 352.4 0.2 1.2e-105 352.2 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase FAD_syn PF06574.7 EDO17876.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase HATPase_c PF02518.21 EDO17877.1 - 8.3e-29 99.5 0.5 1.2e-27 95.8 0.3 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDO17877.1 - 1.5e-25 89.3 0.2 3.3e-25 88.2 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EDO17877.1 - 2.2e-11 43.5 0.5 6.8e-11 42.0 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EDO17877.1 - 0.0068 16.5 3.7 0.061 13.5 0.0 2.9 3 0 0 3 3 3 1 HAMP domain ubiquitin PF00240.18 EDO17878.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 EDO17878.1 - 9.6e-31 105.1 10.9 1.5e-30 104.5 7.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EDO17878.1 - 6.5e-20 70.5 0.7 6.5e-20 70.5 0.5 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDO17878.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EDO17878.1 - 0.0001 22.0 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EDO17878.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EDO17878.1 - 0.013 15.7 0.1 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EDO17878.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Fer2_3 PF13085.1 EDO17878.1 - 0.13 12.1 1.5 0.55 10.0 1.0 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain ADIP PF11559.3 EDO17879.1 - 0.0015 18.4 15.8 0.0015 18.4 10.9 13.5 4 4 10 15 15 15 4 Afadin- and alpha -actinin-Binding zf-primase PF09329.6 EDO17880.1 - 2.5e-16 58.9 0.2 4.7e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 EDO17880.1 - 0.074 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Pcc1 PF09341.5 EDO17881.1 - 4.2e-25 87.5 0.0 4.6e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 PIN_4 PF13638.1 EDO17882.1 - 4.8e-11 42.8 0.3 2.2e-10 40.7 0.2 2.2 1 0 0 1 1 1 1 PIN domain PEPCK_ATP PF01293.15 EDO17884.1 - 1.8e-218 725.7 0.0 2.2e-218 725.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 EDO17884.1 - 0.036 13.9 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDO17884.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EDO17884.1 - 0.15 11.6 0.5 0.33 10.4 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nop14 PF04147.7 EDO17885.1 - 0.013 13.4 17.1 0.015 13.3 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 EDO17885.1 - 0.021 14.3 9.3 0.05 13.1 6.5 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.5 EDO17885.1 - 0.027 13.5 12.6 0.045 12.8 8.8 1.4 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.3 EDO17885.1 - 0.063 13.1 16.1 0.11 12.3 11.2 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PBP_sp32 PF07222.7 EDO17885.1 - 0.27 10.3 8.2 0.49 9.5 5.7 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FAM176 PF14851.1 EDO17885.1 - 0.29 10.8 9.4 0.63 9.7 6.5 1.5 1 0 0 1 1 1 0 FAM176 family FYDLN_acid PF09538.5 EDO17885.1 - 0.36 11.4 15.7 0.8 10.3 10.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) RXT2_N PF08595.6 EDO17885.1 - 0.47 10.2 10.6 1.2 8.9 7.4 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Paf1 PF03985.8 EDO17885.1 - 0.79 8.3 15.5 1.5 7.4 10.7 1.4 1 0 0 1 1 1 0 Paf1 Myc_N PF01056.13 EDO17885.1 - 1.4 8.0 8.5 2.5 7.2 5.9 1.5 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.7 EDO17885.1 - 2 7.5 17.3 3.4 6.8 12.0 1.3 1 0 0 1 1 1 0 NOA36 protein BSP_II PF05432.6 EDO17885.1 - 5.1 6.2 22.3 0.2 10.8 11.2 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TFIIA PF03153.8 EDO17885.1 - 5.8 6.7 16.6 8.6 6.1 11.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DAO PF01266.19 EDO17886.1 - 3.4e-51 174.2 0.0 4.5e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EDO17886.1 - 1.2e-14 54.0 0.3 3e-14 52.7 0.2 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EDO17886.1 - 5.7e-12 45.4 5.4 1.3e-10 40.9 3.8 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EDO17886.1 - 2.4e-08 34.1 0.6 2.6e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDO17886.1 - 4.4e-06 25.9 0.4 0.012 14.7 0.0 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 EDO17886.1 - 9.2e-06 24.9 0.1 0.041 12.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EDO17886.1 - 2e-05 23.6 2.3 0.0011 17.9 0.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.9 EDO17886.1 - 2.5e-05 22.9 0.2 4.6e-05 22.0 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EDO17886.1 - 0.00012 22.0 0.5 0.00039 20.4 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EDO17886.1 - 0.0046 16.6 1.2 0.03 13.9 0.9 2.4 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EDO17886.1 - 0.0065 16.5 0.9 0.21 11.6 0.4 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO17886.1 - 0.011 16.0 0.7 0.04 14.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EDO17886.1 - 0.035 13.0 0.4 0.1 11.5 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein DUF1748 PF08520.5 EDO17887.1 - 4.8e-32 109.4 0.0 5.3e-32 109.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Coa1 PF08695.5 EDO17888.1 - 5e-40 135.6 0.0 9.6e-40 134.7 0.0 1.4 2 0 0 2 2 2 1 Cytochrome oxidase complex assembly protein 1 Flu_B_M2 PF04772.7 EDO17888.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) CENP-B_dimeris PF09026.5 EDO17889.1 - 0.54 10.5 12.8 0.89 9.8 2.4 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ribosomal_L18ae PF01775.12 EDO17891.1 - 3.5e-45 152.8 3.6 4.8e-45 152.4 2.5 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain CTP_transf_1 PF01148.15 EDO17892.1 - 3.3e-21 76.1 14.8 1.1e-18 67.7 4.6 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family Nop PF01798.13 EDO17893.1 - 1.9e-59 199.2 1.0 5.3e-59 197.8 0.7 1.8 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EDO17893.1 - 1.3e-27 95.3 0.1 3.1e-27 94.1 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EDO17893.1 - 8.9e-19 67.4 2.0 8.9e-19 67.4 1.4 3.1 2 1 0 2 2 2 1 NOP5NT (NUC127) domain Aldolase PF01081.14 EDO17893.1 - 0.12 11.5 0.0 0.28 10.3 0.0 1.7 1 0 0 1 1 1 0 KDPG and KHG aldolase GAGA_bind PF06217.7 EDO17893.1 - 4.6 7.1 25.9 1.8 8.4 15.6 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family DUF382 PF04037.8 EDO17894.1 - 2.5e-51 172.8 0.0 7.5e-51 171.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EDO17894.1 - 1.9e-22 78.3 0.4 3.5e-22 77.5 0.3 1.5 1 0 0 1 1 1 1 PSP MS_channel PF00924.13 EDO17894.1 - 0.23 10.7 0.6 0.46 9.7 0.4 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel SLIDE PF09111.5 EDO17895.1 - 1.3e-42 144.2 3.9 1.3e-42 144.2 2.7 2.6 2 1 0 2 2 2 1 SLIDE HAND PF09110.6 EDO17895.1 - 7.6e-40 135.8 12.0 7.6e-40 135.8 8.4 2.6 2 1 0 2 2 2 1 HAND DUF1086 PF06461.6 EDO17895.1 - 0.036 13.8 1.1 0.074 12.8 0.2 2.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1086) Myb_DNA-binding PF00249.26 EDO17895.1 - 0.044 13.8 0.0 0.14 12.1 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain SNF2_N PF00176.18 EDO17896.1 - 2.8e-82 275.8 0.8 5.3e-82 274.9 0.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EDO17896.1 - 8.3e-17 60.8 0.0 3.8e-16 58.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO17896.1 - 8.2e-12 45.3 0.0 8.2e-12 45.3 0.0 3.4 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDO17896.1 - 2.5e-08 33.6 0.0 8.8e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EDO17896.1 - 0.013 15.3 1.4 0.051 13.4 0.1 2.6 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EDO17896.1 - 0.019 15.1 0.4 0.078 13.1 0.1 2.3 2 1 0 2 2 2 0 AAA domain DEAD_2 PF06733.10 EDO17896.1 - 0.031 13.6 0.5 0.074 12.4 0.4 1.6 1 0 0 1 1 1 0 DEAD_2 CPSase_sm_chain PF00988.17 EDO17897.1 - 5.1e-46 155.4 0.0 9.4e-46 154.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EDO17897.1 - 1.1e-43 148.9 0.0 1.6e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDO17897.1 - 2.4e-06 27.1 0.4 7.3e-05 22.3 0.1 2.7 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.19 EDO17897.1 - 0.00047 19.6 0.0 0.00078 18.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family RGS PF00615.14 EDO17898.1 - 0.00011 22.2 0.3 0.0081 16.2 0.0 2.5 2 0 0 2 2 2 1 Regulator of G protein signaling domain Ctr PF04145.10 EDO17898.1 - 0.079 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Ctr copper transporter family ChAPs PF09295.5 EDO17899.1 - 2.8e-164 546.6 2.2 3.5e-164 546.2 1.5 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) Apc3 PF12895.2 EDO17899.1 - 0.0037 17.3 1.1 1.5 9.0 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EDO17899.1 - 0.0045 16.8 0.1 0.52 10.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO17899.1 - 0.013 16.0 0.1 62 4.6 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDO17899.1 - 0.018 15.4 0.0 62 4.3 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDO17899.1 - 0.15 12.7 0.0 6 7.6 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIID-31kDa PF02291.10 EDO17900.1 - 7.7e-52 174.4 0.1 3.7e-29 101.1 0.0 2.0 2 0 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit M_domain PF12938.2 EDO17900.1 - 0.01 15.6 1.2 0.013 15.3 0.8 1.2 1 0 0 1 1 1 0 M domain of GW182 Gly-zipper_OmpA PF13436.1 EDO17900.1 - 2.5 7.7 15.3 4 7.1 10.6 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Fip1 PF05182.8 EDO17901.1 - 1.3e-22 78.7 0.6 2.8e-22 77.7 0.4 1.6 1 0 0 1 1 1 1 Fip1 motif UAE_UbL PF14732.1 EDO17901.1 - 0.1 12.6 0.6 0.23 11.5 0.4 1.6 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Flavi_glycoprot PF00869.15 EDO17902.1 - 0.04 12.8 0.1 0.067 12.1 0.1 1.3 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains PUF PF00806.14 EDO17904.1 - 3.5e-29 98.5 2.8 0.0002 20.6 0.0 6.8 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_5 PF13893.1 EDO17904.1 - 2.7e-08 33.5 0.0 7.5e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO17904.1 - 1.2e-05 24.8 0.0 2.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO17904.1 - 0.012 15.5 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 EDO17905.1 - 1.8e-06 27.5 0.7 5.1e-06 26.1 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO17905.1 - 2e-05 24.1 0.3 7.3e-05 22.3 0.2 2.0 1 0 0 1 1 1 1 F-box domain G-gamma PF00631.17 EDO17906.1 - 1e-23 82.8 0.2 1.3e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 GGL domain PCI PF01399.22 EDO17907.1 - 5.6e-09 36.2 0.3 6.8e-08 32.7 0.2 2.5 1 1 0 1 1 1 1 PCI domain YbfN PF13982.1 EDO17907.1 - 0.033 14.3 0.9 0.075 13.2 0.1 2.0 2 0 0 2 2 2 0 YbfN-like lipoprotein V-ATPase_H_N PF03224.9 EDO17909.1 - 3.1e-62 210.4 10.6 3.1e-62 210.4 7.3 1.9 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EDO17909.1 - 3.6e-39 133.3 1.7 3.6e-39 133.3 1.2 3.1 2 2 1 3 3 3 1 V-ATPase subunit H bPH_6 PF10756.4 EDO17909.1 - 0.13 12.2 0.1 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain Lgl_C PF08596.5 EDO17910.1 - 3.5e-138 460.3 0.4 6.3e-138 459.5 0.3 1.4 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EDO17910.1 - 0.00098 18.9 0.9 4.4 7.3 0.0 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat Proteasome PF00227.21 EDO17910.1 - 0.018 14.3 0.1 0.046 12.9 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit HLH PF00010.21 EDO17911.1 - 3.4e-16 58.6 0.4 6.4e-16 57.7 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CAF-1_p150 PF11600.3 EDO17911.1 - 5.6 6.2 10.1 1.1 8.5 4.2 2.0 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Got1 PF04178.7 EDO17912.1 - 5e-30 104.0 17.9 7.1e-30 103.5 12.4 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Arrestin_C PF02752.17 EDO17913.1 - 1.8e-14 54.0 0.9 1.8e-14 54.0 0.6 3.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EDO17913.1 - 0.00027 20.7 0.0 0.0053 16.5 0.0 2.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain KRTAP PF11759.3 EDO17914.1 - 0.053 13.7 1.4 0.15 12.3 1.0 1.7 1 0 0 1 1 1 0 Keratin-associated matrix Glyco_hydro_16 PF00722.16 EDO17915.1 - 4.6e-46 156.4 1.2 4.6e-46 156.4 0.8 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 AA_permease PF00324.16 EDO17916.1 - 5.3e-134 447.1 36.9 6.4e-134 446.8 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO17916.1 - 2.5e-38 131.7 39.3 3.1e-38 131.4 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease EIF_2_alpha PF07541.7 EDO17917.1 - 1.2e-41 140.9 0.6 2.3e-41 140.1 0.1 1.6 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EDO17917.1 - 1.4e-14 53.8 1.2 3.2e-14 52.7 0.9 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 EDO17917.1 - 0.062 13.2 0.3 0.17 11.8 0.2 1.8 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 RcsC PF09456.5 EDO17917.1 - 0.065 12.8 0.1 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) FGGY_N PF00370.16 EDO17918.1 - 4e-22 78.7 0.0 1.7e-12 47.1 0.0 2.5 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EDO17918.1 - 1.6e-14 54.0 0.0 7.2e-06 25.7 0.0 3.1 3 0 0 3 3 3 2 FGGY family of carbohydrate kinases, C-terminal domain SPC12 PF06645.8 EDO17919.1 - 5.7e-22 77.3 1.8 6.4e-22 77.1 1.3 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF1673 PF07895.6 EDO17919.1 - 0.11 12.0 0.5 0.12 11.8 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) DUF2207 PF09972.4 EDO17919.1 - 0.16 10.5 0.7 0.14 10.7 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Vma12 PF11712.3 EDO17919.1 - 0.24 11.0 1.1 0.31 10.7 0.8 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3102 PF11300.3 EDO17920.1 - 0.048 13.6 0.4 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3102) FMN_bind PF04205.9 EDO17920.1 - 0.13 12.4 1.1 24 5.2 0.0 2.6 2 1 0 2 2 2 0 FMN-binding domain Ribosomal_L29 PF00831.18 EDO17920.1 - 0.23 11.1 4.5 0.24 11.0 1.2 2.3 2 0 0 2 2 2 0 Ribosomal L29 protein Myb_DNA-bind_3 PF12776.2 EDO17920.1 - 0.39 11.3 5.2 2.6 8.7 0.3 2.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Mannosyl_trans PF05007.8 EDO17922.1 - 1.7e-80 270.3 32.1 1.7e-80 270.3 22.2 2.4 2 2 0 3 3 3 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EDO17922.1 - 3.2e-10 39.4 44.8 6.9e-10 38.3 31.0 1.5 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EDO17922.1 - 0.00011 21.7 0.2 0.00011 21.7 0.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) RNase_PH PF01138.16 EDO17923.1 - 1.6e-27 96.4 0.1 2.3e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDO17923.1 - 1.3e-05 25.0 0.3 4.2e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 HP_OMP_2 PF02521.9 EDO17923.1 - 0.029 12.9 0.0 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative outer membrane protein CC2D2AN-C2 PF15625.1 EDO17923.1 - 0.055 12.9 0.4 0.22 10.9 0.1 1.8 2 0 0 2 2 2 0 CC2D2A N-terminal C2 domain CTP_transf_2 PF01467.21 EDO17924.1 - 1.6e-25 90.0 0.0 2.9e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase RXT2_N PF08595.6 EDO17924.1 - 1.4 8.6 12.4 4.4 7.1 5.0 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Rotamase PF00639.16 EDO17925.1 - 4.7e-26 91.3 0.2 6.2e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EDO17925.1 - 1.4e-18 67.2 0.0 1.8e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EDO17925.1 - 1.1e-08 34.8 0.5 1.6e-08 34.2 0.3 1.3 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EDO17925.1 - 4.5e-08 33.7 0.1 8.1e-08 32.9 0.0 1.5 2 1 0 2 2 2 1 PPIC-type PPIASE domain DUF501 PF04417.7 EDO17925.1 - 0.056 13.3 2.3 3.5 7.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF501) LSM PF01423.17 EDO17926.1 - 7.3e-12 44.6 0.1 1.2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain ETF PF01012.16 EDO17927.1 - 1e-28 100.1 0.0 1.3e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain GatB_Yqey PF02637.13 EDO17927.1 - 0.099 12.3 0.3 0.099 12.3 0.2 1.9 2 0 0 2 2 2 0 GatB domain TFIIE_beta PF02186.10 EDO17927.1 - 0.67 9.9 5.1 3.3 7.7 0.3 3.1 2 1 0 2 2 2 0 TFIIE beta subunit core domain Thioredoxin PF00085.15 EDO17928.1 - 9.5e-16 57.3 0.0 1e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EDO17928.1 - 0.0042 15.8 0.0 0.0047 15.6 0.0 1.0 1 0 0 1 1 1 1 Phosducin DIM1 PF02966.11 EDO17928.1 - 0.016 14.6 0.1 0.018 14.5 0.1 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_2 PF13098.1 EDO17928.1 - 0.043 14.0 0.7 0.19 11.9 0.5 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain DUF836 PF05768.9 EDO17928.1 - 0.078 13.2 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.1 EDO17928.1 - 0.12 12.1 0.1 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin domain RRM_5 PF13893.1 EDO17929.1 - 0.00014 21.5 1.5 0.00022 20.9 0.2 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EAP30 PF04157.11 EDO17929.1 - 0.065 12.3 2.3 0.13 11.3 1.6 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family Astro_capsid PF03115.9 EDO17929.1 - 0.78 7.9 5.8 0.98 7.5 4.0 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor ATG16 PF08614.6 EDO17930.1 - 9.3e-05 22.3 13.0 9.3e-05 22.3 9.0 2.4 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) HEAT PF02985.17 EDO17930.1 - 0.015 15.2 0.0 56 4.2 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat Ipi1_N PF12333.3 EDO17930.1 - 0.016 15.1 5.9 0.084 12.8 0.0 4.4 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation DUF3450 PF11932.3 EDO17930.1 - 0.25 10.5 13.4 0.7 9.1 9.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HrpB7 PF09486.5 EDO17930.1 - 0.68 9.8 4.9 0.22 11.4 0.9 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Thioredoxin PF00085.15 EDO17931.1 - 4.9e-32 109.7 0.4 5.5e-32 109.5 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EDO17931.1 - 1.8e-10 40.9 0.3 2e-09 37.6 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDO17931.1 - 1e-07 31.9 0.2 8.5e-06 25.8 0.1 2.0 1 1 1 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 EDO17931.1 - 2.4e-06 27.1 0.7 0.0015 18.0 0.1 2.0 1 1 1 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EDO17931.1 - 2.2e-05 24.0 0.0 2.4e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.11 EDO17931.1 - 9.9e-05 21.8 0.1 0.00011 21.6 0.1 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 AhpC-TSA PF00578.16 EDO17931.1 - 0.00018 21.1 0.4 0.00043 19.9 0.3 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EDO17931.1 - 0.0016 18.4 0.2 0.0028 17.6 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 EDO17931.1 - 0.04 13.9 0.1 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin TPP_enzyme_M PF00205.17 EDO17932.1 - 9.4e-38 129.0 0.1 4.1e-37 126.9 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 EDO17932.1 - 1.3e-32 112.6 0.1 2e-32 112.0 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EDO17932.1 - 1.7e-14 53.6 0.0 2.9e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain AATase PF07247.7 EDO17933.1 - 1.9e-64 217.9 7.5 2.4e-64 217.6 5.2 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Cortex-I_coil PF09304.5 EDO17933.1 - 0.04 13.9 0.3 0.087 12.8 0.2 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil Ferric_reduct PF01794.14 EDO17934.1 - 1.7e-19 70.1 11.2 1.7e-19 70.1 7.8 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EDO17934.1 - 0.0045 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EDO17934.1 - 0.012 15.5 0.0 0.077 12.9 0.0 2.3 1 1 0 1 1 1 0 Ferric reductase NAD binding domain MORN_2 PF07661.8 EDO17934.1 - 0.09 12.8 0.6 0.31 11.2 0.4 1.9 1 0 0 1 1 1 0 MORN repeat variant Ribosomal_S2 PF00318.15 EDO17935.1 - 1.9e-39 135.1 0.0 2.8e-20 72.4 0.0 2.9 2 1 1 3 3 3 2 Ribosomal protein S2 MRP-S33 PF08293.6 EDO17936.1 - 4.7e-32 109.8 0.7 5.6e-32 109.5 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ion_trans PF00520.26 EDO17937.1 - 2.7e-29 101.8 16.7 2.7e-29 101.8 11.6 3.5 3 1 0 3 3 3 2 Ion transport protein DUF957 PF06117.6 EDO17937.1 - 0.14 11.7 3.4 0.074 12.6 0.3 2.1 2 0 0 2 2 2 0 Enterobacterial protein of unknown function (DUF957) Ion_trans PF00520.26 EDO17938.1 - 8e-40 136.2 42.9 3.4e-26 91.7 10.9 3.7 4 0 0 4 4 4 2 Ion transport protein DUF4381 PF14316.1 EDO17938.1 - 0.051 13.6 0.2 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) CRM1_C PF08767.6 EDO17939.1 - 4.2e-101 338.0 18.5 4.2e-101 338.0 12.8 3.1 3 2 2 5 5 5 1 CRM1 C terminal Xpo1 PF08389.7 EDO17939.1 - 4e-25 88.4 4.3 4e-25 88.4 3.0 3.3 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.14 EDO17939.1 - 8.2e-12 44.8 0.0 3.9e-11 42.6 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain SKG6 PF08693.5 EDO17940.1 - 3.7e-12 45.3 1.8 3.7e-12 45.3 1.3 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EDO17940.1 - 1.1e-05 25.0 0.2 2.8e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Rax2 PF12768.2 EDO17940.1 - 0.00014 21.1 1.9 0.00031 20.0 0.0 2.2 2 0 0 2 2 2 1 Cortical protein marker for cell polarity TMEM154 PF15102.1 EDO17940.1 - 0.00027 20.6 4.2 0.00055 19.6 0.0 2.5 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.1 EDO17940.1 - 0.00062 20.1 0.0 0.0064 16.8 0.0 2.5 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.7 EDO17940.1 - 0.00091 18.6 0.7 0.00091 18.6 0.5 2.1 3 0 0 3 3 3 1 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.10 EDO17940.1 - 0.0027 17.2 0.2 0.0053 16.2 0.1 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF912 PF06024.7 EDO17940.1 - 0.0032 17.4 0.1 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Syndecan PF01034.15 EDO17940.1 - 0.039 13.6 0.1 0.087 12.4 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain DUF1191 PF06697.7 EDO17940.1 - 0.071 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF2973 PF11189.3 EDO17940.1 - 0.14 11.9 0.1 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) DUF2453 PF10507.4 EDO17940.1 - 0.18 11.6 0.3 5.6 6.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2453) Shisa PF13908.1 EDO17940.1 - 0.46 10.6 0.0 0.46 10.6 0.0 2.9 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator SMI1_KNR4 PF09346.5 EDO17941.1 - 4.6e-37 126.9 0.0 1.5e-35 122.0 0.0 3.2 1 1 1 2 2 2 1 SMI1 / KNR4 family (SUKH-1) Ank_2 PF12796.2 EDO17942.1 - 5e-34 116.5 0.0 1.2e-16 60.8 0.0 3.9 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDO17942.1 - 8e-31 104.3 0.0 1e-06 28.2 0.0 6.7 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EDO17942.1 - 2.7e-29 101.0 2.6 2.6e-10 40.5 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) SPX PF03105.14 EDO17942.1 - 1.6e-27 97.0 27.4 8.5e-19 68.3 7.3 3.0 2 1 1 3 3 3 2 SPX domain Ank_3 PF13606.1 EDO17942.1 - 7.3e-27 90.7 0.0 0.0008 19.4 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EDO17942.1 - 1.8e-21 75.6 0.0 0.00013 22.1 0.0 6.1 2 2 4 6 6 6 6 Ankyrin repeats (many copies) HATPase_c_4 PF13749.1 EDO17943.1 - 0.042 13.6 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal Kelch_3 PF13415.1 EDO17944.1 - 3.1e-36 122.7 0.3 9.3e-07 28.8 0.0 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EDO17944.1 - 1.1e-27 95.5 12.9 1.7e-06 27.7 0.2 6.9 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EDO17944.1 - 5.6e-26 90.0 3.0 0.00017 21.4 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EDO17944.1 - 3.2e-22 77.7 0.7 3.6e-06 26.4 0.1 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 EDO17944.1 - 2.1e-21 75.1 7.5 1e-05 25.5 0.1 6.8 6 1 1 7 7 7 5 Kelch motif Kelch_2 PF07646.10 EDO17944.1 - 5.8e-12 44.8 4.4 0.44 10.3 0.1 6.1 6 1 0 6 6 6 5 Kelch motif MPC PF03650.8 EDO17945.1 - 1.6e-48 163.5 0.2 2e-48 163.3 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) SDA1 PF05285.7 EDO17946.1 - 1.7e-91 306.9 27.3 1.7e-91 306.9 18.9 2.2 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.7 EDO17946.1 - 8e-23 80.4 0.9 3e-22 78.6 0.1 2.3 2 0 0 2 2 2 1 NUC130/3NT domain TIM21 PF08294.6 EDO17946.1 - 0.46 10.1 3.9 0.25 11.0 0.1 2.3 2 0 0 2 2 2 0 TIM21 TFIIB PF00382.14 EDO17947.1 - 1.4e-55 184.9 0.9 7e-28 96.2 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EDO17947.1 - 9.8e-32 109.0 4.5 9.8e-32 109.0 3.1 2.3 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EDO17947.1 - 2.1e-08 33.3 3.2 4.2e-08 32.3 2.2 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EDO17947.1 - 9.1e-06 25.2 0.5 0.012 15.1 0.0 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain DUF3393 PF11873.3 EDO17947.1 - 1.5 8.3 7.6 0.15 11.5 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3393) Fibrillarin PF01269.12 EDO17948.1 - 1e-109 364.8 0.0 1.3e-109 364.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EDO17948.1 - 2.3e-05 24.0 0.1 4.2e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EDO17948.1 - 0.082 12.4 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Steroid_dh PF02544.11 EDO17949.1 - 1.2e-32 112.7 11.1 1.2e-32 112.7 7.7 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF2479 PF10651.4 EDO17949.1 - 0.072 12.6 1.0 0.12 11.8 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2479) Pkinase PF00069.20 EDO17950.1 - 1.9e-40 138.6 0.1 2.7e-22 79.1 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17950.1 - 1.5e-15 56.9 0.0 1e-09 37.8 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 EDO17950.1 - 0.00088 18.3 0.0 0.63 8.9 0.0 2.6 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EDO17950.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family HEAT PF02985.17 EDO17951.1 - 1.8e-21 74.1 7.4 0.00075 19.3 0.0 8.4 8 0 0 8 8 8 5 HEAT repeat HEAT_EZ PF13513.1 EDO17951.1 - 1.1e-20 73.5 0.7 8.9e-11 41.9 0.0 7.7 8 0 0 8 8 8 3 HEAT-like repeat HEAT_2 PF13646.1 EDO17951.1 - 6.9e-15 55.1 0.0 1.3e-05 25.3 0.0 6.1 5 2 1 6 6 6 4 HEAT repeats Adaptin_N PF01602.15 EDO17951.1 - 2.6e-08 32.6 5.5 0.0062 14.9 0.0 4.6 4 1 0 4 4 4 3 Adaptin N terminal region Cnd1 PF12717.2 EDO17951.1 - 5e-06 26.4 3.8 0.068 13.0 0.0 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EDO17951.1 - 4.8e-05 23.6 0.1 0.18 12.1 0.0 4.6 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EDO17951.1 - 0.00022 21.0 3.0 0.0012 18.7 0.1 3.8 3 1 0 3 3 3 1 Importin-beta N-terminal domain SH3_1 PF00018.23 EDO17952.1 - 3.5e-10 39.1 0.8 4.7e-09 35.4 0.0 2.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EDO17952.1 - 0.00046 19.7 0.0 0.0012 18.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Orthopox_F14 PF06076.7 EDO17953.1 - 0.15 12.1 3.1 0.32 11.0 0.1 2.8 2 0 0 2 2 2 0 Orthopoxvirus F14 protein Med2 PF11214.3 EDO17954.1 - 1.9e-23 82.4 63.6 3.5e-22 78.4 36.3 4.3 3 1 0 3 3 3 1 Mediator complex subunit 2 MIP-T3 PF10243.4 EDO17954.1 - 0.0014 17.1 32.7 0.002 16.6 22.6 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 EDO17954.1 - 5.7 4.9 44.0 0.16 10.1 23.4 2.0 2 0 0 2 2 2 0 Utp14 protein PP2C PF00481.16 EDO17955.1 - 1.9e-74 250.3 0.1 8.2e-74 248.2 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EDO17955.1 - 4.9e-05 23.1 0.1 0.00022 20.9 0.1 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Trp_oprn_chp PF09534.5 EDO17955.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AAA PF00004.24 EDO17956.1 - 1.4e-40 138.5 0.0 2.5e-40 137.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO17956.1 - 1.9e-06 28.0 0.2 0.00043 20.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EDO17956.1 - 6.1e-06 26.2 0.0 1.8e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EDO17956.1 - 1.6e-05 23.9 0.0 2.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EDO17956.1 - 3.9e-05 23.4 0.0 0.00019 21.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO17956.1 - 0.00015 21.8 0.0 0.0015 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EDO17956.1 - 0.0009 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EDO17956.1 - 0.0016 18.4 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO17956.1 - 0.0023 17.8 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO17956.1 - 0.0043 17.8 0.5 0.012 16.3 0.1 2.0 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EDO17956.1 - 0.0068 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EDO17956.1 - 0.0072 16.0 0.3 0.015 15.0 0.2 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EDO17956.1 - 0.0073 16.6 0.1 0.022 15.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EDO17956.1 - 0.0093 15.3 1.6 0.19 11.1 0.3 2.4 1 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EDO17956.1 - 0.0099 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EDO17956.1 - 0.01 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EDO17956.1 - 0.011 15.2 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EDO17956.1 - 0.018 13.9 0.0 0.048 12.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.8 EDO17956.1 - 0.019 13.7 0.0 0.035 12.8 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus NTPase_1 PF03266.10 EDO17956.1 - 0.02 14.5 0.1 0.19 11.4 0.0 2.5 2 0 0 2 2 2 0 NTPase NACHT PF05729.7 EDO17956.1 - 0.028 14.0 0.1 0.32 10.6 0.1 2.3 1 1 0 2 2 2 0 NACHT domain KaiC PF06745.8 EDO17956.1 - 0.037 13.1 0.2 0.41 9.7 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.17 EDO17956.1 - 0.037 14.1 0.0 0.087 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EDO17956.1 - 0.047 13.2 0.2 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EDO17956.1 - 0.049 12.7 0.1 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EDO17956.1 - 0.054 12.7 0.2 0.19 10.9 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 EDO17956.1 - 0.13 12.5 1.0 1.2 9.4 0.7 2.4 1 1 0 1 1 1 0 ABC transporter Pkinase PF00069.20 EDO17957.1 - 3e-63 213.4 0.1 4.8e-63 212.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO17957.1 - 1.3e-32 112.9 0.0 2.2e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO17957.1 - 1.5e-07 30.7 0.0 7.9e-07 28.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EDO17957.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO17957.1 - 0.078 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Complex1_LYR PF05347.10 EDO17958.1 - 0.023 14.5 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Complex 1 protein (LYR family) PTS_2-RNA PF01885.11 EDO17959.1 - 3.5e-57 192.7 1.1 4.5e-57 192.3 0.7 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PARP PF00644.15 EDO17959.1 - 0.037 13.4 0.2 0.068 12.5 0.2 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain CPL PF08144.6 EDO17961.1 - 4e-18 65.6 0.0 2.6e-16 59.8 0.0 3.2 3 0 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.14 EDO17961.1 - 3.4e-08 32.5 2.9 0.23 11.0 0.0 5.5 6 0 0 6 6 6 3 Pumilio-family RNA binding repeat DUF4253 PF14062.1 EDO17961.1 - 0.085 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) BUD22 PF09073.5 EDO17961.1 - 0.14 11.2 27.4 0.23 10.4 19.0 1.4 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.6 EDO17961.1 - 0.23 9.5 10.7 1.5 6.8 5.0 2.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 EDO17961.1 - 1.2 7.5 23.5 2.1 6.7 16.3 1.3 1 0 0 1 1 1 0 Daxx Family Sec20 PF03908.8 EDO17962.1 - 8.9e-29 99.0 2.6 8.9e-29 99.0 1.8 3.0 3 0 0 3 3 3 1 Sec20 DUF3086 PF11285.3 EDO17962.1 - 0.017 13.9 0.7 0.29 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) DUF1542 PF07564.6 EDO17962.1 - 2.9 7.9 8.6 0.17 11.9 1.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) NeuB PF03102.9 EDO17963.1 - 0.036 13.2 0.1 2.8 7.0 0.0 2.4 2 0 0 2 2 2 0 NeuB family RNase_P_pop3 PF08228.6 EDO17964.1 - 1.3e-47 161.5 0.9 1.6e-47 161.2 0.7 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 WSC PF01822.14 EDO17965.1 - 1.5e-14 53.6 12.6 1.5e-14 53.6 8.7 2.5 2 1 0 2 2 2 1 WSC domain Adeno_E3_CR2 PF02439.10 EDO17965.1 - 1.7e-05 24.2 1.1 3.8e-05 23.1 0.7 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.5 EDO17965.1 - 4.1e-05 22.7 1.1 4.1e-05 22.7 0.8 2.8 4 0 0 4 4 4 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EDO17965.1 - 0.0022 18.3 0.0 0.014 15.7 0.0 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 EDO17965.1 - 0.0034 17.0 3.5 0.0071 16.0 2.5 1.5 1 1 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 EDO17965.1 - 0.027 14.1 0.0 0.027 14.1 0.0 3.1 1 1 2 3 3 3 0 TMEM154 protein family Syndecan PF01034.15 EDO17965.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Yip1 PF04893.12 EDO17965.1 - 0.083 12.3 0.2 0.083 12.3 0.1 1.7 2 0 0 2 2 2 0 Yip1 domain ODV-E18 PF10717.4 EDO17965.1 - 0.29 10.5 0.0 0.29 10.5 0.0 3.3 4 0 0 4 4 4 0 Occlusion-derived virus envelope protein ODV-E18 PsbJ PF01788.12 EDO17965.1 - 0.91 9.1 7.1 2.2 7.8 4.9 1.6 1 0 0 1 1 1 0 PsbJ rve PF00665.21 EDO17966.1 - 6.8e-14 52.0 0.0 1.4e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EDO17966.1 - 0.00083 18.8 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF4306 PF14154.1 EDO17966.1 - 0.018 14.9 0.2 0.042 13.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Aconitase PF00330.15 EDO17966.1 - 0.03 12.8 0.0 0.041 12.3 0.0 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) DUF1751 PF08551.5 EDO17967.1 - 1e-28 99.5 0.9 1e-28 99.5 0.6 2.6 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EDO17967.1 - 0.0011 18.9 6.6 0.0011 18.9 4.6 1.6 2 0 0 2 2 2 1 Rhomboid family HLH PF00010.21 EDO17968.1 - 0.0059 16.2 1.3 0.0079 15.8 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3683 PF12447.3 EDO17968.1 - 0.024 14.4 1.4 0.42 10.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) Oxidored_FMN PF00724.15 EDO17969.1 - 1e-129 432.4 0.0 1.2e-129 432.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cation_ATPase_N PF00690.21 EDO17969.1 - 0.16 11.4 0.3 0.31 10.5 0.0 1.6 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus TPR_11 PF13414.1 EDO17970.1 - 9.1e-06 25.2 0.4 0.056 13.0 0.0 2.4 2 0 0 2 2 2 2 TPR repeat TPR_7 PF13176.1 EDO17970.1 - 3.8e-05 23.1 1.3 0.018 14.7 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO17970.1 - 0.00022 21.0 2.0 0.018 14.9 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO17970.1 - 0.0031 17.3 2.0 0.12 12.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EDO17970.1 - 0.0032 17.0 3.3 0.14 11.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO17970.1 - 0.0039 17.8 0.0 2.7 8.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO17970.1 - 0.017 15.2 0.4 6.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Daxx PF03344.10 EDO17970.1 - 0.035 12.6 19.3 0.042 12.3 13.4 1.2 1 0 0 1 1 1 0 Daxx Family TPR_8 PF13181.1 EDO17970.1 - 0.14 12.0 0.3 0.14 12.0 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat UPF0121 PF03661.8 EDO17971.1 - 1.5e-14 53.8 9.0 2.2e-14 53.2 6.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) HSP70 PF00012.15 EDO17972.1 - 6.4e-272 902.8 11.2 7.2e-272 902.6 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO17972.1 - 4.5e-16 58.3 0.9 4.8e-15 54.9 0.0 2.3 3 0 0 3 3 3 1 MreB/Mbl protein DDR PF08841.5 EDO17972.1 - 0.0013 17.6 0.6 0.024 13.5 0.1 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EDO17972.1 - 0.0035 16.9 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EDO17972.1 - 0.022 13.8 1.7 0.18 10.8 0.0 2.8 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase Miro PF08477.8 EDO17972.1 - 0.085 13.3 1.1 0.21 12.0 0.4 2.0 2 0 0 2 2 2 0 Miro-like protein DUF1484 PF07363.6 EDO17972.1 - 0.1 12.9 1.1 14 6.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1484) PMBR PF09373.5 EDO17972.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat Tim17 PF02466.14 EDO17974.1 - 6.9e-49 165.1 1.6 8.6e-49 164.8 1.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family YgaB PF14182.1 EDO17975.1 - 0.52 10.5 5.9 0.37 11.0 0.2 2.8 2 0 0 2 2 2 0 YgaB-like protein SOBP PF15279.1 EDO17975.1 - 9 6.5 16.1 0.52 10.6 2.2 2.1 1 1 1 2 2 2 0 Sine oculis-binding protein KIAA1328 PF15369.1 EDO17976.1 - 5.5 6.7 8.6 7.5 6.2 5.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Rap1-DNA-bind PF09197.5 EDO17976.1 - 7.4 7.1 17.4 74 3.9 3.5 3.3 1 1 2 3 3 3 0 Rap1, DNA-binding Chitin_synth_1 PF01644.12 EDO17977.1 - 7.3e-76 253.4 0.4 1.2e-75 252.7 0.3 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EDO17977.1 - 3.8e-26 90.5 0.1 1.6e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EDO17977.1 - 1.3e-19 69.9 9.4 3.5e-14 52.0 0.0 2.6 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EDO17977.1 - 6.9e-13 48.7 0.9 2.3e-12 47.0 0.6 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDO17977.1 - 1.1e-10 41.7 0.0 2.5e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 SUR7 PF06687.7 EDO17979.1 - 6.9e-34 117.2 8.0 8.6e-34 116.9 5.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EDO17979.1 - 0.0016 18.1 4.4 0.0016 18.1 3.1 2.2 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Doppel PF11466.3 EDO17979.1 - 0.12 11.9 0.3 0.3 10.6 0.2 1.7 1 0 0 1 1 1 0 Prion-like protein Doppel VIT1 PF01988.14 EDO17980.1 - 5.4 6.4 8.0 15 4.9 5.5 1.7 1 0 0 1 1 1 0 VIT family YtxH PF12732.2 EDO17980.1 - 6.5 7.2 7.0 11 6.4 4.5 1.8 1 1 0 1 1 1 0 YtxH-like protein RRM_1 PF00076.17 EDO17981.1 - 7.8e-20 70.2 0.0 9.2e-16 57.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO17981.1 - 2.4e-08 33.8 0.0 1.2e-06 28.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SprA-related PF12118.3 EDO17981.1 - 0.0043 16.4 28.4 0.0043 16.4 19.7 3.1 3 0 0 3 3 3 1 SprA-related family Tim54 PF11711.3 EDO17981.1 - 4.5 5.7 14.1 11 4.4 9.8 1.6 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.3 EDO17981.1 - 5.3 5.6 17.3 8.2 5.0 12.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Septin PF00735.13 EDO17982.1 - 1.5e-72 244.0 3.2 1.5e-72 244.0 2.2 2.7 2 1 0 2 2 2 1 Septin NB-ARC PF00931.17 EDO17982.1 - 0.0026 16.6 0.0 0.0065 15.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain FtsK_SpoIIIE PF01580.13 EDO17982.1 - 0.0029 17.1 0.2 0.0064 15.9 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 EDO17982.1 - 0.0045 16.8 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO17982.1 - 0.0054 16.8 0.0 0.023 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AIG1 PF04548.11 EDO17982.1 - 0.008 15.2 0.2 0.008 15.2 0.1 2.3 2 0 0 2 2 2 1 AIG1 family AAA_18 PF13238.1 EDO17982.1 - 0.013 15.8 2.7 0.089 13.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EDO17982.1 - 0.015 15.2 0.1 0.067 13.1 0.1 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF258 PF03193.11 EDO17982.1 - 0.027 13.6 0.0 0.07 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EDO17982.1 - 0.038 14.1 0.0 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 EDO17982.1 - 0.047 14.5 0.4 0.5 11.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain Synaptobrevin PF00957.16 EDO17982.1 - 0.068 12.7 1.3 0.29 10.7 0.9 2.1 1 0 0 1 1 1 0 Synaptobrevin AAA PF00004.24 EDO17982.1 - 0.076 13.2 0.3 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LST1 PF05083.8 EDO17982.1 - 0.13 12.3 0.5 0.8 9.7 0.1 2.3 2 0 0 2 2 2 0 LST-1 protein Glycoprotein_B PF00606.13 EDO17983.1 - 0.0069 14.4 0.8 0.0092 14.0 0.6 1.1 1 0 0 1 1 1 1 Herpesvirus Glycoprotein B ArsC PF03960.10 EDO17983.1 - 0.054 13.5 0.5 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 ArsC family adh_short_C2 PF13561.1 EDO17984.1 - 4.1e-27 95.4 0.0 4.9e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EDO17984.1 - 1.5e-18 67.2 0.1 3e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EDO17984.1 - 7e-06 25.8 0.0 2.7e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EDO17984.1 - 0.033 13.6 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Hom_end_hint PF05203.11 EDO17985.1 - 2e-49 168.2 0.0 2.4e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.9 EDO17985.1 - 7.6e-45 151.3 0.0 5.6e-37 126.0 0.0 2.5 2 0 0 2 2 2 2 Homing endonuclease LAGLIDADG_3 PF14528.1 EDO17985.1 - 8.7e-11 41.9 0.0 1.3e-06 28.5 0.0 3.1 2 1 0 2 2 2 2 LAGLIDADG-like domain NinE PF05322.6 EDO17985.1 - 0.023 14.4 0.1 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 NINE Protein DUF1794 PF08768.6 EDO17985.1 - 0.083 12.7 0.2 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1794) HSP70 PF00012.15 EDO17986.1 - 7.8e-236 783.6 9.8 8.7e-236 783.5 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO17986.1 - 9.5e-17 60.5 1.2 2.5e-15 55.9 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EDO17986.1 - 0.0005 19.7 0.0 0.00094 18.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2603 PF10788.4 EDO17986.1 - 0.065 12.9 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) FtsA PF14450.1 EDO17986.1 - 5 6.9 11.9 12 5.7 0.2 4.4 2 2 1 3 3 3 0 Cell division protein FtsA Y_phosphatase PF00102.22 EDO17987.1 - 6.3e-55 186.0 2.9 1.8e-54 184.5 2.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EDO17987.1 - 0.00012 21.6 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EDO17987.1 - 0.025 14.6 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EDO17987.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family SusD-like_3 PF14322.1 EDO17987.1 - 0.065 13.2 0.1 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Ost4 PF10215.4 EDO17988.1 - 1e-11 44.1 3.0 1e-11 44.1 2.1 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase VID27 PF08553.5 EDO17989.1 - 4.4e-206 686.6 17.3 5.8e-206 686.2 12.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Topo_Zn_Ribbon PF08272.6 EDO17989.1 - 0.055 12.8 0.2 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like Neugrin PF06413.6 EDO17990.1 - 4.4e-07 29.9 2.0 7.4e-07 29.2 1.4 1.5 1 1 0 1 1 1 1 Neugrin HTH_11 PF08279.7 EDO17990.1 - 0.005 16.4 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 HTH domain Sigma70_r4 PF04545.11 EDO17990.1 - 0.017 14.4 0.0 0.04 13.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.17 EDO17990.1 - 0.025 14.4 0.0 0.064 13.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix Seryl_tRNA_N PF02403.17 EDO17990.1 - 1.1 9.3 10.5 0.55 10.2 2.9 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PAPA-1 PF04795.7 EDO17992.1 - 2.8e-18 66.3 4.3 2.8e-18 66.3 3.0 3.4 3 1 0 3 3 3 1 PAPA-1-like conserved region DUF966 PF06136.8 EDO17992.1 - 0.015 14.7 19.1 0.023 14.1 13.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Plasmodium_Vir PF05795.6 EDO17992.1 - 0.19 10.8 9.4 0.29 10.2 6.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Rap1-DNA-bind PF09197.5 EDO17993.1 - 9.7e-46 154.6 12.0 5.3e-42 142.6 0.5 3.6 2 1 0 2 2 2 2 Rap1, DNA-binding Rap1_C PF11626.3 EDO17993.1 - 5.8e-26 90.2 0.0 1.4e-23 82.5 0.0 3.9 3 1 1 4 4 4 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 EDO17993.1 - 3.3e-09 36.6 0.0 4.6e-08 32.9 0.0 3.0 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.6 EDO17993.1 - 3.2e-08 33.2 0.2 0.0001 22.0 0.0 2.8 2 0 0 2 2 2 2 Rap1 Myb domain BRCT PF00533.21 EDO17993.1 - 0.002 18.2 3.5 0.0028 17.7 0.1 3.0 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_6 PF13921.1 EDO17993.1 - 0.0085 16.1 0.2 0.19 11.8 0.0 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Hpt PF01627.18 EDO17994.1 - 2.9e-14 52.8 0.1 3.8e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Hpt domain Hexokinase_2 PF03727.11 EDO17994.1 - 0.0017 17.6 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase DUF1804 PF08822.6 EDO17994.1 - 0.034 13.8 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Hydrolase_6 PF13344.1 EDO17995.1 - 1e-26 92.7 0.0 1.9e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDO17995.1 - 2.2e-14 52.9 0.0 3.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EDO17995.1 - 1.7e-12 48.2 0.0 6.4e-12 46.3 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDO17995.1 - 2.7e-05 24.4 0.1 0.22 11.7 0.0 2.7 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase DUF1947 PF09183.5 EDO17995.1 - 0.072 12.8 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Adenylsucc_synt PF00709.16 EDO17996.1 - 5.9e-165 548.9 0.0 6.7e-165 548.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase POP1 PF06978.6 EDO17997.1 - 5.1e-67 225.1 10.0 5.1e-67 225.1 6.9 2.1 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EDO17997.1 - 3.3e-35 119.7 1.1 9.1e-35 118.3 0.8 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.6 EDO17997.1 - 0.0021 18.0 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Amidohydro_1 PF01979.15 EDO17999.1 - 3.5e-46 158.3 0.0 4.2e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EDO17999.1 - 3.7e-05 23.1 0.2 0.015 14.4 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EDO17999.1 - 0.00091 19.3 0.1 0.33 10.9 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EDO17999.1 - 0.0015 18.3 0.2 0.0057 16.4 0.2 2.1 1 1 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EDO17999.1 - 0.027 13.4 0.0 0.084 11.7 0.0 1.7 1 1 0 1 1 1 0 Adenosine/AMP deaminase Ssu72 PF04722.8 EDO18000.1 - 2.8e-88 294.3 0.2 3.2e-88 294.1 0.2 1.0 1 0 0 1 1 1 1 Ssu72-like protein NYN_YacP PF05991.6 EDO18000.1 - 0.0045 16.7 0.0 0.0084 15.8 0.0 1.5 1 1 0 1 1 1 1 YacP-like NYN domain HLH PF00010.21 EDO18001.1 - 3e-12 46.0 3.3 6.6e-12 44.9 2.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FANCI_S2 PF14676.1 EDO18001.1 - 0.063 13.1 0.5 0.096 12.5 0.4 1.2 1 0 0 1 1 1 0 FANCI solenoid 2 LicD PF04991.8 EDO18002.1 - 3.8e-53 180.6 2.9 3.8e-53 180.6 2.0 2.3 3 0 0 3 3 3 1 LicD family Cpn60_TCP1 PF00118.19 EDO18003.1 - 3.7e-144 480.9 3.8 4.3e-144 480.7 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3437 PF11919.3 EDO18004.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 EDO18006.1 - 3.2e-36 123.4 0.2 1.5e-16 60.4 0.0 2.9 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EDO18006.1 - 9.5e-17 59.7 0.1 0.0019 18.4 0.0 6.1 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.17 EDO18006.1 - 1.3e-10 40.4 0.7 0.079 13.0 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 EDO18006.1 - 1.4e-07 31.8 5.2 0.0031 17.9 0.1 4.7 3 2 1 4 4 4 3 HEAT-like repeat Arm PF00514.18 EDO18006.1 - 0.0015 18.2 0.2 0.1 12.4 0.0 3.2 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat PEMT PF04191.8 EDO18007.1 - 1.4e-34 118.3 2.8 1.4e-34 118.3 1.9 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF4239 PF14023.1 EDO18007.1 - 0.046 13.0 3.0 2 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) ThiF PF00899.16 EDO18008.1 - 2.4e-52 176.3 0.1 3.5e-31 107.8 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EDO18008.1 - 1.7e-44 150.9 0.1 8.1e-44 148.7 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EDO18008.1 - 5.9e-33 112.2 0.1 5e-22 77.2 0.0 2.8 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EDO18008.1 - 4e-26 90.1 0.1 1.4e-20 72.4 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Mog1 PF04603.7 EDO18009.1 - 4.5e-22 78.5 0.4 6.1e-21 74.8 0.2 2.4 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Thr_dehydrat_C PF00585.13 EDO18009.1 - 0.048 13.2 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase Gly_transf_sug PF04488.10 EDO18010.1 - 1.9e-09 37.8 0.1 5.6e-09 36.3 0.1 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif FBP PF07299.6 EDO18010.1 - 0.0029 16.9 1.0 0.0055 16.0 0.7 1.4 1 0 0 1 1 1 1 Fibronectin-binding protein (FBP) SlyX PF04102.7 EDO18010.1 - 0.0069 16.7 2.5 0.022 15.1 0.9 2.1 2 0 0 2 2 2 1 SlyX Flavodoxin_3 PF12641.2 EDO18010.1 - 0.051 12.9 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain TMF_DNA_bd PF12329.3 EDO18010.1 - 1.7 8.5 8.7 0.24 11.2 0.4 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 EDO18010.1 - 9.9 6.1 7.2 17 5.3 0.3 2.4 1 1 1 2 2 2 0 FlxA-like protein Syja_N PF02383.13 EDO18011.1 - 5.3e-84 281.7 1.0 7.8e-84 281.1 0.7 1.3 1 0 0 1 1 1 1 SacI homology domain PUL PF08324.6 EDO18012.1 - 3e-57 193.4 3.0 4.2e-57 192.9 2.1 1.2 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 EDO18012.1 - 7.9e-45 149.2 22.0 1.7e-09 37.1 0.1 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat PFU PF09070.6 EDO18012.1 - 1.3e-43 147.7 0.1 2.7e-43 146.6 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.1 EDO18012.1 - 1.3e-06 28.1 0.8 0.28 10.9 0.0 4.6 4 1 1 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 EDO18012.1 - 0.013 13.6 1.5 1.3 7.0 0.0 3.1 2 1 0 2 2 2 0 Nucleoporin Nup120/160 HD PF01966.17 EDO18012.1 - 0.13 12.2 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 HD domain Hydantoinase_B PF02538.9 EDO18013.1 - 4.7e-218 724.6 0.0 7.9e-218 723.9 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EDO18013.1 - 6e-91 304.5 0.0 1.3e-90 303.4 0.0 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EDO18013.1 - 2.4e-55 186.7 0.1 2.1e-53 180.4 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Flocculin PF00624.13 EDO18014.1 - 4.1e-266 858.7 643.6 8.5e-13 47.9 12.8 30.0 30 1 0 30 30 30 27 Flocculin repeat ComC PF03047.9 EDO18014.1 - 2.8 7.4 4.7 0.68 9.4 0.8 1.8 2 0 0 2 2 2 0 COMC family ATE_C PF04377.10 EDO18014.1 - 5.6 7.0 42.6 32 4.6 0.2 9.3 9 0 0 9 9 9 0 Arginine-tRNA-protein transferase, C terminus DUF2140 PF09911.4 EDO18015.1 - 6.2e-24 84.1 5.5 7.7 5.6 0.0 18.1 5 5 8 22 22 22 15 Uncharacterized protein conserved in bacteria (DUF2140) DUF2140 PF09911.4 EDO18016.1 - 5.3e-20 71.3 4.9 8.6 5.4 0.0 18.0 6 5 18 27 27 27 13 Uncharacterized protein conserved in bacteria (DUF2140) TPT PF03151.11 EDO18017.1 - 9.4e-22 77.3 9.7 9.4e-22 77.3 6.7 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EDO18017.1 - 0.0001 22.3 6.1 0.0001 22.3 4.2 2.7 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EDO18017.1 - 0.00019 20.4 15.9 0.0023 16.9 11.0 1.9 1 1 0 1 1 1 1 UAA transporter family Mito_carr PF00153.22 EDO18018.1 - 3.3e-31 106.8 6.3 3.6e-12 45.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 EDO18019.1 - 9.8e-26 90.2 34.1 1.3e-19 70.1 16.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO18019.1 - 1.2e-08 33.9 34.0 7.4e-05 21.5 14.3 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter YrhC PF14143.1 EDO18019.1 - 8.2 6.4 8.8 4.8 7.2 0.1 3.4 3 0 0 3 3 3 0 YrhC-like protein DUF2034 PF10356.4 EDO18020.1 - 1.2e-51 174.5 0.1 1.4e-51 174.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EDO18020.1 - 4.8e-06 26.3 0.0 0.0086 15.8 0.0 2.5 3 0 0 3 3 3 2 Restriction endonuclease Cauli_AT PF03233.8 EDO18021.1 - 0.044 13.5 1.9 0.046 13.4 1.3 1.0 1 0 0 1 1 1 0 Aphid transmission protein XhlA PF10779.4 EDO18021.1 - 2.5 8.0 6.6 1.3 8.9 2.1 1.9 1 1 1 2 2 2 0 Haemolysin XhlA Ribonuclease_3 PF00636.21 EDO18022.1 - 8e-17 61.7 0.3 2.4e-16 60.1 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EDO18022.1 - 2.6e-14 53.3 0.0 5.1e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EDO18022.1 - 4e-05 24.0 0.0 0.00011 22.7 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif RCC1 PF00415.13 EDO18023.1 - 1.3e-22 79.7 3.7 1.8e-11 44.0 0.0 4.8 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDO18023.1 - 4.1e-13 48.5 0.7 3.3e-05 23.3 0.0 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EDO18023.1 - 3.7e-09 36.5 3.1 7.8e-08 32.2 0.1 3.3 4 0 0 4 4 4 1 BTB/POZ domain Flocculin PF00624.13 EDO18024.1 - 2e-81 267.6 348.9 4e-13 48.9 6.9 20.5 19 3 0 19 19 19 16 Flocculin repeat ATP-synt_ab PF00006.20 EDO18025.1 - 1.4e-68 230.6 0.0 2e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDO18025.1 - 1.5e-25 89.8 0.5 4.2e-25 88.4 0.3 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDO18025.1 - 5.2e-17 61.8 1.8 1.5e-16 60.3 1.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EDO18025.1 - 0.015 15.1 0.6 0.038 13.8 0.4 1.7 1 0 0 1 1 1 0 HAS barrel domain Tex_N PF09371.5 EDO18025.1 - 0.017 14.4 0.0 0.046 13.0 0.0 1.6 1 0 0 1 1 1 0 Tex-like protein N-terminal domain AAA_25 PF13481.1 EDO18025.1 - 0.078 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cyclin_N PF00134.18 EDO18026.1 - 2.1e-10 40.2 0.9 2.1e-10 40.2 0.6 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EDO18026.1 - 0.034 13.9 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Peptidase_M41 PF01434.13 EDO18027.1 - 1.4e-67 227.3 0.1 2.1e-67 226.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EDO18027.1 - 5.7e-39 133.3 0.0 1.6e-38 131.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDO18027.1 - 2.1e-05 25.3 0.1 0.00011 23.0 0.0 2.3 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 EDO18027.1 - 0.00011 21.0 0.0 0.00022 20.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EDO18027.1 - 0.00019 21.4 0.0 0.00055 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO18027.1 - 0.00021 21.4 0.8 0.024 14.7 0.1 3.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EDO18027.1 - 0.00057 19.0 0.0 0.0017 17.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDO18027.1 - 0.0014 18.3 0.0 0.005 16.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDO18027.1 - 0.0016 18.3 0.0 0.0077 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO18027.1 - 0.002 17.8 2.0 0.0072 16.0 1.4 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EDO18027.1 - 0.0061 16.8 1.2 0.012 15.8 0.0 2.2 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EDO18027.1 - 0.0069 15.8 0.2 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EDO18027.1 - 0.015 14.7 0.8 0.085 12.2 0.6 2.2 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EDO18027.1 - 0.023 13.8 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_2 PF07724.9 EDO18027.1 - 0.028 14.3 0.0 0.084 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 EDO18027.1 - 0.031 14.2 0.0 0.077 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EDO18027.1 - 0.031 13.3 0.1 0.062 12.3 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EDO18027.1 - 0.033 13.1 0.0 0.077 11.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EDO18027.1 - 0.078 12.1 0.5 0.29 10.3 0.3 1.9 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 EDO18027.1 - 0.08 12.0 0.2 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FAD_binding_3 PF01494.14 EDO18028.1 - 5.3e-18 65.2 0.0 2.7e-17 62.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EDO18028.1 - 9.5e-06 25.5 0.0 2.4e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EDO18028.1 - 3.5e-05 22.8 0.0 0.00017 20.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase ApbA PF02558.11 EDO18028.1 - 0.0003 20.2 0.0 0.00052 19.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EDO18028.1 - 0.00043 20.6 0.0 0.0024 18.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDO18028.1 - 0.0016 18.3 0.0 0.0026 17.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EDO18028.1 - 0.0018 17.1 0.0 0.0059 15.4 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase UDPG_MGDP_dh_N PF03721.9 EDO18028.1 - 0.0084 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EDO18028.1 - 0.0085 15.7 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EDO18028.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Cnd2 PF05786.9 EDO18029.1 - 2.2e-124 416.6 42.2 4.3e-124 415.6 29.3 1.4 1 1 0 1 1 1 1 Condensin complex subunit 2 Secretin_N_2 PF07655.8 EDO18029.1 - 0.016 15.5 2.1 0.016 15.5 1.5 4.0 4 0 0 4 4 4 0 Secretin N-terminal domain DTHCT PF08070.6 EDO18029.1 - 2.2 9.0 9.0 0.24 12.0 2.2 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region Rox3 PF08633.5 EDO18030.1 - 2.7e-64 217.0 2.5 3.2e-64 216.8 1.8 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit Dynamin_M PF01031.15 EDO18030.1 - 0.076 11.7 0.2 0.1 11.3 0.2 1.1 1 0 0 1 1 1 0 Dynamin central region Motile_Sperm PF00635.21 EDO18031.1 - 8e-20 70.5 0.0 1.2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Peptidase_M24 PF00557.19 EDO18032.1 - 1.3e-43 149.0 0.0 1.5e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_S21 PF01165.15 EDO18033.1 - 3.7e-13 48.6 0.8 6.2e-13 47.9 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Aa_trans PF01490.13 EDO18034.1 - 2.3e-111 372.2 24.5 2.7e-111 371.9 16.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EDO18034.1 - 2.3e-07 29.9 16.9 2.3e-07 29.9 11.7 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family SH3_1 PF00018.23 EDO18035.1 - 2.3e-10 39.7 0.2 4.2e-10 38.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO18035.1 - 5.8e-09 35.3 0.2 1.1e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDO18035.1 - 9e-07 28.2 0.0 2e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PI3_PI4_kinase PF00454.22 EDO18036.1 - 2.6e-52 177.6 0.0 1.4e-51 175.2 0.0 2.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EDO18036.1 - 9.6e-33 113.1 4.1 9.6e-33 113.1 2.9 3.6 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EDO18036.1 - 2e-10 39.9 0.0 5.6e-10 38.4 0.0 1.9 1 0 0 1 1 1 1 FATC domain Defensin_big PF14862.1 EDO18036.1 - 0.061 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Big defensin Ribosomal_L14 PF00238.14 EDO18037.1 - 3.6e-31 107.4 0.0 4e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zf-C3HC4_3 PF13920.1 EDO18038.1 - 2e-09 36.9 5.0 2.9e-09 36.4 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO18038.1 - 2.4e-09 36.6 6.2 3.7e-09 36.0 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO18038.1 - 1.5e-08 34.2 6.2 2.3e-08 33.6 4.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDO18038.1 - 7.9e-08 32.0 6.5 1.2e-07 31.4 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EDO18038.1 - 2.3e-06 27.5 7.8 3.7e-06 26.8 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO18038.1 - 2e-05 24.1 4.9 4e-05 23.2 3.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EDO18038.1 - 0.001 18.9 8.3 0.0018 18.0 5.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF2616 PF11077.3 EDO18038.1 - 0.043 13.3 0.4 0.055 12.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) zf-Apc11 PF12861.2 EDO18038.1 - 0.074 12.8 1.9 0.11 12.3 1.3 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EDO18038.1 - 1.6 8.3 6.7 19 4.9 4.9 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 EDO18038.1 - 2.3 8.1 5.1 5.3 7.0 3.6 1.6 1 1 0 1 1 1 0 FYVE zinc finger NT-C2 PF10358.4 EDO18040.1 - 3.1e-35 120.7 2.0 4.5e-35 120.2 1.4 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins PMC2NT PF08066.7 EDO18040.1 - 0.036 14.3 0.1 0.1 12.8 0.1 1.8 1 0 0 1 1 1 0 PMC2NT (NUC016) domain PH PF00169.24 EDO18041.1 - 6.1e-15 55.3 0.1 4.8e-13 49.2 0.0 3.1 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.23 EDO18041.1 - 8.5e-14 50.6 0.2 1.8e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 EDO18041.1 - 4.2e-13 48.9 0.0 8.5e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EDO18041.1 - 3.9e-10 39.9 0.4 2.1e-08 34.4 0.0 3.9 3 0 0 3 3 3 1 Pleckstrin homology domain SH3_9 PF14604.1 EDO18041.1 - 4.7e-10 38.9 0.1 8.2e-10 38.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EDO18041.1 - 2.8e-05 24.1 0.1 5.4e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 EDO18041.1 - 0.00011 21.5 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 EDO18041.1 - 0.00065 19.7 0.0 0.059 13.4 0.0 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain EMP70 PF02990.11 EDO18042.1 - 1.2e-71 241.7 18.9 1.6e-71 241.3 13.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 SK_channel PF03530.9 EDO18042.1 - 3.4 7.5 11.0 0.19 11.5 1.9 2.8 2 0 0 2 2 2 0 Calcium-activated SK potassium channel LSM PF01423.17 EDO18043.1 - 5.8e-15 54.6 0.1 1e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO18043.1 - 3.6e-05 23.6 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 EDO18043.1 - 0.041 13.7 0.2 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain Ank_2 PF12796.2 EDO18044.1 - 7.9e-10 38.9 2.2 0.00028 21.1 0.3 3.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDO18044.1 - 3.7e-08 32.7 5.7 0.00074 19.2 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EDO18044.1 - 6.7e-08 32.8 8.9 0.00091 19.6 1.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO18044.1 - 4.3e-06 26.4 5.0 0.0043 17.1 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 EDO18044.1 - 1.7e-05 24.4 0.6 1.7e-05 24.4 0.4 4.4 3 2 0 3 3 3 1 KilA-N domain Ank_5 PF13857.1 EDO18044.1 - 5.5e-05 23.2 4.5 0.0014 18.7 0.2 3.7 4 1 0 4 4 4 2 Ankyrin repeats (many copies) ALG3 PF05208.8 EDO18045.1 - 1.2e-121 406.4 29.1 1.5e-121 406.1 20.2 1.1 1 0 0 1 1 1 1 ALG3 protein LisH PF08513.6 EDO18046.1 - 3.4e-06 26.5 0.2 6.3e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 LisH WD40 PF00400.27 EDO18047.1 - 3.4e-28 96.4 12.7 1.1e-07 31.4 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 EDO18047.1 - 0.0003 19.0 0.1 0.21 9.6 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EDO18047.1 - 0.0054 16.4 0.1 3.4 7.3 0.0 3.3 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A GatB_N PF02934.10 EDO18048.1 - 6.1e-95 317.4 0.0 8.3e-95 316.9 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EDO18048.1 - 1.3e-28 99.5 0.8 2.2e-28 98.8 0.6 1.4 1 0 0 1 1 1 1 GatB domain Nucleoporin_C PF03177.9 EDO18049.1 - 5.1e-140 467.7 4.4 7e-140 467.3 3.1 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EDO18049.1 - 2.8e-115 385.4 14.3 2.8e-115 385.4 9.9 2.2 2 0 0 2 2 2 1 Nup133 N terminal like HSP70 PF00012.15 EDO18050.1 - 3.3e-268 890.5 7.9 3.8e-268 890.4 5.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO18050.1 - 8.6e-17 60.7 0.1 1.1e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EDO18050.1 - 0.00063 19.4 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EDO18050.1 - 0.0081 15.0 0.6 0.16 10.8 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Ribosomal_S8e PF01201.17 EDO18051.1 - 2.3e-50 170.1 3.2 2.6e-50 169.9 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e zf-CSL PF05207.8 EDO18052.1 - 3.2e-24 84.1 1.4 4e-24 83.8 1.0 1.1 1 0 0 1 1 1 1 CSL zinc finger ATPase-cat_bd PF12156.3 EDO18052.1 - 0.031 14.7 0.0 0.042 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Zn-ribbon_8 PF09723.5 EDO18052.1 - 0.091 12.7 1.7 0.2 11.6 1.1 1.7 1 1 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.7 EDO18052.1 - 0.41 10.0 4.0 0.17 11.1 0.9 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding UQ_con PF00179.21 EDO18053.1 - 1.4e-27 95.8 0.2 2.3e-27 95.1 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDO18053.1 - 0.0057 16.5 0.1 0.0057 16.5 0.1 1.9 2 1 0 2 2 2 1 RWD domain Prok-E2_B PF14461.1 EDO18053.1 - 0.0076 16.0 0.0 0.023 14.4 0.0 1.7 1 1 0 1 1 1 1 Prokaryotic E2 family B GET2 PF08690.5 EDO18053.1 - 0.26 10.4 0.0 0.26 10.4 0.0 2.0 1 1 1 2 2 2 0 GET complex subunit GET2 Pribosyltran_N PF13793.1 EDO18054.1 - 5.7e-44 148.5 0.2 2.4e-41 140.1 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EDO18054.1 - 6.4e-35 120.5 1.7 2.6e-29 102.2 0.4 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EDO18054.1 - 1.2e-12 47.6 1.4 3e-12 46.3 0.2 2.1 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDO18054.1 - 0.0017 17.6 0.3 0.0032 16.6 0.1 1.6 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase UCH PF00443.24 EDO18055.1 - 8.1e-73 244.8 2.7 2.3e-72 243.3 1.9 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO18055.1 - 1.9e-28 99.7 0.9 2.7e-20 73.0 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Adap_comp_sub PF00928.16 EDO18057.1 - 3e-78 262.5 0.7 4.5e-78 261.9 0.5 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pribosyl_synth PF14572.1 EDO18058.1 - 3.1e-41 141.1 0.1 5.2e-41 140.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EDO18058.1 - 2.2e-36 124.1 0.0 6.9e-35 119.2 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EDO18058.1 - 2.8e-13 49.6 0.3 7.4e-13 48.3 0.2 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDO18058.1 - 0.019 14.1 0.1 0.037 13.2 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Pkinase PF00069.20 EDO18059.1 - 8.6e-53 179.1 0.0 1.8e-52 178.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18059.1 - 3.8e-18 65.5 0.0 6.3e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Innate_immun PF12782.2 EDO18059.1 - 0.042 13.0 12.2 0.072 12.3 8.4 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family NicO PF03824.11 EDO18059.1 - 4.1 6.6 7.5 6.4 5.9 5.2 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF21 PF01595.15 EDO18060.1 - 1.6e-34 118.7 0.4 9e-34 116.3 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF21 CBS PF00571.23 EDO18060.1 - 0.0055 16.4 0.0 3.5 7.4 0.0 2.9 2 0 0 2 2 2 2 CBS domain NAD_Gly3P_dh_N PF01210.18 EDO18061.1 - 1e-50 171.4 0.0 1.6e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EDO18061.1 - 1.2e-45 154.8 0.3 2.1e-45 154.0 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EDO18061.1 - 0.004 17.5 0.0 1.4 9.3 0.0 2.8 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent ComX PF05952.7 EDO18061.1 - 0.047 13.2 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Bacillus competence pheromone ComX PDH PF02153.12 EDO18061.1 - 0.11 11.3 0.0 8 5.2 0.0 2.2 2 0 0 2 2 2 0 Prephenate dehydrogenase Peptidase_M49 PF03571.10 EDO18062.1 - 1.6e-235 782.4 0.5 2.7e-235 781.6 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M49 His_Phos_1 PF00300.17 EDO18063.1 - 2.6e-41 141.3 0.0 5e-41 140.4 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2962 PF11176.3 EDO18063.1 - 0.0063 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Phos_pyr_kin PF08543.7 EDO18064.1 - 1.2e-80 270.3 1.3 1.8e-80 269.6 0.9 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EDO18064.1 - 3e-59 200.3 0.9 4.1e-59 199.8 0.6 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EDO18064.1 - 8.1e-07 28.4 0.0 1.3e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Oxysterol_BP PF01237.13 EDO18065.1 - 7.6e-133 442.3 0.3 7.6e-133 442.3 0.2 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.1 EDO18065.1 - 7e-16 57.8 1.2 1.3e-06 28.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO18065.1 - 1.4e-15 57.3 0.2 1.8e-09 37.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDO18065.1 - 2.2e-12 46.1 0.4 0.00061 19.4 0.1 3.8 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EDO18065.1 - 7.1e-12 45.4 0.2 5.1e-05 23.6 0.1 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO18065.1 - 9.5e-11 40.8 0.1 0.0042 17.1 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.24 EDO18065.1 - 2.6e-08 33.9 0.5 9e-08 32.2 0.3 2.0 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EDO18065.1 - 4.9e-08 32.9 1.2 1.6e-07 31.2 0.9 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EDO18065.1 - 0.0022 18.2 4.4 0.0022 18.2 3.0 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain Carn_acyltransf PF00755.15 EDO18066.1 - 4e-173 576.6 3.0 4.8e-173 576.4 2.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Rad21_Rec8_N PF04825.8 EDO18067.1 - 1.2e-25 89.6 0.1 2.7e-25 88.4 0.1 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EDO18067.1 - 1.4e-10 40.2 0.0 3.4e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein HMG_box PF00505.14 EDO18070.1 - 4.5e-16 58.8 5.2 7.7e-16 58.1 1.0 2.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO18070.1 - 1.1e-15 57.7 0.8 4.4e-15 55.8 0.6 2.1 1 0 0 1 1 1 1 HMG-box domain DUF155 PF02582.9 EDO18071.1 - 4.7e-62 208.9 2.3 7e-62 208.4 1.6 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 EDO18071.1 - 0.027 14.6 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF77 PF01910.12 EDO18072.1 - 6.4e-24 83.4 0.0 7.1e-24 83.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 SGS PF05002.10 EDO18072.1 - 0.15 11.8 0.1 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 SGS domain Trehalase PF01204.13 EDO18073.1 - 1e-188 628.2 0.1 1.3e-188 627.8 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EDO18073.1 - 1.6e-16 59.2 0.4 2.9e-16 58.4 0.3 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ran_BP1 PF00638.13 EDO18074.1 - 2.6e-55 185.7 1.0 3.6e-55 185.2 0.7 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EDO18074.1 - 1.7e-05 24.4 0.5 0.00018 21.2 0.4 2.1 1 1 0 1 1 1 1 WH1 domain BRAP2 PF07576.7 EDO18074.1 - 0.064 12.8 0.2 0.22 11.1 0.0 1.9 2 0 0 2 2 2 0 BRCA1-associated protein 2 Mannosyl_trans2 PF04188.8 EDO18075.1 - 1.4e-92 310.9 44.9 2.6e-90 303.4 31.1 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) RCR PF12273.3 EDO18076.1 - 3e-40 137.7 0.0 3e-40 137.7 0.0 2.0 1 1 1 2 2 2 1 Chitin synthesis regulation, resistance to Congo red She9_MDM33 PF05546.6 EDO18076.1 - 0.51 9.8 4.2 8.6 5.8 0.3 2.1 2 0 0 2 2 2 0 She9 / Mdm33 family Aldedh PF00171.17 EDO18077.1 - 1.9e-155 517.7 0.0 2.1e-155 517.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EDO18077.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Maf1 PF09174.5 EDO18078.1 - 6.9e-54 182.4 9.6 3.5e-50 170.3 6.6 2.5 1 1 0 1 1 1 1 Maf1 regulator CRAM_rpt PF07016.6 EDO18078.1 - 1.8 7.9 6.9 0.28 10.5 1.4 2.2 2 0 0 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor Tcp11 PF05794.8 EDO18079.1 - 7.1e-158 525.9 6.2 8.8e-158 525.6 4.3 1.1 1 0 0 1 1 1 1 T-complex protein 11 PRAI PF00697.17 EDO18080.1 - 5.5e-56 189.2 0.0 6.7e-56 188.9 0.0 1.1 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase zf-Apc11 PF12861.2 EDO18081.1 - 1.6e-42 143.2 6.8 2.4e-42 142.6 4.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EDO18081.1 - 2.5e-29 101.1 8.4 5e-29 100.2 5.8 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EDO18081.1 - 2.8e-06 27.0 19.0 6.6e-06 25.8 11.9 2.6 1 1 1 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EDO18081.1 - 0.0012 18.5 12.4 0.013 15.2 9.0 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO18081.1 - 0.0022 17.6 12.5 0.01 15.4 8.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO18081.1 - 0.011 15.6 13.3 0.14 12.2 9.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO18081.1 - 0.015 15.1 2.3 0.015 15.1 1.6 2.7 2 2 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EDO18081.1 - 0.019 14.8 13.4 0.15 12.0 9.3 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EDO18081.1 - 0.02 14.4 1.2 0.02 14.4 0.8 3.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF919 PF06034.6 EDO18081.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) zf-C3HC4_3 PF13920.1 EDO18081.1 - 0.084 12.5 12.5 3.4 7.4 8.8 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-HIT PF04438.11 EDO18081.1 - 0.23 11.1 7.7 0.12 12.0 2.3 2.2 2 0 0 2 2 2 0 HIT zinc finger zf-HC5HC2H_2 PF13832.1 EDO18081.1 - 0.93 9.5 7.3 0.5 10.3 3.4 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING-like PF08746.6 EDO18081.1 - 1.1 9.3 11.5 1.7 8.7 6.6 2.3 1 1 1 2 2 2 0 RING-like domain zf-HC5HC2H PF13771.1 EDO18081.1 - 1.5 9.0 7.7 5.8 7.1 5.5 1.9 1 1 1 2 2 2 0 PHD-like zinc-binding domain DZR PF12773.2 EDO18081.1 - 2.2 8.1 10.0 14 5.6 4.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon Glutaredoxin PF00462.19 EDO18082.1 - 1.6e-11 44.0 0.0 3.1e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EDO18082.1 - 0.0019 18.3 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_3 PF13192.1 EDO18082.1 - 0.0021 17.7 0.0 0.018 14.8 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain DUF836 PF05768.9 EDO18082.1 - 0.011 15.9 0.0 0.029 14.6 0.0 1.8 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Thioredoxin_7 PF13899.1 EDO18082.1 - 0.023 14.7 0.1 0.066 13.2 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO18082.1 - 0.028 14.6 2.9 0.052 13.7 0.1 2.3 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EDO18082.1 - 0.035 13.6 0.0 0.066 12.7 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin Thioredoxin PF00085.15 EDO18082.1 - 0.047 13.3 0.1 0.14 11.8 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.1 EDO18082.1 - 0.24 11.4 4.3 5.1 7.0 0.0 2.8 2 1 1 3 3 3 0 Thioredoxin Mannosyl_trans3 PF11051.3 EDO18083.1 - 2.2e-86 289.5 0.0 3.4e-86 288.9 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Myc_N PF01056.13 EDO18083.1 - 0.012 14.7 1.6 0.02 14.0 1.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Shufflon_N PF04917.7 EDO18083.1 - 0.018 14.1 0.1 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial shufflon protein, N-terminal constant region DUF1510 PF07423.6 EDO18083.1 - 0.03 13.7 1.1 0.049 12.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Flocculin PF00624.13 EDO18083.1 - 3.6 7.5 8.2 7.3 6.5 5.7 1.5 1 0 0 1 1 1 0 Flocculin repeat NPR2 PF06218.6 EDO18085.1 - 7.8e-180 598.1 9.8 7.8e-180 598.1 6.8 1.9 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Kinesin PF00225.18 EDO18086.1 - 1.1e-67 228.1 4.6 1.5e-38 132.3 1.7 4.0 4 1 1 5 5 5 2 Kinesin motor domain PAZ_siRNAbind PF12212.3 EDO18086.1 - 0.0079 15.7 1.6 0.0079 15.7 1.1 3.5 3 0 0 3 3 3 1 Piwi/Argonaute/Zwille siRNA-binding domain AAA_16 PF13191.1 EDO18086.1 - 0.016 15.1 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain Barstar PF01337.13 EDO18086.1 - 0.034 13.9 0.9 0.35 10.7 0.1 3.0 2 0 0 2 2 2 0 Barstar (barnase inhibitor) Fcf1 PF04900.7 EDO18087.1 - 8.1e-33 112.5 0.9 8.1e-33 112.5 0.6 2.0 2 0 0 2 2 2 1 Fcf1 Hid1 PF12722.2 EDO18087.1 - 9.5 3.7 12.1 12 3.4 8.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_S8 PF00082.17 EDO18088.1 - 2.5e-49 167.9 9.6 3.5e-49 167.4 6.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EDO18088.1 - 3.7e-09 37.0 0.0 8.3e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Lyase_1 PF00206.15 EDO18089.1 - 1e-116 389.5 0.1 1.3e-116 389.1 0.1 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EDO18089.1 - 2.3e-25 88.3 0.1 5.8e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Kelch_3 PF13415.1 EDO18090.1 - 7.2e-32 108.8 3.7 6.8e-09 35.6 0.0 7.1 7 0 0 7 7 7 3 Galactose oxidase, central domain DUF4110 PF13422.1 EDO18090.1 - 1.9e-28 98.1 0.1 1.9e-28 98.1 0.0 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 EDO18090.1 - 1.9e-27 94.7 8.1 2.6e-05 23.8 0.0 6.9 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EDO18090.1 - 3.2e-20 71.3 10.6 3.8e-05 23.6 0.2 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EDO18090.1 - 1.3e-11 44.2 1.6 0.23 11.4 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EDO18090.1 - 1.3e-10 40.6 16.1 0.0077 15.7 0.1 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EDO18090.1 - 3.9e-05 23.2 12.9 0.16 11.7 0.0 6.0 6 0 0 6 6 6 2 Kelch motif Nop14 PF04147.7 EDO18090.1 - 5.4 4.8 41.7 0.23 9.3 7.7 3.0 3 0 0 3 3 3 0 Nop14-like family WD40 PF00400.27 EDO18091.1 - 2.2e-28 97.0 3.2 2.3e-09 36.7 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EDO18091.1 - 6e-24 83.7 0.8 9.4e-24 83.1 0.1 1.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Cut8_M PF14483.1 EDO18092.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Cut8 dimerisation domain DNA_pol_phi PF04931.8 EDO18093.1 - 2.3e-129 432.4 37.9 2.9e-129 432.1 26.2 1.1 1 0 0 1 1 1 1 DNA polymerase phi CM_2 PF01817.16 EDO18093.1 - 0.0096 15.9 2.3 0.48 10.5 0.0 3.7 3 0 0 3 3 3 1 Chorismate mutase type II ATP-synt_Eps PF04627.8 EDO18095.1 - 2.6e-21 74.8 1.1 2.9e-21 74.7 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain ABC_membrane PF00664.18 EDO18096.1 - 2.6e-53 181.2 6.7 3.5e-53 180.7 4.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EDO18096.1 - 2.2e-34 118.6 0.6 8.7e-34 116.7 0.0 2.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EDO18096.1 - 5.7e-05 22.4 0.0 0.0049 16.1 0.0 2.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDO18096.1 - 0.00013 22.0 0.6 0.001 19.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EDO18096.1 - 0.00021 20.7 0.0 0.024 14.0 0.0 3.0 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_21 PF13304.1 EDO18096.1 - 0.00026 21.0 0.6 0.76 9.6 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_17 PF13207.1 EDO18096.1 - 0.00082 20.1 0.0 0.002 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDO18096.1 - 0.0022 17.4 0.0 0.0072 15.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EDO18096.1 - 0.003 16.7 0.0 0.0074 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDO18096.1 - 0.0049 17.0 1.8 0.035 14.2 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_10 PF12846.2 EDO18096.1 - 0.005 16.3 0.2 0.4 10.0 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain AAA PF00004.24 EDO18096.1 - 0.01 16.0 0.1 0.097 12.8 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO18096.1 - 0.019 14.6 0.0 0.12 12.1 0.0 2.5 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NOGCT PF08155.6 EDO18096.1 - 0.068 12.8 0.3 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 NOGCT (NUC087) domain AAA_25 PF13481.1 EDO18096.1 - 0.17 11.3 0.0 0.98 8.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EDO18096.1 - 0.51 10.6 0.0 0.51 10.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.1 EDO18096.1 - 0.77 10.0 3.1 0.95 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain CFC PF09443.5 EDO18099.1 - 0.04 13.5 4.5 0.04 13.5 3.1 2.2 1 1 1 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) Synapsin_N PF10581.4 EDO18099.1 - 0.071 12.9 0.6 0.17 11.7 0.4 1.6 1 0 0 1 1 1 0 Synapsin N-terminal Retrotrans_gag PF03732.12 EDO18100.1 - 6e-08 32.6 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EDO18100.1 - 1.8e-05 24.4 3.0 1.8e-05 24.4 2.1 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.1 EDO18100.1 - 0.079 12.6 1.8 0.15 11.7 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 EDO18101.1 - 2.4e-28 98.9 0.2 4.4e-28 98.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO18101.1 - 1.4e-17 63.8 0.0 3.5e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 EDO18101.1 - 0.0018 17.6 0.1 0.0051 16.1 0.1 1.8 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVT_1 PF00078.22 EDO18103.1 - 1.3e-16 60.6 0.5 4.9e-15 55.4 0.4 2.8 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EDO18103.1 - 3.1e-15 56.3 0.0 2.3e-14 53.5 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain RVT_3 PF13456.1 EDO18103.1 - 0.0068 16.1 0.0 0.03 14.0 0.0 2.3 1 0 0 1 1 1 1 Reverse transcriptase-like Asp_protease_2 PF13650.1 EDO18103.1 - 0.029 14.8 0.0 1.5 9.3 0.0 2.9 2 0 0 2 2 2 0 Aspartyl protease ATP-synt_S1 PF05827.7 EDO18104.1 - 1.3e-57 195.2 0.4 1.8e-57 194.7 0.3 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PPR PF01535.15 EDO18105.1 - 0.2 11.7 1.2 1.6 8.9 0.0 3.0 4 0 0 4 4 4 0 PPR repeat Pkinase PF00069.20 EDO18106.1 - 7.2e-71 238.3 0.0 1.4e-70 237.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18106.1 - 1.2e-50 171.9 0.0 1.9e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO18106.1 - 5e-07 28.9 0.0 3.2e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDO18106.1 - 0.018 14.7 0.0 0.35 10.5 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EDO18106.1 - 0.095 11.7 0.0 2.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4240 PF14024.1 EDO18107.1 - 0.022 14.6 0.4 0.049 13.4 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) TRCF PF03461.10 EDO18107.1 - 0.06 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 TRCF domain PQ-loop PF04193.9 EDO18108.1 - 3.2e-33 113.0 13.3 1.1e-17 63.2 1.3 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EDO18108.1 - 0.46 10.3 16.4 0.31 10.9 1.3 3.9 2 2 1 3 3 3 0 Sugar efflux transporter for intercellular exchange ER_lumen_recept PF00810.13 EDO18108.1 - 1.2 9.6 12.7 0.32 11.4 0.5 3.1 1 1 2 3 3 3 0 ER lumen protein retaining receptor Pyr_redox_2 PF07992.9 EDO18109.1 - 3.7e-29 102.0 0.0 7.4e-29 101.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO18109.1 - 3.3e-17 62.6 0.1 3.7e-15 56.0 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO18109.1 - 5.5e-10 39.6 0.0 2.4e-07 31.0 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDO18109.1 - 0.00035 19.5 5.3 1.1 8.0 0.1 4.4 2 2 1 5 5 5 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EDO18109.1 - 0.00044 20.4 0.0 0.038 14.2 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EDO18109.1 - 0.0028 17.6 0.0 0.27 11.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EDO18109.1 - 0.0058 15.5 0.0 0.71 8.7 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EDO18109.1 - 0.012 15.6 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EDO18109.1 - 0.02 13.3 0.2 6.5 5.1 0.0 3.1 3 1 1 4 4 4 0 HI0933-like protein FAD_binding_2 PF00890.19 EDO18109.1 - 0.025 13.4 0.5 3 6.5 0.1 2.6 2 1 1 3 3 3 0 FAD binding domain Thi4 PF01946.12 EDO18109.1 - 0.026 13.5 0.0 0.23 10.5 0.0 2.2 2 0 0 2 2 2 0 Thi4 family DAO PF01266.19 EDO18109.1 - 0.078 11.8 0.1 24 3.6 0.1 2.9 2 1 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDO18109.1 - 0.099 11.6 0.0 8.3 5.3 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Glycos_transf_3 PF00591.16 EDO18110.1 - 1.6e-78 263.6 0.0 2.1e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EDO18110.1 - 1.1e-11 44.1 0.0 2.5e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain ATG16 PF08614.6 EDO18111.1 - 0.0012 18.6 16.2 0.0012 18.6 11.2 7.9 1 1 6 8 8 8 1 Autophagy protein 16 (ATG16) IncA PF04156.9 EDO18111.1 - 0.0059 16.2 7.0 0.0059 16.2 4.9 8.3 1 1 4 5 5 5 2 IncA protein Calici_MSP PF05752.6 EDO18111.1 - 0.0066 16.0 7.7 0.041 13.4 0.4 3.3 2 0 0 2 2 2 2 Calicivirus minor structural protein NPV_P10 PF05531.7 EDO18111.1 - 0.0085 16.3 2.3 0.0085 16.3 1.6 9.3 3 2 4 7 7 7 2 Nucleopolyhedrovirus P10 protein DUF2365 PF10157.4 EDO18112.1 - 0.0016 18.3 0.8 0.002 18.0 0.6 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) DUF1474 PF07342.6 EDO18112.1 - 0.048 13.8 2.8 0.069 13.3 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1474) DUF3641 PF12345.3 EDO18112.1 - 0.059 13.2 1.1 2.6 7.8 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3641) AAA_32 PF13654.1 EDO18112.1 - 0.09 11.4 0.4 0.094 11.3 0.3 1.1 1 0 0 1 1 1 0 AAA domain UPF0184 PF03670.8 EDO18112.1 - 0.69 10.1 5.3 0.63 10.2 0.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) VHS PF00790.14 EDO18113.1 - 3.2e-47 159.7 0.3 2e-46 157.1 0.0 2.3 2 1 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 EDO18113.1 - 3.7e-22 78.8 1.5 6.1e-22 78.1 1.1 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 EDO18113.1 - 2.1e-15 56.5 4.6 7.4e-15 54.7 3.2 2.0 1 0 0 1 1 1 1 GAT domain PrkA PF06798.7 EDO18113.1 - 0.0072 15.6 0.6 0.76 9.0 0.0 2.3 2 0 0 2 2 2 2 PrkA serine protein kinase C-terminal domain Latarcin PF10279.4 EDO18113.1 - 0.05 13.8 4.2 0.14 12.3 2.9 1.8 1 0 0 1 1 1 0 Latarcin precursor DUF4510 PF14971.1 EDO18113.1 - 0.072 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) HSA PF07529.8 EDO18114.1 - 1.7e-18 66.1 0.1 1.7e-18 66.1 0.0 4.0 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 EDO18114.1 - 8e-09 35.4 0.3 4.4e-08 33.1 0.2 2.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4175 PF13779.1 EDO18114.1 - 0.5 7.9 49.5 0.014 13.1 29.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) BCIP PF13862.1 EDO18115.1 - 6e-49 166.2 1.4 8e-49 165.7 0.9 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein EMP24_GP25L PF01105.19 EDO18116.1 - 2.8e-33 115.1 1.5 3.4e-33 114.8 1.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ThiF PF00899.16 EDO18117.1 - 2.1e-42 144.1 0.0 3.7e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EDO18117.1 - 2.3e-25 87.9 0.3 3.8e-25 87.2 0.2 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EDO18117.1 - 3.7e-14 53.0 0.0 6.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EDO18117.1 - 0.0012 18.9 0.1 0.0037 17.3 0.0 1.9 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HALZ PF02183.13 EDO18117.1 - 0.1 12.3 2.1 0.32 10.7 1.5 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper DAO PF01266.19 EDO18117.1 - 0.12 11.1 0.3 0.18 10.6 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase WD40 PF00400.27 EDO18118.1 - 0.0027 17.5 6.7 0.73 9.8 0.3 5.0 4 0 0 4 4 4 1 WD domain, G-beta repeat AT_hook PF02178.14 EDO18118.1 - 0.0087 15.6 2.6 0.023 14.2 1.8 1.8 1 0 0 1 1 1 1 AT hook motif Kri1 PF05178.7 EDO18118.1 - 1.2 9.4 6.5 0.84 9.9 1.4 2.3 1 1 1 2 2 2 0 KRI1-like family Cys_Met_Meta_PP PF01053.15 EDO18119.1 - 2.1e-66 223.8 0.0 6.6e-66 222.1 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EDO18119.1 - 3.8e-07 29.1 0.0 5.9e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EDO18119.1 - 0.011 14.7 0.0 0.014 14.3 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II FBD PF08387.5 EDO18119.1 - 0.099 12.1 0.1 0.31 10.5 0.1 1.8 1 0 0 1 1 1 0 FBD Lectin_leg-like PF03388.8 EDO18120.1 - 9.5e-11 41.2 0.1 3.4e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Legume-like lectin family Lectin_legB PF00139.14 EDO18120.1 - 0.013 14.9 1.0 0.17 11.2 0.1 2.8 3 1 0 3 3 3 0 Legume lectin domain NAP PF00956.13 EDO18123.1 - 1.9e-78 262.9 13.1 1.9e-78 262.9 9.1 2.3 3 0 0 3 3 3 1 Nucleosome assembly protein (NAP) Alb1 PF09135.6 EDO18124.1 - 1e-20 74.4 10.1 1e-20 74.4 7.0 1.6 1 1 0 1 1 1 1 Alb1 DUF2578 PF10843.3 EDO18124.1 - 0.086 12.5 0.9 0.12 12.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2578) DUF2413 PF10310.4 EDO18125.1 - 5.7e-128 427.4 35.9 6.6e-128 427.2 24.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) DUF3755 PF12579.3 EDO18125.1 - 0.054 12.8 0.1 0.17 11.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) Neur_chan_memb PF02932.11 EDO18125.1 - 1.4 8.7 11.6 3.2 7.5 0.1 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Senescence_reg PF04520.8 EDO18125.1 - 1.6 9.1 22.2 1.4 9.4 0.5 3.5 3 0 0 3 3 3 0 Senescence regulator Ndc1_Nup PF09531.5 EDO18125.1 - 4.8 5.4 20.2 1.3 7.3 7.5 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup LSM PF01423.17 EDO18126.1 - 2.5e-13 49.3 0.1 4.1e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 LSM domain EcoRI_methylase PF13651.1 EDO18126.1 - 0.029 13.4 0.1 0.037 13.1 0.1 1.1 1 0 0 1 1 1 0 Adenine-specific methyltransferase EcoRI PUF PF00806.14 EDO18126.1 - 0.085 12.3 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat GCD14 PF08704.5 EDO18127.1 - 5.1e-77 258.7 0.0 8e-76 254.7 0.0 2.1 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EDO18127.1 - 0.00076 20.0 0.0 0.0014 19.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EDO18127.1 - 0.0011 18.1 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF3748 PF12566.3 EDO18127.1 - 0.0016 18.3 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3748) Methyltransf_26 PF13659.1 EDO18127.1 - 0.0092 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Gcd10p PF04189.8 EDO18127.1 - 0.012 14.7 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Gcd10p family Methyltransf_23 PF13489.1 EDO18127.1 - 0.027 14.1 0.1 0.056 13.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 EDO18128.1 - 1.1e-55 188.5 0.0 1.7e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18128.1 - 7.6e-37 126.7 0.0 1.1e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO18128.1 - 8.1e-06 24.9 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TrkH PF02386.11 EDO18129.1 - 6.9e-124 412.9 20.9 1.6e-122 408.5 8.5 2.1 2 0 0 2 2 2 2 Cation transport protein GPW_gp25 PF04965.9 EDO18129.1 - 0.079 12.5 0.0 17 5.0 0.0 2.5 2 0 0 2 2 2 0 Gene 25-like lysozyme DUF1938 PF09153.5 EDO18129.1 - 0.12 12.1 0.9 2.7 7.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1938) Snf7 PF03357.16 EDO18130.1 - 7.8e-16 57.9 20.2 1.2e-15 57.3 14.0 1.2 1 0 0 1 1 1 1 Snf7 Baculo_PEP_C PF04513.7 EDO18130.1 - 0.36 10.6 6.3 0.18 11.6 0.8 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GrpE PF01025.14 EDO18130.1 - 0.47 9.9 14.3 0.032 13.7 6.0 1.8 1 1 1 2 2 2 0 GrpE DUF3385 PF11865.3 EDO18130.1 - 1.9 8.4 7.7 21 5.0 3.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) Fzo_mitofusin PF04799.8 EDO18130.1 - 3.6 6.9 12.5 3.1 7.1 3.4 2.2 1 1 1 2 2 2 0 fzo-like conserved region TarH PF02203.10 EDO18130.1 - 4.3 7.1 11.9 0.63 9.8 0.6 2.4 1 1 1 2 2 2 0 Tar ligand binding domain homologue CorA PF01544.13 EDO18130.1 - 5.5 5.9 7.0 2.9 6.8 2.0 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Cpn60_TCP1 PF00118.19 EDO18131.1 - 1.6e-145 485.4 7.7 1.8e-145 485.2 5.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_U59 PF04529.7 EDO18131.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus U59 protein WD40 PF00400.27 EDO18132.1 - 7e-38 127.1 18.4 3.7e-08 32.9 1.1 7.3 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EDO18132.1 - 2.2e-06 26.1 10.5 0.00031 19.0 0.2 4.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF3249 PF11615.3 EDO18132.1 - 0.00012 21.6 1.3 0.36 10.5 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3249) Mdv1 PF11542.3 EDO18132.1 - 0.016 15.1 0.4 0.016 15.1 0.3 2.3 2 0 0 2 2 2 0 Mitochondrial division protein 1 DASH_Spc34 PF08657.5 EDO18133.1 - 2.6e-68 230.5 11.1 3e-68 230.3 7.7 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 DUF217 PF02697.9 EDO18133.1 - 0.032 14.4 6.6 11 6.2 0.1 4.1 4 0 0 4 4 4 0 Uncharacterized ACR, COG1753 Occludin_ELL PF07303.8 EDO18133.1 - 0.038 14.7 5.2 0.038 14.7 3.6 2.4 2 1 0 2 2 2 0 Occludin homology domain PaaX_C PF08223.6 EDO18133.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Peptidase_M22 PF00814.20 EDO18134.1 - 1e-83 280.9 0.0 1.2e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 EDO18134.1 - 0.0028 16.8 0.0 0.0036 16.4 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase HECT PF00632.20 EDO18135.1 - 1.4e-90 303.6 0.0 2.1e-90 303.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EDO18135.1 - 5.8e-34 115.5 19.7 6.8e-11 41.8 1.0 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EDO18135.1 - 3.7e-15 55.5 0.1 1.2e-14 53.8 0.1 1.9 1 0 0 1 1 1 1 C2 domain CDC27 PF09507.5 EDO18135.1 - 1 8.4 11.4 1.5 7.9 7.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 zf-C2H2 PF00096.21 EDO18136.1 - 2.9e-12 46.1 17.9 2.1e-06 27.6 2.2 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO18136.1 - 1.6e-09 37.3 15.0 0.00012 22.1 1.2 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO18136.1 - 5.4e-08 32.7 17.2 8.6e-06 25.7 2.9 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDO18136.1 - 8e-08 32.2 10.3 0.00034 20.6 1.0 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO18136.1 - 4e-06 26.8 8.7 0.0057 16.8 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EDO18136.1 - 0.0048 16.9 5.2 0.0083 16.2 3.6 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EDO18136.1 - 0.061 13.2 7.3 0.16 11.8 1.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EDO18136.1 - 1.4 8.6 10.0 1.5 8.6 2.0 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EDO18136.1 - 1.6 8.5 16.8 0.086 12.6 1.6 2.7 2 1 1 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.2 EDO18136.1 - 3.9 7.6 12.9 4.6 7.4 1.5 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Kelch_6 PF13964.1 EDO18137.1 - 3.3e-14 52.3 1.3 3.1e-07 30.2 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 EDO18137.1 - 2e-10 40.0 1.4 0.00029 20.3 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EDO18137.1 - 1.2e-09 37.7 3.3 0.00041 20.0 0.0 5.8 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EDO18137.1 - 1.8e-09 37.5 0.8 0.055 13.6 0.0 6.5 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EDO18137.1 - 2e-08 33.6 0.2 0.0013 18.3 0.0 3.7 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 EDO18137.1 - 0.00057 19.7 0.0 0.017 15.0 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Yip1 PF04893.12 EDO18138.1 - 4.1e-11 42.6 9.1 5.9e-11 42.1 6.3 1.3 1 0 0 1 1 1 1 Yip1 domain W2 PF02020.13 EDO18139.1 - 1.1e-16 60.5 3.6 3.8e-16 58.8 2.5 2.1 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.18 EDO18139.1 - 1.7e-09 37.3 0.0 4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EDO18139.1 - 3.6e-09 35.7 22.9 0.00033 20.0 2.5 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EDO18139.1 - 0.0008 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 EDO18139.1 - 0.075 11.5 5.3 0.57 8.6 0.3 2.3 1 1 1 2 2 2 0 L-fucokinase Cpn60_TCP1 PF00118.19 EDO18140.1 - 9.4e-144 479.6 14.9 1.1e-143 479.4 10.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans_2 PF11951.3 EDO18141.1 - 3.2e-09 35.8 0.2 3.2e-09 35.8 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO18141.1 - 2.5e-06 27.3 13.9 4.1e-06 26.5 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VID27 PF08553.5 EDO18141.1 - 0.47 8.6 10.5 0.74 7.9 7.3 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2457 PF10446.4 EDO18141.1 - 1.9 7.1 22.4 0.24 10.1 11.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EDO18141.1 - 2 7.8 17.2 4.6 6.7 11.9 1.5 1 0 0 1 1 1 0 Nucleoplasmin S-antigen PF05756.6 EDO18141.1 - 3 7.8 10.1 11 6.1 7.0 2.0 1 0 0 1 1 1 0 S-antigen protein Svf1 PF08622.5 EDO18142.1 - 3.2e-105 351.7 0.6 3.8e-105 351.4 0.5 1.1 1 0 0 1 1 1 1 Svf1-like Peptidase_C25_C PF03785.9 EDO18143.1 - 0.00033 20.3 0.5 0.00038 20.1 0.4 1.1 1 0 0 1 1 1 1 Peptidase family C25, C terminal ig-like domain DUF3827 PF12877.2 EDO18144.1 - 0.14 10.2 12.2 0.22 9.6 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Pap_E4 PF02711.9 EDO18144.1 - 0.51 11.1 3.7 1 10.2 2.6 1.5 1 0 0 1 1 1 0 E4 protein SR-25 PF10500.4 EDO18144.1 - 1.2 8.5 22.3 1.4 8.2 15.4 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1399 PF07173.7 EDO18144.1 - 1.3 9.3 5.2 1.6 9.0 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1399) Ndc1_Nup PF09531.5 EDO18144.1 - 2.6 6.3 5.6 3.2 6.0 3.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LRR19-TM PF15176.1 EDO18144.1 - 4.6 6.9 6.1 11 5.7 1.6 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Histone PF00125.19 EDO18145.1 - 3.1e-22 78.4 0.3 4.2e-22 78.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDO18145.1 - 8.6e-07 28.9 0.1 1.8e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EDO18145.1 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EDO18146.1 - 6.3e-26 90.2 0.0 8.8e-26 89.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDO18146.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ADK PF00406.17 EDO18147.1 - 4e-60 202.0 0.0 4.8e-60 201.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EDO18147.1 - 5e-15 54.8 0.0 1.5e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EDO18147.1 - 4.2e-09 36.4 0.0 9.6e-09 35.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO18147.1 - 4e-06 27.6 0.0 7.1e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO18147.1 - 0.00093 19.5 0.0 0.0021 18.3 0.0 1.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EDO18147.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin AAA PF00004.24 EDO18147.1 - 0.15 12.2 0.1 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3767 PF12597.3 EDO18148.1 - 2.3e-44 149.8 0.3 3.6e-44 149.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) YrhK PF14145.1 EDO18148.1 - 0.0011 18.5 1.2 0.0017 17.9 0.8 1.2 1 0 0 1 1 1 1 YrhK-like protein Aminotran_1_2 PF00155.16 EDO18149.1 - 2.4e-73 247.1 0.0 3.1e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EDO18149.1 - 4.1e-07 28.6 0.0 6.9e-07 27.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EDO18149.1 - 1.1e-05 24.3 0.2 4.2e-05 22.4 0.1 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Aconitase PF00330.15 EDO18150.1 - 6.2e-74 249.1 0.3 1.5e-70 238.0 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDO18150.1 - 1.3e-30 106.2 0.0 2.9e-30 105.0 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Porphobil_deam PF01379.15 EDO18151.1 - 7.9e-88 292.9 0.0 1.1e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EDO18151.1 - 5e-23 81.0 0.5 8.8e-23 80.2 0.3 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Na_Ca_ex PF01699.19 EDO18153.1 - 1.2e-43 148.0 30.7 3e-23 81.9 3.6 3.6 2 2 1 3 3 3 2 Sodium/calcium exchanger protein FA_desaturase PF00487.19 EDO18153.1 - 0.029 13.8 0.1 0.029 13.8 0.1 2.8 3 0 0 3 3 3 0 Fatty acid desaturase Adaptin_N PF01602.15 EDO18154.1 - 7.3e-106 354.5 10.7 7.3e-106 354.5 7.4 1.9 2 0 0 2 2 2 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EDO18154.1 - 2.9e-59 198.4 0.0 8.6e-59 196.9 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EDO18154.1 - 4.1e-52 175.5 1.0 4.1e-52 175.5 0.7 2.6 2 0 0 2 2 2 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EDO18154.1 - 1.2e-06 28.6 9.4 0.011 15.9 0.0 5.0 3 1 3 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.2 EDO18154.1 - 0.083 13.2 2.3 0.24 11.7 0.1 2.9 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Peptidase_S49_N PF08496.5 EDO18154.1 - 0.16 11.7 8.2 0.21 11.3 2.6 2.6 2 0 0 2 2 2 0 Peptidase family S49 N-terminal HEAT PF02985.17 EDO18154.1 - 0.19 11.8 2.0 8.8 6.7 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 EDO18154.1 - 0.28 11.7 1.6 15 6.2 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat IZUMO PF15005.1 EDO18154.1 - 0.31 11.0 3.4 0.18 11.8 0.1 2.3 2 0 0 2 2 2 0 Izumo sperm-egg fusion Ribosomal_L7Ae PF01248.21 EDO18155.1 - 3.5e-26 90.5 0.2 5.5e-26 89.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3692 PF12469.3 EDO18155.1 - 0.17 12.1 0.4 0.29 11.3 0.3 1.6 1 1 0 1 1 1 0 CRISPR-associated protein RRM_1 PF00076.17 EDO18156.1 - 3.8e-06 26.4 0.1 9.6e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO18156.1 - 0.00057 19.8 0.4 0.002 18.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO18156.1 - 0.00086 19.1 0.2 0.0022 17.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMG14_17 PF01101.13 EDO18156.1 - 0.048 14.3 7.4 0.11 13.2 5.1 1.5 1 0 0 1 1 1 0 HMG14 and HMG17 TPR_11 PF13414.1 EDO18157.1 - 1e-28 98.7 14.5 5e-13 48.4 0.2 4.5 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EDO18157.1 - 2.8e-21 74.1 8.0 4.9e-06 25.9 0.1 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EDO18157.1 - 3e-20 70.4 6.2 3.3e-05 23.4 0.1 5.9 6 0 0 6 6 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 EDO18157.1 - 3.5e-17 61.0 6.7 0.001 19.0 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDO18157.1 - 8e-17 60.2 0.4 0.0013 19.2 0.0 5.7 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EDO18157.1 - 1.5e-13 50.9 1.4 2e-05 25.1 0.0 4.3 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDO18157.1 - 2.8e-12 46.7 10.0 0.0065 16.7 0.1 4.9 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EDO18157.1 - 7e-10 37.9 5.2 0.21 11.4 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDO18157.1 - 4.3e-09 36.1 5.4 8.4e-05 22.4 0.1 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 EDO18157.1 - 1.2e-08 34.9 2.9 0.076 13.1 0.0 4.9 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 EDO18157.1 - 1.9e-07 31.0 0.1 4.9 7.8 0.0 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO18157.1 - 6.1e-06 26.2 3.4 0.0034 17.4 0.5 3.4 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EDO18157.1 - 1.8e-05 24.1 0.5 0.6 10.0 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDO18157.1 - 3.1e-05 23.7 0.0 0.2 11.5 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat MIT PF04212.13 EDO18157.1 - 0.0038 17.0 0.3 2.4 8.0 0.0 3.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain BTAD PF03704.12 EDO18157.1 - 0.021 15.1 0.0 0.11 12.8 0.0 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.1 EDO18157.1 - 0.049 13.5 1.3 1.3 8.9 0.1 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF4248 PF14053.1 EDO18157.1 - 0.086 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Glyco_transf_34 PF05637.7 EDO18158.1 - 3.6e-75 252.5 0.0 6.1e-75 251.7 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EDO18158.1 - 0.0028 17.0 0.0 0.14 11.4 0.0 2.3 1 1 1 2 2 2 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.11 EDO18158.1 - 0.0067 16.2 0.1 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_tranf_2_4 PF13704.1 EDO18158.1 - 0.1 12.9 0.6 0.28 11.5 0.4 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 2 ARID PF01388.16 EDO18159.1 - 3e-21 75.0 0.3 3e-21 75.0 0.2 3.7 3 1 0 3 3 3 1 ARID/BRIGHT DNA binding domain Pkinase PF00069.20 EDO18160.1 - 1.5e-54 184.8 0.5 1.4e-52 178.3 0.3 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18160.1 - 3.7e-26 91.7 0.0 4.1e-23 81.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDO18160.1 - 1.1e-10 41.0 0.0 6.3e-10 38.4 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EDO18160.1 - 0.00035 20.4 0.0 0.00049 19.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EDO18160.1 - 0.055 12.5 0.1 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_18 PF13238.1 EDO18161.1 - 2.4e-08 34.3 0.2 4.9e-08 33.3 0.1 1.6 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EDO18161.1 - 2e-07 30.8 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 EDO18161.1 - 5e-06 27.3 0.0 6.6e-06 26.9 0.0 1.3 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EDO18161.1 - 5.5e-06 26.3 0.0 9.7e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EDO18161.1 - 3.2e-05 23.8 0.0 4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDO18161.1 - 0.0035 16.4 0.1 0.006 15.7 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin CPT PF07931.7 EDO18161.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF2075 PF09848.4 EDO18161.1 - 0.024 13.6 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EDO18161.1 - 0.025 14.8 0.1 0.041 14.0 0.1 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EDO18161.1 - 0.025 14.2 0.1 0.041 13.5 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EDO18161.1 - 0.033 13.0 0.1 0.052 12.3 0.1 1.4 1 1 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 EDO18161.1 - 0.038 14.2 0.1 0.044 14.0 0.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EDO18161.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EDO18161.1 - 0.061 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Alpha-amylase_C PF02806.13 EDO18161.1 - 0.085 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain AAA_30 PF13604.1 EDO18161.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EDO18161.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 EDO18161.1 - 0.1 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain Arch_ATPase PF01637.13 EDO18161.1 - 0.12 12.0 0.2 0.75 9.4 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 EDO18161.1 - 0.12 11.8 0.1 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EDO18161.1 - 0.16 11.1 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 PhoH-like protein SUV3_C PF12513.3 EDO18162.1 - 3.4e-16 58.4 1.5 9.6e-16 56.9 1.0 1.9 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EDO18162.1 - 1.3e-14 53.8 0.0 2.8e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO18162.1 - 0.00037 20.0 0.0 0.028 13.9 0.0 3.2 2 1 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C_4 PF13871.1 EDO18162.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Helicase_C-like F-box-like PF12937.2 EDO18163.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 F-box-like zf-C2H2_4 PF13894.1 EDO18165.1 - 6.9e-09 35.4 4.6 0.00074 19.6 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO18165.1 - 1.6e-06 28.0 8.4 0.0022 18.2 0.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type RRN7 PF11781.3 EDO18165.1 - 0.0037 16.7 0.1 2 7.9 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_jaz PF12171.3 EDO18165.1 - 0.009 16.1 2.3 0.63 10.2 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EDO18165.1 - 0.049 13.9 9.2 0.86 10.0 0.8 3.3 3 1 0 3 3 3 0 Zinc-finger double domain zf-CCHC_4 PF14392.1 EDO18165.1 - 0.11 12.1 1.1 8.1 6.2 0.1 2.5 2 0 0 2 2 2 0 Zinc knuckle C1_1 PF00130.17 EDO18165.1 - 0.32 10.7 2.1 14 5.4 0.1 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2_6 PF13912.1 EDO18165.1 - 7.9 6.5 6.7 13 5.8 0.2 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EDO18165.1 - 8.1 6.8 7.4 0.52 10.6 0.8 2.3 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DUF726 PF05277.7 EDO18166.1 - 0.033 13.0 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Rep_2 PF01719.12 EDO18166.1 - 0.05 13.1 4.5 0.087 12.3 3.1 1.5 1 0 0 1 1 1 0 Plasmid replication protein tRNA-synt_1 PF00133.17 EDO18167.1 - 4.2e-150 500.6 0.7 6e-150 500.1 0.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EDO18167.1 - 1.7e-26 92.8 0.3 6.8e-16 57.8 0.3 3.6 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EDO18167.1 - 7.1e-23 81.0 1.7 1.6e-22 79.9 1.2 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 EDO18167.1 - 0.00071 19.1 4.5 0.0018 17.8 3.1 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 EDO18167.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Pkinase PF00069.20 EDO18168.1 - 2.3e-58 197.4 0.6 2.7e-56 190.5 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18168.1 - 1.4e-26 93.1 0.3 4.6e-26 91.4 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO18168.1 - 0.0084 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Imm46 PF15585.1 EDO18168.1 - 0.096 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 46 APH PF01636.18 EDO18168.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CENP-N PF05238.8 EDO18169.1 - 2.4e-118 395.6 0.4 2.7e-118 395.4 0.3 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like Anp1 PF03452.9 EDO18170.1 - 6.8e-110 366.4 0.0 8.1e-110 366.2 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EDO18170.1 - 0.004 16.8 0.0 0.0078 15.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Alk_phosphatase PF00245.15 EDO18171.1 - 9.8e-125 416.5 0.0 1.2e-124 416.2 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EDO18171.1 - 0.005 16.2 0.0 0.0088 15.4 0.0 1.5 2 0 0 2 2 2 1 Metalloenzyme superfamily DUF4127 PF13552.1 EDO18171.1 - 0.069 11.5 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) RhoGAP PF00620.22 EDO18172.1 - 0.0048 16.5 6.3 0.0077 15.8 1.2 2.2 2 0 0 2 2 2 1 RhoGAP domain Vpu PF00558.14 EDO18172.1 - 0.014 14.9 0.3 0.014 14.9 0.2 2.8 2 1 1 3 3 3 0 Vpu protein HI0933_like PF03486.9 EDO18172.1 - 0.35 9.2 5.2 0.11 10.8 0.5 2.3 1 1 1 2 2 2 0 HI0933-like protein Imm35 PF15581.1 EDO18172.1 - 0.52 10.3 5.4 0.12 12.3 0.5 2.2 3 0 0 3 3 3 0 Immunity protein 35 Rabaptin PF03528.10 EDO18172.1 - 3.4 7.6 11.2 0.31 10.9 1.9 2.7 2 1 0 2 2 2 0 Rabaptin Sec3_C_2 PF15278.1 EDO18172.1 - 4.8 7.3 10.7 1 9.5 0.2 3.7 1 1 2 4 4 4 0 Sec3 exocyst complex subunit Grp1_Fun34_YaaH PF01184.14 EDO18173.1 - 2.3e-67 226.3 17.7 3e-67 225.9 12.3 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF4179 PF13786.1 EDO18173.1 - 0.012 15.8 4.1 0.022 14.9 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) DUF2631 PF10939.3 EDO18173.1 - 2.2 8.1 5.8 33 4.4 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2631) DUF3592 PF12158.3 EDO18173.1 - 3.3 7.4 6.8 83 2.9 4.7 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3592) HAD_2 PF13419.1 EDO18174.1 - 1.3e-16 61.3 0.0 7.1e-16 58.9 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO18174.1 - 9.4e-14 52.3 0.0 4.7e-10 40.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EDO18174.1 - 1.5e-10 40.6 0.0 2.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EDO18174.1 - 2.2e-07 31.2 0.0 3.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EDO18174.1 - 5.7e-05 22.5 0.0 0.0076 15.6 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase S6PP PF05116.8 EDO18174.1 - 0.081 12.2 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.7 EDO18174.1 - 0.083 12.4 0.5 12 5.4 0.0 3.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase NT5C PF06941.7 EDO18174.1 - 0.089 12.2 0.5 0.3 10.5 0.2 2.0 2 1 0 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) GTP_EFTU PF00009.22 EDO18175.1 - 2e-62 210.0 0.1 2.8e-62 209.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EDO18175.1 - 1.6e-37 127.7 0.0 4.9e-37 126.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EDO18175.1 - 4.7e-21 74.4 0.0 1.5e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EDO18175.1 - 1.4e-13 50.5 0.0 4.1e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EDO18175.1 - 1.8e-11 43.9 0.6 7.5e-11 41.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO18175.1 - 3.4e-05 23.7 0.1 7.7e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SUKH-4 PF14435.1 EDO18175.1 - 0.1 12.2 0.0 0.46 10.1 0.0 2.1 1 0 0 1 1 1 0 SUKH-4 immunity protein Sugar_tr PF00083.19 EDO18176.1 - 4.1e-99 332.1 24.9 3e-54 184.3 6.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EDO18176.1 - 7.9e-26 90.5 38.2 1.9e-21 76.1 10.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily COX7C PF02935.11 EDO18176.1 - 0.043 13.6 0.0 0.16 11.7 0.0 2.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc MFS_3 PF05977.8 EDO18176.1 - 1.4 6.9 9.6 0.91 7.5 1.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Phage_holin_2 PF04550.7 EDO18176.1 - 9.8 6.3 10.2 0.69 10.0 1.8 2.9 3 0 0 3 3 3 0 Phage holin family 2 RhoGAP PF00620.22 EDO18177.1 - 1.1e-30 106.2 0.4 2.5e-19 69.3 0.0 2.6 2 0 0 2 2 2 2 RhoGAP domain ThiF PF00899.16 EDO18178.1 - 1.9e-34 118.3 0.0 4e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EDO18178.1 - 5.9e-25 86.6 2.0 9.9e-25 85.9 0.4 2.2 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EDO18178.1 - 1.5e-20 72.3 3.8 2.6e-20 71.5 2.6 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EDO18178.1 - 5.7e-05 23.1 2.6 0.00024 21.1 1.8 2.2 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EDO18178.1 - 0.0095 16.1 0.0 0.06 13.6 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EDO18178.1 - 0.028 14.5 0.0 0.1 12.6 0.0 2.0 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Iso_dh PF00180.15 EDO18179.1 - 1.5e-102 343.1 0.0 1.7e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase UBA PF00627.26 EDO18180.1 - 3.5e-09 36.2 0.1 7.7e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EDO18180.1 - 0.00051 19.5 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Actin PF00022.14 EDO18181.1 - 3.2e-29 101.5 0.0 2.6e-20 72.2 0.0 3.6 3 1 0 3 3 3 3 Actin MreB_Mbl PF06723.8 EDO18181.1 - 1.3e-05 23.9 0.0 0.00066 18.3 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein TPK_catalytic PF04263.11 EDO18182.1 - 4.3e-20 71.5 0.1 2.9e-17 62.3 0.0 2.2 1 1 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EDO18182.1 - 2.2e-12 46.4 0.3 6.1e-12 45.0 0.1 1.8 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TFIID-18kDa PF02269.11 EDO18183.1 - 1.4e-36 124.1 0.5 8.9e-36 121.5 0.1 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit KH_1 PF00013.24 EDO18184.1 - 0.0003 20.3 0.4 0.00061 19.3 0.3 1.5 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 EDO18185.1 - 4.1e-75 253.1 27.0 8.6e-40 136.6 5.3 4.1 2 1 2 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins G-patch_2 PF12656.2 EDO18186.1 - 2.5e-21 75.2 1.5 8e-21 73.6 0.1 2.3 2 0 0 2 2 2 1 DExH-box splicing factor binding site She9_MDM33 PF05546.6 EDO18187.1 - 7.7e-88 293.4 16.8 7.7e-88 293.4 11.6 1.8 2 0 0 2 2 2 1 She9 / Mdm33 family ATG16 PF08614.6 EDO18187.1 - 0.0044 16.8 8.3 0.0044 16.8 5.8 2.7 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) PAS_9 PF13426.1 EDO18187.1 - 0.016 15.5 0.6 0.15 12.4 0.0 2.6 1 1 1 2 2 2 0 PAS domain FUSC PF04632.7 EDO18187.1 - 0.11 10.8 0.4 0.19 10.1 0.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA PF00004.24 EDO18188.1 - 2.4e-46 157.2 0.0 6.8e-46 155.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO18188.1 - 1.4e-08 34.5 0.1 5.5e-08 32.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDO18188.1 - 3e-08 33.7 0.0 6.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDO18188.1 - 3.6e-07 30.3 0.1 1.7e-06 28.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EDO18188.1 - 7.7e-07 29.3 1.8 0.00014 21.9 0.3 3.2 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 EDO18188.1 - 5.9e-05 22.1 0.0 0.0001 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EDO18188.1 - 6.6e-05 22.8 0.0 0.00033 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO18188.1 - 0.00013 22.7 0.0 0.00053 20.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EDO18188.1 - 0.00036 19.6 0.0 0.00084 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 EDO18188.1 - 0.00047 19.9 0.1 0.0015 18.2 0.0 1.9 3 0 0 3 3 1 1 NTPase Zeta_toxin PF06414.7 EDO18188.1 - 0.00085 18.4 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EDO18188.1 - 0.0015 18.2 0.1 0.0037 16.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 EDO18188.1 - 0.0018 17.8 0.0 0.005 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EDO18188.1 - 0.0021 18.2 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 EDO18188.1 - 0.0024 17.4 0.0 0.0084 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EDO18188.1 - 0.0025 16.5 0.0 0.0045 15.7 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA_28 PF13521.1 EDO18188.1 - 0.0035 17.3 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EDO18188.1 - 0.0038 16.9 0.1 0.05 13.2 0.0 2.4 1 1 1 2 2 2 1 NACHT domain AAA_33 PF13671.1 EDO18188.1 - 0.0038 17.1 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EDO18188.1 - 0.004 16.5 0.7 0.12 11.7 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EDO18188.1 - 0.0042 16.6 0.0 0.0097 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EDO18188.1 - 0.005 16.3 0.0 0.16 11.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EDO18188.1 - 0.0057 15.8 0.1 0.015 14.4 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 EDO18188.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EDO18188.1 - 0.0062 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO18188.1 - 0.013 15.8 0.0 0.045 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EDO18188.1 - 0.013 15.1 0.8 0.11 12.2 0.0 2.4 2 1 1 3 3 2 0 Archaeal ATPase IstB_IS21 PF01695.12 EDO18188.1 - 0.015 14.7 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 EDO18188.1 - 0.019 15.3 1.6 2.3 8.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 EDO18188.1 - 0.056 13.0 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.22 EDO18188.1 - 0.085 13.1 0.3 0.35 11.1 0.0 2.3 2 1 0 2 2 2 0 ABC transporter SKI PF01202.17 EDO18188.1 - 0.09 12.6 0.0 15 5.4 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase NB-ARC PF00931.17 EDO18188.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF1640 PF07798.6 EDO18189.1 - 2.3e-09 37.5 4.9 3.5e-09 36.9 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) ECH PF00378.15 EDO18190.1 - 2.7e-16 59.4 0.0 3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family WH1 PF00568.18 EDO18191.1 - 4.6e-33 113.2 0.0 6.3e-33 112.8 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EDO18191.1 - 0.0001 21.7 0.8 0.00022 20.6 0.5 1.6 1 0 0 1 1 1 1 WH2 motif GCIP PF13324.1 EDO18192.1 - 6.1e-05 22.3 5.1 0.00025 20.3 3.3 2.1 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting STN1_2 PF09170.5 EDO18192.1 - 0.21 11.3 5.1 0.49 10.1 3.5 1.6 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF4473 PF14747.1 EDO18192.1 - 0.29 11.3 3.2 10 6.4 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) Ribosomal_S30 PF04758.9 EDO18193.1 - 9.1e-30 102.2 5.1 9.7e-30 102.1 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Aminotran_5 PF00266.14 EDO18194.1 - 2.3e-37 128.6 0.0 3.1e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Glyco_hydro_77 PF02446.12 EDO18194.1 - 0.08 11.5 0.0 1.6 7.2 0.0 2.0 2 0 0 2 2 2 0 4-alpha-glucanotransferase Hus1 PF04005.7 EDO18195.1 - 6.2e-19 68.0 6.6 7e-17 61.2 4.6 2.2 1 1 0 1 1 1 1 Hus1-like protein NAD_binding_10 PF13460.1 EDO18196.1 - 7.9e-09 35.7 0.0 1.1e-07 32.1 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EDO18196.1 - 4.7e-06 26.2 0.0 0.00056 19.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EDO18196.1 - 7.9e-05 22.6 0.0 0.00017 21.5 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EDO18196.1 - 0.0012 17.8 0.0 0.13 11.0 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain 3Beta_HSD PF01073.14 EDO18196.1 - 0.0013 17.5 0.0 0.0058 15.3 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EDO18196.1 - 0.072 12.0 0.0 4.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein TPR_1 PF00515.23 EDO18197.1 - 3.1e-07 29.7 0.4 0.0008 18.9 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDO18197.1 - 3e-06 26.7 1.0 0.017 14.7 0.0 2.9 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EDO18197.1 - 3.4e-05 23.4 0.2 0.024 14.5 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF4559 PF15112.1 EDO18197.1 - 0.077 12.1 2.7 0.093 11.8 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) TPR_8 PF13181.1 EDO18197.1 - 0.094 12.5 0.3 5.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EDO18197.1 - 0.12 12.6 1.6 0.52 10.6 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat V_ATPase_I PF01496.14 EDO18198.1 - 0.36 8.6 9.6 0.5 8.1 6.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HAUS6_N PF14661.1 EDO18198.1 - 0.84 8.9 7.5 1.4 8.1 4.8 1.6 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus zf-C2H2_4 PF13894.1 EDO18199.1 - 2.1e-06 27.6 15.0 0.048 14.0 0.6 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO18199.1 - 1.1e-05 25.4 13.9 0.0044 17.2 0.4 4.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO18199.1 - 0.047 13.9 16.7 0.9 9.9 0.3 4.6 4 0 0 4 4 4 0 Zinc-finger double domain PAT1 PF09770.4 EDO18199.1 - 0.36 9.0 27.7 0.45 8.6 19.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 EDO18199.1 - 0.66 9.7 8.3 1.1 9.0 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) IlvC PF01450.14 EDO18200.1 - 7.2e-47 158.9 0.0 2.2e-46 157.3 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 EDO18200.1 - 2.5e-45 153.8 0.0 3.6e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EDO18200.1 - 0.094 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase OS-D PF03392.8 EDO18203.1 - 0.0039 17.1 0.6 0.012 15.5 0.3 2.0 1 1 0 1 1 1 1 Insect pheromone-binding family, A10/OS-D eIF2A PF08662.6 EDO18204.1 - 1.7e-78 262.8 0.1 6.5e-78 260.9 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EDO18204.1 - 0.00023 20.9 2.7 7.6 6.5 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat EMP70 PF02990.11 EDO18205.1 - 1.7e-200 666.9 9.3 2.4e-200 666.4 6.5 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Actin PF00022.14 EDO18206.1 - 5.2e-58 196.3 0.0 6.3e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Actin Gaa1 PF04114.9 EDO18207.1 - 5.7e-117 391.5 16.0 8.6e-112 374.4 3.0 2.1 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component Aldo_ket_red PF00248.16 EDO18208.1 - 0.011 14.6 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Aldo/keto reductase family rve PF00665.21 EDO18208.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Aminotran_1_2 PF00155.16 EDO18209.1 - 1.6e-35 122.7 0.0 2.1e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DnaJ PF00226.26 EDO18210.1 - 3.9e-24 84.1 3.4 7.6e-24 83.2 2.4 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDO18210.1 - 1.8e-20 72.6 0.3 4.2e-15 55.4 0.0 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDO18210.1 - 2.8e-10 40.0 13.5 3.4e-08 33.4 5.5 2.6 1 1 1 2 2 2 2 DnaJ central domain zf-CHY PF05495.7 EDO18210.1 - 1.7 8.8 9.0 28 4.9 5.2 2.4 1 1 1 2 2 2 0 CHY zinc finger Securin PF04856.8 EDO18211.1 - 3.3e-26 92.4 17.3 4.5e-26 92.0 12.0 1.2 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor Ribosomal_L34 PF00468.12 EDO18212.1 - 4.3e-19 67.9 5.9 6.9e-19 67.2 4.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Sulfate_transp PF00916.15 EDO18213.1 - 3.2e-84 282.2 4.1 3.2e-84 282.2 2.8 2.2 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EDO18213.1 - 2.5e-30 103.9 3.2 2.5e-30 103.9 2.2 2.3 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EDO18213.1 - 6.6e-05 22.3 0.0 0.00015 21.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EDO18213.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_1 PF07690.11 EDO18214.1 - 1.9e-48 165.0 39.9 1.9e-48 165.0 27.6 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO18214.1 - 6.7e-18 64.5 8.1 6.7e-18 64.5 5.6 3.5 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EDO18214.1 - 7.8e-07 27.6 14.6 7.8e-07 27.6 10.1 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TRM PF02005.11 EDO18215.1 - 9.3e-142 472.3 0.0 1.2e-141 472.0 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EDO18215.1 - 3.3e-05 23.5 0.1 7.2e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 EDO18215.1 - 0.032 13.5 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.1 EDO18215.1 - 0.071 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FliH PF02108.11 EDO18215.1 - 0.085 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Flagellar assembly protein FliH Cons_hypoth95 PF03602.10 EDO18215.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PrmA PF06325.8 EDO18215.1 - 0.16 11.0 0.2 0.27 10.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CBFD_NFYB_HMF PF00808.18 EDO18216.1 - 0.00089 19.2 0.1 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1762 PF08574.5 EDO18216.1 - 0.51 10.7 10.4 0.14 12.5 1.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1762) Pex16 PF08610.5 EDO18216.1 - 6.1 5.7 6.6 11 4.8 2.1 2.0 1 1 1 2 2 2 0 Peroxisomal membrane protein (Pex16) Nyv1_N PF09426.5 EDO18217.1 - 1.4e-67 225.6 0.9 2.4e-67 224.8 0.6 1.4 1 0 0 1 1 1 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.16 EDO18217.1 - 1.9e-28 97.9 2.3 2.9e-28 97.3 1.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Retrotrans_gag PF03732.12 EDO18217.1 - 0.048 13.7 0.4 0.11 12.6 0.1 1.7 1 1 0 1 1 1 0 Retrotransposon gag protein Fzo_mitofusin PF04799.8 EDO18217.1 - 0.1 11.9 1.2 0.17 11.2 0.8 1.3 1 0 0 1 1 1 0 fzo-like conserved region F-box-like PF12937.2 EDO18218.1 - 7.6e-05 22.3 0.1 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like MIT PF04212.13 EDO18218.1 - 0.0011 18.7 1.4 0.01 15.7 1.2 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain F-box PF00646.28 EDO18218.1 - 0.0013 18.3 0.3 0.003 17.1 0.2 1.5 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.23 EDO18218.1 - 0.012 15.1 0.1 0.029 13.9 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO18218.1 - 0.067 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO18218.1 - 0.1 12.4 0.1 0.42 10.5 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EDO18219.1 - 6.6e-22 78.5 0.0 9.7e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO18219.1 - 2e-16 60.2 0.0 6.1e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO18219.1 - 1.2e-11 44.5 0.0 2.8e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EDO18219.1 - 4.8e-06 25.8 0.1 0.00052 19.1 0.1 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EDO18219.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF2305 PF10230.4 EDO18219.1 - 0.0013 18.1 0.0 0.006 16.0 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 EDO18219.1 - 0.0033 17.0 0.0 0.039 13.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.9 EDO18219.1 - 0.0036 16.6 0.0 0.0079 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ndr PF03096.9 EDO18219.1 - 0.0051 15.3 0.0 0.012 14.1 0.0 1.5 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.6 EDO18219.1 - 0.0073 16.0 0.0 0.079 12.6 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.8 EDO18219.1 - 0.0078 15.8 0.0 0.017 14.7 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.8 EDO18219.1 - 0.0078 15.8 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Thioesterase PF00975.15 EDO18219.1 - 0.012 15.8 0.0 0.7 10.0 0.0 2.7 3 0 0 3 3 3 0 Thioesterase domain CDC45 PF02724.9 EDO18220.1 - 0.016 13.3 8.8 0.018 13.1 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein NUT_C PF12882.2 EDO18220.1 - 0.37 10.3 5.7 0.53 9.8 4.0 1.2 1 0 0 1 1 1 0 NUT protein C terminal RRN3 PF05327.6 EDO18220.1 - 0.94 7.5 10.1 1.1 7.2 7.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Na_trans_assoc PF06512.8 EDO18220.1 - 1.6 8.6 19.1 2.2 8.2 13.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Mitofilin PF09731.4 EDO18220.1 - 2.9 6.4 14.9 3.6 6.1 10.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein BUD22 PF09073.5 EDO18220.1 - 3.3 6.6 15.6 3.9 6.4 10.8 1.1 1 0 0 1 1 1 0 BUD22 Trypan_PARP PF05887.6 EDO18220.1 - 3.5 7.4 8.6 4.3 7.1 6.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HSP70 PF00012.15 EDO18220.1 - 6.9 4.4 9.0 8.3 4.1 6.2 1.0 1 0 0 1 1 1 0 Hsp70 protein CH PF00307.26 EDO18221.1 - 9.4e-73 241.1 0.3 1.1e-20 73.7 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EDO18221.1 - 2.7e-08 33.3 0.0 1.2 8.8 0.0 4.4 4 0 0 4 4 4 3 CAMSAP CH domain EF-hand_7 PF13499.1 EDO18221.1 - 7.8e-05 22.7 0.6 0.0017 18.4 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EDO18221.1 - 0.017 14.3 0.1 2.2 7.8 0.0 3.4 3 0 0 3 3 3 0 EF hand tRNA_int_endo PF01974.12 EDO18222.1 - 1.3e-26 92.1 0.2 3.8e-26 90.7 0.2 1.7 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EDO18222.1 - 0.076 12.5 0.1 2.8 7.5 0.0 2.5 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain F-box-like PF12937.2 EDO18223.1 - 0.00037 20.1 0.1 0.00085 18.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO18223.1 - 0.0011 18.6 0.0 0.0029 17.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUF3760 PF12586.3 EDO18223.1 - 0.024 14.4 0.1 0.068 13.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Lsm_C PF14894.1 EDO18223.1 - 0.042 13.3 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 Lsm C-terminal Flocculin_t3 PF13928.1 EDO18224.1 - 1.9e-12 47.0 23.3 1.9e-12 47.0 16.1 2.6 3 0 0 3 3 3 1 Flocculin type 3 repeat Pkinase PF00069.20 EDO18225.1 - 1.8e-69 233.8 0.0 2.3e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18225.1 - 3.1e-30 105.1 0.0 5.1e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDO18225.1 - 4.1e-05 22.7 0.1 0.00017 20.7 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO18225.1 - 0.00034 20.4 0.9 0.0017 18.1 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EDO18225.1 - 0.0028 16.6 0.0 0.066 12.1 0.0 2.2 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EDO18225.1 - 0.073 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Chorion_3 PF05387.6 EDO18225.1 - 0.58 9.5 3.2 0.92 8.8 2.2 1.2 1 0 0 1 1 1 0 Chorion family 3 Rgp1 PF08737.5 EDO18226.1 - 1.2e-115 386.8 9.9 1.2e-115 386.8 6.9 1.9 2 0 0 2 2 2 1 Rgp1 Arrestin_C PF02752.17 EDO18226.1 - 0.00053 20.0 0.4 0.082 13.0 0.1 3.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Dopey_N PF04118.9 EDO18228.1 - 3.1e-117 390.7 0.4 3.1e-117 390.7 0.3 3.3 3 0 0 3 3 3 1 Dopey, N-terminal Abhydrolase_2 PF02230.11 EDO18229.1 - 3.5e-60 203.1 0.0 4.3e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EDO18229.1 - 6.2e-08 32.5 0.0 9.9e-08 31.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EDO18229.1 - 1.8e-07 30.7 0.0 4.8e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EDO18229.1 - 4.7e-05 23.3 0.0 0.00095 19.1 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EDO18229.1 - 0.011 14.9 0.0 1.2 8.2 0.0 2.7 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EDO18229.1 - 0.024 14.1 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EDO18229.1 - 0.041 13.1 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Dienelactone hydrolase family Mod_r PF07200.8 EDO18230.1 - 3.1e-24 85.6 13.1 3.8e-24 85.3 9.1 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Retrotrans_gag PF03732.12 EDO18230.1 - 0.00017 21.5 6.3 0.05 13.6 0.4 3.3 1 1 2 3 3 3 2 Retrotransposon gag protein DUF4298 PF14131.1 EDO18230.1 - 0.0011 18.8 2.5 0.0011 18.8 1.8 2.5 2 1 1 3 3 2 1 Domain of unknown function (DUF4298) Enkurin PF13864.1 EDO18230.1 - 0.0016 18.5 7.1 0.18 11.9 0.6 2.5 1 1 1 2 2 2 2 Calmodulin-binding Nup54 PF13874.1 EDO18230.1 - 0.013 15.1 2.8 0.023 14.3 2.0 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 GAS PF13851.1 EDO18230.1 - 0.023 13.9 13.6 0.014 14.6 7.7 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DASH_Dad3 PF08656.5 EDO18230.1 - 0.03 13.9 4.2 0.046 13.4 0.7 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 SpoOE-like PF09388.5 EDO18230.1 - 0.032 13.7 0.8 7.6 6.1 0.0 2.9 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein KNOX2 PF03791.8 EDO18230.1 - 0.033 13.4 3.1 0.067 12.4 0.0 2.8 3 1 0 3 3 3 0 KNOX2 domain DUF607 PF04678.8 EDO18230.1 - 0.038 13.9 2.5 0.052 13.4 0.2 1.9 1 1 0 2 2 2 0 Protein of unknown function, DUF607 DUF1975 PF09318.5 EDO18230.1 - 0.042 13.4 4.4 0.067 12.7 3.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1975) DUF1053 PF06327.9 EDO18230.1 - 0.11 12.8 4.9 0.49 10.7 3.0 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1053) BLOC1_2 PF10046.4 EDO18230.1 - 0.16 12.1 7.6 0.17 12.0 1.7 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LOH1CR12 PF10158.4 EDO18230.1 - 0.31 10.8 3.8 0.76 9.5 0.2 2.4 2 1 1 3 3 3 0 Tumour suppressor protein Viral_P18 PF04521.8 EDO18230.1 - 0.38 10.1 3.6 0.14 11.6 0.6 1.8 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Lipoprotein_20 PF13942.1 EDO18230.1 - 0.48 9.9 6.0 0.21 11.1 2.0 1.8 1 1 1 2 2 2 0 YfhG lipoprotein IncA PF04156.9 EDO18230.1 - 0.52 9.8 13.7 0.57 9.7 7.2 2.0 1 1 1 2 2 2 0 IncA protein Fib_alpha PF08702.5 EDO18230.1 - 0.56 10.3 6.0 0.78 9.8 4.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 EDO18230.1 - 0.62 9.9 8.6 0.44 10.3 2.5 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 EDO18230.1 - 0.65 8.3 8.3 0.91 7.8 5.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Fzo_mitofusin PF04799.8 EDO18230.1 - 0.67 9.3 7.9 1 8.7 1.4 2.2 1 1 1 2 2 2 0 fzo-like conserved region Cep57_MT_bd PF06657.8 EDO18230.1 - 0.7 9.8 9.3 1.9 8.4 0.6 3.1 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.3 EDO18230.1 - 1.1 9.0 7.8 0.35 10.6 1.0 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding PilO PF04350.8 EDO18230.1 - 1.2 9.0 6.4 0.52 10.1 0.7 2.2 2 0 0 2 2 2 0 Pilus assembly protein, PilO DivIC PF04977.10 EDO18230.1 - 1.5 8.3 9.5 0.35 10.3 0.5 2.9 2 1 1 3 3 3 0 Septum formation initiator Uds1 PF15456.1 EDO18230.1 - 1.7 8.6 7.1 5.4 7.0 0.3 2.3 1 1 0 2 2 2 0 Up-regulated During Septation Seryl_tRNA_N PF02403.17 EDO18230.1 - 2 8.4 9.6 2.1 8.3 1.4 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.7 EDO18230.1 - 2.4 7.9 5.9 0.6 9.8 1.1 2.0 1 1 2 3 3 3 0 Laminin Domain II APG6 PF04111.7 EDO18230.1 - 2.6 7.0 13.9 12 4.8 9.6 1.8 1 1 0 1 1 1 0 Autophagy protein Apg6 Lge1 PF11488.3 EDO18230.1 - 2.7 8.2 6.6 1 9.6 1.3 2.5 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Syntaxin-6_N PF09177.6 EDO18230.1 - 3.1 8.2 6.5 26 5.2 0.6 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3373 PF11853.3 EDO18230.1 - 5.8 5.3 9.2 51 2.2 6.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) YgaB PF14182.1 EDO18230.1 - 8.4 6.7 10.3 0.82 9.9 3.0 2.4 2 2 0 2 2 2 0 YgaB-like protein Asp PF00026.18 EDO18231.1 - 4.2e-75 252.9 7.5 4.2e-75 252.9 5.2 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO18231.1 - 2.4e-08 34.0 2.8 2.4e-08 34.0 2.0 2.7 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EDO18231.1 - 0.02 14.4 0.2 0.17 11.4 0.1 2.4 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EDO18231.1 - 0.027 14.9 1.6 16 6.0 0.1 3.9 3 0 0 3 3 3 0 Aspartyl protease RVP PF00077.15 EDO18231.1 - 0.043 13.7 0.5 10 6.0 0.0 3.1 3 0 0 3 3 3 0 Retroviral aspartyl protease GATase PF00117.23 EDO18232.1 - 8.1e-11 41.7 0.0 1.3e-10 41.0 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I TFIID_20kDa PF03847.8 EDO18233.1 - 3.4e-32 110.5 0.4 3.4e-32 110.5 0.2 2.3 3 0 0 3 3 3 1 Transcription initiation factor TFIID subunit A Zip PF02535.17 EDO18234.1 - 8.2e-65 218.8 3.8 1.1e-64 218.4 2.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.8 EDO18234.1 - 0.054 12.6 5.7 0.03 13.5 1.6 1.9 2 0 0 2 2 2 0 UNC-50 family dCMP_cyt_deam_1 PF00383.17 EDO18235.1 - 1.1e-22 79.5 0.0 1.6e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EDO18235.1 - 2.3e-05 24.0 0.0 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.1 EDO18235.1 - 0.003 17.4 0.4 0.39 10.5 0.3 2.3 1 1 0 1 1 1 1 Bd3614-like deaminase MafB19-deam PF14437.1 EDO18235.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 MafB19-like deaminase OTT_1508_deam PF14441.1 EDO18235.1 - 0.053 13.3 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 OTT_1508-like deaminase FAD_binding_2 PF00890.19 EDO18236.1 - 2.6e-125 418.5 2.3 3.3e-125 418.1 1.6 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EDO18236.1 - 2.9e-48 162.9 1.4 4.4e-48 162.3 1.0 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EDO18236.1 - 7.7e-09 35.7 0.0 0.00037 20.4 0.5 3.1 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EDO18236.1 - 1e-06 27.9 3.0 0.0068 15.3 1.9 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EDO18236.1 - 7.1e-06 25.2 0.1 0.0014 17.7 0.1 2.9 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 EDO18236.1 - 1.4e-05 24.2 1.3 0.0002 20.3 0.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EDO18236.1 - 0.0048 16.0 0.1 0.0091 15.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EDO18236.1 - 0.033 12.6 0.4 0.25 9.7 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_1 PF00175.16 EDO18237.1 - 4.2e-27 94.8 0.0 6.2e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EDO18237.1 - 2.3e-24 85.3 0.0 4e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EDO18237.1 - 5.1e-09 36.2 0.0 4e-07 30.0 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Carb_kinase PF01256.12 EDO18238.1 - 1.4e-62 211.1 0.0 3.1e-62 210.0 0.0 1.5 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EDO18238.1 - 4e-05 22.9 0.0 5.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase His_Phos_1 PF00300.17 EDO18239.1 - 6.6e-45 153.0 0.0 8.7e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RabGAP-TBC PF00566.13 EDO18240.1 - 7.7e-19 68.0 11.3 7.7e-19 68.0 7.8 2.1 1 1 1 2 2 2 1 Rab-GTPase-TBC domain DUF2423 PF10338.4 EDO18240.1 - 0.22 11.5 3.1 0.44 10.5 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2423) LRR_6 PF13516.1 EDO18241.1 - 0.44 10.7 4.8 49 4.4 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat Nsp1_C PF05064.8 EDO18242.1 - 1.1e-37 128.2 6.1 1.1e-37 128.2 4.2 1.9 1 1 1 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EDO18242.1 - 0.0071 16.5 27.3 0.0071 16.5 18.9 7.0 1 1 5 6 6 6 3 Nucleoporin FG repeat region Baculo_p24 PF05073.7 EDO18242.1 - 0.009 15.5 3.8 0.018 14.6 2.6 1.5 1 0 0 1 1 1 1 Baculovirus P24 capsid protein DNA_primase_lrg PF04104.9 EDO18242.1 - 0.038 13.2 0.7 0.063 12.5 0.5 1.3 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Caudo_TAP PF02413.12 EDO18242.1 - 0.13 12.3 5.4 0.4 10.8 3.4 2.1 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF4200 PF13863.1 EDO18242.1 - 0.48 10.3 8.2 0.36 10.7 3.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Laminin_II PF06009.7 EDO18242.1 - 0.76 9.5 15.0 0.47 10.1 6.0 2.7 1 1 2 3 3 3 0 Laminin Domain II Muted PF14942.1 EDO18242.1 - 0.77 9.6 4.3 1.1 9.1 2.2 1.7 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF87 PF01935.12 EDO18242.1 - 2.1 8.1 9.9 13 5.4 6.8 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF87 DUF342 PF03961.8 EDO18242.1 - 6.4 5.0 11.6 3.4 5.9 5.5 1.9 1 1 2 3 3 3 0 Protein of unknown function (DUF342) DUF3414 PF11894.3 EDO18243.1 - 0 1579.2 75.1 0 1579.0 52.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) SAM_decarbox PF01536.11 EDO18244.1 - 1.5e-99 332.8 5.2 1.7e-99 332.6 3.6 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase DUF498 PF04430.9 EDO18244.1 - 0.055 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Ecm33 PF12454.3 EDO18245.1 - 0.0059 16.4 0.2 0.0059 16.4 0.1 1.5 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein EamA PF00892.15 EDO18246.1 - 3.2e-29 101.5 25.9 3.9e-17 62.4 3.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EDO18246.1 - 3.1e-06 27.3 9.5 3.1e-06 27.3 6.6 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter ApbA PF02558.11 EDO18248.1 - 9e-30 103.1 0.0 1.3e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EDO18248.1 - 1.7e-22 79.7 0.0 2.7e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 EDO18248.1 - 2.3e-05 24.1 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EDO18248.1 - 0.0022 18.3 0.0 0.0042 17.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent BBS2_C PF14782.1 EDO18248.1 - 0.0048 15.5 0.2 0.0071 14.9 0.2 1.1 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal AA_permease PF00324.16 EDO18249.1 - 3.6e-150 500.4 35.4 4.1e-150 500.2 24.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO18249.1 - 5.7e-40 137.1 37.3 6.7e-40 136.9 25.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF373 PF04123.8 EDO18249.1 - 2 7.3 7.6 5.3 5.9 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF373) AA_permease PF00324.16 EDO18250.1 - 1.5e-147 491.8 45.2 1.8e-147 491.5 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO18250.1 - 9.3e-40 136.4 46.6 1.2e-39 136.1 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease Imm11 PF15563.1 EDO18251.1 - 0.0047 16.0 0.1 0.0049 16.0 0.1 1.1 1 0 0 1 1 1 1 Immunity protein 11 Baculo_RING PF05883.6 EDO18251.1 - 0.01 15.6 0.4 0.014 15.2 0.3 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain 6PF2K PF01591.13 EDO18252.1 - 1.9e-48 164.4 4.9 3.1e-48 163.7 3.4 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase KTI12 PF08433.5 EDO18252.1 - 1.4e-05 24.4 0.2 0.00018 20.8 0.0 2.6 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EDO18252.1 - 8.7e-05 22.4 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO18252.1 - 0.00084 19.6 0.7 0.0045 17.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EDO18252.1 - 0.0046 17.7 0.0 0.012 16.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain WRW PF10206.4 EDO18252.1 - 0.019 14.9 0.1 0.14 12.2 0.0 2.3 1 1 1 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f AAA_22 PF13401.1 EDO18252.1 - 0.057 13.5 0.0 0.32 11.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain PDT PF00800.13 EDO18253.1 - 2.9e-51 173.6 0.5 3.9e-51 173.1 0.3 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT_4 PF13291.1 EDO18253.1 - 0.057 13.7 0.7 1.3 9.3 0.0 2.7 2 1 0 2 2 2 0 ACT domain ACT PF01842.20 EDO18253.1 - 0.088 12.3 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 ACT domain MCE PF02470.15 EDO18253.1 - 0.36 10.8 2.4 11 6.1 0.0 2.3 2 0 0 2 2 2 0 mce related protein DcpS PF05652.7 EDO18254.1 - 0.99 9.8 6.9 0.99 9.8 0.0 3.1 2 2 2 4 4 4 0 Scavenger mRNA decapping enzyme (DcpS) N-terminal ORF6C PF10552.4 EDO18254.1 - 2.1 8.1 7.6 0.21 11.2 0.2 3.0 4 0 0 4 4 4 0 ORF6C domain DUF1752 PF08550.5 EDO18255.1 - 1.5e-10 40.4 0.8 4.7e-10 38.8 0.5 2.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Brix PF04427.13 EDO18256.1 - 6.7e-47 159.6 0.2 8.7e-47 159.2 0.1 1.1 1 0 0 1 1 1 1 Brix domain 2-oxoacid_dh PF00198.18 EDO18258.1 - 1.4e-76 256.8 0.3 2.1e-76 256.2 0.2 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EDO18258.1 - 7e-18 64.0 0.1 1.7e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EDO18258.1 - 1.3e-14 53.5 0.1 3.4e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 e3 binding domain CENP-T PF15511.1 EDO18258.1 - 0.013 14.7 0.8 0.019 14.2 0.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF3614 PF12267.3 EDO18258.1 - 0.15 12.2 3.0 0.29 11.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3614) Ribosomal_60s PF00428.14 EDO18258.1 - 9.3 6.7 12.7 1.6 9.1 1.5 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein Mito_carr PF00153.22 EDO18259.1 - 2e-61 203.7 4.1 1.3e-24 85.6 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L13 PF00572.13 EDO18260.1 - 4e-26 91.5 0.1 7.4e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Fork_head PF00250.13 EDO18261.1 - 8.3e-37 125.1 1.1 8.3e-37 125.1 0.7 3.4 3 0 0 3 3 3 2 Fork head domain FHA PF00498.21 EDO18261.1 - 2.3e-10 40.4 0.1 1.1e-09 38.2 0.1 2.3 1 0 0 1 1 1 1 FHA domain Fungal_trans PF04082.13 EDO18262.1 - 2.9e-24 85.3 14.4 3.7e-24 84.9 0.6 3.3 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO18262.1 - 2.7e-11 43.1 12.3 4.7e-11 42.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_Packaging_2 PF11123.3 EDO18262.1 - 0.053 13.4 0.1 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 DNA packaging protein MMS19_N PF14500.1 EDO18263.1 - 6.7e-92 307.4 9.4 5e-89 298.0 0.7 4.7 4 1 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EDO18263.1 - 4.3e-90 302.4 21.6 4.3e-90 302.4 15.0 4.0 5 1 0 5 5 5 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 EDO18263.1 - 1.9e-06 28.0 0.4 0.14 12.4 0.0 4.3 4 1 0 5 5 5 2 HEAT repeats HEAT PF02985.17 EDO18263.1 - 8.5e-06 25.4 3.8 0.82 9.9 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EDO18263.1 - 0.0007 20.0 7.1 2.9 8.4 0.0 6.2 6 1 1 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDO18263.1 - 0.0063 16.8 0.7 0.099 13.0 0.0 3.5 3 1 0 3 3 3 1 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 EDO18263.1 - 0.039 13.9 1.7 18 5.3 0.0 4.4 4 2 1 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Toxin_28 PF08115.6 EDO18263.1 - 0.059 13.0 0.2 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 SFI toxin family WavE PF07507.6 EDO18264.1 - 0.057 12.2 6.9 0.078 11.8 4.8 1.2 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis SNF2_N PF00176.18 EDO18266.1 - 7.9e-86 287.5 0.5 7.9e-86 287.5 0.4 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EDO18266.1 - 1.3e-20 73.0 0.1 5.4e-20 71.1 0.1 2.2 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EDO18266.1 - 5.3e-19 67.8 0.1 2e-16 59.6 0.0 3.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EDO18266.1 - 3.3e-13 49.6 0.5 3.3e-13 49.6 0.3 4.9 4 1 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EDO18266.1 - 0.076 12.8 10.3 0.013 15.2 2.8 2.9 2 0 0 2 2 2 0 HSA Transket_pyr PF02779.19 EDO18267.1 - 1.9e-65 219.7 0.0 3.2e-65 218.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EDO18267.1 - 2.7e-57 193.7 0.0 3.7e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component adh_short PF00106.20 EDO18268.1 - 4.9e-27 94.8 0.0 6.8e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EDO18268.1 - 1.8e-16 60.6 0.0 2.4e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EDO18268.1 - 2.7e-08 33.7 0.0 4.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDO18268.1 - 4.4e-05 23.5 0.0 0.00026 21.0 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EDO18268.1 - 9.3e-05 21.9 0.0 0.00073 19.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EDO18268.1 - 0.0033 16.6 0.0 0.15 11.2 0.0 2.5 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 EDO18268.1 - 0.0099 14.7 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EDO18268.1 - 0.034 13.9 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EDO18268.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family Mem_trans PF03547.13 EDO18269.1 - 0.18 10.0 5.3 0.26 9.5 3.7 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF3534 PF12053.3 EDO18269.1 - 1.4 8.8 5.9 16 5.3 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3534) MFS_1 PF07690.11 EDO18270.1 - 9.9e-40 136.3 17.8 9.9e-40 136.3 12.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDO18270.1 - 0.00018 19.8 3.6 0.00027 19.2 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EDO18270.1 - 0.0012 18.5 0.7 3.4 7.5 0.0 3.4 3 0 0 3 3 3 2 MFS_1 like family MFS_3 PF05977.8 EDO18270.1 - 0.021 12.9 4.8 0.039 12.0 3.3 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector SLH PF00395.15 EDO18270.1 - 0.03 14.0 0.8 1.2 8.9 0.1 2.6 2 0 0 2 2 2 0 S-layer homology domain UPF0257 PF06788.8 EDO18270.1 - 0.075 12.2 0.1 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0257) PspC PF04024.7 EDO18270.1 - 1.4 8.4 6.4 0.15 11.5 0.2 2.8 3 1 0 3 3 3 0 PspC domain Ras PF00071.17 EDO18271.1 - 3.8e-59 198.6 0.0 4.5e-59 198.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO18271.1 - 8.5e-18 64.9 0.0 2e-17 63.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EDO18271.1 - 3.4e-10 39.4 0.0 4.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EDO18271.1 - 0.00029 20.0 0.0 0.00048 19.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EDO18271.1 - 0.0004 19.6 0.0 0.00072 18.7 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EDO18271.1 - 0.00056 19.8 0.0 0.001 18.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EDO18271.1 - 0.0051 15.5 0.0 0.0051 15.5 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arch_ATPase PF01637.13 EDO18271.1 - 0.015 14.9 0.0 0.021 14.5 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EDO18271.1 - 0.051 13.8 0.0 0.083 13.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter RNase_Zc3h12a_2 PF14626.1 EDO18271.1 - 0.075 12.8 0.4 0.34 10.7 0.3 2.0 1 1 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Aminoglyc_resit PF10706.4 EDO18271.1 - 0.085 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Aminoglycoside-2''-adenylyltransferase Aminotran_1_2 PF00155.16 EDO18273.1 - 1.1e-62 212.1 0.0 1.2e-62 211.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II EMP70 PF02990.11 EDO18273.1 - 0.088 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 Vac7 PF12751.2 EDO18275.1 - 1.4e-19 70.2 20.4 5.1e-12 45.3 0.0 3.9 3 1 1 4 4 4 2 Vacuolar segregation subunit 7 DSPc PF00782.15 EDO18276.1 - 2.2e-33 114.6 0.1 4.5e-33 113.6 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EDO18276.1 - 0.0032 16.4 0.1 0.0051 15.7 0.1 1.3 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EDO18276.1 - 0.0074 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EDO18276.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Ank_2 PF12796.2 EDO18277.1 - 1e-56 189.1 6.3 1.3e-23 83.1 0.5 3.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EDO18277.1 - 1.4e-34 116.1 2.2 1.1e-08 34.4 0.4 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EDO18277.1 - 9.3e-32 108.3 0.8 1.2e-08 34.9 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO18277.1 - 1.2e-28 96.2 0.2 1.8e-05 24.4 0.0 5.7 5 1 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EDO18277.1 - 2.2e-28 98.1 0.0 1.3e-09 38.3 0.0 4.9 4 1 1 5 5 5 4 Ankyrin repeats (many copies) COX4 PF02936.9 EDO18278.1 - 2.6e-33 114.7 0.1 3e-33 114.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Sec23_trunk PF04811.10 EDO18280.1 - 4e-61 206.4 0.6 1e-60 205.0 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDO18280.1 - 5.1e-20 70.8 2.6 5.5e-20 70.7 0.7 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EDO18280.1 - 5.1e-17 61.1 8.1 9.6e-17 60.2 5.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EDO18280.1 - 8.2e-15 55.0 0.2 1.6e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EDO18280.1 - 1.2e-06 28.1 0.0 2.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Metallopep PF12044.3 EDO18281.1 - 8.8e-169 561.4 0.0 1e-168 561.1 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EDO18281.1 - 6.5e-09 35.7 0.3 2.4e-08 33.9 0.0 2.1 2 0 0 2 2 2 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 EDO18281.1 - 0.045 13.6 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EDO18281.1 - 0.054 14.0 0.1 0.13 12.8 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like 6PF2K PF01591.13 EDO18282.1 - 7.7e-78 260.5 0.1 1.3e-77 259.8 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDO18282.1 - 3.9e-32 111.5 0.7 1.4e-31 109.7 0.1 2.2 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EDO18282.1 - 8.6e-08 32.1 0.0 1.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO18282.1 - 2.8e-07 31.3 0.1 1e-06 29.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain Pox_A28 PF04584.9 EDO18282.1 - 0.0014 18.4 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 Poxvirus A28 family KTI12 PF08433.5 EDO18282.1 - 0.0042 16.3 0.0 0.008 15.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EDO18282.1 - 0.0063 16.8 0.1 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EDO18282.1 - 0.0083 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Hist_deacetyl PF00850.14 EDO18283.1 - 3.2e-92 309.1 0.0 4.3e-92 308.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EDO18283.1 - 2.5e-48 163.8 0.6 3.6e-48 163.3 0.4 1.2 1 0 0 1 1 1 1 Arb2 domain Pkinase PF00069.20 EDO18284.1 - 1.2e-40 139.2 0.1 2.2e-40 138.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18284.1 - 5e-32 110.9 0.0 7.7e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO18284.1 - 0.00013 21.7 0.0 0.061 13.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EDO18284.1 - 0.0002 20.4 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO18284.1 - 0.00032 19.8 0.0 0.00057 19.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.9 EDO18284.1 - 0.061 12.2 0.0 0.25 10.2 0.0 1.9 1 1 1 2 2 2 0 Fructosamine kinase CLTH PF10607.4 EDO18285.1 - 8.8e-31 106.5 1.5 8.8e-31 106.5 1.0 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.10 EDO18285.1 - 0.0014 18.5 0.1 0.0092 15.9 0.0 2.4 2 0 0 2 2 2 1 U-box domain Iso_dh PF00180.15 EDO18286.1 - 1.6e-74 250.9 0.2 2.1e-74 250.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Mem_trans PF03547.13 EDO18287.1 - 1.1 7.4 9.2 1.8 6.7 6.4 1.4 1 0 0 1 1 1 0 Membrane transport protein COG6 PF06419.6 EDO18288.1 - 2e-149 498.6 25.9 2e-149 498.6 18.0 1.6 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 zf-AD PF07776.10 EDO18288.1 - 0.018 15.0 0.1 0.23 11.4 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) KIAA1430 PF13879.1 EDO18288.1 - 9.5 6.7 14.2 0.16 12.3 0.7 3.4 3 0 0 3 3 3 0 KIAA1430 homologue DUF2722 PF10846.3 EDO18289.1 - 3e-67 227.4 20.5 2.6e-66 224.3 14.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) PRA1 PF03208.14 EDO18290.1 - 3.1e-42 143.5 0.9 3.7e-42 143.2 0.6 1.1 1 0 0 1 1 1 1 PRA1 family protein Tic20 PF09685.5 EDO18290.1 - 2.7 8.0 9.7 0.13 12.2 1.2 2.0 1 1 1 2 2 2 0 Tic20-like protein Peptidase_M1 PF01433.15 EDO18291.1 - 4.4e-84 282.8 0.0 6.7e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EDO18291.1 - 8.8e-46 155.0 1.0 1.5e-45 154.2 0.7 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EDO18291.1 - 9.6e-15 54.7 0.0 1.6e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EDO18291.1 - 0.15 12.0 1.9 1 9.3 1.3 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase PH PF00169.24 EDO18292.1 - 2.7e-16 59.6 0.9 6.9e-16 58.3 0.6 1.8 1 0 0 1 1 1 1 PH domain Atrophin-1 PF03154.10 EDO18292.1 - 0.1 10.7 5.1 0.14 10.2 3.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family Glycos_transf_1 PF00534.15 EDO18293.1 - 9.6e-13 47.9 0.0 2.2e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EDO18293.1 - 0.00058 20.0 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 SpoVAD PF07451.6 EDO18293.1 - 0.12 10.7 0.0 0.25 9.7 0.0 1.4 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) R3H PF01424.17 EDO18294.1 - 2.9e-13 49.2 0.0 9.6e-13 47.6 0.0 1.9 2 0 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.12 EDO18294.1 - 8.5e-10 38.3 164.0 2.5e-05 24.1 9.2 11.5 9 2 0 9 9 9 6 NF-X1 type zinc finger Tom22 PF04281.8 EDO18294.1 - 0.47 9.9 3.1 1 8.9 2.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 DUF1253 PF06862.7 EDO18295.1 - 2.9e-161 536.7 15.8 2.9e-161 536.7 11.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1253) DEAD PF00270.24 EDO18295.1 - 1.8e-05 24.3 0.8 0.00062 19.2 0.5 2.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_L31 PF01197.13 EDO18296.1 - 0.059 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L31 DIM1 PF02966.11 EDO18297.1 - 1.4e-68 228.4 0.7 1.6e-68 228.2 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EDO18297.1 - 0.00013 21.5 0.1 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EDO18297.1 - 0.058 13.5 0.8 0.12 12.5 0.5 1.5 1 1 0 1 1 1 0 Thioredoxin-like tRNA-synt_2b PF00587.20 EDO18298.1 - 6e-69 231.0 0.2 1e-68 230.2 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EDO18298.1 - 4.6e-21 74.5 0.7 2.2e-20 72.3 0.0 2.5 2 0 0 2 2 2 1 Anticodon binding domain RRM_1 PF00076.17 EDO18299.1 - 6.8e-14 51.2 0.1 4.2e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO18299.1 - 3e-12 46.3 0.0 4.8e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO18299.1 - 6.9e-08 32.2 0.2 0.016 15.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pex14_N PF04695.8 EDO18299.1 - 0.045 13.7 0.4 0.085 12.9 0.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region VIT1 PF01988.14 EDO18299.1 - 0.56 9.6 2.3 0.93 8.9 1.5 1.4 1 1 0 1 1 1 0 VIT family GTP_EFTU PF00009.22 EDO18300.1 - 2.8e-57 193.2 0.0 3.9e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDO18300.1 - 1.8e-35 121.0 0.0 4.6e-35 119.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDO18300.1 - 2.1e-16 59.7 1.8 2.1e-16 59.7 1.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EDO18300.1 - 0.00012 21.6 0.3 0.00012 21.6 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EDO18300.1 - 0.00068 19.5 0.1 0.0023 17.8 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SieB PF14163.1 EDO18301.1 - 4.8 6.7 12.5 13 5.3 8.7 1.8 1 0 0 1 1 1 0 Superinfection exclusion protein B CIMR PF00878.13 EDO18302.1 - 3.8e-08 33.2 0.9 4.3e-05 23.3 0.0 3.1 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 EDO18302.1 - 4e-05 23.1 0.1 6.9e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Rep_4 PF05797.6 EDO18304.1 - 6.4e-07 28.4 0.0 8.7e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 Yeast trans-acting factor (REP1/REP2) Endonuc-dimeris PF09124.5 EDO18304.1 - 0.11 12.1 0.1 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation DUF3074 PF11274.3 EDO18305.1 - 1.5e-40 138.7 0.5 2.1e-40 138.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Transketolase_N PF00456.16 EDO18306.1 - 9.4e-145 481.5 0.0 1.4e-144 481.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EDO18306.1 - 1.5e-44 151.6 0.0 2.3e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EDO18306.1 - 1.8e-12 47.2 0.0 3.5e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EDO18306.1 - 4.2e-06 25.8 0.0 1.8e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EDO18306.1 - 0.022 14.3 0.1 0.094 12.2 0.0 2.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain LMWPc PF01451.16 EDO18307.1 - 7.4e-42 142.9 0.0 8.4e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Ammonium_transp PF00909.16 EDO18308.1 - 4.8e-126 420.4 27.8 5.5e-126 420.2 19.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.3 EDO18308.1 - 0.028 14.1 7.4 0.84 9.4 0.1 4.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Prefoldin_2 PF01920.15 EDO18310.1 - 2.4e-20 72.2 9.2 2.9e-20 71.9 6.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit FliD_C PF07195.7 EDO18310.1 - 0.024 13.9 3.7 0.049 12.9 2.6 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Sipho_Gp157 PF05565.6 EDO18310.1 - 0.03 13.9 2.8 0.043 13.3 1.6 1.7 1 1 0 1 1 1 0 Siphovirus Gp157 CAP_assoc_N PF14504.1 EDO18310.1 - 0.071 12.8 2.7 0.092 12.4 0.7 1.8 1 1 1 2 2 2 0 CAP-associated N-terminal WXG100 PF06013.7 EDO18310.1 - 0.097 12.6 0.5 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF4515 PF14988.1 EDO18310.1 - 0.29 10.7 7.7 1.8 8.1 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Snapin_Pallidin PF14712.1 EDO18310.1 - 1.7 9.0 6.3 0.44 10.8 0.2 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Rho_Binding PF08912.6 EDO18310.1 - 1.7 8.9 6.6 2.5 8.4 0.1 2.4 2 0 0 2 2 2 0 Rho Binding FlaC_arch PF05377.6 EDO18310.1 - 5.9 6.8 9.1 2.3 8.1 0.6 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Wbp11 PF09429.5 EDO18310.1 - 8.5 6.4 7.4 0.54 10.2 0.3 2.1 2 1 0 2 2 2 0 WW domain binding protein 11 zf-AN1 PF01428.11 EDO18312.1 - 4.2e-11 42.5 13.4 7.4e-11 41.7 9.3 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger tRNA_anti-codon PF01336.20 EDO18312.1 - 0.072 12.9 0.1 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain WLM PF08325.5 EDO18313.1 - 6e-53 179.4 0.0 7.1e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 EDO18313.1 - 0.043 13.6 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF45 INSIG PF07281.7 EDO18314.1 - 4.2e-11 42.5 1.5 6.3e-11 41.9 0.8 1.6 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DUF4131 PF13567.1 EDO18314.1 - 9.8 5.5 7.3 22 4.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Endosulfine PF04667.12 EDO18315.1 - 1.8e-32 111.1 0.1 2.5e-32 110.6 0.1 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Peptidase_M14 PF00246.19 EDO18316.1 - 5.3e-66 223.0 0.2 6.5e-66 222.7 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF4355 PF14265.1 EDO18317.1 - 0.016 15.1 1.1 0.023 14.6 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) MPP6 PF10175.4 EDO18317.1 - 0.07 13.5 0.2 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 M-phase phosphoprotein 6 Tub_2 PF04525.7 EDO18319.1 - 0.022 14.1 0.0 0.022 14.1 0.0 1.0 1 0 0 1 1 1 0 Tubby C 2 Tub_2 PF04525.7 EDO18320.1 - 0.041 13.2 0.0 0.041 13.2 0.0 1.0 1 0 0 1 1 1 0 Tubby C 2 Tub_2 PF04525.7 EDO18321.1 - 0.022 14.1 0.0 0.022 14.1 0.0 1.0 1 0 0 1 1 1 0 Tubby C 2 UPRTase PF14681.1 EDO18322.1 - 4.3e-77 257.9 0.0 5.5e-77 257.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EDO18322.1 - 0.009 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EDO18322.1 - 0.073 12.8 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Tom5 PF10642.4 EDO18323.1 - 1.4e-26 91.8 0.3 1.5e-26 91.7 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Med26 PF08711.6 EDO18324.1 - 9.4e-14 50.6 0.3 2.9e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain PP2C_C PF07830.8 EDO18324.1 - 0.82 9.8 3.3 9.8 6.3 0.0 2.9 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Phasin PF05597.6 EDO18324.1 - 2.6 7.8 9.1 0.14 11.9 2.1 2.1 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3720 PF12517.3 EDO18324.1 - 5.4 7.7 12.3 12 6.6 2.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3720) Ribosom_S12_S23 PF00164.20 EDO18325.1 - 7e-41 138.4 0.6 8.2e-41 138.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 CNH PF00780.17 EDO18326.1 - 2.5e-05 23.8 0.6 0.022 14.1 0.0 2.3 2 0 0 2 2 2 2 CNH domain WD40 PF00400.27 EDO18326.1 - 0.013 15.3 0.5 4.5 7.3 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Acetyltransf_1 PF00583.19 EDO18327.1 - 7e-11 42.0 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EDO18327.1 - 1.7e-05 24.4 0.0 3.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EDO18327.1 - 0.0028 17.8 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EDO18327.1 - 0.008 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDO18327.1 - 0.058 13.2 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LSM14 PF12701.2 EDO18328.1 - 3.2e-24 84.5 1.5 3.2e-24 84.5 0.0 1.8 2 0 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.5 EDO18328.1 - 1.6e-11 44.6 14.7 1.6e-11 44.6 10.2 3.3 3 1 0 3 3 3 1 FDF domain BAF1_ABF1 PF04684.8 EDO18328.1 - 2.6e-05 23.3 19.4 3.5e-05 22.8 13.4 1.2 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor FAM222A PF15258.1 EDO18328.1 - 0.00097 18.4 10.5 0.0012 18.1 7.3 1.2 1 0 0 1 1 1 1 Protein family of FAM222A SM-ATX PF14438.1 EDO18328.1 - 0.059 13.2 0.6 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 Ataxin 2 SM domain Zip PF02535.17 EDO18328.1 - 0.13 11.1 8.3 0.2 10.6 5.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.4 EDO18328.1 - 0.29 9.3 12.1 0.43 8.8 8.4 1.3 1 0 0 1 1 1 0 Transmembrane protein SelP_N PF04592.9 EDO18328.1 - 2.5 7.4 21.1 0.86 8.9 12.8 1.5 1 1 1 2 2 2 0 Selenoprotein P, N terminal region CDC45 PF02724.9 EDO18328.1 - 3.1 5.7 11.3 4.2 5.2 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Aldo_ket_red PF00248.16 EDO18329.1 - 1.3e-42 145.5 0.0 1.5e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MTS PF05175.9 EDO18329.1 - 0.025 13.9 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TruD PF01142.13 EDO18331.1 - 1e-63 215.3 0.8 1.7e-59 201.4 0.0 3.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Nbl1_Borealin_N PF10444.4 EDO18331.1 - 0.031 13.6 0.0 0.095 12.0 0.0 1.8 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal Vfa1 PF08432.5 EDO18331.1 - 1.3 8.9 11.6 0.081 12.9 4.0 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 MOZ_SAS PF01853.13 EDO18332.1 - 8.4e-89 295.8 0.1 1.3e-88 295.2 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EDO18332.1 - 6.8e-22 76.9 0.1 1.5e-21 75.8 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 EDO18332.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Spc97_Spc98 PF04130.8 EDO18332.1 - 0.033 12.5 0.0 0.067 11.5 0.0 1.4 1 0 0 1 1 1 0 Spc97 / Spc98 family PTPA PF03095.10 EDO18333.1 - 4.5e-118 393.7 1.6 5.6e-118 393.4 1.1 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DAGAT PF03982.8 EDO18334.1 - 4.6e-76 255.3 2.5 1.8e-68 230.4 0.1 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase PqiA PF04403.8 EDO18334.1 - 0.024 14.2 0.5 0.044 13.3 0.3 1.4 1 0 0 1 1 1 0 Paraquat-inducible protein A Asp PF00026.18 EDO18335.1 - 3.6e-108 361.5 0.4 4.4e-108 361.2 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EDO18335.1 - 8.3e-11 42.1 0.0 1.3e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EDO18335.1 - 0.00035 21.0 0.1 0.017 15.5 0.0 2.5 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 EDO18335.1 - 0.0012 18.3 0.0 0.011 15.2 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Kinesin PF00225.18 EDO18336.1 - 7.8e-104 346.9 1.3 1.6e-103 345.9 0.9 1.5 1 0 0 1 1 1 1 Kinesin motor domain CENP-Q PF13094.1 EDO18336.1 - 0.01 15.8 4.4 0.01 15.8 3.1 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.1 EDO18336.1 - 0.25 10.2 6.1 0.78 8.6 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Med30 PF11315.3 EDO18336.1 - 2 8.5 8.0 0.76 9.8 2.6 2.4 2 1 1 3 3 3 0 Mediator complex subunit 30 V_ATPase_I PF01496.14 EDO18336.1 - 2.2 5.9 10.5 0.24 9.2 3.1 2.0 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family Methyltransf_15 PF09445.5 EDO18337.1 - 1.2e-57 193.9 0.0 1.8e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EDO18337.1 - 2.1e-06 28.2 0.0 4.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO18337.1 - 8.6e-06 25.7 0.0 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EDO18337.1 - 3.7e-05 23.3 0.0 5.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 EDO18337.1 - 4.1e-05 23.2 0.0 8.4e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO18337.1 - 0.001 19.3 0.0 0.0027 18.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MethyltransfD12 PF02086.10 EDO18337.1 - 0.0036 16.7 0.1 0.0036 16.7 0.1 2.1 3 0 0 3 3 3 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_23 PF13489.1 EDO18337.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF3213 PF11491.3 EDO18337.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3213) Pet20 PF08692.5 EDO18338.1 - 1.3e-27 96.4 4.5 1.6e-14 53.9 0.1 3.2 2 1 1 3 3 3 2 Mitochondrial protein Pet20 DUF3401 PF11881.3 EDO18338.1 - 0.012 15.0 0.5 0.012 15.0 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3401) DUF4038 PF13204.1 EDO18338.1 - 0.036 13.4 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) FAM176 PF14851.1 EDO18338.1 - 3.6 7.2 5.1 0.81 9.3 1.3 1.5 2 0 0 2 2 2 0 FAM176 family DUF3661 PF12400.3 EDO18339.1 - 5.6e-44 149.3 7.1 1e-43 148.5 4.9 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein TRI5 PF06330.6 EDO18339.1 - 0.0096 14.5 0.3 0.015 13.9 0.2 1.2 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) YbbR PF07949.7 EDO18340.1 - 0.054 13.6 1.9 0.36 10.9 1.1 2.4 1 1 0 1 1 1 0 YbbR-like protein Phage_stabilise PF11134.3 EDO18340.1 - 0.063 11.8 0.5 0.06 11.8 0.3 1.2 1 0 0 1 1 1 0 Phage stabilisation protein HATPase_c_3 PF13589.1 EDO18341.1 - 8e-13 48.2 0.2 1.8e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EDO18341.1 - 1.1e-07 31.5 0.0 3e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EDO18341.1 - 0.00016 21.3 0.0 0.0017 17.9 0.1 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EDO18341.1 - 0.024 14.1 0.3 0.073 12.5 0.2 2.0 1 1 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain Apc5 PF12862.2 EDO18342.1 - 2.3e-28 97.8 1.4 2.3e-28 97.8 1.0 3.4 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 5 Clp1 PF06807.9 EDO18343.1 - 1.2e-18 67.5 0.0 1.9e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EDO18343.1 - 1.1e-05 25.1 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EDO18343.1 - 0.00029 20.7 0.2 0.0026 17.6 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EDO18343.1 - 0.0008 18.9 0.0 0.0027 17.1 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EDO18343.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EDO18343.1 - 0.17 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Rhodanese PF00581.15 EDO18344.1 - 4.3e-17 62.4 0.0 1.1e-08 35.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DUF4640 PF15480.1 EDO18345.1 - 0.0018 17.8 6.4 0.011 15.3 4.1 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4640) DUF1436 PF07262.6 EDO18345.1 - 0.076 12.4 0.6 0.13 11.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) DNA_pol_B PF00136.16 EDO18346.1 - 4.3e-94 315.9 1.3 7.2e-94 315.1 0.1 2.0 1 1 1 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EDO18346.1 - 9.2e-19 67.4 2.6 2.9e-09 36.2 0.2 2.8 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EDO18346.1 - 2.1e-14 53.2 10.5 5.8e-14 51.8 7.3 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta TAP_C PF03943.8 EDO18347.1 - 5.2e-15 54.5 0.3 1.6e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.2 EDO18347.1 - 1.6e-07 30.7 7.8 9.9e-06 25.0 2.1 2.9 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EDO18347.1 - 2.3e-06 27.2 0.6 5.9e-06 25.9 0.4 1.6 1 1 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 EDO18347.1 - 0.0019 18.0 5.3 0.44 10.7 0.1 3.8 3 0 0 3 3 3 1 Leucine Rich repeat NTF2 PF02136.15 EDO18347.1 - 0.0034 17.7 1.4 0.19 12.1 1.0 3.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_1 PF00560.28 EDO18347.1 - 3.8 7.9 10.4 47 4.5 1.4 4.6 3 1 1 4 4 4 0 Leucine Rich Repeat Peptidase_S24 PF00717.18 EDO18348.1 - 1.5e-09 37.3 0.0 3.8e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EDO18348.1 - 0.00011 21.7 0.0 0.00037 20.0 0.0 1.8 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Rhodanese PF00581.15 EDO18349.1 - 6.2e-12 45.8 0.0 2.2e-11 44.1 0.0 2.0 1 1 0 1 1 1 1 Rhodanese-like domain zf-C2H2 PF00096.21 EDO18350.1 - 1.9e-13 49.8 13.8 1.4e-06 28.2 2.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO18350.1 - 1.3e-10 40.8 11.7 3.8e-05 23.7 1.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO18350.1 - 3.2e-09 36.6 20.4 5.7e-08 32.6 3.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDO18350.1 - 8.4e-06 25.7 10.5 0.0003 20.8 2.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EDO18350.1 - 1e-05 25.1 5.9 0.0015 18.2 0.6 2.7 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.1 EDO18350.1 - 0.0004 20.1 10.1 0.0027 17.5 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EDO18350.1 - 0.0033 17.5 6.4 0.57 10.4 1.1 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type AD PF09793.4 EDO18350.1 - 0.018 14.8 1.4 0.042 13.6 1.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain GAGA PF09237.6 EDO18350.1 - 0.032 13.8 2.3 0.4 10.3 0.4 2.4 1 1 1 2 2 2 0 GAGA factor PyrI_C PF02748.10 EDO18350.1 - 0.15 11.5 1.9 0.51 9.8 1.3 2.0 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 EDO18350.1 - 0.3 11.2 5.2 1 9.4 3.6 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EDO18350.1 - 0.59 10.2 12.7 1.3 9.1 1.2 3.1 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.1 EDO18350.1 - 1.2 9.5 10.7 8.2 6.8 1.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PAT1 PF09770.4 EDO18351.1 - 0.017 13.4 66.2 0.02 13.1 45.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 EDO18351.1 - 0.28 11.4 5.9 0.42 10.9 4.1 1.3 1 0 0 1 1 1 0 AAA domain DUF605 PF04652.11 EDO18351.1 - 5.6 6.2 38.0 7.3 5.8 26.3 1.1 1 0 0 1 1 1 0 Vta1 like Aldo_ket_red PF00248.16 EDO18352.1 - 3.8e-57 193.2 0.1 4.7e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NDK PF00334.14 EDO18353.1 - 9.6e-56 187.3 0.0 1.1e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF4588 PF15251.1 EDO18354.1 - 3.6e-09 36.9 2.8 9.9e-09 35.5 1.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) 6PF2K PF01591.13 EDO18354.1 - 9.2e-05 21.6 0.7 9.2e-05 21.6 0.5 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase POTRA_2 PF08479.6 EDO18354.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type SUR7 PF06687.7 EDO18355.1 - 6.6e-35 120.5 9.0 8.2e-35 120.2 6.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Jiraiya PF15038.1 EDO18355.1 - 0.005 16.2 1.6 0.056 12.8 1.3 2.2 2 0 0 2 2 2 1 Jiraiya Amastin PF07344.6 EDO18355.1 - 6 6.4 11.5 44 3.6 6.5 2.3 2 0 0 2 2 2 0 Amastin surface glycoprotein Gsf2 PF11055.3 EDO18356.1 - 4.8e-179 594.7 0.2 5.6e-179 594.4 0.1 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 LRR_6 PF13516.1 EDO18359.1 - 0.63 10.2 0.0 0.63 10.2 0.0 9.5 11 1 1 12 12 12 0 Leucine Rich repeat hDGE_amylase PF14701.1 EDO18360.1 - 1.4e-174 580.9 0.5 2.7e-174 580.0 0.3 1.5 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EDO18360.1 - 1.8e-124 415.2 0.0 2.8e-124 414.5 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EDO18360.1 - 2.1e-77 259.8 0.0 4.4e-77 258.7 0.0 1.6 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EDO18360.1 - 1e-21 76.5 0.6 3e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EDO18360.1 - 6.5e-07 29.0 0.1 0.00025 20.5 0.2 2.5 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Glycos_transf_2 PF00535.21 EDO18361.1 - 1.3e-29 103.0 0.0 2e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EDO18361.1 - 6.3e-08 32.0 0.0 9.6e-08 31.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EDO18361.1 - 2e-07 31.0 0.0 2.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 LSM PF01423.17 EDO18362.1 - 4.9e-18 64.4 0.3 5.6e-18 64.2 0.2 1.0 1 0 0 1 1 1 1 LSM domain Sec23_trunk PF04811.10 EDO18363.1 - 7.7e-74 248.1 0.0 1.1e-73 247.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDO18363.1 - 2.3e-33 113.7 0.1 4.7e-33 112.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EDO18363.1 - 1.6e-29 102.2 0.7 4.3e-29 100.8 0.5 1.8 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EDO18363.1 - 2.2e-14 52.7 9.9 4.1e-14 51.8 6.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EDO18363.1 - 4.8e-11 42.1 0.0 1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-MIZ PF02891.15 EDO18363.1 - 0.31 10.5 2.8 0.67 9.5 1.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger HDA2-3 PF11496.3 EDO18364.1 - 5.9e-86 287.9 3.4 5.9e-86 287.9 2.3 3.0 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 DUF869 PF05911.6 EDO18364.1 - 0.0035 15.6 22.5 0.0048 15.1 15.6 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) KIP1 PF07765.7 EDO18364.1 - 0.13 12.0 2.7 0.39 10.6 0.5 2.7 3 0 0 3 3 3 0 KIP1-like protein Reo_sigmaC PF04582.7 EDO18364.1 - 1.2 8.2 4.9 0.43 9.7 1.1 1.9 1 1 0 2 2 2 0 Reovirus sigma C capsid protein TBPIP PF07106.8 EDO18364.1 - 2.7 7.4 34.1 0.1 12.1 10.4 3.3 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Baculo_PEP_C PF04513.7 EDO18364.1 - 4.7 7.0 13.2 0.11 12.2 2.9 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EDO18364.1 - 6.7 6.6 8.4 7.1 6.5 1.7 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) PspA_IM30 PF04012.7 EDO18364.1 - 7.8 5.7 20.5 10 5.3 7.7 2.5 1 1 2 3 3 3 0 PspA/IM30 family WD40 PF00400.27 EDO18365.1 - 1.5e-19 69.0 8.6 4.1e-11 42.3 1.2 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Plasmid_killer PF05015.8 EDO18365.1 - 0.036 14.2 0.1 0.057 13.5 0.1 1.4 1 1 0 1 1 1 0 Plasmid maintenance system killer protein eIF2A PF08662.6 EDO18365.1 - 0.04 13.6 0.4 0.068 12.8 0.2 1.5 1 1 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EDO18366.1 - 5e-29 99.1 12.4 1.5e-08 34.2 0.2 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EDO18366.1 - 0.0015 18.2 0.1 0.021 14.5 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Prenyltrans PF00432.16 EDO18367.1 - 4.4e-61 202.0 3.7 3.3e-13 48.9 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EDO18367.1 - 6.4e-26 90.9 0.0 6.3e-14 52.3 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EDO18367.1 - 1.4e-07 31.5 0.0 0.017 15.1 0.0 3.2 1 1 2 3 3 3 2 Prenyltransferase-like DNA_pol_E_B PF04042.11 EDO18368.1 - 2.3e-52 177.2 0.3 4.1e-52 176.4 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pepsin-I3 PF06394.8 EDO18368.1 - 0.0073 15.9 0.1 0.41 10.3 0.1 2.5 2 0 0 2 2 2 1 Pepsin inhibitor-3-like repeated domain NBP1 PF08537.5 EDO18369.1 - 2e-144 480.7 17.2 2.2e-144 480.6 11.9 1.0 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 SlyX PF04102.7 EDO18369.1 - 0.06 13.7 0.7 0.24 11.8 0.5 2.1 1 0 0 1 1 1 0 SlyX DUF3373 PF11853.3 EDO18369.1 - 0.087 11.3 0.2 0.11 10.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) USP8_interact PF08941.5 EDO18369.1 - 2 7.6 5.7 0.56 9.5 0.8 2.1 2 0 0 2 2 2 0 USP8 interacting IncA PF04156.9 EDO18369.1 - 3.7 7.0 10.0 1.6 8.3 5.1 1.7 1 1 0 1 1 1 0 IncA protein AAA PF00004.24 EDO18370.1 - 4.3e-44 149.9 0.0 7.7e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EDO18370.1 - 4.9e-31 106.4 0.0 7.3e-30 102.6 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EDO18370.1 - 2.1e-22 78.7 1.6 7.4e-22 77.0 0.8 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EDO18370.1 - 2e-06 28.6 0.1 1.3e-05 25.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EDO18370.1 - 2.1e-06 27.8 0.1 0.00065 19.8 0.1 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDO18370.1 - 9.5e-06 24.8 0.0 1.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EDO18370.1 - 9.9e-06 25.3 0.0 5.8e-05 22.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDO18370.1 - 1.3e-05 25.1 0.1 4.5e-05 23.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EDO18370.1 - 2.1e-05 24.0 0.0 5.6e-05 22.6 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein DUF815 PF05673.8 EDO18370.1 - 2.6e-05 23.3 0.0 0.00063 18.7 0.0 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EDO18370.1 - 2.6e-05 24.2 0.1 0.00015 21.8 0.0 2.2 2 1 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.1 EDO18370.1 - 5.9e-05 22.5 0.2 0.056 12.8 0.1 2.4 1 1 1 2 2 2 2 AAA domain RNA_helicase PF00910.17 EDO18370.1 - 8.9e-05 22.6 0.3 0.0075 16.4 0.0 3.2 4 0 0 4 4 3 1 RNA helicase AAA_2 PF07724.9 EDO18370.1 - 0.00017 21.5 0.1 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EDO18370.1 - 0.00026 19.8 0.0 0.00044 19.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EDO18370.1 - 0.00034 20.5 0.1 0.0014 18.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EDO18370.1 - 0.0038 17.5 0.6 0.014 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EDO18370.1 - 0.004 16.2 0.1 0.12 11.4 0.0 2.7 1 1 2 3 3 3 1 Zeta toxin AAA_24 PF13479.1 EDO18370.1 - 0.013 15.1 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDO18370.1 - 0.019 14.7 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EDO18370.1 - 0.024 13.7 0.1 4.5 6.3 0.0 2.3 1 1 1 2 2 2 0 KaiC NACHT PF05729.7 EDO18370.1 - 0.026 14.1 0.0 0.59 9.7 0.0 2.2 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EDO18370.1 - 0.028 13.5 0.0 0.063 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 EDO18370.1 - 0.029 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Torsin Arch_ATPase PF01637.13 EDO18370.1 - 0.036 13.7 1.6 0.44 10.2 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase PhoH PF02562.11 EDO18370.1 - 0.036 13.2 0.0 0.086 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EDO18370.1 - 0.066 12.0 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 EDO18370.1 - 0.068 13.4 0.4 1 9.6 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Cytidylate_kin2 PF13189.1 EDO18370.1 - 0.075 12.9 0.9 0.83 9.5 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family Sigma54_activat PF00158.21 EDO18370.1 - 0.081 12.3 0.0 0.44 10.0 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EDO18370.1 - 0.084 12.9 0.0 0.21 11.6 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EDO18370.1 - 0.098 12.6 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_21 PF13304.1 EDO18370.1 - 0.37 10.7 2.7 2.2 8.1 0.0 2.8 2 1 1 3 3 3 0 AAA domain KTI12 PF08433.5 EDO18370.1 - 1.7 7.7 5.2 6 5.9 0.0 2.9 2 2 0 2 2 2 0 Chromatin associated protein KTI12 Pyridox_oxidase PF01243.15 EDO18371.1 - 2e-17 62.9 0.0 1e-16 60.7 0.0 2.0 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EDO18371.1 - 0.0081 15.9 0.0 0.84 9.4 0.0 2.1 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Aa_trans PF01490.13 EDO18373.1 - 0.16 10.4 1.1 0.37 9.2 0.7 1.5 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein WD40 PF00400.27 EDO18374.1 - 3.3e-06 26.7 1.7 0.0018 18.1 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_3 PF13570.1 EDO18374.1 - 0.066 13.5 0.1 48 4.4 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain PQQ PF01011.16 EDO18374.1 - 0.22 11.1 1.1 31 4.3 0.2 3.5 3 0 0 3 3 3 0 PQQ enzyme repeat Ribosomal_S14 PF00253.16 EDO18375.1 - 4.5e-17 61.1 0.1 7e-17 60.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ras PF00071.17 EDO18376.1 - 1.4e-53 180.6 0.0 1.7e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO18376.1 - 2.4e-16 60.2 0.0 4.3e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO18376.1 - 9.7e-08 31.4 0.0 1.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO18376.1 - 0.00011 21.7 0.1 0.00046 19.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDO18376.1 - 0.0036 16.4 0.0 0.0048 16.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EDO18377.1 - 2.4e-55 186.3 0.0 2.9e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO18377.1 - 2.6e-16 60.2 0.0 4e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO18377.1 - 4.8e-07 29.1 0.0 6.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO18377.1 - 0.0026 17.2 0.0 0.0068 15.8 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EDO18377.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EDO18377.1 - 0.11 12.0 0.1 5.9 6.3 0.0 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EDO18377.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Fmp27 PF10344.4 EDO18378.1 - 5.4e-201 669.6 42.2 1.1e-200 668.5 29.2 1.6 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.4 EDO18378.1 - 3e-122 408.4 10.4 6.2e-122 407.4 7.2 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 EDO18378.1 - 3.6e-106 355.7 17.3 3.5e-79 266.8 7.6 2.6 1 1 1 2 2 2 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 EDO18378.1 - 4.9e-57 192.2 2.8 1.2e-56 190.9 0.2 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EDO18378.1 - 4.4e-54 182.4 2.3 4.4e-54 182.4 1.6 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EDO18378.1 - 9.2e-34 115.9 1.0 6.6e-33 113.2 0.0 3.3 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain RRM_6 PF14259.1 EDO18379.1 - 2.1e-07 30.8 0.0 3.5e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO18379.1 - 4.8e-07 29.3 0.0 8.7e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 EDO18380.1 - 1.7e-71 240.4 1.3 2.3e-71 239.9 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18380.1 - 5.3e-29 101.0 0.1 5.8e-28 97.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 EDO18381.1 - 4.2e-17 62.3 0.7 3.9e-11 43.0 0.1 2.7 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.16 EDO18381.1 - 1e-11 44.3 0.0 3.2e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GTP_EFTU PF00009.22 EDO18382.1 - 1.3e-38 132.2 0.0 2.3e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EDO18382.1 - 3.1e-36 123.2 0.3 7e-36 122.1 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EDO18382.1 - 9.5e-08 32.0 0.3 3.9e-07 30.0 0.2 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO18382.1 - 0.0063 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDO18382.1 - 0.12 12.2 0.1 0.82 9.4 0.0 2.3 3 0 0 3 3 3 0 Dynamin family Carn_acyltransf PF00755.15 EDO18383.1 - 8.3e-79 265.2 0.1 1.1e-64 218.6 0.1 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Ribosomal_S7 PF00177.16 EDO18384.1 - 9.2e-40 135.6 1.9 1.3e-39 135.1 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ATP-synt_ab PF00006.20 EDO18385.1 - 6.7e-63 212.0 0.0 1e-62 211.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDO18385.1 - 1.5e-26 93.1 0.2 2.5e-26 92.3 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDO18385.1 - 2.8e-22 78.6 1.8 2.8e-22 78.6 1.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 EDO18385.1 - 0.0023 17.0 0.2 0.0038 16.3 0.1 1.4 1 0 0 1 1 1 1 KaiC MobB PF03205.9 EDO18385.1 - 0.0037 16.9 0.1 0.56 9.9 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EDO18385.1 - 0.0037 16.6 0.0 0.01 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EDO18385.1 - 0.02 13.7 0.5 0.52 9.1 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 EDO18385.1 - 0.022 14.4 0.2 0.074 12.7 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EDO18385.1 - 0.051 13.5 0.4 0.19 11.7 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EDO18385.1 - 0.057 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 EDO18385.1 - 0.06 13.5 0.0 0.63 10.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO18385.1 - 0.11 12.6 0.0 0.36 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDO18385.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EDO18385.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase P5CR_dimer PF14748.1 EDO18386.1 - 8.2e-33 112.6 0.1 1.5e-32 111.7 0.1 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EDO18386.1 - 1.4e-11 44.6 0.3 3.3e-11 43.4 0.2 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EDO18386.1 - 0.0076 15.9 0.3 0.016 14.9 0.2 1.7 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4088 PF13317.1 EDO18386.1 - 0.081 12.2 0.0 0.2 10.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4088) Med17 PF10156.4 EDO18387.1 - 1.3e-153 511.6 15.6 1.6e-153 511.3 10.8 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PfkB PF00294.19 EDO18388.1 - 9.4e-69 231.8 1.8 1.2e-68 231.5 1.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EDO18388.1 - 1e-05 24.8 0.0 1.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase G-alpha PF00503.15 EDO18389.1 - 3.7e-110 368.2 13.9 3.7e-110 368.2 9.6 2.0 1 1 1 2 2 2 1 G-protein alpha subunit Arf PF00025.16 EDO18389.1 - 4.7e-13 48.7 4.8 9.5e-10 37.9 0.1 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family Miro PF08477.8 EDO18389.1 - 4.6e-05 23.9 0.5 0.35 11.3 0.0 3.1 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 EDO18389.1 - 0.0088 15.5 0.1 0.02 14.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EDO18389.1 - 0.016 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Ras PF00071.17 EDO18389.1 - 0.13 11.6 3.2 16 4.8 0.0 3.6 3 1 0 3 3 3 0 Ras family Macoilin PF09726.4 EDO18389.1 - 9 4.4 19.1 11 4.1 13.2 1.1 1 0 0 1 1 1 0 Transmembrane protein SNAP PF14938.1 EDO18390.1 - 2.3e-108 361.6 10.7 2.6e-108 361.4 7.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EDO18390.1 - 2.2e-05 24.3 13.7 0.054 13.4 0.4 3.9 2 1 1 4 4 4 2 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EDO18390.1 - 4.7e-05 23.0 1.2 8.2e-05 22.1 0.5 1.7 1 1 0 2 2 2 1 Foie gras liver health family 1 DUF2225 PF09986.4 EDO18390.1 - 0.00082 18.8 6.9 0.33 10.3 2.4 3.0 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 EDO18390.1 - 0.00086 19.6 10.0 1.3 9.6 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDO18390.1 - 0.0015 18.8 10.8 0.58 10.5 0.3 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat Spatacsin_C PF14649.1 EDO18390.1 - 0.15 10.9 5.6 0.15 10.8 1.6 2.2 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_7 PF13176.1 EDO18390.1 - 0.27 11.1 6.0 1.9 8.4 0.1 4.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 EDO18390.1 - 0.38 10.4 16.1 0.94 9.1 1.9 3.8 1 1 2 3 3 3 0 TPR repeat Apc3 PF12895.2 EDO18390.1 - 5.3 7.2 10.6 8.1 6.6 0.5 3.2 2 2 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Yippee-Mis18 PF03226.9 EDO18391.1 - 5.6e-18 64.7 3.7 7.5e-18 64.3 2.6 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 EDO18391.1 - 0.11 12.5 1.8 1.2 9.1 0.2 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Evr1_Alr PF04777.8 EDO18391.1 - 0.17 11.8 0.1 0.17 11.8 0.1 1.9 1 1 1 2 2 2 0 Erv1 / Alr family DUF2757 PF10955.3 EDO18391.1 - 9.3 6.5 7.0 1.6 9.0 0.1 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2757) Myotub-related PF06602.9 EDO18392.1 - 1.6e-125 418.5 4.6 2.1e-125 418.1 3.2 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EDO18392.1 - 0.008 16.4 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family GRAM PF02893.15 EDO18392.1 - 0.011 15.1 0.0 0.037 13.5 0.0 1.8 1 0 0 1 1 1 0 GRAM domain CMD PF02627.15 EDO18393.1 - 3.2e-06 26.8 0.0 8e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family EF-hand_4 PF12763.2 EDO18394.1 - 2.5e-34 117.1 3.5 4.7e-10 39.1 0.0 4.4 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 EDO18394.1 - 4.3e-10 39.1 0.0 1e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 EDO18394.1 - 8.9e-10 38.5 0.0 0.019 15.0 0.0 4.2 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EDO18394.1 - 3.1e-08 32.3 0.1 0.0089 15.2 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 EDO18394.1 - 1.5e-06 27.5 0.0 0.25 11.3 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EDO18394.1 - 0.0021 17.6 0.0 1.8 8.2 0.0 3.7 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.1 EDO18394.1 - 0.022 14.0 0.0 6.4 6.3 0.0 2.8 2 0 0 2 2 2 0 EF hand Filament PF00038.16 EDO18394.1 - 2 7.7 56.6 0.025 14.0 25.3 3.5 2 1 1 3 3 3 0 Intermediate filament protein VanZ PF04892.7 EDO18395.1 - 1.5e-05 24.9 0.3 2.7e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 VanZ like family Mss4 PF04421.8 EDO18395.1 - 0.089 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Mss4 protein Ribosomal_S7 PF00177.16 EDO18396.1 - 1.4e-32 112.2 0.1 4.9e-32 110.5 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e TCL1_MTCP1 PF01840.12 EDO18396.1 - 0.13 11.7 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 TCL1/MTCP1 family PPP4R2 PF09184.6 EDO18397.1 - 9e-84 281.4 23.1 9e-84 281.4 16.0 1.9 1 1 1 2 2 2 1 PPP4R2 Tom37_C PF11801.3 EDO18397.1 - 1.1 9.1 6.0 11 5.9 3.2 2.5 2 0 0 2 2 2 0 Tom37 C-terminal domain BUD22 PF09073.5 EDO18397.1 - 2.3 7.2 23.8 3.5 6.6 16.5 1.3 1 0 0 1 1 1 0 BUD22 Peptidase_M16_C PF05193.16 EDO18398.1 - 3e-20 72.6 0.1 6.7e-20 71.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDO18398.1 - 1.2e-16 60.8 0.8 2.2e-16 59.9 0.6 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M20 PF01546.23 EDO18400.1 - 1.3e-22 80.2 0.0 2.1e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDO18400.1 - 5.6e-15 55.0 0.0 1.9e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase dimerisation domain Transp_cyt_pur PF02133.10 EDO18401.1 - 6.7e-131 436.8 24.0 8e-131 436.6 16.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sod_Cu PF00080.15 EDO18402.1 - 2.3e-40 138.0 3.5 2.7e-40 137.8 2.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CTP_synth_N PF06418.9 EDO18403.1 - 1e-121 405.3 1.3 1.3e-121 404.8 0.9 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EDO18403.1 - 5.2e-57 192.3 0.1 7.9e-57 191.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDO18403.1 - 1.2e-05 24.8 0.0 3.1e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 EDO18403.1 - 0.0036 16.7 0.0 0.006 16.0 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Scramblase PF03803.10 EDO18404.1 - 4.1e-69 232.0 0.1 8.9e-67 224.3 0.0 2.0 1 1 0 1 1 1 1 Scramblase SAC3_GANP PF03399.11 EDO18405.1 - 5.6e-56 189.3 11.5 5.6e-56 189.3 8.0 1.5 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EDO18405.1 - 2.3e-10 40.3 4.0 1.2e-09 38.0 2.8 2.1 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 PCI PF01399.22 EDO18405.1 - 9.7e-05 22.6 1.0 9.7e-05 22.6 0.7 2.5 2 1 0 2 2 2 1 PCI domain PX PF00787.19 EDO18406.1 - 6.4e-05 22.7 1.1 0.00016 21.4 0.1 2.1 2 0 0 2 2 2 1 PX domain DUF4434 PF14488.1 EDO18406.1 - 0.022 14.5 0.0 0.08 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) ZapA PF05164.8 EDO18406.1 - 0.032 14.1 0.1 0.07 13.1 0.1 1.5 1 0 0 1 1 1 0 Cell division protein ZapA Aldo_ket_red PF00248.16 EDO18407.1 - 1.5e-50 171.6 0.0 1.9e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.22 EDO18408.1 - 1.7e-74 245.5 3.5 5.4e-25 86.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF500 PF04366.7 EDO18408.1 - 0.0017 17.8 0.6 0.0032 16.8 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) PGM_PMM_I PF02878.11 EDO18410.1 - 4.4e-17 61.8 0.0 1.7e-09 37.3 0.0 2.6 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EDO18410.1 - 3e-13 49.9 0.0 1.1e-12 48.1 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EDO18410.1 - 1.8e-11 43.8 0.1 6e-11 42.1 0.1 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Mitochondr_Som1 PF11093.3 EDO18411.1 - 2.4e-27 94.5 0.8 2.7e-27 94.4 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 RAMP PF04901.8 EDO18411.1 - 0.056 13.1 0.2 0.065 12.9 0.1 1.1 1 0 0 1 1 1 0 Receptor activity modifying family Colipase-like PF15083.1 EDO18411.1 - 0.092 12.6 0.9 0.11 12.4 0.6 1.2 1 0 0 1 1 1 0 Colipase-like Lyase_1 PF00206.15 EDO18412.1 - 4.1e-116 387.5 0.1 5.3e-116 387.1 0.1 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EDO18412.1 - 3.1e-25 87.9 0.0 1.1e-24 86.2 0.0 1.9 2 0 0 2 2 2 1 Fumarase C C-terminus Peptidase_S8 PF00082.17 EDO18413.1 - 1.1e-55 188.7 4.7 1.1e-55 188.7 3.3 2.3 2 1 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EDO18413.1 - 2.2e-10 40.9 1.7 4e-10 40.1 0.3 2.2 2 0 0 2 2 2 1 Peptidase inhibitor I9 DUF3441 PF11923.3 EDO18413.1 - 0.066 12.8 0.3 0.2 11.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) Collagen PF01391.13 EDO18413.1 - 0.11 11.9 17.5 17 5.0 12.2 2.6 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Kinesin PF00225.18 EDO18414.1 - 2.9e-94 315.5 19.0 8.7e-62 208.7 5.6 3.8 4 1 0 4 4 4 2 Kinesin motor domain DUF4164 PF13747.1 EDO18414.1 - 0.13 12.4 0.1 0.13 12.4 0.1 4.0 3 2 1 4 4 4 0 Domain of unknown function (DUF4164) IncA PF04156.9 EDO18414.1 - 1.1 8.8 30.1 1.8 8.1 0.1 4.2 3 1 0 4 4 4 0 IncA protein DNA_ligase_A_M PF01068.16 EDO18415.1 - 2.4e-44 151.1 0.0 6.3e-44 149.7 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EDO18415.1 - 1.6e-16 60.6 0.0 2.5e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus BRCT PF00533.21 EDO18415.1 - 2.2e-10 40.5 2.7 3.2e-05 23.9 0.0 3.3 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EDO18415.1 - 0.0024 17.6 0.2 0.63 9.7 0.0 2.7 2 1 0 2 2 2 2 mRNA capping enzyme, catalytic domain DNA_ligase_A_C PF04679.10 EDO18415.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region TPR_11 PF13414.1 EDO18416.1 - 1.3e-24 85.6 6.1 1.1e-17 63.4 1.2 3.0 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EDO18416.1 - 5e-18 63.8 10.0 7e-06 25.4 0.2 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDO18416.1 - 6.5e-18 63.1 1.1 6.1e-05 22.6 0.1 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDO18416.1 - 3.8e-09 36.0 4.6 0.0012 18.8 0.1 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO18416.1 - 4.9e-07 29.5 3.4 8.8e-05 22.3 0.3 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO18416.1 - 1e-05 26.0 0.1 0.056 14.1 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EDO18416.1 - 1.5e-05 25.2 0.0 1.2 9.9 0.0 4.0 3 1 2 5 5 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDO18416.1 - 4.7e-05 23.6 0.9 0.1 12.9 0.1 3.2 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO18416.1 - 0.001 18.6 9.2 0.46 10.3 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO18416.1 - 0.0079 15.9 0.1 0.52 10.2 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat PSD4 PF07631.6 EDO18416.1 - 0.0088 16.4 0.4 4.9 7.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1592) ChAPs PF09295.5 EDO18416.1 - 0.1 11.3 2.7 0.12 11.1 1.1 1.7 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 EDO18416.1 - 0.19 12.2 5.9 14 6.3 0.0 3.9 5 0 0 5 5 3 0 Tetratricopeptide repeat HABP4_PAI-RBP1 PF04774.10 EDO18416.1 - 4.5 7.8 7.8 0.12 12.8 0.4 2.1 3 0 0 3 3 2 0 Hyaluronan / mRNA binding family HlyIII PF03006.15 EDO18417.1 - 4.9e-52 176.5 18.8 6.6e-52 176.1 13.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF613 PF04764.7 EDO18417.1 - 0.065 13.1 0.1 0.099 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF613) DUF3671 PF12420.3 EDO18417.1 - 4.3 7.3 9.5 76 3.3 6.6 2.8 1 1 0 1 1 1 0 Protein of unknown function DUF998 PF06197.8 EDO18417.1 - 6.3 6.0 13.5 1.7 7.9 5.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF998) Pkinase PF00069.20 EDO18418.1 - 1.8e-51 174.8 0.4 5e-51 173.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18418.1 - 4.8e-23 81.5 0.0 1.1e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DEAD PF00270.24 EDO18419.1 - 5.7e-48 162.5 0.3 1.6e-46 157.8 0.0 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO18419.1 - 2.5e-22 78.5 0.0 4.8e-21 74.4 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EDO18419.1 - 1.1e-20 73.2 6.4 1.1e-20 73.2 4.5 2.8 3 0 0 3 3 3 1 DBP10CT (NUC160) domain Inositol_P PF00459.20 EDO18420.1 - 1.1e-53 182.2 0.0 4e-53 180.4 0.0 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family Git3 PF11710.3 EDO18421.1 - 5.7e-78 261.1 15.6 1.2e-77 260.0 10.8 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EDO18421.1 - 4.8e-32 109.5 3.4 1.5e-31 107.9 2.3 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term PseudoU_synth_2 PF00849.17 EDO18422.1 - 6.5e-32 110.6 0.5 1.2e-31 109.8 0.0 1.6 2 0 0 2 2 2 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.17 EDO18422.1 - 1.5e-16 59.8 0.0 3.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region NARP1 PF12569.3 EDO18423.1 - 3.5e-118 395.5 27.9 2.8e-84 283.7 4.8 3.2 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 EDO18423.1 - 3e-19 69.1 0.0 0.00026 21.5 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EDO18423.1 - 5.3e-17 60.3 2.6 0.0015 18.2 0.0 8.2 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EDO18423.1 - 4.3e-16 58.9 0.8 0.009 16.3 0.0 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDO18423.1 - 9.5e-15 53.7 0.0 0.0097 16.4 0.0 7.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDO18423.1 - 4.9e-14 51.7 2.7 0.026 14.1 0.1 5.6 4 1 0 5 5 5 4 TPR repeat TPR_12 PF13424.1 EDO18423.1 - 1.4e-08 34.5 2.7 0.049 13.5 0.0 5.3 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO18423.1 - 4.5e-08 32.3 10.1 0.1 12.4 0.1 7.6 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDO18423.1 - 3.3e-07 29.9 3.7 1.4 9.3 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO18423.1 - 9.9e-07 28.8 14.0 0.055 13.6 0.0 6.1 6 1 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EDO18423.1 - 5e-06 25.8 11.2 0.017 14.7 0.0 6.1 8 0 0 8 8 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDO18423.1 - 8.7e-06 25.5 3.2 0.052 13.4 0.1 4.3 4 0 0 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EDO18423.1 - 0.00038 20.7 5.4 0.3 11.6 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EDO18423.1 - 0.0012 18.5 0.1 1.4 8.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR_2 PF13041.1 EDO18423.1 - 0.084 12.8 0.1 0.92 9.5 0.0 2.8 2 0 0 2 2 2 0 PPR repeat family Bud13 PF09736.4 EDO18423.1 - 9.4 6.4 15.0 0.6 10.3 6.4 1.9 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex HLH PF00010.21 EDO18424.1 - 3.1e-15 55.5 0.0 5.1e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Phage_connect_1 PF05135.8 EDO18424.1 - 0.034 14.3 1.2 0.098 12.8 0.2 2.0 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein Syntaxin_2 PF14523.1 EDO18424.1 - 0.072 13.1 2.6 0.31 11.1 0.6 2.1 2 0 0 2 2 2 0 Syntaxin-like protein SIR2 PF02146.12 EDO18425.1 - 2.5e-66 222.7 0.0 6.1e-66 221.5 0.0 1.7 2 0 0 2 2 2 1 Sir2 family DUF592 PF04574.8 EDO18425.1 - 1.9e-63 212.6 3.1 3.8e-63 211.6 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EDO18425.1 - 0.0046 16.7 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain zf-met PF12874.2 EDO18426.1 - 3.4e-06 27.0 1.9 3.4e-06 27.0 1.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EDO18426.1 - 0.021 14.9 0.9 0.021 14.9 0.6 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 EDO18426.1 - 0.068 12.7 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 U1 zinc finger Nuf2 PF03800.9 EDO18427.1 - 2.9e-45 153.8 0.1 2.9e-45 153.8 0.0 2.9 3 0 0 3 3 3 1 Nuf2 family Reo_sigmaC PF04582.7 EDO18427.1 - 5.2 6.1 17.5 2.4 7.2 1.6 2.8 2 1 2 4 4 4 0 Reovirus sigma C capsid protein PAPS_reduct PF01507.14 EDO18430.1 - 4.7e-31 107.9 0.0 6.5e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CHCH PF06747.8 EDO18431.1 - 5.8e-05 22.9 0.4 7.8e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EDO18431.1 - 0.0015 18.2 0.9 0.0018 17.9 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Sdh5 PF03937.11 EDO18432.1 - 8.6e-25 86.2 0.5 1.3e-24 85.6 0.4 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase EndoU_bacteria PF14436.1 EDO18432.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial EndoU nuclease HhH-GPD PF00730.20 EDO18433.1 - 2.4e-11 43.8 0.0 2.3e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein DUF4467 PF14729.1 EDO18433.1 - 0.037 14.3 1.1 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) BSD PF03909.12 EDO18434.1 - 4.2e-13 48.8 0.3 4.2e-13 48.8 0.2 2.6 3 0 0 3 3 3 1 BSD domain DUF1890 PF09001.6 EDO18434.1 - 0.2 11.6 0.0 0.2 11.6 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1890) UCH PF00443.24 EDO18435.1 - 7.2e-68 228.6 0.6 7.2e-68 228.6 0.4 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO18435.1 - 6.9e-29 101.2 0.2 6.9e-29 101.2 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EDO18435.1 - 3.2e-07 30.6 0.0 6.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Hyaluronidase_1 PF07212.6 EDO18435.1 - 0.015 14.2 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Hyaluronidase protein (HylP) TcdB_N PF12918.2 EDO18435.1 - 0.058 13.4 3.1 5 7.2 0.0 3.1 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Zn-ribbon_8 PF09723.5 EDO18435.1 - 0.13 12.2 5.3 0.15 11.9 0.8 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-MIZ PF02891.15 EDO18435.1 - 0.16 11.4 5.3 0.39 10.2 3.7 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Acetyltransf_1 PF00583.19 EDO18436.1 - 4.3e-09 36.2 0.0 6.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EDO18436.1 - 1.3e-08 34.9 0.0 1.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EDO18436.1 - 0.00064 19.6 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO18436.1 - 0.003 17.3 0.0 0.035 13.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EDO18436.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EDO18436.1 - 0.044 13.8 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FTR1 PF03239.9 EDO18437.1 - 7.3e-99 330.5 7.1 1.1e-98 330.0 4.9 1.2 1 0 0 1 1 1 1 Iron permease FTR1 family PAP2 PF01569.16 EDO18438.1 - 2.7e-06 27.0 5.8 2.7e-06 27.0 4.1 3.1 2 2 0 2 2 2 1 PAP2 superfamily Glyco_transf_20 PF00982.16 EDO18440.1 - 3.1e-138 461.2 6.8 4.9e-138 460.5 4.7 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EDO18440.1 - 2.3e-84 281.9 0.0 3.5e-84 281.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Cohesin_load PF10345.4 EDO18441.1 - 1.6e-163 545.1 36.5 1.8e-163 545.0 25.3 1.0 1 0 0 1 1 1 1 Cohesin loading factor Hormone_3 PF00159.13 EDO18441.1 - 1.5 8.9 3.6 3.5 7.7 0.2 2.8 3 0 0 3 3 3 0 Pancreatic hormone peptide TBP PF00352.16 EDO18442.1 - 7.5e-70 230.3 0.1 4.5e-35 118.8 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EDO18442.1 - 0.00015 21.7 0.2 0.66 10.0 0.0 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF3378) Metallophos PF00149.23 EDO18443.1 - 6.9e-41 139.8 0.2 8.6e-41 139.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EDO18443.1 - 0.00016 21.5 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain KaiC PF06745.8 EDO18444.1 - 6.8e-09 35.1 0.1 2.3e-08 33.4 0.1 2.0 1 1 0 1 1 1 1 KaiC Rad51 PF08423.6 EDO18444.1 - 1.9e-07 30.2 0.0 6.1e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EDO18444.1 - 4.1e-06 26.3 0.0 8.3e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EDO18444.1 - 6e-05 22.7 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO18444.1 - 8.4e-05 22.7 0.0 0.00037 20.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EDO18444.1 - 0.00046 19.9 1.0 0.00077 19.2 0.1 1.8 2 0 0 2 2 2 1 Archaeal ATPase DnaB_C PF03796.10 EDO18444.1 - 0.001 18.0 0.0 0.0037 16.1 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Pox_MCEL PF03291.11 EDO18444.1 - 0.0015 17.4 0.9 0.0029 16.5 0.6 1.5 1 0 0 1 1 1 1 mRNA capping enzyme RecA PF00154.16 EDO18444.1 - 0.0043 16.1 0.1 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein T2SE PF00437.15 EDO18444.1 - 0.006 15.5 0.3 0.9 8.3 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_11 PF13086.1 EDO18444.1 - 0.014 15.0 0.1 0.049 13.2 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EDO18444.1 - 0.054 13.7 0.7 0.15 12.2 0.0 2.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EDO18444.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EDO18444.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Aminotran_1_2 PF00155.16 EDO18445.1 - 5.1e-18 65.1 0.0 7.1e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EDO18445.1 - 0.0006 18.4 0.0 0.00072 18.2 0.0 1.3 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase UPF0160 PF03690.8 EDO18446.1 - 6.4e-125 416.7 0.0 7.2e-125 416.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Sec34 PF04136.10 EDO18448.1 - 1.1e-21 77.2 6.6 1.1e-21 77.2 4.5 3.3 4 0 0 4 4 4 1 Sec34-like family Occludin_ELL PF07303.8 EDO18448.1 - 0.018 15.7 1.8 0.11 13.2 0.8 2.8 1 1 0 1 1 1 0 Occludin homology domain CK2S PF15011.1 EDO18448.1 - 0.08 12.7 0.2 2.2 8.0 0.1 3.0 2 0 0 2 2 2 0 Casein Kinase 2 substrate DDE_1 PF03184.14 EDO18449.1 - 1e-67 227.4 1.7 2.1e-67 226.4 1.2 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO18449.1 - 4.3e-13 48.8 0.4 1.3e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain FAM195 PF14799.1 EDO18449.1 - 0.064 13.1 2.5 0.19 11.6 0.1 2.6 2 0 0 2 2 2 0 FAM195 family Stn1 PF10451.4 EDO18450.1 - 8.6e-98 326.2 1.9 1.3e-97 325.7 1.3 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Stn1_C PF12659.2 EDO18450.1 - 7.4e-38 129.2 4.4 1.2e-37 128.5 3.0 1.3 1 0 0 1 1 1 1 Telomere capping C-terminal wHTH DUF2183 PF09949.4 EDO18450.1 - 0.016 15.1 1.2 0.054 13.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) Methyltransf_8 PF05148.10 EDO18451.1 - 3.5e-65 219.7 2.4 1.2e-62 211.4 0.1 2.8 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EDO18451.1 - 4.4e-08 33.5 0.1 1.5e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO18451.1 - 2.8e-05 23.7 0.3 0.00013 21.5 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO18451.1 - 0.0029 17.9 0.3 0.0091 16.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EDO18451.1 - 0.0077 15.9 0.2 0.021 14.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EDO18451.1 - 0.03 13.7 0.0 0.61 9.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase small domain NAF PF03822.9 EDO18451.1 - 0.62 9.8 3.1 0.67 9.6 0.4 2.3 2 0 0 2 2 2 0 NAF domain AF1Q PF15017.1 EDO18451.1 - 5.3 7.0 8.8 0.15 11.9 1.2 2.0 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Slu7 PF11708.3 EDO18452.1 - 1.5e-45 155.8 8.3 1.5e-45 155.8 5.8 1.8 2 1 1 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor PQ-loop PF04193.9 EDO18453.1 - 1.4e-20 72.6 9.5 3e-17 61.8 2.3 2.7 2 0 0 2 2 2 2 PQ loop repeat ABC_tran PF00005.22 EDO18454.1 - 2.8e-34 118.3 0.0 1.8e-16 60.7 0.0 2.5 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 EDO18454.1 - 3.5e-14 52.0 4.9 8.8e-14 50.8 3.4 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EDO18454.1 - 9.2e-14 52.0 9.8 0.0042 17.0 0.0 4.3 2 2 2 4 4 4 4 AAA domain AAA_15 PF13175.1 EDO18454.1 - 1.8e-09 37.1 0.7 0.17 10.8 0.0 4.2 3 1 1 4 4 4 3 AAA ATPase domain SMC_N PF02463.14 EDO18454.1 - 9.7e-08 31.4 3.2 0.02 14.1 0.2 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 EDO18454.1 - 2.9e-07 29.7 3.5 2.9e-07 29.7 2.4 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain AAA PF00004.24 EDO18454.1 - 6.6e-06 26.3 0.0 0.027 14.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EDO18454.1 - 9.2e-06 24.9 2.2 0.063 12.4 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EDO18454.1 - 1.1e-05 25.4 0.0 0.0024 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EDO18454.1 - 2.3e-05 23.7 0.6 0.13 11.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EDO18454.1 - 4.2e-05 23.6 0.0 0.042 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 EDO18454.1 - 0.00012 21.8 12.3 0.00038 20.2 2.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 EDO18454.1 - 0.00016 22.0 6.1 0.00052 20.3 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_17 PF13207.1 EDO18454.1 - 0.00018 22.3 0.4 0.9 10.3 0.0 2.8 2 2 0 2 2 2 2 AAA domain Fer4_21 PF14697.1 EDO18454.1 - 0.00026 20.7 11.9 0.0006 19.6 8.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Miro PF08477.8 EDO18454.1 - 0.00054 20.4 0.1 1.8 9.0 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein AAA_25 PF13481.1 EDO18454.1 - 0.00065 19.1 0.0 0.42 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EDO18454.1 - 0.0012 17.7 0.0 0.31 9.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_18 PF13238.1 EDO18454.1 - 0.0017 18.6 0.1 2.1 8.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain Fer4_9 PF13187.1 EDO18454.1 - 0.0024 18.1 1.9 0.0024 18.1 1.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EDO18454.1 - 0.0026 17.5 2.4 0.0026 17.5 1.7 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain RNA_helicase PF00910.17 EDO18454.1 - 0.0039 17.3 0.0 1.5 9.0 0.0 2.9 3 0 0 3 3 2 1 RNA helicase NACHT PF05729.7 EDO18454.1 - 0.0043 16.7 1.6 0.41 10.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 EDO18454.1 - 0.0043 17.0 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.1 EDO18454.1 - 0.0053 16.5 1.3 0.0053 16.5 0.9 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain MobB PF03205.9 EDO18454.1 - 0.0057 16.3 1.1 0.95 9.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_3 PF12798.2 EDO18454.1 - 0.0058 17.1 4.2 0.0058 17.1 2.9 2.5 2 0 0 2 2 1 1 4Fe-4S binding domain Fer4_16 PF13484.1 EDO18454.1 - 0.0063 17.2 0.1 0.0063 17.2 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain VirE PF05272.6 EDO18454.1 - 0.007 15.8 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 1 Virulence-associated protein E Rad17 PF03215.10 EDO18454.1 - 0.01 14.5 0.0 1 7.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 EDO18454.1 - 0.011 15.3 0.1 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDO18454.1 - 0.011 15.5 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EDO18454.1 - 0.012 15.5 0.1 14 5.6 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EDO18454.1 - 0.015 14.9 1.1 0.15 11.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EDO18454.1 - 0.018 14.6 0.1 0.34 10.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 EDO18454.1 - 0.019 14.4 3.3 0.58 9.5 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EDO18454.1 - 0.037 14.3 4.6 0.16 12.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EDO18454.1 - 0.039 13.8 0.1 14 5.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 EDO18454.1 - 0.042 14.2 2.2 0.042 14.2 1.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.1 EDO18454.1 - 0.15 12.1 8.0 0.13 12.3 0.8 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain PduV-EutP PF10662.4 EDO18454.1 - 0.19 11.2 1.3 0.57 9.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EDO18454.1 - 0.27 10.7 1.8 2 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 EDO18454.1 - 0.37 9.1 1.1 0.92 7.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain RRM_1 PF00076.17 EDO18455.1 - 8.9e-84 275.1 11.9 4.5e-21 74.2 0.6 4.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO18455.1 - 5.8e-56 186.3 0.5 9.9e-15 54.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO18455.1 - 2.2e-43 145.8 0.2 1.9e-10 40.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EDO18455.1 - 1.5e-21 75.7 1.8 2.9e-21 74.9 0.1 2.4 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EDO18455.1 - 7.7e-06 25.5 0.4 0.29 10.9 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EDO18455.1 - 0.022 14.9 0.1 4.7 7.5 0.0 2.7 2 0 0 2 2 2 0 Cobalamin biosynthesis central region OB_RNB PF08206.6 EDO18455.1 - 0.036 13.5 3.4 8.8 5.9 0.1 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain YflT PF11181.3 EDO18455.1 - 0.13 12.4 6.5 2.2 8.4 0.8 3.5 2 1 1 3 3 3 0 Heat induced stress protein YflT BBE PF08031.7 EDO18455.1 - 0.13 12.2 0.3 15 5.5 0.1 2.7 2 0 0 2 2 2 0 Berberine and berberine like DUF793 PF05633.6 EDO18457.1 - 1.5 7.5 5.0 2.3 6.8 2.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF793) Zip PF02535.17 EDO18457.1 - 5.1 6.0 14.6 8.4 5.2 10.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter zf-H2C2_2 PF13465.1 EDO18458.1 - 3.6e-07 30.1 6.7 3.6e-07 30.1 4.7 2.7 2 0 0 2 2 2 1 Zinc-finger double domain JmjC PF02373.17 EDO18458.1 - 5e-07 29.9 0.4 4.2e-06 26.9 0.0 2.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C2H2 PF00096.21 EDO18458.1 - 6.1e-07 29.4 16.7 0.00091 19.4 2.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO18458.1 - 1.2e-06 28.4 12.9 0.0012 19.0 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDO18458.1 - 0.0013 18.5 10.0 0.0093 15.8 2.8 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger HypA PF01155.14 EDO18458.1 - 0.064 12.9 0.4 0.13 11.9 0.3 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-C4_ClpX PF06689.8 EDO18458.1 - 0.13 11.7 0.5 0.35 10.4 0.1 1.8 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-C2H2_jaz PF12171.3 EDO18458.1 - 0.18 11.9 11.5 0.42 10.8 3.6 2.6 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF1610 PF07754.6 EDO18458.1 - 0.74 9.9 3.1 3.9 7.6 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Zn-ribbon_8 PF09723.5 EDO18458.1 - 1.2 9.1 6.2 5.8 6.9 4.3 2.1 1 1 0 1 1 1 0 Zinc ribbon domain zf-met PF12874.2 EDO18458.1 - 5.3 7.3 8.8 24 5.3 0.5 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ADK PF00406.17 EDO18459.1 - 2.7e-41 140.9 0.0 3.3e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EDO18459.1 - 1.6e-13 50.0 0.1 2.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EDO18459.1 - 9.4e-05 22.7 0.0 0.00021 21.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDO18459.1 - 0.00086 19.1 0.0 0.0035 17.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EDO18459.1 - 0.011 14.9 0.1 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EDO18459.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EDO18459.1 - 0.14 12.9 0.0 0.38 11.5 0.0 1.8 1 1 1 2 2 2 0 AAA domain DUF1227 PF06777.6 EDO18460.1 - 1.2e-58 196.9 1.4 2.9e-58 195.7 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EDO18460.1 - 1.9e-52 177.1 3.7 3.3e-52 176.4 2.6 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EDO18460.1 - 1.4e-45 155.2 0.0 7.3e-45 152.9 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 EDO18460.1 - 0.0016 17.9 0.2 0.72 9.3 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase SNF2_N PF00176.18 EDO18460.1 - 0.0083 14.9 1.0 0.95 8.2 0.0 2.9 2 1 1 3 3 3 1 SNF2 family N-terminal domain ResIII PF04851.10 EDO18460.1 - 0.063 13.1 0.2 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Methyltransf_31 PF13847.1 EDO18461.1 - 1.8e-13 50.3 0.1 3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO18461.1 - 6.9e-12 45.6 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO18461.1 - 1.3e-10 41.6 0.2 1.1e-09 38.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO18461.1 - 2.4e-09 37.0 0.0 3.5e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO18461.1 - 7.7e-08 32.6 0.0 1.8e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO18461.1 - 6.4e-07 29.9 0.0 1.1e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EDO18461.1 - 5.1e-05 22.4 0.1 9.2e-05 21.6 0.1 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EDO18461.1 - 0.00011 21.4 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EDO18461.1 - 0.0028 16.7 0.0 0.0056 15.7 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase NodS PF05401.6 EDO18461.1 - 0.0077 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 EDO18461.1 - 0.009 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EDO18461.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EDO18461.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EDO18461.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Rsm22 PF09243.5 EDO18461.1 - 0.024 13.6 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_9 PF08003.6 EDO18461.1 - 0.06 12.0 0.1 0.51 8.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) FtsJ PF01728.14 EDO18461.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Rrn6 PF10214.4 EDO18462.1 - 2e-195 651.2 36.4 2.7e-195 650.7 25.2 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Formyl_trans_N PF00551.14 EDO18463.1 - 8.2e-30 103.6 0.0 1.2e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EDO18463.1 - 0.0013 18.7 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain DUF3635 PF12330.3 EDO18464.1 - 3.9e-15 55.7 1.0 1e-14 54.3 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) Pkinase_Tyr PF07714.12 EDO18464.1 - 0.014 14.4 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase ATE_C PF04377.10 EDO18465.1 - 2.9e-40 137.2 0.9 6e-40 136.2 0.6 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EDO18465.1 - 1.5e-23 82.4 2.6 9.5e-23 79.8 1.5 2.3 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus WD40 PF00400.27 EDO18467.1 - 2.7e-44 147.4 15.3 5e-11 42.0 0.0 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 EDO18467.1 - 1.1e-10 40.7 2.8 1.5e-10 40.3 0.1 2.4 2 0 0 2 2 2 1 HIRA B motif Hira PF07569.6 EDO18467.1 - 1.8e-05 24.0 0.0 4.3e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split PD40 PF07676.7 EDO18467.1 - 0.00042 19.9 0.3 18 5.1 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EDO18467.1 - 0.0086 15.2 0.0 0.031 13.3 0.0 2.0 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Reg_prop PF07494.6 EDO18467.1 - 0.17 12.0 1.4 7.2 7.0 0.0 4.0 4 0 0 4 4 4 0 Two component regulator propeller TBPIP PF07106.8 EDO18468.1 - 1.2e-10 41.1 9.4 1.5e-10 40.9 6.5 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MGAT2 PF05060.9 EDO18468.1 - 0.013 14.4 1.1 0.017 14.0 0.8 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Bacillus_HBL PF05791.6 EDO18468.1 - 0.033 13.5 6.1 0.065 12.5 3.8 1.7 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) IncA PF04156.9 EDO18468.1 - 0.23 11.0 3.4 0.26 10.8 2.4 1.1 1 0 0 1 1 1 0 IncA protein Syntaxin_2 PF14523.1 EDO18468.1 - 0.3 11.1 7.6 0.38 10.7 2.0 2.2 1 1 1 2 2 2 0 Syntaxin-like protein TMPIT PF07851.8 EDO18468.1 - 0.52 9.3 4.6 0.65 9.0 3.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein Baculo_PEP_C PF04513.7 EDO18468.1 - 0.57 9.9 5.5 0.71 9.6 1.7 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IQ-like PF15157.1 EDO18468.1 - 1.8 8.8 4.9 7.4 6.8 0.1 2.2 1 1 1 2 2 2 0 IQ-like DUF3432 PF11914.3 EDO18469.1 - 0.00076 19.4 29.3 0.079 12.9 20.1 3.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3432) SNARE PF05739.14 EDO18469.1 - 0.0025 17.4 3.3 0.0025 17.4 2.3 3.4 3 0 0 3 3 3 2 SNARE domain 4F5 PF04419.9 EDO18470.1 - 1.6e-09 38.3 12.4 1.6e-09 38.3 8.6 2.2 2 0 0 2 2 2 1 4F5 protein family DUF1675 PF07897.6 EDO18470.1 - 1.3 8.7 7.3 1.3 8.7 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) CRF PF00473.12 EDO18470.1 - 4 7.6 7.3 0.28 11.3 1.6 1.7 2 0 0 2 2 2 0 Corticotropin-releasing factor family DDRGK PF09756.4 EDO18470.1 - 8.2 5.7 13.9 8.9 5.6 9.6 1.0 1 0 0 1 1 1 0 DDRGK domain WD40 PF00400.27 EDO18471.1 - 9.5e-30 101.3 4.2 2.4e-09 36.6 0.2 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat SGL PF08450.7 EDO18471.1 - 0.002 17.5 0.1 0.0069 15.7 0.0 1.9 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region MUG113 PF13455.1 EDO18472.1 - 2.6e-09 37.4 0.0 0.00044 20.6 0.0 2.2 2 0 0 2 2 2 2 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EDO18472.1 - 3.2e-09 37.1 0.4 2.5e-07 30.9 0.3 2.3 1 1 0 1 1 1 1 T5orf172 domain Flu_PB1 PF00602.12 EDO18472.1 - 0.063 11.0 1.9 0.075 10.7 1.3 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 ADH_zinc_N_2 PF13602.1 EDO18475.1 - 1.1e-14 55.4 0.0 2.4e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO18475.1 - 6.9e-07 29.0 0.1 1.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO18475.1 - 4.2e-05 23.0 0.0 0.00071 19.1 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 EDO18475.1 - 0.042 13.6 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2855 PF11017.3 EDO18475.1 - 0.049 12.7 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) DUF2418 PF10332.4 EDO18476.1 - 4.2e-31 107.1 1.5 4.2e-31 107.1 1.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) UBX PF00789.15 EDO18478.1 - 3.6e-17 62.2 0.0 6.7e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain DUF4389 PF14333.1 EDO18478.1 - 0.075 12.7 0.9 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) PMT PF02366.13 EDO18479.1 - 2.3e-77 259.6 19.4 2.3e-77 259.6 13.4 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDO18479.1 - 3.3e-49 167.0 0.3 7.4e-49 165.8 0.2 1.6 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 EDO18479.1 - 2.2e-05 24.4 18.8 2.2e-05 24.4 13.0 3.6 3 2 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase RTX_C PF08339.5 EDO18479.1 - 0.0032 17.1 16.5 1.1 8.9 0.9 3.7 3 0 0 3 3 3 3 RTX C-terminal domain TOM_sub5 PF15178.1 EDO18479.1 - 0.016 14.8 0.0 23 4.7 0.0 4.3 4 0 0 4 4 4 0 Mitochondrial import receptor subunit TOM5 homolog HTH_21 PF13276.1 EDO18479.1 - 0.072 13.1 0.1 54 3.8 0.0 4.2 5 0 0 5 5 5 0 HTH-like domain Acp26Ab PF05777.7 EDO18479.1 - 0.14 12.5 2.9 39 4.7 0.0 3.8 3 0 0 3 3 3 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) PCI PF01399.22 EDO18480.1 - 2.9e-17 62.8 2.3 5.7e-17 61.9 0.0 2.7 3 1 0 3 3 3 1 PCI domain TPR_16 PF13432.1 EDO18480.1 - 2.7e-05 24.6 0.0 0.38 11.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EDO18480.1 - 0.0011 18.0 1.2 0.0011 18.0 0.8 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat DDRGK PF09756.4 EDO18480.1 - 0.034 13.5 2.5 0.034 13.5 0.0 2.2 2 1 1 3 3 3 0 DDRGK domain YflT PF11181.3 EDO18480.1 - 0.043 13.9 0.4 0.14 12.3 0.3 1.9 1 0 0 1 1 1 0 Heat induced stress protein YflT Apc3 PF12895.2 EDO18480.1 - 0.14 12.3 18.4 0.076 13.1 2.2 4.1 5 1 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EDO18480.1 - 0.15 12.0 9.7 0.3 11.0 1.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PNK3P PF08645.6 EDO18481.1 - 1.6e-44 151.1 0.2 1.8e-44 150.9 0.2 1.0 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Fe_dep_repress PF01325.14 EDO18481.1 - 0.11 12.4 0.2 7.8 6.5 0.1 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain zf-met PF12874.2 EDO18482.1 - 4.9e-07 29.7 2.2 9.7e-07 28.7 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EDO18482.1 - 2.9e-05 24.0 3.0 8.2e-05 22.6 2.1 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EDO18482.1 - 0.033 14.3 0.3 0.055 13.5 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EDO18482.1 - 0.19 11.7 1.1 0.49 10.3 0.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO18482.1 - 0.35 11.3 2.0 0.73 10.2 1.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type SlyX PF04102.7 EDO18483.1 - 0.011 16.0 6.0 0.011 16.0 4.2 4.4 2 1 2 4 4 4 0 SlyX DUF848 PF05852.6 EDO18483.1 - 0.016 15.0 12.2 0.016 15.0 8.5 3.0 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) FlxA PF14282.1 EDO18483.1 - 0.02 14.8 17.0 0.02 14.8 11.8 3.9 3 1 0 3 3 3 0 FlxA-like protein Reo_sigmaC PF04582.7 EDO18483.1 - 0.037 13.2 4.2 0.053 12.6 2.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Pox_A_type_inc PF04508.7 EDO18483.1 - 1.3 9.0 13.8 1.2 9.0 0.3 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Daxx PF03344.10 EDO18483.1 - 2.8 6.2 43.7 3.7 5.9 30.3 1.1 1 0 0 1 1 1 0 Daxx Family ArsA_ATPase PF02374.10 EDO18484.1 - 1.9e-116 388.4 0.0 2.2e-116 388.1 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EDO18484.1 - 2.4e-12 46.6 0.5 4.5e-12 45.7 0.3 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EDO18484.1 - 6.4e-05 22.9 0.0 0.00015 21.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EDO18484.1 - 0.0013 18.0 0.0 0.0027 16.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EDO18484.1 - 0.023 14.1 0.0 0.53 9.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EDO18484.1 - 0.025 13.9 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EDO18484.1 - 0.087 12.4 0.1 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EDO18484.1 - 0.098 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Cpn60_TCP1 PF00118.19 EDO18485.1 - 8.8e-138 459.9 4.9 1e-137 459.7 3.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 EDO18485.1 - 0.077 13.0 0.0 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor PUF PF00806.14 EDO18486.1 - 4.2e-31 104.6 6.5 3.2e-05 23.1 0.0 8.3 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat DUF3294 PF07957.6 EDO18487.1 - 3.5e-90 301.2 4.0 3.9e-90 301.1 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) FlaC_arch PF05377.6 EDO18487.1 - 0.15 11.9 1.2 0.89 9.4 0.6 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BRE1 PF08647.6 EDO18487.1 - 0.2 11.6 5.6 0.5 10.3 3.8 1.7 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase LTV PF04180.9 EDO18488.1 - 1.9e-112 376.8 47.7 5.5e-112 375.3 33.1 1.6 1 1 0 1 1 1 1 Low temperature viability protein RNA_pol_Rbc25 PF08292.7 EDO18489.1 - 2e-46 157.1 0.2 2.9e-46 156.6 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EDO18489.1 - 1.2e-20 73.4 0.0 1.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EDO18489.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.7 1 1 0 1 1 1 0 S1 RNA binding domain AAA PF00004.24 EDO18490.1 - 2.4e-40 137.7 0.0 4.8e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO18490.1 - 7.6e-06 26.0 0.0 0.00098 19.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EDO18490.1 - 2.5e-05 24.0 0.0 0.00012 21.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO18490.1 - 0.00012 22.0 0.0 0.00036 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EDO18490.1 - 0.0003 20.7 0.0 0.00068 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EDO18490.1 - 0.0011 18.0 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EDO18490.1 - 0.0011 19.7 0.1 0.0039 18.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EDO18490.1 - 0.0052 15.8 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EDO18490.1 - 0.0067 16.1 0.2 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EDO18490.1 - 0.0098 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDO18490.1 - 0.013 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EDO18490.1 - 0.016 15.4 0.1 0.062 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EDO18490.1 - 0.02 14.7 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EDO18490.1 - 0.024 14.3 0.0 4.7 6.8 0.0 2.5 1 1 1 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 EDO18490.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDO18490.1 - 0.03 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EDO18490.1 - 0.032 14.3 0.0 0.072 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EDO18490.1 - 0.035 13.7 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EDO18490.1 - 0.038 12.7 0.0 0.079 11.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EDO18490.1 - 0.043 13.8 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 EDO18490.1 - 0.048 12.8 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EDO18490.1 - 0.083 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Aa_trans PF01490.13 EDO18491.1 - 5.8e-93 311.5 35.5 7e-93 311.3 24.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EDO18491.1 - 0.00025 20.0 12.0 0.00025 20.0 8.3 2.6 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family DBR1 PF05011.8 EDO18492.1 - 1.8e-10 40.8 0.2 3.4e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EDO18492.1 - 2.1e-08 33.8 11.1 2.1e-08 33.8 4.9 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase DPM2 PF07297.7 EDO18494.1 - 2.4e-09 37.3 6.9 2.7e-09 37.1 4.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EDO18494.1 - 0.003 17.1 9.5 0.0033 17.0 6.6 1.0 1 0 0 1 1 1 1 PIG-P Oxidored_q4 PF00507.14 EDO18494.1 - 7.2 6.4 10.6 10 6.0 7.3 1.3 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 SRPRB PF09439.5 EDO18495.1 - 2.8e-62 209.1 1.9 3.7e-62 208.7 1.3 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EDO18495.1 - 1.5e-09 37.3 0.1 2.3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EDO18495.1 - 4.6e-07 29.8 0.1 7.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO18495.1 - 4.5e-05 22.7 0.1 0.00012 21.3 0.0 1.8 1 1 1 2 2 2 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 EDO18495.1 - 0.00056 19.6 0.1 0.0074 16.0 0.1 2.2 1 1 0 1 1 1 1 Archaeal ATPase Miro PF08477.8 EDO18495.1 - 0.00082 19.8 0.1 0.0017 18.8 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein ATP_bind_1 PF03029.12 EDO18495.1 - 0.05 13.1 1.5 0.14 11.6 0.6 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 EDO18495.1 - 0.77 10.0 9.4 1.7 8.9 6.5 1.6 1 1 0 1 1 1 0 AAA domain Rsm22 PF09243.5 EDO18496.1 - 7.8e-26 90.7 0.1 4.8e-10 38.9 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Ribosomal_S27e PF01667.12 EDO18497.1 - 2e-30 104.0 2.7 2.8e-30 103.6 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EDO18497.1 - 7e-05 22.6 0.6 8.6e-05 22.3 0.4 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 EDO18497.1 - 0.05 12.9 3.8 0.072 12.4 2.6 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 EDO18497.1 - 0.12 11.9 1.3 6.1 6.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EDO18497.1 - 0.13 11.9 1.3 6.2 6.6 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Peptidase_M16_C PF05193.16 EDO18498.1 - 5.7e-44 149.9 0.0 1.1e-42 145.8 0.0 2.3 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EDO18498.1 - 7.1e-42 142.6 0.0 4.4e-41 140.1 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) GHMP_kinases_N PF00288.21 EDO18499.1 - 4.1e-13 49.2 0.0 9.4e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EDO18499.1 - 0.00014 22.0 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal ATP-synt_C PF00137.16 EDO18500.1 - 6e-31 106.1 23.6 1e-18 66.9 6.8 2.2 2 0 0 2 2 2 2 ATP synthase subunit C BP28CT PF08146.7 EDO18501.1 - 1.8e-41 141.4 4.0 1.8e-41 141.4 2.8 3.2 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EDO18501.1 - 1.2e-21 76.9 3.1 1.2e-21 76.9 2.1 3.7 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EDO18501.1 - 4.6e-05 23.6 0.1 2.7 8.3 0.0 5.2 6 0 0 6 6 6 2 HEAT repeats HEAT PF02985.17 EDO18501.1 - 0.00044 20.1 3.1 0.79 9.9 0.0 5.3 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EDO18501.1 - 0.29 11.6 0.8 26 5.4 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat UNC-50 PF05216.8 EDO18502.1 - 7.8e-92 306.6 22.6 8.9e-92 306.4 15.6 1.0 1 0 0 1 1 1 1 UNC-50 family Mito_carr PF00153.22 EDO18503.1 - 3.4e-60 199.7 3.4 1.5e-20 72.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PAP2 PF01569.16 EDO18504.1 - 4.2e-15 55.5 1.1 4.2e-15 55.5 0.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily Fer4_5 PF12801.2 EDO18504.1 - 1.4 8.7 6.4 0.4 10.5 1.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain tRNA_U5-meth_tr PF05958.6 EDO18505.1 - 3.9e-22 78.4 0.1 4.2e-21 75.0 0.1 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EDO18505.1 - 7.3e-12 45.1 0.0 1.9e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.15 EDO18505.1 - 1.4e-11 44.0 0.1 2.6e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_18 PF12847.2 EDO18505.1 - 1.7e-06 28.5 0.0 3.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDO18505.1 - 9e-06 25.0 0.0 2.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EDO18505.1 - 2.5e-05 23.8 0.1 6.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 EDO18505.1 - 3e-05 23.4 0.0 7.4e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EDO18505.1 - 3.5e-05 23.8 0.0 5.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO18505.1 - 0.0001 21.4 0.1 0.0025 16.9 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EDO18505.1 - 0.00019 20.8 0.0 0.00039 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EDO18505.1 - 0.00067 18.7 0.2 0.0024 16.9 0.0 2.0 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EDO18505.1 - 0.0024 18.2 0.0 0.0093 16.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EDO18505.1 - 0.0048 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EDO18505.1 - 0.024 14.2 0.0 0.061 12.9 0.0 1.7 1 0 0 1 1 1 0 Met-10+ like-protein Pox_D2 PF04701.8 EDO18505.1 - 0.029 14.3 0.2 0.099 12.6 0.1 1.9 1 0 0 1 1 1 0 Pox virus D2 protein UPF0020 PF01170.13 EDO18505.1 - 0.03 13.9 0.0 0.46 10.0 0.0 2.2 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Ribosomal_S21e PF01249.13 EDO18506.1 - 6.5e-34 115.7 0.0 7.2e-34 115.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Glyco_transf_8 PF01501.15 EDO18507.1 - 2.4e-32 112.2 0.8 4.1e-32 111.4 0.6 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_15 PF01793.11 EDO18508.1 - 1.2e-128 428.7 16.0 1.5e-128 428.4 11.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Pkinase PF00069.20 EDO18509.1 - 1.6e-52 178.2 2.6 4.1e-52 176.8 0.1 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18509.1 - 4.7e-20 71.7 0.0 1.1e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO18509.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EDO18509.1 - 0.0066 15.8 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EDO18509.1 - 0.16 11.2 2.0 0.42 9.9 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Tim17 PF02466.14 EDO18510.1 - 2.4e-32 111.6 5.3 2.9e-32 111.4 3.7 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF87 PF01935.12 EDO18511.1 - 0.04 13.7 1.8 0.1 12.3 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 FBP PF07299.6 EDO18512.1 - 1.9 7.7 10.1 0.23 10.7 0.1 3.0 2 1 1 3 3 3 0 Fibronectin-binding protein (FBP) RNA_polI_A34 PF08208.6 EDO18513.1 - 8.5e-42 143.0 18.5 1.2e-41 142.5 12.8 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Med19 PF10278.4 EDO18513.1 - 1 8.9 17.0 1.5 8.5 10.2 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Las1 PF04031.8 EDO18514.1 - 2.5e-52 176.6 1.1 5.1e-52 175.6 0.1 2.0 2 1 0 2 2 2 1 Las1-like Sdh5 PF03937.11 EDO18514.1 - 0.0038 16.8 0.8 0.7 9.6 0.0 2.8 2 0 0 2 2 2 2 Flavinator of succinate dehydrogenase Zn_clus PF00172.13 EDO18515.1 - 4.6e-08 32.8 10.5 9.7e-08 31.8 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EDO18515.1 - 0.00061 18.7 0.2 0.0013 17.6 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain NAD_binding_5 PF07994.7 EDO18516.1 - 5.8e-114 380.5 0.2 6.6e-114 380.3 0.2 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EDO18516.1 - 4.1e-42 142.5 0.6 8e-42 141.6 0.4 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Vps35 PF03635.12 EDO18517.1 - 2.2e-162 541.9 39.5 3.3e-162 541.4 27.4 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 6PF2K PF01591.13 EDO18518.1 - 6.2e-83 277.2 2.1 8.6e-83 276.7 1.5 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EDO18518.1 - 9.5e-32 110.2 0.0 2.2e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EDO18518.1 - 1.4e-07 31.4 0.0 3.4e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EDO18518.1 - 3.5e-05 24.6 1.1 0.0009 20.0 0.0 2.9 2 1 1 3 3 3 1 AAA domain DUF2704 PF10866.3 EDO18518.1 - 0.037 13.4 0.1 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2704) zf-RING_2 PF13639.1 EDO18519.1 - 0.003 17.3 9.8 0.0058 16.4 6.8 1.5 1 0 0 1 1 1 1 Ring finger domain PIR PF00399.14 EDO18520.1 - 2.7e-14 51.8 13.4 1.5e-08 33.6 3.3 3.3 2 0 0 2 2 2 2 Yeast PIR protein repeat LEA_6 PF10714.4 EDO18520.1 - 6.7 6.6 8.7 4.3 7.2 0.7 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 PIR PF00399.14 EDO18521.1 - 2.8e-78 254.8 142.9 3.3e-08 32.5 4.1 10.7 10 0 0 10 10 10 10 Yeast PIR protein repeat HCV_NS5a_1a PF08300.8 EDO18521.1 - 0.00011 22.0 7.6 27 4.7 0.0 5.2 1 1 4 5 5 5 4 Hepatitis C virus non-structural 5a zinc finger domain DUF2807 PF10988.3 EDO18521.1 - 0.15 11.6 29.9 0.2 11.1 8.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2807) SCP2 PF02036.12 EDO18521.1 - 6.4 7.1 8.4 13 6.1 0.7 3.2 1 1 2 3 3 3 0 SCP-2 sterol transfer family DnaJ PF00226.26 EDO18523.1 - 2.4e-18 65.6 0.5 2.4e-18 65.6 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain MFS_1 PF07690.11 EDO18524.1 - 1.7e-22 79.6 14.6 1.7e-22 79.6 10.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF843 PF05814.6 EDO18524.1 - 0.013 15.2 1.3 0.12 12.2 0.0 3.2 2 1 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Adeno_E3_14_5 PF04834.7 EDO18524.1 - 0.13 12.6 2.7 2.7 8.4 0.8 3.3 1 1 1 2 2 2 0 Early E3 14.5 kDa protein Pkinase PF00069.20 EDO18525.1 - 3.9e-49 167.1 0.0 6.3e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18525.1 - 5.2e-19 68.3 0.0 1.1e-18 67.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EDO18525.1 - 0.021 13.9 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EDO18525.1 - 0.029 13.3 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EDO18525.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EDO18526.1 - 9.3e-41 139.6 0.1 3.6e-28 98.4 0.3 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18526.1 - 6.6e-22 77.8 0.3 3.4e-18 65.6 0.3 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EDO18526.1 - 0.014 14.3 0.0 1.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EDO18526.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ebp2 PF05890.7 EDO18527.1 - 2.2e-87 292.7 27.1 2.2e-87 292.7 18.8 3.0 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 GTP_EFTU PF00009.22 EDO18528.1 - 4.7e-33 114.1 0.0 7.4e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EDO18528.1 - 9.8e-16 57.4 0.1 3.7e-15 55.5 0.0 2.1 3 0 0 3 3 2 1 Elongation factor G C-terminus EFG_IV PF03764.13 EDO18528.1 - 7.2e-13 48.1 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EDO18528.1 - 1.2e-07 31.4 0.0 2.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EDO18528.1 - 3.2e-05 23.9 0.0 8.7e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 EDO18528.1 - 0.00084 19.8 0.2 0.0036 17.7 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EDO18528.1 - 0.0028 17.5 0.3 0.006 16.5 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EDO18528.1 - 0.0077 15.4 0.2 0.12 11.5 0.1 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EDO18528.1 - 0.0092 15.3 0.3 0.23 10.8 0.2 2.5 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 EDO18528.1 - 0.08 12.7 0.9 6.4 6.5 0.1 2.5 1 1 1 2 2 2 0 Dynamin family AAA_29 PF13555.1 EDO18528.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EDO18528.1 - 0.23 10.8 0.0 0.45 9.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zip PF02535.17 EDO18529.1 - 5.4e-28 97.9 4.3 5.4e-28 97.9 3.0 2.0 1 1 1 2 2 2 1 ZIP Zinc transporter DUF1761 PF08570.5 EDO18529.1 - 0.0028 17.6 0.4 0.022 14.8 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1761) SRI PF08236.6 EDO18530.1 - 1.2e-28 98.8 7.3 1.2e-28 98.8 5.0 2.3 2 1 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 EDO18530.1 - 6.2e-24 85.1 0.8 6.2e-24 85.1 0.5 3.9 3 2 0 3 3 3 1 SET domain Toxin_67 PF15545.1 EDO18530.1 - 0.016 15.1 0.1 0.063 13.1 0.0 2.1 1 0 0 1 1 1 0 Putative toxin 67 WW PF00397.21 EDO18530.1 - 0.076 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 WW domain Mem_trans PF03547.13 EDO18531.1 - 0.01 14.1 0.5 0.013 13.8 0.3 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF2401 PF10287.4 EDO18532.1 - 2.8e-89 298.6 2.3 3.8e-89 298.2 1.6 1.1 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EDO18532.1 - 3.2e-25 88.0 0.2 8e-25 86.7 0.1 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) EndoU_bacteria PF14436.1 EDO18532.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial EndoU nuclease STE3 PF02076.10 EDO18533.1 - 1.7e-98 329.1 18.8 2.1e-98 328.9 13.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor KRE9 PF05390.6 EDO18534.1 - 4.4e-44 149.2 8.5 1.2e-43 147.8 5.9 1.8 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 EDO18534.1 - 5e-08 33.3 1.5 5e-08 33.3 1.0 2.9 2 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Arylsulfotrans PF05935.6 EDO18534.1 - 0.0043 15.6 0.8 0.006 15.1 0.6 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) DUF218 PF02698.12 EDO18534.1 - 0.12 11.8 0.2 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 DUF218 domain CBM_19 PF03427.8 EDO18534.1 - 3.2 7.5 6.8 0.21 11.4 0.8 2.0 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) SWIRM PF04433.12 EDO18535.1 - 5.2e-33 113.0 0.1 1.4e-32 111.6 0.1 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EDO18535.1 - 3.5e-09 36.5 0.1 7.2e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO18535.1 - 8.2e-07 29.0 0.0 3.5e-06 27.0 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3781 PF12636.2 EDO18535.1 - 1.7 8.6 5.8 0.77 9.7 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) ATP12 PF07542.6 EDO18536.1 - 1.2e-31 109.1 0.0 2.8e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein Gon7 PF08738.5 EDO18538.1 - 6.6e-38 128.8 0.7 8.3e-38 128.5 0.5 1.1 1 0 0 1 1 1 1 Gon7 family TPR_MLP1_2 PF07926.7 EDO18538.1 - 0.01 15.5 1.4 0.015 15.0 1.0 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein COG2 PF06148.6 EDO18538.1 - 0.026 14.4 0.2 0.036 13.9 0.2 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 NUC153 PF08159.7 EDO18538.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 NUC153 domain muHD PF10291.4 EDO18539.1 - 6.9e-76 254.8 0.4 1e-75 254.2 0.2 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EDO18540.1 - 0.00035 20.7 0.6 0.00072 19.6 0.4 1.6 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain PAD PF03068.10 EDO18540.1 - 0.0045 15.4 0.4 0.05 12.0 0.1 1.9 1 1 1 2 2 2 1 Protein-arginine deiminase (PAD) FbpA PF05833.6 EDO18540.1 - 0.013 14.0 1.8 0.018 13.6 1.2 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) UBN2 PF14223.1 EDO18540.1 - 0.057 13.2 0.3 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Pkinase PF00069.20 EDO18541.1 - 2.2e-47 161.3 0.0 4.2e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18541.1 - 3.5e-29 101.6 0.0 6.4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO18541.1 - 0.011 14.6 0.0 0.29 10.0 0.0 2.4 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EDO18541.1 - 0.066 12.9 0.0 0.56 9.8 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L39 PF00832.15 EDO18542.1 - 2.1e-23 81.4 11.7 2.4e-23 81.3 8.1 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Gas_vesicle_C PF01304.12 EDO18542.1 - 0.053 13.1 0.4 0.082 12.5 0.3 1.3 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Ribosomal_S8 PF00410.14 EDO18543.1 - 1.7e-26 92.5 0.1 2.3e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.14 EDO18544.1 - 3.9e-26 91.3 0.6 4.5e-26 91.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Myb_DNA-binding PF00249.26 EDO18545.1 - 5.5e-17 61.5 0.0 1.4e-07 31.4 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO18545.1 - 6.2e-07 29.4 0.6 0.034 14.2 0.1 3.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain ELO PF01151.13 EDO18546.1 - 5.8e-63 212.5 27.4 7e-63 212.2 19.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family RNase_PH PF01138.16 EDO18547.1 - 1.5e-22 80.3 0.0 4.3e-22 78.8 0.0 1.8 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EDO18547.1 - 0.033 14.1 0.2 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 PfkB PF00294.19 EDO18548.1 - 2.3e-42 145.1 5.4 9.6e-42 143.1 3.8 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase MoCF_biosynth PF00994.19 EDO18548.1 - 0.0018 17.6 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain Phos_pyr_kin PF08543.7 EDO18548.1 - 0.013 14.7 0.2 0.031 13.4 0.1 1.7 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase UCH PF00443.24 EDO18549.1 - 2.9e-86 288.9 2.2 2.9e-86 288.9 1.6 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO18549.1 - 1e-21 77.6 3.1 2e-12 47.2 0.2 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EDO18549.1 - 3.6e-05 24.0 1.1 0.0002 21.6 0.8 2.5 1 0 0 1 1 1 1 DUSP domain SPX PF03105.14 EDO18550.1 - 2.7e-43 148.7 39.9 4.1e-41 141.5 27.7 2.4 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EDO18550.1 - 1.9e-19 69.9 39.6 2.6e-19 69.4 27.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EDO18550.1 - 1e-14 53.9 40.0 5.5e-14 51.5 13.8 2.2 1 1 1 2 2 2 2 Citrate transporter Aconitase PF00330.15 EDO18551.1 - 2.7e-168 560.2 0.0 9.7e-168 558.4 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EDO18551.1 - 6.8e-42 142.6 0.0 1.2e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 EDO18551.1 - 0.12 10.8 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) RasGEF PF00617.14 EDO18552.1 - 2.2e-47 161.2 6.0 2.2e-47 161.2 4.2 3.0 3 1 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 EDO18552.1 - 6.4e-14 51.9 1.1 6.4e-14 51.9 0.8 3.1 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.23 EDO18552.1 - 0.00076 18.8 0.1 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain CRAL_TRIO_2 PF13716.1 EDO18553.1 - 5.1e-32 110.8 2.5 8.8e-32 110.0 0.9 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EDO18553.1 - 9e-10 38.3 1.2 4.3e-09 36.1 0.1 2.7 2 1 0 2 2 2 1 RhoGAP domain FlxA PF14282.1 EDO18554.1 - 0.01 15.7 0.9 0.019 14.9 0.6 1.4 1 0 0 1 1 1 0 FlxA-like protein TBPIP PF07106.8 EDO18554.1 - 0.1 12.1 2.4 0.14 11.7 1.7 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EDO18554.1 - 0.41 11.0 1.9 0.63 10.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) EAP30 PF04157.11 EDO18555.1 - 0.014 14.5 1.4 0.015 14.4 0.9 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family DUF4041 PF13250.1 EDO18555.1 - 0.021 14.3 0.6 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) MgtE_N PF03448.12 EDO18555.1 - 0.076 13.3 3.0 0.088 13.1 2.1 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain FAA_hydrolase_N PF09298.6 EDO18555.1 - 0.16 12.0 0.5 0.17 11.8 0.4 1.2 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal DUF1840 PF08895.6 EDO18555.1 - 0.36 10.8 2.6 4 7.5 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) AKNA PF12443.3 EDO18555.1 - 0.41 10.6 3.2 0.41 10.6 0.2 1.9 1 1 1 2 2 2 0 AT-hook-containing transcription factor Lectin_N PF03954.9 EDO18555.1 - 0.5 9.7 2.7 2.7 7.3 1.9 1.8 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Mnd1 PF03962.10 EDO18555.1 - 0.54 9.8 6.0 0.56 9.8 4.2 1.0 1 0 0 1 1 1 0 Mnd1 family CR6_interact PF10147.4 EDO18555.1 - 0.97 8.7 6.4 1.2 8.3 4.4 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 bZIP_1 PF00170.16 EDO18555.1 - 1.1 9.2 5.0 16 5.5 0.2 2.2 1 1 1 2 2 2 0 bZIP transcription factor Atg14 PF10186.4 EDO18555.1 - 1.2 7.9 4.3 1.3 7.9 3.0 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4164 PF13747.1 EDO18555.1 - 1.6 8.9 7.1 1.7 8.8 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Spc24 PF08286.6 EDO18555.1 - 5.3 6.7 7.9 7.9 6.2 1.0 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TMA7 PF09072.5 EDO18555.1 - 5.5 7.5 6.3 2.9 8.4 0.6 2.3 1 1 1 2 2 2 0 Translation machinery associated TMA7 PRP21_like_P PF12230.3 EDO18556.1 - 2.8e-58 197.1 16.0 4.6e-58 196.4 11.1 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EDO18556.1 - 2e-14 52.9 2.3 1.5e-08 34.1 0.2 2.7 2 0 0 2 2 2 2 Surp module Sec31 PF11549.3 EDO18557.1 - 1.5e-28 98.1 2.5 3.4e-28 97.0 1.0 2.2 2 0 0 2 2 2 1 Protein transport protein SEC31 WD40 PF00400.27 EDO18557.1 - 6.4e-10 38.5 12.0 0.093 12.6 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 EDO18557.1 - 1.7e-05 24.5 0.1 1.7e-05 24.5 0.0 3.2 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 EDO18557.1 - 0.0088 15.8 3.7 0.015 15.1 0.6 2.7 2 1 1 3 3 3 1 Prp18 domain Pro_isomerase PF00160.16 EDO18558.1 - 2.7e-44 151.0 0.2 5.1e-44 150.2 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EDO18558.1 - 6.9e-06 25.6 0.6 0.014 15.0 0.2 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EDO18558.1 - 0.00016 21.1 2.3 0.00035 20.0 0.0 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO18558.1 - 0.0002 21.0 0.5 0.006 16.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO18558.1 - 0.027 14.9 0.1 0.11 13.0 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDO18558.1 - 0.06 13.1 1.2 0.13 12.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat YqeY PF09424.5 EDO18558.1 - 0.12 12.2 0.2 0.12 12.2 0.2 1.9 2 0 0 2 2 2 0 Yqey-like protein TPR_9 PF13371.1 EDO18558.1 - 0.16 11.8 0.4 0.3 10.9 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.9 EDO18559.1 - 2.1e-131 438.7 3.6 3.8e-131 437.9 2.5 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EDO18559.1 - 7.9e-68 228.9 0.0 1.2e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EDO18559.1 - 2.8e-57 188.6 12.2 4.4e-10 39.0 0.0 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EDO18559.1 - 3.4e-07 28.7 6.8 0.016 13.3 0.2 4.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EDO18559.1 - 0.00013 21.7 0.1 0.95 9.1 0.0 3.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A DEAD PF00270.24 EDO18560.1 - 1.1e-42 145.4 0.1 1.7e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO18560.1 - 1.5e-25 88.8 0.2 3.5e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.27 EDO18561.1 - 1.1e-41 139.2 16.1 3.9e-10 39.2 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat IKI3 PF04762.7 EDO18561.1 - 0.019 12.8 0.3 0.36 8.6 0.0 2.3 2 0 0 2 2 2 0 IKI3 family Sel1 PF08238.7 EDO18562.1 - 8.4e-25 86.6 20.0 7e-07 29.6 0.6 9.3 10 0 0 10 10 9 5 Sel1 repeat TPR_11 PF13414.1 EDO18562.1 - 6.3e-06 25.7 0.5 6.3e-06 25.7 0.3 5.7 4 2 2 6 6 6 1 TPR repeat TPR_2 PF07719.12 EDO18562.1 - 0.011 15.6 20.2 0.28 11.2 0.0 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO18562.1 - 0.016 14.7 25.1 0.2 11.3 0.2 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat GlgS PF08971.6 EDO18562.1 - 0.034 14.0 0.0 5.6 6.9 0.0 2.8 2 0 0 2 2 2 0 Glycogen synthesis protein TPR_19 PF14559.1 EDO18562.1 - 0.055 13.8 4.5 6.4 7.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EDO18562.1 - 0.087 13.5 10.0 6.2 7.6 0.0 5.3 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EDO18562.1 - 0.15 12.5 7.4 0.26 11.8 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EDO18562.1 - 0.59 10.1 13.3 7.3 6.6 0.1 5.7 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EDO18562.1 - 0.64 9.9 11.9 6.7 6.7 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDO18562.1 - 1.7 8.5 24.1 4.7 7.2 0.0 7.6 8 1 0 8 8 8 0 Tetratricopeptide repeat ENTH PF01417.15 EDO18563.1 - 4.2e-44 149.4 0.1 4.2e-44 149.4 0.1 1.9 2 0 0 2 2 2 1 ENTH domain DNA_ligase_A_M PF01068.16 EDO18564.1 - 7.4e-60 201.7 0.5 1.2e-59 201.0 0.4 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EDO18564.1 - 9.8e-57 191.6 0.1 3e-56 190.0 0.1 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EDO18564.1 - 4.6e-24 84.6 0.0 1.5e-23 83.0 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EDO18564.1 - 0.0024 17.4 0.9 0.77 9.4 0.1 2.5 2 0 0 2 2 2 2 DNA ligase OB-like domain HATPase_c PF02518.21 EDO18566.1 - 8.4e-27 93.0 3.4 9.2e-26 89.7 2.3 2.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EDO18566.1 - 7.2e-26 90.4 0.9 1.6e-25 89.2 0.6 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EDO18566.1 - 2.2e-12 46.7 0.1 6.3e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EDO18566.1 - 0.00042 20.4 4.6 0.35 11.0 0.0 2.9 3 0 0 3 3 3 2 HAMP domain PTPA PF03095.10 EDO18568.1 - 4.4e-112 374.1 0.0 5.3e-112 373.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein UCH PF00443.24 EDO18569.1 - 7.2e-50 169.5 2.5 8.5e-50 169.3 1.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO18569.1 - 6.3e-23 81.6 1.6 1.1e-22 80.8 1.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CW_binding_1 PF01473.15 EDO18569.1 - 0.013 15.5 1.1 0.044 13.8 0.8 2.0 1 0 0 1 1 1 0 Putative cell wall binding repeat Ribosomal_L37e PF01907.14 EDO18569.1 - 0.079 12.7 1.0 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L37e Nudix_N_2 PF14803.1 EDO18569.1 - 0.15 11.7 1.1 9.4 6.0 0.0 2.6 2 0 0 2 2 2 0 Nudix N-terminal DUF678 PF05077.7 EDO18569.1 - 0.33 10.9 3.1 6 6.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF678) UPF0139 PF03669.8 EDO18570.1 - 0.12 11.8 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) DUF2009 PF09418.5 EDO18571.1 - 1.2e-223 742.9 2.8 1.6e-223 742.5 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 EDO18571.1 - 0.00013 21.8 8.7 0.00023 20.9 6.0 1.5 1 0 0 1 1 1 1 B-box zinc finger DUF3873 PF12989.2 EDO18571.1 - 0.12 12.5 1.1 7.1 6.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3873) YqbF PF14553.1 EDO18571.1 - 0.15 11.7 0.3 0.42 10.3 0.2 1.7 1 0 0 1 1 1 0 YqbF, hypothetical protein domain Fer4_6 PF12837.2 EDO18571.1 - 0.67 9.9 9.5 2 8.4 6.6 1.9 1 0 0 1 1 1 0 4Fe-4S binding domain LSM PF01423.17 EDO18572.1 - 5.7e-14 51.4 0.1 7.6e-14 51.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain Ribosomal_S8e PF01201.17 EDO18572.1 - 0.026 14.6 0.5 0.031 14.4 0.4 1.1 1 0 0 1 1 1 0 Ribosomal protein S8e CAP_GLY PF01302.20 EDO18573.1 - 3.8e-22 77.7 0.4 5.8e-22 77.1 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EDO18573.1 - 4e-06 26.9 0.0 6.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain SpoIIIAH PF12685.2 EDO18573.1 - 0.043 13.3 1.2 0.066 12.7 0.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein RNA_pol_3_Rpc31 PF11705.3 EDO18574.1 - 8.2e-69 232.0 14.9 9.1e-69 231.9 10.3 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 SPC25 PF06703.6 EDO18574.1 - 0.12 11.9 0.1 0.47 10.0 0.1 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Tho2 PF11262.3 EDO18575.1 - 2.1e-55 187.8 12.9 2.1e-55 187.8 8.9 4.3 4 1 0 4 4 4 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EDO18575.1 - 2.5e-27 94.4 1.8 3.8e-27 93.8 0.2 2.3 2 0 0 2 2 2 1 Transcription- and export-related complex subunit PIR PF00399.14 EDO18576.1 - 8.4e-15 53.5 16.5 7.6e-08 31.4 4.6 3.0 2 0 0 2 2 2 2 Yeast PIR protein repeat Nefa_Nip30_N PF10187.4 EDO18577.1 - 3.2e-05 24.0 16.9 6.5e-05 23.0 11.7 1.5 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 NDT80_PhoG PF05224.7 EDO18578.1 - 1e-65 221.2 1.3 1e-65 221.2 0.9 2.7 4 0 0 4 4 4 1 NDT80 / PhoG like DNA-binding family CENP-B_dimeris PF09026.5 EDO18578.1 - 2.2 8.5 20.5 2.4 8.4 2.5 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GNAT_acetyltr_2 PF13718.1 EDO18579.1 - 5.1e-81 270.6 0.0 9.7e-81 269.7 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EDO18579.1 - 1.8e-66 223.1 0.1 6.1e-66 221.4 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EDO18579.1 - 5.3e-40 135.0 0.1 1.8e-39 133.3 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EDO18579.1 - 1.6e-39 134.0 1.5 5.3e-39 132.4 1.0 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain DEAD PF00270.24 EDO18579.1 - 0.015 14.7 0.0 0.043 13.3 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase Acetyltransf_7 PF13508.1 EDO18579.1 - 0.092 12.9 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CDP-OH_P_transf PF01066.16 EDO18580.1 - 9.7e-13 48.2 15.9 9.7e-13 48.2 11.0 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase AD PF09793.4 EDO18582.1 - 3.1e-27 94.2 0.0 4.6e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain STN PF07660.9 EDO18582.1 - 0.083 12.4 1.1 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain LSM14 PF12701.2 EDO18582.1 - 0.1 12.4 1.2 0.38 10.5 0.8 1.9 1 1 0 1 1 1 0 Scd6-like Sm domain DUF3402 PF11882.3 EDO18583.1 - 2.1e-86 290.5 12.9 5.6e-85 285.8 9.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EDO18583.1 - 4.6e-77 258.7 1.6 7.8e-77 258.0 1.1 1.4 1 0 0 1 1 1 1 N1221-like protein Spc97_Spc98 PF04130.8 EDO18584.1 - 7.5e-70 235.7 24.5 7.5e-70 235.7 16.9 2.2 2 0 0 2 2 2 2 Spc97 / Spc98 family KapB PF08810.5 EDO18584.1 - 0.058 13.4 1.4 0.12 12.4 0.1 2.1 2 0 0 2 2 2 0 Kinase associated protein B MFS_1 PF07690.11 EDO18585.1 - 2.3e-30 105.5 64.5 7.2e-23 80.8 31.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO18585.1 - 5.3e-07 28.5 22.7 8.3e-07 27.9 3.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter PSD2 PF07624.6 EDO18585.1 - 0.14 11.7 0.7 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Gar1 PF04410.9 EDO18586.1 - 1.5e-43 147.9 2.0 1.5e-43 147.9 1.4 2.8 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region DUF2870 PF11069.3 EDO18586.1 - 0.71 9.9 12.1 0.056 13.4 3.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) PAT1 PF09770.4 EDO18586.1 - 3.8 5.6 71.2 0.015 13.6 42.4 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MutS_V PF00488.16 EDO18587.1 - 6.9e-77 258.0 0.0 1.2e-76 257.2 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EDO18587.1 - 1.1e-35 123.3 1.2 2.8e-35 121.9 0.8 1.8 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EDO18587.1 - 1.1e-25 89.8 0.0 3.1e-25 88.4 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EDO18587.1 - 7.4e-09 35.7 0.2 4.7e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 MutS domain II N-SET PF11764.3 EDO18588.1 - 1.6e-49 167.9 3.6 1.6e-49 167.9 2.5 3.3 5 0 0 5 5 5 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EDO18588.1 - 2.2e-23 81.3 0.1 4.6e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EDO18588.1 - 1.4e-22 80.7 0.2 1.4e-22 80.7 0.2 3.4 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.17 EDO18588.1 - 0.007 15.9 0.0 0.024 14.2 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ORC6 PF05460.8 EDO18589.1 - 4.2e-117 391.2 6.5 4.9e-117 390.9 4.5 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF1980 PF09323.5 EDO18589.1 - 0.0028 17.4 0.8 0.0028 17.4 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1980) CDC45 PF02724.9 EDO18589.1 - 9.7 4.0 12.4 15 3.4 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein PDZ_1 PF12812.2 EDO18590.1 - 8e-52 173.0 0.2 5.8e-36 122.2 0.0 3.4 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.1 EDO18590.1 - 1.6e-14 53.9 0.1 4.2e-12 46.1 0.0 2.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EDO18590.1 - 5.5e-14 51.8 1.3 0.00021 21.1 0.3 4.8 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.19 EDO18590.1 - 1.4e-09 38.0 0.3 0.00012 22.1 0.0 3.0 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EDO18590.1 - 5.6e-06 26.0 0.1 0.035 13.9 0.0 3.0 3 0 0 3 3 3 2 Tricorn protease PDZ domain Trypsin PF00089.21 EDO18590.1 - 5.6e-05 22.8 0.0 0.00019 21.0 0.0 1.8 2 1 0 2 2 2 1 Trypsin DUF31 PF01732.11 EDO18590.1 - 0.0092 15.3 0.2 0.017 14.4 0.1 1.4 1 0 0 1 1 1 1 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 EDO18590.1 - 0.02 14.2 0.2 0.048 13.0 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 EDO18590.1 - 0.16 10.3 0.7 0.4 9.0 0.0 1.8 2 0 0 2 2 2 0 Peptidase S46 TPR_11 PF13414.1 EDO18591.1 - 3.8e-32 109.7 20.1 7e-14 51.2 0.3 6.6 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 EDO18591.1 - 4.5e-21 73.5 22.7 3.3e-05 23.3 0.0 9.6 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.12 EDO18591.1 - 1.2e-17 62.3 26.1 0.00012 21.6 0.1 10.3 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 EDO18591.1 - 6.2e-15 55.4 14.4 0.0097 16.5 0.0 6.4 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EDO18591.1 - 5.8e-14 51.7 19.2 0.00024 20.9 0.1 7.0 7 2 1 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDO18591.1 - 1.2e-13 51.1 13.4 0.0055 17.0 0.2 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDO18591.1 - 3.6e-10 39.5 7.9 3.2 8.6 0.1 8.7 5 2 4 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDO18591.1 - 2.2e-09 36.7 20.1 0.00071 19.5 0.0 9.3 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO18591.1 - 5.5e-09 35.1 33.3 0.025 14.3 0.1 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.1 EDO18591.1 - 1e-06 28.4 1.0 0.52 10.1 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDO18591.1 - 6.5e-06 25.5 15.3 0.44 10.4 0.1 6.9 6 1 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO18591.1 - 1.4e-05 25.1 18.3 0.0066 16.5 0.4 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.5 EDO18591.1 - 0.00047 19.3 2.2 0.027 13.5 0.1 3.3 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like Exonuc_VII_S PF02609.11 EDO18591.1 - 0.0092 15.7 0.8 0.07 12.9 0.6 2.6 1 0 0 1 1 1 1 Exonuclease VII small subunit SHR3_chaperone PF08229.6 EDO18591.1 - 0.026 13.4 1.4 0.08 11.8 1.0 1.8 1 0 0 1 1 1 0 ER membrane protein SH3 PPR PF01535.15 EDO18591.1 - 0.22 11.5 2.9 97 3.2 0.0 5.0 5 0 0 5 5 5 0 PPR repeat DUF2392 PF10288.4 EDO18592.1 - 5.3e-34 116.7 0.7 5.3e-34 116.7 0.5 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2392) DCP2 PF05026.8 EDO18593.1 - 1.9e-32 110.9 0.7 1.9e-32 110.9 0.5 1.9 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 EDO18593.1 - 5.7e-15 55.1 0.0 1.5e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain RhoGAP PF00620.22 EDO18594.1 - 3.8e-37 127.2 0.0 1.3e-36 125.5 0.0 1.9 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EDO18594.1 - 4.6e-08 33.2 0.1 4.6e-08 33.2 0.1 3.0 3 0 0 3 3 3 1 PH domain PX PF00787.19 EDO18594.1 - 6.3e-06 25.9 0.8 2.1e-05 24.2 0.5 1.9 1 0 0 1 1 1 1 PX domain TFIIA PF03153.8 EDO18595.1 - 2.8e-56 192.0 41.7 3e-53 182.0 28.9 2.3 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PEX11 PF05648.9 EDO18596.1 - 8.9e-08 31.6 2.5 3.8e-06 26.3 0.9 2.6 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Methyltransf_12 PF08242.7 EDO18596.1 - 1.3 9.4 4.3 2.7 8.5 0.9 2.4 2 0 0 2 2 2 0 Methyltransferase domain Arginase PF00491.16 EDO18597.1 - 4.2e-74 249.3 0.0 4.8e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family GDPD PF03009.12 EDO18598.1 - 2.8e-82 276.0 0.1 2.8e-82 276.0 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family SPX PF03105.14 EDO18598.1 - 3.2e-26 92.7 29.8 2.4e-18 66.9 5.0 3.6 3 1 1 4 4 4 2 SPX domain Ank_2 PF12796.2 EDO18598.1 - 2.5e-19 69.3 0.0 3.2e-12 46.6 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDO18598.1 - 2.5e-15 55.4 0.0 0.001 18.7 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EDO18598.1 - 1.9e-14 53.3 0.0 0.00015 21.9 0.0 5.0 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO18598.1 - 3.1e-13 48.5 0.1 0.063 13.5 0.0 6.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EDO18598.1 - 4.6e-13 49.2 0.6 1e-05 25.8 0.0 4.2 3 1 1 4 4 4 4 Ankyrin repeats (many copies) ABC1 PF03109.11 EDO18599.1 - 5e-21 74.8 0.0 1.2e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EDO18599.1 - 0.14 11.8 0.0 0.77 9.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family EBV-NA3 PF05009.7 EDO18600.1 - 0.0086 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PDH PF02153.12 EDO18601.1 - 3e-11 42.6 0.0 4.3e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EDO18601.1 - 8.7e-06 25.6 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EDO18601.1 - 4.1e-05 22.8 0.0 8.4e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EDO18601.1 - 5.5e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EDO18601.1 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EDO18601.1 - 0.0029 17.0 0.0 0.0074 15.7 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EDO18601.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EDO18601.1 - 0.059 13.6 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 EDO18601.1 - 0.063 13.2 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain IlvN PF07991.7 EDO18601.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain MRP-S26 PF14943.1 EDO18602.1 - 0.00098 18.7 1.8 0.00098 18.7 1.2 1.7 1 1 1 2 2 2 1 Mitochondrial ribosome subunit S26 Pex24p PF06398.6 EDO18603.1 - 1e-39 136.3 17.2 1.2e-39 136.1 11.9 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HSP70 PF00012.15 EDO18604.1 - 8.5e-182 605.2 13.3 3.1e-181 603.3 9.2 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO18604.1 - 3.4e-10 39.0 0.1 7.1e-10 37.9 0.1 1.4 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 EDO18604.1 - 9.4e-06 25.4 1.5 9.5e-05 22.2 0.1 3.1 2 2 0 2 2 2 1 Cell division protein FtsA Peptidase_M22 PF00814.20 EDO18604.1 - 0.008 15.6 0.2 5.8 6.3 0.0 3.3 3 0 0 3 3 3 1 Glycoprotease family Ketoacyl-synt_C PF02801.17 EDO18604.1 - 0.027 14.3 0.0 0.066 13.0 0.0 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, C-terminal domain RFC1 PF08519.7 EDO18604.1 - 0.028 14.1 0.0 0.093 12.4 0.0 1.9 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Trans_reg_C PF00486.23 EDO18604.1 - 0.086 12.7 0.0 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal GYF PF02213.11 EDO18605.1 - 1.3e-18 66.2 0.4 3.3e-18 64.9 0.3 1.7 1 0 0 1 1 1 1 GYF domain UMP1 PF05348.6 EDO18606.1 - 1.1e-41 141.8 0.1 1.3e-41 141.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 WD40 PF00400.27 EDO18607.1 - 1.1e-30 104.4 19.6 3.9e-08 32.8 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EDO18607.1 - 0.00018 19.8 0.4 0.32 9.0 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EDO18607.1 - 0.00022 20.1 0.2 0.0015 17.3 0.0 2.3 3 1 0 3 3 3 1 Coatomer WD associated region eIF2A PF08662.6 EDO18607.1 - 0.00035 20.3 0.1 0.69 9.5 0.0 3.8 3 1 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A TMC PF07810.8 EDO18607.1 - 0.021 15.2 0.0 0.067 13.6 0.0 1.8 2 0 0 2 2 2 0 TMC domain SUKH_6 PF14568.1 EDO18607.1 - 0.034 14.6 5.7 0.64 10.5 0.5 3.6 3 1 1 4 4 4 0 SMI1-KNR4 cell-wall tRNA-synt_2 PF00152.15 EDO18608.1 - 4e-117 390.7 0.1 4.9e-117 390.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EDO18608.1 - 2.7e-05 23.8 0.1 0.0019 17.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-codon PF01336.20 EDO18608.1 - 0.00086 19.1 0.8 0.0018 18.0 0.6 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EDO18608.1 - 0.0087 15.2 1.3 0.035 13.2 0.0 2.4 2 1 1 3 3 3 1 tRNA synthetases class II core domain (F) PAXNEB PF05625.6 EDO18609.1 - 4.7e-116 387.5 1.2 5.9e-116 387.2 0.8 1.0 1 0 0 1 1 1 1 PAXNEB protein Utp8 PF10395.4 EDO18610.1 - 0.0014 17.0 1.6 0.0017 16.7 1.1 1.0 1 0 0 1 1 1 1 Utp8 family MUG113 PF13455.1 EDO18610.1 - 0.25 11.8 3.8 0.49 10.8 2.6 1.6 1 1 0 1 1 1 0 Meiotically up-regulated gene 113 Lebercilin PF15619.1 EDO18610.1 - 1.7 7.9 11.7 3.2 7.1 1.3 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Romo1 PF10247.4 EDO18611.1 - 1.3e-28 98.9 4.9 1.7e-28 98.6 3.4 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 CYSTM PF12734.2 EDO18611.1 - 0.37 10.9 1.3 0.64 10.1 0.9 1.5 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Abhydrolase_1 PF00561.15 EDO18612.1 - 1.6e-16 60.5 0.0 2.4e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDO18612.1 - 7.5e-11 42.3 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO18612.1 - 0.00027 20.6 0.0 0.0007 19.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EDO18612.1 - 0.044 12.8 0.0 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Sec62 PF03839.11 EDO18613.1 - 9.8e-60 201.7 0.2 9.8e-60 201.7 0.2 1.4 1 1 0 1 1 1 1 Translocation protein Sec62 Claudin_3 PF06653.6 EDO18613.1 - 0.069 12.8 1.8 0.12 12.1 1.2 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF3949 PF13133.1 EDO18613.1 - 0.39 10.9 3.3 1.9 8.7 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3949) MFS_1 PF07690.11 EDO18614.1 - 1.7e-54 184.9 15.9 1.7e-54 184.9 11.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EDO18614.1 - 4.3e-20 71.7 1.2 4.3e-20 71.7 0.8 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter Pyr_redox_2 PF07992.9 EDO18615.1 - 5.1e-42 144.0 0.6 9.3e-42 143.1 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EDO18615.1 - 5.9e-34 116.4 0.3 1.4e-31 108.7 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EDO18615.1 - 1.5e-17 63.7 12.0 2.3e-17 63.1 2.2 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EDO18615.1 - 6.6e-09 36.1 0.1 1.2e-06 28.7 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDO18615.1 - 6.1e-08 31.5 7.6 0.012 14.0 0.0 4.0 3 1 1 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 EDO18615.1 - 7.9e-06 25.0 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 EDO18615.1 - 8.1e-06 25.1 0.0 5.9e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EDO18615.1 - 1.7e-05 23.9 2.9 8.5e-05 21.5 0.3 2.6 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 EDO18615.1 - 8.9e-05 21.5 5.3 0.002 17.1 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EDO18615.1 - 0.00017 21.2 1.5 0.045 13.3 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EDO18615.1 - 0.0083 16.3 0.1 5.7 7.2 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EDO18615.1 - 0.1 11.6 3.2 2.1 7.3 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EDO18615.1 - 0.12 11.7 4.4 1 8.6 3.0 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.19 EDO18615.1 - 0.36 9.6 4.9 0.87 8.3 1.6 2.6 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.13 EDO18615.1 - 1 8.9 4.0 1.4 8.5 0.2 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EDO18615.1 - 2.7 7.1 4.5 2 7.5 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Ribosomal_S6e PF01092.14 EDO18616.1 - 2.1e-61 205.2 0.6 3.7e-61 204.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e SRF-TF PF00319.13 EDO18617.1 - 1.3e-21 75.5 0.1 2.8e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PAP1 PF08601.5 EDO18618.1 - 0.27 10.8 17.8 0.33 10.5 12.4 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SPATIAL PF15256.1 EDO18618.1 - 0.91 9.5 7.8 1.3 9.0 5.4 1.2 1 0 0 1 1 1 0 SPATIAL TFIIA PF03153.8 EDO18618.1 - 2.3 8.0 7.5 2.6 7.8 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_S21 PF00716.12 EDO18618.1 - 3.2 6.9 9.6 4.5 6.5 6.7 1.2 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) DUF966 PF06136.8 EDO18618.1 - 3.4 7.0 12.5 4.4 6.6 8.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Menin PF05053.8 EDO18618.1 - 8 4.5 7.6 12 3.9 5.3 1.2 1 0 0 1 1 1 0 Menin SOG2 PF10428.4 EDO18618.1 - 9.4 4.7 26.6 11 4.4 18.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3827 PF12877.2 EDO18618.1 - 9.8 4.1 11.5 12 3.8 8.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Ceramidase PF05875.7 EDO18619.1 - 5.6e-96 320.7 14.0 6.4e-96 320.5 9.7 1.0 1 0 0 1 1 1 1 Ceramidase CD20 PF04103.10 EDO18619.1 - 0.00093 19.1 2.0 0.00093 19.1 1.4 2.0 2 1 1 3 3 3 1 CD20-like family DUF4181 PF13789.1 EDO18619.1 - 0.005 16.7 3.9 0.017 15.0 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4181) DUF1691 PF07950.6 EDO18619.1 - 0.24 11.3 0.1 0.24 11.3 0.1 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1691) DUF2207 PF09972.4 EDO18619.1 - 2.1 6.8 6.5 0.38 9.2 0.1 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MerC PF03203.9 EDO18619.1 - 2.6 8.4 10.8 2.7 8.3 1.8 2.9 2 1 1 3 3 3 0 MerC mercury resistance protein Sec16_C PF12931.2 EDO18620.1 - 2e-85 286.9 0.0 3.9e-85 286.0 0.0 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EDO18620.1 - 2.7e-16 59.6 0.1 1.8e-15 56.8 0.0 2.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region tRNA_int_end_N2 PF12928.2 EDO18621.1 - 1.8e-19 68.9 0.0 3.5e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Sigma70_ner PF04546.8 EDO18621.1 - 0.013 15.1 2.9 0.013 15.1 2.0 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region SRP72 PF08492.7 EDO18621.1 - 6.7 7.1 10.8 19 5.7 0.7 2.7 2 0 0 2 2 2 0 SRP72 RNA-binding domain AAA PF00004.24 EDO18622.1 - 1.7e-33 115.6 0.0 4.1e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EDO18622.1 - 5.8e-08 33.5 0.0 1.7e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO18622.1 - 5e-07 29.9 0.1 2.1e-06 27.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO18622.1 - 7.2e-07 29.5 0.3 7.2e-06 26.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 EDO18622.1 - 2.5e-06 27.3 0.7 6.8e-06 25.9 0.5 1.8 1 1 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 EDO18622.1 - 9.4e-06 25.2 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EDO18622.1 - 2.7e-05 24.2 0.2 0.00021 21.3 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain AAA_11 PF13086.1 EDO18622.1 - 4.2e-05 23.2 0.0 0.00048 19.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDO18622.1 - 4.3e-05 23.4 0.0 9.6e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO18622.1 - 0.00016 21.5 0.3 0.00057 19.7 0.2 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EDO18622.1 - 0.001 19.1 0.0 0.0043 17.2 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_31 PF13614.1 EDO18622.1 - 0.0019 18.1 2.7 0.055 13.3 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EDO18622.1 - 0.002 18.4 6.7 0.002 18.4 4.6 2.3 2 1 0 2 2 1 1 AAA domain T2SE PF00437.15 EDO18622.1 - 0.0029 16.5 0.0 0.006 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 EDO18622.1 - 0.0057 15.6 0.0 0.009 15.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EDO18622.1 - 0.0057 16.3 0.3 0.17 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EDO18622.1 - 0.0071 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EDO18622.1 - 0.0078 15.9 0.1 0.029 14.0 0.1 2.0 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B RuvB_N PF05496.7 EDO18622.1 - 0.0094 15.0 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 EDO18622.1 - 0.0099 15.5 0.2 0.039 13.6 0.1 2.0 2 0 0 2 2 2 1 NTPase Sigma54_activ_2 PF14532.1 EDO18622.1 - 0.011 15.8 0.0 0.12 12.3 0.0 2.5 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EDO18622.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EDO18622.1 - 0.02 13.7 0.0 0.054 12.3 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EDO18622.1 - 0.021 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EDO18622.1 - 0.025 14.2 0.6 0.093 12.3 0.4 2.1 1 1 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 EDO18622.1 - 0.026 13.6 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 EDO18622.1 - 0.026 14.0 0.0 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EDO18622.1 - 0.029 13.7 0.1 3 7.1 0.0 2.9 2 1 1 3 3 3 0 AAA-like domain AAA_2 PF07724.9 EDO18622.1 - 0.042 13.7 0.0 0.15 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ADK PF00406.17 EDO18622.1 - 0.043 13.6 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase KTI12 PF08433.5 EDO18622.1 - 0.057 12.6 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 EDO18622.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EDO18622.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 EDO18622.1 - 0.085 13.1 2.5 0.2 11.9 0.0 2.6 3 1 0 3 3 2 0 ABC transporter AAA_28 PF13521.1 EDO18622.1 - 0.092 12.7 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDO18622.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF3535 PF12054.3 EDO18623.1 - 2.6e-150 500.9 0.0 1.2e-149 498.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EDO18623.1 - 3.4e-81 272.3 0.1 6.2e-81 271.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EDO18623.1 - 1.1e-18 65.5 1.7 0.024 14.7 0.0 8.1 7 0 0 7 7 7 4 HEAT repeat Helicase_C PF00271.26 EDO18623.1 - 1.8e-13 50.1 0.0 4.8e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_EZ PF13513.1 EDO18623.1 - 3.4e-09 36.8 1.5 0.35 11.4 0.0 7.4 7 0 0 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDO18623.1 - 2.6e-05 24.5 0.0 1.1 9.6 0.0 5.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region DUF1546 PF07571.8 EDO18623.1 - 0.023 14.7 0.6 24 5.1 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1546) Ribosomal_S4 PF00163.14 EDO18624.1 - 2e-26 92.2 1.9 3e-26 91.6 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EDO18624.1 - 1.5e-13 49.9 1.8 1.7e-13 49.7 0.1 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_L21e PF01157.13 EDO18625.1 - 1.9e-45 152.6 6.4 2.3e-45 152.4 4.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.4 EDO18625.1 - 0.0069 15.7 0.1 0.0084 15.4 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 NpwBP PF12622.2 EDO18626.1 - 2.2e-12 47.2 1.6 5.9e-12 45.8 0.0 2.1 2 1 0 2 2 2 1 mRNA biogenesis factor GPI2 PF06432.6 EDO18627.1 - 2.5e-65 220.6 21.6 3e-65 220.3 15.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase 2TM PF13239.1 EDO18627.1 - 5.3 7.1 9.7 14 5.8 0.1 3.3 3 0 0 3 3 3 0 2TM domain WD40 PF00400.27 EDO18628.1 - 5.4e-56 184.5 17.3 3.2e-10 39.5 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EDO18628.1 - 6.7e-32 110.5 2.2 1.4e-31 109.4 1.5 1.6 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EDO18628.1 - 1.4e-07 30.0 0.8 0.0058 14.8 0.0 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 GCR1_C PF12550.3 EDO18629.1 - 2.2e-21 75.4 0.6 2.2e-21 75.4 0.4 2.0 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes AAA PF00004.24 EDO18630.1 - 2.4e-40 137.8 0.0 4.2e-39 133.7 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO18630.1 - 9.8e-06 25.7 0.3 0.0011 19.1 0.1 3.0 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EDO18630.1 - 2.9e-05 23.2 0.0 9e-05 21.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EDO18630.1 - 8.9e-05 22.4 0.1 0.00075 19.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.5 EDO18630.1 - 0.00014 21.6 0.0 0.0076 16.1 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.8 EDO18630.1 - 0.00057 18.7 0.0 0.00057 18.7 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 EDO18630.1 - 0.00078 19.1 0.0 0.0042 16.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EDO18630.1 - 0.00079 18.8 0.0 0.0045 16.4 0.0 2.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_25 PF13481.1 EDO18630.1 - 0.0027 17.1 0.3 0.19 11.0 0.0 2.6 1 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO18630.1 - 0.0032 17.1 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EDO18630.1 - 0.0054 16.6 0.0 0.0054 16.6 0.0 3.0 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.16 EDO18630.1 - 0.0094 15.1 0.1 0.0094 15.1 0.0 2.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EDO18630.1 - 0.029 14.3 0.2 0.98 9.3 0.0 2.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EDO18630.1 - 0.038 14.7 0.0 0.038 14.7 0.0 3.7 4 2 0 4 4 3 0 AAA domain NACHT PF05729.7 EDO18630.1 - 0.084 12.5 3.2 4.5 6.8 0.0 3.5 3 1 1 4 4 4 0 NACHT domain Glyco_transf_15 PF01793.11 EDO18631.1 - 4.1e-121 403.9 8.4 5e-121 403.6 5.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Iso_dh PF00180.15 EDO18632.1 - 6.2e-130 433.1 0.0 7e-130 433.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Aminotran_5 PF00266.14 EDO18633.1 - 4.9e-101 338.1 0.0 6.3e-101 337.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EDO18633.1 - 3.7e-10 39.4 0.0 5.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EDO18633.1 - 2.1e-08 33.5 0.0 4.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EDO18633.1 - 2.1e-06 27.0 0.0 7.6e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EDO18633.1 - 0.00058 18.4 0.0 0.001 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EDO18633.1 - 0.0019 16.5 0.1 0.0033 15.7 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ribosomal_S24e PF01282.14 EDO18633.1 - 0.043 13.6 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S24e Mito_carr PF00153.22 EDO18634.1 - 3.1e-53 177.4 3.8 1.8e-19 69.1 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein AAA_33 PF13671.1 EDO18634.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2036 PF09724.4 EDO18635.1 - 5.4e-82 275.5 0.2 6.3e-82 275.3 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) DEK_C PF08766.6 EDO18635.1 - 0.054 13.2 0.2 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 DEK C terminal domain DUF3507 PF12015.3 EDO18636.1 - 8.4e-68 227.4 2.4 3.4e-67 225.4 1.6 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF2015 PF09435.5 EDO18637.1 - 8.6e-40 135.4 0.8 9.3e-40 135.3 0.5 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF4479 PF14794.1 EDO18637.1 - 0.0024 17.3 0.2 0.0043 16.5 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4479) DUF1325 PF07039.6 EDO18638.1 - 2.9e-33 114.2 0.0 5.1e-33 113.4 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.1 EDO18638.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Peptidase_M27 PF01742.12 EDO18638.1 - 0.015 14.2 1.3 0.015 14.2 0.9 1.5 1 1 1 2 2 2 0 Clostridial neurotoxin zinc protease PilZ PF07238.9 EDO18638.1 - 0.021 14.8 0.0 0.057 13.4 0.0 1.7 1 1 0 1 1 1 0 PilZ domain Asp-B-Hydro_N PF05279.6 EDO18638.1 - 0.024 14.4 2.0 0.036 13.9 1.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Agenet PF05641.7 EDO18638.1 - 0.076 13.1 0.4 4.6 7.4 0.0 2.9 3 0 0 3 3 3 0 Agenet domain Iso_dh PF00180.15 EDO18639.1 - 5.1e-68 229.5 0.0 5.8e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 EDO18639.1 - 0.047 13.7 0.3 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) UPF0052 PF01933.13 EDO18640.1 - 2.7e-61 207.5 0.0 3.4e-61 207.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 ABC_tran PF00005.22 EDO18641.1 - 5.6e-46 156.2 0.0 1e-22 80.8 0.0 4.5 3 2 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EDO18641.1 - 1.7e-17 64.3 1.9 0.0017 18.4 0.0 4.8 5 0 0 5 5 4 4 AAA domain SMC_N PF02463.14 EDO18641.1 - 6.3e-16 58.2 0.1 3.9e-06 26.2 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDO18641.1 - 2.5e-09 36.5 0.0 0.0021 17.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EDO18641.1 - 3.7e-08 34.2 0.0 0.0049 17.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EDO18641.1 - 5e-08 33.1 0.0 0.0019 18.3 0.0 3.8 4 1 0 4 4 3 2 AAA domain AAA_23 PF13476.1 EDO18641.1 - 7.8e-08 32.8 6.0 0.0036 17.6 0.0 3.3 4 0 0 4 4 2 2 AAA domain DUF258 PF03193.11 EDO18641.1 - 1.7e-07 30.5 0.0 0.00081 18.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 EDO18641.1 - 4.9e-07 29.8 0.0 0.014 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EDO18641.1 - 5.9e-07 29.4 0.0 0.0066 16.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EDO18641.1 - 8.6e-07 28.9 0.0 6.2e-05 22.8 0.0 2.9 2 0 0 2 2 2 1 Dynamin family HEAT PF02985.17 EDO18641.1 - 1.8e-06 27.5 0.3 0.031 14.3 0.0 4.5 4 0 0 4 4 3 1 HEAT repeat HEAT_2 PF13646.1 EDO18641.1 - 3.4e-06 27.2 0.0 0.024 14.8 0.0 3.5 1 1 2 3 3 3 2 HEAT repeats AAA_18 PF13238.1 EDO18641.1 - 4.5e-06 26.9 0.0 0.057 13.7 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EDO18641.1 - 4.9e-06 26.1 0.0 0.2 11.0 0.0 3.4 4 0 0 4 4 4 2 AAA-like domain ArgK PF03308.11 EDO18641.1 - 5.6e-06 25.3 0.1 0.069 11.9 0.0 2.4 2 0 0 2 2 2 2 ArgK protein SbcCD_C PF13558.1 EDO18641.1 - 7.8e-06 25.7 0.0 0.01 15.7 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 EDO18641.1 - 8.1e-06 25.9 0.0 0.11 12.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 EDO18641.1 - 1.3e-05 25.0 0.0 0.15 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EDO18641.1 - 1.6e-05 25.3 0.0 0.096 13.1 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 EDO18641.1 - 1.7e-05 25.0 0.0 0.49 10.6 0.0 4.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 EDO18641.1 - 6.4e-05 21.6 0.1 2.1 6.7 0.0 3.6 3 1 0 3 3 3 1 AAA domain MobB PF03205.9 EDO18641.1 - 8.1e-05 22.3 0.0 0.37 10.5 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EDO18641.1 - 0.00012 21.8 0.0 0.55 9.8 0.0 3.0 3 0 0 3 3 2 2 Archaeal ATPase AAA_16 PF13191.1 EDO18641.1 - 0.00013 21.9 0.1 0.19 11.7 0.0 3.4 4 0 0 4 4 3 1 AAA ATPase domain AAA_14 PF13173.1 EDO18641.1 - 0.0002 21.2 0.0 1.2 9.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain MutS_V PF00488.16 EDO18641.1 - 0.00032 20.2 0.0 0.098 12.0 0.0 2.5 2 0 0 2 2 2 1 MutS domain V NACHT PF05729.7 EDO18641.1 - 0.00037 20.1 0.0 0.24 11.0 0.0 2.7 3 0 0 3 3 2 1 NACHT domain ParcG PF10274.4 EDO18641.1 - 0.00065 19.6 0.2 0.32 10.8 0.1 2.5 2 0 0 2 2 2 1 Parkin co-regulated protein PduV-EutP PF10662.4 EDO18641.1 - 0.00065 19.1 0.0 0.36 10.3 0.0 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Vac14_Fab1_bd PF12755.2 EDO18641.1 - 0.0011 19.3 0.0 0.047 14.0 0.0 2.9 2 1 0 3 3 2 1 Vacuolar 14 Fab1-binding region DUF87 PF01935.12 EDO18641.1 - 0.0013 18.6 3.1 0.38 10.5 0.0 4.0 4 0 0 4 4 3 1 Domain of unknown function DUF87 CLASP_N PF12348.3 EDO18641.1 - 0.0013 18.1 0.4 0.013 14.8 0.2 2.5 2 1 0 2 2 1 1 CLASP N terminal AAA_30 PF13604.1 EDO18641.1 - 0.0019 17.8 0.0 2.8 7.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 EDO18641.1 - 0.0035 16.7 0.0 1.8 7.9 0.0 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain HEAT_EZ PF13513.1 EDO18641.1 - 0.01 16.3 1.3 2.6 8.6 0.0 4.8 4 2 2 6 6 5 1 HEAT-like repeat Zeta_toxin PF06414.7 EDO18641.1 - 0.015 14.3 0.0 3.3 6.7 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin CRM1_C PF08767.6 EDO18641.1 - 0.017 14.0 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 CRM1 C terminal T2SE PF00437.15 EDO18641.1 - 0.021 13.7 0.0 0.42 9.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_25 PF13481.1 EDO18641.1 - 0.026 13.9 0.0 8.9 5.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EDO18641.1 - 0.029 13.3 0.0 1.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Septin IstB_IS21 PF01695.12 EDO18641.1 - 0.032 13.6 0.0 11 5.3 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_19 PF13245.1 EDO18641.1 - 0.053 13.2 0.0 5.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain UME PF08064.8 EDO18641.1 - 0.054 13.4 0.3 0.18 11.7 0.2 1.9 1 0 0 1 1 1 0 UME (NUC010) domain FtsK_SpoIIIE PF01580.13 EDO18641.1 - 0.055 12.9 0.1 2.3 7.6 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 EDO18641.1 - 0.064 12.4 0.0 2.9 7.0 0.0 2.9 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.12 EDO18641.1 - 0.078 12.5 0.1 8.4 5.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SNF2_N PF00176.18 EDO18642.1 - 2.9e-42 144.5 0.4 7e-42 143.2 0.3 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EDO18642.1 - 2.5e-10 39.9 9.9 4.6e-10 39.1 5.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDO18642.1 - 6.1e-10 38.6 6.4 1.2e-09 37.6 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO18642.1 - 7.4e-09 35.1 11.5 1.7e-08 33.9 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO18642.1 - 9e-09 35.2 11.5 2.1e-08 34.0 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDO18642.1 - 1.5e-07 31.3 3.9 5.6e-07 29.5 2.7 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EDO18642.1 - 7.1e-06 25.6 10.8 1.6e-05 24.5 7.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EDO18642.1 - 0.00012 21.8 10.3 0.00029 20.6 7.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EDO18642.1 - 0.0019 17.7 3.5 0.0046 16.4 2.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EDO18642.1 - 0.011 15.5 2.1 0.036 13.9 1.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EDO18642.1 - 0.024 14.3 9.2 0.087 12.5 6.4 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 EDO18642.1 - 0.11 12.0 12.9 0.027 13.9 6.2 2.1 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.1 EDO18642.1 - 0.45 10.1 7.9 1.4 8.5 5.5 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EDO18642.1 - 0.47 10.0 4.7 1.3 8.6 3.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EDO18642.1 - 0.64 9.8 6.1 0.15 11.8 1.7 1.9 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Retrotrans_gag PF03732.12 EDO18643.1 - 3.4e-07 30.2 0.0 6.1e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EDO18643.1 - 0.00015 21.5 2.3 0.00024 20.8 1.6 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EDO18643.1 - 0.017 14.6 1.2 0.031 13.7 0.8 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger KorB PF08535.5 EDO18643.1 - 0.036 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 KorB domain RVT_1 PF00078.22 EDO18644.1 - 2.7e-26 92.2 0.1 5.1e-26 91.3 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_A2B PF12384.3 EDO18644.1 - 4.6e-25 87.9 1.1 1.1e-24 86.7 0.7 1.6 1 0 0 1 1 1 1 Ty3 transposon peptidase rve PF00665.21 EDO18644.1 - 4.4e-17 62.3 0.0 1.1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.1 EDO18644.1 - 4e-07 30.4 0.0 9.4e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EDO18644.1 - 0.00012 21.8 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1758 PF05585.7 EDO18644.1 - 0.00025 20.6 0.0 0.0006 19.3 0.0 1.6 1 0 0 1 1 1 1 Putative peptidase (DUF1758) RVP_2 PF08284.6 EDO18644.1 - 0.00094 19.1 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EDO18644.1 - 0.0061 16.4 0.0 0.021 14.7 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease PF09668.5 EDO18644.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease zf-Di19 PF05605.7 EDO18645.1 - 0.0046 17.0 0.1 0.0056 16.7 0.0 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EDO18645.1 - 0.014 15.7 0.9 0.019 15.3 0.6 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-met PF12874.2 EDO18645.1 - 0.016 15.3 0.1 0.024 14.8 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EDO18645.1 - 0.017 15.3 0.3 0.025 14.9 0.2 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met2 PF12907.2 EDO18645.1 - 0.02 14.8 0.2 0.029 14.3 0.1 1.2 1 0 0 1 1 1 0 Zinc-binding Cys_rich_KTR PF14205.1 EDO18645.1 - 0.088 12.2 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Cysteine-rich KTR WD40 PF00400.27 EDO18646.1 - 3.3e-11 42.6 20.4 0.0022 17.8 0.0 8.5 9 1 0 9 9 9 6 WD domain, G-beta repeat Cnd3 PF12719.2 EDO18647.1 - 3.1e-94 315.3 6.4 1e-93 313.6 2.3 2.8 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.17 EDO18647.1 - 5.5e-10 38.4 0.4 0.095 12.8 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 EDO18647.1 - 1.5e-08 34.8 0.1 6e-06 26.4 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EDO18647.1 - 0.0095 16.3 0.2 27 5.3 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EDO18647.1 - 0.087 13.2 1.8 2 8.8 0.2 3.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Swi5 PF07061.6 EDO18648.1 - 4.7e-20 71.1 0.1 5e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 Swi5 GRAM PF02893.15 EDO18649.1 - 1.1e-18 66.5 0.1 2.6e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 GRAM domain Skp1 PF01466.14 EDO18650.1 - 9.2e-37 124.9 0.2 9.2e-37 124.9 0.2 2.2 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EDO18650.1 - 3.8e-13 49.3 0.1 2.1e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Voldacs PF03517.8 EDO18650.1 - 0.035 13.9 3.3 0.058 13.2 2.3 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling BSP_II PF05432.6 EDO18650.1 - 0.056 12.7 2.8 0.069 12.4 1.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.13 EDO18650.1 - 0.34 10.0 5.5 0.43 9.6 3.8 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EDO18650.1 - 0.4 10.1 9.0 0.07 12.6 2.1 2.1 2 0 0 2 2 2 0 Nucleoplasmin DNA_pol_phi PF04931.8 EDO18650.1 - 7.8 4.1 14.4 10 3.7 10.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peroxin-3 PF04882.7 EDO18651.1 - 1.6e-116 389.6 14.3 1.9e-116 389.3 9.9 1.0 1 0 0 1 1 1 1 Peroxin-3 Thioredoxin_7 PF13899.1 EDO18652.1 - 3.4e-20 71.8 0.0 7.9e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EDO18652.1 - 6.2e-17 61.4 0.0 1.3e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EDO18652.1 - 1.1e-13 50.4 0.1 1.1e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain C2-set PF05790.10 EDO18652.1 - 0.014 15.3 0.6 0.03 14.3 0.4 1.6 1 0 0 1 1 1 0 Immunoglobulin C2-set domain DUF2731 PF10806.3 EDO18653.1 - 3.8e-42 143.4 1.9 4.2e-42 143.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) STE PF02200.11 EDO18654.1 - 5e-59 197.2 3.4 8.6e-59 196.4 2.4 1.4 1 0 0 1 1 1 1 STE like transcription factor Tim54 PF11711.3 EDO18654.1 - 1.1 7.7 9.1 0.046 12.3 1.5 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Tcf25 PF04910.9 EDO18655.1 - 2.6e-84 283.2 1.0 2.6e-84 283.2 0.7 2.0 2 0 0 2 2 2 1 Transcriptional repressor TCF25 GAGA_bind PF06217.7 EDO18655.1 - 1.1 9.2 10.4 1.7 8.5 7.2 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family FLO_LFY PF01698.11 EDO18655.1 - 1.9 7.2 9.8 3.6 6.3 6.8 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Rtf2 PF04641.7 EDO18655.1 - 4.7 6.3 18.8 4.1 6.5 12.1 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger Neur_chan_memb PF02932.11 EDO18655.1 - 8.3 6.2 8.1 13 5.5 5.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ipi1_N PF12333.3 EDO18656.1 - 2.7e-29 101.1 0.5 4.1e-28 97.3 0.0 2.5 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HAP1_N PF04849.8 EDO18656.1 - 0.18 10.7 3.7 0.26 10.1 0.1 2.2 2 0 0 2 2 2 0 HAP1 N-terminal conserved region SNF2_N PF00176.18 EDO18657.1 - 3.9e-77 258.9 0.9 1.1e-76 257.5 0.6 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.8 EDO18657.1 - 7.4e-17 60.9 8.7 7.4e-17 60.9 6.0 2.8 1 1 1 2 2 2 2 HSA Helicase_C PF00271.26 EDO18657.1 - 4.8e-14 51.9 0.0 1.6e-13 50.3 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SBDS PF01172.13 EDO18658.1 - 1.1e-16 60.3 0.5 1.2e-16 60.2 0.3 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Gar1 PF04410.9 EDO18659.1 - 4.8e-44 149.5 0.0 4.8e-44 149.5 0.0 2.0 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region Ribosomal_S15 PF00312.17 EDO18660.1 - 9.4e-26 89.3 0.2 2.7e-25 87.9 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein S15 ING PF12998.2 EDO18661.1 - 1.5e-20 73.4 7.6 2.7e-20 72.6 5.3 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EDO18661.1 - 5e-10 38.9 8.3 5e-10 38.9 5.7 1.7 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.1 EDO18661.1 - 0.016 15.3 0.2 0.051 13.7 0.2 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain 4HB_MCP_1 PF12729.2 EDO18661.1 - 0.087 12.1 1.3 0.24 10.7 0.8 1.8 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction EST1_DNA_bind PF10373.4 EDO18661.1 - 0.089 11.9 1.5 0.15 11.2 1.0 1.4 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Fcf1 PF04900.7 EDO18662.1 - 1.1e-37 128.1 0.1 1.1e-37 128.1 0.1 1.5 2 0 0 2 2 2 1 Fcf1 LRR_4 PF12799.2 EDO18663.1 - 0.012 15.1 1.1 0.029 14.0 0.8 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) DUF3627 PF12299.3 EDO18663.1 - 0.081 12.9 0.7 0.37 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) Rpp20 PF12328.3 EDO18665.1 - 0.016 14.8 1.3 0.031 13.9 0.9 1.5 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P FlxA PF14282.1 EDO18665.1 - 0.11 12.4 12.5 0.2 11.6 8.6 1.4 1 0 0 1 1 1 0 FlxA-like protein zf-CCHC PF00098.18 EDO18665.1 - 0.71 9.9 4.4 0.25 11.3 1.0 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDO18665.1 - 4.4 7.0 7.9 0.48 10.1 0.9 2.5 2 0 0 2 2 2 0 Zinc knuckle bZIP_1 PF00170.16 EDO18667.1 - 2.5e-06 27.3 17.4 5.2e-06 26.3 12.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 EDO18667.1 - 0.012 15.2 3.4 0.034 13.7 2.3 1.7 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_2 PF07716.10 EDO18667.1 - 0.31 10.8 16.8 0.72 9.7 11.6 1.6 1 0 0 1 1 1 0 Basic region leucine zipper CENP-C_C PF11699.3 EDO18668.1 - 1.7e-28 98.3 1.9 3.6e-28 97.3 1.3 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 EDO18668.1 - 1.6e-20 74.0 4.2 1.6e-20 74.0 2.9 3.9 3 0 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 EDO18668.1 - 1.4e-05 24.5 0.0 2.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.13 EDO18668.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase AT_hook PF02178.14 EDO18668.1 - 0.47 10.3 6.4 1.4 8.8 4.4 1.9 1 0 0 1 1 1 0 AT hook motif Pkinase PF00069.20 EDO18669.1 - 5e-71 238.9 0.0 1.1e-70 237.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18669.1 - 1.4e-46 158.7 0.0 2.5e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EDO18669.1 - 4.1e-23 81.5 0.4 3.4e-22 78.6 0.0 2.9 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EDO18669.1 - 2.6e-05 23.3 0.0 4.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EDO18669.1 - 0.14 11.8 0.0 1.1 8.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family HGTP_anticodon2 PF12745.2 EDO18670.1 - 5.3e-98 327.5 4.0 5.3e-98 327.5 2.8 3.7 4 0 0 4 4 4 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EDO18670.1 - 4.1e-69 232.6 1.9 2.5e-43 148.0 0.0 4.4 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18670.1 - 1.3e-35 122.7 0.3 1.2e-20 73.7 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EDO18670.1 - 1e-13 51.1 2.7 4e-13 49.2 1.8 2.1 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EDO18670.1 - 1e-12 47.7 0.1 2.9e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 EDO18670.1 - 0.0038 16.2 0.0 0.085 11.8 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDO18670.1 - 0.013 15.2 0.1 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3246 PF11596.3 EDO18670.1 - 0.87 8.8 11.4 1.8 7.8 7.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) PAP2 PF01569.16 EDO18671.1 - 1.6e-20 73.0 1.8 1.6e-20 73.0 1.3 2.2 2 1 0 2 2 2 1 PAP2 superfamily MerC PF03203.9 EDO18671.1 - 0.079 13.3 1.3 0.35 11.2 0.3 2.1 1 1 1 2 2 2 0 MerC mercury resistance protein 7TMR-DISM_7TM PF07695.6 EDO18671.1 - 7.2 6.2 19.4 0.15 11.7 4.2 2.6 3 0 0 3 3 3 0 7TM diverse intracellular signalling TMF_TATA_bd PF12325.3 EDO18672.1 - 0.0084 15.8 1.7 0.0084 15.8 1.1 7.6 1 1 7 8 8 8 2 TATA element modulatory factor 1 TATA binding COMP PF11598.3 EDO18672.1 - 0.022 14.8 0.7 0.54 10.3 0.0 3.0 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein AAA_13 PF13166.1 EDO18672.1 - 0.12 10.7 107.5 0.36 9.2 27.5 3.2 2 1 1 3 3 3 0 AAA domain DUF836 PF05768.9 EDO18673.1 - 2.8e-16 59.5 0.4 3.8e-16 59.1 0.3 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 EDO18673.1 - 0.0092 16.1 0.7 0.012 15.8 0.5 1.3 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.19 EDO18673.1 - 0.057 13.4 0.6 0.1 12.5 0.4 1.6 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_4 PF13462.1 EDO18673.1 - 0.084 12.8 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin HisG PF01634.13 EDO18674.1 - 2.9e-56 189.5 0.6 4.5e-56 188.9 0.4 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EDO18674.1 - 4.6e-25 87.3 0.0 9.9e-25 86.2 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain FUN14 PF04930.10 EDO18675.1 - 8.2e-07 29.2 0.2 1.2e-06 28.7 0.2 1.4 1 0 0 1 1 1 1 FUN14 family UCH PF00443.24 EDO18676.1 - 2.1e-54 184.4 5.6 5.2e-54 183.1 3.9 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Tom37_C PF11801.3 EDO18676.1 - 4.2 7.2 13.2 0.14 12.0 1.2 3.5 3 1 0 3 3 3 0 Tom37 C-terminal domain Phosphoprotein PF00922.12 EDO18677.1 - 0.018 14.2 1.5 0.023 13.9 0.8 1.3 1 1 0 1 1 1 0 Vesiculovirus phosphoprotein DUF1913 PF08931.5 EDO18677.1 - 0.091 12.5 1.2 1.3 8.8 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1913) SWIM PF04434.12 EDO18677.1 - 0.55 9.7 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 0 SWIM zinc finger PET122 PF05476.6 EDO18678.1 - 2e-122 407.6 3.9 2.6e-122 407.2 2.7 1.1 1 0 0 1 1 1 1 PET122 DASH_Spc34 PF08657.5 EDO18678.1 - 0.093 12.3 1.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 DASH complex subunit Spc34 60KD_IMP PF02096.15 EDO18679.1 - 1.1e-34 119.8 0.6 1.1e-34 119.8 0.4 2.1 2 0 0 2 2 2 1 60Kd inner membrane protein RhoGAP PF00620.22 EDO18680.1 - 7.7e-40 135.9 0.4 6.4e-38 129.7 0.0 2.9 2 0 0 2 2 2 1 RhoGAP domain RasGEF PF00617.14 EDO18680.1 - 1.9e-22 79.9 3.0 1.9e-22 79.9 2.1 4.6 5 0 0 5 5 5 1 RasGEF domain RasGEF_N PF00618.15 EDO18680.1 - 3e-15 56.1 2.7 3e-15 56.1 1.9 5.3 7 0 0 7 7 7 1 RasGEF N-terminal motif PH PF00169.24 EDO18680.1 - 0.00012 22.2 1.4 0.002 18.3 0.0 3.2 2 1 0 2 2 2 1 PH domain Tbf5 PF06331.7 EDO18681.1 - 5.6e-29 99.7 0.3 6.3e-29 99.5 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 YokU PF14122.1 EDO18681.1 - 0.065 12.9 0.1 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 YokU-like protein NDUF_B5 PF09781.4 EDO18681.1 - 0.12 11.6 0.1 0.14 11.3 0.0 1.3 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit Clathrin PF00637.15 EDO18682.1 - 7.1e-28 97.0 2.8 7.1e-28 97.0 1.9 4.0 2 1 1 4 4 4 1 Region in Clathrin and VPS Vps39_1 PF10366.4 EDO18682.1 - 0.00028 20.8 0.3 0.00028 20.8 0.2 3.0 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 TPR_17 PF13431.1 EDO18682.1 - 0.0036 17.3 0.0 0.021 14.9 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat WD40 PF00400.27 EDO18682.1 - 0.01 15.7 2.0 0.063 13.1 1.1 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat PPR_3 PF13812.1 EDO18682.1 - 0.061 13.6 0.0 17 6.0 0.0 2.8 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DDE_1 PF03184.14 EDO18683.1 - 2.8e-69 232.5 2.1 6.4e-69 231.4 1.4 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EDO18683.1 - 1.9e-09 37.2 0.7 1.9e-09 37.2 0.5 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF846 PF05832.7 EDO18684.1 - 1.5e-46 157.6 6.0 2.1e-46 157.1 4.2 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Mt_ATP-synt_B PF05405.9 EDO18685.1 - 0.035 13.5 1.6 0.23 10.9 0.4 2.4 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SSF PF00474.12 EDO18686.1 - 5.4e-07 28.5 32.3 1.7e-06 26.9 22.4 1.7 1 1 0 1 1 1 1 Sodium:solute symporter family CBFD_NFYB_HMF PF00808.18 EDO18687.1 - 6.9e-11 42.0 0.1 9.5e-11 41.5 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3410 PF11890.3 EDO18687.1 - 0.13 11.9 0.1 0.35 10.5 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3410) SecE PF00584.15 EDO18688.1 - 1.1e-11 44.0 0.0 1.3e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Coiled-coil_56 PF09813.4 EDO18688.1 - 0.041 13.8 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 DUF3944 PF13099.1 EDO18688.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) CBFD_NFYB_HMF PF00808.18 EDO18689.1 - 6e-05 23.0 0.0 8.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SecE PF00584.15 EDO18690.1 - 1.1e-11 44.0 0.0 1.3e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Coiled-coil_56 PF09813.4 EDO18690.1 - 0.039 13.9 0.0 0.046 13.7 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 DUF3944 PF13099.1 EDO18690.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3944) Nop52 PF05997.7 EDO18691.1 - 9.6e-72 240.9 7.6 1.1e-71 240.6 5.3 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 EDO18691.1 - 0.00076 19.2 0.2 0.016 14.9 0.1 2.4 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair UBN2 PF14223.1 EDO18693.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type OB_NTP_bind PF07717.11 EDO18694.1 - 2.7e-22 78.7 0.0 7.5e-22 77.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 EDO18694.1 - 8.7e-14 51.3 1.9 3.7e-13 49.3 1.3 2.2 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EDO18694.1 - 2.3e-11 43.4 0.8 7.5e-11 41.8 0.2 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO18694.1 - 9.6e-10 38.1 1.5 1.6e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.18 EDO18694.1 - 1.8e-09 37.5 0.0 1.8e-09 37.5 0.0 3.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) AAA_22 PF13401.1 EDO18694.1 - 4.9e-05 23.4 0.0 0.00036 20.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDO18694.1 - 0.00049 19.5 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EDO18694.1 - 0.0027 16.6 0.0 0.0073 15.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 EDO18694.1 - 0.0067 15.5 0.1 0.043 12.9 0.0 2.4 3 0 0 3 3 3 1 KaiC PhoH PF02562.11 EDO18694.1 - 0.008 15.4 0.2 0.06 12.5 0.1 2.5 2 1 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EDO18694.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EDO18694.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zot PF05707.7 EDO18694.1 - 0.013 14.9 0.1 0.064 12.7 0.1 2.2 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_16 PF13191.1 EDO18694.1 - 0.049 13.6 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EDO18694.1 - 0.18 11.1 0.0 0.45 9.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO18694.1 - 0.93 9.8 11.8 0.64 10.3 0.1 4.3 4 0 0 4 4 3 0 AAA domain CDC73 PF05179.9 EDO18695.1 - 1.1e-73 248.0 6.9 1.3e-73 247.7 4.8 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family EAP30 PF04157.11 EDO18696.1 - 1.9e-41 141.6 0.8 3.4e-41 140.8 0.6 1.4 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EDO18696.1 - 7.1e-34 115.4 0.1 1.9e-33 114.1 0.1 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EDO18696.1 - 2.9e-05 23.4 0.0 9e-05 21.9 0.0 1.9 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 EDO18696.1 - 0.0026 17.2 0.1 0.0026 17.2 0.1 3.0 3 0 0 3 3 3 1 Sec23/Sec24 zinc finger bPH_3 PF14470.1 EDO18696.1 - 0.0049 17.0 0.1 0.024 14.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial PH domain DZR PF12773.2 EDO18696.1 - 0.027 14.2 1.2 0.027 14.2 0.8 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf-RanBP PF00641.13 EDO18696.1 - 0.072 12.2 10.7 0.036 13.1 1.0 3.2 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.1 EDO18696.1 - 1.9 7.7 14.0 0.18 11.0 2.3 2.6 2 1 0 2 2 2 0 zinc-ribbon domain ABC_membrane_2 PF06472.10 EDO18697.1 - 1.3e-65 221.2 8.9 2.5e-42 144.9 0.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EDO18697.1 - 5e-19 68.9 0.7 5.1e-17 62.4 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EDO18697.1 - 3.2e-06 27.3 0.1 3.2e-06 27.3 0.1 4.5 4 1 1 5 5 5 1 AAA domain AAA_29 PF13555.1 EDO18697.1 - 0.015 14.8 0.0 0.059 12.8 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EDO18697.1 - 0.042 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain SUR7 PF06687.7 EDO18698.1 - 6.3e-39 133.7 9.3 7.7e-39 133.4 6.4 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EDO18698.1 - 0.00015 21.5 1.6 0.00015 21.5 1.1 1.7 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2663 PF10864.3 EDO18698.1 - 0.0011 19.1 0.7 0.0085 16.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2663) Wzy_C PF04932.10 EDO18698.1 - 0.11 12.2 5.5 1.8 8.3 1.9 2.2 2 0 0 2 2 2 0 O-Antigen ligase DUF1700 PF08006.6 EDO18698.1 - 2.5 7.3 8.6 0.14 11.4 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) DUF1212 PF06738.7 EDO18698.1 - 9 5.7 8.6 5.8 6.3 3.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) SUR7 PF06687.7 EDO18699.1 - 2.8e-15 56.4 14.8 5.9e-14 52.1 10.3 2.7 1 1 0 1 1 1 1 SUR7/PalI family GATA PF00320.22 EDO18700.1 - 8e-11 41.1 9.7 3.4e-10 39.1 6.7 2.2 1 0 0 1 1 1 1 GATA zinc finger Cas_CXXC_CXXC PF09706.5 EDO18700.1 - 0.17 12.0 3.3 2 8.6 0.1 2.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) Orn_Arg_deC_N PF02784.11 EDO18701.1 - 5.7e-75 251.7 0.0 7.6e-75 251.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EDO18701.1 - 1.8e-31 108.2 0.1 3.2e-31 107.4 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Voldacs PF03517.8 EDO18702.1 - 1.4e-13 50.8 0.2 2.1e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Acyl_transf_1 PF00698.16 EDO18703.1 - 1.1e-91 307.4 0.0 5.4e-91 305.2 0.0 2.2 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EDO18703.1 - 1.1e-35 121.7 0.0 2e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EDO18703.1 - 1.3e-28 98.5 0.1 3.1e-28 97.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EDO18703.1 - 8.9e-15 54.6 0.0 2.2e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EDO18703.1 - 0.00026 20.2 0.0 0.0028 16.8 0.0 2.5 1 1 0 1 1 1 1 Nitronate monooxygenase SRR1 PF07985.7 EDO18704.1 - 2.5e-18 65.7 0.1 4.2e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 SRR1 Pribosyltran_N PF13793.1 EDO18705.1 - 1.4e-38 131.2 0.0 4.1e-38 129.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EDO18705.1 - 1.8e-38 132.1 1.9 2.4e-30 105.6 0.2 2.2 1 1 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EDO18705.1 - 1.2e-06 28.2 0.4 2.4e-05 24.0 0.3 2.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EDO18705.1 - 0.04 13.1 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase His_Phos_2 PF00328.17 EDO18706.1 - 8.8e-127 423.1 0.2 1.4e-126 422.5 0.2 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EDO18706.1 - 1.9e-09 37.2 0.0 4.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EDO18706.1 - 0.0038 17.1 0.3 0.031 14.1 0.0 2.5 2 1 0 2 2 2 1 ATP-grasp domain Utp21 PF04192.7 EDO18707.1 - 4.4e-82 274.7 0.3 6.4e-82 274.2 0.2 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EDO18707.1 - 3.1e-23 80.7 13.4 1.8e-08 33.9 0.2 8.4 8 0 0 8 8 8 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EDO18707.1 - 1.9e-07 30.8 0.0 0.00033 20.1 0.0 3.3 2 1 0 2 2 2 2 PQQ-like domain eIF2A PF08662.6 EDO18707.1 - 1.3e-06 28.2 2.0 0.017 14.8 0.0 4.5 2 2 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.10 EDO18707.1 - 3.7e-05 22.9 2.1 0.054 12.5 0.0 3.6 4 0 0 4 4 4 2 CPSF A subunit region Apc4_WD40 PF12894.2 EDO18707.1 - 0.00022 20.6 0.0 0.021 14.3 0.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.1 EDO18707.1 - 0.00045 19.9 0.6 3 7.6 0.0 3.9 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 EDO18707.1 - 0.0012 17.2 0.0 0.0031 15.8 0.0 1.6 2 0 0 2 2 2 1 Cytochrome D1 heme domain Neisseria_PilC PF05567.6 EDO18707.1 - 0.042 12.8 0.0 0.087 11.8 0.0 1.4 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain PQQ_3 PF13570.1 EDO18707.1 - 0.055 13.7 0.4 1.9 8.8 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain Vps39_1 PF10366.4 EDO18708.1 - 8.7e-30 102.9 3.0 8.7e-30 102.9 2.1 3.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EDO18708.1 - 1.2e-14 54.4 2.2 2e-14 53.7 0.2 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EDO18708.1 - 0.00016 21.3 20.2 0.017 14.7 0.3 5.1 3 2 2 5 5 5 2 Region in Clathrin and VPS TerY-C PF15616.1 EDO18708.1 - 0.088 12.7 0.2 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 TerY-C metal binding domain Cut8_M PF14483.1 EDO18709.1 - 0.058 13.2 0.9 5.3 6.9 0.0 2.6 3 0 0 3 3 3 0 Cut8 dimerisation domain EFhand_Ca_insen PF08726.5 EDO18709.1 - 0.074 13.0 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Ca2+ insensitive EF hand CENP-B_N PF04218.8 EDO18709.1 - 0.62 9.5 3.1 2.6 7.5 0.0 3.0 3 0 0 3 3 3 0 CENP-B N-terminal DNA-binding domain Rxt3 PF08642.5 EDO18710.1 - 1.6e-28 99.2 0.1 7.3e-28 97.1 0.0 2.0 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 Ribosomal_L31e PF01198.14 EDO18711.1 - 1.1e-35 121.1 1.3 1.3e-35 120.9 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Dus PF01207.12 EDO18712.1 - 3.4e-81 272.4 0.0 4.2e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 EDO18712.1 - 0.11 11.4 0.0 0.37 9.7 0.0 1.7 1 1 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family BRE1 PF08647.6 EDO18713.1 - 3.9e-30 103.6 16.3 3.9e-30 103.6 11.3 6.5 3 1 2 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 EDO18713.1 - 1.1e-05 24.9 10.7 2.2e-05 24.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO18713.1 - 1.3e-05 25.0 13.1 2.6e-05 24.1 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO18713.1 - 5.1e-05 22.9 13.2 0.0001 21.9 9.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO18713.1 - 5.2e-05 22.8 12.8 0.00011 21.7 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO18713.1 - 0.002 17.9 10.8 0.0039 16.9 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 EDO18713.1 - 0.0025 17.2 5.2 0.0053 16.2 3.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rtf2 PF04641.7 EDO18713.1 - 0.0026 17.0 3.8 0.0026 17.0 2.6 4.2 1 1 2 4 4 2 1 Rtf2 RING-finger zf-C2H2 PF00096.21 EDO18713.1 - 0.01 16.1 0.2 0.01 16.1 0.2 2.8 3 0 0 3 3 1 0 Zinc finger, C2H2 type bZIP_1 PF00170.16 EDO18713.1 - 0.014 15.3 0.9 0.014 15.3 0.6 9.4 8 2 2 10 10 10 0 bZIP transcription factor zf-RING_6 PF14835.1 EDO18713.1 - 0.11 12.2 5.2 0.23 11.2 3.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EDO18713.1 - 0.14 11.9 7.6 0.52 10.0 5.3 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EDO18713.1 - 4.3 7.0 9.7 9.7 5.8 6.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2H2_jaz PF12171.3 EDO18714.1 - 0.00015 21.8 4.6 0.1 12.7 0.0 3.0 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EDO18714.1 - 0.00073 19.6 14.1 0.038 14.3 0.3 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO18714.1 - 0.0089 16.2 15.3 0.032 14.5 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EDO18714.1 - 0.012 15.8 20.6 0.049 13.9 0.7 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type Bap31 PF05529.7 EDO18715.1 - 1.8e-47 161.2 13.1 1.9e-46 157.9 9.1 1.9 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like ADIP PF11559.3 EDO18715.1 - 0.0089 15.9 1.2 0.016 15.1 0.8 1.5 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF4446 PF14584.1 EDO18715.1 - 0.69 9.7 4.7 0.2 11.5 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Wzy_C PF04932.10 EDO18715.1 - 1 9.1 3.4 1.8 8.3 2.3 1.5 1 1 0 1 1 1 0 O-Antigen ligase Bromodomain PF00439.20 EDO18716.1 - 1.4e-41 140.2 2.7 1e-20 73.3 0.2 2.7 2 0 0 2 2 2 2 Bromodomain DSHCT PF08148.7 EDO18717.1 - 1.4e-60 203.6 0.2 3.3e-60 202.4 0.2 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EDO18717.1 - 1.3e-22 80.1 0.1 2.8e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO18717.1 - 1.1e-07 31.5 0.0 2.5e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EDO18717.1 - 4.8e-06 25.9 0.7 1.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 rRNA-processing arch domain ResIII PF04851.10 EDO18717.1 - 0.00099 18.9 0.1 0.0039 17.0 0.1 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Translin PF01997.11 EDO18717.1 - 0.036 13.6 3.1 0.075 12.6 0.0 2.9 3 1 0 3 3 3 0 Translin family Ribonuclease_3 PF00636.21 EDO18718.1 - 0.11 12.9 0.8 0.24 11.8 0.6 1.7 1 1 0 1 1 1 0 Ribonuclease III domain COX7C PF02935.11 EDO18720.1 - 2e-23 81.9 1.2 4.4e-23 80.8 0.8 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Iso_dh PF00180.15 EDO18721.1 - 2.6e-67 227.2 0.0 3.1e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ATP-synt_10 PF05176.9 EDO18722.1 - 1.3e-87 293.2 2.0 1.6e-87 292.9 1.4 1.0 1 0 0 1 1 1 1 ATP10 protein Arrestin_N PF00339.24 EDO18723.1 - 6.5e-07 29.2 0.1 3.4e-06 26.9 0.0 2.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain RTP PF02334.11 EDO18723.1 - 0.026 14.4 0.1 0.06 13.3 0.1 1.6 1 0 0 1 1 1 0 Replication terminator protein CFEM PF05730.6 EDO18724.1 - 3.3e-08 33.2 15.4 9.5e-08 31.7 10.7 1.8 1 0 0 1 1 1 1 CFEM domain DUF605 PF04652.11 EDO18724.1 - 0.031 13.6 28.3 0.038 13.4 19.6 1.0 1 0 0 1 1 1 0 Vta1 like KAR9 PF08580.5 EDO18724.1 - 1.5 6.9 31.1 1.9 6.6 21.6 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Herpes_TAF50 PF03326.8 EDO18724.1 - 2 7.2 30.6 2.4 6.9 21.2 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF936 PF06075.7 EDO18724.1 - 5 5.9 28.1 5.9 5.6 19.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Peptidase_S64 PF08192.6 EDO18724.1 - 9.6 4.3 24.4 12 4.1 16.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_M16 PF00675.15 EDO18726.1 - 2.3e-39 134.5 0.3 1.6e-38 131.8 0.3 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDO18726.1 - 1.1e-28 100.1 1.4 2.1e-15 56.8 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Ribosomal_S14 PF00253.16 EDO18727.1 - 1.6e-17 62.5 5.1 1.8e-17 62.4 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 EDO18727.1 - 0.15 12.1 1.7 4.4 7.4 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2296 PF10058.4 EDO18727.1 - 0.15 11.7 2.2 9.4 6.0 2.2 2.1 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-C2H2_2 PF12756.2 EDO18728.1 - 5.2e-30 103.5 7.8 8e-29 99.7 0.5 2.7 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EDO18728.1 - 4.2 7.6 10.0 0.4 10.8 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding BIR PF00653.16 EDO18728.1 - 5.1 7.5 7.0 2.2 8.7 0.2 2.8 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain Vac14_Fig4_bd PF11916.3 EDO18729.1 - 7.5e-71 237.0 4.6 7.5e-71 237.0 3.2 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EDO18729.1 - 1.1e-49 166.7 1.4 9.9e-39 131.6 0.0 4.9 5 0 0 5 5 5 3 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EDO18729.1 - 1.8e-11 43.0 4.7 0.00023 20.9 0.0 7.2 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 EDO18729.1 - 3.4e-09 36.8 1.5 0.0066 16.6 0.0 5.6 5 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EDO18729.1 - 1.5e-08 34.8 0.5 0.074 13.5 0.0 7.4 7 1 0 8 8 8 1 HEAT-like repeat CLASP_N PF12348.3 EDO18729.1 - 2.4e-08 33.6 0.6 0.0082 15.5 0.0 4.4 3 1 1 4 4 4 2 CLASP N terminal RIX1 PF08167.7 EDO18729.1 - 0.0082 15.8 0.7 3.2 7.4 0.1 3.5 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis Sigma70_r2 PF04542.9 EDO18729.1 - 0.027 14.0 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-70 region 2 Arm PF00514.18 EDO18729.1 - 0.12 12.2 3.1 2 8.3 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Phage_int_SAM_4 PF13495.1 EDO18730.1 - 0.12 12.6 0.0 0.35 11.2 0.0 1.7 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Rad52_Rad22 PF04098.10 EDO18731.1 - 1.5e-16 60.5 0.1 1.8e-16 60.2 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein tRNA-synt_1 PF00133.17 EDO18732.1 - 6.9e-58 196.0 0.0 2.3e-19 68.8 0.0 6.0 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EDO18732.1 - 1.7e-38 131.7 0.0 3.2e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EDO18732.1 - 7.4e-31 107.1 1.1 1e-22 80.3 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1d PF00750.14 EDO18732.1 - 5.9e-06 25.3 0.0 9.5e-06 24.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EDO18732.1 - 0.00032 19.9 0.0 0.019 14.1 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF4257 PF14074.1 EDO18733.1 - 0.0044 16.6 0.9 0.008 15.8 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4257) adh_short PF00106.20 EDO18734.1 - 9.8e-17 61.3 0.0 1.4e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO18734.1 - 4.7e-09 36.1 0.0 6.7e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EDO18734.1 - 0.001 19.1 0.0 0.01 15.8 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EDO18734.1 - 0.007 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Alg14 PF08660.6 EDO18735.1 - 0.038 13.9 0.2 0.042 13.8 0.1 1.1 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like MFMR PF07777.6 EDO18735.1 - 4.8 7.0 6.7 6.7 6.5 4.7 1.1 1 0 0 1 1 1 0 G-box binding protein MFMR CAF1 PF04857.15 EDO18736.1 - 9.4e-54 182.4 1.8 1.4e-53 181.9 1.3 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease NTF2 PF02136.15 EDO18737.1 - 4.9e-21 75.2 0.5 1.7e-20 73.5 0.0 2.1 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EDO18737.1 - 0.019 14.5 0.2 0.052 13.1 0.1 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Y_phosphatase2 PF03162.8 EDO18738.1 - 1.7e-37 128.3 2.1 4.1e-36 123.8 1.5 2.4 1 1 0 1 1 1 1 Tyrosine phosphatase family Saccharop_dh PF03435.13 EDO18739.1 - 2.5e-128 428.3 0.0 3.4e-128 427.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EDO18739.1 - 3.5e-07 30.4 0.1 5.8e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EDO18739.1 - 3.1e-05 24.0 0.1 4.7e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EDO18739.1 - 0.0096 14.6 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EDO18739.1 - 0.034 13.3 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_7 PF13241.1 EDO18739.1 - 0.079 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2325 PF10087.4 EDO18739.1 - 0.099 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Mso1_Sec1_bdg PF14475.1 EDO18740.1 - 9.5e-19 66.5 0.0 1.8e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 CDC50 PF03381.10 EDO18741.1 - 1.3e-91 306.6 1.7 1.6e-91 306.3 1.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Not1 PF04054.10 EDO18742.1 - 2.8e-73 246.9 11.5 2.8e-73 246.9 7.9 2.7 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EDO18742.1 - 0.021 14.5 0.0 0.021 14.5 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3819) Pkinase PF00069.20 EDO18743.1 - 5.6e-75 251.8 0.1 1.2e-74 250.7 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18743.1 - 3.7e-33 114.6 0.1 4e-32 111.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO18743.1 - 1.9e-08 33.6 0.2 6.3e-06 25.3 0.0 2.6 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EDO18743.1 - 0.11 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO18743.1 - 0.14 11.8 0.0 10 5.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Trm112p PF03966.11 EDO18744.1 - 8.6e-18 64.4 0.0 1.2e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein zf-BED PF02892.10 EDO18744.1 - 0.084 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 BED zinc finger HA2 PF04408.18 EDO18745.1 - 0.092 12.7 1.4 0.21 11.6 0.1 2.1 2 0 0 2 2 2 0 Helicase associated domain (HA2) DUF866 PF05907.8 EDO18746.1 - 4.5e-27 94.5 11.1 3.8e-24 85.0 7.7 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-PHD-like PF15446.1 EDO18746.1 - 0.059 12.6 0.3 0.059 12.6 0.2 1.8 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Lar_restr_allev PF14354.1 EDO18746.1 - 0.19 12.0 3.0 2.7 8.3 0.0 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar Elf1 PF05129.8 EDO18746.1 - 0.28 10.9 8.8 5.7 6.7 0.0 3.1 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like Cytochrom_c3_2 PF14537.1 EDO18746.1 - 5 7.5 7.1 7.5 6.9 0.1 2.3 1 1 1 2 2 2 0 Cytochrome c3 Flocculin_t3 PF13928.1 EDO18747.1 - 5.9e-15 55.1 63.5 7.9e-08 32.3 11.2 19.4 11 4 4 15 15 15 4 Flocculin type 3 repeat zf-LYAR PF08790.6 EDO18748.1 - 1.3e-13 50.3 8.6 1.3e-13 50.3 6.0 1.7 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF3306 PF11748.3 EDO18748.1 - 0.0091 16.6 7.0 0.012 16.2 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3306) NHS PF15273.1 EDO18748.1 - 0.089 11.4 10.2 0.097 11.2 7.1 1.1 1 0 0 1 1 1 0 NHS-like DUF2201_N PF13203.1 EDO18748.1 - 0.27 10.3 10.4 0.32 10.1 7.2 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain zf-C2H2 PF00096.21 EDO18748.1 - 0.38 11.2 6.3 1.1 9.7 1.0 2.5 1 1 1 2 2 2 0 Zinc finger, C2H2 type DUF908 PF06012.7 EDO18748.1 - 0.77 9.0 9.0 0.88 8.8 6.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Hid1 PF12722.2 EDO18748.1 - 1.4 6.5 13.4 1.5 6.3 9.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EDO18748.1 - 2.5 6.0 12.3 3 5.7 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 EDO18748.1 - 2.8 7.6 8.8 3.2 7.4 6.1 1.3 1 0 0 1 1 1 0 DDHD domain DUF4175 PF13779.1 EDO18748.1 - 2.9 5.4 18.2 3.4 5.2 12.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ATAD4 PF15321.1 EDO18748.1 - 3.2 8.8 14.0 7.4 7.6 9.7 1.7 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 DUF2502 PF10697.4 EDO18748.1 - 3.7 7.7 11.5 9 6.4 8.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2502) Trypan_PARP PF05887.6 EDO18748.1 - 4 7.2 8.7 6.3 6.6 6.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) A2L_zn_ribbon PF08792.5 EDO18748.1 - 4.4 6.8 9.7 2.2e+02 1.4 6.7 2.9 1 1 0 1 1 1 0 A2L zinc ribbon domain Gag_spuma PF03276.9 EDO18748.1 - 5.7 5.1 12.0 6.7 4.9 8.3 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Ndc1_Nup PF09531.5 EDO18748.1 - 7.8 4.7 10.4 9.2 4.5 7.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Csm1 PF12539.3 EDO18749.1 - 1.9e-33 114.7 1.0 7.8e-33 112.8 0.1 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Lebercilin PF15619.1 EDO18749.1 - 0.002 17.6 2.0 0.002 17.6 1.4 1.7 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease CENP-Q PF13094.1 EDO18749.1 - 0.0066 16.4 3.9 0.031 14.3 0.4 2.1 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Cluap1 PF10234.4 EDO18749.1 - 0.015 14.5 3.5 0.026 13.7 1.1 1.9 2 0 0 2 2 2 0 Clusterin-associated protein-1 COG2 PF06148.6 EDO18749.1 - 0.027 14.3 0.6 0.027 14.3 0.4 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Complex1_49kDa PF00346.14 EDO18749.1 - 0.035 13.1 0.1 0.069 12.1 0.0 1.5 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Herpes_ori_bp PF02399.10 EDO18749.1 - 0.079 10.8 0.1 0.1 10.4 0.0 1.1 1 0 0 1 1 1 0 Origin of replication binding protein NPV_P10 PF05531.7 EDO18749.1 - 0.11 12.7 1.8 0.31 11.3 0.7 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF730 PF05325.6 EDO18749.1 - 0.17 11.6 1.0 0.32 10.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF730) SlyX PF04102.7 EDO18749.1 - 0.65 10.4 2.8 3.1 8.2 0.2 2.8 2 1 1 3 3 2 0 SlyX Kinesin-relat_1 PF12711.2 EDO18749.1 - 0.87 10.0 6.4 0.65 10.4 2.7 2.1 2 0 0 2 2 2 0 Kinesin motor DUF1664 PF07889.7 EDO18749.1 - 1.5 8.6 4.6 3.7 7.3 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.1 EDO18749.1 - 1.6 9.0 7.1 3.7 7.9 3.8 2.3 2 1 0 2 2 2 0 Snapin/Pallidin ATG16 PF08614.6 EDO18749.1 - 2 8.2 9.3 0.16 11.7 3.3 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EDO18749.1 - 5 6.6 5.7 1.6 8.2 1.7 1.7 2 0 0 2 2 2 0 IncA protein WD40 PF00400.27 EDO18750.1 - 5.6e-62 203.5 14.2 3e-10 39.5 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EDO18750.1 - 3e-30 104.2 13.5 3e-30 104.2 9.3 2.2 2 0 0 2 2 2 1 Tup N-terminal Nup160 PF11715.3 EDO18750.1 - 0.00025 19.3 5.0 0.18 9.8 0.2 3.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 CCDC-167 PF15188.1 EDO18750.1 - 4.1 7.4 7.2 10 6.1 5.0 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 GHMP_kinases_N PF00288.21 EDO18751.1 - 1.8e-10 40.7 0.5 4.6e-10 39.4 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain UbiA PF01040.13 EDO18752.1 - 5.3e-32 111.0 15.2 7e-32 110.6 10.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Med12 PF09497.5 EDO18755.1 - 2.1e-24 85.2 0.2 6.2e-24 83.7 0.1 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DEAD PF00270.24 EDO18756.1 - 4.7e-44 149.8 0.2 8.2e-44 149.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO18756.1 - 4.9e-18 64.7 0.5 1.2e-17 63.5 0.4 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO18756.1 - 1.4e-08 34.8 0.2 1.4e-08 34.8 0.1 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EDO18756.1 - 4.6e-08 32.2 0.1 8.2e-08 31.3 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Flavi_DEAD PF07652.9 EDO18756.1 - 8e-05 22.4 0.1 0.037 13.7 0.0 2.7 1 1 1 2 2 2 2 Flavivirus DEAD domain AAA_22 PF13401.1 EDO18756.1 - 0.0022 18.1 1.1 0.01 15.9 0.8 2.1 1 1 0 1 1 1 1 AAA domain Daxx PF03344.10 EDO18756.1 - 4.2 5.7 26.9 8.9 4.6 18.6 1.5 1 0 0 1 1 1 0 Daxx Family UvrD-helicase PF00580.16 EDO18756.1 - 6 6.0 14.2 0.16 11.2 1.3 2.5 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Ribosomal_S19 PF00203.16 EDO18757.1 - 9.8e-21 73.1 0.0 1.2e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 PP2C PF00481.16 EDO18758.1 - 7.7e-31 107.3 0.0 7e-28 97.6 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EDO18758.1 - 0.013 14.8 0.0 0.042 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2C SpoIIE PF07228.7 EDO18758.1 - 0.069 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Ribosom_S12_S23 PF00164.20 EDO18759.1 - 8.1e-43 144.7 0.5 1.3e-42 144.1 0.3 1.3 2 0 0 2 2 2 1 Ribosomal protein S12/S23 PAT1 PF09770.4 EDO18760.1 - 2.8e-244 813.1 77.4 1e-242 807.9 53.7 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 PI31_Prot_C PF08577.6 EDO18761.1 - 3e-11 43.7 10.7 3e-11 43.7 7.4 2.3 2 1 1 3 3 3 1 PI31 proteasome regulator DUF3215 PF11503.3 EDO18762.1 - 2e-35 120.2 0.6 2.2e-35 120.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) Matrilin_ccoil PF10393.4 EDO18763.1 - 0.077 12.3 0.3 0.15 11.4 0.2 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Glucosamine_iso PF01182.15 EDO18764.1 - 5.5e-47 160.0 0.0 8.1e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Chorismate_bind PF00425.13 EDO18765.1 - 6.3e-65 219.0 0.0 1e-64 218.3 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EDO18765.1 - 1.6e-28 99.5 0.0 2.5e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EDO18765.1 - 3.2e-15 56.3 0.0 7.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EDO18765.1 - 5.3e-08 32.5 0.0 9.5e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 Pkinase PF00069.20 EDO18766.1 - 2.8e-62 210.2 0.0 6.1e-62 209.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18766.1 - 4.7e-34 117.6 0.0 5.9e-33 114.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO18766.1 - 3.1e-05 23.0 0.1 0.0015 17.5 0.0 2.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EDO18766.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 EDO18767.1 - 9.6e-86 278.9 33.5 1.2e-14 53.5 0.1 8.5 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EDO18767.1 - 2.4e-08 33.8 4.9 0.00021 21.0 0.0 3.9 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 EDO18767.1 - 2e-07 30.9 0.0 3.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EDO18767.1 - 1.9e-06 26.3 14.9 0.015 13.5 0.1 5.7 3 3 2 5 5 5 2 Nucleoporin Nup120/160 Gmad1 PF10647.4 EDO18767.1 - 0.0006 19.2 0.2 0.22 10.8 0.0 2.3 2 0 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 EDO18767.1 - 0.0031 16.6 1.6 0.61 9.1 0.1 3.1 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EDO18767.1 - 0.014 13.6 0.1 0.79 7.9 0.0 3.0 3 1 1 4 4 4 0 Cytochrome D1 heme domain Apc4_WD40 PF12894.2 EDO18767.1 - 0.017 14.6 0.0 0.12 11.8 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.7 EDO18767.1 - 0.053 13.1 0.0 19 5.0 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 EDO18767.1 - 0.1 10.7 0.0 0.73 7.9 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) TFIIIC_delta PF12657.2 EDO18767.1 - 0.59 9.8 5.4 10 5.7 0.1 3.8 2 2 2 4 4 4 0 Transcription factor IIIC subunit delta N-term Glyco_transf_22 PF03901.12 EDO18768.1 - 2.4e-26 92.7 24.6 3.3e-26 92.2 17.0 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pro_isomerase PF00160.16 EDO18769.1 - 9.9e-29 100.5 0.1 1.8e-28 99.7 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lipase_3 PF01764.20 EDO18770.1 - 1.5e-08 34.3 0.0 2.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 EDO18770.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 EDO18770.1 - 0.019 14.6 0.0 0.051 13.3 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO18770.1 - 0.073 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Phos_pyr_kin PF08543.7 EDO18771.1 - 5.2e-09 35.6 0.0 8.3e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EDO18771.1 - 0.00069 18.8 0.0 0.022 13.8 0.0 2.2 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Fork_head PF00250.13 EDO18772.1 - 2.7e-36 123.4 1.0 1.5e-35 121.1 0.2 2.3 2 0 0 2 2 2 1 Fork head domain G10 PF01125.12 EDO18773.1 - 2.8e-59 198.8 11.8 3.2e-59 198.6 8.2 1.0 1 0 0 1 1 1 1 G10 protein MAGE PF01454.14 EDO18773.1 - 0.13 11.5 2.5 0.16 11.2 1.3 1.4 1 1 1 2 2 2 0 MAGE family DUF947 PF06102.7 EDO18773.1 - 1.5 8.6 9.2 2.1 8.1 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF947) ANTH PF07651.11 EDO18774.1 - 6.6e-59 198.9 0.2 6.6e-59 198.9 0.1 1.9 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 EDO18774.1 - 0.00089 19.1 3.0 0.0031 17.3 0.1 2.5 2 0 0 2 2 2 1 ENTH domain GAS PF13851.1 EDO18774.1 - 0.0034 16.6 6.9 0.0059 15.8 4.8 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FliJ PF02050.11 EDO18774.1 - 0.0081 16.2 8.8 0.0081 16.2 6.1 2.1 2 0 0 2 2 2 1 Flagellar FliJ protein IncA PF04156.9 EDO18774.1 - 0.028 14.0 9.0 0.052 13.1 6.3 1.4 1 0 0 1 1 1 0 IncA protein eIF3_subunit PF08597.5 EDO18774.1 - 0.051 13.1 2.9 0.093 12.2 2.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CheD PF03975.8 EDO18774.1 - 0.1 12.3 15.4 3.1 7.5 0.3 4.8 1 1 5 6 6 6 0 CheD chemotactic sensory transduction TMF_DNA_bd PF12329.3 EDO18774.1 - 0.11 12.3 7.0 0.24 11.2 4.9 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SPT16 PF08644.6 EDO18774.1 - 0.24 11.2 2.4 0.46 10.3 1.7 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF1940 PF09155.5 EDO18774.1 - 0.26 11.1 1.5 0.56 10.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1940) DUF3552 PF12072.3 EDO18774.1 - 6.3 5.9 8.5 11 5.2 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) PH PF00169.24 EDO18775.1 - 2.3e-06 27.7 1.5 2.3e-06 27.7 1.0 2.7 3 0 0 3 3 3 1 PH domain DUF3287 PF11690.3 EDO18775.1 - 0.074 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) TPR_11 PF13414.1 EDO18776.1 - 9.8e-16 57.1 0.3 7e-15 54.4 0.0 1.9 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.23 EDO18776.1 - 1.5e-10 40.2 0.2 9.2e-08 31.3 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EDO18776.1 - 2.3e-10 39.5 0.0 1.9e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO18776.1 - 2.9e-06 26.6 4.8 0.0001 21.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EDO18776.1 - 1.9e-05 24.6 0.6 4.1e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EDO18776.1 - 2.3e-05 23.8 0.1 0.001 18.7 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO18776.1 - 6.5e-05 22.8 0.5 0.0078 16.1 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EDO18776.1 - 6.6e-05 22.7 0.4 0.0074 16.1 0.1 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 EDO18776.1 - 0.00011 22.4 0.0 0.00024 21.3 0.0 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO18776.1 - 0.0004 20.9 0.0 0.035 14.8 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EDO18776.1 - 0.00046 20.1 1.0 0.022 14.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO18776.1 - 0.00046 20.4 0.3 0.29 11.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3856 PF12968.2 EDO18776.1 - 0.014 15.2 0.0 0.16 11.7 0.0 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) Toprim_N PF08275.6 EDO18776.1 - 0.031 14.2 0.4 0.062 13.2 0.3 1.7 1 1 0 1 1 1 0 DNA primase catalytic core, N-terminal domain MIT PF04212.13 EDO18776.1 - 0.037 13.9 2.0 0.9 9.4 0.1 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain UPF0029 PF01205.14 EDO18777.1 - 4.7e-31 106.7 0.0 6.8e-31 106.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EDO18777.1 - 2.2e-10 40.4 0.6 4.4e-10 39.4 0.4 1.5 1 0 0 1 1 1 1 RWD domain DUF4119 PF13494.1 EDO18777.1 - 0.097 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) WD40 PF00400.27 EDO18779.1 - 5e-60 197.3 17.3 3.5e-13 48.8 0.1 12.8 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 EDO18779.1 - 5.2e-29 100.3 0.1 8.2e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nbas_N PF15492.1 EDO18779.1 - 6.2e-05 22.2 0.5 0.49 9.4 0.0 4.2 3 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EDO18779.1 - 0.00066 19.2 0.4 0.14 11.5 0.1 3.6 1 1 2 3 3 3 1 PQQ-like domain SGL PF08450.7 EDO18779.1 - 0.0027 17.1 0.2 6.9 5.9 0.0 4.3 4 2 1 5 5 5 1 SMP-30/Gluconolaconase/LRE-like region CPSF_A PF03178.10 EDO18779.1 - 0.018 14.1 0.3 1.3 8.0 0.0 3.2 2 1 1 4 4 4 0 CPSF A subunit region Apc4_WD40 PF12894.2 EDO18779.1 - 0.035 13.6 0.0 24 4.5 0.0 4.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Utp13 PF08625.6 EDO18779.1 - 0.1 12.2 0.1 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain Proteasome_A_N PF10584.4 EDO18779.1 - 0.15 11.4 1.3 2.1 7.7 0.1 3.0 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature NOA36 PF06524.7 EDO18779.1 - 1.9 7.6 3.1 3.7 6.7 2.2 1.4 1 0 0 1 1 1 0 NOA36 protein Atx10homo_assoc PF09759.4 EDO18780.1 - 2.2e-39 133.2 3.2 4.5e-39 132.3 1.0 2.3 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain B-block_TFIIIC PF04182.7 EDO18781.1 - 0.017 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Gal4_dimer PF03902.8 EDO18782.1 - 0.029 14.2 0.3 0.056 13.3 0.2 1.4 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF1836 PF08876.6 EDO18782.1 - 0.17 11.6 1.1 1.2 8.9 0.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1836) Ank_5 PF13857.1 EDO18783.1 - 1.8e-17 62.9 0.1 1.4e-12 47.4 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO18783.1 - 4.1e-11 43.0 0.0 8.1e-11 42.1 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDO18783.1 - 1.5e-10 41.3 0.2 3.1e-06 27.5 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO18783.1 - 2.1e-08 33.5 0.1 0.00041 20.3 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.25 EDO18783.1 - 6.5e-08 32.0 0.2 3.4e-05 23.4 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ribosomal_L19 PF01245.15 EDO18784.1 - 1.3e-11 44.2 0.1 2.2e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 SH3_2 PF07653.12 EDO18784.1 - 0.09 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain HIG_1_N PF04588.8 EDO18785.1 - 5.3e-05 22.8 0.2 9.7e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Asp-Al_Ex PF06826.7 EDO18785.1 - 0.082 12.3 0.0 0.2 11.1 0.0 1.5 2 0 0 2 2 2 0 Predicted Permease Membrane Region Peptidase_S8 PF00082.17 EDO18786.1 - 6e-47 160.1 1.9 1e-46 159.3 1.3 1.3 1 0 0 1 1 1 1 Subtilase family CDC45 PF02724.9 EDO18786.1 - 0.001 17.1 3.6 0.0014 16.7 2.5 1.2 1 0 0 1 1 1 1 CDC45-like protein Inhibitor_I9 PF05922.11 EDO18786.1 - 0.03 14.8 0.0 0.087 13.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I9 Mak16 PF04874.9 EDO18786.1 - 0.043 13.8 13.9 0.022 14.8 6.6 2.2 2 0 0 2 2 2 0 Mak16 protein C-terminal region Nop14 PF04147.7 EDO18786.1 - 0.22 9.3 12.9 0.38 8.6 8.9 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EDO18786.1 - 0.28 9.6 9.2 0.43 9.0 6.4 1.2 1 0 0 1 1 1 0 Daxx Family Prothymosin PF03247.9 EDO18786.1 - 0.31 11.2 26.3 1.6 8.9 16.0 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family CobT PF06213.7 EDO18786.1 - 1 8.4 12.6 2.5 7.1 8.7 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2722 PF10846.3 EDO18786.1 - 3.1 6.7 4.2 4.5 6.2 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) G-patch PF01585.18 EDO18787.1 - 3.4e-10 39.5 0.1 1.1e-09 37.9 0.1 1.9 1 0 0 1 1 1 1 G-patch domain SprA-related PF12118.3 EDO18787.1 - 0.0029 16.9 18.9 0.0036 16.6 13.1 1.2 1 0 0 1 1 1 1 SprA-related family MIP-T3 PF10243.4 EDO18787.1 - 0.11 10.9 52.5 0.15 10.5 36.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2201_N PF13203.1 EDO18787.1 - 0.89 8.6 17.3 1.1 8.3 12.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain PLRV_ORF5 PF01690.12 EDO18787.1 - 1.1 8.3 25.2 1.4 7.9 17.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Hid1 PF12722.2 EDO18787.1 - 2.9 5.4 26.3 3.7 5.1 18.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 EDO18787.1 - 4.2 4.9 28.6 5.3 4.6 19.8 1.2 1 0 0 1 1 1 0 Ycf1 DUF913 PF06025.7 EDO18787.1 - 7.1 5.2 11.8 10 4.7 8.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Glyco_hydro_72 PF03198.9 EDO18788.1 - 3.7e-143 476.1 11.4 6.4e-143 475.4 7.9 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EDO18788.1 - 2.5e-27 95.1 7.3 1.1e-26 93.0 5.1 2.3 1 0 0 1 1 1 1 X8 domain Glyco_hydro_2_C PF02836.12 EDO18788.1 - 7.8e-06 25.0 0.5 1.2e-05 24.3 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ribosomal_L7Ae PF01248.21 EDO18788.1 - 0.11 12.0 0.1 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pex14_N PF04695.8 EDO18788.1 - 0.82 9.7 11.3 0.092 12.7 4.4 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TraG-D_C PF12696.2 EDO18788.1 - 4.2 7.2 7.2 17 5.2 4.4 2.3 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Glucan_synthase PF02364.10 EDO18789.1 - 0 1353.7 13.3 0 1353.7 9.2 2.1 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EDO18789.1 - 3.3e-39 133.4 0.7 3.3e-39 133.4 0.5 2.3 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_17 PF00332.13 EDO18791.1 - 7.4e-08 31.7 0.5 7.4e-08 31.7 0.4 2.1 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 TFIIA PF03153.8 EDO18791.1 - 0.17 11.7 15.2 0.35 10.7 10.5 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EDO18791.1 - 0.47 8.6 10.1 0.58 8.3 7.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DNA_pol_viral_N PF00242.12 EDO18791.1 - 8 5.3 7.5 10 5.0 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain MA3 PF02847.12 EDO18792.1 - 2e-18 66.1 0.4 5.8e-17 61.4 0.0 2.7 2 1 1 3 3 3 1 MA3 domain MIF4G PF02854.14 EDO18792.1 - 1.8e-10 40.5 6.0 1.8e-10 40.5 4.1 2.8 2 1 0 2 2 2 1 MIF4G domain APG6 PF04111.7 EDO18792.1 - 0.0037 16.3 2.1 0.0076 15.3 1.4 1.5 1 0 0 1 1 1 1 Autophagy protein Apg6 NAD_binding_4 PF07993.7 EDO18792.1 - 0.088 11.7 0.0 0.21 10.4 0.0 1.6 1 0 0 1 1 1 0 Male sterility protein CTP_transf_2 PF01467.21 EDO18793.1 - 7.5e-15 55.3 0.0 1.1e-14 54.8 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase GATase_2 PF00310.16 EDO18794.1 - 1.5e-23 83.1 0.2 4.6e-18 65.0 0.0 2.9 1 1 2 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EDO18794.1 - 6e-16 58.6 0.0 1.9e-15 56.9 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EDO18794.1 - 6.8e-13 48.4 0.0 1.8e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EDO18794.1 - 2e-10 40.4 0.0 3.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EDO18794.1 - 3.6e-06 25.8 0.0 6.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II KH_5 PF13184.1 EDO18794.1 - 0.096 12.4 0.2 13 5.6 0.0 2.4 2 0 0 2 2 2 0 NusA-like KH domain Rtt102p PF09510.5 EDO18795.1 - 1.3e-49 167.4 0.9 1.3e-49 167.4 0.6 2.1 2 0 0 2 2 2 1 Rtt102p-like transcription regulator protein DUF3367 PF11847.3 EDO18795.1 - 0.33 8.8 4.7 0.41 8.5 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) OPT PF03169.10 EDO18796.1 - 0.01 14.2 0.1 0.013 14.0 0.1 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Peptidase_S10 PF00450.17 EDO18797.1 - 1.1e-128 430.0 4.5 1.3e-128 429.7 3.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EDO18797.1 - 0.00079 19.5 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EDO18797.1 - 0.032 14.1 0.0 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2406 PF10295.4 EDO18798.1 - 1.3e-27 96.0 0.2 2.3e-27 95.2 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) TcdB_toxin_midC PF12255.3 EDO18798.1 - 0.0056 16.3 0.5 0.012 15.2 0.4 1.4 1 1 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region Sec63 PF02889.11 EDO18799.1 - 2.1e-141 470.6 1.4 3.2e-92 309.1 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EDO18799.1 - 9.7e-54 181.3 2.3 2.4e-28 98.7 0.7 4.0 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 EDO18799.1 - 2e-21 76.6 0.0 9.5e-11 41.8 0.2 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EDO18799.1 - 9.7e-19 67.0 0.0 2.1e-08 33.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDO18799.1 - 3.5e-08 32.6 0.2 0.001 17.9 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA_22 PF13401.1 EDO18799.1 - 2.2e-06 27.8 5.9 0.032 14.3 0.1 4.7 4 1 0 4 4 4 2 AAA domain AAA PF00004.24 EDO18799.1 - 3.6e-06 27.2 1.4 0.17 12.1 0.0 4.4 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EDO18799.1 - 1.6e-05 24.2 0.1 0.019 14.1 0.0 3.0 3 0 0 3 3 3 2 PhoH-like protein IstB_IS21 PF01695.12 EDO18799.1 - 0.00062 19.2 0.2 1.2 8.4 0.0 4.0 5 0 0 5 5 5 1 IstB-like ATP binding protein AAA_18 PF13238.1 EDO18799.1 - 0.0086 16.3 1.9 6.1 7.1 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 EDO18799.1 - 0.032 13.6 3.0 37 3.6 0.0 4.3 2 2 0 4 4 4 0 AAA-like domain NAC PF01849.13 EDO18800.1 - 4.1e-21 74.2 1.4 5.5e-21 73.8 0.3 1.8 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EDO18800.1 - 4.8e-05 23.0 0.2 9.6e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain LPP PF04728.8 EDO18800.1 - 0.027 14.2 1.5 0.069 12.9 1.0 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper UBA_4 PF14555.1 EDO18800.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain HrpB7 PF09486.5 EDO18800.1 - 0.29 11.0 4.9 0.18 11.7 1.5 1.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) TMF_DNA_bd PF12329.3 EDO18800.1 - 0.89 9.4 9.5 8.3 6.3 0.2 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF2296 PF10058.4 EDO18801.1 - 2.6e-15 55.9 0.2 4.4e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Zn_Tnp_IS1595 PF12760.2 EDO18801.1 - 0.0032 17.2 1.1 0.0068 16.1 0.7 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 EDO18801.1 - 0.028 14.7 5.1 0.69 10.3 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 EDO18801.1 - 0.041 14.2 2.9 10 6.7 0.2 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type O-antigen_lig PF13425.1 EDO18801.1 - 0.049 13.6 0.1 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein zinc_ribbon_5 PF13719.1 EDO18801.1 - 0.052 13.1 2.0 0.25 10.9 1.4 2.0 1 1 0 1 1 1 0 zinc-ribbon domain DUF3037 PF11236.3 EDO18801.1 - 0.056 13.4 0.3 0.11 12.5 0.1 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF3037) Rubredoxin PF00301.15 EDO18801.1 - 0.06 13.2 2.1 0.54 10.1 0.2 2.6 2 0 0 2 2 2 0 Rubredoxin zinc_ribbon_4 PF13717.1 EDO18801.1 - 0.061 13.0 2.3 0.29 10.8 1.6 2.0 1 1 0 1 1 1 0 zinc-ribbon domain DUF2368 PF10166.4 EDO18801.1 - 0.065 12.8 0.8 0.091 12.3 0.0 1.6 2 0 0 2 2 1 0 Uncharacterised conserved protein (DUF2368) Zn-ribbon_8 PF09723.5 EDO18801.1 - 0.067 13.1 3.3 2.6 8.0 2.7 2.4 1 1 2 3 3 3 0 Zinc ribbon domain Desulfoferrod_N PF06397.7 EDO18801.1 - 0.078 12.3 0.2 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zf-ISL3 PF14690.1 EDO18801.1 - 0.08 12.9 0.7 6.7 6.8 0.0 2.6 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-ribbon_3 PF13248.1 EDO18801.1 - 0.086 12.0 2.7 1.6 8.0 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 EDO18801.1 - 0.11 12.1 1.9 0.52 10.0 0.1 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS FYVE PF01363.16 EDO18801.1 - 0.12 12.2 0.1 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-HIT PF04438.11 EDO18801.1 - 0.16 11.6 2.9 0.87 9.2 0.3 2.2 2 0 0 2 2 2 0 HIT zinc finger GvpK PF05121.7 EDO18801.1 - 0.19 11.5 3.2 0.79 9.5 0.0 2.6 2 1 0 2 2 2 0 Gas vesicle protein K NBP1 PF08537.5 EDO18801.1 - 0.52 9.4 8.3 1.4 8.0 4.6 1.9 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 ATG16 PF08614.6 EDO18801.1 - 0.65 9.7 12.9 1.5 8.6 6.7 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EDO18801.1 - 0.85 9.1 7.1 1.8 8.1 2.7 2.2 2 0 0 2 2 2 0 IncA protein zinc_ribbon_2 PF13240.1 EDO18801.1 - 1.3 8.5 6.5 0.99 8.9 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DUF4446 PF14584.1 EDO18801.1 - 1.6 8.5 8.4 4.2 7.1 2.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) TF_Zn_Ribbon PF08271.7 EDO18801.1 - 6 6.2 9.5 2 7.8 3.5 2.5 2 1 0 2 2 2 0 TFIIB zinc-binding zf-Mss51 PF13824.1 EDO18801.1 - 7.3 6.5 7.0 1.4 8.8 0.7 2.8 4 0 0 4 4 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Ctf8 PF09696.5 EDO18802.1 - 1.7e-28 98.8 0.0 2.5e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Ctf8 Glyco_hydro_47 PF01532.15 EDO18803.1 - 2.9e-139 464.6 0.6 3.3e-139 464.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cys_Met_Meta_PP PF01053.15 EDO18804.1 - 4.6e-27 94.2 0.0 1.5e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EDO18804.1 - 1e-05 24.6 0.0 1.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_16 PF10294.4 EDO18805.1 - 3.3e-22 78.7 0.3 6e-22 77.9 0.2 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EDO18805.1 - 0.001 18.4 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EDO18805.1 - 0.0047 17.4 0.0 0.0086 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO18805.1 - 0.026 14.9 0.1 0.056 13.9 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EDO18805.1 - 0.047 12.8 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EDO18805.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Zn_clus PF00172.13 EDO18806.1 - 4.1e-07 29.8 10.9 9.5e-07 28.6 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RepA_N PF06970.6 EDO18806.1 - 0.041 13.6 0.1 0.041 13.6 0.1 2.7 2 1 1 3 3 3 0 Replication initiator protein A (RepA) N-terminus Septin PF00735.13 EDO18807.1 - 9.5e-107 356.1 0.7 1.1e-106 355.9 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EDO18807.1 - 1.6e-08 34.5 0.1 2.5e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDO18807.1 - 3.6e-08 33.0 0.6 1.1e-06 28.1 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EDO18807.1 - 5e-07 29.0 0.1 9.3e-07 28.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDO18807.1 - 8.1e-06 25.7 0.4 0.016 15.0 0.2 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 EDO18807.1 - 1.1e-05 24.6 0.2 2.8e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 AIG1 family AAA_24 PF13479.1 EDO18807.1 - 0.00055 19.5 0.1 0.0012 18.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EDO18807.1 - 0.00061 20.1 0.4 0.0014 18.9 0.1 1.7 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 EDO18807.1 - 0.0019 17.6 0.1 0.0034 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EDO18807.1 - 0.0024 17.8 0.1 0.0038 17.2 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EDO18807.1 - 0.0025 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 EDO18807.1 - 0.0042 17.5 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein NB-ARC PF00931.17 EDO18807.1 - 0.0052 15.6 0.1 0.01 14.7 0.1 1.4 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EDO18807.1 - 0.011 15.9 0.0 0.046 13.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EDO18807.1 - 0.03 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EDO18807.1 - 0.03 13.2 0.1 0.047 12.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EDO18807.1 - 0.031 14.1 0.4 0.087 12.6 0.2 1.9 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EDO18807.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EDO18807.1 - 0.038 13.4 0.1 0.83 9.1 0.1 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.7 EDO18807.1 - 0.046 12.9 0.3 0.18 11.0 0.1 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein IIGP PF05049.8 EDO18807.1 - 0.048 12.4 0.2 0.16 10.7 0.1 1.7 1 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MacB_PCD PF12704.2 EDO18807.1 - 0.053 13.0 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 MacB-like periplasmic core domain MobB PF03205.9 EDO18807.1 - 0.089 12.4 0.2 0.31 10.7 0.1 2.0 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EDO18807.1 - 0.11 13.3 0.2 0.22 12.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain Flavodoxin_1 PF00258.20 EDO18808.1 - 6e-08 32.8 0.1 2e-07 31.1 0.0 2.0 2 2 0 2 2 2 1 Flavodoxin FMN_red PF03358.10 EDO18808.1 - 5.9e-07 29.1 0.0 2.2e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.2 EDO18808.1 - 0.019 14.9 0.0 0.21 11.5 0.0 2.2 1 1 1 2 2 2 0 Flavodoxin domain Bacteriocin_IIc PF10439.4 EDO18808.1 - 0.19 11.8 3.9 0.42 10.7 0.7 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide ATP_synt_H PF05493.8 EDO18810.1 - 4.7e-23 81.0 7.6 5.2e-23 80.8 5.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Git3 PF11710.3 EDO18810.1 - 0.0062 16.1 1.0 0.0069 15.9 0.7 1.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 YfhO PF09586.5 EDO18810.1 - 0.032 12.2 2.0 0.034 12.1 1.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO 7TM-7TMR_HD PF07698.6 EDO18810.1 - 0.046 13.1 2.8 0.052 12.9 1.9 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase DUF2909 PF11137.3 EDO18810.1 - 0.067 12.9 2.6 0.18 11.5 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2909) MgtE PF01769.11 EDO18810.1 - 0.069 13.4 1.3 0.066 13.5 0.9 1.0 1 0 0 1 1 1 0 Divalent cation transporter YibE_F PF07907.6 EDO18810.1 - 0.079 12.1 0.5 0.082 12.0 0.3 1.0 1 0 0 1 1 1 0 YibE/F-like protein DUF4131 PF13567.1 EDO18810.1 - 0.13 11.6 2.5 0.13 11.6 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3624 PF12292.3 EDO18810.1 - 0.16 12.3 3.4 0.25 11.7 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3624) Oxidored_q4 PF00507.14 EDO18810.1 - 0.36 10.6 4.4 0.43 10.4 3.0 1.0 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF21 PF01595.15 EDO18810.1 - 0.38 10.0 3.5 0.4 9.9 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF21 TMEM192 PF14802.1 EDO18810.1 - 0.41 9.4 2.1 0.4 9.4 1.4 1.0 1 0 0 1 1 1 0 TMEM192 family AA_permease_2 PF13520.1 EDO18810.1 - 0.82 8.1 6.8 0.9 8.0 4.7 1.0 1 0 0 1 1 1 0 Amino acid permease Lipase_3 PF01764.20 EDO18811.1 - 2.3e-38 131.0 0.0 3.9e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EDO18811.1 - 0.00057 19.3 0.0 0.18 11.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Esterase PF00756.15 EDO18811.1 - 0.0031 16.9 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EDO18811.1 - 0.0083 15.8 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO18811.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Nnf1 PF03980.9 EDO18812.1 - 4e-31 107.2 7.6 6.6e-31 106.5 5.3 1.4 1 0 0 1 1 1 1 Nnf1 DUF1664 PF07889.7 EDO18812.1 - 0.0081 15.9 2.1 0.12 12.1 0.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Prefoldin PF02996.12 EDO18812.1 - 0.015 14.9 5.2 0.052 13.2 1.3 2.6 2 1 0 2 2 2 0 Prefoldin subunit DASH_Spc34 PF08657.5 EDO18812.1 - 0.018 14.7 1.4 0.018 14.7 1.0 1.8 2 0 0 2 2 2 0 DASH complex subunit Spc34 DUF4298 PF14131.1 EDO18812.1 - 0.033 14.0 0.8 0.09 12.6 0.1 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) Peptidase_C93 PF06035.6 EDO18812.1 - 0.062 12.7 1.6 0.16 11.3 0.1 2.2 1 1 1 2 2 2 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Hrs_helical PF12210.3 EDO18812.1 - 0.071 13.3 1.2 0.071 13.3 0.8 1.9 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Flu_NS2 PF00601.14 EDO18812.1 - 0.071 13.3 5.4 0.4 10.9 0.7 2.4 1 1 1 2 2 2 0 Influenza non-structural protein (NS2) DUF3373 PF11853.3 EDO18812.1 - 0.18 10.3 0.2 0.26 9.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) CENP-Q PF13094.1 EDO18812.1 - 0.2 11.7 6.9 0.23 11.4 2.9 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit APP_E2 PF12925.2 EDO18812.1 - 0.49 9.9 4.7 0.11 12.0 0.5 1.9 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein bZIP_2 PF07716.10 EDO18812.1 - 0.66 9.8 4.6 2 8.3 3.2 1.8 1 0 0 1 1 1 0 Basic region leucine zipper YlqD PF11068.3 EDO18812.1 - 1 9.4 8.7 2 8.4 5.3 2.0 1 1 1 2 2 2 0 YlqD protein Snapin_Pallidin PF14712.1 EDO18812.1 - 2.4 8.4 7.4 0.94 9.8 0.7 2.5 2 1 0 2 2 2 0 Snapin/Pallidin DUF4404 PF14357.1 EDO18812.1 - 3.3 8.1 9.2 0.6 10.5 3.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) AAA_23 PF13476.1 EDO18812.1 - 4.7 7.4 9.0 7.2 6.8 6.3 1.3 1 0 0 1 1 1 0 AAA domain TcdB_N PF12918.2 EDO18812.1 - 5.2 7.2 7.4 1.9 8.6 1.8 2.5 2 1 0 2 2 2 0 TcdB toxin N-terminal helical domain SlyX PF04102.7 EDO18812.1 - 5.9 7.3 13.1 6.3 7.2 3.1 3.3 2 1 1 3 3 3 0 SlyX Cauli_AT PF03233.8 EDO18812.1 - 7.1 6.3 7.5 4.4 6.9 1.2 2.2 1 1 1 2 2 2 0 Aphid transmission protein EF-hand_4 PF12763.2 EDO18813.1 - 1.6e-23 82.3 2.6 1e-10 41.2 0.0 3.2 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 EDO18813.1 - 4.6e-10 39.0 0.1 1.5e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 EDO18813.1 - 3.8e-06 25.7 0.9 0.0046 16.1 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EDO18813.1 - 4e-05 23.6 3.9 0.00018 21.5 0.0 3.8 3 1 1 4 4 4 2 EF-hand domain pair UBA_4 PF14555.1 EDO18813.1 - 0.00011 21.7 0.3 0.00011 21.7 0.2 1.9 2 0 0 2 2 2 1 UBA-like domain EF-hand_6 PF13405.1 EDO18813.1 - 0.00032 20.3 0.1 0.27 11.2 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain IncA PF04156.9 EDO18813.1 - 1.6 8.3 45.7 0.063 12.8 6.5 3.6 2 1 2 4 4 4 0 IncA protein MbeD_MobD PF04899.7 EDO18813.1 - 3 7.8 10.6 0.34 10.8 1.7 2.9 2 0 0 2 2 2 0 MbeD/MobD like ERM PF00769.14 EDO18813.1 - 7.6 5.9 40.7 0.18 11.2 10.8 2.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Peptidase_M20 PF01546.23 EDO18815.1 - 1.9e-22 79.6 0.0 3e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EDO18815.1 - 1.1e-12 47.6 0.0 2.5e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Beta_elim_lyase PF01212.16 EDO18815.1 - 0.041 13.0 0.1 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Proteasome PF00227.21 EDO18816.1 - 1.5e-35 122.2 0.0 8.4e-35 119.7 0.0 1.8 1 1 0 1 1 1 1 Proteasome subunit ER_lumen_recept PF00810.13 EDO18817.1 - 8.8e-49 165.7 14.7 1.4e-48 165.1 10.2 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor Sod_Cu PF00080.15 EDO18819.1 - 5.2e-43 146.6 3.5 6.2e-43 146.3 2.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CTP_synth_N PF06418.9 EDO18820.1 - 9.5e-120 398.8 0.8 1.3e-119 398.3 0.5 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EDO18820.1 - 1.4e-57 194.2 0.0 2.2e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDO18820.1 - 0.00017 21.0 0.0 0.00086 18.8 0.0 2.1 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.18 EDO18820.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Tweety PF04906.8 EDO18821.1 - 0.042 12.2 1.6 0.066 11.6 1.1 1.3 1 0 0 1 1 1 0 Tweety DUF2959 PF11172.3 EDO18821.1 - 0.096 12.4 4.6 0.1 12.3 2.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Tom22 PF04281.8 EDO18821.1 - 0.84 9.1 4.9 0.33 10.4 1.2 1.9 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 Nup54 PF13874.1 EDO18821.1 - 1.4 8.5 8.6 0.19 11.4 0.9 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 ARL2_Bind_BART PF11527.3 EDO18821.1 - 6.1 6.6 8.0 2.8 7.7 2.2 2.4 1 1 0 2 2 2 0 The ARF-like 2 binding protein BART ESCRT-II PF05871.7 EDO18822.1 - 1.7e-44 151.1 1.6 2e-44 150.8 1.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Sod_Fe_C PF02777.13 EDO18823.1 - 2.3e-11 43.4 0.4 2.7e-05 23.9 0.2 2.2 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Peptidase_C12 PF01088.16 EDO18824.1 - 6.6e-49 165.9 0.0 7.3e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PX PF00787.19 EDO18825.1 - 1.2e-08 34.7 0.8 3.3e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 PX domain Ribosomal_L37ae PF01780.14 EDO18826.1 - 1e-38 131.0 10.1 1.1e-38 130.9 7.0 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family CarbpepA_inh PF02977.10 EDO18826.1 - 0.0021 17.5 4.1 0.0037 16.8 0.8 2.1 1 1 1 2 2 2 1 Carboxypeptidase A inhibitor DUF1364 PF07102.7 EDO18826.1 - 0.011 15.6 1.1 0.014 15.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Zn_Tnp_IS1595 PF12760.2 EDO18826.1 - 0.014 15.1 2.6 0.022 14.5 1.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Rep_fac-A_C PF08646.5 EDO18826.1 - 0.019 14.6 0.3 0.022 14.4 0.2 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain zf-H2C2_2 PF13465.1 EDO18826.1 - 0.057 13.7 0.5 0.89 9.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-ribbon_3 PF13248.1 EDO18826.1 - 0.17 11.1 1.0 6.1 6.1 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 EDO18826.1 - 0.2 11.4 1.6 0.3 10.8 1.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.11 EDO18826.1 - 0.22 11.6 2.8 7.2 6.8 0.1 2.3 2 0 0 2 2 2 0 C1 domain zf-BED PF02892.10 EDO18826.1 - 0.29 10.9 4.5 5.5 6.8 0.2 2.3 1 1 1 2 2 2 0 BED zinc finger OrfB_Zn_ribbon PF07282.6 EDO18826.1 - 0.32 10.6 2.2 0.52 10.0 1.4 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Elf1 PF05129.8 EDO18826.1 - 0.32 10.7 2.5 0.81 9.4 1.8 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C4_ClpX PF06689.8 EDO18826.1 - 1.4 8.4 4.7 3.1 7.3 3.3 1.7 1 1 0 1 1 1 0 ClpX C4-type zinc finger MBF1 PF08523.5 EDO18827.1 - 4.2e-25 87.5 1.5 4.2e-25 87.5 1.1 1.8 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EDO18827.1 - 3.1e-14 52.5 0.3 5.3e-14 51.7 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EDO18827.1 - 1.1e-05 25.3 0.2 1.7e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EDO18827.1 - 3.4e-05 23.9 0.0 6.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MitMem_reg PF13012.1 EDO18827.1 - 0.025 14.6 0.2 0.17 12.0 0.0 1.9 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Cauli_VI PF01693.11 EDO18828.1 - 5.5e-26 90.3 2.4 6e-18 64.6 0.7 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EDO18828.1 - 9.1e-26 90.7 0.6 1.7e-25 89.8 0.4 1.5 1 0 0 1 1 1 1 RNase H SWIB PF02201.13 EDO18829.1 - 7.1e-28 96.1 0.2 1.5e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EDO18829.1 - 1.6e-09 37.3 0.3 3.9e-08 32.9 0.1 2.9 2 0 0 2 2 2 1 DEK C terminal domain RRS1 PF04939.7 EDO18830.1 - 3.2e-65 218.6 1.3 3.7e-65 218.4 0.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) S10_plectin PF03501.10 EDO18831.1 - 1.3e-42 143.5 0.6 1.5e-42 143.3 0.4 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF505 PF04458.7 EDO18831.1 - 0.0079 14.3 0.2 0.0091 14.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF505) tRNA-synt_1c_C PF03950.13 EDO18831.1 - 0.019 14.6 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain PadR PF03551.9 EDO18831.1 - 0.034 13.8 0.2 0.034 13.8 0.1 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family YjcQ PF09639.5 EDO18831.1 - 0.047 13.7 0.2 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 YjcQ protein ADH_zinc_N PF00107.21 EDO18832.1 - 8.4e-17 60.9 0.0 1.4e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EDO18832.1 - 0.066 14.1 0.0 0.14 13.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CRC_subunit PF08624.5 EDO18833.1 - 3.9e-35 120.7 0.0 7.5e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Lectin_leg-like PF03388.8 EDO18834.1 - 6.3e-49 166.1 0.0 8.9e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Tropomyosin_1 PF12718.2 EDO18834.1 - 0.08 12.7 4.2 0.12 12.2 2.9 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF4559 PF15112.1 EDO18834.1 - 0.86 8.7 5.7 4.4 6.3 3.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) FCH PF00611.18 EDO18836.1 - 6.6e-17 61.4 0.3 2e-15 56.7 0.0 3.2 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EDO18836.1 - 9.1e-11 41.3 0.1 2.8e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 EDO18836.1 - 2e-09 37.2 0.5 2e-09 37.2 0.3 3.2 2 2 0 2 2 2 1 RhoGAP domain V-SNARE_C PF12352.3 EDO18838.1 - 1.7e-06 28.0 4.7 1.7e-06 28.0 3.3 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EDO18838.1 - 2.2e-05 24.0 0.5 2.2e-05 24.0 0.4 2.1 3 0 0 3 3 3 1 Sec20 Cir_Bir_Yir PF06022.6 EDO18838.1 - 0.0087 15.3 2.2 0.0087 15.3 1.5 1.6 2 0 0 2 2 2 1 Plasmodium variant antigen protein Cir/Yir/Bir DUF3452 PF11934.3 EDO18838.1 - 0.034 13.4 1.4 0.065 12.5 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DinB PF05163.7 EDO18838.1 - 0.043 13.5 0.3 0.099 12.3 0.2 1.6 1 0 0 1 1 1 0 DinB family Hemerythrin PF01814.18 EDO18838.1 - 0.075 13.1 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF4407 PF14362.1 EDO18838.1 - 0.077 11.9 3.9 0.14 11.1 2.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF342 PF03961.8 EDO18838.1 - 0.81 8.0 7.8 3.7 5.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF1151 PF06625.6 EDO18838.1 - 2.1 8.0 6.9 0.98 9.1 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1151) TPR_MLP1_2 PF07926.7 EDO18838.1 - 2.6 7.7 12.8 5.9 6.6 3.0 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF573 PF04504.9 EDO18838.1 - 3.6 7.9 7.3 0.9 9.8 1.0 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF573 GrpE PF01025.14 EDO18838.1 - 6.2 6.3 9.2 2.3 7.7 1.2 2.8 2 1 1 3 3 3 0 GrpE DUF4298 PF14131.1 EDO18838.1 - 9.3 6.2 7.1 30 4.5 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4298) RCC1 PF00415.13 EDO18839.1 - 4.5e-20 71.6 0.9 1.4e-05 25.1 0.0 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDO18839.1 - 9.7e-12 44.1 14.8 1.8e-08 33.7 0.2 5.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat DUF1640 PF07798.6 EDO18840.1 - 6.4e-64 215.2 7.8 7.4e-64 215.0 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3523 PF12037.3 EDO18840.1 - 0.00075 18.5 4.9 0.00097 18.1 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) DUF1732 PF08340.6 EDO18840.1 - 0.0019 17.9 5.3 0.0019 17.9 3.6 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1732) IFT57 PF10498.4 EDO18840.1 - 0.0027 16.4 10.9 0.0032 16.2 7.5 1.1 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 T2SM PF04612.7 EDO18840.1 - 0.015 15.1 0.2 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M TBPIP PF07106.8 EDO18840.1 - 0.042 13.4 7.4 0.067 12.7 5.1 1.4 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 EDO18840.1 - 0.055 13.1 1.5 0.055 13.1 1.1 1.8 2 0 0 2 2 1 0 Homeobox associated leucine zipper FTA4 PF13093.1 EDO18840.1 - 0.057 12.8 5.3 0.074 12.4 3.7 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3410 PF11890.3 EDO18840.1 - 0.061 12.9 2.5 0.077 12.6 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) DUF615 PF04751.9 EDO18840.1 - 0.088 12.4 5.2 0.092 12.3 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF615) Ima1_N PF09779.4 EDO18840.1 - 0.12 12.8 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Ima1 N-terminal domain V_ATPase_I PF01496.14 EDO18840.1 - 0.14 10.0 4.0 0.16 9.8 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EDO18840.1 - 0.18 10.1 6.3 0.21 9.9 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ApoLp-III PF07464.6 EDO18840.1 - 0.2 11.6 5.4 1.4 8.9 0.4 2.6 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) FlaC_arch PF05377.6 EDO18840.1 - 0.55 10.1 3.2 4.3 7.3 0.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF896 PF05979.7 EDO18840.1 - 0.93 9.1 4.6 0.95 9.0 0.9 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF896) Phage_lysis PF03245.8 EDO18840.1 - 2.7 7.9 8.5 7.3 6.6 0.2 2.4 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein Atg14 PF10186.4 EDO18840.1 - 5.5 5.8 9.2 0.55 9.1 3.1 1.6 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 YlqD PF11068.3 EDO18840.1 - 5.6 7.0 11.2 3.9 7.5 2.6 2.2 1 1 1 2 2 2 0 YlqD protein PMM PF03332.8 EDO18841.1 - 1.7e-112 374.3 0.5 1.9e-112 374.1 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EDO18841.1 - 3e-06 27.0 0.0 2.8e-05 23.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EDO18841.1 - 0.0018 17.4 0.1 0.0027 16.8 0.1 1.2 1 0 0 1 1 1 1 TMPIT-like protein Chordopox_A13L PF05961.6 EDO18841.1 - 0.1 12.5 0.1 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Ribosomal_L16 PF00252.13 EDO18842.1 - 3e-34 117.6 0.1 3.8e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-C2H2_jaz PF12171.3 EDO18843.1 - 2e-09 37.3 5.7 4.5e-09 36.2 4.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EDO18843.1 - 0.00052 20.0 0.4 0.00089 19.3 0.3 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) EFG_II PF14492.1 EDO18843.1 - 0.097 12.5 0.2 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II DUF2960 PF11173.3 EDO18843.1 - 0.11 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) zf-U1 PF06220.7 EDO18843.1 - 0.17 11.4 2.2 0.31 10.6 1.5 1.3 1 0 0 1 1 1 0 U1 zinc finger zf-met PF12874.2 EDO18843.1 - 1.5 9.0 6.8 1.4 9.2 3.2 2.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type OTU PF02338.14 EDO18844.1 - 6.5e-12 46.0 0.0 1.1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EDO18844.1 - 0.0062 15.9 0.3 0.0096 15.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase C65 Otubain Peptidase_C36 PF05415.6 EDO18844.1 - 0.0095 15.8 0.2 0.016 15.0 0.1 1.3 1 0 0 1 1 1 1 Beet necrotic yellow vein furovirus-type papain-like endopeptidase DUF2122 PF09895.4 EDO18844.1 - 0.076 13.2 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) GRAM PF02893.15 EDO18845.1 - 4.5e-11 42.1 0.5 1.1e-10 40.8 0.4 1.6 1 0 0 1 1 1 1 GRAM domain GTP_EFTU PF00009.22 EDO18846.1 - 1.6e-59 200.5 0.0 4.1e-59 199.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EDO18846.1 - 2.6e-35 120.6 0.0 6.2e-35 119.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EDO18846.1 - 2.3e-30 104.2 0.0 5.1e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EDO18846.1 - 2.9e-24 84.7 0.0 7.4e-24 83.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EDO18846.1 - 5.2e-13 48.9 0.2 1.8e-12 47.1 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 EDO18846.1 - 0.043 14.3 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein SPC22 PF04573.7 EDO18847.1 - 5e-53 178.9 2.2 6.2e-53 178.6 1.5 1.1 1 0 0 1 1 1 1 Signal peptidase subunit Sugar_tr PF00083.19 EDO18848.1 - 7.7e-56 189.5 26.7 9.4e-56 189.2 18.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EDO18848.1 - 8.7e-22 77.3 34.8 1.1e-19 70.4 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Actin PF00022.14 EDO18849.1 - 3.7e-08 32.2 0.0 3.7e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 Actin Actin PF00022.14 EDO18850.1 - 3.7e-113 377.9 0.0 4.2e-113 377.7 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EDO18850.1 - 0.026 14.9 0.0 0.14 12.6 0.0 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF788 PF05620.6 EDO18851.1 - 1.4e-56 191.0 1.1 1.5e-56 190.8 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Ras PF00071.17 EDO18852.1 - 8e-65 217.1 0.5 9.6e-65 216.8 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EDO18852.1 - 7.2e-20 71.6 0.1 1.3e-19 70.8 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EDO18852.1 - 5.4e-17 61.5 0.2 7.1e-17 61.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EDO18852.1 - 1.5e-07 30.7 0.4 2.3e-07 30.2 0.3 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO18852.1 - 5.2e-06 26.0 0.1 1e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EDO18852.1 - 7e-05 22.7 0.1 9.9e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EDO18852.1 - 0.0019 17.4 0.3 0.003 16.8 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EDO18852.1 - 0.012 15.6 0.0 0.023 14.8 0.0 1.6 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 EDO18852.1 - 0.019 14.1 0.0 0.038 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 EDO18852.1 - 0.034 13.4 0.3 0.23 10.7 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B YTH PF04146.10 EDO18852.1 - 0.037 13.6 0.2 0.05 13.1 0.1 1.2 1 0 0 1 1 1 0 YT521-B-like domain AAA_5 PF07728.9 EDO18852.1 - 0.038 13.7 0.1 0.059 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO18852.1 - 0.049 13.6 0.1 0.15 12.0 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EDO18852.1 - 0.054 13.0 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EDO18852.1 - 0.059 12.3 0.2 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 Septin LANC_like PF05147.8 EDO18852.1 - 0.071 11.6 0.6 0.95 7.9 0.1 2.0 1 1 1 2 2 2 0 Lanthionine synthetase C-like protein AAA PF00004.24 EDO18852.1 - 0.078 13.1 0.1 0.96 9.6 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EDO18852.1 - 0.099 12.9 1.4 0.38 11.0 1.0 2.0 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 EDO18852.1 - 2.3 6.7 5.9 11 4.6 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit UPF0121 PF03661.8 EDO18853.1 - 0.0003 20.0 17.6 0.00045 19.5 12.2 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) PLA2_B PF01735.13 EDO18854.1 - 9.7e-186 617.7 2.3 1.3e-185 617.2 1.6 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF2331 PF10093.4 EDO18854.1 - 0.12 11.1 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2331) DNA_pol_viral_N PF00242.12 EDO18854.1 - 4.3 6.2 8.3 6 5.7 5.7 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 EDO18854.1 - 7.5 4.7 10.8 11 4.1 7.5 1.2 1 0 0 1 1 1 0 Transmembrane protein PX PF00787.19 EDO18855.1 - 1.5e-18 66.6 1.3 6.7e-18 64.5 0.0 2.6 3 0 0 3 3 3 1 PX domain Latarcin PF10279.4 EDO18855.1 - 0.039 14.1 0.1 0.039 14.1 0.1 2.9 3 1 0 3 3 3 0 Latarcin precursor DUF2404 PF10296.4 EDO18856.1 - 4.6e-07 29.8 0.2 0.00021 21.3 0.0 2.9 3 0 0 3 3 3 2 Putative integral membrane protein conserved region (DUF2404) Pkinase PF00069.20 EDO18857.1 - 2.5e-74 249.7 0.1 4.4e-74 248.9 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18857.1 - 2.4e-42 144.8 0.0 4.3e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EDO18857.1 - 6.4e-30 102.9 0.8 5.3e-17 61.5 0.2 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EDO18857.1 - 1e-09 37.8 0.0 5e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDO18857.1 - 0.018 14.1 0.0 0.052 12.6 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO18857.1 - 0.071 12.8 0.1 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Chitin_synth_1 PF01644.12 EDO18858.1 - 5e-75 250.7 0.5 9.6e-75 249.8 0.4 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EDO18858.1 - 6e-27 93.1 0.1 2.2e-26 91.3 0.1 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EDO18858.1 - 6.8e-22 77.5 9.9 1.1e-15 57.0 0.0 2.7 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EDO18858.1 - 2.5e-12 46.9 0.4 2.5e-12 46.9 0.3 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDO18858.1 - 8.2e-10 38.8 0.0 2.3e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EDO18858.1 - 0.0009 18.9 0.7 0.36 10.4 0.0 3.4 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EDO18858.1 - 0.15 11.3 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 Nramp PF01566.13 EDO18859.1 - 4.4e-96 321.7 14.3 5.9e-96 321.3 9.9 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Bromodomain PF00439.20 EDO18860.1 - 1e-08 34.9 1.7 1.8e-08 34.1 0.4 2.1 2 0 0 2 2 2 1 Bromodomain HA2 PF04408.18 EDO18861.1 - 1.6e-26 92.2 1.3 1.2e-25 89.4 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EDO18861.1 - 3.5e-14 52.4 0.0 2.4e-13 49.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EDO18861.1 - 9.5e-14 51.1 0.0 2.8e-13 49.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EDO18861.1 - 3.8e-09 36.2 0.0 1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EDO18861.1 - 2.9e-06 27.4 0.5 1.4e-05 25.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 EDO18861.1 - 0.0042 16.2 1.4 0.015 14.4 0.0 2.5 3 0 0 3 3 3 1 KaiC T2SE PF00437.15 EDO18861.1 - 0.016 14.0 0.0 0.03 13.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EDO18861.1 - 0.09 12.2 0.1 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EDO18861.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MOZ_SAS PF01853.13 EDO18862.1 - 6.6e-58 195.0 1.9 1.1e-57 194.3 1.3 1.4 1 0 0 1 1 1 1 MOZ/SAS family DUF4555 PF15093.1 EDO18862.1 - 0.11 11.3 0.3 0.16 10.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4555) SNF2_N PF00176.18 EDO18863.1 - 2.8e-61 206.9 0.0 4.5e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EDO18863.1 - 5.8e-16 58.3 0.0 1.8e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EDO18863.1 - 3.4e-11 42.8 0.0 1.2e-10 41.0 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EDO18863.1 - 1.4e-09 37.6 10.2 2.6e-09 36.7 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDO18863.1 - 7.1e-08 31.9 9.0 1.2e-07 31.2 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO18863.1 - 1.6e-07 31.1 11.6 3.3e-07 30.2 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO18863.1 - 3.5e-06 26.5 13.3 7.5e-06 25.5 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO18863.1 - 5.4e-06 26.0 12.3 1e-05 25.1 8.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EDO18863.1 - 4.3e-05 23.2 4.2 8.2e-05 22.3 2.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DEAD PF00270.24 EDO18863.1 - 4.7e-05 22.9 0.0 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 EDO18863.1 - 0.0015 18.1 7.3 0.0059 16.3 5.1 2.1 1 0 0 1 1 1 1 RING-type zinc-finger DUF1505 PF07403.6 EDO18863.1 - 0.055 13.4 3.2 0.14 12.0 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) zf-RING_4 PF14570.1 EDO18863.1 - 0.14 11.7 11.5 0.31 10.6 8.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EDO18863.1 - 0.15 12.1 5.7 0.34 11.0 4.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_8 PF13181.1 EDO18863.1 - 0.16 11.8 2.7 0.21 11.4 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.1 EDO18863.1 - 0.5 10.2 12.0 1.3 8.9 8.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RNase_P_p30 PF01876.11 EDO18864.1 - 2.1e-51 173.0 0.1 3.3e-51 172.4 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit p30 PBD PF00786.23 EDO18865.1 - 1.2 9.5 7.7 0.13 12.6 0.8 2.9 3 1 0 3 3 3 0 P21-Rho-binding domain MIR PF02815.14 EDO18866.1 - 1.6e-15 57.1 0.7 5.4e-15 55.4 0.7 1.8 1 1 1 2 2 2 1 MIR domain PMT PF02366.13 EDO18866.1 - 3.6e-15 55.9 20.7 7.8e-15 54.9 14.3 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase LRR_5 PF13306.1 EDO18867.1 - 0.0043 16.7 0.8 0.17 11.6 0.0 3.0 2 2 0 2 2 2 1 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EDO18867.1 - 0.024 14.3 0.5 0.54 10.0 0.1 3.5 4 0 0 4 4 4 0 Leucine rich repeat IGR PF09597.5 EDO18868.1 - 1.3e-20 73.0 0.4 1.9e-20 72.4 0.2 1.3 1 0 0 1 1 1 1 IGR protein motif Lipoprotein_20 PF13942.1 EDO18868.1 - 0.045 13.2 0.2 0.067 12.7 0.1 1.3 1 0 0 1 1 1 0 YfhG lipoprotein Med6 PF04934.9 EDO18869.1 - 4.5e-51 172.0 22.7 6.4e-49 165.1 15.7 2.5 1 1 0 1 1 1 1 MED6 mediator sub complex component CoA_trans PF01144.18 EDO18869.1 - 0.096 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Coenzyme A transferase Suf PF05843.9 EDO18869.1 - 1.3 8.7 15.1 0.28 10.8 6.2 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 EDO18869.1 - 1.5 8.5 14.6 0.76 9.5 6.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) DUF3154 PF11351.3 EDO18869.1 - 6.8 6.4 7.0 15 5.3 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) Pro_isomerase PF00160.16 EDO18870.1 - 3.3e-44 150.8 0.0 3.9e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.16 EDO18871.1 - 1.7e-46 158.2 0.4 2.1e-46 157.9 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Zn_clus PF00172.13 EDO18872.1 - 4.3e-08 32.9 7.6 7.5e-08 32.1 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AIM24 PF01987.12 EDO18873.1 - 2.3e-09 37.0 0.0 1.4e-08 34.4 0.0 2.1 2 1 0 2 2 2 1 Mitochondrial biogenesis AIM24 PIG-F PF06699.6 EDO18874.1 - 6.5e-44 150.1 19.5 4.9e-43 147.2 13.5 1.9 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F TauE PF01925.14 EDO18874.1 - 0.21 11.0 11.0 1.4 8.3 1.5 2.2 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE CPSF_A PF03178.10 EDO18875.1 - 2.5e-83 279.8 0.2 2.5e-83 279.8 0.2 2.7 3 1 1 4 4 4 1 CPSF A subunit region DUF2457 PF10446.4 EDO18875.1 - 2.8 6.5 10.3 5.3 5.6 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EDO18875.1 - 8.3 5.9 10.8 0.16 11.4 2.2 2.0 2 0 0 2 2 2 0 Nucleoplasmin AA_kinase PF00696.23 EDO18876.1 - 1.7e-35 122.7 0.3 2.4e-35 122.2 0.2 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EDO18876.1 - 8.1e-20 70.3 0.1 2e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 PUA domain OSCP PF00213.13 EDO18877.1 - 5.6e-11 42.6 0.1 6.3e-11 42.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit AF0941-like PF14591.1 EDO18877.1 - 0.014 15.4 0.2 0.018 15.0 0.1 1.1 1 0 0 1 1 1 0 AF0941-like DUF2363 PF10155.4 EDO18877.1 - 0.027 14.4 0.3 0.29 11.0 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2363) DUF1487 PF07368.6 EDO18877.1 - 0.039 13.1 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Ub-RnfH PF03658.9 EDO18877.1 - 0.044 13.6 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 RnfH family Ubiquitin Spo0A_C PF08769.6 EDO18877.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal FA_hydroxylase PF04116.8 EDO18878.1 - 5.6e-18 65.4 8.1 5.6e-18 65.4 5.6 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Brr6_like_C_C PF10104.4 EDO18879.1 - 1.4e-45 154.1 6.2 2.5e-45 153.3 4.3 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Flavi_glycoprot PF00869.15 EDO18879.1 - 0.0068 15.4 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Flavivirus glycoprotein, central and dimerisation domains DUF3835 PF12927.2 EDO18879.1 - 0.071 14.0 3.2 0.19 12.7 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) Aldedh PF00171.17 EDO18880.1 - 3.1e-94 315.9 0.0 4.4e-94 315.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RNB PF00773.14 EDO18881.1 - 1.9e-55 188.4 1.7 1.9e-55 188.4 1.2 2.5 3 0 0 3 3 3 1 RNB domain OB_RNB PF08206.6 EDO18881.1 - 0.00029 20.2 0.1 0.43 10.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease B OB domain Aldedh PF00171.17 EDO18882.1 - 8.1e-110 367.2 0.0 9.4e-110 367.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EDO18882.1 - 0.0046 15.7 0.2 0.11 11.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) FAM222A PF15258.1 EDO18882.1 - 0.068 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein family of FAM222A DUF3232 PF11554.3 EDO18882.1 - 0.071 13.0 0.0 7.4 6.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) V-ATPase_G PF03179.10 EDO18883.1 - 1.4e-29 102.4 8.3 1.5e-29 102.3 5.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EDO18883.1 - 0.024 14.4 11.3 0.057 13.2 7.8 1.5 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Prominin PF05478.6 EDO18883.1 - 0.11 10.0 0.7 0.11 10.0 0.5 1.0 1 0 0 1 1 1 0 Prominin DUF3552 PF12072.3 EDO18883.1 - 0.23 10.6 12.2 0.21 10.7 6.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) zf-HIT PF04438.11 EDO18884.1 - 4.4e-08 32.6 13.6 8.8e-08 31.6 9.4 1.5 1 0 0 1 1 1 1 HIT zinc finger SR-25 PF10500.4 EDO18884.1 - 0.18 11.2 13.0 0.4 10.1 9.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.7 EDO18884.1 - 0.78 7.9 11.7 1.1 7.3 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF4614 PF15391.1 EDO18884.1 - 4.6 6.9 9.8 10 5.8 6.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SRX PF09201.5 EDO18885.1 - 3.5e-71 237.6 5.0 8.3e-71 236.4 3.4 1.7 1 0 0 1 1 1 1 SRX SRP54 PF00448.17 EDO18885.1 - 2.7e-47 160.7 0.3 7.2e-45 152.8 0.2 2.5 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EDO18885.1 - 1.4e-06 27.8 6.6 4.7e-06 26.1 3.9 2.2 2 0 0 2 2 2 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 EDO18885.1 - 8.3e-06 25.3 0.1 1.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 EDO18885.1 - 2.4e-05 24.3 0.1 2.4e-05 24.3 0.1 2.4 3 0 0 3 3 3 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EDO18885.1 - 0.00035 19.4 0.1 0.0011 17.8 0.0 2.0 2 1 0 2 2 2 1 ArgK protein ArsA_ATPase PF02374.10 EDO18885.1 - 0.0009 18.3 1.9 0.11 11.5 0.0 3.3 3 0 0 3 3 3 1 Anion-transporting ATPase MobB PF03205.9 EDO18885.1 - 0.0033 17.1 0.0 0.011 15.4 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_NifH PF00142.13 EDO18885.1 - 0.017 14.3 0.1 0.042 13.0 0.0 1.7 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 EDO18885.1 - 0.032 14.3 0.2 0.23 11.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EDO18885.1 - 0.049 13.6 0.2 0.22 11.4 0.0 2.0 1 1 0 2 2 2 0 AAA ATPase domain NAD_binding_10 PF13460.1 EDO18885.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding DEAD PF00270.24 EDO18886.1 - 4.9e-23 81.4 0.0 1.1e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 EDO18886.1 - 1.7e-15 57.3 0.1 4.6e-15 55.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 EDO18886.1 - 5.5e-13 48.5 0.3 1.9e-11 43.6 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CDT1 PF08839.6 EDO18886.1 - 1.9e-06 27.9 1.7 5.4e-06 26.4 1.2 1.8 1 0 0 1 1 1 1 DNA replication factor CDT1 like Terminase_GpA PF05876.7 EDO18886.1 - 0.14 10.4 0.0 0.25 9.6 0.0 1.3 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) UvsY PF11056.3 EDO18887.1 - 0.11 12.5 0.3 0.11 12.5 0.2 1.8 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY Acetyltransf_1 PF00583.19 EDO18888.1 - 2.6e-16 59.4 0.0 4.5e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EDO18888.1 - 5.4e-06 26.0 0.0 9.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EDO18888.1 - 5.4e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EDO18888.1 - 0.0001 22.3 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO18888.1 - 0.0076 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EDO18888.1 - 0.014 15.5 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EDO18888.1 - 0.073 12.9 0.0 0.2 11.5 0.0 1.8 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Cytokin_check_N PF10407.4 EDO18888.1 - 0.1 12.2 1.8 2.9 7.5 0.0 3.3 3 1 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus Metallophos_2 PF12850.2 EDO18889.1 - 1.4e-15 57.4 0.0 2.2e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GAGA_bind PF06217.7 EDO18889.1 - 0.014 15.3 9.5 0.019 14.9 6.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Vfa1 PF08432.5 EDO18889.1 - 0.94 9.4 20.4 1.6 8.6 14.1 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2201_N PF13203.1 EDO18889.1 - 5.5 6.0 13.3 7.3 5.6 9.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain HSP90 PF00183.13 EDO18889.1 - 5.8 5.1 22.5 8 4.7 15.6 1.1 1 0 0 1 1 1 0 Hsp90 protein Rtf2 PF04641.7 EDO18889.1 - 8.3 5.5 21.3 12 5.0 14.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger tRNA-synt_2b PF00587.20 EDO18890.1 - 2.2e-22 79.4 0.0 3.2e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EDO18890.1 - 4e-05 23.5 3.1 7.7e-05 22.6 2.2 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DicB PF05358.6 EDO18890.1 - 0.0062 15.9 0.4 0.019 14.4 0.2 1.9 1 1 0 1 1 1 1 DicB protein LOH1CR12 PF10158.4 EDO18890.1 - 0.022 14.5 0.6 0.058 13.1 0.4 1.7 1 1 0 1 1 1 0 Tumour suppressor protein DUF1978 PF09321.5 EDO18890.1 - 0.055 12.9 0.5 0.085 12.2 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) FliD_N PF02465.13 EDO18890.1 - 0.18 12.2 0.2 0.18 12.2 0.1 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DAO PF01266.19 EDO18891.1 - 3.6e-52 177.4 0.0 1.1e-51 175.8 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO18891.1 - 5.3e-06 26.3 0.1 1.4e-05 25.0 0.1 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EDO18891.1 - 0.00032 19.4 0.1 0.065 11.8 0.2 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Strep_67kDa_ant PF06100.6 EDO18891.1 - 0.0015 17.0 0.3 0.0023 16.3 0.2 1.2 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_9 PF13454.1 EDO18891.1 - 0.011 15.5 0.1 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EDO18891.1 - 0.017 15.0 0.0 0.23 11.3 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDO18891.1 - 0.021 13.9 0.3 0.042 12.9 0.2 1.4 1 0 0 1 1 1 0 Thi4 family p450 PF00067.17 EDO18892.1 - 1.5e-91 307.2 0.1 1.7e-91 307.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3641 PF12345.3 EDO18892.1 - 0.014 15.2 0.2 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) DUF3020 PF11223.3 EDO18893.1 - 1.9e-18 66.6 37.3 6.9e-12 45.5 14.8 9.8 11 0 0 11 11 11 2 Protein of unknown function (DUF3020) zf-C2H2 PF00096.21 EDO18894.1 - 3.5e-05 23.8 12.0 0.00032 20.8 1.5 3.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO18894.1 - 0.0018 18.5 14.7 0.0078 16.4 0.8 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO18894.1 - 0.0031 17.7 1.2 0.0031 17.7 0.8 3.6 3 0 0 3 3 3 1 Zinc-finger double domain PyrI_C PF02748.10 EDO18894.1 - 0.025 14.0 0.2 0.1 12.0 0.0 2.1 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Rep_fac-A_C PF08646.5 EDO18894.1 - 0.22 11.2 2.6 0.19 11.4 0.2 2.0 2 0 0 2 2 2 0 Replication factor-A C terminal domain TPT PF03151.11 EDO18895.1 - 5.8e-31 107.2 3.5 5.8e-31 107.2 2.4 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EDO18895.1 - 1.3e-12 47.2 16.7 7e-12 44.8 11.6 2.0 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EDO18895.1 - 0.00037 19.6 2.7 0.0026 16.8 0.3 2.3 2 1 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 EDO18895.1 - 0.0015 18.5 28.5 0.0022 18.0 5.1 3.3 5 0 0 5 5 5 2 EamA-like transporter family DUF1201 PF06716.6 EDO18895.1 - 0.03 14.1 0.5 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) EmrE PF13536.1 EDO18895.1 - 0.42 10.8 15.9 0.023 14.9 2.9 3.1 2 1 0 2 2 2 0 Multidrug resistance efflux transporter MRP-L28 PF09812.4 EDO18896.1 - 2.4e-38 131.4 1.6 3e-38 131.1 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 SynMuv_product PF06047.6 EDO18896.1 - 0.035 13.8 0.4 0.067 12.9 0.3 1.5 1 1 0 1 1 1 0 Ras-induced vulval development antagonist CGI-121 PF08617.5 EDO18897.1 - 5.5e-37 126.9 0.4 6.9e-37 126.6 0.3 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF4478 PF14793.1 EDO18897.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4478) MAT1 PF06391.8 EDO18898.1 - 9.6e-60 201.5 22.6 1.1e-59 201.3 15.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EDO18898.1 - 0.0013 18.3 2.8 0.0037 16.8 1.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO18898.1 - 0.0014 18.5 5.1 0.0032 17.4 3.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO18898.1 - 0.023 14.4 6.0 0.049 13.3 4.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDO18898.1 - 0.023 14.3 5.6 0.042 13.5 3.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EDO18898.1 - 0.034 13.9 6.4 0.065 13.0 4.4 1.5 1 0 0 1 1 1 0 Ring finger domain Spectrin PF00435.16 EDO18898.1 - 0.052 13.8 9.4 0.11 12.7 5.8 2.1 1 1 0 1 1 1 0 Spectrin repeat 3HCDH_N PF02737.13 EDO18898.1 - 0.11 12.1 2.6 0.19 11.3 1.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3H PF02829.9 EDO18898.1 - 0.2 11.7 2.3 0.3 11.1 0.6 2.0 2 0 0 2 2 2 0 3H domain zf-RING_UBOX PF13445.1 EDO18898.1 - 0.36 10.5 4.4 0.98 9.1 3.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EDO18898.1 - 0.53 9.8 7.1 1.5 8.4 4.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain UPF0122 PF04297.9 EDO18898.1 - 1.9 8.5 12.6 0.65 10.0 4.7 2.7 1 1 1 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like FKBP_N PF01346.13 EDO18898.1 - 5.8 6.9 12.3 3.6 7.6 5.3 2.4 2 1 1 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase A_deaminase PF00962.17 EDO18899.1 - 5e-118 393.7 0.9 6.2e-118 393.4 0.1 1.6 2 0 0 2 2 2 1 Adenosine/AMP deaminase MSC PF09402.5 EDO18900.1 - 4.4e-96 321.5 4.5 4.4e-96 321.5 3.1 2.2 2 1 0 2 2 2 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EDO18900.1 - 8.5e-14 50.8 0.7 2.8e-13 49.1 0.2 2.3 2 0 0 2 2 2 1 HeH/LEM domain ABC2_membrane_3 PF12698.2 EDO18900.1 - 0.076 12.0 6.6 0.13 11.2 4.6 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein HECT PF00632.20 EDO18901.1 - 1.5e-90 303.5 3.7 2.1e-90 303.1 0.3 3.0 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EDO18901.1 - 2.5e-75 253.8 6.3 2.5e-75 253.8 4.4 4.1 5 1 0 5 5 5 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 EDO18901.1 - 9.1e-47 159.5 0.2 9.1e-47 159.5 0.2 3.2 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 EDO18901.1 - 1.8e-16 59.9 2.4 8.2e-16 57.8 1.7 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) Rad52_Rad22 PF04098.10 EDO18902.1 - 5e-57 191.9 0.0 9.3e-57 191.0 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Ndc1_Nup PF09531.5 EDO18903.1 - 1.7e-133 446.2 24.4 3e-133 445.4 16.9 1.3 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Na_H_Exchanger PF00999.16 EDO18904.1 - 2.9e-67 226.8 34.3 3.6e-67 226.5 23.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Guanylate_kin PF00625.16 EDO18905.1 - 9.2e-67 224.0 0.0 1e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_22 PF13401.1 EDO18905.1 - 3.1e-06 27.3 0.0 9.6e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDO18905.1 - 1.3e-05 25.1 0.0 3.7e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO18905.1 - 1.4e-05 25.1 0.1 9.6e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EDO18905.1 - 1.5e-05 25.7 0.0 3.2e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO18905.1 - 4.9e-05 23.6 0.0 0.00013 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EDO18905.1 - 0.00039 19.9 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_14 PF13173.1 EDO18905.1 - 0.00041 20.2 0.0 0.00088 19.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDO18905.1 - 0.00042 20.2 0.1 0.00097 19.0 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 EDO18905.1 - 0.00057 20.0 0.0 0.0014 18.7 0.0 1.7 1 1 0 1 1 1 1 RNA helicase DUF258 PF03193.11 EDO18905.1 - 0.0014 17.8 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 EDO18905.1 - 0.0014 18.6 0.1 0.0028 17.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EDO18905.1 - 0.0014 18.7 0.2 0.012 15.8 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EDO18905.1 - 0.0015 19.0 0.0 0.0028 18.1 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EDO18905.1 - 0.0015 18.8 0.0 0.0027 17.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 EDO18905.1 - 0.0016 18.0 0.0 0.0078 15.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 EDO18905.1 - 0.004 16.6 1.0 0.018 14.5 0.0 2.3 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EDO18905.1 - 0.0043 16.7 0.0 0.015 15.0 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 EDO18905.1 - 0.0064 15.4 0.0 0.02 13.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein Rad17 PF03215.10 EDO18905.1 - 0.0069 15.1 0.0 0.009 14.7 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EDO18905.1 - 0.015 14.9 0.2 0.041 13.5 0.0 1.8 2 1 0 2 2 2 0 Archaeal ATPase NTPase_1 PF03266.10 EDO18905.1 - 0.017 14.7 0.2 0.036 13.7 0.0 1.6 2 0 0 2 2 1 0 NTPase KAP_NTPase PF07693.9 EDO18905.1 - 0.035 13.1 0.0 0.058 12.3 0.0 1.5 1 1 1 2 2 2 0 KAP family P-loop domain AAA_23 PF13476.1 EDO18905.1 - 0.036 14.3 1.5 0.054 13.8 0.5 1.8 1 1 0 2 2 1 0 AAA domain DUF2075 PF09848.4 EDO18905.1 - 0.04 12.9 0.0 0.096 11.6 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 EDO18905.1 - 0.042 13.4 1.3 0.14 11.7 0.9 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDO18905.1 - 0.053 12.9 0.1 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EDO18905.1 - 0.061 13.0 0.2 0.43 10.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EDO18905.1 - 0.061 13.2 0.0 0.66 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) MobB PF03205.9 EDO18905.1 - 0.061 13.0 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EDO18905.1 - 0.069 12.6 0.1 0.24 10.8 0.1 1.8 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EDO18905.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EDO18905.1 - 0.1 12.0 0.1 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HIG_1_N PF04588.8 EDO18906.1 - 4.2e-21 74.4 1.8 6e-21 73.9 1.2 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2570 PF10828.3 EDO18906.1 - 0.0031 17.0 4.1 0.005 16.4 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2570) DUF2252 PF10009.4 EDO18906.1 - 0.014 14.3 1.7 0.013 14.3 1.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Hormone_1 PF00103.15 EDO18906.1 - 0.031 13.6 5.5 0.043 13.1 3.8 1.2 1 0 0 1 1 1 0 Somatotropin hormone family AAA_23 PF13476.1 EDO18906.1 - 0.032 14.5 5.2 0.03 14.6 3.6 1.2 1 0 0 1 1 1 0 AAA domain DUF4458 PF14660.1 EDO18906.1 - 0.06 13.3 0.3 0.2 11.6 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4458) Pinin_SDK_memA PF04696.8 EDO18906.1 - 1.2 8.7 17.5 2 8.0 12.1 1.3 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Amastin PF07344.6 EDO18907.1 - 0.011 15.3 0.2 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein ubiquitin PF00240.18 EDO18907.1 - 0.019 14.3 1.0 0.059 12.7 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin family AhpC-TSA PF00578.16 EDO18908.1 - 9.2e-34 115.8 0.0 1.7e-33 114.8 0.0 1.4 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EDO18908.1 - 9.3e-20 70.6 0.0 1.5e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EDO18908.1 - 2.7e-11 42.9 0.1 5.5e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Homeobox PF00046.24 EDO18909.1 - 1.1e-13 50.5 2.3 1.8e-13 49.8 1.1 1.8 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EDO18909.1 - 0.02 14.5 0.4 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 Homeobox KN domain PsbW PF07123.7 EDO18909.1 - 0.27 11.3 2.3 0.24 11.4 0.6 1.7 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) Ribosomal_S13 PF00416.17 EDO18910.1 - 9e-43 145.0 1.2 1e-42 144.8 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EDO18910.1 - 0.0011 17.6 0.0 0.0013 17.4 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EDO18910.1 - 0.11 12.6 0.2 0.54 10.3 0.0 2.1 1 1 0 2 2 2 0 Helix-hairpin-helix motif H2TH PF06831.9 EDO18910.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase H2TH domain U3_assoc_6 PF08640.6 EDO18911.1 - 4.3e-33 112.9 7.2 3.2e-32 110.1 0.9 3.1 2 1 1 3 3 3 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 EDO18911.1 - 0.00017 20.5 5.4 0.0021 17.0 0.9 2.7 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference Suf PF05843.9 EDO18911.1 - 0.064 12.9 12.2 0.012 15.4 3.2 3.4 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EDO18911.1 - 0.12 13.0 0.0 3.8 8.4 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat ZZ PF00569.12 EDO18912.1 - 1.8e-16 59.3 7.6 3.1e-16 58.6 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 EDO18912.1 - 1.5e-12 47.4 0.3 1.9e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 EDO18912.1 - 1.1e-06 28.5 0.0 2.7e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EDO18912.1 - 0.029 14.4 1.1 0.08 13.0 0.0 2.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain Ribosomal_S17e PF00833.13 EDO18913.1 - 8.4e-57 190.2 0.3 9.6e-57 190.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Nse5 PF08691.5 EDO18914.1 - 1.4e-177 591.2 36.4 1.7e-177 590.9 25.2 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Metallophos PF00149.23 EDO18915.1 - 3.7e-39 134.1 0.2 7.1e-39 133.2 0.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase LCM PF04072.9 EDO18916.1 - 6.8e-24 84.4 0.0 1e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PIG-S PF10510.4 EDO18917.1 - 2.3e-128 429.0 7.6 2.8e-128 428.8 5.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Methyltransf_11 PF08241.7 EDO18918.1 - 1.1e-12 48.2 0.1 2.5e-12 47.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO18918.1 - 1.6e-05 25.2 0.2 9.4e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO18918.1 - 3.6e-05 23.4 0.1 5.7e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO18918.1 - 5.1e-05 23.0 0.0 0.0001 22.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO18918.1 - 6.4e-05 23.2 0.0 0.00017 21.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO18918.1 - 0.00048 20.6 0.0 0.00092 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EDO18918.1 - 0.0046 16.1 0.0 0.02 14.0 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Phage_Mu_F PF04233.9 EDO18918.1 - 0.083 13.4 0.6 0.14 12.7 0.4 1.4 1 0 0 1 1 1 0 Phage Mu protein F like protein DUF4414 PF14377.1 EDO18918.1 - 0.13 12.1 2.0 0.24 11.3 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Protocadherin PF08374.6 EDO18918.1 - 1.4 8.4 4.9 2.7 7.5 3.3 1.5 1 1 0 1 1 1 0 Protocadherin Peptidase_S49_N PF08496.5 EDO18918.1 - 6.3 6.5 6.3 11 5.7 4.4 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RRM_1 PF00076.17 EDO18919.1 - 5.1e-29 99.7 0.5 9.8e-18 63.5 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO18919.1 - 2e-15 56.4 0.1 5.3e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO18919.1 - 6.8e-12 45.0 0.0 2.2e-10 40.1 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 EDO18919.1 - 0.039 13.9 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain EMP24_GP25L PF01105.19 EDO18920.1 - 6.7e-40 136.7 2.0 8.2e-40 136.4 0.0 1.8 1 1 1 2 2 2 1 emp24/gp25L/p24 family/GOLD Ribosomal_L33 PF00471.15 EDO18921.1 - 0.0014 18.8 0.1 0.0077 16.4 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein L33 eIF3g PF12353.3 EDO18922.1 - 7.6e-46 155.1 2.9 1.2e-45 154.5 2.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EDO18922.1 - 2.1e-13 49.6 0.0 4.6e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO18922.1 - 4.9e-10 39.2 0.0 9.2e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO18922.1 - 3.9e-08 33.0 0.0 7.4e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.22 EDO18923.1 - 3.5e-14 53.0 1.1 3.5e-14 53.0 0.7 2.4 3 0 0 3 3 3 1 PCI domain Spo0A_C PF08769.6 EDO18923.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Sporulation initiation factor Spo0A C terminal PCI_Csn8 PF10075.4 EDO18923.1 - 0.039 13.7 0.9 0.12 12.1 0.6 1.8 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 MutS_III PF05192.13 EDO18923.1 - 0.19 11.5 1.4 0.36 10.5 0.9 1.7 1 1 0 1 1 1 0 MutS domain III PAP1 PF08601.5 EDO18924.1 - 3.9e-39 135.3 40.6 3.9e-39 135.3 28.2 3.9 1 1 1 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.16 EDO18924.1 - 1.3e-06 28.2 12.1 3.1e-06 27.0 8.4 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EDO18924.1 - 0.00024 20.8 9.9 0.00045 19.9 6.8 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EDO18924.1 - 0.36 11.1 8.9 0.72 10.1 6.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor HrpJ PF07201.6 EDO18924.1 - 0.47 10.4 9.3 0.77 9.7 6.5 1.2 1 0 0 1 1 1 0 HrpJ-like domain AMPKBI PF04739.10 EDO18925.1 - 1.2e-23 82.8 0.6 1.2e-23 82.8 0.4 3.1 3 1 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain zf-C2H2 PF00096.21 EDO18927.1 - 2.6e-08 33.7 11.6 0.00085 19.5 1.6 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO18927.1 - 8.9e-08 32.0 8.4 1.4e-05 25.1 3.6 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO18927.1 - 7.4e-05 22.8 12.0 0.011 15.9 1.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-TRAF PF02176.13 EDO18927.1 - 0.22 11.8 2.6 0.45 10.9 1.8 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 EDO18927.1 - 0.38 10.9 2.5 6 7.1 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 EDO18927.1 - 0.44 10.5 2.2 2 8.4 0.0 2.3 2 0 0 2 2 2 0 zinc-finger TFR_dimer PF04253.10 EDO18928.1 - 1.3e-13 50.5 0.0 2.7e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EDO18928.1 - 1.2e-09 38.1 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EDO18928.1 - 0.012 15.3 0.0 0.03 13.9 0.0 1.7 2 0 0 2 2 2 0 PA domain Adaptin_N PF01602.15 EDO18929.1 - 1e-109 367.3 16.5 1.3e-109 366.9 11.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EDO18929.1 - 1.9e-09 37.8 0.0 4.6e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain bZIP_1 PF00170.16 EDO18930.1 - 0.0001 22.1 12.2 0.0001 22.1 8.5 3.0 2 1 0 2 2 2 1 bZIP transcription factor HALZ PF02183.13 EDO18930.1 - 0.0015 18.1 1.5 0.0015 18.1 1.0 1.9 2 0 0 2 2 2 1 Homeobox associated leucine zipper Hap4_Hap_bind PF10297.4 EDO18930.1 - 0.0043 16.8 3.4 0.009 15.8 2.4 1.5 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_2 PF07716.10 EDO18930.1 - 0.012 15.4 6.5 0.012 15.4 4.5 3.0 2 1 1 3 3 3 0 Basic region leucine zipper MbeD_MobD PF04899.7 EDO18930.1 - 0.019 14.8 0.5 0.041 13.7 0.1 1.7 1 1 0 1 1 1 0 MbeD/MobD like bZIP_Maf PF03131.12 EDO18930.1 - 0.035 14.3 3.1 0.13 12.5 2.1 2.0 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF972 PF06156.8 EDO18930.1 - 0.047 14.0 0.2 0.047 14.0 0.2 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Yip1 PF04893.12 EDO18931.1 - 0.0087 15.5 2.5 0.012 15.1 1.8 1.2 1 0 0 1 1 1 1 Yip1 domain EST1_DNA_bind PF10373.4 EDO18931.1 - 1.2 8.3 8.9 2.4 7.2 6.2 1.5 1 1 0 1 1 1 0 Est1 DNA/RNA binding domain Rpr2 PF04032.11 EDO18932.1 - 9.3e-15 54.2 3.2 1.4e-14 53.7 2.2 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Proteasome PF00227.21 EDO18933.1 - 2.8e-55 186.5 0.0 3.6e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EDO18933.1 - 6.6e-14 50.9 0.1 1.4e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MAT_Alpha1 PF04769.7 EDO18934.1 - 4.6e-13 48.9 7.9 2.2e-07 30.4 0.5 2.3 1 1 1 2 2 2 2 Mating-type protein MAT alpha 1 DUF473 PF04322.7 EDO18934.1 - 0.032 13.8 2.3 0.41 10.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF473) Homeobox PF00046.24 EDO18935.1 - 1.7e-07 30.7 0.5 4e-07 29.5 0.3 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EDO18935.1 - 1.5e-06 27.8 0.1 3.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain DUF3290 PF11694.3 EDO18935.1 - 0.025 14.3 3.1 0.64 9.7 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Homez PF11569.3 EDO18935.1 - 0.029 13.4 0.1 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 EDO18935.1 - 0.03 14.4 0.1 0.066 13.3 0.1 1.7 1 1 0 1 1 1 0 Helicase associated domain Leuk-A4-hydro_C PF09127.6 EDO18935.1 - 0.19 11.3 3.1 0.3 10.6 0.1 2.3 1 1 1 2 2 2 0 Leukotriene A4 hydrolase, C-terminal PALP PF00291.20 EDO18936.1 - 1.1e-65 221.8 0.0 1.3e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_4 PF13407.1 EDO18936.1 - 0.019 14.3 0.2 0.048 13.0 0.1 1.7 2 0 0 2 2 2 0 Periplasmic binding protein domain DAGK_cat PF00781.19 EDO18936.1 - 0.024 14.0 0.1 0.7 9.3 0.0 2.5 2 1 0 2 2 2 0 Diacylglycerol kinase catalytic domain Med30 PF11315.3 EDO18937.1 - 0.015 15.4 1.1 0.04 14.0 0.1 2.2 1 1 1 2 2 2 0 Mediator complex subunit 30 MRC1 PF09444.5 EDO18938.1 - 9.9e-44 149.1 16.9 9.9e-44 149.1 11.7 6.7 3 1 1 6 6 6 2 MRC1-like domain KH_1 PF00013.24 EDO18939.1 - 0.00075 19.0 0.0 0.0023 17.5 0.0 1.9 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EDO18939.1 - 0.039 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 KH domain Med3 PF11593.3 EDO18940.1 - 0.041 13.1 4.0 0.043 13.0 2.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3896 PF13035.1 EDO18940.1 - 1.4 8.9 4.5 0.43 10.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) Phage_B PF02304.10 EDO18940.1 - 3.4 7.9 7.3 1.6 8.9 2.1 1.9 1 1 1 2 2 2 0 Scaffold protein B NPR3 PF03666.8 EDO18940.1 - 4.1 5.8 7.7 4.4 5.7 5.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF543 PF04418.7 EDO18941.1 - 7e-31 106.0 0.1 8e-31 105.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Peptidase_M3 PF01432.15 EDO18942.1 - 4.2e-146 487.5 1.1 6e-146 487.0 0.8 1.2 1 0 0 1 1 1 1 Peptidase family M3 Ribosomal_S3_C PF00189.15 EDO18943.1 - 0.075 13.2 0.2 0.12 12.6 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S3, C-terminal domain MT-A70 PF05063.9 EDO18945.1 - 3.9e-12 46.0 0.0 6.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Spb1_C PF07780.7 EDO18946.1 - 2.1e-76 256.1 28.7 2.1e-76 256.1 19.9 3.7 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EDO18946.1 - 4e-55 185.6 20.4 4e-55 185.6 14.1 5.1 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EDO18946.1 - 1.7e-52 178.0 0.1 1.7e-52 178.0 0.0 2.5 3 0 0 3 3 3 1 FtsJ-like methyltransferase PIG-X PF08320.7 EDO18947.1 - 2.8e-55 186.8 0.0 3.8e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 Menin PF05053.8 EDO18948.1 - 0.53 8.3 8.5 0.73 7.9 5.9 1.2 1 0 0 1 1 1 0 Menin ATP_transf PF09830.4 EDO18949.1 - 1.8e-20 72.4 0.0 3.6e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase Fumble PF03630.9 EDO18950.1 - 3.7e-123 410.7 4.5 9.2e-121 402.8 0.9 2.2 1 1 1 2 2 2 2 Fumble BOF PF04076.8 EDO18950.1 - 0.0044 16.8 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 Bacterial OB fold (BOF) protein T4SS PF07996.6 EDO18950.1 - 0.061 13.1 1.8 0.18 11.6 1.4 1.6 2 0 0 2 2 2 0 Type IV secretion system proteins Seryl_tRNA_N PF02403.17 EDO18951.1 - 0.066 13.2 23.4 0.033 14.2 4.1 4.2 3 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Phage_HK97_TLTM PF06120.6 EDO18951.1 - 2.4 7.4 14.4 0.11 11.7 4.0 2.5 1 1 0 2 2 2 0 Tail length tape measure protein EamA PF00892.15 EDO18952.1 - 1.6e-29 102.5 23.9 4.1e-18 65.6 2.9 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EDO18952.1 - 2.7e-08 33.9 7.7 2.7e-08 33.9 5.3 3.6 2 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EDO18952.1 - 0.39 10.3 19.9 0.019 14.5 3.9 3.1 2 1 0 2 2 2 0 Triose-phosphate Transporter family RPAP1_C PF08620.5 EDO18953.1 - 1.5e-31 108.0 0.0 2.9e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EDO18953.1 - 1.9e-14 52.9 5.8 1.9e-14 52.9 4.0 2.2 3 0 0 3 3 3 1 RPAP1-like, N-terminal CtIP_N PF10482.4 EDO18953.1 - 0.0018 18.0 2.7 0.0045 16.7 1.9 1.6 1 0 0 1 1 1 1 Tumour-suppressor protein CtIP N-terminal domain SAS4 PF15460.1 EDO18953.1 - 0.005 16.6 0.5 0.02 14.7 0.4 2.1 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Pkinase PF00069.20 EDO18954.1 - 1.8e-64 217.3 0.0 2.6e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18954.1 - 1.9e-45 154.9 0.0 3e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO18954.1 - 1e-07 31.2 0.0 4e-07 29.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Recep_L_domain PF01030.19 EDO18955.1 - 1.9e-11 43.8 9.1 0.00065 19.6 0.1 4.4 1 1 1 4 4 4 3 Receptor L domain LRR_4 PF12799.2 EDO18955.1 - 0.0082 15.7 8.3 0.032 13.8 0.8 4.0 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EDO18955.1 - 0.042 13.4 0.2 0.12 11.9 0.1 1.8 1 0 0 1 1 1 0 Leucine-rich repeat Phage_Mu_Gp45 PF06890.7 EDO18955.1 - 0.14 11.6 0.8 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein LRR_8 PF13855.1 EDO18955.1 - 0.23 11.2 7.0 0.22 11.3 0.3 3.6 3 1 1 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 EDO18955.1 - 2.9 8.2 5.1 95 3.6 0.2 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat Zn_clus PF00172.13 EDO18956.1 - 0.00017 21.4 5.5 0.00029 20.6 3.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CTP_transf_2 PF01467.21 EDO18957.1 - 3.4e-08 33.7 0.1 1.5e-07 31.5 0.1 1.9 1 1 0 1 1 1 1 Cytidylyltransferase ATP-sulfurylase PF01747.12 EDO18957.1 - 0.061 12.6 0.0 0.22 10.8 0.0 1.9 2 1 0 2 2 2 0 ATP-sulfurylase DUF1620 PF07774.8 EDO18958.1 - 7.3e-74 247.6 0.7 1.4e-73 246.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EDO18958.1 - 0.0025 17.3 0.1 0.032 13.6 0.0 2.3 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 EDO18958.1 - 0.024 14.1 0.0 0.066 12.7 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Mgr1 PF08602.5 EDO18959.1 - 2.2e-129 431.6 1.2 2.2e-129 431.6 0.8 1.6 2 1 0 2 2 2 1 Mgr1-like, i-AAA protease complex subunit Thioredoxin PF00085.15 EDO18960.1 - 5.1e-27 93.5 1.7 6.2e-17 61.1 0.0 4.0 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EDO18960.1 - 8.9e-22 77.7 16.7 1.2e-16 61.0 6.4 3.4 3 0 0 3 3 3 3 Thioredoxin-like domain DUF4121 PF13497.1 EDO18960.1 - 0.041 12.8 0.3 0.074 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) DUF4316 PF14195.1 EDO18960.1 - 0.62 10.1 0.1 0.62 10.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4316) GRASP55_65 PF04495.9 EDO18961.1 - 6.7e-38 129.7 0.1 1.9e-35 121.8 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Hexokinase_2 PF03727.11 EDO18962.1 - 9.2e-89 296.8 0.0 1.2e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EDO18962.1 - 5.1e-69 231.7 0.0 8.4e-69 231.0 0.0 1.3 1 0 0 1 1 1 1 Hexokinase WD40 PF00400.27 EDO18963.1 - 1.3e-24 85.1 1.4 0.00012 21.8 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EDO18963.1 - 0.0015 18.2 0.2 0.086 12.5 0.0 3.2 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EDO18963.1 - 1.1 8.5 2.7 1.1e+02 2.2 0.2 3.8 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature La PF05383.12 EDO18964.1 - 2.6e-19 68.7 0.4 8.1e-19 67.1 0.1 2.0 2 0 0 2 2 2 1 La domain DNA_pol_A_exo1 PF01612.15 EDO18965.1 - 0.0086 15.5 0.0 0.044 13.2 0.0 2.1 1 1 0 1 1 1 1 3'-5' exonuclease Glutaredoxin PF00462.19 EDO18966.1 - 3.9e-13 49.1 0.0 5.5e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.1 EDO18966.1 - 0.0016 18.4 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like DUF1998 PF09369.5 EDO18966.1 - 0.045 14.3 0.1 0.11 13.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1998) Thioredoxin_4 PF13462.1 EDO18966.1 - 0.17 11.8 0.7 3.8 7.5 0.3 2.1 1 1 0 2 2 2 0 Thioredoxin GAT PF03127.9 EDO18967.1 - 5.6e-05 23.0 0.5 0.015 15.2 0.0 2.8 2 1 1 3 3 3 2 GAT domain RRP7 PF12923.2 EDO18968.1 - 1.3e-33 115.8 7.8 1.3e-33 115.8 5.4 2.4 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) DUF814 PF05670.8 EDO18968.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF814) ATP-synt_G PF04718.10 EDO18968.1 - 0.098 13.3 1.5 0.16 12.6 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit HisKA_2 PF07568.7 EDO18968.1 - 0.14 12.0 0.6 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase DUF2344 PF10105.4 EDO18968.1 - 0.14 11.6 3.4 0.38 10.2 1.5 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Complex1_LYR PF05347.10 EDO18969.1 - 1.4e-10 40.8 0.1 4.3e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EDO18969.1 - 4.2e-10 39.6 0.0 1.1e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EDO18969.1 - 8e-06 26.2 0.3 1.6e-05 25.3 0.2 1.6 1 1 0 1 1 1 1 Complex1_LYR-like PMT_C PF11647.3 EDO18969.1 - 0.024 14.2 0.8 0.96 9.1 0.1 2.2 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 FliG_N PF14842.1 EDO18969.1 - 0.075 13.1 0.3 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 FliG N-terminal domain DUF4028 PF13220.1 EDO18969.1 - 0.092 12.3 0.6 0.26 10.9 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4028) MFS_3 PF05977.8 EDO18969.1 - 0.11 10.5 0.1 0.13 10.3 0.1 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector Histidinol_dh PF00815.15 EDO18970.1 - 3.8e-186 618.6 5.4 3.8e-186 618.6 3.8 1.5 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.13 EDO18970.1 - 5.1e-28 96.5 0.1 9.7e-28 95.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EDO18970.1 - 4e-12 46.2 0.4 1e-11 44.9 0.3 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase CAP_GLY PF01302.20 EDO18971.1 - 1.5e-16 59.7 0.2 2.9e-16 58.8 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain Spc7 PF08317.6 EDO18971.1 - 2.2 6.8 37.6 0.049 12.2 8.7 2.5 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF1843 PF08898.5 EDO18971.1 - 8.7 6.4 10.0 37 4.4 2.9 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) TPR_2 PF07719.12 EDO18973.1 - 0.0025 17.6 0.0 0.016 15.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Rad60-SLD PF11976.3 EDO18974.1 - 4.9e-21 74.1 0.2 6.1e-21 73.8 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EDO18974.1 - 1.3e-12 46.9 0.1 1.6e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.20 EDO18975.1 - 8.2e-75 251.2 0.0 2.6e-74 249.6 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO18975.1 - 5.8e-38 130.4 0.0 3.6e-37 127.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO18975.1 - 3.2e-05 23.0 0.0 9.8e-05 21.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EDO18975.1 - 2.3 7.9 4.0 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ank_5 PF13857.1 EDO18976.1 - 2.6e-15 56.0 0.3 8e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO18976.1 - 2.2e-14 53.5 0.1 3.6e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EDO18976.1 - 1.1e-12 47.0 1.1 1.8e-07 30.5 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EDO18976.1 - 5.8e-11 41.5 0.5 2.4e-05 24.1 0.0 3.8 5 0 0 5 5 3 2 Ankyrin repeat Ank_4 PF13637.1 EDO18976.1 - 4.5e-10 39.7 0.2 0.00014 22.2 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Nup54 PF13874.1 EDO18976.1 - 0.0071 16.0 11.8 0.084 12.5 4.0 2.3 2 0 0 2 2 2 2 Nucleoporin complex subunit 54 AAA_23 PF13476.1 EDO18976.1 - 0.022 15.0 9.8 0.036 14.3 0.4 2.5 2 0 0 2 2 2 0 AAA domain Med9 PF07544.8 EDO18976.1 - 0.38 10.5 14.0 0.23 11.1 2.4 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Tropomyosin_1 PF12718.2 EDO18976.1 - 0.46 10.3 19.5 0.072 12.9 5.2 2.3 2 0 0 2 2 2 0 Tropomyosin like WXG100 PF06013.7 EDO18976.1 - 0.58 10.1 5.7 7.2 6.6 0.0 3.5 2 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF3287 PF11690.3 EDO18976.1 - 1.5 8.8 5.8 0.58 10.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) MerR-DNA-bind PF09278.6 EDO18976.1 - 2.6 8.5 13.0 2.5 8.5 1.6 3.1 2 1 1 3 3 3 0 MerR, DNA binding Hormone_1 PF00103.15 EDO18976.1 - 7.8 5.7 10.3 0.67 9.2 1.4 2.5 1 1 2 3 3 3 0 Somatotropin hormone family tRNA-synt_His PF13393.1 EDO18976.1 - 7.9 5.4 8.4 6.9 5.6 1.2 3.0 3 0 0 3 3 3 0 Histidyl-tRNA synthetase Seryl_tRNA_N PF02403.17 EDO18976.1 - 9.5 6.2 22.6 5.2 7.1 5.2 3.1 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Homeobox PF00046.24 EDO18977.1 - 2.9e-14 52.4 0.9 4.7e-14 51.7 0.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EDO18977.1 - 6e-06 25.8 0.4 1.4e-05 24.7 0.1 1.8 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 EDO18977.1 - 0.0028 16.6 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Sec10 PF07393.6 EDO18978.1 - 2.2e-52 178.2 20.8 4.3e-52 177.2 14.4 1.5 1 1 0 1 1 1 1 Exocyst complex component Sec10 RNase_PH PF01138.16 EDO18979.1 - 1.7e-30 106.0 0.2 8.9e-30 103.6 0.1 2.1 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Cdc6_C PF09079.6 EDO18979.1 - 0.083 12.6 0.2 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 CDC6, C terminal ELO PF01151.13 EDO18980.1 - 1.1e-59 201.7 26.9 1.4e-59 201.3 18.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family AAA PF00004.24 EDO18981.1 - 1.8e-10 41.1 0.1 1.1e-09 38.6 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EDO18981.1 - 1.1e-09 38.4 0.0 3.2e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO18981.1 - 6e-07 29.6 0.0 2.7e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EDO18981.1 - 9.8e-05 22.0 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EDO18981.1 - 0.00051 19.9 0.2 0.1 12.5 0.0 2.7 1 1 1 2 2 2 1 AAA domain Cdc6_C PF09079.6 EDO18981.1 - 0.0008 19.0 0.1 0.0018 17.9 0.1 1.6 1 0 0 1 1 1 1 CDC6, C terminal Arch_ATPase PF01637.13 EDO18981.1 - 0.0025 17.5 0.1 0.01 15.5 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EDO18981.1 - 0.012 15.2 0.2 0.68 9.5 0.1 2.5 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EDO18981.1 - 0.02 15.0 0.2 0.49 10.5 0.0 2.8 3 0 0 3 3 3 0 RNA helicase AAA_11 PF13086.1 EDO18981.1 - 0.037 13.6 3.6 0.11 12.0 1.9 2.3 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EDO18981.1 - 0.055 13.2 0.0 6.7 6.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EDO18981.1 - 0.059 12.2 0.2 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EDO18981.1 - 0.087 12.5 0.0 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 NTPase ArgK PF03308.11 EDO18981.1 - 0.088 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein TPT PF03151.11 EDO18982.1 - 1.4e-37 128.7 4.8 1.4e-37 128.7 3.4 3.1 2 1 0 3 3 3 1 Triose-phosphate Transporter family CD20 PF04103.10 EDO18982.1 - 0.0022 17.9 1.7 0.0022 17.9 1.2 2.3 2 0 0 2 2 2 1 CD20-like family EamA PF00892.15 EDO18982.1 - 0.014 15.4 36.3 0.044 13.8 4.0 4.1 3 2 1 4 4 4 0 EamA-like transporter family Beach PF02138.13 EDO18983.1 - 4.6e-108 360.7 0.2 1.7e-107 358.9 0.2 2.1 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EDO18983.1 - 1.5e-13 50.4 0.0 6.4e-13 48.4 0.0 2.2 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EDO18983.1 - 0.14 12.1 0.1 43 4.1 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Ribosomal_S11 PF00411.14 EDO18985.1 - 4.2e-40 136.3 0.9 4.9e-40 136.1 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S11 Mannosyl_trans3 PF11051.3 EDO18986.1 - 6.9e-83 278.1 0.0 1.2e-82 277.2 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative muHD PF10291.4 EDO18987.1 - 1.3e-78 263.7 1.5 1.6e-78 263.4 0.0 1.9 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain SSB PF00436.20 EDO18989.1 - 3.1e-20 71.9 0.1 3.8e-20 71.6 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family MFS_1 PF07690.11 EDO18990.1 - 2.8e-27 95.3 18.8 3.9e-27 94.8 13.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.2 EDO18990.1 - 0.0044 16.8 1.4 0.0044 16.8 1.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3792) Glyco_transf_34 PF05637.7 EDO18991.1 - 7.6e-49 166.3 0.1 1.1e-48 165.9 0.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Prefoldin_2 PF01920.15 EDO18992.1 - 1.4e-12 47.3 8.6 1.6e-12 47.1 6.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit NPV_P10 PF05531.7 EDO18992.1 - 0.011 15.9 6.2 0.64 10.2 1.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Lip_prot_lig_C PF10437.4 EDO18992.1 - 0.099 12.3 1.5 0.1 12.2 0.3 1.6 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Prominin PF05478.6 EDO18992.1 - 0.11 10.0 5.1 0.11 9.9 3.5 1.0 1 0 0 1 1 1 0 Prominin DUF3560 PF12083.3 EDO18992.1 - 0.12 12.4 0.2 0.31 11.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3560) DUF972 PF06156.8 EDO18992.1 - 0.16 12.3 3.7 1.7 9.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EDO18992.1 - 0.19 11.1 11.4 0.77 9.1 1.5 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 ORF6C PF10552.4 EDO18992.1 - 0.25 11.0 5.5 1.3 8.8 0.7 2.0 1 1 1 2 2 2 0 ORF6C domain STAT_alpha PF01017.15 EDO18992.1 - 0.25 11.0 5.6 0.38 10.4 3.9 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain Baculo_PEP_C PF04513.7 EDO18992.1 - 0.31 10.8 5.4 0.67 9.7 1.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cluap1 PF10234.4 EDO18992.1 - 0.32 10.1 6.0 0.45 9.6 4.1 1.3 1 1 0 1 1 1 0 Clusterin-associated protein-1 Seryl_tRNA_N PF02403.17 EDO18992.1 - 0.49 10.4 5.3 2.1 8.3 3.2 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DASH_Hsk3 PF08227.6 EDO18992.1 - 0.61 10.3 3.2 1.1 9.5 2.2 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like IncA PF04156.9 EDO18992.1 - 0.69 9.4 4.9 1.2 8.6 3.3 1.4 1 1 0 1 1 1 0 IncA protein DUF3186 PF11382.3 EDO18992.1 - 1.3 8.0 4.5 5.4 6.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) DUF16 PF01519.11 EDO18992.1 - 1.7 8.9 5.6 0.5 10.6 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 FlaC_arch PF05377.6 EDO18992.1 - 2 8.3 4.1 7.3 6.5 0.7 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF948 PF06103.6 EDO18992.1 - 5.8 6.8 8.2 5.2 7.0 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ATG27 PF09451.5 EDO18993.1 - 3.6e-54 183.8 0.0 4.2e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 ABA_GPCR PF12430.3 EDO18993.1 - 0.078 12.0 0.3 1.5 7.9 0.1 2.6 3 0 0 3 3 3 0 Abscisic acid G-protein coupled receptor FixP_N PF14715.1 EDO18993.1 - 0.31 10.4 5.5 0.65 9.4 3.8 1.5 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Ribosomal_L22 PF00237.14 EDO18994.1 - 4.1e-34 116.6 2.3 4.3e-34 116.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Fis1_TPR_C PF14853.1 EDO18994.1 - 0.11 12.3 0.2 11 6.0 0.0 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat CASP_C PF08172.7 EDO18995.1 - 1.4e-67 227.3 2.4 1.4e-67 227.3 1.7 3.7 3 1 0 3 3 3 1 CASP C terminal Rab5-bind PF09311.6 EDO18995.1 - 1.6e-05 24.8 1.3 1.6e-05 24.8 0.9 4.4 2 1 1 3 3 3 1 Rabaptin-like protein Lipoprotein_20 PF13942.1 EDO18995.1 - 0.012 15.2 3.7 0.012 15.2 2.6 5.0 4 2 2 6 6 6 0 YfhG lipoprotein NPV_P10 PF05531.7 EDO18995.1 - 0.029 14.5 0.7 0.029 14.5 0.5 6.2 4 2 2 7 7 7 0 Nucleopolyhedrovirus P10 protein DUF4140 PF13600.1 EDO18995.1 - 0.061 13.7 0.3 0.061 13.7 0.2 6.7 5 2 1 6 6 6 0 N-terminal domain of unknown function (DUF4140) DASH_Dam1 PF08653.5 EDO18995.1 - 0.35 10.6 7.9 0.56 10.0 0.1 4.4 4 0 0 4 4 4 0 DASH complex subunit Dam1 DASH_Hsk3 PF08227.6 EDO18995.1 - 0.69 10.1 16.2 34 4.7 0.0 6.0 5 0 0 5 5 5 0 DASH complex subunit Hsk3 like DUF3251 PF11622.3 EDO18995.1 - 2.6 7.4 9.7 9.1 5.6 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3251) Rep_fac-A_3 PF08661.6 EDO18996.1 - 2e-30 104.9 0.0 2.2e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 DUF2401 PF10287.4 EDO18997.1 - 1.7e-88 296.1 4.3 2.4e-88 295.5 3.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EDO18997.1 - 5.7e-27 93.6 0.2 1.7e-26 92.1 0.1 1.9 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) AA_permease PF00324.16 EDO18999.1 - 3.5e-81 272.9 46.4 4.7e-81 272.5 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO18999.1 - 1.5e-36 125.9 52.9 1.9e-36 125.5 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease p53-inducible11 PF14936.1 EDO18999.1 - 0.091 12.7 3.8 0.24 11.3 2.6 1.7 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 Aft1_OSA PF11785.3 EDO18999.1 - 0.31 11.6 1.9 0.74 10.3 1.3 1.7 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain MMPL PF03176.10 EDO18999.1 - 2.3 6.8 5.1 0.53 8.9 0.8 1.9 2 0 0 2 2 2 0 MMPL family polyprenyl_synt PF00348.12 EDO19000.1 - 4.9e-85 284.5 0.0 5.8e-85 284.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase UcrQ PF02939.11 EDO19001.1 - 1e-35 121.3 1.0 1.2e-35 121.1 0.7 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 EDO19001.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) Ribosomal_L14 PF00238.14 EDO19002.1 - 2.9e-41 140.0 2.4 3.3e-41 139.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e L51_S25_CI-B8 PF05047.11 EDO19003.1 - 4.2e-14 52.0 1.0 8.1e-14 51.1 0.3 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pkinase PF00069.20 EDO19004.1 - 5.8e-71 238.6 0.0 7.4e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO19004.1 - 1.1e-39 136.1 0.0 1.5e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO19004.1 - 0.0049 15.8 0.0 0.0081 15.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Myc_N PF01056.13 EDO19004.1 - 0.034 13.3 0.7 0.047 12.8 0.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region APH PF01636.18 EDO19004.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EDO19004.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sigma70_ner PF04546.8 EDO19004.1 - 1.9 8.0 6.5 3 7.4 4.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region PIR PF00399.14 EDO19005.1 - 1.2e-16 59.3 32.4 1.3e-06 27.4 3.4 4.3 4 0 0 4 4 4 3 Yeast PIR protein repeat PIR PF00399.14 EDO19006.1 - 2.2e-47 156.8 88.6 2.7e-08 32.8 4.1 7.1 6 0 0 6 6 6 6 Yeast PIR protein repeat TFIIA PF03153.8 EDO19006.1 - 3.1 7.6 17.9 4.2 7.1 12.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIR PF00399.14 EDO19007.1 - 1e-48 161.1 74.4 6.4e-09 34.8 2.4 6.9 6 0 0 6 6 6 6 Yeast PIR protein repeat DUF374 PF04028.8 EDO19007.1 - 0.014 14.5 5.0 4.1 6.6 0.5 4.6 1 1 4 5 5 5 0 Domain of unknown function (DUF374) TFIIA PF03153.8 EDO19007.1 - 2.3 8.0 18.7 2.9 7.7 13.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF966 PF06136.8 EDO19007.1 - 5.1 6.4 13.4 6.7 6.0 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) vWA-TerF-like PF10138.4 EDO19007.1 - 6.3 6.5 10.5 20 4.9 1.4 2.8 1 1 1 2 2 2 0 vWA found in TerF C terminus Vps35 PF03635.12 EDO19008.1 - 4.3e-191 636.9 41.2 5.3e-191 636.6 28.5 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 peroxidase PF00141.18 EDO19009.1 - 7.3e-41 140.1 0.0 1.4e-40 139.2 0.0 1.5 1 1 0 1 1 1 1 Peroxidase Pam17 PF08566.5 EDO19010.1 - 5.6e-74 247.5 0.2 6.6e-74 247.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.11 EDO19010.1 - 0.01 14.8 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Pmp3 PF01679.12 EDO19011.1 - 1.4e-18 66.3 4.4 1.8e-18 65.9 3.0 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Cytochrom_B_N_2 PF13631.1 EDO19011.1 - 0.0076 16.0 0.1 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b(N-terminal)/b6/petB Serglycin PF04360.7 EDO19011.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Serglycin F-box-like PF12937.2 EDO19012.1 - 2.5e-07 30.3 0.6 7.3e-07 28.8 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EDO19012.1 - 3.7e-05 23.2 2.3 7e-05 22.3 0.4 2.5 2 0 0 2 2 2 1 F-box domain Ribonuc_red_sm PF00268.16 EDO19013.1 - 5e-69 232.4 7.8 5.9e-69 232.1 5.4 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain zf-TRAF PF02176.13 EDO19013.1 - 0.0065 16.8 0.1 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 TRAF-type zinc finger LcrV PF04792.7 EDO19013.1 - 0.039 12.9 0.2 0.039 12.9 0.1 3.1 3 2 1 4 4 4 0 V antigen (LcrV) protein Ribonuc_red_sm PF00268.16 EDO19014.1 - 1.4e-118 394.9 3.1 1.9e-118 394.5 2.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Cep57_CLD_2 PF14197.1 EDO19014.1 - 0.15 12.0 3.7 0.3 11.0 2.6 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 MFS_1 PF07690.11 EDO19015.1 - 2.3e-35 121.9 28.1 2.3e-35 121.9 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EDO19015.1 - 1.9e-05 23.0 2.9 1.9e-05 23.0 2.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TF_AP-2 PF03299.9 EDO19015.1 - 0.13 11.8 0.1 0.33 10.4 0.0 1.6 2 0 0 2 2 2 0 Transcription factor AP-2 CTV_P23 PF04808.7 EDO19016.1 - 0.02 14.2 0.6 0.033 13.5 0.4 1.4 1 0 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein CENP-Q PF13094.1 EDO19016.1 - 9.1 6.2 23.2 0.039 13.9 6.9 3.0 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit LsmAD PF06741.8 EDO19017.1 - 1.8e-31 108.0 0.7 1.8e-31 108.0 0.5 3.2 3 0 0 3 3 3 1 LsmAD domain SM-ATX PF14438.1 EDO19017.1 - 1e-16 60.6 0.1 3.9e-16 58.7 0.1 2.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 EDO19017.1 - 0.001 18.8 1.8 0.0015 18.2 0.2 2.2 2 0 0 2 2 2 1 Scd6-like Sm domain AATase PF07247.7 EDO19018.1 - 9.5e-152 505.8 9.3 1.1e-151 505.7 6.4 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase SE PF08491.5 EDO19019.1 - 4.1e-115 383.3 0.0 5.4e-115 382.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EDO19019.1 - 8.4e-12 44.8 0.0 1.8e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EDO19019.1 - 1.2e-06 27.7 0.0 8.7e-06 24.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO19019.1 - 0.00049 20.0 0.1 0.00097 19.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EDO19019.1 - 0.00062 20.1 0.7 0.0012 19.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EDO19019.1 - 0.00098 18.0 0.5 0.0039 16.0 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain GDI PF00996.13 EDO19019.1 - 0.0011 17.3 0.1 0.0023 16.3 0.0 1.5 2 0 0 2 2 2 1 GDP dissociation inhibitor Thi4 PF01946.12 EDO19019.1 - 0.0021 17.2 0.0 0.0041 16.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 EDO19019.1 - 0.0039 16.8 0.1 0.0069 16.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EDO19019.1 - 0.0071 16.2 0.5 0.022 14.6 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EDO19019.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EDO19019.1 - 0.037 13.1 1.7 0.043 12.9 0.4 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 EDO19019.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EDO19019.1 - 0.11 11.3 0.3 0.4 9.4 0.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EDO19019.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EDO19019.1 - 0.18 11.1 0.4 0.46 9.8 0.1 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.7 EDO19019.1 - 0.19 10.6 0.9 0.89 8.4 0.1 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein HI0933_like PF03486.9 EDO19019.1 - 0.19 10.1 0.1 0.49 8.8 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein CBP4 PF07960.6 EDO19020.1 - 1.1e-53 180.2 7.1 1.2e-53 180.0 4.9 1.0 1 0 0 1 1 1 1 CBP4 AIP3 PF03915.8 EDO19020.1 - 0.0081 15.1 4.2 0.0098 14.8 2.9 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 DUF600 PF04634.7 EDO19020.1 - 0.018 15.0 0.1 0.06 13.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF600 DUF342 PF03961.8 EDO19020.1 - 0.037 12.4 1.3 0.045 12.1 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UPF0449 PF15136.1 EDO19020.1 - 0.051 13.7 2.3 0.059 13.5 0.9 1.6 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 OmpH PF03938.9 EDO19020.1 - 1.2 9.0 11.5 1.7 8.6 8.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Atg14 PF10186.4 EDO19020.1 - 1.8 7.4 7.6 2.3 7.0 5.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YgaB PF14182.1 EDO19020.1 - 4.6 7.5 15.2 2 8.6 4.9 2.2 1 1 1 2 2 2 0 YgaB-like protein CENP-H PF05837.7 EDO19020.1 - 9.3 6.4 11.1 2.3 8.4 2.9 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) UCR_UQCRX_QCR9 PF05365.7 EDO19021.1 - 3.7e-26 90.5 1.4 4.2e-26 90.3 1.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.15 EDO19022.1 - 1.6e-18 66.1 13.0 1.6e-18 66.1 9.0 2.8 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EDO19022.1 - 2.9e-07 30.1 0.0 7.5e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 EDO19022.1 - 0.0025 17.6 0.6 0.0025 17.6 0.4 3.6 3 0 0 3 3 3 1 Ring finger domain HlyIII PF03006.15 EDO19023.1 - 1.2e-58 198.1 17.2 1.5e-58 197.7 11.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related SBDS PF01172.13 EDO19024.1 - 3.5e-34 116.4 1.8 5.5e-34 115.8 1.3 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 EDO19024.1 - 1.2e-32 112.2 0.8 1.2e-32 112.2 0.6 1.6 2 0 0 2 2 2 1 SBDS protein C-terminal domain chaperone_DMP PF10448.4 EDO19025.1 - 2.3e-45 154.0 3.7 2.5e-45 153.8 2.6 1.0 1 0 0 1 1 1 1 20S proteasome chaperone Abhydro_lipase PF04083.11 EDO19026.1 - 3.9e-17 61.3 0.0 7.2e-17 60.5 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EDO19026.1 - 4.4e-08 33.2 0.0 7.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO19026.1 - 9.9e-05 22.0 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EDO19026.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family WD40 PF00400.27 EDO19027.1 - 2e-34 116.2 6.3 3.2e-09 36.2 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 EDO19027.1 - 3.1e-29 100.8 15.3 3.1e-29 100.8 10.6 2.4 2 0 0 2 2 2 1 Sof1-like domain BBS2_Mid PF14783.1 EDO19027.1 - 0.0015 18.2 0.5 0.023 14.4 0.0 3.2 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region NIF PF03031.13 EDO19028.1 - 8.5e-51 171.7 0.1 8.5e-51 171.7 0.1 2.2 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Serglycin PF04360.7 EDO19028.1 - 0.068 12.9 8.2 0.064 12.9 3.9 2.2 1 1 1 2 2 2 0 Serglycin NPCC PF08058.6 EDO19029.1 - 2.3e-44 150.7 6.6 4.3e-44 149.8 4.6 1.5 1 0 0 1 1 1 1 Nuclear pore complex component PNP_UDP_1 PF01048.15 EDO19030.1 - 3.5e-32 111.2 0.0 4.7e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily COX17 PF05051.8 EDO19031.1 - 2.6e-20 72.1 7.7 3.3e-20 71.8 5.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.8 EDO19031.1 - 0.00035 20.3 1.5 0.00061 19.6 1.0 1.5 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EDO19031.1 - 0.0072 16.0 7.7 0.029 14.1 0.1 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Siva PF05458.7 EDO19031.1 - 0.27 10.8 2.7 0.3 10.6 1.9 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) DUF2404 PF10296.4 EDO19033.1 - 8.2e-06 25.8 0.1 9.6e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF2515 PF10720.4 EDO19033.1 - 0.033 13.0 0.4 0.058 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2515) DUF1628 PF07790.6 EDO19033.1 - 0.14 12.9 0.0 0.82 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) Ribophorin_I PF04597.9 EDO19034.1 - 7.9e-137 456.2 8.1 9e-137 456.1 5.6 1.0 1 0 0 1 1 1 1 Ribophorin I Sfi1_C PF10638.4 EDO19035.1 - 6.9e-40 135.8 1.6 6.9e-40 135.8 1.1 3.2 4 0 0 4 4 4 1 Spindle body associated protein C-terminus Sfi1 PF08457.5 EDO19035.1 - 7.1e-19 67.6 73.2 3e-17 62.2 45.5 2.7 1 1 1 2 2 2 2 Sfi1 spindle body protein Proteasome PF00227.21 EDO19036.1 - 3.1e-49 166.8 0.9 3.5e-49 166.6 0.6 1.0 1 0 0 1 1 1 1 Proteasome subunit Dynamin_M PF01031.15 EDO19037.1 - 3.6e-111 370.6 0.0 6.1e-111 369.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EDO19037.1 - 5.7e-55 185.6 0.1 7.7e-54 182.0 0.0 2.8 2 1 0 2 2 2 1 Dynamin family GED PF02212.13 EDO19037.1 - 4.5e-28 96.9 3.8 1.5e-27 95.2 2.6 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EDO19037.1 - 0.00054 19.9 1.0 0.59 10.1 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EDO19037.1 - 0.0038 17.7 0.1 0.047 14.1 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein SH3_1 PF00018.23 EDO19038.1 - 1.3e-13 50.0 0.0 2.9e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO19038.1 - 1.1e-11 44.1 0.1 3.2e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDO19038.1 - 6.7e-07 28.7 0.0 1.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3134 PF11332.3 EDO19038.1 - 0.48 10.5 0.1 0.48 10.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3134) DUF4611 PF15387.1 EDO19038.1 - 2 8.5 20.5 0.19 11.9 1.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4611) NOA36 PF06524.7 EDO19038.1 - 2.4 7.3 13.5 0.077 12.2 2.3 2.2 2 0 0 2 2 2 0 NOA36 protein Cwf_Cwc_15 PF04889.7 EDO19039.1 - 3.3e-24 85.9 29.8 7.8e-15 55.2 15.6 2.5 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein Nop53 PF07767.6 EDO19039.1 - 0.05 12.5 13.1 0.043 12.7 8.5 1.3 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Daxx PF03344.10 EDO19039.1 - 0.069 11.6 12.3 0.08 11.4 8.5 1.1 1 0 0 1 1 1 0 Daxx Family PPP4R2 PF09184.6 EDO19039.1 - 0.075 12.5 11.2 0.14 11.6 7.8 1.4 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.8 EDO19039.1 - 0.093 12.3 11.0 0.13 11.8 7.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM220 PF15487.1 EDO19039.1 - 0.15 11.3 2.7 0.25 10.6 1.9 1.3 1 0 0 1 1 1 0 FAM220 family Nucleoplasmin PF03066.10 EDO19039.1 - 0.24 10.9 13.3 0.36 10.3 9.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin HABP4_PAI-RBP1 PF04774.10 EDO19039.1 - 0.51 10.8 11.8 0.87 10.1 8.2 1.6 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family DNA_pol_phi PF04931.8 EDO19039.1 - 2.7 5.6 17.4 3.2 5.4 12.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Autophagy_N PF03986.8 EDO19039.1 - 3.3 7.4 9.5 0.42 10.3 3.6 1.6 2 0 0 2 2 2 0 Autophagocytosis associated protein (Atg3), N-terminal domain CDC45 PF02724.9 EDO19039.1 - 5.7 4.8 12.8 6 4.7 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein LAT PF15234.1 EDO19039.1 - 6.1 6.2 8.6 9.4 5.6 6.0 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells Myc_N PF01056.13 EDO19039.1 - 8.9 5.3 12.8 8 5.5 8.2 1.5 1 1 0 1 1 1 0 Myc amino-terminal region Rho_GDI PF02115.12 EDO19041.1 - 1.8e-63 213.6 0.8 2.1e-63 213.3 0.6 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 EDO19042.1 - 1.1e-39 135.8 0.5 1.5e-39 135.4 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mit_KHE1 PF10173.4 EDO19043.1 - 8.5e-49 165.9 1.0 1.1e-48 165.5 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF793 PF05633.6 EDO19043.1 - 0.017 13.8 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF793) MARVEL PF01284.18 EDO19044.1 - 0.04 13.7 2.2 0.078 12.7 1.5 1.5 1 0 0 1 1 1 0 Membrane-associating domain Cullin PF00888.17 EDO19045.1 - 1.4e-56 192.3 10.1 1.7e-56 192.0 7.0 1.0 1 0 0 1 1 1 1 Cullin family Cullin PF00888.17 EDO19046.1 - 3.1e-88 296.8 0.8 3.1e-88 296.8 0.6 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EDO19046.1 - 4.4e-25 87.2 3.2 9.3e-25 86.2 0.9 2.5 2 1 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 EDO19046.1 - 0.032 14.3 0.1 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 Penicillinase repressor HMGL-like PF00682.14 EDO19047.1 - 1.3e-74 250.8 0.1 3.2e-74 249.5 0.2 1.6 2 0 0 2 2 2 1 HMGL-like Ribosomal_60s PF00428.14 EDO19048.1 - 2.8e-23 82.0 11.8 3.3e-23 81.8 8.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 EDO19048.1 - 0.023 14.2 0.5 0.028 14.0 0.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DSBA PF01323.15 EDO19048.1 - 0.32 10.5 1.3 0.39 10.2 0.9 1.1 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Na_Ca_ex PF01699.19 EDO19049.1 - 1.9e-49 166.8 30.9 1e-24 86.7 6.0 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YWFCY PF14293.1 EDO19049.1 - 0.015 15.1 0.5 0.15 11.9 0.0 2.5 2 0 0 2 2 2 0 YWFCY protein Neurensin PF14927.1 EDO19049.1 - 0.63 9.4 4.5 1.2 8.4 0.1 3.0 2 1 1 3 3 3 0 Neurensin Cyclin_N PF00134.18 EDO19050.1 - 6.7e-14 51.5 0.0 1.4e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EDO19050.1 - 2.8e-08 34.2 0.0 2.8e-08 34.2 0.0 2.3 2 1 0 2 2 2 1 Cyclin AAA PF00004.24 EDO19051.1 - 6e-98 324.1 0.0 4.9e-48 162.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EDO19051.1 - 1.6e-19 69.6 1.4 3.2e-19 68.6 0.5 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_5 PF07728.9 EDO19051.1 - 1.5e-13 50.6 0.4 2e-06 27.6 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EDO19051.1 - 1.7e-13 50.1 0.0 1.4e-05 24.2 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EDO19051.1 - 1.8e-13 50.7 0.0 2.8e-07 30.6 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EDO19051.1 - 5e-12 46.1 0.0 0.00043 20.3 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_33 PF13671.1 EDO19051.1 - 1.8e-11 44.0 0.0 7.2e-06 25.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EDO19051.1 - 3.4e-11 44.0 0.1 0.0011 19.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EDO19051.1 - 5.6e-11 42.6 0.8 0.0011 19.0 0.1 3.9 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.8 EDO19051.1 - 2.9e-09 36.1 0.0 0.0012 17.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus CDC48_2 PF02933.12 EDO19051.1 - 1.9e-08 33.8 0.0 4.9e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EDO19051.1 - 3.6e-08 33.3 0.0 0.004 17.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EDO19051.1 - 9.3e-08 31.6 0.1 0.0071 15.7 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EDO19051.1 - 2.1e-07 31.0 0.0 0.011 15.9 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 EDO19051.1 - 2.8e-07 30.1 1.2 0.025 14.3 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 EDO19051.1 - 3.7e-07 29.7 6.0 0.013 14.8 0.4 4.1 2 2 1 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EDO19051.1 - 3.9e-07 29.4 0.5 0.03 13.4 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EDO19051.1 - 6.8e-07 28.5 0.1 0.011 14.9 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin KaiC PF06745.8 EDO19051.1 - 1.1e-06 27.8 0.8 0.42 9.6 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_24 PF13479.1 EDO19051.1 - 2.1e-06 27.4 0.1 0.11 12.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.22 EDO19051.1 - 6.5e-06 26.4 0.0 0.046 14.0 0.0 3.9 3 1 0 3 3 3 1 ABC transporter ResIII PF04851.10 EDO19051.1 - 7.3e-06 25.9 0.3 0.01 15.6 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EDO19051.1 - 1.1e-05 25.4 0.0 0.24 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EDO19051.1 - 1.2e-05 24.8 0.1 0.14 11.6 0.0 3.5 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 EDO19051.1 - 1.4e-05 25.4 0.0 0.19 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 EDO19051.1 - 2.3e-05 24.1 0.3 0.00035 20.3 0.1 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Parvo_NS1 PF01057.12 EDO19051.1 - 2.7e-05 23.2 0.1 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.11 EDO19051.1 - 3e-05 23.3 0.6 0.11 11.6 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 EDO19051.1 - 4.2e-05 23.6 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_11 PF13086.1 EDO19051.1 - 5.6e-05 22.8 0.0 0.25 10.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.8 EDO19051.1 - 9.4e-05 21.4 0.0 0.13 11.1 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.6 EDO19051.1 - 0.00012 21.7 0.0 0.65 9.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EDO19051.1 - 0.00012 21.8 0.1 0.68 9.5 0.0 3.8 2 2 1 3 3 3 1 Archaeal ATPase NACHT PF05729.7 EDO19051.1 - 0.00022 20.9 0.1 1.6 8.3 0.0 3.4 3 0 0 3 3 3 1 NACHT domain Bac_DnaA PF00308.13 EDO19051.1 - 0.00025 20.7 0.0 0.51 9.9 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein DUF2075 PF09848.4 EDO19051.1 - 0.0005 19.1 0.0 0.68 8.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EDO19051.1 - 0.00056 19.5 0.0 1.6 8.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EDO19051.1 - 0.0055 15.6 0.1 1.7 7.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain IPT PF01745.11 EDO19051.1 - 0.014 14.5 0.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 EDO19051.1 - 0.017 14.1 0.2 1.7 7.5 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain NTPase_1 PF03266.10 EDO19051.1 - 0.019 14.6 3.2 3.3 7.3 0.0 4.4 5 0 0 5 5 5 0 NTPase Zot PF05707.7 EDO19051.1 - 0.027 13.9 0.3 5.6 6.3 0.1 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) SKI PF01202.17 EDO19051.1 - 0.052 13.4 0.0 4.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 EDO19051.1 - 0.054 13.1 0.1 6.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EDO19051.1 - 0.066 12.1 0.0 2.4 6.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein UFD1 PF03152.9 EDO19051.1 - 0.084 12.0 0.0 0.44 9.6 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 eIF-1a PF01176.14 EDO19051.1 - 0.096 12.1 0.6 1.9 7.9 0.1 2.9 2 1 1 3 3 3 0 Translation initiation factor 1A / IF-1 DEAD PF00270.24 EDO19051.1 - 0.16 11.4 0.2 24 4.3 0.0 3.3 3 1 0 4 4 3 0 DEAD/DEAH box helicase Arf PF00025.16 EDO19052.1 - 3.1e-78 260.9 0.0 3.6e-78 260.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EDO19052.1 - 2.6e-14 52.9 0.0 2.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EDO19052.1 - 6.2e-14 51.6 0.0 7.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EDO19052.1 - 4.4e-11 42.1 0.5 4.8e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EDO19052.1 - 8.8e-11 41.3 0.0 1.1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EDO19052.1 - 1.5e-10 41.6 0.0 2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EDO19052.1 - 8.4e-06 25.7 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EDO19052.1 - 0.0057 16.1 0.0 0.027 13.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 EDO19052.1 - 0.006 16.0 0.2 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EDO19052.1 - 0.0069 16.2 0.1 0.011 15.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EDO19052.1 - 0.021 14.5 0.5 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 EDO19052.1 - 0.032 14.5 0.1 0.059 13.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.13 EDO19052.1 - 0.042 12.9 0.1 0.061 12.3 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DBD_Tnp_Mut PF03108.10 EDO19052.1 - 0.071 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase cobW PF02492.14 EDO19052.1 - 0.075 12.4 0.1 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Prenyltransf PF01255.14 EDO19053.1 - 0.0044 16.1 0.0 0.071 12.2 0.0 2.2 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Med28 PF11594.3 EDO19053.1 - 0.08 13.1 0.0 1.3 9.3 0.0 2.5 2 1 1 3 3 3 0 Mediator complex subunit 28 RNase_H2_suC PF08615.6 EDO19054.1 - 9.2e-17 61.1 0.0 1.2e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DUF2665 PF11654.3 EDO19055.1 - 7.8e-25 86.1 0.3 8.9e-25 86.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) CTD_bind PF04818.8 EDO19056.1 - 3.3e-05 24.0 2.6 0.00031 20.9 1.2 3.4 2 0 0 2 2 2 1 RNA polymerase II-binding domain. HEAT PF02985.17 EDO19056.1 - 0.054 13.5 0.1 2.4 8.4 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat Endonuclease_NS PF01223.18 EDO19057.1 - 1.2e-46 159.0 0.0 1.5e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Pex2_Pex12 PF04757.9 EDO19060.1 - 5.8e-21 74.9 16.2 8.5e-21 74.4 11.2 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Endonuc-BglII PF09195.6 EDO19060.1 - 0.05 13.0 0.2 0.084 12.3 0.2 1.3 1 0 0 1 1 1 0 Restriction endonuclease BglII DUF1015 PF06245.6 EDO19060.1 - 0.14 10.6 0.0 0.19 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) zf-C3HC4_2 PF13923.1 EDO19060.1 - 0.44 10.6 9.4 1 9.4 6.5 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.22 EDO19061.1 - 3.8e-58 193.1 0.1 3.8e-19 68.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SUI1 PF01253.17 EDO19062.1 - 2.6e-28 97.6 2.2 3.4e-28 97.2 1.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cir_N PF10197.4 EDO19063.1 - 3.6e-12 46.1 9.4 7.7e-12 45.0 6.5 1.6 1 0 0 1 1 1 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.3 EDO19063.1 - 9e-12 45.2 4.0 9e-12 45.2 2.8 1.8 1 1 1 2 2 2 1 Pre-mRNA splicing factor NAP PF00956.13 EDO19064.1 - 3.7e-22 78.6 7.0 5.7e-22 78.0 4.9 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Vpu PF00558.14 EDO19064.1 - 2.1 7.9 8.5 3.2 7.3 0.1 2.5 2 0 0 2 2 2 0 Vpu protein tRNA-synt_1e PF01406.14 EDO19065.1 - 3.5e-141 469.6 4.6 3.5e-141 469.6 3.2 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EDO19065.1 - 4.7e-06 25.5 0.3 4.7e-06 25.5 0.2 3.3 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EDO19065.1 - 5e-05 21.5 0.0 5e-05 21.5 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) LCAT PF02450.10 EDO19066.1 - 2.2e-08 33.5 0.8 2.7e-07 29.9 0.6 2.1 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EDO19066.1 - 3.7e-08 33.2 0.0 9.4e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EDO19066.1 - 8.2e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EDO19066.1 - 9.1e-05 22.1 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 EDO19066.1 - 0.00018 20.9 0.1 0.00052 19.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EDO19066.1 - 0.00034 20.3 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EDO19066.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_8 PF06259.7 EDO19066.1 - 0.04 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase zf-CSL PF05207.8 EDO19067.1 - 6.5e-17 60.7 0.7 1e-16 60.1 0.5 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EDO19067.1 - 6.5e-14 51.4 0.1 1.1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain zinc_ribbon_4 PF13717.1 EDO19067.1 - 0.047 13.3 0.6 7 6.4 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EDO19067.1 - 0.084 12.4 0.9 8.9 5.9 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-CW PF07496.10 EDO19067.1 - 0.097 12.3 0.1 0.27 10.9 0.1 1.8 1 0 0 1 1 1 0 CW-type Zinc Finger E7 PF00527.13 EDO19067.1 - 0.31 11.2 2.7 0.88 9.7 1.3 2.1 2 1 0 2 2 2 0 E7 protein, Early protein RNA_pol_I_A49 PF06870.7 EDO19068.1 - 4.5e-146 486.3 0.3 5.1e-146 486.1 0.2 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor AAA_23 PF13476.1 EDO19069.1 - 4.4e-22 79.4 28.5 4.4e-22 79.4 19.8 7.9 2 1 2 5 5 5 1 AAA domain Rad50_zn_hook PF04423.9 EDO19069.1 - 7e-16 57.4 1.3 7e-16 57.4 0.9 6.9 7 0 0 7 7 7 1 Rad50 zinc hook motif AAA_13 PF13166.1 EDO19069.1 - 5.2e-12 45.0 148.3 3.2e-05 22.6 0.0 7.0 3 1 4 7 7 7 5 AAA domain SbcCD_C PF13558.1 EDO19069.1 - 2e-11 43.6 0.0 6.4e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EDO19069.1 - 1.9e-08 34.6 12.8 2.2e-05 24.5 7.1 6.4 2 1 4 7 7 7 2 AAA domain SMC_N PF02463.14 EDO19069.1 - 1.4e-07 30.9 0.1 1.4e-07 30.9 0.1 3.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDO19069.1 - 0.00029 20.3 0.0 0.00081 18.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EDO19069.1 - 0.0012 17.9 34.7 0.0012 17.9 24.1 5.6 1 1 4 5 5 5 2 AAA ATPase domain TMF_TATA_bd PF12325.3 EDO19069.1 - 0.0036 17.0 13.6 0.0036 17.0 9.4 10.1 6 4 2 10 10 10 1 TATA element modulatory factor 1 TATA binding AAA_19 PF13245.1 EDO19069.1 - 0.099 12.4 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain rve PF00665.21 EDO19070.1 - 1.1e-17 64.2 0.0 2.6e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain C2 PF00168.25 EDO19070.1 - 0.021 14.6 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 C2 domain DUF484 PF04340.7 EDO19071.1 - 0.034 13.6 2.6 0.056 12.9 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF484 FCH PF00611.18 EDO19071.1 - 0.043 13.9 5.6 0.11 12.7 3.9 1.8 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF2340 PF10209.4 EDO19071.1 - 0.066 13.3 3.7 0.14 12.3 2.6 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2340) BpuSI_N PF15516.1 EDO19071.1 - 0.079 12.6 0.6 8.9 5.9 0.1 2.4 1 1 1 2 2 2 0 BpuSI N-terminal domain V_ATPase_I PF01496.14 EDO19071.1 - 0.14 10.0 10.0 0.19 9.5 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 EDO19071.1 - 1.8 8.9 11.5 0.39 11.0 4.2 2.3 1 1 0 2 2 2 0 Snapin/Pallidin RRM_1 PF00076.17 EDO19072.1 - 1.1e-05 24.9 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO19072.1 - 0.00055 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EDO19072.1 - 0.11 12.7 0.0 0.38 11.0 0.0 2.0 1 0 0 1 1 1 0 RNA polymerase II-binding domain. MRP-L46 PF11788.3 EDO19073.1 - 7.6e-38 129.5 0.0 1.2e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 WD40 PF00400.27 EDO19074.1 - 9.7e-16 56.9 15.4 1.1e-05 25.0 0.0 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat RTC4 PF14474.1 EDO19075.1 - 1.9e-34 118.2 0.0 1.8e-33 115.1 0.0 2.2 2 0 0 2 2 2 1 RTC4-like domain GOLD_2 PF13897.1 EDO19075.1 - 1.9 8.7 4.5 0.52 10.5 0.2 2.0 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking Mak16 PF04874.9 EDO19075.1 - 5.1 7.2 9.0 1.4 9.0 0.7 2.6 2 0 0 2 2 2 0 Mak16 protein C-terminal region zf-CCHC PF00098.18 EDO19076.1 - 6.7e-53 174.2 50.8 1.2e-08 34.5 0.7 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EDO19076.1 - 1.2e-11 44.1 43.5 0.016 14.8 1.0 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EDO19076.1 - 1.4e-05 24.7 50.7 0.26 11.0 1.0 7.1 2 2 4 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 EDO19076.1 - 0.0056 16.1 46.3 0.27 10.7 0.6 7.1 2 2 5 7 7 7 4 Zinc knuckle zf-CCHC_6 PF15288.1 EDO19076.1 - 0.056 13.1 2.4 0.056 13.1 1.6 6.9 5 2 2 7 7 7 0 Zinc knuckle zf-RING_3 PF14369.1 EDO19076.1 - 1 9.4 29.9 3 7.9 0.6 6.0 3 3 1 5 5 5 0 zinc-finger Pterin_bind PF00809.17 EDO19077.1 - 6.4e-43 146.5 0.5 1.9e-42 145.0 0.1 2.0 2 1 0 2 2 2 1 Pterin binding enzyme FolB PF02152.13 EDO19077.1 - 1.4e-40 138.0 0.2 1.2e-19 70.5 0.4 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.15 EDO19077.1 - 1.9e-39 134.2 0.0 4.1e-39 133.2 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FAD_binding_3 PF01494.14 EDO19078.1 - 3.1e-18 65.9 2.0 2e-12 46.8 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EDO19078.1 - 0.00027 20.0 0.1 0.014 14.3 0.1 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 EDO19078.1 - 0.007 15.3 0.1 0.049 12.5 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO19078.1 - 0.013 15.5 0.2 0.029 14.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EDO19078.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EDO19078.1 - 0.025 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.19 EDO19078.1 - 0.034 13.0 0.8 0.051 12.4 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EDO19078.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EDO19078.1 - 0.1 11.6 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EDO19078.1 - 0.11 11.0 0.1 0.87 8.1 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.2 EDO19078.1 - 0.14 11.1 0.5 0.26 10.3 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EDO19078.1 - 0.14 10.5 0.4 0.2 10.0 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein RRM_1 PF00076.17 EDO19079.1 - 6.7e-15 54.4 0.1 1.9e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO19079.1 - 8.6e-13 48.0 0.1 3.2e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 EDO19079.1 - 2.8e-10 40.6 0.1 3.9e-10 40.1 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_5 PF13893.1 EDO19079.1 - 2.6e-08 33.6 0.1 6.5e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF676 PF05057.9 EDO19080.1 - 6.7e-07 28.8 0.2 1.4e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EDO19080.1 - 8e-05 22.3 0.0 0.00018 21.1 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 EDO19080.1 - 0.00026 20.6 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3989 PF13150.1 EDO19080.1 - 0.0014 17.9 0.0 0.0032 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3989) DUF915 PF06028.6 EDO19080.1 - 0.0023 17.0 0.0 0.019 14.0 0.0 2.3 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 EDO19080.1 - 0.048 13.4 0.0 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EDO19080.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peripla_BP_4 PF13407.1 EDO19080.1 - 0.16 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain KH_dom-like PF14714.1 EDO19081.1 - 0.083 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal PTB PF08416.8 EDO19081.1 - 0.11 12.3 0.2 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotyrosine-binding domain DNA_pol3_a_NI PF14480.1 EDO19081.1 - 0.27 10.8 2.6 2 8.1 1.3 2.5 2 1 0 2 2 2 0 DNA polymerase III polC-type N-terminus I Dsl1_N PF11988.3 EDO19082.1 - 4.2e-142 473.2 27.5 6.3e-142 472.6 19.0 1.3 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 N terminal Dsl1_C PF11989.3 EDO19082.1 - 2.4e-141 470.0 15.7 2.4e-141 470.0 10.9 2.4 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal HMA PF00403.21 EDO19083.1 - 1.4e-11 44.3 0.2 1.6e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.9 EDO19083.1 - 0.08 12.7 0.1 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Yae1_N PF09811.4 EDO19084.1 - 9e-14 50.7 3.0 9e-14 50.7 2.1 1.5 2 0 0 2 2 2 1 Essential protein Yae1, N terminal NIF PF03031.13 EDO19084.1 - 0.0064 16.1 0.2 0.0098 15.5 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PNK3P PF08645.6 EDO19084.1 - 0.081 12.3 0.4 0.18 11.2 0.1 1.6 1 1 1 2 2 2 0 Polynucleotide kinase 3 phosphatase GYF PF02213.11 EDO19085.1 - 6e-11 41.7 3.0 1.2e-10 40.7 2.1 1.6 1 0 0 1 1 1 1 GYF domain ORC5_C PF14630.1 EDO19086.1 - 8.5e-66 222.1 0.4 1.2e-65 221.7 0.3 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.1 EDO19086.1 - 2.5e-09 37.3 0.0 5.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO19086.1 - 1.2e-07 31.8 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.10 EDO19086.1 - 1.3e-06 28.3 0.0 3.1e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EDO19086.1 - 0.00028 20.6 0.2 0.00062 19.5 0.1 1.5 1 0 0 1 1 1 1 Archaeal ATPase CRAL_TRIO_2 PF13716.1 EDO19086.1 - 0.00038 20.3 0.5 0.0014 18.5 0.2 1.9 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain AAA_14 PF13173.1 EDO19086.1 - 0.0068 16.2 1.2 0.055 13.3 0.8 2.4 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EDO19086.1 - 0.0084 15.1 2.0 1.6 7.6 0.3 2.3 1 1 1 2 2 2 2 KAP family P-loop domain AAA_17 PF13207.1 EDO19086.1 - 0.013 16.3 0.0 0.037 14.8 0.0 2.0 2 1 0 2 2 1 0 AAA domain NB-ARC PF00931.17 EDO19086.1 - 0.028 13.2 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EDO19086.1 - 0.055 13.1 5.2 0.93 9.1 3.6 2.3 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EDO19086.1 - 0.084 13.1 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EDO19086.1 - 0.2 11.0 0.5 0.62 9.4 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF1744 PF08490.7 EDO19087.1 - 1.9e-145 484.3 9.0 3.1e-145 483.7 6.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EDO19087.1 - 1.7e-67 227.6 5.2 4.3e-67 226.2 3.6 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EDO19087.1 - 3.2e-24 85.5 7.0 1.5e-23 83.3 2.0 2.8 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EDO19087.1 - 7e-07 28.9 0.9 6.5e-06 25.8 0.6 2.5 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB YIF1 PF03878.10 EDO19088.1 - 3.3e-74 249.0 10.7 4.1e-74 248.7 7.4 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EDO19088.1 - 0.11 12.0 12.6 0.15 11.5 8.1 1.9 1 1 0 1 1 1 0 Yip1 domain Med15 PF09606.5 EDO19088.1 - 3.4 5.7 20.8 4.1 5.4 14.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DnaJ PF00226.26 EDO19089.1 - 1.4e-15 56.7 0.3 3.3e-15 55.5 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain CRAL_TRIO PF00650.15 EDO19090.1 - 8e-41 139.1 0.0 1.2e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EDO19090.1 - 1.8e-11 44.0 0.8 4.3e-11 42.7 0.6 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EDO19090.1 - 0.00015 21.6 0.0 0.00027 20.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2422 PF10337.4 EDO19091.1 - 3.9e-48 164.3 12.0 1.1e-46 159.6 0.0 3.2 3 0 0 3 3 3 3 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EDO19091.1 - 1.5e-13 50.7 12.8 1.5e-13 50.7 8.9 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EDO19091.1 - 7e-07 28.2 7.8 5.4e-06 25.3 2.1 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 EDO19091.1 - 0.00022 20.9 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC PF04632.7 EDO19091.1 - 0.76 8.1 9.7 12 4.2 7.7 2.1 3 0 0 3 3 3 0 Fusaric acid resistance protein family UFD1 PF03152.9 EDO19092.1 - 7.1e-72 240.2 0.0 9.4e-72 239.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF912 PF06024.7 EDO19092.1 - 0.076 13.0 1.2 0.084 12.9 0.1 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1232 PF06803.7 EDO19092.1 - 0.18 11.2 0.2 0.31 10.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) TPR_17 PF13431.1 EDO19093.1 - 9.6e-15 53.4 8.6 0.0093 16.0 0.0 6.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EDO19093.1 - 8.4e-14 50.9 22.5 0.0029 17.2 0.0 7.6 6 2 1 8 8 7 5 TPR repeat TPR_2 PF07719.12 EDO19093.1 - 2.1e-13 49.0 19.5 2.4 8.2 0.1 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 EDO19093.1 - 3.1e-13 50.0 9.1 0.0012 19.5 0.0 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EDO19093.1 - 3.1e-11 42.8 7.1 0.14 12.8 0.0 8.5 5 2 4 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDO19093.1 - 6.4e-11 42.4 8.6 0.0068 16.7 0.2 5.8 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EDO19093.1 - 6.9e-11 41.9 18.5 0.012 15.5 0.4 6.9 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 EDO19093.1 - 3.7e-09 35.8 20.3 0.51 10.0 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EDO19093.1 - 2.3e-07 30.5 0.2 0.041 13.7 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO19093.1 - 2.6e-07 30.6 7.2 0.64 10.6 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_20 PF14561.1 EDO19093.1 - 5.5e-06 26.4 0.0 1.6 8.8 0.0 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 EDO19093.1 - 3.8e-05 22.8 2.1 0.35 9.9 0.1 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EDO19093.1 - 0.0041 16.8 11.5 12 5.9 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF3273 PF11677.3 EDO19093.1 - 0.006 15.8 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3273) Alkyl_sulf_dimr PF14863.1 EDO19093.1 - 0.025 14.7 0.1 5.4 7.2 0.0 2.8 3 0 0 3 3 2 0 Alkyl sulfatase dimerisation TPR_10 PF13374.1 EDO19093.1 - 0.032 14.1 7.7 0.036 14.0 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EDO19093.1 - 0.063 13.0 25.0 1 9.2 0.0 7.7 9 1 1 10 10 8 0 Tetratricopeptide repeat Apc5 PF12862.2 EDO19093.1 - 0.75 9.6 6.3 2.2 8.1 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 Ist1 PF03398.9 EDO19094.1 - 8.1e-59 197.7 1.3 1.2e-58 197.1 0.9 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Complex1_51K PF01512.12 EDO19094.1 - 0.12 12.1 0.5 0.2 11.3 0.3 1.3 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Mmp37 PF09139.6 EDO19095.1 - 1.7e-103 346.0 10.8 4e-94 315.3 3.0 2.0 1 1 1 2 2 2 2 Mitochondrial matrix Mmp37 PI3_PI4_kinase PF00454.22 EDO19096.1 - 3.4e-27 95.4 0.0 9.3e-27 94.0 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EDO19096.1 - 2.6e-21 75.0 0.0 7.2e-21 73.6 0.0 1.9 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 EDO19096.1 - 5.1e-07 29.0 1.0 1.3e-06 27.7 0.7 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) AA_permease PF00324.16 EDO19097.1 - 5.6e-134 447.0 48.8 7e-134 446.7 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO19097.1 - 7.5e-32 110.3 56.8 1.2e-31 109.7 39.4 1.3 1 1 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.3 EDO19097.1 - 0.0005 19.4 0.9 0.046 13.1 0.1 2.9 2 0 0 2 2 2 2 Intrinsic membrane protein PufX AA_permease PF00324.16 EDO19098.1 - 3.2e-135 451.1 52.8 4e-135 450.8 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO19098.1 - 1.7e-30 105.9 56.9 2.5e-30 105.3 39.4 1.3 1 0 0 1 1 1 1 Amino acid permease Peptidase_M50 PF02163.17 EDO19098.1 - 0.43 9.5 4.0 15 4.4 2.4 2.9 2 1 0 2 2 2 0 Peptidase family M50 Sec2p PF06428.6 EDO19099.1 - 1.7e-29 101.6 10.1 1.7e-29 101.6 7.0 4.6 4 0 0 4 4 4 1 GDP/GTP exchange factor Sec2p Histone PF00125.19 EDO19099.1 - 0.019 15.0 0.2 0.075 13.1 0.1 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TIMELESS PF04821.9 EDO19100.1 - 1.7e-48 165.2 11.5 1.7e-48 165.2 8.0 2.8 2 1 0 2 2 2 1 Timeless protein Peptidase_S8 PF00082.17 EDO19101.1 - 4.2e-26 91.7 1.9 5.4e-26 91.3 1.3 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EDO19101.1 - 0.0029 18.1 0.0 0.0081 16.7 0.0 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sad1_UNC PF07738.8 EDO19102.1 - 3.4e-35 120.7 0.1 7.2e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.20 EDO19102.1 - 0.0053 16.5 0.3 0.023 14.5 0.0 2.2 2 0 0 2 2 2 1 F5/8 type C domain Nop14 PF04147.7 EDO19103.1 - 0.038 11.9 29.7 0.084 10.7 20.6 1.5 1 0 0 1 1 1 0 Nop14-like family 2-Hacid_dh_C PF02826.14 EDO19104.1 - 4.6e-58 195.3 0.0 7.8e-58 194.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EDO19104.1 - 1e-14 54.1 0.0 1.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EDO19104.1 - 6.1e-07 29.4 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EDO19104.1 - 9e-05 22.5 0.0 0.0003 20.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EDO19104.1 - 0.00011 21.6 0.0 0.00039 19.8 0.0 1.9 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 EDO19104.1 - 0.022 14.5 0.8 0.42 10.4 0.0 2.9 3 0 0 3 3 3 0 ThiF family F420_oxidored PF03807.12 EDO19104.1 - 0.036 14.4 0.0 0.12 12.8 0.0 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AgrD PF05931.6 EDO19104.1 - 0.17 11.5 0.8 0.29 10.7 0.6 1.4 1 0 0 1 1 1 0 Staphylococcal AgrD protein TMEM192 PF14802.1 EDO19105.1 - 0.034 12.9 0.6 0.047 12.5 0.4 1.2 1 0 0 1 1 1 0 TMEM192 family Per1 PF04080.8 EDO19106.1 - 2.2e-96 322.4 18.5 2.8e-96 322.0 12.8 1.1 1 0 0 1 1 1 1 Per1-like Spindle_Spc25 PF08234.7 EDO19107.1 - 1.8e-18 66.2 0.0 5.1e-18 64.8 0.0 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 EDO19107.1 - 3.3e-07 29.2 17.4 4.9e-07 28.7 12.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein HAUS5 PF14817.1 EDO19107.1 - 0.00099 17.7 11.6 0.0013 17.4 8.1 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 AAA_13 PF13166.1 EDO19107.1 - 0.015 13.8 13.4 0.02 13.4 9.3 1.1 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.4 EDO19107.1 - 0.025 14.4 28.8 0.04 13.7 18.5 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EDO19107.1 - 0.043 12.2 20.7 0.059 11.8 14.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CAP_N PF01213.14 EDO19107.1 - 0.055 12.7 6.4 0.023 13.9 2.8 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Sec34 PF04136.10 EDO19107.1 - 0.06 13.0 8.2 0.12 12.0 5.7 1.6 1 0 0 1 1 1 0 Sec34-like family TMCO5 PF14992.1 EDO19107.1 - 0.11 11.5 21.6 0.16 11.0 14.9 1.2 1 0 0 1 1 1 0 TMCO5 family GAS PF13851.1 EDO19107.1 - 0.18 10.9 27.9 0.072 12.2 17.7 1.6 2 1 0 2 2 1 0 Growth-arrest specific micro-tubule binding Baculo_p33 PF05214.7 EDO19107.1 - 0.2 10.9 7.9 2.9 7.1 0.1 2.1 1 1 1 2 2 2 0 Baculovirus P33 Lipoprotein_7 PF01540.11 EDO19107.1 - 0.26 10.2 14.2 0.61 9.0 9.4 1.8 1 1 1 2 2 2 0 Adhesin lipoprotein MCC-bdg_PDZ PF10506.4 EDO19107.1 - 0.29 10.9 10.8 1.3 8.9 1.8 2.5 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Sin3_corepress PF08295.7 EDO19107.1 - 0.29 10.9 11.7 0.13 12.0 3.3 2.6 1 1 1 2 2 2 0 Sin3 family co-repressor Atg14 PF10186.4 EDO19107.1 - 0.33 9.8 21.9 1 8.2 15.1 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EDO19107.1 - 0.54 9.2 23.8 1.6 7.7 15.8 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 EDO19107.1 - 0.66 7.2 19.4 3.8 4.6 13.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TEX12 PF15219.1 EDO19107.1 - 1 9.3 7.2 4.8 7.2 4.6 2.2 2 1 0 2 2 2 0 Testis-expressed 12 DUF2316 PF10078.4 EDO19107.1 - 1.1 9.3 5.7 0.34 10.9 1.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) LMBR1 PF04791.11 EDO19107.1 - 1.3 7.5 5.8 1.3 7.5 4.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0242 PF06785.6 EDO19107.1 - 1.5 7.4 13.3 2.1 6.9 9.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) ADIP PF11559.3 EDO19107.1 - 1.7 8.5 21.9 8 6.3 15.2 2.0 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding SdrG_C_C PF10425.4 EDO19107.1 - 1.7 8.5 6.3 10 6.0 1.1 2.3 2 1 0 2 2 2 0 C-terminus of bacterial fibrinogen-binding adhesin DUF745 PF05335.8 EDO19107.1 - 2.1 7.8 11.4 1.4 8.4 6.7 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF745) GBP_C PF02841.9 EDO19107.1 - 2.3 7.2 22.7 6.2 5.9 15.7 1.6 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain TPR_MLP1_2 PF07926.7 EDO19107.1 - 3.2 7.4 24.1 15 5.3 16.7 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Synaptobrevin PF00957.16 EDO19107.1 - 3.6 7.2 11.8 0.16 11.5 2.9 2.3 1 1 1 2 2 2 0 Synaptobrevin Nsp1_C PF05064.8 EDO19107.1 - 3.7 7.2 17.3 3.5 7.3 3.2 2.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region Seryl_tRNA_N PF02403.17 EDO19107.1 - 3.8 7.5 18.9 11 6.1 12.9 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EDO19107.1 - 3.9 7.0 25.8 45 3.5 17.2 2.7 1 1 1 2 2 2 0 IncA protein Med9 PF07544.8 EDO19107.1 - 5.2 6.8 18.8 0.74 9.5 5.3 3.0 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF1732 PF08340.6 EDO19107.1 - 5.6 6.8 14.1 0.34 10.7 2.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1732) HALZ PF02183.13 EDO19107.1 - 9.2 6.0 12.5 0.24 11.1 1.1 3.2 3 1 0 3 3 3 0 Homeobox associated leucine zipper AAA_23 PF13476.1 EDO19107.1 - 9.6 6.4 22.2 5.2 7.3 13.9 1.5 2 0 0 2 2 2 0 AAA domain Exo_endo_phos PF03372.18 EDO19108.1 - 4.5e-15 56.2 0.0 6.6e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4231 PF14015.1 EDO19108.1 - 0.13 12.2 0.8 0.24 11.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Glyco_transf_28 PF03033.15 EDO19109.1 - 6.8e-28 97.1 0.0 1.1e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 EDO19109.1 - 8e-20 70.1 0.1 5.7e-13 48.1 0.0 3.2 2 0 0 2 2 2 2 GRAM domain UDPGT PF00201.13 EDO19109.1 - 1.1e-12 47.3 0.0 2.7e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 EDO19109.1 - 4.2e-10 39.7 0.2 4.4e-09 36.4 0.2 2.7 2 0 0 2 2 2 1 PH domain Glyco_trans_1_3 PF13528.1 EDO19109.1 - 0.017 14.3 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 1 Abhydrolase_1 PF00561.15 EDO19110.1 - 2.7e-62 210.3 0.0 3.7e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EDO19110.1 - 2.8e-11 43.7 0.0 3.5e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EDO19110.1 - 0.00028 20.6 0.0 0.0099 15.6 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family ABC_membrane PF00664.18 EDO19111.1 - 3.6e-58 197.1 3.1 4.6e-58 196.7 2.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EDO19111.1 - 1.2e-31 109.7 0.0 3.6e-30 105.0 0.0 2.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EDO19111.1 - 2e-07 30.4 1.2 1.7e-05 24.1 0.1 2.4 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EDO19111.1 - 0.00012 22.0 0.0 0.00033 20.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.1 EDO19111.1 - 0.00016 21.7 0.8 0.34 10.8 0.1 2.9 2 1 1 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EDO19111.1 - 0.00026 19.6 0.0 0.00041 19.0 0.0 1.2 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_17 PF13207.1 EDO19111.1 - 0.00029 21.6 0.0 0.00071 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EDO19111.1 - 0.0016 18.7 0.0 0.038 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDO19111.1 - 0.002 17.6 0.0 0.0056 16.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EDO19111.1 - 0.0062 16.4 1.1 0.051 13.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EDO19111.1 - 0.0081 15.3 0.1 0.06 12.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EDO19111.1 - 0.012 15.7 0.2 0.12 12.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EDO19111.1 - 0.027 14.6 0.0 0.42 10.7 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EDO19111.1 - 0.03 13.7 0.1 0.08 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 EDO19111.1 - 0.036 13.8 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Dispanin PF04505.7 EDO19111.1 - 0.037 13.5 0.0 0.84 9.2 0.0 2.4 2 0 0 2 2 2 0 Interferon-induced transmembrane protein Zeta_toxin PF06414.7 EDO19111.1 - 0.04 13.0 0.0 0.083 11.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EDO19111.1 - 0.057 12.8 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EDO19111.1 - 0.067 12.6 0.0 11 5.4 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF1461 PF07314.6 EDO19111.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) MobB PF03205.9 EDO19111.1 - 0.078 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PH PF00169.24 EDO19112.1 - 1.2e-07 31.9 0.1 7.9e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 PH domain zf-C4H2 PF10146.4 EDO19112.1 - 3.6 7.5 8.7 0.54 10.2 2.8 1.9 2 0 0 2 2 2 0 Zinc finger-containing protein EMG1 PF03587.9 EDO19113.1 - 2.2e-77 258.9 0.0 2.6e-77 258.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase LCD1 PF09798.4 EDO19114.1 - 1.5e-177 591.5 46.1 1.8e-177 591.3 32.0 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein Asp-B-Hydro_N PF05279.6 EDO19114.1 - 0.29 10.9 6.8 0.65 9.8 4.7 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2335 PF10097.4 EDO19114.1 - 0.29 10.7 4.8 16 5.2 1.1 3.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) DivIC PF04977.10 EDO19114.1 - 1.2 8.6 12.6 0.34 10.4 1.7 2.8 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 EDO19114.1 - 2.5 7.6 13.5 8.3 5.9 9.4 1.9 1 0 0 1 1 1 0 IncA protein Ribosomal_L37e PF01907.14 EDO19115.1 - 9.1e-28 95.8 12.2 1.5e-27 95.1 8.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EDO19115.1 - 0.00058 19.6 2.0 0.00087 19.0 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EDO19115.1 - 0.017 14.8 0.3 0.023 14.3 0.2 1.3 1 1 0 1 1 1 0 SelR domain C1_1 PF00130.17 EDO19115.1 - 0.042 13.5 2.3 0.064 12.9 1.6 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 EDO19115.1 - 0.046 13.4 3.2 0.068 12.9 2.2 1.2 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_6 PF14599.1 EDO19115.1 - 0.085 12.6 2.1 0.13 12.0 1.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon GATA PF00320.22 EDO19115.1 - 0.09 12.1 6.4 0.49 9.7 0.9 2.4 1 1 1 2 2 2 0 GATA zinc finger GCC2_GCC3 PF07699.8 EDO19115.1 - 0.13 11.8 2.4 0.23 11.0 1.6 1.5 1 0 0 1 1 1 0 GCC2 and GCC3 DUF1258 PF06869.7 EDO19115.1 - 0.14 11.2 0.5 0.14 11.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) C1_3 PF07649.7 EDO19115.1 - 0.22 11.6 2.0 2.2 8.3 0.1 2.2 2 0 0 2 2 2 0 C1-like domain zf-C3HC4_3 PF13920.1 EDO19115.1 - 0.22 11.2 2.6 0.31 10.7 1.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 EDO19115.1 - 0.38 10.0 4.9 0.84 8.9 0.5 2.1 1 1 2 3 3 3 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 EDO19115.1 - 0.91 9.6 4.8 1.4 9.0 3.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO19115.1 - 1.2 8.8 4.9 1.9 8.2 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 EDO19115.1 - 1.5 8.3 5.7 38 3.9 0.2 2.2 1 1 1 2 2 2 0 zinc-ribbon domain DUF2256 PF10013.4 EDO19115.1 - 3.8 7.3 6.4 2.3 8.0 0.7 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FHA PF00498.21 EDO19116.1 - 1.6e-06 28.0 0.0 5.3e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 FHA domain Erp_C PF06780.6 EDO19116.1 - 0.0087 15.9 0.4 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 Erp protein C-terminus DUF605 PF04652.11 EDO19117.1 - 3.6e-32 112.2 2.2 5e-32 111.7 1.5 1.2 1 0 0 1 1 1 1 Vta1 like MT0933_antitox PF14013.1 EDO19117.1 - 0.32 11.1 4.4 0.45 10.6 0.1 2.9 3 0 0 3 3 3 0 MT0933-like antitoxin protein S-AdoMet_synt_C PF02773.11 EDO19118.1 - 5.8e-75 249.5 0.1 9.8e-75 248.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EDO19118.1 - 1.3e-47 160.6 0.0 2.6e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EDO19118.1 - 2.4e-44 149.6 0.1 4.4e-44 148.7 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain PAP2 PF01569.16 EDO19119.1 - 3.2e-23 81.8 1.3 3.7e-23 81.6 0.1 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EDO19119.1 - 0.0015 18.7 5.5 0.0015 18.7 3.8 2.7 4 0 0 4 4 4 1 PAP2 superfamily C-terminal FUSC_2 PF13515.1 EDO19119.1 - 0.014 15.2 1.7 0.014 15.2 1.2 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein-like DUF4149 PF13664.1 EDO19119.1 - 5.1 7.2 0.0 5.1 7.2 0.0 3.5 3 2 1 4 4 4 0 Domain of unknown function (DUF4149) PBP PF01161.15 EDO19120.1 - 2e-32 112.0 0.2 2.5e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PSP1 PF04468.7 EDO19121.1 - 9.3e-37 124.8 0.2 9.3e-37 124.8 0.1 3.1 3 0 0 3 3 3 1 PSP1 C-terminal conserved region Cu-oxidase_2 PF07731.9 EDO19122.1 - 6.8e-28 96.8 2.9 1.3e-25 89.4 0.3 3.1 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EDO19122.1 - 6e-24 84.0 11.1 5.2e-21 74.5 1.3 4.4 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EDO19122.1 - 2.8e-22 79.3 0.1 3e-20 72.7 0.1 3.1 2 1 1 3 3 3 1 Multicopper oxidase Oxidored_FMN PF00724.15 EDO19123.1 - 2.6e-57 194.3 0.0 3.6e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EDO19123.1 - 0.037 12.8 0.0 0.08 11.7 0.0 1.5 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) AA_permease PF00324.16 EDO19124.1 - 1.4e-129 432.6 30.3 1.6e-129 432.3 21.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EDO19124.1 - 2.2e-35 122.0 31.1 2.6e-35 121.7 21.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 EDO19124.1 - 6.4 5.2 7.4 1.2 7.6 0.5 2.8 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) Nitroreductase PF00881.19 EDO19125.1 - 1.2e-07 31.6 0.0 1.4e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF512 PF04459.7 EDO19125.1 - 0.0014 17.6 0.0 0.002 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF512) Nitroreductase PF00881.19 EDO19126.1 - 5.6e-08 32.7 0.0 6.8e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family SKG6 PF08693.5 EDO19127.1 - 7.9e-06 25.0 0.0 1.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EDO19127.1 - 5.5e-05 22.7 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SH3_9 PF14604.1 EDO19127.1 - 0.0006 19.3 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EDO19127.1 - 0.0011 18.3 0.0 0.0022 17.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EDO19127.1 - 0.092 12.2 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Ste50p-SAM PF09235.5 EDO19128.1 - 3.4e-24 84.6 1.4 7.1e-24 83.6 1.0 1.6 1 0 0 1 1 1 1 Ste50p, sterile alpha motif RA PF00788.18 EDO19128.1 - 7.1e-15 55.2 0.6 3.9e-14 52.9 0.0 2.3 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 EDO19128.1 - 0.0098 15.7 0.3 0.03 14.1 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EDO19128.1 - 0.031 14.4 0.0 0.082 13.0 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EDO19128.1 - 0.041 13.6 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Macoilin PF09726.4 EDO19128.1 - 0.68 8.1 9.8 0.85 7.8 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3128 PF11326.3 EDO19129.1 - 4.6e-32 109.9 2.5 5.2e-32 109.8 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) SelR PF01641.13 EDO19130.1 - 2.7e-50 169.2 1.0 3e-50 169.0 0.7 1.0 1 0 0 1 1 1 1 SelR domain zf-H2C2_2 PF13465.1 EDO19130.1 - 0.0071 16.5 3.6 0.44 10.9 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-Di19 PF05605.7 EDO19130.1 - 0.021 14.9 0.8 0.087 12.9 0.1 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HNH_5 PF14279.1 EDO19130.1 - 0.04 13.9 2.0 0.4 10.7 0.2 2.4 2 0 0 2 2 2 0 HNH endonuclease DUF2296 PF10058.4 EDO19130.1 - 0.051 13.3 2.9 2 8.2 0.2 2.5 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Yippee-Mis18 PF03226.9 EDO19130.1 - 0.11 12.5 3.7 0.59 10.2 2.3 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TNFR_c6 PF00020.13 EDO19130.1 - 0.16 12.0 3.6 0.44 10.6 0.4 2.4 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region HECT_2 PF09814.4 EDO19130.1 - 0.23 10.1 1.3 1.9 7.1 0.0 2.0 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GFA PF04828.9 EDO19130.1 - 0.24 11.3 4.5 1.1 9.2 0.3 2.2 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.7 EDO19130.1 - 0.43 9.9 3.0 5.9 6.2 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.2 EDO19130.1 - 0.48 10.2 6.5 1.1 9.0 0.6 2.1 1 1 1 2 2 2 0 Double zinc ribbon Endonuclease_7 PF02945.10 EDO19130.1 - 0.64 9.7 6.2 4.5 7.0 4.3 2.0 1 1 0 1 1 1 0 Recombination endonuclease VII Tnp_zf-ribbon_2 PF13842.1 EDO19130.1 - 0.73 10.2 6.2 1.8 9.0 0.1 2.5 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-Mss51 PF13824.1 EDO19130.1 - 0.93 9.4 3.9 2.7 7.9 0.1 2.8 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 A2L_zn_ribbon PF08792.5 EDO19130.1 - 1.3 8.5 5.5 1.6 8.2 0.0 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-HIT PF04438.11 EDO19130.1 - 2.1 8.0 7.4 1.3 8.7 0.5 2.6 2 0 0 2 2 2 0 HIT zinc finger Glutaredoxin PF00462.19 EDO19131.1 - 1.3e-12 47.5 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 EDO19131.1 - 0.01 15.6 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.1 EDO19131.1 - 0.049 13.2 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.1 EDO19131.1 - 0.13 12.5 0.2 0.31 11.2 0.1 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain La PF05383.12 EDO19133.1 - 5e-21 74.2 0.2 4.8e-20 71.1 0.0 2.4 2 0 0 2 2 2 1 La domain AXH PF08517.7 EDO19133.1 - 0.0023 18.0 0.7 0.0048 17.0 0.0 1.9 2 0 0 2 2 2 1 Ataxin-1 and HBP1 module (AXH) ATG22 PF11700.3 EDO19134.1 - 4.7e-163 543.0 27.9 5.4e-163 542.8 19.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EDO19134.1 - 7.7e-10 38.0 33.1 2.3e-06 26.5 3.6 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily Hexokinase_2 PF03727.11 EDO19135.1 - 1.5e-88 296.0 0.0 2.1e-88 295.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EDO19135.1 - 6.2e-73 244.5 0.0 2.4e-72 242.5 0.0 1.8 2 0 0 2 2 2 1 Hexokinase DUF1700 PF08006.6 EDO19135.1 - 0.31 10.3 0.8 10 5.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) Thioredoxin PF00085.15 EDO19136.1 - 2.1e-57 191.1 1.7 1.8e-31 107.8 0.2 3.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EDO19136.1 - 3.9e-32 111.5 10.2 9.9e-25 87.4 3.3 3.4 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EDO19136.1 - 2.7e-09 36.9 0.1 0.00044 20.2 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO19136.1 - 1e-08 35.3 6.6 0.00011 22.3 0.2 4.4 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EDO19136.1 - 7.7e-07 29.1 6.2 0.011 15.8 0.0 4.3 3 2 0 3 3 3 2 Thioredoxin-like Redoxin PF08534.5 EDO19136.1 - 2.3e-05 23.9 0.1 0.25 10.8 0.0 2.5 2 0 0 2 2 2 2 Redoxin AhpC-TSA PF00578.16 EDO19136.1 - 0.00049 19.7 0.1 0.05 13.2 0.0 2.8 2 0 0 2 2 2 1 AhpC/TSA family FKBP_C PF00254.23 EDO19137.1 - 5.6e-31 106.4 0.0 7e-31 106.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PsaM PF07465.8 EDO19137.1 - 0.01 15.4 0.7 0.017 14.6 0.5 1.4 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) Pmp3 PF01679.12 EDO19138.1 - 1.3e-19 69.5 5.6 1.6e-19 69.3 3.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator ATP_transf PF09830.4 EDO19139.1 - 2.8e-21 75.0 0.0 9e-21 73.4 0.0 1.9 2 0 0 2 2 2 1 ATP adenylyltransferase UCR_14kD PF02271.11 EDO19140.1 - 8e-43 144.4 0.1 9.1e-43 144.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Aldo_ket_red PF00248.16 EDO19141.1 - 5.2e-62 209.2 0.1 6e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ras PF00071.17 EDO19141.1 - 0.042 13.2 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Ras family Flocculin PF00624.13 EDO19142.1 - 1.2e-186 604.4 1428.9 1.4e-12 47.2 8.7 62.4 44 3 18 63 63 63 34 Flocculin repeat Helicase_C PF00271.26 EDO19144.1 - 2.6e-15 56.0 0.0 6.6e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EDO19144.1 - 3.8e-08 32.9 0.0 7.9e-07 28.7 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase PQ-loop PF04193.9 EDO19146.1 - 2.1e-06 27.1 3.3 2.1e-06 27.1 2.3 3.7 4 1 1 5 5 5 2 PQ loop repeat DUF3810 PF12725.2 EDO19146.1 - 6.7 5.5 13.1 2.9 6.7 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Rer1 PF03248.8 EDO19147.1 - 5.8e-75 250.7 7.7 6.8e-75 250.5 5.3 1.0 1 0 0 1 1 1 1 Rer1 family MFS_1 PF07690.11 EDO19147.1 - 0.01 14.5 4.1 0.013 14.2 2.8 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily eRF1_2 PF03464.10 EDO19148.1 - 1.5e-31 109.4 0.4 2.6e-31 108.6 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EDO19148.1 - 1.3e-26 93.0 0.1 3.5e-26 91.6 0.1 1.8 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EDO19148.1 - 2.5e-11 43.2 0.3 4.2e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Peptidase_C16 PF01831.12 EDO19148.1 - 0.024 14.1 0.1 0.41 10.1 0.0 2.3 1 1 1 2 2 2 0 Peptidase C16 family PhosphMutase PF10143.4 EDO19148.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase RsbU_N PF08673.5 EDO19149.1 - 0.065 13.2 0.3 0.17 11.9 0.1 1.7 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain Ribosomal_L32p PF01783.18 EDO19150.1 - 1.3e-11 44.5 6.4 2.2e-11 43.7 4.4 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family Elongin_A PF06881.6 EDO19150.1 - 0.015 15.6 2.1 0.12 12.7 1.1 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A L31 PF09784.4 EDO19150.1 - 1 9.4 4.7 12 6.0 3.3 2.2 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L31 Flavodoxin_1 PF00258.20 EDO19151.1 - 6.1e-10 39.2 0.0 1.2e-09 38.2 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin FMN_red PF03358.10 EDO19151.1 - 7.6e-07 28.7 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EDO19151.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EDO19151.1 - 0.11 12.4 0.1 30 4.5 0.1 2.9 2 1 1 3 3 3 0 Flavodoxin domain Arrestin_C PF02752.17 EDO19152.1 - 0.087 12.9 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Rad21_Rec8_N PF04825.8 EDO19153.1 - 4.4e-17 62.0 0.1 1.6e-16 60.1 0.1 1.9 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Myticin-prepro PF10690.4 EDO19154.1 - 3.6 7.6 12.7 5.3 7.1 8.8 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel rve PF00665.21 EDO19155.1 - 1.7e-07 31.3 0.1 2.3e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Integrase core domain DUF4521 PF15021.1 EDO19155.1 - 0.07 12.7 0.0 0.09 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Pkinase PF00069.20 EDO19156.1 - 8.3e-64 215.2 0.0 1.4e-63 214.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO19156.1 - 4.2e-26 91.5 0.0 6.2e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO19156.1 - 0.013 14.5 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EDO19156.1 - 0.05 13.3 0.1 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EDO19156.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Macoilin PF09726.4 EDO19156.1 - 3 6.0 19.7 4.3 5.5 13.6 1.1 1 0 0 1 1 1 0 Transmembrane protein BAR PF03114.13 EDO19157.1 - 6.2e-33 114.2 2.7 7.1e-33 114.0 1.9 1.0 1 0 0 1 1 1 1 BAR domain CENP-F_leu_zip PF10473.4 EDO19157.1 - 0.0074 16.1 0.2 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cast PF10174.4 EDO19157.1 - 0.0077 14.3 0.2 0.0081 14.2 0.1 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF2458 PF10454.4 EDO19157.1 - 0.011 15.6 1.2 0.017 15.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF4164 PF13747.1 EDO19157.1 - 0.039 14.0 1.9 0.058 13.5 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Vps5 PF09325.5 EDO19157.1 - 0.11 11.7 1.5 0.23 10.6 1.0 1.6 1 1 0 1 1 1 0 Vps5 C terminal like ABC_tran_2 PF12848.2 EDO19157.1 - 2.8 7.8 6.0 1.2 9.0 2.6 1.5 2 0 0 2 2 2 0 ABC transporter ABC2_membrane PF01061.19 EDO19159.1 - 1.9e-35 121.9 18.3 1.9e-35 121.9 12.7 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EDO19159.1 - 1.9e-27 96.2 0.2 5.4e-27 94.7 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 EDO19159.1 - 0.00016 21.7 0.0 0.00036 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EDO19159.1 - 0.00052 19.4 0.0 0.0036 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EDO19159.1 - 0.0013 17.9 0.1 0.0036 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDO19159.1 - 0.0047 17.7 0.1 0.032 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EDO19159.1 - 0.0071 15.8 0.2 0.04 13.4 0.2 2.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EDO19159.1 - 0.033 14.1 0.7 0.058 13.3 0.5 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EDO19159.1 - 0.046 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EDO19159.1 - 0.084 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EDO19159.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Cytochrom_B562 PF07361.6 EDO19159.1 - 0.19 12.1 0.4 0.36 11.2 0.3 1.3 1 0 0 1 1 1 0 Cytochrome b562 NACHT PF05729.7 EDO19159.1 - 0.32 10.6 1.2 0.69 9.5 0.4 1.9 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EDO19159.1 - 0.33 10.5 1.2 0.52 9.9 0.2 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ODV-E18 PF10717.4 EDO19159.1 - 0.43 10.0 3.1 0.45 9.9 0.2 2.6 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Laminin_EGF PF00053.19 EDO19159.1 - 0.59 10.1 27.9 0.057 13.3 4.4 3.6 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) PGK PF00162.14 EDO19160.1 - 1.3e-151 504.5 0.1 1.5e-151 504.3 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DNA_pol_B_thumb PF14791.1 EDO19161.1 - 7.2e-18 64.0 0.1 7.2e-18 64.0 0.1 2.0 2 0 0 2 2 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EDO19161.1 - 1.1e-16 60.7 0.0 3.7e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.1 EDO19161.1 - 2.5e-10 40.3 0.0 2.1e-09 37.4 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 EDO19161.1 - 3.9e-08 32.7 0.1 1.2e-07 31.2 0.0 1.9 2 0 0 2 2 1 1 Fingers domain of DNA polymerase lambda CDC45 PF02724.9 EDO19161.1 - 7.5e-05 20.9 9.5 0.0001 20.4 6.6 1.1 1 0 0 1 1 1 1 CDC45-like protein Trypan_PARP PF05887.6 EDO19161.1 - 0.00026 20.8 13.0 0.00042 20.1 9.0 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Vfa1 PF08432.5 EDO19161.1 - 0.046 13.7 11.2 0.055 13.5 6.9 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Cdd1 PF11731.3 EDO19161.1 - 0.066 13.1 0.0 16 5.4 0.0 2.7 1 1 1 2 2 2 0 Pathogenicity locus DDHD PF02862.12 EDO19161.1 - 0.082 12.6 8.4 0.15 11.8 5.8 1.4 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 EDO19161.1 - 0.15 11.9 10.6 0.24 11.2 7.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Bud13 PF09736.4 EDO19161.1 - 0.24 11.6 8.5 0.56 10.4 5.9 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2201_N PF13203.1 EDO19161.1 - 0.33 10.0 2.1 0.5 9.4 1.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain NPR3 PF03666.8 EDO19161.1 - 0.44 9.0 14.9 0.084 11.3 8.0 1.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Dsh_C PF12316.3 EDO19161.1 - 0.96 9.5 10.0 0.72 9.9 5.9 1.5 2 0 0 2 2 1 0 Segment polarity protein dishevelled (Dsh) C terminal Adaptin_binding PF10199.4 EDO19161.1 - 1.1 9.4 16.4 2.5 8.3 11.4 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 BUD22 PF09073.5 EDO19161.1 - 1.5 7.8 23.9 2.8 6.9 16.6 1.4 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 EDO19161.1 - 1.5 8.1 19.7 2.3 7.5 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TraH_2 PF06871.6 EDO19161.1 - 2.5 7.4 4.2 5.6 6.3 2.9 1.5 1 0 0 1 1 1 0 TraH_2 Daxx PF03344.10 EDO19161.1 - 3.2 6.1 20.1 4.4 5.6 14.0 1.1 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 EDO19161.1 - 5 6.0 6.2 7 5.5 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.7 EDO19161.1 - 9.5 3.9 25.1 2.6 5.8 15.4 1.4 2 0 0 2 2 2 0 Nop14-like family zf-H2C2_2 PF13465.1 EDO19162.1 - 1.5e-08 34.4 19.3 1.3e-06 28.4 2.4 3.8 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO19162.1 - 2e-05 24.5 11.6 0.0012 19.0 1.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO19162.1 - 2.5e-05 24.3 17.5 0.0028 17.8 2.9 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 EDO19162.1 - 0.041 14.0 0.6 0.041 14.0 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EDO19162.1 - 1.2 8.9 4.4 10 5.9 0.1 3.0 3 0 0 3 3 3 0 zinc-finger of a C2HC-type ATP_bind_3 PF01171.15 EDO19163.1 - 3.3e-19 69.0 0.0 5.7e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EDO19163.1 - 0.00011 22.5 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 EDO19163.1 - 0.0073 14.9 0.0 0.012 14.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase WASH-7_C PF14746.1 EDO19163.1 - 0.047 13.2 0.1 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal MU117 PF15474.1 EDO19163.1 - 0.049 14.1 2.6 0.13 12.7 1.2 2.0 2 0 0 2 2 2 0 Meiotically up-regulated gene family TF_Zn_Ribbon PF08271.7 EDO19163.1 - 0.91 8.8 7.6 8.1 5.8 0.1 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding PX PF00787.19 EDO19164.1 - 3e-13 49.5 0.3 5.9e-13 48.5 0.2 1.5 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EDO19164.1 - 5.8e-10 38.7 7.3 1.8e-09 37.1 5.1 1.8 1 0 0 1 1 1 1 SNARE domain WD40 PF00400.27 EDO19165.1 - 1.1e-16 60.0 15.4 1.1e-08 34.5 0.3 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat IKI3 PF04762.7 EDO19165.1 - 0.0043 14.9 0.0 0.0065 14.3 0.0 1.2 1 0 0 1 1 1 1 IKI3 family Nup160 PF11715.3 EDO19165.1 - 0.02 13.0 0.0 0.033 12.3 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EDO19165.1 - 0.027 14.2 0.2 0.67 9.7 0.0 2.9 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Med16 PF11635.3 EDO19165.1 - 0.048 11.6 0.0 1.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Mediator complex subunit 16 BAF1_ABF1 PF04684.8 EDO19168.1 - 0.0055 15.6 28.6 0.0087 14.9 19.9 1.3 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DUF4175 PF13779.1 EDO19168.1 - 8.8 3.8 33.6 15 3.0 23.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ABC_tran PF00005.22 EDO19169.1 - 1.3e-50 171.2 0.0 6.7e-25 87.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EDO19169.1 - 1.6e-22 80.7 1.9 2.8e-06 27.5 0.0 4.4 2 2 1 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 EDO19169.1 - 1.8e-21 75.7 1.4 1.8e-21 75.7 1.0 3.0 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 EDO19169.1 - 2.5e-10 39.9 1.6 0.55 9.4 0.0 4.8 3 1 1 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EDO19169.1 - 1.3e-08 35.0 0.0 0.0084 16.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EDO19169.1 - 2.8e-08 33.1 0.0 0.0032 16.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EDO19169.1 - 2.9e-08 33.0 0.0 2.8e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDO19169.1 - 3e-08 34.4 0.0 0.0049 17.6 0.0 3.3 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 EDO19169.1 - 9.9e-08 32.5 0.0 0.0023 18.4 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 EDO19169.1 - 1.6e-07 31.6 0.1 0.0051 17.1 0.0 3.2 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EDO19169.1 - 1.6e-06 28.0 0.0 0.011 15.7 0.1 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.7 EDO19169.1 - 3.1e-06 26.9 1.1 0.028 14.0 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA PF00004.24 EDO19169.1 - 3.8e-06 27.1 0.0 0.029 14.5 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EDO19169.1 - 1.1e-05 25.3 0.0 0.057 13.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 EDO19169.1 - 1.3e-05 25.2 0.0 0.13 12.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EDO19169.1 - 2.5e-05 24.2 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EDO19169.1 - 6.1e-05 23.4 14.7 0.017 15.4 0.0 4.1 4 1 0 4 4 3 2 AAA domain AAA_15 PF13175.1 EDO19169.1 - 6.9e-05 22.0 0.0 0.54 9.2 0.0 3.4 4 1 0 4 4 3 2 AAA ATPase domain AAA_10 PF12846.2 EDO19169.1 - 7.5e-05 22.3 0.0 0.28 10.5 0.0 3.1 3 0 0 3 3 3 2 AAA-like domain AAA_16 PF13191.1 EDO19169.1 - 9.1e-05 22.5 0.2 0.18 11.7 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EDO19169.1 - 9.9e-05 22.2 0.0 0.52 10.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain VirE PF05272.6 EDO19169.1 - 0.00021 20.8 0.1 0.28 10.6 0.0 2.9 3 0 0 3 3 3 1 Virulence-associated protein E MobB PF03205.9 EDO19169.1 - 0.00027 20.6 0.2 0.0075 15.9 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EDO19169.1 - 0.00055 19.7 0.1 0.5 10.1 0.0 3.5 2 1 1 3 3 3 1 Dynamin family Arch_ATPase PF01637.13 EDO19169.1 - 0.00075 19.2 0.1 1.9 8.1 0.0 3.1 3 0 0 3 3 3 2 Archaeal ATPase AAA_25 PF13481.1 EDO19169.1 - 0.00081 18.8 0.0 2.2 7.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain MCM PF00493.18 EDO19169.1 - 0.0016 17.3 1.1 1.1 7.9 0.0 3.0 3 0 0 3 3 3 1 MCM2/3/5 family T2SE PF00437.15 EDO19169.1 - 0.002 17.0 0.0 0.11 11.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_5 PF07728.9 EDO19169.1 - 0.0026 17.5 0.1 2.1 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ArgK PF03308.11 EDO19169.1 - 0.003 16.3 0.0 0.7 8.6 0.0 2.7 3 0 0 3 3 3 1 ArgK protein DUF815 PF05673.8 EDO19169.1 - 0.0069 15.3 1.4 2.2 7.1 0.1 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF815) Rad17 PF03215.10 EDO19169.1 - 0.0071 15.0 0.1 2.1 6.9 0.0 2.6 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 EDO19169.1 - 0.0071 15.2 0.0 2.9 6.6 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 EDO19169.1 - 0.015 15.0 0.1 0.56 9.8 0.0 2.6 2 0 0 2 2 2 0 NTPase DAP3 PF10236.4 EDO19169.1 - 0.017 14.0 0.6 5.2 5.9 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 PduV-EutP PF10662.4 EDO19169.1 - 0.018 14.4 0.1 6.1 6.3 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 EDO19169.1 - 0.02 14.8 1.0 1.3 9.0 0.0 3.4 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit FeoB_N PF02421.13 EDO19169.1 - 0.035 13.3 0.0 1 8.6 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF87 PF01935.12 EDO19169.1 - 0.036 13.8 1.4 12 5.5 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function DUF87 UPF0079 PF02367.12 EDO19169.1 - 0.056 13.0 0.0 5.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF695 PF05117.7 EDO19169.1 - 0.066 13.1 0.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF695) SRP54 PF00448.17 EDO19169.1 - 0.079 12.3 0.7 1.9 7.8 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF2813 PF11398.3 EDO19169.1 - 0.087 11.8 0.2 4.4 6.2 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF2813) AAA_30 PF13604.1 EDO19169.1 - 0.17 11.4 2.4 3.2 7.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.15 EDO19169.1 - 7.9 5.0 8.5 23 3.5 2.4 2.8 3 1 0 3 3 3 0 G-protein alpha subunit HAD_2 PF13419.1 EDO19170.1 - 3.3e-22 79.5 0.0 7.1e-22 78.4 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO19170.1 - 0.00049 20.5 0.0 0.13 12.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UAA PF08449.6 EDO19171.1 - 4.2e-12 45.6 17.5 5.3e-12 45.2 12.1 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EDO19171.1 - 3.1e-06 26.9 3.6 3.1e-06 26.9 2.5 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EDO19171.1 - 0.27 11.2 27.5 0.18 11.8 8.7 2.4 2 0 0 2 2 2 0 EamA-like transporter family Multi_Drug_Res PF00893.14 EDO19171.1 - 6.9 7.2 18.2 0.053 13.9 3.2 3.2 4 0 0 4 4 4 0 Small Multidrug Resistance protein SUI1 PF01253.17 EDO19172.1 - 1.1e-21 76.3 2.7 1.1e-21 76.3 1.9 1.7 2 0 0 2 2 2 1 Translation initiation factor SUI1 PilN PF05137.8 EDO19172.1 - 0.094 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Fimbrial assembly protein (PilN) TPR_16 PF13432.1 EDO19173.1 - 2e-05 25.1 0.8 1.8 9.3 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EDO19173.1 - 0.00043 19.8 11.4 0.02 14.5 0.1 5.2 6 1 1 7 7 7 3 TPR repeat TPR_2 PF07719.12 EDO19173.1 - 0.00062 19.4 3.7 9 6.4 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EDO19173.1 - 0.0017 18.8 0.2 0.19 12.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EDO19173.1 - 0.02 15.2 0.3 31 5.0 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4186 PF13811.1 EDO19173.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) DUF3963 PF13124.1 EDO19173.1 - 0.16 11.7 1.1 0.38 10.5 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) Thi4 PF01946.12 EDO19174.1 - 3.7e-99 330.4 0.5 4.5e-99 330.2 0.3 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EDO19174.1 - 7.5e-08 31.6 1.6 2.7e-07 29.8 0.3 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO19174.1 - 3.5e-06 26.9 0.1 9.3e-06 25.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EDO19174.1 - 1.8e-05 23.7 1.8 0.00065 18.6 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EDO19174.1 - 0.00011 22.0 0.2 0.00069 19.4 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EDO19174.1 - 0.00014 20.9 0.4 0.00021 20.3 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EDO19174.1 - 0.0018 18.4 0.1 0.0033 17.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EDO19174.1 - 0.0052 16.6 0.3 0.0052 16.6 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EDO19174.1 - 0.0056 15.1 0.5 0.015 13.7 0.4 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EDO19174.1 - 0.02 14.0 1.1 0.032 13.3 0.8 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EDO19174.1 - 0.035 12.9 0.1 0.08 11.7 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A PMT PF02366.13 EDO19175.1 - 8.8e-88 293.7 25.2 8.8e-88 293.7 17.5 2.3 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EDO19175.1 - 3.9e-23 81.9 1.6 7.4e-23 81.0 1.1 1.5 1 0 0 1 1 1 1 MIR domain WD40 PF00400.27 EDO19176.1 - 2.1e-64 211.2 18.6 3.5e-10 39.3 0.0 12.4 13 0 0 13 13 13 9 WD domain, G-beta repeat BBS2_Mid PF14783.1 EDO19176.1 - 1.4e-07 31.3 0.0 0.95 9.2 0.0 5.8 7 0 0 7 7 7 3 Ciliary BBSome complex subunit 2, middle region ILVD_EDD PF00920.16 EDO19177.1 - 1.8e-207 689.9 0.2 2.1e-207 689.7 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Rhodanese PF00581.15 EDO19178.1 - 4.6e-13 49.5 0.1 6.3e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF2924 PF11149.3 EDO19178.1 - 0.047 13.7 0.0 0.066 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) FTHFS PF01268.14 EDO19179.1 - 2.2e-257 854.5 0.2 3e-257 854.0 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EDO19179.1 - 1.1e-61 206.6 0.1 1.1e-61 206.6 0.1 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EDO19179.1 - 1.5e-38 131.4 0.8 3.7e-38 130.1 0.6 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF1859 PF08948.5 EDO19179.1 - 0.0044 16.7 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1859) AdoHcyase_NAD PF00670.16 EDO19179.1 - 0.039 13.7 0.2 3.1 7.6 0.1 2.7 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acyl_CoA_thio PF02551.10 EDO19180.1 - 2.6e-39 133.8 2.0 8.4e-30 103.0 0.3 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 EDO19180.1 - 4.8e-28 98.6 0.0 6.6e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF285 PF03382.9 EDO19180.1 - 0.014 14.9 0.1 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 AAA_17 PF13207.1 EDO19181.1 - 0.0012 19.6 0.3 0.023 15.5 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EDO19181.1 - 0.017 15.0 0.0 0.039 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EDO19181.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EDO19181.1 - 0.045 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 EDO19181.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mer2 PF09074.5 EDO19182.1 - 2.2e-70 236.4 9.0 2.2e-70 236.4 6.2 1.6 2 0 0 2 2 2 1 Mer2 HisK_N PF09385.5 EDO19182.1 - 0.013 15.1 2.1 0.37 10.3 0.2 3.0 1 1 2 3 3 3 0 Histidine kinase N terminal PMC2NT PF08066.7 EDO19182.1 - 0.017 15.4 3.4 0.064 13.5 1.2 2.5 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Baculo_PEP_C PF04513.7 EDO19182.1 - 0.074 12.8 6.8 0.42 10.4 0.5 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TA0956 PF11513.3 EDO19182.1 - 0.1 12.6 2.0 0.35 10.9 1.4 2.0 1 1 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 DUF2972 PF11186.3 EDO19182.1 - 0.25 11.1 5.7 0.035 13.9 0.9 1.9 2 2 0 2 2 2 0 Protein of unknown function (DUF2972) Fzo_mitofusin PF04799.8 EDO19182.1 - 0.52 9.6 8.1 0.085 12.2 0.5 2.6 1 1 3 4 4 4 0 fzo-like conserved region Mgr1 PF08602.5 EDO19182.1 - 0.77 8.7 6.7 0.31 10.0 0.6 2.1 1 1 1 2 2 2 0 Mgr1-like, i-AAA protease complex subunit DUF4208 PF13907.1 EDO19182.1 - 2 8.6 8.5 4 7.7 0.7 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4208) Aldolase_II PF00596.16 EDO19183.1 - 3.5e-41 140.8 0.0 4.1e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain 3-HAO PF06052.7 EDO19184.1 - 1.8e-63 212.4 0.0 2e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EDO19184.1 - 8.3e-05 22.0 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Nudix_N_2 PF14803.1 EDO19184.1 - 0.011 15.4 0.6 4.9 6.9 0.1 2.6 2 0 0 2 2 2 0 Nudix N-terminal DZR PF12773.2 EDO19184.1 - 0.014 15.1 0.1 0.83 9.5 0.0 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EDO19184.1 - 0.12 11.5 2.8 1.4 8.2 1.9 2.2 1 1 0 1 1 1 0 zinc-ribbon domain C1_1 PF00130.17 EDO19184.1 - 0.14 11.8 1.0 1.8 8.3 0.1 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_2 PF13240.1 EDO19184.1 - 0.8 9.2 3.1 1.6 8.3 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-RanBP PF00641.13 EDO19184.1 - 1 8.5 4.2 13 4.9 0.3 2.3 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Mvb12 PF09452.5 EDO19185.1 - 3.2e-24 84.8 0.0 3.7e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 UPF0203 PF05254.7 EDO19185.1 - 0.13 12.1 2.8 0.68 9.8 0.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) HAD PF12710.2 EDO19186.1 - 1.2e-11 45.1 1.1 2.5e-11 44.1 0.5 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EDO19186.1 - 1.4e-08 34.6 0.4 1.4e-07 31.3 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EDO19186.1 - 5.1e-06 27.0 1.0 0.00059 20.3 0.0 2.7 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EDO19186.1 - 0.00012 22.3 0.5 0.0037 17.5 0.2 2.8 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EDO19186.1 - 0.0013 17.9 0.9 0.003 16.7 0.6 1.6 1 1 0 1 1 1 1 Putative Phosphatase MMR_HSR1_C PF08438.5 EDO19187.1 - 2.5e-32 111.3 0.0 5.7e-32 110.2 0.0 1.6 2 0 0 2 2 2 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EDO19187.1 - 3.1e-18 65.7 0.0 7e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO19187.1 - 9.1e-06 25.0 0.1 3.8e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_10 PF12846.2 EDO19187.1 - 0.0074 15.7 0.0 0.082 12.3 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain GTP_EFTU PF00009.22 EDO19187.1 - 0.0087 15.5 0.1 4.3 6.7 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EDO19187.1 - 0.016 15.9 0.3 0.8 10.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EDO19187.1 - 0.034 13.9 0.4 0.15 11.9 0.1 2.2 3 0 0 3 3 3 0 Dynamin family ArgK PF03308.11 EDO19187.1 - 0.064 12.0 0.1 0.2 10.3 0.0 1.9 2 0 0 2 2 2 0 ArgK protein KTI12 PF08433.5 EDO19187.1 - 0.083 12.0 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 EDO19187.1 - 0.13 11.7 0.1 0.34 10.3 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EDO19187.1 - 0.16 11.4 0.5 9.5 5.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EDO19187.1 - 0.19 12.0 0.8 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain zf-ZPR1 PF03367.8 EDO19188.1 - 6e-119 392.8 2.8 3e-59 198.8 0.2 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Cytochrom_C_2 PF01322.15 EDO19188.1 - 0.014 15.9 2.0 5.2 7.6 0.1 4.0 4 0 0 4 4 4 0 Cytochrome C' zinc_ribbon_4 PF13717.1 EDO19188.1 - 0.07 12.8 4.2 1.8 8.2 0.1 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EDO19188.1 - 0.11 12.1 4.1 2.4 7.8 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EDO19188.1 - 0.32 10.7 2.2 9.9 5.9 0.0 3.4 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Elf1 PF05129.8 EDO19188.1 - 6.7 6.4 10.5 10 5.9 0.0 3.4 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like Ribosomal_S2 PF00318.15 EDO19189.1 - 9.8e-39 132.7 0.0 2.8e-20 72.4 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Gpi1 PF05024.10 EDO19190.1 - 2e-57 193.9 18.1 3.6e-57 193.1 12.5 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Ion_trans PF00520.26 EDO19191.1 - 1.2e-83 279.3 110.4 1e-31 109.7 3.4 6.4 7 0 0 7 7 7 4 Ion transport protein CRM1_C PF08767.6 EDO19192.1 - 5.4e-132 439.5 5.6 5.4e-132 439.5 3.9 3.2 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EDO19192.1 - 2.2e-38 131.4 5.6 2.2e-38 131.4 3.9 4.6 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EDO19192.1 - 3.7e-14 52.3 0.1 2.3e-13 49.8 0.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain Ribosomal_L3 PF00297.17 EDO19193.1 - 6.3e-44 150.3 0.8 1.8e-42 145.6 0.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L6 PF00347.18 EDO19194.1 - 1.7e-26 92.5 1.5 2.4e-12 47.1 1.2 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S4 PF00163.14 EDO19195.1 - 3.7e-24 84.9 0.7 1.1e-23 83.4 0.8 1.5 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EDO19195.1 - 5.9e-13 48.0 0.0 4.1e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.6 EDO19195.1 - 0.0065 14.9 0.0 0.0074 14.7 0.0 1.1 1 0 0 1 1 1 1 Herpesvirus Latent membrane protein 2 SKG6 PF08693.5 EDO19196.1 - 1.4e-11 43.4 1.9 2.8e-11 42.5 1.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EDO19196.1 - 0.0038 16.7 0.0 0.011 15.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.1 EDO19196.1 - 1.9 8.9 0.0 1.9 8.9 0.0 3.5 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain PH PF00169.24 EDO19197.1 - 0.0058 16.8 0.9 0.024 14.8 0.6 2.0 1 1 0 1 1 1 1 PH domain SET_assoc PF11767.3 EDO19197.1 - 0.42 9.9 3.9 0.34 10.2 1.3 1.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated WD40 PF00400.27 EDO19198.1 - 1.9e-06 27.5 0.0 0.041 13.7 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Pex24p PF06398.6 EDO19199.1 - 5.1e-79 265.6 1.0 7.1e-79 265.1 0.7 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PRT_C PF08372.5 EDO19199.1 - 0.0063 16.0 1.6 0.18 11.2 0.1 2.3 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal Polysacc_synt_3 PF13440.1 EDO19199.1 - 0.034 13.5 0.2 0.07 12.5 0.2 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Lectin_C PF00059.16 EDO19200.1 - 8.1e-05 23.2 6.2 0.007 16.9 1.7 3.0 3 0 0 3 3 3 2 Lectin C-type domain DIE2_ALG10 PF04922.7 EDO19201.1 - 4.4e-124 414.3 40.5 7.6e-124 413.5 28.1 1.4 1 0 0 1 1 1 1 DIE2/ALG10 family Spo12 PF05032.7 EDO19202.1 - 4e-19 67.9 1.2 9.4e-19 66.7 0.8 1.7 1 0 0 1 1 1 1 Spo12 family Band_7 PF01145.20 EDO19203.1 - 5.8e-23 81.7 1.1 5.8e-23 81.7 0.8 1.4 2 0 0 2 2 2 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 EDO19203.1 - 0.026 13.8 0.7 0.04 13.2 0.5 1.2 1 0 0 1 1 1 0 MraW methylase family E_Pc_C PF06752.7 EDO19203.1 - 0.065 12.7 0.1 0.23 10.9 0.1 1.9 2 1 0 2 2 2 0 Enhancer of Polycomb C-terminus Ank_2 PF12796.2 EDO19204.1 - 6.3e-42 141.8 0.5 1.3e-20 73.4 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EDO19204.1 - 6.8e-39 129.7 0.6 2.2e-09 36.6 0.0 5.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EDO19204.1 - 6.3e-35 118.9 1.5 2.4e-13 50.1 0.0 4.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDO19204.1 - 2.9e-34 116.3 0.8 1.3e-09 37.9 0.0 5.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EDO19204.1 - 3.4e-32 107.2 0.1 2.9e-06 26.9 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat BRCT PF00533.21 EDO19205.1 - 4.7e-17 61.8 11.8 2.8e-05 24.1 0.0 5.9 5 1 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EDO19205.1 - 3.4e-13 49.2 0.8 3.5e-07 29.9 0.0 3.9 4 0 0 4 4 4 2 twin BRCT domain FAD_binding_6 PF00970.19 EDO19206.1 - 3.3e-09 36.7 0.0 6.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 EDO19206.1 - 1e-08 35.5 0.1 1e-07 32.2 0.0 2.5 3 0 0 3 3 3 1 Globin NAD_binding_1 PF00175.16 EDO19206.1 - 1.8e-06 28.4 0.0 3.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 EDO19206.1 - 0.013 15.1 0.3 0.037 13.6 0.1 1.9 2 1 0 2 2 2 0 Protoglobin NAD_binding_6 PF08030.7 EDO19206.1 - 0.18 11.7 0.6 0.91 9.4 0.4 2.1 1 1 1 2 2 2 0 Ferric reductase NAD binding domain ApoO PF09769.4 EDO19207.1 - 3.5e-40 137.2 0.0 4.5e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein O HK97-gp10_like PF04883.7 EDO19209.1 - 0.028 15.3 0.1 0.074 14.0 0.1 1.7 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Kelch_3 PF13415.1 EDO19211.1 - 4.2e-34 115.9 2.4 1.2e-07 31.6 0.0 5.9 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EDO19211.1 - 6.9e-28 96.1 10.6 1.6e-05 24.7 0.0 6.6 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 EDO19211.1 - 4.4e-27 93.6 15.7 7e-06 25.7 0.2 6.7 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EDO19211.1 - 9.6e-26 88.8 13.6 2.7e-08 33.6 0.2 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EDO19211.1 - 1.2e-21 75.9 6.2 4.6e-07 29.2 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EDO19211.1 - 2.1e-13 49.4 8.7 0.14 11.9 0.0 6.9 6 1 0 6 6 6 4 Kelch motif CENP-Q PF13094.1 EDO19212.1 - 0.0022 18.0 4.4 0.01 15.8 0.8 2.5 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF3316 PF11777.3 EDO19212.1 - 0.023 14.4 1.7 0.04 13.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) Spore_III_AF PF09581.5 EDO19212.1 - 6.8 6.5 14.6 0.67 9.7 1.5 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) ApoLp-III PF07464.6 EDO19213.1 - 0.034 14.1 3.5 0.035 14.1 1.4 1.8 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PFK PF00365.15 EDO19214.1 - 9.9e-169 559.5 1.4 2.3e-123 410.6 0.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAP_epimerase PF01678.14 EDO19214.1 - 0.081 12.8 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Diaminopimelate epimerase OCC1 PF15506.1 EDO19214.1 - 0.11 12.4 0.0 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 OCC1 family ATP-grasp_2 PF08442.5 EDO19215.1 - 9.5e-68 227.5 0.4 1.4e-67 227.0 0.3 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EDO19215.1 - 7.8e-21 74.2 0.1 1.7e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 CoA-ligase CPDase PF07823.6 EDO19217.1 - 1.6e-58 197.4 0.0 2.1e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EDO19217.1 - 0.00018 21.2 0.0 0.0014 18.3 0.0 1.9 1 1 1 2 2 2 2 2'-5' RNA ligase superfamily Glucosamine_iso PF01182.15 EDO19218.1 - 7.7e-54 182.4 0.0 9.3e-54 182.1 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HSF_DNA-bind PF00447.12 EDO19219.1 - 7.8e-28 96.6 3.1 1.6e-27 95.6 2.2 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Dna2 PF08696.6 EDO19220.1 - 1.2e-67 227.3 1.4 2.8e-67 226.0 1.0 1.7 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EDO19220.1 - 6.4e-48 162.7 0.4 1.3e-47 161.7 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EDO19220.1 - 3.5e-42 144.6 4.6 6e-39 134.0 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EDO19220.1 - 9.6e-12 44.8 0.0 2.7e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EDO19220.1 - 2.6e-07 30.2 0.0 5.3e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EDO19220.1 - 1.2e-06 28.2 0.1 0.036 13.5 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF911 PF06023.7 EDO19220.1 - 0.0002 20.6 0.1 0.00042 19.6 0.1 1.4 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) Helicase_RecD PF05127.9 EDO19220.1 - 0.00037 20.1 0.0 0.00086 18.9 0.0 1.6 1 0 0 1 1 1 1 Helicase Cas_Cas4 PF01930.12 EDO19220.1 - 0.00061 19.7 0.1 0.017 15.0 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF83 SRP54 PF00448.17 EDO19220.1 - 0.0033 16.8 0.0 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EDO19220.1 - 0.0084 15.9 0.0 0.56 10.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EDO19220.1 - 0.009 15.7 0.1 0.027 14.1 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 EDO19220.1 - 0.012 15.4 0.2 0.012 15.4 0.1 3.4 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EDO19220.1 - 0.014 15.1 0.0 0.055 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO19220.1 - 0.023 14.6 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EDO19220.1 - 0.052 13.8 7.8 0.072 13.3 0.0 3.9 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EDO19220.1 - 0.086 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PROCN PF08083.6 EDO19221.1 - 1.1e-217 722.4 15.5 1.7e-217 721.7 10.8 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EDO19221.1 - 1.8e-122 406.9 1.8 3.7e-122 405.9 1.3 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EDO19221.1 - 3.9e-88 292.8 0.8 9.5e-88 291.5 0.6 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EDO19221.1 - 7.5e-78 259.4 3.7 1.7e-77 258.2 2.5 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EDO19221.1 - 3.5e-65 217.6 0.0 7.7e-65 216.5 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EDO19221.1 - 7.3e-45 151.7 0.1 2e-44 150.2 0.1 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 EDO19221.1 - 1.2e-43 146.8 0.3 3.3e-43 145.4 0.2 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 EDO19221.1 - 0.00052 19.7 0.0 0.022 14.5 0.0 2.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease APC8 PF04049.8 EDO19222.1 - 7.8e-35 119.6 0.0 1.6e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 EDO19222.1 - 4.6e-21 74.2 27.5 1.4e-09 37.4 0.1 6.6 3 1 2 6 6 6 4 TPR repeat TPR_1 PF00515.23 EDO19222.1 - 6.7e-21 72.9 27.2 4.1e-06 26.1 0.0 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 EDO19222.1 - 2.1e-19 67.8 25.3 0.0029 17.4 0.0 9.2 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EDO19222.1 - 6.5e-19 66.2 31.4 0.00064 19.3 0.0 9.1 7 1 2 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 EDO19222.1 - 1.5e-15 56.8 17.0 3.1e-05 23.8 0.7 5.8 2 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDO19222.1 - 2.3e-14 52.5 3.8 0.00076 19.9 0.0 6.4 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDO19222.1 - 3.8e-12 46.5 5.3 1.2e-05 25.8 0.0 5.4 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDO19222.1 - 7.8e-11 41.2 11.8 0.0011 18.9 0.0 6.1 6 0 0 6 6 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 EDO19222.1 - 4.5e-09 35.4 7.7 0.017 14.9 0.1 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat ChAPs PF09295.5 EDO19222.1 - 1.2e-06 27.5 0.3 7.4e-05 21.6 0.0 2.2 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.4 EDO19222.1 - 0.00032 20.1 8.0 0.00044 19.6 1.1 3.2 4 0 0 4 4 4 1 26S proteasome subunit RPN7 TPR_15 PF13429.1 EDO19222.1 - 0.00081 18.5 4.5 0.45 9.5 0.5 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EDO19222.1 - 0.0014 18.9 11.8 0.78 10.1 0.0 5.5 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EDO19222.1 - 0.0021 17.8 0.8 2.6 7.9 0.1 3.0 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EDO19222.1 - 0.005 16.7 7.4 1.1 9.2 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat BTAD PF03704.12 EDO19222.1 - 0.018 15.3 0.1 0.018 15.3 0.1 2.2 2 1 0 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.13 EDO19222.1 - 0.03 14.1 1.5 0.39 10.6 0.0 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DUF1221 PF06760.6 EDO19222.1 - 0.037 13.2 1.7 3.1 7.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1221) YscJ_FliF_C PF08345.6 EDO19222.1 - 0.11 12.5 1.0 0.19 11.6 0.7 1.3 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal TPR_6 PF13174.1 EDO19222.1 - 1.5 9.4 21.3 35 5.1 0.0 8.3 10 1 0 10 10 8 0 Tetratricopeptide repeat THP2 PF09432.5 EDO19223.1 - 7.4e-57 190.8 5.8 7.4e-57 190.8 4.0 1.9 2 0 0 2 2 2 1 Tho complex subunit THP2 Alpha_kinase PF02816.13 EDO19223.1 - 0.15 11.6 3.9 0.13 11.8 0.2 2.3 3 0 0 3 3 3 0 Alpha-kinase family GTP1_OBG PF01018.17 EDO19224.1 - 3e-34 117.9 3.0 2.5e-24 85.6 1.3 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EDO19224.1 - 3e-21 75.5 0.0 4.9e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO19224.1 - 1.6e-10 40.4 0.0 2.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 EDO19224.1 - 3.2e-09 36.2 0.0 7.1e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EDO19224.1 - 5e-06 26.0 0.1 0.0004 19.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EDO19224.1 - 0.00013 22.4 0.0 0.00028 21.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EDO19224.1 - 0.00034 20.0 0.0 0.0011 18.3 0.0 1.9 1 1 0 1 1 1 1 Ras family ArgK PF03308.11 EDO19224.1 - 0.019 13.7 0.1 0.78 8.4 0.0 2.1 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 EDO19224.1 - 0.029 14.1 0.0 7.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin family SRPRB PF09439.5 EDO19224.1 - 0.038 13.1 0.5 7.2 5.7 0.1 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AIG1 PF04548.11 EDO19224.1 - 0.044 12.8 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family DUF2702 PF10863.3 EDO19225.1 - 1.1e-57 193.7 8.2 1.1e-57 193.7 5.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2702) Opi1 PF08618.5 EDO19225.1 - 0.011 14.7 2.5 0.013 14.4 1.7 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 DUF4661 PF15576.1 EDO19225.1 - 0.063 12.9 5.1 0.12 11.9 2.3 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4661) ThiF PF00899.16 EDO19226.1 - 3e-31 108.0 0.0 6.6e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EDO19226.1 - 0.0017 18.4 0.0 0.0057 16.7 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Toprim PF01751.17 EDO19226.1 - 0.022 14.7 0.1 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 Toprim domain 2-Hacid_dh_C PF02826.14 EDO19226.1 - 0.13 11.3 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EDO19226.1 - 0.16 11.3 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Enolase_C PF00113.17 EDO19227.1 - 4.8e-152 505.0 0.0 7e-152 504.5 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EDO19227.1 - 5.4e-59 197.8 0.6 8.5e-59 197.2 0.4 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EDO19227.1 - 0.0022 17.9 0.1 0.0072 16.2 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EDO19227.1 - 0.019 13.9 0.3 0.056 12.3 0.0 1.8 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Peptidase_M16 PF00675.15 EDO19228.1 - 6.6e-30 103.8 0.0 1.3e-29 102.9 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDO19228.1 - 1.3e-09 37.9 0.1 0.0029 17.2 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Hairy_orange PF07527.8 EDO19228.1 - 0.082 12.6 0.0 20 5.0 0.0 3.3 3 0 0 3 3 3 0 Hairy Orange DUF2378 PF09536.5 EDO19228.1 - 0.41 10.1 0.0 0.71 9.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2378) Acetyltransf_7 PF13508.1 EDO19229.1 - 5.4e-06 26.4 0.0 2.3e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EDO19229.1 - 0.00065 19.5 0.0 0.0061 16.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EDO19229.1 - 0.006 16.5 0.0 0.023 14.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EDO19229.1 - 0.0077 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein LMSTEN PF07988.7 EDO19229.1 - 0.015 14.5 0.4 0.17 11.2 0.0 2.6 3 0 0 3 3 3 0 LMSTEN motif SURF1 PF02104.10 EDO19230.1 - 2.8e-66 223.3 0.0 3.9e-66 222.9 0.0 1.2 1 0 0 1 1 1 1 SURF1 family DASH_Dam1 PF08653.5 EDO19231.1 - 1.1e-26 92.2 0.1 2.2e-26 91.3 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Dam1 Phage_pRha PF09669.5 EDO19231.1 - 0.061 13.6 1.6 0.38 11.1 0.1 2.5 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Ctr PF04145.10 EDO19232.1 - 8.6e-28 97.1 2.6 8.6e-28 97.1 1.8 2.1 3 0 0 3 3 3 1 Ctr copper transporter family SH2_2 PF14633.1 EDO19233.1 - 6.6e-102 339.2 2.9 3.4e-101 336.9 1.7 2.4 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.1 EDO19233.1 - 1.1e-62 210.0 0.0 4.9e-62 207.9 0.0 2.2 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 EDO19233.1 - 6.5e-49 164.8 4.1 6.5e-49 164.8 2.8 3.7 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 EDO19233.1 - 1.4e-41 140.8 0.1 4e-41 139.3 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 EDO19233.1 - 5.7e-33 113.4 6.5 6.1e-33 113.3 2.4 2.8 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EDO19233.1 - 3e-22 78.5 21.9 3e-22 78.5 15.2 6.1 4 2 3 7 7 7 1 Acidic N-terminal SPT6 SH2 PF00017.19 EDO19233.1 - 1.8e-12 46.8 0.2 8.5e-12 44.7 0.0 2.3 2 0 0 2 2 2 1 SH2 domain LETM1 PF07766.8 EDO19234.1 - 1.6e-92 309.3 1.8 2.5e-92 308.7 1.2 1.3 1 0 0 1 1 1 1 LETM1-like protein ACOX PF01756.14 EDO19234.1 - 0.014 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA oxidase Mito_carr PF00153.22 EDO19235.1 - 5.9e-57 189.3 3.6 6.5e-20 70.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BTB PF00651.26 EDO19235.1 - 0.027 14.4 0.1 0.42 10.6 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain Ribosom_S12_S23 PF00164.20 EDO19236.1 - 7e-41 138.4 0.6 8.2e-41 138.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Nup54 PF13874.1 EDO19237.1 - 6.5e-41 139.2 4.6 6.5e-41 139.2 3.2 2.3 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EDO19237.1 - 1.6e-21 76.6 149.2 1.2e-10 41.5 37.4 4.9 1 1 3 4 4 4 4 Nucleoporin FG repeat region DUF807 PF05660.6 EDO19237.1 - 0.027 14.1 0.2 0.053 13.1 0.1 1.5 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) COG2 PF06148.6 EDO19238.1 - 5.1e-07 29.6 8.8 5.1e-07 29.6 6.1 2.1 1 1 1 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Syntaxin_2 PF14523.1 EDO19238.1 - 0.0071 16.3 5.8 0.046 13.7 0.3 2.9 2 1 1 3 3 3 1 Syntaxin-like protein F_actin_bind PF08919.5 EDO19238.1 - 0.0093 15.6 0.5 0.0093 15.6 0.3 2.4 1 1 2 3 3 3 1 F-actin binding Rif1_N PF12231.3 EDO19238.1 - 0.016 14.1 2.2 0.18 10.7 0.2 2.2 1 1 1 2 2 2 0 Rap1-interacting factor 1 N terminal NusB PF01029.13 EDO19238.1 - 0.023 14.6 0.7 0.049 13.6 0.5 1.6 1 1 0 1 1 1 0 NusB family DUF883 PF05957.8 EDO19238.1 - 0.025 14.9 2.0 16 5.9 0.0 3.4 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Mnd1 PF03962.10 EDO19238.1 - 0.026 14.1 0.7 0.35 10.5 0.5 2.0 1 1 1 2 2 2 0 Mnd1 family DHDPS PF00701.17 EDO19238.1 - 0.041 12.4 0.1 0.079 11.5 0.0 1.5 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family LOH1CR12 PF10158.4 EDO19238.1 - 0.08 12.7 2.7 1.1 9.1 1.4 2.6 1 1 1 2 2 2 0 Tumour suppressor protein DUF445 PF04286.7 EDO19238.1 - 0.12 11.9 2.2 0.16 11.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF2935 PF11155.3 EDO19238.1 - 0.12 12.4 2.8 2 8.5 1.0 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF2935) DUF2893 PF11459.3 EDO19238.1 - 0.14 11.9 1.3 2.6 7.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknwon function (DUF2893) Spectrin PF00435.16 EDO19238.1 - 0.14 12.4 3.0 1.5 9.1 1.1 2.7 1 1 2 3 3 3 0 Spectrin repeat DUF4208 PF13907.1 EDO19238.1 - 0.33 11.1 2.5 0.51 10.5 0.9 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4208) Mod_r PF07200.8 EDO19238.1 - 0.39 10.6 6.3 1.3 8.9 1.3 2.7 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Nse4-Nse3_bdg PF15412.1 EDO19238.1 - 0.42 10.5 5.1 12 5.8 0.1 3.5 4 2 0 4 4 3 0 Binding domain of Nse4/EID3 to Nse3-MAGE DivIVA PF05103.8 EDO19238.1 - 1 9.3 8.1 11 6.0 4.9 2.9 1 1 1 2 2 2 0 DivIVA protein DUF3639 PF12341.3 EDO19239.1 - 1.8e-11 43.7 0.1 4.8e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) WD40 PF00400.27 EDO19240.1 - 2.7e-23 80.9 1.9 1.8e-07 30.7 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Ammonium_transp PF00909.16 EDO19241.1 - 1e-119 399.6 23.1 1.1e-119 399.4 16.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF912 PF06024.7 EDO19242.1 - 0.023 14.7 0.4 0.054 13.5 0.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EDO19242.1 - 0.76 9.3 3.2 0.97 9.0 2.2 1.1 1 0 0 1 1 1 0 Rifin/stevor family Kinesin PF00225.18 EDO19243.1 - 5.2e-90 301.5 3.6 5.2e-90 301.5 2.5 2.5 2 1 1 3 3 3 1 Kinesin motor domain DERM PF14704.1 EDO19243.1 - 0.014 15.4 1.3 0.037 13.9 0.9 1.7 1 0 0 1 1 1 0 Dermatopontin PWWP PF00855.12 EDO19244.1 - 2.3e-06 27.6 0.2 2.3e-06 27.6 0.1 1.0 1 0 0 1 1 1 1 PWWP domain PWWP PF00855.12 EDO19245.1 - 1.5e-05 25.0 1.5 2.7e-05 24.2 0.0 2.2 3 0 0 3 3 3 1 PWWP domain ThiF PF00899.16 EDO19246.1 - 7.4e-18 64.6 0.1 1.8e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 ThiF family HHH_6 PF14579.1 EDO19246.1 - 0.12 12.4 0.1 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sec23_trunk PF04811.10 EDO19247.1 - 1.2e-71 240.9 0.0 1.6e-71 240.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EDO19247.1 - 1.4e-34 117.5 0.1 3.2e-34 116.4 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EDO19247.1 - 3.9e-30 104.2 0.2 9.4e-30 102.9 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EDO19247.1 - 8.4e-14 50.8 10.1 1.5e-13 50.0 7.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EDO19247.1 - 3e-11 42.8 0.0 6.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-MIZ PF02891.15 EDO19247.1 - 0.26 10.8 3.1 0.53 9.8 2.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PIG-U PF06728.8 EDO19248.1 - 8.4e-102 340.8 49.6 1e-101 340.5 34.4 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U zf-C2H2 PF00096.21 EDO19249.1 - 2e-26 90.6 60.3 0.0019 18.4 2.6 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO19249.1 - 5.5e-23 79.5 57.2 0.002 18.2 3.3 9.2 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO19249.1 - 3.3e-19 68.1 52.8 8.2e-05 22.7 0.7 9.6 9 0 0 9 9 9 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDO19249.1 - 1.2e-09 37.9 35.1 0.0017 18.4 0.0 7.8 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EDO19249.1 - 3.7e-07 30.1 28.8 0.0052 16.9 0.1 8.2 8 0 0 8 8 8 2 Zinc-finger of C2H2 type CpXC PF14353.1 EDO19249.1 - 0.0096 15.8 0.2 0.0096 15.8 0.1 4.2 3 2 0 4 4 4 1 CpXC protein zf-C2H2_2 PF12756.2 EDO19249.1 - 1.2 9.3 35.3 0.89 9.6 0.3 5.5 2 1 3 5 5 5 0 C2H2 type zinc-finger (2 copies) RNA_pol_Rpb6 PF01192.17 EDO19250.1 - 3.5e-23 81.0 0.2 5.2e-23 80.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 EF-hand_1 PF00036.27 EDO19251.1 - 9.4e-10 37.0 2.3 2.6e-06 26.3 0.3 3.7 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 EDO19251.1 - 1.2e-09 38.1 1.3 8e-09 35.5 0.8 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EDO19251.1 - 1.7e-09 36.7 1.9 1.7e-06 27.4 0.5 3.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EDO19251.1 - 3.4e-08 32.4 1.4 5.5e-06 25.4 0.5 3.3 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.1 EDO19251.1 - 0.00017 21.1 4.0 0.0042 16.6 0.1 3.4 2 2 1 4 4 4 2 EF-hand domain pair TPR_11 PF13414.1 EDO19252.1 - 1.3e-29 101.6 7.8 3.1e-08 33.1 0.0 9.3 6 3 5 11 11 11 8 TPR repeat TPR_19 PF14559.1 EDO19252.1 - 1.7e-23 82.7 0.0 2.2e-06 27.9 0.0 8.9 6 3 1 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 EDO19252.1 - 7.1e-23 78.6 4.5 0.00012 21.7 0.0 12.4 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_16 PF13432.1 EDO19252.1 - 1.1e-21 76.9 0.0 0.00063 20.3 0.0 7.4 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.23 EDO19252.1 - 2.1e-20 71.4 1.8 0.0001 21.7 0.0 11.4 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDO19252.1 - 1.1e-18 65.7 3.3 0.02 15.0 0.0 9.3 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDO19252.1 - 1.3e-17 62.6 0.0 0.011 16.2 0.0 10.5 8 3 5 13 13 10 4 Tetratricopeptide repeat Apc3 PF12895.2 EDO19252.1 - 9.6e-14 51.2 14.3 4.5e-06 26.7 0.0 7.5 7 2 1 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EDO19252.1 - 4.1e-13 48.8 0.1 0.15 12.5 0.0 9.2 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO19252.1 - 1.1e-11 43.5 21.1 0.0019 17.8 0.0 11.1 14 1 0 14 14 12 3 Tetratricopeptide repeat TPR_12 PF13424.1 EDO19252.1 - 1.2e-11 44.3 8.5 0.023 14.6 0.0 8.1 6 2 3 9 9 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EDO19252.1 - 4.7e-11 41.6 1.3 0.23 11.3 0.0 8.6 9 0 0 9 9 9 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EDO19252.1 - 0.0005 20.3 0.1 0.75 10.0 0.1 3.5 3 0 0 3 3 3 1 Alkyl sulfatase dimerisation NARP1 PF12569.3 EDO19252.1 - 0.0026 16.6 3.4 0.12 11.1 0.1 3.6 3 1 1 4 4 4 1 NMDA receptor-regulated protein 1 DUF627 PF04781.7 EDO19252.1 - 0.011 15.3 1.3 14 5.3 0.1 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF627) Rapamycin_bind PF08771.6 EDO19252.1 - 0.075 13.1 0.2 0.075 13.1 0.1 3.0 5 0 0 5 5 1 0 Rapamycin binding domain TPR_4 PF07721.9 EDO19252.1 - 0.19 12.2 0.0 71 4.2 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EDO19253.1 - 0.00031 20.4 0.1 0.0032 17.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EDO19253.1 - 0.00059 19.4 0.3 0.036 13.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO19253.1 - 0.0024 17.7 0.2 0.15 12.0 0.0 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EDO19253.1 - 0.0043 16.6 0.1 0.25 11.0 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EDO19253.1 - 0.021 14.4 0.1 0.17 11.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_Rpc82 PF05645.8 EDO19254.1 - 2.1e-71 240.5 1.0 2.6e-71 240.1 0.3 1.5 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EDO19254.1 - 2.6e-23 81.6 2.3 9.9e-18 63.7 0.1 3.6 3 0 0 3 3 3 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EDO19254.1 - 3e-06 26.6 2.5 0.0061 16.0 0.1 3.0 2 1 0 2 2 2 2 TFIIE alpha subunit Rio2_N PF09202.6 EDO19254.1 - 0.47 10.5 3.7 2.7 8.1 0.1 3.1 3 0 0 3 3 3 0 Rio2, N-terminal Peptidase_M16 PF00675.15 EDO19255.1 - 4.8e-23 81.5 0.0 9.9e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EDO19255.1 - 2.7e-11 43.4 0.4 1.4e-10 41.1 0.1 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain zf-H2C2_2 PF13465.1 EDO19256.1 - 1.2e-06 28.4 6.2 1.2e-06 28.4 4.3 4.4 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO19256.1 - 2.5e-06 27.4 19.7 0.0011 19.1 0.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EDO19256.1 - 0.0015 18.7 17.0 0.0025 18.0 1.1 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-met PF12874.2 EDO19256.1 - 0.0054 16.9 0.4 0.0054 16.9 0.3 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type FYRN PF05964.9 EDO19256.1 - 0.064 12.7 0.5 0.13 11.7 0.4 1.6 1 0 0 1 1 1 0 F/Y-rich N-terminus Flocculin PF00624.13 EDO19257.1 - 6.4e-242 781.3 894.2 4.8e-14 51.8 20.0 25.9 26 0 0 26 26 26 25 Flocculin repeat PA14 PF07691.7 EDO19257.1 - 1.4e-14 53.9 0.0 1.4e-14 53.9 0.0 8.9 9 6 7 16 16 16 1 PA14 domain PA14_2 PF10528.4 EDO19257.1 - 1.5e-13 50.7 0.5 4.4e-11 42.7 0.3 5.9 1 0 0 1 1 1 1 GLEYA domain ICL PF00463.16 EDO19259.1 - 1.2e-265 881.7 0.5 1.4e-265 881.5 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EDO19259.1 - 2.6e-10 39.9 0.0 4.3e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Terpene_synth_C PF03936.11 EDO19259.1 - 0.042 13.0 0.4 0.089 12.0 0.3 1.5 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain ECH_C PF13766.1 EDO19259.1 - 0.11 12.6 0.0 14 5.8 0.0 2.8 1 1 1 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Atg31 PF09795.4 EDO19260.1 - 5.2e-63 211.5 5.2 5.9e-63 211.3 3.6 1.0 1 0 0 1 1 1 1 Autophagy-related protein 31 DEAD PF00270.24 EDO19261.1 - 2e-41 141.3 2.3 5.6e-41 139.8 1.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO19261.1 - 1.2e-26 92.4 0.3 6.4e-26 90.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EDO19261.1 - 9.9e-05 22.0 0.2 0.00027 20.6 0.0 1.7 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EDO19261.1 - 0.00068 19.7 0.4 0.0025 17.9 0.3 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDO19261.1 - 0.0024 17.4 0.1 0.0049 16.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 EDO19261.1 - 0.0097 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 Helicase ResIII PF04851.10 EDO19261.1 - 0.01 15.6 0.2 0.025 14.4 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EDO19261.1 - 0.018 14.8 0.0 0.074 12.8 0.0 2.0 1 1 0 1 1 1 0 Flavivirus DEAD domain CMS1 PF14617.1 EDO19261.1 - 0.023 13.7 0.1 0.092 11.7 0.0 2.0 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit PhoH PF02562.11 EDO19261.1 - 0.035 13.3 4.9 0.07 12.3 2.3 2.3 2 1 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.16 EDO19261.1 - 0.038 13.2 0.1 0.046 13.0 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Helicase_C_2 PF13307.1 EDO19261.1 - 0.083 12.8 0.3 0.68 9.8 0.0 2.5 2 2 2 4 4 4 0 Helicase C-terminal domain PRK PF00485.13 EDO19262.1 - 4.6e-10 39.3 0.2 4.7e-09 36.0 0.0 1.9 1 1 1 2 2 2 1 Phosphoribulokinase / Uridine kinase family Spermine_synth PF01564.12 EDO19262.1 - 0.012 14.6 0.1 0.33 9.8 0.0 2.1 2 0 0 2 2 2 0 Spermine/spermidine synthase CbiG_N PF11760.3 EDO19262.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal TFIIE_beta PF02186.10 EDO19262.1 - 0.34 10.9 5.3 17 5.4 0.1 3.8 3 1 1 4 4 4 0 TFIIE beta subunit core domain GCV_T PF01571.16 EDO19263.1 - 4.2e-63 212.5 0.0 5.4e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EDO19263.1 - 3.1e-14 52.7 0.0 5.5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TrmE_N PF10396.4 EDO19263.1 - 0.013 15.4 0.0 2.6 8.0 0.0 3.0 2 1 1 3 3 3 0 GTP-binding protein TrmE N-terminus Diphtheria_R PF01324.14 EDO19263.1 - 0.092 12.2 0.1 13 5.3 0.0 2.8 3 0 0 3 3 3 0 Diphtheria toxin, R domain Acyltransferase PF01553.16 EDO19264.1 - 8.5e-27 93.1 0.0 1.6e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase AMP-binding PF00501.23 EDO19265.1 - 4.8e-61 206.4 0.0 6.4e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EDO19265.1 - 0.004 18.0 0.0 0.0076 17.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP-synt PF00231.14 EDO19266.1 - 1.6e-65 221.3 9.5 1.9e-65 221.1 6.6 1.0 1 0 0 1 1 1 1 ATP synthase Amdo_NSP PF12475.3 EDO19267.1 - 0.085 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Amdovirus non-structural protein CRCB PF02537.10 EDO19268.1 - 2.7e-29 101.4 21.6 7.1e-19 67.8 4.1 2.8 3 0 0 3 3 3 2 CrcB-like protein Bac_rhodopsin PF01036.13 EDO19268.1 - 0.0017 17.7 1.0 0.0029 16.9 0.6 1.6 1 1 0 1 1 1 1 Bacteriorhodopsin-like protein Rcd1 PF04078.8 EDO19268.1 - 0.062 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like NatB_MDM20 PF09797.4 EDO19270.1 - 3.9e-66 223.2 12.0 8.3e-66 222.1 8.4 1.6 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Hormone_2 PF00123.15 EDO19270.1 - 6 6.7 7.5 5.3 6.9 0.0 3.5 4 0 0 4 4 4 0 Peptide hormone DUF2611 PF11022.3 EDO19271.1 - 4.8e-28 97.0 0.1 5.2e-28 96.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Peptidase_S10 PF00450.17 EDO19272.1 - 9.1e-123 410.4 0.1 1.1e-122 410.2 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EDO19272.1 - 0.00052 19.9 0.0 0.0013 18.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family RasGAP PF00616.14 EDO19273.1 - 2.9e-34 118.4 3.4 2.9e-34 118.4 2.4 2.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RP-C_C PF11800.3 EDO19273.1 - 0.46 10.1 0.6 1.2 8.8 0.4 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF3321 PF11968.3 EDO19274.1 - 1.9e-84 282.7 0.2 2.6e-84 282.2 0.2 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Med18 PF09637.5 EDO19274.1 - 0.02 14.4 0.0 0.024 14.1 0.0 1.4 1 1 0 1 1 1 0 Med18 protein Methyltransf_23 PF13489.1 EDO19274.1 - 0.037 13.7 0.0 0.09 12.4 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain EF-hand_7 PF13499.1 EDO19274.1 - 0.28 11.3 3.8 2.6 8.2 0.2 3.5 3 1 0 3 3 3 0 EF-hand domain pair DUF1514 PF07438.6 EDO19274.1 - 1.2 9.1 3.7 3.2 7.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) DEAD PF00270.24 EDO19275.1 - 1.4e-38 132.0 0.1 6.2e-38 129.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO19275.1 - 1.1e-23 82.8 0.1 3.1e-23 81.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain eRF1_2 PF03464.10 EDO19276.1 - 1.1e-44 152.0 0.2 1.9e-44 151.1 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EDO19276.1 - 2.8e-37 127.4 0.4 5.9e-37 126.3 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EDO19276.1 - 1.5e-29 102.1 0.1 2.8e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 ADH_zinc_N PF00107.21 EDO19277.1 - 8.4e-28 96.5 1.0 1.4e-27 95.8 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO19277.1 - 8.5e-28 96.2 0.3 2.5e-27 94.7 0.2 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EDO19277.1 - 2.2e-05 25.3 0.1 5.5e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Ribosomal_S9 PF00380.14 EDO19278.1 - 8e-38 129.4 0.0 1.3e-37 128.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 CENP-S PF15630.1 EDO19279.1 - 2.1e-25 88.6 0.0 2.7e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EDO19279.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EDO19279.1 - 0.07 13.2 0.0 0.092 12.8 0.0 1.1 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF3337 PF11816.3 EDO19280.1 - 2.7e-73 247.2 6.1 2.7e-73 247.2 4.2 2.8 2 1 0 3 3 3 1 Domain of unknown function (DUF3337) WD40 PF00400.27 EDO19280.1 - 8.8e-13 47.6 13.0 0.00021 21.0 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat RNA_pol_Rpb5_N PF03871.9 EDO19281.1 - 2.3e-34 117.6 1.2 4e-34 116.9 0.8 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain RNA_pol_Rpb5_C PF01191.14 EDO19281.1 - 3.3e-33 113.1 1.5 3.8e-33 112.8 0.3 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain Sof1 PF04158.9 EDO19281.1 - 0.044 13.8 0.1 0.084 12.9 0.1 1.4 1 0 0 1 1 1 0 Sof1-like domain Mrr_cat PF04471.7 EDO19281.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease DUF3508 PF12018.3 EDO19281.1 - 0.076 11.9 0.1 0.12 11.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3508) SH3_2 PF07653.12 EDO19281.1 - 0.082 12.4 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain DUF4473 PF14747.1 EDO19282.1 - 0.0028 17.8 0.4 0.0076 16.4 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4473) Thioredoxin PF00085.15 EDO19283.1 - 3.1e-15 55.7 0.1 1.9e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EDO19283.1 - 0.00083 19.4 0.4 0.0031 17.6 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EDO19283.1 - 0.0024 18.0 0.7 0.0046 17.1 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Aldose_epim PF01263.15 EDO19284.1 - 1.5e-75 254.1 0.4 1.9e-75 253.7 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 EDO19284.1 - 1.5e-53 181.7 0.0 2.3e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EDO19284.1 - 5e-22 77.6 0.1 1.4e-21 76.1 0.1 1.8 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EDO19284.1 - 2.4e-18 66.0 0.0 1.6e-16 60.0 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EDO19284.1 - 6.7e-16 57.8 0.0 7.2e-15 54.4 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EDO19284.1 - 4.4e-12 45.4 0.0 7.8e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EDO19284.1 - 8.8e-11 42.0 0.0 1.4e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EDO19284.1 - 4.1e-09 36.3 0.0 7.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EDO19284.1 - 9.6e-09 34.5 0.0 2e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EDO19284.1 - 5.2e-06 26.5 0.0 8.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EDO19284.1 - 0.0055 15.9 0.1 0.017 14.3 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 EDO19284.1 - 0.085 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase GalKase_gal_bdg PF10509.4 EDO19285.1 - 6.6e-21 73.3 0.0 1.2e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EDO19285.1 - 3.8e-09 36.6 0.1 8.9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EDO19285.1 - 1.9e-08 34.2 0.3 5.5e-08 32.7 0.2 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain Sigma70_r4 PF04545.11 EDO19285.1 - 0.033 13.4 0.1 0.089 12.1 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_17 PF12728.2 EDO19285.1 - 0.049 13.8 0.0 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain ABC2_membrane PF01061.19 EDO19286.1 - 1e-69 233.8 51.1 8.7e-42 142.6 9.5 2.3 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EDO19286.1 - 1.5e-36 124.1 6.5 1.1e-32 111.7 0.0 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EDO19286.1 - 6.3e-36 123.7 0.0 2.8e-17 63.2 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.2 EDO19286.1 - 9.2e-14 51.2 33.8 9.1e-12 44.6 7.9 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EDO19286.1 - 1.7e-11 44.0 0.0 6.7e-11 42.1 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EDO19286.1 - 8.9e-06 24.9 0.0 0.001 18.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EDO19286.1 - 2e-05 24.0 0.0 0.0021 17.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EDO19286.1 - 0.0004 20.4 0.2 0.0057 16.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EDO19286.1 - 0.00044 19.7 0.2 0.0012 18.2 0.1 1.8 2 0 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EDO19286.1 - 0.00063 19.7 0.0 0.76 9.6 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 EDO19286.1 - 0.0024 18.0 0.4 0.019 15.1 0.1 2.8 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EDO19286.1 - 0.0029 17.0 0.1 0.062 12.8 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 EDO19286.1 - 0.0057 15.9 0.0 0.79 8.9 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain Miro PF08477.8 EDO19286.1 - 0.0089 16.5 0.0 0.61 10.5 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EDO19286.1 - 0.024 14.9 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EDO19286.1 - 0.027 14.1 0.6 0.45 10.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 EDO19286.1 - 0.032 14.0 0.9 0.17 11.7 0.0 2.4 2 0 0 2 2 2 0 Dynamin family MMR_HSR1 PF01926.18 EDO19286.1 - 0.036 14.0 0.1 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EDO19286.1 - 0.038 13.9 0.0 0.14 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EDO19286.1 - 0.053 13.2 0.6 10 5.9 0.0 3.4 3 0 0 3 3 3 0 Part of AAA domain AAA_17 PF13207.1 EDO19286.1 - 0.058 14.2 0.0 0.29 11.9 0.0 2.2 2 0 0 2 2 1 0 AAA domain Septin PF00735.13 EDO19286.1 - 0.071 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Septin ABC_ATPase PF09818.4 EDO19286.1 - 0.091 11.3 0.1 0.17 10.3 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.13 EDO19286.1 - 0.095 12.1 0.1 2.7 7.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.7 EDO19286.1 - 0.17 11.5 0.5 0.39 10.3 0.1 1.8 2 0 0 2 2 2 0 NACHT domain DUF3340 PF11818.3 EDO19286.1 - 0.2 11.5 3.7 2.2 8.2 1.4 2.3 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) Transp_cyt_pur PF02133.10 EDO19289.1 - 6e-174 578.7 35.2 6.9e-174 578.5 24.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Chitin_synth_2 PF03142.10 EDO19290.1 - 5.4e-270 896.2 0.1 7.5e-270 895.8 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EDO19290.1 - 1.1e-15 57.8 5.0 6.3e-15 55.3 3.5 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDO19290.1 - 5.5e-14 52.5 0.0 6.8e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EDO19290.1 - 7.4e-05 22.4 0.1 0.089 12.5 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EDO19290.1 - 0.00019 20.7 0.1 0.00061 19.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EDO19290.1 - 0.0002 21.0 0.0 0.026 14.2 0.0 3.3 3 0 0 3 3 3 1 Glycosyl transferase family 2 Chitin_synth_1 PF01644.12 EDO19291.1 - 4e-77 257.6 0.5 6.6e-77 256.8 0.3 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EDO19291.1 - 1.6e-24 86.1 4.6 8.1e-19 67.3 0.0 3.0 2 1 1 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 EDO19291.1 - 1.8e-24 85.2 0.1 4.8e-24 83.8 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EDO19291.1 - 4.6e-11 42.7 0.2 4.6e-11 42.7 0.2 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EDO19291.1 - 1.5e-09 37.9 0.0 2.1e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF2576 PF10845.3 EDO19291.1 - 0.081 12.1 0.4 0.27 10.4 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) YchF-GTPase_C PF06071.8 EDO19292.1 - 9.3e-38 127.8 0.2 5.2e-37 125.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EDO19292.1 - 1.4e-12 47.6 0.0 3.6e-12 46.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EDO19292.1 - 0.00034 20.4 0.0 0.00086 19.0 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EDO19292.1 - 0.0099 15.1 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 EDO19292.1 - 0.019 14.6 0.3 6.2 6.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Cupin_2 PF07883.6 EDO19292.1 - 0.069 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Dna2 PF08696.6 EDO19292.1 - 0.091 12.0 0.1 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 DNA replication factor Dna2 AAA_23 PF13476.1 EDO19292.1 - 0.28 11.4 4.1 1.8 8.8 2.8 2.1 1 1 0 1 1 1 0 AAA domain ADH_zinc_N PF00107.21 EDO19293.1 - 4.4e-05 23.0 0.0 7.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DRIM PF07539.7 EDO19294.1 - 1.7e-49 166.8 0.5 2.2e-48 163.2 0.3 3.3 2 0 0 2 2 2 1 Down-regulated in metastasis UNC45-central PF11701.3 EDO19294.1 - 0.00068 19.3 0.1 0.00068 19.3 0.1 4.8 6 0 0 6 6 6 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EDO19294.1 - 0.017 15.4 0.2 3.4 8.0 0.0 4.9 6 0 0 6 6 6 0 HEAT repeats HEAT PF02985.17 EDO19294.1 - 0.034 14.2 2.0 53 4.2 0.0 6.3 6 0 0 6 6 6 0 HEAT repeat Arm PF00514.18 EDO19294.1 - 0.09 12.6 2.2 3.6 7.5 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF77 PF01910.12 EDO19295.1 - 1.4e-29 101.5 0.1 1.6e-29 101.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Trehalase PF01204.13 EDO19296.1 - 3e-187 623.3 0.1 3.6e-187 623.0 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EDO19296.1 - 5.8e-17 60.7 1.1 1e-16 59.8 0.7 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Propep_M14 PF02244.11 EDO19296.1 - 0.057 13.0 0.1 0.21 11.2 0.1 2.0 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Prenyltransf PF01255.14 EDO19297.1 - 5.9e-79 264.3 0.0 7.4e-79 263.9 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase polyprenyl_synt PF00348.12 EDO19298.1 - 4.2e-52 176.5 0.0 2.1e-47 161.1 0.0 3.1 2 1 0 2 2 2 2 Polyprenyl synthetase RCR PF12273.3 EDO19299.1 - 5.7e-39 133.6 0.1 8.1e-39 133.1 0.1 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Rad51 PF08423.6 EDO19300.1 - 1e-29 103.2 0.0 1.3e-27 96.3 0.0 2.2 2 0 0 2 2 2 2 Rad51 RecA PF00154.16 EDO19300.1 - 1.3e-07 30.9 0.3 7.1e-07 28.5 0.2 2.0 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 EDO19300.1 - 3e-07 30.0 0.0 5.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EDO19300.1 - 1.3e-05 24.4 1.2 4.6e-05 22.6 0.8 1.9 1 1 0 1 1 1 1 KaiC Sel1 PF08238.7 EDO19301.1 - 1.3e-08 35.2 5.7 0.00041 20.8 0.1 3.4 3 0 0 3 3 3 3 Sel1 repeat Histone PF00125.19 EDO19302.1 - 2.5e-15 56.3 0.2 3.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EDO19302.1 - 3.2e-05 23.8 0.1 5.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 EDO19302.1 - 4.4e-05 23.3 0.2 6.2e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EDO19302.1 - 5e-05 23.3 0.1 7e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EDO19302.1 - 0.0012 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EDO19302.1 - 0.0042 16.7 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EDO19302.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 EDO19302.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EDO19303.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EDO19303.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDO19303.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EDO19303.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Pyrophosphatase PF00719.14 EDO19304.1 - 5.9e-54 181.7 0.4 8.5e-54 181.2 0.3 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Mannosyl_trans3 PF11051.3 EDO19305.1 - 6.6e-87 291.2 0.0 1.6e-86 290.0 0.0 1.7 1 0 0 1 1 1 1 Mannosyltransferase putative Tim54 PF11711.3 EDO19305.1 - 1.9 6.9 6.9 3.3 6.2 4.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CYSTM PF12734.2 EDO19306.1 - 0.27 11.3 70.0 1.5e+04 -25.2 48.5 4.6 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance zf-C3HC4 PF00097.20 EDO19307.1 - 0.0006 19.4 1.3 0.0016 18.0 0.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO19307.1 - 0.0038 17.0 0.1 0.012 15.4 0.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EDO19307.1 - 0.0048 16.8 2.0 0.0048 16.8 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO19307.1 - 0.0064 16.1 6.0 0.018 14.7 4.2 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EDO19307.1 - 7 6.5 9.7 0.45 10.3 2.5 2.1 2 0 0 2 2 2 0 Ring finger domain Use1 PF09753.4 EDO19308.1 - 4.1e-07 29.7 2.6 1.4e-06 27.9 1.8 1.9 1 1 0 1 1 1 1 Membrane fusion protein Use1 SRP54_N PF02881.14 EDO19308.1 - 0.015 15.3 4.3 0.9 9.6 0.1 3.0 2 1 1 3 3 3 0 SRP54-type protein, helical bundle domain F-protein PF00469.15 EDO19308.1 - 0.43 9.9 4.9 0.5 9.7 0.3 2.1 1 1 1 2 2 2 0 Negative factor, (F-Protein) or Nef Bystin PF05291.6 EDO19309.1 - 3.3e-123 410.4 0.0 4.9e-123 409.8 0.0 1.2 1 0 0 1 1 1 1 Bystin Arrestin_N PF00339.24 EDO19310.1 - 6.4e-05 22.8 0.8 0.00031 20.5 0.2 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Homeobox_KN PF05920.6 EDO19311.1 - 1.8e-19 69.1 0.7 6e-19 67.4 0.5 2.0 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EDO19311.1 - 1e-06 28.2 3.4 1.8e-06 27.4 0.5 2.3 2 0 0 2 2 2 1 Homeobox domain Avl9 PF09794.4 EDO19312.1 - 3.2e-150 499.8 1.4 3.2e-150 499.8 1.0 1.7 2 0 0 2 2 2 1 Transport protein Avl9 SPA PF08616.5 EDO19312.1 - 1.2e-06 28.1 3.9 0.02 14.5 0.1 3.2 2 1 1 3 3 3 2 Stabilization of polarity axis DENN PF02141.16 EDO19312.1 - 0.0046 16.7 0.7 0.18 11.4 0.5 2.5 1 1 0 1 1 1 1 DENN (AEX-3) domain efThoc1 PF11957.3 EDO19313.1 - 2.2e-122 409.0 23.9 2.2e-122 409.0 16.6 1.9 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor CPSF100_C PF13299.1 EDO19314.1 - 7e-31 107.5 0.5 7e-31 107.5 0.4 3.0 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EDO19314.1 - 1.7e-09 37.6 0.1 4.4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Rep_fac-A_3 PF08661.6 EDO19314.1 - 0.015 15.1 0.1 0.094 12.6 0.1 2.3 2 0 0 2 2 2 0 Replication factor A protein 3 zf-CCHC PF00098.18 EDO19315.1 - 2.4e-07 30.3 10.1 0.0014 18.4 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EDO19315.1 - 4.6e-07 29.4 10.1 0.00044 19.9 1.0 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EDO19315.1 - 3e-05 23.5 0.0 6.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EDO19315.1 - 9.6e-05 21.9 0.1 0.00021 20.8 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EDO19315.1 - 0.034 13.8 6.7 1.5 8.5 0.5 2.5 2 0 0 2 2 2 0 Zinc knuckle Collagen PF01391.13 EDO19315.1 - 0.23 11.0 3.1 0.63 9.6 2.2 1.8 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) zf-CCHC_6 PF15288.1 EDO19315.1 - 0.61 9.7 5.7 0.93 9.2 0.1 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.1 EDO19315.1 - 2.3 7.7 7.3 0.64 9.5 0.7 2.5 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger TPR_14 PF13428.1 EDO19316.1 - 1e-16 59.8 0.0 0.11 13.1 0.0 9.5 6 2 4 10 10 10 3 Tetratricopeptide repeat HAT PF02184.11 EDO19316.1 - 5.7e-15 54.7 25.9 0.014 15.1 0.0 8.9 8 0 0 8 8 8 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 EDO19316.1 - 9.4e-09 35.4 0.1 0.13 12.6 0.0 6.3 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 EDO19316.1 - 1.1e-07 32.2 0.0 0.036 14.7 0.0 6.4 6 1 0 6 6 6 1 Tetratricopeptide repeat Suf PF05843.9 EDO19316.1 - 3.6e-06 26.9 14.4 0.073 12.7 0.3 6.4 2 1 4 6 6 6 3 Suppressor of forked protein (Suf) U3_assoc_6 PF08640.6 EDO19316.1 - 0.00046 19.8 10.6 0.0057 16.3 0.3 5.4 4 2 1 5 5 5 1 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.1 EDO19316.1 - 0.00062 19.6 0.0 12 5.9 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EDO19316.1 - 0.0022 18.0 0.9 0.26 11.5 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO19316.1 - 0.0025 17.5 4.1 18 5.5 0.0 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_9 PF13371.1 EDO19316.1 - 0.025 14.4 0.0 0.43 10.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EDO19316.1 - 0.094 12.4 8.9 0.72 9.6 0.8 4.6 5 1 1 6 6 6 0 Mad3/BUB1 homology region 1 DUF717 PF05338.7 EDO19316.1 - 0.11 12.5 0.0 2.2 8.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF717) ubiquitin PF00240.18 EDO19317.1 - 2.2e-23 81.4 1.7 2.4e-23 81.3 1.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EDO19317.1 - 4.5e-17 61.5 0.7 4.9e-17 61.3 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EDO19317.1 - 0.00015 21.9 0.2 0.00049 20.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 EDO19317.1 - 0.095 12.9 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain SUI1 PF01253.17 EDO19317.1 - 0.097 12.4 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor SUI1 Methyltransf_26 PF13659.1 EDO19318.1 - 3.6e-13 49.5 0.0 5.2e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EDO19318.1 - 9.1e-07 28.4 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EDO19318.1 - 1.5e-05 24.5 0.0 2.1e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EDO19318.1 - 0.0015 17.7 0.1 0.0031 16.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EDO19318.1 - 0.0041 17.5 0.0 0.036 14.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO19318.1 - 0.0049 16.6 0.0 0.094 12.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain OpuAC PF04069.7 EDO19318.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Dopey_N PF04118.9 EDO19319.1 - 1.3e-117 391.9 1.5 1.3e-117 391.9 1.0 4.7 5 0 0 5 5 5 3 Dopey, N-terminal WD40 PF00400.27 EDO19320.1 - 3.4e-28 96.4 14.9 4.7e-07 29.4 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-RING_2 PF13639.1 EDO19321.1 - 5.7e-11 42.0 5.5 4.7e-10 39.1 1.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EDO19321.1 - 9.5e-08 32.0 1.8 3.5e-06 27.0 0.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EDO19321.1 - 2.7e-05 24.1 6.2 4.6e-05 23.3 1.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EDO19321.1 - 0.00013 21.6 1.4 0.00041 19.9 0.6 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EDO19321.1 - 0.00024 20.7 3.3 0.00063 19.3 0.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO19321.1 - 0.00031 20.3 3.6 0.00032 20.2 1.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EDO19321.1 - 0.00034 20.4 1.9 0.00034 20.4 1.3 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EDO19321.1 - 0.0004 20.0 3.1 0.00082 19.0 0.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EDO19321.1 - 0.0092 15.7 1.7 0.027 14.2 0.7 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Cullin_binding PF03556.10 EDO19322.1 - 4.9e-29 100.8 4.9 1.2e-28 99.5 3.4 1.7 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EDO19322.1 - 2.1e-12 46.3 0.0 4.4e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain TCTP PF00838.12 EDO19322.1 - 0.053 13.5 1.0 0.082 12.8 0.2 1.6 2 0 0 2 2 2 0 Translationally controlled tumour protein WD40 PF00400.27 EDO19323.1 - 4.8e-76 248.1 20.8 4.4e-08 32.7 0.4 11.6 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.7 EDO19323.1 - 2e-25 88.8 1.1 3.8e-25 87.9 0.7 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EDO19323.1 - 1.1e-07 30.4 13.6 0.0071 14.5 0.2 5.7 4 3 0 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDO19323.1 - 0.00015 20.6 17.3 0.4 9.3 0.0 6.5 2 2 3 6 6 6 3 Nup133 N terminal like Pex14_N PF04695.8 EDO19323.1 - 0.058 13.4 0.3 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hira PF07569.6 EDO19323.1 - 0.089 11.9 4.4 5.3 6.2 0.0 4.8 6 1 0 6 6 6 0 TUP1-like enhancer of split zf-C2H2 PF00096.21 EDO19324.1 - 4.1e-09 36.2 20.0 0.00054 20.1 1.5 3.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO19324.1 - 1.1e-07 31.8 13.9 0.00015 21.8 0.1 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO19324.1 - 2.6e-06 27.3 10.4 0.015 15.5 1.0 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EDO19324.1 - 0.0089 16.1 8.9 1.6 8.9 0.3 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EDO19324.1 - 0.02 15.2 1.8 0.02 15.2 1.3 1.9 1 1 1 2 2 2 0 TRAF-type zinc finger Bunya_G2 PF03563.8 EDO19324.1 - 0.031 13.1 0.5 0.049 12.4 0.4 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 RFX5_DNA_bdg PF14621.1 EDO19324.1 - 0.037 13.6 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 RFX5 DNA-binding domain zf-C2H2_6 PF13912.1 EDO19324.1 - 0.17 11.8 10.8 0.47 10.4 0.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 EDO19324.1 - 0.52 10.5 2.2 16 5.8 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HVSL PF09749.4 EDO19325.1 - 2e-53 180.8 1.6 2.6e-53 180.5 1.1 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Staphostatin_A PF09022.5 EDO19325.1 - 0.01 15.6 0.5 0.045 13.5 0.2 2.2 2 1 1 3 3 3 0 Staphostatin A EAP30 PF04157.11 EDO19325.1 - 0.095 11.8 0.1 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family Choline_kinase PF01633.15 EDO19326.1 - 1.6e-64 217.3 0.0 2.3e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EDO19326.1 - 4.3e-17 61.3 0.0 1e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EDO19326.1 - 5.1e-09 36.2 0.0 0.00054 19.7 0.0 2.5 2 1 0 2 2 2 2 Phosphotransferase enzyme family Slx4 PF09494.5 EDO19327.1 - 2.6e-15 55.9 0.1 6.6e-15 54.6 0.1 1.8 1 0 0 1 1 1 1 Slx4 endonuclease DUF4351 PF14261.1 EDO19327.1 - 0.016 15.0 1.3 11 5.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) Peptidase_M28 PF04389.12 EDO19328.1 - 1.6e-15 57.3 0.0 2.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EDO19328.1 - 9e-11 41.4 0.0 1.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EDO19328.1 - 3.7e-06 26.5 0.1 8.2e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EDO19328.1 - 0.0005 19.6 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EDO19328.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Nicastrin RWD PF05773.17 EDO19329.1 - 1.9e-21 76.0 7.5 1.9e-21 76.0 5.2 2.2 2 1 0 2 2 2 1 RWD domain UEV PF05743.8 EDO19329.1 - 0.0015 18.1 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain DUF4390 PF14334.1 EDO19329.1 - 0.057 12.6 0.1 0.25 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) ENTH PF01417.15 EDO19330.1 - 1.6e-33 115.2 0.5 1.6e-33 115.2 0.4 1.8 2 0 0 2 2 2 1 ENTH domain RNA_polI_A14 PF08203.6 EDO19331.1 - 1.7e-25 89.0 0.2 1.7e-25 89.0 0.1 1.9 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 MTBP_C PF14920.1 EDO19331.1 - 0.0041 16.6 1.7 0.0048 16.4 1.2 1.2 1 0 0 1 1 1 1 MDM2-binding DUF1117 PF06547.7 EDO19331.1 - 0.12 12.5 3.1 0.18 11.8 1.5 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1117) AATF-Che1 PF13339.1 EDO19331.1 - 0.47 10.6 3.4 1.1 9.3 2.0 1.8 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor SR-25 PF10500.4 EDO19331.1 - 1.7 8.1 9.3 2 7.8 6.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3446 PF11928.3 EDO19331.1 - 1.7 8.8 11.3 1.2 9.3 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) SAC3_GANP PF03399.11 EDO19332.1 - 1.6e-58 197.6 0.3 9e-58 195.1 0.0 2.2 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAC3 PF12209.3 EDO19332.1 - 2e-27 95.1 2.2 6.2e-27 93.5 1.5 1.9 1 0 0 1 1 1 1 Leucine permease transcriptional regulator helical domain ING PF12998.2 EDO19333.1 - 0.23 11.7 3.1 0.2 11.9 0.9 1.8 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding SPACA7 PF15307.1 EDO19333.1 - 0.77 9.9 4.2 0.28 11.3 0.7 2.0 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 Nha1_C PF08619.5 EDO19334.1 - 1.9e-108 363.5 25.5 2.3e-108 363.2 17.6 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EDO19334.1 - 9.2e-76 254.8 25.6 1.1e-75 254.5 17.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TPR_11 PF13414.1 EDO19335.1 - 0.00037 20.0 1.0 0.7 9.5 0.0 3.8 3 1 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 EDO19335.1 - 0.00041 20.6 0.2 0.07 13.4 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EDO19335.1 - 0.00045 19.9 4.2 1.3 9.1 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EDO19335.1 - 0.0039 17.8 0.0 2.7 8.7 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EDO19335.1 - 0.023 14.6 0.1 4.3 7.3 0.0 3.4 4 2 1 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EDO19335.1 - 0.059 13.5 2.1 6 7.0 0.0 3.3 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EDO19335.1 - 0.066 13.8 0.0 44 5.1 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EDO19335.1 - 0.15 11.7 5.0 26 4.6 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SLS PF14611.1 EDO19336.1 - 2.7e-23 82.4 1.5 2.8e-23 82.4 0.2 1.7 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator OEP PF02321.13 EDO19336.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein Pro_dh PF01619.13 EDO19338.1 - 3.5e-61 206.8 0.0 4.7e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase ATP_bind_4 PF01902.12 EDO19339.1 - 9.2e-33 113.4 0.0 2.9e-32 111.8 0.0 1.8 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 EDO19339.1 - 1.8e-20 72.9 0.0 6.9e-14 51.6 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP Sec1 PF00995.18 EDO19341.1 - 9.7e-108 361.2 1.0 9.7e-108 361.2 0.7 1.9 2 0 0 2 2 2 1 Sec1 family CDK5_activator PF03261.10 EDO19341.1 - 0.35 10.1 12.4 0.84 8.9 8.6 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein Ndc1_Nup PF09531.5 EDO19341.1 - 4.3 5.6 7.1 6.4 5.0 4.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup BAF1_ABF1 PF04684.8 EDO19341.1 - 6.3 5.5 19.6 11 4.7 13.6 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_hydro_81 PF03639.8 EDO19342.1 - 1.4e-130 436.5 19.6 1.7e-130 436.2 13.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 WD40 PF00400.27 EDO19343.1 - 5.8e-05 22.8 3.0 0.0018 18.0 1.1 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.10 EDO19343.1 - 8.4e-05 21.8 0.5 0.00019 20.6 0.1 1.7 2 0 0 2 2 2 1 CPSF A subunit region LSM PF01423.17 EDO19344.1 - 4.7e-13 48.4 0.4 5.9e-13 48.1 0.3 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EDO19344.1 - 0.095 12.6 0.2 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain Pep3_Vps18 PF05131.9 EDO19345.1 - 8.6e-37 125.8 0.1 1.9e-36 124.6 0.1 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EDO19345.1 - 1.5e-09 37.6 3.8 1.5e-09 37.6 2.6 4.1 4 1 0 4 4 4 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 EDO19345.1 - 1.6e-05 24.6 1.9 3.8e-05 23.4 1.3 1.7 1 0 0 1 1 1 1 Ring finger domain Vps39_2 PF10367.4 EDO19345.1 - 0.00017 21.7 0.2 0.00017 21.7 0.2 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 EDO19345.1 - 0.001 18.7 8.7 0.0059 16.3 6.0 2.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EDO19345.1 - 0.0023 17.9 3.1 0.015 15.2 0.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO19345.1 - 0.03 13.9 4.7 0.023 14.3 0.9 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EDO19345.1 - 8.2 6.1 8.3 67 3.2 5.7 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2415 PF10313.4 EDO19346.1 - 3.1e-22 77.9 0.2 1e-21 76.3 0.1 2.0 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Stb3 PF10330.4 EDO19347.1 - 2.3e-29 100.9 0.0 4.6e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein PRP1_N PF06424.7 EDO19347.1 - 1.4 9.2 6.6 6.8 7.0 0.4 2.6 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Stm1_N PF09598.5 EDO19348.1 - 1.4e-14 54.5 1.7 1.4e-14 54.5 1.2 3.0 3 0 0 3 3 3 1 Stm1 HABP4_PAI-RBP1 PF04774.10 EDO19348.1 - 0.56 10.7 12.5 0.057 13.9 4.4 2.3 1 1 1 2 2 2 0 Hyaluronan / mRNA binding family Tropomyosin_1 PF12718.2 EDO19348.1 - 0.67 9.7 9.1 1.3 8.8 6.3 1.4 1 0 0 1 1 1 0 Tropomyosin like NUDIX PF00293.23 EDO19349.1 - 1.7e-15 56.8 0.0 1.3e-14 53.9 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain Sec7 PF01369.15 EDO19350.1 - 5.2e-67 225.2 0.2 2.8e-66 222.8 0.1 2.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EDO19350.1 - 1.2e-54 184.2 0.7 1.2e-54 184.2 0.5 4.5 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EDO19350.1 - 2e-30 104.1 6.9 8.2e-29 98.9 0.5 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) SDA1 PF05285.7 EDO19350.1 - 3.3 6.9 76.3 0.093 11.9 39.3 2.5 2 0 0 2 2 2 0 SDA1 DUF3584 PF12128.3 EDO19351.1 - 0.0018 15.7 25.2 0.0021 15.4 17.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Sigma54_AID PF00309.15 EDO19351.1 - 0.33 10.4 7.3 0.83 9.1 0.9 3.3 3 0 0 3 3 3 0 Sigma-54 factor, Activator interacting domain (AID) Lipoprotein_20 PF13942.1 EDO19351.1 - 1.8 8.0 19.6 0.63 9.5 10.2 2.1 1 1 1 2 2 2 0 YfhG lipoprotein rve PF00665.21 EDO19353.1 - 3e-17 62.8 0.0 4.4e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain DDE_Tnp_IS240 PF13610.1 EDO19353.1 - 0.03 14.2 0.0 0.046 13.6 0.0 1.2 1 0 0 1 1 1 0 DDE domain GDC-P PF02347.11 EDO19354.1 - 0.07 11.8 0.5 0.089 11.4 0.3 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Xpo1 PF08389.7 EDO19354.1 - 0.12 12.3 0.9 0.17 11.8 0.6 1.3 1 0 0 1 1 1 0 Exportin 1-like protein FTR_C PF02741.10 EDO19354.1 - 0.13 12.0 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 FTR, proximal lobe DUF4359 PF14271.1 EDO19354.1 - 0.14 12.4 0.4 0.49 10.7 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4359) Sp38 PF07354.7 EDO19354.1 - 0.17 10.4 2.8 0.25 9.9 1.9 1.2 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) Chlam_vir PF05475.6 EDO19354.1 - 0.39 9.7 2.3 0.45 9.5 1.6 1.1 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D GTP_EFTU PF00009.22 EDO19355.1 - 3.6e-47 160.2 0.0 1.1e-46 158.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EDO19355.1 - 4.1e-23 81.4 0.6 4.1e-23 81.4 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EDO19355.1 - 3.1e-07 30.4 0.4 7.9e-07 29.1 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EDO19355.1 - 0.00014 21.8 0.0 0.00055 19.8 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF4551 PF15087.1 EDO19355.1 - 2 6.6 12.6 2.9 6.1 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.5 EDO19355.1 - 4.7 5.5 6.1 6.3 5.1 4.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_L31e PF01198.14 EDO19356.1 - 1.5e-35 120.7 1.4 1.7e-35 120.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e DUF1765 PF08578.5 EDO19357.1 - 1.7e-25 89.4 9.6 1.7e-25 89.4 6.7 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) TFIIA PF03153.8 EDO19359.1 - 1.7e-06 28.2 35.5 2.6e-06 27.6 24.6 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nucleoplasmin PF03066.10 EDO19359.1 - 0.00018 21.0 3.0 0.00046 19.7 2.1 1.7 1 0 0 1 1 1 1 Nucleoplasmin zf-C2H2_4 PF13894.1 EDO19359.1 - 0.0031 17.7 23.6 0.035 14.4 0.3 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO19359.1 - 0.024 14.8 21.6 0.029 14.6 0.8 4.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.21 EDO19359.1 - 0.054 13.8 1.3 0.054 13.8 0.9 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EDO19359.1 - 0.094 12.8 0.1 0.094 12.8 0.0 5.5 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding SprA-related PF12118.3 EDO19359.1 - 9.2 5.4 33.0 8 5.6 18.6 2.1 2 0 0 2 2 2 0 SprA-related family Zn_clus PF00172.13 EDO19360.1 - 1.6e-09 37.4 14.3 2.8e-09 36.7 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGP PF01704.13 EDO19361.1 - 3.3e-191 635.3 0.0 4.2e-191 634.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase zf-RING_2 PF13639.1 EDO19362.1 - 2.8e-11 43.0 4.7 6.4e-11 41.9 3.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EDO19362.1 - 1.3e-08 34.8 4.0 2.6e-08 33.8 2.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EDO19362.1 - 4.7e-08 32.6 2.5 8.4e-08 31.8 1.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EDO19362.1 - 1.5e-06 27.7 3.1 3e-06 26.7 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EDO19362.1 - 2.2e-06 27.1 4.3 4.5e-06 26.2 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO19362.1 - 2.5e-05 24.1 5.2 0.00014 21.8 3.6 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EDO19362.1 - 0.001 18.8 1.7 0.0025 17.6 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EDO19362.1 - 0.027 14.2 1.0 0.08 12.6 0.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EDO19362.1 - 0.032 14.0 1.0 0.065 13.0 0.2 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein FANCL_C PF11793.3 EDO19362.1 - 0.059 13.3 5.3 0.26 11.2 3.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain BRAP2 PF07576.7 EDO19363.1 - 1.2e-26 92.4 2.6 7.3e-26 89.9 1.0 2.6 3 0 0 3 3 3 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EDO19363.1 - 4.9e-22 77.8 7.1 1.5e-21 76.2 5.0 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EDO19363.1 - 5.4e-11 42.1 9.8 5.4e-11 42.1 6.8 2.2 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EDO19363.1 - 5.8e-06 25.8 6.0 5.8e-06 25.8 4.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EDO19363.1 - 7.9e-06 25.8 9.6 7.9e-06 25.8 6.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EDO19363.1 - 8.8e-06 25.3 8.2 8.8e-06 25.3 5.7 2.5 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EDO19363.1 - 8.8e-06 25.2 9.4 8.8e-06 25.2 6.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EDO19363.1 - 0.00013 22.0 4.4 0.00013 22.0 3.1 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EDO19363.1 - 0.0011 18.6 4.6 0.0017 18.0 2.0 2.4 1 1 0 1 1 1 1 RING-type zinc-finger HOOK PF05622.7 EDO19363.1 - 0.0022 15.9 14.1 0.0031 15.3 9.8 1.2 1 0 0 1 1 1 1 HOOK protein Baculo_RING PF05883.6 EDO19363.1 - 0.0043 16.8 1.6 0.013 15.2 1.1 1.9 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain zf-Apc11 PF12861.2 EDO19363.1 - 0.0084 15.9 4.2 0.0084 15.9 2.9 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_2 PF04059.7 EDO19363.1 - 0.011 15.7 0.3 0.044 13.7 0.2 2.0 2 0 0 2 2 2 0 RNA recognition motif 2 Baculo_PEP_C PF04513.7 EDO19363.1 - 0.02 14.6 5.1 0.04 13.7 3.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EDO19363.1 - 0.042 13.6 8.4 0.052 13.3 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_4 PF14570.1 EDO19363.1 - 0.073 12.6 7.9 0.19 11.3 5.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IncA PF04156.9 EDO19363.1 - 0.16 11.5 14.8 0.33 10.5 10.2 1.5 1 0 0 1 1 1 0 IncA protein DUF4407 PF14362.1 EDO19363.1 - 0.45 9.4 3.8 0.73 8.7 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cep57_MT_bd PF06657.8 EDO19363.1 - 0.88 9.5 13.4 0.82 9.6 3.8 2.8 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 FlaC_arch PF05377.6 EDO19363.1 - 2.8 7.9 8.2 1.8 8.5 0.2 3.1 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Form_Nir_trans PF01226.12 EDO19364.1 - 6.3e-64 215.2 19.2 7.8e-64 214.9 13.3 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter DUF585 PF04522.7 EDO19364.1 - 0.011 15.1 0.9 0.02 14.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF585) HEAT PF02985.17 EDO19365.1 - 0.00026 20.7 0.3 5.6 7.3 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EDO19365.1 - 0.0055 16.9 0.0 3.7 7.8 0.0 4.4 4 0 0 4 4 4 1 HEAT repeats PHD PF00628.24 EDO19366.1 - 2.6e-15 55.8 19.4 2.6e-11 43.0 5.1 3.1 2 1 1 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.1 EDO19366.1 - 0.002 18.2 0.5 0.002 18.2 0.4 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain C1_1 PF00130.17 EDO19366.1 - 0.0093 15.6 8.9 0.27 10.9 0.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PRCC PF10253.4 EDO19366.1 - 0.017 15.8 3.7 0.017 15.8 2.6 2.6 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting zf-PHD-like PF15446.1 EDO19366.1 - 0.089 12.0 5.8 0.8 8.9 0.1 2.8 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EDO19366.1 - 0.38 10.1 8.9 0.91 8.8 0.2 3.3 3 0 0 3 3 3 0 PHD-finger Prok-RING_1 PF14446.1 EDO19366.1 - 4.2 7.1 11.9 0.21 11.3 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 dsDNA_bind PF01984.15 EDO19367.1 - 3.1e-27 94.6 0.0 3.8e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain GDC-P PF02347.11 EDO19368.1 - 5.8e-190 631.5 0.0 1.5e-177 590.6 0.0 2.7 2 1 0 2 2 2 2 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.15 EDO19368.1 - 6.9e-05 21.2 0.1 0.0032 15.8 0.0 2.7 3 0 0 3 3 3 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EDO19368.1 - 0.00022 20.1 0.1 0.0006 18.6 0.1 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EDO19368.1 - 0.00094 18.3 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Ribosomal_S17 PF00366.15 EDO19369.1 - 3.4e-14 52.6 1.3 4e-14 52.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 Phage_XkdX PF09693.5 EDO19369.1 - 0.079 12.4 0.5 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) Rhomboid PF01694.17 EDO19370.1 - 1e-18 67.7 12.8 1e-18 67.7 8.9 1.7 2 0 0 2 2 2 1 Rhomboid family HSP90 PF00183.13 EDO19371.1 - 3.7e-255 847.3 40.0 4.3e-255 847.1 27.7 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EDO19371.1 - 1.6e-11 43.8 0.0 2.9e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EDO19371.1 - 1.5e-10 40.8 0.0 1.5e-10 40.8 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 EDO19371.1 - 0.42 9.9 25.5 0.097 12.0 11.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DDHD PF02862.12 EDO19371.1 - 3.7 7.2 12.6 3.6 7.3 4.4 2.4 2 0 0 2 2 2 0 DDHD domain DUF2435 PF10363.4 EDO19372.1 - 1.9e-28 98.1 0.6 1.9e-28 98.1 0.4 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EDO19372.1 - 5e-06 25.8 0.4 2e-05 23.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2411) HEAT_2 PF13646.1 EDO19372.1 - 0.0047 17.1 0.0 0.88 9.8 0.0 3.0 3 0 0 3 3 3 1 HEAT repeats Ank_4 PF13637.1 EDO19373.1 - 3.4e-18 65.6 0.2 9.5e-13 48.2 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDO19373.1 - 3.6e-17 61.9 1.7 7.1e-10 38.8 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EDO19373.1 - 6.5e-17 61.6 0.3 1.4e-16 60.5 0.2 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EDO19373.1 - 6.4e-16 57.2 0.7 2.7e-08 33.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EDO19373.1 - 2.7e-13 48.7 0.2 1.1e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat PqqD PF05402.7 EDO19373.1 - 0.079 12.9 1.3 1.4 8.9 0.0 2.6 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) PRANC PF09372.5 EDO19374.1 - 0.024 14.5 0.5 0.069 13.1 0.0 2.0 2 0 0 2 2 2 0 PRANC domain Pkinase PF00069.20 EDO19375.1 - 1.4e-24 86.6 1.8 2.4e-19 69.5 0.3 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EDO19375.1 - 1.5e-17 63.5 0.4 7.1e-13 48.2 0.0 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase DUF3989 PF13150.1 EDO19376.1 - 0.068 12.6 0.0 0.068 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) SNARE PF05739.14 EDO19377.1 - 4.9e-14 51.7 9.7 4.9e-14 51.7 6.7 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EDO19377.1 - 1.8e-07 31.2 20.7 2.1e-06 27.8 5.0 2.5 2 1 0 2 2 2 2 Syntaxin T2SF PF00482.18 EDO19377.1 - 0.0039 17.0 0.2 0.0093 15.8 0.1 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Synaptobrevin PF00957.16 EDO19377.1 - 0.0042 16.6 2.7 0.0042 16.6 1.9 2.7 2 1 0 2 2 2 1 Synaptobrevin DUF2562 PF10814.3 EDO19377.1 - 0.036 14.0 1.8 0.052 13.5 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2562) BLOC1_2 PF10046.4 EDO19377.1 - 0.064 13.3 0.3 0.064 13.3 0.2 3.3 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3708 PF12501.3 EDO19377.1 - 0.094 12.5 4.6 0.069 12.9 0.8 2.2 1 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter PBP1_TM PF14812.1 EDO19377.1 - 0.15 12.3 1.2 0.63 10.3 0.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Herpes_US9 PF06072.6 EDO19377.1 - 0.15 11.8 2.3 0.32 10.8 1.6 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF4094 PF13334.1 EDO19377.1 - 0.32 11.4 0.1 0.32 11.4 0.1 3.2 2 1 1 4 4 4 0 Domain of unknown function (DUF4094) DUF3394 PF11874.3 EDO19377.1 - 0.41 10.1 3.5 0.47 9.9 1.1 2.2 1 1 1 3 3 3 0 Domain of unknown function (DUF3394) Syntaxin_2 PF14523.1 EDO19377.1 - 1.1 9.2 21.9 0.78 9.8 7.4 2.8 2 2 0 2 2 2 0 Syntaxin-like protein ACPS PF01648.15 EDO19378.1 - 1.2e-18 66.9 0.1 3e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ketoacyl-synt PF00109.21 EDO19378.1 - 7.1e-18 64.9 0.1 1.6e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EDO19378.1 - 3.7e-13 49.3 0.0 1e-12 47.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EDO19378.1 - 0.00018 21.4 0.0 0.00067 19.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EDO19378.1 - 0.029 14.0 0.0 0.098 12.3 0.0 1.9 1 0 0 1 1 1 0 KR domain zf-C2H2 PF00096.21 EDO19379.1 - 5.2e-10 39.0 9.2 0.00013 22.1 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EDO19379.1 - 1.4e-08 34.5 3.9 1.4e-08 34.5 2.7 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EDO19379.1 - 9.1e-08 31.9 7.1 0.00046 20.3 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EDO19379.1 - 0.0003 20.5 3.1 0.48 10.3 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EDO19379.1 - 0.0012 18.9 1.1 0.0012 18.9 0.7 3.1 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-BED PF02892.10 EDO19379.1 - 0.065 13.0 1.1 0.17 11.6 0.7 1.8 1 1 0 1 1 1 0 BED zinc finger GAGA PF09237.6 EDO19379.1 - 0.12 11.9 0.9 0.26 10.9 0.7 1.5 1 0 0 1 1 1 0 GAGA factor zf-met PF12874.2 EDO19379.1 - 0.33 11.2 2.5 0.36 11.1 0.5 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type mRNA_triPase PF02940.10 EDO19381.1 - 8.8e-60 202.1 0.9 8.8e-60 202.1 0.7 2.2 3 1 0 3 3 3 1 mRNA capping enzyme, beta chain ABC_tran PF00005.22 EDO19383.1 - 1.5e-48 164.6 4.0 1.4e-25 90.1 0.0 4.5 3 2 0 3 3 3 2 ABC transporter SMC_N PF02463.14 EDO19383.1 - 5.5e-14 51.9 0.0 0.00015 21.0 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EDO19383.1 - 1.2e-12 48.4 13.3 4.7e-05 23.5 0.2 5.1 3 2 0 3 3 3 2 AAA domain Chromo PF00385.19 EDO19383.1 - 2.4e-09 36.7 2.6 6.1e-09 35.4 1.8 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 EDO19383.1 - 2.1e-07 30.3 0.2 0.011 15.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 EDO19383.1 - 1.5e-06 27.5 0.2 0.064 12.2 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EDO19383.1 - 1.5e-06 27.4 0.0 0.0065 15.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDO19383.1 - 2.2e-06 28.4 0.3 0.12 13.2 0.0 3.5 3 1 0 3 3 2 2 AAA domain AAA_23 PF13476.1 EDO19383.1 - 2.3e-06 28.0 8.6 0.00097 19.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 EDO19383.1 - 2.5e-06 27.4 0.0 0.018 14.9 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EDO19383.1 - 4.2e-06 26.9 0.1 0.041 14.0 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EDO19383.1 - 7e-06 25.6 2.4 0.26 10.7 0.1 4.2 4 0 0 4 4 4 2 AAA-like domain Miro PF08477.8 EDO19383.1 - 3e-05 24.4 0.0 0.1 13.1 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 EDO19383.1 - 0.00013 21.6 0.1 0.17 11.5 0.0 2.7 2 0 0 2 2 2 2 NACHT domain MobB PF03205.9 EDO19383.1 - 0.00026 20.7 0.0 0.39 10.4 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EDO19383.1 - 0.0003 20.6 5.6 0.026 14.3 0.1 3.9 4 0 0 4 4 4 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 EDO19383.1 - 0.00034 20.7 0.1 1.4 9.1 0.0 3.0 2 0 0 2 2 2 2 RNA helicase ArgK PF03308.11 EDO19383.1 - 0.00035 19.4 0.1 0.51 9.0 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_28 PF13521.1 EDO19383.1 - 0.00049 20.0 0.0 0.21 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EDO19383.1 - 0.00053 19.8 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EDO19383.1 - 0.00062 19.6 3.6 1.6 8.6 0.0 4.8 4 2 1 5 5 4 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EDO19383.1 - 0.00063 19.3 0.6 3.1 7.3 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EDO19383.1 - 0.00066 19.9 1.3 0.14 12.5 0.0 3.3 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 EDO19383.1 - 0.003 17.2 0.1 3 7.4 0.0 2.8 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 EDO19383.1 - 0.0033 17.6 0.0 5.7 7.1 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EDO19383.1 - 0.0046 16.8 0.1 1.7 8.5 0.0 3.3 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EDO19383.1 - 0.01 15.6 0.4 1.3 8.8 0.0 3.5 3 1 0 3 3 2 0 Dynamin family AAA_16 PF13191.1 EDO19383.1 - 0.015 15.3 1.2 1.1 9.1 0.0 3.4 3 1 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.7 EDO19383.1 - 0.034 13.2 0.2 2.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 EDO19383.1 - 0.04 13.3 0.0 11 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EDO19383.1 - 0.042 13.2 0.2 17 4.7 0.0 3.4 4 0 0 4 4 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 EDO19383.1 - 0.044 13.4 0.2 5.2 6.7 0.1 2.8 3 0 0 3 3 3 0 NTPase Thymidylate_kin PF02223.12 EDO19383.1 - 0.059 12.7 0.4 0.67 9.2 0.0 2.7 3 0 0 3 3 2 0 Thymidylate kinase MutS_V PF00488.16 EDO19383.1 - 0.087 12.2 0.1 14 4.9 0.0 2.3 2 0 0 2 2 2 0 MutS domain V FtsK_SpoIIIE PF01580.13 EDO19383.1 - 0.092 12.2 0.2 6.2 6.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EDO19383.1 - 0.12 11.8 0.1 11 5.4 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MoCF_biosynth PF00994.19 EDO19384.1 - 1.3e-33 115.4 0.0 2e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF573 PF04504.9 EDO19384.1 - 0.069 13.4 0.0 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF573 DUF2683 PF10884.3 EDO19384.1 - 1.3 9.0 5.0 67 3.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2683) GCR1_C PF12550.3 EDO19385.1 - 3.3e-25 87.7 0.9 7.8e-25 86.5 0.6 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Daxx PF03344.10 EDO19385.1 - 0.00056 18.5 14.7 0.00056 18.5 10.2 2.3 2 0 0 2 2 2 1 Daxx Family DUF1515 PF07439.6 EDO19385.1 - 0.015 15.1 0.1 0.035 13.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) SlyX PF04102.7 EDO19385.1 - 0.18 12.2 1.4 0.74 10.2 1.0 2.2 1 0 0 1 1 1 0 SlyX UPF0061 PF02696.9 EDO19386.1 - 1.3e-161 538.2 0.8 1.6e-161 537.8 0.6 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF3422 PF11902.3 EDO19386.1 - 0.27 10.0 0.0 0.43 9.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) TRP PF06011.7 EDO19387.1 - 3.7e-106 355.3 36.8 4.9e-106 354.9 25.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EDO19387.1 - 3.8e-41 140.4 1.0 7.6e-41 139.4 0.7 1.5 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EDO19387.1 - 0.0051 17.0 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 ML domain Coatomer_WDAD PF04053.9 EDO19389.1 - 1.9e-165 550.9 0.5 2.4e-165 550.6 0.4 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 EDO19389.1 - 8e-25 85.7 3.2 3.9e-09 36.0 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat TPR_2 PF07719.12 EDO19389.1 - 0.00024 20.7 2.3 0.47 10.4 0.1 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EDO19389.1 - 0.00068 19.1 0.2 1.6 8.4 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EDO19389.1 - 0.0015 18.2 4.6 0.27 11.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Nup160 PF11715.3 EDO19389.1 - 0.0017 16.5 0.0 1.1 7.3 0.0 3.2 3 0 0 3 3 3 1 Nucleoporin Nup120/160 TPR_11 PF13414.1 EDO19389.1 - 0.0035 16.9 0.5 0.33 10.6 0.1 2.8 2 0 0 2 2 2 1 TPR repeat NAD_synthase PF02540.12 EDO19389.1 - 0.019 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD synthase FtsJ PF01728.14 EDO19390.1 - 2.8e-55 187.1 0.0 3.5e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EDO19390.1 - 0.002 17.8 0.0 0.0069 16.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO19390.1 - 0.016 14.8 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EDO19390.1 - 0.096 13.2 0.0 0.25 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_L1 PF00687.16 EDO19391.1 - 4.7e-45 153.6 1.6 5.7e-45 153.3 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Vesiculo_matrix PF06326.7 EDO19391.1 - 0.12 11.8 0.1 0.52 9.7 0.0 1.8 2 0 0 2 2 2 0 Vesiculovirus matrix protein Arf PF00025.16 EDO19392.1 - 2.1e-66 222.4 0.0 2.4e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EDO19392.1 - 1.3e-09 38.6 0.0 1.9e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EDO19392.1 - 1.6e-09 37.3 0.0 2.1e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EDO19392.1 - 5.3e-09 35.2 1.1 5.9e-06 25.2 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EDO19392.1 - 2.4e-08 33.4 0.0 3.1e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EDO19392.1 - 3.9e-06 26.8 0.0 5.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EDO19392.1 - 4.5e-05 22.6 0.0 5.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EDO19392.1 - 0.00036 20.0 0.1 0.0062 15.9 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EDO19392.1 - 0.043 13.2 0.0 0.15 11.5 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF663 PF04950.7 EDO19393.1 - 2.4e-103 345.2 0.0 2.4e-103 345.2 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EDO19393.1 - 6.9e-29 99.2 0.0 2.3e-28 97.5 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EDO19393.1 - 9.8e-08 31.6 0.0 6.9e-05 22.3 0.0 2.7 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain MobB PF03205.9 EDO19393.1 - 3.3e-05 23.6 0.3 0.00028 20.6 0.2 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EDO19393.1 - 3.4e-05 24.0 0.0 0.00012 22.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EDO19393.1 - 3.7e-05 23.3 0.1 9.4e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EDO19393.1 - 7.3e-05 22.9 0.0 0.00021 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EDO19393.1 - 8.5e-05 22.6 0.0 0.00025 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EDO19393.1 - 0.00017 22.4 0.0 0.00017 22.4 0.0 4.4 3 1 0 3 3 1 1 AAA domain AAA_33 PF13671.1 EDO19393.1 - 0.00025 20.9 0.0 0.0013 18.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EDO19393.1 - 0.00027 21.4 0.0 0.0013 19.1 0.0 2.4 2 0 0 2 2 1 1 Miro-like protein NACHT PF05729.7 EDO19393.1 - 0.0024 17.5 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 EDO19393.1 - 0.0028 17.6 0.2 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 EDO19393.1 - 0.0039 17.3 0.0 0.014 15.5 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 EDO19393.1 - 0.0056 16.1 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EDO19393.1 - 0.0068 16.3 0.1 0.019 14.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EDO19393.1 - 0.0075 16.5 4.6 0.0078 16.5 0.0 2.8 2 0 0 2 2 2 1 ABC transporter NTPase_1 PF03266.10 EDO19393.1 - 0.0099 15.5 0.3 0.021 14.5 0.2 1.5 1 0 0 1 1 1 1 NTPase cobW PF02492.14 EDO19393.1 - 0.012 15.1 0.2 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EDO19393.1 - 0.017 15.4 0.0 0.017 15.4 0.0 4.3 4 2 0 4 4 3 0 AAA domain AAA_11 PF13086.1 EDO19393.1 - 0.018 14.5 0.0 0.018 14.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EDO19393.1 - 0.023 14.4 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EDO19393.1 - 0.025 14.0 0.0 0.47 9.9 0.0 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation WAC_Acf1_DNA_bd PF10537.4 EDO19394.1 - 3.1e-36 123.6 2.9 5.4e-36 122.8 0.7 2.5 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EDO19394.1 - 9.8e-19 66.8 0.3 3.6e-18 65.0 0.1 2.1 2 0 0 2 2 2 1 DDT domain WHIM2 PF15613.1 EDO19394.1 - 2.3e-08 33.6 0.2 5.9e-08 32.3 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EDO19394.1 - 0.0021 17.9 1.8 0.0042 16.9 0.1 2.4 2 1 1 3 3 3 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ubiq_cyt_C_chap PF03981.7 EDO19395.1 - 1.6e-39 134.9 0.1 2.7e-39 134.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HK PF02110.10 EDO19396.1 - 2.9e-82 275.5 0.2 4.7e-82 274.8 0.1 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EDO19396.1 - 5.9e-55 185.1 0.0 9.4e-55 184.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 EDO19396.1 - 0.21 10.7 1.1 4 6.5 0.0 2.3 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase LRR_9 PF14580.1 EDO19397.1 - 1.2e-15 57.4 0.5 1.8e-15 56.9 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EDO19397.1 - 1.9e-07 30.5 7.5 0.00093 18.7 0.2 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EDO19397.1 - 0.00026 20.6 5.8 0.031 14.0 1.3 3.3 2 1 1 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 EDO19397.1 - 0.074 13.1 9.6 3.3 8.0 0.4 4.7 3 1 2 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 EDO19397.1 - 0.082 12.9 10.8 1.9 8.8 0.6 4.3 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 EDO19397.1 - 0.58 10.5 10.0 1.2 9.6 0.2 4.6 5 0 0 5 5 5 0 Leucine rich repeat zf-HC5HC2H_2 PF13832.1 EDO19398.1 - 4.2e-15 55.7 2.4 4.2e-15 55.7 1.7 4.6 5 0 0 5 5 5 3 PHD-zinc-finger like domain BAH PF01426.13 EDO19398.1 - 5.5e-12 45.4 0.1 5.5e-12 45.4 0.1 3.0 3 0 0 3 3 3 1 BAH domain PHD PF00628.24 EDO19398.1 - 6.8e-11 41.6 52.7 3e-07 30.0 2.7 5.1 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 EDO19398.1 - 5.5e-08 31.9 1.6 5.5e-08 31.9 1.1 5.2 5 0 0 5 5 5 2 PHD-finger C1_1 PF00130.17 EDO19398.1 - 0.035 13.8 43.3 0.014 15.0 2.6 6.2 6 0 0 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DEAD PF00270.24 EDO19399.1 - 1e-31 109.6 0.0 2.1e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO19399.1 - 1.5e-13 50.3 0.0 3.9e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EDO19399.1 - 3.9e-09 35.7 0.0 8.7e-09 34.5 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EDO19399.1 - 5.6e-07 29.5 0.1 1.2e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF87 PF01935.12 EDO19399.1 - 0.01 15.6 3.5 1 9.1 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function DUF87 AAA_22 PF13401.1 EDO19399.1 - 0.041 14.0 0.7 0.73 9.9 0.5 2.6 1 1 0 1 1 1 0 AAA domain SET PF00856.23 EDO19400.1 - 0.00037 20.8 0.1 0.00089 19.5 0.1 1.7 1 0 0 1 1 1 1 SET domain Radical_SAM PF04055.16 EDO19401.1 - 3.6e-23 82.5 0.0 7.7e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EDO19401.1 - 1.9e-20 72.7 0.0 6.9e-20 70.9 0.0 2.1 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EDO19401.1 - 1.8e-15 57.2 0.0 7.1e-15 55.2 0.0 2.1 1 1 0 1 1 1 1 Flavodoxin Glycos_transf_1 PF00534.15 EDO19402.1 - 1.5e-36 125.4 0.1 2e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EDO19402.1 - 2.4e-07 30.6 0.0 9.9e-07 28.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EDO19402.1 - 3.3e-06 27.2 0.0 6.5e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 SCA7 PF08313.7 EDO19403.1 - 3.9e-34 116.0 1.1 3.9e-34 116.0 0.7 2.6 2 0 0 2 2 2 1 SCA7, zinc-binding domain GDPD PF03009.12 EDO19404.1 - 3.7e-35 121.6 0.5 1.5e-34 119.6 0.4 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3132 PF11330.3 EDO19404.1 - 0.043 13.6 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) NUDIX PF00293.23 EDO19405.1 - 3.7e-11 42.7 0.0 6.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 EDO19405.1 - 1e-05 24.8 0.3 2.6e-05 23.6 0.2 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.6 EDO19405.1 - 0.0001 22.6 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Zn_ribbon_recom PF13408.1 EDO19405.1 - 0.07 13.4 0.7 0.35 11.1 0.5 2.2 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF4220 PF13968.1 EDO19405.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) zf-TFIIB PF13453.1 EDO19405.1 - 0.1 11.7 0.8 8.7 5.6 0.0 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger Pkinase PF00069.20 EDO19406.1 - 9.6e-41 139.6 0.0 1.5e-40 138.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO19406.1 - 5.5e-14 51.8 0.0 8.3e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EDO19406.1 - 0.059 13.0 0.0 0.71 9.5 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L12 PF00542.14 EDO19407.1 - 1.7e-19 69.5 6.4 1.7e-19 69.5 4.4 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 EDO19407.1 - 2.4 8.6 25.0 4 7.9 12.6 3.1 1 1 0 2 2 2 0 60s Acidic ribosomal protein KxDL PF10241.4 EDO19408.1 - 3.5e-09 36.4 2.0 5.1e-09 35.9 1.4 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF2968 PF11180.3 EDO19408.1 - 0.1 11.9 0.2 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Adaptin_N PF01602.15 EDO19409.1 - 5.1e-114 381.4 13.1 6.3e-114 381.1 9.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EDO19409.1 - 7.8e-07 29.2 0.0 0.033 14.4 0.0 4.4 2 2 3 5 5 5 3 HEAT repeats Cnd1 PF12717.2 EDO19409.1 - 1.2e-06 28.5 1.0 1.2e-06 28.5 0.7 3.1 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EDO19409.1 - 0.0042 17.4 2.3 0.092 13.1 0.2 3.6 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EDO19409.1 - 0.011 15.7 1.1 65 4.0 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat Yae1_N PF09811.4 EDO19409.1 - 0.044 13.3 0.2 0.086 12.3 0.1 1.5 1 0 0 1 1 1 0 Essential protein Yae1, N terminal HEAT_EZ PF13513.1 EDO19409.1 - 0.073 13.5 0.9 12 6.5 0.0 4.5 5 2 2 7 7 7 0 HEAT-like repeat Rad9 PF04139.8 EDO19410.1 - 9.1e-09 34.7 5.1 7.4e-07 28.5 3.6 2.4 1 1 0 1 1 1 1 Rad9 PCNA_N PF00705.13 EDO19410.1 - 0.017 14.6 0.1 0.066 12.7 0.0 2.0 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, N-terminal domain NUFIP1 PF10453.4 EDO19411.1 - 6.1e-18 64.0 0.5 6.1e-18 64.0 0.3 2.7 3 0 0 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF544 PF04424.8 EDO19412.1 - 1.6e-30 105.3 0.1 3.4e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Transglut_i_TM PF14400.1 EDO19412.1 - 0.00015 21.3 1.2 0.00027 20.4 0.8 1.4 1 0 0 1 1 1 1 Inactive transglutaminase fused to 7 transmembrane helices Molybdopterin PF00384.17 EDO19413.1 - 0.02 13.6 0.1 0.03 13.0 0.1 1.2 1 0 0 1 1 1 0 Molybdopterin oxidoreductase Ibs_toxin PF13956.1 EDO19413.1 - 0.26 11.1 1.7 0.53 10.1 1.2 1.4 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Pkinase PF00069.20 EDO19414.1 - 6.5e-21 74.6 0.1 1.3e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO19414.1 - 3.9e-14 52.3 0.0 6.9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4591 PF15261.1 EDO19414.1 - 4.3 7.5 5.8 15 5.8 4.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4591) MBOAT PF03062.14 EDO19415.1 - 9.3e-55 185.9 25.4 9.3e-55 185.9 17.6 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family SNase PF00565.12 EDO19416.1 - 4.1e-25 88.1 0.0 6.4e-25 87.5 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MAD PF05557.8 EDO19417.1 - 6.4e-24 84.0 88.4 3.1e-23 81.8 61.2 1.8 1 1 0 1 1 1 1 Mitotic checkpoint protein CRISPR_Cas2 PF09827.4 EDO19417.1 - 2.2 8.4 8.7 0.31 11.1 0.1 4.0 3 1 0 3 3 3 0 CRISPR associated protein Cas2 UQ_con PF00179.21 EDO19418.1 - 1.7e-16 59.8 0.1 2e-16 59.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EDO19418.1 - 0.00089 19.1 0.0 0.00093 19.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain NAD_kinase PF01513.16 EDO19419.1 - 4.4e-53 179.9 0.1 5.6e-53 179.5 0.1 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EDO19419.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Glyco_hydro_10 PF00331.15 EDO19419.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 MF_alpha PF04648.7 EDO19420.1 - 2.3e-28 96.6 24.9 7.9e-05 22.6 0.3 5.3 5 0 0 5 5 5 5 Yeast mating factor alpha hormone MF_alpha_N PF05436.6 EDO19420.1 - 9e-26 89.3 2.6 1.3e-25 88.8 1.8 1.2 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus DUF1659 PF07872.6 EDO19420.1 - 0.00094 18.7 0.2 44 3.8 0.0 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1659) Vac_ImportDeg PF09783.4 EDO19420.1 - 1.9 7.9 7.5 9.6 5.6 0.2 2.8 1 1 1 2 2 2 0 Vacuolar import and degradation protein DUF4592 PF15262.1 EDO19421.1 - 0.0051 17.3 1.0 1.6 9.2 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4592) RRM_6 PF14259.1 EDO19422.1 - 7.9e-28 96.2 0.5 1.1e-05 25.3 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EDO19422.1 - 4.3e-25 87.1 0.9 1.2e-08 34.4 0.1 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO19422.1 - 4.1e-21 74.5 1.8 6.3e-07 29.1 0.1 5.0 4 1 1 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO19422.1 - 0.13 12.0 0.0 0.79 9.5 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EDO19422.1 - 0.14 11.9 0.3 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif XLF PF09302.6 EDO19423.1 - 5.5e-33 114.1 3.2 1e-32 113.2 2.2 1.4 1 0 0 1 1 1 1 XLF (XRCC4-like factor) ParA PF10609.4 EDO19424.1 - 2.9e-36 123.1 0.0 7.8e-36 121.8 0.0 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EDO19424.1 - 4.3e-15 55.6 0.0 6.2e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EDO19424.1 - 3.5e-05 23.0 0.0 5.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 EDO19424.1 - 0.00012 22.0 0.0 0.00048 20.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EDO19424.1 - 0.00012 21.2 0.2 0.0062 15.6 0.0 2.7 2 1 0 2 2 2 1 Anion-transporting ATPase DUF258 PF03193.11 EDO19424.1 - 0.0041 16.3 0.0 0.0078 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 TF_Zn_Ribbon PF08271.7 EDO19424.1 - 0.032 13.5 0.6 0.079 12.2 0.4 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding AAA_25 PF13481.1 EDO19424.1 - 0.034 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EDO19424.1 - 0.19 10.5 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Spc7 PF08317.6 EDO19425.1 - 7.6e-97 323.8 24.8 7.6e-97 323.8 17.2 2.6 1 1 2 3 3 3 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EDO19425.1 - 2e-15 56.1 0.9 6.8e-15 54.4 0.6 2.0 1 0 0 1 1 1 1 Spc7_C2 Tup_N PF08581.5 EDO19425.1 - 0.073 13.2 9.5 0.048 13.8 3.0 3.3 1 1 1 2 2 2 0 Tup N-terminal Ribosomal_L36 PF00444.13 EDO19426.1 - 5.9e-20 70.9 10.0 8.3e-20 70.4 6.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 EDO19426.1 - 0.0064 15.7 1.5 0.01 15.1 1.1 1.3 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family Mgm101p PF06420.7 EDO19426.1 - 0.049 12.9 0.1 0.052 12.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 WD40 PF00400.27 EDO19427.1 - 4e-24 83.5 22.0 1.4e-08 34.2 0.2 9.5 11 0 0 11 11 11 5 WD domain, G-beta repeat Nup160 PF11715.3 EDO19427.1 - 7.6e-05 21.0 3.7 0.081 11.0 0.1 3.5 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EDO19427.1 - 0.0014 17.4 7.4 0.0014 17.4 0.4 3.7 3 1 0 4 4 4 1 Nup133 N terminal like YmzC PF14157.1 EDO19427.1 - 0.046 13.5 0.0 3.6 7.4 0.0 2.7 2 0 0 2 2 2 0 YmzC-like protein DUF2222 PF09984.4 EDO19427.1 - 0.12 11.7 0.2 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) DUF4388 PF14332.1 EDO19427.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) TCO89 PF10452.4 EDO19428.1 - 3.3e-237 789.2 58.3 3.3e-237 789.2 40.4 1.3 2 0 0 2 2 2 1 TORC1 subunit TCO89 Sec1 PF00995.18 EDO19429.1 - 1.4e-139 466.3 17.1 1.6e-139 466.1 11.9 1.0 1 0 0 1 1 1 1 Sec1 family PHD PF00628.24 EDO19430.1 - 1.5e-11 43.7 7.1 2.7e-11 42.9 4.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EDO19430.1 - 0.42 9.9 6.0 0.73 9.2 4.2 1.4 1 0 0 1 1 1 0 PHD-finger Meleagrin PF08189.6 EDO19431.1 - 0.26 10.7 1.3 0.45 10.0 0.4 1.7 2 0 0 2 2 2 0 Meleagrin/Cygnin family RRM_1 PF00076.17 EDO19432.1 - 2e-15 56.1 0.0 3.1e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO19432.1 - 5.5e-13 48.6 0.0 8.9e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO19432.1 - 1.5e-09 37.5 0.0 2.8e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAHP_synth_1 PF00793.15 EDO19433.1 - 9.7e-104 345.8 0.0 1.2e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family RCC1 PF00415.13 EDO19434.1 - 8e-61 202.0 0.1 7e-10 38.9 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EDO19434.1 - 3.2e-37 125.3 16.9 6.9e-09 35.0 0.0 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat MMR_HSR1 PF01926.18 EDO19435.1 - 4.2e-17 62.1 0.3 1.5e-14 53.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EDO19435.1 - 1.5e-07 30.8 0.4 1.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EDO19435.1 - 0.00061 19.0 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EDO19435.1 - 0.00087 19.1 2.6 0.026 14.3 0.6 3.1 2 1 0 2 2 2 1 Dynamin family AIG1 PF04548.11 EDO19435.1 - 0.0033 16.5 0.1 0.0075 15.3 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EDO19435.1 - 0.014 15.8 0.9 0.093 13.2 0.1 2.4 2 0 0 2 2 2 0 Miro-like protein WD40 PF00400.27 EDO19436.1 - 0.079 12.8 8.0 21 5.2 0.2 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat SNF2_N PF00176.18 EDO19437.1 - 3.1e-78 262.6 0.3 6.1e-78 261.6 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EDO19437.1 - 1.1e-41 141.3 1.2 1.1e-41 141.3 0.8 4.2 5 0 0 5 5 5 1 SLIDE HAND PF09110.6 EDO19437.1 - 4.3e-33 114.0 1.7 4.3e-33 114.0 1.2 4.3 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 EDO19437.1 - 1.6e-15 56.6 0.0 5.9e-15 54.8 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EDO19437.1 - 6.9e-07 29.2 0.0 6.9e-07 29.2 0.0 4.4 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EDO19437.1 - 8.7e-05 22.0 0.0 0.00023 20.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EDO19437.1 - 0.013 15.3 0.1 0.083 12.7 0.1 2.4 1 0 0 1 1 1 0 AAA domain GSHPx PF00255.14 EDO19438.1 - 1.2e-47 159.7 0.1 1.6e-47 159.3 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EDO19438.1 - 3.5e-05 23.4 0.0 0.00022 20.9 0.0 2.0 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EDO19438.1 - 0.00067 19.2 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 Redoxin HD_3 PF13023.1 EDO19439.1 - 6.5e-36 123.5 0.2 8.7e-36 123.1 0.2 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.17 EDO19439.1 - 6.7e-07 29.3 0.1 1.1e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 EDO19439.1 - 0.0065 16.2 0.2 0.0086 15.8 0.1 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Ribosomal_L18e PF00828.14 EDO19440.1 - 5.8e-35 120.4 0.3 8.1e-35 120.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RTC4 PF14474.1 EDO19440.1 - 0.15 11.9 0.1 0.75 9.7 0.0 1.9 1 1 0 2 2 2 0 RTC4-like domain tRNA_bind PF01588.15 EDO19441.1 - 9.6e-29 99.0 0.0 1.7e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Viral_protease PF08715.5 EDO19441.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Papain like viral protease Tom37_C PF11801.3 EDO19441.1 - 0.22 11.3 3.7 0.47 10.2 2.6 1.6 1 0 0 1 1 1 0 Tom37 C-terminal domain Suf PF05843.9 EDO19441.1 - 0.33 10.6 7.5 0.58 9.8 5.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EF-hand_7 PF13499.1 EDO19442.1 - 4.1e-11 42.8 0.4 6.1e-09 35.8 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EDO19442.1 - 1.5e-09 37.6 0.0 0.0015 18.3 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EDO19442.1 - 1.3e-08 34.3 0.8 7.9e-07 28.6 0.1 3.1 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.27 EDO19442.1 - 8.9e-08 30.9 8.0 0.0001 21.3 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EDO19442.1 - 3.5e-07 29.5 4.3 0.00035 20.2 0.1 3.7 3 1 1 4 4 4 2 EF-hand domain UPF0154 PF03672.8 EDO19442.1 - 0.0026 17.3 0.0 0.069 12.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 EDO19442.1 - 0.18 11.2 0.0 0.18 11.2 0.0 3.2 3 0 0 3 3 3 0 EF hand Cytochrom_C PF00034.16 EDO19444.1 - 0.29 11.9 2.4 0.29 12.0 0.3 1.8 2 0 0 2 2 2 0 Cytochrome c Vfa1 PF08432.5 EDO19444.1 - 5.7 6.9 19.6 6.8 6.6 13.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CUE PF02845.11 EDO19445.1 - 1.9e-07 30.4 0.6 4.7e-07 29.1 0.4 1.8 1 0 0 1 1 1 1 CUE domain Miro PF08477.8 EDO19445.1 - 0.088 13.3 2.6 0.36 11.3 1.8 2.1 1 0 0 1 1 1 0 Miro-like protein WD40 PF00400.27 EDO19446.1 - 3.7e-16 58.3 15.1 1e-05 25.2 0.0 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 EDO19446.1 - 0.0023 17.6 0.1 0.09 12.4 0.0 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Rax2 PF12768.2 EDO19446.1 - 0.0062 15.7 0.2 0.0062 15.7 0.2 2.0 2 1 0 2 2 2 1 Cortical protein marker for cell polarity Hira PF07569.6 EDO19446.1 - 0.029 13.5 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split DASH_Dad3 PF08656.5 EDO19447.1 - 2e-29 101.0 2.1 2.2e-29 100.9 1.5 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 DUF1546 PF07571.8 EDO19448.1 - 1.1e-30 105.6 0.0 2.1e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EDO19448.1 - 3.6e-28 97.3 0.2 7.6e-28 96.2 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EDO19448.1 - 0.00063 19.8 0.0 0.0036 17.3 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.9 EDO19448.1 - 0.009 15.3 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CENP-S PF15630.1 EDO19448.1 - 0.016 15.3 0.8 2.6 8.2 0.0 2.8 3 0 0 3 3 3 0 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EDO19448.1 - 0.025 14.6 0.2 0.081 12.9 0.0 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.10 EDO19448.1 - 0.057 13.2 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit SLD3 PF08639.5 EDO19449.1 - 5.3e-100 335.4 35.1 1.3e-99 334.1 24.3 1.6 1 1 0 1 1 1 1 DNA replication regulator SLD3 BCNT PF07572.7 EDO19450.1 - 1e-27 95.8 0.6 3.9e-27 94.0 0.2 2.2 2 0 0 2 2 2 1 Bucentaur or craniofacial development OPT PF03169.10 EDO19451.1 - 2.5e-154 515.1 22.4 2.8e-154 514.9 15.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CBS PF00571.23 EDO19452.1 - 2.4e-30 104.0 2.6 1.4e-11 43.9 0.0 4.3 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.6 EDO19452.1 - 0.11 12.3 0.9 2.1 8.3 0.1 3.1 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain WD40 PF00400.27 EDO19453.1 - 3.7e-21 74.1 17.4 5.6e-07 29.2 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat DUF4340 PF14238.1 EDO19454.1 - 0.013 15.1 1.2 0.02 14.5 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4340) Aminotran_1_2 PF00155.16 EDO19455.1 - 2.7e-68 230.5 0.0 3.2e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EDO19455.1 - 0.0019 16.9 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V ABC_tran PF00005.22 EDO19456.1 - 4.2e-26 91.8 0.1 1.7e-15 57.5 0.0 3.0 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EDO19456.1 - 1e-07 32.2 10.1 0.0014 18.6 2.8 3.6 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EDO19456.1 - 1.6e-05 24.7 0.0 0.0064 16.3 0.0 2.7 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EDO19456.1 - 0.0021 17.5 0.1 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EDO19456.1 - 0.0022 18.1 0.3 1 9.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EDO19456.1 - 0.037 14.3 4.0 0.042 14.1 0.1 2.5 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.14 EDO19456.1 - 0.094 11.9 0.1 0.24 10.5 0.1 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain GDI PF00996.13 EDO19457.1 - 1.7e-211 702.2 0.2 2e-211 701.9 0.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EDO19457.1 - 0.036 14.0 0.1 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-CCHC PF00098.18 EDO19458.1 - 0.026 14.4 0.9 0.037 13.9 0.6 1.2 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 EDO19458.1 - 0.11 12.2 2.0 0.29 10.8 1.4 1.8 1 1 0 1 1 1 0 Zinc knuckle DUF4342 PF14242.1 EDO19458.1 - 4 7.2 6.3 0.57 9.9 1.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) UAF_Rrn10 PF05234.6 EDO19459.1 - 1.7e-45 153.9 0.1 2e-45 153.6 0.1 1.1 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Nol1_Nop2_Fmu PF01189.12 EDO19460.1 - 8.7e-93 310.7 0.0 9.7e-76 254.8 0.0 2.2 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 EDO19460.1 - 8.1e-05 22.6 0.4 0.00033 20.6 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EDO19460.1 - 0.0014 19.2 0.0 0.0041 17.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO19460.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EDO19460.1 - 0.03 13.3 0.0 0.053 12.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CBFD_NFYB_HMF PF00808.18 EDO19461.1 - 1.4e-24 85.8 0.0 2.2e-24 85.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EDO19461.1 - 1.2e-05 25.2 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 EDO19461.1 - 0.024 14.9 0.2 0.16 12.2 0.0 2.3 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A PAN_3 PF08277.7 EDO19461.1 - 0.045 13.3 0.2 0.077 12.6 0.2 1.4 1 0 0 1 1 1 0 PAN-like domain Bromo_TP PF07524.8 EDO19461.1 - 0.069 12.8 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Bromodomain associated Pkinase PF00069.20 EDO19462.1 - 3.3e-73 246.0 0.0 3.9e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO19462.1 - 2.1e-32 112.1 0.0 2.8e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO19462.1 - 9.1e-05 21.5 0.0 0.00026 20.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EDO19462.1 - 0.0013 18.1 0.1 0.002 17.5 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EDO19462.1 - 0.047 12.7 0.1 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family P22_AR_C PF10548.4 EDO19462.1 - 0.062 13.1 0.1 5.5 6.9 0.0 2.5 2 0 0 2 2 2 0 P22AR C-terminal domain APH PF01636.18 EDO19462.1 - 0.062 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family AcetylCoA_hydro PF02550.10 EDO19463.1 - 2.5e-66 223.2 0.0 5.1e-66 222.2 0.0 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EDO19463.1 - 2.8e-40 137.5 0.0 4.1e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.7 EDO19463.1 - 0.0031 16.2 0.3 0.006 15.3 0.2 1.4 1 1 0 1 1 1 1 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.18 EDO19463.1 - 0.017 14.2 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Coenzyme A transferase DNA_topoisoIV PF00521.15 EDO19464.1 - 1.8e-118 396.1 0.1 1.8e-118 396.1 0.1 2.4 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EDO19464.1 - 1.8e-35 121.7 7.0 4.3e-35 120.4 4.9 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EDO19464.1 - 3.1e-12 46.3 0.0 1.2e-11 44.4 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EDO19464.1 - 1e-09 38.0 0.0 2.7e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OST3_OST6 PF04756.8 EDO19465.1 - 6.7e-20 71.2 6.5 1.3e-19 70.3 4.5 1.4 1 0 0 1 1 1 1 OST3 / OST6 family YbjM PF11045.3 EDO19465.1 - 0.11 12.2 2.1 0.47 10.2 0.0 2.3 1 1 1 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae MKT1_N PF12247.3 EDO19466.1 - 6.2e-22 77.7 0.2 2.7e-21 75.6 0.0 2.2 3 0 0 3 3 3 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 EDO19466.1 - 1.7e-21 76.3 0.0 3.1e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EDO19466.1 - 2.6e-09 37.0 0.0 5.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region MKT1_C PF12246.3 EDO19467.1 - 5.7e-69 231.8 6.4 7.1e-69 231.4 4.4 1.1 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication EF-hand_4 PF12763.2 EDO19468.1 - 3.7e-51 171.2 8.6 3.6e-49 164.8 1.9 2.9 3 1 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 EDO19468.1 - 1.3e-33 116.2 11.9 5.6e-32 110.9 8.2 2.3 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.27 EDO19468.1 - 0.023 13.9 1.9 0.067 12.5 1.3 1.9 1 0 0 1 1 1 0 EF hand FlaC_arch PF05377.6 EDO19468.1 - 0.062 13.2 4.4 4.1 7.3 0.7 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) EF-hand_8 PF13833.1 EDO19468.1 - 0.11 12.1 1.0 0.24 11.0 0.7 1.6 1 0 0 1 1 1 0 EF-hand domain pair Sugarporin_N PF11471.3 EDO19468.1 - 0.41 10.3 8.0 1 9.0 2.0 2.6 2 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension IncA PF04156.9 EDO19468.1 - 0.69 9.4 9.9 1.2 8.7 6.9 1.4 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EDO19468.1 - 2.3 8.7 5.7 3.8 8.0 0.4 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Bap31 PF05529.7 EDO19468.1 - 2.9 7.3 6.8 8.7 5.7 2.6 2.3 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Ribosomal_S13 PF00416.17 EDO19469.1 - 5.3e-22 78.2 0.1 6e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Tropomyosin_1 PF12718.2 EDO19470.1 - 1.8e-47 160.7 43.4 2.2e-47 160.5 30.1 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EDO19470.1 - 1.4e-08 34.1 37.8 0.00026 20.1 9.7 2.1 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 EDO19470.1 - 4e-07 29.9 41.5 1.5e-06 28.1 5.6 2.5 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KLRAQ PF10205.4 EDO19470.1 - 0.00017 21.5 13.8 0.00017 21.5 9.6 2.2 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Laminin_II PF06009.7 EDO19470.1 - 0.00019 21.1 24.9 0.002 17.8 8.0 2.5 1 1 1 2 2 2 2 Laminin Domain II ADIP PF11559.3 EDO19470.1 - 0.0016 18.3 35.5 0.16 11.9 9.6 2.2 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding GAS PF13851.1 EDO19470.1 - 0.0016 17.6 39.4 0.18 10.9 9.9 2.4 1 1 0 2 2 2 2 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 EDO19470.1 - 0.0017 18.1 44.8 0.0051 16.5 12.9 3.4 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 EDO19470.1 - 0.0047 16.7 36.0 0.01 15.6 9.6 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF3287 PF11690.3 EDO19470.1 - 0.0085 16.1 4.2 0.0085 16.1 2.9 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3287) FlaC_arch PF05377.6 EDO19470.1 - 0.0099 15.7 27.3 0.29 11.0 0.3 4.8 2 2 2 4 4 4 2 Flagella accessory protein C (FlaC) MbeD_MobD PF04899.7 EDO19470.1 - 0.013 15.3 11.2 0.021 14.6 1.4 2.8 2 1 1 3 3 3 0 MbeD/MobD like BLOC1_2 PF10046.4 EDO19470.1 - 0.016 15.3 31.0 0.11 12.6 7.9 3.8 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myosin_tail_1 PF01576.14 EDO19470.1 - 0.017 12.8 37.0 0.12 10.0 25.6 1.8 1 1 0 1 1 1 0 Myosin tail DivIC PF04977.10 EDO19470.1 - 0.023 14.1 9.9 0.023 14.1 6.9 4.2 1 1 3 4 4 4 0 Septum formation initiator Reo_sigmaC PF04582.7 EDO19470.1 - 0.031 13.4 8.8 0.41 9.7 1.8 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein LPP PF04728.8 EDO19470.1 - 0.034 13.9 1.9 0.33 10.7 0.6 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper APG6 PF04111.7 EDO19470.1 - 0.038 13.0 41.5 0.51 9.3 18.2 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 IFT57 PF10498.4 EDO19470.1 - 0.069 11.8 31.1 0.43 9.2 16.5 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 IncA PF04156.9 EDO19470.1 - 0.079 12.5 39.0 11 5.5 27.0 2.1 1 1 0 1 1 1 0 IncA protein Filament PF00038.16 EDO19470.1 - 0.097 12.1 31.6 0.54 9.6 9.2 2.0 1 1 1 2 2 2 0 Intermediate filament protein Sec2p PF06428.6 EDO19470.1 - 0.13 12.0 34.6 0.079 12.8 13.6 3.3 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DUF3450 PF11932.3 EDO19470.1 - 0.21 10.8 27.8 0.6 9.3 12.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Ax_dynein_light PF10211.4 EDO19470.1 - 0.22 11.3 36.4 0.46 10.2 11.8 3.1 1 1 1 3 3 3 0 Axonemal dynein light chain HA PF03457.9 EDO19470.1 - 0.23 11.5 2.6 4.3 7.5 0.2 2.7 2 0 0 2 2 2 0 Helicase associated domain Atg14 PF10186.4 EDO19470.1 - 0.25 10.2 29.6 0.98 8.3 17.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Imm15 PF15590.1 EDO19470.1 - 0.28 10.3 5.1 2.1 7.4 0.2 2.7 2 1 0 2 2 2 0 Immunity protein 15 ERM PF00769.14 EDO19470.1 - 0.43 10.0 38.1 0.35 10.3 15.4 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Laminin_I PF06008.9 EDO19470.1 - 0.47 9.7 28.7 1.5 8.0 18.8 2.0 1 1 0 1 1 1 0 Laminin Domain I Mod_r PF07200.8 EDO19470.1 - 0.51 10.2 33.4 0.84 9.5 9.0 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein AAA_13 PF13166.1 EDO19470.1 - 0.52 8.7 33.1 0.13 10.7 8.8 2.0 1 1 0 1 1 1 0 AAA domain bZIP_1 PF00170.16 EDO19470.1 - 0.59 10.1 40.0 0.53 10.2 1.2 4.4 1 1 3 4 4 4 0 bZIP transcription factor DUF3584 PF12128.3 EDO19470.1 - 0.6 7.3 31.6 0.68 7.1 21.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) WXG100 PF06013.7 EDO19470.1 - 0.63 10.0 13.6 4.4 7.3 2.5 3.7 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF4201 PF13870.1 EDO19470.1 - 0.68 9.3 37.0 1.4 8.3 17.5 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) GOLGA2L5 PF15070.1 EDO19470.1 - 0.72 8.2 27.3 0.94 7.8 18.9 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Phage_GP20 PF06810.6 EDO19470.1 - 0.73 9.2 39.7 0.13 11.7 11.2 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF904 PF06005.7 EDO19470.1 - 0.74 10.1 48.0 7.6 6.9 13.6 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF904) NPV_P10 PF05531.7 EDO19470.1 - 0.77 10.0 16.8 4 7.7 0.2 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 EDO19470.1 - 0.78 9.3 20.9 1 8.9 10.9 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF972 PF06156.8 EDO19470.1 - 0.94 9.8 31.6 0.14 12.5 8.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) EzrA PF06160.7 EDO19470.1 - 1 7.4 31.3 0.99 7.5 8.2 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA FTO_CTD PF12934.2 EDO19470.1 - 1.1 8.8 13.0 0.11 12.0 3.1 2.2 1 1 1 2 2 2 0 FTO C-terminal domain Rootletin PF15035.1 EDO19470.1 - 1.1 9.1 36.1 2.3 8.1 12.3 2.7 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Lebercilin PF15619.1 EDO19470.1 - 1.2 8.5 34.9 5.4 6.3 20.5 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Mnd1 PF03962.10 EDO19470.1 - 1.4 8.5 35.1 1 8.9 11.6 2.2 1 1 1 2 2 2 0 Mnd1 family Spc7 PF08317.6 EDO19470.1 - 1.5 7.3 35.5 0.34 9.5 9.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.7 EDO19470.1 - 1.5 8.5 18.9 2.1 8.1 4.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.6 EDO19470.1 - 1.6 8.4 39.0 1.8 8.3 3.4 4.0 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.5 EDO19470.1 - 1.7 8.7 24.7 2 8.5 10.3 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Hemerythrin PF01814.18 EDO19470.1 - 1.8 8.7 8.0 4.7 7.3 0.3 2.5 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Hormone_1 PF00103.15 EDO19470.1 - 1.8 7.8 14.3 0.64 9.3 6.0 2.1 1 1 1 2 2 2 0 Somatotropin hormone family Fzo_mitofusin PF04799.8 EDO19470.1 - 1.9 7.8 21.2 1.4 8.3 4.0 2.6 1 1 1 2 2 2 0 fzo-like conserved region HOOK PF05622.7 EDO19470.1 - 2 6.1 32.4 2.3 5.9 22.4 1.1 1 0 0 1 1 1 0 HOOK protein OmpH PF03938.9 EDO19470.1 - 2 8.3 33.7 0.09 12.7 8.7 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CCDC155 PF14662.1 EDO19470.1 - 2.1 7.8 38.1 0.13 11.8 11.1 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF724 PF05266.9 EDO19470.1 - 2.4 7.7 30.6 2 7.9 14.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF869 PF05911.6 EDO19470.1 - 2.8 6.0 32.9 3.3 5.8 22.2 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Vps5 PF09325.5 EDO19470.1 - 2.9 7.0 26.3 2.3 7.4 1.9 3.7 1 1 3 4 4 4 0 Vps5 C terminal like Lectin_N PF03954.9 EDO19470.1 - 3.3 7.0 15.1 6.4 6.1 5.1 2.5 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Prefoldin_2 PF01920.15 EDO19470.1 - 3.4 7.4 43.8 2.4 7.9 4.9 4.4 1 1 2 3 3 3 0 Prefoldin subunit Striatin PF08232.7 EDO19470.1 - 3.6 7.8 26.8 10 6.4 13.7 2.2 1 1 1 2 2 2 0 Striatin family TPR_MLP1_2 PF07926.7 EDO19470.1 - 3.8 7.2 40.9 1.3e+03 -1.0 27.9 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TBPIP PF07106.8 EDO19470.1 - 3.9 6.9 36.7 5.9 6.3 12.3 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) YlqD PF11068.3 EDO19470.1 - 4 7.4 26.0 3.6 7.6 5.2 2.3 1 1 1 2 2 2 0 YlqD protein NDUFB10 PF10249.4 EDO19470.1 - 4.2 7.5 7.5 24 5.1 0.1 2.8 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase subunit 10 CENP-K PF11802.3 EDO19470.1 - 5 6.2 27.6 0.1 11.8 6.1 2.1 1 1 1 2 2 2 0 Centromere-associated protein K Kinetocho_Slk19 PF12709.2 EDO19470.1 - 6.3 6.9 37.2 3.9 7.6 2.3 3.8 1 1 3 4 4 4 0 Central kinetochore-associated bZIP_2 PF07716.10 EDO19470.1 - 6.3 6.6 37.6 0.086 12.6 2.0 4.7 2 2 2 4 4 3 0 Basic region leucine zipper DUF4200 PF13863.1 EDO19470.1 - 6.7 6.6 41.3 4.1 7.3 17.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) G6PD_N PF00479.17 EDO19470.1 - 6.9 6.8 10.5 0.18 11.9 1.2 2.1 1 1 1 2 2 2 0 Glucose-6-phosphate dehydrogenase, NAD binding domain DivIVA PF05103.8 EDO19470.1 - 7.2 6.6 32.9 13 5.8 7.0 3.6 1 1 2 3 3 3 0 DivIVA protein WEMBL PF05701.6 EDO19470.1 - 7.3 4.9 36.2 6.2 5.1 10.2 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF2959 PF11172.3 EDO19470.1 - 7.3 6.2 21.9 1.1 8.9 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Peptidase_M1 PF01433.15 EDO19471.1 - 4.3e-92 309.2 1.6 4.3e-92 309.2 1.1 2.2 3 0 0 3 3 3 1 Peptidase family M1 ERAP1_C PF11838.3 EDO19471.1 - 6.6e-49 166.9 0.0 9.8e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EDO19471.1 - 2e-16 60.1 0.0 4.2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DnaJ PF00226.26 EDO19472.1 - 1.5e-23 82.2 3.2 3e-23 81.2 2.2 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EDO19472.1 - 2.6e-14 52.8 1.3 8.5e-13 48.0 0.1 2.7 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EDO19472.1 - 7.7e-11 41.8 14.2 1.4e-10 41.0 9.9 1.5 1 0 0 1 1 1 1 DnaJ central domain UPF0223 PF05256.7 EDO19472.1 - 0.13 12.3 1.9 0.34 11.0 1.3 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0223) DUF1021 PF06257.6 EDO19473.1 - 0.2 11.3 0.6 3.2 7.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1021) Cytokin_check_N PF10407.4 EDO19474.1 - 1.7e-30 104.4 4.6 1.7e-30 104.4 3.2 2.0 2 0 0 2 2 2 1 Cdc14 phosphatase binding protein N-terminus SMC_N PF02463.14 EDO19475.1 - 1.9e-51 174.4 59.0 3.9e-50 170.1 40.9 3.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EDO19475.1 - 4.3e-30 104.1 0.0 2e-29 102.0 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EDO19475.1 - 5.1e-09 36.4 39.2 4.4e-05 23.5 0.0 5.4 3 2 0 3 3 2 2 AAA domain AAA_23 PF13476.1 EDO19475.1 - 3.1e-06 27.6 53.4 3.1e-06 27.6 37.0 7.6 3 2 2 5 5 2 1 AAA domain Myosin_tail_1 PF01576.14 EDO19475.1 - 0.00093 17.0 16.5 0.00093 17.0 11.4 4.0 2 2 1 3 3 3 2 Myosin tail CENP-F_leu_zip PF10473.4 EDO19475.1 - 0.0011 18.8 12.2 0.0011 18.8 8.5 7.9 4 2 3 8 8 8 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_29 PF13555.1 EDO19475.1 - 0.0011 18.4 0.0 0.0027 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.4 EDO19475.1 - 0.0029 17.7 6.8 0.0029 17.7 4.7 9.6 4 2 5 9 9 8 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 IFT46_B_C PF12317.3 EDO19475.1 - 0.0093 15.3 1.7 0.0093 15.3 1.2 4.4 4 1 0 5 5 5 1 Intraflagellar transport complex B protein 46 C terminal IncA PF04156.9 EDO19475.1 - 1.9 8.0 119.9 0.11 12.0 10.3 7.1 2 2 4 6 6 6 0 IncA protein Reo_sigmaC PF04582.7 EDO19475.1 - 5.9 5.9 47.2 0.01 15.0 1.6 5.8 4 2 2 6 6 6 0 Reovirus sigma C capsid protein FUSC PF04632.7 EDO19475.1 - 6.3 5.0 2.9 13 4.0 0.1 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family HrpB7 PF09486.5 EDO19475.1 - 9.7 6.0 28.0 1.5 8.7 0.5 6.1 4 3 2 6 6 6 0 Bacterial type III secretion protein (HrpB7) Mem_trans PF03547.13 EDO19476.1 - 1.5e-63 214.4 12.0 5.7e-63 212.5 8.4 1.7 1 1 0 1 1 1 1 Membrane transport protein TraG-D_C PF12696.2 EDO19476.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG DUF2542 PF10808.3 EDO19476.1 - 2.6 8.3 7.7 1 9.6 0.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2542) CcoS PF03597.10 EDO19476.1 - 3 7.3 6.4 3.9 7.0 0.4 3.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type WBS_methylT PF12589.3 EDO19477.1 - 1.8e-17 63.6 5.2 3.6e-17 62.6 3.6 1.6 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EDO19477.1 - 1.5e-14 54.2 0.0 8.1e-14 51.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EDO19477.1 - 3.4e-08 33.7 0.0 1.3e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EDO19477.1 - 4e-08 32.9 0.0 1.2e-07 31.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EDO19477.1 - 7.3e-07 29.5 0.0 3.7e-06 27.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EDO19477.1 - 7.4e-07 29.0 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EDO19477.1 - 1.1e-05 25.9 0.2 6.8e-05 23.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EDO19477.1 - 1.6e-05 24.9 0.0 0.00015 21.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EDO19477.1 - 0.0005 19.2 0.0 0.014 14.4 0.0 2.5 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase AdoMet_MTase PF07757.8 EDO19477.1 - 0.0036 17.4 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase PCMT PF01135.14 EDO19477.1 - 0.0042 16.6 0.0 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EDO19477.1 - 0.0051 16.1 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EDO19477.1 - 0.0079 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_N4_Mtase PF01555.13 EDO19477.1 - 0.052 13.0 0.3 0.45 9.9 0.0 2.1 2 1 0 2 2 2 0 DNA methylase Peptidase_S8 PF00082.17 EDO19478.1 - 4.1e-43 147.5 0.3 5.6e-43 147.0 0.2 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EDO19478.1 - 0.00095 19.6 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Imm28 PF15574.1 EDO19478.1 - 0.078 12.5 0.1 9.6 5.7 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 28 Tim17 PF02466.14 EDO19479.1 - 4e-27 94.7 2.4 5e-27 94.4 1.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ACC_central PF08326.7 EDO19481.1 - 1.1e-262 873.3 0.0 1.4e-262 872.9 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EDO19481.1 - 6.1e-181 602.0 0.0 8.3e-181 601.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EDO19481.1 - 1.6e-49 168.1 0.0 3.2e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EDO19481.1 - 7.4e-26 90.4 0.1 2e-25 89.0 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EDO19481.1 - 8.6e-21 73.9 0.0 4.4e-20 71.6 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EDO19481.1 - 3.3e-17 61.8 0.2 9.1e-17 60.4 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EDO19481.1 - 1.7e-10 40.9 0.0 5.8e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EDO19481.1 - 1.7e-08 33.5 0.0 0.00056 18.7 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EDO19481.1 - 0.0004 19.8 0.0 0.0012 18.2 0.0 1.8 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EDO19481.1 - 0.0065 16.3 0.0 0.032 14.0 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Atrophin-1 PF03154.10 EDO19481.1 - 2.5 6.1 0.8 3.6 5.6 0.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF2572 PF10833.3 EDO19482.1 - 0.026 13.9 0.1 0.031 13.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2572) DUF4611 PF15387.1 EDO19482.1 - 0.17 12.0 3.9 0.11 12.7 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EDO19482.1 - 7.6 6.0 6.6 12 5.4 4.6 1.4 1 1 0 1 1 1 0 Nucleoplasmin SPX PF03105.14 EDO19483.1 - 3.3e-49 168.1 9.4 3.3e-49 168.1 6.5 2.1 2 0 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 EDO19483.1 - 2.3e-26 92.7 44.2 3.4e-26 92.1 30.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EDO19483.1 - 5.7e-15 54.7 45.3 1.4e-11 43.5 17.5 2.2 1 1 1 2 2 2 2 Citrate transporter PFK PF00365.15 EDO19484.1 - 1.2e-168 559.2 2.8 1.5e-123 411.3 0.6 2.1 2 0 0 2 2 2 2 Phosphofructokinase Glyoxalase_2 PF12681.2 EDO19484.1 - 0.011 16.3 0.0 0.026 15.1 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase-like domain UVR PF02151.14 EDO19484.1 - 0.077 12.5 0.5 0.17 11.4 0.3 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif Inp1 PF12634.2 EDO19485.1 - 4.9e-44 149.5 0.8 4.9e-44 149.5 0.5 3.0 2 1 0 2 2 2 1 Inheritance of peroxisomes protein 1 Med9 PF07544.8 EDO19486.1 - 2.6e-26 91.1 1.3 3.3e-26 90.8 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Whi5 PF08528.6 EDO19487.1 - 4.8e-11 41.9 0.2 9.8e-11 40.9 0.1 1.6 1 0 0 1 1 1 1 Whi5 like XPA_C PF05181.7 EDO19488.1 - 1.2e-26 92.0 0.3 3.3e-26 90.6 0.2 1.8 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EDO19488.1 - 0.0052 16.4 0.6 0.0052 16.4 0.4 2.0 2 0 0 2 2 2 1 XPA protein N-terminal VHS PF00790.14 EDO19489.1 - 7.4e-35 119.6 0.4 7.4e-35 119.6 0.3 2.0 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EDO19489.1 - 1.7e-19 69.4 2.8 4e-19 68.2 2.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EDO19489.1 - 0.00048 19.4 9.8 0.033 13.7 1.2 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif Ta0938 PF11494.3 EDO19489.1 - 0.15 12.1 1.3 0.55 10.3 0.1 2.5 2 0 0 2 2 2 0 Ta0938 Chordopox_A13L PF05961.6 EDO19489.1 - 1.5 8.8 0.0 1.5 8.8 0.0 3.8 4 0 0 4 4 4 0 Chordopoxvirus A13L protein zf-AN1 PF01428.11 EDO19489.1 - 5.4 6.9 13.2 0.3 10.9 5.3 1.8 2 0 0 2 2 2 0 AN1-like Zinc finger zf-RING_5 PF14634.1 EDO19489.1 - 7.1 6.4 11.0 65 3.3 7.5 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Rot1 PF10681.4 EDO19490.1 - 5.8e-95 316.6 0.0 6.7e-95 316.4 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal SOCS PF12610.3 EDO19490.1 - 0.078 13.3 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Suppressor of cytokine signalling Cyclin_N PF00134.18 EDO19491.1 - 8.2e-36 122.3 0.0 2e-35 121.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain BBP1_C PF15272.1 EDO19493.1 - 5.8e-63 212.0 36.8 1.1e-62 211.1 25.5 1.4 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal BBP1_N PF15271.1 EDO19493.1 - 1.3e-54 184.5 0.5 1.3e-54 184.5 0.4 2.8 2 1 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein HisKA_2 PF07568.7 EDO19493.1 - 0.026 14.3 0.6 0.026 14.3 0.4 2.1 2 0 0 2 2 2 0 Histidine kinase SlyX PF04102.7 EDO19493.1 - 5.9 7.3 11.9 6.3 7.2 0.0 3.6 3 1 0 3 3 3 0 SlyX SAGA-Tad1 PF12767.2 EDO19494.1 - 9.1e-75 251.5 0.0 1.2e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 EDO19494.1 - 0.0049 16.1 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TFIID_20kDa PF03847.8 EDO19494.1 - 0.09 13.0 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID_30kDa PF03540.8 EDO19494.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit Myosin_tail_1 PF01576.14 EDO19495.1 - 0.0011 16.8 59.7 0.0015 16.3 41.4 1.1 1 0 0 1 1 1 1 Myosin tail Fer2 PF00111.22 EDO19496.1 - 8.9e-14 51.0 0.5 1.2e-13 50.5 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain V-SNARE_C PF12352.3 EDO19497.1 - 3.1e-20 71.9 3.7 3.1e-20 71.9 2.6 1.9 2 0 0 2 2 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EDO19497.1 - 2.5e-18 66.0 3.5 2.5e-18 66.0 2.4 2.4 3 0 0 3 3 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 EDO19497.1 - 0.00021 20.9 0.7 0.00021 20.9 0.5 2.1 2 0 0 2 2 2 1 Sec20 Snapin_Pallidin PF14712.1 EDO19497.1 - 0.013 15.7 3.5 0.013 15.7 2.4 2.7 2 1 0 2 2 2 0 Snapin/Pallidin Myotub-related PF06602.9 EDO19497.1 - 0.026 13.2 0.7 0.03 13.1 0.5 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain FliJ PF02050.11 EDO19497.1 - 0.15 12.0 12.9 0.089 12.8 1.6 2.4 2 1 0 2 2 2 0 Flagellar FliJ protein T2SF PF00482.18 EDO19497.1 - 0.17 11.7 1.6 0.28 11.1 0.1 2.0 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F Serine_rich PF08824.5 EDO19497.1 - 0.19 11.4 3.7 2.6 7.7 0.2 2.2 1 1 1 2 2 2 0 Serine rich protein interaction domain SNARE PF05739.14 EDO19497.1 - 0.19 11.4 8.6 0.24 11.1 0.5 2.9 2 1 1 3 3 3 0 SNARE domain YqjK PF13997.1 EDO19497.1 - 0.27 11.4 0.0 0.27 11.4 0.0 2.9 3 0 0 3 3 3 0 YqjK-like protein Pepsin-I3 PF06394.8 EDO19497.1 - 0.34 10.5 2.0 0.33 10.6 0.1 2.0 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Use1 PF09753.4 EDO19497.1 - 0.58 9.5 8.9 6 6.2 6.2 2.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 Nsp1_C PF05064.8 EDO19497.1 - 1 8.9 9.4 0.079 12.6 2.0 2.4 2 1 0 2 2 2 0 Nsp1-like C-terminal region DUF4071 PF13281.1 EDO19497.1 - 1.8 7.3 9.3 0.14 10.9 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4071) DUF2408 PF10303.4 EDO19497.1 - 2.8 8.0 8.2 1.2e+02 2.7 5.3 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4615 PF15393.1 EDO19497.1 - 6.1 7.0 8.8 0.98 9.6 1.9 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4615) Glyco_hydro_63 PF03200.11 EDO19498.1 - 0.00052 17.9 16.1 0.0008 17.3 0.4 4.8 5 1 0 5 5 5 3 Mannosyl oligosaccharide glucosidase PITH PF06201.8 EDO19499.1 - 0.068 12.9 0.3 0.08 12.7 0.2 1.1 1 0 0 1 1 1 0 PITH domain Ribosomal_L36e PF01158.13 EDO19500.1 - 3.7e-36 123.0 4.3 4.1e-36 122.8 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e HHH_2 PF12826.2 EDO19500.1 - 0.061 13.2 0.1 0.11 12.3 0.1 1.4 1 1 0 1 1 1 0 Helix-hairpin-helix motif RabGAP-TBC PF00566.13 EDO19501.1 - 1.9e-48 164.8 0.7 1.9e-48 164.8 0.5 3.5 4 0 0 4 4 4 1 Rab-GTPase-TBC domain MtrB PF05440.7 EDO19501.1 - 0.092 12.7 0.1 1 9.4 0.0 2.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B bZIP_2 PF07716.10 EDO19501.1 - 0.42 10.4 14.7 0.52 10.1 1.3 3.2 2 0 0 2 2 2 0 Basic region leucine zipper Helicase_Sgs1 PF11408.3 EDO19502.1 - 6.8e-35 118.7 1.1 2e-34 117.2 0.8 1.9 1 0 0 1 1 1 1 Sgs1 RecQ helicase RQC PF09382.5 EDO19502.1 - 1.3e-27 95.5 0.0 2.7e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 EDO19502.1 - 9.8e-21 73.9 0.0 2.5e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EDO19502.1 - 4.7e-19 68.0 0.0 7.9e-18 64.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Trypan_PARP PF05887.6 EDO19502.1 - 0.001 18.9 14.4 0.001 18.9 10.0 2.7 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) HRDC PF00570.18 EDO19502.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 HRDC domain Neisseria_TspB PF05616.8 EDO19502.1 - 1.1 7.5 25.2 2 6.7 17.5 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein HMG_box PF00505.14 EDO19503.1 - 9e-29 99.5 5.8 1.3e-17 63.8 0.4 2.1 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EDO19503.1 - 8.5e-16 58.0 3.1 6.6e-09 36.0 0.1 2.2 2 0 0 2 2 2 2 HMG-box domain Tol_Tol_Ttg2 PF05494.7 EDO19503.1 - 0.0046 16.5 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 2 Toluene tolerance, Ttg2 Catalase-rel PF06628.7 EDO19503.1 - 0.045 13.6 0.2 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Catalase-related immune-responsive Enkurin PF13864.1 EDO19503.1 - 0.05 13.8 4.1 0.97 9.6 1.5 2.1 2 0 0 2 2 2 0 Calmodulin-binding DUF2185 PF09951.4 EDO19503.1 - 0.12 12.1 0.2 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) DUF1104 PF06518.6 EDO19503.1 - 0.66 10.1 3.4 39 4.4 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1104) zf-C2H2 PF00096.21 EDO19504.1 - 4.7e-07 29.7 13.9 5.4e-06 26.4 2.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO19504.1 - 1.8e-05 24.7 11.9 0.00014 21.9 2.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EDO19504.1 - 0.0023 18.0 3.2 0.0053 16.8 2.2 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EDO19504.1 - 0.063 13.3 6.4 1.4 9.1 0.6 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EDO19504.1 - 0.16 12.3 11.7 0.38 11.1 0.7 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EDO19504.1 - 0.79 9.9 5.9 0.097 12.8 1.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Acetyltransf_1 PF00583.19 EDO19505.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EDO19505.1 - 0.0098 15.8 0.9 0.032 14.1 0.5 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain zf-C2H2 PF00096.21 EDO19506.1 - 1.7e-11 43.7 8.1 2.3e-05 24.4 0.7 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EDO19506.1 - 4.5e-06 26.6 6.6 0.0027 17.9 0.3 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EDO19506.1 - 0.00019 21.5 13.2 0.035 14.4 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EDO19506.1 - 0.0063 16.6 3.8 0.17 12.1 0.5 3.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF1610 PF07754.6 EDO19506.1 - 0.063 13.4 0.4 0.28 11.3 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Zn-ribbon_8 PF09723.5 EDO19506.1 - 0.78 9.7 4.4 5.4 7.0 0.2 2.8 3 0 0 3 3 3 0 Zinc ribbon domain PRP21_like_P PF12230.3 EDO19506.1 - 0.85 9.0 7.2 6.8 6.1 5.0 2.4 1 1 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-H2C2_5 PF13909.1 EDO19506.1 - 2.9 8.3 7.2 4.9 7.5 0.6 3.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Malic_M PF03949.10 EDO19507.1 - 7.3e-76 255.0 0.0 1.1e-75 254.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EDO19507.1 - 4.4e-64 215.4 0.0 7.6e-64 214.6 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.15 EDO19507.1 - 0.013 15.6 0.3 0.83 9.7 0.1 3.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 EDO19507.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ThiF PF00899.16 EDO19508.1 - 8.2e-37 126.0 0.0 1.4e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EDO19508.1 - 0.00013 22.1 0.0 0.00025 21.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EDO19508.1 - 0.0095 15.9 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 EDO19508.1 - 0.015 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EDO19508.1 - 0.036 13.0 0.1 0.054 12.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EDO19508.1 - 0.049 12.3 0.0 0.082 11.5 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.1 EDO19508.1 - 0.052 13.7 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EDO19508.1 - 0.14 11.5 0.2 0.31 10.4 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2370 PF10176.4 EDO19509.1 - 6.9e-68 228.4 0.0 6.9e-68 228.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) DUF2015 PF09435.5 EDO19509.1 - 0.85 9.4 7.2 1.2 8.9 4.2 1.9 1 1 1 2 2 2 0 Fungal protein of unknown function (DUF2015) DUF830 PF05708.7 EDO19510.1 - 0.2 11.6 0.1 0.2 11.6 0.1 1.5 2 0 0 2 2 2 0 Orthopoxvirus protein of unknown function (DUF830) Adap_comp_sub PF00928.16 EDO19511.1 - 3.5e-33 114.8 3.8 1.3e-32 112.9 2.6 2.0 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Nop14 PF04147.7 EDO19511.1 - 1.7 6.4 14.3 2.5 5.8 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EDO19511.1 - 3 7.4 13.2 1.1 8.7 6.4 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF1754 PF08555.5 EDO19511.1 - 3.3 8.3 8.4 9.5 6.8 5.8 1.7 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) CDC45 PF02724.9 EDO19511.1 - 7.5 4.4 12.5 16 3.4 8.6 1.4 1 0 0 1 1 1 0 CDC45-like protein QCR10 PF09796.4 EDO19512.1 - 6.5e-29 99.3 0.1 7.8e-29 99.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) RhodobacterPufX PF11511.3 EDO19512.1 - 0.034 13.5 0.1 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Intrinsic membrane protein PufX UCR_6-4kD PF08997.5 EDO19512.1 - 0.17 11.6 1.6 0.23 11.1 1.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein APS_kinase PF01583.15 EDO19514.1 - 1e-72 242.9 0.0 1.2e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EDO19514.1 - 1.6e-08 34.5 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EDO19514.1 - 8.8e-05 23.3 0.1 0.00018 22.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EDO19514.1 - 0.00016 20.9 0.0 0.00019 20.7 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EDO19514.1 - 0.00036 20.8 0.1 0.00065 20.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EDO19514.1 - 0.00043 19.7 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EDO19514.1 - 0.016 15.5 0.2 0.024 14.9 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EDO19514.1 - 0.029 14.3 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EDO19514.1 - 0.035 14.4 0.0 0.047 13.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EDO19514.1 - 0.039 13.9 0.1 0.082 12.8 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain CPT PF07931.7 EDO19514.1 - 0.071 12.7 0.5 0.33 10.5 0.3 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Snf7 PF03357.16 EDO19515.1 - 9e-32 109.8 26.7 1.1e-31 109.4 17.8 1.6 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 EDO19515.1 - 2.2e-07 30.4 8.3 3.3e-07 29.8 5.8 1.4 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Clathrin_H_link PF13838.1 EDO19515.1 - 0.058 13.2 1.1 0.097 12.5 0.2 1.8 2 0 0 2 2 2 0 Clathrin-H-link DASH_Dad1 PF08649.5 EDO19515.1 - 0.11 12.2 0.8 0.42 10.3 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad1 Hpt PF01627.18 EDO19515.1 - 0.17 11.8 4.4 0.06 13.3 0.4 2.2 2 1 0 2 2 2 0 Hpt domain Uds1 PF15456.1 EDO19515.1 - 0.44 10.5 8.4 0.19 11.7 0.6 2.4 2 1 0 2 2 2 0 Up-regulated During Septation DUF87 PF01935.12 EDO19515.1 - 0.85 9.3 11.3 0.15 11.8 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF87 YlqD PF11068.3 EDO19515.1 - 5.3 7.0 22.1 2.2 8.3 7.6 2.6 1 1 1 2 2 2 0 YlqD protein Ribosomal_S6 PF01250.12 EDO19516.1 - 1.8e-08 34.0 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 PAP2 PF01569.16 EDO19517.1 - 4.5e-13 49.0 7.5 4.5e-13 49.0 5.2 2.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EDO19517.1 - 3.1e-05 23.5 6.7 3.1e-05 23.5 4.6 2.2 2 1 0 2 2 2 1 PAP2 superfamily Peptidase_U4 PF03419.8 EDO19517.1 - 3.8 6.5 6.8 0.28 10.2 0.9 1.8 2 0 0 2 2 2 0 Sporulation factor SpoIIGA TRAM_LAG1_CLN8 PF03798.11 EDO19518.1 - 6.9e-38 130.1 26.5 6.9e-38 130.1 18.4 2.1 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EDO19518.1 - 1.2e-21 75.9 1.0 3.1e-21 74.6 0.7 1.7 1 0 0 1 1 1 1 TRAM1-like protein Ribosomal_S2 PF00318.15 EDO19519.1 - 2.9e-60 203.1 0.0 5.5e-60 202.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S2 FliD_N PF02465.13 EDO19519.1 - 0.32 11.3 2.0 2.6 8.4 0.2 2.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF1599 PF07659.6 EDO19520.1 - 0.0048 16.9 3.6 0.0087 16.1 0.1 2.6 2 1 1 3 3 3 1 Domain of Unknown Function (DUF1599) DUF3983 PF13137.1 EDO19520.1 - 0.046 13.4 0.5 0.092 12.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) Ribosomal_L10 PF00466.15 EDO19521.1 - 2e-16 59.7 0.0 3.1e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Dynactin_p22 PF07426.6 EDO19521.1 - 0.1 11.8 0.1 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Dynactin subunit p22 Pkinase PF00069.20 EDO19522.1 - 1.5e-64 217.6 1.5 4.8e-64 216.0 1.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO19522.1 - 1e-32 113.2 0.3 2.3e-32 112.0 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO19522.1 - 2.5e-07 29.9 0.0 4.8e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EDO19522.1 - 0.01 14.9 0.1 0.018 14.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO19522.1 - 0.022 14.5 0.1 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DAO PF01266.19 EDO19523.1 - 1.9e-55 188.2 0.0 1.4e-33 116.3 0.0 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EDO19523.1 - 4.8e-07 29.7 0.0 2.6e-06 27.3 0.0 2.2 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EDO19523.1 - 0.00015 20.5 0.2 0.0037 15.9 0.2 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 EDO19523.1 - 0.0077 15.3 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EDO19523.1 - 0.048 13.5 0.0 0.36 10.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EDO19523.1 - 0.069 12.9 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EDO19523.1 - 0.083 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SNARE PF05739.14 EDO19524.1 - 1.1e-11 44.1 2.3 1.1e-11 44.1 1.6 3.5 5 0 0 5 5 5 1 SNARE domain Sec20 PF03908.8 EDO19524.1 - 0.00023 20.8 2.3 0.016 14.8 0.0 2.5 2 1 0 2 2 2 1 Sec20 HemX PF04375.9 EDO19524.1 - 0.0081 14.7 3.5 0.32 9.5 0.3 2.0 2 0 0 2 2 2 2 HemX DUF1241 PF06840.6 EDO19524.1 - 0.032 13.4 2.1 1.1 8.5 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1241) Syntaxin_2 PF14523.1 EDO19524.1 - 0.035 14.1 8.4 1.5 8.8 2.6 2.4 2 1 0 2 2 2 0 Syntaxin-like protein Syntaxin-6_N PF09177.6 EDO19524.1 - 0.038 14.3 11.7 0.039 14.3 2.9 3.2 2 1 1 3 3 3 0 Syntaxin 6, N-terminal RmuC PF02646.11 EDO19524.1 - 0.046 12.5 0.2 0.046 12.5 0.1 2.3 2 1 0 2 2 2 0 RmuC family V-SNARE_C PF12352.3 EDO19524.1 - 0.053 13.6 3.6 0.17 11.9 0.5 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus NPV_P10 PF05531.7 EDO19524.1 - 0.066 13.4 4.2 0.2 11.9 0.1 3.0 1 1 3 4 4 4 0 Nucleopolyhedrovirus P10 protein HisKA_3 PF07730.8 EDO19524.1 - 0.081 13.2 0.1 15 6.0 0.1 2.9 3 0 0 3 3 3 0 Histidine kinase WXG100 PF06013.7 EDO19524.1 - 0.12 12.3 1.2 3.8 7.5 0.2 3.0 2 1 0 2 2 2 0 Proteins of 100 residues with WXG PARP_reg PF02877.9 EDO19524.1 - 0.12 12.0 0.2 0.12 12.0 0.2 2.3 2 2 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain FlaC_arch PF05377.6 EDO19524.1 - 0.17 11.7 12.5 0.21 11.4 1.3 3.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Use1 PF09753.4 EDO19524.1 - 0.31 10.4 6.3 6.1 6.1 4.4 2.2 1 1 0 1 1 1 0 Membrane fusion protein Use1 Laminin_II PF06009.7 EDO19524.1 - 0.36 10.5 7.0 11 5.7 2.5 2.8 1 1 0 2 2 2 0 Laminin Domain II MscS_porin PF12795.2 EDO19524.1 - 0.44 9.8 8.4 4.7 6.4 3.0 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF643 PF04867.7 EDO19524.1 - 0.6 10.5 5.6 0.78 10.1 0.8 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF643) IFT57 PF10498.4 EDO19524.1 - 0.63 8.7 14.3 0.058 12.1 0.7 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Seryl_tRNA_N PF02403.17 EDO19524.1 - 0.67 9.9 12.2 0.57 10.2 3.2 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2650 PF10853.3 EDO19524.1 - 1 8.8 4.2 1.6 8.2 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) PDDEXK_1 PF12705.2 EDO19524.1 - 1.5 8.1 4.2 0.85 8.9 1.6 1.5 1 1 1 2 2 2 0 PD-(D/E)XK nuclease superfamily Mnd1 PF03962.10 EDO19524.1 - 2.9 7.5 13.2 0.56 9.8 4.3 2.3 1 1 1 2 2 2 0 Mnd1 family Nup88 PF10168.4 EDO19524.1 - 6.9 4.3 9.7 1.6 6.4 0.1 2.0 1 1 0 2 2 2 0 Nuclear pore component TMPIT PF07851.8 EDO19524.1 - 9.2 5.2 8.9 7.4 5.5 2.3 2.2 1 1 1 2 2 2 0 TMPIT-like protein Dpy-30 PF05186.8 EDO19525.1 - 3.1e-15 55.3 0.1 4.5e-15 54.8 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif Mito_carr PF00153.22 EDO19526.1 - 1.3e-08 34.4 0.0 0.0079 15.8 0.0 3.8 4 0 0 4 4 4 2 Mitochondrial carrier protein Gon7 PF08738.5 EDO19527.1 - 0.0025 17.7 2.7 0.0031 17.4 0.4 2.2 2 0 0 2 2 2 1 Gon7 family DUF1735 PF08522.5 EDO19527.1 - 0.0085 16.4 3.0 0.012 15.9 0.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1735) DUF3467 PF11950.3 EDO19527.1 - 0.071 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) YkyA PF10368.4 EDO19527.1 - 9.3 5.5 19.6 2.6 7.3 5.3 2.6 1 1 2 3 3 3 0 Putative cell-wall binding lipoprotein Ribosomal_L27e PF01777.13 EDO19528.1 - 9.4e-36 121.8 7.4 1.3e-35 121.4 5.1 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EDO19528.1 - 0.00025 20.6 1.2 0.00048 19.7 0.8 1.5 1 0 0 1 1 1 1 KOW motif TRAPP PF04051.11 EDO19529.1 - 2.2e-39 134.4 0.0 3.6e-39 133.7 0.0 1.3 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component Troponin PF00992.15 EDO19530.1 - 0.024 14.7 0.3 0.024 14.7 0.2 3.0 3 0 0 3 3 3 0 Troponin DUF3439 PF11921.3 EDO19530.1 - 1.8 8.3 8.6 4.4 7.0 6.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DDHD PF02862.12 EDO19531.1 - 7e-49 166.6 3.2 1.2e-30 107.0 0.2 2.7 2 1 1 3 3 3 2 DDHD domain LCAT PF02450.10 EDO19531.1 - 0.00013 21.0 0.3 0.0031 16.5 0.0 2.5 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase PGAP1 PF07819.8 EDO19531.1 - 0.00087 18.9 0.2 0.0029 17.2 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF2305 PF10230.4 EDO19531.1 - 0.0015 17.9 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EDO19531.1 - 0.0081 15.9 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family TSC22 PF01166.13 EDO19531.1 - 0.05 13.5 2.0 0.43 10.5 0.1 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Abhydrolase_1 PF00561.15 EDO19531.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2963 PF11178.3 EDO19532.1 - 0.0069 15.7 0.7 0.0069 15.7 0.5 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF2963) Corona_nucleoca PF00937.13 EDO19532.1 - 3.6 6.4 28.7 0.034 13.1 2.0 2.4 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein Pkinase PF00069.20 EDO19533.1 - 1.7e-76 256.7 0.1 2.5e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO19533.1 - 5e-39 133.9 0.0 7.3e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EDO19533.1 - 9.6e-20 70.5 0.6 3.4e-19 68.7 0.4 2.0 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EDO19533.1 - 9.1e-11 41.2 0.0 2.5e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EDO19533.1 - 2.6e-05 23.6 0.8 5e-05 22.7 0.6 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EDO19533.1 - 4.4e-05 22.2 0.6 6.6e-05 21.6 0.4 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EDO19533.1 - 0.0024 17.6 0.0 0.37 10.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EDO19533.1 - 0.0027 16.8 0.1 0.0051 15.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pex24p PF06398.6 EDO19534.1 - 2.7e-84 283.0 6.7 3.2e-84 282.7 4.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin WD40 PF00400.27 EDO19535.1 - 1.1e-07 31.4 14.3 7.2e-05 22.5 0.3 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat NikR_C PF08753.6 EDO19535.1 - 0.016 15.0 0.1 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 NikR C terminal nickel binding domain PQQ PF01011.16 EDO19535.1 - 0.046 13.2 0.1 1.7 8.3 0.0 3.1 3 0 0 3 3 3 0 PQQ enzyme repeat SET PF00856.23 EDO19536.1 - 5.7e-12 46.2 0.0 1.9e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 EDO19537.1 - 1.8e-54 181.2 23.1 1.4e-16 59.8 0.1 6.3 4 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 EDO19537.1 - 1.7e-41 138.1 23.6 1.8e-07 30.4 0.0 9.6 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 EDO19537.1 - 2.5e-34 114.4 20.0 0.00012 21.6 0.1 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EDO19537.1 - 8.7e-23 80.0 6.9 4.6e-09 36.0 0.1 6.1 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EDO19537.1 - 3.2e-21 75.4 4.5 0.00019 21.9 0.0 6.5 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 EDO19537.1 - 3.4e-20 70.2 15.1 0.0059 16.3 0.1 8.1 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EDO19537.1 - 1.3e-19 68.8 8.1 0.023 15.3 0.1 9.2 6 3 4 10 10 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDO19537.1 - 3.4e-14 52.9 11.4 0.015 15.6 0.0 7.3 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDO19537.1 - 4.7e-14 50.9 8.7 0.00034 20.1 0.0 7.0 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDO19537.1 - 1.3e-10 40.6 7.9 0.15 12.3 0.0 8.0 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EDO19537.1 - 1.9e-08 34.3 10.4 0.0033 17.5 0.2 4.6 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EDO19537.1 - 2.2e-08 33.8 0.2 0.00021 21.0 0.0 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EDO19537.1 - 2.1e-05 24.6 17.2 3.1 8.4 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 EDO19537.1 - 0.00014 21.6 0.1 0.61 10.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3808 PF10300.4 EDO19537.1 - 0.00034 19.3 0.1 0.00034 19.3 0.1 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) PPR PF01535.15 EDO19537.1 - 0.029 14.3 5.1 13 6.0 0.0 5.6 6 0 0 6 6 6 0 PPR repeat MAS20 PF02064.10 EDO19537.1 - 0.06 13.2 1.5 2.2 8.2 0.0 3.4 3 0 0 3 3 3 0 MAS20 protein import receptor XPC-binding PF09280.6 EDO19537.1 - 0.49 9.9 10.0 0.11 12.0 3.0 2.6 2 1 0 2 2 2 0 XPC-binding domain DUF648 PF04890.8 EDO19537.1 - 1.3 8.1 8.5 1.2 8.2 1.8 2.4 1 1 0 2 2 2 0 Family of unknown function (DUF648) AAA_2 PF07724.9 EDO19538.1 - 4.1e-51 173.2 0.1 5.6e-49 166.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EDO19538.1 - 1.5e-24 85.7 0.3 5.2e-24 83.9 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EDO19538.1 - 1.7e-21 76.7 0.1 5.7e-11 42.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EDO19538.1 - 9.7e-16 57.7 0.1 7e-12 45.2 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EDO19538.1 - 2.8e-12 46.9 3.7 0.00029 20.8 0.0 4.2 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EDO19538.1 - 2.4e-08 34.1 0.1 0.0022 18.1 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EDO19538.1 - 5.9e-08 32.6 0.1 0.0074 16.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EDO19538.1 - 5.4e-07 30.4 4.4 0.018 15.8 0.0 3.8 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EDO19538.1 - 1.6e-06 27.7 0.0 6.1e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EDO19538.1 - 1.7e-06 27.5 0.0 0.077 12.3 0.0 3.2 3 0 0 3 3 3 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 EDO19538.1 - 1.1e-05 25.2 11.4 0.0011 18.7 0.4 4.8 3 3 0 3 3 2 1 Archaeal ATPase AAA_18 PF13238.1 EDO19538.1 - 2.9e-05 24.3 7.8 0.025 14.8 0.0 3.7 4 1 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.18 EDO19538.1 - 6.2e-05 22.9 0.2 0.02 14.8 0.0 3.1 2 2 1 3 3 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EDO19538.1 - 0.00015 21.0 0.0 0.036 13.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 NACHT PF05729.7 EDO19538.1 - 0.00029 20.5 0.0 0.13 11.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 EDO19538.1 - 0.00034 20.9 3.4 0.2 11.9 0.0 3.5 3 1 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 EDO19538.1 - 0.00043 19.7 0.0 0.1 12.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EDO19538.1 - 0.00045 20.2 0.0 0.45 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EDO19538.1 - 0.00064 19.4 0.0 0.66 9.6 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EDO19538.1 - 0.00066 19.1 0.0 0.41 10.1 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EDO19538.1 - 0.0007 18.7 0.0 0.014 14.5 0.0 2.7 2 1 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 EDO19538.1 - 0.00072 19.7 0.0 1.2 9.2 0.0 3.0 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 EDO19538.1 - 0.00098 18.8 0.0 1.6 8.5 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 EDO19538.1 - 0.0011 18.4 0.1 1.2 8.5 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.1 EDO19538.1 - 0.0032 17.0 0.0 2.6 7.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EDO19538.1 - 0.0035 16.9 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EDO19538.1 - 0.0044 15.9 3.4 0.062 12.1 1.4 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 EDO19538.1 - 0.0053 15.9 0.0 0.6 9.2 0.0 2.9 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EDO19538.1 - 0.0073 15.2 0.7 0.66 8.8 0.1 3.1 2 2 0 2 2 2 1 Protein of unknown function (DUF815) SRP54 PF00448.17 EDO19538.1 - 0.0099 15.3 0.0 1.8 7.9 0.0 2.7 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.1 EDO19538.1 - 0.015 14.8 0.0 6.4 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EDO19538.1 - 0.025 13.7 0.0 2.4 7.3 0.0 2.8 2 0 0 2 2 2 0 PhoH-like protein Miro PF08477.8 EDO19538.1 - 0.025 15.0 0.0 0.73 10.3 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein LacI PF00356.16 EDO19538.1 - 0.026 14.1 0.0 3 7.5 0.0 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Torsin PF06309.6 EDO19538.1 - 0.032 14.1 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_33 PF13671.1 EDO19538.1 - 0.035 14.0 0.0 4.9 7.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EDO19538.1 - 0.052 13.0 0.0 7.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_3 PF07726.6 EDO19538.1 - 0.059 12.9 0.0 1.3 8.5 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1090 PF06476.7 EDO19538.1 - 0.12 12.0 11.7 0.33 10.6 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) Ribosomal_L3 PF00297.17 EDO19539.1 - 7.8e-122 405.7 8.2 9.3e-122 405.4 5.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PHD PF00628.24 EDO19540.1 - 3.5e-08 33.0 7.5 6.5e-08 32.1 5.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EDO19540.1 - 0.0089 16.1 2.4 0.025 14.7 0.2 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain Ecl1 PF12855.2 EDO19540.1 - 0.049 12.9 0.8 0.13 11.5 0.5 1.8 1 0 0 1 1 1 0 Life-span regulatory factor zf-HC5HC2H_2 PF13832.1 EDO19540.1 - 0.29 11.1 3.7 0.19 11.7 0.5 2.0 1 1 1 2 2 2 0 PHD-zinc-finger like domain ING PF12998.2 EDO19540.1 - 0.53 10.5 6.2 1.7 8.9 0.5 2.7 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-RING-like PF08746.6 EDO19540.1 - 2 8.4 6.1 3.9 7.5 4.3 1.5 1 0 0 1 1 1 0 RING-like domain Alg6_Alg8 PF03155.10 EDO19541.1 - 2.7e-157 524.3 46.4 3.2e-157 524.1 32.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF912 PF06024.7 EDO19541.1 - 2.9 7.9 0.0 2.9 7.9 0.0 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Vps5 PF09325.5 EDO19542.1 - 1.4e-44 152.0 6.1 2e-44 151.5 4.3 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EDO19542.1 - 2.2e-23 82.2 0.0 6.3e-23 80.7 0.0 1.8 1 0 0 1 1 1 1 PX domain RabGAP-TBC PF00566.13 EDO19543.1 - 8.2e-51 172.5 1.2 2.2e-50 171.1 0.9 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Brix PF04427.13 EDO19544.1 - 1.6e-37 129.0 2.5 2.2e-37 128.5 1.7 1.2 1 0 0 1 1 1 1 Brix domain Nucleoporin_C PF03177.9 EDO19545.1 - 6e-81 272.7 18.2 7.9e-81 272.3 12.6 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EDO19545.1 - 2.8e-61 207.5 13.8 2.8e-61 207.5 9.6 1.7 2 0 0 2 2 2 1 Nup133 N terminal like DASH_Dad2 PF08654.5 EDO19546.1 - 5.3e-35 119.5 0.8 5.8e-35 119.3 0.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.5 EDO19546.1 - 0.00058 19.3 2.0 0.00075 19.0 1.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DHC_N2 PF08393.8 EDO19546.1 - 0.0065 15.0 0.3 0.0076 14.8 0.2 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Rogdi_lz PF10259.4 EDO19546.1 - 0.023 13.7 0.3 0.028 13.5 0.2 1.0 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein RPW8 PF05659.6 EDO19546.1 - 0.066 12.7 0.5 0.1 12.1 0.3 1.3 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4085 PF13315.1 EDO19546.1 - 0.091 12.1 0.3 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) MCPsignal PF00015.16 EDO19546.1 - 0.094 12.2 0.8 0.12 11.9 0.6 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NTPase_I-T PF01931.13 EDO19546.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF84 Hpr_kinase_C PF07475.7 EDO19546.1 - 0.12 11.7 0.2 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain Shugoshin_N PF07558.6 EDO19547.1 - 3.9e-14 52.0 4.1 3.9e-14 52.0 2.8 2.5 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EDO19547.1 - 3e-10 39.3 5.0 8.4e-10 37.9 3.4 1.8 1 0 0 1 1 1 1 Shugoshin C terminus Daxx PF03344.10 EDO19547.1 - 0.0011 17.5 31.0 0.0018 16.8 21.5 1.4 1 0 0 1 1 1 1 Daxx Family Trypan_PARP PF05887.6 EDO19547.1 - 0.36 10.6 19.6 0.8 9.5 13.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PBP_sp32 PF07222.7 EDO19547.1 - 8.9 5.4 26.1 25 3.9 18.1 1.8 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Thymidylat_synt PF00303.14 EDO19548.1 - 6e-121 402.5 0.0 6.8e-121 402.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Syntaxin-18_N PF10496.4 EDO19549.1 - 1.5e-17 63.1 2.6 1.7e-17 62.9 0.1 2.4 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EDO19549.1 - 3.3e-07 29.8 7.4 1.2e-06 28.1 5.1 2.0 1 0 0 1 1 1 1 SNARE domain MCPsignal PF00015.16 EDO19549.1 - 0.0095 15.4 6.3 0.026 14.0 4.4 1.7 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2533 PF10752.4 EDO19549.1 - 0.24 11.7 0.2 0.24 11.7 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2533) Spore_III_AB PF09548.5 EDO19549.1 - 1.4 8.6 13.6 4.2 7.0 7.3 3.1 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Sec20 PF03908.8 EDO19549.1 - 1.4 8.6 18.3 0.12 12.0 0.5 4.3 2 2 3 5 5 5 0 Sec20 Snapin_Pallidin PF14712.1 EDO19549.1 - 2.6 8.4 25.6 0.23 11.8 4.1 4.3 3 1 1 4 4 4 0 Snapin/Pallidin Peptidase_M41 PF01434.13 EDO19549.1 - 6.3 6.2 13.4 4.8 6.6 1.3 2.4 2 0 0 2 2 2 0 Peptidase family M41 MRP-L20 PF12824.2 EDO19551.1 - 1.1e-51 175.0 2.4 1.3e-51 174.8 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HA2 PF04408.18 EDO19552.1 - 1.3e-25 89.3 0.0 2.5e-24 85.2 0.0 2.9 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EDO19552.1 - 1e-24 86.5 0.0 3.2e-24 84.9 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EDO19552.1 - 4.9e-13 48.7 0.1 2e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EDO19552.1 - 1.9e-05 24.7 0.5 9.1e-05 22.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EDO19552.1 - 5.7e-05 22.6 0.1 0.00015 21.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EDO19552.1 - 0.00059 18.8 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 EDO19552.1 - 0.024 14.0 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EDO19552.1 - 0.043 13.5 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EDO19552.1 - 0.1 12.4 0.1 0.48 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EDO19552.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EDO19552.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_M48 PF01435.13 EDO19553.1 - 6.8e-31 107.5 0.0 1.1e-30 106.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_MA_2 PF13485.1 EDO19553.1 - 0.015 15.3 0.0 0.7 9.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase MA superfamily MtaB PF12176.3 EDO19554.1 - 0.13 10.6 0.0 0.13 10.6 0.0 1.0 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Proteasome PF00227.21 EDO19555.1 - 3.7e-41 140.4 0.0 4.5e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Asp PF00026.18 EDO19555.1 - 0.061 12.5 0.0 0.08 12.1 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Sec7 PF01369.15 EDO19556.1 - 5.6e-26 91.3 0.2 1.3e-25 90.1 0.0 1.7 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 EDO19556.1 - 0.034 14.3 0.2 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain T2SG PF08334.6 EDO19556.1 - 0.051 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein G Sigma70_ner PF04546.8 EDO19556.1 - 0.55 9.8 5.4 15 5.1 0.0 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Rad51 PF08423.6 EDO19557.1 - 1.2e-137 456.9 0.0 1.6e-137 456.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EDO19557.1 - 4.5e-14 52.3 0.0 6.3e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EDO19557.1 - 2.8e-12 46.5 0.2 6.1e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EDO19557.1 - 2.9e-11 43.0 0.0 4.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EDO19557.1 - 2.2e-06 26.9 0.0 3.6e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 EDO19557.1 - 0.026 14.6 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EDO19557.1 - 0.033 13.0 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain HHH PF00633.18 EDO19557.1 - 0.095 12.4 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sel1 PF08238.7 EDO19558.1 - 3.1e-39 132.5 14.5 1.8e-08 34.7 0.6 7.3 7 0 0 7 7 7 7 Sel1 repeat Fungal_trans PF04082.13 EDO19559.1 - 1.3e-20 73.4 5.1 1.3e-20 73.4 3.5 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EDO19559.1 - 6.6e-09 35.5 9.5 1.1e-08 34.7 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UCH PF00443.24 EDO19560.1 - 3.4e-69 232.9 25.9 1e-67 228.0 17.9 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EDO19560.1 - 2.1e-23 83.1 7.1 3.6e-22 79.1 0.3 3.8 1 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ADH_zinc_N_2 PF13602.1 EDO19561.1 - 4e-11 43.9 0.0 7.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EDO19561.1 - 5.4e-06 26.1 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EDO19561.1 - 0.0034 16.9 0.0 0.7 9.4 0.0 3.0 2 1 1 3 3 3 1 Zinc-binding dehydrogenase Ribosomal_S8e PF01201.17 EDO19562.1 - 3e-50 169.7 3.2 3.5e-50 169.5 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e AAR2 PF05282.6 EDO19563.1 - 1.1e-61 208.7 14.7 1.3e-61 208.5 10.2 1.0 1 0 0 1 1 1 1 AAR2 protein HSP70 PF00012.15 EDO19564.1 - 2.9e-271 900.7 10.0 3.3e-271 900.5 7.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EDO19564.1 - 2.3e-16 59.2 0.0 2.7e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EDO19564.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EDO19564.1 - 0.0094 14.8 0.3 0.069 11.9 0.0 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EDO19564.1 - 0.092 11.8 2.5 0.13 11.3 0.1 2.4 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase tRNA-synt_1 PF00133.17 EDO19565.1 - 2e-239 795.6 0.3 3.7e-238 791.4 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDO19565.1 - 1.8e-26 92.6 0.1 5.4e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDO19565.1 - 2.9e-20 72.2 0.6 6.6e-07 28.3 0.3 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EDO19565.1 - 0.00025 20.2 0.0 0.00071 18.7 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Atg8 PF02991.11 EDO19567.1 - 1.1e-50 169.9 0.1 1.2e-50 169.7 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EDO19567.1 - 1.2e-06 28.6 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 MAM1 PF10434.4 EDO19568.1 - 6e-135 448.7 15.9 7.8e-135 448.3 11.0 1.1 1 0 0 1 1 1 1 Monopolin complex protein MAM1 WD40 PF00400.27 EDO19570.1 - 4.7e-27 92.8 12.8 8.7e-07 28.6 0.1 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EDO19570.1 - 7.9e-05 20.9 0.1 0.044 11.9 0.0 2.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EDO19570.1 - 0.00068 19.3 0.1 0.98 9.0 0.0 3.7 2 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A HEAT_EZ PF13513.1 EDO19571.1 - 4.8e-19 68.2 0.3 0.0031 17.9 0.0 8.8 7 2 1 8 8 8 5 HEAT-like repeat HEAT_2 PF13646.1 EDO19571.1 - 1.2e-14 54.2 3.1 0.07 13.4 0.0 7.4 5 1 2 7 7 7 4 HEAT repeats HEAT PF02985.17 EDO19571.1 - 2.9e-12 45.5 0.7 0.073 13.1 0.0 9.1 10 0 0 10 10 10 2 HEAT repeat IBN_N PF03810.14 EDO19571.1 - 4.9e-12 45.5 9.0 8.4e-10 38.4 0.3 5.1 4 1 1 5 5 5 1 Importin-beta N-terminal domain Ipi1_N PF12333.3 EDO19571.1 - 7.1e-05 22.7 1.7 0.39 10.7 0.0 6.2 5 2 2 7 7 7 1 Rix1 complex component involved in 60S ribosome maturation DUF2950 PF11453.3 EDO19571.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) Arm PF00514.18 EDO19571.1 - 0.29 11.0 6.0 6.7 6.6 0.0 5.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ank PF00023.25 EDO19572.1 - 2.5e-12 45.9 4.4 2.7e-05 23.7 0.3 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EDO19572.1 - 2.1e-11 43.9 1.6 0.00015 22.0 0.1 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EDO19572.1 - 6.7e-10 39.2 0.9 4.4e-06 27.0 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EDO19572.1 - 1e-07 31.9 1.2 0.012 15.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EDO19572.1 - 4.6e-07 29.4 0.7 4.6e-07 29.4 0.5 4.0 3 2 0 3 3 3 1 KilA-N domain Ank_3 PF13606.1 EDO19572.1 - 7.3e-07 28.8 4.4 0.021 15.0 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat SpoIISB_antitox PF14185.1 EDO19572.1 - 0.027 14.2 3.1 1.6 8.5 0.0 3.6 3 0 0 3 3 3 0 Antitoxin SpoIISB, type II toxin-antitoxin system TPR_2 PF07719.12 EDO19573.1 - 1.4e-39 130.7 10.5 4.2e-08 32.5 0.1 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 EDO19573.1 - 7.9e-36 121.5 16.4 2.8e-13 49.3 1.5 7.2 4 1 4 8 8 8 5 TPR repeat TPR_1 PF00515.23 EDO19573.1 - 1.9e-33 112.6 17.0 3.7e-09 35.8 0.2 8.4 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.1 EDO19573.1 - 2.6e-28 95.6 3.9 6.5e-06 25.5 0.1 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat Apc3 PF12895.2 EDO19573.1 - 6.5e-28 96.7 30.5 1.1e-15 57.5 1.1 4.8 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EDO19573.1 - 2.2e-24 85.5 0.0 2.7e-08 34.2 0.0 5.4 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EDO19573.1 - 2.7e-21 73.9 14.0 1.3e-05 24.9 0.3 9.5 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EDO19573.1 - 1.2e-17 63.6 13.8 1.6e-06 27.9 0.4 7.1 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EDO19573.1 - 1.8e-17 62.2 0.0 0.0015 19.0 0.0 6.7 3 2 4 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EDO19573.1 - 2.4e-15 56.6 2.5 0.00014 22.1 0.0 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EDO19573.1 - 2.6e-12 45.5 3.5 1 9.2 0.0 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 EDO19573.1 - 6.1e-10 38.9 8.3 0.032 14.6 0.0 7.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EDO19573.1 - 6.3e-10 38.7 0.2 1.3e-05 24.9 0.1 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 EDO19573.1 - 8.3e-06 25.0 0.3 0.15 11.1 0.0 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EDO19573.1 - 0.0022 17.8 4.6 0.11 12.4 0.0 4.1 5 0 0 5 5 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 EDO19573.1 - 0.012 15.3 0.6 33 4.2 0.1 4.4 2 1 2 4 4 4 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 EDO19573.1 - 0.85 9.5 13.0 17 5.3 0.0 5.8 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.7 EDO19573.1 - 1.4 9.6 5.4 24 5.7 0.2 3.6 4 0 0 4 4 3 0 Sel1 repeat TPR_3 PF07720.7 EDO19573.1 - 4.2 7.2 20.8 3.7 7.4 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat PH PF00169.24 EDO19574.1 - 2.7e-14 53.2 0.0 1.6e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.23 EDO19574.1 - 5.8e-12 44.8 0.2 1.4e-11 43.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 EDO19574.1 - 1.7e-11 43.8 0.0 3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EDO19574.1 - 2.8e-09 36.4 0.2 5.2e-09 35.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 EDO19574.1 - 4.1e-08 33.4 2.0 3.7e-07 30.3 0.0 3.6 3 0 0 3 3 3 1 Pleckstrin homology domain SH3_2 PF07653.12 EDO19574.1 - 0.0011 18.4 0.1 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EDO19574.1 - 0.0019 18.3 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EDO19574.1 - 0.003 17.5 0.0 0.097 12.7 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain NT-C2 PF10358.4 EDO19575.1 - 7.3e-44 148.7 0.0 1e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins CARDB PF07705.6 EDO19575.1 - 0.041 13.9 0.1 0.34 10.9 0.0 2.3 2 1 1 3 3 3 0 CARDB Motile_Sperm PF00635.21 EDO19576.1 - 1e-25 89.4 0.4 2.4e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain PapD-like PF14874.1 EDO19576.1 - 0.028 14.3 0.1 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Flagellar-associated PapD-like Ribosomal_L32e PF01655.13 EDO19577.1 - 5.7e-46 155.1 1.9 6.6e-46 154.9 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF3437 PF11919.3 EDO19577.1 - 0.12 12.1 0.3 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) ArfGap PF01412.13 EDO19578.1 - 9.1e-34 115.7 0.3 9.1e-34 115.7 0.2 2.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Flu_B_M2 PF04772.7 EDO19578.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) 4HBT PF03061.17 EDO19579.1 - 4.9e-06 26.5 0.0 1.8e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Thioesterase superfamily AAA PF00004.24 EDO19580.1 - 8e-18 64.9 0.1 2.3e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EDO19580.1 - 0.0002 20.1 0.0 0.0003 19.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EDO19580.1 - 0.00025 21.0 0.2 0.00074 19.5 0.0 1.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EDO19580.1 - 0.00046 19.8 1.5 0.0019 17.9 1.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EDO19580.1 - 0.00092 20.0 0.1 0.0079 17.0 0.0 2.4 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EDO19580.1 - 0.0022 17.0 0.0 0.0037 16.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EDO19580.1 - 0.0028 17.1 0.1 0.006 16.0 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EDO19580.1 - 0.0052 16.5 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EDO19580.1 - 0.0065 16.7 1.2 0.031 14.5 0.0 2.6 2 1 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EDO19580.1 - 0.0078 15.3 0.6 0.018 14.1 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 EDO19580.1 - 0.013 15.6 0.2 0.035 14.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 EDO19580.1 - 0.015 15.2 0.3 0.09 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EDO19580.1 - 0.02 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EDO19580.1 - 0.026 13.6 0.2 0.048 12.8 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EDO19580.1 - 0.069 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EDO19580.1 - 0.073 12.2 0.3 0.14 11.3 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EDO19580.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 EDO19580.1 - 0.14 11.5 0.1 0.38 10.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EDO19580.1 - 0.3 11.1 2.3 0.96 9.4 0.1 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Peptidase_M41 PF01434.13 EDO19581.1 - 2.9e-72 242.6 1.9 4.3e-72 242.0 1.3 1.3 1 0 0 1 1 1 1 Peptidase family M41 Peptidase_M50B PF13398.1 EDO19581.1 - 0.19 11.1 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like ATP-synt_ab PF00006.20 EDO19582.1 - 1.3e-68 230.6 0.0 2e-68 230.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EDO19582.1 - 7e-26 90.9 0.4 1.9e-25 89.4 0.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EDO19582.1 - 5.4e-17 61.7 1.8 1.5e-16 60.3 1.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EDO19582.1 - 0.015 15.2 0.6 0.038 13.8 0.4 1.7 1 0 0 1 1 1 0 HAS barrel domain Tex_N PF09371.5 EDO19582.1 - 0.035 13.4 0.0 0.096 11.9 0.0 1.7 1 0 0 1 1 1 0 Tex-like protein N-terminal domain AAA_25 PF13481.1 EDO19582.1 - 0.078 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arrestin_C PF02752.17 EDO19583.1 - 9.8e-22 77.5 0.2 9.8e-22 77.5 0.1 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EDO19583.1 - 1.1e-11 44.7 0.1 2.5e-10 40.3 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EDO19583.1 - 0.00016 21.2 0.0 0.00045 19.7 0.0 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like DAO PF01266.19 EDO19584.1 - 1.4e-14 53.7 0.0 5.4e-14 51.8 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EDO19584.1 - 0.0069 15.0 0.0 0.017 13.7 0.0 1.6 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EDO19584.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EDO19584.1 - 0.13 12.6 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Oxidored_FMN PF00724.15 EDO19585.1 - 7e-129 429.6 0.0 8e-129 429.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cation_ATPase_N PF00690.21 EDO19585.1 - 0.2 11.1 1.1 0.31 10.5 0.0 1.9 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus RRM_1 PF00076.17 EDO19586.1 - 1.1e-27 95.4 9.2 3.5e-10 39.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO19586.1 - 9e-21 73.6 1.5 1.5e-08 34.4 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO19586.1 - 1.5e-09 37.5 4.2 1.8e-05 24.4 0.8 3.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EDO19586.1 - 0.0019 18.0 0.8 0.13 12.0 0.0 3.4 4 0 0 4 4 4 1 RNA binding motif RNA_bind PF08675.6 EDO19586.1 - 0.0038 17.1 0.0 0.33 10.9 0.0 2.8 2 0 0 2 2 2 1 RNA binding domain DUF3095 PF11294.3 EDO19586.1 - 0.026 13.5 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) Cobl PF09469.5 EDO19586.1 - 0.12 12.3 3.1 0.28 11.2 0.7 2.7 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain DUF1776 PF08643.5 EDO19587.1 - 1.9e-49 168.4 1.9 2.7e-49 167.9 1.3 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Lyase_1 PF00206.15 EDO19588.1 - 3.7e-96 321.9 0.0 1.8e-95 319.7 0.0 1.8 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.1 EDO19588.1 - 4e-26 90.8 0.0 8.6e-26 89.8 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal BBE PF08031.7 EDO19588.1 - 0.23 11.4 2.1 24 4.9 0.1 3.0 3 0 0 3 3 3 0 Berberine and berberine like tRNA-synt_2 PF00152.15 EDO19589.1 - 1.7e-74 250.6 0.0 2.6e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EDO19589.1 - 1.2e-11 44.2 0.2 2.4e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PHP PF02811.14 EDO19590.1 - 1.7e-17 63.7 2.1 9.5e-17 61.3 1.5 2.1 1 1 0 1 1 1 1 PHP domain Enterotoxin_b PF01376.13 EDO19590.1 - 0.08 12.8 0.1 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Heat-labile enterotoxin beta chain Fmp27_WPPW PF10359.4 EDO19591.1 - 7.3e-138 459.9 4.6 1.3e-137 459.0 3.2 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 EDO19591.1 - 6.3e-110 368.1 11.4 6.3e-110 368.1 7.9 2.1 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 EDO19591.1 - 9.8e-50 168.5 0.0 4.1e-49 166.4 0.0 2.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EDO19591.1 - 4.3e-47 159.7 3.4 1.6e-46 157.8 2.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EDO19591.1 - 1.3e-23 83.4 0.1 9.2e-23 80.6 0.0 2.7 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain PH PF00169.24 EDO19594.1 - 2.5e-12 46.9 0.0 6.1e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 PH domain Mito_carr PF00153.22 EDO19595.1 - 1.7e-59 197.4 2.1 1.3e-18 66.5 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF2177 PF09945.4 EDO19595.1 - 0.025 14.5 0.7 0.064 13.2 0.2 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) Tim17 PF02466.14 EDO19595.1 - 0.032 14.2 4.9 1.3 9.1 0.2 3.2 1 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family tRNA-synt_1 PF00133.17 EDO19596.1 - 2.2e-228 759.1 0.2 1.2e-227 756.7 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EDO19596.1 - 7.4e-33 113.4 1.9 2.2e-32 111.9 1.3 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EDO19596.1 - 3.2e-15 55.6 2.5 1.5e-07 30.4 0.0 4.8 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EDO19596.1 - 3.7e-07 29.6 0.0 3.7e-07 29.6 0.0 3.5 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 EDO19596.1 - 0.0016 18.4 8.7 0.0016 18.4 6.0 3.0 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm Flagellin_C PF00700.16 EDO19596.1 - 0.21 11.7 2.2 0.61 10.2 1.5 1.7 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region RRM_1 PF00076.17 EDO19597.1 - 5.9e-70 230.8 11.2 1.7e-17 62.7 0.0 6.5 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EDO19597.1 - 1.3e-63 210.9 3.3 1.6e-15 56.8 0.0 5.8 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO19597.1 - 1.7e-35 120.6 0.1 1.8e-09 37.3 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EDO19597.1 - 0.0037 17.0 0.0 9.3 6.1 0.0 4.1 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif CwfJ_C_1 PF04677.10 EDO19598.1 - 1.8e-33 114.8 2.2 2.8e-33 114.1 0.4 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EDO19598.1 - 2e-22 79.4 4.5 5.9e-22 78.0 3.1 1.9 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF2310 PF10071.4 EDO19598.1 - 0.00067 18.7 0.1 0.0013 17.7 0.1 1.4 1 0 0 1 1 1 1 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) PLA2_B PF01735.13 EDO19598.1 - 0.021 13.0 6.0 0.94 7.5 0.7 2.4 2 0 0 2 2 2 0 Lysophospholipase catalytic domain Pkinase PF00069.20 EDO19599.1 - 1.8e-52 178.1 0.0 1.4e-51 175.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO19599.1 - 8.3e-28 97.1 0.1 7.2e-20 71.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EDO19599.1 - 3.3e-07 30.7 2.1 2.9e-06 27.6 0.4 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDO19599.1 - 0.0016 17.4 0.0 0.011 14.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDO19599.1 - 0.033 13.2 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO19599.1 - 0.065 12.9 0.0 0.33 10.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Nop PF01798.13 EDO19600.1 - 5.9e-37 126.2 1.0 1e-36 125.5 0.0 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain Prp31_C PF09785.4 EDO19600.1 - 6e-32 110.6 3.9 1.2e-31 109.7 2.7 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 EDO19600.1 - 3e-06 26.9 0.1 9.1e-06 25.3 0.1 1.9 1 0 0 1 1 1 1 NOSIC (NUC001) domain FAM110_C PF14160.1 EDO19600.1 - 0.051 14.5 0.4 0.13 13.1 0.2 1.7 1 0 0 1 1 1 0 Centrosome-associated C terminus Fumble PF03630.9 EDO19600.1 - 0.67 8.7 5.2 0.66 8.7 0.9 2.4 2 1 0 2 2 2 0 Fumble RNA_pol_A_bac PF01000.21 EDO19601.1 - 1.7e-30 105.4 0.0 3.4e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EDO19601.1 - 1.5e-15 56.0 0.0 2.9e-15 55.1 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Lipoprotein_20 PF13942.1 EDO19603.1 - 0.012 15.1 1.4 0.012 15.1 1.0 3.5 1 1 2 3 3 3 0 YfhG lipoprotein z-alpha PF02295.12 EDO19603.1 - 4.4 7.1 8.6 0.54 10.0 0.9 3.0 3 0 0 3 3 3 0 Adenosine deaminase z-alpha domain DUF2198 PF09964.4 EDO19603.1 - 6.3 6.6 8.9 24 4.7 0.2 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) zf-CCCH PF00642.19 EDO19604.1 - 1.9e-15 56.1 27.2 0.0035 16.9 0.2 5.5 5 1 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EDO19604.1 - 6.8 6.8 28.9 3 7.9 1.0 5.4 4 1 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type Fork_head PF00250.13 EDO19605.1 - 2.7e-33 113.8 0.4 7.9e-33 112.3 0.3 1.8 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EDO19605.1 - 7.5e-12 45.1 0.4 2.1e-11 43.7 0.3 1.9 1 0 0 1 1 1 1 FHA domain Proteasome PF00227.21 EDO19606.1 - 7.3e-49 165.6 0.1 8.8e-49 165.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Rho_Binding PF08912.6 EDO19607.1 - 0.063 13.5 1.0 0.063 13.5 0.7 1.9 2 0 0 2 2 2 0 Rho Binding DUF4359 PF14271.1 EDO19607.1 - 0.094 13.0 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4359) DUF2862 PF11061.3 EDO19608.1 - 0.042 13.5 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2862) Sdh_cyt PF01127.17 EDO19609.1 - 6.8e-20 71.0 3.7 8.7e-20 70.7 2.6 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Pkinase PF00069.20 EDO19610.1 - 5.8e-70 235.4 0.5 8.1e-70 234.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO19610.1 - 2.2e-33 115.4 0.0 3.7e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EDO19610.1 - 2.2e-05 23.5 0.0 8.3e-05 21.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EDO19610.1 - 0.0079 15.2 0.2 0.074 12.1 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EDO19610.1 - 0.036 13.7 0.5 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EDO19610.1 - 0.037 12.8 0.2 0.068 12.0 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF605 PF04652.11 EDO19610.1 - 4.6 6.5 15.8 6.3 6.0 11.0 1.1 1 0 0 1 1 1 0 Vta1 like BAF1_ABF1 PF04684.8 EDO19610.1 - 5.7 5.6 13.7 9.1 4.9 9.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DASH_Hsk3 PF08227.6 EDO19611.1 - 4.1e-20 71.6 2.9 5.6e-20 71.2 2.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like GvpK PF05121.7 EDO19611.1 - 0.091 12.5 0.2 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Gas vesicle protein K Spc24 PF08286.6 EDO19612.1 - 1.1e-24 86.4 0.0 1.1e-24 86.4 0.0 2.4 2 1 0 2 2 2 1 Spc24 subunit of Ndc80 Filament PF00038.16 EDO19612.1 - 0.0067 15.9 2.2 0.0096 15.4 1.5 1.3 1 0 0 1 1 1 1 Intermediate filament protein Mod_r PF07200.8 EDO19612.1 - 0.022 14.6 4.8 0.13 12.2 1.5 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4559 PF15112.1 EDO19612.1 - 0.2 10.7 4.0 0.27 10.3 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DNA_pol3_a_NII PF11490.3 EDO19612.1 - 0.53 9.9 4.8 0.33 10.5 1.9 1.8 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Adaptin_N PF01602.15 EDO19613.1 - 2.6e-132 441.8 19.8 3.3e-132 441.5 13.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EDO19613.1 - 3.3e-25 88.9 4.1 3.3e-25 88.9 2.8 3.5 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EDO19613.1 - 1.9e-13 50.4 0.4 4.2e-07 30.1 0.0 5.4 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.17 EDO19613.1 - 2.4e-10 39.5 2.3 0.0077 16.2 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat Arm PF00514.18 EDO19613.1 - 0.00016 21.3 1.3 0.0022 17.7 0.2 3.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EDO19613.1 - 0.0014 19.0 0.5 4.2 7.9 0.0 3.9 4 0 0 4 4 4 2 HEAT-like repeat Ssl1 PF04056.9 EDO19613.1 - 0.029 13.9 1.3 1 8.9 0.0 2.9 3 0 0 3 3 3 0 Ssl1-like Atx10homo_assoc PF09759.4 EDO19613.1 - 2 8.1 6.5 1.1 8.9 0.1 3.7 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain TPR_12 PF13424.1 EDO19614.1 - 0.0025 17.7 2.4 3 7.8 0.0 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF159 PF02586.9 EDO19615.1 - 4.2e-59 199.5 0.2 5.4e-59 199.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Toxin_8 PF07365.7 EDO19615.1 - 0.061 13.2 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Alpha conotoxin precursor Dynamin_N PF00350.18 EDO19615.1 - 0.13 12.0 1.1 0.24 11.2 0.7 1.5 1 1 0 1 1 1 0 Dynamin family Med11 PF10280.4 EDO19616.1 - 3.2e-25 88.4 3.0 3.6e-25 88.2 2.1 1.0 1 0 0 1 1 1 1 Mediator complex protein ING PF12998.2 EDO19616.1 - 0.00094 19.4 0.9 0.0016 18.6 0.6 1.7 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Med29 PF11568.3 EDO19616.1 - 0.019 15.0 0.1 0.023 14.7 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 29 RPW8 PF05659.6 EDO19616.1 - 0.024 14.1 0.3 0.065 12.7 0.1 1.7 1 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Stap_Strp_tox_C PF02876.12 EDO19616.1 - 0.04 14.0 0.2 0.065 13.3 0.1 1.4 1 1 0 1 1 1 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Tup_N PF08581.5 EDO19616.1 - 0.063 13.4 1.0 0.077 13.2 0.0 1.7 2 1 0 2 2 2 0 Tup N-terminal YtzH PF14165.1 EDO19616.1 - 1.4 9.1 5.0 2.4 8.4 0.4 2.2 2 0 0 2 2 2 0 YtzH-like protein She2p PF11435.3 EDO19617.1 - 1.6e-95 318.3 14.2 1.9e-95 318.1 9.9 1.1 1 0 0 1 1 1 1 RNA binding protein She2p Myosin_head PF00063.16 EDO19618.1 - 5.2e-226 751.9 9.4 8.5e-226 751.2 6.5 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EDO19618.1 - 1.5e-48 164.7 4.5 4.5e-48 163.2 1.2 2.4 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 EDO19618.1 - 8.8e-12 44.2 0.0 1.7e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EDO19618.1 - 2.4e-09 36.6 0.1 5.3e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EDO19618.1 - 6.6e-08 31.9 0.0 1.7e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EDO19618.1 - 0.0022 18.1 0.3 0.0068 16.5 0.2 1.9 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 EDO19618.1 - 0.0042 17.2 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EDO19618.1 - 0.02 14.0 0.4 0.061 12.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EDO19618.1 - 0.034 13.9 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EDO19618.1 - 0.048 13.3 0.0 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 EDO19618.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 EDO19618.1 - 0.062 14.1 0.0 0.27 12.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain IQ PF00612.22 EDO19618.1 - 4 7.3 14.6 1.8 8.3 4.3 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif His_Phos_1 PF00300.17 EDO19619.1 - 9.1e-17 61.5 0.0 1.5e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MraZ PF02381.13 EDO19619.1 - 0.14 11.9 0.2 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 MraZ protein Ku PF02735.11 EDO19620.1 - 3.6e-28 98.3 0.3 7.3e-28 97.3 0.2 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EDO19620.1 - 1.1e-17 64.2 0.2 2.1e-17 63.2 0.2 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 EDO19620.1 - 0.039 14.0 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain PGM_PMM_I PF02878.11 EDO19621.1 - 1.2e-34 118.7 0.1 2.1e-34 117.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EDO19621.1 - 4e-25 88.0 0.0 7e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EDO19621.1 - 1.3e-12 47.8 0.0 3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EDO19621.1 - 2.5e-09 37.0 0.0 5.7e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.20 EDO19622.1 - 2e-69 233.6 0.0 5.2e-69 232.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EDO19622.1 - 1.8e-31 109.1 0.0 2.8e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EDO19622.1 - 1.8e-09 37.9 0.5 5.3e-09 36.4 0.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EDO19622.1 - 0.023 13.6 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EDO19622.1 - 0.094 11.7 0.1 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SPRY PF00622.23 EDO19623.1 - 4e-12 46.3 0.0 7.8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 SPRY domain WD40 PF00400.27 EDO19624.1 - 1.4e-24 84.9 15.3 9e-08 31.7 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Mito_carr PF00153.22 EDO19625.1 - 1.8e-60 200.6 3.8 5.8e-22 77.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Vma12 PF11712.3 EDO19626.1 - 6.1e-39 132.9 1.4 8.9e-39 132.4 1.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3169 PF11368.3 EDO19626.1 - 0.0014 17.8 2.7 0.002 17.3 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) DUF2207 PF09972.4 EDO19626.1 - 0.009 14.6 0.9 0.011 14.4 0.6 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DnaG_DnaB_bind PF08278.6 EDO19626.1 - 0.011 15.9 0.2 0.018 15.2 0.1 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding MscS_TM PF12794.2 EDO19626.1 - 0.015 13.9 0.8 0.015 13.9 0.6 1.7 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 PIRT PF15099.1 EDO19626.1 - 0.032 13.4 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family SseC PF04888.7 EDO19626.1 - 0.06 12.6 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DUF4231 PF14015.1 EDO19626.1 - 0.63 10.0 3.7 1 9.3 2.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Hydrolase_3 PF08282.7 EDO19626.1 - 0.72 9.3 5.0 0.95 8.9 3.4 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldose_epim PF01263.15 EDO19627.1 - 1.2e-41 142.8 0.3 1.4e-41 142.5 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_72 PF03198.9 EDO19628.1 - 1.5e-143 477.5 6.6 2e-143 477.1 4.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EDO19628.1 - 0.00035 19.8 0.2 0.0021 17.3 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EDO19628.1 - 0.0018 17.2 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Nop14 PF04147.7 EDO19628.1 - 0.017 13.0 2.3 0.024 12.6 1.6 1.1 1 0 0 1 1 1 0 Nop14-like family Sec3_C PF09763.4 EDO19628.1 - 1.4 6.9 8.7 1.9 6.5 6.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Apt1 PF10351.4 EDO19628.1 - 2.2 7.0 21.5 3.1 6.5 14.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.4 EDO19628.1 - 3.1 5.9 27.9 4.3 5.5 19.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4614 PF15391.1 EDO19628.1 - 6.3 6.5 27.0 16 5.2 18.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) bZIP_1 PF00170.16 EDO19629.1 - 1.7e-06 27.9 3.4 1.7e-06 27.9 2.3 2.7 2 1 1 3 3 2 1 bZIP transcription factor bZIP_2 PF07716.10 EDO19629.1 - 0.0011 18.7 5.7 0.0042 16.8 1.2 2.5 2 0 0 2 2 2 1 Basic region leucine zipper Glutaredoxin2_C PF04399.8 EDO19629.1 - 0.013 15.0 1.9 0.033 13.7 1.3 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain CENP-Q PF13094.1 EDO19629.1 - 0.13 12.2 8.2 0.22 11.5 5.7 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Cas_GSU0053 PF09617.5 EDO19629.1 - 0.14 11.9 2.3 12 5.6 0.0 2.3 1 1 0 2 2 2 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Atg14 PF10186.4 EDO19629.1 - 0.16 10.8 11.2 0.24 10.3 7.8 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3452 PF11934.3 EDO19629.1 - 0.16 11.2 1.9 0.27 10.5 1.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) Toxin_52 PF15605.1 EDO19629.1 - 0.32 10.8 5.8 0.3 11.0 2.4 2.1 1 1 0 2 2 2 0 Putative toxin 52 TK PF00265.13 EDO19629.1 - 0.37 10.3 6.2 0.13 11.7 1.2 2.3 1 1 0 2 2 2 0 Thymidine kinase V_ATPase_I PF01496.14 EDO19629.1 - 0.47 8.2 7.1 0.53 8.0 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EDO19629.1 - 0.52 9.8 4.1 0.75 9.3 2.8 1.4 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EDO19629.1 - 1.1 9.6 10.3 1.2 9.4 6.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EDO19629.1 - 2.7 8.3 7.3 9.3 6.6 4.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Uds1 PF15456.1 EDO19629.1 - 3 7.8 10.2 5.6 6.9 1.7 2.4 2 0 0 2 2 2 0 Up-regulated During Septation LETM1 PF07766.8 EDO19630.1 - 2.4e-102 341.5 4.6 3.9e-102 340.8 3.2 1.3 1 0 0 1 1 1 1 LETM1-like protein TOM13 PF08219.6 EDO19631.1 - 1.2e-26 92.2 0.2 1.3e-26 92.1 0.1 1.0 1 0 0 1 1 1 1 Outer membrane protein TOM13 DUF1635 PF07795.6 EDO19632.1 - 0.0079 15.5 2.0 0.012 15.0 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) Zip PF02535.17 EDO19632.1 - 0.02 13.9 0.7 0.03 13.3 0.5 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter NusG PF02357.14 EDO19632.1 - 0.053 13.7 0.1 0.087 13.0 0.1 1.4 1 0 0 1 1 1 0 Transcription termination factor nusG PAP1 PF08601.5 EDO19632.1 - 0.35 10.4 16.6 0.49 10.0 11.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Neur_chan_memb PF02932.11 EDO19632.1 - 1.5 8.6 10.4 2.8 7.7 7.1 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DAG_kinase_N PF14513.1 EDO19632.1 - 4.6 7.4 7.5 1.3 9.2 2.7 1.8 1 1 1 2 2 2 0 Diacylglycerol kinase N-terminus rve PF00665.21 EDO19635.1 - 1.5e-16 60.5 0.0 3.6e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EDO19635.1 - 1.5e-15 56.5 0.0 6e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 GAG-pre-integrase domain rve_3 PF13683.1 EDO19635.1 - 0.14 11.6 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Yae1_N PF09811.4 EDO19636.1 - 6.7e-13 47.9 0.0 1.7e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Cep57_CLD_2 PF14197.1 EDO19636.1 - 0.036 14.0 0.9 0.072 13.0 0.6 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 AAA PF00004.24 EDO19637.1 - 4.8e-16 59.1 0.1 1.7e-15 57.3 0.0 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EDO19637.1 - 8.8e-14 51.4 0.0 3.2e-13 49.6 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EDO19637.1 - 3.6e-13 49.0 0.3 5.2e-08 32.0 0.0 2.3 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EDO19637.1 - 1.3e-12 47.5 0.0 3.1e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_11 PF13086.1 EDO19637.1 - 2e-06 27.5 0.1 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EDO19637.1 - 2.8e-06 27.4 0.0 2.3e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EDO19637.1 - 4.6e-06 25.8 0.0 1.2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EDO19637.1 - 5.3e-05 23.2 0.1 0.0017 18.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EDO19637.1 - 7.8e-05 21.9 0.0 0.0032 16.6 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EDO19637.1 - 0.00028 20.7 0.0 0.00073 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EDO19637.1 - 0.00032 20.3 0.0 0.02 14.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EDO19637.1 - 0.00034 20.3 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 EDO19637.1 - 0.0015 18.1 0.6 0.0043 16.6 0.4 1.9 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EDO19637.1 - 0.0043 16.7 0.5 1.2 8.8 0.0 2.8 1 1 2 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 EDO19637.1 - 0.005 17.6 0.0 0.022 15.6 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_23 PF13476.1 EDO19637.1 - 0.0055 17.0 0.2 0.012 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EDO19637.1 - 0.009 15.8 0.2 0.071 12.9 0.0 2.4 2 2 2 4 4 4 1 Type III restriction enzyme, res subunit TIP49 PF06068.8 EDO19637.1 - 0.01 14.6 0.1 1 7.9 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus DUF815 PF05673.8 EDO19637.1 - 0.012 14.5 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF2075 PF09848.4 EDO19637.1 - 0.014 14.4 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EDO19637.1 - 0.014 14.8 0.0 0.057 12.8 0.0 2.2 1 1 0 1 1 1 0 AAA-like domain IFT20 PF14931.1 EDO19637.1 - 0.016 15.1 0.2 0.032 14.1 0.1 1.6 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 AAA_18 PF13238.1 EDO19637.1 - 0.025 14.8 0.8 0.17 12.1 0.5 2.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EDO19637.1 - 0.027 14.6 0.0 0.33 11.1 0.0 2.4 2 1 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 EDO19637.1 - 0.033 13.6 0.1 0.27 10.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EDO19637.1 - 0.041 13.6 0.2 0.32 10.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) SNF2_N PF00176.18 EDO19637.1 - 0.042 12.6 0.0 0.54 8.9 0.0 2.2 1 1 1 2 2 2 0 SNF2 family N-terminal domain AAA_28 PF13521.1 EDO19637.1 - 0.096 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EDO19637.1 - 0.1 12.2 0.0 0.91 9.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EDO19637.1 - 0.16 11.4 0.1 0.42 10.0 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family MipZ PF09140.6 EDO19638.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 ATPase MipZ Xpo1 PF08389.7 EDO19639.1 - 6.5e-36 123.4 2.6 6.5e-36 123.4 1.8 2.9 3 0 0 3 3 3 1 Exportin 1-like protein ATP-gua_PtransN PF02807.10 EDO19639.1 - 0.0071 16.4 0.1 0.067 13.3 0.0 2.6 3 0 0 3 3 3 1 ATP:guanido phosphotransferase, N-terminal domain Ham1p_like PF01725.11 EDO19640.1 - 1e-53 181.5 0.1 1.1e-53 181.3 0.1 1.0 1 0 0 1 1 1 1 Ham1 family DUF1666 PF07891.7 EDO19640.1 - 0.022 14.1 0.1 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1666) PAC2 PF09754.4 EDO19641.1 - 2.6e-37 128.7 0.0 3.2e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 PAC2 family UBN_AB PF14075.1 EDO19641.1 - 0.0078 15.9 0.2 0.13 11.9 0.0 2.0 2 0 0 2 2 2 1 Ubinuclein conserved middle domain DUF4569 PF15133.1 EDO19641.1 - 0.055 12.8 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) ATP_bind_1 PF03029.12 EDO19642.1 - 9.5e-84 280.6 0.4 1.3e-83 280.2 0.3 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EDO19642.1 - 3.1e-08 33.2 0.5 5.1e-08 32.5 0.0 1.5 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 EDO19642.1 - 1.1e-07 31.4 0.7 1.6e-06 27.6 0.5 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EDO19642.1 - 1.7e-05 24.9 0.0 0.0002 21.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EDO19642.1 - 5.7e-05 23.9 4.2 0.00011 23.0 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.1 EDO19642.1 - 0.00011 21.8 0.0 0.00032 20.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EDO19642.1 - 0.00016 20.5 0.1 0.076 11.7 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_33 PF13671.1 EDO19642.1 - 0.00023 21.0 0.0 0.00064 19.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EDO19642.1 - 0.00024 21.0 0.3 0.00089 19.2 0.1 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRP54 PF00448.17 EDO19642.1 - 0.00029 20.3 0.0 0.07 12.5 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 EDO19642.1 - 0.0003 20.2 0.2 0.0088 15.5 0.0 2.5 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EDO19642.1 - 0.00062 19.0 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_10 PF12846.2 EDO19642.1 - 0.00067 19.1 1.9 0.009 15.4 1.3 2.1 1 1 0 1 1 1 1 AAA-like domain NACHT PF05729.7 EDO19642.1 - 0.00093 18.8 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain cobW PF02492.14 EDO19642.1 - 0.0026 17.2 0.1 0.032 13.6 0.1 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EDO19642.1 - 0.0036 17.5 0.0 0.0036 17.5 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EDO19642.1 - 0.0051 16.8 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 EDO19642.1 - 0.015 15.8 1.4 0.47 10.9 0.1 2.6 2 1 0 2 2 1 0 Miro-like protein Glyco_tranf_2_3 PF13641.1 EDO19642.1 - 0.018 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF258 PF03193.11 EDO19642.1 - 0.022 13.9 0.1 0.22 10.7 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EDO19642.1 - 0.025 14.2 0.3 0.059 13.0 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EDO19642.1 - 0.032 13.8 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EDO19642.1 - 0.033 13.3 0.0 0.077 12.1 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF87 PF01935.12 EDO19642.1 - 0.034 13.9 0.3 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 Arf PF00025.16 EDO19642.1 - 0.039 13.2 0.0 2.8 7.1 0.0 2.6 2 1 0 2 2 2 0 ADP-ribosylation factor family SRPRB PF09439.5 EDO19642.1 - 0.05 12.8 4.7 0.34 10.0 0.0 2.8 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EDO19642.1 - 0.054 13.4 0.0 0.14 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain FadA PF09403.5 EDO19642.1 - 0.19 11.7 6.8 0.5 10.3 3.1 2.5 1 1 1 2 2 2 0 Adhesion protein FadA ATP-synt_E PF05680.7 EDO19642.1 - 0.77 9.7 3.4 2.2 8.2 2.4 1.7 1 0 0 1 1 1 0 ATP synthase E chain DUF106 PF01956.11 EDO19643.1 - 1.9e-56 190.1 0.9 2.8e-56 189.6 0.6 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 ABC_membrane PF00664.18 EDO19645.1 - 1.6e-81 273.7 29.1 1.9e-45 155.4 6.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EDO19645.1 - 2.1e-64 215.9 0.3 1.1e-33 116.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EDO19645.1 - 1.8e-11 43.7 8.2 0.00022 20.5 1.7 4.4 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EDO19645.1 - 1.1e-09 37.6 1.4 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EDO19645.1 - 1.6e-09 37.1 0.0 0.00071 18.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EDO19645.1 - 5e-09 37.0 0.5 0.002 18.9 0.1 3.3 2 1 1 3 3 2 2 AAA domain AAA_22 PF13401.1 EDO19645.1 - 1.7e-08 34.6 3.3 0.0025 17.9 0.3 4.3 2 2 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EDO19645.1 - 8.2e-08 32.0 0.0 0.0046 16.4 0.0 3.4 3 0 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 EDO19645.1 - 1.1e-07 32.1 0.1 0.017 15.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EDO19645.1 - 2.8e-07 29.5 1.7 0.029 12.9 0.0 3.8 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EDO19645.1 - 6.3e-07 29.5 0.7 0.048 13.6 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 EDO19645.1 - 1.2e-06 27.7 0.0 0.017 14.1 0.0 2.7 2 1 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.18 EDO19645.1 - 1.9e-06 27.8 0.5 0.097 12.6 0.2 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 EDO19645.1 - 2.1e-06 27.9 9.2 0.08 12.8 0.1 4.9 3 2 1 4 4 3 2 AAA domain DUF87 PF01935.12 EDO19645.1 - 6.9e-06 26.0 0.2 0.02 14.6 0.0 3.0 2 0 0 2 2 2 2 Domain of unknown function DUF87 DUF3987 PF13148.1 EDO19645.1 - 1.8e-05 23.4 0.0 0.11 11.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_25 PF13481.1 EDO19645.1 - 7e-05 22.3 0.0 0.41 10.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 EDO19645.1 - 7.9e-05 23.0 6.5 0.13 12.5 0.4 3.4 4 0 0 4 4 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EDO19645.1 - 7.9e-05 22.2 0.0 0.27 10.7 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 EDO19645.1 - 0.0001 22.0 0.1 0.35 10.5 0.0 3.0 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EDO19645.1 - 0.00024 20.9 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EDO19645.1 - 0.00025 20.8 0.0 1.1 8.9 0.0 3.2 4 0 0 4 4 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EDO19645.1 - 0.00033 20.5 0.5 2.8 7.8 0.0 4.2 4 0 0 4 4 3 1 AAA domain ATP-synt_ab PF00006.20 EDO19645.1 - 0.00035 20.1 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.1 EDO19645.1 - 0.00038 19.0 0.2 0.007 14.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EDO19645.1 - 0.00044 19.9 0.1 0.34 10.5 0.0 2.9 2 0 0 2 2 2 1 NACHT domain APS_kinase PF01583.15 EDO19645.1 - 0.00083 19.0 0.8 0.65 9.6 0.0 2.7 3 0 0 3 3 2 2 Adenylylsulphate kinase RNA_helicase PF00910.17 EDO19645.1 - 0.001 19.2 0.0 2.9 8.0 0.0 2.8 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 EDO19645.1 - 0.0011 17.9 0.0 1.3 7.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein NB-ARC PF00931.17 EDO19645.1 - 0.0011 17.8 0.7 1.5 7.6 0.0 3.1 3 0 0 3 3 3 2 NB-ARC domain Septin PF00735.13 EDO19645.1 - 0.0017 17.3 0.2 1.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Septin Miro PF08477.8 EDO19645.1 - 0.0024 18.3 0.1 1.3 9.5 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein NTPase_1 PF03266.10 EDO19645.1 - 0.003 17.2 0.1 2 8.0 0.0 3.4 3 0 0 3 3 3 1 NTPase KaiC PF06745.8 EDO19645.1 - 0.0075 15.4 1.3 2.7 7.0 0.0 2.9 3 0 0 3 3 2 1 KaiC SbcCD_C PF13558.1 EDO19645.1 - 0.011 15.6 0.1 6.1 6.8 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EDO19645.1 - 0.011 15.2 0.0 7.9 6.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.21 EDO19645.1 - 0.015 14.7 0.0 6 6.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 EDO19645.1 - 0.039 13.3 0.1 0.35 10.2 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase AAA_24 PF13479.1 EDO19645.1 - 0.07 12.6 0.6 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Gly_transf_sug PF04488.10 EDO19646.1 - 8.9e-13 48.5 0.0 4e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3373 PF11853.3 EDO19646.1 - 0.0026 16.3 0.1 0.0036 15.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3373) DDE_Tnp_1_2 PF13586.1 EDO19646.1 - 0.024 14.8 0.3 0.055 13.6 0.2 1.5 1 0 0 1 1 1 0 Transposase DDE domain UTP15_C PF09384.5 EDO19646.1 - 0.046 13.4 0.3 0.6 9.7 0.8 2.1 2 0 0 2 2 2 0 UTP15 C terminal MgtE_N PF03448.12 EDO19646.1 - 0.054 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 MgtE intracellular N domain HXXSHH PF07586.6 EDO19646.1 - 0.12 11.3 0.4 0.18 10.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Radial_spoke PF04712.7 EDO19646.1 - 0.4 9.3 5.2 1 8.0 0.0 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein Septin PF00735.13 EDO19647.1 - 6.9e-107 356.6 0.4 1.2e-106 355.8 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EDO19647.1 - 1.2e-06 28.4 0.0 3e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EDO19647.1 - 1.8e-05 23.9 0.0 4.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EDO19647.1 - 6.3e-05 22.8 5.6 0.0026 17.5 0.2 2.8 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EDO19647.1 - 0.00026 20.2 1.0 0.002 17.3 0.7 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 EDO19647.1 - 0.00099 18.0 0.1 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_10 PF12846.2 EDO19647.1 - 0.0094 15.4 0.1 0.011 15.2 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain Miro PF08477.8 EDO19647.1 - 0.016 15.7 0.0 0.039 14.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EDO19647.1 - 0.032 14.5 0.1 0.095 13.0 0.0 1.8 2 0 0 2 2 2 0 ABC transporter DUF2286 PF10051.4 EDO19647.1 - 0.048 13.2 0.4 4.6 6.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2286) IGPS PF00218.16 EDO19648.1 - 1.9e-90 302.3 0.1 2.5e-90 301.9 0.1 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 EDO19648.1 - 8.4e-55 185.2 0.1 1.4e-54 184.5 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EDO19648.1 - 9.9e-09 34.9 0.1 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 EDO19648.1 - 0.00044 19.8 0.2 0.0029 17.1 0.1 2.3 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain Pneumovirus_M2 PF06436.6 EDO19648.1 - 0.027 13.7 0.1 0.11 11.6 0.0 1.9 1 1 1 2 2 2 0 Pneumovirus matrix protein 2 (M2) Peripla_BP_2 PF01497.13 EDO19648.1 - 0.041 13.0 0.0 0.09 11.8 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein Antimicrobial10 PF08105.6 EDO19648.1 - 0.079 12.6 0.0 0.86 9.2 0.0 2.5 3 0 0 3 3 3 0 Metchnikowin family FoP_duplication PF13865.1 EDO19649.1 - 1.7e-06 28.4 8.4 6.6e-06 26.4 5.8 1.8 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.17 EDO19649.1 - 0.0054 16.3 0.1 0.0091 15.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EDO19649.1 - 0.012 15.4 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EDO19649.1 - 0.098 12.4 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Limkain b1 OB_RNB PF08206.6 EDO19649.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Ribonuclease B OB domain Mito_carr PF00153.22 EDO19650.1 - 9.2e-51 169.5 7.1 1.4e-19 69.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein T4_gp9_10 PF07880.6 EDO19650.1 - 0.076 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T4 gp9/10-like protein Flocculin PF00624.13 EDO19651.1 - 5.3e-136 442.2 325.4 5.4e-17 61.3 21.5 11.5 11 1 0 11 11 11 10 Flocculin repeat Flocculin PF00624.13 EDO19652.1 - 1.8e-21 75.7 40.2 2.6e-14 52.7 11.4 7.7 4 1 3 7 7 7 3 Flocculin repeat MFS_1 PF07690.11 EDO19653.1 - 2.1e-37 128.6 33.4 2.1e-37 128.6 23.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EDO19653.1 - 0.00044 18.5 4.5 0.00073 17.8 3.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EDO19653.1 - 0.0016 16.5 8.9 0.018 13.1 3.8 3.1 1 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family